data_9NTI
# 
_entry.id   9NTI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NTI         pdb_00009nti 10.2210/pdb9nti/pdb 
WWPDB D_1000294098 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-25 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NTI 
_pdbx_database_status.recvd_initial_deposition_date   2025-03-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              xcheng5@mdanderson.org 
_pdbx_contact_author.name_first         Xiaodong 
_pdbx_contact_author.name_last          Cheng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6967-6362 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kaur, G.'     1 ? 
'Horton, J.R.' 2 ? 
'Cheng, X.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Biol.Chem. 
_citation.journal_id_ASTM           JBCHA3 
_citation.journal_id_CSD            0071 
_citation.journal_id_ISSN           1083-351X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                110357 
_citation.page_last                 110357 
_citation.title                     
'Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jbc.2025.110357 
_citation.pdbx_database_id_PubMed   40505866 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kaur, G.'        1 ? 
primary 'Horton, J.R.'    2 ? 
primary 'Tzertzinis, G.'  3 ? 
primary 'Zhou, J.'        4 ? 
primary 'Schildkraut, I.' 5 ? 
primary 'Cheng, X.'       6 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Adenosine deaminase AGSA,Adenosine deaminase AGSA,Chimeric adenosine deaminase growth factor' 61383.203 2 
3.5.4.4 ? 'residues 1-120,residues 254-525' 
;residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA,residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA,residues 1-120 of A. californica AGSA, followed by active site region of H. pomatia Adenosine deaminase growth factor, followed by residues 254-525 of A. californica AGSA
;
2 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose                                                       221.208   6 ? ? ? 
? 
3 non-polymer syn 'ZINC ION'                                                                                     65.409    2 ? ? ? 
? 
4 water       nat water                                                                                          18.015    3 ? ? ? 
? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Atrial gland-specific antigen,AGSA,Mollusk-derived growth factor,MDGF' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPA
NSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFR
SDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYP
DFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRF
TELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQ
LALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPA
NSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFR
SDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYP
DFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRF
TELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQ
LALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
3 'ZINC ION'                               ZN  
4 water                                    HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   SER n 
1 4   PHE n 
1 5   SER n 
1 6   THR n 
1 7   HIS n 
1 8   ASN n 
1 9   PHE n 
1 10  VAL n 
1 11  ALA n 
1 12  ILE n 
1 13  ALA n 
1 14  THR n 
1 15  PHE n 
1 16  VAL n 
1 17  CYS n 
1 18  TRP n 
1 19  PHE n 
1 20  CYS n 
1 21  CYS n 
1 22  LEU n 
1 23  ALA n 
1 24  THR n 
1 25  ALA n 
1 26  ALA n 
1 27  PRO n 
1 28  LEU n 
1 29  THR n 
1 30  SER n 
1 31  LYS n 
1 32  ALA n 
1 33  ALA n 
1 34  TYR n 
1 35  LEU n 
1 36  LEU n 
1 37  LYS n 
1 38  ARG n 
1 39  ASN n 
1 40  SER n 
1 41  LEU n 
1 42  ILE n 
1 43  GLU n 
1 44  GLU n 
1 45  ASP n 
1 46  ALA n 
1 47  SER n 
1 48  ARG n 
1 49  LYS n 
1 50  LEU n 
1 51  GLY n 
1 52  ALA n 
1 53  LYS n 
1 54  ILE n 
1 55  VAL n 
1 56  LEU n 
1 57  THR n 
1 58  ASN n 
1 59  GLU n 
1 60  GLU n 
1 61  LYS n 
1 62  VAL n 
1 63  LEU n 
1 64  ASP n 
1 65  ASP n 
1 66  PHE n 
1 67  ILE n 
1 68  LEU n 
1 69  ALA n 
1 70  GLU n 
1 71  LYS n 
1 72  ARG n 
1 73  LYS n 
1 74  LEU n 
1 75  ILE n 
1 76  ASP n 
1 77  ASP n 
1 78  SER n 
1 79  ARG n 
1 80  LEU n 
1 81  ASN n 
1 82  GLN n 
1 83  THR n 
1 84  GLU n 
1 85  TYR n 
1 86  MET n 
1 87  PRO n 
1 88  ALA n 
1 89  ALA n 
1 90  SER n 
1 91  PHE n 
1 92  TYR n 
1 93  ARG n 
1 94  SER n 
1 95  LYS n 
1 96  ASP n 
1 97  PHE n 
1 98  ILE n 
1 99  ASP n 
1 100 THR n 
1 101 THR n 
1 102 PHE n 
1 103 ALA n 
1 104 TYR n 
1 105 LYS n 
1 106 ILE n 
1 107 ILE n 
1 108 GLN n 
1 109 ASP n 
1 110 MET n 
1 111 PRO n 
1 112 LYS n 
1 113 GLY n 
1 114 GLY n 
1 115 ALA n 
1 116 LEU n 
1 117 HIS n 
1 118 LEU n 
1 119 HIS n 
1 120 ASP n 
1 121 THR n 
1 122 ALA n 
1 123 SER n 
1 124 ALA n 
1 125 ARG n 
1 126 ILE n 
1 127 ASP n 
1 128 TRP n 
1 129 ILE n 
1 130 VAL n 
1 131 SER n 
1 132 ASN n 
1 133 ALA n 
1 134 THR n 
1 135 TYR n 
1 136 ARG n 
1 137 ASP n 
1 138 HIS n 
1 139 VAL n 
1 140 TYR n 
1 141 MET n 
1 142 CYS n 
1 143 MET n 
1 144 ASP n 
1 145 GLN n 
1 146 ASP n 
1 147 ASN n 
1 148 PHE n 
1 149 VAL n 
1 150 ARG n 
1 151 LEU n 
1 152 THR n 
1 153 VAL n 
1 154 SER n 
1 155 GLY n 
1 156 THR n 
1 157 GLY n 
1 158 PRO n 
1 159 PRO n 
1 160 ALA n 
1 161 ASN n 
1 162 SER n 
1 163 GLY n 
1 164 CYS n 
1 165 GLU n 
1 166 TRP n 
1 167 LYS n 
1 168 LEU n 
1 169 VAL n 
1 170 GLU n 
1 171 THR n 
1 172 GLU n 
1 173 ARG n 
1 174 ALA n 
1 175 ASN n 
1 176 SER n 
1 177 GLY n 
1 178 ASP n 
1 179 ILE n 
1 180 ALA n 
1 181 ALA n 
1 182 PHE n 
1 183 ASP n 
1 184 HIS n 
1 185 TRP n 
1 186 LEU n 
1 187 LYS n 
1 188 SER n 
1 189 ASN n 
1 190 ILE n 
1 191 SER n 
1 192 LEU n 
1 193 LEU n 
1 194 THR n 
1 195 THR n 
1 196 ASP n 
1 197 PRO n 
1 198 LEU n 
1 199 VAL n 
1 200 THR n 
1 201 TYR n 
1 202 PRO n 
1 203 SER n 
1 204 LEU n 
1 205 ASP n 
1 206 LYS n 
1 207 VAL n 
1 208 TRP n 
1 209 GLY n 
1 210 ARG n 
1 211 PHE n 
1 212 ASP n 
1 213 LYS n 
1 214 HIS n 
1 215 PHE n 
1 216 SER n 
1 217 GLN n 
1 218 LEU n 
1 219 ARG n 
1 220 GLY n 
1 221 ILE n 
1 222 ILE n 
1 223 TYR n 
1 224 HIS n 
1 225 THR n 
1 226 PRO n 
1 227 ILE n 
1 228 ARG n 
1 229 ARG n 
1 230 ASP n 
1 231 TYR n 
1 232 TYR n 
1 233 ARG n 
1 234 GLN n 
1 235 ILE n 
1 236 LEU n 
1 237 GLU n 
1 238 GLU n 
1 239 PHE n 
1 240 ARG n 
1 241 SER n 
1 242 ASP n 
1 243 ASN n 
1 244 VAL n 
1 245 GLN n 
1 246 TYR n 
1 247 VAL n 
1 248 GLU n 
1 249 VAL n 
1 250 ARG n 
1 251 SER n 
1 252 SER n 
1 253 LEU n 
1 254 SER n 
1 255 GLY n 
1 256 PHE n 
1 257 PHE n 
1 258 GLU n 
1 259 LEU n 
1 260 ASP n 
1 261 GLY n 
1 262 THR n 
1 263 VAL n 
1 264 HIS n 
1 265 ASP n 
1 266 ALA n 
1 267 GLU n 
1 268 PHE n 
1 269 GLY n 
1 270 LEU n 
1 271 ASN n 
1 272 LEU n 
1 273 TYR n 
1 274 LYS n 
1 275 SER n 
1 276 VAL n 
1 277 THR n 
1 278 GLU n 
1 279 GLU n 
1 280 PHE n 
1 281 GLN n 
1 282 ARG n 
1 283 GLU n 
1 284 TYR n 
1 285 PRO n 
1 286 ASP n 
1 287 PHE n 
1 288 ILE n 
1 289 GLY n 
1 290 ALA n 
1 291 LYS n 
1 292 ILE n 
1 293 ILE n 
1 294 LEU n 
1 295 SER n 
1 296 GLY n 
1 297 LEU n 
1 298 ARG n 
1 299 PHE n 
1 300 LYS n 
1 301 SER n 
1 302 GLN n 
1 303 GLU n 
1 304 GLU n 
1 305 ILE n 
1 306 LEU n 
1 307 ASN n 
1 308 GLU n 
1 309 VAL n 
1 310 LYS n 
1 311 ILE n 
1 312 ALA n 
1 313 MET n 
1 314 ASP n 
1 315 LEU n 
1 316 HIS n 
1 317 LYS n 
1 318 LYS n 
1 319 TYR n 
1 320 PRO n 
1 321 ASP n 
1 322 PHE n 
1 323 PHE n 
1 324 LEU n 
1 325 GLY n 
1 326 TYR n 
1 327 ASP n 
1 328 LEU n 
1 329 VAL n 
1 330 GLY n 
1 331 GLN n 
1 332 GLU n 
1 333 ASP n 
1 334 PRO n 
1 335 ASN n 
1 336 PHE n 
1 337 SER n 
1 338 LEU n 
1 339 LEU n 
1 340 HIS n 
1 341 TYR n 
1 342 LEU n 
1 343 ASP n 
1 344 ALA n 
1 345 LEU n 
1 346 LEU n 
1 347 TYR n 
1 348 PRO n 
1 349 SER n 
1 350 ILE n 
1 351 GLN n 
1 352 ASN n 
1 353 PRO n 
1 354 PRO n 
1 355 TYR n 
1 356 ARG n 
1 357 LEU n 
1 358 PRO n 
1 359 TYR n 
1 360 PHE n 
1 361 PHE n 
1 362 HIS n 
1 363 ALA n 
1 364 ALA n 
1 365 GLU n 
1 366 THR n 
1 367 ASN n 
1 368 TRP n 
1 369 GLN n 
1 370 GLU n 
1 371 THR n 
1 372 GLU n 
1 373 VAL n 
1 374 ASP n 
1 375 TYR n 
1 376 ASN n 
1 377 LEU n 
1 378 ALA n 
1 379 ASP n 
1 380 ALA n 
1 381 LEU n 
1 382 LEU n 
1 383 LEU n 
1 384 ASN n 
1 385 THR n 
1 386 THR n 
1 387 ARG n 
1 388 VAL n 
1 389 GLY n 
1 390 HIS n 
1 391 GLY n 
1 392 PHE n 
1 393 ALA n 
1 394 LEU n 
1 395 ILE n 
1 396 LYS n 
1 397 HIS n 
1 398 PRO n 
1 399 ARG n 
1 400 PHE n 
1 401 THR n 
1 402 GLU n 
1 403 LEU n 
1 404 ALA n 
1 405 LYS n 
1 406 GLU n 
1 407 ASN n 
1 408 GLY n 
1 409 VAL n 
1 410 ALA n 
1 411 VAL n 
1 412 GLU n 
1 413 VAL n 
1 414 ASN n 
1 415 PRO n 
1 416 ILE n 
1 417 SER n 
1 418 ASN n 
1 419 GLN n 
1 420 ILE n 
1 421 LEU n 
1 422 GLY n 
1 423 LEU n 
1 424 VAL n 
1 425 ARG n 
1 426 ASP n 
1 427 VAL n 
1 428 ARG n 
1 429 ASN n 
1 430 HIS n 
1 431 ALA n 
1 432 LEU n 
1 433 VAL n 
1 434 PRO n 
1 435 LEU n 
1 436 ILE n 
1 437 ALA n 
1 438 ASP n 
1 439 ASP n 
1 440 TYR n 
1 441 PRO n 
1 442 ILE n 
1 443 VAL n 
1 444 ILE n 
1 445 SER n 
1 446 SER n 
1 447 ASP n 
1 448 ASP n 
1 449 PRO n 
1 450 GLY n 
1 451 ALA n 
1 452 TRP n 
1 453 GLU n 
1 454 ALA n 
1 455 SER n 
1 456 PRO n 
1 457 LEU n 
1 458 SER n 
1 459 HIS n 
1 460 ASP n 
1 461 PHE n 
1 462 TYR n 
1 463 VAL n 
1 464 ALA n 
1 465 LEU n 
1 466 MET n 
1 467 ASP n 
1 468 LEU n 
1 469 CYS n 
1 470 GLY n 
1 471 ARG n 
1 472 ASP n 
1 473 THR n 
1 474 ALA n 
1 475 LEU n 
1 476 THR n 
1 477 PHE n 
1 478 LEU n 
1 479 LYS n 
1 480 GLN n 
1 481 LEU n 
1 482 ALA n 
1 483 LEU n 
1 484 ASN n 
1 485 SER n 
1 486 ILE n 
1 487 ARG n 
1 488 TYR n 
1 489 SER n 
1 490 ALA n 
1 491 MET n 
1 492 SER n 
1 493 ASP n 
1 494 THR n 
1 495 GLU n 
1 496 LYS n 
1 497 VAL n 
1 498 ALA n 
1 499 ALA n 
1 500 LYS n 
1 501 ALA n 
1 502 LYS n 
1 503 TRP n 
1 504 THR n 
1 505 THR n 
1 506 GLN n 
1 507 TRP n 
1 508 ASP n 
1 509 LYS n 
1 510 PHE n 
1 511 VAL n 
1 512 LYS n 
1 513 THR n 
1 514 SER n 
1 515 VAL n 
1 516 GLU n 
1 517 GLY n 
1 518 LEU n 
1 519 LYS n 
1 520 PRO n 
1 521 HIS n 
1 522 ILE n 
1 523 ASN n 
1 524 ASP n 
1 525 ARG n 
1 526 SER n 
1 527 HIS n 
1 528 HIS n 
1 529 HIS n 
1 530 HIS n 
1 531 HIS n 
1 532 HIS n 
1 533 HIS n 
1 534 HIS n 
1 535 HIS n 
1 536 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   120 'California sea hare' ? ? ? ? ? ? ? ? 'Aplysia californica' 6500 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 121 254 ?                     ? ? ? ? ? ? ? ? 'Aplysia californica' 6500 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 255 536 'California sea hare' ? ? ? ? ? ? ? ? 'Aplysia californica' 6500 ? ? ? ? ? ? ? ? 
'Komagataella pastoris' 4922 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                  . WATER                                    ? 'H2 O'           18.015  
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
ZN  non-polymer                  . 'ZINC ION'                               ? 'Zn 2'           65.409  
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   PHE 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   ?   ?   ?   A . n 
A 1 7   HIS 7   7   ?   ?   ?   A . n 
A 1 8   ASN 8   8   ?   ?   ?   A . n 
A 1 9   PHE 9   9   ?   ?   ?   A . n 
A 1 10  VAL 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  ILE 12  12  ?   ?   ?   A . n 
A 1 13  ALA 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  PHE 15  15  ?   ?   ?   A . n 
A 1 16  VAL 16  16  ?   ?   ?   A . n 
A 1 17  CYS 17  17  ?   ?   ?   A . n 
A 1 18  TRP 18  18  ?   ?   ?   A . n 
A 1 19  PHE 19  19  ?   ?   ?   A . n 
A 1 20  CYS 20  20  ?   ?   ?   A . n 
A 1 21  CYS 21  21  ?   ?   ?   A . n 
A 1 22  LEU 22  22  ?   ?   ?   A . n 
A 1 23  ALA 23  23  ?   ?   ?   A . n 
A 1 24  THR 24  24  ?   ?   ?   A . n 
A 1 25  ALA 25  25  ?   ?   ?   A . n 
A 1 26  ALA 26  26  ?   ?   ?   A . n 
A 1 27  PRO 27  27  ?   ?   ?   A . n 
A 1 28  LEU 28  28  ?   ?   ?   A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  SER 30  30  30  SER SER A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  ALA 32  32  32  ALA ALA A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LYS 37  37  37  LYS LYS A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ASP 45  45  45  ASP ASP A . n 
A 1 46  ALA 46  46  46  ALA ALA A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  LYS 49  49  49  LYS LYS A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  LYS 53  53  53  LYS LYS A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  LEU 56  56  56  LEU LEU A . n 
A 1 57  THR 57  57  57  THR THR A . n 
A 1 58  ASN 58  58  58  ASN ASN A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLU 60  60  60  GLU GLU A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  ASP 64  64  64  ASP ASP A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  LYS 71  71  71  LYS LYS A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  ILE 75  75  75  ILE ILE A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  ASP 77  77  77  ASP ASP A . n 
A 1 78  SER 78  78  78  SER SER A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  ASN 81  81  81  ASN ASN A . n 
A 1 82  GLN 82  82  82  GLN GLN A . n 
A 1 83  THR 83  83  83  THR THR A . n 
A 1 84  GLU 84  84  84  GLU GLU A . n 
A 1 85  TYR 85  85  85  TYR TYR A . n 
A 1 86  MET 86  86  86  MET MET A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  PHE 97  97  97  PHE PHE A . n 
A 1 98  ILE 98  98  98  ILE ILE A . n 
A 1 99  ASP 99  99  99  ASP ASP A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 PHE 102 102 102 PHE PHE A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 TYR 104 104 104 TYR TYR A . n 
A 1 105 LYS 105 105 105 LYS LYS A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 GLN 108 108 108 GLN GLN A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 PRO 111 111 111 PRO PRO A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 GLY 113 113 113 GLY GLY A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 HIS 117 117 117 HIS HIS A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 HIS 119 119 119 HIS HIS A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 THR 121 121 121 THR THR A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 ILE 126 126 126 ILE ILE A . n 
A 1 127 ASP 127 127 127 ASP ASP A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 ASN 132 132 132 ASN ASN A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 TYR 135 135 135 TYR TYR A . n 
A 1 136 ARG 136 136 136 ARG ARG A . n 
A 1 137 ASP 137 137 137 ASP ASP A . n 
A 1 138 HIS 138 138 138 HIS HIS A . n 
A 1 139 VAL 139 139 139 VAL VAL A . n 
A 1 140 TYR 140 140 140 TYR TYR A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 CYS 142 142 142 CYS CYS A . n 
A 1 143 MET 143 143 143 MET MET A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 GLN 145 145 145 GLN GLN A . n 
A 1 146 ASP 146 146 146 ASP ASP A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 GLY 155 155 155 GLY GLY A . n 
A 1 156 THR 156 156 156 THR THR A . n 
A 1 157 GLY 157 157 157 GLY GLY A . n 
A 1 158 PRO 158 158 158 PRO PRO A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 ASN 161 161 161 ASN ASN A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 GLY 163 163 163 GLY GLY A . n 
A 1 164 CYS 164 164 164 CYS CYS A . n 
A 1 165 GLU 165 165 165 GLU GLU A . n 
A 1 166 TRP 166 166 166 TRP TRP A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 LEU 168 168 168 LEU LEU A . n 
A 1 169 VAL 169 169 169 VAL VAL A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 GLU 172 172 172 GLU GLU A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 GLY 177 177 177 GLY GLY A . n 
A 1 178 ASP 178 178 178 ASP ASP A . n 
A 1 179 ILE 179 179 179 ILE ILE A . n 
A 1 180 ALA 180 180 180 ALA ALA A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 PHE 182 182 182 PHE PHE A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 HIS 184 184 184 HIS HIS A . n 
A 1 185 TRP 185 185 185 TRP TRP A . n 
A 1 186 LEU 186 186 186 LEU LEU A . n 
A 1 187 LYS 187 187 187 LYS LYS A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 THR 200 200 200 THR THR A . n 
A 1 201 TYR 201 201 201 TYR TYR A . n 
A 1 202 PRO 202 202 202 PRO PRO A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 ASP 205 205 205 ASP ASP A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 VAL 207 207 207 VAL VAL A . n 
A 1 208 TRP 208 208 208 TRP TRP A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 ARG 210 210 210 ARG ARG A . n 
A 1 211 PHE 211 211 211 PHE PHE A . n 
A 1 212 ASP 212 212 212 ASP ASP A . n 
A 1 213 LYS 213 213 213 LYS LYS A . n 
A 1 214 HIS 214 214 214 HIS HIS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 ARG 219 219 219 ARG ARG A . n 
A 1 220 GLY 220 220 220 GLY GLY A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 TYR 223 223 223 TYR TYR A . n 
A 1 224 HIS 224 224 224 HIS HIS A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 PRO 226 226 226 PRO PRO A . n 
A 1 227 ILE 227 227 227 ILE ILE A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 ASP 230 230 230 ASP ASP A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 TYR 232 232 232 TYR TYR A . n 
A 1 233 ARG 233 233 233 ARG ARG A . n 
A 1 234 GLN 234 234 234 GLN GLN A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 GLU 237 237 237 GLU GLU A . n 
A 1 238 GLU 238 238 238 GLU GLU A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 ARG 240 240 240 ARG ARG A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 ASN 243 243 243 ASN ASN A . n 
A 1 244 VAL 244 244 244 VAL VAL A . n 
A 1 245 GLN 245 245 245 GLN GLN A . n 
A 1 246 TYR 246 246 246 TYR TYR A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 GLY 255 255 255 GLY GLY A . n 
A 1 256 PHE 256 256 256 PHE PHE A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 ASP 260 260 260 ASP ASP A . n 
A 1 261 GLY 261 261 261 GLY GLY A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 VAL 263 263 263 VAL VAL A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 ASP 265 265 265 ASP ASP A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 GLU 267 267 267 GLU GLU A . n 
A 1 268 PHE 268 268 268 PHE PHE A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 ASN 271 271 271 ASN ASN A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 TYR 273 273 273 TYR TYR A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 THR 277 277 277 THR THR A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 GLU 279 279 279 GLU GLU A . n 
A 1 280 PHE 280 280 280 PHE PHE A . n 
A 1 281 GLN 281 281 281 GLN GLN A . n 
A 1 282 ARG 282 282 282 ARG ARG A . n 
A 1 283 GLU 283 283 283 GLU GLU A . n 
A 1 284 TYR 284 284 284 TYR TYR A . n 
A 1 285 PRO 285 285 285 PRO PRO A . n 
A 1 286 ASP 286 286 286 ASP ASP A . n 
A 1 287 PHE 287 287 287 PHE PHE A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 GLY 289 289 289 GLY GLY A . n 
A 1 290 ALA 290 290 290 ALA ALA A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 ILE 292 292 292 ILE ILE A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 GLN 302 302 302 GLN GLN A . n 
A 1 303 GLU 303 303 303 GLU GLU A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 ILE 305 305 305 ILE ILE A . n 
A 1 306 LEU 306 306 306 LEU LEU A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 VAL 309 309 309 VAL VAL A . n 
A 1 310 LYS 310 310 310 LYS LYS A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 ALA 312 312 312 ALA ALA A . n 
A 1 313 MET 313 313 313 MET MET A . n 
A 1 314 ASP 314 314 314 ASP ASP A . n 
A 1 315 LEU 315 315 315 LEU LEU A . n 
A 1 316 HIS 316 316 316 HIS HIS A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 TYR 319 319 319 TYR TYR A . n 
A 1 320 PRO 320 320 320 PRO PRO A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 PHE 323 323 323 PHE PHE A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 GLY 325 325 325 GLY GLY A . n 
A 1 326 TYR 326 326 326 TYR TYR A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 VAL 329 329 329 VAL VAL A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 GLN 331 331 331 GLN GLN A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 ASP 333 333 333 ASP ASP A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 ASN 335 335 335 ASN ASN A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 SER 337 337 337 SER SER A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 HIS 340 340 340 HIS HIS A . n 
A 1 341 TYR 341 341 341 TYR TYR A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 ALA 344 344 344 ALA ALA A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 TYR 347 347 347 TYR TYR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 SER 349 349 349 SER SER A . n 
A 1 350 ILE 350 350 350 ILE ILE A . n 
A 1 351 GLN 351 351 351 GLN GLN A . n 
A 1 352 ASN 352 352 352 ASN ASN A . n 
A 1 353 PRO 353 353 353 PRO PRO A . n 
A 1 354 PRO 354 354 354 PRO PRO A . n 
A 1 355 TYR 355 355 355 TYR TYR A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 TYR 359 359 359 TYR TYR A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 PHE 361 361 361 PHE PHE A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 ALA 363 363 363 ALA ALA A . n 
A 1 364 ALA 364 364 364 ALA ALA A . n 
A 1 365 GLU 365 365 365 GLU GLU A . n 
A 1 366 THR 366 366 366 THR THR A . n 
A 1 367 ASN 367 367 367 ASN ASN A . n 
A 1 368 TRP 368 368 368 TRP TRP A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 GLU 370 370 370 GLU GLU A . n 
A 1 371 THR 371 371 371 THR THR A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 TYR 375 375 375 TYR TYR A . n 
A 1 376 ASN 376 376 376 ASN ASN A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 ALA 378 378 378 ALA ALA A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 THR 385 385 385 THR THR A . n 
A 1 386 THR 386 386 386 THR THR A . n 
A 1 387 ARG 387 387 387 ARG ARG A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 HIS 390 390 390 HIS HIS A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 ALA 393 393 393 ALA ALA A . n 
A 1 394 LEU 394 394 394 LEU LEU A . n 
A 1 395 ILE 395 395 395 ILE ILE A . n 
A 1 396 LYS 396 396 396 LYS LYS A . n 
A 1 397 HIS 397 397 397 HIS HIS A . n 
A 1 398 PRO 398 398 398 PRO PRO A . n 
A 1 399 ARG 399 399 399 ARG ARG A . n 
A 1 400 PHE 400 400 400 PHE PHE A . n 
A 1 401 THR 401 401 401 THR THR A . n 
A 1 402 GLU 402 402 402 GLU GLU A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 ALA 404 404 404 ALA ALA A . n 
A 1 405 LYS 405 405 405 LYS LYS A . n 
A 1 406 GLU 406 406 406 GLU GLU A . n 
A 1 407 ASN 407 407 407 ASN ASN A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 ALA 410 410 410 ALA ALA A . n 
A 1 411 VAL 411 411 411 VAL VAL A . n 
A 1 412 GLU 412 412 412 GLU GLU A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 ASN 414 414 414 ASN ASN A . n 
A 1 415 PRO 415 415 415 PRO PRO A . n 
A 1 416 ILE 416 416 416 ILE ILE A . n 
A 1 417 SER 417 417 417 SER SER A . n 
A 1 418 ASN 418 418 418 ASN ASN A . n 
A 1 419 GLN 419 419 419 GLN GLN A . n 
A 1 420 ILE 420 420 420 ILE ILE A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 GLY 422 422 422 GLY GLY A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 VAL 424 424 424 VAL VAL A . n 
A 1 425 ARG 425 425 425 ARG ARG A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 VAL 427 427 427 VAL VAL A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 ASN 429 429 429 ASN ASN A . n 
A 1 430 HIS 430 430 430 HIS HIS A . n 
A 1 431 ALA 431 431 431 ALA ALA A . n 
A 1 432 LEU 432 432 432 LEU LEU A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 PRO 434 434 434 PRO PRO A . n 
A 1 435 LEU 435 435 435 LEU LEU A . n 
A 1 436 ILE 436 436 436 ILE ILE A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 ASP 438 438 438 ASP ASP A . n 
A 1 439 ASP 439 439 439 ASP ASP A . n 
A 1 440 TYR 440 440 440 TYR TYR A . n 
A 1 441 PRO 441 441 441 PRO PRO A . n 
A 1 442 ILE 442 442 442 ILE ILE A . n 
A 1 443 VAL 443 443 443 VAL VAL A . n 
A 1 444 ILE 444 444 444 ILE ILE A . n 
A 1 445 SER 445 445 445 SER SER A . n 
A 1 446 SER 446 446 446 SER SER A . n 
A 1 447 ASP 447 447 447 ASP ASP A . n 
A 1 448 ASP 448 448 448 ASP ASP A . n 
A 1 449 PRO 449 449 449 PRO PRO A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 ALA 451 451 451 ALA ALA A . n 
A 1 452 TRP 452 452 452 TRP TRP A . n 
A 1 453 GLU 453 453 453 GLU GLU A . n 
A 1 454 ALA 454 454 454 ALA ALA A . n 
A 1 455 SER 455 455 455 SER SER A . n 
A 1 456 PRO 456 456 456 PRO PRO A . n 
A 1 457 LEU 457 457 457 LEU LEU A . n 
A 1 458 SER 458 458 458 SER SER A . n 
A 1 459 HIS 459 459 459 HIS HIS A . n 
A 1 460 ASP 460 460 460 ASP ASP A . n 
A 1 461 PHE 461 461 461 PHE PHE A . n 
A 1 462 TYR 462 462 462 TYR TYR A . n 
A 1 463 VAL 463 463 463 VAL VAL A . n 
A 1 464 ALA 464 464 464 ALA ALA A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 MET 466 466 466 MET MET A . n 
A 1 467 ASP 467 467 467 ASP ASP A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 CYS 469 469 469 CYS CYS A . n 
A 1 470 GLY 470 470 470 GLY GLY A . n 
A 1 471 ARG 471 471 471 ARG ARG A . n 
A 1 472 ASP 472 472 472 ASP ASP A . n 
A 1 473 THR 473 473 473 THR THR A . n 
A 1 474 ALA 474 474 474 ALA ALA A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 PHE 477 477 477 PHE PHE A . n 
A 1 478 LEU 478 478 478 LEU LEU A . n 
A 1 479 LYS 479 479 479 LYS LYS A . n 
A 1 480 GLN 480 480 480 GLN GLN A . n 
A 1 481 LEU 481 481 481 LEU LEU A . n 
A 1 482 ALA 482 482 482 ALA ALA A . n 
A 1 483 LEU 483 483 483 LEU LEU A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 SER 485 485 485 SER SER A . n 
A 1 486 ILE 486 486 486 ILE ILE A . n 
A 1 487 ARG 487 487 487 ARG ARG A . n 
A 1 488 TYR 488 488 488 TYR TYR A . n 
A 1 489 SER 489 489 489 SER SER A . n 
A 1 490 ALA 490 490 490 ALA ALA A . n 
A 1 491 MET 491 491 491 MET MET A . n 
A 1 492 SER 492 492 492 SER SER A . n 
A 1 493 ASP 493 493 493 ASP ASP A . n 
A 1 494 THR 494 494 494 THR THR A . n 
A 1 495 GLU 495 495 495 GLU GLU A . n 
A 1 496 LYS 496 496 496 LYS LYS A . n 
A 1 497 VAL 497 497 497 VAL VAL A . n 
A 1 498 ALA 498 498 498 ALA ALA A . n 
A 1 499 ALA 499 499 499 ALA ALA A . n 
A 1 500 LYS 500 500 500 LYS LYS A . n 
A 1 501 ALA 501 501 501 ALA ALA A . n 
A 1 502 LYS 502 502 502 LYS LYS A . n 
A 1 503 TRP 503 503 503 TRP TRP A . n 
A 1 504 THR 504 504 504 THR THR A . n 
A 1 505 THR 505 505 505 THR THR A . n 
A 1 506 GLN 506 506 506 GLN GLN A . n 
A 1 507 TRP 507 507 507 TRP TRP A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 LYS 509 509 509 LYS LYS A . n 
A 1 510 PHE 510 510 510 PHE PHE A . n 
A 1 511 VAL 511 511 511 VAL VAL A . n 
A 1 512 LYS 512 512 512 LYS LYS A . n 
A 1 513 THR 513 513 513 THR THR A . n 
A 1 514 SER 514 514 514 SER SER A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 GLU 516 516 516 GLU GLU A . n 
A 1 517 GLY 517 517 517 GLY GLY A . n 
A 1 518 LEU 518 518 518 LEU LEU A . n 
A 1 519 LYS 519 519 519 LYS LYS A . n 
A 1 520 PRO 520 520 520 PRO PRO A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 ILE 522 522 ?   ?   ?   A . n 
A 1 523 ASN 523 523 ?   ?   ?   A . n 
A 1 524 ASP 524 524 ?   ?   ?   A . n 
A 1 525 ARG 525 525 ?   ?   ?   A . n 
A 1 526 SER 526 526 ?   ?   ?   A . n 
A 1 527 HIS 527 527 ?   ?   ?   A . n 
A 1 528 HIS 528 528 ?   ?   ?   A . n 
A 1 529 HIS 529 529 ?   ?   ?   A . n 
A 1 530 HIS 530 530 ?   ?   ?   A . n 
A 1 531 HIS 531 531 ?   ?   ?   A . n 
A 1 532 HIS 532 532 ?   ?   ?   A . n 
A 1 533 HIS 533 533 ?   ?   ?   A . n 
A 1 534 HIS 534 534 ?   ?   ?   A . n 
A 1 535 HIS 535 535 ?   ?   ?   A . n 
A 1 536 HIS 536 536 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   SER 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   PHE 4   4   ?   ?   ?   B . n 
B 1 5   SER 5   5   ?   ?   ?   B . n 
B 1 6   THR 6   6   ?   ?   ?   B . n 
B 1 7   HIS 7   7   ?   ?   ?   B . n 
B 1 8   ASN 8   8   ?   ?   ?   B . n 
B 1 9   PHE 9   9   ?   ?   ?   B . n 
B 1 10  VAL 10  10  ?   ?   ?   B . n 
B 1 11  ALA 11  11  ?   ?   ?   B . n 
B 1 12  ILE 12  12  ?   ?   ?   B . n 
B 1 13  ALA 13  13  ?   ?   ?   B . n 
B 1 14  THR 14  14  ?   ?   ?   B . n 
B 1 15  PHE 15  15  ?   ?   ?   B . n 
B 1 16  VAL 16  16  ?   ?   ?   B . n 
B 1 17  CYS 17  17  ?   ?   ?   B . n 
B 1 18  TRP 18  18  ?   ?   ?   B . n 
B 1 19  PHE 19  19  ?   ?   ?   B . n 
B 1 20  CYS 20  20  ?   ?   ?   B . n 
B 1 21  CYS 21  21  ?   ?   ?   B . n 
B 1 22  LEU 22  22  ?   ?   ?   B . n 
B 1 23  ALA 23  23  ?   ?   ?   B . n 
B 1 24  THR 24  24  ?   ?   ?   B . n 
B 1 25  ALA 25  25  ?   ?   ?   B . n 
B 1 26  ALA 26  26  ?   ?   ?   B . n 
B 1 27  PRO 27  27  ?   ?   ?   B . n 
B 1 28  LEU 28  28  ?   ?   ?   B . n 
B 1 29  THR 29  29  ?   ?   ?   B . n 
B 1 30  SER 30  30  ?   ?   ?   B . n 
B 1 31  LYS 31  31  31  LYS LYS B . n 
B 1 32  ALA 32  32  32  ALA ALA B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  TYR 34  34  34  TYR TYR B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  LYS 37  37  37  LYS LYS B . n 
B 1 38  ARG 38  38  38  ARG ARG B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  ILE 42  42  42  ILE ILE B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  GLU 44  44  44  GLU GLU B . n 
B 1 45  ASP 45  45  45  ASP ASP B . n 
B 1 46  ALA 46  46  46  ALA ALA B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  LYS 49  49  49  LYS LYS B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  ALA 52  52  52  ALA ALA B . n 
B 1 53  LYS 53  53  53  LYS LYS B . n 
B 1 54  ILE 54  54  54  ILE ILE B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  LEU 56  56  56  LEU LEU B . n 
B 1 57  THR 57  57  57  THR THR B . n 
B 1 58  ASN 58  58  58  ASN ASN B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLU 60  60  60  GLU GLU B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  VAL 62  62  62  VAL VAL B . n 
B 1 63  LEU 63  63  63  LEU LEU B . n 
B 1 64  ASP 64  64  64  ASP ASP B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  ILE 67  67  67  ILE ILE B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  LYS 71  71  71  LYS LYS B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  LYS 73  73  73  LYS LYS B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  ILE 75  75  75  ILE ILE B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  ASP 77  77  77  ASP ASP B . n 
B 1 78  SER 78  78  78  SER SER B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  ASN 81  81  81  ASN ASN B . n 
B 1 82  GLN 82  82  82  GLN GLN B . n 
B 1 83  THR 83  83  83  THR THR B . n 
B 1 84  GLU 84  84  84  GLU GLU B . n 
B 1 85  TYR 85  85  85  TYR TYR B . n 
B 1 86  MET 86  86  86  MET MET B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  ALA 89  89  89  ALA ALA B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  TYR 92  92  92  TYR TYR B . n 
B 1 93  ARG 93  93  93  ARG ARG B . n 
B 1 94  SER 94  94  94  SER SER B . n 
B 1 95  LYS 95  95  95  LYS LYS B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  PHE 97  97  97  PHE PHE B . n 
B 1 98  ILE 98  98  98  ILE ILE B . n 
B 1 99  ASP 99  99  99  ASP ASP B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 PHE 102 102 102 PHE PHE B . n 
B 1 103 ALA 103 103 103 ALA ALA B . n 
B 1 104 TYR 104 104 104 TYR TYR B . n 
B 1 105 LYS 105 105 105 LYS LYS B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 GLN 108 108 108 GLN GLN B . n 
B 1 109 ASP 109 109 109 ASP ASP B . n 
B 1 110 MET 110 110 110 MET MET B . n 
B 1 111 PRO 111 111 111 PRO PRO B . n 
B 1 112 LYS 112 112 112 LYS LYS B . n 
B 1 113 GLY 113 113 113 GLY GLY B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 ALA 115 115 115 ALA ALA B . n 
B 1 116 LEU 116 116 116 LEU LEU B . n 
B 1 117 HIS 117 117 117 HIS HIS B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 HIS 119 119 119 HIS HIS B . n 
B 1 120 ASP 120 120 120 ASP ASP B . n 
B 1 121 THR 121 121 121 THR THR B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 ARG 125 125 125 ARG ARG B . n 
B 1 126 ILE 126 126 126 ILE ILE B . n 
B 1 127 ASP 127 127 127 ASP ASP B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 ILE 129 129 129 ILE ILE B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 ASN 132 132 132 ASN ASN B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 THR 134 134 134 THR THR B . n 
B 1 135 TYR 135 135 135 TYR TYR B . n 
B 1 136 ARG 136 136 136 ARG ARG B . n 
B 1 137 ASP 137 137 137 ASP ASP B . n 
B 1 138 HIS 138 138 138 HIS HIS B . n 
B 1 139 VAL 139 139 139 VAL VAL B . n 
B 1 140 TYR 140 140 140 TYR TYR B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 CYS 142 142 142 CYS CYS B . n 
B 1 143 MET 143 143 143 MET MET B . n 
B 1 144 ASP 144 144 144 ASP ASP B . n 
B 1 145 GLN 145 145 145 GLN GLN B . n 
B 1 146 ASP 146 146 146 ASP ASP B . n 
B 1 147 ASN 147 147 147 ASN ASN B . n 
B 1 148 PHE 148 148 148 PHE PHE B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 ARG 150 150 150 ARG ARG B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 THR 152 152 152 THR THR B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 SER 154 154 154 SER SER B . n 
B 1 155 GLY 155 155 155 GLY GLY B . n 
B 1 156 THR 156 156 156 THR THR B . n 
B 1 157 GLY 157 157 157 GLY GLY B . n 
B 1 158 PRO 158 158 158 PRO PRO B . n 
B 1 159 PRO 159 159 159 PRO PRO B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 ASN 161 161 161 ASN ASN B . n 
B 1 162 SER 162 162 162 SER SER B . n 
B 1 163 GLY 163 163 163 GLY GLY B . n 
B 1 164 CYS 164 164 164 CYS CYS B . n 
B 1 165 GLU 165 165 165 GLU GLU B . n 
B 1 166 TRP 166 166 166 TRP TRP B . n 
B 1 167 LYS 167 167 167 LYS LYS B . n 
B 1 168 LEU 168 168 168 LEU LEU B . n 
B 1 169 VAL 169 169 169 VAL VAL B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 THR 171 171 171 THR THR B . n 
B 1 172 GLU 172 172 172 GLU GLU B . n 
B 1 173 ARG 173 173 173 ARG ARG B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 ASN 175 175 175 ASN ASN B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 GLY 177 177 177 GLY GLY B . n 
B 1 178 ASP 178 178 178 ASP ASP B . n 
B 1 179 ILE 179 179 179 ILE ILE B . n 
B 1 180 ALA 180 180 180 ALA ALA B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 PHE 182 182 182 PHE PHE B . n 
B 1 183 ASP 183 183 183 ASP ASP B . n 
B 1 184 HIS 184 184 184 HIS HIS B . n 
B 1 185 TRP 185 185 185 TRP TRP B . n 
B 1 186 LEU 186 186 186 LEU LEU B . n 
B 1 187 LYS 187 187 187 LYS LYS B . n 
B 1 188 SER 188 188 188 SER SER B . n 
B 1 189 ASN 189 189 189 ASN ASN B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 THR 194 194 194 THR THR B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 ASP 196 196 196 ASP ASP B . n 
B 1 197 PRO 197 197 197 PRO PRO B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 VAL 199 199 199 VAL VAL B . n 
B 1 200 THR 200 200 200 THR THR B . n 
B 1 201 TYR 201 201 201 TYR TYR B . n 
B 1 202 PRO 202 202 202 PRO PRO B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 ASP 205 205 205 ASP ASP B . n 
B 1 206 LYS 206 206 206 LYS LYS B . n 
B 1 207 VAL 207 207 207 VAL VAL B . n 
B 1 208 TRP 208 208 208 TRP TRP B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 ARG 210 210 210 ARG ARG B . n 
B 1 211 PHE 211 211 211 PHE PHE B . n 
B 1 212 ASP 212 212 212 ASP ASP B . n 
B 1 213 LYS 213 213 213 LYS LYS B . n 
B 1 214 HIS 214 214 214 HIS HIS B . n 
B 1 215 PHE 215 215 215 PHE PHE B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 LEU 218 218 218 LEU LEU B . n 
B 1 219 ARG 219 219 219 ARG ARG B . n 
B 1 220 GLY 220 220 220 GLY GLY B . n 
B 1 221 ILE 221 221 221 ILE ILE B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 TYR 223 223 223 TYR TYR B . n 
B 1 224 HIS 224 224 224 HIS HIS B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 PRO 226 226 226 PRO PRO B . n 
B 1 227 ILE 227 227 227 ILE ILE B . n 
B 1 228 ARG 228 228 228 ARG ARG B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 ASP 230 230 230 ASP ASP B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 TYR 232 232 232 TYR TYR B . n 
B 1 233 ARG 233 233 233 ARG ARG B . n 
B 1 234 GLN 234 234 234 GLN GLN B . n 
B 1 235 ILE 235 235 235 ILE ILE B . n 
B 1 236 LEU 236 236 236 LEU LEU B . n 
B 1 237 GLU 237 237 237 GLU GLU B . n 
B 1 238 GLU 238 238 238 GLU GLU B . n 
B 1 239 PHE 239 239 239 PHE PHE B . n 
B 1 240 ARG 240 240 240 ARG ARG B . n 
B 1 241 SER 241 241 241 SER SER B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 ASN 243 243 243 ASN ASN B . n 
B 1 244 VAL 244 244 244 VAL VAL B . n 
B 1 245 GLN 245 245 245 GLN GLN B . n 
B 1 246 TYR 246 246 246 TYR TYR B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 GLU 248 248 248 GLU GLU B . n 
B 1 249 VAL 249 249 249 VAL VAL B . n 
B 1 250 ARG 250 250 250 ARG ARG B . n 
B 1 251 SER 251 251 251 SER SER B . n 
B 1 252 SER 252 252 252 SER SER B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 GLY 255 255 255 GLY GLY B . n 
B 1 256 PHE 256 256 256 PHE PHE B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 LEU 259 259 259 LEU LEU B . n 
B 1 260 ASP 260 260 260 ASP ASP B . n 
B 1 261 GLY 261 261 261 GLY GLY B . n 
B 1 262 THR 262 262 262 THR THR B . n 
B 1 263 VAL 263 263 263 VAL VAL B . n 
B 1 264 HIS 264 264 264 HIS HIS B . n 
B 1 265 ASP 265 265 265 ASP ASP B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 GLU 267 267 267 GLU GLU B . n 
B 1 268 PHE 268 268 268 PHE PHE B . n 
B 1 269 GLY 269 269 269 GLY GLY B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 ASN 271 271 271 ASN ASN B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 TYR 273 273 273 TYR TYR B . n 
B 1 274 LYS 274 274 274 LYS LYS B . n 
B 1 275 SER 275 275 275 SER SER B . n 
B 1 276 VAL 276 276 276 VAL VAL B . n 
B 1 277 THR 277 277 277 THR THR B . n 
B 1 278 GLU 278 278 278 GLU GLU B . n 
B 1 279 GLU 279 279 279 GLU GLU B . n 
B 1 280 PHE 280 280 280 PHE PHE B . n 
B 1 281 GLN 281 281 281 GLN GLN B . n 
B 1 282 ARG 282 282 282 ARG ARG B . n 
B 1 283 GLU 283 283 283 GLU GLU B . n 
B 1 284 TYR 284 284 284 TYR TYR B . n 
B 1 285 PRO 285 285 285 PRO PRO B . n 
B 1 286 ASP 286 286 286 ASP ASP B . n 
B 1 287 PHE 287 287 287 PHE PHE B . n 
B 1 288 ILE 288 288 288 ILE ILE B . n 
B 1 289 GLY 289 289 289 GLY GLY B . n 
B 1 290 ALA 290 290 290 ALA ALA B . n 
B 1 291 LYS 291 291 291 LYS LYS B . n 
B 1 292 ILE 292 292 292 ILE ILE B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 LEU 294 294 294 LEU LEU B . n 
B 1 295 SER 295 295 295 SER SER B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 PHE 299 299 299 PHE PHE B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 GLN 302 302 302 GLN GLN B . n 
B 1 303 GLU 303 303 303 GLU GLU B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 ILE 305 305 305 ILE ILE B . n 
B 1 306 LEU 306 306 306 LEU LEU B . n 
B 1 307 ASN 307 307 307 ASN ASN B . n 
B 1 308 GLU 308 308 308 GLU GLU B . n 
B 1 309 VAL 309 309 309 VAL VAL B . n 
B 1 310 LYS 310 310 310 LYS LYS B . n 
B 1 311 ILE 311 311 311 ILE ILE B . n 
B 1 312 ALA 312 312 312 ALA ALA B . n 
B 1 313 MET 313 313 313 MET MET B . n 
B 1 314 ASP 314 314 314 ASP ASP B . n 
B 1 315 LEU 315 315 315 LEU LEU B . n 
B 1 316 HIS 316 316 316 HIS HIS B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 LYS 318 318 318 LYS LYS B . n 
B 1 319 TYR 319 319 319 TYR TYR B . n 
B 1 320 PRO 320 320 320 PRO PRO B . n 
B 1 321 ASP 321 321 321 ASP ASP B . n 
B 1 322 PHE 322 322 322 PHE PHE B . n 
B 1 323 PHE 323 323 323 PHE PHE B . n 
B 1 324 LEU 324 324 324 LEU LEU B . n 
B 1 325 GLY 325 325 325 GLY GLY B . n 
B 1 326 TYR 326 326 326 TYR TYR B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 VAL 329 329 329 VAL VAL B . n 
B 1 330 GLY 330 330 330 GLY GLY B . n 
B 1 331 GLN 331 331 331 GLN GLN B . n 
B 1 332 GLU 332 332 332 GLU GLU B . n 
B 1 333 ASP 333 333 333 ASP ASP B . n 
B 1 334 PRO 334 334 334 PRO PRO B . n 
B 1 335 ASN 335 335 335 ASN ASN B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 SER 337 337 337 SER SER B . n 
B 1 338 LEU 338 338 338 LEU LEU B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 HIS 340 340 340 HIS HIS B . n 
B 1 341 TYR 341 341 341 TYR TYR B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 ALA 344 344 344 ALA ALA B . n 
B 1 345 LEU 345 345 345 LEU LEU B . n 
B 1 346 LEU 346 346 346 LEU LEU B . n 
B 1 347 TYR 347 347 347 TYR TYR B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 SER 349 349 349 SER SER B . n 
B 1 350 ILE 350 350 350 ILE ILE B . n 
B 1 351 GLN 351 351 351 GLN GLN B . n 
B 1 352 ASN 352 352 352 ASN ASN B . n 
B 1 353 PRO 353 353 353 PRO PRO B . n 
B 1 354 PRO 354 354 354 PRO PRO B . n 
B 1 355 TYR 355 355 355 TYR TYR B . n 
B 1 356 ARG 356 356 356 ARG ARG B . n 
B 1 357 LEU 357 357 357 LEU LEU B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 TYR 359 359 359 TYR TYR B . n 
B 1 360 PHE 360 360 360 PHE PHE B . n 
B 1 361 PHE 361 361 361 PHE PHE B . n 
B 1 362 HIS 362 362 362 HIS HIS B . n 
B 1 363 ALA 363 363 363 ALA ALA B . n 
B 1 364 ALA 364 364 364 ALA ALA B . n 
B 1 365 GLU 365 365 365 GLU GLU B . n 
B 1 366 THR 366 366 366 THR THR B . n 
B 1 367 ASN 367 367 367 ASN ASN B . n 
B 1 368 TRP 368 368 368 TRP TRP B . n 
B 1 369 GLN 369 369 369 GLN GLN B . n 
B 1 370 GLU 370 370 370 GLU GLU B . n 
B 1 371 THR 371 371 371 THR THR B . n 
B 1 372 GLU 372 372 372 GLU GLU B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 TYR 375 375 375 TYR TYR B . n 
B 1 376 ASN 376 376 376 ASN ASN B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 ALA 378 378 378 ALA ALA B . n 
B 1 379 ASP 379 379 379 ASP ASP B . n 
B 1 380 ALA 380 380 380 ALA ALA B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 LEU 383 383 383 LEU LEU B . n 
B 1 384 ASN 384 384 384 ASN ASN B . n 
B 1 385 THR 385 385 385 THR THR B . n 
B 1 386 THR 386 386 386 THR THR B . n 
B 1 387 ARG 387 387 387 ARG ARG B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 GLY 389 389 389 GLY GLY B . n 
B 1 390 HIS 390 390 390 HIS HIS B . n 
B 1 391 GLY 391 391 391 GLY GLY B . n 
B 1 392 PHE 392 392 392 PHE PHE B . n 
B 1 393 ALA 393 393 393 ALA ALA B . n 
B 1 394 LEU 394 394 394 LEU LEU B . n 
B 1 395 ILE 395 395 395 ILE ILE B . n 
B 1 396 LYS 396 396 396 LYS LYS B . n 
B 1 397 HIS 397 397 397 HIS HIS B . n 
B 1 398 PRO 398 398 398 PRO PRO B . n 
B 1 399 ARG 399 399 399 ARG ARG B . n 
B 1 400 PHE 400 400 400 PHE PHE B . n 
B 1 401 THR 401 401 401 THR THR B . n 
B 1 402 GLU 402 402 402 GLU GLU B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 ALA 404 404 404 ALA ALA B . n 
B 1 405 LYS 405 405 405 LYS LYS B . n 
B 1 406 GLU 406 406 406 GLU GLU B . n 
B 1 407 ASN 407 407 407 ASN ASN B . n 
B 1 408 GLY 408 408 408 GLY GLY B . n 
B 1 409 VAL 409 409 409 VAL VAL B . n 
B 1 410 ALA 410 410 410 ALA ALA B . n 
B 1 411 VAL 411 411 411 VAL VAL B . n 
B 1 412 GLU 412 412 412 GLU GLU B . n 
B 1 413 VAL 413 413 413 VAL VAL B . n 
B 1 414 ASN 414 414 414 ASN ASN B . n 
B 1 415 PRO 415 415 415 PRO PRO B . n 
B 1 416 ILE 416 416 416 ILE ILE B . n 
B 1 417 SER 417 417 417 SER SER B . n 
B 1 418 ASN 418 418 418 ASN ASN B . n 
B 1 419 GLN 419 419 419 GLN GLN B . n 
B 1 420 ILE 420 420 420 ILE ILE B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 GLY 422 422 422 GLY GLY B . n 
B 1 423 LEU 423 423 423 LEU LEU B . n 
B 1 424 VAL 424 424 424 VAL VAL B . n 
B 1 425 ARG 425 425 425 ARG ARG B . n 
B 1 426 ASP 426 426 426 ASP ASP B . n 
B 1 427 VAL 427 427 427 VAL VAL B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 ASN 429 429 429 ASN ASN B . n 
B 1 430 HIS 430 430 430 HIS HIS B . n 
B 1 431 ALA 431 431 431 ALA ALA B . n 
B 1 432 LEU 432 432 432 LEU LEU B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 PRO 434 434 434 PRO PRO B . n 
B 1 435 LEU 435 435 435 LEU LEU B . n 
B 1 436 ILE 436 436 436 ILE ILE B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 ASP 438 438 438 ASP ASP B . n 
B 1 439 ASP 439 439 439 ASP ASP B . n 
B 1 440 TYR 440 440 440 TYR TYR B . n 
B 1 441 PRO 441 441 441 PRO PRO B . n 
B 1 442 ILE 442 442 442 ILE ILE B . n 
B 1 443 VAL 443 443 443 VAL VAL B . n 
B 1 444 ILE 444 444 444 ILE ILE B . n 
B 1 445 SER 445 445 445 SER SER B . n 
B 1 446 SER 446 446 446 SER SER B . n 
B 1 447 ASP 447 447 447 ASP ASP B . n 
B 1 448 ASP 448 448 448 ASP ASP B . n 
B 1 449 PRO 449 449 449 PRO PRO B . n 
B 1 450 GLY 450 450 450 GLY GLY B . n 
B 1 451 ALA 451 451 451 ALA ALA B . n 
B 1 452 TRP 452 452 452 TRP TRP B . n 
B 1 453 GLU 453 453 453 GLU GLU B . n 
B 1 454 ALA 454 454 454 ALA ALA B . n 
B 1 455 SER 455 455 455 SER SER B . n 
B 1 456 PRO 456 456 456 PRO PRO B . n 
B 1 457 LEU 457 457 457 LEU LEU B . n 
B 1 458 SER 458 458 458 SER SER B . n 
B 1 459 HIS 459 459 459 HIS HIS B . n 
B 1 460 ASP 460 460 460 ASP ASP B . n 
B 1 461 PHE 461 461 461 PHE PHE B . n 
B 1 462 TYR 462 462 462 TYR TYR B . n 
B 1 463 VAL 463 463 463 VAL VAL B . n 
B 1 464 ALA 464 464 464 ALA ALA B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 MET 466 466 466 MET MET B . n 
B 1 467 ASP 467 467 467 ASP ASP B . n 
B 1 468 LEU 468 468 468 LEU LEU B . n 
B 1 469 CYS 469 469 469 CYS CYS B . n 
B 1 470 GLY 470 470 470 GLY GLY B . n 
B 1 471 ARG 471 471 471 ARG ARG B . n 
B 1 472 ASP 472 472 472 ASP ASP B . n 
B 1 473 THR 473 473 473 THR THR B . n 
B 1 474 ALA 474 474 474 ALA ALA B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 PHE 477 477 477 PHE PHE B . n 
B 1 478 LEU 478 478 478 LEU LEU B . n 
B 1 479 LYS 479 479 479 LYS LYS B . n 
B 1 480 GLN 480 480 480 GLN GLN B . n 
B 1 481 LEU 481 481 481 LEU LEU B . n 
B 1 482 ALA 482 482 482 ALA ALA B . n 
B 1 483 LEU 483 483 483 LEU LEU B . n 
B 1 484 ASN 484 484 484 ASN ASN B . n 
B 1 485 SER 485 485 485 SER SER B . n 
B 1 486 ILE 486 486 486 ILE ILE B . n 
B 1 487 ARG 487 487 487 ARG ARG B . n 
B 1 488 TYR 488 488 488 TYR TYR B . n 
B 1 489 SER 489 489 489 SER SER B . n 
B 1 490 ALA 490 490 490 ALA ALA B . n 
B 1 491 MET 491 491 491 MET MET B . n 
B 1 492 SER 492 492 492 SER SER B . n 
B 1 493 ASP 493 493 493 ASP ASP B . n 
B 1 494 THR 494 494 494 THR THR B . n 
B 1 495 GLU 495 495 495 GLU GLU B . n 
B 1 496 LYS 496 496 496 LYS LYS B . n 
B 1 497 VAL 497 497 497 VAL VAL B . n 
B 1 498 ALA 498 498 498 ALA ALA B . n 
B 1 499 ALA 499 499 499 ALA ALA B . n 
B 1 500 LYS 500 500 500 LYS LYS B . n 
B 1 501 ALA 501 501 501 ALA ALA B . n 
B 1 502 LYS 502 502 502 LYS LYS B . n 
B 1 503 TRP 503 503 503 TRP TRP B . n 
B 1 504 THR 504 504 504 THR THR B . n 
B 1 505 THR 505 505 505 THR THR B . n 
B 1 506 GLN 506 506 506 GLN GLN B . n 
B 1 507 TRP 507 507 507 TRP TRP B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 LYS 509 509 509 LYS LYS B . n 
B 1 510 PHE 510 510 510 PHE PHE B . n 
B 1 511 VAL 511 511 511 VAL VAL B . n 
B 1 512 LYS 512 512 512 LYS LYS B . n 
B 1 513 THR 513 513 513 THR THR B . n 
B 1 514 SER 514 514 514 SER SER B . n 
B 1 515 VAL 515 515 515 VAL VAL B . n 
B 1 516 GLU 516 516 516 GLU GLU B . n 
B 1 517 GLY 517 517 517 GLY GLY B . n 
B 1 518 LEU 518 518 518 LEU LEU B . n 
B 1 519 LYS 519 519 519 LYS LYS B . n 
B 1 520 PRO 520 520 520 PRO PRO B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 ILE 522 522 ?   ?   ?   B . n 
B 1 523 ASN 523 523 ?   ?   ?   B . n 
B 1 524 ASP 524 524 ?   ?   ?   B . n 
B 1 525 ARG 525 525 ?   ?   ?   B . n 
B 1 526 SER 526 526 ?   ?   ?   B . n 
B 1 527 HIS 527 527 ?   ?   ?   B . n 
B 1 528 HIS 528 528 ?   ?   ?   B . n 
B 1 529 HIS 529 529 ?   ?   ?   B . n 
B 1 530 HIS 530 530 ?   ?   ?   B . n 
B 1 531 HIS 531 531 ?   ?   ?   B . n 
B 1 532 HIS 532 532 ?   ?   ?   B . n 
B 1 533 HIS 533 533 ?   ?   ?   B . n 
B 1 534 HIS 534 534 ?   ?   ?   B . n 
B 1 535 HIS 535 535 ?   ?   ?   B . n 
B 1 536 HIS 536 536 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 NAG 1 601 925  NAG NAG A . 
D 2 NAG 1 602 1025 NAG NAG A . 
E 2 NAG 1 603 1026 NAG NAG A . 
F 3 ZN  1 604 2    ZN  ZN  A . 
G 2 NAG 1 601 525  NAG NAG B . 
H 2 NAG 1 602 625  NAG NAG B . 
I 2 NAG 1 603 725  NAG NAG B . 
J 3 ZN  1 604 1    ZN  ZN  B . 
K 4 HOH 1 701 3    HOH HOH B . 
K 4 HOH 2 702 2    HOH HOH B . 
K 4 HOH 3 703 1    HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A LYS 105 ? CG ? A LYS 105 CG 
2 1 Y 1 A LYS 105 ? CD ? A LYS 105 CD 
3 1 Y 1 A LYS 105 ? CE ? A LYS 105 CE 
4 1 Y 1 A LYS 105 ? NZ ? A LYS 105 NZ 
5 1 Y 1 B LYS 105 ? CG ? B LYS 105 CG 
6 1 Y 1 B LYS 105 ? CD ? B LYS 105 CD 
7 1 Y 1 B LYS 105 ? CE ? B LYS 105 CE 
8 1 Y 1 B LYS 105 ? NZ ? B LYS 105 NZ 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? 1.21.2_5419 ? 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000  ? ? ? .           ? 2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? SCALEPACK ? ? ? .           ? 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? ? .           ? 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NTI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     69.444 
_cell.length_a_esd                 ? 
_cell.length_b                     109.268 
_cell.length_b_esd                 ? 
_cell.length_c                     173.275 
_cell.length_c_esd                 ? 
_cell.volume                       1314811.912 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NTI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NTI 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.68 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          54.06 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Sodium acetate trihydrate pH 4.5, 25% w/v Polyethylene glycol 3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-06-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 22-ID' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   22-ID 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9NTI 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.99 
_reflns.d_resolution_low                               46.21 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     519122 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.33 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                19.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.121 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.985 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.99 
_reflns_shell.d_res_low                                     3.10 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.0 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2644 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.630 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.513 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NTI 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.00 
_refine.ls_d_res_low                             46.21 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     50431 
_refine.ls_number_reflns_R_free                  3737 
_refine.ls_number_reflns_R_work                  46694 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.02 
_refine.ls_percent_reflns_R_free                 7.41 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2202 
_refine.ls_R_factor_R_free                       0.2735 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2160 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 31.4145 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.5525 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.00 
_refine_hist.d_res_low                        46.21 
_refine_hist.number_atoms_solvent             3 
_refine_hist.number_atoms_total               8038 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        7943 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         92 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0025  ? 8231  ? f_bond_d           ? ? ? 
'X-RAY DIFFRACTION' ? 0.6765  ? 11182 ? f_angle_d          ? ? ? 
'X-RAY DIFFRACTION' ? 0.0890  ? 1247  ? f_chiral_restr     ? ? ? 
'X-RAY DIFFRACTION' ? 0.0041  ? 1432  ? f_plane_restr      ? ? ? 
'X-RAY DIFFRACTION' ? 13.0927 ? 3116  ? f_dihedral_angle_d ? ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.00 3.04  . . 115 1471 84.63  . . . . 0.4527 . . . . . . . . . . . . . . . 0.5546 
'X-RAY DIFFRACTION' 3.04 3.08  . . 140 1709 97.62  . . . . 0.4257 . . . . . . . . . . . . . . . 0.4147 
'X-RAY DIFFRACTION' 3.08 3.12  . . 133 1705 98.08  . . . . 0.3998 . . . . . . . . . . . . . . . 0.4995 
'X-RAY DIFFRACTION' 3.12 3.17  . . 144 1748 98.70  . . . . 0.3923 . . . . . . . . . . . . . . . 0.4118 
'X-RAY DIFFRACTION' 3.17 3.21  . . 137 1731 98.89  . . . . 0.3425 . . . . . . . . . . . . . . . 0.3853 
'X-RAY DIFFRACTION' 3.21 3.26  . . 140 1699 99.51  . . . . 0.3155 . . . . . . . . . . . . . . . 0.3786 
'X-RAY DIFFRACTION' 3.26 3.32  . . 146 1807 99.95  . . . . 0.3058 . . . . . . . . . . . . . . . 0.3840 
'X-RAY DIFFRACTION' 3.32 3.37  . . 132 1654 99.72  . . . . 0.3057 . . . . . . . . . . . . . . . 0.3573 
'X-RAY DIFFRACTION' 3.37 3.44  . . 143 1779 99.53  . . . . 0.3009 . . . . . . . . . . . . . . . 0.3738 
'X-RAY DIFFRACTION' 3.44 3.50  . . 135 1754 100.00 . . . . 0.2929 . . . . . . . . . . . . . . . 0.3202 
'X-RAY DIFFRACTION' 3.50 3.57  . . 135 1713 99.52  . . . . 0.2672 . . . . . . . . . . . . . . . 0.3194 
'X-RAY DIFFRACTION' 3.57 3.65  . . 143 1772 99.84  . . . . 0.2645 . . . . . . . . . . . . . . . 0.3417 
'X-RAY DIFFRACTION' 3.65 3.74  . . 140 1740 99.95  . . . . 0.2407 . . . . . . . . . . . . . . . 0.2367 
'X-RAY DIFFRACTION' 3.74 3.83  . . 144 1750 99.89  . . . . 0.2192 . . . . . . . . . . . . . . . 0.3036 
'X-RAY DIFFRACTION' 3.83 3.93  . . 144 1749 99.58  . . . . 0.2085 . . . . . . . . . . . . . . . 0.2764 
'X-RAY DIFFRACTION' 3.93 4.05  . . 141 1743 99.95  . . . . 0.1965 . . . . . . . . . . . . . . . 0.2618 
'X-RAY DIFFRACTION' 4.05 4.18  . . 135 1728 99.89  . . . . 0.1904 . . . . . . . . . . . . . . . 0.2754 
'X-RAY DIFFRACTION' 4.18 4.33  . . 145 1778 100.00 . . . . 0.1756 . . . . . . . . . . . . . . . 0.2889 
'X-RAY DIFFRACTION' 4.33 4.50  . . 138 1712 99.95  . . . . 0.1705 . . . . . . . . . . . . . . . 0.2337 
'X-RAY DIFFRACTION' 4.50 4.71  . . 135 1739 99.89  . . . . 0.1669 . . . . . . . . . . . . . . . 0.2039 
'X-RAY DIFFRACTION' 4.71 4.95  . . 138 1777 99.90  . . . . 0.1595 . . . . . . . . . . . . . . . 0.2171 
'X-RAY DIFFRACTION' 4.95 5.26  . . 135 1727 100.00 . . . . 0.1742 . . . . . . . . . . . . . . . 0.2205 
'X-RAY DIFFRACTION' 5.26 5.67  . . 142 1742 99.95  . . . . 0.1886 . . . . . . . . . . . . . . . 0.3175 
'X-RAY DIFFRACTION' 5.67 6.24  . . 133 1741 99.84  . . . . 0.1951 . . . . . . . . . . . . . . . 0.2726 
'X-RAY DIFFRACTION' 6.24 7.14  . . 146 1752 99.95  . . . . 0.1943 . . . . . . . . . . . . . . . 0.2485 
'X-RAY DIFFRACTION' 7.14 8.98  . . 133 1745 100.00 . . . . 0.1743 . . . . . . . . . . . . . . . 0.2219 
'X-RAY DIFFRACTION' 8.98 46.21 . . 145 1729 99.00  . . . . 0.1668 . . . . . . . . . . . . . . . 0.1817 
# 
_struct.entry_id                     9NTI 
_struct.title                        'Chimeric Adenosine deaminase growth factor (ADGF) apoenzyme' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NTI 
_struct_keywords.text            
'Chimeric Adenosine deaminase growth factor (ADGF) apoenzyme; Hydrolase; Adenosine deaminase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 3 ? 
G N N 2 ? 
H N N 2 ? 
I N N 2 ? 
J N N 3 ? 
K N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP AGSA_APLCA P15287 ? 1 
;MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRL
NQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHD
;
1   
2 PDB 9NTI       9NTI   ? 1 ? 121 
3 UNP AGSA_APLCA P15287 ? 1 
;GFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYPDFFLGYDLVGQEDP
NFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRFTELAKENGVAVEVN
PISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQLALNSIRYSAMSDT
EKVAAKAKWTTQWDKFVKTSVEGLKPHINDRS
;
254 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NTI A 1   ? 120 ? P15287 1   ? 120 ? 1   120 
2 2 9NTI A 121 ? 254 ? 9NTI   121 ? 254 ? 121 254 
3 3 9NTI A 255 ? 526 ? P15287 254 ? 525 ? 255 526 
4 1 9NTI B 1   ? 120 ? P15287 1   ? 120 ? 1   120 
5 2 9NTI B 121 ? 254 ? 9NTI   121 ? 254 ? 121 254 
6 3 9NTI B 255 ? 526 ? P15287 254 ? 525 ? 255 526 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9NTI HIS A 527 ? UNP P15287 ? ? 'expression tag' 527 1  
3 9NTI HIS A 528 ? UNP P15287 ? ? 'expression tag' 528 2  
3 9NTI HIS A 529 ? UNP P15287 ? ? 'expression tag' 529 3  
3 9NTI HIS A 530 ? UNP P15287 ? ? 'expression tag' 530 4  
3 9NTI HIS A 531 ? UNP P15287 ? ? 'expression tag' 531 5  
3 9NTI HIS A 532 ? UNP P15287 ? ? 'expression tag' 532 6  
3 9NTI HIS A 533 ? UNP P15287 ? ? 'expression tag' 533 7  
3 9NTI HIS A 534 ? UNP P15287 ? ? 'expression tag' 534 8  
3 9NTI HIS A 535 ? UNP P15287 ? ? 'expression tag' 535 9  
3 9NTI HIS A 536 ? UNP P15287 ? ? 'expression tag' 536 10 
6 9NTI HIS B 527 ? UNP P15287 ? ? 'expression tag' 527 11 
6 9NTI HIS B 528 ? UNP P15287 ? ? 'expression tag' 528 12 
6 9NTI HIS B 529 ? UNP P15287 ? ? 'expression tag' 529 13 
6 9NTI HIS B 530 ? UNP P15287 ? ? 'expression tag' 530 14 
6 9NTI HIS B 531 ? UNP P15287 ? ? 'expression tag' 531 15 
6 9NTI HIS B 532 ? UNP P15287 ? ? 'expression tag' 532 16 
6 9NTI HIS B 533 ? UNP P15287 ? ? 'expression tag' 533 17 
6 9NTI HIS B 534 ? UNP P15287 ? ? 'expression tag' 534 18 
6 9NTI HIS B 535 ? UNP P15287 ? ? 'expression tag' 535 19 
6 9NTI HIS B 536 ? UNP P15287 ? ? 'expression tag' 536 20 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 7980  ? 
1 MORE         -81   ? 
1 'SSA (A^2)'  38670 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 29  ? SER A 47  ? THR A 29  SER A 47  1 ? 19 
HELX_P HELX_P2  AA2 THR A 57  ? LEU A 80  ? THR A 57  LEU A 80  1 ? 24 
HELX_P HELX_P3  AA3 TYR A 85  ? ALA A 89  ? TYR A 85  ALA A 89  5 ? 5  
HELX_P HELX_P4  AA4 SER A 90  ? ASP A 99  ? SER A 90  ASP A 99  1 ? 10 
HELX_P HELX_P5  AA5 THR A 101 ? ASP A 109 ? THR A 101 ASP A 109 1 ? 9  
HELX_P HELX_P6  AA6 THR A 121 ? SER A 123 ? THR A 121 SER A 123 5 ? 3  
HELX_P HELX_P7  AA7 ARG A 125 ? ASN A 132 ? ARG A 125 ASN A 132 1 ? 8  
HELX_P HELX_P8  AA8 ALA A 133 ? ARG A 136 ? ALA A 133 ARG A 136 5 ? 4  
HELX_P HELX_P9  AA9 VAL A 169 ? ASN A 175 ? VAL A 169 ASN A 175 1 ? 7  
HELX_P HELX_P10 AB1 ASP A 178 ? SER A 191 ? ASP A 178 SER A 191 1 ? 14 
HELX_P HELX_P11 AB2 ASP A 196 ? TYR A 201 ? ASP A 196 TYR A 201 1 ? 6  
HELX_P HELX_P12 AB3 SER A 203 ? TYR A 223 ? SER A 203 TYR A 223 1 ? 21 
HELX_P HELX_P13 AB4 HIS A 224 ? ASP A 242 ? HIS A 224 ASP A 242 1 ? 19 
HELX_P HELX_P14 AB5 ASP A 265 ? TYR A 284 ? ASP A 265 TYR A 284 1 ? 20 
HELX_P HELX_P15 AB6 SER A 301 ? TYR A 319 ? SER A 301 TYR A 319 1 ? 19 
HELX_P HELX_P16 AB7 LEU A 338 ? HIS A 340 ? LEU A 338 HIS A 340 5 ? 3  
HELX_P HELX_P17 AB8 TYR A 341 ? LEU A 346 ? TYR A 341 LEU A 346 1 ? 6  
HELX_P HELX_P18 AB9 LEU A 346 ? GLN A 351 ? LEU A 346 GLN A 351 1 ? 6  
HELX_P HELX_P19 AC1 THR A 371 ? LEU A 383 ? THR A 371 LEU A 383 1 ? 13 
HELX_P HELX_P20 AC2 HIS A 397 ? GLY A 408 ? HIS A 397 GLY A 408 1 ? 12 
HELX_P HELX_P21 AC3 ASN A 414 ? LEU A 421 ? ASN A 414 LEU A 421 1 ? 8  
HELX_P HELX_P22 AC4 ASP A 426 ? HIS A 430 ? ASP A 426 HIS A 430 5 ? 5  
HELX_P HELX_P23 AC5 LEU A 432 ? ALA A 437 ? LEU A 432 ALA A 437 1 ? 6  
HELX_P HELX_P24 AC6 LEU A 457 ? LEU A 468 ? LEU A 457 LEU A 468 1 ? 12 
HELX_P HELX_P25 AC7 ALA A 474 ? TYR A 488 ? ALA A 474 TYR A 488 1 ? 15 
HELX_P HELX_P26 AC8 SER A 492 ? LYS A 519 ? SER A 492 LYS A 519 1 ? 28 
HELX_P HELX_P27 AC9 ALA B 32  ? SER B 47  ? ALA B 32  SER B 47  1 ? 16 
HELX_P HELX_P28 AD1 THR B 57  ? ASN B 81  ? THR B 57  ASN B 81  1 ? 25 
HELX_P HELX_P29 AD2 TYR B 85  ? ALA B 89  ? TYR B 85  ALA B 89  5 ? 5  
HELX_P HELX_P30 AD3 SER B 90  ? ASP B 99  ? SER B 90  ASP B 99  1 ? 10 
HELX_P HELX_P31 AD4 THR B 101 ? ASP B 109 ? THR B 101 ASP B 109 1 ? 9  
HELX_P HELX_P32 AD5 THR B 121 ? SER B 123 ? THR B 121 SER B 123 5 ? 3  
HELX_P HELX_P33 AD6 ARG B 125 ? ASN B 132 ? ARG B 125 ASN B 132 1 ? 8  
HELX_P HELX_P34 AD7 ALA B 133 ? ARG B 136 ? ALA B 133 ARG B 136 5 ? 4  
HELX_P HELX_P35 AD8 VAL B 169 ? ASN B 175 ? VAL B 169 ASN B 175 1 ? 7  
HELX_P HELX_P36 AD9 ASP B 178 ? ASN B 189 ? ASP B 178 ASN B 189 1 ? 12 
HELX_P HELX_P37 AE1 ASP B 196 ? TYR B 201 ? ASP B 196 TYR B 201 1 ? 6  
HELX_P HELX_P38 AE2 SER B 203 ? TYR B 223 ? SER B 203 TYR B 223 1 ? 21 
HELX_P HELX_P39 AE3 HIS B 224 ? SER B 241 ? HIS B 224 SER B 241 1 ? 18 
HELX_P HELX_P40 AE4 ASP B 265 ? TYR B 284 ? ASP B 265 TYR B 284 1 ? 20 
HELX_P HELX_P41 AE5 SER B 301 ? TYR B 319 ? SER B 301 TYR B 319 1 ? 19 
HELX_P HELX_P42 AE6 TYR B 341 ? LEU B 346 ? TYR B 341 LEU B 346 1 ? 6  
HELX_P HELX_P43 AE7 TYR B 375 ? LEU B 383 ? TYR B 375 LEU B 383 1 ? 9  
HELX_P HELX_P44 AE8 HIS B 397 ? GLY B 408 ? HIS B 397 GLY B 408 1 ? 12 
HELX_P HELX_P45 AE9 ASN B 414 ? LEU B 421 ? ASN B 414 LEU B 421 1 ? 8  
HELX_P HELX_P46 AF1 ASP B 426 ? HIS B 430 ? ASP B 426 HIS B 430 5 ? 5  
HELX_P HELX_P47 AF2 LEU B 432 ? ALA B 437 ? LEU B 432 ALA B 437 1 ? 6  
HELX_P HELX_P48 AF3 LEU B 457 ? LEU B 468 ? LEU B 457 LEU B 468 1 ? 12 
HELX_P HELX_P49 AF4 ALA B 474 ? TYR B 488 ? ALA B 474 TYR B 488 1 ? 15 
HELX_P HELX_P50 AF5 SER B 492 ? LYS B 519 ? SER B 492 LYS B 519 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?   ? A CYS 142 SG  ? ? ? 1_555 A CYS 164 SG ? ? A CYS 142 A CYS 164 1_555 ? ? ? ? ? ? ? 2.026 ? ?               
disulf2 disulf ?   ? B CYS 142 SG  ? ? ? 1_555 B CYS 164 SG ? ? B CYS 142 B CYS 164 1_555 ? ? ? ? ? ? ? 2.027 ? ?               
covale1 covale one ? A ASN 132 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 132 A NAG 603 1_555 ? ? ? ? ? ? ? 1.459 ? N-Glycosylation 
covale2 covale one ? B ASN 81  ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 81  B NAG 601 1_555 ? ? ? ? ? ? ? 1.471 ? N-Glycosylation 
covale3 covale one ? B ASN 132 ND2 ? ? ? 1_555 I NAG .   C1 ? ? B ASN 132 B NAG 603 1_555 ? ? ? ? ? ? ? 1.469 ? N-Glycosylation 
covale4 covale one ? B ASN 189 ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 189 B NAG 602 1_555 ? ? ? ? ? ? ? 1.477 ? N-Glycosylation 
metalc1 metalc ?   ? A HIS 117 NE2 ? ? ? 1_555 F ZN  .   ZN ? ? A HIS 117 A ZN  604 1_555 ? ? ? ? ? ? ? 2.295 ? ?               
metalc2 metalc ?   ? A HIS 119 NE2 ? ? ? 1_555 F ZN  .   ZN ? ? A HIS 119 A ZN  604 1_555 ? ? ? ? ? ? ? 2.295 ? ?               
metalc3 metalc ?   ? A HIS 362 NE2 ? ? ? 1_555 F ZN  .   ZN ? ? A HIS 362 A ZN  604 1_555 ? ? ? ? ? ? ? 2.295 ? ?               
metalc4 metalc ?   ? A ASP 447 OD1 ? ? ? 1_555 F ZN  .   ZN ? ? A ASP 447 A ZN  604 1_555 ? ? ? ? ? ? ? 2.670 ? ?               
metalc5 metalc ?   ? B HIS 117 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? B HIS 117 B ZN  604 1_555 ? ? ? ? ? ? ? 2.302 ? ?               
metalc6 metalc ?   ? B HIS 119 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? B HIS 119 B ZN  604 1_555 ? ? ? ? ? ? ? 2.301 ? ?               
metalc7 metalc ?   ? B HIS 362 NE2 ? ? ? 1_555 J ZN  .   ZN ? ? B HIS 362 B ZN  604 1_555 ? ? ? ? ? ? ? 2.301 ? ?               
metalc8 metalc ?   ? B ASP 447 OD1 ? ? ? 1_555 J ZN  .   ZN ? ? B ASP 447 B ZN  604 1_555 ? ? ? ? ? ? ? 2.416 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 NE2 ? A HIS 119 ? A HIS 119 ? 1_555 118.0 ? 
2  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 NE2 ? A HIS 362 ? A HIS 362 ? 1_555 98.9  ? 
3  NE2 ? A HIS 119 ? A HIS 119 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 NE2 ? A HIS 362 ? A HIS 362 ? 1_555 107.5 ? 
4  NE2 ? A HIS 117 ? A HIS 117 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 73.3  ? 
5  NE2 ? A HIS 119 ? A HIS 119 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 76.9  ? 
6  NE2 ? A HIS 362 ? A HIS 362 ? 1_555 ZN ? F ZN . ? A ZN 604 ? 1_555 OD1 ? A ASP 447 ? A ASP 447 ? 1_555 172.2 ? 
7  NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 96.2  ? 
8  NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 90.3  ? 
9  NE2 ? B HIS 119 ? B HIS 119 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 96.8  ? 
10 NE2 ? B HIS 117 ? B HIS 117 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 72.4  ? 
11 NE2 ? B HIS 119 ? B HIS 119 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 95.0  ? 
12 NE2 ? B HIS 362 ? B HIS 362 ? 1_555 ZN ? J ZN . ? B ZN 604 ? 1_555 OD1 ? B ASP 447 ? B ASP 447 ? 1_555 159.9 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG E .   ? ASN A 132 ? NAG A 603 ? 1_555 ASN A 132 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG G .   ? ASN B 81  ? NAG B 601 ? 1_555 ASN B 81  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG H .   ? ASN B 189 ? NAG B 602 ? 1_555 ASN B 189 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG I .   ? ASN B 132 ? NAG B 603 ? 1_555 ASN B 132 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 142 ? CYS A 164 ? CYS A 142 ? 1_555 CYS A 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6 CYS B 142 ? CYS B 164 ? CYS B 142 ? 1_555 CYS B 164 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 ASN 352 A . ? ASN 352 A PRO 353 A ? PRO 353 A 1 -0.97 
2 ASN 352 B . ? ASN 352 B PRO 353 B ? PRO 353 B 1 -7.24 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLY A 114 ? HIS A 119 ? GLY A 114 HIS A 119 
AA1 2 TYR A 246 ? SER A 251 ? TYR A 246 SER A 251 
AA1 3 GLY A 289 ? LEU A 297 ? GLY A 289 LEU A 297 
AA1 4 PHE A 323 ? VAL A 329 ? PHE A 323 VAL A 329 
AA2 1 VAL A 149 ? VAL A 153 ? VAL A 149 VAL A 153 
AA2 2 VAL A 139 ? MET A 143 ? VAL A 139 MET A 143 
AA2 3 LYS A 167 ? LEU A 168 ? LYS A 167 LEU A 168 
AA3 1 HIS A 362 ? ALA A 363 ? HIS A 362 ALA A 363 
AA3 2 ARG A 387 ? HIS A 390 ? ARG A 387 HIS A 390 
AA3 3 ALA A 410 ? VAL A 413 ? ALA A 410 VAL A 413 
AA3 4 ILE A 442 ? ILE A 444 ? ILE A 442 ILE A 444 
AA4 1 GLY B 114 ? HIS B 119 ? GLY B 114 HIS B 119 
AA4 2 TYR B 246 ? SER B 251 ? TYR B 246 SER B 251 
AA4 3 GLY B 289 ? LEU B 297 ? GLY B 289 LEU B 297 
AA4 4 PHE B 323 ? VAL B 329 ? PHE B 323 VAL B 329 
AA5 1 VAL B 149 ? VAL B 153 ? VAL B 149 VAL B 153 
AA5 2 VAL B 139 ? MET B 143 ? VAL B 139 MET B 143 
AA5 3 LYS B 167 ? LEU B 168 ? LYS B 167 LEU B 168 
AA6 1 HIS B 362 ? ALA B 363 ? HIS B 362 ALA B 363 
AA6 2 ARG B 387 ? HIS B 390 ? ARG B 387 HIS B 390 
AA6 3 ALA B 410 ? VAL B 413 ? ALA B 410 VAL B 413 
AA6 4 ILE B 442 ? ILE B 444 ? ILE B 442 ILE B 444 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA A 115 ? N ALA A 115 O TYR A 246 ? O TYR A 246 
AA1 2 3 N VAL A 249 ? N VAL A 249 O ILE A 293 ? O ILE A 293 
AA1 3 4 N GLY A 296 ? N GLY A 296 O VAL A 329 ? O VAL A 329 
AA2 1 2 O ARG A 150 ? O ARG A 150 N CYS A 142 ? N CYS A 142 
AA2 2 3 N MET A 141 ? N MET A 141 O LYS A 167 ? O LYS A 167 
AA3 1 2 N ALA A 363 ? N ALA A 363 O GLY A 389 ? O GLY A 389 
AA3 2 3 N VAL A 388 ? N VAL A 388 O GLU A 412 ? O GLU A 412 
AA3 3 4 N VAL A 413 ? N VAL A 413 O VAL A 443 ? O VAL A 443 
AA4 1 2 N ALA B 115 ? N ALA B 115 O TYR B 246 ? O TYR B 246 
AA4 2 3 N SER B 251 ? N SER B 251 O ILE B 293 ? O ILE B 293 
AA4 3 4 N GLY B 296 ? N GLY B 296 O VAL B 329 ? O VAL B 329 
AA5 1 2 O THR B 152 ? O THR B 152 N TYR B 140 ? N TYR B 140 
AA5 2 3 N MET B 141 ? N MET B 141 O LYS B 167 ? O LYS B 167 
AA6 1 2 N ALA B 363 ? N ALA B 363 O GLY B 389 ? O GLY B 389 
AA6 2 3 N VAL B 388 ? N VAL B 388 O ALA B 410 ? O ALA B 410 
AA6 3 4 N VAL B 413 ? N VAL B 413 O VAL B 443 ? O VAL B 443 
# 
_pdbx_entry_details.entry_id                   9NTI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 ND2 B ASN 81  ? ? O1 B NAG 601 ? ? 1.21 
2 1 ND2 B ASN 132 ? ? O1 B NAG 603 ? ? 1.75 
3 1 CG  B ASN 81  ? ? O1 B NAG 601 ? ? 1.86 
4 1 ND2 B ASN 189 ? ? O5 B NAG 602 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 122 ? ? -142.85 24.84  
2  1 THR A 156 ? ? -99.43  35.50  
3  1 SER A 176 ? ? -93.88  -61.40 
4  1 LEU A 253 ? ? 72.99   -8.36  
5  1 HIS A 390 ? ? 67.38   -70.23 
6  1 ASP A 447 ? ? -120.53 -59.02 
7  1 ALA A 474 ? ? -120.71 -64.89 
8  1 ALA B 122 ? ? -144.26 24.92  
9  1 LEU B 253 ? ? 70.08   -4.63  
10 1 HIS B 390 ? ? 66.46   -71.30 
11 1 ALA B 474 ? ? -121.05 -65.52 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A SER 2   ? A SER 2   
3  1 Y 1 A SER 3   ? A SER 3   
4  1 Y 1 A PHE 4   ? A PHE 4   
5  1 Y 1 A SER 5   ? A SER 5   
6  1 Y 1 A THR 6   ? A THR 6   
7  1 Y 1 A HIS 7   ? A HIS 7   
8  1 Y 1 A ASN 8   ? A ASN 8   
9  1 Y 1 A PHE 9   ? A PHE 9   
10 1 Y 1 A VAL 10  ? A VAL 10  
11 1 Y 1 A ALA 11  ? A ALA 11  
12 1 Y 1 A ILE 12  ? A ILE 12  
13 1 Y 1 A ALA 13  ? A ALA 13  
14 1 Y 1 A THR 14  ? A THR 14  
15 1 Y 1 A PHE 15  ? A PHE 15  
16 1 Y 1 A VAL 16  ? A VAL 16  
17 1 Y 1 A CYS 17  ? A CYS 17  
18 1 Y 1 A TRP 18  ? A TRP 18  
19 1 Y 1 A PHE 19  ? A PHE 19  
20 1 Y 1 A CYS 20  ? A CYS 20  
21 1 Y 1 A CYS 21  ? A CYS 21  
22 1 Y 1 A LEU 22  ? A LEU 22  
23 1 Y 1 A ALA 23  ? A ALA 23  
24 1 Y 1 A THR 24  ? A THR 24  
25 1 Y 1 A ALA 25  ? A ALA 25  
26 1 Y 1 A ALA 26  ? A ALA 26  
27 1 Y 1 A PRO 27  ? A PRO 27  
28 1 Y 1 A LEU 28  ? A LEU 28  
29 1 Y 1 A ILE 522 ? A ILE 522 
30 1 Y 1 A ASN 523 ? A ASN 523 
31 1 Y 1 A ASP 524 ? A ASP 524 
32 1 Y 1 A ARG 525 ? A ARG 525 
33 1 Y 1 A SER 526 ? A SER 526 
34 1 Y 1 A HIS 527 ? A HIS 527 
35 1 Y 1 A HIS 528 ? A HIS 528 
36 1 Y 1 A HIS 529 ? A HIS 529 
37 1 Y 1 A HIS 530 ? A HIS 530 
38 1 Y 1 A HIS 531 ? A HIS 531 
39 1 Y 1 A HIS 532 ? A HIS 532 
40 1 Y 1 A HIS 533 ? A HIS 533 
41 1 Y 1 A HIS 534 ? A HIS 534 
42 1 Y 1 A HIS 535 ? A HIS 535 
43 1 Y 1 A HIS 536 ? A HIS 536 
44 1 Y 1 B MET 1   ? B MET 1   
45 1 Y 1 B SER 2   ? B SER 2   
46 1 Y 1 B SER 3   ? B SER 3   
47 1 Y 1 B PHE 4   ? B PHE 4   
48 1 Y 1 B SER 5   ? B SER 5   
49 1 Y 1 B THR 6   ? B THR 6   
50 1 Y 1 B HIS 7   ? B HIS 7   
51 1 Y 1 B ASN 8   ? B ASN 8   
52 1 Y 1 B PHE 9   ? B PHE 9   
53 1 Y 1 B VAL 10  ? B VAL 10  
54 1 Y 1 B ALA 11  ? B ALA 11  
55 1 Y 1 B ILE 12  ? B ILE 12  
56 1 Y 1 B ALA 13  ? B ALA 13  
57 1 Y 1 B THR 14  ? B THR 14  
58 1 Y 1 B PHE 15  ? B PHE 15  
59 1 Y 1 B VAL 16  ? B VAL 16  
60 1 Y 1 B CYS 17  ? B CYS 17  
61 1 Y 1 B TRP 18  ? B TRP 18  
62 1 Y 1 B PHE 19  ? B PHE 19  
63 1 Y 1 B CYS 20  ? B CYS 20  
64 1 Y 1 B CYS 21  ? B CYS 21  
65 1 Y 1 B LEU 22  ? B LEU 22  
66 1 Y 1 B ALA 23  ? B ALA 23  
67 1 Y 1 B THR 24  ? B THR 24  
68 1 Y 1 B ALA 25  ? B ALA 25  
69 1 Y 1 B ALA 26  ? B ALA 26  
70 1 Y 1 B PRO 27  ? B PRO 27  
71 1 Y 1 B LEU 28  ? B LEU 28  
72 1 Y 1 B THR 29  ? B THR 29  
73 1 Y 1 B SER 30  ? B SER 30  
74 1 Y 1 B ILE 522 ? B ILE 522 
75 1 Y 1 B ASN 523 ? B ASN 523 
76 1 Y 1 B ASP 524 ? B ASP 524 
77 1 Y 1 B ARG 525 ? B ARG 525 
78 1 Y 1 B SER 526 ? B SER 526 
79 1 Y 1 B HIS 527 ? B HIS 527 
80 1 Y 1 B HIS 528 ? B HIS 528 
81 1 Y 1 B HIS 529 ? B HIS 529 
82 1 Y 1 B HIS 530 ? B HIS 530 
83 1 Y 1 B HIS 531 ? B HIS 531 
84 1 Y 1 B HIS 532 ? B HIS 532 
85 1 Y 1 B HIS 533 ? B HIS 533 
86 1 Y 1 B HIS 534 ? B HIS 534 
87 1 Y 1 B HIS 535 ? B HIS 535 
88 1 Y 1 B HIS 536 ? B HIS 536 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
NAG C1   C  N R 250 
NAG C2   C  N R 251 
NAG C3   C  N R 252 
NAG C4   C  N S 253 
NAG C5   C  N R 254 
NAG C6   C  N N 255 
NAG C7   C  N N 256 
NAG C8   C  N N 257 
NAG N2   N  N N 258 
NAG O1   O  N N 259 
NAG O3   O  N N 260 
NAG O4   O  N N 261 
NAG O5   O  N N 262 
NAG O6   O  N N 263 
NAG O7   O  N N 264 
NAG H1   H  N N 265 
NAG H2   H  N N 266 
NAG H3   H  N N 267 
NAG H4   H  N N 268 
NAG H5   H  N N 269 
NAG H61  H  N N 270 
NAG H62  H  N N 271 
NAG H81  H  N N 272 
NAG H82  H  N N 273 
NAG H83  H  N N 274 
NAG HN2  H  N N 275 
NAG HO1  H  N N 276 
NAG HO3  H  N N 277 
NAG HO4  H  N N 278 
NAG HO6  H  N N 279 
PHE N    N  N N 280 
PHE CA   C  N S 281 
PHE C    C  N N 282 
PHE O    O  N N 283 
PHE CB   C  N N 284 
PHE CG   C  Y N 285 
PHE CD1  C  Y N 286 
PHE CD2  C  Y N 287 
PHE CE1  C  Y N 288 
PHE CE2  C  Y N 289 
PHE CZ   C  Y N 290 
PHE OXT  O  N N 291 
PHE H    H  N N 292 
PHE H2   H  N N 293 
PHE HA   H  N N 294 
PHE HB2  H  N N 295 
PHE HB3  H  N N 296 
PHE HD1  H  N N 297 
PHE HD2  H  N N 298 
PHE HE1  H  N N 299 
PHE HE2  H  N N 300 
PHE HZ   H  N N 301 
PHE HXT  H  N N 302 
PRO N    N  N N 303 
PRO CA   C  N S 304 
PRO C    C  N N 305 
PRO O    O  N N 306 
PRO CB   C  N N 307 
PRO CG   C  N N 308 
PRO CD   C  N N 309 
PRO OXT  O  N N 310 
PRO H    H  N N 311 
PRO HA   H  N N 312 
PRO HB2  H  N N 313 
PRO HB3  H  N N 314 
PRO HG2  H  N N 315 
PRO HG3  H  N N 316 
PRO HD2  H  N N 317 
PRO HD3  H  N N 318 
PRO HXT  H  N N 319 
SER N    N  N N 320 
SER CA   C  N S 321 
SER C    C  N N 322 
SER O    O  N N 323 
SER CB   C  N N 324 
SER OG   O  N N 325 
SER OXT  O  N N 326 
SER H    H  N N 327 
SER H2   H  N N 328 
SER HA   H  N N 329 
SER HB2  H  N N 330 
SER HB3  H  N N 331 
SER HG   H  N N 332 
SER HXT  H  N N 333 
THR N    N  N N 334 
THR CA   C  N S 335 
THR C    C  N N 336 
THR O    O  N N 337 
THR CB   C  N R 338 
THR OG1  O  N N 339 
THR CG2  C  N N 340 
THR OXT  O  N N 341 
THR H    H  N N 342 
THR H2   H  N N 343 
THR HA   H  N N 344 
THR HB   H  N N 345 
THR HG1  H  N N 346 
THR HG21 H  N N 347 
THR HG22 H  N N 348 
THR HG23 H  N N 349 
THR HXT  H  N N 350 
TRP N    N  N N 351 
TRP CA   C  N S 352 
TRP C    C  N N 353 
TRP O    O  N N 354 
TRP CB   C  N N 355 
TRP CG   C  Y N 356 
TRP CD1  C  Y N 357 
TRP CD2  C  Y N 358 
TRP NE1  N  Y N 359 
TRP CE2  C  Y N 360 
TRP CE3  C  Y N 361 
TRP CZ2  C  Y N 362 
TRP CZ3  C  Y N 363 
TRP CH2  C  Y N 364 
TRP OXT  O  N N 365 
TRP H    H  N N 366 
TRP H2   H  N N 367 
TRP HA   H  N N 368 
TRP HB2  H  N N 369 
TRP HB3  H  N N 370 
TRP HD1  H  N N 371 
TRP HE1  H  N N 372 
TRP HE3  H  N N 373 
TRP HZ2  H  N N 374 
TRP HZ3  H  N N 375 
TRP HH2  H  N N 376 
TRP HXT  H  N N 377 
TYR N    N  N N 378 
TYR CA   C  N S 379 
TYR C    C  N N 380 
TYR O    O  N N 381 
TYR CB   C  N N 382 
TYR CG   C  Y N 383 
TYR CD1  C  Y N 384 
TYR CD2  C  Y N 385 
TYR CE1  C  Y N 386 
TYR CE2  C  Y N 387 
TYR CZ   C  Y N 388 
TYR OH   O  N N 389 
TYR OXT  O  N N 390 
TYR H    H  N N 391 
TYR H2   H  N N 392 
TYR HA   H  N N 393 
TYR HB2  H  N N 394 
TYR HB3  H  N N 395 
TYR HD1  H  N N 396 
TYR HD2  H  N N 397 
TYR HE1  H  N N 398 
TYR HE2  H  N N 399 
TYR HH   H  N N 400 
TYR HXT  H  N N 401 
VAL N    N  N N 402 
VAL CA   C  N S 403 
VAL C    C  N N 404 
VAL O    O  N N 405 
VAL CB   C  N N 406 
VAL CG1  C  N N 407 
VAL CG2  C  N N 408 
VAL OXT  O  N N 409 
VAL H    H  N N 410 
VAL H2   H  N N 411 
VAL HA   H  N N 412 
VAL HB   H  N N 413 
VAL HG11 H  N N 414 
VAL HG12 H  N N 415 
VAL HG13 H  N N 416 
VAL HG21 H  N N 417 
VAL HG22 H  N N 418 
VAL HG23 H  N N 419 
VAL HXT  H  N N 420 
ZN  ZN   ZN N N 421 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
NAG C1  C2   sing N N 237 
NAG C1  O1   sing N N 238 
NAG C1  O5   sing N N 239 
NAG C1  H1   sing N N 240 
NAG C2  C3   sing N N 241 
NAG C2  N2   sing N N 242 
NAG C2  H2   sing N N 243 
NAG C3  C4   sing N N 244 
NAG C3  O3   sing N N 245 
NAG C3  H3   sing N N 246 
NAG C4  C5   sing N N 247 
NAG C4  O4   sing N N 248 
NAG C4  H4   sing N N 249 
NAG C5  C6   sing N N 250 
NAG C5  O5   sing N N 251 
NAG C5  H5   sing N N 252 
NAG C6  O6   sing N N 253 
NAG C6  H61  sing N N 254 
NAG C6  H62  sing N N 255 
NAG C7  C8   sing N N 256 
NAG C7  N2   sing N N 257 
NAG C7  O7   doub N N 258 
NAG C8  H81  sing N N 259 
NAG C8  H82  sing N N 260 
NAG C8  H83  sing N N 261 
NAG N2  HN2  sing N N 262 
NAG O1  HO1  sing N N 263 
NAG O3  HO3  sing N N 264 
NAG O4  HO4  sing N N 265 
NAG O6  HO6  sing N N 266 
PHE N   CA   sing N N 267 
PHE N   H    sing N N 268 
PHE N   H2   sing N N 269 
PHE CA  C    sing N N 270 
PHE CA  CB   sing N N 271 
PHE CA  HA   sing N N 272 
PHE C   O    doub N N 273 
PHE C   OXT  sing N N 274 
PHE CB  CG   sing N N 275 
PHE CB  HB2  sing N N 276 
PHE CB  HB3  sing N N 277 
PHE CG  CD1  doub Y N 278 
PHE CG  CD2  sing Y N 279 
PHE CD1 CE1  sing Y N 280 
PHE CD1 HD1  sing N N 281 
PHE CD2 CE2  doub Y N 282 
PHE CD2 HD2  sing N N 283 
PHE CE1 CZ   doub Y N 284 
PHE CE1 HE1  sing N N 285 
PHE CE2 CZ   sing Y N 286 
PHE CE2 HE2  sing N N 287 
PHE CZ  HZ   sing N N 288 
PHE OXT HXT  sing N N 289 
PRO N   CA   sing N N 290 
PRO N   CD   sing N N 291 
PRO N   H    sing N N 292 
PRO CA  C    sing N N 293 
PRO CA  CB   sing N N 294 
PRO CA  HA   sing N N 295 
PRO C   O    doub N N 296 
PRO C   OXT  sing N N 297 
PRO CB  CG   sing N N 298 
PRO CB  HB2  sing N N 299 
PRO CB  HB3  sing N N 300 
PRO CG  CD   sing N N 301 
PRO CG  HG2  sing N N 302 
PRO CG  HG3  sing N N 303 
PRO CD  HD2  sing N N 304 
PRO CD  HD3  sing N N 305 
PRO OXT HXT  sing N N 306 
SER N   CA   sing N N 307 
SER N   H    sing N N 308 
SER N   H2   sing N N 309 
SER CA  C    sing N N 310 
SER CA  CB   sing N N 311 
SER CA  HA   sing N N 312 
SER C   O    doub N N 313 
SER C   OXT  sing N N 314 
SER CB  OG   sing N N 315 
SER CB  HB2  sing N N 316 
SER CB  HB3  sing N N 317 
SER OG  HG   sing N N 318 
SER OXT HXT  sing N N 319 
THR N   CA   sing N N 320 
THR N   H    sing N N 321 
THR N   H2   sing N N 322 
THR CA  C    sing N N 323 
THR CA  CB   sing N N 324 
THR CA  HA   sing N N 325 
THR C   O    doub N N 326 
THR C   OXT  sing N N 327 
THR CB  OG1  sing N N 328 
THR CB  CG2  sing N N 329 
THR CB  HB   sing N N 330 
THR OG1 HG1  sing N N 331 
THR CG2 HG21 sing N N 332 
THR CG2 HG22 sing N N 333 
THR CG2 HG23 sing N N 334 
THR OXT HXT  sing N N 335 
TRP N   CA   sing N N 336 
TRP N   H    sing N N 337 
TRP N   H2   sing N N 338 
TRP CA  C    sing N N 339 
TRP CA  CB   sing N N 340 
TRP CA  HA   sing N N 341 
TRP C   O    doub N N 342 
TRP C   OXT  sing N N 343 
TRP CB  CG   sing N N 344 
TRP CB  HB2  sing N N 345 
TRP CB  HB3  sing N N 346 
TRP CG  CD1  doub Y N 347 
TRP CG  CD2  sing Y N 348 
TRP CD1 NE1  sing Y N 349 
TRP CD1 HD1  sing N N 350 
TRP CD2 CE2  doub Y N 351 
TRP CD2 CE3  sing Y N 352 
TRP NE1 CE2  sing Y N 353 
TRP NE1 HE1  sing N N 354 
TRP CE2 CZ2  sing Y N 355 
TRP CE3 CZ3  doub Y N 356 
TRP CE3 HE3  sing N N 357 
TRP CZ2 CH2  doub Y N 358 
TRP CZ2 HZ2  sing N N 359 
TRP CZ3 CH2  sing Y N 360 
TRP CZ3 HZ3  sing N N 361 
TRP CH2 HH2  sing N N 362 
TRP OXT HXT  sing N N 363 
TYR N   CA   sing N N 364 
TYR N   H    sing N N 365 
TYR N   H2   sing N N 366 
TYR CA  C    sing N N 367 
TYR CA  CB   sing N N 368 
TYR CA  HA   sing N N 369 
TYR C   O    doub N N 370 
TYR C   OXT  sing N N 371 
TYR CB  CG   sing N N 372 
TYR CB  HB2  sing N N 373 
TYR CB  HB3  sing N N 374 
TYR CG  CD1  doub Y N 375 
TYR CG  CD2  sing Y N 376 
TYR CD1 CE1  sing Y N 377 
TYR CD1 HD1  sing N N 378 
TYR CD2 CE2  doub Y N 379 
TYR CD2 HD2  sing N N 380 
TYR CE1 CZ   doub Y N 381 
TYR CE1 HE1  sing N N 382 
TYR CE2 CZ   sing Y N 383 
TYR CE2 HE2  sing N N 384 
TYR CZ  OH   sing N N 385 
TYR OH  HH   sing N N 386 
TYR OXT HXT  sing N N 387 
VAL N   CA   sing N N 388 
VAL N   H    sing N N 389 
VAL N   H2   sing N N 390 
VAL CA  C    sing N N 391 
VAL CA  CB   sing N N 392 
VAL CA  HA   sing N N 393 
VAL C   O    doub N N 394 
VAL C   OXT  sing N N 395 
VAL CB  CG1  sing N N 396 
VAL CB  CG2  sing N N 397 
VAL CB  HB   sing N N 398 
VAL CG1 HG11 sing N N 399 
VAL CG1 HG12 sing N N 400 
VAL CG1 HG13 sing N N 401 
VAL CG2 HG21 sing N N 402 
VAL CG2 HG22 sing N N 403 
VAL CG2 HG23 sing N N 404 
VAL OXT HXT  sing N N 405 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM134744 1 
'Cancer Prevention and Research Institute of Texas (CPRIT)'                                'United States' RR160029    2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NTI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014400 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009152 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005771 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 6.96715  ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 29.81721 ?       ? ? 5.87945  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . THR A 1 29  ? 66.57192  -32.50808 -46.51715 1.000 103.75485 ? 29  THR A N   1 
ATOM   2    C  CA  . THR A 1 29  ? 65.49765  -32.37270 -47.49408 1.000 102.66849 ? 29  THR A CA  1 
ATOM   3    C  C   . THR A 1 29  ? 65.06408  -30.91476 -47.61799 1.000 109.87588 ? 29  THR A C   1 
ATOM   4    O  O   . THR A 1 29  ? 64.84156  -30.23944 -46.61382 1.000 109.40419 ? 29  THR A O   1 
ATOM   5    C  CB  . THR A 1 29  ? 64.27521  -33.23740 -47.11859 1.000 101.84878 ? 29  THR A CB  1 
ATOM   6    O  OG1 . THR A 1 29  ? 64.68502  -34.59632 -46.92122 1.000 117.56148 ? 29  THR A OG1 1 
ATOM   7    C  CG2 . THR A 1 29  ? 63.22371  -33.18562 -48.21725 1.000 89.11000  ? 29  THR A CG2 1 
ATOM   8    N  N   . SER A 1 30  ? 64.95264  -30.43340 -48.85868 1.000 110.62242 ? 30  SER A N   1 
ATOM   9    C  CA  . SER A 1 30  ? 64.52540  -29.05574 -49.08244 1.000 91.35927  ? 30  SER A CA  1 
ATOM   10   C  C   . SER A 1 30  ? 63.09843  -28.83416 -48.59619 1.000 94.69288  ? 30  SER A C   1 
ATOM   11   O  O   . SER A 1 30  ? 62.78818  -27.78686 -48.01543 1.000 98.68542  ? 30  SER A O   1 
ATOM   12   C  CB  . SER A 1 30  ? 64.65052  -28.70361 -50.56388 1.000 84.64785  ? 30  SER A CB  1 
ATOM   13   O  OG  . SER A 1 30  ? 65.98287  -28.86898 -51.01531 1.000 87.29503  ? 30  SER A OG  1 
ATOM   14   N  N   . LYS A 1 31  ? 62.21273  -29.80515 -48.83254 1.000 85.90302  ? 31  LYS A N   1 
ATOM   15   C  CA  . LYS A 1 31  ? 60.85052  -29.69495 -48.32259 1.000 80.68863  ? 31  LYS A CA  1 
ATOM   16   C  C   . LYS A 1 31  ? 60.82799  -29.72023 -46.79835 1.000 96.14685  ? 31  LYS A C   1 
ATOM   17   O  O   . LYS A 1 31  ? 60.09812  -28.94429 -46.17213 1.000 98.94078  ? 31  LYS A O   1 
ATOM   18   C  CB  . LYS A 1 31  ? 59.97905  -30.81297 -48.89541 1.000 78.97668  ? 31  LYS A CB  1 
ATOM   19   C  CG  . LYS A 1 31  ? 58.48327  -30.57854 -48.72635 1.000 72.39203  ? 31  LYS A CG  1 
ATOM   20   C  CD  . LYS A 1 31  ? 57.66223  -31.63277 -49.45377 1.000 80.13802  ? 31  LYS A CD  1 
ATOM   21   C  CE  . LYS A 1 31  ? 56.17161  -31.35911 -49.32110 1.000 85.32344  ? 31  LYS A CE  1 
ATOM   22   N  NZ  . LYS A 1 31  ? 55.35177  -32.33267 -50.09566 1.000 82.43265  ? 31  LYS A NZ  1 
ATOM   23   N  N   . ALA A 1 32  ? 61.62339  -30.59949 -46.18251 1.000 96.52412  ? 32  ALA A N   1 
ATOM   24   C  CA  . ALA A 1 32  ? 61.64374  -30.67804 -44.72434 1.000 90.63655  ? 32  ALA A CA  1 
ATOM   25   C  C   . ALA A 1 32  ? 62.18469  -29.39600 -44.10191 1.000 76.74037  ? 32  ALA A C   1 
ATOM   26   O  O   . ALA A 1 32  ? 61.63836  -28.90316 -43.10797 1.000 79.38899  ? 32  ALA A O   1 
ATOM   27   C  CB  . ALA A 1 32  ? 62.46910  -31.88239 -44.27211 1.000 97.07723  ? 32  ALA A CB  1 
ATOM   28   N  N   . ALA A 1 33  ? 63.26023  -28.84308 -44.66697 1.000 73.53616  ? 33  ALA A N   1 
ATOM   29   C  CA  . ALA A 1 33  ? 63.80846  -27.59479 -44.14414 1.000 79.89286  ? 33  ALA A CA  1 
ATOM   30   C  C   . ALA A 1 33  ? 62.81539  -26.45134 -44.29725 1.000 89.08415  ? 33  ALA A C   1 
ATOM   31   O  O   . ALA A 1 33  ? 62.66653  -25.62003 -43.39374 1.000 95.89832  ? 33  ALA A O   1 
ATOM   32   C  CB  . ALA A 1 33  ? 65.12206  -27.26131 -44.84999 1.000 71.39454  ? 33  ALA A CB  1 
ATOM   33   N  N   . TYR A 1 34  ? 62.13131  -26.39170 -45.44009 1.000 89.13726  ? 34  TYR A N   1 
ATOM   34   C  CA  . TYR A 1 34  ? 61.13416  -25.35061 -45.66543 1.000 84.63116  ? 34  TYR A CA  1 
ATOM   35   C  C   . TYR A 1 34  ? 60.00771  -25.43585 -44.64336 1.000 84.92107  ? 34  TYR A C   1 
ATOM   36   O  O   . TYR A 1 34  ? 59.58187  -24.41865 -44.08555 1.000 92.78441  ? 34  TYR A O   1 
ATOM   37   C  CB  . TYR A 1 34  ? 60.58776  -25.46941 -47.08885 1.000 69.91424  ? 34  TYR A CB  1 
ATOM   38   C  CG  . TYR A 1 34  ? 59.47171  -24.50866 -47.42831 1.000 78.87570  ? 34  TYR A CG  1 
ATOM   39   C  CD1 . TYR A 1 34  ? 59.74507  -23.26099 -47.97269 1.000 69.56628  ? 34  TYR A CD1 1 
ATOM   40   C  CD2 . TYR A 1 34  ? 58.14238  -24.85925 -47.22605 1.000 76.30870  ? 34  TYR A CD2 1 
ATOM   41   C  CE1 . TYR A 1 34  ? 58.72834  -22.38634 -48.29328 1.000 65.65767  ? 34  TYR A CE1 1 
ATOM   42   C  CE2 . TYR A 1 34  ? 57.12186  -23.99166 -47.54205 1.000 82.00026  ? 34  TYR A CE2 1 
ATOM   43   C  CZ  . TYR A 1 34  ? 57.42038  -22.75881 -48.07494 1.000 77.78484  ? 34  TYR A CZ  1 
ATOM   44   O  OH  . TYR A 1 34  ? 56.40270  -21.89694 -48.39197 1.000 76.08104  ? 34  TYR A OH  1 
ATOM   45   N  N   . LEU A 1 35  ? 59.50740  -26.64794 -44.39056 1.000 71.34368  ? 35  LEU A N   1 
ATOM   46   C  CA  . LEU A 1 35  ? 58.39169  -26.80938 -43.46491 1.000 71.93754  ? 35  LEU A CA  1 
ATOM   47   C  C   . LEU A 1 35  ? 58.78615  -26.45818 -42.03552 1.000 81.21525  ? 35  LEU A C   1 
ATOM   48   O  O   . LEU A 1 35  ? 57.94615  -25.98590 -41.26005 1.000 82.44114  ? 35  LEU A O   1 
ATOM   49   C  CB  . LEU A 1 35  ? 57.84979  -28.23597 -43.54447 1.000 74.70398  ? 35  LEU A CB  1 
ATOM   50   C  CG  . LEU A 1 35  ? 57.26541  -28.63582 -44.90311 1.000 72.40677  ? 35  LEU A CG  1 
ATOM   51   C  CD1 . LEU A 1 35  ? 56.97186  -30.12560 -44.95272 1.000 86.13061  ? 35  LEU A CD1 1 
ATOM   52   C  CD2 . LEU A 1 35  ? 56.01461  -27.83079 -45.21553 1.000 83.04656  ? 35  LEU A CD2 1 
ATOM   53   N  N   . LEU A 1 36  ? 60.04815  -26.68588 -41.66286 1.000 84.82001  ? 36  LEU A N   1 
ATOM   54   C  CA  . LEU A 1 36  ? 60.50947  -26.27056 -40.34098 1.000 88.65975  ? 36  LEU A CA  1 
ATOM   55   C  C   . LEU A 1 36  ? 60.55959  -24.75243 -40.23238 1.000 85.95628  ? 36  LEU A C   1 
ATOM   56   O  O   . LEU A 1 36  ? 60.08164  -24.17189 -39.25061 1.000 95.49917  ? 36  LEU A O   1 
ATOM   57   C  CB  . LEU A 1 36  ? 61.88534  -26.86858 -40.04489 1.000 89.03317  ? 36  LEU A CB  1 
ATOM   58   C  CG  . LEU A 1 36  ? 61.96683  -28.37701 -39.82143 1.000 94.27303  ? 36  LEU A CG  1 
ATOM   59   C  CD1 . LEU A 1 36  ? 63.37249  -28.77116 -39.39383 1.000 97.69676  ? 36  LEU A CD1 1 
ATOM   60   C  CD2 . LEU A 1 36  ? 60.94316  -28.81717 -38.78913 1.000 67.87863  ? 36  LEU A CD2 1 
ATOM   61   N  N   . LYS A 1 37  ? 61.14259  -24.09301 -41.23641 1.000 84.79240  ? 37  LYS A N   1 
ATOM   62   C  CA  . LYS A 1 37  ? 61.19853  -22.63565 -41.23913 1.000 84.79869  ? 37  LYS A CA  1 
ATOM   63   C  C   . LYS A 1 37  ? 59.80606  -22.02462 -41.31277 1.000 82.19339  ? 37  LYS A C   1 
ATOM   64   O  O   . LYS A 1 37  ? 59.56789  -20.95210 -40.74497 1.000 86.48709  ? 37  LYS A O   1 
ATOM   65   C  CB  . LYS A 1 37  ? 62.06918  -22.15661 -42.40354 1.000 77.38148  ? 37  LYS A CB  1 
ATOM   66   C  CG  . LYS A 1 37  ? 62.11360  -20.64847 -42.60546 1.000 87.76617  ? 37  LYS A CG  1 
ATOM   67   C  CD  . LYS A 1 37  ? 62.62264  -19.91179 -41.37796 1.000 101.31117 ? 37  LYS A CD  1 
ATOM   68   C  CE  . LYS A 1 37  ? 62.65079  -18.40995 -41.62241 1.000 88.76658  ? 37  LYS A CE  1 
ATOM   69   N  NZ  . LYS A 1 37  ? 62.95715  -17.64485 -40.38366 1.000 91.56351  ? 37  LYS A NZ  1 
ATOM   70   N  N   . ARG A 1 38  ? 58.87647  -22.68925 -42.00164 1.000 70.26123  ? 38  ARG A N   1 
ATOM   71   C  CA  . ARG A 1 38  ? 57.50927  -22.18612 -42.08604 1.000 63.16048  ? 38  ARG A CA  1 
ATOM   72   C  C   . ARG A 1 38  ? 56.80057  -22.28353 -40.74299 1.000 73.55632  ? 38  ARG A C   1 
ATOM   73   O  O   . ARG A 1 38  ? 56.13624  -21.33596 -40.31082 1.000 83.91180  ? 38  ARG A O   1 
ATOM   74   C  CB  . ARG A 1 38  ? 56.73187  -22.95265 -43.15445 1.000 62.35304  ? 38  ARG A CB  1 
ATOM   75   C  CG  . ARG A 1 38  ? 55.28107  -22.52673 -43.26799 1.000 61.59897  ? 38  ARG A CG  1 
ATOM   76   C  CD  . ARG A 1 38  ? 54.52451  -23.38397 -44.26654 1.000 70.68591  ? 38  ARG A CD  1 
ATOM   77   N  NE  . ARG A 1 38  ? 53.16295  -22.90220 -44.46153 1.000 66.39086  ? 38  ARG A NE  1 
ATOM   78   C  CZ  . ARG A 1 38  ? 52.15320  -23.16150 -43.64220 1.000 73.28354  ? 38  ARG A CZ  1 
ATOM   79   N  NH1 . ARG A 1 38  ? 52.31345  -23.91076 -42.56354 1.000 58.95291  ? 38  ARG A NH1 1 
ATOM   80   N  NH2 . ARG A 1 38  ? 50.95485  -22.64906 -43.90688 1.000 66.00068  ? 38  ARG A NH2 1 
ATOM   81   N  N   . ASN A 1 39  ? 56.91966  -23.43131 -40.07503 1.000 82.83857  ? 39  ASN A N   1 
ATOM   82   C  CA  . ASN A 1 39  ? 56.24674  -23.61187 -38.79385 1.000 88.63223  ? 39  ASN A CA  1 
ATOM   83   C  C   . ASN A 1 39  ? 56.81903  -22.67256 -37.74101 1.000 85.12235  ? 39  ASN A C   1 
ATOM   84   O  O   . ASN A 1 39  ? 56.08220  -22.15961 -36.89205 1.000 85.27137  ? 39  ASN A O   1 
ATOM   85   C  CB  . ASN A 1 39  ? 56.34404  -25.06900 -38.34572 1.000 75.18874  ? 39  ASN A CB  1 
ATOM   86   C  CG  . ASN A 1 39  ? 55.48290  -25.99128 -39.18806 1.000 84.86776  ? 39  ASN A CG  1 
ATOM   87   O  OD1 . ASN A 1 39  ? 54.81371  -25.55629 -40.12508 1.000 91.33195  ? 39  ASN A OD1 1 
ATOM   88   N  ND2 . ASN A 1 39  ? 55.50125  -27.27835 -38.85861 1.000 72.57948  ? 39  ASN A ND2 1 
ATOM   89   N  N   . SER A 1 40  ? 58.13061  -22.42773 -37.78329 1.000 76.82976  ? 40  SER A N   1 
ATOM   90   C  CA  . SER A 1 40  ? 58.71755  -21.43044 -36.89698 1.000 78.25558  ? 40  SER A CA  1 
ATOM   91   C  C   . SER A 1 40  ? 58.15811  -20.04462 -37.18733 1.000 81.42743  ? 40  SER A C   1 
ATOM   92   O  O   . SER A 1 40  ? 57.87625  -19.27358 -36.26306 1.000 79.27147  ? 40  SER A O   1 
ATOM   93   C  CB  . SER A 1 40  ? 60.23737  -21.43485 -37.03806 1.000 85.63712  ? 40  SER A CB  1 
ATOM   94   O  OG  . SER A 1 40  ? 60.79665  -20.26549 -36.46081 1.000 90.75519  ? 40  SER A OG  1 
ATOM   95   N  N   . LEU A 1 41  ? 57.99216  -19.71140 -38.46875 1.000 82.29447  ? 41  LEU A N   1 
ATOM   96   C  CA  . LEU A 1 41  ? 57.50879  -18.38639 -38.84151 1.000 77.42445  ? 41  LEU A CA  1 
ATOM   97   C  C   . LEU A 1 41  ? 56.07167  -18.16782 -38.37971 1.000 82.51114  ? 41  LEU A C   1 
ATOM   98   O  O   . LEU A 1 41  ? 55.75384  -17.13434 -37.77952 1.000 89.13267  ? 41  LEU A O   1 
ATOM   99   C  CB  . LEU A 1 41  ? 57.62609  -18.20525 -40.35458 1.000 69.83431  ? 41  LEU A CB  1 
ATOM   100  C  CG  . LEU A 1 41  ? 57.63970  -16.77435 -40.89084 1.000 78.64106  ? 41  LEU A CG  1 
ATOM   101  C  CD1 . LEU A 1 41  ? 58.77277  -15.98604 -40.25825 1.000 90.31394  ? 41  LEU A CD1 1 
ATOM   102  C  CD2 . LEU A 1 41  ? 57.77428  -16.78127 -42.40383 1.000 70.50219  ? 41  LEU A CD2 1 
ATOM   103  N  N   . ILE A 1 42  ? 55.18735  -19.13050 -38.65334 1.000 71.04483  ? 42  ILE A N   1 
ATOM   104  C  CA  . ILE A 1 42  ? 53.78304  -18.98689 -38.27165 1.000 70.88060  ? 42  ILE A CA  1 
ATOM   105  C  C   . ILE A 1 42  ? 53.63903  -18.97051 -36.75425 1.000 81.77342  ? 42  ILE A C   1 
ATOM   106  O  O   . ILE A 1 42  ? 52.92808  -18.13095 -36.18941 1.000 81.70570  ? 42  ILE A O   1 
ATOM   107  C  CB  . ILE A 1 42  ? 52.93506  -20.10253 -38.90951 1.000 70.85967  ? 42  ILE A CB  1 
ATOM   108  C  CG1 . ILE A 1 42  ? 52.81863  -19.88463 -40.42063 1.000 79.22724  ? 42  ILE A CG1 1 
ATOM   109  C  CG2 . ILE A 1 42  ? 51.55791  -20.17181 -38.26333 1.000 69.69345  ? 42  ILE A CG2 1 
ATOM   110  C  CD1 . ILE A 1 42  ? 51.85008  -20.82767 -41.10704 1.000 83.89279  ? 42  ILE A CD1 1 
ATOM   111  N  N   . GLU A 1 43  ? 54.31220  -19.89995 -36.07044 1.000 85.65762  ? 43  GLU A N   1 
ATOM   112  C  CA  . GLU A 1 43  ? 54.23050  -19.95539 -34.61493 1.000 90.45620  ? 43  GLU A CA  1 
ATOM   113  C  C   . GLU A 1 43  ? 54.87895  -18.74829 -33.95127 1.000 86.19924  ? 43  GLU A C   1 
ATOM   114  O  O   . GLU A 1 43  ? 54.52151  -18.41711 -32.81652 1.000 93.50644  ? 43  GLU A O   1 
ATOM   115  C  CB  . GLU A 1 43  ? 54.86966  -21.24405 -34.09790 1.000 97.55950  ? 43  GLU A CB  1 
ATOM   116  C  CG  . GLU A 1 43  ? 54.11458  -22.50379 -34.48493 1.000 101.63524 ? 43  GLU A CG  1 
ATOM   117  C  CD  . GLU A 1 43  ? 54.96494  -23.75035 -34.34775 1.000 111.06242 ? 43  GLU A CD  1 
ATOM   118  O  OE1 . GLU A 1 43  ? 56.10852  -23.63863 -33.85717 1.000 110.54767 ? 43  GLU A OE1 1 
ATOM   119  O  OE2 . GLU A 1 43  ? 54.49491  -24.84045 -34.73538 1.000 126.21245 ? 43  GLU A OE2 1 
ATOM   120  N  N   . GLU A 1 44  ? 55.82341  -18.08858 -34.62555 1.000 82.12378  ? 44  GLU A N   1 
ATOM   121  C  CA  . GLU A 1 44  ? 56.37789  -16.84709 -34.09870 1.000 85.36722  ? 44  GLU A CA  1 
ATOM   122  C  C   . GLU A 1 44  ? 55.41273  -15.68390 -34.28045 1.000 88.35153  ? 44  GLU A C   1 
ATOM   123  O  O   . GLU A 1 44  ? 55.39267  -14.76247 -33.45682 1.000 86.69024  ? 44  GLU A O   1 
ATOM   124  C  CB  . GLU A 1 44  ? 57.71525  -16.53467 -34.77178 1.000 85.34342  ? 44  GLU A CB  1 
ATOM   125  C  CG  . GLU A 1 44  ? 58.42212  -15.30462 -34.22556 1.000 100.35633 ? 44  GLU A CG  1 
ATOM   126  C  CD  . GLU A 1 44  ? 59.73005  -15.01827 -34.93819 1.000 119.04648 ? 44  GLU A CD  1 
ATOM   127  O  OE1 . GLU A 1 44  ? 60.32257  -15.96302 -35.50219 1.000 115.53955 ? 44  GLU A OE1 1 
ATOM   128  O  OE2 . GLU A 1 44  ? 60.16212  -13.84608 -34.93971 1.000 118.73792 ? 44  GLU A OE2 1 
ATOM   129  N  N   . ASP A 1 45  ? 54.61184  -15.70639 -35.34656 1.000 87.22901  ? 45  ASP A N   1 
ATOM   130  C  CA  . ASP A 1 45  ? 53.59731  -14.67515 -35.52868 1.000 77.70887  ? 45  ASP A CA  1 
ATOM   131  C  C   . ASP A 1 45  ? 52.44949  -14.85911 -34.54300 1.000 80.97985  ? 45  ASP A C   1 
ATOM   132  O  O   . ASP A 1 45  ? 51.99384  -13.89493 -33.91667 1.000 84.10044  ? 45  ASP A O   1 
ATOM   133  C  CB  . ASP A 1 45  ? 53.08153  -14.69698 -36.96683 1.000 79.95792  ? 45  ASP A CB  1 
ATOM   134  C  CG  . ASP A 1 45  ? 52.17948  -13.52119 -37.27736 1.000 77.66604  ? 45  ASP A CG  1 
ATOM   135  O  OD1 . ASP A 1 45  ? 52.70508  -12.45176 -37.65207 1.000 72.73667  ? 45  ASP A OD1 1 
ATOM   136  O  OD2 . ASP A 1 45  ? 50.94665  -13.66294 -37.13536 1.000 72.31885  ? 45  ASP A OD2 1 
ATOM   137  N  N   . ALA A 1 46  ? 51.96914  -16.09615 -34.39214 1.000 74.23975  ? 46  ALA A N   1 
ATOM   138  C  CA  . ALA A 1 46  ? 50.84931  -16.36389 -33.49791 1.000 76.42210  ? 46  ALA A CA  1 
ATOM   139  C  C   . ALA A 1 46  ? 51.23748  -16.26959 -32.02912 1.000 83.78955  ? 46  ALA A C   1 
ATOM   140  O  O   . ALA A 1 46  ? 50.35187  -16.17262 -31.17323 1.000 85.88416  ? 46  ALA A O   1 
ATOM   141  C  CB  . ALA A 1 46  ? 50.26258  -17.74499 -33.79051 1.000 79.89551  ? 46  ALA A CB  1 
ATOM   142  N  N   . SER A 1 47  ? 52.53334  -16.30037 -31.71616 1.000 81.98417  ? 47  SER A N   1 
ATOM   143  C  CA  . SER A 1 47  ? 52.97399  -16.17069 -30.33304 1.000 76.03559  ? 47  SER A CA  1 
ATOM   144  C  C   . SER A 1 47  ? 52.86778  -14.74457 -29.80911 1.000 82.95327  ? 47  SER A C   1 
ATOM   145  O  O   . SER A 1 47  ? 53.08277  -14.52592 -28.61231 1.000 94.01367  ? 47  SER A O   1 
ATOM   146  C  CB  . SER A 1 47  ? 54.41732  -16.65743 -30.19087 1.000 78.43913  ? 47  SER A CB  1 
ATOM   147  O  OG  . SER A 1 47  ? 55.31288  -15.81704 -30.89662 1.000 78.66593  ? 47  SER A OG  1 
ATOM   148  N  N   . ARG A 1 48  ? 52.55727  -13.77639 -30.66733 1.000 80.18584  ? 48  ARG A N   1 
ATOM   149  C  CA  . ARG A 1 48  ? 52.49656  -12.37336 -30.28658 1.000 75.74709  ? 48  ARG A CA  1 
ATOM   150  C  C   . ARG A 1 48  ? 51.07122  -11.85554 -30.15005 1.000 79.37915  ? 48  ARG A C   1 
ATOM   151  O  O   . ARG A 1 48  ? 50.87695  -10.64905 -29.97971 1.000 85.40944  ? 48  ARG A O   1 
ATOM   152  C  CB  . ARG A 1 48  ? 53.25858  -11.53041 -31.30697 1.000 60.06486  ? 48  ARG A CB  1 
ATOM   153  C  CG  . ARG A 1 48  ? 54.68495  -11.98923 -31.52492 1.000 62.66644  ? 48  ARG A CG  1 
ATOM   154  C  CD  . ARG A 1 48  ? 55.34262  -11.19529 -32.62785 1.000 73.69398  ? 48  ARG A CD  1 
ATOM   155  N  NE  . ARG A 1 48  ? 55.07798  -9.76970  -32.48235 1.000 63.17424  ? 48  ARG A NE  1 
ATOM   156  C  CZ  . ARG A 1 48  ? 55.88060  -8.81400  -32.92577 1.000 64.56056  ? 48  ARG A CZ  1 
ATOM   157  N  NH1 . ARG A 1 48  ? 57.03895  -9.09714  -33.49674 1.000 62.21656  ? 48  ARG A NH1 1 
ATOM   158  N  NH2 . ARG A 1 48  ? 55.51423  -7.54334  -32.78689 1.000 71.63518  ? 48  ARG A NH2 1 
ATOM   159  N  N   . LYS A 1 49  ? 50.07455  -12.73188 -30.22110 1.000 69.59984  ? 49  LYS A N   1 
ATOM   160  C  CA  . LYS A 1 49  ? 48.68467  -12.31367 -30.17121 1.000 65.76972  ? 49  LYS A CA  1 
ATOM   161  C  C   . LYS A 1 49  ? 48.22475  -12.17456 -28.72023 1.000 77.57257  ? 49  LYS A C   1 
ATOM   162  O  O   . LYS A 1 49  ? 48.96999  -12.44177 -27.77380 1.000 76.19471  ? 49  LYS A O   1 
ATOM   163  C  CB  . LYS A 1 49  ? 47.82313  -13.29767 -30.95848 1.000 69.94754  ? 49  LYS A CB  1 
ATOM   164  C  CG  . LYS A 1 49  ? 48.50151  -13.74736 -32.24404 1.000 100.15514 ? 49  LYS A CG  1 
ATOM   165  C  CD  . LYS A 1 49  ? 47.56212  -13.76976 -33.43542 1.000 102.72257 ? 49  LYS A CD  1 
ATOM   166  C  CE  . LYS A 1 49  ? 48.34973  -13.90639 -34.73253 1.000 87.95608  ? 49  LYS A CE  1 
ATOM   167  N  NZ  . LYS A 1 49  ? 47.46729  -14.06524 -35.91943 1.000 87.44713  ? 49  LYS A NZ  1 
ATOM   168  N  N   . LEU A 1 50  ? 46.97952  -11.73794 -28.54198 1.000 76.74096  ? 50  LEU A N   1 
ATOM   169  C  CA  . LEU A 1 50  ? 46.42675  -11.53725 -27.20892 1.000 64.38115  ? 50  LEU A CA  1 
ATOM   170  C  C   . LEU A 1 50  ? 46.01690  -12.87563 -26.60822 1.000 77.41951  ? 50  LEU A C   1 
ATOM   171  O  O   . LEU A 1 50  ? 45.27429  -13.64456 -27.22772 1.000 86.42996  ? 50  LEU A O   1 
ATOM   172  C  CB  . LEU A 1 50  ? 45.22700  -10.59245 -27.26404 1.000 66.06262  ? 50  LEU A CB  1 
ATOM   173  C  CG  . LEU A 1 50  ? 44.69150  -10.12251 -25.90996 1.000 68.92156  ? 50  LEU A CG  1 
ATOM   174  C  CD1 . LEU A 1 50  ? 45.40621  -8.86137  -25.44062 1.000 69.41089  ? 50  LEU A CD1 1 
ATOM   175  C  CD2 . LEU A 1 50  ? 43.18913  -9.90987  -25.97010 1.000 64.62814  ? 50  LEU A CD2 1 
ATOM   176  N  N   . GLY A 1 51  ? 46.49319  -13.14601 -25.39709 1.000 83.74232  ? 51  GLY A N   1 
ATOM   177  C  CA  . GLY A 1 51  ? 46.27257  -14.42766 -24.76464 1.000 73.41645  ? 51  GLY A CA  1 
ATOM   178  C  C   . GLY A 1 51  ? 47.27425  -15.49802 -25.13001 1.000 73.28448  ? 51  GLY A C   1 
ATOM   179  O  O   . GLY A 1 51  ? 47.08888  -16.65584 -24.73594 1.000 73.54333  ? 51  GLY A O   1 
ATOM   180  N  N   . ALA A 1 52  ? 48.32966  -15.15113 -25.87155 1.000 68.18829  ? 52  ALA A N   1 
ATOM   181  C  CA  . ALA A 1 52  ? 49.34784  -16.11714 -26.26421 1.000 64.31038  ? 52  ALA A CA  1 
ATOM   182  C  C   . ALA A 1 52  ? 50.14042  -16.65981 -25.08328 1.000 72.51445  ? 52  ALA A C   1 
ATOM   183  O  O   . ALA A 1 52  ? 50.85074  -17.65820 -25.24550 1.000 75.17661  ? 52  ALA A O   1 
ATOM   184  C  CB  . ALA A 1 52  ? 50.30531  -15.48646 -27.27591 1.000 59.41337  ? 52  ALA A CB  1 
ATOM   185  N  N   . LYS A 1 53  ? 50.04645  -16.03280 -23.91203 1.000 78.47018  ? 53  LYS A N   1 
ATOM   186  C  CA  . LYS A 1 53  ? 50.74496  -16.49887 -22.72393 1.000 76.91267  ? 53  LYS A CA  1 
ATOM   187  C  C   . LYS A 1 53  ? 49.81371  -17.12167 -21.69370 1.000 70.10455  ? 53  LYS A C   1 
ATOM   188  O  O   . LYS A 1 53  ? 50.28297  -17.55202 -20.63449 1.000 76.41498  ? 53  LYS A O   1 
ATOM   189  C  CB  . LYS A 1 53  ? 51.53950  -15.34729 -22.09767 1.000 77.26461  ? 53  LYS A CB  1 
ATOM   190  C  CG  . LYS A 1 53  ? 52.50776  -14.70738 -23.08094 1.000 69.44952  ? 53  LYS A CG  1 
ATOM   191  C  CD  . LYS A 1 53  ? 53.51476  -13.80002 -22.40460 1.000 86.26580  ? 53  LYS A CD  1 
ATOM   192  C  CE  . LYS A 1 53  ? 54.54541  -13.30836 -23.40949 1.000 96.09147  ? 53  LYS A CE  1 
ATOM   193  N  NZ  . LYS A 1 53  ? 55.58964  -12.46240 -22.77125 1.000 118.20081 ? 53  LYS A NZ  1 
ATOM   194  N  N   . ILE A 1 54  ? 48.51252  -17.18006 -21.97094 1.000 65.15040  ? 54  ILE A N   1 
ATOM   195  C  CA  . ILE A 1 54  ? 47.59719  -17.94255 -21.13025 1.000 68.23755  ? 54  ILE A CA  1 
ATOM   196  C  C   . ILE A 1 54  ? 47.87754  -19.42528 -21.33402 1.000 67.72399  ? 54  ILE A C   1 
ATOM   197  O  O   . ILE A 1 54  ? 47.81338  -19.93473 -22.45928 1.000 79.79777  ? 54  ILE A O   1 
ATOM   198  C  CB  . ILE A 1 54  ? 46.13656  -17.60521 -21.45845 1.000 62.96294  ? 54  ILE A CB  1 
ATOM   199  C  CG1 . ILE A 1 54  ? 45.75615  -16.23336 -20.89542 1.000 68.09318  ? 54  ILE A CG1 1 
ATOM   200  C  CG2 . ILE A 1 54  ? 45.20341  -18.68231 -20.92133 1.000 56.34286  ? 54  ILE A CG2 1 
ATOM   201  C  CD1 . ILE A 1 54  ? 45.50351  -16.23370 -19.40347 1.000 75.07733  ? 54  ILE A CD1 1 
ATOM   202  N  N   . VAL A 1 55  ? 48.19819  -20.12301 -20.24928 1.000 67.79281  ? 55  VAL A N   1 
ATOM   203  C  CA  . VAL A 1 55  ? 48.38634  -21.56820 -20.27433 1.000 72.60605  ? 55  VAL A CA  1 
ATOM   204  C  C   . VAL A 1 55  ? 47.16038  -22.20311 -19.63556 1.000 67.59389  ? 55  VAL A C   1 
ATOM   205  O  O   . VAL A 1 55  ? 46.86242  -21.95542 -18.46053 1.000 72.52796  ? 55  VAL A O   1 
ATOM   206  C  CB  . VAL A 1 55  ? 49.67620  -21.98545 -19.55143 1.000 73.20735  ? 55  VAL A CB  1 
ATOM   207  C  CG1 . VAL A 1 55  ? 49.80340  -23.50161 -19.53328 1.000 71.27914  ? 55  VAL A CG1 1 
ATOM   208  C  CG2 . VAL A 1 55  ? 50.88646  -21.35566 -20.22673 1.000 68.70638  ? 55  VAL A CG2 1 
ATOM   209  N  N   . LEU A 1 56  ? 46.44524  -23.01346 -20.40885 1.000 62.60392  ? 56  LEU A N   1 
ATOM   210  C  CA  . LEU A 1 56  ? 45.18164  -23.58458 -19.97025 1.000 60.46813  ? 56  LEU A CA  1 
ATOM   211  C  C   . LEU A 1 56  ? 45.38939  -24.95068 -19.33334 1.000 68.86680  ? 56  LEU A C   1 
ATOM   212  O  O   . LEU A 1 56  ? 46.21298  -25.74768 -19.79248 1.000 70.39345  ? 56  LEU A O   1 
ATOM   213  C  CB  . LEU A 1 56  ? 44.21296  -23.71033 -21.14677 1.000 62.48817  ? 56  LEU A CB  1 
ATOM   214  C  CG  . LEU A 1 56  ? 43.75838  -22.40859 -21.80426 1.000 64.48966  ? 56  LEU A CG  1 
ATOM   215  C  CD1 . LEU A 1 56  ? 42.93977  -22.70609 -23.04765 1.000 68.27837  ? 56  LEU A CD1 1 
ATOM   216  C  CD2 . LEU A 1 56  ? 42.95812  -21.56770 -20.82470 1.000 74.89011  ? 56  LEU A CD2 1 
ATOM   217  N  N   . THR A 1 57  ? 44.63561  -25.21275 -18.26914 1.000 77.68407  ? 57  THR A N   1 
ATOM   218  C  CA  . THR A 1 57  ? 44.56751  -26.55719 -17.72344 1.000 73.46465  ? 57  THR A CA  1 
ATOM   219  C  C   . THR A 1 57  ? 43.84353  -27.47070 -18.70756 1.000 72.89762  ? 57  THR A C   1 
ATOM   220  O  O   . THR A 1 57  ? 43.13897  -27.01459 -19.61243 1.000 65.79002  ? 57  THR A O   1 
ATOM   221  C  CB  . THR A 1 57  ? 43.84385  -26.56214 -16.37558 1.000 74.95096  ? 57  THR A CB  1 
ATOM   222  O  OG1 . THR A 1 57  ? 42.42747  -26.56337 -16.59173 1.000 83.80194  ? 57  THR A OG1 1 
ATOM   223  C  CG2 . THR A 1 57  ? 44.21952  -25.33045 -15.56642 1.000 79.72028  ? 57  THR A CG2 1 
ATOM   224  N  N   . ASN A 1 58  ? 44.03602  -28.78027 -18.53235 1.000 72.34618  ? 58  ASN A N   1 
ATOM   225  C  CA  . ASN A 1 58  ? 43.37992  -29.73711 -19.41779 1.000 75.15531  ? 58  ASN A CA  1 
ATOM   226  C  C   . ASN A 1 58  ? 41.86414  -29.60303 -19.36019 1.000 74.30962  ? 58  ASN A C   1 
ATOM   227  O  O   . ASN A 1 58  ? 41.18154  -29.84120 -20.36352 1.000 80.43102  ? 58  ASN A O   1 
ATOM   228  C  CB  . ASN A 1 58  ? 43.80629  -31.16196 -19.06517 1.000 82.31000  ? 58  ASN A CB  1 
ATOM   229  C  CG  . ASN A 1 58  ? 45.25715  -31.43659 -19.40564 1.000 77.51034  ? 58  ASN A CG  1 
ATOM   230  O  OD1 . ASN A 1 58  ? 45.99384  -30.53781 -19.81181 1.000 81.17697  ? 58  ASN A OD1 1 
ATOM   231  N  ND2 . ASN A 1 58  ? 45.67654  -32.68461 -19.23816 1.000 83.90516  ? 58  ASN A ND2 1 
ATOM   232  N  N   . GLU A 1 59  ? 41.32146  -29.22137 -18.20146 1.000 75.02808  ? 59  GLU A N   1 
ATOM   233  C  CA  . GLU A 1 59  ? 39.88722  -28.96972 -18.10317 1.000 77.57324  ? 59  GLU A CA  1 
ATOM   234  C  C   . GLU A 1 59  ? 39.47622  -27.77688 -18.95817 1.000 71.06715  ? 59  GLU A C   1 
ATOM   235  O  O   . GLU A 1 59  ? 38.44250  -27.81779 -19.63552 1.000 70.43766  ? 59  GLU A O   1 
ATOM   236  C  CB  . GLU A 1 59  ? 39.48827  -28.74236 -16.64400 1.000 82.88230  ? 59  GLU A CB  1 
ATOM   237  C  CG  . GLU A 1 59  ? 39.67669  -29.95439 -15.73923 1.000 109.19589 ? 59  GLU A CG  1 
ATOM   238  C  CD  . GLU A 1 59  ? 41.08442  -30.06491 -15.17989 1.000 117.55408 ? 59  GLU A CD  1 
ATOM   239  O  OE1 . GLU A 1 59  ? 41.89305  -29.13967 -15.40683 1.000 103.97273 ? 59  GLU A OE1 1 
ATOM   240  O  OE2 . GLU A 1 59  ? 41.37968  -31.07710 -14.50841 1.000 113.22706 ? 59  GLU A OE2 1 
ATOM   241  N  N   . GLU A 1 60  ? 40.26937  -26.70267 -18.93305 1.000 62.19212  ? 60  GLU A N   1 
ATOM   242  C  CA  . GLU A 1 60  ? 39.95969  -25.53319 -19.74795 1.000 65.82601  ? 60  GLU A CA  1 
ATOM   243  C  C   . GLU A 1 60  ? 40.11288  -25.83082 -21.23283 1.000 73.31408  ? 60  GLU A C   1 
ATOM   244  O  O   . GLU A 1 60  ? 39.40368  -25.24114 -22.05838 1.000 77.50946  ? 60  GLU A O   1 
ATOM   245  C  CB  . GLU A 1 60  ? 40.84788  -24.35920 -19.33826 1.000 66.27727  ? 60  GLU A CB  1 
ATOM   246  C  CG  . GLU A 1 60  ? 40.69022  -23.95905 -17.88148 1.000 63.98878  ? 60  GLU A CG  1 
ATOM   247  C  CD  . GLU A 1 60  ? 41.48026  -22.71775 -17.52397 1.000 73.47569  ? 60  GLU A CD  1 
ATOM   248  O  OE1 . GLU A 1 60  ? 42.69687  -22.67743 -17.80373 1.000 67.74845  ? 60  GLU A OE1 1 
ATOM   249  O  OE2 . GLU A 1 60  ? 40.87856  -21.77933 -16.96352 1.000 76.21854  ? 60  GLU A OE2 1 
ATOM   250  N  N   . LYS A 1 61  ? 41.02833  -26.73598 -21.58926 1.000 69.12894  ? 61  LYS A N   1 
ATOM   251  C  CA  . LYS A 1 61  ? 41.16946  -27.15326 -22.97754 1.000 60.45052  ? 61  LYS A CA  1 
ATOM   252  C  C   . LYS A 1 61  ? 39.94533  -27.90597 -23.48377 1.000 63.12360  ? 61  LYS A C   1 
ATOM   253  O  O   . LYS A 1 61  ? 39.70668  -27.92857 -24.69552 1.000 78.65311  ? 61  LYS A O   1 
ATOM   254  C  CB  . LYS A 1 61  ? 42.41686  -28.02451 -23.13615 1.000 54.15884  ? 61  LYS A CB  1 
ATOM   255  C  CG  . LYS A 1 61  ? 43.72124  -27.29564 -22.84448 1.000 69.40917  ? 61  LYS A CG  1 
ATOM   256  C  CD  . LYS A 1 61  ? 44.91537  -28.22983 -22.94349 1.000 61.88036  ? 61  LYS A CD  1 
ATOM   257  C  CE  . LYS A 1 61  ? 46.21043  -27.48967 -22.64930 1.000 61.18746  ? 61  LYS A CE  1 
ATOM   258  N  NZ  . LYS A 1 61  ? 47.39464  -28.39188 -22.66297 1.000 64.42397  ? 61  LYS A NZ  1 
ATOM   259  N  N   . VAL A 1 62  ? 39.16942  -28.52331 -22.58938 1.000 56.06765  ? 62  VAL A N   1 
ATOM   260  C  CA  . VAL A 1 62  ? 37.93441  -29.18830 -23.00236 1.000 56.15056  ? 62  VAL A CA  1 
ATOM   261  C  C   . VAL A 1 62  ? 36.92379  -28.16374 -23.50464 1.000 65.79235  ? 62  VAL A C   1 
ATOM   262  O  O   . VAL A 1 62  ? 36.29986  -28.34608 -24.55676 1.000 78.69626  ? 62  VAL A O   1 
ATOM   263  C  CB  . VAL A 1 62  ? 37.36073  -30.02854 -21.84565 1.000 59.24352  ? 62  VAL A CB  1 
ATOM   264  C  CG1 . VAL A 1 62  ? 35.97576  -30.56020 -22.19744 1.000 63.14477  ? 62  VAL A CG1 1 
ATOM   265  C  CG2 . VAL A 1 62  ? 38.30356  -31.17434 -21.49278 1.000 65.80713  ? 62  VAL A CG2 1 
ATOM   266  N  N   . LEU A 1 63  ? 36.74309  -27.07177 -22.75577 1.000 64.47653  ? 63  LEU A N   1 
ATOM   267  C  CA  . LEU A 1 63  ? 35.87510  -25.99197 -23.21795 1.000 64.62826  ? 63  LEU A CA  1 
ATOM   268  C  C   . LEU A 1 63  ? 36.42548  -25.34261 -24.48040 1.000 69.46323  ? 63  LEU A C   1 
ATOM   269  O  O   . LEU A 1 63  ? 35.66665  -25.00581 -25.39717 1.000 67.09890  ? 63  LEU A O   1 
ATOM   270  C  CB  . LEU A 1 63  ? 35.69918  -24.94531 -22.11785 1.000 51.71060  ? 63  LEU A CB  1 
ATOM   271  C  CG  . LEU A 1 63  ? 34.63449  -25.21325 -21.05589 1.000 58.15148  ? 63  LEU A CG  1 
ATOM   272  C  CD1 . LEU A 1 63  ? 34.64397  -24.11429 -20.00898 1.000 67.84856  ? 63  LEU A CD1 1 
ATOM   273  C  CD2 . LEU A 1 63  ? 33.26548  -25.31783 -21.70519 1.000 59.01729  ? 63  LEU A CD2 1 
ATOM   274  N  N   . ASP A 1 64  ? 37.74623  -25.15537 -24.54087 1.000 73.35659  ? 64  ASP A N   1 
ATOM   275  C  CA  . ASP A 1 64  ? 38.35750  -24.51329 -25.69957 1.000 74.99014  ? 64  ASP A CA  1 
ATOM   276  C  C   . ASP A 1 64  ? 38.08566  -25.29732 -26.97714 1.000 77.31180  ? 64  ASP A C   1 
ATOM   277  O  O   . ASP A 1 64  ? 37.82228  -24.70757 -28.03129 1.000 82.77090  ? 64  ASP A O   1 
ATOM   278  C  CB  . ASP A 1 64  ? 39.86073  -24.35325 -25.47199 1.000 76.90979  ? 64  ASP A CB  1 
ATOM   279  C  CG  . ASP A 1 64  ? 40.57323  -23.78290 -26.67874 1.000 77.57341  ? 64  ASP A CG  1 
ATOM   280  O  OD1 . ASP A 1 64  ? 40.23575  -22.65280 -27.09147 1.000 82.04456  ? 64  ASP A OD1 1 
ATOM   281  O  OD2 . ASP A 1 64  ? 41.47229  -24.46566 -27.21278 1.000 67.20904  ? 64  ASP A OD2 1 
ATOM   282  N  N   . ASP A 1 65  ? 38.14509  -26.62686 -26.90494 1.000 71.59394  ? 65  ASP A N   1 
ATOM   283  C  CA  . ASP A 1 65  ? 37.89521  -27.44980 -28.08057 1.000 74.31391  ? 65  ASP A CA  1 
ATOM   284  C  C   . ASP A 1 65  ? 36.41507  -27.54187 -28.43152 1.000 68.01381  ? 65  ASP A C   1 
ATOM   285  O  O   . ASP A 1 65  ? 36.08533  -27.83274 -29.58708 1.000 71.32642  ? 65  ASP A O   1 
ATOM   286  C  CB  . ASP A 1 65  ? 38.47569  -28.85256 -27.87816 1.000 89.85492  ? 65  ASP A CB  1 
ATOM   287  C  CG  . ASP A 1 65  ? 39.99084  -28.84559 -27.73747 1.000 92.19725  ? 65  ASP A CG  1 
ATOM   288  O  OD1 . ASP A 1 65  ? 40.58372  -27.74757 -27.67699 1.000 89.63338  ? 65  ASP A OD1 1 
ATOM   289  O  OD2 . ASP A 1 65  ? 40.59119  -29.94011 -27.69180 1.000 106.48414 ? 65  ASP A OD2 1 
ATOM   290  N  N   . PHE A 1 66  ? 35.51925  -27.31441 -27.46748 1.000 69.36320  ? 66  PHE A N   1 
ATOM   291  C  CA  . PHE A 1 66  ? 34.09793  -27.24243 -27.79267 1.000 75.50151  ? 66  PHE A CA  1 
ATOM   292  C  C   . PHE A 1 66  ? 33.77576  -25.96062 -28.55180 1.000 74.03259  ? 66  PHE A C   1 
ATOM   293  O  O   . PHE A 1 66  ? 32.95979  -25.97011 -29.48103 1.000 70.01318  ? 66  PHE A O   1 
ATOM   294  C  CB  . PHE A 1 66  ? 33.25822  -27.33997 -26.51805 1.000 63.56383  ? 66  PHE A CB  1 
ATOM   295  C  CG  . PHE A 1 66  ? 31.77287  -27.29226 -26.76208 1.000 62.65158  ? 66  PHE A CG  1 
ATOM   296  C  CD1 . PHE A 1 66  ? 31.13959  -28.30532 -27.46212 1.000 74.76594  ? 66  PHE A CD1 1 
ATOM   297  C  CD2 . PHE A 1 66  ? 31.00947  -26.23648 -26.28762 1.000 79.67462  ? 66  PHE A CD2 1 
ATOM   298  C  CE1 . PHE A 1 66  ? 29.77470  -28.26723 -27.68717 1.000 80.81051  ? 66  PHE A CE1 1 
ATOM   299  C  CE2 . PHE A 1 66  ? 29.64347  -26.19252 -26.51094 1.000 84.32113  ? 66  PHE A CE2 1 
ATOM   300  C  CZ  . PHE A 1 66  ? 29.02615  -27.20904 -27.21133 1.000 72.66835  ? 66  PHE A CZ  1 
ATOM   301  N  N   . ILE A 1 67  ? 34.40611  -24.84877 -28.16866 1.000 72.02312  ? 67  ILE A N   1 
ATOM   302  C  CA  . ILE A 1 67  ? 34.17796  -23.58234 -28.85894 1.000 71.80310  ? 67  ILE A CA  1 
ATOM   303  C  C   . ILE A 1 67  ? 34.86740  -23.57841 -30.21884 1.000 72.84966  ? 67  ILE A C   1 
ATOM   304  O  O   . ILE A 1 67  ? 34.26214  -23.22123 -31.23573 1.000 70.40754  ? 67  ILE A O   1 
ATOM   305  C  CB  . ILE A 1 67  ? 34.64632  -22.40236 -27.98852 1.000 57.66745  ? 67  ILE A CB  1 
ATOM   306  C  CG1 . ILE A 1 67  ? 33.72210  -22.22236 -26.78255 1.000 65.46227  ? 67  ILE A CG1 1 
ATOM   307  C  CG2 . ILE A 1 67  ? 34.70952  -21.12522 -28.81116 1.000 61.04089  ? 67  ILE A CG2 1 
ATOM   308  C  CD1 . ILE A 1 67  ? 34.07952  -21.03753 -25.90262 1.000 66.30373  ? 67  ILE A CD1 1 
ATOM   309  N  N   . LEU A 1 68  ? 36.14791  -23.96516 -30.25649 1.000 66.78919  ? 68  LEU A N   1 
ATOM   310  C  CA  . LEU A 1 68  ? 36.88022  -23.99581 -31.52023 1.000 64.41045  ? 68  LEU A CA  1 
ATOM   311  C  C   . LEU A 1 68  ? 36.18401  -24.86952 -32.55358 1.000 66.85952  ? 68  LEU A C   1 
ATOM   312  O  O   . LEU A 1 68  ? 36.29448  -24.61209 -33.75683 1.000 69.32582  ? 68  LEU A O   1 
ATOM   313  C  CB  . LEU A 1 68  ? 38.31048  -24.49124 -31.29597 1.000 63.21392  ? 68  LEU A CB  1 
ATOM   314  C  CG  . LEU A 1 68  ? 39.37509  -23.48154 -30.86151 1.000 58.88397  ? 68  LEU A CG  1 
ATOM   315  C  CD1 . LEU A 1 68  ? 40.65526  -24.19686 -30.46038 1.000 49.42240  ? 68  LEU A CD1 1 
ATOM   316  C  CD2 . LEU A 1 68  ? 39.64874  -22.48603 -31.97653 1.000 57.22665  ? 68  LEU A CD2 1 
ATOM   317  N  N   . ALA A 1 69  ? 35.46916  -25.90493 -32.10938 1.000 59.63904  ? 69  ALA A N   1 
ATOM   318  C  CA  . ALA A 1 69  ? 34.76735  -26.77622 -33.04666 1.000 64.17291  ? 69  ALA A CA  1 
ATOM   319  C  C   . ALA A 1 69  ? 33.67752  -26.01877 -33.79616 1.000 71.38212  ? 69  ALA A C   1 
ATOM   320  O  O   . ALA A 1 69  ? 33.61784  -26.05529 -35.03056 1.000 77.66837  ? 69  ALA A O   1 
ATOM   321  C  CB  . ALA A 1 69  ? 34.17867  -27.97702 -32.30716 1.000 69.99992  ? 69  ALA A CB  1 
ATOM   322  N  N   . GLU A 1 70  ? 32.80130  -25.32418 -33.06593 1.000 70.35095  ? 70  GLU A N   1 
ATOM   323  C  CA  . GLU A 1 70  ? 31.71867  -24.60064 -33.72596 1.000 70.34409  ? 70  GLU A CA  1 
ATOM   324  C  C   . GLU A 1 70  ? 32.24524  -23.38259 -34.47418 1.000 69.04468  ? 70  GLU A C   1 
ATOM   325  O  O   . GLU A 1 70  ? 31.71984  -23.02380 -35.53474 1.000 75.91922  ? 70  GLU A O   1 
ATOM   326  C  CB  . GLU A 1 70  ? 30.65233  -24.19407 -32.70899 1.000 61.82590  ? 70  GLU A CB  1 
ATOM   327  C  CG  . GLU A 1 70  ? 29.30744  -23.86886 -33.34561 1.000 72.73698  ? 70  GLU A CG  1 
ATOM   328  C  CD  . GLU A 1 70  ? 28.23107  -23.54685 -32.32760 1.000 87.04415  ? 70  GLU A CD  1 
ATOM   329  O  OE1 . GLU A 1 70  ? 28.56598  -23.00006 -31.25597 1.000 82.22903  ? 70  GLU A OE1 1 
ATOM   330  O  OE2 . GLU A 1 70  ? 27.04853  -23.84546 -32.60063 1.000 89.31348  ? 70  GLU A OE2 1 
ATOM   331  N  N   . LYS A 1 71  ? 33.27429  -22.72962 -33.93112 1.000 65.21696  ? 71  LYS A N   1 
ATOM   332  C  CA  . LYS A 1 71  ? 33.91023  -21.61649 -34.62963 1.000 64.75710  ? 71  LYS A CA  1 
ATOM   333  C  C   . LYS A 1 71  ? 34.46058  -22.05775 -35.98154 1.000 69.28997  ? 71  LYS A C   1 
ATOM   334  O  O   . LYS A 1 71  ? 34.21235  -21.41398 -37.00705 1.000 55.61108  ? 71  LYS A O   1 
ATOM   335  C  CB  . LYS A 1 71  ? 35.01953  -21.03179 -33.75542 1.000 61.93706  ? 71  LYS A CB  1 
ATOM   336  C  CG  . LYS A 1 71  ? 35.95082  -20.06941 -34.46279 1.000 62.79332  ? 71  LYS A CG  1 
ATOM   337  C  CD  . LYS A 1 71  ? 35.46584  -18.63872 -34.35550 1.000 59.86193  ? 71  LYS A CD  1 
ATOM   338  C  CE  . LYS A 1 71  ? 36.62657  -17.67811 -34.51016 1.000 63.58358  ? 71  LYS A CE  1 
ATOM   339  N  NZ  . LYS A 1 71  ? 37.58744  -17.83373 -33.38452 1.000 49.31726  ? 71  LYS A NZ  1 
ATOM   340  N  N   . ARG A 1 72  ? 35.20158  -23.16868 -36.00291 1.000 74.74761  ? 72  ARG A N   1 
ATOM   341  C  CA  . ARG A 1 72  ? 35.77579  -23.65840 -37.25263 1.000 70.62099  ? 72  ARG A CA  1 
ATOM   342  C  C   . ARG A 1 72  ? 34.71039  -24.23317 -38.17762 1.000 64.45507  ? 72  ARG A C   1 
ATOM   343  O  O   . ARG A 1 72  ? 34.87905  -24.21389 -39.40195 1.000 65.31310  ? 72  ARG A O   1 
ATOM   344  C  CB  . ARG A 1 72  ? 36.85398  -24.70110 -36.96122 1.000 61.39104  ? 72  ARG A CB  1 
ATOM   345  C  CG  . ARG A 1 72  ? 38.10221  -24.11746 -36.31672 1.000 62.38512  ? 72  ARG A CG  1 
ATOM   346  C  CD  . ARG A 1 72  ? 38.95009  -25.18453 -35.64381 1.000 59.15818  ? 72  ARG A CD  1 
ATOM   347  N  NE  . ARG A 1 72  ? 40.21423  -24.64173 -35.16025 1.000 65.72814  ? 72  ARG A NE  1 
ATOM   348  C  CZ  . ARG A 1 72  ? 41.07922  -25.30824 -34.40799 1.000 68.28037  ? 72  ARG A CZ  1 
ATOM   349  N  NH1 . ARG A 1 72  ? 40.83969  -26.54735 -34.01147 1.000 67.65544  ? 72  ARG A NH1 1 
ATOM   350  N  NH2 . ARG A 1 72  ? 42.21299  -24.71576 -34.04321 1.000 66.98893  ? 72  ARG A NH2 1 
ATOM   351  N  N   . LYS A 1 73  ? 33.61941  -24.75930 -37.61701 1.000 58.88952  ? 73  LYS A N   1 
ATOM   352  C  CA  . LYS A 1 73  ? 32.52745  -25.25732 -38.44707 1.000 60.34406  ? 73  LYS A CA  1 
ATOM   353  C  C   . LYS A 1 73  ? 31.88071  -24.12996 -39.24177 1.000 67.37280  ? 73  LYS A C   1 
ATOM   354  O  O   . LYS A 1 73  ? 31.61900  -24.27567 -40.44252 1.000 70.15746  ? 73  LYS A O   1 
ATOM   355  C  CB  . LYS A 1 73  ? 31.49490  -25.96759 -37.57135 1.000 67.79413  ? 73  LYS A CB  1 
ATOM   356  C  CG  . LYS A 1 73  ? 30.11116  -26.08879 -38.18499 1.000 73.78762  ? 73  LYS A CG  1 
ATOM   357  C  CD  . LYS A 1 73  ? 29.11336  -26.56779 -37.14171 1.000 84.39909  ? 73  LYS A CD  1 
ATOM   358  C  CE  . LYS A 1 73  ? 27.67740  -26.42235 -37.61626 1.000 77.29079  ? 73  LYS A CE  1 
ATOM   359  N  NZ  . LYS A 1 73  ? 26.71846  -26.67944 -36.50423 1.000 73.07035  ? 73  LYS A NZ  1 
ATOM   360  N  N   . LEU A 1 74  ? 31.62669  -22.99136 -38.59090 1.000 65.06238  ? 74  LEU A N   1 
ATOM   361  C  CA  . LEU A 1 74  ? 31.01765  -21.85812 -39.27844 1.000 58.12396  ? 74  LEU A CA  1 
ATOM   362  C  C   . LEU A 1 74  ? 32.01384  -21.13782 -40.18121 1.000 57.16736  ? 74  LEU A C   1 
ATOM   363  O  O   . LEU A 1 74  ? 31.63986  -20.65303 -41.25322 1.000 42.26980  ? 74  LEU A O   1 
ATOM   364  C  CB  . LEU A 1 74  ? 30.42234  -20.89055 -38.25562 1.000 47.96899  ? 74  LEU A CB  1 
ATOM   365  C  CG  . LEU A 1 74  ? 29.31784  -21.48407 -37.38124 1.000 54.22184  ? 74  LEU A CG  1 
ATOM   366  C  CD1 . LEU A 1 74  ? 28.73335  -20.42506 -36.46128 1.000 52.48566  ? 74  LEU A CD1 1 
ATOM   367  C  CD2 . LEU A 1 74  ? 28.23196  -22.12053 -38.23978 1.000 58.91727  ? 74  LEU A CD2 1 
ATOM   368  N  N   . ILE A 1 75  ? 33.27944  -21.05147 -39.76493 1.000 55.02967  ? 75  ILE A N   1 
ATOM   369  C  CA  . ILE A 1 75  ? 34.29328  -20.39547 -40.58945 1.000 45.78665  ? 75  ILE A CA  1 
ATOM   370  C  C   . ILE A 1 75  ? 34.50566  -21.16265 -41.88990 1.000 60.81620  ? 75  ILE A C   1 
ATOM   371  O  O   . ILE A 1 75  ? 34.53358  -20.57878 -42.97952 1.000 58.14488  ? 75  ILE A O   1 
ATOM   372  C  CB  . ILE A 1 75  ? 35.61061  -20.24446 -39.80472 1.000 42.59471  ? 75  ILE A CB  1 
ATOM   373  C  CG1 . ILE A 1 75  ? 35.49745  -19.12997 -38.76038 1.000 54.16363  ? 75  ILE A CG1 1 
ATOM   374  C  CG2 . ILE A 1 75  ? 36.77614  -19.97516 -40.74666 1.000 37.46317  ? 75  ILE A CG2 1 
ATOM   375  C  CD1 . ILE A 1 75  ? 36.76008  -18.92778 -37.94466 1.000 45.54294  ? 75  ILE A CD1 1 
ATOM   376  N  N   . ASP A 1 76  ? 34.64547  -22.48557 -41.79643 1.000 67.73489  ? 76  ASP A N   1 
ATOM   377  C  CA  . ASP A 1 76  ? 35.07410  -23.28949 -42.93603 1.000 62.01810  ? 76  ASP A CA  1 
ATOM   378  C  C   . ASP A 1 76  ? 33.91946  -23.71631 -43.83429 1.000 63.67256  ? 76  ASP A C   1 
ATOM   379  O  O   . ASP A 1 76  ? 34.07538  -23.75234 -45.06074 1.000 56.67629  ? 76  ASP A O   1 
ATOM   380  C  CB  . ASP A 1 76  ? 35.83956  -24.52167 -42.44765 1.000 62.02596  ? 76  ASP A CB  1 
ATOM   381  C  CG  . ASP A 1 76  ? 37.14957  -24.16117 -41.77375 1.000 74.41439  ? 76  ASP A CG  1 
ATOM   382  O  OD1 . ASP A 1 76  ? 37.87059  -23.29533 -42.30877 1.000 69.40165  ? 76  ASP A OD1 1 
ATOM   383  O  OD2 . ASP A 1 76  ? 37.45068  -24.74044 -40.70890 1.000 62.88523  ? 76  ASP A OD2 1 
ATOM   384  N  N   . ASP A 1 77  ? 32.76091  -24.03417 -43.26086 1.000 52.70617  ? 77  ASP A N   1 
ATOM   385  C  CA  . ASP A 1 77  ? 31.60222  -24.36145 -44.08055 1.000 72.20884  ? 77  ASP A CA  1 
ATOM   386  C  C   . ASP A 1 77  ? 30.85427  -23.12349 -44.55902 1.000 71.35540  ? 77  ASP A C   1 
ATOM   387  O  O   . ASP A 1 77  ? 29.79767  -23.25810 -45.18537 1.000 70.06877  ? 77  ASP A O   1 
ATOM   388  C  CB  . ASP A 1 77  ? 30.66422  -25.30648 -43.32635 1.000 76.90591  ? 77  ASP A CB  1 
ATOM   389  C  CG  . ASP A 1 77  ? 31.00813  -26.77032 -43.56082 1.000 87.87558  ? 77  ASP A CG  1 
ATOM   390  O  OD1 . ASP A 1 77  ? 31.58033  -27.08470 -44.62847 1.000 55.45686  ? 77  ASP A OD1 1 
ATOM   391  O  OD2 . ASP A 1 77  ? 30.71746  -27.60588 -42.67895 1.000 82.42809  ? 77  ASP A OD2 1 
ATOM   392  N  N   . SER A 1 78  ? 31.35955  -21.92991 -44.25444 1.000 69.73781  ? 78  SER A N   1 
ATOM   393  C  CA  . SER A 1 78  ? 30.96492  -20.71561 -44.95506 1.000 63.22879  ? 78  SER A CA  1 
ATOM   394  C  C   . SER A 1 78  ? 32.00863  -20.26310 -45.96221 1.000 63.41314  ? 78  SER A C   1 
ATOM   395  O  O   . SER A 1 78  ? 31.65392  -19.63621 -46.96537 1.000 71.95520  ? 78  SER A O   1 
ATOM   396  C  CB  . SER A 1 78  ? 30.70064  -19.57566 -43.96393 1.000 59.87061  ? 78  SER A CB  1 
ATOM   397  O  OG  . SER A 1 78  ? 30.43108  -18.35851 -44.63930 1.000 57.18756  ? 78  SER A OG  1 
ATOM   398  N  N   . ARG A 1 79  ? 33.28527  -20.57524 -45.71680 1.000 63.31622  ? 79  ARG A N   1 
ATOM   399  C  CA  . ARG A 1 79  ? 34.33599  -20.22077 -46.66514 1.000 58.61659  ? 79  ARG A CA  1 
ATOM   400  C  C   . ARG A 1 79  ? 34.27248  -21.08719 -47.91825 1.000 62.61083  ? 79  ARG A C   1 
ATOM   401  O  O   . ARG A 1 79  ? 34.43388  -20.58182 -49.03518 1.000 62.70840  ? 79  ARG A O   1 
ATOM   402  C  CB  . ARG A 1 79  ? 35.71073  -20.34239 -46.00394 1.000 49.20881  ? 79  ARG A CB  1 
ATOM   403  C  CG  . ARG A 1 79  ? 36.86605  -20.06870 -46.95843 1.000 56.80271  ? 79  ARG A CG  1 
ATOM   404  C  CD  . ARG A 1 79  ? 38.19225  -19.88159 -46.23409 1.000 59.58237  ? 79  ARG A CD  1 
ATOM   405  N  NE  . ARG A 1 79  ? 38.77230  -21.13843 -45.77721 1.000 65.32630  ? 79  ARG A NE  1 
ATOM   406  C  CZ  . ARG A 1 79  ? 39.58630  -21.89673 -46.49987 1.000 56.49111  ? 79  ARG A CZ  1 
ATOM   407  N  NH1 . ARG A 1 79  ? 39.91796  -21.57170 -47.73726 1.000 61.04838  ? 79  ARG A NH1 1 
ATOM   408  N  NH2 . ARG A 1 79  ? 40.08027  -23.01091 -45.96733 1.000 74.94901  ? 79  ARG A NH2 1 
ATOM   409  N  N   . LEU A 1 80  ? 34.03333  -22.38910 -47.75711 1.000 77.80612  ? 80  LEU A N   1 
ATOM   410  C  CA  . LEU A 1 80  ? 34.05679  -23.33306 -48.86848 1.000 69.31769  ? 80  LEU A CA  1 
ATOM   411  C  C   . LEU A 1 80  ? 32.67626  -23.61578 -49.44534 1.000 66.27678  ? 80  LEU A C   1 
ATOM   412  O  O   . LEU A 1 80  ? 32.52365  -23.65727 -50.66988 1.000 87.79420  ? 80  LEU A O   1 
ATOM   413  C  CB  . LEU A 1 80  ? 34.71079  -24.64309 -48.42892 1.000 68.01980  ? 80  LEU A CB  1 
ATOM   414  C  CG  . LEU A 1 80  ? 36.13477  -24.45867 -47.91327 1.000 51.85168  ? 80  LEU A CG  1 
ATOM   415  C  CD1 . LEU A 1 80  ? 36.67552  -25.74229 -47.30683 1.000 53.40708  ? 80  LEU A CD1 1 
ATOM   416  C  CD2 . LEU A 1 80  ? 37.05137  -23.95350 -49.02291 1.000 57.63524  ? 80  LEU A CD2 1 
ATOM   417  N  N   . ASN A 1 81  ? 31.66053  -23.80758 -48.60029 1.000 63.37109  ? 81  ASN A N   1 
ATOM   418  C  CA  . ASN A 1 81  ? 30.30258  -23.91053 -49.11834 1.000 72.23451  ? 81  ASN A CA  1 
ATOM   419  C  C   . ASN A 1 81  ? 29.77583  -22.57904 -49.63975 1.000 68.60087  ? 81  ASN A C   1 
ATOM   420  O  O   . ASN A 1 81  ? 28.64173  -22.53799 -50.13051 1.000 73.08815  ? 81  ASN A O   1 
ATOM   421  C  CB  . ASN A 1 81  ? 29.35286  -24.45564 -48.05213 1.000 74.04169  ? 81  ASN A CB  1 
ATOM   422  C  CG  . ASN A 1 81  ? 29.24086  -25.96579 -48.09141 1.000 74.39363  ? 81  ASN A CG  1 
ATOM   423  O  OD1 . ASN A 1 81  ? 28.64685  -26.52864 -49.01054 1.000 84.88830  ? 81  ASN A OD1 1 
ATOM   424  N  ND2 . ASN A 1 81  ? 29.80156  -26.63033 -47.08752 1.000 66.31798  ? 81  ASN A ND2 1 
ATOM   425  N  N   . GLN A 1 82  ? 30.55838  -21.50587 -49.52428 1.000 61.51807  ? 82  GLN A N   1 
ATOM   426  C  CA  . GLN A 1 82  ? 30.26436  -20.20374 -50.12228 1.000 68.43047  ? 82  GLN A CA  1 
ATOM   427  C  C   . GLN A 1 82  ? 28.87714  -19.69434 -49.72851 1.000 70.00627  ? 82  GLN A C   1 
ATOM   428  O  O   . GLN A 1 82  ? 27.98053  -19.52197 -50.55647 1.000 66.09698  ? 82  GLN A O   1 
ATOM   429  C  CB  . GLN A 1 82  ? 30.42165  -20.25614 -51.64292 1.000 81.67824  ? 82  GLN A CB  1 
ATOM   430  C  CG  . GLN A 1 82  ? 31.85507  -20.44470 -52.10795 1.000 83.63701  ? 82  GLN A CG  1 
ATOM   431  C  CD  . GLN A 1 82  ? 31.99229  -20.39202 -53.61950 1.000 91.27077  ? 82  GLN A CD  1 
ATOM   432  O  OE1 . GLN A 1 82  ? 31.23868  -19.69635 -54.30274 1.000 112.88307 ? 82  GLN A OE1 1 
ATOM   433  N  NE2 . GLN A 1 82  ? 32.95699  -21.13334 -54.14939 1.000 81.15878  ? 82  GLN A NE2 1 
ATOM   434  N  N   . THR A 1 83  ? 28.71880  -19.44615 -48.43086 1.000 74.79194  ? 83  THR A N   1 
ATOM   435  C  CA  . THR A 1 83  ? 27.50505  -18.87620 -47.86771 1.000 59.62736  ? 83  THR A CA  1 
ATOM   436  C  C   . THR A 1 83  ? 27.89027  -17.68759 -46.99615 1.000 61.80815  ? 83  THR A C   1 
ATOM   437  O  O   . THR A 1 83  ? 29.06750  -17.32962 -46.88768 1.000 63.51237  ? 83  THR A O   1 
ATOM   438  C  CB  . THR A 1 83  ? 26.72560  -19.92007 -47.05987 1.000 64.23475  ? 83  THR A CB  1 
ATOM   439  O  OG1 . THR A 1 83  ? 27.59676  -20.51376 -46.08936 1.000 76.27597  ? 83  THR A OG1 1 
ATOM   440  C  CG2 . THR A 1 83  ? 26.18043  -21.00518 -47.97549 1.000 67.65869  ? 83  THR A CG2 1 
ATOM   441  N  N   . GLU A 1 84  ? 26.89683  -17.06221 -46.36982 1.000 65.42507  ? 84  GLU A N   1 
ATOM   442  C  CA  . GLU A 1 84  ? 27.17763  -15.92397 -45.50717 1.000 63.26968  ? 84  GLU A CA  1 
ATOM   443  C  C   . GLU A 1 84  ? 27.60143  -16.38905 -44.12078 1.000 66.62563  ? 84  GLU A C   1 
ATOM   444  O  O   . GLU A 1 84  ? 27.04596  -17.34202 -43.56666 1.000 77.56912  ? 84  GLU A O   1 
ATOM   445  C  CB  . GLU A 1 84  ? 25.96756  -14.99894 -45.39122 1.000 57.82102  ? 84  GLU A CB  1 
ATOM   446  C  CG  . GLU A 1 84  ? 26.30974  -13.68126 -44.70149 1.000 73.06794  ? 84  GLU A CG  1 
ATOM   447  C  CD  . GLU A 1 84  ? 25.10029  -12.81687 -44.41875 1.000 86.01198  ? 84  GLU A CD  1 
ATOM   448  O  OE1 . GLU A 1 84  ? 23.96727  -13.33887 -44.46652 1.000 76.63130  ? 84  GLU A OE1 1 
ATOM   449  O  OE2 . GLU A 1 84  ? 25.28767  -11.61233 -44.14317 1.000 90.96901  ? 84  GLU A OE2 1 
ATOM   450  N  N   . TYR A 1 85  ? 28.59481  -15.70095 -43.56439 1.000 60.92191  ? 85  TYR A N   1 
ATOM   451  C  CA  . TYR A 1 85  ? 29.08541  -15.95902 -42.21221 1.000 52.03023  ? 85  TYR A CA  1 
ATOM   452  C  C   . TYR A 1 85  ? 28.27324  -15.08618 -41.26242 1.000 52.59809  ? 85  TYR A C   1 
ATOM   453  O  O   . TYR A 1 85  ? 28.65187  -13.95965 -40.93957 1.000 71.20014  ? 85  TYR A O   1 
ATOM   454  C  CB  . TYR A 1 85  ? 30.58198  -15.67831 -42.13955 1.000 49.89422  ? 85  TYR A CB  1 
ATOM   455  C  CG  . TYR A 1 85  ? 31.24667  -15.96347 -40.81189 1.000 58.32361  ? 85  TYR A CG  1 
ATOM   456  C  CD1 . TYR A 1 85  ? 31.03805  -17.16117 -40.14153 1.000 56.57968  ? 85  TYR A CD1 1 
ATOM   457  C  CD2 . TYR A 1 85  ? 32.12023  -15.04280 -40.24834 1.000 66.44543  ? 85  TYR A CD2 1 
ATOM   458  C  CE1 . TYR A 1 85  ? 31.66240  -17.42005 -38.93164 1.000 61.22413  ? 85  TYR A CE1 1 
ATOM   459  C  CE2 . TYR A 1 85  ? 32.74829  -15.29271 -39.04489 1.000 63.87752  ? 85  TYR A CE2 1 
ATOM   460  C  CZ  . TYR A 1 85  ? 32.51736  -16.48064 -38.39004 1.000 62.96328  ? 85  TYR A CZ  1 
ATOM   461  O  OH  . TYR A 1 85  ? 33.14527  -16.72549 -37.19045 1.000 52.82919  ? 85  TYR A OH  1 
ATOM   462  N  N   . MET A 1 86  ? 27.13508  -15.62522 -40.80779 1.000 52.62177  ? 86  MET A N   1 
ATOM   463  C  CA  . MET A 1 86  ? 26.13615  -14.93527 -39.99063 1.000 67.07199  ? 86  MET A CA  1 
ATOM   464  C  C   . MET A 1 86  ? 26.68871  -14.19538 -38.77035 1.000 64.62596  ? 86  MET A C   1 
ATOM   465  O  O   . MET A 1 86  ? 26.13655  -13.14794 -38.40969 1.000 66.39584  ? 86  MET A O   1 
ATOM   466  C  CB  . MET A 1 86  ? 25.05960  -15.92437 -39.53230 1.000 61.20626  ? 86  MET A CB  1 
ATOM   467  C  CG  . MET A 1 86  ? 24.22745  -16.50582 -40.66197 1.000 72.97031  ? 86  MET A CG  1 
ATOM   468  S  SD  . MET A 1 86  ? 23.26757  -15.25237 -41.53366 1.000 85.29008  ? 86  MET A SD  1 
ATOM   469  C  CE  . MET A 1 86  ? 22.09901  -14.76467 -40.26563 1.000 66.19579  ? 86  MET A CE  1 
ATOM   470  N  N   . PRO A 1 87  ? 27.73496  -14.68458 -38.08976 1.000 60.13176  ? 87  PRO A N   1 
ATOM   471  C  CA  . PRO A 1 87  ? 28.27415  -13.91551 -36.95254 1.000 68.62694  ? 87  PRO A CA  1 
ATOM   472  C  C   . PRO A 1 87  ? 28.69180  -12.49098 -37.29271 1.000 66.27678  ? 87  PRO A C   1 
ATOM   473  O  O   . PRO A 1 87  ? 28.72616  -11.64692 -36.38837 1.000 60.39717  ? 87  PRO A O   1 
ATOM   474  C  CB  . PRO A 1 87  ? 29.47712  -14.75648 -36.50570 1.000 66.59246  ? 87  PRO A CB  1 
ATOM   475  C  CG  . PRO A 1 87  ? 29.07830  -16.13606 -36.82120 1.000 66.94296  ? 87  PRO A CG  1 
ATOM   476  C  CD  . PRO A 1 87  ? 28.26915  -16.06245 -38.09080 1.000 55.99153  ? 87  PRO A CD  1 
ATOM   477  N  N   . ALA A 1 88  ? 29.00393  -12.18904 -38.55250 1.000 58.40067  ? 88  ALA A N   1 
ATOM   478  C  CA  . ALA A 1 88  ? 29.46112  -10.86093 -38.94120 1.000 54.33459  ? 88  ALA A CA  1 
ATOM   479  C  C   . ALA A 1 88  ? 28.37392  -10.02279 -39.60585 1.000 59.00068  ? 88  ALA A C   1 
ATOM   480  O  O   . ALA A 1 88  ? 28.67790  -8.96134  -40.16017 1.000 54.51945  ? 88  ALA A O   1 
ATOM   481  C  CB  . ALA A 1 88  ? 30.67056  -10.97159 -39.87154 1.000 52.25741  ? 88  ALA A CB  1 
ATOM   482  N  N   . ALA A 1 89  ? 27.11973  -10.46333 -39.55621 1.000 56.00464  ? 89  ALA A N   1 
ATOM   483  C  CA  . ALA A 1 89  ? 26.02946  -9.74219  -40.19050 1.000 52.47466  ? 89  ALA A CA  1 
ATOM   484  C  C   . ALA A 1 89  ? 25.50028  -8.65080  -39.26192 1.000 59.43492  ? 89  ALA A C   1 
ATOM   485  O  O   . ALA A 1 89  ? 25.99698  -8.44485  -38.15139 1.000 70.66787  ? 89  ALA A O   1 
ATOM   486  C  CB  . ALA A 1 89  ? 24.91676  -10.70909 -40.59119 1.000 55.06536  ? 89  ALA A CB  1 
ATOM   487  N  N   . SER A 1 90  ? 24.48012  -7.93383  -39.73089 1.000 67.84801  ? 90  SER A N   1 
ATOM   488  C  CA  . SER A 1 90  ? 23.80037  -6.95938  -38.88865 1.000 59.56622  ? 90  SER A CA  1 
ATOM   489  C  C   . SER A 1 90  ? 23.20531  -7.64897  -37.66861 1.000 64.13331  ? 90  SER A C   1 
ATOM   490  O  O   . SER A 1 90  ? 22.70558  -8.77304  -37.75609 1.000 71.14285  ? 90  SER A O   1 
ATOM   491  C  CB  . SER A 1 90  ? 22.70051  -6.24881  -39.67970 1.000 59.49342  ? 90  SER A CB  1 
ATOM   492  O  OG  . SER A 1 90  ? 21.83522  -5.53683  -38.81354 1.000 76.24285  ? 90  SER A OG  1 
ATOM   493  N  N   . PHE A 1 91  ? 23.27125  -6.97387  -36.51855 1.000 67.93350  ? 91  PHE A N   1 
ATOM   494  C  CA  . PHE A 1 91  ? 22.78253  -7.58247  -35.28689 1.000 67.03773  ? 91  PHE A CA  1 
ATOM   495  C  C   . PHE A 1 91  ? 21.28423  -7.85231  -35.32881 1.000 68.10195  ? 91  PHE A C   1 
ATOM   496  O  O   . PHE A 1 91  ? 20.79161  -8.66665  -34.54118 1.000 74.75099  ? 91  PHE A O   1 
ATOM   497  C  CB  . PHE A 1 91  ? 23.12330  -6.70272  -34.08327 1.000 59.14652  ? 91  PHE A CB  1 
ATOM   498  C  CG  . PHE A 1 91  ? 22.84576  -7.36027  -32.76190 1.000 66.01034  ? 91  PHE A CG  1 
ATOM   499  C  CD1 . PHE A 1 91  ? 23.62349  -8.42012  -32.32576 1.000 63.76520  ? 91  PHE A CD1 1 
ATOM   500  C  CD2 . PHE A 1 91  ? 21.80648  -6.92296  -31.95791 1.000 68.39051  ? 91  PHE A CD2 1 
ATOM   501  C  CE1 . PHE A 1 91  ? 23.37007  -9.03158  -31.11338 1.000 60.41117  ? 91  PHE A CE1 1 
ATOM   502  C  CE2 . PHE A 1 91  ? 21.54854  -7.53005  -30.74410 1.000 61.02833  ? 91  PHE A CE2 1 
ATOM   503  C  CZ  . PHE A 1 91  ? 22.33174  -8.58568  -30.32169 1.000 58.82865  ? 91  PHE A CZ  1 
ATOM   504  N  N   . TYR A 1 92  ? 20.54777  -7.18611  -36.22002 1.000 60.14218  ? 92  TYR A N   1 
ATOM   505  C  CA  . TYR A 1 92  ? 19.14711  -7.53980  -36.42138 1.000 59.38214  ? 92  TYR A CA  1 
ATOM   506  C  C   . TYR A 1 92  ? 19.01763  -8.95896  -36.95803 1.000 63.96021  ? 92  TYR A C   1 
ATOM   507  O  O   . TYR A 1 92  ? 18.12342  -9.70923  -36.54721 1.000 69.67062  ? 92  TYR A O   1 
ATOM   508  C  CB  . TYR A 1 92  ? 18.48184  -6.54205  -37.36973 1.000 61.72234  ? 92  TYR A CB  1 
ATOM   509  C  CG  . TYR A 1 92  ? 17.02117  -6.82943  -37.64079 1.000 61.00486  ? 92  TYR A CG  1 
ATOM   510  C  CD1 . TYR A 1 92  ? 16.03361  -6.37269  -36.77809 1.000 69.71740  ? 92  TYR A CD1 1 
ATOM   511  C  CD2 . TYR A 1 92  ? 16.62921  -7.55277  -38.76027 1.000 60.62878  ? 92  TYR A CD2 1 
ATOM   512  C  CE1 . TYR A 1 92  ? 14.69715  -6.63061  -37.01946 1.000 68.55609  ? 92  TYR A CE1 1 
ATOM   513  C  CE2 . TYR A 1 92  ? 15.29380  -7.81657  -39.00956 1.000 65.85711  ? 92  TYR A CE2 1 
ATOM   514  C  CZ  . TYR A 1 92  ? 14.33237  -7.35170  -38.13500 1.000 65.09005  ? 92  TYR A CZ  1 
ATOM   515  O  OH  . TYR A 1 92  ? 13.00088  -7.60652  -38.37234 1.000 61.95092  ? 92  TYR A OH  1 
ATOM   516  N  N   . ARG A 1 93  ? 19.90431  -9.34421  -37.87569 1.000 68.73975  ? 93  ARG A N   1 
ATOM   517  C  CA  . ARG A 1 93  ? 19.85127  -10.66094 -38.49749 1.000 67.96766  ? 93  ARG A CA  1 
ATOM   518  C  C   . ARG A 1 93  ? 20.62849  -11.71739 -37.72555 1.000 66.56628  ? 93  ARG A C   1 
ATOM   519  O  O   . ARG A 1 93  ? 20.23842  -12.89010 -37.73355 1.000 79.35435  ? 93  ARG A O   1 
ATOM   520  C  CB  . ARG A 1 93  ? 20.39204  -10.58461 -39.93010 1.000 63.85791  ? 93  ARG A CB  1 
ATOM   521  C  CG  . ARG A 1 93  ? 19.71279  -9.53213  -40.79064 1.000 77.16319  ? 93  ARG A CG  1 
ATOM   522  C  CD  . ARG A 1 93  ? 20.26525  -9.51883  -42.21087 1.000 84.21002  ? 93  ARG A CD  1 
ATOM   523  N  NE  . ARG A 1 93  ? 20.13865  -10.81487 -42.86676 1.000 69.70666  ? 93  ARG A NE  1 
ATOM   524  C  CZ  . ARG A 1 93  ? 21.15444  -11.62641 -43.12849 1.000 73.12860  ? 93  ARG A CZ  1 
ATOM   525  N  NH1 . ARG A 1 93  ? 22.39943  -11.29507 -42.82826 1.000 78.70783  ? 93  ARG A NH1 1 
ATOM   526  N  NH2 . ARG A 1 93  ? 20.91555  -12.79892 -43.71008 1.000 71.16286  ? 93  ARG A NH2 1 
ATOM   527  N  N   . SER A 1 94  ? 21.71375  -11.33291 -37.05439 1.000 55.00627  ? 94  SER A N   1 
ATOM   528  C  CA  . SER A 1 94  ? 22.55086  -12.30813 -36.37194 1.000 53.79248  ? 94  SER A CA  1 
ATOM   529  C  C   . SER A 1 94  ? 22.02652  -12.67979 -34.99252 1.000 63.99078  ? 94  SER A C   1 
ATOM   530  O  O   . SER A 1 94  ? 22.38422  -13.74351 -34.48237 1.000 62.18266  ? 94  SER A O   1 
ATOM   531  C  CB  . SER A 1 94  ? 23.98195  -11.78152 -36.24925 1.000 51.08213  ? 94  SER A CB  1 
ATOM   532  O  OG  . SER A 1 94  ? 24.04631  -10.66994 -35.37146 1.000 82.39453  ? 94  SER A OG  1 
ATOM   533  N  N   . LYS A 1 95  ? 21.18517  -11.84207 -34.38335 1.000 65.20088  ? 95  LYS A N   1 
ATOM   534  C  CA  . LYS A 1 95  ? 20.76635  -12.08210 -33.00405 1.000 61.52699  ? 95  LYS A CA  1 
ATOM   535  C  C   . LYS A 1 95  ? 20.01365  -13.40074 -32.86735 1.000 57.74898  ? 95  LYS A C   1 
ATOM   536  O  O   . LYS A 1 95  ? 20.30803  -14.20444 -31.97569 1.000 64.49920  ? 95  LYS A O   1 
ATOM   537  C  CB  . LYS A 1 95  ? 19.90702  -10.91817 -32.50965 1.000 65.74043  ? 95  LYS A CB  1 
ATOM   538  C  CG  . LYS A 1 95  ? 19.46185  -11.02468 -31.05867 1.000 73.05897  ? 95  LYS A CG  1 
ATOM   539  C  CD  . LYS A 1 95  ? 18.63843  -9.81008  -30.66161 1.000 63.25426  ? 95  LYS A CD  1 
ATOM   540  C  CE  . LYS A 1 95  ? 17.81980  -10.08434 -29.41545 1.000 66.09563  ? 95  LYS A CE  1 
ATOM   541  N  NZ  . LYS A 1 95  ? 16.88271  -8.96500  -29.13367 1.000 61.98313  ? 95  LYS A NZ  1 
ATOM   542  N  N   . ASP A 1 96  ? 19.03086  -13.63922 -33.74035 1.000 64.48433  ? 96  ASP A N   1 
ATOM   543  C  CA  . ASP A 1 96  ? 18.26689  -14.88154 -33.66370 1.000 67.23123  ? 96  ASP A CA  1 
ATOM   544  C  C   . ASP A 1 96  ? 19.15536  -16.09854 -33.89491 1.000 74.80481  ? 96  ASP A C   1 
ATOM   545  O  O   . ASP A 1 96  ? 18.97099  -17.14017 -33.25427 1.000 78.02101  ? 96  ASP A O   1 
ATOM   546  C  CB  . ASP A 1 96  ? 17.11288  -14.84971 -34.66548 1.000 66.52742  ? 96  ASP A CB  1 
ATOM   547  C  CG  . ASP A 1 96  ? 15.96693  -13.97130 -34.20708 1.000 60.76599  ? 96  ASP A CG  1 
ATOM   548  O  OD1 . ASP A 1 96  ? 16.08661  -13.35416 -33.12682 1.000 57.86066  ? 96  ASP A OD1 1 
ATOM   549  O  OD2 . ASP A 1 96  ? 14.94457  -13.90103 -34.92072 1.000 75.86584  ? 96  ASP A OD2 1 
ATOM   550  N  N   . PHE A 1 97  ? 20.11431  -15.99348 -34.81534 1.000 66.39503  ? 97  PHE A N   1 
ATOM   551  C  CA  . PHE A 1 97  ? 21.06025  -17.08587 -35.01974 1.000 67.36960  ? 97  PHE A CA  1 
ATOM   552  C  C   . PHE A 1 97  ? 21.95197  -17.28037 -33.79822 1.000 68.23355  ? 97  PHE A C   1 
ATOM   553  O  O   . PHE A 1 97  ? 22.13989  -18.40794 -33.32652 1.000 69.33391  ? 97  PHE A O   1 
ATOM   554  C  CB  . PHE A 1 97  ? 21.90774  -16.82018 -36.26429 1.000 68.13938  ? 97  PHE A CB  1 
ATOM   555  C  CG  . PHE A 1 97  ? 23.10569  -17.71679 -36.38256 1.000 79.93920  ? 97  PHE A CG  1 
ATOM   556  C  CD1 . PHE A 1 97  ? 22.97995  -18.99904 -36.89135 1.000 85.20982  ? 97  PHE A CD1 1 
ATOM   557  C  CD2 . PHE A 1 97  ? 24.35976  -17.27682 -35.98830 1.000 71.48420  ? 97  PHE A CD2 1 
ATOM   558  C  CE1 . PHE A 1 97  ? 24.08108  -19.82745 -37.00189 1.000 73.44374  ? 97  PHE A CE1 1 
ATOM   559  C  CE2 . PHE A 1 97  ? 25.46348  -18.09958 -36.09522 1.000 66.91756  ? 97  PHE A CE2 1 
ATOM   560  C  CZ  . PHE A 1 97  ? 25.32385  -19.37664 -36.60375 1.000 73.07541  ? 97  PHE A CZ  1 
ATOM   561  N  N   . ILE A 1 98  ? 22.51202  -16.18510 -33.27628 1.000 67.77957  ? 98  ILE A N   1 
ATOM   562  C  CA  . ILE A 1 98  ? 23.42277  -16.25559 -32.13748 1.000 67.87817  ? 98  ILE A CA  1 
ATOM   563  C  C   . ILE A 1 98  ? 22.72034  -16.83862 -30.92046 1.000 65.50629  ? 98  ILE A C   1 
ATOM   564  O  O   . ILE A 1 98  ? 23.33335  -17.56093 -30.12400 1.000 66.87667  ? 98  ILE A O   1 
ATOM   565  C  CB  . ILE A 1 98  ? 24.01073  -14.85818 -31.84808 1.000 69.68145  ? 98  ILE A CB  1 
ATOM   566  C  CG1 . ILE A 1 98  ? 24.96150  -14.43293 -32.96994 1.000 60.01932  ? 98  ILE A CG1 1 
ATOM   567  C  CG2 . ILE A 1 98  ? 24.74033  -14.83557 -30.51697 1.000 79.45448  ? 98  ILE A CG2 1 
ATOM   568  C  CD1 . ILE A 1 98  ? 25.46575  -13.00988 -32.83411 1.000 66.54957  ? 98  ILE A CD1 1 
ATOM   569  N  N   . ASP A 1 99  ? 21.42693  -16.56515 -30.76900 1.000 62.82811  ? 99  ASP A N   1 
ATOM   570  C  CA  . ASP A 1 99  ? 20.65604  -17.08869 -29.64904 1.000 66.16298  ? 99  ASP A CA  1 
ATOM   571  C  C   . ASP A 1 99  ? 20.32964  -18.56972 -29.79581 1.000 75.21462  ? 99  ASP A C   1 
ATOM   572  O  O   . ASP A 1 99  ? 19.62591  -19.11830 -28.94068 1.000 88.95195  ? 99  ASP A O   1 
ATOM   573  C  CB  . ASP A 1 99  ? 19.35892  -16.28932 -29.48223 1.000 68.33732  ? 99  ASP A CB  1 
ATOM   574  C  CG  . ASP A 1 99  ? 19.61270  -14.82992 -29.14851 1.000 78.34241  ? 99  ASP A CG  1 
ATOM   575  O  OD1 . ASP A 1 99  ? 20.79113  -14.44707 -28.97956 1.000 73.19634  ? 99  ASP A OD1 1 
ATOM   576  O  OD2 . ASP A 1 99  ? 18.63144  -14.06311 -29.06100 1.000 78.38866  ? 99  ASP A OD2 1 
ATOM   577  N  N   . THR A 1 100 ? 20.81358  -19.22789 -30.85587 1.000 74.28815  ? 100 THR A N   1 
ATOM   578  C  CA  . THR A 1 100 ? 20.62341  -20.66328 -31.03304 1.000 70.27449  ? 100 THR A CA  1 
ATOM   579  C  C   . THR A 1 100 ? 21.94642  -21.38839 -31.26122 1.000 71.46323  ? 100 THR A C   1 
ATOM   580  O  O   . THR A 1 100 ? 21.95451  -22.48962 -31.81923 1.000 89.86910  ? 100 THR A O   1 
ATOM   581  C  CB  . THR A 1 100 ? 19.66747  -20.95686 -32.19396 1.000 75.44302  ? 100 THR A CB  1 
ATOM   582  O  OG1 . THR A 1 100 ? 20.29039  -20.59763 -33.43343 1.000 69.50464  ? 100 THR A OG1 1 
ATOM   583  C  CG2 . THR A 1 100 ? 18.37052  -20.17476 -32.03955 1.000 78.16875  ? 100 THR A CG2 1 
ATOM   584  N  N   . THR A 1 101 ? 23.06149  -20.80217 -30.84001 1.000 61.17065  ? 101 THR A N   1 
ATOM   585  C  CA  . THR A 1 101 ? 24.36786  -21.43130 -30.97001 1.000 68.70417  ? 101 THR A CA  1 
ATOM   586  C  C   . THR A 1 101 ? 24.81453  -21.97028 -29.61795 1.000 75.57567  ? 101 THR A C   1 
ATOM   587  O  O   . THR A 1 101 ? 24.62318  -21.32078 -28.58599 1.000 67.69523  ? 101 THR A O   1 
ATOM   588  C  CB  . THR A 1 101 ? 25.41185  -20.44784 -31.50375 1.000 63.06282  ? 101 THR A CB  1 
ATOM   589  O  OG1 . THR A 1 101 ? 25.64297  -19.41826 -30.53471 1.000 87.65143  ? 101 THR A OG1 1 
ATOM   590  C  CG2 . THR A 1 101 ? 24.93875  -19.81719 -32.80303 1.000 70.24107  ? 101 THR A CG2 1 
ATOM   591  N  N   . PHE A 1 102 ? 25.41637  -23.16328 -29.63199 1.000 82.55292  ? 102 PHE A N   1 
ATOM   592  C  CA  . PHE A 1 102 ? 25.83511  -23.80292 -28.39085 1.000 76.03007  ? 102 PHE A CA  1 
ATOM   593  C  C   . PHE A 1 102 ? 26.96085  -23.04799 -27.69406 1.000 75.18143  ? 102 PHE A C   1 
ATOM   594  O  O   . PHE A 1 102 ? 27.13666  -23.20747 -26.48151 1.000 86.18062  ? 102 PHE A O   1 
ATOM   595  C  CB  . PHE A 1 102 ? 26.26223  -25.24464 -28.66376 1.000 73.34847  ? 102 PHE A CB  1 
ATOM   596  C  CG  . PHE A 1 102 ? 25.21736  -26.06275 -29.36779 1.000 77.25247  ? 102 PHE A CG  1 
ATOM   597  C  CD1 . PHE A 1 102 ? 24.17116  -26.63244 -28.66074 1.000 70.35261  ? 102 PHE A CD1 1 
ATOM   598  C  CD2 . PHE A 1 102 ? 25.27991  -26.26057 -30.73744 1.000 82.57356  ? 102 PHE A CD2 1 
ATOM   599  C  CE1 . PHE A 1 102 ? 23.20609  -27.38425 -29.30639 1.000 74.46412  ? 102 PHE A CE1 1 
ATOM   600  C  CE2 . PHE A 1 102 ? 24.31827  -27.01212 -31.38971 1.000 84.84771  ? 102 PHE A CE2 1 
ATOM   601  C  CZ  . PHE A 1 102 ? 23.27996  -27.57446 -30.67269 1.000 78.75929  ? 102 PHE A CZ  1 
ATOM   602  N  N   . ALA A 1 103 ? 27.72309  -22.23220 -28.42633 1.000 67.88164  ? 103 ALA A N   1 
ATOM   603  C  CA  . ALA A 1 103 ? 28.80787  -21.47536 -27.81252 1.000 54.27664  ? 103 ALA A CA  1 
ATOM   604  C  C   . ALA A 1 103 ? 28.30502  -20.23905 -27.07946 1.000 62.25182  ? 103 ALA A C   1 
ATOM   605  O  O   . ALA A 1 103 ? 28.90590  -19.83480 -26.07759 1.000 68.83734  ? 103 ALA A O   1 
ATOM   606  C  CB  . ALA A 1 103 ? 29.83801  -21.07395 -28.86687 1.000 39.47196  ? 103 ALA A CB  1 
ATOM   607  N  N   . TYR A 1 104 ? 27.22304  -19.62052 -27.56277 1.000 68.52894  ? 104 TYR A N   1 
ATOM   608  C  CA  . TYR A 1 104 ? 26.69531  -18.43601 -26.89330 1.000 70.75459  ? 104 TYR A CA  1 
ATOM   609  C  C   . TYR A 1 104 ? 26.22043  -18.75335 -25.48366 1.000 72.91831  ? 104 TYR A C   1 
ATOM   610  O  O   . TYR A 1 104 ? 26.29554  -17.89406 -24.59934 1.000 76.92067  ? 104 TYR A O   1 
ATOM   611  C  CB  . TYR A 1 104 ? 25.55963  -17.82032 -27.70939 1.000 65.60816  ? 104 TYR A CB  1 
ATOM   612  C  CG  . TYR A 1 104 ? 24.92253  -16.61933 -27.04416 1.000 60.58098  ? 104 TYR A CG  1 
ATOM   613  C  CD1 . TYR A 1 104 ? 25.68796  -15.52839 -26.65402 1.000 59.99144  ? 104 TYR A CD1 1 
ATOM   614  C  CD2 . TYR A 1 104 ? 23.55496  -16.57588 -26.80945 1.000 60.75863  ? 104 TYR A CD2 1 
ATOM   615  C  CE1 . TYR A 1 104 ? 25.10716  -14.42962 -26.04637 1.000 60.77513  ? 104 TYR A CE1 1 
ATOM   616  C  CE2 . TYR A 1 104 ? 22.96628  -15.48215 -26.20349 1.000 59.99299  ? 104 TYR A CE2 1 
ATOM   617  C  CZ  . TYR A 1 104 ? 23.74513  -14.41251 -25.82299 1.000 59.90969  ? 104 TYR A CZ  1 
ATOM   618  O  OH  . TYR A 1 104 ? 23.15770  -13.32358 -25.21934 1.000 57.70058  ? 104 TYR A OH  1 
ATOM   619  N  N   . LYS A 1 105 ? 25.71812  -19.96971 -25.25691 1.000 63.75647  ? 105 LYS A N   1 
ATOM   620  C  CA  . LYS A 1 105 ? 25.34508  -20.37109 -23.90485 1.000 59.29202  ? 105 LYS A CA  1 
ATOM   621  C  C   . LYS A 1 105 ? 26.56861  -20.52344 -23.01062 1.000 56.17150  ? 105 LYS A C   1 
ATOM   622  O  O   . LYS A 1 105 ? 26.49879  -20.22671 -21.81238 1.000 69.70109  ? 105 LYS A O   1 
ATOM   623  C  CB  . LYS A 1 105 ? 24.54571  -21.67448 -23.94085 1.000 54.57768  ? 105 LYS A CB  1 
ATOM   624  N  N   . ILE A 1 106 ? 27.68945  -20.98860 -23.56827 1.000 57.49702  ? 106 ILE A N   1 
ATOM   625  C  CA  . ILE A 1 106 ? 28.93081  -21.04911 -22.80223 1.000 60.04740  ? 106 ILE A CA  1 
ATOM   626  C  C   . ILE A 1 106 ? 29.35142  -19.65102 -22.37252 1.000 63.53402  ? 106 ILE A C   1 
ATOM   627  O  O   . ILE A 1 106 ? 29.73739  -19.42622 -21.21905 1.000 66.32630  ? 106 ILE A O   1 
ATOM   628  C  CB  . ILE A 1 106 ? 30.03478  -21.74123 -23.62365 1.000 62.84111  ? 106 ILE A CB  1 
ATOM   629  C  CG1 . ILE A 1 106 ? 29.59849  -23.15022 -24.02990 1.000 70.76412  ? 106 ILE A CG1 1 
ATOM   630  C  CG2 . ILE A 1 106 ? 31.33868  -21.77934 -22.83955 1.000 55.97681  ? 106 ILE A CG2 1 
ATOM   631  C  CD1 . ILE A 1 106 ? 29.39166  -24.08683 -22.86311 1.000 63.85860  ? 106 ILE A CD1 1 
ATOM   632  N  N   . ILE A 1 107 ? 29.28077  -18.68873 -23.29434 1.000 70.77978  ? 107 ILE A N   1 
ATOM   633  C  CA  . ILE A 1 107 ? 29.64100  -17.31390 -22.96706 1.000 54.36258  ? 107 ILE A CA  1 
ATOM   634  C  C   . ILE A 1 107 ? 28.62305  -16.70943 -22.00808 1.000 58.53368  ? 107 ILE A C   1 
ATOM   635  O  O   . ILE A 1 107 ? 28.98506  -15.95809 -21.09610 1.000 67.34206  ? 107 ILE A O   1 
ATOM   636  C  CB  . ILE A 1 107 ? 29.78707  -16.48452 -24.25604 1.000 53.86241  ? 107 ILE A CB  1 
ATOM   637  C  CG1 . ILE A 1 107 ? 30.88236  -17.08287 -25.13954 1.000 49.18485  ? 107 ILE A CG1 1 
ATOM   638  C  CG2 . ILE A 1 107 ? 30.10599  -15.03315 -23.93484 1.000 58.67165  ? 107 ILE A CG2 1 
ATOM   639  C  CD1 . ILE A 1 107 ? 31.18669  -16.27525 -26.37631 1.000 68.93950  ? 107 ILE A CD1 1 
ATOM   640  N  N   . GLN A 1 108 ? 27.33707  -17.02699 -22.19576 1.000 58.36490  ? 108 GLN A N   1 
ATOM   641  C  CA  . GLN A 1 108 ? 26.30724  -16.58674 -21.25726 1.000 55.96406  ? 108 GLN A CA  1 
ATOM   642  C  C   . GLN A 1 108 ? 26.65399  -16.98748 -19.83172 1.000 61.71568  ? 108 GLN A C   1 
ATOM   643  O  O   . GLN A 1 108 ? 26.39210  -16.23788 -18.88397 1.000 70.06329  ? 108 GLN A O   1 
ATOM   644  C  CB  . GLN A 1 108 ? 24.94818  -17.17724 -21.64415 1.000 49.43440  ? 108 GLN A CB  1 
ATOM   645  C  CG  . GLN A 1 108 ? 24.13506  -16.36259 -22.63482 1.000 51.91278  ? 108 GLN A CG  1 
ATOM   646  C  CD  . GLN A 1 108 ? 22.71724  -16.88723 -22.77738 1.000 45.70085  ? 108 GLN A CD  1 
ATOM   647  O  OE1 . GLN A 1 108 ? 22.45792  -18.06990 -22.56068 1.000 51.92078  ? 108 GLN A OE1 1 
ATOM   648  N  NE2 . GLN A 1 108 ? 21.78934  -16.00399 -23.12729 1.000 63.91960  ? 108 GLN A NE2 1 
ATOM   649  N  N   . ASP A 1 109 ? 27.25271  -18.16420 -19.66636 1.000 58.09598  ? 109 ASP A N   1 
ATOM   650  C  CA  . ASP A 1 109 ? 27.59939  -18.71264 -18.36486 1.000 54.59217  ? 109 ASP A CA  1 
ATOM   651  C  C   . ASP A 1 109 ? 29.01461  -18.35306 -17.93441 1.000 64.56721  ? 109 ASP A C   1 
ATOM   652  O  O   . ASP A 1 109 ? 29.47201  -18.82796 -16.88971 1.000 78.90860  ? 109 ASP A O   1 
ATOM   653  C  CB  . ASP A 1 109 ? 27.43552  -20.23457 -18.37647 1.000 44.63159  ? 109 ASP A CB  1 
ATOM   654  C  CG  . ASP A 1 109 ? 26.01571  -20.66624 -18.68838 1.000 63.68317  ? 109 ASP A CG  1 
ATOM   655  O  OD1 . ASP A 1 109 ? 25.13270  -19.78781 -18.79656 1.000 68.84988  ? 109 ASP A OD1 1 
ATOM   656  O  OD2 . ASP A 1 109 ? 25.78178  -21.88503 -18.82777 1.000 66.21392  ? 109 ASP A OD2 1 
ATOM   657  N  N   . MET A 1 110 ? 29.71351  -17.53476 -18.70601 1.000 55.70347  ? 110 MET A N   1 
ATOM   658  C  CA  . MET A 1 110 ? 31.11417  -17.27377 -18.39241 1.000 59.27925  ? 110 MET A CA  1 
ATOM   659  C  C   . MET A 1 110 ? 31.23751  -16.03566 -17.51630 1.000 69.85588  ? 110 MET A C   1 
ATOM   660  O  O   . MET A 1 110 ? 30.61749  -15.00928 -17.81684 1.000 77.72329  ? 110 MET A O   1 
ATOM   661  C  CB  . MET A 1 110 ? 31.92876  -17.08525 -19.66359 1.000 49.36424  ? 110 MET A CB  1 
ATOM   662  C  CG  . MET A 1 110 ? 33.41671  -16.86844 -19.42381 1.000 61.83114  ? 110 MET A CG  1 
ATOM   663  S  SD  . MET A 1 110 ? 34.39005  -16.94279 -20.94060 1.000 55.28364  ? 110 MET A SD  1 
ATOM   664  C  CE  . MET A 1 110 ? 33.58125  -15.67203 -21.90353 1.000 73.79670  ? 110 MET A CE  1 
ATOM   665  N  N   . PRO A 1 111 ? 32.01133  -16.08740 -16.43587 1.000 69.09431  ? 111 PRO A N   1 
ATOM   666  C  CA  . PRO A 1 111 ? 32.32591  -14.85152 -15.70887 1.000 71.31373  ? 111 PRO A CA  1 
ATOM   667  C  C   . PRO A 1 111 ? 33.27092  -13.99467 -16.52888 1.000 71.27889  ? 111 PRO A C   1 
ATOM   668  O  O   . PRO A 1 111 ? 34.46243  -14.29546 -16.64812 1.000 70.59014  ? 111 PRO A O   1 
ATOM   669  C  CB  . PRO A 1 111 ? 32.98092  -15.35897 -14.41987 1.000 72.30815  ? 111 PRO A CB  1 
ATOM   670  C  CG  . PRO A 1 111 ? 33.53964  -16.67628 -14.79266 1.000 78.88231  ? 111 PRO A CG  1 
ATOM   671  C  CD  . PRO A 1 111 ? 32.60254  -17.27194 -15.79531 1.000 69.68557  ? 111 PRO A CD  1 
ATOM   672  N  N   . LYS A 1 112 ? 32.74355  -12.91953 -17.10394 1.000 73.36727  ? 112 LYS A N   1 
ATOM   673  C  CA  . LYS A 1 112 ? 33.47540  -12.13047 -18.08524 1.000 75.36028  ? 112 LYS A CA  1 
ATOM   674  C  C   . LYS A 1 112 ? 34.34290  -11.05077 -17.45841 1.000 81.38947  ? 112 LYS A C   1 
ATOM   675  O  O   . LYS A 1 112 ? 35.00933  -10.31292 -18.18954 1.000 79.03152  ? 112 LYS A O   1 
ATOM   676  C  CB  . LYS A 1 112 ? 32.49307  -11.49906 -19.07309 1.000 64.36178  ? 112 LYS A CB  1 
ATOM   677  C  CG  . LYS A 1 112 ? 31.58618  -12.51207 -19.73719 1.000 52.38320  ? 112 LYS A CG  1 
ATOM   678  C  CD  . LYS A 1 112 ? 30.39630  -11.84197 -20.38082 1.000 63.51907  ? 112 LYS A CD  1 
ATOM   679  C  CE  . LYS A 1 112 ? 29.36646  -12.86952 -20.77376 1.000 56.71575  ? 112 LYS A CE  1 
ATOM   680  N  NZ  . LYS A 1 112 ? 28.87988  -13.62147 -19.59031 1.000 60.73200  ? 112 LYS A NZ  1 
ATOM   681  N  N   . GLY A 1 113 ? 34.35508  -10.94158 -16.14558 1.000 67.32445  ? 113 GLY A N   1 
ATOM   682  C  CA  . GLY A 1 113 ? 35.12701  -9.89890  -15.47826 1.000 63.63955  ? 113 GLY A CA  1 
ATOM   683  C  C   . GLY A 1 113 ? 34.30168  -8.62962  -15.30741 1.000 72.07153  ? 113 GLY A C   1 
ATOM   684  O  O   . GLY A 1 113 ? 33.28784  -8.64171  -14.61138 1.000 74.68245  ? 113 GLY A O   1 
ATOM   685  N  N   . GLY A 1 114 ? 34.73154  -7.55643  -15.94961 1.000 66.55761  ? 114 GLY A N   1 
ATOM   686  C  CA  . GLY A 1 114 ? 34.06794  -6.27011  -15.81303 1.000 61.16316  ? 114 GLY A CA  1 
ATOM   687  C  C   . GLY A 1 114 ? 33.72181  -5.65131  -17.14873 1.000 56.17519  ? 114 GLY A C   1 
ATOM   688  O  O   . GLY A 1 114 ? 34.45350  -5.80369  -18.12705 1.000 55.09990  ? 114 GLY A O   1 
ATOM   689  N  N   . ALA A 1 115 ? 32.58730  -4.95531  -17.17929 1.000 57.49370  ? 115 ALA A N   1 
ATOM   690  C  CA  . ALA A 1 115 ? 32.18437  -4.13367  -18.31480 1.000 66.98566  ? 115 ALA A CA  1 
ATOM   691  C  C   . ALA A 1 115 ? 32.54811  -2.68935  -17.98529 1.000 60.51619  ? 115 ALA A C   1 
ATOM   692  O  O   . ALA A 1 115 ? 31.94504  -2.07870  -17.09684 1.000 63.00088  ? 115 ALA A O   1 
ATOM   693  C  CB  . ALA A 1 115 ? 30.69116  -4.28416  -18.59652 1.000 52.24065  ? 115 ALA A CB  1 
ATOM   694  N  N   . LEU A 1 116 ? 33.53324  -2.14542  -18.69815 1.000 54.57670  ? 116 LEU A N   1 
ATOM   695  C  CA  . LEU A 1 116 ? 34.15619  -0.88196  -18.32381 1.000 60.78425  ? 116 LEU A CA  1 
ATOM   696  C  C   . LEU A 1 116 ? 33.68812  0.31245   -19.14823 1.000 72.89552  ? 116 LEU A C   1 
ATOM   697  O  O   . LEU A 1 116 ? 34.23222  1.40798   -18.97946 1.000 81.45174  ? 116 LEU A O   1 
ATOM   698  C  CB  . LEU A 1 116 ? 35.67968  -1.00517  -18.43132 1.000 62.18593  ? 116 LEU A CB  1 
ATOM   699  C  CG  . LEU A 1 116 ? 36.33420  -2.10656  -17.59704 1.000 51.58338  ? 116 LEU A CG  1 
ATOM   700  C  CD1 . LEU A 1 116 ? 37.84717  -2.05431  -17.73781 1.000 55.98837  ? 116 LEU A CD1 1 
ATOM   701  C  CD2 . LEU A 1 116 ? 35.92226  -1.98380  -16.13981 1.000 55.52647  ? 116 LEU A CD2 1 
ATOM   702  N  N   . HIS A 1 117 ? 32.70195  0.13990   -20.02894 1.000 67.49198  ? 117 HIS A N   1 
ATOM   703  C  CA  . HIS A 1 117 ? 32.20999  1.23039   -20.87811 1.000 68.06676  ? 117 HIS A CA  1 
ATOM   704  C  C   . HIS A 1 117 ? 30.69098  1.08951   -20.95499 1.000 73.51794  ? 117 HIS A C   1 
ATOM   705  O  O   . HIS A 1 117 ? 30.16946  0.32368   -21.76388 1.000 73.71512  ? 117 HIS A O   1 
ATOM   706  C  CB  . HIS A 1 117 ? 32.86475  1.18431   -22.25532 1.000 66.69900  ? 117 HIS A CB  1 
ATOM   707  C  CG  . HIS A 1 117 ? 32.51854  2.34123   -23.14200 1.000 72.96880  ? 117 HIS A CG  1 
ATOM   708  N  ND1 . HIS A 1 117 ? 33.45423  2.97702   -23.92961 1.000 78.66891  ? 117 HIS A ND1 1 
ATOM   709  C  CD2 . HIS A 1 117 ? 31.34082  2.96433   -23.38170 1.000 77.39091  ? 117 HIS A CD2 1 
ATOM   710  C  CE1 . HIS A 1 117 ? 32.87028  3.94912   -24.60679 1.000 67.41019  ? 117 HIS A CE1 1 
ATOM   711  N  NE2 . HIS A 1 117 ? 31.58751  3.96159   -24.29333 1.000 78.03294  ? 117 HIS A NE2 1 
ATOM   712  N  N   . LEU A 1 118 ? 29.98000  1.81848   -20.10172 1.000 65.12516  ? 118 LEU A N   1 
ATOM   713  C  CA  . LEU A 1 118 ? 28.52642  1.75278   -20.09902 1.000 56.77226  ? 118 LEU A CA  1 
ATOM   714  C  C   . LEU A 1 118 ? 27.93847  3.14791   -19.96216 1.000 65.53792  ? 118 LEU A C   1 
ATOM   715  O  O   . LEU A 1 118 ? 28.55949  4.04986   -19.39583 1.000 76.84090  ? 118 LEU A O   1 
ATOM   716  C  CB  . LEU A 1 118 ? 28.00420  0.85852   -18.96807 1.000 59.86929  ? 118 LEU A CB  1 
ATOM   717  C  CG  . LEU A 1 118 ? 28.23928  -0.64399  -19.12370 1.000 67.11143  ? 118 LEU A CG  1 
ATOM   718  C  CD1 . LEU A 1 118 ? 27.84732  -1.36988  -17.84828 1.000 65.62067  ? 118 LEU A CD1 1 
ATOM   719  C  CD2 . LEU A 1 118 ? 27.45854  -1.17900  -20.31229 1.000 62.14975  ? 118 LEU A CD2 1 
ATOM   720  N  N   . HIS A 1 119 ? 26.72945  3.31311   -20.49026 1.000 62.68552  ? 119 HIS A N   1 
ATOM   721  C  CA  . HIS A 1 119 ? 25.95170  4.53338   -20.33369 1.000 68.77021  ? 119 HIS A CA  1 
ATOM   722  C  C   . HIS A 1 119 ? 24.66792  4.18438   -19.59755 1.000 68.35198  ? 119 HIS A C   1 
ATOM   723  O  O   . HIS A 1 119 ? 23.95369  3.25884   -19.99492 1.000 58.50394  ? 119 HIS A O   1 
ATOM   724  C  CB  . HIS A 1 119 ? 25.65690  5.17619   -21.69050 1.000 67.66063  ? 119 HIS A CB  1 
ATOM   725  C  CG  . HIS A 1 119 ? 26.87535  5.69724   -22.38728 1.000 77.66569  ? 119 HIS A CG  1 
ATOM   726  N  ND1 . HIS A 1 119 ? 27.89419  6.34473   -21.72215 1.000 82.42077  ? 119 HIS A ND1 1 
ATOM   727  C  CD2 . HIS A 1 119 ? 27.23700  5.66774   -23.69147 1.000 83.10071  ? 119 HIS A CD2 1 
ATOM   728  C  CE1 . HIS A 1 119 ? 28.83166  6.69011   -22.58610 1.000 76.70519  ? 119 HIS A CE1 1 
ATOM   729  N  NE2 . HIS A 1 119 ? 28.45692  6.29177   -23.78815 1.000 79.11440  ? 119 HIS A NE2 1 
ATOM   730  N  N   . ASP A 1 120 ? 24.37806  4.93175   -18.53061 1.000 67.34531  ? 120 ASP A N   1 
ATOM   731  C  CA  . ASP A 1 120 ? 23.38846  4.48552   -17.54903 1.000 57.48984  ? 120 ASP A CA  1 
ATOM   732  C  C   . ASP A 1 120 ? 21.98980  4.35565   -18.14702 1.000 66.81614  ? 120 ASP A C   1 
ATOM   733  O  O   . ASP A 1 120 ? 21.28780  3.37394   -17.87786 1.000 67.42092  ? 120 ASP A O   1 
ATOM   734  C  CB  . ASP A 1 120 ? 23.37971  5.43099   -16.34026 1.000 60.87522  ? 120 ASP A CB  1 
ATOM   735  C  CG  . ASP A 1 120 ? 23.06127  6.87536   -16.71265 1.000 78.03217  ? 120 ASP A CG  1 
ATOM   736  O  OD1 . ASP A 1 120 ? 23.25393  7.27383   -17.87872 1.000 82.53212  ? 120 ASP A OD1 1 
ATOM   737  O  OD2 . ASP A 1 120 ? 22.62269  7.62622   -15.81111 1.000 73.68440  ? 120 ASP A OD2 1 
ATOM   738  N  N   . THR A 1 121 ? 21.56626  5.31895   -18.96565 1.000 59.40794  ? 121 THR A N   1 
ATOM   739  C  CA  . THR A 1 121 ? 20.18366  5.36762   -19.43715 1.000 52.58492  ? 121 THR A CA  1 
ATOM   740  C  C   . THR A 1 121 ? 19.89029  4.34937   -20.54408 1.000 61.78256  ? 121 THR A C   1 
ATOM   741  O  O   . THR A 1 121 ? 18.78372  4.36901   -21.09423 1.000 58.27488  ? 121 THR A O   1 
ATOM   742  C  CB  . THR A 1 121 ? 19.83671  6.77467   -19.92138 1.000 57.58343  ? 121 THR A CB  1 
ATOM   743  O  OG1 . THR A 1 121 ? 20.83933  7.24001   -20.83774 1.000 70.15704  ? 121 THR A OG1 1 
ATOM   744  C  CG2 . THR A 1 121 ? 19.74559  7.73782   -18.74375 1.000 68.46554  ? 121 THR A CG2 1 
ATOM   745  N  N   . ALA A 1 122 ? 20.83417  3.47828   -20.88389 1.000 59.25961  ? 122 ALA A N   1 
ATOM   746  C  CA  . ALA A 1 122 ? 20.58260  2.46122   -21.88892 1.000 54.05372  ? 122 ALA A CA  1 
ATOM   747  C  C   . ALA A 1 122 ? 21.25913  1.13902   -21.54667 1.000 67.65448  ? 122 ALA A C   1 
ATOM   748  O  O   . ALA A 1 122 ? 21.56794  0.34788   -22.44665 1.000 68.99237  ? 122 ALA A O   1 
ATOM   749  C  CB  . ALA A 1 122 ? 21.02636  2.94243   -23.27261 1.000 53.47372  ? 122 ALA A CB  1 
ATOM   750  N  N   . SER A 1 123 ? 21.52163  0.89059   -20.26453 1.000 59.55286  ? 123 SER A N   1 
ATOM   751  C  CA  . SER A 1 123 ? 22.17031  -0.34080  -19.83611 1.000 53.98413  ? 123 SER A CA  1 
ATOM   752  C  C   . SER A 1 123 ? 21.19423  -1.34539  -19.23804 1.000 57.45157  ? 123 SER A C   1 
ATOM   753  O  O   . SER A 1 123 ? 21.62771  -2.33761  -18.64309 1.000 53.23389  ? 123 SER A O   1 
ATOM   754  C  CB  . SER A 1 123 ? 23.28770  -0.03505  -18.83905 1.000 64.49114  ? 123 SER A CB  1 
ATOM   755  O  OG  . SER A 1 123 ? 24.38407  0.59047   -19.47973 1.000 66.98551  ? 123 SER A OG  1 
ATOM   756  N  N   . ALA A 1 124 ? 19.89167  -1.10978  -19.37558 1.000 58.59046  ? 124 ALA A N   1 
ATOM   757  C  CA  . ALA A 1 124 ? 18.87689  -2.05141  -18.92737 1.000 61.38524  ? 124 ALA A CA  1 
ATOM   758  C  C   . ALA A 1 124 ? 17.79340  -2.13252  -19.99349 1.000 69.01219  ? 124 ALA A C   1 
ATOM   759  O  O   . ALA A 1 124 ? 17.76721  -1.34593  -20.94461 1.000 69.43863  ? 124 ALA A O   1 
ATOM   760  C  CB  . ALA A 1 124 ? 18.29001  -1.65740  -17.56670 1.000 60.01396  ? 124 ALA A CB  1 
ATOM   761  N  N   . ARG A 1 125 ? 16.88693  -3.08862  -19.82275 1.000 52.95122  ? 125 ARG A N   1 
ATOM   762  C  CA  . ARG A 1 125 ? 16.00968  -3.51025  -20.90418 1.000 60.84577  ? 125 ARG A CA  1 
ATOM   763  C  C   . ARG A 1 125 ? 14.75610  -2.65107  -21.00312 1.000 62.42811  ? 125 ARG A C   1 
ATOM   764  O  O   . ARG A 1 125 ? 14.21100  -2.18201  -20.00119 1.000 71.85594  ? 125 ARG A O   1 
ATOM   765  C  CB  . ARG A 1 125 ? 15.64491  -4.98238  -20.72342 1.000 74.68365  ? 125 ARG A CB  1 
ATOM   766  C  CG  . ARG A 1 125 ? 16.89544  -5.80154  -20.51344 1.000 80.92845  ? 125 ARG A CG  1 
ATOM   767  C  CD  . ARG A 1 125 ? 16.76949  -7.26697  -20.84292 1.000 89.42723  ? 125 ARG A CD  1 
ATOM   768  N  NE  . ARG A 1 125 ? 18.10252  -7.85467  -20.90836 1.000 102.89372 ? 125 ARG A NE  1 
ATOM   769  C  CZ  . ARG A 1 125 ? 18.35521  -9.14257  -21.09095 1.000 107.91757 ? 125 ARG A CZ  1 
ATOM   770  N  NH1 . ARG A 1 125 ? 17.38048  -10.03146 -21.18740 1.000 119.49861 ? 125 ARG A NH1 1 
ATOM   771  N  NH2 . ARG A 1 125 ? 19.61859  -9.54827  -21.18275 1.000 95.23431  ? 125 ARG A NH2 1 
ATOM   772  N  N   . ILE A 1 126 ? 14.30497  -2.45996  -22.24632 1.000 66.53770  ? 126 ILE A N   1 
ATOM   773  C  CA  . ILE A 1 126 ? 13.11976  -1.65925  -22.53116 1.000 68.99618  ? 126 ILE A CA  1 
ATOM   774  C  C   . ILE A 1 126 ? 11.86608  -2.30578  -21.95623 1.000 78.67209  ? 126 ILE A C   1 
ATOM   775  O  O   . ILE A 1 126 ? 10.92329  -1.60677  -21.56301 1.000 73.79938  ? 126 ILE A O   1 
ATOM   776  C  CB  . ILE A 1 126 ? 13.01015  -1.44653  -24.05215 1.000 73.81082  ? 126 ILE A CB  1 
ATOM   777  C  CG1 . ILE A 1 126 ? 14.21319  -0.65059  -24.56405 1.000 74.66717  ? 126 ILE A CG1 1 
ATOM   778  C  CG2 . ILE A 1 126 ? 11.69799  -0.77743  -24.41931 1.000 73.88747  ? 126 ILE A CG2 1 
ATOM   779  C  CD1 . ILE A 1 126 ? 14.16314  -0.35716  -26.04387 1.000 64.75662  ? 126 ILE A CD1 1 
ATOM   780  N  N   . ASP A 1 127 ? 11.83520  -3.63959  -21.88294 1.000 76.11449  ? 127 ASP A N   1 
ATOM   781  C  CA  . ASP A 1 127 ? 10.64827  -4.33341  -21.39210 1.000 69.08732  ? 127 ASP A CA  1 
ATOM   782  C  C   . ASP A 1 127 ? 10.30877  -3.93531  -19.96136 1.000 72.82283  ? 127 ASP A C   1 
ATOM   783  O  O   . ASP A 1 127 ? 9.13302   -3.93805  -19.58429 1.000 76.85898  ? 127 ASP A O   1 
ATOM   784  C  CB  . ASP A 1 127 ? 10.84408  -5.84588  -21.49096 1.000 79.56193  ? 127 ASP A CB  1 
ATOM   785  C  CG  . ASP A 1 127 ? 11.03985  -6.31689  -22.92028 1.000 90.59203  ? 127 ASP A CG  1 
ATOM   786  O  OD1 . ASP A 1 127 ? 12.04938  -5.93046  -23.54684 1.000 86.06301  ? 127 ASP A OD1 1 
ATOM   787  O  OD2 . ASP A 1 127 ? 10.18158  -7.07411  -23.41937 1.000 92.52611  ? 127 ASP A OD2 1 
ATOM   788  N  N   . TRP A 1 128 ? 11.31603  -3.59954  -19.14962 1.000 74.66362  ? 128 TRP A N   1 
ATOM   789  C  CA  . TRP A 1 128 ? 11.04073  -3.13329  -17.79383 1.000 64.65994  ? 128 TRP A CA  1 
ATOM   790  C  C   . TRP A 1 128 ? 10.34380  -1.77902  -17.80713 1.000 69.51647  ? 128 TRP A C   1 
ATOM   791  O  O   . TRP A 1 128 ? 9.48273   -1.50872  -16.96231 1.000 71.21568  ? 128 TRP A O   1 
ATOM   792  C  CB  . TRP A 1 128 ? 12.33141  -3.06104  -16.98032 1.000 50.38727  ? 128 TRP A CB  1 
ATOM   793  C  CG  . TRP A 1 128 ? 12.11146  -2.63744  -15.56014 1.000 70.04560  ? 128 TRP A CG  1 
ATOM   794  C  CD1 . TRP A 1 128 ? 11.75402  -3.43645  -14.51399 1.000 69.88338  ? 128 TRP A CD1 1 
ATOM   795  C  CD2 . TRP A 1 128 ? 12.23338  -1.31171  -15.02843 1.000 83.22280  ? 128 TRP A CD2 1 
ATOM   796  N  NE1 . TRP A 1 128 ? 11.64530  -2.69290  -13.36457 1.000 57.90696  ? 128 TRP A NE1 1 
ATOM   797  C  CE2 . TRP A 1 128 ? 11.93487  -1.38517  -13.65298 1.000 78.92686  ? 128 TRP A CE2 1 
ATOM   798  C  CE3 . TRP A 1 128 ? 12.56562  -0.07067  -15.58140 1.000 71.43691  ? 128 TRP A CE3 1 
ATOM   799  C  CZ2 . TRP A 1 128 ? 11.95873  -0.26650  -12.82315 1.000 75.51674  ? 128 TRP A CZ2 1 
ATOM   800  C  CZ3 . TRP A 1 128 ? 12.58922  1.03948   -14.75486 1.000 66.75519  ? 128 TRP A CZ3 1 
ATOM   801  C  CH2 . TRP A 1 128 ? 12.28790  0.93341   -13.39095 1.000 69.07274  ? 128 TRP A CH2 1 
ATOM   802  N  N   . ILE A 1 129 ? 10.71071  -0.90973  -18.75065 1.000 69.52812  ? 129 ILE A N   1 
ATOM   803  C  CA  . ILE A 1 129 ? 10.07273  0.39931   -18.83321 1.000 73.14527  ? 129 ILE A CA  1 
ATOM   804  C  C   . ILE A 1 129 ? 8.63673   0.26854   -19.33009 1.000 72.73490  ? 129 ILE A C   1 
ATOM   805  O  O   . ILE A 1 129 ? 7.75341   1.02446   -18.90609 1.000 77.61496  ? 129 ILE A O   1 
ATOM   806  C  CB  . ILE A 1 129 ? 10.91743  1.33662   -19.71650 1.000 58.06779  ? 129 ILE A CB  1 
ATOM   807  C  CG1 . ILE A 1 129 ? 12.30933  1.50743   -19.10455 1.000 45.83255  ? 129 ILE A CG1 1 
ATOM   808  C  CG2 . ILE A 1 129 ? 10.24389  2.68826   -19.86786 1.000 42.71557  ? 129 ILE A CG2 1 
ATOM   809  C  CD1 . ILE A 1 129 ? 13.26023  2.33121   -19.93854 1.000 57.75754  ? 129 ILE A CD1 1 
ATOM   810  N  N   . VAL A 1 130 ? 8.37435   -0.69004  -20.21899 1.000 61.82086  ? 130 VAL A N   1 
ATOM   811  C  CA  . VAL A 1 130 ? 7.01684   -0.90447  -20.70916 1.000 63.23853  ? 130 VAL A CA  1 
ATOM   812  C  C   . VAL A 1 130 ? 6.14962   -1.59381  -19.65811 1.000 77.78042  ? 130 VAL A C   1 
ATOM   813  O  O   . VAL A 1 130 ? 4.96420   -1.27772  -19.51369 1.000 82.17654  ? 130 VAL A O   1 
ATOM   814  C  CB  . VAL A 1 130 ? 7.05032   -1.69928  -22.02637 1.000 62.41269  ? 130 VAL A CB  1 
ATOM   815  C  CG1 . VAL A 1 130 ? 5.63909   -1.99802  -22.49290 1.000 64.36003  ? 130 VAL A CG1 1 
ATOM   816  C  CG2 . VAL A 1 130 ? 7.81306   -0.92752  -23.09142 1.000 68.84817  ? 130 VAL A CG2 1 
ATOM   817  N  N   . SER A 1 131 ? 6.70852   -2.54800  -18.91496 1.000 79.52282  ? 131 SER A N   1 
ATOM   818  C  CA  . SER A 1 131 ? 5.89787   -3.35224  -18.00650 1.000 71.96067  ? 131 SER A CA  1 
ATOM   819  C  C   . SER A 1 131 ? 5.82765   -2.77460  -16.59693 1.000 81.85670  ? 131 SER A C   1 
ATOM   820  O  O   . SER A 1 131 ? 4.78268   -2.86036  -15.94554 1.000 84.82769  ? 131 SER A O   1 
ATOM   821  C  CB  . SER A 1 131 ? 6.44204   -4.78122  -17.94386 1.000 74.69233  ? 131 SER A CB  1 
ATOM   822  O  OG  . SER A 1 131 ? 7.72885   -4.80103  -17.35431 1.000 83.68599  ? 131 SER A OG  1 
ATOM   823  N  N   . ASN A 1 132 ? 6.91543   -2.19466  -16.09978 1.000 84.99194  ? 132 ASN A N   1 
ATOM   824  C  CA  . ASN A 1 132 ? 6.93022   -1.62068  -14.76270 1.000 85.75179  ? 132 ASN A CA  1 
ATOM   825  C  C   . ASN A 1 132 ? 6.64539   -0.12100  -14.75860 1.000 79.75796  ? 132 ASN A C   1 
ATOM   826  O  O   . ASN A 1 132 ? 5.74649   0.33543   -14.04580 1.000 78.72282  ? 132 ASN A O   1 
ATOM   827  C  CB  . ASN A 1 132 ? 8.28201   -1.91363  -14.11830 1.000 79.54492  ? 132 ASN A CB  1 
ATOM   828  C  CG  . ASN A 1 132 ? 8.34392   -1.48007  -12.68715 1.000 91.76494  ? 132 ASN A CG  1 
ATOM   829  O  OD1 . ASN A 1 132 ? 8.05093   -0.33003  -12.33385 1.000 96.27231  ? 132 ASN A OD1 1 
ATOM   830  N  ND2 . ASN A 1 132 ? 8.76197   -2.40223  -11.83230 1.000 106.95518 ? 132 ASN A ND2 1 
ATOM   831  N  N   . ALA A 1 133 ? 7.42564   0.66356   -15.51186 1.000 76.39044  ? 133 ALA A N   1 
ATOM   832  C  CA  . ALA A 1 133 ? 7.35856   2.11891   -15.38487 1.000 71.56967  ? 133 ALA A CA  1 
ATOM   833  C  C   . ALA A 1 133 ? 6.05901   2.69015   -15.94901 1.000 72.48200  ? 133 ALA A C   1 
ATOM   834  O  O   . ALA A 1 133 ? 5.41045   3.52158   -15.30329 1.000 74.34544  ? 133 ALA A O   1 
ATOM   835  C  CB  . ALA A 1 133 ? 8.56275   2.76411   -16.06754 1.000 54.75085  ? 133 ALA A CB  1 
ATOM   836  N  N   . THR A 1 134 ? 5.66768   2.28222   -17.15985 1.000 75.13198  ? 134 THR A N   1 
ATOM   837  C  CA  . THR A 1 134 ? 4.47744   2.85926   -17.78334 1.000 69.82381  ? 134 THR A CA  1 
ATOM   838  C  C   . THR A 1 134 ? 3.17811   2.26757   -17.24158 1.000 69.97593  ? 134 THR A C   1 
ATOM   839  O  O   . THR A 1 134 ? 2.10790   2.53043   -17.80322 1.000 78.23545  ? 134 THR A O   1 
ATOM   840  C  CB  . THR A 1 134 ? 4.52016   2.70450   -19.30787 1.000 67.57211  ? 134 THR A CB  1 
ATOM   841  O  OG1 . THR A 1 134 ? 4.48795   1.31844   -19.65614 1.000 77.06959  ? 134 THR A OG1 1 
ATOM   842  C  CG2 . THR A 1 134 ? 5.77831   3.34115   -19.87913 1.000 68.29964  ? 134 THR A CG2 1 
ATOM   843  N  N   . TYR A 1 135 ? 3.25436   1.46793   -16.18128 1.000 79.24022  ? 135 TYR A N   1 
ATOM   844  C  CA  . TYR A 1 135 ? 2.08888   1.05164   -15.41794 1.000 86.14245  ? 135 TYR A CA  1 
ATOM   845  C  C   . TYR A 1 135 ? 1.94118   1.82708   -14.11703 1.000 89.80397  ? 135 TYR A C   1 
ATOM   846  O  O   . TYR A 1 135 ? 0.95769   1.62645   -13.39740 1.000 99.90554  ? 135 TYR A O   1 
ATOM   847  C  CB  . TYR A 1 135 ? 2.15662   -0.44940  -15.11535 1.000 87.59679  ? 135 TYR A CB  1 
ATOM   848  C  CG  . TYR A 1 135 ? 1.53541   -1.31266  -16.18558 1.000 77.55117  ? 135 TYR A CG  1 
ATOM   849  C  CD1 . TYR A 1 135 ? 2.26973   -1.72515  -17.28889 1.000 79.30196  ? 135 TYR A CD1 1 
ATOM   850  C  CD2 . TYR A 1 135 ? 0.20948   -1.71345  -16.09348 1.000 70.20874  ? 135 TYR A CD2 1 
ATOM   851  C  CE1 . TYR A 1 135 ? 1.70174   -2.51320  -18.26823 1.000 78.16089  ? 135 TYR A CE1 1 
ATOM   852  C  CE2 . TYR A 1 135 ? -0.36687  -2.49874  -17.06596 1.000 71.11803  ? 135 TYR A CE2 1 
ATOM   853  C  CZ  . TYR A 1 135 ? 0.38200   -2.89556  -18.15005 1.000 80.34868  ? 135 TYR A CZ  1 
ATOM   854  O  OH  . TYR A 1 135 ? -0.19647  -3.67982  -19.11607 1.000 80.91338  ? 135 TYR A OH  1 
ATOM   855  N  N   . ARG A 1 136 ? 2.89066   2.70188   -13.79972 1.000 78.70368  ? 136 ARG A N   1 
ATOM   856  C  CA  . ARG A 1 136 ? 2.80242   3.52620   -12.60886 1.000 79.11320  ? 136 ARG A CA  1 
ATOM   857  C  C   . ARG A 1 136 ? 1.80304   4.66017   -12.82090 1.000 84.54818  ? 136 ARG A C   1 
ATOM   858  O  O   . ARG A 1 136 ? 1.33707   4.92071   -13.93402 1.000 85.88329  ? 136 ARG A O   1 
ATOM   859  C  CB  . ARG A 1 136 ? 4.17323   4.08851   -12.24283 1.000 76.48977  ? 136 ARG A CB  1 
ATOM   860  C  CG  . ARG A 1 136 ? 5.26051   3.03480   -12.15175 1.000 71.86021  ? 136 ARG A CG  1 
ATOM   861  C  CD  . ARG A 1 136 ? 6.47147   3.53981   -11.39342 1.000 68.91160  ? 136 ARG A CD  1 
ATOM   862  N  NE  . ARG A 1 136 ? 7.51986   2.53000   -11.34221 1.000 71.00266  ? 136 ARG A NE  1 
ATOM   863  C  CZ  . ARG A 1 136 ? 8.57553   2.58457   -10.54270 1.000 86.08486  ? 136 ARG A CZ  1 
ATOM   864  N  NH1 . ARG A 1 136 ? 8.76006   3.59529   -9.70906  1.000 80.60335  ? 136 ARG A NH1 1 
ATOM   865  N  NH2 . ARG A 1 136 ? 9.46465   1.59636   -10.57573 1.000 79.92567  ? 136 ARG A NH2 1 
ATOM   866  N  N   . ASP A 1 137 ? 1.46879   5.33734   -11.72791 1.000 84.04279  ? 137 ASP A N   1 
ATOM   867  C  CA  . ASP A 1 137 ? 0.56460   6.47259   -11.79909 1.000 86.52028  ? 137 ASP A CA  1 
ATOM   868  C  C   . ASP A 1 137 ? 1.30632   7.70538   -12.30081 1.000 83.07040  ? 137 ASP A C   1 
ATOM   869  O  O   . ASP A 1 137 ? 2.53190   7.80606   -12.19092 1.000 87.60358  ? 137 ASP A O   1 
ATOM   870  C  CB  . ASP A 1 137 ? -0.06210  6.74830   -10.43080 1.000 81.68506  ? 137 ASP A CB  1 
ATOM   871  C  CG  . ASP A 1 137 ? -1.00161  5.64051   -9.98381  1.000 105.04019 ? 137 ASP A CG  1 
ATOM   872  O  OD1 . ASP A 1 137 ? -1.16756  4.65134   -10.73061 1.000 103.28851 ? 137 ASP A OD1 1 
ATOM   873  O  OD2 . ASP A 1 137 ? -1.57663  5.76040   -8.88269  1.000 118.40516 ? 137 ASP A OD2 1 
ATOM   874  N  N   . HIS A 1 138 ? 0.54440   8.63528   -12.88171 1.000 71.90825  ? 138 HIS A N   1 
ATOM   875  C  CA  . HIS A 1 138 ? 1.05370   9.91952   -13.36707 1.000 75.18675  ? 138 HIS A CA  1 
ATOM   876  C  C   . HIS A 1 138 ? 1.96547   9.76482   -14.58169 1.000 78.09437  ? 138 HIS A C   1 
ATOM   877  O  O   . HIS A 1 138 ? 2.89111   10.55644  -14.76997 1.000 78.48317  ? 138 HIS A O   1 
ATOM   878  C  CB  . HIS A 1 138 ? 1.78809   10.68776  -12.25992 1.000 71.00663  ? 138 HIS A CB  1 
ATOM   879  C  CG  . HIS A 1 138 ? 1.04454   10.73453  -10.96245 1.000 84.30456  ? 138 HIS A CG  1 
ATOM   880  N  ND1 . HIS A 1 138 ? -0.33160  10.70446  -10.89129 1.000 91.64397  ? 138 HIS A ND1 1 
ATOM   881  C  CD2 . HIS A 1 138 ? 1.48631   10.79926  -9.68446  1.000 80.78742  ? 138 HIS A CD2 1 
ATOM   882  C  CE1 . HIS A 1 138 ? -0.70575  10.75503  -9.62579  1.000 92.44667  ? 138 HIS A CE1 1 
ATOM   883  N  NE2 . HIS A 1 138 ? 0.37813   10.81349  -8.87338  1.000 83.93397  ? 138 HIS A NE2 1 
ATOM   884  N  N   . VAL A 1 139 ? 1.72125   8.76214   -15.42077 1.000 83.79890  ? 139 VAL A N   1 
ATOM   885  C  CA  . VAL A 1 139 ? 2.51512   8.53432   -16.62431 1.000 81.04672  ? 139 VAL A CA  1 
ATOM   886  C  C   . VAL A 1 139 ? 1.67021   8.90913   -17.83427 1.000 72.19190  ? 139 VAL A C   1 
ATOM   887  O  O   . VAL A 1 139 ? 0.63329   8.28610   -18.09431 1.000 69.15418  ? 139 VAL A O   1 
ATOM   888  C  CB  . VAL A 1 139 ? 3.00224   7.08000   -16.72222 1.000 74.42129  ? 139 VAL A CB  1 
ATOM   889  C  CG1 . VAL A 1 139 ? 3.75471   6.86083   -18.02874 1.000 61.04061  ? 139 VAL A CG1 1 
ATOM   890  C  CG2 . VAL A 1 139 ? 3.88443   6.72747   -15.53205 1.000 69.24723  ? 139 VAL A CG2 1 
ATOM   891  N  N   . TYR A 1 140 ? 2.11912   9.91678   -18.57726 1.000 83.25288  ? 140 TYR A N   1 
ATOM   892  C  CA  . TYR A 1 140 ? 1.45617   10.37215  -19.78897 1.000 84.74383  ? 140 TYR A CA  1 
ATOM   893  C  C   . TYR A 1 140 ? 2.25665   9.94270   -21.01312 1.000 85.18745  ? 140 TYR A C   1 
ATOM   894  O  O   . TYR A 1 140 ? 3.44576   9.62384   -20.92810 1.000 73.97663  ? 140 TYR A O   1 
ATOM   895  C  CB  . TYR A 1 140 ? 1.28361   11.89805  -19.79369 1.000 75.83874  ? 140 TYR A CB  1 
ATOM   896  C  CG  . TYR A 1 140 ? 0.44531   12.45685  -18.66090 1.000 83.85407  ? 140 TYR A CG  1 
ATOM   897  C  CD1 . TYR A 1 140 ? 1.01329   12.74420  -17.42572 1.000 88.19551  ? 140 TYR A CD1 1 
ATOM   898  C  CD2 . TYR A 1 140 ? -0.90822  12.72047  -18.83477 1.000 85.96338  ? 140 TYR A CD2 1 
ATOM   899  C  CE1 . TYR A 1 140 ? 0.25486   13.26481  -16.39060 1.000 84.13167  ? 140 TYR A CE1 1 
ATOM   900  C  CE2 . TYR A 1 140 ? -1.67446  13.24198  -17.80538 1.000 94.17007  ? 140 TYR A CE2 1 
ATOM   901  C  CZ  . TYR A 1 140 ? -1.08810  13.51132  -16.58635 1.000 79.25835  ? 140 TYR A CZ  1 
ATOM   902  O  OH  . TYR A 1 140 ? -1.84772  14.02917  -15.56168 1.000 74.39247  ? 140 TYR A OH  1 
ATOM   903  N  N   . MET A 1 141 ? 1.58226   9.93469   -22.16074 1.000 90.73384  ? 141 MET A N   1 
ATOM   904  C  CA  . MET A 1 141 ? 2.19307   9.56986   -23.42898 1.000 88.98521  ? 141 MET A CA  1 
ATOM   905  C  C   . MET A 1 141 ? 1.70455   10.52234  -24.50771 1.000 86.44283  ? 141 MET A C   1 
ATOM   906  O  O   . MET A 1 141 ? 0.66231   11.16712  -24.37035 1.000 82.91632  ? 141 MET A O   1 
ATOM   907  C  CB  . MET A 1 141 ? 1.86885   8.12481   -23.82503 1.000 84.02210  ? 141 MET A CB  1 
ATOM   908  C  CG  . MET A 1 141 ? 0.38553   7.86392   -24.02257 1.000 92.48416  ? 141 MET A CG  1 
ATOM   909  S  SD  . MET A 1 141 ? 0.04280   6.19194   -24.59550 1.000 82.89939  ? 141 MET A SD  1 
ATOM   910  C  CE  . MET A 1 141 ? 0.87884   6.20647   -26.17806 1.000 82.22255  ? 141 MET A CE  1 
ATOM   911  N  N   . CYS A 1 142 ? 2.47202   10.60160  -25.59161 1.000 96.21244  ? 142 CYS A N   1 
ATOM   912  C  CA  . CYS A 1 142 ? 2.11474   11.47822  -26.69693 1.000 88.74753  ? 142 CYS A CA  1 
ATOM   913  C  C   . CYS A 1 142 ? 2.92844   11.09703  -27.92315 1.000 92.41772  ? 142 CYS A C   1 
ATOM   914  O  O   . CYS A 1 142 ? 4.03529   10.56455  -27.80872 1.000 98.68843  ? 142 CYS A O   1 
ATOM   915  C  CB  . CYS A 1 142 ? 2.35410   12.94615  -26.33366 1.000 85.95091  ? 142 CYS A CB  1 
ATOM   916  S  SG  . CYS A 1 142 ? 4.05355   13.51114  -26.55903 1.000 103.17287 ? 142 CYS A SG  1 
ATOM   917  N  N   . MET A 1 143 ? 2.36781   11.37942  -29.09557 1.000 93.84409  ? 143 MET A N   1 
ATOM   918  C  CA  . MET A 1 143 ? 3.04369   11.16517  -30.36990 1.000 89.43511  ? 143 MET A CA  1 
ATOM   919  C  C   . MET A 1 143 ? 3.56895   12.50525  -30.87184 1.000 89.51661  ? 143 MET A C   1 
ATOM   920  O  O   . MET A 1 143 ? 2.78072   13.41301  -31.15680 1.000 93.93538  ? 143 MET A O   1 
ATOM   921  C  CB  . MET A 1 143 ? 2.09092   10.55081  -31.39527 1.000 87.09124  ? 143 MET A CB  1 
ATOM   922  C  CG  . MET A 1 143 ? 1.39453   9.27686   -30.93966 1.000 81.29859  ? 143 MET A CG  1 
ATOM   923  S  SD  . MET A 1 143 ? 2.48297   7.84260   -30.91067 1.000 91.66092  ? 143 MET A SD  1 
ATOM   924  C  CE  . MET A 1 143 ? 3.02703   7.78833   -32.61497 1.000 85.37184  ? 143 MET A CE  1 
ATOM   925  N  N   . ASP A 1 144 ? 4.88896   12.63001  -30.98420 1.000 91.41157  ? 144 ASP A N   1 
ATOM   926  C  CA  . ASP A 1 144 ? 5.47104   13.89303  -31.41545 1.000 100.33186 ? 144 ASP A CA  1 
ATOM   927  C  C   . ASP A 1 144 ? 5.25254   14.08817  -32.91752 1.000 92.67278  ? 144 ASP A C   1 
ATOM   928  O  O   . ASP A 1 144 ? 4.65950   13.25295  -33.60644 1.000 88.43242  ? 144 ASP A O   1 
ATOM   929  C  CB  . ASP A 1 144 ? 6.95636   13.96144  -31.04157 1.000 92.15868  ? 144 ASP A CB  1 
ATOM   930  C  CG  . ASP A 1 144 ? 7.82355   12.98630  -31.82844 1.000 88.01811  ? 144 ASP A CG  1 
ATOM   931  O  OD1 . ASP A 1 144 ? 7.28885   12.17549  -32.61132 1.000 98.09564  ? 144 ASP A OD1 1 
ATOM   932  O  OD2 . ASP A 1 144 ? 9.06014   13.03546  -31.66061 1.000 82.99842  ? 144 ASP A OD2 1 
ATOM   933  N  N   . GLN A 1 145 ? 5.74639   15.21432  -33.43398 1.000 89.99792  ? 145 GLN A N   1 
ATOM   934  C  CA  . GLN A 1 145 ? 5.53866   15.53851  -34.83928 1.000 100.34063 ? 145 GLN A CA  1 
ATOM   935  C  C   . GLN A 1 145 ? 6.32176   14.63204  -35.78079 1.000 108.42129 ? 145 GLN A C   1 
ATOM   936  O  O   . GLN A 1 145 ? 6.08704   14.68227  -36.99290 1.000 115.28989 ? 145 GLN A O   1 
ATOM   937  C  CB  . GLN A 1 145 ? 5.89132   17.00381  -35.09746 1.000 98.37720  ? 145 GLN A CB  1 
ATOM   938  C  CG  . GLN A 1 145 ? 4.95092   17.98282  -34.40756 1.000 122.85864 ? 145 GLN A CG  1 
ATOM   939  C  CD  . GLN A 1 145 ? 4.97750   19.36290  -35.03507 1.000 127.46443 ? 145 GLN A CD  1 
ATOM   940  O  OE1 . GLN A 1 145 ? 5.99724   19.79273  -35.57411 1.000 130.95642 ? 145 GLN A OE1 1 
ATOM   941  N  NE2 . GLN A 1 145 ? 3.84852   20.06129  -34.97771 1.000 105.98277 ? 145 GLN A NE2 1 
ATOM   942  N  N   . ASP A 1 146 ? 7.23557   13.81261  -35.26218 1.000 105.36639 ? 146 ASP A N   1 
ATOM   943  C  CA  . ASP A 1 146 ? 7.97859   12.85090  -36.06473 1.000 90.82120  ? 146 ASP A CA  1 
ATOM   944  C  C   . ASP A 1 146 ? 7.37248   11.45321  -36.01340 1.000 85.63128  ? 146 ASP A C   1 
ATOM   945  O  O   . ASP A 1 146 ? 7.99518   10.50320  -36.49936 1.000 100.74646 ? 146 ASP A O   1 
ATOM   946  C  CB  . ASP A 1 146 ? 9.44070   12.80412  -35.61500 1.000 86.37911  ? 146 ASP A CB  1 
ATOM   947  C  CG  . ASP A 1 146 ? 10.16678  14.11469  -35.85232 1.000 99.56936  ? 146 ASP A CG  1 
ATOM   948  O  OD1 . ASP A 1 146 ? 10.12944  14.61717  -36.99553 1.000 113.47629 ? 146 ASP A OD1 1 
ATOM   949  O  OD2 . ASP A 1 146 ? 10.76998  14.64458  -34.89488 1.000 101.18925 ? 146 ASP A OD2 1 
ATOM   950  N  N   . ASN A 1 147 ? 6.17792   11.31098  -35.43150 1.000 82.68143  ? 147 ASN A N   1 
ATOM   951  C  CA  . ASN A 1 147 ? 5.46936   10.03538  -35.32509 1.000 87.84413  ? 147 ASN A CA  1 
ATOM   952  C  C   . ASN A 1 147 ? 6.19096   9.04935   -34.40644 1.000 79.84833  ? 147 ASN A C   1 
ATOM   953  O  O   . ASN A 1 147 ? 6.17741   7.84019   -34.64655 1.000 86.19415  ? 147 ASN A O   1 
ATOM   954  C  CB  . ASN A 1 147 ? 5.23177   9.41156   -36.70635 1.000 89.41474  ? 147 ASN A CB  1 
ATOM   955  C  CG  . ASN A 1 147 ? 4.04600   8.47305   -36.72607 1.000 87.20389  ? 147 ASN A CG  1 
ATOM   956  O  OD1 . ASN A 1 147 ? 3.32363   8.34584   -35.73928 1.000 92.10467  ? 147 ASN A OD1 1 
ATOM   957  N  ND2 . ASN A 1 147 ? 3.83098   7.81826   -37.85951 1.000 83.24324  ? 147 ASN A ND2 1 
ATOM   958  N  N   . PHE A 1 148 ? 6.81803   9.55655   -33.34756 1.000 78.31008  ? 148 PHE A N   1 
ATOM   959  C  CA  . PHE A 1 148 ? 7.45989   8.74359   -32.32486 1.000 84.62115  ? 148 PHE A CA  1 
ATOM   960  C  C   . PHE A 1 148 ? 6.78117   8.98116   -30.98140 1.000 88.29250  ? 148 PHE A C   1 
ATOM   961  O  O   . PHE A 1 148 ? 6.31668   10.08722  -30.69108 1.000 88.11563  ? 148 PHE A O   1 
ATOM   962  C  CB  . PHE A 1 148 ? 8.95848   9.06125   -32.20639 1.000 79.57578  ? 148 PHE A CB  1 
ATOM   963  C  CG  . PHE A 1 148 ? 9.79246   8.50235   -33.32419 1.000 79.64188  ? 148 PHE A CG  1 
ATOM   964  C  CD1 . PHE A 1 148 ? 9.96583   9.21147   -34.50043 1.000 79.44479  ? 148 PHE A CD1 1 
ATOM   965  C  CD2 . PHE A 1 148 ? 10.41290  7.27094   -33.19245 1.000 80.56989  ? 148 PHE A CD2 1 
ATOM   966  C  CE1 . PHE A 1 148 ? 10.73607  8.69960   -35.52818 1.000 82.39992  ? 148 PHE A CE1 1 
ATOM   967  C  CE2 . PHE A 1 148 ? 11.18453  6.75371   -34.21607 1.000 79.64873  ? 148 PHE A CE2 1 
ATOM   968  C  CZ  . PHE A 1 148 ? 11.34617  7.46928   -35.38526 1.000 78.99268  ? 148 PHE A CZ  1 
ATOM   969  N  N   . VAL A 1 149 ? 6.73556   7.93431   -30.15823 1.000 81.57892  ? 149 VAL A N   1 
ATOM   970  C  CA  . VAL A 1 149 ? 6.07402   8.00528   -28.85864 1.000 71.94218  ? 149 VAL A CA  1 
ATOM   971  C  C   . VAL A 1 149 ? 7.01529   8.62963   -27.83918 1.000 75.67693  ? 149 VAL A C   1 
ATOM   972  O  O   . VAL A 1 149 ? 8.22606   8.38662   -27.85766 1.000 74.20872  ? 149 VAL A O   1 
ATOM   973  C  CB  . VAL A 1 149 ? 5.62234   6.60657   -28.40301 1.000 71.73840  ? 149 VAL A CB  1 
ATOM   974  C  CG1 . VAL A 1 149 ? 4.63494   6.71375   -27.24932 1.000 66.72978  ? 149 VAL A CG1 1 
ATOM   975  C  CG2 . VAL A 1 149 ? 5.02016   5.84230   -29.55789 1.000 90.48986  ? 149 VAL A CG2 1 
ATOM   976  N  N   . ARG A 1 150 ? 6.45874   9.43262   -26.93543 1.000 93.58177  ? 150 ARG A N   1 
ATOM   977  C  CA  . ARG A 1 150 ? 7.22092   10.04863  -25.86071 1.000 79.75590  ? 150 ARG A CA  1 
ATOM   978  C  C   . ARG A 1 150 ? 6.50458   9.83106   -24.53581 1.000 72.57550  ? 150 ARG A C   1 
ATOM   979  O  O   . ARG A 1 150 ? 5.27252   9.81921   -24.47049 1.000 76.95035  ? 150 ARG A O   1 
ATOM   980  C  CB  . ARG A 1 150 ? 7.43828   11.54628  -26.11345 1.000 74.60286  ? 150 ARG A CB  1 
ATOM   981  C  CG  . ARG A 1 150 ? 8.32620   11.82699  -27.31420 1.000 82.80166  ? 150 ARG A CG  1 
ATOM   982  C  CD  . ARG A 1 150 ? 8.90638   13.22796  -27.27370 1.000 81.02208  ? 150 ARG A CD  1 
ATOM   983  N  NE  . ARG A 1 150 ? 10.05362  13.35499  -28.16565 1.000 76.68695  ? 150 ARG A NE  1 
ATOM   984  C  CZ  . ARG A 1 150 ? 10.82755  14.42826  -28.24331 1.000 86.34998  ? 150 ARG A CZ  1 
ATOM   985  N  NH1 . ARG A 1 150 ? 10.60222  15.49806  -27.49820 1.000 101.54794 ? 150 ARG A NH1 1 
ATOM   986  N  NH2 . ARG A 1 150 ? 11.85458  14.42734  -29.08772 1.000 97.44511  ? 150 ARG A NH2 1 
ATOM   987  N  N   . LEU A 1 151 ? 7.29345   9.65654   -23.47749 1.000 65.71155  ? 151 LEU A N   1 
ATOM   988  C  CA  . LEU A 1 151 ? 6.78194   9.32351   -22.15601 1.000 64.17052  ? 151 LEU A CA  1 
ATOM   989  C  C   . LEU A 1 151 ? 7.31361   10.31841  -21.13620 1.000 69.42282  ? 151 LEU A C   1 
ATOM   990  O  O   . LEU A 1 151 ? 8.46177   10.76167  -21.23196 1.000 78.70442  ? 151 LEU A O   1 
ATOM   991  C  CB  . LEU A 1 151 ? 7.18323   7.89857   -21.75699 1.000 76.15542  ? 151 LEU A CB  1 
ATOM   992  C  CG  . LEU A 1 151 ? 6.78292   6.79475   -22.73746 1.000 61.70040  ? 151 LEU A CG  1 
ATOM   993  C  CD1 . LEU A 1 151 ? 7.45752   5.48147   -22.38032 1.000 49.05744  ? 151 LEU A CD1 1 
ATOM   994  C  CD2 . LEU A 1 151 ? 5.27227   6.63174   -22.76267 1.000 68.46648  ? 151 LEU A CD2 1 
ATOM   995  N  N   . THR A 1 152 ? 6.47871   10.66547  -20.15908 1.000 72.97347  ? 152 THR A N   1 
ATOM   996  C  CA  . THR A 1 152 ? 6.88365   11.61397  -19.13134 1.000 70.57132  ? 152 THR A CA  1 
ATOM   997  C  C   . THR A 1 152 ? 6.05845   11.37476  -17.87606 1.000 72.95887  ? 152 THR A C   1 
ATOM   998  O  O   . THR A 1 152 ? 5.03175   10.69111  -17.90416 1.000 73.07269  ? 152 THR A O   1 
ATOM   999  C  CB  . THR A 1 152 ? 6.72620   13.06351  -19.60625 1.000 67.58518  ? 152 THR A CB  1 
ATOM   1000 O  OG1 . THR A 1 152 ? 7.53702   13.92150  -18.79492 1.000 73.05932  ? 152 THR A OG1 1 
ATOM   1001 C  CG2 . THR A 1 152 ? 5.27460   13.50438  -19.49651 1.000 75.46841  ? 152 THR A CG2 1 
ATOM   1002 N  N   . VAL A 1 153 ? 6.53194   11.94325  -16.76959 1.000 73.75752  ? 153 VAL A N   1 
ATOM   1003 C  CA  . VAL A 1 153 ? 5.85600   11.87226  -15.47998 1.000 70.64290  ? 153 VAL A CA  1 
ATOM   1004 C  C   . VAL A 1 153 ? 5.50400   13.28931  -15.05129 1.000 75.80585  ? 153 VAL A C   1 
ATOM   1005 O  O   . VAL A 1 153 ? 6.37185   14.16969  -15.03247 1.000 74.73376  ? 153 VAL A O   1 
ATOM   1006 C  CB  . VAL A 1 153 ? 6.72799   11.18258  -14.41388 1.000 60.38262  ? 153 VAL A CB  1 
ATOM   1007 C  CG1 . VAL A 1 153 ? 5.92058   10.93790  -13.15073 1.000 63.52285  ? 153 VAL A CG1 1 
ATOM   1008 C  CG2 . VAL A 1 153 ? 7.30303   9.87885   -14.94956 1.000 70.78685  ? 153 VAL A CG2 1 
ATOM   1009 N  N   . SER A 1 154 ? 4.23476   13.51096  -14.71334 1.000 76.71497  ? 154 SER A N   1 
ATOM   1010 C  CA  . SER A 1 154 ? 3.77830   14.81760  -14.24582 1.000 76.49570  ? 154 SER A CA  1 
ATOM   1011 C  C   . SER A 1 154 ? 2.71590   14.60895  -13.17636 1.000 74.95465  ? 154 SER A C   1 
ATOM   1012 O  O   . SER A 1 154 ? 1.58284   14.23110  -13.48999 1.000 79.23315  ? 154 SER A O   1 
ATOM   1013 C  CB  . SER A 1 154 ? 3.23213   15.65990  -15.40003 1.000 90.02047  ? 154 SER A CB  1 
ATOM   1014 O  OG  . SER A 1 154 ? 2.76992   16.92093  -14.94454 1.000 84.14224  ? 154 SER A OG  1 
ATOM   1015 N  N   . GLY A 1 155 ? 3.08238   14.84788  -11.91815 1.000 78.49250  ? 155 GLY A N   1 
ATOM   1016 C  CA  . GLY A 1 155 ? 2.13254   14.80972  -10.82534 1.000 85.44655  ? 155 GLY A CA  1 
ATOM   1017 C  C   . GLY A 1 155 ? 1.41068   16.10907  -10.56148 1.000 97.62110  ? 155 GLY A C   1 
ATOM   1018 O  O   . GLY A 1 155 ? 0.51732   16.15012  -9.71070  1.000 104.85939 ? 155 GLY A O   1 
ATOM   1019 N  N   . THR A 1 156 ? 1.77190   17.17208  -11.27890 1.000 95.52763  ? 156 THR A N   1 
ATOM   1020 C  CA  . THR A 1 156 ? 1.19281   18.50254  -11.09965 1.000 84.65720  ? 156 THR A CA  1 
ATOM   1021 C  C   . THR A 1 156 ? 0.12218   18.79483  -12.14134 1.000 90.25713  ? 156 THR A C   1 
ATOM   1022 O  O   . THR A 1 156 ? -0.02418  19.93224  -12.59993 1.000 103.28335 ? 156 THR A O   1 
ATOM   1023 C  CB  . THR A 1 156 ? 2.28376   19.56969  -11.14234 1.000 90.71533  ? 156 THR A CB  1 
ATOM   1024 O  OG1 . THR A 1 156 ? 2.96061   19.51786  -12.40533 1.000 98.76196  ? 156 THR A OG1 1 
ATOM   1025 C  CG2 . THR A 1 156 ? 3.29002   19.35281  -10.02024 1.000 83.78277  ? 156 THR A CG2 1 
ATOM   1026 N  N   . GLY A 1 157 ? -0.64178  17.77838  -12.52957 1.000 81.20457  ? 157 GLY A N   1 
ATOM   1027 C  CA  . GLY A 1 157 ? -1.63694  17.92298  -13.56170 1.000 86.17362  ? 157 GLY A CA  1 
ATOM   1028 C  C   . GLY A 1 157 ? -1.11722  17.44509  -14.90017 1.000 103.02796 ? 157 GLY A C   1 
ATOM   1029 O  O   . GLY A 1 157 ? -0.06348  16.80557  -14.98859 1.000 95.83388  ? 157 GLY A O   1 
ATOM   1030 N  N   . PRO A 1 158 ? -1.85725  17.73010  -15.96944 1.000 118.30080 ? 158 PRO A N   1 
ATOM   1031 C  CA  . PRO A 1 158 ? -1.40157  17.32735  -17.29478 1.000 106.92257 ? 158 PRO A CA  1 
ATOM   1032 C  C   . PRO A 1 158 ? -0.11536  18.04497  -17.66029 1.000 107.45419 ? 158 PRO A C   1 
ATOM   1033 O  O   . PRO A 1 158 ? 0.12675   19.18287  -17.21897 1.000 111.25113 ? 158 PRO A O   1 
ATOM   1034 C  CB  . PRO A 1 158 ? -2.56214  17.74221  -18.20978 1.000 108.10012 ? 158 PRO A CB  1 
ATOM   1035 C  CG  . PRO A 1 158 ? -3.28983  18.80260  -17.44992 1.000 119.27586 ? 158 PRO A CG  1 
ATOM   1036 C  CD  . PRO A 1 158 ? -3.15757  18.41945  -16.00973 1.000 121.74754 ? 158 PRO A CD  1 
ATOM   1037 N  N   . PRO A 1 159 ? 0.74273   17.41018  -18.45881 1.000 97.49132  ? 159 PRO A N   1 
ATOM   1038 C  CA  . PRO A 1 159 ? 2.02143   18.03947  -18.81411 1.000 89.99276  ? 159 PRO A CA  1 
ATOM   1039 C  C   . PRO A 1 159 ? 1.81526   19.33239  -19.59156 1.000 103.93930 ? 159 PRO A C   1 
ATOM   1040 O  O   . PRO A 1 159 ? 0.84829   19.48893  -20.34100 1.000 95.78888  ? 159 PRO A O   1 
ATOM   1041 C  CB  . PRO A 1 159 ? 2.71600   16.97322  -19.67133 1.000 83.76087  ? 159 PRO A CB  1 
ATOM   1042 C  CG  . PRO A 1 159 ? 2.05921   15.68543  -19.28389 1.000 89.80785  ? 159 PRO A CG  1 
ATOM   1043 C  CD  . PRO A 1 159 ? 0.63206   16.04389  -18.99446 1.000 90.91515  ? 159 PRO A CD  1 
ATOM   1044 N  N   . ALA A 1 160 ? 2.75155   20.26442  -19.40488 1.000 104.93154 ? 160 ALA A N   1 
ATOM   1045 C  CA  . ALA A 1 160 ? 2.64185   21.61876  -19.94448 1.000 100.43278 ? 160 ALA A CA  1 
ATOM   1046 C  C   . ALA A 1 160 ? 3.35858   21.69538  -21.29128 1.000 120.07763 ? 160 ALA A C   1 
ATOM   1047 O  O   . ALA A 1 160 ? 4.47867   22.19382  -21.40896 1.000 122.30619 ? 160 ALA A O   1 
ATOM   1048 C  CB  . ALA A 1 160 ? 3.20115   22.63474  -18.95440 1.000 93.16255  ? 160 ALA A CB  1 
ATOM   1049 N  N   . ASN A 1 161 ? 2.68315   21.20336  -22.32682 1.000 122.20630 ? 161 ASN A N   1 
ATOM   1050 C  CA  . ASN A 1 161 ? 3.16084   21.35950  -23.69376 1.000 114.35964 ? 161 ASN A CA  1 
ATOM   1051 C  C   . ASN A 1 161 ? 1.99492   21.10455  -24.63472 1.000 116.16199 ? 161 ASN A C   1 
ATOM   1052 O  O   . ASN A 1 161 ? 1.02767   20.42415  -24.28339 1.000 106.24926 ? 161 ASN A O   1 
ATOM   1053 C  CB  . ASN A 1 161 ? 4.32655   20.41285  -24.00622 1.000 113.45293 ? 161 ASN A CB  1 
ATOM   1054 C  CG  . ASN A 1 161 ? 5.22409   20.92954  -25.12384 1.000 111.53073 ? 161 ASN A CG  1 
ATOM   1055 O  OD1 . ASN A 1 161 ? 4.80788   21.02087  -26.27839 1.000 115.78633 ? 161 ASN A OD1 1 
ATOM   1056 N  ND2 . ASN A 1 161 ? 6.46699   21.25833  -24.78339 1.000 102.80105 ? 161 ASN A ND2 1 
ATOM   1057 N  N   . SER A 1 162 ? 2.11018   21.64688  -25.84617 1.000 114.41108 ? 162 SER A N   1 
ATOM   1058 C  CA  . SER A 1 162 ? 1.06871   21.48686  -26.85580 1.000 113.53659 ? 162 SER A CA  1 
ATOM   1059 C  C   . SER A 1 162 ? 1.58450   21.11505  -28.23315 1.000 114.81937 ? 162 SER A C   1 
ATOM   1060 O  O   . SER A 1 162 ? 0.76194   20.92152  -29.13588 1.000 123.53634 ? 162 SER A O   1 
ATOM   1061 C  CB  . SER A 1 162 ? 0.27587   22.77886  -26.97152 1.000 118.20624 ? 162 SER A CB  1 
ATOM   1062 O  OG  . SER A 1 162 ? 1.20438   23.82253  -26.83159 1.000 116.79232 ? 162 SER A OG  1 
ATOM   1063 N  N   . GLY A 1 163 ? 2.89882   21.05068  -28.44856 1.000 107.95889 ? 163 GLY A N   1 
ATOM   1064 C  CA  . GLY A 1 163 ? 3.37794   20.28453  -29.57725 1.000 110.55937 ? 163 GLY A CA  1 
ATOM   1065 C  C   . GLY A 1 163 ? 3.06058   18.81614  -29.45554 1.000 116.88503 ? 163 GLY A C   1 
ATOM   1066 O  O   . GLY A 1 163 ? 3.25156   18.06501  -30.41951 1.000 105.44402 ? 163 GLY A O   1 
ATOM   1067 N  N   . CYS A 1 164 ? 2.58916   18.39796  -28.28407 1.000 112.81725 ? 164 CYS A N   1 
ATOM   1068 C  CA  . CYS A 1 164 ? 2.12856   17.04864  -28.02059 1.000 101.81535 ? 164 CYS A CA  1 
ATOM   1069 C  C   . CYS A 1 164 ? 0.81529   17.11864  -27.25503 1.000 106.56927 ? 164 CYS A C   1 
ATOM   1070 O  O   . CYS A 1 164 ? 0.65126   17.96100  -26.36490 1.000 99.46265  ? 164 CYS A O   1 
ATOM   1071 C  CB  . CYS A 1 164 ? 3.16848   16.26623  -27.21733 1.000 99.49680  ? 164 CYS A CB  1 
ATOM   1072 S  SG  . CYS A 1 164 ? 3.86932   14.85005  -28.06812 1.000 138.86918 ? 164 CYS A SG  1 
ATOM   1073 N  N   . GLU A 1 165 ? -0.12005  16.23765  -27.61389 1.000 103.74377 ? 165 GLU A N   1 
ATOM   1074 C  CA  . GLU A 1 165 ? -1.38680  16.08298  -26.89987 1.000 100.15592 ? 165 GLU A CA  1 
ATOM   1075 C  C   . GLU A 1 165 ? -1.21645  14.93151  -25.91330 1.000 99.15714  ? 165 GLU A C   1 
ATOM   1076 O  O   . GLU A 1 165 ? -1.39698  13.76329  -26.26492 1.000 105.00266 ? 165 GLU A O   1 
ATOM   1077 C  CB  . GLU A 1 165 ? -2.53456  15.82647  -27.87101 1.000 100.89064 ? 165 GLU A CB  1 
ATOM   1078 C  CG  . GLU A 1 165 ? -3.88644  15.61800  -27.19897 1.000 115.93675 ? 165 GLU A CG  1 
ATOM   1079 C  CD  . GLU A 1 165 ? -4.97341  15.24112  -28.18744 1.000 123.78661 ? 165 GLU A CD  1 
ATOM   1080 O  OE1 . GLU A 1 165 ? -4.66976  15.15465  -29.39510 1.000 117.93270 ? 165 GLU A OE1 1 
ATOM   1081 O  OE2 . GLU A 1 165 ? -6.12851  15.02840  -27.75879 1.000 128.45467 ? 165 GLU A OE2 1 
ATOM   1082 N  N   . TRP A 1 166 ? -0.87242  15.26222  -24.67583 1.000 92.23747  ? 166 TRP A N   1 
ATOM   1083 C  CA  . TRP A 1 166 ? -0.55163  14.23730  -23.68985 1.000 83.87861  ? 166 TRP A CA  1 
ATOM   1084 C  C   . TRP A 1 166 ? -1.81417  13.54183  -23.19585 1.000 90.56296  ? 166 TRP A C   1 
ATOM   1085 O  O   . TRP A 1 166 ? -2.80116  14.19251  -22.84036 1.000 99.83402  ? 166 TRP A O   1 
ATOM   1086 C  CB  . TRP A 1 166 ? 0.21213   14.85143  -22.51038 1.000 71.46685  ? 166 TRP A CB  1 
ATOM   1087 C  CG  . TRP A 1 166 ? 1.56454   15.38063  -22.88929 1.000 66.53261  ? 166 TRP A CG  1 
ATOM   1088 C  CD1 . TRP A 1 166 ? 1.87126   16.66000  -23.24842 1.000 77.37270  ? 166 TRP A CD1 1 
ATOM   1089 C  CD2 . TRP A 1 166 ? 2.79268   14.64232  -22.94776 1.000 81.81442  ? 166 TRP A CD2 1 
ATOM   1090 N  NE1 . TRP A 1 166 ? 3.21288   16.76609  -23.52528 1.000 78.00423  ? 166 TRP A NE1 1 
ATOM   1091 C  CE2 . TRP A 1 166 ? 3.80120   15.54145  -23.34872 1.000 75.84107  ? 166 TRP A CE2 1 
ATOM   1092 C  CE3 . TRP A 1 166 ? 3.13691   13.30968  -22.70076 1.000 82.56063  ? 166 TRP A CE3 1 
ATOM   1093 C  CZ2 . TRP A 1 166 ? 5.12989   15.15096  -23.50804 1.000 82.42189  ? 166 TRP A CZ2 1 
ATOM   1094 C  CZ3 . TRP A 1 166 ? 4.45679   12.92397  -22.86072 1.000 80.17675  ? 166 TRP A CZ3 1 
ATOM   1095 C  CH2 . TRP A 1 166 ? 5.43664   13.84165  -23.25913 1.000 74.43702  ? 166 TRP A CH2 1 
ATOM   1096 N  N   . LYS A 1 167 ? -1.77391  12.21213  -23.16897 1.000 90.23850  ? 167 LYS A N   1 
ATOM   1097 C  CA  . LYS A 1 167 ? -2.86388  11.38970  -22.66357 1.000 93.30027  ? 167 LYS A CA  1 
ATOM   1098 C  C   . LYS A 1 167 ? -2.30854  10.41752  -21.63373 1.000 90.45291  ? 167 LYS A C   1 
ATOM   1099 O  O   . LYS A 1 167 ? -1.13965  10.03045  -21.69895 1.000 85.69902  ? 167 LYS A O   1 
ATOM   1100 C  CB  . LYS A 1 167 ? -3.55332  10.61143  -23.79137 1.000 91.12294  ? 167 LYS A CB  1 
ATOM   1101 C  CG  . LYS A 1 167 ? -3.92413  11.45212  -25.00239 1.000 98.04547  ? 167 LYS A CG  1 
ATOM   1102 C  CD  . LYS A 1 167 ? -4.42248  10.57881  -26.14265 1.000 93.89442  ? 167 LYS A CD  1 
ATOM   1103 C  CE  . LYS A 1 167 ? -4.72918  11.40538  -27.38095 1.000 101.40833 ? 167 LYS A CE  1 
ATOM   1104 N  NZ  . LYS A 1 167 ? -5.19217  10.56157  -28.51794 1.000 88.60820  ? 167 LYS A NZ  1 
ATOM   1105 N  N   . LEU A 1 168 ? -3.15114  10.01367  -20.68693 1.000 79.70477  ? 168 LEU A N   1 
ATOM   1106 C  CA  . LEU A 1 168 ? -2.71571  9.08369   -19.65176 1.000 87.04361  ? 168 LEU A CA  1 
ATOM   1107 C  C   . LEU A 1 168 ? -2.56146  7.68190   -20.23007 1.000 92.18122  ? 168 LEU A C   1 
ATOM   1108 O  O   . LEU A 1 168 ? -3.48709  7.15293   -20.85458 1.000 95.38171  ? 168 LEU A O   1 
ATOM   1109 C  CB  . LEU A 1 168 ? -3.70766  9.06591   -18.48757 1.000 86.49951  ? 168 LEU A CB  1 
ATOM   1110 C  CG  . LEU A 1 168 ? -3.42746  10.05234  -17.35805 1.000 82.88646  ? 168 LEU A CG  1 
ATOM   1111 C  CD1 . LEU A 1 168 ? -4.47599  9.92358   -16.26676 1.000 60.12980  ? 168 LEU A CD1 1 
ATOM   1112 C  CD2 . LEU A 1 168 ? -2.03256  9.83334   -16.78952 1.000 87.11466  ? 168 LEU A CD2 1 
ATOM   1113 N  N   . VAL A 1 169 ? -1.38456  7.08403   -20.01646 1.000 94.19170  ? 169 VAL A N   1 
ATOM   1114 C  CA  . VAL A 1 169 ? -1.12995  5.72357   -20.48404 1.000 94.70027  ? 169 VAL A CA  1 
ATOM   1115 C  C   . VAL A 1 169 ? -2.11648  4.74808   -19.86015 1.000 93.78851  ? 169 VAL A C   1 
ATOM   1116 O  O   . VAL A 1 169 ? -2.51148  3.75988   -20.49070 1.000 94.14119  ? 169 VAL A O   1 
ATOM   1117 C  CB  . VAL A 1 169 ? 0.32840   5.31708   -20.18187 1.000 81.92681  ? 169 VAL A CB  1 
ATOM   1118 C  CG1 . VAL A 1 169 ? 0.61094   3.91185   -20.68820 1.000 61.99210  ? 169 VAL A CG1 1 
ATOM   1119 C  CG2 . VAL A 1 169 ? 1.29875   6.30834   -20.79901 1.000 87.31516  ? 169 VAL A CG2 1 
ATOM   1120 N  N   . GLU A 1 170 ? -2.53266  5.00855   -18.61950 1.000 80.04412  ? 170 GLU A N   1 
ATOM   1121 C  CA  . GLU A 1 170 ? -3.47980  4.12953   -17.94105 1.000 80.79244  ? 170 GLU A CA  1 
ATOM   1122 C  C   . GLU A 1 170 ? -4.79458  4.02798   -18.70707 1.000 94.68864  ? 170 GLU A C   1 
ATOM   1123 O  O   . GLU A 1 170 ? -5.28004  2.92558   -18.98608 1.000 102.24661 ? 170 GLU A O   1 
ATOM   1124 C  CB  . GLU A 1 170 ? -3.71928  4.63843   -16.52048 1.000 95.77906  ? 170 GLU A CB  1 
ATOM   1125 C  CG  . GLU A 1 170 ? -4.76741  3.86883   -15.73940 1.000 100.55963 ? 170 GLU A CG  1 
ATOM   1126 C  CD  . GLU A 1 170 ? -4.86977  4.33775   -14.30172 1.000 99.38615  ? 170 GLU A CD  1 
ATOM   1127 O  OE1 . GLU A 1 170 ? -4.03689  5.17307   -13.88893 1.000 95.10929  ? 170 GLU A OE1 1 
ATOM   1128 O  OE2 . GLU A 1 170 ? -5.78257  3.87371   -13.58664 1.000 108.22122 ? 170 GLU A OE2 1 
ATOM   1129 N  N   . THR A 1 171 ? -5.38828  5.17195   -19.05555 1.000 93.73703  ? 171 THR A N   1 
ATOM   1130 C  CA  . THR A 1 171 ? -6.67101  5.15671   -19.75315 1.000 85.82288  ? 171 THR A CA  1 
ATOM   1131 C  C   . THR A 1 171 ? -6.51504  4.66801   -21.18758 1.000 92.07646  ? 171 THR A C   1 
ATOM   1132 O  O   . THR A 1 171 ? -7.30498  3.84317   -21.66209 1.000 106.04320 ? 171 THR A O   1 
ATOM   1133 C  CB  . THR A 1 171 ? -7.30254  6.54883   -19.72961 1.000 88.16797  ? 171 THR A CB  1 
ATOM   1134 O  OG1 . THR A 1 171 ? -7.51273  6.95802   -18.37280 1.000 102.71046 ? 171 THR A OG1 1 
ATOM   1135 C  CG2 . THR A 1 171 ? -8.63656  6.54185   -20.46595 1.000 86.27043  ? 171 THR A CG2 1 
ATOM   1136 N  N   . GLU A 1 172 ? -5.49657  5.16641   -21.89400 1.000 87.10174  ? 172 GLU A N   1 
ATOM   1137 C  CA  . GLU A 1 172 ? -5.29901  4.77720   -23.28626 1.000 91.46832  ? 172 GLU A CA  1 
ATOM   1138 C  C   . GLU A 1 172 ? -5.03856  3.28355   -23.42417 1.000 92.75327  ? 172 GLU A C   1 
ATOM   1139 O  O   . GLU A 1 172 ? -5.35298  2.69613   -24.46412 1.000 92.71612  ? 172 GLU A O   1 
ATOM   1140 C  CB  . GLU A 1 172 ? -4.14689  5.57603   -23.89674 1.000 93.60233  ? 172 GLU A CB  1 
ATOM   1141 C  CG  . GLU A 1 172 ? -4.44681  7.05483   -24.08386 1.000 102.23756 ? 172 GLU A CG  1 
ATOM   1142 C  CD  . GLU A 1 172 ? -5.51696  7.30737   -25.12808 1.000 108.68071 ? 172 GLU A CD  1 
ATOM   1143 O  OE1 . GLU A 1 172 ? -5.40117  6.75985   -26.24519 1.000 106.94802 ? 172 GLU A OE1 1 
ATOM   1144 O  OE2 . GLU A 1 172 ? -6.47612  8.05005   -24.82896 1.000 112.46506 ? 172 GLU A OE2 1 
ATOM   1145 N  N   . ARG A 1 173 ? -4.46754  2.65545   -22.39347 1.000 90.10867  ? 173 ARG A N   1 
ATOM   1146 C  CA  . ARG A 1 173 ? -4.22944  1.21608   -22.43972 1.000 83.85832  ? 173 ARG A CA  1 
ATOM   1147 C  C   . ARG A 1 173 ? -5.52882  0.43058   -22.30755 1.000 92.35233  ? 173 ARG A C   1 
ATOM   1148 O  O   . ARG A 1 173 ? -5.75829  -0.52947  -23.05245 1.000 92.77229  ? 173 ARG A O   1 
ATOM   1149 C  CB  . ARG A 1 173 ? -3.24577  0.81755   -21.33824 1.000 82.74422  ? 173 ARG A CB  1 
ATOM   1150 C  CG  . ARG A 1 173 ? -3.17189  -0.67341  -21.06605 1.000 94.10077  ? 173 ARG A CG  1 
ATOM   1151 C  CD  . ARG A 1 173 ? -2.18963  -0.98892  -19.94502 1.000 84.74657  ? 173 ARG A CD  1 
ATOM   1152 N  NE  . ARG A 1 173 ? -0.80679  -0.73592  -20.33398 1.000 81.92013  ? 173 ARG A NE  1 
ATOM   1153 C  CZ  . ARG A 1 173 ? -0.00289  0.13254   -19.73545 1.000 77.20726  ? 173 ARG A CZ  1 
ATOM   1154 N  NH1 . ARG A 1 173 ? -0.40305  0.84023   -18.69160 1.000 63.86090  ? 173 ARG A NH1 1 
ATOM   1155 N  NH2 . ARG A 1 173 ? 1.23758   0.28683   -20.18929 1.000 76.48785  ? 173 ARG A NH2 1 
ATOM   1156 N  N   . ALA A 1 174 ? -6.39051  0.82139   -21.36527 1.000 85.08831  ? 174 ALA A N   1 
ATOM   1157 C  CA  . ALA A 1 174 ? -7.64012  0.09584   -21.15638 1.000 94.12603  ? 174 ALA A CA  1 
ATOM   1158 C  C   . ALA A 1 174 ? -8.57684  0.24247   -22.34795 1.000 99.30622  ? 174 ALA A C   1 
ATOM   1159 O  O   . ALA A 1 174 ? -9.26222  -0.71415  -22.72876 1.000 108.17871 ? 174 ALA A O   1 
ATOM   1160 C  CB  . ALA A 1 174 ? -8.32169  0.57503   -19.87595 1.000 86.83003  ? 174 ALA A CB  1 
ATOM   1161 N  N   . ASN A 1 175 ? -8.61712  1.42571   -22.95210 1.000 88.62105  ? 175 ASN A N   1 
ATOM   1162 C  CA  . ASN A 1 175 ? -9.52692  1.71210   -24.05432 1.000 90.92973  ? 175 ASN A CA  1 
ATOM   1163 C  C   . ASN A 1 175 ? -9.02117  1.18483   -25.39602 1.000 97.56691  ? 175 ASN A C   1 
ATOM   1164 O  O   . ASN A 1 175 ? -9.49279  1.64329   -26.44292 1.000 99.57555  ? 175 ASN A O   1 
ATOM   1165 C  CB  . ASN A 1 175 ? -9.78343  3.22021   -24.13777 1.000 88.96310  ? 175 ASN A CB  1 
ATOM   1166 C  CG  . ASN A 1 175 ? -10.48230 3.76285   -22.90324 1.000 94.38993  ? 175 ASN A CG  1 
ATOM   1167 O  OD1 . ASN A 1 175 ? -10.76876 3.02087   -21.96354 1.000 102.74462 ? 175 ASN A OD1 1 
ATOM   1168 N  ND2 . ASN A 1 175 ? -10.75675 5.06304   -22.89788 1.000 87.91005  ? 175 ASN A ND2 1 
ATOM   1169 N  N   . SER A 1 176 ? -8.06992  0.24782   -25.38876 1.000 95.49052  ? 176 SER A N   1 
ATOM   1170 C  CA  . SER A 1 176 ? -7.54401  -0.32516  -26.62472 1.000 98.10483  ? 176 SER A CA  1 
ATOM   1171 C  C   . SER A 1 176 ? -8.27106  -1.61158  -27.01253 1.000 96.78234  ? 176 SER A C   1 
ATOM   1172 O  O   . SER A 1 176 ? -8.89904  -1.68152  -28.07254 1.000 104.67661 ? 176 SER A O   1 
ATOM   1173 C  CB  . SER A 1 176 ? -6.04135  -0.59819  -26.49176 1.000 95.85557  ? 176 SER A CB  1 
ATOM   1174 O  OG  . SER A 1 176 ? -5.35728  0.47697   -25.87653 1.000 113.47393 ? 176 SER A OG  1 
ATOM   1175 N  N   . GLY A 1 177 ? -8.20361  -2.62979  -26.16141 1.000 98.69804  ? 177 GLY A N   1 
ATOM   1176 C  CA  . GLY A 1 177 ? -8.79962  -3.91320  -26.47242 1.000 100.50221 ? 177 GLY A CA  1 
ATOM   1177 C  C   . GLY A 1 177 ? -7.87603  -5.09005  -26.23291 1.000 105.79907 ? 177 GLY A C   1 
ATOM   1178 O  O   . GLY A 1 177 ? -8.30700  -6.12938  -25.72419 1.000 111.20093 ? 177 GLY A O   1 
ATOM   1179 N  N   . ASP A 1 178 ? -6.59945  -4.93908  -26.57941 1.000 96.73541  ? 178 ASP A N   1 
ATOM   1180 C  CA  . ASP A 1 178 ? -5.58420  -5.94924  -26.29554 1.000 89.05244  ? 178 ASP A CA  1 
ATOM   1181 C  C   . ASP A 1 178 ? -4.41447  -5.23867  -25.63448 1.000 92.28781  ? 178 ASP A C   1 
ATOM   1182 O  O   . ASP A 1 178 ? -3.64233  -4.54855  -26.30569 1.000 94.04504  ? 178 ASP A O   1 
ATOM   1183 C  CB  . ASP A 1 178 ? -5.14322  -6.68420  -27.56052 1.000 92.21837  ? 178 ASP A CB  1 
ATOM   1184 C  CG  . ASP A 1 178 ? -4.31493  -7.91994  -27.25919 1.000 103.62936 ? 178 ASP A CG  1 
ATOM   1185 O  OD1 . ASP A 1 178 ? -3.23952  -7.78444  -26.63622 1.000 114.29593 ? 178 ASP A OD1 1 
ATOM   1186 O  OD2 . ASP A 1 178 ? -4.75512  -9.02948  -27.63033 1.000 109.16448 ? 178 ASP A OD2 1 
ATOM   1187 N  N   . ILE A 1 179 ? -4.29170  -5.41263  -24.31689 1.000 92.69312  ? 179 ILE A N   1 
ATOM   1188 C  CA  . ILE A 1 179 ? -3.27579  -4.70107  -23.55252 1.000 90.78292  ? 179 ILE A CA  1 
ATOM   1189 C  C   . ILE A 1 179 ? -1.87473  -5.13635  -23.96632 1.000 84.70789  ? 179 ILE A C   1 
ATOM   1190 O  O   . ILE A 1 179 ? -0.94686  -4.31825  -23.99535 1.000 95.94445  ? 179 ILE A O   1 
ATOM   1191 C  CB  . ILE A 1 179 ? -3.53090  -4.90737  -22.04793 1.000 86.03225  ? 179 ILE A CB  1 
ATOM   1192 C  CG1 . ILE A 1 179 ? -4.90018  -4.33423  -21.66213 1.000 78.88828  ? 179 ILE A CG1 1 
ATOM   1193 C  CG2 . ILE A 1 179 ? -2.42083  -4.28945  -21.22781 1.000 90.47121  ? 179 ILE A CG2 1 
ATOM   1194 C  CD1 . ILE A 1 179 ? -5.18529  -4.36021  -20.17168 1.000 77.23255  ? 179 ILE A CD1 1 
ATOM   1195 N  N   . ALA A 1 180 ? -1.69391  -6.41423  -24.30819 1.000 74.43265  ? 180 ALA A N   1 
ATOM   1196 C  CA  . ALA A 1 180 ? -0.38068  -6.87430  -24.74887 1.000 78.90303  ? 180 ALA A CA  1 
ATOM   1197 C  C   . ALA A 1 180 ? 0.03155   -6.19624  -26.04830 1.000 82.02338  ? 180 ALA A C   1 
ATOM   1198 O  O   . ALA A 1 180 ? 1.21350   -5.89818  -26.25272 1.000 83.95752  ? 180 ALA A O   1 
ATOM   1199 C  CB  . ALA A 1 180 ? -0.37701  -8.39392  -24.91216 1.000 75.85903  ? 180 ALA A CB  1 
ATOM   1200 N  N   . ALA A 1 181 ? -0.92723  -5.96314  -26.94779 1.000 80.35696  ? 181 ALA A N   1 
ATOM   1201 C  CA  . ALA A 1 181 ? -0.62593  -5.24811  -28.18315 1.000 75.66613  ? 181 ALA A CA  1 
ATOM   1202 C  C   . ALA A 1 181 ? -0.18231  -3.82071  -27.89568 1.000 79.41592  ? 181 ALA A C   1 
ATOM   1203 O  O   . ALA A 1 181 ? 0.74656   -3.30960  -28.53195 1.000 81.08838  ? 181 ALA A O   1 
ATOM   1204 C  CB  . ALA A 1 181 ? -1.84317  -5.25903  -29.10582 1.000 75.74640  ? 181 ALA A CB  1 
ATOM   1205 N  N   . PHE A 1 182 ? -0.84468  -3.15968  -26.94379 1.000 83.75312  ? 182 PHE A N   1 
ATOM   1206 C  CA  . PHE A 1 182 ? -0.43952  -1.81730  -26.54054 1.000 77.10865  ? 182 PHE A CA  1 
ATOM   1207 C  C   . PHE A 1 182 ? 0.97674   -1.81868  -25.97857 1.000 80.99246  ? 182 PHE A C   1 
ATOM   1208 O  O   . PHE A 1 182 ? 1.76276   -0.90228  -26.24912 1.000 87.60695  ? 182 PHE A O   1 
ATOM   1209 C  CB  . PHE A 1 182 ? -1.43583  -1.27013  -25.51593 1.000 72.11145  ? 182 PHE A CB  1 
ATOM   1210 C  CG  . PHE A 1 182 ? -1.16731  0.14614   -25.09038 1.000 84.61861  ? 182 PHE A CG  1 
ATOM   1211 C  CD1 . PHE A 1 182 ? -1.67653  1.20941   -25.81795 1.000 90.19689  ? 182 PHE A CD1 1 
ATOM   1212 C  CD2 . PHE A 1 182 ? -0.42718  0.41325   -23.94961 1.000 77.40245  ? 182 PHE A CD2 1 
ATOM   1213 C  CE1 . PHE A 1 182 ? -1.44012  2.51357   -25.42521 1.000 86.10901  ? 182 PHE A CE1 1 
ATOM   1214 C  CE2 . PHE A 1 182 ? -0.18689  1.71438   -23.55174 1.000 83.78901  ? 182 PHE A CE2 1 
ATOM   1215 C  CZ  . PHE A 1 182 ? -0.69460  2.76586   -24.29044 1.000 92.79292  ? 182 PHE A CZ  1 
ATOM   1216 N  N   . ASP A 1 183 ? 1.31986   -2.84140  -25.19431 1.000 79.74925  ? 183 ASP A N   1 
ATOM   1217 C  CA  . ASP A 1 183 ? 2.64008   -2.93838  -24.58495 1.000 81.23980  ? 183 ASP A CA  1 
ATOM   1218 C  C   . ASP A 1 183 ? 3.70376   -3.47380  -25.53464 1.000 78.96662  ? 183 ASP A C   1 
ATOM   1219 O  O   . ASP A 1 183 ? 4.89478   -3.36347  -25.22667 1.000 83.19074  ? 183 ASP A O   1 
ATOM   1220 C  CB  . ASP A 1 183 ? 2.57656   -3.82617  -23.34048 1.000 76.51498  ? 183 ASP A CB  1 
ATOM   1221 C  CG  . ASP A 1 183 ? 1.73489   -3.22232  -22.24102 1.000 79.83763  ? 183 ASP A CG  1 
ATOM   1222 O  OD1 . ASP A 1 183 ? 1.39440   -2.02487  -22.34125 1.000 78.53072  ? 183 ASP A OD1 1 
ATOM   1223 O  OD2 . ASP A 1 183 ? 1.42545   -3.94707  -21.27338 1.000 76.47131  ? 183 ASP A OD2 1 
ATOM   1224 N  N   . HIS A 1 184 ? 3.31565   -4.05524  -26.66839 1.000 76.39939  ? 184 HIS A N   1 
ATOM   1225 C  CA  . HIS A 1 184 ? 4.29128   -4.43527  -27.68179 1.000 77.50111  ? 184 HIS A CA  1 
ATOM   1226 C  C   . HIS A 1 184 ? 4.55264   -3.30571  -28.66318 1.000 83.12435  ? 184 HIS A C   1 
ATOM   1227 O  O   . HIS A 1 184 ? 5.67804   -3.16222  -29.15444 1.000 80.90982  ? 184 HIS A O   1 
ATOM   1228 C  CB  . HIS A 1 184 ? 3.81891   -5.67725  -28.44184 1.000 87.69288  ? 184 HIS A CB  1 
ATOM   1229 C  CG  . HIS A 1 184 ? 4.84459   -6.23798  -29.37791 1.000 92.15525  ? 184 HIS A CG  1 
ATOM   1230 N  ND1 . HIS A 1 184 ? 5.78930   -7.15988  -28.98045 1.000 102.09380 ? 184 HIS A ND1 1 
ATOM   1231 C  CD2 . HIS A 1 184 ? 5.07832   -6.00272  -30.69078 1.000 86.83237  ? 184 HIS A CD2 1 
ATOM   1232 C  CE1 . HIS A 1 184 ? 6.55815   -7.47127  -30.00873 1.000 94.93425  ? 184 HIS A CE1 1 
ATOM   1233 N  NE2 . HIS A 1 184 ? 6.14830   -6.78246  -31.05869 1.000 93.35548  ? 184 HIS A NE2 1 
ATOM   1234 N  N   . TRP A 1 185 ? 3.52669   -2.50482  -28.95371 1.000 84.45164  ? 185 TRP A N   1 
ATOM   1235 C  CA  . TRP A 1 185 ? 3.70699   -1.30827  -29.76721 1.000 80.03962  ? 185 TRP A CA  1 
ATOM   1236 C  C   . TRP A 1 185 ? 4.61065   -0.30263  -29.06438 1.000 73.10398  ? 185 TRP A C   1 
ATOM   1237 O  O   . TRP A 1 185 ? 5.40732   0.38594   -29.71269 1.000 83.49685  ? 185 TRP A O   1 
ATOM   1238 C  CB  . TRP A 1 185 ? 2.33765   -0.70453  -30.08198 1.000 75.28946  ? 185 TRP A CB  1 
ATOM   1239 C  CG  . TRP A 1 185 ? 2.35547   0.64514   -30.72652 1.000 80.50480  ? 185 TRP A CG  1 
ATOM   1240 C  CD1 . TRP A 1 185 ? 2.56358   0.92240   -32.04481 1.000 89.75121  ? 185 TRP A CD1 1 
ATOM   1241 C  CD2 . TRP A 1 185 ? 2.11249   1.90273   -30.08551 1.000 82.52572  ? 185 TRP A CD2 1 
ATOM   1242 N  NE1 . TRP A 1 185 ? 2.48318   2.27746   -32.26210 1.000 95.91791  ? 185 TRP A NE1 1 
ATOM   1243 C  CE2 . TRP A 1 185 ? 2.20843   2.90147   -31.07386 1.000 92.36983  ? 185 TRP A CE2 1 
ATOM   1244 C  CE3 . TRP A 1 185 ? 1.83216   2.28106   -28.77028 1.000 78.39529  ? 185 TRP A CE3 1 
ATOM   1245 C  CZ2 . TRP A 1 185 ? 2.03452   4.25403   -30.78778 1.000 90.21661  ? 185 TRP A CZ2 1 
ATOM   1246 C  CZ3 . TRP A 1 185 ? 1.66116   3.62339   -28.48781 1.000 86.91193  ? 185 TRP A CZ3 1 
ATOM   1247 C  CH2 . TRP A 1 185 ? 1.76129   4.59359   -29.49176 1.000 84.26972  ? 185 TRP A CH2 1 
ATOM   1248 N  N   . LEU A 1 186 ? 4.49896   -0.20740  -27.73587 1.000 69.69297  ? 186 LEU A N   1 
ATOM   1249 C  CA  . LEU A 1 186 ? 5.36678   0.68159   -26.96999 1.000 70.81582  ? 186 LEU A CA  1 
ATOM   1250 C  C   . LEU A 1 186 ? 6.83269   0.29891   -27.13760 1.000 67.77538  ? 186 LEU A C   1 
ATOM   1251 O  O   . LEU A 1 186 ? 7.69235   1.15975   -27.35166 1.000 77.56854  ? 186 LEU A O   1 
ATOM   1252 C  CB  . LEU A 1 186 ? 4.97545   0.64578   -25.49074 1.000 74.39186  ? 186 LEU A CB  1 
ATOM   1253 C  CG  . LEU A 1 186 ? 4.28540   1.85291   -24.84482 1.000 57.72703  ? 186 LEU A CG  1 
ATOM   1254 C  CD1 . LEU A 1 186 ? 2.98304   2.18135   -25.53956 1.000 65.33707  ? 186 LEU A CD1 1 
ATOM   1255 C  CD2 . LEU A 1 186 ? 4.04278   1.59016   -23.36491 1.000 70.65181  ? 186 LEU A CD2 1 
ATOM   1256 N  N   . LYS A 1 187 ? 7.13640   -0.99666  -27.03945 1.000 67.11829  ? 187 LYS A N   1 
ATOM   1257 C  CA  . LYS A 1 187 ? 8.52147   -1.44325  -27.14599 1.000 61.24508  ? 187 LYS A CA  1 
ATOM   1258 C  C   . LYS A 1 187 ? 9.03814   -1.31276  -28.57221 1.000 75.29386  ? 187 LYS A C   1 
ATOM   1259 O  O   . LYS A 1 187 ? 10.18400  -0.89539  -28.78806 1.000 78.91279  ? 187 LYS A O   1 
ATOM   1260 C  CB  . LYS A 1 187 ? 8.64831   -2.88521  -26.65965 1.000 61.41311  ? 187 LYS A CB  1 
ATOM   1261 C  CG  . LYS A 1 187 ? 10.04191  -3.46433  -26.80908 1.000 57.96294  ? 187 LYS A CG  1 
ATOM   1262 C  CD  . LYS A 1 187 ? 10.04613  -4.95382  -26.52261 1.000 62.13410  ? 187 LYS A CD  1 
ATOM   1263 C  CE  . LYS A 1 187 ? 11.43584  -5.54227  -26.69478 1.000 74.08476  ? 187 LYS A CE  1 
ATOM   1264 N  NZ  . LYS A 1 187 ? 11.44978  -7.00926  -26.43610 1.000 86.06229  ? 187 LYS A NZ  1 
ATOM   1265 N  N   . SER A 1 188 ? 8.21220   -1.66998  -29.55924 1.000 75.81816  ? 188 SER A N   1 
ATOM   1266 C  CA  . SER A 1 188 ? 8.62057   -1.52796  -30.95184 1.000 71.26903  ? 188 SER A CA  1 
ATOM   1267 C  C   . SER A 1 188 ? 8.90182   -0.07392  -31.30362 1.000 76.10897  ? 188 SER A C   1 
ATOM   1268 O  O   . SER A 1 188 ? 9.70028   0.20649   -32.20369 1.000 78.27382  ? 188 SER A O   1 
ATOM   1269 C  CB  . SER A 1 188 ? 7.54104   -2.09436  -31.87624 1.000 77.68769  ? 188 SER A CB  1 
ATOM   1270 O  OG  . SER A 1 188 ? 7.22040   -3.43016  -31.53693 1.000 103.57918 ? 188 SER A OG  1 
ATOM   1271 N  N   . ASN A 1 189 ? 8.26167   0.86089   -30.60338 1.000 69.76907  ? 189 ASN A N   1 
ATOM   1272 C  CA  . ASN A 1 189 ? 8.37650   2.26994   -30.95450 1.000 69.83200  ? 189 ASN A CA  1 
ATOM   1273 C  C   . ASN A 1 189 ? 9.63119   2.91577   -30.39086 1.000 70.26856  ? 189 ASN A C   1 
ATOM   1274 O  O   . ASN A 1 189 ? 10.12790  3.89219   -30.96494 1.000 73.51867  ? 189 ASN A O   1 
ATOM   1275 C  CB  . ASN A 1 189 ? 7.14459   3.02359   -30.46282 1.000 68.06233  ? 189 ASN A CB  1 
ATOM   1276 C  CG  . ASN A 1 189 ? 6.18621   3.32740   -31.56992 1.000 73.40109  ? 189 ASN A CG  1 
ATOM   1277 O  OD1 . ASN A 1 189 ? 6.18837   4.43024   -32.10894 1.000 68.37550  ? 189 ASN A OD1 1 
ATOM   1278 N  ND2 . ASN A 1 189 ? 5.36726   2.35041   -31.93272 1.000 87.97842  ? 189 ASN A ND2 1 
ATOM   1279 N  N   . ILE A 1 190 ? 10.15476  2.39910   -29.28316 1.000 70.58100  ? 190 ILE A N   1 
ATOM   1280 C  CA  . ILE A 1 190 ? 11.28609  3.01564   -28.61174 1.000 75.05591  ? 190 ILE A CA  1 
ATOM   1281 C  C   . ILE A 1 190 ? 12.53659  2.15112   -28.70230 1.000 69.75844  ? 190 ILE A C   1 
ATOM   1282 O  O   . ILE A 1 190 ? 13.54371  2.45476   -28.05567 1.000 80.95797  ? 190 ILE A O   1 
ATOM   1283 C  CB  . ILE A 1 190 ? 10.94120  3.35092   -27.15124 1.000 65.17520  ? 190 ILE A CB  1 
ATOM   1284 C  CG1 . ILE A 1 190 ? 10.68979  2.08006   -26.34322 1.000 72.85171  ? 190 ILE A CG1 1 
ATOM   1285 C  CG2 . ILE A 1 190 ? 9.72152   4.27399   -27.08765 1.000 62.58569  ? 190 ILE A CG2 1 
ATOM   1286 C  CD1 . ILE A 1 190 ? 10.11997  2.33988   -24.95836 1.000 69.35168  ? 190 ILE A CD1 1 
ATOM   1287 N  N   . SER A 1 191 ? 12.50424  1.08367   -29.49437 1.000 63.19185  ? 191 SER A N   1 
ATOM   1288 C  CA  . SER A 1 191 ? 13.67790  0.25259   -29.72002 1.000 67.39798  ? 191 SER A CA  1 
ATOM   1289 C  C   . SER A 1 191 ? 14.27827  0.54873   -31.08885 1.000 70.35875  ? 191 SER A C   1 
ATOM   1290 O  O   . SER A 1 191 ? 13.58822  0.99638   -32.00827 1.000 71.13430  ? 191 SER A O   1 
ATOM   1291 C  CB  . SER A 1 191 ? 13.32706  -1.22807  -29.61600 1.000 65.72458  ? 191 SER A CB  1 
ATOM   1292 O  OG  . SER A 1 191 ? 14.44792  -2.03651  -29.93817 1.000 59.44434  ? 191 SER A OG  1 
ATOM   1293 N  N   . LEU A 1 192 ? 15.57922  0.30454   -31.21055 1.000 65.74252  ? 192 LEU A N   1 
ATOM   1294 C  CA  . LEU A 1 192 ? 16.27353  0.48228   -32.47613 1.000 53.21233  ? 192 LEU A CA  1 
ATOM   1295 C  C   . LEU A 1 192 ? 16.35511  -0.79908  -33.28797 1.000 58.94039  ? 192 LEU A C   1 
ATOM   1296 O  O   . LEU A 1 192 ? 16.67691  -0.73638  -34.47884 1.000 69.25716  ? 192 LEU A O   1 
ATOM   1297 C  CB  . LEU A 1 192 ? 17.68981  1.02258   -32.24262 1.000 46.81902  ? 192 LEU A CB  1 
ATOM   1298 C  CG  . LEU A 1 192 ? 17.86825  2.53717   -32.10560 1.000 58.76250  ? 192 LEU A CG  1 
ATOM   1299 C  CD1 . LEU A 1 192 ? 17.19844  3.07195   -30.84487 1.000 73.54655  ? 192 LEU A CD1 1 
ATOM   1300 C  CD2 . LEU A 1 192 ? 19.34637  2.90563   -32.13276 1.000 58.01685  ? 192 LEU A CD2 1 
ATOM   1301 N  N   . LEU A 1 193 ? 16.07114  -1.95237  -32.68229 1.000 63.38838  ? 193 LEU A N   1 
ATOM   1302 C  CA  . LEU A 1 193 ? 16.13403  -3.22905  -33.37879 1.000 68.26304  ? 193 LEU A CA  1 
ATOM   1303 C  C   . LEU A 1 193 ? 14.75309  -3.74295  -33.77285 1.000 60.93774  ? 193 LEU A C   1 
ATOM   1304 O  O   . LEU A 1 193 ? 14.60501  -4.92772  -34.09273 1.000 69.96523  ? 193 LEU A O   1 
ATOM   1305 C  CB  . LEU A 1 193 ? 16.87112  -4.26700  -32.52943 1.000 65.80276  ? 193 LEU A CB  1 
ATOM   1306 C  CG  . LEU A 1 193 ? 17.73752  -5.25057  -33.32479 1.000 64.34074  ? 193 LEU A CG  1 
ATOM   1307 C  CD1 . LEU A 1 193 ? 18.90117  -4.52566  -33.98347 1.000 75.00952  ? 193 LEU A CD1 1 
ATOM   1308 C  CD2 . LEU A 1 193 ? 18.24010  -6.38690  -32.44858 1.000 70.64017  ? 193 LEU A CD2 1 
ATOM   1309 N  N   . THR A 1 194 ? 13.73715  -2.87654  -33.74639 1.000 65.36881  ? 194 THR A N   1 
ATOM   1310 C  CA  . THR A 1 194 ? 12.44675  -3.23167  -34.32306 1.000 65.30984  ? 194 THR A CA  1 
ATOM   1311 C  C   . THR A 1 194 ? 12.52479  -3.33432  -35.83914 1.000 70.00495  ? 194 THR A C   1 
ATOM   1312 O  O   . THR A 1 194 ? 11.71133  -4.03731  -36.44895 1.000 68.84992  ? 194 THR A O   1 
ATOM   1313 C  CB  . THR A 1 194 ? 11.38421  -2.20765  -33.92043 1.000 66.55247  ? 194 THR A CB  1 
ATOM   1314 O  OG1 . THR A 1 194 ? 10.13321  -2.54222  -34.53425 1.000 75.21802  ? 194 THR A OG1 1 
ATOM   1315 C  CG2 . THR A 1 194 ? 11.80120  -0.80988  -34.35562 1.000 79.27761  ? 194 THR A CG2 1 
ATOM   1316 N  N   . THR A 1 195 ? 13.48359  -2.64310  -36.45131 1.000 72.06681  ? 195 THR A N   1 
ATOM   1317 C  CA  . THR A 1 195 ? 13.78988  -2.75841  -37.86727 1.000 59.37448  ? 195 THR A CA  1 
ATOM   1318 C  C   . THR A 1 195 ? 15.30196  -2.82424  -38.00803 1.000 61.15704  ? 195 THR A C   1 
ATOM   1319 O  O   . THR A 1 195 ? 16.03410  -2.33325  -37.14484 1.000 63.16092  ? 195 THR A O   1 
ATOM   1320 C  CB  . THR A 1 195 ? 13.24002  -1.57593  -38.67966 1.000 64.31747  ? 195 THR A CB  1 
ATOM   1321 O  OG1 . THR A 1 195 ? 13.80227  -0.35240  -38.18844 1.000 64.31271  ? 195 THR A OG1 1 
ATOM   1322 C  CG2 . THR A 1 195 ? 11.72299  -1.50751  -38.58607 1.000 69.78358  ? 195 THR A CG2 1 
ATOM   1323 N  N   . ASP A 1 196 ? 15.76614  -3.45083  -39.08941 1.000 50.45085  ? 196 ASP A N   1 
ATOM   1324 C  CA  . ASP A 1 196 ? 17.19937  -3.54957  -39.34015 1.000 46.11681  ? 196 ASP A CA  1 
ATOM   1325 C  C   . ASP A 1 196 ? 17.78235  -2.14721  -39.46590 1.000 53.80843  ? 196 ASP A C   1 
ATOM   1326 O  O   . ASP A 1 196 ? 17.49497  -1.44399  -40.44213 1.000 64.03629  ? 196 ASP A O   1 
ATOM   1327 C  CB  . ASP A 1 196 ? 17.47444  -4.37323  -40.60173 1.000 59.91805  ? 196 ASP A CB  1 
ATOM   1328 C  CG  . ASP A 1 196 ? 18.94845  -4.70197  -40.78266 1.000 68.20867  ? 196 ASP A CG  1 
ATOM   1329 O  OD1 . ASP A 1 196 ? 19.79103  -4.12299  -40.06288 1.000 54.68230  ? 196 ASP A OD1 1 
ATOM   1330 O  OD2 . ASP A 1 196 ? 19.26191  -5.54846  -41.64795 1.000 56.30059  ? 196 ASP A OD2 1 
ATOM   1331 N  N   . PRO A 1 197 ? 18.59525  -1.70505  -38.50134 1.000 59.41929  ? 197 PRO A N   1 
ATOM   1332 C  CA  . PRO A 1 197 ? 19.10088  -0.32233  -38.54888 1.000 60.70991  ? 197 PRO A CA  1 
ATOM   1333 C  C   . PRO A 1 197 ? 19.92156  -0.01680  -39.78839 1.000 59.52289  ? 197 PRO A C   1 
ATOM   1334 O  O   . PRO A 1 197 ? 19.86831  1.11255   -40.29219 1.000 56.01642  ? 197 PRO A O   1 
ATOM   1335 C  CB  . PRO A 1 197 ? 19.94337  -0.21446  -37.26735 1.000 44.13969  ? 197 PRO A CB  1 
ATOM   1336 C  CG  . PRO A 1 197 ? 19.45759  -1.32254  -36.38736 1.000 48.03559  ? 197 PRO A CG  1 
ATOM   1337 C  CD  . PRO A 1 197 ? 19.10171  -2.43202  -37.32542 1.000 64.13214  ? 197 PRO A CD  1 
ATOM   1338 N  N   . LEU A 1 198 ? 20.67482  -0.99049  -40.30354 1.000 51.30622  ? 198 LEU A N   1 
ATOM   1339 C  CA  . LEU A 1 198 ? 21.48268  -0.75353  -41.49353 1.000 54.54526  ? 198 LEU A CA  1 
ATOM   1340 C  C   . LEU A 1 198 ? 20.63972  -0.56817  -42.74679 1.000 55.54666  ? 198 LEU A C   1 
ATOM   1341 O  O   . LEU A 1 198 ? 21.17288  -0.12808  -43.77097 1.000 57.25991  ? 198 LEU A O   1 
ATOM   1342 C  CB  . LEU A 1 198 ? 22.47314  -1.90129  -41.70450 1.000 48.43016  ? 198 LEU A CB  1 
ATOM   1343 C  CG  . LEU A 1 198 ? 23.42785  -2.23151  -40.55356 1.000 53.48977  ? 198 LEU A CG  1 
ATOM   1344 C  CD1 . LEU A 1 198 ? 24.57691  -3.09208  -41.05489 1.000 57.44980  ? 198 LEU A CD1 1 
ATOM   1345 C  CD2 . LEU A 1 198 ? 23.94897  -0.96869  -39.88206 1.000 53.88767  ? 198 LEU A CD2 1 
ATOM   1346 N  N   . VAL A 1 199 ? 19.34869  -0.89179  -42.69099 1.000 52.66455  ? 199 VAL A N   1 
ATOM   1347 C  CA  . VAL A 1 199 ? 18.45236  -0.68730  -43.81422 1.000 55.70755  ? 199 VAL A CA  1 
ATOM   1348 C  C   . VAL A 1 199 ? 17.47251  0.45900   -43.57487 1.000 60.33962  ? 199 VAL A C   1 
ATOM   1349 O  O   . VAL A 1 199 ? 17.13813  1.17848   -44.52318 1.000 66.74006  ? 199 VAL A O   1 
ATOM   1350 C  CB  . VAL A 1 199 ? 17.69588  -1.99153  -44.14574 1.000 45.95331  ? 199 VAL A CB  1 
ATOM   1351 C  CG1 . VAL A 1 199 ? 16.82134  -1.81033  -45.37851 1.000 45.22469  ? 199 VAL A CG1 1 
ATOM   1352 C  CG2 . VAL A 1 199 ? 18.67930  -3.13761  -44.34386 1.000 45.16477  ? 199 VAL A CG2 1 
ATOM   1353 N  N   . THR A 1 200 ? 17.01455  0.66074   -42.33955 1.000 50.22377  ? 200 THR A N   1 
ATOM   1354 C  CA  . THR A 1 200 ? 16.03574  1.69825   -42.03945 1.000 56.37871  ? 200 THR A CA  1 
ATOM   1355 C  C   . THR A 1 200 ? 16.67288  3.06364   -41.81567 1.000 60.96872  ? 200 THR A C   1 
ATOM   1356 O  O   . THR A 1 200 ? 16.01715  4.08937   -42.03633 1.000 52.67322  ? 200 THR A O   1 
ATOM   1357 C  CB  . THR A 1 200 ? 15.21755  1.29718   -40.80832 1.000 49.10849  ? 200 THR A CB  1 
ATOM   1358 O  OG1 . THR A 1 200 ? 14.81359  -0.07093  -40.93843 1.000 56.04425  ? 200 THR A OG1 1 
ATOM   1359 C  CG2 . THR A 1 200 ? 13.97242  2.16219   -40.67501 1.000 61.81194  ? 200 THR A CG2 1 
ATOM   1360 N  N   . TYR A 1 201 ? 17.93133  3.09860   -41.38535 1.000 55.00358  ? 201 TYR A N   1 
ATOM   1361 C  CA  . TYR A 1 201 ? 18.67584  4.33970   -41.17842 1.000 48.56899  ? 201 TYR A CA  1 
ATOM   1362 C  C   . TYR A 1 201 ? 20.04512  4.18226   -41.82918 1.000 53.94344  ? 201 TYR A C   1 
ATOM   1363 O  O   . TYR A 1 201 ? 21.07038  4.06007   -41.14769 1.000 46.87086  ? 201 TYR A O   1 
ATOM   1364 C  CB  . TYR A 1 201 ? 18.76541  4.66654   -39.68744 1.000 58.47327  ? 201 TYR A CB  1 
ATOM   1365 C  CG  . TYR A 1 201 ? 17.40481  4.63436   -39.02621 1.000 48.05095  ? 201 TYR A CG  1 
ATOM   1366 C  CD1 . TYR A 1 201 ? 16.53488  5.71214   -39.13190 1.000 50.53909  ? 201 TYR A CD1 1 
ATOM   1367 C  CD2 . TYR A 1 201 ? 16.97369  3.51203   -38.33003 1.000 48.73362  ? 201 TYR A CD2 1 
ATOM   1368 C  CE1 . TYR A 1 201 ? 15.28236  5.68144   -38.54645 1.000 44.11269  ? 201 TYR A CE1 1 
ATOM   1369 C  CE2 . TYR A 1 201 ? 15.72381  3.47223   -37.74176 1.000 52.38339  ? 201 TYR A CE2 1 
ATOM   1370 C  CZ  . TYR A 1 201 ? 14.88272  4.55819   -37.85242 1.000 51.08925  ? 201 TYR A CZ  1 
ATOM   1371 O  OH  . TYR A 1 201 ? 13.63881  4.51533   -37.26498 1.000 73.87062  ? 201 TYR A OH  1 
ATOM   1372 N  N   . PRO A 1 202 ? 20.08799  4.17428   -43.16652 1.000 63.19924  ? 202 PRO A N   1 
ATOM   1373 C  CA  . PRO A 1 202 ? 21.30134  3.71645   -43.86600 1.000 54.24588  ? 202 PRO A CA  1 
ATOM   1374 C  C   . PRO A 1 202 ? 22.52373  4.59774   -43.67285 1.000 54.23399  ? 202 PRO A C   1 
ATOM   1375 O  O   . PRO A 1 202 ? 23.64720  4.09564   -43.80016 1.000 51.56338  ? 202 PRO A O   1 
ATOM   1376 C  CB  . PRO A 1 202 ? 20.86238  3.68781   -45.33703 1.000 49.33464  ? 202 PRO A CB  1 
ATOM   1377 C  CG  . PRO A 1 202 ? 19.72132  4.65006   -45.41087 1.000 61.49237  ? 202 PRO A CG  1 
ATOM   1378 C  CD  . PRO A 1 202 ? 19.00542  4.52291   -44.10252 1.000 60.30607  ? 202 PRO A CD  1 
ATOM   1379 N  N   . SER A 1 203 ? 22.35836  5.88443   -43.38981 1.000 65.53729  ? 203 SER A N   1 
ATOM   1380 C  CA  . SER A 1 203 ? 23.49818  6.77568   -43.23859 1.000 67.20834  ? 203 SER A CA  1 
ATOM   1381 C  C   . SER A 1 203 ? 23.83790  6.95300   -41.76383 1.000 69.29076  ? 203 SER A C   1 
ATOM   1382 O  O   . SER A 1 203 ? 22.98112  6.81042   -40.88752 1.000 73.55444  ? 203 SER A O   1 
ATOM   1383 C  CB  . SER A 1 203 ? 23.22966  8.13719   -43.87995 1.000 59.62946  ? 203 SER A CB  1 
ATOM   1384 O  OG  . SER A 1 203 ? 22.69255  9.04338   -42.93490 1.000 73.21923  ? 203 SER A OG  1 
ATOM   1385 N  N   . LEU A 1 204 ? 25.11252  7.25417   -41.50069 1.000 67.04218  ? 204 LEU A N   1 
ATOM   1386 C  CA  . LEU A 1 204 ? 25.56100  7.47325   -40.12837 1.000 67.43363  ? 204 LEU A CA  1 
ATOM   1387 C  C   . LEU A 1 204 ? 24.78184  8.60255   -39.46917 1.000 66.50970  ? 204 LEU A C   1 
ATOM   1388 O  O   . LEU A 1 204 ? 24.49143  8.55062   -38.26786 1.000 79.11374  ? 204 LEU A O   1 
ATOM   1389 C  CB  . LEU A 1 204 ? 27.06216  7.77032   -40.11389 1.000 61.86483  ? 204 LEU A CB  1 
ATOM   1390 C  CG  . LEU A 1 204 ? 27.73465  8.08136   -38.77504 1.000 56.15122  ? 204 LEU A CG  1 
ATOM   1391 C  CD1 . LEU A 1 204 ? 29.05949  7.34328   -38.64970 1.000 50.59130  ? 204 LEU A CD1 1 
ATOM   1392 C  CD2 . LEU A 1 204 ? 27.94900  9.58048   -38.62735 1.000 58.65227  ? 204 LEU A CD2 1 
ATOM   1393 N  N   . ASP A 1 205 ? 24.44360  9.63604   -40.24048 1.000 66.79035  ? 205 ASP A N   1 
ATOM   1394 C  CA  . ASP A 1 205 ? 23.63032  10.72721  -39.71574 1.000 70.61736  ? 205 ASP A CA  1 
ATOM   1395 C  C   . ASP A 1 205 ? 22.23003  10.24861  -39.34859 1.000 76.02954  ? 205 ASP A C   1 
ATOM   1396 O  O   . ASP A 1 205 ? 21.67173  10.66494  -38.32630 1.000 73.81140  ? 205 ASP A O   1 
ATOM   1397 C  CB  . ASP A 1 205 ? 23.57017  11.85375  -40.74451 1.000 72.80389  ? 205 ASP A CB  1 
ATOM   1398 C  CG  . ASP A 1 205 ? 24.91032  12.09273  -41.41644 1.000 94.49376  ? 205 ASP A CG  1 
ATOM   1399 O  OD1 . ASP A 1 205 ? 25.92300  12.23869  -40.69698 1.000 106.80194 ? 205 ASP A OD1 1 
ATOM   1400 O  OD2 . ASP A 1 205 ? 24.95474  12.10689  -42.66493 1.000 94.58255  ? 205 ASP A OD2 1 
ATOM   1401 N  N   . LYS A 1 206 ? 21.64151  9.38164   -40.17739 1.000 76.76007  ? 206 LYS A N   1 
ATOM   1402 C  CA  . LYS A 1 206 ? 20.28931  8.90269   -39.90561 1.000 63.99800  ? 206 LYS A CA  1 
ATOM   1403 C  C   . LYS A 1 206 ? 20.24766  8.02418   -38.66149 1.000 58.94994  ? 206 LYS A C   1 
ATOM   1404 O  O   . LYS A 1 206 ? 19.34172  8.15977   -37.83092 1.000 65.30846  ? 206 LYS A O   1 
ATOM   1405 C  CB  . LYS A 1 206 ? 19.74318  8.13594   -41.11005 1.000 69.25386  ? 206 LYS A CB  1 
ATOM   1406 C  CG  . LYS A 1 206 ? 19.56376  8.96603   -42.37148 1.000 62.31094  ? 206 LYS A CG  1 
ATOM   1407 C  CD  . LYS A 1 206 ? 19.21782  8.06737   -43.55029 1.000 66.38760  ? 206 LYS A CD  1 
ATOM   1408 C  CE  . LYS A 1 206 ? 19.18791  8.82701   -44.86981 1.000 77.39702  ? 206 LYS A CE  1 
ATOM   1409 N  NZ  . LYS A 1 206 ? 17.87445  9.47648   -45.14025 1.000 70.62219  ? 206 LYS A NZ  1 
ATOM   1410 N  N   . VAL A 1 207 ? 21.21461  7.11520   -38.51517 1.000 63.27677  ? 207 VAL A N   1 
ATOM   1411 C  CA  . VAL A 1 207 ? 21.19190  6.19778   -37.37948 1.000 70.66784  ? 207 VAL A CA  1 
ATOM   1412 C  C   . VAL A 1 207 ? 21.45329  6.94822   -36.07881 1.000 70.71954  ? 207 VAL A C   1 
ATOM   1413 O  O   . VAL A 1 207 ? 20.86806  6.62915   -35.03751 1.000 66.19384  ? 207 VAL A O   1 
ATOM   1414 C  CB  . VAL A 1 207 ? 22.18620  5.03873   -37.59068 1.000 65.69296  ? 207 VAL A CB  1 
ATOM   1415 C  CG1 . VAL A 1 207 ? 23.62194  5.53654   -37.64782 1.000 63.48352  ? 207 VAL A CG1 1 
ATOM   1416 C  CG2 . VAL A 1 207 ? 22.02290  3.99762   -36.49576 1.000 55.73166  ? 207 VAL A CG2 1 
ATOM   1417 N  N   . TRP A 1 208 ? 22.33541  7.95071   -36.10979 1.000 52.33501  ? 208 TRP A N   1 
ATOM   1418 C  CA  . TRP A 1 208 ? 22.50749  8.80714   -34.94422 1.000 49.55851  ? 208 TRP A CA  1 
ATOM   1419 C  C   . TRP A 1 208 ? 21.26938  9.65064   -34.66995 1.000 58.94187  ? 208 TRP A C   1 
ATOM   1420 O  O   . TRP A 1 208 ? 21.06775  10.08037  -33.52910 1.000 54.75891  ? 208 TRP A O   1 
ATOM   1421 C  CB  . TRP A 1 208 ? 23.73431  9.70437   -35.12147 1.000 48.35044  ? 208 TRP A CB  1 
ATOM   1422 C  CG  . TRP A 1 208 ? 25.01224  9.05292   -34.67661 1.000 52.22046  ? 208 TRP A CG  1 
ATOM   1423 C  CD1 . TRP A 1 208 ? 25.89584  8.36278   -35.45392 1.000 63.42804  ? 208 TRP A CD1 1 
ATOM   1424 C  CD2 . TRP A 1 208 ? 25.54307  9.02431   -33.34493 1.000 58.21125  ? 208 TRP A CD2 1 
ATOM   1425 N  NE1 . TRP A 1 208 ? 26.94548  7.90947   -34.69077 1.000 61.72693  ? 208 TRP A NE1 1 
ATOM   1426 C  CE2 . TRP A 1 208 ? 26.75270  8.30231   -33.39253 1.000 66.79673  ? 208 TRP A CE2 1 
ATOM   1427 C  CE3 . TRP A 1 208 ? 25.11370  9.53993   -32.11825 1.000 56.29398  ? 208 TRP A CE3 1 
ATOM   1428 C  CZ2 . TRP A 1 208 ? 27.53726  8.08339   -32.26146 1.000 64.70681  ? 208 TRP A CZ2 1 
ATOM   1429 C  CZ3 . TRP A 1 208 ? 25.89398  9.32109   -30.99628 1.000 62.99513  ? 208 TRP A CZ3 1 
ATOM   1430 C  CH2 . TRP A 1 208 ? 27.09207  8.59934   -31.07614 1.000 64.51128  ? 208 TRP A CH2 1 
ATOM   1431 N  N   . GLY A 1 209 ? 20.44612  9.90750   -35.68824 1.000 53.11137  ? 209 GLY A N   1 
ATOM   1432 C  CA  . GLY A 1 209 ? 19.17429  10.56925  -35.44523 1.000 54.15227  ? 209 GLY A CA  1 
ATOM   1433 C  C   . GLY A 1 209 ? 18.20568  9.69395   -34.67159 1.000 55.60377  ? 209 GLY A C   1 
ATOM   1434 O  O   . GLY A 1 209 ? 17.60380  10.13172  -33.68763 1.000 60.67268  ? 209 GLY A O   1 
ATOM   1435 N  N   . ARG A 1 210 ? 18.04367  8.44079   -35.10594 1.000 60.28569  ? 210 ARG A N   1 
ATOM   1436 C  CA  . ARG A 1 210 ? 17.18548  7.51150   -34.37702 1.000 68.77604  ? 210 ARG A CA  1 
ATOM   1437 C  C   . ARG A 1 210 ? 17.75882  7.20532   -32.99969 1.000 67.41749  ? 210 ARG A C   1 
ATOM   1438 O  O   . ARG A 1 210 ? 17.01197  7.02962   -32.02937 1.000 62.00113  ? 210 ARG A O   1 
ATOM   1439 C  CB  . ARG A 1 210 ? 16.99982  6.22503   -35.18282 1.000 56.19155  ? 210 ARG A CB  1 
ATOM   1440 C  CG  . ARG A 1 210 ? 16.15258  5.17901   -34.48346 1.000 51.93271  ? 210 ARG A CG  1 
ATOM   1441 C  CD  . ARG A 1 210 ? 14.70688  5.62450   -34.37512 1.000 55.92524  ? 210 ARG A CD  1 
ATOM   1442 N  NE  . ARG A 1 210 ? 13.93500  4.75261   -33.49901 1.000 68.75735  ? 210 ARG A NE  1 
ATOM   1443 C  CZ  . ARG A 1 210 ? 13.73239  4.98261   -32.20878 1.000 72.21741  ? 210 ARG A CZ  1 
ATOM   1444 N  NH1 . ARG A 1 210 ? 14.23206  6.05162   -31.61077 1.000 63.70589  ? 210 ARG A NH1 1 
ATOM   1445 N  NH2 . ARG A 1 210 ? 13.00881  4.11955   -31.50121 1.000 79.90586  ? 210 ARG A NH2 1 
ATOM   1446 N  N   . PHE A 1 211 ? 19.08817  7.13792   -32.89936 1.000 61.49328  ? 211 PHE A N   1 
ATOM   1447 C  CA  . PHE A 1 211 ? 19.73669  6.92488   -31.61062 1.000 58.34719  ? 211 PHE A CA  1 
ATOM   1448 C  C   . PHE A 1 211 ? 19.44364  8.07410   -30.65187 1.000 69.00778  ? 211 PHE A C   1 
ATOM   1449 O  O   . PHE A 1 211 ? 19.20425  7.85233   -29.45882 1.000 60.18833  ? 211 PHE A O   1 
ATOM   1450 C  CB  . PHE A 1 211 ? 21.24193  6.75083   -31.82338 1.000 47.16210  ? 211 PHE A CB  1 
ATOM   1451 C  CG  . PHE A 1 211 ? 21.98976  6.29906   -30.60156 1.000 56.29852  ? 211 PHE A CG  1 
ATOM   1452 C  CD1 . PHE A 1 211 ? 21.49945  5.27884   -29.80409 1.000 63.48617  ? 211 PHE A CD1 1 
ATOM   1453 C  CD2 . PHE A 1 211 ? 23.20515  6.87552   -30.27171 1.000 51.39882  ? 211 PHE A CD2 1 
ATOM   1454 C  CE1 . PHE A 1 211 ? 22.19654  4.85915   -28.68578 1.000 61.97592  ? 211 PHE A CE1 1 
ATOM   1455 C  CE2 . PHE A 1 211 ? 23.90740  6.45954   -29.15855 1.000 54.46404  ? 211 PHE A CE2 1 
ATOM   1456 C  CZ  . PHE A 1 211 ? 23.40291  5.45033   -28.36392 1.000 58.14040  ? 211 PHE A CZ  1 
ATOM   1457 N  N   . ASP A 1 212 ? 19.45607  9.31171   -31.15647 1.000 64.56842  ? 212 ASP A N   1 
ATOM   1458 C  CA  . ASP A 1 212 ? 19.13896  10.46108  -30.31357 1.000 56.26879  ? 212 ASP A CA  1 
ATOM   1459 C  C   . ASP A 1 212 ? 17.65661  10.50671  -29.96697 1.000 58.87916  ? 212 ASP A C   1 
ATOM   1460 O  O   . ASP A 1 212 ? 17.28668  10.89179  -28.85103 1.000 70.95697  ? 212 ASP A O   1 
ATOM   1461 C  CB  . ASP A 1 212 ? 19.56418  11.75667  -31.00280 1.000 59.77966  ? 212 ASP A CB  1 
ATOM   1462 C  CG  . ASP A 1 212 ? 21.05584  12.00326  -30.90824 1.000 72.98147  ? 212 ASP A CG  1 
ATOM   1463 O  OD1 . ASP A 1 212 ? 21.67704  11.52043  -29.93843 1.000 67.43943  ? 212 ASP A OD1 1 
ATOM   1464 O  OD2 . ASP A 1 212 ? 21.60585  12.68475  -31.79925 1.000 85.30374  ? 212 ASP A OD2 1 
ATOM   1465 N  N   . LYS A 1 213 ? 16.79207  10.13350  -30.91315 1.000 57.89058  ? 213 LYS A N   1 
ATOM   1466 C  CA  . LYS A 1 213 ? 15.36302  10.08985  -30.62478 1.000 64.22807  ? 213 LYS A CA  1 
ATOM   1467 C  C   . LYS A 1 213 ? 15.06764  9.11489   -29.49472 1.000 70.44366  ? 213 LYS A C   1 
ATOM   1468 O  O   . LYS A 1 213 ? 14.17990  9.35878   -28.67056 1.000 67.80481  ? 213 LYS A O   1 
ATOM   1469 C  CB  . LYS A 1 213 ? 14.58290  9.70589   -31.88377 1.000 56.83130  ? 213 LYS A CB  1 
ATOM   1470 C  CG  . LYS A 1 213 ? 13.08356  9.53747   -31.66938 1.000 68.83987  ? 213 LYS A CG  1 
ATOM   1471 C  CD  . LYS A 1 213 ? 12.41782  10.86236  -31.33552 1.000 77.41937  ? 213 LYS A CD  1 
ATOM   1472 C  CE  . LYS A 1 213 ? 12.40841  11.79408  -32.53832 1.000 83.20901  ? 213 LYS A CE  1 
ATOM   1473 N  NZ  . LYS A 1 213 ? 11.90453  13.15327  -32.19350 1.000 70.83238  ? 213 LYS A NZ  1 
ATOM   1474 N  N   . HIS A 1 214 ? 15.79943  8.00004   -29.45146 1.000 69.36391  ? 214 HIS A N   1 
ATOM   1475 C  CA  . HIS A 1 214 ? 15.60956  7.00160   -28.40439 1.000 67.31953  ? 214 HIS A CA  1 
ATOM   1476 C  C   . HIS A 1 214 ? 15.66403  7.63219   -27.01734 1.000 71.44964  ? 214 HIS A C   1 
ATOM   1477 O  O   . HIS A 1 214 ? 14.78708  7.39649   -26.17800 1.000 71.30188  ? 214 HIS A O   1 
ATOM   1478 C  CB  . HIS A 1 214 ? 16.67076  5.90689   -28.55565 1.000 67.60719  ? 214 HIS A CB  1 
ATOM   1479 C  CG  . HIS A 1 214 ? 16.68616  4.90453   -27.44438 1.000 76.09668  ? 214 HIS A CG  1 
ATOM   1480 N  ND1 . HIS A 1 214 ? 15.81296  3.84051   -27.38385 1.000 75.08096  ? 214 HIS A ND1 1 
ATOM   1481 C  CD2 . HIS A 1 214 ? 17.48764  4.79439   -26.35948 1.000 69.29603  ? 214 HIS A CD2 1 
ATOM   1482 C  CE1 . HIS A 1 214 ? 16.06980  3.12300   -26.30460 1.000 66.65471  ? 214 HIS A CE1 1 
ATOM   1483 N  NE2 . HIS A 1 214 ? 17.08215  3.68052   -25.66571 1.000 58.21124  ? 214 HIS A NE2 1 
ATOM   1484 N  N   . PHE A 1 215 ? 16.68568  8.45223   -26.76501 1.000 61.02940  ? 215 PHE A N   1 
ATOM   1485 C  CA  . PHE A 1 215 ? 16.85428  9.03652   -25.43918 1.000 65.01521  ? 215 PHE A CA  1 
ATOM   1486 C  C   . PHE A 1 215 ? 15.81309  10.11486  -25.16067 1.000 72.66228  ? 215 PHE A C   1 
ATOM   1487 O  O   . PHE A 1 215 ? 15.36623  10.27024  -24.01775 1.000 68.77616  ? 215 PHE A O   1 
ATOM   1488 C  CB  . PHE A 1 215 ? 18.26970  9.58933   -25.29841 1.000 63.20703  ? 215 PHE A CB  1 
ATOM   1489 C  CG  . PHE A 1 215 ? 19.32818  8.52529   -25.24053 1.000 56.06650  ? 215 PHE A CG  1 
ATOM   1490 C  CD1 . PHE A 1 215 ? 19.66519  7.93165   -24.03521 1.000 56.71064  ? 215 PHE A CD1 1 
ATOM   1491 C  CD2 . PHE A 1 215 ? 19.97919  8.11100   -26.39049 1.000 58.83071  ? 215 PHE A CD2 1 
ATOM   1492 C  CE1 . PHE A 1 215 ? 20.63581  6.94966   -23.97716 1.000 55.53890  ? 215 PHE A CE1 1 
ATOM   1493 C  CE2 . PHE A 1 215 ? 20.95097  7.12987   -26.33824 1.000 58.45950  ? 215 PHE A CE2 1 
ATOM   1494 C  CZ  . PHE A 1 215 ? 21.27952  6.54884   -25.13034 1.000 59.27898  ? 215 PHE A CZ  1 
ATOM   1495 N  N   . SER A 1 216 ? 15.41725  10.87255  -26.18694 1.000 64.85612  ? 216 SER A N   1 
ATOM   1496 C  CA  . SER A 1 216 ? 14.40261  11.90211  -25.98663 1.000 63.42979  ? 216 SER A CA  1 
ATOM   1497 C  C   . SER A 1 216 ? 13.02991  11.29344  -25.72701 1.000 68.22449  ? 216 SER A C   1 
ATOM   1498 O  O   . SER A 1 216 ? 12.19165  11.91699  -25.06637 1.000 79.00097  ? 216 SER A O   1 
ATOM   1499 C  CB  . SER A 1 216 ? 14.35213  12.83818  -27.19577 1.000 53.12923  ? 216 SER A CB  1 
ATOM   1500 O  OG  . SER A 1 216 ? 13.68902  12.23106  -28.29067 1.000 77.76462  ? 216 SER A OG  1 
ATOM   1501 N  N   . GLN A 1 217 ? 12.78218  10.08411  -26.23510 1.000 60.90294  ? 217 GLN A N   1 
ATOM   1502 C  CA  . GLN A 1 217 ? 11.51303  9.41498   -25.97091 1.000 66.36323  ? 217 GLN A CA  1 
ATOM   1503 C  C   . GLN A 1 217 ? 11.37058  9.02751   -24.50426 1.000 71.75489  ? 217 GLN A C   1 
ATOM   1504 O  O   . GLN A 1 217 ? 10.25711  9.04301   -23.96711 1.000 71.05146  ? 217 GLN A O   1 
ATOM   1505 C  CB  . GLN A 1 217 ? 11.37424  8.17531   -26.85655 1.000 60.96399  ? 217 GLN A CB  1 
ATOM   1506 C  CG  . GLN A 1 217 ? 11.26807  8.46942   -28.34488 1.000 72.05771  ? 217 GLN A CG  1 
ATOM   1507 C  CD  . GLN A 1 217 ? 11.15505  7.20954   -29.18208 1.000 69.88905  ? 217 GLN A CD  1 
ATOM   1508 O  OE1 . GLN A 1 217 ? 12.15983  6.65103   -29.62010 1.000 71.39258  ? 217 GLN A OE1 1 
ATOM   1509 N  NE2 . GLN A 1 217 ? 9.92809   6.75307   -29.40500 1.000 72.43948  ? 217 GLN A NE2 1 
ATOM   1510 N  N   . LEU A 1 218 ? 12.47565  8.67976   -23.84421 1.000 67.57049  ? 218 LEU A N   1 
ATOM   1511 C  CA  . LEU A 1 218 ? 12.43987  8.12622   -22.49672 1.000 62.09879  ? 218 LEU A CA  1 
ATOM   1512 C  C   . LEU A 1 218 ? 12.84749  9.11134   -21.40909 1.000 77.72230  ? 218 LEU A C   1 
ATOM   1513 O  O   . LEU A 1 218 ? 12.71775  8.77951   -20.22660 1.000 77.61389  ? 218 LEU A O   1 
ATOM   1514 C  CB  . LEU A 1 218 ? 13.35131  6.89579   -22.40414 1.000 56.59490  ? 218 LEU A CB  1 
ATOM   1515 C  CG  . LEU A 1 218 ? 12.97167  5.63074   -23.17448 1.000 58.88005  ? 218 LEU A CG  1 
ATOM   1516 C  CD1 . LEU A 1 218 ? 14.05025  4.57307   -23.01139 1.000 43.82213  ? 218 LEU A CD1 1 
ATOM   1517 C  CD2 . LEU A 1 218 ? 11.63303  5.10366   -22.69414 1.000 60.08405  ? 218 LEU A CD2 1 
ATOM   1518 N  N   . ARG A 1 219 ? 13.33835  10.30130  -21.76666 1.000 82.26640  ? 219 ARG A N   1 
ATOM   1519 C  CA  . ARG A 1 219 ? 13.93996  11.17400  -20.76079 1.000 69.71636  ? 219 ARG A CA  1 
ATOM   1520 C  C   . ARG A 1 219 ? 12.92205  11.61228  -19.71476 1.000 67.71859  ? 219 ARG A C   1 
ATOM   1521 O  O   . ARG A 1 219 ? 13.25414  11.73673  -18.52996 1.000 74.67822  ? 219 ARG A O   1 
ATOM   1522 C  CB  . ARG A 1 219 ? 14.58129  12.39167  -21.42116 1.000 55.00639  ? 219 ARG A CB  1 
ATOM   1523 C  CG  . ARG A 1 219 ? 15.58922  13.08380  -20.52072 1.000 68.48372  ? 219 ARG A CG  1 
ATOM   1524 C  CD  . ARG A 1 219 ? 15.78069  14.54183  -20.88761 1.000 89.22569  ? 219 ARG A CD  1 
ATOM   1525 N  NE  . ARG A 1 219 ? 17.02955  15.06264  -20.34496 1.000 95.96358  ? 219 ARG A NE  1 
ATOM   1526 C  CZ  . ARG A 1 219 ? 17.45846  16.30624  -20.50835 1.000 95.48547  ? 219 ARG A CZ  1 
ATOM   1527 N  NH1 . ARG A 1 219 ? 16.75048  17.19890  -21.18064 1.000 98.12544  ? 219 ARG A NH1 1 
ATOM   1528 N  NH2 . ARG A 1 219 ? 18.62785  16.66288  -19.98479 1.000 107.26238 ? 219 ARG A NH2 1 
ATOM   1529 N  N   . GLY A 1 220 ? 11.67803  11.84682  -20.12850 1.000 61.89765  ? 220 GLY A N   1 
ATOM   1530 C  CA  . GLY A 1 220 ? 10.64853  12.24643  -19.18445 1.000 71.37924  ? 220 GLY A CA  1 
ATOM   1531 C  C   . GLY A 1 220 ? 10.26600  11.17984  -18.17852 1.000 71.20015  ? 220 GLY A C   1 
ATOM   1532 O  O   . GLY A 1 220 ? 9.60700   11.50343  -17.18420 1.000 81.03918  ? 220 GLY A O   1 
ATOM   1533 N  N   . ILE A 1 221 ? 10.66133  9.92943   -18.40748 1.000 70.25630  ? 221 ILE A N   1 
ATOM   1534 C  CA  . ILE A 1 221 ? 10.29536  8.83498   -17.51879 1.000 70.13906  ? 221 ILE A CA  1 
ATOM   1535 C  C   . ILE A 1 221 ? 11.49585  8.19543   -16.83145 1.000 69.57797  ? 221 ILE A C   1 
ATOM   1536 O  O   . ILE A 1 221 ? 11.31975  7.56572   -15.77480 1.000 74.34174  ? 221 ILE A O   1 
ATOM   1537 C  CB  . ILE A 1 221 ? 9.47734   7.76193   -18.27236 1.000 73.20505  ? 221 ILE A CB  1 
ATOM   1538 C  CG1 . ILE A 1 221 ? 8.61664   6.94992   -17.30238 1.000 61.88558  ? 221 ILE A CG1 1 
ATOM   1539 C  CG2 . ILE A 1 221 ? 10.39217  6.83328   -19.06089 1.000 64.77070  ? 221 ILE A CG2 1 
ATOM   1540 C  CD1 . ILE A 1 221 ? 7.66486   5.98976   -17.98219 1.000 60.44713  ? 221 ILE A CD1 1 
ATOM   1541 N  N   . ILE A 1 222 ? 12.71314  8.33231   -17.37047 1.000 67.00187  ? 222 ILE A N   1 
ATOM   1542 C  CA  . ILE A 1 222 ? 13.89093  7.74136   -16.73964 1.000 63.96577  ? 222 ILE A CA  1 
ATOM   1543 C  C   . ILE A 1 222 ? 14.55278  8.69337   -15.75083 1.000 72.45056  ? 222 ILE A C   1 
ATOM   1544 O  O   . ILE A 1 222 ? 15.31231  8.24213   -14.87985 1.000 72.86873  ? 222 ILE A O   1 
ATOM   1545 C  CB  . ILE A 1 222 ? 14.88096  7.26591   -17.82587 1.000 67.02104  ? 222 ILE A CB  1 
ATOM   1546 C  CG1 . ILE A 1 222 ? 14.18388  6.28409   -18.77153 1.000 75.13165  ? 222 ILE A CG1 1 
ATOM   1547 C  CG2 . ILE A 1 222 ? 16.10629  6.59528   -17.21339 1.000 65.84955  ? 222 ILE A CG2 1 
ATOM   1548 C  CD1 . ILE A 1 222 ? 15.13438  5.45350   -19.61824 1.000 78.33105  ? 222 ILE A CD1 1 
ATOM   1549 N  N   . TYR A 1 223 ? 14.25557  9.98798   -15.81643 1.000 69.72372  ? 223 TYR A N   1 
ATOM   1550 C  CA  . TYR A 1 223 ? 14.82011  10.94145  -14.87281 1.000 68.13502  ? 223 TYR A CA  1 
ATOM   1551 C  C   . TYR A 1 223 ? 13.89403  11.24619  -13.70308 1.000 70.92514  ? 223 TYR A C   1 
ATOM   1552 O  O   . TYR A 1 223 ? 14.23218  12.08833  -12.86703 1.000 67.17690  ? 223 TYR A O   1 
ATOM   1553 C  CB  . TYR A 1 223 ? 15.21155  12.23227  -15.59649 1.000 63.51187  ? 223 TYR A CB  1 
ATOM   1554 C  CG  . TYR A 1 223 ? 16.56320  12.11569  -16.25610 1.000 64.97171  ? 223 TYR A CG  1 
ATOM   1555 C  CD1 . TYR A 1 223 ? 16.69941  11.51247  -17.49796 1.000 77.51983  ? 223 TYR A CD1 1 
ATOM   1556 C  CD2 . TYR A 1 223 ? 17.70799  12.58047  -15.62336 1.000 66.85321  ? 223 TYR A CD2 1 
ATOM   1557 C  CE1 . TYR A 1 223 ? 17.93414  11.39057  -18.09959 1.000 78.41169  ? 223 TYR A CE1 1 
ATOM   1558 C  CE2 . TYR A 1 223 ? 18.94786  12.46323  -16.21648 1.000 62.08666  ? 223 TYR A CE2 1 
ATOM   1559 C  CZ  . TYR A 1 223 ? 19.05524  11.86732  -17.45478 1.000 66.69280  ? 223 TYR A CZ  1 
ATOM   1560 O  OH  . TYR A 1 223 ? 20.28751  11.74569  -18.05097 1.000 66.09347  ? 223 TYR A OH  1 
ATOM   1561 N  N   . HIS A 1 224 ? 12.74636  10.57933  -13.61516 1.000 66.35499  ? 224 HIS A N   1 
ATOM   1562 C  CA  . HIS A 1 224 ? 11.93586  10.62489  -12.40624 1.000 58.03143  ? 224 HIS A CA  1 
ATOM   1563 C  C   . HIS A 1 224 ? 12.60333  9.76376   -11.34103 1.000 62.05089  ? 224 HIS A C   1 
ATOM   1564 O  O   . HIS A 1 224 ? 12.88448  8.58499   -11.57755 1.000 71.92070  ? 224 HIS A O   1 
ATOM   1565 C  CB  . HIS A 1 224 ? 10.51686  10.13010  -12.69078 1.000 56.96649  ? 224 HIS A CB  1 
ATOM   1566 C  CG  . HIS A 1 224 ? 9.56075   10.35059  -11.55907 1.000 70.98536  ? 224 HIS A CG  1 
ATOM   1567 N  ND1 . HIS A 1 224 ? 8.47859   9.52904   -11.33064 1.000 68.38446  ? 224 HIS A ND1 1 
ATOM   1568 C  CD2 . HIS A 1 224 ? 9.51644   11.30500  -10.59894 1.000 72.76088  ? 224 HIS A CD2 1 
ATOM   1569 C  CE1 . HIS A 1 224 ? 7.81223   9.96300   -10.27595 1.000 66.06940  ? 224 HIS A CE1 1 
ATOM   1570 N  NE2 . HIS A 1 224 ? 8.42112   11.03968  -9.81324  1.000 73.47360  ? 224 HIS A NE2 1 
ATOM   1571 N  N   . THR A 1 225 ? 12.85724  10.35524  -10.17379 1.000 61.58821  ? 225 THR A N   1 
ATOM   1572 C  CA  . THR A 1 225 ? 13.68663  9.71419   -9.15254  1.000 68.08554  ? 225 THR A CA  1 
ATOM   1573 C  C   . THR A 1 225 ? 13.22763  8.31331   -8.75782  1.000 71.88521  ? 225 THR A C   1 
ATOM   1574 O  O   . THR A 1 225 ? 14.08461  7.41987   -8.66441  1.000 69.62555  ? 225 THR A O   1 
ATOM   1575 C  CB  . THR A 1 225 ? 13.77314  10.62817  -7.92181  1.000 65.20846  ? 225 THR A CB  1 
ATOM   1576 O  OG1 . THR A 1 225 ? 14.35680  11.88321  -8.29297  1.000 70.63293  ? 225 THR A OG1 1 
ATOM   1577 C  CG2 . THR A 1 225 ? 14.62467  9.98623   -6.83407  1.000 83.06611  ? 225 THR A CG2 1 
ATOM   1578 N  N   . PRO A 1 226 ? 11.93920  8.04212   -8.50371  1.000 67.08313  ? 226 PRO A N   1 
ATOM   1579 C  CA  . PRO A 1 226 ? 11.56248  6.65090   -8.18243  1.000 66.45094  ? 226 PRO A CA  1 
ATOM   1580 C  C   . PRO A 1 226 ? 11.85327  5.68162   -9.31372  1.000 70.84433  ? 226 PRO A C   1 
ATOM   1581 O  O   . PRO A 1 226 ? 12.38409  4.58945   -9.07519  1.000 72.46522  ? 226 PRO A O   1 
ATOM   1582 C  CB  . PRO A 1 226 ? 10.05880  6.75293   -7.88385  1.000 59.90118  ? 226 PRO A CB  1 
ATOM   1583 C  CG  . PRO A 1 226 ? 9.82016   8.18103   -7.57126  1.000 77.35025  ? 226 PRO A CG  1 
ATOM   1584 C  CD  . PRO A 1 226 ? 10.77539  8.94240   -8.42868  1.000 73.46103  ? 226 PRO A CD  1 
ATOM   1585 N  N   . ILE A 1 227 ? 11.52530  6.06207   -10.54980 1.000 71.40039  ? 227 ILE A N   1 
ATOM   1586 C  CA  . ILE A 1 227 ? 11.75614  5.18068   -11.68843 1.000 59.17993  ? 227 ILE A CA  1 
ATOM   1587 C  C   . ILE A 1 227 ? 13.24683  4.98333   -11.93417 1.000 61.16643  ? 227 ILE A C   1 
ATOM   1588 O  O   . ILE A 1 227 ? 13.67385  3.90334   -12.35596 1.000 67.31121  ? 227 ILE A O   1 
ATOM   1589 C  CB  . ILE A 1 227 ? 11.03457  5.73214   -12.93115 1.000 60.23891  ? 227 ILE A CB  1 
ATOM   1590 C  CG1 . ILE A 1 227 ? 9.55897   5.98262   -12.60143 1.000 65.67763  ? 227 ILE A CG1 1 
ATOM   1591 C  CG2 . ILE A 1 227 ? 11.16834  4.76969   -14.09998 1.000 60.24399  ? 227 ILE A CG2 1 
ATOM   1592 C  CD1 . ILE A 1 227 ? 8.73083   6.46184   -13.77054 1.000 67.98683  ? 227 ILE A CD1 1 
ATOM   1593 N  N   . ARG A 1 228 ? 14.06112  6.01032   -11.68572 1.000 58.21162  ? 228 ARG A N   1 
ATOM   1594 C  CA  . ARG A 1 228 ? 15.49382  5.88556   -11.93411 1.000 55.30474  ? 228 ARG A CA  1 
ATOM   1595 C  C   . ARG A 1 228 ? 16.16993  5.00769   -10.88867 1.000 62.60484  ? 228 ARG A C   1 
ATOM   1596 O  O   . ARG A 1 228 ? 17.04694  4.20186   -11.22307 1.000 66.95545  ? 228 ARG A O   1 
ATOM   1597 C  CB  . ARG A 1 228 ? 16.15421  7.25967   -11.96935 1.000 59.49726  ? 228 ARG A CB  1 
ATOM   1598 C  CG  . ARG A 1 228 ? 17.67142  7.19383   -12.00151 1.000 57.78950  ? 228 ARG A CG  1 
ATOM   1599 C  CD  . ARG A 1 228 ? 18.18718  6.64933   -13.32205 1.000 64.95060  ? 228 ARG A CD  1 
ATOM   1600 N  NE  . ARG A 1 228 ? 17.99006  7.59203   -14.41669 1.000 63.18663  ? 228 ARG A NE  1 
ATOM   1601 C  CZ  . ARG A 1 228 ? 18.93096  8.38848   -14.90588 1.000 62.01743  ? 228 ARG A CZ  1 
ATOM   1602 N  NH1 . ARG A 1 228 ? 20.16637  8.37094   -14.43643 1.000 51.82439  ? 228 ARG A NH1 1 
ATOM   1603 N  NH2 . ARG A 1 228 ? 18.62434  9.22297   -15.89339 1.000 72.25036  ? 228 ARG A NH2 1 
ATOM   1604 N  N   . ARG A 1 229 ? 15.79175  5.15761   -9.61562  1.000 59.86480  ? 229 ARG A N   1 
ATOM   1605 C  CA  . ARG A 1 229 ? 16.40500  4.34175   -8.57223  1.000 71.11631  ? 229 ARG A CA  1 
ATOM   1606 C  C   . ARG A 1 229 ? 16.12932  2.86444   -8.80966  1.000 69.36665  ? 229 ARG A C   1 
ATOM   1607 O  O   . ARG A 1 229 ? 16.99338  2.01393   -8.56644  1.000 62.78800  ? 229 ARG A O   1 
ATOM   1608 C  CB  . ARG A 1 229 ? 15.89442  4.75793   -7.19229  1.000 78.07721  ? 229 ARG A CB  1 
ATOM   1609 C  CG  . ARG A 1 229 ? 16.86738  4.40923   -6.07291  1.000 76.64892  ? 229 ARG A CG  1 
ATOM   1610 C  CD  . ARG A 1 229 ? 16.17889  3.85008   -4.83623  1.000 66.52928  ? 229 ARG A CD  1 
ATOM   1611 N  NE  . ARG A 1 229 ? 15.75112  2.47086   -5.04290  1.000 98.20908  ? 229 ARG A NE  1 
ATOM   1612 C  CZ  . ARG A 1 229 ? 15.19497  1.70090   -4.11662  1.000 106.47936 ? 229 ARG A CZ  1 
ATOM   1613 N  NH1 . ARG A 1 229 ? 14.95522  2.14816   -2.89468  1.000 98.78117  ? 229 ARG A NH1 1 
ATOM   1614 N  NH2 . ARG A 1 229 ? 14.87494  0.44775   -4.42382  1.000 94.24912  ? 229 ARG A NH2 1 
ATOM   1615 N  N   . ASP A 1 230 ? 14.92599  2.54204   -9.28218  1.000 60.30114  ? 230 ASP A N   1 
ATOM   1616 C  CA  . ASP A 1 230 ? 14.59855  1.16786   -9.63167  1.000 63.03020  ? 230 ASP A CA  1 
ATOM   1617 C  C   . ASP A 1 230 ? 15.25138  0.74227   -10.94198 1.000 71.84217  ? 230 ASP A C   1 
ATOM   1618 O  O   . ASP A 1 230 ? 15.60980  -0.43091  -11.09513 1.000 73.47876  ? 230 ASP A O   1 
ATOM   1619 C  CB  . ASP A 1 230 ? 13.07995  1.00167   -9.70791  1.000 65.73939  ? 230 ASP A CB  1 
ATOM   1620 C  CG  . ASP A 1 230 ? 12.39446  1.27797   -8.37975  1.000 67.26075  ? 230 ASP A CG  1 
ATOM   1621 O  OD1 . ASP A 1 230 ? 13.09864  1.36216   -7.35166  1.000 74.77864  ? 230 ASP A OD1 1 
ATOM   1622 O  OD2 . ASP A 1 230 ? 11.15380  1.41491   -8.36054  1.000 62.49209  ? 230 ASP A OD2 1 
ATOM   1623 N  N   . TYR A 1 231 ? 15.41305  1.66806   -11.89205 1.000 68.90113  ? 231 TYR A N   1 
ATOM   1624 C  CA  . TYR A 1 231 ? 16.07049  1.32586   -13.15015 1.000 73.82192  ? 231 TYR A CA  1 
ATOM   1625 C  C   . TYR A 1 231 ? 17.54209  0.99195   -12.93656 1.000 78.25727  ? 231 TYR A C   1 
ATOM   1626 O  O   . TYR A 1 231 ? 18.06349  0.05277   -13.54876 1.000 72.46672  ? 231 TYR A O   1 
ATOM   1627 C  CB  . TYR A 1 231 ? 15.92320  2.46930   -14.15662 1.000 71.07063  ? 231 TYR A CB  1 
ATOM   1628 C  CG  . TYR A 1 231 ? 16.46470  2.14845   -15.53589 1.000 72.44759  ? 231 TYR A CG  1 
ATOM   1629 C  CD1 . TYR A 1 231 ? 15.68061  1.48873   -16.47457 1.000 71.61054  ? 231 TYR A CD1 1 
ATOM   1630 C  CD2 . TYR A 1 231 ? 17.75641  2.50884   -15.89971 1.000 63.26797  ? 231 TYR A CD2 1 
ATOM   1631 C  CE1 . TYR A 1 231 ? 16.16898  1.19430   -17.73416 1.000 67.87123  ? 231 TYR A CE1 1 
ATOM   1632 C  CE2 . TYR A 1 231 ? 18.25320  2.21794   -17.15644 1.000 61.12921  ? 231 TYR A CE2 1 
ATOM   1633 C  CZ  . TYR A 1 231 ? 17.45432  1.56287   -18.06975 1.000 67.83800  ? 231 TYR A CZ  1 
ATOM   1634 O  OH  . TYR A 1 231 ? 17.94312  1.26892   -19.32179 1.000 60.88562  ? 231 TYR A OH  1 
ATOM   1635 N  N   . TYR A 1 232 ? 18.23300  1.75524   -12.08540 1.000 69.75978  ? 232 TYR A N   1 
ATOM   1636 C  CA  . TYR A 1 232 ? 19.65055  1.49347   -11.85792 1.000 54.71507  ? 232 TYR A CA  1 
ATOM   1637 C  C   . TYR A 1 232 ? 19.86539  0.12600   -11.22596 1.000 66.41746  ? 232 TYR A C   1 
ATOM   1638 O  O   . TYR A 1 232 ? 20.81973  -0.58065  -11.57115 1.000 69.06695  ? 232 TYR A O   1 
ATOM   1639 C  CB  . TYR A 1 232 ? 20.27076  2.58055   -10.98210 1.000 62.18716  ? 232 TYR A CB  1 
ATOM   1640 C  CG  . TYR A 1 232 ? 21.72641  2.31255   -10.66322 1.000 64.77585  ? 232 TYR A CG  1 
ATOM   1641 C  CD1 . TYR A 1 232 ? 22.72418  2.60212   -11.58641 1.000 53.41352  ? 232 TYR A CD1 1 
ATOM   1642 C  CD2 . TYR A 1 232 ? 22.10162  1.75708   -9.44576  1.000 57.48804  ? 232 TYR A CD2 1 
ATOM   1643 C  CE1 . TYR A 1 232 ? 24.05418  2.35242   -11.30289 1.000 57.04834  ? 232 TYR A CE1 1 
ATOM   1644 C  CE2 . TYR A 1 232 ? 23.42807  1.50384   -9.15480  1.000 53.02928  ? 232 TYR A CE2 1 
ATOM   1645 C  CZ  . TYR A 1 232 ? 24.39949  1.80339   -10.08629 1.000 57.59329  ? 232 TYR A CZ  1 
ATOM   1646 O  OH  . TYR A 1 232 ? 25.72171  1.55339   -9.79986  1.000 50.64127  ? 232 TYR A OH  1 
ATOM   1647 N  N   . ARG A 1 233 ? 19.00533  -0.25790  -10.27944 1.000 67.21278  ? 233 ARG A N   1 
ATOM   1648 C  CA  . ARG A 1 233 ? 19.12262  -1.59392  -9.70824  1.000 66.57854  ? 233 ARG A CA  1 
ATOM   1649 C  C   . ARG A 1 233 ? 18.89596  -2.65972  -10.76989 1.000 58.96514  ? 233 ARG A C   1 
ATOM   1650 O  O   . ARG A 1 233 ? 19.54881  -3.71010  -10.75455 1.000 55.81757  ? 233 ARG A O   1 
ATOM   1651 C  CB  . ARG A 1 233 ? 18.14582  -1.78998  -8.55001  1.000 51.26738  ? 233 ARG A CB  1 
ATOM   1652 C  CG  . ARG A 1 233 ? 18.38941  -3.12135  -7.86566  1.000 48.20979  ? 233 ARG A CG  1 
ATOM   1653 C  CD  . ARG A 1 233 ? 17.26964  -3.59170  -6.96767  1.000 66.13712  ? 233 ARG A CD  1 
ATOM   1654 N  NE  . ARG A 1 233 ? 17.43153  -5.01530  -6.69635  1.000 79.25460  ? 233 ARG A NE  1 
ATOM   1655 C  CZ  . ARG A 1 233 ? 18.33778  -5.52451  -5.87180  1.000 80.18516  ? 233 ARG A CZ  1 
ATOM   1656 N  NH1 . ARG A 1 233 ? 19.16396  -4.74994  -5.18727  1.000 74.78191  ? 233 ARG A NH1 1 
ATOM   1657 N  NH2 . ARG A 1 233 ? 18.42038  -6.84496  -5.73380  1.000 80.45891  ? 233 ARG A NH2 1 
ATOM   1658 N  N   . GLN A 1 234 ? 17.97378  -2.40715  -11.70196 1.000 59.72618  ? 234 GLN A N   1 
ATOM   1659 C  CA  . GLN A 1 234 ? 17.75837  -3.34658  -12.79601 1.000 60.79275  ? 234 GLN A CA  1 
ATOM   1660 C  C   . GLN A 1 234 ? 19.02893  -3.55279  -13.61502 1.000 61.04125  ? 234 GLN A C   1 
ATOM   1661 O  O   . GLN A 1 234 ? 19.26424  -4.65300  -14.12564 1.000 54.09028  ? 234 GLN A O   1 
ATOM   1662 C  CB  . GLN A 1 234 ? 16.61967  -2.84988  -13.68851 1.000 52.44158  ? 234 GLN A CB  1 
ATOM   1663 C  CG  . GLN A 1 234 ? 15.76205  -3.96675  -14.25181 1.000 62.50250  ? 234 GLN A CG  1 
ATOM   1664 C  CD  . GLN A 1 234 ? 15.01517  -4.71901  -13.16412 1.000 81.45553  ? 234 GLN A CD  1 
ATOM   1665 O  OE1 . GLN A 1 234 ? 14.62764  -4.13766  -12.14994 1.000 83.64027  ? 234 GLN A OE1 1 
ATOM   1666 N  NE2 . GLN A 1 234 ? 14.82330  -6.01989  -13.36239 1.000 89.30149  ? 234 GLN A NE2 1 
ATOM   1667 N  N   . ILE A 1 235 ? 19.86154  -2.51448  -13.74336 1.000 61.31524  ? 235 ILE A N   1 
ATOM   1668 C  CA  . ILE A 1 235 ? 21.14805  -2.66264  -14.42465 1.000 55.67394  ? 235 ILE A CA  1 
ATOM   1669 C  C   . ILE A 1 235 ? 22.02509  -3.67008  -13.69216 1.000 63.77222  ? 235 ILE A C   1 
ATOM   1670 O  O   . ILE A 1 235 ? 22.56884  -4.60337  -14.29571 1.000 60.71411  ? 235 ILE A O   1 
ATOM   1671 C  CB  . ILE A 1 235 ? 21.85312  -1.29881  -14.54840 1.000 52.25830  ? 235 ILE A CB  1 
ATOM   1672 C  CG1 . ILE A 1 235 ? 21.11570  -0.39083  -15.53439 1.000 52.03535  ? 235 ILE A CG1 1 
ATOM   1673 C  CG2 . ILE A 1 235 ? 23.31477  -1.47443  -14.95960 1.000 43.30154  ? 235 ILE A CG2 1 
ATOM   1674 C  CD1 . ILE A 1 235 ? 21.70875  0.99730   -15.63699 1.000 44.35359  ? 235 ILE A CD1 1 
ATOM   1675 N  N   . LEU A 1 236 ? 22.17848  -3.49236  -12.37707 1.000 65.62291  ? 236 LEU A N   1 
ATOM   1676 C  CA  . LEU A 1 236 ? 23.01660  -4.39836  -11.59666 1.000 64.90385  ? 236 LEU A CA  1 
ATOM   1677 C  C   . LEU A 1 236 ? 22.43056  -5.80628  -11.56085 1.000 62.79126  ? 236 LEU A C   1 
ATOM   1678 O  O   . LEU A 1 236 ? 23.16641  -6.79480  -11.66296 1.000 52.87229  ? 236 LEU A O   1 
ATOM   1679 C  CB  . LEU A 1 236 ? 23.19516  -3.85373  -10.17882 1.000 58.02821  ? 236 LEU A CB  1 
ATOM   1680 C  CG  . LEU A 1 236 ? 23.79776  -2.45377  -10.03414 1.000 44.96917  ? 236 LEU A CG  1 
ATOM   1681 C  CD1 . LEU A 1 236 ? 23.87013  -2.05928  -8.57019  1.000 47.62050  ? 236 LEU A CD1 1 
ATOM   1682 C  CD2 . LEU A 1 236 ? 25.17542  -2.38636  -10.66968 1.000 38.39769  ? 236 LEU A CD2 1 
ATOM   1683 N  N   . GLU A 1 237 ? 21.10758  -5.91397  -11.41665 1.000 65.36014  ? 237 GLU A N   1 
ATOM   1684 C  CA  . GLU A 1 237 ? 20.45821  -7.22030  -11.36823 1.000 65.24241  ? 237 GLU A CA  1 
ATOM   1685 C  C   . GLU A 1 237 ? 20.61264  -7.97243  -12.68351 1.000 70.15407  ? 237 GLU A C   1 
ATOM   1686 O  O   . GLU A 1 237 ? 20.73452  -9.20289  -12.68464 1.000 79.32040  ? 237 GLU A O   1 
ATOM   1687 C  CB  . GLU A 1 237 ? 18.97673  -7.05120  -11.01842 1.000 67.03520  ? 237 GLU A CB  1 
ATOM   1688 C  CG  . GLU A 1 237 ? 18.17602  -8.34758  -10.98584 1.000 89.55509  ? 237 GLU A CG  1 
ATOM   1689 C  CD  . GLU A 1 237 ? 18.47270  -9.19063  -9.76001  1.000 98.77909  ? 237 GLU A CD  1 
ATOM   1690 O  OE1 . GLU A 1 237 ? 18.29487  -8.68217  -8.63159  1.000 101.22793 ? 237 GLU A OE1 1 
ATOM   1691 O  OE2 . GLU A 1 237 ? 18.88980  -10.35761 -9.92642  1.000 81.30570  ? 237 GLU A OE2 1 
ATOM   1692 N  N   . GLU A 1 238 ? 20.60676  -7.25679  -13.80969 1.000 61.76622  ? 238 GLU A N   1 
ATOM   1693 C  CA  . GLU A 1 238 ? 20.74814  -7.91039  -15.10584 1.000 61.55889  ? 238 GLU A CA  1 
ATOM   1694 C  C   . GLU A 1 238 ? 22.20012  -8.24374  -15.42428 1.000 59.29982  ? 238 GLU A C   1 
ATOM   1695 O  O   . GLU A 1 238 ? 22.48286  -9.30487  -15.99119 1.000 69.07582  ? 238 GLU A O   1 
ATOM   1696 C  CB  . GLU A 1 238 ? 20.16237  -7.02993  -16.20573 1.000 64.33077  ? 238 GLU A CB  1 
ATOM   1697 C  CG  . GLU A 1 238 ? 18.65387  -6.95806  -16.19396 1.000 74.29919  ? 238 GLU A CG  1 
ATOM   1698 C  CD  . GLU A 1 238 ? 18.11811  -6.09261  -17.30755 1.000 79.69059  ? 238 GLU A CD  1 
ATOM   1699 O  OE1 . GLU A 1 238 ? 18.93203  -5.61271  -18.12563 1.000 73.53925  ? 238 GLU A OE1 1 
ATOM   1700 O  OE2 . GLU A 1 238 ? 16.88711  -5.89010  -17.36213 1.000 82.79967  ? 238 GLU A OE2 1 
ATOM   1701 N  N   . PHE A 1 239 ? 23.13243  -7.35249  -15.08037 1.000 58.05560  ? 239 PHE A N   1 
ATOM   1702 C  CA  . PHE A 1 239 ? 24.52916  -7.59325  -15.42707 1.000 57.79897  ? 239 PHE A CA  1 
ATOM   1703 C  C   . PHE A 1 239 ? 25.12607  -8.72945  -14.60973 1.000 63.46151  ? 239 PHE A C   1 
ATOM   1704 O  O   . PHE A 1 239 ? 26.03236  -9.42140  -15.08566 1.000 66.60282  ? 239 PHE A O   1 
ATOM   1705 C  CB  . PHE A 1 239 ? 25.34517  -6.31383  -15.25474 1.000 57.88974  ? 239 PHE A CB  1 
ATOM   1706 C  CG  . PHE A 1 239 ? 25.50307  -5.52859  -16.52514 1.000 64.60111  ? 239 PHE A CG  1 
ATOM   1707 C  CD1 . PHE A 1 239 ? 24.41388  -4.90091  -17.10610 1.000 60.97440  ? 239 PHE A CD1 1 
ATOM   1708 C  CD2 . PHE A 1 239 ? 26.73892  -5.42392  -17.14193 1.000 63.62256  ? 239 PHE A CD2 1 
ATOM   1709 C  CE1 . PHE A 1 239 ? 24.55362  -4.18194  -18.27666 1.000 55.85932  ? 239 PHE A CE1 1 
ATOM   1710 C  CE2 . PHE A 1 239 ? 26.88532  -4.70671  -18.31261 1.000 55.77660  ? 239 PHE A CE2 1 
ATOM   1711 C  CZ  . PHE A 1 239 ? 25.79069  -4.08423  -18.88072 1.000 57.23143  ? 239 PHE A CZ  1 
ATOM   1712 N  N   . ARG A 1 240 ? 24.64121  -8.93892  -13.38533 1.000 64.26240  ? 240 ARG A N   1 
ATOM   1713 C  CA  . ARG A 1 240 ? 25.06134  -10.11592 -12.63385 1.000 61.79827  ? 240 ARG A CA  1 
ATOM   1714 C  C   . ARG A 1 240 ? 24.39868  -11.37468 -13.17943 1.000 66.91754  ? 240 ARG A C   1 
ATOM   1715 O  O   . ARG A 1 240 ? 25.00305  -12.45363 -13.17389 1.000 76.57719  ? 240 ARG A O   1 
ATOM   1716 C  CB  . ARG A 1 240 ? 24.74727  -9.94167  -11.15014 1.000 57.18495  ? 240 ARG A CB  1 
ATOM   1717 C  CG  . ARG A 1 240 ? 25.48667  -10.92266 -10.25657 1.000 69.52498  ? 240 ARG A CG  1 
ATOM   1718 C  CD  . ARG A 1 240 ? 24.99257  -10.85995 -8.82366  1.000 67.73806  ? 240 ARG A CD  1 
ATOM   1719 N  NE  . ARG A 1 240 ? 24.22315  -12.04451 -8.46642  1.000 63.00787  ? 240 ARG A NE  1 
ATOM   1720 C  CZ  . ARG A 1 240 ? 22.90092  -12.12256 -8.52212  1.000 71.36798  ? 240 ARG A CZ  1 
ATOM   1721 N  NH1 . ARG A 1 240 ? 22.16353  -11.09363 -8.90646  1.000 73.20455  ? 240 ARG A NH1 1 
ATOM   1722 N  NH2 . ARG A 1 240 ? 22.30299  -13.25981 -8.17787  1.000 73.10793  ? 240 ARG A NH2 1 
ATOM   1723 N  N   . SER A 1 241 ? 23.15635  -11.25548 -13.65725 1.000 65.22140  ? 241 SER A N   1 
ATOM   1724 C  CA  . SER A 1 241 ? 22.46844  -12.38167 -14.27787 1.000 56.48652  ? 241 SER A CA  1 
ATOM   1725 C  C   . SER A 1 241 ? 23.07788  -12.76897 -15.61686 1.000 68.33181  ? 241 SER A C   1 
ATOM   1726 O  O   . SER A 1 241 ? 22.70716  -13.81008 -16.17085 1.000 82.47018  ? 241 SER A O   1 
ATOM   1727 C  CB  . SER A 1 241 ? 20.98244  -12.06268 -14.45662 1.000 55.26956  ? 241 SER A CB  1 
ATOM   1728 O  OG  . SER A 1 241 ? 20.34399  -11.90739 -13.20122 1.000 64.38285  ? 241 SER A OG  1 
ATOM   1729 N  N   . ASP A 1 242 ? 23.98384  -11.95135 -16.15298 1.000 64.36181  ? 242 ASP A N   1 
ATOM   1730 C  CA  . ASP A 1 242 ? 24.79974  -12.31646 -17.30177 1.000 64.52001  ? 242 ASP A CA  1 
ATOM   1731 C  C   . ASP A 1 242 ? 26.23529  -12.63010 -16.88953 1.000 73.10105  ? 242 ASP A C   1 
ATOM   1732 O  O   . ASP A 1 242 ? 27.15039  -12.54201 -17.71343 1.000 74.02183  ? 242 ASP A O   1 
ATOM   1733 C  CB  . ASP A 1 242 ? 24.76566  -11.20451 -18.35111 1.000 64.21987  ? 242 ASP A CB  1 
ATOM   1734 C  CG  . ASP A 1 242 ? 25.14232  -11.69668 -19.73420 1.000 82.39539  ? 242 ASP A CG  1 
ATOM   1735 O  OD1 . ASP A 1 242 ? 24.54470  -12.69578 -20.18954 1.000 75.39894  ? 242 ASP A OD1 1 
ATOM   1736 O  OD2 . ASP A 1 242 ? 26.02994  -11.08140 -20.36350 1.000 77.45315  ? 242 ASP A OD2 1 
ATOM   1737 N  N   . ASN A 1 243 ? 26.44252  -12.97753 -15.61662 1.000 65.21231  ? 243 ASN A N   1 
ATOM   1738 C  CA  . ASN A 1 243 ? 27.74288  -13.40083 -15.09053 1.000 69.19219  ? 243 ASN A CA  1 
ATOM   1739 C  C   . ASN A 1 243 ? 28.81851  -12.33312 -15.28508 1.000 70.69731  ? 243 ASN A C   1 
ATOM   1740 O  O   . ASN A 1 243 ? 29.97974  -12.63683 -15.56560 1.000 70.81397  ? 243 ASN A O   1 
ATOM   1741 C  CB  . ASN A 1 243 ? 28.17506  -14.73487 -15.70192 1.000 63.50088  ? 243 ASN A CB  1 
ATOM   1742 C  CG  . ASN A 1 243 ? 27.25525  -15.87415 -15.31116 1.000 68.64272  ? 243 ASN A CG  1 
ATOM   1743 O  OD1 . ASN A 1 243 ? 26.76386  -16.61089 -16.16283 1.000 75.90739  ? 243 ASN A OD1 1 
ATOM   1744 N  ND2 . ASN A 1 243 ? 27.00963  -16.01701 -14.01392 1.000 77.05910  ? 243 ASN A ND2 1 
ATOM   1745 N  N   . VAL A 1 244 ? 28.43005  -11.07083 -15.13082 1.000 69.42293  ? 244 VAL A N   1 
ATOM   1746 C  CA  . VAL A 1 244 ? 29.36328  -9.95356  -15.05199 1.000 72.91215  ? 244 VAL A CA  1 
ATOM   1747 C  C   . VAL A 1 244 ? 29.32322  -9.42580  -13.62573 1.000 74.41419  ? 244 VAL A C   1 
ATOM   1748 O  O   . VAL A 1 244 ? 28.24232  -9.15406  -13.08869 1.000 72.02030  ? 244 VAL A O   1 
ATOM   1749 C  CB  . VAL A 1 244 ? 29.02227  -8.84805  -16.06540 1.000 70.14418  ? 244 VAL A CB  1 
ATOM   1750 C  CG1 . VAL A 1 244 ? 30.11069  -7.78705  -16.07375 1.000 67.93371  ? 244 VAL A CG1 1 
ATOM   1751 C  CG2 . VAL A 1 244 ? 28.83647  -9.44165  -17.45201 1.000 79.51443  ? 244 VAL A CG2 1 
ATOM   1752 N  N   . GLN A 1 245 ? 30.49613  -9.29076  -13.00982 1.000 73.30577  ? 245 GLN A N   1 
ATOM   1753 C  CA  . GLN A 1 245 ? 30.58692  -8.99586  -11.58839 1.000 72.62198  ? 245 GLN A CA  1 
ATOM   1754 C  C   . GLN A 1 245 ? 31.01021  -7.56775  -11.27628 1.000 72.00132  ? 245 GLN A C   1 
ATOM   1755 O  O   . GLN A 1 245 ? 30.97225  -7.17551  -10.10568 1.000 76.35818  ? 245 GLN A O   1 
ATOM   1756 C  CB  . GLN A 1 245 ? 31.56451  -9.97158  -10.91659 1.000 81.21748  ? 245 GLN A CB  1 
ATOM   1757 C  CG  . GLN A 1 245 ? 31.21794  -11.43615 -11.14254 1.000 77.88081  ? 245 GLN A CG  1 
ATOM   1758 C  CD  . GLN A 1 245 ? 32.44612  -12.32034 -11.22141 1.000 84.46749  ? 245 GLN A CD  1 
ATOM   1759 O  OE1 . GLN A 1 245 ? 33.09355  -12.59705 -10.21193 1.000 74.19554  ? 245 GLN A OE1 1 
ATOM   1760 N  NE2 . GLN A 1 245 ? 32.77623  -12.76565 -12.42843 1.000 85.80953  ? 245 GLN A NE2 1 
ATOM   1761 N  N   . TYR A 1 246 ? 31.39662  -6.77956  -12.27681 1.000 79.78864  ? 246 TYR A N   1 
ATOM   1762 C  CA  . TYR A 1 246 ? 31.91728  -5.44182  -12.03546 1.000 73.83293  ? 246 TYR A CA  1 
ATOM   1763 C  C   . TYR A 1 246 ? 31.55219  -4.54215  -13.20658 1.000 66.04981  ? 246 TYR A C   1 
ATOM   1764 O  O   . TYR A 1 246 ? 31.61865  -4.96409  -14.36368 1.000 63.73456  ? 246 TYR A O   1 
ATOM   1765 C  CB  . TYR A 1 246 ? 33.43625  -5.48114  -11.83313 1.000 71.47327  ? 246 TYR A CB  1 
ATOM   1766 C  CG  . TYR A 1 246 ? 34.07870  -4.13348  -11.62212 1.000 63.69619  ? 246 TYR A CG  1 
ATOM   1767 C  CD1 . TYR A 1 246 ? 33.95661  -3.46562  -10.41207 1.000 69.31970  ? 246 TYR A CD1 1 
ATOM   1768 C  CD2 . TYR A 1 246 ? 34.82579  -3.53729  -12.62870 1.000 67.87516  ? 246 TYR A CD2 1 
ATOM   1769 C  CE1 . TYR A 1 246 ? 34.54936  -2.23534  -10.21567 1.000 78.59398  ? 246 TYR A CE1 1 
ATOM   1770 C  CE2 . TYR A 1 246 ? 35.42392  -2.31012  -12.44190 1.000 67.59972  ? 246 TYR A CE2 1 
ATOM   1771 C  CZ  . TYR A 1 246 ? 35.28199  -1.66245  -11.23414 1.000 77.90661  ? 246 TYR A CZ  1 
ATOM   1772 O  OH  . TYR A 1 246 ? 35.87446  -0.43767  -11.03970 1.000 76.29799  ? 246 TYR A OH  1 
ATOM   1773 N  N   . VAL A 1 247 ? 31.15758  -3.30743  -12.90091 1.000 70.18410  ? 247 VAL A N   1 
ATOM   1774 C  CA  . VAL A 1 247 ? 30.75170  -2.34297  -13.91849 1.000 72.69702  ? 247 VAL A CA  1 
ATOM   1775 C  C   . VAL A 1 247 ? 31.32249  -0.97460  -13.56717 1.000 68.28323  ? 247 VAL A C   1 
ATOM   1776 O  O   . VAL A 1 247 ? 31.41908  -0.61123  -12.38992 1.000 69.44759  ? 247 VAL A O   1 
ATOM   1777 C  CB  . VAL A 1 247 ? 29.21329  -2.27217  -14.06669 1.000 61.24385  ? 247 VAL A CB  1 
ATOM   1778 C  CG1 . VAL A 1 247 ? 28.66165  -3.57831  -14.62699 1.000 73.06600  ? 247 VAL A CG1 1 
ATOM   1779 C  CG2 . VAL A 1 247 ? 28.55379  -1.94185  -12.73877 1.000 61.53885  ? 247 VAL A CG2 1 
ATOM   1780 N  N   . GLU A 1 248 ? 31.71933  -0.22506  -14.59453 1.000 61.14742  ? 248 GLU A N   1 
ATOM   1781 C  CA  . GLU A 1 248 ? 32.11661  1.17694   -14.46665 1.000 62.86565  ? 248 GLU A CA  1 
ATOM   1782 C  C   . GLU A 1 248 ? 31.21508  1.98332   -15.39831 1.000 70.74867  ? 248 GLU A C   1 
ATOM   1783 O  O   . GLU A 1 248 ? 31.43180  2.01168   -16.61366 1.000 66.99090  ? 248 GLU A O   1 
ATOM   1784 C  CB  . GLU A 1 248 ? 33.59307  1.37500   -14.79623 1.000 62.50722  ? 248 GLU A CB  1 
ATOM   1785 C  CG  . GLU A 1 248 ? 34.54158  0.78205   -13.76819 1.000 65.57522  ? 248 GLU A CG  1 
ATOM   1786 C  CD  . GLU A 1 248 ? 35.98532  1.17672   -14.00933 1.000 71.28720  ? 248 GLU A CD  1 
ATOM   1787 O  OE1 . GLU A 1 248 ? 36.22184  2.08470   -14.83127 1.000 78.39773  ? 248 GLU A OE1 1 
ATOM   1788 O  OE2 . GLU A 1 248 ? 36.88406  0.58378   -13.37688 1.000 64.94355  ? 248 GLU A OE2 1 
ATOM   1789 N  N   . VAL A 1 249 ? 30.21033  2.64143   -14.82364 1.000 67.68668  ? 249 VAL A N   1 
ATOM   1790 C  CA  . VAL A 1 249 ? 29.13587  3.27249   -15.58046 1.000 64.08403  ? 249 VAL A CA  1 
ATOM   1791 C  C   . VAL A 1 249 ? 29.41472  4.76026   -15.72963 1.000 63.93615  ? 249 VAL A C   1 
ATOM   1792 O  O   . VAL A 1 249 ? 29.97483  5.40445   -14.83434 1.000 57.32405  ? 249 VAL A O   1 
ATOM   1793 C  CB  . VAL A 1 249 ? 27.77171  3.02977   -14.90088 1.000 55.19387  ? 249 VAL A CB  1 
ATOM   1794 C  CG1 . VAL A 1 249 ? 26.62893  3.53147   -15.77558 1.000 62.64170  ? 249 VAL A CG1 1 
ATOM   1795 C  CG2 . VAL A 1 249 ? 27.59714  1.55628   -14.57466 1.000 67.11678  ? 249 VAL A CG2 1 
ATOM   1796 N  N   . ARG A 1 250 ? 29.02611  5.31023   -16.87833 1.000 60.33319  ? 250 ARG A N   1 
ATOM   1797 C  CA  . ARG A 1 250 ? 29.04051  6.74562   -17.11819 1.000 65.49315  ? 250 ARG A CA  1 
ATOM   1798 C  C   . ARG A 1 250 ? 27.62822  7.29569   -16.97086 1.000 67.40872  ? 250 ARG A C   1 
ATOM   1799 O  O   . ARG A 1 250 ? 26.66849  6.70701   -17.47552 1.000 63.82251  ? 250 ARG A O   1 
ATOM   1800 C  CB  . ARG A 1 250 ? 29.59097  7.06468   -18.50548 1.000 65.25738  ? 250 ARG A CB  1 
ATOM   1801 C  CG  . ARG A 1 250 ? 31.08359  6.82632   -18.64693 1.000 57.95794  ? 250 ARG A CG  1 
ATOM   1802 C  CD  . ARG A 1 250 ? 31.50631  6.80307   -20.10393 1.000 55.32016  ? 250 ARG A CD  1 
ATOM   1803 N  NE  . ARG A 1 250 ? 32.95518  6.75154   -20.25500 1.000 55.01260  ? 250 ARG A NE  1 
ATOM   1804 C  CZ  . ARG A 1 250 ? 33.68566  5.65203   -20.13043 1.000 63.69220  ? 250 ARG A CZ  1 
ATOM   1805 N  NH1 . ARG A 1 250 ? 33.13684  4.48785   -19.82407 1.000 67.24771  ? 250 ARG A NH1 1 
ATOM   1806 N  NH2 . ARG A 1 250 ? 35.00088  5.72284   -20.31436 1.000 57.17197  ? 250 ARG A NH2 1 
ATOM   1807 N  N   . SER A 1 251 ? 27.50484  8.42483   -16.27577 1.000 63.03221  ? 251 SER A N   1 
ATOM   1808 C  CA  . SER A 1 251 ? 26.19538  8.98240   -15.97432 1.000 56.73766  ? 251 SER A CA  1 
ATOM   1809 C  C   . SER A 1 251 ? 26.25856  10.50324  -15.99455 1.000 62.58682  ? 251 SER A C   1 
ATOM   1810 O  O   . SER A 1 251 ? 27.30358  11.10221  -15.72498 1.000 63.76404  ? 251 SER A O   1 
ATOM   1811 C  CB  . SER A 1 251 ? 25.68768  8.48964   -14.61257 1.000 61.78942  ? 251 SER A CB  1 
ATOM   1812 O  OG  . SER A 1 251 ? 24.47162  9.12084   -14.25548 1.000 65.64800  ? 251 SER A OG  1 
ATOM   1813 N  N   . SER A 1 252 ? 25.12022  11.11967  -16.32900 1.000 61.75954  ? 252 SER A N   1 
ATOM   1814 C  CA  . SER A 1 252 ? 24.98996  12.57006  -16.22514 1.000 62.36295  ? 252 SER A CA  1 
ATOM   1815 C  C   . SER A 1 252 ? 24.88820  13.02386  -14.77307 1.000 75.60733  ? 252 SER A C   1 
ATOM   1816 O  O   . SER A 1 252 ? 25.35120  14.11976  -14.43579 1.000 70.25119  ? 252 SER A O   1 
ATOM   1817 C  CB  . SER A 1 252 ? 23.77156  13.04055  -17.01953 1.000 63.14960  ? 252 SER A CB  1 
ATOM   1818 O  OG  . SER A 1 252 ? 22.64066  12.23437  -16.73968 1.000 62.85117  ? 252 SER A OG  1 
ATOM   1819 N  N   . LEU A 1 253 ? 24.24790  12.21761  -13.92212 1.000 72.77164  ? 253 LEU A N   1 
ATOM   1820 C  CA  . LEU A 1 253 ? 24.23168  12.37217  -12.46822 1.000 60.04947  ? 253 LEU A CA  1 
ATOM   1821 C  C   . LEU A 1 253 ? 23.37660  13.53063  -11.96276 1.000 71.82491  ? 253 LEU A C   1 
ATOM   1822 O  O   . LEU A 1 253 ? 23.13884  13.63085  -10.75541 1.000 79.40402  ? 253 LEU A O   1 
ATOM   1823 C  CB  . LEU A 1 253 ? 25.65697  12.53328  -11.92713 1.000 53.55483  ? 253 LEU A CB  1 
ATOM   1824 C  CG  . LEU A 1 253 ? 26.49091  11.26395  -11.74912 1.000 58.06620  ? 253 LEU A CG  1 
ATOM   1825 C  CD1 . LEU A 1 253 ? 27.83743  11.60049  -11.12567 1.000 53.63029  ? 253 LEU A CD1 1 
ATOM   1826 C  CD2 . LEU A 1 253 ? 25.74274  10.24039  -10.90636 1.000 67.08419  ? 253 LEU A CD2 1 
ATOM   1827 N  N   . SER A 1 254 ? 22.87268  14.38387  -12.85113 1.000 71.03837  ? 254 SER A N   1 
ATOM   1828 C  CA  . SER A 1 254 ? 22.09466  15.54251  -12.43335 1.000 62.82351  ? 254 SER A CA  1 
ATOM   1829 C  C   . SER A 1 254 ? 20.82080  15.64489  -13.25955 1.000 71.16232  ? 254 SER A C   1 
ATOM   1830 O  O   . SER A 1 254 ? 20.78484  15.25183  -14.42900 1.000 81.08355  ? 254 SER A O   1 
ATOM   1831 C  CB  . SER A 1 254 ? 22.90015  16.84390  -12.56114 1.000 73.50040  ? 254 SER A CB  1 
ATOM   1832 O  OG  . SER A 1 254 ? 23.12889  17.17296  -13.92010 1.000 83.38295  ? 254 SER A OG  1 
ATOM   1833 N  N   . GLY A 1 255 ? 19.77489  16.19003  -12.63913 1.000 64.61322  ? 255 GLY A N   1 
ATOM   1834 C  CA  . GLY A 1 255 ? 18.49321  16.37040  -13.29129 1.000 69.11496  ? 255 GLY A CA  1 
ATOM   1835 C  C   . GLY A 1 255 ? 17.39032  15.45347  -12.80876 1.000 65.58459  ? 255 GLY A C   1 
ATOM   1836 O  O   . GLY A 1 255 ? 16.29060  15.49039  -13.37484 1.000 68.09115  ? 255 GLY A O   1 
ATOM   1837 N  N   . PHE A 1 256 ? 17.64254  14.63224  -11.79172 1.000 57.40233  ? 256 PHE A N   1 
ATOM   1838 C  CA  . PHE A 1 256 ? 16.60428  13.77012  -11.24093 1.000 56.65015  ? 256 PHE A CA  1 
ATOM   1839 C  C   . PHE A 1 256 ? 15.49354  14.62460  -10.64291 1.000 65.17852  ? 256 PHE A C   1 
ATOM   1840 O  O   . PHE A 1 256 ? 15.75182  15.50222  -9.81560  1.000 70.63142  ? 256 PHE A O   1 
ATOM   1841 C  CB  . PHE A 1 256 ? 17.19606  12.84498  -10.17120 1.000 68.04654  ? 256 PHE A CB  1 
ATOM   1842 C  CG  . PHE A 1 256 ? 18.37427  12.02768  -10.64268 1.000 79.19386  ? 256 PHE A CG  1 
ATOM   1843 C  CD1 . PHE A 1 256 ? 19.61432  12.61359  -10.83911 1.000 82.32802  ? 256 PHE A CD1 1 
ATOM   1844 C  CD2 . PHE A 1 256 ? 18.25081  10.66701  -10.85712 1.000 74.91629  ? 256 PHE A CD2 1 
ATOM   1845 C  CE1 . PHE A 1 256 ? 20.69371  11.86452  -11.26324 1.000 75.05022  ? 256 PHE A CE1 1 
ATOM   1846 C  CE2 . PHE A 1 256 ? 19.33768  9.91686   -11.27579 1.000 69.38882  ? 256 PHE A CE2 1 
ATOM   1847 C  CZ  . PHE A 1 256 ? 20.55624  10.51630  -11.47963 1.000 72.32774  ? 256 PHE A CZ  1 
ATOM   1848 N  N   . PHE A 1 257 ? 14.25541  14.37443  -11.06273 1.000 55.71559  ? 257 PHE A N   1 
ATOM   1849 C  CA  . PHE A 1 257 ? 13.13023  15.20471  -10.65963 1.000 59.97050  ? 257 PHE A CA  1 
ATOM   1850 C  C   . PHE A 1 257 ? 12.09001  14.37947  -9.91310  1.000 63.03662  ? 257 PHE A C   1 
ATOM   1851 O  O   . PHE A 1 257 ? 11.99079  13.16168  -10.09035 1.000 74.48720  ? 257 PHE A O   1 
ATOM   1852 C  CB  . PHE A 1 257 ? 12.48383  15.90450  -11.86898 1.000 67.70669  ? 257 PHE A CB  1 
ATOM   1853 C  CG  . PHE A 1 257 ? 11.64893  15.00058  -12.73384 1.000 64.33710  ? 257 PHE A CG  1 
ATOM   1854 C  CD1 . PHE A 1 257 ? 12.22586  14.26101  -13.75248 1.000 63.64260  ? 257 PHE A CD1 1 
ATOM   1855 C  CD2 . PHE A 1 257 ? 10.27883  14.91355  -12.54481 1.000 67.71922  ? 257 PHE A CD2 1 
ATOM   1856 C  CE1 . PHE A 1 257 ? 11.45291  13.43864  -14.55555 1.000 68.76814  ? 257 PHE A CE1 1 
ATOM   1857 C  CE2 . PHE A 1 257 ? 9.50265   14.09274  -13.34084 1.000 66.05747  ? 257 PHE A CE2 1 
ATOM   1858 C  CZ  . PHE A 1 257 ? 10.08971  13.35491  -14.34803 1.000 71.08579  ? 257 PHE A CZ  1 
ATOM   1859 N  N   . GLU A 1 258 ? 11.32091  15.06250  -9.07080  1.000 72.21038  ? 258 GLU A N   1 
ATOM   1860 C  CA  . GLU A 1 258 ? 10.28076  14.46030  -8.25311  1.000 73.43840  ? 258 GLU A CA  1 
ATOM   1861 C  C   . GLU A 1 258 ? 8.90149   14.87063  -8.75491  1.000 69.72069  ? 258 GLU A C   1 
ATOM   1862 O  O   . GLU A 1 258 ? 8.75528   15.69334  -9.66203  1.000 78.44144  ? 258 GLU A O   1 
ATOM   1863 C  CB  . GLU A 1 258 ? 10.44743  14.85511  -6.78018  1.000 53.96617  ? 258 GLU A CB  1 
ATOM   1864 C  CG  . GLU A 1 258 ? 11.67074  14.25771  -6.10639  1.000 58.45695  ? 258 GLU A CG  1 
ATOM   1865 C  CD  . GLU A 1 258 ? 11.53712  12.76458  -5.86378  1.000 90.48019  ? 258 GLU A CD  1 
ATOM   1866 O  OE1 . GLU A 1 258 ? 10.42530  12.22043  -6.04192  1.000 83.82711  ? 258 GLU A OE1 1 
ATOM   1867 O  OE2 . GLU A 1 258 ? 12.54784  12.13493  -5.48976  1.000 76.44438  ? 258 GLU A OE2 1 
ATOM   1868 N  N   . LEU A 1 259 ? 7.87798   14.26758  -8.14342  1.000 74.77173  ? 259 LEU A N   1 
ATOM   1869 C  CA  . LEU A 1 259 ? 6.50140   14.57559  -8.51502  1.000 82.20885  ? 259 LEU A CA  1 
ATOM   1870 C  C   . LEU A 1 259 ? 6.12838   16.00264  -8.13572  1.000 88.75761  ? 259 LEU A C   1 
ATOM   1871 O  O   . LEU A 1 259 ? 5.37160   16.66415  -8.85673  1.000 80.83284  ? 259 LEU A O   1 
ATOM   1872 C  CB  . LEU A 1 259 ? 5.54660   13.57467  -7.86643  1.000 80.36952  ? 259 LEU A CB  1 
ATOM   1873 C  CG  . LEU A 1 259 ? 5.44877   12.19950  -8.53688  1.000 82.01205  ? 259 LEU A CG  1 
ATOM   1874 C  CD1 . LEU A 1 259 ? 4.72277   11.20414  -7.64400  1.000 78.06025  ? 259 LEU A CD1 1 
ATOM   1875 C  CD2 . LEU A 1 259 ? 4.75072   12.32070  -9.88124  1.000 83.67319  ? 259 LEU A CD2 1 
ATOM   1876 N  N   . ASP A 1 260 ? 6.64142   16.49402  -7.00550  1.000 88.41735  ? 260 ASP A N   1 
ATOM   1877 C  CA  . ASP A 1 260 ? 6.32370   17.85244  -6.58006  1.000 77.66680  ? 260 ASP A CA  1 
ATOM   1878 C  C   . ASP A 1 260 ? 6.96850   18.90529  -7.47464  1.000 84.50522  ? 260 ASP A C   1 
ATOM   1879 O  O   . ASP A 1 260 ? 6.55903   20.07200  -7.43653  1.000 85.75573  ? 260 ASP A O   1 
ATOM   1880 C  CB  . ASP A 1 260 ? 6.73854   18.06094  -5.12037  1.000 78.38325  ? 260 ASP A CB  1 
ATOM   1881 C  CG  . ASP A 1 260 ? 8.24568   18.10331  -4.93054  1.000 80.18054  ? 260 ASP A CG  1 
ATOM   1882 O  OD1 . ASP A 1 260 ? 8.98013   17.52719  -5.76055  1.000 85.07502  ? 260 ASP A OD1 1 
ATOM   1883 O  OD2 . ASP A 1 260 ? 8.69590   18.71208  -3.93744  1.000 96.01280  ? 260 ASP A OD2 1 
ATOM   1884 N  N   . GLY A 1 261 ? 7.95590   18.52092  -8.28051  1.000 74.83434  ? 261 GLY A N   1 
ATOM   1885 C  CA  . GLY A 1 261 ? 8.64395   19.42727  -9.18132  1.000 59.62960  ? 261 GLY A CA  1 
ATOM   1886 C  C   . GLY A 1 261 ? 10.11494  19.61563  -8.87935  1.000 66.88375  ? 261 GLY A C   1 
ATOM   1887 O  O   . GLY A 1 261 ? 10.85584  20.10574  -9.74455  1.000 83.31595  ? 261 GLY A O   1 
ATOM   1888 N  N   . THR A 1 262 ? 10.56370  19.24944  -7.68041  1.000 65.12540  ? 262 THR A N   1 
ATOM   1889 C  CA  . THR A 1 262 ? 11.95169  19.46976  -7.28757  1.000 62.43475  ? 262 THR A CA  1 
ATOM   1890 C  C   . THR A 1 262 ? 12.90900  18.72088  -8.20494  1.000 66.82167  ? 262 THR A C   1 
ATOM   1891 O  O   . THR A 1 262 ? 12.75193  17.51931  -8.43906  1.000 82.95387  ? 262 THR A O   1 
ATOM   1892 C  CB  . THR A 1 262 ? 12.16303  19.02537  -5.83793  1.000 53.39636  ? 262 THR A CB  1 
ATOM   1893 O  OG1 . THR A 1 262 ? 11.25334  19.73790  -4.98541  1.000 60.08500  ? 262 THR A OG1 1 
ATOM   1894 C  CG2 . THR A 1 262 ? 13.59260  19.31010  -5.40785  1.000 53.08990  ? 262 THR A CG2 1 
ATOM   1895 N  N   . VAL A 1 263 ? 13.89809  19.44000  -8.72981  1.000 54.43120  ? 263 VAL A N   1 
ATOM   1896 C  CA  . VAL A 1 263 ? 14.98162  18.85659  -9.51151  1.000 58.90008  ? 263 VAL A CA  1 
ATOM   1897 C  C   . VAL A 1 263 ? 16.24940  18.88545  -8.66936  1.000 60.34745  ? 263 VAL A C   1 
ATOM   1898 O  O   . VAL A 1 263 ? 16.55808  19.89839  -8.03291  1.000 68.09449  ? 263 VAL A O   1 
ATOM   1899 C  CB  . VAL A 1 263 ? 15.18042  19.59637  -10.84913 1.000 55.95624  ? 263 VAL A CB  1 
ATOM   1900 C  CG1 . VAL A 1 263 ? 16.41292  19.07872  -11.57386 1.000 53.70152  ? 263 VAL A CG1 1 
ATOM   1901 C  CG2 . VAL A 1 263 ? 13.94855  19.44702  -11.72788 1.000 64.05217  ? 263 VAL A CG2 1 
ATOM   1902 N  N   . HIS A 1 264 ? 16.98256  17.77413  -8.66791  1.000 59.86798  ? 264 HIS A N   1 
ATOM   1903 C  CA  . HIS A 1 264 ? 18.12529  17.58600  -7.78785  1.000 63.18140  ? 264 HIS A CA  1 
ATOM   1904 C  C   . HIS A 1 264 ? 19.43257  17.91631  -8.50686  1.000 62.95645  ? 264 HIS A C   1 
ATOM   1905 O  O   . HIS A 1 264 ? 19.46268  18.21776  -9.70245  1.000 63.27480  ? 264 HIS A O   1 
ATOM   1906 C  CB  . HIS A 1 264 ? 18.15074  16.15335  -7.25438  1.000 74.79315  ? 264 HIS A CB  1 
ATOM   1907 C  CG  . HIS A 1 264 ? 16.90479  15.75609  -6.52724  1.000 78.31039  ? 264 HIS A CG  1 
ATOM   1908 N  ND1 . HIS A 1 264 ? 16.60905  16.20450  -5.25824  1.000 74.92337  ? 264 HIS A ND1 1 
ATOM   1909 C  CD2 . HIS A 1 264 ? 15.88137  14.94631  -6.88827  1.000 67.32370  ? 264 HIS A CD2 1 
ATOM   1910 C  CE1 . HIS A 1 264 ? 15.45466  15.69251  -4.87076  1.000 73.09920  ? 264 HIS A CE1 1 
ATOM   1911 N  NE2 . HIS A 1 264 ? 14.99250  14.92515  -5.84140  1.000 66.31024  ? 264 HIS A NE2 1 
ATOM   1912 N  N   . ASP A 1 265 ? 20.52911  17.86200  -7.75339  1.000 62.75480  ? 265 ASP A N   1 
ATOM   1913 C  CA  . ASP A 1 265 ? 21.86602  18.13063  -8.25716  1.000 59.21861  ? 265 ASP A CA  1 
ATOM   1914 C  C   . ASP A 1 265 ? 22.59346  16.82092  -8.56917  1.000 71.52520  ? 265 ASP A C   1 
ATOM   1915 O  O   . ASP A 1 265 ? 22.00097  15.73698  -8.57686  1.000 72.09120  ? 265 ASP A O   1 
ATOM   1916 C  CB  . ASP A 1 265 ? 22.64415  18.98143  -7.25092  1.000 53.93557  ? 265 ASP A CB  1 
ATOM   1917 C  CG  . ASP A 1 265 ? 23.13239  18.17952  -6.05990  1.000 75.18956  ? 265 ASP A CG  1 
ATOM   1918 O  OD1 . ASP A 1 265 ? 22.43114  17.23260  -5.64169  1.000 91.08532  ? 265 ASP A OD1 1 
ATOM   1919 O  OD2 . ASP A 1 265 ? 24.22440  18.49635  -5.54243  1.000 79.73279  ? 265 ASP A OD2 1 
ATOM   1920 N  N   . ALA A 1 266 ? 23.89824  16.92272  -8.83925  1.000 70.98012  ? 266 ALA A N   1 
ATOM   1921 C  CA  . ALA A 1 266 ? 24.69101  15.74806  -9.18999  1.000 73.58754  ? 266 ALA A CA  1 
ATOM   1922 C  C   . ALA A 1 266 ? 25.00853  14.87477  -7.97950  1.000 61.95692  ? 266 ALA A C   1 
ATOM   1923 O  O   . ALA A 1 266 ? 24.92344  13.64430  -8.06497  1.000 67.47397  ? 266 ALA A O   1 
ATOM   1924 C  CB  . ALA A 1 266 ? 25.98495  16.17777  -9.88133  1.000 67.77314  ? 266 ALA A CB  1 
ATOM   1925 N  N   . GLU A 1 267 ? 25.38873  15.48395  -6.85249  1.000 58.32066  ? 267 GLU A N   1 
ATOM   1926 C  CA  . GLU A 1 267 ? 25.76034  14.69837  -5.67920  1.000 57.69725  ? 267 GLU A CA  1 
ATOM   1927 C  C   . GLU A 1 267 ? 24.59676  13.85107  -5.18407  1.000 69.99997  ? 267 GLU A C   1 
ATOM   1928 O  O   . GLU A 1 267 ? 24.81151  12.78660  -4.59361  1.000 72.07781  ? 267 GLU A O   1 
ATOM   1929 C  CB  . GLU A 1 267 ? 26.26924  15.62180  -4.57042  1.000 67.12593  ? 267 GLU A CB  1 
ATOM   1930 C  CG  . GLU A 1 267 ? 27.02380  14.91520  -3.45097  1.000 66.57255  ? 267 GLU A CG  1 
ATOM   1931 C  CD  . GLU A 1 267 ? 27.76365  15.88638  -2.54812  1.000 70.71798  ? 267 GLU A CD  1 
ATOM   1932 O  OE1 . GLU A 1 267 ? 27.60400  17.11180  -2.73317  1.000 69.94911  ? 267 GLU A OE1 1 
ATOM   1933 O  OE2 . GLU A 1 267 ? 28.51023  15.42512  -1.65939  1.000 74.80923  ? 267 GLU A OE2 1 
ATOM   1934 N  N   . PHE A 1 268 ? 23.36367  14.30999  -5.40525  1.000 58.68321  ? 268 PHE A N   1 
ATOM   1935 C  CA  . PHE A 1 268 ? 22.19862  13.48422  -5.10841  1.000 58.55395  ? 268 PHE A CA  1 
ATOM   1936 C  C   . PHE A 1 268 ? 22.20976  12.20920  -5.94210  1.000 70.84104  ? 268 PHE A C   1 
ATOM   1937 O  O   . PHE A 1 268 ? 21.96627  11.11206  -5.42676  1.000 74.22675  ? 268 PHE A O   1 
ATOM   1938 C  CB  . PHE A 1 268 ? 20.91876  14.28250  -5.35981  1.000 63.84027  ? 268 PHE A CB  1 
ATOM   1939 C  CG  . PHE A 1 268 ? 19.65795  13.49114  -5.15242  1.000 67.43259  ? 268 PHE A CG  1 
ATOM   1940 C  CD1 . PHE A 1 268 ? 19.14182  13.30754  -3.88111  1.000 68.19834  ? 268 PHE A CD1 1 
ATOM   1941 C  CD2 . PHE A 1 268 ? 18.98391  12.93603  -6.22913  1.000 71.83855  ? 268 PHE A CD2 1 
ATOM   1942 C  CE1 . PHE A 1 268 ? 17.97992  12.58194  -3.68677  1.000 63.63109  ? 268 PHE A CE1 1 
ATOM   1943 C  CE2 . PHE A 1 268 ? 17.82237  12.21021  -6.04069  1.000 64.18608  ? 268 PHE A CE2 1 
ATOM   1944 C  CZ  . PHE A 1 268 ? 17.32014  12.03313  -4.76836  1.000 57.68543  ? 268 PHE A CZ  1 
ATOM   1945 N  N   . GLY A 1 269 ? 22.48647  12.33961  -7.24052  1.000 73.94669  ? 269 GLY A N   1 
ATOM   1946 C  CA  . GLY A 1 269 ? 22.51853  11.16976  -8.10407  1.000 67.39710  ? 269 GLY A CA  1 
ATOM   1947 C  C   . GLY A 1 269 ? 23.61200  10.18887  -7.72804  1.000 68.12837  ? 269 GLY A C   1 
ATOM   1948 O  O   . GLY A 1 269 ? 23.39918  8.97367   -7.72378  1.000 63.41211  ? 269 GLY A O   1 
ATOM   1949 N  N   . LEU A 1 270 ? 24.80549  10.70430  -7.42083  1.000 61.46377  ? 270 LEU A N   1 
ATOM   1950 C  CA  . LEU A 1 270 ? 25.91372  9.82760   -7.05504  1.000 62.30484  ? 270 LEU A CA  1 
ATOM   1951 C  C   . LEU A 1 270 ? 25.59697  9.03306   -5.79467  1.000 71.43264  ? 270 LEU A C   1 
ATOM   1952 O  O   . LEU A 1 270 ? 25.92151  7.84324   -5.70513  1.000 69.91186  ? 270 LEU A O   1 
ATOM   1953 C  CB  . LEU A 1 270 ? 27.19505  10.63983  -6.86843  1.000 56.57260  ? 270 LEU A CB  1 
ATOM   1954 C  CG  . LEU A 1 270 ? 28.46329  9.79540   -6.73196  1.000 49.86228  ? 270 LEU A CG  1 
ATOM   1955 C  CD1 . LEU A 1 270 ? 28.80320  9.12652   -8.05618  1.000 63.30503  ? 270 LEU A CD1 1 
ATOM   1956 C  CD2 . LEU A 1 270 ? 29.63179  10.62635  -6.22916  1.000 52.92272  ? 270 LEU A CD2 1 
ATOM   1957 N  N   . ASN A 1 271 ? 24.96704  9.67351   -4.80659  1.000 75.19885  ? 271 ASN A N   1 
ATOM   1958 C  CA  . ASN A 1 271 ? 24.58934  8.95970   -3.59204  1.000 77.76813  ? 271 ASN A CA  1 
ATOM   1959 C  C   . ASN A 1 271 ? 23.38127  8.05619   -3.80289  1.000 82.06106  ? 271 ASN A C   1 
ATOM   1960 O  O   . ASN A 1 271 ? 23.23171  7.05921   -3.08749  1.000 84.19581  ? 271 ASN A O   1 
ATOM   1961 C  CB  . ASN A 1 271 ? 24.31705  9.94361   -2.45502  1.000 62.82820  ? 271 ASN A CB  1 
ATOM   1962 C  CG  . ASN A 1 271 ? 25.58922  10.49834  -1.85538  1.000 65.75830  ? 271 ASN A CG  1 
ATOM   1963 O  OD1 . ASN A 1 271 ? 26.37506  9.76596   -1.25422  1.000 74.03236  ? 271 ASN A OD1 1 
ATOM   1964 N  ND2 . ASN A 1 271 ? 25.79834  11.79838  -2.01049  1.000 80.46136  ? 271 ASN A ND2 1 
ATOM   1965 N  N   . LEU A 1 272 ? 22.50465  8.38615   -4.75455  1.000 71.03922  ? 272 LEU A N   1 
ATOM   1966 C  CA  . LEU A 1 272 ? 21.42868  7.46218   -5.09786  1.000 65.52615  ? 272 LEU A CA  1 
ATOM   1967 C  C   . LEU A 1 272 ? 21.98867  6.18023   -5.69763  1.000 72.56565  ? 272 LEU A C   1 
ATOM   1968 O  O   . LEU A 1 272 ? 21.50940  5.08223   -5.39187  1.000 79.57133  ? 272 LEU A O   1 
ATOM   1969 C  CB  . LEU A 1 272 ? 20.44067  8.12293   -6.06072  1.000 57.50415  ? 272 LEU A CB  1 
ATOM   1970 C  CG  . LEU A 1 272 ? 19.20575  7.28887   -6.42196  1.000 69.70826  ? 272 LEU A CG  1 
ATOM   1971 C  CD1 . LEU A 1 272 ? 17.93853  8.12931   -6.35866  1.000 66.79870  ? 272 LEU A CD1 1 
ATOM   1972 C  CD2 . LEU A 1 272 ? 19.35627  6.65415   -7.79933  1.000 68.55740  ? 272 LEU A CD2 1 
ATOM   1973 N  N   . TYR A 1 273 ? 22.99946  6.30186   -6.55975  1.000 67.66057  ? 273 TYR A N   1 
ATOM   1974 C  CA  . TYR A 1 273 ? 23.65957  5.11594   -7.09300  1.000 66.84969  ? 273 TYR A CA  1 
ATOM   1975 C  C   . TYR A 1 273 ? 24.45465  4.39747   -6.01277  1.000 66.72498  ? 273 TYR A C   1 
ATOM   1976 O  O   . TYR A 1 273 ? 24.48483  3.16281   -5.97320  1.000 63.16414  ? 273 TYR A O   1 
ATOM   1977 C  CB  . TYR A 1 273 ? 24.56744  5.49869   -8.26001  1.000 64.94962  ? 273 TYR A CB  1 
ATOM   1978 C  CG  . TYR A 1 273 ? 23.81945  5.82213   -9.53025  1.000 68.36048  ? 273 TYR A CG  1 
ATOM   1979 C  CD1 . TYR A 1 273 ? 22.46053  5.55975   -9.64384  1.000 63.31152  ? 273 TYR A CD1 1 
ATOM   1980 C  CD2 . TYR A 1 273 ? 24.47289  6.38211   -10.61849 1.000 67.86535  ? 273 TYR A CD2 1 
ATOM   1981 C  CE1 . TYR A 1 273 ? 21.77322  5.84999   -10.80236 1.000 60.59978  ? 273 TYR A CE1 1 
ATOM   1982 C  CE2 . TYR A 1 273 ? 23.79372  6.67530   -11.78169 1.000 71.18712  ? 273 TYR A CE2 1 
ATOM   1983 C  CZ  . TYR A 1 273 ? 22.44503  6.40660   -11.86720 1.000 67.26717  ? 273 TYR A CZ  1 
ATOM   1984 O  OH  . TYR A 1 273 ? 21.76439  6.69309   -13.02273 1.000 60.71314  ? 273 TYR A OH  1 
ATOM   1985 N  N   . LYS A 1 274 ? 25.10319  5.15493   -5.12738  1.000 67.87890  ? 274 LYS A N   1 
ATOM   1986 C  CA  . LYS A 1 274 ? 25.91707  4.54402   -4.08428  1.000 64.34255  ? 274 LYS A CA  1 
ATOM   1987 C  C   . LYS A 1 274 ? 25.06441  3.76045   -3.09405  1.000 65.48574  ? 274 LYS A C   1 
ATOM   1988 O  O   . LYS A 1 274 ? 25.50158  2.71929   -2.59020  1.000 66.51959  ? 274 LYS A O   1 
ATOM   1989 C  CB  . LYS A 1 274 ? 26.73477  5.61781   -3.36806  1.000 54.06583  ? 274 LYS A CB  1 
ATOM   1990 C  CG  . LYS A 1 274 ? 27.73470  5.07733   -2.36241  1.000 65.54442  ? 274 LYS A CG  1 
ATOM   1991 C  CD  . LYS A 1 274 ? 28.62985  6.18175   -1.82551  1.000 60.89704  ? 274 LYS A CD  1 
ATOM   1992 C  CE  . LYS A 1 274 ? 29.51329  5.67213   -0.70090  1.000 62.14617  ? 274 LYS A CE  1 
ATOM   1993 N  NZ  . LYS A 1 274 ? 28.70806  5.23047   0.46920   1.000 63.95999  ? 274 LYS A NZ  1 
ATOM   1994 N  N   . SER A 1 275 ? 23.85332  4.23823   -2.80187  1.000 64.93039  ? 275 SER A N   1 
ATOM   1995 C  CA  . SER A 1 275 ? 22.96897  3.50619   -1.90068  1.000 71.86450  ? 275 SER A CA  1 
ATOM   1996 C  C   . SER A 1 275 ? 22.52413  2.18456   -2.51833  1.000 68.54079  ? 275 SER A C   1 
ATOM   1997 O  O   . SER A 1 275 ? 22.54209  1.14122   -1.85529  1.000 73.53886  ? 275 SER A O   1 
ATOM   1998 C  CB  . SER A 1 275 ? 21.75970  4.36954   -1.53839  1.000 76.40578  ? 275 SER A CB  1 
ATOM   1999 O  OG  . SER A 1 275 ? 20.94755  4.62237   -2.67073  1.000 84.08132  ? 275 SER A OG  1 
ATOM   2000 N  N   . VAL A 1 276 ? 22.12142  2.21028   -3.79118  1.000 67.70667  ? 276 VAL A N   1 
ATOM   2001 C  CA  . VAL A 1 276 ? 21.67045  0.99170   -4.45898  1.000 69.09111  ? 276 VAL A CA  1 
ATOM   2002 C  C   . VAL A 1 276 ? 22.82076  0.00284   -4.61433  1.000 62.85231  ? 276 VAL A C   1 
ATOM   2003 O  O   . VAL A 1 276 ? 22.63802  -1.21121  -4.46180  1.000 61.14096  ? 276 VAL A O   1 
ATOM   2004 C  CB  . VAL A 1 276 ? 21.02818  1.33545   -5.81559  1.000 70.46975  ? 276 VAL A CB  1 
ATOM   2005 C  CG1 . VAL A 1 276 ? 20.55577  0.07248   -6.51946  1.000 69.26740  ? 276 VAL A CG1 1 
ATOM   2006 C  CG2 . VAL A 1 276 ? 19.87094  2.30336   -5.62279  1.000 63.78038  ? 276 VAL A CG2 1 
ATOM   2007 N  N   . THR A 1 277 ? 24.02082  0.50322   -4.92487  1.000 63.36343  ? 277 THR A N   1 
ATOM   2008 C  CA  . THR A 1 277 ? 25.16877  -0.37750  -5.13065  1.000 64.32357  ? 277 THR A CA  1 
ATOM   2009 C  C   . THR A 1 277 ? 25.50849  -1.16188  -3.86706  1.000 70.07918  ? 277 THR A C   1 
ATOM   2010 O  O   . THR A 1 277 ? 25.77632  -2.36753  -3.93020  1.000 71.08126  ? 277 THR A O   1 
ATOM   2011 C  CB  . THR A 1 277 ? 26.37708  0.43829   -5.59617  1.000 57.29494  ? 277 THR A CB  1 
ATOM   2012 O  OG1 . THR A 1 277 ? 26.09528  1.02829   -6.87181  1.000 47.17587  ? 277 THR A OG1 1 
ATOM   2013 C  CG2 . THR A 1 277 ? 27.61340  -0.44404  -5.71270  1.000 50.84611  ? 277 THR A CG2 1 
ATOM   2014 N  N   . GLU A 1 278 ? 25.49330  -0.49849  -2.70805  1.000 71.68765  ? 278 GLU A N   1 
ATOM   2015 C  CA  . GLU A 1 278 ? 25.88266  -1.15900  -1.46549  1.000 66.20610  ? 278 GLU A CA  1 
ATOM   2016 C  C   . GLU A 1 278 ? 24.80592  -2.11628  -0.96645  1.000 58.24564  ? 278 GLU A C   1 
ATOM   2017 O  O   . GLU A 1 278 ? 25.12416  -3.18730  -0.43577  1.000 55.98011  ? 278 GLU A O   1 
ATOM   2018 C  CB  . GLU A 1 278 ? 26.21161  -0.11250  -0.40333  1.000 68.56193  ? 278 GLU A CB  1 
ATOM   2019 C  CG  . GLU A 1 278 ? 27.45153  0.69282   -0.73214  1.000 71.73818  ? 278 GLU A CG  1 
ATOM   2020 C  CD  . GLU A 1 278 ? 27.70120  1.80503   0.25899   1.000 78.08663  ? 278 GLU A CD  1 
ATOM   2021 O  OE1 . GLU A 1 278 ? 26.78306  2.12027   1.04533   1.000 89.69603  ? 278 GLU A OE1 1 
ATOM   2022 O  OE2 . GLU A 1 278 ? 28.81723  2.36361   0.25156   1.000 82.98885  ? 278 GLU A OE2 1 
ATOM   2023 N  N   . GLU A 1 279 ? 23.53137  -1.74991  -1.12411  1.000 61.85633  ? 279 GLU A N   1 
ATOM   2024 C  CA  . GLU A 1 279 ? 22.45496  -2.69654  -0.85395  1.000 67.52346  ? 279 GLU A CA  1 
ATOM   2025 C  C   . GLU A 1 279 ? 22.58636  -3.93757  -1.72447  1.000 76.31567  ? 279 GLU A C   1 
ATOM   2026 O  O   . GLU A 1 279 ? 22.27543  -5.04805  -1.28062  1.000 80.80341  ? 279 GLU A O   1 
ATOM   2027 C  CB  . GLU A 1 279 ? 21.10177  -2.02075  -1.09205  1.000 74.62039  ? 279 GLU A CB  1 
ATOM   2028 C  CG  . GLU A 1 279 ? 19.89010  -2.92503  -0.91593  1.000 91.58932  ? 279 GLU A CG  1 
ATOM   2029 C  CD  . GLU A 1 279 ? 18.60531  -2.26798  -1.38857  1.000 109.67089 ? 279 GLU A CD  1 
ATOM   2030 O  OE1 . GLU A 1 279 ? 18.63382  -1.60307  -2.44574  1.000 108.07197 ? 279 GLU A OE1 1 
ATOM   2031 O  OE2 . GLU A 1 279 ? 17.57277  -2.40902  -0.69848  1.000 101.47413 ? 279 GLU A OE2 1 
ATOM   2032 N  N   . PHE A 1 280 ? 23.05374  -3.76635  -2.95986  1.000 77.66889  ? 280 PHE A N   1 
ATOM   2033 C  CA  . PHE A 1 280 ? 23.27308  -4.90040  -3.85050  1.000 68.86519  ? 280 PHE A CA  1 
ATOM   2034 C  C   . PHE A 1 280 ? 24.45611  -5.74584  -3.39053  1.000 71.17175  ? 280 PHE A C   1 
ATOM   2035 O  O   . PHE A 1 280 ? 24.36152  -6.97493  -3.33019  1.000 75.69533  ? 280 PHE A O   1 
ATOM   2036 C  CB  . PHE A 1 280 ? 23.49014  -4.38905  -5.27585  1.000 61.44724  ? 280 PHE A CB  1 
ATOM   2037 C  CG  . PHE A 1 280 ? 23.20781  -5.40630  -6.34061  1.000 56.92436  ? 280 PHE A CG  1 
ATOM   2038 C  CD1 . PHE A 1 280 ? 21.90523  -5.67855  -6.72897  1.000 54.05821  ? 280 PHE A CD1 1 
ATOM   2039 C  CD2 . PHE A 1 280 ? 24.24435  -6.06977  -6.97470  1.000 60.94369  ? 280 PHE A CD2 1 
ATOM   2040 C  CE1 . PHE A 1 280 ? 21.64341  -6.60696  -7.71533  1.000 61.80303  ? 280 PHE A CE1 1 
ATOM   2041 C  CE2 . PHE A 1 280 ? 23.98835  -6.99769  -7.96212  1.000 57.40574  ? 280 PHE A CE2 1 
ATOM   2042 C  CZ  . PHE A 1 280 ? 22.68625  -7.26657  -8.33260  1.000 58.85704  ? 280 PHE A CZ  1 
ATOM   2043 N  N   . GLN A 1 281 ? 25.58727  -5.10312  -3.08126  1.000 68.22996  ? 281 GLN A N   1 
ATOM   2044 C  CA  . GLN A 1 281 ? 26.78128  -5.84640  -2.68390  1.000 63.63077  ? 281 GLN A CA  1 
ATOM   2045 C  C   . GLN A 1 281 ? 26.53718  -6.63831  -1.40754  1.000 70.88130  ? 281 GLN A C   1 
ATOM   2046 O  O   . GLN A 1 281 ? 27.05313  -7.75146  -1.24680  1.000 71.96409  ? 281 GLN A O   1 
ATOM   2047 C  CB  . GLN A 1 281 ? 27.96738  -4.89833  -2.49957  1.000 69.03660  ? 281 GLN A CB  1 
ATOM   2048 C  CG  . GLN A 1 281 ? 28.48351  -4.26324  -3.77677  1.000 73.73741  ? 281 GLN A CG  1 
ATOM   2049 C  CD  . GLN A 1 281 ? 29.61590  -3.28226  -3.51826  1.000 83.43745  ? 281 GLN A CD  1 
ATOM   2050 O  OE1 . GLN A 1 281 ? 29.38383  -2.09414  -3.28874  1.000 76.03558  ? 281 GLN A OE1 1 
ATOM   2051 N  NE2 . GLN A 1 281 ? 30.84841  -3.77887  -3.54583  1.000 88.46189  ? 281 GLN A NE2 1 
ATOM   2052 N  N   . ARG A 1 282 ? 25.76380  -6.06949  -0.47951  1.000 75.66610  ? 282 ARG A N   1 
ATOM   2053 C  CA  . ARG A 1 282 ? 25.42525  -6.78223  0.74760   1.000 80.16376  ? 282 ARG A CA  1 
ATOM   2054 C  C   . ARG A 1 282 ? 24.51152  -7.96789  0.46018   1.000 76.49929  ? 282 ARG A C   1 
ATOM   2055 O  O   . ARG A 1 282 ? 24.64466  -9.03101  1.08087   1.000 82.15633  ? 282 ARG A O   1 
ATOM   2056 C  CB  . ARG A 1 282 ? 24.77270  -5.82060  1.74256   1.000 69.88211  ? 282 ARG A CB  1 
ATOM   2057 C  CG  . ARG A 1 282 ? 25.73026  -4.78868  2.32328   1.000 82.97606  ? 282 ARG A CG  1 
ATOM   2058 C  CD  . ARG A 1 282 ? 25.08690  -3.98559  3.45078   1.000 84.36428  ? 282 ARG A CD  1 
ATOM   2059 N  NE  . ARG A 1 282 ? 24.40438  -2.78548  2.97670   1.000 74.44995  ? 282 ARG A NE  1 
ATOM   2060 C  CZ  . ARG A 1 282 ? 23.09282  -2.67859  2.81024   1.000 77.73096  ? 282 ARG A CZ  1 
ATOM   2061 N  NH1 . ARG A 1 282 ? 22.27865  -3.69021  3.06286   1.000 90.29224  ? 282 ARG A NH1 1 
ATOM   2062 N  NH2 . ARG A 1 282 ? 22.58512  -1.52564  2.38364   1.000 73.19637  ? 282 ARG A NH2 1 
ATOM   2063 N  N   . GLU A 1 283 ? 23.58559  -7.80515  -0.48632  1.000 73.79881  ? 283 GLU A N   1 
ATOM   2064 C  CA  . GLU A 1 283 ? 22.63969  -8.86443  -0.81651  1.000 74.50704  ? 283 GLU A CA  1 
ATOM   2065 C  C   . GLU A 1 283 ? 23.29736  -9.98289  -1.61982  1.000 72.49523  ? 283 GLU A C   1 
ATOM   2066 O  O   . GLU A 1 283 ? 22.99565  -11.16200 -1.40729  1.000 70.54768  ? 283 GLU A O   1 
ATOM   2067 C  CB  . GLU A 1 283 ? 21.46036  -8.27095  -1.58277  1.000 67.96767  ? 283 GLU A CB  1 
ATOM   2068 C  CG  . GLU A 1 283 ? 20.28963  -9.21373  -1.79456  1.000 78.37481  ? 283 GLU A CG  1 
ATOM   2069 C  CD  . GLU A 1 283 ? 19.04377  -8.48180  -2.25189  1.000 84.46772  ? 283 GLU A CD  1 
ATOM   2070 O  OE1 . GLU A 1 283 ? 19.03441  -7.23318  -2.19271  1.000 77.11941  ? 283 GLU A OE1 1 
ATOM   2071 O  OE2 . GLU A 1 283 ? 18.07602  -9.15324  -2.66686  1.000 91.24398  ? 283 GLU A OE2 1 
ATOM   2072 N  N   . TYR A 1 284 ? 24.19370  -9.63461  -2.54551  1.000 64.50210  ? 284 TYR A N   1 
ATOM   2073 C  CA  . TYR A 1 284 ? 24.86411  -10.59001 -3.42871  1.000 70.85493  ? 284 TYR A CA  1 
ATOM   2074 C  C   . TYR A 1 284 ? 26.37009  -10.46726 -3.23054  1.000 73.05178  ? 284 TYR A C   1 
ATOM   2075 O  O   . TYR A 1 284 ? 27.02563  -9.63208  -3.87372  1.000 73.15485  ? 284 TYR A O   1 
ATOM   2076 C  CB  . TYR A 1 284 ? 24.47931  -10.34909 -4.88773  1.000 61.15621  ? 284 TYR A CB  1 
ATOM   2077 C  CG  . TYR A 1 284 ? 22.99115  -10.43806 -5.15208  1.000 61.98094  ? 284 TYR A CG  1 
ATOM   2078 C  CD1 . TYR A 1 284 ? 22.36541  -11.66909 -5.29519  1.000 64.33670  ? 284 TYR A CD1 1 
ATOM   2079 C  CD2 . TYR A 1 284 ? 22.21321  -9.29334  -5.26069  1.000 65.98537  ? 284 TYR A CD2 1 
ATOM   2080 C  CE1 . TYR A 1 284 ? 21.00630  -11.75791 -5.53864  1.000 65.34643  ? 284 TYR A CE1 1 
ATOM   2081 C  CE2 . TYR A 1 284 ? 20.85203  -9.37231  -5.50317  1.000 65.58934  ? 284 TYR A CE2 1 
ATOM   2082 C  CZ  . TYR A 1 284 ? 20.25462  -10.60796 -5.64102  1.000 58.68169  ? 284 TYR A CZ  1 
ATOM   2083 O  OH  . TYR A 1 284 ? 18.90219  -10.69674 -5.88256  1.000 67.02967  ? 284 TYR A OH  1 
ATOM   2084 N  N   . PRO A 1 285 ? 26.96260  -11.27481 -2.34470  1.000 75.24195  ? 285 PRO A N   1 
ATOM   2085 C  CA  . PRO A 1 285 ? 28.41299  -11.17710 -2.10685  1.000 67.62043  ? 285 PRO A CA  1 
ATOM   2086 C  C   . PRO A 1 285 ? 29.27044  -11.67700 -3.25884  1.000 74.81010  ? 285 PRO A C   1 
ATOM   2087 O  O   . PRO A 1 285 ? 30.48835  -11.45831 -3.23187  1.000 71.42333  ? 285 PRO A O   1 
ATOM   2088 C  CB  . PRO A 1 285 ? 28.62282  -12.03498 -0.84879  1.000 58.74672  ? 285 PRO A CB  1 
ATOM   2089 C  CG  . PRO A 1 285 ? 27.25977  -12.16090 -0.22855  1.000 67.16506  ? 285 PRO A CG  1 
ATOM   2090 C  CD  . PRO A 1 285 ? 26.30346  -12.16533 -1.37650  1.000 66.99933  ? 285 PRO A CD  1 
ATOM   2091 N  N   . ASP A 1 286 ? 28.69332  -12.34393 -4.26030  1.000 73.47827  ? 286 ASP A N   1 
ATOM   2092 C  CA  . ASP A 1 286 ? 29.48656  -12.76883 -5.40783  1.000 64.93540  ? 286 ASP A CA  1 
ATOM   2093 C  C   . ASP A 1 286 ? 29.87744  -11.59634 -6.29856  1.000 72.61557  ? 286 ASP A C   1 
ATOM   2094 O  O   . ASP A 1 286 ? 30.84438  -11.70366 -7.05788  1.000 71.70236  ? 286 ASP A O   1 
ATOM   2095 C  CB  . ASP A 1 286 ? 28.71958  -13.81583 -6.22095  1.000 67.73741  ? 286 ASP A CB  1 
ATOM   2096 C  CG  . ASP A 1 286 ? 27.39444  -13.29616 -6.74103  1.000 80.72606  ? 286 ASP A CG  1 
ATOM   2097 O  OD1 . ASP A 1 286 ? 27.40688  -12.49900 -7.70073  1.000 84.08118  ? 286 ASP A OD1 1 
ATOM   2098 O  OD2 . ASP A 1 286 ? 26.34138  -13.68667 -6.19536  1.000 75.41178  ? 286 ASP A OD2 1 
ATOM   2099 N  N   . PHE A 1 287 ? 29.14632  -10.48979 -6.21793  1.000 76.22271  ? 287 PHE A N   1 
ATOM   2100 C  CA  . PHE A 1 287 ? 29.41281  -9.31092  -7.02880  1.000 66.73653  ? 287 PHE A CA  1 
ATOM   2101 C  C   . PHE A 1 287 ? 30.64839  -8.58087  -6.51310  1.000 71.60413  ? 287 PHE A C   1 
ATOM   2102 O  O   . PHE A 1 287 ? 30.93692  -8.56977  -5.31565  1.000 79.61431  ? 287 PHE A O   1 
ATOM   2103 C  CB  . PHE A 1 287 ? 28.19396  -8.38665  -6.99949  1.000 73.78955  ? 287 PHE A CB  1 
ATOM   2104 C  CG  . PHE A 1 287 ? 28.11329  -7.43136  -8.15415  1.000 70.57213  ? 287 PHE A CG  1 
ATOM   2105 C  CD1 . PHE A 1 287 ? 27.77295  -7.87824  -9.42064  1.000 69.48753  ? 287 PHE A CD1 1 
ATOM   2106 C  CD2 . PHE A 1 287 ? 28.33700  -6.07949  -7.96342  1.000 63.27067  ? 287 PHE A CD2 1 
ATOM   2107 C  CE1 . PHE A 1 287 ? 27.68129  -6.99506  -10.48017 1.000 69.21779  ? 287 PHE A CE1 1 
ATOM   2108 C  CE2 . PHE A 1 287 ? 28.24736  -5.19191  -9.01719  1.000 76.23594  ? 287 PHE A CE2 1 
ATOM   2109 C  CZ  . PHE A 1 287 ? 27.91887  -5.65015  -10.27767 1.000 69.21292  ? 287 PHE A CZ  1 
ATOM   2110 N  N   . ILE A 1 288 ? 31.39135  -7.97011  -7.43264  1.000 68.88605  ? 288 ILE A N   1 
ATOM   2111 C  CA  . ILE A 1 288 ? 32.57455  -7.21179  -7.03147  1.000 73.79118  ? 288 ILE A CA  1 
ATOM   2112 C  C   . ILE A 1 288 ? 32.20138  -5.78665  -6.64342  1.000 74.79370  ? 288 ILE A C   1 
ATOM   2113 O  O   . ILE A 1 288 ? 32.57303  -5.30928  -5.56597  1.000 79.15681  ? 288 ILE A O   1 
ATOM   2114 C  CB  . ILE A 1 288 ? 33.64132  -7.23481  -8.14463  1.000 65.32496  ? 288 ILE A CB  1 
ATOM   2115 C  CG1 . ILE A 1 288 ? 34.13224  -8.67023  -8.38531  1.000 56.66614  ? 288 ILE A CG1 1 
ATOM   2116 C  CG2 . ILE A 1 288 ? 34.80609  -6.32794  -7.77971  1.000 63.97324  ? 288 ILE A CG2 1 
ATOM   2117 C  CD1 . ILE A 1 288 ? 35.31682  -8.75841  -9.32742  1.000 64.63524  ? 288 ILE A CD1 1 
ATOM   2118 N  N   . GLY A 1 289 ? 31.46317  -5.09553  -7.49615  1.000 80.42056  ? 289 GLY A N   1 
ATOM   2119 C  CA  . GLY A 1 289 ? 30.98394  -3.76619  -7.17962  1.000 70.25935  ? 289 GLY A CA  1 
ATOM   2120 C  C   . GLY A 1 289 ? 30.80187  -2.93370  -8.43499  1.000 72.98756  ? 289 GLY A C   1 
ATOM   2121 O  O   . GLY A 1 289 ? 30.89030  -3.42951  -9.55535  1.000 72.20975  ? 289 GLY A O   1 
ATOM   2122 N  N   . ALA A 1 290 ? 30.54443  -1.64428  -8.21280  1.000 83.56680  ? 290 ALA A N   1 
ATOM   2123 C  CA  . ALA A 1 290 ? 30.31960  -0.68357  -9.28199  1.000 65.55059  ? 290 ALA A CA  1 
ATOM   2124 C  C   . ALA A 1 290 ? 31.02220  0.62508   -8.95002  1.000 61.30558  ? 290 ALA A C   1 
ATOM   2125 O  O   . ALA A 1 290 ? 31.21218  0.96497   -7.77912  1.000 67.80898  ? 290 ALA A O   1 
ATOM   2126 C  CB  . ALA A 1 290 ? 28.82336  -0.43118  -9.50108  1.000 50.92562  ? 290 ALA A CB  1 
ATOM   2127 N  N   . LYS A 1 291 ? 31.40564  1.35629   -9.99744  1.000 59.57435  ? 291 LYS A N   1 
ATOM   2128 C  CA  . LYS A 1 291 ? 32.01309  2.67384   -9.86243  1.000 56.07305  ? 291 LYS A CA  1 
ATOM   2129 C  C   . LYS A 1 291 ? 31.48551  3.57029   -10.97667 1.000 59.90987  ? 291 LYS A C   1 
ATOM   2130 O  O   . LYS A 1 291 ? 31.05167  3.09140   -12.02774 1.000 57.49987  ? 291 LYS A O   1 
ATOM   2131 C  CB  . LYS A 1 291 ? 33.54970  2.59817   -9.89040  1.000 50.35505  ? 291 LYS A CB  1 
ATOM   2132 C  CG  . LYS A 1 291 ? 34.14690  1.72442   -8.79062  1.000 60.47162  ? 291 LYS A CG  1 
ATOM   2133 C  CD  . LYS A 1 291 ? 35.66232  1.79781   -8.75286  1.000 72.62398  ? 291 LYS A CD  1 
ATOM   2134 C  CE  . LYS A 1 291 ? 36.23820  0.83202   -7.72866  1.000 76.49831  ? 291 LYS A CE  1 
ATOM   2135 N  NZ  . LYS A 1 291 ? 35.68366  1.05675   -6.36589  1.000 84.65223  ? 291 LYS A NZ  1 
ATOM   2136 N  N   . ILE A 1 292 ? 31.52575  4.88245   -10.73883 1.000 64.23071  ? 292 ILE A N   1 
ATOM   2137 C  CA  . ILE A 1 292 ? 30.81348  5.84656   -11.56986 1.000 54.80426  ? 292 ILE A CA  1 
ATOM   2138 C  C   . ILE A 1 292 ? 31.79456  6.82025   -12.21178 1.000 56.80025  ? 292 ILE A C   1 
ATOM   2139 O  O   . ILE A 1 292 ? 32.80555  7.20769   -11.61700 1.000 51.16661  ? 292 ILE A O   1 
ATOM   2140 C  CB  . ILE A 1 292 ? 29.74526  6.60792   -10.75339 1.000 39.00778  ? 292 ILE A CB  1 
ATOM   2141 C  CG1 . ILE A 1 292 ? 28.78605  5.62667   -10.08559 1.000 55.79049  ? 292 ILE A CG1 1 
ATOM   2142 C  CG2 . ILE A 1 292 ? 28.95079  7.56035   -11.63520 1.000 47.78571  ? 292 ILE A CG2 1 
ATOM   2143 C  CD1 . ILE A 1 292 ? 27.97952  4.79625   -11.06256 1.000 55.87711  ? 292 ILE A CD1 1 
ATOM   2144 N  N   . ILE A 1 293 ? 31.48146  7.20757   -13.44839 1.000 60.81494  ? 293 ILE A N   1 
ATOM   2145 C  CA  . ILE A 1 293 ? 32.22689  8.20023   -14.21188 1.000 72.95564  ? 293 ILE A CA  1 
ATOM   2146 C  C   . ILE A 1 293 ? 31.24857  9.27939   -14.65416 1.000 75.85560  ? 293 ILE A C   1 
ATOM   2147 O  O   . ILE A 1 293 ? 30.20053  8.97113   -15.23278 1.000 73.43832  ? 293 ILE A O   1 
ATOM   2148 C  CB  . ILE A 1 293 ? 32.92507  7.57787   -15.43681 1.000 63.89429  ? 293 ILE A CB  1 
ATOM   2149 C  CG1 . ILE A 1 293 ? 33.85083  6.43365   -15.01379 1.000 61.11402  ? 293 ILE A CG1 1 
ATOM   2150 C  CG2 . ILE A 1 293 ? 33.69555  8.63886   -16.20689 1.000 73.72263  ? 293 ILE A CG2 1 
ATOM   2151 C  CD1 . ILE A 1 293 ? 34.53953  5.74493   -16.17351 1.000 59.96918  ? 293 ILE A CD1 1 
ATOM   2152 N  N   . LEU A 1 294 ? 31.58133  10.53768  -14.37759 1.000 69.39957  ? 294 LEU A N   1 
ATOM   2153 C  CA  . LEU A 1 294 ? 30.72212  11.64529  -14.77737 1.000 62.85225  ? 294 LEU A CA  1 
ATOM   2154 C  C   . LEU A 1 294 ? 30.89936  11.94496  -16.26209 1.000 56.96976  ? 294 LEU A C   1 
ATOM   2155 O  O   . LEU A 1 294 ? 32.01810  11.92991  -16.78322 1.000 60.44934  ? 294 LEU A O   1 
ATOM   2156 C  CB  . LEU A 1 294 ? 31.03119  12.88854  -13.94241 1.000 57.38235  ? 294 LEU A CB  1 
ATOM   2157 C  CG  . LEU A 1 294 ? 30.14383  14.11218  -14.17753 1.000 54.31882  ? 294 LEU A CG  1 
ATOM   2158 C  CD1 . LEU A 1 294 ? 28.68344  13.74854  -13.98592 1.000 51.93681  ? 294 LEU A CD1 1 
ATOM   2159 C  CD2 . LEU A 1 294 ? 30.53951  15.25031  -13.24936 1.000 53.92475  ? 294 LEU A CD2 1 
ATOM   2160 N  N   . SER A 1 295 ? 29.78562  12.20663  -16.94555 1.000 54.72569  ? 295 SER A N   1 
ATOM   2161 C  CA  . SER A 1 295 ? 29.79090  12.42890  -18.38565 1.000 60.15755  ? 295 SER A CA  1 
ATOM   2162 C  C   . SER A 1 295 ? 29.11806  13.74984  -18.71402 1.000 69.49367  ? 295 SER A C   1 
ATOM   2163 O  O   . SER A 1 295 ? 28.02945  14.04668  -18.20723 1.000 78.16754  ? 295 SER A O   1 
ATOM   2164 C  CB  . SER A 1 295 ? 29.08775  11.29165  -19.13509 1.000 64.58321  ? 295 SER A CB  1 
ATOM   2165 O  OG  . SER A 1 295 ? 27.67901  11.46030  -19.11641 1.000 72.15182  ? 295 SER A OG  1 
ATOM   2166 N  N   . GLY A 1 296 ? 29.77437  14.53355  -19.56024 1.000 65.30079  ? 296 GLY A N   1 
ATOM   2167 C  CA  . GLY A 1 296 ? 29.19653  15.74799  -20.09869 1.000 64.81392  ? 296 GLY A CA  1 
ATOM   2168 C  C   . GLY A 1 296 ? 29.14599  15.66273  -21.61096 1.000 65.84193  ? 296 GLY A C   1 
ATOM   2169 O  O   . GLY A 1 296 ? 29.90698  14.93003  -22.22814 1.000 67.21476  ? 296 GLY A O   1 
ATOM   2170 N  N   . LEU A 1 297 ? 28.23263  16.42384  -22.20076 1.000 64.89321  ? 297 LEU A N   1 
ATOM   2171 C  CA  . LEU A 1 297 ? 27.97561  16.35768  -23.62941 1.000 62.02593  ? 297 LEU A CA  1 
ATOM   2172 C  C   . LEU A 1 297 ? 28.92313  17.28272  -24.38785 1.000 56.84405  ? 297 LEU A C   1 
ATOM   2173 O  O   . LEU A 1 297 ? 29.34133  18.33194  -23.88796 1.000 62.64503  ? 297 LEU A O   1 
ATOM   2174 C  CB  . LEU A 1 297 ? 26.51641  16.70980  -23.91385 1.000 63.20284  ? 297 LEU A CB  1 
ATOM   2175 C  CG  . LEU A 1 297 ? 25.53384  15.76573  -23.21170 1.000 58.95801  ? 297 LEU A CG  1 
ATOM   2176 C  CD1 . LEU A 1 297 ? 24.12689  16.33521  -23.22676 1.000 64.25902  ? 297 LEU A CD1 1 
ATOM   2177 C  CD2 . LEU A 1 297 ? 25.55252  14.36593  -23.82698 1.000 38.94909  ? 297 LEU A CD2 1 
ATOM   2178 N  N   . ARG A 1 298 ? 29.26118  16.87290  -25.61073 1.000 64.04453  ? 298 ARG A N   1 
ATOM   2179 C  CA  . ARG A 1 298 ? 30.28134  17.54306  -26.40600 1.000 57.84918  ? 298 ARG A CA  1 
ATOM   2180 C  C   . ARG A 1 298 ? 29.80750  18.83367  -27.06107 1.000 69.53791  ? 298 ARG A C   1 
ATOM   2181 O  O   . ARG A 1 298 ? 30.63057  19.54012  -27.65548 1.000 76.48094  ? 298 ARG A O   1 
ATOM   2182 C  CB  . ARG A 1 298 ? 30.79483  16.60699  -27.50953 1.000 69.50342  ? 298 ARG A CB  1 
ATOM   2183 C  CG  . ARG A 1 298 ? 31.81668  15.58287  -27.06202 1.000 71.73344  ? 298 ARG A CG  1 
ATOM   2184 C  CD  . ARG A 1 298 ? 32.27401  14.74475  -28.24971 1.000 52.36929  ? 298 ARG A CD  1 
ATOM   2185 N  NE  . ARG A 1 298 ? 33.26528  13.74584  -27.87159 1.000 74.22453  ? 298 ARG A NE  1 
ATOM   2186 C  CZ  . ARG A 1 298 ? 34.57337  13.96141  -27.84875 1.000 76.10235  ? 298 ARG A CZ  1 
ATOM   2187 N  NH1 . ARG A 1 298 ? 35.08571  15.13813  -28.16973 1.000 54.45724  ? 298 ARG A NH1 1 
ATOM   2188 N  NH2 . ARG A 1 298 ? 35.38839  12.97086  -27.49626 1.000 81.35259  ? 298 ARG A NH2 1 
ATOM   2189 N  N   . PHE A 1 299 ? 28.51917  19.15681  -26.99136 1.000 68.57016  ? 299 PHE A N   1 
ATOM   2190 C  CA  . PHE A 1 299 ? 27.98121  20.31799  -27.68862 1.000 61.17401  ? 299 PHE A CA  1 
ATOM   2191 C  C   . PHE A 1 299 ? 27.55824  21.43699  -26.74500 1.000 65.21795  ? 299 PHE A C   1 
ATOM   2192 O  O   . PHE A 1 299 ? 26.87267  22.37249  -27.17409 1.000 84.14003  ? 299 PHE A O   1 
ATOM   2193 C  CB  . PHE A 1 299 ? 26.80139  19.90417  -28.57223 1.000 68.25460  ? 299 PHE A CB  1 
ATOM   2194 C  CG  . PHE A 1 299 ? 25.79665  19.03252  -27.87675 1.000 68.32213  ? 299 PHE A CG  1 
ATOM   2195 C  CD1 . PHE A 1 299 ? 25.92397  17.65299  -27.90251 1.000 60.08631  ? 299 PHE A CD1 1 
ATOM   2196 C  CD2 . PHE A 1 299 ? 24.72360  19.58888  -27.19897 1.000 68.45333  ? 299 PHE A CD2 1 
ATOM   2197 C  CE1 . PHE A 1 299 ? 25.00452  16.84521  -27.26499 1.000 52.36350  ? 299 PHE A CE1 1 
ATOM   2198 C  CE2 . PHE A 1 299 ? 23.79831  18.78473  -26.55913 1.000 72.73996  ? 299 PHE A CE2 1 
ATOM   2199 C  CZ  . PHE A 1 299 ? 23.93961  17.41093  -26.59383 1.000 67.01325  ? 299 PHE A CZ  1 
ATOM   2200 N  N   . LYS A 1 300 ? 27.95241  21.37225  -25.48087 1.000 66.99158  ? 300 LYS A N   1 
ATOM   2201 C  CA  . LYS A 1 300 ? 27.56054  22.36716  -24.49683 1.000 82.14898  ? 300 LYS A CA  1 
ATOM   2202 C  C   . LYS A 1 300 ? 28.69276  23.35961  -24.26594 1.000 86.55602  ? 300 LYS A C   1 
ATOM   2203 O  O   . LYS A 1 300 ? 29.84411  23.12295  -24.63517 1.000 76.83069  ? 300 LYS A O   1 
ATOM   2204 C  CB  . LYS A 1 300 ? 27.14259  21.69146  -23.18854 1.000 75.33848  ? 300 LYS A CB  1 
ATOM   2205 C  CG  . LYS A 1 300 ? 25.94818  20.76847  -23.37570 1.000 79.15715  ? 300 LYS A CG  1 
ATOM   2206 C  CD  . LYS A 1 300 ? 25.26496  20.41241  -22.07037 1.000 77.27363  ? 300 LYS A CD  1 
ATOM   2207 C  CE  . LYS A 1 300 ? 23.89793  19.80624  -22.34807 1.000 80.03835  ? 300 LYS A CE  1 
ATOM   2208 N  NZ  . LYS A 1 300 ? 23.22575  19.30972  -21.11897 1.000 85.58294  ? 300 LYS A NZ  1 
ATOM   2209 N  N   . SER A 1 301 ? 28.34393  24.48781  -23.65451 1.000 71.42256  ? 301 SER A N   1 
ATOM   2210 C  CA  . SER A 1 301 ? 29.27445  25.60352  -23.55491 1.000 61.79057  ? 301 SER A CA  1 
ATOM   2211 C  C   . SER A 1 301 ? 30.52253  25.21706  -22.77019 1.000 64.86228  ? 301 SER A C   1 
ATOM   2212 O  O   . SER A 1 301 ? 30.46496  24.41646  -21.83180 1.000 72.94772  ? 301 SER A O   1 
ATOM   2213 C  CB  . SER A 1 301 ? 28.58556  26.79408  -22.88661 1.000 75.44335  ? 301 SER A CB  1 
ATOM   2214 O  OG  . SER A 1 301 ? 28.21309  26.47515  -21.55805 1.000 86.84769  ? 301 SER A OG  1 
ATOM   2215 N  N   . GLN A 1 302 ? 31.66263  25.78504  -23.17442 1.000 60.89074  ? 302 GLN A N   1 
ATOM   2216 C  CA  . GLN A 1 302 ? 32.90273  25.58283  -22.43155 1.000 55.33858  ? 302 GLN A CA  1 
ATOM   2217 C  C   . GLN A 1 302 ? 32.74748  25.99732  -20.97671 1.000 66.27352  ? 302 GLN A C   1 
ATOM   2218 O  O   . GLN A 1 302 ? 33.43339  25.46257  -20.09687 1.000 58.00346  ? 302 GLN A O   1 
ATOM   2219 C  CB  . GLN A 1 302 ? 34.04089  26.37733  -23.07646 1.000 43.44485  ? 302 GLN A CB  1 
ATOM   2220 C  CG  . GLN A 1 302 ? 34.14345  26.21381  -24.58133 1.000 61.68209  ? 302 GLN A CG  1 
ATOM   2221 C  CD  . GLN A 1 302 ? 35.04982  27.25115  -25.21803 1.000 70.43578  ? 302 GLN A CD  1 
ATOM   2222 O  OE1 . GLN A 1 302 ? 34.59916  28.32607  -25.61357 1.000 91.96670  ? 302 GLN A OE1 1 
ATOM   2223 N  NE2 . GLN A 1 302 ? 36.33314  26.93054  -25.32670 1.000 67.92731  ? 302 GLN A NE2 1 
ATOM   2224 N  N   . GLU A 1 303 ? 31.86396  26.95996  -20.71320 1.000 68.68633  ? 303 GLU A N   1 
ATOM   2225 C  CA  . GLU A 1 303 ? 31.56807  27.36169  -19.34400 1.000 73.61847  ? 303 GLU A CA  1 
ATOM   2226 C  C   . GLU A 1 303 ? 30.99524  26.20112  -18.54114 1.000 70.99199  ? 303 GLU A C   1 
ATOM   2227 O  O   . GLU A 1 303 ? 31.46638  25.90253  -17.43796 1.000 79.91387  ? 303 GLU A O   1 
ATOM   2228 C  CB  . GLU A 1 303 ? 30.59587  28.54199  -19.35984 1.000 90.22272  ? 303 GLU A CB  1 
ATOM   2229 C  CG  . GLU A 1 303 ? 30.21635  29.07793  -17.99225 1.000 100.87024 ? 303 GLU A CG  1 
ATOM   2230 C  CD  . GLU A 1 303 ? 29.34191  30.31403  -18.08707 1.000 108.43559 ? 303 GLU A CD  1 
ATOM   2231 O  OE1 . GLU A 1 303 ? 29.03232  30.73480  -19.22298 1.000 97.02872  ? 303 GLU A OE1 1 
ATOM   2232 O  OE2 . GLU A 1 303 ? 28.96516  30.86254  -17.02974 1.000 112.09375 ? 303 GLU A OE2 1 
ATOM   2233 N  N   . GLU A 1 304 ? 29.97247  25.53294  -19.08063 1.000 63.78942  ? 304 GLU A N   1 
ATOM   2234 C  CA  . GLU A 1 304 ? 29.36923  24.41491  -18.36158 1.000 67.23206  ? 304 GLU A CA  1 
ATOM   2235 C  C   . GLU A 1 304 ? 30.33759  23.24617  -18.23302 1.000 61.26503  ? 304 GLU A C   1 
ATOM   2236 O  O   . GLU A 1 304 ? 30.34456  22.55395  -17.20914 1.000 64.84770  ? 304 GLU A O   1 
ATOM   2237 C  CB  . GLU A 1 304 ? 28.07848  23.96644  -19.04818 1.000 70.75844  ? 304 GLU A CB  1 
ATOM   2238 C  CG  . GLU A 1 304 ? 27.42063  22.77056  -18.36452 1.000 73.38949  ? 304 GLU A CG  1 
ATOM   2239 C  CD  . GLU A 1 304 ? 25.93936  22.64683  -18.66561 1.000 95.75699  ? 304 GLU A CD  1 
ATOM   2240 O  OE1 . GLU A 1 304 ? 25.47068  23.27720  -19.63601 1.000 100.69897 ? 304 GLU A OE1 1 
ATOM   2241 O  OE2 . GLU A 1 304 ? 25.24260  21.92058  -17.92391 1.000 102.90910 ? 304 GLU A OE2 1 
ATOM   2242 N  N   . ILE A 1 305 ? 31.15111  23.00049  -19.26257 1.000 66.32207  ? 305 ILE A N   1 
ATOM   2243 C  CA  . ILE A 1 305 ? 32.08199  21.87641  -19.21021 1.000 62.49320  ? 305 ILE A CA  1 
ATOM   2244 C  C   . ILE A 1 305 ? 33.13056  22.10203  -18.12827 1.000 65.94067  ? 305 ILE A C   1 
ATOM   2245 O  O   . ILE A 1 305 ? 33.53610  21.16438  -17.43355 1.000 68.03663  ? 305 ILE A O   1 
ATOM   2246 C  CB  . ILE A 1 305 ? 32.71857  21.64056  -20.59270 1.000 61.30414  ? 305 ILE A CB  1 
ATOM   2247 C  CG1 . ILE A 1 305 ? 31.62553  21.36408  -21.62781 1.000 59.84105  ? 305 ILE A CG1 1 
ATOM   2248 C  CG2 . ILE A 1 305 ? 33.70259  20.47629  -20.55004 1.000 58.97939  ? 305 ILE A CG2 1 
ATOM   2249 C  CD1 . ILE A 1 305 ? 30.63180  20.30157  -21.20356 1.000 63.74781  ? 305 ILE A CD1 1 
ATOM   2250 N  N   . LEU A 1 306 ? 33.57462  23.34785  -17.95524 1.000 58.55129  ? 306 LEU A N   1 
ATOM   2251 C  CA  . LEU A 1 306 ? 34.41957  23.66321  -16.80882 1.000 64.60208  ? 306 LEU A CA  1 
ATOM   2252 C  C   . LEU A 1 306 ? 33.64759  23.50700  -15.50284 1.000 57.21519  ? 306 LEU A C   1 
ATOM   2253 O  O   . LEU A 1 306 ? 34.19534  23.02417  -14.50456 1.000 55.06490  ? 306 LEU A O   1 
ATOM   2254 C  CB  . LEU A 1 306 ? 34.98768  25.07657  -16.93620 1.000 60.02194  ? 306 LEU A CB  1 
ATOM   2255 C  CG  . LEU A 1 306 ? 35.85146  25.50851  -15.74361 1.000 38.58192  ? 306 LEU A CG  1 
ATOM   2256 C  CD1 . LEU A 1 306 ? 36.98852  24.52361  -15.50943 1.000 62.66573  ? 306 LEU A CD1 1 
ATOM   2257 C  CD2 . LEU A 1 306 ? 36.39216  26.91168  -15.93295 1.000 36.57706  ? 306 LEU A CD2 1 
ATOM   2258 N  N   . ASN A 1 307 ? 32.37253  23.90699  -15.49378 1.000 57.59887  ? 307 ASN A N   1 
ATOM   2259 C  CA  . ASN A 1 307 ? 31.54661  23.75368  -14.29875 1.000 58.21092  ? 307 ASN A CA  1 
ATOM   2260 C  C   . ASN A 1 307 ? 31.43932  22.29164  -13.88583 1.000 61.84579  ? 307 ASN A C   1 
ATOM   2261 O  O   . ASN A 1 307 ? 31.43730  21.97269  -12.68972 1.000 55.92130  ? 307 ASN A O   1 
ATOM   2262 C  CB  . ASN A 1 307 ? 30.15785  24.34443  -14.54735 1.000 60.89024  ? 307 ASN A CB  1 
ATOM   2263 C  CG  . ASN A 1 307 ? 29.20525  24.11265  -13.38713 1.000 94.37950  ? 307 ASN A CG  1 
ATOM   2264 O  OD1 . ASN A 1 307 ? 28.44377  23.14443  -13.37463 1.000 90.21929  ? 307 ASN A OD1 1 
ATOM   2265 N  ND2 . ASN A 1 307 ? 29.23768  25.00965  -12.40857 1.000 107.64376 ? 307 ASN A ND2 1 
ATOM   2266 N  N   . GLU A 1 308 ? 31.34701  21.39009  -14.86497 1.000 65.86596  ? 308 GLU A N   1 
ATOM   2267 C  CA  . GLU A 1 308 ? 31.24987  19.96293  -14.58244 1.000 53.91867  ? 308 GLU A CA  1 
ATOM   2268 C  C   . GLU A 1 308 ? 32.59332  19.37022  -14.16828 1.000 53.66318  ? 308 GLU A C   1 
ATOM   2269 O  O   . GLU A 1 308 ? 32.63574  18.45251  -13.34141 1.000 46.54746  ? 308 GLU A O   1 
ATOM   2270 C  CB  . GLU A 1 308 ? 30.68512  19.24221  -15.80521 1.000 52.83248  ? 308 GLU A CB  1 
ATOM   2271 C  CG  . GLU A 1 308 ? 29.29478  19.73574  -16.19070 1.000 62.18423  ? 308 GLU A CG  1 
ATOM   2272 C  CD  . GLU A 1 308 ? 28.71561  19.01141  -17.38666 1.000 69.13859  ? 308 GLU A CD  1 
ATOM   2273 O  OE1 . GLU A 1 308 ? 29.38287  18.09662  -17.90849 1.000 70.93839  ? 308 GLU A OE1 1 
ATOM   2274 O  OE2 . GLU A 1 308 ? 27.59015  19.36009  -17.80313 1.000 68.46258  ? 308 GLU A OE2 1 
ATOM   2275 N  N   . VAL A 1 309 ? 33.69634  19.86548  -14.73754 1.000 54.17489  ? 309 VAL A N   1 
ATOM   2276 C  CA  . VAL A 1 309 ? 35.01827  19.43574  -14.28352 1.000 55.85642  ? 309 VAL A CA  1 
ATOM   2277 C  C   . VAL A 1 309 ? 35.21697  19.80561  -12.81941 1.000 58.36269  ? 309 VAL A C   1 
ATOM   2278 O  O   . VAL A 1 309 ? 35.82134  19.05178  -12.04671 1.000 57.80003  ? 309 VAL A O   1 
ATOM   2279 C  CB  . VAL A 1 309 ? 36.11994  20.03825  -15.17856 1.000 50.39713  ? 309 VAL A CB  1 
ATOM   2280 C  CG1 . VAL A 1 309 ? 37.49893  19.72712  -14.61232 1.000 44.49636  ? 309 VAL A CG1 1 
ATOM   2281 C  CG2 . VAL A 1 309 ? 36.00492  19.49309  -16.58729 1.000 57.37941  ? 309 VAL A CG2 1 
ATOM   2282 N  N   . LYS A 1 310 ? 34.69624  20.96715  -12.41399 1.000 66.46144  ? 310 LYS A N   1 
ATOM   2283 C  CA  . LYS A 1 310 ? 34.74368  21.36202  -11.01025 1.000 63.30946  ? 310 LYS A CA  1 
ATOM   2284 C  C   . LYS A 1 310 ? 33.93121  20.41192  -10.13682 1.000 62.12110  ? 310 LYS A C   1 
ATOM   2285 O  O   . LYS A 1 310 ? 34.37312  20.03747  -9.04392  1.000 67.20181  ? 310 LYS A O   1 
ATOM   2286 C  CB  . LYS A 1 310 ? 34.23985  22.79617  -10.85693 1.000 67.92922  ? 310 LYS A CB  1 
ATOM   2287 C  CG  . LYS A 1 310 ? 35.16809  23.85478  -11.42641 1.000 51.55489  ? 310 LYS A CG  1 
ATOM   2288 C  CD  . LYS A 1 310 ? 34.48205  25.21138  -11.43746 1.000 63.99912  ? 310 LYS A CD  1 
ATOM   2289 C  CE  . LYS A 1 310 ? 35.41471  26.31796  -11.90201 1.000 65.11460  ? 310 LYS A CE  1 
ATOM   2290 N  NZ  . LYS A 1 310 ? 36.24777  26.85487  -10.79150 1.000 70.79669  ? 310 LYS A NZ  1 
ATOM   2291 N  N   . ILE A 1 311 ? 32.73936  20.01708  -10.59623 1.000 48.92446  ? 311 ILE A N   1 
ATOM   2292 C  CA  . ILE A 1 311 ? 31.93818  19.04879  -9.84944  1.000 51.12468  ? 311 ILE A CA  1 
ATOM   2293 C  C   . ILE A 1 311 ? 32.69476  17.73542  -9.70662  1.000 59.32952  ? 311 ILE A C   1 
ATOM   2294 O  O   . ILE A 1 311 ? 32.70005  17.11681  -8.63597  1.000 60.89434  ? 311 ILE A O   1 
ATOM   2295 C  CB  . ILE A 1 311 ? 30.56836  18.84180  -10.52585 1.000 54.57768  ? 311 ILE A CB  1 
ATOM   2296 C  CG1 . ILE A 1 311 ? 29.69241  20.09265  -10.38315 1.000 60.97350  ? 311 ILE A CG1 1 
ATOM   2297 C  CG2 . ILE A 1 311 ? 29.86636  17.60191  -9.96381  1.000 56.43135  ? 311 ILE A CG2 1 
ATOM   2298 C  CD1 . ILE A 1 311 ? 28.32004  19.95732  -11.02452 1.000 66.67102  ? 311 ILE A CD1 1 
ATOM   2299 N  N   . ALA A 1 312 ? 33.35602  17.29645  -10.78054 1.000 68.84709  ? 312 ALA A N   1 
ATOM   2300 C  CA  . ALA A 1 312 ? 34.11565  16.05249  -10.73467 1.000 54.22682  ? 312 ALA A CA  1 
ATOM   2301 C  C   . ALA A 1 312 ? 35.30137  16.14795  -9.78443  1.000 56.12968  ? 312 ALA A C   1 
ATOM   2302 O  O   . ALA A 1 312 ? 35.65928  15.15200  -9.14608  1.000 70.98303  ? 312 ALA A O   1 
ATOM   2303 C  CB  . ALA A 1 312 ? 34.59041  15.67334  -12.13595 1.000 58.06152  ? 312 ALA A CB  1 
ATOM   2304 N  N   . MET A 1 313 ? 35.93146  17.32105  -9.68722  1.000 52.58521  ? 313 MET A N   1 
ATOM   2305 C  CA  . MET A 1 313 ? 37.05121  17.48154  -8.76504  1.000 57.45298  ? 313 MET A CA  1 
ATOM   2306 C  C   . MET A 1 313 ? 36.60215  17.29979  -7.32077  1.000 76.04892  ? 313 MET A C   1 
ATOM   2307 O  O   . MET A 1 313 ? 37.23621  16.57186  -6.54947  1.000 67.71536  ? 313 MET A O   1 
ATOM   2308 C  CB  . MET A 1 313 ? 37.70219  18.85142  -8.95639  1.000 60.24225  ? 313 MET A CB  1 
ATOM   2309 C  CG  . MET A 1 313 ? 38.48603  18.99854  -10.24652 1.000 60.77873  ? 313 MET A CG  1 
ATOM   2310 S  SD  . MET A 1 313 ? 39.25236  20.62341  -10.38793 1.000 78.25771  ? 313 MET A SD  1 
ATOM   2311 C  CE  . MET A 1 313 ? 40.16457  20.69893  -8.84810  1.000 70.00691  ? 313 MET A CE  1 
ATOM   2312 N  N   . ASP A 1 314 ? 35.50329  17.95362  -6.93601  1.000 75.47483  ? 314 ASP A N   1 
ATOM   2313 C  CA  . ASP A 1 314 ? 35.00167  17.81134  -5.57273  1.000 72.42266  ? 314 ASP A CA  1 
ATOM   2314 C  C   . ASP A 1 314 ? 34.47933  16.40156  -5.32256  1.000 81.35697  ? 314 ASP A C   1 
ATOM   2315 O  O   . ASP A 1 314 ? 34.78050  15.79328  -4.28956  1.000 85.77794  ? 314 ASP A O   1 
ATOM   2316 C  CB  . ASP A 1 314 ? 33.91141  18.84767  -5.29802  1.000 67.81165  ? 314 ASP A CB  1 
ATOM   2317 C  CG  . ASP A 1 314 ? 34.45734  20.25855  -5.20338  1.000 86.48409  ? 314 ASP A CG  1 
ATOM   2318 O  OD1 . ASP A 1 314 ? 35.63682  20.41661  -4.82258  1.000 96.92480  ? 314 ASP A OD1 1 
ATOM   2319 O  OD2 . ASP A 1 314 ? 33.70413  21.20954  -5.50153  1.000 85.86486  ? 314 ASP A OD2 1 
ATOM   2320 N  N   . LEU A 1 315 ? 33.69870  15.86236  -6.26391  1.000 72.07802  ? 315 LEU A N   1 
ATOM   2321 C  CA  . LEU A 1 315 ? 33.13547  14.52736  -6.08329  1.000 65.49950  ? 315 LEU A CA  1 
ATOM   2322 C  C   . LEU A 1 315 ? 34.22963  13.47460  -5.97267  1.000 70.15157  ? 315 LEU A C   1 
ATOM   2323 O  O   . LEU A 1 315 ? 34.08930  12.50090  -5.22406  1.000 76.22326  ? 315 LEU A O   1 
ATOM   2324 C  CB  . LEU A 1 315 ? 32.18342  14.19082  -7.23173  1.000 53.75813  ? 315 LEU A CB  1 
ATOM   2325 C  CG  . LEU A 1 315 ? 30.78254  14.80279  -7.17122  1.000 53.35730  ? 315 LEU A CG  1 
ATOM   2326 C  CD1 . LEU A 1 315 ? 29.89790  14.21570  -8.26034  1.000 58.06582  ? 315 LEU A CD1 1 
ATOM   2327 C  CD2 . LEU A 1 315 ? 30.15843  14.59383  -5.79972  1.000 55.44114  ? 315 LEU A CD2 1 
ATOM   2328 N  N   . HIS A 1 316 ? 35.32324  13.64671  -6.71708  1.000 63.78953  ? 316 HIS A N   1 
ATOM   2329 C  CA  . HIS A 1 316 ? 36.43481  12.70806  -6.61440  1.000 75.62800  ? 316 HIS A CA  1 
ATOM   2330 C  C   . HIS A 1 316 ? 37.05785  12.74573  -5.22377  1.000 78.85672  ? 316 HIS A C   1 
ATOM   2331 O  O   . HIS A 1 316 ? 37.41326  11.70068  -4.66643  1.000 80.76913  ? 316 HIS A O   1 
ATOM   2332 C  CB  . HIS A 1 316 ? 37.48216  13.01447  -7.68342  1.000 66.52599  ? 316 HIS A CB  1 
ATOM   2333 C  CG  . HIS A 1 316 ? 38.47787  11.91591  -7.88293  1.000 57.16270  ? 316 HIS A CG  1 
ATOM   2334 N  ND1 . HIS A 1 316 ? 39.82332  12.15401  -8.06274  1.000 54.87237  ? 316 HIS A ND1 1 
ATOM   2335 C  CD2 . HIS A 1 316 ? 38.32276  10.57188  -7.93678  1.000 57.31096  ? 316 HIS A CD2 1 
ATOM   2336 C  CE1 . HIS A 1 316 ? 40.45522  11.00377  -8.21260  1.000 60.92891  ? 316 HIS A CE1 1 
ATOM   2337 N  NE2 . HIS A 1 316 ? 39.56759  10.02818  -8.14170  1.000 64.37932  ? 316 HIS A NE2 1 
ATOM   2338 N  N   . LYS A 1 317 ? 37.20526  13.94283  -4.64975  1.000 74.00183  ? 317 LYS A N   1 
ATOM   2339 C  CA  . LYS A 1 317 ? 37.73479  14.05356  -3.29364  1.000 76.12342  ? 317 LYS A CA  1 
ATOM   2340 C  C   . LYS A 1 317 ? 36.76756  13.46257  -2.27404  1.000 71.99504  ? 317 LYS A C   1 
ATOM   2341 O  O   . LYS A 1 317 ? 37.15940  12.64562  -1.43258  1.000 72.62253  ? 317 LYS A O   1 
ATOM   2342 C  CB  . LYS A 1 317 ? 38.02892  15.51666  -2.95666  1.000 85.34111  ? 317 LYS A CB  1 
ATOM   2343 C  CG  . LYS A 1 317 ? 38.94030  16.23179  -3.93825  1.000 94.35276  ? 317 LYS A CG  1 
ATOM   2344 C  CD  . LYS A 1 317 ? 38.94593  17.73030  -3.67182  1.000 84.53201  ? 317 LYS A CD  1 
ATOM   2345 C  CE  . LYS A 1 317 ? 39.61334  18.49653  -4.80155  1.000 84.19256  ? 317 LYS A CE  1 
ATOM   2346 N  NZ  . LYS A 1 317 ? 39.55066  19.96752  -4.57876  1.000 91.75874  ? 317 LYS A NZ  1 
ATOM   2347 N  N   . LYS A 1 318 ? 35.49539  13.86545  -2.33638  1.000 67.77800  ? 318 LYS A N   1 
ATOM   2348 C  CA  . LYS A 1 318 ? 34.52392  13.44292  -1.32966  1.000 77.34937  ? 318 LYS A CA  1 
ATOM   2349 C  C   . LYS A 1 318 ? 34.30656  11.93535  -1.35820  1.000 77.89229  ? 318 LYS A C   1 
ATOM   2350 O  O   . LYS A 1 318 ? 34.22620  11.29133  -0.30563  1.000 91.95949  ? 318 LYS A O   1 
ATOM   2351 C  CB  . LYS A 1 318 ? 33.19660  14.17025  -1.54634  1.000 71.02777  ? 318 LYS A CB  1 
ATOM   2352 C  CG  . LYS A 1 318 ? 33.28702  15.68733  -1.52031  1.000 89.02972  ? 318 LYS A CG  1 
ATOM   2353 C  CD  . LYS A 1 318 ? 31.96059  16.31321  -1.92862  1.000 99.02723  ? 318 LYS A CD  1 
ATOM   2354 C  CE  . LYS A 1 318 ? 32.07315  17.82362  -2.06087  1.000 82.43050  ? 318 LYS A CE  1 
ATOM   2355 N  NZ  . LYS A 1 318 ? 30.79293  18.43688  -2.51309  1.000 68.84539  ? 318 LYS A NZ  1 
ATOM   2356 N  N   . TYR A 1 319 ? 34.21415  11.35374  -2.55548  1.000 75.24719  ? 319 TYR A N   1 
ATOM   2357 C  CA  . TYR A 1 319 ? 33.93386  9.93270   -2.74611  1.000 70.33837  ? 319 TYR A CA  1 
ATOM   2358 C  C   . TYR A 1 319 ? 35.10224  9.34923   -3.53257  1.000 74.23454  ? 319 TYR A C   1 
ATOM   2359 O  O   . TYR A 1 319 ? 35.02535  9.18881   -4.76053  1.000 71.83832  ? 319 TYR A O   1 
ATOM   2360 C  CB  . TYR A 1 319 ? 32.59894  9.72283   -3.46097  1.000 61.00401  ? 319 TYR A CB  1 
ATOM   2361 C  CG  . TYR A 1 319 ? 31.45645  10.49489  -2.83058  1.000 67.86846  ? 319 TYR A CG  1 
ATOM   2362 C  CD1 . TYR A 1 319 ? 31.19556  11.80846  -3.20090  1.000 69.94151  ? 319 TYR A CD1 1 
ATOM   2363 C  CD2 . TYR A 1 319 ? 30.64801  9.91633   -1.85990  1.000 75.17071  ? 319 TYR A CD2 1 
ATOM   2364 C  CE1 . TYR A 1 319 ? 30.16263  12.52272  -2.62525  1.000 68.91024  ? 319 TYR A CE1 1 
ATOM   2365 C  CE2 . TYR A 1 319 ? 29.60846  10.62517  -1.27898  1.000 65.12263  ? 319 TYR A CE2 1 
ATOM   2366 C  CZ  . TYR A 1 319 ? 29.37242  11.92733  -1.66730  1.000 64.20324  ? 319 TYR A CZ  1 
ATOM   2367 O  OH  . TYR A 1 319 ? 28.34363  12.63723  -1.09434  1.000 88.69946  ? 319 TYR A OH  1 
ATOM   2368 N  N   . PRO A 1 320 ? 36.20323  9.01574   -2.85308  1.000 73.28804  ? 320 PRO A N   1 
ATOM   2369 C  CA  . PRO A 1 320 ? 37.42217  8.62870   -3.57998  1.000 77.32305  ? 320 PRO A CA  1 
ATOM   2370 C  C   . PRO A 1 320 ? 37.33220  7.27327   -4.25910  1.000 80.65593  ? 320 PRO A C   1 
ATOM   2371 O  O   . PRO A 1 320 ? 38.02614  7.05580   -5.25964  1.000 76.98153  ? 320 PRO A O   1 
ATOM   2372 C  CB  . PRO A 1 320 ? 38.49289  8.64115   -2.48152  1.000 65.77512  ? 320 PRO A CB  1 
ATOM   2373 C  CG  . PRO A 1 320 ? 37.73452  8.31688   -1.23564  1.000 69.04885  ? 320 PRO A CG  1 
ATOM   2374 C  CD  . PRO A 1 320 ? 36.38075  8.95667   -1.39175  1.000 68.21510  ? 320 PRO A CD  1 
ATOM   2375 N  N   . ASP A 1 321 ? 36.50734  6.35559   -3.75519  1.000 78.58427  ? 321 ASP A N   1 
ATOM   2376 C  CA  . ASP A 1 321 ? 36.42569  5.01280   -4.31867  1.000 79.47367  ? 321 ASP A CA  1 
ATOM   2377 C  C   . ASP A 1 321 ? 35.23763  4.80962   -5.24672  1.000 74.93907  ? 321 ASP A C   1 
ATOM   2378 O  O   . ASP A 1 321 ? 35.33991  4.02632   -6.19601  1.000 79.17752  ? 321 ASP A O   1 
ATOM   2379 C  CB  . ASP A 1 321 ? 36.37165  3.96369   -3.20128  1.000 84.14391  ? 321 ASP A CB  1 
ATOM   2380 C  CG  . ASP A 1 321 ? 37.74994  3.58917   -2.68654  1.000 100.74417 ? 321 ASP A CG  1 
ATOM   2381 O  OD1 . ASP A 1 321 ? 38.74145  4.19476   -3.14502  1.000 96.74078  ? 321 ASP A OD1 1 
ATOM   2382 O  OD2 . ASP A 1 321 ? 37.84323  2.68509   -1.82874  1.000 113.66724 ? 321 ASP A OD2 1 
ATOM   2383 N  N   . PHE A 1 322 ? 34.11593  5.48686   -5.00541  1.000 62.79249  ? 322 PHE A N   1 
ATOM   2384 C  CA  . PHE A 1 322 ? 32.95581  5.32060   -5.87010  1.000 52.97285  ? 322 PHE A CA  1 
ATOM   2385 C  C   . PHE A 1 322 ? 33.02111  6.18826   -7.12045  1.000 64.97765  ? 322 PHE A C   1 
ATOM   2386 O  O   . PHE A 1 322 ? 32.35715  5.87004   -8.11359  1.000 66.74762  ? 322 PHE A O   1 
ATOM   2387 C  CB  . PHE A 1 322 ? 31.67518  5.62758   -5.09348  1.000 51.86207  ? 322 PHE A CB  1 
ATOM   2388 C  CG  . PHE A 1 322 ? 30.43305  5.11336   -5.75467  1.000 48.82484  ? 322 PHE A CG  1 
ATOM   2389 C  CD1 . PHE A 1 322 ? 30.33673  3.78353   -6.12953  1.000 53.12492  ? 322 PHE A CD1 1 
ATOM   2390 C  CD2 . PHE A 1 322 ? 29.35913  5.95315   -5.99306  1.000 52.88405  ? 322 PHE A CD2 1 
ATOM   2391 C  CE1 . PHE A 1 322 ? 29.19643  3.30222   -6.73752  1.000 59.37913  ? 322 PHE A CE1 1 
ATOM   2392 C  CE2 . PHE A 1 322 ? 28.21599  5.47871   -6.59992  1.000 63.44552  ? 322 PHE A CE2 1 
ATOM   2393 C  CZ  . PHE A 1 322 ? 28.13322  4.15035   -6.97159  1.000 68.91305  ? 322 PHE A CZ  1 
ATOM   2394 N  N   . PHE A 1 323 ? 33.79612  7.26892   -7.09570  1.000 63.98668  ? 323 PHE A N   1 
ATOM   2395 C  CA  . PHE A 1 323 ? 33.91374  8.18690   -8.21994  1.000 55.85271  ? 323 PHE A CA  1 
ATOM   2396 C  C   . PHE A 1 323 ? 35.28738  8.02500   -8.85502  1.000 61.78297  ? 323 PHE A C   1 
ATOM   2397 O  O   . PHE A 1 323 ? 36.30122  7.97249   -8.14801  1.000 60.87321  ? 323 PHE A O   1 
ATOM   2398 C  CB  . PHE A 1 323 ? 33.69305  9.63163   -7.76641  1.000 48.52948  ? 323 PHE A CB  1 
ATOM   2399 C  CG  . PHE A 1 323 ? 33.43778  10.58796  -8.89300  1.000 55.00937  ? 323 PHE A CG  1 
ATOM   2400 C  CD1 . PHE A 1 323 ? 32.16765  10.72228  -9.42779  1.000 53.87736  ? 323 PHE A CD1 1 
ATOM   2401 C  CD2 . PHE A 1 323 ? 34.46399  11.35956  -9.41143  1.000 64.73688  ? 323 PHE A CD2 1 
ATOM   2402 C  CE1 . PHE A 1 323 ? 31.92552  11.60408  -10.46374 1.000 73.97130  ? 323 PHE A CE1 1 
ATOM   2403 C  CE2 . PHE A 1 323 ? 34.22886  12.24493  -10.44821 1.000 68.03083  ? 323 PHE A CE2 1 
ATOM   2404 C  CZ  . PHE A 1 323 ? 32.95756  12.36711  -10.97441 1.000 70.61554  ? 323 PHE A CZ  1 
ATOM   2405 N  N   . LEU A 1 324 ? 35.31733  7.94765   -10.18513 1.000 62.09712  ? 324 LEU A N   1 
ATOM   2406 C  CA  . LEU A 1 324 ? 36.53782  7.65341   -10.92577 1.000 56.72603  ? 324 LEU A CA  1 
ATOM   2407 C  C   . LEU A 1 324 ? 37.09300  8.86198   -11.66647 1.000 66.72377  ? 324 LEU A C   1 
ATOM   2408 O  O   . LEU A 1 324 ? 38.28326  9.17773   -11.53202 1.000 70.89922  ? 324 LEU A O   1 
ATOM   2409 C  CB  . LEU A 1 324 ? 36.28547  6.52376   -11.92744 1.000 52.76913  ? 324 LEU A CB  1 
ATOM   2410 C  CG  . LEU A 1 324 ? 35.82888  5.21395   -11.29093 1.000 74.10638  ? 324 LEU A CG  1 
ATOM   2411 C  CD1 . LEU A 1 324 ? 35.63422  4.15353   -12.35709 1.000 73.76464  ? 324 LEU A CD1 1 
ATOM   2412 C  CD2 . LEU A 1 324 ? 36.84916  4.77903   -10.25809 1.000 68.63624  ? 324 LEU A CD2 1 
ATOM   2413 N  N   . GLY A 1 325 ? 36.26795  9.54970   -12.46575 1.000 75.64552  ? 325 GLY A N   1 
ATOM   2414 C  CA  . GLY A 1 325 ? 36.74819  10.66610  -13.24523 1.000 55.74575  ? 325 GLY A CA  1 
ATOM   2415 C  C   . GLY A 1 325 ? 35.71570  11.28572  -14.16789 1.000 64.17186  ? 325 GLY A C   1 
ATOM   2416 O  O   . GLY A 1 325 ? 34.51325  11.26167  -13.88655 1.000 65.22706  ? 325 GLY A O   1 
ATOM   2417 N  N   . TYR A 1 326 ? 36.17867  11.85171  -15.28096 1.000 61.82255  ? 326 TYR A N   1 
ATOM   2418 C  CA  . TYR A 1 326 ? 35.31633  12.63521  -16.14893 1.000 62.50492  ? 326 TYR A CA  1 
ATOM   2419 C  C   . TYR A 1 326 ? 35.50471  12.21963  -17.60106 1.000 63.82433  ? 326 TYR A C   1 
ATOM   2420 O  O   . TYR A 1 326 ? 36.57469  11.75095  -18.00165 1.000 58.15107  ? 326 TYR A O   1 
ATOM   2421 C  CB  . TYR A 1 326 ? 35.59624  14.13226  -15.97767 1.000 54.90367  ? 326 TYR A CB  1 
ATOM   2422 C  CG  . TYR A 1 326 ? 34.63201  15.02470  -16.71864 1.000 50.97956  ? 326 TYR A CG  1 
ATOM   2423 C  CD1 . TYR A 1 326 ? 33.31841  15.16443  -16.29060 1.000 52.07502  ? 326 TYR A CD1 1 
ATOM   2424 C  CD2 . TYR A 1 326 ? 35.03745  15.73547  -17.83773 1.000 47.28821  ? 326 TYR A CD2 1 
ATOM   2425 C  CE1 . TYR A 1 326 ? 32.43509  15.98148  -16.96143 1.000 49.50142  ? 326 TYR A CE1 1 
ATOM   2426 C  CE2 . TYR A 1 326 ? 34.16090  16.55571  -18.51440 1.000 55.46359  ? 326 TYR A CE2 1 
ATOM   2427 C  CZ  . TYR A 1 326 ? 32.86120  16.67497  -18.07131 1.000 58.71726  ? 326 TYR A CZ  1 
ATOM   2428 O  OH  . TYR A 1 326 ? 31.98224  17.49121  -18.74172 1.000 70.92210  ? 326 TYR A OH  1 
ATOM   2429 N  N   . ASP A 1 327 ? 34.44144  12.38598  -18.38313 1.000 65.16667  ? 327 ASP A N   1 
ATOM   2430 C  CA  . ASP A 1 327 ? 34.44943  12.03443  -19.79521 1.000 60.55113  ? 327 ASP A CA  1 
ATOM   2431 C  C   . ASP A 1 327 ? 33.44690  12.91796  -20.52422 1.000 68.09051  ? 327 ASP A C   1 
ATOM   2432 O  O   . ASP A 1 327 ? 32.45846  13.36831  -19.93958 1.000 71.41166  ? 327 ASP A O   1 
ATOM   2433 C  CB  . ASP A 1 327 ? 34.11557  10.54883  -19.99423 1.000 70.90103  ? 327 ASP A CB  1 
ATOM   2434 C  CG  . ASP A 1 327 ? 34.22169  10.10379  -21.44288 1.000 74.87309  ? 327 ASP A CG  1 
ATOM   2435 O  OD1 . ASP A 1 327 ? 34.85431  10.80575  -22.25745 1.000 83.63674  ? 327 ASP A OD1 1 
ATOM   2436 O  OD2 . ASP A 1 327 ? 33.66895  9.03503   -21.76631 1.000 67.54891  ? 327 ASP A OD2 1 
ATOM   2437 N  N   . LEU A 1 328 ? 33.71468  13.17175  -21.80179 1.000 63.81193  ? 328 LEU A N   1 
ATOM   2438 C  CA  . LEU A 1 328 ? 32.79412  13.88419  -22.67616 1.000 68.81824  ? 328 LEU A CA  1 
ATOM   2439 C  C   . LEU A 1 328 ? 32.21173  12.91249  -23.69378 1.000 69.34676  ? 328 LEU A C   1 
ATOM   2440 O  O   . LEU A 1 328 ? 32.95552  12.19685  -24.37302 1.000 66.59488  ? 328 LEU A O   1 
ATOM   2441 C  CB  . LEU A 1 328 ? 33.49333  15.04919  -23.38118 1.000 71.89358  ? 328 LEU A CB  1 
ATOM   2442 C  CG  . LEU A 1 328 ? 33.71104  16.28715  -22.51008 1.000 67.31725  ? 328 LEU A CG  1 
ATOM   2443 C  CD1 . LEU A 1 328 ? 34.87838  17.11595  -23.02209 1.000 55.30817  ? 328 LEU A CD1 1 
ATOM   2444 C  CD2 . LEU A 1 328 ? 32.43730  17.11869  -22.46173 1.000 57.27951  ? 328 LEU A CD2 1 
ATOM   2445 N  N   . VAL A 1 329 ? 30.88331  12.89460  -23.79749 1.000 59.49413  ? 329 VAL A N   1 
ATOM   2446 C  CA  . VAL A 1 329 ? 30.16971  11.94697  -24.64708 1.000 64.34745  ? 329 VAL A CA  1 
ATOM   2447 C  C   . VAL A 1 329 ? 29.33807  12.71131  -25.66963 1.000 65.67712  ? 329 VAL A C   1 
ATOM   2448 O  O   . VAL A 1 329 ? 29.38285  13.94557  -25.72646 1.000 49.87034  ? 329 VAL A O   1 
ATOM   2449 C  CB  . VAL A 1 329 ? 29.28604  11.00008  -23.81275 1.000 56.18057  ? 329 VAL A CB  1 
ATOM   2450 C  CG1 . VAL A 1 329 ? 30.10956  10.32112  -22.72908 1.000 65.11510  ? 329 VAL A CG1 1 
ATOM   2451 C  CG2 . VAL A 1 329 ? 28.11177  11.75559  -23.20805 1.000 57.42083  ? 329 VAL A CG2 1 
ATOM   2452 N  N   . GLY A 1 330 ? 28.57718  11.98436  -26.47987 1.000 71.08491  ? 330 GLY A N   1 
ATOM   2453 C  CA  . GLY A 1 330 ? 27.87216  12.55307  -27.60694 1.000 60.88918  ? 330 GLY A CA  1 
ATOM   2454 C  C   . GLY A 1 330 ? 28.62886  12.33555  -28.90542 1.000 65.15913  ? 330 GLY A C   1 
ATOM   2455 O  O   . GLY A 1 330 ? 29.81526  12.00573  -28.92248 1.000 72.83142  ? 330 GLY A O   1 
ATOM   2456 N  N   . GLN A 1 331 ? 27.92014  12.52010  -30.01720 1.000 54.31941  ? 331 GLN A N   1 
ATOM   2457 C  CA  . GLN A 1 331 ? 28.49136  12.21993  -31.32516 1.000 55.27294  ? 331 GLN A CA  1 
ATOM   2458 C  C   . GLN A 1 331 ? 29.77657  13.00988  -31.53936 1.000 56.06933  ? 331 GLN A C   1 
ATOM   2459 O  O   . GLN A 1 331 ? 29.82285  14.22206  -31.31377 1.000 63.00002  ? 331 GLN A O   1 
ATOM   2460 C  CB  . GLN A 1 331 ? 27.48470  12.52576  -32.43143 1.000 59.42427  ? 331 GLN A CB  1 
ATOM   2461 C  CG  . GLN A 1 331 ? 27.77687  11.79294  -33.72660 1.000 64.32346  ? 331 GLN A CG  1 
ATOM   2462 C  CD  . GLN A 1 331 ? 26.82791  12.17561  -34.84200 1.000 62.59504  ? 331 GLN A CD  1 
ATOM   2463 O  OE1 . GLN A 1 331 ? 25.89680  12.95475  -34.64092 1.000 57.84491  ? 331 GLN A OE1 1 
ATOM   2464 N  NE2 . GLN A 1 331 ? 27.06183  11.63037  -36.02975 1.000 68.25340  ? 331 GLN A NE2 1 
ATOM   2465 N  N   . GLU A 1 332 ? 30.82441  12.31262  -31.97483 1.000 51.26530  ? 332 GLU A N   1 
ATOM   2466 C  CA  . GLU A 1 332 ? 32.16563  12.88100  -31.98560 1.000 58.29125  ? 332 GLU A CA  1 
ATOM   2467 C  C   . GLU A 1 332 ? 32.47837  13.65977  -33.25484 1.000 69.41624  ? 332 GLU A C   1 
ATOM   2468 O  O   . GLU A 1 332 ? 33.27856  14.60020  -33.21055 1.000 68.37150  ? 332 GLU A O   1 
ATOM   2469 C  CB  . GLU A 1 332 ? 33.19887  11.76693  -31.79208 1.000 48.31263  ? 332 GLU A CB  1 
ATOM   2470 C  CG  . GLU A 1 332 ? 34.51842  12.22706  -31.20161 1.000 66.90927  ? 332 GLU A CG  1 
ATOM   2471 C  CD  . GLU A 1 332 ? 35.35908  11.07206  -30.69134 1.000 76.05752  ? 332 GLU A CD  1 
ATOM   2472 O  OE1 . GLU A 1 332 ? 34.78704  9.99783   -30.40745 1.000 70.84610  ? 332 GLU A OE1 1 
ATOM   2473 O  OE2 . GLU A 1 332 ? 36.59093  11.23956  -30.57357 1.000 70.48441  ? 332 GLU A OE2 1 
ATOM   2474 N  N   . ASP A 1 333 ? 31.86454  13.29437  -34.38730 1.000 64.31349  ? 333 ASP A N   1 
ATOM   2475 C  CA  . ASP A 1 333 ? 32.17547  13.98524  -35.63944 1.000 64.94565  ? 333 ASP A CA  1 
ATOM   2476 C  C   . ASP A 1 333 ? 31.59048  15.39202  -35.68883 1.000 57.75894  ? 333 ASP A C   1 
ATOM   2477 O  O   . ASP A 1 333 ? 32.36074  16.35700  -35.85191 1.000 55.77320  ? 333 ASP A O   1 
ATOM   2478 C  CB  . ASP A 1 333 ? 31.73263  13.13408  -36.83326 1.000 83.70073  ? 333 ASP A CB  1 
ATOM   2479 C  CG  . ASP A 1 333 ? 32.63895  11.94033  -37.07186 1.000 79.43994  ? 333 ASP A CG  1 
ATOM   2480 O  OD1 . ASP A 1 333 ? 33.57942  11.73365  -36.27838 1.000 71.66310  ? 333 ASP A OD1 1 
ATOM   2481 O  OD2 . ASP A 1 333 ? 32.41107  11.20918  -38.06114 1.000 77.44507  ? 333 ASP A OD2 1 
ATOM   2482 N  N   . PRO A 1 334 ? 30.26936  15.59543  -35.56963 1.000 53.56532  ? 334 PRO A N   1 
ATOM   2483 C  CA  . PRO A 1 334 ? 29.72565  16.93688  -35.80792 1.000 54.97757  ? 334 PRO A CA  1 
ATOM   2484 C  C   . PRO A 1 334 ? 29.79661  17.87175  -34.61163 1.000 59.33517  ? 334 PRO A C   1 
ATOM   2485 O  O   . PRO A 1 334 ? 29.45457  19.05344  -34.75486 1.000 67.73387  ? 334 PRO A O   1 
ATOM   2486 C  CB  . PRO A 1 334 ? 28.27679  16.65394  -36.20252 1.000 46.16252  ? 334 PRO A CB  1 
ATOM   2487 C  CG  . PRO A 1 334 ? 27.92709  15.48748  -35.36429 1.000 47.76230  ? 334 PRO A CG  1 
ATOM   2488 C  CD  . PRO A 1 334 ? 29.19442  14.66178  -35.20358 1.000 53.05808  ? 334 PRO A CD  1 
ATOM   2489 N  N   . ASN A 1 335 ? 30.20732  17.39244  -33.44732 1.000 58.46985  ? 335 ASN A N   1 
ATOM   2490 C  CA  . ASN A 1 335 ? 30.27520  18.21647  -32.25469 1.000 54.89620  ? 335 ASN A CA  1 
ATOM   2491 C  C   . ASN A 1 335 ? 31.72226  18.62175  -31.98453 1.000 55.56178  ? 335 ASN A C   1 
ATOM   2492 O  O   . ASN A 1 335 ? 32.61943  18.39306  -32.80165 1.000 56.92421  ? 335 ASN A O   1 
ATOM   2493 C  CB  . ASN A 1 335 ? 29.64160  17.47785  -31.07399 1.000 54.35211  ? 335 ASN A CB  1 
ATOM   2494 C  CG  . ASN A 1 335 ? 28.16745  17.18137  -31.29731 1.000 56.13580  ? 335 ASN A CG  1 
ATOM   2495 O  OD1 . ASN A 1 335 ? 27.51590  17.79570  -32.14510 1.000 53.70787  ? 335 ASN A OD1 1 
ATOM   2496 N  ND2 . ASN A 1 335 ? 27.63271  16.24143  -30.52784 1.000 67.37911  ? 335 ASN A ND2 1 
ATOM   2497 N  N   . PHE A 1 336 ? 31.95919  19.22422  -30.82191 1.000 53.42208  ? 336 PHE A N   1 
ATOM   2498 C  CA  . PHE A 1 336 ? 33.24829  19.83434  -30.53733 1.000 58.76361  ? 336 PHE A CA  1 
ATOM   2499 C  C   . PHE A 1 336 ? 34.32411  18.77033  -30.33484 1.000 48.39811  ? 336 PHE A C   1 
ATOM   2500 O  O   . PHE A 1 336 ? 34.05732  17.56562  -30.28971 1.000 67.35183  ? 336 PHE A O   1 
ATOM   2501 C  CB  . PHE A 1 336 ? 33.15554  20.72889  -29.30235 1.000 65.14742  ? 336 PHE A CB  1 
ATOM   2502 C  CG  . PHE A 1 336 ? 32.29336  21.94481  -29.49529 1.000 68.22982  ? 336 PHE A CG  1 
ATOM   2503 C  CD1 . PHE A 1 336 ? 32.41548  22.72741  -30.63103 1.000 60.65897  ? 336 PHE A CD1 1 
ATOM   2504 C  CD2 . PHE A 1 336 ? 31.36364  22.30701  -28.53540 1.000 71.14420  ? 336 PHE A CD2 1 
ATOM   2505 C  CE1 . PHE A 1 336 ? 31.61970  23.84652  -30.80715 1.000 49.83057  ? 336 PHE A CE1 1 
ATOM   2506 C  CE2 . PHE A 1 336 ? 30.56569  23.42202  -28.70453 1.000 64.19728  ? 336 PHE A CE2 1 
ATOM   2507 C  CZ  . PHE A 1 336 ? 30.69361  24.19400  -29.84143 1.000 45.98972  ? 336 PHE A CZ  1 
ATOM   2508 N  N   . SER A 1 337 ? 35.55931  19.23943  -30.21508 1.000 48.81599  ? 337 SER A N   1 
ATOM   2509 C  CA  . SER A 1 337 ? 36.73259  18.40402  -30.01556 1.000 52.16299  ? 337 SER A CA  1 
ATOM   2510 C  C   . SER A 1 337 ? 37.22976  18.54639  -28.57987 1.000 63.38752  ? 337 SER A C   1 
ATOM   2511 O  O   . SER A 1 337 ? 36.71772  19.34865  -27.79407 1.000 67.16159  ? 337 SER A O   1 
ATOM   2512 C  CB  . SER A 1 337 ? 37.82649  18.77155  -31.02005 1.000 60.15578  ? 337 SER A CB  1 
ATOM   2513 O  OG  . SER A 1 337 ? 38.16467  20.14632  -30.93180 1.000 68.23850  ? 337 SER A OG  1 
ATOM   2514 N  N   . LEU A 1 338 ? 38.24633  17.74998  -28.23760 1.000 67.31050  ? 338 LEU A N   1 
ATOM   2515 C  CA  . LEU A 1 338 ? 38.85063  17.84715  -26.91499 1.000 64.77010  ? 338 LEU A CA  1 
ATOM   2516 C  C   . LEU A 1 338 ? 39.77624  19.04770  -26.78522 1.000 67.11053  ? 338 LEU A C   1 
ATOM   2517 O  O   . LEU A 1 338 ? 40.05562  19.47798  -25.66093 1.000 61.58958  ? 338 LEU A O   1 
ATOM   2518 C  CB  . LEU A 1 338 ? 39.62689  16.57072  -26.58150 1.000 68.85957  ? 338 LEU A CB  1 
ATOM   2519 C  CG  . LEU A 1 338 ? 38.82420  15.27468  -26.42817 1.000 60.82918  ? 338 LEU A CG  1 
ATOM   2520 C  CD1 . LEU A 1 338 ? 39.71031  14.15527  -25.88862 1.000 58.44109  ? 338 LEU A CD1 1 
ATOM   2521 C  CD2 . LEU A 1 338 ? 37.60192  15.48265  -25.54533 1.000 60.67397  ? 338 LEU A CD2 1 
ATOM   2522 N  N   . LEU A 1 339 ? 40.26142  19.59107  -27.90449 1.000 79.75164  ? 339 LEU A N   1 
ATOM   2523 C  CA  . LEU A 1 339 ? 41.07794  20.79855  -27.85982 1.000 67.94232  ? 339 LEU A CA  1 
ATOM   2524 C  C   . LEU A 1 339 ? 40.22849  22.03450  -27.60549 1.000 66.78304  ? 339 LEU A C   1 
ATOM   2525 O  O   . LEU A 1 339 ? 40.69291  22.98510  -26.96625 1.000 71.34657  ? 339 LEU A O   1 
ATOM   2526 C  CB  . LEU A 1 339 ? 41.85644  20.95309  -29.16740 1.000 74.65785  ? 339 LEU A CB  1 
ATOM   2527 C  CG  . LEU A 1 339 ? 42.97691  21.99440  -29.21407 1.000 61.47100  ? 339 LEU A CG  1 
ATOM   2528 C  CD1 . LEU A 1 339 ? 44.18568  21.51926  -28.42099 1.000 74.28225  ? 339 LEU A CD1 1 
ATOM   2529 C  CD2 . LEU A 1 339 ? 43.36090  22.30954  -30.65292 1.000 48.27761  ? 339 LEU A CD2 1 
ATOM   2530 N  N   . HIS A 1 340 ? 38.98307  22.02538  -28.08447 1.000 62.72678  ? 340 HIS A N   1 
ATOM   2531 C  CA  . HIS A 1 340 ? 38.03640  23.10568  -27.84265 1.000 65.60215  ? 340 HIS A CA  1 
ATOM   2532 C  C   . HIS A 1 340 ? 37.69265  23.25349  -26.36558 1.000 74.98125  ? 340 HIS A C   1 
ATOM   2533 O  O   . HIS A 1 340 ? 37.07923  24.25542  -25.98450 1.000 80.43179  ? 340 HIS A O   1 
ATOM   2534 C  CB  . HIS A 1 340 ? 36.78037  22.85060  -28.68283 1.000 61.99736  ? 340 HIS A CB  1 
ATOM   2535 C  CG  . HIS A 1 340 ? 35.71230  23.88733  -28.52946 1.000 62.31692  ? 340 HIS A CG  1 
ATOM   2536 N  ND1 . HIS A 1 340 ? 34.58993  23.68580  -27.75600 1.000 68.28482  ? 340 HIS A ND1 1 
ATOM   2537 C  CD2 . HIS A 1 340 ? 35.58428  25.12542  -29.06248 1.000 71.32005  ? 340 HIS A CD2 1 
ATOM   2538 C  CE1 . HIS A 1 340 ? 33.81960  24.75714  -27.81314 1.000 68.60588  ? 340 HIS A CE1 1 
ATOM   2539 N  NE2 . HIS A 1 340 ? 34.40019  25.64585  -28.59881 1.000 76.09645  ? 340 HIS A NE2 1 
ATOM   2540 N  N   . TYR A 1 341 ? 38.08308  22.29069  -25.52774 1.000 68.75515  ? 341 TYR A N   1 
ATOM   2541 C  CA  . TYR A 1 341 ? 37.81103  22.32324  -24.09529 1.000 51.77826  ? 341 TYR A CA  1 
ATOM   2542 C  C   . TYR A 1 341 ? 39.08845  22.31514  -23.26171 1.000 57.15433  ? 341 TYR A C   1 
ATOM   2543 O  O   . TYR A 1 341 ? 39.05662  21.90477  -22.09755 1.000 67.21696  ? 341 TYR A O   1 
ATOM   2544 C  CB  . TYR A 1 341 ? 36.93462  21.13771  -23.69414 1.000 62.98826  ? 341 TYR A CB  1 
ATOM   2545 C  CG  . TYR A 1 341 ? 35.50958  21.20045  -24.18538 1.000 57.38576  ? 341 TYR A CG  1 
ATOM   2546 C  CD1 . TYR A 1 341 ? 34.72688  22.32357  -23.96709 1.000 54.18032  ? 341 TYR A CD1 1 
ATOM   2547 C  CD2 . TYR A 1 341 ? 34.94441  20.12781  -24.86013 1.000 71.25277  ? 341 TYR A CD2 1 
ATOM   2548 C  CE1 . TYR A 1 341 ? 33.42288  22.37709  -24.40871 1.000 60.23172  ? 341 TYR A CE1 1 
ATOM   2549 C  CE2 . TYR A 1 341 ? 33.64170  20.17136  -25.30505 1.000 66.27756  ? 341 TYR A CE2 1 
ATOM   2550 C  CZ  . TYR A 1 341 ? 32.88580  21.29842  -25.07629 1.000 57.10456  ? 341 TYR A CZ  1 
ATOM   2551 O  OH  . TYR A 1 341 ? 31.58733  21.34973  -25.51813 1.000 62.04520  ? 341 TYR A OH  1 
ATOM   2552 N  N   . LEU A 1 342 ? 40.21375  22.75528  -23.83017 1.000 57.96378  ? 342 LEU A N   1 
ATOM   2553 C  CA  . LEU A 1 342 ? 41.49274  22.60579  -23.14107 1.000 64.40044  ? 342 LEU A CA  1 
ATOM   2554 C  C   . LEU A 1 342 ? 41.55073  23.44305  -21.86725 1.000 66.77383  ? 342 LEU A C   1 
ATOM   2555 O  O   . LEU A 1 342 ? 42.11399  23.00150  -20.85807 1.000 65.36852  ? 342 LEU A O   1 
ATOM   2556 C  CB  . LEU A 1 342 ? 42.64382  22.96938  -24.07644 1.000 57.20083  ? 342 LEU A CB  1 
ATOM   2557 C  CG  . LEU A 1 342 ? 44.03900  22.78350  -23.47964 1.000 54.06225  ? 342 LEU A CG  1 
ATOM   2558 C  CD1 . LEU A 1 342 ? 44.25932  21.32951  -23.09915 1.000 72.47731  ? 342 LEU A CD1 1 
ATOM   2559 C  CD2 . LEU A 1 342 ? 45.10154  23.25411  -24.45166 1.000 54.00543  ? 342 LEU A CD2 1 
ATOM   2560 N  N   . ASP A 1 343 ? 40.98488  24.65453  -21.89214 1.000 81.28868  ? 343 ASP A N   1 
ATOM   2561 C  CA  . ASP A 1 343 ? 40.98041  25.48879  -20.69207 1.000 70.68676  ? 343 ASP A CA  1 
ATOM   2562 C  C   . ASP A 1 343 ? 40.29998  24.79235  -19.52018 1.000 71.42326  ? 343 ASP A C   1 
ATOM   2563 O  O   . ASP A 1 343 ? 40.70229  24.98420  -18.36763 1.000 76.81832  ? 343 ASP A O   1 
ATOM   2564 C  CB  . ASP A 1 343 ? 40.29287  26.82284  -20.98267 1.000 79.67710  ? 343 ASP A CB  1 
ATOM   2565 C  CG  . ASP A 1 343 ? 40.94179  27.57639  -22.12310 1.000 97.48729  ? 343 ASP A CG  1 
ATOM   2566 O  OD1 . ASP A 1 343 ? 42.19144  27.57640  -22.20710 1.000 98.65422  ? 343 ASP A OD1 1 
ATOM   2567 O  OD2 . ASP A 1 343 ? 40.20337  28.16495  -22.93997 1.000 91.48771  ? 343 ASP A OD2 1 
ATOM   2568 N  N   . ALA A 1 344 ? 39.27408  23.98406  -19.79095 1.000 72.67882  ? 344 ALA A N   1 
ATOM   2569 C  CA  . ALA A 1 344 ? 38.59876  23.24428  -18.73012 1.000 60.41806  ? 344 ALA A CA  1 
ATOM   2570 C  C   . ALA A 1 344 ? 39.36074  21.97892  -18.35436 1.000 64.28830  ? 344 ALA A C   1 
ATOM   2571 O  O   . ALA A 1 344 ? 39.55174  21.69119  -17.16869 1.000 71.35667  ? 344 ALA A O   1 
ATOM   2572 C  CB  . ALA A 1 344 ? 37.17104  22.89682  -19.15563 1.000 54.11046  ? 344 ALA A CB  1 
ATOM   2573 N  N   . LEU A 1 345 ? 39.79495  21.20544  -19.35163 1.000 68.37644  ? 345 LEU A N   1 
ATOM   2574 C  CA  . LEU A 1 345 ? 40.42811  19.91847  -19.08740 1.000 74.02135  ? 345 LEU A CA  1 
ATOM   2575 C  C   . LEU A 1 345 ? 41.85539  20.04912  -18.56795 1.000 74.66271  ? 345 LEU A C   1 
ATOM   2576 O  O   . LEU A 1 345 ? 42.40477  19.06074  -18.06874 1.000 69.04598  ? 345 LEU A O   1 
ATOM   2577 C  CB  . LEU A 1 345 ? 40.39794  19.05998  -20.35371 1.000 66.47130  ? 345 LEU A CB  1 
ATOM   2578 C  CG  . LEU A 1 345 ? 38.98810  18.78845  -20.89007 1.000 63.11587  ? 345 LEU A CG  1 
ATOM   2579 C  CD1 . LEU A 1 345 ? 39.02784  18.08660  -22.24004 1.000 61.14432  ? 345 LEU A CD1 1 
ATOM   2580 C  CD2 . LEU A 1 345 ? 38.18121  17.97853  -19.88484 1.000 61.20789  ? 345 LEU A CD2 1 
ATOM   2581 N  N   . LEU A 1 346 ? 42.46784  21.22840  -18.67663 1.000 69.04518  ? 346 LEU A N   1 
ATOM   2582 C  CA  . LEU A 1 346 ? 43.75042  21.50279  -18.04236 1.000 70.27963  ? 346 LEU A CA  1 
ATOM   2583 C  C   . LEU A 1 346 ? 43.60692  22.21195  -16.70324 1.000 74.98613  ? 346 LEU A C   1 
ATOM   2584 O  O   . LEU A 1 346 ? 44.59841  22.33813  -15.97732 1.000 71.64125  ? 346 LEU A O   1 
ATOM   2585 C  CB  . LEU A 1 346 ? 44.63749  22.35015  -18.96304 1.000 50.69743  ? 346 LEU A CB  1 
ATOM   2586 C  CG  . LEU A 1 346 ? 45.75416  21.62702  -19.71644 1.000 63.06973  ? 346 LEU A CG  1 
ATOM   2587 C  CD1 . LEU A 1 346 ? 46.68210  22.63323  -20.37313 1.000 54.93593  ? 346 LEU A CD1 1 
ATOM   2588 C  CD2 . LEU A 1 346 ? 46.52952  20.71263  -18.78427 1.000 67.95611  ? 346 LEU A CD2 1 
ATOM   2589 N  N   . TYR A 1 347 ? 42.40283  22.67222  -16.36718 1.000 71.54391  ? 347 TYR A N   1 
ATOM   2590 C  CA  . TYR A 1 347 ? 42.15536  23.36059  -15.10041 1.000 62.32094  ? 347 TYR A CA  1 
ATOM   2591 C  C   . TYR A 1 347 ? 42.61223  22.57724  -13.87399 1.000 77.02122  ? 347 TYR A C   1 
ATOM   2592 O  O   . TYR A 1 347 ? 43.23770  23.18318  -12.98910 1.000 88.13630  ? 347 TYR A O   1 
ATOM   2593 C  CB  . TYR A 1 347 ? 40.66152  23.71304  -15.02262 1.000 62.11404  ? 347 TYR A CB  1 
ATOM   2594 C  CG  . TYR A 1 347 ? 40.20451  24.34186  -13.72144 1.000 74.66897  ? 347 TYR A CG  1 
ATOM   2595 C  CD1 . TYR A 1 347 ? 39.80218  23.55234  -12.65087 1.000 81.48641  ? 347 TYR A CD1 1 
ATOM   2596 C  CD2 . TYR A 1 347 ? 40.14372  25.72156  -13.57460 1.000 76.38416  ? 347 TYR A CD2 1 
ATOM   2597 C  CE1 . TYR A 1 347 ? 39.37578  24.11520  -11.46639 1.000 73.10999  ? 347 TYR A CE1 1 
ATOM   2598 C  CE2 . TYR A 1 347 ? 39.71379  26.29506  -12.38846 1.000 83.30481  ? 347 TYR A CE2 1 
ATOM   2599 C  CZ  . TYR A 1 347 ? 39.33149  25.48336  -11.33900 1.000 79.35512  ? 347 TYR A CZ  1 
ATOM   2600 O  OH  . TYR A 1 347 ? 38.90371  26.03425  -10.15371 1.000 85.68538  ? 347 TYR A OH  1 
ATOM   2601 N  N   . PRO A 1 348 ? 42.33611  21.27366  -13.73631 1.000 70.98325  ? 348 PRO A N   1 
ATOM   2602 C  CA  . PRO A 1 348 ? 42.78663  20.56400  -12.52550 1.000 63.90591  ? 348 PRO A CA  1 
ATOM   2603 C  C   . PRO A 1 348 ? 44.29703  20.54408  -12.33695 1.000 64.35601  ? 348 PRO A C   1 
ATOM   2604 O  O   . PRO A 1 348 ? 44.75411  20.39260  -11.19793 1.000 73.19776  ? 348 PRO A O   1 
ATOM   2605 C  CB  . PRO A 1 348 ? 42.22829  19.14741  -12.72087 1.000 80.01384  ? 348 PRO A CB  1 
ATOM   2606 C  CG  . PRO A 1 348 ? 41.07836  19.31986  -13.63884 1.000 70.64460  ? 348 PRO A CG  1 
ATOM   2607 C  CD  . PRO A 1 348 ? 41.48260  20.41111  -14.57564 1.000 68.40755  ? 348 PRO A CD  1 
ATOM   2608 N  N   . SER A 1 349 ? 45.08406  20.69445  -13.40420 1.000 66.31626  ? 349 SER A N   1 
ATOM   2609 C  CA  . SER A 1 349 ? 46.53639  20.60896  -13.29186 1.000 77.51087  ? 349 SER A CA  1 
ATOM   2610 C  C   . SER A 1 349 ? 47.19249  21.94043  -12.95796 1.000 81.97757  ? 349 SER A C   1 
ATOM   2611 O  O   . SER A 1 349 ? 48.20305  21.96123  -12.24347 1.000 85.48763  ? 349 SER A O   1 
ATOM   2612 C  CB  . SER A 1 349 ? 47.14155  20.05910  -14.58644 1.000 80.76943  ? 349 SER A CB  1 
ATOM   2613 O  OG  . SER A 1 349 ? 47.05762  21.00823  -15.63458 1.000 63.92963  ? 349 SER A OG  1 
ATOM   2614 N  N   . ILE A 1 350 ? 46.64308  23.05522  -13.44877 1.000 77.13290  ? 350 ILE A N   1 
ATOM   2615 C  CA  . ILE A 1 350 ? 47.22643  24.36796  -13.17942 1.000 72.58031  ? 350 ILE A CA  1 
ATOM   2616 C  C   . ILE A 1 350 ? 47.10883  24.77625  -11.72012 1.000 75.44328  ? 350 ILE A C   1 
ATOM   2617 O  O   . ILE A 1 350 ? 47.77491  25.72817  -11.29882 1.000 78.97047  ? 350 ILE A O   1 
ATOM   2618 C  CB  . ILE A 1 350 ? 46.57568  25.46311  -14.05029 1.000 80.92117  ? 350 ILE A CB  1 
ATOM   2619 C  CG1 . ILE A 1 350 ? 45.21239  25.87046  -13.48352 1.000 83.62118  ? 350 ILE A CG1 1 
ATOM   2620 C  CG2 . ILE A 1 350 ? 46.43333  24.99483  -15.49082 1.000 68.69554  ? 350 ILE A CG2 1 
ATOM   2621 C  CD1 . ILE A 1 350 ? 44.62105  27.09191  -14.14971 1.000 78.87340  ? 350 ILE A CD1 1 
ATOM   2622 N  N   . GLN A 1 351 ? 46.28022  24.08077  -10.94238 1.000 82.65727  ? 351 GLN A N   1 
ATOM   2623 C  CA  . GLN A 1 351 ? 46.10132  24.39993  -9.53608  1.000 80.34251  ? 351 GLN A CA  1 
ATOM   2624 C  C   . GLN A 1 351 ? 47.41145  24.22496  -8.76935  1.000 80.74842  ? 351 GLN A C   1 
ATOM   2625 O  O   . GLN A 1 351 ? 48.33084  23.52227  -9.19674  1.000 85.90344  ? 351 GLN A O   1 
ATOM   2626 C  CB  . GLN A 1 351 ? 45.01682  23.51393  -8.92369  1.000 76.71506  ? 351 GLN A CB  1 
ATOM   2627 C  CG  . GLN A 1 351 ? 43.74649  23.40249  -9.75718  1.000 77.33340  ? 351 GLN A CG  1 
ATOM   2628 C  CD  . GLN A 1 351 ? 42.86410  24.63236  -9.65906  1.000 79.30533  ? 351 GLN A CD  1 
ATOM   2629 O  OE1 . GLN A 1 351 ? 42.37758  24.97593  -8.58198  1.000 69.58085  ? 351 GLN A OE1 1 
ATOM   2630 N  NE2 . GLN A 1 351 ? 42.65147  25.30154  -10.78729 1.000 86.82640  ? 351 GLN A NE2 1 
ATOM   2631 N  N   . ASN A 1 352 ? 47.49040  24.89624  -7.62847  1.000 85.58054  ? 352 ASN A N   1 
ATOM   2632 C  CA  . ASN A 1 352 ? 48.63633  24.81894  -6.72379  1.000 90.16411  ? 352 ASN A CA  1 
ATOM   2633 C  C   . ASN A 1 352 ? 48.13287  24.42606  -5.34396  1.000 79.37873  ? 352 ASN A C   1 
ATOM   2634 O  O   . ASN A 1 352 ? 47.43948  25.22956  -4.69057  1.000 75.81835  ? 352 ASN A O   1 
ATOM   2635 C  CB  . ASN A 1 352 ? 49.38519  26.14921  -6.65999  1.000 93.09408  ? 352 ASN A CB  1 
ATOM   2636 C  CG  . ASN A 1 352 ? 50.63629  26.06997  -5.80918  1.000 109.22864 ? 352 ASN A CG  1 
ATOM   2637 O  OD1 . ASN A 1 352 ? 51.47513  25.19099  -6.00167  1.000 103.79232 ? 352 ASN A OD1 1 
ATOM   2638 N  ND2 . ASN A 1 352 ? 50.76176  26.98311  -4.85171  1.000 116.65458 ? 352 ASN A ND2 1 
ATOM   2639 N  N   . PRO A 1 353 ? 48.42587  23.21486  -4.86088  1.000 85.67260  ? 353 PRO A N   1 
ATOM   2640 C  CA  . PRO A 1 353 ? 49.19242  22.15160  -5.52594  1.000 79.13500  ? 353 PRO A CA  1 
ATOM   2641 C  C   . PRO A 1 353 ? 48.41506  21.54260  -6.68720  1.000 84.80415  ? 353 PRO A C   1 
ATOM   2642 O  O   . PRO A 1 353 ? 47.18660  21.58655  -6.70082  1.000 78.06214  ? 353 PRO A O   1 
ATOM   2643 C  CB  . PRO A 1 353 ? 49.42810  21.14353  -4.39432  1.000 81.31111  ? 353 PRO A CB  1 
ATOM   2644 C  CG  . PRO A 1 353 ? 48.23587  21.31642  -3.49799  1.000 88.29735  ? 353 PRO A CG  1 
ATOM   2645 C  CD  . PRO A 1 353 ? 47.93443  22.79287  -3.53673  1.000 99.35088  ? 353 PRO A CD  1 
ATOM   2646 N  N   . PRO A 1 354 ? 49.10811  20.99216  -7.68324  1.000 88.14788  ? 354 PRO A N   1 
ATOM   2647 C  CA  . PRO A 1 354 ? 48.40378  20.40244  -8.82738  1.000 80.72598  ? 354 PRO A CA  1 
ATOM   2648 C  C   . PRO A 1 354 ? 47.50526  19.25441  -8.39611  1.000 78.17425  ? 354 PRO A C   1 
ATOM   2649 O  O   . PRO A 1 354 ? 47.84762  18.46796  -7.51058  1.000 68.86156  ? 354 PRO A O   1 
ATOM   2650 C  CB  . PRO A 1 354 ? 49.54168  19.91894  -9.73373  1.000 78.87037  ? 354 PRO A CB  1 
ATOM   2651 C  CG  . PRO A 1 354 ? 50.71784  20.76351  -9.34595  1.000 78.60143  ? 354 PRO A CG  1 
ATOM   2652 C  CD  . PRO A 1 354 ? 50.56917  20.98641  -7.86902  1.000 86.43137  ? 354 PRO A CD  1 
ATOM   2653 N  N   . TYR A 1 355 ? 46.34563  19.16727  -9.03671  1.000 74.04400  ? 355 TYR A N   1 
ATOM   2654 C  CA  . TYR A 1 355 ? 45.38221  18.10834  -8.79198  1.000 75.07080  ? 355 TYR A CA  1 
ATOM   2655 C  C   . TYR A 1 355 ? 45.30498  17.19981  -10.01025 1.000 74.31504  ? 355 TYR A C   1 
ATOM   2656 O  O   . TYR A 1 355 ? 45.68144  17.57913  -11.12279 1.000 76.92461  ? 355 TYR A O   1 
ATOM   2657 C  CB  . TYR A 1 355 ? 43.99761  18.68615  -8.47246  1.000 69.08395  ? 355 TYR A CB  1 
ATOM   2658 C  CG  . TYR A 1 355 ? 42.98458  17.65756  -8.01760  1.000 78.38521  ? 355 TYR A CG  1 
ATOM   2659 C  CD1 . TYR A 1 355 ? 43.21238  16.87822  -6.89019  1.000 73.31152  ? 355 TYR A CD1 1 
ATOM   2660 C  CD2 . TYR A 1 355 ? 41.79620  17.47255  -8.71225  1.000 83.57591  ? 355 TYR A CD2 1 
ATOM   2661 C  CE1 . TYR A 1 355 ? 42.28626  15.93941  -6.47160  1.000 77.22037  ? 355 TYR A CE1 1 
ATOM   2662 C  CE2 . TYR A 1 355 ? 40.86621  16.53913  -8.30185  1.000 85.18513  ? 355 TYR A CE2 1 
ATOM   2663 C  CZ  . TYR A 1 355 ? 41.11473  15.77597  -7.18303  1.000 81.01191  ? 355 TYR A CZ  1 
ATOM   2664 O  OH  . TYR A 1 355 ? 40.18486  14.84772  -6.77700  1.000 79.74158  ? 355 TYR A OH  1 
ATOM   2665 N  N   . ARG A 1 356 ? 44.81582  15.98639  -9.78540  1.000 73.40120  ? 356 ARG A N   1 
ATOM   2666 C  CA  . ARG A 1 356 ? 44.66778  14.98835  -10.83920 1.000 78.78441  ? 356 ARG A CA  1 
ATOM   2667 C  C   . ARG A 1 356 ? 43.20767  14.55704  -10.89080 1.000 76.93512  ? 356 ARG A C   1 
ATOM   2668 O  O   . ARG A 1 356 ? 42.75217  13.78355  -10.04254 1.000 82.14279  ? 356 ARG A O   1 
ATOM   2669 C  CB  . ARG A 1 356 ? 45.58377  13.79354  -10.59622 1.000 78.45595  ? 356 ARG A CB  1 
ATOM   2670 C  CG  . ARG A 1 356 ? 47.04807  14.03684  -10.91025 1.000 71.65911  ? 356 ARG A CG  1 
ATOM   2671 C  CD  . ARG A 1 356 ? 47.87681  12.84782  -10.46128 1.000 93.89368  ? 356 ARG A CD  1 
ATOM   2672 N  NE  . ARG A 1 356 ? 47.27117  11.58838  -10.87832 1.000 126.53905 ? 356 ARG A NE  1 
ATOM   2673 C  CZ  . ARG A 1 356 ? 47.57862  10.40301  -10.36924 1.000 125.44555 ? 356 ARG A CZ  1 
ATOM   2674 N  NH1 . ARG A 1 356 ? 48.48148  10.27545  -9.41071  1.000 111.35147 ? 356 ARG A NH1 1 
ATOM   2675 N  NH2 . ARG A 1 356 ? 46.96007  9.31920   -10.82933 1.000 121.64378 ? 356 ARG A NH2 1 
ATOM   2676 N  N   . LEU A 1 357 ? 42.47141  15.06252  -11.87902 1.000 74.11766  ? 357 LEU A N   1 
ATOM   2677 C  CA  . LEU A 1 357 ? 41.15968  14.51765  -12.19083 1.000 70.58691  ? 357 LEU A CA  1 
ATOM   2678 C  C   . LEU A 1 357 ? 41.34400  13.45319  -13.26194 1.000 74.14058  ? 357 LEU A C   1 
ATOM   2679 O  O   . LEU A 1 357 ? 41.68984  13.79482  -14.40373 1.000 79.86550  ? 357 LEU A O   1 
ATOM   2680 C  CB  . LEU A 1 357 ? 40.21236  15.60358  -12.67646 1.000 61.42463  ? 357 LEU A CB  1 
ATOM   2681 C  CG  . LEU A 1 357 ? 38.82115  15.07206  -13.03317 1.000 54.61384  ? 357 LEU A CG  1 
ATOM   2682 C  CD1 . LEU A 1 357 ? 38.11582  14.53711  -11.79347 1.000 54.53928  ? 357 LEU A CD1 1 
ATOM   2683 C  CD2 . LEU A 1 357 ? 37.97852  16.13111  -13.72408 1.000 49.35261  ? 357 LEU A CD2 1 
ATOM   2684 N  N   . PRO A 1 358 ? 41.14503  12.17323  -12.95356 1.000 64.19009  ? 358 PRO A N   1 
ATOM   2685 C  CA  . PRO A 1 358 ? 41.30732  11.13770  -13.97904 1.000 67.33952  ? 358 PRO A CA  1 
ATOM   2686 C  C   . PRO A 1 358 ? 40.30252  11.32040  -15.10619 1.000 61.90464  ? 358 PRO A C   1 
ATOM   2687 O  O   . PRO A 1 358 ? 39.18938  11.80864  -14.90303 1.000 61.65941  ? 358 PRO A O   1 
ATOM   2688 C  CB  . PRO A 1 358 ? 41.05972  9.83457   -13.20910 1.000 70.41620  ? 358 PRO A CB  1 
ATOM   2689 C  CG  . PRO A 1 358 ? 41.34652  10.18302  -11.77923 1.000 58.28814  ? 358 PRO A CG  1 
ATOM   2690 C  CD  . PRO A 1 358 ? 40.87182  11.59663  -11.62696 1.000 55.84614  ? 358 PRO A CD  1 
ATOM   2691 N  N   . TYR A 1 359 ? 40.71235  10.92703  -16.30999 1.000 60.42878  ? 359 TYR A N   1 
ATOM   2692 C  CA  . TYR A 1 359 ? 39.89228  11.08683  -17.50062 1.000 69.13390  ? 359 TYR A CA  1 
ATOM   2693 C  C   . TYR A 1 359 ? 39.70056  9.74347   -18.18936 1.000 72.16145  ? 359 TYR A C   1 
ATOM   2694 O  O   . TYR A 1 359 ? 40.55959  8.85992   -18.12140 1.000 68.44658  ? 359 TYR A O   1 
ATOM   2695 C  CB  . TYR A 1 359 ? 40.50873  12.09177  -18.48202 1.000 67.25692  ? 359 TYR A CB  1 
ATOM   2696 C  CG  . TYR A 1 359 ? 40.43713  13.53172  -18.02385 1.000 62.84998  ? 359 TYR A CG  1 
ATOM   2697 C  CD1 . TYR A 1 359 ? 39.21463  14.14185  -17.77726 1.000 60.91084  ? 359 TYR A CD1 1 
ATOM   2698 C  CD2 . TYR A 1 359 ? 41.59134  14.28647  -17.85751 1.000 58.43819  ? 359 TYR A CD2 1 
ATOM   2699 C  CE1 . TYR A 1 359 ? 39.14320  15.45883  -17.36408 1.000 59.68408  ? 359 TYR A CE1 1 
ATOM   2700 C  CE2 . TYR A 1 359 ? 41.52998  15.60584  -17.44614 1.000 61.23783  ? 359 TYR A CE2 1 
ATOM   2701 C  CZ  . TYR A 1 359 ? 40.30334  16.18662  -17.20142 1.000 65.69848  ? 359 TYR A CZ  1 
ATOM   2702 O  OH  . TYR A 1 359 ? 40.23513  17.49891  -16.79195 1.000 68.59749  ? 359 TYR A OH  1 
ATOM   2703 N  N   . PHE A 1 360 ? 38.55119  9.59845   -18.84448 1.000 67.04219  ? 360 PHE A N   1 
ATOM   2704 C  CA  . PHE A 1 360 ? 38.15766  8.35652   -19.50915 1.000 68.23763  ? 360 PHE A CA  1 
ATOM   2705 C  C   . PHE A 1 360 ? 37.58437  8.67083   -20.89135 1.000 63.05668  ? 360 PHE A C   1 
ATOM   2706 O  O   . PHE A 1 360 ? 36.49871  8.22345   -21.26011 1.000 69.38344  ? 360 PHE A O   1 
ATOM   2707 C  CB  . PHE A 1 360 ? 37.17205  7.57587   -18.64025 1.000 59.23765  ? 360 PHE A CB  1 
ATOM   2708 C  CG  . PHE A 1 360 ? 37.75267  7.12862   -17.32273 1.000 58.04737  ? 360 PHE A CG  1 
ATOM   2709 C  CD1 . PHE A 1 360 ? 37.71160  7.95525   -16.21014 1.000 59.97559  ? 360 PHE A CD1 1 
ATOM   2710 C  CD2 . PHE A 1 360 ? 38.34514  5.88274   -17.19995 1.000 70.51626  ? 360 PHE A CD2 1 
ATOM   2711 C  CE1 . PHE A 1 360 ? 38.24891  7.54486   -15.00142 1.000 59.19564  ? 360 PHE A CE1 1 
ATOM   2712 C  CE2 . PHE A 1 360 ? 38.88314  5.46729   -15.99421 1.000 68.66949  ? 360 PHE A CE2 1 
ATOM   2713 C  CZ  . PHE A 1 360 ? 38.83450  6.29949   -14.89418 1.000 60.89212  ? 360 PHE A CZ  1 
ATOM   2714 N  N   . PHE A 1 361 ? 38.33347  9.45213   -21.67137 1.000 56.06589  ? 361 PHE A N   1 
ATOM   2715 C  CA  . PHE A 1 361 ? 37.79559  10.08039  -22.87423 1.000 72.27850  ? 361 PHE A CA  1 
ATOM   2716 C  C   . PHE A 1 361 ? 37.37265  9.07125   -23.93571 1.000 63.45653  ? 361 PHE A C   1 
ATOM   2717 O  O   . PHE A 1 361 ? 38.04957  8.06836   -24.17234 1.000 69.84403  ? 361 PHE A O   1 
ATOM   2718 C  CB  . PHE A 1 361 ? 38.83189  11.02459  -23.48826 1.000 74.79959  ? 361 PHE A CB  1 
ATOM   2719 C  CG  . PHE A 1 361 ? 39.07563  12.26944  -22.69144 1.000 66.47662  ? 361 PHE A CG  1 
ATOM   2720 C  CD1 . PHE A 1 361 ? 38.04890  13.16486  -22.44504 1.000 59.61810  ? 361 PHE A CD1 1 
ATOM   2721 C  CD2 . PHE A 1 361 ? 40.34137  12.55993  -22.21366 1.000 63.73822  ? 361 PHE A CD2 1 
ATOM   2722 C  CE1 . PHE A 1 361 ? 38.27785  14.31705  -21.71981 1.000 68.77376  ? 361 PHE A CE1 1 
ATOM   2723 C  CE2 . PHE A 1 361 ? 40.57818  13.71058  -21.49135 1.000 58.48362  ? 361 PHE A CE2 1 
ATOM   2724 C  CZ  . PHE A 1 361 ? 39.54469  14.59013  -21.24148 1.000 67.38628  ? 361 PHE A CZ  1 
ATOM   2725 N  N   . HIS A 1 362 ? 36.24165  9.35568   -24.58243 1.000 61.77470  ? 362 HIS A N   1 
ATOM   2726 C  CA  . HIS A 1 362 ? 36.01777  8.86301   -25.93399 1.000 60.36545  ? 362 HIS A CA  1 
ATOM   2727 C  C   . HIS A 1 362 ? 37.04817  9.50000   -26.85742 1.000 71.10489  ? 362 HIS A C   1 
ATOM   2728 O  O   . HIS A 1 362 ? 37.40259  10.67072  -26.69376 1.000 73.91726  ? 362 HIS A O   1 
ATOM   2729 C  CB  . HIS A 1 362 ? 34.61081  9.21913   -26.42536 1.000 69.89027  ? 362 HIS A CB  1 
ATOM   2730 C  CG  . HIS A 1 362 ? 33.50649  8.44363   -25.77408 1.000 62.36217  ? 362 HIS A CG  1 
ATOM   2731 N  ND1 . HIS A 1 362 ? 33.46466  8.18737   -24.42060 1.000 61.57088  ? 362 HIS A ND1 1 
ATOM   2732 C  CD2 . HIS A 1 362 ? 32.38321  7.89408   -26.29455 1.000 62.69535  ? 362 HIS A CD2 1 
ATOM   2733 C  CE1 . HIS A 1 362 ? 32.37118  7.50121   -24.13752 1.000 60.67700  ? 362 HIS A CE1 1 
ATOM   2734 N  NE2 . HIS A 1 362 ? 31.69754  7.31131   -25.25737 1.000 60.68389  ? 362 HIS A NE2 1 
ATOM   2735 N  N   . ALA A 1 363 ? 37.53128  8.73730   -27.83703 1.000 63.68562  ? 363 ALA A N   1 
ATOM   2736 C  CA  . ALA A 1 363 ? 38.52425  9.28542   -28.75362 1.000 65.64060  ? 363 ALA A CA  1 
ATOM   2737 C  C   . ALA A 1 363 ? 38.54618  8.48135   -30.04340 1.000 66.85245  ? 363 ALA A C   1 
ATOM   2738 O  O   . ALA A 1 363 ? 38.52442  7.24736   -30.00821 1.000 70.93757  ? 363 ALA A O   1 
ATOM   2739 C  CB  . ALA A 1 363 ? 39.91649  9.29918   -28.11278 1.000 66.47253  ? 363 ALA A CB  1 
ATOM   2740 N  N   . ALA A 1 364 ? 38.58716  9.19228   -31.17322 1.000 68.82043  ? 364 ALA A N   1 
ATOM   2741 C  CA  . ALA A 1 364 ? 38.81101  8.59938   -32.49339 1.000 65.05393  ? 364 ALA A CA  1 
ATOM   2742 C  C   . ALA A 1 364 ? 37.72449  7.59170   -32.86629 1.000 67.77961  ? 364 ALA A C   1 
ATOM   2743 O  O   . ALA A 1 364 ? 37.99700  6.56693   -33.49373 1.000 74.10428  ? 364 ALA A O   1 
ATOM   2744 C  CB  . ALA A 1 364 ? 40.19812  7.95692   -32.57819 1.000 52.97725  ? 364 ALA A CB  1 
ATOM   2745 N  N   . GLU A 1 365 ? 36.47907  7.88282   -32.48801 1.000 61.83733  ? 365 GLU A N   1 
ATOM   2746 C  CA  . GLU A 1 365 ? 35.33419  7.07233   -32.90495 1.000 58.03043  ? 365 GLU A CA  1 
ATOM   2747 C  C   . GLU A 1 365 ? 34.86250  7.51796   -34.29286 1.000 63.17731  ? 365 GLU A C   1 
ATOM   2748 O  O   . GLU A 1 365 ? 33.74864  8.00522   -34.48568 1.000 60.87261  ? 365 GLU A O   1 
ATOM   2749 C  CB  . GLU A 1 365 ? 34.21468  7.16864   -31.87523 1.000 52.88666  ? 365 GLU A CB  1 
ATOM   2750 C  CG  . GLU A 1 365 ? 33.10574  6.13897   -32.04743 1.000 61.91273  ? 365 GLU A CG  1 
ATOM   2751 C  CD  . GLU A 1 365 ? 31.94050  6.36997   -31.10387 1.000 66.98498  ? 365 GLU A CD  1 
ATOM   2752 O  OE1 . GLU A 1 365 ? 31.89522  7.44269   -30.46643 1.000 70.54981  ? 365 GLU A OE1 1 
ATOM   2753 O  OE2 . GLU A 1 365 ? 31.06911  5.48034   -31.00034 1.000 65.45651  ? 365 GLU A OE2 1 
ATOM   2754 N  N   . THR A 1 366 ? 35.74671  7.34725   -35.27382 1.000 67.10627  ? 366 THR A N   1 
ATOM   2755 C  CA  . THR A 1 366 ? 35.51166  7.92601   -36.58853 1.000 66.84522  ? 366 THR A CA  1 
ATOM   2756 C  C   . THR A 1 366 ? 36.29333  7.15980   -37.64510 1.000 68.77148  ? 366 THR A C   1 
ATOM   2757 O  O   . THR A 1 366 ? 37.26548  6.46082   -37.34671 1.000 71.65821  ? 366 THR A O   1 
ATOM   2758 C  CB  . THR A 1 366 ? 35.90520  9.40656   -36.61955 1.000 57.52154  ? 366 THR A CB  1 
ATOM   2759 O  OG1 . THR A 1 366 ? 35.53508  9.97069   -37.88189 1.000 63.56786  ? 366 THR A OG1 1 
ATOM   2760 C  CG2 . THR A 1 366 ? 37.40872  9.55998   -36.42359 1.000 53.80332  ? 366 THR A CG2 1 
ATOM   2761 N  N   . ASN A 1 367 ? 35.84141  7.30054   -38.88969 1.000 58.82275  ? 367 ASN A N   1 
ATOM   2762 C  CA  . ASN A 1 367 ? 36.56816  6.82766   -40.05889 1.000 56.26876  ? 367 ASN A CA  1 
ATOM   2763 C  C   . ASN A 1 367 ? 37.47803  7.89460   -40.65500 1.000 70.15207  ? 367 ASN A C   1 
ATOM   2764 O  O   . ASN A 1 367 ? 38.17072  7.61723   -41.63880 1.000 69.43047  ? 367 ASN A O   1 
ATOM   2765 C  CB  . ASN A 1 367 ? 35.59027  6.34369   -41.13618 1.000 52.59261  ? 367 ASN A CB  1 
ATOM   2766 C  CG  . ASN A 1 367 ? 34.63250  5.28648   -40.62778 1.000 50.42955  ? 367 ASN A CG  1 
ATOM   2767 O  OD1 . ASN A 1 367 ? 33.41469  5.44297   -40.71649 1.000 54.31416  ? 367 ASN A OD1 1 
ATOM   2768 N  ND2 . ASN A 1 367 ? 35.17738  4.19774   -40.10093 1.000 64.64827  ? 367 ASN A ND2 1 
ATOM   2769 N  N   . TRP A 1 368 ? 37.47535  9.10652   -40.10569 1.000 64.40476  ? 368 TRP A N   1 
ATOM   2770 C  CA  . TRP A 1 368 ? 38.30033  10.18109  -40.63313 1.000 51.36838  ? 368 TRP A CA  1 
ATOM   2771 C  C   . TRP A 1 368 ? 39.75066  10.01496  -40.18829 1.000 58.88733  ? 368 TRP A C   1 
ATOM   2772 O  O   . TRP A 1 368 ? 40.05055  9.37881   -39.17455 1.000 65.64363  ? 368 TRP A O   1 
ATOM   2773 C  CB  . TRP A 1 368 ? 37.76439  11.54359  -40.19017 1.000 54.31145  ? 368 TRP A CB  1 
ATOM   2774 C  CG  . TRP A 1 368 ? 36.39192  11.85220  -40.71390 1.000 52.82875  ? 368 TRP A CG  1 
ATOM   2775 C  CD1 . TRP A 1 368 ? 35.25952  12.05440  -39.98058 1.000 51.60306  ? 368 TRP A CD1 1 
ATOM   2776 C  CD2 . TRP A 1 368 ? 36.00847  11.98658  -42.08762 1.000 52.01804  ? 368 TRP A CD2 1 
ATOM   2777 N  NE1 . TRP A 1 368 ? 34.19578  12.31038  -40.81107 1.000 59.54323  ? 368 TRP A NE1 1 
ATOM   2778 C  CE2 . TRP A 1 368 ? 34.62918  12.27369  -42.11012 1.000 55.00059  ? 368 TRP A CE2 1 
ATOM   2779 C  CE3 . TRP A 1 368 ? 36.69809  11.89467  -43.30062 1.000 54.05032  ? 368 TRP A CE3 1 
ATOM   2780 C  CZ2 . TRP A 1 368 ? 33.92673  12.46922  -43.29742 1.000 56.60550  ? 368 TRP A CZ2 1 
ATOM   2781 C  CZ3 . TRP A 1 368 ? 35.99927  12.08833  -44.47736 1.000 52.59871  ? 368 TRP A CZ3 1 
ATOM   2782 C  CH2 . TRP A 1 368 ? 34.62828  12.37256  -44.46750 1.000 54.10504  ? 368 TRP A CH2 1 
ATOM   2783 N  N   . GLN A 1 369 ? 40.65829  10.60156  -40.96680 1.000 56.34370  ? 369 GLN A N   1 
ATOM   2784 C  CA  . GLN A 1 369 ? 42.08806  10.51065  -40.70615 1.000 59.77196  ? 369 GLN A CA  1 
ATOM   2785 C  C   . GLN A 1 369 ? 42.71755  11.89463  -40.79180 1.000 61.24812  ? 369 GLN A C   1 
ATOM   2786 O  O   . GLN A 1 369 ? 42.42353  12.66188  -41.71367 1.000 70.92759  ? 369 GLN A O   1 
ATOM   2787 C  CB  . GLN A 1 369 ? 42.76884  9.55637   -41.69288 1.000 62.94598  ? 369 GLN A CB  1 
ATOM   2788 C  CG  . GLN A 1 369 ? 44.21484  9.24940   -41.35522 1.000 60.83809  ? 369 GLN A CG  1 
ATOM   2789 C  CD  . GLN A 1 369 ? 44.86125  8.32869   -42.36727 1.000 61.34084  ? 369 GLN A CD  1 
ATOM   2790 O  OE1 . GLN A 1 369 ? 44.21928  7.89011   -43.32163 1.000 55.09453  ? 369 GLN A OE1 1 
ATOM   2791 N  NE2 . GLN A 1 369 ? 46.13995  8.03148   -42.16616 1.000 69.96659  ? 369 GLN A NE2 1 
ATOM   2792 N  N   . GLU A 1 370 ? 43.58619  12.20150  -39.82349 1.000 67.45852  ? 370 GLU A N   1 
ATOM   2793 C  CA  . GLU A 1 370 ? 44.26323  13.49702  -39.72519 1.000 70.28075  ? 370 GLU A CA  1 
ATOM   2794 C  C   . GLU A 1 370 ? 43.26732  14.65524  -39.68292 1.000 63.19841  ? 370 GLU A C   1 
ATOM   2795 O  O   . GLU A 1 370 ? 43.43995  15.67233  -40.35701 1.000 73.93997  ? 370 GLU A O   1 
ATOM   2796 C  CB  . GLU A 1 370 ? 45.27318  13.68741  -40.85962 1.000 69.68238  ? 370 GLU A CB  1 
ATOM   2797 C  CG  . GLU A 1 370 ? 46.51202  12.81503  -40.73202 1.000 75.53770  ? 370 GLU A CG  1 
ATOM   2798 C  CD  . GLU A 1 370 ? 47.52093  13.05847  -41.83855 1.000 82.11724  ? 370 GLU A CD  1 
ATOM   2799 O  OE1 . GLU A 1 370 ? 47.24999  13.89461  -42.72647 1.000 75.85395  ? 370 GLU A OE1 1 
ATOM   2800 O  OE2 . GLU A 1 370 ? 48.58955  12.41296  -41.81819 1.000 80.62107  ? 370 GLU A OE2 1 
ATOM   2801 N  N   . THR A 1 371 ? 42.21636  14.49969  -38.88399 1.000 66.19495  ? 371 THR A N   1 
ATOM   2802 C  CA  . THR A 1 371 ? 41.21802  15.53553  -38.63918 1.000 64.32938  ? 371 THR A CA  1 
ATOM   2803 C  C   . THR A 1 371 ? 41.15372  15.84215  -37.14368 1.000 67.02883  ? 371 THR A C   1 
ATOM   2804 O  O   . THR A 1 371 ? 41.89332  15.27180  -36.33944 1.000 62.94898  ? 371 THR A O   1 
ATOM   2805 C  CB  . THR A 1 371 ? 39.84334  15.11047  -39.16511 1.000 56.66201  ? 371 THR A CB  1 
ATOM   2806 O  OG1 . THR A 1 371 ? 39.45295  13.88002  -38.54443 1.000 60.59033  ? 371 THR A OG1 1 
ATOM   2807 C  CG2 . THR A 1 371 ? 39.88507  14.92064  -40.67065 1.000 51.60679  ? 371 THR A CG2 1 
ATOM   2808 N  N   . GLU A 1 372 ? 40.25095  16.75762  -36.77580 1.000 67.24389  ? 372 GLU A N   1 
ATOM   2809 C  CA  . GLU A 1 372 ? 40.04989  17.08516  -35.36554 1.000 79.08124  ? 372 GLU A CA  1 
ATOM   2810 C  C   . GLU A 1 372 ? 39.62575  15.85834  -34.56919 1.000 73.38045  ? 372 GLU A C   1 
ATOM   2811 O  O   . GLU A 1 372 ? 40.16567  15.58415  -33.49122 1.000 78.51156  ? 372 GLU A O   1 
ATOM   2812 C  CB  . GLU A 1 372 ? 38.99625  18.18251  -35.22371 1.000 85.20864  ? 372 GLU A CB  1 
ATOM   2813 C  CG  . GLU A 1 372 ? 39.48994  19.59440  -35.44237 1.000 84.51623  ? 372 GLU A CG  1 
ATOM   2814 C  CD  . GLU A 1 372 ? 38.38508  20.61177  -35.24069 1.000 87.62092  ? 372 GLU A CD  1 
ATOM   2815 O  OE1 . GLU A 1 372 ? 37.23203  20.19150  -35.00488 1.000 81.22790  ? 372 GLU A OE1 1 
ATOM   2816 O  OE2 . GLU A 1 372 ? 38.66500  21.82641  -35.31541 1.000 101.40178 ? 372 GLU A OE2 1 
ATOM   2817 N  N   . VAL A 1 373 ? 38.64672  15.11311  -35.08579 1.000 70.17626  ? 373 VAL A N   1 
ATOM   2818 C  CA  . VAL A 1 373 ? 38.14295  13.93607  -34.38207 1.000 66.42763  ? 373 VAL A CA  1 
ATOM   2819 C  C   . VAL A 1 373 ? 39.25540  12.91174  -34.20719 1.000 64.99472  ? 373 VAL A C   1 
ATOM   2820 O  O   . VAL A 1 373 ? 39.45077  12.35120  -33.12204 1.000 67.37390  ? 373 VAL A O   1 
ATOM   2821 C  CB  . VAL A 1 373 ? 36.94533  13.33685  -35.14076 1.000 57.92303  ? 373 VAL A CB  1 
ATOM   2822 C  CG1 . VAL A 1 373 ? 36.25424  12.27934  -34.29959 1.000 67.27985  ? 373 VAL A CG1 1 
ATOM   2823 C  CG2 . VAL A 1 373 ? 35.97144  14.43173  -35.54995 1.000 59.08801  ? 373 VAL A CG2 1 
ATOM   2824 N  N   . ASP A 1 374 ? 40.00270  12.65804  -35.28180 1.000 63.16007  ? 374 ASP A N   1 
ATOM   2825 C  CA  . ASP A 1 374 ? 41.09974  11.69949  -35.23591 1.000 67.17216  ? 374 ASP A CA  1 
ATOM   2826 C  C   . ASP A 1 374 ? 42.19464  12.14225  -34.27274 1.000 67.66223  ? 374 ASP A C   1 
ATOM   2827 O  O   . ASP A 1 374 ? 42.83689  11.30109  -33.63344 1.000 57.41759  ? 374 ASP A O   1 
ATOM   2828 C  CB  . ASP A 1 374 ? 41.65620  11.51290  -36.64908 1.000 56.73898  ? 374 ASP A CB  1 
ATOM   2829 C  CG  . ASP A 1 374 ? 42.69387  10.41272  -36.74038 1.000 73.40118  ? 374 ASP A CG  1 
ATOM   2830 O  OD1 . ASP A 1 374 ? 42.81834  9.60774   -35.79497 1.000 87.79077  ? 374 ASP A OD1 1 
ATOM   2831 O  OD2 . ASP A 1 374 ? 43.37831  10.34652  -37.78248 1.000 75.83291  ? 374 ASP A OD2 1 
ATOM   2832 N  N   . TYR A 1 375 ? 42.41648  13.44898  -34.14957 1.000 73.41076  ? 375 TYR A N   1 
ATOM   2833 C  CA  . TYR A 1 375 ? 43.49568  13.98889  -33.33215 1.000 63.73976  ? 375 TYR A CA  1 
ATOM   2834 C  C   . TYR A 1 375 ? 43.11492  14.18056  -31.86939 1.000 70.23908  ? 375 TYR A C   1 
ATOM   2835 O  O   . TYR A 1 375 ? 43.96990  14.58775  -31.07545 1.000 77.90897  ? 375 TYR A O   1 
ATOM   2836 C  CB  . TYR A 1 375 ? 43.98539  15.32030  -33.91377 1.000 63.31248  ? 375 TYR A CB  1 
ATOM   2837 C  CG  . TYR A 1 375 ? 45.00857  15.16796  -35.01859 1.000 65.53859  ? 375 TYR A CG  1 
ATOM   2838 C  CD1 . TYR A 1 375 ? 46.08502  14.30101  -34.88138 1.000 74.59541  ? 375 TYR A CD1 1 
ATOM   2839 C  CD2 . TYR A 1 375 ? 44.89681  15.88998  -36.19934 1.000 64.05484  ? 375 TYR A CD2 1 
ATOM   2840 C  CE1 . TYR A 1 375 ? 47.02360  14.16043  -35.88817 1.000 69.65950  ? 375 TYR A CE1 1 
ATOM   2841 C  CE2 . TYR A 1 375 ? 45.82915  15.75435  -37.21242 1.000 63.06857  ? 375 TYR A CE2 1 
ATOM   2842 C  CZ  . TYR A 1 375 ? 46.89005  14.88871  -37.05117 1.000 67.08141  ? 375 TYR A CZ  1 
ATOM   2843 O  OH  . TYR A 1 375 ? 47.82118  14.74969  -38.05529 1.000 73.17936  ? 375 TYR A OH  1 
ATOM   2844 N  N   . ASN A 1 376 ? 41.86505  13.89779  -31.48687 1.000 74.16505  ? 376 ASN A N   1 
ATOM   2845 C  CA  . ASN A 1 376 ? 41.52196  13.88432  -30.06821 1.000 71.32609  ? 376 ASN A CA  1 
ATOM   2846 C  C   . ASN A 1 376 ? 42.32618  12.83215  -29.32193 1.000 67.65157  ? 376 ASN A C   1 
ATOM   2847 O  O   . ASN A 1 376 ? 42.39919  12.87085  -28.08922 1.000 79.45763  ? 376 ASN A O   1 
ATOM   2848 C  CB  . ASN A 1 376 ? 40.02266  13.63366  -29.86985 1.000 69.31696  ? 376 ASN A CB  1 
ATOM   2849 C  CG  . ASN A 1 376 ? 39.16971  14.82959  -30.25886 1.000 72.87172  ? 376 ASN A CG  1 
ATOM   2850 O  OD1 . ASN A 1 376 ? 39.66695  15.94798  -30.39477 1.000 87.03829  ? 376 ASN A OD1 1 
ATOM   2851 N  ND2 . ASN A 1 376 ? 37.87200  14.59707  -30.42983 1.000 64.47717  ? 376 ASN A ND2 1 
ATOM   2852 N  N   . LEU A 1 377 ? 42.91627  11.88910  -30.05693 1.000 70.39182  ? 377 LEU A N   1 
ATOM   2853 C  CA  . LEU A 1 377 ? 43.78119  10.87902  -29.46522 1.000 74.21751  ? 377 LEU A CA  1 
ATOM   2854 C  C   . LEU A 1 377 ? 45.00482  11.50746  -28.80862 1.000 78.46287  ? 377 LEU A C   1 
ATOM   2855 O  O   . LEU A 1 377 ? 45.38891  11.12347  -27.69704 1.000 80.06780  ? 377 LEU A O   1 
ATOM   2856 C  CB  . LEU A 1 377 ? 44.20170  9.89783   -30.55430 1.000 64.31271  ? 377 LEU A CB  1 
ATOM   2857 C  CG  . LEU A 1 377 ? 44.26134  8.40442   -30.26927 1.000 68.60703  ? 377 LEU A CG  1 
ATOM   2858 C  CD1 . LEU A 1 377 ? 43.03973  7.94929   -29.50093 1.000 63.90687  ? 377 LEU A CD1 1 
ATOM   2859 C  CD2 . LEU A 1 377 ? 44.33234  7.71692   -31.60661 1.000 65.76101  ? 377 LEU A CD2 1 
ATOM   2860 N  N   . ALA A 1 378 ? 45.63553  12.47292  -29.48362 1.000 68.54027  ? 378 ALA A N   1 
ATOM   2861 C  CA  . ALA A 1 378 ? 46.81912  13.11662  -28.92154 1.000 68.09345  ? 378 ALA A CA  1 
ATOM   2862 C  C   . ALA A 1 378 ? 46.47765  13.91083  -27.66744 1.000 77.19013  ? 378 ALA A C   1 
ATOM   2863 O  O   . ALA A 1 378 ? 47.21786  13.86654  -26.67863 1.000 65.93262  ? 378 ALA A O   1 
ATOM   2864 C  CB  . ALA A 1 378 ? 47.47378  14.01840  -29.96864 1.000 47.38614  ? 378 ALA A CB  1 
ATOM   2865 N  N   . ASP A 1 379 ? 45.36093  14.64218  -27.68888 1.000 72.67799  ? 379 ASP A N   1 
ATOM   2866 C  CA  . ASP A 1 379 ? 44.94867  15.39834  -26.51091 1.000 66.14424  ? 379 ASP A CA  1 
ATOM   2867 C  C   . ASP A 1 379 ? 44.66060  14.47614  -25.33485 1.000 71.53355  ? 379 ASP A C   1 
ATOM   2868 O  O   . ASP A 1 379 ? 45.03567  14.77710  -24.19756 1.000 74.79789  ? 379 ASP A O   1 
ATOM   2869 C  CB  . ASP A 1 379 ? 43.72493  16.25199  -26.83742 1.000 65.39257  ? 379 ASP A CB  1 
ATOM   2870 C  CG  . ASP A 1 379 ? 44.02710  17.33138  -27.85428 1.000 85.20434  ? 379 ASP A CG  1 
ATOM   2871 O  OD1 . ASP A 1 379 ? 44.98709  18.09955  -27.63466 1.000 82.74820  ? 379 ASP A OD1 1 
ATOM   2872 O  OD2 . ASP A 1 379 ? 43.31264  17.40372  -28.87614 1.000 86.34748  ? 379 ASP A OD2 1 
ATOM   2873 N  N   . ALA A 1 380 ? 43.98916  13.34991  -25.58607 1.000 61.79233  ? 380 ALA A N   1 
ATOM   2874 C  CA  . ALA A 1 380 ? 43.69072  12.41536  -24.50506 1.000 59.34608  ? 380 ALA A CA  1 
ATOM   2875 C  C   . ALA A 1 380 ? 44.96551  11.80828  -23.93163 1.000 62.73178  ? 380 ALA A C   1 
ATOM   2876 O  O   . ALA A 1 380 ? 45.06930  11.59471  -22.71789 1.000 63.82016  ? 380 ALA A O   1 
ATOM   2877 C  CB  . ALA A 1 380 ? 42.74506  11.32122  -24.99938 1.000 54.30664  ? 380 ALA A CB  1 
ATOM   2878 N  N   . LEU A 1 381 ? 45.94527  11.51563  -24.79064 1.000 69.90576  ? 381 LEU A N   1 
ATOM   2879 C  CA  . LEU A 1 381 ? 47.20653  10.96092  -24.30966 1.000 70.23650  ? 381 LEU A CA  1 
ATOM   2880 C  C   . LEU A 1 381 ? 48.01704  11.99117  -23.53336 1.000 75.83839  ? 381 LEU A C   1 
ATOM   2881 O  O   . LEU A 1 381 ? 48.72930  11.63205  -22.58798 1.000 67.26758  ? 381 LEU A O   1 
ATOM   2882 C  CB  . LEU A 1 381 ? 48.02557  10.41140  -25.47757 1.000 67.97855  ? 381 LEU A CB  1 
ATOM   2883 C  CG  . LEU A 1 381 ? 47.65463  9.01498   -25.98129 1.000 66.96974  ? 381 LEU A CG  1 
ATOM   2884 C  CD1 . LEU A 1 381 ? 48.48585  8.63947   -27.19637 1.000 66.47125  ? 381 LEU A CD1 1 
ATOM   2885 C  CD2 . LEU A 1 381 ? 47.84954  7.99864   -24.87128 1.000 60.92962  ? 381 LEU A CD2 1 
ATOM   2886 N  N   . LEU A 1 382 ? 47.93226  13.26750  -23.91602 1.000 80.18339  ? 382 LEU A N   1 
ATOM   2887 C  CA  . LEU A 1 382 ? 48.66899  14.30487  -23.20278 1.000 70.52008  ? 382 LEU A CA  1 
ATOM   2888 C  C   . LEU A 1 382 ? 47.94390  14.75989  -21.94623 1.000 63.33268  ? 382 LEU A C   1 
ATOM   2889 O  O   . LEU A 1 382 ? 48.58958  15.20903  -20.99295 1.000 65.47811  ? 382 LEU A O   1 
ATOM   2890 C  CB  . LEU A 1 382 ? 48.92770  15.49611  -24.12247 1.000 61.11984  ? 382 LEU A CB  1 
ATOM   2891 C  CG  . LEU A 1 382 ? 49.94405  15.21793  -25.22864 1.000 60.26209  ? 382 LEU A CG  1 
ATOM   2892 C  CD1 . LEU A 1 382 ? 50.27858  16.49955  -25.95110 1.000 72.52484  ? 382 LEU A CD1 1 
ATOM   2893 C  CD2 . LEU A 1 382 ? 51.19740  14.57125  -24.65909 1.000 62.44136  ? 382 LEU A CD2 1 
ATOM   2894 N  N   . LEU A 1 383 ? 46.61775  14.65492  -21.92309 1.000 60.24236  ? 383 LEU A N   1 
ATOM   2895 C  CA  . LEU A 1 383 ? 45.86033  14.88544  -20.70163 1.000 61.30388  ? 383 LEU A CA  1 
ATOM   2896 C  C   . LEU A 1 383 ? 45.91815  13.69014  -19.76261 1.000 63.69906  ? 383 LEU A C   1 
ATOM   2897 O  O   . LEU A 1 383 ? 45.24004  13.69946  -18.73019 1.000 64.24037  ? 383 LEU A O   1 
ATOM   2898 C  CB  . LEU A 1 383 ? 44.40355  15.22769  -21.03571 1.000 55.72292  ? 383 LEU A CB  1 
ATOM   2899 C  CG  . LEU A 1 383 ? 44.18831  16.59183  -21.70231 1.000 61.41368  ? 383 LEU A CG  1 
ATOM   2900 C  CD1 . LEU A 1 383 ? 42.75520  16.75053  -22.18440 1.000 66.14488  ? 383 LEU A CD1 1 
ATOM   2901 C  CD2 . LEU A 1 383 ? 44.56418  17.71833  -20.75019 1.000 76.32157  ? 383 LEU A CD2 1 
ATOM   2902 N  N   . ASN A 1 384 ? 46.69350  12.66300  -20.11676 1.000 65.81148  ? 384 ASN A N   1 
ATOM   2903 C  CA  . ASN A 1 384 ? 46.96109  11.50886  -19.26060 1.000 68.10418  ? 384 ASN A CA  1 
ATOM   2904 C  C   . ASN A 1 384 ? 45.67955  10.74851  -18.91407 1.000 64.29084  ? 384 ASN A C   1 
ATOM   2905 O  O   . ASN A 1 384 ? 45.33479  10.54861  -17.74669 1.000 71.70826  ? 384 ASN A O   1 
ATOM   2906 C  CB  . ASN A 1 384 ? 47.71414  11.93950  -18.00074 1.000 76.95631  ? 384 ASN A CB  1 
ATOM   2907 C  CG  . ASN A 1 384 ? 49.13742  12.33599  -18.30146 1.000 91.16773  ? 384 ASN A CG  1 
ATOM   2908 O  OD1 . ASN A 1 384 ? 49.39378  13.42129  -18.82339 1.000 96.33251  ? 384 ASN A OD1 1 
ATOM   2909 N  ND2 . ASN A 1 384 ? 50.07753  11.45672  -17.97624 1.000 108.60688 ? 384 ASN A ND2 1 
ATOM   2910 N  N   . THR A 1 385 ? 44.98324  10.31225  -19.95990 1.000 60.64811  ? 385 THR A N   1 
ATOM   2911 C  CA  . THR A 1 385 ? 43.79998  9.48652   -19.77878 1.000 60.74037  ? 385 THR A CA  1 
ATOM   2912 C  C   . THR A 1 385 ? 44.18772  8.10127   -19.27079 1.000 57.67493  ? 385 THR A C   1 
ATOM   2913 O  O   . THR A 1 385 ? 45.29880  7.61767   -19.50186 1.000 57.26086  ? 385 THR A O   1 
ATOM   2914 C  CB  . THR A 1 385 ? 43.02060  9.36331   -21.09287 1.000 58.86385  ? 385 THR A CB  1 
ATOM   2915 O  OG1 . THR A 1 385 ? 41.80999  8.63542   -20.86148 1.000 65.02484  ? 385 THR A OG1 1 
ATOM   2916 C  CG2 . THR A 1 385 ? 43.84219  8.63319   -22.14947 1.000 62.49043  ? 385 THR A CG2 1 
ATOM   2917 N  N   . THR A 1 386 ? 43.26030  7.46911   -18.55007 1.000 58.67119  ? 386 THR A N   1 
ATOM   2918 C  CA  . THR A 1 386 ? 43.49484  6.13321   -18.01530 1.000 59.42970  ? 386 THR A CA  1 
ATOM   2919 C  C   . THR A 1 386 ? 43.04366  5.05255   -18.98891 1.000 70.16727  ? 386 THR A C   1 
ATOM   2920 O  O   . THR A 1 386 ? 43.69598  4.00772   -19.10057 1.000 79.54491  ? 386 THR A O   1 
ATOM   2921 C  CB  . THR A 1 386 ? 42.78476  5.96873   -16.66945 1.000 54.08921  ? 386 THR A CB  1 
ATOM   2922 O  OG1 . THR A 1 386 ? 42.99160  7.14310   -15.87314 1.000 65.41995  ? 386 THR A OG1 1 
ATOM   2923 C  CG2 . THR A 1 386 ? 43.33013  4.76271   -15.91259 1.000 50.42312  ? 386 THR A CG2 1 
ATOM   2924 N  N   . ARG A 1 387 ? 41.94387  5.29175   -19.70049 1.000 76.08875  ? 387 ARG A N   1 
ATOM   2925 C  CA  . ARG A 1 387 ? 41.47452  4.40885   -20.75661 1.000 66.14323  ? 387 ARG A CA  1 
ATOM   2926 C  C   . ARG A 1 387 ? 40.88327  5.25357   -21.87580 1.000 70.68075  ? 387 ARG A C   1 
ATOM   2927 O  O   . ARG A 1 387 ? 40.43014  6.37840   -21.65189 1.000 75.67824  ? 387 ARG A O   1 
ATOM   2928 C  CB  . ARG A 1 387 ? 40.42901  3.40285   -20.25475 1.000 57.26929  ? 387 ARG A CB  1 
ATOM   2929 C  CG  . ARG A 1 387 ? 40.97095  2.31952   -19.34114 1.000 63.48600  ? 387 ARG A CG  1 
ATOM   2930 C  CD  . ARG A 1 387 ? 39.97557  1.18434   -19.22778 1.000 67.13408  ? 387 ARG A CD  1 
ATOM   2931 N  NE  . ARG A 1 387 ? 38.63451  1.67075   -18.92071 1.000 69.68537  ? 387 ARG A NE  1 
ATOM   2932 C  CZ  . ARG A 1 387 ? 38.18436  1.90596   -17.69660 1.000 78.27824  ? 387 ARG A CZ  1 
ATOM   2933 N  NH1 . ARG A 1 387 ? 38.94680  1.71602   -16.63168 1.000 66.10999  ? 387 ARG A NH1 1 
ATOM   2934 N  NH2 . ARG A 1 387 ? 36.94042  2.34416   -17.53814 1.000 83.82994  ? 387 ARG A NH2 1 
ATOM   2935 N  N   . VAL A 1 388 ? 40.88867  4.69831   -23.08407 1.000 58.84090  ? 388 VAL A N   1 
ATOM   2936 C  CA  . VAL A 1 388 ? 40.34773  5.35395   -24.26817 1.000 68.33708  ? 388 VAL A CA  1 
ATOM   2937 C  C   . VAL A 1 388 ? 39.08523  4.61652   -24.68667 1.000 61.89844  ? 388 VAL A C   1 
ATOM   2938 O  O   . VAL A 1 388 ? 39.03258  3.38342   -24.63690 1.000 65.76594  ? 388 VAL A O   1 
ATOM   2939 C  CB  . VAL A 1 388 ? 41.37683  5.38026   -25.41633 1.000 63.64936  ? 388 VAL A CB  1 
ATOM   2940 C  CG1 . VAL A 1 388 ? 40.82919  6.13442   -26.61398 1.000 59.19613  ? 388 VAL A CG1 1 
ATOM   2941 C  CG2 . VAL A 1 388 ? 42.68348  5.99738   -24.94887 1.000 66.16786  ? 388 VAL A CG2 1 
ATOM   2942 N  N   . GLY A 1 389 ? 38.06523  5.37070   -25.08869 1.000 52.10797  ? 389 GLY A N   1 
ATOM   2943 C  CA  . GLY A 1 389 ? 36.81723  4.79425   -25.55467 1.000 52.57359  ? 389 GLY A CA  1 
ATOM   2944 C  C   . GLY A 1 389 ? 36.82530  4.65129   -27.06488 1.000 55.66624  ? 389 GLY A C   1 
ATOM   2945 O  O   . GLY A 1 389 ? 37.14487  5.59855   -27.78644 1.000 67.66417  ? 389 GLY A O   1 
ATOM   2946 N  N   . HIS A 1 390 ? 36.47059  3.44824   -27.52705 1.000 58.74667  ? 390 HIS A N   1 
ATOM   2947 C  CA  . HIS A 1 390 ? 36.40298  3.09032   -28.94178 1.000 64.30267  ? 390 HIS A CA  1 
ATOM   2948 C  C   . HIS A 1 390 ? 37.78309  3.07132   -29.59144 1.000 65.51293  ? 390 HIS A C   1 
ATOM   2949 O  O   . HIS A 1 390 ? 38.28742  1.99819   -29.93733 1.000 67.05292  ? 390 HIS A O   1 
ATOM   2950 C  CB  . HIS A 1 390 ? 35.45206  4.03076   -29.69341 1.000 56.17064  ? 390 HIS A CB  1 
ATOM   2951 C  CG  . HIS A 1 390 ? 34.04669  3.99584   -29.17832 1.000 54.85450  ? 390 HIS A CG  1 
ATOM   2952 N  ND1 . HIS A 1 390 ? 33.55038  4.93667   -28.30281 1.000 65.76574  ? 390 HIS A ND1 1 
ATOM   2953 C  CD2 . HIS A 1 390 ? 33.03679  3.12255   -29.40253 1.000 56.57339  ? 390 HIS A CD2 1 
ATOM   2954 C  CE1 . HIS A 1 390 ? 32.29243  4.65074   -28.01795 1.000 74.03405  ? 390 HIS A CE1 1 
ATOM   2955 N  NE2 . HIS A 1 390 ? 31.95638  3.55401   -28.67205 1.000 68.90585  ? 390 HIS A NE2 1 
ATOM   2956 N  N   . GLY A 1 391 ? 38.39566  4.23795   -29.77198 1.000 61.57317  ? 391 GLY A N   1 
ATOM   2957 C  CA  . GLY A 1 391 ? 39.74834  4.29881   -30.31703 1.000 57.91633  ? 391 GLY A CA  1 
ATOM   2958 C  C   . GLY A 1 391 ? 39.87051  3.72385   -31.71003 1.000 65.42781  ? 391 GLY A C   1 
ATOM   2959 O  O   . GLY A 1 391 ? 40.86988  3.06475   -32.02261 1.000 68.93715  ? 391 GLY A O   1 
ATOM   2960 N  N   . PHE A 1 392 ? 38.87198  3.96903   -32.56086 1.000 59.13638  ? 392 PHE A N   1 
ATOM   2961 C  CA  . PHE A 1 392 ? 38.81543  3.31013   -33.86019 1.000 48.80196  ? 392 PHE A CA  1 
ATOM   2962 C  C   . PHE A 1 392 ? 39.97245  3.71960   -34.76226 1.000 63.64751  ? 392 PHE A C   1 
ATOM   2963 O  O   . PHE A 1 392 ? 40.45315  2.90543   -35.55631 1.000 79.03739  ? 392 PHE A O   1 
ATOM   2964 C  CB  . PHE A 1 392 ? 37.47444  3.61279   -34.53081 1.000 57.44407  ? 392 PHE A CB  1 
ATOM   2965 C  CG  . PHE A 1 392 ? 37.04501  2.57982   -35.52896 1.000 67.65752  ? 392 PHE A CG  1 
ATOM   2966 C  CD1 . PHE A 1 392 ? 36.74193  1.29152   -35.12197 1.000 73.51083  ? 392 PHE A CD1 1 
ATOM   2967 C  CD2 . PHE A 1 392 ? 36.92556  2.90000   -36.87013 1.000 62.02147  ? 392 PHE A CD2 1 
ATOM   2968 C  CE1 . PHE A 1 392 ? 36.33958  0.33698   -36.03516 1.000 64.99197  ? 392 PHE A CE1 1 
ATOM   2969 C  CE2 . PHE A 1 392 ? 36.52204  1.95125   -37.78919 1.000 64.18494  ? 392 PHE A CE2 1 
ATOM   2970 C  CZ  . PHE A 1 392 ? 36.22854  0.66710   -37.37096 1.000 80.53304  ? 392 PHE A CZ  1 
ATOM   2971 N  N   . ALA A 1 393 ? 40.44556  4.96072   -34.65203 1.000 55.09924  ? 393 ALA A N   1 
ATOM   2972 C  CA  . ALA A 1 393 ? 41.47727  5.48030   -35.54353 1.000 54.29662  ? 393 ALA A CA  1 
ATOM   2973 C  C   . ALA A 1 393 ? 42.85400  5.52919   -34.88553 1.000 65.10573  ? 393 ALA A C   1 
ATOM   2974 O  O   . ALA A 1 393 ? 43.70337  6.33579   -35.28250 1.000 65.53099  ? 393 ALA A O   1 
ATOM   2975 C  CB  . ALA A 1 393 ? 41.08773  6.86619   -36.05822 1.000 56.50250  ? 393 ALA A CB  1 
ATOM   2976 N  N   . LEU A 1 394 ? 43.09764  4.67522   -33.88946 1.000 68.95935  ? 394 LEU A N   1 
ATOM   2977 C  CA  . LEU A 1 394 ? 44.42908  4.60599   -33.29723 1.000 65.58731  ? 394 LEU A CA  1 
ATOM   2978 C  C   . LEU A 1 394 ? 45.41221  3.90240   -34.22222 1.000 64.25926  ? 394 LEU A C   1 
ATOM   2979 O  O   . LEU A 1 394 ? 46.56938  4.31796   -34.32696 1.000 63.80125  ? 394 LEU A O   1 
ATOM   2980 C  CB  . LEU A 1 394 ? 44.36983  3.89564   -31.93807 1.000 55.27617  ? 394 LEU A CB  1 
ATOM   2981 C  CG  . LEU A 1 394 ? 45.69622  3.66342   -31.20805 1.000 62.39728  ? 394 LEU A CG  1 
ATOM   2982 C  CD1 . LEU A 1 394 ? 46.35213  4.97113   -30.77977 1.000 53.84829  ? 394 LEU A CD1 1 
ATOM   2983 C  CD2 . LEU A 1 394 ? 45.49664  2.74268   -30.00949 1.000 70.65275  ? 394 LEU A CD2 1 
ATOM   2984 N  N   . ILE A 1 395 ? 44.95900  2.85531   -34.91794 1.000 63.54852  ? 395 ILE A N   1 
ATOM   2985 C  CA  . ILE A 1 395 ? 45.82954  2.08984   -35.80361 1.000 59.90395  ? 395 ILE A CA  1 
ATOM   2986 C  C   . ILE A 1 395 ? 46.35691  2.94706   -36.94609 1.000 67.52621  ? 395 ILE A C   1 
ATOM   2987 O  O   . ILE A 1 395 ? 47.40765  2.63802   -37.51885 1.000 76.36226  ? 395 ILE A O   1 
ATOM   2988 C  CB  . ILE A 1 395 ? 45.08529  0.84075   -36.32709 1.000 53.74319  ? 395 ILE A CB  1 
ATOM   2989 C  CG1 . ILE A 1 395 ? 46.06875  -0.16914  -36.92416 1.000 60.44496  ? 395 ILE A CG1 1 
ATOM   2990 C  CG2 . ILE A 1 395 ? 44.01287  1.22693   -37.34263 1.000 64.32467  ? 395 ILE A CG2 1 
ATOM   2991 C  CD1 . ILE A 1 395 ? 47.06384  -0.71805  -35.92989 1.000 75.49574  ? 395 ILE A CD1 1 
ATOM   2992 N  N   . LYS A 1 396 ? 45.66040  4.03273   -37.28410 1.000 60.78002  ? 396 LYS A N   1 
ATOM   2993 C  CA  . LYS A 1 396 ? 46.09593  4.92615   -38.34951 1.000 61.60474  ? 396 LYS A CA  1 
ATOM   2994 C  C   . LYS A 1 396 ? 47.25069  5.82950   -37.93792 1.000 60.36788  ? 396 LYS A C   1 
ATOM   2995 O  O   . LYS A 1 396 ? 47.82648  6.49991   -38.80202 1.000 73.95432  ? 396 LYS A O   1 
ATOM   2996 C  CB  . LYS A 1 396 ? 44.92325  5.79471   -38.81420 1.000 62.72679  ? 396 LYS A CB  1 
ATOM   2997 C  CG  . LYS A 1 396 ? 43.69030  5.01560   -39.22291 1.000 65.19724  ? 396 LYS A CG  1 
ATOM   2998 C  CD  . LYS A 1 396 ? 42.63364  5.94718   -39.78873 1.000 59.54182  ? 396 LYS A CD  1 
ATOM   2999 C  CE  . LYS A 1 396 ? 41.33764  5.20631   -40.06043 1.000 68.07680  ? 396 LYS A CE  1 
ATOM   3000 N  NZ  . LYS A 1 396 ? 40.31146  6.09977   -40.65475 1.000 65.83021  ? 396 LYS A NZ  1 
ATOM   3001 N  N   . HIS A 1 397 ? 47.59713  5.87076   -36.65410 1.000 59.46322  ? 397 HIS A N   1 
ATOM   3002 C  CA  . HIS A 1 397 ? 48.65701  6.74616   -36.15110 1.000 64.16521  ? 397 HIS A CA  1 
ATOM   3003 C  C   . HIS A 1 397 ? 49.75465  5.92286   -35.49459 1.000 65.70737  ? 397 HIS A C   1 
ATOM   3004 O  O   . HIS A 1 397 ? 49.60207  5.49456   -34.33708 1.000 67.61169  ? 397 HIS A O   1 
ATOM   3005 C  CB  . HIS A 1 397 ? 48.09065  7.76762   -35.16685 1.000 53.90731  ? 397 HIS A CB  1 
ATOM   3006 C  CG  . HIS A 1 397 ? 47.32910  8.87610   -35.82138 1.000 63.30681  ? 397 HIS A CG  1 
ATOM   3007 N  ND1 . HIS A 1 397 ? 47.92311  10.05454  -36.21511 1.000 77.12808  ? 397 HIS A ND1 1 
ATOM   3008 C  CD2 . HIS A 1 397 ? 46.02237  8.98533   -36.15478 1.000 58.72108  ? 397 HIS A CD2 1 
ATOM   3009 C  CE1 . HIS A 1 397 ? 47.01577  10.84262  -36.76214 1.000 81.95266  ? 397 HIS A CE1 1 
ATOM   3010 N  NE2 . HIS A 1 397 ? 45.85385  10.21794  -36.73629 1.000 73.11328  ? 397 HIS A NE2 1 
ATOM   3011 N  N   . PRO A 1 398 ? 50.88354  5.69486   -36.17935 1.000 67.18408  ? 398 PRO A N   1 
ATOM   3012 C  CA  . PRO A 1 398 ? 51.93206  4.81705   -35.63599 1.000 67.14128  ? 398 PRO A CA  1 
ATOM   3013 C  C   . PRO A 1 398 ? 52.44089  5.21885   -34.25810 1.000 77.32585  ? 398 PRO A C   1 
ATOM   3014 O  O   . PRO A 1 398 ? 52.35372  4.43039   -33.31050 1.000 82.63314  ? 398 PRO A O   1 
ATOM   3015 C  CB  . PRO A 1 398 ? 53.04642  4.92574   -36.68412 1.000 69.85420  ? 398 PRO A CB  1 
ATOM   3016 C  CG  . PRO A 1 398 ? 52.34242  5.30652   -37.94340 1.000 76.28612  ? 398 PRO A CG  1 
ATOM   3017 C  CD  . PRO A 1 398 ? 51.22284  6.20498   -37.51787 1.000 69.48645  ? 398 PRO A CD  1 
ATOM   3018 N  N   . ARG A 1 399 ? 52.96809  6.44111   -34.13562 1.000 77.11760  ? 399 ARG A N   1 
ATOM   3019 C  CA  . ARG A 1 399 ? 53.55024  6.88432   -32.87038 1.000 82.46203  ? 399 ARG A CA  1 
ATOM   3020 C  C   . ARG A 1 399 ? 52.50491  6.96478   -31.76327 1.000 74.13264  ? 399 ARG A C   1 
ATOM   3021 O  O   . ARG A 1 399 ? 52.78424  6.59383   -30.61713 1.000 73.46016  ? 399 ARG A O   1 
ATOM   3022 C  CB  . ARG A 1 399 ? 54.23849  8.23850   -33.04954 1.000 81.03216  ? 399 ARG A CB  1 
ATOM   3023 C  CG  . ARG A 1 399 ? 54.79499  8.83588   -31.75890 1.000 82.92834  ? 399 ARG A CG  1 
ATOM   3024 C  CD  . ARG A 1 399 ? 55.84895  7.92842   -31.13201 1.000 93.46107  ? 399 ARG A CD  1 
ATOM   3025 N  NE  . ARG A 1 399 ? 56.53025  8.58113   -30.01691 1.000 97.97088  ? 399 ARG A NE  1 
ATOM   3026 C  CZ  . ARG A 1 399 ? 56.41828  8.21961   -28.74621 1.000 102.50358 ? 399 ARG A CZ  1 
ATOM   3027 N  NH1 . ARG A 1 399 ? 55.70326  7.16573   -28.38677 1.000 98.21307  ? 399 ARG A NH1 1 
ATOM   3028 N  NH2 . ARG A 1 399 ? 57.04572  8.92916   -27.81365 1.000 99.51858  ? 399 ARG A NH2 1 
ATOM   3029 N  N   . PHE A 1 400 ? 51.30375  7.46217   -32.07609 1.000 71.45165  ? 400 PHE A N   1 
ATOM   3030 C  CA  . PHE A 1 400 ? 50.25031  7.51080   -31.06465 1.000 71.04123  ? 400 PHE A CA  1 
ATOM   3031 C  C   . PHE A 1 400 ? 49.97595  6.12140   -30.50753 1.000 68.29100  ? 400 PHE A C   1 
ATOM   3032 O  O   . PHE A 1 400 ? 49.77421  5.95407   -29.29863 1.000 78.31203  ? 400 PHE A O   1 
ATOM   3033 C  CB  . PHE A 1 400 ? 48.96064  8.10108   -31.64269 1.000 73.53690  ? 400 PHE A CB  1 
ATOM   3034 C  CG  . PHE A 1 400 ? 49.04884  9.56032   -32.01767 1.000 56.44630  ? 400 PHE A CG  1 
ATOM   3035 C  CD1 . PHE A 1 400 ? 50.21411  10.28788  -31.82812 1.000 62.45540  ? 400 PHE A CD1 1 
ATOM   3036 C  CD2 . PHE A 1 400 ? 47.94706  10.20428  -32.55740 1.000 58.90646  ? 400 PHE A CD2 1 
ATOM   3037 C  CE1 . PHE A 1 400 ? 50.27820  11.62403  -32.17976 1.000 72.34472  ? 400 PHE A CE1 1 
ATOM   3038 C  CE2 . PHE A 1 400 ? 48.00504  11.53790  -32.90886 1.000 63.71487  ? 400 PHE A CE2 1 
ATOM   3039 C  CZ  . PHE A 1 400 ? 49.17224  12.24891  -32.71931 1.000 76.36001  ? 400 PHE A CZ  1 
ATOM   3040 N  N   . THR A 1 401 ? 49.95789  5.11318   -31.38171 1.000 74.23163  ? 401 THR A N   1 
ATOM   3041 C  CA  . THR A 1 401 ? 49.75498  3.73799   -30.93791 1.000 79.80663  ? 401 THR A CA  1 
ATOM   3042 C  C   . THR A 1 401 ? 50.86717  3.29522   -29.99769 1.000 72.50382  ? 401 THR A C   1 
ATOM   3043 O  O   . THR A 1 401 ? 50.60684  2.70179   -28.94555 1.000 75.16228  ? 401 THR A O   1 
ATOM   3044 C  CB  . THR A 1 401 ? 49.68125  2.80196   -32.14571 1.000 74.98639  ? 401 THR A CB  1 
ATOM   3045 O  OG1 . THR A 1 401 ? 48.71460  3.29439   -33.07771 1.000 64.38037  ? 401 THR A OG1 1 
ATOM   3046 C  CG2 . THR A 1 401 ? 49.27662  1.40610   -31.71523 1.000 82.29806  ? 401 THR A CG2 1 
ATOM   3047 N  N   . GLU A 1 402 ? 52.11979  3.56586   -30.36890 1.000 74.88840  ? 402 GLU A N   1 
ATOM   3048 C  CA  . GLU A 1 402 ? 53.24231  3.16575   -29.52733 1.000 84.05290  ? 402 GLU A CA  1 
ATOM   3049 C  C   . GLU A 1 402 ? 53.14955  3.80668   -28.14831 1.000 87.48904  ? 402 GLU A C   1 
ATOM   3050 O  O   . GLU A 1 402 ? 53.29933  3.12900   -27.12487 1.000 80.53354  ? 402 GLU A O   1 
ATOM   3051 C  CB  . GLU A 1 402 ? 54.56312  3.53969   -30.19885 1.000 78.18553  ? 402 GLU A CB  1 
ATOM   3052 C  CG  . GLU A 1 402 ? 54.71554  3.03260   -31.62025 1.000 76.99416  ? 402 GLU A CG  1 
ATOM   3053 C  CD  . GLU A 1 402 ? 56.00827  3.49702   -32.26001 1.000 96.31765  ? 402 GLU A CD  1 
ATOM   3054 O  OE1 . GLU A 1 402 ? 56.75018  4.26283   -31.60919 1.000 97.66096  ? 402 GLU A OE1 1 
ATOM   3055 O  OE2 . GLU A 1 402 ? 56.28303  3.09417   -33.41000 1.000 106.04937 ? 402 GLU A OE2 1 
ATOM   3056 N  N   . LEU A 1 403 ? 52.88470  5.11538   -28.10469 1.000 76.85967  ? 403 LEU A N   1 
ATOM   3057 C  CA  . LEU A 1 403 ? 52.90072  5.84408   -26.83877 1.000 77.54281  ? 403 LEU A CA  1 
ATOM   3058 C  C   . LEU A 1 403 ? 51.85781  5.30687   -25.86707 1.000 79.99036  ? 403 LEU A C   1 
ATOM   3059 O  O   . LEU A 1 403 ? 52.13458  5.14397   -24.67267 1.000 85.65602  ? 403 LEU A O   1 
ATOM   3060 C  CB  . LEU A 1 403 ? 52.67204  7.33273   -27.08844 1.000 62.37652  ? 403 LEU A CB  1 
ATOM   3061 C  CG  . LEU A 1 403 ? 52.74762  8.21745   -25.84470 1.000 71.06333  ? 403 LEU A CG  1 
ATOM   3062 C  CD1 . LEU A 1 403 ? 54.15240  8.20092   -25.25820 1.000 82.83356  ? 403 LEU A CD1 1 
ATOM   3063 C  CD2 . LEU A 1 403 ? 52.31477  9.63054   -26.18502 1.000 88.06260  ? 403 LEU A CD2 1 
ATOM   3064 N  N   . ALA A 1 404 ? 50.64459  5.04095   -26.35743 1.000 71.07062  ? 404 ALA A N   1 
ATOM   3065 C  CA  . ALA A 1 404 ? 49.59403  4.53889   -25.47772 1.000 70.33684  ? 404 ALA A CA  1 
ATOM   3066 C  C   . ALA A 1 404 ? 49.99118  3.20655   -24.85601 1.000 76.48527  ? 404 ALA A C   1 
ATOM   3067 O  O   . ALA A 1 404 ? 49.68947  2.94068   -23.68640 1.000 75.20183  ? 404 ALA A O   1 
ATOM   3068 C  CB  . ALA A 1 404 ? 48.28186  4.40880   -26.24765 1.000 59.52137  ? 404 ALA A CB  1 
ATOM   3069 N  N   . LYS A 1 405 ? 50.66609  2.35476   -25.62830 1.000 70.98935  ? 405 LYS A N   1 
ATOM   3070 C  CA  . LYS A 1 405 ? 51.18287  1.10326   -25.08627 1.000 71.33664  ? 405 LYS A CA  1 
ATOM   3071 C  C   . LYS A 1 405 ? 52.24039  1.36039   -24.01887 1.000 76.06677  ? 405 LYS A C   1 
ATOM   3072 O  O   . LYS A 1 405 ? 52.22770  0.73585   -22.95109 1.000 82.06721  ? 405 LYS A O   1 
ATOM   3073 C  CB  . LYS A 1 405 ? 51.75623  0.25432   -26.21893 1.000 72.59488  ? 405 LYS A CB  1 
ATOM   3074 C  CG  . LYS A 1 405 ? 51.74314  -1.24037  -25.96554 1.000 71.36223  ? 405 LYS A CG  1 
ATOM   3075 C  CD  . LYS A 1 405 ? 52.09296  -1.97723  -27.24328 1.000 66.95895  ? 405 LYS A CD  1 
ATOM   3076 C  CE  . LYS A 1 405 ? 51.76380  -3.45059  -27.15612 1.000 80.32886  ? 405 LYS A CE  1 
ATOM   3077 N  NZ  . LYS A 1 405 ? 51.77407  -4.05439  -28.51379 1.000 76.60828  ? 405 LYS A NZ  1 
ATOM   3078 N  N   . GLU A 1 406 ? 53.16952  2.28077   -24.29482 1.000 74.97401  ? 406 GLU A N   1 
ATOM   3079 C  CA  . GLU A 1 406 ? 54.24822  2.55971   -23.34992 1.000 60.62739  ? 406 GLU A CA  1 
ATOM   3080 C  C   . GLU A 1 406 ? 53.70254  3.06925   -22.02257 1.000 71.34146  ? 406 GLU A C   1 
ATOM   3081 O  O   . GLU A 1 406 ? 54.17437  2.66542   -20.95320 1.000 73.14863  ? 406 GLU A O   1 
ATOM   3082 C  CB  . GLU A 1 406 ? 55.22036  3.57829   -23.94923 1.000 81.90292  ? 406 GLU A CB  1 
ATOM   3083 C  CG  . GLU A 1 406 ? 55.79334  3.19169   -25.30261 1.000 94.66142  ? 406 GLU A CG  1 
ATOM   3084 C  CD  . GLU A 1 406 ? 56.41301  4.37311   -26.02941 1.000 96.17832  ? 406 GLU A CD  1 
ATOM   3085 O  OE1 . GLU A 1 406 ? 56.64504  5.41891   -25.38543 1.000 90.63912  ? 406 GLU A OE1 1 
ATOM   3086 O  OE2 . GLU A 1 406 ? 56.66400  4.25659   -27.24699 1.000 91.38578  ? 406 GLU A OE2 1 
ATOM   3087 N  N   . ASN A 1 407 ? 52.70999  3.95799   -22.07091 1.000 83.32272  ? 407 ASN A N   1 
ATOM   3088 C  CA  . ASN A 1 407 ? 52.13035  4.51424   -20.85614 1.000 77.33469  ? 407 ASN A CA  1 
ATOM   3089 C  C   . ASN A 1 407 ? 51.12556  3.57828   -20.19909 1.000 75.88224  ? 407 ASN A C   1 
ATOM   3090 O  O   . ASN A 1 407 ? 50.79268  3.77615   -19.02486 1.000 79.51723  ? 407 ASN A O   1 
ATOM   3091 C  CB  . ASN A 1 407 ? 51.46126  5.85714   -21.16034 1.000 72.21333  ? 407 ASN A CB  1 
ATOM   3092 C  CG  . ASN A 1 407 ? 52.44303  6.89768   -21.66582 1.000 84.39522  ? 407 ASN A CG  1 
ATOM   3093 O  OD1 . ASN A 1 407 ? 53.63747  6.62847   -21.79701 1.000 84.97992  ? 407 ASN A OD1 1 
ATOM   3094 N  ND2 . ASN A 1 407 ? 51.94187  8.09149   -21.96035 1.000 74.99038  ? 407 ASN A ND2 1 
ATOM   3095 N  N   . GLY A 1 408 ? 50.64287  2.56980   -20.91947 1.000 66.80420  ? 408 GLY A N   1 
ATOM   3096 C  CA  . GLY A 1 408 ? 49.70811  1.61572   -20.35784 1.000 63.70709  ? 408 GLY A CA  1 
ATOM   3097 C  C   . GLY A 1 408 ? 48.24357  1.93614   -20.55172 1.000 62.74673  ? 408 GLY A C   1 
ATOM   3098 O  O   . GLY A 1 408 ? 47.40799  1.39350   -19.82103 1.000 67.37408  ? 408 GLY A O   1 
ATOM   3099 N  N   . VAL A 1 409 ? 47.90148  2.79726   -21.50451 1.000 65.80773  ? 409 VAL A N   1 
ATOM   3100 C  CA  . VAL A 1 409 ? 46.51025  3.17275   -21.73472 1.000 70.12638  ? 409 VAL A CA  1 
ATOM   3101 C  C   . VAL A 1 409 ? 45.82057  2.07458   -22.53405 1.000 66.08950  ? 409 VAL A C   1 
ATOM   3102 O  O   . VAL A 1 409 ? 46.30197  1.66699   -23.59735 1.000 71.47754  ? 409 VAL A O   1 
ATOM   3103 C  CB  . VAL A 1 409 ? 46.42512  4.52483   -22.46093 1.000 56.15988  ? 409 VAL A CB  1 
ATOM   3104 C  CG1 . VAL A 1 409 ? 45.02454  5.10563   -22.33905 1.000 51.03212  ? 409 VAL A CG1 1 
ATOM   3105 C  CG2 . VAL A 1 409 ? 47.46576  5.48988   -21.91407 1.000 54.14652  ? 409 VAL A CG2 1 
ATOM   3106 N  N   . ALA A 1 410 ? 44.68783  1.59662   -22.02758 1.000 54.93757  ? 410 ALA A N   1 
ATOM   3107 C  CA  . ALA A 1 410 ? 43.92871  0.53084   -22.66535 1.000 50.27564  ? 410 ALA A CA  1 
ATOM   3108 C  C   . ALA A 1 410 ? 42.72969  1.10196   -23.41450 1.000 58.85880  ? 410 ALA A C   1 
ATOM   3109 O  O   . ALA A 1 410 ? 42.19627  2.15434   -23.05721 1.000 75.89801  ? 410 ALA A O   1 
ATOM   3110 C  CB  . ALA A 1 410 ? 43.45644  -0.49471  -21.63227 1.000 65.33343  ? 410 ALA A CB  1 
ATOM   3111 N  N   . VAL A 1 411 ? 42.30804  0.39401   -24.46016 1.000 60.50369  ? 411 VAL A N   1 
ATOM   3112 C  CA  . VAL A 1 411 ? 41.21087  0.82715   -25.31807 1.000 55.02506  ? 411 VAL A CA  1 
ATOM   3113 C  C   . VAL A 1 411 ? 39.97850  -0.01574  -25.01461 1.000 67.54931  ? 411 VAL A C   1 
ATOM   3114 O  O   . VAL A 1 411 ? 40.06038  -1.24874  -24.93752 1.000 61.58731  ? 411 VAL A O   1 
ATOM   3115 C  CB  . VAL A 1 411 ? 41.59118  0.72371   -26.80442 1.000 46.88826  ? 411 VAL A CB  1 
ATOM   3116 C  CG1 . VAL A 1 411 ? 40.53711  1.39108   -27.66940 1.000 64.15345  ? 411 VAL A CG1 1 
ATOM   3117 C  CG2 . VAL A 1 411 ? 42.95996  1.34186   -27.05094 1.000 44.55234  ? 411 VAL A CG2 1 
ATOM   3118 N  N   . GLU A 1 412 ? 38.83720  0.64858   -24.83897 1.000 66.79671  ? 412 GLU A N   1 
ATOM   3119 C  CA  . GLU A 1 412 ? 37.55811  -0.02117  -24.61932 1.000 64.71073  ? 412 GLU A CA  1 
ATOM   3120 C  C   . GLU A 1 412 ? 36.92817  -0.26653  -25.98275 1.000 69.22734  ? 412 GLU A C   1 
ATOM   3121 O  O   . GLU A 1 412 ? 36.42632  0.66151   -26.62269 1.000 69.59864  ? 412 GLU A O   1 
ATOM   3122 C  CB  . GLU A 1 412 ? 36.65122  0.82627   -23.73072 1.000 60.78916  ? 412 GLU A CB  1 
ATOM   3123 C  CG  . GLU A 1 412 ? 37.27903  1.27309   -22.41936 1.000 71.57655  ? 412 GLU A CG  1 
ATOM   3124 C  CD  . GLU A 1 412 ? 36.58292  2.48824   -21.83076 1.000 75.17504  ? 412 GLU A CD  1 
ATOM   3125 O  OE1 . GLU A 1 412 ? 36.01334  3.28123   -22.60992 1.000 73.12215  ? 412 GLU A OE1 1 
ATOM   3126 O  OE2 . GLU A 1 412 ? 36.60182  2.65377   -20.59302 1.000 70.71316  ? 412 GLU A OE2 1 
ATOM   3127 N  N   . VAL A 1 413 ? 36.95092  -1.51788  -26.43140 1.000 69.39504  ? 413 VAL A N   1 
ATOM   3128 C  CA  . VAL A 1 413 ? 36.44043  -1.87780  -27.74788 1.000 59.68810  ? 413 VAL A CA  1 
ATOM   3129 C  C   . VAL A 1 413 ? 35.00168  -2.35501  -27.59310 1.000 58.59222  ? 413 VAL A C   1 
ATOM   3130 O  O   . VAL A 1 413 ? 34.73502  -3.33284  -26.88679 1.000 67.87033  ? 413 VAL A O   1 
ATOM   3131 C  CB  . VAL A 1 413 ? 37.31651  -2.95633  -28.40353 1.000 55.27499  ? 413 VAL A CB  1 
ATOM   3132 C  CG1 . VAL A 1 413 ? 37.07238  -2.99917  -29.90644 1.000 46.35356  ? 413 VAL A CG1 1 
ATOM   3133 C  CG2 . VAL A 1 413 ? 38.79045  -2.70808  -28.09599 1.000 52.08344  ? 413 VAL A CG2 1 
ATOM   3134 N  N   . ASN A 1 414 ? 34.07458  -1.66163  -28.25399 1.000 61.70520  ? 414 ASN A N   1 
ATOM   3135 C  CA  . ASN A 1 414 ? 32.64555  -1.95670  -28.18918 1.000 67.75065  ? 414 ASN A CA  1 
ATOM   3136 C  C   . ASN A 1 414 ? 32.17739  -2.34059  -29.58730 1.000 71.25244  ? 414 ASN A C   1 
ATOM   3137 O  O   . ASN A 1 414 ? 31.80477  -1.47090  -30.38748 1.000 67.11076  ? 414 ASN A O   1 
ATOM   3138 C  CB  . ASN A 1 414 ? 31.87043  -0.76152  -27.64271 1.000 68.17090  ? 414 ASN A CB  1 
ATOM   3139 C  CG  . ASN A 1 414 ? 32.49059  -0.18758  -26.37409 1.000 60.48386  ? 414 ASN A CG  1 
ATOM   3140 O  OD1 . ASN A 1 414 ? 32.72609  -0.91075  -25.40553 1.000 65.09350  ? 414 ASN A OD1 1 
ATOM   3141 N  ND2 . ASN A 1 414 ? 32.76041  1.11412   -26.37888 1.000 72.83068  ? 414 ASN A ND2 1 
ATOM   3142 N  N   . PRO A 1 415 ? 32.15835  -3.64216  -29.91540 1.000 70.55132  ? 415 PRO A N   1 
ATOM   3143 C  CA  . PRO A 1 415 ? 31.94804  -4.06914  -31.30847 1.000 55.52119  ? 415 PRO A CA  1 
ATOM   3144 C  C   . PRO A 1 415 ? 30.56178  -3.79149  -31.87035 1.000 55.78866  ? 415 PRO A C   1 
ATOM   3145 O  O   . PRO A 1 415 ? 30.44910  -3.19214  -32.94430 1.000 59.05546  ? 415 PRO A O   1 
ATOM   3146 C  CB  . PRO A 1 415 ? 32.21736  -5.57805  -31.24760 1.000 68.17671  ? 415 PRO A CB  1 
ATOM   3147 C  CG  . PRO A 1 415 ? 33.01105  -5.78440  -29.99057 1.000 69.30495  ? 415 PRO A CG  1 
ATOM   3148 C  CD  . PRO A 1 415 ? 32.47673  -4.77402  -29.03246 1.000 72.15396  ? 415 PRO A CD  1 
ATOM   3149 N  N   . ILE A 1 416 ? 29.50605  -4.22221  -31.17234 1.000 56.62313  ? 416 ILE A N   1 
ATOM   3150 C  CA  . ILE A 1 416 ? 28.15873  -4.13183  -31.73598 1.000 53.17574  ? 416 ILE A CA  1 
ATOM   3151 C  C   . ILE A 1 416 ? 27.77737  -2.67917  -31.98623 1.000 64.15738  ? 416 ILE A C   1 
ATOM   3152 O  O   . ILE A 1 416 ? 27.14383  -2.35300  -32.99839 1.000 64.47146  ? 416 ILE A O   1 
ATOM   3153 C  CB  . ILE A 1 416 ? 27.13720  -4.83807  -30.82332 1.000 47.91220  ? 416 ILE A CB  1 
ATOM   3154 C  CG1 . ILE A 1 416 ? 27.47207  -6.32651  -30.69769 1.000 65.14772  ? 416 ILE A CG1 1 
ATOM   3155 C  CG2 . ILE A 1 416 ? 25.71398  -4.64700  -31.35167 1.000 48.20621  ? 416 ILE A CG2 1 
ATOM   3156 C  CD1 . ILE A 1 416 ? 26.39002  -7.14641  -30.01759 1.000 71.73756  ? 416 ILE A CD1 1 
ATOM   3157 N  N   . SER A 1 417 ? 28.15501  -1.78312  -31.07215 1.000 78.18332  ? 417 SER A N   1 
ATOM   3158 C  CA  . SER A 1 417 ? 27.87326  -0.36571  -31.27522 1.000 64.59638  ? 417 SER A CA  1 
ATOM   3159 C  C   . SER A 1 417 ? 28.57744  0.16243   -32.52121 1.000 51.70563  ? 417 SER A C   1 
ATOM   3160 O  O   . SER A 1 417 ? 27.98626  0.91666   -33.30056 1.000 60.91326  ? 417 SER A O   1 
ATOM   3161 C  CB  . SER A 1 417 ? 28.27721  0.42945   -30.03161 1.000 67.49735  ? 417 SER A CB  1 
ATOM   3162 O  OG  . SER A 1 417 ? 28.07122  1.82079   -30.20714 1.000 77.56066  ? 417 SER A OG  1 
ATOM   3163 N  N   . ASN A 1 418 ? 29.83326  -0.24202  -32.74008 1.000 51.54754  ? 418 ASN A N   1 
ATOM   3164 C  CA  . ASN A 1 418 ? 30.58879  0.24489   -33.89173 1.000 49.33302  ? 418 ASN A CA  1 
ATOM   3165 C  C   . ASN A 1 418 ? 29.97866  -0.18923  -35.21924 1.000 54.99467  ? 418 ASN A C   1 
ATOM   3166 O  O   . ASN A 1 418 ? 30.26128  0.43227   -36.24929 1.000 67.57699  ? 418 ASN A O   1 
ATOM   3167 C  CB  . ASN A 1 418 ? 32.04370  -0.22101  -33.80037 1.000 42.68216  ? 418 ASN A CB  1 
ATOM   3168 C  CG  . ASN A 1 418 ? 32.76555  0.36992   -32.60559 1.000 55.19046  ? 418 ASN A CG  1 
ATOM   3169 O  OD1 . ASN A 1 418 ? 32.16033  1.05053   -31.77826 1.000 64.76261  ? 418 ASN A OD1 1 
ATOM   3170 N  ND2 . ASN A 1 418 ? 34.06240  0.10678   -32.50370 1.000 52.48925  ? 418 ASN A ND2 1 
ATOM   3171 N  N   . GLN A 1 419 ? 29.15240  -1.23496  -35.22301 1.000 57.68254  ? 419 GLN A N   1 
ATOM   3172 C  CA  . GLN A 1 419 ? 28.45054  -1.64166  -36.43453 1.000 55.27401  ? 419 GLN A CA  1 
ATOM   3173 C  C   . GLN A 1 419 ? 27.14794  -0.86899  -36.62257 1.000 60.68125  ? 419 GLN A C   1 
ATOM   3174 O  O   . GLN A 1 419 ? 26.88603  -0.34324  -37.70905 1.000 73.68167  ? 419 GLN A O   1 
ATOM   3175 C  CB  . GLN A 1 419 ? 28.16918  -3.14669  -36.40589 1.000 40.83267  ? 419 GLN A CB  1 
ATOM   3176 C  CG  . GLN A 1 419 ? 27.48721  -3.66113  -37.66172 1.000 62.14335  ? 419 GLN A CG  1 
ATOM   3177 C  CD  . GLN A 1 419 ? 26.98484  -5.08331  -37.51888 1.000 70.04394  ? 419 GLN A CD  1 
ATOM   3178 O  OE1 . GLN A 1 419 ? 26.05589  -5.35532  -36.75728 1.000 67.40838  ? 419 GLN A OE1 1 
ATOM   3179 N  NE2 . GLN A 1 419 ? 27.59820  -6.00065  -38.25464 1.000 69.43324  ? 419 GLN A NE2 1 
ATOM   3180 N  N   . ILE A 1 420 ? 26.32403  -0.79414  -35.57352 1.000 54.09823  ? 420 ILE A N   1 
ATOM   3181 C  CA  . ILE A 1 420 ? 25.03727  -0.11029  -35.67988 1.000 45.94086  ? 420 ILE A CA  1 
ATOM   3182 C  C   . ILE A 1 420 ? 25.23829  1.38027   -35.92168 1.000 61.40952  ? 420 ILE A C   1 
ATOM   3183 O  O   . ILE A 1 420 ? 24.57135  1.98098   -36.77397 1.000 79.06791  ? 420 ILE A O   1 
ATOM   3184 C  CB  . ILE A 1 420 ? 24.18481  -0.37741  -34.42566 1.000 51.74222  ? 420 ILE A CB  1 
ATOM   3185 C  CG1 . ILE A 1 420 ? 23.93930  -1.87809  -34.26799 1.000 59.96075  ? 420 ILE A CG1 1 
ATOM   3186 C  CG2 . ILE A 1 420 ? 22.86691  0.38213   -34.49594 1.000 51.52971  ? 420 ILE A CG2 1 
ATOM   3187 C  CD1 . ILE A 1 420 ? 22.85297  -2.22394  -33.27905 1.000 48.98077  ? 420 ILE A CD1 1 
ATOM   3188 N  N   . LEU A 1 421 ? 26.16279  1.99913   -35.18915 1.000 64.35103  ? 421 LEU A N   1 
ATOM   3189 C  CA  . LEU A 1 421 ? 26.41845  3.42898   -35.31670 1.000 48.80076  ? 421 LEU A CA  1 
ATOM   3190 C  C   . LEU A 1 421 ? 27.28575  3.77440   -36.52338 1.000 53.33254  ? 421 LEU A C   1 
ATOM   3191 O  O   . LEU A 1 421 ? 27.68826  4.93391   -36.66708 1.000 77.33071  ? 421 LEU A O   1 
ATOM   3192 C  CB  . LEU A 1 421 ? 27.05185  3.96464   -34.02920 1.000 65.40190  ? 421 LEU A CB  1 
ATOM   3193 C  CG  . LEU A 1 421 ? 26.12116  3.90180   -32.81359 1.000 56.67670  ? 421 LEU A CG  1 
ATOM   3194 C  CD1 . LEU A 1 421 ? 26.77599  4.51753   -31.58869 1.000 59.66155  ? 421 LEU A CD1 1 
ATOM   3195 C  CD2 . LEU A 1 421 ? 24.78816  4.57739   -33.11155 1.000 59.16474  ? 421 LEU A CD2 1 
ATOM   3196 N  N   . GLY A 1 422 ? 27.58773  2.79980   -37.37573 1.000 61.42829  ? 422 GLY A N   1 
ATOM   3197 C  CA  . GLY A 1 422 ? 28.09896  3.08397   -38.70523 1.000 67.61795  ? 422 GLY A CA  1 
ATOM   3198 C  C   . GLY A 1 422 ? 29.57655  3.38493   -38.83395 1.000 74.13611  ? 422 GLY A C   1 
ATOM   3199 O  O   . GLY A 1 422 ? 29.95310  4.30116   -39.57342 1.000 83.67406  ? 422 GLY A O   1 
ATOM   3200 N  N   . LEU A 1 423 ? 30.43299  2.63514   -38.14301 1.000 66.45601  ? 423 LEU A N   1 
ATOM   3201 C  CA  . LEU A 1 423 ? 31.86566  2.70865   -38.39837 1.000 57.58437  ? 423 LEU A CA  1 
ATOM   3202 C  C   . LEU A 1 423 ? 32.37348  1.55137   -39.24543 1.000 60.67182  ? 423 LEU A C   1 
ATOM   3203 O  O   . LEU A 1 423 ? 33.45537  1.66165   -39.83425 1.000 65.87196  ? 423 LEU A O   1 
ATOM   3204 C  CB  . LEU A 1 423 ? 32.64943  2.75237   -37.08332 1.000 53.53957  ? 423 LEU A CB  1 
ATOM   3205 C  CG  . LEU A 1 423 ? 32.48705  4.00320   -36.21870 1.000 56.94356  ? 423 LEU A CG  1 
ATOM   3206 C  CD1 . LEU A 1 423 ? 33.36325  3.91148   -34.98323 1.000 57.05273  ? 423 LEU A CD1 1 
ATOM   3207 C  CD2 . LEU A 1 423 ? 32.82657  5.24641   -37.01919 1.000 75.34832  ? 423 LEU A CD2 1 
ATOM   3208 N  N   . VAL A 1 424 ? 31.61966  0.45387   -39.31493 1.000 65.04494  ? 424 VAL A N   1 
ATOM   3209 C  CA  . VAL A 1 424 ? 31.98797  -0.70515  -40.11872 1.000 65.40120  ? 424 VAL A CA  1 
ATOM   3210 C  C   . VAL A 1 424 ? 30.73479  -1.54625  -40.31011 1.000 72.95793  ? 424 VAL A C   1 
ATOM   3211 O  O   . VAL A 1 424 ? 29.81529  -1.50811  -39.48826 1.000 70.56288  ? 424 VAL A O   1 
ATOM   3212 C  CB  . VAL A 1 424 ? 33.13622  -1.50758  -39.45262 1.000 62.66655  ? 424 VAL A CB  1 
ATOM   3213 C  CG1 . VAL A 1 424 ? 32.62772  -2.28772  -38.24338 1.000 58.11706  ? 424 VAL A CG1 1 
ATOM   3214 C  CG2 . VAL A 1 424 ? 33.81096  -2.42277  -40.46065 1.000 60.64072  ? 424 VAL A CG2 1 
ATOM   3215 N  N   . ARG A 1 425 ? 30.68846  -2.29298  -41.41436 1.000 68.25632  ? 425 ARG A N   1 
ATOM   3216 C  CA  . ARG A 1 425 ? 29.58372  -3.20557  -41.68857 1.000 71.36671  ? 425 ARG A CA  1 
ATOM   3217 C  C   . ARG A 1 425 ? 29.94736  -4.65345  -41.38463 1.000 80.93969  ? 425 ARG A C   1 
ATOM   3218 O  O   . ARG A 1 425 ? 29.23353  -5.32986  -40.63953 1.000 81.01683  ? 425 ARG A O   1 
ATOM   3219 C  CB  . ARG A 1 425 ? 29.13393  -3.07358  -43.15062 1.000 73.94091  ? 425 ARG A CB  1 
ATOM   3220 C  CG  . ARG A 1 425 ? 27.79069  -3.72839  -43.44481 1.000 85.42693  ? 425 ARG A CG  1 
ATOM   3221 C  CD  . ARG A 1 425 ? 27.35440  -3.45373  -44.87211 1.000 77.37462  ? 425 ARG A CD  1 
ATOM   3222 N  NE  . ARG A 1 425 ? 25.90717  -3.54047  -45.04532 1.000 89.65689  ? 425 ARG A NE  1 
ATOM   3223 C  CZ  . ARG A 1 425 ? 25.29154  -4.44830  -45.79039 1.000 99.98197  ? 425 ARG A CZ  1 
ATOM   3224 N  NH1 . ARG A 1 425 ? 25.96749  -5.37158  -46.45539 1.000 88.76629  ? 425 ARG A NH1 1 
ATOM   3225 N  NH2 . ARG A 1 425 ? 23.96536  -4.42421  -45.87641 1.000 107.75439 ? 425 ARG A NH2 1 
ATOM   3226 N  N   . ASP A 1 426 ? 31.05130  -5.14142  -41.94590 1.000 74.15856  ? 426 ASP A N   1 
ATOM   3227 C  CA  . ASP A 1 426 ? 31.59459  -6.45033  -41.59896 1.000 66.80615  ? 426 ASP A CA  1 
ATOM   3228 C  C   . ASP A 1 426 ? 32.54527  -6.27499  -40.41958 1.000 69.28945  ? 426 ASP A C   1 
ATOM   3229 O  O   . ASP A 1 426 ? 33.57226  -5.59868  -40.54037 1.000 66.91010  ? 426 ASP A O   1 
ATOM   3230 C  CB  . ASP A 1 426 ? 32.31538  -7.07357  -42.79381 1.000 69.74773  ? 426 ASP A CB  1 
ATOM   3231 C  CG  . ASP A 1 426 ? 32.72495  -8.51647  -42.55187 1.000 66.74947  ? 426 ASP A CG  1 
ATOM   3232 O  OD1 . ASP A 1 426 ? 32.61154  -9.00319  -41.40471 1.000 68.67423  ? 426 ASP A OD1 1 
ATOM   3233 O  OD2 . ASP A 1 426 ? 33.16732  -9.16847  -43.52050 1.000 57.90809  ? 426 ASP A OD2 1 
ATOM   3234 N  N   . VAL A 1 427 ? 32.20373  -6.89106  -39.28534 1.000 62.93460  ? 427 VAL A N   1 
ATOM   3235 C  CA  . VAL A 1 427 ? 32.98198  -6.71303  -38.06088 1.000 51.50174  ? 427 VAL A CA  1 
ATOM   3236 C  C   . VAL A 1 427 ? 34.42351  -7.16816  -38.25142 1.000 59.42115  ? 427 VAL A C   1 
ATOM   3237 O  O   . VAL A 1 427 ? 35.32994  -6.69032  -37.55958 1.000 65.36102  ? 427 VAL A O   1 
ATOM   3238 C  CB  . VAL A 1 427 ? 32.30262  -7.45524  -36.88992 1.000 45.59392  ? 427 VAL A CB  1 
ATOM   3239 C  CG1 . VAL A 1 427 ? 32.94939  -7.07750  -35.56516 1.000 46.76599  ? 427 VAL A CG1 1 
ATOM   3240 C  CG2 . VAL A 1 427 ? 30.81608  -7.14762  -36.86208 1.000 41.76518  ? 427 VAL A CG2 1 
ATOM   3241 N  N   . ARG A 1 428 ? 34.66558  -8.08201  -39.19309 1.000 54.85979  ? 428 ARG A N   1 
ATOM   3242 C  CA  . ARG A 1 428 ? 36.01551  -8.56666  -39.45528 1.000 56.80407  ? 428 ARG A CA  1 
ATOM   3243 C  C   . ARG A 1 428 ? 36.94049  -7.48918  -40.00717 1.000 58.34093  ? 428 ARG A C   1 
ATOM   3244 O  O   . ARG A 1 428 ? 38.15786  -7.70126  -40.03538 1.000 51.68562  ? 428 ARG A O   1 
ATOM   3245 C  CB  . ARG A 1 428 ? 35.96266  -9.75012  -40.41875 1.000 66.84100  ? 428 ARG A CB  1 
ATOM   3246 C  CG  . ARG A 1 428 ? 35.31495  -10.98610 -39.82246 1.000 72.60800  ? 428 ARG A CG  1 
ATOM   3247 C  CD  . ARG A 1 428 ? 35.25838  -12.11257 -40.83263 1.000 55.35858  ? 428 ARG A CD  1 
ATOM   3248 N  NE  . ARG A 1 428 ? 34.18752  -11.90987 -41.80346 1.000 63.21488  ? 428 ARG A NE  1 
ATOM   3249 C  CZ  . ARG A 1 428 ? 34.20245  -12.38688 -43.03984 1.000 60.31361  ? 428 ARG A CZ  1 
ATOM   3250 N  NH1 . ARG A 1 428 ? 35.22150  -13.09935 -43.49281 1.000 65.82920  ? 428 ARG A NH1 1 
ATOM   3251 N  NH2 . ARG A 1 428 ? 33.17667  -12.13225 -43.84463 1.000 60.26192  ? 428 ARG A NH2 1 
ATOM   3252 N  N   . ASN A 1 429 ? 36.40059  -6.35407  -40.45348 1.000 67.55004  ? 429 ASN A N   1 
ATOM   3253 C  CA  . ASN A 1 429 ? 37.19904  -5.21742  -40.89064 1.000 69.73549  ? 429 ASN A CA  1 
ATOM   3254 C  C   . ASN A 1 429 ? 37.40248  -4.19978  -39.77666 1.000 74.07640  ? 429 ASN A C   1 
ATOM   3255 O  O   . ASN A 1 429 ? 37.74746  -3.04614  -40.05292 1.000 75.18564  ? 429 ASN A O   1 
ATOM   3256 C  CB  . ASN A 1 429 ? 36.55664  -4.54672  -42.10700 1.000 56.35760  ? 429 ASN A CB  1 
ATOM   3257 C  CG  . ASN A 1 429 ? 36.74267  -5.34679  -43.38307 1.000 59.12787  ? 429 ASN A CG  1 
ATOM   3258 O  OD1 . ASN A 1 429 ? 37.85290  -5.76564  -43.71235 1.000 69.22724  ? 429 ASN A OD1 1 
ATOM   3259 N  ND2 . ASN A 1 429 ? 35.65032  -5.56991  -44.10459 1.000 73.62549  ? 429 ASN A ND2 1 
ATOM   3260 N  N   . HIS A 1 430 ? 37.18210  -4.60357  -38.52724 1.000 75.33612  ? 430 HIS A N   1 
ATOM   3261 C  CA  . HIS A 1 430 ? 37.36573  -3.70399  -37.39734 1.000 61.76001  ? 430 HIS A CA  1 
ATOM   3262 C  C   . HIS A 1 430 ? 38.80819  -3.21566  -37.34186 1.000 67.64536  ? 430 HIS A C   1 
ATOM   3263 O  O   . HIS A 1 430 ? 39.74793  -3.96159  -37.62844 1.000 77.02114  ? 430 HIS A O   1 
ATOM   3264 C  CB  . HIS A 1 430 ? 36.99485  -4.41489  -36.09554 1.000 59.05997  ? 430 HIS A CB  1 
ATOM   3265 C  CG  . HIS A 1 430 ? 36.51801  -3.49797  -35.01353 1.000 66.44784  ? 430 HIS A CG  1 
ATOM   3266 N  ND1 . HIS A 1 430 ? 37.37878  -2.81738  -34.18061 1.000 64.81933  ? 430 HIS A ND1 1 
ATOM   3267 C  CD2 . HIS A 1 430 ? 35.26784  -3.15862  -34.62029 1.000 58.92178  ? 430 HIS A CD2 1 
ATOM   3268 C  CE1 . HIS A 1 430 ? 36.67979  -2.09213  -33.32583 1.000 71.03716  ? 430 HIS A CE1 1 
ATOM   3269 N  NE2 . HIS A 1 430 ? 35.39615  -2.28213  -33.57077 1.000 72.54683  ? 430 HIS A NE2 1 
ATOM   3270 N  N   . ALA A 1 431 ? 38.98221  -1.94837  -36.97115 1.000 61.21514  ? 431 ALA A N   1 
ATOM   3271 C  CA  . ALA A 1 431 ? 40.29318  -1.31598  -37.03993 1.000 66.64360  ? 431 ALA A CA  1 
ATOM   3272 C  C   . ALA A 1 431 ? 41.23380  -1.74654  -35.92304 1.000 71.00286  ? 431 ALA A C   1 
ATOM   3273 O  O   . ALA A 1 431 ? 42.43412  -1.46335  -36.00657 1.000 68.04712  ? 431 ALA A O   1 
ATOM   3274 C  CB  . ALA A 1 431 ? 40.14296  0.20461   -37.02204 1.000 59.38414  ? 431 ALA A CB  1 
ATOM   3275 N  N   . LEU A 1 432 ? 40.73183  -2.41408  -34.88543 1.000 66.58831  ? 432 LEU A N   1 
ATOM   3276 C  CA  . LEU A 1 432 ? 41.57051  -2.83691  -33.77176 1.000 60.67782  ? 432 LEU A CA  1 
ATOM   3277 C  C   . LEU A 1 432 ? 41.95670  -4.30520  -33.83334 1.000 70.31268  ? 432 LEU A C   1 
ATOM   3278 O  O   . LEU A 1 432 ? 42.72202  -4.75976  -32.97895 1.000 74.57258  ? 432 LEU A O   1 
ATOM   3279 C  CB  . LEU A 1 432 ? 40.86544  -2.53852  -32.44342 1.000 60.64353  ? 432 LEU A CB  1 
ATOM   3280 C  CG  . LEU A 1 432 ? 40.48540  -1.06513  -32.27718 1.000 76.79734  ? 432 LEU A CG  1 
ATOM   3281 C  CD1 . LEU A 1 432 ? 39.86927  -0.79796  -30.91710 1.000 69.81711  ? 432 LEU A CD1 1 
ATOM   3282 C  CD2 . LEU A 1 432 ? 41.69034  -0.15861  -32.51218 1.000 73.27450  ? 432 LEU A CD2 1 
ATOM   3283 N  N   . VAL A 1 433 ? 41.44621  -5.04918  -34.81674 1.000 68.92680  ? 433 VAL A N   1 
ATOM   3284 C  CA  . VAL A 1 433 ? 41.85458  -6.44754  -34.99630 1.000 55.59099  ? 433 VAL A CA  1 
ATOM   3285 C  C   . VAL A 1 433 ? 43.37364  -6.58392  -35.13023 1.000 57.64102  ? 433 VAL A C   1 
ATOM   3286 O  O   . VAL A 1 433 ? 43.94761  -7.47556  -34.49148 1.000 60.54398  ? 433 VAL A O   1 
ATOM   3287 C  CB  . VAL A 1 433 ? 41.09205  -7.08308  -36.15733 1.000 51.86726  ? 433 VAL A CB  1 
ATOM   3288 C  CG1 . VAL A 1 433 ? 41.50649  -8.53253  -36.34062 1.000 65.97132  ? 433 VAL A CG1 1 
ATOM   3289 C  CG2 . VAL A 1 433 ? 39.59304  -6.98178  -35.92507 1.000 52.47027  ? 433 VAL A CG2 1 
ATOM   3290 N  N   . PRO A 1 434 ? 44.07202  -5.76606  -35.93448 1.000 57.69821  ? 434 PRO A N   1 
ATOM   3291 C  CA  . PRO A 1 434 ? 45.54295  -5.87570  -35.96186 1.000 55.54208  ? 434 PRO A CA  1 
ATOM   3292 C  C   . PRO A 1 434 ? 46.19489  -5.65257  -34.60831 1.000 66.90701  ? 434 PRO A C   1 
ATOM   3293 O  O   . PRO A 1 434 ? 47.19124  -6.31314  -34.28844 1.000 78.85741  ? 434 PRO A O   1 
ATOM   3294 C  CB  . PRO A 1 434 ? 45.94832  -4.79475  -36.97136 1.000 63.79449  ? 434 PRO A CB  1 
ATOM   3295 C  CG  . PRO A 1 434 ? 44.76710  -4.63891  -37.84747 1.000 63.71005  ? 434 PRO A CG  1 
ATOM   3296 C  CD  . PRO A 1 434 ? 43.59025  -4.79748  -36.93676 1.000 62.08666  ? 434 PRO A CD  1 
ATOM   3297 N  N   . LEU A 1 435 ? 45.66239  -4.72914  -33.80449 1.000 69.55399  ? 435 LEU A N   1 
ATOM   3298 C  CA  . LEU A 1 435 ? 46.24725  -4.46087  -32.49400 1.000 62.35851  ? 435 LEU A CA  1 
ATOM   3299 C  C   . LEU A 1 435 ? 46.06497  -5.64075  -31.54819 1.000 64.56466  ? 435 LEU A C   1 
ATOM   3300 O  O   . LEU A 1 435 ? 46.95619  -5.94060  -30.74444 1.000 72.59620  ? 435 LEU A O   1 
ATOM   3301 C  CB  . LEU A 1 435 ? 45.63602  -3.19512  -31.89561 1.000 59.67325  ? 435 LEU A CB  1 
ATOM   3302 C  CG  . LEU A 1 435 ? 46.06205  -1.88170  -32.55063 1.000 63.59812  ? 435 LEU A CG  1 
ATOM   3303 C  CD1 . LEU A 1 435 ? 45.33473  -0.70294  -31.92206 1.000 57.85635  ? 435 LEU A CD1 1 
ATOM   3304 C  CD2 . LEU A 1 435 ? 47.56998  -1.70956  -32.44647 1.000 66.40814  ? 435 LEU A CD2 1 
ATOM   3305 N  N   . ILE A 1 436 ? 44.91515  -6.31569  -31.62543 1.000 58.76754  ? 436 ILE A N   1 
ATOM   3306 C  CA  . ILE A 1 436 ? 44.67078  -7.47692  -30.77398 1.000 63.20207  ? 436 ILE A CA  1 
ATOM   3307 C  C   . ILE A 1 436 ? 45.72701  -8.54716  -31.01848 1.000 68.16086  ? 436 ILE A C   1 
ATOM   3308 O  O   . ILE A 1 436 ? 46.19296  -9.20659  -30.08159 1.000 77.89153  ? 436 ILE A O   1 
ATOM   3309 C  CB  . ILE A 1 436 ? 43.24741  -8.02037  -31.00245 1.000 63.10581  ? 436 ILE A CB  1 
ATOM   3310 C  CG1 . ILE A 1 436 ? 42.20609  -6.92729  -30.74667 1.000 46.90238  ? 436 ILE A CG1 1 
ATOM   3311 C  CG2 . ILE A 1 436 ? 42.98602  -9.22753  -30.11418 1.000 51.40014  ? 436 ILE A CG2 1 
ATOM   3312 C  CD1 . ILE A 1 436 ? 40.77688  -7.41964  -30.80496 1.000 47.66206  ? 436 ILE A CD1 1 
ATOM   3313 N  N   . ALA A 1 437 ? 46.13755  -8.72102  -32.27439 1.000 68.33372  ? 437 ALA A N   1 
ATOM   3314 C  CA  . ALA A 1 437 ? 47.12725  -9.72877  -32.63113 1.000 73.60809  ? 437 ALA A CA  1 
ATOM   3315 C  C   . ALA A 1 437 ? 48.54339  -9.35986  -32.20849 1.000 77.39324  ? 437 ALA A C   1 
ATOM   3316 O  O   . ALA A 1 437 ? 49.46808  -10.13030 -32.48821 1.000 82.01578  ? 437 ALA A O   1 
ATOM   3317 C  CB  . ALA A 1 437 ? 47.09347  -9.98799  -34.13937 1.000 60.96981  ? 437 ALA A CB  1 
ATOM   3318 N  N   . ASP A 1 438 ? 48.74884  -8.21383  -31.55791 1.000 67.57708  ? 438 ASP A N   1 
ATOM   3319 C  CA  . ASP A 1 438 ? 50.06593  -7.84304  -31.05061 1.000 70.75922  ? 438 ASP A CA  1 
ATOM   3320 C  C   . ASP A 1 438 ? 49.99645  -7.50254  -29.56849 1.000 75.99413  ? 438 ASP A C   1 
ATOM   3321 O  O   . ASP A 1 438 ? 50.72924  -6.63973  -29.07564 1.000 77.46501  ? 438 ASP A O   1 
ATOM   3322 C  CB  . ASP A 1 438 ? 50.66137  -6.68595  -31.84764 1.000 66.67605  ? 438 ASP A CB  1 
ATOM   3323 C  CG  . ASP A 1 438 ? 52.17903  -6.69840  -31.83569 1.000 76.22706  ? 438 ASP A CG  1 
ATOM   3324 O  OD1 . ASP A 1 438 ? 52.76127  -7.70250  -31.36577 1.000 69.97048  ? 438 ASP A OD1 1 
ATOM   3325 O  OD2 . ASP A 1 438 ? 52.78595  -5.70769  -32.29592 1.000 90.04930  ? 438 ASP A OD2 1 
ATOM   3326 N  N   . ASP A 1 439 ? 49.12429  -8.19870  -28.84243 1.000 78.44582  ? 439 ASP A N   1 
ATOM   3327 C  CA  . ASP A 1 439 ? 48.95137  -8.06258  -27.39177 1.000 76.51206  ? 439 ASP A CA  1 
ATOM   3328 C  C   . ASP A 1 439 ? 48.94246  -6.59859  -26.95214 1.000 77.51639  ? 439 ASP A C   1 
ATOM   3329 O  O   . ASP A 1 439 ? 49.73726  -6.15687  -26.12325 1.000 78.09316  ? 439 ASP A O   1 
ATOM   3330 C  CB  . ASP A 1 439 ? 50.02130  -8.85002  -26.64137 1.000 82.16811  ? 439 ASP A CB  1 
ATOM   3331 C  CG  . ASP A 1 439 ? 49.53105  -9.36603  -25.30174 1.000 84.48037  ? 439 ASP A CG  1 
ATOM   3332 O  OD1 . ASP A 1 439 ? 48.67400  -8.70160  -24.68049 1.000 85.48463  ? 439 ASP A OD1 1 
ATOM   3333 O  OD2 . ASP A 1 439 ? 49.99579  -10.44170 -24.87306 1.000 94.81769  ? 439 ASP A OD2 1 
ATOM   3334 N  N   . TYR A 1 440 ? 48.01885  -5.84628  -27.53723 1.000 77.36548  ? 440 TYR A N   1 
ATOM   3335 C  CA  . TYR A 1 440 ? 47.80036  -4.44982  -27.18568 1.000 67.40199  ? 440 TYR A CA  1 
ATOM   3336 C  C   . TYR A 1 440 ? 46.84192  -4.36554  -26.00122 1.000 68.33551  ? 440 TYR A C   1 
ATOM   3337 O  O   . TYR A 1 440 ? 45.91742  -5.17854  -25.89846 1.000 77.56440  ? 440 TYR A O   1 
ATOM   3338 C  CB  . TYR A 1 440 ? 47.22613  -3.68697  -28.37153 1.000 73.71916  ? 440 TYR A CB  1 
ATOM   3339 C  CG  . TYR A 1 440 ? 47.46038  -2.19818  -28.32255 1.000 76.09676  ? 440 TYR A CG  1 
ATOM   3340 C  CD1 . TYR A 1 440 ? 48.67130  -1.65644  -28.73177 1.000 70.32250  ? 440 TYR A CD1 1 
ATOM   3341 C  CD2 . TYR A 1 440 ? 46.47313  -1.33582  -27.87092 1.000 73.39003  ? 440 TYR A CD2 1 
ATOM   3342 C  CE1 . TYR A 1 440 ? 48.89191  -0.29472  -28.68872 1.000 78.18428  ? 440 TYR A CE1 1 
ATOM   3343 C  CE2 . TYR A 1 440 ? 46.68437  0.02795   -27.82502 1.000 78.37533  ? 440 TYR A CE2 1 
ATOM   3344 C  CZ  . TYR A 1 440 ? 47.89496  0.54279   -28.23572 1.000 86.73463  ? 440 TYR A CZ  1 
ATOM   3345 O  OH  . TYR A 1 440 ? 48.10447  1.89986   -28.19093 1.000 92.01479  ? 440 TYR A OH  1 
ATOM   3346 N  N   . PRO A 1 441 ? 47.04371  -3.41934  -25.07169 1.000 76.00594  ? 441 PRO A N   1 
ATOM   3347 C  CA  . PRO A 1 441 ? 46.09898  -3.28292  -23.95327 1.000 73.78089  ? 441 PRO A CA  1 
ATOM   3348 C  C   . PRO A 1 441 ? 44.69565  -2.97473  -24.44348 1.000 72.89222  ? 441 PRO A C   1 
ATOM   3349 O  O   . PRO A 1 441 ? 44.43427  -1.88495  -24.95854 1.000 70.06851  ? 441 PRO A O   1 
ATOM   3350 C  CB  . PRO A 1 441 ? 46.68459  -2.12579  -23.13089 1.000 73.56021  ? 441 PRO A CB  1 
ATOM   3351 C  CG  . PRO A 1 441 ? 47.61208  -1.40798  -24.06689 1.000 79.92991  ? 441 PRO A CG  1 
ATOM   3352 C  CD  . PRO A 1 441 ? 48.15853  -2.46274  -24.97693 1.000 66.28350  ? 441 PRO A CD  1 
ATOM   3353 N  N   . ILE A 1 442 ? 43.78117  -3.92934  -24.28319 1.000 70.87134  ? 442 ILE A N   1 
ATOM   3354 C  CA  . ILE A 1 442 ? 42.42228  -3.80582  -24.79750 1.000 72.69755  ? 442 ILE A CA  1 
ATOM   3355 C  C   . ILE A 1 442 ? 41.47434  -4.51535  -23.84112 1.000 60.58946  ? 442 ILE A C   1 
ATOM   3356 O  O   . ILE A 1 442 ? 41.84321  -5.48897  -23.17834 1.000 57.55472  ? 442 ILE A O   1 
ATOM   3357 C  CB  . ILE A 1 442 ? 42.27687  -4.39718  -26.22355 1.000 67.59535  ? 442 ILE A CB  1 
ATOM   3358 C  CG1 . ILE A 1 442 ? 42.73368  -5.85738  -26.23581 1.000 68.56239  ? 442 ILE A CG1 1 
ATOM   3359 C  CG2 . ILE A 1 442 ? 43.00916  -3.54159  -27.27082 1.000 57.67372  ? 442 ILE A CG2 1 
ATOM   3360 C  CD1 . ILE A 1 442 ? 41.99401  -6.71815  -27.23027 1.000 87.64639  ? 442 ILE A CD1 1 
ATOM   3361 N  N   . VAL A 1 443 ? 40.24101  -4.00921  -23.76772 1.000 65.58885  ? 443 VAL A N   1 
ATOM   3362 C  CA  . VAL A 1 443 ? 39.14797  -4.65822  -23.05666 1.000 58.32159  ? 443 VAL A CA  1 
ATOM   3363 C  C   . VAL A 1 443 ? 37.92748  -4.64820  -23.96804 1.000 64.04682  ? 443 VAL A C   1 
ATOM   3364 O  O   . VAL A 1 443 ? 37.88010  -3.93347  -24.97033 1.000 68.90046  ? 443 VAL A O   1 
ATOM   3365 C  CB  . VAL A 1 443 ? 38.81974  -3.98466  -21.70290 1.000 50.69979  ? 443 VAL A CB  1 
ATOM   3366 C  CG1 . VAL A 1 443 ? 40.07364  -3.82279  -20.85605 1.000 46.84295  ? 443 VAL A CG1 1 
ATOM   3367 C  CG2 . VAL A 1 443 ? 38.14456  -2.64525  -21.92374 1.000 65.93025  ? 443 VAL A CG2 1 
ATOM   3368 N  N   . ILE A 1 444 ? 36.93417  -5.46056  -23.61413 1.000 51.54037  ? 444 ILE A N   1 
ATOM   3369 C  CA  . ILE A 1 444 ? 35.70227  -5.58029  -24.38562 1.000 54.18182  ? 444 ILE A CA  1 
ATOM   3370 C  C   . ILE A 1 444 ? 34.53163  -5.12942  -23.52302 1.000 58.62710  ? 444 ILE A C   1 
ATOM   3371 O  O   . ILE A 1 444 ? 34.47162  -5.43709  -22.32737 1.000 66.39008  ? 444 ILE A O   1 
ATOM   3372 C  CB  . ILE A 1 444 ? 35.49561  -7.02137  -24.90043 1.000 64.18903  ? 444 ILE A CB  1 
ATOM   3373 C  CG1 . ILE A 1 444 ? 36.44637  -7.30631  -26.06428 1.000 70.47947  ? 444 ILE A CG1 1 
ATOM   3374 C  CG2 . ILE A 1 444 ? 34.04671  -7.26237  -25.32554 1.000 62.51797  ? 444 ILE A CG2 1 
ATOM   3375 C  CD1 . ILE A 1 444 ? 36.09168  -6.57283  -27.34187 1.000 64.25513  ? 444 ILE A CD1 1 
ATOM   3376 N  N   . SER A 1 445 ? 33.60712  -4.39117  -24.13210 1.000 58.75976  ? 445 SER A N   1 
ATOM   3377 C  CA  . SER A 1 445 ? 32.43418  -3.89158  -23.42888 1.000 66.91151  ? 445 SER A CA  1 
ATOM   3378 C  C   . SER A 1 445 ? 31.33733  -3.61953  -24.44820 1.000 70.10172  ? 445 SER A C   1 
ATOM   3379 O  O   . SER A 1 445 ? 31.57693  -3.59773  -25.65535 1.000 81.98703  ? 445 SER A O   1 
ATOM   3380 C  CB  . SER A 1 445 ? 32.76465  -2.62701  -22.63089 1.000 75.26041  ? 445 SER A CB  1 
ATOM   3381 O  OG  . SER A 1 445 ? 31.61787  -2.09177  -21.99307 1.000 77.41106  ? 445 SER A OG  1 
ATOM   3382 N  N   . SER A 1 446 ? 30.12227  -3.42496  -23.94560 1.000 63.67482  ? 446 SER A N   1 
ATOM   3383 C  CA  . SER A 1 446 ? 29.03914  -2.88428  -24.74922 1.000 62.42047  ? 446 SER A CA  1 
ATOM   3384 C  C   . SER A 1 446 ? 29.08213  -1.36258  -24.63691 1.000 83.40536  ? 446 SER A C   1 
ATOM   3385 O  O   . SER A 1 446 ? 29.99723  -0.80092  -24.03549 1.000 94.80379  ? 446 SER A O   1 
ATOM   3386 C  CB  . SER A 1 446 ? 27.69947  -3.45739  -24.30070 1.000 63.57092  ? 446 SER A CB  1 
ATOM   3387 O  OG  . SER A 1 446 ? 27.54360  -3.32420  -22.89980 1.000 66.58007  ? 446 SER A OG  1 
ATOM   3388 N  N   . ASP A 1 447 ? 28.14103  -0.66742  -25.27983 1.000 77.55193  ? 447 ASP A N   1 
ATOM   3389 C  CA  . ASP A 1 447 ? 27.99169  0.76497   -25.03462 1.000 68.11655  ? 447 ASP A CA  1 
ATOM   3390 C  C   . ASP A 1 447 ? 26.60698  1.12101   -24.51082 1.000 67.62453  ? 447 ASP A C   1 
ATOM   3391 O  O   . ASP A 1 447 ? 26.48978  1.66348   -23.40723 1.000 65.31560  ? 447 ASP A O   1 
ATOM   3392 C  CB  . ASP A 1 447 ? 28.31203  1.55922   -26.30819 1.000 70.71962  ? 447 ASP A CB  1 
ATOM   3393 C  CG  . ASP A 1 447 ? 28.69287  3.00294   -26.01582 1.000 87.39450  ? 447 ASP A CG  1 
ATOM   3394 O  OD1 . ASP A 1 447 ? 28.71521  3.37998   -24.82524 1.000 81.15290  ? 447 ASP A OD1 1 
ATOM   3395 O  OD2 . ASP A 1 447 ? 28.97470  3.75814   -26.97298 1.000 90.65670  ? 447 ASP A OD2 1 
ATOM   3396 N  N   . ASP A 1 448 ? 25.55246  0.81412   -25.26163 1.000 69.75057  ? 448 ASP A N   1 
ATOM   3397 C  CA  . ASP A 1 448 ? 24.17251  1.09793   -24.86884 1.000 65.02715  ? 448 ASP A CA  1 
ATOM   3398 C  C   . ASP A 1 448 ? 23.34218  -0.13862  -25.18637 1.000 67.10716  ? 448 ASP A C   1 
ATOM   3399 O  O   . ASP A 1 448 ? 22.49550  -0.12277  -26.08990 1.000 60.88988  ? 448 ASP A O   1 
ATOM   3400 C  CB  . ASP A 1 448 ? 23.62996  2.33346   -25.59007 1.000 71.50450  ? 448 ASP A CB  1 
ATOM   3401 C  CG  . ASP A 1 448 ? 24.40329  3.59822   -25.24804 1.000 78.29304  ? 448 ASP A CG  1 
ATOM   3402 O  OD1 . ASP A 1 448 ? 25.50711  3.79395   -25.79952 1.000 73.64796  ? 448 ASP A OD1 1 
ATOM   3403 O  OD2 . ASP A 1 448 ? 23.90382  4.39919   -24.42864 1.000 76.06153  ? 448 ASP A OD2 1 
ATOM   3404 N  N   . PRO A 1 449 ? 23.56888  -1.23833  -24.46151 1.000 66.74464  ? 449 PRO A N   1 
ATOM   3405 C  CA  . PRO A 1 449 ? 22.99149  -2.52577  -24.88364 1.000 49.62664  ? 449 PRO A CA  1 
ATOM   3406 C  C   . PRO A 1 449 ? 21.47372  -2.54953  -24.92848 1.000 50.36796  ? 449 PRO A C   1 
ATOM   3407 O  O   . PRO A 1 449 ? 20.90233  -3.31571  -25.71450 1.000 59.27799  ? 449 PRO A O   1 
ATOM   3408 C  CB  . PRO A 1 449 ? 23.55251  -3.50640  -23.84641 1.000 56.51256  ? 449 PRO A CB  1 
ATOM   3409 C  CG  . PRO A 1 449 ? 23.84034  -2.66461  -22.64671 1.000 53.97793  ? 449 PRO A CG  1 
ATOM   3410 C  CD  . PRO A 1 449 ? 24.31650  -1.35375  -23.19842 1.000 68.49233  ? 449 PRO A CD  1 
ATOM   3411 N  N   . GLY A 1 450 ? 20.79572  -1.73513  -24.11807 1.000 46.47801  ? 450 GLY A N   1 
ATOM   3412 C  CA  . GLY A 1 450 ? 19.33922  -1.77200  -24.08231 1.000 54.33304  ? 450 GLY A CA  1 
ATOM   3413 C  C   . GLY A 1 450 ? 18.66167  -1.14516  -25.28160 1.000 64.25320  ? 450 GLY A C   1 
ATOM   3414 O  O   . GLY A 1 450 ? 17.49818  -1.45970  -25.55353 1.000 69.18494  ? 450 GLY A O   1 
ATOM   3415 N  N   . ALA A 1 451 ? 19.35853  -0.26375  -26.00267 1.000 53.03182  ? 451 ALA A N   1 
ATOM   3416 C  CA  . ALA A 1 451 ? 18.74080  0.40269   -27.14607 1.000 60.45781  ? 451 ALA A CA  1 
ATOM   3417 C  C   . ALA A 1 451 ? 18.50241  -0.56820  -28.29758 1.000 65.74452  ? 451 ALA A C   1 
ATOM   3418 O  O   . ALA A 1 451 ? 17.43889  -0.54342  -28.92953 1.000 59.83887  ? 451 ALA A O   1 
ATOM   3419 C  CB  . ALA A 1 451 ? 19.60629  1.57471   -27.60521 1.000 61.27217  ? 451 ALA A CB  1 
ATOM   3420 N  N   . TRP A 1 452 ? 19.47589  -1.43284  -28.58423 1.000 69.40171  ? 452 TRP A N   1 
ATOM   3421 C  CA  . TRP A 1 452 ? 19.36275  -2.40418  -29.66261 1.000 60.86871  ? 452 TRP A CA  1 
ATOM   3422 C  C   . TRP A 1 452 ? 19.07907  -3.81411  -29.15535 1.000 58.37359  ? 452 TRP A C   1 
ATOM   3423 O  O   . TRP A 1 452 ? 19.36807  -4.78813  -29.86063 1.000 67.47661  ? 452 TRP A O   1 
ATOM   3424 C  CB  . TRP A 1 452 ? 20.62386  -2.39059  -30.52739 1.000 67.87876  ? 452 TRP A CB  1 
ATOM   3425 C  CG  . TRP A 1 452 ? 21.90854  -2.22102  -29.76992 1.000 59.66473  ? 452 TRP A CG  1 
ATOM   3426 C  CD1 . TRP A 1 452 ? 22.60312  -3.18823  -29.10366 1.000 61.15803  ? 452 TRP A CD1 1 
ATOM   3427 C  CD2 . TRP A 1 452 ? 22.66430  -1.01163  -29.62358 1.000 55.02259  ? 452 TRP A CD2 1 
ATOM   3428 N  NE1 . TRP A 1 452 ? 23.73923  -2.65416  -28.54290 1.000 67.52529  ? 452 TRP A NE1 1 
ATOM   3429 C  CE2 . TRP A 1 452 ? 23.80015  -1.31992  -28.84795 1.000 66.93149  ? 452 TRP A CE2 1 
ATOM   3430 C  CE3 . TRP A 1 452 ? 22.48851  0.30186   -30.06892 1.000 57.19624  ? 452 TRP A CE3 1 
ATOM   3431 C  CZ2 . TRP A 1 452 ? 24.75481  -0.36303  -28.50781 1.000 65.04751  ? 452 TRP A CZ2 1 
ATOM   3432 C  CZ3 . TRP A 1 452 ? 23.43776  1.24984   -29.73014 1.000 69.51400  ? 452 TRP A CZ3 1 
ATOM   3433 C  CH2 . TRP A 1 452 ? 24.55586  0.91312   -28.95732 1.000 59.19091  ? 452 TRP A CH2 1 
ATOM   3434 N  N   . GLU A 1 453 ? 18.51831  -3.93780  -27.95179 1.000 49.18931  ? 453 GLU A N   1 
ATOM   3435 C  CA  . GLU A 1 453 ? 18.05986  -5.21681  -27.40605 1.000 51.47413  ? 453 GLU A CA  1 
ATOM   3436 C  C   . GLU A 1 453 ? 19.16270  -6.27393  -27.42879 1.000 47.99898  ? 453 GLU A C   1 
ATOM   3437 O  O   . GLU A 1 453 ? 18.98753  -7.38234  -27.93704 1.000 53.16606  ? 453 GLU A O   1 
ATOM   3438 C  CB  . GLU A 1 453 ? 16.81549  -5.71045  -28.14412 1.000 50.69950  ? 453 GLU A CB  1 
ATOM   3439 C  CG  . GLU A 1 453 ? 15.60245  -4.80671  -28.00435 1.000 52.39165  ? 453 GLU A CG  1 
ATOM   3440 C  CD  . GLU A 1 453 ? 14.36773  -5.38607  -28.66659 1.000 77.39791  ? 453 GLU A CD  1 
ATOM   3441 O  OE1 . GLU A 1 453 ? 14.18978  -6.62199  -28.61623 1.000 80.57322  ? 453 GLU A OE1 1 
ATOM   3442 O  OE2 . GLU A 1 453 ? 13.57827  -4.60801  -29.24235 1.000 78.86576  ? 453 GLU A OE2 1 
ATOM   3443 N  N   . ALA A 1 454 ? 20.31152  -5.92340  -26.86191 1.000 46.59303  ? 454 ALA A N   1 
ATOM   3444 C  CA  . ALA A 1 454 ? 21.42519  -6.84816  -26.73363 1.000 48.46766  ? 454 ALA A CA  1 
ATOM   3445 C  C   . ALA A 1 454 ? 21.63055  -7.21686  -25.26928 1.000 63.55443  ? 454 ALA A C   1 
ATOM   3446 O  O   . ALA A 1 454 ? 21.22108  -6.49139  -24.35889 1.000 63.27457  ? 454 ALA A O   1 
ATOM   3447 C  CB  . ALA A 1 454 ? 22.71051  -6.24190  -27.30679 1.000 49.30591  ? 454 ALA A CB  1 
ATOM   3448 N  N   . SER A 1 455 ? 22.27270  -8.36291  -25.05267 1.000 65.52171  ? 455 SER A N   1 
ATOM   3449 C  CA  . SER A 1 455 ? 22.58368  -8.81078  -23.70966 1.000 57.17840  ? 455 SER A CA  1 
ATOM   3450 C  C   . SER A 1 455 ? 23.64916  -7.90166  -23.10198 1.000 65.66402  ? 455 SER A C   1 
ATOM   3451 O  O   . SER A 1 455 ? 24.34764  -7.18856  -23.82549 1.000 54.83870  ? 455 SER A O   1 
ATOM   3452 C  CB  . SER A 1 455 ? 23.05340  -10.26287 -23.72772 1.000 56.70247  ? 455 SER A CB  1 
ATOM   3453 O  OG  . SER A 1 455 ? 24.23792  -10.40222 -24.48857 1.000 66.61105  ? 455 SER A OG  1 
ATOM   3454 N  N   . PRO A 1 456 ? 23.77794  -7.89139  -21.75669 1.000 64.72335  ? 456 PRO A N   1 
ATOM   3455 C  CA  . PRO A 1 456 ? 24.74044  -6.98646  -21.11283 1.000 61.60093  ? 456 PRO A CA  1 
ATOM   3456 C  C   . PRO A 1 456 ? 26.14380  -7.05329  -21.69868 1.000 66.82772  ? 456 PRO A C   1 
ATOM   3457 O  O   . PRO A 1 456 ? 26.66644  -6.04059  -22.17676 1.000 62.21087  ? 456 PRO A O   1 
ATOM   3458 C  CB  . PRO A 1 456 ? 24.72734  -7.45121  -19.65640 1.000 63.90548  ? 456 PRO A CB  1 
ATOM   3459 C  CG  . PRO A 1 456 ? 23.36358  -8.01350  -19.46487 1.000 69.13146  ? 456 PRO A CG  1 
ATOM   3460 C  CD  . PRO A 1 456 ? 22.99646  -8.65383  -20.77325 1.000 60.56462  ? 456 PRO A CD  1 
ATOM   3461 N  N   . LEU A 1 457 ? 26.76628  -8.23060  -21.67271 1.000 62.92460  ? 457 LEU A N   1 
ATOM   3462 C  CA  . LEU A 1 457 ? 28.09955  -8.37923  -22.24667 1.000 64.90438  ? 457 LEU A CA  1 
ATOM   3463 C  C   . LEU A 1 457 ? 28.28580  -9.65245  -23.05755 1.000 69.22492  ? 457 LEU A C   1 
ATOM   3464 O  O   . LEU A 1 457 ? 29.30540  -9.77112  -23.74324 1.000 66.09996  ? 457 LEU A O   1 
ATOM   3465 C  CB  . LEU A 1 457 ? 29.16387  -8.32124  -21.14162 1.000 49.92464  ? 457 LEU A CB  1 
ATOM   3466 C  CG  . LEU A 1 457 ? 30.56359  -7.88300  -21.57294 1.000 61.29066  ? 457 LEU A CG  1 
ATOM   3467 C  CD1 . LEU A 1 457 ? 30.45882  -6.68927  -22.49944 1.000 54.08457  ? 457 LEU A CD1 1 
ATOM   3468 C  CD2 . LEU A 1 457 ? 31.42124  -7.54747  -20.36527 1.000 69.04487  ? 457 LEU A CD2 1 
ATOM   3469 N  N   . SER A 1 458 ? 27.35035  -10.60412 -23.00608 1.000 66.21154  ? 458 SER A N   1 
ATOM   3470 C  CA  . SER A 1 458 ? 27.52980  -11.87281 -23.70594 1.000 61.14962  ? 458 SER A CA  1 
ATOM   3471 C  C   . SER A 1 458 ? 27.56782  -11.67732 -25.21688 1.000 62.03737  ? 458 SER A C   1 
ATOM   3472 O  O   . SER A 1 458 ? 28.43120  -12.23552 -25.90496 1.000 65.50817  ? 458 SER A O   1 
ATOM   3473 C  CB  . SER A 1 458 ? 26.41459  -12.84538 -23.32121 1.000 67.70725  ? 458 SER A CB  1 
ATOM   3474 O  OG  . SER A 1 458 ? 26.56943  -13.33187 -22.00017 1.000 59.88594  ? 458 SER A OG  1 
ATOM   3475 N  N   . HIS A 1 459 ? 26.63243  -10.88871 -25.75209 1.000 64.22652  ? 459 HIS A N   1 
ATOM   3476 C  CA  . HIS A 1 459 ? 26.55255  -10.70730 -27.19754 1.000 59.29564  ? 459 HIS A CA  1 
ATOM   3477 C  C   . HIS A 1 459 ? 27.80025  -10.03578 -27.75462 1.000 59.26666  ? 459 HIS A C   1 
ATOM   3478 O  O   . HIS A 1 459 ? 28.18261  -10.29395 -28.89830 1.000 66.66916  ? 459 HIS A O   1 
ATOM   3479 C  CB  . HIS A 1 459 ? 25.30647  -9.89603  -27.55867 1.000 52.32828  ? 459 HIS A CB  1 
ATOM   3480 C  CG  . HIS A 1 459 ? 24.07469  -10.72786 -27.73949 1.000 50.41887  ? 459 HIS A CG  1 
ATOM   3481 N  ND1 . HIS A 1 459 ? 22.82384  -10.29898 -27.35427 1.000 47.01101  ? 459 HIS A ND1 1 
ATOM   3482 C  CD2 . HIS A 1 459 ? 23.90065  -11.95917 -28.27441 1.000 59.15067  ? 459 HIS A CD2 1 
ATOM   3483 C  CE1 . HIS A 1 459 ? 21.93282  -11.23163 -27.63997 1.000 52.40877  ? 459 HIS A CE1 1 
ATOM   3484 N  NE2 . HIS A 1 459 ? 22.56042  -12.24963 -28.19917 1.000 52.14380  ? 459 HIS A NE2 1 
ATOM   3485 N  N   . ASP A 1 460 ? 28.44912  -9.17815  -26.96995 1.000 61.50478  ? 460 ASP A N   1 
ATOM   3486 C  CA  . ASP A 1 460 ? 29.65337  -8.51325  -27.45308 1.000 62.28451  ? 460 ASP A CA  1 
ATOM   3487 C  C   . ASP A 1 460 ? 30.89273  -9.37811  -27.26627 1.000 59.65645  ? 460 ASP A C   1 
ATOM   3488 O  O   . ASP A 1 460 ? 31.85838  -9.24050  -28.02743 1.000 52.51914  ? 460 ASP A O   1 
ATOM   3489 C  CB  . ASP A 1 460 ? 29.82706  -7.15936  -26.76044 1.000 78.13916  ? 460 ASP A CB  1 
ATOM   3490 C  CG  . ASP A 1 460 ? 28.67378  -6.20839  -27.04105 1.000 80.80239  ? 460 ASP A CG  1 
ATOM   3491 O  OD1 . ASP A 1 460 ? 27.57771  -6.41315  -26.47697 1.000 79.56397  ? 460 ASP A OD1 1 
ATOM   3492 O  OD2 . ASP A 1 460 ? 28.86814  -5.26282  -27.83388 1.000 62.78125  ? 460 ASP A OD2 1 
ATOM   3493 N  N   . PHE A 1 461 ? 30.89000  -10.25937 -26.26435 1.000 58.25695  ? 461 PHE A N   1 
ATOM   3494 C  CA  . PHE A 1 461 ? 31.96203  -11.24029 -26.14621 1.000 52.58633  ? 461 PHE A CA  1 
ATOM   3495 C  C   . PHE A 1 461 ? 31.89716  -12.25604 -27.28119 1.000 61.67037  ? 461 PHE A C   1 
ATOM   3496 O  O   . PHE A 1 461 ? 32.93439  -12.69670 -27.79250 1.000 57.92385  ? 461 PHE A O   1 
ATOM   3497 C  CB  . PHE A 1 461 ? 31.88269  -11.93861 -24.78980 1.000 61.53856  ? 461 PHE A CB  1 
ATOM   3498 C  CG  . PHE A 1 461 ? 32.91307  -11.47069 -23.80041 1.000 61.60098  ? 461 PHE A CG  1 
ATOM   3499 C  CD1 . PHE A 1 461 ? 32.86554  -10.18698 -23.28233 1.000 60.43922  ? 461 PHE A CD1 1 
ATOM   3500 C  CD2 . PHE A 1 461 ? 33.92730  -12.31823 -23.38350 1.000 62.11159  ? 461 PHE A CD2 1 
ATOM   3501 C  CE1 . PHE A 1 461 ? 33.81410  -9.75528  -22.37267 1.000 61.56555  ? 461 PHE A CE1 1 
ATOM   3502 C  CE2 . PHE A 1 461 ? 34.87839  -11.89264 -22.47328 1.000 60.04343  ? 461 PHE A CE2 1 
ATOM   3503 C  CZ  . PHE A 1 461 ? 34.82128  -10.60976 -21.96786 1.000 70.65407  ? 461 PHE A CZ  1 
ATOM   3504 N  N   . TYR A 1 462 ? 30.68260  -12.63562 -27.68568 1.000 63.28137  ? 462 TYR A N   1 
ATOM   3505 C  CA  . TYR A 1 462 ? 30.51269  -13.58012 -28.78553 1.000 64.68100  ? 462 TYR A CA  1 
ATOM   3506 C  C   . TYR A 1 462 ? 31.01615  -12.99391 -30.09883 1.000 66.72807  ? 462 TYR A C   1 
ATOM   3507 O  O   . TYR A 1 462 ? 31.71965  -13.66659 -30.86134 1.000 64.91323  ? 462 TYR A O   1 
ATOM   3508 C  CB  . TYR A 1 462 ? 29.03931  -13.98190 -28.90170 1.000 57.89596  ? 462 TYR A CB  1 
ATOM   3509 C  CG  . TYR A 1 462 ? 28.74943  -14.96298 -30.01935 1.000 63.69956  ? 462 TYR A CG  1 
ATOM   3510 C  CD1 . TYR A 1 462 ? 28.46953  -14.51840 -31.30679 1.000 57.72581  ? 462 TYR A CD1 1 
ATOM   3511 C  CD2 . TYR A 1 462 ? 28.74838  -16.33297 -29.78794 1.000 73.34773  ? 462 TYR A CD2 1 
ATOM   3512 C  CE1 . TYR A 1 462 ? 28.20959  -15.40710 -32.33161 1.000 58.99144  ? 462 TYR A CE1 1 
ATOM   3513 C  CE2 . TYR A 1 462 ? 28.48452  -17.23152 -30.80907 1.000 80.00108  ? 462 TYR A CE2 1 
ATOM   3514 C  CZ  . TYR A 1 462 ? 28.21486  -16.76190 -32.07849 1.000 79.74405  ? 462 TYR A CZ  1 
ATOM   3515 O  OH  . TYR A 1 462 ? 27.95238  -17.64963 -33.09742 1.000 71.83050  ? 462 TYR A OH  1 
ATOM   3516 N  N   . VAL A 1 463 ? 30.65438  -11.73905 -30.38370 1.000 58.99390  ? 463 VAL A N   1 
ATOM   3517 C  CA  . VAL A 1 463 ? 31.06814  -11.10383 -31.63318 1.000 59.35642  ? 463 VAL A CA  1 
ATOM   3518 C  C   . VAL A 1 463 ? 32.58754  -11.01661 -31.70941 1.000 65.17279  ? 463 VAL A C   1 
ATOM   3519 O  O   . VAL A 1 463 ? 33.18486  -11.24527 -32.76821 1.000 59.14204  ? 463 VAL A O   1 
ATOM   3520 C  CB  . VAL A 1 463 ? 30.40244  -9.72129  -31.77502 1.000 60.11955  ? 463 VAL A CB  1 
ATOM   3521 C  CG1 . VAL A 1 463 ? 31.03946  -8.92620  -32.90620 1.000 56.36224  ? 463 VAL A CG1 1 
ATOM   3522 C  CG2 . VAL A 1 463 ? 28.90832  -9.88071  -32.01759 1.000 50.31382  ? 463 VAL A CG2 1 
ATOM   3523 N  N   . ALA A 1 464 ? 33.23785  -10.69428 -30.58890 1.000 61.56394  ? 464 ALA A N   1 
ATOM   3524 C  CA  . ALA A 1 464 ? 34.69740  -10.67831 -30.56176 1.000 65.32025  ? 464 ALA A CA  1 
ATOM   3525 C  C   . ALA A 1 464 ? 35.26996  -12.06734 -30.81846 1.000 69.17539  ? 464 ALA A C   1 
ATOM   3526 O  O   . ALA A 1 464 ? 36.27523  -12.21270 -31.52515 1.000 65.50677  ? 464 ALA A O   1 
ATOM   3527 C  CB  . ALA A 1 464 ? 35.19109  -10.13170 -29.22373 1.000 61.08632  ? 464 ALA A CB  1 
ATOM   3528 N  N   . LEU A 1 465 ? 34.64065  -13.10055 -30.25090 1.000 60.30873  ? 465 LEU A N   1 
ATOM   3529 C  CA  . LEU A 1 465 ? 35.13924  -14.46317 -30.41232 1.000 67.33251  ? 465 LEU A CA  1 
ATOM   3530 C  C   . LEU A 1 465 ? 35.11868  -14.89873 -31.87198 1.000 76.31085  ? 465 LEU A C   1 
ATOM   3531 O  O   . LEU A 1 465 ? 36.06122  -15.54094 -32.34714 1.000 70.51660  ? 465 LEU A O   1 
ATOM   3532 C  CB  . LEU A 1 465 ? 34.31089  -15.42737 -29.56201 1.000 62.40107  ? 465 LEU A CB  1 
ATOM   3533 C  CG  . LEU A 1 465 ? 34.46255  -16.91915 -29.87436 1.000 46.88158  ? 465 LEU A CG  1 
ATOM   3534 C  CD1 . LEU A 1 465 ? 35.81704  -17.44380 -29.41702 1.000 51.54073  ? 465 LEU A CD1 1 
ATOM   3535 C  CD2 . LEU A 1 465 ? 33.32830  -17.72088 -29.25288 1.000 49.59127  ? 465 LEU A CD2 1 
ATOM   3536 N  N   . MET A 1 466 ? 34.05670  -14.55720 -32.60131 1.000 76.06701  ? 466 MET A N   1 
ATOM   3537 C  CA  . MET A 1 466 ? 33.86884  -15.05535 -33.95717 1.000 64.30392  ? 466 MET A CA  1 
ATOM   3538 C  C   . MET A 1 466 ? 34.36341  -14.10204 -35.03776 1.000 72.43973  ? 466 MET A C   1 
ATOM   3539 O  O   . MET A 1 466 ? 34.58153  -14.54267 -36.17090 1.000 77.11312  ? 466 MET A O   1 
ATOM   3540 C  CB  . MET A 1 466 ? 32.38622  -15.35950 -34.20601 1.000 54.60950  ? 466 MET A CB  1 
ATOM   3541 C  CG  . MET A 1 466 ? 31.72439  -16.18415 -33.11378 1.000 63.62434  ? 466 MET A CG  1 
ATOM   3542 S  SD  . MET A 1 466 ? 32.15359  -17.93140 -33.18634 1.000 69.26544  ? 466 MET A SD  1 
ATOM   3543 C  CE  . MET A 1 466 ? 31.44408  -18.37247 -34.76975 1.000 68.71298  ? 466 MET A CE  1 
ATOM   3544 N  N   . ASP A 1 467 ? 34.55020  -12.81757 -34.72563 1.000 61.77781  ? 467 ASP A N   1 
ATOM   3545 C  CA  . ASP A 1 467 ? 34.87776  -11.82498 -35.73908 1.000 60.58508  ? 467 ASP A CA  1 
ATOM   3546 C  C   . ASP A 1 467 ? 36.17942  -11.07474 -35.49938 1.000 62.58670  ? 467 ASP A C   1 
ATOM   3547 O  O   . ASP A 1 467 ? 36.73613  -10.53195 -36.46010 1.000 64.36007  ? 467 ASP A O   1 
ATOM   3548 C  CB  . ASP A 1 467 ? 33.74747  -10.78851 -35.86302 1.000 60.88015  ? 467 ASP A CB  1 
ATOM   3549 C  CG  . ASP A 1 467 ? 32.41579  -11.41103 -36.23488 1.000 56.58509  ? 467 ASP A CG  1 
ATOM   3550 O  OD1 . ASP A 1 467 ? 32.39284  -12.27435 -37.13802 1.000 75.12026  ? 467 ASP A OD1 1 
ATOM   3551 O  OD2 . ASP A 1 467 ? 31.39260  -11.02949 -35.62619 1.000 43.75323  ? 467 ASP A OD2 1 
ATOM   3552 N  N   . LEU A 1 468 ? 36.67919  -11.01903 -34.26491 1.000 51.93308  ? 468 LEU A N   1 
ATOM   3553 C  CA  . LEU A 1 468 ? 37.82170  -10.17493 -33.94855 1.000 60.92860  ? 468 LEU A CA  1 
ATOM   3554 C  C   . LEU A 1 468 ? 39.10858  -10.94233 -33.68053 1.000 62.79271  ? 468 LEU A C   1 
ATOM   3555 O  O   . LEU A 1 468 ? 40.16793  -10.31470 -33.57849 1.000 55.73070  ? 468 LEU A O   1 
ATOM   3556 C  CB  . LEU A 1 468 ? 37.50253  -9.28200  -32.73966 1.000 69.00405  ? 468 LEU A CB  1 
ATOM   3557 C  CG  . LEU A 1 468 ? 36.33247  -8.30867  -32.91868 1.000 64.22531  ? 468 LEU A CG  1 
ATOM   3558 C  CD1 . LEU A 1 468 ? 36.20563  -7.38805  -31.71549 1.000 38.88083  ? 468 LEU A CD1 1 
ATOM   3559 C  CD2 . LEU A 1 468 ? 36.47488  -7.50415  -34.20178 1.000 35.44860  ? 468 LEU A CD2 1 
ATOM   3560 N  N   . CYS A 1 469 ? 39.05796  -12.26235 -33.56492 1.000 67.89856  ? 469 CYS A N   1 
ATOM   3561 C  CA  . CYS A 1 469 ? 40.25902  -13.06997 -33.40176 1.000 62.75881  ? 469 CYS A CA  1 
ATOM   3562 C  C   . CYS A 1 469 ? 40.29903  -14.14265 -34.48847 1.000 67.03444  ? 469 CYS A C   1 
ATOM   3563 O  O   . CYS A 1 469 ? 39.36787  -14.28891 -35.28289 1.000 67.49114  ? 469 CYS A O   1 
ATOM   3564 C  CB  . CYS A 1 469 ? 40.32131  -13.68373 -31.99877 1.000 53.26379  ? 469 CYS A CB  1 
ATOM   3565 S  SG  . CYS A 1 469 ? 38.95398  -14.78480 -31.59245 1.000 75.76618  ? 469 CYS A SG  1 
ATOM   3566 N  N   . GLY A 1 470 ? 41.39674  -14.89641 -34.52016 1.000 69.67436  ? 470 GLY A N   1 
ATOM   3567 C  CA  . GLY A 1 470 ? 41.63110  -15.85017 -35.58184 1.000 71.43859  ? 470 GLY A CA  1 
ATOM   3568 C  C   . GLY A 1 470 ? 40.89868  -17.16661 -35.39535 1.000 78.36073  ? 470 GLY A C   1 
ATOM   3569 O  O   . GLY A 1 470 ? 40.20407  -17.40746 -34.40818 1.000 68.47760  ? 470 GLY A O   1 
ATOM   3570 N  N   . ARG A 1 471 ? 41.07182  -18.04181 -36.39075 1.000 75.85817  ? 471 ARG A N   1 
ATOM   3571 C  CA  . ARG A 1 471 ? 40.47803  -19.37345 -36.36752 1.000 65.39930  ? 471 ARG A CA  1 
ATOM   3572 C  C   . ARG A 1 471 ? 41.18456  -20.30992 -35.39160 1.000 72.17765  ? 471 ARG A C   1 
ATOM   3573 O  O   . ARG A 1 471 ? 40.61686  -21.34320 -35.02110 1.000 73.26208  ? 471 ARG A O   1 
ATOM   3574 C  CB  . ARG A 1 471 ? 40.49457  -19.96529 -37.78282 1.000 73.61125  ? 471 ARG A CB  1 
ATOM   3575 C  CG  . ARG A 1 471 ? 39.78753  -21.30172 -37.94125 1.000 76.38523  ? 471 ARG A CG  1 
ATOM   3576 C  CD  . ARG A 1 471 ? 40.10533  -21.92674 -39.28778 1.000 62.32634  ? 471 ARG A CD  1 
ATOM   3577 N  NE  . ARG A 1 471 ? 39.61672  -23.29914 -39.37850 1.000 71.67497  ? 471 ARG A NE  1 
ATOM   3578 C  CZ  . ARG A 1 471 ? 40.35564  -24.37504 -39.14395 1.000 66.78075  ? 471 ARG A CZ  1 
ATOM   3579 N  NH1 . ARG A 1 471 ? 41.63338  -24.27861 -38.81369 1.000 64.80064  ? 471 ARG A NH1 1 
ATOM   3580 N  NH2 . ARG A 1 471 ? 39.79886  -25.57717 -39.24500 1.000 65.71231  ? 471 ARG A NH2 1 
ATOM   3581 N  N   . ASP A 1 472 ? 42.39563  -19.96450 -34.94834 1.000 69.37981  ? 472 ASP A N   1 
ATOM   3582 C  CA  . ASP A 1 472 ? 43.15297  -20.77756 -34.00443 1.000 66.62861  ? 472 ASP A CA  1 
ATOM   3583 C  C   . ASP A 1 472 ? 43.21542  -20.14641 -32.61663 1.000 73.77866  ? 472 ASP A C   1 
ATOM   3584 O  O   . ASP A 1 472 ? 44.17325  -20.38897 -31.87321 1.000 84.81564  ? 472 ASP A O   1 
ATOM   3585 C  CB  . ASP A 1 472 ? 44.56725  -21.02997 -34.53759 1.000 64.96773  ? 472 ASP A CB  1 
ATOM   3586 C  CG  . ASP A 1 472 ? 44.57900  -21.87754 -35.79674 1.000 82.79335  ? 472 ASP A CG  1 
ATOM   3587 O  OD1 . ASP A 1 472 ? 43.56736  -22.56099 -36.06950 1.000 78.23255  ? 472 ASP A OD1 1 
ATOM   3588 O  OD2 . ASP A 1 472 ? 45.60353  -21.86230 -36.51512 1.000 91.29662  ? 472 ASP A OD2 1 
ATOM   3589 N  N   . THR A 1 473 ? 42.21859  -19.33308 -32.25799 1.000 67.37295  ? 473 THR A N   1 
ATOM   3590 C  CA  . THR A 1 473 ? 42.23172  -18.55733 -31.01538 1.000 62.67645  ? 473 THR A CA  1 
ATOM   3591 C  C   . THR A 1 473 ? 40.80947  -18.43997 -30.48990 1.000 60.81198  ? 473 THR A C   1 
ATOM   3592 O  O   . THR A 1 473 ? 40.00891  -17.67247 -31.04106 1.000 59.49920  ? 473 THR A O   1 
ATOM   3593 C  CB  . THR A 1 473 ? 42.81989  -17.16714 -31.25307 1.000 56.53041  ? 473 THR A CB  1 
ATOM   3594 O  OG1 . THR A 1 473 ? 44.10304  -17.28579 -31.89164 1.000 49.56539  ? 473 THR A OG1 1 
ATOM   3595 C  CG2 . THR A 1 473 ? 42.98615  -16.41421 -29.94340 1.000 73.20088  ? 473 THR A CG2 1 
ATOM   3596 N  N   . ALA A 1 474 ? 40.48025  -19.21779 -29.45339 1.000 63.59869  ? 474 ALA A N   1 
ATOM   3597 C  CA  . ALA A 1 474 ? 39.16602  -19.11017 -28.82366 1.000 60.45633  ? 474 ALA A CA  1 
ATOM   3598 C  C   . ALA A 1 474 ? 39.21667  -18.75347 -27.34307 1.000 75.54327  ? 474 ALA A C   1 
ATOM   3599 O  O   . ALA A 1 474 ? 38.82504  -17.63452 -26.98862 1.000 80.62424  ? 474 ALA A O   1 
ATOM   3600 C  CB  . ALA A 1 474 ? 38.40216  -20.41368 -29.06073 1.000 62.13653  ? 474 ALA A CB  1 
ATOM   3601 N  N   . LEU A 1 475 ? 39.76873  -19.61852 -26.47758 1.000 69.63667  ? 475 LEU A N   1 
ATOM   3602 C  CA  . LEU A 1 475 ? 39.57755  -19.40948 -25.03759 1.000 57.84691  ? 475 LEU A CA  1 
ATOM   3603 C  C   . LEU A 1 475 ? 40.71522  -18.64784 -24.36791 1.000 63.22407  ? 475 LEU A C   1 
ATOM   3604 O  O   . LEU A 1 475 ? 40.48367  -17.93135 -23.38819 1.000 79.71459  ? 475 LEU A O   1 
ATOM   3605 C  CB  . LEU A 1 475 ? 39.39575  -20.74725 -24.30881 1.000 59.76875  ? 475 LEU A CB  1 
ATOM   3606 C  CG  . LEU A 1 475 ? 38.75320  -20.65466 -22.92762 1.000 56.12363  ? 475 LEU A CG  1 
ATOM   3607 C  CD1 . LEU A 1 475 ? 37.24097  -20.44494 -23.01683 1.000 48.68367  ? 475 LEU A CD1 1 
ATOM   3608 C  CD2 . LEU A 1 475 ? 39.07485  -21.88426 -22.09507 1.000 63.15637  ? 475 LEU A CD2 1 
ATOM   3609 N  N   . THR A 1 476 ? 41.94489  -18.82241 -24.84870 1.000 58.61390  ? 476 THR A N   1 
ATOM   3610 C  CA  . THR A 1 476 ? 43.03841  -17.94086 -24.45014 1.000 70.45274  ? 476 THR A CA  1 
ATOM   3611 C  C   . THR A 1 476 ? 42.66051  -16.47948 -24.66143 1.000 67.24959  ? 476 THR A C   1 
ATOM   3612 O  O   . THR A 1 476 ? 42.96122  -15.61516 -23.82803 1.000 73.43538  ? 476 THR A O   1 
ATOM   3613 C  CB  . THR A 1 476 ? 44.29050  -18.29531 -25.25684 1.000 69.36105  ? 476 THR A CB  1 
ATOM   3614 O  OG1 . THR A 1 476 ? 43.92082  -18.43953 -26.63408 1.000 84.69306  ? 476 THR A OG1 1 
ATOM   3615 C  CG2 . THR A 1 476 ? 44.87754  -19.60575 -24.76234 1.000 59.44988  ? 476 THR A CG2 1 
ATOM   3616 N  N   . PHE A 1 477 ? 41.98573  -16.19470 -25.77639 1.000 72.44769  ? 477 PHE A N   1 
ATOM   3617 C  CA  . PHE A 1 477 ? 41.56339  -14.83241 -26.08832 1.000 74.53445  ? 477 PHE A CA  1 
ATOM   3618 C  C   . PHE A 1 477 ? 40.52307  -14.32714 -25.09302 1.000 76.29267  ? 477 PHE A C   1 
ATOM   3619 O  O   . PHE A 1 477 ? 40.63738  -13.21175 -24.57017 1.000 68.77970  ? 477 PHE A O   1 
ATOM   3620 C  CB  . PHE A 1 477 ? 41.02675  -14.79367 -27.52272 1.000 70.55961  ? 477 PHE A CB  1 
ATOM   3621 C  CG  . PHE A 1 477 ? 40.26043  -13.54863 -27.87208 1.000 65.99551  ? 477 PHE A CG  1 
ATOM   3622 C  CD1 . PHE A 1 477 ? 40.90231  -12.32668 -27.99539 1.000 57.58286  ? 477 PHE A CD1 1 
ATOM   3623 C  CD2 . PHE A 1 477 ? 38.89739  -13.61033 -28.12090 1.000 63.02991  ? 477 PHE A CD2 1 
ATOM   3624 C  CE1 . PHE A 1 477 ? 40.19403  -11.18832 -28.33154 1.000 68.26729  ? 477 PHE A CE1 1 
ATOM   3625 C  CE2 . PHE A 1 477 ? 38.18524  -12.47782 -28.45768 1.000 60.04289  ? 477 PHE A CE2 1 
ATOM   3626 C  CZ  . PHE A 1 477 ? 38.83406  -11.26500 -28.56321 1.000 66.39944  ? 477 PHE A CZ  1 
ATOM   3627 N  N   . LEU A 1 478 ? 39.49846  -15.13906 -24.81671 1.000 66.88163  ? 478 LEU A N   1 
ATOM   3628 C  CA  . LEU A 1 478 ? 38.42522  -14.70222 -23.92741 1.000 70.19778  ? 478 LEU A CA  1 
ATOM   3629 C  C   . LEU A 1 478 ? 38.91155  -14.54014 -22.49042 1.000 78.30656  ? 478 LEU A C   1 
ATOM   3630 O  O   . LEU A 1 478 ? 38.52177  -13.58905 -21.80221 1.000 73.36875  ? 478 LEU A O   1 
ATOM   3631 C  CB  . LEU A 1 478 ? 37.25982  -15.68803 -23.99079 1.000 66.51076  ? 478 LEU A CB  1 
ATOM   3632 C  CG  . LEU A 1 478 ? 36.56998  -15.80512 -25.35047 1.000 62.82058  ? 478 LEU A CG  1 
ATOM   3633 C  CD1 . LEU A 1 478 ? 35.39580  -16.76656 -25.27839 1.000 56.73583  ? 478 LEU A CD1 1 
ATOM   3634 C  CD2 . LEU A 1 478 ? 36.11714  -14.43639 -25.82838 1.000 65.74273  ? 478 LEU A CD2 1 
ATOM   3635 N  N   . LYS A 1 479 ? 39.75027  -15.46428 -22.01451 1.000 72.43615  ? 479 LYS A N   1 
ATOM   3636 C  CA  . LYS A 1 479 ? 40.23075  -15.38711 -20.63787 1.000 61.53464  ? 479 LYS A CA  1 
ATOM   3637 C  C   . LYS A 1 479 ? 41.09849  -14.15338 -20.42564 1.000 73.49562  ? 479 LYS A C   1 
ATOM   3638 O  O   . LYS A 1 479 ? 40.99821  -13.48383 -19.38883 1.000 71.30287  ? 479 LYS A O   1 
ATOM   3639 C  CB  . LYS A 1 479 ? 40.99920  -16.65956 -20.27905 1.000 63.49003  ? 479 LYS A CB  1 
ATOM   3640 C  CG  . LYS A 1 479 ? 41.20456  -16.87086 -18.78761 1.000 73.65011  ? 479 LYS A CG  1 
ATOM   3641 C  CD  . LYS A 1 479 ? 41.88137  -18.20356 -18.51417 1.000 64.47119  ? 479 LYS A CD  1 
ATOM   3642 C  CE  . LYS A 1 479 ? 42.03514  -18.45061 -17.02429 1.000 55.65829  ? 479 LYS A CE  1 
ATOM   3643 N  NZ  . LYS A 1 479 ? 42.84713  -19.66876 -16.75815 1.000 59.10493  ? 479 LYS A NZ  1 
ATOM   3644 N  N   . GLN A 1 480 ? 41.95649  -13.83623 -21.40025 1.000 69.56938  ? 480 GLN A N   1 
ATOM   3645 C  CA  . GLN A 1 480 ? 42.76527  -12.62659 -21.30689 1.000 62.51601  ? 480 GLN A CA  1 
ATOM   3646 C  C   . GLN A 1 480 ? 41.89971  -11.37302 -21.30093 1.000 67.62410  ? 480 GLN A C   1 
ATOM   3647 O  O   . GLN A 1 480 ? 42.25712  -10.37910 -20.65993 1.000 78.63171  ? 480 GLN A O   1 
ATOM   3648 C  CB  . GLN A 1 480 ? 43.76772  -12.57422 -22.46158 1.000 62.19484  ? 480 GLN A CB  1 
ATOM   3649 C  CG  . GLN A 1 480 ? 44.79295  -11.45641 -22.34485 1.000 71.78910  ? 480 GLN A CG  1 
ATOM   3650 C  CD  . GLN A 1 480 ? 45.80888  -11.70691 -21.24672 1.000 82.47261  ? 480 GLN A CD  1 
ATOM   3651 O  OE1 . GLN A 1 480 ? 46.24603  -12.83822 -21.03649 1.000 68.09075  ? 480 GLN A OE1 1 
ATOM   3652 N  NE2 . GLN A 1 480 ? 46.18854  -10.64974 -20.53847 1.000 82.74554  ? 480 GLN A NE2 1 
ATOM   3653 N  N   . LEU A 1 481 ? 40.76737  -11.39331 -22.00967 1.000 62.71272  ? 481 LEU A N   1 
ATOM   3654 C  CA  . LEU A 1 481 ? 39.84385  -10.26216 -21.96124 1.000 67.56365  ? 481 LEU A CA  1 
ATOM   3655 C  C   . LEU A 1 481 ? 39.33172  -10.03451 -20.54592 1.000 71.71714  ? 481 LEU A C   1 
ATOM   3656 O  O   . LEU A 1 481 ? 39.30760  -8.89910  -20.05665 1.000 72.01423  ? 481 LEU A O   1 
ATOM   3657 C  CB  . LEU A 1 481 ? 38.66949  -10.49209 -22.91367 1.000 58.32016  ? 481 LEU A CB  1 
ATOM   3658 C  CG  . LEU A 1 481 ? 38.91044  -10.40673 -24.41935 1.000 56.34900  ? 481 LEU A CG  1 
ATOM   3659 C  CD1 . LEU A 1 481 ? 37.59946  -10.60102 -25.16463 1.000 51.21179  ? 481 LEU A CD1 1 
ATOM   3660 C  CD2 . LEU A 1 481 ? 39.55397  -9.08047  -24.79165 1.000 50.28763  ? 481 LEU A CD2 1 
ATOM   3661 N  N   . ALA A 1 482 ? 38.90992  -11.10945 -19.87472 1.000 58.80235  ? 482 ALA A N   1 
ATOM   3662 C  CA  . ALA A 1 482 ? 38.40216  -10.98216 -18.51283 1.000 58.52714  ? 482 ALA A CA  1 
ATOM   3663 C  C   . ALA A 1 482 ? 39.48503  -10.48467 -17.56423 1.000 71.61689  ? 482 ALA A C   1 
ATOM   3664 O  O   . ALA A 1 482 ? 39.21673  -9.66917  -16.67364 1.000 76.21977  ? 482 ALA A O   1 
ATOM   3665 C  CB  . ALA A 1 482 ? 37.84098  -12.31996 -18.03520 1.000 56.47657  ? 482 ALA A CB  1 
ATOM   3666 N  N   . LEU A 1 483 ? 40.71477  -10.97357 -17.73100 1.000 64.44732  ? 483 LEU A N   1 
ATOM   3667 C  CA  . LEU A 1 483 ? 41.80877  -10.52017 -16.87891 1.000 63.30301  ? 483 LEU A CA  1 
ATOM   3668 C  C   . LEU A 1 483 ? 42.16887  -9.06666  -17.16145 1.000 67.35633  ? 483 LEU A C   1 
ATOM   3669 O  O   . LEU A 1 483 ? 42.52623  -8.32068  -16.24184 1.000 80.33278  ? 483 LEU A O   1 
ATOM   3670 C  CB  . LEU A 1 483 ? 43.02384  -11.42781 -17.06765 1.000 63.88925  ? 483 LEU A CB  1 
ATOM   3671 C  CG  . LEU A 1 483 ? 42.90159  -12.80386 -16.41051 1.000 76.39689  ? 483 LEU A CG  1 
ATOM   3672 C  CD1 . LEU A 1 483 ? 43.82714  -13.80844 -17.07668 1.000 78.75146  ? 483 LEU A CD1 1 
ATOM   3673 C  CD2 . LEU A 1 483 ? 43.19819  -12.70593 -14.92105 1.000 58.59825  ? 483 LEU A CD2 1 
ATOM   3674 N  N   . ASN A 1 484 ? 42.08172  -8.64566  -18.42554 1.000 69.09507  ? 484 ASN A N   1 
ATOM   3675 C  CA  . ASN A 1 484 ? 42.40693  -7.26530  -18.76768 1.000 70.24279  ? 484 ASN A CA  1 
ATOM   3676 C  C   . ASN A 1 484 ? 41.35814  -6.29228  -18.24773 1.000 71.29756  ? 484 ASN A C   1 
ATOM   3677 O  O   . ASN A 1 484 ? 41.67510  -5.12673  -17.98798 1.000 66.22236  ? 484 ASN A O   1 
ATOM   3678 C  CB  . ASN A 1 484 ? 42.56628  -7.11756  -20.28049 1.000 64.94769  ? 484 ASN A CB  1 
ATOM   3679 C  CG  . ASN A 1 484 ? 43.92207  -7.58289  -20.77027 1.000 71.63803  ? 484 ASN A CG  1 
ATOM   3680 O  OD1 . ASN A 1 484 ? 44.70678  -8.15370  -20.01335 1.000 88.17274  ? 484 ASN A OD1 1 
ATOM   3681 N  ND2 . ASN A 1 484 ? 44.20617  -7.33807  -22.04340 1.000 70.61885  ? 484 ASN A ND2 1 
ATOM   3682 N  N   . SER A 1 485 ? 40.11024  -6.74220  -18.09182 1.000 66.33929  ? 485 SER A N   1 
ATOM   3683 C  CA  . SER A 1 485 ? 39.08271  -5.87273  -17.53148 1.000 58.68732  ? 485 SER A CA  1 
ATOM   3684 C  C   . SER A 1 485 ? 39.32893  -5.58021  -16.05778 1.000 67.51523  ? 485 SER A C   1 
ATOM   3685 O  O   . SER A 1 485 ? 38.80961  -4.58625  -15.53939 1.000 69.62295  ? 485 SER A O   1 
ATOM   3686 C  CB  . SER A 1 485 ? 37.69732  -6.49027  -17.71980 1.000 50.80886  ? 485 SER A CB  1 
ATOM   3687 O  OG  . SER A 1 485 ? 37.48635  -7.55075  -16.80699 1.000 61.27881  ? 485 SER A OG  1 
ATOM   3688 N  N   . ILE A 1 486 ? 40.10547  -6.41959  -15.37792 1.000 67.31919  ? 486 ILE A N   1 
ATOM   3689 C  CA  . ILE A 1 486 ? 40.49021  -6.15891  -13.99581 1.000 69.33594  ? 486 ILE A CA  1 
ATOM   3690 C  C   . ILE A 1 486 ? 41.81297  -5.40709  -13.92777 1.000 70.28909  ? 486 ILE A C   1 
ATOM   3691 O  O   . ILE A 1 486 ? 41.96846  -4.48376  -13.12419 1.000 75.48902  ? 486 ILE A O   1 
ATOM   3692 C  CB  . ILE A 1 486 ? 40.55512  -7.48395  -13.20899 1.000 57.62438  ? 486 ILE A CB  1 
ATOM   3693 C  CG1 . ILE A 1 486 ? 39.21746  -8.22319  -13.28402 1.000 49.78738  ? 486 ILE A CG1 1 
ATOM   3694 C  CG2 . ILE A 1 486 ? 40.95013  -7.23109  -11.76033 1.000 51.34406  ? 486 ILE A CG2 1 
ATOM   3695 C  CD1 . ILE A 1 486 ? 39.26030  -9.61138  -12.69275 1.000 60.22451  ? 486 ILE A CD1 1 
ATOM   3696 N  N   . ARG A 1 487 ? 42.77835  -5.78725  -14.76842 1.000 60.08831  ? 487 ARG A N   1 
ATOM   3697 C  CA  . ARG A 1 487 ? 44.08439  -5.13655  -14.73883 1.000 64.52519  ? 487 ARG A CA  1 
ATOM   3698 C  C   . ARG A 1 487 ? 43.98862  -3.67853  -15.16416 1.000 64.41191  ? 487 ARG A C   1 
ATOM   3699 O  O   . ARG A 1 487 ? 44.57540  -2.79586  -14.52734 1.000 77.53894  ? 487 ARG A O   1 
ATOM   3700 C  CB  . ARG A 1 487 ? 45.07146  -5.87905  -15.63814 1.000 69.37971  ? 487 ARG A CB  1 
ATOM   3701 C  CG  . ARG A 1 487 ? 46.37857  -5.12382  -15.80725 1.000 67.82109  ? 487 ARG A CG  1 
ATOM   3702 C  CD  . ARG A 1 487 ? 47.33327  -5.80459  -16.76412 1.000 75.79414  ? 487 ARG A CD  1 
ATOM   3703 N  NE  . ARG A 1 487 ? 48.61562  -5.10951  -16.78361 1.000 82.81654  ? 487 ARG A NE  1 
ATOM   3704 C  CZ  . ARG A 1 487 ? 49.56561  -5.30802  -17.68562 1.000 87.07025  ? 487 ARG A CZ  1 
ATOM   3705 N  NH1 . ARG A 1 487 ? 49.42071  -6.19210  -18.65902 1.000 81.65635  ? 487 ARG A NH1 1 
ATOM   3706 N  NH2 . ARG A 1 487 ? 50.68561  -4.59551  -17.61377 1.000 85.89305  ? 487 ARG A NH2 1 
ATOM   3707 N  N   . TYR A 1 488 ? 43.25963  -3.40486  -16.24418 1.000 75.28563  ? 488 TYR A N   1 
ATOM   3708 C  CA  . TYR A 1 488 ? 43.14674  -2.05659  -16.78168 1.000 68.00621  ? 488 TYR A CA  1 
ATOM   3709 C  C   . TYR A 1 488 ? 41.89193  -1.34393  -16.29323 1.000 67.99927  ? 488 TYR A C   1 
ATOM   3710 O  O   . TYR A 1 488 ? 41.34508  -0.49159  -16.99946 1.000 64.81616  ? 488 TYR A O   1 
ATOM   3711 C  CB  . TYR A 1 488 ? 43.19688  -2.09344  -18.30774 1.000 62.62596  ? 488 TYR A CB  1 
ATOM   3712 C  CG  . TYR A 1 488 ? 44.51289  -2.61083  -18.84287 1.000 63.32018  ? 488 TYR A CG  1 
ATOM   3713 C  CD1 . TYR A 1 488 ? 45.66171  -1.83094  -18.78153 1.000 65.71500  ? 488 TYR A CD1 1 
ATOM   3714 C  CD2 . TYR A 1 488 ? 44.60987  -3.87817  -19.40243 1.000 64.88722  ? 488 TYR A CD2 1 
ATOM   3715 C  CE1 . TYR A 1 488 ? 46.86889  -2.29779  -19.26513 1.000 67.81378  ? 488 TYR A CE1 1 
ATOM   3716 C  CE2 . TYR A 1 488 ? 45.81326  -4.35415  -19.88968 1.000 73.86447  ? 488 TYR A CE2 1 
ATOM   3717 C  CZ  . TYR A 1 488 ? 46.93945  -3.55888  -19.81857 1.000 74.07838  ? 488 TYR A CZ  1 
ATOM   3718 O  OH  . TYR A 1 488 ? 48.14156  -4.02295  -20.30077 1.000 80.04758  ? 488 TYR A OH  1 
ATOM   3719 N  N   . SER A 1 489 ? 41.42392  -1.68079  -15.09471 1.000 72.45313  ? 489 SER A N   1 
ATOM   3720 C  CA  . SER A 1 489 ? 40.31906  -0.97145  -14.47447 1.000 66.64162  ? 489 SER A CA  1 
ATOM   3721 C  C   . SER A 1 489 ? 40.85969  0.17040   -13.61732 1.000 62.96159  ? 489 SER A C   1 
ATOM   3722 O  O   . SER A 1 489 ? 42.06358  0.43445   -13.57365 1.000 62.66424  ? 489 SER A O   1 
ATOM   3723 C  CB  . SER A 1 489 ? 39.46763  -1.92683  -13.64089 1.000 66.78406  ? 489 SER A CB  1 
ATOM   3724 O  OG  . SER A 1 489 ? 40.19326  -2.39650  -12.51952 1.000 74.45835  ? 489 SER A OG  1 
ATOM   3725 N  N   . ALA A 1 490 ? 39.95758  0.85939   -12.92282 1.000 71.52919  ? 490 ALA A N   1 
ATOM   3726 C  CA  . ALA A 1 490 ? 40.32347  1.98546   -12.07722 1.000 72.10873  ? 490 ALA A CA  1 
ATOM   3727 C  C   . ALA A 1 490 ? 40.37428  1.62116   -10.59888 1.000 72.16160  ? 490 ALA A C   1 
ATOM   3728 O  O   . ALA A 1 490 ? 40.48858  2.51531   -9.75426  1.000 79.64314  ? 490 ALA A O   1 
ATOM   3729 C  CB  . ALA A 1 490 ? 39.35342  3.14740   -12.29907 1.000 58.22176  ? 490 ALA A CB  1 
ATOM   3730 N  N   . MET A 1 491 ? 40.29363  0.33625   -10.26746 1.000 76.69396  ? 491 MET A N   1 
ATOM   3731 C  CA  . MET A 1 491 ? 40.40243  -0.08291  -8.88069  1.000 85.92019  ? 491 MET A CA  1 
ATOM   3732 C  C   . MET A 1 491 ? 41.82444  0.12506   -8.36840  1.000 82.60028  ? 491 MET A C   1 
ATOM   3733 O  O   . MET A 1 491 ? 42.79038  0.17424   -9.13322  1.000 76.32748  ? 491 MET A O   1 
ATOM   3734 C  CB  . MET A 1 491 ? 40.01419  -1.55350  -8.72805  1.000 75.55943  ? 491 MET A CB  1 
ATOM   3735 C  CG  . MET A 1 491 ? 38.52821  -1.82620  -8.83905  1.000 72.61551  ? 491 MET A CG  1 
ATOM   3736 S  SD  . MET A 1 491 ? 38.13259  -3.57906  -8.68284  1.000 76.37876  ? 491 MET A SD  1 
ATOM   3737 C  CE  . MET A 1 491 ? 38.97178  -4.24669  -10.11673 1.000 70.56831  ? 491 MET A CE  1 
ATOM   3738 N  N   . SER A 1 492 ? 41.94332  0.25303   -7.05056  1.000 78.12215  ? 492 SER A N   1 
ATOM   3739 C  CA  . SER A 1 492 ? 43.25558  0.29459   -6.42600  1.000 74.96129  ? 492 SER A CA  1 
ATOM   3740 C  C   . SER A 1 492 ? 43.94918  -1.04817  -6.61189  1.000 82.10871  ? 492 SER A C   1 
ATOM   3741 O  O   . SER A 1 492 ? 43.30261  -2.07930  -6.81078  1.000 86.31187  ? 492 SER A O   1 
ATOM   3742 C  CB  . SER A 1 492 ? 43.13790  0.63086   -4.94143  1.000 78.00764  ? 492 SER A CB  1 
ATOM   3743 O  OG  . SER A 1 492 ? 42.35607  -0.34027  -4.26892  1.000 80.43395  ? 492 SER A OG  1 
ATOM   3744 N  N   . ASP A 1 493 ? 45.28448  -1.02436  -6.57837  1.000 78.82863  ? 493 ASP A N   1 
ATOM   3745 C  CA  . ASP A 1 493 ? 46.04628  -2.26265  -6.71591  1.000 80.53095  ? 493 ASP A CA  1 
ATOM   3746 C  C   . ASP A 1 493 ? 45.60441  -3.29480  -5.68700  1.000 84.05239  ? 493 ASP A C   1 
ATOM   3747 O  O   . ASP A 1 493 ? 45.54563  -4.49461  -5.98147  1.000 93.97660  ? 493 ASP A O   1 
ATOM   3748 C  CB  . ASP A 1 493 ? 47.54177  -1.97817  -6.57973  1.000 80.19227  ? 493 ASP A CB  1 
ATOM   3749 C  CG  . ASP A 1 493 ? 48.03136  -0.94466  -7.57287  1.000 95.52675  ? 493 ASP A CG  1 
ATOM   3750 O  OD1 . ASP A 1 493 ? 47.49455  -0.89128  -8.69965  1.000 101.52627 ? 493 ASP A OD1 1 
ATOM   3751 O  OD2 . ASP A 1 493 ? 48.95734  -0.18402  -7.21990  1.000 103.34641 ? 493 ASP A OD2 1 
ATOM   3752 N  N   . THR A 1 494 ? 45.29485  -2.84168  -4.46970  1.000 80.55962  ? 494 THR A N   1 
ATOM   3753 C  CA  . THR A 1 494 ? 44.75724  -3.73516  -3.44890  1.000 77.09557  ? 494 THR A CA  1 
ATOM   3754 C  C   . THR A 1 494 ? 43.41940  -4.32052  -3.88579  1.000 86.35109  ? 494 THR A C   1 
ATOM   3755 O  O   . THR A 1 494 ? 43.18694  -5.53000  -3.76612  1.000 80.12162  ? 494 THR A O   1 
ATOM   3756 C  CB  . THR A 1 494 ? 44.60630  -2.98083  -2.12884  1.000 81.58067  ? 494 THR A CB  1 
ATOM   3757 O  OG1 . THR A 1 494 ? 45.72087  -2.09828  -1.95679  1.000 84.88939  ? 494 THR A OG1 1 
ATOM   3758 C  CG2 . THR A 1 494 ? 44.55950  -3.95468  -0.96192  1.000 104.83620 ? 494 THR A CG2 1 
ATOM   3759 N  N   . GLU A 1 495 ? 42.52570  -3.46887  -4.39874  1.000 80.41318  ? 495 GLU A N   1 
ATOM   3760 C  CA  . GLU A 1 495 ? 41.22602  -3.93835  -4.87054  1.000 73.31649  ? 495 GLU A CA  1 
ATOM   3761 C  C   . GLU A 1 495 ? 41.37214  -4.93473  -6.01129  1.000 80.86108  ? 495 GLU A C   1 
ATOM   3762 O  O   . GLU A 1 495 ? 40.66867  -5.94813  -6.04888  1.000 75.93750  ? 495 GLU A O   1 
ATOM   3763 C  CB  . GLU A 1 495 ? 40.37000  -2.75618  -5.32379  1.000 71.08835  ? 495 GLU A CB  1 
ATOM   3764 C  CG  . GLU A 1 495 ? 39.56160  -2.08159  -4.23271  1.000 81.09041  ? 495 GLU A CG  1 
ATOM   3765 C  CD  . GLU A 1 495 ? 38.86002  -0.84014  -4.74555  1.000 80.31225  ? 495 GLU A CD  1 
ATOM   3766 O  OE1 . GLU A 1 495 ? 39.51068  -0.04563  -5.45646  1.000 74.31415  ? 495 GLU A OE1 1 
ATOM   3767 O  OE2 . GLU A 1 495 ? 37.65634  -0.67041  -4.46095  1.000 74.84962  ? 495 GLU A OE2 1 
ATOM   3768 N  N   . LYS A 1 496 ? 42.27492  -4.65997  -6.95464  1.000 81.20301  ? 496 LYS A N   1 
ATOM   3769 C  CA  . LYS A 1 496 ? 42.41691  -5.52163  -8.12559  1.000 71.12200  ? 496 LYS A CA  1 
ATOM   3770 C  C   . LYS A 1 496 ? 42.81591  -6.93847  -7.72959  1.000 75.88962  ? 496 LYS A C   1 
ATOM   3771 O  O   . LYS A 1 496 ? 42.32534  -7.91329  -8.31240  1.000 71.66861  ? 496 LYS A O   1 
ATOM   3772 C  CB  . LYS A 1 496 ? 43.43698  -4.92135  -9.09354  1.000 65.67389  ? 496 LYS A CB  1 
ATOM   3773 C  CG  . LYS A 1 496 ? 42.97952  -3.61369  -9.72706  1.000 70.14999  ? 496 LYS A CG  1 
ATOM   3774 C  CD  . LYS A 1 496 ? 44.00705  -3.07323  -10.70650 1.000 67.42721  ? 496 LYS A CD  1 
ATOM   3775 C  CE  . LYS A 1 496 ? 43.45269  -1.88155  -11.46578 1.000 69.03536  ? 496 LYS A CE  1 
ATOM   3776 N  NZ  . LYS A 1 496 ? 44.50835  -1.15081  -12.21615 1.000 81.72689  ? 496 LYS A NZ  1 
ATOM   3777 N  N   . VAL A 1 497 ? 43.71632  -7.07352  -6.75265  1.000 72.73424  ? 497 VAL A N   1 
ATOM   3778 C  CA  . VAL A 1 497 ? 44.07004  -8.39891  -6.24693  1.000 66.34330  ? 497 VAL A CA  1 
ATOM   3779 C  C   . VAL A 1 497 ? 42.84808  -9.07408  -5.63591  1.000 61.19922  ? 497 VAL A C   1 
ATOM   3780 O  O   . VAL A 1 497 ? 42.54379  -10.23608 -5.93176  1.000 67.96991  ? 497 VAL A O   1 
ATOM   3781 C  CB  . VAL A 1 497 ? 45.22575  -8.29927  -5.23399  1.000 67.67422  ? 497 VAL A CB  1 
ATOM   3782 C  CG1 . VAL A 1 497 ? 45.51936  -9.66186  -4.61116  1.000 47.90336  ? 497 VAL A CG1 1 
ATOM   3783 C  CG2 . VAL A 1 497 ? 46.47150  -7.73601  -5.90267  1.000 76.04412  ? 497 VAL A CG2 1 
ATOM   3784 N  N   . ALA A 1 498 ? 42.11864  -8.34714  -4.78521  1.000 58.06601  ? 498 ALA A N   1 
ATOM   3785 C  CA  . ALA A 1 498 ? 40.93904  -8.91001  -4.14019  1.000 60.46565  ? 498 ALA A CA  1 
ATOM   3786 C  C   . ALA A 1 498 ? 39.78537  -9.12268  -5.11509  1.000 66.24691  ? 498 ALA A C   1 
ATOM   3787 O  O   . ALA A 1 498 ? 38.85125  -9.87016  -4.79675  1.000 75.20269  ? 498 ALA A O   1 
ATOM   3788 C  CB  . ALA A 1 498 ? 40.49032  -8.00582  -2.99130  1.000 63.59036  ? 498 ALA A CB  1 
ATOM   3789 N  N   . ALA A 1 499 ? 39.82770  -8.48412  -6.28693  1.000 66.55671  ? 499 ALA A N   1 
ATOM   3790 C  CA  . ALA A 1 499 ? 38.80122  -8.63556  -7.30959  1.000 70.39967  ? 499 ALA A CA  1 
ATOM   3791 C  C   . ALA A 1 499 ? 39.06085  -9.84862  -8.19427  1.000 72.77053  ? 499 ALA A C   1 
ATOM   3792 O  O   . ALA A 1 499 ? 38.13478  -10.60470 -8.50100  1.000 76.33908  ? 499 ALA A O   1 
ATOM   3793 C  CB  . ALA A 1 499 ? 38.72156  -7.36826  -8.16508  1.000 59.83096  ? 499 ALA A CB  1 
ATOM   3794 N  N   . LYS A 1 500 ? 40.31449  -10.04518 -8.61205  1.000 60.88007  ? 500 LYS A N   1 
ATOM   3795 C  CA  . LYS A 1 500 ? 40.65081  -11.23014 -9.39475  1.000 63.61843  ? 500 LYS A CA  1 
ATOM   3796 C  C   . LYS A 1 500 ? 40.30957  -12.50322 -8.63659  1.000 72.60588  ? 500 LYS A C   1 
ATOM   3797 O  O   . LYS A 1 500 ? 39.87563  -13.48786 -9.23887  1.000 73.23592  ? 500 LYS A O   1 
ATOM   3798 C  CB  . LYS A 1 500 ? 42.13431  -11.22222 -9.77365  1.000 62.71503  ? 500 LYS A CB  1 
ATOM   3799 C  CG  . LYS A 1 500 ? 42.54535  -12.41833 -10.62953 1.000 61.91686  ? 500 LYS A CG  1 
ATOM   3800 C  CD  . LYS A 1 500 ? 44.05391  -12.52367 -10.79995 1.000 58.42022  ? 500 LYS A CD  1 
ATOM   3801 C  CE  . LYS A 1 500 ? 44.60195  -11.42509 -11.69262 1.000 67.74234  ? 500 LYS A CE  1 
ATOM   3802 N  NZ  . LYS A 1 500 ? 46.01551  -11.70002 -12.07616 1.000 62.51522  ? 500 LYS A NZ  1 
ATOM   3803 N  N   . ALA A 1 501 ? 40.50339  -12.50480 -7.31666  1.000 65.10997  ? 501 ALA A N   1 
ATOM   3804 C  CA  . ALA A 1 501 ? 40.18430  -13.68867 -6.52432  1.000 65.74927  ? 501 ALA A CA  1 
ATOM   3805 C  C   . ALA A 1 501 ? 38.71486  -14.07405 -6.66889  1.000 69.65318  ? 501 ALA A C   1 
ATOM   3806 O  O   . ALA A 1 501 ? 38.38895  -15.24882 -6.88059  1.000 75.69920  ? 501 ALA A O   1 
ATOM   3807 C  CB  . ALA A 1 501 ? 40.54516  -13.44927 -5.05865  1.000 58.55837  ? 501 ALA A CB  1 
ATOM   3808 N  N   . LYS A 1 502 ? 37.81028  -13.09460 -6.56374  1.000 61.69034  ? 502 LYS A N   1 
ATOM   3809 C  CA  . LYS A 1 502 ? 36.38728  -13.38759 -6.72290  1.000 64.87916  ? 502 LYS A CA  1 
ATOM   3810 C  C   . LYS A 1 502 ? 36.07462  -13.88661 -8.12847  1.000 80.53872  ? 502 LYS A C   1 
ATOM   3811 O  O   . LYS A 1 502 ? 35.28827  -14.82625 -8.30112  1.000 94.65380  ? 502 LYS A O   1 
ATOM   3812 C  CB  . LYS A 1 502 ? 35.54850  -12.15109 -6.40147  1.000 71.07661  ? 502 LYS A CB  1 
ATOM   3813 C  CG  . LYS A 1 502 ? 35.04313  -12.09055 -4.96995  1.000 79.86893  ? 502 LYS A CG  1 
ATOM   3814 C  CD  . LYS A 1 502 ? 34.20911  -10.84250 -4.74439  1.000 73.42264  ? 502 LYS A CD  1 
ATOM   3815 C  CE  . LYS A 1 502 ? 33.59918  -10.82979 -3.35748  1.000 73.97691  ? 502 LYS A CE  1 
ATOM   3816 N  NZ  . LYS A 1 502 ? 32.72456  -9.64260  -3.16029  1.000 76.40700  ? 502 LYS A NZ  1 
ATOM   3817 N  N   . TRP A 1 503 ? 36.66559  -13.25941 -9.14788  1.000 76.32343  ? 503 TRP A N   1 
ATOM   3818 C  CA  . TRP A 1 503 ? 36.47183  -13.73100 -10.51533 1.000 70.31004  ? 503 TRP A CA  1 
ATOM   3819 C  C   . TRP A 1 503 ? 37.04199  -15.13162 -10.69793 1.000 73.60964  ? 503 TRP A C   1 
ATOM   3820 O  O   . TRP A 1 503 ? 36.41776  -15.99090 -11.32922 1.000 78.10884  ? 503 TRP A O   1 
ATOM   3821 C  CB  . TRP A 1 503 ? 37.11180  -12.75996 -11.50738 1.000 63.63294  ? 503 TRP A CB  1 
ATOM   3822 C  CG  . TRP A 1 503 ? 37.23613  -13.34192 -12.87979 1.000 72.08981  ? 503 TRP A CG  1 
ATOM   3823 C  CD1 . TRP A 1 503 ? 36.26266  -13.41049 -13.83401 1.000 71.71344  ? 503 TRP A CD1 1 
ATOM   3824 C  CD2 . TRP A 1 503 ? 38.40150  -13.94815 -13.45106 1.000 74.24728  ? 503 TRP A CD2 1 
ATOM   3825 N  NE1 . TRP A 1 503 ? 36.75033  -14.02166 -14.96305 1.000 75.68794  ? 503 TRP A NE1 1 
ATOM   3826 C  CE2 . TRP A 1 503 ? 38.06124  -14.36122 -14.75369 1.000 75.49473  ? 503 TRP A CE2 1 
ATOM   3827 C  CE3 . TRP A 1 503 ? 39.69971  -14.18160 -12.98691 1.000 70.68323  ? 503 TRP A CE3 1 
ATOM   3828 C  CZ2 . TRP A 1 503 ? 38.97228  -14.99265 -15.59759 1.000 76.51254  ? 503 TRP A CZ2 1 
ATOM   3829 C  CZ3 . TRP A 1 503 ? 40.60169  -14.81058 -13.82598 1.000 64.44696  ? 503 TRP A CZ3 1 
ATOM   3830 C  CH2 . TRP A 1 503 ? 40.23424  -15.20797 -15.11589 1.000 75.86523  ? 503 TRP A CH2 1 
ATOM   3831 N  N   . THR A 1 504 ? 38.24110  -15.37080 -10.16382 1.000 64.84013  ? 504 THR A N   1 
ATOM   3832 C  CA  . THR A 1 504 ? 38.86567  -16.68634 -10.25818 1.000 66.93742  ? 504 THR A CA  1 
ATOM   3833 C  C   . THR A 1 504 ? 37.96652  -17.76184 -9.66632  1.000 58.23411  ? 504 THR A C   1 
ATOM   3834 O  O   . THR A 1 504 ? 37.78197  -18.83177 -10.25686 1.000 70.05075  ? 504 THR A O   1 
ATOM   3835 C  CB  . THR A 1 504 ? 40.22034  -16.67637 -9.54467  1.000 60.21674  ? 504 THR A CB  1 
ATOM   3836 O  OG1 . THR A 1 504 ? 41.09523  -15.73599 -10.18120 1.000 59.29411  ? 504 THR A OG1 1 
ATOM   3837 C  CG2 . THR A 1 504 ? 40.85909  -18.05673 -9.58388  1.000 48.12015  ? 504 THR A CG2 1 
ATOM   3838 N  N   . THR A 1 505 ? 37.39618  -17.48650 -8.49171  1.000 65.83214  ? 505 THR A N   1 
ATOM   3839 C  CA  . THR A 1 505 ? 36.51755  -18.45052 -7.83679  1.000 66.82779  ? 505 THR A CA  1 
ATOM   3840 C  C   . THR A 1 505 ? 35.31989  -18.78907 -8.71639  1.000 77.18943  ? 505 THR A C   1 
ATOM   3841 O  O   . THR A 1 505 ? 34.97516  -19.96390 -8.89307  1.000 88.88079  ? 505 THR A O   1 
ATOM   3842 C  CB  . THR A 1 505 ? 36.05903  -17.89362 -6.48873  1.000 58.80985  ? 505 THR A CB  1 
ATOM   3843 O  OG1 . THR A 1 505 ? 37.20618  -17.59689 -5.68175  1.000 61.99874  ? 505 THR A OG1 1 
ATOM   3844 C  CG2 . THR A 1 505 ? 35.17455  -18.89576 -5.76246  1.000 78.04922  ? 505 THR A CG2 1 
ATOM   3845 N  N   . GLN A 1 506 ? 34.68275  -17.76841 -9.29310  1.000 70.51539  ? 506 GLN A N   1 
ATOM   3846 C  CA  . GLN A 1 506 ? 33.52717  -18.00796 -10.14989 1.000 78.30618  ? 506 GLN A CA  1 
ATOM   3847 C  C   . GLN A 1 506 ? 33.93269  -18.59282 -11.49768 1.000 82.53795  ? 506 GLN A C   1 
ATOM   3848 O  O   . GLN A 1 506 ? 33.13436  -19.29098 -12.13334 1.000 75.73489  ? 506 GLN A O   1 
ATOM   3849 C  CB  . GLN A 1 506 ? 32.74402  -16.70936 -10.33945 1.000 65.78964  ? 506 GLN A CB  1 
ATOM   3850 C  CG  . GLN A 1 506 ? 32.06817  -16.20901 -9.07132  1.000 65.47339  ? 506 GLN A CG  1 
ATOM   3851 C  CD  . GLN A 1 506 ? 30.68683  -16.80728 -8.86871  1.000 79.50845  ? 506 GLN A CD  1 
ATOM   3852 O  OE1 . GLN A 1 506 ? 29.76276  -16.54031 -9.63802  1.000 86.36416  ? 506 GLN A OE1 1 
ATOM   3853 N  NE2 . GLN A 1 506 ? 30.54171  -17.62551 -7.83352  1.000 76.18912  ? 506 GLN A NE2 1 
ATOM   3854 N  N   . TRP A 1 507 ? 35.15662  -18.31534 -11.95200 1.000 71.45450  ? 507 TRP A N   1 
ATOM   3855 C  CA  . TRP A 1 507 ? 35.62416  -18.86494 -13.22066 1.000 66.81115  ? 507 TRP A CA  1 
ATOM   3856 C  C   . TRP A 1 507 ? 35.81940  -20.36978 -13.12435 1.000 76.64359  ? 507 TRP A C   1 
ATOM   3857 O  O   . TRP A 1 507 ? 35.38153  -21.11903 -14.00418 1.000 91.72417  ? 507 TRP A O   1 
ATOM   3858 C  CB  . TRP A 1 507 ? 36.92114  -18.17352 -13.64475 1.000 74.27713  ? 507 TRP A CB  1 
ATOM   3859 C  CG  . TRP A 1 507 ? 37.54077  -18.72171 -14.89720 1.000 79.10997  ? 507 TRP A CG  1 
ATOM   3860 C  CD1 . TRP A 1 507 ? 38.38194  -19.79050 -14.99239 1.000 79.70555  ? 507 TRP A CD1 1 
ATOM   3861 C  CD2 . TRP A 1 507 ? 37.38952  -18.21099 -16.22866 1.000 78.50722  ? 507 TRP A CD2 1 
ATOM   3862 N  NE1 . TRP A 1 507 ? 38.75448  -19.98571 -16.29925 1.000 73.73282  ? 507 TRP A NE1 1 
ATOM   3863 C  CE2 . TRP A 1 507 ? 38.16050  -19.02861 -17.07858 1.000 75.32657  ? 507 TRP A CE2 1 
ATOM   3864 C  CE3 . TRP A 1 507 ? 36.67277  -17.14743 -16.78475 1.000 63.62839  ? 507 TRP A CE3 1 
ATOM   3865 C  CZ2 . TRP A 1 507 ? 38.23595  -18.81564 -18.45316 1.000 68.46011  ? 507 TRP A CZ2 1 
ATOM   3866 C  CZ3 . TRP A 1 507 ? 36.75102  -16.93677 -18.14932 1.000 67.77611  ? 507 TRP A CZ3 1 
ATOM   3867 C  CH2 . TRP A 1 507 ? 37.52570  -17.76671 -18.96815 1.000 65.12761  ? 507 TRP A CH2 1 
ATOM   3868 N  N   . ASP A 1 508 ? 36.47446  -20.82965 -12.05586 1.000 74.59290  ? 508 ASP A N   1 
ATOM   3869 C  CA  . ASP A 1 508 ? 36.68862  -22.25958 -11.87796 1.000 77.49156  ? 508 ASP A CA  1 
ATOM   3870 C  C   . ASP A 1 508 ? 35.37129  -23.00006 -11.69210 1.000 79.16685  ? 508 ASP A C   1 
ATOM   3871 O  O   . ASP A 1 508 ? 35.23624  -24.14557 -12.13746 1.000 83.76909  ? 508 ASP A O   1 
ATOM   3872 C  CB  . ASP A 1 508 ? 37.62374  -22.49940 -10.69441 1.000 71.97402  ? 508 ASP A CB  1 
ATOM   3873 C  CG  . ASP A 1 508 ? 38.97434  -21.83268 -10.87646 1.000 79.38164  ? 508 ASP A CG  1 
ATOM   3874 O  OD1 . ASP A 1 508 ? 39.49759  -21.84901 -12.01257 1.000 82.63958  ? 508 ASP A OD1 1 
ATOM   3875 O  OD2 . ASP A 1 508 ? 39.50703  -21.28599 -9.88851  1.000 81.89039  ? 508 ASP A OD2 1 
ATOM   3876 N  N   . LYS A 1 509 ? 34.39338  -22.36752 -11.03803 1.000 70.05509  ? 509 LYS A N   1 
ATOM   3877 C  CA  . LYS A 1 509 ? 33.06489  -22.96168 -10.94763 1.000 79.82471  ? 509 LYS A CA  1 
ATOM   3878 C  C   . LYS A 1 509 ? 32.41170  -23.06488 -12.31943 1.000 76.28150  ? 509 LYS A C   1 
ATOM   3879 O  O   . LYS A 1 509 ? 31.68154  -24.02551 -12.59114 1.000 76.01000  ? 509 LYS A O   1 
ATOM   3880 C  CB  . LYS A 1 509 ? 32.18548  -22.14609 -9.99433  1.000 84.52171  ? 509 LYS A CB  1 
ATOM   3881 C  CG  . LYS A 1 509 ? 30.88259  -22.83721 -9.61698  1.000 78.87069  ? 509 LYS A CG  1 
ATOM   3882 C  CD  . LYS A 1 509 ? 30.08631  -22.04817 -8.58451  1.000 95.24202  ? 509 LYS A CD  1 
ATOM   3883 C  CE  . LYS A 1 509 ? 29.21840  -20.98274 -9.23562  1.000 99.04739  ? 509 LYS A CE  1 
ATOM   3884 N  NZ  . LYS A 1 509 ? 28.29126  -20.34736 -8.25630  1.000 85.67705  ? 509 LYS A NZ  1 
ATOM   3885 N  N   . PHE A 1 510 ? 32.66650  -22.08983 -13.19425 1.000 78.58757  ? 510 PHE A N   1 
ATOM   3886 C  CA  . PHE A 1 510 ? 32.11360  -22.12566 -14.54458 1.000 74.84075  ? 510 PHE A CA  1 
ATOM   3887 C  C   . PHE A 1 510 ? 32.77021  -23.21594 -15.38874 1.000 70.71783  ? 510 PHE A C   1 
ATOM   3888 O  O   . PHE A 1 510 ? 32.08855  -23.90813 -16.15393 1.000 73.25593  ? 510 PHE A O   1 
ATOM   3889 C  CB  . PHE A 1 510 ? 32.26175  -20.74111 -15.18431 1.000 70.45578  ? 510 PHE A CB  1 
ATOM   3890 C  CG  . PHE A 1 510 ? 32.63517  -20.76190 -16.64264 1.000 67.47237  ? 510 PHE A CG  1 
ATOM   3891 C  CD1 . PHE A 1 510 ? 31.68239  -21.00847 -17.61936 1.000 64.42809  ? 510 PHE A CD1 1 
ATOM   3892 C  CD2 . PHE A 1 510 ? 33.93585  -20.48799 -17.03728 1.000 68.07645  ? 510 PHE A CD2 1 
ATOM   3893 C  CE1 . PHE A 1 510 ? 32.02990  -21.01288 -18.95816 1.000 60.99855  ? 510 PHE A CE1 1 
ATOM   3894 C  CE2 . PHE A 1 510 ? 34.28735  -20.48998 -18.37181 1.000 60.92860  ? 510 PHE A CE2 1 
ATOM   3895 C  CZ  . PHE A 1 510 ? 33.33404  -20.75252 -19.33335 1.000 63.86522  ? 510 PHE A CZ  1 
ATOM   3896 N  N   . VAL A 1 511 ? 34.09002  -23.38244 -15.26963 1.000 70.84811  ? 511 VAL A N   1 
ATOM   3897 C  CA  . VAL A 1 511 ? 34.77272  -24.46144 -15.98279 1.000 73.40770  ? 511 VAL A CA  1 
ATOM   3898 C  C   . VAL A 1 511 ? 34.28269  -25.81813 -15.48610 1.000 79.20408  ? 511 VAL A C   1 
ATOM   3899 O  O   . VAL A 1 511 ? 34.02205  -26.73351 -16.27588 1.000 74.88413  ? 511 VAL A O   1 
ATOM   3900 C  CB  . VAL A 1 511 ? 36.30044  -24.32923 -15.83455 1.000 71.77599  ? 511 VAL A CB  1 
ATOM   3901 C  CG1 . VAL A 1 511 ? 37.01502  -25.39636 -16.65830 1.000 59.15975  ? 511 VAL A CG1 1 
ATOM   3902 C  CG2 . VAL A 1 511 ? 36.76746  -22.93785 -16.23828 1.000 78.29730  ? 511 VAL A CG2 1 
ATOM   3903 N  N   . LYS A 1 512 ? 34.15420  -25.96431 -14.16330 1.000 80.02970  ? 512 LYS A N   1 
ATOM   3904 C  CA  . LYS A 1 512 ? 33.78715  -27.24833 -13.56792 1.000 70.08886  ? 512 LYS A CA  1 
ATOM   3905 C  C   . LYS A 1 512 ? 32.41450  -27.71134 -14.04094 1.000 73.71351  ? 512 LYS A C   1 
ATOM   3906 O  O   . LYS A 1 512 ? 32.26049  -28.83765 -14.52620 1.000 83.07428  ? 512 LYS A O   1 
ATOM   3907 C  CB  . LYS A 1 512 ? 33.81884  -27.13234 -12.04110 1.000 72.57470  ? 512 LYS A CB  1 
ATOM   3908 C  CG  . LYS A 1 512 ? 33.35277  -28.37332 -11.28276 1.000 90.54257  ? 512 LYS A CG  1 
ATOM   3909 C  CD  . LYS A 1 512 ? 34.48341  -29.37910 -11.08895 1.000 103.45887 ? 512 LYS A CD  1 
ATOM   3910 C  CE  . LYS A 1 512 ? 34.02368  -30.61390 -10.31450 1.000 100.97255 ? 512 LYS A CE  1 
ATOM   3911 N  NZ  . LYS A 1 512 ? 33.86686  -30.37517 -8.84855  1.000 114.45597 ? 512 LYS A NZ  1 
ATOM   3912 N  N   . THR A 1 513 ? 31.40306  -26.84838 -13.91232 1.000 65.91893  ? 513 THR A N   1 
ATOM   3913 C  CA  . THR A 1 513 ? 30.04143  -27.24349 -14.26209 1.000 72.61227  ? 513 THR A CA  1 
ATOM   3914 C  C   . THR A 1 513 ? 29.89230  -27.46562 -15.76345 1.000 79.49814  ? 513 THR A C   1 
ATOM   3915 O  O   . THR A 1 513 ? 29.16900  -28.37361 -16.19198 1.000 79.43597  ? 513 THR A O   1 
ATOM   3916 C  CB  . THR A 1 513 ? 29.04797  -26.19202 -13.76768 1.000 74.76055  ? 513 THR A CB  1 
ATOM   3917 O  OG1 . THR A 1 513 ? 29.34973  -25.85701 -12.40908 1.000 86.02227  ? 513 THR A OG1 1 
ATOM   3918 C  CG2 . THR A 1 513 ? 27.62310  -26.72639 -13.84501 1.000 65.39373  ? 513 THR A CG2 1 
ATOM   3919 N  N   . SER A 1 514 ? 30.56562  -26.65029 -16.57806 1.000 74.03157  ? 514 SER A N   1 
ATOM   3920 C  CA  . SER A 1 514 ? 30.45944  -26.80398 -18.02652 1.000 75.40678  ? 514 SER A CA  1 
ATOM   3921 C  C   . SER A 1 514 ? 31.09124  -28.11170 -18.49010 1.000 77.20735  ? 514 SER A C   1 
ATOM   3922 O  O   . SER A 1 514 ? 30.47679  -28.87363 -19.24506 1.000 78.94165  ? 514 SER A O   1 
ATOM   3923 C  CB  . SER A 1 514 ? 31.10596  -25.61173 -18.73351 1.000 78.67804  ? 514 SER A CB  1 
ATOM   3924 O  OG  . SER A 1 514 ? 30.43214  -24.40122 -18.43020 1.000 76.97179  ? 514 SER A OG  1 
ATOM   3925 N  N   . VAL A 1 515 ? 32.31799  -28.39225 -18.04194 1.000 75.90601  ? 515 VAL A N   1 
ATOM   3926 C  CA  . VAL A 1 515 ? 32.98244  -29.63780 -18.42192 1.000 76.00941  ? 515 VAL A CA  1 
ATOM   3927 C  C   . VAL A 1 515 ? 32.22113  -30.83921 -17.87260 1.000 72.26269  ? 515 VAL A C   1 
ATOM   3928 O  O   . VAL A 1 515 ? 32.11211  -31.87809 -18.53502 1.000 78.76704  ? 515 VAL A O   1 
ATOM   3929 C  CB  . VAL A 1 515 ? 34.45167  -29.62914 -17.95722 1.000 60.66286  ? 515 VAL A CB  1 
ATOM   3930 C  CG1 . VAL A 1 515 ? 35.10561  -30.98077 -18.20832 1.000 59.55347  ? 515 VAL A CG1 1 
ATOM   3931 C  CG2 . VAL A 1 515 ? 35.22273  -28.53226 -18.67296 1.000 60.21565  ? 515 VAL A CG2 1 
ATOM   3932 N  N   . GLU A 1 516 ? 31.67803  -30.71862 -16.65769 1.000 76.41428  ? 516 GLU A N   1 
ATOM   3933 C  CA  . GLU A 1 516 ? 30.88168  -31.80807 -16.10035 1.000 77.53232  ? 516 GLU A CA  1 
ATOM   3934 C  C   . GLU A 1 516 ? 29.63278  -32.07544 -16.92731 1.000 77.69574  ? 516 GLU A C   1 
ATOM   3935 O  O   . GLU A 1 516 ? 29.20444  -33.22904 -17.04816 1.000 81.46768  ? 516 GLU A O   1 
ATOM   3936 C  CB  . GLU A 1 516 ? 30.49947  -31.50506 -14.65143 1.000 73.84592  ? 516 GLU A CB  1 
ATOM   3937 C  CG  . GLU A 1 516 ? 31.54308  -31.91969 -13.63111 1.000 91.95345  ? 516 GLU A CG  1 
ATOM   3938 C  CD  . GLU A 1 516 ? 30.95672  -32.11080 -12.24483 1.000 98.52347  ? 516 GLU A CD  1 
ATOM   3939 O  OE1 . GLU A 1 516 ? 29.97825  -31.41147 -11.90700 1.000 94.32681  ? 516 GLU A OE1 1 
ATOM   3940 O  OE2 . GLU A 1 516 ? 31.46849  -32.96927 -11.49537 1.000 99.55865  ? 516 GLU A OE2 1 
ATOM   3941 N  N   . GLY A 1 517 ? 29.03123  -31.03264 -17.49427 1.000 78.24509  ? 517 GLY A N   1 
ATOM   3942 C  CA  . GLY A 1 517 ? 27.83541  -31.19556 -18.30068 1.000 76.70230  ? 517 GLY A CA  1 
ATOM   3943 C  C   . GLY A 1 517 ? 28.06676  -31.54962 -19.75012 1.000 80.63876  ? 517 GLY A C   1 
ATOM   3944 O  O   . GLY A 1 517 ? 27.10347  -31.82918 -20.46892 1.000 79.10090  ? 517 GLY A O   1 
ATOM   3945 N  N   . LEU A 1 518 ? 29.32003  -31.54437 -20.20201 1.000 81.53529  ? 518 LEU A N   1 
ATOM   3946 C  CA  . LEU A 1 518 ? 29.66722  -31.88211 -21.57649 1.000 79.17683  ? 518 LEU A CA  1 
ATOM   3947 C  C   . LEU A 1 518 ? 30.47142  -33.16908 -21.68039 1.000 80.49636  ? 518 LEU A C   1 
ATOM   3948 O  O   . LEU A 1 518 ? 30.15711  -34.03184 -22.50624 1.000 71.31487  ? 518 LEU A O   1 
ATOM   3949 C  CB  . LEU A 1 518 ? 30.45358  -30.72720 -22.21918 1.000 70.51128  ? 518 LEU A CB  1 
ATOM   3950 C  CG  . LEU A 1 518 ? 29.77833  -29.35348 -22.30336 1.000 60.60256  ? 518 LEU A CG  1 
ATOM   3951 C  CD1 . LEU A 1 518 ? 30.78693  -28.28895 -22.71338 1.000 54.94190  ? 518 LEU A CD1 1 
ATOM   3952 C  CD2 . LEU A 1 518 ? 28.59687  -29.37220 -23.26127 1.000 63.62279  ? 518 LEU A CD2 1 
ATOM   3953 N  N   . LYS A 1 519 ? 31.51050  -33.31564 -20.86279 1.000 79.07495  ? 519 LYS A N   1 
ATOM   3954 C  CA  . LYS A 1 519 ? 32.33535  -34.51406 -20.90775 1.000 70.42203  ? 519 LYS A CA  1 
ATOM   3955 C  C   . LYS A 1 519 ? 31.56000  -35.70973 -20.35992 1.000 84.17630  ? 519 LYS A C   1 
ATOM   3956 O  O   . LYS A 1 519 ? 30.78544  -35.56445 -19.40900 1.000 82.56170  ? 519 LYS A O   1 
ATOM   3957 C  CB  . LYS A 1 519 ? 33.61871  -34.31573 -20.10160 1.000 70.51350  ? 519 LYS A CB  1 
ATOM   3958 C  CG  . LYS A 1 519 ? 34.79477  -33.78479 -20.90275 1.000 83.14568  ? 519 LYS A CG  1 
ATOM   3959 C  CD  . LYS A 1 519 ? 35.11900  -34.69818 -22.07541 1.000 83.66934  ? 519 LYS A CD  1 
ATOM   3960 C  CE  . LYS A 1 519 ? 36.54986  -34.51154 -22.55449 1.000 80.51150  ? 519 LYS A CE  1 
ATOM   3961 N  NZ  . LYS A 1 519 ? 37.53204  -35.04895 -21.57303 1.000 82.92424  ? 519 LYS A NZ  1 
ATOM   3962 N  N   . PRO A 1 520 ? 31.74431  -36.89605 -20.93429 1.000 82.84611  ? 520 PRO A N   1 
ATOM   3963 C  CA  . PRO A 1 520 ? 31.06584  -38.08457 -20.41053 1.000 64.78882  ? 520 PRO A CA  1 
ATOM   3964 C  C   . PRO A 1 520 ? 31.63235  -38.50427 -19.06256 1.000 80.73285  ? 520 PRO A C   1 
ATOM   3965 O  O   . PRO A 1 520 ? 32.73955  -38.12714 -18.67163 1.000 88.70552  ? 520 PRO A O   1 
ATOM   3966 C  CB  . PRO A 1 520 ? 31.33209  -39.14541 -21.48278 1.000 67.85648  ? 520 PRO A CB  1 
ATOM   3967 C  CG  . PRO A 1 520 ? 32.59857  -38.70588 -22.12746 1.000 66.31461  ? 520 PRO A CG  1 
ATOM   3968 C  CD  . PRO A 1 520 ? 32.56822  -37.20429 -22.11578 1.000 73.98053  ? 520 PRO A CD  1 
ATOM   3969 N  N   . HIS A 1 521 ? 30.83879  -39.29300 -18.34363 1.000 81.29593  ? 521 HIS A N   1 
ATOM   3970 C  CA  . HIS A 1 521 ? 31.21294  -39.75315 -17.01142 1.000 72.57660  ? 521 HIS A CA  1 
ATOM   3971 C  C   . HIS A 1 521 ? 31.25288  -41.27869 -16.93622 1.000 64.96116  ? 521 HIS A C   1 
ATOM   3972 O  O   . HIS A 1 521 ? 32.14498  -41.85255 -16.30987 1.000 78.74055  ? 521 HIS A O   1 
ATOM   3973 C  CB  . HIS A 1 521 ? 30.24123  -39.19157 -15.96943 1.000 95.66206  ? 521 HIS A CB  1 
ATOM   3974 C  CG  . HIS A 1 521 ? 30.30625  -37.70128 -15.83437 1.000 119.86953 ? 521 HIS A CG  1 
ATOM   3975 N  ND1 . HIS A 1 521 ? 31.46180  -36.98511 -16.06021 1.000 119.72702 ? 521 HIS A ND1 1 
ATOM   3976 C  CD2 . HIS A 1 521 ? 29.35925  -36.79067 -15.50573 1.000 100.78323 ? 521 HIS A CD2 1 
ATOM   3977 C  CE1 . HIS A 1 521 ? 31.22571  -35.69896 -15.87015 1.000 94.37248  ? 521 HIS A CE1 1 
ATOM   3978 N  NE2 . HIS A 1 521 ? 29.95729  -35.55385 -15.53266 1.000 90.01864  ? 521 HIS A NE2 1 
ATOM   3979 N  N   . LYS B 1 31  ? 47.74634  26.58785  -21.99751 1.000 58.88797  ? 31  LYS B N   1 
ATOM   3980 C  CA  . LYS B 1 31  ? 49.12471  27.04394  -21.84018 1.000 86.73506  ? 31  LYS B CA  1 
ATOM   3981 C  C   . LYS B 1 31  ? 49.93967  26.71218  -23.09222 1.000 94.97546  ? 31  LYS B C   1 
ATOM   3982 O  O   . LYS B 1 31  ? 49.74741  25.66356  -23.70870 1.000 84.68094  ? 31  LYS B O   1 
ATOM   3983 C  CB  . LYS B 1 31  ? 49.76110  26.40669  -20.59707 1.000 75.46551  ? 31  LYS B CB  1 
ATOM   3984 C  CG  . LYS B 1 31  ? 50.58839  27.35245  -19.72444 1.000 72.80842  ? 31  LYS B CG  1 
ATOM   3985 C  CD  . LYS B 1 31  ? 51.77369  27.93457  -20.46686 1.000 76.13368  ? 31  LYS B CD  1 
ATOM   3986 C  CE  . LYS B 1 31  ? 52.56264  28.88070  -19.58667 1.000 78.56656  ? 31  LYS B CE  1 
ATOM   3987 N  NZ  . LYS B 1 31  ? 53.61869  29.56763  -20.37536 1.000 59.71287  ? 31  LYS B NZ  1 
ATOM   3988 N  N   . ALA B 1 32  ? 50.84976  27.61974  -23.46215 1.000 102.53010 ? 32  ALA B N   1 
ATOM   3989 C  CA  . ALA B 1 32  ? 51.71383  27.39318  -24.61747 1.000 89.92904  ? 32  ALA B CA  1 
ATOM   3990 C  C   . ALA B 1 32  ? 52.59486  26.16445  -24.43311 1.000 91.98605  ? 32  ALA B C   1 
ATOM   3991 O  O   . ALA B 1 32  ? 52.95807  25.51003  -25.41756 1.000 98.84880  ? 32  ALA B O   1 
ATOM   3992 C  CB  . ALA B 1 32  ? 52.57691  28.62661  -24.87694 1.000 102.86796 ? 32  ALA B CB  1 
ATOM   3993 N  N   . ALA B 1 33  ? 52.95551  25.84251  -23.18810 1.000 91.62462  ? 33  ALA B N   1 
ATOM   3994 C  CA  . ALA B 1 33  ? 53.78009  24.66559  -22.93005 1.000 96.20507  ? 33  ALA B CA  1 
ATOM   3995 C  C   . ALA B 1 33  ? 53.07482  23.38936  -23.37357 1.000 90.22730  ? 33  ALA B C   1 
ATOM   3996 O  O   . ALA B 1 33  ? 53.68370  22.51570  -24.00183 1.000 91.07308  ? 33  ALA B O   1 
ATOM   3997 C  CB  . ALA B 1 33  ? 54.13975  24.59580  -21.44606 1.000 97.30342  ? 33  ALA B CB  1 
ATOM   3998 N  N   . TYR B 1 34  ? 51.78561  23.26200  -23.05125 1.000 84.26251  ? 34  TYR B N   1 
ATOM   3999 C  CA  . TYR B 1 34  ? 51.01466  22.11920  -23.53245 1.000 85.37300  ? 34  TYR B CA  1 
ATOM   4000 C  C   . TYR B 1 34  ? 50.93805  22.11152  -25.05365 1.000 85.94412  ? 34  TYR B C   1 
ATOM   4001 O  O   . TYR B 1 34  ? 51.06133  21.05486  -25.68468 1.000 84.77665  ? 34  TYR B O   1 
ATOM   4002 C  CB  . TYR B 1 34  ? 49.61075  22.13857  -22.92278 1.000 75.38511  ? 34  TYR B CB  1 
ATOM   4003 C  CG  . TYR B 1 34  ? 48.69137  21.04702  -23.43432 1.000 75.53362  ? 34  TYR B CG  1 
ATOM   4004 C  CD1 . TYR B 1 34  ? 48.60889  19.81995  -22.78895 1.000 74.63212  ? 34  TYR B CD1 1 
ATOM   4005 C  CD2 . TYR B 1 34  ? 47.89986  21.24859  -24.55761 1.000 72.81103  ? 34  TYR B CD2 1 
ATOM   4006 C  CE1 . TYR B 1 34  ? 47.76701  18.82385  -23.25368 1.000 64.27016  ? 34  TYR B CE1 1 
ATOM   4007 C  CE2 . TYR B 1 34  ? 47.05985  20.26146  -25.02864 1.000 71.17459  ? 34  TYR B CE2 1 
ATOM   4008 C  CZ  . TYR B 1 34  ? 46.99557  19.05258  -24.37399 1.000 75.03164  ? 34  TYR B CZ  1 
ATOM   4009 O  OH  . TYR B 1 34  ? 46.15578  18.07115  -24.84567 1.000 92.01338  ? 34  TYR B OH  1 
ATOM   4010 N  N   . LEU B 1 35  ? 50.71888  23.28188  -25.65817 1.000 80.61268  ? 35  LEU B N   1 
ATOM   4011 C  CA  . LEU B 1 35  ? 50.60568  23.36205  -27.10986 1.000 76.69654  ? 35  LEU B CA  1 
ATOM   4012 C  C   . LEU B 1 35  ? 51.88943  22.92046  -27.80083 1.000 86.05598  ? 35  LEU B C   1 
ATOM   4013 O  O   . LEU B 1 35  ? 51.83780  22.34465  -28.89328 1.000 99.60410  ? 35  LEU B O   1 
ATOM   4014 C  CB  . LEU B 1 35  ? 50.24249  24.79033  -27.52240 1.000 78.68921  ? 35  LEU B CB  1 
ATOM   4015 C  CG  . LEU B 1 35  ? 48.95005  25.35288  -26.92361 1.000 79.00627  ? 35  LEU B CG  1 
ATOM   4016 C  CD1 . LEU B 1 35  ? 48.83666  26.84650  -27.18895 1.000 86.23473  ? 35  LEU B CD1 1 
ATOM   4017 C  CD2 . LEU B 1 35  ? 47.73380  24.61648  -27.46587 1.000 74.85314  ? 35  LEU B CD2 1 
ATOM   4018 N  N   . LEU B 1 36  ? 53.04553  23.18323  -27.18639 1.000 88.47405  ? 36  LEU B N   1 
ATOM   4019 C  CA  . LEU B 1 36  ? 54.31101  22.75396  -27.77311 1.000 93.70548  ? 36  LEU B CA  1 
ATOM   4020 C  C   . LEU B 1 36  ? 54.45382  21.23713  -27.74056 1.000 79.12784  ? 36  LEU B C   1 
ATOM   4021 O  O   . LEU B 1 36  ? 54.89602  20.62860  -28.72434 1.000 80.92339  ? 36  LEU B O   1 
ATOM   4022 C  CB  . LEU B 1 36  ? 55.47888  23.41957  -27.04701 1.000 94.16006  ? 36  LEU B CB  1 
ATOM   4023 C  CG  . LEU B 1 36  ? 55.58837  24.93712  -27.20178 1.000 92.71504  ? 36  LEU B CG  1 
ATOM   4024 C  CD1 . LEU B 1 36  ? 56.87327  25.44675  -26.56701 1.000 78.63408  ? 36  LEU B CD1 1 
ATOM   4025 C  CD2 . LEU B 1 36  ? 55.50226  25.34490  -28.66904 1.000 92.57268  ? 36  LEU B CD2 1 
ATOM   4026 N  N   . LYS B 1 37  ? 54.08935  20.60971  -26.61800 1.000 82.36208  ? 37  LYS B N   1 
ATOM   4027 C  CA  . LYS B 1 37  ? 54.13929  19.15337  -26.53445 1.000 86.47374  ? 37  LYS B CA  1 
ATOM   4028 C  C   . LYS B 1 37  ? 53.16040  18.50306  -27.50385 1.000 79.85292  ? 37  LYS B C   1 
ATOM   4029 O  O   . LYS B 1 37  ? 53.45081  17.43581  -28.05529 1.000 67.88216  ? 37  LYS B O   1 
ATOM   4030 C  CB  . LYS B 1 37  ? 53.85172  18.70624  -25.09654 1.000 73.19633  ? 37  LYS B CB  1 
ATOM   4031 C  CG  . LYS B 1 37  ? 53.71925  17.19837  -24.90127 1.000 95.96330  ? 37  LYS B CG  1 
ATOM   4032 C  CD  . LYS B 1 37  ? 54.95895  16.43821  -25.35595 1.000 109.52234 ? 37  LYS B CD  1 
ATOM   4033 C  CE  . LYS B 1 37  ? 54.77256  14.93882  -25.17043 1.000 95.11662  ? 37  LYS B CE  1 
ATOM   4034 N  NZ  . LYS B 1 37  ? 55.86591  14.15379  -25.80286 1.000 100.26743 ? 37  LYS B NZ  1 
ATOM   4035 N  N   . ARG B 1 38  ? 52.00480  19.13005  -27.73053 1.000 81.58993  ? 38  ARG B N   1 
ATOM   4036 C  CA  . ARG B 1 38  ? 51.03090  18.57590  -28.66586 1.000 71.03781  ? 38  ARG B CA  1 
ATOM   4037 C  C   . ARG B 1 38  ? 51.54925  18.62072  -30.09742 1.000 71.55271  ? 38  ARG B C   1 
ATOM   4038 O  O   . ARG B 1 38  ? 51.45293  17.63207  -30.83357 1.000 69.19476  ? 38  ARG B O   1 
ATOM   4039 C  CB  . ARG B 1 38  ? 49.70611  19.32796  -28.54855 1.000 68.75400  ? 38  ARG B CB  1 
ATOM   4040 C  CG  . ARG B 1 38  ? 48.61883  18.81308  -29.47440 1.000 68.76657  ? 38  ARG B CG  1 
ATOM   4041 C  CD  . ARG B 1 38  ? 47.34617  19.62792  -29.32780 1.000 66.30351  ? 38  ARG B CD  1 
ATOM   4042 N  NE  . ARG B 1 38  ? 46.25702  19.07707  -30.12348 1.000 60.88702  ? 38  ARG B NE  1 
ATOM   4043 C  CZ  . ARG B 1 38  ? 46.07750  19.31901  -31.41456 1.000 76.58929  ? 38  ARG B CZ  1 
ATOM   4044 N  NH1 . ARG B 1 38  ? 46.89791  20.10634  -32.09097 1.000 81.86910  ? 38  ARG B NH1 1 
ATOM   4045 N  NH2 . ARG B 1 38  ? 45.05082  18.75435  -32.04388 1.000 81.23237  ? 38  ARG B NH2 1 
ATOM   4046 N  N   . ASN B 1 39  ? 52.10095  19.76399  -30.51165 1.000 64.30127  ? 39  ASN B N   1 
ATOM   4047 C  CA  . ASN B 1 39  ? 52.59074  19.89166  -31.87999 1.000 75.00167  ? 39  ASN B CA  1 
ATOM   4048 C  C   . ASN B 1 39  ? 53.81905  19.02371  -32.12213 1.000 85.19589  ? 39  ASN B C   1 
ATOM   4049 O  O   . ASN B 1 39  ? 54.00314  18.51042  -33.23089 1.000 90.54531  ? 39  ASN B O   1 
ATOM   4050 C  CB  . ASN B 1 39  ? 52.89250  21.35685  -32.19401 1.000 64.78075  ? 39  ASN B CB  1 
ATOM   4051 C  CG  . ASN B 1 39  ? 51.63443  22.19960  -32.29595 1.000 76.38381  ? 39  ASN B CG  1 
ATOM   4052 O  OD1 . ASN B 1 39  ? 50.51980  21.69089  -32.16852 1.000 75.71263  ? 39  ASN B OD1 1 
ATOM   4053 N  ND2 . ASN B 1 39  ? 51.80745  23.49663  -32.52021 1.000 86.91931  ? 39  ASN B ND2 1 
ATOM   4054 N  N   . SER B 1 40  ? 54.66583  18.84614  -31.10578 1.000 70.57750  ? 40  SER B N   1 
ATOM   4055 C  CA  . SER B 1 40  ? 55.79975  17.93906  -31.24449 1.000 67.61479  ? 40  SER B CA  1 
ATOM   4056 C  C   . SER B 1 40  ? 55.33256  16.50465  -31.45555 1.000 84.86801  ? 40  SER B C   1 
ATOM   4057 O  O   . SER B 1 40  ? 55.90597  15.76876  -32.26776 1.000 93.65829  ? 40  SER B O   1 
ATOM   4058 C  CB  . SER B 1 40  ? 56.70399  18.03662  -30.01570 1.000 69.88455  ? 40  SER B CB  1 
ATOM   4059 O  OG  . SER B 1 40  ? 57.60708  16.94576  -29.95303 1.000 86.07483  ? 40  SER B OG  1 
ATOM   4060 N  N   . LEU B 1 41  ? 54.29199  16.08919  -30.72931 1.000 83.84053  ? 41  LEU B N   1 
ATOM   4061 C  CA  . LEU B 1 41  ? 53.78644  14.72644  -30.86227 1.000 70.77069  ? 41  LEU B CA  1 
ATOM   4062 C  C   . LEU B 1 41  ? 53.20635  14.48046  -32.25060 1.000 77.00521  ? 41  LEU B C   1 
ATOM   4063 O  O   . LEU B 1 41  ? 53.44833  13.42846  -32.85367 1.000 92.44964  ? 41  LEU B O   1 
ATOM   4064 C  CB  . LEU B 1 41  ? 52.73562  14.45969  -29.78444 1.000 76.48792  ? 41  LEU B CB  1 
ATOM   4065 C  CG  . LEU B 1 41  ? 52.47291  13.00454  -29.39853 1.000 73.48884  ? 41  LEU B CG  1 
ATOM   4066 C  CD1 . LEU B 1 41  ? 53.74602  12.35006  -28.88073 1.000 87.80830  ? 41  LEU B CD1 1 
ATOM   4067 C  CD2 . LEU B 1 41  ? 51.36712  12.93050  -28.35838 1.000 59.82669  ? 41  LEU B CD2 1 
ATOM   4068 N  N   . ILE B 1 42  ? 52.43496  15.43792  -32.77282 1.000 82.00736  ? 42  ILE B N   1 
ATOM   4069 C  CA  . ILE B 1 42  ? 51.83439  15.27594  -34.09631 1.000 74.46572  ? 42  ILE B CA  1 
ATOM   4070 C  C   . ILE B 1 42  ? 52.91364  15.23400  -35.17088 1.000 76.00157  ? 42  ILE B C   1 
ATOM   4071 O  O   . ILE B 1 42  ? 52.88451  14.38894  -36.07305 1.000 87.26129  ? 42  ILE B O   1 
ATOM   4072 C  CB  . ILE B 1 42  ? 50.81311  16.39522  -34.36519 1.000 67.73857  ? 42  ILE B CB  1 
ATOM   4073 C  CG1 . ILE B 1 42  ? 49.60022  16.23635  -33.44586 1.000 73.88950  ? 42  ILE B CG1 1 
ATOM   4074 C  CG2 . ILE B 1 42  ? 50.38639  16.39589  -35.82670 1.000 62.37175  ? 42  ILE B CG2 1 
ATOM   4075 C  CD1 . ILE B 1 42  ? 48.48024  17.20818  -33.73642 1.000 70.04967  ? 42  ILE B CD1 1 
ATOM   4076 N  N   . GLU B 1 43  ? 53.88358  16.14807  -35.09254 1.000 84.81099  ? 43  GLU B N   1 
ATOM   4077 C  CA  . GLU B 1 43  ? 54.98701  16.13479  -36.04618 1.000 91.62816  ? 43  GLU B CA  1 
ATOM   4078 C  C   . GLU B 1 43  ? 55.84173  14.88411  -35.90679 1.000 84.87725  ? 43  GLU B C   1 
ATOM   4079 O  O   . GLU B 1 43  ? 56.54842  14.51898  -36.85128 1.000 88.71675  ? 43  GLU B O   1 
ATOM   4080 C  CB  . GLU B 1 43  ? 55.85747  17.37988  -35.87222 1.000 96.65109  ? 43  GLU B CB  1 
ATOM   4081 C  CG  . GLU B 1 43  ? 55.14983  18.68751  -36.18412 1.000 99.36608  ? 43  GLU B CG  1 
ATOM   4082 C  CD  . GLU B 1 43  ? 55.92681  19.89734  -35.69795 1.000 122.17947 ? 43  GLU B CD  1 
ATOM   4083 O  OE1 . GLU B 1 43  ? 57.03452  19.71312  -35.14925 1.000 128.85969 ? 43  GLU B OE1 1 
ATOM   4084 O  OE2 . GLU B 1 43  ? 55.43025  21.03198  -35.86076 1.000 128.99115 ? 43  GLU B OE2 1 
ATOM   4085 N  N   . GLU B 1 44  ? 55.80132  14.22962  -34.74677 1.000 82.08879  ? 44  GLU B N   1 
ATOM   4086 C  CA  . GLU B 1 44  ? 56.51701  12.97493  -34.55969 1.000 91.58387  ? 44  GLU B CA  1 
ATOM   4087 C  C   . GLU B 1 44  ? 55.76713  11.79781  -35.17286 1.000 88.46387  ? 44  GLU B C   1 
ATOM   4088 O  O   . GLU B 1 44  ? 56.39540  10.83395  -35.62479 1.000 84.67985  ? 44  GLU B O   1 
ATOM   4089 C  CB  . GLU B 1 44  ? 56.75618  12.74566  -33.06648 1.000 96.57550  ? 44  GLU B CB  1 
ATOM   4090 C  CG  . GLU B 1 44  ? 57.64406  11.56704  -32.72975 1.000 99.49920  ? 44  GLU B CG  1 
ATOM   4091 C  CD  . GLU B 1 44  ? 57.92929  11.47736  -31.24442 1.000 116.14564 ? 44  GLU B CD  1 
ATOM   4092 O  OE1 . GLU B 1 44  ? 57.62524  12.45292  -30.52405 1.000 109.44230 ? 44  GLU B OE1 1 
ATOM   4093 O  OE2 . GLU B 1 44  ? 58.46444  10.43943  -30.79971 1.000 102.21142 ? 44  GLU B OE2 1 
ATOM   4094 N  N   . ASP B 1 45  ? 54.43420  11.86068  -35.19929 1.000 80.57869  ? 45  ASP B N   1 
ATOM   4095 C  CA  . ASP B 1 45  ? 53.63779  10.79485  -35.79822 1.000 77.78954  ? 45  ASP B CA  1 
ATOM   4096 C  C   . ASP B 1 45  ? 53.55350  10.94577  -37.31369 1.000 75.14242  ? 45  ASP B C   1 
ATOM   4097 O  O   . ASP B 1 45  ? 53.84987  10.00241  -38.05651 1.000 85.41929  ? 45  ASP B O   1 
ATOM   4098 C  CB  . ASP B 1 45  ? 52.23718  10.78313  -35.18049 1.000 84.49191  ? 45  ASP B CB  1 
ATOM   4099 C  CG  . ASP B 1 45  ? 51.38408  9.64140   -35.69374 1.000 84.96822  ? 45  ASP B CG  1 
ATOM   4100 O  OD1 . ASP B 1 45  ? 51.42053  8.55079   -35.08885 1.000 70.28341  ? 45  ASP B OD1 1 
ATOM   4101 O  OD2 . ASP B 1 45  ? 50.68463  9.83063   -36.71061 1.000 89.99062  ? 45  ASP B OD2 1 
ATOM   4102 N  N   . ALA B 1 46  ? 53.15556  12.13066  -37.78665 1.000 68.15676  ? 46  ALA B N   1 
ATOM   4103 C  CA  . ALA B 1 46  ? 52.99799  12.39112  -39.21197 1.000 71.50167  ? 46  ALA B CA  1 
ATOM   4104 C  C   . ALA B 1 46  ? 54.31584  12.36167  -39.97848 1.000 72.06706  ? 46  ALA B C   1 
ATOM   4105 O  O   . ALA B 1 46  ? 54.28865  12.27708  -41.21152 1.000 79.36687  ? 46  ALA B O   1 
ATOM   4106 C  CB  . ALA B 1 46  ? 52.31307  13.74265  -39.42324 1.000 61.78341  ? 46  ALA B CB  1 
ATOM   4107 N  N   . SER B 1 47  ? 55.46086  12.42777  -39.29199 1.000 72.60663  ? 47  SER B N   1 
ATOM   4108 C  CA  . SER B 1 47  ? 56.75111  12.34173  -39.96770 1.000 78.06799  ? 47  SER B CA  1 
ATOM   4109 C  C   . SER B 1 47  ? 57.02829  10.95419  -40.52436 1.000 80.26992  ? 47  SER B C   1 
ATOM   4110 O  O   . SER B 1 47  ? 58.00106  10.78709  -41.26740 1.000 88.84947  ? 47  SER B O   1 
ATOM   4111 C  CB  . SER B 1 47  ? 57.88096  12.74017  -39.01422 1.000 77.92057  ? 47  SER B CB  1 
ATOM   4112 O  OG  . SER B 1 47  ? 57.98216  11.83543  -37.92703 1.000 80.10378  ? 47  SER B OG  1 
ATOM   4113 N  N   . ARG B 1 48  ? 56.21220  9.96238   -40.17698 1.000 77.39333  ? 48  ARG B N   1 
ATOM   4114 C  CA  . ARG B 1 48  ? 56.41364  8.58844   -40.60831 1.000 82.07025  ? 48  ARG B CA  1 
ATOM   4115 C  C   . ARG B 1 48  ? 55.48615  8.18373   -41.74776 1.000 88.70517  ? 48  ARG B C   1 
ATOM   4116 O  O   . ARG B 1 48  ? 55.47470  7.01174   -42.13453 1.000 93.01950  ? 48  ARG B O   1 
ATOM   4117 C  CB  . ARG B 1 48  ? 56.23827  7.64799   -39.41601 1.000 67.40195  ? 48  ARG B CB  1 
ATOM   4118 C  CG  . ARG B 1 48  ? 57.07392  8.07074   -38.22270 1.000 77.76937  ? 48  ARG B CG  1 
ATOM   4119 C  CD  . ARG B 1 48  ? 56.66042  7.36747   -36.94311 1.000 80.63948  ? 48  ARG B CD  1 
ATOM   4120 N  NE  . ARG B 1 48  ? 56.77747  5.91826   -37.03669 1.000 70.84973  ? 48  ARG B NE  1 
ATOM   4121 C  CZ  . ARG B 1 48  ? 57.02187  5.12478   -36.00315 1.000 84.16504  ? 48  ARG B CZ  1 
ATOM   4122 N  NH1 . ARG B 1 48  ? 57.19654  5.61145   -34.78509 1.000 80.27399  ? 48  ARG B NH1 1 
ATOM   4123 N  NH2 . ARG B 1 48  ? 57.10646  3.81180   -36.19807 1.000 96.56319  ? 48  ARG B NH2 1 
ATOM   4124 N  N   . LYS B 1 49  ? 54.72305  9.12277   -42.30252 1.000 90.30919  ? 49  LYS B N   1 
ATOM   4125 C  CA  . LYS B 1 49  ? 53.84762  8.80650   -43.41840 1.000 73.76226  ? 49  LYS B CA  1 
ATOM   4126 C  C   . LYS B 1 49  ? 54.67059  8.53917   -44.67690 1.000 77.67076  ? 49  LYS B C   1 
ATOM   4127 O  O   . LYS B 1 49  ? 55.87040  8.82034   -44.74380 1.000 80.41310  ? 49  LYS B O   1 
ATOM   4128 C  CB  . LYS B 1 49  ? 52.85753  9.94336   -43.67114 1.000 70.25136  ? 49  LYS B CB  1 
ATOM   4129 C  CG  . LYS B 1 49  ? 51.48073  9.74112   -43.05466 1.000 90.43183  ? 49  LYS B CG  1 
ATOM   4130 C  CD  . LYS B 1 49  ? 51.49862  9.91364   -41.54713 1.000 99.63691  ? 49  LYS B CD  1 
ATOM   4131 C  CE  . LYS B 1 49  ? 50.11137  9.70782   -40.96496 1.000 98.71093  ? 49  LYS B CE  1 
ATOM   4132 N  NZ  . LYS B 1 49  ? 50.02446  10.19439  -39.56357 1.000 85.11211  ? 49  LYS B NZ  1 
ATOM   4133 N  N   . LEU B 1 50  ? 54.00611  7.98430   -45.68707 1.000 85.94224  ? 50  LEU B N   1 
ATOM   4134 C  CA  . LEU B 1 50  ? 54.65809  7.67821   -46.95327 1.000 82.58234  ? 50  LEU B CA  1 
ATOM   4135 C  C   . LEU B 1 50  ? 54.87933  8.97414   -47.72328 1.000 81.89837  ? 50  LEU B C   1 
ATOM   4136 O  O   . LEU B 1 50  ? 53.92112  9.69505   -48.02401 1.000 78.59008  ? 50  LEU B O   1 
ATOM   4137 C  CB  . LEU B 1 50  ? 53.80917  6.70269   -47.76406 1.000 84.48019  ? 50  LEU B CB  1 
ATOM   4138 C  CG  . LEU B 1 50  ? 54.48720  6.00005   -48.94067 1.000 79.80517  ? 50  LEU B CG  1 
ATOM   4139 C  CD1 . LEU B 1 50  ? 55.28183  4.80283   -48.45043 1.000 75.32089  ? 50  LEU B CD1 1 
ATOM   4140 C  CD2 . LEU B 1 50  ? 53.46539  5.57807   -49.97850 1.000 64.95297  ? 50  LEU B CD2 1 
ATOM   4141 N  N   . GLY B 1 51  ? 56.13598  9.26839   -48.04406 1.000 80.44198  ? 51  GLY B N   1 
ATOM   4142 C  CA  . GLY B 1 51  ? 56.48090  10.51293  -48.69646 1.000 79.87001  ? 51  GLY B CA  1 
ATOM   4143 C  C   . GLY B 1 51  ? 56.71495  11.68149  -47.76794 1.000 78.81459  ? 51  GLY B C   1 
ATOM   4144 O  O   . GLY B 1 51  ? 56.83048  12.81601  -48.24692 1.000 85.43209  ? 51  GLY B O   1 
ATOM   4145 N  N   . ALA B 1 52  ? 56.79178  11.44395  -46.45543 1.000 76.79966  ? 52  ALA B N   1 
ATOM   4146 C  CA  . ALA B 1 52  ? 57.01205  12.52540  -45.50261 1.000 79.08335  ? 52  ALA B CA  1 
ATOM   4147 C  C   . ALA B 1 52  ? 58.37401  13.18671  -45.67023 1.000 83.21953  ? 52  ALA B C   1 
ATOM   4148 O  O   . ALA B 1 52  ? 58.57768  14.29236  -45.15818 1.000 92.54395  ? 52  ALA B O   1 
ATOM   4149 C  CB  . ALA B 1 52  ? 56.86221  12.00530  -44.07237 1.000 85.16394  ? 52  ALA B CB  1 
ATOM   4150 N  N   . LYS B 1 53  ? 59.30928  12.53893  -46.36121 1.000 83.12331  ? 53  LYS B N   1 
ATOM   4151 C  CA  . LYS B 1 53  ? 60.62825  13.10404  -46.60621 1.000 91.99909  ? 53  LYS B CA  1 
ATOM   4152 C  C   . LYS B 1 53  ? 60.79372  13.62355  -48.02662 1.000 87.06757  ? 53  LYS B C   1 
ATOM   4153 O  O   . LYS B 1 53  ? 61.89194  14.06161  -48.38856 1.000 88.34839  ? 53  LYS B O   1 
ATOM   4154 C  CB  . LYS B 1 53  ? 61.70648  12.06372  -46.28768 1.000 76.81998  ? 53  LYS B CB  1 
ATOM   4155 C  CG  . LYS B 1 53  ? 61.56958  11.50128  -44.88338 1.000 81.01704  ? 53  LYS B CG  1 
ATOM   4156 C  CD  . LYS B 1 53  ? 62.77150  10.68213  -44.46082 1.000 94.75372  ? 53  LYS B CD  1 
ATOM   4157 C  CE  . LYS B 1 53  ? 62.63594  10.25830  -43.00513 1.000 88.69667  ? 53  LYS B CE  1 
ATOM   4158 N  NZ  . LYS B 1 53  ? 63.81828  9.49813   -42.51412 1.000 94.63293  ? 53  LYS B NZ  1 
ATOM   4159 N  N   . ILE B 1 54  ? 59.73517  13.58265  -48.83556 1.000 78.45921  ? 54  ILE B N   1 
ATOM   4160 C  CA  . ILE B 1 54  ? 59.76029  14.22479  -50.14304 1.000 77.37055  ? 54  ILE B CA  1 
ATOM   4161 C  C   . ILE B 1 54  ? 59.84492  15.73311  -49.95639 1.000 90.18798  ? 54  ILE B C   1 
ATOM   4162 O  O   . ILE B 1 54  ? 59.03707  16.33389  -49.23373 1.000 97.97026  ? 54  ILE B O   1 
ATOM   4163 C  CB  . ILE B 1 54  ? 58.51679  13.83876  -50.95807 1.000 76.89718  ? 54  ILE B CB  1 
ATOM   4164 C  CG1 . ILE B 1 54  ? 58.64999  12.42035  -51.51781 1.000 71.79149  ? 54  ILE B CG1 1 
ATOM   4165 C  CG2 . ILE B 1 54  ? 58.27992  14.83598  -52.08607 1.000 79.83664  ? 54  ILE B CG2 1 
ATOM   4166 C  CD1 . ILE B 1 54  ? 59.59901  12.31325  -52.69061 1.000 74.15231  ? 54  ILE B CD1 1 
ATOM   4167 N  N   . VAL B 1 55  ? 60.82574  16.35278  -50.60385 1.000 90.84197  ? 55  VAL B N   1 
ATOM   4168 C  CA  . VAL B 1 55  ? 60.97818  17.80177  -50.59848 1.000 81.98855  ? 55  VAL B CA  1 
ATOM   4169 C  C   . VAL B 1 55  ? 60.37717  18.33436  -51.88846 1.000 81.73725  ? 55  VAL B C   1 
ATOM   4170 O  O   . VAL B 1 55  ? 60.83236  17.99272  -52.98644 1.000 79.21998  ? 55  VAL B O   1 
ATOM   4171 C  CB  . VAL B 1 55  ? 62.44965  18.21740  -50.45890 1.000 83.85454  ? 55  VAL B CB  1 
ATOM   4172 C  CG1 . VAL B 1 55  ? 62.57780  19.73285  -50.52829 1.000 95.27273  ? 55  VAL B CG1 1 
ATOM   4173 C  CG2 . VAL B 1 55  ? 63.02645  17.68849  -49.15659 1.000 86.25062  ? 55  VAL B CG2 1 
ATOM   4174 N  N   . LEU B 1 56  ? 59.35221  19.16702  -51.75723 1.000 82.11836  ? 56  LEU B N   1 
ATOM   4175 C  CA  . LEU B 1 56  ? 58.66082  19.72753  -52.90593 1.000 83.23023  ? 56  LEU B CA  1 
ATOM   4176 C  C   . LEU B 1 56  ? 59.29226  21.05874  -53.28711 1.000 82.54099  ? 56  LEU B C   1 
ATOM   4177 O  O   . LEU B 1 56  ? 59.55745  21.89877  -52.42125 1.000 81.15813  ? 56  LEU B O   1 
ATOM   4178 C  CB  . LEU B 1 56  ? 57.17495  19.91418  -52.59985 1.000 79.16017  ? 56  LEU B CB  1 
ATOM   4179 C  CG  . LEU B 1 56  ? 56.36791  18.64769  -52.29707 1.000 81.27420  ? 56  LEU B CG  1 
ATOM   4180 C  CD1 . LEU B 1 56  ? 54.93705  19.00004  -51.91873 1.000 80.81176  ? 56  LEU B CD1 1 
ATOM   4181 C  CD2 . LEU B 1 56  ? 56.39304  17.70738  -53.48961 1.000 75.27173  ? 56  LEU B CD2 1 
ATOM   4182 N  N   . THR B 1 57  ? 59.53691  21.24461  -54.57999 1.000 90.97851  ? 57  THR B N   1 
ATOM   4183 C  CA  . THR B 1 57  ? 59.94346  22.55011  -55.06879 1.000 86.71679  ? 57  THR B CA  1 
ATOM   4184 C  C   . THR B 1 57  ? 58.78881  23.53336  -54.90717 1.000 84.26500  ? 57  THR B C   1 
ATOM   4185 O  O   . THR B 1 57  ? 57.63046  23.14583  -54.73103 1.000 87.16229  ? 57  THR B O   1 
ATOM   4186 C  CB  . THR B 1 57  ? 60.37676  22.48013  -56.53660 1.000 75.04892  ? 57  THR B CB  1 
ATOM   4187 O  OG1 . THR B 1 57  ? 59.21880  22.49945  -57.38047 1.000 79.35140  ? 57  THR B OG1 1 
ATOM   4188 C  CG2 . THR B 1 57  ? 61.16172  21.20506  -56.79815 1.000 86.33733  ? 57  THR B CG2 1 
ATOM   4189 N  N   . ASN B 1 58  ? 59.12074  24.82610  -54.94885 1.000 83.16450  ? 58  ASN B N   1 
ATOM   4190 C  CA  . ASN B 1 58  ? 58.09605  25.85235  -54.77872 1.000 87.03021  ? 58  ASN B CA  1 
ATOM   4191 C  C   . ASN B 1 58  ? 57.00648  25.73585  -55.83763 1.000 87.92897  ? 58  ASN B C   1 
ATOM   4192 O  O   . ASN B 1 58  ? 55.84446  26.06169  -55.57012 1.000 88.97108  ? 58  ASN B O   1 
ATOM   4193 C  CB  . ASN B 1 58  ? 58.73644  27.23998  -54.81072 1.000 76.39907  ? 58  ASN B CB  1 
ATOM   4194 C  CG  . ASN B 1 58  ? 59.68856  27.46877  -53.65114 1.000 77.95403  ? 58  ASN B CG  1 
ATOM   4195 O  OD1 . ASN B 1 58  ? 59.93654  26.56941  -52.84843 1.000 87.59367  ? 58  ASN B OD1 1 
ATOM   4196 N  ND2 . ASN B 1 58  ? 60.23166  28.67768  -53.56132 1.000 93.26501  ? 58  ASN B ND2 1 
ATOM   4197 N  N   . GLU B 1 59  ? 57.35917  25.27559  -57.04121 1.000 78.41117  ? 59  GLU B N   1 
ATOM   4198 C  CA  . GLU B 1 59  ? 56.34571  25.00775  -58.05646 1.000 82.74496  ? 59  GLU B CA  1 
ATOM   4199 C  C   . GLU B 1 59  ? 55.45697  23.83636  -57.65338 1.000 86.00863  ? 59  GLU B C   1 
ATOM   4200 O  O   . GLU B 1 59  ? 54.23330  23.89228  -57.82096 1.000 88.09698  ? 59  GLU B O   1 
ATOM   4201 C  CB  . GLU B 1 59  ? 57.00637  24.74037  -59.41011 1.000 90.71002  ? 59  GLU B CB  1 
ATOM   4202 C  CG  . GLU B 1 59  ? 57.62742  25.96744  -60.07430 1.000 88.07197  ? 59  GLU B CG  1 
ATOM   4203 C  CD  . GLU B 1 59  ? 59.04144  26.25588  -59.59812 1.000 103.72614 ? 59  GLU B CD  1 
ATOM   4204 O  OE1 . GLU B 1 59  ? 59.57852  25.46525  -58.79380 1.000 99.93502  ? 59  GLU B OE1 1 
ATOM   4205 O  OE2 . GLU B 1 59  ? 59.61940  27.27335  -60.03741 1.000 114.51930 ? 59  GLU B OE2 1 
ATOM   4206 N  N   . GLU B 1 60  ? 56.05314  22.76861  -57.11371 1.000 86.77081  ? 60  GLU B N   1 
ATOM   4207 C  CA  . GLU B 1 60  ? 55.26856  21.60845  -56.70169 1.000 71.29971  ? 60  GLU B CA  1 
ATOM   4208 C  C   . GLU B 1 60  ? 54.31278  21.94447  -55.56446 1.000 80.23806  ? 60  GLU B C   1 
ATOM   4209 O  O   . GLU B 1 60  ? 53.23172  21.35181  -55.46918 1.000 84.35102  ? 60  GLU B O   1 
ATOM   4210 C  CB  . GLU B 1 60  ? 56.19667  20.46724  -56.28319 1.000 70.29784  ? 60  GLU B CB  1 
ATOM   4211 C  CG  . GLU B 1 60  ? 57.10416  19.95794  -57.38536 1.000 79.31083  ? 60  GLU B CG  1 
ATOM   4212 C  CD  . GLU B 1 60  ? 57.90103  18.74383  -56.95537 1.000 85.84535  ? 60  GLU B CD  1 
ATOM   4213 O  OE1 . GLU B 1 60  ? 58.61739  18.82364  -55.93764 1.000 81.78683  ? 60  GLU B OE1 1 
ATOM   4214 O  OE2 . GLU B 1 60  ? 57.79812  17.70058  -57.62624 1.000 81.93906  ? 60  GLU B OE2 1 
ATOM   4215 N  N   . LYS B 1 61  ? 54.68799  22.88961  -54.69784 1.000 80.13680  ? 61  LYS B N   1 
ATOM   4216 C  CA  . LYS B 1 61  ? 53.84713  23.22645  -53.55297 1.000 81.68482  ? 61  LYS B CA  1 
ATOM   4217 C  C   . LYS B 1 61  ? 52.52166  23.84912  -53.97761 1.000 77.53397  ? 61  LYS B C   1 
ATOM   4218 O  O   . LYS B 1 61  ? 51.51850  23.70194  -53.27034 1.000 69.25593  ? 61  LYS B O   1 
ATOM   4219 C  CB  . LYS B 1 61  ? 54.59543  24.17313  -52.61308 1.000 83.93216  ? 61  LYS B CB  1 
ATOM   4220 C  CG  . LYS B 1 61  ? 55.84057  23.57521  -51.97710 1.000 78.93299  ? 61  LYS B CG  1 
ATOM   4221 C  CD  . LYS B 1 61  ? 56.54410  24.60122  -51.10113 1.000 88.95504  ? 61  LYS B CD  1 
ATOM   4222 C  CE  . LYS B 1 61  ? 57.80386  24.03510  -50.46635 1.000 98.29259  ? 61  LYS B CE  1 
ATOM   4223 N  NZ  . LYS B 1 61  ? 58.52850  25.07754  -49.68644 1.000 80.68515  ? 61  LYS B NZ  1 
ATOM   4224 N  N   . VAL B 1 62  ? 52.49545  24.55046  -55.11293 1.000 71.96951  ? 62  VAL B N   1 
ATOM   4225 C  CA  . VAL B 1 62  ? 51.25296  25.15793  -55.58484 1.000 72.45769  ? 62  VAL B CA  1 
ATOM   4226 C  C   . VAL B 1 62  ? 50.23195  24.08186  -55.93528 1.000 79.75262  ? 62  VAL B C   1 
ATOM   4227 O  O   . VAL B 1 62  ? 49.05364  24.17560  -55.57010 1.000 79.08314  ? 62  VAL B O   1 
ATOM   4228 C  CB  . VAL B 1 62  ? 51.53135  26.08630  -56.78079 1.000 69.74182  ? 62  VAL B CB  1 
ATOM   4229 C  CG1 . VAL B 1 62  ? 50.22739  26.54441  -57.41881 1.000 70.52674  ? 62  VAL B CG1 1 
ATOM   4230 C  CG2 . VAL B 1 62  ? 52.35768  27.28170  -56.33564 1.000 81.87136  ? 62  VAL B CG2 1 
ATOM   4231 N  N   . LEU B 1 63  ? 50.66960  23.04298  -56.64976 1.000 82.71274  ? 63  LEU B N   1 
ATOM   4232 C  CA  . LEU B 1 63  ? 49.77572  21.93719  -56.97877 1.000 67.72742  ? 63  LEU B CA  1 
ATOM   4233 C  C   . LEU B 1 63  ? 49.30584  21.21478  -55.72438 1.000 76.97148  ? 63  LEU B C   1 
ATOM   4234 O  O   . LEU B 1 63  ? 48.13830  20.81885  -55.62614 1.000 80.54796  ? 63  LEU B O   1 
ATOM   4235 C  CB  . LEU B 1 63  ? 50.47741  20.96512  -57.92316 1.000 61.61812  ? 63  LEU B CB  1 
ATOM   4236 C  CG  . LEU B 1 63  ? 50.59813  21.44655  -59.36625 1.000 65.17841  ? 63  LEU B CG  1 
ATOM   4237 C  CD1 . LEU B 1 63  ? 51.37048  20.43382  -60.19578 1.000 67.05251  ? 63  LEU B CD1 1 
ATOM   4238 C  CD2 . LEU B 1 63  ? 49.21505  21.70253  -59.95147 1.000 71.57324  ? 63  LEU B CD2 1 
ATOM   4239 N  N   . ASP B 1 64  ? 50.20838  21.02376  -54.76074 1.000 76.57528  ? 64  ASP B N   1 
ATOM   4240 C  CA  . ASP B 1 64  ? 49.83656  20.38909  -53.50103 1.000 70.05784  ? 64  ASP B CA  1 
ATOM   4241 C  C   . ASP B 1 64  ? 48.72714  21.16394  -52.79932 1.000 78.78133  ? 64  ASP B C   1 
ATOM   4242 O  O   . ASP B 1 64  ? 47.84778  20.56775  -52.16506 1.000 75.12823  ? 64  ASP B O   1 
ATOM   4243 C  CB  . ASP B 1 64  ? 51.06891  20.26661  -52.60333 1.000 66.37183  ? 64  ASP B CB  1 
ATOM   4244 C  CG  . ASP B 1 64  ? 50.77344  19.55877  -51.29806 1.000 72.98039  ? 64  ASP B CG  1 
ATOM   4245 O  OD1 . ASP B 1 64  ? 50.30621  18.40295  -51.34073 1.000 81.90496  ? 64  ASP B OD1 1 
ATOM   4246 O  OD2 . ASP B 1 64  ? 51.01327  20.15605  -50.22871 1.000 83.57680  ? 64  ASP B OD2 1 
ATOM   4247 N  N   . ASP B 1 65  ? 48.74862  22.49521  -52.90721 1.000 78.32227  ? 65  ASP B N   1 
ATOM   4248 C  CA  . ASP B 1 65  ? 47.73502  23.31802  -52.25554 1.000 75.55574  ? 65  ASP B CA  1 
ATOM   4249 C  C   . ASP B 1 65  ? 46.39688  23.27016  -52.98304 1.000 68.79757  ? 65  ASP B C   1 
ATOM   4250 O  O   . ASP B 1 65  ? 45.34530  23.35362  -52.33927 1.000 70.50837  ? 65  ASP B O   1 
ATOM   4251 C  CB  . ASP B 1 65  ? 48.21947  24.76695  -52.14856 1.000 88.47824  ? 65  ASP B CB  1 
ATOM   4252 C  CG  . ASP B 1 65  ? 49.44217  24.91247  -51.25822 1.000 107.04197 ? 65  ASP B CG  1 
ATOM   4253 O  OD1 . ASP B 1 65  ? 49.98430  23.87961  -50.80597 1.000 100.02581 ? 65  ASP B OD1 1 
ATOM   4254 O  OD2 . ASP B 1 65  ? 49.86023  26.06164  -51.00724 1.000 116.66976 ? 65  ASP B OD2 1 
ATOM   4255 N  N   . PHE B 1 66  ? 46.41086  23.13986  -54.31268 1.000 73.35268  ? 66  PHE B N   1 
ATOM   4256 C  CA  . PHE B 1 66  ? 45.15779  23.05275  -55.05563 1.000 76.40443  ? 66  PHE B CA  1 
ATOM   4257 C  C   . PHE B 1 66  ? 44.43824  21.73713  -54.78465 1.000 71.01980  ? 66  PHE B C   1 
ATOM   4258 O  O   . PHE B 1 66  ? 43.20360  21.70630  -54.74198 1.000 69.84713  ? 66  PHE B O   1 
ATOM   4259 C  CB  . PHE B 1 66  ? 45.41916  23.23336  -56.55310 1.000 67.91345  ? 66  PHE B CB  1 
ATOM   4260 C  CG  . PHE B 1 66  ? 44.17646  23.19060  -57.39982 1.000 69.96152  ? 66  PHE B CG  1 
ATOM   4261 C  CD1 . PHE B 1 66  ? 43.04796  23.90760  -57.03506 1.000 78.13944  ? 66  PHE B CD1 1 
ATOM   4262 C  CD2 . PHE B 1 66  ? 44.14523  22.45358  -58.57270 1.000 77.69725  ? 66  PHE B CD2 1 
ATOM   4263 C  CE1 . PHE B 1 66  ? 41.90456  23.87244  -57.81189 1.000 76.40837  ? 66  PHE B CE1 1 
ATOM   4264 C  CE2 . PHE B 1 66  ? 43.00527  22.41779  -59.35709 1.000 79.92096  ? 66  PHE B CE2 1 
ATOM   4265 C  CZ  . PHE B 1 66  ? 41.88397  23.12910  -58.97520 1.000 73.70201  ? 66  PHE B CZ  1 
ATOM   4266 N  N   . ILE B 1 67  ? 45.18235  20.64431  -54.60521 1.000 68.00146  ? 67  ILE B N   1 
ATOM   4267 C  CA  . ILE B 1 67  ? 44.55394  19.37013  -54.26704 1.000 71.35646  ? 67  ILE B CA  1 
ATOM   4268 C  C   . ILE B 1 67  ? 44.00052  19.40700  -52.84751 1.000 71.69780  ? 67  ILE B C   1 
ATOM   4269 O  O   . ILE B 1 67  ? 42.84441  19.04189  -52.60481 1.000 77.29919  ? 67  ILE B O   1 
ATOM   4270 C  CB  . ILE B 1 67  ? 45.55080  18.21128  -54.44295 1.000 67.12051  ? 67  ILE B CB  1 
ATOM   4271 C  CG1 . ILE B 1 67  ? 45.95787  18.06714  -55.90760 1.000 56.10945  ? 67  ILE B CG1 1 
ATOM   4272 C  CG2 . ILE B 1 67  ? 44.94276  16.91482  -53.94848 1.000 63.89353  ? 67  ILE B CG2 1 
ATOM   4273 C  CD1 . ILE B 1 67  ? 46.93104  16.93605  -56.15191 1.000 53.93624  ? 67  ILE B CD1 1 
ATOM   4274 N  N   . LEU B 1 68  ? 44.82396  19.84243  -51.88821 1.000 70.66821  ? 68  LEU B N   1 
ATOM   4275 C  CA  . LEU B 1 68  ? 44.40923  19.85384  -50.48807 1.000 65.53504  ? 68  LEU B CA  1 
ATOM   4276 C  C   . LEU B 1 68  ? 43.17885  20.72350  -50.26609 1.000 68.90413  ? 68  LEU B C   1 
ATOM   4277 O  O   . LEU B 1 68  ? 42.39732  20.46603  -49.34346 1.000 67.48035  ? 68  LEU B O   1 
ATOM   4278 C  CB  . LEU B 1 68  ? 45.56178  20.33253  -49.60315 1.000 61.56310  ? 68  LEU B CB  1 
ATOM   4279 C  CG  . LEU B 1 68  ? 46.61459  19.30676  -49.17381 1.000 68.38818  ? 68  LEU B CG  1 
ATOM   4280 C  CD1 . LEU B 1 68  ? 47.81694  20.00426  -48.55566 1.000 67.93327  ? 68  LEU B CD1 1 
ATOM   4281 C  CD2 . LEU B 1 68  ? 46.01794  18.30382  -48.19570 1.000 76.51113  ? 68  LEU B CD2 1 
ATOM   4282 N  N   . ALA B 1 69  ? 42.98991  21.75268  -51.09431 1.000 71.20255  ? 69  ALA B N   1 
ATOM   4283 C  CA  . ALA B 1 69  ? 41.83727  22.63420  -50.93239 1.000 62.78838  ? 69  ALA B CA  1 
ATOM   4284 C  C   . ALA B 1 69  ? 40.52872  21.88555  -51.16612 1.000 66.74905  ? 69  ALA B C   1 
ATOM   4285 O  O   . ALA B 1 69  ? 39.62309  21.91757  -50.32354 1.000 67.43498  ? 69  ALA B O   1 
ATOM   4286 C  CB  . ALA B 1 69  ? 41.95757  23.82787  -51.87894 1.000 70.86374  ? 69  ALA B CB  1 
ATOM   4287 N  N   . GLU B 1 70  ? 40.41386  21.19219  -52.30332 1.000 68.43708  ? 70  GLU B N   1 
ATOM   4288 C  CA  . GLU B 1 70  ? 39.19228  20.44250  -52.58108 1.000 66.18862  ? 70  GLU B CA  1 
ATOM   4289 C  C   . GLU B 1 70  ? 39.05711  19.23234  -51.66696 1.000 72.17071  ? 70  GLU B C   1 
ATOM   4290 O  O   . GLU B 1 70  ? 37.93830  18.84708  -51.31086 1.000 71.73260  ? 70  GLU B O   1 
ATOM   4291 C  CB  . GLU B 1 70  ? 39.16254  19.99832  -54.04517 1.000 62.63030  ? 70  GLU B CB  1 
ATOM   4292 C  CG  . GLU B 1 70  ? 37.76482  19.65915  -54.55245 1.000 74.02425  ? 70  GLU B CG  1 
ATOM   4293 C  CD  . GLU B 1 70  ? 37.76410  19.17301  -55.98807 1.000 85.18050  ? 70  GLU B CD  1 
ATOM   4294 O  OE1 . GLU B 1 70  ? 38.76781  18.55999  -56.40108 1.000 77.08164  ? 70  GLU B OE1 1 
ATOM   4295 O  OE2 . GLU B 1 70  ? 36.76366  19.40715  -56.70088 1.000 85.88108  ? 70  GLU B OE2 1 
ATOM   4296 N  N   . LYS B 1 71  ? 40.18076  18.62018  -51.29107 1.000 69.56620  ? 71  LYS B N   1 
ATOM   4297 C  CA  . LYS B 1 71  ? 40.15506  17.48128  -50.37891 1.000 58.96401  ? 71  LYS B CA  1 
ATOM   4298 C  C   . LYS B 1 71  ? 39.49649  17.84751  -49.05490 1.000 65.22514  ? 71  LYS B C   1 
ATOM   4299 O  O   . LYS B 1 71  ? 38.58772  17.15254  -48.58715 1.000 62.32188  ? 71  LYS B O   1 
ATOM   4300 C  CB  . LYS B 1 71  ? 41.58288  16.97902  -50.15598 1.000 57.31578  ? 71  LYS B CB  1 
ATOM   4301 C  CG  . LYS B 1 71  ? 41.76496  16.05876  -48.96297 1.000 63.33413  ? 71  LYS B CG  1 
ATOM   4302 C  CD  . LYS B 1 71  ? 41.61352  14.60023  -49.34666 1.000 66.64053  ? 71  LYS B CD  1 
ATOM   4303 C  CE  . LYS B 1 71  ? 42.44129  13.72540  -48.42536 1.000 60.74227  ? 71  LYS B CE  1 
ATOM   4304 N  NZ  . LYS B 1 71  ? 43.89412  14.00530  -48.60431 1.000 57.39995  ? 71  LYS B NZ  1 
ATOM   4305 N  N   . ARG B 1 72  ? 39.93696  18.94765  -48.44098 1.000 69.00714  ? 72  ARG B N   1 
ATOM   4306 C  CA  . ARG B 1 72  ? 39.41365  19.32830  -47.13319 1.000 60.54234  ? 72  ARG B CA  1 
ATOM   4307 C  C   . ARG B 1 72  ? 37.98070  19.83806  -47.22061 1.000 61.58816  ? 72  ARG B C   1 
ATOM   4308 O  O   . ARG B 1 72  ? 37.20635  19.67141  -46.27174 1.000 63.92003  ? 72  ARG B O   1 
ATOM   4309 C  CB  . ARG B 1 72  ? 40.32697  20.37580  -46.49819 1.000 49.30480  ? 72  ARG B CB  1 
ATOM   4310 C  CG  . ARG B 1 72  ? 41.71668  19.83571  -46.20873 1.000 60.12396  ? 72  ARG B CG  1 
ATOM   4311 C  CD  . ARG B 1 72  ? 42.74265  20.92957  -45.97761 1.000 57.74254  ? 72  ARG B CD  1 
ATOM   4312 N  NE  . ARG B 1 72  ? 44.02446  20.36928  -45.56608 1.000 72.80135  ? 72  ARG B NE  1 
ATOM   4313 C  CZ  . ARG B 1 72  ? 45.15647  21.05560  -45.49322 1.000 67.51972  ? 72  ARG B CZ  1 
ATOM   4314 N  NH1 . ARG B 1 72  ? 45.20682  22.34021  -45.80435 1.000 74.74439  ? 72  ARG B NH1 1 
ATOM   4315 N  NH2 . ARG B 1 72  ? 46.26767  20.43594  -45.10419 1.000 66.74193  ? 72  ARG B NH2 1 
ATOM   4316 N  N   . LYS B 1 73  ? 37.61035  20.45855  -48.34188 1.000 62.26538  ? 73  LYS B N   1 
ATOM   4317 C  CA  . LYS B 1 73  ? 36.24457  20.94642  -48.50294 1.000 67.49326  ? 73  LYS B CA  1 
ATOM   4318 C  C   . LYS B 1 73  ? 35.23912  19.80152  -48.48325 1.000 74.15872  ? 73  LYS B C   1 
ATOM   4319 O  O   . LYS B 1 73  ? 34.19371  19.89387  -47.83025 1.000 68.32940  ? 73  LYS B O   1 
ATOM   4320 C  CB  . LYS B 1 73  ? 36.13396  21.74203  -49.80278 1.000 61.76013  ? 73  LYS B CB  1 
ATOM   4321 C  CG  . LYS B 1 73  ? 34.72485  21.88690  -50.34669 1.000 61.61840  ? 73  LYS B CG  1 
ATOM   4322 C  CD  . LYS B 1 73  ? 34.76848  22.42511  -51.76769 1.000 78.66662  ? 73  LYS B CD  1 
ATOM   4323 C  CE  . LYS B 1 73  ? 33.42419  22.30370  -52.46256 1.000 80.94770  ? 73  LYS B CE  1 
ATOM   4324 N  NZ  . LYS B 1 73  ? 33.53646  22.62362  -53.91364 1.000 75.40659  ? 73  LYS B NZ  1 
ATOM   4325 N  N   . LEU B 1 74  ? 35.54109  18.70912  -49.18801 1.000 75.97036  ? 74  LEU B N   1 
ATOM   4326 C  CA  . LEU B 1 74  ? 34.61962  17.57817  -49.22562 1.000 65.13872  ? 74  LEU B CA  1 
ATOM   4327 C  C   . LEU B 1 74  ? 34.63523  16.80283  -47.91375 1.000 69.25472  ? 74  LEU B C   1 
ATOM   4328 O  O   . LEU B 1 74  ? 33.59896  16.28202  -47.48329 1.000 61.26891  ? 74  LEU B O   1 
ATOM   4329 C  CB  . LEU B 1 74  ? 34.96301  16.66549  -50.40103 1.000 64.55014  ? 74  LEU B CB  1 
ATOM   4330 C  CG  . LEU B 1 74  ? 34.81517  17.31166  -51.77915 1.000 65.58198  ? 74  LEU B CG  1 
ATOM   4331 C  CD1 . LEU B 1 74  ? 35.20982  16.33948  -52.87623 1.000 54.12108  ? 74  LEU B CD1 1 
ATOM   4332 C  CD2 . LEU B 1 74  ? 33.38986  17.80386  -51.97916 1.000 68.14250  ? 74  LEU B CD2 1 
ATOM   4333 N  N   . ILE B 1 75  ? 35.80244  16.70025  -47.27304 1.000 70.68814  ? 75  ILE B N   1 
ATOM   4334 C  CA  . ILE B 1 75  ? 35.88737  16.02492  -45.97929 1.000 67.15887  ? 75  ILE B CA  1 
ATOM   4335 C  C   . ILE B 1 75  ? 35.05200  16.76129  -44.94144 1.000 69.98120  ? 75  ILE B C   1 
ATOM   4336 O  O   . ILE B 1 75  ? 34.26356  16.15506  -44.20448 1.000 71.18830  ? 75  ILE B O   1 
ATOM   4337 C  CB  . ILE B 1 75  ? 37.35472  15.90681  -45.52919 1.000 54.01177  ? 75  ILE B CB  1 
ATOM   4338 C  CG1 . ILE B 1 75  ? 38.10483  14.88911  -46.38563 1.000 62.53872  ? 75  ILE B CG1 1 
ATOM   4339 C  CG2 . ILE B 1 75  ? 37.43109  15.52164  -44.06274 1.000 50.51622  ? 75  ILE B CG2 1 
ATOM   4340 C  CD1 . ILE B 1 75  ? 39.56720  14.76348  -46.02685 1.000 51.98600  ? 75  ILE B CD1 1 
ATOM   4341 N  N   . ASP B 1 76  ? 35.20050  18.08502  -44.88398 1.000 66.75058  ? 76  ASP B N   1 
ATOM   4342 C  CA  . ASP B 1 76  ? 34.60411  18.88833  -43.82815 1.000 62.04867  ? 76  ASP B CA  1 
ATOM   4343 C  C   . ASP B 1 76  ? 33.15395  19.26333  -44.09945 1.000 58.55205  ? 76  ASP B C   1 
ATOM   4344 O  O   . ASP B 1 76  ? 32.41694  19.55057  -43.14953 1.000 67.80500  ? 76  ASP B O   1 
ATOM   4345 C  CB  . ASP B 1 76  ? 35.44441  20.14720  -43.60633 1.000 68.15897  ? 76  ASP B CB  1 
ATOM   4346 C  CG  . ASP B 1 76  ? 36.85621  19.82569  -43.14095 1.000 70.26547  ? 76  ASP B CG  1 
ATOM   4347 O  OD1 . ASP B 1 76  ? 37.00353  18.96135  -42.25136 1.000 69.26917  ? 76  ASP B OD1 1 
ATOM   4348 O  OD2 . ASP B 1 76  ? 37.81689  20.42567  -43.67028 1.000 62.16458  ? 76  ASP B OD2 1 
ATOM   4349 N  N   . ASP B 1 77  ? 32.72269  19.27242  -45.36250 1.000 52.77095  ? 77  ASP B N   1 
ATOM   4350 C  CA  . ASP B 1 77  ? 31.30151  19.45623  -45.63866 1.000 53.18311  ? 77  ASP B CA  1 
ATOM   4351 C  C   . ASP B 1 77  ? 30.49967  18.26062  -45.14749 1.000 71.04760  ? 77  ASP B C   1 
ATOM   4352 O  O   . ASP B 1 77  ? 29.37286  18.42267  -44.66317 1.000 65.92980  ? 77  ASP B O   1 
ATOM   4353 C  CB  . ASP B 1 77  ? 31.07563  19.68476  -47.13517 1.000 54.33070  ? 77  ASP B CB  1 
ATOM   4354 C  CG  . ASP B 1 77  ? 29.63049  20.00162  -47.47652 1.000 70.86104  ? 77  ASP B CG  1 
ATOM   4355 O  OD1 . ASP B 1 77  ? 28.73276  19.17312  -47.20420 1.000 77.16869  ? 77  ASP B OD1 1 
ATOM   4356 O  OD2 . ASP B 1 77  ? 29.39250  21.09045  -48.03436 1.000 87.56970  ? 77  ASP B OD2 1 
ATOM   4357 N  N   . SER B 1 78  ? 31.07078  17.06124  -45.24319 1.000 69.59060  ? 78  SER B N   1 
ATOM   4358 C  CA  . SER B 1 78  ? 30.37096  15.85039  -44.84277 1.000 62.59102  ? 78  SER B CA  1 
ATOM   4359 C  C   . SER B 1 78  ? 30.44670  15.60074  -43.34469 1.000 61.61508  ? 78  SER B C   1 
ATOM   4360 O  O   . SER B 1 78  ? 29.51039  15.03300  -42.77002 1.000 68.18797  ? 78  SER B O   1 
ATOM   4361 C  CB  . SER B 1 78  ? 30.94076  14.64705  -45.59414 1.000 77.03370  ? 78  SER B CB  1 
ATOM   4362 O  OG  . SER B 1 78  ? 30.92736  14.87167  -46.99258 1.000 90.04726  ? 78  SER B OG  1 
ATOM   4363 N  N   . ARG B 1 79  ? 31.54089  16.00807  -42.69895 1.000 59.87739  ? 79  ARG B N   1 
ATOM   4364 C  CA  . ARG B 1 79  ? 31.66050  15.80754  -41.25979 1.000 56.39344  ? 79  ARG B CA  1 
ATOM   4365 C  C   . ARG B 1 79  ? 30.70894  16.71953  -40.49417 1.000 58.57775  ? 79  ARG B C   1 
ATOM   4366 O  O   . ARG B 1 79  ? 30.12678  16.30696  -39.48538 1.000 62.17164  ? 79  ARG B O   1 
ATOM   4367 C  CB  . ARG B 1 79  ? 33.10933  16.03261  -40.82012 1.000 49.26044  ? 79  ARG B CB  1 
ATOM   4368 C  CG  . ARG B 1 79  ? 33.38710  15.70485  -39.35844 1.000 56.49531  ? 79  ARG B CG  1 
ATOM   4369 C  CD  . ARG B 1 79  ? 34.85867  15.89994  -39.01932 1.000 62.15825  ? 79  ARG B CD  1 
ATOM   4370 N  NE  . ARG B 1 79  ? 35.26390  17.29610  -39.13068 1.000 73.58834  ? 79  ARG B NE  1 
ATOM   4371 C  CZ  . ARG B 1 79  ? 35.23416  18.16603  -38.13035 1.000 74.95604  ? 79  ARG B CZ  1 
ATOM   4372 N  NH1 . ARG B 1 79  ? 34.82342  17.81616  -36.92237 1.000 74.83945  ? 79  ARG B NH1 1 
ATOM   4373 N  NH2 . ARG B 1 79  ? 35.62818  19.41759  -38.34671 1.000 65.56326  ? 79  ARG B NH2 1 
ATOM   4374 N  N   . LEU B 1 80  ? 30.52339  17.95308  -40.96828 1.000 66.58960  ? 80  LEU B N   1 
ATOM   4375 C  CA  . LEU B 1 80  ? 29.78718  18.98647  -40.24393 1.000 56.83938  ? 80  LEU B CA  1 
ATOM   4376 C  C   . LEU B 1 80  ? 28.34904  19.17011  -40.73295 1.000 58.19965  ? 80  LEU B C   1 
ATOM   4377 O  O   . LEU B 1 80  ? 27.42436  19.18220  -39.91488 1.000 63.44119  ? 80  LEU B O   1 
ATOM   4378 C  CB  . LEU B 1 80  ? 30.57268  20.30544  -40.31622 1.000 49.50036  ? 80  LEU B CB  1 
ATOM   4379 C  CG  . LEU B 1 80  ? 31.97079  20.21611  -39.69077 1.000 55.86891  ? 80  LEU B CG  1 
ATOM   4380 C  CD1 . LEU B 1 80  ? 32.80001  21.44436  -40.01527 1.000 72.08102  ? 80  LEU B CD1 1 
ATOM   4381 C  CD2 . LEU B 1 80  ? 31.87490  20.02712  -38.18380 1.000 63.59716  ? 80  LEU B CD2 1 
ATOM   4382 N  N   . ASN B 1 81  ? 28.12247  19.29897  -42.04599 1.000 59.33818  ? 81  ASN B N   1 
ATOM   4383 C  CA  . ASN B 1 81  ? 26.75036  19.31310  -42.54441 1.000 65.51852  ? 81  ASN B CA  1 
ATOM   4384 C  C   . ASN B 1 81  ? 26.07340  17.95120  -42.41191 1.000 67.99279  ? 81  ASN B C   1 
ATOM   4385 O  O   . ASN B 1 81  ? 24.86630  17.84983  -42.66416 1.000 69.00223  ? 81  ASN B O   1 
ATOM   4386 C  CB  . ASN B 1 81  ? 26.69944  19.71479  -44.02301 1.000 70.50118  ? 81  ASN B CB  1 
ATOM   4387 C  CG  . ASN B 1 81  ? 26.76317  21.20084  -44.24558 1.000 83.80993  ? 81  ASN B CG  1 
ATOM   4388 O  OD1 . ASN B 1 81  ? 25.80596  21.93283  -43.94390 1.000 84.46649  ? 81  ASN B OD1 1 
ATOM   4389 N  ND2 . ASN B 1 81  ? 27.91579  21.66233  -44.78813 1.000 92.42800  ? 81  ASN B ND2 1 
ATOM   4390 N  N   . GLN B 1 82  ? 26.83986  16.90361  -42.09482 1.000 71.73227  ? 82  GLN B N   1 
ATOM   4391 C  CA  . GLN B 1 82  ? 26.33502  15.54411  -41.92742 1.000 62.93377  ? 82  GLN B CA  1 
ATOM   4392 C  C   . GLN B 1 82  ? 25.68155  15.04456  -43.21453 1.000 65.79867  ? 82  GLN B C   1 
ATOM   4393 O  O   . GLN B 1 82  ? 24.47760  14.80099  -43.28675 1.000 58.94835  ? 82  GLN B O   1 
ATOM   4394 C  CB  . GLN B 1 82  ? 25.36956  15.44489  -40.74300 1.000 62.56755  ? 82  GLN B CB  1 
ATOM   4395 C  CG  . GLN B 1 82  ? 26.03740  15.37226  -39.37801 1.000 69.66901  ? 82  GLN B CG  1 
ATOM   4396 C  CD  . GLN B 1 82  ? 25.05249  15.08716  -38.25141 1.000 85.66550  ? 82  GLN B CD  1 
ATOM   4397 O  OE1 . GLN B 1 82  ? 24.89247  13.94189  -37.82507 1.000 85.23550  ? 82  GLN B OE1 1 
ATOM   4398 N  NE2 . GLN B 1 82  ? 24.39203  16.13174  -37.76218 1.000 76.23055  ? 82  GLN B NE2 1 
ATOM   4399 N  N   . THR B 1 83  ? 26.50779  14.92849  -44.25174 1.000 68.16818  ? 83  THR B N   1 
ATOM   4400 C  CA  . THR B 1 83  ? 26.09005  14.40973  -45.54417 1.000 63.08717  ? 83  THR B CA  1 
ATOM   4401 C  C   . THR B 1 83  ? 27.05869  13.31273  -45.97533 1.000 71.03505  ? 83  THR B C   1 
ATOM   4402 O  O   . THR B 1 83  ? 28.02943  12.99774  -45.27909 1.000 77.98076  ? 83  THR B O   1 
ATOM   4403 C  CB  . THR B 1 83  ? 26.01434  15.52202  -46.59839 1.000 72.82081  ? 83  THR B CB  1 
ATOM   4404 O  OG1 . THR B 1 83  ? 27.24643  16.25368  -46.61917 1.000 81.80137  ? 83  THR B OG1 1 
ATOM   4405 C  CG2 . THR B 1 83  ? 24.86165  16.47077  -46.29984 1.000 70.90903  ? 83  THR B CG2 1 
ATOM   4406 N  N   . GLU B 1 84  ? 26.79846  12.72673  -47.14117 1.000 66.78435  ? 84  GLU B N   1 
ATOM   4407 C  CA  . GLU B 1 84  ? 27.57766  11.58083  -47.59017 1.000 62.89465  ? 84  GLU B CA  1 
ATOM   4408 C  C   . GLU B 1 84  ? 28.88222  12.02146  -48.24371 1.000 65.28427  ? 84  GLU B C   1 
ATOM   4409 O  O   . GLU B 1 84  ? 28.91654  12.97716  -49.02373 1.000 77.67670  ? 84  GLU B O   1 
ATOM   4410 C  CB  . GLU B 1 84  ? 26.76817  10.72520  -48.56289 1.000 75.84921  ? 84  GLU B CB  1 
ATOM   4411 C  CG  . GLU B 1 84  ? 27.38256  9.35633   -48.81756 1.000 96.96125  ? 84  GLU B CG  1 
ATOM   4412 C  CD  . GLU B 1 84  ? 26.56867  8.51196   -49.77579 1.000 93.27116  ? 84  GLU B CD  1 
ATOM   4413 O  OE1 . GLU B 1 84  ? 25.76553  9.08119   -50.54607 1.000 84.36023  ? 84  GLU B OE1 1 
ATOM   4414 O  OE2 . GLU B 1 84  ? 26.73080  7.27405   -49.75135 1.000 92.26124  ? 84  GLU B OE2 1 
ATOM   4415 N  N   . TYR B 1 85  ? 29.95962  11.30906  -47.91473 1.000 70.06288  ? 85  TYR B N   1 
ATOM   4416 C  CA  . TYR B 1 85  ? 31.28635  11.53905  -48.48711 1.000 55.16794  ? 85  TYR B CA  1 
ATOM   4417 C  C   . TYR B 1 85  ? 31.42759  10.61197  -49.68863 1.000 56.90960  ? 85  TYR B C   1 
ATOM   4418 O  O   . TYR B 1 85  ? 31.89142  9.47697   -49.57647 1.000 65.45592  ? 85  TYR B O   1 
ATOM   4419 C  CB  . TYR B 1 85  ? 32.35971  11.29925  -47.43133 1.000 57.86484  ? 85  TYR B CB  1 
ATOM   4420 C  CG  . TYR B 1 85  ? 33.78475  11.58277  -47.84931 1.000 49.99502  ? 85  TYR B CG  1 
ATOM   4421 C  CD1 . TYR B 1 85  ? 34.15011  12.81447  -48.37518 1.000 54.47807  ? 85  TYR B CD1 1 
ATOM   4422 C  CD2 . TYR B 1 85  ? 34.77514  10.62578  -47.67574 1.000 58.79235  ? 85  TYR B CD2 1 
ATOM   4423 C  CE1 . TYR B 1 85  ? 35.46097  13.07320  -48.73910 1.000 57.02805  ? 85  TYR B CE1 1 
ATOM   4424 C  CE2 . TYR B 1 85  ? 36.08308  10.87431  -48.03439 1.000 46.01885  ? 85  TYR B CE2 1 
ATOM   4425 C  CZ  . TYR B 1 85  ? 36.42133  12.09781  -48.56505 1.000 50.32361  ? 85  TYR B CZ  1 
ATOM   4426 O  OH  . TYR B 1 85  ? 37.72584  12.34439  -48.92175 1.000 56.66407  ? 85  TYR B OH  1 
ATOM   4427 N  N   . MET B 1 86  ? 31.00954  11.10741  -50.85715 1.000 59.51478  ? 86  MET B N   1 
ATOM   4428 C  CA  . MET B 1 86  ? 30.97369  10.35712  -52.11137 1.000 60.94989  ? 86  MET B CA  1 
ATOM   4429 C  C   . MET B 1 86  ? 32.30158  9.69276   -52.48021 1.000 56.10134  ? 86  MET B C   1 
ATOM   4430 O  O   . MET B 1 86  ? 32.28036  8.60303   -53.06672 1.000 57.61409  ? 86  MET B O   1 
ATOM   4431 C  CB  . MET B 1 86  ? 30.51434  11.26125  -53.25801 1.000 60.92475  ? 86  MET B CB  1 
ATOM   4432 C  CG  . MET B 1 86  ? 29.09529  11.78613  -53.10027 1.000 65.74141  ? 86  MET B CG  1 
ATOM   4433 S  SD  . MET B 1 86  ? 27.85521  10.47836  -52.98981 1.000 81.68749  ? 86  MET B SD  1 
ATOM   4434 C  CE  . MET B 1 86  ? 27.83419  9.86105   -54.67073 1.000 55.68328  ? 86  MET B CE  1 
ATOM   4435 N  N   . PRO B 1 87  ? 33.46681  10.29534  -52.19386 1.000 56.07698  ? 87  PRO B N   1 
ATOM   4436 C  CA  . PRO B 1 87  ? 34.72501  9.58646   -52.48968 1.000 56.97038  ? 87  PRO B CA  1 
ATOM   4437 C  C   . PRO B 1 87  ? 34.82268  8.20668   -51.85612 1.000 56.10859  ? 87  PRO B C   1 
ATOM   4438 O  O   . PRO B 1 87  ? 35.52743  7.34251   -52.39263 1.000 57.41237  ? 87  PRO B O   1 
ATOM   4439 C  CB  . PRO B 1 87  ? 35.79392  10.53855  -51.93822 1.000 48.09747  ? 87  PRO B CB  1 
ATOM   4440 C  CG  . PRO B 1 87  ? 35.19927  11.87569  -52.12233 1.000 51.49398  ? 87  PRO B CG  1 
ATOM   4441 C  CD  . PRO B 1 87  ? 33.72318  11.71497  -51.87811 1.000 50.43571  ? 87  PRO B CD  1 
ATOM   4442 N  N   . ALA B 1 88  ? 34.13134  7.96180   -50.74470 1.000 56.91592  ? 88  ALA B N   1 
ATOM   4443 C  CA  . ALA B 1 88  ? 34.17727  6.67155   -50.06992 1.000 57.14632  ? 88  ALA B CA  1 
ATOM   4444 C  C   . ALA B 1 88  ? 32.95626  5.80744   -50.36112 1.000 61.15178  ? 88  ALA B C   1 
ATOM   4445 O  O   . ALA B 1 88  ? 32.75921  4.78748   -49.69439 1.000 72.76009  ? 88  ALA B O   1 
ATOM   4446 C  CB  . ALA B 1 88  ? 34.32826  6.87181   -48.56156 1.000 52.76307  ? 88  ALA B CB  1 
ATOM   4447 N  N   . ALA B 1 89  ? 32.13789  6.18511   -51.33990 1.000 48.81735  ? 89  ALA B N   1 
ATOM   4448 C  CA  . ALA B 1 89  ? 30.93269  5.43916   -51.65937 1.000 60.36734  ? 89  ALA B CA  1 
ATOM   4449 C  C   . ALA B 1 89  ? 31.23920  4.34345   -52.67882 1.000 64.08349  ? 89  ALA B C   1 
ATOM   4450 O  O   . ALA B 1 89  ? 32.37892  4.16242   -53.11432 1.000 69.51027  ? 89  ALA B O   1 
ATOM   4451 C  CB  . ALA B 1 89  ? 29.84620  6.38179   -52.17296 1.000 65.56299  ? 89  ALA B CB  1 
ATOM   4452 N  N   . SER B 1 90  ? 30.20399  3.59510   -53.05733 1.000 56.42969  ? 90  SER B N   1 
ATOM   4453 C  CA  . SER B 1 90  ? 30.34017  2.61184   -54.12339 1.000 61.59796  ? 90  SER B CA  1 
ATOM   4454 C  C   . SER B 1 90  ? 30.78327  3.29722   -55.40916 1.000 67.92705  ? 90  SER B C   1 
ATOM   4455 O  O   . SER B 1 90  ? 30.33264  4.40023   -55.72726 1.000 69.04014  ? 90  SER B O   1 
ATOM   4456 C  CB  . SER B 1 90  ? 29.01370  1.88146   -54.34339 1.000 62.64503  ? 90  SER B CB  1 
ATOM   4457 O  OG  . SER B 1 90  ? 29.03157  1.14497   -55.55354 1.000 74.40346  ? 90  SER B OG  1 
ATOM   4458 N  N   . PHE B 1 91  ? 31.68513  2.64399   -56.14773 1.000 62.24565  ? 91  PHE B N   1 
ATOM   4459 C  CA  . PHE B 1 91  ? 32.21434  3.25657   -57.36093 1.000 60.33191  ? 91  PHE B CA  1 
ATOM   4460 C  C   . PHE B 1 91  ? 31.14153  3.45540   -58.42359 1.000 62.41594  ? 91  PHE B C   1 
ATOM   4461 O  O   . PHE B 1 91  ? 31.33253  4.26503   -59.33640 1.000 66.15037  ? 91  PHE B O   1 
ATOM   4462 C  CB  . PHE B 1 91  ? 33.36628  2.42293   -57.92442 1.000 59.15338  ? 91  PHE B CB  1 
ATOM   4463 C  CG  . PHE B 1 91  ? 34.11041  3.10499   -59.03529 1.000 59.77982  ? 91  PHE B CG  1 
ATOM   4464 C  CD1 . PHE B 1 91  ? 34.91140  4.20425   -58.77524 1.000 58.58282  ? 91  PHE B CD1 1 
ATOM   4465 C  CD2 . PHE B 1 91  ? 34.00385  2.65476   -60.33904 1.000 66.01263  ? 91  PHE B CD2 1 
ATOM   4466 C  CE1 . PHE B 1 91  ? 35.59369  4.84038   -59.79573 1.000 65.80954  ? 91  PHE B CE1 1 
ATOM   4467 C  CE2 . PHE B 1 91  ? 34.68423  3.28553   -61.36396 1.000 60.60316  ? 91  PHE B CE2 1 
ATOM   4468 C  CZ  . PHE B 1 91  ? 35.48060  4.37913   -61.09156 1.000 57.66875  ? 91  PHE B CZ  1 
ATOM   4469 N  N   . TYR B 1 92  ? 30.02102  2.73812   -58.32649 1.000 54.67377  ? 92  TYR B N   1 
ATOM   4470 C  CA  . TYR B 1 92  ? 28.88526  3.01828   -59.19873 1.000 62.82865  ? 92  TYR B CA  1 
ATOM   4471 C  C   . TYR B 1 92  ? 28.36662  4.43284   -58.97878 1.000 71.00765  ? 92  TYR B C   1 
ATOM   4472 O  O   . TYR B 1 92  ? 28.01502  5.13383   -59.93515 1.000 73.72238  ? 92  TYR B O   1 
ATOM   4473 C  CB  . TYR B 1 92  ? 27.77987  1.99236   -58.94665 1.000 67.43308  ? 92  TYR B CB  1 
ATOM   4474 C  CG  . TYR B 1 92  ? 26.49415  2.22068   -59.71258 1.000 60.07943  ? 92  TYR B CG  1 
ATOM   4475 C  CD1 . TYR B 1 92  ? 26.32892  1.72084   -60.99674 1.000 56.63443  ? 92  TYR B CD1 1 
ATOM   4476 C  CD2 . TYR B 1 92  ? 25.43415  2.91038   -59.13621 1.000 64.16813  ? 92  TYR B CD2 1 
ATOM   4477 C  CE1 . TYR B 1 92  ? 25.15002  1.91649   -61.69196 1.000 59.75002  ? 92  TYR B CE1 1 
ATOM   4478 C  CE2 . TYR B 1 92  ? 24.25503  3.11093   -59.82259 1.000 58.91380  ? 92  TYR B CE2 1 
ATOM   4479 C  CZ  . TYR B 1 92  ? 24.11709  2.61325   -61.09815 1.000 59.17902  ? 92  TYR B CZ  1 
ATOM   4480 O  OH  . TYR B 1 92  ? 22.93889  2.81493   -61.77852 1.000 68.13014  ? 92  TYR B OH  1 
ATOM   4481 N  N   . ARG B 1 93  ? 28.31589  4.86798   -57.72284 1.000 75.34440  ? 93  ARG B N   1 
ATOM   4482 C  CA  . ARG B 1 93  ? 27.76361  6.16725   -57.36978 1.000 59.82417  ? 93  ARG B CA  1 
ATOM   4483 C  C   . ARG B 1 93  ? 28.81795  7.26129   -57.29184 1.000 58.90301  ? 93  ARG B C   1 
ATOM   4484 O  O   . ARG B 1 93  ? 28.48978  8.43891   -57.47173 1.000 68.42285  ? 93  ARG B O   1 
ATOM   4485 C  CB  . ARG B 1 93  ? 27.01395  6.05500   -56.03985 1.000 57.51211  ? 93  ARG B CB  1 
ATOM   4486 C  CG  . ARG B 1 93  ? 26.01843  4.90006   -56.02541 1.000 71.05980  ? 93  ARG B CG  1 
ATOM   4487 C  CD  . ARG B 1 93  ? 25.32710  4.72411   -54.68209 1.000 67.59028  ? 93  ARG B CD  1 
ATOM   4488 N  NE  . ARG B 1 93  ? 24.59749  5.91720   -54.27555 1.000 66.79351  ? 93  ARG B NE  1 
ATOM   4489 C  CZ  . ARG B 1 93  ? 24.94733  6.69743   -53.26266 1.000 79.88536  ? 93  ARG B CZ  1 
ATOM   4490 N  NH1 . ARG B 1 93  ? 25.99812  6.42049   -52.50829 1.000 81.76317  ? 93  ARG B NH1 1 
ATOM   4491 N  NH2 . ARG B 1 93  ? 24.22186  7.78027   -52.99642 1.000 79.00892  ? 93  ARG B NH2 1 
ATOM   4492 N  N   . SER B 1 94  ? 30.07493  6.90803   -57.03075 1.000 59.98331  ? 94  SER B N   1 
ATOM   4493 C  CA  . SER B 1 94  ? 31.12252  7.91594   -56.93431 1.000 53.71445  ? 94  SER B CA  1 
ATOM   4494 C  C   . SER B 1 94  ? 31.72107  8.27506   -58.28529 1.000 59.67687  ? 94  SER B C   1 
ATOM   4495 O  O   . SER B 1 94  ? 32.30424  9.35436   -58.41583 1.000 62.68065  ? 94  SER B O   1 
ATOM   4496 C  CB  . SER B 1 94  ? 32.23723  7.44318   -55.99911 1.000 51.43908  ? 94  SER B CB  1 
ATOM   4497 O  OG  . SER B 1 94  ? 32.97237  6.38168   -56.57882 1.000 63.47796  ? 94  SER B OG  1 
ATOM   4498 N  N   . LYS B 1 95  ? 31.59918  7.39843   -59.28475 1.000 62.05247  ? 95  LYS B N   1 
ATOM   4499 C  CA  . LYS B 1 95  ? 32.24529  7.64384   -60.57164 1.000 61.40200  ? 95  LYS B CA  1 
ATOM   4500 C  C   . LYS B 1 95  ? 31.69518  8.89820   -61.23857 1.000 72.12730  ? 95  LYS B C   1 
ATOM   4501 O  O   . LYS B 1 95  ? 32.45512  9.71877   -61.76597 1.000 74.12537  ? 95  LYS B O   1 
ATOM   4502 C  CB  . LYS B 1 95  ? 32.07541  6.43190   -61.48565 1.000 62.03633  ? 95  LYS B CB  1 
ATOM   4503 C  CG  . LYS B 1 95  ? 32.78676  6.56729   -62.82276 1.000 55.48949  ? 95  LYS B CG  1 
ATOM   4504 C  CD  . LYS B 1 95  ? 32.52784  5.36659   -63.71902 1.000 50.99620  ? 95  LYS B CD  1 
ATOM   4505 C  CE  . LYS B 1 95  ? 32.97119  5.63900   -65.14958 1.000 57.44663  ? 95  LYS B CE  1 
ATOM   4506 N  NZ  . LYS B 1 95  ? 32.63025  4.50814   -66.05655 1.000 62.84493  ? 95  LYS B NZ  1 
ATOM   4507 N  N   . ASP B 1 96  ? 30.36934  9.05766   -61.23501 1.000 71.60717  ? 96  ASP B N   1 
ATOM   4508 C  CA  . ASP B 1 96  ? 29.76817  10.25492  -61.81430 1.000 76.41103  ? 96  ASP B CA  1 
ATOM   4509 C  C   . ASP B 1 96  ? 30.23502  11.51092  -61.08988 1.000 78.99235  ? 96  ASP B C   1 
ATOM   4510 O  O   . ASP B 1 96  ? 30.50766  12.53845  -61.72223 1.000 76.31080  ? 96  ASP B O   1 
ATOM   4511 C  CB  . ASP B 1 96  ? 28.24370  10.14802  -61.77398 1.000 80.02151  ? 96  ASP B CB  1 
ATOM   4512 C  CG  . ASP B 1 96  ? 27.70279  9.12444   -62.75276 1.000 81.54409  ? 96  ASP B CG  1 
ATOM   4513 O  OD1 . ASP B 1 96  ? 28.51248  8.47820   -63.44979 1.000 87.72093  ? 96  ASP B OD1 1 
ATOM   4514 O  OD2 . ASP B 1 96  ? 26.46545  8.96880   -62.82780 1.000 85.69833  ? 96  ASP B OD2 1 
ATOM   4515 N  N   . PHE B 1 97  ? 30.32454  11.44704  -59.76037 1.000 79.00839  ? 97  PHE B N   1 
ATOM   4516 C  CA  . PHE B 1 97  ? 30.79390  12.58848  -58.98206 1.000 66.50777  ? 97  PHE B CA  1 
ATOM   4517 C  C   . PHE B 1 97  ? 32.26472  12.88489  -59.25656 1.000 66.85371  ? 97  PHE B C   1 
ATOM   4518 O  O   . PHE B 1 97  ? 32.64646  14.04285  -59.46459 1.000 74.53049  ? 97  PHE B O   1 
ATOM   4519 C  CB  . PHE B 1 97  ? 30.56386  12.32386  -57.49372 1.000 53.12377  ? 97  PHE B CB  1 
ATOM   4520 C  CG  . PHE B 1 97  ? 31.35198  13.22491  -56.58804 1.000 62.49532  ? 97  PHE B CG  1 
ATOM   4521 C  CD1 . PHE B 1 97  ? 30.89974  14.49960  -56.29455 1.000 63.00517  ? 97  PHE B CD1 1 
ATOM   4522 C  CD2 . PHE B 1 97  ? 32.54269  12.79413  -56.02306 1.000 66.08479  ? 97  PHE B CD2 1 
ATOM   4523 C  CE1 . PHE B 1 97  ? 31.62287  15.33122  -55.46093 1.000 51.47194  ? 97  PHE B CE1 1 
ATOM   4524 C  CE2 . PHE B 1 97  ? 33.26971  13.62166  -55.19046 1.000 64.67038  ? 97  PHE B CE2 1 
ATOM   4525 C  CZ  . PHE B 1 97  ? 32.80771  14.89080  -54.90872 1.000 56.60073  ? 97  PHE B CZ  1 
ATOM   4526 N  N   . ILE B 1 98  ? 33.10423  11.84454  -59.25957 1.000 66.52179  ? 98  ILE B N   1 
ATOM   4527 C  CA  . ILE B 1 98  ? 34.54825  12.01959  -59.40211 1.000 68.57222  ? 98  ILE B CA  1 
ATOM   4528 C  C   . ILE B 1 98  ? 34.89280  12.69327  -60.72439 1.000 68.74527  ? 98  ILE B C   1 
ATOM   4529 O  O   . ILE B 1 98  ? 35.85017  13.47392  -60.80362 1.000 64.11357  ? 98  ILE B O   1 
ATOM   4530 C  CB  . ILE B 1 98  ? 35.25598  10.65512  -59.24715 1.000 67.11320  ? 98  ILE B CB  1 
ATOM   4531 C  CG1 . ILE B 1 98  ? 35.22172  10.19901  -57.78518 1.000 74.57547  ? 98  ILE B CG1 1 
ATOM   4532 C  CG2 . ILE B 1 98  ? 36.69166  10.71117  -59.75912 1.000 63.08417  ? 98  ILE B CG2 1 
ATOM   4533 C  CD1 . ILE B 1 98  ? 35.77969  8.80794   -57.55797 1.000 52.79675  ? 98  ILE B CD1 1 
ATOM   4534 N  N   . ASP B 1 99  ? 34.11379  12.43316  -61.77042 1.000 75.76851  ? 99  ASP B N   1 
ATOM   4535 C  CA  . ASP B 1 99  ? 34.37931  12.99965  -63.08583 1.000 71.91260  ? 99  ASP B CA  1 
ATOM   4536 C  C   . ASP B 1 99  ? 33.90007  14.44232  -63.22643 1.000 75.46335  ? 99  ASP B C   1 
ATOM   4537 O  O   . ASP B 1 99  ? 33.83954  14.94772  -64.35220 1.000 85.18662  ? 99  ASP B O   1 
ATOM   4538 C  CB  . ASP B 1 99  ? 33.74366  12.12716  -64.17017 1.000 87.66952  ? 99  ASP B CB  1 
ATOM   4539 C  CG  . ASP B 1 99  ? 34.36636  10.74433  -64.24348 1.000 92.07111  ? 99  ASP B CG  1 
ATOM   4540 O  OD1 . ASP B 1 99  ? 35.32192  10.48039  -63.48225 1.000 82.54240  ? 99  ASP B OD1 1 
ATOM   4541 O  OD2 . ASP B 1 99  ? 33.90300  9.92131   -65.06156 1.000 83.25478  ? 99  ASP B OD2 1 
ATOM   4542 N  N   . THR B 1 100 ? 33.53639  15.10432  -62.12171 1.000 79.75884  ? 100 THR B N   1 
ATOM   4543 C  CA  . THR B 1 100 ? 33.24874  16.53542  -62.12622 1.000 68.87593  ? 100 THR B CA  1 
ATOM   4544 C  C   . THR B 1 100 ? 34.04079  17.26747  -61.04703 1.000 65.45134  ? 100 THR B C   1 
ATOM   4545 O  O   . THR B 1 100 ? 33.64101  18.35766  -60.62433 1.000 71.17995  ? 100 THR B O   1 
ATOM   4546 C  CB  . THR B 1 100 ? 31.75106  16.81186  -61.94550 1.000 66.63722  ? 100 THR B CB  1 
ATOM   4547 O  OG1 . THR B 1 100 ? 31.35012  16.46122  -60.61473 1.000 63.07551  ? 100 THR B OG1 1 
ATOM   4548 C  CG2 . THR B 1 100 ? 30.92390  16.01847  -62.94928 1.000 72.18555  ? 100 THR B CG2 1 
ATOM   4549 N  N   . THR B 1 101 ? 35.15203  16.69386  -60.59281 1.000 59.57284  ? 101 THR B N   1 
ATOM   4550 C  CA  . THR B 1 101 ? 35.98318  17.28370  -59.55350 1.000 65.39956  ? 101 THR B CA  1 
ATOM   4551 C  C   . THR B 1 101 ? 37.27388  17.81339  -60.16295 1.000 69.17447  ? 101 THR B C   1 
ATOM   4552 O  O   . THR B 1 101 ? 37.83112  17.20893  -61.08485 1.000 64.97766  ? 101 THR B O   1 
ATOM   4553 C  CB  . THR B 1 101 ? 36.30975  16.26545  -58.45743 1.000 71.88029  ? 101 THR B CB  1 
ATOM   4554 O  OG1 . THR B 1 101 ? 37.14132  15.23141  -58.99678 1.000 74.53825  ? 101 THR B OG1 1 
ATOM   4555 C  CG2 . THR B 1 101 ? 35.03357  15.64833  -57.90634 1.000 73.15134  ? 101 THR B CG2 1 
ATOM   4556 N  N   . PHE B 1 102 ? 37.74292  18.94936  -59.64183 1.000 77.56482  ? 102 PHE B N   1 
ATOM   4557 C  CA  . PHE B 1 102 ? 38.93717  19.58948  -60.18077 1.000 65.20285  ? 102 PHE B CA  1 
ATOM   4558 C  C   . PHE B 1 102 ? 40.21062  18.81580  -59.86239 1.000 66.09321  ? 102 PHE B C   1 
ATOM   4559 O  O   . PHE B 1 102 ? 41.22435  19.01090  -60.54134 1.000 72.96136  ? 102 PHE B O   1 
ATOM   4560 C  CB  . PHE B 1 102 ? 39.04757  21.01933  -59.64560 1.000 61.37399  ? 102 PHE B CB  1 
ATOM   4561 C  CG  . PHE B 1 102 ? 37.84242  21.87244  -59.93690 1.000 65.52383  ? 102 PHE B CG  1 
ATOM   4562 C  CD1 . PHE B 1 102 ? 37.15870  21.74456  -61.13474 1.000 74.34611  ? 102 PHE B CD1 1 
ATOM   4563 C  CD2 . PHE B 1 102 ? 37.38940  22.79683  -59.00907 1.000 65.01797  ? 102 PHE B CD2 1 
ATOM   4564 C  CE1 . PHE B 1 102 ? 36.04863  22.52581  -61.40541 1.000 66.91720  ? 102 PHE B CE1 1 
ATOM   4565 C  CE2 . PHE B 1 102 ? 36.27829  23.58031  -59.27393 1.000 78.03027  ? 102 PHE B CE2 1 
ATOM   4566 C  CZ  . PHE B 1 102 ? 35.60856  23.44454  -60.47408 1.000 64.08334  ? 102 PHE B CZ  1 
ATOM   4567 N  N   . ALA B 1 103 ? 40.18638  17.94990  -58.84729 1.000 56.53035  ? 103 ALA B N   1 
ATOM   4568 C  CA  . ALA B 1 103 ? 41.38152  17.19830  -58.48271 1.000 53.29347  ? 103 ALA B CA  1 
ATOM   4569 C  C   . ALA B 1 103 ? 41.62402  16.01639  -59.41079 1.000 58.63610  ? 103 ALA B C   1 
ATOM   4570 O  O   . ALA B 1 103 ? 42.78145  15.67426  -59.67932 1.000 68.54820  ? 103 ALA B O   1 
ATOM   4571 C  CB  . ALA B 1 103 ? 41.28261  16.71270  -57.03665 1.000 53.77839  ? 103 ALA B CB  1 
ATOM   4572 N  N   . TYR B 1 104 ? 40.55751  15.37949  -59.90149 1.000 68.36023  ? 104 TYR B N   1 
ATOM   4573 C  CA  . TYR B 1 104 ? 40.72978  14.22702  -60.77907 1.000 69.63589  ? 104 TYR B CA  1 
ATOM   4574 C  C   . TYR B 1 104 ? 41.43582  14.60570  -62.07339 1.000 68.54612  ? 104 TYR B C   1 
ATOM   4575 O  O   . TYR B 1 104 ? 42.17877  13.79232  -62.63272 1.000 72.14085  ? 104 TYR B O   1 
ATOM   4576 C  CB  . TYR B 1 104 ? 39.37554  13.58326  -61.07468 1.000 57.23598  ? 104 TYR B CB  1 
ATOM   4577 C  CG  . TYR B 1 104 ? 39.46857  12.34938  -61.94040 1.000 61.68807  ? 104 TYR B CG  1 
ATOM   4578 C  CD1 . TYR B 1 104 ? 40.31384  11.30260  -61.59764 1.000 70.99082  ? 104 TYR B CD1 1 
ATOM   4579 C  CD2 . TYR B 1 104 ? 38.70564  12.22631  -63.09260 1.000 65.21531  ? 104 TYR B CD2 1 
ATOM   4580 C  CE1 . TYR B 1 104 ? 40.40209  10.17271  -62.38141 1.000 69.88010  ? 104 TYR B CE1 1 
ATOM   4581 C  CE2 . TYR B 1 104 ? 38.78650  11.09868  -63.88204 1.000 75.13648  ? 104 TYR B CE2 1 
ATOM   4582 C  CZ  . TYR B 1 104 ? 39.63774  10.07631  -63.52168 1.000 69.25692  ? 104 TYR B CZ  1 
ATOM   4583 O  OH  . TYR B 1 104 ? 39.72158  8.95354   -64.30506 1.000 68.43817  ? 104 TYR B OH  1 
ATOM   4584 N  N   . LYS B 1 105 ? 41.21557  15.82700  -62.56612 1.000 66.90084  ? 105 LYS B N   1 
ATOM   4585 C  CA  . LYS B 1 105 ? 41.91520  16.27780  -63.76440 1.000 54.51423  ? 105 LYS B CA  1 
ATOM   4586 C  C   . LYS B 1 105 ? 43.39719  16.50839  -63.49815 1.000 58.33581  ? 105 LYS B C   1 
ATOM   4587 O  O   . LYS B 1 105 ? 44.22634  16.28624  -64.38806 1.000 64.51650  ? 105 LYS B O   1 
ATOM   4588 C  CB  . LYS B 1 105 ? 41.26922  17.55478  -64.30074 1.000 55.22489  ? 105 LYS B CB  1 
ATOM   4589 N  N   . ILE B 1 106 ? 43.74663  16.96435  -62.29299 1.000 58.89612  ? 106 ILE B N   1 
ATOM   4590 C  CA  . ILE B 1 106 ? 45.15431  17.10798  -61.93260 1.000 64.87955  ? 106 ILE B CA  1 
ATOM   4591 C  C   . ILE B 1 106 ? 45.83939  15.74723  -61.93183 1.000 64.39490  ? 106 ILE B C   1 
ATOM   4592 O  O   . ILE B 1 106 ? 46.95611  15.59469  -62.44156 1.000 63.43845  ? 106 ILE B O   1 
ATOM   4593 C  CB  . ILE B 1 106 ? 45.28907  17.80745  -60.56656 1.000 62.40503  ? 106 ILE B CB  1 
ATOM   4594 C  CG1 . ILE B 1 106 ? 44.55407  19.14999  -60.56706 1.000 55.27830  ? 106 ILE B CG1 1 
ATOM   4595 C  CG2 . ILE B 1 106 ? 46.75409  18.00475  -60.20886 1.000 48.95152  ? 106 ILE B CG2 1 
ATOM   4596 C  CD1 . ILE B 1 106 ? 45.14926  20.18020  -61.50032 1.000 52.69530  ? 106 ILE B CD1 1 
ATOM   4597 N  N   . ILE B 1 107 ? 45.17972  14.73800  -61.35881 1.000 67.25648  ? 107 ILE B N   1 
ATOM   4598 C  CA  . ILE B 1 107 ? 45.74595  13.39318  -61.31659 1.000 65.04051  ? 107 ILE B CA  1 
ATOM   4599 C  C   . ILE B 1 107 ? 45.75771  12.76592  -62.70711 1.000 65.23389  ? 107 ILE B C   1 
ATOM   4600 O  O   . ILE B 1 107 ? 46.70115  12.05171  -63.07001 1.000 59.38795  ? 107 ILE B O   1 
ATOM   4601 C  CB  . ILE B 1 107 ? 44.97860  12.52917  -60.29946 1.000 46.72149  ? 107 ILE B CB  1 
ATOM   4602 C  CG1 . ILE B 1 107 ? 45.14283  13.10718  -58.89213 1.000 41.61873  ? 107 ILE B CG1 1 
ATOM   4603 C  CG2 . ILE B 1 107 ? 45.45606  11.08630  -60.34256 1.000 61.84099  ? 107 ILE B CG2 1 
ATOM   4604 C  CD1 . ILE B 1 107 ? 44.51013  12.27040  -57.80907 1.000 54.34577  ? 107 ILE B CD1 1 
ATOM   4605 N  N   . GLN B 1 108 ? 44.71119  13.01509  -63.50431 1.000 67.86859  ? 108 GLN B N   1 
ATOM   4606 C  CA  . GLN B 1 108 ? 44.67428  12.51325  -64.87617 1.000 55.21284  ? 108 GLN B CA  1 
ATOM   4607 C  C   . GLN B 1 108 ? 45.90445  12.93287  -65.66719 1.000 60.37104  ? 108 GLN B C   1 
ATOM   4608 O  O   . GLN B 1 108 ? 46.37093  12.18689  -66.53456 1.000 71.22756  ? 108 GLN B O   1 
ATOM   4609 C  CB  . GLN B 1 108 ? 43.41829  13.01950  -65.59392 1.000 53.86893  ? 108 GLN B CB  1 
ATOM   4610 C  CG  . GLN B 1 108 ? 42.17437  12.16069  -65.42769 1.000 61.82531  ? 108 GLN B CG  1 
ATOM   4611 C  CD  . GLN B 1 108 ? 41.04570  12.60807  -66.34084 1.000 62.02131  ? 108 GLN B CD  1 
ATOM   4612 O  OE1 . GLN B 1 108 ? 40.97822  13.77122  -66.73956 1.000 62.05787  ? 108 GLN B OE1 1 
ATOM   4613 N  NE2 . GLN B 1 108 ? 40.15797  11.68230  -66.68324 1.000 73.42391  ? 108 GLN B NE2 1 
ATOM   4614 N  N   . ASP B 1 109 ? 46.44289  14.11555  -65.38073 1.000 72.07903  ? 109 ASP B N   1 
ATOM   4615 C  CA  . ASP B 1 109 ? 47.56518  14.68441  -66.11449 1.000 68.26559  ? 109 ASP B CA  1 
ATOM   4616 C  C   . ASP B 1 109 ? 48.91475  14.33718  -65.49614 1.000 69.50536  ? 109 ASP B C   1 
ATOM   4617 O  O   . ASP B 1 109 ? 49.94301  14.83035  -65.96882 1.000 66.39474  ? 109 ASP B O   1 
ATOM   4618 C  CB  . ASP B 1 109 ? 47.41847  16.20910  -66.19967 1.000 69.03393  ? 109 ASP B CB  1 
ATOM   4619 C  CG  . ASP B 1 109 ? 46.10356  16.64139  -66.83031 1.000 87.01417  ? 109 ASP B CG  1 
ATOM   4620 O  OD1 . ASP B 1 109 ? 45.36339  15.77159  -67.33724 1.000 92.37451  ? 109 ASP B OD1 1 
ATOM   4621 O  OD2 . ASP B 1 109 ? 45.80936  17.85614  -66.81230 1.000 95.93834  ? 109 ASP B OD2 1 
ATOM   4622 N  N   . MET B 1 110 ? 48.93793  13.50252  -64.46091 1.000 71.61635  ? 110 MET B N   1 
ATOM   4623 C  CA  . MET B 1 110 ? 50.16087  13.25865  -63.70487 1.000 68.65571  ? 110 MET B CA  1 
ATOM   4624 C  C   . MET B 1 110 ? 50.87324  12.01606  -64.20871 1.000 72.72705  ? 110 MET B C   1 
ATOM   4625 O  O   . MET B 1 110 ? 50.23851  10.96094  -64.34798 1.000 82.98584  ? 110 MET B O   1 
ATOM   4626 C  CB  . MET B 1 110 ? 49.83798  13.10065  -62.22171 1.000 65.81194  ? 110 MET B CB  1 
ATOM   4627 C  CG  . MET B 1 110 ? 51.03573  12.78674  -61.34280 1.000 64.74541  ? 110 MET B CG  1 
ATOM   4628 S  SD  . MET B 1 110 ? 50.65429  12.95742  -59.58662 1.000 66.43495  ? 110 MET B SD  1 
ATOM   4629 C  CE  . MET B 1 110 ? 49.19570  11.92723  -59.45058 1.000 68.02012  ? 110 MET B CE  1 
ATOM   4630 N  N   . PRO B 1 111 ? 52.17821  12.08746  -64.48461 1.000 65.62545  ? 111 PRO B N   1 
ATOM   4631 C  CA  . PRO B 1 111 ? 52.93106  10.85953  -64.76948 1.000 74.14329  ? 111 PRO B CA  1 
ATOM   4632 C  C   . PRO B 1 111 ? 53.07063  10.01228  -63.51375 1.000 72.99912  ? 111 PRO B C   1 
ATOM   4633 O  O   . PRO B 1 111 ? 53.84435  10.33986  -62.60810 1.000 71.44968  ? 111 PRO B O   1 
ATOM   4634 C  CB  . PRO B 1 111 ? 54.28637  11.37974  -65.26605 1.000 75.81256  ? 111 PRO B CB  1 
ATOM   4635 C  CG  . PRO B 1 111 ? 54.39552  12.75139  -64.69668 1.000 66.10241  ? 111 PRO B CG  1 
ATOM   4636 C  CD  . PRO B 1 111 ? 53.00153  13.29646  -64.64670 1.000 64.55843  ? 111 PRO B CD  1 
ATOM   4637 N  N   . LYS B 1 112 ? 52.31932  8.91670   -63.45806 1.000 71.44967  ? 112 LYS B N   1 
ATOM   4638 C  CA  . LYS B 1 112 ? 52.16733  8.12306   -62.24736 1.000 64.67160  ? 112 LYS B CA  1 
ATOM   4639 C  C   . LYS B 1 112 ? 53.24254  7.05943   -62.08517 1.000 69.75575  ? 112 LYS B C   1 
ATOM   4640 O  O   . LYS B 1 112 ? 53.22725  6.33444   -61.08367 1.000 65.15809  ? 112 LYS B O   1 
ATOM   4641 C  CB  . LYS B 1 112 ? 50.78587  7.46560   -62.23431 1.000 55.76733  ? 112 LYS B CB  1 
ATOM   4642 C  CG  . LYS B 1 112 ? 49.64987  8.45686   -62.37320 1.000 62.39476  ? 112 LYS B CG  1 
ATOM   4643 C  CD  . LYS B 1 112 ? 48.37089  7.77574   -62.80894 1.000 65.77056  ? 112 LYS B CD  1 
ATOM   4644 C  CE  . LYS B 1 112 ? 47.31018  8.79910   -63.15188 1.000 62.64428  ? 112 LYS B CE  1 
ATOM   4645 N  NZ  . LYS B 1 112 ? 47.72768  9.67460   -64.27808 1.000 52.81147  ? 112 LYS B NZ  1 
ATOM   4646 N  N   . GLY B 1 113 ? 54.15818  6.94733   -63.02396 1.000 71.61793  ? 113 GLY B N   1 
ATOM   4647 C  CA  . GLY B 1 113 ? 55.20556  5.93245   -62.94821 1.000 65.21548  ? 113 GLY B CA  1 
ATOM   4648 C  C   . GLY B 1 113 ? 54.76921  4.63648   -63.61027 1.000 75.05404  ? 113 GLY B C   1 
ATOM   4649 O  O   . GLY B 1 113 ? 54.55408  4.59970   -64.81719 1.000 75.53952  ? 113 GLY B O   1 
ATOM   4650 N  N   . GLY B 1 114 ? 54.62737  3.58685   -62.81141 1.000 74.38817  ? 114 GLY B N   1 
ATOM   4651 C  CA  . GLY B 1 114 ? 54.31723  2.27209   -63.33636 1.000 61.08053  ? 114 GLY B CA  1 
ATOM   4652 C  C   . GLY B 1 114 ? 53.13050  1.63687   -62.64044 1.000 70.15212  ? 114 GLY B C   1 
ATOM   4653 O  O   . GLY B 1 114 ? 52.91078  1.81692   -61.44156 1.000 61.59975  ? 114 GLY B O   1 
ATOM   4654 N  N   . ALA B 1 115 ? 52.35774  0.88237   -63.42243 1.000 73.83794  ? 115 ALA B N   1 
ATOM   4655 C  CA  . ALA B 1 115 ? 51.26342  0.05922   -62.91690 1.000 70.60334  ? 115 ALA B CA  1 
ATOM   4656 C  C   . ALA B 1 115 ? 51.75122  -1.38180  -62.83429 1.000 67.94113  ? 115 ALA B C   1 
ATOM   4657 O  O   . ALA B 1 115 ? 52.06192  -1.99651  -63.86091 1.000 71.51432  ? 115 ALA B O   1 
ATOM   4658 C  CB  . ALA B 1 115 ? 50.03558  0.16705   -63.82113 1.000 58.42747  ? 115 ALA B CB  1 
ATOM   4659 N  N   . LEU B 1 116 ? 51.81342  -1.91643  -61.61951 1.000 64.19698  ? 116 LEU B N   1 
ATOM   4660 C  CA  . LEU B 1 116 ? 52.50332  -3.17360  -61.36729 1.000 61.14058  ? 116 LEU B CA  1 
ATOM   4661 C  C   . LEU B 1 116 ? 51.58313  -4.34722  -61.04831 1.000 68.18053  ? 116 LEU B C   1 
ATOM   4662 O  O   . LEU B 1 116 ? 52.08244  -5.44505  -60.77250 1.000 77.07736  ? 116 LEU B O   1 
ATOM   4663 C  CB  . LEU B 1 116 ? 53.51442  -2.99701  -60.22574 1.000 67.04981  ? 116 LEU B CB  1 
ATOM   4664 C  CG  . LEU B 1 116 ? 54.63489  -1.98821  -60.48940 1.000 61.06197  ? 116 LEU B CG  1 
ATOM   4665 C  CD1 . LEU B 1 116 ? 55.64914  -2.00405  -59.35603 1.000 65.39542  ? 116 LEU B CD1 1 
ATOM   4666 C  CD2 . LEU B 1 116 ? 55.30904  -2.27412  -61.82072 1.000 65.39057  ? 116 LEU B CD2 1 
ATOM   4667 N  N   . HIS B 1 117 ? 50.26340  -4.16267  -61.07084 1.000 64.13392  ? 117 HIS B N   1 
ATOM   4668 C  CA  . HIS B 1 117 ? 49.33350  -5.27449  -60.84240 1.000 63.85164  ? 117 HIS B CA  1 
ATOM   4669 C  C   . HIS B 1 117 ? 48.19850  -5.15273  -61.85622 1.000 68.74375  ? 117 HIS B C   1 
ATOM   4670 O  O   . HIS B 1 117 ? 47.16196  -4.54828  -61.57403 1.000 67.72004  ? 117 HIS B O   1 
ATOM   4671 C  CB  . HIS B 1 117 ? 48.81049  -5.28660  -59.41123 1.000 58.73742  ? 117 HIS B CB  1 
ATOM   4672 C  CG  . HIS B 1 117 ? 48.01723  -6.51060  -59.06802 1.000 59.30630  ? 117 HIS B CG  1 
ATOM   4673 N  ND1 . HIS B 1 117 ? 48.03383  -7.07768  -57.81270 1.000 72.74033  ? 117 HIS B ND1 1 
ATOM   4674 C  CD2 . HIS B 1 117 ? 47.18394  -7.27544  -59.81361 1.000 69.77116  ? 117 HIS B CD2 1 
ATOM   4675 C  CE1 . HIS B 1 117 ? 47.24732  -8.13889  -57.79921 1.000 81.15000  ? 117 HIS B CE1 1 
ATOM   4676 N  NE2 . HIS B 1 117 ? 46.72070  -8.28209  -59.00172 1.000 72.69254  ? 117 HIS B NE2 1 
ATOM   4677 N  N   . LEU B 1 118 ? 48.38860  -5.76615  -63.01957 1.000 69.97425  ? 118 LEU B N   1 
ATOM   4678 C  CA  . LEU B 1 118 ? 47.39985  -5.74801  -64.08388 1.000 65.45967  ? 118 LEU B CA  1 
ATOM   4679 C  C   . LEU B 1 118 ? 47.10399  -7.16872  -64.53327 1.000 63.52317  ? 118 LEU B C   1 
ATOM   4680 O  O   . LEU B 1 118 ? 47.97019  -8.04604  -64.48702 1.000 78.58273  ? 118 LEU B O   1 
ATOM   4681 C  CB  . LEU B 1 118 ? 47.87750  -4.92512  -65.28482 1.000 73.67710  ? 118 LEU B CB  1 
ATOM   4682 C  CG  . LEU B 1 118 ? 47.99917  -3.42080  -65.06637 1.000 70.49160  ? 118 LEU B CG  1 
ATOM   4683 C  CD1 . LEU B 1 118 ? 48.57202  -2.74372  -66.30376 1.000 67.43665  ? 118 LEU B CD1 1 
ATOM   4684 C  CD2 . LEU B 1 118 ? 46.64044  -2.85203  -64.71041 1.000 67.35160  ? 118 LEU B CD2 1 
ATOM   4685 N  N   . HIS B 1 119 ? 45.86676  -7.38633  -64.96744 1.000 53.14203  ? 119 HIS B N   1 
ATOM   4686 C  CA  . HIS B 1 119 ? 45.46316  -8.63597  -65.59529 1.000 63.38789  ? 119 HIS B CA  1 
ATOM   4687 C  C   . HIS B 1 119 ? 45.02207  -8.32258  -67.01509 1.000 68.52195  ? 119 HIS B C   1 
ATOM   4688 O  O   . HIS B 1 119 ? 44.13429  -7.48980  -67.22398 1.000 77.10153  ? 119 HIS B O   1 
ATOM   4689 C  CB  . HIS B 1 119 ? 44.35929  -9.32666  -64.79467 1.000 68.18537  ? 119 HIS B CB  1 
ATOM   4690 C  CG  . HIS B 1 119 ? 44.81301  -9.81520  -63.45422 1.000 74.07519  ? 119 HIS B CG  1 
ATOM   4691 N  ND1 . HIS B 1 119 ? 45.85128  -10.70902 -63.30266 1.000 61.90078  ? 119 HIS B ND1 1 
ATOM   4692 C  CD2 . HIS B 1 119 ? 44.38194  -9.52476  -62.20423 1.000 76.90531  ? 119 HIS B CD2 1 
ATOM   4693 C  CE1 . HIS B 1 119 ? 46.03514  -10.95461 -62.01803 1.000 68.82167  ? 119 HIS B CE1 1 
ATOM   4694 N  NE2 . HIS B 1 119 ? 45.15617  -10.24849 -61.32987 1.000 76.04898  ? 119 HIS B NE2 1 
ATOM   4695 N  N   . ASP B 1 120 ? 45.63888  -9.00535  -67.98112 1.000 67.80201  ? 120 ASP B N   1 
ATOM   4696 C  CA  . ASP B 1 120 ? 45.58463  -8.57119  -69.37424 1.000 58.28257  ? 120 ASP B CA  1 
ATOM   4697 C  C   . ASP B 1 120 ? 44.16272  -8.57636  -69.92348 1.000 66.13209  ? 120 ASP B C   1 
ATOM   4698 O  O   . ASP B 1 120 ? 43.77394  -7.66132  -70.65808 1.000 66.95262  ? 120 ASP B O   1 
ATOM   4699 C  CB  . ASP B 1 120 ? 46.50371  -9.44735  -70.22923 1.000 58.87621  ? 120 ASP B CB  1 
ATOM   4700 C  CG  . ASP B 1 120 ? 46.13255  -10.92541 -70.18418 1.000 61.48380  ? 120 ASP B CG  1 
ATOM   4701 O  OD1 . ASP B 1 120 ? 45.46211  -11.37715 -69.23442 1.000 70.45613  ? 120 ASP B OD1 1 
ATOM   4702 O  OD2 . ASP B 1 120 ? 46.53307  -11.64879 -71.11578 1.000 66.19375  ? 120 ASP B OD2 1 
ATOM   4703 N  N   . THR B 1 121 ? 43.36859  -9.58608  -69.57620 1.000 53.77232  ? 121 THR B N   1 
ATOM   4704 C  CA  . THR B 1 121 ? 42.04392  -9.72001  -70.17077 1.000 58.80473  ? 121 THR B CA  1 
ATOM   4705 C  C   . THR B 1 121 ? 41.04798  -8.67236  -69.67845 1.000 67.70630  ? 121 THR B C   1 
ATOM   4706 O  O   . THR B 1 121 ? 39.87834  -8.73283  -70.07152 1.000 61.33725  ? 121 THR B O   1 
ATOM   4707 C  CB  . THR B 1 121 ? 41.49142  -11.12073 -69.90179 1.000 56.24319  ? 121 THR B CB  1 
ATOM   4708 O  OG1 . THR B 1 121 ? 41.54708  -11.39637 -68.49627 1.000 79.23508  ? 121 THR B OG1 1 
ATOM   4709 C  CG2 . THR B 1 121 ? 42.31152  -12.16539 -70.64722 1.000 60.00736  ? 121 THR B CG2 1 
ATOM   4710 N  N   . ALA B 1 122 ? 41.45719  -7.73434  -68.81920 1.000 69.36713  ? 122 ALA B N   1 
ATOM   4711 C  CA  . ALA B 1 122 ? 40.56166  -6.67514  -68.37062 1.000 66.73793  ? 122 ALA B CA  1 
ATOM   4712 C  C   . ALA B 1 122 ? 41.29222  -5.35292  -68.17797 1.000 62.70114  ? 122 ALA B C   1 
ATOM   4713 O  O   . ALA B 1 122 ? 40.84959  -4.50454  -67.39511 1.000 56.41544  ? 122 ALA B O   1 
ATOM   4714 C  CB  . ALA B 1 122 ? 39.84896  -7.08087  -67.07954 1.000 67.90345  ? 122 ALA B CB  1 
ATOM   4715 N  N   . SER B 1 123 ? 42.41069  -5.16256  -68.87500 1.000 62.58008  ? 123 SER B N   1 
ATOM   4716 C  CA  . SER B 1 123 ? 43.18078  -3.93458  -68.76484 1.000 65.21629  ? 123 SER B CA  1 
ATOM   4717 C  C   . SER B 1 123 ? 42.90900  -2.96153  -69.90784 1.000 67.87833  ? 123 SER B C   1 
ATOM   4718 O  O   . SER B 1 123 ? 43.64820  -1.98549  -70.06301 1.000 67.93831  ? 123 SER B O   1 
ATOM   4719 C  CB  . SER B 1 123 ? 44.67350  -4.25258  -68.67999 1.000 71.88507  ? 123 SER B CB  1 
ATOM   4720 O  OG  . SER B 1 123 ? 44.99498  -4.85995  -67.44079 1.000 63.57720  ? 123 SER B OG  1 
ATOM   4721 N  N   . ALA B 1 124 ? 41.87170  -3.20304  -70.70885 1.000 63.37244  ? 124 ALA B N   1 
ATOM   4722 C  CA  . ALA B 1 124 ? 41.45450  -2.26942  -71.74595 1.000 55.64845  ? 124 ALA B CA  1 
ATOM   4723 C  C   . ALA B 1 124 ? 39.93230  -2.21591  -71.77940 1.000 56.51710  ? 124 ALA B C   1 
ATOM   4724 O  O   . ALA B 1 124 ? 39.24680  -3.03986  -71.17142 1.000 55.17899  ? 124 ALA B O   1 
ATOM   4725 C  CB  . ALA B 1 124 ? 42.02103  -2.64925  -73.11828 1.000 51.90555  ? 124 ALA B CB  1 
ATOM   4726 N  N   . ARG B 1 125 ? 39.40229  -1.23384  -72.50221 1.000 73.52371  ? 125 ARG B N   1 
ATOM   4727 C  CA  . ARG B 1 125 ? 37.98465  -0.91157  -72.39925 1.000 78.42308  ? 125 ARG B CA  1 
ATOM   4728 C  C   . ARG B 1 125 ? 37.10432  -2.00602  -72.98790 1.000 64.71258  ? 125 ARG B C   1 
ATOM   4729 O  O   . ARG B 1 125 ? 37.46932  -2.67357  -73.96039 1.000 68.41659  ? 125 ARG B O   1 
ATOM   4730 C  CB  . ARG B 1 125 ? 37.67392  0.40541   -73.11146 1.000 63.15422  ? 125 ARG B CB  1 
ATOM   4731 C  CG  . ARG B 1 125 ? 38.08200  1.65597   -72.37190 1.000 76.77619  ? 125 ARG B CG  1 
ATOM   4732 C  CD  . ARG B 1 125 ? 37.22534  2.80567   -72.87149 1.000 104.12031 ? 125 ARG B CD  1 
ATOM   4733 N  NE  . ARG B 1 125 ? 37.58273  4.08196   -72.26879 1.000 114.11531 ? 125 ARG B NE  1 
ATOM   4734 C  CZ  . ARG B 1 125 ? 36.88755  5.20068   -72.42229 1.000 114.35599 ? 125 ARG B CZ  1 
ATOM   4735 N  NH1 . ARG B 1 125 ? 35.77889  5.23301   -73.14431 1.000 104.29159 ? 125 ARG B NH1 1 
ATOM   4736 N  NH2 . ARG B 1 125 ? 37.31409  6.31442   -71.83438 1.000 126.71696 ? 125 ARG B NH2 1 
ATOM   4737 N  N   . ILE B 1 126 ? 35.93358  -2.18898  -72.37442 1.000 59.71928  ? 126 ILE B N   1 
ATOM   4738 C  CA  . ILE B 1 126 ? 34.87172  -2.97813  -72.98901 1.000 68.13150  ? 126 ILE B CA  1 
ATOM   4739 C  C   . ILE B 1 126 ? 34.40274  -2.31450  -74.27655 1.000 65.31591  ? 126 ILE B C   1 
ATOM   4740 O  O   . ILE B 1 126 ? 33.96170  -2.99205  -75.21486 1.000 64.70041  ? 126 ILE B O   1 
ATOM   4741 C  CB  . ILE B 1 126 ? 33.70289  -3.16458  -71.99845 1.000 54.61927  ? 126 ILE B CB  1 
ATOM   4742 C  CG1 . ILE B 1 126 ? 34.20440  -3.73236  -70.66817 1.000 53.51538  ? 126 ILE B CG1 1 
ATOM   4743 C  CG2 . ILE B 1 126 ? 32.63845  -4.07035  -72.58529 1.000 45.85062  ? 126 ILE B CG2 1 
ATOM   4744 C  CD1 . ILE B 1 126 ? 33.10957  -3.91145  -69.63184 1.000 60.43038  ? 126 ILE B CD1 1 
ATOM   4745 N  N   . ASP B 1 127 ? 34.48206  -0.98145  -74.33777 1.000 66.88511  ? 127 ASP B N   1 
ATOM   4746 C  CA  . ASP B 1 127 ? 34.03306  -0.24482  -75.51518 1.000 78.52313  ? 127 ASP B CA  1 
ATOM   4747 C  C   . ASP B 1 127 ? 34.81671  -0.63889  -76.75922 1.000 81.24414  ? 127 ASP B C   1 
ATOM   4748 O  O   . ASP B 1 127 ? 34.25952  -0.66132  -77.86294 1.000 80.03140  ? 127 ASP B O   1 
ATOM   4749 C  CB  . ASP B 1 127 ? 34.15916  1.26111   -75.26817 1.000 74.91144  ? 127 ASP B CB  1 
ATOM   4750 C  CG  . ASP B 1 127 ? 33.36670  1.72864   -74.05896 1.000 83.46246  ? 127 ASP B CG  1 
ATOM   4751 O  OD1 . ASP B 1 127 ? 33.63727  1.25362   -72.93440 1.000 95.08249  ? 127 ASP B OD1 1 
ATOM   4752 O  OD2 . ASP B 1 127 ? 32.47634  2.58568   -74.23237 1.000 90.98641  ? 127 ASP B OD2 1 
ATOM   4753 N  N   . TRP B 1 128 ? 36.10404  -0.95250  -76.60295 1.000 73.27104  ? 128 TRP B N   1 
ATOM   4754 C  CA  . TRP B 1 128 ? 36.89830  -1.40630  -77.73865 1.000 67.68383  ? 128 TRP B CA  1 
ATOM   4755 C  C   . TRP B 1 128 ? 36.38728  -2.73460  -78.27990 1.000 68.21043  ? 128 TRP B C   1 
ATOM   4756 O  O   . TRP B 1 128 ? 36.46648  -2.98329  -79.48840 1.000 64.77713  ? 128 TRP B O   1 
ATOM   4757 C  CB  . TRP B 1 128 ? 38.36758  -1.52464  -77.33312 1.000 63.61920  ? 128 TRP B CB  1 
ATOM   4758 C  CG  . TRP B 1 128 ? 39.28032  -1.90178  -78.45823 1.000 64.49090  ? 128 TRP B CG  1 
ATOM   4759 C  CD1 . TRP B 1 128 ? 39.85436  -1.05870  -79.36374 1.000 70.93944  ? 128 TRP B CD1 1 
ATOM   4760 C  CD2 . TRP B 1 128 ? 39.73252  -3.21918  -78.79430 1.000 77.43462  ? 128 TRP B CD2 1 
ATOM   4761 N  NE1 . TRP B 1 128 ? 40.63277  -1.76848  -80.24535 1.000 81.80667  ? 128 TRP B NE1 1 
ATOM   4762 C  CE2 . TRP B 1 128 ? 40.57525  -3.09730  -79.91729 1.000 77.95516  ? 128 TRP B CE2 1 
ATOM   4763 C  CE3 . TRP B 1 128 ? 39.50556  -4.48939  -78.25618 1.000 64.89033  ? 128 TRP B CE3 1 
ATOM   4764 C  CZ2 . TRP B 1 128 ? 41.19069  -4.19615  -80.51098 1.000 65.95044  ? 128 TRP B CZ2 1 
ATOM   4765 C  CZ3 . TRP B 1 128 ? 40.11783  -5.57878  -78.84687 1.000 63.04356  ? 128 TRP B CZ3 1 
ATOM   4766 C  CH2 . TRP B 1 128 ? 40.95043  -5.42524  -79.96265 1.000 68.18640  ? 128 TRP B CH2 1 
ATOM   4767 N  N   . ILE B 1 129 ? 35.87322  -3.59871  -77.40494 1.000 70.33463  ? 129 ILE B N   1 
ATOM   4768 C  CA  . ILE B 1 129 ? 35.35087  -4.88545  -77.84720 1.000 68.13253  ? 129 ILE B CA  1 
ATOM   4769 C  C   . ILE B 1 129 ? 34.04672  -4.70460  -78.61516 1.000 67.69629  ? 129 ILE B C   1 
ATOM   4770 O  O   . ILE B 1 129 ? 33.78078  -5.41844  -79.58729 1.000 79.30371  ? 129 ILE B O   1 
ATOM   4771 C  CB  . ILE B 1 129 ? 35.18488  -5.82639  -76.63979 1.000 58.90154  ? 129 ILE B CB  1 
ATOM   4772 C  CG1 . ILE B 1 129 ? 36.54509  -6.05075  -75.97081 1.000 53.12437  ? 129 ILE B CG1 1 
ATOM   4773 C  CG2 . ILE B 1 129 ? 34.56216  -7.15287  -77.06369 1.000 55.68429  ? 129 ILE B CG2 1 
ATOM   4774 C  CD1 . ILE B 1 129 ? 36.48505  -6.87668  -74.70619 1.000 66.07122  ? 129 ILE B CD1 1 
ATOM   4775 N  N   . VAL B 1 130 ? 33.21494  -3.75018  -78.19871 1.000 66.72971  ? 130 VAL B N   1 
ATOM   4776 C  CA  . VAL B 1 130 ? 31.93337  -3.55551  -78.86766 1.000 70.98350  ? 130 VAL B CA  1 
ATOM   4777 C  C   . VAL B 1 130 ? 32.10750  -2.82018  -80.19620 1.000 79.68440  ? 130 VAL B C   1 
ATOM   4778 O  O   . VAL B 1 130 ? 31.45272  -3.15277  -81.18847 1.000 79.56108  ? 130 VAL B O   1 
ATOM   4779 C  CB  . VAL B 1 130 ? 30.95288  -2.82636  -77.93027 1.000 68.36990  ? 130 VAL B CB  1 
ATOM   4780 C  CG1 . VAL B 1 130 ? 29.63278  -2.58200  -78.63892 1.000 55.28954  ? 130 VAL B CG1 1 
ATOM   4781 C  CG2 . VAL B 1 130 ? 30.73370  -3.63884  -76.65968 1.000 77.74493  ? 130 VAL B CG2 1 
ATOM   4782 N  N   . SER B 1 131 ? 32.98169  -1.81542  -80.24966 1.000 81.82858  ? 131 SER B N   1 
ATOM   4783 C  CA  . SER B 1 131 ? 33.08449  -0.99496  -81.45217 1.000 79.47846  ? 131 SER B CA  1 
ATOM   4784 C  C   . SER B 1 131 ? 34.03353  -1.57201  -82.49677 1.000 77.74219  ? 131 SER B C   1 
ATOM   4785 O  O   . SER B 1 131 ? 33.79581  -1.38978  -83.69849 1.000 80.23784  ? 131 SER B O   1 
ATOM   4786 C  CB  . SER B 1 131 ? 33.51708  0.42920   -81.09134 1.000 75.64530  ? 131 SER B CB  1 
ATOM   4787 O  OG  . SER B 1 131 ? 34.78531  0.44125   -80.46060 1.000 91.60145  ? 131 SER B OG  1 
ATOM   4788 N  N   . ASN B 1 132 ? 35.10310  -2.25128  -82.07256 1.000 67.61332  ? 132 ASN B N   1 
ATOM   4789 C  CA  . ASN B 1 132 ? 36.01030  -2.93405  -82.99113 1.000 59.83374  ? 132 ASN B CA  1 
ATOM   4790 C  C   . ASN B 1 132 ? 35.69890  -4.42516  -83.09478 1.000 83.80784  ? 132 ASN B C   1 
ATOM   4791 O  O   . ASN B 1 132 ? 35.41209  -4.92493  -84.18654 1.000 91.55848  ? 132 ASN B O   1 
ATOM   4792 C  CB  . ASN B 1 132 ? 37.47305  -2.70975  -82.55006 1.000 54.94388  ? 132 ASN B CB  1 
ATOM   4793 C  CG  . ASN B 1 132 ? 38.46903  -3.71018  -83.21353 1.000 76.62331  ? 132 ASN B CG  1 
ATOM   4794 O  OD1 . ASN B 1 132 ? 38.38139  -4.89623  -82.90766 1.000 94.47405  ? 132 ASN B OD1 1 
ATOM   4795 N  ND2 . ASN B 1 132 ? 39.41272  -3.28115  -84.10053 1.000 86.98785  ? 132 ASN B ND2 1 
ATOM   4796 N  N   . ALA B 1 133 ? 35.75097  -5.14776  -81.96848 1.000 88.28890  ? 133 ALA B N   1 
ATOM   4797 C  CA  . ALA B 1 133 ? 35.78945  -6.60865  -82.02230 1.000 71.44981  ? 133 ALA B CA  1 
ATOM   4798 C  C   . ALA B 1 133 ? 34.48375  -7.19611  -82.54823 1.000 67.82484  ? 133 ALA B C   1 
ATOM   4799 O  O   . ALA B 1 133 ? 34.49362  -8.02169  -83.46970 1.000 65.94304  ? 133 ALA B O   1 
ATOM   4800 C  CB  . ALA B 1 133 ? 36.12007  -7.18094  -80.64443 1.000 63.36242  ? 133 ALA B CB  1 
ATOM   4801 N  N   . THR B 1 134 ? 33.34768  -6.78530  -81.98454 1.000 61.86877  ? 134 THR B N   1 
ATOM   4802 C  CA  . THR B 1 134 ? 32.06465  -7.32376  -82.42355 1.000 68.28295  ? 134 THR B CA  1 
ATOM   4803 C  C   . THR B 1 134 ? 31.61018  -6.73917  -83.75280 1.000 81.13446  ? 134 THR B C   1 
ATOM   4804 O  O   . THR B 1 134 ? 30.48750  -7.01966  -84.18821 1.000 81.24734  ? 134 THR B O   1 
ATOM   4805 C  CB  . THR B 1 134 ? 30.98410  -7.09367  -81.36207 1.000 65.52243  ? 134 THR B CB  1 
ATOM   4806 O  OG1 . THR B 1 134 ? 30.67570  -5.69924  -81.28221 1.000 73.69991  ? 134 THR B OG1 1 
ATOM   4807 C  CG2 . THR B 1 134 ? 31.45633  -7.58403  -80.00444 1.000 74.48684  ? 134 THR B CG2 1 
ATOM   4808 N  N   . TYR B 1 135 ? 32.45124  -5.92852  -84.39319 1.000 75.50431  ? 135 TYR B N   1 
ATOM   4809 C  CA  . TYR B 1 135 ? 32.24042  -5.49760  -85.76578 1.000 73.81384  ? 135 TYR B CA  1 
ATOM   4810 C  C   . TYR B 1 135 ? 33.14667  -6.22337  -86.74775 1.000 84.99134  ? 135 TYR B C   1 
ATOM   4811 O  O   . TYR B 1 135 ? 33.03344  -6.00079  -87.95789 1.000 99.98123  ? 135 TYR B O   1 
ATOM   4812 C  CB  . TYR B 1 135 ? 32.44305  -3.98414  -85.88787 1.000 63.98272  ? 135 TYR B CB  1 
ATOM   4813 C  CG  . TYR B 1 135 ? 31.19374  -3.18963  -85.58811 1.000 73.76573  ? 135 TYR B CG  1 
ATOM   4814 C  CD1 . TYR B 1 135 ? 30.15693  -3.12527  -86.50846 1.000 77.60979  ? 135 TYR B CD1 1 
ATOM   4815 C  CD2 . TYR B 1 135 ? 31.04731  -2.50991  -84.38724 1.000 75.65722  ? 135 TYR B CD2 1 
ATOM   4816 C  CE1 . TYR B 1 135 ? 29.01025  -2.40520  -86.24232 1.000 80.51605  ? 135 TYR B CE1 1 
ATOM   4817 C  CE2 . TYR B 1 135 ? 29.90472  -1.78512  -84.11242 1.000 77.79636  ? 135 TYR B CE2 1 
ATOM   4818 C  CZ  . TYR B 1 135 ? 28.88973  -1.73697  -85.04411 1.000 81.66137  ? 135 TYR B CZ  1 
ATOM   4819 O  OH  . TYR B 1 135 ? 27.74935  -1.01752  -84.78033 1.000 83.79193  ? 135 TYR B OH  1 
ATOM   4820 N  N   . ARG B 1 136 ? 34.04206  -7.07919  -86.26291 1.000 68.99512  ? 136 ARG B N   1 
ATOM   4821 C  CA  . ARG B 1 136 ? 34.82224  -7.93121  -87.14317 1.000 69.68913  ? 136 ARG B CA  1 
ATOM   4822 C  C   . ARG B 1 136 ? 33.95692  -9.07380  -87.66929 1.000 73.46019  ? 136 ARG B C   1 
ATOM   4823 O  O   . ARG B 1 136 ? 32.85272  -9.33138  -87.18094 1.000 71.44992  ? 136 ARG B O   1 
ATOM   4824 C  CB  . ARG B 1 136 ? 36.04564  -8.48613  -86.41721 1.000 66.53333  ? 136 ARG B CB  1 
ATOM   4825 C  CG  . ARG B 1 136 ? 36.92691  -7.43191  -85.78589 1.000 62.01816  ? 136 ARG B CG  1 
ATOM   4826 C  CD  . ARG B 1 136 ? 38.33698  -7.95331  -85.59759 1.000 62.61135  ? 136 ARG B CD  1 
ATOM   4827 N  NE  . ARG B 1 136 ? 39.15961  -7.01819  -84.84332 1.000 60.40540  ? 136 ARG B NE  1 
ATOM   4828 C  CZ  . ARG B 1 136 ? 40.47847  -7.09636  -84.73977 1.000 67.75331  ? 136 ARG B CZ  1 
ATOM   4829 N  NH1 . ARG B 1 136 ? 41.16471  -8.04890  -85.35021 1.000 70.91220  ? 136 ARG B NH1 1 
ATOM   4830 N  NH2 . ARG B 1 136 ? 41.12472  -6.19417  -84.00812 1.000 52.56849  ? 136 ARG B NH2 1 
ATOM   4831 N  N   . ASP B 1 137 ? 34.47047  -9.76260  -88.68317 1.000 83.68699  ? 137 ASP B N   1 
ATOM   4832 C  CA  . ASP B 1 137 ? 33.76454  -10.89646 -89.25532 1.000 80.59824  ? 137 ASP B CA  1 
ATOM   4833 C  C   . ASP B 1 137 ? 34.04405  -12.16461 -88.45375 1.000 75.11886  ? 137 ASP B C   1 
ATOM   4834 O  O   . ASP B 1 137 ? 35.03280  -12.26024 -87.72017 1.000 73.36827  ? 137 ASP B O   1 
ATOM   4835 C  CB  . ASP B 1 137 ? 34.15282  -11.09016 -90.71964 1.000 77.59678  ? 137 ASP B CB  1 
ATOM   4836 C  CG  . ASP B 1 137 ? 33.55141  -10.03262 -91.61996 1.000 84.70328  ? 137 ASP B CG  1 
ATOM   4837 O  OD1 . ASP B 1 137 ? 32.88974  -9.11461  -91.09156 1.000 87.44986  ? 137 ASP B OD1 1 
ATOM   4838 O  OD2 . ASP B 1 137 ? 33.72964  -10.11869 -92.85166 1.000 91.85944  ? 137 ASP B OD2 1 
ATOM   4839 N  N   . HIS B 1 138 ? 33.13166  -13.13353 -88.59081 1.000 86.36566  ? 138 HIS B N   1 
ATOM   4840 C  CA  . HIS B 1 138 ? 33.19559  -14.42815 -87.91057 1.000 90.70593  ? 138 HIS B CA  1 
ATOM   4841 C  C   . HIS B 1 138 ? 32.94843  -14.31040 -86.40844 1.000 85.18888  ? 138 HIS B C   1 
ATOM   4842 O  O   . HIS B 1 138 ? 33.48478  -15.09551 -85.62418 1.000 89.77998  ? 138 HIS B O   1 
ATOM   4843 C  CB  . HIS B 1 138 ? 34.52614  -15.14819 -88.16778 1.000 79.67569  ? 138 HIS B CB  1 
ATOM   4844 C  CG  . HIS B 1 138 ? 34.81123  -15.39704 -89.61562 1.000 84.71150  ? 138 HIS B CG  1 
ATOM   4845 N  ND1 . HIS B 1 138 ? 36.09018  -15.41748 -90.12888 1.000 78.62806  ? 138 HIS B ND1 1 
ATOM   4846 C  CD2 . HIS B 1 138 ? 33.98347  -15.64366 -90.65830 1.000 86.51369  ? 138 HIS B CD2 1 
ATOM   4847 C  CE1 . HIS B 1 138 ? 36.03782  -15.65967 -91.42647 1.000 81.00501  ? 138 HIS B CE1 1 
ATOM   4848 N  NE2 . HIS B 1 138 ? 34.77105  -15.80167 -91.77270 1.000 90.88270  ? 138 HIS B NE2 1 
ATOM   4849 N  N   . VAL B 1 139 ? 32.13804  -13.34281 -85.98905 1.000 72.64227  ? 139 VAL B N   1 
ATOM   4850 C  CA  . VAL B 1 139 ? 31.80541  -13.14590 -84.58191 1.000 67.85367  ? 139 VAL B CA  1 
ATOM   4851 C  C   . VAL B 1 139 ? 30.34592  -13.52890 -84.37749 1.000 72.29956  ? 139 VAL B C   1 
ATOM   4852 O  O   . VAL B 1 139 ? 29.44882  -12.94558 -84.99898 1.000 65.14927  ? 139 VAL B O   1 
ATOM   4853 C  CB  . VAL B 1 139 ? 32.06691  -11.70061 -84.13066 1.000 62.44323  ? 139 VAL B CB  1 
ATOM   4854 C  CG1 . VAL B 1 139 ? 31.61773  -11.50681 -82.69310 1.000 60.68142  ? 139 VAL B CG1 1 
ATOM   4855 C  CG2 . VAL B 1 139 ? 33.54164  -11.36097 -84.27424 1.000 67.50404  ? 139 VAL B CG2 1 
ATOM   4856 N  N   . TYR B 1 140 ? 30.11131  -14.50530 -83.50574 1.000 75.49880  ? 140 TYR B N   1 
ATOM   4857 C  CA  . TYR B 1 140 ? 28.77572  -14.94787 -83.13708 1.000 73.01603  ? 140 TYR B CA  1 
ATOM   4858 C  C   . TYR B 1 140 ? 28.47968  -14.55510 -81.69441 1.000 69.82221  ? 140 TYR B C   1 
ATOM   4859 O  O   . TYR B 1 140 ? 29.38686  -14.34623 -80.88413 1.000 71.00553  ? 140 TYR B O   1 
ATOM   4860 C  CB  . TYR B 1 140 ? 28.62545  -16.46640 -83.30223 1.000 82.62021  ? 140 TYR B CB  1 
ATOM   4861 C  CG  . TYR B 1 140 ? 28.81450  -16.97882 -84.71474 1.000 83.76813  ? 140 TYR B CG  1 
ATOM   4862 C  CD1 . TYR B 1 140 ? 30.08428  -17.22387 -85.22124 1.000 91.03419  ? 140 TYR B CD1 1 
ATOM   4863 C  CD2 . TYR B 1 140 ? 27.72200  -17.23864 -85.53440 1.000 78.29033  ? 140 TYR B CD2 1 
ATOM   4864 C  CE1 . TYR B 1 140 ? 30.26388  -17.69881 -86.50701 1.000 98.77915  ? 140 TYR B CE1 1 
ATOM   4865 C  CE2 . TYR B 1 140 ? 27.89163  -17.71651 -86.82297 1.000 92.11533  ? 140 TYR B CE2 1 
ATOM   4866 C  CZ  . TYR B 1 140 ? 29.16527  -17.94336 -87.30330 1.000 100.39506 ? 140 TYR B CZ  1 
ATOM   4867 O  OH  . TYR B 1 140 ? 29.34462  -18.41733 -88.58301 1.000 93.89214  ? 140 TYR B OH  1 
ATOM   4868 N  N   . MET B 1 141 ? 27.18857  -14.46002 -81.38131 1.000 77.09628  ? 141 MET B N   1 
ATOM   4869 C  CA  . MET B 1 141 ? 26.72791  -14.09267 -80.05018 1.000 73.70766  ? 141 MET B CA  1 
ATOM   4870 C  C   . MET B 1 141 ? 25.57952  -15.00486 -79.64844 1.000 82.58818  ? 141 MET B C   1 
ATOM   4871 O  O   . MET B 1 141 ? 24.92621  -15.62050 -80.49367 1.000 91.74565  ? 141 MET B O   1 
ATOM   4872 C  CB  . MET B 1 141 ? 26.26904  -12.63217 -79.98621 1.000 59.09741  ? 141 MET B CB  1 
ATOM   4873 C  CG  . MET B 1 141 ? 25.09316  -12.32907 -80.89696 1.000 72.98606  ? 141 MET B CG  1 
ATOM   4874 S  SD  . MET B 1 141 ? 24.43286  -10.67297 -80.65935 1.000 74.62087  ? 141 MET B SD  1 
ATOM   4875 C  CE  . MET B 1 141 ? 23.79003  -10.80531 -78.99426 1.000 55.10405  ? 141 MET B CE  1 
ATOM   4876 N  N   . CYS B 1 142 ? 25.33432  -15.08240 -78.34234 1.000 82.01508  ? 142 CYS B N   1 
ATOM   4877 C  CA  . CYS B 1 142 ? 24.24934  -15.91320 -77.84283 1.000 82.44419  ? 142 CYS B CA  1 
ATOM   4878 C  C   . CYS B 1 142 ? 23.92478  -15.51716 -76.41014 1.000 85.01095  ? 142 CYS B C   1 
ATOM   4879 O  O   . CYS B 1 142 ? 24.77226  -14.98204 -75.69155 1.000 86.73591  ? 142 CYS B O   1 
ATOM   4880 C  CB  . CYS B 1 142 ? 24.61335  -17.39793 -77.91816 1.000 87.79574  ? 142 CYS B CB  1 
ATOM   4881 S  SG  . CYS B 1 142 ? 25.38233  -18.05479 -76.43152 1.000 99.90375  ? 142 CYS B SG  1 
ATOM   4882 N  N   . MET B 1 143 ? 22.68571  -15.78902 -76.00818 1.000 85.66672  ? 143 MET B N   1 
ATOM   4883 C  CA  . MET B 1 143 ? 22.22574  -15.56072 -74.64305 1.000 78.92143  ? 143 MET B CA  1 
ATOM   4884 C  C   . MET B 1 143 ? 22.27227  -16.89151 -73.90315 1.000 76.92966  ? 143 MET B C   1 
ATOM   4885 O  O   . MET B 1 143 ? 21.50149  -17.80579 -74.21195 1.000 83.48849  ? 143 MET B O   1 
ATOM   4886 C  CB  . MET B 1 143 ? 20.81293  -14.98167 -74.63230 1.000 58.25110  ? 143 MET B CB  1 
ATOM   4887 C  CG  . MET B 1 143 ? 20.68062  -13.63773 -75.32078 1.000 72.34879  ? 143 MET B CG  1 
ATOM   4888 S  SD  . MET B 1 143 ? 21.44783  -12.30761 -74.37940 1.000 80.35164  ? 143 MET B SD  1 
ATOM   4889 C  CE  . MET B 1 143 ? 20.52967  -12.40263 -72.84336 1.000 79.99417  ? 143 MET B CE  1 
ATOM   4890 N  N   . ASP B 1 144 ? 23.16672  -16.99964 -72.92381 1.000 74.73183  ? 144 ASP B N   1 
ATOM   4891 C  CA  . ASP B 1 144 ? 23.29370  -18.24593 -72.18602 1.000 75.22926  ? 144 ASP B CA  1 
ATOM   4892 C  C   . ASP B 1 144 ? 22.09352  -18.42447 -71.25385 1.000 73.80175  ? 144 ASP B C   1 
ATOM   4893 O  O   . ASP B 1 144 ? 21.18424  -17.59148 -71.19203 1.000 68.89948  ? 144 ASP B O   1 
ATOM   4894 C  CB  . ASP B 1 144 ? 24.62754  -18.29326 -71.43625 1.000 73.50030  ? 144 ASP B CB  1 
ATOM   4895 C  CG  . ASP B 1 144 ? 24.73760  -17.25024 -70.33288 1.000 76.61743  ? 144 ASP B CG  1 
ATOM   4896 O  OD1 . ASP B 1 144 ? 23.79517  -16.45846 -70.13303 1.000 80.87470  ? 144 ASP B OD1 1 
ATOM   4897 O  OD2 . ASP B 1 144 ? 25.78638  -17.22693 -69.65545 1.000 76.72482  ? 144 ASP B OD2 1 
ATOM   4898 N  N   . GLN B 1 145 ? 22.09509  -19.53184 -70.51139 1.000 77.08195  ? 145 GLN B N   1 
ATOM   4899 C  CA  . GLN B 1 145 ? 20.93896  -19.89668 -69.70097 1.000 79.96988  ? 145 GLN B CA  1 
ATOM   4900 C  C   . GLN B 1 145 ? 20.72565  -18.97435 -68.50706 1.000 86.58367  ? 145 GLN B C   1 
ATOM   4901 O  O   . GLN B 1 145 ? 19.68059  -19.07080 -67.85443 1.000 92.59909  ? 145 GLN B O   1 
ATOM   4902 C  CB  . GLN B 1 145 ? 21.07578  -21.34675 -69.23394 1.000 80.15111  ? 145 GLN B CB  1 
ATOM   4903 C  CG  . GLN B 1 145 ? 21.19610  -22.33037 -70.38832 1.000 83.23267  ? 145 GLN B CG  1 
ATOM   4904 C  CD  . GLN B 1 145 ? 20.86069  -23.75528 -69.99719 1.000 77.67106  ? 145 GLN B CD  1 
ATOM   4905 O  OE1 . GLN B 1 145 ? 21.09082  -24.17452 -68.86323 1.000 92.09521  ? 145 GLN B OE1 1 
ATOM   4906 N  NE2 . GLN B 1 145 ? 20.31018  -24.50983 -70.94141 1.000 59.89394  ? 145 GLN B NE2 1 
ATOM   4907 N  N   . ASP B 1 146 ? 21.67697  -18.09285 -68.20558 1.000 83.18316  ? 146 ASP B N   1 
ATOM   4908 C  CA  . ASP B 1 146 ? 21.55063  -17.14031 -67.11156 1.000 75.14053  ? 146 ASP B CA  1 
ATOM   4909 C  C   . ASP B 1 146 ? 21.13712  -15.74877 -67.58152 1.000 75.98473  ? 146 ASP B C   1 
ATOM   4910 O  O   . ASP B 1 146 ? 21.17353  -14.80568 -66.78429 1.000 85.92443  ? 146 ASP B O   1 
ATOM   4911 C  CB  . ASP B 1 146 ? 22.86751  -17.05812 -66.33661 1.000 77.40561  ? 146 ASP B CB  1 
ATOM   4912 C  CG  . ASP B 1 146 ? 23.28735  -18.39416 -65.75582 1.000 82.15735  ? 146 ASP B CG  1 
ATOM   4913 O  OD1 . ASP B 1 146 ? 22.47994  -19.01121 -65.02978 1.000 87.22539  ? 146 ASP B OD1 1 
ATOM   4914 O  OD2 . ASP B 1 146 ? 24.42536  -18.82960 -66.03160 1.000 73.96800  ? 146 ASP B OD2 1 
ATOM   4915 N  N   . ASN B 1 147 ? 20.75034  -15.60307 -68.85439 1.000 67.27978  ? 147 ASN B N   1 
ATOM   4916 C  CA  . ASN B 1 147 ? 20.37678  -14.31315 -69.44996 1.000 75.34990  ? 147 ASN B CA  1 
ATOM   4917 C  C   . ASN B 1 147 ? 21.56742  -13.35487 -69.51519 1.000 81.25393  ? 147 ASN B C   1 
ATOM   4918 O  O   . ASN B 1 147 ? 21.42936  -12.15464 -69.27690 1.000 88.75483  ? 147 ASN B O   1 
ATOM   4919 C  CB  . ASN B 1 147 ? 19.19861  -13.66204 -68.71645 1.000 79.78811  ? 147 ASN B CB  1 
ATOM   4920 C  CG  . ASN B 1 147 ? 17.86587  -13.95508 -69.37685 1.000 88.26952  ? 147 ASN B CG  1 
ATOM   4921 O  OD1 . ASN B 1 147 ? 17.50247  -13.32752 -70.37216 1.000 82.58341  ? 147 ASN B OD1 1 
ATOM   4922 N  ND2 . ASN B 1 147 ? 17.12642  -14.90788 -68.82178 1.000 94.47843  ? 147 ASN B ND2 1 
ATOM   4923 N  N   . PHE B 1 148 ? 22.74169  -13.88903 -69.84046 1.000 71.09166  ? 148 PHE B N   1 
ATOM   4924 C  CA  . PHE B 1 148 ? 23.94330  -13.10136 -70.07000 1.000 72.05681  ? 148 PHE B CA  1 
ATOM   4925 C  C   . PHE B 1 148 ? 24.43072  -13.32665 -71.49578 1.000 79.76767  ? 148 PHE B C   1 
ATOM   4926 O  O   . PHE B 1 148 ? 24.25230  -14.40699 -72.06573 1.000 81.03874  ? 148 PHE B O   1 
ATOM   4927 C  CB  . PHE B 1 148 ? 25.05457  -13.46341 -69.07453 1.000 74.44477  ? 148 PHE B CB  1 
ATOM   4928 C  CG  . PHE B 1 148 ? 24.79946  -12.97788 -67.67600 1.000 74.08955  ? 148 PHE B CG  1 
ATOM   4929 C  CD1 . PHE B 1 148 ? 24.02079  -13.71612 -66.80300 1.000 71.05338  ? 148 PHE B CD1 1 
ATOM   4930 C  CD2 . PHE B 1 148 ? 25.34844  -11.78759 -67.23194 1.000 80.18628  ? 148 PHE B CD2 1 
ATOM   4931 C  CE1 . PHE B 1 148 ? 23.78604  -13.27312 -65.51522 1.000 72.50170  ? 148 PHE B CE1 1 
ATOM   4932 C  CE2 . PHE B 1 148 ? 25.11864  -11.33970 -65.94583 1.000 70.30861  ? 148 PHE B CE2 1 
ATOM   4933 C  CZ  . PHE B 1 148 ? 24.33720  -12.08347 -65.08552 1.000 72.56863  ? 148 PHE B CZ  1 
ATOM   4934 N  N   . VAL B 1 149 ? 25.04240  -12.29602 -72.07115 1.000 75.51281  ? 149 VAL B N   1 
ATOM   4935 C  CA  . VAL B 1 149 ? 25.49931  -12.35056 -73.45540 1.000 67.52176  ? 149 VAL B CA  1 
ATOM   4936 C  C   . VAL B 1 149 ? 26.86638  -13.01225 -73.51574 1.000 65.05475  ? 149 VAL B C   1 
ATOM   4937 O  O   . VAL B 1 149 ? 27.71615  -12.80046 -72.64639 1.000 67.16340  ? 149 VAL B O   1 
ATOM   4938 C  CB  . VAL B 1 149 ? 25.54369  -10.93905 -74.06402 1.000 70.41357  ? 149 VAL B CB  1 
ATOM   4939 C  CG1 . VAL B 1 149 ? 25.69780  -11.01171 -75.57636 1.000 69.73938  ? 149 VAL B CG1 1 
ATOM   4940 C  CG2 . VAL B 1 149 ? 24.30485  -10.16715 -73.68048 1.000 83.87668  ? 149 VAL B CG2 1 
ATOM   4941 N  N   . ARG B 1 150 ? 27.09008  -13.81225 -74.55219 1.000 62.14761  ? 150 ARG B N   1 
ATOM   4942 C  CA  . ARG B 1 150 ? 28.38057  -14.44511 -74.77902 1.000 62.22758  ? 150 ARG B CA  1 
ATOM   4943 C  C   . ARG B 1 150 ? 28.82410  -14.18578 -76.20978 1.000 68.82823  ? 150 ARG B C   1 
ATOM   4944 O  O   . ARG B 1 150 ? 28.00163  -14.15436 -77.12905 1.000 82.97595  ? 150 ARG B O   1 
ATOM   4945 C  CB  . ARG B 1 150 ? 28.32518  -15.95024 -74.50496 1.000 80.71463  ? 150 ARG B CB  1 
ATOM   4946 C  CG  . ARG B 1 150 ? 28.21884  -16.30377 -73.03094 1.000 84.51093  ? 150 ARG B CG  1 
ATOM   4947 C  CD  . ARG B 1 150 ? 28.54194  -17.76818 -72.79846 1.000 81.36429  ? 150 ARG B CD  1 
ATOM   4948 N  NE  . ARG B 1 150 ? 28.79040  -18.05569 -71.39065 1.000 72.92082  ? 150 ARG B NE  1 
ATOM   4949 C  CZ  . ARG B 1 150 ? 29.32248  -19.18387 -70.94112 1.000 82.83469  ? 150 ARG B CZ  1 
ATOM   4950 N  NH1 . ARG B 1 150 ? 29.68216  -20.15446 -71.76523 1.000 78.09374  ? 150 ARG B NH1 1 
ATOM   4951 N  NH2 . ARG B 1 150 ? 29.50178  -19.34016 -69.63319 1.000 97.98192  ? 150 ARG B NH2 1 
ATOM   4952 N  N   . LEU B 1 151 ? 30.12935  -13.99911 -76.39098 1.000 69.58100  ? 151 LEU B N   1 
ATOM   4953 C  CA  . LEU B 1 151 ? 30.71195  -13.69830 -77.69054 1.000 75.08076  ? 151 LEU B CA  1 
ATOM   4954 C  C   . LEU B 1 151 ? 31.83102  -14.68547 -77.98595 1.000 68.52779  ? 151 LEU B C   1 
ATOM   4955 O  O   . LEU B 1 151 ? 32.58705  -15.06516 -77.08507 1.000 64.51726  ? 151 LEU B O   1 
ATOM   4956 C  CB  . LEU B 1 151 ? 31.25880  -12.26605 -77.73824 1.000 69.64580  ? 151 LEU B CB  1 
ATOM   4957 C  CG  . LEU B 1 151 ? 30.30629  -11.13813 -77.33799 1.000 57.73956  ? 151 LEU B CG  1 
ATOM   4958 C  CD1 . LEU B 1 151 ? 31.06492  -9.82979  -77.19945 1.000 63.38197  ? 151 LEU B CD1 1 
ATOM   4959 C  CD2 . LEU B 1 151 ? 29.18081  -11.00450 -78.34900 1.000 66.78535  ? 151 LEU B CD2 1 
ATOM   4960 N  N   . THR B 1 152 ? 31.93956  -15.09358 -79.25074 1.000 72.57696  ? 152 THR B N   1 
ATOM   4961 C  CA  . THR B 1 152 ? 32.99382  -16.01130 -79.65897 1.000 75.37496  ? 152 THR B CA  1 
ATOM   4962 C  C   . THR B 1 152 ? 33.28302  -15.82729 -81.14136 1.000 76.45229  ? 152 THR B C   1 
ATOM   4963 O  O   . THR B 1 152 ? 32.49037  -15.24023 -81.88365 1.000 72.50184  ? 152 THR B O   1 
ATOM   4964 C  CB  . THR B 1 152 ? 32.62484  -17.47263 -79.36899 1.000 62.01587  ? 152 THR B CB  1 
ATOM   4965 O  OG1 . THR B 1 152 ? 33.81492  -18.27148 -79.36503 1.000 69.42738  ? 152 THR B OG1 1 
ATOM   4966 C  CG2 . THR B 1 152 ? 31.67249  -18.00725 -80.43183 1.000 71.69108  ? 152 THR B CG2 1 
ATOM   4967 N  N   . VAL B 1 153 ? 34.43871  -16.33896 -81.56097 1.000 68.73675  ? 153 VAL B N   1 
ATOM   4968 C  CA  . VAL B 1 153 ? 34.88965  -16.27052 -82.94554 1.000 69.35757  ? 153 VAL B CA  1 
ATOM   4969 C  C   . VAL B 1 153 ? 35.01236  -17.68891 -83.48028 1.000 86.36392  ? 153 VAL B C   1 
ATOM   4970 O  O   . VAL B 1 153 ? 35.68804  -18.52910 -82.87592 1.000 85.96563  ? 153 VAL B O   1 
ATOM   4971 C  CB  . VAL B 1 153 ? 36.23047  -15.52360 -83.07500 1.000 58.94916  ? 153 VAL B CB  1 
ATOM   4972 C  CG1 . VAL B 1 153 ? 36.62012  -15.38379 -84.53824 1.000 64.12742  ? 153 VAL B CG1 1 
ATOM   4973 C  CG2 . VAL B 1 153 ? 36.14727  -14.16170 -82.40823 1.000 73.21677  ? 153 VAL B CG2 1 
ATOM   4974 N  N   . SER B 1 154 ? 34.35234  -17.95404 -84.60454 1.000 83.89262  ? 154 SER B N   1 
ATOM   4975 C  CA  . SER B 1 154 ? 34.46537  -19.23490 -85.29508 1.000 81.16999  ? 154 SER B CA  1 
ATOM   4976 C  C   . SER B 1 154 ? 34.45667  -18.96236 -86.79019 1.000 96.00123  ? 154 SER B C   1 
ATOM   4977 O  O   . SER B 1 154 ? 33.40806  -18.64117 -87.35532 1.000 104.80936 ? 154 SER B O   1 
ATOM   4978 C  CB  . SER B 1 154 ? 33.33168  -20.18404 -84.90783 1.000 92.42937  ? 154 SER B CB  1 
ATOM   4979 O  OG  . SER B 1 154 ? 33.42481  -21.40126 -85.62946 1.000 106.40088 ? 154 SER B OG  1 
ATOM   4980 N  N   . GLY B 1 155 ? 35.61745  -19.08929 -87.42646 1.000 93.76417  ? 155 GLY B N   1 
ATOM   4981 C  CA  . GLY B 1 155 ? 35.69226  -18.90735 -88.86250 1.000 98.04799  ? 155 GLY B CA  1 
ATOM   4982 C  C   . GLY B 1 155 ? 35.26749  -20.10513 -89.67498 1.000 103.43216 ? 155 GLY B C   1 
ATOM   4983 O  O   . GLY B 1 155 ? 35.22222  -20.02205 -90.90488 1.000 99.51759  ? 155 GLY B O   1 
ATOM   4984 N  N   . THR B 1 156 ? 34.95010  -21.21658 -89.01281 1.000 109.11575 ? 156 THR B N   1 
ATOM   4985 C  CA  . THR B 1 156 ? 34.56178  -22.45557 -89.67269 1.000 97.43537  ? 156 THR B CA  1 
ATOM   4986 C  C   . THR B 1 156 ? 33.05842  -22.70512 -89.59650 1.000 95.39692  ? 156 THR B C   1 
ATOM   4987 O  O   . THR B 1 156 ? 32.62388  -23.86016 -89.51784 1.000 98.89024  ? 156 THR B O   1 
ATOM   4988 C  CB  . THR B 1 156 ? 35.32186  -23.63582 -89.06972 1.000 109.05688 ? 156 THR B CB  1 
ATOM   4989 O  OG1 . THR B 1 156 ? 35.04298  -23.71610 -87.66702 1.000 119.21758 ? 156 THR B OG1 1 
ATOM   4990 C  CG2 . THR B 1 156 ? 36.81846  -23.45865 -89.27091 1.000 86.24954  ? 156 THR B CG2 1 
ATOM   4991 N  N   . GLY B 1 157 ? 32.25323  -21.64621 -89.62369 1.000 106.09581 ? 157 GLY B N   1 
ATOM   4992 C  CA  . GLY B 1 157 ? 30.81892  -21.77755 -89.54407 1.000 106.88559 ? 157 GLY B CA  1 
ATOM   4993 C  C   . GLY B 1 157 ? 30.28772  -21.50751 -88.15068 1.000 117.37080 ? 157 GLY B C   1 
ATOM   4994 O  O   . GLY B 1 157 ? 30.97550  -20.94047 -87.29624 1.000 120.20529 ? 157 GLY B O   1 
ATOM   4995 N  N   . PRO B 1 158 ? 29.04375  -21.91265 -87.89875 1.000 124.17089 ? 158 PRO B N   1 
ATOM   4996 C  CA  . PRO B 1 158 ? 28.45112  -21.67241 -86.58665 1.000 115.59413 ? 158 PRO B CA  1 
ATOM   4997 C  C   . PRO B 1 158 ? 29.21653  -22.40907 -85.50576 1.000 116.04636 ? 158 PRO B C   1 
ATOM   4998 O  O   . PRO B 1 158 ? 29.83368  -23.46125 -85.75988 1.000 112.27294 ? 158 PRO B O   1 
ATOM   4999 C  CB  . PRO B 1 158 ? 27.02026  -22.21106 -86.73864 1.000 99.34302  ? 158 PRO B CB  1 
ATOM   5000 C  CG  . PRO B 1 158 ? 27.05907  -23.11164 -87.92288 1.000 112.14308 ? 158 PRO B CG  1 
ATOM   5001 C  CD  . PRO B 1 158 ? 28.09612  -22.54159 -88.83381 1.000 115.72644 ? 158 PRO B CD  1 
ATOM   5002 N  N   . PRO B 1 159 ? 29.20218  -21.89086 -84.27915 1.000 113.74442 ? 159 PRO B N   1 
ATOM   5003 C  CA  . PRO B 1 159 ? 30.04476  -22.44939 -83.21524 1.000 106.68308 ? 159 PRO B CA  1 
ATOM   5004 C  C   . PRO B 1 159 ? 29.67242  -23.87937 -82.85447 1.000 114.23514 ? 159 PRO B C   1 
ATOM   5005 O  O   . PRO B 1 159 ? 28.54365  -24.33695 -83.04943 1.000 116.27789 ? 159 PRO B O   1 
ATOM   5006 C  CB  . PRO B 1 159 ? 29.79383  -21.50514 -82.03252 1.000 94.32497  ? 159 PRO B CB  1 
ATOM   5007 C  CG  . PRO B 1 159 ? 29.29109  -20.24343 -82.65232 1.000 94.14963  ? 159 PRO B CG  1 
ATOM   5008 C  CD  . PRO B 1 159 ? 28.49492  -20.67837 -83.84041 1.000 105.84662 ? 159 PRO B CD  1 
ATOM   5009 N  N   . ALA B 1 160 ? 30.66821  -24.58689 -82.31439 1.000 116.01768 ? 160 ALA B N   1 
ATOM   5010 C  CA  . ALA B 1 160 ? 30.54019  -25.99853 -81.95138 1.000 116.79149 ? 160 ALA B CA  1 
ATOM   5011 C  C   . ALA B 1 160 ? 29.93825  -26.12675 -80.55024 1.000 112.77724 ? 160 ALA B C   1 
ATOM   5012 O  O   . ALA B 1 160 ? 30.59375  -26.51190 -79.57871 1.000 105.39654 ? 160 ALA B O   1 
ATOM   5013 C  CB  . ALA B 1 160 ? 31.89314  -26.69047 -82.04516 1.000 97.23907  ? 160 ALA B CB  1 
ATOM   5014 N  N   . ASN B 1 161 ? 28.65379  -25.79052 -80.46656 1.000 109.85053 ? 161 ASN B N   1 
ATOM   5015 C  CA  . ASN B 1 161 ? 27.85091  -25.97443 -79.26525 1.000 101.57364 ? 161 ASN B CA  1 
ATOM   5016 C  C   . ASN B 1 161 ? 26.39610  -25.76123 -79.64873 1.000 101.47114 ? 161 ASN B C   1 
ATOM   5017 O  O   . ASN B 1 161 ? 26.09391  -25.16148 -80.68460 1.000 99.56955  ? 161 ASN B O   1 
ATOM   5018 C  CB  . ASN B 1 161 ? 28.26440  -25.01519 -78.14063 1.000 101.22230 ? 161 ASN B CB  1 
ATOM   5019 C  CG  . ASN B 1 161 ? 27.57556  -25.33199 -76.82480 1.000 100.14932 ? 161 ASN B CG  1 
ATOM   5020 O  OD1 . ASN B 1 161 ? 26.69527  -24.59583 -76.37796 1.000 106.46648 ? 161 ASN B OD1 1 
ATOM   5021 N  ND2 . ASN B 1 161 ? 27.96238  -26.44192 -76.20689 1.000 78.63485  ? 161 ASN B ND2 1 
ATOM   5022 N  N   . SER B 1 162 ? 25.49786  -26.27639 -78.81329 1.000 96.57144  ? 162 SER B N   1 
ATOM   5023 C  CA  . SER B 1 162 ? 24.07631  -26.08770 -79.05096 1.000 96.75268  ? 162 SER B CA  1 
ATOM   5024 C  C   . SER B 1 162 ? 23.27102  -25.79636 -77.79241 1.000 99.54566  ? 162 SER B C   1 
ATOM   5025 O  O   . SER B 1 162 ? 22.05346  -25.61912 -77.89416 1.000 100.49726 ? 162 SER B O   1 
ATOM   5026 C  CB  . SER B 1 162 ? 23.49455  -27.31028 -79.76383 1.000 100.02060 ? 162 SER B CB  1 
ATOM   5027 O  OG  . SER B 1 162 ? 24.35619  -27.76790 -80.79099 1.000 106.27389 ? 162 SER B OG  1 
ATOM   5028 N  N   . GLY B 1 163 ? 23.89785  -25.73905 -76.61638 1.000 86.74176  ? 163 GLY B N   1 
ATOM   5029 C  CA  . GLY B 1 163 ? 23.21863  -25.19494 -75.45068 1.000 87.86628  ? 163 GLY B CA  1 
ATOM   5030 C  C   . GLY B 1 163 ? 22.90114  -23.72200 -75.57746 1.000 99.91894  ? 163 GLY B C   1 
ATOM   5031 O  O   . GLY B 1 163 ? 22.24151  -23.15899 -74.69556 1.000 99.22776  ? 163 GLY B O   1 
ATOM   5032 N  N   . CYS B 1 164 ? 23.37448  -23.09035 -76.64723 1.000 101.65572 ? 164 CYS B N   1 
ATOM   5033 C  CA  . CYS B 1 164 ? 23.08930  -21.70949 -76.99347 1.000 79.73977  ? 164 CYS B CA  1 
ATOM   5034 C  C   . CYS B 1 164 ? 22.76504  -21.66777 -78.47841 1.000 85.59483  ? 164 CYS B C   1 
ATOM   5035 O  O   . CYS B 1 164 ? 23.42097  -22.34954 -79.27269 1.000 95.94066  ? 164 CYS B O   1 
ATOM   5036 C  CB  . CYS B 1 164 ? 24.29727  -20.81639 -76.68814 1.000 84.88428  ? 164 CYS B CB  1 
ATOM   5037 S  SG  . CYS B 1 164 ? 23.96754  -19.32860 -75.73677 1.000 128.23989 ? 164 CYS B SG  1 
ATOM   5038 N  N   . GLU B 1 165 ? 21.75544  -20.88657 -78.86106 1.000 93.31116  ? 165 GLU B N   1 
ATOM   5039 C  CA  . GLU B 1 165 ? 21.48232  -20.66537 -80.28174 1.000 95.40843  ? 165 GLU B CA  1 
ATOM   5040 C  C   . GLU B 1 165 ? 22.33799  -19.49143 -80.73623 1.000 84.06847  ? 165 GLU B C   1 
ATOM   5041 O  O   . GLU B 1 165 ? 21.95056  -18.32851 -80.59465 1.000 85.16916  ? 165 GLU B O   1 
ATOM   5042 C  CB  . GLU B 1 165 ? 20.00696  -20.40751 -80.55737 1.000 102.71649 ? 165 GLU B CB  1 
ATOM   5043 C  CG  . GLU B 1 165 ? 19.73571  -20.28861 -82.05959 1.000 101.23369 ? 165 GLU B CG  1 
ATOM   5044 C  CD  . GLU B 1 165 ? 18.30632  -19.92475 -82.40090 1.000 117.01126 ? 165 GLU B CD  1 
ATOM   5045 O  OE1 . GLU B 1 165 ? 17.49140  -19.75604 -81.47185 1.000 124.95502 ? 165 GLU B OE1 1 
ATOM   5046 O  OE2 . GLU B 1 165 ? 18.00158  -19.80803 -83.60843 1.000 109.76341 ? 165 GLU B OE2 1 
ATOM   5047 N  N   . TRP B 1 166 ? 23.50516  -19.79918 -81.28414 1.000 82.68891  ? 166 TRP B N   1 
ATOM   5048 C  CA  . TRP B 1 166 ? 24.42887  -18.76086 -81.71607 1.000 85.35899  ? 166 TRP B CA  1 
ATOM   5049 C  C   . TRP B 1 166 ? 23.90781  -18.06879 -82.96805 1.000 84.80004  ? 166 TRP B C   1 
ATOM   5050 O  O   . TRP B 1 166 ? 23.44112  -18.71961 -83.90809 1.000 78.18608  ? 166 TRP B O   1 
ATOM   5051 C  CB  . TRP B 1 166 ? 25.81258  -19.35965 -81.97174 1.000 78.65758  ? 166 TRP B CB  1 
ATOM   5052 C  CG  . TRP B 1 166 ? 26.42006  -19.94796 -80.74251 1.000 80.29757  ? 166 TRP B CG  1 
ATOM   5053 C  CD1 . TRP B 1 166 ? 26.26179  -21.22028 -80.27932 1.000 89.57042  ? 166 TRP B CD1 1 
ATOM   5054 C  CD2 . TRP B 1 166 ? 27.28451  -19.28594 -79.81313 1.000 88.47050  ? 166 TRP B CD2 1 
ATOM   5055 N  NE1 . TRP B 1 166 ? 26.97480  -21.39260 -79.11805 1.000 89.84318  ? 166 TRP B NE1 1 
ATOM   5056 C  CE2 . TRP B 1 166 ? 27.61247  -20.21956 -78.81089 1.000 82.73084  ? 166 TRP B CE2 1 
ATOM   5057 C  CE3 . TRP B 1 166 ? 27.81369  -17.99471 -79.73174 1.000 84.01453  ? 166 TRP B CE3 1 
ATOM   5058 C  CZ2 . TRP B 1 166 ? 28.44533  -19.90355 -77.74064 1.000 82.62028  ? 166 TRP B CZ2 1 
ATOM   5059 C  CZ3 . TRP B 1 166 ? 28.63967  -17.68221 -78.66775 1.000 88.04925  ? 166 TRP B CZ3 1 
ATOM   5060 C  CH2 . TRP B 1 166 ? 28.94813  -18.63319 -77.68697 1.000 78.26498  ? 166 TRP B CH2 1 
ATOM   5061 N  N   . LYS B 1 167 ? 23.98447  -16.74352 -82.97130 1.000 78.33789  ? 167 LYS B N   1 
ATOM   5062 C  CA  . LYS B 1 167 ? 23.55111  -15.92670 -84.09048 1.000 70.53880  ? 167 LYS B CA  1 
ATOM   5063 C  C   . LYS B 1 167 ? 24.67191  -14.96588 -84.45363 1.000 87.16451  ? 167 LYS B C   1 
ATOM   5064 O  O   . LYS B 1 167 ? 25.49147  -14.60000 -83.61012 1.000 87.06197  ? 167 LYS B O   1 
ATOM   5065 C  CB  . LYS B 1 167 ? 22.27627  -15.14932 -83.75026 1.000 75.85831  ? 167 LYS B CB  1 
ATOM   5066 C  CG  . LYS B 1 167 ? 21.18082  -16.00946 -83.13347 1.000 79.41736  ? 167 LYS B CG  1 
ATOM   5067 C  CD  . LYS B 1 167 ? 20.06166  -15.16846 -82.54435 1.000 89.33582  ? 167 LYS B CD  1 
ATOM   5068 C  CE  . LYS B 1 167 ? 19.00930  -16.03992 -81.87571 1.000 87.93303  ? 167 LYS B CE  1 
ATOM   5069 N  NZ  . LYS B 1 167 ? 17.88471  -15.23693 -81.32057 1.000 83.39155  ? 167 LYS B NZ  1 
ATOM   5070 N  N   . LEU B 1 168 ? 24.70650  -14.55596 -85.71475 1.000 80.41793  ? 168 LEU B N   1 
ATOM   5071 C  CA  . LEU B 1 168 ? 25.72103  -13.60396 -86.14271 1.000 69.96204  ? 168 LEU B CA  1 
ATOM   5072 C  C   . LEU B 1 168 ? 25.41558  -12.23271 -85.55530 1.000 79.95258  ? 168 LEU B C   1 
ATOM   5073 O  O   . LEU B 1 168 ? 24.27913  -11.75399 -85.62674 1.000 83.80949  ? 168 LEU B O   1 
ATOM   5074 C  CB  . LEU B 1 168 ? 25.78518  -13.53554 -87.67098 1.000 78.12914  ? 168 LEU B CB  1 
ATOM   5075 C  CG  . LEU B 1 168 ? 26.73326  -14.54730 -88.31497 1.000 85.10528  ? 168 LEU B CG  1 
ATOM   5076 C  CD1 . LEU B 1 168 ? 26.70488  -14.42920 -89.83031 1.000 75.57883  ? 168 LEU B CD1 1 
ATOM   5077 C  CD2 . LEU B 1 168 ? 28.14815  -14.35787 -87.78711 1.000 78.40865  ? 168 LEU B CD2 1 
ATOM   5078 N  N   . VAL B 1 169 ? 26.43351  -11.61233 -84.95314 1.000 75.55276  ? 169 VAL B N   1 
ATOM   5079 C  CA  . VAL B 1 169 ? 26.25931  -10.28901 -84.35923 1.000 82.66767  ? 169 VAL B CA  1 
ATOM   5080 C  C   . VAL B 1 169 ? 25.77915  -9.29791  -85.40990 1.000 87.65670  ? 169 VAL B C   1 
ATOM   5081 O  O   . VAL B 1 169 ? 25.00223  -8.38183  -85.11495 1.000 93.98821  ? 169 VAL B O   1 
ATOM   5082 C  CB  . VAL B 1 169 ? 27.56894  -9.82408  -83.69269 1.000 82.32267  ? 169 VAL B CB  1 
ATOM   5083 C  CG1 . VAL B 1 169 ? 27.39482  -8.45240  -83.05725 1.000 79.32566  ? 169 VAL B CG1 1 
ATOM   5084 C  CG2 . VAL B 1 169 ? 28.01979  -10.83794 -82.65506 1.000 79.85930  ? 169 VAL B CG2 1 
ATOM   5085 N  N   . GLU B 1 170 ? 26.22442  -9.47240  -86.65416 1.000 82.34148  ? 170 GLU B N   1 
ATOM   5086 C  CA  . GLU B 1 170 ? 25.78254  -8.59936  -87.73681 1.000 88.74537  ? 170 GLU B CA  1 
ATOM   5087 C  C   . GLU B 1 170 ? 24.27456  -8.69276  -87.94314 1.000 92.56405  ? 170 GLU B C   1 
ATOM   5088 O  O   . GLU B 1 170 ? 23.59129  -7.67184  -88.08449 1.000 90.42536  ? 170 GLU B O   1 
ATOM   5089 C  CB  . GLU B 1 170 ? 26.52959  -8.96005  -89.02040 1.000 98.30490  ? 170 GLU B CB  1 
ATOM   5090 C  CG  . GLU B 1 170 ? 26.14949  -8.13743  -90.23686 1.000 105.69708 ? 170 GLU B CG  1 
ATOM   5091 C  CD  . GLU B 1 170 ? 27.01423  -8.46226  -91.44032 1.000 114.56394 ? 170 GLU B CD  1 
ATOM   5092 O  OE1 . GLU B 1 170 ? 27.08119  -9.64979  -91.82551 1.000 108.07505 ? 170 GLU B OE1 1 
ATOM   5093 O  OE2 . GLU B 1 170 ? 27.63850  -7.53033  -91.99027 1.000 123.13628 ? 170 GLU B OE2 1 
ATOM   5094 N  N   . THR B 1 171 ? 23.73728  -9.91535  -87.95671 1.000 78.00206  ? 171 THR B N   1 
ATOM   5095 C  CA  . THR B 1 171 ? 22.31357  -10.10260 -88.22456 1.000 77.12489  ? 171 THR B CA  1 
ATOM   5096 C  C   . THR B 1 171 ? 21.45705  -9.58737  -87.07344 1.000 78.44107  ? 171 THR B C   1 
ATOM   5097 O  O   . THR B 1 171 ? 20.46712  -8.87890  -87.29242 1.000 81.69980  ? 171 THR B O   1 
ATOM   5098 C  CB  . THR B 1 171 ? 22.01947  -11.57882 -88.48842 1.000 83.80544  ? 171 THR B CB  1 
ATOM   5099 O  OG1 . THR B 1 171 ? 22.90668  -12.06906 -89.50015 1.000 81.56820  ? 171 THR B OG1 1 
ATOM   5100 C  CG2 . THR B 1 171 ? 20.58207  -11.75632 -88.95332 1.000 83.68578  ? 171 THR B CG2 1 
ATOM   5101 N  N   . GLU B 1 172 ? 21.81661  -9.94229  -85.83692 1.000 85.17627  ? 172 GLU B N   1 
ATOM   5102 C  CA  . GLU B 1 172 ? 21.06333  -9.46104  -84.68302 1.000 85.26914  ? 172 GLU B CA  1 
ATOM   5103 C  C   . GLU B 1 172 ? 21.14257  -7.94567  -84.55787 1.000 83.98910  ? 172 GLU B C   1 
ATOM   5104 O  O   . GLU B 1 172 ? 20.18960  -7.30807  -84.09537 1.000 85.07369  ? 172 GLU B O   1 
ATOM   5105 C  CB  . GLU B 1 172 ? 21.57311  -10.13337 -83.40803 1.000 85.52899  ? 172 GLU B CB  1 
ATOM   5106 C  CG  . GLU B 1 172 ? 21.17706  -11.59435 -83.28773 1.000 73.37855  ? 172 GLU B CG  1 
ATOM   5107 C  CD  . GLU B 1 172 ? 19.68714  -11.76897 -83.07216 1.000 86.26910  ? 172 GLU B CD  1 
ATOM   5108 O  OE1 . GLU B 1 172 ? 19.15559  -11.18724 -82.10260 1.000 81.74255  ? 172 GLU B OE1 1 
ATOM   5109 O  OE2 . GLU B 1 172 ? 19.04558  -12.47524 -83.87836 1.000 91.40172  ? 172 GLU B OE2 1 
ATOM   5110 N  N   . ARG B 1 173 ? 22.26913  -7.35510  -84.96056 1.000 89.30534  ? 173 ARG B N   1 
ATOM   5111 C  CA  . ARG B 1 173 ? 22.39152  -5.90155  -84.96073 1.000 85.30363  ? 173 ARG B CA  1 
ATOM   5112 C  C   . ARG B 1 173 ? 21.55289  -5.27784  -86.07103 1.000 91.78705  ? 173 ARG B C   1 
ATOM   5113 O  O   . ARG B 1 173 ? 20.97841  -4.19782  -85.89090 1.000 75.78030  ? 173 ARG B O   1 
ATOM   5114 C  CB  . ARG B 1 173 ? 23.86245  -5.50635  -85.10038 1.000 79.98639  ? 173 ARG B CB  1 
ATOM   5115 C  CG  . ARG B 1 173 ? 24.11690  -4.01544  -85.21145 1.000 78.03873  ? 173 ARG B CG  1 
ATOM   5116 C  CD  . ARG B 1 173 ? 25.59626  -3.70984  -85.42998 1.000 78.84589  ? 173 ARG B CD  1 
ATOM   5117 N  NE  . ARG B 1 173 ? 26.41778  -4.04115  -84.27078 1.000 73.48689  ? 173 ARG B NE  1 
ATOM   5118 C  CZ  . ARG B 1 173 ? 27.41138  -4.91999  -84.27785 1.000 77.04003  ? 173 ARG B CZ  1 
ATOM   5119 N  NH1 . ARG B 1 173 ? 27.74804  -5.57504  -85.37725 1.000 78.34052  ? 173 ARG B NH1 1 
ATOM   5120 N  NH2 . ARG B 1 173 ? 28.09110  -5.13988  -83.15590 1.000 80.94329  ? 173 ARG B NH2 1 
ATOM   5121 N  N   . ALA B 1 174 ? 21.47060  -5.94334  -87.22625 1.000 92.74411  ? 174 ALA B N   1 
ATOM   5122 C  CA  . ALA B 1 174 ? 20.71534  -5.39472  -88.34919 1.000 88.20952  ? 174 ALA B CA  1 
ATOM   5123 C  C   . ALA B 1 174 ? 19.21553  -5.40369  -88.07454 1.000 93.11866  ? 174 ALA B C   1 
ATOM   5124 O  O   . ALA B 1 174 ? 18.52570  -4.41197  -88.33560 1.000 103.57255 ? 174 ALA B O   1 
ATOM   5125 C  CB  . ALA B 1 174 ? 21.03319  -6.17623  -89.62476 1.000 81.82127  ? 174 ALA B CB  1 
ATOM   5126 N  N   . ASN B 1 175 ? 18.69394  -6.50439  -87.53653 1.000 85.78743  ? 175 ASN B N   1 
ATOM   5127 C  CA  . ASN B 1 175 ? 17.26348  -6.64238  -87.29034 1.000 83.98816  ? 175 ASN B CA  1 
ATOM   5128 C  C   . ASN B 1 175 ? 16.78698  -5.85464  -86.07421 1.000 89.76245  ? 175 ASN B C   1 
ATOM   5129 O  O   . ASN B 1 175 ? 15.64353  -6.03850  -85.64610 1.000 96.14872  ? 175 ASN B O   1 
ATOM   5130 C  CB  . ASN B 1 175 ? 16.89885  -8.12066  -87.13352 1.000 82.57518  ? 175 ASN B CB  1 
ATOM   5131 C  CG  . ASN B 1 175 ? 17.06576  -8.89968  -88.42489 1.000 94.00443  ? 175 ASN B CG  1 
ATOM   5132 O  OD1 . ASN B 1 175 ? 16.71038  -8.42060  -89.50340 1.000 105.02065 ? 175 ASN B OD1 1 
ATOM   5133 N  ND2 . ASN B 1 175 ? 17.62002  -10.10120 -88.32337 1.000 85.63029  ? 175 ASN B ND2 1 
ATOM   5134 N  N   . SER B 1 176 ? 17.62482  -4.98891  -85.51324 1.000 81.34787  ? 176 SER B N   1 
ATOM   5135 C  CA  . SER B 1 176 ? 17.23763  -4.13720  -84.39979 1.000 84.06642  ? 176 SER B CA  1 
ATOM   5136 C  C   . SER B 1 176 ? 16.89771  -2.74727  -84.91719 1.000 97.73171  ? 176 SER B C   1 
ATOM   5137 O  O   . SER B 1 176 ? 17.55466  -2.23385  -85.82834 1.000 99.88359  ? 176 SER B O   1 
ATOM   5138 C  CB  . SER B 1 176 ? 18.35114  -4.04727  -83.35616 1.000 88.15179  ? 176 SER B CB  1 
ATOM   5139 O  OG  . SER B 1 176 ? 19.43188  -3.26235  -83.82956 1.000 111.57156 ? 176 SER B OG  1 
ATOM   5140 N  N   . GLY B 1 177 ? 15.87369  -2.13744  -84.32284 1.000 95.64412  ? 177 GLY B N   1 
ATOM   5141 C  CA  . GLY B 1 177 ? 15.45446  -0.81150  -84.72597 1.000 84.13571  ? 177 GLY B CA  1 
ATOM   5142 C  C   . GLY B 1 177 ? 16.39772  0.29815   -84.33122 1.000 100.22927 ? 177 GLY B C   1 
ATOM   5143 O  O   . GLY B 1 177 ? 16.10734  1.46868   -84.59696 1.000 102.59049 ? 177 GLY B O   1 
ATOM   5144 N  N   . ASP B 1 178 ? 17.51155  -0.03315  -83.68500 1.000 110.75035 ? 178 ASP B N   1 
ATOM   5145 C  CA  . ASP B 1 178 ? 18.48583  0.97365   -83.27509 1.000 107.32457 ? 178 ASP B CA  1 
ATOM   5146 C  C   . ASP B 1 178 ? 19.84456  0.29982   -83.17948 1.000 106.07749 ? 178 ASP B C   1 
ATOM   5147 O  O   . ASP B 1 178 ? 20.02042  -0.62601  -82.38142 1.000 104.21233 ? 178 ASP B O   1 
ATOM   5148 C  CB  . ASP B 1 178 ? 18.08177  1.60564   -81.94440 1.000 91.81335  ? 178 ASP B CB  1 
ATOM   5149 C  CG  . ASP B 1 178 ? 18.82782  2.88825   -81.65136 1.000 101.69048 ? 178 ASP B CG  1 
ATOM   5150 O  OD1 . ASP B 1 178 ? 20.06682  2.91624   -81.80671 1.000 107.74426 ? 178 ASP B OD1 1 
ATOM   5151 O  OD2 . ASP B 1 178 ? 18.16763  3.87500   -81.27294 1.000 111.98633 ? 178 ASP B OD2 1 
ATOM   5152 N  N   . ILE B 1 179 ? 20.79676  0.74599   -84.00234 1.000 107.18729 ? 179 ILE B N   1 
ATOM   5153 C  CA  . ILE B 1 179 ? 22.13042  0.15275   -83.98570 1.000 87.75075  ? 179 ILE B CA  1 
ATOM   5154 C  C   . ILE B 1 179 ? 22.88806  0.55590   -82.72604 1.000 78.01744  ? 179 ILE B C   1 
ATOM   5155 O  O   . ILE B 1 179 ? 23.75438  -0.18828  -82.24922 1.000 92.78957  ? 179 ILE B O   1 
ATOM   5156 C  CB  . ILE B 1 179 ? 22.90285  0.54231   -85.25961 1.000 92.29643  ? 179 ILE B CB  1 
ATOM   5157 C  CG1 . ILE B 1 179 ? 22.03404  0.31364   -86.49817 1.000 95.91923  ? 179 ILE B CG1 1 
ATOM   5158 C  CG2 . ILE B 1 179 ? 24.18660  -0.26182  -85.37314 1.000 74.95929  ? 179 ILE B CG2 1 
ATOM   5159 C  CD1 . ILE B 1 179 ? 21.52690  -1.10127  -86.64054 1.000 99.16348  ? 179 ILE B CD1 1 
ATOM   5160 N  N   . ALA B 1 180 ? 22.58665  1.73183   -82.17148 1.000 71.53401  ? 180 ALA B N   1 
ATOM   5161 C  CA  . ALA B 1 180 ? 23.22832  2.17517   -80.93834 1.000 78.29192  ? 180 ALA B CA  1 
ATOM   5162 C  C   . ALA B 1 180 ? 22.67411  1.45414   -79.71434 1.000 88.31641  ? 180 ALA B C   1 
ATOM   5163 O  O   . ALA B 1 180 ? 23.42432  1.15277   -78.77984 1.000 83.78361  ? 180 ALA B O   1 
ATOM   5164 C  CB  . ALA B 1 180 ? 23.06867  3.68751   -80.77793 1.000 75.23770  ? 180 ALA B CB  1 
ATOM   5165 N  N   . ALA B 1 181 ? 21.36738  1.17705   -79.69436 1.000 86.10513  ? 181 ALA B N   1 
ATOM   5166 C  CA  . ALA B 1 181 ? 20.77987  0.47062   -78.55863 1.000 76.04232  ? 181 ALA B CA  1 
ATOM   5167 C  C   . ALA B 1 181 ? 21.35402  -0.93432  -78.42460 1.000 85.74637  ? 181 ALA B C   1 
ATOM   5168 O  O   . ALA B 1 181 ? 21.62986  -1.39700  -77.31168 1.000 89.95093  ? 181 ALA B O   1 
ATOM   5169 C  CB  . ALA B 1 181 ? 19.25817  0.41891   -78.70201 1.000 64.16626  ? 181 ALA B CB  1 
ATOM   5170 N  N   . PHE B 1 182 ? 21.53211  -1.63067  -79.54867 1.000 84.59058  ? 182 PHE B N   1 
ATOM   5171 C  CA  . PHE B 1 182 ? 22.14571  -2.95469  -79.51619 1.000 84.39407  ? 182 PHE B CA  1 
ATOM   5172 C  C   . PHE B 1 182 ? 23.57897  -2.88798  -79.00130 1.000 82.76174  ? 182 PHE B C   1 
ATOM   5173 O  O   . PHE B 1 182 ? 23.99492  -3.72259  -78.18978 1.000 93.85318  ? 182 PHE B O   1 
ATOM   5174 C  CB  . PHE B 1 182 ? 22.09781  -3.57956  -80.91240 1.000 78.97697  ? 182 PHE B CB  1 
ATOM   5175 C  CG  . PHE B 1 182 ? 22.80171  -4.90397  -81.01756 1.000 70.17604  ? 182 PHE B CG  1 
ATOM   5176 C  CD1 . PHE B 1 182 ? 24.14655  -4.96415  -81.35016 1.000 76.53286  ? 182 PHE B CD1 1 
ATOM   5177 C  CD2 . PHE B 1 182 ? 22.11644  -6.08822  -80.80414 1.000 66.94844  ? 182 PHE B CD2 1 
ATOM   5178 C  CE1 . PHE B 1 182 ? 24.79712  -6.17510  -81.45109 1.000 79.67057  ? 182 PHE B CE1 1 
ATOM   5179 C  CE2 . PHE B 1 182 ? 22.76396  -7.30473  -80.90790 1.000 82.80113  ? 182 PHE B CE2 1 
ATOM   5180 C  CZ  . PHE B 1 182 ? 24.10587  -7.34550  -81.23207 1.000 80.95773  ? 182 PHE B CZ  1 
ATOM   5181 N  N   . ASP B 1 183 ? 24.34819  -1.89951  -79.45851 1.000 70.98062  ? 183 ASP B N   1 
ATOM   5182 C  CA  . ASP B 1 183 ? 25.74654  -1.77726  -79.06707 1.000 74.85038  ? 183 ASP B CA  1 
ATOM   5183 C  C   . ASP B 1 183 ? 25.93217  -1.12922  -77.70220 1.000 80.16047  ? 183 ASP B C   1 
ATOM   5184 O  O   . ASP B 1 183 ? 27.06099  -1.09308  -77.20101 1.000 82.88745  ? 183 ASP B O   1 
ATOM   5185 C  CB  . ASP B 1 183 ? 26.51724  -0.99348  -80.13003 1.000 75.69014  ? 183 ASP B CB  1 
ATOM   5186 C  CG  . ASP B 1 183 ? 26.70901  -1.79008  -81.40614 1.000 81.62213  ? 183 ASP B CG  1 
ATOM   5187 O  OD1 . ASP B 1 183 ? 27.14853  -2.95798  -81.32365 1.000 82.56501  ? 183 ASP B OD1 1 
ATOM   5188 O  OD2 . ASP B 1 183 ? 26.39143  -1.26048  -82.48997 1.000 82.99730  ? 183 ASP B OD2 1 
ATOM   5189 N  N   . HIS B 1 184 ? 24.86678  -0.60843  -77.09866 1.000 76.76090  ? 184 HIS B N   1 
ATOM   5190 C  CA  . HIS B 1 184 ? 24.92049  -0.21592  -75.69765 1.000 76.88026  ? 184 HIS B CA  1 
ATOM   5191 C  C   . HIS B 1 184 ? 24.44511  -1.34255  -74.79266 1.000 86.03063  ? 184 HIS B C   1 
ATOM   5192 O  O   . HIS B 1 184 ? 24.97566  -1.51972  -73.69200 1.000 94.05485  ? 184 HIS B O   1 
ATOM   5193 C  CB  . HIS B 1 184 ? 24.07862  1.03709   -75.45361 1.000 80.41539  ? 184 HIS B CB  1 
ATOM   5194 C  CG  . HIS B 1 184 ? 24.14390  1.53763   -74.04484 1.000 93.58281  ? 184 HIS B CG  1 
ATOM   5195 N  ND1 . HIS B 1 184 ? 25.10901  2.42150   -73.61346 1.000 102.49606 ? 184 HIS B ND1 1 
ATOM   5196 C  CD2 . HIS B 1 184 ? 23.37373  1.26509   -72.96525 1.000 80.94376  ? 184 HIS B CD2 1 
ATOM   5197 C  CE1 . HIS B 1 184 ? 24.92385  2.68060   -72.33148 1.000 88.81016  ? 184 HIS B CE1 1 
ATOM   5198 N  NE2 . HIS B 1 184 ? 23.87773  1.99117   -71.91381 1.000 94.11857  ? 184 HIS B NE2 1 
ATOM   5199 N  N   . TRP B 1 185 ? 23.44738  -2.10540  -75.24515 1.000 82.16662  ? 185 TRP B N   1 
ATOM   5200 C  CA  . TRP B 1 185 ? 23.02398  -3.29575  -74.51704 1.000 77.73720  ? 185 TRP B CA  1 
ATOM   5201 C  C   . TRP B 1 185 ? 24.12236  -4.35027  -74.49974 1.000 78.42962  ? 185 TRP B C   1 
ATOM   5202 O  O   . TRP B 1 185 ? 24.26912  -5.08479  -73.51533 1.000 89.23499  ? 185 TRP B O   1 
ATOM   5203 C  CB  . TRP B 1 185 ? 21.74661  -3.86135  -75.13909 1.000 78.22042  ? 185 TRP B CB  1 
ATOM   5204 C  CG  . TRP B 1 185 ? 21.42783  -5.26198  -74.70550 1.000 87.14546  ? 185 TRP B CG  1 
ATOM   5205 C  CD1 . TRP B 1 185 ? 20.75924  -5.64020  -73.57711 1.000 83.69090  ? 185 TRP B CD1 1 
ATOM   5206 C  CD2 . TRP B 1 185 ? 21.76188  -6.47178  -75.39790 1.000 83.85293  ? 185 TRP B CD2 1 
ATOM   5207 N  NE1 . TRP B 1 185 ? 20.65854  -7.00954  -73.52327 1.000 88.15090  ? 185 TRP B NE1 1 
ATOM   5208 C  CE2 . TRP B 1 185 ? 21.26658  -7.54351  -74.62883 1.000 89.86068  ? 185 TRP B CE2 1 
ATOM   5209 C  CE3 . TRP B 1 185 ? 22.43361  -6.75237  -76.59197 1.000 81.55728  ? 185 TRP B CE3 1 
ATOM   5210 C  CZ2 . TRP B 1 185 ? 21.41853  -8.87269  -75.01640 1.000 88.34796  ? 185 TRP B CZ2 1 
ATOM   5211 C  CZ3 . TRP B 1 185 ? 22.58532  -8.07333  -76.97364 1.000 90.40578  ? 185 TRP B CZ3 1 
ATOM   5212 C  CH2 . TRP B 1 185 ? 22.08028  -9.11650  -76.18826 1.000 83.28939  ? 185 TRP B CH2 1 
ATOM   5213 N  N   . LEU B 1 186 ? 24.89140  -4.45280  -75.58711 1.000 80.97829  ? 186 LEU B N   1 
ATOM   5214 C  CA  . LEU B 1 186 ? 25.99213  -5.40872  -75.62351 1.000 81.45131  ? 186 LEU B CA  1 
ATOM   5215 C  C   . LEU B 1 186 ? 27.01609  -5.11822  -74.53734 1.000 74.96846  ? 186 LEU B C   1 
ATOM   5216 O  O   . LEU B 1 186 ? 27.62488  -6.04652  -73.99778 1.000 89.14622  ? 186 LEU B O   1 
ATOM   5217 C  CB  . LEU B 1 186 ? 26.65740  -5.38686  -77.00145 1.000 73.70410  ? 186 LEU B CB  1 
ATOM   5218 C  CG  . LEU B 1 186 ? 27.44622  -6.63864  -77.37799 1.000 73.80261  ? 186 LEU B CG  1 
ATOM   5219 C  CD1 . LEU B 1 186 ? 26.54916  -7.85982  -77.28508 1.000 86.18499  ? 186 LEU B CD1 1 
ATOM   5220 C  CD2 . LEU B 1 186 ? 28.02288  -6.50786  -78.77577 1.000 84.48722  ? 186 LEU B CD2 1 
ATOM   5221 N  N   . LYS B 1 187 ? 27.22013  -3.84303  -74.20663 1.000 64.97330  ? 187 LYS B N   1 
ATOM   5222 C  CA  . LYS B 1 187 ? 28.07678  -3.49040  -73.08189 1.000 76.74709  ? 187 LYS B CA  1 
ATOM   5223 C  C   . LYS B 1 187 ? 27.32851  -3.59306  -71.75835 1.000 74.35933  ? 187 LYS B C   1 
ATOM   5224 O  O   . LYS B 1 187 ? 27.87806  -4.08989  -70.77114 1.000 64.99930  ? 187 LYS B O   1 
ATOM   5225 C  CB  . LYS B 1 187 ? 28.63155  -2.07661  -73.27286 1.000 71.85791  ? 187 LYS B CB  1 
ATOM   5226 C  CG  . LYS B 1 187 ? 29.48591  -1.57094  -72.12288 1.000 65.72385  ? 187 LYS B CG  1 
ATOM   5227 C  CD  . LYS B 1 187 ? 29.84301  -0.10861  -72.31623 1.000 60.70004  ? 187 LYS B CD  1 
ATOM   5228 C  CE  . LYS B 1 187 ? 30.76377  0.38364   -71.21699 1.000 73.35760  ? 187 LYS B CE  1 
ATOM   5229 N  NZ  . LYS B 1 187 ? 31.05852  1.83283   -71.37476 1.000 90.83080  ? 187 LYS B NZ  1 
ATOM   5230 N  N   . SER B 1 188 ? 26.07204  -3.14126  -71.72540 1.000 73.76883  ? 188 SER B N   1 
ATOM   5231 C  CA  . SER B 1 188 ? 25.31008  -3.14866  -70.48110 1.000 71.86806  ? 188 SER B CA  1 
ATOM   5232 C  C   . SER B 1 188 ? 25.05462  -4.56335  -69.97211 1.000 76.23083  ? 188 SER B C   1 
ATOM   5233 O  O   . SER B 1 188 ? 24.97858  -4.77832  -68.75857 1.000 80.93353  ? 188 SER B O   1 
ATOM   5234 C  CB  . SER B 1 188 ? 23.98694  -2.40421  -70.66451 1.000 67.82471  ? 188 SER B CB  1 
ATOM   5235 O  OG  . SER B 1 188 ? 24.20158  -1.01790  -70.87559 1.000 87.69204  ? 188 SER B OG  1 
ATOM   5236 N  N   . ASN B 1 189 ? 24.91085  -5.53830  -70.86400 1.000 70.36589  ? 189 ASN B N   1 
ATOM   5237 C  CA  . ASN B 1 189 ? 24.66749  -6.90162  -70.41904 1.000 75.28554  ? 189 ASN B CA  1 
ATOM   5238 C  C   . ASN B 1 189 ? 25.94650  -7.72037  -70.26086 1.000 75.61333  ? 189 ASN B C   1 
ATOM   5239 O  O   . ASN B 1 189 ? 25.85812  -8.92360  -69.98966 1.000 92.99495  ? 189 ASN B O   1 
ATOM   5240 C  CB  . ASN B 1 189 ? 23.66443  -7.62864  -71.34514 1.000 72.75129  ? 189 ASN B CB  1 
ATOM   5241 C  CG  . ASN B 1 189 ? 22.60855  -8.36215  -70.53576 1.000 83.12840  ? 189 ASN B CG  1 
ATOM   5242 O  OD1 . ASN B 1 189 ? 22.94169  -9.34561  -69.86556 1.000 91.25230  ? 189 ASN B OD1 1 
ATOM   5243 N  ND2 . ASN B 1 189 ? 21.31570  -7.89555  -70.59836 1.000 98.03158  ? 189 ASN B ND2 1 
ATOM   5244 N  N   . ILE B 1 190 ? 27.12580  -7.11022  -70.41891 1.000 62.51458  ? 190 ILE B N   1 
ATOM   5245 C  CA  . ILE B 1 190 ? 28.38882  -7.77327  -70.11302 1.000 64.66017  ? 190 ILE B CA  1 
ATOM   5246 C  C   . ILE B 1 190 ? 29.27442  -6.96930  -69.17138 1.000 68.86565  ? 190 ILE B C   1 
ATOM   5247 O  O   . ILE B 1 190 ? 30.38101  -7.41433  -68.85561 1.000 62.91579  ? 190 ILE B O   1 
ATOM   5248 C  CB  . ILE B 1 190 ? 29.17720  -8.12784  -71.39125 1.000 55.28839  ? 190 ILE B CB  1 
ATOM   5249 C  CG1 . ILE B 1 190 ? 29.85916  -6.89093  -71.97605 1.000 66.86065  ? 190 ILE B CG1 1 
ATOM   5250 C  CG2 . ILE B 1 190 ? 28.26920  -8.76117  -72.43041 1.000 73.00393  ? 190 ILE B CG2 1 
ATOM   5251 C  CD1 . ILE B 1 190 ? 30.68686  -7.18710  -73.21114 1.000 69.43397  ? 190 ILE B CD1 1 
ATOM   5252 N  N   . SER B 1 191 ? 28.83694  -5.80034  -68.70375 1.000 74.71563  ? 191 SER B N   1 
ATOM   5253 C  CA  . SER B 1 191 ? 29.64934  -4.97648  -67.81434 1.000 66.07201  ? 191 SER B CA  1 
ATOM   5254 C  C   . SER B 1 191 ? 29.13674  -5.05636  -66.37843 1.000 63.06602  ? 191 SER B C   1 
ATOM   5255 O  O   . SER B 1 191 ? 27.98519  -5.41861  -66.12332 1.000 66.15916  ? 191 SER B O   1 
ATOM   5256 C  CB  . SER B 1 191 ? 29.67884  -3.52157  -68.28477 1.000 69.39663  ? 191 SER B CB  1 
ATOM   5257 O  OG  . SER B 1 191 ? 30.50953  -2.73149  -67.44992 1.000 73.78619  ? 191 SER B OG  1 
ATOM   5258 N  N   . LEU B 1 192 ? 30.01502  -4.70394  -65.43695 1.000 53.48704  ? 192 LEU B N   1 
ATOM   5259 C  CA  . LEU B 1 192 ? 29.73452  -4.82701  -64.01165 1.000 60.11660  ? 192 LEU B CA  1 
ATOM   5260 C  C   . LEU B 1 192 ? 29.25029  -3.53563  -63.35911 1.000 61.43207  ? 192 LEU B C   1 
ATOM   5261 O  O   . LEU B 1 192 ? 28.76491  -3.58368  -62.22356 1.000 48.40156  ? 192 LEU B O   1 
ATOM   5262 C  CB  . LEU B 1 192 ? 30.98331  -5.32641  -63.26993 1.000 56.25648  ? 192 LEU B CB  1 
ATOM   5263 C  CG  . LEU B 1 192 ? 31.17170  -6.84124  -63.14979 1.000 53.93192  ? 192 LEU B CG  1 
ATOM   5264 C  CD1 . LEU B 1 192 ? 31.33794  -7.49940  -64.50855 1.000 67.89867  ? 192 LEU B CD1 1 
ATOM   5265 C  CD2 . LEU B 1 192 ? 32.36219  -7.15125  -62.25884 1.000 48.67020  ? 192 LEU B CD2 1 
ATOM   5266 N  N   . LEU B 1 193 ? 29.36730  -2.38948  -64.03236 1.000 63.52068  ? 193 LEU B N   1 
ATOM   5267 C  CA  . LEU B 1 193 ? 28.93123  -1.11183  -63.48010 1.000 66.05725  ? 193 LEU B CA  1 
ATOM   5268 C  C   . LEU B 1 193 ? 27.60120  -0.64500  -64.05960 1.000 57.90566  ? 193 LEU B C   1 
ATOM   5269 O  O   . LEU B 1 193 ? 27.24446  0.52816   -63.91013 1.000 66.03999  ? 193 LEU B O   1 
ATOM   5270 C  CB  . LEU B 1 193 ? 29.99781  -0.03456  -63.69371 1.000 64.44740  ? 193 LEU B CB  1 
ATOM   5271 C  CG  . LEU B 1 193 ? 30.97568  0.20529   -62.53865 1.000 62.57357  ? 193 LEU B CG  1 
ATOM   5272 C  CD1 . LEU B 1 193 ? 31.54544  1.61713   -62.59213 1.000 64.72695  ? 193 LEU B CD1 1 
ATOM   5273 C  CD2 . LEU B 1 193 ? 30.31889  -0.05950  -61.19015 1.000 63.70501  ? 193 LEU B CD2 1 
ATOM   5274 N  N   . THR B 1 194 ? 26.86297  -1.53712  -64.71949 1.000 53.44071  ? 194 THR B N   1 
ATOM   5275 C  CA  . THR B 1 194 ? 25.55605  -1.17674  -65.25523 1.000 65.95192  ? 194 THR B CA  1 
ATOM   5276 C  C   . THR B 1 194 ? 24.51065  -1.08111  -64.15483 1.000 75.06484  ? 194 THR B C   1 
ATOM   5277 O  O   . THR B 1 194 ? 23.54420  -0.31933  -64.28076 1.000 83.55479  ? 194 THR B O   1 
ATOM   5278 C  CB  . THR B 1 194 ? 25.14330  -2.19361  -66.31296 1.000 63.09576  ? 194 THR B CB  1 
ATOM   5279 O  OG1 . THR B 1 194 ? 24.74956  -3.41239  -65.67150 1.000 87.79450  ? 194 THR B OG1 1 
ATOM   5280 C  CG2 . THR B 1 194 ? 26.32729  -2.47297  -67.20754 1.000 74.81290  ? 194 THR B CG2 1 
ATOM   5281 N  N   . THR B 1 195 ? 24.69732  -1.83995  -63.08033 1.000 72.31015  ? 195 THR B N   1 
ATOM   5282 C  CA  . THR B 1 195 ? 23.90985  -1.73650  -61.86527 1.000 64.65035  ? 195 THR B CA  1 
ATOM   5283 C  C   . THR B 1 195 ? 24.88229  -1.65607  -60.70181 1.000 68.38460  ? 195 THR B C   1 
ATOM   5284 O  O   . THR B 1 195 ? 26.01034  -2.14852  -60.79204 1.000 74.76471  ? 195 THR B O   1 
ATOM   5285 C  CB  . THR B 1 195 ? 22.96330  -2.93744  -61.68412 1.000 71.51923  ? 195 THR B CB  1 
ATOM   5286 O  OG1 . THR B 1 195 ? 23.72784  -4.14979  -61.64393 1.000 81.46806  ? 195 THR B OG1 1 
ATOM   5287 C  CG2 . THR B 1 195 ? 21.96500  -3.01050  -62.83330 1.000 61.98126  ? 195 THR B CG2 1 
ATOM   5288 N  N   . ASP B 1 196 ? 24.45379  -1.00406  -59.62358 1.000 64.44500  ? 196 ASP B N   1 
ATOM   5289 C  CA  . ASP B 1 196 ? 25.30612  -0.87867  -58.44888 1.000 55.58003  ? 196 ASP B CA  1 
ATOM   5290 C  C   . ASP B 1 196 ? 25.68633  -2.27865  -57.98467 1.000 66.19081  ? 196 ASP B C   1 
ATOM   5291 O  O   . ASP B 1 196 ? 24.83213  -3.02831  -57.49418 1.000 78.19534  ? 196 ASP B O   1 
ATOM   5292 C  CB  . ASP B 1 196 ? 24.59874  -0.08957  -57.34454 1.000 74.28859  ? 196 ASP B CB  1 
ATOM   5293 C  CG  . ASP B 1 196 ? 25.52058  0.26547   -56.18619 1.000 85.94699  ? 196 ASP B CG  1 
ATOM   5294 O  OD1 . ASP B 1 196 ? 26.65688  -0.25219  -56.13633 1.000 82.36856  ? 196 ASP B OD1 1 
ATOM   5295 O  OD2 . ASP B 1 196 ? 25.10562  1.06991   -55.32287 1.000 75.85477  ? 196 ASP B OD2 1 
ATOM   5296 N  N   . PRO B 1 197 ? 26.95283  -2.67055  -58.14268 1.000 67.87386  ? 197 PRO B N   1 
ATOM   5297 C  CA  . PRO B 1 197 ? 27.33585  -4.04600  -57.79242 1.000 64.92811  ? 197 PRO B CA  1 
ATOM   5298 C  C   . PRO B 1 197 ? 27.09211  -4.37925  -56.33332 1.000 65.78721  ? 197 PRO B C   1 
ATOM   5299 O  O   . PRO B 1 197 ? 26.86795  -5.54941  -56.00023 1.000 71.43054  ? 197 PRO B O   1 
ATOM   5300 C  CB  . PRO B 1 197 ? 28.82814  -4.09211  -58.14915 1.000 50.61570  ? 197 PRO B CB  1 
ATOM   5301 C  CG  . PRO B 1 197 ? 29.28301  -2.67600  -58.06246 1.000 56.62557  ? 197 PRO B CG  1 
ATOM   5302 C  CD  . PRO B 1 197 ? 28.11621  -1.84807  -58.52128 1.000 63.23896  ? 197 PRO B CD  1 
ATOM   5303 N  N   . LEU B 1 198 ? 27.11663  -3.38219  -55.45195 1.000 62.33876  ? 198 LEU B N   1 
ATOM   5304 C  CA  . LEU B 1 198 ? 26.95352  -3.63337  -54.02970 1.000 74.30509  ? 198 LEU B CA  1 
ATOM   5305 C  C   . LEU B 1 198 ? 25.49575  -3.80663  -53.61306 1.000 74.97102  ? 198 LEU B C   1 
ATOM   5306 O  O   . LEU B 1 198 ? 25.24794  -4.14497  -52.44235 1.000 72.84282  ? 198 LEU B O   1 
ATOM   5307 C  CB  . LEU B 1 198 ? 27.59390  -2.50018  -53.22269 1.000 64.21585  ? 198 LEU B CB  1 
ATOM   5308 C  CG  . LEU B 1 198 ? 29.06149  -2.17617  -53.52961 1.000 68.16905  ? 198 LEU B CG  1 
ATOM   5309 C  CD1 . LEU B 1 198 ? 29.66113  -1.30117  -52.43539 1.000 66.64913  ? 198 LEU B CD1 1 
ATOM   5310 C  CD2 . LEU B 1 198 ? 29.89517  -3.43740  -53.73177 1.000 76.29786  ? 198 LEU B CD2 1 
ATOM   5311 N  N   . VAL B 1 199 ? 24.53640  -3.57506  -54.50976 1.000 65.35917  ? 199 VAL B N   1 
ATOM   5312 C  CA  . VAL B 1 199 ? 23.12479  -3.76048  -54.20562 1.000 61.63580  ? 199 VAL B CA  1 
ATOM   5313 C  C   . VAL B 1 199 ? 22.52525  -4.93812  -54.96446 1.000 69.68031  ? 199 VAL B C   1 
ATOM   5314 O  O   . VAL B 1 199 ? 21.67177  -5.65254  -54.43143 1.000 83.59484  ? 199 VAL B O   1 
ATOM   5315 C  CB  . VAL B 1 199 ? 22.32774  -2.46906  -54.48803 1.000 53.14303  ? 199 VAL B CB  1 
ATOM   5316 C  CG1 . VAL B 1 199 ? 22.14973  -2.20829  -55.97801 1.000 76.16378  ? 199 VAL B CG1 1 
ATOM   5317 C  CG2 . VAL B 1 199 ? 20.96218  -2.49371  -53.79598 1.000 62.84158  ? 199 VAL B CG2 1 
ATOM   5318 N  N   . THR B 1 200 ? 22.97083  -5.17402  -56.20267 1.000 57.06723  ? 200 THR B N   1 
ATOM   5319 C  CA  . THR B 1 200 ? 22.39626  -6.26062  -56.98546 1.000 67.89846  ? 200 THR B CA  1 
ATOM   5320 C  C   . THR B 1 200 ? 23.11436  -7.58382  -56.76975 1.000 69.89142  ? 200 THR B C   1 
ATOM   5321 O  O   . THR B 1 200 ? 22.49367  -8.64365  -56.91343 1.000 69.40099  ? 200 THR B O   1 
ATOM   5322 C  CB  . THR B 1 200 ? 22.38907  -5.90953  -58.47238 1.000 73.69874  ? 200 THR B CB  1 
ATOM   5323 O  OG1 . THR B 1 200 ? 23.64828  -5.34038  -58.84456 1.000 70.87396  ? 200 THR B OG1 1 
ATOM   5324 C  CG2 . THR B 1 200 ? 21.26441  -4.92513  -58.77846 1.000 64.69948  ? 200 THR B CG2 1 
ATOM   5325 N  N   . TYR B 1 201 ? 24.39489  -7.55109  -56.40746 1.000 63.23372  ? 201 TYR B N   1 
ATOM   5326 C  CA  . TYR B 1 201 ? 25.17567  -8.75528  -56.12609 1.000 67.50333  ? 201 TYR B CA  1 
ATOM   5327 C  C   . TYR B 1 201 ? 25.82654  -8.58071  -54.75954 1.000 75.15923  ? 201 TYR B C   1 
ATOM   5328 O  O   . TYR B 1 201 ? 27.04868  -8.42002  -54.64869 1.000 75.57723  ? 201 TYR B O   1 
ATOM   5329 C  CB  . TYR B 1 201 ? 26.21799  -9.00096  -57.21801 1.000 57.47790  ? 201 TYR B CB  1 
ATOM   5330 C  CG  . TYR B 1 201 ? 25.65267  -9.01528  -58.62353 1.000 65.29673  ? 201 TYR B CG  1 
ATOM   5331 C  CD1 . TYR B 1 201 ? 24.47782  -9.69564  -58.91599 1.000 73.62015  ? 201 TYR B CD1 1 
ATOM   5332 C  CD2 . TYR B 1 201 ? 26.29088  -8.34227  -59.65692 1.000 62.75423  ? 201 TYR B CD2 1 
ATOM   5333 C  CE1 . TYR B 1 201 ? 23.95568  -9.70664  -60.19652 1.000 78.72251  ? 201 TYR B CE1 1 
ATOM   5334 C  CE2 . TYR B 1 201 ? 25.77523  -8.34756  -60.94123 1.000 62.26907  ? 201 TYR B CE2 1 
ATOM   5335 C  CZ  . TYR B 1 201 ? 24.60852  -9.03332  -61.20537 1.000 67.71593  ? 201 TYR B CZ  1 
ATOM   5336 O  OH  . TYR B 1 201 ? 24.08777  -9.04720  -62.47990 1.000 77.81316  ? 201 TYR B OH  1 
ATOM   5337 N  N   . PRO B 1 202 ? 25.02562  -8.60800  -53.68888 1.000 70.15054  ? 202 PRO B N   1 
ATOM   5338 C  CA  . PRO B 1 202 ? 25.52119  -8.11390  -52.39424 1.000 75.48252  ? 202 PRO B CA  1 
ATOM   5339 C  C   . PRO B 1 202 ? 26.51903  -9.03432  -51.70944 1.000 76.30643  ? 202 PRO B C   1 
ATOM   5340 O  O   . PRO B 1 202 ? 27.34692  -8.54852  -50.92862 1.000 69.15970  ? 202 PRO B O   1 
ATOM   5341 C  CB  . PRO B 1 202 ? 24.23704  -7.96024  -51.56265 1.000 64.17419  ? 202 PRO B CB  1 
ATOM   5342 C  CG  . PRO B 1 202 ? 23.10151  -8.02716  -52.56181 1.000 54.52673  ? 202 PRO B CG  1 
ATOM   5343 C  CD  . PRO B 1 202 ? 23.59370  -8.93536  -53.63569 1.000 62.38308  ? 202 PRO B CD  1 
ATOM   5344 N  N   . SER B 1 203 ? 26.47771  -10.33660 -51.96563 1.000 81.24522  ? 203 SER B N   1 
ATOM   5345 C  CA  . SER B 1 203 ? 27.35828  -11.26811 -51.27379 1.000 82.59375  ? 203 SER B CA  1 
ATOM   5346 C  C   . SER B 1 203 ? 28.66420  -11.44437 -52.03815 1.000 77.00983  ? 203 SER B C   1 
ATOM   5347 O  O   . SER B 1 203 ? 28.72803  -11.23916 -53.25356 1.000 94.36355  ? 203 SER B O   1 
ATOM   5348 C  CB  . SER B 1 203 ? 26.67230  -12.62179 -51.08505 1.000 84.09158  ? 203 SER B CB  1 
ATOM   5349 O  OG  . SER B 1 203 ? 27.61726  -13.64937 -50.84702 1.000 88.35171  ? 203 SER B OG  1 
ATOM   5350 N  N   . LEU B 1 204 ? 29.71736  -11.80916 -51.30142 1.000 68.90158  ? 204 LEU B N   1 
ATOM   5351 C  CA  . LEU B 1 204 ? 30.99913  -12.09588 -51.93638 1.000 64.87080  ? 204 LEU B CA  1 
ATOM   5352 C  C   . LEU B 1 204 ? 30.85746  -13.20504 -52.96893 1.000 80.26866  ? 204 LEU B C   1 
ATOM   5353 O  O   . LEU B 1 204 ? 31.49501  -13.16543 -54.02804 1.000 77.80425  ? 204 LEU B O   1 
ATOM   5354 C  CB  . LEU B 1 204 ? 32.03874  -12.47896 -50.88222 1.000 64.00837  ? 204 LEU B CB  1 
ATOM   5355 C  CG  . LEU B 1 204 ? 33.46610  -12.69676 -51.39230 1.000 60.48090  ? 204 LEU B CG  1 
ATOM   5356 C  CD1 . LEU B 1 204 ? 34.29920  -11.44396 -51.19545 1.000 59.89939  ? 204 LEU B CD1 1 
ATOM   5357 C  CD2 . LEU B 1 204 ? 34.12449  -13.89528 -50.72161 1.000 72.73054  ? 204 LEU B CD2 1 
ATOM   5358 N  N   . ASP B 1 205 ? 30.02612  -14.20662 -52.67302 1.000 75.09027  ? 205 ASP B N   1 
ATOM   5359 C  CA  . ASP B 1 205 ? 29.74063  -15.24943 -53.65156 1.000 75.21406  ? 205 ASP B CA  1 
ATOM   5360 C  C   . ASP B 1 205 ? 29.06600  -14.67214 -54.88955 1.000 79.00832  ? 205 ASP B C   1 
ATOM   5361 O  O   . ASP B 1 205 ? 29.40212  -15.04289 -56.02076 1.000 85.66257  ? 205 ASP B O   1 
ATOM   5362 C  CB  . ASP B 1 205 ? 28.85789  -16.32803 -53.02244 1.000 82.20998  ? 205 ASP B CB  1 
ATOM   5363 C  CG  . ASP B 1 205 ? 29.30335  -16.70485 -51.62161 1.000 99.58917  ? 205 ASP B CG  1 
ATOM   5364 O  OD1 . ASP B 1 205 ? 30.51339  -16.94160 -51.41897 1.000 98.61267  ? 205 ASP B OD1 1 
ATOM   5365 O  OD2 . ASP B 1 205 ? 28.44083  -16.75407 -50.71894 1.000 100.56789 ? 205 ASP B OD2 1 
ATOM   5366 N  N   . LYS B 1 206 ? 28.11106  -13.75883 -54.69413 1.000 68.96760  ? 206 LYS B N   1 
ATOM   5367 C  CA  . LYS B 1 206 ? 27.30878  -13.27767 -55.81460 1.000 64.34852  ? 206 LYS B CA  1 
ATOM   5368 C  C   . LYS B 1 206 ? 28.11466  -12.36322 -56.72941 1.000 64.75930  ? 206 LYS B C   1 
ATOM   5369 O  O   . LYS B 1 206 ? 28.02780  -12.47557 -57.95764 1.000 61.87897  ? 206 LYS B O   1 
ATOM   5370 C  CB  . LYS B 1 206 ? 26.05908  -12.55661 -55.30290 1.000 55.46830  ? 206 LYS B CB  1 
ATOM   5371 C  CG  . LYS B 1 206 ? 25.31362  -13.27243 -54.17925 1.000 71.95054  ? 206 LYS B CG  1 
ATOM   5372 C  CD  . LYS B 1 206 ? 25.15848  -14.76828 -54.42398 1.000 86.94104  ? 206 LYS B CD  1 
ATOM   5373 C  CE  . LYS B 1 206 ? 24.99630  -15.51587 -53.10618 1.000 95.92245  ? 206 LYS B CE  1 
ATOM   5374 N  NZ  . LYS B 1 206 ? 25.08633  -16.99205 -53.27561 1.000 78.61305  ? 206 LYS B NZ  1 
ATOM   5375 N  N   . VAL B 1 207 ? 28.89876  -11.44798 -56.15636 1.000 73.52200  ? 207 VAL B N   1 
ATOM   5376 C  CA  . VAL B 1 207 ? 29.66644  -10.52753 -56.98862 1.000 69.99961  ? 207 VAL B CA  1 
ATOM   5377 C  C   . VAL B 1 207 ? 30.80071  -11.26078 -57.69847 1.000 69.31247  ? 207 VAL B C   1 
ATOM   5378 O  O   . VAL B 1 207 ? 31.09038  -10.99078 -58.86838 1.000 80.95340  ? 207 VAL B O   1 
ATOM   5379 C  CB  . VAL B 1 207 ? 30.17534  -9.33373  -56.15735 1.000 55.58216  ? 207 VAL B CB  1 
ATOM   5380 C  CG1 . VAL B 1 207 ? 31.14517  -9.78105  -55.07129 1.000 64.04579  ? 207 VAL B CG1 1 
ATOM   5381 C  CG2 . VAL B 1 207 ? 30.81498  -8.29364  -57.06396 1.000 44.45729  ? 207 VAL B CG2 1 
ATOM   5382 N  N   . TRP B 1 208 ? 31.46509  -12.19427 -57.00936 1.000 66.50566  ? 208 TRP B N   1 
ATOM   5383 C  CA  . TRP B 1 208 ? 32.49714  -12.98853 -57.66768 1.000 62.70694  ? 208 TRP B CA  1 
ATOM   5384 C  C   . TRP B 1 208 ? 31.90428  -13.89783 -58.73228 1.000 62.06423  ? 208 TRP B C   1 
ATOM   5385 O  O   . TRP B 1 208 ? 32.60278  -14.27693 -59.67944 1.000 64.41708  ? 208 TRP B O   1 
ATOM   5386 C  CB  . TRP B 1 208 ? 33.28515  -13.80264 -56.64270 1.000 54.26962  ? 208 TRP B CB  1 
ATOM   5387 C  CG  . TRP B 1 208 ? 34.51639  -13.10501 -56.13739 1.000 60.92488  ? 208 TRP B CG  1 
ATOM   5388 C  CD1 . TRP B 1 208 ? 34.62293  -12.32959 -55.01780 1.000 66.00686  ? 208 TRP B CD1 1 
ATOM   5389 C  CD2 . TRP B 1 208 ? 35.81619  -13.11905 -56.74013 1.000 60.08175  ? 208 TRP B CD2 1 
ATOM   5390 N  NE1 . TRP B 1 208 ? 35.91046  -11.86407 -54.88509 1.000 68.74940  ? 208 TRP B NE1 1 
ATOM   5391 C  CE2 . TRP B 1 208 ? 36.66197  -12.33469 -55.93003 1.000 63.56792  ? 208 TRP B CE2 1 
ATOM   5392 C  CE3 . TRP B 1 208 ? 36.34681  -13.72036 -57.88559 1.000 65.32476  ? 208 TRP B CE3 1 
ATOM   5393 C  CZ2 . TRP B 1 208 ? 38.00954  -12.13737 -56.22937 1.000 67.30558  ? 208 TRP B CZ2 1 
ATOM   5394 C  CZ3 . TRP B 1 208 ? 37.68272  -13.52285 -58.18020 1.000 61.27641  ? 208 TRP B CZ3 1 
ATOM   5395 C  CH2 . TRP B 1 208 ? 38.49886  -12.73886 -57.35621 1.000 59.39499  ? 208 TRP B CH2 1 
ATOM   5396 N  N   . GLY B 1 209 ? 30.63088  -14.26634 -58.58904 1.000 59.12783  ? 209 GLY B N   1 
ATOM   5397 C  CA  . GLY B 1 209 ? 29.96504  -15.00096 -59.65120 1.000 60.95279  ? 209 GLY B CA  1 
ATOM   5398 C  C   . GLY B 1 209 ? 29.81580  -14.17183 -60.91150 1.000 54.87970  ? 209 GLY B C   1 
ATOM   5399 O  O   . GLY B 1 209 ? 30.06398  -14.65106 -62.02110 1.000 55.57008  ? 209 GLY B O   1 
ATOM   5400 N  N   . ARG B 1 210 ? 29.41069  -12.90997 -60.75377 1.000 58.09784  ? 210 ARG B N   1 
ATOM   5401 C  CA  . ARG B 1 210 ? 29.32977  -12.00500 -61.89456 1.000 53.41895  ? 210 ARG B CA  1 
ATOM   5402 C  C   . ARG B 1 210 ? 30.71372  -11.69625 -62.44968 1.000 58.17577  ? 210 ARG B C   1 
ATOM   5403 O  O   . ARG B 1 210 ? 30.88352  -11.55356 -63.66654 1.000 61.26369  ? 210 ARG B O   1 
ATOM   5404 C  CB  . ARG B 1 210 ? 28.61441  -10.71715 -61.48827 1.000 52.92780  ? 210 ARG B CB  1 
ATOM   5405 C  CG  . ARG B 1 210 ? 28.45077  -9.70383  -62.61215 1.000 65.72388  ? 210 ARG B CG  1 
ATOM   5406 C  CD  . ARG B 1 210 ? 27.40149  -10.15598 -63.61211 1.000 62.16441  ? 210 ARG B CD  1 
ATOM   5407 N  NE  . ARG B 1 210 ? 27.22034  -9.19863  -64.69656 1.000 63.73518  ? 210 ARG B NE  1 
ATOM   5408 C  CZ  . ARG B 1 210 ? 27.83453  -9.27030  -65.86933 1.000 76.76702  ? 210 ARG B CZ  1 
ATOM   5409 N  NH1 . ARG B 1 210 ? 28.68482  -10.24523 -66.14507 1.000 65.88626  ? 210 ARG B NH1 1 
ATOM   5410 N  NH2 . ARG B 1 210 ? 27.58751  -8.34203  -66.78960 1.000 73.01621  ? 210 ARG B NH2 1 
ATOM   5411 N  N   . PHE B 1 211 ? 31.71216  -11.58034 -61.57077 1.000 49.22796  ? 211 PHE B N   1 
ATOM   5412 C  CA  . PHE B 1 211 ? 33.07413  -11.32674 -62.02605 1.000 61.39578  ? 211 PHE B CA  1 
ATOM   5413 C  C   . PHE B 1 211 ? 33.59548  -12.48404 -62.87042 1.000 61.28795  ? 211 PHE B C   1 
ATOM   5414 O  O   . PHE B 1 211 ? 34.25070  -12.26770 -63.89628 1.000 61.09416  ? 211 PHE B O   1 
ATOM   5415 C  CB  . PHE B 1 211 ? 33.98440  -11.07007 -60.82501 1.000 56.56513  ? 211 PHE B CB  1 
ATOM   5416 C  CG  . PHE B 1 211 ? 35.35518  -10.58697 -61.19657 1.000 57.82715  ? 211 PHE B CG  1 
ATOM   5417 C  CD1 . PHE B 1 211 ? 35.51508  -9.47859  -62.01087 1.000 60.44058  ? 211 PHE B CD1 1 
ATOM   5418 C  CD2 . PHE B 1 211 ? 36.48401  -11.23629 -60.72646 1.000 62.42656  ? 211 PHE B CD2 1 
ATOM   5419 C  CE1 . PHE B 1 211 ? 36.77565  -9.03116  -62.35348 1.000 61.04421  ? 211 PHE B CE1 1 
ATOM   5420 C  CE2 . PHE B 1 211 ? 37.74657  -10.79323 -61.06558 1.000 60.30926  ? 211 PHE B CE2 1 
ATOM   5421 C  CZ  . PHE B 1 211 ? 37.89189  -9.68957  -61.87862 1.000 59.91891  ? 211 PHE B CZ  1 
ATOM   5422 N  N   . ASP B 1 212 ? 33.31266  -13.72205 -62.45558 1.000 52.56383  ? 212 ASP B N   1 
ATOM   5423 C  CA  . ASP B 1 212 ? 33.70286  -14.87785 -63.25720 1.000 51.67104  ? 212 ASP B CA  1 
ATOM   5424 C  C   . ASP B 1 212 ? 32.88790  -14.96147 -64.54133 1.000 53.51748  ? 212 ASP B C   1 
ATOM   5425 O  O   . ASP B 1 212 ? 33.41613  -15.33488 -65.59548 1.000 50.79630  ? 212 ASP B O   1 
ATOM   5426 C  CB  . ASP B 1 212 ? 33.55198  -16.16199 -62.44155 1.000 62.82080  ? 212 ASP B CB  1 
ATOM   5427 C  CG  . ASP B 1 212 ? 34.66565  -16.34261 -61.42669 1.000 67.27003  ? 212 ASP B CG  1 
ATOM   5428 O  OD1 . ASP B 1 212 ? 35.79387  -15.87629 -61.69322 1.000 75.26791  ? 212 ASP B OD1 1 
ATOM   5429 O  OD2 . ASP B 1 212 ? 34.41517  -16.95053 -60.36395 1.000 55.97745  ? 212 ASP B OD2 1 
ATOM   5430 N  N   . LYS B 1 213 ? 31.59876  -14.62217 -64.47229 1.000 58.14872  ? 213 LYS B N   1 
ATOM   5431 C  CA  . LYS B 1 213 ? 30.77084  -14.62157 -65.67339 1.000 56.16788  ? 213 LYS B CA  1 
ATOM   5432 C  C   . LYS B 1 213 ? 31.30246  -13.63665 -66.70334 1.000 56.78592  ? 213 LYS B C   1 
ATOM   5433 O  O   . LYS B 1 213 ? 31.25812  -13.90499 -67.90765 1.000 66.35368  ? 213 LYS B O   1 
ATOM   5434 C  CB  . LYS B 1 213 ? 29.32242  -14.28837 -65.31444 1.000 56.61813  ? 213 LYS B CB  1 
ATOM   5435 C  CG  . LYS B 1 213 ? 28.39424  -14.13578 -66.51368 1.000 57.41349  ? 213 LYS B CG  1 
ATOM   5436 C  CD  . LYS B 1 213 ? 28.19927  -15.45601 -67.24514 1.000 71.83341  ? 213 LYS B CD  1 
ATOM   5437 C  CE  . LYS B 1 213 ? 27.33889  -16.42349 -66.44204 1.000 78.16223  ? 213 LYS B CE  1 
ATOM   5438 N  NZ  . LYS B 1 213 ? 27.20406  -17.75361 -67.10871 1.000 49.17381  ? 213 LYS B NZ  1 
ATOM   5439 N  N   . HIS B 1 214 ? 31.79836  -12.48623 -66.24387 1.000 65.26819  ? 214 HIS B N   1 
ATOM   5440 C  CA  . HIS B 1 214 ? 32.35874  -11.48124 -67.14223 1.000 54.82747  ? 214 HIS B CA  1 
ATOM   5441 C  C   . HIS B 1 214 ? 33.41813  -12.08025 -68.06121 1.000 61.11925  ? 214 HIS B C   1 
ATOM   5442 O  O   . HIS B 1 214 ? 33.41101  -11.84448 -69.27562 1.000 73.41864  ? 214 HIS B O   1 
ATOM   5443 C  CB  . HIS B 1 214 ? 32.93618  -10.32853 -66.31548 1.000 54.05408  ? 214 HIS B CB  1 
ATOM   5444 C  CG  . HIS B 1 214 ? 33.64857  -9.29008  -67.12525 1.000 59.50156  ? 214 HIS B CG  1 
ATOM   5445 N  ND1 . HIS B 1 214 ? 32.98888  -8.27449  -67.78346 1.000 59.44226  ? 214 HIS B ND1 1 
ATOM   5446 C  CD2 . HIS B 1 214 ? 34.96696  -9.10075  -67.36830 1.000 54.15326  ? 214 HIS B CD2 1 
ATOM   5447 C  CE1 . HIS B 1 214 ? 33.86933  -7.50901  -68.40348 1.000 53.25954  ? 214 HIS B CE1 1 
ATOM   5448 N  NE2 . HIS B 1 214 ? 35.07697  -7.98864  -68.16741 1.000 53.14025  ? 214 HIS B NE2 1 
ATOM   5449 N  N   . PHE B 1 215 ? 34.33363  -12.87090 -67.49702 1.000 66.67754  ? 215 PHE B N   1 
ATOM   5450 C  CA  . PHE B 1 215 ? 35.43263  -13.41354 -68.29086 1.000 66.87485  ? 215 PHE B CA  1 
ATOM   5451 C  C   . PHE B 1 215 ? 34.96599  -14.52504 -69.22495 1.000 68.94002  ? 215 PHE B C   1 
ATOM   5452 O  O   . PHE B 1 215 ? 35.47047  -14.64678 -70.34795 1.000 71.64559  ? 215 PHE B O   1 
ATOM   5453 C  CB  . PHE B 1 215 ? 36.54706  -13.90443 -67.36952 1.000 56.41883  ? 215 PHE B CB  1 
ATOM   5454 C  CG  . PHE B 1 215 ? 37.28457  -12.79725 -66.68032 1.000 70.91065  ? 215 PHE B CG  1 
ATOM   5455 C  CD1 . PHE B 1 215 ? 38.33647  -12.15438 -67.30889 1.000 72.57168  ? 215 PHE B CD1 1 
ATOM   5456 C  CD2 . PHE B 1 215 ? 36.91799  -12.38734 -65.41090 1.000 80.83022  ? 215 PHE B CD2 1 
ATOM   5457 C  CE1 . PHE B 1 215 ? 39.01623  -11.12832 -66.68008 1.000 70.04815  ? 215 PHE B CE1 1 
ATOM   5458 C  CE2 . PHE B 1 215 ? 37.59309  -11.36298 -64.77747 1.000 74.93165  ? 215 PHE B CE2 1 
ATOM   5459 C  CZ  . PHE B 1 215 ? 38.64427  -10.73239 -65.41227 1.000 71.17982  ? 215 PHE B CZ  1 
ATOM   5460 N  N   . SER B 1 216 ? 34.00973  -15.34816 -68.78686 1.000 69.22850  ? 216 SER B N   1 
ATOM   5461 C  CA  . SER B 1 216 ? 33.50238  -16.39511 -69.66959 1.000 71.49330  ? 216 SER B CA  1 
ATOM   5462 C  C   . SER B 1 216 ? 32.71187  -15.80750 -70.83194 1.000 72.25615  ? 216 SER B C   1 
ATOM   5463 O  O   . SER B 1 216 ? 32.62893  -16.42528 -71.89827 1.000 79.51203  ? 216 SER B O   1 
ATOM   5464 C  CB  . SER B 1 216 ? 32.63848  -17.38677 -68.88769 1.000 60.11502  ? 216 SER B CB  1 
ATOM   5465 O  OG  . SER B 1 216 ? 31.31501  -16.90665 -68.72295 1.000 63.91874  ? 216 SER B OG  1 
ATOM   5466 N  N   . GLN B 1 217 ? 32.12305  -14.62385 -70.64325 1.000 69.24943  ? 217 GLN B N   1 
ATOM   5467 C  CA  . GLN B 1 217 ? 31.41724  -13.96459 -71.73581 1.000 62.90466  ? 217 GLN B CA  1 
ATOM   5468 C  C   . GLN B 1 217 ? 32.37475  -13.59292 -72.85948 1.000 58.32707  ? 217 GLN B C   1 
ATOM   5469 O  O   . GLN B 1 217 ? 32.01605  -13.65897 -74.04164 1.000 70.82016  ? 217 GLN B O   1 
ATOM   5470 C  CB  . GLN B 1 217 ? 30.69006  -12.71839 -71.22453 1.000 48.67366  ? 217 GLN B CB  1 
ATOM   5471 C  CG  . GLN B 1 217 ? 29.55870  -12.98473 -70.24452 1.000 60.91883  ? 217 GLN B CG  1 
ATOM   5472 C  CD  . GLN B 1 217 ? 28.92173  -11.70616 -69.71917 1.000 64.20521  ? 217 GLN B CD  1 
ATOM   5473 O  OE1 . GLN B 1 217 ? 29.47120  -11.04499 -68.83912 1.000 68.76295  ? 217 GLN B OE1 1 
ATOM   5474 N  NE2 . GLN B 1 217 ? 27.75665  -11.35582 -70.25544 1.000 53.11615  ? 217 GLN B NE2 1 
ATOM   5475 N  N   . LEU B 1 218 ? 33.59964  -13.20330 -72.50944 1.000 53.23478  ? 218 LEU B N   1 
ATOM   5476 C  CA  . LEU B 1 218 ? 34.53600  -12.62222 -73.45938 1.000 61.33850  ? 218 LEU B CA  1 
ATOM   5477 C  C   . LEU B 1 218 ? 35.63993  -13.57451 -73.90395 1.000 64.97476  ? 218 LEU B C   1 
ATOM   5478 O  O   . LEU B 1 218 ? 36.42913  -13.20593 -74.78069 1.000 57.75819  ? 218 LEU B O   1 
ATOM   5479 C  CB  . LEU B 1 218 ? 35.17664  -11.36862 -72.85118 1.000 61.83794  ? 218 LEU B CB  1 
ATOM   5480 C  CG  . LEU B 1 218 ? 34.26452  -10.20790 -72.44849 1.000 66.88290  ? 218 LEU B CG  1 
ATOM   5481 C  CD1 . LEU B 1 218 ? 35.08285  -9.09802  -71.80047 1.000 46.45890  ? 218 LEU B CD1 1 
ATOM   5482 C  CD2 . LEU B 1 218 ? 33.48093  -9.67628  -73.64315 1.000 62.19982  ? 218 LEU B CD2 1 
ATOM   5483 N  N   . ARG B 1 219 ? 35.71929  -14.77873 -73.33057 1.000 72.12280  ? 219 ARG B N   1 
ATOM   5484 C  CA  . ARG B 1 219 ? 36.87050  -15.64035 -73.58861 1.000 71.33589  ? 219 ARG B CA  1 
ATOM   5485 C  C   . ARG B 1 219 ? 36.95290  -16.03985 -75.05664 1.000 75.03127  ? 219 ARG B C   1 
ATOM   5486 O  O   . ARG B 1 219 ? 38.04711  -16.10532 -75.62878 1.000 73.14599  ? 219 ARG B O   1 
ATOM   5487 C  CB  . ARG B 1 219 ? 36.81455  -16.88533 -72.70520 1.000 63.16516  ? 219 ARG B CB  1 
ATOM   5488 C  CG  . ARG B 1 219 ? 38.14567  -17.61832 -72.61068 1.000 61.61965  ? 219 ARG B CG  1 
ATOM   5489 C  CD  . ARG B 1 219 ? 37.96094  -19.12713 -72.59087 1.000 79.79403  ? 219 ARG B CD  1 
ATOM   5490 N  NE  . ARG B 1 219 ? 39.16426  -19.81534 -72.13781 1.000 79.87713  ? 219 ARG B NE  1 
ATOM   5491 C  CZ  . ARG B 1 219 ? 39.27651  -20.43697 -70.97190 1.000 83.61509  ? 219 ARG B CZ  1 
ATOM   5492 N  NH1 . ARG B 1 219 ? 38.26052  -20.51172 -70.12765 1.000 79.98169  ? 219 ARG B NH1 1 
ATOM   5493 N  NH2 . ARG B 1 219 ? 40.43569  -21.00237 -70.64719 1.000 88.61249  ? 219 ARG B NH2 1 
ATOM   5494 N  N   . GLY B 1 220 ? 35.80904  -16.30997 -75.68367 1.000 68.25827  ? 220 GLY B N   1 
ATOM   5495 C  CA  . GLY B 1 220 ? 35.79879  -16.72981 -77.07401 1.000 67.13958  ? 220 GLY B CA  1 
ATOM   5496 C  C   . GLY B 1 220 ? 36.23818  -15.66830 -78.06083 1.000 67.40775  ? 220 GLY B C   1 
ATOM   5497 O  O   . GLY B 1 220 ? 36.51304  -16.00509 -79.21820 1.000 73.85205  ? 220 GLY B O   1 
ATOM   5498 N  N   . ILE B 1 221 ? 36.31541  -14.40864 -77.63833 1.000 68.25865  ? 221 ILE B N   1 
ATOM   5499 C  CA  . ILE B 1 221 ? 36.67128  -13.32290 -78.54130 1.000 56.38697  ? 221 ILE B CA  1 
ATOM   5500 C  C   . ILE B 1 221 ? 37.96939  -12.62361 -78.15575 1.000 60.57421  ? 221 ILE B C   1 
ATOM   5501 O  O   . ILE B 1 221 ? 38.62694  -12.04402 -79.03551 1.000 68.63861  ? 221 ILE B O   1 
ATOM   5502 C  CB  . ILE B 1 221 ? 35.52265  -12.29628 -78.64676 1.000 66.39286  ? 221 ILE B CB  1 
ATOM   5503 C  CG1 . ILE B 1 221 ? 35.66351  -11.44436 -79.91208 1.000 67.27219  ? 221 ILE B CG1 1 
ATOM   5504 C  CG2 . ILE B 1 221 ? 35.45491  -11.42234 -77.40011 1.000 67.19775  ? 221 ILE B CG2 1 
ATOM   5505 C  CD1 . ILE B 1 221 ? 34.47497  -10.54183 -80.17426 1.000 62.17235  ? 221 ILE B CD1 1 
ATOM   5506 N  N   . ILE B 1 222 ? 38.38943  -12.66373 -76.88777 1.000 55.54784  ? 222 ILE B N   1 
ATOM   5507 C  CA  . ILE B 1 222 ? 39.64552  -12.02749 -76.49804 1.000 54.82519  ? 222 ILE B CA  1 
ATOM   5508 C  C   . ILE B 1 222 ? 40.84510  -12.93118 -76.74188 1.000 64.49429  ? 222 ILE B C   1 
ATOM   5509 O  O   . ILE B 1 222 ? 41.98489  -12.44403 -76.76100 1.000 68.47837  ? 222 ILE B O   1 
ATOM   5510 C  CB  . ILE B 1 222 ? 39.56619  -11.57978 -75.02281 1.000 62.03884  ? 222 ILE B CB  1 
ATOM   5511 C  CG1 . ILE B 1 222 ? 38.33700  -10.69696 -74.81007 1.000 78.42522  ? 222 ILE B CG1 1 
ATOM   5512 C  CG2 . ILE B 1 222 ? 40.80555  -10.79616 -74.60668 1.000 71.70743  ? 222 ILE B CG2 1 
ATOM   5513 C  CD1 . ILE B 1 222 ? 38.36129  -9.92659  -73.50789 1.000 81.51130  ? 222 ILE B CD1 1 
ATOM   5514 N  N   . TYR B 1 223 ? 40.62983  -14.22602 -76.97176 1.000 73.80281  ? 223 TYR B N   1 
ATOM   5515 C  CA  . TYR B 1 223 ? 41.72752  -15.14892 -77.22421 1.000 76.13622  ? 223 TYR B CA  1 
ATOM   5516 C  C   . TYR B 1 223 ? 41.94095  -15.45078 -78.70232 1.000 81.08057  ? 223 TYR B C   1 
ATOM   5517 O  O   . TYR B 1 223 ? 42.80369  -16.26978 -79.02991 1.000 79.63520  ? 223 TYR B O   1 
ATOM   5518 C  CB  . TYR B 1 223 ? 41.50978  -16.45293 -76.45475 1.000 69.02201  ? 223 TYR B CB  1 
ATOM   5519 C  CG  . TYR B 1 223 ? 41.96937  -16.37318 -75.01885 1.000 68.27337  ? 223 TYR B CG  1 
ATOM   5520 C  CD1 . TYR B 1 223 ? 43.29330  -16.61864 -74.67657 1.000 70.41812  ? 223 TYR B CD1 1 
ATOM   5521 C  CD2 . TYR B 1 223 ? 41.08206  -16.04085 -74.00719 1.000 66.52989  ? 223 TYR B CD2 1 
ATOM   5522 C  CE1 . TYR B 1 223 ? 43.71645  -16.54133 -73.36371 1.000 75.52826  ? 223 TYR B CE1 1 
ATOM   5523 C  CE2 . TYR B 1 223 ? 41.49416  -15.96062 -72.69480 1.000 72.32902  ? 223 TYR B CE2 1 
ATOM   5524 C  CZ  . TYR B 1 223 ? 42.81155  -16.21068 -72.37626 1.000 72.18602  ? 223 TYR B CZ  1 
ATOM   5525 O  OH  . TYR B 1 223 ? 43.22201  -16.12932 -71.06532 1.000 82.72342  ? 223 TYR B OH  1 
ATOM   5526 N  N   . HIS B 1 224 ? 41.19222  -14.81383 -79.60006 1.000 73.36102  ? 224 HIS B N   1 
ATOM   5527 C  CA  . HIS B 1 224 ? 41.51487  -14.89826 -81.01878 1.000 73.25103  ? 224 HIS B CA  1 
ATOM   5528 C  C   . HIS B 1 224 ? 42.79349  -14.11287 -81.27434 1.000 75.14325  ? 224 HIS B C   1 
ATOM   5529 O  O   . HIS B 1 224 ? 42.89337  -12.94465 -80.89113 1.000 73.94978  ? 224 HIS B O   1 
ATOM   5530 C  CB  . HIS B 1 224 ? 40.36811  -14.34754 -81.86736 1.000 67.61489  ? 224 HIS B CB  1 
ATOM   5531 C  CG  . HIS B 1 224 ? 40.55050  -14.55309 -83.34015 1.000 69.28069  ? 224 HIS B CG  1 
ATOM   5532 N  ND1 . HIS B 1 224 ? 40.04735  -13.68012 -84.28019 1.000 72.62455  ? 224 HIS B ND1 1 
ATOM   5533 C  CD2 . HIS B 1 224 ? 41.16889  -15.53714 -84.03518 1.000 68.92059  ? 224 HIS B CD2 1 
ATOM   5534 C  CE1 . HIS B 1 224 ? 40.35239  -14.11350 -85.49031 1.000 67.81466  ? 224 HIS B CE1 1 
ATOM   5535 N  NE2 . HIS B 1 224 ? 41.03287  -15.23891 -85.36957 1.000 74.11453  ? 224 HIS B NE2 1 
ATOM   5536 N  N   . THR B 1 225 ? 43.76792  -14.75437 -81.91867 1.000 68.87666  ? 225 THR B N   1 
ATOM   5537 C  CA  . THR B 1 225 ? 45.11206  -14.18556 -82.01990 1.000 62.15579  ? 225 THR B CA  1 
ATOM   5538 C  C   . THR B 1 225 ? 45.14470  -12.76694 -82.57930 1.000 62.54126  ? 225 THR B C   1 
ATOM   5539 O  O   . THR B 1 225 ? 45.84738  -11.92283 -82.00075 1.000 67.02959  ? 225 THR B O   1 
ATOM   5540 C  CB  . THR B 1 225 ? 46.00373  -15.12311 -82.84629 1.000 63.01269  ? 225 THR B CB  1 
ATOM   5541 O  OG1 . THR B 1 225 ? 46.08345  -16.40027 -82.20154 1.000 68.02380  ? 225 THR B OG1 1 
ATOM   5542 C  CG2 . THR B 1 225 ? 47.40301  -14.54453 -82.97759 1.000 64.11131  ? 225 THR B CG2 1 
ATOM   5543 N  N   . PRO B 1 226 ? 44.44018  -12.42777 -83.66676 1.000 75.14070  ? 226 PRO B N   1 
ATOM   5544 C  CA  . PRO B 1 226 ? 44.43283  -11.01297 -84.08919 1.000 73.72731  ? 226 PRO B CA  1 
ATOM   5545 C  C   . PRO B 1 226 ? 43.78174  -10.09019 -83.07144 1.000 70.85443  ? 226 PRO B C   1 
ATOM   5546 O  O   . PRO B 1 226 ? 44.31556  -9.01115  -82.78230 1.000 73.19469  ? 226 PRO B O   1 
ATOM   5547 C  CB  . PRO B 1 226 ? 43.65848  -11.04787 -85.41625 1.000 65.96154  ? 226 PRO B CB  1 
ATOM   5548 C  CG  . PRO B 1 226 ? 43.71639  -12.46545 -85.86894 1.000 80.56132  ? 226 PRO B CG  1 
ATOM   5549 C  CD  . PRO B 1 226 ? 43.70605  -13.27896 -84.62059 1.000 70.66275  ? 226 PRO B CD  1 
ATOM   5550 N  N   . ILE B 1 227 ? 42.63734  -10.49428 -82.51327 1.000 65.03108  ? 227 ILE B N   1 
ATOM   5551 C  CA  . ILE B 1 227 ? 41.91036  -9.64347  -81.57538 1.000 66.45535  ? 227 ILE B CA  1 
ATOM   5552 C  C   . ILE B 1 227 ? 42.69704  -9.44477  -80.28347 1.000 63.30327  ? 227 ILE B C   1 
ATOM   5553 O  O   . ILE B 1 227 ? 42.66393  -8.36101  -79.68955 1.000 61.32520  ? 227 ILE B O   1 
ATOM   5554 C  CB  . ILE B 1 227 ? 40.51261  -10.23434 -81.31264 1.000 57.96969  ? 227 ILE B CB  1 
ATOM   5555 C  CG1 . ILE B 1 227 ? 39.80981  -10.52846 -82.64282 1.000 62.22202  ? 227 ILE B CG1 1 
ATOM   5556 C  CG2 . ILE B 1 227 ? 39.67553  -9.27944  -80.48002 1.000 49.61864  ? 227 ILE B CG2 1 
ATOM   5557 C  CD1 . ILE B 1 227 ? 38.38916  -11.03112 -82.49256 1.000 60.11659  ? 227 ILE B CD1 1 
ATOM   5558 N  N   . ARG B 1 228 ? 43.41600  -10.47047 -79.82792 1.000 57.86264  ? 228 ARG B N   1 
ATOM   5559 C  CA  . ARG B 1 228 ? 44.20466  -10.33466 -78.60706 1.000 56.51398  ? 228 ARG B CA  1 
ATOM   5560 C  C   . ARG B 1 228 ? 45.40501  -9.42125  -78.82082 1.000 56.93357  ? 228 ARG B C   1 
ATOM   5561 O  O   . ARG B 1 228 ? 45.70495  -8.57069  -77.97376 1.000 59.80049  ? 228 ARG B O   1 
ATOM   5562 C  CB  . ARG B 1 228 ? 44.65691  -11.71110 -78.11996 1.000 59.56721  ? 228 ARG B CB  1 
ATOM   5563 C  CG  . ARG B 1 228 ? 45.71201  -11.66009 -77.03701 1.000 64.76789  ? 228 ARG B CG  1 
ATOM   5564 C  CD  . ARG B 1 228 ? 45.18603  -10.99469 -75.77921 1.000 65.74050  ? 228 ARG B CD  1 
ATOM   5565 N  NE  . ARG B 1 228 ? 44.24374  -11.84526 -75.06469 1.000 64.87356  ? 228 ARG B NE  1 
ATOM   5566 C  CZ  . ARG B 1 228 ? 44.56899  -12.62031 -74.03989 1.000 67.01203  ? 228 ARG B CZ  1 
ATOM   5567 N  NH1 . ARG B 1 228 ? 45.80723  -12.67081 -73.57823 1.000 58.53029  ? 228 ARG B NH1 1 
ATOM   5568 N  NH2 . ARG B 1 228 ? 43.62851  -13.36219 -73.46366 1.000 70.53968  ? 228 ARG B NH2 1 
ATOM   5569 N  N   . ARG B 1 229 ? 46.09986  -9.58110  -79.94898 1.000 59.38150  ? 229 ARG B N   1 
ATOM   5570 C  CA  . ARG B 1 229 ? 47.25298  -8.73891  -80.24860 1.000 57.56377  ? 229 ARG B CA  1 
ATOM   5571 C  C   . ARG B 1 229 ? 46.86728  -7.26718  -80.33362 1.000 59.75962  ? 229 ARG B C   1 
ATOM   5572 O  O   . ARG B 1 229 ? 47.67279  -6.39033  -79.99754 1.000 61.13802  ? 229 ARG B O   1 
ATOM   5573 C  CB  . ARG B 1 229 ? 47.89685  -9.21469  -81.54959 1.000 67.91348  ? 229 ARG B CB  1 
ATOM   5574 C  CG  . ARG B 1 229 ? 48.94549  -8.30033  -82.15116 1.000 70.51177  ? 229 ARG B CG  1 
ATOM   5575 C  CD  . ARG B 1 229 ? 48.93462  -8.45037  -83.66196 1.000 58.80573  ? 229 ARG B CD  1 
ATOM   5576 N  NE  . ARG B 1 229 ? 47.65176  -8.04624  -84.22635 1.000 68.04204  ? 229 ARG B NE  1 
ATOM   5577 C  CZ  . ARG B 1 229 ? 47.23036  -8.37346  -85.44018 1.000 85.25121  ? 229 ARG B CZ  1 
ATOM   5578 N  NH1 . ARG B 1 229 ? 47.95974  -9.13015  -86.24401 1.000 65.52999  ? 229 ARG B NH1 1 
ATOM   5579 N  NH2 . ARG B 1 229 ? 46.04410  -7.93752  -85.85478 1.000 75.71537  ? 229 ARG B NH2 1 
ATOM   5580 N  N   . ASP B 1 230 ? 45.64173  -6.97769  -80.76920 1.000 60.35447  ? 230 ASP B N   1 
ATOM   5581 C  CA  . ASP B 1 230 ? 45.17661  -5.59803  -80.84844 1.000 66.58595  ? 230 ASP B CA  1 
ATOM   5582 C  C   . ASP B 1 230 ? 44.63123  -5.09705  -79.51607 1.000 57.26074  ? 230 ASP B C   1 
ATOM   5583 O  O   . ASP B 1 230 ? 44.72520  -3.89984  -79.22476 1.000 66.63051  ? 230 ASP B O   1 
ATOM   5584 C  CB  . ASP B 1 230 ? 44.12052  -5.47768  -81.94690 1.000 68.68561  ? 230 ASP B CB  1 
ATOM   5585 C  CG  . ASP B 1 230 ? 44.67281  -5.82671  -83.31556 1.000 70.38631  ? 230 ASP B CG  1 
ATOM   5586 O  OD1 . ASP B 1 230 ? 45.91172  -5.88250  -83.45658 1.000 66.25070  ? 230 ASP B OD1 1 
ATOM   5587 O  OD2 . ASP B 1 230 ? 43.87676  -6.05316  -84.24821 1.000 66.85514  ? 230 ASP B OD2 1 
ATOM   5588 N  N   . TYR B 1 231 ? 44.04980  -5.98756  -78.70798 1.000 66.92270  ? 231 TYR B N   1 
ATOM   5589 C  CA  . TYR B 1 231 ? 43.62055  -5.60908  -77.36411 1.000 55.74850  ? 231 TYR B CA  1 
ATOM   5590 C  C   . TYR B 1 231 ? 44.81347  -5.21843  -76.49941 1.000 53.78445  ? 231 TYR B C   1 
ATOM   5591 O  O   . TYR B 1 231 ? 44.74505  -4.25150  -75.73186 1.000 52.84083  ? 231 TYR B O   1 
ATOM   5592 C  CB  . TYR B 1 231 ? 42.84144  -6.76173  -76.72786 1.000 51.04074  ? 231 TYR B CB  1 
ATOM   5593 C  CG  . TYR B 1 231 ? 42.18351  -6.45191  -75.39760 1.000 53.13574  ? 231 TYR B CG  1 
ATOM   5594 C  CD1 . TYR B 1 231 ? 42.87947  -6.59565  -74.20376 1.000 53.78975  ? 231 TYR B CD1 1 
ATOM   5595 C  CD2 . TYR B 1 231 ? 40.85594  -6.04595  -75.33528 1.000 56.58351  ? 231 TYR B CD2 1 
ATOM   5596 C  CE1 . TYR B 1 231 ? 42.27866  -6.32479  -72.98832 1.000 53.84242  ? 231 TYR B CE1 1 
ATOM   5597 C  CE2 . TYR B 1 231 ? 40.24657  -5.77435  -74.12282 1.000 57.70974  ? 231 TYR B CE2 1 
ATOM   5598 C  CZ  . TYR B 1 231 ? 40.96268  -5.91629  -72.95344 1.000 59.91249  ? 231 TYR B CZ  1 
ATOM   5599 O  OH  . TYR B 1 231 ? 40.36123  -5.64637  -71.74568 1.000 56.15425  ? 231 TYR B OH  1 
ATOM   5600 N  N   . TYR B 1 232 ? 45.91455  -5.96729  -76.60485 1.000 53.53478  ? 232 TYR B N   1 
ATOM   5601 C  CA  . TYR B 1 232 ? 47.12874  -5.61378  -75.87659 1.000 48.66740  ? 232 TYR B CA  1 
ATOM   5602 C  C   . TYR B 1 232 ? 47.67894  -4.27263  -76.34283 1.000 66.83844  ? 232 TYR B C   1 
ATOM   5603 O  O   . TYR B 1 232 ? 48.15993  -3.47330  -75.53087 1.000 69.83800  ? 232 TYR B O   1 
ATOM   5604 C  CB  . TYR B 1 232 ? 48.17845  -6.71028  -76.04508 1.000 47.04877  ? 232 TYR B CB  1 
ATOM   5605 C  CG  . TYR B 1 232 ? 49.48735  -6.41389  -75.35353 1.000 59.08036  ? 232 TYR B CG  1 
ATOM   5606 C  CD1 . TYR B 1 232 ? 49.62744  -6.60294  -73.98491 1.000 58.08302  ? 232 TYR B CD1 1 
ATOM   5607 C  CD2 . TYR B 1 232 ? 50.58553  -5.95273  -76.06886 1.000 52.39353  ? 232 TYR B CD2 1 
ATOM   5608 C  CE1 . TYR B 1 232 ? 50.82002  -6.33732  -73.34659 1.000 54.04454  ? 232 TYR B CE1 1 
ATOM   5609 C  CE2 . TYR B 1 232 ? 51.78451  -5.68447  -75.43870 1.000 59.45841  ? 232 TYR B CE2 1 
ATOM   5610 C  CZ  . TYR B 1 232 ? 51.89472  -5.87863  -74.07662 1.000 63.22115  ? 232 TYR B CZ  1 
ATOM   5611 O  OH  . TYR B 1 232 ? 53.08200  -5.61527  -73.43610 1.000 63.55935  ? 232 TYR B OH  1 
ATOM   5612 N  N   . ARG B 1 233 ? 47.63601  -4.01826  -77.65232 1.000 61.92948  ? 233 ARG B N   1 
ATOM   5613 C  CA  . ARG B 1 233 ? 48.01496  -2.70557  -78.16319 1.000 62.40852  ? 233 ARG B CA  1 
ATOM   5614 C  C   . ARG B 1 233 ? 47.12830  -1.61981  -77.57407 1.000 64.14474  ? 233 ARG B C   1 
ATOM   5615 O  O   . ARG B 1 233 ? 47.60159  -0.52550  -77.24588 1.000 72.21064  ? 233 ARG B O   1 
ATOM   5616 C  CB  . ARG B 1 233 ? 47.92696  -2.69431  -79.68798 1.000 65.07554  ? 233 ARG B CB  1 
ATOM   5617 C  CG  . ARG B 1 233 ? 48.20431  -1.34335  -80.31622 1.000 62.71701  ? 233 ARG B CG  1 
ATOM   5618 C  CD  . ARG B 1 233 ? 49.64372  -0.92741  -80.10226 1.000 66.26014  ? 233 ARG B CD  1 
ATOM   5619 N  NE  . ARG B 1 233 ? 49.93959  0.32984   -80.77494 1.000 76.44911  ? 233 ARG B NE  1 
ATOM   5620 C  CZ  . ARG B 1 233 ? 51.16234  0.77966   -81.01646 1.000 81.92387  ? 233 ARG B CZ  1 
ATOM   5621 N  NH1 . ARG B 1 233 ? 52.23491  0.08407   -80.67573 1.000 87.87523  ? 233 ARG B NH1 1 
ATOM   5622 N  NH2 . ARG B 1 233 ? 51.31227  1.95469   -81.61848 1.000 78.89381  ? 233 ARG B NH2 1 
ATOM   5623 N  N   . GLN B 1 234 ? 45.83226  -1.90511  -77.44368 1.000 62.73956  ? 234 GLN B N   1 
ATOM   5624 C  CA  . GLN B 1 234 ? 44.92688  -0.95847  -76.80728 1.000 60.08336  ? 234 GLN B CA  1 
ATOM   5625 C  C   . GLN B 1 234 ? 45.30983  -0.72625  -75.35078 1.000 71.04428  ? 234 GLN B C   1 
ATOM   5626 O  O   . GLN B 1 234 ? 45.14528  0.38187   -74.82942 1.000 76.88851  ? 234 GLN B O   1 
ATOM   5627 C  CB  . GLN B 1 234 ? 43.48847  -1.46130  -76.91571 1.000 57.90562  ? 234 GLN B CB  1 
ATOM   5628 C  CG  . GLN B 1 234 ? 42.43813  -0.39651  -76.66312 1.000 81.98613  ? 234 GLN B CG  1 
ATOM   5629 C  CD  . GLN B 1 234 ? 42.41338  0.67259   -77.73956 1.000 81.34292  ? 234 GLN B CD  1 
ATOM   5630 O  OE1 . GLN B 1 234 ? 42.83672  0.44228   -78.87264 1.000 68.05696  ? 234 GLN B OE1 1 
ATOM   5631 N  NE2 . GLN B 1 234 ? 41.90989  1.85045   -77.38937 1.000 66.01156  ? 234 GLN B NE2 1 
ATOM   5632 N  N   . ILE B 1 235 ? 45.82068  -1.76061  -74.67536 1.000 61.87830  ? 235 ILE B N   1 
ATOM   5633 C  CA  . ILE B 1 235 ? 46.25563  -1.59980  -73.28944 1.000 59.34265  ? 235 ILE B CA  1 
ATOM   5634 C  C   . ILE B 1 235 ? 47.37878  -0.57577  -73.20004 1.000 64.15784  ? 235 ILE B C   1 
ATOM   5635 O  O   . ILE B 1 235 ? 47.32153  0.36881   -72.40320 1.000 78.79684  ? 235 ILE B O   1 
ATOM   5636 C  CB  . ILE B 1 235 ? 46.69428  -2.95228  -72.69979 1.000 67.87056  ? 235 ILE B CB  1 
ATOM   5637 C  CG1 . ILE B 1 235 ? 45.49064  -3.84958  -72.42018 1.000 63.39592  ? 235 ILE B CG1 1 
ATOM   5638 C  CG2 . ILE B 1 235 ? 47.51574  -2.74253  -71.43479 1.000 61.05615  ? 235 ILE B CG2 1 
ATOM   5639 C  CD1 . ILE B 1 235 ? 45.88457  -5.21522  -71.90281 1.000 58.54938  ? 235 ILE B CD1 1 
ATOM   5640 N  N   . LEU B 1 236 ? 48.41890  -0.74788  -74.01972 1.000 65.83432  ? 236 LEU B N   1 
ATOM   5641 C  CA  . LEU B 1 236 ? 49.57972  0.13381   -73.93355 1.000 72.38196  ? 236 LEU B CA  1 
ATOM   5642 C  C   . LEU B 1 236 ? 49.22399  1.55812   -74.33807 1.000 64.57954  ? 236 LEU B C   1 
ATOM   5643 O  O   . LEU B 1 236 ? 49.72195  2.52220   -73.74664 1.000 63.00973  ? 236 LEU B O   1 
ATOM   5644 C  CB  . LEU B 1 236 ? 50.71786  -0.40953  -74.79650 1.000 62.02221  ? 236 LEU B CB  1 
ATOM   5645 C  CG  . LEU B 1 236 ? 51.19887  -1.81924  -74.43830 1.000 68.02076  ? 236 LEU B CG  1 
ATOM   5646 C  CD1 . LEU B 1 236 ? 52.40994  -2.21430  -75.27263 1.000 72.26213  ? 236 LEU B CD1 1 
ATOM   5647 C  CD2 . LEU B 1 236 ? 51.50236  -1.94195  -72.94882 1.000 65.22248  ? 236 LEU B CD2 1 
ATOM   5648 N  N   . GLU B 1 237 ? 48.37279  1.70952   -75.35317 1.000 70.29003  ? 237 GLU B N   1 
ATOM   5649 C  CA  . GLU B 1 237 ? 47.92867  3.03853   -75.75609 1.000 68.64325  ? 237 GLU B CA  1 
ATOM   5650 C  C   . GLU B 1 237 ? 47.08610  3.69355   -74.66708 1.000 72.94796  ? 237 GLU B C   1 
ATOM   5651 O  O   . GLU B 1 237 ? 47.20924  4.89823   -74.41866 1.000 79.24794  ? 237 GLU B O   1 
ATOM   5652 C  CB  . GLU B 1 237 ? 47.15144  2.95170   -77.07008 1.000 69.41369  ? 237 GLU B CB  1 
ATOM   5653 C  CG  . GLU B 1 237 ? 46.44331  4.23543   -77.46744 1.000 96.36420  ? 237 GLU B CG  1 
ATOM   5654 C  CD  . GLU B 1 237 ? 47.40480  5.34539   -77.84397 1.000 111.53869 ? 237 GLU B CD  1 
ATOM   5655 O  OE1 . GLU B 1 237 ? 48.15812  5.17813   -78.82689 1.000 110.50927 ? 237 GLU B OE1 1 
ATOM   5656 O  OE2 . GLU B 1 237 ? 47.40730  6.38515   -77.15233 1.000 95.25067  ? 237 GLU B OE2 1 
ATOM   5657 N  N   . GLU B 1 238 ? 46.22839  2.91568   -74.00248 1.000 70.36297  ? 238 GLU B N   1 
ATOM   5658 C  CA  . GLU B 1 238 ? 45.34387  3.49089   -72.99423 1.000 66.19252  ? 238 GLU B CA  1 
ATOM   5659 C  C   . GLU B 1 238 ? 46.10345  3.84680   -71.72214 1.000 72.30727  ? 238 GLU B C   1 
ATOM   5660 O  O   . GLU B 1 238 ? 45.82753  4.87877   -71.09780 1.000 83.98212  ? 238 GLU B O   1 
ATOM   5661 C  CB  . GLU B 1 238 ? 44.19288  2.53393   -72.68647 1.000 64.53672  ? 238 GLU B CB  1 
ATOM   5662 C  CG  . GLU B 1 238 ? 43.11145  2.50372   -73.75420 1.000 71.77111  ? 238 GLU B CG  1 
ATOM   5663 C  CD  . GLU B 1 238 ? 41.97689  1.55880   -73.40850 1.000 87.03208  ? 238 GLU B CD  1 
ATOM   5664 O  OE1 . GLU B 1 238 ? 41.98913  0.99660   -72.29250 1.000 83.30637  ? 238 GLU B OE1 1 
ATOM   5665 O  OE2 . GLU B 1 238 ? 41.07205  1.37657   -74.25088 1.000 89.51205  ? 238 GLU B OE2 1 
ATOM   5666 N  N   . PHE B 1 239 ? 47.05917  3.00892   -71.31551 1.000 63.65978  ? 239 PHE B N   1 
ATOM   5667 C  CA  . PHE B 1 239 ? 47.82183  3.31437   -70.11069 1.000 62.09884  ? 239 PHE B CA  1 
ATOM   5668 C  C   . PHE B 1 239 ? 48.79951  4.45809   -70.33801 1.000 70.04324  ? 239 PHE B C   1 
ATOM   5669 O  O   . PHE B 1 239 ? 49.10538  5.20335   -69.40076 1.000 74.72428  ? 239 PHE B O   1 
ATOM   5670 C  CB  . PHE B 1 239 ? 48.55301  2.06952   -69.61315 1.000 69.52344  ? 239 PHE B CB  1 
ATOM   5671 C  CG  . PHE B 1 239 ? 47.77919  1.29309   -68.59247 1.000 78.30270  ? 239 PHE B CG  1 
ATOM   5672 C  CD1 . PHE B 1 239 ? 47.84142  1.63754   -67.25196 1.000 62.51296  ? 239 PHE B CD1 1 
ATOM   5673 C  CD2 . PHE B 1 239 ? 46.97287  0.23379   -68.97290 1.000 70.40315  ? 239 PHE B CD2 1 
ATOM   5674 C  CE1 . PHE B 1 239 ? 47.12278  0.93422   -66.30960 1.000 52.55534  ? 239 PHE B CE1 1 
ATOM   5675 C  CE2 . PHE B 1 239 ? 46.25169  -0.47422  -68.03453 1.000 72.31428  ? 239 PHE B CE2 1 
ATOM   5676 C  CZ  . PHE B 1 239 ? 46.32393  -0.11945  -66.70229 1.000 76.58344  ? 239 PHE B CZ  1 
ATOM   5677 N  N   . ARG B 1 240 ? 49.29740  4.61718   -71.56487 1.000 71.29732  ? 240 ARG B N   1 
ATOM   5678 C  CA  . ARG B 1 240 ? 50.12743  5.77777   -71.86531 1.000 72.06630  ? 240 ARG B CA  1 
ATOM   5679 C  C   . ARG B 1 240 ? 49.28786  7.04673   -71.94042 1.000 79.72998  ? 240 ARG B C   1 
ATOM   5680 O  O   . ARG B 1 240 ? 49.73927  8.12121   -71.52680 1.000 74.40244  ? 240 ARG B O   1 
ATOM   5681 C  CB  . ARG B 1 240 ? 50.88897  5.55877   -73.17121 1.000 63.68472  ? 240 ARG B CB  1 
ATOM   5682 C  CG  . ARG B 1 240 ? 51.93290  6.62379   -73.44549 1.000 67.67757  ? 240 ARG B CG  1 
ATOM   5683 C  CD  . ARG B 1 240 ? 52.49802  6.50369   -74.84542 1.000 71.22053  ? 240 ARG B CD  1 
ATOM   5684 N  NE  . ARG B 1 240 ? 52.67844  7.81688   -75.45108 1.000 73.71748  ? 240 ARG B NE  1 
ATOM   5685 C  CZ  . ARG B 1 240 ? 51.72423  8.47835   -76.09107 1.000 76.96658  ? 240 ARG B CZ  1 
ATOM   5686 N  NH1 . ARG B 1 240 ? 50.51223  7.96867   -76.24160 1.000 76.87301  ? 240 ARG B NH1 1 
ATOM   5687 N  NH2 . ARG B 1 240 ? 51.99208  9.68052   -76.59221 1.000 57.30375  ? 240 ARG B NH2 1 
ATOM   5688 N  N   . SER B 1 241 ? 48.06299  6.94169   -72.46265 1.000 75.54347  ? 241 SER B N   1 
ATOM   5689 C  CA  . SER B 1 241 ? 47.16411  8.08667   -72.53169 1.000 66.06650  ? 241 SER B CA  1 
ATOM   5690 C  C   . SER B 1 241 ? 46.64408  8.50874   -71.16530 1.000 71.99943  ? 241 SER B C   1 
ATOM   5691 O  O   . SER B 1 241 ? 46.02034  9.57041   -71.06056 1.000 86.63685  ? 241 SER B O   1 
ATOM   5692 C  CB  . SER B 1 241 ? 45.98924  7.78104   -73.46359 1.000 70.38151  ? 241 SER B CB  1 
ATOM   5693 O  OG  . SER B 1 241 ? 46.43496  7.61844   -74.79926 1.000 76.36158  ? 241 SER B OG  1 
ATOM   5694 N  N   . ASP B 1 242 ? 46.87036  7.70614   -70.12642 1.000 67.36852  ? 242 ASP B N   1 
ATOM   5695 C  CA  . ASP B 1 242 ? 46.61904  8.11250   -68.75198 1.000 68.00237  ? 242 ASP B CA  1 
ATOM   5696 C  C   . ASP B 1 242 ? 47.91478  8.45577   -68.02434 1.000 67.32310  ? 242 ASP B C   1 
ATOM   5697 O  O   . ASP B 1 242 ? 47.96559  8.40559   -66.79049 1.000 68.54468  ? 242 ASP B O   1 
ATOM   5698 C  CB  . ASP B 1 242 ? 45.84950  7.01945   -68.00726 1.000 74.83900  ? 242 ASP B CB  1 
ATOM   5699 C  CG  . ASP B 1 242 ? 45.13283  7.54505   -66.77752 1.000 77.57204  ? 242 ASP B CG  1 
ATOM   5700 O  OD1 . ASP B 1 242 ? 44.37827  8.53350   -66.90429 1.000 71.47710  ? 242 ASP B OD1 1 
ATOM   5701 O  OD2 . ASP B 1 242 ? 45.32354  6.96695   -65.68523 1.000 75.08079  ? 242 ASP B OD2 1 
ATOM   5702 N  N   . ASN B 1 243 ? 48.96536  8.78709   -68.77788 1.000 65.60557  ? 243 ASN B N   1 
ATOM   5703 C  CA  . ASN B 1 243 ? 50.24574  9.23394   -68.22782 1.000 64.29778  ? 243 ASN B CA  1 
ATOM   5704 C  C   . ASN B 1 243 ? 50.86169  8.19585   -67.29184 1.000 67.83956  ? 243 ASN B C   1 
ATOM   5705 O  O   . ASN B 1 243 ? 51.46591  8.53225   -66.27322 1.000 74.33182  ? 243 ASN B O   1 
ATOM   5706 C  CB  . ASN B 1 243 ? 50.10019  10.58575  -67.52840 1.000 63.42205  ? 243 ASN B CB  1 
ATOM   5707 C  CG  . ASN B 1 243 ? 49.67680  11.68484  -68.48040 1.000 65.84706  ? 243 ASN B CG  1 
ATOM   5708 O  OD1 . ASN B 1 243 ? 50.50555  12.27707  -69.17160 1.000 79.64171  ? 243 ASN B OD1 1 
ATOM   5709 N  ND2 . ASN B 1 243 ? 48.38063  11.96052  -68.52556 1.000 69.57403  ? 243 ASN B ND2 1 
ATOM   5710 N  N   . VAL B 1 244 ? 50.71501  6.92208   -67.64255 1.000 68.05580  ? 244 VAL B N   1 
ATOM   5711 C  CA  . VAL B 1 244 ? 51.42566  5.83175   -66.98568 1.000 66.44537  ? 244 VAL B CA  1 
ATOM   5712 C  C   . VAL B 1 244 ? 52.48161  5.32770   -67.95677 1.000 68.38059  ? 244 VAL B C   1 
ATOM   5713 O  O   . VAL B 1 244 ? 52.16724  4.98828   -69.10415 1.000 64.60650  ? 244 VAL B O   1 
ATOM   5714 C  CB  . VAL B 1 244 ? 50.47308  4.70166   -66.56089 1.000 63.01166  ? 244 VAL B CB  1 
ATOM   5715 C  CG1 . VAL B 1 244 ? 51.19729  3.69942   -65.67306 1.000 73.24886  ? 244 VAL B CG1 1 
ATOM   5716 C  CG2 . VAL B 1 244 ? 49.25393  5.27489   -65.85597 1.000 60.09449  ? 244 VAL B CG2 1 
ATOM   5717 N  N   . GLN B 1 245 ? 53.73073  5.27949   -67.50008 1.000 67.58966  ? 245 GLN B N   1 
ATOM   5718 C  CA  . GLN B 1 245 ? 54.86211  5.07593   -68.39251 1.000 68.00556  ? 245 GLN B CA  1 
ATOM   5719 C  C   . GLN B 1 245 ? 55.41389  3.65624   -68.37735 1.000 74.30935  ? 245 GLN B C   1 
ATOM   5720 O  O   . GLN B 1 245 ? 56.26129  3.33332   -69.21575 1.000 76.24012  ? 245 GLN B O   1 
ATOM   5721 C  CB  . GLN B 1 245 ? 55.98568  6.05722   -68.03609 1.000 74.79339  ? 245 GLN B CB  1 
ATOM   5722 C  CG  . GLN B 1 245 ? 55.52619  7.50193   -67.92070 1.000 72.71721  ? 245 GLN B CG  1 
ATOM   5723 C  CD  . GLN B 1 245 ? 56.59265  8.48365   -68.35709 1.000 78.35296  ? 245 GLN B CD  1 
ATOM   5724 O  OE1 . GLN B 1 245 ? 56.35365  9.33422   -69.21352 1.000 101.32559 ? 245 GLN B OE1 1 
ATOM   5725 N  NE2 . GLN B 1 245 ? 57.77953  8.36811   -67.77413 1.000 73.04485  ? 245 GLN B NE2 1 
ATOM   5726 N  N   . TYR B 1 246 ? 54.95786  2.80332   -67.46477 1.000 68.98670  ? 246 TYR B N   1 
ATOM   5727 C  CA  . TYR B 1 246 ? 55.50905  1.46323   -67.33147 1.000 65.10491  ? 246 TYR B CA  1 
ATOM   5728 C  C   . TYR B 1 246 ? 54.41390  0.54149   -66.81755 1.000 67.20178  ? 246 TYR B C   1 
ATOM   5729 O  O   . TYR B 1 246 ? 53.59534  0.94780   -65.99115 1.000 68.23791  ? 246 TYR B O   1 
ATOM   5730 C  CB  . TYR B 1 246 ? 56.72080  1.47475   -66.39028 1.000 61.47881  ? 246 TYR B CB  1 
ATOM   5731 C  CG  . TYR B 1 246 ? 57.39762  0.14073   -66.18368 1.000 64.76858  ? 246 TYR B CG  1 
ATOM   5732 C  CD1 . TYR B 1 246 ? 58.20653  -0.41088  -67.16790 1.000 72.79111  ? 246 TYR B CD1 1 
ATOM   5733 C  CD2 . TYR B 1 246 ? 57.25359  -0.55156  -64.99026 1.000 69.51625  ? 246 TYR B CD2 1 
ATOM   5734 C  CE1 . TYR B 1 246 ? 58.83592  -1.62555  -66.97681 1.000 73.13517  ? 246 TYR B CE1 1 
ATOM   5735 C  CE2 . TYR B 1 246 ? 57.88098  -1.76314  -64.78859 1.000 71.38609  ? 246 TYR B CE2 1 
ATOM   5736 C  CZ  . TYR B 1 246 ? 58.66974  -2.29735  -65.78578 1.000 67.40072  ? 246 TYR B CZ  1 
ATOM   5737 O  OH  . TYR B 1 246 ? 59.29681  -3.50590  -65.59254 1.000 57.24991  ? 246 TYR B OH  1 
ATOM   5738 N  N   . VAL B 1 247 ? 54.37893  -0.68508  -67.33070 1.000 64.19145  ? 247 VAL B N   1 
ATOM   5739 C  CA  . VAL B 1 247 ? 53.37368  -1.66203  -66.92734 1.000 68.97937  ? 247 VAL B CA  1 
ATOM   5740 C  C   . VAL B 1 247 ? 54.03446  -3.02518  -66.78106 1.000 74.33759  ? 247 VAL B C   1 
ATOM   5741 O  O   . VAL B 1 247 ? 54.90084  -3.39892  -67.57872 1.000 76.66613  ? 247 VAL B O   1 
ATOM   5742 C  CB  . VAL B 1 247 ? 52.19525  -1.72638  -67.92579 1.000 64.03346  ? 247 VAL B CB  1 
ATOM   5743 C  CG1 . VAL B 1 247 ? 51.35092  -0.46308  -67.84571 1.000 52.30945  ? 247 VAL B CG1 1 
ATOM   5744 C  CG2 . VAL B 1 247 ? 52.69748  -1.93614  -69.34527 1.000 54.26927  ? 247 VAL B CG2 1 
ATOM   5745 N  N   . GLU B 1 248 ? 53.63147  -3.76098  -65.74807 1.000 65.08968  ? 248 GLU B N   1 
ATOM   5746 C  CA  . GLU B 1 248 ? 54.02224  -5.15589  -65.55470 1.000 68.98682  ? 248 GLU B CA  1 
ATOM   5747 C  C   . GLU B 1 248 ? 52.73361  -5.97126  -65.49960 1.000 78.00305  ? 248 GLU B C   1 
ATOM   5748 O  O   . GLU B 1 248 ? 52.06873  -6.03233  -64.46010 1.000 73.51375  ? 248 GLU B O   1 
ATOM   5749 C  CB  . GLU B 1 248 ? 54.86807  -5.33122  -64.29672 1.000 63.43817  ? 248 GLU B CB  1 
ATOM   5750 C  CG  . GLU B 1 248 ? 56.26433  -4.73771  -64.41736 1.000 63.61915  ? 248 GLU B CG  1 
ATOM   5751 C  CD  . GLU B 1 248 ? 57.14609  -5.04943  -63.22314 1.000 64.92882  ? 248 GLU B CD  1 
ATOM   5752 O  OE1 . GLU B 1 248 ? 56.75498  -5.90217  -62.40112 1.000 65.51467  ? 248 GLU B OE1 1 
ATOM   5753 O  OE2 . GLU B 1 248 ? 58.23226  -4.44278  -63.10720 1.000 53.44669  ? 248 GLU B OE2 1 
ATOM   5754 N  N   . VAL B 1 249 ? 52.38882  -6.59396  -66.62389 1.000 68.19555  ? 249 VAL B N   1 
ATOM   5755 C  CA  . VAL B 1 249 ? 51.09944  -7.24525  -66.81872 1.000 65.01863  ? 249 VAL B CA  1 
ATOM   5756 C  C   . VAL B 1 249 ? 51.23393  -8.73568  -66.54253 1.000 74.85041  ? 249 VAL B C   1 
ATOM   5757 O  O   . VAL B 1 249 ? 52.23559  -9.36367  -66.90736 1.000 77.32587  ? 249 VAL B O   1 
ATOM   5758 C  CB  . VAL B 1 249 ? 50.57155  -6.98937  -68.24418 1.000 54.31777  ? 249 VAL B CB  1 
ATOM   5759 C  CG1 . VAL B 1 249 ? 49.20690  -7.62947  -68.44471 1.000 60.37239  ? 249 VAL B CG1 1 
ATOM   5760 C  CG2 . VAL B 1 249 ? 50.50528  -5.49559  -68.51960 1.000 72.99432  ? 249 VAL B CG2 1 
ATOM   5761 N  N   . ARG B 1 250 ? 50.22247  -9.30115  -65.88969 1.000 72.19893  ? 250 ARG B N   1 
ATOM   5762 C  CA  . ARG B 1 250 ? 50.11545  -10.73741 -65.67643 1.000 74.25870  ? 250 ARG B CA  1 
ATOM   5763 C  C   . ARG B 1 250 ? 49.18888  -11.32505 -66.73286 1.000 64.50585  ? 250 ARG B C   1 
ATOM   5764 O  O   . ARG B 1 250 ? 48.11687  -10.77196 -67.00027 1.000 71.68103  ? 250 ARG B O   1 
ATOM   5765 C  CB  . ARG B 1 250 ? 49.58627  -11.04597 -64.27508 1.000 66.32406  ? 250 ARG B CB  1 
ATOM   5766 C  CG  . ARG B 1 250 ? 50.54282  -10.68921 -63.15433 1.000 56.77880  ? 250 ARG B CG  1 
ATOM   5767 C  CD  . ARG B 1 250 ? 49.82094  -10.67960 -61.82027 1.000 63.99011  ? 250 ARG B CD  1 
ATOM   5768 N  NE  . ARG B 1 250 ? 50.74224  -10.53973 -60.70015 1.000 61.68172  ? 250 ARG B NE  1 
ATOM   5769 C  CZ  . ARG B 1 250 ? 51.26943  -9.39079  -60.30148 1.000 74.64807  ? 250 ARG B CZ  1 
ATOM   5770 N  NH1 . ARG B 1 250 ? 51.01135  -8.25616  -60.93130 1.000 83.54945  ? 250 ARG B NH1 1 
ATOM   5771 N  NH2 . ARG B 1 250 ? 52.07830  -9.37991  -59.24586 1.000 78.56409  ? 250 ARG B NH2 1 
ATOM   5772 N  N   . SER B 1 251 ? 49.60172  -12.43849 -67.33187 1.000 68.38110  ? 251 SER B N   1 
ATOM   5773 C  CA  . SER B 1 251 ? 48.84965  -13.03422 -68.42570 1.000 72.64784  ? 251 SER B CA  1 
ATOM   5774 C  C   . SER B 1 251 ? 48.95761  -14.55058 -68.36592 1.000 80.47777  ? 251 SER B C   1 
ATOM   5775 O  O   . SER B 1 251 ? 49.95011  -15.10134 -67.88094 1.000 72.64460  ? 251 SER B O   1 
ATOM   5776 C  CB  . SER B 1 251 ? 49.34981  -12.53095 -69.78704 1.000 72.75219  ? 251 SER B CB  1 
ATOM   5777 O  OG  . SER B 1 251 ? 48.76503  -13.25917 -70.85188 1.000 72.95076  ? 251 SER B OG  1 
ATOM   5778 N  N   . SER B 1 252 ? 47.91546  -15.21985 -68.86733 1.000 74.51748  ? 252 SER B N   1 
ATOM   5779 C  CA  . SER B 1 252 ? 47.98453  -16.66374 -69.06266 1.000 71.20554  ? 252 SER B CA  1 
ATOM   5780 C  C   . SER B 1 252 ? 48.94698  -17.02387 -70.18885 1.000 73.93003  ? 252 SER B C   1 
ATOM   5781 O  O   . SER B 1 252 ? 49.55931  -18.09846 -70.15795 1.000 79.17971  ? 252 SER B O   1 
ATOM   5782 C  CB  . SER B 1 252 ? 46.58871  -17.22065 -69.34108 1.000 67.54059  ? 252 SER B CB  1 
ATOM   5783 O  OG  . SER B 1 252 ? 45.90316  -16.42525 -70.29176 1.000 78.59768  ? 252 SER B OG  1 
ATOM   5784 N  N   . LEU B 1 253 ? 49.06135  -16.15558 -71.19906 1.000 73.53293  ? 253 LEU B N   1 
ATOM   5785 C  CA  . LEU B 1 253 ? 50.07797  -16.22463 -72.24831 1.000 76.82757  ? 253 LEU B CA  1 
ATOM   5786 C  C   . LEU B 1 253 ? 49.89728  -17.38179 -73.22491 1.000 80.70869  ? 253 LEU B C   1 
ATOM   5787 O  O   . LEU B 1 253 ? 50.64457  -17.48057 -74.20352 1.000 94.60682  ? 253 LEU B O   1 
ATOM   5788 C  CB  . LEU B 1 253 ? 51.48076  -16.30335 -71.64111 1.000 67.19282  ? 253 LEU B CB  1 
ATOM   5789 C  CG  . LEU B 1 253 ? 52.17605  -15.00096 -71.24703 1.000 75.25448  ? 253 LEU B CG  1 
ATOM   5790 C  CD1 . LEU B 1 253 ? 53.59410  -15.28437 -70.77867 1.000 75.12962  ? 253 LEU B CD1 1 
ATOM   5791 C  CD2 . LEU B 1 253 ? 52.18240  -14.03171 -72.41507 1.000 71.12927  ? 253 LEU B CD2 1 
ATOM   5792 N  N   . SER B 1 254 ? 48.92188  -18.25550 -72.99141 1.000 71.62654  ? 254 SER B N   1 
ATOM   5793 C  CA  . SER B 1 254 ? 48.74289  -19.43532 -73.82450 1.000 68.90719  ? 254 SER B CA  1 
ATOM   5794 C  C   . SER B 1 254 ? 47.27803  -19.59853 -74.19885 1.000 78.49550  ? 254 SER B C   1 
ATOM   5795 O  O   . SER B 1 254 ? 46.37946  -19.18173 -73.46274 1.000 80.90783  ? 254 SER B O   1 
ATOM   5796 C  CB  . SER B 1 254 ? 49.24070  -20.70556 -73.11878 1.000 69.26652  ? 254 SER B CB  1 
ATOM   5797 O  OG  . SER B 1 254 ? 48.41654  -21.03675 -72.01491 1.000 86.57014  ? 254 SER B OG  1 
ATOM   5798 N  N   . GLY B 1 255 ? 47.04835  -20.21845 -75.35498 1.000 62.97345  ? 255 GLY B N   1 
ATOM   5799 C  CA  . GLY B 1 255 ? 45.70994  -20.51486 -75.82201 1.000 62.17625  ? 255 GLY B CA  1 
ATOM   5800 C  C   . GLY B 1 255 ? 45.19631  -19.62647 -76.93300 1.000 67.59878  ? 255 GLY B C   1 
ATOM   5801 O  O   . GLY B 1 255 ? 44.03174  -19.77491 -77.32407 1.000 71.87782  ? 255 GLY B O   1 
ATOM   5802 N  N   . PHE B 1 256 ? 46.00945  -18.70718 -77.45082 1.000 73.43893  ? 256 PHE B N   1 
ATOM   5803 C  CA  . PHE B 1 256 ? 45.57607  -17.87871 -78.56830 1.000 76.51018  ? 256 PHE B CA  1 
ATOM   5804 C  C   . PHE B 1 256 ? 45.28068  -18.75711 -79.77673 1.000 79.83173  ? 256 PHE B C   1 
ATOM   5805 O  O   . PHE B 1 256 ? 46.13092  -19.53647 -80.21611 1.000 67.81426  ? 256 PHE B O   1 
ATOM   5806 C  CB  . PHE B 1 256 ? 46.64788  -16.84335 -78.91134 1.000 69.08142  ? 256 PHE B CB  1 
ATOM   5807 C  CG  . PHE B 1 256 ? 47.05678  -15.98449 -77.74876 1.000 67.33744  ? 256 PHE B CG  1 
ATOM   5808 C  CD1 . PHE B 1 256 ? 46.13494  -15.60853 -76.78613 1.000 70.51231  ? 256 PHE B CD1 1 
ATOM   5809 C  CD2 . PHE B 1 256 ? 48.36840  -15.56018 -77.61439 1.000 66.94757  ? 256 PHE B CD2 1 
ATOM   5810 C  CE1 . PHE B 1 256 ? 46.51398  -14.82452 -75.71553 1.000 64.33826  ? 256 PHE B CE1 1 
ATOM   5811 C  CE2 . PHE B 1 256 ? 48.75172  -14.77411 -76.54584 1.000 61.94901  ? 256 PHE B CE2 1 
ATOM   5812 C  CZ  . PHE B 1 256 ? 47.82393  -14.40536 -75.59560 1.000 62.56602  ? 256 PHE B CZ  1 
ATOM   5813 N  N   . PHE B 1 257 ? 44.07107  -18.63246 -80.31226 1.000 77.20086  ? 257 PHE B N   1 
ATOM   5814 C  CA  . PHE B 1 257 ? 43.61112  -19.48877 -81.39335 1.000 70.33710  ? 257 PHE B CA  1 
ATOM   5815 C  C   . PHE B 1 257 ? 43.38450  -18.67625 -82.66042 1.000 75.38065  ? 257 PHE B C   1 
ATOM   5816 O  O   . PHE B 1 257 ? 43.05728  -17.48721 -82.60939 1.000 71.87864  ? 257 PHE B O   1 
ATOM   5817 C  CB  . PHE B 1 257 ? 42.32228  -20.22749 -81.00949 1.000 62.76618  ? 257 PHE B CB  1 
ATOM   5818 C  CG  . PHE B 1 257 ? 41.10645  -19.34292 -80.93385 1.000 66.72746  ? 257 PHE B CG  1 
ATOM   5819 C  CD1 . PHE B 1 257 ? 40.84584  -18.59962 -79.79587 1.000 75.17797  ? 257 PHE B CD1 1 
ATOM   5820 C  CD2 . PHE B 1 257 ? 40.21278  -19.27263 -81.99219 1.000 73.31368  ? 257 PHE B CD2 1 
ATOM   5821 C  CE1 . PHE B 1 257 ? 39.72916  -17.79133 -79.71892 1.000 78.42025  ? 257 PHE B CE1 1 
ATOM   5822 C  CE2 . PHE B 1 257 ? 39.09348  -18.46457 -81.92021 1.000 79.95681  ? 257 PHE B CE2 1 
ATOM   5823 C  CZ  . PHE B 1 257 ? 38.85250  -17.72352 -80.78194 1.000 81.80668  ? 257 PHE B CZ  1 
ATOM   5824 N  N   . GLU B 1 258 ? 43.56346  -19.33716 -83.79825 1.000 70.31007  ? 258 GLU B N   1 
ATOM   5825 C  CA  . GLU B 1 258 ? 43.37040  -18.73174 -85.10542 1.000 64.67284  ? 258 GLU B CA  1 
ATOM   5826 C  C   . GLU B 1 258 ? 42.00753  -19.12268 -85.66632 1.000 68.53788  ? 258 GLU B C   1 
ATOM   5827 O  O   . GLU B 1 258 ? 41.26898  -19.91915 -85.08232 1.000 71.97165  ? 258 GLU B O   1 
ATOM   5828 C  CB  . GLU B 1 258 ? 44.48563  -19.15876 -86.06757 1.000 60.37478  ? 258 GLU B CB  1 
ATOM   5829 C  CG  . GLU B 1 258 ? 45.89798  -18.86370 -85.57689 1.000 70.25077  ? 258 GLU B CG  1 
ATOM   5830 C  CD  . GLU B 1 258 ? 46.25273  -17.38672 -85.61167 1.000 78.92828  ? 258 GLU B CD  1 
ATOM   5831 O  OE1 . GLU B 1 258 ? 45.46056  -16.58394 -86.15141 1.000 81.81582  ? 258 GLU B OE1 1 
ATOM   5832 O  OE2 . GLU B 1 258 ? 47.33570  -17.03187 -85.09974 1.000 81.22751  ? 258 GLU B OE2 1 
ATOM   5833 N  N   . LEU B 1 259 ? 41.67923  -18.54343 -86.82359 1.000 65.71173  ? 259 LEU B N   1 
ATOM   5834 C  CA  . LEU B 1 259 ? 40.40843  -18.85625 -87.46870 1.000 57.77627  ? 259 LEU B CA  1 
ATOM   5835 C  C   . LEU B 1 259 ? 40.33492  -20.31836 -87.88660 1.000 70.09413  ? 259 LEU B C   1 
ATOM   5836 O  O   . LEU B 1 259 ? 39.25038  -20.91347 -87.86934 1.000 72.77110  ? 259 LEU B O   1 
ATOM   5837 C  CB  . LEU B 1 259 ? 40.19310  -17.94706 -88.67859 1.000 57.81995  ? 259 LEU B CB  1 
ATOM   5838 C  CG  . LEU B 1 259 ? 39.73412  -16.51887 -88.38118 1.000 53.26400  ? 259 LEU B CG  1 
ATOM   5839 C  CD1 . LEU B 1 259 ? 39.80229  -15.65972 -89.63295 1.000 63.60834  ? 259 LEU B CD1 1 
ATOM   5840 C  CD2 . LEU B 1 259 ? 38.32382  -16.52600 -87.81452 1.000 55.11231  ? 259 LEU B CD2 1 
ATOM   5841 N  N   . ASP B 1 260 ? 41.46700  -20.91455 -88.27111 1.000 71.11960  ? 260 ASP B N   1 
ATOM   5842 C  CA  . ASP B 1 260 ? 41.47145  -22.32390 -88.64048 1.000 57.65842  ? 260 ASP B CA  1 
ATOM   5843 C  C   . ASP B 1 260 ? 41.37179  -23.24990 -87.43610 1.000 69.31695  ? 260 ASP B C   1 
ATOM   5844 O  O   . ASP B 1 260 ? 40.96432  -24.40556 -87.59595 1.000 79.75230  ? 260 ASP B O   1 
ATOM   5845 C  CB  . ASP B 1 260 ? 42.72887  -22.66103 -89.45222 1.000 62.05926  ? 260 ASP B CB  1 
ATOM   5846 C  CG  . ASP B 1 260 ? 43.99714  -22.67553 -88.61152 1.000 66.23715  ? 260 ASP B CG  1 
ATOM   5847 O  OD1 . ASP B 1 260 ? 44.07356  -21.93911 -87.60588 1.000 79.27630  ? 260 ASP B OD1 1 
ATOM   5848 O  OD2 . ASP B 1 260 ? 44.92922  -23.42734 -88.96588 1.000 58.28873  ? 260 ASP B OD2 1 
ATOM   5849 N  N   . GLY B 1 261 ? 41.72526  -22.77751 -86.24347 1.000 70.99170  ? 261 GLY B N   1 
ATOM   5850 C  CA  . GLY B 1 261 ? 41.65718  -23.58390 -85.03584 1.000 68.78240  ? 261 GLY B CA  1 
ATOM   5851 C  C   . GLY B 1 261 ? 42.97784  -23.79344 -84.32412 1.000 70.27554  ? 261 GLY B C   1 
ATOM   5852 O  O   . GLY B 1 261 ? 42.97289  -24.29150 -83.18963 1.000 67.71610  ? 261 GLY B O   1 
ATOM   5853 N  N   . THR B 1 262 ? 44.10734  -23.44018 -84.93717 1.000 71.42324  ? 262 THR B N   1 
ATOM   5854 C  CA  . THR B 1 262 ? 45.41626  -23.64743 -84.32537 1.000 64.26017  ? 262 THR B CA  1 
ATOM   5855 C  C   . THR B 1 262 ? 45.50781  -22.96600 -82.96648 1.000 71.04635  ? 262 THR B C   1 
ATOM   5856 O  O   . THR B 1 262 ? 45.33954  -21.74875 -82.85763 1.000 84.99207  ? 262 THR B O   1 
ATOM   5857 C  CB  . THR B 1 262 ? 46.51194  -23.11565 -85.25431 1.000 62.99172  ? 262 THR B CB  1 
ATOM   5858 O  OG1 . THR B 1 262 ? 46.40479  -23.74968 -86.53431 1.000 65.25726  ? 262 THR B OG1 1 
ATOM   5859 C  CG2 . THR B 1 262 ? 47.89424  -23.39202 -84.66945 1.000 66.63624  ? 262 THR B CG2 1 
ATOM   5860 N  N   . VAL B 1 263 ? 45.78605  -23.75579 -81.93353 1.000 67.89029  ? 263 VAL B N   1 
ATOM   5861 C  CA  . VAL B 1 263 ? 45.99407  -23.24806 -80.58233 1.000 72.72855  ? 263 VAL B CA  1 
ATOM   5862 C  C   . VAL B 1 263 ? 47.49131  -23.21284 -80.31187 1.000 76.57475  ? 263 VAL B C   1 
ATOM   5863 O  O   . VAL B 1 263 ? 48.19921  -24.19564 -80.56866 1.000 83.39532  ? 263 VAL B O   1 
ATOM   5864 C  CB  . VAL B 1 263 ? 45.25928  -24.11298 -79.54435 1.000 60.29668  ? 263 VAL B CB  1 
ATOM   5865 C  CG1 . VAL B 1 263 ? 45.61603  -23.67394 -78.13189 1.000 62.66999  ? 263 VAL B CG1 1 
ATOM   5866 C  CG2 . VAL B 1 263 ? 43.75435  -24.04354 -79.76612 1.000 52.78762  ? 263 VAL B CG2 1 
ATOM   5867 N  N   . HIS B 1 264 ? 47.97476  -22.08611 -79.79422 1.000 77.04235  ? 264 HIS B N   1 
ATOM   5868 C  CA  . HIS B 1 264 ? 49.40160  -21.84930 -79.64207 1.000 80.70738  ? 264 HIS B CA  1 
ATOM   5869 C  C   . HIS B 1 264 ? 49.86611  -22.14193 -78.21963 1.000 85.33414  ? 264 HIS B C   1 
ATOM   5870 O  O   . HIS B 1 264 ? 49.07854  -22.45008 -77.32227 1.000 78.98653  ? 264 HIS B O   1 
ATOM   5871 C  CB  . HIS B 1 264 ? 49.74654  -20.40420 -80.01653 1.000 81.26766  ? 264 HIS B CB  1 
ATOM   5872 C  CG  . HIS B 1 264 ? 49.50299  -20.07790 -81.45568 1.000 82.77071  ? 264 HIS B CG  1 
ATOM   5873 N  ND1 . HIS B 1 264 ? 50.33144  -20.51311 -82.46746 1.000 72.78863  ? 264 HIS B ND1 1 
ATOM   5874 C  CD2 . HIS B 1 264 ? 48.52705  -19.35524 -82.05300 1.000 80.76587  ? 264 HIS B CD2 1 
ATOM   5875 C  CE1 . HIS B 1 264 ? 49.87472  -20.07492 -83.62685 1.000 77.59151  ? 264 HIS B CE1 1 
ATOM   5876 N  NE2 . HIS B 1 264 ? 48.78061  -19.36975 -83.40294 1.000 73.27204  ? 264 HIS B NE2 1 
ATOM   5877 N  N   . ASP B 1 265 ? 51.17783  -22.04449 -78.03143 1.000 80.64117  ? 265 ASP B N   1 
ATOM   5878 C  CA  . ASP B 1 265 ? 51.82931  -22.25076 -76.75031 1.000 76.22380  ? 265 ASP B CA  1 
ATOM   5879 C  C   . ASP B 1 265 ? 52.07505  -20.90296 -76.07071 1.000 80.60717  ? 265 ASP B C   1 
ATOM   5880 O  O   . ASP B 1 265 ? 51.55978  -19.86293 -76.49359 1.000 74.93963  ? 265 ASP B O   1 
ATOM   5881 C  CB  . ASP B 1 265 ? 53.12708  -23.04189 -76.94735 1.000 70.44064  ? 265 ASP B CB  1 
ATOM   5882 C  CG  . ASP B 1 265 ? 54.22616  -22.21601 -77.58829 1.000 77.44859  ? 265 ASP B CG  1 
ATOM   5883 O  OD1 . ASP B 1 265 ? 53.91077  -21.29803 -78.37553 1.000 99.28726  ? 265 ASP B OD1 1 
ATOM   5884 O  OD2 . ASP B 1 265 ? 55.41262  -22.48676 -77.30482 1.000 81.21563  ? 265 ASP B OD2 1 
ATOM   5885 N  N   . ALA B 1 266 ? 52.85923  -20.92065 -74.99115 1.000 79.17821  ? 266 ALA B N   1 
ATOM   5886 C  CA  . ALA B 1 266 ? 53.14791  -19.69337 -74.25696 1.000 74.85493  ? 266 ALA B CA  1 
ATOM   5887 C  C   . ALA B 1 266 ? 54.17823  -18.81904 -74.96615 1.000 79.99159  ? 266 ALA B C   1 
ATOM   5888 O  O   . ALA B 1 266 ? 54.01705  -17.59510 -75.01848 1.000 84.86454  ? 266 ALA B O   1 
ATOM   5889 C  CB  . ALA B 1 266 ? 53.63016  -20.03164 -72.84573 1.000 69.73475  ? 266 ALA B CB  1 
ATOM   5890 N  N   . GLU B 1 267 ? 55.24358  -19.41857 -75.50890 1.000 78.68011  ? 267 GLU B N   1 
ATOM   5891 C  CA  . GLU B 1 267 ? 56.30607  -18.61882 -76.11306 1.000 71.66762  ? 267 GLU B CA  1 
ATOM   5892 C  C   . GLU B 1 267 ? 55.80606  -17.83226 -77.31717 1.000 78.47453  ? 267 GLU B C   1 
ATOM   5893 O  O   . GLU B 1 267 ? 56.34939  -16.76702 -77.62933 1.000 77.09681  ? 267 GLU B O   1 
ATOM   5894 C  CB  . GLU B 1 267 ? 57.48509  -19.51185 -76.50436 1.000 75.56769  ? 267 GLU B CB  1 
ATOM   5895 C  CG  . GLU B 1 267 ? 58.75200  -18.74574 -76.87544 1.000 75.86751  ? 267 GLU B CG  1 
ATOM   5896 C  CD  . GLU B 1 267 ? 59.98154  -19.63356 -76.92611 1.000 81.55910  ? 267 GLU B CD  1 
ATOM   5897 O  OE1 . GLU B 1 267 ? 59.84260  -20.85721 -76.71790 1.000 93.49253  ? 267 GLU B OE1 1 
ATOM   5898 O  OE2 . GLU B 1 267 ? 61.08704  -19.10651 -77.17159 1.000 72.91646  ? 267 GLU B OE2 1 
ATOM   5899 N  N   . PHE B 1 268 ? 54.78565  -18.33893 -78.01042 1.000 75.65381  ? 268 PHE B N   1 
ATOM   5900 C  CA  . PHE B 1 268 ? 54.15099  -17.55049 -79.06087 1.000 74.10802  ? 268 PHE B CA  1 
ATOM   5901 C  C   . PHE B 1 268 ? 53.52534  -16.28596 -78.48632 1.000 78.11112  ? 268 PHE B C   1 
ATOM   5902 O  O   . PHE B 1 268 ? 53.66528  -15.19547 -79.05112 1.000 78.02530  ? 268 PHE B O   1 
ATOM   5903 C  CB  . PHE B 1 268 ? 53.09899  -18.38798 -79.78813 1.000 68.51375  ? 268 PHE B CB  1 
ATOM   5904 C  CG  . PHE B 1 268 ? 52.37599  -17.63839 -80.87052 1.000 78.41955  ? 268 PHE B CG  1 
ATOM   5905 C  CD1 . PHE B 1 268 ? 52.97334  -17.42903 -82.10289 1.000 67.36205  ? 268 PHE B CD1 1 
ATOM   5906 C  CD2 . PHE B 1 268 ? 51.10074  -17.14163 -80.65731 1.000 77.47505  ? 268 PHE B CD2 1 
ATOM   5907 C  CE1 . PHE B 1 268 ? 52.31206  -16.73703 -83.10229 1.000 52.66250  ? 268 PHE B CE1 1 
ATOM   5908 C  CE2 . PHE B 1 268 ? 50.43512  -16.44965 -81.65287 1.000 73.18725  ? 268 PHE B CE2 1 
ATOM   5909 C  CZ  . PHE B 1 268 ? 51.04165  -16.24795 -82.87612 1.000 56.80640  ? 268 PHE B CZ  1 
ATOM   5910 N  N   . GLY B 1 269 ? 52.82127  -16.41822 -77.36170 1.000 85.62722  ? 269 GLY B N   1 
ATOM   5911 C  CA  . GLY B 1 269 ? 52.21603  -15.25349 -76.73610 1.000 80.53639  ? 269 GLY B CA  1 
ATOM   5912 C  C   . GLY B 1 269 ? 53.24231  -14.25843 -76.23117 1.000 68.60521  ? 269 GLY B C   1 
ATOM   5913 O  O   . GLY B 1 269 ? 53.08269  -13.04576 -76.39289 1.000 69.98980  ? 269 GLY B O   1 
ATOM   5914 N  N   . LEU B 1 270 ? 54.30730  -14.75923 -75.60042 1.000 68.26247  ? 270 LEU B N   1 
ATOM   5915 C  CA  . LEU B 1 270 ? 55.34967  -13.87215 -75.09425 1.000 60.91776  ? 270 LEU B CA  1 
ATOM   5916 C  C   . LEU B 1 270 ? 56.00866  -13.09522 -76.22560 1.000 71.91136  ? 270 LEU B C   1 
ATOM   5917 O  O   . LEU B 1 270 ? 56.31447  -11.90777 -76.07497 1.000 83.03821  ? 270 LEU B O   1 
ATOM   5918 C  CB  . LEU B 1 270 ? 56.39271  -14.66907 -74.31301 1.000 56.10142  ? 270 LEU B CB  1 
ATOM   5919 C  CG  . LEU B 1 270 ? 57.39985  -13.82632 -73.52954 1.000 49.41925  ? 270 LEU B CG  1 
ATOM   5920 C  CD1 . LEU B 1 270 ? 56.72017  -13.10641 -72.37315 1.000 63.29582  ? 270 LEU B CD1 1 
ATOM   5921 C  CD2 . LEU B 1 270 ? 58.54867  -14.68173 -73.02897 1.000 63.81786  ? 270 LEU B CD2 1 
ATOM   5922 N  N   . ASN B 1 271 ? 56.24457  -13.74903 -77.36466 1.000 67.76317  ? 271 ASN B N   1 
ATOM   5923 C  CA  . ASN B 1 271 ? 56.80950  -13.03792 -78.50653 1.000 64.32480  ? 271 ASN B CA  1 
ATOM   5924 C  C   . ASN B 1 271 ? 55.77554  -12.14739 -79.18272 1.000 73.49273  ? 271 ASN B C   1 
ATOM   5925 O  O   . ASN B 1 271 ? 56.14007  -11.13960 -79.80001 1.000 80.58390  ? 271 ASN B O   1 
ATOM   5926 C  CB  . ASN B 1 271 ? 57.40512  -14.02167 -79.51553 1.000 66.26187  ? 271 ASN B CB  1 
ATOM   5927 C  CG  . ASN B 1 271 ? 58.76098  -14.54251 -79.08846 1.000 70.27956  ? 271 ASN B CG  1 
ATOM   5928 O  OD1 . ASN B 1 271 ? 59.73158  -13.78868 -79.01237 1.000 67.22490  ? 271 ASN B OD1 1 
ATOM   5929 N  ND2 . ASN B 1 271 ? 58.83858  -15.83995 -78.81943 1.000 76.39510  ? 271 ASN B ND2 1 
ATOM   5930 N  N   . LEU B 1 272 ? 54.49161  -12.50174 -79.09275 1.000 64.74289  ? 272 LEU B N   1 
ATOM   5931 C  CA  . LEU B 1 272 ? 53.45074  -11.61573 -79.60214 1.000 72.91599  ? 272 LEU B CA  1 
ATOM   5932 C  C   . LEU B 1 272 ? 53.40613  -10.32104 -78.80051 1.000 69.14123  ? 272 LEU B C   1 
ATOM   5933 O  O   . LEU B 1 272 ? 53.33594  -9.22607  -79.37002 1.000 63.54045  ? 272 LEU B O   1 
ATOM   5934 C  CB  . LEU B 1 272 ? 52.09334  -12.31803 -79.56812 1.000 63.83398  ? 272 LEU B CB  1 
ATOM   5935 C  CG  . LEU B 1 272 ? 50.93677  -11.50751 -80.16575 1.000 69.04362  ? 272 LEU B CG  1 
ATOM   5936 C  CD1 . LEU B 1 272 ? 50.91458  -11.62068 -81.68445 1.000 56.86493  ? 272 LEU B CD1 1 
ATOM   5937 C  CD2 . LEU B 1 272 ? 49.60011  -11.91868 -79.56594 1.000 65.65374  ? 272 LEU B CD2 1 
ATOM   5938 N  N   . TYR B 1 273 ? 53.45719  -10.43039 -77.47112 1.000 66.18535  ? 273 TYR B N   1 
ATOM   5939 C  CA  . TYR B 1 273 ? 53.51158  -9.24216  -76.62729 1.000 67.19378  ? 273 TYR B CA  1 
ATOM   5940 C  C   . TYR B 1 273 ? 54.82300  -8.49005  -76.81591 1.000 75.88606  ? 273 TYR B C   1 
ATOM   5941 O  O   . TYR B 1 273 ? 54.84089  -7.25381  -76.81510 1.000 81.48302  ? 273 TYR B O   1 
ATOM   5942 C  CB  . TYR B 1 273 ? 53.32517  -9.62803  -75.15885 1.000 59.36369  ? 273 TYR B CB  1 
ATOM   5943 C  CG  . TYR B 1 273 ? 51.89446  -9.91374  -74.75585 1.000 55.94382  ? 273 TYR B CG  1 
ATOM   5944 C  CD1 . TYR B 1 273 ? 50.84371  -9.69039  -75.63540 1.000 55.99358  ? 273 TYR B CD1 1 
ATOM   5945 C  CD2 . TYR B 1 273 ? 51.59401  -10.39084 -73.48575 1.000 64.81683  ? 273 TYR B CD2 1 
ATOM   5946 C  CE1 . TYR B 1 273 ? 49.53445  -9.94528  -75.26652 1.000 59.99196  ? 273 TYR B CE1 1 
ATOM   5947 C  CE2 . TYR B 1 273 ? 50.28787  -10.64786 -73.10715 1.000 72.21660  ? 273 TYR B CE2 1 
ATOM   5948 C  CZ  . TYR B 1 273 ? 49.26214  -10.42293 -74.00146 1.000 59.95944  ? 273 TYR B CZ  1 
ATOM   5949 O  OH  . TYR B 1 273 ? 47.96053  -10.67627 -73.63158 1.000 53.90077  ? 273 TYR B OH  1 
ATOM   5950 N  N   . LYS B 1 274 ? 55.93101  -9.21804  -76.97581 1.000 71.65469  ? 274 LYS B N   1 
ATOM   5951 C  CA  . LYS B 1 274 ? 57.23450  -8.57062  -77.08760 1.000 73.33060  ? 274 LYS B CA  1 
ATOM   5952 C  C   . LYS B 1 274 ? 57.34815  -7.75585  -78.37148 1.000 81.34995  ? 274 LYS B C   1 
ATOM   5953 O  O   . LYS B 1 274 ? 57.94192  -6.67159  -78.37144 1.000 80.24371  ? 274 LYS B O   1 
ATOM   5954 C  CB  . LYS B 1 274 ? 58.34672  -9.61750  -77.01031 1.000 61.26851  ? 274 LYS B CB  1 
ATOM   5955 C  CG  . LYS B 1 274 ? 59.74855  -9.04020  -77.08887 1.000 69.89570  ? 274 LYS B CG  1 
ATOM   5956 C  CD  . LYS B 1 274 ? 60.80150  -10.11496 -76.88462 1.000 75.36705  ? 274 LYS B CD  1 
ATOM   5957 C  CE  . LYS B 1 274 ? 62.19139  -9.57941  -77.18095 1.000 77.96731  ? 274 LYS B CE  1 
ATOM   5958 N  NZ  . LYS B 1 274 ? 62.31623  -9.15243  -78.60282 1.000 96.00216  ? 274 LYS B NZ  1 
ATOM   5959 N  N   . SER B 1 275 ? 56.79287  -8.25960  -79.47605 1.000 77.73210  ? 275 SER B N   1 
ATOM   5960 C  CA  . SER B 1 275 ? 56.84877  -7.51709  -80.73218 1.000 82.04124  ? 275 SER B CA  1 
ATOM   5961 C  C   . SER B 1 275 ? 56.02438  -6.23675  -80.65287 1.000 85.89508  ? 275 SER B C   1 
ATOM   5962 O  O   . SER B 1 275 ? 56.48064  -5.16596  -81.06989 1.000 86.14376  ? 275 SER B O   1 
ATOM   5963 C  CB  . SER B 1 275 ? 56.37181  -8.39700  -81.88857 1.000 80.44687  ? 275 SER B CB  1 
ATOM   5964 O  OG  . SER B 1 275 ? 54.99417  -8.70766  -81.77130 1.000 93.86373  ? 275 SER B OG  1 
ATOM   5965 N  N   . VAL B 1 276 ? 54.80339  -6.32916  -80.11958 1.000 73.46380  ? 276 VAL B N   1 
ATOM   5966 C  CA  . VAL B 1 276 ? 53.94811  -5.15035  -80.00238 1.000 73.68627  ? 276 VAL B CA  1 
ATOM   5967 C  C   . VAL B 1 276 ? 54.57748  -4.12585  -79.06728 1.000 82.23435  ? 276 VAL B C   1 
ATOM   5968 O  O   . VAL B 1 276 ? 54.54738  -2.91786  -79.33441 1.000 88.92403  ? 276 VAL B O   1 
ATOM   5969 C  CB  . VAL B 1 276 ? 52.53784  -5.55545  -79.53357 1.000 54.75091  ? 276 VAL B CB  1 
ATOM   5970 C  CG1 . VAL B 1 276 ? 51.63717  -4.33275  -79.42459 1.000 67.20706  ? 276 VAL B CG1 1 
ATOM   5971 C  CG2 . VAL B 1 276 ? 51.93659  -6.57381  -80.48493 1.000 52.19512  ? 276 VAL B CG2 1 
ATOM   5972 N  N   . THR B 1 277 ? 55.15395  -4.59115  -77.95542 1.000 77.76262  ? 277 THR B N   1 
ATOM   5973 C  CA  . THR B 1 277 ? 55.78192  -3.68226  -77.00048 1.000 73.26766  ? 277 THR B CA  1 
ATOM   5974 C  C   . THR B 1 277 ? 56.93907  -2.92038  -77.63323 1.000 82.90974  ? 277 THR B C   1 
ATOM   5975 O  O   . THR B 1 277 ? 57.08027  -1.71000  -77.42819 1.000 89.48357  ? 277 THR B O   1 
ATOM   5976 C  CB  . THR B 1 277 ? 56.26709  -4.46068  -75.77719 1.000 73.78990  ? 277 THR B CB  1 
ATOM   5977 O  OG1 . THR B 1 277 ? 55.14447  -5.04151  -75.10481 1.000 79.23683  ? 277 THR B OG1 1 
ATOM   5978 C  CG2 . THR B 1 277 ? 57.01011  -3.54394  -74.81628 1.000 68.34337  ? 277 THR B CG2 1 
ATOM   5979 N  N   . GLU B 1 278 ? 57.77592  -3.60914  -78.41085 1.000 83.00886  ? 278 GLU B N   1 
ATOM   5980 C  CA  . GLU B 1 278 ? 58.94707  -2.95412  -78.98268 1.000 87.37074  ? 278 GLU B CA  1 
ATOM   5981 C  C   . GLU B 1 278 ? 58.57148  -2.01185  -80.11993 1.000 83.78902  ? 278 GLU B C   1 
ATOM   5982 O  O   . GLU B 1 278 ? 59.26252  -1.01127  -80.34434 1.000 84.25451  ? 278 GLU B O   1 
ATOM   5983 C  CB  . GLU B 1 278 ? 59.95758  -4.00329  -79.43981 1.000 90.18676  ? 278 GLU B CB  1 
ATOM   5984 C  CG  . GLU B 1 278 ? 60.59669  -4.74209  -78.27174 1.000 89.39703  ? 278 GLU B CG  1 
ATOM   5985 C  CD  . GLU B 1 278 ? 61.49680  -5.87870  -78.70399 1.000 101.80793 ? 278 GLU B CD  1 
ATOM   5986 O  OE1 . GLU B 1 278 ? 61.42273  -6.28673  -79.88214 1.000 110.82168 ? 278 GLU B OE1 1 
ATOM   5987 O  OE2 . GLU B 1 278 ? 62.28080  -6.36238  -77.86047 1.000 105.07360 ? 278 GLU B OE2 1 
ATOM   5988 N  N   . GLU B 1 279 ? 57.49442  -2.30953  -80.84985 1.000 81.05575  ? 279 GLU B N   1 
ATOM   5989 C  CA  . GLU B 1 279 ? 56.95749  -1.32763  -81.78606 1.000 79.08122  ? 279 GLU B CA  1 
ATOM   5990 C  C   . GLU B 1 279 ? 56.41755  -0.11333  -81.04259 1.000 83.79707  ? 279 GLU B C   1 
ATOM   5991 O  O   . GLU B 1 279 ? 56.51544  1.01975   -81.52895 1.000 88.31335  ? 279 GLU B O   1 
ATOM   5992 C  CB  . GLU B 1 279 ? 55.86482  -1.96018  -82.64853 1.000 89.23343  ? 279 GLU B CB  1 
ATOM   5993 C  CG  . GLU B 1 279 ? 56.34829  -3.09434  -83.53855 1.000 106.68289 ? 279 GLU B CG  1 
ATOM   5994 C  CD  . GLU B 1 279 ? 55.24241  -3.67456  -84.40066 1.000 115.17636 ? 279 GLU B CD  1 
ATOM   5995 O  OE1 . GLU B 1 279 ? 54.13666  -3.09412  -84.42286 1.000 111.79728 ? 279 GLU B OE1 1 
ATOM   5996 O  OE2 . GLU B 1 279 ? 55.47981  -4.71230  -85.05520 1.000 107.34850 ? 279 GLU B OE2 1 
ATOM   5997 N  N   . PHE B 1 280 ? 55.84141  -0.33610  -79.85887 1.000 88.15142  ? 280 PHE B N   1 
ATOM   5998 C  CA  . PHE B 1 280 ? 55.32456  0.76123   -79.04787 1.000 70.18386  ? 280 PHE B CA  1 
ATOM   5999 C  C   . PHE B 1 280 ? 56.45502  1.63929   -78.52491 1.000 74.44861  ? 280 PHE B C   1 
ATOM   6000 O  O   . PHE B 1 280 ? 56.39676  2.87100   -78.62890 1.000 83.84820  ? 280 PHE B O   1 
ATOM   6001 C  CB  . PHE B 1 280 ? 54.49548  0.20147   -77.89124 1.000 68.54734  ? 280 PHE B CB  1 
ATOM   6002 C  CG  . PHE B 1 280 ? 53.56083  1.20171   -77.27074 1.000 76.06617  ? 280 PHE B CG  1 
ATOM   6003 C  CD1 . PHE B 1 280 ? 52.29246  1.39397   -77.79139 1.000 71.21502  ? 280 PHE B CD1 1 
ATOM   6004 C  CD2 . PHE B 1 280 ? 53.94403  1.94144   -76.16302 1.000 76.65800  ? 280 PHE B CD2 1 
ATOM   6005 C  CE1 . PHE B 1 280 ? 51.42551  2.30806   -77.22684 1.000 70.52253  ? 280 PHE B CE1 1 
ATOM   6006 C  CE2 . PHE B 1 280 ? 53.08047  2.85917   -75.59348 1.000 71.58338  ? 280 PHE B CE2 1 
ATOM   6007 C  CZ  . PHE B 1 280 ? 51.81981  3.04207   -76.12707 1.000 69.93336  ? 280 PHE B CZ  1 
ATOM   6008 N  N   . GLN B 1 281 ? 57.49385  1.02006   -77.95424 1.000 70.31530  ? 281 GLN B N   1 
ATOM   6009 C  CA  . GLN B 1 281 ? 58.61119  1.78554   -77.40940 1.000 81.87818  ? 281 GLN B CA  1 
ATOM   6010 C  C   . GLN B 1 281 ? 59.28483  2.64018   -78.47519 1.000 87.55797  ? 281 GLN B C   1 
ATOM   6011 O  O   . GLN B 1 281 ? 59.78455  3.72928   -78.17106 1.000 83.70783  ? 281 GLN B O   1 
ATOM   6012 C  CB  . GLN B 1 281 ? 59.63424  0.84454   -76.76579 1.000 68.01189  ? 281 GLN B CB  1 
ATOM   6013 C  CG  . GLN B 1 281 ? 59.13342  0.10468   -75.53410 1.000 81.87176  ? 281 GLN B CG  1 
ATOM   6014 C  CD  . GLN B 1 281 ? 60.18066  -0.82815  -74.94883 1.000 89.39042  ? 281 GLN B CD  1 
ATOM   6015 O  OE1 . GLN B 1 281 ? 60.28696  -1.98934  -75.34517 1.000 92.52745  ? 281 GLN B OE1 1 
ATOM   6016 N  NE2 . GLN B 1 281 ? 60.96121  -0.32152  -74.00130 1.000 78.23463  ? 281 GLN B NE2 1 
ATOM   6017 N  N   . ARG B 1 282 ? 59.31430  2.16674   -79.72286 1.000 79.75647  ? 282 ARG B N   1 
ATOM   6018 C  CA  . ARG B 1 282 ? 59.93877  2.93794   -80.79203 1.000 69.91668  ? 282 ARG B CA  1 
ATOM   6019 C  C   . ARG B 1 282 ? 59.05113  4.08557   -81.26203 1.000 79.80762  ? 282 ARG B C   1 
ATOM   6020 O  O   . ARG B 1 282 ? 59.55591  5.16989   -81.57584 1.000 87.29848  ? 282 ARG B O   1 
ATOM   6021 C  CB  . ARG B 1 282 ? 60.29933  2.02238   -81.96286 1.000 78.20692  ? 282 ARG B CB  1 
ATOM   6022 C  CG  . ARG B 1 282 ? 61.49552  1.12548   -81.68643 1.000 98.14486  ? 282 ARG B CG  1 
ATOM   6023 C  CD  . ARG B 1 282 ? 61.99111  0.42833   -82.94518 1.000 94.51600  ? 282 ARG B CD  1 
ATOM   6024 N  NE  . ARG B 1 282 ? 61.22873  -0.77336  -83.25983 1.000 94.02620  ? 282 ARG B NE  1 
ATOM   6025 C  CZ  . ARG B 1 282 ? 60.24759  -0.82954  -84.15051 1.000 93.69910  ? 282 ARG B CZ  1 
ATOM   6026 N  NH1 . ARG B 1 282 ? 59.87415  0.23832   -84.83626 1.000 83.47049  ? 282 ARG B NH1 1 
ATOM   6027 N  NH2 . ARG B 1 282 ? 59.62768  -1.98785  -84.36075 1.000 92.34109  ? 282 ARG B NH2 1 
ATOM   6028 N  N   . GLU B 1 283 ? 57.73271  3.87215   -81.31804 1.000 76.49007  ? 283 GLU B N   1 
ATOM   6029 C  CA  . GLU B 1 283 ? 56.83898  4.93444   -81.77190 1.000 79.32132  ? 283 GLU B CA  1 
ATOM   6030 C  C   . GLU B 1 283 ? 56.76719  6.07279   -80.76343 1.000 89.02750  ? 283 GLU B C   1 
ATOM   6031 O  O   . GLU B 1 283 ? 56.79386  7.24869   -81.14442 1.000 88.14977  ? 283 GLU B O   1 
ATOM   6032 C  CB  . GLU B 1 283 ? 55.43935  4.38295   -82.03909 1.000 83.56541  ? 283 GLU B CB  1 
ATOM   6033 C  CG  . GLU B 1 283 ? 54.42311  5.47297   -82.36011 1.000 87.41233  ? 283 GLU B CG  1 
ATOM   6034 C  CD  . GLU B 1 283 ? 53.08767  4.92233   -82.80827 1.000 104.30759 ? 283 GLU B CD  1 
ATOM   6035 O  OE1 . GLU B 1 283 ? 52.98652  3.69213   -82.98665 1.000 108.38629 ? 283 GLU B OE1 1 
ATOM   6036 O  OE2 . GLU B 1 283 ? 52.14108  5.72012   -82.98229 1.000 108.22749 ? 283 GLU B OE2 1 
ATOM   6037 N  N   . TYR B 1 284 ? 56.67812  5.74773   -79.47412 1.000 92.77268  ? 284 TYR B N   1 
ATOM   6038 C  CA  . TYR B 1 284 ? 56.58104  6.74447   -78.40982 1.000 82.15214  ? 284 TYR B CA  1 
ATOM   6039 C  C   . TYR B 1 284 ? 57.82194  6.61389   -77.53808 1.000 90.28982  ? 284 TYR B C   1 
ATOM   6040 O  O   . TYR B 1 284 ? 57.83517  5.83656   -76.57005 1.000 84.99485  ? 284 TYR B O   1 
ATOM   6041 C  CB  . TYR B 1 284 ? 55.30523  6.56029   -77.59099 1.000 72.36159  ? 284 TYR B CB  1 
ATOM   6042 C  CG  . TYR B 1 284 ? 54.03816  6.53156   -78.41662 1.000 72.26745  ? 284 TYR B CG  1 
ATOM   6043 C  CD1 . TYR B 1 284 ? 53.45367  7.70585   -78.87105 1.000 78.03178  ? 284 TYR B CD1 1 
ATOM   6044 C  CD2 . TYR B 1 284 ? 53.42251  5.32870   -78.73442 1.000 76.29261  ? 284 TYR B CD2 1 
ATOM   6045 C  CE1 . TYR B 1 284 ? 52.29385  7.68247   -79.62303 1.000 80.95406  ? 284 TYR B CE1 1 
ATOM   6046 C  CE2 . TYR B 1 284 ? 52.26284  5.29539   -79.48542 1.000 79.01400  ? 284 TYR B CE2 1 
ATOM   6047 C  CZ  . TYR B 1 284 ? 51.70325  6.47479   -79.92696 1.000 76.90045  ? 284 TYR B CZ  1 
ATOM   6048 O  OH  . TYR B 1 284 ? 50.54893  6.44787   -80.67498 1.000 74.23680  ? 284 TYR B OH  1 
ATOM   6049 N  N   . PRO B 1 285 ? 58.89154  7.35527   -77.84559 1.000 94.16319  ? 285 PRO B N   1 
ATOM   6050 C  CA  . PRO B 1 285 ? 60.12860  7.23900   -77.05483 1.000 85.17176  ? 285 PRO B CA  1 
ATOM   6051 C  C   . PRO B 1 285 ? 59.99793  7.75029   -75.62989 1.000 78.32164  ? 285 PRO B C   1 
ATOM   6052 O  O   . PRO B 1 285 ? 60.92036  7.54337   -74.83092 1.000 90.30531  ? 285 PRO B O   1 
ATOM   6053 C  CB  . PRO B 1 285 ? 61.13850  8.07633   -77.85288 1.000 81.06013  ? 285 PRO B CB  1 
ATOM   6054 C  CG  . PRO B 1 285 ? 60.54448  8.20430   -79.22653 1.000 86.41922  ? 285 PRO B CG  1 
ATOM   6055 C  CD  . PRO B 1 285 ? 59.06441  8.22007   -79.02274 1.000 86.14483  ? 285 PRO B CD  1 
ATOM   6056 N  N   . ASP B 1 286 ? 58.89548  8.41750   -75.29041 1.000 83.88593  ? 286 ASP B N   1 
ATOM   6057 C  CA  . ASP B 1 286 ? 58.64361  8.83836   -73.91854 1.000 91.95776  ? 286 ASP B CA  1 
ATOM   6058 C  C   . ASP B 1 286 ? 58.22512  7.68054   -73.01971 1.000 88.35642  ? 286 ASP B C   1 
ATOM   6059 O  O   . ASP B 1 286 ? 58.26604  7.81852   -71.79249 1.000 85.97572  ? 286 ASP B O   1 
ATOM   6060 C  CB  . ASP B 1 286 ? 57.57623  9.93829   -73.89366 1.000 97.59993  ? 286 ASP B CB  1 
ATOM   6061 C  CG  . ASP B 1 286 ? 56.31518  9.56413   -74.67052 1.000 102.63373 ? 286 ASP B CG  1 
ATOM   6062 O  OD1 . ASP B 1 286 ? 56.40684  9.26173   -75.88050 1.000 87.93756  ? 286 ASP B OD1 1 
ATOM   6063 O  OD2 . ASP B 1 286 ? 55.22244  9.58356   -74.06499 1.000 101.91753 ? 286 ASP B OD2 1 
ATOM   6064 N  N   . PHE B 1 287 ? 57.83166  6.55097   -73.60064 1.000 78.01657  ? 287 PHE B N   1 
ATOM   6065 C  CA  . PHE B 1 287 ? 57.42338  5.38120   -72.83686 1.000 81.21424  ? 287 PHE B CA  1 
ATOM   6066 C  C   . PHE B 1 287 ? 58.64302  4.62559   -72.31600 1.000 76.15521  ? 287 PHE B C   1 
ATOM   6067 O  O   . PHE B 1 287 ? 59.71134  4.62622   -72.93406 1.000 71.83716  ? 287 PHE B O   1 
ATOM   6068 C  CB  . PHE B 1 287 ? 56.56110  4.46730   -73.71015 1.000 85.86179  ? 287 PHE B CB  1 
ATOM   6069 C  CG  . PHE B 1 287 ? 55.74341  3.47492   -72.93873 1.000 76.77216  ? 287 PHE B CG  1 
ATOM   6070 C  CD1 . PHE B 1 287 ? 54.65847  3.88926   -72.18467 1.000 72.96077  ? 287 PHE B CD1 1 
ATOM   6071 C  CD2 . PHE B 1 287 ? 56.04335  2.12447   -72.98818 1.000 73.64286  ? 287 PHE B CD2 1 
ATOM   6072 C  CE1 . PHE B 1 287 ? 53.89848  2.97712   -71.47972 1.000 68.29453  ? 287 PHE B CE1 1 
ATOM   6073 C  CE2 . PHE B 1 287 ? 55.28576  1.20703   -72.28728 1.000 80.38163  ? 287 PHE B CE2 1 
ATOM   6074 C  CZ  . PHE B 1 287 ? 54.21220  1.63407   -71.53177 1.000 76.74500  ? 287 PHE B CZ  1 
ATOM   6075 N  N   . ILE B 1 288 ? 58.47860  3.98054   -71.16350 1.000 84.31783  ? 288 ILE B N   1 
ATOM   6076 C  CA  . ILE B 1 288 ? 59.57621  3.22931   -70.55537 1.000 86.82301  ? 288 ILE B CA  1 
ATOM   6077 C  C   . ILE B 1 288 ? 59.59974  1.78503   -71.04040 1.000 81.27768  ? 288 ILE B C   1 
ATOM   6078 O  O   . ILE B 1 288 ? 60.63874  1.28690   -71.48144 1.000 87.56229  ? 288 ILE B O   1 
ATOM   6079 C  CB  . ILE B 1 288 ? 59.49412  3.30847   -69.01536 1.000 85.76651  ? 288 ILE B CB  1 
ATOM   6080 C  CG1 . ILE B 1 288 ? 59.65592  4.75730   -68.55038 1.000 75.58679  ? 288 ILE B CG1 1 
ATOM   6081 C  CG2 . ILE B 1 288 ? 60.55718  2.42405   -68.37500 1.000 71.17912  ? 288 ILE B CG2 1 
ATOM   6082 C  CD1 . ILE B 1 288 ? 59.73940  4.91626   -67.04760 1.000 69.17241  ? 288 ILE B CD1 1 
ATOM   6083 N  N   . GLY B 1 289 ? 58.47556  1.08896   -70.96789 1.000 83.23851  ? 289 GLY B N   1 
ATOM   6084 C  CA  . GLY B 1 289 ? 58.38931  -0.25862  -71.48963 1.000 85.15139  ? 289 GLY B CA  1 
ATOM   6085 C  C   . GLY B 1 289 ? 57.39073  -1.09022  -70.70854 1.000 74.32300  ? 289 GLY B C   1 
ATOM   6086 O  O   . GLY B 1 289 ? 56.64425  -0.58423  -69.87476 1.000 75.13436  ? 289 GLY B O   1 
ATOM   6087 N  N   . ALA B 1 290 ? 57.39716  -2.38915  -71.00917 1.000 64.15972  ? 290 ALA B N   1 
ATOM   6088 C  CA  . ALA B 1 290 ? 56.50833  -3.35384  -70.37968 1.000 65.22769  ? 290 ALA B CA  1 
ATOM   6089 C  C   . ALA B 1 290 ? 57.25118  -4.66191  -70.14929 1.000 71.40565  ? 290 ALA B C   1 
ATOM   6090 O  O   . ALA B 1 290 ? 58.19265  -4.99425  -70.87468 1.000 63.16752  ? 290 ALA B O   1 
ATOM   6091 C  CB  . ALA B 1 290 ? 55.26329  -3.61415  -71.23376 1.000 57.71069  ? 290 ALA B CB  1 
ATOM   6092 N  N   . LYS B 1 291 ? 56.81108  -5.40444  -69.13248 1.000 78.70210  ? 291 LYS B N   1 
ATOM   6093 C  CA  . LYS B 1 291 ? 57.35794  -6.71736  -68.81626 1.000 75.42016  ? 291 LYS B CA  1 
ATOM   6094 C  C   . LYS B 1 291 ? 56.22092  -7.61998  -68.34992 1.000 76.01072  ? 291 LYS B C   1 
ATOM   6095 O  O   . LYS B 1 291 ? 55.19205  -7.14696  -67.86039 1.000 76.70814  ? 291 LYS B O   1 
ATOM   6096 C  CB  . LYS B 1 291 ? 58.47283  -6.62684  -67.75749 1.000 62.92006  ? 291 LYS B CB  1 
ATOM   6097 C  CG  . LYS B 1 291 ? 59.66022  -5.75596  -68.17603 1.000 59.86700  ? 291 LYS B CG  1 
ATOM   6098 C  CD  . LYS B 1 291 ? 60.82384  -5.84773  -67.20203 1.000 63.61013  ? 291 LYS B CD  1 
ATOM   6099 C  CE  . LYS B 1 291 ? 61.93776  -4.87408  -67.57086 1.000 68.63061  ? 291 LYS B CE  1 
ATOM   6100 N  NZ  . LYS B 1 291 ? 62.44584  -5.08367  -68.95461 1.000 68.19967  ? 291 LYS B NZ  1 
ATOM   6101 N  N   . ILE B 1 292 ? 56.41568  -8.93174  -68.50198 1.000 75.47464  ? 292 ILE B N   1 
ATOM   6102 C  CA  . ILE B 1 292 ? 55.32618  -9.89717  -68.41096 1.000 72.71185  ? 292 ILE B CA  1 
ATOM   6103 C  C   . ILE B 1 292 ? 55.56977  -10.88009 -67.27222 1.000 73.72121  ? 292 ILE B C   1 
ATOM   6104 O  O   . ILE B 1 292 ? 56.70591  -11.27283 -66.98757 1.000 63.18655  ? 292 ILE B O   1 
ATOM   6105 C  CB  . ILE B 1 292 ? 55.14079  -10.64349 -69.75056 1.000 59.10971  ? 292 ILE B CB  1 
ATOM   6106 C  CG1 . ILE B 1 292 ? 54.78923  -9.65486  -70.85717 1.000 73.98363  ? 292 ILE B CG1 1 
ATOM   6107 C  CG2 . ILE B 1 292 ? 54.05390  -11.70537 -69.65087 1.000 60.82760  ? 292 ILE B CG2 1 
ATOM   6108 C  CD1 . ILE B 1 292 ? 53.49172  -8.91309  -70.61974 1.000 73.21383  ? 292 ILE B CD1 1 
ATOM   6109 N  N   . ILE B 1 293 ? 54.47514  -11.27369 -66.61807 1.000 64.99518  ? 293 ILE B N   1 
ATOM   6110 C  CA  . ILE B 1 293 ? 54.47261  -12.26609 -65.54913 1.000 60.09060  ? 293 ILE B CA  1 
ATOM   6111 C  C   . ILE B 1 293 ? 53.42845  -13.32567 -65.88393 1.000 75.80977  ? 293 ILE B C   1 
ATOM   6112 O  O   . ILE B 1 293 ? 52.27788  -12.99242 -66.18746 1.000 81.16934  ? 293 ILE B O   1 
ATOM   6113 C  CB  . ILE B 1 293 ? 54.17448  -11.62382 -64.18006 1.000 62.84867  ? 293 ILE B CB  1 
ATOM   6114 C  CG1 . ILE B 1 293 ? 55.17931  -10.50729 -63.88554 1.000 62.64446  ? 293 ILE B CG1 1 
ATOM   6115 C  CG2 . ILE B 1 293 ? 54.20378  -12.67180 -63.08243 1.000 76.16035  ? 293 ILE B CG2 1 
ATOM   6116 C  CD1 . ILE B 1 293 ? 54.86407  -9.71453  -62.63887 1.000 62.05613  ? 293 ILE B CD1 1 
ATOM   6117 N  N   . LEU B 1 294 ? 53.82747  -14.59620 -65.82934 1.000 67.85683  ? 294 LEU B N   1 
ATOM   6118 C  CA  . LEU B 1 294 ? 52.93384  -15.69867 -66.16709 1.000 60.12679  ? 294 LEU B CA  1 
ATOM   6119 C  C   . LEU B 1 294 ? 51.97222  -15.99013 -65.01935 1.000 64.99194  ? 294 LEU B C   1 
ATOM   6120 O  O   . LEU B 1 294 ? 52.35017  -15.93239 -63.84642 1.000 60.73673  ? 294 LEU B O   1 
ATOM   6121 C  CB  . LEU B 1 294 ? 53.74876  -16.94967 -66.50422 1.000 79.31869  ? 294 LEU B CB  1 
ATOM   6122 C  CG  . LEU B 1 294 ? 53.00198  -18.19888 -66.97586 1.000 82.42903  ? 294 LEU B CG  1 
ATOM   6123 C  CD1 . LEU B 1 294 ? 52.18845  -17.89788 -68.22393 1.000 76.31077  ? 294 LEU B CD1 1 
ATOM   6124 C  CD2 . LEU B 1 294 ? 53.97998  -19.33838 -67.23048 1.000 53.48316  ? 294 LEU B CD2 1 
ATOM   6125 N  N   . SER B 1 295 ? 50.72269  -16.31132 -65.36206 1.000 64.48030  ? 295 SER B N   1 
ATOM   6126 C  CA  . SER B 1 295 ? 49.67120  -16.51735 -64.37231 1.000 59.73935  ? 295 SER B CA  1 
ATOM   6127 C  C   . SER B 1 295 ? 49.00209  -17.86923 -64.57981 1.000 65.62969  ? 295 SER B C   1 
ATOM   6128 O  O   . SER B 1 295 ? 48.67112  -18.23815 -65.71131 1.000 75.38058  ? 295 SER B O   1 
ATOM   6129 C  CB  . SER B 1 295 ? 48.62108  -15.39971 -64.43424 1.000 70.19033  ? 295 SER B CB  1 
ATOM   6130 O  OG  . SER B 1 295 ? 47.66947  -15.64032 -65.45623 1.000 68.62741  ? 295 SER B OG  1 
ATOM   6131 N  N   . GLY B 1 296 ? 48.80740  -18.60002 -63.48309 1.000 70.98680  ? 296 GLY B N   1 
ATOM   6132 C  CA  . GLY B 1 296 ? 48.06348  -19.84568 -63.49035 1.000 70.77019  ? 296 GLY B CA  1 
ATOM   6133 C  C   . GLY B 1 296 ? 46.92379  -19.80428 -62.49291 1.000 68.14598  ? 296 GLY B C   1 
ATOM   6134 O  O   . GLY B 1 296 ? 46.95831  -19.00830 -61.55255 1.000 83.82768  ? 296 GLY B O   1 
ATOM   6135 N  N   . LEU B 1 297 ? 45.91354  -20.64700 -62.67386 1.000 59.05238  ? 297 LEU B N   1 
ATOM   6136 C  CA  . LEU B 1 297 ? 44.71319  -20.58654 -61.85222 1.000 55.54598  ? 297 LEU B CA  1 
ATOM   6137 C  C   . LEU B 1 297 ? 44.84870  -21.45831 -60.60846 1.000 64.44782  ? 297 LEU B C   1 
ATOM   6138 O  O   . LEU B 1 297 ? 45.57087  -22.45905 -60.59898 1.000 75.42127  ? 297 LEU B O   1 
ATOM   6139 C  CB  . LEU B 1 297 ? 43.49144  -21.00693 -62.67020 1.000 61.37260  ? 297 LEU B CB  1 
ATOM   6140 C  CG  . LEU B 1 297 ? 43.22333  -20.07433 -63.85383 1.000 55.37046  ? 297 LEU B CG  1 
ATOM   6141 C  CD1 . LEU B 1 297 ? 42.41603  -20.76366 -64.93935 1.000 54.98437  ? 297 LEU B CD1 1 
ATOM   6142 C  CD2 . LEU B 1 297 ? 42.51465  -18.81726 -63.37717 1.000 55.33830  ? 297 LEU B CD2 1 
ATOM   6143 N  N   . ARG B 1 298 ? 44.13635  -21.06351 -59.55168 1.000 75.37136  ? 298 ARG B N   1 
ATOM   6144 C  CA  . ARG B 1 298 ? 44.23497  -21.71573 -58.25080 1.000 66.55240  ? 298 ARG B CA  1 
ATOM   6145 C  C   . ARG B 1 298 ? 43.41024  -22.99122 -58.14300 1.000 60.98013  ? 298 ARG B C   1 
ATOM   6146 O  O   . ARG B 1 298 ? 43.43014  -23.62309 -57.08276 1.000 73.22901  ? 298 ARG B O   1 
ATOM   6147 C  CB  . ARG B 1 298 ? 43.81114  -20.75216 -57.13632 1.000 70.92865  ? 298 ARG B CB  1 
ATOM   6148 C  CG  . ARG B 1 298 ? 44.87020  -19.73560 -56.74462 1.000 79.61247  ? 298 ARG B CG  1 
ATOM   6149 C  CD  . ARG B 1 298 ? 44.38694  -18.84263 -55.61396 1.000 64.77142  ? 298 ARG B CD  1 
ATOM   6150 N  NE  . ARG B 1 298 ? 45.39513  -17.86351 -55.22849 1.000 70.25219  ? 298 ARG B NE  1 
ATOM   6151 C  CZ  . ARG B 1 298 ? 46.32887  -18.07203 -54.31004 1.000 82.03758  ? 298 ARG B CZ  1 
ATOM   6152 N  NH1 . ARG B 1 298 ? 46.40744  -19.21683 -53.65147 1.000 63.30042  ? 298 ARG B NH1 1 
ATOM   6153 N  NH2 . ARG B 1 298 ? 47.20741  -17.10828 -54.04734 1.000 82.61216  ? 298 ARG B NH2 1 
ATOM   6154 N  N   . PHE B 1 299 ? 42.67967  -23.38265 -59.18761 1.000 65.23527  ? 299 PHE B N   1 
ATOM   6155 C  CA  . PHE B 1 299 ? 41.83356  -24.56870 -59.13382 1.000 74.13272  ? 299 PHE B CA  1 
ATOM   6156 C  C   . PHE B 1 299 ? 42.30980  -25.67696 -60.06832 1.000 69.33508  ? 299 PHE B C   1 
ATOM   6157 O  O   . PHE B 1 299 ? 41.53864  -26.58806 -60.38573 1.000 63.84225  ? 299 PHE B O   1 
ATOM   6158 C  CB  . PHE B 1 299 ? 40.37803  -24.20174 -59.43607 1.000 64.61744  ? 299 PHE B CB  1 
ATOM   6159 C  CG  . PHE B 1 299 ? 40.20093  -23.30737 -60.63530 1.000 69.03313  ? 299 PHE B CG  1 
ATOM   6160 C  CD1 . PHE B 1 299 ? 40.18617  -21.92920 -60.49111 1.000 63.34421  ? 299 PHE B CD1 1 
ATOM   6161 C  CD2 . PHE B 1 299 ? 40.02071  -23.84421 -61.90065 1.000 81.43949  ? 299 PHE B CD2 1 
ATOM   6162 C  CE1 . PHE B 1 299 ? 40.01300  -21.10468 -61.58590 1.000 61.33153  ? 299 PHE B CE1 1 
ATOM   6163 C  CE2 . PHE B 1 299 ? 39.84652  -23.02280 -62.99918 1.000 72.95957  ? 299 PHE B CE2 1 
ATOM   6164 C  CZ  . PHE B 1 299 ? 39.84060  -21.65236 -62.83968 1.000 65.64411  ? 299 PHE B CZ  1 
ATOM   6165 N  N   . LYS B 1 300 ? 43.56233  -25.62677 -60.50910 1.000 68.87649  ? 300 LYS B N   1 
ATOM   6166 C  CA  . LYS B 1 300 ? 44.10978  -26.63044 -61.40856 1.000 79.58138  ? 300 LYS B CA  1 
ATOM   6167 C  C   . LYS B 1 300 ? 45.06226  -27.55820 -60.66102 1.000 79.67775  ? 300 LYS B C   1 
ATOM   6168 O  O   . LYS B 1 300 ? 45.62128  -27.20512 -59.62093 1.000 80.80779  ? 300 LYS B O   1 
ATOM   6169 C  CB  . LYS B 1 300 ? 44.81287  -25.96684 -62.59682 1.000 72.85437  ? 300 LYS B CB  1 
ATOM   6170 C  CG  . LYS B 1 300 ? 43.85537  -25.17255 -63.46973 1.000 57.57702  ? 300 LYS B CG  1 
ATOM   6171 C  CD  . LYS B 1 300 ? 44.41321  -24.91924 -64.85679 1.000 69.85061  ? 300 LYS B CD  1 
ATOM   6172 C  CE  . LYS B 1 300 ? 43.32836  -24.37096 -65.77092 1.000 55.32379  ? 300 LYS B CE  1 
ATOM   6173 N  NZ  . LYS B 1 300 ? 43.82388  -24.10934 -67.14730 1.000 61.74057  ? 300 LYS B NZ  1 
ATOM   6174 N  N   . SER B 1 301 ? 45.24532  -28.75744 -61.21169 1.000 81.25553  ? 301 SER B N   1 
ATOM   6175 C  CA  . SER B 1 301 ? 45.96553  -29.81334 -60.50954 1.000 76.04457  ? 301 SER B CA  1 
ATOM   6176 C  C   . SER B 1 301 ? 47.43491  -29.45285 -60.31787 1.000 69.19851  ? 301 SER B C   1 
ATOM   6177 O  O   . SER B 1 301 ? 48.00875  -28.65812 -61.06749 1.000 70.10508  ? 301 SER B O   1 
ATOM   6178 C  CB  . SER B 1 301 ? 45.85713  -31.13702 -61.26739 1.000 81.41348  ? 301 SER B CB  1 
ATOM   6179 O  OG  . SER B 1 301 ? 46.63103  -31.11040 -62.45241 1.000 80.49848  ? 301 SER B OG  1 
ATOM   6180 N  N   . GLN B 1 302 ? 48.03990  -30.04764 -59.28461 1.000 71.16172  ? 302 GLN B N   1 
ATOM   6181 C  CA  . GLN B 1 302 ? 49.45925  -29.83013 -59.02522 1.000 75.15467  ? 302 GLN B CA  1 
ATOM   6182 C  C   . GLN B 1 302 ? 50.31425  -30.21545 -60.22401 1.000 83.74358  ? 302 GLN B C   1 
ATOM   6183 O  O   . GLN B 1 302 ? 51.38527  -29.63489 -60.43561 1.000 87.20668  ? 302 GLN B O   1 
ATOM   6184 C  CB  . GLN B 1 302 ? 49.89565  -30.62537 -57.79448 1.000 66.19009  ? 302 GLN B CB  1 
ATOM   6185 C  CG  . GLN B 1 302 ? 49.06409  -30.36458 -56.54962 1.000 70.52370  ? 302 GLN B CG  1 
ATOM   6186 C  CD  . GLN B 1 302 ? 49.33174  -31.37911 -55.45359 1.000 74.79825  ? 302 GLN B CD  1 
ATOM   6187 O  OE1 . GLN B 1 302 ? 48.63657  -32.38977 -55.34498 1.000 67.34778  ? 302 GLN B OE1 1 
ATOM   6188 N  NE2 . GLN B 1 302 ? 50.34879  -31.11891 -54.64010 1.000 73.95334  ? 302 GLN B NE2 1 
ATOM   6189 N  N   . GLU B 1 303 ? 49.86677  -31.19634 -61.01029 1.000 85.04017  ? 303 GLU B N   1 
ATOM   6190 C  CA  . GLU B 1 303 ? 50.58983  -31.56907 -62.22165 1.000 77.56876  ? 303 GLU B CA  1 
ATOM   6191 C  C   . GLU B 1 303 ? 50.60688  -30.42322 -63.22681 1.000 86.66246  ? 303 GLU B C   1 
ATOM   6192 O  O   . GLU B 1 303 ? 51.66037  -30.07887 -63.77550 1.000 90.47243  ? 303 GLU B O   1 
ATOM   6193 C  CB  . GLU B 1 303 ? 49.96153  -32.82050 -62.83497 1.000 98.68819  ? 303 GLU B CB  1 
ATOM   6194 C  CG  . GLU B 1 303 ? 50.64758  -33.31662 -64.09522 1.000 101.73059 ? 303 GLU B CG  1 
ATOM   6195 C  CD  . GLU B 1 303 ? 50.09282  -34.64651 -64.56834 1.000 110.42179 ? 303 GLU B CD  1 
ATOM   6196 O  OE1 . GLU B 1 303 ? 49.14421  -35.15543 -63.93395 1.000 94.18190  ? 303 GLU B OE1 1 
ATOM   6197 O  OE2 . GLU B 1 303 ? 50.60688  -35.18402 -65.57154 1.000 119.77051 ? 303 GLU B OE2 1 
ATOM   6198 N  N   . GLU B 1 304 ? 49.44196  -29.81830 -63.47932 1.000 86.84454  ? 304 GLU B N   1 
ATOM   6199 C  CA  . GLU B 1 304 ? 49.36981  -28.71475 -64.43321 1.000 83.21122  ? 304 GLU B CA  1 
ATOM   6200 C  C   . GLU B 1 304 ? 50.20549  -27.52829 -63.97066 1.000 73.77643  ? 304 GLU B C   1 
ATOM   6201 O  O   . GLU B 1 304 ? 50.90186  -26.89759 -64.77545 1.000 83.83510  ? 304 GLU B O   1 
ATOM   6202 C  CB  . GLU B 1 304 ? 47.91576  -28.29044 -64.63857 1.000 86.70195  ? 304 GLU B CB  1 
ATOM   6203 C  CG  . GLU B 1 304 ? 46.98748  -29.41769 -65.05368 1.000 93.86449  ? 304 GLU B CG  1 
ATOM   6204 C  CD  . GLU B 1 304 ? 45.52879  -29.00018 -65.05374 1.000 95.03070  ? 304 GLU B CD  1 
ATOM   6205 O  OE1 . GLU B 1 304 ? 45.14833  -28.15954 -65.89647 1.000 109.33510 ? 304 GLU B OE1 1 
ATOM   6206 O  OE2 . GLU B 1 304 ? 44.76542  -29.50416 -64.20174 1.000 63.91473  ? 304 GLU B OE2 1 
ATOM   6207 N  N   . ILE B 1 305 ? 50.14490  -27.20728 -62.67599 1.000 73.98606  ? 305 ILE B N   1 
ATOM   6208 C  CA  . ILE B 1 305 ? 50.89446  -26.07010 -62.15421 1.000 72.49218  ? 305 ILE B CA  1 
ATOM   6209 C  C   . ILE B 1 305 ? 52.39438  -26.32807 -62.23644 1.000 72.13499  ? 305 ILE B C   1 
ATOM   6210 O  O   . ILE B 1 305 ? 53.17826  -25.39636 -62.45535 1.000 73.30666  ? 305 ILE B O   1 
ATOM   6211 C  CB  . ILE B 1 305 ? 50.44271  -25.74919 -60.71673 1.000 74.15064  ? 305 ILE B CB  1 
ATOM   6212 C  CG1 . ILE B 1 305 ? 48.92842  -25.53141 -60.67039 1.000 70.25158  ? 305 ILE B CG1 1 
ATOM   6213 C  CG2 . ILE B 1 305 ? 51.15260  -24.51510 -60.19112 1.000 71.77160  ? 305 ILE B CG2 1 
ATOM   6214 C  CD1 . ILE B 1 305 ? 48.41543  -24.53874 -61.69387 1.000 71.51480  ? 305 ILE B CD1 1 
ATOM   6215 N  N   . LEU B 1 306 ? 52.82093  -27.58456 -62.07230 1.000 73.57218  ? 306 LEU B N   1 
ATOM   6216 C  CA  . LEU B 1 306 ? 54.23924  -27.90770 -62.20768 1.000 76.04974  ? 306 LEU B CA  1 
ATOM   6217 C  C   . LEU B 1 306 ? 54.73930  -27.64856 -63.62356 1.000 79.02671  ? 306 LEU B C   1 
ATOM   6218 O  O   . LEU B 1 306 ? 55.83356  -27.10245 -63.80845 1.000 76.91745  ? 306 LEU B O   1 
ATOM   6219 C  CB  . LEU B 1 306 ? 54.49348  -29.36359 -61.81658 1.000 68.11221  ? 306 LEU B CB  1 
ATOM   6220 C  CG  . LEU B 1 306 ? 55.93413  -29.83776 -62.03052 1.000 66.93397  ? 306 LEU B CG  1 
ATOM   6221 C  CD1 . LEU B 1 306 ? 56.91847  -28.95229 -61.27221 1.000 61.18401  ? 306 LEU B CD1 1 
ATOM   6222 C  CD2 . LEU B 1 306 ? 56.09349  -31.29558 -61.62765 1.000 64.89091  ? 306 LEU B CD2 1 
ATOM   6223 N  N   . ASN B 1 307 ? 53.95905  -28.03606 -64.63498 1.000 81.59820  ? 307 ASN B N   1 
ATOM   6224 C  CA  . ASN B 1 307 ? 54.36393  -27.77030 -66.01120 1.000 84.03421  ? 307 ASN B CA  1 
ATOM   6225 C  C   . ASN B 1 307 ? 54.48175  -26.27328 -66.26519 1.000 78.31205  ? 307 ASN B C   1 
ATOM   6226 O  O   . ASN B 1 307 ? 55.39326  -25.82453 -66.96917 1.000 79.46878  ? 307 ASN B O   1 
ATOM   6227 C  CB  . ASN B 1 307 ? 53.37642  -28.41149 -66.98654 1.000 86.15658  ? 307 ASN B CB  1 
ATOM   6228 C  CG  . ASN B 1 307 ? 53.64474  -28.02280 -68.43070 1.000 104.29440 ? 307 ASN B CG  1 
ATOM   6229 O  OD1 . ASN B 1 307 ? 52.93996  -27.18873 -68.99951 1.000 103.33453 ? 307 ASN B OD1 1 
ATOM   6230 N  ND2 . ASN B 1 307 ? 54.67251  -28.61979 -69.02765 1.000 95.54320  ? 307 ASN B ND2 1 
ATOM   6231 N  N   . GLU B 1 308 ? 53.56929  -25.48383 -65.69469 1.000 75.91632  ? 308 GLU B N   1 
ATOM   6232 C  CA  . GLU B 1 308 ? 53.63661  -24.03493 -65.85643 1.000 72.99023  ? 308 GLU B CA  1 
ATOM   6233 C  C   . GLU B 1 308 ? 54.87734  -23.45688 -65.18558 1.000 66.80682  ? 308 GLU B C   1 
ATOM   6234 O  O   . GLU B 1 308 ? 55.49102  -22.51721 -65.70637 1.000 76.45206  ? 308 GLU B O   1 
ATOM   6235 C  CB  . GLU B 1 308 ? 52.36422  -23.39038 -65.30585 1.000 60.66756  ? 308 GLU B CB  1 
ATOM   6236 C  CG  . GLU B 1 308 ? 51.09788  -23.89122 -65.98694 1.000 70.31431  ? 308 GLU B CG  1 
ATOM   6237 C  CD  . GLU B 1 308 ? 49.84716  -23.16494 -65.53302 1.000 66.83593  ? 308 GLU B CD  1 
ATOM   6238 O  OE1 . GLU B 1 308 ? 49.95781  -22.25735 -64.68513 1.000 76.09510  ? 308 GLU B OE1 1 
ATOM   6239 O  OE2 . GLU B 1 308 ? 48.75095  -23.50188 -66.02941 1.000 60.46519  ? 308 GLU B OE2 1 
ATOM   6240 N  N   . VAL B 1 309 ? 55.25796  -23.99891 -64.02455 1.000 62.52282  ? 309 VAL B N   1 
ATOM   6241 C  CA  . VAL B 1 309 ? 56.48392  -23.55693 -63.36369 1.000 69.42898  ? 309 VAL B CA  1 
ATOM   6242 C  C   . VAL B 1 309 ? 57.70043  -23.85895 -64.23386 1.000 72.78313  ? 309 VAL B C   1 
ATOM   6243 O  O   . VAL B 1 309 ? 58.64896  -23.06708 -64.29582 1.000 76.40371  ? 309 VAL B O   1 
ATOM   6244 C  CB  . VAL B 1 309 ? 56.60392  -24.20157 -61.96913 1.000 61.20426  ? 309 VAL B CB  1 
ATOM   6245 C  CG1 . VAL B 1 309 ? 57.94082  -23.85464 -61.33539 1.000 55.68208  ? 309 VAL B CG1 1 
ATOM   6246 C  CG2 . VAL B 1 309 ? 55.46714  -23.73724 -61.07525 1.000 61.71463  ? 309 VAL B CG2 1 
ATOM   6247 N  N   . LYS B 1 310 ? 57.69425  -25.00314 -64.92342 1.000 76.64618  ? 310 LYS B N   1 
ATOM   6248 C  CA  . LYS B 1 310 ? 58.83312  -25.35783 -65.76711 1.000 85.02327  ? 310 LYS B CA  1 
ATOM   6249 C  C   . LYS B 1 310 ? 58.91866  -24.46295 -66.99842 1.000 78.76676  ? 310 LYS B C   1 
ATOM   6250 O  O   . LYS B 1 310 ? 60.01285  -24.03310 -67.38470 1.000 78.09918  ? 310 LYS B O   1 
ATOM   6251 C  CB  . LYS B 1 310 ? 58.75257  -26.82748 -66.17654 1.000 81.85395  ? 310 LYS B CB  1 
ATOM   6252 C  CG  . LYS B 1 310 ? 58.93958  -27.79961 -65.02685 1.000 75.85441  ? 310 LYS B CG  1 
ATOM   6253 C  CD  . LYS B 1 310 ? 58.91084  -29.23604 -65.51319 1.000 71.50086  ? 310 LYS B CD  1 
ATOM   6254 C  CE  . LYS B 1 310 ? 59.25735  -30.19487 -64.39004 1.000 86.67216  ? 310 LYS B CE  1 
ATOM   6255 N  NZ  . LYS B 1 310 ? 59.40389  -31.58833 -64.88754 1.000 98.64562  ? 310 LYS B NZ  1 
ATOM   6256 N  N   . ILE B 1 311 ? 57.77753  -24.17700 -67.63225 1.000 69.70539  ? 311 ILE B N   1 
ATOM   6257 C  CA  . ILE B 1 311 ? 57.76619  -23.25881 -68.76921 1.000 69.55047  ? 311 ILE B CA  1 
ATOM   6258 C  C   . ILE B 1 311 ? 58.25467  -21.88171 -68.34339 1.000 78.52820  ? 311 ILE B C   1 
ATOM   6259 O  O   . ILE B 1 311 ? 58.91733  -21.18013 -69.11866 1.000 76.99780  ? 311 ILE B O   1 
ATOM   6260 C  CB  . ILE B 1 311 ? 56.35491  -23.18883 -69.39023 1.000 58.21831  ? 311 ILE B CB  1 
ATOM   6261 C  CG1 . ILE B 1 311 ? 55.88424  -24.57209 -69.82966 1.000 62.86335  ? 311 ILE B CG1 1 
ATOM   6262 C  CG2 . ILE B 1 311 ? 56.34282  -22.26814 -70.59503 1.000 65.01032  ? 311 ILE B CG2 1 
ATOM   6263 C  CD1 . ILE B 1 311 ? 54.45752  -24.58356 -70.32933 1.000 66.40877  ? 311 ILE B CD1 1 
ATOM   6264 N  N   . ALA B 1 312 ? 57.94308  -21.47338 -67.11116 1.000 74.43796  ? 312 ALA B N   1 
ATOM   6265 C  CA  . ALA B 1 312 ? 58.36984  -20.16492 -66.62609 1.000 71.00448  ? 312 ALA B CA  1 
ATOM   6266 C  C   . ALA B 1 312 ? 59.87896  -20.10598 -66.41711 1.000 75.99288  ? 312 ALA B C   1 
ATOM   6267 O  O   . ALA B 1 312 ? 60.50144  -19.06706 -66.66492 1.000 75.30001  ? 312 ALA B O   1 
ATOM   6268 C  CB  . ALA B 1 312 ? 57.63634  -19.82532 -65.32889 1.000 73.06322  ? 312 ALA B CB  1 
ATOM   6269 N  N   . MET B 1 313 ? 60.48360  -21.20119 -65.94786 1.000 70.84741  ? 313 MET B N   1 
ATOM   6270 C  CA  . MET B 1 313 ? 61.93099  -21.21885 -65.75084 1.000 70.91712  ? 313 MET B CA  1 
ATOM   6271 C  C   . MET B 1 313 ? 62.66793  -21.01599 -67.06840 1.000 89.60278  ? 313 MET B C   1 
ATOM   6272 O  O   . MET B 1 313 ? 63.62469  -20.23612 -67.14717 1.000 87.02059  ? 313 MET B O   1 
ATOM   6273 C  CB  . MET B 1 313 ? 62.36344  -22.53523 -65.10399 1.000 74.73286  ? 313 MET B CB  1 
ATOM   6274 C  CG  . MET B 1 313 ? 61.95592  -22.70024 -63.65475 1.000 82.53212  ? 313 MET B CG  1 
ATOM   6275 S  SD  . MET B 1 313 ? 62.57533  -24.24855 -62.96876 1.000 77.92088  ? 313 MET B SD  1 
ATOM   6276 C  CE  . MET B 1 313 ? 64.32347  -24.11568 -63.33851 1.000 76.83902  ? 313 MET B CE  1 
ATOM   6277 N  N   . ASP B 1 314 ? 62.23509  -21.71735 -68.11762 1.000 91.91953  ? 314 ASP B N   1 
ATOM   6278 C  CA  . ASP B 1 314 ? 62.90969  -21.61500 -69.40754 1.000 82.97945  ? 314 ASP B CA  1 
ATOM   6279 C  C   . ASP B 1 314 ? 62.66907  -20.25883 -70.05717 1.000 82.02528  ? 314 ASP B C   1 
ATOM   6280 O  O   . ASP B 1 314 ? 63.58232  -19.68719 -70.66385 1.000 84.73408  ? 314 ASP B O   1 
ATOM   6281 C  CB  . ASP B 1 314 ? 62.45172  -22.74666 -70.32587 1.000 88.64834  ? 314 ASP B CB  1 
ATOM   6282 C  CG  . ASP B 1 314 ? 62.88786  -24.11088 -69.82613 1.000 94.54195  ? 314 ASP B CG  1 
ATOM   6283 O  OD1 . ASP B 1 314 ? 63.98054  -24.20364 -69.22665 1.000 95.73049  ? 314 ASP B OD1 1 
ATOM   6284 O  OD2 . ASP B 1 314 ? 62.13534  -25.08854 -70.02352 1.000 88.02603  ? 314 ASP B OD2 1 
ATOM   6285 N  N   . LEU B 1 315 ? 61.44457  -19.73376 -69.95565 1.000 85.00240  ? 315 LEU B N   1 
ATOM   6286 C  CA  . LEU B 1 315 ? 61.16826  -18.41066 -70.50631 1.000 83.19581  ? 315 LEU B CA  1 
ATOM   6287 C  C   . LEU B 1 315 ? 61.99326  -17.33467 -69.81620 1.000 78.48321  ? 315 LEU B C   1 
ATOM   6288 O  O   . LEU B 1 315 ? 62.36530  -16.33866 -70.44722 1.000 82.24516  ? 315 LEU B O   1 
ATOM   6289 C  CB  . LEU B 1 315 ? 59.67818  -18.08489 -70.39796 1.000 68.16854  ? 315 LEU B CB  1 
ATOM   6290 C  CG  . LEU B 1 315 ? 58.75979  -18.70934 -71.45017 1.000 67.72016  ? 315 LEU B CG  1 
ATOM   6291 C  CD1 . LEU B 1 315 ? 57.36202  -18.11297 -71.36662 1.000 70.87024  ? 315 LEU B CD1 1 
ATOM   6292 C  CD2 . LEU B 1 315 ? 59.33984  -18.53272 -72.84684 1.000 63.37028  ? 315 LEU B CD2 1 
ATOM   6293 N  N   . HIS B 1 316 ? 62.28153  -17.51086 -68.52493 1.000 72.02393  ? 316 HIS B N   1 
ATOM   6294 C  CA  . HIS B 1 316 ? 63.12012  -16.54828 -67.81994 1.000 80.02452  ? 316 HIS B CA  1 
ATOM   6295 C  C   . HIS B 1 316 ? 64.53660  -16.53141 -68.38523 1.000 84.89414  ? 316 HIS B C   1 
ATOM   6296 O  O   . HIS B 1 316 ? 65.12957  -15.46051 -68.55938 1.000 89.90730  ? 316 HIS B O   1 
ATOM   6297 C  CB  . HIS B 1 316 ? 63.13653  -16.86564 -66.32498 1.000 86.63291  ? 316 HIS B CB  1 
ATOM   6298 C  CG  . HIS B 1 316 ? 63.72215  -15.77546 -65.48311 1.000 87.37773  ? 316 HIS B CG  1 
ATOM   6299 N  ND1 . HIS B 1 316 ? 64.49355  -16.02825 -64.36964 1.000 76.79752  ? 316 HIS B ND1 1 
ATOM   6300 C  CD2 . HIS B 1 316 ? 63.64574  -14.42770 -65.58948 1.000 84.42680  ? 316 HIS B CD2 1 
ATOM   6301 C  CE1 . HIS B 1 316 ? 64.87084  -14.88361 -63.82867 1.000 78.47223  ? 316 HIS B CE1 1 
ATOM   6302 N  NE2 . HIS B 1 316 ? 64.36854  -13.89692 -64.54871 1.000 82.18776  ? 316 HIS B NE2 1 
ATOM   6303 N  N   . LYS B 1 317 ? 65.09894  -17.70900 -68.67427 1.000 75.76242  ? 317 LYS B N   1 
ATOM   6304 C  CA  . LYS B 1 317 ? 66.43277  -17.76506 -69.26739 1.000 72.95261  ? 317 LYS B CA  1 
ATOM   6305 C  C   . LYS B 1 317 ? 66.42091  -17.24144 -70.69826 1.000 79.31470  ? 317 LYS B C   1 
ATOM   6306 O  O   . LYS B 1 317 ? 67.25336  -16.40774 -71.07451 1.000 71.17712  ? 317 LYS B O   1 
ATOM   6307 C  CB  . LYS B 1 317 ? 66.96756  -19.19767 -69.24650 1.000 72.01558  ? 317 LYS B CB  1 
ATOM   6308 C  CG  . LYS B 1 317 ? 66.85166  -19.92865 -67.92424 1.000 93.59850  ? 317 LYS B CG  1 
ATOM   6309 C  CD  . LYS B 1 317 ? 67.29214  -21.37586 -68.09609 1.000 104.60276 ? 317 LYS B CD  1 
ATOM   6310 C  CE  . LYS B 1 317 ? 67.03055  -22.20280 -66.85114 1.000 105.64093 ? 317 LYS B CE  1 
ATOM   6311 N  NZ  . LYS B 1 317 ? 67.31732  -23.64472 -67.09136 1.000 84.28210  ? 317 LYS B NZ  1 
ATOM   6312 N  N   . LYS B 1 318 ? 65.47871  -17.72734 -71.51075 1.000 84.86633  ? 318 LYS B N   1 
ATOM   6313 C  CA  . LYS B 1 318 ? 65.45005  -17.38133 -72.92907 1.000 80.53796  ? 318 LYS B CA  1 
ATOM   6314 C  C   . LYS B 1 318 ? 65.21177  -15.89241 -73.13435 1.000 78.73211  ? 318 LYS B C   1 
ATOM   6315 O  O   . LYS B 1 318 ? 65.83196  -15.26964 -74.00451 1.000 89.69759  ? 318 LYS B O   1 
ATOM   6316 C  CB  . LYS B 1 318 ? 64.36927  -18.19671 -73.63751 1.000 74.33522  ? 318 LYS B CB  1 
ATOM   6317 C  CG  . LYS B 1 318 ? 64.83083  -18.89791 -74.90083 1.000 81.25486  ? 318 LYS B CG  1 
ATOM   6318 C  CD  . LYS B 1 318 ? 63.77341  -19.87947 -75.37633 1.000 85.56032  ? 318 LYS B CD  1 
ATOM   6319 C  CE  . LYS B 1 318 ? 64.33106  -20.84240 -76.40679 1.000 75.40524  ? 318 LYS B CE  1 
ATOM   6320 N  NZ  . LYS B 1 318 ? 63.42093  -22.00222 -76.61306 1.000 63.65566  ? 318 LYS B NZ  1 
ATOM   6321 N  N   . TYR B 1 319 ? 64.31562  -15.30432 -72.34255 1.000 73.29164  ? 319 TYR B N   1 
ATOM   6322 C  CA  . TYR B 1 319 ? 63.95178  -13.89514 -72.44671 1.000 81.79587  ? 319 TYR B CA  1 
ATOM   6323 C  C   . TYR B 1 319 ? 64.23542  -13.26302 -71.08978 1.000 85.38589  ? 319 TYR B C   1 
ATOM   6324 O  O   . TYR B 1 319 ? 63.32416  -13.07677 -70.26936 1.000 78.54240  ? 319 TYR B O   1 
ATOM   6325 C  CB  . TYR B 1 319 ? 62.49485  -13.73380 -72.87297 1.000 65.58264  ? 319 TYR B CB  1 
ATOM   6326 C  CG  . TYR B 1 319 ? 62.18955  -14.45308 -74.16731 1.000 69.95397  ? 319 TYR B CG  1 
ATOM   6327 C  CD1 . TYR B 1 319 ? 62.40980  -13.83632 -75.39150 1.000 76.17338  ? 319 TYR B CD1 1 
ATOM   6328 C  CD2 . TYR B 1 319 ? 61.70348  -15.75375 -74.16791 1.000 68.54446  ? 319 TYR B CD2 1 
ATOM   6329 C  CE1 . TYR B 1 319 ? 62.14346  -14.48763 -76.57901 1.000 70.06354  ? 319 TYR B CE1 1 
ATOM   6330 C  CE2 . TYR B 1 319 ? 61.43295  -16.41457 -75.35215 1.000 76.20654  ? 319 TYR B CE2 1 
ATOM   6331 C  CZ  . TYR B 1 319 ? 61.65571  -15.77485 -76.55515 1.000 80.84345  ? 319 TYR B CZ  1 
ATOM   6332 O  OH  . TYR B 1 319 ? 61.39212  -16.42141 -77.74029 1.000 94.05713  ? 319 TYR B OH  1 
ATOM   6333 N  N   . PRO B 1 320 ? 65.49999  -12.92986 -70.81619 1.000 86.36853  ? 320 PRO B N   1 
ATOM   6334 C  CA  . PRO B 1 320 ? 65.85663  -12.46661 -69.46867 1.000 79.90295  ? 320 PRO B CA  1 
ATOM   6335 C  C   . PRO B 1 320 ? 65.32268  -11.08667 -69.14675 1.000 90.35492  ? 320 PRO B C   1 
ATOM   6336 O  O   . PRO B 1 320 ? 65.12671  -10.77109 -67.96774 1.000 93.54521  ? 320 PRO B O   1 
ATOM   6337 C  CB  . PRO B 1 320 ? 67.38981  -12.48831 -69.49011 1.000 81.19594  ? 320 PRO B CB  1 
ATOM   6338 C  CG  . PRO B 1 320 ? 67.73228  -12.23835 -70.92655 1.000 88.50534  ? 320 PRO B CG  1 
ATOM   6339 C  CD  . PRO B 1 320 ? 66.65107  -12.91044 -71.73652 1.000 77.90203  ? 320 PRO B CD  1 
ATOM   6340 N  N   . ASP B 1 321 ? 65.07584  -10.25253 -70.15178 1.000 83.08700  ? 321 ASP B N   1 
ATOM   6341 C  CA  . ASP B 1 321 ? 64.61435  -8.89366  -69.89918 1.000 75.67325  ? 321 ASP B CA  1 
ATOM   6342 C  C   . ASP B 1 321 ? 63.10007  -8.76355  -69.92602 1.000 76.34037  ? 321 ASP B C   1 
ATOM   6343 O  O   . ASP B 1 321 ? 62.54391  -7.96547  -69.16541 1.000 89.83814  ? 321 ASP B O   1 
ATOM   6344 C  CB  . ASP B 1 321 ? 65.22693  -7.93046  -70.92068 1.000 92.18867  ? 321 ASP B CB  1 
ATOM   6345 C  CG  . ASP B 1 321 ? 66.68145  -7.61955  -70.62896 1.000 103.91240 ? 321 ASP B CG  1 
ATOM   6346 O  OD1 . ASP B 1 321 ? 67.23290  -8.17647  -69.65396 1.000 102.49124 ? 321 ASP B OD1 1 
ATOM   6347 O  OD2 . ASP B 1 321 ? 67.27021  -6.81079  -71.37380 1.000 106.04099 ? 321 ASP B OD2 1 
ATOM   6348 N  N   . PHE B 1 322 ? 62.41711  -9.52787  -70.77696 1.000 80.26221  ? 322 PHE B N   1 
ATOM   6349 C  CA  . PHE B 1 322 ? 60.97538  -9.37888  -70.92078 1.000 73.51861  ? 322 PHE B CA  1 
ATOM   6350 C  C   . PHE B 1 322 ? 60.18116  -10.27977 -69.98443 1.000 72.38009  ? 322 PHE B C   1 
ATOM   6351 O  O   . PHE B 1 322 ? 59.04073  -9.94589  -69.64261 1.000 75.44467  ? 322 PHE B O   1 
ATOM   6352 C  CB  . PHE B 1 322 ? 60.56052  -9.64800  -72.37024 1.000 64.11988  ? 322 PHE B CB  1 
ATOM   6353 C  CG  . PHE B 1 322 ? 59.17855  -9.16312  -72.70289 1.000 64.09517  ? 322 PHE B CG  1 
ATOM   6354 C  CD1 . PHE B 1 322 ? 58.79784  -7.86615  -72.40089 1.000 66.74626  ? 322 PHE B CD1 1 
ATOM   6355 C  CD2 . PHE B 1 322 ? 58.26645  -9.99457  -73.32875 1.000 66.26543  ? 322 PHE B CD2 1 
ATOM   6356 C  CE1 . PHE B 1 322 ? 57.53017  -7.41248  -72.70719 1.000 70.19382  ? 322 PHE B CE1 1 
ATOM   6357 C  CE2 . PHE B 1 322 ? 56.99666  -9.54542  -73.63852 1.000 66.72225  ? 322 PHE B CE2 1 
ATOM   6358 C  CZ  . PHE B 1 322 ? 56.63044  -8.25013  -73.32962 1.000 66.15475  ? 322 PHE B CZ  1 
ATOM   6359 N  N   . PHE B 1 323 ? 60.74646  -11.40272 -69.55284 1.000 64.70504  ? 323 PHE B N   1 
ATOM   6360 C  CA  . PHE B 1 323 ? 60.04659  -12.33752 -68.68207 1.000 76.42498  ? 323 PHE B CA  1 
ATOM   6361 C  C   . PHE B 1 323 ? 60.56431  -12.19217 -67.25811 1.000 80.35509  ? 323 PHE B C   1 
ATOM   6362 O  O   . PHE B 1 323 ? 61.78002  -12.15429 -67.03219 1.000 75.49364  ? 323 PHE B O   1 
ATOM   6363 C  CB  . PHE B 1 323 ? 60.21517  -13.77759 -69.16727 1.000 64.88904  ? 323 PHE B CB  1 
ATOM   6364 C  CG  . PHE B 1 323 ? 59.25941  -14.74123 -68.52814 1.000 73.01436  ? 323 PHE B CG  1 
ATOM   6365 C  CD1 . PHE B 1 323 ? 57.98261  -14.91088 -69.03801 1.000 70.29186  ? 323 PHE B CD1 1 
ATOM   6366 C  CD2 . PHE B 1 323 ? 59.63374  -15.47334 -67.41410 1.000 74.58067  ? 323 PHE B CD2 1 
ATOM   6367 C  CE1 . PHE B 1 323 ? 57.09802  -15.79630 -68.45090 1.000 69.47106  ? 323 PHE B CE1 1 
ATOM   6368 C  CE2 . PHE B 1 323 ? 58.75451  -16.35994 -66.82237 1.000 68.05559  ? 323 PHE B CE2 1 
ATOM   6369 C  CZ  . PHE B 1 323 ? 57.48482  -16.52168 -67.34131 1.000 61.60304  ? 323 PHE B CZ  1 
ATOM   6370 N  N   . LEU B 1 324 ? 59.63782  -12.11374 -66.30392 1.000 70.54650  ? 324 LEU B N   1 
ATOM   6371 C  CA  . LEU B 1 324 ? 59.96904  -11.84969 -64.91039 1.000 77.57924  ? 324 LEU B CA  1 
ATOM   6372 C  C   . LEU B 1 324 ? 59.77192  -13.06228 -64.01052 1.000 80.59579  ? 324 LEU B C   1 
ATOM   6373 O  O   . LEU B 1 324 ? 60.69324  -13.44000 -63.27404 1.000 75.03887  ? 324 LEU B O   1 
ATOM   6374 C  CB  . LEU B 1 324 ? 59.12123  -10.68675 -64.38574 1.000 68.79430  ? 324 LEU B CB  1 
ATOM   6375 C  CG  . LEU B 1 324 ? 59.23028  -9.39515  -65.19485 1.000 71.37068  ? 324 LEU B CG  1 
ATOM   6376 C  CD1 . LEU B 1 324 ? 58.30560  -8.33546  -64.61926 1.000 71.97176  ? 324 LEU B CD1 1 
ATOM   6377 C  CD2 . LEU B 1 324 ? 60.67092  -8.91783  -65.21166 1.000 72.91565  ? 324 LEU B CD2 1 
ATOM   6378 N  N   . GLY B 1 325 ? 58.58763  -13.69006 -64.03658 1.000 62.59166  ? 325 GLY B N   1 
ATOM   6379 C  CA  . GLY B 1 325 ? 58.31522  -14.79427 -63.14530 1.000 60.68269  ? 325 GLY B CA  1 
ATOM   6380 C  C   . GLY B 1 325 ? 56.92041  -15.38592 -63.24199 1.000 72.68231  ? 325 GLY B C   1 
ATOM   6381 O  O   . GLY B 1 325 ? 56.27146  -15.32704 -64.29143 1.000 75.62757  ? 325 GLY B O   1 
ATOM   6382 N  N   . TYR B 1 326 ? 56.45085  -15.96882 -62.13911 1.000 70.88957  ? 326 TYR B N   1 
ATOM   6383 C  CA  . TYR B 1 326 ? 55.20975  -16.72482 -62.14000 1.000 71.63415  ? 326 TYR B CA  1 
ATOM   6384 C  C   . TYR B 1 326 ? 54.33166  -16.30128 -60.97031 1.000 70.59612  ? 326 TYR B C   1 
ATOM   6385 O  O   . TYR B 1 326 ? 54.82135  -15.85003 -59.93046 1.000 68.52235  ? 326 TYR B O   1 
ATOM   6386 C  CB  . TYR B 1 326 ? 55.49733  -18.23066 -62.08279 1.000 69.65626  ? 326 TYR B CB  1 
ATOM   6387 C  CG  . TYR B 1 326 ? 54.26330  -19.09615 -62.13376 1.000 69.17132  ? 326 TYR B CG  1 
ATOM   6388 C  CD1 . TYR B 1 326 ? 53.54351  -19.24911 -63.31130 1.000 69.39548  ? 326 TYR B CD1 1 
ATOM   6389 C  CD2 . TYR B 1 326 ? 53.82340  -19.76922 -61.00331 1.000 78.46328  ? 326 TYR B CD2 1 
ATOM   6390 C  CE1 . TYR B 1 326 ? 52.41759  -20.04253 -63.35759 1.000 65.13028  ? 326 TYR B CE1 1 
ATOM   6391 C  CE2 . TYR B 1 326 ? 52.70134  -20.56397 -61.04051 1.000 71.25573  ? 326 TYR B CE2 1 
ATOM   6392 C  CZ  . TYR B 1 326 ? 52.00278  -20.69739 -62.21849 1.000 59.81624  ? 326 TYR B CZ  1 
ATOM   6393 O  OH  . TYR B 1 326 ? 50.88245  -21.48936 -62.25841 1.000 73.58852  ? 326 TYR B OH  1 
ATOM   6394 N  N   . ASP B 1 327 ? 53.02243  -16.44194 -61.16091 1.000 69.84821  ? 327 ASP B N   1 
ATOM   6395 C  CA  . ASP B 1 327 ? 52.03407  -16.04437 -60.16908 1.000 72.03716  ? 327 ASP B CA  1 
ATOM   6396 C  C   . ASP B 1 327 ? 50.80424  -16.92867 -60.32542 1.000 72.17731  ? 327 ASP B C   1 
ATOM   6397 O  O   . ASP B 1 327 ? 50.50106  -17.40134 -61.42321 1.000 71.15903  ? 327 ASP B O   1 
ATOM   6398 C  CB  . ASP B 1 327 ? 51.66511  -14.56190 -60.32525 1.000 63.40056  ? 327 ASP B CB  1 
ATOM   6399 C  CG  . ASP B 1 327 ? 50.71047  -14.07005 -59.25298 1.000 71.66186  ? 327 ASP B CG  1 
ATOM   6400 O  OD1 . ASP B 1 327 ? 50.59597  -14.71695 -58.19192 1.000 70.76631  ? 327 ASP B OD1 1 
ATOM   6401 O  OD2 . ASP B 1 327 ? 50.07548  -13.02055 -59.47415 1.000 70.32462  ? 327 ASP B OD2 1 
ATOM   6402 N  N   . LEU B 1 328 ? 50.10283  -17.15353 -59.21858 1.000 61.58037  ? 328 LEU B N   1 
ATOM   6403 C  CA  . LEU B 1 328 ? 48.86035  -17.91301 -59.21000 1.000 60.66070  ? 328 LEU B CA  1 
ATOM   6404 C  C   . LEU B 1 328 ? 47.70273  -16.98588 -58.86288 1.000 60.78344  ? 328 LEU B C   1 
ATOM   6405 O  O   . LEU B 1 328 ? 47.73243  -16.30699 -57.83140 1.000 71.66390  ? 328 LEU B O   1 
ATOM   6406 C  CB  . LEU B 1 328 ? 48.94170  -19.07563 -58.21787 1.000 77.33254  ? 328 LEU B CB  1 
ATOM   6407 C  CG  . LEU B 1 328 ? 49.82100  -20.24119 -58.67911 1.000 73.40237  ? 328 LEU B CG  1 
ATOM   6408 C  CD1 . LEU B 1 328 ? 50.38575  -21.01029 -57.49561 1.000 71.68441  ? 328 LEU B CD1 1 
ATOM   6409 C  CD2 . LEU B 1 328 ? 49.03111  -21.17022 -59.58716 1.000 60.19322  ? 328 LEU B CD2 1 
ATOM   6410 N  N   . VAL B 1 329 ? 46.68309  -16.96927 -59.72075 1.000 63.97757  ? 329 VAL B N   1 
ATOM   6411 C  CA  . VAL B 1 329 ? 45.56646  -16.03703 -59.60544 1.000 65.16726  ? 329 VAL B CA  1 
ATOM   6412 C  C   . VAL B 1 329 ? 44.25978  -16.81051 -59.48622 1.000 64.35341  ? 329 VAL B C   1 
ATOM   6413 O  O   . VAL B 1 329 ? 44.25742  -18.04543 -59.42616 1.000 64.13261  ? 329 VAL B O   1 
ATOM   6414 C  CB  . VAL B 1 329 ? 45.52401  -15.06971 -60.80140 1.000 66.07617  ? 329 VAL B CB  1 
ATOM   6415 C  CG1 . VAL B 1 329 ? 46.85329  -14.35142 -60.94536 1.000 62.35087  ? 329 VAL B CG1 1 
ATOM   6416 C  CG2 . VAL B 1 329 ? 45.18146  -15.82243 -62.07372 1.000 68.71668  ? 329 VAL B CG2 1 
ATOM   6417 N  N   . GLY B 1 330 ? 43.14473  -16.09007 -59.45139 1.000 65.48422  ? 330 GLY B N   1 
ATOM   6418 C  CA  . GLY B 1 330 ? 41.85209  -16.67275 -59.16914 1.000 58.30923  ? 330 GLY B CA  1 
ATOM   6419 C  C   . GLY B 1 330 ? 41.45238  -16.46905 -57.71885 1.000 66.10301  ? 330 GLY B C   1 
ATOM   6420 O  O   . GLY B 1 330 ? 42.27471  -16.17918 -56.84918 1.000 71.74611  ? 330 GLY B O   1 
ATOM   6421 N  N   . GLN B 1 331 ? 40.15621  -16.62248 -57.45670 1.000 65.31598  ? 331 GLN B N   1 
ATOM   6422 C  CA  . GLN B 1 331 ? 39.62551  -16.34251 -56.12714 1.000 58.03119  ? 331 GLN B CA  1 
ATOM   6423 C  C   . GLN B 1 331 ? 40.34272  -17.18499 -55.08047 1.000 59.87095  ? 331 GLN B C   1 
ATOM   6424 O  O   . GLN B 1 331 ? 40.53243  -18.39102 -55.25907 1.000 74.17428  ? 331 GLN B O   1 
ATOM   6425 C  CB  . GLN B 1 331 ? 38.11986  -16.60831 -56.08361 1.000 60.71213  ? 331 GLN B CB  1 
ATOM   6426 C  CG  . GLN B 1 331 ? 37.42277  -15.96467 -54.89529 1.000 75.04315  ? 331 GLN B CG  1 
ATOM   6427 C  CD  . GLN B 1 331 ? 35.94625  -16.30226 -54.83105 1.000 74.96478  ? 331 GLN B CD  1 
ATOM   6428 O  OE1 . GLN B 1 331 ? 35.41220  -16.96828 -55.71776 1.000 72.81389  ? 331 GLN B OE1 1 
ATOM   6429 N  NE2 . GLN B 1 331 ? 35.27935  -15.84998 -53.77366 1.000 52.96489  ? 331 GLN B NE2 1 
ATOM   6430 N  N   . GLU B 1 332 ? 40.74766  -16.54044 -53.98601 1.000 63.10600  ? 332 GLU B N   1 
ATOM   6431 C  CA  . GLU B 1 332 ? 41.59156  -17.19005 -52.99093 1.000 66.91694  ? 332 GLU B CA  1 
ATOM   6432 C  C   . GLU B 1 332 ? 40.81273  -17.91446 -51.90275 1.000 68.78223  ? 332 GLU B C   1 
ATOM   6433 O  O   . GLU B 1 332 ? 41.32411  -18.89093 -51.34336 1.000 68.21564  ? 332 GLU B O   1 
ATOM   6434 C  CB  . GLU B 1 332 ? 42.52308  -16.16919 -52.33122 1.000 72.74308  ? 332 GLU B CB  1 
ATOM   6435 C  CG  . GLU B 1 332 ? 43.76732  -15.83815 -53.13480 1.000 84.52388  ? 332 GLU B CG  1 
ATOM   6436 C  CD  . GLU B 1 332 ? 44.85418  -15.21098 -52.28243 1.000 82.80557  ? 332 GLU B CD  1 
ATOM   6437 O  OE1 . GLU B 1 332 ? 45.20468  -15.79830 -51.23520 1.000 55.66471  ? 332 GLU B OE1 1 
ATOM   6438 O  OE2 . GLU B 1 332 ? 45.34683  -14.12473 -52.65421 1.000 77.50949  ? 332 GLU B OE2 1 
ATOM   6439 N  N   . ASP B 1 333 ? 39.59387  -17.46234 -51.57233 1.000 72.81285  ? 333 ASP B N   1 
ATOM   6440 C  CA  . ASP B 1 333 ? 38.87505  -18.08441 -50.45908 1.000 78.85082  ? 333 ASP B CA  1 
ATOM   6441 C  C   . ASP B 1 333 ? 38.44794  -19.51398 -50.77097 1.000 70.03934  ? 333 ASP B C   1 
ATOM   6442 O  O   . ASP B 1 333 ? 38.85312  -20.43380 -50.03785 1.000 68.59407  ? 333 ASP B O   1 
ATOM   6443 C  CB  . ASP B 1 333 ? 37.69452  -17.20671 -50.03410 1.000 76.35902  ? 333 ASP B CB  1 
ATOM   6444 C  CG  . ASP B 1 333 ? 38.10811  -16.07893 -49.11249 1.000 71.20707  ? 333 ASP B CG  1 
ATOM   6445 O  OD1 . ASP B 1 333 ? 39.32281  -15.90920 -48.88830 1.000 73.52799  ? 333 ASP B OD1 1 
ATOM   6446 O  OD2 . ASP B 1 333 ? 37.21658  -15.36617 -48.60663 1.000 70.59869  ? 333 ASP B OD2 1 
ATOM   6447 N  N   . PRO B 1 334 ? 37.65008  -19.78595 -51.81037 1.000 70.21902  ? 334 PRO B N   1 
ATOM   6448 C  CA  . PRO B 1 334 ? 37.15921  -21.15397 -52.00061 1.000 67.96295  ? 334 PRO B CA  1 
ATOM   6449 C  C   . PRO B 1 334 ? 38.13130  -22.07806 -52.71608 1.000 60.09062  ? 334 PRO B C   1 
ATOM   6450 O  O   . PRO B 1 334 ? 37.84823  -23.27560 -52.82691 1.000 53.90578  ? 334 PRO B O   1 
ATOM   6451 C  CB  . PRO B 1 334 ? 35.88791  -20.94143 -52.82114 1.000 64.38935  ? 334 PRO B CB  1 
ATOM   6452 C  CG  . PRO B 1 334 ? 36.23699  -19.79821 -53.69399 1.000 67.60745  ? 334 PRO B CG  1 
ATOM   6453 C  CD  . PRO B 1 334 ? 37.16500  -18.90661 -52.88765 1.000 75.98511  ? 334 PRO B CD  1 
ATOM   6454 N  N   . ASN B 1 335 ? 39.25408  -21.56759 -53.20398 1.000 59.24385  ? 335 ASN B N   1 
ATOM   6455 C  CA  . ASN B 1 335 ? 40.20339  -22.34909 -53.97737 1.000 62.78357  ? 335 ASN B CA  1 
ATOM   6456 C  C   . ASN B 1 335 ? 41.40362  -22.74596 -53.11359 1.000 62.19435  ? 335 ASN B C   1 
ATOM   6457 O  O   . ASN B 1 335 ? 41.40405  -22.58281 -51.88915 1.000 70.83218  ? 335 ASN B O   1 
ATOM   6458 C  CB  . ASN B 1 335 ? 40.61335  -21.56967 -55.22750 1.000 65.34688  ? 335 ASN B CB  1 
ATOM   6459 C  CG  . ASN B 1 335 ? 39.45033  -21.35044 -56.18146 1.000 62.47583  ? 335 ASN B CG  1 
ATOM   6460 O  OD1 . ASN B 1 335 ? 38.39784  -21.97839 -56.05043 1.000 54.59133  ? 335 ASN B OD1 1 
ATOM   6461 N  ND2 . ASN B 1 335 ? 39.63944  -20.46722 -57.15421 1.000 75.52587  ? 335 ASN B ND2 1 
ATOM   6462 N  N   . PHE B 1 336 ? 42.43412  -23.29032 -53.75940 1.000 57.19887  ? 336 PHE B N   1 
ATOM   6463 C  CA  . PHE B 1 336 ? 43.56905  -23.88732 -53.07402 1.000 52.87353  ? 336 PHE B CA  1 
ATOM   6464 C  C   . PHE B 1 336 ? 44.48500  -22.82211 -52.47817 1.000 58.74559  ? 336 PHE B C   1 
ATOM   6465 O  O   . PHE B 1 336 ? 44.26509  -21.61556 -52.61082 1.000 78.79159  ? 336 PHE B O   1 
ATOM   6466 C  CB  . PHE B 1 336 ? 44.35118  -24.78513 -54.03028 1.000 62.17309  ? 336 PHE B CB  1 
ATOM   6467 C  CG  . PHE B 1 336 ? 43.67108  -26.08628 -54.32998 1.000 76.63006  ? 336 PHE B CG  1 
ATOM   6468 C  CD1 . PHE B 1 336 ? 43.61545  -27.08660 -53.37384 1.000 69.15326  ? 336 PHE B CD1 1 
ATOM   6469 C  CD2 . PHE B 1 336 ? 43.08289  -26.31188 -55.56283 1.000 74.83826  ? 336 PHE B CD2 1 
ATOM   6470 C  CE1 . PHE B 1 336 ? 42.99002  -28.28652 -53.64249 1.000 61.70437  ? 336 PHE B CE1 1 
ATOM   6471 C  CE2 . PHE B 1 336 ? 42.45430  -27.50988 -55.83807 1.000 72.14058  ? 336 PHE B CE2 1 
ATOM   6472 C  CZ  . PHE B 1 336 ? 42.40789  -28.49883 -54.87572 1.000 68.14195  ? 336 PHE B CZ  1 
ATOM   6473 N  N   . SER B 1 337 ? 45.53403  -23.29242 -51.81358 1.000 55.10178  ? 337 SER B N   1 
ATOM   6474 C  CA  . SER B 1 337 ? 46.53470  -22.46705 -51.15787 1.000 62.58769  ? 337 SER B CA  1 
ATOM   6475 C  C   . SER B 1 337 ? 47.83727  -22.51623 -51.94835 1.000 56.99915  ? 337 SER B C   1 
ATOM   6476 O  O   . SER B 1 337 ? 47.96806  -23.24373 -52.93682 1.000 72.63161  ? 337 SER B O   1 
ATOM   6477 C  CB  . SER B 1 337 ? 46.75342  -22.94052 -49.72035 1.000 69.03155  ? 337 SER B CB  1 
ATOM   6478 O  OG  . SER B 1 337 ? 47.18306  -24.29243 -49.69704 1.000 68.66377  ? 337 SER B OG  1 
ATOM   6479 N  N   . LEU B 1 338 ? 48.81318  -21.72689 -51.50025 1.000 60.79474  ? 338 LEU B N   1 
ATOM   6480 C  CA  . LEU B 1 338 ? 50.14179  -21.78278 -52.09286 1.000 61.87196  ? 338 LEU B CA  1 
ATOM   6481 C  C   . LEU B 1 338 ? 50.96103  -22.95504 -51.57114 1.000 68.35924  ? 338 LEU B C   1 
ATOM   6482 O  O   . LEU B 1 338 ? 51.98327  -23.29714 -52.17534 1.000 80.21068  ? 338 LEU B O   1 
ATOM   6483 C  CB  . LEU B 1 338 ? 50.89139  -20.47280 -51.83797 1.000 63.58533  ? 338 LEU B CB  1 
ATOM   6484 C  CG  . LEU B 1 338 ? 50.34216  -19.22496 -52.53267 1.000 64.40554  ? 338 LEU B CG  1 
ATOM   6485 C  CD1 . LEU B 1 338 ? 51.19621  -18.01234 -52.20954 1.000 68.60901  ? 338 LEU B CD1 1 
ATOM   6486 C  CD2 . LEU B 1 338 ? 50.28248  -19.44911 -54.03175 1.000 71.47557  ? 338 LEU B CD2 1 
ATOM   6487 N  N   . LEU B 1 339 ? 50.53775  -23.57429 -50.46652 1.000 64.27450  ? 339 LEU B N   1 
ATOM   6488 C  CA  . LEU B 1 339 ? 51.24255  -24.73720 -49.93954 1.000 66.60567  ? 339 LEU B CA  1 
ATOM   6489 C  C   . LEU B 1 339 ? 50.83311  -26.01930 -50.65175 1.000 70.56985  ? 339 LEU B C   1 
ATOM   6490 O  O   . LEU B 1 339 ? 51.64300  -26.94562 -50.76793 1.000 69.26282  ? 339 LEU B O   1 
ATOM   6491 C  CB  . LEU B 1 339 ? 50.99386  -24.86334 -48.43650 1.000 71.63957  ? 339 LEU B CB  1 
ATOM   6492 C  CG  . LEU B 1 339 ? 51.84795  -25.87847 -47.67739 1.000 64.60592  ? 339 LEU B CG  1 
ATOM   6493 C  CD1 . LEU B 1 339 ? 53.29751  -25.42900 -47.63748 1.000 71.13532  ? 339 LEU B CD1 1 
ATOM   6494 C  CD2 . LEU B 1 339 ? 51.30944  -26.08050 -46.27261 1.000 59.20537  ? 339 LEU B CD2 1 
ATOM   6495 N  N   . HIS B 1 340 ? 49.59122  -26.08702 -51.13648 1.000 69.25832  ? 340 HIS B N   1 
ATOM   6496 C  CA  . HIS B 1 340 ? 49.13851  -27.20733 -51.95385 1.000 64.27292  ? 340 HIS B CA  1 
ATOM   6497 C  C   . HIS B 1 340 ? 49.93811  -27.34272 -53.24593 1.000 65.84520  ? 340 HIS B C   1 
ATOM   6498 O  O   . HIS B 1 340 ? 49.81997  -28.36714 -53.92687 1.000 69.75583  ? 340 HIS B O   1 
ATOM   6499 C  CB  . HIS B 1 340 ? 47.64228  -27.03577 -52.24889 1.000 57.66629  ? 340 HIS B CB  1 
ATOM   6500 C  CG  . HIS B 1 340 ? 47.03730  -28.14872 -53.04689 1.000 57.81847  ? 340 HIS B CG  1 
ATOM   6501 N  ND1 . HIS B 1 340 ? 46.79623  -28.04502 -54.39902 1.000 66.50304  ? 340 HIS B ND1 1 
ATOM   6502 C  CD2 . HIS B 1 340 ? 46.60892  -29.38013 -52.68216 1.000 75.16857  ? 340 HIS B CD2 1 
ATOM   6503 C  CE1 . HIS B 1 340 ? 46.25135  -29.16655 -54.83477 1.000 74.47312  ? 340 HIS B CE1 1 
ATOM   6504 N  NE2 . HIS B 1 340 ? 46.12753  -29.99388 -53.81296 1.000 86.29784  ? 340 HIS B NE2 1 
ATOM   6505 N  N   . TYR B 1 341 ? 50.75906  -26.34584 -53.58725 1.000 70.28298  ? 341 TYR B N   1 
ATOM   6506 C  CA  . TYR B 1 341 ? 51.57731  -26.35652 -54.79468 1.000 64.83375  ? 341 TYR B CA  1 
ATOM   6507 C  C   . TYR B 1 341 ? 53.06725  -26.25650 -54.48292 1.000 69.73336  ? 341 TYR B C   1 
ATOM   6508 O  O   . TYR B 1 341 ? 53.83821  -25.78973 -55.32752 1.000 72.31140  ? 341 TYR B O   1 
ATOM   6509 C  CB  . TYR B 1 341 ? 51.17601  -25.20734 -55.72108 1.000 61.79373  ? 341 TYR B CB  1 
ATOM   6510 C  CG  . TYR B 1 341 ? 49.76412  -25.26792 -56.25293 1.000 65.67638  ? 341 TYR B CG  1 
ATOM   6511 C  CD1 . TYR B 1 341 ? 49.28869  -26.39699 -56.90855 1.000 71.16960  ? 341 TYR B CD1 1 
ATOM   6512 C  CD2 . TYR B 1 341 ? 48.90884  -24.18533 -56.10583 1.000 64.55517  ? 341 TYR B CD2 1 
ATOM   6513 C  CE1 . TYR B 1 341 ? 47.99603  -26.44257 -57.40005 1.000 73.21335  ? 341 TYR B CE1 1 
ATOM   6514 C  CE2 . TYR B 1 341 ? 47.62207  -24.22168 -56.59027 1.000 74.28372  ? 341 TYR B CE2 1 
ATOM   6515 C  CZ  . TYR B 1 341 ? 47.16893  -25.34865 -57.23614 1.000 73.30677  ? 341 TYR B CZ  1 
ATOM   6516 O  OH  . TYR B 1 341 ? 45.88055  -25.36979 -57.71328 1.000 69.20663  ? 341 TYR B OH  1 
ATOM   6517 N  N   . LEU B 1 342 ? 53.49046  -26.67059 -53.28493 1.000 67.94896  ? 342 LEU B N   1 
ATOM   6518 C  CA  . LEU B 1 342 ? 54.87534  -26.44519 -52.87619 1.000 68.63793  ? 342 LEU B CA  1 
ATOM   6519 C  C   . LEU B 1 342 ? 55.85672  -27.22902 -53.73920 1.000 78.80770  ? 342 LEU B C   1 
ATOM   6520 O  O   . LEU B 1 342 ? 56.92698  -26.71593 -54.08522 1.000 68.53230  ? 342 LEU B O   1 
ATOM   6521 C  CB  . LEU B 1 342 ? 55.06451  -26.80337 -51.40297 1.000 50.27108  ? 342 LEU B CB  1 
ATOM   6522 C  CG  . LEU B 1 342 ? 56.50267  -26.62680 -50.90439 1.000 56.19825  ? 342 LEU B CG  1 
ATOM   6523 C  CD1 . LEU B 1 342 ? 56.96137  -25.17970 -51.04095 1.000 67.86737  ? 342 LEU B CD1 1 
ATOM   6524 C  CD2 . LEU B 1 342 ? 56.64720  -27.10682 -49.47142 1.000 77.52418  ? 342 LEU B CD2 1 
ATOM   6525 N  N   . ASP B 1 343 ? 55.51992  -28.47482 -54.08603 1.000 82.59086  ? 343 ASP B N   1 
ATOM   6526 C  CA  . ASP B 1 343 ? 56.42849  -29.28997 -54.88681 1.000 80.86802  ? 343 ASP B CA  1 
ATOM   6527 C  C   . ASP B 1 343 ? 56.79222  -28.60434 -56.19677 1.000 76.40361  ? 343 ASP B C   1 
ATOM   6528 O  O   . ASP B 1 343 ? 57.92184  -28.74615 -56.68008 1.000 77.57582  ? 343 ASP B O   1 
ATOM   6529 C  CB  . ASP B 1 343 ? 55.80717  -30.65912 -55.16195 1.000 79.43054  ? 343 ASP B CB  1 
ATOM   6530 C  CG  . ASP B 1 343 ? 55.46887  -31.41182 -53.89227 1.000 89.25340  ? 343 ASP B CG  1 
ATOM   6531 O  OD1 . ASP B 1 343 ? 56.24326  -31.31500 -52.91618 1.000 86.60777  ? 343 ASP B OD1 1 
ATOM   6532 O  OD2 . ASP B 1 343 ? 54.42658  -32.09924 -53.87257 1.000 96.33953  ? 343 ASP B OD2 1 
ATOM   6533 N  N   . ALA B 1 344 ? 55.85536  -27.85980 -56.78317 1.000 72.05035  ? 344 ALA B N   1 
ATOM   6534 C  CA  . ALA B 1 344 ? 56.13705  -27.14505 -58.02189 1.000 70.95738  ? 344 ALA B CA  1 
ATOM   6535 C  C   . ALA B 1 344 ? 56.97770  -25.89839 -57.77307 1.000 72.70073  ? 344 ALA B C   1 
ATOM   6536 O  O   . ALA B 1 344 ? 57.97367  -25.66465 -58.46614 1.000 80.23053  ? 344 ALA B O   1 
ATOM   6537 C  CB  . ALA B 1 344 ? 54.82633  -26.77552 -58.71967 1.000 72.35339  ? 344 ALA B CB  1 
ATOM   6538 N  N   . LEU B 1 345 ? 56.59681  -25.09269 -56.77960 1.000 77.26688  ? 345 LEU B N   1 
ATOM   6539 C  CA  . LEU B 1 345 ? 57.22260  -23.79162 -56.57965 1.000 77.89572  ? 345 LEU B CA  1 
ATOM   6540 C  C   . LEU B 1 345 ? 58.60970  -23.87885 -55.95212 1.000 81.89024  ? 345 LEU B C   1 
ATOM   6541 O  O   . LEU B 1 345 ? 59.32582  -22.87175 -55.95057 1.000 79.47393  ? 345 LEU B O   1 
ATOM   6542 C  CB  . LEU B 1 345 ? 56.30817  -22.90822 -55.72634 1.000 76.67360  ? 345 LEU B CB  1 
ATOM   6543 C  CG  . LEU B 1 345 ? 54.90392  -22.69617 -56.30242 1.000 75.48220  ? 345 LEU B CG  1 
ATOM   6544 C  CD1 . LEU B 1 345 ? 53.99789  -21.99627 -55.29872 1.000 62.80790  ? 345 LEU B CD1 1 
ATOM   6545 C  CD2 . LEU B 1 345 ? 54.96004  -21.92138 -57.61535 1.000 75.38902  ? 345 LEU B CD2 1 
ATOM   6546 N  N   . LEU B 1 346 ? 59.00898  -25.03982 -55.42406 1.000 77.89804  ? 346 LEU B N   1 
ATOM   6547 C  CA  . LEU B 1 346 ? 60.38043  -25.24060 -54.96736 1.000 73.07599  ? 346 LEU B CA  1 
ATOM   6548 C  C   . LEU B 1 346 ? 61.26909  -25.84699 -56.04218 1.000 79.39045  ? 346 LEU B C   1 
ATOM   6549 O  O   . LEU B 1 346 ? 62.49453  -25.78381 -55.90994 1.000 76.47355  ? 346 LEU B O   1 
ATOM   6550 C  CB  . LEU B 1 346 ? 60.42435  -26.13844 -53.71532 1.000 80.19154  ? 346 LEU B CB  1 
ATOM   6551 C  CG  . LEU B 1 346 ? 61.54415  -26.02851 -52.65648 1.000 90.08783  ? 346 LEU B CG  1 
ATOM   6552 C  CD1 . LEU B 1 346 ? 61.01832  -26.49014 -51.29992 1.000 77.96380  ? 346 LEU B CD1 1 
ATOM   6553 C  CD2 . LEU B 1 346 ? 62.79719  -26.82587 -53.00973 1.000 109.37086 ? 346 LEU B CD2 1 
ATOM   6554 N  N   . TYR B 1 347 ? 60.68625  -26.39632 -57.10954 1.000 86.09670  ? 347 TYR B N   1 
ATOM   6555 C  CA  . TYR B 1 347 ? 61.47599  -27.01549 -58.17278 1.000 81.82516  ? 347 TYR B CA  1 
ATOM   6556 C  C   . TYR B 1 347 ? 62.62305  -26.13875 -58.66742 1.000 79.90245  ? 347 TYR B C   1 
ATOM   6557 O  O   . TYR B 1 347 ? 63.72137  -26.68119 -58.87470 1.000 80.33538  ? 347 TYR B O   1 
ATOM   6558 C  CB  . TYR B 1 347 ? 60.55646  -27.41705 -59.33796 1.000 79.98760  ? 347 TYR B CB  1 
ATOM   6559 C  CG  . TYR B 1 347 ? 61.27040  -28.07431 -60.50125 1.000 90.15024  ? 347 TYR B CG  1 
ATOM   6560 C  CD1 . TYR B 1 347 ? 61.76981  -27.31859 -61.55181 1.000 93.36578  ? 347 TYR B CD1 1 
ATOM   6561 C  CD2 . TYR B 1 347 ? 61.43705  -29.45338 -60.54992 1.000 76.35344  ? 347 TYR B CD2 1 
ATOM   6562 C  CE1 . TYR B 1 347 ? 62.41949  -27.90888 -62.61307 1.000 87.86470  ? 347 TYR B CE1 1 
ATOM   6563 C  CE2 . TYR B 1 347 ? 62.08550  -30.05520 -61.61033 1.000 78.70322  ? 347 TYR B CE2 1 
ATOM   6564 C  CZ  . TYR B 1 347 ? 62.57444  -29.27763 -62.63902 1.000 86.59508  ? 347 TYR B CZ  1 
ATOM   6565 O  OH  . TYR B 1 347 ? 63.22131  -29.86785 -63.69981 1.000 102.04310 ? 347 TYR B OH  1 
ATOM   6566 N  N   . PRO B 1 348 ? 62.46668  -24.82264 -58.86940 1.000 76.11518  ? 348 PRO B N   1 
ATOM   6567 C  CA  . PRO B 1 348 ? 63.63195  -24.02054 -59.28505 1.000 83.69991  ? 348 PRO B CA  1 
ATOM   6568 C  C   . PRO B 1 348 ? 64.80590  -24.08944 -58.31781 1.000 81.58109  ? 348 PRO B C   1 
ATOM   6569 O  O   . PRO B 1 348 ? 65.95858  -23.96078 -58.75136 1.000 88.83796  ? 348 PRO B O   1 
ATOM   6570 C  CB  . PRO B 1 348 ? 63.06388  -22.59839 -59.37616 1.000 83.63938  ? 348 PRO B CB  1 
ATOM   6571 C  CG  . PRO B 1 348 ? 61.62203  -22.78748 -59.63828 1.000 81.34074  ? 348 PRO B CG  1 
ATOM   6572 C  CD  . PRO B 1 348 ? 61.23198  -24.01526 -58.87380 1.000 68.11431  ? 348 PRO B CD  1 
ATOM   6573 N  N   . SER B 1 349 ? 64.55349  -24.29820 -57.02509 1.000 88.01832  ? 349 SER B N   1 
ATOM   6574 C  CA  . SER B 1 349 ? 65.60851  -24.30088 -56.01699 1.000 88.59621  ? 349 SER B CA  1 
ATOM   6575 C  C   . SER B 1 349 ? 66.25304  -25.67080 -55.83970 1.000 100.45647 ? 349 SER B C   1 
ATOM   6576 O  O   . SER B 1 349 ? 67.47339  -25.75705 -55.66264 1.000 102.44409 ? 349 SER B O   1 
ATOM   6577 C  CB  . SER B 1 349 ? 65.05359  -23.82056 -54.67468 1.000 96.22085  ? 349 SER B CB  1 
ATOM   6578 O  OG  . SER B 1 349 ? 64.32027  -22.61798 -54.83070 1.000 121.07221 ? 349 SER B OG  1 
ATOM   6579 N  N   . ILE B 1 350 ? 65.46672  -26.74721 -55.88565 1.000 98.49981  ? 350 ILE B N   1 
ATOM   6580 C  CA  . ILE B 1 350 ? 66.03715  -28.08592 -55.79104 1.000 88.86876  ? 350 ILE B CA  1 
ATOM   6581 C  C   . ILE B 1 350 ? 66.58719  -28.42137 -57.17171 1.000 99.28029  ? 350 ILE B C   1 
ATOM   6582 O  O   . ILE B 1 350 ? 65.92256  -29.06497 -57.99286 1.000 107.57739 ? 350 ILE B O   1 
ATOM   6583 C  CB  . ILE B 1 350 ? 65.00043  -29.11669 -55.28676 1.000 85.52972  ? 350 ILE B CB  1 
ATOM   6584 C  CG1 . ILE B 1 350 ? 65.54044  -30.55291 -55.35742 1.000 106.93220 ? 350 ILE B CG1 1 
ATOM   6585 C  CG2 . ILE B 1 350 ? 63.64515  -28.96059 -55.99270 1.000 79.50078  ? 350 ILE B CG2 1 
ATOM   6586 C  CD1 . ILE B 1 350 ? 66.54297  -30.88461 -54.27439 1.000 97.42814  ? 350 ILE B CD1 1 
ATOM   6587 N  N   . GLN B 1 351 ? 67.81253  -27.97552 -57.43380 1.000 92.23043  ? 351 GLN B N   1 
ATOM   6588 C  CA  . GLN B 1 351 ? 68.43936  -28.13172 -58.73802 1.000 99.14277  ? 351 GLN B CA  1 
ATOM   6589 C  C   . GLN B 1 351 ? 69.93531  -27.89964 -58.59125 1.000 110.25548 ? 351 GLN B C   1 
ATOM   6590 O  O   . GLN B 1 351 ? 70.37585  -27.18786 -57.68447 1.000 104.07778 ? 351 GLN B O   1 
ATOM   6591 C  CB  . GLN B 1 351 ? 67.84117  -27.16707 -59.77026 1.000 93.56759  ? 351 GLN B CB  1 
ATOM   6592 C  CG  . GLN B 1 351 ? 67.53731  -27.80573 -61.12662 1.000 105.26902 ? 351 GLN B CG  1 
ATOM   6593 C  CD  . GLN B 1 351 ? 66.26226  -28.63918 -61.12693 1.000 95.00432  ? 351 GLN B CD  1 
ATOM   6594 O  OE1 . GLN B 1 351 ? 65.22239  -28.20309 -60.63578 1.000 90.95305  ? 351 GLN B OE1 1 
ATOM   6595 N  NE2 . GLN B 1 351 ? 66.33889  -29.84234 -61.68742 1.000 95.78106  ? 351 GLN B NE2 1 
ATOM   6596 N  N   . ASN B 1 352 ? 70.70812  -28.51167 -59.48164 1.000 121.01032 ? 352 ASN B N   1 
ATOM   6597 C  CA  . ASN B 1 352 ? 72.16486  -28.37544 -59.47648 1.000 125.63305 ? 352 ASN B CA  1 
ATOM   6598 C  C   . ASN B 1 352 ? 72.64897  -27.90410 -60.84080 1.000 120.93162 ? 352 ASN B C   1 
ATOM   6599 O  O   . ASN B 1 352 ? 72.55489  -28.66643 -61.82574 1.000 111.58910 ? 352 ASN B O   1 
ATOM   6600 C  CB  . ASN B 1 352 ? 72.84764  -29.68569 -59.09507 1.000 121.88260 ? 352 ASN B CB  1 
ATOM   6601 C  CG  . ASN B 1 352 ? 74.35358  -29.53868 -58.97346 1.000 131.54125 ? 352 ASN B CG  1 
ATOM   6602 O  OD1 . ASN B 1 352 ? 74.84649  -28.75208 -58.16306 1.000 130.32818 ? 352 ASN B OD1 1 
ATOM   6603 N  ND2 . ASN B 1 352 ? 75.09176  -30.29388 -59.77784 1.000 126.61182 ? 352 ASN B ND2 1 
ATOM   6604 N  N   . PRO B 1 353 ? 73.15702  -26.67070 -60.95475 1.000 122.72273 ? 353 PRO B N   1 
ATOM   6605 C  CA  . PRO B 1 353 ? 73.17208  -25.63124 -59.91353 1.000 113.32487 ? 353 PRO B CA  1 
ATOM   6606 C  C   . PRO B 1 353 ? 71.76865  -25.07965 -59.68195 1.000 116.36369 ? 353 PRO B C   1 
ATOM   6607 O  O   . PRO B 1 353 ? 70.92508  -25.15034 -60.57344 1.000 118.19278 ? 353 PRO B O   1 
ATOM   6608 C  CB  . PRO B 1 353 ? 74.13013  -24.57316 -60.48773 1.000 107.27942 ? 353 PRO B CB  1 
ATOM   6609 C  CG  . PRO B 1 353 ? 74.97773  -25.31429 -61.48726 1.000 117.63198 ? 353 PRO B CG  1 
ATOM   6610 C  CD  . PRO B 1 353 ? 74.03780  -26.32214 -62.08229 1.000 120.48677 ? 353 PRO B CD  1 
ATOM   6611 N  N   . PRO B 1 354 ? 71.48430  -24.54934 -58.49247 1.000 117.24751 ? 354 PRO B N   1 
ATOM   6612 C  CA  . PRO B 1 354 ? 70.14682  -24.00640 -58.23310 1.000 109.26203 ? 354 PRO B CA  1 
ATOM   6613 C  C   . PRO B 1 354 ? 69.83770  -22.82494 -59.13835 1.000 91.55050  ? 354 PRO B C   1 
ATOM   6614 O  O   . PRO B 1 354 ? 70.71841  -22.04810 -59.51292 1.000 91.23879  ? 354 PRO B O   1 
ATOM   6615 C  CB  . PRO B 1 354 ? 70.21316  -23.57998 -56.76109 1.000 90.10183  ? 354 PRO B CB  1 
ATOM   6616 C  CG  . PRO B 1 354 ? 71.33192  -24.38076 -56.18203 1.000 106.73746 ? 354 PRO B CG  1 
ATOM   6617 C  CD  . PRO B 1 354 ? 72.33232  -24.52300 -57.28943 1.000 111.02485 ? 354 PRO B CD  1 
ATOM   6618 N  N   . TYR B 1 355 ? 68.56539  -22.70716 -59.49722 1.000 80.11347  ? 355 TYR B N   1 
ATOM   6619 C  CA  . TYR B 1 355 ? 68.05571  -21.59556 -60.28231 1.000 88.38986  ? 355 TYR B CA  1 
ATOM   6620 C  C   . TYR B 1 355 ? 67.07295  -20.79801 -59.43536 1.000 91.02031  ? 355 TYR B C   1 
ATOM   6621 O  O   . TYR B 1 355 ? 66.51842  -21.29913 -58.45327 1.000 95.20526  ? 355 TYR B O   1 
ATOM   6622 C  CB  . TYR B 1 355 ? 67.38552  -22.09870 -61.56844 1.000 87.01032  ? 355 TYR B CB  1 
ATOM   6623 C  CG  . TYR B 1 355 ? 67.08387  -21.01833 -62.58403 1.000 96.40235  ? 355 TYR B CG  1 
ATOM   6624 C  CD1 . TYR B 1 355 ? 68.06601  -20.11841 -62.97999 1.000 110.64736 ? 355 TYR B CD1 1 
ATOM   6625 C  CD2 . TYR B 1 355 ? 65.82623  -20.91044 -63.16421 1.000 85.34911  ? 355 TYR B CD2 1 
ATOM   6626 C  CE1 . TYR B 1 355 ? 67.80065  -19.13077 -63.90932 1.000 90.82990  ? 355 TYR B CE1 1 
ATOM   6627 C  CE2 . TYR B 1 355 ? 65.55169  -19.92657 -64.09777 1.000 91.60543  ? 355 TYR B CE2 1 
ATOM   6628 C  CZ  . TYR B 1 355 ? 66.54406  -19.03995 -64.46533 1.000 86.71944  ? 355 TYR B CZ  1 
ATOM   6629 O  OH  . TYR B 1 355 ? 66.28125  -18.05756 -65.39133 1.000 98.66143  ? 355 TYR B OH  1 
ATOM   6630 N  N   . ARG B 1 356 ? 66.87177  -19.53792 -59.80860 1.000 86.81430  ? 356 ARG B N   1 
ATOM   6631 C  CA  . ARG B 1 356 ? 65.95035  -18.65727 -59.09609 1.000 82.17780  ? 356 ARG B CA  1 
ATOM   6632 C  C   . ARG B 1 356 ? 64.87923  -18.17925 -60.06540 1.000 79.66868  ? 356 ARG B C   1 
ATOM   6633 O  O   . ARG B 1 356 ? 65.14404  -17.32877 -60.92308 1.000 82.78416  ? 356 ARG B O   1 
ATOM   6634 C  CB  . ARG B 1 356 ? 66.68060  -17.47088 -58.46834 1.000 73.72664  ? 356 ARG B CB  1 
ATOM   6635 C  CG  . ARG B 1 356 ? 66.27840  -17.22990 -57.02130 1.000 79.52400  ? 356 ARG B CG  1 
ATOM   6636 C  CD  . ARG B 1 356 ? 66.57680  -15.81244 -56.56242 1.000 102.22479 ? 356 ARG B CD  1 
ATOM   6637 N  NE  . ARG B 1 356 ? 65.56269  -14.86483 -57.00841 1.000 111.49537 ? 356 ARG B NE  1 
ATOM   6638 C  CZ  . ARG B 1 356 ? 65.45249  -13.62056 -56.56281 1.000 109.70273 ? 356 ARG B CZ  1 
ATOM   6639 N  NH1 . ARG B 1 356 ? 66.27977  -13.13664 -55.65075 1.000 99.34767  ? 356 ARG B NH1 1 
ATOM   6640 N  NH2 . ARG B 1 356 ? 64.48449  -12.84287 -57.04084 1.000 91.03842  ? 356 ARG B NH2 1 
ATOM   6641 N  N   . LEU B 1 357 ? 63.67420  -18.72688 -59.93167 1.000 77.19970  ? 357 LEU B N   1 
ATOM   6642 C  CA  . LEU B 1 357 ? 62.52424  -18.21170 -60.65738 1.000 70.90428  ? 357 LEU B CA  1 
ATOM   6643 C  C   . LEU B 1 357 ? 61.83815  -17.17241 -59.78135 1.000 71.99623  ? 357 LEU B C   1 
ATOM   6644 O  O   . LEU B 1 357 ? 61.28608  -17.53429 -58.72910 1.000 83.54999  ? 357 LEU B O   1 
ATOM   6645 C  CB  . LEU B 1 357 ? 61.55737  -19.33525 -61.01018 1.000 70.80913  ? 357 LEU B CB  1 
ATOM   6646 C  CG  . LEU B 1 357 ? 60.30438  -18.91762 -61.78096 1.000 59.07505  ? 357 LEU B CG  1 
ATOM   6647 C  CD1 . LEU B 1 357 ? 60.67228  -18.42311 -63.17122 1.000 61.95810  ? 357 LEU B CD1 1 
ATOM   6648 C  CD2 . LEU B 1 357 ? 59.29609  -20.05582 -61.85840 1.000 54.46993  ? 357 LEU B CD2 1 
ATOM   6649 N  N   . PRO B 1 358 ? 61.85238  -15.89168 -60.15055 1.000 71.03193  ? 358 PRO B N   1 
ATOM   6650 C  CA  . PRO B 1 358 ? 61.18599  -14.87936 -59.32350 1.000 75.79953  ? 358 PRO B CA  1 
ATOM   6651 C  C   . PRO B 1 358 ? 59.68424  -15.11562 -59.26257 1.000 79.48319  ? 358 PRO B C   1 
ATOM   6652 O  O   . PRO B 1 358 ? 59.08072  -15.66123 -60.18814 1.000 71.00354  ? 358 PRO B O   1 
ATOM   6653 C  CB  . PRO B 1 358 ? 61.52036  -13.56296 -60.03653 1.000 81.54680  ? 358 PRO B CB  1 
ATOM   6654 C  CG  . PRO B 1 358 ? 62.75979  -13.86778 -60.82413 1.000 72.61799  ? 358 PRO B CG  1 
ATOM   6655 C  CD  . PRO B 1 358 ? 62.58947  -15.28701 -61.27161 1.000 78.05133  ? 358 PRO B CD  1 
ATOM   6656 N  N   . TYR B 1 359 ? 59.08221  -14.70530 -58.14749 1.000 81.16665  ? 359 TYR B N   1 
ATOM   6657 C  CA  . TYR B 1 359 ? 57.66954  -14.94427 -57.89238 1.000 79.52458  ? 359 TYR B CA  1 
ATOM   6658 C  C   . TYR B 1 359 ? 56.96247  -13.64178 -57.54565 1.000 74.94499  ? 359 TYR B C   1 
ATOM   6659 O  O   . TYR B 1 359 ? 57.56005  -12.71736 -56.98932 1.000 71.12797  ? 359 TYR B O   1 
ATOM   6660 C  CB  . TYR B 1 359 ? 57.47308  -15.96602 -56.76715 1.000 76.62114  ? 359 TYR B CB  1 
ATOM   6661 C  CG  . TYR B 1 359 ? 57.80132  -17.38679 -57.16997 1.000 74.11253  ? 359 TYR B CG  1 
ATOM   6662 C  CD1 . TYR B 1 359 ? 57.07835  -18.02792 -58.16769 1.000 81.11634  ? 359 TYR B CD1 1 
ATOM   6663 C  CD2 . TYR B 1 359 ? 58.82488  -18.09016 -56.54831 1.000 72.73694  ? 359 TYR B CD2 1 
ATOM   6664 C  CE1 . TYR B 1 359 ? 57.36829  -19.32702 -58.53968 1.000 78.72243  ? 359 TYR B CE1 1 
ATOM   6665 C  CE2 . TYR B 1 359 ? 59.12208  -19.39204 -56.91368 1.000 81.03213  ? 359 TYR B CE2 1 
ATOM   6666 C  CZ  . TYR B 1 359 ? 58.39011  -20.00437 -57.90992 1.000 76.35551  ? 359 TYR B CZ  1 
ATOM   6667 O  OH  . TYR B 1 359 ? 58.67916  -21.29794 -58.27914 1.000 89.44055  ? 359 TYR B OH  1 
ATOM   6668 N  N   . PHE B 1 360 ? 55.67868  -13.57919 -57.89285 1.000 79.54618  ? 360 PHE B N   1 
ATOM   6669 C  CA  . PHE B 1 360 ? 54.86348  -12.37296 -57.74002 1.000 71.98563  ? 360 PHE B CA  1 
ATOM   6670 C  C   . PHE B 1 360 ? 53.49599  -12.73194 -57.15915 1.000 65.94328  ? 360 PHE B C   1 
ATOM   6671 O  O   . PHE B 1 360 ? 52.45296  -12.32356 -57.66996 1.000 70.52394  ? 360 PHE B O   1 
ATOM   6672 C  CB  . PHE B 1 360 ? 54.71653  -11.65157 -59.07995 1.000 71.10216  ? 360 PHE B CB  1 
ATOM   6673 C  CG  . PHE B 1 360 ? 56.02069  -11.18704 -59.67141 1.000 66.97019  ? 360 PHE B CG  1 
ATOM   6674 C  CD1 . PHE B 1 360 ? 56.79779  -12.04184 -60.43882 1.000 62.71413  ? 360 PHE B CD1 1 
ATOM   6675 C  CD2 . PHE B 1 360 ? 56.45912  -9.88766  -59.47624 1.000 75.04837  ? 360 PHE B CD2 1 
ATOM   6676 C  CE1 . PHE B 1 360 ? 57.99225  -11.61262 -60.98682 1.000 70.06997  ? 360 PHE B CE1 1 
ATOM   6677 C  CE2 . PHE B 1 360 ? 57.65066  -9.45111  -60.02405 1.000 76.09100  ? 360 PHE B CE2 1 
ATOM   6678 C  CZ  . PHE B 1 360 ? 58.41878  -10.31509 -60.78040 1.000 82.27270  ? 360 PHE B CZ  1 
ATOM   6679 N  N   . PHE B 1 361 ? 53.49435  -13.49550 -56.06701 1.000 65.11854  ? 361 PHE B N   1 
ATOM   6680 C  CA  . PHE B 1 361 ? 52.28639  -14.17372 -55.60471 1.000 69.23503  ? 361 PHE B CA  1 
ATOM   6681 C  C   . PHE B 1 361 ? 51.19603  -13.21288 -55.13856 1.000 72.16149  ? 361 PHE B C   1 
ATOM   6682 O  O   . PHE B 1 361 ? 51.46577  -12.21564 -54.46380 1.000 69.23370  ? 361 PHE B O   1 
ATOM   6683 C  CB  . PHE B 1 361 ? 52.62258  -15.12158 -54.45447 1.000 72.94665  ? 361 PHE B CB  1 
ATOM   6684 C  CG  . PHE B 1 361 ? 53.41987  -16.32204 -54.86418 1.000 82.31901  ? 361 PHE B CG  1 
ATOM   6685 C  CD1 . PHE B 1 361 ? 52.92983  -17.20723 -55.80915 1.000 77.68695  ? 361 PHE B CD1 1 
ATOM   6686 C  CD2 . PHE B 1 361 ? 54.64973  -16.58130 -54.28400 1.000 78.72778  ? 361 PHE B CD2 1 
ATOM   6687 C  CE1 . PHE B 1 361 ? 53.65999  -18.31941 -56.18006 1.000 78.06477  ? 361 PHE B CE1 1 
ATOM   6688 C  CE2 . PHE B 1 361 ? 55.38295  -17.69256 -54.64755 1.000 76.45566  ? 361 PHE B CE2 1 
ATOM   6689 C  CZ  . PHE B 1 361 ? 54.88849  -18.56195 -55.59822 1.000 80.86745  ? 361 PHE B CZ  1 
ATOM   6690 N  N   . HIS B 1 362 ? 49.95326  -13.52924 -55.50702 1.000 69.78822  ? 362 HIS B N   1 
ATOM   6691 C  CA  . HIS B 1 362 ? 48.79762  -13.05910 -54.75301 1.000 59.84004  ? 362 HIS B CA  1 
ATOM   6692 C  C   . HIS B 1 362 ? 48.80750  -13.69846 -53.36981 1.000 61.49803  ? 362 HIS B C   1 
ATOM   6693 O  O   . HIS B 1 362 ? 49.24055  -14.84177 -53.20090 1.000 78.44726  ? 362 HIS B O   1 
ATOM   6694 C  CB  . HIS B 1 362 ? 47.49015  -13.42907 -55.46126 1.000 74.12947  ? 362 HIS B CB  1 
ATOM   6695 C  CG  . HIS B 1 362 ? 47.18810  -12.60754 -56.67630 1.000 72.50870  ? 362 HIS B CG  1 
ATOM   6696 N  ND1 . HIS B 1 362 ? 48.15179  -12.22930 -57.58568 1.000 62.25564  ? 362 HIS B ND1 1 
ATOM   6697 C  CD2 . HIS B 1 362 ? 46.01690  -12.11285 -57.14299 1.000 65.42591  ? 362 HIS B CD2 1 
ATOM   6698 C  CE1 . HIS B 1 362 ? 47.58895  -11.52679 -58.55346 1.000 65.43848  ? 362 HIS B CE1 1 
ATOM   6699 N  NE2 . HIS B 1 362 ? 46.29417  -11.44160 -58.30840 1.000 71.04813  ? 362 HIS B NE2 1 
ATOM   6700 N  N   . ALA B 1 363 ? 48.31501  -12.96481 -52.37010 1.000 63.89104  ? 363 ALA B N   1 
ATOM   6701 C  CA  . ALA B 1 363 ? 48.29754  -13.51279 -51.01813 1.000 64.34385  ? 363 ALA B CA  1 
ATOM   6702 C  C   . ALA B 1 363 ? 47.31437  -12.75398 -50.14012 1.000 57.11076  ? 363 ALA B C   1 
ATOM   6703 O  O   . ALA B 1 363 ? 47.30630  -11.51896 -50.13714 1.000 66.05768  ? 363 ALA B O   1 
ATOM   6704 C  CB  . ALA B 1 363 ? 49.69685  -13.47308 -50.39502 1.000 61.36903  ? 363 ALA B CB  1 
ATOM   6705 N  N   . ALA B 1 364 ? 46.49267  -13.50555 -49.40055 1.000 58.49461  ? 364 ALA B N   1 
ATOM   6706 C  CA  . ALA B 1 364 ? 45.69142  -12.97739 -48.29165 1.000 56.73651  ? 364 ALA B CA  1 
ATOM   6707 C  C   . ALA B 1 364 ? 44.67433  -11.93395 -48.75026 1.000 61.54284  ? 364 ALA B C   1 
ATOM   6708 O  O   . ALA B 1 364 ? 44.44395  -10.92855 -48.07493 1.000 81.94937  ? 364 ALA B O   1 
ATOM   6709 C  CB  . ALA B 1 364 ? 46.58919  -12.40636 -47.19146 1.000 54.65892  ? 364 ALA B CB  1 
ATOM   6710 N  N   . GLU B 1 365 ? 44.04833  -12.17519 -49.90108 1.000 58.39944  ? 365 GLU B N   1 
ATOM   6711 C  CA  . GLU B 1 365 ? 42.96741  -11.31847 -50.38920 1.000 55.44206  ? 365 GLU B CA  1 
ATOM   6712 C  C   . GLU B 1 365 ? 41.64364  -11.71730 -49.72715 1.000 59.86272  ? 365 GLU B C   1 
ATOM   6713 O  O   . GLU B 1 365 ? 40.68182  -12.13294 -50.37493 1.000 72.24451  ? 365 GLU B O   1 
ATOM   6714 C  CB  . GLU B 1 365 ? 42.88636  -11.40505 -51.90890 1.000 64.01346  ? 365 GLU B CB  1 
ATOM   6715 C  CG  . GLU B 1 365 ? 42.04079  -10.33027 -52.56860 1.000 73.03707  ? 365 GLU B CG  1 
ATOM   6716 C  CD  . GLU B 1 365 ? 41.91821  -10.53307 -54.06684 1.000 95.30663  ? 365 GLU B CD  1 
ATOM   6717 O  OE1 . GLU B 1 365 ? 42.28036  -11.62743 -54.55035 1.000 96.64569  ? 365 GLU B OE1 1 
ATOM   6718 O  OE2 . GLU B 1 365 ? 41.46286  -9.59818  -54.75973 1.000 96.26113  ? 365 GLU B OE2 1 
ATOM   6719 N  N   . THR B 1 366 ? 41.60613  -11.57720 -48.40142 1.000 59.08119  ? 366 THR B N   1 
ATOM   6720 C  CA  . THR B 1 366 ? 40.51851  -12.14660 -47.61963 1.000 69.99275  ? 366 THR B CA  1 
ATOM   6721 C  C   . THR B 1 366 ? 40.33025  -11.37486 -46.32173 1.000 63.12725  ? 366 THR B C   1 
ATOM   6722 O  O   . THR B 1 366 ? 41.24127  -10.69851 -45.83737 1.000 64.37635  ? 366 THR B O   1 
ATOM   6723 C  CB  . THR B 1 366 ? 40.78713  -13.62636 -47.30893 1.000 67.11667  ? 366 THR B CB  1 
ATOM   6724 O  OG1 . THR B 1 366 ? 39.68470  -14.17579 -46.57599 1.000 66.87612  ? 366 THR B OG1 1 
ATOM   6725 C  CG2 . THR B 1 366 ? 42.06662  -13.77553 -46.49380 1.000 63.79529  ? 366 THR B CG2 1 
ATOM   6726 N  N   . ASN B 1 367 ? 39.12168  -11.48677 -45.76472 1.000 51.72930  ? 367 ASN B N   1 
ATOM   6727 C  CA  . ASN B 1 367 ? 38.82957  -10.99149 -44.42644 1.000 61.91428  ? 367 ASN B CA  1 
ATOM   6728 C  C   . ASN B 1 367 ? 39.09318  -12.02849 -43.34358 1.000 69.46694  ? 367 ASN B C   1 
ATOM   6729 O  O   . ASN B 1 367 ? 39.07659  -11.68021 -42.15744 1.000 67.86676  ? 367 ASN B O   1 
ATOM   6730 C  CB  . ASN B 1 367 ? 37.36834  -10.53343 -44.32714 1.000 63.83626  ? 367 ASN B CB  1 
ATOM   6731 C  CG  . ASN B 1 367 ? 37.00611  -9.49830  -45.36982 1.000 68.71521  ? 367 ASN B CG  1 
ATOM   6732 O  OD1 . ASN B 1 367 ? 37.87440  -8.93094  -46.03098 1.000 76.23642  ? 367 ASN B OD1 1 
ATOM   6733 N  ND2 . ASN B 1 367 ? 35.71169  -9.23986  -45.51589 1.000 66.07373  ? 367 ASN B ND2 1 
ATOM   6734 N  N   . TRP B 1 368 ? 39.34666  -13.28107 -43.71623 1.000 66.82279  ? 368 TRP B N   1 
ATOM   6735 C  CA  . TRP B 1 368 ? 39.55077  -14.32647 -42.72451 1.000 65.59934  ? 368 TRP B CA  1 
ATOM   6736 C  C   . TRP B 1 368 ? 40.87899  -14.12922 -42.00279 1.000 69.43536  ? 368 TRP B C   1 
ATOM   6737 O  O   . TRP B 1 368 ? 41.81754  -13.52623 -42.53113 1.000 70.91814  ? 368 TRP B O   1 
ATOM   6738 C  CB  . TRP B 1 368 ? 39.52444  -15.70800 -43.37942 1.000 56.89106  ? 368 TRP B CB  1 
ATOM   6739 C  CG  . TRP B 1 368 ? 38.20654  -16.09004 -43.98344 1.000 60.65828  ? 368 TRP B CG  1 
ATOM   6740 C  CD1 . TRP B 1 368 ? 37.95344  -16.34238 -45.30004 1.000 59.48215  ? 368 TRP B CD1 1 
ATOM   6741 C  CD2 . TRP B 1 368 ? 36.96309  -16.27556 -43.29400 1.000 54.97376  ? 368 TRP B CD2 1 
ATOM   6742 N  NE1 . TRP B 1 368 ? 36.63163  -16.67135 -45.47483 1.000 58.10074  ? 368 TRP B NE1 1 
ATOM   6743 C  CE2 . TRP B 1 368 ? 36.00126  -16.63699 -44.25890 1.000 54.60630  ? 368 TRP B CE2 1 
ATOM   6744 C  CE3 . TRP B 1 368 ? 36.56955  -16.16917 -41.95628 1.000 49.08771  ? 368 TRP B CE3 1 
ATOM   6745 C  CZ2 . TRP B 1 368 ? 34.67150  -16.89227 -43.92927 1.000 47.75595  ? 368 TRP B CZ2 1 
ATOM   6746 C  CZ3 . TRP B 1 368 ? 35.24766  -16.42329 -41.63045 1.000 52.92217  ? 368 TRP B CZ3 1 
ATOM   6747 C  CH2 . TRP B 1 368 ? 34.31498  -16.78008 -42.61327 1.000 55.88708  ? 368 TRP B CH2 1 
ATOM   6748 N  N   . GLN B 1 369 ? 40.95082  -14.64531 -40.77919 1.000 59.76703  ? 369 GLN B N   1 
ATOM   6749 C  CA  . GLN B 1 369 ? 42.14286  -14.53675 -39.95245 1.000 53.46085  ? 369 GLN B CA  1 
ATOM   6750 C  C   . GLN B 1 369 ? 42.52356  -15.91875 -39.44284 1.000 66.02651  ? 369 GLN B C   1 
ATOM   6751 O  O   . GLN B 1 369 ? 41.66039  -16.67671 -38.98783 1.000 68.50319  ? 369 GLN B O   1 
ATOM   6752 C  CB  . GLN B 1 369 ? 41.91218  -13.57296 -38.78103 1.000 58.57753  ? 369 GLN B CB  1 
ATOM   6753 C  CG  . GLN B 1 369 ? 43.16321  -13.22536 -37.98841 1.000 64.92665  ? 369 GLN B CG  1 
ATOM   6754 C  CD  . GLN B 1 369 ? 42.87456  -12.26433 -36.85010 1.000 67.54907  ? 369 GLN B CD  1 
ATOM   6755 O  OE1 . GLN B 1 369 ? 41.73944  -11.82223 -36.67160 1.000 61.83895  ? 369 GLN B OE1 1 
ATOM   6756 N  NE2 . GLN B 1 369 ? 43.90203  -11.93507 -36.07442 1.000 70.09166  ? 369 GLN B NE2 1 
ATOM   6757 N  N   . GLU B 1 370 ? 43.81663  -16.23723 -39.52170 1.000 71.24340  ? 370 GLU B N   1 
ATOM   6758 C  CA  . GLU B 1 370 ? 44.35535  -17.53708 -39.11956 1.000 65.03273  ? 370 GLU B CA  1 
ATOM   6759 C  C   . GLU B 1 370 ? 43.64858  -18.68184 -39.84446 1.000 63.60653  ? 370 GLU B C   1 
ATOM   6760 O  O   . GLU B 1 370 ? 43.25173  -19.67979 -39.24102 1.000 74.31985  ? 370 GLU B O   1 
ATOM   6761 C  CB  . GLU B 1 370 ? 44.28479  -17.71329 -37.60019 1.000 68.98132  ? 370 GLU B CB  1 
ATOM   6762 C  CG  . GLU B 1 370 ? 45.24135  -16.80685 -36.84521 1.000 72.36859  ? 370 GLU B CG  1 
ATOM   6763 C  CD  . GLU B 1 370 ? 45.12687  -16.95550 -35.34383 1.000 80.65277  ? 370 GLU B CD  1 
ATOM   6764 O  OE1 . GLU B 1 370 ? 44.27698  -17.74810 -34.88888 1.000 79.09675  ? 370 GLU B OE1 1 
ATOM   6765 O  OE2 . GLU B 1 370 ? 45.88609  -16.27787 -34.61969 1.000 76.09042  ? 370 GLU B OE2 1 
ATOM   6766 N  N   . THR B 1 371 ? 43.48718  -18.52440 -41.15382 1.000 62.18501  ? 371 THR B N   1 
ATOM   6767 C  CA  . THR B 1 371 ? 42.97995  -19.57173 -42.03011 1.000 58.43577  ? 371 THR B CA  1 
ATOM   6768 C  C   . THR B 1 371 ? 44.06220  -19.95978 -43.03304 1.000 68.07088  ? 371 THR B C   1 
ATOM   6769 O  O   . THR B 1 371 ? 45.15124  -19.38265 -43.06275 1.000 61.60001  ? 371 THR B O   1 
ATOM   6770 C  CB  . THR B 1 371 ? 41.70703  -19.12252 -42.75688 1.000 52.50566  ? 371 THR B CB  1 
ATOM   6771 O  OG1 . THR B 1 371 ? 41.97413  -17.93062 -43.50568 1.000 64.99529  ? 371 THR B OG1 1 
ATOM   6772 C  CG2 . THR B 1 371 ? 40.58316  -18.85936 -41.76416 1.000 64.43304  ? 371 THR B CG2 1 
ATOM   6773 N  N   . GLU B 1 372 ? 43.74878  -20.95870 -43.86147 1.000 78.98768  ? 372 GLU B N   1 
ATOM   6774 C  CA  . GLU B 1 372 ? 44.68052  -21.37026 -44.90738 1.000 75.75414  ? 372 GLU B CA  1 
ATOM   6775 C  C   . GLU B 1 372 ? 44.92933  -20.23856 -45.89651 1.000 69.90942  ? 372 GLU B C   1 
ATOM   6776 O  O   . GLU B 1 372 ? 46.06732  -20.01864 -46.32981 1.000 62.13623  ? 372 GLU B O   1 
ATOM   6777 C  CB  . GLU B 1 372 ? 44.14451  -22.60532 -45.62752 1.000 78.81382  ? 372 GLU B CB  1 
ATOM   6778 C  CG  . GLU B 1 372 ? 45.18456  -23.68542 -45.85910 1.000 92.10476  ? 372 GLU B CG  1 
ATOM   6779 C  CD  . GLU B 1 372 ? 44.56542  -25.01308 -46.24652 1.000 89.69044  ? 372 GLU B CD  1 
ATOM   6780 O  OE1 . GLU B 1 372 ? 43.60559  -25.01516 -47.04621 1.000 88.52831  ? 372 GLU B OE1 1 
ATOM   6781 O  OE2 . GLU B 1 372 ? 45.03105  -26.05475 -45.73870 1.000 97.49943  ? 372 GLU B OE2 1 
ATOM   6782 N  N   . VAL B 1 373 ? 43.87067  -19.51687 -46.27182 1.000 67.01296  ? 373 VAL B N   1 
ATOM   6783 C  CA  . VAL B 1 373 ? 44.01629  -18.37414 -47.17081 1.000 72.94178  ? 373 VAL B CA  1 
ATOM   6784 C  C   . VAL B 1 373 ? 44.92341  -17.32578 -46.54437 1.000 69.37089  ? 373 VAL B C   1 
ATOM   6785 O  O   . VAL B 1 373 ? 45.84978  -16.80942 -47.18098 1.000 60.18069  ? 373 VAL B O   1 
ATOM   6786 C  CB  . VAL B 1 373 ? 42.63631  -17.77655 -47.50094 1.000 61.49030  ? 373 VAL B CB  1 
ATOM   6787 C  CG1 . VAL B 1 373 ? 42.74130  -16.79228 -48.65536 1.000 68.24118  ? 373 VAL B CG1 1 
ATOM   6788 C  CG2 . VAL B 1 373 ? 41.62403  -18.86905 -47.78899 1.000 73.82102  ? 373 VAL B CG2 1 
ATOM   6789 N  N   . ASP B 1 374 ? 44.66386  -17.00347 -45.27810 1.000 79.00615  ? 374 ASP B N   1 
ATOM   6790 C  CA  . ASP B 1 374 ? 45.38223  -15.93822 -44.59165 1.000 68.15061  ? 374 ASP B CA  1 
ATOM   6791 C  C   . ASP B 1 374 ? 46.86574  -16.25493 -44.43573 1.000 71.08371  ? 374 ASP B C   1 
ATOM   6792 O  O   . ASP B 1 374 ? 47.69996  -15.34135 -44.45103 1.000 58.25121  ? 374 ASP B O   1 
ATOM   6793 C  CB  . ASP B 1 374 ? 44.72194  -15.70890 -43.23304 1.000 58.82780  ? 374 ASP B CB  1 
ATOM   6794 C  CG  . ASP B 1 374 ? 45.41083  -14.65199 -42.41640 1.000 73.62002  ? 374 ASP B CG  1 
ATOM   6795 O  OD1 . ASP B 1 374 ? 46.04971  -13.74884 -42.99622 1.000 87.04507  ? 374 ASP B OD1 1 
ATOM   6796 O  OD2 . ASP B 1 374 ? 45.30685  -14.73317 -41.17826 1.000 74.67302  ? 374 ASP B OD2 1 
ATOM   6797 N  N   . TYR B 1 375 ? 47.21487  -17.53336 -44.30092 1.000 75.42373  ? 375 TYR B N   1 
ATOM   6798 C  CA  . TYR B 1 375 ? 48.58523  -17.95604 -44.04278 1.000 69.20749  ? 375 TYR B CA  1 
ATOM   6799 C  C   . TYR B 1 375 ? 49.42227  -18.10454 -45.30577 1.000 71.31125  ? 375 TYR B C   1 
ATOM   6800 O  O   . TYR B 1 375 ? 50.58481  -18.51350 -45.21336 1.000 78.82317  ? 375 TYR B O   1 
ATOM   6801 C  CB  . TYR B 1 375 ? 48.59157  -19.27770 -43.26288 1.000 58.30930  ? 375 TYR B CB  1 
ATOM   6802 C  CG  . TYR B 1 375 ? 48.43694  -19.10396 -41.76673 1.000 61.76121  ? 375 TYR B CG  1 
ATOM   6803 C  CD1 . TYR B 1 375 ? 49.24547  -18.21852 -41.06458 1.000 63.70649  ? 375 TYR B CD1 1 
ATOM   6804 C  CD2 . TYR B 1 375 ? 47.47217  -19.81105 -41.05880 1.000 60.91496  ? 375 TYR B CD2 1 
ATOM   6805 C  CE1 . TYR B 1 375 ? 49.10462  -18.04924 -39.69801 1.000 62.63218  ? 375 TYR B CE1 1 
ATOM   6806 C  CE2 . TYR B 1 375 ? 47.32296  -19.64640 -39.69245 1.000 58.45591  ? 375 TYR B CE2 1 
ATOM   6807 C  CZ  . TYR B 1 375 ? 48.14178  -18.76567 -39.01823 1.000 58.75424  ? 375 TYR B CZ  1 
ATOM   6808 O  OH  . TYR B 1 375 ? 47.99566  -18.60191 -37.66002 1.000 70.77444  ? 375 TYR B OH  1 
ATOM   6809 N  N   . ASN B 1 376 ? 48.86977  -17.79058 -46.47968 1.000 64.68801  ? 376 ASN B N   1 
ATOM   6810 C  CA  . ASN B 1 376 ? 49.65811  -17.86376 -47.70595 1.000 66.37099  ? 376 ASN B CA  1 
ATOM   6811 C  C   . ASN B 1 376 ? 50.83093  -16.89457 -47.68722 1.000 77.18689  ? 376 ASN B C   1 
ATOM   6812 O  O   . ASN B 1 376 ? 51.75252  -17.03544 -48.49878 1.000 81.12308  ? 376 ASN B O   1 
ATOM   6813 C  CB  . ASN B 1 376 ? 48.78288  -17.58092 -48.92904 1.000 68.18345  ? 376 ASN B CB  1 
ATOM   6814 C  CG  . ASN B 1 376 ? 47.78156  -18.68447 -49.20336 1.000 71.37191  ? 376 ASN B CG  1 
ATOM   6815 O  OD1 . ASN B 1 376 ? 47.91202  -19.80187 -48.70526 1.000 79.86014  ? 376 ASN B OD1 1 
ATOM   6816 N  ND2 . ASN B 1 376 ? 46.77330  -18.37416 -50.01403 1.000 60.66817  ? 376 ASN B ND2 1 
ATOM   6817 N  N   . LEU B 1 377 ? 50.81077  -15.91572 -46.77880 1.000 75.87741  ? 377 LEU B N   1 
ATOM   6818 C  CA  . LEU B 1 377 ? 51.89931  -14.94989 -46.68152 1.000 76.80171  ? 377 LEU B CA  1 
ATOM   6819 C  C   . LEU B 1 377 ? 53.18874  -15.60313 -46.19896 1.000 75.77403  ? 377 LEU B C   1 
ATOM   6820 O  O   . LEU B 1 377 ? 54.27957  -15.23938 -46.65291 1.000 73.10188  ? 377 LEU B O   1 
ATOM   6821 C  CB  . LEU B 1 377 ? 51.49263  -13.80982 -45.75314 1.000 71.05309  ? 377 LEU B CB  1 
ATOM   6822 C  CG  . LEU B 1 377 ? 50.29968  -12.99215 -46.24709 1.000 60.64038  ? 377 LEU B CG  1 
ATOM   6823 C  CD1 . LEU B 1 377 ? 49.55340  -12.38293 -45.07491 1.000 75.97795  ? 377 LEU B CD1 1 
ATOM   6824 C  CD2 . LEU B 1 377 ? 50.75711  -11.91111 -47.21643 1.000 51.15582  ? 377 LEU B CD2 1 
ATOM   6825 N  N   . ALA B 1 378 ? 53.09068  -16.55440 -45.26664 1.000 73.89518  ? 378 ALA B N   1 
ATOM   6826 C  CA  . ALA B 1 378 ? 54.28888  -17.24705 -44.80156 1.000 81.62685  ? 378 ALA B CA  1 
ATOM   6827 C  C   . ALA B 1 378 ? 54.95356  -18.00922 -45.93859 1.000 80.91349  ? 378 ALA B C   1 
ATOM   6828 O  O   . ALA B 1 378 ? 56.18395  -18.00756 -46.06323 1.000 85.69891  ? 378 ALA B O   1 
ATOM   6829 C  CB  . ALA B 1 378 ? 53.94433  -18.19141 -43.65052 1.000 57.97549  ? 378 ALA B CB  1 
ATOM   6830 N  N   . ASP B 1 379 ? 54.15368  -18.67417 -46.77353 1.000 80.55364  ? 379 ASP B N   1 
ATOM   6831 C  CA  . ASP B 1 379 ? 54.70136  -19.34817 -47.94445 1.000 75.67695  ? 379 ASP B CA  1 
ATOM   6832 C  C   . ASP B 1 379 ? 55.32272  -18.35194 -48.91567 1.000 79.99687  ? 379 ASP B C   1 
ATOM   6833 O  O   . ASP B 1 379 ? 56.40141  -18.60096 -49.46680 1.000 75.98710  ? 379 ASP B O   1 
ATOM   6834 C  CB  . ASP B 1 379 ? 53.60850  -20.16217 -48.63585 1.000 74.28802  ? 379 ASP B CB  1 
ATOM   6835 C  CG  . ASP B 1 379 ? 53.05679  -21.26552 -47.75403 1.000 85.37479  ? 379 ASP B CG  1 
ATOM   6836 O  OD1 . ASP B 1 379 ? 53.85325  -22.08543 -47.25193 1.000 88.92272  ? 379 ASP B OD1 1 
ATOM   6837 O  OD2 . ASP B 1 379 ? 51.82423  -21.30641 -47.55698 1.000 93.46514  ? 379 ASP B OD2 1 
ATOM   6838 N  N   . ALA B 1 380 ? 54.65292  -17.21893 -49.14099 1.000 72.06059  ? 380 ALA B N   1 
ATOM   6839 C  CA  . ALA B 1 380 ? 55.16198  -16.23094 -50.08698 1.000 71.96199  ? 380 ALA B CA  1 
ATOM   6840 C  C   . ALA B 1 380 ? 56.46720  -15.61388 -49.60103 1.000 73.47155  ? 380 ALA B C   1 
ATOM   6841 O  O   . ALA B 1 380 ? 57.39417  -15.40440 -50.39188 1.000 76.43566  ? 380 ALA B O   1 
ATOM   6842 C  CB  . ALA B 1 380 ? 54.11213  -15.14595 -50.32570 1.000 67.13089  ? 380 ALA B CB  1 
ATOM   6843 N  N   . LEU B 1 381 ? 56.55799  -15.31704 -48.30312 1.000 78.80161  ? 381 LEU B N   1 
ATOM   6844 C  CA  . LEU B 1 381 ? 57.75334  -14.67347 -47.77100 1.000 76.78333  ? 381 LEU B CA  1 
ATOM   6845 C  C   . LEU B 1 381 ? 58.94480  -15.62112 -47.74975 1.000 73.52343  ? 381 LEU B C   1 
ATOM   6846 O  O   . LEU B 1 381 ? 60.08977  -15.17700 -47.89259 1.000 75.05692  ? 381 LEU B O   1 
ATOM   6847 C  CB  . LEU B 1 381 ? 57.47479  -14.13011 -46.37051 1.000 79.38041  ? 381 LEU B CB  1 
ATOM   6848 C  CG  . LEU B 1 381 ? 56.55538  -12.90586 -46.33665 1.000 72.79659  ? 381 LEU B CG  1 
ATOM   6849 C  CD1 . LEU B 1 381 ? 56.31984  -12.43906 -44.90573 1.000 65.13190  ? 381 LEU B CD1 1 
ATOM   6850 C  CD2 . LEU B 1 381 ? 57.10966  -11.77566 -47.20085 1.000 71.99481  ? 381 LEU B CD2 1 
ATOM   6851 N  N   . LEU B 1 382 ? 58.70271  -16.92000 -47.57107 1.000 77.48152  ? 382 LEU B N   1 
ATOM   6852 C  CA  . LEU B 1 382 ? 59.79793  -17.88146 -47.57182 1.000 74.29988  ? 382 LEU B CA  1 
ATOM   6853 C  C   . LEU B 1 382 ? 60.24042  -18.25335 -48.98002 1.000 82.45858  ? 382 LEU B C   1 
ATOM   6854 O  O   . LEU B 1 382 ? 61.39011  -18.66347 -49.17371 1.000 88.89036  ? 382 LEU B O   1 
ATOM   6855 C  CB  . LEU B 1 382 ? 59.38919  -19.13198 -46.79649 1.000 71.57955  ? 382 LEU B CB  1 
ATOM   6856 C  CG  . LEU B 1 382 ? 59.29579  -18.91524 -45.28962 1.000 61.98749  ? 382 LEU B CG  1 
ATOM   6857 C  CD1 . LEU B 1 382 ? 58.98948  -20.21890 -44.59900 1.000 66.91970  ? 382 LEU B CD1 1 
ATOM   6858 C  CD2 . LEU B 1 382 ? 60.59596  -18.32354 -44.77443 1.000 65.77687  ? 382 LEU B CD2 1 
ATOM   6859 N  N   . LEU B 1 383 ? 59.35748  -18.11665 -49.96583 1.000 78.28775  ? 383 LEU B N   1 
ATOM   6860 C  CA  . LEU B 1 383 ? 59.69279  -18.41517 -51.35236 1.000 72.64899  ? 383 LEU B CA  1 
ATOM   6861 C  C   . LEU B 1 383 ? 60.35430  -17.24483 -52.06842 1.000 65.89251  ? 383 LEU B C   1 
ATOM   6862 O  O   . LEU B 1 383 ? 60.48365  -17.28642 -53.29671 1.000 76.22783  ? 383 LEU B O   1 
ATOM   6863 C  CB  . LEU B 1 383 ? 58.43965  -18.85304 -52.11556 1.000 69.18294  ? 383 LEU B CB  1 
ATOM   6864 C  CG  . LEU B 1 383 ? 57.95078  -20.27062 -51.82024 1.000 66.43236  ? 383 LEU B CG  1 
ATOM   6865 C  CD1 . LEU B 1 383 ? 56.65296  -20.55789 -52.55927 1.000 72.53307  ? 383 LEU B CD1 1 
ATOM   6866 C  CD2 . LEU B 1 383 ? 59.01921  -21.29129 -52.18541 1.000 72.16078  ? 383 LEU B CD2 1 
ATOM   6867 N  N   . ASN B 1 384 ? 60.77282  -16.21583 -51.32978 1.000 67.90989  ? 384 ASN B N   1 
ATOM   6868 C  CA  . ASN B 1 384 ? 61.46797  -15.05662 -51.89361 1.000 84.44013  ? 384 ASN B CA  1 
ATOM   6869 C  C   . ASN B 1 384 ? 60.63608  -14.37256 -52.97819 1.000 75.07123  ? 384 ASN B C   1 
ATOM   6870 O  O   . ASN B 1 384 ? 61.12599  -14.05327 -54.06325 1.000 84.33094  ? 384 ASN B O   1 
ATOM   6871 C  CB  . ASN B 1 384 ? 62.84766  -15.44739 -52.43085 1.000 80.76918  ? 384 ASN B CB  1 
ATOM   6872 C  CG  . ASN B 1 384 ? 63.91671  -15.45093 -51.35393 1.000 91.96231  ? 384 ASN B CG  1 
ATOM   6873 O  OD1 . ASN B 1 384 ? 63.98879  -16.36721 -50.53409 1.000 84.31099  ? 384 ASN B OD1 1 
ATOM   6874 N  ND2 . ASN B 1 384 ? 64.76480  -14.42875 -51.36142 1.000 99.19382  ? 384 ASN B ND2 1 
ATOM   6875 N  N   . THR B 1 385 ? 59.36225  -14.14408 -52.67749 1.000 63.66597  ? 385 THR B N   1 
ATOM   6876 C  CA  . THR B 1 385 ? 58.52983  -13.39591 -53.60324 1.000 70.35776  ? 385 THR B CA  1 
ATOM   6877 C  C   . THR B 1 385 ? 59.02534  -11.95698 -53.68766 1.000 71.71721  ? 385 THR B C   1 
ATOM   6878 O  O   . THR B 1 385 ? 59.51548  -11.38284 -52.71101 1.000 81.85874  ? 385 THR B O   1 
ATOM   6879 C  CB  . THR B 1 385 ? 57.05894  -13.43766 -53.17960 1.000 66.73589  ? 385 THR B CB  1 
ATOM   6880 O  OG1 . THR B 1 385 ? 56.23903  -12.88978 -54.21902 1.000 67.99656  ? 385 THR B OG1 1 
ATOM   6881 C  CG2 . THR B 1 385 ? 56.82731  -12.64450 -51.89889 1.000 72.45780  ? 385 THR B CG2 1 
ATOM   6882 N  N   . THR B 1 386 ? 58.91565  -11.38086 -54.88235 1.000 68.38319  ? 386 THR B N   1 
ATOM   6883 C  CA  . THR B 1 386 ? 59.40557  -10.02942 -55.11208 1.000 69.79727  ? 386 THR B CA  1 
ATOM   6884 C  C   . THR B 1 386 ? 58.37141  -8.98393  -54.72144 1.000 75.57641  ? 386 THR B C   1 
ATOM   6885 O  O   . THR B 1 386 ? 58.73079  -7.92489  -54.19555 1.000 76.23053  ? 386 THR B O   1 
ATOM   6886 C  CB  . THR B 1 386 ? 59.81271  -9.86246  -56.57633 1.000 62.70620  ? 386 THR B CB  1 
ATOM   6887 O  OG1 . THR B 1 386 ? 60.48969  -11.04650 -57.02073 1.000 86.52435  ? 386 THR B OG1 1 
ATOM   6888 C  CG2 . THR B 1 386 ? 60.75098  -8.67872  -56.73739 1.000 57.46891  ? 386 THR B CG2 1 
ATOM   6889 N  N   . ARG B 1 387 ? 57.09443  -9.27060  -54.96156 1.000 73.98838  ? 387 ARG B N   1 
ATOM   6890 C  CA  . ARG B 1 387 ? 56.00460  -8.41396  -54.52287 1.000 70.19515  ? 387 ARG B CA  1 
ATOM   6891 C  C   . ARG B 1 387 ? 54.80952  -9.28851  -54.17472 1.000 64.67664  ? 387 ARG B C   1 
ATOM   6892 O  O   . ARG B 1 387 ? 54.69364  -10.42844 -54.63245 1.000 75.11183  ? 387 ARG B O   1 
ATOM   6893 C  CB  . ARG B 1 387 ? 55.61463  -7.37753  -55.58800 1.000 76.44567  ? 387 ARG B CB  1 
ATOM   6894 C  CG  . ARG B 1 387 ? 56.59214  -6.22308  -55.75310 1.000 73.78835  ? 387 ARG B CG  1 
ATOM   6895 C  CD  . ARG B 1 387 ? 55.98703  -5.12402  -56.60712 1.000 72.65950  ? 387 ARG B CD  1 
ATOM   6896 N  NE  . ARG B 1 387 ? 55.37101  -5.66141  -57.81338 1.000 71.40507  ? 387 ARG B NE  1 
ATOM   6897 C  CZ  . ARG B 1 387 ? 56.00366  -5.83240  -58.96542 1.000 75.05340  ? 387 ARG B CZ  1 
ATOM   6898 N  NH1 . ARG B 1 387 ? 57.27791  -5.50689  -59.10947 1.000 70.62265  ? 387 ARG B NH1 1 
ATOM   6899 N  NH2 . ARG B 1 387 ? 55.34164  -6.34495  -59.99872 1.000 67.70778  ? 387 ARG B NH2 1 
ATOM   6900 N  N   . VAL B 1 388 ? 53.92015  -8.73810  -53.35446 1.000 64.43230  ? 388 VAL B N   1 
ATOM   6901 C  CA  . VAL B 1 388 ? 52.69737  -9.41386  -52.94579 1.000 63.58902  ? 388 VAL B CA  1 
ATOM   6902 C  C   . VAL B 1 388 ? 51.51271  -8.65172  -53.52038 1.000 68.43364  ? 388 VAL B C   1 
ATOM   6903 O  O   . VAL B 1 388 ? 51.52548  -7.41897  -53.60817 1.000 80.19616  ? 388 VAL B O   1 
ATOM   6904 C  CB  . VAL B 1 388 ? 52.59312  -9.51974  -51.40927 1.000 61.97628  ? 388 VAL B CB  1 
ATOM   6905 C  CG1 . VAL B 1 388 ? 51.35986  -10.31165 -51.00713 1.000 63.58626  ? 388 VAL B CG1 1 
ATOM   6906 C  CG2 . VAL B 1 388 ? 53.84796  -10.15486 -50.83394 1.000 61.57266  ? 388 VAL B CG2 1 
ATOM   6907 N  N   . GLY B 1 389 ? 50.48593  -9.39504  -53.92576 1.000 59.87192  ? 389 GLY B N   1 
ATOM   6908 C  CA  . GLY B 1 389 ? 49.27193  -8.80726  -54.45951 1.000 54.02791  ? 389 GLY B CA  1 
ATOM   6909 C  C   . GLY B 1 389 ? 48.22714  -8.63895  -53.37210 1.000 61.74194  ? 389 GLY B C   1 
ATOM   6910 O  O   . GLY B 1 389 ? 47.94731  -9.57156  -52.61520 1.000 57.05433  ? 389 GLY B O   1 
ATOM   6911 N  N   . HIS B 1 390 ? 47.65838  -7.43078  -53.30797 1.000 75.69502  ? 390 HIS B N   1 
ATOM   6912 C  CA  . HIS B 1 390 ? 46.60917  -7.05225  -52.36332 1.000 62.87935  ? 390 HIS B CA  1 
ATOM   6913 C  C   . HIS B 1 390 ? 47.10015  -7.04073  -50.91958 1.000 66.96627  ? 390 HIS B C   1 
ATOM   6914 O  O   . HIS B 1 390 ? 47.23275  -5.96814  -50.32125 1.000 69.65819  ? 390 HIS B O   1 
ATOM   6915 C  CB  . HIS B 1 390 ? 45.39285  -7.97066  -52.50739 1.000 58.80871  ? 390 HIS B CB  1 
ATOM   6916 C  CG  . HIS B 1 390 ? 44.71638  -7.86684  -53.83828 1.000 70.97477  ? 390 HIS B CG  1 
ATOM   6917 N  ND1 . HIS B 1 390 ? 44.92516  -8.77604  -54.85258 1.000 71.65367  ? 390 HIS B ND1 1 
ATOM   6918 C  CD2 . HIS B 1 390 ? 43.84314  -6.95389  -54.32504 1.000 77.56390  ? 390 HIS B CD2 1 
ATOM   6919 C  CE1 . HIS B 1 390 ? 44.20423  -8.43171  -55.90467 1.000 73.93657  ? 390 HIS B CE1 1 
ATOM   6920 N  NE2 . HIS B 1 390 ? 43.53865  -7.32930  -55.61089 1.000 84.38549  ? 390 HIS B NE2 1 
ATOM   6921 N  N   . GLY B 1 391 ? 47.35162  -8.21459  -50.34660 1.000 63.32177  ? 391 GLY B N   1 
ATOM   6922 C  CA  . GLY B 1 391 ? 47.84487  -8.28846  -48.97905 1.000 60.22765  ? 391 GLY B CA  1 
ATOM   6923 C  C   . GLY B 1 391 ? 46.89061  -7.70073  -47.96357 1.000 67.84158  ? 391 GLY B C   1 
ATOM   6924 O  O   . GLY B 1 391 ? 47.32698  -7.04397  -47.01015 1.000 69.47565  ? 391 GLY B O   1 
ATOM   6925 N  N   . PHE B 1 392 ? 45.58694  -7.92349  -48.14980 1.000 62.92493  ? 392 PHE B N   1 
ATOM   6926 C  CA  . PHE B 1 392 ? 44.58687  -7.27783  -47.30611 1.000 61.85589  ? 392 PHE B CA  1 
ATOM   6927 C  C   . PHE B 1 392 ? 44.72334  -7.68842  -45.84597 1.000 71.54416  ? 392 PHE B C   1 
ATOM   6928 O  O   . PHE B 1 392 ? 44.38200  -6.90981  -44.94922 1.000 77.95180  ? 392 PHE B O   1 
ATOM   6929 C  CB  . PHE B 1 392 ? 43.18546  -7.60005  -47.82975 1.000 52.36220  ? 392 PHE B CB  1 
ATOM   6930 C  CG  . PHE B 1 392 ? 42.13889  -6.59965  -47.43051 1.000 53.32657  ? 392 PHE B CG  1 
ATOM   6931 C  CD1 . PHE B 1 392 ? 42.18413  -5.30216  -47.91171 1.000 57.29435  ? 392 PHE B CD1 1 
ATOM   6932 C  CD2 . PHE B 1 392 ? 41.09901  -6.96167  -46.59037 1.000 57.19092  ? 392 PHE B CD2 1 
ATOM   6933 C  CE1 . PHE B 1 392 ? 41.21999  -4.37945  -47.55187 1.000 54.82970  ? 392 PHE B CE1 1 
ATOM   6934 C  CE2 . PHE B 1 392 ? 40.13064  -6.04407  -46.22764 1.000 53.27782  ? 392 PHE B CE2 1 
ATOM   6935 C  CZ  . PHE B 1 392 ? 40.19142  -4.75146  -46.70936 1.000 57.05436  ? 392 PHE B CZ  1 
ATOM   6936 N  N   . ALA B 1 393 ? 45.22530  -8.89441  -45.58289 1.000 59.02896  ? 393 ALA B N   1 
ATOM   6937 C  CA  . ALA B 1 393 ? 45.36355  -9.39498  -44.22038 1.000 68.16300  ? 393 ALA B CA  1 
ATOM   6938 C  C   . ALA B 1 393 ? 46.81398  -9.40869  -43.74704 1.000 70.74376  ? 393 ALA B C   1 
ATOM   6939 O  O   . ALA B 1 393 ? 47.15285  -10.15349 -42.82412 1.000 75.80746  ? 393 ALA B O   1 
ATOM   6940 C  CB  . ALA B 1 393 ? 44.75798  -10.79443 -44.10127 1.000 64.85530  ? 393 ALA B CB  1 
ATOM   6941 N  N   . LEU B 1 394 ? 47.68007  -8.59702  -44.35501 1.000 71.22916  ? 394 LEU B N   1 
ATOM   6942 C  CA  . LEU B 1 394 ? 49.05302  -8.50644  -43.87009 1.000 70.15289  ? 394 LEU B CA  1 
ATOM   6943 C  C   . LEU B 1 394 ? 49.12682  -7.73302  -42.56063 1.000 67.30353  ? 394 LEU B C   1 
ATOM   6944 O  O   . LEU B 1 394 ? 49.97424  -8.03167  -41.71265 1.000 63.68160  ? 394 LEU B O   1 
ATOM   6945 C  CB  . LEU B 1 394 ? 49.95318  -7.86086  -44.92692 1.000 52.63316  ? 394 LEU B CB  1 
ATOM   6946 C  CG  . LEU B 1 394 ? 51.42991  -7.72790  -44.55768 1.000 55.68030  ? 394 LEU B CG  1 
ATOM   6947 C  CD1 . LEU B 1 394 ? 52.02769  -9.10045  -44.32044 1.000 62.54098  ? 394 LEU B CD1 1 
ATOM   6948 C  CD2 . LEU B 1 394 ? 52.20924  -6.98347  -45.63194 1.000 46.42063  ? 394 LEU B CD2 1 
ATOM   6949 N  N   . ILE B 1 395 ? 48.24567  -6.74660  -42.37542 1.000 74.38070  ? 395 ILE B N   1 
ATOM   6950 C  CA  . ILE B 1 395 ? 48.24071  -5.95987  -41.14862 1.000 74.68992  ? 395 ILE B CA  1 
ATOM   6951 C  C   . ILE B 1 395 ? 47.86355  -6.80021  -39.93333 1.000 73.35538  ? 395 ILE B C   1 
ATOM   6952 O  O   . ILE B 1 395 ? 48.19899  -6.43162  -38.80252 1.000 70.89033  ? 395 ILE B O   1 
ATOM   6953 C  CB  . ILE B 1 395 ? 47.29788  -4.75043  -41.30043 1.000 66.15573  ? 395 ILE B CB  1 
ATOM   6954 C  CG1 . ILE B 1 395 ? 47.54253  -3.72753  -40.18791 1.000 62.15087  ? 395 ILE B CG1 1 
ATOM   6955 C  CG2 . ILE B 1 395 ? 45.83976  -5.19497  -41.30844 1.000 82.68978  ? 395 ILE B CG2 1 
ATOM   6956 C  CD1 . ILE B 1 395 ? 48.92115  -3.10688  -40.22678 1.000 71.85491  ? 395 ILE B CD1 1 
ATOM   6957 N  N   . LYS B 1 396 ? 47.18507  -7.93156  -40.13455 1.000 67.31428  ? 396 LYS B N   1 
ATOM   6958 C  CA  . LYS B 1 396 ? 46.78226  -8.79560  -39.03119 1.000 61.13222  ? 396 LYS B CA  1 
ATOM   6959 C  C   . LYS B 1 396 ? 47.89919  -9.71304  -38.54980 1.000 66.31719  ? 396 LYS B C   1 
ATOM   6960 O  O   . LYS B 1 396 ? 47.67992  -10.48087 -37.60624 1.000 70.81008  ? 396 LYS B O   1 
ATOM   6961 C  CB  . LYS B 1 396 ? 45.56491  -9.63890  -39.42613 1.000 58.23755  ? 396 LYS B CB  1 
ATOM   6962 C  CG  . LYS B 1 396 ? 44.31320  -8.82810  -39.73391 1.000 66.03938  ? 396 LYS B CG  1 
ATOM   6963 C  CD  . LYS B 1 396 ? 43.07061  -9.70744  -39.76005 1.000 63.98336  ? 396 LYS B CD  1 
ATOM   6964 C  CE  . LYS B 1 396 ? 41.83146  -8.91543  -40.15306 1.000 66.50827  ? 396 LYS B CE  1 
ATOM   6965 N  NZ  . LYS B 1 396 ? 40.59938  -9.75237  -40.09739 1.000 57.65013  ? 396 LYS B NZ  1 
ATOM   6966 N  N   . HIS B 1 397 ? 49.07587  -9.66687  -39.16882 1.000 69.03408  ? 397 HIS B N   1 
ATOM   6967 C  CA  . HIS B 1 397 ? 50.19147  -10.53984 -38.80114 1.000 69.75505  ? 397 HIS B CA  1 
ATOM   6968 C  C   . HIS B 1 397 ? 51.42472  -9.71704  -38.46281 1.000 71.90000  ? 397 HIS B C   1 
ATOM   6969 O  O   . HIS B 1 397 ? 52.11098  -9.21604  -39.37177 1.000 77.60135  ? 397 HIS B O   1 
ATOM   6970 C  CB  . HIS B 1 397 ? 50.48764  -11.52406 -39.92626 1.000 72.26583  ? 397 HIS B CB  1 
ATOM   6971 C  CG  . HIS B 1 397 ? 49.42512  -12.55926 -40.09594 1.000 71.71647  ? 397 HIS B CG  1 
ATOM   6972 N  ND1 . HIS B 1 397 ? 49.52572  -13.82358 -39.55792 1.000 91.26894  ? 397 HIS B ND1 1 
ATOM   6973 C  CD2 . HIS B 1 397 ? 48.22238  -12.50629 -40.71255 1.000 58.52762  ? 397 HIS B CD2 1 
ATOM   6974 C  CE1 . HIS B 1 397 ? 48.43928  -14.51257 -39.85384 1.000 83.33827  ? 397 HIS B CE1 1 
ATOM   6975 N  NE2 . HIS B 1 397 ? 47.63327  -13.73515 -40.55241 1.000 72.71807  ? 397 HIS B NE2 1 
ATOM   6976 N  N   . PRO B 1 398 ? 51.74407  -9.54932  -37.17572 1.000 76.06331  ? 398 PRO B N   1 
ATOM   6977 C  CA  . PRO B 1 398 ? 52.87980  -8.70010  -36.78615 1.000 66.36789  ? 398 PRO B CA  1 
ATOM   6978 C  C   . PRO B 1 398 ? 54.21578  -9.12060  -37.38474 1.000 79.09608  ? 398 PRO B C   1 
ATOM   6979 O  O   . PRO B 1 398 ? 54.85813  -8.32060  -38.07242 1.000 80.07288  ? 398 PRO B O   1 
ATOM   6980 C  CB  . PRO B 1 398 ? 52.89463  -8.82631  -35.25726 1.000 68.25608  ? 398 PRO B CB  1 
ATOM   6981 C  CG  . PRO B 1 398 ? 51.48162  -9.15892  -34.89528 1.000 63.95472  ? 398 PRO B CG  1 
ATOM   6982 C  CD  . PRO B 1 398 ? 50.97550  -10.02273 -36.01188 1.000 78.38805  ? 398 PRO B CD  1 
ATOM   6983 N  N   . ARG B 1 399 ? 54.64574  -10.36214 -37.13554 1.000 81.64373  ? 399 ARG B N   1 
ATOM   6984 C  CA  . ARG B 1 399 ? 55.95867  -10.80480 -37.60410 1.000 88.65710  ? 399 ARG B CA  1 
ATOM   6985 C  C   . ARG B 1 399 ? 56.02824  -10.86037 -39.12686 1.000 91.08886  ? 399 ARG B C   1 
ATOM   6986 O  O   . ARG B 1 399 ? 57.05422  -10.49964 -39.71641 1.000 92.59585  ? 399 ARG B O   1 
ATOM   6987 C  CB  . ARG B 1 399 ? 56.30333  -12.16947 -37.00089 1.000 87.82006  ? 399 ARG B CB  1 
ATOM   6988 C  CG  . ARG B 1 399 ? 57.57766  -12.81331 -37.55275 1.000 88.42222  ? 399 ARG B CG  1 
ATOM   6989 C  CD  . ARG B 1 399 ? 58.78908  -11.88944 -37.43752 1.000 89.87440  ? 399 ARG B CD  1 
ATOM   6990 N  NE  . ARG B 1 399 ? 60.01146  -12.52431 -37.91889 1.000 91.31358  ? 399 ARG B NE  1 
ATOM   6991 C  CZ  . ARG B 1 399 ? 61.13422  -11.87525 -38.19786 1.000 96.54621  ? 399 ARG B CZ  1 
ATOM   6992 N  NH1 . ARG B 1 399 ? 61.24304  -10.56947 -38.00998 1.000 100.16169 ? 399 ARG B NH1 1 
ATOM   6993 N  NH2 . ARG B 1 399 ? 62.16852  -12.55061 -38.69091 1.000 90.01157  ? 399 ARG B NH2 1 
ATOM   6994 N  N   . PHE B 1 400 ? 54.95702  -11.31650 -39.78122 1.000 74.98264  ? 400 PHE B N   1 
ATOM   6995 C  CA  . PHE B 1 400 ? 54.96101  -11.37595 -41.24089 1.000 73.23227  ? 400 PHE B CA  1 
ATOM   6996 C  C   . PHE B 1 400 ? 55.25636  -10.00836 -41.84395 1.000 83.45298  ? 400 PHE B C   1 
ATOM   6997 O  O   . PHE B 1 400 ? 55.98574  -9.90219  -42.83733 1.000 96.48277  ? 400 PHE B O   1 
ATOM   6998 C  CB  . PHE B 1 400 ? 53.61961  -11.89440 -41.76446 1.000 81.85998  ? 400 PHE B CB  1 
ATOM   6999 C  CG  . PHE B 1 400 ? 53.34123  -13.34099 -41.44775 1.000 86.31781  ? 400 PHE B CG  1 
ATOM   7000 C  CD1 . PHE B 1 400 ? 54.23658  -14.10718 -40.71537 1.000 88.42438  ? 400 PHE B CD1 1 
ATOM   7001 C  CD2 . PHE B 1 400 ? 52.17792  -13.93701 -41.90282 1.000 75.89374  ? 400 PHE B CD2 1 
ATOM   7002 C  CE1 . PHE B 1 400 ? 53.96444  -15.43348 -40.43401 1.000 72.67174  ? 400 PHE B CE1 1 
ATOM   7003 C  CE2 . PHE B 1 400 ? 51.90238  -15.26027 -41.62723 1.000 77.28399  ? 400 PHE B CE2 1 
ATOM   7004 C  CZ  . PHE B 1 400 ? 52.79696  -16.01011 -40.89183 1.000 67.86386  ? 400 PHE B CZ  1 
ATOM   7005 N  N   . THR B 1 401 ? 54.69264  -8.95127  -41.25600 1.000 79.91748  ? 401 THR B N   1 
ATOM   7006 C  CA  . THR B 1 401 ? 54.89163  -7.60246  -41.77853 1.000 74.30891  ? 401 THR B CA  1 
ATOM   7007 C  C   . THR B 1 401 ? 56.35552  -7.18213  -41.69592 1.000 80.58131  ? 401 THR B C   1 
ATOM   7008 O  O   . THR B 1 401 ? 56.92351  -6.67431  -42.67028 1.000 89.68700  ? 401 THR B O   1 
ATOM   7009 C  CB  . THR B 1 401 ? 54.00645  -6.61335  -41.01627 1.000 72.82558  ? 401 THR B CB  1 
ATOM   7010 O  OG1 . THR B 1 401 ? 52.64218  -7.04621  -41.07555 1.000 73.37457  ? 401 THR B OG1 1 
ATOM   7011 C  CG2 . THR B 1 401 ? 54.11074  -5.22351  -41.61837 1.000 67.02409  ? 401 THR B CG2 1 
ATOM   7012 N  N   . GLU B 1 402 ? 56.98185  -7.38296  -40.53264 1.000 83.40461  ? 402 GLU B N   1 
ATOM   7013 C  CA  . GLU B 1 402 ? 58.35211  -6.91704  -40.32807 1.000 84.39170  ? 402 GLU B CA  1 
ATOM   7014 C  C   . GLU B 1 402 ? 59.31332  -7.57054  -41.30992 1.000 95.70573  ? 402 GLU B C   1 
ATOM   7015 O  O   . GLU B 1 402 ? 60.15502  -6.89734  -41.91776 1.000 84.98599  ? 402 GLU B O   1 
ATOM   7016 C  CB  . GLU B 1 402 ? 58.80173  -7.21056  -38.89839 1.000 87.95381  ? 402 GLU B CB  1 
ATOM   7017 C  CG  . GLU B 1 402 ? 57.74222  -7.01047  -37.84526 1.000 103.12126 ? 402 GLU B CG  1 
ATOM   7018 C  CD  . GLU B 1 402 ? 58.18050  -7.53742  -36.49814 1.000 95.94988  ? 402 GLU B CD  1 
ATOM   7019 O  OE1 . GLU B 1 402 ? 59.23316  -8.20933  -36.43451 1.000 95.10457  ? 402 GLU B OE1 1 
ATOM   7020 O  OE2 . GLU B 1 402 ? 57.47142  -7.27948  -35.50629 1.000 95.45634  ? 402 GLU B OE2 1 
ATOM   7021 N  N   . LEU B 1 403 ? 59.20874  -8.89050  -41.46623 1.000 101.26139 ? 403 LEU B N   1 
ATOM   7022 C  CA  . LEU B 1 403 ? 60.14013  -9.61280  -42.32461 1.000 87.16372  ? 403 LEU B CA  1 
ATOM   7023 C  C   . LEU B 1 403 ? 60.07119  -9.10429  -43.75856 1.000 83.51935  ? 403 LEU B C   1 
ATOM   7024 O  O   . LEU B 1 403 ? 61.10545  -8.93259  -44.41420 1.000 93.62010  ? 403 LEU B O   1 
ATOM   7025 C  CB  . LEU B 1 403 ? 59.84505  -11.11162 -42.25999 1.000 76.50230  ? 403 LEU B CB  1 
ATOM   7026 C  CG  . LEU B 1 403 ? 60.89415  -12.06895 -42.82525 1.000 84.67566  ? 403 LEU B CG  1 
ATOM   7027 C  CD1 . LEU B 1 403 ? 62.19923  -11.91626 -42.06703 1.000 81.32219  ? 403 LEU B CD1 1 
ATOM   7028 C  CD2 . LEU B 1 403 ? 60.39956  -13.50276 -42.75210 1.000 77.07194  ? 403 LEU B CD2 1 
ATOM   7029 N  N   . ALA B 1 404 ? 58.86141  -8.84700  -44.25932 1.000 83.20091  ? 404 ALA B N   1 
ATOM   7030 C  CA  . ALA B 1 404 ? 58.71931  -8.31063  -45.60895 1.000 83.10756  ? 404 ALA B CA  1 
ATOM   7031 C  C   . ALA B 1 404 ? 59.34970  -6.92839  -45.72942 1.000 81.63851  ? 404 ALA B C   1 
ATOM   7032 O  O   . ALA B 1 404 ? 59.87542  -6.56947  -46.78983 1.000 84.30850  ? 404 ALA B O   1 
ATOM   7033 C  CB  . ALA B 1 404 ? 57.24334  -8.26702  -46.00185 1.000 69.07520  ? 404 ALA B CB  1 
ATOM   7034 N  N   . LYS B 1 405 ? 59.29868  -6.13313  -44.65796 1.000 80.45850  ? 405 LYS B N   1 
ATOM   7035 C  CA  . LYS B 1 405 ? 59.89843  -4.80213  -44.69858 1.000 82.70266  ? 405 LYS B CA  1 
ATOM   7036 C  C   . LYS B 1 405 ? 61.41867  -4.88088  -44.79840 1.000 88.86896  ? 405 LYS B C   1 
ATOM   7037 O  O   . LYS B 1 405 ? 62.03262  -4.16782  -45.60098 1.000 92.07546  ? 405 LYS B O   1 
ATOM   7038 C  CB  . LYS B 1 405 ? 59.47757  -3.99649  -43.46928 1.000 76.09246  ? 405 LYS B CB  1 
ATOM   7039 C  CG  . LYS B 1 405 ? 59.67111  -2.49698  -43.62592 1.000 67.63927  ? 405 LYS B CG  1 
ATOM   7040 C  CD  . LYS B 1 405 ? 58.94995  -1.72769  -42.53297 1.000 61.58802  ? 405 LYS B CD  1 
ATOM   7041 C  CE  . LYS B 1 405 ? 58.91654  -0.23852  -42.83612 1.000 78.77892  ? 405 LYS B CE  1 
ATOM   7042 N  NZ  . LYS B 1 405 ? 57.99267  0.48588   -41.91973 1.000 77.40401  ? 405 LYS B NZ  1 
ATOM   7043 N  N   . GLU B 1 406 ? 62.04522  -5.73552  -43.98346 1.000 82.24890  ? 406 GLU B N   1 
ATOM   7044 C  CA  . GLU B 1 406 ? 63.49221  -5.90995  -44.07109 1.000 79.84010  ? 406 GLU B CA  1 
ATOM   7045 C  C   . GLU B 1 406 ? 63.89618  -6.40643  -45.45170 1.000 89.50088  ? 406 GLU B C   1 
ATOM   7046 O  O   . GLU B 1 406 ? 64.85371  -5.90746  -46.05385 1.000 95.85479  ? 406 GLU B O   1 
ATOM   7047 C  CB  . GLU B 1 406 ? 63.98566  -6.89293  -43.00869 1.000 75.16472  ? 406 GLU B CB  1 
ATOM   7048 C  CG  . GLU B 1 406 ? 63.55907  -6.61146  -41.58313 1.000 99.89376  ? 406 GLU B CG  1 
ATOM   7049 C  CD  . GLU B 1 406 ? 64.01222  -7.70848  -40.63293 1.000 109.68663 ? 406 GLU B CD  1 
ATOM   7050 O  OE1 . GLU B 1 406 ? 64.88325  -8.51089  -41.03142 1.000 98.75525  ? 406 GLU B OE1 1 
ATOM   7051 O  OE2 . GLU B 1 406 ? 63.49546  -7.77757  -39.49669 1.000 104.98987 ? 406 GLU B OE2 1 
ATOM   7052 N  N   . ASN B 1 407 ? 63.16924  -7.39681  -45.96938 1.000 89.79791  ? 407 ASN B N   1 
ATOM   7053 C  CA  . ASN B 1 407 ? 63.54095  -8.02419  -47.23078 1.000 87.02203  ? 407 ASN B CA  1 
ATOM   7054 C  C   . ASN B 1 407 ? 63.20430  -7.15777  -48.43570 1.000 93.79708  ? 407 ASN B C   1 
ATOM   7055 O  O   . ASN B 1 407 ? 63.70606  -7.42435  -49.53331 1.000 98.72768  ? 407 ASN B O   1 
ATOM   7056 C  CB  . ASN B 1 407 ? 62.85145  -9.38583  -47.35395 1.000 88.13571  ? 407 ASN B CB  1 
ATOM   7057 C  CG  . ASN B 1 407 ? 63.23513  -10.33874 -46.23519 1.000 91.03329  ? 407 ASN B CG  1 
ATOM   7058 O  OD1 . ASN B 1 407 ? 64.04785  -10.00865 -45.36990 1.000 95.97686  ? 407 ASN B OD1 1 
ATOM   7059 N  ND2 . ASN B 1 407 ? 62.64152  -11.52690 -46.24343 1.000 65.81488  ? 407 ASN B ND2 1 
ATOM   7060 N  N   . GLY B 1 408 ? 62.37341  -6.13564  -48.25808 1.000 85.60797  ? 408 GLY B N   1 
ATOM   7061 C  CA  . GLY B 1 408 ? 62.02825  -5.24499  -49.34438 1.000 77.90216  ? 408 GLY B CA  1 
ATOM   7062 C  C   . GLY B 1 408 ? 60.83553  -5.65880  -50.17250 1.000 84.45808  ? 408 GLY B C   1 
ATOM   7063 O  O   . GLY B 1 408 ? 60.67705  -5.16264  -51.29314 1.000 82.97581  ? 408 GLY B O   1 
ATOM   7064 N  N   . VAL B 1 409 ? 59.99413  -6.55108  -49.66451 1.000 76.86799  ? 409 VAL B N   1 
ATOM   7065 C  CA  . VAL B 1 409 ? 58.82693  -7.01481  -50.40621 1.000 69.12207  ? 409 VAL B CA  1 
ATOM   7066 C  C   . VAL B 1 409 ? 57.71505  -5.98271  -50.27851 1.000 68.33706  ? 409 VAL B C   1 
ATOM   7067 O  O   . VAL B 1 409 ? 57.32101  -5.61064  -49.16707 1.000 73.83316  ? 409 VAL B O   1 
ATOM   7068 C  CB  . VAL B 1 409 ? 58.37559  -8.39232  -49.89886 1.000 70.01961  ? 409 VAL B CB  1 
ATOM   7069 C  CG1 . VAL B 1 409 ? 57.40430  -9.02471  -50.87866 1.000 82.04234  ? 409 VAL B CG1 1 
ATOM   7070 C  CG2 . VAL B 1 409 ? 59.58425  -9.28924  -49.67351 1.000 71.47762  ? 409 VAL B CG2 1 
ATOM   7071 N  N   . ALA B 1 410 ? 57.20433  -5.51971  -51.41879 1.000 69.69386  ? 410 ALA B N   1 
ATOM   7072 C  CA  . ALA B 1 410 ? 56.19818  -4.47053  -51.47137 1.000 75.78640  ? 410 ALA B CA  1 
ATOM   7073 C  C   . ALA B 1 410 ? 54.82583  -5.04981  -51.79185 1.000 70.21672  ? 410 ALA B C   1 
ATOM   7074 O  O   . ALA B 1 410 ? 54.70558  -6.11946  -52.39640 1.000 66.55108  ? 410 ALA B O   1 
ATOM   7075 C  CB  . ALA B 1 410 ? 56.56411  -3.40527  -52.51399 1.000 70.57274  ? 410 ALA B CB  1 
ATOM   7076 N  N   . VAL B 1 411 ? 53.78825  -4.32221  -51.38183 1.000 70.16587  ? 411 VAL B N   1 
ATOM   7077 C  CA  . VAL B 1 411 ? 52.40127  -4.74163  -51.54176 1.000 61.74550  ? 411 VAL B CA  1 
ATOM   7078 C  C   . VAL B 1 411 ? 51.75162  -3.90437  -52.63438 1.000 64.05164  ? 411 VAL B C   1 
ATOM   7079 O  O   . VAL B 1 411 ? 51.91830  -2.67980  -52.67763 1.000 72.86726  ? 411 VAL B O   1 
ATOM   7080 C  CB  . VAL B 1 411 ? 51.61918  -4.61499  -50.22028 1.000 61.66718  ? 411 VAL B CB  1 
ATOM   7081 C  CG1 . VAL B 1 411 ? 50.26390  -5.27940  -50.34323 1.000 60.97340  ? 411 VAL B CG1 1 
ATOM   7082 C  CG2 . VAL B 1 411 ? 52.41104  -5.21457  -49.06740 1.000 57.91060  ? 411 VAL B CG2 1 
ATOM   7083 N  N   . GLU B 1 412 ? 51.01148  -4.56977  -53.51622 1.000 60.56090  ? 412 GLU B N   1 
ATOM   7084 C  CA  . GLU B 1 412 ? 50.26684  -3.90727  -54.58248 1.000 61.96414  ? 412 GLU B CA  1 
ATOM   7085 C  C   . GLU B 1 412 ? 48.84508  -3.65630  -54.09070 1.000 63.04725  ? 412 GLU B C   1 
ATOM   7086 O  O   . GLU B 1 412 ? 48.04885  -4.59284  -53.97265 1.000 58.33810  ? 412 GLU B O   1 
ATOM   7087 C  CB  . GLU B 1 412 ? 50.27132  -4.76482  -55.84422 1.000 75.76681  ? 412 GLU B CB  1 
ATOM   7088 C  CG  . GLU B 1 412 ? 51.65921  -5.14735  -56.32911 1.000 67.51535  ? 412 GLU B CG  1 
ATOM   7089 C  CD  . GLU B 1 412 ? 51.64499  -6.38187  -57.20787 1.000 69.72333  ? 412 GLU B CD  1 
ATOM   7090 O  OE1 . GLU B 1 412 ? 50.74619  -7.22854  -57.02448 1.000 63.11249  ? 412 GLU B OE1 1 
ATOM   7091 O  OE2 . GLU B 1 412 ? 52.52898  -6.50610  -58.08146 1.000 69.29454  ? 412 GLU B OE2 1 
ATOM   7092 N  N   . VAL B 1 413 ? 48.52465  -2.39671  -53.80792 1.000 57.34083  ? 413 VAL B N   1 
ATOM   7093 C  CA  . VAL B 1 413 ? 47.24147  -2.01687  -53.22556 1.000 59.58577  ? 413 VAL B CA  1 
ATOM   7094 C  C   . VAL B 1 413 ? 46.32051  -1.55448  -54.34719 1.000 54.73766  ? 413 VAL B C   1 
ATOM   7095 O  O   . VAL B 1 413 ? 46.65240  -0.62211  -55.08964 1.000 51.79406  ? 413 VAL B O   1 
ATOM   7096 C  CB  . VAL B 1 413 ? 47.41188  -0.92001  -52.16222 1.000 57.87993  ? 413 VAL B CB  1 
ATOM   7097 C  CG1 . VAL B 1 413 ? 46.16447  -0.81813  -51.29497 1.000 40.62674  ? 413 VAL B CG1 1 
ATOM   7098 C  CG2 . VAL B 1 413 ? 48.65145  -1.18333  -51.31665 1.000 41.89671  ? 413 VAL B CG2 1 
ATOM   7099 N  N   . ASN B 1 414 ? 45.16411  -2.20366  -54.46971 1.000 56.74585  ? 414 ASN B N   1 
ATOM   7100 C  CA  . ASN B 1 414 ? 44.16585  -1.87005  -55.48804 1.000 66.52621  ? 414 ASN B CA  1 
ATOM   7101 C  C   . ASN B 1 414 ? 42.85523  -1.49653  -54.80690 1.000 64.26385  ? 414 ASN B C   1 
ATOM   7102 O  O   . ASN B 1 414 ? 42.07537  -2.38736  -54.42392 1.000 75.36004  ? 414 ASN B O   1 
ATOM   7103 C  CB  . ASN B 1 414 ? 43.96208  -3.04005  -56.44894 1.000 70.57004  ? 414 ASN B CB  1 
ATOM   7104 C  CG  . ASN B 1 414 ? 45.27159  -3.67820  -56.87269 1.000 71.98173  ? 414 ASN B CG  1 
ATOM   7105 O  OD1 . ASN B 1 414 ? 46.06279  -3.07891  -57.59963 1.000 70.44055  ? 414 ASN B OD1 1 
ATOM   7106 N  ND2 . ASN B 1 414 ? 45.50690  -4.90192  -56.41612 1.000 74.23140  ? 414 ASN B ND2 1 
ATOM   7107 N  N   . PRO B 1 415 ? 42.56571  -0.19990  -54.63092 1.000 72.18152  ? 415 PRO B N   1 
ATOM   7108 C  CA  . PRO B 1 415 ? 41.40054  0.20566   -53.82755 1.000 63.24363  ? 415 PRO B CA  1 
ATOM   7109 C  C   . PRO B 1 415 ? 40.05455  -0.18534  -54.42170 1.000 64.67423  ? 415 PRO B C   1 
ATOM   7110 O  O   . PRO B 1 415 ? 39.23953  -0.82146  -53.74703 1.000 61.32944  ? 415 PRO B O   1 
ATOM   7111 C  CB  . PRO B 1 415 ? 41.54211  1.73350   -53.75337 1.000 49.89961  ? 415 PRO B CB  1 
ATOM   7112 C  CG  . PRO B 1 415 ? 42.97409  2.01225   -54.08721 1.000 54.70141  ? 415 PRO B CG  1 
ATOM   7113 C  CD  . PRO B 1 415 ? 43.36710  0.95459   -55.06535 1.000 68.62236  ? 415 PRO B CD  1 
ATOM   7114 N  N   . ILE B 1 416 ? 39.80758  0.19100   -55.67836 1.000 75.02738  ? 416 ILE B N   1 
ATOM   7115 C  CA  . ILE B 1 416 ? 38.49360  -0.03435  -56.27521 1.000 71.37764  ? 416 ILE B CA  1 
ATOM   7116 C  C   . ILE B 1 416 ? 38.21108  -1.52506  -56.42502 1.000 69.36549  ? 416 ILE B C   1 
ATOM   7117 O  O   . ILE B 1 416 ? 37.05832  -1.96145  -56.29836 1.000 65.45651  ? 416 ILE B O   1 
ATOM   7118 C  CB  . ILE B 1 416 ? 38.38337  0.70718   -57.62040 1.000 67.22124  ? 416 ILE B CB  1 
ATOM   7119 C  CG1 . ILE B 1 416 ? 38.70185  2.19075   -57.43264 1.000 71.83399  ? 416 ILE B CG1 1 
ATOM   7120 C  CG2 . ILE B 1 416 ? 36.98968  0.55489   -58.19995 1.000 57.01703  ? 416 ILE B CG2 1 
ATOM   7121 C  CD1 . ILE B 1 416 ? 38.42189  3.03725   -58.65401 1.000 67.19889  ? 416 ILE B CD1 1 
ATOM   7122 N  N   . SER B 1 417 ? 39.24103  -2.32770  -56.70403 1.000 71.47292  ? 417 SER B N   1 
ATOM   7123 C  CA  . SER B 1 417 ? 39.06531  -3.77737  -56.75790 1.000 67.87724  ? 417 SER B CA  1 
ATOM   7124 C  C   . SER B 1 417 ? 38.56315  -4.31805  -55.42804 1.000 66.83164  ? 417 SER B C   1 
ATOM   7125 O  O   . SER B 1 417 ? 37.62355  -5.12010  -55.38290 1.000 58.54094  ? 417 SER B O   1 
ATOM   7126 C  CB  . SER B 1 417 ? 40.38576  -4.45327  -57.12849 1.000 65.02370  ? 417 SER B CB  1 
ATOM   7127 O  OG  . SER B 1 417 ? 40.32245  -5.84955  -56.90175 1.000 70.96116  ? 417 SER B OG  1 
ATOM   7128 N  N   . ASN B 1 418 ? 39.18799  -3.88987  -54.33143 1.000 61.07558  ? 418 ASN B N   1 
ATOM   7129 C  CA  . ASN B 1 418 ? 38.84487  -4.41467  -53.01890 1.000 49.01951  ? 418 ASN B CA  1 
ATOM   7130 C  C   . ASN B 1 418 ? 37.45649  -3.98980  -52.55964 1.000 53.41640  ? 418 ASN B C   1 
ATOM   7131 O  O   . ASN B 1 418 ? 36.89588  -4.62937  -51.66332 1.000 52.68084  ? 418 ASN B O   1 
ATOM   7132 C  CB  . ASN B 1 418 ? 39.89497  -3.97985  -51.99823 1.000 47.40816  ? 418 ASN B CB  1 
ATOM   7133 C  CG  . ASN B 1 418 ? 41.26703  -4.56200  -52.28723 1.000 57.02019  ? 418 ASN B CG  1 
ATOM   7134 O  OD1 . ASN B 1 418 ? 41.48147  -5.20083  -53.31817 1.000 62.56494  ? 418 ASN B OD1 1 
ATOM   7135 N  ND2 . ASN B 1 418 ? 42.20436  -4.34168  -51.37610 1.000 53.53995  ? 418 ASN B ND2 1 
ATOM   7136 N  N   . GLN B 1 419 ? 36.88846  -2.93108  -53.13920 1.000 50.28870  ? 419 GLN B N   1 
ATOM   7137 C  CA  . GLN B 1 419 ? 35.54096  -2.53227  -52.74507 1.000 59.48728  ? 419 GLN B CA  1 
ATOM   7138 C  C   . GLN B 1 419 ? 34.48429  -3.30483  -53.52358 1.000 66.20032  ? 419 GLN B C   1 
ATOM   7139 O  O   . GLN B 1 419 ? 33.56002  -3.87458  -52.93318 1.000 69.86408  ? 419 GLN B O   1 
ATOM   7140 C  CB  . GLN B 1 419 ? 35.33743  -1.02816  -52.94207 1.000 41.07241  ? 419 GLN B CB  1 
ATOM   7141 C  CG  . GLN B 1 419 ? 33.92559  -0.57237  -52.58196 1.000 43.69100  ? 419 GLN B CG  1 
ATOM   7142 C  CD  . GLN B 1 419 ? 33.62851  0.85226   -53.00676 1.000 56.31433  ? 419 GLN B CD  1 
ATOM   7143 O  OE1 . GLN B 1 419 ? 33.59220  1.16523   -54.19709 1.000 47.68522  ? 419 GLN B OE1 1 
ATOM   7144 N  NE2 . GLN B 1 419 ? 33.40784  1.72414   -52.03081 1.000 72.47843  ? 419 GLN B NE2 1 
ATOM   7145 N  N   . ILE B 1 420 ? 34.60630  -3.32935  -54.85196 1.000 59.66843  ? 420 ILE B N   1 
ATOM   7146 C  CA  . ILE B 1 420 ? 33.59751  -3.97810  -55.68460 1.000 58.39284  ? 420 ILE B CA  1 
ATOM   7147 C  C   . ILE B 1 420 ? 33.54432  -5.47403  -55.39790 1.000 64.94254  ? 420 ILE B C   1 
ATOM   7148 O  O   . ILE B 1 420 ? 32.46156  -6.06283  -55.29722 1.000 64.09859  ? 420 ILE B O   1 
ATOM   7149 C  CB  . ILE B 1 420 ? 33.87180  -3.68706  -57.17134 1.000 51.52199  ? 420 ILE B CB  1 
ATOM   7150 C  CG1 . ILE B 1 420 ? 33.96782  -2.17685  -57.39221 1.000 45.28362  ? 420 ILE B CG1 1 
ATOM   7151 C  CG2 . ILE B 1 420 ? 32.78088  -4.28199  -58.04649 1.000 41.58452  ? 420 ILE B CG2 1 
ATOM   7152 C  CD1 . ILE B 1 420 ? 33.95430  -1.76932  -58.83542 1.000 61.85376  ? 420 ILE B CD1 1 
ATOM   7153 N  N   . LEU B 1 421 ? 34.70521  -6.11092  -55.25409 1.000 62.77439  ? 421 LEU B N   1 
ATOM   7154 C  CA  . LEU B 1 421 ? 34.76490  -7.54260  -54.98810 1.000 57.44508  ? 421 LEU B CA  1 
ATOM   7155 C  C   . LEU B 1 421 ? 34.58354  -7.88672  -53.51056 1.000 56.10728  ? 421 LEU B C   1 
ATOM   7156 O  O   . LEU B 1 421 ? 34.91119  -9.00640  -53.10631 1.000 66.39941  ? 421 LEU B O   1 
ATOM   7157 C  CB  . LEU B 1 421 ? 36.08007  -8.12039  -55.51883 1.000 59.11867  ? 421 LEU B CB  1 
ATOM   7158 C  CG  . LEU B 1 421 ? 36.16230  -8.13290  -57.04853 1.000 47.90686  ? 421 LEU B CG  1 
ATOM   7159 C  CD1 . LEU B 1 421 ? 37.46546  -8.74320  -57.53650 1.000 42.15229  ? 421 LEU B CD1 1 
ATOM   7160 C  CD2 . LEU B 1 421 ? 34.96839  -8.87098  -57.64148 1.000 47.09574  ? 421 LEU B CD2 1 
ATOM   7161 N  N   . GLY B 1 422 ? 34.08675  -6.95413  -52.70457 1.000 63.47751  ? 422 GLY B N   1 
ATOM   7162 C  CA  . GLY B 1 422 ? 33.56638  -7.28137  -51.38941 1.000 66.03779  ? 422 GLY B CA  1 
ATOM   7163 C  C   . GLY B 1 422 ? 34.56003  -7.61922  -50.29803 1.000 56.95324  ? 422 GLY B C   1 
ATOM   7164 O  O   . GLY B 1 422 ? 34.34060  -8.57612  -49.54413 1.000 61.97889  ? 422 GLY B O   1 
ATOM   7165 N  N   . LEU B 1 423 ? 35.64991  -6.86048  -50.18326 1.000 66.36000  ? 423 LEU B N   1 
ATOM   7166 C  CA  . LEU B 1 423 ? 36.48227  -6.90792  -48.98791 1.000 59.16088  ? 423 LEU B CA  1 
ATOM   7167 C  C   . LEU B 1 423 ? 36.20490  -5.75460  -48.03616 1.000 68.84472  ? 423 LEU B C   1 
ATOM   7168 O  O   . LEU B 1 423 ? 36.50487  -5.86859  -46.84336 1.000 59.49718  ? 423 LEU B O   1 
ATOM   7169 C  CB  . LEU B 1 423 ? 37.96985  -6.89084  -49.35878 1.000 55.89693  ? 423 LEU B CB  1 
ATOM   7170 C  CG  . LEU B 1 423 ? 38.51666  -8.05993  -50.17392 1.000 60.67806  ? 423 LEU B CG  1 
ATOM   7171 C  CD1 . LEU B 1 423 ? 39.99889  -7.85174  -50.43314 1.000 62.81087  ? 423 LEU B CD1 1 
ATOM   7172 C  CD2 . LEU B 1 423 ? 38.26802  -9.37921  -49.46070 1.000 66.18443  ? 423 LEU B CD2 1 
ATOM   7173 N  N   . VAL B 1 424 ? 35.63608  -4.65927  -48.53807 1.000 68.30258  ? 424 VAL B N   1 
ATOM   7174 C  CA  . VAL B 1 424 ? 35.34933  -3.48038  -47.73314 1.000 51.10886  ? 424 VAL B CA  1 
ATOM   7175 C  C   . VAL B 1 424 ? 34.26888  -2.69483  -48.45963 1.000 51.54401  ? 424 VAL B C   1 
ATOM   7176 O  O   . VAL B 1 424 ? 34.16858  -2.74280  -49.68735 1.000 61.09550  ? 424 VAL B O   1 
ATOM   7177 C  CB  . VAL B 1 424 ? 36.62895  -2.63518  -47.50117 1.000 60.65430  ? 424 VAL B CB  1 
ATOM   7178 C  CG1 . VAL B 1 424 ? 37.08644  -1.98085  -48.79956 1.000 51.84218  ? 424 VAL B CG1 1 
ATOM   7179 C  CG2 . VAL B 1 424 ? 36.40708  -1.59683  -46.41229 1.000 65.48767  ? 424 VAL B CG2 1 
ATOM   7180 N  N   . ARG B 1 425 ? 33.44030  -1.98605  -47.69615 1.000 55.20775  ? 425 ARG B N   1 
ATOM   7181 C  CA  . ARG B 1 425 ? 32.37729  -1.16962  -48.27099 1.000 57.16642  ? 425 ARG B CA  1 
ATOM   7182 C  C   . ARG B 1 425 ? 32.73376  0.31136   -48.26855 1.000 67.47077  ? 425 ARG B C   1 
ATOM   7183 O  O   . ARG B 1 425 ? 32.68149  0.97029   -49.31113 1.000 67.61882  ? 425 ARG B O   1 
ATOM   7184 C  CB  . ARG B 1 425 ? 31.06845  -1.40301  -47.51028 1.000 59.49850  ? 425 ARG B CB  1 
ATOM   7185 C  CG  . ARG B 1 425 ? 29.81105  -1.14264  -48.32248 1.000 64.90306  ? 425 ARG B CG  1 
ATOM   7186 C  CD  . ARG B 1 425 ? 28.58293  -1.55178  -47.53286 1.000 81.62881  ? 425 ARG B CD  1 
ATOM   7187 N  NE  . ARG B 1 425 ? 27.53096  -2.10759  -48.37595 1.000 88.77030  ? 425 ARG B NE  1 
ATOM   7188 C  CZ  . ARG B 1 425 ? 26.34435  -1.54762  -48.56572 1.000 89.70531  ? 425 ARG B CZ  1 
ATOM   7189 N  NH1 . ARG B 1 425 ? 26.01683  -0.40633  -47.98254 1.000 95.97496  ? 425 ARG B NH1 1 
ATOM   7190 N  NH2 . ARG B 1 425 ? 25.46045  -2.15295  -49.35391 1.000 81.82780  ? 425 ARG B NH2 1 
ATOM   7191 N  N   . ASP B 1 426 ? 33.10148  0.84263   -47.10812 1.000 76.44924  ? 426 ASP B N   1 
ATOM   7192 C  CA  . ASP B 1 426 ? 33.63133  2.19556   -46.99003 1.000 62.84296  ? 426 ASP B CA  1 
ATOM   7193 C  C   . ASP B 1 426 ? 35.14704  2.09812   -47.13982 1.000 64.86348  ? 426 ASP B C   1 
ATOM   7194 O  O   . ASP B 1 426 ? 35.82230  1.49744   -46.29781 1.000 73.30773  ? 426 ASP B O   1 
ATOM   7195 C  CB  . ASP B 1 426 ? 33.21662  2.81072   -45.65353 1.000 70.00281  ? 426 ASP B CB  1 
ATOM   7196 C  CG  . ASP B 1 426 ? 33.53633  4.29175   -45.56023 1.000 73.62171  ? 426 ASP B CG  1 
ATOM   7197 O  OD1 . ASP B 1 426 ? 34.66354  4.69854   -45.91530 1.000 77.96790  ? 426 ASP B OD1 1 
ATOM   7198 O  OD2 . ASP B 1 426 ? 32.64505  5.05488   -45.13777 1.000 75.16900  ? 426 ASP B OD2 1 
ATOM   7199 N  N   . VAL B 1 427 ? 35.67952  2.67286   -48.22380 1.000 62.06432  ? 427 VAL B N   1 
ATOM   7200 C  CA  . VAL B 1 427 ? 37.09602  2.51683   -48.55185 1.000 61.23712  ? 427 VAL B CA  1 
ATOM   7201 C  C   . VAL B 1 427 ? 37.99960  3.03364   -47.43992 1.000 61.18988  ? 427 VAL B C   1 
ATOM   7202 O  O   . VAL B 1 427 ? 39.14305  2.58420   -47.31255 1.000 57.62021  ? 427 VAL B O   1 
ATOM   7203 C  CB  . VAL B 1 427 ? 37.41362  3.21232   -49.89384 1.000 57.71638  ? 427 VAL B CB  1 
ATOM   7204 C  CG1 . VAL B 1 427 ? 38.80131  2.82316   -50.37715 1.000 37.03711  ? 427 VAL B CG1 1 
ATOM   7205 C  CG2 . VAL B 1 427 ? 36.36721  2.85848   -50.94158 1.000 61.26488  ? 427 VAL B CG2 1 
ATOM   7206 N  N   . ARG B 1 428 ? 37.50572  3.95257   -46.60840 1.000 67.54885  ? 428 ARG B N   1 
ATOM   7207 C  CA  . ARG B 1 428 ? 38.29372  4.45989   -45.49152 1.000 60.44212  ? 428 ARG B CA  1 
ATOM   7208 C  C   . ARG B 1 428 ? 38.59965  3.39028   -44.45013 1.000 58.43054  ? 428 ARG B C   1 
ATOM   7209 O  O   . ARG B 1 428 ? 39.45736  3.61701   -43.59057 1.000 76.09975  ? 428 ARG B O   1 
ATOM   7210 C  CB  . ARG B 1 428 ? 37.57130  5.63562   -44.83717 1.000 58.22377  ? 428 ARG B CB  1 
ATOM   7211 C  CG  . ARG B 1 428 ? 37.48117  6.86625   -45.72255 1.000 50.05783  ? 428 ARG B CG  1 
ATOM   7212 C  CD  . ARG B 1 428 ? 36.64894  7.94734   -45.06396 1.000 45.45357  ? 428 ARG B CD  1 
ATOM   7213 N  NE  . ARG B 1 428 ? 35.22285  7.69840   -45.22950 1.000 52.53960  ? 428 ARG B NE  1 
ATOM   7214 C  CZ  . ARG B 1 428 ? 34.28450  8.13600   -44.40141 1.000 65.46659  ? 428 ARG B CZ  1 
ATOM   7215 N  NH1 . ARG B 1 428 ? 34.58810  8.83552   -43.32026 1.000 65.76541  ? 428 ARG B NH1 1 
ATOM   7216 N  NH2 . ARG B 1 428 ? 33.01005  7.85812   -44.65992 1.000 73.85288  ? 428 ARG B NH2 1 
ATOM   7217 N  N   . ASN B 1 429 ? 37.92210  2.24304   -44.50234 1.000 59.14898  ? 429 ASN B N   1 
ATOM   7218 C  CA  . ASN B 1 429 ? 38.20607  1.10936   -43.63454 1.000 59.87653  ? 429 ASN B CA  1 
ATOM   7219 C  C   . ASN B 1 429 ? 39.18905  0.12749   -44.26191 1.000 62.97392  ? 429 ASN B C   1 
ATOM   7220 O  O   . ASN B 1 429 ? 39.28390  -1.01680  -43.80427 1.000 69.41149  ? 429 ASN B O   1 
ATOM   7221 C  CB  . ASN B 1 429 ? 36.90936  0.38240   -43.26592 1.000 60.47498  ? 429 ASN B CB  1 
ATOM   7222 C  CG  . ASN B 1 429 ? 36.07644  1.14573   -42.25178 1.000 72.50123  ? 429 ASN B CG  1 
ATOM   7223 O  OD1 . ASN B 1 429 ? 36.59642  1.63755   -41.24992 1.000 77.33201  ? 429 ASN B OD1 1 
ATOM   7224 N  ND2 . ASN B 1 429 ? 34.77594  1.24781   -42.50822 1.000 66.96057  ? 429 ASN B ND2 1 
ATOM   7225 N  N   . HIS B 1 430 ? 39.90601  0.54486   -45.30355 1.000 63.04846  ? 430 HIS B N   1 
ATOM   7226 C  CA  . HIS B 1 430 ? 40.87153  -0.33107  -45.95279 1.000 54.67817  ? 430 HIS B CA  1 
ATOM   7227 C  C   . HIS B 1 430 ? 41.94080  -0.76709  -44.95897 1.000 51.80874  ? 430 HIS B C   1 
ATOM   7228 O  O   . HIS B 1 430 ? 42.37302  0.00873   -44.10299 1.000 51.68219  ? 430 HIS B O   1 
ATOM   7229 C  CB  . HIS B 1 430 ? 41.51161  0.38363   -47.14215 1.000 58.21779  ? 430 HIS B CB  1 
ATOM   7230 C  CG  . HIS B 1 430 ? 42.00470  -0.53945  -48.21252 1.000 57.91395  ? 430 HIS B CG  1 
ATOM   7231 N  ND1 . HIS B 1 430 ? 43.24841  -1.13163  -48.17302 1.000 54.02857  ? 430 HIS B ND1 1 
ATOM   7232 C  CD2 . HIS B 1 430 ? 41.42485  -0.96012  -49.36157 1.000 57.36776  ? 430 HIS B CD2 1 
ATOM   7233 C  CE1 . HIS B 1 430 ? 43.41055  -1.88329  -49.24742 1.000 64.06489  ? 430 HIS B CE1 1 
ATOM   7234 N  NE2 . HIS B 1 430 ? 42.31897  -1.79543  -49.98555 1.000 60.99988  ? 430 HIS B NE2 1 
ATOM   7235 N  N   . ALA B 1 431 ? 42.37034  -2.02023  -45.08044 1.000 56.50885  ? 431 ALA B N   1 
ATOM   7236 C  CA  . ALA B 1 431 ? 43.24269  -2.62079  -44.08127 1.000 66.59047  ? 431 ALA B CA  1 
ATOM   7237 C  C   . ALA B 1 431 ? 44.69602  -2.16797  -44.18137 1.000 70.29727  ? 431 ALA B C   1 
ATOM   7238 O  O   . ALA B 1 431 ? 45.48851  -2.50665  -43.29941 1.000 81.49785  ? 431 ALA B O   1 
ATOM   7239 C  CB  . ALA B 1 431 ? 43.17464  -4.14410  -44.18071 1.000 63.24139  ? 431 ALA B CB  1 
ATOM   7240 N  N   . LEU B 1 432 ? 45.06844  -1.42737  -45.21917 1.000 59.99672  ? 432 LEU B N   1 
ATOM   7241 C  CA  . LEU B 1 432 ? 46.45636  -1.05328  -45.44187 1.000 64.55783  ? 432 LEU B CA  1 
ATOM   7242 C  C   . LEU B 1 432 ? 46.74936  0.40263   -45.11463 1.000 63.27733  ? 432 LEU B C   1 
ATOM   7243 O  O   . LEU B 1 432 ? 47.91205  0.81770   -45.21491 1.000 59.94266  ? 432 LEU B O   1 
ATOM   7244 C  CB  . LEU B 1 432 ? 46.84924  -1.35919  -46.89071 1.000 52.01959  ? 432 LEU B CB  1 
ATOM   7245 C  CG  . LEU B 1 432 ? 46.71848  -2.83768  -47.24407 1.000 55.82338  ? 432 LEU B CG  1 
ATOM   7246 C  CD1 . LEU B 1 432 ? 47.22257  -3.11977  -48.64426 1.000 66.85567  ? 432 LEU B CD1 1 
ATOM   7247 C  CD2 . LEU B 1 432 ? 47.45796  -3.69639  -46.22611 1.000 65.56115  ? 432 LEU B CD2 1 
ATOM   7248 N  N   . VAL B 1 433 ? 45.73087  1.17729   -44.74778 1.000 67.99600  ? 433 VAL B N   1 
ATOM   7249 C  CA  . VAL B 1 433 ? 45.89075  2.58024   -44.37151 1.000 58.03462  ? 433 VAL B CA  1 
ATOM   7250 C  C   . VAL B 1 433 ? 46.91847  2.72313   -43.25055 1.000 67.03500  ? 433 VAL B C   1 
ATOM   7251 O  O   . VAL B 1 433 ? 47.75746  3.63894   -43.31794 1.000 73.63452  ? 433 VAL B O   1 
ATOM   7252 C  CB  . VAL B 1 433 ? 44.54437  3.21101   -43.97331 1.000 43.85131  ? 433 VAL B CB  1 
ATOM   7253 C  CG1 . VAL B 1 433 ? 44.74234  4.65844   -43.53275 1.000 64.68749  ? 433 VAL B CG1 1 
ATOM   7254 C  CG2 . VAL B 1 433 ? 43.55118  3.15197   -45.11630 1.000 41.33071  ? 433 VAL B CG2 1 
ATOM   7255 N  N   . PRO B 1 434 ? 46.88607  1.88773   -42.19860 1.000 58.93648  ? 434 PRO B N   1 
ATOM   7256 C  CA  . PRO B 1 434 ? 47.95510  1.98123   -41.19049 1.000 67.51057  ? 434 PRO B CA  1 
ATOM   7257 C  C   . PRO B 1 434 ? 49.35177  1.76906   -41.74953 1.000 69.09818  ? 434 PRO B C   1 
ATOM   7258 O  O   . PRO B 1 434 ? 50.28322  2.47894   -41.34899 1.000 69.06202  ? 434 PRO B O   1 
ATOM   7259 C  CB  . PRO B 1 434 ? 47.57868  0.88842   -40.19039 1.000 67.31944  ? 434 PRO B CB  1 
ATOM   7260 C  CG  . PRO B 1 434 ? 46.12590  0.75383   -40.32923 1.000 69.14826  ? 434 PRO B CG  1 
ATOM   7261 C  CD  . PRO B 1 434 ? 45.84250  0.93344   -41.78018 1.000 60.57302  ? 434 PRO B CD  1 
ATOM   7262 N  N   . LEU B 1 435 ? 49.52505  0.80946   -42.66292 1.000 59.23778  ? 435 LEU B N   1 
ATOM   7263 C  CA  . LEU B 1 435 ? 50.85390  0.53471   -43.20200 1.000 58.34136  ? 435 LEU B CA  1 
ATOM   7264 C  C   . LEU B 1 435 ? 51.36836  1.70701   -44.02291 1.000 69.36733  ? 435 LEU B C   1 
ATOM   7265 O  O   . LEU B 1 435 ? 52.56538  2.02001   -43.98955 1.000 76.64663  ? 435 LEU B O   1 
ATOM   7266 C  CB  . LEU B 1 435 ? 50.83574  -0.74092  -44.04357 1.000 77.77289  ? 435 LEU B CB  1 
ATOM   7267 C  CG  . LEU B 1 435 ? 50.67490  -2.05783  -43.28167 1.000 73.37913  ? 435 LEU B CG  1 
ATOM   7268 C  CD1 . LEU B 1 435 ? 50.53884  -3.21949  -44.25106 1.000 60.77858  ? 435 LEU B CD1 1 
ATOM   7269 C  CD2 . LEU B 1 435 ? 51.84469  -2.27993  -42.33005 1.000 57.84773  ? 435 LEU B CD2 1 
ATOM   7270 N  N   . ILE B 1 436 ? 50.47758  2.36216   -44.76996 1.000 69.32015  ? 436 ILE B N   1 
ATOM   7271 C  CA  . ILE B 1 436 ? 50.85744  3.55081   -45.52625 1.000 67.91036  ? 436 ILE B CA  1 
ATOM   7272 C  C   . ILE B 1 436 ? 51.39043  4.63295   -44.59810 1.000 68.05695  ? 436 ILE B C   1 
ATOM   7273 O  O   . ILE B 1 436 ? 52.29924  5.38676   -44.96648 1.000 74.22889  ? 436 ILE B O   1 
ATOM   7274 C  CB  . ILE B 1 436 ? 49.65465  4.05687   -46.34770 1.000 63.73956  ? 436 ILE B CB  1 
ATOM   7275 C  CG1 . ILE B 1 436 ? 49.12062  2.95043   -47.25710 1.000 57.97085  ? 436 ILE B CG1 1 
ATOM   7276 C  CG2 . ILE B 1 436 ? 50.04260  5.27551   -47.16156 1.000 61.91230  ? 436 ILE B CG2 1 
ATOM   7277 C  CD1 . ILE B 1 436 ? 47.96913  3.38544   -48.13466 1.000 65.30892  ? 436 ILE B CD1 1 
ATOM   7278 N  N   . ALA B 1 437 ? 50.85310  4.71814   -43.38118 1.000 69.38246  ? 437 ALA B N   1 
ATOM   7279 C  CA  . ALA B 1 437 ? 51.21723  5.76004   -42.43048 1.000 80.42878  ? 437 ALA B CA  1 
ATOM   7280 C  C   . ALA B 1 437 ? 52.53971  5.49884   -41.72057 1.000 81.94233  ? 437 ALA B C   1 
ATOM   7281 O  O   . ALA B 1 437 ? 52.96363  6.33925   -40.91985 1.000 78.70845  ? 437 ALA B O   1 
ATOM   7282 C  CB  . ALA B 1 437 ? 50.10516  5.93078   -41.39180 1.000 73.60468  ? 437 ALA B CB  1 
ATOM   7283 N  N   . ASP B 1 438 ? 53.19758  4.37094   -41.97966 1.000 71.31248  ? 438 ASP B N   1 
ATOM   7284 C  CA  . ASP B 1 438 ? 54.49428  4.07068   -41.38106 1.000 69.63409  ? 438 ASP B CA  1 
ATOM   7285 C  C   . ASP B 1 438 ? 55.51936  3.73625   -42.45656 1.000 76.04135  ? 438 ASP B C   1 
ATOM   7286 O  O   . ASP B 1 438 ? 56.41027  2.90639   -42.25386 1.000 78.70591  ? 438 ASP B O   1 
ATOM   7287 C  CB  . ASP B 1 438 ? 54.38204  2.93478   -40.36621 1.000 74.52477  ? 438 ASP B CB  1 
ATOM   7288 C  CG  . ASP B 1 438 ? 55.48174  2.97780   -39.31986 1.000 96.62110  ? 438 ASP B CG  1 
ATOM   7289 O  OD1 . ASP B 1 438 ? 56.24087  3.97076   -39.29412 1.000 103.52126 ? 438 ASP B OD1 1 
ATOM   7290 O  OD2 . ASP B 1 438 ? 55.58551  2.02104   -38.52348 1.000 86.48937  ? 438 ASP B OD2 1 
ATOM   7291 N  N   . ASP B 1 439 ? 55.41164  4.39837   -43.60575 1.000 76.66746  ? 439 ASP B N   1 
ATOM   7292 C  CA  . ASP B 1 439 ? 56.29854  4.21089   -44.75784 1.000 80.50753  ? 439 ASP B CA  1 
ATOM   7293 C  C   . ASP B 1 439 ? 56.55986  2.73236   -45.03807 1.000 88.93457  ? 439 ASP B C   1 
ATOM   7294 O  O   . ASP B 1 439 ? 57.69257  2.25120   -45.02026 1.000 87.69178  ? 439 ASP B O   1 
ATOM   7295 C  CB  . ASP B 1 439 ? 57.61262  4.96486   -44.57951 1.000 86.63294  ? 439 ASP B CB  1 
ATOM   7296 C  CG  . ASP B 1 439 ? 58.31668  5.21669   -45.90234 1.000 103.43433 ? 439 ASP B CG  1 
ATOM   7297 O  OD1 . ASP B 1 439 ? 57.80770  6.03498   -46.69926 1.000 100.69118 ? 439 ASP B OD1 1 
ATOM   7298 O  OD2 . ASP B 1 439 ? 59.36854  4.59052   -46.15297 1.000 109.04897 ? 439 ASP B OD2 1 
ATOM   7299 N  N   . TYR B 1 440 ? 55.47444  2.01185   -45.29219 1.000 86.92783  ? 440 TYR B N   1 
ATOM   7300 C  CA  . TYR B 1 440 ? 55.65519  0.63716   -45.73501 1.000 72.56525  ? 440 TYR B CA  1 
ATOM   7301 C  C   . TYR B 1 440 ? 55.83468  0.60606   -47.24976 1.000 79.21535  ? 440 TYR B C   1 
ATOM   7302 O  O   . TYR B 1 440 ? 55.17051  1.36210   -47.96562 1.000 81.28592  ? 440 TYR B O   1 
ATOM   7303 C  CB  . TYR B 1 440 ? 54.45587  -0.21553  -45.34231 1.000 72.87863  ? 440 TYR B CB  1 
ATOM   7304 C  CG  . TYR B 1 440 ? 54.72755  -1.69827  -45.35844 1.000 78.19698  ? 440 TYR B CG  1 
ATOM   7305 C  CD1 . TYR B 1 440 ? 55.38618  -2.31165  -44.30225 1.000 76.24412  ? 440 TYR B CD1 1 
ATOM   7306 C  CD2 . TYR B 1 440 ? 54.32224  -2.48636  -46.42721 1.000 85.49569  ? 440 TYR B CD2 1 
ATOM   7307 C  CE1 . TYR B 1 440 ? 55.63700  -3.66629  -44.31034 1.000 80.10330  ? 440 TYR B CE1 1 
ATOM   7308 C  CE2 . TYR B 1 440 ? 54.56655  -3.84318  -46.44396 1.000 95.08480  ? 440 TYR B CE2 1 
ATOM   7309 C  CZ  . TYR B 1 440 ? 55.22313  -4.42805  -45.38352 1.000 90.17313  ? 440 TYR B CZ  1 
ATOM   7310 O  OH  . TYR B 1 440 ? 55.46551  -5.77978  -45.39980 1.000 84.37541  ? 440 TYR B OH  1 
ATOM   7311 N  N   . PRO B 1 441 ? 56.73503  -0.22899  -47.77427 1.000 80.04096  ? 441 PRO B N   1 
ATOM   7312 C  CA  . PRO B 1 441 ? 56.89022  -0.30240  -49.23364 1.000 69.26142  ? 441 PRO B CA  1 
ATOM   7313 C  C   . PRO B 1 441 ? 55.60751  -0.76082  -49.90787 1.000 71.45146  ? 441 PRO B C   1 
ATOM   7314 O  O   . PRO B 1 441 ? 55.19673  -1.91443  -49.75191 1.000 74.49724  ? 441 PRO B O   1 
ATOM   7315 C  CB  . PRO B 1 441 ? 58.02982  -1.31532  -49.41856 1.000 77.99286  ? 441 PRO B CB  1 
ATOM   7316 C  CG  . PRO B 1 441 ? 58.06144  -2.10079  -48.13983 1.000 71.41326  ? 441 PRO B CG  1 
ATOM   7317 C  CD  . PRO B 1 441 ? 57.65593  -1.13653  -47.06897 1.000 75.91004  ? 441 PRO B CD  1 
ATOM   7318 N  N   . ILE B 1 442 ? 54.96380  0.13729   -50.65420 1.000 66.64325  ? 442 ILE B N   1 
ATOM   7319 C  CA  . ILE B 1 442 ? 53.69619  -0.15089  -51.31328 1.000 65.92211  ? 442 ILE B CA  1 
ATOM   7320 C  C   . ILE B 1 442 ? 53.68012  0.52807   -52.67520 1.000 60.33291  ? 442 ILE B C   1 
ATOM   7321 O  O   . ILE B 1 442 ? 54.32749  1.55774   -52.88830 1.000 54.42127  ? 442 ILE B O   1 
ATOM   7322 C  CB  . ILE B 1 442 ? 52.46953  0.31562   -50.49063 1.000 53.96540  ? 442 ILE B CB  1 
ATOM   7323 C  CG1 . ILE B 1 442 ? 52.48723  1.83434   -50.32083 1.000 70.47649  ? 442 ILE B CG1 1 
ATOM   7324 C  CG2 . ILE B 1 442 ? 52.41332  -0.37311  -49.13304 1.000 53.81159  ? 442 ILE B CG2 1 
ATOM   7325 C  CD1 . ILE B 1 442 ? 51.11192  2.44054   -50.18671 1.000 79.70134  ? 442 ILE B CD1 1 
ATOM   7326 N  N   . VAL B 1 443 ? 52.93084  -0.06638  -53.60360 1.000 64.59880  ? 443 VAL B N   1 
ATOM   7327 C  CA  . VAL B 1 443 ? 52.63313  0.53244   -54.89590 1.000 66.09048  ? 443 VAL B CA  1 
ATOM   7328 C  C   . VAL B 1 443 ? 51.13031  0.42179   -55.11692 1.000 72.61168  ? 443 VAL B C   1 
ATOM   7329 O  O   . VAL B 1 443 ? 50.43909  -0.36131  -54.46371 1.000 69.84323  ? 443 VAL B O   1 
ATOM   7330 C  CB  . VAL B 1 443 ? 53.40684  -0.12877  -56.05840 1.000 63.45069  ? 443 VAL B CB  1 
ATOM   7331 C  CG1 . VAL B 1 443 ? 54.89860  -0.18847  -55.75058 1.000 59.75637  ? 443 VAL B CG1 1 
ATOM   7332 C  CG2 . VAL B 1 443 ? 52.85873  -1.51370  -56.34094 1.000 71.86286  ? 443 VAL B CG2 1 
ATOM   7333 N  N   . ILE B 1 444 ? 50.62659  1.22256   -56.04970 1.000 56.78748  ? 444 ILE B N   1 
ATOM   7334 C  CA  . ILE B 1 444 ? 49.20064  1.30530   -56.33887 1.000 61.03661  ? 444 ILE B CA  1 
ATOM   7335 C  C   . ILE B 1 444 ? 48.96312  0.86981   -57.77963 1.000 67.23914  ? 444 ILE B C   1 
ATOM   7336 O  O   . ILE B 1 444 ? 49.76486  1.17253   -58.67002 1.000 75.17665  ? 444 ILE B O   1 
ATOM   7337 C  CB  . ILE B 1 444 ? 48.66189  2.73284   -56.08895 1.000 58.74681  ? 444 ILE B CB  1 
ATOM   7338 C  CG1 . ILE B 1 444 ? 48.68911  3.06272   -54.59789 1.000 71.02422  ? 444 ILE B CG1 1 
ATOM   7339 C  CG2 . ILE B 1 444 ? 47.24614  2.88554   -56.62299 1.000 60.25474  ? 444 ILE B CG2 1 
ATOM   7340 C  CD1 . ILE B 1 444 ? 47.63199  2.34177   -53.79368 1.000 58.25684  ? 444 ILE B CD1 1 
ATOM   7341 N  N   . SER B 1 445 ? 47.86830  0.14746   -58.00326 1.000 60.52169  ? 445 SER B N   1 
ATOM   7342 C  CA  . SER B 1 445 ? 47.51467  -0.32097  -59.33668 1.000 58.60696  ? 445 SER B CA  1 
ATOM   7343 C  C   . SER B 1 445 ? 46.01250  -0.57757  -59.38433 1.000 66.85273  ? 445 SER B C   1 
ATOM   7344 O  O   . SER B 1 445 ? 45.31813  -0.53355  -58.36555 1.000 66.97326  ? 445 SER B O   1 
ATOM   7345 C  CB  . SER B 1 445 ? 48.30861  -1.57913  -59.71067 1.000 67.99230  ? 445 SER B CB  1 
ATOM   7346 O  OG  . SER B 1 445 ? 47.99926  -2.02322  -61.01899 1.000 62.68689  ? 445 SER B OG  1 
ATOM   7347 N  N   . SER B 1 446 ? 45.51483  -0.81367  -60.59411 1.000 59.01430  ? 446 SER B N   1 
ATOM   7348 C  CA  . SER B 1 446 ? 44.14730  -1.25957  -60.82245 1.000 60.21078  ? 446 SER B CA  1 
ATOM   7349 C  C   . SER B 1 446 ? 44.18030  -2.73071  -61.20703 1.000 76.64879  ? 446 SER B C   1 
ATOM   7350 O  O   . SER B 1 446 ? 44.94691  -3.12453  -62.09067 1.000 97.95350  ? 446 SER B O   1 
ATOM   7351 C  CB  . SER B 1 446 ? 43.47664  -0.44144  -61.92627 1.000 61.61677  ? 446 SER B CB  1 
ATOM   7352 O  OG  . SER B 1 446 ? 44.15755  -0.60888  -63.15836 1.000 66.30583  ? 446 SER B OG  1 
ATOM   7353 N  N   . ASP B 1 447 ? 43.34585  -3.53953  -60.55893 1.000 72.81404  ? 447 ASP B N   1 
ATOM   7354 C  CA  . ASP B 1 447 ? 43.36409  -4.97436  -60.83010 1.000 71.60347  ? 447 ASP B CA  1 
ATOM   7355 C  C   . ASP B 1 447 ? 42.81181  -5.27316  -62.21947 1.000 65.91560  ? 447 ASP B C   1 
ATOM   7356 O  O   . ASP B 1 447 ? 43.52035  -5.79421  -63.08863 1.000 57.65521  ? 447 ASP B O   1 
ATOM   7357 C  CB  . ASP B 1 447 ? 42.56498  -5.71819  -59.75497 1.000 61.95796  ? 447 ASP B CB  1 
ATOM   7358 C  CG  . ASP B 1 447 ? 42.89861  -7.19421  -59.69164 1.000 84.07480  ? 447 ASP B CG  1 
ATOM   7359 O  OD1 . ASP B 1 447 ? 44.07794  -7.52325  -59.45524 1.000 80.93783  ? 447 ASP B OD1 1 
ATOM   7360 O  OD2 . ASP B 1 447 ? 41.98033  -8.02443  -59.85932 1.000 101.40488 ? 447 ASP B OD2 1 
ATOM   7361 N  N   . ASP B 1 448 ? 41.54814  -4.93215  -62.44954 1.000 68.59727  ? 448 ASP B N   1 
ATOM   7362 C  CA  . ASP B 1 448 ? 40.86843  -5.16912  -63.72162 1.000 61.09261  ? 448 ASP B CA  1 
ATOM   7363 C  C   . ASP B 1 448 ? 40.10493  -3.90881  -64.10319 1.000 58.95112  ? 448 ASP B C   1 
ATOM   7364 O  O   . ASP B 1 448 ? 38.87295  -3.85736  -64.00090 1.000 56.81143  ? 448 ASP B O   1 
ATOM   7365 C  CB  . ASP B 1 448 ? 39.93957  -6.37826  -63.61779 1.000 72.41305  ? 448 ASP B CB  1 
ATOM   7366 C  CG  . ASP B 1 448 ? 40.69383  -7.66688  -63.36048 1.000 85.44382  ? 448 ASP B CG  1 
ATOM   7367 O  OD1 . ASP B 1 448 ? 41.46914  -8.08578  -64.24484 1.000 82.87589  ? 448 ASP B OD1 1 
ATOM   7368 O  OD2 . ASP B 1 448 ? 40.52598  -8.25005  -62.26986 1.000 89.11873  ? 448 ASP B OD2 1 
ATOM   7369 N  N   . PRO B 1 449 ? 40.81382  -2.86379  -64.54126 1.000 63.95546  ? 449 PRO B N   1 
ATOM   7370 C  CA  . PRO B 1 449 ? 40.15248  -1.56281  -64.73528 1.000 56.14120  ? 449 PRO B CA  1 
ATOM   7371 C  C   . PRO B 1 449 ? 39.00987  -1.58983  -65.73786 1.000 55.59085  ? 449 PRO B C   1 
ATOM   7372 O  O   . PRO B 1 449 ? 38.02225  -0.87150  -65.54691 1.000 45.91870  ? 449 PRO B O   1 
ATOM   7373 C  CB  . PRO B 1 449 ? 41.30075  -0.65803  -65.20511 1.000 56.19161  ? 449 PRO B CB  1 
ATOM   7374 C  CG  . PRO B 1 449 ? 42.30213  -1.59411  -65.79754 1.000 49.04125  ? 449 PRO B CG  1 
ATOM   7375 C  CD  . PRO B 1 449 ? 42.22912  -2.82920  -64.94707 1.000 70.60568  ? 449 PRO B CD  1 
ATOM   7376 N  N   . GLY B 1 450 ? 39.10091  -2.40222  -66.79402 1.000 64.38337  ? 450 GLY B N   1 
ATOM   7377 C  CA  . GLY B 1 450 ? 38.03827  -2.44945  -67.78345 1.000 51.03796  ? 450 GLY B CA  1 
ATOM   7378 C  C   . GLY B 1 450 ? 36.80694  -3.21918  -67.35702 1.000 56.99484  ? 450 GLY B C   1 
ATOM   7379 O  O   . GLY B 1 450 ? 35.72328  -2.97919  -67.89919 1.000 46.32836  ? 450 GLY B O   1 
ATOM   7380 N  N   . ALA B 1 451 ? 36.94716  -4.13517  -66.39455 1.000 60.70578  ? 451 ALA B N   1 
ATOM   7381 C  CA  . ALA B 1 451 ? 35.80419  -4.92915  -65.95471 1.000 52.32891  ? 451 ALA B CA  1 
ATOM   7382 C  C   . ALA B 1 451 ? 34.74899  -4.06433  -65.27485 1.000 58.65800  ? 451 ALA B C   1 
ATOM   7383 O  O   . ALA B 1 451 ? 33.54723  -4.26055  -65.49217 1.000 51.04860  ? 451 ALA B O   1 
ATOM   7384 C  CB  . ALA B 1 451 ? 36.26628  -6.04720  -65.02256 1.000 52.97590  ? 451 ALA B CB  1 
ATOM   7385 N  N   . TRP B 1 452 ? 35.17205  -3.10924  -64.44472 1.000 68.16731  ? 452 TRP B N   1 
ATOM   7386 C  CA  . TRP B 1 452 ? 34.25123  -2.22117  -63.74581 1.000 66.97843  ? 452 TRP B CA  1 
ATOM   7387 C  C   . TRP B 1 452 ? 34.34268  -0.77779  -64.24102 1.000 63.68346  ? 452 TRP B C   1 
ATOM   7388 O  O   . TRP B 1 452 ? 34.15369  0.15970   -63.46270 1.000 67.68240  ? 452 TRP B O   1 
ATOM   7389 C  CB  . TRP B 1 452 ? 34.48424  -2.28791  -62.23694 1.000 57.16026  ? 452 TRP B CB  1 
ATOM   7390 C  CG  . TRP B 1 452 ? 35.92619  -2.33257  -61.82944 1.000 56.97709  ? 452 TRP B CG  1 
ATOM   7391 C  CD1 . TRP B 1 452 ? 36.80742  -1.29193  -61.81713 1.000 56.34989  ? 452 TRP B CD1 1 
ATOM   7392 C  CD2 . TRP B 1 452 ? 36.64845  -3.47514  -61.35312 1.000 63.93288  ? 452 TRP B CD2 1 
ATOM   7393 N  NE1 . TRP B 1 452 ? 38.03688  -1.71690  -61.37333 1.000 59.60105  ? 452 TRP B NE1 1 
ATOM   7394 C  CE2 . TRP B 1 452 ? 37.96509  -3.05343  -61.08078 1.000 66.67077  ? 452 TRP B CE2 1 
ATOM   7395 C  CE3 . TRP B 1 452 ? 36.31065  -4.81413  -61.13527 1.000 65.94083  ? 452 TRP B CE3 1 
ATOM   7396 C  CZ2 . TRP B 1 452 ? 38.94393  -3.92276  -60.60202 1.000 62.85804  ? 452 TRP B CZ2 1 
ATOM   7397 C  CZ3 . TRP B 1 452 ? 37.28359  -5.67592  -60.66004 1.000 70.27841  ? 452 TRP B CZ3 1 
ATOM   7398 C  CH2 . TRP B 1 452 ? 38.58451  -5.22688  -60.39885 1.000 58.83227  ? 452 TRP B CH2 1 
ATOM   7399 N  N   . GLU B 1 453 ? 34.63401  -0.59542  -65.53140 1.000 66.25691  ? 453 GLU B N   1 
ATOM   7400 C  CA  . GLU B 1 453 ? 34.58021  0.70411   -66.21143 1.000 69.02850  ? 453 GLU B CA  1 
ATOM   7401 C  C   . GLU B 1 453 ? 35.32550  1.78739   -65.43416 1.000 62.18303  ? 453 GLU B C   1 
ATOM   7402 O  O   . GLU B 1 453 ? 34.78872  2.85391   -65.12587 1.000 54.26126  ? 453 GLU B O   1 
ATOM   7403 C  CB  . GLU B 1 453 ? 33.13337  1.12388   -66.47431 1.000 66.40333  ? 453 GLU B CB  1 
ATOM   7404 C  CG  . GLU B 1 453 ? 32.36746  0.20502   -67.41314 1.000 69.86315  ? 453 GLU B CG  1 
ATOM   7405 C  CD  . GLU B 1 453 ? 30.97294  0.72239   -67.71381 1.000 79.91532  ? 453 GLU B CD  1 
ATOM   7406 O  OE1 . GLU B 1 453 ? 30.79390  1.95713   -67.74122 1.000 87.84759  ? 453 GLU B OE1 1 
ATOM   7407 O  OE2 . GLU B 1 453 ? 30.05567  -0.10021  -67.91719 1.000 61.70619  ? 453 GLU B OE2 1 
ATOM   7408 N  N   . ALA B 1 454 ? 36.57884  1.49973   -65.10818 1.000 59.21913  ? 454 ALA B N   1 
ATOM   7409 C  CA  . ALA B 1 454 ? 37.43820  2.42550   -64.39008 1.000 48.96318  ? 454 ALA B CA  1 
ATOM   7410 C  C   . ALA B 1 454 ? 38.61119  2.83333   -65.27212 1.000 55.69929  ? 454 ALA B C   1 
ATOM   7411 O  O   . ALA B 1 454 ? 38.89808  2.21315   -66.29926 1.000 58.27192  ? 454 ALA B O   1 
ATOM   7412 C  CB  . ALA B 1 454 ? 37.93758  1.81271   -63.07620 1.000 54.05731  ? 454 ALA B CB  1 
ATOM   7413 N  N   . SER B 1 455 ? 39.29231  3.89409   -64.84880 1.000 65.43731  ? 455 SER B N   1 
ATOM   7414 C  CA  . SER B 1 455 ? 40.43642  4.40463   -65.57865 1.000 67.86960  ? 455 SER B CA  1 
ATOM   7415 C  C   . SER B 1 455 ? 41.62848  3.45944   -65.44475 1.000 68.81735  ? 455 SER B C   1 
ATOM   7416 O  O   . SER B 1 455 ? 41.64308  2.58247   -64.57782 1.000 59.97026  ? 455 SER B O   1 
ATOM   7417 C  CB  . SER B 1 455 ? 40.80248  5.79688   -65.06799 1.000 56.08844  ? 455 SER B CB  1 
ATOM   7418 O  OG  . SER B 1 455 ? 40.10480  6.78880   -65.79682 1.000 80.03135  ? 455 SER B OG  1 
ATOM   7419 N  N   . PRO B 1 456 ? 42.63085  3.59441   -66.32917 1.000 59.15740  ? 456 PRO B N   1 
ATOM   7420 C  CA  . PRO B 1 456 ? 43.84359  2.77524   -66.19837 1.000 57.46996  ? 456 PRO B CA  1 
ATOM   7421 C  C   . PRO B 1 456 ? 44.47140  2.88185   -64.81720 1.000 68.17745  ? 456 PRO B C   1 
ATOM   7422 O  O   . PRO B 1 456 ? 44.61834  1.87325   -64.12120 1.000 79.18189  ? 456 PRO B O   1 
ATOM   7423 C  CB  . PRO B 1 456 ? 44.76679  3.34810   -67.28083 1.000 64.86723  ? 456 PRO B CB  1 
ATOM   7424 C  CG  . PRO B 1 456 ? 43.83607  3.89252   -68.30787 1.000 69.04692  ? 456 PRO B CG  1 
ATOM   7425 C  CD  . PRO B 1 456 ? 42.64953  4.41785   -67.55312 1.000 60.81048  ? 456 PRO B CD  1 
ATOM   7426 N  N   . LEU B 1 457 ? 44.83995  4.09512   -64.40461 1.000 66.38393  ? 457 LEU B N   1 
ATOM   7427 C  CA  . LEU B 1 457 ? 45.40928  4.29323   -63.07399 1.000 63.30416  ? 457 LEU B CA  1 
ATOM   7428 C  C   . LEU B 1 457 ? 44.89821  5.52794   -62.34498 1.000 70.28911  ? 457 LEU B C   1 
ATOM   7429 O  O   . LEU B 1 457 ? 45.09338  5.61733   -61.12835 1.000 64.37111  ? 457 LEU B O   1 
ATOM   7430 C  CB  . LEU B 1 457 ? 46.93975  4.36297   -63.16164 1.000 50.74967  ? 457 LEU B CB  1 
ATOM   7431 C  CG  . LEU B 1 457 ? 47.73049  4.04162   -61.89425 1.000 48.83146  ? 457 LEU B CG  1 
ATOM   7432 C  CD1 . LEU B 1 457 ? 47.19655  2.77300   -61.25444 1.000 60.42262  ? 457 LEU B CD1 1 
ATOM   7433 C  CD2 . LEU B 1 457 ? 49.21076  3.90162   -62.21463 1.000 58.01817  ? 457 LEU B CD2 1 
ATOM   7434 N  N   . SER B 1 458 ? 44.24342  6.47491   -63.02109 1.000 74.07413  ? 458 SER B N   1 
ATOM   7435 C  CA  . SER B 1 458 ? 43.80864  7.70174   -62.35807 1.000 73.26321  ? 458 SER B CA  1 
ATOM   7436 C  C   . SER B 1 458 ? 42.71355  7.42754   -61.33317 1.000 68.93251  ? 458 SER B C   1 
ATOM   7437 O  O   . SER B 1 458 ? 42.76614  7.93247   -60.20583 1.000 62.02684  ? 458 SER B O   1 
ATOM   7438 C  CB  . SER B 1 458 ? 43.32832  8.71585   -63.39662 1.000 64.06201  ? 458 SER B CB  1 
ATOM   7439 O  OG  . SER B 1 458 ? 44.40740  9.25184   -64.13959 1.000 61.28117  ? 458 SER B OG  1 
ATOM   7440 N  N   . HIS B 1 459 ? 41.70789  6.63213   -61.70922 1.000 67.03944  ? 459 HIS B N   1 
ATOM   7441 C  CA  . HIS B 1 459 ? 40.58895  6.37427   -60.80757 1.000 58.66295  ? 459 HIS B CA  1 
ATOM   7442 C  C   . HIS B 1 459 ? 41.03005  5.64045   -59.54837 1.000 66.28358  ? 459 HIS B C   1 
ATOM   7443 O  O   . HIS B 1 459 ? 40.41144  5.79833   -58.49093 1.000 69.26532  ? 459 HIS B O   1 
ATOM   7444 C  CB  . HIS B 1 459 ? 39.49942  5.58512   -61.53355 1.000 67.71163  ? 459 HIS B CB  1 
ATOM   7445 C  CG  . HIS B 1 459 ? 38.46422  6.44916   -62.18388 1.000 66.10279  ? 459 HIS B CG  1 
ATOM   7446 N  ND1 . HIS B 1 459 ? 37.89498  6.14483   -63.40148 1.000 55.06626  ? 459 HIS B ND1 1 
ATOM   7447 C  CD2 . HIS B 1 459 ? 37.89158  7.60805   -61.78053 1.000 69.02996  ? 459 HIS B CD2 1 
ATOM   7448 C  CE1 . HIS B 1 459 ? 37.01938  7.08059   -63.72193 1.000 68.87300  ? 459 HIS B CE1 1 
ATOM   7449 N  NE2 . HIS B 1 459 ? 36.99775  7.97988   -62.75492 1.000 75.63697  ? 459 HIS B NE2 1 
ATOM   7450 N  N   . ASP B 1 460 ? 42.08642  4.83420   -59.63614 1.000 71.51427  ? 460 ASP B N   1 
ATOM   7451 C  CA  . ASP B 1 460 ? 42.61410  4.17072   -58.45100 1.000 65.90942  ? 460 ASP B CA  1 
ATOM   7452 C  C   . ASP B 1 460 ? 43.56587  5.06071   -57.66190 1.000 65.33414  ? 460 ASP B C   1 
ATOM   7453 O  O   . ASP B 1 460 ? 43.75225  4.83439   -56.46122 1.000 75.03566  ? 460 ASP B O   1 
ATOM   7454 C  CB  . ASP B 1 460 ? 43.31209  2.86492   -58.84285 1.000 81.06121  ? 460 ASP B CB  1 
ATOM   7455 C  CG  . ASP B 1 460 ? 42.36556  1.87106   -59.50025 1.000 96.67471  ? 460 ASP B CG  1 
ATOM   7456 O  OD1 . ASP B 1 460 ? 41.96036  2.10539   -60.66066 1.000 87.70118  ? 460 ASP B OD1 1 
ATOM   7457 O  OD2 . ASP B 1 460 ? 42.02543  0.85684   -58.85390 1.000 85.68954  ? 460 ASP B OD2 1 
ATOM   7458 N  N   . PHE B 1 461 ? 44.17357  6.05834   -58.30837 1.000 64.00613  ? 461 PHE B N   1 
ATOM   7459 C  CA  . PHE B 1 461 ? 44.98901  7.02477   -57.58059 1.000 66.34024  ? 461 PHE B CA  1 
ATOM   7460 C  C   . PHE B 1 461 ? 44.12006  8.00036   -56.79659 1.000 68.27626  ? 461 PHE B C   1 
ATOM   7461 O  O   . PHE B 1 461 ? 44.45781  8.37321   -55.66659 1.000 70.93543  ? 461 PHE B O   1 
ATOM   7462 C  CB  . PHE B 1 461 ? 45.89712  7.77974   -58.54975 1.000 61.70554  ? 461 PHE B CB  1 
ATOM   7463 C  CG  . PHE B 1 461 ? 47.33401  7.34981   -58.49937 1.000 63.29984  ? 461 PHE B CG  1 
ATOM   7464 C  CD1 . PHE B 1 461 ? 47.71357  6.09522   -58.94481 1.000 73.55784  ? 461 PHE B CD1 1 
ATOM   7465 C  CD2 . PHE B 1 461 ? 48.30815  8.20602   -58.01678 1.000 58.15908  ? 461 PHE B CD2 1 
ATOM   7466 C  CE1 . PHE B 1 461 ? 49.03775  5.70158   -58.90174 1.000 75.03515  ? 461 PHE B CE1 1 
ATOM   7467 C  CE2 . PHE B 1 461 ? 49.63245  7.81885   -57.97170 1.000 56.73754  ? 461 PHE B CE2 1 
ATOM   7468 C  CZ  . PHE B 1 461 ? 49.99823  6.56580   -58.41450 1.000 62.09657  ? 461 PHE B CZ  1 
ATOM   7469 N  N   . TYR B 1 462 ? 42.99803  8.42550   -57.38296 1.000 59.17006  ? 462 TYR B N   1 
ATOM   7470 C  CA  . TYR B 1 462 ? 42.11462  9.37724   -56.71454 1.000 47.16459  ? 462 TYR B CA  1 
ATOM   7471 C  C   . TYR B 1 462 ? 41.52803  8.78928   -55.43707 1.000 63.81082  ? 462 TYR B C   1 
ATOM   7472 O  O   . TYR B 1 462 ? 41.45948  9.47087   -54.40800 1.000 72.87830  ? 462 TYR B O   1 
ATOM   7473 C  CB  . TYR B 1 462 ? 40.99851  9.81095   -57.66794 1.000 57.01554  ? 462 TYR B CB  1 
ATOM   7474 C  CG  . TYR B 1 462 ? 40.04884  10.83832  -57.08851 1.000 58.64924  ? 462 TYR B CG  1 
ATOM   7475 C  CD1 . TYR B 1 462 ? 40.32861  12.19601  -57.17483 1.000 62.58410  ? 462 TYR B CD1 1 
ATOM   7476 C  CD2 . TYR B 1 462 ? 38.86986  10.45188  -56.46506 1.000 57.39751  ? 462 TYR B CD2 1 
ATOM   7477 C  CE1 . TYR B 1 462 ? 39.46380  13.13910  -56.64974 1.000 66.58750  ? 462 TYR B CE1 1 
ATOM   7478 C  CE2 . TYR B 1 462 ? 37.99968  11.38806  -55.93635 1.000 62.69892  ? 462 TYR B CE2 1 
ATOM   7479 C  CZ  . TYR B 1 462 ? 38.30186  12.73013  -56.03238 1.000 73.84564  ? 462 TYR B CZ  1 
ATOM   7480 O  OH  . TYR B 1 462 ? 37.44005  13.66755  -55.50940 1.000 82.36236  ? 462 TYR B OH  1 
ATOM   7481 N  N   . VAL B 1 463 ? 41.08770  7.52962   -55.48611 1.000 60.03373  ? 463 VAL B N   1 
ATOM   7482 C  CA  . VAL B 1 463 ? 40.53150  6.88872   -54.29588 1.000 62.40343  ? 463 VAL B CA  1 
ATOM   7483 C  C   . VAL B 1 463 ? 41.58600  6.80020   -53.19930 1.000 64.54451  ? 463 VAL B C   1 
ATOM   7484 O  O   . VAL B 1 463 ? 41.28647  6.97407   -52.01184 1.000 60.13881  ? 463 VAL B O   1 
ATOM   7485 C  CB  . VAL B 1 463 ? 39.95440  5.50521   -54.65091 1.000 55.01966  ? 463 VAL B CB  1 
ATOM   7486 C  CG1 . VAL B 1 463 ? 39.53554  4.75444   -53.39408 1.000 56.00932  ? 463 VAL B CG1 1 
ATOM   7487 C  CG2 . VAL B 1 463 ? 38.77198  5.65353   -55.59915 1.000 52.23080  ? 463 VAL B CG2 1 
ATOM   7488 N  N   . ALA B 1 464 ? 42.83794  6.53363   -53.57887 1.000 59.77414  ? 464 ALA B N   1 
ATOM   7489 C  CA  . ALA B 1 464 ? 43.92282  6.53439   -52.60222 1.000 66.14714  ? 464 ALA B CA  1 
ATOM   7490 C  C   . ALA B 1 464 ? 44.12028  7.91956   -51.99828 1.000 66.69970  ? 464 ALA B C   1 
ATOM   7491 O  O   . ALA B 1 464 ? 44.37680  8.05312   -50.79539 1.000 65.17011  ? 464 ALA B O   1 
ATOM   7492 C  CB  . ALA B 1 464 ? 45.21471  6.04177   -53.25414 1.000 65.00849  ? 464 ALA B CB  1 
ATOM   7493 N  N   . LEU B 1 465 ? 44.00614  8.96271   -52.82115 1.000 56.16671  ? 465 LEU B N   1 
ATOM   7494 C  CA  . LEU B 1 465 ? 44.20589  10.32363  -52.33582 1.000 58.42132  ? 465 LEU B CA  1 
ATOM   7495 C  C   . LEU B 1 465 ? 43.11774  10.73759  -51.34958 1.000 65.36875  ? 465 LEU B C   1 
ATOM   7496 O  O   . LEU B 1 465 ? 43.39606  11.44626  -50.37691 1.000 76.32183  ? 465 LEU B O   1 
ATOM   7497 C  CB  . LEU B 1 465 ? 44.25813  11.28829  -53.52141 1.000 57.22591  ? 465 LEU B CB  1 
ATOM   7498 C  CG  . LEU B 1 465 ? 44.17920  12.78333  -53.21500 1.000 48.97748  ? 465 LEU B CG  1 
ATOM   7499 C  CD1 . LEU B 1 465 ? 45.47416  13.25771  -52.58711 1.000 58.76270  ? 465 LEU B CD1 1 
ATOM   7500 C  CD2 . LEU B 1 465 ? 43.85690  13.57317  -54.47193 1.000 48.68927  ? 465 LEU B CD2 1 
ATOM   7501 N  N   . MET B 1 466 ? 41.87787  10.29838  -51.57194 1.000 60.83087  ? 466 MET B N   1 
ATOM   7502 C  CA  . MET B 1 466 ? 40.74498  10.77400  -50.78621 1.000 49.51198  ? 466 MET B CA  1 
ATOM   7503 C  C   . MET B 1 466 ? 40.33872  9.84123   -49.65113 1.000 54.75767  ? 466 MET B C   1 
ATOM   7504 O  O   . MET B 1 466 ? 39.65746  10.29124  -48.72317 1.000 54.38694  ? 466 MET B O   1 
ATOM   7505 C  CB  . MET B 1 466 ? 39.53128  11.00415  -51.69556 1.000 55.58306  ? 466 MET B CB  1 
ATOM   7506 C  CG  . MET B 1 466 ? 39.83028  11.84483  -52.92730 1.000 67.85489  ? 466 MET B CG  1 
ATOM   7507 S  SD  . MET B 1 466 ? 40.04944  13.59270  -52.55015 1.000 64.96884  ? 466 MET B SD  1 
ATOM   7508 C  CE  . MET B 1 466 ? 38.40950  14.01842  -51.96768 1.000 58.01750  ? 466 MET B CE  1 
ATOM   7509 N  N   . ASP B 1 467 ? 40.73573  8.56565   -49.69207 1.000 61.40819  ? 467 ASP B N   1 
ATOM   7510 C  CA  . ASP B 1 467 ? 40.28986  7.58359   -48.71251 1.000 50.87729  ? 467 ASP B CA  1 
ATOM   7511 C  C   . ASP B 1 467 ? 41.41261  6.89275   -47.95307 1.000 53.17141  ? 467 ASP B C   1 
ATOM   7512 O  O   . ASP B 1 467 ? 41.17167  6.42171   -46.83624 1.000 50.16064  ? 467 ASP B O   1 
ATOM   7513 C  CB  . ASP B 1 467 ? 39.43491  6.49543   -49.38552 1.000 51.91159  ? 467 ASP B CB  1 
ATOM   7514 C  CG  . ASP B 1 467 ? 38.20396  7.05611   -50.06595 1.000 58.56749  ? 467 ASP B CG  1 
ATOM   7515 O  OD1 . ASP B 1 467 ? 37.50460  7.87951   -49.44209 1.000 62.99224  ? 467 ASP B OD1 1 
ATOM   7516 O  OD2 . ASP B 1 467 ? 37.93810  6.67295   -51.22447 1.000 57.46511  ? 467 ASP B OD2 1 
ATOM   7517 N  N   . LEU B 1 468 ? 42.62314  6.82447   -48.50712 1.000 50.81737  ? 468 LEU B N   1 
ATOM   7518 C  CA  . LEU B 1 468 ? 43.68510  6.01416   -47.92198 1.000 56.68619  ? 468 LEU B CA  1 
ATOM   7519 C  C   . LEU B 1 468 ? 44.72803  6.82062   -47.15775 1.000 64.37570  ? 468 LEU B C   1 
ATOM   7520 O  O   . LEU B 1 468 ? 45.54443  6.22275   -46.44819 1.000 60.49493  ? 468 LEU B O   1 
ATOM   7521 C  CB  . LEU B 1 468 ? 44.38118  5.19134   -49.01136 1.000 63.99422  ? 468 LEU B CB  1 
ATOM   7522 C  CG  . LEU B 1 468 ? 43.49735  4.18786   -49.75516 1.000 68.81990  ? 468 LEU B CG  1 
ATOM   7523 C  CD1 . LEU B 1 468 ? 44.31512  3.37764   -50.75140 1.000 52.86698  ? 468 LEU B CD1 1 
ATOM   7524 C  CD2 . LEU B 1 468 ? 42.78553  3.27573   -48.77356 1.000 43.01202  ? 468 LEU B CD2 1 
ATOM   7525 N  N   . CYS B 1 469 ? 44.72651  8.14612   -47.27632 1.000 75.48422  ? 469 CYS B N   1 
ATOM   7526 C  CA  . CYS B 1 469 ? 45.63743  8.99086   -46.52089 1.000 69.66904  ? 469 CYS B CA  1 
ATOM   7527 C  C   . CYS B 1 469 ? 44.84519  10.06636  -45.79097 1.000 68.87740  ? 469 CYS B C   1 
ATOM   7528 O  O   . CYS B 1 469 ? 43.63065  10.20377  -45.96029 1.000 73.04719  ? 469 CYS B O   1 
ATOM   7529 C  CB  . CYS B 1 469 ? 46.70083  9.62876   -47.42767 1.000 60.72451  ? 469 CYS B CB  1 
ATOM   7530 S  SG  . CYS B 1 469 ? 46.03961  10.63121  -48.76709 1.000 86.30396  ? 469 CYS B SG  1 
ATOM   7531 N  N   . GLY B 1 470 ? 45.55737  10.84266  -44.97540 1.000 64.84658  ? 470 GLY B N   1 
ATOM   7532 C  CA  . GLY B 1 470 ? 44.92882  11.81312  -44.10759 1.000 67.44793  ? 470 GLY B CA  1 
ATOM   7533 C  C   . GLY B 1 470 ? 44.50497  13.08027  -44.82289 1.000 77.18571  ? 470 GLY B C   1 
ATOM   7534 O  O   . GLY B 1 470 ? 44.74817  13.28763  -46.01150 1.000 70.16190  ? 470 GLY B O   1 
ATOM   7535 N  N   . ARG B 1 471 ? 43.85299  13.95314  -44.05266 1.000 74.21927  ? 471 ARG B N   1 
ATOM   7536 C  CA  . ARG B 1 471 ? 43.36685  15.23564  -44.54535 1.000 68.54989  ? 471 ARG B CA  1 
ATOM   7537 C  C   . ARG B 1 471 ? 44.49425  16.20998  -44.87278 1.000 71.79670  ? 471 ARG B C   1 
ATOM   7538 O  O   . ARG B 1 471 ? 44.25125  17.19421  -45.57858 1.000 66.83466  ? 471 ARG B O   1 
ATOM   7539 C  CB  . ARG B 1 471 ? 42.42040  15.84640  -43.50246 1.000 68.24950  ? 471 ARG B CB  1 
ATOM   7540 C  CG  . ARG B 1 471 ? 41.73986  17.15748  -43.89048 1.000 69.72079  ? 471 ARG B CG  1 
ATOM   7541 C  CD  . ARG B 1 471 ? 41.05801  17.79214  -42.68061 1.000 74.15986  ? 471 ARG B CD  1 
ATOM   7542 N  NE  . ARG B 1 471 ? 40.49563  19.10637  -42.97150 1.000 64.96616  ? 471 ARG B NE  1 
ATOM   7543 C  CZ  . ARG B 1 471 ? 41.07846  20.25725  -42.66472 1.000 73.69312  ? 471 ARG B CZ  1 
ATOM   7544 N  NH1 . ARG B 1 471 ? 42.24935  20.29755  -42.05043 1.000 80.80001  ? 471 ARG B NH1 1 
ATOM   7545 N  NH2 . ARG B 1 471 ? 40.46906  21.39713  -42.97867 1.000 66.49548  ? 471 ARG B NH2 1 
ATOM   7546 N  N   . ASP B 1 472 ? 45.71880  15.95647  -44.40487 1.000 68.64782  ? 472 ASP B N   1 
ATOM   7547 C  CA  . ASP B 1 472 ? 46.82663  16.89160  -44.56589 1.000 63.24931  ? 472 ASP B CA  1 
ATOM   7548 C  C   . ASP B 1 472 ? 47.93008  16.35424  -45.47851 1.000 75.14966  ? 472 ASP B C   1 
ATOM   7549 O  O   . ASP B 1 472 ? 49.09006  16.75593  -45.33474 1.000 67.88567  ? 472 ASP B O   1 
ATOM   7550 C  CB  . ASP B 1 472 ? 47.40918  17.25555  -43.19771 1.000 76.89717  ? 472 ASP B CB  1 
ATOM   7551 C  CG  . ASP B 1 472 ? 46.40432  17.95345  -42.29411 1.000 86.98400  ? 472 ASP B CG  1 
ATOM   7552 O  OD1 . ASP B 1 472 ? 45.29142  18.27409  -42.76023 1.000 87.70052  ? 472 ASP B OD1 1 
ATOM   7553 O  OD2 . ASP B 1 472 ? 46.73179  18.18563  -41.11011 1.000 77.23888  ? 472 ASP B OD2 1 
ATOM   7554 N  N   . THR B 1 473 ? 47.59675  15.45274  -46.40793 1.000 80.87647  ? 473 THR B N   1 
ATOM   7555 C  CA  . THR B 1 473 ? 48.58374  14.78183  -47.25810 1.000 78.94201  ? 473 THR B CA  1 
ATOM   7556 C  C   . THR B 1 473 ? 48.01110  14.63049  -48.65762 1.000 71.02048  ? 473 THR B C   1 
ATOM   7557 O  O   . THR B 1 473 ? 47.04798  13.87674  -48.85346 1.000 73.25614  ? 473 THR B O   1 
ATOM   7558 C  CB  . THR B 1 473 ? 48.95724  13.41347  -46.69715 1.000 63.49152  ? 473 THR B CB  1 
ATOM   7559 O  OG1 . THR B 1 473 ? 49.42813  13.54758  -45.33960 1.000 70.68406  ? 473 THR B OG1 1 
ATOM   7560 C  CG2 . THR B 1 473 ? 50.04401  12.75458  -47.53815 1.000 65.38516  ? 473 THR B CG2 1 
ATOM   7561 N  N   . ALA B 1 474 ? 48.57320  15.36664  -49.62426 1.000 61.11600  ? 474 ALA B N   1 
ATOM   7562 C  CA  . ALA B 1 474 ? 48.16347  15.20614  -51.01764 1.000 49.95331  ? 474 ALA B CA  1 
ATOM   7563 C  C   . ALA B 1 474 ? 49.29761  14.80799  -51.95399 1.000 53.72081  ? 474 ALA B C   1 
ATOM   7564 O  O   . ALA B 1 474 ? 49.30625  13.66486  -52.42581 1.000 73.69176  ? 474 ALA B O   1 
ATOM   7565 C  CB  . ALA B 1 474 ? 47.49064  16.49734  -51.47936 1.000 58.90203  ? 474 ALA B CB  1 
ATOM   7566 N  N   . LEU B 1 475 ? 50.30595  15.66803  -52.16283 1.000 59.64528  ? 475 LEU B N   1 
ATOM   7567 C  CA  . LEU B 1 475 ? 51.21291  15.45843  -53.29524 1.000 65.61436  ? 475 LEU B CA  1 
ATOM   7568 C  C   . LEU B 1 475 ? 52.49119  14.70521  -52.93983 1.000 66.33194  ? 475 LEU B C   1 
ATOM   7569 O  O   . LEU B 1 475 ? 53.06397  14.02349  -53.79821 1.000 67.39280  ? 475 LEU B O   1 
ATOM   7570 C  CB  . LEU B 1 475 ? 51.59764  16.79862  -53.93734 1.000 58.51586  ? 475 LEU B CB  1 
ATOM   7571 C  CG  . LEU B 1 475 ? 52.09340  16.70696  -55.37631 1.000 49.27870  ? 475 LEU B CG  1 
ATOM   7572 C  CD1 . LEU B 1 475 ? 50.93150  16.55326  -56.35769 1.000 46.49475  ? 475 LEU B CD1 1 
ATOM   7573 C  CD2 . LEU B 1 475 ? 52.96463  17.89839  -55.74939 1.000 43.01178  ? 475 LEU B CD2 1 
ATOM   7574 N  N   . THR B 1 476 ? 52.96957  14.83804  -51.70464 1.000 73.41708  ? 476 THR B N   1 
ATOM   7575 C  CA  . THR B 1 476 ? 54.07353  14.00295  -51.23771 1.000 64.45185  ? 476 THR B CA  1 
ATOM   7576 C  C   . THR B 1 476 ? 53.72551  12.52299  -51.35440 1.000 69.39936  ? 476 THR B C   1 
ATOM   7577 O  O   . THR B 1 476 ? 54.55379  11.70736  -51.78001 1.000 77.25511  ? 476 THR B O   1 
ATOM   7578 C  CB  . THR B 1 476 ? 54.41258  14.36640  -49.78894 1.000 67.21831  ? 476 THR B CB  1 
ATOM   7579 O  OG1 . THR B 1 476 ? 53.19364  14.52739  -49.05298 1.000 79.54251  ? 476 THR B OG1 1 
ATOM   7580 C  CG2 . THR B 1 476 ? 55.19629  15.66771  -49.74716 1.000 59.14500  ? 476 THR B CG2 1 
ATOM   7581 N  N   . PHE B 1 477 ? 52.49581  12.16277  -50.98871 1.000 74.99806  ? 477 PHE B N   1 
ATOM   7582 C  CA  . PHE B 1 477 ? 52.06049  10.77286  -51.08414 1.000 70.72452  ? 477 PHE B CA  1 
ATOM   7583 C  C   . PHE B 1 477 ? 52.02423  10.30034  -52.53363 1.000 68.93920  ? 477 PHE B C   1 
ATOM   7584 O  O   . PHE B 1 477 ? 52.50621  9.20738   -52.85364 1.000 83.39213  ? 477 PHE B O   1 
ATOM   7585 C  CB  . PHE B 1 477 ? 50.68907  10.61818  -50.42245 1.000 76.56456  ? 477 PHE B CB  1 
ATOM   7586 C  CG  . PHE B 1 477 ? 50.07479  9.25972   -50.59106 1.000 65.94037  ? 477 PHE B CG  1 
ATOM   7587 C  CD1 . PHE B 1 477 ? 50.69714  8.13332   -50.08149 1.000 66.84377  ? 477 PHE B CD1 1 
ATOM   7588 C  CD2 . PHE B 1 477 ? 48.85644  9.11498   -51.23324 1.000 65.61161  ? 477 PHE B CD2 1 
ATOM   7589 C  CE1 . PHE B 1 477 ? 50.12723  6.88561   -50.23146 1.000 63.70811  ? 477 PHE B CE1 1 
ATOM   7590 C  CE2 . PHE B 1 477 ? 48.28071  7.87019   -51.38194 1.000 65.16738  ? 477 PHE B CE2 1 
ATOM   7591 C  CZ  . PHE B 1 477 ? 48.91638  6.75455   -50.87876 1.000 59.77018  ? 477 PHE B CZ  1 
ATOM   7592 N  N   . LEU B 1 478 ? 51.45635  11.11543  -53.42782 1.000 69.13070  ? 478 LEU B N   1 
ATOM   7593 C  CA  . LEU B 1 478 ? 51.34277  10.71563  -54.82792 1.000 64.38768  ? 478 LEU B CA  1 
ATOM   7594 C  C   . LEU B 1 478 ? 52.71207  10.58218  -55.48322 1.000 66.17476  ? 478 LEU B C   1 
ATOM   7595 O  O   . LEU B 1 478 ? 52.95167  9.64402   -56.25284 1.000 73.40586  ? 478 LEU B O   1 
ATOM   7596 C  CB  . LEU B 1 478 ? 50.47908  11.71985  -55.59219 1.000 61.70376  ? 478 LEU B CB  1 
ATOM   7597 C  CG  . LEU B 1 478 ? 49.03674  11.86977  -55.10488 1.000 67.42877  ? 478 LEU B CG  1 
ATOM   7598 C  CD1 . LEU B 1 478 ? 48.26566  12.85047  -55.97696 1.000 68.70613  ? 478 LEU B CD1 1 
ATOM   7599 C  CD2 . LEU B 1 478 ? 48.34080  10.51792  -55.06083 1.000 68.59975  ? 478 LEU B CD2 1 
ATOM   7600 N  N   . LYS B 1 479 ? 53.62204  11.51493  -55.19539 1.000 72.25846  ? 479 LYS B N   1 
ATOM   7601 C  CA  . LYS B 1 479 ? 54.94933  11.46502  -55.79986 1.000 67.00712  ? 479 LYS B CA  1 
ATOM   7602 C  C   . LYS B 1 479 ? 55.73475  10.25522  -55.31018 1.000 64.96515  ? 479 LYS B C   1 
ATOM   7603 O  O   . LYS B 1 479 ? 56.46312  9.62555   -56.08650 1.000 60.89886  ? 479 LYS B O   1 
ATOM   7604 C  CB  . LYS B 1 479 ? 55.71092  12.75588  -55.50278 1.000 76.29867  ? 479 LYS B CB  1 
ATOM   7605 C  CG  . LYS B 1 479 ? 56.93012  12.97455  -56.38485 1.000 80.09829  ? 479 LYS B CG  1 
ATOM   7606 C  CD  . LYS B 1 479 ? 57.60387  14.30283  -56.07970 1.000 82.08708  ? 479 LYS B CD  1 
ATOM   7607 C  CE  . LYS B 1 479 ? 58.80414  14.53441  -56.98324 1.000 78.61902  ? 479 LYS B CE  1 
ATOM   7608 N  NZ  . LYS B 1 479 ? 59.57911  15.73679  -56.56870 1.000 65.86646  ? 479 LYS B NZ  1 
ATOM   7609 N  N   . GLN B 1 480 ? 55.60970  9.92184   -54.02363 1.000 71.72980  ? 480 GLN B N   1 
ATOM   7610 C  CA  . GLN B 1 480 ? 56.29282  8.74343   -53.50245 1.000 71.03280  ? 480 GLN B CA  1 
ATOM   7611 C  C   . GLN B 1 480 ? 55.76810  7.47045   -54.15312 1.000 73.83671  ? 480 GLN B C   1 
ATOM   7612 O  O   . GLN B 1 480 ? 56.53466  6.53485   -54.40455 1.000 75.28982  ? 480 GLN B O   1 
ATOM   7613 C  CB  . GLN B 1 480 ? 56.14613  8.66951   -51.98284 1.000 67.19567  ? 480 GLN B CB  1 
ATOM   7614 C  CG  . GLN B 1 480 ? 56.97541  7.56619   -51.34528 1.000 61.93588  ? 480 GLN B CG  1 
ATOM   7615 C  CD  . GLN B 1 480 ? 58.46741  7.82282   -51.45858 1.000 66.81822  ? 480 GLN B CD  1 
ATOM   7616 O  OE1 . GLN B 1 480 ? 58.94009  8.92923   -51.19911 1.000 65.96409  ? 480 GLN B OE1 1 
ATOM   7617 N  NE2 . GLN B 1 480 ? 59.21499  6.80287   -51.85875 1.000 63.45968  ? 480 GLN B NE2 1 
ATOM   7618 N  N   . LEU B 1 481 ? 54.46061  7.40888   -54.41902 1.000 65.61632  ? 481 LEU B N   1 
ATOM   7619 C  CA  . LEU B 1 481 ? 53.90354  6.25867   -55.12633 1.000 61.88560  ? 481 LEU B CA  1 
ATOM   7620 C  C   . LEU B 1 481 ? 54.50440  6.12310   -56.51989 1.000 63.34134  ? 481 LEU B C   1 
ATOM   7621 O  O   . LEU B 1 481 ? 54.84159  5.01533   -56.95452 1.000 67.42026  ? 481 LEU B O   1 
ATOM   7622 C  CB  . LEU B 1 481 ? 52.38176  6.38179   -55.21043 1.000 54.09244  ? 481 LEU B CB  1 
ATOM   7623 C  CG  . LEU B 1 481 ? 51.61145  6.22494   -53.90168 1.000 49.70069  ? 481 LEU B CG  1 
ATOM   7624 C  CD1 . LEU B 1 481 ? 50.11806  6.31966   -54.15766 1.000 54.57858  ? 481 LEU B CD1 1 
ATOM   7625 C  CD2 . LEU B 1 481 ? 51.95988  4.90838   -53.22380 1.000 55.02869  ? 481 LEU B CD2 1 
ATOM   7626 N  N   . ALA B 1 482 ? 54.64102  7.24108   -57.23639 1.000 62.29767  ? 482 ALA B N   1 
ATOM   7627 C  CA  . ALA B 1 482 ? 55.23798  7.20151   -58.56721 1.000 62.69763  ? 482 ALA B CA  1 
ATOM   7628 C  C   . ALA B 1 482 ? 56.69040  6.74600   -58.51089 1.000 71.31357  ? 482 ALA B C   1 
ATOM   7629 O  O   . ALA B 1 482 ? 57.14087  5.98062   -59.36953 1.000 76.88656  ? 482 ALA B O   1 
ATOM   7630 C  CB  . ALA B 1 482 ? 55.12952  8.57295   -59.23166 1.000 51.92121  ? 482 ALA B CB  1 
ATOM   7631 N  N   . LEU B 1 483 ? 57.44306  7.21347   -57.51282 1.000 70.73773  ? 483 LEU B N   1 
ATOM   7632 C  CA  . LEU B 1 483 ? 58.82980  6.78072   -57.37456 1.000 66.16436  ? 483 LEU B CA  1 
ATOM   7633 C  C   . LEU B 1 483 ? 58.92880  5.34653   -56.86852 1.000 71.58775  ? 483 LEU B C   1 
ATOM   7634 O  O   . LEU B 1 483 ? 59.90036  4.64737   -57.17997 1.000 78.76060  ? 483 LEU B O   1 
ATOM   7635 C  CB  . LEU B 1 483 ? 59.58654  7.72990   -56.44791 1.000 73.03772  ? 483 LEU B CB  1 
ATOM   7636 C  CG  . LEU B 1 483 ? 60.03583  9.04044   -57.09541 1.000 79.11541  ? 483 LEU B CG  1 
ATOM   7637 C  CD1 . LEU B 1 483 ? 60.33003  10.10278  -56.04623 1.000 69.19617  ? 483 LEU B CD1 1 
ATOM   7638 C  CD2 . LEU B 1 483 ? 61.25699  8.79229   -57.96999 1.000 69.10994  ? 483 LEU B CD2 1 
ATOM   7639 N  N   . ASN B 1 484 ? 57.94593  4.89429   -56.08578 1.000 70.57649  ? 484 ASN B N   1 
ATOM   7640 C  CA  . ASN B 1 484 ? 57.96486  3.52294   -55.58643 1.000 72.06481  ? 484 ASN B CA  1 
ATOM   7641 C  C   . ASN B 1 484 ? 57.67544  2.51638   -56.69000 1.000 68.19719  ? 484 ASN B C   1 
ATOM   7642 O  O   . ASN B 1 484 ? 58.15508  1.37889   -56.62884 1.000 77.32918  ? 484 ASN B O   1 
ATOM   7643 C  CB  . ASN B 1 484 ? 56.95826  3.35857   -54.44738 1.000 75.99475  ? 484 ASN B CB  1 
ATOM   7644 C  CG  . ASN B 1 484 ? 57.50237  3.83200   -53.11556 1.000 74.55472  ? 484 ASN B CG  1 
ATOM   7645 O  OD1 . ASN B 1 484 ? 58.63062  4.31538   -53.03052 1.000 68.10277  ? 484 ASN B OD1 1 
ATOM   7646 N  ND2 . ASN B 1 484 ? 56.69890  3.69925   -52.06698 1.000 65.22613  ? 484 ASN B ND2 1 
ATOM   7647 N  N   . SER B 1 485 ? 56.89417  2.90689   -57.69851 1.000 69.82970  ? 485 SER B N   1 
ATOM   7648 C  CA  . SER B 1 485 ? 56.62753  2.00778   -58.81351 1.000 74.61268  ? 485 SER B CA  1 
ATOM   7649 C  C   . SER B 1 485 ? 57.87566  1.73209   -59.63987 1.000 74.03368  ? 485 SER B C   1 
ATOM   7650 O  O   . SER B 1 485 ? 57.91375  0.73513   -60.36839 1.000 69.09517  ? 485 SER B O   1 
ATOM   7651 C  CB  . SER B 1 485 ? 55.53492  2.58713   -59.70902 1.000 68.49379  ? 485 SER B CB  1 
ATOM   7652 O  OG  . SER B 1 485 ? 56.01679  3.71540   -60.41331 1.000 76.09613  ? 485 SER B OG  1 
ATOM   7653 N  N   . ILE B 1 486 ? 58.88836  2.58833   -59.54687 1.000 74.41078  ? 486 ILE B N   1 
ATOM   7654 C  CA  . ILE B 1 486 ? 60.14561  2.39097   -60.25322 1.000 70.75315  ? 486 ILE B CA  1 
ATOM   7655 C  C   . ILE B 1 486 ? 61.18113  1.70610   -59.37149 1.000 68.15097  ? 486 ILE B C   1 
ATOM   7656 O  O   . ILE B 1 486 ? 61.92465  0.84420   -59.84053 1.000 71.22969  ? 486 ILE B O   1 
ATOM   7657 C  CB  . ILE B 1 486 ? 60.67330  3.73987   -60.78589 1.000 68.38866  ? 486 ILE B CB  1 
ATOM   7658 C  CG1 . ILE B 1 486 ? 59.60381  4.42142   -61.63839 1.000 65.20341  ? 486 ILE B CG1 1 
ATOM   7659 C  CG2 . ILE B 1 486 ? 61.94153  3.53530   -61.59856 1.000 71.26800  ? 486 ILE B CG2 1 
ATOM   7660 C  CD1 . ILE B 1 486 ? 59.97013  5.81676   -62.06710 1.000 71.88083  ? 486 ILE B CD1 1 
ATOM   7661 N  N   . ARG B 1 487 ? 61.24658  2.08120   -58.09210 1.000 73.15644  ? 487 ARG B N   1 
ATOM   7662 C  CA  . ARG B 1 487 ? 62.18461  1.42886   -57.18588 1.000 70.00153  ? 487 ARG B CA  1 
ATOM   7663 C  C   . ARG B 1 487 ? 61.79776  -0.02464  -56.94712 1.000 76.90354  ? 487 ARG B C   1 
ATOM   7664 O  O   . ARG B 1 487 ? 62.64856  -0.92146  -56.98770 1.000 84.37048  ? 487 ARG B O   1 
ATOM   7665 C  CB  . ARG B 1 487 ? 62.26327  2.18035   -55.85875 1.000 71.45798  ? 487 ARG B CB  1 
ATOM   7666 C  CG  . ARG B 1 487 ? 63.08459  1.43184   -54.81957 1.000 84.18712  ? 487 ARG B CG  1 
ATOM   7667 C  CD  . ARG B 1 487 ? 63.16637  2.15357   -53.48584 1.000 95.48409  ? 487 ARG B CD  1 
ATOM   7668 N  NE  . ARG B 1 487 ? 64.06023  1.44911   -52.57350 1.000 107.22140 ? 487 ARG B NE  1 
ATOM   7669 C  CZ  . ARG B 1 487 ? 64.18441  1.71731   -51.28112 1.000 104.61349 ? 487 ARG B CZ  1 
ATOM   7670 N  NH1 . ARG B 1 487 ? 63.49135  2.68619   -50.70576 1.000 97.76411  ? 487 ARG B NH1 1 
ATOM   7671 N  NH2 . ARG B 1 487 ? 65.02140  0.99057   -50.54584 1.000 93.80413  ? 487 ARG B NH2 1 
ATOM   7672 N  N   . TYR B 1 488 ? 60.51210  -0.27726  -56.69560 1.000 70.29613  ? 488 TYR B N   1 
ATOM   7673 C  CA  . TYR B 1 488 ? 60.02470  -1.61537  -56.38734 1.000 67.58387  ? 488 TYR B CA  1 
ATOM   7674 C  C   . TYR B 1 488 ? 59.51032  -2.34598  -57.61928 1.000 85.75289  ? 488 TYR B C   1 
ATOM   7675 O  O   . TYR B 1 488 ? 58.61847  -3.19972  -57.51157 1.000 93.32408  ? 488 TYR B O   1 
ATOM   7676 C  CB  . TYR B 1 488 ? 58.95270  -1.53551  -55.30053 1.000 56.23149  ? 488 TYR B CB  1 
ATOM   7677 C  CG  . TYR B 1 488 ? 59.48520  -0.89691  -54.03945 1.000 79.25292  ? 488 TYR B CG  1 
ATOM   7678 C  CD1 . TYR B 1 488 ? 60.27425  -1.61875  -53.15412 1.000 71.26545  ? 488 TYR B CD1 1 
ATOM   7679 C  CD2 . TYR B 1 488 ? 59.22988  0.43695   -53.75043 1.000 78.43615  ? 488 TYR B CD2 1 
ATOM   7680 C  CE1 . TYR B 1 488 ? 60.77753  -1.03504  -52.00643 1.000 78.56702  ? 488 TYR B CE1 1 
ATOM   7681 C  CE2 . TYR B 1 488 ? 59.72834  1.02880   -52.60536 1.000 69.38471  ? 488 TYR B CE2 1 
ATOM   7682 C  CZ  . TYR B 1 488 ? 60.50104  0.28939   -51.73762 1.000 70.30042  ? 488 TYR B CZ  1 
ATOM   7683 O  OH  . TYR B 1 488 ? 60.99691  0.87834   -50.59728 1.000 85.28174  ? 488 TYR B OH  1 
ATOM   7684 N  N   . SER B 1 489 ? 60.05490  -2.02505  -58.78880 1.000 70.89846  ? 489 SER B N   1 
ATOM   7685 C  CA  . SER B 1 489 ? 59.76283  -2.73814  -60.01707 1.000 76.06716  ? 489 SER B CA  1 
ATOM   7686 C  C   . SER B 1 489 ? 60.71020  -3.92597  -60.15844 1.000 88.38826  ? 489 SER B C   1 
ATOM   7687 O  O   . SER B 1 489 ? 61.53625  -4.20691  -59.28663 1.000 96.82800  ? 489 SER B O   1 
ATOM   7688 C  CB  . SER B 1 489 ? 59.87994  -1.80136  -61.21778 1.000 79.03233  ? 489 SER B CB  1 
ATOM   7689 O  OG  . SER B 1 489 ? 61.21828  -1.36956  -61.38647 1.000 80.06620  ? 489 SER B OG  1 
ATOM   7690 N  N   . ALA B 1 490 ? 60.59309  -4.63276  -61.27913 1.000 81.89519  ? 490 ALA B N   1 
ATOM   7691 C  CA  . ALA B 1 490 ? 61.44635  -5.77333  -61.57478 1.000 66.17925  ? 490 ALA B CA  1 
ATOM   7692 C  C   . ALA B 1 490 ? 62.58313  -5.41964  -62.52365 1.000 66.38704  ? 490 ALA B C   1 
ATOM   7693 O  O   . ALA B 1 490 ? 63.26779  -6.32044  -63.01734 1.000 90.05667  ? 490 ALA B O   1 
ATOM   7694 C  CB  . ALA B 1 490 ? 60.61363  -6.91810  -62.15255 1.000 68.51159  ? 490 ALA B CB  1 
ATOM   7695 N  N   . MET B 1 491 ? 62.79646  -4.13411  -62.79175 1.000 64.24105  ? 491 MET B N   1 
ATOM   7696 C  CA  . MET B 1 491 ? 63.87634  -3.72032  -63.67356 1.000 76.40808  ? 491 MET B CA  1 
ATOM   7697 C  C   . MET B 1 491 ? 65.23278  -3.92305  -63.00182 1.000 78.94773  ? 491 MET B C   1 
ATOM   7698 O  O   . MET B 1 491 ? 65.35228  -3.96840  -61.77467 1.000 62.62056  ? 491 MET B O   1 
ATOM   7699 C  CB  . MET B 1 491 ? 63.71225  -2.25469  -64.07576 1.000 79.18917  ? 491 MET B CB  1 
ATOM   7700 C  CG  . MET B 1 491 ? 62.62004  -1.99936  -65.10106 1.000 68.08007  ? 491 MET B CG  1 
ATOM   7701 S  SD  . MET B 1 491 ? 62.45137  -0.25198  -65.51302 1.000 70.48309  ? 491 MET B SD  1 
ATOM   7702 C  CE  . MET B 1 491 ? 61.78862  0.38897   -63.97982 1.000 61.68811  ? 491 MET B CE  1 
ATOM   7703 N  N   . SER B 1 492 ? 66.26463  -4.05236  -63.83117 1.000 87.54631  ? 492 SER B N   1 
ATOM   7704 C  CA  . SER B 1 492 ? 67.62504  -4.10798  -63.32326 1.000 92.21905  ? 492 SER B CA  1 
ATOM   7705 C  C   . SER B 1 492 ? 68.02273  -2.75044  -62.75546 1.000 95.91953  ? 492 SER B C   1 
ATOM   7706 O  O   . SER B 1 492 ? 67.45005  -1.71498  -63.10178 1.000 104.66080 ? 492 SER B O   1 
ATOM   7707 C  CB  . SER B 1 492 ? 68.59943  -4.52708  -64.42424 1.000 93.75599  ? 492 SER B CB  1 
ATOM   7708 O  OG  . SER B 1 492 ? 68.58868  -3.59376  -65.49056 1.000 84.73550  ? 492 SER B OG  1 
ATOM   7709 N  N   . ASP B 1 493 ? 69.01080  -2.76582  -61.85533 1.000 90.22926  ? 493 ASP B N   1 
ATOM   7710 C  CA  . ASP B 1 493 ? 69.50204  -1.51406  -61.28382 1.000 92.66335  ? 493 ASP B CA  1 
ATOM   7711 C  C   . ASP B 1 493 ? 69.96273  -0.54382  -62.36370 1.000 84.29243  ? 493 ASP B C   1 
ATOM   7712 O  O   . ASP B 1 493 ? 69.82882  0.67421   -62.20107 1.000 80.82083  ? 493 ASP B O   1 
ATOM   7713 C  CB  . ASP B 1 493 ? 70.63685  -1.79689  -60.30077 1.000 97.08034  ? 493 ASP B CB  1 
ATOM   7714 C  CG  . ASP B 1 493 ? 70.19562  -2.66180  -59.13673 1.000 97.02178  ? 493 ASP B CG  1 
ATOM   7715 O  OD1 . ASP B 1 493 ? 69.05066  -2.49001  -58.65998 1.000 90.77168  ? 493 ASP B OD1 1 
ATOM   7716 O  OD2 . ASP B 1 493 ? 70.98939  -3.52347  -58.70319 1.000 108.51347 ? 493 ASP B OD2 1 
ATOM   7717 N  N   . THR B 1 494 ? 70.51404  -1.06020  -63.46306 1.000 89.01493  ? 494 THR B N   1 
ATOM   7718 C  CA  . THR B 1 494 ? 70.85419  -0.20719  -64.59825 1.000 82.05646  ? 494 THR B CA  1 
ATOM   7719 C  C   . THR B 1 494 ? 69.60065  0.39995   -65.21737 1.000 85.19857  ? 494 THR B C   1 
ATOM   7720 O  O   . THR B 1 494 ? 69.53286  1.61112   -65.45603 1.000 79.22685  ? 494 THR B O   1 
ATOM   7721 C  CB  . THR B 1 494 ? 71.63096  -1.01270  -65.64450 1.000 87.81685  ? 494 THR B CB  1 
ATOM   7722 O  OG1 . THR B 1 494 ? 72.66026  -1.77160  -64.99841 1.000 92.15191  ? 494 THR B OG1 1 
ATOM   7723 C  CG2 . THR B 1 494 ? 72.26386  -0.09106  -66.68165 1.000 92.67498  ? 494 THR B CG2 1 
ATOM   7724 N  N   . GLU B 1 495 ? 68.59427  -0.43718  -65.48422 1.000 86.31542  ? 495 GLU B N   1 
ATOM   7725 C  CA  . GLU B 1 495 ? 67.36890  0.03507   -66.12234 1.000 88.42418  ? 495 GLU B CA  1 
ATOM   7726 C  C   . GLU B 1 495 ? 66.62559  1.03481   -65.24491 1.000 86.51742  ? 495 GLU B C   1 
ATOM   7727 O  O   . GLU B 1 495 ? 66.06554  2.01612   -65.74723 1.000 81.26910  ? 495 GLU B O   1 
ATOM   7728 C  CB  . GLU B 1 495 ? 66.46510  -1.15139  -66.45714 1.000 87.13788  ? 495 GLU B CB  1 
ATOM   7729 C  CG  . GLU B 1 495 ? 66.89182  -1.94236  -67.68313 1.000 98.08995  ? 495 GLU B CG  1 
ATOM   7730 C  CD  . GLU B 1 495 ? 66.10009  -3.22470  -67.84354 1.000 104.85482 ? 495 GLU B CD  1 
ATOM   7731 O  OE1 . GLU B 1 495 ? 65.83373  -3.88541  -66.81735 1.000 103.13417 ? 495 GLU B OE1 1 
ATOM   7732 O  OE2 . GLU B 1 495 ? 65.74145  -3.56812  -68.99060 1.000 102.73625 ? 495 GLU B OE2 1 
ATOM   7733 N  N   . LYS B 1 496 ? 66.59524  0.79235   -63.93268 1.000 85.18340  ? 496 LYS B N   1 
ATOM   7734 C  CA  . LYS B 1 496 ? 65.86618  1.67175   -63.02244 1.000 79.37241  ? 496 LYS B CA  1 
ATOM   7735 C  C   . LYS B 1 496 ? 66.39131  3.10038   -63.08487 1.000 77.98361  ? 496 LYS B C   1 
ATOM   7736 O  O   . LYS B 1 496 ? 65.60984  4.05783   -63.04035 1.000 74.63167  ? 496 LYS B O   1 
ATOM   7737 C  CB  . LYS B 1 496 ? 65.96314  1.13636   -61.59361 1.000 64.12352  ? 496 LYS B CB  1 
ATOM   7738 C  CG  . LYS B 1 496 ? 65.21039  -0.16055  -61.35047 1.000 62.22268  ? 496 LYS B CG  1 
ATOM   7739 C  CD  . LYS B 1 496 ? 65.38782  -0.61411  -59.91060 1.000 72.94064  ? 496 LYS B CD  1 
ATOM   7740 C  CE  . LYS B 1 496 ? 64.53454  -1.83043  -59.59686 1.000 74.18777  ? 496 LYS B CE  1 
ATOM   7741 N  NZ  . LYS B 1 496 ? 64.83137  -2.39289  -58.24890 1.000 70.60135  ? 496 LYS B NZ  1 
ATOM   7742 N  N   . VAL B 1 497 ? 67.71290  3.26409   -63.17435 1.000 79.46998  ? 497 VAL B N   1 
ATOM   7743 C  CA  . VAL B 1 497 ? 68.29739  4.60124   -63.25210 1.000 68.94898  ? 497 VAL B CA  1 
ATOM   7744 C  C   . VAL B 1 497 ? 67.80787  5.32491   -64.50107 1.000 75.37725  ? 497 VAL B C   1 
ATOM   7745 O  O   . VAL B 1 497 ? 67.36926  6.47988   -64.44030 1.000 74.53245  ? 497 VAL B O   1 
ATOM   7746 C  CB  . VAL B 1 497 ? 69.83349  4.51634   -63.21338 1.000 69.39659  ? 497 VAL B CB  1 
ATOM   7747 C  CG1 . VAL B 1 497 ? 70.45311  5.89052   -63.42651 1.000 75.60486  ? 497 VAL B CG1 1 
ATOM   7748 C  CG2 . VAL B 1 497 ? 70.29830  3.91510   -61.89346 1.000 62.44162  ? 497 VAL B CG2 1 
ATOM   7749 N  N   . ALA B 1 498 ? 67.86673  4.65278   -65.65302 1.000 78.73614  ? 498 ALA B N   1 
ATOM   7750 C  CA  . ALA B 1 498 ? 67.40210  5.26224   -66.89331 1.000 85.51091  ? 498 ALA B CA  1 
ATOM   7751 C  C   . ALA B 1 498 ? 65.88563  5.40800   -66.93634 1.000 90.61444  ? 498 ALA B C   1 
ATOM   7752 O  O   . ALA B 1 498 ? 65.37405  6.21259   -67.72317 1.000 92.81139  ? 498 ALA B O   1 
ATOM   7753 C  CB  . ALA B 1 498 ? 67.88187  4.44609   -68.09363 1.000 82.47384  ? 498 ALA B CB  1 
ATOM   7754 N  N   . ALA B 1 499 ? 65.15745  4.64463   -66.11901 1.000 83.28432  ? 499 ALA B N   1 
ATOM   7755 C  CA  . ALA B 1 499 ? 63.70587  4.77223   -66.06720 1.000 82.33808  ? 499 ALA B CA  1 
ATOM   7756 C  C   . ALA B 1 499 ? 63.29354  5.94820   -65.19333 1.000 80.88248  ? 499 ALA B C   1 
ATOM   7757 O  O   . ALA B 1 499 ? 62.39128  6.71395   -65.55142 1.000 85.34750  ? 499 ALA B O   1 
ATOM   7758 C  CB  . ALA B 1 499 ? 63.08101  3.47514   -65.55348 1.000 85.66694  ? 499 ALA B CB  1 
ATOM   7759 N  N   . LYS B 1 500 ? 63.94628  6.09782   -64.03926 1.000 75.30146  ? 500 LYS B N   1 
ATOM   7760 C  CA  . LYS B 1 500 ? 63.71539  7.25836   -63.18773 1.000 73.78582  ? 500 LYS B CA  1 
ATOM   7761 C  C   . LYS B 1 500 ? 63.92559  8.55409   -63.95821 1.000 81.78652  ? 500 LYS B C   1 
ATOM   7762 O  O   . LYS B 1 500 ? 63.16024  9.50878   -63.79735 1.000 86.22935  ? 500 LYS B O   1 
ATOM   7763 C  CB  . LYS B 1 500 ? 64.64505  7.18808   -61.97189 1.000 67.60693  ? 500 LYS B CB  1 
ATOM   7764 C  CG  . LYS B 1 500 ? 64.40617  8.22367   -60.88250 1.000 64.14404  ? 500 LYS B CG  1 
ATOM   7765 C  CD  . LYS B 1 500 ? 65.43146  8.03620   -59.77000 1.000 76.56054  ? 500 LYS B CD  1 
ATOM   7766 C  CE  . LYS B 1 500 ? 65.21852  8.99581   -58.61407 1.000 91.64009  ? 500 LYS B CE  1 
ATOM   7767 N  NZ  . LYS B 1 500 ? 66.26282  8.80487   -57.56646 1.000 76.70832  ? 500 LYS B NZ  1 
ATOM   7768 N  N   . ALA B 1 501 ? 64.95378  8.60025   -64.80906 1.000 77.17766  ? 501 ALA B N   1 
ATOM   7769 C  CA  . ALA B 1 501 ? 65.22350  9.80348   -65.59250 1.000 72.46220  ? 501 ALA B CA  1 
ATOM   7770 C  C   . ALA B 1 501 ? 64.07006  10.12701  -66.53603 1.000 77.18646  ? 501 ALA B C   1 
ATOM   7771 O  O   . ALA B 1 501 ? 63.64196  11.28331  -66.63620 1.000 72.62014  ? 501 ALA B O   1 
ATOM   7772 C  CB  . ALA B 1 501 ? 66.52680  9.63996   -66.37371 1.000 67.63496  ? 501 ALA B CB  1 
ATOM   7773 N  N   . LYS B 1 502 ? 63.55902  9.11691   -67.24645 1.000 83.09549  ? 502 LYS B N   1 
ATOM   7774 C  CA  . LYS B 1 502 ? 62.45288  9.35451   -68.16980 1.000 81.54762  ? 502 LYS B CA  1 
ATOM   7775 C  C   . LYS B 1 502 ? 61.21985  9.85702   -67.43121 1.000 77.54291  ? 502 LYS B C   1 
ATOM   7776 O  O   . LYS B 1 502 ? 60.51709  10.75225  -67.91496 1.000 82.75707  ? 502 LYS B O   1 
ATOM   7777 C  CB  . LYS B 1 502 ? 62.12932  8.08121   -68.95208 1.000 76.93468  ? 502 LYS B CB  1 
ATOM   7778 C  CG  . LYS B 1 502 ? 62.85430  7.97478   -70.28378 1.000 68.20068  ? 502 LYS B CG  1 
ATOM   7779 C  CD  . LYS B 1 502 ? 62.51527  6.67442   -70.99563 1.000 73.93248  ? 502 LYS B CD  1 
ATOM   7780 C  CE  . LYS B 1 502 ? 63.17940  6.60263   -72.35987 1.000 71.86173  ? 502 LYS B CE  1 
ATOM   7781 N  NZ  . LYS B 1 502 ? 62.80372  5.36887   -73.10244 1.000 80.71336  ? 502 LYS B NZ  1 
ATOM   7782 N  N   . TRP B 1 503 ? 60.93579  9.28478   -66.26136 1.000 69.99645  ? 503 TRP B N   1 
ATOM   7783 C  CA  . TRP B 1 503 ? 59.83988  9.78276   -65.43924 1.000 71.37236  ? 503 TRP B CA  1 
ATOM   7784 C  C   . TRP B 1 503 ? 60.12366  11.19565  -64.94054 1.000 72.65026  ? 503 TRP B C   1 
ATOM   7785 O  O   . TRP B 1 503 ? 59.23379  12.05247  -64.93207 1.000 74.79320  ? 503 TRP B O   1 
ATOM   7786 C  CB  . TRP B 1 503 ? 59.59634  8.83411   -64.26504 1.000 68.71403  ? 503 TRP B CB  1 
ATOM   7787 C  CG  . TRP B 1 503 ? 58.58888  9.35221   -63.28430 1.000 59.18474  ? 503 TRP B CG  1 
ATOM   7788 C  CD1 . TRP B 1 503 ? 57.23102  9.25336   -63.37486 1.000 63.74031  ? 503 TRP B CD1 1 
ATOM   7789 C  CD2 . TRP B 1 503 ? 58.85928  10.05165  -62.06272 1.000 65.14525  ? 503 TRP B CD2 1 
ATOM   7790 N  NE1 . TRP B 1 503 ? 56.63971  9.84987   -62.28749 1.000 68.87559  ? 503 TRP B NE1 1 
ATOM   7791 C  CE2 . TRP B 1 503 ? 57.61731  10.34828  -61.46746 1.000 70.74523  ? 503 TRP B CE2 1 
ATOM   7792 C  CE3 . TRP B 1 503 ? 60.03102  10.45778  -61.41596 1.000 71.36527  ? 503 TRP B CE3 1 
ATOM   7793 C  CZ2 . TRP B 1 503 ? 57.51324  11.03188  -60.25706 1.000 77.21802  ? 503 TRP B CZ2 1 
ATOM   7794 C  CZ3 . TRP B 1 503 ? 59.92508  11.13785  -60.21399 1.000 80.15294  ? 503 TRP B CZ3 1 
ATOM   7795 C  CH2 . TRP B 1 503 ? 58.67547  11.41682  -59.64754 1.000 81.80353  ? 503 TRP B CH2 1 
ATOM   7796 N  N   . THR B 1 504 ? 61.36259  11.45046  -64.50800 1.000 75.86328  ? 504 THR B N   1 
ATOM   7797 C  CA  . THR B 1 504 ? 61.72073  12.75244  -63.94751 1.000 72.94683  ? 504 THR B CA  1 
ATOM   7798 C  C   . THR B 1 504 ? 61.48074  13.87804  -64.94538 1.000 75.43249  ? 504 THR B C   1 
ATOM   7799 O  O   . THR B 1 504 ? 60.88355  14.90658  -64.60792 1.000 77.04478  ? 504 THR B O   1 
ATOM   7800 C  CB  . THR B 1 504 ? 63.18615  12.75188  -63.50033 1.000 54.02660  ? 504 THR B CB  1 
ATOM   7801 O  OG1 . THR B 1 504 ? 63.36025  11.82922  -62.41675 1.000 69.45676  ? 504 THR B OG1 1 
ATOM   7802 C  CG2 . THR B 1 504 ? 63.60200  14.14145  -63.04113 1.000 60.00846  ? 504 THR B CG2 1 
ATOM   7803 N  N   . THR B 1 505 ? 61.93987  13.69535  -66.18664 1.000 69.59297  ? 505 THR B N   1 
ATOM   7804 C  CA  . THR B 1 505 ? 61.74639  14.71749  -67.21244 1.000 73.83799  ? 505 THR B CA  1 
ATOM   7805 C  C   . THR B 1 505 ? 60.26462  14.97474  -67.46020 1.000 77.66709  ? 505 THR B C   1 
ATOM   7806 O  O   . THR B 1 505 ? 59.83770  16.12954  -67.58161 1.000 79.19115  ? 505 THR B O   1 
ATOM   7807 C  CB  . THR B 1 505 ? 62.44575  14.29744  -68.50636 1.000 77.15417  ? 505 THR B CB  1 
ATOM   7808 O  OG1 . THR B 1 505 ? 63.84260  14.10066  -68.25237 1.000 75.55962  ? 505 THR B OG1 1 
ATOM   7809 C  CG2 . THR B 1 505 ? 62.26923  15.36012  -69.57990 1.000 76.47247  ? 505 THR B CG2 1 
ATOM   7810 N  N   . GLN B 1 506 ? 59.46204  13.91095  -67.52140 1.000 74.06906  ? 506 GLN B N   1 
ATOM   7811 C  CA  . GLN B 1 506 ? 58.03055  14.07503  -67.74815 1.000 76.71103  ? 506 GLN B CA  1 
ATOM   7812 C  C   . GLN B 1 506 ? 57.32752  14.66162  -66.53117 1.000 70.93291  ? 506 GLN B C   1 
ATOM   7813 O  O   . GLN B 1 506 ? 56.33568  15.38455  -66.67915 1.000 69.34298  ? 506 GLN B O   1 
ATOM   7814 C  CB  . GLN B 1 506 ? 57.40852  12.72844  -68.12172 1.000 78.61219  ? 506 GLN B CB  1 
ATOM   7815 C  CG  . GLN B 1 506 ? 57.83505  12.20578  -69.48252 1.000 81.33481  ? 506 GLN B CG  1 
ATOM   7816 C  CD  . GLN B 1 506 ? 56.85974  12.58235  -70.57697 1.000 84.46459  ? 506 GLN B CD  1 
ATOM   7817 O  OE1 . GLN B 1 506 ? 55.68546  12.21787  -70.52541 1.000 90.06786  ? 506 GLN B OE1 1 
ATOM   7818 N  NE2 . GLN B 1 506 ? 57.33951  13.31592  -71.57490 1.000 91.78572  ? 506 GLN B NE2 1 
ATOM   7819 N  N   . TRP B 1 507 ? 57.81826  14.35810  -65.32830 1.000 74.35256  ? 507 TRP B N   1 
ATOM   7820 C  CA  . TRP B 1 507 ? 57.19858  14.87662  -64.11343 1.000 81.38178  ? 507 TRP B CA  1 
ATOM   7821 C  C   . TRP B 1 507 ? 57.36729  16.38716  -64.00689 1.000 76.93708  ? 507 TRP B C   1 
ATOM   7822 O  O   . TRP B 1 507 ? 56.41318  17.10787  -63.69222 1.000 65.99163  ? 507 TRP B O   1 
ATOM   7823 C  CB  . TRP B 1 507 ? 57.78819  14.17896  -62.88541 1.000 66.42659  ? 507 TRP B CB  1 
ATOM   7824 C  CG  . TRP B 1 507 ? 57.35142  14.79463  -61.58848 1.000 84.47968  ? 507 TRP B CG  1 
ATOM   7825 C  CD1 . TRP B 1 507 ? 57.96120  15.81666  -60.92393 1.000 79.68436  ? 507 TRP B CD1 1 
ATOM   7826 C  CD2 . TRP B 1 507 ? 56.20663  14.43267  -60.80303 1.000 81.87548  ? 507 TRP B CD2 1 
ATOM   7827 N  NE1 . TRP B 1 507 ? 57.26992  16.11427  -59.77734 1.000 70.82105  ? 507 TRP B NE1 1 
ATOM   7828 C  CE2 . TRP B 1 507 ? 56.18931  15.27923  -59.67765 1.000 74.39984  ? 507 TRP B CE2 1 
ATOM   7829 C  CE3 . TRP B 1 507 ? 55.19701  13.47613  -60.94180 1.000 74.40041  ? 507 TRP B CE3 1 
ATOM   7830 C  CZ2 . TRP B 1 507 ? 55.20362  15.19895  -58.69672 1.000 78.83642  ? 507 TRP B CZ2 1 
ATOM   7831 C  CZ3 . TRP B 1 507 ? 54.21970  13.39707  -59.96613 1.000 73.64578  ? 507 TRP B CZ3 1 
ATOM   7832 C  CH2 . TRP B 1 507 ? 54.22968  14.25358  -58.85848 1.000 82.76580  ? 507 TRP B CH2 1 
ATOM   7833 N  N   . ASP B 1 508 ? 58.58131  16.88391  -64.25429 1.000 64.83357  ? 508 ASP B N   1 
ATOM   7834 C  CA  . ASP B 1 508 ? 58.82701  18.31712  -64.14245 1.000 69.33132  ? 508 ASP B CA  1 
ATOM   7835 C  C   . ASP B 1 508 ? 58.05979  19.10778  -65.19447 1.000 76.14280  ? 508 ASP B C   1 
ATOM   7836 O  O   . ASP B 1 508 ? 57.61510  20.22767  -64.91942 1.000 81.25583  ? 508 ASP B O   1 
ATOM   7837 C  CB  . ASP B 1 508 ? 60.32506  18.59824  -64.23393 1.000 74.97585  ? 508 ASP B CB  1 
ATOM   7838 C  CG  . ASP B 1 508 ? 61.09041  18.03880  -63.05178 1.000 79.33145  ? 508 ASP B CG  1 
ATOM   7839 O  OD1 . ASP B 1 508 ? 60.57255  18.12190  -61.91646 1.000 83.07103  ? 508 ASP B OD1 1 
ATOM   7840 O  OD2 . ASP B 1 508 ? 62.20122  17.50780  -63.25734 1.000 79.35350  ? 508 ASP B OD2 1 
ATOM   7841 N  N   . LYS B 1 509 ? 57.89436  18.55372  -66.39804 1.000 69.84093  ? 509 LYS B N   1 
ATOM   7842 C  CA  . LYS B 1 509 ? 57.05394  19.22184  -67.38545 1.000 70.52321  ? 509 LYS B CA  1 
ATOM   7843 C  C   . LYS B 1 509 ? 55.59599  19.23328  -66.94775 1.000 73.12824  ? 509 LYS B C   1 
ATOM   7844 O  O   . LYS B 1 509 ? 54.84607  20.14806  -67.30754 1.000 78.37706  ? 509 LYS B O   1 
ATOM   7845 C  CB  . LYS B 1 509 ? 57.19173  18.56042  -68.75639 1.000 59.91822  ? 509 LYS B CB  1 
ATOM   7846 C  CG  . LYS B 1 509 ? 56.56568  19.38884  -69.86942 1.000 82.76086  ? 509 LYS B CG  1 
ATOM   7847 C  CD  . LYS B 1 509 ? 56.71436  18.76219  -71.24374 1.000 76.32592  ? 509 LYS B CD  1 
ATOM   7848 C  CE  . LYS B 1 509 ? 56.21828  19.73180  -72.31058 1.000 87.65240  ? 509 LYS B CE  1 
ATOM   7849 N  NZ  . LYS B 1 509 ? 56.11297  19.11715  -73.66306 1.000 99.67545  ? 509 LYS B NZ  1 
ATOM   7850 N  N   . PHE B 1 510 ? 55.17698  18.22565  -66.18071 1.000 74.42745  ? 510 PHE B N   1 
ATOM   7851 C  CA  . PHE B 1 510 ? 53.82656  18.21948  -65.62890 1.000 71.60274  ? 510 PHE B CA  1 
ATOM   7852 C  C   . PHE B 1 510 ? 53.65344  19.31185  -64.57953 1.000 65.63735  ? 510 PHE B C   1 
ATOM   7853 O  O   . PHE B 1 510 ? 52.61883  19.98645  -64.54581 1.000 63.36654  ? 510 PHE B O   1 
ATOM   7854 C  CB  . PHE B 1 510 ? 53.51484  16.83758  -65.05018 1.000 73.47318  ? 510 PHE B CB  1 
ATOM   7855 C  CG  . PHE B 1 510 ? 52.49216  16.84518  -63.94805 1.000 62.63295  ? 510 PHE B CG  1 
ATOM   7856 C  CD1 . PHE B 1 510 ? 51.15258  17.07069  -64.22274 1.000 59.39324  ? 510 PHE B CD1 1 
ATOM   7857 C  CD2 . PHE B 1 510 ? 52.86829  16.59404  -62.63793 1.000 59.46525  ? 510 PHE B CD2 1 
ATOM   7858 C  CE1 . PHE B 1 510 ? 50.21266  17.06612  -63.20918 1.000 69.37214  ? 510 PHE B CE1 1 
ATOM   7859 C  CE2 . PHE B 1 510 ? 51.93384  16.58777  -61.62099 1.000 61.01475  ? 510 PHE B CE2 1 
ATOM   7860 C  CZ  . PHE B 1 510 ? 50.60450  16.82409  -61.90710 1.000 63.86657  ? 510 PHE B CZ  1 
ATOM   7861 N  N   . VAL B 1 511 ? 54.65507  19.50175  -63.71552 1.000 69.09314  ? 511 VAL B N   1 
ATOM   7862 C  CA  . VAL B 1 511 ? 54.57632  20.55051  -62.70077 1.000 64.99223  ? 511 VAL B CA  1 
ATOM   7863 C  C   . VAL B 1 511 ? 54.53788  21.92433  -63.35972 1.000 66.47884  ? 511 VAL B C   1 
ATOM   7864 O  O   . VAL B 1 511 ? 53.73247  22.78760  -62.99240 1.000 62.36532  ? 511 VAL B O   1 
ATOM   7865 C  CB  . VAL B 1 511 ? 55.75141  20.43511  -61.71256 1.000 51.14247  ? 511 VAL B CB  1 
ATOM   7866 C  CG1 . VAL B 1 511 ? 55.61706  21.47468  -60.61199 1.000 69.61931  ? 511 VAL B CG1 1 
ATOM   7867 C  CG2 . VAL B 1 511 ? 55.81884  19.03935  -61.11827 1.000 62.19594  ? 511 VAL B CG2 1 
ATOM   7868 N  N   . LYS B 1 512 ? 55.41470  22.14814  -64.34112 1.000 60.18527  ? 512 LYS B N   1 
ATOM   7869 C  CA  . LYS B 1 512 ? 55.48493  23.45144  -64.99656 1.000 62.85502  ? 512 LYS B CA  1 
ATOM   7870 C  C   . LYS B 1 512 ? 54.17155  23.79687  -65.68805 1.000 65.70866  ? 512 LYS B C   1 
ATOM   7871 O  O   . LYS B 1 512 ? 53.63606  24.89686  -65.51404 1.000 78.26561  ? 512 LYS B O   1 
ATOM   7872 C  CB  . LYS B 1 512 ? 56.64048  23.47068  -65.99721 1.000 63.26194  ? 512 LYS B CB  1 
ATOM   7873 C  CG  . LYS B 1 512 ? 56.72364  24.74339  -66.82262 1.000 83.93437  ? 512 LYS B CG  1 
ATOM   7874 C  CD  . LYS B 1 512 ? 57.89195  24.69880  -67.79385 1.000 81.71790  ? 512 LYS B CD  1 
ATOM   7875 C  CE  . LYS B 1 512 ? 57.98066  25.98232  -68.60307 1.000 85.99520  ? 512 LYS B CE  1 
ATOM   7876 N  NZ  . LYS B 1 512 ? 59.13408  25.97295  -69.54434 1.000 94.16810  ? 512 LYS B NZ  1 
ATOM   7877 N  N   . THR B 1 513 ? 53.63591  22.86355  -66.47884 1.000 65.84993  ? 513 THR B N   1 
ATOM   7878 C  CA  . THR B 1 513 ? 52.42147  23.14626  -67.23742 1.000 70.54898  ? 513 THR B CA  1 
ATOM   7879 C  C   . THR B 1 513 ? 51.21039  23.29244  -66.32196 1.000 69.69746  ? 513 THR B C   1 
ATOM   7880 O  O   . THR B 1 513 ? 50.33230  24.12535  -66.57630 1.000 72.54200  ? 513 THR B O   1 
ATOM   7881 C  CB  . THR B 1 513 ? 52.18547  22.04972  -68.27654 1.000 72.66134  ? 513 THR B CB  1 
ATOM   7882 O  OG1 . THR B 1 513 ? 53.38599  21.84224  -69.03025 1.000 66.97597  ? 513 THR B OG1 1 
ATOM   7883 C  CG2 . THR B 1 513 ? 51.06840  22.45185  -69.22708 1.000 71.68122  ? 513 THR B CG2 1 
ATOM   7884 N  N   . SER B 1 514 ? 51.14052  22.49254  -65.25582 1.000 74.75628  ? 514 SER B N   1 
ATOM   7885 C  CA  . SER B 1 514 ? 50.00671  22.58251  -64.33929 1.000 69.41074  ? 514 SER B CA  1 
ATOM   7886 C  C   . SER B 1 514 ? 50.02956  23.89297  -63.56039 1.000 77.33539  ? 514 SER B C   1 
ATOM   7887 O  O   . SER B 1 514 ? 48.99823  24.56124  -63.42026 1.000 78.07158  ? 514 SER B O   1 
ATOM   7888 C  CB  . SER B 1 514 ? 50.00037  21.38719  -63.38623 1.000 66.11531  ? 514 SER B CB  1 
ATOM   7889 O  OG  . SER B 1 514 ? 49.83470  20.16432  -64.08347 1.000 91.17649  ? 514 SER B OG  1 
ATOM   7890 N  N   . VAL B 1 515 ? 51.19982  24.27351  -63.03960 1.000 76.26939  ? 515 VAL B N   1 
ATOM   7891 C  CA  . VAL B 1 515 ? 51.32092  25.53975  -62.31991 1.000 71.04563  ? 515 VAL B CA  1 
ATOM   7892 C  C   . VAL B 1 515 ? 51.07304  26.71376  -63.25918 1.000 63.06220  ? 515 VAL B C   1 
ATOM   7893 O  O   . VAL B 1 515 ? 50.44303  27.70832  -62.88077 1.000 71.96389  ? 515 VAL B O   1 
ATOM   7894 C  CB  . VAL B 1 515 ? 52.69575  25.63801  -61.63254 1.000 54.74918  ? 515 VAL B CB  1 
ATOM   7895 C  CG1 . VAL B 1 515 ? 52.90721  27.02517  -61.05159 1.000 75.17884  ? 515 VAL B CG1 1 
ATOM   7896 C  CG2 . VAL B 1 515 ? 52.80222  24.59724  -60.54003 1.000 64.05605  ? 515 VAL B CG2 1 
ATOM   7897 N  N   . GLU B 1 516 ? 51.55728  26.61632  -64.49972 1.000 64.43270  ? 516 GLU B N   1 
ATOM   7898 C  CA  . GLU B 1 516 ? 51.33540  27.68784  -65.46506 1.000 63.17268  ? 516 GLU B CA  1 
ATOM   7899 C  C   . GLU B 1 516 ? 49.85591  27.88893  -65.76128 1.000 65.58451  ? 516 GLU B C   1 
ATOM   7900 O  O   . GLU B 1 516 ? 49.42923  29.01360  -66.04654 1.000 73.44493  ? 516 GLU B O   1 
ATOM   7901 C  CB  . GLU B 1 516 ? 52.09892  27.40428  -66.75877 1.000 69.36057  ? 516 GLU B CB  1 
ATOM   7902 C  CG  . GLU B 1 516 ? 53.54634  27.86266  -66.74495 1.000 71.72602  ? 516 GLU B CG  1 
ATOM   7903 C  CD  . GLU B 1 516 ? 54.12127  28.01359  -68.14098 1.000 92.20081  ? 516 GLU B CD  1 
ATOM   7904 O  OE1 . GLU B 1 516 ? 53.73475  27.23130  -69.03528 1.000 101.39776 ? 516 GLU B OE1 1 
ATOM   7905 O  OE2 . GLU B 1 516 ? 54.95296  28.92273  -68.34680 1.000 95.56289  ? 516 GLU B OE2 1 
ATOM   7906 N  N   . GLY B 1 517 ? 49.06128  26.82376  -65.70901 1.000 56.33215  ? 517 GLY B N   1 
ATOM   7907 C  CA  . GLY B 1 517 ? 47.64287  26.93869  -65.99191 1.000 59.35670  ? 517 GLY B CA  1 
ATOM   7908 C  C   . GLY B 1 517 ? 46.76317  27.31385  -64.82185 1.000 69.05847  ? 517 GLY B C   1 
ATOM   7909 O  O   . GLY B 1 517 ? 45.55937  27.51563  -65.00777 1.000 78.28950  ? 517 GLY B O   1 
ATOM   7910 N  N   . LEU B 1 518 ? 47.32628  27.40777  -63.61808 1.000 57.25536  ? 518 LEU B N   1 
ATOM   7911 C  CA  . LEU B 1 518 ? 46.57388  27.76843  -62.42207 1.000 67.36679  ? 518 LEU B CA  1 
ATOM   7912 C  C   . LEU B 1 518 ? 47.08596  29.04271  -61.77162 1.000 75.96576  ? 518 LEU B C   1 
ATOM   7913 O  O   . LEU B 1 518 ? 46.28651  29.90598  -61.38748 1.000 65.58005  ? 518 LEU B O   1 
ATOM   7914 C  CB  . LEU B 1 518 ? 46.62013  26.61108  -61.41157 1.000 76.73724  ? 518 LEU B CB  1 
ATOM   7915 C  CG  . LEU B 1 518 ? 46.05553  25.27126  -61.88543 1.000 78.56280  ? 518 LEU B CG  1 
ATOM   7916 C  CD1 . LEU B 1 518 ? 46.41889  24.16528  -60.90877 1.000 83.06955  ? 518 LEU B CD1 1 
ATOM   7917 C  CD2 . LEU B 1 518 ? 44.54718  25.35886  -62.06257 1.000 80.08871  ? 518 LEU B CD2 1 
ATOM   7918 N  N   . LYS B 1 519 ? 48.39841  29.17883  -61.63257 1.000 71.03242  ? 519 LYS B N   1 
ATOM   7919 C  CA  . LYS B 1 519 ? 48.97266  30.34373  -60.97601 1.000 68.55381  ? 519 LYS B CA  1 
ATOM   7920 C  C   . LYS B 1 519 ? 48.83379  31.58084  -61.86368 1.000 76.40762  ? 519 LYS B C   1 
ATOM   7921 O  O   . LYS B 1 519 ? 48.98119  31.49006  -63.08654 1.000 71.76589  ? 519 LYS B O   1 
ATOM   7922 C  CB  . LYS B 1 519 ? 50.44378  30.07962  -60.64987 1.000 64.38622  ? 519 LYS B CB  1 
ATOM   7923 C  CG  . LYS B 1 519 ? 51.28446  31.31175  -60.37315 1.000 71.25845  ? 519 LYS B CG  1 
ATOM   7924 C  CD  . LYS B 1 519 ? 52.73594  30.92633  -60.13511 1.000 82.41604  ? 519 LYS B CD  1 
ATOM   7925 C  CE  . LYS B 1 519 ? 53.68560  31.97813  -60.68012 1.000 88.52121  ? 519 LYS B CE  1 
ATOM   7926 N  NZ  . LYS B 1 519 ? 53.58405  32.08800  -62.16129 1.000 83.32174  ? 519 LYS B NZ  1 
ATOM   7927 N  N   . PRO B 1 520 ? 48.54250  32.74298  -61.28063 1.000 73.16816  ? 520 PRO B N   1 
ATOM   7928 C  CA  . PRO B 1 520 ? 48.47219  33.97568  -62.07070 1.000 73.55204  ? 520 PRO B CA  1 
ATOM   7929 C  C   . PRO B 1 520 ? 49.82682  34.36185  -62.64331 1.000 79.43851  ? 520 PRO B C   1 
ATOM   7930 O  O   . PRO B 1 520 ? 50.87902  33.86900  -62.23319 1.000 80.67119  ? 520 PRO B O   1 
ATOM   7931 C  CB  . PRO B 1 520 ? 47.99106  35.02082  -61.05859 1.000 72.31085  ? 520 PRO B CB  1 
ATOM   7932 C  CG  . PRO B 1 520 ? 47.32309  34.23992  -59.99176 1.000 68.02173  ? 520 PRO B CG  1 
ATOM   7933 C  CD  . PRO B 1 520 ? 48.09552  32.95776  -59.89376 1.000 75.60097  ? 520 PRO B CD  1 
ATOM   7934 N  N   . HIS B 1 521 ? 49.78351  35.27209  -63.60847 1.000 77.18822  ? 521 HIS B N   1 
ATOM   7935 C  CA  . HIS B 1 521 ? 50.98896  35.71729  -64.29359 1.000 78.33444  ? 521 HIS B CA  1 
ATOM   7936 C  C   . HIS B 1 521 ? 51.67107  36.83648  -63.51731 1.000 73.72789  ? 521 HIS B C   1 
ATOM   7937 O  O   . HIS B 1 521 ? 52.15327  37.80379  -64.10577 1.000 63.96654  ? 521 HIS B O   1 
ATOM   7938 C  CB  . HIS B 1 521 ? 50.65593  36.18164  -65.71386 1.000 83.53061  ? 521 HIS B CB  1 
ATOM   7939 C  CG  . HIS B 1 521 ? 50.13088  35.09667  -66.60368 1.000 95.05862  ? 521 HIS B CG  1 
ATOM   7940 N  ND1 . HIS B 1 521 ? 49.07348  34.28705  -66.25492 1.000 93.25801  ? 521 HIS B ND1 1 
ATOM   7941 C  CD2 . HIS B 1 521 ? 50.51383  34.69725  -67.83852 1.000 96.52903  ? 521 HIS B CD2 1 
ATOM   7942 C  CE1 . HIS B 1 521 ? 48.83324  33.43033  -67.23189 1.000 95.27325  ? 521 HIS B CE1 1 
ATOM   7943 N  NE2 . HIS B 1 521 ? 49.69388  33.65817  -68.20574 1.000 100.08154 ? 521 HIS B NE2 1 
HETATM 7944 C  C1  . NAG C 2 .   ? 49.60888  14.08772  -15.58196 1.000 88.00314  ? 601 NAG A C1  1 
HETATM 7945 C  C2  . NAG C 2 .   ? 49.52868  15.61031  -15.73318 1.000 98.30426  ? 601 NAG A C2  1 
HETATM 7946 C  C3  . NAG C 2 .   ? 50.87889  16.23696  -16.10109 1.000 97.42278  ? 601 NAG A C3  1 
HETATM 7947 C  C4  . NAG C 2 .   ? 52.08519  15.58049  -15.43442 1.000 90.37872  ? 601 NAG A C4  1 
HETATM 7948 C  C5  . NAG C 2 .   ? 51.94874  14.05586  -15.46182 1.000 96.21346  ? 601 NAG A C5  1 
HETATM 7949 C  C6  . NAG C 2 .   ? 53.09338  13.33016  -14.78615 1.000 97.77382  ? 601 NAG A C6  1 
HETATM 7950 C  C7  . NAG C 2 .   ? 47.33707  16.42579  -16.60565 1.000 86.01983  ? 601 NAG A C7  1 
HETATM 7951 C  C8  . NAG C 2 .   ? 46.84160  16.56331  -15.18758 1.000 83.72542  ? 601 NAG A C8  1 
HETATM 7952 N  N2  . NAG C 2 .   ? 48.58901  15.96380  -16.76368 1.000 82.45851  ? 601 NAG A N2  1 
HETATM 7953 O  O1  . NAG C 2 .   ? 48.47641  13.64060  -14.93813 1.000 101.38253 ? 601 NAG A O1  1 
HETATM 7954 O  O3  . NAG C 2 .   ? 50.81406  17.60691  -15.79141 1.000 99.02394  ? 601 NAG A O3  1 
HETATM 7955 O  O4  . NAG C 2 .   ? 53.21993  16.00689  -16.15450 1.000 72.82795  ? 601 NAG A O4  1 
HETATM 7956 O  O5  . NAG C 2 .   ? 50.73363  13.71863  -14.82698 1.000 108.41916 ? 601 NAG A O5  1 
HETATM 7957 O  O6  . NAG C 2 .   ? 52.92100  11.93433  -14.86408 1.000 80.29740  ? 601 NAG A O6  1 
HETATM 7958 O  O7  . NAG C 2 .   ? 46.62814  16.71856  -17.55997 1.000 85.28452  ? 601 NAG A O7  1 
HETATM 7959 C  C1  . NAG D 2 .   ? 4.40950   4.57661   -37.81257 1.000 94.02716  ? 602 NAG A C1  1 
HETATM 7960 C  C2  . NAG D 2 .   ? 3.04771   4.24765   -37.19236 1.000 94.03585  ? 602 NAG A C2  1 
HETATM 7961 C  C3  . NAG D 2 .   ? 3.02118   4.59672   -35.70772 1.000 86.99647  ? 602 NAG A C3  1 
HETATM 7962 C  C4  . NAG D 2 .   ? 4.25942   4.07634   -34.99545 1.000 79.75266  ? 602 NAG A C4  1 
HETATM 7963 C  C5  . NAG D 2 .   ? 5.53068   4.49792   -35.74740 1.000 82.20771  ? 602 NAG A C5  1 
HETATM 7964 C  C6  . NAG D 2 .   ? 6.82510   4.00984   -35.13035 1.000 72.80410  ? 602 NAG A C6  1 
HETATM 7965 C  C7  . NAG D 2 .   ? 1.21604   4.48498   -38.83658 1.000 90.74748  ? 602 NAG A C7  1 
HETATM 7966 C  C8  . NAG D 2 .   ? 0.17356   5.46710   -39.30906 1.000 79.41365  ? 602 NAG A C8  1 
HETATM 7967 N  N2  . NAG D 2 .   ? 1.98979   4.96182   -37.85067 1.000 92.70016  ? 602 NAG A N2  1 
HETATM 7968 O  O1  . NAG D 2 .   ? 4.44038   4.02065   -39.06718 1.000 97.10964  ? 602 NAG A O1  1 
HETATM 7969 O  O3  . NAG D 2 .   ? 1.84263   4.08597   -35.13321 1.000 84.14260  ? 602 NAG A O3  1 
HETATM 7970 O  O4  . NAG D 2 .   ? 4.18481   4.65610   -33.72036 1.000 71.03651  ? 602 NAG A O4  1 
HETATM 7971 O  O5  . NAG D 2 .   ? 5.44873   4.00144   -37.06461 1.000 89.12378  ? 602 NAG A O5  1 
HETATM 7972 O  O6  . NAG D 2 .   ? 7.93456   4.59131   -35.77583 1.000 67.75463  ? 602 NAG A O6  1 
HETATM 7973 O  O7  . NAG D 2 .   ? 1.32748   3.36644   -39.32002 1.000 84.77064  ? 602 NAG A O7  1 
HETATM 7974 C  C1  . NAG E 2 .   ? 8.87716   -2.04860  -10.42178 1.000 109.48163 ? 603 NAG A C1  1 
HETATM 7975 C  C2  . NAG E 2 .   ? 7.72151   -2.55693  -9.53603  1.000 87.40178  ? 603 NAG A C2  1 
HETATM 7976 C  C3  . NAG E 2 .   ? 7.94831   -2.10980  -8.10144  1.000 90.51525  ? 603 NAG A C3  1 
HETATM 7977 C  C4  . NAG E 2 .   ? 9.33055   -2.54416  -7.63622  1.000 88.49071  ? 603 NAG A C4  1 
HETATM 7978 C  C5  . NAG E 2 .   ? 10.39544  -1.84031  -8.48151  1.000 106.11875 ? 603 NAG A C5  1 
HETATM 7979 C  C6  . NAG E 2 .   ? 11.77203  -2.44045  -8.32148  1.000 83.77295  ? 603 NAG A C6  1 
HETATM 7980 C  C7  . NAG E 2 .   ? 5.53413   -2.52050  -10.72556 1.000 104.69589 ? 603 NAG A C7  1 
HETATM 7981 C  C8  . NAG E 2 .   ? 4.40598   -1.64408  -11.21766 1.000 102.25871 ? 603 NAG A C8  1 
HETATM 7982 N  N2  . NAG E 2 .   ? 6.53585   -1.92885  -10.05488 1.000 102.39924 ? 603 NAG A N2  1 
HETATM 7983 O  O3  . NAG E 2 .   ? 6.95617   -2.68440  -7.29760  1.000 96.75683  ? 603 NAG A O3  1 
HETATM 7984 O  O4  . NAG E 2 .   ? 9.48269   -2.26240  -6.26174  1.000 109.59641 ? 603 NAG A O4  1 
HETATM 7985 O  O5  . NAG E 2 .   ? 10.18787  -2.11338  -9.85810  1.000 117.19481 ? 603 NAG A O5  1 
HETATM 7986 O  O6  . NAG E 2 .   ? 12.39252  -2.44670  -9.59172  1.000 85.06805  ? 603 NAG A O6  1 
HETATM 7987 O  O7  . NAG E 2 .   ? 5.52709   -3.71893  -10.92833 1.000 86.77035  ? 603 NAG A O7  1 
HETATM 7988 ZN ZN  . ZN  F 3 .   ? 30.19049  5.58631   -25.11601 1.000 95.04485  ? 604 ZN  A ZN  1 
HETATM 7989 C  C1  . NAG G 2 .   ? 28.49969  22.94629  -45.20452 1.000 75.76306  ? 601 NAG B C1  1 
HETATM 7990 C  C2  . NAG G 2 .   ? 27.63471  24.14955  -45.59259 1.000 65.38756  ? 601 NAG B C2  1 
HETATM 7991 C  C3  . NAG G 2 .   ? 28.50605  25.19476  -46.34039 1.000 77.38485  ? 601 NAG B C3  1 
HETATM 7992 C  C4  . NAG G 2 .   ? 29.85532  25.45410  -45.64558 1.000 79.28047  ? 601 NAG B C4  1 
HETATM 7993 C  C5  . NAG G 2 .   ? 30.59770  24.12541  -45.46940 1.000 72.69581  ? 601 NAG B C5  1 
HETATM 7994 C  C6  . NAG G 2 .   ? 31.84758  24.18513  -44.60892 1.000 94.30822  ? 601 NAG B C6  1 
HETATM 7995 C  C7  . NAG G 2 .   ? 25.32103  24.15617  -46.56473 1.000 81.08206  ? 601 NAG B C7  1 
HETATM 7996 C  C8  . NAG G 2 .   ? 24.78514  25.06888  -45.50783 1.000 71.44369  ? 601 NAG B C8  1 
HETATM 7997 N  N2  . NAG G 2 .   ? 26.58541  23.74013  -46.48505 1.000 80.05035  ? 601 NAG B N2  1 
HETATM 7998 O  O1  . NAG G 2 .   ? 27.99327  22.56722  -43.98996 1.000 89.42595  ? 601 NAG B O1  1 
HETATM 7999 O  O3  . NAG G 2 .   ? 27.77286  26.40915  -46.45328 1.000 56.47428  ? 601 NAG B O3  1 
HETATM 8000 O  O4  . NAG G 2 .   ? 30.56146  26.37884  -46.43164 1.000 94.64848  ? 601 NAG B O4  1 
HETATM 8001 O  O5  . NAG G 2 .   ? 29.78106  23.25605  -44.70748 1.000 79.31178  ? 601 NAG B O5  1 
HETATM 8002 O  O6  . NAG G 2 .   ? 31.87695  22.97201  -43.88604 1.000 63.67321  ? 601 NAG B O6  1 
HETATM 8003 O  O7  . NAG G 2 .   ? 24.62402  23.78552  -47.49798 1.000 100.41407 ? 601 NAG B O7  1 
HETATM 8004 C  C1  . NAG H 2 .   ? 20.16701  -8.32541  -69.77464 1.000 96.69489  ? 602 NAG B C1  1 
HETATM 8005 C  C2  . NAG H 2 .   ? 18.92376  -9.23255  -69.93265 1.000 86.05982  ? 602 NAG B C2  1 
HETATM 8006 C  C3  . NAG H 2 .   ? 18.22176  -9.26871  -68.54896 1.000 81.08230  ? 602 NAG B C3  1 
HETATM 8007 C  C4  . NAG H 2 .   ? 19.08959  -9.14361  -67.28258 1.000 86.50170  ? 602 NAG B C4  1 
HETATM 8008 C  C5  . NAG H 2 .   ? 20.32418  -8.28212  -67.52375 1.000 76.49257  ? 602 NAG B C5  1 
HETATM 8009 C  C6  . NAG H 2 .   ? 21.39367  -8.27131  -66.45614 1.000 90.06685  ? 602 NAG B C6  1 
HETATM 8010 C  C7  . NAG H 2 .   ? 16.71554  -9.21420  -71.16637 1.000 94.12154  ? 602 NAG B C7  1 
HETATM 8011 C  C8  . NAG H 2 .   ? 15.91094  -8.42756  -72.17068 1.000 101.53884 ? 602 NAG B C8  1 
HETATM 8012 N  N2  . NAG H 2 .   ? 17.94945  -8.71286  -70.87073 1.000 90.17709  ? 602 NAG B N2  1 
HETATM 8013 O  O3  . NAG H 2 .   ? 17.47758  -10.45444 -68.45705 1.000 92.92356  ? 602 NAG B O3  1 
HETATM 8014 O  O4  . NAG H 2 .   ? 18.28712  -8.58939  -66.26509 1.000 92.43081  ? 602 NAG B O4  1 
HETATM 8015 O  O5  . NAG H 2 .   ? 20.87675  -8.83034  -68.67765 1.000 77.35300  ? 602 NAG B O5  1 
HETATM 8016 O  O6  . NAG H 2 .   ? 22.47675  -7.51015  -66.93884 1.000 71.66288  ? 602 NAG B O6  1 
HETATM 8017 O  O7  . NAG H 2 .   ? 16.22941  -10.23112 -70.69309 1.000 80.51208  ? 602 NAG B O7  1 
HETATM 8018 C  C1  . NAG I 2 .   ? 40.16071  -2.27365  -84.86490 1.000 92.35324  ? 603 NAG B C1  1 
HETATM 8019 C  C2  . NAG I 2 .   ? 39.77996  -1.72236  -86.23063 1.000 82.46616  ? 603 NAG B C2  1 
HETATM 8020 C  C3  . NAG I 2 .   ? 41.00096  -2.00395  -87.11216 1.000 80.79952  ? 603 NAG B C3  1 
HETATM 8021 C  C4  . NAG I 2 .   ? 42.31864  -1.59277  -86.43672 1.000 78.54437  ? 603 NAG B C4  1 
HETATM 8022 C  C5  . NAG I 2 .   ? 42.38952  -2.09574  -84.98347 1.000 83.39532  ? 603 NAG B C5  1 
HETATM 8023 C  C6  . NAG I 2 .   ? 43.62863  -1.70234  -84.21427 1.000 92.94478  ? 603 NAG B C6  1 
HETATM 8024 C  C7  . NAG I 2 .   ? 37.36980  -1.77260  -86.76807 1.000 84.94716  ? 603 NAG B C7  1 
HETATM 8025 C  C8  . NAG I 2 .   ? 36.26729  -2.60801  -87.37121 1.000 78.34347  ? 603 NAG B C8  1 
HETATM 8026 N  N2  . NAG I 2 .   ? 38.59125  -2.34318  -86.75509 1.000 87.22959  ? 603 NAG B N2  1 
HETATM 8027 O  O1  . NAG I 2 .   ? 39.20453  -1.55115  -84.22908 1.000 97.45785  ? 603 NAG B O1  1 
HETATM 8028 O  O3  . NAG I 2 .   ? 40.82061  -1.35643  -88.34408 1.000 90.15062  ? 603 NAG B O3  1 
HETATM 8029 O  O4  . NAG I 2 .   ? 43.36265  -2.13849  -87.20760 1.000 82.43866  ? 603 NAG B O4  1 
HETATM 8030 O  O5  . NAG I 2 .   ? 41.25407  -1.64422  -84.27226 1.000 96.80464  ? 603 NAG B O5  1 
HETATM 8031 O  O6  . NAG I 2 .   ? 43.65245  -2.44113  -83.01699 1.000 81.72176  ? 603 NAG B O6  1 
HETATM 8032 O  O7  . NAG I 2 .   ? 37.14558  -0.65519  -86.32629 1.000 76.76987  ? 603 NAG B O7  1 
HETATM 8033 ZN ZN  . ZN  J 3 .   ? 44.94872  -9.74824  -59.09398 1.000 96.55485  ? 604 ZN  B ZN  1 
HETATM 8034 O  O   . HOH K 4 .   ? 43.77695  -22.36659 -38.88904 1.000 52.98781  ? 701 HOH B O   1 
HETATM 8035 O  O   . HOH K 4 .   ? 41.85658  -11.14861 -62.33638 1.000 49.68512  ? 702 HOH B O   1 
HETATM 8036 O  O   . HOH K 4 .   ? 33.26523  -1.76161  -44.13394 1.000 59.95348  ? 703 HOH B O   1 
# 
