data_9NOM
# 
_entry.id   9NOM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.404 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NOM         pdb_00009nom 10.2210/pdb9nom/pdb 
WWPDB D_1000293315 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-06-18 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NOM 
_pdbx_database_status.recvd_initial_deposition_date   2025-03-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        'Nocardichelin Pathway' 
_pdbx_database_related.db_id          9NIJ 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              amgulick@buffalo.edu 
_pdbx_contact_author.name_first         Andrew 
_pdbx_contact_author.name_last          Gulick 
_pdbx_contact_author.name_mi            M 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4238-7453 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fisk, M.B.'   1 0009-0005-4260-7710 
'Gulick, A.M.' 2 0000-0003-4238-7453 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Chem.Biol.' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1554-8937 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acschembio.5c00286 
_citation.pdbx_database_id_PubMed   40479602 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fisk, M.B.'          1 ?                   
primary 'Barrera Ramirez, J.' 2 ?                   
primary 'Merrick, C.E.'       3 0009-0009-5728-4749 
primary 'Wencewicz, T.A.'     4 0000-0002-5839-6672 
primary 'Gulick, A.M.'        5 0000-0003-4238-7453 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'NcdF, a non-ribosomal independent siderophore synthetase' 68751.586 2 6.3.2.- ? ? 
'N-terminal Gly His remain following cleavage of Histidine tag' 
2 non-polymer syn 'MALONATE ION'                                             102.046   2 ?       ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GHMSIDIRGATEVPAPACSYRQVYNTRLARKILAEFCHERLVRPTELSPGRYVVHSDDRETEYRFRAEILSLDSWCIDAA
SLRRVRKGEELRIDAIDLIVDMSGSLGIPVDALPEYLEEFTNTASISMDRPDTRRIPAAELAVADFQTIEKTMTEGHPCL
VANAGRLGFSADDIERYAPESGGRFALEWVAVLRVNTDFAAMSGTEYDTLIRDELGADTLARFDRVLTGRGLDPASYYYM
PVHPWQWAEKIARIYAVDIAEGRIVPVGAGPDRYQPQQSIRTVFNVSVPTRHYVKTALSIVNMGFTRGMSADYMRTTPLI
NDWVRSRVHGDPYLASIGFEMIYEVAAIGYRNTTLTAITRPGSEYRKLLSALWRESPVSRVAEHEQLTTMAALLHIDHNG
IPLAGEFIQKSGLAAQEWLARYLRAYLHPIIYLLYRYEFKFSPHGENLILVLDGGAPVRAVLKDIGEEICIFDAPDDIPE
SCRRAVTEEADEIRNLGVLSDVFDDFLRHFALLLHESGLLTDGEFWATVAHSVAEFQARHPDLADRFDQWDLFAPTFPAI
HMNRLQLSNNRRMVNLGDSYSTLVDNEHALVNPIAGHRGAVTTTSGAEVHAA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GHMSIDIRGATEVPAPACSYRQVYNTRLARKILAEFCHERLVRPTELSPGRYVVHSDDRETEYRFRAEILSLDSWCIDAA
SLRRVRKGEELRIDAIDLIVDMSGSLGIPVDALPEYLEEFTNTASISMDRPDTRRIPAAELAVADFQTIEKTMTEGHPCL
VANAGRLGFSADDIERYAPESGGRFALEWVAVLRVNTDFAAMSGTEYDTLIRDELGADTLARFDRVLTGRGLDPASYYYM
PVHPWQWAEKIARIYAVDIAEGRIVPVGAGPDRYQPQQSIRTVFNVSVPTRHYVKTALSIVNMGFTRGMSADYMRTTPLI
NDWVRSRVHGDPYLASIGFEMIYEVAAIGYRNTTLTAITRPGSEYRKLLSALWRESPVSRVAEHEQLTTMAALLHIDHNG
IPLAGEFIQKSGLAAQEWLARYLRAYLHPIIYLLYRYEFKFSPHGENLILVLDGGAPVRAVLKDIGEEICIFDAPDDIPE
SCRRAVTEEADEIRNLGVLSDVFDDFLRHFALLLHESGLLTDGEFWATVAHSVAEFQARHPDLADRFDQWDLFAPTFPAI
HMNRLQLSNNRRMVNLGDSYSTLVDNEHALVNPIAGHRGAVTTTSGAEVHAA
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'MALONATE ION' 
_pdbx_entity_nonpoly.comp_id     MLI 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   HIS n 
1 3   MET n 
1 4   SER n 
1 5   ILE n 
1 6   ASP n 
1 7   ILE n 
1 8   ARG n 
1 9   GLY n 
1 10  ALA n 
1 11  THR n 
1 12  GLU n 
1 13  VAL n 
1 14  PRO n 
1 15  ALA n 
1 16  PRO n 
1 17  ALA n 
1 18  CYS n 
1 19  SER n 
1 20  TYR n 
1 21  ARG n 
1 22  GLN n 
1 23  VAL n 
1 24  TYR n 
1 25  ASN n 
1 26  THR n 
1 27  ARG n 
1 28  LEU n 
1 29  ALA n 
1 30  ARG n 
1 31  LYS n 
1 32  ILE n 
1 33  LEU n 
1 34  ALA n 
1 35  GLU n 
1 36  PHE n 
1 37  CYS n 
1 38  HIS n 
1 39  GLU n 
1 40  ARG n 
1 41  LEU n 
1 42  VAL n 
1 43  ARG n 
1 44  PRO n 
1 45  THR n 
1 46  GLU n 
1 47  LEU n 
1 48  SER n 
1 49  PRO n 
1 50  GLY n 
1 51  ARG n 
1 52  TYR n 
1 53  VAL n 
1 54  VAL n 
1 55  HIS n 
1 56  SER n 
1 57  ASP n 
1 58  ASP n 
1 59  ARG n 
1 60  GLU n 
1 61  THR n 
1 62  GLU n 
1 63  TYR n 
1 64  ARG n 
1 65  PHE n 
1 66  ARG n 
1 67  ALA n 
1 68  GLU n 
1 69  ILE n 
1 70  LEU n 
1 71  SER n 
1 72  LEU n 
1 73  ASP n 
1 74  SER n 
1 75  TRP n 
1 76  CYS n 
1 77  ILE n 
1 78  ASP n 
1 79  ALA n 
1 80  ALA n 
1 81  SER n 
1 82  LEU n 
1 83  ARG n 
1 84  ARG n 
1 85  VAL n 
1 86  ARG n 
1 87  LYS n 
1 88  GLY n 
1 89  GLU n 
1 90  GLU n 
1 91  LEU n 
1 92  ARG n 
1 93  ILE n 
1 94  ASP n 
1 95  ALA n 
1 96  ILE n 
1 97  ASP n 
1 98  LEU n 
1 99  ILE n 
1 100 VAL n 
1 101 ASP n 
1 102 MET n 
1 103 SER n 
1 104 GLY n 
1 105 SER n 
1 106 LEU n 
1 107 GLY n 
1 108 ILE n 
1 109 PRO n 
1 110 VAL n 
1 111 ASP n 
1 112 ALA n 
1 113 LEU n 
1 114 PRO n 
1 115 GLU n 
1 116 TYR n 
1 117 LEU n 
1 118 GLU n 
1 119 GLU n 
1 120 PHE n 
1 121 THR n 
1 122 ASN n 
1 123 THR n 
1 124 ALA n 
1 125 SER n 
1 126 ILE n 
1 127 SER n 
1 128 MET n 
1 129 ASP n 
1 130 ARG n 
1 131 PRO n 
1 132 ASP n 
1 133 THR n 
1 134 ARG n 
1 135 ARG n 
1 136 ILE n 
1 137 PRO n 
1 138 ALA n 
1 139 ALA n 
1 140 GLU n 
1 141 LEU n 
1 142 ALA n 
1 143 VAL n 
1 144 ALA n 
1 145 ASP n 
1 146 PHE n 
1 147 GLN n 
1 148 THR n 
1 149 ILE n 
1 150 GLU n 
1 151 LYS n 
1 152 THR n 
1 153 MET n 
1 154 THR n 
1 155 GLU n 
1 156 GLY n 
1 157 HIS n 
1 158 PRO n 
1 159 CYS n 
1 160 LEU n 
1 161 VAL n 
1 162 ALA n 
1 163 ASN n 
1 164 ALA n 
1 165 GLY n 
1 166 ARG n 
1 167 LEU n 
1 168 GLY n 
1 169 PHE n 
1 170 SER n 
1 171 ALA n 
1 172 ASP n 
1 173 ASP n 
1 174 ILE n 
1 175 GLU n 
1 176 ARG n 
1 177 TYR n 
1 178 ALA n 
1 179 PRO n 
1 180 GLU n 
1 181 SER n 
1 182 GLY n 
1 183 GLY n 
1 184 ARG n 
1 185 PHE n 
1 186 ALA n 
1 187 LEU n 
1 188 GLU n 
1 189 TRP n 
1 190 VAL n 
1 191 ALA n 
1 192 VAL n 
1 193 LEU n 
1 194 ARG n 
1 195 VAL n 
1 196 ASN n 
1 197 THR n 
1 198 ASP n 
1 199 PHE n 
1 200 ALA n 
1 201 ALA n 
1 202 MET n 
1 203 SER n 
1 204 GLY n 
1 205 THR n 
1 206 GLU n 
1 207 TYR n 
1 208 ASP n 
1 209 THR n 
1 210 LEU n 
1 211 ILE n 
1 212 ARG n 
1 213 ASP n 
1 214 GLU n 
1 215 LEU n 
1 216 GLY n 
1 217 ALA n 
1 218 ASP n 
1 219 THR n 
1 220 LEU n 
1 221 ALA n 
1 222 ARG n 
1 223 PHE n 
1 224 ASP n 
1 225 ARG n 
1 226 VAL n 
1 227 LEU n 
1 228 THR n 
1 229 GLY n 
1 230 ARG n 
1 231 GLY n 
1 232 LEU n 
1 233 ASP n 
1 234 PRO n 
1 235 ALA n 
1 236 SER n 
1 237 TYR n 
1 238 TYR n 
1 239 TYR n 
1 240 MET n 
1 241 PRO n 
1 242 VAL n 
1 243 HIS n 
1 244 PRO n 
1 245 TRP n 
1 246 GLN n 
1 247 TRP n 
1 248 ALA n 
1 249 GLU n 
1 250 LYS n 
1 251 ILE n 
1 252 ALA n 
1 253 ARG n 
1 254 ILE n 
1 255 TYR n 
1 256 ALA n 
1 257 VAL n 
1 258 ASP n 
1 259 ILE n 
1 260 ALA n 
1 261 GLU n 
1 262 GLY n 
1 263 ARG n 
1 264 ILE n 
1 265 VAL n 
1 266 PRO n 
1 267 VAL n 
1 268 GLY n 
1 269 ALA n 
1 270 GLY n 
1 271 PRO n 
1 272 ASP n 
1 273 ARG n 
1 274 TYR n 
1 275 GLN n 
1 276 PRO n 
1 277 GLN n 
1 278 GLN n 
1 279 SER n 
1 280 ILE n 
1 281 ARG n 
1 282 THR n 
1 283 VAL n 
1 284 PHE n 
1 285 ASN n 
1 286 VAL n 
1 287 SER n 
1 288 VAL n 
1 289 PRO n 
1 290 THR n 
1 291 ARG n 
1 292 HIS n 
1 293 TYR n 
1 294 VAL n 
1 295 LYS n 
1 296 THR n 
1 297 ALA n 
1 298 LEU n 
1 299 SER n 
1 300 ILE n 
1 301 VAL n 
1 302 ASN n 
1 303 MET n 
1 304 GLY n 
1 305 PHE n 
1 306 THR n 
1 307 ARG n 
1 308 GLY n 
1 309 MET n 
1 310 SER n 
1 311 ALA n 
1 312 ASP n 
1 313 TYR n 
1 314 MET n 
1 315 ARG n 
1 316 THR n 
1 317 THR n 
1 318 PRO n 
1 319 LEU n 
1 320 ILE n 
1 321 ASN n 
1 322 ASP n 
1 323 TRP n 
1 324 VAL n 
1 325 ARG n 
1 326 SER n 
1 327 ARG n 
1 328 VAL n 
1 329 HIS n 
1 330 GLY n 
1 331 ASP n 
1 332 PRO n 
1 333 TYR n 
1 334 LEU n 
1 335 ALA n 
1 336 SER n 
1 337 ILE n 
1 338 GLY n 
1 339 PHE n 
1 340 GLU n 
1 341 MET n 
1 342 ILE n 
1 343 TYR n 
1 344 GLU n 
1 345 VAL n 
1 346 ALA n 
1 347 ALA n 
1 348 ILE n 
1 349 GLY n 
1 350 TYR n 
1 351 ARG n 
1 352 ASN n 
1 353 THR n 
1 354 THR n 
1 355 LEU n 
1 356 THR n 
1 357 ALA n 
1 358 ILE n 
1 359 THR n 
1 360 ARG n 
1 361 PRO n 
1 362 GLY n 
1 363 SER n 
1 364 GLU n 
1 365 TYR n 
1 366 ARG n 
1 367 LYS n 
1 368 LEU n 
1 369 LEU n 
1 370 SER n 
1 371 ALA n 
1 372 LEU n 
1 373 TRP n 
1 374 ARG n 
1 375 GLU n 
1 376 SER n 
1 377 PRO n 
1 378 VAL n 
1 379 SER n 
1 380 ARG n 
1 381 VAL n 
1 382 ALA n 
1 383 GLU n 
1 384 HIS n 
1 385 GLU n 
1 386 GLN n 
1 387 LEU n 
1 388 THR n 
1 389 THR n 
1 390 MET n 
1 391 ALA n 
1 392 ALA n 
1 393 LEU n 
1 394 LEU n 
1 395 HIS n 
1 396 ILE n 
1 397 ASP n 
1 398 HIS n 
1 399 ASN n 
1 400 GLY n 
1 401 ILE n 
1 402 PRO n 
1 403 LEU n 
1 404 ALA n 
1 405 GLY n 
1 406 GLU n 
1 407 PHE n 
1 408 ILE n 
1 409 GLN n 
1 410 LYS n 
1 411 SER n 
1 412 GLY n 
1 413 LEU n 
1 414 ALA n 
1 415 ALA n 
1 416 GLN n 
1 417 GLU n 
1 418 TRP n 
1 419 LEU n 
1 420 ALA n 
1 421 ARG n 
1 422 TYR n 
1 423 LEU n 
1 424 ARG n 
1 425 ALA n 
1 426 TYR n 
1 427 LEU n 
1 428 HIS n 
1 429 PRO n 
1 430 ILE n 
1 431 ILE n 
1 432 TYR n 
1 433 LEU n 
1 434 LEU n 
1 435 TYR n 
1 436 ARG n 
1 437 TYR n 
1 438 GLU n 
1 439 PHE n 
1 440 LYS n 
1 441 PHE n 
1 442 SER n 
1 443 PRO n 
1 444 HIS n 
1 445 GLY n 
1 446 GLU n 
1 447 ASN n 
1 448 LEU n 
1 449 ILE n 
1 450 LEU n 
1 451 VAL n 
1 452 LEU n 
1 453 ASP n 
1 454 GLY n 
1 455 GLY n 
1 456 ALA n 
1 457 PRO n 
1 458 VAL n 
1 459 ARG n 
1 460 ALA n 
1 461 VAL n 
1 462 LEU n 
1 463 LYS n 
1 464 ASP n 
1 465 ILE n 
1 466 GLY n 
1 467 GLU n 
1 468 GLU n 
1 469 ILE n 
1 470 CYS n 
1 471 ILE n 
1 472 PHE n 
1 473 ASP n 
1 474 ALA n 
1 475 PRO n 
1 476 ASP n 
1 477 ASP n 
1 478 ILE n 
1 479 PRO n 
1 480 GLU n 
1 481 SER n 
1 482 CYS n 
1 483 ARG n 
1 484 ARG n 
1 485 ALA n 
1 486 VAL n 
1 487 THR n 
1 488 GLU n 
1 489 GLU n 
1 490 ALA n 
1 491 ASP n 
1 492 GLU n 
1 493 ILE n 
1 494 ARG n 
1 495 ASN n 
1 496 LEU n 
1 497 GLY n 
1 498 VAL n 
1 499 LEU n 
1 500 SER n 
1 501 ASP n 
1 502 VAL n 
1 503 PHE n 
1 504 ASP n 
1 505 ASP n 
1 506 PHE n 
1 507 LEU n 
1 508 ARG n 
1 509 HIS n 
1 510 PHE n 
1 511 ALA n 
1 512 LEU n 
1 513 LEU n 
1 514 LEU n 
1 515 HIS n 
1 516 GLU n 
1 517 SER n 
1 518 GLY n 
1 519 LEU n 
1 520 LEU n 
1 521 THR n 
1 522 ASP n 
1 523 GLY n 
1 524 GLU n 
1 525 PHE n 
1 526 TRP n 
1 527 ALA n 
1 528 THR n 
1 529 VAL n 
1 530 ALA n 
1 531 HIS n 
1 532 SER n 
1 533 VAL n 
1 534 ALA n 
1 535 GLU n 
1 536 PHE n 
1 537 GLN n 
1 538 ALA n 
1 539 ARG n 
1 540 HIS n 
1 541 PRO n 
1 542 ASP n 
1 543 LEU n 
1 544 ALA n 
1 545 ASP n 
1 546 ARG n 
1 547 PHE n 
1 548 ASP n 
1 549 GLN n 
1 550 TRP n 
1 551 ASP n 
1 552 LEU n 
1 553 PHE n 
1 554 ALA n 
1 555 PRO n 
1 556 THR n 
1 557 PHE n 
1 558 PRO n 
1 559 ALA n 
1 560 ILE n 
1 561 HIS n 
1 562 MET n 
1 563 ASN n 
1 564 ARG n 
1 565 LEU n 
1 566 GLN n 
1 567 LEU n 
1 568 SER n 
1 569 ASN n 
1 570 ASN n 
1 571 ARG n 
1 572 ARG n 
1 573 MET n 
1 574 VAL n 
1 575 ASN n 
1 576 LEU n 
1 577 GLY n 
1 578 ASP n 
1 579 SER n 
1 580 TYR n 
1 581 SER n 
1 582 THR n 
1 583 LEU n 
1 584 VAL n 
1 585 ASP n 
1 586 ASN n 
1 587 GLU n 
1 588 HIS n 
1 589 ALA n 
1 590 LEU n 
1 591 VAL n 
1 592 ASN n 
1 593 PRO n 
1 594 ILE n 
1 595 ALA n 
1 596 GLY n 
1 597 HIS n 
1 598 ARG n 
1 599 GLY n 
1 600 ALA n 
1 601 VAL n 
1 602 THR n 
1 603 THR n 
1 604 THR n 
1 605 SER n 
1 606 GLY n 
1 607 ALA n 
1 608 GLU n 
1 609 VAL n 
1 610 HIS n 
1 611 ALA n 
1 612 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   612 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ncdF 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Nocardia carnea NBRC 14403' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1206726 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'BL21(DE3)' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
MLI non-polymer         . 'MALONATE ION'  ? 'C3 H2 O4 -2'    102.046 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   0   ?   ?   ?   A . n 
A 1 2   HIS 2   1   ?   ?   ?   A . n 
A 1 3   MET 3   2   ?   ?   ?   A . n 
A 1 4   SER 4   3   ?   ?   ?   A . n 
A 1 5   ILE 5   4   ?   ?   ?   A . n 
A 1 6   ASP 6   5   ?   ?   ?   A . n 
A 1 7   ILE 7   6   ?   ?   ?   A . n 
A 1 8   ARG 8   7   ?   ?   ?   A . n 
A 1 9   GLY 9   8   ?   ?   ?   A . n 
A 1 10  ALA 10  9   ?   ?   ?   A . n 
A 1 11  THR 11  10  ?   ?   ?   A . n 
A 1 12  GLU 12  11  ?   ?   ?   A . n 
A 1 13  VAL 13  12  ?   ?   ?   A . n 
A 1 14  PRO 14  13  ?   ?   ?   A . n 
A 1 15  ALA 15  14  ?   ?   ?   A . n 
A 1 16  PRO 16  15  ?   ?   ?   A . n 
A 1 17  ALA 17  16  16  ALA ALA A . n 
A 1 18  CYS 18  17  17  CYS CYS A . n 
A 1 19  SER 19  18  18  SER SER A . n 
A 1 20  TYR 20  19  19  TYR TYR A . n 
A 1 21  ARG 21  20  20  ARG ARG A . n 
A 1 22  GLN 22  21  21  GLN GLN A . n 
A 1 23  VAL 23  22  22  VAL VAL A . n 
A 1 24  TYR 24  23  23  TYR TYR A . n 
A 1 25  ASN 25  24  24  ASN ASN A . n 
A 1 26  THR 26  25  25  THR THR A . n 
A 1 27  ARG 27  26  26  ARG ARG A . n 
A 1 28  LEU 28  27  27  LEU LEU A . n 
A 1 29  ALA 29  28  28  ALA ALA A . n 
A 1 30  ARG 30  29  29  ARG ARG A . n 
A 1 31  LYS 31  30  30  LYS LYS A . n 
A 1 32  ILE 32  31  31  ILE ILE A . n 
A 1 33  LEU 33  32  32  LEU LEU A . n 
A 1 34  ALA 34  33  33  ALA ALA A . n 
A 1 35  GLU 35  34  34  GLU GLU A . n 
A 1 36  PHE 36  35  35  PHE PHE A . n 
A 1 37  CYS 37  36  36  CYS CYS A . n 
A 1 38  HIS 38  37  37  HIS HIS A . n 
A 1 39  GLU 39  38  38  GLU GLU A . n 
A 1 40  ARG 40  39  39  ARG ARG A . n 
A 1 41  LEU 41  40  40  LEU LEU A . n 
A 1 42  VAL 42  41  41  VAL VAL A . n 
A 1 43  ARG 43  42  42  ARG ARG A . n 
A 1 44  PRO 44  43  43  PRO PRO A . n 
A 1 45  THR 45  44  44  THR THR A . n 
A 1 46  GLU 46  45  45  GLU GLU A . n 
A 1 47  LEU 47  46  46  LEU LEU A . n 
A 1 48  SER 48  47  47  SER SER A . n 
A 1 49  PRO 49  48  48  PRO PRO A . n 
A 1 50  GLY 50  49  49  GLY GLY A . n 
A 1 51  ARG 51  50  50  ARG ARG A . n 
A 1 52  TYR 52  51  51  TYR TYR A . n 
A 1 53  VAL 53  52  52  VAL VAL A . n 
A 1 54  VAL 54  53  53  VAL VAL A . n 
A 1 55  HIS 55  54  54  HIS HIS A . n 
A 1 56  SER 56  55  55  SER SER A . n 
A 1 57  ASP 57  56  56  ASP ASP A . n 
A 1 58  ASP 58  57  57  ASP ASP A . n 
A 1 59  ARG 59  58  58  ARG ARG A . n 
A 1 60  GLU 60  59  59  GLU GLU A . n 
A 1 61  THR 61  60  60  THR THR A . n 
A 1 62  GLU 62  61  61  GLU GLU A . n 
A 1 63  TYR 63  62  62  TYR TYR A . n 
A 1 64  ARG 64  63  63  ARG ARG A . n 
A 1 65  PHE 65  64  64  PHE PHE A . n 
A 1 66  ARG 66  65  65  ARG ARG A . n 
A 1 67  ALA 67  66  66  ALA ALA A . n 
A 1 68  GLU 68  67  67  GLU GLU A . n 
A 1 69  ILE 69  68  68  ILE ILE A . n 
A 1 70  LEU 70  69  69  LEU LEU A . n 
A 1 71  SER 71  70  70  SER SER A . n 
A 1 72  LEU 72  71  71  LEU LEU A . n 
A 1 73  ASP 73  72  72  ASP ASP A . n 
A 1 74  SER 74  73  73  SER SER A . n 
A 1 75  TRP 75  74  74  TRP TRP A . n 
A 1 76  CYS 76  75  75  CYS CYS A . n 
A 1 77  ILE 77  76  76  ILE ILE A . n 
A 1 78  ASP 78  77  77  ASP ASP A . n 
A 1 79  ALA 79  78  78  ALA ALA A . n 
A 1 80  ALA 80  79  79  ALA ALA A . n 
A 1 81  SER 81  80  80  SER SER A . n 
A 1 82  LEU 82  81  81  LEU LEU A . n 
A 1 83  ARG 83  82  82  ARG ARG A . n 
A 1 84  ARG 84  83  83  ARG ARG A . n 
A 1 85  VAL 85  84  84  VAL VAL A . n 
A 1 86  ARG 86  85  85  ARG ARG A . n 
A 1 87  LYS 87  86  86  LYS LYS A . n 
A 1 88  GLY 88  87  87  GLY GLY A . n 
A 1 89  GLU 89  88  88  GLU GLU A . n 
A 1 90  GLU 90  89  89  GLU GLU A . n 
A 1 91  LEU 91  90  90  LEU LEU A . n 
A 1 92  ARG 92  91  91  ARG ARG A . n 
A 1 93  ILE 93  92  92  ILE ILE A . n 
A 1 94  ASP 94  93  93  ASP ASP A . n 
A 1 95  ALA 95  94  94  ALA ALA A . n 
A 1 96  ILE 96  95  95  ILE ILE A . n 
A 1 97  ASP 97  96  96  ASP ASP A . n 
A 1 98  LEU 98  97  97  LEU LEU A . n 
A 1 99  ILE 99  98  98  ILE ILE A . n 
A 1 100 VAL 100 99  99  VAL VAL A . n 
A 1 101 ASP 101 100 100 ASP ASP A . n 
A 1 102 MET 102 101 101 MET MET A . n 
A 1 103 SER 103 102 102 SER SER A . n 
A 1 104 GLY 104 103 103 GLY GLY A . n 
A 1 105 SER 105 104 104 SER SER A . n 
A 1 106 LEU 106 105 105 LEU LEU A . n 
A 1 107 GLY 107 106 106 GLY GLY A . n 
A 1 108 ILE 108 107 107 ILE ILE A . n 
A 1 109 PRO 109 108 108 PRO PRO A . n 
A 1 110 VAL 110 109 109 VAL VAL A . n 
A 1 111 ASP 111 110 110 ASP ASP A . n 
A 1 112 ALA 112 111 111 ALA ALA A . n 
A 1 113 LEU 113 112 112 LEU LEU A . n 
A 1 114 PRO 114 113 113 PRO PRO A . n 
A 1 115 GLU 115 114 114 GLU GLU A . n 
A 1 116 TYR 116 115 115 TYR TYR A . n 
A 1 117 LEU 117 116 116 LEU LEU A . n 
A 1 118 GLU 118 117 117 GLU GLU A . n 
A 1 119 GLU 119 118 118 GLU GLU A . n 
A 1 120 PHE 120 119 119 PHE PHE A . n 
A 1 121 THR 121 120 120 THR THR A . n 
A 1 122 ASN 122 121 121 ASN ASN A . n 
A 1 123 THR 123 122 122 THR THR A . n 
A 1 124 ALA 124 123 123 ALA ALA A . n 
A 1 125 SER 125 124 124 SER SER A . n 
A 1 126 ILE 126 125 125 ILE ILE A . n 
A 1 127 SER 127 126 126 SER SER A . n 
A 1 128 MET 128 127 127 MET MET A . n 
A 1 129 ASP 129 128 128 ASP ASP A . n 
A 1 130 ARG 130 129 129 ARG ARG A . n 
A 1 131 PRO 131 130 130 PRO PRO A . n 
A 1 132 ASP 132 131 131 ASP ASP A . n 
A 1 133 THR 133 132 132 THR THR A . n 
A 1 134 ARG 134 133 133 ARG ARG A . n 
A 1 135 ARG 135 134 134 ARG ARG A . n 
A 1 136 ILE 136 135 135 ILE ILE A . n 
A 1 137 PRO 137 136 136 PRO PRO A . n 
A 1 138 ALA 138 137 137 ALA ALA A . n 
A 1 139 ALA 139 138 138 ALA ALA A . n 
A 1 140 GLU 140 139 139 GLU GLU A . n 
A 1 141 LEU 141 140 140 LEU LEU A . n 
A 1 142 ALA 142 141 141 ALA ALA A . n 
A 1 143 VAL 143 142 142 VAL VAL A . n 
A 1 144 ALA 144 143 143 ALA ALA A . n 
A 1 145 ASP 145 144 144 ASP ASP A . n 
A 1 146 PHE 146 145 145 PHE PHE A . n 
A 1 147 GLN 147 146 146 GLN GLN A . n 
A 1 148 THR 148 147 147 THR THR A . n 
A 1 149 ILE 149 148 148 ILE ILE A . n 
A 1 150 GLU 150 149 149 GLU GLU A . n 
A 1 151 LYS 151 150 150 LYS LYS A . n 
A 1 152 THR 152 151 151 THR THR A . n 
A 1 153 MET 153 152 152 MET MET A . n 
A 1 154 THR 154 153 153 THR THR A . n 
A 1 155 GLU 155 154 154 GLU GLU A . n 
A 1 156 GLY 156 155 155 GLY GLY A . n 
A 1 157 HIS 157 156 156 HIS HIS A . n 
A 1 158 PRO 158 157 157 PRO PRO A . n 
A 1 159 CYS 159 158 158 CYS CYS A . n 
A 1 160 LEU 160 159 159 LEU LEU A . n 
A 1 161 VAL 161 160 160 VAL VAL A . n 
A 1 162 ALA 162 161 161 ALA ALA A . n 
A 1 163 ASN 163 162 162 ASN ASN A . n 
A 1 164 ALA 164 163 163 ALA ALA A . n 
A 1 165 GLY 165 164 164 GLY GLY A . n 
A 1 166 ARG 166 165 165 ARG ARG A . n 
A 1 167 LEU 167 166 166 LEU LEU A . n 
A 1 168 GLY 168 167 167 GLY GLY A . n 
A 1 169 PHE 169 168 168 PHE PHE A . n 
A 1 170 SER 170 169 169 SER SER A . n 
A 1 171 ALA 171 170 170 ALA ALA A . n 
A 1 172 ASP 172 171 171 ASP ASP A . n 
A 1 173 ASP 173 172 172 ASP ASP A . n 
A 1 174 ILE 174 173 173 ILE ILE A . n 
A 1 175 GLU 175 174 174 GLU GLU A . n 
A 1 176 ARG 176 175 175 ARG ARG A . n 
A 1 177 TYR 177 176 176 TYR TYR A . n 
A 1 178 ALA 178 177 177 ALA ALA A . n 
A 1 179 PRO 179 178 178 PRO PRO A . n 
A 1 180 GLU 180 179 179 GLU GLU A . n 
A 1 181 SER 181 180 180 SER SER A . n 
A 1 182 GLY 182 181 181 GLY GLY A . n 
A 1 183 GLY 183 182 182 GLY GLY A . n 
A 1 184 ARG 184 183 183 ARG ARG A . n 
A 1 185 PHE 185 184 184 PHE PHE A . n 
A 1 186 ALA 186 185 185 ALA ALA A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 GLU 188 187 187 GLU GLU A . n 
A 1 189 TRP 189 188 188 TRP TRP A . n 
A 1 190 VAL 190 189 189 VAL VAL A . n 
A 1 191 ALA 191 190 190 ALA ALA A . n 
A 1 192 VAL 192 191 191 VAL VAL A . n 
A 1 193 LEU 193 192 192 LEU LEU A . n 
A 1 194 ARG 194 193 193 ARG ARG A . n 
A 1 195 VAL 195 194 194 VAL VAL A . n 
A 1 196 ASN 196 195 195 ASN ASN A . n 
A 1 197 THR 197 196 196 THR THR A . n 
A 1 198 ASP 198 197 197 ASP ASP A . n 
A 1 199 PHE 199 198 198 PHE PHE A . n 
A 1 200 ALA 200 199 199 ALA ALA A . n 
A 1 201 ALA 201 200 200 ALA ALA A . n 
A 1 202 MET 202 201 201 MET MET A . n 
A 1 203 SER 203 202 202 SER SER A . n 
A 1 204 GLY 204 203 203 GLY GLY A . n 
A 1 205 THR 205 204 204 THR THR A . n 
A 1 206 GLU 206 205 205 GLU GLU A . n 
A 1 207 TYR 207 206 206 TYR TYR A . n 
A 1 208 ASP 208 207 207 ASP ASP A . n 
A 1 209 THR 209 208 208 THR THR A . n 
A 1 210 LEU 210 209 209 LEU LEU A . n 
A 1 211 ILE 211 210 210 ILE ILE A . n 
A 1 212 ARG 212 211 211 ARG ARG A . n 
A 1 213 ASP 213 212 212 ASP ASP A . n 
A 1 214 GLU 214 213 213 GLU GLU A . n 
A 1 215 LEU 215 214 214 LEU LEU A . n 
A 1 216 GLY 216 215 215 GLY GLY A . n 
A 1 217 ALA 217 216 216 ALA ALA A . n 
A 1 218 ASP 218 217 217 ASP ASP A . n 
A 1 219 THR 219 218 218 THR THR A . n 
A 1 220 LEU 220 219 219 LEU LEU A . n 
A 1 221 ALA 221 220 220 ALA ALA A . n 
A 1 222 ARG 222 221 221 ARG ARG A . n 
A 1 223 PHE 223 222 222 PHE PHE A . n 
A 1 224 ASP 224 223 223 ASP ASP A . n 
A 1 225 ARG 225 224 224 ARG ARG A . n 
A 1 226 VAL 226 225 225 VAL VAL A . n 
A 1 227 LEU 227 226 226 LEU LEU A . n 
A 1 228 THR 228 227 227 THR THR A . n 
A 1 229 GLY 229 228 228 GLY GLY A . n 
A 1 230 ARG 230 229 229 ARG ARG A . n 
A 1 231 GLY 231 230 230 GLY GLY A . n 
A 1 232 LEU 232 231 231 LEU LEU A . n 
A 1 233 ASP 233 232 232 ASP ASP A . n 
A 1 234 PRO 234 233 233 PRO PRO A . n 
A 1 235 ALA 235 234 234 ALA ALA A . n 
A 1 236 SER 236 235 235 SER SER A . n 
A 1 237 TYR 237 236 236 TYR TYR A . n 
A 1 238 TYR 238 237 237 TYR TYR A . n 
A 1 239 TYR 239 238 238 TYR TYR A . n 
A 1 240 MET 240 239 239 MET MET A . n 
A 1 241 PRO 241 240 240 PRO PRO A . n 
A 1 242 VAL 242 241 241 VAL VAL A . n 
A 1 243 HIS 243 242 242 HIS HIS A . n 
A 1 244 PRO 244 243 243 PRO PRO A . n 
A 1 245 TRP 245 244 244 TRP TRP A . n 
A 1 246 GLN 246 245 245 GLN GLN A . n 
A 1 247 TRP 247 246 246 TRP TRP A . n 
A 1 248 ALA 248 247 247 ALA ALA A . n 
A 1 249 GLU 249 248 248 GLU GLU A . n 
A 1 250 LYS 250 249 249 LYS LYS A . n 
A 1 251 ILE 251 250 250 ILE ILE A . n 
A 1 252 ALA 252 251 251 ALA ALA A . n 
A 1 253 ARG 253 252 252 ARG ARG A . n 
A 1 254 ILE 254 253 253 ILE ILE A . n 
A 1 255 TYR 255 254 254 TYR TYR A . n 
A 1 256 ALA 256 255 255 ALA ALA A . n 
A 1 257 VAL 257 256 256 VAL VAL A . n 
A 1 258 ASP 258 257 257 ASP ASP A . n 
A 1 259 ILE 259 258 258 ILE ILE A . n 
A 1 260 ALA 260 259 259 ALA ALA A . n 
A 1 261 GLU 261 260 260 GLU GLU A . n 
A 1 262 GLY 262 261 261 GLY GLY A . n 
A 1 263 ARG 263 262 262 ARG ARG A . n 
A 1 264 ILE 264 263 263 ILE ILE A . n 
A 1 265 VAL 265 264 264 VAL VAL A . n 
A 1 266 PRO 266 265 265 PRO PRO A . n 
A 1 267 VAL 267 266 266 VAL VAL A . n 
A 1 268 GLY 268 267 267 GLY GLY A . n 
A 1 269 ALA 269 268 268 ALA ALA A . n 
A 1 270 GLY 270 269 269 GLY GLY A . n 
A 1 271 PRO 271 270 270 PRO PRO A . n 
A 1 272 ASP 272 271 271 ASP ASP A . n 
A 1 273 ARG 273 272 272 ARG ARG A . n 
A 1 274 TYR 274 273 273 TYR TYR A . n 
A 1 275 GLN 275 274 274 GLN GLN A . n 
A 1 276 PRO 276 275 275 PRO PRO A . n 
A 1 277 GLN 277 276 276 GLN GLN A . n 
A 1 278 GLN 278 277 277 GLN GLN A . n 
A 1 279 SER 279 278 278 SER SER A . n 
A 1 280 ILE 280 279 279 ILE ILE A . n 
A 1 281 ARG 281 280 280 ARG ARG A . n 
A 1 282 THR 282 281 281 THR THR A . n 
A 1 283 VAL 283 282 282 VAL VAL A . n 
A 1 284 PHE 284 283 283 PHE PHE A . n 
A 1 285 ASN 285 284 284 ASN ASN A . n 
A 1 286 VAL 286 285 285 VAL VAL A . n 
A 1 287 SER 287 286 286 SER SER A . n 
A 1 288 VAL 288 287 287 VAL VAL A . n 
A 1 289 PRO 289 288 288 PRO PRO A . n 
A 1 290 THR 290 289 289 THR THR A . n 
A 1 291 ARG 291 290 290 ARG ARG A . n 
A 1 292 HIS 292 291 291 HIS HIS A . n 
A 1 293 TYR 293 292 292 TYR TYR A . n 
A 1 294 VAL 294 293 293 VAL VAL A . n 
A 1 295 LYS 295 294 294 LYS LYS A . n 
A 1 296 THR 296 295 295 THR THR A . n 
A 1 297 ALA 297 296 296 ALA ALA A . n 
A 1 298 LEU 298 297 297 LEU LEU A . n 
A 1 299 SER 299 298 298 SER SER A . n 
A 1 300 ILE 300 299 299 ILE ILE A . n 
A 1 301 VAL 301 300 300 VAL VAL A . n 
A 1 302 ASN 302 301 301 ASN ASN A . n 
A 1 303 MET 303 302 302 MET MET A . n 
A 1 304 GLY 304 303 303 GLY GLY A . n 
A 1 305 PHE 305 304 304 PHE PHE A . n 
A 1 306 THR 306 305 305 THR THR A . n 
A 1 307 ARG 307 306 306 ARG ARG A . n 
A 1 308 GLY 308 307 307 GLY GLY A . n 
A 1 309 MET 309 308 308 MET MET A . n 
A 1 310 SER 310 309 309 SER SER A . n 
A 1 311 ALA 311 310 310 ALA ALA A . n 
A 1 312 ASP 312 311 311 ASP ASP A . n 
A 1 313 TYR 313 312 312 TYR TYR A . n 
A 1 314 MET 314 313 313 MET MET A . n 
A 1 315 ARG 315 314 314 ARG ARG A . n 
A 1 316 THR 316 315 315 THR THR A . n 
A 1 317 THR 317 316 316 THR THR A . n 
A 1 318 PRO 318 317 317 PRO PRO A . n 
A 1 319 LEU 319 318 318 LEU LEU A . n 
A 1 320 ILE 320 319 319 ILE ILE A . n 
A 1 321 ASN 321 320 320 ASN ASN A . n 
A 1 322 ASP 322 321 321 ASP ASP A . n 
A 1 323 TRP 323 322 322 TRP TRP A . n 
A 1 324 VAL 324 323 323 VAL VAL A . n 
A 1 325 ARG 325 324 324 ARG ARG A . n 
A 1 326 SER 326 325 325 SER SER A . n 
A 1 327 ARG 327 326 326 ARG ARG A . n 
A 1 328 VAL 328 327 327 VAL VAL A . n 
A 1 329 HIS 329 328 328 HIS HIS A . n 
A 1 330 GLY 330 329 329 GLY GLY A . n 
A 1 331 ASP 331 330 330 ASP ASP A . n 
A 1 332 PRO 332 331 331 PRO PRO A . n 
A 1 333 TYR 333 332 332 TYR TYR A . n 
A 1 334 LEU 334 333 333 LEU LEU A . n 
A 1 335 ALA 335 334 334 ALA ALA A . n 
A 1 336 SER 336 335 335 SER SER A . n 
A 1 337 ILE 337 336 336 ILE ILE A . n 
A 1 338 GLY 338 337 337 GLY GLY A . n 
A 1 339 PHE 339 338 338 PHE PHE A . n 
A 1 340 GLU 340 339 339 GLU GLU A . n 
A 1 341 MET 341 340 340 MET MET A . n 
A 1 342 ILE 342 341 341 ILE ILE A . n 
A 1 343 TYR 343 342 342 TYR TYR A . n 
A 1 344 GLU 344 343 343 GLU GLU A . n 
A 1 345 VAL 345 344 344 VAL VAL A . n 
A 1 346 ALA 346 345 345 ALA ALA A . n 
A 1 347 ALA 347 346 346 ALA ALA A . n 
A 1 348 ILE 348 347 347 ILE ILE A . n 
A 1 349 GLY 349 348 348 GLY GLY A . n 
A 1 350 TYR 350 349 349 TYR TYR A . n 
A 1 351 ARG 351 350 350 ARG ARG A . n 
A 1 352 ASN 352 351 351 ASN ASN A . n 
A 1 353 THR 353 352 352 THR THR A . n 
A 1 354 THR 354 353 353 THR THR A . n 
A 1 355 LEU 355 354 354 LEU LEU A . n 
A 1 356 THR 356 355 355 THR THR A . n 
A 1 357 ALA 357 356 356 ALA ALA A . n 
A 1 358 ILE 358 357 357 ILE ILE A . n 
A 1 359 THR 359 358 358 THR THR A . n 
A 1 360 ARG 360 359 359 ARG ARG A . n 
A 1 361 PRO 361 360 360 PRO PRO A . n 
A 1 362 GLY 362 361 361 GLY GLY A . n 
A 1 363 SER 363 362 362 SER SER A . n 
A 1 364 GLU 364 363 363 GLU GLU A . n 
A 1 365 TYR 365 364 364 TYR TYR A . n 
A 1 366 ARG 366 365 365 ARG ARG A . n 
A 1 367 LYS 367 366 366 LYS LYS A . n 
A 1 368 LEU 368 367 367 LEU LEU A . n 
A 1 369 LEU 369 368 368 LEU LEU A . n 
A 1 370 SER 370 369 369 SER SER A . n 
A 1 371 ALA 371 370 370 ALA ALA A . n 
A 1 372 LEU 372 371 371 LEU LEU A . n 
A 1 373 TRP 373 372 372 TRP TRP A . n 
A 1 374 ARG 374 373 373 ARG ARG A . n 
A 1 375 GLU 375 374 374 GLU GLU A . n 
A 1 376 SER 376 375 375 SER SER A . n 
A 1 377 PRO 377 376 376 PRO PRO A . n 
A 1 378 VAL 378 377 377 VAL VAL A . n 
A 1 379 SER 379 378 378 SER SER A . n 
A 1 380 ARG 380 379 379 ARG ARG A . n 
A 1 381 VAL 381 380 380 VAL VAL A . n 
A 1 382 ALA 382 381 381 ALA ALA A . n 
A 1 383 GLU 383 382 382 GLU GLU A . n 
A 1 384 HIS 384 383 383 HIS HIS A . n 
A 1 385 GLU 385 384 384 GLU GLU A . n 
A 1 386 GLN 386 385 385 GLN GLN A . n 
A 1 387 LEU 387 386 386 LEU LEU A . n 
A 1 388 THR 388 387 387 THR THR A . n 
A 1 389 THR 389 388 388 THR THR A . n 
A 1 390 MET 390 389 389 MET MET A . n 
A 1 391 ALA 391 390 390 ALA ALA A . n 
A 1 392 ALA 392 391 391 ALA ALA A . n 
A 1 393 LEU 393 392 392 LEU LEU A . n 
A 1 394 LEU 394 393 393 LEU LEU A . n 
A 1 395 HIS 395 394 394 HIS HIS A . n 
A 1 396 ILE 396 395 395 ILE ILE A . n 
A 1 397 ASP 397 396 396 ASP ASP A . n 
A 1 398 HIS 398 397 397 HIS HIS A . n 
A 1 399 ASN 399 398 398 ASN ASN A . n 
A 1 400 GLY 400 399 399 GLY GLY A . n 
A 1 401 ILE 401 400 400 ILE ILE A . n 
A 1 402 PRO 402 401 401 PRO PRO A . n 
A 1 403 LEU 403 402 402 LEU LEU A . n 
A 1 404 ALA 404 403 403 ALA ALA A . n 
A 1 405 GLY 405 404 404 GLY GLY A . n 
A 1 406 GLU 406 405 405 GLU GLU A . n 
A 1 407 PHE 407 406 406 PHE PHE A . n 
A 1 408 ILE 408 407 407 ILE ILE A . n 
A 1 409 GLN 409 408 408 GLN GLN A . n 
A 1 410 LYS 410 409 409 LYS LYS A . n 
A 1 411 SER 411 410 410 SER SER A . n 
A 1 412 GLY 412 411 411 GLY GLY A . n 
A 1 413 LEU 413 412 412 LEU LEU A . n 
A 1 414 ALA 414 413 413 ALA ALA A . n 
A 1 415 ALA 415 414 414 ALA ALA A . n 
A 1 416 GLN 416 415 415 GLN GLN A . n 
A 1 417 GLU 417 416 416 GLU GLU A . n 
A 1 418 TRP 418 417 417 TRP TRP A . n 
A 1 419 LEU 419 418 418 LEU LEU A . n 
A 1 420 ALA 420 419 419 ALA ALA A . n 
A 1 421 ARG 421 420 420 ARG ARG A . n 
A 1 422 TYR 422 421 421 TYR TYR A . n 
A 1 423 LEU 423 422 422 LEU LEU A . n 
A 1 424 ARG 424 423 423 ARG ARG A . n 
A 1 425 ALA 425 424 424 ALA ALA A . n 
A 1 426 TYR 426 425 425 TYR TYR A . n 
A 1 427 LEU 427 426 426 LEU LEU A . n 
A 1 428 HIS 428 427 427 HIS HIS A . n 
A 1 429 PRO 429 428 428 PRO PRO A . n 
A 1 430 ILE 430 429 429 ILE ILE A . n 
A 1 431 ILE 431 430 430 ILE ILE A . n 
A 1 432 TYR 432 431 431 TYR TYR A . n 
A 1 433 LEU 433 432 432 LEU LEU A . n 
A 1 434 LEU 434 433 433 LEU LEU A . n 
A 1 435 TYR 435 434 434 TYR TYR A . n 
A 1 436 ARG 436 435 435 ARG ARG A . n 
A 1 437 TYR 437 436 436 TYR TYR A . n 
A 1 438 GLU 438 437 437 GLU GLU A . n 
A 1 439 PHE 439 438 438 PHE PHE A . n 
A 1 440 LYS 440 439 439 LYS LYS A . n 
A 1 441 PHE 441 440 440 PHE PHE A . n 
A 1 442 SER 442 441 441 SER SER A . n 
A 1 443 PRO 443 442 442 PRO PRO A . n 
A 1 444 HIS 444 443 443 HIS HIS A . n 
A 1 445 GLY 445 444 444 GLY GLY A . n 
A 1 446 GLU 446 445 445 GLU GLU A . n 
A 1 447 ASN 447 446 446 ASN ASN A . n 
A 1 448 LEU 448 447 447 LEU LEU A . n 
A 1 449 ILE 449 448 448 ILE ILE A . n 
A 1 450 LEU 450 449 449 LEU LEU A . n 
A 1 451 VAL 451 450 450 VAL VAL A . n 
A 1 452 LEU 452 451 451 LEU LEU A . n 
A 1 453 ASP 453 452 452 ASP ASP A . n 
A 1 454 GLY 454 453 453 GLY GLY A . n 
A 1 455 GLY 455 454 454 GLY GLY A . n 
A 1 456 ALA 456 455 455 ALA ALA A . n 
A 1 457 PRO 457 456 456 PRO PRO A . n 
A 1 458 VAL 458 457 457 VAL VAL A . n 
A 1 459 ARG 459 458 458 ARG ARG A . n 
A 1 460 ALA 460 459 459 ALA ALA A . n 
A 1 461 VAL 461 460 460 VAL VAL A . n 
A 1 462 LEU 462 461 461 LEU LEU A . n 
A 1 463 LYS 463 462 462 LYS LYS A . n 
A 1 464 ASP 464 463 463 ASP ASP A . n 
A 1 465 ILE 465 464 464 ILE ILE A . n 
A 1 466 GLY 466 465 465 GLY GLY A . n 
A 1 467 GLU 467 466 466 GLU GLU A . n 
A 1 468 GLU 468 467 467 GLU GLU A . n 
A 1 469 ILE 469 468 468 ILE ILE A . n 
A 1 470 CYS 470 469 469 CYS CYS A . n 
A 1 471 ILE 471 470 470 ILE ILE A . n 
A 1 472 PHE 472 471 471 PHE PHE A . n 
A 1 473 ASP 473 472 472 ASP ASP A . n 
A 1 474 ALA 474 473 473 ALA ALA A . n 
A 1 475 PRO 475 474 474 PRO PRO A . n 
A 1 476 ASP 476 475 475 ASP ASP A . n 
A 1 477 ASP 477 476 476 ASP ASP A . n 
A 1 478 ILE 478 477 477 ILE ILE A . n 
A 1 479 PRO 479 478 478 PRO PRO A . n 
A 1 480 GLU 480 479 479 GLU GLU A . n 
A 1 481 SER 481 480 480 SER SER A . n 
A 1 482 CYS 482 481 481 CYS CYS A . n 
A 1 483 ARG 483 482 482 ARG ARG A . n 
A 1 484 ARG 484 483 483 ARG ARG A . n 
A 1 485 ALA 485 484 484 ALA ALA A . n 
A 1 486 VAL 486 485 485 VAL VAL A . n 
A 1 487 THR 487 486 486 THR THR A . n 
A 1 488 GLU 488 487 487 GLU GLU A . n 
A 1 489 GLU 489 488 488 GLU GLU A . n 
A 1 490 ALA 490 489 489 ALA ALA A . n 
A 1 491 ASP 491 490 490 ASP ASP A . n 
A 1 492 GLU 492 491 491 GLU GLU A . n 
A 1 493 ILE 493 492 492 ILE ILE A . n 
A 1 494 ARG 494 493 493 ARG ARG A . n 
A 1 495 ASN 495 494 494 ASN ASN A . n 
A 1 496 LEU 496 495 495 LEU LEU A . n 
A 1 497 GLY 497 496 496 GLY GLY A . n 
A 1 498 VAL 498 497 497 VAL VAL A . n 
A 1 499 LEU 499 498 498 LEU LEU A . n 
A 1 500 SER 500 499 499 SER SER A . n 
A 1 501 ASP 501 500 500 ASP ASP A . n 
A 1 502 VAL 502 501 501 VAL VAL A . n 
A 1 503 PHE 503 502 502 PHE PHE A . n 
A 1 504 ASP 504 503 503 ASP ASP A . n 
A 1 505 ASP 505 504 504 ASP ASP A . n 
A 1 506 PHE 506 505 505 PHE PHE A . n 
A 1 507 LEU 507 506 506 LEU LEU A . n 
A 1 508 ARG 508 507 507 ARG ARG A . n 
A 1 509 HIS 509 508 508 HIS HIS A . n 
A 1 510 PHE 510 509 509 PHE PHE A . n 
A 1 511 ALA 511 510 510 ALA ALA A . n 
A 1 512 LEU 512 511 511 LEU LEU A . n 
A 1 513 LEU 513 512 512 LEU LEU A . n 
A 1 514 LEU 514 513 513 LEU LEU A . n 
A 1 515 HIS 515 514 514 HIS HIS A . n 
A 1 516 GLU 516 515 515 GLU GLU A . n 
A 1 517 SER 517 516 516 SER SER A . n 
A 1 518 GLY 518 517 517 GLY GLY A . n 
A 1 519 LEU 519 518 518 LEU LEU A . n 
A 1 520 LEU 520 519 519 LEU LEU A . n 
A 1 521 THR 521 520 520 THR THR A . n 
A 1 522 ASP 522 521 521 ASP ASP A . n 
A 1 523 GLY 523 522 522 GLY GLY A . n 
A 1 524 GLU 524 523 523 GLU GLU A . n 
A 1 525 PHE 525 524 524 PHE PHE A . n 
A 1 526 TRP 526 525 525 TRP TRP A . n 
A 1 527 ALA 527 526 526 ALA ALA A . n 
A 1 528 THR 528 527 527 THR THR A . n 
A 1 529 VAL 529 528 528 VAL VAL A . n 
A 1 530 ALA 530 529 529 ALA ALA A . n 
A 1 531 HIS 531 530 530 HIS HIS A . n 
A 1 532 SER 532 531 531 SER SER A . n 
A 1 533 VAL 533 532 532 VAL VAL A . n 
A 1 534 ALA 534 533 533 ALA ALA A . n 
A 1 535 GLU 535 534 534 GLU GLU A . n 
A 1 536 PHE 536 535 535 PHE PHE A . n 
A 1 537 GLN 537 536 536 GLN GLN A . n 
A 1 538 ALA 538 537 537 ALA ALA A . n 
A 1 539 ARG 539 538 538 ARG ARG A . n 
A 1 540 HIS 540 539 539 HIS HIS A . n 
A 1 541 PRO 541 540 540 PRO PRO A . n 
A 1 542 ASP 542 541 541 ASP ASP A . n 
A 1 543 LEU 543 542 542 LEU LEU A . n 
A 1 544 ALA 544 543 543 ALA ALA A . n 
A 1 545 ASP 545 544 544 ASP ASP A . n 
A 1 546 ARG 546 545 545 ARG ARG A . n 
A 1 547 PHE 547 546 546 PHE PHE A . n 
A 1 548 ASP 548 547 547 ASP ASP A . n 
A 1 549 GLN 549 548 548 GLN GLN A . n 
A 1 550 TRP 550 549 549 TRP TRP A . n 
A 1 551 ASP 551 550 550 ASP ASP A . n 
A 1 552 LEU 552 551 551 LEU LEU A . n 
A 1 553 PHE 553 552 552 PHE PHE A . n 
A 1 554 ALA 554 553 553 ALA ALA A . n 
A 1 555 PRO 555 554 554 PRO PRO A . n 
A 1 556 THR 556 555 555 THR THR A . n 
A 1 557 PHE 557 556 556 PHE PHE A . n 
A 1 558 PRO 558 557 557 PRO PRO A . n 
A 1 559 ALA 559 558 558 ALA ALA A . n 
A 1 560 ILE 560 559 559 ILE ILE A . n 
A 1 561 HIS 561 560 560 HIS HIS A . n 
A 1 562 MET 562 561 561 MET MET A . n 
A 1 563 ASN 563 562 562 ASN ASN A . n 
A 1 564 ARG 564 563 563 ARG ARG A . n 
A 1 565 LEU 565 564 564 LEU LEU A . n 
A 1 566 GLN 566 565 565 GLN GLN A . n 
A 1 567 LEU 567 566 566 LEU LEU A . n 
A 1 568 SER 568 567 567 SER SER A . n 
A 1 569 ASN 569 568 ?   ?   ?   A . n 
A 1 570 ASN 570 569 ?   ?   ?   A . n 
A 1 571 ARG 571 570 ?   ?   ?   A . n 
A 1 572 ARG 572 571 ?   ?   ?   A . n 
A 1 573 MET 573 572 572 MET MET A . n 
A 1 574 VAL 574 573 573 VAL VAL A . n 
A 1 575 ASN 575 574 ?   ?   ?   A . n 
A 1 576 LEU 576 575 ?   ?   ?   A . n 
A 1 577 GLY 577 576 ?   ?   ?   A . n 
A 1 578 ASP 578 577 ?   ?   ?   A . n 
A 1 579 SER 579 578 578 SER SER A . n 
A 1 580 TYR 580 579 579 TYR TYR A . n 
A 1 581 SER 581 580 580 SER SER A . n 
A 1 582 THR 582 581 581 THR THR A . n 
A 1 583 LEU 583 582 582 LEU LEU A . n 
A 1 584 VAL 584 583 583 VAL VAL A . n 
A 1 585 ASP 585 584 584 ASP ASP A . n 
A 1 586 ASN 586 585 585 ASN ASN A . n 
A 1 587 GLU 587 586 586 GLU GLU A . n 
A 1 588 HIS 588 587 587 HIS HIS A . n 
A 1 589 ALA 589 588 588 ALA ALA A . n 
A 1 590 LEU 590 589 589 LEU LEU A . n 
A 1 591 VAL 591 590 590 VAL VAL A . n 
A 1 592 ASN 592 591 591 ASN ASN A . n 
A 1 593 PRO 593 592 592 PRO PRO A . n 
A 1 594 ILE 594 593 593 ILE ILE A . n 
A 1 595 ALA 595 594 594 ALA ALA A . n 
A 1 596 GLY 596 595 595 GLY GLY A . n 
A 1 597 HIS 597 596 596 HIS HIS A . n 
A 1 598 ARG 598 597 597 ARG ARG A . n 
A 1 599 GLY 599 598 ?   ?   ?   A . n 
A 1 600 ALA 600 599 ?   ?   ?   A . n 
A 1 601 VAL 601 600 ?   ?   ?   A . n 
A 1 602 THR 602 601 ?   ?   ?   A . n 
A 1 603 THR 603 602 ?   ?   ?   A . n 
A 1 604 THR 604 603 ?   ?   ?   A . n 
A 1 605 SER 605 604 ?   ?   ?   A . n 
A 1 606 GLY 606 605 ?   ?   ?   A . n 
A 1 607 ALA 607 606 ?   ?   ?   A . n 
A 1 608 GLU 608 607 ?   ?   ?   A . n 
A 1 609 VAL 609 608 ?   ?   ?   A . n 
A 1 610 HIS 610 609 ?   ?   ?   A . n 
A 1 611 ALA 611 610 ?   ?   ?   A . n 
A 1 612 ALA 612 611 ?   ?   ?   A . n 
B 1 1   GLY 1   0   ?   ?   ?   B . n 
B 1 2   HIS 2   1   ?   ?   ?   B . n 
B 1 3   MET 3   2   ?   ?   ?   B . n 
B 1 4   SER 4   3   ?   ?   ?   B . n 
B 1 5   ILE 5   4   ?   ?   ?   B . n 
B 1 6   ASP 6   5   ?   ?   ?   B . n 
B 1 7   ILE 7   6   ?   ?   ?   B . n 
B 1 8   ARG 8   7   ?   ?   ?   B . n 
B 1 9   GLY 9   8   ?   ?   ?   B . n 
B 1 10  ALA 10  9   ?   ?   ?   B . n 
B 1 11  THR 11  10  ?   ?   ?   B . n 
B 1 12  GLU 12  11  ?   ?   ?   B . n 
B 1 13  VAL 13  12  ?   ?   ?   B . n 
B 1 14  PRO 14  13  ?   ?   ?   B . n 
B 1 15  ALA 15  14  ?   ?   ?   B . n 
B 1 16  PRO 16  15  ?   ?   ?   B . n 
B 1 17  ALA 17  16  16  ALA ALA B . n 
B 1 18  CYS 18  17  17  CYS CYS B . n 
B 1 19  SER 19  18  18  SER SER B . n 
B 1 20  TYR 20  19  19  TYR TYR B . n 
B 1 21  ARG 21  20  20  ARG ARG B . n 
B 1 22  GLN 22  21  21  GLN GLN B . n 
B 1 23  VAL 23  22  22  VAL VAL B . n 
B 1 24  TYR 24  23  23  TYR TYR B . n 
B 1 25  ASN 25  24  24  ASN ASN B . n 
B 1 26  THR 26  25  25  THR THR B . n 
B 1 27  ARG 27  26  26  ARG ARG B . n 
B 1 28  LEU 28  27  27  LEU LEU B . n 
B 1 29  ALA 29  28  28  ALA ALA B . n 
B 1 30  ARG 30  29  29  ARG ARG B . n 
B 1 31  LYS 31  30  30  LYS LYS B . n 
B 1 32  ILE 32  31  31  ILE ILE B . n 
B 1 33  LEU 33  32  32  LEU LEU B . n 
B 1 34  ALA 34  33  33  ALA ALA B . n 
B 1 35  GLU 35  34  34  GLU GLU B . n 
B 1 36  PHE 36  35  35  PHE PHE B . n 
B 1 37  CYS 37  36  36  CYS CYS B . n 
B 1 38  HIS 38  37  37  HIS HIS B . n 
B 1 39  GLU 39  38  38  GLU GLU B . n 
B 1 40  ARG 40  39  39  ARG ARG B . n 
B 1 41  LEU 41  40  40  LEU LEU B . n 
B 1 42  VAL 42  41  41  VAL VAL B . n 
B 1 43  ARG 43  42  42  ARG ARG B . n 
B 1 44  PRO 44  43  43  PRO PRO B . n 
B 1 45  THR 45  44  44  THR THR B . n 
B 1 46  GLU 46  45  45  GLU GLU B . n 
B 1 47  LEU 47  46  46  LEU LEU B . n 
B 1 48  SER 48  47  47  SER SER B . n 
B 1 49  PRO 49  48  48  PRO PRO B . n 
B 1 50  GLY 50  49  49  GLY GLY B . n 
B 1 51  ARG 51  50  50  ARG ARG B . n 
B 1 52  TYR 52  51  51  TYR TYR B . n 
B 1 53  VAL 53  52  52  VAL VAL B . n 
B 1 54  VAL 54  53  53  VAL VAL B . n 
B 1 55  HIS 55  54  54  HIS HIS B . n 
B 1 56  SER 56  55  55  SER SER B . n 
B 1 57  ASP 57  56  56  ASP ASP B . n 
B 1 58  ASP 58  57  57  ASP ASP B . n 
B 1 59  ARG 59  58  58  ARG ARG B . n 
B 1 60  GLU 60  59  59  GLU GLU B . n 
B 1 61  THR 61  60  60  THR THR B . n 
B 1 62  GLU 62  61  61  GLU GLU B . n 
B 1 63  TYR 63  62  62  TYR TYR B . n 
B 1 64  ARG 64  63  63  ARG ARG B . n 
B 1 65  PHE 65  64  64  PHE PHE B . n 
B 1 66  ARG 66  65  65  ARG ARG B . n 
B 1 67  ALA 67  66  66  ALA ALA B . n 
B 1 68  GLU 68  67  67  GLU GLU B . n 
B 1 69  ILE 69  68  68  ILE ILE B . n 
B 1 70  LEU 70  69  69  LEU LEU B . n 
B 1 71  SER 71  70  70  SER SER B . n 
B 1 72  LEU 72  71  71  LEU LEU B . n 
B 1 73  ASP 73  72  72  ASP ASP B . n 
B 1 74  SER 74  73  73  SER SER B . n 
B 1 75  TRP 75  74  74  TRP TRP B . n 
B 1 76  CYS 76  75  75  CYS CYS B . n 
B 1 77  ILE 77  76  76  ILE ILE B . n 
B 1 78  ASP 78  77  77  ASP ASP B . n 
B 1 79  ALA 79  78  78  ALA ALA B . n 
B 1 80  ALA 80  79  79  ALA ALA B . n 
B 1 81  SER 81  80  80  SER SER B . n 
B 1 82  LEU 82  81  81  LEU LEU B . n 
B 1 83  ARG 83  82  82  ARG ARG B . n 
B 1 84  ARG 84  83  83  ARG ARG B . n 
B 1 85  VAL 85  84  84  VAL VAL B . n 
B 1 86  ARG 86  85  85  ARG ARG B . n 
B 1 87  LYS 87  86  86  LYS LYS B . n 
B 1 88  GLY 88  87  87  GLY GLY B . n 
B 1 89  GLU 89  88  88  GLU GLU B . n 
B 1 90  GLU 90  89  89  GLU GLU B . n 
B 1 91  LEU 91  90  90  LEU LEU B . n 
B 1 92  ARG 92  91  91  ARG ARG B . n 
B 1 93  ILE 93  92  92  ILE ILE B . n 
B 1 94  ASP 94  93  93  ASP ASP B . n 
B 1 95  ALA 95  94  94  ALA ALA B . n 
B 1 96  ILE 96  95  95  ILE ILE B . n 
B 1 97  ASP 97  96  96  ASP ASP B . n 
B 1 98  LEU 98  97  97  LEU LEU B . n 
B 1 99  ILE 99  98  98  ILE ILE B . n 
B 1 100 VAL 100 99  99  VAL VAL B . n 
B 1 101 ASP 101 100 100 ASP ASP B . n 
B 1 102 MET 102 101 101 MET MET B . n 
B 1 103 SER 103 102 102 SER SER B . n 
B 1 104 GLY 104 103 103 GLY GLY B . n 
B 1 105 SER 105 104 104 SER SER B . n 
B 1 106 LEU 106 105 105 LEU LEU B . n 
B 1 107 GLY 107 106 106 GLY GLY B . n 
B 1 108 ILE 108 107 107 ILE ILE B . n 
B 1 109 PRO 109 108 108 PRO PRO B . n 
B 1 110 VAL 110 109 109 VAL VAL B . n 
B 1 111 ASP 111 110 110 ASP ASP B . n 
B 1 112 ALA 112 111 111 ALA ALA B . n 
B 1 113 LEU 113 112 112 LEU LEU B . n 
B 1 114 PRO 114 113 113 PRO PRO B . n 
B 1 115 GLU 115 114 114 GLU GLU B . n 
B 1 116 TYR 116 115 115 TYR TYR B . n 
B 1 117 LEU 117 116 116 LEU LEU B . n 
B 1 118 GLU 118 117 117 GLU GLU B . n 
B 1 119 GLU 119 118 118 GLU GLU B . n 
B 1 120 PHE 120 119 119 PHE PHE B . n 
B 1 121 THR 121 120 120 THR THR B . n 
B 1 122 ASN 122 121 121 ASN ASN B . n 
B 1 123 THR 123 122 122 THR THR B . n 
B 1 124 ALA 124 123 123 ALA ALA B . n 
B 1 125 SER 125 124 124 SER SER B . n 
B 1 126 ILE 126 125 125 ILE ILE B . n 
B 1 127 SER 127 126 126 SER SER B . n 
B 1 128 MET 128 127 127 MET MET B . n 
B 1 129 ASP 129 128 128 ASP ASP B . n 
B 1 130 ARG 130 129 129 ARG ARG B . n 
B 1 131 PRO 131 130 130 PRO PRO B . n 
B 1 132 ASP 132 131 131 ASP ASP B . n 
B 1 133 THR 133 132 132 THR THR B . n 
B 1 134 ARG 134 133 133 ARG ARG B . n 
B 1 135 ARG 135 134 134 ARG ARG B . n 
B 1 136 ILE 136 135 135 ILE ILE B . n 
B 1 137 PRO 137 136 136 PRO PRO B . n 
B 1 138 ALA 138 137 137 ALA ALA B . n 
B 1 139 ALA 139 138 138 ALA ALA B . n 
B 1 140 GLU 140 139 139 GLU GLU B . n 
B 1 141 LEU 141 140 140 LEU LEU B . n 
B 1 142 ALA 142 141 141 ALA ALA B . n 
B 1 143 VAL 143 142 142 VAL VAL B . n 
B 1 144 ALA 144 143 143 ALA ALA B . n 
B 1 145 ASP 145 144 144 ASP ASP B . n 
B 1 146 PHE 146 145 145 PHE PHE B . n 
B 1 147 GLN 147 146 146 GLN GLN B . n 
B 1 148 THR 148 147 147 THR THR B . n 
B 1 149 ILE 149 148 148 ILE ILE B . n 
B 1 150 GLU 150 149 149 GLU GLU B . n 
B 1 151 LYS 151 150 150 LYS LYS B . n 
B 1 152 THR 152 151 151 THR THR B . n 
B 1 153 MET 153 152 152 MET MET B . n 
B 1 154 THR 154 153 153 THR THR B . n 
B 1 155 GLU 155 154 154 GLU GLU B . n 
B 1 156 GLY 156 155 155 GLY GLY B . n 
B 1 157 HIS 157 156 156 HIS HIS B . n 
B 1 158 PRO 158 157 157 PRO PRO B . n 
B 1 159 CYS 159 158 158 CYS CYS B . n 
B 1 160 LEU 160 159 159 LEU LEU B . n 
B 1 161 VAL 161 160 160 VAL VAL B . n 
B 1 162 ALA 162 161 161 ALA ALA B . n 
B 1 163 ASN 163 162 162 ASN ASN B . n 
B 1 164 ALA 164 163 163 ALA ALA B . n 
B 1 165 GLY 165 164 164 GLY GLY B . n 
B 1 166 ARG 166 165 165 ARG ARG B . n 
B 1 167 LEU 167 166 166 LEU LEU B . n 
B 1 168 GLY 168 167 167 GLY GLY B . n 
B 1 169 PHE 169 168 168 PHE PHE B . n 
B 1 170 SER 170 169 169 SER SER B . n 
B 1 171 ALA 171 170 170 ALA ALA B . n 
B 1 172 ASP 172 171 171 ASP ASP B . n 
B 1 173 ASP 173 172 172 ASP ASP B . n 
B 1 174 ILE 174 173 173 ILE ILE B . n 
B 1 175 GLU 175 174 174 GLU GLU B . n 
B 1 176 ARG 176 175 175 ARG ARG B . n 
B 1 177 TYR 177 176 176 TYR TYR B . n 
B 1 178 ALA 178 177 177 ALA ALA B . n 
B 1 179 PRO 179 178 178 PRO PRO B . n 
B 1 180 GLU 180 179 179 GLU GLU B . n 
B 1 181 SER 181 180 180 SER SER B . n 
B 1 182 GLY 182 181 181 GLY GLY B . n 
B 1 183 GLY 183 182 182 GLY GLY B . n 
B 1 184 ARG 184 183 183 ARG ARG B . n 
B 1 185 PHE 185 184 184 PHE PHE B . n 
B 1 186 ALA 186 185 185 ALA ALA B . n 
B 1 187 LEU 187 186 186 LEU LEU B . n 
B 1 188 GLU 188 187 187 GLU GLU B . n 
B 1 189 TRP 189 188 188 TRP TRP B . n 
B 1 190 VAL 190 189 189 VAL VAL B . n 
B 1 191 ALA 191 190 190 ALA ALA B . n 
B 1 192 VAL 192 191 191 VAL VAL B . n 
B 1 193 LEU 193 192 192 LEU LEU B . n 
B 1 194 ARG 194 193 193 ARG ARG B . n 
B 1 195 VAL 195 194 194 VAL VAL B . n 
B 1 196 ASN 196 195 195 ASN ASN B . n 
B 1 197 THR 197 196 196 THR THR B . n 
B 1 198 ASP 198 197 197 ASP ASP B . n 
B 1 199 PHE 199 198 198 PHE PHE B . n 
B 1 200 ALA 200 199 199 ALA ALA B . n 
B 1 201 ALA 201 200 200 ALA ALA B . n 
B 1 202 MET 202 201 201 MET MET B . n 
B 1 203 SER 203 202 202 SER SER B . n 
B 1 204 GLY 204 203 203 GLY GLY B . n 
B 1 205 THR 205 204 204 THR THR B . n 
B 1 206 GLU 206 205 205 GLU GLU B . n 
B 1 207 TYR 207 206 206 TYR TYR B . n 
B 1 208 ASP 208 207 207 ASP ASP B . n 
B 1 209 THR 209 208 208 THR THR B . n 
B 1 210 LEU 210 209 209 LEU LEU B . n 
B 1 211 ILE 211 210 210 ILE ILE B . n 
B 1 212 ARG 212 211 211 ARG ARG B . n 
B 1 213 ASP 213 212 212 ASP ASP B . n 
B 1 214 GLU 214 213 213 GLU GLU B . n 
B 1 215 LEU 215 214 214 LEU LEU B . n 
B 1 216 GLY 216 215 215 GLY GLY B . n 
B 1 217 ALA 217 216 216 ALA ALA B . n 
B 1 218 ASP 218 217 217 ASP ASP B . n 
B 1 219 THR 219 218 218 THR THR B . n 
B 1 220 LEU 220 219 219 LEU LEU B . n 
B 1 221 ALA 221 220 220 ALA ALA B . n 
B 1 222 ARG 222 221 221 ARG ARG B . n 
B 1 223 PHE 223 222 222 PHE PHE B . n 
B 1 224 ASP 224 223 223 ASP ASP B . n 
B 1 225 ARG 225 224 224 ARG ARG B . n 
B 1 226 VAL 226 225 225 VAL VAL B . n 
B 1 227 LEU 227 226 226 LEU LEU B . n 
B 1 228 THR 228 227 227 THR THR B . n 
B 1 229 GLY 229 228 228 GLY GLY B . n 
B 1 230 ARG 230 229 229 ARG ARG B . n 
B 1 231 GLY 231 230 230 GLY GLY B . n 
B 1 232 LEU 232 231 231 LEU LEU B . n 
B 1 233 ASP 233 232 232 ASP ASP B . n 
B 1 234 PRO 234 233 233 PRO PRO B . n 
B 1 235 ALA 235 234 234 ALA ALA B . n 
B 1 236 SER 236 235 235 SER SER B . n 
B 1 237 TYR 237 236 236 TYR TYR B . n 
B 1 238 TYR 238 237 237 TYR TYR B . n 
B 1 239 TYR 239 238 238 TYR TYR B . n 
B 1 240 MET 240 239 239 MET MET B . n 
B 1 241 PRO 241 240 240 PRO PRO B . n 
B 1 242 VAL 242 241 241 VAL VAL B . n 
B 1 243 HIS 243 242 242 HIS HIS B . n 
B 1 244 PRO 244 243 243 PRO PRO B . n 
B 1 245 TRP 245 244 244 TRP TRP B . n 
B 1 246 GLN 246 245 245 GLN GLN B . n 
B 1 247 TRP 247 246 246 TRP TRP B . n 
B 1 248 ALA 248 247 247 ALA ALA B . n 
B 1 249 GLU 249 248 248 GLU GLU B . n 
B 1 250 LYS 250 249 249 LYS LYS B . n 
B 1 251 ILE 251 250 250 ILE ILE B . n 
B 1 252 ALA 252 251 251 ALA ALA B . n 
B 1 253 ARG 253 252 252 ARG ARG B . n 
B 1 254 ILE 254 253 253 ILE ILE B . n 
B 1 255 TYR 255 254 254 TYR TYR B . n 
B 1 256 ALA 256 255 255 ALA ALA B . n 
B 1 257 VAL 257 256 256 VAL VAL B . n 
B 1 258 ASP 258 257 257 ASP ASP B . n 
B 1 259 ILE 259 258 258 ILE ILE B . n 
B 1 260 ALA 260 259 259 ALA ALA B . n 
B 1 261 GLU 261 260 260 GLU GLU B . n 
B 1 262 GLY 262 261 261 GLY GLY B . n 
B 1 263 ARG 263 262 262 ARG ARG B . n 
B 1 264 ILE 264 263 263 ILE ILE B . n 
B 1 265 VAL 265 264 264 VAL VAL B . n 
B 1 266 PRO 266 265 265 PRO PRO B . n 
B 1 267 VAL 267 266 266 VAL VAL B . n 
B 1 268 GLY 268 267 267 GLY GLY B . n 
B 1 269 ALA 269 268 268 ALA ALA B . n 
B 1 270 GLY 270 269 269 GLY GLY B . n 
B 1 271 PRO 271 270 270 PRO PRO B . n 
B 1 272 ASP 272 271 271 ASP ASP B . n 
B 1 273 ARG 273 272 272 ARG ARG B . n 
B 1 274 TYR 274 273 273 TYR TYR B . n 
B 1 275 GLN 275 274 274 GLN GLN B . n 
B 1 276 PRO 276 275 275 PRO PRO B . n 
B 1 277 GLN 277 276 276 GLN GLN B . n 
B 1 278 GLN 278 277 277 GLN GLN B . n 
B 1 279 SER 279 278 278 SER SER B . n 
B 1 280 ILE 280 279 279 ILE ILE B . n 
B 1 281 ARG 281 280 280 ARG ARG B . n 
B 1 282 THR 282 281 281 THR THR B . n 
B 1 283 VAL 283 282 282 VAL VAL B . n 
B 1 284 PHE 284 283 283 PHE PHE B . n 
B 1 285 ASN 285 284 284 ASN ASN B . n 
B 1 286 VAL 286 285 285 VAL VAL B . n 
B 1 287 SER 287 286 286 SER SER B . n 
B 1 288 VAL 288 287 287 VAL VAL B . n 
B 1 289 PRO 289 288 288 PRO PRO B . n 
B 1 290 THR 290 289 289 THR THR B . n 
B 1 291 ARG 291 290 290 ARG ARG B . n 
B 1 292 HIS 292 291 291 HIS HIS B . n 
B 1 293 TYR 293 292 292 TYR TYR B . n 
B 1 294 VAL 294 293 293 VAL VAL B . n 
B 1 295 LYS 295 294 294 LYS LYS B . n 
B 1 296 THR 296 295 295 THR THR B . n 
B 1 297 ALA 297 296 296 ALA ALA B . n 
B 1 298 LEU 298 297 297 LEU LEU B . n 
B 1 299 SER 299 298 298 SER SER B . n 
B 1 300 ILE 300 299 299 ILE ILE B . n 
B 1 301 VAL 301 300 300 VAL VAL B . n 
B 1 302 ASN 302 301 301 ASN ASN B . n 
B 1 303 MET 303 302 302 MET MET B . n 
B 1 304 GLY 304 303 303 GLY GLY B . n 
B 1 305 PHE 305 304 304 PHE PHE B . n 
B 1 306 THR 306 305 305 THR THR B . n 
B 1 307 ARG 307 306 306 ARG ARG B . n 
B 1 308 GLY 308 307 307 GLY GLY B . n 
B 1 309 MET 309 308 308 MET MET B . n 
B 1 310 SER 310 309 309 SER SER B . n 
B 1 311 ALA 311 310 310 ALA ALA B . n 
B 1 312 ASP 312 311 311 ASP ASP B . n 
B 1 313 TYR 313 312 312 TYR TYR B . n 
B 1 314 MET 314 313 313 MET MET B . n 
B 1 315 ARG 315 314 314 ARG ARG B . n 
B 1 316 THR 316 315 315 THR THR B . n 
B 1 317 THR 317 316 316 THR THR B . n 
B 1 318 PRO 318 317 317 PRO PRO B . n 
B 1 319 LEU 319 318 318 LEU LEU B . n 
B 1 320 ILE 320 319 319 ILE ILE B . n 
B 1 321 ASN 321 320 320 ASN ASN B . n 
B 1 322 ASP 322 321 321 ASP ASP B . n 
B 1 323 TRP 323 322 322 TRP TRP B . n 
B 1 324 VAL 324 323 323 VAL VAL B . n 
B 1 325 ARG 325 324 324 ARG ARG B . n 
B 1 326 SER 326 325 325 SER SER B . n 
B 1 327 ARG 327 326 326 ARG ARG B . n 
B 1 328 VAL 328 327 327 VAL VAL B . n 
B 1 329 HIS 329 328 328 HIS HIS B . n 
B 1 330 GLY 330 329 329 GLY GLY B . n 
B 1 331 ASP 331 330 330 ASP ASP B . n 
B 1 332 PRO 332 331 331 PRO PRO B . n 
B 1 333 TYR 333 332 332 TYR TYR B . n 
B 1 334 LEU 334 333 333 LEU LEU B . n 
B 1 335 ALA 335 334 334 ALA ALA B . n 
B 1 336 SER 336 335 335 SER SER B . n 
B 1 337 ILE 337 336 336 ILE ILE B . n 
B 1 338 GLY 338 337 337 GLY GLY B . n 
B 1 339 PHE 339 338 338 PHE PHE B . n 
B 1 340 GLU 340 339 339 GLU GLU B . n 
B 1 341 MET 341 340 340 MET MET B . n 
B 1 342 ILE 342 341 341 ILE ILE B . n 
B 1 343 TYR 343 342 342 TYR TYR B . n 
B 1 344 GLU 344 343 343 GLU GLU B . n 
B 1 345 VAL 345 344 344 VAL VAL B . n 
B 1 346 ALA 346 345 345 ALA ALA B . n 
B 1 347 ALA 347 346 346 ALA ALA B . n 
B 1 348 ILE 348 347 347 ILE ILE B . n 
B 1 349 GLY 349 348 348 GLY GLY B . n 
B 1 350 TYR 350 349 349 TYR TYR B . n 
B 1 351 ARG 351 350 350 ARG ARG B . n 
B 1 352 ASN 352 351 351 ASN ASN B . n 
B 1 353 THR 353 352 352 THR THR B . n 
B 1 354 THR 354 353 353 THR THR B . n 
B 1 355 LEU 355 354 354 LEU LEU B . n 
B 1 356 THR 356 355 355 THR THR B . n 
B 1 357 ALA 357 356 356 ALA ALA B . n 
B 1 358 ILE 358 357 357 ILE ILE B . n 
B 1 359 THR 359 358 358 THR THR B . n 
B 1 360 ARG 360 359 359 ARG ARG B . n 
B 1 361 PRO 361 360 360 PRO PRO B . n 
B 1 362 GLY 362 361 361 GLY GLY B . n 
B 1 363 SER 363 362 362 SER SER B . n 
B 1 364 GLU 364 363 363 GLU GLU B . n 
B 1 365 TYR 365 364 364 TYR TYR B . n 
B 1 366 ARG 366 365 365 ARG ARG B . n 
B 1 367 LYS 367 366 366 LYS LYS B . n 
B 1 368 LEU 368 367 367 LEU LEU B . n 
B 1 369 LEU 369 368 368 LEU LEU B . n 
B 1 370 SER 370 369 369 SER SER B . n 
B 1 371 ALA 371 370 370 ALA ALA B . n 
B 1 372 LEU 372 371 371 LEU LEU B . n 
B 1 373 TRP 373 372 372 TRP TRP B . n 
B 1 374 ARG 374 373 373 ARG ARG B . n 
B 1 375 GLU 375 374 374 GLU GLU B . n 
B 1 376 SER 376 375 375 SER SER B . n 
B 1 377 PRO 377 376 376 PRO PRO B . n 
B 1 378 VAL 378 377 377 VAL VAL B . n 
B 1 379 SER 379 378 378 SER SER B . n 
B 1 380 ARG 380 379 379 ARG ARG B . n 
B 1 381 VAL 381 380 380 VAL VAL B . n 
B 1 382 ALA 382 381 381 ALA ALA B . n 
B 1 383 GLU 383 382 382 GLU GLU B . n 
B 1 384 HIS 384 383 383 HIS HIS B . n 
B 1 385 GLU 385 384 384 GLU GLU B . n 
B 1 386 GLN 386 385 385 GLN GLN B . n 
B 1 387 LEU 387 386 386 LEU LEU B . n 
B 1 388 THR 388 387 387 THR THR B . n 
B 1 389 THR 389 388 388 THR THR B . n 
B 1 390 MET 390 389 389 MET MET B . n 
B 1 391 ALA 391 390 390 ALA ALA B . n 
B 1 392 ALA 392 391 391 ALA ALA B . n 
B 1 393 LEU 393 392 392 LEU LEU B . n 
B 1 394 LEU 394 393 393 LEU LEU B . n 
B 1 395 HIS 395 394 394 HIS HIS B . n 
B 1 396 ILE 396 395 395 ILE ILE B . n 
B 1 397 ASP 397 396 396 ASP ASP B . n 
B 1 398 HIS 398 397 397 HIS HIS B . n 
B 1 399 ASN 399 398 398 ASN ASN B . n 
B 1 400 GLY 400 399 399 GLY GLY B . n 
B 1 401 ILE 401 400 400 ILE ILE B . n 
B 1 402 PRO 402 401 401 PRO PRO B . n 
B 1 403 LEU 403 402 402 LEU LEU B . n 
B 1 404 ALA 404 403 403 ALA ALA B . n 
B 1 405 GLY 405 404 404 GLY GLY B . n 
B 1 406 GLU 406 405 405 GLU GLU B . n 
B 1 407 PHE 407 406 406 PHE PHE B . n 
B 1 408 ILE 408 407 407 ILE ILE B . n 
B 1 409 GLN 409 408 408 GLN GLN B . n 
B 1 410 LYS 410 409 409 LYS LYS B . n 
B 1 411 SER 411 410 410 SER SER B . n 
B 1 412 GLY 412 411 411 GLY GLY B . n 
B 1 413 LEU 413 412 412 LEU LEU B . n 
B 1 414 ALA 414 413 413 ALA ALA B . n 
B 1 415 ALA 415 414 414 ALA ALA B . n 
B 1 416 GLN 416 415 415 GLN GLN B . n 
B 1 417 GLU 417 416 416 GLU GLU B . n 
B 1 418 TRP 418 417 417 TRP TRP B . n 
B 1 419 LEU 419 418 418 LEU LEU B . n 
B 1 420 ALA 420 419 419 ALA ALA B . n 
B 1 421 ARG 421 420 420 ARG ARG B . n 
B 1 422 TYR 422 421 421 TYR TYR B . n 
B 1 423 LEU 423 422 422 LEU LEU B . n 
B 1 424 ARG 424 423 423 ARG ARG B . n 
B 1 425 ALA 425 424 424 ALA ALA B . n 
B 1 426 TYR 426 425 425 TYR TYR B . n 
B 1 427 LEU 427 426 426 LEU LEU B . n 
B 1 428 HIS 428 427 427 HIS HIS B . n 
B 1 429 PRO 429 428 428 PRO PRO B . n 
B 1 430 ILE 430 429 429 ILE ILE B . n 
B 1 431 ILE 431 430 430 ILE ILE B . n 
B 1 432 TYR 432 431 431 TYR TYR B . n 
B 1 433 LEU 433 432 432 LEU LEU B . n 
B 1 434 LEU 434 433 433 LEU LEU B . n 
B 1 435 TYR 435 434 434 TYR TYR B . n 
B 1 436 ARG 436 435 435 ARG ARG B . n 
B 1 437 TYR 437 436 436 TYR TYR B . n 
B 1 438 GLU 438 437 437 GLU GLU B . n 
B 1 439 PHE 439 438 438 PHE PHE B . n 
B 1 440 LYS 440 439 439 LYS LYS B . n 
B 1 441 PHE 441 440 440 PHE PHE B . n 
B 1 442 SER 442 441 441 SER SER B . n 
B 1 443 PRO 443 442 442 PRO PRO B . n 
B 1 444 HIS 444 443 443 HIS HIS B . n 
B 1 445 GLY 445 444 444 GLY GLY B . n 
B 1 446 GLU 446 445 445 GLU GLU B . n 
B 1 447 ASN 447 446 446 ASN ASN B . n 
B 1 448 LEU 448 447 447 LEU LEU B . n 
B 1 449 ILE 449 448 448 ILE ILE B . n 
B 1 450 LEU 450 449 449 LEU LEU B . n 
B 1 451 VAL 451 450 450 VAL VAL B . n 
B 1 452 LEU 452 451 451 LEU LEU B . n 
B 1 453 ASP 453 452 452 ASP ASP B . n 
B 1 454 GLY 454 453 453 GLY GLY B . n 
B 1 455 GLY 455 454 454 GLY GLY B . n 
B 1 456 ALA 456 455 455 ALA ALA B . n 
B 1 457 PRO 457 456 456 PRO PRO B . n 
B 1 458 VAL 458 457 457 VAL VAL B . n 
B 1 459 ARG 459 458 458 ARG ARG B . n 
B 1 460 ALA 460 459 459 ALA ALA B . n 
B 1 461 VAL 461 460 460 VAL VAL B . n 
B 1 462 LEU 462 461 461 LEU LEU B . n 
B 1 463 LYS 463 462 462 LYS LYS B . n 
B 1 464 ASP 464 463 463 ASP ASP B . n 
B 1 465 ILE 465 464 464 ILE ILE B . n 
B 1 466 GLY 466 465 465 GLY GLY B . n 
B 1 467 GLU 467 466 466 GLU GLU B . n 
B 1 468 GLU 468 467 467 GLU GLU B . n 
B 1 469 ILE 469 468 468 ILE ILE B . n 
B 1 470 CYS 470 469 469 CYS CYS B . n 
B 1 471 ILE 471 470 470 ILE ILE B . n 
B 1 472 PHE 472 471 471 PHE PHE B . n 
B 1 473 ASP 473 472 472 ASP ASP B . n 
B 1 474 ALA 474 473 473 ALA ALA B . n 
B 1 475 PRO 475 474 474 PRO PRO B . n 
B 1 476 ASP 476 475 475 ASP ASP B . n 
B 1 477 ASP 477 476 476 ASP ASP B . n 
B 1 478 ILE 478 477 477 ILE ILE B . n 
B 1 479 PRO 479 478 478 PRO PRO B . n 
B 1 480 GLU 480 479 479 GLU GLU B . n 
B 1 481 SER 481 480 480 SER SER B . n 
B 1 482 CYS 482 481 481 CYS CYS B . n 
B 1 483 ARG 483 482 482 ARG ARG B . n 
B 1 484 ARG 484 483 483 ARG ARG B . n 
B 1 485 ALA 485 484 484 ALA ALA B . n 
B 1 486 VAL 486 485 485 VAL VAL B . n 
B 1 487 THR 487 486 486 THR THR B . n 
B 1 488 GLU 488 487 487 GLU GLU B . n 
B 1 489 GLU 489 488 488 GLU GLU B . n 
B 1 490 ALA 490 489 489 ALA ALA B . n 
B 1 491 ASP 491 490 490 ASP ASP B . n 
B 1 492 GLU 492 491 491 GLU GLU B . n 
B 1 493 ILE 493 492 492 ILE ILE B . n 
B 1 494 ARG 494 493 493 ARG ARG B . n 
B 1 495 ASN 495 494 494 ASN ASN B . n 
B 1 496 LEU 496 495 495 LEU LEU B . n 
B 1 497 GLY 497 496 496 GLY GLY B . n 
B 1 498 VAL 498 497 497 VAL VAL B . n 
B 1 499 LEU 499 498 498 LEU LEU B . n 
B 1 500 SER 500 499 499 SER SER B . n 
B 1 501 ASP 501 500 500 ASP ASP B . n 
B 1 502 VAL 502 501 501 VAL VAL B . n 
B 1 503 PHE 503 502 502 PHE PHE B . n 
B 1 504 ASP 504 503 503 ASP ASP B . n 
B 1 505 ASP 505 504 504 ASP ASP B . n 
B 1 506 PHE 506 505 505 PHE PHE B . n 
B 1 507 LEU 507 506 506 LEU LEU B . n 
B 1 508 ARG 508 507 507 ARG ARG B . n 
B 1 509 HIS 509 508 508 HIS HIS B . n 
B 1 510 PHE 510 509 509 PHE PHE B . n 
B 1 511 ALA 511 510 510 ALA ALA B . n 
B 1 512 LEU 512 511 511 LEU LEU B . n 
B 1 513 LEU 513 512 512 LEU LEU B . n 
B 1 514 LEU 514 513 513 LEU LEU B . n 
B 1 515 HIS 515 514 514 HIS HIS B . n 
B 1 516 GLU 516 515 515 GLU GLU B . n 
B 1 517 SER 517 516 516 SER SER B . n 
B 1 518 GLY 518 517 517 GLY GLY B . n 
B 1 519 LEU 519 518 518 LEU LEU B . n 
B 1 520 LEU 520 519 519 LEU LEU B . n 
B 1 521 THR 521 520 520 THR THR B . n 
B 1 522 ASP 522 521 521 ASP ASP B . n 
B 1 523 GLY 523 522 522 GLY GLY B . n 
B 1 524 GLU 524 523 523 GLU GLU B . n 
B 1 525 PHE 525 524 524 PHE PHE B . n 
B 1 526 TRP 526 525 525 TRP TRP B . n 
B 1 527 ALA 527 526 526 ALA ALA B . n 
B 1 528 THR 528 527 527 THR THR B . n 
B 1 529 VAL 529 528 528 VAL VAL B . n 
B 1 530 ALA 530 529 529 ALA ALA B . n 
B 1 531 HIS 531 530 530 HIS HIS B . n 
B 1 532 SER 532 531 531 SER SER B . n 
B 1 533 VAL 533 532 532 VAL VAL B . n 
B 1 534 ALA 534 533 533 ALA ALA B . n 
B 1 535 GLU 535 534 534 GLU GLU B . n 
B 1 536 PHE 536 535 535 PHE PHE B . n 
B 1 537 GLN 537 536 536 GLN GLN B . n 
B 1 538 ALA 538 537 537 ALA ALA B . n 
B 1 539 ARG 539 538 538 ARG ARG B . n 
B 1 540 HIS 540 539 539 HIS HIS B . n 
B 1 541 PRO 541 540 540 PRO PRO B . n 
B 1 542 ASP 542 541 541 ASP ASP B . n 
B 1 543 LEU 543 542 542 LEU LEU B . n 
B 1 544 ALA 544 543 543 ALA ALA B . n 
B 1 545 ASP 545 544 544 ASP ASP B . n 
B 1 546 ARG 546 545 545 ARG ARG B . n 
B 1 547 PHE 547 546 546 PHE PHE B . n 
B 1 548 ASP 548 547 547 ASP ASP B . n 
B 1 549 GLN 549 548 548 GLN GLN B . n 
B 1 550 TRP 550 549 549 TRP TRP B . n 
B 1 551 ASP 551 550 550 ASP ASP B . n 
B 1 552 LEU 552 551 551 LEU LEU B . n 
B 1 553 PHE 553 552 552 PHE PHE B . n 
B 1 554 ALA 554 553 553 ALA ALA B . n 
B 1 555 PRO 555 554 554 PRO PRO B . n 
B 1 556 THR 556 555 555 THR THR B . n 
B 1 557 PHE 557 556 556 PHE PHE B . n 
B 1 558 PRO 558 557 557 PRO PRO B . n 
B 1 559 ALA 559 558 558 ALA ALA B . n 
B 1 560 ILE 560 559 559 ILE ILE B . n 
B 1 561 HIS 561 560 560 HIS HIS B . n 
B 1 562 MET 562 561 561 MET MET B . n 
B 1 563 ASN 563 562 562 ASN ASN B . n 
B 1 564 ARG 564 563 563 ARG ARG B . n 
B 1 565 LEU 565 564 564 LEU LEU B . n 
B 1 566 GLN 566 565 565 GLN GLN B . n 
B 1 567 LEU 567 566 566 LEU LEU B . n 
B 1 568 SER 568 567 567 SER SER B . n 
B 1 569 ASN 569 568 568 ASN ASN B . n 
B 1 570 ASN 570 569 ?   ?   ?   B . n 
B 1 571 ARG 571 570 ?   ?   ?   B . n 
B 1 572 ARG 572 571 571 ARG ARG B . n 
B 1 573 MET 573 572 572 MET MET B . n 
B 1 574 VAL 574 573 573 VAL VAL B . n 
B 1 575 ASN 575 574 ?   ?   ?   B . n 
B 1 576 LEU 576 575 ?   ?   ?   B . n 
B 1 577 GLY 577 576 ?   ?   ?   B . n 
B 1 578 ASP 578 577 577 ASP ASP B . n 
B 1 579 SER 579 578 578 SER SER B . n 
B 1 580 TYR 580 579 579 TYR TYR B . n 
B 1 581 SER 581 580 580 SER SER B . n 
B 1 582 THR 582 581 581 THR THR B . n 
B 1 583 LEU 583 582 582 LEU LEU B . n 
B 1 584 VAL 584 583 583 VAL VAL B . n 
B 1 585 ASP 585 584 584 ASP ASP B . n 
B 1 586 ASN 586 585 585 ASN ASN B . n 
B 1 587 GLU 587 586 586 GLU GLU B . n 
B 1 588 HIS 588 587 587 HIS HIS B . n 
B 1 589 ALA 589 588 588 ALA ALA B . n 
B 1 590 LEU 590 589 589 LEU LEU B . n 
B 1 591 VAL 591 590 590 VAL VAL B . n 
B 1 592 ASN 592 591 591 ASN ASN B . n 
B 1 593 PRO 593 592 592 PRO PRO B . n 
B 1 594 ILE 594 593 593 ILE ILE B . n 
B 1 595 ALA 595 594 594 ALA ALA B . n 
B 1 596 GLY 596 595 595 GLY GLY B . n 
B 1 597 HIS 597 596 596 HIS HIS B . n 
B 1 598 ARG 598 597 597 ARG ARG B . n 
B 1 599 GLY 599 598 598 GLY GLY B . n 
B 1 600 ALA 600 599 599 ALA ALA B . n 
B 1 601 VAL 601 600 600 VAL VAL B . n 
B 1 602 THR 602 601 ?   ?   ?   B . n 
B 1 603 THR 603 602 ?   ?   ?   B . n 
B 1 604 THR 604 603 ?   ?   ?   B . n 
B 1 605 SER 605 604 ?   ?   ?   B . n 
B 1 606 GLY 606 605 ?   ?   ?   B . n 
B 1 607 ALA 607 606 ?   ?   ?   B . n 
B 1 608 GLU 608 607 ?   ?   ?   B . n 
B 1 609 VAL 609 608 ?   ?   ?   B . n 
B 1 610 HIS 610 609 ?   ?   ?   B . n 
B 1 611 ALA 611 610 ?   ?   ?   B . n 
B 1 612 ALA 612 611 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 MLI 1 701 650 MLI MLI A . 
D 2 MLI 1 701 650 MLI MLI B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 88  ? CG  ? A GLU 89  CG  
2   1 Y 1 A GLU 88  ? CD  ? A GLU 89  CD  
3   1 Y 1 A GLU 88  ? OE1 ? A GLU 89  OE1 
4   1 Y 1 A GLU 88  ? OE2 ? A GLU 89  OE2 
5   1 Y 1 A ARG 91  ? CG  ? A ARG 92  CG  
6   1 Y 1 A ARG 91  ? CD  ? A ARG 92  CD  
7   1 Y 1 A ARG 91  ? NE  ? A ARG 92  NE  
8   1 Y 1 A ARG 91  ? CZ  ? A ARG 92  CZ  
9   1 Y 1 A ARG 91  ? NH1 ? A ARG 92  NH1 
10  1 Y 1 A ARG 91  ? NH2 ? A ARG 92  NH2 
11  1 Y 1 A ASP 110 ? CG  ? A ASP 111 CG  
12  1 Y 1 A ASP 110 ? OD1 ? A ASP 111 OD1 
13  1 Y 1 A ASP 110 ? OD2 ? A ASP 111 OD2 
14  1 Y 1 A GLU 114 ? CG  ? A GLU 115 CG  
15  1 Y 1 A GLU 114 ? CD  ? A GLU 115 CD  
16  1 Y 1 A GLU 114 ? OE1 ? A GLU 115 OE1 
17  1 Y 1 A GLU 114 ? OE2 ? A GLU 115 OE2 
18  1 Y 1 A GLU 139 ? CG  ? A GLU 140 CG  
19  1 Y 1 A GLU 139 ? CD  ? A GLU 140 CD  
20  1 Y 1 A GLU 139 ? OE1 ? A GLU 140 OE1 
21  1 Y 1 A GLU 139 ? OE2 ? A GLU 140 OE2 
22  1 Y 1 A GLU 205 ? CG  ? A GLU 206 CG  
23  1 Y 1 A GLU 205 ? CD  ? A GLU 206 CD  
24  1 Y 1 A GLU 205 ? OE1 ? A GLU 206 OE1 
25  1 Y 1 A GLU 205 ? OE2 ? A GLU 206 OE2 
26  1 Y 1 A ARG 224 ? CG  ? A ARG 225 CG  
27  1 Y 1 A ARG 224 ? CD  ? A ARG 225 CD  
28  1 Y 1 A ARG 224 ? NE  ? A ARG 225 NE  
29  1 Y 1 A ARG 224 ? CZ  ? A ARG 225 CZ  
30  1 Y 1 A ARG 224 ? NH1 ? A ARG 225 NH1 
31  1 Y 1 A ARG 224 ? NH2 ? A ARG 225 NH2 
32  1 Y 1 A ARG 359 ? CG  ? A ARG 360 CG  
33  1 Y 1 A ARG 359 ? CD  ? A ARG 360 CD  
34  1 Y 1 A ARG 359 ? NE  ? A ARG 360 NE  
35  1 Y 1 A ARG 359 ? CZ  ? A ARG 360 CZ  
36  1 Y 1 A ARG 359 ? NH1 ? A ARG 360 NH1 
37  1 Y 1 A ARG 359 ? NH2 ? A ARG 360 NH2 
38  1 Y 1 A GLU 466 ? CG  ? A GLU 467 CG  
39  1 Y 1 A GLU 466 ? CD  ? A GLU 467 CD  
40  1 Y 1 A GLU 466 ? OE1 ? A GLU 467 OE1 
41  1 Y 1 A GLU 466 ? OE2 ? A GLU 467 OE2 
42  1 Y 1 A ILE 477 ? CG1 ? A ILE 478 CG1 
43  1 Y 1 A ILE 477 ? CG2 ? A ILE 478 CG2 
44  1 Y 1 A ILE 477 ? CD1 ? A ILE 478 CD1 
45  1 Y 1 A GLU 479 ? CG  ? A GLU 480 CG  
46  1 Y 1 A GLU 479 ? CD  ? A GLU 480 CD  
47  1 Y 1 A GLU 479 ? OE1 ? A GLU 480 OE1 
48  1 Y 1 A GLU 479 ? OE2 ? A GLU 480 OE2 
49  1 Y 1 A ARG 482 ? CG  ? A ARG 483 CG  
50  1 Y 1 A ARG 482 ? CD  ? A ARG 483 CD  
51  1 Y 1 A ARG 482 ? NE  ? A ARG 483 NE  
52  1 Y 1 A ARG 482 ? CZ  ? A ARG 483 CZ  
53  1 Y 1 A ARG 482 ? NH1 ? A ARG 483 NH1 
54  1 Y 1 A ARG 482 ? NH2 ? A ARG 483 NH2 
55  1 Y 1 A THR 486 ? OG1 ? A THR 487 OG1 
56  1 Y 1 A THR 486 ? CG2 ? A THR 487 CG2 
57  1 Y 1 A GLU 487 ? CG  ? A GLU 488 CG  
58  1 Y 1 A GLU 487 ? CD  ? A GLU 488 CD  
59  1 Y 1 A GLU 487 ? OE1 ? A GLU 488 OE1 
60  1 Y 1 A GLU 487 ? OE2 ? A GLU 488 OE2 
61  1 Y 1 A GLU 491 ? CG  ? A GLU 492 CG  
62  1 Y 1 A GLU 491 ? CD  ? A GLU 492 CD  
63  1 Y 1 A GLU 491 ? OE1 ? A GLU 492 OE1 
64  1 Y 1 A GLU 491 ? OE2 ? A GLU 492 OE2 
65  1 Y 1 A TYR 579 ? CG  ? A TYR 580 CG  
66  1 Y 1 A TYR 579 ? CD1 ? A TYR 580 CD1 
67  1 Y 1 A TYR 579 ? CD2 ? A TYR 580 CD2 
68  1 Y 1 A TYR 579 ? CE1 ? A TYR 580 CE1 
69  1 Y 1 A TYR 579 ? CE2 ? A TYR 580 CE2 
70  1 Y 1 A TYR 579 ? CZ  ? A TYR 580 CZ  
71  1 Y 1 A TYR 579 ? OH  ? A TYR 580 OH  
72  1 Y 1 A VAL 583 ? CG1 ? A VAL 584 CG1 
73  1 Y 1 A VAL 583 ? CG2 ? A VAL 584 CG2 
74  1 Y 1 A GLU 586 ? CG  ? A GLU 587 CG  
75  1 Y 1 A GLU 586 ? CD  ? A GLU 587 CD  
76  1 Y 1 A GLU 586 ? OE1 ? A GLU 587 OE1 
77  1 Y 1 A GLU 586 ? OE2 ? A GLU 587 OE2 
78  1 Y 1 A ARG 597 ? CG  ? A ARG 598 CG  
79  1 Y 1 A ARG 597 ? CD  ? A ARG 598 CD  
80  1 Y 1 A ARG 597 ? NE  ? A ARG 598 NE  
81  1 Y 1 A ARG 597 ? CZ  ? A ARG 598 CZ  
82  1 Y 1 A ARG 597 ? NH1 ? A ARG 598 NH1 
83  1 Y 1 A ARG 597 ? NH2 ? A ARG 598 NH2 
84  1 Y 1 B ARG 42  ? CG  ? B ARG 43  CG  
85  1 Y 1 B ARG 42  ? CD  ? B ARG 43  CD  
86  1 Y 1 B ARG 42  ? NE  ? B ARG 43  NE  
87  1 Y 1 B ARG 42  ? CZ  ? B ARG 43  CZ  
88  1 Y 1 B ARG 42  ? NH1 ? B ARG 43  NH1 
89  1 Y 1 B ARG 42  ? NH2 ? B ARG 43  NH2 
90  1 Y 1 B GLU 59  ? CG  ? B GLU 60  CG  
91  1 Y 1 B GLU 59  ? CD  ? B GLU 60  CD  
92  1 Y 1 B GLU 59  ? OE1 ? B GLU 60  OE1 
93  1 Y 1 B GLU 59  ? OE2 ? B GLU 60  OE2 
94  1 Y 1 B ARG 63  ? CG  ? B ARG 64  CG  
95  1 Y 1 B ARG 63  ? CD  ? B ARG 64  CD  
96  1 Y 1 B ARG 63  ? NE  ? B ARG 64  NE  
97  1 Y 1 B ARG 63  ? CZ  ? B ARG 64  CZ  
98  1 Y 1 B ARG 63  ? NH1 ? B ARG 64  NH1 
99  1 Y 1 B ARG 63  ? NH2 ? B ARG 64  NH2 
100 1 Y 1 B ARG 82  ? CG  ? B ARG 83  CG  
101 1 Y 1 B ARG 82  ? CD  ? B ARG 83  CD  
102 1 Y 1 B ARG 82  ? NE  ? B ARG 83  NE  
103 1 Y 1 B ARG 82  ? CZ  ? B ARG 83  CZ  
104 1 Y 1 B ARG 82  ? NH1 ? B ARG 83  NH1 
105 1 Y 1 B ARG 82  ? NH2 ? B ARG 83  NH2 
106 1 Y 1 B ARG 85  ? CG  ? B ARG 86  CG  
107 1 Y 1 B ARG 85  ? CD  ? B ARG 86  CD  
108 1 Y 1 B ARG 85  ? NE  ? B ARG 86  NE  
109 1 Y 1 B ARG 85  ? CZ  ? B ARG 86  CZ  
110 1 Y 1 B ARG 85  ? NH1 ? B ARG 86  NH1 
111 1 Y 1 B ARG 85  ? NH2 ? B ARG 86  NH2 
112 1 Y 1 B LYS 86  ? CG  ? B LYS 87  CG  
113 1 Y 1 B LYS 86  ? CD  ? B LYS 87  CD  
114 1 Y 1 B LYS 86  ? CE  ? B LYS 87  CE  
115 1 Y 1 B LYS 86  ? NZ  ? B LYS 87  NZ  
116 1 Y 1 B GLU 88  ? CG  ? B GLU 89  CG  
117 1 Y 1 B GLU 88  ? CD  ? B GLU 89  CD  
118 1 Y 1 B GLU 88  ? OE1 ? B GLU 89  OE1 
119 1 Y 1 B GLU 88  ? OE2 ? B GLU 89  OE2 
120 1 Y 1 B GLU 89  ? CG  ? B GLU 90  CG  
121 1 Y 1 B GLU 89  ? CD  ? B GLU 90  CD  
122 1 Y 1 B GLU 89  ? OE1 ? B GLU 90  OE1 
123 1 Y 1 B GLU 89  ? OE2 ? B GLU 90  OE2 
124 1 Y 1 B ASP 110 ? CG  ? B ASP 111 CG  
125 1 Y 1 B ASP 110 ? OD1 ? B ASP 111 OD1 
126 1 Y 1 B ASP 110 ? OD2 ? B ASP 111 OD2 
127 1 Y 1 B GLU 205 ? CG  ? B GLU 206 CG  
128 1 Y 1 B GLU 205 ? CD  ? B GLU 206 CD  
129 1 Y 1 B GLU 205 ? OE1 ? B GLU 206 OE1 
130 1 Y 1 B GLU 205 ? OE2 ? B GLU 206 OE2 
131 1 Y 1 B ARG 211 ? CG  ? B ARG 212 CG  
132 1 Y 1 B ARG 211 ? CD  ? B ARG 212 CD  
133 1 Y 1 B ARG 211 ? NE  ? B ARG 212 NE  
134 1 Y 1 B ARG 211 ? CZ  ? B ARG 212 CZ  
135 1 Y 1 B ARG 211 ? NH1 ? B ARG 212 NH1 
136 1 Y 1 B ARG 211 ? NH2 ? B ARG 212 NH2 
137 1 Y 1 B ARG 326 ? CG  ? B ARG 327 CG  
138 1 Y 1 B ARG 326 ? CD  ? B ARG 327 CD  
139 1 Y 1 B ARG 326 ? NE  ? B ARG 327 NE  
140 1 Y 1 B ARG 326 ? CZ  ? B ARG 327 CZ  
141 1 Y 1 B ARG 326 ? NH1 ? B ARG 327 NH1 
142 1 Y 1 B ARG 326 ? NH2 ? B ARG 327 NH2 
143 1 Y 1 B ARG 359 ? CG  ? B ARG 360 CG  
144 1 Y 1 B ARG 359 ? CD  ? B ARG 360 CD  
145 1 Y 1 B ARG 359 ? NE  ? B ARG 360 NE  
146 1 Y 1 B ARG 359 ? CZ  ? B ARG 360 CZ  
147 1 Y 1 B ARG 359 ? NH1 ? B ARG 360 NH1 
148 1 Y 1 B ARG 359 ? NH2 ? B ARG 360 NH2 
149 1 Y 1 B GLU 382 ? CG  ? B GLU 383 CG  
150 1 Y 1 B GLU 382 ? CD  ? B GLU 383 CD  
151 1 Y 1 B GLU 382 ? OE1 ? B GLU 383 OE1 
152 1 Y 1 B GLU 382 ? OE2 ? B GLU 383 OE2 
153 1 Y 1 B GLU 479 ? CG  ? B GLU 480 CG  
154 1 Y 1 B GLU 479 ? CD  ? B GLU 480 CD  
155 1 Y 1 B GLU 479 ? OE1 ? B GLU 480 OE1 
156 1 Y 1 B GLU 479 ? OE2 ? B GLU 480 OE2 
157 1 Y 1 B ARG 482 ? CG  ? B ARG 483 CG  
158 1 Y 1 B ARG 482 ? CD  ? B ARG 483 CD  
159 1 Y 1 B ARG 482 ? NE  ? B ARG 483 NE  
160 1 Y 1 B ARG 482 ? CZ  ? B ARG 483 CZ  
161 1 Y 1 B ARG 482 ? NH1 ? B ARG 483 NH1 
162 1 Y 1 B ARG 482 ? NH2 ? B ARG 483 NH2 
163 1 Y 1 B GLU 487 ? CG  ? B GLU 488 CG  
164 1 Y 1 B GLU 487 ? CD  ? B GLU 488 CD  
165 1 Y 1 B GLU 487 ? OE1 ? B GLU 488 OE1 
166 1 Y 1 B GLU 487 ? OE2 ? B GLU 488 OE2 
167 1 Y 1 B GLU 491 ? CG  ? B GLU 492 CG  
168 1 Y 1 B GLU 491 ? CD  ? B GLU 492 CD  
169 1 Y 1 B GLU 491 ? OE1 ? B GLU 492 OE1 
170 1 Y 1 B GLU 491 ? OE2 ? B GLU 492 OE2 
171 1 Y 1 B ASN 568 ? CG  ? B ASN 569 CG  
172 1 Y 1 B ASN 568 ? OD1 ? B ASN 569 OD1 
173 1 Y 1 B ASN 568 ? ND2 ? B ASN 569 ND2 
174 1 Y 1 B ARG 571 ? CG  ? B ARG 572 CG  
175 1 Y 1 B ARG 571 ? CD  ? B ARG 572 CD  
176 1 Y 1 B ARG 571 ? NE  ? B ARG 572 NE  
177 1 Y 1 B ARG 571 ? CZ  ? B ARG 572 CZ  
178 1 Y 1 B ARG 571 ? NH1 ? B ARG 572 NH1 
179 1 Y 1 B ARG 571 ? NH2 ? B ARG 572 NH2 
180 1 Y 1 B ASP 577 ? CG  ? B ASP 578 CG  
181 1 Y 1 B ASP 577 ? OD1 ? B ASP 578 OD1 
182 1 Y 1 B ASP 577 ? OD2 ? B ASP 578 OD2 
183 1 Y 1 B SER 578 ? OG  ? B SER 579 OG  
184 1 Y 1 B ASN 585 ? CG  ? B ASN 586 CG  
185 1 Y 1 B ASN 585 ? OD1 ? B ASN 586 OD1 
186 1 Y 1 B ASN 585 ? ND2 ? B ASN 586 ND2 
187 1 Y 1 B VAL 600 ? CG1 ? B VAL 601 CG1 
188 1 Y 1 B VAL 600 ? CG2 ? B VAL 601 CG2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NOM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     84.544 
_cell.length_a_esd                 ? 
_cell.length_b                     118.806 
_cell.length_b_esd                 ? 
_cell.length_c                     168.202 
_cell.length_c_esd                 ? 
_cell.volume                       1689477.146 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NOM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NOM 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.07 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          59.96 
_exptl_crystal.description                  'Rod-shaped crystals' 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '1.6 M Sodium malonate and 0.1 M bis-tris propane pH 7 adjusted by HCl (16.35 mg/ml protein)' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     113 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-08-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          52.95 
_reflns.entry_id                                       9NOM 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.87 
_reflns.d_resolution_low                               50.7 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     39480 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.136 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.937 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.325 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.87 
_reflns_shell.d_res_low                                     2.99 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4402 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.539 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.654 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.325 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               48.22 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NOM 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.87 
_refine.ls_d_res_low                             50.70 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     39394 
_refine.ls_number_reflns_R_free                  3784 
_refine.ls_number_reflns_R_work                  70852 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.72 
_refine.ls_percent_reflns_R_free                 5.07 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2059 
_refine.ls_R_factor_R_free                       0.2606 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2029 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.4453 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4037 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.87 
_refine_hist.d_res_low                        50.70 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               9017 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        9003 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         14 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0083 ? 9244  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0385 ? 12594 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0546 ? 1409  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0093 ? 1641  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 6.3524 ? 1288  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.87 2.91  . . 126 2664 99.61  . . . . 0.3277 . . . . . . . . . . . . . . . 0.3991 
'X-RAY DIFFRACTION' 2.91 2.94  . . 163 2591 99.71  . . . . 0.3168 . . . . . . . . . . . . . . . 0.3886 
'X-RAY DIFFRACTION' 2.94 2.98  . . 132 2634 99.78  . . . . 0.3008 . . . . . . . . . . . . . . . 0.3161 
'X-RAY DIFFRACTION' 2.98 3.03  . . 143 2628 99.64  . . . . 0.2880 . . . . . . . . . . . . . . . 0.3986 
'X-RAY DIFFRACTION' 3.03 3.07  . . 142 2597 99.75  . . . . 0.2746 . . . . . . . . . . . . . . . 0.3171 
'X-RAY DIFFRACTION' 3.07 3.12  . . 128 2661 99.82  . . . . 0.2635 . . . . . . . . . . . . . . . 0.3535 
'X-RAY DIFFRACTION' 3.12 3.17  . . 133 2630 99.78  . . . . 0.2547 . . . . . . . . . . . . . . . 0.2770 
'X-RAY DIFFRACTION' 3.17 3.23  . . 130 2663 99.86  . . . . 0.2549 . . . . . . . . . . . . . . . 0.3381 
'X-RAY DIFFRACTION' 3.23 3.29  . . 144 2574 99.96  . . . . 0.2444 . . . . . . . . . . . . . . . 0.2971 
'X-RAY DIFFRACTION' 3.29 3.35  . . 144 2603 99.96  . . . . 0.2435 . . . . . . . . . . . . . . . 0.2666 
'X-RAY DIFFRACTION' 3.35 3.42  . . 140 2669 99.93  . . . . 0.2366 . . . . . . . . . . . . . . . 0.3007 
'X-RAY DIFFRACTION' 3.42 3.49  . . 136 2649 99.86  . . . . 0.2267 . . . . . . . . . . . . . . . 0.2990 
'X-RAY DIFFRACTION' 3.49 3.57  . . 135 2597 99.71  . . . . 0.2094 . . . . . . . . . . . . . . . 0.2793 
'X-RAY DIFFRACTION' 3.57 3.66  . . 133 2646 98.97  . . . . 0.2095 . . . . . . . . . . . . . . . 0.2493 
'X-RAY DIFFRACTION' 3.66 3.76  . . 135 2618 99.96  . . . . 0.1996 . . . . . . . . . . . . . . . 0.2566 
'X-RAY DIFFRACTION' 3.76 3.87  . . 155 2610 99.96  . . . . 0.1881 . . . . . . . . . . . . . . . 0.2721 
'X-RAY DIFFRACTION' 3.87 4.00  . . 111 2667 99.93  . . . . 0.1877 . . . . . . . . . . . . . . . 0.2381 
'X-RAY DIFFRACTION' 4.00 4.14  . . 146 2604 99.96  . . . . 0.1767 . . . . . . . . . . . . . . . 0.2315 
'X-RAY DIFFRACTION' 4.14 4.30  . . 157 2623 99.93  . . . . 0.1823 . . . . . . . . . . . . . . . 0.2099 
'X-RAY DIFFRACTION' 4.30 4.50  . . 131 2627 99.93  . . . . 0.1602 . . . . . . . . . . . . . . . 0.2339 
'X-RAY DIFFRACTION' 4.50 4.74  . . 163 2625 99.75  . . . . 0.1560 . . . . . . . . . . . . . . . 0.2549 
'X-RAY DIFFRACTION' 4.74 5.03  . . 141 2635 100.00 . . . . 0.1665 . . . . . . . . . . . . . . . 0.2299 
'X-RAY DIFFRACTION' 5.03 5.42  . . 131 2625 98.71  . . . . 0.1878 . . . . . . . . . . . . . . . 0.2873 
'X-RAY DIFFRACTION' 5.42 5.97  . . 152 2578 100.00 . . . . 0.1994 . . . . . . . . . . . . . . . 0.2854 
'X-RAY DIFFRACTION' 5.97 6.83  . . 149 2627 100.00 . . . . 0.1985 . . . . . . . . . . . . . . . 0.2691 
'X-RAY DIFFRACTION' 6.83 8.59  . . 159 2634 99.96  . . . . 0.1740 . . . . . . . . . . . . . . . 0.1940 
'X-RAY DIFFRACTION' 8.60 50.70 . . 125 2573 97.97  . . . . 0.1604 . . . . . . . . . . . . . . . 0.1716 
# 
_struct.entry_id                     9NOM 
_struct.title                        'Structure of the NIS synthetase NcdF from nocardichelin biosynthesis' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NOM 
_struct_keywords.text            'NIS synthetase, siderophore biosynthesis, NRPS independent siderophores, NcdF, LIGASE' 
_struct_keywords.pdbx_keywords   LIGASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9NOM 
_struct_ref.pdbx_db_accession          9NOM 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NOM A 1 ? 612 ? 9NOM 0 ? 611 ? 0 611 
2 1 9NOM B 1 ? 612 ? 9NOM 0 ? 611 ? 0 611 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C 
2 1 B,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 TYR A 20  ? GLU A 39  ? TYR A 19  GLU A 38  1 ? 20 
HELX_P HELX_P2  AA2 ALA A 79  ? LEU A 82  ? ALA A 78  LEU A 81  5 ? 4  
HELX_P HELX_P3  AA3 ASP A 94  ? SER A 103 ? ASP A 93  SER A 102 1 ? 10 
HELX_P HELX_P4  AA4 ALA A 112 ? ASP A 129 ? ALA A 111 ASP A 128 1 ? 18 
HELX_P HELX_P5  AA5 PRO A 137 ? ALA A 142 ? PRO A 136 ALA A 141 1 ? 6  
HELX_P HELX_P6  AA6 ASP A 145 ? MET A 153 ? ASP A 144 MET A 152 1 ? 9  
HELX_P HELX_P7  AA7 SER A 170 ? ALA A 178 ? SER A 169 ALA A 177 1 ? 9  
HELX_P HELX_P8  AA8 PRO A 179 ? GLY A 182 ? PRO A 178 GLY A 181 5 ? 4  
HELX_P HELX_P9  AA9 GLU A 206 ? ARG A 230 ? GLU A 205 ARG A 229 1 ? 25 
HELX_P HELX_P10 AB1 HIS A 243 ? LYS A 250 ? HIS A 242 LYS A 249 1 ? 8  
HELX_P HELX_P11 AB2 LYS A 250 ? TYR A 255 ? LYS A 249 TYR A 254 1 ? 6  
HELX_P HELX_P12 AB3 TYR A 255 ? GLU A 261 ? TYR A 254 GLU A 260 1 ? 7  
HELX_P HELX_P13 AB4 SER A 310 ? HIS A 329 ? SER A 309 HIS A 328 1 ? 20 
HELX_P HELX_P14 AB5 ASP A 331 ? GLY A 338 ? ASP A 330 GLY A 337 1 ? 8  
HELX_P HELX_P15 AB6 ASN A 352 ? ILE A 358 ? ASN A 351 ILE A 357 1 ? 7  
HELX_P HELX_P16 AB7 SER A 363 ? LYS A 367 ? SER A 362 LYS A 366 5 ? 5  
HELX_P HELX_P17 AB8 PRO A 377 ? VAL A 381 ? PRO A 376 VAL A 380 5 ? 5  
HELX_P HELX_P18 AB9 ALA A 391 ? HIS A 395 ? ALA A 390 HIS A 394 5 ? 5  
HELX_P HELX_P19 AC1 PRO A 402 ? SER A 411 ? PRO A 401 SER A 410 1 ? 10 
HELX_P HELX_P20 AC2 ALA A 414 ? ARG A 436 ? ALA A 413 ARG A 435 1 ? 23 
HELX_P HELX_P21 AC3 PRO A 479 ? VAL A 486 ? PRO A 478 VAL A 485 5 ? 8  
HELX_P HELX_P22 AC4 ALA A 490 ? ARG A 494 ? ALA A 489 ARG A 493 5 ? 5  
HELX_P HELX_P23 AC5 ASN A 495 ? SER A 500 ? ASN A 494 SER A 499 1 ? 6  
HELX_P HELX_P24 AC6 PHE A 506 ? SER A 517 ? PHE A 505 SER A 516 1 ? 12 
HELX_P HELX_P25 AC7 THR A 521 ? HIS A 540 ? THR A 520 HIS A 539 1 ? 20 
HELX_P HELX_P26 AC8 LEU A 543 ? TRP A 550 ? LEU A 542 TRP A 549 1 ? 8  
HELX_P HELX_P27 AC9 HIS A 561 ? LEU A 567 ? HIS A 560 LEU A 566 1 ? 7  
HELX_P HELX_P28 AD1 SER A 579 ? LEU A 583 ? SER A 578 LEU A 582 5 ? 5  
HELX_P HELX_P29 AD2 PRO A 593 ? ARG A 598 ? PRO A 592 ARG A 597 5 ? 6  
HELX_P HELX_P30 AD3 TYR B 20  ? GLU B 39  ? TYR B 19  GLU B 38  1 ? 20 
HELX_P HELX_P31 AD4 ASP B 78  ? LEU B 82  ? ASP B 77  LEU B 81  5 ? 5  
HELX_P HELX_P32 AD5 ASP B 94  ? MET B 102 ? ASP B 93  MET B 101 1 ? 9  
HELX_P HELX_P33 AD6 PRO B 109 ? ASP B 111 ? PRO B 108 ASP B 110 5 ? 3  
HELX_P HELX_P34 AD7 ALA B 112 ? ASP B 129 ? ALA B 111 ASP B 128 1 ? 18 
HELX_P HELX_P35 AD8 PRO B 131 ? ARG B 135 ? PRO B 130 ARG B 134 5 ? 5  
HELX_P HELX_P36 AD9 PRO B 137 ? VAL B 143 ? PRO B 136 VAL B 142 1 ? 7  
HELX_P HELX_P37 AE1 ASP B 145 ? MET B 153 ? ASP B 144 MET B 152 1 ? 9  
HELX_P HELX_P38 AE2 SER B 170 ? ALA B 178 ? SER B 169 ALA B 177 1 ? 9  
HELX_P HELX_P39 AE3 PRO B 179 ? GLY B 182 ? PRO B 178 GLY B 181 5 ? 4  
HELX_P HELX_P40 AE4 GLU B 206 ? GLY B 216 ? GLU B 205 GLY B 215 1 ? 11 
HELX_P HELX_P41 AE5 GLY B 216 ? GLY B 229 ? GLY B 215 GLY B 228 1 ? 14 
HELX_P HELX_P42 AE6 ASP B 233 ? ALA B 235 ? ASP B 232 ALA B 234 5 ? 3  
HELX_P HELX_P43 AE7 HIS B 243 ? LYS B 250 ? HIS B 242 LYS B 249 1 ? 8  
HELX_P HELX_P44 AE8 LYS B 250 ? TYR B 255 ? LYS B 249 TYR B 254 1 ? 6  
HELX_P HELX_P45 AE9 TYR B 255 ? GLU B 261 ? TYR B 254 GLU B 260 1 ? 7  
HELX_P HELX_P46 AF1 SER B 310 ? HIS B 329 ? SER B 309 HIS B 328 1 ? 20 
HELX_P HELX_P47 AF2 ASP B 331 ? GLY B 338 ? ASP B 330 GLY B 337 1 ? 8  
HELX_P HELX_P48 AF3 ASN B 352 ? ILE B 358 ? ASN B 351 ILE B 357 1 ? 7  
HELX_P HELX_P49 AF4 SER B 363 ? LYS B 367 ? SER B 362 LYS B 366 5 ? 5  
HELX_P HELX_P50 AF5 PRO B 377 ? VAL B 381 ? PRO B 376 VAL B 380 5 ? 5  
HELX_P HELX_P51 AF6 ALA B 391 ? HIS B 395 ? ALA B 390 HIS B 394 5 ? 5  
HELX_P HELX_P52 AF7 PRO B 402 ? GLY B 412 ? PRO B 401 GLY B 411 1 ? 11 
HELX_P HELX_P53 AF8 ALA B 414 ? TYR B 437 ? ALA B 413 TYR B 436 1 ? 24 
HELX_P HELX_P54 AF9 PRO B 479 ? ARG B 483 ? PRO B 478 ARG B 482 5 ? 5  
HELX_P HELX_P55 AG1 ALA B 490 ? ARG B 494 ? ALA B 489 ARG B 493 5 ? 5  
HELX_P HELX_P56 AG2 ASN B 495 ? SER B 500 ? ASN B 494 SER B 499 1 ? 6  
HELX_P HELX_P57 AG3 PHE B 506 ? SER B 517 ? PHE B 505 SER B 516 1 ? 12 
HELX_P HELX_P58 AG4 THR B 521 ? HIS B 540 ? THR B 520 HIS B 539 1 ? 20 
HELX_P HELX_P59 AG5 LEU B 543 ? TRP B 550 ? LEU B 542 TRP B 549 1 ? 8  
HELX_P HELX_P60 AG6 HIS B 561 ? LEU B 567 ? HIS B 560 LEU B 566 1 ? 7  
HELX_P HELX_P61 AG7 SER B 579 ? VAL B 584 ? SER B 578 VAL B 583 1 ? 6  
HELX_P HELX_P62 AG8 ILE B 594 ? ARG B 598 ? ILE B 593 ARG B 597 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 6 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 5 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 6 ? 
AB4 ? 2 ? 
AB5 ? 4 ? 
AB6 ? 2 ? 
AB7 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 45  ? SER A 48  ? THR A 44  SER A 47  
AA1 2 ARG A 51  ? HIS A 55  ? ARG A 50  HIS A 54  
AA1 3 THR A 61  ? LEU A 70  ? THR A 60  LEU A 69  
AA1 4 SER A 74  ? ILE A 77  ? SER A 73  ILE A 76  
AA2 1 THR A 45  ? SER A 48  ? THR A 44  SER A 47  
AA2 2 ARG A 51  ? HIS A 55  ? ARG A 50  HIS A 54  
AA2 3 THR A 61  ? LEU A 70  ? THR A 60  LEU A 69  
AA2 4 ARG A 83  ? ARG A 86  ? ARG A 82  ARG A 85  
AA2 5 GLU A 89  ? LEU A 91  ? GLU A 88  LEU A 90  
AA3 1 TYR A 237 ? VAL A 242 ? TYR A 236 VAL A 241 
AA3 2 GLU A 188 ? LEU A 193 ? GLU A 187 LEU A 192 
AA3 3 ILE A 264 ? ALA A 269 ? ILE A 263 ALA A 268 
AA4 1 THR A 197 ? ALA A 201 ? THR A 196 ALA A 200 
AA4 2 GLU A 344 ? TYR A 350 ? GLU A 343 TYR A 349 
AA4 3 SER A 370 ? ARG A 374 ? SER A 369 ARG A 373 
AA4 4 TYR A 293 ? THR A 296 ? TYR A 292 THR A 295 
AA4 5 THR A 282 ? ASN A 285 ? THR A 281 ASN A 284 
AA4 6 TYR A 274 ? PRO A 276 ? TYR A 273 PRO A 275 
AA5 1 LEU A 298 ? ASN A 302 ? LEU A 297 ASN A 301 
AA5 2 PHE A 305 ? ARG A 307 ? PHE A 304 ARG A 306 
AA6 1 GLU A 340 ? MET A 341 ? GLU A 339 MET A 340 
AA6 2 ALA A 456 ? LEU A 462 ? ALA A 455 LEU A 461 
AA6 3 LEU A 448 ? ASP A 453 ? LEU A 447 ASP A 452 
AA6 4 GLU A 385 ? THR A 389 ? GLU A 384 THR A 388 
AA7 1 PHE A 439 ? LYS A 440 ? PHE A 438 LYS A 439 
AA7 2 CYS A 470 ? ILE A 471 ? CYS A 469 ILE A 470 
AA8 1 THR A 556 ? PRO A 558 ? THR A 555 PRO A 557 
AA8 2 ALA A 589 ? VAL A 591 ? ALA A 588 VAL A 590 
AA9 1 THR B 45  ? GLU B 46  ? THR B 44  GLU B 45  
AA9 2 TYR B 52  ? HIS B 55  ? TYR B 51  HIS B 54  
AA9 3 THR B 61  ? PHE B 65  ? THR B 60  PHE B 64  
AA9 4 ARG B 83  ? ARG B 86  ? ARG B 82  ARG B 85  
AA9 5 GLU B 89  ? LEU B 91  ? GLU B 88  LEU B 90  
AB1 1 ILE B 69  ? LEU B 70  ? ILE B 68  LEU B 69  
AB1 2 SER B 74  ? TRP B 75  ? SER B 73  TRP B 74  
AB2 1 TYR B 237 ? VAL B 242 ? TYR B 236 VAL B 241 
AB2 2 GLU B 188 ? LEU B 193 ? GLU B 187 LEU B 192 
AB2 3 ILE B 264 ? ALA B 269 ? ILE B 263 ALA B 268 
AB3 1 THR B 197 ? ALA B 201 ? THR B 196 ALA B 200 
AB3 2 GLU B 344 ? TYR B 350 ? GLU B 343 TYR B 349 
AB3 3 SER B 370 ? ARG B 374 ? SER B 369 ARG B 373 
AB3 4 TYR B 293 ? THR B 296 ? TYR B 292 THR B 295 
AB3 5 THR B 282 ? ASN B 285 ? THR B 281 ASN B 284 
AB3 6 TYR B 274 ? PRO B 276 ? TYR B 273 PRO B 275 
AB4 1 VAL B 301 ? ASN B 302 ? VAL B 300 ASN B 301 
AB4 2 PHE B 305 ? THR B 306 ? PHE B 304 THR B 305 
AB5 1 GLU B 340 ? MET B 341 ? GLU B 339 MET B 340 
AB5 2 ALA B 456 ? LEU B 462 ? ALA B 455 LEU B 461 
AB5 3 LEU B 448 ? ASP B 453 ? LEU B 447 ASP B 452 
AB5 4 GLU B 385 ? THR B 389 ? GLU B 384 THR B 388 
AB6 1 PHE B 439 ? LYS B 440 ? PHE B 438 LYS B 439 
AB6 2 CYS B 470 ? ILE B 471 ? CYS B 469 ILE B 470 
AB7 1 THR B 556 ? PRO B 558 ? THR B 555 PRO B 557 
AB7 2 ALA B 589 ? VAL B 591 ? ALA B 588 VAL B 590 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 47  ? N LEU A 46  O ARG A 51  ? O ARG A 50  
AA1 2 3 N TYR A 52  ? N TYR A 51  O PHE A 65  ? O PHE A 64  
AA1 3 4 N GLU A 68  ? N GLU A 67  O CYS A 76  ? O CYS A 75  
AA2 1 2 N LEU A 47  ? N LEU A 46  O ARG A 51  ? O ARG A 50  
AA2 2 3 N TYR A 52  ? N TYR A 51  O PHE A 65  ? O PHE A 64  
AA2 3 4 N ARG A 64  ? N ARG A 63  O ARG A 83  ? O ARG A 82  
AA2 4 5 N ARG A 84  ? N ARG A 83  O LEU A 91  ? O LEU A 90  
AA3 1 2 O TYR A 238 ? O TYR A 237 N VAL A 192 ? N VAL A 191 
AA3 2 3 N TRP A 189 ? N TRP A 188 O GLY A 268 ? O GLY A 267 
AA4 1 2 N ASP A 198 ? N ASP A 197 O GLY A 349 ? O GLY A 348 
AA4 2 3 N ILE A 348 ? N ILE A 347 O ALA A 371 ? O ALA A 370 
AA4 3 4 O LEU A 372 ? O LEU A 371 N LYS A 295 ? N LYS A 294 
AA4 4 5 O VAL A 294 ? O VAL A 293 N VAL A 283 ? N VAL A 282 
AA4 5 6 O PHE A 284 ? O PHE A 283 N GLN A 275 ? N GLN A 274 
AA5 1 2 N LEU A 298 ? N LEU A 297 O ARG A 307 ? O ARG A 306 
AA6 1 2 N GLU A 340 ? N GLU A 339 O LEU A 462 ? O LEU A 461 
AA6 2 3 O ALA A 456 ? O ALA A 455 N ASP A 453 ? N ASP A 452 
AA6 3 4 O LEU A 452 ? O LEU A 451 N GLN A 386 ? N GLN A 385 
AA7 1 2 N LYS A 440 ? N LYS A 439 O CYS A 470 ? O CYS A 469 
AA8 1 2 N PHE A 557 ? N PHE A 556 O LEU A 590 ? O LEU A 589 
AA9 1 2 N THR B 45  ? N THR B 44  O VAL B 53  ? O VAL B 52  
AA9 2 3 N VAL B 54  ? N VAL B 53  O TYR B 63  ? O TYR B 62  
AA9 3 4 N GLU B 62  ? N GLU B 61  O VAL B 85  ? O VAL B 84  
AA9 4 5 N ARG B 84  ? N ARG B 83  O LEU B 91  ? O LEU B 90  
AB1 1 2 N LEU B 70  ? N LEU B 69  O SER B 74  ? O SER B 73  
AB2 1 2 O VAL B 242 ? O VAL B 241 N GLU B 188 ? N GLU B 187 
AB2 2 3 N ALA B 191 ? N ALA B 190 O VAL B 265 ? O VAL B 264 
AB3 1 2 N ALA B 200 ? N ALA B 199 O ALA B 347 ? O ALA B 346 
AB3 2 3 N ILE B 348 ? N ILE B 347 O ALA B 371 ? O ALA B 370 
AB3 3 4 O ARG B 374 ? O ARG B 373 N TYR B 293 ? N TYR B 292 
AB3 4 5 O VAL B 294 ? O VAL B 293 N VAL B 283 ? N VAL B 282 
AB3 5 6 O PHE B 284 ? O PHE B 283 N GLN B 275 ? N GLN B 274 
AB4 1 2 N ASN B 302 ? N ASN B 301 O PHE B 305 ? O PHE B 304 
AB5 1 2 N GLU B 340 ? N GLU B 339 O LEU B 462 ? O LEU B 461 
AB5 2 3 O ARG B 459 ? O ARG B 458 N VAL B 451 ? N VAL B 450 
AB5 3 4 O LEU B 450 ? O LEU B 449 N THR B 388 ? N THR B 387 
AB6 1 2 N LYS B 440 ? N LYS B 439 O CYS B 470 ? O CYS B 469 
AB7 1 2 N PHE B 557 ? N PHE B 556 O LEU B 590 ? O LEU B 589 
# 
_pdbx_entry_details.entry_id                   9NOM 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG  B SER 18  ? ? OD2 B ASP 131 ? ? 2.06 
2 1 OD1 B ASP 490 ? ? NE1 B TRP 549 ? ? 2.19 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    ASP 
_pdbx_validate_symm_contact.auth_seq_id_1     452 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    NH2 
_pdbx_validate_symm_contact.auth_asym_id_2    B 
_pdbx_validate_symm_contact.auth_comp_id_2    ARG 
_pdbx_validate_symm_contact.auth_seq_id_2     272 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   4_445 
_pdbx_validate_symm_contact.dist              2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 58  ? ? 54.32   15.40   
2  1 PHE A 145 ? ? -23.23  -61.86  
3  1 LYS A 249 ? ? -125.16 -50.54  
4  1 TYR A 254 ? ? -90.39  33.19   
5  1 GLU A 260 ? ? -69.18  11.90   
6  1 ILE A 279 ? ? 76.50   -53.44  
7  1 TYR A 425 ? ? -123.94 -53.02  
8  1 PHE A 440 ? ? -119.27 -140.24 
9  1 VAL A 457 ? ? -126.41 -57.35  
10 1 ASP A 472 ? ? -152.97 78.84   
11 1 PRO A 474 ? ? -64.64  -175.53 
12 1 THR A 486 ? ? -164.85 106.81  
13 1 PHE A 505 ? ? -132.77 -56.17  
14 1 HIS A 539 ? ? -140.97 58.46   
15 1 LEU A 566 ? ? -78.59  48.45   
16 1 LEU B 46  ? ? -96.57  -97.37  
17 1 ASP B 57  ? ? -66.24  8.48    
18 1 ARG B 58  ? ? 59.27   10.25   
19 1 LEU B 71  ? ? 73.11   44.49   
20 1 ALA B 79  ? ? -68.43  0.13    
21 1 LYS B 86  ? ? 30.40   64.93   
22 1 ARG B 91  ? ? -33.41  129.53  
23 1 SER B 104 ? ? -49.77  -18.62  
24 1 ALA B 163 ? ? -155.60 40.85   
25 1 TYR B 254 ? ? -98.77  32.31   
26 1 ILE B 279 ? ? 77.06   -45.61  
27 1 SER B 298 ? ? -69.45  56.92   
28 1 MET B 302 ? ? 71.85   51.50   
29 1 ARG B 306 ? ? -92.54  33.44   
30 1 HIS B 328 ? ? -52.55  101.79  
31 1 ASP B 330 ? ? -24.78  100.00  
32 1 TYR B 425 ? ? -140.63 -46.02  
33 1 PHE B 440 ? ? -131.29 -135.77 
34 1 LYS B 462 ? ? -130.87 -75.32  
35 1 ILE B 464 ? ? -125.98 -54.65  
36 1 ASP B 472 ? ? -104.41 53.48   
37 1 ALA B 473 ? ? -53.39  99.59   
38 1 SER B 480 ? ? -65.79  12.29   
39 1 PHE B 505 ? ? -144.05 -42.18  
40 1 LEU B 566 ? ? -76.91  33.33   
41 1 SER B 567 ? ? -150.98 -12.58  
42 1 PRO B 592 ? ? -58.80  -6.71   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 0   ? A GLY 1   
2  1 Y 1 A HIS 1   ? A HIS 2   
3  1 Y 1 A MET 2   ? A MET 3   
4  1 Y 1 A SER 3   ? A SER 4   
5  1 Y 1 A ILE 4   ? A ILE 5   
6  1 Y 1 A ASP 5   ? A ASP 6   
7  1 Y 1 A ILE 6   ? A ILE 7   
8  1 Y 1 A ARG 7   ? A ARG 8   
9  1 Y 1 A GLY 8   ? A GLY 9   
10 1 Y 1 A ALA 9   ? A ALA 10  
11 1 Y 1 A THR 10  ? A THR 11  
12 1 Y 1 A GLU 11  ? A GLU 12  
13 1 Y 1 A VAL 12  ? A VAL 13  
14 1 Y 1 A PRO 13  ? A PRO 14  
15 1 Y 1 A ALA 14  ? A ALA 15  
16 1 Y 1 A PRO 15  ? A PRO 16  
17 1 Y 1 A ASN 568 ? A ASN 569 
18 1 Y 1 A ASN 569 ? A ASN 570 
19 1 Y 1 A ARG 570 ? A ARG 571 
20 1 Y 1 A ARG 571 ? A ARG 572 
21 1 Y 1 A ASN 574 ? A ASN 575 
22 1 Y 1 A LEU 575 ? A LEU 576 
23 1 Y 1 A GLY 576 ? A GLY 577 
24 1 Y 1 A ASP 577 ? A ASP 578 
25 1 Y 1 A GLY 598 ? A GLY 599 
26 1 Y 1 A ALA 599 ? A ALA 600 
27 1 Y 1 A VAL 600 ? A VAL 601 
28 1 Y 1 A THR 601 ? A THR 602 
29 1 Y 1 A THR 602 ? A THR 603 
30 1 Y 1 A THR 603 ? A THR 604 
31 1 Y 1 A SER 604 ? A SER 605 
32 1 Y 1 A GLY 605 ? A GLY 606 
33 1 Y 1 A ALA 606 ? A ALA 607 
34 1 Y 1 A GLU 607 ? A GLU 608 
35 1 Y 1 A VAL 608 ? A VAL 609 
36 1 Y 1 A HIS 609 ? A HIS 610 
37 1 Y 1 A ALA 610 ? A ALA 611 
38 1 Y 1 A ALA 611 ? A ALA 612 
39 1 Y 1 B GLY 0   ? B GLY 1   
40 1 Y 1 B HIS 1   ? B HIS 2   
41 1 Y 1 B MET 2   ? B MET 3   
42 1 Y 1 B SER 3   ? B SER 4   
43 1 Y 1 B ILE 4   ? B ILE 5   
44 1 Y 1 B ASP 5   ? B ASP 6   
45 1 Y 1 B ILE 6   ? B ILE 7   
46 1 Y 1 B ARG 7   ? B ARG 8   
47 1 Y 1 B GLY 8   ? B GLY 9   
48 1 Y 1 B ALA 9   ? B ALA 10  
49 1 Y 1 B THR 10  ? B THR 11  
50 1 Y 1 B GLU 11  ? B GLU 12  
51 1 Y 1 B VAL 12  ? B VAL 13  
52 1 Y 1 B PRO 13  ? B PRO 14  
53 1 Y 1 B ALA 14  ? B ALA 15  
54 1 Y 1 B PRO 15  ? B PRO 16  
55 1 Y 1 B ASN 569 ? B ASN 570 
56 1 Y 1 B ARG 570 ? B ARG 571 
57 1 Y 1 B ASN 574 ? B ASN 575 
58 1 Y 1 B LEU 575 ? B LEU 576 
59 1 Y 1 B GLY 576 ? B GLY 577 
60 1 Y 1 B THR 601 ? B THR 602 
61 1 Y 1 B THR 602 ? B THR 603 
62 1 Y 1 B THR 603 ? B THR 604 
63 1 Y 1 B SER 604 ? B SER 605 
64 1 Y 1 B GLY 605 ? B GLY 606 
65 1 Y 1 B ALA 606 ? B ALA 607 
66 1 Y 1 B GLU 607 ? B GLU 608 
67 1 Y 1 B VAL 608 ? B VAL 609 
68 1 Y 1 B HIS 609 ? B HIS 610 
69 1 Y 1 B ALA 610 ? B ALA 611 
70 1 Y 1 B ALA 611 ? B ALA 612 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
MLI C1   C N N 247 
MLI C2   C N N 248 
MLI C3   C N N 249 
MLI O6   O N N 250 
MLI O7   O N N 251 
MLI O8   O N N 252 
MLI O9   O N N 253 
MLI H11  H N N 254 
MLI H12  H N N 255 
PHE N    N N N 256 
PHE CA   C N S 257 
PHE C    C N N 258 
PHE O    O N N 259 
PHE CB   C N N 260 
PHE CG   C Y N 261 
PHE CD1  C Y N 262 
PHE CD2  C Y N 263 
PHE CE1  C Y N 264 
PHE CE2  C Y N 265 
PHE CZ   C Y N 266 
PHE OXT  O N N 267 
PHE H    H N N 268 
PHE H2   H N N 269 
PHE HA   H N N 270 
PHE HB2  H N N 271 
PHE HB3  H N N 272 
PHE HD1  H N N 273 
PHE HD2  H N N 274 
PHE HE1  H N N 275 
PHE HE2  H N N 276 
PHE HZ   H N N 277 
PHE HXT  H N N 278 
PRO N    N N N 279 
PRO CA   C N S 280 
PRO C    C N N 281 
PRO O    O N N 282 
PRO CB   C N N 283 
PRO CG   C N N 284 
PRO CD   C N N 285 
PRO OXT  O N N 286 
PRO H    H N N 287 
PRO HA   H N N 288 
PRO HB2  H N N 289 
PRO HB3  H N N 290 
PRO HG2  H N N 291 
PRO HG3  H N N 292 
PRO HD2  H N N 293 
PRO HD3  H N N 294 
PRO HXT  H N N 295 
SER N    N N N 296 
SER CA   C N S 297 
SER C    C N N 298 
SER O    O N N 299 
SER CB   C N N 300 
SER OG   O N N 301 
SER OXT  O N N 302 
SER H    H N N 303 
SER H2   H N N 304 
SER HA   H N N 305 
SER HB2  H N N 306 
SER HB3  H N N 307 
SER HG   H N N 308 
SER HXT  H N N 309 
THR N    N N N 310 
THR CA   C N S 311 
THR C    C N N 312 
THR O    O N N 313 
THR CB   C N R 314 
THR OG1  O N N 315 
THR CG2  C N N 316 
THR OXT  O N N 317 
THR H    H N N 318 
THR H2   H N N 319 
THR HA   H N N 320 
THR HB   H N N 321 
THR HG1  H N N 322 
THR HG21 H N N 323 
THR HG22 H N N 324 
THR HG23 H N N 325 
THR HXT  H N N 326 
TRP N    N N N 327 
TRP CA   C N S 328 
TRP C    C N N 329 
TRP O    O N N 330 
TRP CB   C N N 331 
TRP CG   C Y N 332 
TRP CD1  C Y N 333 
TRP CD2  C Y N 334 
TRP NE1  N Y N 335 
TRP CE2  C Y N 336 
TRP CE3  C Y N 337 
TRP CZ2  C Y N 338 
TRP CZ3  C Y N 339 
TRP CH2  C Y N 340 
TRP OXT  O N N 341 
TRP H    H N N 342 
TRP H2   H N N 343 
TRP HA   H N N 344 
TRP HB2  H N N 345 
TRP HB3  H N N 346 
TRP HD1  H N N 347 
TRP HE1  H N N 348 
TRP HE3  H N N 349 
TRP HZ2  H N N 350 
TRP HZ3  H N N 351 
TRP HH2  H N N 352 
TRP HXT  H N N 353 
TYR N    N N N 354 
TYR CA   C N S 355 
TYR C    C N N 356 
TYR O    O N N 357 
TYR CB   C N N 358 
TYR CG   C Y N 359 
TYR CD1  C Y N 360 
TYR CD2  C Y N 361 
TYR CE1  C Y N 362 
TYR CE2  C Y N 363 
TYR CZ   C Y N 364 
TYR OH   O N N 365 
TYR OXT  O N N 366 
TYR H    H N N 367 
TYR H2   H N N 368 
TYR HA   H N N 369 
TYR HB2  H N N 370 
TYR HB3  H N N 371 
TYR HD1  H N N 372 
TYR HD2  H N N 373 
TYR HE1  H N N 374 
TYR HE2  H N N 375 
TYR HH   H N N 376 
TYR HXT  H N N 377 
VAL N    N N N 378 
VAL CA   C N S 379 
VAL C    C N N 380 
VAL O    O N N 381 
VAL CB   C N N 382 
VAL CG1  C N N 383 
VAL CG2  C N N 384 
VAL OXT  O N N 385 
VAL H    H N N 386 
VAL H2   H N N 387 
VAL HA   H N N 388 
VAL HB   H N N 389 
VAL HG11 H N N 390 
VAL HG12 H N N 391 
VAL HG13 H N N 392 
VAL HG21 H N N 393 
VAL HG22 H N N 394 
VAL HG23 H N N 395 
VAL HXT  H N N 396 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
MLI C1  C2   sing N N 235 
MLI C1  C3   sing N N 236 
MLI C1  H11  sing N N 237 
MLI C1  H12  sing N N 238 
MLI C2  O6   doub N N 239 
MLI C2  O7   sing N N 240 
MLI C3  O8   doub N N 241 
MLI C3  O9   sing N N 242 
PHE N   CA   sing N N 243 
PHE N   H    sing N N 244 
PHE N   H2   sing N N 245 
PHE CA  C    sing N N 246 
PHE CA  CB   sing N N 247 
PHE CA  HA   sing N N 248 
PHE C   O    doub N N 249 
PHE C   OXT  sing N N 250 
PHE CB  CG   sing N N 251 
PHE CB  HB2  sing N N 252 
PHE CB  HB3  sing N N 253 
PHE CG  CD1  doub Y N 254 
PHE CG  CD2  sing Y N 255 
PHE CD1 CE1  sing Y N 256 
PHE CD1 HD1  sing N N 257 
PHE CD2 CE2  doub Y N 258 
PHE CD2 HD2  sing N N 259 
PHE CE1 CZ   doub Y N 260 
PHE CE1 HE1  sing N N 261 
PHE CE2 CZ   sing Y N 262 
PHE CE2 HE2  sing N N 263 
PHE CZ  HZ   sing N N 264 
PHE OXT HXT  sing N N 265 
PRO N   CA   sing N N 266 
PRO N   CD   sing N N 267 
PRO N   H    sing N N 268 
PRO CA  C    sing N N 269 
PRO CA  CB   sing N N 270 
PRO CA  HA   sing N N 271 
PRO C   O    doub N N 272 
PRO C   OXT  sing N N 273 
PRO CB  CG   sing N N 274 
PRO CB  HB2  sing N N 275 
PRO CB  HB3  sing N N 276 
PRO CG  CD   sing N N 277 
PRO CG  HG2  sing N N 278 
PRO CG  HG3  sing N N 279 
PRO CD  HD2  sing N N 280 
PRO CD  HD3  sing N N 281 
PRO OXT HXT  sing N N 282 
SER N   CA   sing N N 283 
SER N   H    sing N N 284 
SER N   H2   sing N N 285 
SER CA  C    sing N N 286 
SER CA  CB   sing N N 287 
SER CA  HA   sing N N 288 
SER C   O    doub N N 289 
SER C   OXT  sing N N 290 
SER CB  OG   sing N N 291 
SER CB  HB2  sing N N 292 
SER CB  HB3  sing N N 293 
SER OG  HG   sing N N 294 
SER OXT HXT  sing N N 295 
THR N   CA   sing N N 296 
THR N   H    sing N N 297 
THR N   H2   sing N N 298 
THR CA  C    sing N N 299 
THR CA  CB   sing N N 300 
THR CA  HA   sing N N 301 
THR C   O    doub N N 302 
THR C   OXT  sing N N 303 
THR CB  OG1  sing N N 304 
THR CB  CG2  sing N N 305 
THR CB  HB   sing N N 306 
THR OG1 HG1  sing N N 307 
THR CG2 HG21 sing N N 308 
THR CG2 HG22 sing N N 309 
THR CG2 HG23 sing N N 310 
THR OXT HXT  sing N N 311 
TRP N   CA   sing N N 312 
TRP N   H    sing N N 313 
TRP N   H2   sing N N 314 
TRP CA  C    sing N N 315 
TRP CA  CB   sing N N 316 
TRP CA  HA   sing N N 317 
TRP C   O    doub N N 318 
TRP C   OXT  sing N N 319 
TRP CB  CG   sing N N 320 
TRP CB  HB2  sing N N 321 
TRP CB  HB3  sing N N 322 
TRP CG  CD1  doub Y N 323 
TRP CG  CD2  sing Y N 324 
TRP CD1 NE1  sing Y N 325 
TRP CD1 HD1  sing N N 326 
TRP CD2 CE2  doub Y N 327 
TRP CD2 CE3  sing Y N 328 
TRP NE1 CE2  sing Y N 329 
TRP NE1 HE1  sing N N 330 
TRP CE2 CZ2  sing Y N 331 
TRP CE3 CZ3  doub Y N 332 
TRP CE3 HE3  sing N N 333 
TRP CZ2 CH2  doub Y N 334 
TRP CZ2 HZ2  sing N N 335 
TRP CZ3 CH2  sing Y N 336 
TRP CZ3 HZ3  sing N N 337 
TRP CH2 HH2  sing N N 338 
TRP OXT HXT  sing N N 339 
TYR N   CA   sing N N 340 
TYR N   H    sing N N 341 
TYR N   H2   sing N N 342 
TYR CA  C    sing N N 343 
TYR CA  CB   sing N N 344 
TYR CA  HA   sing N N 345 
TYR C   O    doub N N 346 
TYR C   OXT  sing N N 347 
TYR CB  CG   sing N N 348 
TYR CB  HB2  sing N N 349 
TYR CB  HB3  sing N N 350 
TYR CG  CD1  doub Y N 351 
TYR CG  CD2  sing Y N 352 
TYR CD1 CE1  sing Y N 353 
TYR CD1 HD1  sing N N 354 
TYR CD2 CE2  doub Y N 355 
TYR CD2 HD2  sing N N 356 
TYR CE1 CZ   doub Y N 357 
TYR CE1 HE1  sing N N 358 
TYR CE2 CZ   sing Y N 359 
TYR CE2 HE2  sing N N 360 
TYR CZ  OH   sing N N 361 
TYR OH  HH   sing N N 362 
TYR OXT HXT  sing N N 363 
VAL N   CA   sing N N 364 
VAL N   H    sing N N 365 
VAL N   H2   sing N N 366 
VAL CA  C    sing N N 367 
VAL CA  CB   sing N N 368 
VAL CA  HA   sing N N 369 
VAL C   O    doub N N 370 
VAL C   OXT  sing N N 371 
VAL CB  CG1  sing N N 372 
VAL CB  CG2  sing N N 373 
VAL CB  HB   sing N N 374 
VAL CG1 HG11 sing N N 375 
VAL CG1 HG12 sing N N 376 
VAL CG1 HG13 sing N N 377 
VAL CG2 HG21 sing N N 378 
VAL CG2 HG22 sing N N 379 
VAL CG2 HG23 sing N N 380 
VAL OXT HXT  sing N N 381 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           GM-136235 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NOM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.011828 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008417 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.005945 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA A 1 17  ? -22.78147 -31.58817 -14.93624 1.000 74.62863  ? 16  ALA A N   1 
ATOM   2    C CA  . ALA A 1 17  ? -24.16849 -32.04439 -15.00064 1.000 80.99646  ? 16  ALA A CA  1 
ATOM   3    C C   . ALA A 1 17  ? -25.06503 -31.27150 -14.00951 1.000 78.53545  ? 16  ALA A C   1 
ATOM   4    O O   . ALA A 1 17  ? -24.68932 -31.09533 -12.84360 1.000 65.53659  ? 16  ALA A O   1 
ATOM   5    C CB  . ALA A 1 17  ? -24.23882 -33.55424 -14.73409 1.000 66.39232  ? 16  ALA A CB  1 
ATOM   6    N N   . CYS A 1 18  ? -26.24867 -30.77567 -14.51278 1.000 78.36268  ? 17  CYS A N   1 
ATOM   7    C CA  . CYS A 1 18  ? -27.32681 -30.11944 -13.72436 1.000 79.02098  ? 17  CYS A CA  1 
ATOM   8    C C   . CYS A 1 18  ? -28.66735 -30.52348 -14.35877 1.000 75.55409  ? 17  CYS A C   1 
ATOM   9    O O   . CYS A 1 18  ? -29.30751 -29.74178 -15.07706 1.000 76.63972  ? 17  CYS A O   1 
ATOM   10   C CB  . CYS A 1 18  ? -27.20346 -28.58243 -13.66052 1.000 75.33470  ? 17  CYS A CB  1 
ATOM   11   S SG  . CYS A 1 18  ? -25.58859 -27.80685 -13.30573 1.000 82.35012  ? 17  CYS A SG  1 
ATOM   12   N N   . SER A 1 19  ? -29.11439 -31.74556 -14.06333 1.000 65.36642  ? 18  SER A N   1 
ATOM   13   C CA  . SER A 1 19  ? -30.26343 -32.32361 -14.75667 1.000 66.91765  ? 18  SER A CA  1 
ATOM   14   C C   . SER A 1 19  ? -31.59796 -31.59830 -14.46670 1.000 63.50613  ? 18  SER A C   1 
ATOM   15   O O   . SER A 1 19  ? -32.61431 -31.94634 -15.09349 1.000 58.92980  ? 18  SER A O   1 
ATOM   16   C CB  . SER A 1 19  ? -30.34243 -33.81758 -14.39104 1.000 62.71389  ? 18  SER A CB  1 
ATOM   17   O OG  . SER A 1 19  ? -31.35435 -34.50518 -15.11284 1.000 64.85774  ? 18  SER A OG  1 
ATOM   18   N N   . TYR A 1 20  ? -31.61303 -30.56088 -13.60302 1.000 61.76442  ? 19  TYR A N   1 
ATOM   19   C CA  . TYR A 1 20  ? -32.83577 -30.13482 -12.92329 1.000 52.36616  ? 19  TYR A CA  1 
ATOM   20   C C   . TYR A 1 20  ? -33.14113 -28.63610 -13.00608 1.000 51.13358  ? 19  TYR A C   1 
ATOM   21   O O   . TYR A 1 20  ? -33.98531 -28.15480 -12.23906 1.000 43.44235  ? 19  TYR A O   1 
ATOM   22   C CB  . TYR A 1 20  ? -32.76728 -30.52657 -11.45253 1.000 47.78415  ? 19  TYR A CB  1 
ATOM   23   C CG  . TYR A 1 20  ? -32.43581 -31.95940 -11.18254 1.000 43.69612  ? 19  TYR A CG  1 
ATOM   24   C CD1 . TYR A 1 20  ? -31.12002 -32.38753 -11.10291 1.000 49.74399  ? 19  TYR A CD1 1 
ATOM   25   C CD2 . TYR A 1 20  ? -33.44319 -32.87768 -10.95593 1.000 39.98862  ? 19  TYR A CD2 1 
ATOM   26   C CE1 . TYR A 1 20  ? -30.82395 -33.70935 -10.82777 1.000 54.40256  ? 19  TYR A CE1 1 
ATOM   27   C CE2 . TYR A 1 20  ? -33.16346 -34.18912 -10.67773 1.000 45.16254  ? 19  TYR A CE2 1 
ATOM   28   C CZ  . TYR A 1 20  ? -31.85900 -34.60770 -10.61779 1.000 51.93710  ? 19  TYR A CZ  1 
ATOM   29   O OH  . TYR A 1 20  ? -31.59897 -35.92954 -10.33664 1.000 58.26362  ? 19  TYR A OH  1 
ATOM   30   N N   . ARG A 1 21  ? -32.49698 -27.88628 -13.91055 1.000 54.12544  ? 20  ARG A N   1 
ATOM   31   C CA  . ARG A 1 21  ? -32.70586 -26.43829 -13.96523 1.000 42.08872  ? 20  ARG A CA  1 
ATOM   32   C C   . ARG A 1 21  ? -34.18092 -26.07421 -14.13158 1.000 41.16302  ? 20  ARG A C   1 
ATOM   33   O O   . ARG A 1 21  ? -34.64894 -25.08434 -13.56058 1.000 41.07730  ? 20  ARG A O   1 
ATOM   34   C CB  . ARG A 1 21  ? -31.89201 -25.82221 -15.10125 1.000 39.41126  ? 20  ARG A CB  1 
ATOM   35   C CG  . ARG A 1 21  ? -30.39114 -26.02780 -15.00108 1.000 53.82785  ? 20  ARG A CG  1 
ATOM   36   C CD  . ARG A 1 21  ? -29.64357 -24.73491 -15.28772 1.000 49.16369  ? 20  ARG A CD  1 
ATOM   37   N NE  . ARG A 1 21  ? -30.40092 -23.89830 -16.20947 1.000 48.25111  ? 20  ARG A NE  1 
ATOM   38   C CZ  . ARG A 1 21  ? -30.31475 -22.57634 -16.25734 1.000 56.96950  ? 20  ARG A CZ  1 
ATOM   39   N NH1 . ARG A 1 21  ? -29.50742 -21.90714 -15.44270 1.000 57.50605  ? 20  ARG A NH1 1 
ATOM   40   N NH2 . ARG A 1 21  ? -31.05159 -21.90769 -17.14703 1.000 51.62670  ? 20  ARG A NH2 1 
ATOM   41   N N   . GLN A 1 22  ? -34.93290 -26.83982 -14.91925 1.000 41.03959  ? 21  GLN A N   1 
ATOM   42   C CA  . GLN A 1 22  ? -36.31617 -26.43673 -15.14379 1.000 39.00850  ? 21  GLN A CA  1 
ATOM   43   C C   . GLN A 1 22  ? -37.18652 -26.73954 -13.93803 1.000 42.25333  ? 21  GLN A C   1 
ATOM   44   O O   . GLN A 1 22  ? -38.10836 -25.97163 -13.64128 1.000 39.86912  ? 21  GLN A O   1 
ATOM   45   C CB  . GLN A 1 22  ? -36.88178 -27.10480 -16.39862 1.000 36.16773  ? 21  GLN A CB  1 
ATOM   46   C CG  . GLN A 1 22  ? -38.18646 -26.49296 -16.93000 1.000 36.00073  ? 21  GLN A CG  1 
ATOM   47   C CD  . GLN A 1 22  ? -38.12452 -24.96758 -17.10672 1.000 47.87366  ? 21  GLN A CD  1 
ATOM   48   O OE1 . GLN A 1 22  ? -37.04422 -24.37463 -17.32779 1.000 45.88222  ? 21  GLN A OE1 1 
ATOM   49   N NE2 . GLN A 1 22  ? -39.29287 -24.32546 -17.02238 1.000 41.27845  ? 21  GLN A NE2 1 
ATOM   50   N N   . VAL A 1 23  ? -36.89878 -27.83607 -13.23018 1.000 43.85706  ? 22  VAL A N   1 
ATOM   51   C CA  . VAL A 1 23  ? -37.58013 -28.11862 -11.96632 1.000 42.34817  ? 22  VAL A CA  1 
ATOM   52   C C   . VAL A 1 23  ? -37.53321 -26.90230 -11.04384 1.000 42.68859  ? 22  VAL A C   1 
ATOM   53   O O   . VAL A 1 23  ? -38.55929 -26.48216 -10.49354 1.000 44.03298  ? 22  VAL A O   1 
ATOM   54   C CB  . VAL A 1 23  ? -36.96570 -29.35854 -11.29409 1.000 43.48655  ? 22  VAL A CB  1 
ATOM   55   C CG1 . VAL A 1 23  ? -37.31203 -29.39727 -9.80420  1.000 43.02385  ? 22  VAL A CG1 1 
ATOM   56   C CG2 . VAL A 1 23  ? -37.44590 -30.61101 -11.98939 1.000 41.01098  ? 22  VAL A CG2 1 
ATOM   57   N N   . TYR A 1 24  ? -36.34168 -26.30799 -10.87507 1.000 38.52556  ? 23  TYR A N   1 
ATOM   58   C CA  . TYR A 1 24  ? -36.20081 -25.15818 -9.98340  1.000 34.16204  ? 23  TYR A CA  1 
ATOM   59   C C   . TYR A 1 24  ? -36.76586 -23.88455 -10.60765 1.000 36.37656  ? 23  TYR A C   1 
ATOM   60   O O   . TYR A 1 24  ? -37.40891 -23.07861 -9.92279  1.000 34.32224  ? 23  TYR A O   1 
ATOM   61   C CB  . TYR A 1 24  ? -34.73340 -25.00183 -9.58049  1.000 34.82682  ? 23  TYR A CB  1 
ATOM   62   C CG  . TYR A 1 24  ? -34.38664 -26.04781 -8.56379  1.000 37.41480  ? 23  TYR A CG  1 
ATOM   63   C CD1 . TYR A 1 24  ? -34.77453 -25.89713 -7.24857  1.000 35.27277  ? 23  TYR A CD1 1 
ATOM   64   C CD2 . TYR A 1 24  ? -33.75991 -27.22717 -8.92899  1.000 42.93506  ? 23  TYR A CD2 1 
ATOM   65   C CE1 . TYR A 1 24  ? -34.51659 -26.84818 -6.32150  1.000 35.10556  ? 23  TYR A CE1 1 
ATOM   66   C CE2 . TYR A 1 24  ? -33.49528 -28.20219 -7.99496  1.000 42.74266  ? 23  TYR A CE2 1 
ATOM   67   C CZ  . TYR A 1 24  ? -33.88023 -28.00126 -6.68628  1.000 41.95979  ? 23  TYR A CZ  1 
ATOM   68   O OH  . TYR A 1 24  ? -33.63681 -28.95383 -5.72020  1.000 47.41440  ? 23  TYR A OH  1 
ATOM   69   N N   . ASN A 1 25  ? -36.57044 -23.70340 -11.90988 1.000 39.45352  ? 24  ASN A N   1 
ATOM   70   C CA  . ASN A 1 25  ? -37.13432 -22.54332 -12.58994 1.000 41.27363  ? 24  ASN A CA  1 
ATOM   71   C C   . ASN A 1 25  ? -38.64973 -22.46164 -12.39352 1.000 38.83699  ? 24  ASN A C   1 
ATOM   72   O O   . ASN A 1 25  ? -39.19441 -21.37629 -12.15702 1.000 37.59845  ? 24  ASN A O   1 
ATOM   73   C CB  . ASN A 1 25  ? -36.76137 -22.60247 -14.07462 1.000 41.33834  ? 24  ASN A CB  1 
ATOM   74   C CG  . ASN A 1 25  ? -36.72249 -21.23511 -14.73947 1.000 39.57017  ? 24  ASN A CG  1 
ATOM   75   O OD1 . ASN A 1 25  ? -36.53281 -20.20296 -14.09610 1.000 36.99040  ? 24  ASN A OD1 1 
ATOM   76   N ND2 . ASN A 1 25  ? -36.92527 -21.22883 -16.05007 1.000 46.44043  ? 24  ASN A ND2 1 
ATOM   77   N N   . THR A 1 26  ? -39.34901 -23.59783 -12.47189 1.000 36.78995  ? 25  THR A N   1 
ATOM   78   C CA  . THR A 1 26  ? -40.79269 -23.57082 -12.25421 1.000 35.22609  ? 25  THR A CA  1 
ATOM   79   C C   . THR A 1 26  ? -41.11705 -23.29081 -10.79045 1.000 39.32951  ? 25  THR A C   1 
ATOM   80   O O   . THR A 1 26  ? -42.01484 -22.48887 -10.49302 1.000 35.18390  ? 25  THR A O   1 
ATOM   81   C CB  . THR A 1 26  ? -41.43668 -24.88886 -12.70026 1.000 35.97889  ? 25  THR A CB  1 
ATOM   82   O OG1 . THR A 1 26  ? -40.96782 -25.24773 -14.00174 1.000 48.39643  ? 25  THR A OG1 1 
ATOM   83   C CG2 . THR A 1 26  ? -42.94155 -24.75118 -12.76980 1.000 34.62074  ? 25  THR A CG2 1 
ATOM   84   N N   . ARG A 1 27  ? -40.40766 -23.95911 -9.86455  1.000 37.57961  ? 26  ARG A N   1 
ATOM   85   C CA  . ARG A 1 27  ? -40.53619 -23.65209 -8.43980  1.000 38.35182  ? 26  ARG A CA  1 
ATOM   86   C C   . ARG A 1 27  ? -40.40052 -22.16507 -8.17751  1.000 39.16960  ? 26  ARG A C   1 
ATOM   87   O O   . ARG A 1 27  ? -41.21054 -21.56023 -7.46284  1.000 37.81205  ? 26  ARG A O   1 
ATOM   88   C CB  . ARG A 1 27  ? -39.46594 -24.37003 -7.63322  1.000 34.89293  ? 26  ARG A CB  1 
ATOM   89   C CG  . ARG A 1 27  ? -39.89048 -25.56994 -6.91733  1.000 30.28283  ? 26  ARG A CG  1 
ATOM   90   C CD  . ARG A 1 27  ? -38.68715 -26.12111 -6.25212  1.000 29.23284  ? 26  ARG A CD  1 
ATOM   91   N NE  . ARG A 1 27  ? -38.62074 -27.55102 -6.48632  1.000 37.04375  ? 26  ARG A NE  1 
ATOM   92   C CZ  . ARG A 1 27  ? -37.97356 -28.38913 -5.70312  1.000 38.66607  ? 26  ARG A CZ  1 
ATOM   93   N NH1 . ARG A 1 27  ? -37.34074 -27.96269 -4.61944  1.000 38.87150  ? 26  ARG A NH1 1 
ATOM   94   N NH2 . ARG A 1 27  ? -37.96703 -29.68209 -6.01004  1.000 38.05375  ? 26  ARG A NH2 1 
ATOM   95   N N   . LEU A 1 28  ? -39.33771 -21.57626 -8.71034  1.000 33.63999  ? 27  LEU A N   1 
ATOM   96   C CA  . LEU A 1 28  ? -39.10577 -20.16710 -8.49119  1.000 35.49180  ? 27  LEU A CA  1 
ATOM   97   C C   . LEU A 1 28  ? -40.27543 -19.34159 -9.00563  1.000 37.64306  ? 27  LEU A C   1 
ATOM   98   O O   . LEU A 1 28  ? -40.84216 -18.52805 -8.27188  1.000 37.68528  ? 27  LEU A O   1 
ATOM   99   C CB  . LEU A 1 28  ? -37.79646 -19.77133 -9.15708  1.000 40.85429  ? 27  LEU A CB  1 
ATOM   100  C CG  . LEU A 1 28  ? -36.77472 -19.46068 -8.07491  1.000 40.22532  ? 27  LEU A CG  1 
ATOM   101  C CD1 . LEU A 1 28  ? -35.63525 -18.70320 -8.68087  1.000 42.64898  ? 27  LEU A CD1 1 
ATOM   102  C CD2 . LEU A 1 28  ? -37.44537 -18.63248 -6.98920  1.000 37.09953  ? 27  LEU A CD2 1 
ATOM   103  N N   . ALA A 1 29  ? -40.67456 -19.55992 -10.25719 1.000 38.14927  ? 28  ALA A N   1 
ATOM   104  C CA  . ALA A 1 29  ? -41.79299 -18.80058 -10.79246 1.000 37.93832  ? 28  ALA A CA  1 
ATOM   105  C C   . ALA A 1 29  ? -43.03142 -18.98016 -9.92277  1.000 37.26450  ? 28  ALA A C   1 
ATOM   106  O O   . ALA A 1 29  ? -43.77804 -18.01888 -9.68728  1.000 38.33684  ? 28  ALA A O   1 
ATOM   107  C CB  . ALA A 1 29  ? -42.05890 -19.20847 -12.24064 1.000 33.43164  ? 28  ALA A CB  1 
ATOM   108  N N   . ARG A 1 30  ? -43.24134 -20.19048 -9.39737  1.000 31.42903  ? 29  ARG A N   1 
ATOM   109  C CA  . ARG A 1 30  ? -44.39636 -20.41976 -8.53338  1.000 37.40523  ? 29  ARG A CA  1 
ATOM   110  C C   . ARG A 1 30  ? -44.29546 -19.60443 -7.24627  1.000 41.61480  ? 29  ARG A C   1 
ATOM   111  O O   . ARG A 1 30  ? -45.28578 -19.00304 -6.80253  1.000 41.42074  ? 29  ARG A O   1 
ATOM   112  C CB  . ARG A 1 30  ? -44.54466 -21.91045 -8.21886  1.000 39.81837  ? 29  ARG A CB  1 
ATOM   113  C CG  . ARG A 1 30  ? -45.95448 -22.32178 -7.81847  1.000 42.91154  ? 29  ARG A CG  1 
ATOM   114  C CD  . ARG A 1 30  ? -46.10787 -23.83511 -7.59685  1.000 47.62325  ? 29  ARG A CD  1 
ATOM   115  N NE  . ARG A 1 30  ? -45.45508 -24.28532 -6.36891  1.000 58.06416  ? 29  ARG A NE  1 
ATOM   116  C CZ  . ARG A 1 30  ? -46.04817 -24.96948 -5.39504  1.000 55.96954  ? 29  ARG A CZ  1 
ATOM   117  N NH1 . ARG A 1 30  ? -47.33853 -25.26273 -5.43564  1.000 57.88094  ? 29  ARG A NH1 1 
ATOM   118  N NH2 . ARG A 1 30  ? -45.33458 -25.34640 -4.33958  1.000 53.24983  ? 29  ARG A NH2 1 
ATOM   119  N N   . LYS A 1 31  ? -43.10363 -19.55323 -6.64089  1.000 37.37415  ? 30  LYS A N   1 
ATOM   120  C CA  . LYS A 1 31  ? -42.92893 -18.73885 -5.44339  1.000 34.34997  ? 30  LYS A CA  1 
ATOM   121  C C   . LYS A 1 31  ? -43.18531 -17.26326 -5.74646  1.000 36.42823  ? 30  LYS A C   1 
ATOM   122  O O   . LYS A 1 31  ? -43.90963 -16.58739 -5.00334  1.000 38.66640  ? 30  LYS A O   1 
ATOM   123  C CB  . LYS A 1 31  ? -41.53507 -18.94965 -4.84901  1.000 27.97391  ? 30  LYS A CB  1 
ATOM   124  C CG  . LYS A 1 31  ? -41.24687 -18.04127 -3.67369  1.000 34.06546  ? 30  LYS A CG  1 
ATOM   125  C CD  . LYS A 1 31  ? -39.79035 -18.12650 -3.23190  1.000 34.29107  ? 30  LYS A CD  1 
ATOM   126  C CE  . LYS A 1 31  ? -39.53580 -17.26949 -1.98939  1.000 32.95431  ? 30  LYS A CE  1 
ATOM   127  N NZ  . LYS A 1 31  ? -38.38179 -17.82206 -1.25009  1.000 34.71998  ? 30  LYS A NZ  1 
ATOM   128  N N   . ILE A 1 32  ? -42.61749 -16.74722 -6.84566  1.000 32.56318  ? 31  ILE A N   1 
ATOM   129  C CA  . ILE A 1 32  ? -42.89466 -15.36190 -7.23030  1.000 35.09367  ? 31  ILE A CA  1 
ATOM   130  C C   . ILE A 1 32  ? -44.39310 -15.14229 -7.35467  1.000 35.55923  ? 31  ILE A C   1 
ATOM   131  O O   . ILE A 1 32  ? -44.93612 -14.15192 -6.85339  1.000 37.59079  ? 31  ILE A O   1 
ATOM   132  C CB  . ILE A 1 32  ? -42.18308 -14.97379 -8.54043  1.000 34.42312  ? 31  ILE A CB  1 
ATOM   133  C CG1 . ILE A 1 32  ? -40.68553 -15.23792 -8.48045  1.000 36.23449  ? 31  ILE A CG1 1 
ATOM   134  C CG2 . ILE A 1 32  ? -42.38812 -13.50534 -8.79540  1.000 31.68669  ? 31  ILE A CG2 1 
ATOM   135  C CD1 . ILE A 1 32  ? -39.99243 -15.02467 -9.79862  1.000 33.62052  ? 31  ILE A CD1 1 
ATOM   136  N N   . LEU A 1 33  ? -45.08697 -16.05658 -8.02869  1.000 32.44160  ? 32  LEU A N   1 
ATOM   137  C CA  . LEU A 1 33  ? -46.50816 -15.83072 -8.22518  1.000 34.69105  ? 32  LEU A CA  1 
ATOM   138  C C   . LEU A 1 33  ? -47.22407 -15.76261 -6.89393  1.000 39.70531  ? 32  LEU A C   1 
ATOM   139  O O   . LEU A 1 33  ? -48.01556 -14.84384 -6.66386  1.000 41.38734  ? 32  LEU A O   1 
ATOM   140  C CB  . LEU A 1 33  ? -47.11509 -16.90407 -9.11919  1.000 34.35817  ? 32  LEU A CB  1 
ATOM   141  C CG  . LEU A 1 33  ? -47.13062 -16.40581 -10.56425 1.000 36.47671  ? 32  LEU A CG  1 
ATOM   142  C CD1 . LEU A 1 33  ? -47.92324 -17.33735 -11.43235 1.000 37.25356  ? 32  LEU A CD1 1 
ATOM   143  C CD2 . LEU A 1 33  ? -47.71238 -15.01542 -10.63197 1.000 29.22077  ? 32  LEU A CD2 1 
ATOM   144  N N   . ALA A 1 34  ? -46.90111 -16.67682 -5.97276  1.000 36.97472  ? 33  ALA A N   1 
ATOM   145  C CA  . ALA A 1 34  ? -47.68567 -16.77530 -4.74700  1.000 35.89466  ? 33  ALA A CA  1 
ATOM   146  C C   . ALA A 1 34  ? -47.28992 -15.71658 -3.71221  1.000 42.99517  ? 33  ALA A C   1 
ATOM   147  O O   . ALA A 1 34  ? -48.15406 -15.21104 -2.98202  1.000 42.87684  ? 33  ALA A O   1 
ATOM   148  C CB  . ALA A 1 34  ? -47.55585 -18.17553 -4.16493  1.000 32.41989  ? 33  ALA A CB  1 
ATOM   149  N N   . GLU A 1 35  ? -45.99684 -15.37619 -3.61746  1.000 40.69643  ? 34  GLU A N   1 
ATOM   150  C CA  . GLU A 1 35  ? -45.58363 -14.30531 -2.71245  1.000 37.55255  ? 34  GLU A CA  1 
ATOM   151  C C   . GLU A 1 35  ? -46.12574 -12.95634 -3.17275  1.000 40.82702  ? 34  GLU A C   1 
ATOM   152  O O   . GLU A 1 35  ? -46.58617 -12.15177 -2.35277  1.000 36.19792  ? 34  GLU A O   1 
ATOM   153  C CB  . GLU A 1 35  ? -44.06124 -14.24388 -2.61974  1.000 34.85811  ? 34  GLU A CB  1 
ATOM   154  C CG  . GLU A 1 35  ? -43.41852 -15.13094 -1.56190  1.000 45.86798  ? 34  GLU A CG  1 
ATOM   155  C CD  . GLU A 1 35  ? -44.28188 -15.34946 -0.31987  1.000 48.48539  ? 34  GLU A CD  1 
ATOM   156  O OE1 . GLU A 1 35  ? -44.39107 -14.43722 0.55079   1.000 47.90060  ? 34  GLU A OE1 1 
ATOM   157  O OE2 . GLU A 1 35  ? -44.83329 -16.46672 -0.22144  1.000 42.15904  ? 34  GLU A OE2 1 
ATOM   158  N N   . PHE A 1 36  ? -46.05829 -12.68527 -4.48209  1.000 36.65876  ? 35  PHE A N   1 
ATOM   159  C CA  . PHE A 1 36  ? -46.51725 -11.40326 -4.99355  1.000 38.17460  ? 35  PHE A CA  1 
ATOM   160  C C   . PHE A 1 36  ? -48.03252 -11.33347 -5.02216  1.000 43.67009  ? 35  PHE A C   1 
ATOM   161  O O   . PHE A 1 36  ? -48.60616 -10.23694 -4.97201  1.000 43.92631  ? 35  PHE A O   1 
ATOM   162  C CB  . PHE A 1 36  ? -45.96677 -11.15507 -6.39122  1.000 40.58379  ? 35  PHE A CB  1 
ATOM   163  C CG  . PHE A 1 36  ? -44.51486 -10.80363 -6.41609  1.000 46.15414  ? 35  PHE A CG  1 
ATOM   164  C CD1 . PHE A 1 36  ? -43.78255 -10.73067 -5.23527  1.000 44.05810  ? 35  PHE A CD1 1 
ATOM   165  C CD2 . PHE A 1 36  ? -43.87036 -10.54705 -7.62684  1.000 41.14068  ? 35  PHE A CD2 1 
ATOM   166  C CE1 . PHE A 1 36  ? -42.42688 -10.41125 -5.25973  1.000 45.39154  ? 35  PHE A CE1 1 
ATOM   167  C CE2 . PHE A 1 36  ? -42.52662 -10.22996 -7.65709  1.000 38.26441  ? 35  PHE A CE2 1 
ATOM   168  C CZ  . PHE A 1 36  ? -41.80313 -10.15964 -6.47246  1.000 41.88783  ? 35  PHE A CZ  1 
ATOM   169  N N   . CYS A 1 37  ? -48.69738 -12.48103 -5.12873  1.000 40.04560  ? 36  CYS A N   1 
ATOM   170  C CA  . CYS A 1 37  ? -50.13710 -12.49618 -4.91888  1.000 42.04639  ? 36  CYS A CA  1 
ATOM   171  C C   . CYS A 1 37  ? -50.46627 -12.19800 -3.46793  1.000 41.92454  ? 36  CYS A C   1 
ATOM   172  O O   . CYS A 1 37  ? -51.32875 -11.35727 -3.17650  1.000 39.57535  ? 36  CYS A O   1 
ATOM   173  C CB  . CYS A 1 37  ? -50.71681 -13.84222 -5.33270  1.000 41.37086  ? 36  CYS A CB  1 
ATOM   174  S SG  . CYS A 1 37  ? -50.88734 -13.93851 -7.09435  1.000 45.81783  ? 36  CYS A SG  1 
ATOM   175  N N   . HIS A 1 38  ? -49.75830 -12.86664 -2.54834  1.000 40.17120  ? 37  HIS A N   1 
ATOM   176  C CA  . HIS A 1 38  ? -50.00643 -12.70192 -1.12177  1.000 37.38885  ? 37  HIS A CA  1 
ATOM   177  C C   . HIS A 1 38  ? -49.84745 -11.25227 -0.70217  1.000 38.79016  ? 37  HIS A C   1 
ATOM   178  O O   . HIS A 1 38  ? -50.70112 -10.70870 0.00570   1.000 44.98113  ? 37  HIS A O   1 
ATOM   179  C CB  . HIS A 1 38  ? -49.06598 -13.60456 -0.34072  1.000 39.27699  ? 37  HIS A CB  1 
ATOM   180  C CG  . HIS A 1 38  ? -49.09231 -13.39773 1.13976   1.000 37.67345  ? 37  HIS A CG  1 
ATOM   181  N ND1 . HIS A 1 38  ? -50.10003 -13.88352 1.94342   1.000 39.17309  ? 37  HIS A ND1 1 
ATOM   182  C CD2 . HIS A 1 38  ? -48.20352 -12.80168 1.96827   1.000 39.38311  ? 37  HIS A CD2 1 
ATOM   183  C CE1 . HIS A 1 38  ? -49.84024 -13.57542 3.20233   1.000 44.63581  ? 37  HIS A CE1 1 
ATOM   184  N NE2 . HIS A 1 38  ? -48.69777 -12.91418 3.24427   1.000 39.28003  ? 37  HIS A NE2 1 
ATOM   185  N N   . GLU A 1 39  ? -48.79072 -10.59442 -1.15896  1.000 38.64210  ? 38  GLU A N   1 
ATOM   186  C CA  . GLU A 1 39  ? -48.61861 -9.18499  -0.83404  1.000 43.47153  ? 38  GLU A CA  1 
ATOM   187  C C   . GLU A 1 39  ? -49.47931 -8.26049  -1.67982  1.000 46.85592  ? 38  GLU A C   1 
ATOM   188  O O   . GLU A 1 39  ? -49.39936 -7.03952  -1.48613  1.000 45.45405  ? 38  GLU A O   1 
ATOM   189  C CB  . GLU A 1 39  ? -47.16136 -8.76960  -0.98738  1.000 43.23720  ? 38  GLU A CB  1 
ATOM   190  C CG  . GLU A 1 39  ? -46.20177 -9.63513  -0.23821  1.000 47.86535  ? 38  GLU A CG  1 
ATOM   191  C CD  . GLU A 1 39  ? -44.82654 -9.04781  -0.24576  1.000 48.74319  ? 38  GLU A CD  1 
ATOM   192  O OE1 . GLU A 1 39  ? -44.72489 -7.82878  -0.48761  1.000 44.38828  ? 38  GLU A OE1 1 
ATOM   193  O OE2 . GLU A 1 39  ? -43.86060 -9.80642  -0.02805  1.000 49.11262  ? 38  GLU A OE2 1 
ATOM   194  N N   . ARG A 1 40  ? -50.29350 -8.80440  -2.59438  1.000 45.70561  ? 39  ARG A N   1 
ATOM   195  C CA  . ARG A 1 40  ? -51.11658 -8.01152  -3.51595  1.000 47.74974  ? 39  ARG A CA  1 
ATOM   196  C C   . ARG A 1 40  ? -50.27904 -7.06261  -4.36373  1.000 46.15067  ? 39  ARG A C   1 
ATOM   197  O O   . ARG A 1 40  ? -50.70088 -5.93667  -4.63833  1.000 46.46669  ? 39  ARG A O   1 
ATOM   198  C CB  . ARG A 1 40  ? -52.19606 -7.21366  -2.78167  1.000 40.60505  ? 39  ARG A CB  1 
ATOM   199  C CG  . ARG A 1 40  ? -52.83153 -7.93222  -1.65427  1.000 41.14398  ? 39  ARG A CG  1 
ATOM   200  C CD  . ARG A 1 40  ? -54.17703 -7.35194  -1.38763  1.000 51.43652  ? 39  ARG A CD  1 
ATOM   201  N NE  . ARG A 1 40  ? -55.03660 -8.28254  -0.66983  1.000 62.63707  ? 39  ARG A NE  1 
ATOM   202  C CZ  . ARG A 1 40  ? -55.84445 -7.92456  0.31987   1.000 69.51236  ? 39  ARG A CZ  1 
ATOM   203  N NH1 . ARG A 1 40  ? -55.89755 -6.66887  0.75052   1.000 61.72956  ? 39  ARG A NH1 1 
ATOM   204  N NH2 . ARG A 1 40  ? -56.61294 -8.84767  0.89633   1.000 72.35261  ? 39  ARG A NH2 1 
ATOM   205  N N   . LEU A 1 41  ? -49.06242 -7.48241  -4.72666  1.000 48.00347  ? 40  LEU A N   1 
ATOM   206  C CA  . LEU A 1 41  ? -48.34703 -6.86040  -5.83726  1.000 47.02675  ? 40  LEU A CA  1 
ATOM   207  C C   . LEU A 1 41  ? -48.86456 -7.37029  -7.16850  1.000 48.38341  ? 40  LEU A C   1 
ATOM   208  O O   . LEU A 1 41  ? -48.64310 -6.73340  -8.19678  1.000 52.77025  ? 40  LEU A O   1 
ATOM   209  C CB  . LEU A 1 41  ? -46.85195 -7.14753  -5.74881  1.000 42.69730  ? 40  LEU A CB  1 
ATOM   210  C CG  . LEU A 1 41  ? -46.13646 -6.57756  -4.53609  1.000 44.88149  ? 40  LEU A CG  1 
ATOM   211  C CD1 . LEU A 1 41  ? -44.89227 -7.41460  -4.20105  1.000 44.82502  ? 40  LEU A CD1 1 
ATOM   212  C CD2 . LEU A 1 41  ? -45.77110 -5.15729  -4.83722  1.000 45.88560  ? 40  LEU A CD2 1 
ATOM   213  N N   . VAL A 1 42  ? -49.55636 -8.50544  -7.15003  1.000 48.79830  ? 41  VAL A N   1 
ATOM   214  C CA  . VAL A 1 42  ? -50.13242 -9.14933  -8.31783  1.000 41.92027  ? 41  VAL A CA  1 
ATOM   215  C C   . VAL A 1 42  ? -51.53307 -9.57686  -7.90754  1.000 43.16931  ? 41  VAL A C   1 
ATOM   216  O O   . VAL A 1 42  ? -51.69081 -10.43131 -7.03174  1.000 51.98764  ? 41  VAL A O   1 
ATOM   217  C CB  . VAL A 1 42  ? -49.30731 -10.36012 -8.77791  1.000 45.61012  ? 41  VAL A CB  1 
ATOM   218  C CG1 . VAL A 1 42  ? -50.05706 -11.19099 -9.83493  1.000 38.23541  ? 41  VAL A CG1 1 
ATOM   219  C CG2 . VAL A 1 42  ? -47.96677 -9.89775  -9.28285  1.000 40.56540  ? 41  VAL A CG2 1 
ATOM   220  N N   . ARG A 1 43  ? -52.54303 -8.97446  -8.51085  1.000 44.34893  ? 42  ARG A N   1 
ATOM   221  C CA  . ARG A 1 43  ? -53.92733 -9.35884  -8.27412  1.000 40.85763  ? 42  ARG A CA  1 
ATOM   222  C C   . ARG A 1 43  ? -54.46796 -10.05816 -9.51082  1.000 44.96829  ? 42  ARG A C   1 
ATOM   223  O O   . ARG A 1 43  ? -54.80166 -9.39542  -10.50579 1.000 48.59461  ? 42  ARG A O   1 
ATOM   224  C CB  . ARG A 1 43  ? -54.75713 -8.12747  -7.91633  1.000 38.97531  ? 42  ARG A CB  1 
ATOM   225  C CG  . ARG A 1 43  ? -53.92641 -7.15630  -7.10139  1.000 48.88543  ? 42  ARG A CG  1 
ATOM   226  C CD  . ARG A 1 43  ? -54.57648 -5.81368  -6.91223  1.000 53.08135  ? 42  ARG A CD  1 
ATOM   227  N NE  . ARG A 1 43  ? -54.98393 -5.62612  -5.52407  1.000 62.37112  ? 42  ARG A NE  1 
ATOM   228  C CZ  . ARG A 1 43  ? -54.40456 -4.77856  -4.67819  1.000 68.81805  ? 42  ARG A CZ  1 
ATOM   229  N NH1 . ARG A 1 43  ? -53.34744 -4.05410  -5.03307  1.000 64.78249  ? 42  ARG A NH1 1 
ATOM   230  N NH2 . ARG A 1 43  ? -54.88788 -4.66382  -3.44013  1.000 64.67974  ? 42  ARG A NH2 1 
ATOM   231  N N   . PRO A 1 44  ? -54.53064 -11.38418 -9.51835  1.000 42.97645  ? 43  PRO A N   1 
ATOM   232  C CA  . PRO A 1 44  ? -54.90153 -12.12615 -10.72965 1.000 44.51853  ? 43  PRO A CA  1 
ATOM   233  C C   . PRO A 1 44  ? -56.40338 -12.05506 -10.96076 1.000 43.22042  ? 43  PRO A C   1 
ATOM   234  O O   . PRO A 1 44  ? -57.15392 -11.50735 -10.16164 1.000 50.10467  ? 43  PRO A O   1 
ATOM   235  C CB  . PRO A 1 44  ? -54.45716 -13.56167 -10.43217 1.000 43.52673  ? 43  PRO A CB  1 
ATOM   236  C CG  . PRO A 1 44  ? -53.80466 -13.52245 -9.06796  1.000 41.05046  ? 43  PRO A CG  1 
ATOM   237  C CD  . PRO A 1 44  ? -54.21375 -12.26784 -8.39082  1.000 35.96552  ? 43  PRO A CD  1 
ATOM   238  N N   . THR A 1 45  ? -56.83718 -12.65654 -12.05800 1.000 34.74600  ? 44  THR A N   1 
ATOM   239  C CA  . THR A 1 45  ? -58.22634 -12.59067 -12.48114 1.000 38.33855  ? 44  THR A CA  1 
ATOM   240  C C   . THR A 1 45  ? -58.83088 -13.98204 -12.42072 1.000 40.13456  ? 44  THR A C   1 
ATOM   241  O O   . THR A 1 45  ? -58.23659 -14.94235 -12.92186 1.000 40.28593  ? 44  THR A O   1 
ATOM   242  C CB  . THR A 1 45  ? -58.33778 -12.01456 -13.90441 1.000 47.03063  ? 44  THR A CB  1 
ATOM   243  O OG1 . THR A 1 45  ? -57.91763 -10.64424 -13.91159 1.000 51.56207  ? 44  THR A OG1 1 
ATOM   244  C CG2 . THR A 1 45  ? -59.75487 -12.10358 -14.42308 1.000 43.32015  ? 44  THR A CG2 1 
ATOM   245  N N   . GLU A 1 46  ? -60.00943 -14.09135 -11.81952 1.000 38.35377  ? 45  GLU A N   1 
ATOM   246  C CA  . GLU A 1 46  ? -60.67304 -15.37845 -11.69445 1.000 38.74007  ? 45  GLU A CA  1 
ATOM   247  C C   . GLU A 1 46  ? -61.52105 -15.63142 -12.93115 1.000 44.49777  ? 45  GLU A C   1 
ATOM   248  O O   . GLU A 1 46  ? -62.45523 -14.87841 -13.20085 1.000 48.96322  ? 45  GLU A O   1 
ATOM   249  C CB  . GLU A 1 46  ? -61.52902 -15.42445 -10.43684 1.000 36.17939  ? 45  GLU A CB  1 
ATOM   250  C CG  . GLU A 1 46  ? -61.36060 -16.72472 -9.70480  1.000 49.82549  ? 45  GLU A CG  1 
ATOM   251  C CD  . GLU A 1 46  ? -62.30412 -16.90240 -8.54030  1.000 57.92580  ? 45  GLU A CD  1 
ATOM   252  O OE1 . GLU A 1 46  ? -63.19269 -16.01967 -8.36109  1.000 55.96999  ? 45  GLU A OE1 1 
ATOM   253  O OE2 . GLU A 1 46  ? -62.15339 -17.94978 -7.83843  1.000 50.13991  ? 45  GLU A OE2 1 
ATOM   254  N N   . LEU A 1 47  ? -61.19697 -16.68635 -13.68142 1.000 45.71739  ? 46  LEU A N   1 
ATOM   255  C CA  . LEU A 1 47  ? -61.90772 -16.99517 -14.92278 1.000 43.74511  ? 46  LEU A CA  1 
ATOM   256  C C   . LEU A 1 47  ? -63.05399 -17.97098 -14.67113 1.000 49.33174  ? 46  LEU A C   1 
ATOM   257  O O   . LEU A 1 47  ? -64.19711 -17.70152 -15.04722 1.000 58.72060  ? 46  LEU A O   1 
ATOM   258  C CB  . LEU A 1 47  ? -60.93392 -17.54714 -15.97523 1.000 43.38908  ? 46  LEU A CB  1 
ATOM   259  C CG  . LEU A 1 47  ? -59.80925 -16.62790 -16.48734 1.000 43.67836  ? 46  LEU A CG  1 
ATOM   260  C CD1 . LEU A 1 47  ? -58.81246 -17.39597 -17.30081 1.000 42.77990  ? 46  LEU A CD1 1 
ATOM   261  C CD2 . LEU A 1 47  ? -60.32461 -15.45427 -17.30057 1.000 36.12228  ? 46  LEU A CD2 1 
ATOM   262  N N   . SER A 1 48  ? -62.74964 -19.11875 -14.08511 1.000 53.29391  ? 47  SER A N   1 
ATOM   263  C CA  . SER A 1 48  ? -63.66864 -19.98836 -13.36931 1.000 48.57411  ? 47  SER A CA  1 
ATOM   264  C C   . SER A 1 48  ? -63.32147 -19.91176 -11.90581 1.000 56.37727  ? 47  SER A C   1 
ATOM   265  O O   . SER A 1 48  ? -62.27057 -19.37760 -11.53683 1.000 57.42169  ? 47  SER A O   1 
ATOM   266  C CB  . SER A 1 48  ? -63.54224 -21.44386 -13.83510 1.000 48.46670  ? 47  SER A CB  1 
ATOM   267  O OG  . SER A 1 48  ? -63.96325 -21.59760 -15.17527 1.000 66.75647  ? 47  SER A OG  1 
ATOM   268  N N   . PRO A 1 49  ? -64.17470 -20.43949 -11.02741 1.000 59.19286  ? 48  PRO A N   1 
ATOM   269  C CA  . PRO A 1 49  ? -63.75653 -20.63400 -9.63359  1.000 42.91866  ? 48  PRO A CA  1 
ATOM   270  C C   . PRO A 1 49  ? -62.45117 -21.40833 -9.53117  1.000 42.65040  ? 48  PRO A C   1 
ATOM   271  O O   . PRO A 1 49  ? -62.35178 -22.55148 -9.98531  1.000 34.19943  ? 48  PRO A O   1 
ATOM   272  C CB  . PRO A 1 49  ? -64.92526 -21.41855 -9.03662  1.000 42.26229  ? 48  PRO A CB  1 
ATOM   273  C CG  . PRO A 1 49  ? -66.10070 -20.90941 -9.78052  1.000 44.42137  ? 48  PRO A CG  1 
ATOM   274  C CD  . PRO A 1 49  ? -65.61970 -20.67289 -11.20099 1.000 53.84365  ? 48  PRO A CD  1 
ATOM   275  N N   . GLY A 1 50  ? -61.43331 -20.77226 -8.95208  1.000 46.53719  ? 49  GLY A N   1 
ATOM   276  C CA  . GLY A 1 50  ? -60.17462 -21.42269 -8.66472  1.000 39.68035  ? 49  GLY A CA  1 
ATOM   277  C C   . GLY A 1 50  ? -59.18321 -21.41321 -9.79444  1.000 38.69180  ? 49  GLY A C   1 
ATOM   278  O O   . GLY A 1 50  ? -58.04753 -21.86881 -9.60606  1.000 36.08028  ? 49  GLY A O   1 
ATOM   279  N N   . ARG A 1 51  ? -59.57959 -20.91791 -10.96416 1.000 48.83134  ? 50  ARG A N   1 
ATOM   280  C CA  . ARG A 1 51  ? -58.75096 -20.90567 -12.16098 1.000 41.81674  ? 50  ARG A CA  1 
ATOM   281  C C   . ARG A 1 51  ? -58.48336 -19.45224 -12.52071 1.000 43.00781  ? 50  ARG A C   1 
ATOM   282  O O   . ARG A 1 51  ? -59.42848 -18.66664 -12.67035 1.000 42.31152  ? 50  ARG A O   1 
ATOM   283  C CB  . ARG A 1 51  ? -59.44661 -21.64905 -13.30525 1.000 38.81829  ? 50  ARG A CB  1 
ATOM   284  C CG  . ARG A 1 51  ? -60.20672 -22.89910 -12.85612 1.000 47.03969  ? 50  ARG A CG  1 
ATOM   285  C CD  . ARG A 1 51  ? -60.19994 -24.01571 -13.89312 1.000 41.54851  ? 50  ARG A CD  1 
ATOM   286  N NE  . ARG A 1 51  ? -59.03207 -24.88191 -13.79179 1.000 42.98958  ? 50  ARG A NE  1 
ATOM   287  C CZ  . ARG A 1 51  ? -59.01765 -26.06766 -13.19316 1.000 49.48190  ? 50  ARG A CZ  1 
ATOM   288  N NH1 . ARG A 1 51  ? -60.11340 -26.59138 -12.64979 1.000 43.71515  ? 50  ARG A NH1 1 
ATOM   289  N NH2 . ARG A 1 51  ? -57.87714 -26.75269 -13.14708 1.000 48.00790  ? 50  ARG A NH2 1 
ATOM   290  N N   . TYR A 1 52  ? -57.19822 -19.09825 -12.65150 1.000 38.49926  ? 51  TYR A N   1 
ATOM   291  C CA  . TYR A 1 52  ? -56.76426 -17.70821 -12.68780 1.000 37.85044  ? 51  TYR A CA  1 
ATOM   292  C C   . TYR A 1 52  ? -55.91126 -17.40980 -13.91415 1.000 38.55104  ? 51  TYR A C   1 
ATOM   293  O O   . TYR A 1 52  ? -55.23660 -18.28549 -14.46625 1.000 42.78880  ? 51  TYR A O   1 
ATOM   294  C CB  . TYR A 1 52  ? -55.96555 -17.35705 -11.42180 1.000 38.66174  ? 51  TYR A CB  1 
ATOM   295  C CG  . TYR A 1 52  ? -56.74891 -17.53936 -10.13002 1.000 39.48263  ? 51  TYR A CG  1 
ATOM   296  C CD1 . TYR A 1 52  ? -56.74357 -18.74672 -9.43873  1.000 37.15414  ? 51  TYR A CD1 1 
ATOM   297  C CD2 . TYR A 1 52  ? -57.48659 -16.49907 -9.60586  1.000 39.32289  ? 51  TYR A CD2 1 
ATOM   298  C CE1 . TYR A 1 52  ? -57.45396 -18.89885 -8.27830  1.000 36.49404  ? 51  TYR A CE1 1 
ATOM   299  C CE2 . TYR A 1 52  ? -58.18818 -16.64455 -8.44372  1.000 40.14800  ? 51  TYR A CE2 1 
ATOM   300  C CZ  . TYR A 1 52  ? -58.17753 -17.83592 -7.78753  1.000 39.83094  ? 51  TYR A CZ  1 
ATOM   301  O OH  . TYR A 1 52  ? -58.91121 -17.93750 -6.63121  1.000 49.26888  ? 51  TYR A OH  1 
ATOM   302  N N   . VAL A 1 53  ? -55.93470 -16.15110 -14.32280 1.000 36.59443  ? 52  VAL A N   1 
ATOM   303  C CA  . VAL A 1 53  ? -55.03240 -15.63462 -15.34037 1.000 38.19788  ? 52  VAL A CA  1 
ATOM   304  C C   . VAL A 1 53  ? -54.34522 -14.39684 -14.77674 1.000 41.72420  ? 52  VAL A C   1 
ATOM   305  O O   . VAL A 1 53  ? -54.97253 -13.57728 -14.09583 1.000 43.00857  ? 52  VAL A O   1 
ATOM   306  C CB  . VAL A 1 53  ? -55.77326 -15.30537 -16.65643 1.000 40.17578  ? 52  VAL A CB  1 
ATOM   307  C CG1 . VAL A 1 53  ? -56.76957 -14.19073 -16.44623 1.000 35.09710  ? 52  VAL A CG1 1 
ATOM   308  C CG2 . VAL A 1 53  ? -54.79117 -14.91604 -17.73900 1.000 43.00407  ? 52  VAL A CG2 1 
ATOM   309  N N   . VAL A 1 54  ? -53.04563 -14.28546 -15.02420 1.000 39.82653  ? 53  VAL A N   1 
ATOM   310  C CA  . VAL A 1 54  ? -52.27775 -13.07996 -14.74467 1.000 37.07288  ? 53  VAL A CA  1 
ATOM   311  C C   . VAL A 1 54  ? -51.72860 -12.57099 -16.06970 1.000 48.18649  ? 53  VAL A C   1 
ATOM   312  O O   . VAL A 1 54  ? -51.01523 -13.30167 -16.77421 1.000 48.90243  ? 53  VAL A O   1 
ATOM   313  C CB  . VAL A 1 54  ? -51.14737 -13.34836 -13.74617 1.000 36.97784  ? 53  VAL A CB  1 
ATOM   314  C CG1 . VAL A 1 54  ? -50.00824 -12.39201 -13.96913 1.000 33.23245  ? 53  VAL A CG1 1 
ATOM   315  C CG2 . VAL A 1 54  ? -51.66925 -13.21379 -12.33443 1.000 38.86375  ? 53  VAL A CG2 1 
ATOM   316  N N   . HIS A 1 55  ? -52.05988 -11.32294 -16.40882 1.000 49.55760  ? 54  HIS A N   1 
ATOM   317  C CA  . HIS A 1 55  ? -51.65388 -10.71880 -17.67517 1.000 49.07850  ? 54  HIS A CA  1 
ATOM   318  C C   . HIS A 1 55  ? -50.32463 -9.98695  -17.53330 1.000 50.98817  ? 54  HIS A C   1 
ATOM   319  O O   . HIS A 1 55  ? -50.13388 -9.19909  -16.60043 1.000 57.45501  ? 54  HIS A O   1 
ATOM   320  C CB  . HIS A 1 55  ? -52.73302 -9.75810  -18.18411 1.000 48.63712  ? 54  HIS A CB  1 
ATOM   321  C CG  . HIS A 1 55  ? -54.02624 -10.43821 -18.50397 1.000 50.57589  ? 54  HIS A CG  1 
ATOM   322  N ND1 . HIS A 1 55  ? -54.19880 -11.20955 -19.63603 1.000 51.20403  ? 54  HIS A ND1 1 
ATOM   323  C CD2 . HIS A 1 55  ? -55.20188 -10.48328 -17.83277 1.000 47.96137  ? 54  HIS A CD2 1 
ATOM   324  C CE1 . HIS A 1 55  ? -55.42549 -11.70081 -19.64719 1.000 49.81629  ? 54  HIS A CE1 1 
ATOM   325  N NE2 . HIS A 1 55  ? -56.05497 -11.27445 -18.56541 1.000 53.49095  ? 54  HIS A NE2 1 
ATOM   326  N N   . SER A 1 56  ? -49.41366 -10.23988 -18.46743 1.000 49.70631  ? 55  SER A N   1 
ATOM   327  C CA  . SER A 1 56  ? -48.16900 -9.49866  -18.49115 1.000 48.46248  ? 55  SER A CA  1 
ATOM   328  C C   . SER A 1 56  ? -48.44251 -8.01555  -18.72237 1.000 54.45347  ? 55  SER A C   1 
ATOM   329  O O   . SER A 1 56  ? -49.54990 -7.59733  -19.08222 1.000 55.73766  ? 55  SER A O   1 
ATOM   330  C CB  . SER A 1 56  ? -47.24257 -10.04433 -19.56965 1.000 52.18316  ? 55  SER A CB  1 
ATOM   331  O OG  . SER A 1 56  ? -47.30182 -9.23563  -20.72651 1.000 60.40531  ? 55  SER A OG  1 
ATOM   332  N N   . ASP A 1 57  ? -47.40359 -7.20981  -18.51434 1.000 54.42056  ? 56  ASP A N   1 
ATOM   333  C CA  . ASP A 1 57  ? -47.57539 -5.77000  -18.65638 1.000 57.11354  ? 56  ASP A CA  1 
ATOM   334  C C   . ASP A 1 57  ? -47.72924 -5.35357  -20.11631 1.000 55.27883  ? 56  ASP A C   1 
ATOM   335  O O   . ASP A 1 57  ? -48.46702 -4.41185  -20.41752 1.000 52.58891  ? 56  ASP A O   1 
ATOM   336  C CB  . ASP A 1 57  ? -46.40796 -5.04896  -17.99844 1.000 52.12700  ? 56  ASP A CB  1 
ATOM   337  C CG  . ASP A 1 57  ? -46.49019 -5.09291  -16.48998 1.000 57.52263  ? 56  ASP A CG  1 
ATOM   338  O OD1 . ASP A 1 57  ? -47.33994 -5.86328  -15.97088 1.000 56.17281  ? 56  ASP A OD1 1 
ATOM   339  O OD2 . ASP A 1 57  ? -45.71855 -4.35038  -15.83528 1.000 54.79832  ? 56  ASP A OD2 1 
ATOM   340  N N   . ASP A 1 58  ? -47.05414 -6.03368  -21.02912 1.000 56.46193  ? 57  ASP A N   1 
ATOM   341  C CA  . ASP A 1 58  ? -47.19617 -5.75808  -22.44867 1.000 48.26315  ? 57  ASP A CA  1 
ATOM   342  C C   . ASP A 1 58  ? -48.37822 -6.47555  -23.06087 1.000 53.67400  ? 57  ASP A C   1 
ATOM   343  O O   . ASP A 1 58  ? -48.51495 -6.46580  -24.28672 1.000 64.28551  ? 57  ASP A O   1 
ATOM   344  C CB  . ASP A 1 58  ? -45.90470 -6.13684  -23.19398 1.000 49.45329  ? 57  ASP A CB  1 
ATOM   345  C CG  . ASP A 1 58  ? -45.43491 -7.57171  -22.90204 1.000 62.81476  ? 57  ASP A CG  1 
ATOM   346  O OD1 . ASP A 1 58  ? -46.26330 -8.51215  -22.84241 1.000 59.97731  ? 57  ASP A OD1 1 
ATOM   347  O OD2 . ASP A 1 58  ? -44.21523 -7.75823  -22.70138 1.000 73.59552  ? 57  ASP A OD2 1 
ATOM   348  N N   . ARG A 1 59  ? -49.20696 -7.12979  -22.25360 1.000 53.15906  ? 58  ARG A N   1 
ATOM   349  C CA  . ARG A 1 59  ? -50.37442 -7.88067  -22.71136 1.000 54.53953  ? 58  ARG A CA  1 
ATOM   350  C C   . ARG A 1 59  ? -50.05557 -8.92463  -23.77065 1.000 50.42571  ? 58  ARG A C   1 
ATOM   351  O O   . ARG A 1 59  ? -50.96986 -9.41484  -24.43620 1.000 48.99594  ? 58  ARG A O   1 
ATOM   352  C CB  . ARG A 1 59  ? -51.45438 -6.94239  -23.23200 1.000 46.78247  ? 58  ARG A CB  1 
ATOM   353  C CG  . ARG A 1 59  ? -51.96396 -6.02689  -22.15161 1.000 54.99022  ? 58  ARG A CG  1 
ATOM   354  C CD  . ARG A 1 59  ? -52.18121 -6.81286  -20.88367 1.000 60.19195  ? 58  ARG A CD  1 
ATOM   355  N NE  . ARG A 1 59  ? -53.52957 -6.66865  -20.34848 1.000 62.77725  ? 58  ARG A NE  1 
ATOM   356  C CZ  . ARG A 1 59  ? -53.80715 -6.14404  -19.16285 1.000 63.10152  ? 58  ARG A CZ  1 
ATOM   357  N NH1 . ARG A 1 59  ? -52.84812 -5.67074  -18.37412 1.000 54.66440  ? 58  ARG A NH1 1 
ATOM   358  N NH2 . ARG A 1 59  ? -55.07311 -6.11602  -18.74932 1.000 62.32900  ? 58  ARG A NH2 1 
ATOM   359  N N   . GLU A 1 60  ? -48.78595 -9.27578  -23.94636 1.000 49.36928  ? 59  GLU A N   1 
ATOM   360  C CA  . GLU A 1 60  ? -48.41046 -10.33911 -24.86175 1.000 52.43202  ? 59  GLU A CA  1 
ATOM   361  C C   . GLU A 1 60  ? -48.43445 -11.70226 -24.19830 1.000 53.76011  ? 59  GLU A C   1 
ATOM   362  O O   . GLU A 1 60  ? -48.84453 -12.68675 -24.82110 1.000 51.82803  ? 59  GLU A O   1 
ATOM   363  C CB  . GLU A 1 60  ? -47.01688 -10.09324 -25.43477 1.000 61.07551  ? 59  GLU A CB  1 
ATOM   364  C CG  . GLU A 1 60  ? -46.75976 -8.69269  -25.96522 1.000 67.06895  ? 59  GLU A CG  1 
ATOM   365  C CD  . GLU A 1 60  ? -46.85982 -8.62451  -27.48612 1.000 82.64726  ? 59  GLU A CD  1 
ATOM   366  O OE1 . GLU A 1 60  ? -45.97354 -8.00311  -28.11895 1.000 90.48514  ? 59  GLU A OE1 1 
ATOM   367  O OE2 . GLU A 1 60  ? -47.83451 -9.17097  -28.05085 1.000 86.87000  ? 59  GLU A OE2 1 
ATOM   368  N N   . THR A 1 61  ? -47.97695 -11.78265 -22.95618 1.000 56.72956  ? 60  THR A N   1 
ATOM   369  C CA  . THR A 1 61  ? -47.93653 -13.03477 -22.22334 1.000 50.91493  ? 60  THR A CA  1 
ATOM   370  C C   . THR A 1 61  ? -49.15096 -13.14121 -21.31474 1.000 50.79424  ? 60  THR A C   1 
ATOM   371  O O   . THR A 1 61  ? -49.66342 -12.13831 -20.81038 1.000 47.90432  ? 60  THR A O   1 
ATOM   372  C CB  . THR A 1 61  ? -46.66555 -13.14044 -21.38921 1.000 53.41919  ? 60  THR A CB  1 
ATOM   373  O OG1 . THR A 1 61  ? -45.54487 -12.67622 -22.15681 1.000 54.32130  ? 60  THR A OG1 1 
ATOM   374  C CG2 . THR A 1 61  ? -46.44222 -14.58766 -20.94141 1.000 52.23067  ? 60  THR A CG2 1 
ATOM   375  N N   . GLU A 1 62  ? -49.62647 -14.37127 -21.14603 1.000 50.25508  ? 61  GLU A N   1 
ATOM   376  C CA  . GLU A 1 62  ? -50.68424 -14.70246 -20.20710 1.000 47.77394  ? 61  GLU A CA  1 
ATOM   377  C C   . GLU A 1 62  ? -50.18395 -15.84515 -19.34567 1.000 48.26512  ? 61  GLU A C   1 
ATOM   378  O O   . GLU A 1 62  ? -49.43413 -16.70606 -19.81620 1.000 50.32428  ? 61  GLU A O   1 
ATOM   379  C CB  . GLU A 1 62  ? -51.99056 -15.09464 -20.91285 1.000 43.90947  ? 61  GLU A CB  1 
ATOM   380  C CG  . GLU A 1 62  ? -53.00351 -13.95344 -21.02590 1.000 47.63401  ? 61  GLU A CG  1 
ATOM   381  C CD  . GLU A 1 62  ? -54.31999 -14.36157 -21.70758 1.000 55.35627  ? 61  GLU A CD  1 
ATOM   382  O OE1 . GLU A 1 62  ? -54.76206 -15.52350 -21.55725 1.000 50.89113  ? 61  GLU A OE1 1 
ATOM   383  O OE2 . GLU A 1 62  ? -54.91881 -13.50701 -22.40079 1.000 61.05092  ? 61  GLU A OE2 1 
ATOM   384  N N   . TYR A 1 63  ? -50.57496 -15.83644 -18.08006 1.000 43.28594  ? 62  TYR A N   1 
ATOM   385  C CA  . TYR A 1 63  ? -50.12003 -16.83126 -17.11847 1.000 42.73006  ? 62  TYR A CA  1 
ATOM   386  C C   . TYR A 1 63  ? -51.36250 -17.46757 -16.51122 1.000 42.99278  ? 62  TYR A C   1 
ATOM   387  O O   . TYR A 1 63  ? -52.10325 -16.81323 -15.76655 1.000 43.06158  ? 62  TYR A O   1 
ATOM   388  C CB  . TYR A 1 63  ? -49.21818 -16.19006 -16.05508 1.000 40.57678  ? 62  TYR A CB  1 
ATOM   389  C CG  . TYR A 1 63  ? -47.82524 -15.83561 -16.54766 1.000 40.44238  ? 62  TYR A CG  1 
ATOM   390  C CD1 . TYR A 1 63  ? -46.86922 -16.81885 -16.75477 1.000 37.28117  ? 62  TYR A CD1 1 
ATOM   391  C CD2 . TYR A 1 63  ? -47.47110 -14.51098 -16.81450 1.000 46.26492  ? 62  TYR A CD2 1 
ATOM   392  C CE1 . TYR A 1 63  ? -45.60516 -16.49376 -17.21879 1.000 44.35297  ? 62  TYR A CE1 1 
ATOM   393  C CE2 . TYR A 1 63  ? -46.20269 -14.17470 -17.28499 1.000 39.76550  ? 62  TYR A CE2 1 
ATOM   394  C CZ  . TYR A 1 63  ? -45.27988 -15.17016 -17.47979 1.000 45.09677  ? 62  TYR A CZ  1 
ATOM   395  O OH  . TYR A 1 63  ? -44.02564 -14.85087 -17.92548 1.000 43.08755  ? 62  TYR A OH  1 
ATOM   396  N N   . ARG A 1 64  ? -51.61281 -18.72785 -16.84067 1.000 37.16767  ? 63  ARG A N   1 
ATOM   397  C CA  . ARG A 1 64  ? -52.82269 -19.39035 -16.38502 1.000 38.84694  ? 63  ARG A CA  1 
ATOM   398  C C   . ARG A 1 64  ? -52.49120 -20.48853 -15.39021 1.000 38.51677  ? 63  ARG A C   1 
ATOM   399  O O   . ARG A 1 64  ? -51.56369 -21.27844 -15.59884 1.000 38.98232  ? 63  ARG A O   1 
ATOM   400  C CB  . ARG A 1 64  ? -53.61607 -19.94212 -17.57137 1.000 43.77979  ? 63  ARG A CB  1 
ATOM   401  C CG  . ARG A 1 64  ? -53.83942 -18.87408 -18.64579 1.000 45.73345  ? 63  ARG A CG  1 
ATOM   402  C CD  . ARG A 1 64  ? -55.07097 -19.10122 -19.52053 1.000 51.47806  ? 63  ARG A CD  1 
ATOM   403  N NE  . ARG A 1 64  ? -55.52504 -17.83237 -20.08901 1.000 66.79575  ? 63  ARG A NE  1 
ATOM   404  C CZ  . ARG A 1 64  ? -56.77118 -17.55482 -20.46233 1.000 69.34216  ? 63  ARG A CZ  1 
ATOM   405  N NH1 . ARG A 1 64  ? -57.73162 -18.47027 -20.40718 1.000 67.32655  ? 63  ARG A NH1 1 
ATOM   406  N NH2 . ARG A 1 64  ? -57.05923 -16.32672 -20.90644 1.000 50.32678  ? 63  ARG A NH2 1 
ATOM   407  N N   . PHE A 1 65  ? -53.25476 -20.54126 -14.30811 1.000 31.11336  ? 64  PHE A N   1 
ATOM   408  C CA  . PHE A 1 65  ? -53.01251 -21.58272 -13.32513 1.000 33.17175  ? 64  PHE A CA  1 
ATOM   409  C C   . PHE A 1 65  ? -54.26632 -21.78826 -12.49585 1.000 34.61359  ? 64  PHE A C   1 
ATOM   410  O O   . PHE A 1 65  ? -55.07558 -20.87157 -12.31845 1.000 33.45541  ? 64  PHE A O   1 
ATOM   411  C CB  . PHE A 1 65  ? -51.83662 -21.21079 -12.41236 1.000 37.58901  ? 64  PHE A CB  1 
ATOM   412  C CG  . PHE A 1 65  ? -51.98307 -19.85235 -11.78697 1.000 39.85897  ? 64  PHE A CG  1 
ATOM   413  C CD1 . PHE A 1 65  ? -52.70024 -19.68916 -10.60348 1.000 36.18903  ? 64  PHE A CD1 1 
ATOM   414  C CD2 . PHE A 1 65  ? -51.45338 -18.72762 -12.40723 1.000 40.15042  ? 64  PHE A CD2 1 
ATOM   415  C CE1 . PHE A 1 65  ? -52.87465 -18.44466 -10.04107 1.000 31.89559  ? 64  PHE A CE1 1 
ATOM   416  C CE2 . PHE A 1 65  ? -51.61939 -17.47724 -11.83723 1.000 40.98719  ? 64  PHE A CE2 1 
ATOM   417  C CZ  . PHE A 1 65  ? -52.33974 -17.34395 -10.64847 1.000 39.58837  ? 64  PHE A CZ  1 
ATOM   418  N N   . ARG A 1 66  ? -54.40578 -22.99055 -11.96777 1.000 36.66420  ? 65  ARG A N   1 
ATOM   419  C CA  . ARG A 1 66  ? -55.36822 -23.22950 -10.90360 1.000 40.06180  ? 65  ARG A CA  1 
ATOM   420  C C   . ARG A 1 66  ? -54.68682 -22.97885 -9.55770  1.000 40.40943  ? 65  ARG A C   1 
ATOM   421  O O   . ARG A 1 66  ? -53.48703 -23.23242 -9.39739  1.000 41.75476  ? 65  ARG A O   1 
ATOM   422  C CB  . ARG A 1 66  ? -55.91685 -24.65491 -10.99994 1.000 33.50824  ? 65  ARG A CB  1 
ATOM   423  C CG  . ARG A 1 66  ? -56.66932 -25.10727 -9.80167  1.000 37.24903  ? 65  ARG A CG  1 
ATOM   424  C CD  . ARG A 1 66  ? -57.08361 -26.56643 -9.91996  1.000 42.22636  ? 65  ARG A CD  1 
ATOM   425  N NE  . ARG A 1 66  ? -56.03938 -27.49319 -9.48600  1.000 44.12602  ? 65  ARG A NE  1 
ATOM   426  C CZ  . ARG A 1 66  ? -55.71638 -27.74653 -8.22441  1.000 40.48909  ? 65  ARG A CZ  1 
ATOM   427  N NH1 . ARG A 1 66  ? -56.32407 -27.14076 -7.21631  1.000 38.97179  ? 65  ARG A NH1 1 
ATOM   428  N NH2 . ARG A 1 66  ? -54.74986 -28.62325 -7.96978  1.000 43.33064  ? 65  ARG A NH2 1 
ATOM   429  N N   . ALA A 1 67  ? -55.43595 -22.43995 -8.60026  1.000 34.75174  ? 66  ALA A N   1 
ATOM   430  C CA  . ALA A 1 67  ? -54.86144 -22.26277 -7.28107  1.000 32.21024  ? 66  ALA A CA  1 
ATOM   431  C C   . ALA A 1 67  ? -55.94300 -22.37215 -6.21841  1.000 35.45167  ? 66  ALA A C   1 
ATOM   432  O O   . ALA A 1 67  ? -57.10928 -22.04987 -6.45854  1.000 34.84688  ? 66  ALA A O   1 
ATOM   433  C CB  . ALA A 1 67  ? -54.12930 -20.92916 -7.17178  1.000 34.14050  ? 66  ALA A CB  1 
ATOM   434  N N   . GLU A 1 68  ? -55.53207 -22.85890 -5.04534  1.000 38.42426  ? 67  GLU A N   1 
ATOM   435  C CA  . GLU A 1 68  ? -56.33883 -22.89440 -3.82922  1.000 35.80905  ? 67  GLU A CA  1 
ATOM   436  C C   . GLU A 1 68  ? -55.80166 -21.83765 -2.87997  1.000 36.45758  ? 67  GLU A C   1 
ATOM   437  O O   . GLU A 1 68  ? -54.58586 -21.73272 -2.69901  1.000 41.02341  ? 67  GLU A O   1 
ATOM   438  C CB  . GLU A 1 68  ? -56.27421 -24.26671 -3.16062  1.000 32.87338  ? 67  GLU A CB  1 
ATOM   439  C CG  . GLU A 1 68  ? -57.17930 -25.31483 -3.79037  1.000 45.86507  ? 67  GLU A CG  1 
ATOM   440  C CD  . GLU A 1 68  ? -56.73173 -26.76085 -3.51086  1.000 58.18641  ? 67  GLU A CD  1 
ATOM   441  O OE1 . GLU A 1 68  ? -56.49210 -27.09872 -2.31828  1.000 56.84957  ? 67  GLU A OE1 1 
ATOM   442  O OE2 . GLU A 1 68  ? -56.64247 -27.56208 -4.48564  1.000 51.95907  ? 67  GLU A OE2 1 
ATOM   443  N N   . ILE A 1 69  ? -56.68813 -21.04574 -2.29127  1.000 35.87679  ? 68  ILE A N   1 
ATOM   444  C CA  . ILE A 1 69  ? -56.28216 -20.00246 -1.35441  1.000 36.09371  ? 68  ILE A CA  1 
ATOM   445  C C   . ILE A 1 69  ? -56.43523 -20.59715 0.03677   1.000 35.40329  ? 68  ILE A C   1 
ATOM   446  O O   . ILE A 1 69  ? -57.56005 -20.82950 0.49483   1.000 34.90463  ? 68  ILE A O   1 
ATOM   447  C CB  . ILE A 1 69  ? -57.11322 -18.71417 -1.48784  1.000 38.28607  ? 68  ILE A CB  1 
ATOM   448  C CG1 . ILE A 1 69  ? -56.70676 -17.81785 -2.68020  1.000 33.03937  ? 68  ILE A CG1 1 
ATOM   449  C CG2 . ILE A 1 69  ? -56.92428 -17.86842 -0.24173  1.000 35.16373  ? 68  ILE A CG2 1 
ATOM   450  C CD1 . ILE A 1 69  ? -56.52362 -18.48700 -3.97192  1.000 38.71664  ? 68  ILE A CD1 1 
ATOM   451  N N   . LEU A 1 70  ? -55.31135 -20.85721 0.70455   1.000 35.53930  ? 69  LEU A N   1 
ATOM   452  C CA  . LEU A 1 70  ? -55.30415 -21.42722 2.04493   1.000 33.19902  ? 69  LEU A CA  1 
ATOM   453  C C   . LEU A 1 70  ? -55.32033 -20.29842 3.07687   1.000 36.10443  ? 69  LEU A C   1 
ATOM   454  O O   . LEU A 1 70  ? -55.51507 -19.12458 2.75242   1.000 43.09197  ? 69  LEU A O   1 
ATOM   455  C CB  . LEU A 1 70  ? -54.09955 -22.34431 2.22093   1.000 30.82477  ? 69  LEU A CB  1 
ATOM   456  C CG  . LEU A 1 70  ? -53.89972 -23.34928 1.08904   1.000 30.10270  ? 69  LEU A CG  1 
ATOM   457  C CD1 . LEU A 1 70  ? -52.64581 -24.14194 1.28762   1.000 29.62038  ? 69  LEU A CD1 1 
ATOM   458  C CD2 . LEU A 1 70  ? -55.07831 -24.26850 1.00343   1.000 34.61077  ? 69  LEU A CD2 1 
ATOM   459  N N   . SER A 1 71  ? -55.11862 -20.63018 4.34004   1.000 34.07338  ? 70  SER A N   1 
ATOM   460  C CA  . SER A 1 71  ? -55.25669 -19.60516 5.35413   1.000 31.58771  ? 70  SER A CA  1 
ATOM   461  C C   . SER A 1 71  ? -54.09527 -18.62474 5.27595   1.000 35.14276  ? 70  SER A C   1 
ATOM   462  O O   . SER A 1 71  ? -53.01429 -18.94702 4.78347   1.000 37.52183  ? 70  SER A O   1 
ATOM   463  C CB  . SER A 1 71  ? -55.32428 -20.24852 6.72363   1.000 35.81007  ? 70  SER A CB  1 
ATOM   464  O OG  . SER A 1 71  ? -56.40988 -21.14857 6.76049   1.000 33.15199  ? 70  SER A OG  1 
ATOM   465  N N   . LEU A 1 72  ? -54.33649 -17.41247 5.77022   1.000 36.52726  ? 71  LEU A N   1 
ATOM   466  C CA  . LEU A 1 72  ? -53.36349 -16.31649 5.71108   1.000 37.60173  ? 71  LEU A CA  1 
ATOM   467  C C   . LEU A 1 72  ? -53.03097 -15.93464 4.26864   1.000 42.73289  ? 71  LEU A C   1 
ATOM   468  O O   . LEU A 1 72  ? -51.87054 -15.67004 3.92308   1.000 43.27539  ? 71  LEU A O   1 
ATOM   469  C CB  . LEU A 1 72  ? -52.09287 -16.64962 6.48534   1.000 31.81224  ? 71  LEU A CB  1 
ATOM   470  C CG  . LEU A 1 72  ? -52.28454 -16.55215 7.98311   1.000 35.41967  ? 71  LEU A CG  1 
ATOM   471  C CD1 . LEU A 1 72  ? -51.01415 -16.96895 8.68277   1.000 37.24491  ? 71  LEU A CD1 1 
ATOM   472  C CD2 . LEU A 1 72  ? -52.67516 -15.13579 8.33658   1.000 38.13693  ? 71  LEU A CD2 1 
ATOM   473  N N   . ASP A 1 73  ? -54.06371 -15.89515 3.42091   1.000 41.73382  ? 72  ASP A N   1 
ATOM   474  C CA  . ASP A 1 73  ? -53.92331 -15.43778 2.03665   1.000 40.34663  ? 72  ASP A CA  1 
ATOM   475  C C   . ASP A 1 73  ? -52.79554 -16.18384 1.33164   1.000 39.63879  ? 72  ASP A C   1 
ATOM   476  O O   . ASP A 1 73  ? -51.98825 -15.59730 0.61074   1.000 40.21154  ? 72  ASP A O   1 
ATOM   477  C CB  . ASP A 1 73  ? -53.70850 -13.92258 1.98228   1.000 38.66339  ? 72  ASP A CB  1 
ATOM   478  C CG  . ASP A 1 73  ? -55.01114 -13.13954 2.15968   1.000 44.82806  ? 72  ASP A CG  1 
ATOM   479  O OD1 . ASP A 1 73  ? -56.08767 -13.76934 2.07212   1.000 44.75785  ? 72  ASP A OD1 1 
ATOM   480  O OD2 . ASP A 1 73  ? -54.96631 -11.90913 2.40390   1.000 50.29553  ? 72  ASP A OD2 1 
ATOM   481  N N   . SER A 1 74  ? -52.73622 -17.49576 1.56321   1.000 39.30771  ? 73  SER A N   1 
ATOM   482  C CA  . SER A 1 74  ? -51.70711 -18.34685 0.98925   1.000 36.75460  ? 73  SER A CA  1 
ATOM   483  C C   . SER A 1 74  ? -52.20621 -18.88188 -0.34945  1.000 39.78315  ? 73  SER A C   1 
ATOM   484  O O   . SER A 1 74  ? -53.21169 -19.60032 -0.40584  1.000 35.87369  ? 73  SER A O   1 
ATOM   485  C CB  . SER A 1 74  ? -51.35380 -19.48146 1.94753   1.000 35.47791  ? 73  SER A CB  1 
ATOM   486  O OG  . SER A 1 74  ? -49.99099 -19.87306 1.80375   1.000 43.21538  ? 73  SER A OG  1 
ATOM   487  N N   . TRP A 1 75  ? -51.52307 -18.50412 -1.42586  1.000 37.41321  ? 74  TRP A N   1 
ATOM   488  C CA  . TRP A 1 75  ? -51.86700 -18.96821 -2.75858  1.000 31.18052  ? 74  TRP A CA  1 
ATOM   489  C C   . TRP A 1 75  ? -51.12435 -20.26725 -3.02189  1.000 36.88107  ? 74  TRP A C   1 
ATOM   490  O O   . TRP A 1 75  ? -49.91361 -20.25549 -3.25884  1.000 37.86376  ? 74  TRP A O   1 
ATOM   491  C CB  . TRP A 1 75  ? -51.49488 -17.92365 -3.79877  1.000 39.45546  ? 74  TRP A CB  1 
ATOM   492  C CG  . TRP A 1 75  ? -52.51310 -16.82774 -3.97490  1.000 43.65416  ? 74  TRP A CG  1 
ATOM   493  C CD1 . TRP A 1 75  ? -52.74630 -15.79001 -3.13062  1.000 42.76570  ? 74  TRP A CD1 1 
ATOM   494  C CD2 . TRP A 1 75  ? -53.40153 -16.64965 -5.08393  1.000 35.96009  ? 74  TRP A CD2 1 
ATOM   495  N NE1 . TRP A 1 75  ? -53.72687 -14.97995 -3.63956  1.000 37.92010  ? 74  TRP A NE1 1 
ATOM   496  C CE2 . TRP A 1 75  ? -54.14760 -15.48880 -4.83659  1.000 31.97247  ? 74  TRP A CE2 1 
ATOM   497  C CE3 . TRP A 1 75  ? -53.63773 -17.36435 -6.25956  1.000 39.27779  ? 74  TRP A CE3 1 
ATOM   498  C CZ2 . TRP A 1 75  ? -55.12285 -15.02632 -5.71191  1.000 32.97537  ? 74  TRP A CZ2 1 
ATOM   499  C CZ3 . TRP A 1 75  ? -54.61050 -16.89912 -7.13750  1.000 42.01413  ? 74  TRP A CZ3 1 
ATOM   500  C CH2 . TRP A 1 75  ? -55.34132 -15.74447 -6.85529  1.000 37.76871  ? 74  TRP A CH2 1 
ATOM   501  N N   . CYS A 1 76  ? -51.84481 -21.38598 -2.99578  1.000 36.08711  ? 75  CYS A N   1 
ATOM   502  C CA  . CYS A 1 76  ? -51.26735 -22.69677 -3.27491  1.000 34.62028  ? 75  CYS A CA  1 
ATOM   503  C C   . CYS A 1 76  ? -51.53157 -23.03440 -4.73969  1.000 39.31178  ? 75  CYS A C   1 
ATOM   504  O O   . CYS A 1 76  ? -52.62522 -23.47100 -5.09578  1.000 42.80709  ? 75  CYS A O   1 
ATOM   505  C CB  . CYS A 1 76  ? -51.85059 -23.75044 -2.34461  1.000 33.46269  ? 75  CYS A CB  1 
ATOM   506  S SG  . CYS A 1 76  ? -51.20962 -25.41150 -2.66782  1.000 41.55293  ? 75  CYS A SG  1 
ATOM   507  N N   . ILE A 1 77  ? -50.52282 -22.85554 -5.58773  1.000 41.80586  ? 76  ILE A N   1 
ATOM   508  C CA  . ILE A 1 77  ? -50.70629 -22.85129 -7.03862  1.000 42.71831  ? 76  ILE A CA  1 
ATOM   509  C C   . ILE A 1 77  ? -50.34564 -24.21223 -7.60854  1.000 42.02329  ? 76  ILE A C   1 
ATOM   510  O O   . ILE A 1 77  ? -49.23938 -24.71551 -7.39004  1.000 47.01854  ? 76  ILE A O   1 
ATOM   511  C CB  . ILE A 1 77  ? -49.85929 -21.75422 -7.69996  1.000 38.51239  ? 76  ILE A CB  1 
ATOM   512  C CG1 . ILE A 1 77  ? -50.33908 -20.38220 -7.27570  1.000 31.06654  ? 76  ILE A CG1 1 
ATOM   513  C CG2 . ILE A 1 77  ? -49.88014 -21.90308 -9.18222  1.000 37.62430  ? 76  ILE A CG2 1 
ATOM   514  C CD1 . ILE A 1 77  ? -49.36622 -19.35741 -7.64580  1.000 36.64151  ? 76  ILE A CD1 1 
ATOM   515  N N   . ASP A 1 78  ? -51.25822 -24.78652 -8.37459  1.000 39.03769  ? 77  ASP A N   1 
ATOM   516  C CA  . ASP A 1 78  ? -51.03592 -26.09064 -8.98597  1.000 37.14814  ? 77  ASP A CA  1 
ATOM   517  C C   . ASP A 1 78  ? -49.98387 -25.96626 -10.07923 1.000 40.31133  ? 77  ASP A C   1 
ATOM   518  O O   . ASP A 1 78  ? -50.25138 -25.39244 -11.14151 1.000 42.57111  ? 77  ASP A O   1 
ATOM   519  C CB  . ASP A 1 78  ? -52.35274 -26.60771 -9.55174  1.000 40.65763  ? 77  ASP A CB  1 
ATOM   520  C CG  . ASP A 1 78  ? -52.29333 -28.05736 -9.94105  1.000 40.42792  ? 77  ASP A CG  1 
ATOM   521  O OD1 . ASP A 1 78  ? -51.17739 -28.57236 -10.17032 1.000 43.57522  ? 77  ASP A OD1 1 
ATOM   522  O OD2 . ASP A 1 78  ? -53.37441 -28.67686 -10.02804 1.000 37.35939  ? 77  ASP A OD2 1 
ATOM   523  N N   . ALA A 1 79  ? -48.78815 -26.51076 -9.83573  1.000 41.53248  ? 78  ALA A N   1 
ATOM   524  C CA  . ALA A 1 79  ? -47.73755 -26.43876 -10.85044 1.000 38.97669  ? 78  ALA A CA  1 
ATOM   525  C C   . ALA A 1 79  ? -48.14305 -27.16092 -12.12909 1.000 39.94803  ? 78  ALA A C   1 
ATOM   526  O O   . ALA A 1 79  ? -47.83514 -26.70134 -13.23325 1.000 44.65467  ? 78  ALA A O   1 
ATOM   527  C CB  . ALA A 1 79  ? -46.43743 -27.01757 -10.31705 1.000 36.59041  ? 78  ALA A CB  1 
ATOM   528  N N   . ALA A 1 80  ? -48.84724 -28.28049 -12.00813 1.000 31.84474  ? 79  ALA A N   1 
ATOM   529  C CA  . ALA A 1 80  ? -49.24433 -29.01105 -13.19912 1.000 35.99313  ? 79  ALA A CA  1 
ATOM   530  C C   . ALA A 1 80  ? -50.23974 -28.24279 -14.06920 1.000 41.81531  ? 79  ALA A C   1 
ATOM   531  O O   . ALA A 1 80  ? -50.38873 -28.57013 -15.25453 1.000 48.78715  ? 79  ALA A O   1 
ATOM   532  C CB  . ALA A 1 80  ? -49.83274 -30.36336 -12.80549 1.000 42.91190  ? 79  ALA A CB  1 
ATOM   533  N N   . SER A 1 81  ? -50.92416 -27.24335 -13.52020 1.000 36.66297  ? 80  SER A N   1 
ATOM   534  C CA  . SER A 1 81  ? -51.84260 -26.41950 -14.29242 1.000 35.54891  ? 80  SER A CA  1 
ATOM   535  C C   . SER A 1 81  ? -51.17677 -25.17763 -14.87138 1.000 42.20923  ? 80  SER A C   1 
ATOM   536  O O   . SER A 1 81  ? -51.76178 -24.51263 -15.73431 1.000 36.93284  ? 80  SER A O   1 
ATOM   537  C CB  . SER A 1 81  ? -53.01212 -25.98493 -13.41212 1.000 35.88752  ? 80  SER A CB  1 
ATOM   538  O OG  . SER A 1 81  ? -52.62511 -24.94645 -12.52084 1.000 33.55080  ? 80  SER A OG  1 
ATOM   539  N N   . LEU A 1 82  ? -49.96733 -24.86889 -14.42010 1.000 42.95209  ? 81  LEU A N   1 
ATOM   540  C CA  . LEU A 1 82  ? -49.33940 -23.57212 -14.62840 1.000 43.40170  ? 81  LEU A CA  1 
ATOM   541  C C   . LEU A 1 82  ? -48.84693 -23.45130 -16.06355 1.000 42.80546  ? 81  LEU A C   1 
ATOM   542  O O   . LEU A 1 82  ? -47.91422 -24.15526 -16.45789 1.000 46.65216  ? 81  LEU A O   1 
ATOM   543  C CB  . LEU A 1 82  ? -48.19316 -23.42430 -13.63751 1.000 39.29674  ? 81  LEU A CB  1 
ATOM   544  C CG  . LEU A 1 82  ? -47.42754 -22.11972 -13.67813 1.000 36.99390  ? 81  LEU A CG  1 
ATOM   545  C CD1 . LEU A 1 82  ? -48.37384 -20.95714 -13.58687 1.000 34.67734  ? 81  LEU A CD1 1 
ATOM   546  C CD2 . LEU A 1 82  ? -46.42760 -22.11581 -12.55337 1.000 38.58832  ? 81  LEU A CD2 1 
ATOM   547  N N   . ARG A 1 83  ? -49.45090 -22.54234 -16.83776 1.000 49.09083  ? 82  ARG A N   1 
ATOM   548  C CA  . ARG A 1 83  ? -49.15348 -22.36753 -18.26313 1.000 51.52544  ? 82  ARG A CA  1 
ATOM   549  C C   . ARG A 1 83  ? -48.71987 -20.93072 -18.56825 1.000 49.10853  ? 82  ARG A C   1 
ATOM   550  O O   . ARG A 1 83  ? -49.21727 -19.96256 -17.97282 1.000 45.69962  ? 82  ARG A O   1 
ATOM   551  C CB  . ARG A 1 83  ? -50.37132 -22.75370 -19.14585 1.000 36.09525  ? 82  ARG A CB  1 
ATOM   552  C CG  . ARG A 1 83  ? -50.26783 -24.13081 -19.79820 1.000 45.50896  ? 82  ARG A CG  1 
ATOM   553  C CD  . ARG A 1 83  ? -50.86627 -25.23980 -18.90392 1.000 58.52742  ? 82  ARG A CD  1 
ATOM   554  N NE  . ARG A 1 83  ? -50.73318 -26.60889 -19.41962 1.000 66.63860  ? 82  ARG A NE  1 
ATOM   555  C CZ  . ARG A 1 83  ? -49.89766 -27.53393 -18.94849 1.000 64.53017  ? 82  ARG A CZ  1 
ATOM   556  N NH1 . ARG A 1 83  ? -49.04451 -27.27069 -17.96718 1.000 53.06050  ? 82  ARG A NH1 1 
ATOM   557  N NH2 . ARG A 1 83  ? -49.92249 -28.75865 -19.47154 1.000 63.41237  ? 82  ARG A NH2 1 
ATOM   558  N N   . ARG A 1 84  ? -47.78480 -20.79326 -19.50093 1.000 50.54410  ? 83  ARG A N   1 
ATOM   559  C CA  . ARG A 1 84  ? -47.35884 -19.48768 -19.99290 1.000 49.74663  ? 83  ARG A CA  1 
ATOM   560  C C   . ARG A 1 84  ? -47.61369 -19.42496 -21.49516 1.000 52.72420  ? 83  ARG A C   1 
ATOM   561  O O   . ARG A 1 84  ? -47.04130 -20.21107 -22.26862 1.000 48.12272  ? 83  ARG A O   1 
ATOM   562  C CB  . ARG A 1 84  ? -45.88710 -19.23801 -19.67996 1.000 44.73177  ? 83  ARG A CB  1 
ATOM   563  C CG  . ARG A 1 84  ? -45.30472 -18.07574 -20.40143 1.000 39.66779  ? 83  ARG A CG  1 
ATOM   564  C CD  . ARG A 1 84  ? -43.85151 -18.07590 -20.16491 1.000 40.79616  ? 83  ARG A CD  1 
ATOM   565  N NE  . ARG A 1 84  ? -43.22214 -16.88982 -20.70951 1.000 46.15439  ? 83  ARG A NE  1 
ATOM   566  C CZ  . ARG A 1 84  ? -41.93608 -16.82070 -21.01449 1.000 45.43702  ? 83  ARG A CZ  1 
ATOM   567  N NH1 . ARG A 1 84  ? -41.13556 -17.85968 -20.85593 1.000 40.96117  ? 83  ARG A NH1 1 
ATOM   568  N NH2 . ARG A 1 84  ? -41.43774 -15.67552 -21.47224 1.000 44.67257  ? 83  ARG A NH2 1 
ATOM   569  N N   . VAL A 1 85  ? -48.47256 -18.49280 -21.90090 1.000 49.60509  ? 84  VAL A N   1 
ATOM   570  C CA  . VAL A 1 85  ? -48.90228 -18.35491 -23.28421 1.000 48.73071  ? 84  VAL A CA  1 
ATOM   571  C C   . VAL A 1 85  ? -48.56628 -16.94725 -23.74041 1.000 45.79113  ? 84  VAL A C   1 
ATOM   572  O O   . VAL A 1 85  ? -49.17174 -15.97796 -23.26806 1.000 47.43752  ? 84  VAL A O   1 
ATOM   573  C CB  . VAL A 1 85  ? -50.39500 -18.64617 -23.44481 1.000 45.78612  ? 84  VAL A CB  1 
ATOM   574  C CG1 . VAL A 1 85  ? -50.85748 -18.23622 -24.82585 1.000 43.40937  ? 84  VAL A CG1 1 
ATOM   575  C CG2 . VAL A 1 85  ? -50.65616 -20.13051 -23.17445 1.000 39.77119  ? 84  VAL A CG2 1 
ATOM   576  N N   . ARG A 1 86  ? -47.59016 -16.83748 -24.64366 1.000 48.30758  ? 85  ARG A N   1 
ATOM   577  C CA  . ARG A 1 86  ? -47.16857 -15.57914 -25.25052 1.000 52.22317  ? 85  ARG A CA  1 
ATOM   578  C C   . ARG A 1 86  ? -47.51230 -15.61892 -26.73323 1.000 57.91090  ? 85  ARG A C   1 
ATOM   579  O O   . ARG A 1 86  ? -47.12297 -16.56041 -27.43590 1.000 53.08383  ? 85  ARG A O   1 
ATOM   580  C CB  . ARG A 1 86  ? -45.66844 -15.34958 -25.04741 1.000 50.99201  ? 85  ARG A CB  1 
ATOM   581  C CG  . ARG A 1 86  ? -45.09693 -14.02325 -25.54955 1.000 56.05910  ? 85  ARG A CG  1 
ATOM   582  C CD  . ARG A 1 86  ? -44.70018 -14.12427 -27.02299 1.000 66.14348  ? 85  ARG A CD  1 
ATOM   583  N NE  . ARG A 1 86  ? -43.46176 -13.44053 -27.39551 1.000 73.92408  ? 85  ARG A NE  1 
ATOM   584  C CZ  . ARG A 1 86  ? -43.26035 -12.12817 -27.35146 1.000 81.33571  ? 85  ARG A CZ  1 
ATOM   585  N NH1 . ARG A 1 86  ? -44.18129 -11.29751 -26.88181 1.000 80.44229  ? 85  ARG A NH1 1 
ATOM   586  N NH2 . ARG A 1 86  ? -42.10831 -11.63347 -27.80314 1.000 82.13778  ? 85  ARG A NH2 1 
ATOM   587  N N   . LYS A 1 87  ? -48.23783 -14.59136 -27.19917 1.000 62.86270  ? 86  LYS A N   1 
ATOM   588  C CA  . LYS A 1 87  ? -48.74758 -14.49292 -28.56785 1.000 58.17946  ? 86  LYS A CA  1 
ATOM   589  C C   . LYS A 1 87  ? -49.32522 -15.81991 -29.03665 1.000 63.03824  ? 86  LYS A C   1 
ATOM   590  O O   . LYS A 1 87  ? -49.08117 -16.22683 -30.17844 1.000 63.53724  ? 86  LYS A O   1 
ATOM   591  C CB  . LYS A 1 87  ? -47.65743 -14.05350 -29.55216 1.000 54.94354  ? 86  LYS A CB  1 
ATOM   592  C CG  . LYS A 1 87  ? -47.54884 -12.55167 -29.80300 1.000 65.22358  ? 86  LYS A CG  1 
ATOM   593  C CD  . LYS A 1 87  ? -46.11367 -12.08324 -29.58606 1.000 69.20617  ? 86  LYS A CD  1 
ATOM   594  C CE  . LYS A 1 87  ? -45.83471 -10.72924 -30.21458 1.000 74.05780  ? 86  LYS A CE  1 
ATOM   595  N NZ  . LYS A 1 87  ? -44.36628 -10.45394 -30.26737 1.000 76.31752  ? 86  LYS A NZ  1 
ATOM   596  N N   . GLY A 1 88  ? -50.06369 -16.51269 -28.16332 1.000 58.43198  ? 87  GLY A N   1 
ATOM   597  C CA  . GLY A 1 88  ? -50.66485 -17.78452 -28.51679 1.000 56.52173  ? 87  GLY A CA  1 
ATOM   598  C C   . GLY A 1 88  ? -49.71419 -18.95885 -28.62028 1.000 58.86896  ? 87  GLY A C   1 
ATOM   599  O O   . GLY A 1 88  ? -50.16653 -20.07335 -28.92291 1.000 62.62231  ? 87  GLY A O   1 
ATOM   600  N N   . GLU A 1 89  ? -48.41753 -18.75322 -28.39790 1.000 53.73927  ? 88  GLU A N   1 
ATOM   601  C CA  . GLU A 1 89  ? -47.46672 -19.85202 -28.28564 1.000 59.75552  ? 88  GLU A CA  1 
ATOM   602  C C   . GLU A 1 89  ? -47.28131 -20.23162 -26.81250 1.000 53.42789  ? 88  GLU A C   1 
ATOM   603  O O   . GLU A 1 89  ? -47.21743 -19.36191 -25.94046 1.000 56.14272  ? 88  GLU A O   1 
ATOM   604  C CB  . GLU A 1 89  ? -46.13010 -19.45504 -28.92117 1.000 50.22072  ? 88  GLU A CB  1 
ATOM   605  N N   . GLU A 1 90  ? -47.21585 -21.53137 -26.52926 1.000 50.91178  ? 89  GLU A N   1 
ATOM   606  C CA  . GLU A 1 90  ? -47.05769 -22.00276 -25.15517 1.000 52.27783  ? 89  GLU A CA  1 
ATOM   607  C C   . GLU A 1 90  ? -45.57413 -22.09446 -24.82155 1.000 51.19378  ? 89  GLU A C   1 
ATOM   608  O O   . GLU A 1 90  ? -44.82362 -22.78917 -25.51269 1.000 46.93873  ? 89  GLU A O   1 
ATOM   609  C CB  . GLU A 1 90  ? -47.73435 -23.35457 -24.94338 1.000 42.34579  ? 89  GLU A CB  1 
ATOM   610  C CG  . GLU A 1 90  ? -48.24190 -23.51606 -23.53168 1.000 54.43347  ? 89  GLU A CG  1 
ATOM   611  C CD  . GLU A 1 90  ? -48.60714 -24.94936 -23.18120 1.000 66.60198  ? 89  GLU A CD  1 
ATOM   612  O OE1 . GLU A 1 90  ? -49.10677 -25.67739 -24.07114 1.000 64.55982  ? 89  GLU A OE1 1 
ATOM   613  O OE2 . GLU A 1 90  ? -48.39618 -25.34566 -22.00687 1.000 68.85506  ? 89  GLU A OE2 1 
ATOM   614  N N   . LEU A 1 91  ? -45.15627 -21.41521 -23.75657 1.000 46.40032  ? 90  LEU A N   1 
ATOM   615  C CA  . LEU A 1 91  ? -43.74383 -21.29377 -23.43627 1.000 43.98099  ? 90  LEU A CA  1 
ATOM   616  C C   . LEU A 1 91  ? -43.38610 -22.04188 -22.15760 1.000 43.31639  ? 90  LEU A C   1 
ATOM   617  O O   . LEU A 1 91  ? -44.24942 -22.37575 -21.34245 1.000 50.93401  ? 90  LEU A O   1 
ATOM   618  C CB  . LEU A 1 91  ? -43.36188 -19.82212 -23.29526 1.000 50.11855  ? 90  LEU A CB  1 
ATOM   619  C CG  . LEU A 1 91  ? -43.55450 -19.04834 -24.59781 1.000 53.94671  ? 90  LEU A CG  1 
ATOM   620  C CD1 . LEU A 1 91  ? -42.93778 -17.62658 -24.54118 1.000 45.09437  ? 90  LEU A CD1 1 
ATOM   621  C CD2 . LEU A 1 91  ? -42.99580 -19.86842 -25.75753 1.000 44.43840  ? 90  LEU A CD2 1 
ATOM   622  N N   . ARG A 1 92  ? -42.09146 -22.30611 -21.99075 1.000 40.16123  ? 91  ARG A N   1 
ATOM   623  C CA  . ARG A 1 92  ? -41.59831 -22.75338 -20.69616 1.000 37.53768  ? 91  ARG A CA  1 
ATOM   624  C C   . ARG A 1 92  ? -41.83409 -21.66847 -19.66122 1.000 43.28169  ? 91  ARG A C   1 
ATOM   625  O O   . ARG A 1 92  ? -41.66897 -20.47748 -19.93454 1.000 43.81837  ? 91  ARG A O   1 
ATOM   626  C CB  . ARG A 1 92  ? -40.10430 -23.08702 -20.75292 1.000 38.93026  ? 91  ARG A CB  1 
ATOM   627  N N   . ILE A 1 93  ? -42.27517 -22.09218 -18.47992 1.000 53.05539  ? 92  ILE A N   1 
ATOM   628  C CA  . ILE A 1 93  ? -42.29570 -21.23460 -17.29969 1.000 43.24743  ? 92  ILE A CA  1 
ATOM   629  C C   . ILE A 1 93  ? -40.87566 -20.77257 -17.00755 1.000 44.02821  ? 92  ILE A C   1 
ATOM   630  O O   . ILE A 1 93  ? -39.97795 -21.59114 -16.77414 1.000 48.40798  ? 92  ILE A O   1 
ATOM   631  C CB  . ILE A 1 93  ? -42.89223 -22.00579 -16.11946 1.000 41.13206  ? 92  ILE A CB  1 
ATOM   632  C CG1 . ILE A 1 93  ? -44.35909 -22.29202 -16.40256 1.000 47.94315  ? 92  ILE A CG1 1 
ATOM   633  C CG2 . ILE A 1 93  ? -42.69183 -21.28919 -14.81777 1.000 39.62562  ? 92  ILE A CG2 1 
ATOM   634  C CD1 . ILE A 1 93  ? -45.23238 -21.10159 -16.16136 1.000 50.94531  ? 92  ILE A CD1 1 
ATOM   635  N N   . ASP A 1 94  ? -40.65493 -19.46467 -17.02385 1.000 38.64119  ? 93  ASP A N   1 
ATOM   636  C CA  . ASP A 1 94  ? -39.34298 -18.92441 -16.70146 1.000 40.32920  ? 93  ASP A CA  1 
ATOM   637  C C   . ASP A 1 94  ? -39.47586 -17.81039 -15.67185 1.000 44.45908  ? 93  ASP A C   1 
ATOM   638  O O   . ASP A 1 94  ? -40.25800 -16.87208 -15.86289 1.000 41.68764  ? 93  ASP A O   1 
ATOM   639  C CB  . ASP A 1 94  ? -38.64427 -18.40662 -17.94814 1.000 42.97022  ? 93  ASP A CB  1 
ATOM   640  C CG  . ASP A 1 94  ? -37.26000 -17.87428 -17.65051 1.000 48.99668  ? 93  ASP A CG  1 
ATOM   641  O OD1 . ASP A 1 94  ? -36.31759 -18.69659 -17.55001 1.000 52.91403  ? 93  ASP A OD1 1 
ATOM   642  O OD2 . ASP A 1 94  ? -37.11348 -16.63600 -17.50858 1.000 47.22418  ? 93  ASP A OD2 1 
ATOM   643  N N   . ALA A 1 95  ? -38.68411 -17.89700 -14.59722 1.000 44.62927  ? 94  ALA A N   1 
ATOM   644  C CA  . ALA A 1 95  ? -38.87485 -16.98449 -13.47257 1.000 43.31985  ? 94  ALA A CA  1 
ATOM   645  C C   . ALA A 1 95  ? -38.37676 -15.57316 -13.78992 1.000 40.78119  ? 94  ALA A C   1 
ATOM   646  O O   . ALA A 1 95  ? -39.03746 -14.58573 -13.44317 1.000 40.98506  ? 94  ALA A O   1 
ATOM   647  C CB  . ALA A 1 95  ? -38.19115 -17.54594 -12.22250 1.000 38.29913  ? 94  ALA A CB  1 
ATOM   648  N N   . ILE A 1 96  ? -37.21468 -15.44634 -14.43296 1.000 39.76742  ? 95  ILE A N   1 
ATOM   649  C CA  . ILE A 1 96  ? -36.71657 -14.11498 -14.77104 1.000 39.13947  ? 95  ILE A CA  1 
ATOM   650  C C   . ILE A 1 96  ? -37.68972 -13.41148 -15.71517 1.000 45.40547  ? 95  ILE A C   1 
ATOM   651  O O   . ILE A 1 96  ? -38.12732 -12.27945 -15.45300 1.000 43.78679  ? 95  ILE A O   1 
ATOM   652  C CB  . ILE A 1 96  ? -35.30179 -14.20094 -15.36573 1.000 33.46058  ? 95  ILE A CB  1 
ATOM   653  C CG1 . ILE A 1 96  ? -34.29033 -14.46257 -14.25382 1.000 36.09315  ? 95  ILE A CG1 1 
ATOM   654  C CG2 . ILE A 1 96  ? -34.94956 -12.91347 -16.02647 1.000 29.86454  ? 95  ILE A CG2 1 
ATOM   655  C CD1 . ILE A 1 96  ? -32.90762 -14.92524 -14.72898 1.000 33.69651  ? 95  ILE A CD1 1 
ATOM   656  N N   . ASP A 1 97  ? -38.06241 -14.08939 -16.81541 1.000 40.78284  ? 96  ASP A N   1 
ATOM   657  C CA  . ASP A 1 97  ? -39.09383 -13.58786 -17.72810 1.000 39.77211  ? 96  ASP A CA  1 
ATOM   658  C C   . ASP A 1 97  ? -40.31235 -13.08777 -16.96983 1.000 40.98277  ? 96  ASP A C   1 
ATOM   659  O O   . ASP A 1 97  ? -40.88289 -12.04866 -17.31065 1.000 41.87807  ? 96  ASP A O   1 
ATOM   660  C CB  . ASP A 1 97  ? -39.52860 -14.68975 -18.70434 1.000 44.61930  ? 96  ASP A CB  1 
ATOM   661  C CG  . ASP A 1 97  ? -38.49347 -14.97454 -19.82532 1.000 56.13285  ? 96  ASP A CG  1 
ATOM   662  O OD1 . ASP A 1 97  ? -37.51953 -14.19839 -20.02465 1.000 52.47337  ? 96  ASP A OD1 1 
ATOM   663  O OD2 . ASP A 1 97  ? -38.67294 -16.00375 -20.52469 1.000 60.72955  ? 96  ASP A OD2 1 
ATOM   664  N N   . LEU A 1 98  ? -40.71614 -13.81974 -15.92639 1.000 46.69060  ? 97  LEU A N   1 
ATOM   665  C CA  . LEU A 1 98  ? -41.88615 -13.45044 -15.12810 1.000 43.56936  ? 97  LEU A CA  1 
ATOM   666  C C   . LEU A 1 98  ? -41.69746 -12.10095 -14.45237 1.000 42.01389  ? 97  LEU A C   1 
ATOM   667  O O   . LEU A 1 98  ? -42.59438 -11.25176 -14.48476 1.000 42.79473  ? 97  LEU A O   1 
ATOM   668  C CB  . LEU A 1 98  ? -42.16803 -14.53460 -14.08505 1.000 43.77153  ? 97  LEU A CB  1 
ATOM   669  C CG  . LEU A 1 98  ? -43.48547 -14.44201 -13.33241 1.000 37.41393  ? 97  LEU A CG  1 
ATOM   670  C CD1 . LEU A 1 98  ? -44.56430 -14.22690 -14.33210 1.000 36.10171  ? 97  LEU A CD1 1 
ATOM   671  C CD2 . LEU A 1 98  ? -43.72599 -15.74054 -12.60252 1.000 39.17791  ? 97  LEU A CD2 1 
ATOM   672  N N   . ILE A 1 99  ? -40.53484 -11.88313 -13.83230 1.000 39.12729  ? 98  ILE A N   1 
ATOM   673  C CA  . ILE A 1 99  ? -40.27181 -10.59142 -13.20468 1.000 38.95883  ? 98  ILE A CA  1 
ATOM   674  C C   . ILE A 1 99  ? -40.24431 -9.48002  -14.23846 1.000 43.44121  ? 98  ILE A C   1 
ATOM   675  O O   . ILE A 1 99  ? -40.78617 -8.39330  -14.00586 1.000 43.88440  ? 98  ILE A O   1 
ATOM   676  C CB  . ILE A 1 99  ? -38.95658 -10.62578 -12.42253 1.000 40.03263  ? 98  ILE A CB  1 
ATOM   677  C CG1 . ILE A 1 99  ? -38.87642 -11.92609 -11.61555 1.000 42.03552  ? 98  ILE A CG1 1 
ATOM   678  C CG2 . ILE A 1 99  ? -38.85171 -9.36530  -11.60157 1.000 25.67075  ? 98  ILE A CG2 1 
ATOM   679  C CD1 . ILE A 1 99  ? -38.61015 -11.73690 -10.16482 1.000 40.09630  ? 98  ILE A CD1 1 
ATOM   680  N N   . VAL A 1 100 ? -39.58938 -9.71596  -15.38481 1.000 42.42086  ? 99  VAL A N   1 
ATOM   681  C CA  . VAL A 1 100 ? -39.51516 -8.68073  -16.41917 1.000 43.11443  ? 99  VAL A CA  1 
ATOM   682  C C   . VAL A 1 100 ? -40.91701 -8.36388  -16.95027 1.000 44.84643  ? 99  VAL A C   1 
ATOM   683  O O   . VAL A 1 100 ? -41.31237 -7.19353  -17.06557 1.000 40.82813  ? 99  VAL A O   1 
ATOM   684  C CB  . VAL A 1 100 ? -38.55123 -9.10882  -17.54679 1.000 43.07709  ? 99  VAL A CB  1 
ATOM   685  C CG1 . VAL A 1 100 ? -38.32432 -7.97431  -18.53161 1.000 33.54313  ? 99  VAL A CG1 1 
ATOM   686  C CG2 . VAL A 1 100 ? -37.22056 -9.55218  -16.98496 1.000 37.82929  ? 99  VAL A CG2 1 
ATOM   687  N N   . ASP A 1 101 ? -41.70132 -9.41118  -17.24548 1.000 40.87948  ? 100 ASP A N   1 
ATOM   688  C CA  . ASP A 1 101 ? -43.09891 -9.25950  -17.63692 1.000 39.37857  ? 100 ASP A CA  1 
ATOM   689  C C   . ASP A 1 101 ? -43.90116 -8.41059  -16.65582 1.000 48.67059  ? 100 ASP A C   1 
ATOM   690  O O   . ASP A 1 101 ? -44.97541 -7.91013  -17.01303 1.000 52.17453  ? 100 ASP A O   1 
ATOM   691  C CB  . ASP A 1 101 ? -43.75869 -10.63207 -17.73047 1.000 38.75126  ? 100 ASP A CB  1 
ATOM   692  C CG  . ASP A 1 101 ? -43.59764 -11.27635 -19.07490 1.000 46.53615  ? 100 ASP A CG  1 
ATOM   693  O OD1 . ASP A 1 101 ? -43.15497 -10.59793 -20.03508 1.000 56.73570  ? 100 ASP A OD1 1 
ATOM   694  O OD2 . ASP A 1 101 ? -43.92473 -12.48101 -19.16600 1.000 47.25272  ? 100 ASP A OD2 1 
ATOM   695  N N   . MET A 1 102 ? -43.41876 -8.24479  -15.42276 1.000 49.08878  ? 101 MET A N   1 
ATOM   696  C CA  . MET A 1 102 ? -44.21489 -7.64406  -14.36504 1.000 50.36327  ? 101 MET A CA  1 
ATOM   697  C C   . MET A 1 102 ? -43.58746 -6.40936  -13.73412 1.000 48.00084  ? 101 MET A C   1 
ATOM   698  O O   . MET A 1 102 ? -44.21739 -5.81138  -12.85913 1.000 47.58223  ? 101 MET A O   1 
ATOM   699  C CB  . MET A 1 102 ? -44.47457 -8.67150  -13.25840 1.000 51.20837  ? 101 MET A CB  1 
ATOM   700  C CG  . MET A 1 102 ? -45.37911 -9.82045  -13.66115 1.000 52.35992  ? 101 MET A CG  1 
ATOM   701  S SD  . MET A 1 102 ? -47.04838 -9.33476  -14.15427 1.000 68.82398  ? 101 MET A SD  1 
ATOM   702  C CE  . MET A 1 102 ? -47.32310 -10.55744 -15.42462 1.000 51.81990  ? 101 MET A CE  1 
ATOM   703  N N   . SER A 1 103 ? -42.37737 -6.01449  -14.15234 1.000 46.33928  ? 102 SER A N   1 
ATOM   704  C CA  . SER A 1 103 ? -41.63651 -4.93469  -13.49371 1.000 50.27668  ? 102 SER A CA  1 
ATOM   705  C C   . SER A 1 103 ? -42.50169 -3.70816  -13.21887 1.000 51.99560  ? 102 SER A C   1 
ATOM   706  O O   . SER A 1 103 ? -42.40486 -3.09714  -12.14718 1.000 54.52145  ? 102 SER A O   1 
ATOM   707  C CB  . SER A 1 103 ? -40.44535 -4.53976  -14.35699 1.000 47.81626  ? 102 SER A CB  1 
ATOM   708  O OG  . SER A 1 103 ? -40.82570 -4.59566  -15.72359 1.000 58.93580  ? 102 SER A OG  1 
ATOM   709  N N   . GLY A 1 104 ? -43.34723 -3.33329  -14.17436 1.000 48.50384  ? 103 GLY A N   1 
ATOM   710  C CA  . GLY A 1 104 ? -44.22416 -2.19243  -14.01552 1.000 50.99409  ? 103 GLY A CA  1 
ATOM   711  C C   . GLY A 1 104 ? -45.23884 -2.34258  -12.90161 1.000 52.98664  ? 103 GLY A C   1 
ATOM   712  O O   . GLY A 1 104 ? -45.23711 -1.57303  -11.93803 1.000 60.79606  ? 103 GLY A O   1 
ATOM   713  N N   . SER A 1 105 ? -46.10887 -3.34177  -13.02149 1.000 51.96252  ? 104 SER A N   1 
ATOM   714  C CA  . SER A 1 105 ? -47.09134 -3.62646  -11.98321 1.000 54.22739  ? 104 SER A CA  1 
ATOM   715  C C   . SER A 1 105 ? -46.46330 -3.79653  -10.59653 1.000 55.59055  ? 104 SER A C   1 
ATOM   716  O O   . SER A 1 105 ? -47.17403 -3.72487  -9.58958  1.000 59.61320  ? 104 SER A O   1 
ATOM   717  C CB  . SER A 1 105 ? -47.86642 -4.89339  -12.36524 1.000 58.41760  ? 104 SER A CB  1 
ATOM   718  O OG  . SER A 1 105 ? -48.12437 -4.94396  -13.76571 1.000 53.96525  ? 104 SER A OG  1 
ATOM   719  N N   . LEU A 1 106 ? -45.15603 -4.02826  -10.51512 1.000 54.25115  ? 105 LEU A N   1 
ATOM   720  C CA  . LEU A 1 106 ? -44.49471 -4.26427  -9.24193  1.000 52.24547  ? 105 LEU A CA  1 
ATOM   721  C C   . LEU A 1 106 ? -43.97416 -2.99364  -8.60168  1.000 57.53447  ? 105 LEU A C   1 
ATOM   722  O O   . LEU A 1 106 ? -43.48975 -3.04332  -7.46294  1.000 57.52712  ? 105 LEU A O   1 
ATOM   723  C CB  . LEU A 1 106 ? -43.32147 -5.22853  -9.41900  1.000 50.59625  ? 105 LEU A CB  1 
ATOM   724  C CG  . LEU A 1 106 ? -43.69977 -6.67243  -9.70709  1.000 49.10856  ? 105 LEU A CG  1 
ATOM   725  C CD1 . LEU A 1 106 ? -42.44088 -7.46969  -9.87565  1.000 46.99356  ? 105 LEU A CD1 1 
ATOM   726  C CD2 . LEU A 1 106 ? -44.55528 -7.23656  -8.59380  1.000 45.46651  ? 105 LEU A CD2 1 
ATOM   727  N N   . GLY A 1 107 ? -44.03801 -1.86978  -9.30373  1.000 54.22478  ? 106 GLY A N   1 
ATOM   728  C CA  . GLY A 1 107 ? -43.47218 -0.65497  -8.76281  1.000 62.15372  ? 106 GLY A CA  1 
ATOM   729  C C   . GLY A 1 107 ? -41.96838 -0.74862  -8.61332  1.000 65.28716  ? 106 GLY A C   1 
ATOM   730  O O   . GLY A 1 107 ? -41.39069 -0.40243  -7.57333  1.000 63.11258  ? 106 GLY A O   1 
ATOM   731  N N   . ILE A 1 108 ? -41.31352 -1.24212  -9.65691  1.000 59.31320  ? 107 ILE A N   1 
ATOM   732  C CA  . ILE A 1 108 ? -39.86208 -1.17319  -9.74499  1.000 61.08967  ? 107 ILE A CA  1 
ATOM   733  C C   . ILE A 1 108 ? -39.52391 0.00665   -10.65244 1.000 58.87112  ? 107 ILE A C   1 
ATOM   734  O O   . ILE A 1 108 ? -39.89202 -0.01620  -11.83768 1.000 53.76269  ? 107 ILE A O   1 
ATOM   735  C CB  . ILE A 1 108 ? -39.25646 -2.48232  -10.26366 1.000 58.02928  ? 107 ILE A CB  1 
ATOM   736  C CG1 . ILE A 1 108 ? -39.44588 -3.58911  -9.22488  1.000 58.73269  ? 107 ILE A CG1 1 
ATOM   737  C CG2 . ILE A 1 108 ? -37.77613 -2.29557  -10.53709 1.000 54.89736  ? 107 ILE A CG2 1 
ATOM   738  C CD1 . ILE A 1 108 ? -39.43647 -4.99195  -9.78803  1.000 51.31369  ? 107 ILE A CD1 1 
ATOM   739  N N   . PRO A 1 109 ? -38.90463 1.06686   -10.13512 1.000 60.15431  ? 108 PRO A N   1 
ATOM   740  C CA  . PRO A 1 109 ? -38.37185 2.12139   -11.00820 1.000 58.70637  ? 108 PRO A CA  1 
ATOM   741  C C   . PRO A 1 109 ? -37.46769 1.55391   -12.09591 1.000 61.25165  ? 108 PRO A C   1 
ATOM   742  O O   . PRO A 1 109 ? -36.54785 0.77652   -11.81761 1.000 58.71675  ? 108 PRO A O   1 
ATOM   743  C CB  . PRO A 1 109 ? -37.59034 3.01392   -10.03553 1.000 59.05657  ? 108 PRO A CB  1 
ATOM   744  C CG  . PRO A 1 109 ? -38.30606 2.85997   -8.73870  1.000 59.30141  ? 108 PRO A CG  1 
ATOM   745  C CD  . PRO A 1 109 ? -38.81127 1.42330   -8.70773  1.000 61.49093  ? 108 PRO A CD  1 
ATOM   746  N N   . VAL A 1 110 ? -37.73903 1.95777   -13.34853 1.000 60.14717  ? 109 VAL A N   1 
ATOM   747  C CA  . VAL A 1 110 ? -36.94367 1.54207   -14.51012 1.000 57.14051  ? 109 VAL A CA  1 
ATOM   748  C C   . VAL A 1 110 ? -35.45881 1.76018   -14.26571 1.000 58.43619  ? 109 VAL A C   1 
ATOM   749  O O   . VAL A 1 110 ? -34.61472 1.05040   -14.82968 1.000 55.19359  ? 109 VAL A O   1 
ATOM   750  C CB  . VAL A 1 110 ? -37.41642 2.29180   -15.77889 1.000 52.37545  ? 109 VAL A CB  1 
ATOM   751  C CG1 . VAL A 1 110 ? -37.03549 3.75442   -15.70003 1.000 53.32613  ? 109 VAL A CG1 1 
ATOM   752  C CG2 . VAL A 1 110 ? -36.82214 1.66771   -17.02579 1.000 49.87200  ? 109 VAL A CG2 1 
ATOM   753  N N   . ASP A 1 111 ? -35.11737 2.75259   -13.43626 1.000 58.83880  ? 110 ASP A N   1 
ATOM   754  C CA  . ASP A 1 111 ? -33.74818 2.90308   -12.96726 1.000 56.16686  ? 110 ASP A CA  1 
ATOM   755  C C   . ASP A 1 111 ? -33.28484 1.65375   -12.22764 1.000 60.49994  ? 110 ASP A C   1 
ATOM   756  O O   . ASP A 1 111 ? -32.12843 1.23234   -12.36696 1.000 59.45346  ? 110 ASP A O   1 
ATOM   757  C CB  . ASP A 1 111 ? -33.65326 4.13343   -12.06159 1.000 60.59783  ? 110 ASP A CB  1 
ATOM   758  N N   . ALA A 1 112 ? -34.18736 1.02990   -11.45579 1.000 60.78388  ? 111 ALA A N   1 
ATOM   759  C CA  . ALA A 1 112 ? -33.82310 -0.04495  -10.53600 1.000 59.49634  ? 111 ALA A CA  1 
ATOM   760  C C   . ALA A 1 112 ? -33.89398 -1.44536  -11.14119 1.000 56.28970  ? 111 ALA A C   1 
ATOM   761  O O   . ALA A 1 112 ? -33.30730 -2.37060  -10.56445 1.000 49.96898  ? 111 ALA A O   1 
ATOM   762  C CB  . ALA A 1 112 ? -34.72011 0.00296   -9.29283  1.000 54.25127  ? 111 ALA A CB  1 
ATOM   763  N N   . LEU A 1 113 ? -34.58147 -1.62741  -12.27611 1.000 53.18759  ? 112 LEU A N   1 
ATOM   764  C CA  . LEU A 1 113 ? -34.81699 -2.97920  -12.78155 1.000 47.66211  ? 112 LEU A CA  1 
ATOM   765  C C   . LEU A 1 113 ? -33.55816 -3.76430  -13.12137 1.000 47.13882  ? 112 LEU A C   1 
ATOM   766  O O   . LEU A 1 113 ? -33.51808 -4.96673  -12.80662 1.000 50.07499  ? 112 LEU A O   1 
ATOM   767  C CB  . LEU A 1 113 ? -35.73543 -2.95491  -14.00077 1.000 41.81497  ? 112 LEU A CB  1 
ATOM   768  C CG  . LEU A 1 113 ? -36.19867 -4.39408  -14.19495 1.000 40.28367  ? 112 LEU A CG  1 
ATOM   769  C CD1 . LEU A 1 113 ? -37.13259 -4.77830  -13.06801 1.000 42.82888  ? 112 LEU A CD1 1 
ATOM   770  C CD2 . LEU A 1 113 ? -36.86110 -4.61833  -15.51806 1.000 41.12987  ? 112 LEU A CD2 1 
ATOM   771  N N   . PRO A 1 114 ? -32.52541 -3.20278  -13.74551 1.000 49.73978  ? 113 PRO A N   1 
ATOM   772  C CA  . PRO A 1 114 ? -31.34894 -4.04829  -14.01545 1.000 54.10705  ? 113 PRO A CA  1 
ATOM   773  C C   . PRO A 1 114 ? -30.68398 -4.52134  -12.73646 1.000 47.26488  ? 113 PRO A C   1 
ATOM   774  O O   . PRO A 1 114 ? -30.30209 -5.69491  -12.63578 1.000 40.81825  ? 113 PRO A O   1 
ATOM   775  C CB  . PRO A 1 114 ? -30.43374 -3.13593  -14.85515 1.000 50.81500  ? 113 PRO A CB  1 
ATOM   776  C CG  . PRO A 1 114 ? -31.32725 -2.00154  -15.31242 1.000 54.76954  ? 113 PRO A CG  1 
ATOM   777  C CD  . PRO A 1 114 ? -32.29215 -1.81604  -14.17775 1.000 51.87785  ? 113 PRO A CD  1 
ATOM   778  N N   . GLU A 1 115 ? -30.57278 -3.63145  -11.74157 1.000 49.95814  ? 114 GLU A N   1 
ATOM   779  C CA  . GLU A 1 115 ? -29.94896 -3.98526  -10.47014 1.000 43.54597  ? 114 GLU A CA  1 
ATOM   780  C C   . GLU A 1 115 ? -30.71963 -5.09272  -9.77261  1.000 45.65913  ? 114 GLU A C   1 
ATOM   781  O O   . GLU A 1 115 ? -30.12905 -6.05630  -9.27065  1.000 42.43591  ? 114 GLU A O   1 
ATOM   782  C CB  . GLU A 1 115 ? -29.86905 -2.75197  -9.57766  1.000 45.95377  ? 114 GLU A CB  1 
ATOM   783  N N   . TYR A 1 116 ? -32.04648 -4.97688  -9.74447  1.000 49.62463  ? 115 TYR A N   1 
ATOM   784  C CA  . TYR A 1 116 ? -32.86827 -6.01104  -9.13436  1.000 41.73646  ? 115 TYR A CA  1 
ATOM   785  C C   . TYR A 1 116 ? -32.68379 -7.34376  -9.84556  1.000 41.03936  ? 115 TYR A C   1 
ATOM   786  O O   . TYR A 1 116 ? -32.44156 -8.37437  -9.20628  1.000 43.31498  ? 115 TYR A O   1 
ATOM   787  C CB  . TYR A 1 116 ? -34.32923 -5.58833  -9.15770  1.000 40.11891  ? 115 TYR A CB  1 
ATOM   788  C CG  . TYR A 1 116 ? -35.19448 -6.57271  -8.43927  1.000 45.70969  ? 115 TYR A CG  1 
ATOM   789  C CD1 . TYR A 1 116 ? -35.15235 -6.66505  -7.05040  1.000 39.23125  ? 115 TYR A CD1 1 
ATOM   790  C CD2 . TYR A 1 116 ? -36.01966 -7.45581  -9.14650  1.000 40.46742  ? 115 TYR A CD2 1 
ATOM   791  C CE1 . TYR A 1 116 ? -35.93040 -7.58120  -6.37781  1.000 41.46388  ? 115 TYR A CE1 1 
ATOM   792  C CE2 . TYR A 1 116 ? -36.80461 -8.37664  -8.48170  1.000 37.48533  ? 115 TYR A CE2 1 
ATOM   793  C CZ  . TYR A 1 116 ? -36.75764 -8.42975  -7.09809  1.000 43.34562  ? 115 TYR A CZ  1 
ATOM   794  O OH  . TYR A 1 116 ? -37.53255 -9.33474  -6.42256  1.000 47.71211  ? 115 TYR A OH  1 
ATOM   795  N N   . LEU A 1 117 ? -32.77232 -7.33586  -11.17690 1.000 41.22878  ? 116 LEU A N   1 
ATOM   796  C CA  . LEU A 1 117 ? -32.58214 -8.56005  -11.94812 1.000 40.01159  ? 116 LEU A CA  1 
ATOM   797  C C   . LEU A 1 117 ? -31.24678 -9.24007  -11.64618 1.000 40.43401  ? 116 LEU A C   1 
ATOM   798  O O   . LEU A 1 117 ? -31.17246 -10.47345 -11.59691 1.000 37.96828  ? 116 LEU A O   1 
ATOM   799  C CB  . LEU A 1 117 ? -32.69816 -8.25165  -13.43221 1.000 39.80069  ? 116 LEU A CB  1 
ATOM   800  C CG  . LEU A 1 117 ? -34.05389 -8.64666  -13.99363 1.000 37.54161  ? 116 LEU A CG  1 
ATOM   801  C CD1 . LEU A 1 117 ? -34.07275 -8.33052  -15.46267 1.000 42.83107  ? 116 LEU A CD1 1 
ATOM   802  C CD2 . LEU A 1 117 ? -34.27712 -10.11782 -13.75506 1.000 35.31177  ? 116 LEU A CD2 1 
ATOM   803  N N   . GLU A 1 118 ? -30.17727 -8.46545  -11.44001 1.000 41.64133  ? 117 GLU A N   1 
ATOM   804  C CA  . GLU A 1 118 ? -28.91595 -9.09439  -11.05702 1.000 38.16545  ? 117 GLU A CA  1 
ATOM   805  C C   . GLU A 1 118 ? -29.06627 -9.82681  -9.74173  1.000 41.34295  ? 117 GLU A C   1 
ATOM   806  O O   . GLU A 1 118 ? -28.72176 -11.00988 -9.63612  1.000 42.76562  ? 117 GLU A O   1 
ATOM   807  C CB  . GLU A 1 118 ? -27.77833 -8.08356  -10.94080 1.000 39.19134  ? 117 GLU A CB  1 
ATOM   808  C CG  . GLU A 1 118 ? -26.49412 -8.78653  -10.48521 1.000 42.31277  ? 117 GLU A CG  1 
ATOM   809  C CD  . GLU A 1 118 ? -25.28630 -7.86876  -10.38167 1.000 47.62321  ? 117 GLU A CD  1 
ATOM   810  O OE1 . GLU A 1 118 ? -25.37089 -6.74224  -10.91795 1.000 46.22561  ? 117 GLU A OE1 1 
ATOM   811  O OE2 . GLU A 1 118 ? -24.25163 -8.29181  -9.78828  1.000 45.93397  ? 117 GLU A OE2 1 
ATOM   812  N N   . GLU A 1 119 ? -29.56881 -9.12339  -8.72015  1.000 44.54826  ? 118 GLU A N   1 
ATOM   813  C CA  . GLU A 1 119 ? -29.80948 -9.73686  -7.41982  1.000 40.75218  ? 118 GLU A CA  1 
ATOM   814  C C   . GLU A 1 119 ? -30.61005 -11.01223 -7.58395  1.000 39.61828  ? 118 GLU A C   1 
ATOM   815  O O   . GLU A 1 119 ? -30.22934 -12.07057 -7.07557  1.000 41.94832  ? 118 GLU A O   1 
ATOM   816  C CB  . GLU A 1 119 ? -30.54330 -8.75328  -6.50489  1.000 41.66526  ? 118 GLU A CB  1 
ATOM   817  C CG  . GLU A 1 119 ? -30.43362 -9.04825  -5.01733  1.000 46.13886  ? 118 GLU A CG  1 
ATOM   818  C CD  . GLU A 1 119 ? -30.26550 -7.78568  -4.18446  1.000 54.38900  ? 118 GLU A CD  1 
ATOM   819  O OE1 . GLU A 1 119 ? -30.50619 -6.68505  -4.74267  1.000 43.53808  ? 118 GLU A OE1 1 
ATOM   820  O OE2 . GLU A 1 119 ? -29.89614 -7.89989  -2.98104  1.000 61.92170  ? 118 GLU A OE2 1 
ATOM   821  N N   . PHE A 1 120 ? -31.69439 -10.94197 -8.35511  1.000 38.70054  ? 119 PHE A N   1 
ATOM   822  C CA  . PHE A 1 120 ? -32.58557 -12.09001 -8.46104  1.000 38.51419  ? 119 PHE A CA  1 
ATOM   823  C C   . PHE A 1 120 ? -31.98963 -13.21172 -9.30298  1.000 38.60468  ? 119 PHE A C   1 
ATOM   824  O O   . PHE A 1 120 ? -32.25966 -14.38129 -9.02547  1.000 37.76818  ? 119 PHE A O   1 
ATOM   825  C CB  . PHE A 1 120 ? -33.93249 -11.66106 -9.03091  1.000 37.71229  ? 119 PHE A CB  1 
ATOM   826  C CG  . PHE A 1 120 ? -34.82232 -12.80336 -9.36550  1.000 36.48358  ? 119 PHE A CG  1 
ATOM   827  C CD1 . PHE A 1 120 ? -35.54323 -13.44124 -8.37435  1.000 38.92932  ? 119 PHE A CD1 1 
ATOM   828  C CD2 . PHE A 1 120 ? -34.92274 -13.25861 -10.67309 1.000 39.64024  ? 119 PHE A CD2 1 
ATOM   829  C CE1 . PHE A 1 120 ? -36.36303 -14.51766 -8.68205  1.000 47.34927  ? 119 PHE A CE1 1 
ATOM   830  C CE2 . PHE A 1 120 ? -35.72732 -14.33646 -10.99901 1.000 38.95858  ? 119 PHE A CE2 1 
ATOM   831  C CZ  . PHE A 1 120 ? -36.45722 -14.96830 -10.00669 1.000 45.02444  ? 119 PHE A CZ  1 
ATOM   832  N N   . THR A 1 121 ? -31.20180 -12.89000 -10.33821 1.000 37.41686  ? 120 THR A N   1 
ATOM   833  C CA  . THR A 1 121 ? -30.56446 -13.93887 -11.13106 1.000 31.43077  ? 120 THR A CA  1 
ATOM   834  C C   . THR A 1 121 ? -29.57994 -14.72630 -10.28306 1.000 36.36393  ? 120 THR A C   1 
ATOM   835  O O   . THR A 1 121 ? -29.56709 -15.95917 -10.31368 1.000 38.18843  ? 120 THR A O   1 
ATOM   836  C CB  . THR A 1 121 ? -29.86358 -13.34032 -12.35721 1.000 39.84154  ? 120 THR A CB  1 
ATOM   837  O OG1 . THR A 1 121 ? -30.83077 -12.73163 -13.22097 1.000 40.73909  ? 120 THR A OG1 1 
ATOM   838  C CG2 . THR A 1 121 ? -29.09108 -14.41163 -13.14473 1.000 33.11441  ? 120 THR A CG2 1 
ATOM   839  N N   . ASN A 1 122 ? -28.75593 -14.02678 -9.49701  1.000 42.39064  ? 121 ASN A N   1 
ATOM   840  C CA  . ASN A 1 122 ? -27.86426 -14.71082 -8.56288  1.000 39.09287  ? 121 ASN A CA  1 
ATOM   841  C C   . ASN A 1 122 ? -28.64783 -15.57746 -7.58548  1.000 40.48245  ? 121 ASN A C   1 
ATOM   842  O O   . ASN A 1 122 ? -28.25732 -16.71720 -7.30536  1.000 45.60656  ? 121 ASN A O   1 
ATOM   843  C CB  . ASN A 1 122 ? -27.01809 -13.69501 -7.80345  1.000 37.74147  ? 121 ASN A CB  1 
ATOM   844  C CG  . ASN A 1 122 ? -26.06280 -12.96318 -8.69363  1.000 40.67855  ? 121 ASN A CG  1 
ATOM   845  O OD1 . ASN A 1 122 ? -25.82187 -13.38399 -9.82770  1.000 50.51234  ? 121 ASN A OD1 1 
ATOM   846  N ND2 . ASN A 1 122 ? -25.49372 -11.86669 -8.19155  1.000 39.42364  ? 121 ASN A ND2 1 
ATOM   847  N N   . THR A 1 123 ? -29.74557 -15.04617 -7.04195  1.000 37.02954  ? 122 THR A N   1 
ATOM   848  C CA  . THR A 1 123 ? -30.61975 -15.84903 -6.19482  1.000 38.80595  ? 122 THR A CA  1 
ATOM   849  C C   . THR A 1 123 ? -31.00084 -17.14453 -6.89741  1.000 38.15367  ? 122 THR A C   1 
ATOM   850  O O   . THR A 1 123 ? -30.94010 -18.22871 -6.30486  1.000 41.37743  ? 122 THR A O   1 
ATOM   851  C CB  . THR A 1 123 ? -31.88096 -15.05485 -5.81587  1.000 43.71863  ? 122 THR A CB  1 
ATOM   852  O OG1 . THR A 1 123 ? -31.53271 -13.81513 -5.17864  1.000 44.11498  ? 122 THR A OG1 1 
ATOM   853  C CG2 . THR A 1 123 ? -32.77335 -15.85317 -4.88837  1.000 34.07882  ? 122 THR A CG2 1 
ATOM   854  N N   . ALA A 1 124 ? -31.35997 -17.05484 -8.17912  1.000 31.29692  ? 123 ALA A N   1 
ATOM   855  C CA  . ALA A 1 124 ? -31.87117 -18.22086 -8.88424  1.000 32.23117  ? 123 ALA A CA  1 
ATOM   856  C C   . ALA A 1 124 ? -30.78409 -19.20253 -9.27874  1.000 37.23220  ? 123 ALA A C   1 
ATOM   857  O O   . ALA A 1 124 ? -31.08129 -20.38772 -9.46338  1.000 39.15054  ? 123 ALA A O   1 
ATOM   858  C CB  . ALA A 1 124 ? -32.63512 -17.81107 -10.13781 1.000 32.95059  ? 123 ALA A CB  1 
ATOM   859  N N   . SER A 1 125 ? -29.54046 -18.75281 -9.43444  1.000 39.47049  ? 124 SER A N   1 
ATOM   860  C CA  . SER A 1 125 ? -28.51992 -19.69202 -9.87546  1.000 40.02944  ? 124 SER A CA  1 
ATOM   861  C C   . SER A 1 125 ? -28.14480 -20.66156 -8.77859  1.000 42.06894  ? 124 SER A C   1 
ATOM   862  O O   . SER A 1 125 ? -27.56089 -21.70918 -9.07297  1.000 49.19326  ? 124 SER A O   1 
ATOM   863  C CB  . SER A 1 125 ? -27.28071 -18.96022 -10.35713 1.000 35.73217  ? 124 SER A CB  1 
ATOM   864  O OG  . SER A 1 125 ? -27.66331 -17.78321 -11.02473 1.000 43.22258  ? 124 SER A OG  1 
ATOM   865  N N   . ILE A 1 126 ? -28.47824 -20.34399 -7.52985  1.000 38.38448  ? 125 ILE A N   1 
ATOM   866  C CA  . ILE A 1 126 ? -28.11197 -21.22680 -6.43340  1.000 41.64900  ? 125 ILE A CA  1 
ATOM   867  C C   . ILE A 1 126 ? -28.74458 -22.58458 -6.62819  1.000 43.05858  ? 125 ILE A C   1 
ATOM   868  O O   . ILE A 1 126 ? -28.07828 -23.62025 -6.52379  1.000 51.38542  ? 125 ILE A O   1 
ATOM   869  C CB  . ILE A 1 126 ? -28.51039 -20.61016 -5.08708  1.000 41.18477  ? 125 ILE A CB  1 
ATOM   870  C CG1 . ILE A 1 126 ? -27.47117 -19.55874 -4.76766  1.000 42.46260  ? 125 ILE A CG1 1 
ATOM   871  C CG2 . ILE A 1 126 ? -28.65215 -21.68840 -4.05358  1.000 35.36370  ? 125 ILE A CG2 1 
ATOM   872  C CD1 . ILE A 1 126 ? -26.05408 -20.07622 -5.06479  1.000 43.56200  ? 125 ILE A CD1 1 
ATOM   873  N N   . SER A 1 127 ? -30.03347 -22.58790 -6.95245  1.000 38.35913  ? 126 SER A N   1 
ATOM   874  C CA  . SER A 1 127 ? -30.79184 -23.80917 -7.14427  1.000 39.77324  ? 126 SER A CA  1 
ATOM   875  C C   . SER A 1 127 ? -30.52944 -24.39486 -8.51758  1.000 44.92883  ? 126 SER A C   1 
ATOM   876  O O   . SER A 1 127 ? -30.25586 -25.59309 -8.65417  1.000 45.38486  ? 126 SER A O   1 
ATOM   877  C CB  . SER A 1 127 ? -32.28019 -23.50890 -6.98603  1.000 43.72017  ? 126 SER A CB  1 
ATOM   878  O OG  . SER A 1 127 ? -32.51226 -22.77943 -5.79830  1.000 52.49342  ? 126 SER A OG  1 
ATOM   879  N N   . MET A 1 128 ? -30.61156 -23.54914 -9.54509  1.000 46.50078  ? 127 MET A N   1 
ATOM   880  C CA  . MET A 1 128 ? -30.57583 -24.02855 -10.91816 1.000 41.06288  ? 127 MET A CA  1 
ATOM   881  C C   . MET A 1 128 ? -29.21139 -24.59055 -11.29261 1.000 46.40977  ? 127 MET A C   1 
ATOM   882  O O   . MET A 1 128 ? -29.10509 -25.72962 -11.76860 1.000 50.82622  ? 127 MET A O   1 
ATOM   883  C CB  . MET A 1 128 ? -30.96434 -22.90290 -11.84564 1.000 37.82832  ? 127 MET A CB  1 
ATOM   884  C CG  . MET A 1 128 ? -32.39358 -23.00444 -12.19161 1.000 47.25316  ? 127 MET A CG  1 
ATOM   885  S SD  . MET A 1 128 ? -33.06090 -21.46253 -12.75602 1.000 51.38813  ? 127 MET A SD  1 
ATOM   886  C CE  . MET A 1 128 ? -34.08716 -21.07831 -11.33501 1.000 41.60106  ? 127 MET A CE  1 
ATOM   887  N N   . ASP A 1 129 ? -28.15381 -23.81228 -11.08892 1.000 43.95315  ? 128 ASP A N   1 
ATOM   888  C CA  . ASP A 1 129 ? -26.83609 -24.22172 -11.53554 1.000 47.97592  ? 128 ASP A CA  1 
ATOM   889  C C   . ASP A 1 129 ? -26.09280 -24.99856 -10.48739 1.000 47.92938  ? 128 ASP A C   1 
ATOM   890  O O   . ASP A 1 129 ? -24.86150 -25.04838 -10.52874 1.000 53.37008  ? 128 ASP A O   1 
ATOM   891  C CB  . ASP A 1 129 ? -26.01986 -23.01255 -11.97146 1.000 48.45670  ? 128 ASP A CB  1 
ATOM   892  C CG  . ASP A 1 129 ? -26.67912 -22.25750 -13.09528 1.000 57.50660  ? 128 ASP A CG  1 
ATOM   893  O OD1 . ASP A 1 129 ? -27.24776 -22.91792 -14.01548 1.000 57.56288  ? 128 ASP A OD1 1 
ATOM   894  O OD2 . ASP A 1 129 ? -26.63833 -21.00640 -13.03984 1.000 60.12866  ? 128 ASP A OD2 1 
ATOM   895  N N   . ARG A 1 130 ? -26.80475 -25.60539 -9.55853  1.000 50.76728  ? 129 ARG A N   1 
ATOM   896  C CA  . ARG A 1 130 ? -26.17626 -26.48691 -8.58703  1.000 48.33454  ? 129 ARG A CA  1 
ATOM   897  C C   . ARG A 1 130 ? -25.65901 -27.74362 -9.27351  1.000 50.46059  ? 129 ARG A C   1 
ATOM   898  O O   . ARG A 1 130 ? -26.43940 -28.45970 -9.92199  1.000 55.13447  ? 129 ARG A O   1 
ATOM   899  C CB  . ARG A 1 130 ? -27.16058 -26.85522 -7.49016  1.000 45.07735  ? 129 ARG A CB  1 
ATOM   900  C CG  . ARG A 1 130 ? -26.66336 -27.95773 -6.58793  1.000 45.77994  ? 129 ARG A CG  1 
ATOM   901  C CD  . ARG A 1 130 ? -27.41524 -27.93341 -5.29168  1.000 44.14263  ? 129 ARG A CD  1 
ATOM   902  N NE  . ARG A 1 130 ? -26.69398 -27.19658 -4.25890  1.000 44.56641  ? 129 ARG A NE  1 
ATOM   903  C CZ  . ARG A 1 130 ? -27.07576 -27.13481 -2.98886  1.000 41.86099  ? 129 ARG A CZ  1 
ATOM   904  N NH1 . ARG A 1 130 ? -28.16696 -27.74986 -2.56431  1.000 37.60918  ? 129 ARG A NH1 1 
ATOM   905  N NH2 . ARG A 1 130 ? -26.33722 -26.45113 -2.11968  1.000 41.29538  ? 129 ARG A NH2 1 
ATOM   906  N N   . PRO A 1 131 ? -24.37405 -28.04827 -9.16413  1.000 47.67740  ? 130 PRO A N   1 
ATOM   907  C CA  . PRO A 1 131 ? -23.86820 -29.31378 -9.69889  1.000 45.96373  ? 130 PRO A CA  1 
ATOM   908  C C   . PRO A 1 131 ? -24.64551 -30.49159 -9.13573  1.000 53.10056  ? 130 PRO A C   1 
ATOM   909  O O   . PRO A 1 131 ? -25.06986 -30.47780 -7.97826  1.000 53.50415  ? 130 PRO A O   1 
ATOM   910  C CB  . PRO A 1 131 ? -22.41298 -29.33320 -9.23115  1.000 37.11012  ? 130 PRO A CB  1 
ATOM   911  C CG  . PRO A 1 131 ? -22.36568 -28.36317 -8.08796  1.000 48.09350  ? 130 PRO A CG  1 
ATOM   912  C CD  . PRO A 1 131 ? -23.33573 -27.29286 -8.44916  1.000 46.47404  ? 130 PRO A CD  1 
ATOM   913  N N   . ASP A 1 132 ? -24.83154 -31.51915 -9.97263  1.000 56.59985  ? 131 ASP A N   1 
ATOM   914  C CA  . ASP A 1 132 ? -25.57447 -32.70365 -9.54188  1.000 54.68490  ? 131 ASP A CA  1 
ATOM   915  C C   . ASP A 1 132 ? -24.86196 -33.43279 -8.40634  1.000 53.29171  ? 131 ASP A C   1 
ATOM   916  O O   . ASP A 1 132 ? -25.51505 -34.07244 -7.57373  1.000 48.26029  ? 131 ASP A O   1 
ATOM   917  C CB  . ASP A 1 132 ? -25.81073 -33.63966 -10.73210 1.000 56.15505  ? 131 ASP A CB  1 
ATOM   918  C CG  . ASP A 1 132 ? -27.01976 -33.22004 -11.57752 1.000 69.70439  ? 131 ASP A CG  1 
ATOM   919  O OD1 . ASP A 1 132 ? -27.83238 -32.39106 -11.08686 1.000 72.28882  ? 131 ASP A OD1 1 
ATOM   920  O OD2 . ASP A 1 132 ? -27.14868 -33.70003 -12.73134 1.000 65.37735  ? 131 ASP A OD2 1 
ATOM   921  N N   . THR A 1 133 ? -23.53076 -33.33124 -8.34073  1.000 57.58460  ? 132 THR A N   1 
ATOM   922  C CA  . THR A 1 133 ? -22.79367 -33.89171 -7.20987  1.000 56.24210  ? 132 THR A CA  1 
ATOM   923  C C   . THR A 1 133 ? -23.36148 -33.41924 -5.86903  1.000 53.21928  ? 132 THR A C   1 
ATOM   924  O O   . THR A 1 133 ? -23.67722 -34.23390 -4.99640  1.000 55.60769  ? 132 THR A O   1 
ATOM   925  C CB  . THR A 1 133 ? -21.29109 -33.55842 -7.32408  1.000 55.95761  ? 132 THR A CB  1 
ATOM   926  O OG1 . THR A 1 133 ? -20.68277 -33.56142 -6.01569  1.000 62.75791  ? 132 THR A OG1 1 
ATOM   927  C CG2 . THR A 1 133 ? -21.02612 -32.23899 -8.04167  1.000 40.06835  ? 132 THR A CG2 1 
ATOM   928  N N   . ARG A 1 134 ? -23.52448 -32.10854 -5.69668  1.000 54.05289  ? 133 ARG A N   1 
ATOM   929  C CA  . ARG A 1 134 ? -23.93692 -31.53490 -4.41987  1.000 43.67796  ? 133 ARG A CA  1 
ATOM   930  C C   . ARG A 1 134 ? -25.43491 -31.67570 -4.14147  1.000 49.22486  ? 133 ARG A C   1 
ATOM   931  O O   . ARG A 1 134 ? -25.92919 -31.03061 -3.20414  1.000 51.76574  ? 133 ARG A O   1 
ATOM   932  C CB  . ARG A 1 134 ? -23.53744 -30.06033 -4.35552  1.000 39.83865  ? 133 ARG A CB  1 
ATOM   933  C CG  . ARG A 1 134 ? -22.05185 -29.84285 -4.44784  1.000 46.69020  ? 133 ARG A CG  1 
ATOM   934  C CD  . ARG A 1 134 ? -21.70116 -28.50083 -3.89825  1.000 48.16359  ? 133 ARG A CD  1 
ATOM   935  N NE  . ARG A 1 134 ? -20.99353 -27.67111 -4.85614  1.000 46.86782  ? 133 ARG A NE  1 
ATOM   936  C CZ  . ARG A 1 134 ? -21.42590 -26.47955 -5.24323  1.000 60.69220  ? 133 ARG A CZ  1 
ATOM   937  N NH1 . ARG A 1 134 ? -22.61999 -26.02127 -4.87131  1.000 57.49656  ? 133 ARG A NH1 1 
ATOM   938  N NH2 . ARG A 1 134 ? -20.64675 -25.72791 -6.02019  1.000 59.51769  ? 133 ARG A NH2 1 
ATOM   939  N N   . ARG A 1 135 ? -26.16084 -32.49448 -4.91023  1.000 49.26539  ? 134 ARG A N   1 
ATOM   940  C CA  . ARG A 1 135 ? -27.57438 -32.75862 -4.65443  1.000 49.27593  ? 134 ARG A CA  1 
ATOM   941  C C   . ARG A 1 135 ? -27.71579 -34.00316 -3.78624  1.000 50.72988  ? 134 ARG A C   1 
ATOM   942  O O   . ARG A 1 135 ? -27.11870 -35.04607 -4.08256  1.000 53.58408  ? 134 ARG A O   1 
ATOM   943  C CB  . ARG A 1 135 ? -28.33969 -32.94712 -5.96325  1.000 46.29074  ? 134 ARG A CB  1 
ATOM   944  C CG  . ARG A 1 135 ? -28.14435 -31.82822 -6.94169  1.000 48.52655  ? 134 ARG A CG  1 
ATOM   945  C CD  . ARG A 1 135 ? -29.45544 -31.21960 -7.32268  1.000 48.36872  ? 134 ARG A CD  1 
ATOM   946  N NE  . ARG A 1 135 ? -29.28310 -30.20275 -8.35107  1.000 54.18643  ? 134 ARG A NE  1 
ATOM   947  C CZ  . ARG A 1 135 ? -29.83782 -28.99931 -8.30327  1.000 53.12649  ? 134 ARG A CZ  1 
ATOM   948  N NH1 . ARG A 1 135 ? -30.58583 -28.62324 -7.27267  1.000 41.63654  ? 134 ARG A NH1 1 
ATOM   949  N NH2 . ARG A 1 135 ? -29.64292 -28.15529 -9.31634  1.000 50.60692  ? 134 ARG A NH2 1 
ATOM   950  N N   . ILE A 1 136 ? -28.50223 -33.89655 -2.71956  1.000 45.32132  ? 135 ILE A N   1 
ATOM   951  C CA  . ILE A 1 136 ? -28.74133 -34.99974 -1.79827  1.000 45.27864  ? 135 ILE A CA  1 
ATOM   952  C C   . ILE A 1 136 ? -30.24049 -35.24835 -1.73645  1.000 46.60957  ? 135 ILE A C   1 
ATOM   953  O O   . ILE A 1 136 ? -31.00315 -34.30731 -1.50763  1.000 48.88766  ? 135 ILE A O   1 
ATOM   954  C CB  . ILE A 1 136 ? -28.19109 -34.72080 -0.38853  1.000 43.99633  ? 135 ILE A CB  1 
ATOM   955  C CG1 . ILE A 1 136 ? -26.76530 -34.17816 -0.49024  1.000 40.31985  ? 135 ILE A CG1 1 
ATOM   956  C CG2 . ILE A 1 136 ? -28.26119 -35.99202 0.46550   1.000 35.25181  ? 135 ILE A CG2 1 
ATOM   957  C CD1 . ILE A 1 136 ? -26.01096 -34.22939 0.80093   1.000 38.77831  ? 135 ILE A CD1 1 
ATOM   958  N N   . PRO A 1 137 ? -30.70316 -36.48534 -1.91543  1.000 44.16044  ? 136 PRO A N   1 
ATOM   959  C CA  . PRO A 1 137 ? -32.13755 -36.76344 -1.79412  1.000 41.45255  ? 136 PRO A CA  1 
ATOM   960  C C   . PRO A 1 137 ? -32.61515 -36.57536 -0.36736  1.000 43.73388  ? 136 PRO A C   1 
ATOM   961  O O   . PRO A 1 137 ? -31.86050 -36.74942 0.59606   1.000 43.70650  ? 136 PRO A O   1 
ATOM   962  C CB  . PRO A 1 137 ? -32.25769 -38.23294 -2.21743  1.000 42.82388  ? 136 PRO A CB  1 
ATOM   963  C CG  . PRO A 1 137 ? -30.93284 -38.60963 -2.75619  1.000 36.79367  ? 136 PRO A CG  1 
ATOM   964  C CD  . PRO A 1 137 ? -29.92705 -37.70792 -2.15117  1.000 37.61251  ? 136 PRO A CD  1 
ATOM   965  N N   . ALA A 1 138 ? -33.90099 -36.23878 -0.24683  1.000 43.55662  ? 137 ALA A N   1 
ATOM   966  C CA  . ALA A 1 138 ? -34.48025 -35.90825 1.05235   1.000 43.59551  ? 137 ALA A CA  1 
ATOM   967  C C   . ALA A 1 138 ? -34.23850 -37.01006 2.08176   1.000 42.21062  ? 137 ALA A C   1 
ATOM   968  O O   . ALA A 1 138 ? -33.84044 -36.73589 3.22031   1.000 36.02439  ? 137 ALA A O   1 
ATOM   969  C CB  . ALA A 1 138 ? -35.97806 -35.64090 0.89165   1.000 43.05669  ? 137 ALA A CB  1 
ATOM   970  N N   . ALA A 1 139 ? -34.47015 -38.26929 1.69637   1.000 41.04231  ? 138 ALA A N   1 
ATOM   971  C CA  . ALA A 1 139 ? -34.36978 -39.35275 2.66947   1.000 37.70193  ? 138 ALA A CA  1 
ATOM   972  C C   . ALA A 1 139 ? -32.94840 -39.52326 3.18909   1.000 39.14659  ? 138 ALA A C   1 
ATOM   973  O O   . ALA A 1 139 ? -32.76006 -39.85802 4.36601   1.000 43.70427  ? 138 ALA A O   1 
ATOM   974  C CB  . ALA A 1 139 ? -34.87432 -40.66436 2.07653   1.000 27.62608  ? 138 ALA A CB  1 
ATOM   975  N N   . GLU A 1 140 ? -31.93661 -39.30932 2.34712   1.000 38.36420  ? 139 GLU A N   1 
ATOM   976  C CA  . GLU A 1 140 ? -30.57322 -39.32958 2.86134   1.000 32.57990  ? 139 GLU A CA  1 
ATOM   977  C C   . GLU A 1 140 ? -30.34945 -38.18378 3.84656   1.000 34.87709  ? 139 GLU A C   1 
ATOM   978  O O   . GLU A 1 140 ? -29.74135 -38.37944 4.90540   1.000 39.48650  ? 139 GLU A O   1 
ATOM   979  C CB  . GLU A 1 140 ? -29.57316 -39.27421 1.70764   1.000 33.63866  ? 139 GLU A CB  1 
ATOM   980  N N   . LEU A 1 141 ? -30.86622 -36.98950 3.53144   1.000 33.62753  ? 140 LEU A N   1 
ATOM   981  C CA  . LEU A 1 141 ? -30.69355 -35.82858 4.40564   1.000 34.37807  ? 140 LEU A CA  1 
ATOM   982  C C   . LEU A 1 141 ? -31.25331 -36.07563 5.80319   1.000 39.46805  ? 140 LEU A C   1 
ATOM   983  O O   . LEU A 1 141 ? -30.63869 -35.68947 6.80345   1.000 41.57083  ? 140 LEU A O   1 
ATOM   984  C CB  . LEU A 1 141 ? -31.39432 -34.61980 3.80100   1.000 36.63023  ? 140 LEU A CB  1 
ATOM   985  C CG  . LEU A 1 141 ? -30.66265 -33.63752 2.91750   1.000 37.01383  ? 140 LEU A CG  1 
ATOM   986  C CD1 . LEU A 1 141 ? -31.60191 -32.45872 2.65286   1.000 36.48853  ? 140 LEU A CD1 1 
ATOM   987  C CD2 . LEU A 1 141 ? -29.38265 -33.21720 3.60081   1.000 33.44009  ? 140 LEU A CD2 1 
ATOM   988  N N   . ALA A 1 142 ? -32.43383 -36.69586 5.88936   1.000 36.90140  ? 141 ALA A N   1 
ATOM   989  C CA  . ALA A 1 142 ? -33.13037 -36.84684 7.15983   1.000 37.65065  ? 141 ALA A CA  1 
ATOM   990  C C   . ALA A 1 142 ? -32.27934 -37.52310 8.22214   1.000 38.75311  ? 141 ALA A C   1 
ATOM   991  O O   . ALA A 1 142 ? -32.55308 -37.36096 9.41867   1.000 44.89634  ? 141 ALA A O   1 
ATOM   992  C CB  . ALA A 1 142 ? -34.42441 -37.63348 6.94934   1.000 40.49263  ? 141 ALA A CB  1 
ATOM   993  N N   . VAL A 1 143 ? -31.26334 -38.27492 7.81286   1.000 36.79106  ? 142 VAL A N   1 
ATOM   994  C CA  . VAL A 1 143 ? -30.30444 -38.89205 8.71630   1.000 38.44906  ? 142 VAL A CA  1 
ATOM   995  C C   . VAL A 1 143 ? -28.91052 -38.31113 8.53661   1.000 35.22336  ? 142 VAL A C   1 
ATOM   996  O O   . VAL A 1 143 ? -27.93419 -38.89763 9.00046   1.000 38.86821  ? 142 VAL A O   1 
ATOM   997  C CB  . VAL A 1 143 ? -30.28896 -40.41976 8.54727   1.000 38.56106  ? 142 VAL A CB  1 
ATOM   998  C CG1 . VAL A 1 143 ? -31.67939 -40.95935 8.78011   1.000 39.69572  ? 142 VAL A CG1 1 
ATOM   999  C CG2 . VAL A 1 143 ? -29.79787 -40.80353 7.14542   1.000 32.53923  ? 142 VAL A CG2 1 
ATOM   1000 N N   . ALA A 1 144 ? -28.79083 -37.18244 7.85971   1.000 32.96693  ? 143 ALA A N   1 
ATOM   1001 C CA  . ALA A 1 144 ? -27.50702 -36.52547 7.74077   1.000 34.55586  ? 143 ALA A CA  1 
ATOM   1002 C C   . ALA A 1 144 ? -27.15830 -35.80001 9.03539   1.000 38.65583  ? 143 ALA A C   1 
ATOM   1003 O O   . ALA A 1 144 ? -28.02252 -35.49148 9.86514   1.000 40.12167  ? 143 ALA A O   1 
ATOM   1004 C CB  . ALA A 1 144 ? -27.52111 -35.52737 6.57750   1.000 39.25015  ? 143 ALA A CB  1 
ATOM   1005 N N   . ASP A 1 145 ? -25.87635 -35.49013 9.18457   1.000 35.87885  ? 144 ASP A N   1 
ATOM   1006 C CA  . ASP A 1 145 ? -25.51320 -34.64113 10.29203  1.000 35.13850  ? 144 ASP A CA  1 
ATOM   1007 C C   . ASP A 1 145 ? -25.92283 -33.18700 10.02810  1.000 39.21490  ? 144 ASP A C   1 
ATOM   1008 O O   . ASP A 1 145 ? -26.11936 -32.74962 8.88798   1.000 41.12370  ? 144 ASP A O   1 
ATOM   1009 C CB  . ASP A 1 145 ? -24.01452 -34.69792 10.57647  1.000 43.03757  ? 144 ASP A CB  1 
ATOM   1010 C CG  . ASP A 1 145 ? -23.22325 -33.67020 9.77962   1.000 52.97955  ? 144 ASP A CG  1 
ATOM   1011 O OD1 . ASP A 1 145 ? -23.44909 -33.52562 8.55324   1.000 58.57738  ? 144 ASP A OD1 1 
ATOM   1012 O OD2 . ASP A 1 145 ? -22.42703 -32.93090 10.41959  1.000 57.80776  ? 144 ASP A OD2 1 
ATOM   1013 N N   . PHE A 1 146 ? -26.04845 -32.44338 11.12670  1.000 42.36066  ? 145 PHE A N   1 
ATOM   1014 C CA  . PHE A 1 146 ? -26.24386 -30.99782 11.20243  1.000 37.19834  ? 145 PHE A CA  1 
ATOM   1015 C C   . PHE A 1 146 ? -25.77918 -30.17368 9.99169   1.000 38.52617  ? 145 PHE A C   1 
ATOM   1016 O O   . PHE A 1 146 ? -26.59403 -29.50532 9.34674   1.000 38.06744  ? 145 PHE A O   1 
ATOM   1017 C CB  . PHE A 1 146 ? -25.52762 -30.53855 12.46372  1.000 34.32122  ? 145 PHE A CB  1 
ATOM   1018 C CG  . PHE A 1 146 ? -25.76250 -29.13409 12.81430  1.000 30.47550  ? 145 PHE A CG  1 
ATOM   1019 C CD1 . PHE A 1 146 ? -26.96564 -28.53150 12.52639  1.000 32.80595  ? 145 PHE A CD1 1 
ATOM   1020 C CD2 . PHE A 1 146 ? -24.77465 -28.41199 13.45615  1.000 30.36664  ? 145 PHE A CD2 1 
ATOM   1021 C CE1 . PHE A 1 146 ? -27.17951 -27.21370 12.86130  1.000 38.75758  ? 145 PHE A CE1 1 
ATOM   1022 C CE2 . PHE A 1 146 ? -24.97717 -27.09574 13.79122  1.000 34.45123  ? 145 PHE A CE2 1 
ATOM   1023 C CZ  . PHE A 1 146 ? -26.18147 -26.49007 13.49506  1.000 35.21113  ? 145 PHE A CZ  1 
ATOM   1024 N N   . GLN A 1 147 ? -24.47979 -30.19955 9.67694   1.000 34.91329  ? 146 GLN A N   1 
ATOM   1025 C CA  . GLN A 1 147 ? -23.92879 -29.27240 8.69791   1.000 33.30816  ? 146 GLN A CA  1 
ATOM   1026 C C   . GLN A 1 147 ? -24.17811 -29.69599 7.25286   1.000 39.64182  ? 146 GLN A C   1 
ATOM   1027 O O   . GLN A 1 147 ? -24.12253 -28.83957 6.35775   1.000 35.21727  ? 146 GLN A O   1 
ATOM   1028 C CB  . GLN A 1 147 ? -22.42205 -29.09135 8.91469   1.000 36.42849  ? 146 GLN A CB  1 
ATOM   1029 C CG  . GLN A 1 147 ? -22.02392 -28.22934 10.10541  1.000 35.40212  ? 146 GLN A CG  1 
ATOM   1030 C CD  . GLN A 1 147 ? -22.41877 -26.76623 9.95544   1.000 37.41654  ? 146 GLN A CD  1 
ATOM   1031 O OE1 . GLN A 1 147 ? -22.02102 -26.08638 8.99769   1.000 36.57913  ? 146 GLN A OE1 1 
ATOM   1032 N NE2 . GLN A 1 147 ? -23.20537 -26.27168 10.91069  1.000 32.87411  ? 146 GLN A NE2 1 
ATOM   1033 N N   . THR A 1 148 ? -24.42280 -30.98474 6.98941   1.000 37.13900  ? 147 THR A N   1 
ATOM   1034 C CA  . THR A 1 148 ? -24.81432 -31.37378 5.63865   1.000 35.98234  ? 147 THR A CA  1 
ATOM   1035 C C   . THR A 1 148 ? -26.13321 -30.71317 5.25600   1.000 38.50078  ? 147 THR A C   1 
ATOM   1036 O O   . THR A 1 148 ? -26.24710 -30.09152 4.19398   1.000 40.47389  ? 147 THR A O   1 
ATOM   1037 C CB  . THR A 1 148 ? -24.93834 -32.88797 5.51223   1.000 34.31656  ? 147 THR A CB  1 
ATOM   1038 O OG1 . THR A 1 148 ? -23.76158 -33.51699 6.01539   1.000 37.85341  ? 147 THR A OG1 1 
ATOM   1039 C CG2 . THR A 1 148 ? -25.07006 -33.23100 4.05620   1.000 35.42279  ? 147 THR A CG2 1 
ATOM   1040 N N   . ILE A 1 149 ? -27.14860 -30.86120 6.11178   1.000 36.30681  ? 148 ILE A N   1 
ATOM   1041 C CA  . ILE A 1 149 ? -28.39147 -30.10937 5.97876   1.000 33.40253  ? 148 ILE A CA  1 
ATOM   1042 C C   . ILE A 1 149 ? -28.08700 -28.63786 5.71244   1.000 35.13468  ? 148 ILE A C   1 
ATOM   1043 O O   . ILE A 1 149 ? -28.70846 -27.99842 4.85745   1.000 31.85186  ? 148 ILE A O   1 
ATOM   1044 C CB  . ILE A 1 149 ? -29.23847 -30.30568 7.25798   1.000 35.91549  ? 148 ILE A CB  1 
ATOM   1045 C CG1 . ILE A 1 149 ? -29.61387 -31.76861 7.42173   1.000 30.85233  ? 148 ILE A CG1 1 
ATOM   1046 C CG2 . ILE A 1 149 ? -30.50523 -29.46482 7.26692   1.000 32.63356  ? 148 ILE A CG2 1 
ATOM   1047 C CD1 . ILE A 1 149 ? -30.00049 -32.11125 8.79459   1.000 32.03288  ? 148 ILE A CD1 1 
ATOM   1048 N N   . GLU A 1 150 ? -27.10248 -28.08554 6.42300   1.000 36.90776  ? 149 GLU A N   1 
ATOM   1049 C CA  . GLU A 1 150 ? -26.84903 -26.65181 6.34352   1.000 36.68589  ? 149 GLU A CA  1 
ATOM   1050 C C   . GLU A 1 150 ? -26.44974 -26.25311 4.93903   1.000 32.14350  ? 149 GLU A C   1 
ATOM   1051 O O   . GLU A 1 150 ? -26.95437 -25.26647 4.39950   1.000 35.58461  ? 149 GLU A O   1 
ATOM   1052 C CB  . GLU A 1 150 ? -25.76834 -26.24292 7.35280   1.000 37.51417  ? 149 GLU A CB  1 
ATOM   1053 C CG  . GLU A 1 150 ? -25.75624 -24.74369 7.74630   1.000 40.60391  ? 149 GLU A CG  1 
ATOM   1054 C CD  . GLU A 1 150 ? -27.02839 -24.27117 8.48388   1.000 50.16937  ? 149 GLU A CD  1 
ATOM   1055 O OE1 . GLU A 1 150 ? -27.66394 -25.12679 9.16082   1.000 56.52430  ? 149 GLU A OE1 1 
ATOM   1056 O OE2 . GLU A 1 150 ? -27.38625 -23.05373 8.38416   1.000 37.70155  ? 149 GLU A OE2 1 
ATOM   1057 N N   . LYS A 1 151 ? -25.55726 -27.02221 4.32262   1.000 31.81905  ? 150 LYS A N   1 
ATOM   1058 C CA  . LYS A 1 151 ? -25.09527 -26.67780 2.98538   1.000 32.10577  ? 150 LYS A CA  1 
ATOM   1059 C C   . LYS A 1 151 ? -26.07671 -27.13364 1.90437   1.000 34.54386  ? 150 LYS A C   1 
ATOM   1060 O O   . LYS A 1 151 ? -26.11380 -26.53921 0.82537   1.000 41.19139  ? 150 LYS A O   1 
ATOM   1061 C CB  . LYS A 1 151 ? -23.69568 -27.25866 2.74284   1.000 30.68502  ? 150 LYS A CB  1 
ATOM   1062 C CG  . LYS A 1 151 ? -23.64634 -28.77537 2.65346   1.000 28.58414  ? 150 LYS A CG  1 
ATOM   1063 C CD  . LYS A 1 151 ? -22.22838 -29.29796 2.76895   1.000 30.78949  ? 150 LYS A CD  1 
ATOM   1064 C CE  . LYS A 1 151 ? -22.14536 -30.81985 2.50057   1.000 36.76890  ? 150 LYS A CE  1 
ATOM   1065 N NZ  . LYS A 1 151 ? -21.36008 -31.62460 3.53178   1.000 51.62450  ? 150 LYS A NZ  1 
ATOM   1066 N N   . THR A 1 152 ? -26.90056 -28.14720 2.16192   1.000 29.55958  ? 151 THR A N   1 
ATOM   1067 C CA  . THR A 1 152 ? -27.86224 -28.56767 1.14763   1.000 29.97264  ? 151 THR A CA  1 
ATOM   1068 C C   . THR A 1 152 ? -29.04942 -27.61285 1.02939   1.000 32.46504  ? 151 THR A C   1 
ATOM   1069 O O   . THR A 1 152 ? -29.80225 -27.69946 0.05730   1.000 38.61574  ? 151 THR A O   1 
ATOM   1070 C CB  . THR A 1 152 ? -28.31053 -30.00427 1.45056   1.000 29.26524  ? 151 THR A CB  1 
ATOM   1071 O OG1 . THR A 1 152 ? -27.20376 -30.88139 1.24738   1.000 32.79630  ? 151 THR A OG1 1 
ATOM   1072 C CG2 . THR A 1 152 ? -29.42222 -30.47934 0.55751   1.000 28.63860  ? 151 THR A CG2 1 
ATOM   1073 N N   . MET A 1 153 ? -29.21962 -26.68204 1.95884   1.000 31.60301  ? 152 MET A N   1 
ATOM   1074 C CA  . MET A 1 153 ? -30.31149 -25.72222 1.86687   1.000 31.31456  ? 152 MET A CA  1 
ATOM   1075 C C   . MET A 1 153 ? -30.14992 -24.89448 0.59563   1.000 37.61898  ? 152 MET A C   1 
ATOM   1076 O O   . MET A 1 153 ? -29.02849 -24.53969 0.22508   1.000 39.43714  ? 152 MET A O   1 
ATOM   1077 C CB  . MET A 1 153 ? -30.26969 -24.80675 3.08945   1.000 35.42646  ? 152 MET A CB  1 
ATOM   1078 C CG  . MET A 1 153 ? -30.94242 -25.32137 4.37437   1.000 34.65304  ? 152 MET A CG  1 
ATOM   1079 S SD  . MET A 1 153 ? -32.37844 -26.41748 4.27038   1.000 42.04360  ? 152 MET A SD  1 
ATOM   1080 C CE  . MET A 1 153 ? -31.66957 -28.07333 4.25215   1.000 36.48038  ? 152 MET A CE  1 
ATOM   1081 N N   . THR A 1 154 ? -31.26628 -24.60261 -0.09892  1.000 38.41914  ? 153 THR A N   1 
ATOM   1082 C CA  . THR A 1 154 ? -31.26842 -23.60995 -1.18860  1.000 32.85270  ? 153 THR A CA  1 
ATOM   1083 C C   . THR A 1 154 ? -32.43139 -22.62399 -1.15766  1.000 39.63788  ? 153 THR A C   1 
ATOM   1084 O O   . THR A 1 154 ? -32.32622 -21.57477 -1.80569  1.000 42.29120  ? 153 THR A O   1 
ATOM   1085 C CB  . THR A 1 154 ? -31.29070 -24.27626 -2.57320  1.000 33.87408  ? 153 THR A CB  1 
ATOM   1086 O OG1 . THR A 1 154 ? -32.41752 -25.15339 -2.66294  1.000 37.17549  ? 153 THR A OG1 1 
ATOM   1087 C CG2 . THR A 1 154 ? -29.99997 -25.03445 -2.86926  1.000 36.65121  ? 153 THR A CG2 1 
ATOM   1088 N N   . GLU A 1 155 ? -33.52821 -22.92217 -0.44457  1.000 34.86771  ? 154 GLU A N   1 
ATOM   1089 C CA  . GLU A 1 155 ? -34.72766 -22.08348 -0.46921  1.000 30.94207  ? 154 GLU A CA  1 
ATOM   1090 C C   . GLU A 1 155 ? -34.45156 -20.64572 -0.01301  1.000 34.93853  ? 154 GLU A C   1 
ATOM   1091 O O   . GLU A 1 155 ? -35.06271 -19.70000 -0.52512  1.000 39.15408  ? 154 GLU A O   1 
ATOM   1092 C CB  . GLU A 1 155 ? -35.80873 -22.71470 0.41209   1.000 32.12624  ? 154 GLU A CB  1 
ATOM   1093 C CG  . GLU A 1 155 ? -36.50285 -23.94854 -0.14968  1.000 29.14379  ? 154 GLU A CG  1 
ATOM   1094 C CD  . GLU A 1 155 ? -35.60879 -25.19427 -0.22253  1.000 37.85795  ? 154 GLU A CD  1 
ATOM   1095 O OE1 . GLU A 1 155 ? -34.48818 -25.17277 0.34638   1.000 36.55089  ? 154 GLU A OE1 1 
ATOM   1096 O OE2 . GLU A 1 155 ? -36.03633 -26.20300 -0.85083  1.000 35.99451  ? 154 GLU A OE2 1 
ATOM   1097 N N   . GLY A 1 156 ? -33.56540 -20.45536 0.96429   1.000 30.84173  ? 155 GLY A N   1 
ATOM   1098 C CA  . GLY A 1 156 ? -33.39641 -19.10729 1.48899   1.000 32.63121  ? 155 GLY A CA  1 
ATOM   1099 C C   . GLY A 1 156 ? -34.63400 -18.62853 2.23612   1.000 39.21728  ? 155 GLY A C   1 
ATOM   1100 O O   . GLY A 1 156 ? -35.50789 -19.41826 2.62457   1.000 42.40574  ? 155 GLY A O   1 
ATOM   1101 N N   . HIS A 1 157 ? -34.70921 -17.30860 2.42754   1.000 40.23301  ? 156 HIS A N   1 
ATOM   1102 C CA  . HIS A 1 157 ? -35.85462 -16.67653 3.09850   1.000 40.81274  ? 156 HIS A CA  1 
ATOM   1103 C C   . HIS A 1 157 ? -37.17284 -17.02672 2.40908   1.000 41.30303  ? 156 HIS A C   1 
ATOM   1104 O O   . HIS A 1 157 ? -37.33741 -16.71967 1.22208   1.000 42.87827  ? 156 HIS A O   1 
ATOM   1105 C CB  . HIS A 1 157 ? -35.68273 -15.15725 3.11939   1.000 46.49386  ? 156 HIS A CB  1 
ATOM   1106 C CG  . HIS A 1 157 ? -36.50186 -14.47342 4.17168   1.000 58.78850  ? 156 HIS A CG  1 
ATOM   1107 N ND1 . HIS A 1 157 ? -37.87844 -14.55753 4.21827   1.000 58.81005  ? 156 HIS A ND1 1 
ATOM   1108 C CD2 . HIS A 1 157 ? -36.13891 -13.69882 5.22150   1.000 63.71824  ? 156 HIS A CD2 1 
ATOM   1109 C CE1 . HIS A 1 157 ? -38.32740 -13.86446 5.24989   1.000 54.19534  ? 156 HIS A CE1 1 
ATOM   1110 N NE2 . HIS A 1 157 ? -37.29237 -13.33278 5.87473   1.000 63.62915  ? 156 HIS A NE2 1 
ATOM   1111 N N   . PRO A 1 158 ? -38.13366 -17.64374 3.10086   1.000 43.28389  ? 157 PRO A N   1 
ATOM   1112 C CA  . PRO A 1 158 ? -39.37004 -18.07790 2.41337   1.000 44.30247  ? 157 PRO A CA  1 
ATOM   1113 C C   . PRO A 1 158 ? -40.22674 -16.95304 1.83772   1.000 47.10744  ? 157 PRO A C   1 
ATOM   1114 O O   . PRO A 1 158 ? -41.03054 -17.22523 0.92849   1.000 45.57800  ? 157 PRO A O   1 
ATOM   1115 C CB  . PRO A 1 158 ? -40.13480 -18.84950 3.49881   1.000 34.69973  ? 157 PRO A CB  1 
ATOM   1116 C CG  . PRO A 1 158 ? -39.41541 -18.57776 4.77058   1.000 38.77634  ? 157 PRO A CG  1 
ATOM   1117 C CD  . PRO A 1 158 ? -38.00340 -18.24785 4.43139   1.000 40.20049  ? 157 PRO A CD  1 
ATOM   1118 N N   . CYS A 1 159 ? -40.09122 -15.71434 2.32184   1.000 42.27234  ? 158 CYS A N   1 
ATOM   1119 C CA  . CYS A 1 159 ? -40.97104 -14.62984 1.90001   1.000 43.58222  ? 158 CYS A CA  1 
ATOM   1120 C C   . CYS A 1 159 ? -40.36090 -13.79571 0.78719   1.000 46.34475  ? 158 CYS A C   1 
ATOM   1121 O O   . CYS A 1 159 ? -41.01644 -13.53316 -0.22503  1.000 44.18034  ? 158 CYS A O   1 
ATOM   1122 C CB  . CYS A 1 159 ? -41.31612 -13.71454 3.08133   1.000 49.69948  ? 158 CYS A CB  1 
ATOM   1123 S SG  . CYS A 1 159 ? -42.22606 -14.47180 4.47470   1.000 56.74685  ? 158 CYS A SG  1 
ATOM   1124 N N   . LEU A 1 160 ? -39.11684 -13.36854 0.95701   1.000 44.06828  ? 159 LEU A N   1 
ATOM   1125 C CA  . LEU A 1 160 ? -38.50280 -12.47656 -0.01080  1.000 44.67451  ? 159 LEU A CA  1 
ATOM   1126 C C   . LEU A 1 160 ? -38.06809 -13.26097 -1.23534  1.000 43.64010  ? 159 LEU A C   1 
ATOM   1127 O O   . LEU A 1 160 ? -37.61714 -14.40217 -1.13008  1.000 40.56327  ? 159 LEU A O   1 
ATOM   1128 C CB  . LEU A 1 160 ? -37.30546 -11.76336 0.60610   1.000 46.09908  ? 159 LEU A CB  1 
ATOM   1129 C CG  . LEU A 1 160 ? -37.66161 -10.63346 1.55811   1.000 50.49120  ? 159 LEU A CG  1 
ATOM   1130 C CD1 . LEU A 1 160 ? -36.51021 -10.38538 2.50354   1.000 59.10334  ? 159 LEU A CD1 1 
ATOM   1131 C CD2 . LEU A 1 160 ? -38.00786 -9.39329  0.76802   1.000 51.10641  ? 159 LEU A CD2 1 
ATOM   1132 N N   . VAL A 1 161 ? -38.19086 -12.64531 -2.40379  1.000 47.96503  ? 160 VAL A N   1 
ATOM   1133 C CA  . VAL A 1 161 ? -37.86015 -13.35368 -3.63508  1.000 43.27736  ? 160 VAL A CA  1 
ATOM   1134 C C   . VAL A 1 161 ? -36.37475 -13.25358 -3.95664  1.000 42.43310  ? 160 VAL A C   1 
ATOM   1135 O O   . VAL A 1 161 ? -35.69935 -14.27402 -4.13569  1.000 39.24432  ? 160 VAL A O   1 
ATOM   1136 C CB  . VAL A 1 161 ? -38.74052 -12.83803 -4.78659  1.000 41.48228  ? 160 VAL A CB  1 
ATOM   1137 C CG1 . VAL A 1 161 ? -38.44266 -13.61508 -6.04884  1.000 42.75251  ? 160 VAL A CG1 1 
ATOM   1138 C CG2 . VAL A 1 161 ? -40.21164 -12.98823 -4.41322  1.000 34.91976  ? 160 VAL A CG2 1 
ATOM   1139 N N   . ALA A 1 162 ? -35.83631 -12.03207 -4.00469  1.000 43.75092  ? 161 ALA A N   1 
ATOM   1140 C CA  . ALA A 1 162 ? -34.42107 -11.81444 -4.32716  1.000 44.58081  ? 161 ALA A CA  1 
ATOM   1141 C C   . ALA A 1 162 ? -33.53812 -11.97561 -3.08256  1.000 49.62657  ? 161 ALA A C   1 
ATOM   1142 O O   . ALA A 1 162 ? -32.84461 -11.05426 -2.63655  1.000 49.57952  ? 161 ALA A O   1 
ATOM   1143 C CB  . ALA A 1 162 ? -34.24217 -10.44091 -4.95913  1.000 41.72290  ? 161 ALA A CB  1 
ATOM   1144 N N   . ASN A 1 163 ? -33.54251 -13.19575 -2.53869  1.000 44.04180  ? 162 ASN A N   1 
ATOM   1145 C CA  . ASN A 1 163 ? -33.08411 -13.41356 -1.17528  1.000 42.04683  ? 162 ASN A CA  1 
ATOM   1146 C C   . ASN A 1 163 ? -31.61630 -13.83286 -1.05752  1.000 43.07675  ? 162 ASN A C   1 
ATOM   1147 O O   . ASN A 1 163 ? -31.13947 -14.06176 0.05803   1.000 50.60920  ? 162 ASN A O   1 
ATOM   1148 C CB  . ASN A 1 163 ? -34.00351 -14.43584 -0.48595  1.000 38.67363  ? 162 ASN A CB  1 
ATOM   1149 C CG  . ASN A 1 163 ? -33.82523 -15.84694 -0.99524  1.000 38.43450  ? 162 ASN A CG  1 
ATOM   1150 O OD1 . ASN A 1 163 ? -32.84345 -16.16932 -1.65661  1.000 41.41759  ? 162 ASN A OD1 1 
ATOM   1151 N ND2 . ASN A 1 163 ? -34.76354 -16.72166 -0.64007  1.000 35.50213  ? 162 ASN A ND2 1 
ATOM   1152 N N   . ALA A 1 164 ? -30.88720 -13.94693 -2.16318  1.000 43.55838  ? 163 ALA A N   1 
ATOM   1153 C CA  . ALA A 1 164 ? -29.48009 -14.33999 -2.13061  1.000 41.95521  ? 163 ALA A CA  1 
ATOM   1154 C C   . ALA A 1 164 ? -28.72201 -13.56327 -3.20359  1.000 42.11033  ? 163 ALA A C   1 
ATOM   1155 O O   . ALA A 1 164 ? -28.18042 -14.11198 -4.15635  1.000 43.83605  ? 163 ALA A O   1 
ATOM   1156 C CB  . ALA A 1 164 ? -29.30574 -15.84562 -2.32342  1.000 34.61457  ? 163 ALA A CB  1 
ATOM   1157 N N   . GLY A 1 165 ? -28.69485 -12.24304 -3.06400  1.000 44.86363  ? 164 GLY A N   1 
ATOM   1158 C CA  . GLY A 1 165 ? -27.95232 -11.44731 -4.02164  1.000 46.87033  ? 164 GLY A CA  1 
ATOM   1159 C C   . GLY A 1 165 ? -26.45538 -11.66090 -3.91464  1.000 45.45301  ? 164 GLY A C   1 
ATOM   1160 O O   . GLY A 1 165 ? -25.76761 -11.77498 -4.93097  1.000 44.80780  ? 164 GLY A O   1 
ATOM   1161 N N   . ARG A 1 166 ? -25.93551 -11.72877 -2.68223  1.000 44.36687  ? 165 ARG A N   1 
ATOM   1162 C CA  . ARG A 1 166 ? -24.50538 -11.81189 -2.39135  1.000 37.57922  ? 165 ARG A CA  1 
ATOM   1163 C C   . ARG A 1 166 ? -23.71652 -10.88353 -3.29238  1.000 41.54138  ? 165 ARG A C   1 
ATOM   1164 O O   . ARG A 1 166 ? -22.60048 -11.20146 -3.72148  1.000 40.33095  ? 165 ARG A O   1 
ATOM   1165 C CB  . ARG A 1 166 ? -23.99900 -13.23644 -2.53034  1.000 38.61857  ? 165 ARG A CB  1 
ATOM   1166 C CG  . ARG A 1 166 ? -24.39525 -14.09847 -1.39232  1.000 35.68566  ? 165 ARG A CG  1 
ATOM   1167 C CD  . ARG A 1 166 ? -25.63307 -14.83560 -1.76233  1.000 36.36661  ? 165 ARG A CD  1 
ATOM   1168 N NE  . ARG A 1 166 ? -25.83219 -15.93692 -0.84652  1.000 33.32404  ? 165 ARG A NE  1 
ATOM   1169 C CZ  . ARG A 1 166 ? -25.62013 -17.19435 -1.18392  1.000 38.11168  ? 165 ARG A CZ  1 
ATOM   1170 N NH1 . ARG A 1 166 ? -25.20592 -17.52003 -2.40068  1.000 38.83571  ? 165 ARG A NH1 1 
ATOM   1171 N NH2 . ARG A 1 166 ? -25.80117 -18.14450 -0.27628  1.000 41.75451  ? 165 ARG A NH2 1 
ATOM   1172 N N   . LEU A 1 167 ? -24.32598 -9.74805  -3.59800  1.000 43.64170  ? 166 LEU A N   1 
ATOM   1173 C CA  . LEU A 1 167 ? -23.68523 -8.67542  -4.33599  1.000 42.34259  ? 166 LEU A CA  1 
ATOM   1174 C C   . LEU A 1 167 ? -22.35192 -8.30940  -3.68885  1.000 34.68771  ? 166 LEU A C   1 
ATOM   1175 O O   . LEU A 1 167 ? -22.30555 -7.94587  -2.51384  1.000 37.18621  ? 166 LEU A O   1 
ATOM   1176 C CB  . LEU A 1 167 ? -24.65491 -7.49691  -4.34244  1.000 41.59618  ? 166 LEU A CB  1 
ATOM   1177 C CG  . LEU A 1 167 ? -25.25560 -7.25098  -5.71224  1.000 41.70199  ? 166 LEU A CG  1 
ATOM   1178 C CD1 . LEU A 1 167 ? -26.04048 -8.49198  -6.10869  1.000 50.06554  ? 166 LEU A CD1 1 
ATOM   1179 C CD2 . LEU A 1 167 ? -26.22127 -6.10124  -5.58041  1.000 37.32519  ? 166 LEU A CD2 1 
ATOM   1180 N N   . GLY A 1 168 ? -21.26478 -8.45771  -4.44806  1.000 32.19199  ? 167 GLY A N   1 
ATOM   1181 C CA  . GLY A 1 168 ? -19.90549 -8.35347  -3.94350  1.000 28.62659  ? 167 GLY A CA  1 
ATOM   1182 C C   . GLY A 1 168 ? -19.07263 -9.60370  -4.16246  1.000 30.91353  ? 167 GLY A C   1 
ATOM   1183 O O   . GLY A 1 168 ? -17.84978 -9.50937  -4.30972  1.000 32.24528  ? 167 GLY A O   1 
ATOM   1184 N N   . PHE A 1 169 ? -19.70172 -10.77926 -4.17313  1.000 30.01092  ? 168 PHE A N   1 
ATOM   1185 C CA  . PHE A 1 169 ? -18.96035 -12.01389 -4.38126  1.000 31.61266  ? 168 PHE A CA  1 
ATOM   1186 C C   . PHE A 1 169 ? -18.77474 -12.24957 -5.86717  1.000 34.69542  ? 168 PHE A C   1 
ATOM   1187 O O   . PHE A 1 169 ? -19.73210 -12.16902 -6.64023  1.000 37.14236  ? 168 PHE A O   1 
ATOM   1188 C CB  . PHE A 1 169 ? -19.68798 -13.21350 -3.77564  1.000 34.25174  ? 168 PHE A CB  1 
ATOM   1189 C CG  . PHE A 1 169 ? -19.33615 -13.48605 -2.36001  1.000 33.02697  ? 168 PHE A CG  1 
ATOM   1190 C CD1 . PHE A 1 169 ? -18.43594 -12.68590 -1.68875  1.000 34.07776  ? 168 PHE A CD1 1 
ATOM   1191 C CD2 . PHE A 1 169 ? -19.93512 -14.53205 -1.68487  1.000 35.69500  ? 168 PHE A CD2 1 
ATOM   1192 C CE1 . PHE A 1 169 ? -18.13502 -12.93463 -0.36451  1.000 35.52566  ? 168 PHE A CE1 1 
ATOM   1193 C CE2 . PHE A 1 169 ? -19.63178 -14.79007 -0.36012  1.000 32.18821  ? 168 PHE A CE2 1 
ATOM   1194 C CZ  . PHE A 1 169 ? -18.73270 -13.99661 0.29417   1.000 33.06212  ? 168 PHE A CZ  1 
ATOM   1195 N N   . SER A 1 170 ? -17.54496 -12.54457 -6.26410  1.000 37.81856  ? 169 SER A N   1 
ATOM   1196 C CA  . SER A 1 170 ? -17.29103 -13.02711 -7.60332  1.000 34.91153  ? 169 SER A CA  1 
ATOM   1197 C C   . SER A 1 170 ? -17.82904 -14.44271 -7.71360  1.000 35.69195  ? 169 SER A C   1 
ATOM   1198 O O   . SER A 1 170 ? -18.33845 -15.01415 -6.75203  1.000 31.86839  ? 169 SER A O   1 
ATOM   1199 C CB  . SER A 1 170 ? -15.79589 -12.99550 -7.90670  1.000 41.75354  ? 169 SER A CB  1 
ATOM   1200 O OG  . SER A 1 170 ? -15.11880 -14.05167 -7.23151  1.000 39.08786  ? 169 SER A OG  1 
ATOM   1201 N N   . ALA A 1 171 ? -17.68495 -15.03617 -8.89849  1.000 39.56221  ? 170 ALA A N   1 
ATOM   1202 C CA  . ALA A 1 171 ? -18.14241 -16.40648 -9.06320  1.000 34.68060  ? 170 ALA A CA  1 
ATOM   1203 C C   . ALA A 1 171 ? -17.25392 -17.39237 -8.32377  1.000 38.12879  ? 170 ALA A C   1 
ATOM   1204 O O   . ALA A 1 171 ? -17.71996 -18.48180 -7.97868  1.000 37.83311  ? 170 ALA A O   1 
ATOM   1205 C CB  . ALA A 1 171 ? -18.22727 -16.76737 -10.53878 1.000 31.92912  ? 170 ALA A CB  1 
ATOM   1206 N N   . ASP A 1 172 ? -15.99590 -17.03430 -8.06163  1.000 39.01768  ? 171 ASP A N   1 
ATOM   1207 C CA  . ASP A 1 172 ? -15.17793 -17.86460 -7.18851  1.000 39.68682  ? 171 ASP A CA  1 
ATOM   1208 C C   . ASP A 1 172 ? -15.58380 -17.68466 -5.73881  1.000 38.84104  ? 171 ASP A C   1 
ATOM   1209 O O   . ASP A 1 172 ? -15.71497 -18.66368 -5.00232  1.000 36.27864  ? 171 ASP A O   1 
ATOM   1210 C CB  . ASP A 1 172 ? -13.69838 -17.53987 -7.34773  1.000 40.46421  ? 171 ASP A CB  1 
ATOM   1211 C CG  . ASP A 1 172 ? -13.26487 -17.54686 -8.77471  1.000 58.88842  ? 171 ASP A CG  1 
ATOM   1212 O OD1 . ASP A 1 172 ? -13.60420 -18.54829 -9.46210  1.000 68.13075  ? 171 ASP A OD1 1 
ATOM   1213 O OD2 . ASP A 1 172 ? -12.59686 -16.55863 -9.20195  1.000 55.06823  ? 171 ASP A OD2 1 
ATOM   1214 N N   . ASP A 1 173 ? -15.76710 -16.43829 -5.30408  1.000 37.47997  ? 172 ASP A N   1 
ATOM   1215 C CA  . ASP A 1 173 ? -16.14617 -16.23252 -3.91777  1.000 36.11988  ? 172 ASP A CA  1 
ATOM   1216 C C   . ASP A 1 173 ? -17.39809 -17.02621 -3.59408  1.000 38.84296  ? 172 ASP A C   1 
ATOM   1217 O O   . ASP A 1 173 ? -17.51042 -17.57098 -2.48923  1.000 45.00085  ? 172 ASP A O   1 
ATOM   1218 C CB  . ASP A 1 173 ? -16.33725 -14.74727 -3.62171  1.000 33.84280  ? 172 ASP A CB  1 
ATOM   1219 C CG  . ASP A 1 173 ? -15.07842 -13.94749 -3.88223  1.000 41.84655  ? 172 ASP A CG  1 
ATOM   1220 O OD1 . ASP A 1 173 ? -13.96605 -14.42938 -3.53101  1.000 39.52461  ? 172 ASP A OD1 1 
ATOM   1221 O OD2 . ASP A 1 173 ? -15.19664 -12.83901 -4.46297  1.000 47.94550  ? 172 ASP A OD2 1 
ATOM   1222 N N   . ILE A 1 174 ? -18.31558 -17.17418 -4.55912  1.000 34.48143  ? 173 ILE A N   1 
ATOM   1223 C CA  . ILE A 1 174 ? -19.44701 -18.06437 -4.32145  1.000 32.73823  ? 173 ILE A CA  1 
ATOM   1224 C C   . ILE A 1 174 ? -18.95040 -19.48382 -4.13236  1.000 36.50091  ? 173 ILE A C   1 
ATOM   1225 O O   . ILE A 1 174 ? -19.39013 -20.19684 -3.22441  1.000 41.71495  ? 173 ILE A O   1 
ATOM   1226 C CB  . ILE A 1 174 ? -20.48336 -17.99868 -5.45251  1.000 25.22861  ? 173 ILE A CB  1 
ATOM   1227 C CG1 . ILE A 1 174 ? -21.06832 -16.59890 -5.59555  1.000 27.06331  ? 173 ILE A CG1 1 
ATOM   1228 C CG2 . ILE A 1 174 ? -21.59493 -18.93052 -5.11791  1.000 22.99961  ? 173 ILE A CG2 1 
ATOM   1229 C CD1 . ILE A 1 174 ? -21.98792 -16.21897 -4.48443  1.000 32.60191  ? 173 ILE A CD1 1 
ATOM   1230 N N   . GLU A 1 175 ? -17.98817 -19.89974 -4.95284  1.000 37.76066  ? 174 GLU A N   1 
ATOM   1231 C CA  . GLU A 1 175 ? -17.50655 -21.27387 -4.88527  1.000 39.60170  ? 174 GLU A CA  1 
ATOM   1232 C C   . GLU A 1 175 ? -16.91533 -21.61999 -3.51942  1.000 39.76989  ? 174 GLU A C   1 
ATOM   1233 O O   . GLU A 1 175 ? -17.06586 -22.75732 -3.05885  1.000 39.51790  ? 174 GLU A O   1 
ATOM   1234 C CB  . GLU A 1 175 ? -16.47467 -21.51734 -5.98817  1.000 39.31027  ? 174 GLU A CB  1 
ATOM   1235 C CG  . GLU A 1 175 ? -15.98440 -22.94529 -6.08407  1.000 41.54329  ? 174 GLU A CG  1 
ATOM   1236 C CD  . GLU A 1 175 ? -17.12209 -23.94357 -5.95181  1.000 56.47870  ? 174 GLU A CD  1 
ATOM   1237 O OE1 . GLU A 1 175 ? -18.22284 -23.67235 -6.50710  1.000 57.86183  ? 174 GLU A OE1 1 
ATOM   1238 O OE2 . GLU A 1 175 ? -16.91903 -24.99300 -5.29004  1.000 57.25192  ? 174 GLU A OE2 1 
ATOM   1239 N N   . ARG A 1 176 ? -16.25113 -20.66637 -2.85673  1.000 37.33039  ? 175 ARG A N   1 
ATOM   1240 C CA  . ARG A 1 176 ? -15.51438 -20.94986 -1.63128  1.000 35.36211  ? 175 ARG A CA  1 
ATOM   1241 C C   . ARG A 1 176 ? -16.25369 -20.55180 -0.37796  1.000 38.29028  ? 175 ARG A C   1 
ATOM   1242 O O   . ARG A 1 176 ? -16.12385 -21.22334 0.65294   1.000 38.79066  ? 175 ARG A O   1 
ATOM   1243 C CB  . ARG A 1 176 ? -14.18037 -20.22508 -1.62678  1.000 33.76942  ? 175 ARG A CB  1 
ATOM   1244 C CG  . ARG A 1 176 ? -13.45607 -20.32564 -2.91896  1.000 38.73008  ? 175 ARG A CG  1 
ATOM   1245 C CD  . ARG A 1 176 ? -12.42053 -19.24233 -2.97154  1.000 44.04135  ? 175 ARG A CD  1 
ATOM   1246 N NE  . ARG A 1 176 ? -11.09997 -19.82133 -2.81157  1.000 45.09583  ? 175 ARG A NE  1 
ATOM   1247 C CZ  . ARG A 1 176 ? -10.36912 -20.29325 -3.80886  1.000 51.81373  ? 175 ARG A CZ  1 
ATOM   1248 N NH1 . ARG A 1 176 ? -10.77616 -20.19731 -5.06863  1.000 56.51771  ? 175 ARG A NH1 1 
ATOM   1249 N NH2 . ARG A 1 176 ? -9.20270  -20.87587 -3.53517  1.000 49.70255  ? 175 ARG A NH2 1 
ATOM   1250 N N   . TYR A 1 177 ? -17.03299 -19.49374 -0.44831  1.000 33.73238  ? 176 TYR A N   1 
ATOM   1251 C CA  . TYR A 1 177 ? -17.59504 -18.90873 0.74436   1.000 35.48528  ? 176 TYR A CA  1 
ATOM   1252 C C   . TYR A 1 177 ? -19.11577 -18.97377 0.79532   1.000 38.41265  ? 176 TYR A C   1 
ATOM   1253 O O   . TYR A 1 177 ? -19.71788 -18.50074 1.77331   1.000 38.86804  ? 176 TYR A O   1 
ATOM   1254 C CB  . TYR A 1 177 ? -17.11135 -17.46280 0.84345   1.000 35.88974  ? 176 TYR A CB  1 
ATOM   1255 C CG  . TYR A 1 177 ? -15.61135 -17.31916 0.70851   1.000 34.51788  ? 176 TYR A CG  1 
ATOM   1256 C CD1 . TYR A 1 177 ? -14.73447 -18.03761 1.52327   1.000 33.61743  ? 176 TYR A CD1 1 
ATOM   1257 C CD2 . TYR A 1 177 ? -15.07059 -16.45630 -0.22511  1.000 36.05405  ? 176 TYR A CD2 1 
ATOM   1258 C CE1 . TYR A 1 177 ? -13.36109 -17.88569 1.40024   1.000 32.55046  ? 176 TYR A CE1 1 
ATOM   1259 C CE2 . TYR A 1 177 ? -13.70641 -16.30566 -0.35430  1.000 34.37692  ? 176 TYR A CE2 1 
ATOM   1260 C CZ  . TYR A 1 177 ? -12.86569 -17.01473 0.45018   1.000 33.65961  ? 176 TYR A CZ  1 
ATOM   1261 O OH  . TYR A 1 177 ? -11.52921 -16.82189 0.29310   1.000 36.42114  ? 176 TYR A OH  1 
ATOM   1262 N N   . ALA A 1 178 ? -19.73429 -19.52705 -0.18253  1.000 38.70964  ? 177 ALA A N   1 
ATOM   1263 C CA  . ALA A 1 178 ? -21.16585 -19.50271 0.06613   1.000 42.69647  ? 177 ALA A CA  1 
ATOM   1264 C C   . ALA A 1 178 ? -21.61598 -20.78034 0.78240   1.000 46.04760  ? 177 ALA A C   1 
ATOM   1265 O O   . ALA A 1 178 ? -21.00024 -21.84677 0.61968   1.000 43.92732  ? 177 ALA A O   1 
ATOM   1266 C CB  . ALA A 1 178 ? -21.92550 -19.33868 -1.24514  1.000 33.67884  ? 177 ALA A CB  1 
ATOM   1267 N N   . PRO A 1 179 ? -22.67698 -20.68608 1.59607   1.000 38.59599  ? 178 PRO A N   1 
ATOM   1268 C CA  . PRO A 1 179 ? -23.13446 -21.87170 2.33409   1.000 33.66979  ? 178 PRO A CA  1 
ATOM   1269 C C   . PRO A 1 179 ? -23.42479 -23.05060 1.43027   1.000 39.62793  ? 178 PRO A C   1 
ATOM   1270 O O   . PRO A 1 179 ? -22.94794 -24.15986 1.69294   1.000 45.90569  ? 178 PRO A O   1 
ATOM   1271 C CB  . PRO A 1 179 ? -24.40525 -21.38293 3.04039   1.000 30.49814  ? 178 PRO A CB  1 
ATOM   1272 C CG  . PRO A 1 179 ? -24.39440 -19.94787 2.95189   1.000 34.16784  ? 178 PRO A CG  1 
ATOM   1273 C CD  . PRO A 1 179 ? -23.56411 -19.53357 1.79256   1.000 36.11073  ? 178 PRO A CD  1 
ATOM   1274 N N   . GLU A 1 180 ? -24.20009 -22.84027 0.36582   1.000 39.06731  ? 179 GLU A N   1 
ATOM   1275 C CA  . GLU A 1 180 ? -24.61648 -23.92892 -0.51194  1.000 37.84541  ? 179 GLU A CA  1 
ATOM   1276 C C   . GLU A 1 180 ? -23.45714 -24.56566 -1.25561  1.000 41.05584  ? 179 GLU A C   1 
ATOM   1277 O O   . GLU A 1 180 ? -23.62973 -25.65338 -1.81516  1.000 42.77672  ? 179 GLU A O   1 
ATOM   1278 C CB  . GLU A 1 180 ? -25.65567 -23.43448 -1.51250  1.000 35.69227  ? 179 GLU A CB  1 
ATOM   1279 C CG  . GLU A 1 180 ? -25.09836 -22.48561 -2.54007  1.000 42.52735  ? 179 GLU A CG  1 
ATOM   1280 C CD  . GLU A 1 180 ? -24.95555 -21.08230 -2.00314  1.000 45.62026  ? 179 GLU A CD  1 
ATOM   1281 O OE1 . GLU A 1 180 ? -25.29915 -20.83520 -0.82324  1.000 42.91065  ? 179 GLU A OE1 1 
ATOM   1282 O OE2 . GLU A 1 180 ? -24.49345 -20.21713 -2.76123  1.000 45.19634  ? 179 GLU A OE2 1 
ATOM   1283 N N   . SER A 1 181 ? -22.28791 -23.92328 -1.27327  1.000 44.18815  ? 180 SER A N   1 
ATOM   1284 C CA  . SER A 1 181 ? -21.09708 -24.58554 -1.79337  1.000 41.87678  ? 180 SER A CA  1 
ATOM   1285 C C   . SER A 1 181 ? -20.58363 -25.63285 -0.82020  1.000 44.03483  ? 180 SER A C   1 
ATOM   1286 O O   . SER A 1 181 ? -20.21153 -26.73287 -1.23386  1.000 52.08988  ? 180 SER A O   1 
ATOM   1287 C CB  . SER A 1 181 ? -20.01189 -23.55970 -2.08975  1.000 42.50253  ? 180 SER A CB  1 
ATOM   1288 O OG  . SER A 1 181 ? -20.30260 -22.90758 -3.30473  1.000 41.94198  ? 180 SER A OG  1 
ATOM   1289 N N   . GLY A 1 182 ? -20.57497 -25.32048 0.47659   1.000 45.06822  ? 181 GLY A N   1 
ATOM   1290 C CA  . GLY A 1 182 ? -20.11950 -26.26238 1.47870   1.000 40.17926  ? 181 GLY A CA  1 
ATOM   1291 C C   . GLY A 1 182 ? -18.63409 -26.21667 1.73333   1.000 41.99628  ? 181 GLY A C   1 
ATOM   1292 O O   . GLY A 1 182 ? -18.05314 -27.22361 2.16059   1.000 38.21039  ? 181 GLY A O   1 
ATOM   1293 N N   . GLY A 1 183 ? -17.99735 -25.07608 1.48083   1.000 42.70695  ? 182 GLY A N   1 
ATOM   1294 C CA  . GLY A 1 183 ? -16.56707 -24.98784 1.63757   1.000 38.02143  ? 182 GLY A CA  1 
ATOM   1295 C C   . GLY A 1 183 ? -16.14840 -25.16011 3.07933   1.000 44.25397  ? 182 GLY A C   1 
ATOM   1296 O O   . GLY A 1 183 ? -16.92367 -24.96334 4.01471   1.000 49.84299  ? 182 GLY A O   1 
ATOM   1297 N N   . ARG A 1 184 ? -14.89178 -25.54514 3.25176   1.000 44.25344  ? 183 ARG A N   1 
ATOM   1298 C CA  . ARG A 1 184 ? -14.27677 -25.73614 4.56149   1.000 38.27350  ? 183 ARG A CA  1 
ATOM   1299 C C   . ARG A 1 184 ? -12.96266 -24.95606 4.51563   1.000 42.58318  ? 183 ARG A C   1 
ATOM   1300 O O   . ARG A 1 184 ? -11.90964 -25.52734 4.21892   1.000 47.23300  ? 183 ARG A O   1 
ATOM   1301 C CB  . ARG A 1 184 ? -14.05499 -27.24025 4.87253   1.000 36.46099  ? 183 ARG A CB  1 
ATOM   1302 C CG  . ARG A 1 184 ? -15.15340 -27.92463 5.67928   1.000 43.36425  ? 183 ARG A CG  1 
ATOM   1303 C CD  . ARG A 1 184 ? -16.28598 -28.43307 4.81066   1.000 46.46730  ? 183 ARG A CD  1 
ATOM   1304 N NE  . ARG A 1 184 ? -17.50558 -28.75735 5.55303   1.000 50.00035  ? 183 ARG A NE  1 
ATOM   1305 C CZ  . ARG A 1 184 ? -18.09523 -29.95155 5.56021   1.000 49.83454  ? 183 ARG A CZ  1 
ATOM   1306 N NH1 . ARG A 1 184 ? -17.53505 -31.00414 4.98486   1.000 49.26754  ? 183 ARG A NH1 1 
ATOM   1307 N NH2 . ARG A 1 184 ? -19.29510 -30.08661 6.12809   1.000 38.88787  ? 183 ARG A NH2 1 
ATOM   1308 N N   . PHE A 1 185 ? -13.02190 -23.65136 4.78135   1.000 36.50057  ? 184 PHE A N   1 
ATOM   1309 C CA  . PHE A 1 185 ? -11.82589 -22.81662 4.79295   1.000 32.32826  ? 184 PHE A CA  1 
ATOM   1310 C C   . PHE A 1 185 ? -11.36756 -22.49550 6.21302   1.000 37.86657  ? 184 PHE A C   1 
ATOM   1311 O O   . PHE A 1 185 ? -12.02687 -22.82621 7.19903   1.000 41.96745  ? 184 PHE A O   1 
ATOM   1312 C CB  . PHE A 1 185 ? -12.05372 -21.52309 4.01175   1.000 29.60668  ? 184 PHE A CB  1 
ATOM   1313 C CG  . PHE A 1 185 ? -13.26449 -20.76947 4.41771   1.000 31.55585  ? 184 PHE A CG  1 
ATOM   1314 C CD1 . PHE A 1 185 ? -14.50256 -21.10169 3.89983   1.000 33.30242  ? 184 PHE A CD1 1 
ATOM   1315 C CD2 . PHE A 1 185 ? -13.16362 -19.70053 5.28826   1.000 34.18646  ? 184 PHE A CD2 1 
ATOM   1316 C CE1 . PHE A 1 185 ? -15.62162 -20.41076 4.26675   1.000 33.85030  ? 184 PHE A CE1 1 
ATOM   1317 C CE2 . PHE A 1 185 ? -14.28440 -18.99337 5.66368   1.000 33.70648  ? 184 PHE A CE2 1 
ATOM   1318 C CZ  . PHE A 1 185 ? -15.51728 -19.35099 5.15517   1.000 36.48633  ? 184 PHE A CZ  1 
ATOM   1319 N N   . ALA A 1 186 ? -10.19384 -21.86711 6.30087   1.000 39.48134  ? 185 ALA A N   1 
ATOM   1320 C CA  . ALA A 1 186 ? -9.61512  -21.36343 7.53946   1.000 34.62387  ? 185 ALA A CA  1 
ATOM   1321 C C   . ALA A 1 186 ? -9.92050  -19.87901 7.68685   1.000 35.06553  ? 185 ALA A C   1 
ATOM   1322 O O   . ALA A 1 186 ? -10.33910 -19.21830 6.73967   1.000 36.54454  ? 185 ALA A O   1 
ATOM   1323 C CB  . ALA A 1 186 ? -8.10368  -21.58358 7.56330   1.000 30.98072  ? 185 ALA A CB  1 
ATOM   1324 N N   . LEU A 1 187 ? -9.73634  -19.35793 8.89345   1.000 37.69158  ? 186 LEU A N   1 
ATOM   1325 C CA  . LEU A 1 187 ? -9.89856  -17.93150 9.11820   1.000 34.94228  ? 186 LEU A CA  1 
ATOM   1326 C C   . LEU A 1 187 ? -8.52281  -17.30315 9.16838   1.000 41.60899  ? 186 LEU A C   1 
ATOM   1327 O O   . LEU A 1 187 ? -7.59489  -17.88775 9.73136   1.000 47.25405  ? 186 LEU A O   1 
ATOM   1328 C CB  . LEU A 1 187 ? -10.66095 -17.64879 10.41054  1.000 30.50891  ? 186 LEU A CB  1 
ATOM   1329 C CG  . LEU A 1 187 ? -12.10500 -18.16094 10.40801  1.000 36.09710  ? 186 LEU A CG  1 
ATOM   1330 C CD1 . LEU A 1 187 ? -12.86918 -17.69481 11.62524  1.000 32.89453  ? 186 LEU A CD1 1 
ATOM   1331 C CD2 . LEU A 1 187 ? -12.83041 -17.70845 9.15092   1.000 36.05196  ? 186 LEU A CD2 1 
ATOM   1332 N N   . GLU A 1 188 ? -8.37210  -16.13902 8.54596   1.000 39.42060  ? 187 GLU A N   1 
ATOM   1333 C CA  . GLU A 1 188 ? -7.14156  -15.37823 8.73867   1.000 44.71359  ? 187 GLU A CA  1 
ATOM   1334 C C   . GLU A 1 188 ? -7.22806  -14.62662 10.06176  1.000 37.94236  ? 187 GLU A C   1 
ATOM   1335 O O   . GLU A 1 188 ? -8.28183  -14.09428 10.41811  1.000 39.27716  ? 187 GLU A O   1 
ATOM   1336 C CB  . GLU A 1 188 ? -6.89459  -14.38124 7.59709   1.000 41.61701  ? 187 GLU A CB  1 
ATOM   1337 C CG  . GLU A 1 188 ? -7.18990  -14.87623 6.19770   1.000 50.38463  ? 187 GLU A CG  1 
ATOM   1338 C CD  . GLU A 1 188 ? -6.05906  -15.71087 5.60373   1.000 62.07789  ? 187 GLU A CD  1 
ATOM   1339 O OE1 . GLU A 1 188 ? -5.05191  -15.91743 6.33755   1.000 53.34584  ? 187 GLU A OE1 1 
ATOM   1340 O OE2 . GLU A 1 188 ? -6.19151  -16.15103 4.41499   1.000 54.34031  ? 187 GLU A OE2 1 
ATOM   1341 N N   . TRP A 1 189 ? -6.12153  -14.57489 10.78922  1.000 38.00422  ? 188 TRP A N   1 
ATOM   1342 C CA  . TRP A 1 189 ? -6.07304  -13.84322 12.04901  1.000 46.08715  ? 188 TRP A CA  1 
ATOM   1343 C C   . TRP A 1 189 ? -5.16569  -12.62453 11.92101  1.000 43.51601  ? 188 TRP A C   1 
ATOM   1344 O O   . TRP A 1 189 ? -4.18449  -12.63564 11.17423  1.000 48.11179  ? 188 TRP A O   1 
ATOM   1345 C CB  . TRP A 1 189 ? -5.57933  -14.74046 13.18790  1.000 39.68027  ? 188 TRP A CB  1 
ATOM   1346 C CG  . TRP A 1 189 ? -6.59150  -15.72403 13.67908  1.000 38.98948  ? 188 TRP A CG  1 
ATOM   1347 C CD1 . TRP A 1 189 ? -6.92097  -16.92357 13.10966  1.000 38.18054  ? 188 TRP A CD1 1 
ATOM   1348 C CD2 . TRP A 1 189 ? -7.41272  -15.59667 14.84717  1.000 44.18834  ? 188 TRP A CD2 1 
ATOM   1349 N NE1 . TRP A 1 189 ? -7.89419  -17.55433 13.85625  1.000 37.65484  ? 188 TRP A NE1 1 
ATOM   1350 C CE2 . TRP A 1 189 ? -8.21157  -16.76135 14.92895  1.000 40.53428  ? 188 TRP A CE2 1 
ATOM   1351 C CE3 . TRP A 1 189 ? -7.54622  -14.61575 15.83953  1.000 42.07688  ? 188 TRP A CE3 1 
ATOM   1352 C CZ2 . TRP A 1 189 ? -9.13308  -16.96455 15.96073  1.000 33.39296  ? 188 TRP A CZ2 1 
ATOM   1353 C CZ3 . TRP A 1 189 ? -8.46252  -14.82054 16.85400  1.000 38.30148  ? 188 TRP A CZ3 1 
ATOM   1354 C CH2 . TRP A 1 189 ? -9.24597  -15.98629 16.90575  1.000 32.35617  ? 188 TRP A CH2 1 
ATOM   1355 N N   . VAL A 1 190 ? -5.50063  -11.55757 12.63893  1.000 38.97042  ? 189 VAL A N   1 
ATOM   1356 C CA  . VAL A 1 190 ? -4.62147  -10.39864 12.69749  1.000 44.89911  ? 189 VAL A CA  1 
ATOM   1357 C C   . VAL A 1 190 ? -4.47296  -9.93649  14.13638  1.000 43.09792  ? 189 VAL A C   1 
ATOM   1358 O O   . VAL A 1 190 ? -5.32030  -10.19712 14.99075  1.000 46.22588  ? 189 VAL A O   1 
ATOM   1359 C CB  . VAL A 1 190 ? -5.10296  -9.21511  11.82257  1.000 45.67745  ? 189 VAL A CB  1 
ATOM   1360 C CG1 . VAL A 1 190 ? -5.54442  -9.67635  10.47524  1.000 42.56418  ? 189 VAL A CG1 1 
ATOM   1361 C CG2 . VAL A 1 190 ? -6.23448  -8.46952  12.51618  1.000 49.43317  ? 189 VAL A CG2 1 
ATOM   1362 N N   . ALA A 1 191 ? -3.38219  -9.22275  14.38712  1.000 40.71640  ? 190 ALA A N   1 
ATOM   1363 C CA  . ALA A 1 191 ? -3.15332  -8.56604  15.66235  1.000 43.34493  ? 190 ALA A CA  1 
ATOM   1364 C C   . ALA A 1 191 ? -3.57243  -7.11256  15.53340  1.000 40.94605  ? 190 ALA A C   1 
ATOM   1365 O O   . ALA A 1 191 ? -3.10732  -6.41234  14.63264  1.000 46.54512  ? 190 ALA A O   1 
ATOM   1366 C CB  . ALA A 1 191 ? -1.68580  -8.67139  16.07869  1.000 42.71436  ? 190 ALA A CB  1 
ATOM   1367 N N   . VAL A 1 192 ? -4.45872  -6.66137  16.41271  1.000 42.20145  ? 191 VAL A N   1 
ATOM   1368 C CA  . VAL A 1 192 ? -4.87058  -5.26058  16.44377  1.000 47.70009  ? 191 VAL A CA  1 
ATOM   1369 C C   . VAL A 1 192 ? -4.44527  -4.63212  17.76934  1.000 52.58948  ? 191 VAL A C   1 
ATOM   1370 O O   . VAL A 1 192 ? -4.62306  -5.23151  18.84023  1.000 50.07520  ? 191 VAL A O   1 
ATOM   1371 C CB  . VAL A 1 192 ? -6.38364  -5.10643  16.22201  1.000 48.73287  ? 191 VAL A CB  1 
ATOM   1372 C CG1 . VAL A 1 192 ? -6.71804  -5.35128  14.74901  1.000 47.83191  ? 191 VAL A CG1 1 
ATOM   1373 C CG2 . VAL A 1 192 ? -7.15399  -6.05680  17.12023  1.000 44.51416  ? 191 VAL A CG2 1 
ATOM   1374 N N   . LEU A 1 193 ? -3.87353  -3.42886  17.68176  1.000 48.24444  ? 192 LEU A N   1 
ATOM   1375 C CA  . LEU A 1 193 ? -3.43083  -2.66404  18.84323  1.000 48.71753  ? 192 LEU A CA  1 
ATOM   1376 C C   . LEU A 1 193 ? -4.54728  -2.49682  19.86732  1.000 50.30090  ? 192 LEU A C   1 
ATOM   1377 O O   . LEU A 1 193 ? -5.64537  -2.05308  19.53178  1.000 55.09585  ? 192 LEU A O   1 
ATOM   1378 C CB  . LEU A 1 193 ? -2.96459  -1.28816  18.37891  1.000 48.12841  ? 192 LEU A CB  1 
ATOM   1379 C CG  . LEU A 1 193 ? -1.47480  -1.04354  18.21869  1.000 46.07811  ? 192 LEU A CG  1 
ATOM   1380 C CD1 . LEU A 1 193 ? -1.28591  0.45160   18.26314  1.000 46.10209  ? 192 LEU A CD1 1 
ATOM   1381 C CD2 . LEU A 1 193 ? -0.66721  -1.74445  19.29491  1.000 42.46328  ? 192 LEU A CD2 1 
ATOM   1382 N N   . ARG A 1 194 ? -4.25991  -2.80589  21.13259  1.000 45.80861  ? 193 ARG A N   1 
ATOM   1383 C CA  . ARG A 1 194 ? -5.34874  -2.79612  22.10005  1.000 46.73431  ? 193 ARG A CA  1 
ATOM   1384 C C   . ARG A 1 194 ? -5.92107  -1.40133  22.28570  1.000 46.83442  ? 193 ARG A C   1 
ATOM   1385 O O   . ARG A 1 194 ? -7.08547  -1.26133  22.67151  1.000 48.84590  ? 193 ARG A O   1 
ATOM   1386 C CB  . ARG A 1 194 ? -4.88406  -3.37721  23.43629  1.000 48.78330  ? 193 ARG A CB  1 
ATOM   1387 C CG  . ARG A 1 194 ? -4.57934  -4.86891  23.39182  1.000 46.45238  ? 193 ARG A CG  1 
ATOM   1388 C CD  . ARG A 1 194 ? -4.24842  -5.42624  24.76035  1.000 47.51473  ? 193 ARG A CD  1 
ATOM   1389 N NE  . ARG A 1 194 ? -3.91698  -6.84628  24.72502  1.000 49.87035  ? 193 ARG A NE  1 
ATOM   1390 C CZ  . ARG A 1 194 ? -4.33037  -7.71827  25.63218  1.000 49.04267  ? 193 ARG A CZ  1 
ATOM   1391 N NH1 . ARG A 1 194 ? -5.07081  -7.33667  26.65981  1.000 49.46094  ? 193 ARG A NH1 1 
ATOM   1392 N NH2 . ARG A 1 194 ? -3.99705  -9.00198  25.50265  1.000 45.88404  ? 193 ARG A NH2 1 
ATOM   1393 N N   . VAL A 1 195 ? -5.14036  -0.36747  21.97755  1.000 48.78363  ? 194 VAL A N   1 
ATOM   1394 C CA  . VAL A 1 195 ? -5.60210  1.00344   22.14851  1.000 49.80193  ? 194 VAL A CA  1 
ATOM   1395 C C   . VAL A 1 195 ? -6.58604  1.42802   21.06998  1.000 54.31069  ? 194 VAL A C   1 
ATOM   1396 O O   . VAL A 1 195 ? -7.34683  2.38526   21.26217  1.000 51.03916  ? 194 VAL A O   1 
ATOM   1397 C CB  . VAL A 1 195 ? -4.38081  1.92173   22.16351  1.000 45.83404  ? 194 VAL A CB  1 
ATOM   1398 C CG1 . VAL A 1 195 ? -3.31781  1.27599   23.00710  1.000 48.05860  ? 194 VAL A CG1 1 
ATOM   1399 C CG2 . VAL A 1 195 ? -3.87626  2.12539   20.74687  1.000 48.13171  ? 194 VAL A CG2 1 
ATOM   1400 N N   . ASN A 1 196 ? -6.59089  0.74212   19.93301  1.000 56.48781  ? 195 ASN A N   1 
ATOM   1401 C CA  . ASN A 1 196 ? -7.52626  1.02676   18.85758  1.000 59.64418  ? 195 ASN A CA  1 
ATOM   1402 C C   . ASN A 1 196 ? -8.68688  0.03595   18.80871  1.000 57.40449  ? 195 ASN A C   1 
ATOM   1403 O O   . ASN A 1 196 ? -9.46101  0.05641   17.84593  1.000 59.86666  ? 195 ASN A O   1 
ATOM   1404 C CB  . ASN A 1 196 ? -6.79354  1.02903   17.51278  1.000 58.34941  ? 195 ASN A CB  1 
ATOM   1405 C CG  . ASN A 1 196 ? -5.95419  2.26617   17.31006  1.000 66.57094  ? 195 ASN A CG  1 
ATOM   1406 O OD1 . ASN A 1 196 ? -4.72943  2.21962   17.42447  1.000 65.83688  ? 195 ASN A OD1 1 
ATOM   1407 N ND2 . ASN A 1 196 ? -6.60969  3.38874   17.01052  1.000 74.46824  ? 195 ASN A ND2 1 
ATOM   1408 N N   . THR A 1 197 ? -8.83037  -0.82569  19.81540  1.000 51.53519  ? 196 THR A N   1 
ATOM   1409 C CA  . THR A 1 197 ? -9.77198  -1.93035  19.74621  1.000 49.83291  ? 196 THR A CA  1 
ATOM   1410 C C   . THR A 1 197 ? -10.65197 -1.98043  20.98856  1.000 49.98636  ? 196 THR A C   1 
ATOM   1411 O O   . THR A 1 197 ? -10.21850 -1.64899  22.09646  1.000 59.54957  ? 196 THR A O   1 
ATOM   1412 C CB  . THR A 1 197 ? -9.02603  -3.24893  19.57425  1.000 51.87548  ? 196 THR A CB  1 
ATOM   1413 O OG1 . THR A 1 197 ? -8.29642  -3.22918  18.33755  1.000 45.04298  ? 196 THR A OG1 1 
ATOM   1414 C CG2 . THR A 1 197 ? -9.99289  -4.40084  19.54872  1.000 50.87198  ? 196 THR A CG2 1 
ATOM   1415 N N   . ASP A 1 198 ? -11.90404 -2.38194  20.78558  1.000 44.53403  ? 197 ASP A N   1 
ATOM   1416 C CA  . ASP A 1 198 ? -12.85501 -2.62085  21.86329  1.000 40.16163  ? 197 ASP A CA  1 
ATOM   1417 C C   . ASP A 1 198 ? -13.11205 -4.11521  21.96564  1.000 41.69554  ? 197 ASP A C   1 
ATOM   1418 O O   . ASP A 1 198 ? -13.67677 -4.71830  21.05339  1.000 44.04025  ? 197 ASP A O   1 
ATOM   1419 C CB  . ASP A 1 198 ? -14.16293 -1.87757  21.62816  1.000 43.62603  ? 197 ASP A CB  1 
ATOM   1420 C CG  . ASP A 1 198 ? -13.99000 -0.39365  21.69710  1.000 56.57265  ? 197 ASP A CG  1 
ATOM   1421 O OD1 . ASP A 1 198 ? -13.01001 0.04171   22.34264  1.000 60.11043  ? 197 ASP A OD1 1 
ATOM   1422 O OD2 . ASP A 1 198 ? -14.83108 0.33165   21.12148  1.000 57.15898  ? 197 ASP A OD2 1 
ATOM   1423 N N   . PHE A 1 199 ? -12.70226 -4.71046  23.07085  1.000 43.66384  ? 198 PHE A N   1 
ATOM   1424 C CA  . PHE A 1 199 ? -13.07515 -6.07457  23.38169  1.000 36.51753  ? 198 PHE A CA  1 
ATOM   1425 C C   . PHE A 1 199 ? -14.16576 -6.08763  24.44885  1.000 33.37774  ? 198 PHE A C   1 
ATOM   1426 O O   . PHE A 1 199 ? -14.29116 -5.17028  25.25522  1.000 34.94813  ? 198 PHE A O   1 
ATOM   1427 C CB  . PHE A 1 199 ? -11.86875 -6.87377  23.84890  1.000 34.72774  ? 198 PHE A CB  1 
ATOM   1428 C CG  . PHE A 1 199 ? -12.19708 -8.29182  24.13538  1.000 42.20422  ? 198 PHE A CG  1 
ATOM   1429 C CD1 . PHE A 1 199 ? -12.30544 -9.20465  23.10901  1.000 44.51632  ? 198 PHE A CD1 1 
ATOM   1430 C CD2 . PHE A 1 199 ? -12.46334 -8.70876  25.42161  1.000 41.99894  ? 198 PHE A CD2 1 
ATOM   1431 C CE1 . PHE A 1 199 ? -12.63205 -10.51920 23.37123  1.000 45.25646  ? 198 PHE A CE1 1 
ATOM   1432 C CE2 . PHE A 1 199 ? -12.78514 -10.02657 25.69292  1.000 43.41013  ? 198 PHE A CE2 1 
ATOM   1433 C CZ  . PHE A 1 199 ? -12.87007 -10.92896 24.66778  1.000 46.92229  ? 198 PHE A CZ  1 
ATOM   1434 N N   . ALA A 1 200 ? -14.97993 -7.12611  24.42623  1.000 36.85626  ? 199 ALA A N   1 
ATOM   1435 C CA  . ALA A 1 200 ? -16.08827 -7.23244  25.35649  1.000 36.73660  ? 199 ALA A CA  1 
ATOM   1436 C C   . ALA A 1 200 ? -16.43575 -8.70660  25.50844  1.000 39.99240  ? 199 ALA A C   1 
ATOM   1437 O O   . ALA A 1 200 ? -16.04168 -9.54355  24.69018  1.000 42.10576  ? 199 ALA A O   1 
ATOM   1438 C CB  . ALA A 1 200 ? -17.29662 -6.40675  24.89716  1.000 30.18914  ? 199 ALA A CB  1 
ATOM   1439 N N   . ALA A 1 201 ? -17.14760 -9.02537  26.58658  1.000 37.85286  ? 200 ALA A N   1 
ATOM   1440 C CA  . ALA A 1 201 ? -17.49781 -10.40965 26.86600  1.000 40.44749  ? 200 ALA A CA  1 
ATOM   1441 C C   . ALA A 1 201 ? -18.65837 -10.41161 27.83127  1.000 33.06422  ? 200 ALA A C   1 
ATOM   1442 O O   . ALA A 1 201 ? -18.97699 -9.39479  28.43549  1.000 37.42489  ? 200 ALA A O   1 
ATOM   1443 C CB  . ALA A 1 201 ? -16.31958 -11.20325 27.43452  1.000 37.23327  ? 200 ALA A CB  1 
ATOM   1444 N N   . MET A 1 202 ? -19.31833 -11.54822 27.93135  1.000 39.34136  ? 201 MET A N   1 
ATOM   1445 C CA  . MET A 1 202 ? -20.32679 -11.64362 28.96196  1.000 44.39544  ? 201 MET A CA  1 
ATOM   1446 C C   . MET A 1 202 ? -19.63109 -12.04769 30.25685  1.000 48.40435  ? 201 MET A C   1 
ATOM   1447 O O   . MET A 1 202 ? -18.43913 -12.39051 30.26788  1.000 45.41854  ? 201 MET A O   1 
ATOM   1448 C CB  . MET A 1 202 ? -21.39126 -12.67412 28.60027  1.000 46.28056  ? 201 MET A CB  1 
ATOM   1449 C CG  . MET A 1 202 ? -22.04465 -12.49493 27.25341  1.000 45.77377  ? 201 MET A CG  1 
ATOM   1450 S SD  . MET A 1 202 ? -23.47637 -13.59592 27.18684  1.000 55.54419  ? 201 MET A SD  1 
ATOM   1451 C CE  . MET A 1 202 ? -22.69823 -15.14653 26.84581  1.000 47.72670  ? 201 MET A CE  1 
ATOM   1452 N N   . SER A 1 203 ? -20.38084 -12.01186 31.35693  1.000 48.95071  ? 202 SER A N   1 
ATOM   1453 C CA  . SER A 1 203 ? -19.84347 -12.48260 32.62537  1.000 49.05608  ? 202 SER A CA  1 
ATOM   1454 C C   . SER A 1 203 ? -19.40319 -13.93267 32.48909  1.000 45.89250  ? 202 SER A C   1 
ATOM   1455 O O   . SER A 1 203 ? -20.15261 -14.78085 31.99906  1.000 52.78900  ? 202 SER A O   1 
ATOM   1456 C CB  . SER A 1 203 ? -20.89124 -12.34755 33.72545  1.000 58.06941  ? 202 SER A CB  1 
ATOM   1457 O OG  . SER A 1 203 ? -21.13276 -10.98926 34.04372  1.000 60.60782  ? 202 SER A OG  1 
ATOM   1458 N N   . GLY A 1 204 ? -18.18359 -14.21858 32.90629  1.000 37.83163  ? 203 GLY A N   1 
ATOM   1459 C CA  . GLY A 1 204 ? -17.65021 -15.54539 32.80427  1.000 35.09371  ? 203 GLY A CA  1 
ATOM   1460 C C   . GLY A 1 204 ? -16.70812 -15.73446 31.64771  1.000 40.14394  ? 203 GLY A C   1 
ATOM   1461 O O   . GLY A 1 204 ? -15.91483 -16.68025 31.66127  1.000 47.07016  ? 203 GLY A O   1 
ATOM   1462 N N   . THR A 1 205 ? -16.76269 -14.85199 30.66039  1.000 38.27525  ? 204 THR A N   1 
ATOM   1463 C CA  . THR A 1 205 ? -15.86360 -14.89403 29.52404  1.000 39.64797  ? 204 THR A CA  1 
ATOM   1464 C C   . THR A 1 205 ? -14.82714 -13.78604 29.65522  1.000 42.46227  ? 204 THR A C   1 
ATOM   1465 O O   . THR A 1 205 ? -15.15526 -12.65498 30.03603  1.000 37.59252  ? 204 THR A O   1 
ATOM   1466 C CB  . THR A 1 205 ? -16.65308 -14.76552 28.22071  1.000 44.19272  ? 204 THR A CB  1 
ATOM   1467 O OG1 . THR A 1 205 ? -17.54303 -15.88563 28.11619  1.000 44.91508  ? 204 THR A OG1 1 
ATOM   1468 C CG2 . THR A 1 205 ? -15.71901 -14.73455 27.00302  1.000 39.12537  ? 204 THR A CG2 1 
ATOM   1469 N N   . GLU A 1 206 ? -13.56724 -14.13915 29.38422  1.000 44.64724  ? 205 GLU A N   1 
ATOM   1470 C CA  . GLU A 1 206 ? -12.45487 -13.20005 29.35503  1.000 45.25363  ? 205 GLU A CA  1 
ATOM   1471 C C   . GLU A 1 206 ? -11.63443 -13.44521 28.09264  1.000 45.92667  ? 205 GLU A C   1 
ATOM   1472 O O   . GLU A 1 206 ? -11.58444 -14.56792 27.58157  1.000 46.69228  ? 205 GLU A O   1 
ATOM   1473 C CB  . GLU A 1 206 ? -11.57635 -13.34313 30.61015  1.000 44.50943  ? 205 GLU A CB  1 
ATOM   1474 N N   . TYR A 1 207 ? -11.00274 -12.38675 27.57676  1.000 41.95643  ? 206 TYR A N   1 
ATOM   1475 C CA  . TYR A 1 207 ? -10.18407 -12.54556 26.37965  1.000 41.57890  ? 206 TYR A CA  1 
ATOM   1476 C C   . TYR A 1 207 ? -9.13692  -13.64347 26.55223  1.000 49.53353  ? 206 TYR A C   1 
ATOM   1477 O O   . TYR A 1 207 ? -8.97306  -14.50248 25.67615  1.000 48.60106  ? 206 TYR A O   1 
ATOM   1478 C CB  . TYR A 1 207 ? -9.49788  -11.23399 26.01184  1.000 40.14984  ? 206 TYR A CB  1 
ATOM   1479 C CG  . TYR A 1 207 ? -8.42731  -11.40238 24.93408  1.000 50.55972  ? 206 TYR A CG  1 
ATOM   1480 C CD1 . TYR A 1 207 ? -7.10315  -11.69541 25.27220  1.000 50.07291  ? 206 TYR A CD1 1 
ATOM   1481 C CD2 . TYR A 1 207 ? -8.73885  -11.26931 23.57590  1.000 45.17308  ? 206 TYR A CD2 1 
ATOM   1482 C CE1 . TYR A 1 207 ? -6.13464  -11.85882 24.29794  1.000 50.29955  ? 206 TYR A CE1 1 
ATOM   1483 C CE2 . TYR A 1 207 ? -7.76577  -11.42864 22.60072  1.000 43.04446  ? 206 TYR A CE2 1 
ATOM   1484 C CZ  . TYR A 1 207 ? -6.47368  -11.72533 22.97125  1.000 42.89589  ? 206 TYR A CZ  1 
ATOM   1485 O OH  . TYR A 1 207 ? -5.50085  -11.87531 22.02508  1.000 42.96207  ? 206 TYR A OH  1 
ATOM   1486 N N   . ASP A 1 208 ? -8.40056  -13.62070 27.67083  1.000 50.93656  ? 207 ASP A N   1 
ATOM   1487 C CA  . ASP A 1 208 ? -7.24280  -14.50346 27.79577  1.000 50.00477  ? 207 ASP A CA  1 
ATOM   1488 C C   . ASP A 1 208 ? -7.63966  -15.96393 27.76320  1.000 50.57094  ? 207 ASP A C   1 
ATOM   1489 O O   . ASP A 1 208 ? -6.85718  -16.80810 27.31394  1.000 55.28873  ? 207 ASP A O   1 
ATOM   1490 C CB  . ASP A 1 208 ? -6.48419  -14.21961 29.08155  1.000 50.71665  ? 207 ASP A CB  1 
ATOM   1491 C CG  . ASP A 1 208 ? -5.93705  -12.82841 29.12783  1.000 60.32112  ? 207 ASP A CG  1 
ATOM   1492 O OD1 . ASP A 1 208 ? -5.47883  -12.33216 28.07210  1.000 63.41613  ? 207 ASP A OD1 1 
ATOM   1493 O OD2 . ASP A 1 208 ? -5.96881  -12.23221 30.22544  1.000 71.04633  ? 207 ASP A OD2 1 
ATOM   1494 N N   . THR A 1 209 ? -8.83303  -16.28541 28.24595  1.000 46.03214  ? 208 THR A N   1 
ATOM   1495 C CA  . THR A 1 209 ? -9.25821  -17.67359 28.27670  1.000 48.71557  ? 208 THR A CA  1 
ATOM   1496 C C   . THR A 1 209 ? -10.01552 -18.06804 27.02314  1.000 45.63886  ? 208 THR A C   1 
ATOM   1497 O O   . THR A 1 209 ? -9.88236  -19.21068 26.56135  1.000 42.87676  ? 208 THR A O   1 
ATOM   1498 C CB  . THR A 1 209 ? -10.10537 -17.93783 29.52505  1.000 48.75382  ? 208 THR A CB  1 
ATOM   1499 O OG1 . THR A 1 209 ? -11.15555 -16.96734 29.62036  1.000 55.55746  ? 208 THR A OG1 1 
ATOM   1500 C CG2 . THR A 1 209 ? -9.23932  -17.85500 30.75761  1.000 42.41806  ? 208 THR A CG2 1 
ATOM   1501 N N   . LEU A 1 210 ? -10.78323 -17.13736 26.44852  1.000 45.99362  ? 209 LEU A N   1 
ATOM   1502 C CA  . LEU A 1 210 ? -11.41149 -17.38972 25.15381  1.000 43.31910  ? 209 LEU A CA  1 
ATOM   1503 C C   . LEU A 1 210 ? -10.36228 -17.70781 24.09389  1.000 46.28227  ? 209 LEU A C   1 
ATOM   1504 O O   . LEU A 1 210 ? -10.41618 -18.76573 23.45064  1.000 43.74150  ? 209 LEU A O   1 
ATOM   1505 C CB  . LEU A 1 210 ? -12.25755 -16.18858 24.74560  1.000 39.67582  ? 209 LEU A CB  1 
ATOM   1506 C CG  . LEU A 1 210 ? -12.96017 -16.17348 23.38632  1.000 41.58063  ? 209 LEU A CG  1 
ATOM   1507 C CD1 . LEU A 1 210 ? -14.23446 -17.00932 23.36923  1.000 33.05000  ? 209 LEU A CD1 1 
ATOM   1508 C CD2 . LEU A 1 210 ? -13.26282 -14.72154 23.02040  1.000 36.42911  ? 209 LEU A CD2 1 
ATOM   1509 N N   . ILE A 1 211 ? -9.36799  -16.82385 23.93470  1.000 40.50605  ? 210 ILE A N   1 
ATOM   1510 C CA  . ILE A 1 211 ? -8.32942  -17.05438 22.93937  1.000 37.93372  ? 210 ILE A CA  1 
ATOM   1511 C C   . ILE A 1 211 ? -7.57806  -18.35528 23.20204  1.000 45.52510  ? 210 ILE A C   1 
ATOM   1512 O O   . ILE A 1 211 ? -7.12531  -19.01465 22.25932  1.000 49.71364  ? 210 ILE A O   1 
ATOM   1513 C CB  . ILE A 1 211 ? -7.37552  -15.85095 22.86547  1.000 43.85622  ? 210 ILE A CB  1 
ATOM   1514 C CG1 . ILE A 1 211 ? -6.86241  -15.68879 21.43387  1.000 46.44208  ? 210 ILE A CG1 1 
ATOM   1515 C CG2 . ILE A 1 211 ? -6.20619  -16.03045 23.78443  1.000 43.14993  ? 210 ILE A CG2 1 
ATOM   1516 C CD1 . ILE A 1 211 ? -7.84773  -15.02111 20.51018  1.000 38.57371  ? 210 ILE A CD1 1 
ATOM   1517 N N   . ARG A 1 212 ? -7.44780  -18.77243 24.46224  1.000 50.32351  ? 211 ARG A N   1 
ATOM   1518 C CA  . ARG A 1 212 ? -6.79473  -20.05511 24.71782  1.000 50.25146  ? 211 ARG A CA  1 
ATOM   1519 C C   . ARG A 1 212 ? -7.64044  -21.22095 24.21006  1.000 50.35996  ? 211 ARG A C   1 
ATOM   1520 O O   . ARG A 1 212 ? -7.14399  -22.08320 23.47647  1.000 50.41584  ? 211 ARG A O   1 
ATOM   1521 C CB  . ARG A 1 212 ? -6.50478  -20.22875 26.20333  1.000 53.55509  ? 211 ARG A CB  1 
ATOM   1522 C CG  . ARG A 1 212 ? -5.05940  -20.03635 26.57472  1.000 61.04836  ? 211 ARG A CG  1 
ATOM   1523 C CD  . ARG A 1 212 ? -4.85921  -20.36513 28.05017  1.000 74.85296  ? 211 ARG A CD  1 
ATOM   1524 N NE  . ARG A 1 212 ? -4.90965  -19.16805 28.88578  1.000 72.31892  ? 211 ARG A NE  1 
ATOM   1525 C CZ  . ARG A 1 212 ? -5.64612  -19.05458 29.98417  1.000 70.42623  ? 211 ARG A CZ  1 
ATOM   1526 N NH1 . ARG A 1 212 ? -6.36367  -20.06915 30.44514  1.000 72.18962  ? 211 ARG A NH1 1 
ATOM   1527 N NH2 . ARG A 1 212 ? -5.66153  -17.89579 30.63819  1.000 69.46909  ? 211 ARG A NH2 1 
ATOM   1528 N N   . ASP A 1 213 ? -8.91930  -21.27769 24.60311  1.000 46.60461  ? 212 ASP A N   1 
ATOM   1529 C CA  . ASP A 1 213 ? -9.74713  -22.40650 24.19226  1.000 44.38801  ? 212 ASP A CA  1 
ATOM   1530 C C   . ASP A 1 213 ? -9.97500  -22.40547 22.70148  1.000 44.40905  ? 212 ASP A C   1 
ATOM   1531 O O   . ASP A 1 213 ? -10.25041 -23.45715 22.12116  1.000 49.29210  ? 212 ASP A O   1 
ATOM   1532 C CB  . ASP A 1 213 ? -11.11050 -22.37794 24.86625  1.000 49.81005  ? 212 ASP A CB  1 
ATOM   1533 C CG  . ASP A 1 213 ? -11.02720 -22.12084 26.33104  1.000 50.79056  ? 212 ASP A CG  1 
ATOM   1534 O OD1 . ASP A 1 213 ? -9.99289  -22.45063 26.94588  1.000 56.10131  ? 212 ASP A OD1 1 
ATOM   1535 O OD2 . ASP A 1 213 ? -12.00701 -21.57517 26.86281  1.000 53.81155  ? 212 ASP A OD2 1 
ATOM   1536 N N   . GLU A 1 214 ? -9.89851  -21.23765 22.07170  1.000 43.49203  ? 213 GLU A N   1 
ATOM   1537 C CA  . GLU A 1 214 ? -10.19091 -21.16645 20.65266  1.000 39.66414  ? 213 GLU A CA  1 
ATOM   1538 C C   . GLU A 1 214 ? -8.98639  -21.58391 19.81632  1.000 44.26992  ? 213 GLU A C   1 
ATOM   1539 O O   . GLU A 1 214 ? -9.11622  -22.38028 18.88578  1.000 46.84550  ? 213 GLU A O   1 
ATOM   1540 C CB  . GLU A 1 214 ? -10.65552 -19.76239 20.30310  1.000 34.85846  ? 213 GLU A CB  1 
ATOM   1541 C CG  . GLU A 1 214 ? -12.08480 -19.49746 20.73016  1.000 37.73278  ? 213 GLU A CG  1 
ATOM   1542 C CD  . GLU A 1 214 ? -13.06778 -20.48237 20.10834  1.000 43.44040  ? 213 GLU A CD  1 
ATOM   1543 O OE1 . GLU A 1 214 ? -13.22565 -20.47048 18.86447  1.000 50.49520  ? 213 GLU A OE1 1 
ATOM   1544 O OE2 . GLU A 1 214 ? -13.68990 -21.26996 20.85286  1.000 43.24283  ? 213 GLU A OE2 1 
ATOM   1545 N N   . LEU A 1 215 ? -7.79944  -21.09869 20.14462  1.000 41.81616  ? 214 LEU A N   1 
ATOM   1546 C CA  . LEU A 1 215 ? -6.68218  -21.29267 19.23894  1.000 43.35749  ? 214 LEU A CA  1 
ATOM   1547 C C   . LEU A 1 215 ? -5.65523  -22.29856 19.72963  1.000 50.09227  ? 214 LEU A C   1 
ATOM   1548 O O   . LEU A 1 215 ? -4.96792  -22.90746 18.90184  1.000 52.70532  ? 214 LEU A O   1 
ATOM   1549 C CB  . LEU A 1 215 ? -6.00304  -19.94646 18.95684  1.000 48.25363  ? 214 LEU A CB  1 
ATOM   1550 C CG  . LEU A 1 215 ? -6.83223  -19.03849 18.03715  1.000 37.65944  ? 214 LEU A CG  1 
ATOM   1551 C CD1 . LEU A 1 215 ? -6.31393  -17.61253 18.02899  1.000 39.85790  ? 214 LEU A CD1 1 
ATOM   1552 C CD2 . LEU A 1 215 ? -6.82796  -19.59378 16.65474  1.000 36.20498  ? 214 LEU A CD2 1 
ATOM   1553 N N   . GLY A 1 216 ? -5.53856  -22.50045 21.04197  1.000 47.67096  ? 215 GLY A N   1 
ATOM   1554 C CA  . GLY A 1 216 ? -4.62000  -23.47738 21.58601  1.000 41.11170  ? 215 GLY A CA  1 
ATOM   1555 C C   . GLY A 1 216 ? -3.21747  -22.92950 21.76983  1.000 47.38831  ? 215 GLY A C   1 
ATOM   1556 O O   . GLY A 1 216 ? -2.87053  -21.83565 21.32865  1.000 53.89694  ? 215 GLY A O   1 
ATOM   1557 N N   . ALA A 1 217 ? -2.38665  -23.72144 22.44191  1.000 55.87613  ? 216 ALA A N   1 
ATOM   1558 C CA  . ALA A 1 217 ? -1.05003  -23.25648 22.80081  1.000 53.91359  ? 216 ALA A CA  1 
ATOM   1559 C C   . ALA A 1 217 ? -0.18854  -23.02240 21.56614  1.000 56.78158  ? 216 ALA A C   1 
ATOM   1560 O O   . ALA A 1 217 ? 0.31689   -21.91182 21.35795  1.000 53.28281  ? 216 ALA A O   1 
ATOM   1561 C CB  . ALA A 1 217 ? -0.38051  -24.25805 23.73952  1.000 59.32780  ? 216 ALA A CB  1 
ATOM   1562 N N   . ASP A 1 218 ? -0.01641  -24.06146 20.73132  1.000 57.43418  ? 217 ASP A N   1 
ATOM   1563 C CA  . ASP A 1 218 ? 0.87386   -23.97024 19.56954  1.000 59.69703  ? 217 ASP A CA  1 
ATOM   1564 C C   . ASP A 1 218 ? 0.52163   -22.78173 18.67589  1.000 59.68090  ? 217 ASP A C   1 
ATOM   1565 O O   . ASP A 1 218 ? 1.39824   -21.99860 18.28637  1.000 56.13355  ? 217 ASP A O   1 
ATOM   1566 C CB  . ASP A 1 218 ? 0.83054   -25.26130 18.73872  1.000 70.11986  ? 217 ASP A CB  1 
ATOM   1567 C CG  . ASP A 1 218 ? 0.98403   -26.52274 19.57736  1.000 78.04550  ? 217 ASP A CG  1 
ATOM   1568 O OD1 . ASP A 1 218 ? 1.37640   -26.40912 20.75587  1.000 79.44700  ? 217 ASP A OD1 1 
ATOM   1569 O OD2 . ASP A 1 218 ? 0.73150   -27.63313 19.04264  1.000 76.14156  ? 217 ASP A OD2 1 
ATOM   1570 N N   . THR A 1 219 ? -0.76088  -22.64444 18.32278  1.000 58.57667  ? 218 THR A N   1 
ATOM   1571 C CA  . THR A 1 219 ? -1.16511  -21.55590 17.44130  1.000 50.31656  ? 218 THR A CA  1 
ATOM   1572 C C   . THR A 1 219 ? -0.86383  -20.20445 18.07689  1.000 48.38680  ? 218 THR A C   1 
ATOM   1573 O O   . THR A 1 219 ? -0.23397  -19.33835 17.45761  1.000 47.36588  ? 218 THR A O   1 
ATOM   1574 C CB  . THR A 1 219 ? -2.64649  -21.69865 17.08139  1.000 46.33578  ? 218 THR A CB  1 
ATOM   1575 O OG1 . THR A 1 219 ? -2.85617  -22.96606 16.44279  1.000 54.31629  ? 218 THR A OG1 1 
ATOM   1576 C CG2 . THR A 1 219 ? -3.07436  -20.60294 16.13490  1.000 46.29722  ? 218 THR A CG2 1 
ATOM   1577 N N   . LEU A 1 220 ? -1.27105  -20.02035 19.33220  1.000 50.43678  ? 219 LEU A N   1 
ATOM   1578 C CA  . LEU A 1 220 ? -1.04841  -18.73865 19.99033  1.000 48.52629  ? 219 LEU A CA  1 
ATOM   1579 C C   . LEU A 1 220 ? 0.43165   -18.40359 20.01444  1.000 48.86677  ? 219 LEU A C   1 
ATOM   1580 O O   . LEU A 1 220 ? 0.81972   -17.24354 19.85135  1.000 47.50184  ? 219 LEU A O   1 
ATOM   1581 C CB  . LEU A 1 220 ? -1.62875  -18.76355 21.40991  1.000 45.24140  ? 219 LEU A CB  1 
ATOM   1582 C CG  . LEU A 1 220 ? -3.05119  -18.21296 21.57667  1.000 46.56953  ? 219 LEU A CG  1 
ATOM   1583 C CD1 . LEU A 1 220 ? -3.53820  -18.36984 22.99841  1.000 50.24885  ? 219 LEU A CD1 1 
ATOM   1584 C CD2 . LEU A 1 220 ? -3.14771  -16.74285 21.15868  1.000 48.28566  ? 219 LEU A CD2 1 
ATOM   1585 N N   . ALA A 1 221 ? 1.27367   -19.41672 20.19853  1.000 50.01719  ? 220 ALA A N   1 
ATOM   1586 C CA  . ALA A 1 221 ? 2.70943   -19.19794 20.16093  1.000 45.27944  ? 220 ALA A CA  1 
ATOM   1587 C C   . ALA A 1 221 ? 3.15793   -18.80076 18.76324  1.000 51.36991  ? 220 ALA A C   1 
ATOM   1588 O O   . ALA A 1 221 ? 3.93132   -17.85145 18.59352  1.000 50.97519  ? 220 ALA A O   1 
ATOM   1589 C CB  . ALA A 1 221 ? 3.43228   -20.45641 20.62381  1.000 43.02007  ? 220 ALA A CB  1 
ATOM   1590 N N   . ARG A 1 222 ? 2.67289   -19.51077 17.74328  1.000 50.66301  ? 221 ARG A N   1 
ATOM   1591 C CA  . ARG A 1 222 ? 3.07073   -19.18248 16.38394  1.000 44.18085  ? 221 ARG A CA  1 
ATOM   1592 C C   . ARG A 1 222 ? 2.73176   -17.73610 16.05820  1.000 46.69275  ? 221 ARG A C   1 
ATOM   1593 O O   . ARG A 1 222 ? 3.60636   -16.96470 15.65839  1.000 49.52026  ? 221 ARG A O   1 
ATOM   1594 C CB  . ARG A 1 222 ? 2.41407   -20.13720 15.40023  1.000 45.17897  ? 221 ARG A CB  1 
ATOM   1595 C CG  . ARG A 1 222 ? 3.14715   -20.19491 14.08029  1.000 49.50736  ? 221 ARG A CG  1 
ATOM   1596 C CD  . ARG A 1 222 ? 2.21139   -19.85646 12.94901  1.000 49.21781  ? 221 ARG A CD  1 
ATOM   1597 N NE  . ARG A 1 222 ? 1.00959   -20.66708 13.03631  1.000 47.95919  ? 221 ARG A NE  1 
ATOM   1598 C CZ  . ARG A 1 222 ? -0.03319  -20.53952 12.23229  1.000 54.09150  ? 221 ARG A CZ  1 
ATOM   1599 N NH1 . ARG A 1 222 ? -0.04740  -19.63919 11.26411  1.000 56.12265  ? 221 ARG A NH1 1 
ATOM   1600 N NH2 . ARG A 1 222 ? -1.09202  -21.32718 12.41288  1.000 51.82926  ? 221 ARG A NH2 1 
ATOM   1601 N N   . PHE A 1 223 ? 1.47190   -17.33919 16.26412  1.000 47.23994  ? 222 PHE A N   1 
ATOM   1602 C CA  . PHE A 1 223 ? 1.09098   -15.94092 16.08188  1.000 44.93969  ? 222 PHE A CA  1 
ATOM   1603 C C   . PHE A 1 223 ? 2.04563   -15.01469 16.81080  1.000 50.01896  ? 222 PHE A C   1 
ATOM   1604 O O   . PHE A 1 223 ? 2.39054   -13.93974 16.30436  1.000 53.43231  ? 222 PHE A O   1 
ATOM   1605 C CB  . PHE A 1 223 ? -0.32308  -15.69211 16.59790  1.000 44.93381  ? 222 PHE A CB  1 
ATOM   1606 C CG  . PHE A 1 223 ? -1.40456  -16.30060 15.75766  1.000 46.25565  ? 222 PHE A CG  1 
ATOM   1607 C CD1 . PHE A 1 223 ? -1.10455  -17.06677 14.64750  1.000 46.88545  ? 222 PHE A CD1 1 
ATOM   1608 C CD2 . PHE A 1 223 ? -2.73229  -16.10466 16.08915  1.000 46.21225  ? 222 PHE A CD2 1 
ATOM   1609 C CE1 . PHE A 1 223 ? -2.10317  -17.63643 13.88969  1.000 45.54951  ? 222 PHE A CE1 1 
ATOM   1610 C CE2 . PHE A 1 223 ? -3.73435  -16.67050 15.33732  1.000 44.81726  ? 222 PHE A CE2 1 
ATOM   1611 C CZ  . PHE A 1 223 ? -3.41936  -17.43299 14.23342  1.000 46.19710  ? 222 PHE A CZ  1 
ATOM   1612 N N   . ASP A 1 224 ? 2.50026   -15.43505 17.99718  1.000 50.74228  ? 223 ASP A N   1 
ATOM   1613 C CA  . ASP A 1 224 ? 3.31537   -14.58319 18.86055  1.000 53.14354  ? 223 ASP A CA  1 
ATOM   1614 C C   . ASP A 1 224 ? 4.70964   -14.35608 18.28634  1.000 54.65656  ? 223 ASP A C   1 
ATOM   1615 O O   . ASP A 1 224 ? 5.25447   -13.24902 18.39264  1.000 52.46450  ? 223 ASP A O   1 
ATOM   1616 C CB  . ASP A 1 224 ? 3.41115   -15.20141 20.25718  1.000 54.55968  ? 223 ASP A CB  1 
ATOM   1617 C CG  . ASP A 1 224 ? 2.26254   -14.79326 21.16045  1.000 56.72511  ? 223 ASP A CG  1 
ATOM   1618 O OD1 . ASP A 1 224 ? 1.76851   -13.65712 21.01861  1.000 57.04784  ? 223 ASP A OD1 1 
ATOM   1619 O OD2 . ASP A 1 224 ? 1.84885   -15.61055 22.01101  1.000 63.32566  ? 223 ASP A OD2 1 
ATOM   1620 N N   . ARG A 1 225 ? 5.31079   -15.39297 17.69033  1.000 56.29368  ? 224 ARG A N   1 
ATOM   1621 C CA  . ARG A 1 225 ? 6.64095   -15.23477 17.10722  1.000 50.64827  ? 224 ARG A CA  1 
ATOM   1622 C C   . ARG A 1 225 ? 6.58939   -14.28965 15.91652  1.000 51.77542  ? 224 ARG A C   1 
ATOM   1623 O O   . ARG A 1 225 ? 7.38288   -13.34515 15.83682  1.000 56.17982  ? 224 ARG A O   1 
ATOM   1624 C CB  . ARG A 1 225 ? 7.22456   -16.59652 16.71817  1.000 39.21492  ? 224 ARG A CB  1 
ATOM   1625 N N   . VAL A 1 226 ? 5.64744   -14.52146 14.99205  1.000 51.30043  ? 225 VAL A N   1 
ATOM   1626 C CA  . VAL A 1 226 ? 5.27996   -13.55895 13.95765  1.000 49.39404  ? 225 VAL A CA  1 
ATOM   1627 C C   . VAL A 1 226 ? 5.39462   -12.15939 14.52941  1.000 55.07815  ? 225 VAL A C   1 
ATOM   1628 O O   . VAL A 1 226 ? 6.12262   -11.30721 14.01008  1.000 55.56857  ? 225 VAL A O   1 
ATOM   1629 C CB  . VAL A 1 226 ? 3.84596   -13.77995 13.44984  1.000 47.82744  ? 225 VAL A CB  1 
ATOM   1630 C CG1 . VAL A 1 226 ? 3.42714   -12.60789 12.59155  1.000 43.63366  ? 225 VAL A CG1 1 
ATOM   1631 C CG2 . VAL A 1 226 ? 3.72660   -15.07559 12.68313  1.000 46.26054  ? 225 VAL A CG2 1 
ATOM   1632 N N   . LEU A 1 227 ? 4.70766   -11.93875 15.64223  1.000 57.31924  ? 226 LEU A N   1 
ATOM   1633 C CA  . LEU A 1 227 ? 4.59232   -10.59418 16.17727  1.000 57.25201  ? 226 LEU A CA  1 
ATOM   1634 C C   . LEU A 1 227 ? 5.92776   -10.09999 16.74124  1.000 59.09214  ? 226 LEU A C   1 
ATOM   1635 O O   . LEU A 1 227 ? 6.29280   -8.93475  16.54388  1.000 59.91268  ? 226 LEU A O   1 
ATOM   1636 C CB  . LEU A 1 227 ? 3.49432   -10.58107 17.23715  1.000 55.15735  ? 226 LEU A CB  1 
ATOM   1637 C CG  . LEU A 1 227 ? 2.76946   -9.25915  17.40599  1.000 58.42963  ? 226 LEU A CG  1 
ATOM   1638 C CD1 . LEU A 1 227 ? 2.69455   -8.60024  16.04993  1.000 52.53958  ? 226 LEU A CD1 1 
ATOM   1639 C CD2 . LEU A 1 227 ? 1.38387   -9.48215  17.99590  1.000 56.62881  ? 226 LEU A CD2 1 
ATOM   1640 N N   . THR A 1 228 ? 6.67825   -10.96637 17.44071  1.000 57.61252  ? 227 THR A N   1 
ATOM   1641 C CA  . THR A 1 228 ? 7.93684   -10.51957 18.04413  1.000 59.54267  ? 227 THR A CA  1 
ATOM   1642 C C   . THR A 1 228 ? 9.05198   -10.38053 17.01238  1.000 62.22796  ? 227 THR A C   1 
ATOM   1643 O O   . THR A 1 228 ? 9.92862   -9.52183  17.16505  1.000 61.93170  ? 227 THR A O   1 
ATOM   1644 C CB  . THR A 1 228 ? 8.39989   -11.46931 19.16149  1.000 57.09834  ? 227 THR A CB  1 
ATOM   1645 O OG1 . THR A 1 228 ? 8.83467   -12.71311 18.60101  1.000 55.79155  ? 227 THR A OG1 1 
ATOM   1646 C CG2 . THR A 1 228 ? 7.28760   -11.72265 20.17208  1.000 49.29676  ? 227 THR A CG2 1 
ATOM   1647 N N   . GLY A 1 229 ? 9.04852   -11.21336 15.97029  1.000 61.39523  ? 228 GLY A N   1 
ATOM   1648 C CA  . GLY A 1 229 ? 9.97303   -11.00313 14.86803  1.000 60.89822  ? 228 GLY A CA  1 
ATOM   1649 C C   . GLY A 1 229 ? 9.73434   -9.69711  14.13245  1.000 56.13283  ? 228 GLY A C   1 
ATOM   1650 O O   . GLY A 1 229 ? 10.66922  -9.09368  13.60385  1.000 52.51752  ? 228 GLY A O   1 
ATOM   1651 N N   . ARG A 1 230 ? 8.49863   -9.25249  14.07040  1.000 60.63379  ? 229 ARG A N   1 
ATOM   1652 C CA  . ARG A 1 230 ? 8.32818   -7.87527  13.63098  1.000 64.39413  ? 229 ARG A CA  1 
ATOM   1653 C C   . ARG A 1 230 ? 8.74833   -6.86264  14.72878  1.000 67.07485  ? 229 ARG A C   1 
ATOM   1654 O O   . ARG A 1 230 ? 8.45070   -5.65987  14.60209  1.000 72.25768  ? 229 ARG A O   1 
ATOM   1655 C CB  . ARG A 1 230 ? 6.87766   -7.62150  13.20646  1.000 60.15465  ? 229 ARG A CB  1 
ATOM   1656 C CG  . ARG A 1 230 ? 6.55668   -7.94231  11.76644  1.000 61.74075  ? 229 ARG A CG  1 
ATOM   1657 C CD  . ARG A 1 230 ? 5.60339   -6.90419  11.16768  1.000 74.76150  ? 229 ARG A CD  1 
ATOM   1658 N NE  . ARG A 1 230 ? 6.10506   -5.53877  11.30393  1.000 79.51410  ? 229 ARG A NE  1 
ATOM   1659 C CZ  . ARG A 1 230 ? 5.41045   -4.44732  11.00414  1.000 77.42820  ? 229 ARG A CZ  1 
ATOM   1660 N NH1 . ARG A 1 230 ? 4.17068   -4.51968  10.53508  1.000 63.69668  ? 229 ARG A NH1 1 
ATOM   1661 N NH2 . ARG A 1 230 ? 5.96885   -3.25301  11.19181  1.000 76.00029  ? 229 ARG A NH2 1 
ATOM   1662 N N   . GLY A 1 231 ? 9.41378   -7.31238  15.79434  1.000 58.16987  ? 230 GLY A N   1 
ATOM   1663 C CA  . GLY A 1 231 ? 9.84290   -6.40464  16.83782  1.000 59.83955  ? 230 GLY A CA  1 
ATOM   1664 C C   . GLY A 1 231 ? 8.71736   -5.82347  17.65449  1.000 64.98660  ? 230 GLY A C   1 
ATOM   1665 O O   . GLY A 1 231 ? 8.89632   -4.78736  18.30345  1.000 60.21366  ? 230 GLY A O   1 
ATOM   1666 N N   . LEU A 1 232 ? 7.55629   -6.46394  17.64384  1.000 64.34218  ? 231 LEU A N   1 
ATOM   1667 C CA  . LEU A 1 232 ? 6.40140   -5.97361  18.36904  1.000 62.37701  ? 231 LEU A CA  1 
ATOM   1668 C C   . LEU A 1 232 ? 6.12742   -6.84179  19.58692  1.000 58.51869  ? 231 LEU A C   1 
ATOM   1669 O O   . LEU A 1 232 ? 6.39883   -8.04737  19.59109  1.000 56.91050  ? 231 LEU A O   1 
ATOM   1670 C CB  . LEU A 1 232 ? 5.17781   -5.91065  17.45649  1.000 57.08142  ? 231 LEU A CB  1 
ATOM   1671 C CG  . LEU A 1 232 ? 5.55910   -5.41439  16.06767  1.000 58.46407  ? 231 LEU A CG  1 
ATOM   1672 C CD1 . LEU A 1 232 ? 4.57471   -5.88975  15.01942  1.000 65.16567  ? 231 LEU A CD1 1 
ATOM   1673 C CD2 . LEU A 1 232 ? 5.65627   -3.90936  16.07536  1.000 56.00332  ? 231 LEU A CD2 1 
ATOM   1674 N N   . ASP A 1 233 ? 5.59590   -6.19764  20.62197  1.000 51.73475  ? 232 ASP A N   1 
ATOM   1675 C CA  . ASP A 1 233 ? 5.26814   -6.86799  21.86726  1.000 54.91759  ? 232 ASP A CA  1 
ATOM   1676 C C   . ASP A 1 233 ? 3.84346   -7.40058  21.80056  1.000 55.95670  ? 232 ASP A C   1 
ATOM   1677 O O   . ASP A 1 233 ? 2.90428   -6.60156  21.68243  1.000 56.35320  ? 232 ASP A O   1 
ATOM   1678 C CB  . ASP A 1 233 ? 5.41358   -5.90589  23.03001  1.000 53.55640  ? 232 ASP A CB  1 
ATOM   1679 C CG  . ASP A 1 233 ? 4.73888   -6.40008  24.28345  1.000 59.25989  ? 232 ASP A CG  1 
ATOM   1680 O OD1 . ASP A 1 233 ? 4.61194   -7.63705  24.44390  1.000 57.48644  ? 232 ASP A OD1 1 
ATOM   1681 O OD2 . ASP A 1 233 ? 4.33174   -5.54837  25.10962  1.000 62.04394  ? 232 ASP A OD2 1 
ATOM   1682 N N   . PRO A 1 234 ? 3.63085   -8.73130  21.90241  1.000 55.04219  ? 233 PRO A N   1 
ATOM   1683 C CA  . PRO A 1 234 ? 2.27080   -9.28780  21.81140  1.000 54.18386  ? 233 PRO A CA  1 
ATOM   1684 C C   . PRO A 1 234 ? 1.28889   -8.79792  22.86373  1.000 49.69435  ? 233 PRO A C   1 
ATOM   1685 O O   . PRO A 1 234 ? 0.10920   -9.15588  22.81782  1.000 51.44008  ? 233 PRO A O   1 
ATOM   1686 C CB  . PRO A 1 234 ? 2.51048   -10.79668 21.95019  1.000 48.98250  ? 233 PRO A CB  1 
ATOM   1687 C CG  . PRO A 1 234 ? 3.85293   -11.00820 21.35500  1.000 50.71358  ? 233 PRO A CG  1 
ATOM   1688 C CD  . PRO A 1 234 ? 4.65632   -9.77941  21.75793  1.000 54.13206  ? 233 PRO A CD  1 
ATOM   1689 N N   . ALA A 1 235 ? 1.73932   -7.97855  23.80516  1.000 54.12970  ? 234 ALA A N   1 
ATOM   1690 C CA  . ALA A 1 235 ? 0.84946   -7.51038  24.85632  1.000 50.30167  ? 234 ALA A CA  1 
ATOM   1691 C C   . ALA A 1 235 ? 0.12770   -6.22875  24.49548  1.000 49.01404  ? 234 ALA A C   1 
ATOM   1692 O O   . ALA A 1 235 ? -0.89330  -5.92436  25.11752  1.000 45.63745  ? 234 ALA A O   1 
ATOM   1693 C CB  . ALA A 1 235 ? 1.62136   -7.30275  26.15333  1.000 44.20092  ? 234 ALA A CB  1 
ATOM   1694 N N   . SER A 1 236 ? 0.63411   -5.47623  23.51691  1.000 49.44348  ? 235 SER A N   1 
ATOM   1695 C CA  . SER A 1 236 ? -0.03832  -4.28446  23.00344  1.000 52.95297  ? 235 SER A CA  1 
ATOM   1696 C C   . SER A 1 236 ? -1.23468  -4.60001  22.10671  1.000 53.42547  ? 235 SER A C   1 
ATOM   1697 O O   . SER A 1 236 ? -1.93318  -3.66203  21.69047  1.000 49.87636  ? 235 SER A O   1 
ATOM   1698 C CB  . SER A 1 236 ? 0.94621   -3.42414  22.20981  1.000 50.57543  ? 235 SER A CB  1 
ATOM   1699 O OG  . SER A 1 236 ? 2.05843   -3.05845  22.99770  1.000 55.37366  ? 235 SER A OG  1 
ATOM   1700 N N   . TYR A 1 237 ? -1.49099  -5.88470  21.82552  1.000 52.52242  ? 236 TYR A N   1 
ATOM   1701 C CA  . TYR A 1 237 ? -2.39359  -6.32135  20.76966  1.000 47.94956  ? 236 TYR A CA  1 
ATOM   1702 C C   . TYR A 1 237 ? -3.44591  -7.29102  21.29121  1.000 50.47551  ? 236 TYR A C   1 
ATOM   1703 O O   . TYR A 1 237 ? -3.25163  -7.98168  22.30140  1.000 48.21749  ? 236 TYR A O   1 
ATOM   1704 C CB  . TYR A 1 237 ? -1.63274  -7.02827  19.64794  1.000 47.50778  ? 236 TYR A CB  1 
ATOM   1705 C CG  . TYR A 1 237 ? -0.69015  -6.14366  18.87565  1.000 55.84993  ? 236 TYR A CG  1 
ATOM   1706 C CD1 . TYR A 1 237 ? -1.17559  -5.22934  17.94856  1.000 52.96093  ? 236 TYR A CD1 1 
ATOM   1707 C CD2 . TYR A 1 237 ? 0.68247   -6.22602  19.06852  1.000 51.19889  ? 236 TYR A CD2 1 
ATOM   1708 C CE1 . TYR A 1 237 ? -0.32914  -4.42131  17.24679  1.000 52.39249  ? 236 TYR A CE1 1 
ATOM   1709 C CE2 . TYR A 1 237 ? 1.53528   -5.42896  18.37437  1.000 51.91546  ? 236 TYR A CE2 1 
ATOM   1710 C CZ  . TYR A 1 237 ? 1.02768   -4.52144  17.46026  1.000 56.66200  ? 236 TYR A CZ  1 
ATOM   1711 O OH  . TYR A 1 237 ? 1.87904   -3.70923  16.74462  1.000 53.05881  ? 236 TYR A OH  1 
ATOM   1712 N N   . TYR A 1 238 ? -4.56739  -7.33787  20.56752  1.000 46.68717  ? 237 TYR A N   1 
ATOM   1713 C CA  . TYR A 1 238 ? -5.44644  -8.49957  20.54786  1.000 48.20935  ? 237 TYR A CA  1 
ATOM   1714 C C   . TYR A 1 238 ? -5.27065  -9.23570  19.22791  1.000 48.72942  ? 237 TYR A C   1 
ATOM   1715 O O   . TYR A 1 238 ? -4.96292  -8.62967  18.19507  1.000 44.77320  ? 237 TYR A O   1 
ATOM   1716 C CB  . TYR A 1 238 ? -6.92378  -8.13718  20.66291  1.000 44.03973  ? 237 TYR A CB  1 
ATOM   1717 C CG  . TYR A 1 238 ? -7.31555  -7.35456  21.87650  1.000 49.63458  ? 237 TYR A CG  1 
ATOM   1718 C CD1 . TYR A 1 238 ? -7.31513  -7.92706  23.14857  1.000 46.79942  ? 237 TYR A CD1 1 
ATOM   1719 C CD2 . TYR A 1 238 ? -7.71409  -6.03309  21.74857  1.000 46.73622  ? 237 TYR A CD2 1 
ATOM   1720 C CE1 . TYR A 1 238 ? -7.69439  -7.18695  24.24618  1.000 42.80699  ? 237 TYR A CE1 1 
ATOM   1721 C CE2 . TYR A 1 238 ? -8.09011  -5.29602  22.83660  1.000 47.40304  ? 237 TYR A CE2 1 
ATOM   1722 C CZ  . TYR A 1 238 ? -8.08221  -5.86783  24.07646  1.000 43.29734  ? 237 TYR A CZ  1 
ATOM   1723 O OH  . TYR A 1 238 ? -8.46944  -5.08563  25.13700  1.000 51.62820  ? 237 TYR A OH  1 
ATOM   1724 N N   . TYR A 1 239 ? -5.48475  -10.54358 19.26869  1.000 44.41603  ? 238 TYR A N   1 
ATOM   1725 C CA  . TYR A 1 239 ? -5.76260  -11.29762 18.06185  1.000 43.99785  ? 238 TYR A CA  1 
ATOM   1726 C C   . TYR A 1 239 ? -7.26335  -11.31838 17.80139  1.000 44.61051  ? 238 TYR A C   1 
ATOM   1727 O O   . TYR A 1 239 ? -8.06084  -11.40500 18.73605  1.000 47.50896  ? 238 TYR A O   1 
ATOM   1728 C CB  . TYR A 1 239 ? -5.24606  -12.71595 18.19496  1.000 43.09090  ? 238 TYR A CB  1 
ATOM   1729 C CG  . TYR A 1 239 ? -3.76779  -12.77117 18.35416  1.000 50.65481  ? 238 TYR A CG  1 
ATOM   1730 C CD1 . TYR A 1 239 ? -2.93080  -12.37944 17.31530  1.000 52.52590  ? 238 TYR A CD1 1 
ATOM   1731 C CD2 . TYR A 1 239 ? -3.19341  -13.24860 19.53067  1.000 49.43712  ? 238 TYR A CD2 1 
ATOM   1732 C CE1 . TYR A 1 239 ? -1.54929  -12.44378 17.45532  1.000 57.74994  ? 238 TYR A CE1 1 
ATOM   1733 C CE2 . TYR A 1 239 ? -1.81433  -13.33176 19.67807  1.000 46.85244  ? 238 TYR A CE2 1 
ATOM   1734 C CZ  . TYR A 1 239 ? -1.00031  -12.92731 18.64248  1.000 49.88445  ? 238 TYR A CZ  1 
ATOM   1735 O OH  . TYR A 1 239 ? 0.35803   -13.00885 18.78674  1.000 47.46844  ? 238 TYR A OH  1 
ATOM   1736 N N   . MET A 1 240 ? -7.64614  -11.23279 16.53019  1.000 41.90883  ? 239 MET A N   1 
ATOM   1737 C CA  . MET A 1 240 ? -9.04625  -11.31157 16.14356  1.000 36.89802  ? 239 MET A CA  1 
ATOM   1738 C C   . MET A 1 240 ? -9.13814  -11.92841 14.75610  1.000 41.79522  ? 239 MET A C   1 
ATOM   1739 O O   . MET A 1 240 ? -8.24409  -11.72176 13.92464  1.000 44.13756  ? 239 MET A O   1 
ATOM   1740 C CB  . MET A 1 240 ? -9.71361  -9.92905  16.16803  1.000 37.39210  ? 239 MET A CB  1 
ATOM   1741 C CG  . MET A 1 240 ? -9.04069  -8.88856  15.29429  1.000 38.01790  ? 239 MET A CG  1 
ATOM   1742 S SD  . MET A 1 240 ? -10.08446 -7.46964  14.82718  1.000 37.58912  ? 239 MET A SD  1 
ATOM   1743 C CE  . MET A 1 240 ? -11.69968 -8.19783  14.61706  1.000 41.24335  ? 239 MET A CE  1 
ATOM   1744 N N   . PRO A 1 241 ? -10.18873 -12.69480 14.48005  1.000 39.51285  ? 240 PRO A N   1 
ATOM   1745 C CA  . PRO A 1 241 ? -10.30089 -13.36568 13.18470  1.000 36.73568  ? 240 PRO A CA  1 
ATOM   1746 C C   . PRO A 1 241 ? -10.90499 -12.45942 12.12075  1.000 36.08448  ? 240 PRO A C   1 
ATOM   1747 O O   . PRO A 1 241 ? -11.64652 -11.51841 12.42243  1.000 35.18994  ? 240 PRO A O   1 
ATOM   1748 C CB  . PRO A 1 241 ? -11.23526 -14.53949 13.49667  1.000 38.07263  ? 240 PRO A CB  1 
ATOM   1749 C CG  . PRO A 1 241 ? -12.15279 -13.97852 14.51154  1.000 32.81824  ? 240 PRO A CG  1 
ATOM   1750 C CD  . PRO A 1 241 ? -11.32008 -13.03176 15.35922  1.000 36.64807  ? 240 PRO A CD  1 
ATOM   1751 N N   . VAL A 1 242 ? -10.57225 -12.76617 10.85771  1.000 32.72125  ? 241 VAL A N   1 
ATOM   1752 C CA  . VAL A 1 242 ? -11.01294 -12.00333 9.68932   1.000 30.03328  ? 241 VAL A CA  1 
ATOM   1753 C C   . VAL A 1 242 ? -11.44550 -12.97696 8.60331   1.000 36.32029  ? 241 VAL A C   1 
ATOM   1754 O O   . VAL A 1 242 ? -10.71059 -13.92114 8.28217   1.000 39.84268  ? 241 VAL A O   1 
ATOM   1755 C CB  . VAL A 1 242 ? -9.90839  -11.07799 9.14022   1.000 29.43756  ? 241 VAL A CB  1 
ATOM   1756 C CG1 . VAL A 1 242 ? -10.43908 -10.29583 7.98207   1.000 36.26774  ? 241 VAL A CG1 1 
ATOM   1757 C CG2 . VAL A 1 242 ? -9.42008  -10.12053 10.19796  1.000 35.12653  ? 241 VAL A CG2 1 
ATOM   1758 N N   . HIS A 1 243 ? -12.63023 -12.74615 8.02812   1.000 35.45051  ? 242 HIS A N   1 
ATOM   1759 C CA  . HIS A 1 243 ? -13.05750 -13.50869 6.84934   1.000 31.69373  ? 242 HIS A CA  1 
ATOM   1760 C C   . HIS A 1 243 ? -12.08307 -13.26631 5.69319   1.000 34.09970  ? 242 HIS A C   1 
ATOM   1761 O O   . HIS A 1 243 ? -11.79800 -12.10059 5.35689   1.000 38.82613  ? 242 HIS A O   1 
ATOM   1762 C CB  . HIS A 1 243 ? -14.47605 -13.09574 6.45415   1.000 31.83242  ? 242 HIS A CB  1 
ATOM   1763 C CG  . HIS A 1 243 ? -15.13297 -14.00889 5.46431   1.000 36.68082  ? 242 HIS A CG  1 
ATOM   1764 N ND1 . HIS A 1 243 ? -14.92678 -13.90793 4.10655   1.000 34.47748  ? 242 HIS A ND1 1 
ATOM   1765 C CD2 . HIS A 1 243 ? -16.01476 -15.02299 5.63435   1.000 36.18319  ? 242 HIS A CD2 1 
ATOM   1766 C CE1 . HIS A 1 243 ? -15.63726 -14.83004 3.48507   1.000 33.06503  ? 242 HIS A CE1 1 
ATOM   1767 N NE2 . HIS A 1 243 ? -16.31040 -15.51819 4.38882   1.000 33.43835  ? 242 HIS A NE2 1 
ATOM   1768 N N   . PRO A 1 244 ? -11.53353 -14.31428 5.07911   1.000 31.07458  ? 243 PRO A N   1 
ATOM   1769 C CA  . PRO A 1 244 ? -10.48416 -14.09040 4.06302   1.000 34.03022  ? 243 PRO A CA  1 
ATOM   1770 C C   . PRO A 1 244 ? -10.91610 -13.16055 2.93384   1.000 35.67391  ? 243 PRO A C   1 
ATOM   1771 O O   . PRO A 1 244 ? -10.07928 -12.41815 2.38277   1.000 30.59183  ? 243 PRO A O   1 
ATOM   1772 C CB  . PRO A 1 244 ? -10.17613 -15.50596 3.55551   1.000 30.14711  ? 243 PRO A CB  1 
ATOM   1773 C CG  . PRO A 1 244 ? -10.56697 -16.40634 4.64324   1.000 33.21217  ? 243 PRO A CG  1 
ATOM   1774 C CD  . PRO A 1 244 ? -11.68549 -15.73440 5.42413   1.000 36.00561  ? 243 PRO A CD  1 
ATOM   1775 N N   . TRP A 1 245 ? -12.21061 -13.16032 2.59650   1.000 32.13799  ? 244 TRP A N   1 
ATOM   1776 C CA  . TRP A 1 245 ? -12.71647 -12.21845 1.60577   1.000 31.40511  ? 244 TRP A CA  1 
ATOM   1777 C C   . TRP A 1 245 ? -12.61525 -10.79354 2.10775   1.000 35.54828  ? 244 TRP A C   1 
ATOM   1778 O O   . TRP A 1 245 ? -12.09289 -9.91890  1.40457   1.000 40.52631  ? 244 TRP A O   1 
ATOM   1779 C CB  . TRP A 1 245 ? -14.16240 -12.53778 1.24665   1.000 32.59545  ? 244 TRP A CB  1 
ATOM   1780 C CG  . TRP A 1 245 ? -14.73167 -11.70227 0.13351   1.000 31.79391  ? 244 TRP A CG  1 
ATOM   1781 C CD1 . TRP A 1 245 ? -14.82241 -12.04817 -1.17328  1.000 32.46711  ? 244 TRP A CD1 1 
ATOM   1782 C CD2 . TRP A 1 245 ? -15.31856 -10.40271 0.24301   1.000 34.75846  ? 244 TRP A CD2 1 
ATOM   1783 N NE1 . TRP A 1 245 ? -15.43452 -11.05322 -1.88988  1.000 32.66039  ? 244 TRP A NE1 1 
ATOM   1784 C CE2 . TRP A 1 245 ? -15.74528 -10.02851 -1.04294  1.000 33.77935  ? 244 TRP A CE2 1 
ATOM   1785 C CE3 . TRP A 1 245 ? -15.52959 -9.51826  1.30452   1.000 32.98288  ? 244 TRP A CE3 1 
ATOM   1786 C CZ2 . TRP A 1 245 ? -16.36986 -8.81595  -1.29569  1.000 32.29078  ? 244 TRP A CZ2 1 
ATOM   1787 C CZ3 . TRP A 1 245 ? -16.14899 -8.31187  1.04829   1.000 32.93214  ? 244 TRP A CZ3 1 
ATOM   1788 C CH2 . TRP A 1 245 ? -16.56155 -7.97229  -0.23598  1.000 31.68501  ? 244 TRP A CH2 1 
ATOM   1789 N N   . GLN A 1 246 ? -13.13333 -10.53412 3.31694   1.000 35.82872  ? 245 GLN A N   1 
ATOM   1790 C CA  . GLN A 1 246 ? -13.12400 -9.17261  3.83471   1.000 36.81282  ? 245 GLN A CA  1 
ATOM   1791 C C   . GLN A 1 246 ? -11.70375 -8.65316  3.92920   1.000 37.79204  ? 245 GLN A C   1 
ATOM   1792 O O   . GLN A 1 246 ? -11.43058 -7.48341  3.62383   1.000 34.86826  ? 245 GLN A O   1 
ATOM   1793 C CB  . GLN A 1 246 ? -13.79421 -9.10434  5.19883   1.000 35.97508  ? 245 GLN A CB  1 
ATOM   1794 C CG  . GLN A 1 246 ? -13.89858 -7.67142  5.72077   1.000 36.53422  ? 245 GLN A CG  1 
ATOM   1795 C CD  . GLN A 1 246 ? -15.23042 -7.04425  5.37971   1.000 38.93537  ? 245 GLN A CD  1 
ATOM   1796 O OE1 . GLN A 1 246 ? -15.91322 -7.50235  4.47111   1.000 36.92352  ? 245 GLN A OE1 1 
ATOM   1797 N NE2 . GLN A 1 246 ? -15.61791 -6.00213  6.12158   1.000 39.78011  ? 245 GLN A NE2 1 
ATOM   1798 N N   . TRP A 1 247 ? -10.77728 -9.52422  4.31377   1.000 37.09676  ? 246 TRP A N   1 
ATOM   1799 C CA  . TRP A 1 247 ? -9.39424  -9.09899  4.43894   1.000 41.10536  ? 246 TRP A CA  1 
ATOM   1800 C C   . TRP A 1 247 ? -8.84705  -8.54502  3.11942   1.000 40.82196  ? 246 TRP A C   1 
ATOM   1801 O O   . TRP A 1 247 ? -8.34816  -7.41211  3.06504   1.000 35.75499  ? 246 TRP A O   1 
ATOM   1802 C CB  . TRP A 1 247 ? -8.54981  -10.25772 4.91055   1.000 36.55232  ? 246 TRP A CB  1 
ATOM   1803 C CG  . TRP A 1 247 ? -7.15399  -9.89690  4.76041   1.000 41.67202  ? 246 TRP A CG  1 
ATOM   1804 C CD1 . TRP A 1 247 ? -6.31108  -10.25132 3.75939   1.000 39.68691  ? 246 TRP A CD1 1 
ATOM   1805 C CD2 . TRP A 1 247 ? -6.42735  -9.03013  5.61663   1.000 45.22059  ? 246 TRP A CD2 1 
ATOM   1806 N NE1 . TRP A 1 247 ? -5.07756  -9.68804  3.96113   1.000 40.25983  ? 246 TRP A NE1 1 
ATOM   1807 C CE2 . TRP A 1 247 ? -5.12158  -8.93591  5.10061   1.000 45.65050  ? 246 TRP A CE2 1 
ATOM   1808 C CE3 . TRP A 1 247 ? -6.74723  -8.34332  6.79113   1.000 41.15402  ? 246 TRP A CE3 1 
ATOM   1809 C CZ2 . TRP A 1 247 ? -4.13587  -8.18287  5.71200   1.000 47.76217  ? 246 TRP A CZ2 1 
ATOM   1810 C CZ3 . TRP A 1 247 ? -5.77888  -7.60119  7.39833   1.000 43.09267  ? 246 TRP A CZ3 1 
ATOM   1811 C CH2 . TRP A 1 247 ? -4.47962  -7.52372  6.86174   1.000 50.95654  ? 246 TRP A CH2 1 
ATOM   1812 N N   . ALA A 1 248 ? -8.92101  -9.34171  2.04036   1.000 39.53113  ? 247 ALA A N   1 
ATOM   1813 C CA  . ALA A 1 248 ? -8.33704  -8.91168  0.76816   1.000 38.90048  ? 247 ALA A CA  1 
ATOM   1814 C C   . ALA A 1 248 ? -9.17253  -7.83528  0.08712   1.000 36.16430  ? 247 ALA A C   1 
ATOM   1815 O O   . ALA A 1 248 ? -8.62193  -6.91761  -0.52548  1.000 33.53300  ? 247 ALA A O   1 
ATOM   1816 C CB  . ALA A 1 248 ? -8.16504  -10.09746 -0.16723  1.000 39.57282  ? 247 ALA A CB  1 
ATOM   1817 N N   . GLU A 1 249 ? -10.49761 -7.92248  0.17538   1.000 33.63125  ? 248 GLU A N   1 
ATOM   1818 C CA  . GLU A 1 249 ? -11.30444 -6.93520  -0.51984  1.000 36.39389  ? 248 GLU A CA  1 
ATOM   1819 C C   . GLU A 1 249 ? -11.43010 -5.63107  0.26075   1.000 37.85329  ? 248 GLU A C   1 
ATOM   1820 O O   . GLU A 1 249 ? -11.56174 -4.56366  -0.34563  1.000 35.50266  ? 248 GLU A O   1 
ATOM   1821 C CB  . GLU A 1 249 ? -12.67096 -7.53303  -0.85758  1.000 39.05933  ? 248 GLU A CB  1 
ATOM   1822 C CG  . GLU A 1 249 ? -12.57362 -8.71926  -1.87520  1.000 46.01981  ? 248 GLU A CG  1 
ATOM   1823 C CD  . GLU A 1 249 ? -12.77115 -8.26501  -3.33611  1.000 53.82492  ? 248 GLU A CD  1 
ATOM   1824 O OE1 . GLU A 1 249 ? -12.88577 -7.02067  -3.54233  1.000 50.89353  ? 248 GLU A OE1 1 
ATOM   1825 O OE2 . GLU A 1 249 ? -12.80217 -9.13934  -4.25689  1.000 51.74751  ? 248 GLU A OE2 1 
ATOM   1826 N N   . LYS A 1 250 ? -11.35066 -5.66033  1.58705   1.000 39.14824  ? 249 LYS A N   1 
ATOM   1827 C CA  . LYS A 1 250 ? -11.59163 -4.40301  2.28575   1.000 39.53655  ? 249 LYS A CA  1 
ATOM   1828 C C   . LYS A 1 250 ? -10.46119 -3.98712  3.22748   1.000 40.41986  ? 249 LYS A C   1 
ATOM   1829 O O   . LYS A 1 250 ? -9.99187  -2.84572  3.15890   1.000 39.57682  ? 249 LYS A O   1 
ATOM   1830 C CB  . LYS A 1 250 ? -12.91883 -4.46850  3.04386   1.000 35.46086  ? 249 LYS A CB  1 
ATOM   1831 C CG  . LYS A 1 250 ? -14.08185 -4.87422  2.17001   1.000 36.47994  ? 249 LYS A CG  1 
ATOM   1832 C CD  . LYS A 1 250 ? -14.93071 -3.68608  1.78503   1.000 42.37453  ? 249 LYS A CD  1 
ATOM   1833 C CE  . LYS A 1 250 ? -15.57261 -3.89753  0.41457   1.000 44.62586  ? 249 LYS A CE  1 
ATOM   1834 N NZ  . LYS A 1 250 ? -15.85527 -2.63571  -0.35006  1.000 44.34119  ? 249 LYS A NZ  1 
ATOM   1835 N N   . ILE A 1 251 ? -10.01149 -4.88128  4.10661   1.000 38.53440  ? 250 ILE A N   1 
ATOM   1836 C CA  . ILE A 1 251 ? -9.09946  -4.45776  5.16438   1.000 36.06249  ? 250 ILE A CA  1 
ATOM   1837 C C   . ILE A 1 251 ? -7.73750  -4.09618  4.57601   1.000 35.13379  ? 250 ILE A C   1 
ATOM   1838 O O   . ILE A 1 251 ? -7.16597  -3.04327  4.88048   1.000 31.47806  ? 250 ILE A O   1 
ATOM   1839 C CB  . ILE A 1 251 ? -8.97213  -5.55160  6.24125   1.000 34.63648  ? 250 ILE A CB  1 
ATOM   1840 C CG1 . ILE A 1 251 ? -10.29878 -5.83688  6.91405   1.000 32.04134  ? 250 ILE A CG1 1 
ATOM   1841 C CG2 . ILE A 1 251 ? -8.08549  -5.04939  7.34435   1.000 37.66817  ? 250 ILE A CG2 1 
ATOM   1842 C CD1 . ILE A 1 251 ? -11.15107 -4.63094  7.04750   1.000 38.65328  ? 250 ILE A CD1 1 
ATOM   1843 N N   . ALA A 1 252 ? -7.19768  -4.96904  3.72057   1.000 40.38041  ? 251 ALA A N   1 
ATOM   1844 C CA  . ALA A 1 252 ? -5.83033  -4.79348  3.23857   1.000 37.37055  ? 251 ALA A CA  1 
ATOM   1845 C C   . ALA A 1 252 ? -5.68109  -3.51380  2.43435   1.000 39.58202  ? 251 ALA A C   1 
ATOM   1846 O O   . ALA A 1 252 ? -4.62712  -2.87270  2.48262   1.000 40.87601  ? 251 ALA A O   1 
ATOM   1847 C CB  . ALA A 1 252 ? -5.40935  -5.99964  2.40704   1.000 35.64835  ? 251 ALA A CB  1 
ATOM   1848 N N   . ARG A 1 253 ? -6.72802  -3.10815  1.71980   1.000 40.48893  ? 252 ARG A N   1 
ATOM   1849 C CA  . ARG A 1 253 ? -6.70389  -1.84537  0.99741   1.000 39.44726  ? 252 ARG A CA  1 
ATOM   1850 C C   . ARG A 1 253 ? -7.13641  -0.65766  1.86440   1.000 38.86757  ? 252 ARG A C   1 
ATOM   1851 O O   . ARG A 1 253 ? -6.40036  0.32657   1.97025   1.000 44.58019  ? 252 ARG A O   1 
ATOM   1852 C CB  . ARG A 1 253 ? -7.58210  -1.95294  -0.25043  1.000 36.12029  ? 252 ARG A CB  1 
ATOM   1853 C CG  . ARG A 1 253 ? -7.28392  -3.16979  -1.10711  1.000 38.89728  ? 252 ARG A CG  1 
ATOM   1854 C CD  . ARG A 1 253 ? -7.53779  -2.86965  -2.57721  1.000 38.38164  ? 252 ARG A CD  1 
ATOM   1855 N NE  . ARG A 1 253 ? -6.70982  -1.77803  -3.08377  1.000 41.68287  ? 252 ARG A NE  1 
ATOM   1856 C CZ  . ARG A 1 253 ? -6.95368  -1.10038  -4.19960  1.000 37.97627  ? 252 ARG A CZ  1 
ATOM   1857 N NH1 . ARG A 1 253 ? -8.03305  -1.32622  -4.92678  1.000 34.00681  ? 252 ARG A NH1 1 
ATOM   1858 N NH2 . ARG A 1 253 ? -6.08981  -0.17463  -4.59642  1.000 44.93149  ? 252 ARG A NH2 1 
ATOM   1859 N N   . ILE A 1 254 ? -8.31676  -0.71799  2.48564   1.000 32.40447  ? 253 ILE A N   1 
ATOM   1860 C CA  . ILE A 1 254 ? -8.85767  0.46293   3.17160   1.000 41.08966  ? 253 ILE A CA  1 
ATOM   1861 C C   . ILE A 1 254 ? -8.04387  0.82145   4.42898   1.000 35.86189  ? 253 ILE A C   1 
ATOM   1862 O O   . ILE A 1 254 ? -7.81137  1.99880   4.72459   1.000 27.96246  ? 253 ILE A O   1 
ATOM   1863 C CB  . ILE A 1 254 ? -10.34705 0.23648   3.49987   1.000 35.09217  ? 253 ILE A CB  1 
ATOM   1864 C CG1 . ILE A 1 254 ? -11.14931 0.20468   2.21260   1.000 23.76316  ? 253 ILE A CG1 1 
ATOM   1865 C CG2 . ILE A 1 254 ? -10.86694 1.30740   4.46728   1.000 27.22832  ? 253 ILE A CG2 1 
ATOM   1866 C CD1 . ILE A 1 254 ? -12.55719 0.56108   2.40804   1.000 29.47025  ? 253 ILE A CD1 1 
ATOM   1867 N N   . TYR A 1 255 ? -7.63465  -0.17171  5.20705   1.000 34.45817  ? 254 TYR A N   1 
ATOM   1868 C CA  . TYR A 1 255 ? -6.75341  0.06897   6.33601   1.000 39.73192  ? 254 TYR A CA  1 
ATOM   1869 C C   . TYR A 1 255 ? -5.28725  -0.03839  5.94344   1.000 45.05359  ? 254 TYR A C   1 
ATOM   1870 O O   . TYR A 1 255 ? -4.45075  -0.45708  6.75479   1.000 45.71077  ? 254 TYR A O   1 
ATOM   1871 C CB  . TYR A 1 255 ? -7.10482  -0.88747  7.47486   1.000 42.08612  ? 254 TYR A CB  1 
ATOM   1872 C CG  . TYR A 1 255 ? -8.42907  -0.54020  8.11803   1.000 40.51264  ? 254 TYR A CG  1 
ATOM   1873 C CD1 . TYR A 1 255 ? -8.80585  0.78084   8.27291   1.000 43.51991  ? 254 TYR A CD1 1 
ATOM   1874 C CD2 . TYR A 1 255 ? -9.30253  -1.52558  8.56645   1.000 41.07952  ? 254 TYR A CD2 1 
ATOM   1875 C CE1 . TYR A 1 255 ? -10.01046 1.11980   8.84913   1.000 46.63339  ? 254 TYR A CE1 1 
ATOM   1876 C CE2 . TYR A 1 255 ? -10.51638 -1.18913  9.15821   1.000 40.92979  ? 254 TYR A CE2 1 
ATOM   1877 C CZ  . TYR A 1 255 ? -10.85764 0.13730   9.28892   1.000 41.69190  ? 254 TYR A CZ  1 
ATOM   1878 O OH  . TYR A 1 255 ? -12.04412 0.50965   9.85530   1.000 42.55253  ? 254 TYR A OH  1 
ATOM   1879 N N   . ALA A 1 256 ? -4.95917  0.34845   4.70681   1.000 46.45145  ? 255 ALA A N   1 
ATOM   1880 C CA  . ALA A 1 256 ? -3.60426  0.16579   4.19612   1.000 47.44177  ? 255 ALA A CA  1 
ATOM   1881 C C   . ALA A 1 256 ? -2.58668  0.90797   5.04918   1.000 49.43020  ? 255 ALA A C   1 
ATOM   1882 O O   . ALA A 1 256 ? -1.50770  0.37341   5.33869   1.000 42.99938  ? 255 ALA A O   1 
ATOM   1883 C CB  . ALA A 1 256 ? -3.51689  0.63317   2.73707   1.000 40.38401  ? 255 ALA A CB  1 
ATOM   1884 N N   . VAL A 1 257 ? -2.91001  2.14429   5.45599   1.000 48.00327  ? 256 VAL A N   1 
ATOM   1885 C CA  . VAL A 1 257 ? -1.96300  2.92379   6.24827   1.000 47.36067  ? 256 VAL A CA  1 
ATOM   1886 C C   . VAL A 1 257 ? -1.74031  2.28224   7.60921   1.000 53.16596  ? 256 VAL A C   1 
ATOM   1887 O O   . VAL A 1 257 ? -0.61288  2.28146   8.12065   1.000 55.39674  ? 256 VAL A O   1 
ATOM   1888 C CB  . VAL A 1 257 ? -2.42739  4.37808   6.39853   1.000 44.57174  ? 256 VAL A CB  1 
ATOM   1889 C CG1 . VAL A 1 257 ? -1.59226  5.05623   7.45170   1.000 38.63181  ? 256 VAL A CG1 1 
ATOM   1890 C CG2 . VAL A 1 257 ? -2.32938  5.11969   5.06230   1.000 44.63586  ? 256 VAL A CG2 1 
ATOM   1891 N N   . ASP A 1 258 ? -2.80096  1.71036   8.21146   1.000 52.28746  ? 257 ASP A N   1 
ATOM   1892 C CA  . ASP A 1 258 ? -2.67304  1.10565   9.54095   1.000 49.43608  ? 257 ASP A CA  1 
ATOM   1893 C C   . ASP A 1 258 ? -1.83819  -0.16383  9.50221   1.000 47.11441  ? 257 ASP A C   1 
ATOM   1894 O O   . ASP A 1 258 ? -1.03105  -0.41477  10.40579  1.000 49.06735  ? 257 ASP A O   1 
ATOM   1895 C CB  . ASP A 1 258 ? -4.04596  0.80260   10.12632  1.000 48.46312  ? 257 ASP A CB  1 
ATOM   1896 C CG  . ASP A 1 258 ? -4.86226  2.04558   10.33225  1.000 60.05690  ? 257 ASP A CG  1 
ATOM   1897 O OD1 . ASP A 1 258 ? -5.12058  2.73601   9.31791   1.000 65.38916  ? 257 ASP A OD1 1 
ATOM   1898 O OD2 . ASP A 1 258 ? -5.22578  2.34552   11.49168  1.000 52.66485  ? 257 ASP A OD2 1 
ATOM   1899 N N   . ILE A 1 259 ? -2.03847  -0.99252  8.48294   1.000 44.93261  ? 258 ILE A N   1 
ATOM   1900 C CA  . ILE A 1 259 ? -1.22633  -2.19533  8.34760   1.000 45.91393  ? 258 ILE A CA  1 
ATOM   1901 C C   . ILE A 1 259 ? 0.22920   -1.81586  8.12635   1.000 47.41365  ? 258 ILE A C   1 
ATOM   1902 O O   . ILE A 1 259 ? 1.15071   -2.45379  8.65994   1.000 45.78955  ? 258 ILE A O   1 
ATOM   1903 C CB  . ILE A 1 259 ? -1.78553  -3.06753  7.20920   1.000 43.30859  ? 258 ILE A CB  1 
ATOM   1904 C CG1 . ILE A 1 259 ? -3.21346  -3.49717  7.54905   1.000 38.89151  ? 258 ILE A CG1 1 
ATOM   1905 C CG2 . ILE A 1 259 ? -0.86873  -4.25151  6.89103   1.000 34.33738  ? 258 ILE A CG2 1 
ATOM   1906 C CD1 . ILE A 1 259 ? -3.94428  -4.09843  6.37859   1.000 38.89089  ? 258 ILE A CD1 1 
ATOM   1907 N N   . ALA A 1 260 ? 0.45479   -0.75939  7.34528   1.000 50.52109  ? 259 ALA A N   1 
ATOM   1908 C CA  . ALA A 1 260 ? 1.80525   -0.25750  7.14004   1.000 49.67082  ? 259 ALA A CA  1 
ATOM   1909 C C   . ALA A 1 260 ? 2.41318   0.13045   8.47064   1.000 52.59617  ? 259 ALA A C   1 
ATOM   1910 O O   . ALA A 1 260 ? 3.41536   -0.44307  8.91400   1.000 57.67480  ? 259 ALA A O   1 
ATOM   1911 C CB  . ALA A 1 260 ? 1.78197   0.93745   6.18128   1.000 48.42954  ? 259 ALA A CB  1 
ATOM   1912 N N   . GLU A 1 261 ? 1.77362   1.04712   9.14322   1.000 52.53645  ? 260 GLU A N   1 
ATOM   1913 C CA  . GLU A 1 261 ? 2.19249   1.57688   10.41224  1.000 53.41077  ? 260 GLU A CA  1 
ATOM   1914 C C   . GLU A 1 261 ? 2.08005   0.56475   11.56183  1.000 50.29271  ? 260 GLU A C   1 
ATOM   1915 O O   . GLU A 1 261 ? 2.18542   1.02968   12.68426  1.000 53.94967  ? 260 GLU A O   1 
ATOM   1916 C CB  . GLU A 1 261 ? 1.37059   2.83596   10.70081  1.000 57.62627  ? 260 GLU A CB  1 
ATOM   1917 C CG  . GLU A 1 261 ? 2.00617   4.10807   10.13287  1.000 56.43794  ? 260 GLU A CG  1 
ATOM   1918 C CD  . GLU A 1 261 ? 1.15090   5.35083   10.34138  1.000 66.56452  ? 260 GLU A CD  1 
ATOM   1919 O OE1 . GLU A 1 261 ? 0.19740   5.31916   11.15937  1.000 63.51830  ? 260 GLU A OE1 1 
ATOM   1920 O OE2 . GLU A 1 261 ? 1.45114   6.37177   9.68902   1.000 71.14542  ? 260 GLU A OE2 1 
ATOM   1921 N N   . GLY A 1 262 ? 1.86057   -0.73324  11.36101  1.000 49.34152  ? 261 GLY A N   1 
ATOM   1922 C CA  . GLY A 1 262 ? 1.93781   -1.70835  12.43217  1.000 48.48753  ? 261 GLY A CA  1 
ATOM   1923 C C   . GLY A 1 262 ? 0.79682   -1.74820  13.43730  1.000 50.01440  ? 261 GLY A C   1 
ATOM   1924 O O   . GLY A 1 262 ? 0.91332   -2.46770  14.43383  1.000 49.75262  ? 261 GLY A O   1 
ATOM   1925 N N   . ARG A 1 263 ? -0.30186  -1.01213  13.23417  1.000 52.06855  ? 262 ARG A N   1 
ATOM   1926 C CA  . ARG A 1 263 ? -1.43403  -1.14371  14.15216  1.000 46.79733  ? 262 ARG A CA  1 
ATOM   1927 C C   . ARG A 1 263 ? -2.31024  -2.35421  13.83313  1.000 49.04625  ? 262 ARG A C   1 
ATOM   1928 O O   . ARG A 1 263 ? -3.06446  -2.80250  14.70176  1.000 51.25680  ? 262 ARG A O   1 
ATOM   1929 C CB  . ARG A 1 263 ? -2.28343  0.12797   14.15050  1.000 45.03252  ? 262 ARG A CB  1 
ATOM   1930 C CG  . ARG A 1 263 ? -1.47230  1.41015   14.27149  1.000 52.52951  ? 262 ARG A CG  1 
ATOM   1931 C CD  . ARG A 1 263 ? -2.30840  2.60054   14.79030  1.000 61.35016  ? 262 ARG A CD  1 
ATOM   1932 N NE  . ARG A 1 263 ? -3.10709  3.20714   13.72777  1.000 70.62678  ? 262 ARG A NE  1 
ATOM   1933 C CZ  . ARG A 1 263 ? -2.62718  3.98903   12.76466  1.000 67.07147  ? 262 ARG A CZ  1 
ATOM   1934 N NH1 . ARG A 1 263 ? -1.35302  4.35343   12.73952  1.000 62.20179  ? 262 ARG A NH1 1 
ATOM   1935 N NH2 . ARG A 1 263 ? -3.44799  4.41518   11.80118  1.000 55.03058  ? 262 ARG A NH2 1 
ATOM   1936 N N   . ILE A 1 264 ? -2.22744  -2.89542  12.62016  1.000 41.93031  ? 263 ILE A N   1 
ATOM   1937 C CA  . ILE A 1 264 ? -2.86499  -4.15639  12.26591  1.000 41.03109  ? 263 ILE A CA  1 
ATOM   1938 C C   . ILE A 1 264 ? -1.78900  -5.05937  11.69401  1.000 43.09533  ? 263 ILE A C   1 
ATOM   1939 O O   . ILE A 1 264 ? -1.06231  -4.65523  10.78128  1.000 46.29015  ? 263 ILE A O   1 
ATOM   1940 C CB  . ILE A 1 264 ? -3.99627  -3.96667  11.23875  1.000 42.08013  ? 263 ILE A CB  1 
ATOM   1941 C CG1 . ILE A 1 264 ? -5.00840  -2.94084  11.72544  1.000 43.94927  ? 263 ILE A CG1 1 
ATOM   1942 C CG2 . ILE A 1 264 ? -4.68554  -5.27550  10.94313  1.000 38.48506  ? 263 ILE A CG2 1 
ATOM   1943 C CD1 . ILE A 1 264 ? -5.99123  -2.54983  10.64643  1.000 44.56974  ? 263 ILE A CD1 1 
ATOM   1944 N N   . VAL A 1 265 ? -1.67578  -6.27070  12.22018  1.000 39.86644  ? 264 VAL A N   1 
ATOM   1945 C CA  . VAL A 1 265 ? -0.58547  -7.14123  11.78695  1.000 39.22621  ? 264 VAL A CA  1 
ATOM   1946 C C   . VAL A 1 265 ? -1.10519  -8.51431  11.39970  1.000 38.34565  ? 264 VAL A C   1 
ATOM   1947 O O   . VAL A 1 265 ? -1.51787  -9.28353  12.27560  1.000 43.02175  ? 264 VAL A O   1 
ATOM   1948 C CB  . VAL A 1 265 ? 0.48459   -7.29877  12.87440  1.000 43.10659  ? 264 VAL A CB  1 
ATOM   1949 C CG1 . VAL A 1 265 ? 1.52120   -8.29913  12.41380  1.000 39.41835  ? 264 VAL A CG1 1 
ATOM   1950 C CG2 . VAL A 1 265 ? 1.12367   -5.96009  13.20242  1.000 45.72374  ? 264 VAL A CG2 1 
ATOM   1951 N N   . PRO A 1 266 ? -1.10988  -8.85583  10.11616  1.000 44.09117  ? 265 PRO A N   1 
ATOM   1952 C CA  . PRO A 1 266 ? -1.36693  -10.24420 9.71323   1.000 41.02217  ? 265 PRO A CA  1 
ATOM   1953 C C   . PRO A 1 266 ? -0.44258  -11.19827 10.45088  1.000 44.36706  ? 265 PRO A C   1 
ATOM   1954 O O   . PRO A 1 266 ? 0.74205   -10.91571 10.62743  1.000 47.91437  ? 265 PRO A O   1 
ATOM   1955 C CB  . PRO A 1 266 ? -1.06627  -10.22876 8.21475   1.000 34.88283  ? 265 PRO A CB  1 
ATOM   1956 C CG  . PRO A 1 266 ? -1.33652  -8.82809  7.79971   1.000 39.01616  ? 265 PRO A CG  1 
ATOM   1957 C CD  . PRO A 1 266 ? -1.04485  -7.93633  8.96709   1.000 41.40547  ? 265 PRO A CD  1 
ATOM   1958 N N   . VAL A 1 267 ? -0.98536  -12.33594 10.88911  1.000 43.02670  ? 266 VAL A N   1 
ATOM   1959 C CA  . VAL A 1 267 ? -0.19198  -13.28115 11.67131  1.000 42.23093  ? 266 VAL A CA  1 
ATOM   1960 C C   . VAL A 1 267 ? -0.39486  -14.70193 11.16108  1.000 47.09669  ? 266 VAL A C   1 
ATOM   1961 O O   . VAL A 1 267 ? 0.28205   -15.63284 11.61493  1.000 54.86442  ? 266 VAL A O   1 
ATOM   1962 C CB  . VAL A 1 267 ? -0.51770  -13.19574 13.17513  1.000 42.49892  ? 266 VAL A CB  1 
ATOM   1963 C CG1 . VAL A 1 267 ? 0.03828   -11.90936 13.79300  1.000 39.30740  ? 266 VAL A CG1 1 
ATOM   1964 C CG2 . VAL A 1 267 ? -2.00300  -13.29403 13.38956  1.000 44.72213  ? 266 VAL A CG2 1 
ATOM   1965 N N   . GLY A 1 268 ? -1.31360  -14.88729 10.22176  1.000 41.60617  ? 267 GLY A N   1 
ATOM   1966 C CA  . GLY A 1 268 ? -1.52024  -16.18554 9.61034   1.000 44.74033  ? 267 GLY A CA  1 
ATOM   1967 C C   . GLY A 1 268 ? -2.93667  -16.69808 9.79817   1.000 49.82211  ? 267 GLY A C   1 
ATOM   1968 O O   . GLY A 1 268 ? -3.83995  -15.98616 10.25216  1.000 46.62219  ? 267 GLY A O   1 
ATOM   1969 N N   . ALA A 1 269 ? -3.12574  -17.96705 9.43574   1.000 48.95882  ? 268 ALA A N   1 
ATOM   1970 C CA  . ALA A 1 269 ? -4.41570  -18.63535 9.51001   1.000 41.73306  ? 268 ALA A CA  1 
ATOM   1971 C C   . ALA A 1 269 ? -4.43020  -19.62671 10.66711  1.000 48.16420  ? 268 ALA A C   1 
ATOM   1972 O O   . ALA A 1 269 ? -3.41586  -20.27271 10.94760  1.000 51.79471  ? 268 ALA A O   1 
ATOM   1973 C CB  . ALA A 1 269 ? -4.71439  -19.36003 8.20448   1.000 40.17396  ? 268 ALA A CB  1 
ATOM   1974 N N   . GLY A 1 270 ? -5.57756  -19.73719 11.34923  1.000 44.23061  ? 269 GLY A N   1 
ATOM   1975 C CA  . GLY A 1 270 ? -5.76021  -20.74826 12.36728  1.000 40.93558  ? 269 GLY A CA  1 
ATOM   1976 C C   . GLY A 1 270 ? -5.86740  -22.13857 11.76083  1.000 40.34985  ? 269 GLY A C   1 
ATOM   1977 O O   . GLY A 1 270 ? -6.31849  -22.31824 10.63137  1.000 40.06535  ? 269 GLY A O   1 
ATOM   1978 N N   . PRO A 1 271 ? -5.48102  -23.16152 12.51343  1.000 42.49582  ? 270 PRO A N   1 
ATOM   1979 C CA  . PRO A 1 271 ? -5.53447  -24.51377 11.93692  1.000 36.54013  ? 270 PRO A CA  1 
ATOM   1980 C C   . PRO A 1 271 ? -6.94711  -24.99715 11.62685  1.000 39.05106  ? 270 PRO A C   1 
ATOM   1981 O O   . PRO A 1 271 ? -7.13934  -25.69994 10.62880  1.000 38.26997  ? 270 PRO A O   1 
ATOM   1982 C CB  . PRO A 1 271 ? -4.85505  -25.37903 13.00811  1.000 37.40872  ? 270 PRO A CB  1 
ATOM   1983 C CG  . PRO A 1 271 ? -4.75843  -24.50433 14.27097  1.000 47.11218  ? 270 PRO A CG  1 
ATOM   1984 C CD  . PRO A 1 271 ? -5.35409  -23.16805 13.98269  1.000 48.70631  ? 270 PRO A CD  1 
ATOM   1985 N N   . ASP A 1 272 ? -7.94412  -24.65022 12.44030  1.000 38.36702  ? 271 ASP A N   1 
ATOM   1986 C CA  . ASP A 1 272 ? -9.27857  -25.21970 12.27844  1.000 38.21559  ? 271 ASP A CA  1 
ATOM   1987 C C   . ASP A 1 272 ? -9.93853  -24.79888 10.96427  1.000 40.76553  ? 271 ASP A C   1 
ATOM   1988 O O   . ASP A 1 272 ? -9.68721  -23.70622 10.44080  1.000 45.21846  ? 271 ASP A O   1 
ATOM   1989 C CB  . ASP A 1 272 ? -10.16799 -24.79564 13.43889  1.000 41.98437  ? 271 ASP A CB  1 
ATOM   1990 C CG  . ASP A 1 272 ? -9.70852  -25.35906 14.76159  1.000 46.20860  ? 271 ASP A CG  1 
ATOM   1991 O OD1 . ASP A 1 272 ? -8.88444  -26.30678 14.74189  1.000 45.99653  ? 271 ASP A OD1 1 
ATOM   1992 O OD2 . ASP A 1 272 ? -10.18913 -24.86090 15.81472  1.000 44.37455  ? 271 ASP A OD2 1 
ATOM   1993 N N   . ARG A 1 273 ? -10.82395 -25.66499 10.45107  1.000 35.17127  ? 272 ARG A N   1 
ATOM   1994 C CA  . ARG A 1 273 ? -11.57594 -25.41464 9.21857   1.000 39.92678  ? 272 ARG A CA  1 
ATOM   1995 C C   . ARG A 1 273 ? -13.03555 -25.10969 9.53551   1.000 38.18478  ? 272 ARG A C   1 
ATOM   1996 O O   . ARG A 1 273 ? -13.63458 -25.76327 10.39131  1.000 36.60330  ? 272 ARG A O   1 
ATOM   1997 C CB  . ARG A 1 273 ? -11.51019 -26.61102 8.25836   1.000 39.26514  ? 272 ARG A CB  1 
ATOM   1998 C CG  . ARG A 1 273 ? -10.14582 -27.25001 8.17554   1.000 42.19070  ? 272 ARG A CG  1 
ATOM   1999 C CD  . ARG A 1 273 ? -9.17288  -26.31113 7.47675   1.000 44.84093  ? 272 ARG A CD  1 
ATOM   2000 N NE  . ARG A 1 273 ? -9.47146  -26.24567 6.05337   1.000 47.39210  ? 272 ARG A NE  1 
ATOM   2001 C CZ  . ARG A 1 273 ? -8.70125  -26.75914 5.10330   1.000 45.62653  ? 272 ARG A CZ  1 
ATOM   2002 N NH1 . ARG A 1 273 ? -7.53270  -27.30947 5.38465   1.000 42.44408  ? 272 ARG A NH1 1 
ATOM   2003 N NH2 . ARG A 1 273 ? -9.11912  -26.72633 3.84111   1.000 44.23948  ? 272 ARG A NH2 1 
ATOM   2004 N N   . TYR A 1 274 ? -13.61361 -24.13639 8.81512   1.000 38.81373  ? 273 TYR A N   1 
ATOM   2005 C CA  . TYR A 1 274 ? -14.94534 -23.60102 9.09283   1.000 38.40027  ? 273 TYR A CA  1 
ATOM   2006 C C   . TYR A 1 274 ? -15.89728 -23.83528 7.92831   1.000 37.12093  ? 273 TYR A C   1 
ATOM   2007 O O   . TYR A 1 274 ? -15.47720 -23.91075 6.77574   1.000 41.97812  ? 273 TYR A O   1 
ATOM   2008 C CB  . TYR A 1 274 ? -14.89407 -22.10339 9.37356   1.000 34.82358  ? 273 TYR A CB  1 
ATOM   2009 C CG  . TYR A 1 274 ? -14.31400 -21.79590 10.72291  1.000 42.98306  ? 273 TYR A CG  1 
ATOM   2010 C CD1 . TYR A 1 274 ? -12.94766 -21.60359 10.87668  1.000 41.74066  ? 273 TYR A CD1 1 
ATOM   2011 C CD2 . TYR A 1 274 ? -15.12079 -21.72627 11.85581  1.000 41.28690  ? 273 TYR A CD2 1 
ATOM   2012 C CE1 . TYR A 1 274 ? -12.39759 -21.34363 12.11225  1.000 40.17882  ? 273 TYR A CE1 1 
ATOM   2013 C CE2 . TYR A 1 274 ? -14.57352 -21.44781 13.09435  1.000 41.30815  ? 273 TYR A CE2 1 
ATOM   2014 C CZ  . TYR A 1 274 ? -13.20817 -21.26015 13.20600  1.000 36.43935  ? 273 TYR A CZ  1 
ATOM   2015 O OH  . TYR A 1 274 ? -12.64613 -20.98779 14.41476  1.000 37.58397  ? 273 TYR A OH  1 
ATOM   2016 N N   . GLN A 1 275 ? -17.18918 -23.94663 8.22858   1.000 32.50226  ? 274 GLN A N   1 
ATOM   2017 C CA  . GLN A 1 275 ? -18.19199 -24.04040 7.18312   1.000 30.02566  ? 274 GLN A CA  1 
ATOM   2018 C C   . GLN A 1 275 ? -19.14079 -22.86277 7.32509   1.000 33.51009  ? 274 GLN A C   1 
ATOM   2019 O O   . GLN A 1 275 ? -19.79353 -22.72675 8.37113   1.000 35.61452  ? 274 GLN A O   1 
ATOM   2020 C CB  . GLN A 1 275 ? -18.96706 -25.35634 7.23971   1.000 33.86037  ? 274 GLN A CB  1 
ATOM   2021 C CG  . GLN A 1 275 ? -20.14641 -25.38091 6.27489   1.000 39.16016  ? 274 GLN A CG  1 
ATOM   2022 C CD  . GLN A 1 275 ? -20.87012 -26.70954 6.21650   1.000 37.27370  ? 274 GLN A CD  1 
ATOM   2023 O OE1 . GLN A 1 275 ? -20.26394 -27.77236 6.26709   1.000 36.41147  ? 274 GLN A OE1 1 
ATOM   2024 N NE2 . GLN A 1 275 ? -22.19185 -26.64645 6.13289   1.000 36.94396  ? 274 GLN A NE2 1 
ATOM   2025 N N   . PRO A 1 276 ? -19.25486 -22.00188 6.31646   1.000 35.57077  ? 275 PRO A N   1 
ATOM   2026 C CA  . PRO A 1 276 ? -20.24664 -20.91485 6.36059   1.000 34.06159  ? 275 PRO A CA  1 
ATOM   2027 C C   . PRO A 1 276 ? -21.65726 -21.43216 6.61054   1.000 34.86431  ? 275 PRO A C   1 
ATOM   2028 O O   . PRO A 1 276 ? -22.06831 -22.45941 6.06792   1.000 38.59614  ? 275 PRO A O   1 
ATOM   2029 C CB  . PRO A 1 276 ? -20.14319 -20.27993 4.97013   1.000 35.94563  ? 275 PRO A CB  1 
ATOM   2030 C CG  . PRO A 1 276 ? -19.28154 -21.17503 4.15573   1.000 34.14400  ? 275 PRO A CG  1 
ATOM   2031 C CD  . PRO A 1 276 ? -18.54158 -22.09869 5.03290   1.000 31.31616  ? 275 PRO A CD  1 
ATOM   2032 N N   . GLN A 1 277 ? -22.40737 -20.71250 7.43732   1.000 35.85929  ? 276 GLN A N   1 
ATOM   2033 C CA  . GLN A 1 277 ? -23.80648 -21.04225 7.67454   1.000 35.75029  ? 276 GLN A CA  1 
ATOM   2034 C C   . GLN A 1 277 ? -24.65977 -20.20456 6.73264   1.000 36.12471  ? 276 GLN A C   1 
ATOM   2035 O O   . GLN A 1 277 ? -24.14350 -19.36976 5.98951   1.000 39.15653  ? 276 GLN A O   1 
ATOM   2036 C CB  . GLN A 1 277 ? -24.19025 -20.79971 9.13384   1.000 34.64789  ? 276 GLN A CB  1 
ATOM   2037 C CG  . GLN A 1 277 ? -23.25430 -21.43055 10.14304  1.000 32.68124  ? 276 GLN A CG  1 
ATOM   2038 C CD  . GLN A 1 277 ? -23.24670 -22.94587 10.05730  1.000 38.50277  ? 276 GLN A CD  1 
ATOM   2039 O OE1 . GLN A 1 277 ? -24.08865 -23.61113 10.66992  1.000 44.45588  ? 276 GLN A OE1 1 
ATOM   2040 N NE2 . GLN A 1 277 ? -22.28156 -23.50526 9.32119   1.000 35.56421  ? 276 GLN A NE2 1 
ATOM   2041 N N   . GLN A 1 278 ? -25.98179 -20.39977 6.77152   1.000 35.57275  ? 277 GLN A N   1 
ATOM   2042 C CA  . GLN A 1 278 ? -26.84167 -19.68713 5.83097   1.000 34.94012  ? 277 GLN A CA  1 
ATOM   2043 C C   . GLN A 1 278 ? -26.60611 -18.18591 5.89996   1.000 34.72572  ? 277 GLN A C   1 
ATOM   2044 O O   . GLN A 1 278 ? -26.72716 -17.49312 4.88700   1.000 43.68541  ? 277 GLN A O   1 
ATOM   2045 C CB  . GLN A 1 278 ? -28.31699 -20.02720 6.07919   1.000 33.08232  ? 277 GLN A CB  1 
ATOM   2046 C CG  . GLN A 1 278 ? -28.70502 -21.41837 5.59708   1.000 34.51104  ? 277 GLN A CG  1 
ATOM   2047 C CD  . GLN A 1 278 ? -30.11106 -21.83529 5.99721   1.000 44.21135  ? 277 GLN A CD  1 
ATOM   2048 O OE1 . GLN A 1 278 ? -30.43372 -21.94328 7.18890   1.000 46.30739  ? 277 GLN A OE1 1 
ATOM   2049 N NE2 . GLN A 1 278 ? -30.96491 -22.07415 4.99342   1.000 43.72475  ? 277 GLN A NE2 1 
ATOM   2050 N N   . SER A 1 279 ? -26.20854 -17.67822 7.06530   1.000 36.23499  ? 278 SER A N   1 
ATOM   2051 C CA  . SER A 1 279 ? -25.86958 -16.26644 7.22636   1.000 40.31382  ? 278 SER A CA  1 
ATOM   2052 C C   . SER A 1 279 ? -24.68502 -15.82003 6.36449   1.000 42.97290  ? 278 SER A C   1 
ATOM   2053 O O   . SER A 1 279 ? -24.48974 -14.61136 6.21224   1.000 47.09654  ? 278 SER A O   1 
ATOM   2054 C CB  . SER A 1 279 ? -25.54496 -15.96667 8.69377   1.000 43.53634  ? 278 SER A CB  1 
ATOM   2055 O OG  . SER A 1 279 ? -26.55642 -16.47314 9.54206   1.000 56.93713  ? 278 SER A OG  1 
ATOM   2056 N N   . ILE A 1 280 ? -23.88692 -16.75044 5.82234   1.000 37.78821  ? 279 ILE A N   1 
ATOM   2057 C CA  . ILE A 1 280 ? -22.71182 -16.47088 4.98977   1.000 37.18636  ? 279 ILE A CA  1 
ATOM   2058 C C   . ILE A 1 280 ? -21.53982 -16.01815 5.85361   1.000 33.44862  ? 279 ILE A C   1 
ATOM   2059 O O   . ILE A 1 280 ? -20.43811 -16.56794 5.75372   1.000 37.96130  ? 279 ILE A O   1 
ATOM   2060 C CB  . ILE A 1 280 ? -22.99165 -15.42472 3.87960   1.000 38.42494  ? 279 ILE A CB  1 
ATOM   2061 C CG1 . ILE A 1 280 ? -24.16333 -15.81931 2.99838   1.000 31.77841  ? 279 ILE A CG1 1 
ATOM   2062 C CG2 . ILE A 1 280 ? -21.78777 -15.22154 2.98206   1.000 35.01634  ? 279 ILE A CG2 1 
ATOM   2063 C CD1 . ILE A 1 280 ? -24.72832 -14.64103 2.29549   1.000 37.94694  ? 279 ILE A CD1 1 
ATOM   2064 N N   . ARG A 1 281 ? -21.75646 -15.00029 6.67986   1.000 31.01328  ? 280 ARG A N   1 
ATOM   2065 C CA  . ARG A 1 281 ? -20.71781 -14.40990 7.51715   1.000 35.33841  ? 280 ARG A CA  1 
ATOM   2066 C C   . ARG A 1 281 ? -20.63518 -15.02051 8.91325   1.000 37.61918  ? 280 ARG A C   1 
ATOM   2067 O O   . ARG A 1 281 ? -19.84499 -14.54472 9.73011   1.000 32.83255  ? 280 ARG A O   1 
ATOM   2068 C CB  . ARG A 1 281 ? -20.95396 -12.91206 7.66068   1.000 37.71211  ? 280 ARG A CB  1 
ATOM   2069 C CG  . ARG A 1 281 ? -22.30251 -12.61867 8.25065   1.000 38.18639  ? 280 ARG A CG  1 
ATOM   2070 C CD  . ARG A 1 281 ? -22.33685 -11.33498 9.02570   1.000 43.20919  ? 280 ARG A CD  1 
ATOM   2071 N NE  . ARG A 1 281 ? -23.63123 -11.19294 9.68060   1.000 45.69538  ? 280 ARG A NE  1 
ATOM   2072 C CZ  . ARG A 1 281 ? -24.19210 -10.03201 9.97599   1.000 42.16111  ? 280 ARG A CZ  1 
ATOM   2073 N NH1 . ARG A 1 281 ? -23.56923 -8.88851  9.74876   1.000 41.05497  ? 280 ARG A NH1 1 
ATOM   2074 N NH2 . ARG A 1 281 ? -25.41040 -10.01834 10.50695  1.000 51.33252  ? 280 ARG A NH2 1 
ATOM   2075 N N   . THR A 1 282 ? -21.43431 -16.03665 9.21935   1.000 38.81726  ? 281 THR A N   1 
ATOM   2076 C CA  . THR A 1 282 ? -21.26437 -16.82727 10.42917  1.000 37.33541  ? 281 THR A CA  1 
ATOM   2077 C C   . THR A 1 282 ? -20.73267 -18.19420 10.02523  1.000 37.12197  ? 281 THR A C   1 
ATOM   2078 O O   . THR A 1 282 ? -21.35774 -18.89324 9.22262   1.000 35.79846  ? 281 THR A O   1 
ATOM   2079 C CB  . THR A 1 282 ? -22.57742 -16.97816 11.19368  1.000 41.58183  ? 281 THR A CB  1 
ATOM   2080 O OG1 . THR A 1 282 ? -23.22409 -15.70848 11.31491  1.000 44.51405  ? 281 THR A OG1 1 
ATOM   2081 C CG2 . THR A 1 282 ? -22.31185 -17.53515 12.56443  1.000 37.14341  ? 281 THR A CG2 1 
ATOM   2082 N N   . VAL A 1 283 ? -19.59174 -18.57859 10.57994  1.000 37.35966  ? 282 VAL A N   1 
ATOM   2083 C CA  . VAL A 1 283 ? -18.98317 -19.85058 10.22601  1.000 37.27687  ? 282 VAL A CA  1 
ATOM   2084 C C   . VAL A 1 283 ? -18.97407 -20.75378 11.45446  1.000 38.29441  ? 282 VAL A C   1 
ATOM   2085 O O   . VAL A 1 283 ? -18.93325 -20.29245 12.60245  1.000 37.83302  ? 282 VAL A O   1 
ATOM   2086 C CB  . VAL A 1 283 ? -17.56423 -19.67210 9.61954   1.000 36.42780  ? 282 VAL A CB  1 
ATOM   2087 C CG1 . VAL A 1 283 ? -17.64865 -18.86017 8.31408   1.000 32.16746  ? 282 VAL A CG1 1 
ATOM   2088 C CG2 . VAL A 1 283 ? -16.61197 -19.01221 10.59378  1.000 29.43977  ? 282 VAL A CG2 1 
ATOM   2089 N N   . PHE A 1 284 ? -19.05618 -22.05724 11.19043  1.000 35.23591  ? 283 PHE A N   1 
ATOM   2090 C CA  . PHE A 1 284 ? -19.11044 -23.10545 12.19533  1.000 28.96849  ? 283 PHE A CA  1 
ATOM   2091 C C   . PHE A 1 284 ? -17.80629 -23.88064 12.15828  1.000 36.38121  ? 283 PHE A C   1 
ATOM   2092 O O   . PHE A 1 284 ? -17.34751 -24.28215 11.08500  1.000 37.15928  ? 283 PHE A O   1 
ATOM   2093 C CB  . PHE A 1 284 ? -20.28419 -24.03891 11.91845  1.000 29.52149  ? 283 PHE A CB  1 
ATOM   2094 C CG  . PHE A 1 284 ? -20.38442 -25.22695 12.84722  1.000 33.96155  ? 283 PHE A CG  1 
ATOM   2095 C CD1 . PHE A 1 284 ? -19.74233 -26.41988 12.55053  1.000 27.85401  ? 283 PHE A CD1 1 
ATOM   2096 C CD2 . PHE A 1 284 ? -21.19362 -25.16999 13.99278  1.000 37.36222  ? 283 PHE A CD2 1 
ATOM   2097 C CE1 . PHE A 1 284 ? -19.86809 -27.52692 13.39463  1.000 34.06422  ? 283 PHE A CE1 1 
ATOM   2098 C CE2 . PHE A 1 284 ? -21.33168 -26.28176 14.84297  1.000 35.02100  ? 283 PHE A CE2 1 
ATOM   2099 C CZ  . PHE A 1 284 ? -20.66206 -27.46342 14.54572  1.000 33.83290  ? 283 PHE A CZ  1 
ATOM   2100 N N   . ASN A 1 285 ? -17.21534 -24.09675 13.32396  1.000 42.31775  ? 284 ASN A N   1 
ATOM   2101 C CA  . ASN A 1 285 ? -15.99075 -24.88392 13.41982  1.000 37.33318  ? 284 ASN A CA  1 
ATOM   2102 C C   . ASN A 1 285 ? -16.31258 -26.34656 13.14622  1.000 34.22533  ? 284 ASN A C   1 
ATOM   2103 O O   . ASN A 1 285 ? -16.88148 -27.02990 13.99422  1.000 36.88029  ? 284 ASN A O   1 
ATOM   2104 C CB  . ASN A 1 285 ? -15.37185 -24.70842 14.79735  1.000 32.86244  ? 284 ASN A CB  1 
ATOM   2105 C CG  . ASN A 1 285 ? -13.93468 -25.09684 14.81957  1.000 36.61128  ? 284 ASN A CG  1 
ATOM   2106 O OD1 . ASN A 1 285 ? -13.54165 -26.10220 14.22525  1.000 34.06968  ? 284 ASN A OD1 1 
ATOM   2107 N ND2 . ASN A 1 285 ? -13.12227 -24.30026 15.49746  1.000 41.63114  ? 284 ASN A ND2 1 
ATOM   2108 N N   . VAL A 1 286 ? -15.95988 -26.84648 11.96027  1.000 34.31185  ? 285 VAL A N   1 
ATOM   2109 C CA  . VAL A 1 286 ? -16.18352 -28.26329 11.69096  1.000 34.82949  ? 285 VAL A CA  1 
ATOM   2110 C C   . VAL A 1 286 ? -15.04378 -29.13933 12.17993  1.000 34.58229  ? 285 VAL A C   1 
ATOM   2111 O O   . VAL A 1 286 ? -15.26900 -30.32975 12.42290  1.000 39.87808  ? 285 VAL A O   1 
ATOM   2112 C CB  . VAL A 1 286 ? -16.43599 -28.58691 10.20475  1.000 34.25395  ? 285 VAL A CB  1 
ATOM   2113 C CG1 . VAL A 1 286 ? -17.73471 -27.98678 9.74821   1.000 32.44075  ? 285 VAL A CG1 1 
ATOM   2114 C CG2 . VAL A 1 286 ? -15.29354 -28.13066 9.33506   1.000 37.43602  ? 285 VAL A CG2 1 
ATOM   2115 N N   . SER A 1 287 ? -13.83798 -28.59168 12.34975  1.000 35.15097  ? 286 SER A N   1 
ATOM   2116 C CA  . SER A 1 287 ? -12.73643 -29.39763 12.88154  1.000 39.77176  ? 286 SER A CA  1 
ATOM   2117 C C   . SER A 1 287 ? -12.97420 -29.75682 14.34244  1.000 36.14013  ? 286 SER A C   1 
ATOM   2118 O O   . SER A 1 287 ? -12.79346 -30.90850 14.74188  1.000 36.53043  ? 286 SER A O   1 
ATOM   2119 C CB  . SER A 1 287 ? -11.39835 -28.66511 12.73777  1.000 40.32017  ? 286 SER A CB  1 
ATOM   2120 O OG  . SER A 1 287 ? -11.17601 -28.21374 11.41614  1.000 39.79533  ? 286 SER A OG  1 
ATOM   2121 N N   . VAL A 1 288 ? -13.37694 -28.77394 15.14450  1.000 40.01055  ? 287 VAL A N   1 
ATOM   2122 C CA  . VAL A 1 288 ? -13.65322 -28.86726 16.58163  1.000 37.39790  ? 287 VAL A CA  1 
ATOM   2123 C C   . VAL A 1 288 ? -15.07491 -28.35922 16.82862  1.000 37.79876  ? 287 VAL A C   1 
ATOM   2124 O O   . VAL A 1 288 ? -15.25026 -27.18245 17.19253  1.000 36.40587  ? 287 VAL A O   1 
ATOM   2125 C CB  . VAL A 1 288 ? -12.62329 -28.04407 17.37989  1.000 36.97471  ? 287 VAL A CB  1 
ATOM   2126 C CG1 . VAL A 1 288 ? -12.83463 -28.15737 18.88030  1.000 31.83395  ? 287 VAL A CG1 1 
ATOM   2127 C CG2 . VAL A 1 288 ? -11.20404 -28.42730 16.97152  1.000 39.21612  ? 287 VAL A CG2 1 
ATOM   2128 N N   . PRO A 1 289 ? -16.11098 -29.18764 16.62282  1.000 36.20655  ? 288 PRO A N   1 
ATOM   2129 C CA  . PRO A 1 289 ? -17.50026 -28.67251 16.63792  1.000 33.48428  ? 288 PRO A CA  1 
ATOM   2130 C C   . PRO A 1 289 ? -17.91587 -28.01161 17.93585  1.000 38.86625  ? 288 PRO A C   1 
ATOM   2131 O O   . PRO A 1 289 ? -18.88571 -27.24731 17.93833  1.000 38.49050  ? 288 PRO A O   1 
ATOM   2132 C CB  . PRO A 1 289 ? -18.35034 -29.91990 16.37278  1.000 30.95386  ? 288 PRO A CB  1 
ATOM   2133 C CG  . PRO A 1 289 ? -17.44585 -30.85141 15.67272  1.000 39.24467  ? 288 PRO A CG  1 
ATOM   2134 C CD  . PRO A 1 289 ? -16.03565 -30.57471 16.13865  1.000 36.92940  ? 288 PRO A CD  1 
ATOM   2135 N N   . THR A 1 290 ? -17.23578 -28.26945 19.04224  1.000 36.84723  ? 289 THR A N   1 
ATOM   2136 C CA  . THR A 1 290 ? -17.65008 -27.60960 20.26358  1.000 34.72674  ? 289 THR A CA  1 
ATOM   2137 C C   . THR A 1 290 ? -17.00273 -26.24442 20.45300  1.000 35.21619  ? 289 THR A C   1 
ATOM   2138 O O   . THR A 1 290 ? -17.50043 -25.46206 21.26731  1.000 43.30493  ? 289 THR A O   1 
ATOM   2139 C CB  . THR A 1 290 ? -17.38414 -28.51732 21.46579  1.000 35.35732  ? 289 THR A CB  1 
ATOM   2140 O OG1 . THR A 1 290 ? -15.98519 -28.73259 21.59737  1.000 44.04704  ? 289 THR A OG1 1 
ATOM   2141 C CG2 . THR A 1 290 ? -18.03601 -29.84930 21.25246  1.000 37.50860  ? 289 THR A CG2 1 
ATOM   2142 N N   . ARG A 1 291 ? -15.94503 -25.91432 19.70900  1.000 33.35964  ? 290 ARG A N   1 
ATOM   2143 C CA  . ARG A 1 291 ? -15.45189 -24.53975 19.69523  1.000 30.79646  ? 290 ARG A CA  1 
ATOM   2144 C C   . ARG A 1 291 ? -16.52532 -23.60703 19.13439  1.000 35.28602  ? 290 ARG A C   1 
ATOM   2145 O O   . ARG A 1 291 ? -17.53809 -24.04397 18.57296  1.000 40.29530  ? 290 ARG A O   1 
ATOM   2146 C CB  . ARG A 1 291 ? -14.16992 -24.44214 18.87751  1.000 33.53144  ? 290 ARG A CB  1 
ATOM   2147 C CG  . ARG A 1 291 ? -12.92188 -24.56978 19.69025  1.000 37.43181  ? 290 ARG A CG  1 
ATOM   2148 C CD  . ARG A 1 291 ? -11.68841 -24.83895 18.84660  1.000 41.98277  ? 290 ARG A CD  1 
ATOM   2149 N NE  . ARG A 1 291 ? -10.49755 -24.90325 19.68897  1.000 43.44356  ? 290 ARG A NE  1 
ATOM   2150 C CZ  . ARG A 1 291 ? -9.27427  -25.19516 19.26705  1.000 44.88116  ? 290 ARG A CZ  1 
ATOM   2151 N NH1 . ARG A 1 291 ? -9.04690  -25.63475 18.03788  1.000 42.92197  ? 290 ARG A NH1 1 
ATOM   2152 N NH2 . ARG A 1 291 ? -8.24975  -25.01769 20.09311  1.000 46.06405  ? 290 ARG A NH2 1 
ATOM   2153 N N   . HIS A 1 292 ? -16.29057 -22.30587 19.26812  1.000 28.38684  ? 291 HIS A N   1 
ATOM   2154 C CA  . HIS A 1 292 ? -17.32419 -21.33560 18.93395  1.000 30.42263  ? 291 HIS A CA  1 
ATOM   2155 C C   . HIS A 1 292 ? -17.52922 -21.16725 17.42913  1.000 38.85081  ? 291 HIS A C   1 
ATOM   2156 O O   . HIS A 1 292 ? -16.58314 -21.24645 16.62916  1.000 38.70816  ? 291 HIS A O   1 
ATOM   2157 C CB  . HIS A 1 292 ? -16.97127 -19.99463 19.55030  1.000 31.61793  ? 291 HIS A CB  1 
ATOM   2158 C CG  . HIS A 1 292 ? -17.05839 -20.00125 21.04168  1.000 46.00672  ? 291 HIS A CG  1 
ATOM   2159 N ND1 . HIS A 1 292 ? -17.95194 -20.80018 21.72676  1.000 45.84627  ? 291 HIS A ND1 1 
ATOM   2160 C CD2 . HIS A 1 292 ? -16.34577 -19.34000 21.98400  1.000 44.48595  ? 291 HIS A CD2 1 
ATOM   2161 C CE1 . HIS A 1 292 ? -17.79939 -20.61241 23.02339  1.000 40.97672  ? 291 HIS A CE1 1 
ATOM   2162 N NE2 . HIS A 1 292 ? -16.83088 -19.73252 23.20655  1.000 37.76408  ? 291 HIS A NE2 1 
ATOM   2163 N N   . TYR A 1 293 ? -18.78869 -20.93567 17.04685  1.000 36.44041  ? 292 TYR A N   1 
ATOM   2164 C CA  . TYR A 1 293 ? -19.05928 -20.19622 15.82359  1.000 33.85952  ? 292 TYR A CA  1 
ATOM   2165 C C   . TYR A 1 293 ? -18.25869 -18.90605 15.85010  1.000 35.95460  ? 292 TYR A C   1 
ATOM   2166 O O   . TYR A 1 293 ? -18.00696 -18.33970 16.91638  1.000 40.61126  ? 292 TYR A O   1 
ATOM   2167 C CB  . TYR A 1 293 ? -20.52438 -19.77993 15.70109  1.000 31.72271  ? 292 TYR A CB  1 
ATOM   2168 C CG  . TYR A 1 293 ? -21.64191 -20.79095 15.54329  1.000 38.11315  ? 292 TYR A CG  1 
ATOM   2169 C CD1 . TYR A 1 293 ? -21.97511 -21.30985 14.29605  1.000 35.61612  ? 292 TYR A CD1 1 
ATOM   2170 C CD2 . TYR A 1 293 ? -22.46615 -21.11917 16.63612  1.000 39.02538  ? 292 TYR A CD2 1 
ATOM   2171 C CE1 . TYR A 1 293 ? -23.05047 -22.19116 14.15418  1.000 40.38548  ? 292 TYR A CE1 1 
ATOM   2172 C CE2 . TYR A 1 293 ? -23.53788 -21.99157 16.50795  1.000 33.20268  ? 292 TYR A CE2 1 
ATOM   2173 C CZ  . TYR A 1 293 ? -23.82573 -22.51867 15.26826  1.000 43.39711  ? 292 TYR A CZ  1 
ATOM   2174 O OH  . TYR A 1 293 ? -24.88694 -23.37502 15.13816  1.000 43.23354  ? 292 TYR A OH  1 
ATOM   2175 N N   . VAL A 1 294 ? -17.91876 -18.39714 14.67109  1.000 37.09492  ? 293 VAL A N   1 
ATOM   2176 C CA  . VAL A 1 294 ? -17.35746 -17.05932 14.51686  1.000 32.94943  ? 293 VAL A CA  1 
ATOM   2177 C C   . VAL A 1 294 ? -18.23696 -16.28006 13.55214  1.000 31.27573  ? 293 VAL A C   1 
ATOM   2178 O O   . VAL A 1 294 ? -18.64104 -16.81096 12.51554  1.000 38.19554  ? 293 VAL A O   1 
ATOM   2179 C CB  . VAL A 1 294 ? -15.91226 -17.10856 14.00046  1.000 34.72906  ? 293 VAL A CB  1 
ATOM   2180 C CG1 . VAL A 1 294 ? -15.36507 -15.69528 13.86953  1.000 35.61069  ? 293 VAL A CG1 1 
ATOM   2181 C CG2 . VAL A 1 294 ? -15.05446 -17.98707 14.90528  1.000 24.45021  ? 293 VAL A CG2 1 
ATOM   2182 N N   . LYS A 1 295 ? -18.55764 -15.04237 13.90543  1.000 32.27533  ? 294 LYS A N   1 
ATOM   2183 C CA  . LYS A 1 295 ? -19.29350 -14.11876 13.04664  1.000 32.51240  ? 294 LYS A CA  1 
ATOM   2184 C C   . LYS A 1 295 ? -18.36553 -12.96943 12.71097  1.000 35.02780  ? 294 LYS A C   1 
ATOM   2185 O O   . LYS A 1 295 ? -17.87810 -12.28874 13.61590  1.000 40.46547  ? 294 LYS A O   1 
ATOM   2186 C CB  . LYS A 1 295 ? -20.55547 -13.57666 13.71840  1.000 33.56057  ? 294 LYS A CB  1 
ATOM   2187 C CG  . LYS A 1 295 ? -21.44947 -12.76858 12.79385  1.000 32.18927  ? 294 LYS A CG  1 
ATOM   2188 C CD  . LYS A 1 295 ? -22.29711 -11.75194 13.53041  1.000 35.39276  ? 294 LYS A CD  1 
ATOM   2189 C CE  . LYS A 1 295 ? -23.74426 -12.19565 13.60792  1.000 43.98588  ? 294 LYS A CE  1 
ATOM   2190 N NZ  . LYS A 1 295 ? -24.78271 -11.11069 13.68133  1.000 46.87511  ? 294 LYS A NZ  1 
ATOM   2191 N N   . THR A 1 296 ? -18.13543 -12.74987 11.41966  1.000 37.83456  ? 295 THR A N   1 
ATOM   2192 C CA  . THR A 1 296 ? -17.16974 -11.78687 10.91814  1.000 33.35016  ? 295 THR A CA  1 
ATOM   2193 C C   . THR A 1 296 ? -17.89284 -10.72140 10.11811  1.000 34.76540  ? 295 THR A C   1 
ATOM   2194 O O   . THR A 1 296 ? -19.01722 -10.92617 9.67027   1.000 41.98289  ? 295 THR A O   1 
ATOM   2195 C CB  . THR A 1 296 ? -16.14452 -12.48879 10.04377  1.000 37.21124  ? 295 THR A CB  1 
ATOM   2196 O OG1 . THR A 1 296 ? -16.84015 -13.30513 9.09978   1.000 35.73055  ? 295 THR A OG1 1 
ATOM   2197 C CG2 . THR A 1 296 ? -15.25631 -13.38482 10.87880  1.000 36.27602  ? 295 THR A CG2 1 
ATOM   2198 N N   . ALA A 1 297 ? -17.25131 -9.57621  9.93699   1.000 38.40424  ? 296 ALA A N   1 
ATOM   2199 C CA  . ALA A 1 297 ? -17.81002 -8.57248  9.03921   1.000 43.66205  ? 296 ALA A CA  1 
ATOM   2200 C C   . ALA A 1 297 ? -17.60972 -9.00179  7.58301   1.000 42.51086  ? 296 ALA A C   1 
ATOM   2201 O O   . ALA A 1 297 ? -16.50073 -9.35916  7.18103   1.000 43.67440  ? 296 ALA A O   1 
ATOM   2202 C CB  . ALA A 1 297 ? -17.16248 -7.21514  9.28928   1.000 38.84629  ? 296 ALA A CB  1 
ATOM   2203 N N   . LEU A 1 298 ? -18.68896 -8.99373  6.79972   1.000 36.23660  ? 297 LEU A N   1 
ATOM   2204 C CA  . LEU A 1 298 ? -18.64047 -9.27819  5.36590   1.000 34.98798  ? 297 LEU A CA  1 
ATOM   2205 C C   . LEU A 1 298 ? -19.30616 -8.10912  4.66502   1.000 37.69077  ? 297 LEU A C   1 
ATOM   2206 O O   . LEU A 1 298 ? -20.52709 -8.09558  4.52546   1.000 37.17732  ? 297 LEU A O   1 
ATOM   2207 C CB  . LEU A 1 298 ? -19.36842 -10.56169 4.99786   1.000 34.44354  ? 297 LEU A CB  1 
ATOM   2208 C CG  . LEU A 1 298 ? -18.60376 -11.79727 4.52498   1.000 33.71570  ? 297 LEU A CG  1 
ATOM   2209 C CD1 . LEU A 1 298 ? -19.57240 -12.77984 3.95525   1.000 31.38016  ? 297 LEU A CD1 1 
ATOM   2210 C CD2 . LEU A 1 298 ? -17.52776 -11.49197 3.54254   1.000 31.83892  ? 297 LEU A CD2 1 
ATOM   2211 N N   . SER A 1 299 ? -18.52379 -7.14515  4.20465   1.000 38.44486  ? 298 SER A N   1 
ATOM   2212 C CA  . SER A 1 299 ? -19.09750 -6.00438  3.51029   1.000 36.14389  ? 298 SER A CA  1 
ATOM   2213 C C   . SER A 1 299 ? -19.58707 -6.37773  2.11578   1.000 37.69994  ? 298 SER A C   1 
ATOM   2214 O O   . SER A 1 299 ? -19.02464 -5.92426  1.12113   1.000 42.69478  ? 298 SER A O   1 
ATOM   2215 C CB  . SER A 1 299 ? -18.06482 -4.88604  3.43756   1.000 39.12012  ? 298 SER A CB  1 
ATOM   2216 O OG  . SER A 1 299 ? -18.03020 -4.17938  4.66713   1.000 48.47929  ? 298 SER A OG  1 
ATOM   2217 N N   . ILE A 1 300 ? -20.61059 -7.22500  2.03265   1.000 39.41828  ? 299 ILE A N   1 
ATOM   2218 C CA  . ILE A 1 300 ? -21.31379 -7.53653  0.79509   1.000 31.26100  ? 299 ILE A CA  1 
ATOM   2219 C C   . ILE A 1 300 ? -22.77606 -7.18360  1.01700   1.000 39.57021  ? 299 ILE A C   1 
ATOM   2220 O O   . ILE A 1 300 ? -23.20625 -6.92556  2.13906   1.000 43.31752  ? 299 ILE A O   1 
ATOM   2221 C CB  . ILE A 1 300 ? -21.16835 -9.01062  0.37496   1.000 31.16390  ? 299 ILE A CB  1 
ATOM   2222 C CG1 . ILE A 1 300 ? -21.79622 -9.94285  1.42005   1.000 31.66533  ? 299 ILE A CG1 1 
ATOM   2223 C CG2 . ILE A 1 300 ? -19.71599 -9.35496  0.14598   1.000 33.66321  ? 299 ILE A CG2 1 
ATOM   2224 C CD1 . ILE A 1 300 ? -22.04246 -11.37529 0.92850   1.000 28.95509  ? 299 ILE A CD1 1 
ATOM   2225 N N   . VAL A 1 301 ? -23.54684 -7.16368  -0.06127  1.000 36.44323  ? 300 VAL A N   1 
ATOM   2226 C CA  . VAL A 1 301 ? -24.94281 -6.76616  0.01984   1.000 38.61603  ? 300 VAL A CA  1 
ATOM   2227 C C   . VAL A 1 301 ? -25.81831 -7.97831  -0.23498  1.000 47.76539  ? 300 VAL A C   1 
ATOM   2228 O O   . VAL A 1 301 ? -25.76375 -8.57514  -1.31862  1.000 53.37275  ? 300 VAL A O   1 
ATOM   2229 C CB  . VAL A 1 301 ? -25.26316 -5.65216  -0.96831  1.000 36.50530  ? 300 VAL A CB  1 
ATOM   2230 C CG1 . VAL A 1 301 ? -26.76763 -5.39487  -0.95452  1.000 51.05246  ? 300 VAL A CG1 1 
ATOM   2231 C CG2 . VAL A 1 301 ? -24.48859 -4.44427  -0.58110  1.000 33.77711  ? 300 VAL A CG2 1 
ATOM   2232 N N   . ASN A 1 302 ? -26.64249 -8.32888  0.74967   1.000 47.64122  ? 301 ASN A N   1 
ATOM   2233 C CA  . ASN A 1 302 ? -27.52752 -9.48359  0.63638   1.000 53.35104  ? 301 ASN A CA  1 
ATOM   2234 C C   . ASN A 1 302 ? -28.90268 -9.12963  1.19390   1.000 64.16889  ? 301 ASN A C   1 
ATOM   2235 O O   . ASN A 1 302 ? -29.04832 -8.90110  2.39892   1.000 61.98426  ? 301 ASN A O   1 
ATOM   2236 C CB  . ASN A 1 302 ? -26.94530 -10.69226 1.34941   1.000 43.46274  ? 301 ASN A CB  1 
ATOM   2237 C CG  . ASN A 1 302 ? -27.38097 -11.96465 0.71228   1.000 48.71849  ? 301 ASN A CG  1 
ATOM   2238 O OD1 . ASN A 1 302 ? -27.61248 -11.99843 -0.49948  1.000 53.16565  ? 301 ASN A OD1 1 
ATOM   2239 N ND2 . ASN A 1 302 ? -27.51370 -13.02410 1.50236   1.000 44.81366  ? 301 ASN A ND2 1 
ATOM   2240 N N   . MET A 1 303 ? -29.91366 -9.11325  0.32012   1.000 67.08455  ? 302 MET A N   1 
ATOM   2241 C CA  . MET A 1 303 ? -31.24805 -8.61066  0.64849   1.000 60.77339  ? 302 MET A CA  1 
ATOM   2242 C C   . MET A 1 303 ? -31.16841 -7.16791  1.15950   1.000 66.91070  ? 302 MET A C   1 
ATOM   2243 O O   . MET A 1 303 ? -31.57995 -6.83679  2.27568   1.000 71.67704  ? 302 MET A O   1 
ATOM   2244 C CB  . MET A 1 303 ? -31.98099 -9.55069  1.62486   1.000 59.89285  ? 302 MET A CB  1 
ATOM   2245 C CG  . MET A 1 303 ? -31.66627 -11.05445 1.38601   1.000 58.11832  ? 302 MET A CG  1 
ATOM   2246 S SD  . MET A 1 303 ? -31.74494 -12.22828 2.78181   1.000 67.29226  ? 302 MET A SD  1 
ATOM   2247 C CE  . MET A 1 303 ? -33.35978 -11.91697 3.47422   1.000 60.26237  ? 302 MET A CE  1 
ATOM   2248 N N   . GLY A 1 304 ? -30.60909 -6.30652  0.29967   1.000 66.42486  ? 303 GLY A N   1 
ATOM   2249 C CA  . GLY A 1 304 ? -30.61186 -4.86790  0.49703   1.000 66.02393  ? 303 GLY A CA  1 
ATOM   2250 C C   . GLY A 1 304 ? -29.74377 -4.34947  1.61900   1.000 69.28136  ? 303 GLY A C   1 
ATOM   2251 O O   . GLY A 1 304 ? -29.53704 -3.12967  1.70021   1.000 70.03548  ? 303 GLY A O   1 
ATOM   2252 N N   . PHE A 1 305 ? -29.21623 -5.22739  2.47104   1.000 68.69287  ? 304 PHE A N   1 
ATOM   2253 C CA  . PHE A 1 305 ? -28.46781 -4.88115  3.67155   1.000 63.56666  ? 304 PHE A CA  1 
ATOM   2254 C C   . PHE A 1 305 ? -26.98730 -5.18763  3.47382   1.000 55.78449  ? 304 PHE A C   1 
ATOM   2255 O O   . PHE A 1 305 ? -26.62421 -6.12999  2.76724   1.000 55.84469  ? 304 PHE A O   1 
ATOM   2256 C CB  . PHE A 1 305 ? -28.98267 -5.69194  4.86304   1.000 66.01543  ? 304 PHE A CB  1 
ATOM   2257 C CG  . PHE A 1 305 ? -30.17068 -5.09157  5.54853   1.000 79.38858  ? 304 PHE A CG  1 
ATOM   2258 C CD1 . PHE A 1 305 ? -31.42600 -5.14782  4.95208   1.000 83.18458  ? 304 PHE A CD1 1 
ATOM   2259 C CD2 . PHE A 1 305 ? -30.05460 -4.51897  6.81074   1.000 81.15157  ? 304 PHE A CD2 1 
ATOM   2260 C CE1 . PHE A 1 305 ? -32.53865 -4.60588  5.59014   1.000 87.94598  ? 304 PHE A CE1 1 
ATOM   2261 C CE2 . PHE A 1 305 ? -31.16218 -3.97776  7.45472   1.000 79.35023  ? 304 PHE A CE2 1 
ATOM   2262 C CZ  . PHE A 1 305 ? -32.40676 -4.02048  6.84406   1.000 81.46336  ? 304 PHE A CZ  1 
ATOM   2263 N N   . THR A 1 306 ? -26.12714 -4.39867  4.10302   1.000 53.20914  ? 305 THR A N   1 
ATOM   2264 C CA  . THR A 1 306 ? -24.71732 -4.75728  4.16466   1.000 49.81438  ? 305 THR A CA  1 
ATOM   2265 C C   . THR A 1 306 ? -24.48030 -5.65527  5.36422   1.000 49.44234  ? 305 THR A C   1 
ATOM   2266 O O   . THR A 1 306 ? -25.16870 -5.56091  6.38031   1.000 55.01453  ? 305 THR A O   1 
ATOM   2267 C CB  . THR A 1 306 ? -23.82591 -3.51704  4.24381   1.000 52.71059  ? 305 THR A CB  1 
ATOM   2268 O OG1 . THR A 1 306 ? -23.92549 -2.80704  3.00661   1.000 52.60233  ? 305 THR A OG1 1 
ATOM   2269 C CG2 . THR A 1 306 ? -22.34298 -3.87776  4.49518   1.000 49.63550  ? 305 THR A CG2 1 
ATOM   2270 N N   . ARG A 1 307 ? -23.50987 -6.54636  5.22899   1.000 46.88255  ? 306 ARG A N   1 
ATOM   2271 C CA  . ARG A 1 307 ? -23.19783 -7.52608  6.25475   1.000 44.29879  ? 306 ARG A CA  1 
ATOM   2272 C C   . ARG A 1 307 ? -21.88801 -7.21258  6.97501   1.000 43.27371  ? 306 ARG A C   1 
ATOM   2273 O O   . ARG A 1 307 ? -21.22372 -8.11411  7.49529   1.000 46.24459  ? 306 ARG A O   1 
ATOM   2274 C CB  . ARG A 1 307 ? -23.17852 -8.91960  5.63382   1.000 45.78346  ? 306 ARG A CB  1 
ATOM   2275 C CG  . ARG A 1 307 ? -24.50299 -9.27205  5.00108   1.000 47.32804  ? 306 ARG A CG  1 
ATOM   2276 C CD  . ARG A 1 307 ? -25.61162 -8.80304  5.91428   1.000 51.89338  ? 306 ARG A CD  1 
ATOM   2277 N NE  . ARG A 1 307 ? -26.92736 -9.22005  5.45894   1.000 65.08555  ? 306 ARG A NE  1 
ATOM   2278 C CZ  . ARG A 1 307 ? -28.05045 -8.90792  6.08801   1.000 71.72798  ? 306 ARG A CZ  1 
ATOM   2279 N NH1 . ARG A 1 307 ? -28.03930 -8.16293  7.18242   1.000 74.20439  ? 306 ARG A NH1 1 
ATOM   2280 N NH2 . ARG A 1 307 ? -29.21174 -9.34675  5.60465   1.000 68.12918  ? 306 ARG A NH2 1 
ATOM   2281 N N   . GLY A 1 308 ? -21.50341 -5.94135  7.00886   1.000 44.59560  ? 307 GLY A N   1 
ATOM   2282 C CA  . GLY A 1 308 ? -20.46481 -5.50371  7.91084   1.000 44.36822  ? 307 GLY A CA  1 
ATOM   2283 C C   . GLY A 1 308 ? -20.95998 -5.54153  9.35113   1.000 50.20713  ? 307 GLY A C   1 
ATOM   2284 O O   . GLY A 1 308 ? -22.09839 -5.90823  9.65697   1.000 46.99069  ? 307 GLY A O   1 
ATOM   2285 N N   . MET A 1 309 ? -20.06836 -5.14835  10.25703  1.000 47.90262  ? 308 MET A N   1 
ATOM   2286 C CA  . MET A 1 309 ? -20.39727 -5.06399  11.67668  1.000 43.01921  ? 308 MET A CA  1 
ATOM   2287 C C   . MET A 1 309 ? -19.65751 -3.88575  12.27376  1.000 46.21484  ? 308 MET A C   1 
ATOM   2288 O O   . MET A 1 309 ? -18.42631 -3.84449  12.19472  1.000 47.32187  ? 308 MET A O   1 
ATOM   2289 C CB  . MET A 1 309 ? -20.01025 -6.34038  12.40379  1.000 43.17662  ? 308 MET A CB  1 
ATOM   2290 C CG  . MET A 1 309 ? -21.13634 -7.28191  12.64684  1.000 39.84563  ? 308 MET A CG  1 
ATOM   2291 S SD  . MET A 1 309 ? -20.46738 -8.92742  12.57288  1.000 51.21560  ? 308 MET A SD  1 
ATOM   2292 C CE  . MET A 1 309 ? -19.58043 -9.10202  14.11024  1.000 42.82347  ? 308 MET A CE  1 
ATOM   2293 N N   . SER A 1 310 ? -20.39182 -2.95418  12.88394  1.000 46.98290  ? 309 SER A N   1 
ATOM   2294 C CA  . SER A 1 310 ? -19.74710 -1.81177  13.52126  1.000 49.14016  ? 309 SER A CA  1 
ATOM   2295 C C   . SER A 1 310 ? -19.03671 -2.24742  14.79647  1.000 42.96410  ? 309 SER A C   1 
ATOM   2296 O O   . SER A 1 310 ? -19.50585 -3.13041  15.51299  1.000 43.06682  ? 309 SER A O   1 
ATOM   2297 C CB  . SER A 1 310 ? -20.76872 -0.70977  13.82255  1.000 50.18620  ? 309 SER A CB  1 
ATOM   2298 O OG  . SER A 1 310 ? -21.45573 -0.93069  15.03753  1.000 52.02280  ? 309 SER A OG  1 
ATOM   2299 N N   . ALA A 1 311 ? -17.86385 -1.66054  15.04779  1.000 48.94994  ? 310 ALA A N   1 
ATOM   2300 C CA  . ALA A 1 311 ? -17.23229 -1.81166  16.35755  1.000 53.97177  ? 310 ALA A CA  1 
ATOM   2301 C C   . ALA A 1 311 ? -18.11358 -1.21321  17.43420  1.000 55.21246  ? 310 ALA A C   1 
ATOM   2302 O O   . ALA A 1 311 ? -18.09523 -1.65369  18.59308  1.000 51.19831  ? 310 ALA A O   1 
ATOM   2303 C CB  . ALA A 1 311 ? -15.85390 -1.14225  16.38199  1.000 49.49165  ? 310 ALA A CB  1 
ATOM   2304 N N   . ASP A 1 312 ? -18.89207 -0.20696  17.05402  1.000 54.22803  ? 311 ASP A N   1 
ATOM   2305 C CA  . ASP A 1 312 ? -19.88031 0.36297   17.94747  1.000 52.67941  ? 311 ASP A CA  1 
ATOM   2306 C C   . ASP A 1 312 ? -20.75987 -0.73309  18.53462  1.000 52.23931  ? 311 ASP A C   1 
ATOM   2307 O O   . ASP A 1 312 ? -20.88415 -0.85440  19.75551  1.000 62.21921  ? 311 ASP A O   1 
ATOM   2308 C CB  . ASP A 1 312 ? -20.67778 1.41040   17.17063  1.000 67.11609  ? 311 ASP A CB  1 
ATOM   2309 C CG  . ASP A 1 312 ? -19.77155 2.24805   16.21183  1.000 74.85028  ? 311 ASP A CG  1 
ATOM   2310 O OD1 . ASP A 1 312 ? -18.68572 2.70450   16.65265  1.000 72.63330  ? 311 ASP A OD1 1 
ATOM   2311 O OD2 . ASP A 1 312 ? -20.12572 2.42303   15.01392  1.000 65.45677  ? 311 ASP A OD2 1 
ATOM   2312 N N   . TYR A 1 313 ? -21.31995 -1.59224  17.68737  1.000 50.57790  ? 312 TYR A N   1 
ATOM   2313 C CA  . TYR A 1 313 ? -22.14799 -2.67442  18.20699  1.000 52.34098  ? 312 TYR A CA  1 
ATOM   2314 C C   . TYR A 1 313 ? -21.33462 -3.71828  18.94177  1.000 49.49254  ? 312 TYR A C   1 
ATOM   2315 O O   . TYR A 1 313 ? -21.87058 -4.42461  19.80300  1.000 50.64876  ? 312 TYR A O   1 
ATOM   2316 C CB  . TYR A 1 313 ? -22.91683 -3.33514  17.07858  1.000 51.35749  ? 312 TYR A CB  1 
ATOM   2317 C CG  . TYR A 1 313 ? -24.16877 -2.58871  16.74959  1.000 54.24038  ? 312 TYR A CG  1 
ATOM   2318 C CD1 . TYR A 1 313 ? -24.25781 -1.21170  16.97437  1.000 53.75508  ? 312 TYR A CD1 1 
ATOM   2319 C CD2 . TYR A 1 313 ? -25.27854 -3.25490  16.24433  1.000 54.11463  ? 312 TYR A CD2 1 
ATOM   2320 C CE1 . TYR A 1 313 ? -25.41488 -0.51822  16.68095  1.000 56.85915  ? 312 TYR A CE1 1 
ATOM   2321 C CE2 . TYR A 1 313 ? -26.44163 -2.57257  15.94530  1.000 58.39429  ? 312 TYR A CE2 1 
ATOM   2322 C CZ  . TYR A 1 313 ? -26.50325 -1.20804  16.15996  1.000 59.74296  ? 312 TYR A CZ  1 
ATOM   2323 O OH  . TYR A 1 313 ? -27.66290 -0.54051  15.86125  1.000 62.16190  ? 312 TYR A OH  1 
ATOM   2324 N N   . MET A 1 314 ? -20.05315 -3.81647  18.62552  1.000 50.13181  ? 313 MET A N   1 
ATOM   2325 C CA  . MET A 1 314 ? -19.24064 -4.86235  19.20712  1.000 50.37536  ? 313 MET A CA  1 
ATOM   2326 C C   . MET A 1 314 ? -19.12130 -4.61822  20.70440  1.000 49.28492  ? 313 MET A C   1 
ATOM   2327 O O   . MET A 1 314 ? -19.13323 -5.56265  21.49923  1.000 45.72910  ? 313 MET A O   1 
ATOM   2328 C CB  . MET A 1 314 ? -17.87982 -4.85482  18.51165  1.000 47.69445  ? 313 MET A CB  1 
ATOM   2329 C CG  . MET A 1 314 ? -17.86992 -5.63043  17.18047  1.000 49.13525  ? 313 MET A CG  1 
ATOM   2330 S SD  . MET A 1 314 ? -18.96120 -7.05781  17.00281  1.000 44.29752  ? 313 MET A SD  1 
ATOM   2331 C CE  . MET A 1 314 ? -20.28870 -6.35433  16.01256  1.000 45.97000  ? 313 MET A CE  1 
ATOM   2332 N N   . ARG A 1 315 ? -19.05970 -3.33341  21.09363  1.000 54.26090  ? 314 ARG A N   1 
ATOM   2333 C CA  . ARG A 1 315 ? -19.00618 -2.93024  22.50082  1.000 48.37030  ? 314 ARG A CA  1 
ATOM   2334 C C   . ARG A 1 315 ? -20.19303 -3.47307  23.27789  1.000 47.78455  ? 314 ARG A C   1 
ATOM   2335 O O   . ARG A 1 315 ? -20.03394 -4.05949  24.35384  1.000 46.94871  ? 314 ARG A O   1 
ATOM   2336 C CB  . ARG A 1 315 ? -19.00776 -1.40434  22.61593  1.000 48.69885  ? 314 ARG A CB  1 
ATOM   2337 C CG  . ARG A 1 315 ? -17.68277 -0.69928  22.47005  1.000 52.53693  ? 314 ARG A CG  1 
ATOM   2338 C CD  . ARG A 1 315 ? -17.92658 0.80402   22.32865  1.000 55.22768  ? 314 ARG A CD  1 
ATOM   2339 N NE  . ARG A 1 315 ? -17.11054 1.37353   21.26422  1.000 62.77498  ? 314 ARG A NE  1 
ATOM   2340 C CZ  . ARG A 1 315 ? -17.59157 2.09511   20.26008  1.000 69.32819  ? 314 ARG A CZ  1 
ATOM   2341 N NH1 . ARG A 1 315 ? -18.88093 2.38832   20.18266  1.000 69.97028  ? 314 ARG A NH1 1 
ATOM   2342 N NH2 . ARG A 1 315 ? -16.75828 2.53115   19.30913  1.000 62.59890  ? 314 ARG A NH2 1 
ATOM   2343 N N   . THR A 1 316 ? -21.39828 -3.26341  22.75740  1.000 43.79013  ? 315 THR A N   1 
ATOM   2344 C CA  . THR A 1 316 ? -22.59192 -3.50292  23.54438  1.000 43.76154  ? 315 THR A CA  1 
ATOM   2345 C C   . THR A 1 316 ? -23.16520 -4.90003  23.38879  1.000 44.99188  ? 315 THR A C   1 
ATOM   2346 O O   . THR A 1 316 ? -23.86223 -5.35564  24.29800  1.000 47.60708  ? 315 THR A O   1 
ATOM   2347 C CB  . THR A 1 316 ? -23.68243 -2.49866  23.18167  1.000 46.24084  ? 315 THR A CB  1 
ATOM   2348 O OG1 . THR A 1 316 ? -23.79217 -2.41174  21.75973  1.000 51.03685  ? 315 THR A OG1 1 
ATOM   2349 C CG2 . THR A 1 316 ? -23.35172 -1.15048  23.74425  1.000 45.36155  ? 315 THR A CG2 1 
ATOM   2350 N N   . THR A 1 317 ? -22.91490 -5.59015  22.27703  1.000 43.48681  ? 316 THR A N   1 
ATOM   2351 C CA  . THR A 1 317 ? -23.62926 -6.84709  22.05299  1.000 44.29972  ? 316 THR A CA  1 
ATOM   2352 C C   . THR A 1 317 ? -23.37843 -7.87753  23.15350  1.000 43.65664  ? 316 THR A C   1 
ATOM   2353 O O   . THR A 1 317 ? -24.36609 -8.43064  23.67270  1.000 43.69986  ? 316 THR A O   1 
ATOM   2354 C CB  . THR A 1 317 ? -23.32281 -7.39337  20.65010  1.000 45.77276  ? 316 THR A CB  1 
ATOM   2355 O OG1 . THR A 1 317 ? -23.91464 -6.53804  19.65834  1.000 55.57205  ? 316 THR A OG1 1 
ATOM   2356 C CG2 . THR A 1 317 ? -23.90211 -8.77904  20.47829  1.000 37.45249  ? 316 THR A CG2 1 
ATOM   2357 N N   . PRO A 1 318 ? -22.13715 -8.16368  23.58418  1.000 37.78677  ? 317 PRO A N   1 
ATOM   2358 C CA  . PRO A 1 318 ? -21.96913 -9.10035  24.71142  1.000 40.30146  ? 317 PRO A CA  1 
ATOM   2359 C C   . PRO A 1 318 ? -22.68228 -8.66411  25.97929  1.000 43.87276  ? 317 PRO A C   1 
ATOM   2360 O O   . PRO A 1 318 ? -23.10590 -9.51838  26.77276  1.000 39.75970  ? 317 PRO A O   1 
ATOM   2361 C CB  . PRO A 1 318 ? -20.44750 -9.14429  24.90937  1.000 38.32428  ? 317 PRO A CB  1 
ATOM   2362 C CG  . PRO A 1 318 ? -19.90010 -8.85070  23.59455  1.000 37.76822  ? 317 PRO A CG  1 
ATOM   2363 C CD  . PRO A 1 318 ? -20.83815 -7.84512  22.97016  1.000 39.51167  ? 317 PRO A CD  1 
ATOM   2364 N N   . LEU A 1 319 ? -22.83268 -7.35340  26.18457  1.000 44.41459  ? 318 LEU A N   1 
ATOM   2365 C CA  . LEU A 1 319 ? -23.51209 -6.84393  27.37346  1.000 39.68731  ? 318 LEU A CA  1 
ATOM   2366 C C   . LEU A 1 319 ? -25.00574 -7.11275  27.32096  1.000 40.56174  ? 318 LEU A C   1 
ATOM   2367 O O   . LEU A 1 319 ? -25.57671 -7.63849  28.27724  1.000 43.47934  ? 318 LEU A O   1 
ATOM   2368 C CB  . LEU A 1 319 ? -23.23037 -5.35130  27.52997  1.000 45.13148  ? 318 LEU A CB  1 
ATOM   2369 C CG  . LEU A 1 319 ? -21.75340 -4.93826  27.45123  1.000 50.28144  ? 318 LEU A CG  1 
ATOM   2370 C CD1 . LEU A 1 319 ? -21.57514 -3.56347  28.03068  1.000 42.12527  ? 318 LEU A CD1 1 
ATOM   2371 C CD2 . LEU A 1 319 ? -20.85671 -5.93094  28.21471  1.000 34.78296  ? 318 LEU A CD2 1 
ATOM   2372 N N   . ILE A 1 320 ? -25.65790 -6.75742  26.21135  1.000 48.38936  ? 319 ILE A N   1 
ATOM   2373 C CA  . ILE A 1 320 ? -27.06965 -7.09513  26.03012  1.000 43.93742  ? 319 ILE A CA  1 
ATOM   2374 C C   . ILE A 1 320 ? -27.29287 -8.57330  26.30420  1.000 43.54664  ? 319 ILE A C   1 
ATOM   2375 O O   . ILE A 1 320 ? -28.28591 -8.96494  26.92657  1.000 48.65373  ? 319 ILE A O   1 
ATOM   2376 C CB  . ILE A 1 320 ? -27.54030 -6.71066  24.61370  1.000 46.12509  ? 319 ILE A CB  1 
ATOM   2377 C CG1 . ILE A 1 320 ? -27.24409 -5.23679  24.31852  1.000 45.66474  ? 319 ILE A CG1 1 
ATOM   2378 C CG2 . ILE A 1 320 ? -29.02552 -7.00585  24.43989  1.000 44.33143  ? 319 ILE A CG2 1 
ATOM   2379 C CD1 . ILE A 1 320 ? -27.91198 -4.73585  23.06704  1.000 47.55831  ? 319 ILE A CD1 1 
ATOM   2380 N N   . ASN A 1 321 ? -26.35434 -9.41507  25.87488  1.000 42.12969  ? 320 ASN A N   1 
ATOM   2381 C CA  . ASN A 1 321 ? -26.51514 -10.85236 26.06400  1.000 45.25947  ? 320 ASN A CA  1 
ATOM   2382 C C   . ASN A 1 321 ? -26.46993 -11.22322 27.53844  1.000 48.09443  ? 320 ASN A C   1 
ATOM   2383 O O   . ASN A 1 321 ? -27.25138 -12.06252 27.99735  1.000 49.49486  ? 320 ASN A O   1 
ATOM   2384 C CB  . ASN A 1 321 ? -25.43720 -11.60612 25.28589  1.000 45.82079  ? 320 ASN A CB  1 
ATOM   2385 C CG  . ASN A 1 321 ? -25.78294 -11.76495 23.81934  1.000 45.18846  ? 320 ASN A CG  1 
ATOM   2386 O OD1 . ASN A 1 321 ? -25.59977 -12.83025 23.23444  1.000 45.79613  ? 320 ASN A OD1 1 
ATOM   2387 N ND2 . ASN A 1 321 ? -26.30583 -10.70642 23.22383  1.000 45.29580  ? 320 ASN A ND2 1 
ATOM   2388 N N   . ASP A 1 322 ? -25.55786 -10.61135 28.29439  1.000 49.33819  ? 321 ASP A N   1 
ATOM   2389 C CA  . ASP A 1 322 ? -25.47944 -10.87516 29.72586  1.000 43.22091  ? 321 ASP A CA  1 
ATOM   2390 C C   . ASP A 1 322 ? -26.77678 -10.48681 30.42705  1.000 46.54673  ? 321 ASP A C   1 
ATOM   2391 O O   . ASP A 1 322 ? -27.25608 -11.19932 31.32056  1.000 48.91435  ? 321 ASP A O   1 
ATOM   2392 C CB  . ASP A 1 322 ? -24.29599 -10.11559 30.31380  1.000 43.41228  ? 321 ASP A CB  1 
ATOM   2393 C CG  . ASP A 1 322 ? -23.48446 -10.95221 31.26970  1.000 57.78554  ? 321 ASP A CG  1 
ATOM   2394 O OD1 . ASP A 1 322 ? -23.73663 -12.18081 31.36849  1.000 61.34281  ? 321 ASP A OD1 1 
ATOM   2395 O OD2 . ASP A 1 322 ? -22.58914 -10.37373 31.92466  1.000 58.55498  ? 321 ASP A OD2 1 
ATOM   2396 N N   . TRP A 1 323 ? -27.36380 -9.36126  30.03502  1.000 41.97808  ? 322 TRP A N   1 
ATOM   2397 C CA  . TRP A 1 323 ? -28.65654 -8.99368  30.58721  1.000 48.59545  ? 322 TRP A CA  1 
ATOM   2398 C C   . TRP A 1 323 ? -29.68509 -10.08646 30.31947  1.000 53.14127  ? 322 TRP A C   1 
ATOM   2399 O O   . TRP A 1 323 ? -30.26091 -10.66102 31.25437  1.000 53.31750  ? 322 TRP A O   1 
ATOM   2400 C CB  . TRP A 1 323 ? -29.11903 -7.65541  30.01191  1.000 50.69427  ? 322 TRP A CB  1 
ATOM   2401 C CG  . TRP A 1 323 ? -30.30914 -7.11848  30.76252  1.000 58.83546  ? 322 TRP A CG  1 
ATOM   2402 C CD1 . TRP A 1 323 ? -30.31999 -6.60578  32.02969  1.000 54.98925  ? 322 TRP A CD1 1 
ATOM   2403 C CD2 . TRP A 1 323 ? -31.66310 -7.07414  30.29997  1.000 54.63778  ? 322 TRP A CD2 1 
ATOM   2404 N NE1 . TRP A 1 323 ? -31.59776 -6.23905  32.37751  1.000 61.57922  ? 322 TRP A NE1 1 
ATOM   2405 C CE2 . TRP A 1 323 ? -32.43842 -6.51460  31.33169  1.000 57.06044  ? 322 TRP A CE2 1 
ATOM   2406 C CE3 . TRP A 1 323 ? -32.29267 -7.45629  29.11364  1.000 49.85266  ? 322 TRP A CE3 1 
ATOM   2407 C CZ2 . TRP A 1 323 ? -33.80659 -6.32482  31.21143  1.000 61.37576  ? 322 TRP A CZ2 1 
ATOM   2408 C CZ3 . TRP A 1 323 ? -33.64815 -7.26720  28.99471  1.000 52.18586  ? 322 TRP A CZ3 1 
ATOM   2409 C CH2 . TRP A 1 323 ? -34.39429 -6.70588  30.03502  1.000 57.86782  ? 322 TRP A CH2 1 
ATOM   2410 N N   . VAL A 1 324 ? -29.90509 -10.40556 29.03798  1.000 49.13563  ? 323 VAL A N   1 
ATOM   2411 C CA  . VAL A 1 324 ? -30.90224 -11.41199 28.67420  1.000 51.87536  ? 323 VAL A CA  1 
ATOM   2412 C C   . VAL A 1 324 ? -30.65530 -12.71786 29.42183  1.000 51.26804  ? 323 VAL A C   1 
ATOM   2413 O O   . VAL A 1 324 ? -31.59288 -13.32701 29.95569  1.000 49.31925  ? 323 VAL A O   1 
ATOM   2414 C CB  . VAL A 1 324 ? -30.92312 -11.63386 27.14699  1.000 45.71562  ? 323 VAL A CB  1 
ATOM   2415 C CG1 . VAL A 1 324 ? -31.75364 -12.88006 26.79394  1.000 41.42187  ? 323 VAL A CG1 1 
ATOM   2416 C CG2 . VAL A 1 324 ? -31.47342 -10.41201 26.43989  1.000 37.18551  ? 323 VAL A CG2 1 
ATOM   2417 N N   . ARG A 1 325 ? -29.39290 -13.16561 29.48477  1.000 48.70120  ? 324 ARG A N   1 
ATOM   2418 C CA  . ARG A 1 325 ? -29.11958 -14.45066 30.12004  1.000 49.12980  ? 324 ARG A CA  1 
ATOM   2419 C C   . ARG A 1 325 ? -29.52223 -14.44662 31.58526  1.000 49.53369  ? 324 ARG A C   1 
ATOM   2420 O O   . ARG A 1 325 ? -29.95534 -15.48429 32.10769  1.000 46.77318  ? 324 ARG A O   1 
ATOM   2421 C CB  . ARG A 1 325 ? -27.64619 -14.84383 29.99574  1.000 49.45378  ? 324 ARG A CB  1 
ATOM   2422 C CG  . ARG A 1 325 ? -27.26652 -15.99307 30.94172  1.000 42.92212  ? 324 ARG A CG  1 
ATOM   2423 C CD  . ARG A 1 325 ? -25.92891 -16.58737 30.61986  1.000 47.62777  ? 324 ARG A CD  1 
ATOM   2424 N NE  . ARG A 1 325 ? -24.86311 -15.66615 30.98994  1.000 63.84717  ? 324 ARG A NE  1 
ATOM   2425 C CZ  . ARG A 1 325 ? -23.71825 -16.02307 31.55477  1.000 64.98125  ? 324 ARG A CZ  1 
ATOM   2426 N NH1 . ARG A 1 325 ? -23.45059 -17.29004 31.83718  1.000 60.90997  ? 324 ARG A NH1 1 
ATOM   2427 N NH2 . ARG A 1 325 ? -22.81999 -15.08420 31.84384  1.000 58.38434  ? 324 ARG A NH2 1 
ATOM   2428 N N   . SER A 1 326 ? -29.41372 -13.29667 32.25914  1.000 48.34207  ? 325 SER A N   1 
ATOM   2429 C CA  . SER A 1 326 ? -29.72327 -13.26311 33.68204  1.000 49.36054  ? 325 SER A CA  1 
ATOM   2430 C C   . SER A 1 326 ? -31.20174 -13.02770 33.96912  1.000 50.28361  ? 325 SER A C   1 
ATOM   2431 O O   . SER A 1 326 ? -31.66430 -13.41608 35.04533  1.000 55.98796  ? 325 SER A O   1 
ATOM   2432 C CB  . SER A 1 326 ? -28.86187 -12.21818 34.39296  1.000 48.50167  ? 325 SER A CB  1 
ATOM   2433 O OG  . SER A 1 326 ? -29.34429 -10.91759 34.15934  1.000 53.11790  ? 325 SER A OG  1 
ATOM   2434 N N   . ARG A 1 327 ? -31.95528 -12.42982 33.03663  1.000 48.48901  ? 326 ARG A N   1 
ATOM   2435 C CA  . ARG A 1 327 ? -33.42063 -12.45218 33.10967  1.000 45.78706  ? 326 ARG A CA  1 
ATOM   2436 C C   . ARG A 1 327 ? -33.97294 -13.87638 33.00827  1.000 49.62841  ? 326 ARG A C   1 
ATOM   2437 O O   . ARG A 1 327 ? -34.89647 -14.24789 33.74236  1.000 54.16640  ? 326 ARG A O   1 
ATOM   2438 C CB  . ARG A 1 327 ? -34.01220 -11.61055 31.98651  1.000 49.91547  ? 326 ARG A CB  1 
ATOM   2439 C CG  . ARG A 1 327 ? -33.85557 -10.13806 32.09445  1.000 52.67908  ? 326 ARG A CG  1 
ATOM   2440 C CD  . ARG A 1 327 ? -34.66547 -9.60465  33.20601  1.000 63.40110  ? 326 ARG A CD  1 
ATOM   2441 N NE  . ARG A 1 327 ? -33.85776 -8.76139  34.06859  1.000 75.73929  ? 326 ARG A NE  1 
ATOM   2442 C CZ  . ARG A 1 327 ? -34.36163 -7.99272  35.02080  1.000 76.54229  ? 326 ARG A CZ  1 
ATOM   2443 N NH1 . ARG A 1 327 ? -35.66800 -7.93357  35.23784  1.000 69.75657  ? 326 ARG A NH1 1 
ATOM   2444 N NH2 . ARG A 1 327 ? -33.53778 -7.25294  35.75939  1.000 76.68485  ? 326 ARG A NH2 1 
ATOM   2445 N N   . VAL A 1 328 ? -33.44754 -14.67905 32.07195  1.000 47.90178  ? 327 VAL A N   1 
ATOM   2446 C CA  . VAL A 1 328 ? -33.95152 -16.03193 31.83633  1.000 47.75201  ? 327 VAL A CA  1 
ATOM   2447 C C   . VAL A 1 328 ? -33.16253 -17.09042 32.57944  1.000 48.77625  ? 327 VAL A C   1 
ATOM   2448 O O   . VAL A 1 328 ? -33.53262 -18.26746 32.52042  1.000 54.11517  ? 327 VAL A O   1 
ATOM   2449 C CB  . VAL A 1 328 ? -33.98699 -16.39938 30.33436  1.000 46.75382  ? 327 VAL A CB  1 
ATOM   2450 C CG1 . VAL A 1 328 ? -34.85180 -15.42840 29.53684  1.000 46.81306  ? 327 VAL A CG1 1 
ATOM   2451 C CG2 . VAL A 1 328 ? -32.60294 -16.44762 29.77494  1.000 47.32565  ? 327 VAL A CG2 1 
ATOM   2452 N N   . HIS A 1 329 ? -32.07869 -16.72158 33.25749  1.000 55.17396  ? 328 HIS A N   1 
ATOM   2453 C CA  . HIS A 1 329 ? -31.34691 -17.68293 34.07533  1.000 57.18328  ? 328 HIS A CA  1 
ATOM   2454 C C   . HIS A 1 329 ? -32.28113 -18.27596 35.12069  1.000 57.28996  ? 328 HIS A C   1 
ATOM   2455 O O   . HIS A 1 329 ? -33.01024 -17.54864 35.80111  1.000 57.13622  ? 328 HIS A O   1 
ATOM   2456 C CB  . HIS A 1 329 ? -30.13765 -17.00851 34.73919  1.000 57.80903  ? 328 HIS A CB  1 
ATOM   2457 C CG  . HIS A 1 329 ? -29.64774 -17.68480 35.98833  1.000 62.86818  ? 328 HIS A CG  1 
ATOM   2458 N ND1 . HIS A 1 329 ? -30.29510 -17.58190 37.20192  1.000 64.66473  ? 328 HIS A ND1 1 
ATOM   2459 C CD2 . HIS A 1 329 ? -28.54246 -18.43169 36.21986  1.000 66.65392  ? 328 HIS A CD2 1 
ATOM   2460 C CE1 . HIS A 1 329 ? -29.62826 -18.25922 38.11862  1.000 65.46062  ? 328 HIS A CE1 1 
ATOM   2461 N NE2 . HIS A 1 329 ? -28.55969 -18.78416 37.54876  1.000 66.67895  ? 328 HIS A NE2 1 
ATOM   2462 N N   . GLY A 1 330 ? -32.28160 -19.60594 35.21300  1.000 59.39181  ? 329 GLY A N   1 
ATOM   2463 C CA  . GLY A 1 330 ? -33.06033 -20.31281 36.20666  1.000 50.53515  ? 329 GLY A CA  1 
ATOM   2464 C C   . GLY A 1 330 ? -34.54994 -20.37264 35.96050  1.000 49.51181  ? 329 GLY A C   1 
ATOM   2465 O O   . GLY A 1 330 ? -35.30690 -20.56343 36.91674  1.000 53.74681  ? 329 GLY A O   1 
ATOM   2466 N N   . ASP A 1 331 ? -35.00634 -20.22213 34.71690  1.000 46.20654  ? 330 ASP A N   1 
ATOM   2467 C CA  . ASP A 1 331 ? -36.44594 -20.18913 34.46887  1.000 44.25354  ? 330 ASP A CA  1 
ATOM   2468 C C   . ASP A 1 331 ? -37.00890 -21.60453 34.45763  1.000 43.61947  ? 330 ASP A C   1 
ATOM   2469 O O   . ASP A 1 331 ? -36.63789 -22.40421 33.59316  1.000 43.82852  ? 330 ASP A O   1 
ATOM   2470 C CB  . ASP A 1 331 ? -36.77442 -19.49603 33.15916  1.000 43.75716  ? 330 ASP A CB  1 
ATOM   2471 C CG  . ASP A 1 331 ? -38.26405 -19.15851 33.03597  1.000 49.89363  ? 330 ASP A CG  1 
ATOM   2472 O OD1 . ASP A 1 331 ? -39.08802 -20.09792 32.86301  1.000 45.92191  ? 330 ASP A OD1 1 
ATOM   2473 O OD2 . ASP A 1 331 ? -38.60981 -17.95220 33.10446  1.000 48.46074  ? 330 ASP A OD2 1 
ATOM   2474 N N   . PRO A 1 332 ? -37.92019 -21.93905 35.36214  1.000 40.11057  ? 331 PRO A N   1 
ATOM   2475 C CA  . PRO A 1 332 ? -38.38013 -23.32695 35.45379  1.000 42.82186  ? 331 PRO A CA  1 
ATOM   2476 C C   . PRO A 1 332 ? -39.17163 -23.80630 34.24523  1.000 41.40972  ? 331 PRO A C   1 
ATOM   2477 O O   . PRO A 1 332 ? -39.10642 -24.99562 33.92456  1.000 41.93293  ? 331 PRO A O   1 
ATOM   2478 C CB  . PRO A 1 332 ? -39.24424 -23.31850 36.72157  1.000 41.74844  ? 331 PRO A CB  1 
ATOM   2479 C CG  . PRO A 1 332 ? -38.92759 -22.05650 37.40628  1.000 44.24599  ? 331 PRO A CG  1 
ATOM   2480 C CD  . PRO A 1 332 ? -38.55967 -21.08165 36.35872  1.000 40.78731  ? 331 PRO A CD  1 
ATOM   2481 N N   . TYR A 1 333 ? -39.94281 -22.94642 33.58223  1.000 41.44963  ? 332 TYR A N   1 
ATOM   2482 C CA  . TYR A 1 333 ? -40.70339 -23.41046 32.42894  1.000 39.37053  ? 332 TYR A CA  1 
ATOM   2483 C C   . TYR A 1 333 ? -39.78266 -23.67731 31.25140  1.000 41.93233  ? 332 TYR A C   1 
ATOM   2484 O O   . TYR A 1 333 ? -39.84104 -24.74667 30.62962  1.000 37.35245  ? 332 TYR A O   1 
ATOM   2485 C CB  . TYR A 1 333 ? -41.76374 -22.39150 32.03921  1.000 39.29018  ? 332 TYR A CB  1 
ATOM   2486 C CG  . TYR A 1 333 ? -42.41331 -22.73699 30.72803  1.000 42.53876  ? 332 TYR A CG  1 
ATOM   2487 C CD1 . TYR A 1 333 ? -43.04907 -23.95776 30.56052  1.000 42.54845  ? 332 TYR A CD1 1 
ATOM   2488 C CD2 . TYR A 1 333 ? -42.38062 -21.85176 29.64314  1.000 41.67239  ? 332 TYR A CD2 1 
ATOM   2489 C CE1 . TYR A 1 333 ? -43.65709 -24.29253 29.35407  1.000 44.46698  ? 332 TYR A CE1 1 
ATOM   2490 C CE2 . TYR A 1 333 ? -42.99261 -22.17778 28.42896  1.000 37.83164  ? 332 TYR A CE2 1 
ATOM   2491 C CZ  . TYR A 1 333 ? -43.62017 -23.40737 28.28875  1.000 39.65849  ? 332 TYR A CZ  1 
ATOM   2492 O OH  . TYR A 1 333 ? -44.21911 -23.77664 27.09907  1.000 40.25645  ? 332 TYR A OH  1 
ATOM   2493 N N   . LEU A 1 334 ? -38.92572 -22.70185 30.93237  1.000 42.38977  ? 333 LEU A N   1 
ATOM   2494 C CA  . LEU A 1 334 ? -37.92946 -22.88855 29.88681  1.000 35.24255  ? 333 LEU A CA  1 
ATOM   2495 C C   . LEU A 1 334 ? -37.06233 -24.10442 30.16253  1.000 33.49637  ? 333 LEU A C   1 
ATOM   2496 O O   . LEU A 1 334 ? -36.71865 -24.84807 29.24429  1.000 39.09231  ? 333 LEU A O   1 
ATOM   2497 C CB  . LEU A 1 334 ? -37.06881 -21.63789 29.76096  1.000 34.88790  ? 333 LEU A CB  1 
ATOM   2498 C CG  . LEU A 1 334 ? -37.84070 -20.44747 29.20617  1.000 34.03383  ? 333 LEU A CG  1 
ATOM   2499 C CD1 . LEU A 1 334 ? -36.99201 -19.21025 29.29686  1.000 33.22178  ? 333 LEU A CD1 1 
ATOM   2500 C CD2 . LEU A 1 334 ? -38.29225 -20.70315 27.77230  1.000 34.39779  ? 333 LEU A CD2 1 
ATOM   2501 N N   . ALA A 1 335 ? -36.69484 -24.33360 31.41620  1.000 36.47628  ? 334 ALA A N   1 
ATOM   2502 C CA  . ALA A 1 335 ? -35.91997 -25.53276 31.68779  1.000 34.42594  ? 334 ALA A CA  1 
ATOM   2503 C C   . ALA A 1 335 ? -36.74069 -26.77646 31.44588  1.000 36.10164  ? 334 ALA A C   1 
ATOM   2504 O O   . ALA A 1 335 ? -36.19782 -27.80733 31.04146  1.000 40.62182  ? 334 ALA A O   1 
ATOM   2505 C CB  . ALA A 1 335 ? -35.40030 -25.53796 33.10785  1.000 28.39086  ? 334 ALA A CB  1 
ATOM   2506 N N   . SER A 1 336 ? -38.04409 -26.69877 31.66108  1.000 36.07636  ? 335 SER A N   1 
ATOM   2507 C CA  . SER A 1 336 ? -38.83383 -27.91361 31.59335  1.000 35.26906  ? 335 SER A CA  1 
ATOM   2508 C C   . SER A 1 336 ? -39.06756 -28.33947 30.15553  1.000 41.40249  ? 335 SER A C   1 
ATOM   2509 O O   . SER A 1 336 ? -39.22692 -29.53740 29.89678  1.000 50.95525  ? 335 SER A O   1 
ATOM   2510 C CB  . SER A 1 336 ? -40.15532 -27.72749 32.34803  1.000 39.42956  ? 335 SER A CB  1 
ATOM   2511 O OG  . SER A 1 336 ? -41.20035 -27.25646 31.51461  1.000 45.61224  ? 335 SER A OG  1 
ATOM   2512 N N   . ILE A 1 337 ? -39.06668 -27.38733 29.21184  1.000 38.38433  ? 336 ILE A N   1 
ATOM   2513 C CA  . ILE A 1 337 ? -39.21621 -27.69808 27.78920  1.000 36.06301  ? 336 ILE A CA  1 
ATOM   2514 C C   . ILE A 1 337 ? -37.87240 -27.82029 27.05464  1.000 36.40200  ? 336 ILE A C   1 
ATOM   2515 O O   . ILE A 1 337 ? -37.85032 -28.21751 25.87662  1.000 39.61083  ? 336 ILE A O   1 
ATOM   2516 C CB  . ILE A 1 337 ? -40.13013 -26.66189 27.08582  1.000 33.22288  ? 336 ILE A CB  1 
ATOM   2517 C CG1 . ILE A 1 337 ? -39.41417 -25.35079 26.80151  1.000 29.99375  ? 336 ILE A CG1 1 
ATOM   2518 C CG2 . ILE A 1 337 ? -41.36176 -26.36965 27.90868  1.000 32.85963  ? 336 ILE A CG2 1 
ATOM   2519 C CD1 . ILE A 1 337 ? -40.34237 -24.34512 26.17098  1.000 31.11883  ? 336 ILE A CD1 1 
ATOM   2520 N N   . GLY A 1 338 ? -36.75944 -27.52214 27.70878  1.000 34.49746  ? 337 GLY A N   1 
ATOM   2521 C CA  . GLY A 1 338 ? -35.48341 -27.70244 27.07010  1.000 31.15623  ? 337 GLY A CA  1 
ATOM   2522 C C   . GLY A 1 338 ? -35.02803 -26.54464 26.22209  1.000 36.40217  ? 337 GLY A C   1 
ATOM   2523 O O   . GLY A 1 338 ? -34.02073 -26.67700 25.51353  1.000 39.18368  ? 337 GLY A O   1 
ATOM   2524 N N   . PHE A 1 339 ? -35.72222 -25.41260 26.27257  1.000 31.31411  ? 338 PHE A N   1 
ATOM   2525 C CA  . PHE A 1 339 ? -35.38798 -24.28218 25.41171  1.000 36.49148  ? 338 PHE A CA  1 
ATOM   2526 C C   . PHE A 1 339 ? -34.04991 -23.67834 25.81138  1.000 35.43050  ? 338 PHE A C   1 
ATOM   2527 O O   . PHE A 1 339 ? -33.93524 -23.09300 26.88697  1.000 42.28458  ? 338 PHE A O   1 
ATOM   2528 C CB  . PHE A 1 339 ? -36.47625 -23.22633 25.49530  1.000 34.97945  ? 338 PHE A CB  1 
ATOM   2529 C CG  . PHE A 1 339 ? -36.23690 -22.06991 24.60567  1.000 36.59323  ? 338 PHE A CG  1 
ATOM   2530 C CD1 . PHE A 1 339 ? -36.37990 -22.19970 23.23914  1.000 34.76222  ? 338 PHE A CD1 1 
ATOM   2531 C CD2 . PHE A 1 339 ? -35.86907 -20.84628 25.12543  1.000 38.89021  ? 338 PHE A CD2 1 
ATOM   2532 C CE1 . PHE A 1 339 ? -36.17408 -21.12005 22.40597  1.000 36.50623  ? 338 PHE A CE1 1 
ATOM   2533 C CE2 . PHE A 1 339 ? -35.65495 -19.75211 24.29407  1.000 38.52735  ? 338 PHE A CE2 1 
ATOM   2534 C CZ  . PHE A 1 339 ? -35.80442 -19.89145 22.93386  1.000 36.98028  ? 338 PHE A CZ  1 
ATOM   2535 N N   . GLU A 1 340 ? -33.04333 -23.79027 24.94762  1.000 39.40439  ? 339 GLU A N   1 
ATOM   2536 C CA  . GLU A 1 340 ? -31.78942 -23.05890 25.11033  1.000 42.53900  ? 339 GLU A CA  1 
ATOM   2537 C C   . GLU A 1 340 ? -31.70935 -21.81425 24.23417  1.000 40.12037  ? 339 GLU A C   1 
ATOM   2538 O O   . GLU A 1 340 ? -32.42982 -21.65311 23.24651  1.000 41.09695  ? 339 GLU A O   1 
ATOM   2539 C CB  . GLU A 1 340 ? -30.56201 -23.93261 24.82165  1.000 44.00789  ? 339 GLU A CB  1 
ATOM   2540 C CG  . GLU A 1 340 ? -30.09066 -24.81508 25.97313  1.000 53.38194  ? 339 GLU A CG  1 
ATOM   2541 C CD  . GLU A 1 340 ? -30.14241 -26.30447 25.65768  1.000 63.16608  ? 339 GLU A CD  1 
ATOM   2542 O OE1 . GLU A 1 340 ? -30.23814 -26.68939 24.46187  1.000 65.03588  ? 339 GLU A OE1 1 
ATOM   2543 O OE2 . GLU A 1 340 ? -30.03108 -27.09329 26.62254  1.000 62.23825  ? 339 GLU A OE2 1 
ATOM   2544 N N   . MET A 1 341 ? -30.81780 -20.92410 24.65081  1.000 37.57652  ? 340 MET A N   1 
ATOM   2545 C CA  . MET A 1 341 ? -30.32382 -19.79693 23.88639  1.000 35.77406  ? 340 MET A CA  1 
ATOM   2546 C C   . MET A 1 341 ? -28.82039 -19.99488 23.80377  1.000 43.43877  ? 340 MET A C   1 
ATOM   2547 O O   . MET A 1 341 ? -28.19102 -20.41641 24.78836  1.000 43.87582  ? 340 MET A O   1 
ATOM   2548 C CB  . MET A 1 341 ? -30.60293 -18.47664 24.58997  1.000 36.06226  ? 340 MET A CB  1 
ATOM   2549 C CG  . MET A 1 341 ? -32.03627 -18.22809 25.00349  1.000 43.82993  ? 340 MET A CG  1 
ATOM   2550 S SD  . MET A 1 341 ? -32.52590 -16.51847 24.73814  1.000 55.52163  ? 340 MET A SD  1 
ATOM   2551 C CE  . MET A 1 341 ? -33.70188 -16.32295 26.06814  1.000 48.59727  ? 340 MET A CE  1 
ATOM   2552 N N   . ILE A 1 342 ? -28.23480 -19.71784 22.64337  1.000 38.57707  ? 341 ILE A N   1 
ATOM   2553 C CA  . ILE A 1 342 ? -26.78425 -19.71067 22.51525  1.000 36.12500  ? 341 ILE A CA  1 
ATOM   2554 C C   . ILE A 1 342 ? -26.35673 -18.26890 22.30146  1.000 37.46493  ? 341 ILE A C   1 
ATOM   2555 O O   . ILE A 1 342 ? -26.85284 -17.57932 21.40015  1.000 41.98136  ? 341 ILE A O   1 
ATOM   2556 C CB  . ILE A 1 342 ? -26.29208 -20.63108 21.39449  1.000 36.03752  ? 341 ILE A CB  1 
ATOM   2557 C CG1 . ILE A 1 342 ? -27.14248 -20.43850 20.13393  1.000 37.25820  ? 341 ILE A CG1 1 
ATOM   2558 C CG2 . ILE A 1 342 ? -26.30054 -22.05858 21.89326  1.000 35.15378  ? 341 ILE A CG2 1 
ATOM   2559 C CD1 . ILE A 1 342 ? -26.69561 -21.22929 18.98996  1.000 28.23298  ? 341 ILE A CD1 1 
ATOM   2560 N N   . TYR A 1 343 ? -25.45586 -17.80484 23.13912  1.000 36.51127  ? 342 TYR A N   1 
ATOM   2561 C CA  . TYR A 1 343 ? -25.20516 -16.38423 23.19700  1.000 37.13220  ? 342 TYR A CA  1 
ATOM   2562 C C   . TYR A 1 343 ? -23.96740 -15.99951 22.40367  1.000 39.02796  ? 342 TYR A C   1 
ATOM   2563 O O   . TYR A 1 343 ? -23.09958 -16.82659 22.09174  1.000 33.14567  ? 342 TYR A O   1 
ATOM   2564 C CB  . TYR A 1 343 ? -25.05773 -15.94998 24.64427  1.000 38.40024  ? 342 TYR A CB  1 
ATOM   2565 C CG  . TYR A 1 343 ? -26.30295 -16.14933 25.45632  1.000 43.09230  ? 342 TYR A CG  1 
ATOM   2566 C CD1 . TYR A 1 343 ? -27.39682 -15.30580 25.31864  1.000 43.37542  ? 342 TYR A CD1 1 
ATOM   2567 C CD2 . TYR A 1 343 ? -26.39316 -17.18692 26.35198  1.000 43.82997  ? 342 TYR A CD2 1 
ATOM   2568 C CE1 . TYR A 1 343 ? -28.53710 -15.50058 26.06739  1.000 42.26240  ? 342 TYR A CE1 1 
ATOM   2569 C CE2 . TYR A 1 343 ? -27.52002 -17.37899 27.10155  1.000 41.66840  ? 342 TYR A CE2 1 
ATOM   2570 C CZ  . TYR A 1 343 ? -28.58461 -16.54147 26.95961  1.000 41.51022  ? 342 TYR A CZ  1 
ATOM   2571 O OH  . TYR A 1 343 ? -29.70638 -16.76938 27.72158  1.000 46.20038  ? 342 TYR A OH  1 
ATOM   2572 N N   . GLU A 1 344 ? -23.91822 -14.71443 22.06621  1.000 37.63132  ? 343 GLU A N   1 
ATOM   2573 C CA  . GLU A 1 344 ? -22.71469 -14.07488 21.55465  1.000 39.22871  ? 343 GLU A CA  1 
ATOM   2574 C C   . GLU A 1 344 ? -21.87182 -13.73024 22.77051  1.000 36.26892  ? 343 GLU A C   1 
ATOM   2575 O O   . GLU A 1 344 ? -22.12845 -12.74331 23.45493  1.000 39.76657  ? 343 GLU A O   1 
ATOM   2576 C CB  . GLU A 1 344 ? -23.06900 -12.84781 20.71795  1.000 38.56300  ? 343 GLU A CB  1 
ATOM   2577 C CG  . GLU A 1 344 ? -23.82080 -13.18612 19.43387  1.000 39.60389  ? 343 GLU A CG  1 
ATOM   2578 C CD  . GLU A 1 344 ? -25.32038 -13.03205 19.56564  1.000 47.03642  ? 343 GLU A CD  1 
ATOM   2579 O OE1 . GLU A 1 344 ? -25.76611 -11.89748 19.86388  1.000 38.32946  ? 343 GLU A OE1 1 
ATOM   2580 O OE2 . GLU A 1 344 ? -26.04435 -14.05157 19.37984  1.000 51.00025  ? 343 GLU A OE2 1 
ATOM   2581 N N   . VAL A 1 345 ? -20.87801 -14.56881 23.07043  1.000 38.55681  ? 344 VAL A N   1 
ATOM   2582 C CA  . VAL A 1 345 ? -20.17333 -14.45554 24.34360  1.000 38.84670  ? 344 VAL A CA  1 
ATOM   2583 C C   . VAL A 1 345 ? -19.07064 -13.41356 24.33558  1.000 42.34543  ? 344 VAL A C   1 
ATOM   2584 O O   . VAL A 1 345 ? -18.59277 -13.04191 25.41974  1.000 41.07420  ? 344 VAL A O   1 
ATOM   2585 C CB  . VAL A 1 345 ? -19.52408 -15.78249 24.77259  1.000 28.63675  ? 344 VAL A CB  1 
ATOM   2586 C CG1 . VAL A 1 345 ? -20.57375 -16.83875 24.87783  1.000 30.05709  ? 344 VAL A CG1 1 
ATOM   2587 C CG2 . VAL A 1 345 ? -18.40892 -16.16658 23.77807  1.000 37.68672  ? 344 VAL A CG2 1 
ATOM   2588 N N   . ALA A 1 346 ? -18.61984 -12.95765 23.16425  1.000 35.21500  ? 345 ALA A N   1 
ATOM   2589 C CA  . ALA A 1 346 ? -17.54002 -11.97967 23.13779  1.000 37.23992  ? 345 ALA A CA  1 
ATOM   2590 C C   . ALA A 1 346 ? -17.48553 -11.31575 21.77201  1.000 36.93713  ? 345 ALA A C   1 
ATOM   2591 O O   . ALA A 1 346 ? -17.71249 -11.96893 20.76115  1.000 37.74498  ? 345 ALA A O   1 
ATOM   2592 C CB  . ALA A 1 346 ? -16.19116 -12.63116 23.45765  1.000 34.12209  ? 345 ALA A CB  1 
ATOM   2593 N N   . ALA A 1 347 ? -17.17457 -10.02416 21.75337  1.000 38.24452  ? 346 ALA A N   1 
ATOM   2594 C CA  . ALA A 1 347 ? -17.05518 -9.25172  20.52591  1.000 38.36526  ? 346 ALA A CA  1 
ATOM   2595 C C   . ALA A 1 347 ? -15.79064 -8.40348  20.57317  1.000 45.42139  ? 346 ALA A C   1 
ATOM   2596 O O   . ALA A 1 347 ? -15.29535 -8.04581  21.64781  1.000 44.99552  ? 346 ALA A O   1 
ATOM   2597 C CB  . ALA A 1 347 ? -18.26005 -8.34205  20.30555  1.000 36.94168  ? 346 ALA A CB  1 
ATOM   2598 N N   . ILE A 1 348 ? -15.27247 -8.07950  19.39343  1.000 41.73923  ? 347 ILE A N   1 
ATOM   2599 C CA  . ILE A 1 348 ? -14.05098 -7.30084  19.26060  1.000 35.22753  ? 347 ILE A CA  1 
ATOM   2600 C C   . ILE A 1 348 ? -14.21844 -6.42225  18.03117  1.000 38.54871  ? 347 ILE A C   1 
ATOM   2601 O O   . ILE A 1 348 ? -14.83586 -6.83152  17.04305  1.000 41.56554  ? 347 ILE A O   1 
ATOM   2602 C CB  . ILE A 1 348 ? -12.81337 -8.22885  19.20573  1.000 37.94389  ? 347 ILE A CB  1 
ATOM   2603 C CG1 . ILE A 1 348 ? -11.51189 -7.44936  19.34561  1.000 40.26273  ? 347 ILE A CG1 1 
ATOM   2604 C CG2 . ILE A 1 348 ? -12.81270 -9.10040  17.97634  1.000 35.24791  ? 347 ILE A CG2 1 
ATOM   2605 C CD1 . ILE A 1 348 ? -10.29968 -8.32541  19.66850  1.000 32.73566  ? 347 ILE A CD1 1 
ATOM   2606 N N   . GLY A 1 349 ? -13.74313 -5.18682  18.12208  1.000 41.88266  ? 348 GLY A N   1 
ATOM   2607 C CA  . GLY A 1 349 ? -13.98899 -4.19946  17.08900  1.000 40.32041  ? 348 GLY A CA  1 
ATOM   2608 C C   . GLY A 1 349 ? -12.85882 -3.20019  16.97594  1.000 42.34435  ? 348 GLY A C   1 
ATOM   2609 O O   . GLY A 1 349 ? -12.36615 -2.70563  17.99015  1.000 40.61163  ? 348 GLY A O   1 
ATOM   2610 N N   . TYR A 1 350 ? -12.42645 -2.90738  15.75185  1.000 47.20296  ? 349 TYR A N   1 
ATOM   2611 C CA  . TYR A 1 350 ? -11.32457 -1.98545  15.49887  1.000 45.26224  ? 349 TYR A CA  1 
ATOM   2612 C C   . TYR A 1 350 ? -11.88883 -0.62915  15.09913  1.000 43.88235  ? 349 TYR A C   1 
ATOM   2613 O O   . TYR A 1 350 ? -12.81114 -0.55152  14.28042  1.000 41.31113  ? 349 TYR A O   1 
ATOM   2614 C CB  . TYR A 1 350 ? -10.40041 -2.53374  14.40849  1.000 43.96775  ? 349 TYR A CB  1 
ATOM   2615 C CG  . TYR A 1 350 ? -9.17602  -1.68974  14.12065  1.000 49.39296  ? 349 TYR A CG  1 
ATOM   2616 C CD1 . TYR A 1 350 ? -7.99584  -1.87003  14.83876  1.000 51.08411  ? 349 TYR A CD1 1 
ATOM   2617 C CD2 . TYR A 1 350 ? -9.19115  -0.72202  13.11213  1.000 54.58481  ? 349 TYR A CD2 1 
ATOM   2618 C CE1 . TYR A 1 350 ? -6.86284  -1.09940  14.57646  1.000 52.89819  ? 349 TYR A CE1 1 
ATOM   2619 C CE2 . TYR A 1 350 ? -8.06624  0.06218   12.84157  1.000 55.29781  ? 349 TYR A CE2 1 
ATOM   2620 C CZ  . TYR A 1 350 ? -6.90419  -0.13267  13.57804  1.000 57.06605  ? 349 TYR A CZ  1 
ATOM   2621 O OH  . TYR A 1 350 ? -5.78568  0.63093   13.31452  1.000 57.29122  ? 349 TYR A OH  1 
ATOM   2622 N N   . ARG A 1 351 ? -11.36997 0.42957   15.71515  1.000 51.11753  ? 350 ARG A N   1 
ATOM   2623 C CA  . ARG A 1 351 ? -11.74279 1.80210   15.38909  1.000 52.45769  ? 350 ARG A CA  1 
ATOM   2624 C C   . ARG A 1 351 ? -10.53923 2.49397   14.77199  1.000 56.70613  ? 350 ARG A C   1 
ATOM   2625 O O   . ARG A 1 351 ? -9.41930  2.39840   15.28934  1.000 58.21906  ? 350 ARG A O   1 
ATOM   2626 C CB  . ARG A 1 351 ? -12.23050 2.60076   16.61295  1.000 44.50233  ? 350 ARG A CB  1 
ATOM   2627 C CG  . ARG A 1 351 ? -12.85222 1.79458   17.73670  1.000 52.09372  ? 350 ARG A CG  1 
ATOM   2628 C CD  . ARG A 1 351 ? -13.17862 2.64834   18.97175  1.000 63.30125  ? 350 ARG A CD  1 
ATOM   2629 N NE  . ARG A 1 351 ? -12.09502 3.54820   19.37603  1.000 71.17877  ? 350 ARG A NE  1 
ATOM   2630 C CZ  . ARG A 1 351 ? -11.18436 3.29714   20.31591  1.000 69.62334  ? 350 ARG A CZ  1 
ATOM   2631 N NH1 . ARG A 1 351 ? -11.12929 2.12608   20.94193  1.000 62.14073  ? 350 ARG A NH1 1 
ATOM   2632 N NH2 . ARG A 1 351 ? -10.29732 4.24411   20.62954  1.000 65.79464  ? 350 ARG A NH2 1 
ATOM   2633 N N   . ASN A 1 352 ? -10.77045 3.18945   13.67433  1.000 53.51285  ? 351 ASN A N   1 
ATOM   2634 C CA  . ASN A 1 352 ? -9.72392  3.93064   12.99740  1.000 52.30761  ? 351 ASN A CA  1 
ATOM   2635 C C   . ASN A 1 352 ? -9.93629  5.41192   13.27350  1.000 55.59821  ? 351 ASN A C   1 
ATOM   2636 O O   . ASN A 1 352 ? -11.02345 5.94336   13.01939  1.000 54.64274  ? 351 ASN A O   1 
ATOM   2637 C CB  . ASN A 1 352 ? -9.75557  3.62828   11.50820  1.000 55.72488  ? 351 ASN A CB  1 
ATOM   2638 C CG  . ASN A 1 352 ? -8.76064  4.42450   10.75292  1.000 59.60245  ? 351 ASN A CG  1 
ATOM   2639 O OD1 . ASN A 1 352 ? -8.99684  5.59693   10.45751  1.000 59.43964  ? 351 ASN A OD1 1 
ATOM   2640 N ND2 . ASN A 1 352 ? -7.62776  3.80593   10.42559  1.000 60.52182  ? 351 ASN A ND2 1 
ATOM   2641 N N   . THR A 1 353 ? -8.91005  6.06598   13.82151  1.000 60.93364  ? 352 THR A N   1 
ATOM   2642 C CA  . THR A 1 353 ? -9.04897  7.45540   14.25566  1.000 61.60689  ? 352 THR A CA  1 
ATOM   2643 C C   . THR A 1 353 ? -9.48351  8.34902   13.10221  1.000 60.89465  ? 352 THR A C   1 
ATOM   2644 O O   . THR A 1 353 ? -10.51020 9.03542   13.17582  1.000 61.22351  ? 352 THR A O   1 
ATOM   2645 C CB  . THR A 1 353 ? -7.72647  7.95450   14.83828  1.000 61.40309  ? 352 THR A CB  1 
ATOM   2646 O OG1 . THR A 1 353 ? -7.53822  7.39016   16.14083  1.000 65.61728  ? 352 THR A OG1 1 
ATOM   2647 C CG2 . THR A 1 353 ? -7.71980  9.48294   14.92029  1.000 54.63751  ? 352 THR A CG2 1 
ATOM   2648 N N   . THR A 1 354 ? -8.70595  8.33765   12.01627  1.000 60.72674  ? 353 THR A N   1 
ATOM   2649 C CA  . THR A 1 354 ? -8.97715  9.21186   10.88034  1.000 58.20015  ? 353 THR A CA  1 
ATOM   2650 C C   . THR A 1 354 ? -10.32100 8.89381   10.23751  1.000 58.28448  ? 353 THR A C   1 
ATOM   2651 O O   . THR A 1 354 ? -11.04099 9.80213   9.79903   1.000 56.13667  ? 353 THR A O   1 
ATOM   2652 C CB  . THR A 1 354 ? -7.85180  9.07606   9.86150   1.000 52.50190  ? 353 THR A CB  1 
ATOM   2653 O OG1 . THR A 1 354 ? -6.58826  9.17613   10.53499  1.000 60.97178  ? 353 THR A OG1 1 
ATOM   2654 C CG2 . THR A 1 354 ? -7.95915  10.15589  8.82884   1.000 45.42371  ? 353 THR A CG2 1 
ATOM   2655 N N   . LEU A 1 355 ? -10.68008 7.60637   10.18627  1.000 54.82565  ? 354 LEU A N   1 
ATOM   2656 C CA  . LEU A 1 355 ? -11.91826 7.19489   9.53913   1.000 53.11715  ? 354 LEU A CA  1 
ATOM   2657 C C   . LEU A 1 355 ? -13.13093 7.43964   10.42158  1.000 54.13657  ? 354 LEU A C   1 
ATOM   2658 O O   . LEU A 1 355 ? -14.19807 7.80169   9.92053   1.000 54.67016  ? 354 LEU A O   1 
ATOM   2659 C CB  . LEU A 1 355 ? -11.83839 5.72545   9.14758   1.000 55.00197  ? 354 LEU A CB  1 
ATOM   2660 C CG  . LEU A 1 355 ? -11.66037 5.57528   7.63945   1.000 56.62111  ? 354 LEU A CG  1 
ATOM   2661 C CD1 . LEU A 1 355 ? -11.19298 4.16911   7.24672   1.000 47.64417  ? 354 LEU A CD1 1 
ATOM   2662 C CD2 . LEU A 1 355 ? -12.96590 5.95473   6.97790   1.000 50.56401  ? 354 LEU A CD2 1 
ATOM   2663 N N   . THR A 1 356 ? -12.99810 7.22535   11.73036  1.000 58.40537  ? 355 THR A N   1 
ATOM   2664 C CA  . THR A 1 356 ? -14.09568 7.55599   12.62673  1.000 60.55002  ? 355 THR A CA  1 
ATOM   2665 C C   . THR A 1 356 ? -14.32607 9.05251   12.65421  1.000 60.56497  ? 355 THR A C   1 
ATOM   2666 O O   . THR A 1 356 ? -15.47136 9.50540   12.77882  1.000 66.79669  ? 355 THR A O   1 
ATOM   2667 C CB  . THR A 1 356 ? -13.80795 7.02558   14.02717  1.000 60.50309  ? 355 THR A CB  1 
ATOM   2668 O OG1 . THR A 1 356 ? -13.69433 5.59829   13.96198  1.000 63.51343  ? 355 THR A OG1 1 
ATOM   2669 C CG2 . THR A 1 356 ? -14.92894 7.39703   14.97702  1.000 55.45978  ? 355 THR A CG2 1 
ATOM   2670 N N   . ALA A 1 357 ? -13.24711 9.82085   12.49849  1.000 60.99640  ? 356 ALA A N   1 
ATOM   2671 C CA  . ALA A 1 357 ? -13.33577 11.27478  12.43551  1.000 62.73624  ? 356 ALA A CA  1 
ATOM   2672 C C   . ALA A 1 357 ? -14.28947 11.73567  11.33887  1.000 59.94882  ? 356 ALA A C   1 
ATOM   2673 O O   . ALA A 1 357 ? -15.24023 12.48277  11.60139  1.000 59.75666  ? 356 ALA A O   1 
ATOM   2674 C CB  . ALA A 1 357 ? -11.94075 11.85724  12.21054  1.000 60.91054  ? 356 ALA A CB  1 
ATOM   2675 N N   . ILE A 1 358 ? -14.06043 11.28497  10.10585  1.000 56.41556  ? 357 ILE A N   1 
ATOM   2676 C CA  . ILE A 1 358 ? -14.72651 11.85463  8.93977   1.000 58.90779  ? 357 ILE A CA  1 
ATOM   2677 C C   . ILE A 1 358 ? -16.03808 11.15927  8.58652   1.000 62.29360  ? 357 ILE A C   1 
ATOM   2678 O O   . ILE A 1 358 ? -16.54112 11.32531  7.46590   1.000 66.42172  ? 357 ILE A O   1 
ATOM   2679 C CB  . ILE A 1 358 ? -13.77872 11.84482  7.72258   1.000 61.33902  ? 357 ILE A CB  1 
ATOM   2680 C CG1 . ILE A 1 358 ? -13.36093 10.41945  7.36541   1.000 56.03092  ? 357 ILE A CG1 1 
ATOM   2681 C CG2 . ILE A 1 358 ? -12.55109 12.70481  7.96940   1.000 65.27750  ? 357 ILE A CG2 1 
ATOM   2682 C CD1 . ILE A 1 358 ? -12.66220 10.34365  6.03590   1.000 59.06007  ? 357 ILE A CD1 1 
ATOM   2683 N N   . THR A 1 359 ? -16.61719 10.39684  9.52168   1.000 58.75155  ? 358 THR A N   1 
ATOM   2684 C CA  . THR A 1 359 ? -17.81499 9.62091   9.21203   1.000 59.64824  ? 358 THR A CA  1 
ATOM   2685 C C   . THR A 1 359 ? -18.85111 9.73173   10.31863  1.000 66.83789  ? 358 THR A C   1 
ATOM   2686 O O   . THR A 1 359 ? -18.51340 9.71998   11.51041  1.000 61.70124  ? 358 THR A O   1 
ATOM   2687 C CB  . THR A 1 359 ? -17.50819 8.13185   8.99332   1.000 58.56568  ? 358 THR A CB  1 
ATOM   2688 O OG1 . THR A 1 359 ? -16.80286 7.60887   10.12736  1.000 59.85553  ? 358 THR A OG1 1 
ATOM   2689 C CG2 . THR A 1 359 ? -16.68095 7.93055   7.73177   1.000 54.89033  ? 358 THR A CG2 1 
ATOM   2690 N N   . ARG A 1 360 ? -20.12042 9.81987   9.90152   1.000 66.20136  ? 359 ARG A N   1 
ATOM   2691 C CA  . ARG A 1 360 ? -21.25537 9.75233   10.80607  1.000 67.91471  ? 359 ARG A CA  1 
ATOM   2692 C C   . ARG A 1 360 ? -21.51312 8.30267   11.18950  1.000 67.68732  ? 359 ARG A C   1 
ATOM   2693 O O   . ARG A 1 360 ? -21.05716 7.38082   10.51071  1.000 63.99091  ? 359 ARG A O   1 
ATOM   2694 C CB  . ARG A 1 360 ? -22.50267 10.35286  10.15695  1.000 62.44125  ? 359 ARG A CB  1 
ATOM   2695 N N   . PRO A 1 361 ? -22.21369 8.07476   12.29734  1.000 74.22655  ? 360 PRO A N   1 
ATOM   2696 C CA  . PRO A 1 361 ? -22.54725 6.69961   12.69102  1.000 67.59564  ? 360 PRO A CA  1 
ATOM   2697 C C   . PRO A 1 361 ? -23.34275 5.97063   11.61626  1.000 67.37334  ? 360 PRO A C   1 
ATOM   2698 O O   . PRO A 1 361 ? -24.14933 6.56035   10.89067  1.000 70.26685  ? 360 PRO A O   1 
ATOM   2699 C CB  . PRO A 1 361 ? -23.37891 6.89008   13.96089  1.000 63.02515  ? 360 PRO A CB  1 
ATOM   2700 C CG  . PRO A 1 361 ? -22.90392 8.19107   14.51742  1.000 70.20003  ? 360 PRO A CG  1 
ATOM   2701 C CD  . PRO A 1 361 ? -22.51886 9.05252   13.35693  1.000 73.82590  ? 360 PRO A CD  1 
ATOM   2702 N N   . GLY A 1 362 ? -23.11339 4.66283   11.53062  1.000 61.20958  ? 361 GLY A N   1 
ATOM   2703 C CA  . GLY A 1 362 ? -23.72735 3.84801   10.51364  1.000 55.00548  ? 361 GLY A CA  1 
ATOM   2704 C C   . GLY A 1 362 ? -22.93732 3.73128   9.23194   1.000 58.39705  ? 361 GLY A C   1 
ATOM   2705 O O   . GLY A 1 362 ? -23.33096 2.95473   8.35386   1.000 64.02997  ? 361 GLY A O   1 
ATOM   2706 N N   . SER A 1 363 ? -21.83824 4.46905   9.09642   1.000 54.45490  ? 362 SER A N   1 
ATOM   2707 C CA  . SER A 1 363 ? -21.04053 4.41228   7.88068   1.000 54.70452  ? 362 SER A CA  1 
ATOM   2708 C C   . SER A 1 363 ? -20.43766 3.02583   7.69905   1.000 55.53182  ? 362 SER A C   1 
ATOM   2709 O O   . SER A 1 363 ? -20.00171 2.39435   8.66369   1.000 55.61008  ? 362 SER A O   1 
ATOM   2710 C CB  . SER A 1 363 ? -19.92838 5.46194   7.93398   1.000 57.90446  ? 362 SER A CB  1 
ATOM   2711 O OG  . SER A 1 363 ? -18.99822 5.30614   6.86895   1.000 56.26559  ? 362 SER A OG  1 
ATOM   2712 N N   . GLU A 1 364 ? -20.41462 2.54966   6.44727   1.000 52.32790  ? 363 GLU A N   1 
ATOM   2713 C CA  . GLU A 1 364 ? -19.76566 1.27426   6.15591   1.000 49.20297  ? 363 GLU A CA  1 
ATOM   2714 C C   . GLU A 1 364 ? -18.27303 1.30798   6.39670   1.000 48.86367  ? 363 GLU A C   1 
ATOM   2715 O O   . GLU A 1 364 ? -17.64737 0.24292   6.45491   1.000 48.98443  ? 363 GLU A O   1 
ATOM   2716 C CB  . GLU A 1 364 ? -19.99476 0.82412   4.71678   1.000 53.48286  ? 363 GLU A CB  1 
ATOM   2717 C CG  . GLU A 1 364 ? -21.19341 -0.06734  4.51937   1.000 62.74120  ? 363 GLU A CG  1 
ATOM   2718 C CD  . GLU A 1 364 ? -22.48721 0.56911   4.94247   1.000 68.43987  ? 363 GLU A CD  1 
ATOM   2719 O OE1 . GLU A 1 364 ? -22.59721 1.81654   4.85409   1.000 75.80559  ? 363 GLU A OE1 1 
ATOM   2720 O OE2 . GLU A 1 364 ? -23.38352 -0.18727  5.38467   1.000 67.00573  ? 363 GLU A OE2 1 
ATOM   2721 N N   . TYR A 1 365 ? -17.67718 2.49319   6.49927   1.000 45.72804  ? 364 TYR A N   1 
ATOM   2722 C CA  . TYR A 1 365 ? -16.27231 2.54168   6.86494   1.000 49.34515  ? 364 TYR A CA  1 
ATOM   2723 C C   . TYR A 1 365 ? -16.06007 2.21696   8.34319   1.000 54.26569  ? 364 TYR A C   1 
ATOM   2724 O O   . TYR A 1 365 ? -14.91924 1.97929   8.76725   1.000 52.75862  ? 364 TYR A O   1 
ATOM   2725 C CB  . TYR A 1 365 ? -15.71285 3.90934   6.48236   1.000 45.62227  ? 364 TYR A CB  1 
ATOM   2726 C CG  . TYR A 1 365 ? -15.63576 4.10361   4.98027   1.000 47.05278  ? 364 TYR A CG  1 
ATOM   2727 C CD1 . TYR A 1 365 ? -14.59172 3.55434   4.24546   1.000 45.85453  ? 364 TYR A CD1 1 
ATOM   2728 C CD2 . TYR A 1 365 ? -16.60652 4.82523   4.29551   1.000 44.70416  ? 364 TYR A CD2 1 
ATOM   2729 C CE1 . TYR A 1 365 ? -14.51796 3.71765   2.86912   1.000 47.61437  ? 364 TYR A CE1 1 
ATOM   2730 C CE2 . TYR A 1 365 ? -16.53949 5.00029   2.92097   1.000 46.33236  ? 364 TYR A CE2 1 
ATOM   2731 C CZ  . TYR A 1 365 ? -15.49341 4.44289   2.20500   1.000 50.03687  ? 364 TYR A CZ  1 
ATOM   2732 O OH  . TYR A 1 365 ? -15.40959 4.60805   0.82654   1.000 46.27174  ? 364 TYR A OH  1 
ATOM   2733 N N   . ARG A 1 366 ? -17.13618 2.16396   9.12464   1.000 52.35420  ? 365 ARG A N   1 
ATOM   2734 C CA  . ARG A 1 366 ? -17.07401 1.73623   10.50946  1.000 53.01500  ? 365 ARG A CA  1 
ATOM   2735 C C   . ARG A 1 366 ? -17.48815 0.28573   10.70936  1.000 52.92300  ? 365 ARG A C   1 
ATOM   2736 O O   . ARG A 1 366 ? -17.45156 -0.18959  11.84739  1.000 53.90558  ? 365 ARG A O   1 
ATOM   2737 C CB  . ARG A 1 366 ? -17.95134 2.63749   11.37358  1.000 52.91105  ? 365 ARG A CB  1 
ATOM   2738 C CG  . ARG A 1 366 ? -17.60547 4.07523   11.21048  1.000 53.85660  ? 365 ARG A CG  1 
ATOM   2739 C CD  . ARG A 1 366 ? -17.67800 4.77872   12.52958  1.000 69.12123  ? 365 ARG A CD  1 
ATOM   2740 N NE  . ARG A 1 366 ? -18.53902 5.94956   12.50455  1.000 76.05137  ? 365 ARG A NE  1 
ATOM   2741 C CZ  . ARG A 1 366 ? -18.71931 6.74339   13.54969  1.000 71.61968  ? 365 ARG A CZ  1 
ATOM   2742 N NH1 . ARG A 1 366 ? -18.12748 6.49622   14.71016  1.000 65.14506  ? 365 ARG A NH1 1 
ATOM   2743 N NH2 . ARG A 1 366 ? -19.49216 7.82040   13.42077  1.000 64.60243  ? 365 ARG A NH2 1 
ATOM   2744 N N   . LYS A 1 367 ? -17.87918 -0.43004  9.64528   1.000 47.28397  ? 366 LYS A N   1 
ATOM   2745 C CA  . LYS A 1 367 ? -18.30690 -1.82346  9.75104   1.000 47.71379  ? 366 LYS A CA  1 
ATOM   2746 C C   . LYS A 1 367 ? -17.32656 -2.81243  9.10415   1.000 47.54898  ? 366 LYS A C   1 
ATOM   2747 O O   . LYS A 1 367 ? -17.72922 -3.91136  8.70738   1.000 48.69948  ? 366 LYS A O   1 
ATOM   2748 C CB  . LYS A 1 367 ? -19.70046 -2.01451  9.15071   1.000 43.46333  ? 366 LYS A CB  1 
ATOM   2749 C CG  . LYS A 1 367 ? -20.74372 -0.99552  9.56258   1.000 48.46310  ? 366 LYS A CG  1 
ATOM   2750 C CD  . LYS A 1 367 ? -22.06158 -1.21811  8.79320   1.000 52.90333  ? 366 LYS A CD  1 
ATOM   2751 C CE  . LYS A 1 367 ? -23.27841 -0.57182  9.47682   1.000 54.39432  ? 366 LYS A CE  1 
ATOM   2752 N NZ  . LYS A 1 367 ? -24.26738 -1.56068  10.01625  1.000 55.50062  ? 366 LYS A NZ  1 
ATOM   2753 N N   . LEU A 1 368 ? -16.03676 -2.47052  9.02526   1.000 40.68722  ? 367 LEU A N   1 
ATOM   2754 C CA  . LEU A 1 368 ? -15.10363 -3.31679  8.28770   1.000 36.08943  ? 367 LEU A CA  1 
ATOM   2755 C C   . LEU A 1 368 ? -14.42450 -4.37119  9.15754   1.000 38.05675  ? 367 LEU A C   1 
ATOM   2756 O O   . LEU A 1 368 ? -14.46197 -5.55229  8.81726   1.000 35.87515  ? 367 LEU A O   1 
ATOM   2757 C CB  . LEU A 1 368 ? -14.04616 -2.45366  7.60407   1.000 36.48130  ? 367 LEU A CB  1 
ATOM   2758 C CG  . LEU A 1 368 ? -14.59827 -1.36945  6.67916   1.000 40.97087  ? 367 LEU A CG  1 
ATOM   2759 C CD1 . LEU A 1 368 ? -13.44721 -0.56221  6.17551   1.000 33.66024  ? 367 LEU A CD1 1 
ATOM   2760 C CD2 . LEU A 1 368 ? -15.44689 -1.93251  5.51850   1.000 35.89105  ? 367 LEU A CD2 1 
ATOM   2761 N N   . LEU A 1 369 ? -13.78746 -3.97140  10.26400  1.000 42.86797  ? 368 LEU A N   1 
ATOM   2762 C CA  . LEU A 1 369 ? -12.95885 -4.86644  11.08973  1.000 43.13524  ? 368 LEU A CA  1 
ATOM   2763 C C   . LEU A 1 369 ? -13.65227 -5.07786  12.43747  1.000 45.69118  ? 368 LEU A C   1 
ATOM   2764 O O   . LEU A 1 369 ? -13.50593 -4.27750  13.36378  1.000 45.82921  ? 368 LEU A O   1 
ATOM   2765 C CB  . LEU A 1 369 ? -11.54262 -4.31019  11.27289  1.000 42.73027  ? 368 LEU A CB  1 
ATOM   2766 C CG  . LEU A 1 369 ? -10.36206 -5.17657  11.74350  1.000 38.24992  ? 368 LEU A CG  1 
ATOM   2767 C CD1 . LEU A 1 369 ? -10.30647 -6.54991  11.13415  1.000 33.19957  ? 368 LEU A CD1 1 
ATOM   2768 C CD2 . LEU A 1 369 ? -9.09018  -4.44332  11.40788  1.000 41.26208  ? 368 LEU A CD2 1 
ATOM   2769 N N   . SER A 1 370 ? -14.41045 -6.17446  12.52254  1.000 45.14493  ? 369 SER A N   1 
ATOM   2770 C CA  . SER A 1 370 ? -15.16627 -6.59741  13.69016  1.000 36.76363  ? 369 SER A CA  1 
ATOM   2771 C C   . SER A 1 370 ? -15.29880 -8.10944  13.62968  1.000 45.26640  ? 369 SER A C   1 
ATOM   2772 O O   . SER A 1 370 ? -15.11144 -8.72513  12.57475  1.000 45.45565  ? 369 SER A O   1 
ATOM   2773 C CB  . SER A 1 370 ? -16.55641 -5.96220  13.74343  1.000 38.91513  ? 369 SER A CB  1 
ATOM   2774 O OG  . SER A 1 370 ? -16.47165 -4.55450  13.73973  1.000 46.28388  ? 369 SER A OG  1 
ATOM   2775 N N   . ALA A 1 371 ? -15.62976 -8.70108  14.77624  1.000 44.14551  ? 370 ALA A N   1 
ATOM   2776 C CA  . ALA A 1 371 ? -15.80220 -10.14201 14.92451  1.000 35.63513  ? 370 ALA A CA  1 
ATOM   2777 C C   . ALA A 1 371 ? -16.44597 -10.39376 16.28002  1.000 40.67529  ? 370 ALA A C   1 
ATOM   2778 O O   . ALA A 1 371 ? -16.24685 -9.61258  17.21921  1.000 41.74159  ? 370 ALA A O   1 
ATOM   2779 C CB  . ALA A 1 371 ? -14.46610 -10.89256 14.81095  1.000 27.48164  ? 370 ALA A CB  1 
ATOM   2780 N N   . LEU A 1 372 ? -17.24867 -11.45812 16.36896  1.000 35.55934  ? 371 LEU A N   1 
ATOM   2781 C CA  . LEU A 1 372 ? -17.76294 -11.86333 17.66636  1.000 33.82394  ? 371 LEU A CA  1 
ATOM   2782 C C   . LEU A 1 372 ? -17.90668 -13.37141 17.69060  1.000 35.75142  ? 371 LEU A C   1 
ATOM   2783 O O   . LEU A 1 372 ? -18.24009 -13.98635 16.67803  1.000 40.72575  ? 371 LEU A O   1 
ATOM   2784 C CB  . LEU A 1 372 ? -19.12790 -11.27068 18.02145  1.000 34.77327  ? 371 LEU A CB  1 
ATOM   2785 C CG  . LEU A 1 372 ? -20.30468 -11.52742 17.10799  1.000 34.13543  ? 371 LEU A CG  1 
ATOM   2786 C CD1 . LEU A 1 372 ? -21.00227 -12.74385 17.64350  1.000 35.53101  ? 371 LEU A CD1 1 
ATOM   2787 C CD2 . LEU A 1 372 ? -21.25952 -10.37603 17.20684  1.000 32.65970  ? 371 LEU A CD2 1 
ATOM   2788 N N   . TRP A 1 373 ? -17.71534 -13.95445 18.87242  1.000 36.70333  ? 372 TRP A N   1 
ATOM   2789 C CA  . TRP A 1 373 ? -17.80836 -15.39155 19.07329  1.000 33.63506  ? 372 TRP A CA  1 
ATOM   2790 C C   . TRP A 1 373 ? -19.17318 -15.76416 19.62489  1.000 35.08352  ? 372 TRP A C   1 
ATOM   2791 O O   . TRP A 1 373 ? -19.77948 -15.00460 20.37949  1.000 41.04199  ? 372 TRP A O   1 
ATOM   2792 C CB  . TRP A 1 373 ? -16.73978 -15.86547 20.04095  1.000 35.48023  ? 372 TRP A CB  1 
ATOM   2793 C CG  . TRP A 1 373 ? -15.37423 -15.77291 19.52847  1.000 31.56973  ? 372 TRP A CG  1 
ATOM   2794 C CD1 . TRP A 1 373 ? -14.64358 -16.77809 18.98421  1.000 34.57100  ? 372 TRP A CD1 1 
ATOM   2795 C CD2 . TRP A 1 373 ? -14.54024 -14.61842 19.52605  1.000 26.49322  ? 372 TRP A CD2 1 
ATOM   2796 N NE1 . TRP A 1 373 ? -13.39766 -16.32107 18.63277  1.000 33.03971  ? 372 TRP A NE1 1 
ATOM   2797 C CE2 . TRP A 1 373 ? -13.30870 -14.99500 18.95599  1.000 27.11751  ? 372 TRP A CE2 1 
ATOM   2798 C CE3 . TRP A 1 373 ? -14.71433 -13.30324 19.93990  1.000 30.49295  ? 372 TRP A CE3 1 
ATOM   2799 C CZ2 . TRP A 1 373 ? -12.25390 -14.10742 18.79910  1.000 26.81372  ? 372 TRP A CZ2 1 
ATOM   2800 C CZ3 . TRP A 1 373 ? -13.65787 -12.41101 19.77803  1.000 34.86005  ? 372 TRP A CZ3 1 
ATOM   2801 C CH2 . TRP A 1 373 ? -12.44785 -12.81918 19.21698  1.000 31.38942  ? 372 TRP A CH2 1 
ATOM   2802 N N   . ARG A 1 374 ? -19.64320 -16.95295 19.26415  1.000 34.42945  ? 373 ARG A N   1 
ATOM   2803 C CA  . ARG A 1 374 ? -20.94319 -17.40945 19.71938  1.000 34.64466  ? 373 ARG A CA  1 
ATOM   2804 C C   . ARG A 1 374 ? -20.85007 -18.87418 20.10675  1.000 40.75949  ? 373 ARG A C   1 
ATOM   2805 O O   . ARG A 1 374 ? -20.12241 -19.64269 19.47014  1.000 41.34081  ? 373 ARG A O   1 
ATOM   2806 C CB  . ARG A 1 374 ? -22.02470 -17.22430 18.65685  1.000 33.62538  ? 373 ARG A CB  1 
ATOM   2807 C CG  . ARG A 1 374 ? -23.32540 -17.89821 19.05148  1.000 39.51753  ? 373 ARG A CG  1 
ATOM   2808 C CD  . ARG A 1 374 ? -24.31198 -17.89702 17.95203  1.000 38.82701  ? 373 ARG A CD  1 
ATOM   2809 N NE  . ARG A 1 374 ? -24.80432 -16.55915 17.67430  1.000 39.21037  ? 373 ARG A NE  1 
ATOM   2810 C CZ  . ARG A 1 374 ? -25.09196 -16.11811 16.45730  1.000 43.97205  ? 373 ARG A CZ  1 
ATOM   2811 N NH1 . ARG A 1 374 ? -24.84494 -16.85147 15.38011  1.000 39.05302  ? 373 ARG A NH1 1 
ATOM   2812 N NH2 . ARG A 1 374 ? -25.64669 -14.91491 16.31792  1.000 46.24743  ? 373 ARG A NH2 1 
ATOM   2813 N N   . GLU A 1 375 ? -21.58917 -19.24233 21.15960  1.000 42.20012  ? 374 GLU A N   1 
ATOM   2814 C CA  . GLU A 1 375 ? -21.59947 -20.60885 21.66972  1.000 39.29778  ? 374 GLU A CA  1 
ATOM   2815 C C   . GLU A 1 375 ? -22.01795 -21.59602 20.59620  1.000 37.08283  ? 374 GLU A C   1 
ATOM   2816 O O   . GLU A 1 375 ? -23.02047 -21.38448 19.91360  1.000 40.18285  ? 374 GLU A O   1 
ATOM   2817 C CB  . GLU A 1 375 ? -22.57988 -20.72984 22.82886  1.000 40.45828  ? 374 GLU A CB  1 
ATOM   2818 C CG  . GLU A 1 375 ? -22.14390 -20.12846 24.11365  1.000 39.31848  ? 374 GLU A CG  1 
ATOM   2819 C CD  . GLU A 1 375 ? -23.26077 -20.13318 25.11959  1.000 43.83432  ? 374 GLU A CD  1 
ATOM   2820 O OE1 . GLU A 1 375 ? -24.30915 -19.47600 24.88072  1.000 44.90730  ? 374 GLU A OE1 1 
ATOM   2821 O OE2 . GLU A 1 375 ? -23.09156 -20.81795 26.14618  1.000 53.19186  ? 374 GLU A OE2 1 
ATOM   2822 N N   . SER A 1 376 ? -21.24611 -22.72918 20.47049  1.000 37.91801  ? 375 SER A N   1 
ATOM   2823 C CA  . SER A 1 376 ? -21.89151 -23.70900 19.61816  1.000 39.74469  ? 375 SER A CA  1 
ATOM   2824 C C   . SER A 1 376 ? -22.81281 -24.60629 20.44230  1.000 43.49199  ? 375 SER A C   1 
ATOM   2825 O O   . SER A 1 376 ? -22.56665 -24.84186 21.62932  1.000 42.36549  ? 375 SER A O   1 
ATOM   2826 C CB  . SER A 1 376 ? -20.85699 -24.56581 18.91190  1.000 36.98251  ? 375 SER A CB  1 
ATOM   2827 O OG  . SER A 1 376 ? -20.74952 -25.81584 19.54381  1.000 43.09347  ? 375 SER A OG  1 
ATOM   2828 N N   . PRO A 1 377 ? -23.87144 -25.15832 19.84798  1.000 43.98726  ? 376 PRO A N   1 
ATOM   2829 C CA  . PRO A 1 377 ? -24.82209 -25.95426 20.63116  1.000 40.29267  ? 376 PRO A CA  1 
ATOM   2830 C C   . PRO A 1 377 ? -24.39223 -27.39196 20.88138  1.000 44.47605  ? 376 PRO A C   1 
ATOM   2831 O O   . PRO A 1 377 ? -25.08506 -28.10123 21.61384  1.000 50.28189  ? 376 PRO A O   1 
ATOM   2832 C CB  . PRO A 1 377 ? -26.07655 -25.91796 19.75763  1.000 35.99864  ? 376 PRO A CB  1 
ATOM   2833 C CG  . PRO A 1 377 ? -25.53260 -25.89492 18.36517  1.000 41.50887  ? 376 PRO A CG  1 
ATOM   2834 C CD  . PRO A 1 377 ? -24.23999 -25.10549 18.42176  1.000 40.78217  ? 376 PRO A CD  1 
ATOM   2835 N N   . VAL A 1 378 ? -23.27005 -27.84590 20.32588  1.000 44.78197  ? 377 VAL A N   1 
ATOM   2836 C CA  . VAL A 1 378 ? -23.05569 -29.28148 20.15015  1.000 40.79220  ? 377 VAL A CA  1 
ATOM   2837 C C   . VAL A 1 378 ? -22.93235 -30.01238 21.48630  1.000 38.33182  ? 377 VAL A C   1 
ATOM   2838 O O   . VAL A 1 378 ? -23.35695 -31.16771 21.61575  1.000 38.79260  ? 377 VAL A O   1 
ATOM   2839 C CB  . VAL A 1 378 ? -21.82901 -29.51602 19.25687  1.000 38.93389  ? 377 VAL A CB  1 
ATOM   2840 C CG1 . VAL A 1 378 ? -21.60704 -31.00560 19.07803  1.000 32.68801  ? 377 VAL A CG1 1 
ATOM   2841 C CG2 . VAL A 1 378 ? -22.02344 -28.79022 17.91315  1.000 37.23269  ? 377 VAL A CG2 1 
ATOM   2842 N N   . SER A 1 379 ? -22.33921 -29.37421 22.49507  1.000 44.79543  ? 378 SER A N   1 
ATOM   2843 C CA  . SER A 1 379 ? -22.14398 -30.07092 23.77019  1.000 45.94470  ? 378 SER A CA  1 
ATOM   2844 C C   . SER A 1 379 ? -23.46305 -30.32495 24.49415  1.000 46.99139  ? 378 SER A C   1 
ATOM   2845 O O   . SER A 1 379 ? -23.57683 -31.28253 25.26652  1.000 47.52629  ? 378 SER A O   1 
ATOM   2846 C CB  . SER A 1 379 ? -21.23928 -29.26341 24.67854  1.000 47.59791  ? 378 SER A CB  1 
ATOM   2847 O OG  . SER A 1 379 ? -22.04622 -28.33678 25.39490  1.000 57.87772  ? 378 SER A OG  1 
ATOM   2848 N N   . ARG A 1 380 ? -24.45366 -29.48062 24.26400  1.000 44.45023  ? 379 ARG A N   1 
ATOM   2849 C CA  . ARG A 1 380 ? -25.74712 -29.55419 24.91158  1.000 47.56003  ? 379 ARG A CA  1 
ATOM   2850 C C   . ARG A 1 380 ? -26.65473 -30.62588 24.34194  1.000 44.13023  ? 379 ARG A C   1 
ATOM   2851 O O   . ARG A 1 380 ? -27.85598 -30.53384 24.57787  1.000 55.48341  ? 379 ARG A O   1 
ATOM   2852 C CB  . ARG A 1 380 ? -26.46897 -28.20625 24.79208  1.000 55.53576  ? 379 ARG A CB  1 
ATOM   2853 C CG  . ARG A 1 380 ? -25.62065 -26.97117 25.09269  1.000 58.65362  ? 379 ARG A CG  1 
ATOM   2854 C CD  . ARG A 1 380 ? -26.25126 -25.75691 24.44680  1.000 52.49415  ? 379 ARG A CD  1 
ATOM   2855 N NE  . ARG A 1 380 ? -26.45944 -24.62715 25.34703  1.000 56.65573  ? 379 ARG A NE  1 
ATOM   2856 C CZ  . ARG A 1 380 ? -25.60179 -23.62508 25.50069  1.000 55.94389  ? 379 ARG A CZ  1 
ATOM   2857 N NH1 . ARG A 1 380 ? -24.40514 -23.64675 24.93050  1.000 50.87892  ? 379 ARG A NH1 1 
ATOM   2858 N NH2 . ARG A 1 380 ? -25.96157 -22.56312 26.22522  1.000 53.13817  ? 379 ARG A NH2 1 
ATOM   2859 N N   . VAL A 1 381 ? -26.19508 -31.60967 23.57939  1.000 40.93930  ? 380 VAL A N   1 
ATOM   2860 C CA  . VAL A 1 381 ? -27.12874 -32.56491 22.98101  1.000 48.70739  ? 380 VAL A CA  1 
ATOM   2861 C C   . VAL A 1 381 ? -26.58824 -33.98495 23.10530  1.000 48.27834  ? 380 VAL A C   1 
ATOM   2862 O O   . VAL A 1 381 ? -25.37638 -34.21667 23.01953  1.000 50.46029  ? 380 VAL A O   1 
ATOM   2863 C CB  . VAL A 1 381 ? -27.46627 -32.23536 21.50260  1.000 47.23491  ? 380 VAL A CB  1 
ATOM   2864 C CG1 . VAL A 1 381 ? -28.12221 -30.86372 21.38461  1.000 46.66965  ? 380 VAL A CG1 1 
ATOM   2865 C CG2 . VAL A 1 381 ? -26.24194 -32.30921 20.62725  1.000 40.88945  ? 380 VAL A CG2 1 
ATOM   2866 N N   . ALA A 1 382 ? -27.50839 -34.93250 23.30475  1.000 41.77897  ? 381 ALA A N   1 
ATOM   2867 C CA  . ALA A 1 382 ? -27.20264 -36.34996 23.41425  1.000 44.47486  ? 381 ALA A CA  1 
ATOM   2868 C C   . ALA A 1 382 ? -26.53284 -36.88036 22.14242  1.000 49.33609  ? 381 ALA A C   1 
ATOM   2869 O O   . ALA A 1 382 ? -26.52787 -36.23818 21.09126  1.000 60.53280  ? 381 ALA A O   1 
ATOM   2870 C CB  . ALA A 1 382 ? -28.48093 -37.13484 23.68620  1.000 49.05897  ? 381 ALA A CB  1 
ATOM   2871 N N   . GLU A 1 383 ? -25.96221 -38.08265 22.24049  1.000 49.28754  ? 382 GLU A N   1 
ATOM   2872 C CA  . GLU A 1 383 ? -25.30160 -38.64344 21.06963  1.000 48.50677  ? 382 GLU A CA  1 
ATOM   2873 C C   . GLU A 1 383 ? -26.32238 -39.08816 20.04432  1.000 48.92870  ? 382 GLU A C   1 
ATOM   2874 O O   . GLU A 1 383 ? -26.10473 -38.93408 18.83860  1.000 59.89710  ? 382 GLU A O   1 
ATOM   2875 C CB  . GLU A 1 383 ? -24.38938 -39.80333 21.45455  1.000 55.83707  ? 382 GLU A CB  1 
ATOM   2876 C CG  . GLU A 1 383 ? -23.29214 -39.43666 22.44643  1.000 61.77291  ? 382 GLU A CG  1 
ATOM   2877 C CD  . GLU A 1 383 ? -23.00329 -40.55696 23.43911  1.000 73.50340  ? 382 GLU A CD  1 
ATOM   2878 O OE1 . GLU A 1 383 ? -23.24824 -41.74083 23.10329  1.000 74.58474  ? 382 GLU A OE1 1 
ATOM   2879 O OE2 . GLU A 1 383 ? -22.53833 -40.25638 24.55944  1.000 77.50989  ? 382 GLU A OE2 1 
ATOM   2880 N N   . HIS A 1 384 ? -27.45670 -39.60511 20.50403  1.000 48.43342  ? 383 HIS A N   1 
ATOM   2881 C CA  . HIS A 1 384 ? -28.52402 -40.02260 19.60535  1.000 44.26453  ? 383 HIS A CA  1 
ATOM   2882 C C   . HIS A 1 384 ? -29.36081 -38.85992 19.08649  1.000 45.68720  ? 383 HIS A C   1 
ATOM   2883 O O   . HIS A 1 384 ? -30.18147 -39.06690 18.19186  1.000 58.83545  ? 383 HIS A O   1 
ATOM   2884 C CB  . HIS A 1 384 ? -29.44443 -41.02277 20.30806  1.000 43.38364  ? 383 HIS A CB  1 
ATOM   2885 C CG  . HIS A 1 384 ? -30.15815 -40.45197 21.49571  1.000 47.31086  ? 383 HIS A CG  1 
ATOM   2886 N ND1 . HIS A 1 384 ? -29.56125 -40.32156 22.73370  1.000 46.22095  ? 383 HIS A ND1 1 
ATOM   2887 C CD2 . HIS A 1 384 ? -31.41072 -39.95278 21.62722  1.000 44.56517  ? 383 HIS A CD2 1 
ATOM   2888 C CE1 . HIS A 1 384 ? -30.42111 -39.78130 23.57931  1.000 45.69565  ? 383 HIS A CE1 1 
ATOM   2889 N NE2 . HIS A 1 384 ? -31.54697 -39.53834 22.93136  1.000 47.96298  ? 383 HIS A NE2 1 
ATOM   2890 N N   . GLU A 1 385 ? -29.20203 -37.65518 19.62145  1.000 46.62108  ? 384 GLU A N   1 
ATOM   2891 C CA  . GLU A 1 385 ? -29.95880 -36.53214 19.09162  1.000 43.17009  ? 384 GLU A CA  1 
ATOM   2892 C C   . GLU A 1 385 ? -29.32030 -36.01734 17.79987  1.000 38.35655  ? 384 GLU A C   1 
ATOM   2893 O O   . GLU A 1 385 ? -28.21250 -36.40110 17.41379  1.000 41.69947  ? 384 GLU A O   1 
ATOM   2894 C CB  . GLU A 1 385 ? -30.07621 -35.42242 20.13816  1.000 37.33358  ? 384 GLU A CB  1 
ATOM   2895 C CG  . GLU A 1 385 ? -31.10402 -35.74988 21.20537  1.000 39.10685  ? 384 GLU A CG  1 
ATOM   2896 C CD  . GLU A 1 385 ? -31.13918 -34.74038 22.33446  1.000 47.37643  ? 384 GLU A CD  1 
ATOM   2897 O OE1 . GLU A 1 385 ? -30.12680 -34.04179 22.55574  1.000 49.40028  ? 384 GLU A OE1 1 
ATOM   2898 O OE2 . GLU A 1 385 ? -32.18449 -34.64867 23.01171  1.000 47.56323  ? 384 GLU A OE2 1 
ATOM   2899 N N   . GLN A 1 386 ? -30.03886 -35.12110 17.13933  1.000 33.71120  ? 385 GLN A N   1 
ATOM   2900 C CA  . GLN A 1 386 ? -29.67551 -34.60102 15.83134  1.000 31.54439  ? 385 GLN A CA  1 
ATOM   2901 C C   . GLN A 1 386 ? -30.04575 -33.12451 15.76920  1.000 32.97764  ? 385 GLN A C   1 
ATOM   2902 O O   . GLN A 1 386 ? -31.13709 -32.74672 16.20035  1.000 35.72235  ? 385 GLN A O   1 
ATOM   2903 C CB  . GLN A 1 386 ? -30.40739 -35.39586 14.76031  1.000 30.02789  ? 385 GLN A CB  1 
ATOM   2904 C CG  . GLN A 1 386 ? -30.14802 -35.00714 13.36048  1.000 36.21611  ? 385 GLN A CG  1 
ATOM   2905 C CD  . GLN A 1 386 ? -31.23918 -35.54617 12.45218  1.000 52.88658  ? 385 GLN A CD  1 
ATOM   2906 O OE1 . GLN A 1 386 ? -32.29805 -36.00124 12.93526  1.000 49.62362  ? 385 GLN A OE1 1 
ATOM   2907 N NE2 . GLN A 1 386 ? -31.00140 -35.49407 11.13057  1.000 48.51516  ? 385 GLN A NE2 1 
ATOM   2908 N N   . LEU A 1 387 ? -29.14078 -32.28991 15.26234  1.000 30.57753  ? 386 LEU A N   1 
ATOM   2909 C CA  . LEU A 1 387 ? -29.38968 -30.86494 15.08981  1.000 30.16140  ? 386 LEU A CA  1 
ATOM   2910 C C   . LEU A 1 387 ? -29.74727 -30.54463 13.63507  1.000 35.68441  ? 386 LEU A C   1 
ATOM   2911 O O   . LEU A 1 387 ? -29.26536 -31.19345 12.69976  1.000 35.78067  ? 386 LEU A O   1 
ATOM   2912 C CB  . LEU A 1 387 ? -28.16744 -30.05870 15.51712  1.000 27.43889  ? 386 LEU A CB  1 
ATOM   2913 C CG  . LEU A 1 387 ? -27.82397 -30.24696 16.99058  1.000 31.18260  ? 386 LEU A CG  1 
ATOM   2914 C CD1 . LEU A 1 387 ? -26.57004 -29.50378 17.35920  1.000 32.31375  ? 386 LEU A CD1 1 
ATOM   2915 C CD2 . LEU A 1 387 ? -28.98199 -29.77340 17.85284  1.000 40.76679  ? 386 LEU A CD2 1 
ATOM   2916 N N   . THR A 1 388 ? -30.61554 -29.54682 13.44890  1.000 31.03949  ? 387 THR A N   1 
ATOM   2917 C CA  . THR A 1 388 ? -30.99218 -29.12582 12.10458  1.000 31.02626  ? 387 THR A CA  1 
ATOM   2918 C C   . THR A 1 388 ? -31.45610 -27.68142 12.12614  1.000 33.77161  ? 387 THR A C   1 
ATOM   2919 O O   . THR A 1 388 ? -32.15893 -27.25909 13.05220  1.000 38.57558  ? 387 THR A O   1 
ATOM   2920 C CB  . THR A 1 388 ? -32.10119 -29.99501 11.49244  1.000 33.77748  ? 387 THR A CB  1 
ATOM   2921 O OG1 . THR A 1 388 ? -32.38301 -29.52944 10.17032  1.000 36.08561  ? 387 THR A OG1 1 
ATOM   2922 C CG2 . THR A 1 388 ? -33.38259 -29.90735 12.28430  1.000 33.86265  ? 387 THR A CG2 1 
ATOM   2923 N N   . THR A 1 389 ? -31.04531 -26.92832 11.10816  1.000 31.22017  ? 388 THR A N   1 
ATOM   2924 C CA  . THR A 1 389 ? -31.60826 -25.60438 10.91693  1.000 31.78983  ? 388 THR A CA  1 
ATOM   2925 C C   . THR A 1 389 ? -33.11057 -25.73770 10.77104  1.000 32.10047  ? 388 THR A C   1 
ATOM   2926 O O   . THR A 1 389 ? -33.60359 -26.68797 10.16289  1.000 35.18511  ? 388 THR A O   1 
ATOM   2927 C CB  . THR A 1 389 ? -31.00948 -24.93212 9.68595   1.000 35.75019  ? 388 THR A CB  1 
ATOM   2928 O OG1 . THR A 1 389 ? -31.65720 -23.67068 9.46643   1.000 42.56701  ? 388 THR A OG1 1 
ATOM   2929 C CG2 . THR A 1 389 ? -31.17964 -25.81055 8.46129   1.000 33.81053  ? 388 THR A CG2 1 
ATOM   2930 N N   . MET A 1 390 ? -33.85337 -24.81203 11.37327  1.000 35.13255  ? 389 MET A N   1 
ATOM   2931 C CA  . MET A 1 390 ? -35.30197 -24.90108 11.23366  1.000 35.84568  ? 389 MET A CA  1 
ATOM   2932 C C   . MET A 1 390 ? -35.70397 -24.73482 9.77788   1.000 34.06851  ? 389 MET A C   1 
ATOM   2933 O O   . MET A 1 390 ? -36.66739 -25.35534 9.32408   1.000 35.56293  ? 389 MET A O   1 
ATOM   2934 C CB  . MET A 1 390 ? -36.01906 -23.87954 12.12741  1.000 31.03730  ? 389 MET A CB  1 
ATOM   2935 C CG  . MET A 1 390 ? -37.41060 -24.35888 12.48987  1.000 34.47062  ? 389 MET A CG  1 
ATOM   2936 S SD  . MET A 1 390 ? -38.53441 -23.23289 13.33349  1.000 36.26773  ? 389 MET A SD  1 
ATOM   2937 C CE  . MET A 1 390 ? -38.03916 -21.65550 12.66642  1.000 36.89762  ? 389 MET A CE  1 
ATOM   2938 N N   . ALA A 1 391 ? -34.93567 -23.95631 9.01854   1.000 33.82676  ? 390 ALA A N   1 
ATOM   2939 C CA  . ALA A 1 391 ? -35.19748 -23.78451 7.60497   1.000 29.03061  ? 390 ALA A CA  1 
ATOM   2940 C C   . ALA A 1 391 ? -35.32795 -25.12034 6.88652   1.000 31.07371  ? 390 ALA A C   1 
ATOM   2941 O O   . ALA A 1 391 ? -35.87324 -25.17824 5.78206   1.000 33.52590  ? 390 ALA A O   1 
ATOM   2942 C CB  . ALA A 1 391 ? -34.07890 -22.93165 7.00758   1.000 34.73310  ? 390 ALA A CB  1 
ATOM   2943 N N   . ALA A 1 392 ? -34.87953 -26.20835 7.49972   1.000 36.46463  ? 391 ALA A N   1 
ATOM   2944 C CA  . ALA A 1 392 ? -35.00180 -27.50774 6.85359   1.000 37.39975  ? 391 ALA A CA  1 
ATOM   2945 C C   . ALA A 1 392 ? -36.44986 -27.98159 6.71744   1.000 32.96339  ? 391 ALA A C   1 
ATOM   2946 O O   . ALA A 1 392 ? -36.70809 -28.86912 5.90388   1.000 34.04212  ? 391 ALA A O   1 
ATOM   2947 C CB  . ALA A 1 392 ? -34.17560 -28.54557 7.61824   1.000 33.35027  ? 391 ALA A CB  1 
ATOM   2948 N N   . LEU A 1 393 ? -37.40150 -27.43783 7.48861   1.000 30.25730  ? 392 LEU A N   1 
ATOM   2949 C CA  . LEU A 1 393 ? -38.78413 -27.89304 7.33386   1.000 30.73392  ? 392 LEU A CA  1 
ATOM   2950 C C   . LEU A 1 393 ? -39.37516 -27.42307 6.01127   1.000 34.07535  ? 392 LEU A C   1 
ATOM   2951 O O   . LEU A 1 393 ? -40.27522 -28.07088 5.46208   1.000 36.72900  ? 392 LEU A O   1 
ATOM   2952 C CB  . LEU A 1 393 ? -39.66304 -27.41549 8.49219   1.000 33.04397  ? 392 LEU A CB  1 
ATOM   2953 C CG  . LEU A 1 393 ? -39.31164 -27.58723 9.97335   1.000 28.05761  ? 392 LEU A CG  1 
ATOM   2954 C CD1 . LEU A 1 393 ? -40.54098 -27.28600 10.81615  1.000 28.49668  ? 392 LEU A CD1 1 
ATOM   2955 C CD2 . LEU A 1 393 ? -38.76093 -28.96830 10.26826  1.000 26.96140  ? 392 LEU A CD2 1 
ATOM   2956 N N   . LEU A 1 394 ? -38.86722 -26.31986 5.47685   1.000 34.77380  ? 393 LEU A N   1 
ATOM   2957 C CA  . LEU A 1 394 ? -39.26313 -25.81981 4.17215   1.000 29.47716  ? 393 LEU A CA  1 
ATOM   2958 C C   . LEU A 1 394 ? -38.38565 -26.34524 3.02981   1.000 32.23264  ? 393 LEU A C   1 
ATOM   2959 O O   . LEU A 1 394 ? -38.55554 -25.90932 1.88478   1.000 36.13531  ? 393 LEU A O   1 
ATOM   2960 C CB  . LEU A 1 394 ? -39.26132 -24.29195 4.20370   1.000 25.48039  ? 393 LEU A CB  1 
ATOM   2961 C CG  . LEU A 1 394 ? -40.22540 -23.76745 5.26863   1.000 31.99696  ? 393 LEU A CG  1 
ATOM   2962 C CD1 . LEU A 1 394 ? -40.30745 -22.25264 5.28447   1.000 30.42505  ? 393 LEU A CD1 1 
ATOM   2963 C CD2 . LEU A 1 394 ? -41.59848 -24.37463 5.06496   1.000 33.34383  ? 393 LEU A CD2 1 
ATOM   2964 N N   . HIS A 1 395 ? -37.47979 -27.28492 3.29519   1.000 29.21494  ? 394 HIS A N   1 
ATOM   2965 C CA  . HIS A 1 395 ? -36.63960 -27.82097 2.23492   1.000 31.20803  ? 394 HIS A CA  1 
ATOM   2966 C C   . HIS A 1 395 ? -37.38960 -28.87471 1.44695   1.000 35.63467  ? 394 HIS A C   1 
ATOM   2967 O O   . HIS A 1 395 ? -38.14864 -29.66476 2.01283   1.000 39.95480  ? 394 HIS A O   1 
ATOM   2968 C CB  . HIS A 1 395 ? -35.35619 -28.43066 2.78685   1.000 34.14823  ? 394 HIS A CB  1 
ATOM   2969 C CG  . HIS A 1 395 ? -34.37196 -28.84210 1.72965   1.000 36.13685  ? 394 HIS A CG  1 
ATOM   2970 N ND1 . HIS A 1 395 ? -33.70866 -27.93194 0.93383   1.000 34.98250  ? 394 HIS A ND1 1 
ATOM   2971 C CD2 . HIS A 1 395 ? -33.90992 -30.06382 1.36321   1.000 40.93647  ? 394 HIS A CD2 1 
ATOM   2972 C CE1 . HIS A 1 395 ? -32.89510 -28.57619 0.11200   1.000 36.52833  ? 394 HIS A CE1 1 
ATOM   2973 N NE2 . HIS A 1 395 ? -33.00340 -29.87221 0.34308   1.000 33.88827  ? 394 HIS A NE2 1 
ATOM   2974 N N   . ILE A 1 396 ? -37.16932 -28.86804 0.12964   1.000 37.90155  ? 395 ILE A N   1 
ATOM   2975 C CA  . ILE A 1 396 ? -37.71237 -29.84248 -0.81308  1.000 37.27687  ? 395 ILE A CA  1 
ATOM   2976 C C   . ILE A 1 396 ? -36.57099 -30.29373 -1.70891  1.000 33.13872  ? 395 ILE A C   1 
ATOM   2977 O O   . ILE A 1 396 ? -35.83841 -29.45886 -2.24365  1.000 35.44792  ? 395 ILE A O   1 
ATOM   2978 C CB  . ILE A 1 396 ? -38.84355 -29.23800 -1.66633  1.000 35.86089  ? 395 ILE A CB  1 
ATOM   2979 C CG1 . ILE A 1 396 ? -39.92731 -28.63830 -0.76936  1.000 29.76197  ? 395 ILE A CG1 1 
ATOM   2980 C CG2 . ILE A 1 396 ? -39.36956 -30.25367 -2.66617  1.000 28.50742  ? 395 ILE A CG2 1 
ATOM   2981 C CD1 . ILE A 1 396 ? -41.03105 -28.02699 -1.53632  1.000 26.28261  ? 395 ILE A CD1 1 
ATOM   2982 N N   . ASP A 1 397 ? -36.41649 -31.59666 -1.88340  1.000 37.19514  ? 396 ASP A N   1 
ATOM   2983 C CA  . ASP A 1 397 ? -35.28620 -32.03280 -2.69079  1.000 41.65883  ? 396 ASP A CA  1 
ATOM   2984 C C   . ASP A 1 397 ? -35.60832 -31.93367 -4.19001  1.000 40.35547  ? 396 ASP A C   1 
ATOM   2985 O O   . ASP A 1 397 ? -36.75584 -31.75221 -4.60583  1.000 41.37374  ? 396 ASP A O   1 
ATOM   2986 C CB  . ASP A 1 397 ? -34.83212 -33.44705 -2.27858  1.000 43.69898  ? 396 ASP A CB  1 
ATOM   2987 C CG  . ASP A 1 397 ? -35.70712 -34.58734 -2.85141  1.000 44.82897  ? 396 ASP A CG  1 
ATOM   2988 O OD1 . ASP A 1 397 ? -36.81719 -34.34022 -3.37657  1.000 43.89702  ? 396 ASP A OD1 1 
ATOM   2989 O OD2 . ASP A 1 397 ? -35.26745 -35.76315 -2.75296  1.000 43.53988  ? 396 ASP A OD2 1 
ATOM   2990 N N   . HIS A 1 398 ? -34.55476 -32.04543 -5.00061  1.000 38.71264  ? 397 HIS A N   1 
ATOM   2991 C CA  . HIS A 1 398 ? -34.66360 -31.92360 -6.45089  1.000 43.21224  ? 397 HIS A CA  1 
ATOM   2992 C C   . HIS A 1 398 ? -35.68215 -32.89167 -7.06205  1.000 44.51482  ? 397 HIS A C   1 
ATOM   2993 O O   . HIS A 1 398 ? -36.21456 -32.62785 -8.14726  1.000 44.98561  ? 397 HIS A O   1 
ATOM   2994 C CB  . HIS A 1 398 ? -33.28321 -32.13989 -7.07055  1.000 43.03587  ? 397 HIS A CB  1 
ATOM   2995 C CG  . HIS A 1 398 ? -32.62857 -33.41569 -6.63632  1.000 49.86875  ? 397 HIS A CG  1 
ATOM   2996 N ND1 . HIS A 1 398 ? -32.30557 -33.67985 -5.32126  1.000 47.10554  ? 397 HIS A ND1 1 
ATOM   2997 C CD2 . HIS A 1 398 ? -32.26662 -34.51574 -7.33765  1.000 52.99589  ? 397 HIS A CD2 1 
ATOM   2998 C CE1 . HIS A 1 398 ? -31.75876 -34.87817 -5.23285  1.000 44.78596  ? 397 HIS A CE1 1 
ATOM   2999 N NE2 . HIS A 1 398 ? -31.72811 -35.40932 -6.44157  1.000 55.02868  ? 397 HIS A NE2 1 
ATOM   3000 N N   . ASN A 1 399 ? -35.96170 -34.01357 -6.40362  1.000 40.55921  ? 398 ASN A N   1 
ATOM   3001 C CA  . ASN A 1 399 ? -37.05163 -34.86865 -6.85533  1.000 38.59940  ? 398 ASN A CA  1 
ATOM   3002 C C   . ASN A 1 399 ? -38.40727 -34.40720 -6.35579  1.000 41.22537  ? 398 ASN A C   1 
ATOM   3003 O O   . ASN A 1 399 ? -39.39729 -35.10235 -6.59115  1.000 43.19394  ? 398 ASN A O   1 
ATOM   3004 C CB  . ASN A 1 399 ? -36.83513 -36.30867 -6.40652  1.000 40.28475  ? 398 ASN A CB  1 
ATOM   3005 C CG  . ASN A 1 399 ? -35.62300 -36.94158 -7.05371  1.000 56.01830  ? 398 ASN A CG  1 
ATOM   3006 O OD1 . ASN A 1 399 ? -35.45673 -36.90757 -8.28278  1.000 59.11393  ? 398 ASN A OD1 1 
ATOM   3007 N ND2 . ASN A 1 399 ? -34.75682 -37.52811 -6.22574  1.000 61.82997  ? 398 ASN A ND2 1 
ATOM   3008 N N   . GLY A 1 400 ? -38.48018 -33.27640 -5.65790  1.000 39.93000  ? 399 GLY A N   1 
ATOM   3009 C CA  . GLY A 1 400 ? -39.75409 -32.79662 -5.16034  1.000 38.43919  ? 399 GLY A CA  1 
ATOM   3010 C C   . GLY A 1 400 ? -40.23008 -33.43746 -3.88066  1.000 37.32803  ? 399 GLY A C   1 
ATOM   3011 O O   . GLY A 1 400 ? -41.43011 -33.39234 -3.58971  1.000 34.95792  ? 399 GLY A O   1 
ATOM   3012 N N   . ILE A 1 401 ? -39.32706 -34.02145 -3.10250  1.000 39.03079  ? 400 ILE A N   1 
ATOM   3013 C CA  . ILE A 1 401 ? -39.65955 -34.66923 -1.83488  1.000 40.59960  ? 400 ILE A CA  1 
ATOM   3014 C C   . ILE A 1 401 ? -39.37760 -33.68840 -0.70457  1.000 38.96650  ? 400 ILE A C   1 
ATOM   3015 O O   . ILE A 1 401 ? -38.21507 -33.28650 -0.52420  1.000 35.13549  ? 400 ILE A O   1 
ATOM   3016 C CB  . ILE A 1 401 ? -38.86322 -35.96217 -1.63027  1.000 39.34762  ? 400 ILE A CB  1 
ATOM   3017 C CG1 . ILE A 1 401 ? -38.95482 -36.81992 -2.88565  1.000 38.72683  ? 400 ILE A CG1 1 
ATOM   3018 C CG2 . ILE A 1 401 ? -39.34439 -36.66993 -0.39414  1.000 35.85039  ? 400 ILE A CG2 1 
ATOM   3019 C CD1 . ILE A 1 401 ? -40.27546 -37.51314 -3.01445  1.000 41.10824  ? 400 ILE A CD1 1 
ATOM   3020 N N   . PRO A 1 402 ? -40.38289 -33.30150 0.08116   1.000 36.93452  ? 401 PRO A N   1 
ATOM   3021 C CA  . PRO A 1 402 ? -40.16344 -32.34177 1.16887   1.000 35.69604  ? 401 PRO A CA  1 
ATOM   3022 C C   . PRO A 1 402 ? -39.43692 -33.01484 2.32160   1.000 36.94431  ? 401 PRO A C   1 
ATOM   3023 O O   . PRO A 1 402 ? -39.89847 -34.02637 2.85667   1.000 40.36003  ? 401 PRO A O   1 
ATOM   3024 C CB  . PRO A 1 402 ? -41.58478 -31.91968 1.55564   1.000 35.91308  ? 401 PRO A CB  1 
ATOM   3025 C CG  . PRO A 1 402 ? -42.41759 -33.06774 1.19632   1.000 29.92510  ? 401 PRO A CG  1 
ATOM   3026 C CD  . PRO A 1 402 ? -41.77761 -33.75258 0.01838   1.000 30.31775  ? 401 PRO A CD  1 
ATOM   3027 N N   . LEU A 1 403 ? -38.28055 -32.45957 2.68549   1.000 32.19975  ? 402 LEU A N   1 
ATOM   3028 C CA  . LEU A 1 403 ? -37.50308 -33.04190 3.76489   1.000 33.73969  ? 402 LEU A CA  1 
ATOM   3029 C C   . LEU A 1 403 ? -38.33717 -33.17245 5.02920   1.000 37.41098  ? 402 LEU A C   1 
ATOM   3030 O O   . LEU A 1 403 ? -38.15854 -34.12622 5.79560   1.000 35.82228  ? 402 LEU A O   1 
ATOM   3031 C CB  . LEU A 1 403 ? -36.25842 -32.19301 4.01885   1.000 33.79146  ? 402 LEU A CB  1 
ATOM   3032 C CG  . LEU A 1 403 ? -35.37038 -32.53282 5.22179   1.000 35.05207  ? 402 LEU A CG  1 
ATOM   3033 C CD1 . LEU A 1 403 ? -34.96790 -34.00355 5.23445   1.000 33.91028  ? 402 LEU A CD1 1 
ATOM   3034 C CD2 . LEU A 1 403 ? -34.14530 -31.63479 5.22461   1.000 34.53931  ? 402 LEU A CD2 1 
ATOM   3035 N N   . ALA A 1 404 ? -39.26652 -32.23909 5.25128   1.000 35.18997  ? 403 ALA A N   1 
ATOM   3036 C CA  . ALA A 1 404 ? -40.10732 -32.31554 6.43748   1.000 33.82589  ? 403 ALA A CA  1 
ATOM   3037 C C   . ALA A 1 404 ? -40.77140 -33.68267 6.55962   1.000 39.85528  ? 403 ALA A C   1 
ATOM   3038 O O   . ALA A 1 404 ? -40.79200 -34.28380 7.64325   1.000 41.37471  ? 403 ALA A O   1 
ATOM   3039 C CB  . ALA A 1 404 ? -41.15934 -31.20991 6.40349   1.000 32.24078  ? 403 ALA A CB  1 
ATOM   3040 N N   . GLY A 1 405 ? -41.29584 -34.20681 5.45305   1.000 35.33320  ? 404 GLY A N   1 
ATOM   3041 C CA  . GLY A 1 405 ? -41.96474 -35.49301 5.51134   1.000 34.26512  ? 404 GLY A CA  1 
ATOM   3042 C C   . GLY A 1 405 ? -41.03485 -36.66537 5.77104   1.000 39.18414  ? 404 GLY A C   1 
ATOM   3043 O O   . GLY A 1 405 ? -41.46868 -37.69396 6.28949   1.000 39.74683  ? 404 GLY A O   1 
ATOM   3044 N N   . GLU A 1 406 ? -39.75887 -36.55082 5.39693   1.000 36.86733  ? 405 GLU A N   1 
ATOM   3045 C CA  . GLU A 1 406 ? -38.81734 -37.59587 5.78007   1.000 37.22759  ? 405 GLU A CA  1 
ATOM   3046 C C   . GLU A 1 406 ? -38.54760 -37.58716 7.28954   1.000 40.37721  ? 405 GLU A C   1 
ATOM   3047 O O   . GLU A 1 406 ? -38.31140 -38.64857 7.88448   1.000 37.12161  ? 405 GLU A O   1 
ATOM   3048 C CB  . GLU A 1 406 ? -37.52820 -37.44543 4.97850   1.000 39.34910  ? 405 GLU A CB  1 
ATOM   3049 C CG  . GLU A 1 406 ? -37.70045 -37.75126 3.49051   1.000 43.83002  ? 405 GLU A CG  1 
ATOM   3050 C CD  . GLU A 1 406 ? -38.52729 -39.02520 3.23265   1.000 56.01693  ? 405 GLU A CD  1 
ATOM   3051 O OE1 . GLU A 1 406 ? -38.14861 -40.10544 3.76077   1.000 55.40993  ? 405 GLU A OE1 1 
ATOM   3052 O OE2 . GLU A 1 406 ? -39.55201 -38.94776 2.49849   1.000 51.46625  ? 405 GLU A OE2 1 
ATOM   3053 N N   . PHE A 1 407 ? -38.61263 -36.41444 7.93393   1.000 38.42308  ? 406 PHE A N   1 
ATOM   3054 C CA  . PHE A 1 407 ? -38.57973 -36.37354 9.39512   1.000 37.69186  ? 406 PHE A CA  1 
ATOM   3055 C C   . PHE A 1 407 ? -39.82633 -37.02366 10.00129  1.000 40.17304  ? 406 PHE A C   1 
ATOM   3056 O O   . PHE A 1 407 ? -39.73621 -37.75734 10.99427  1.000 37.80857  ? 406 PHE A O   1 
ATOM   3057 C CB  . PHE A 1 407 ? -38.42888 -34.93088 9.87947   1.000 33.20851  ? 406 PHE A CB  1 
ATOM   3058 C CG  . PHE A 1 407 ? -37.05130 -34.37037 9.69192   1.000 37.28810  ? 406 PHE A CG  1 
ATOM   3059 C CD1 . PHE A 1 407 ? -35.92632 -35.14700 9.95571   1.000 43.40400  ? 406 PHE A CD1 1 
ATOM   3060 C CD2 . PHE A 1 407 ? -36.87082 -33.06552 9.24160   1.000 38.14980  ? 406 PHE A CD2 1 
ATOM   3061 C CE1 . PHE A 1 407 ? -34.63423 -34.62671 9.77022   1.000 44.18812  ? 406 PHE A CE1 1 
ATOM   3062 C CE2 . PHE A 1 407 ? -35.58862 -32.53726 9.05303   1.000 33.65906  ? 406 PHE A CE2 1 
ATOM   3063 C CZ  . PHE A 1 407 ? -34.47123 -33.30861 9.32161   1.000 33.75398  ? 406 PHE A CZ  1 
ATOM   3064 N N   . ILE A 1 408 ? -40.99579 -36.78077 9.41011   1.000 39.33708  ? 407 ILE A N   1 
ATOM   3065 C CA  . ILE A 1 408 ? -42.23724 -37.33354 9.94619   1.000 34.80354  ? 407 ILE A CA  1 
ATOM   3066 C C   . ILE A 1 408 ? -42.24562 -38.85623 9.85828   1.000 39.23909  ? 407 ILE A C   1 
ATOM   3067 O O   . ILE A 1 408 ? -42.61282 -39.53788 10.82353  1.000 43.19448  ? 407 ILE A O   1 
ATOM   3068 C CB  . ILE A 1 408 ? -43.44445 -36.72431 9.21752   1.000 39.32067  ? 407 ILE A CB  1 
ATOM   3069 C CG1 . ILE A 1 408 ? -43.45660 -35.19664 9.42212   1.000 41.16162  ? 407 ILE A CG1 1 
ATOM   3070 C CG2 . ILE A 1 408 ? -44.73499 -37.41577 9.66885   1.000 39.04962  ? 407 ILE A CG2 1 
ATOM   3071 C CD1 . ILE A 1 408 ? -44.40410 -34.42118 8.50199   1.000 31.59148  ? 407 ILE A CD1 1 
ATOM   3072 N N   . GLN A 1 409 ? -41.86785 -39.41857 8.69884   1.000 39.58590  ? 408 GLN A N   1 
ATOM   3073 C CA  . GLN A 1 409 ? -41.87134 -40.87419 8.56661   1.000 36.23983  ? 408 GLN A CA  1 
ATOM   3074 C C   . GLN A 1 409 ? -40.88156 -41.50774 9.52996   1.000 39.88873  ? 408 GLN A C   1 
ATOM   3075 O O   . GLN A 1 409 ? -41.24258 -42.41075 10.30007  1.000 42.19698  ? 408 GLN A O   1 
ATOM   3076 C CB  . GLN A 1 409 ? -41.58789 -41.31598 7.12735   1.000 41.53728  ? 408 GLN A CB  1 
ATOM   3077 C CG  . GLN A 1 409 ? -42.30991 -40.54263 6.02746   1.000 53.87344  ? 408 GLN A CG  1 
ATOM   3078 C CD  . GLN A 1 409 ? -41.92411 -41.00938 4.60404   1.000 72.85360  ? 408 GLN A CD  1 
ATOM   3079 O OE1 . GLN A 1 409 ? -42.56797 -40.63324 3.60735   1.000 66.34379  ? 408 GLN A OE1 1 
ATOM   3080 N NE2 . GLN A 1 409 ? -40.86348 -41.82539 4.51064   1.000 76.85091  ? 408 GLN A NE2 1 
ATOM   3081 N N   . LYS A 1 410 ? -39.63328 -41.02598 9.53003   1.000 35.56595  ? 409 LYS A N   1 
ATOM   3082 C CA  . LYS A 1 410 ? -38.64720 -41.58960 10.44422  1.000 35.98290  ? 409 LYS A CA  1 
ATOM   3083 C C   . LYS A 1 410 ? -39.09764 -41.54508 11.89370  1.000 39.80227  ? 409 LYS A C   1 
ATOM   3084 O O   . LYS A 1 410 ? -38.59675 -42.32794 12.71154  1.000 40.76012  ? 409 LYS A O   1 
ATOM   3085 C CB  . LYS A 1 410 ? -37.31412 -40.85322 10.36430  1.000 35.84134  ? 409 LYS A CB  1 
ATOM   3086 C CG  . LYS A 1 410 ? -36.13503 -41.75402 10.64505  1.000 38.66208  ? 409 LYS A CG  1 
ATOM   3087 C CD  . LYS A 1 410 ? -35.01808 -41.00945 11.37298  1.000 45.43467  ? 409 LYS A CD  1 
ATOM   3088 C CE  . LYS A 1 410 ? -34.88180 -39.54294 10.94312  1.000 46.02579  ? 409 LYS A CE  1 
ATOM   3089 N NZ  . LYS A 1 410 ? -33.73056 -38.82543 11.61393  1.000 48.16930  ? 409 LYS A NZ  1 
ATOM   3090 N N   . SER A 1 411 ? -40.01199 -40.63289 12.22904  1.000 36.77609  ? 410 SER A N   1 
ATOM   3091 C CA  . SER A 1 411 ? -40.23143 -40.25749 13.61351  1.000 38.76126  ? 410 SER A CA  1 
ATOM   3092 C C   . SER A 1 411 ? -41.12252 -41.23156 14.36741  1.000 41.04075  ? 410 SER A C   1 
ATOM   3093 O O   . SER A 1 411 ? -41.14842 -41.19252 15.59950  1.000 39.72284  ? 410 SER A O   1 
ATOM   3094 C CB  . SER A 1 411 ? -40.84088 -38.85708 13.67931  1.000 35.47124  ? 410 SER A CB  1 
ATOM   3095 O OG  . SER A 1 411 ? -42.24649 -38.92827 13.57578  1.000 34.50935  ? 410 SER A OG  1 
ATOM   3096 N N   . GLY A 1 412 ? -41.86160 -42.08826 13.67926  1.000 37.88172  ? 411 GLY A N   1 
ATOM   3097 C CA  . GLY A 1 412 ? -42.82435 -42.84921 14.43351  1.000 38.61432  ? 411 GLY A CA  1 
ATOM   3098 C C   . GLY A 1 412 ? -43.99252 -42.03745 14.95663  1.000 48.00371  ? 411 GLY A C   1 
ATOM   3099 O O   . GLY A 1 412 ? -44.79647 -42.55809 15.75311  1.000 51.17644  ? 411 GLY A O   1 
ATOM   3100 N N   . LEU A 1 413 ? -44.12478 -40.77967 14.54035  1.000 34.69759  ? 412 LEU A N   1 
ATOM   3101 C CA  . LEU A 1 413 ? -45.28840 -39.98699 14.89683  1.000 34.43603  ? 412 LEU A CA  1 
ATOM   3102 C C   . LEU A 1 413 ? -46.11882 -39.69926 13.64706  1.000 33.31618  ? 412 LEU A C   1 
ATOM   3103 O O   . LEU A 1 413 ? -45.59723 -39.62633 12.53289  1.000 40.10012  ? 412 LEU A O   1 
ATOM   3104 C CB  . LEU A 1 413 ? -44.87163 -38.68270 15.60023  1.000 35.60081  ? 412 LEU A CB  1 
ATOM   3105 C CG  . LEU A 1 413 ? -43.86743 -38.84601 16.75300  1.000 33.58529  ? 412 LEU A CG  1 
ATOM   3106 C CD1 . LEU A 1 413 ? -43.44810 -37.52925 17.39838  1.000 30.22384  ? 412 LEU A CD1 1 
ATOM   3107 C CD2 . LEU A 1 413 ? -44.45148 -39.74072 17.77762  1.000 29.10271  ? 412 LEU A CD2 1 
ATOM   3108 N N   . ALA A 1 414 ? -47.42928 -39.58778 13.83176  1.000 33.26520  ? 413 ALA A N   1 
ATOM   3109 C CA  . ALA A 1 414 ? -48.28437 -39.01696 12.80518  1.000 27.77515  ? 413 ALA A CA  1 
ATOM   3110 C C   . ALA A 1 414 ? -47.92929 -37.54732 12.56992  1.000 38.12565  ? 413 ALA A C   1 
ATOM   3111 O O   . ALA A 1 414 ? -47.40458 -36.85779 13.45731  1.000 36.60865  ? 413 ALA A O   1 
ATOM   3112 C CB  . ALA A 1 414 ? -49.74814 -39.12507 13.21130  1.000 20.59925  ? 413 ALA A CB  1 
ATOM   3113 N N   . ALA A 1 415 ? -48.23484 -37.06127 11.35749  1.000 39.63730  ? 414 ALA A N   1 
ATOM   3114 C CA  . ALA A 1 415 ? -47.94144 -35.66866 11.01857  1.000 33.45048  ? 414 ALA A CA  1 
ATOM   3115 C C   . ALA A 1 415 ? -48.53305 -34.70375 12.04775  1.000 33.21874  ? 414 ALA A C   1 
ATOM   3116 O O   . ALA A 1 415 ? -47.81665 -33.88364 12.62755  1.000 33.67305  ? 414 ALA A O   1 
ATOM   3117 C CB  . ALA A 1 415 ? -48.45343 -35.35155 9.61515   1.000 32.32873  ? 414 ALA A CB  1 
ATOM   3118 N N   . GLN A 1 416 ? -49.83854 -34.80332 12.30462  1.000 35.49465  ? 415 GLN A N   1 
ATOM   3119 C CA  . GLN A 1 416 ? -50.47745 -33.94149 13.29713  1.000 32.18235  ? 415 GLN A CA  1 
ATOM   3120 C C   . GLN A 1 416 ? -49.69486 -33.92290 14.61576  1.000 36.93002  ? 415 GLN A C   1 
ATOM   3121 O O   . GLN A 1 416 ? -49.43297 -32.86044 15.19054  1.000 37.68991  ? 415 GLN A O   1 
ATOM   3122 C CB  . GLN A 1 416 ? -51.91243 -34.42152 13.52075  1.000 33.32344  ? 415 GLN A CB  1 
ATOM   3123 C CG  . GLN A 1 416 ? -52.86520 -33.37070 13.98808  1.000 29.87445  ? 415 GLN A CG  1 
ATOM   3124 C CD  . GLN A 1 416 ? -52.73663 -33.13454 15.47284  1.000 50.95425  ? 415 GLN A CD  1 
ATOM   3125 O OE1 . GLN A 1 416 ? -52.51138 -34.07358 16.24928  1.000 55.11860  ? 415 GLN A OE1 1 
ATOM   3126 N NE2 . GLN A 1 416 ? -52.83998 -31.86719 15.88462  1.000 51.76780  ? 415 GLN A NE2 1 
ATOM   3127 N N   . GLU A 1 417 ? -49.31052 -35.09843 15.11273  1.000 39.46205  ? 416 GLU A N   1 
ATOM   3128 C CA  . GLU A 1 417 ? -48.59964 -35.16194 16.38250  1.000 31.86639  ? 416 GLU A CA  1 
ATOM   3129 C C   . GLU A 1 417 ? -47.23140 -34.52476 16.26021  1.000 33.24846  ? 416 GLU A C   1 
ATOM   3130 O O   . GLU A 1 417 ? -46.84892 -33.68749 17.07989  1.000 33.05304  ? 416 GLU A O   1 
ATOM   3131 C CB  . GLU A 1 417 ? -48.47111 -36.60958 16.83772  1.000 31.03020  ? 416 GLU A CB  1 
ATOM   3132 C CG  . GLU A 1 417 ? -47.58603 -36.78368 18.02271  1.000 33.35970  ? 416 GLU A CG  1 
ATOM   3133 C CD  . GLU A 1 417 ? -48.17313 -36.15372 19.26328  1.000 40.85783  ? 416 GLU A CD  1 
ATOM   3134 O OE1 . GLU A 1 417 ? -49.39506 -35.83315 19.25353  1.000 37.91791  ? 416 GLU A OE1 1 
ATOM   3135 O OE2 . GLU A 1 417 ? -47.40617 -35.97541 20.24322  1.000 42.09268  ? 416 GLU A OE2 1 
ATOM   3136 N N   . TRP A 1 418 ? -46.47333 -34.93009 15.24379  1.000 38.95220  ? 417 TRP A N   1 
ATOM   3137 C CA  . TRP A 1 418 ? -45.21126 -34.27873 14.93080  1.000 33.12558  ? 417 TRP A CA  1 
ATOM   3138 C C   . TRP A 1 418 ? -45.36613 -32.76683 15.00312  1.000 32.61973  ? 417 TRP A C   1 
ATOM   3139 O O   . TRP A 1 418 ? -44.65246 -32.10911 15.76225  1.000 39.44897  ? 417 TRP A O   1 
ATOM   3140 C CB  . TRP A 1 418 ? -44.73155 -34.74199 13.55230  1.000 32.81390  ? 417 TRP A CB  1 
ATOM   3141 C CG  . TRP A 1 418 ? -43.27824 -34.57589 13.31950  1.000 34.46530  ? 417 TRP A CG  1 
ATOM   3142 C CD1 . TRP A 1 418 ? -42.31893 -35.55023 13.31485  1.000 36.74621  ? 417 TRP A CD1 1 
ATOM   3143 C CD2 . TRP A 1 418 ? -42.60588 -33.35394 13.04856  1.000 34.64746  ? 417 TRP A CD2 1 
ATOM   3144 N NE1 . TRP A 1 418 ? -41.08236 -35.00221 13.06475  1.000 29.82112  ? 417 TRP A NE1 1 
ATOM   3145 C CE2 . TRP A 1 418 ? -41.23390 -33.65477 12.89701  1.000 31.42400  ? 417 TRP A CE2 1 
ATOM   3146 C CE3 . TRP A 1 418 ? -43.02825 -32.02369 12.92898  1.000 31.20905  ? 417 TRP A CE3 1 
ATOM   3147 C CZ2 . TRP A 1 418 ? -40.29627 -32.68721 12.62215  1.000 30.70683  ? 417 TRP A CZ2 1 
ATOM   3148 C CZ3 . TRP A 1 418 ? -42.09664 -31.06391 12.65180  1.000 31.18444  ? 417 TRP A CZ3 1 
ATOM   3149 C CH2 . TRP A 1 418 ? -40.74397 -31.39747 12.49582  1.000 31.96611  ? 417 TRP A CH2 1 
ATOM   3150 N N   . LEU A 1 419 ? -46.34569 -32.20446 14.28090  1.000 29.46295  ? 418 LEU A N   1 
ATOM   3151 C CA  . LEU A 1 419 ? -46.56631 -30.75493 14.31421  1.000 29.54115  ? 418 LEU A CA  1 
ATOM   3152 C C   . LEU A 1 419 ? -46.80735 -30.25057 15.73716  1.000 32.09589  ? 418 LEU A C   1 
ATOM   3153 O O   . LEU A 1 419 ? -46.25905 -29.21786 16.13998  1.000 33.51233  ? 418 LEU A O   1 
ATOM   3154 C CB  . LEU A 1 419 ? -47.73864 -30.36322 13.40609  1.000 22.60174  ? 418 LEU A CB  1 
ATOM   3155 C CG  . LEU A 1 419 ? -48.16875 -28.88062 13.38353  1.000 28.23435  ? 418 LEU A CG  1 
ATOM   3156 C CD1 . LEU A 1 419 ? -47.03652 -27.90772 13.04144  1.000 24.36964  ? 418 LEU A CD1 1 
ATOM   3157 C CD2 . LEU A 1 419 ? -49.33081 -28.64763 12.42322  1.000 31.55622  ? 418 LEU A CD2 1 
ATOM   3158 N N   . ALA A 1 420 ? -47.61186 -30.96983 16.52070  1.000 35.69020  ? 419 ALA A N   1 
ATOM   3159 C CA  . ALA A 1 420 ? -47.92059 -30.50379 17.86996  1.000 33.90085  ? 419 ALA A CA  1 
ATOM   3160 C C   . ALA A 1 420 ? -46.66599 -30.42945 18.72844  1.000 38.63032  ? 419 ALA A C   1 
ATOM   3161 O O   . ALA A 1 420 ? -46.48337 -29.46520 19.48507  1.000 40.76869  ? 419 ALA A O   1 
ATOM   3162 C CB  . ALA A 1 420 ? -48.96169 -31.40604 18.51854  1.000 26.83615  ? 419 ALA A CB  1 
ATOM   3163 N N   . ARG A 1 421 ? -45.78697 -31.43625 18.61866  1.000 35.90919  ? 420 ARG A N   1 
ATOM   3164 C CA  . ARG A 1 421 ? -44.54860 -31.43092 19.38569  1.000 30.41630  ? 420 ARG A CA  1 
ATOM   3165 C C   . ARG A 1 421 ? -43.60345 -30.36288 18.86850  1.000 39.70059  ? 420 ARG A C   1 
ATOM   3166 O O   . ARG A 1 421 ? -42.86088 -29.75075 19.65086  1.000 42.87540  ? 420 ARG A O   1 
ATOM   3167 C CB  . ARG A 1 421 ? -43.87232 -32.79133 19.32435  1.000 26.95244  ? 420 ARG A CB  1 
ATOM   3168 C CG  . ARG A 1 421 ? -44.64599 -33.87887 19.96776  1.000 31.63039  ? 420 ARG A CG  1 
ATOM   3169 C CD  . ARG A 1 421 ? -43.75551 -35.07053 20.11607  1.000 38.61035  ? 420 ARG A CD  1 
ATOM   3170 N NE  . ARG A 1 421 ? -44.45355 -36.24438 20.62122  1.000 35.85221  ? 420 ARG A NE  1 
ATOM   3171 C CZ  . ARG A 1 421 ? -43.84655 -37.39152 20.88619  1.000 41.03653  ? 420 ARG A CZ  1 
ATOM   3172 N NH1 . ARG A 1 421 ? -42.54149 -37.53771 20.70275  1.000 49.23852  ? 420 ARG A NH1 1 
ATOM   3173 N NH2 . ARG A 1 421 ? -44.56261 -38.41648 21.34335  1.000 42.10627  ? 420 ARG A NH2 1 
ATOM   3174 N N   . TYR A 1 422 ? -43.60231 -30.13167 17.55066  1.000 35.22069  ? 421 TYR A N   1 
ATOM   3175 C CA  . TYR A 1 422 ? -42.81154 -29.03323 17.00530  1.000 33.71163  ? 421 TYR A CA  1 
ATOM   3176 C C   . TYR A 1 422 ? -43.24031 -27.70739 17.62309  1.000 38.45412  ? 421 TYR A C   1 
ATOM   3177 O O   . TYR A 1 422 ? -42.40211 -26.92072 18.08781  1.000 36.84099  ? 421 TYR A O   1 
ATOM   3178 C CB  . TYR A 1 422 ? -42.95330 -28.99764 15.48867  1.000 32.53280  ? 421 TYR A CB  1 
ATOM   3179 C CG  . TYR A 1 422 ? -42.55689 -27.69513 14.83371  1.000 32.05969  ? 421 TYR A CG  1 
ATOM   3180 C CD1 . TYR A 1 422 ? -41.31422 -27.11370 15.06299  1.000 28.15802  ? 421 TYR A CD1 1 
ATOM   3181 C CD2 . TYR A 1 422 ? -43.42378 -27.06337 13.95254  1.000 34.37803  ? 421 TYR A CD2 1 
ATOM   3182 C CE1 . TYR A 1 422 ? -40.95451 -25.92802 14.42922  1.000 32.05836  ? 421 TYR A CE1 1 
ATOM   3183 C CE2 . TYR A 1 422 ? -43.08202 -25.87588 13.32726  1.000 30.90952  ? 421 TYR A CE2 1 
ATOM   3184 C CZ  . TYR A 1 422 ? -41.85268 -25.31720 13.55955  1.000 33.47323  ? 421 TYR A CZ  1 
ATOM   3185 O OH  . TYR A 1 422 ? -41.54477 -24.13816 12.91543  1.000 38.53531  ? 421 TYR A OH  1 
ATOM   3186 N N   . LEU A 1 423 ? -44.55495 -27.46589 17.68184  1.000 32.49042  ? 422 LEU A N   1 
ATOM   3187 C CA  . LEU A 1 423 ? -45.03685 -26.18102 18.16956  1.000 35.12754  ? 422 LEU A CA  1 
ATOM   3188 C C   . LEU A 1 423 ? -44.67363 -25.97025 19.64331  1.000 40.71815  ? 422 LEU A C   1 
ATOM   3189 O O   . LEU A 1 423 ? -44.19613 -24.88858 20.02251  1.000 37.38200  ? 422 LEU A O   1 
ATOM   3190 C CB  . LEU A 1 423 ? -46.54281 -26.07433 17.92472  1.000 37.10155  ? 422 LEU A CB  1 
ATOM   3191 C CG  . LEU A 1 423 ? -46.97330 -25.90534 16.45535  1.000 33.14850  ? 422 LEU A CG  1 
ATOM   3192 C CD1 . LEU A 1 423 ? -48.48585 -25.78832 16.33069  1.000 36.57929  ? 422 LEU A CD1 1 
ATOM   3193 C CD2 . LEU A 1 423 ? -46.32145 -24.68872 15.82410  1.000 30.13898  ? 422 LEU A CD2 1 
ATOM   3194 N N   . ARG A 1 424 ? -44.86600 -26.99947 20.48360  1.000 39.54886  ? 423 ARG A N   1 
ATOM   3195 C CA  . ARG A 1 424 ? -44.37031 -26.94205 21.85705  1.000 35.50382  ? 423 ARG A CA  1 
ATOM   3196 C C   . ARG A 1 424 ? -42.88585 -26.62972 21.90318  1.000 36.80564  ? 423 ARG A C   1 
ATOM   3197 O O   . ARG A 1 424 ? -42.43367 -25.87725 22.76948  1.000 39.11086  ? 423 ARG A O   1 
ATOM   3198 C CB  . ARG A 1 424 ? -44.64382 -28.25375 22.58377  1.000 34.27809  ? 423 ARG A CB  1 
ATOM   3199 C CG  . ARG A 1 424 ? -46.10452 -28.46230 22.82019  1.000 38.09448  ? 423 ARG A CG  1 
ATOM   3200 C CD  . ARG A 1 424 ? -46.37236 -29.58804 23.75493  1.000 34.31612  ? 423 ARG A CD  1 
ATOM   3201 N NE  . ARG A 1 424 ? -47.30937 -30.52588 23.15131  1.000 41.24611  ? 423 ARG A NE  1 
ATOM   3202 C CZ  . ARG A 1 424 ? -46.98866 -31.74694 22.73939  1.000 41.67727  ? 423 ARG A CZ  1 
ATOM   3203 N NH1 . ARG A 1 424 ? -45.77043 -32.25236 22.93311  1.000 37.31088  ? 423 ARG A NH1 1 
ATOM   3204 N NH2 . ARG A 1 424 ? -47.91564 -32.48678 22.13311  1.000 37.99415  ? 423 ARG A NH2 1 
ATOM   3205 N N   . ALA A 1 425 ? -42.10535 -27.17381 20.97008  1.000 37.40613  ? 424 ALA A N   1 
ATOM   3206 C CA  . ALA A 1 425 ? -40.66370 -26.98516 21.08734  1.000 37.35400  ? 424 ALA A CA  1 
ATOM   3207 C C   . ALA A 1 425 ? -40.22518 -25.59238 20.67033  1.000 37.69521  ? 424 ALA A C   1 
ATOM   3208 O O   . ALA A 1 425 ? -39.19329 -25.11438 21.15041  1.000 35.38834  ? 424 ALA A O   1 
ATOM   3209 C CB  . ALA A 1 425 ? -39.92086 -28.02821 20.26533  1.000 30.85452  ? 424 ALA A CB  1 
ATOM   3210 N N   . TYR A 1 426 ? -40.99673 -24.92694 19.80366  1.000 38.77585  ? 425 TYR A N   1 
ATOM   3211 C CA  . TYR A 1 426 ? -40.58803 -23.67312 19.17740  1.000 35.75757  ? 425 TYR A CA  1 
ATOM   3212 C C   . TYR A 1 426 ? -41.57337 -22.53679 19.41216  1.000 35.95214  ? 425 TYR A C   1 
ATOM   3213 O O   . TYR A 1 426 ? -41.16786 -21.46461 19.87429  1.000 36.72115  ? 425 TYR A O   1 
ATOM   3214 C CB  . TYR A 1 426 ? -40.36580 -23.90800 17.66571  1.000 32.36978  ? 425 TYR A CB  1 
ATOM   3215 C CG  . TYR A 1 426 ? -40.61314 -22.71804 16.76324  1.000 30.73351  ? 425 TYR A CG  1 
ATOM   3216 C CD1 . TYR A 1 426 ? -39.67476 -21.70464 16.64376  1.000 36.19770  ? 425 TYR A CD1 1 
ATOM   3217 C CD2 . TYR A 1 426 ? -41.77766 -22.62479 16.00597  1.000 32.25800  ? 425 TYR A CD2 1 
ATOM   3218 C CE1 . TYR A 1 426 ? -39.90129 -20.61083 15.81027  1.000 37.79727  ? 425 TYR A CE1 1 
ATOM   3219 C CE2 . TYR A 1 426 ? -42.00913 -21.55266 15.16816  1.000 32.21123  ? 425 TYR A CE2 1 
ATOM   3220 C CZ  . TYR A 1 426 ? -41.06908 -20.54866 15.07867  1.000 37.41528  ? 425 TYR A CZ  1 
ATOM   3221 O OH  . TYR A 1 426 ? -41.30357 -19.47318 14.26310  1.000 41.62385  ? 425 TYR A OH  1 
ATOM   3222 N N   . LEU A 1 427 ? -42.86022 -22.72495 19.10932  1.000 33.21225  ? 426 LEU A N   1 
ATOM   3223 C CA  . LEU A 1 427 ? -43.80720 -21.62805 19.29207  1.000 33.03960  ? 426 LEU A CA  1 
ATOM   3224 C C   . LEU A 1 427 ? -43.99806 -21.31409 20.77313  1.000 36.57162  ? 426 LEU A C   1 
ATOM   3225 O O   . LEU A 1 427 ? -44.08949 -20.14430 21.16049  1.000 34.74142  ? 426 LEU A O   1 
ATOM   3226 C CB  . LEU A 1 427 ? -45.14771 -21.96510 18.62347  1.000 32.70904  ? 426 LEU A CB  1 
ATOM   3227 C CG  . LEU A 1 427 ? -46.37454 -21.04142 18.72833  1.000 26.33849  ? 426 LEU A CG  1 
ATOM   3228 C CD1 . LEU A 1 427 ? -46.09391 -19.67072 18.15623  1.000 27.68244  ? 426 LEU A CD1 1 
ATOM   3229 C CD2 . LEU A 1 427 ? -47.58084 -21.65674 18.04503  1.000 22.85625  ? 426 LEU A CD2 1 
ATOM   3230 N N   . HIS A 1 428 ? -44.03309 -22.33869 21.62009  1.000 37.25668  ? 427 HIS A N   1 
ATOM   3231 C CA  . HIS A 1 428 ? -44.30757 -22.08926 23.03113  1.000 35.74763  ? 427 HIS A CA  1 
ATOM   3232 C C   . HIS A 1 428 ? -43.23997 -21.23408 23.70057  1.000 37.48190  ? 427 HIS A C   1 
ATOM   3233 O O   . HIS A 1 428 ? -43.60464 -20.22733 24.33399  1.000 39.96378  ? 427 HIS A O   1 
ATOM   3234 C CB  . HIS A 1 428 ? -44.53704 -23.41638 23.74896  1.000 30.59348  ? 427 HIS A CB  1 
ATOM   3235 C CG  . HIS A 1 428 ? -45.89524 -23.97750 23.50800  1.000 36.49108  ? 427 HIS A CG  1 
ATOM   3236 N ND1 . HIS A 1 428 ? -46.46828 -24.92881 24.32177  1.000 40.41684  ? 427 HIS A ND1 1 
ATOM   3237 C CD2 . HIS A 1 428 ? -46.80935 -23.70052 22.54813  1.000 35.97386  ? 427 HIS A CD2 1 
ATOM   3238 C CE1 . HIS A 1 428 ? -47.67080 -25.22936 23.86025  1.000 39.19330  ? 427 HIS A CE1 1 
ATOM   3239 N NE2 . HIS A 1 428 ? -47.90439 -24.49238 22.78775  1.000 34.38777  ? 427 HIS A NE2 1 
ATOM   3240 N N   . PRO A 1 429 ? -41.94142 -21.53076 23.60449  1.000 35.51768  ? 428 PRO A N   1 
ATOM   3241 C CA  . PRO A 1 429 ? -40.98054 -20.61725 24.23270  1.000 32.76441  ? 428 PRO A CA  1 
ATOM   3242 C C   . PRO A 1 429 ? -41.01695 -19.22428 23.62989  1.000 34.96827  ? 428 PRO A C   1 
ATOM   3243 O O   . PRO A 1 429 ? -40.83764 -18.24539 24.36420  1.000 39.28084  ? 428 PRO A O   1 
ATOM   3244 C CB  . PRO A 1 429 ? -39.62719 -21.31584 24.02053  1.000 35.05053  ? 428 PRO A CB  1 
ATOM   3245 C CG  . PRO A 1 429 ? -39.84237 -22.27122 22.93510  1.000 35.84935  ? 428 PRO A CG  1 
ATOM   3246 C CD  . PRO A 1 429 ? -41.26891 -22.71187 23.03272  1.000 37.21864  ? 428 PRO A CD  1 
ATOM   3247 N N   . ILE A 1 430 ? -41.29170 -19.09209 22.32976  1.000 33.36078  ? 429 ILE A N   1 
ATOM   3248 C CA  . ILE A 1 430 ? -41.34531 -17.76206 21.72422  1.000 29.50550  ? 429 ILE A CA  1 
ATOM   3249 C C   . ILE A 1 430 ? -42.45426 -16.94276 22.35635  1.000 28.47962  ? 429 ILE A C   1 
ATOM   3250 O O   . ILE A 1 430 ? -42.24469 -15.79923 22.76120  1.000 37.93619  ? 429 ILE A O   1 
ATOM   3251 C CB  . ILE A 1 430 ? -41.51569 -17.85495 20.19577  1.000 33.16570  ? 429 ILE A CB  1 
ATOM   3252 C CG1 . ILE A 1 430 ? -40.20529 -18.29259 19.52384  1.000 30.36507  ? 429 ILE A CG1 1 
ATOM   3253 C CG2 . ILE A 1 430 ? -42.03870 -16.53511 19.60980  1.000 28.25289  ? 429 ILE A CG2 1 
ATOM   3254 C CD1 . ILE A 1 430 ? -38.98264 -17.55415 20.00895  1.000 29.64612  ? 429 ILE A CD1 1 
ATOM   3255 N N   . ILE A 1 431 ? -43.65498 -17.50852 22.43800  1.000 33.52856  ? 430 ILE A N   1 
ATOM   3256 C CA  . ILE A 1 431 ? -44.74931 -16.83516 23.13370  1.000 37.52556  ? 430 ILE A CA  1 
ATOM   3257 C C   . ILE A 1 431 ? -44.30426 -16.44542 24.53886  1.000 39.58477  ? 430 ILE A C   1 
ATOM   3258 O O   . ILE A 1 431 ? -44.28893 -15.26310 24.90533  1.000 41.86892  ? 430 ILE A O   1 
ATOM   3259 C CB  . ILE A 1 431 ? -45.99948 -17.73248 23.18423  1.000 35.96234  ? 430 ILE A CB  1 
ATOM   3260 C CG1 . ILE A 1 431 ? -46.49827 -18.07441 21.79274  1.000 35.17867  ? 430 ILE A CG1 1 
ATOM   3261 C CG2 . ILE A 1 431 ? -47.11945 -17.03645 23.90903  1.000 31.16172  ? 430 ILE A CG2 1 
ATOM   3262 C CD1 . ILE A 1 431 ? -47.77290 -18.88235 21.83855  1.000 30.08438  ? 430 ILE A CD1 1 
ATOM   3263 N N   . TYR A 1 432 ? -43.92487 -17.44481 25.33910  1.000 32.78423  ? 431 TYR A N   1 
ATOM   3264 C CA  . TYR A 1 432 ? -43.57690 -17.19954 26.73221  1.000 36.36694  ? 431 TYR A CA  1 
ATOM   3265 C C   . TYR A 1 432 ? -42.62211 -16.02382 26.86118  1.000 40.49813  ? 431 TYR A C   1 
ATOM   3266 O O   . TYR A 1 432 ? -42.83078 -15.12471 27.68181  1.000 44.52545  ? 431 TYR A O   1 
ATOM   3267 C CB  . TYR A 1 432 ? -42.96758 -18.46067 27.33509  1.000 36.28553  ? 431 TYR A CB  1 
ATOM   3268 C CG  . TYR A 1 432 ? -42.59217 -18.36515 28.79205  1.000 40.09991  ? 431 TYR A CG  1 
ATOM   3269 C CD1 . TYR A 1 432 ? -43.56503 -18.28844 29.79079  1.000 39.63846  ? 431 TYR A CD1 1 
ATOM   3270 C CD2 . TYR A 1 432 ? -41.25604 -18.38886 29.17813  1.000 46.67087  ? 431 TYR A CD2 1 
ATOM   3271 C CE1 . TYR A 1 432 ? -43.20862 -18.23149 31.13862  1.000 37.83610  ? 431 TYR A CE1 1 
ATOM   3272 C CE2 . TYR A 1 432 ? -40.88388 -18.32487 30.52295  1.000 45.30300  ? 431 TYR A CE2 1 
ATOM   3273 C CZ  . TYR A 1 432 ? -41.86126 -18.24744 31.49361  1.000 44.34118  ? 431 TYR A CZ  1 
ATOM   3274 O OH  . TYR A 1 432 ? -41.46847 -18.18571 32.80855  1.000 45.79867  ? 431 TYR A OH  1 
ATOM   3275 N N   . LEU A 1 433 ? -41.58523 -15.99669 26.02468  1.000 38.04300  ? 432 LEU A N   1 
ATOM   3276 C CA  . LEU A 1 433 ? -40.61890 -14.90873 26.07673  1.000 33.93418  ? 432 LEU A CA  1 
ATOM   3277 C C   . LEU A 1 433 ? -41.26533 -13.56932 25.78172  1.000 37.54213  ? 432 LEU A C   1 
ATOM   3278 O O   . LEU A 1 433 ? -40.82428 -12.54107 26.29525  1.000 41.73049  ? 432 LEU A O   1 
ATOM   3279 C CB  . LEU A 1 433 ? -39.49268 -15.17498 25.08940  1.000 32.37266  ? 432 LEU A CB  1 
ATOM   3280 C CG  . LEU A 1 433 ? -38.43777 -16.15630 25.57475  1.000 36.27034  ? 432 LEU A CG  1 
ATOM   3281 C CD1 . LEU A 1 433 ? -37.67313 -16.68428 24.39196  1.000 37.94280  ? 432 LEU A CD1 1 
ATOM   3282 C CD2 . LEU A 1 433 ? -37.49667 -15.47944 26.54409  1.000 35.68748  ? 432 LEU A CD2 1 
ATOM   3283 N N   . LEU A 1 434 ? -42.29393 -13.54644 24.94986  1.000 36.58566  ? 433 LEU A N   1 
ATOM   3284 C CA  . LEU A 1 434 ? -42.91528 -12.26988 24.65135  1.000 37.45109  ? 433 LEU A CA  1 
ATOM   3285 C C   . LEU A 1 434 ? -43.90903 -11.86429 25.73461  1.000 43.47811  ? 433 LEU A C   1 
ATOM   3286 O O   . LEU A 1 434 ? -44.03893 -10.67298 26.04574  1.000 46.01486  ? 433 LEU A O   1 
ATOM   3287 C CB  . LEU A 1 434 ? -43.59709 -12.33732 23.29009  1.000 34.81387  ? 433 LEU A CB  1 
ATOM   3288 C CG  . LEU A 1 434 ? -44.16711 -11.01194 22.80948  1.000 31.75244  ? 433 LEU A CG  1 
ATOM   3289 C CD1 . LEU A 1 434 ? -43.11537 -9.91753  22.88785  1.000 37.07972  ? 433 LEU A CD1 1 
ATOM   3290 C CD2 . LEU A 1 434 ? -44.65579 -11.17756 21.41926  1.000 33.44849  ? 433 LEU A CD2 1 
ATOM   3291 N N   . TYR A 1 435 ? -44.60652 -12.83034 26.32743  1.000 42.17453  ? 434 TYR A N   1 
ATOM   3292 C CA  . TYR A 1 435 ? -45.62829 -12.51451 27.31367  1.000 40.22578  ? 434 TYR A CA  1 
ATOM   3293 C C   . TYR A 1 435 ? -45.07728 -12.49709 28.72984  1.000 43.74151  ? 434 TYR A C   1 
ATOM   3294 O O   . TYR A 1 435 ? -45.42962 -11.61183 29.51689  1.000 46.53596  ? 434 TYR A O   1 
ATOM   3295 C CB  . TYR A 1 435 ? -46.78835 -13.50089 27.18664  1.000 41.79937  ? 434 TYR A CB  1 
ATOM   3296 C CG  . TYR A 1 435 ? -47.66538 -13.13128 26.01501  1.000 43.55784  ? 434 TYR A CG  1 
ATOM   3297 C CD1 . TYR A 1 435 ? -47.31384 -13.49933 24.72715  1.000 39.34989  ? 434 TYR A CD1 1 
ATOM   3298 C CD2 . TYR A 1 435 ? -48.81754 -12.37156 26.18822  1.000 45.45163  ? 434 TYR A CD2 1 
ATOM   3299 C CE1 . TYR A 1 435 ? -48.09438 -13.13665 23.63657  1.000 41.06801  ? 434 TYR A CE1 1 
ATOM   3300 C CE2 . TYR A 1 435 ? -49.61238 -12.00664 25.10169  1.000 48.61792  ? 434 TYR A CE2 1 
ATOM   3301 C CZ  . TYR A 1 435 ? -49.24187 -12.39474 23.82114  1.000 45.57948  ? 434 TYR A CZ  1 
ATOM   3302 O OH  . TYR A 1 435 ? -50.01155 -12.05105 22.72437  1.000 40.08343  ? 434 TYR A OH  1 
ATOM   3303 N N   . ARG A 1 436 ? -44.19455 -13.42936 29.07578  1.000 40.62761  ? 435 ARG A N   1 
ATOM   3304 C CA  . ARG A 1 436 ? -43.61004 -13.36259 30.40891  1.000 44.45405  ? 435 ARG A CA  1 
ATOM   3305 C C   . ARG A 1 436 ? -42.56577 -12.25450 30.51080  1.000 42.41097  ? 435 ARG A C   1 
ATOM   3306 O O   . ARG A 1 436 ? -42.55188 -11.50192 31.48761  1.000 45.49930  ? 435 ARG A O   1 
ATOM   3307 C CB  . ARG A 1 436 ? -43.00529 -14.71433 30.78926  1.000 45.66809  ? 435 ARG A CB  1 
ATOM   3308 C CG  . ARG A 1 436 ? -42.19083 -14.69543 32.06645  1.000 40.74871  ? 435 ARG A CG  1 
ATOM   3309 C CD  . ARG A 1 436 ? -43.02727 -14.21834 33.21055  1.000 41.28264  ? 435 ARG A CD  1 
ATOM   3310 N NE  . ARG A 1 436 ? -42.27057 -14.16323 34.45957  1.000 54.39641  ? 435 ARG A NE  1 
ATOM   3311 C CZ  . ARG A 1 436 ? -41.44991 -13.17873 34.80980  1.000 53.42063  ? 435 ARG A CZ  1 
ATOM   3312 N NH1 . ARG A 1 436 ? -41.15821 -12.18711 33.97625  1.000 47.74841  ? 435 ARG A NH1 1 
ATOM   3313 N NH2 . ARG A 1 436 ? -40.92429 -13.17786 36.03413  1.000 47.80108  ? 435 ARG A NH2 1 
ATOM   3314 N N   . TYR A 1 437 ? -41.69172 -12.12884 29.51912  1.000 41.03266  ? 436 TYR A N   1 
ATOM   3315 C CA  . TYR A 1 437 ? -40.54605 -11.23573 29.61889  1.000 40.67994  ? 436 TYR A CA  1 
ATOM   3316 C C   . TYR A 1 437 ? -40.60731 -10.03579 28.68412  1.000 41.29704  ? 436 TYR A C   1 
ATOM   3317 O O   . TYR A 1 437 ? -39.77034 -9.14375  28.81383  1.000 44.13631  ? 436 TYR A O   1 
ATOM   3318 C CB  . TYR A 1 437 ? -39.24432 -12.01095 29.34779  1.000 41.31183  ? 436 TYR A CB  1 
ATOM   3319 C CG  . TYR A 1 437 ? -38.83981 -12.98388 30.45213  1.000 46.90229  ? 436 TYR A CG  1 
ATOM   3320 C CD1 . TYR A 1 437 ? -38.86449 -12.60622 31.78678  1.000 46.68675  ? 436 TYR A CD1 1 
ATOM   3321 C CD2 . TYR A 1 437 ? -38.42780 -14.27142 30.15648  1.000 45.01395  ? 436 TYR A CD2 1 
ATOM   3322 C CE1 . TYR A 1 437 ? -38.48473 -13.47442 32.78623  1.000 46.50076  ? 436 TYR A CE1 1 
ATOM   3323 C CE2 . TYR A 1 437 ? -38.05153 -15.15450 31.16061  1.000 48.90975  ? 436 TYR A CE2 1 
ATOM   3324 C CZ  . TYR A 1 437 ? -38.07787 -14.74977 32.47658  1.000 49.74292  ? 436 TYR A CZ  1 
ATOM   3325 O OH  . TYR A 1 437 ? -37.70617 -15.62218 33.49249  1.000 50.29128  ? 436 TYR A OH  1 
ATOM   3326 N N   . GLU A 1 438 ? -41.56132 -9.98344  27.75232  1.000 39.61823  ? 437 GLU A N   1 
ATOM   3327 C CA  . GLU A 1 438 ? -41.63560 -8.90849  26.76523  1.000 41.47978  ? 437 GLU A CA  1 
ATOM   3328 C C   . GLU A 1 438 ? -40.33160 -8.77923  25.96333  1.000 49.50535  ? 437 GLU A C   1 
ATOM   3329 O O   . GLU A 1 438 ? -39.75693 -7.69249  25.83337  1.000 43.47236  ? 437 GLU A O   1 
ATOM   3330 C CB  . GLU A 1 438 ? -42.02058 -7.59860  27.44455  1.000 41.75529  ? 437 GLU A CB  1 
ATOM   3331 C CG  . GLU A 1 438 ? -43.06632 -7.82905  28.52434  1.000 47.55738  ? 437 GLU A CG  1 
ATOM   3332 C CD  . GLU A 1 438 ? -43.89250 -6.59934  28.87500  1.000 57.68897  ? 437 GLU A CD  1 
ATOM   3333 O OE1 . GLU A 1 438 ? -44.09096 -5.71922  28.00683  1.000 64.31605  ? 437 GLU A OE1 1 
ATOM   3334 O OE2 . GLU A 1 438 ? -44.36513 -6.52704  30.02668  1.000 57.67903  ? 437 GLU A OE2 1 
ATOM   3335 N N   . PHE A 1 439 ? -39.86950 -9.91657  25.42243  1.000 46.26044  ? 438 PHE A N   1 
ATOM   3336 C CA  . PHE A 1 439 ? -38.75428 -9.99028  24.48252  1.000 40.62838  ? 438 PHE A CA  1 
ATOM   3337 C C   . PHE A 1 439 ? -39.27706 -10.44687 23.13458  1.000 44.58587  ? 438 PHE A C   1 
ATOM   3338 O O   . PHE A 1 439 ? -40.00006 -11.44542 23.05465  1.000 50.99624  ? 438 PHE A O   1 
ATOM   3339 C CB  . PHE A 1 439 ? -37.68806 -11.00044 24.90477  1.000 44.61383  ? 438 PHE A CB  1 
ATOM   3340 C CG  . PHE A 1 439 ? -36.96663 -10.65950 26.15707  1.000 50.92554  ? 438 PHE A CG  1 
ATOM   3341 C CD1 . PHE A 1 439 ? -36.94230 -9.36566  26.64006  1.000 51.43858  ? 438 PHE A CD1 1 
ATOM   3342 C CD2 . PHE A 1 439 ? -36.29319 -11.65511 26.85966  1.000 50.85930  ? 438 PHE A CD2 1 
ATOM   3343 C CE1 . PHE A 1 439 ? -36.25802 -9.07516  27.80940  1.000 49.73333  ? 438 PHE A CE1 1 
ATOM   3344 C CE2 . PHE A 1 439 ? -35.61646 -11.37617 28.02523  1.000 40.37539  ? 438 PHE A CE2 1 
ATOM   3345 C CZ  . PHE A 1 439 ? -35.59061 -10.08774 28.49647  1.000 44.86308  ? 438 PHE A CZ  1 
ATOM   3346 N N   . LYS A 1 440 ? -38.88109 -9.75037  22.08126  1.000 47.46405  ? 439 LYS A N   1 
ATOM   3347 C CA  . LYS A 1 440 ? -39.12403 -10.17297 20.71042  1.000 42.17353  ? 439 LYS A CA  1 
ATOM   3348 C C   . LYS A 1 440 ? -37.76952 -10.42039 20.05439  1.000 46.62258  ? 439 LYS A C   1 
ATOM   3349 O O   . LYS A 1 440 ? -36.82451 -9.65764  20.27256  1.000 49.23379  ? 439 LYS A O   1 
ATOM   3350 C CB  . LYS A 1 440 ? -39.92756 -9.10667  19.95794  1.000 37.36653  ? 439 LYS A CB  1 
ATOM   3351 C CG  . LYS A 1 440 ? -40.68014 -9.61574  18.76688  1.000 48.08268  ? 439 LYS A CG  1 
ATOM   3352 C CD  . LYS A 1 440 ? -41.05903 -8.50698  17.79533  1.000 48.29426  ? 439 LYS A CD  1 
ATOM   3353 C CE  . LYS A 1 440 ? -39.84791 -7.99938  17.03604  1.000 55.35887  ? 439 LYS A CE  1 
ATOM   3354 N NZ  . LYS A 1 440 ? -38.92501 -9.10141  16.61657  1.000 55.22029  ? 439 LYS A NZ  1 
ATOM   3355 N N   . PHE A 1 441 ? -37.64415 -11.51025 19.29734  1.000 45.43729  ? 440 PHE A N   1 
ATOM   3356 C CA  . PHE A 1 441 ? -36.38380 -11.76180 18.60007  1.000 44.29839  ? 440 PHE A CA  1 
ATOM   3357 C C   . PHE A 1 441 ? -36.60156 -11.80606 17.09140  1.000 44.35813  ? 440 PHE A C   1 
ATOM   3358 O O   . PHE A 1 441 ? -37.36319 -10.99145 16.55889  1.000 52.51913  ? 440 PHE A O   1 
ATOM   3359 C CB  . PHE A 1 441 ? -35.73036 -13.05341 19.09165  1.000 42.17850  ? 440 PHE A CB  1 
ATOM   3360 C CG  . PHE A 1 441 ? -35.27106 -12.99997 20.51972  1.000 39.80474  ? 440 PHE A CG  1 
ATOM   3361 C CD1 . PHE A 1 441 ? -34.06231 -12.41633 20.84968  1.000 46.57636  ? 440 PHE A CD1 1 
ATOM   3362 C CD2 . PHE A 1 441 ? -36.03048 -13.56688 21.53294  1.000 44.14032  ? 440 PHE A CD2 1 
ATOM   3363 C CE1 . PHE A 1 441 ? -33.62234 -12.38764 22.19096  1.000 52.59372  ? 440 PHE A CE1 1 
ATOM   3364 C CE2 . PHE A 1 441 ? -35.60562 -13.54621 22.86066  1.000 41.06630  ? 440 PHE A CE2 1 
ATOM   3365 C CZ  . PHE A 1 441 ? -34.40020 -12.95265 23.18905  1.000 45.19840  ? 440 PHE A CZ  1 
ATOM   3366 N N   . SER A 1 442 ? -35.93038 -12.72626 16.38850  1.000 43.27493  ? 441 SER A N   1 
ATOM   3367 C CA  . SER A 1 442 ? -36.19894 -13.00274 14.96887  1.000 46.00101  ? 441 SER A CA  1 
ATOM   3368 C C   . SER A 1 442 ? -36.31843 -14.50954 14.78727  1.000 42.02246  ? 441 SER A C   1 
ATOM   3369 O O   . SER A 1 442 ? -35.38793 -15.17013 14.30085  1.000 39.43376  ? 441 SER A O   1 
ATOM   3370 C CB  . SER A 1 442 ? -35.11759 -12.43272 14.04979  1.000 41.30299  ? 441 SER A CB  1 
ATOM   3371 O OG  . SER A 1 442 ? -35.09914 -11.01896 14.09500  1.000 46.27447  ? 441 SER A OG  1 
ATOM   3372 N N   . PRO A 1 443 ? -37.46468 -15.07971 15.13702  1.000 36.77068  ? 442 PRO A N   1 
ATOM   3373 C CA  . PRO A 1 443 ? -37.62580 -16.53640 15.21128  1.000 41.22235  ? 442 PRO A CA  1 
ATOM   3374 C C   . PRO A 1 443 ? -37.85805 -17.20742 13.85740  1.000 43.32707  ? 442 PRO A C   1 
ATOM   3375 O O   . PRO A 1 443 ? -38.81457 -17.96070 13.67165  1.000 42.11667  ? 442 PRO A O   1 
ATOM   3376 C CB  . PRO A 1 443 ? -38.84995 -16.68846 16.11918  1.000 38.87618  ? 442 PRO A CB  1 
ATOM   3377 C CG  . PRO A 1 443 ? -39.68138 -15.46569 15.80236  1.000 40.59735  ? 442 PRO A CG  1 
ATOM   3378 C CD  . PRO A 1 443 ? -38.75875 -14.38899 15.25379  1.000 40.45485  ? 442 PRO A CD  1 
ATOM   3379 N N   . HIS A 1 444 ? -36.97494 -16.93808 12.90429  1.000 46.21264  ? 443 HIS A N   1 
ATOM   3380 C CA  . HIS A 1 444 ? -37.12977 -17.46681 11.55919  1.000 40.79859  ? 443 HIS A CA  1 
ATOM   3381 C C   . HIS A 1 444 ? -36.16399 -18.62206 11.32669  1.000 39.16290  ? 443 HIS A C   1 
ATOM   3382 O O   . HIS A 1 444 ? -35.30346 -18.92792 12.15840  1.000 40.80715  ? 443 HIS A O   1 
ATOM   3383 C CB  . HIS A 1 444 ? -36.96071 -16.35578 10.51880  1.000 39.52668  ? 443 HIS A CB  1 
ATOM   3384 C CG  . HIS A 1 444 ? -35.62384 -15.68664 10.52570  1.000 39.17372  ? 443 HIS A CG  1 
ATOM   3385 N ND1 . HIS A 1 444 ? -35.49078 -14.31430 10.49906  1.000 44.34800  ? 443 HIS A ND1 1 
ATOM   3386 C CD2 . HIS A 1 444 ? -34.36712 -16.18665 10.44513  1.000 43.29380  ? 443 HIS A CD2 1 
ATOM   3387 C CE1 . HIS A 1 444 ? -34.20808 -13.99640 10.46331  1.000 44.66944  ? 443 HIS A CE1 1 
ATOM   3388 N NE2 . HIS A 1 444 ? -33.50424 -15.11409 10.42094  1.000 46.60466  ? 443 HIS A NE2 1 
ATOM   3389 N N   . GLY A 1 445 ? -36.33861 -19.27842 10.18241  1.000 35.50510  ? 444 GLY A N   1 
ATOM   3390 C CA  . GLY A 1 445 ? -35.69607 -20.56324 9.97376   1.000 33.07095  ? 444 GLY A CA  1 
ATOM   3391 C C   . GLY A 1 445 ? -34.21294 -20.58117 10.27005  1.000 35.51688  ? 444 GLY A C   1 
ATOM   3392 O O   . GLY A 1 445 ? -33.69041 -21.58277 10.75725  1.000 41.84117  ? 444 GLY A O   1 
ATOM   3393 N N   . GLU A 1 446 ? -33.51177 -19.48055 9.99447   1.000 38.12666  ? 445 GLU A N   1 
ATOM   3394 C CA  . GLU A 1 446 ? -32.06976 -19.47634 10.20456  1.000 38.56443  ? 445 GLU A CA  1 
ATOM   3395 C C   . GLU A 1 446 ? -31.70220 -19.40903 11.67856  1.000 42.04076  ? 445 GLU A C   1 
ATOM   3396 O O   . GLU A 1 446 ? -30.67402 -19.96263 12.08293  1.000 47.85821  ? 445 GLU A O   1 
ATOM   3397 C CB  . GLU A 1 446 ? -31.42363 -18.30199 9.48724   1.000 46.59141  ? 445 GLU A CB  1 
ATOM   3398 C CG  . GLU A 1 446 ? -31.05015 -18.53037 8.04379   1.000 48.23740  ? 445 GLU A CG  1 
ATOM   3399 C CD  . GLU A 1 446 ? -30.46244 -17.26726 7.41711   1.000 60.93846  ? 445 GLU A CD  1 
ATOM   3400 O OE1 . GLU A 1 446 ? -30.19757 -16.29189 8.18488   1.000 56.29143  ? 445 GLU A OE1 1 
ATOM   3401 O OE2 . GLU A 1 446 ? -30.29106 -17.24626 6.16403   1.000 64.13314  ? 445 GLU A OE2 1 
ATOM   3402 N N   . ASN A 1 447 ? -32.50479 -18.73218 12.48968  1.000 39.54939  ? 446 ASN A N   1 
ATOM   3403 C CA  . ASN A 1 447 ? -32.14275 -18.46453 13.87776  1.000 43.62553  ? 446 ASN A CA  1 
ATOM   3404 C C   . ASN A 1 447 ? -32.64639 -19.51985 14.86558  1.000 41.72623  ? 446 ASN A C   1 
ATOM   3405 O O   . ASN A 1 447 ? -32.40264 -19.38220 16.07222  1.000 36.59670  ? 446 ASN A O   1 
ATOM   3406 C CB  . ASN A 1 447 ? -32.65098 -17.07760 14.27992  1.000 42.50300  ? 446 ASN A CB  1 
ATOM   3407 C CG  . ASN A 1 447 ? -31.90588 -15.96135 13.56746  1.000 46.04045  ? 446 ASN A CG  1 
ATOM   3408 O OD1 . ASN A 1 447 ? -30.74902 -16.12984 13.15477  1.000 48.95194  ? 446 ASN A OD1 1 
ATOM   3409 N ND2 . ASN A 1 447 ? -32.56233 -14.81529 13.41867  1.000 41.62031  ? 446 ASN A ND2 1 
ATOM   3410 N N   . LEU A 1 448 ? -33.33309 -20.56008 14.39043  1.000 37.17813  ? 447 LEU A N   1 
ATOM   3411 C CA  . LEU A 1 448 ? -33.73938 -21.68772 15.21512  1.000 34.68121  ? 447 LEU A CA  1 
ATOM   3412 C C   . LEU A 1 448 ? -33.01012 -22.94143 14.76016  1.000 40.83874  ? 447 LEU A C   1 
ATOM   3413 O O   . LEU A 1 448 ? -32.89170 -23.19453 13.55751  1.000 46.89277  ? 447 LEU A O   1 
ATOM   3414 C CB  . LEU A 1 448 ? -35.24186 -21.94107 15.13482  1.000 37.12703  ? 447 LEU A CB  1 
ATOM   3415 C CG  . LEU A 1 448 ? -36.16372 -21.15655 16.06616  1.000 40.60269  ? 447 LEU A CG  1 
ATOM   3416 C CD1 . LEU A 1 448 ? -35.73543 -21.40550 17.49725  1.000 39.17698  ? 447 LEU A CD1 1 
ATOM   3417 C CD2 . LEU A 1 448 ? -36.19687 -19.67162 15.73653  1.000 39.78205  ? 447 LEU A CD2 1 
ATOM   3418 N N   . ILE A 1 449 ? -32.52219 -23.72336 15.71864  1.000 35.58093  ? 448 ILE A N   1 
ATOM   3419 C CA  . ILE A 1 449 ? -31.95729 -25.03784 15.45475  1.000 30.51951  ? 448 ILE A CA  1 
ATOM   3420 C C   . ILE A 1 449 ? -32.82654 -26.04461 16.19573  1.000 37.41326  ? 448 ILE A C   1 
ATOM   3421 O O   . ILE A 1 449 ? -33.00366 -25.94150 17.42013  1.000 32.48604  ? 448 ILE A O   1 
ATOM   3422 C CB  . ILE A 1 449 ? -30.49528 -25.13231 15.90765  1.000 31.28195  ? 448 ILE A CB  1 
ATOM   3423 C CG1 . ILE A 1 449 ? -29.66826 -24.00782 15.27283  1.000 31.00646  ? 448 ILE A CG1 1 
ATOM   3424 C CG2 . ILE A 1 449 ? -29.94004 -26.48993 15.58423  1.000 32.59917  ? 448 ILE A CG2 1 
ATOM   3425 C CD1 . ILE A 1 449 ? -28.31162 -23.70794 15.94019  1.000 22.99374  ? 448 ILE A CD1 1 
ATOM   3426 N N   . LEU A 1 450 ? -33.39639 -26.99203 15.45687  1.000 33.61396  ? 449 LEU A N   1 
ATOM   3427 C CA  . LEU A 1 450 ? -34.19371 -28.03291 16.07878  1.000 29.68932  ? 449 LEU A CA  1 
ATOM   3428 C C   . LEU A 1 450 ? -33.30326 -29.15146 16.58317  1.000 35.03845  ? 449 LEU A C   1 
ATOM   3429 O O   . LEU A 1 450 ? -32.31041 -29.50926 15.94416  1.000 35.07903  ? 449 LEU A O   1 
ATOM   3430 C CB  . LEU A 1 450 ? -35.19285 -28.60209 15.09166  1.000 29.40222  ? 449 LEU A CB  1 
ATOM   3431 C CG  . LEU A 1 450 ? -36.17406 -27.59105 14.53735  1.000 37.57462  ? 449 LEU A CG  1 
ATOM   3432 C CD1 . LEU A 1 450 ? -37.40379 -28.34616 14.07603  1.000 36.16944  ? 449 LEU A CD1 1 
ATOM   3433 C CD2 . LEU A 1 450 ? -36.53704 -26.56472 15.59891  1.000 35.64140  ? 449 LEU A CD2 1 
ATOM   3434 N N   . VAL A 1 451 ? -33.65092 -29.68994 17.74358  1.000 29.80322  ? 450 VAL A N   1 
ATOM   3435 C CA  . VAL A 1 451 ? -33.05309 -30.91552 18.24237  1.000 32.35572  ? 450 VAL A CA  1 
ATOM   3436 C C   . VAL A 1 451 ? -34.04451 -32.03299 17.98921  1.000 39.60290  ? 450 VAL A C   1 
ATOM   3437 O O   . VAL A 1 451 ? -35.17218 -32.00182 18.50072  1.000 37.77534  ? 450 VAL A O   1 
ATOM   3438 C CB  . VAL A 1 451 ? -32.71349 -30.82240 19.73158  1.000 39.12137  ? 450 VAL A CB  1 
ATOM   3439 C CG1 . VAL A 1 451 ? -31.84473 -32.02116 20.15344  1.000 37.85554  ? 450 VAL A CG1 1 
ATOM   3440 C CG2 . VAL A 1 451 ? -32.04154 -29.49774 20.02657  1.000 40.07373  ? 450 VAL A CG2 1 
ATOM   3441 N N   . LEU A 1 452 ? -33.63534 -33.01039 17.18931  1.000 38.92478  ? 451 LEU A N   1 
ATOM   3442 C CA  . LEU A 1 452 ? -34.48670 -34.13424 16.84274  1.000 38.90613  ? 451 LEU A CA  1 
ATOM   3443 C C   . LEU A 1 452 ? -33.97304 -35.39396 17.52824  1.000 39.31161  ? 451 LEU A C   1 
ATOM   3444 O O   . LEU A 1 452 ? -32.78156 -35.51969 17.83036  1.000 41.75509  ? 451 LEU A O   1 
ATOM   3445 C CB  . LEU A 1 452 ? -34.55288 -34.33543 15.31897  1.000 42.05690  ? 451 LEU A CB  1 
ATOM   3446 C CG  . LEU A 1 452 ? -35.12797 -33.19813 14.45186  1.000 40.51581  ? 451 LEU A CG  1 
ATOM   3447 C CD1 . LEU A 1 452 ? -35.27027 -33.65015 13.01991  1.000 33.93489  ? 451 LEU A CD1 1 
ATOM   3448 C CD2 . LEU A 1 452 ? -36.46665 -32.68851 14.96869  1.000 33.93179  ? 451 LEU A CD2 1 
ATOM   3449 N N   . ASP A 1 453 ? -34.89003 -36.31233 17.80865  1.000 36.13923  ? 452 ASP A N   1 
ATOM   3450 C CA  . ASP A 1 453 ? -34.53744 -37.65307 18.25028  1.000 35.11633  ? 452 ASP A CA  1 
ATOM   3451 C C   . ASP A 1 453 ? -35.16492 -38.61514 17.26063  1.000 38.88389  ? 452 ASP A C   1 
ATOM   3452 O O   . ASP A 1 453 ? -36.39192 -38.74367 17.21905  1.000 39.84824  ? 452 ASP A O   1 
ATOM   3453 C CB  . ASP A 1 453 ? -35.01904 -37.92230 19.66973  1.000 35.10169  ? 452 ASP A CB  1 
ATOM   3454 C CG  . ASP A 1 453 ? -34.63727 -39.30666 20.16596  1.000 41.17303  ? 452 ASP A CG  1 
ATOM   3455 O OD1 . ASP A 1 453 ? -34.54287 -40.26381 19.36226  1.000 43.71371  ? 452 ASP A OD1 1 
ATOM   3456 O OD2 . ASP A 1 453 ? -34.41789 -39.43840 21.38040  1.000 49.61629  ? 452 ASP A OD2 1 
ATOM   3457 N N   . GLY A 1 454 ? -34.32703 -39.28186 16.46655  1.000 37.09951  ? 453 GLY A N   1 
ATOM   3458 C CA  . GLY A 1 454 ? -34.81985 -40.21727 15.47792  1.000 33.85019  ? 453 GLY A CA  1 
ATOM   3459 C C   . GLY A 1 454 ? -35.89614 -39.60311 14.62365  1.000 32.58928  ? 453 GLY A C   1 
ATOM   3460 O O   . GLY A 1 454 ? -36.81218 -40.29157 14.18253  1.000 35.37405  ? 453 GLY A O   1 
ATOM   3461 N N   . GLY A 1 455 ? -35.80943 -38.29640 14.41403  1.000 34.24834  ? 454 GLY A N   1 
ATOM   3462 C CA  . GLY A 1 455 ? -36.76005 -37.57489 13.61160  1.000 37.84570  ? 454 GLY A CA  1 
ATOM   3463 C C   . GLY A 1 455 ? -37.87526 -36.90024 14.38487  1.000 36.47392  ? 454 GLY A C   1 
ATOM   3464 O O   . GLY A 1 455 ? -38.54214 -36.01612 13.83207  1.000 40.70946  ? 454 GLY A O   1 
ATOM   3465 N N   . ALA A 1 456 ? -38.10559 -37.28703 15.63217  1.000 38.71787  ? 455 ALA A N   1 
ATOM   3466 C CA  . ALA A 1 456 ? -39.18097 -36.64009 16.38403  1.000 38.96821  ? 455 ALA A CA  1 
ATOM   3467 C C   . ALA A 1 456 ? -38.69594 -35.31872 16.97792  1.000 36.50927  ? 455 ALA A C   1 
ATOM   3468 O O   . ALA A 1 456 ? -37.53849 -35.21998 17.39445  1.000 37.88751  ? 455 ALA A O   1 
ATOM   3469 C CB  . ALA A 1 456 ? -39.68463 -37.54942 17.49915  1.000 34.26476  ? 455 ALA A CB  1 
ATOM   3470 N N   . PRO A 1 457 ? -39.55180 -34.29158 17.02383  1.000 34.96755  ? 456 PRO A N   1 
ATOM   3471 C CA  . PRO A 1 457 ? -39.14402 -33.02396 17.64910  1.000 35.72055  ? 456 PRO A CA  1 
ATOM   3472 C C   . PRO A 1 457 ? -38.90821 -33.22764 19.13694  1.000 37.42312  ? 456 PRO A C   1 
ATOM   3473 O O   . PRO A 1 457 ? -39.58477 -34.03395 19.78066  1.000 43.37404  ? 456 PRO A O   1 
ATOM   3474 C CB  . PRO A 1 457 ? -40.33198 -32.08829 17.39424  1.000 31.08759  ? 456 PRO A CB  1 
ATOM   3475 C CG  . PRO A 1 457 ? -41.22548 -32.80977 16.43223  1.000 36.46786  ? 456 PRO A CG  1 
ATOM   3476 C CD  . PRO A 1 457 ? -40.95761 -34.27002 16.59499  1.000 35.86186  ? 456 PRO A CD  1 
ATOM   3477 N N   . VAL A 1 458 ? -37.91428 -32.51376 19.67193  1.000 35.90159  ? 457 VAL A N   1 
ATOM   3478 C CA  . VAL A 1 458 ? -37.54897 -32.61010 21.08335  1.000 36.87582  ? 457 VAL A CA  1 
ATOM   3479 C C   . VAL A 1 458 ? -37.54489 -31.22350 21.72055  1.000 36.18583  ? 457 VAL A C   1 
ATOM   3480 O O   . VAL A 1 458 ? -38.26269 -30.98087 22.69820  1.000 35.83181  ? 457 VAL A O   1 
ATOM   3481 C CB  . VAL A 1 458 ? -36.18377 -33.30133 21.26631  1.000 37.26409  ? 457 VAL A CB  1 
ATOM   3482 C CG1 . VAL A 1 458 ? -35.77855 -33.24916 22.70885  1.000 32.08406  ? 457 VAL A CG1 1 
ATOM   3483 C CG2 . VAL A 1 458 ? -36.23511 -34.74034 20.77998  1.000 31.07053  ? 457 VAL A CG2 1 
ATOM   3484 N N   . ARG A 1 459 ? -36.74998 -30.30628 21.17132  1.000 35.59910  ? 458 ARG A N   1 
ATOM   3485 C CA  . ARG A 1 459 ? -36.62287 -28.94854 21.70223  1.000 35.24351  ? 458 ARG A CA  1 
ATOM   3486 C C   . ARG A 1 459 ? -35.91802 -28.07910 20.66524  1.000 34.54294  ? 458 ARG A C   1 
ATOM   3487 O O   . ARG A 1 459 ? -35.62275 -28.52685 19.55259  1.000 36.47929  ? 458 ARG A O   1 
ATOM   3488 C CB  . ARG A 1 459 ? -35.85818 -28.96234 23.01001  1.000 34.38742  ? 458 ARG A CB  1 
ATOM   3489 C CG  . ARG A 1 459 ? -34.50125 -29.48093 22.77208  1.000 32.01142  ? 458 ARG A CG  1 
ATOM   3490 C CD  . ARG A 1 459 ? -33.73108 -29.35465 23.99891  1.000 33.03650  ? 458 ARG A CD  1 
ATOM   3491 N NE  . ARG A 1 459 ? -32.81445 -30.46505 24.12905  1.000 35.51892  ? 458 ARG A NE  1 
ATOM   3492 C CZ  . ARG A 1 459 ? -31.50865 -30.29675 24.23093  1.000 44.47446  ? 458 ARG A CZ  1 
ATOM   3493 N NH1 . ARG A 1 459 ? -30.97005 -29.08688 24.17731  1.000 32.46584  ? 458 ARG A NH1 1 
ATOM   3494 N NH2 . ARG A 1 459 ? -30.72852 -31.36372 24.39533  1.000 53.50681  ? 458 ARG A NH2 1 
ATOM   3495 N N   . ALA A 1 460 ? -35.62295 -26.83532 21.03481  1.000 33.92283  ? 459 ALA A N   1 
ATOM   3496 C CA  . ALA A 1 460 ? -35.16029 -25.85969 20.06216  1.000 28.17863  ? 459 ALA A CA  1 
ATOM   3497 C C   . ALA A 1 460 ? -34.16804 -24.91919 20.71959  1.000 32.95264  ? 459 ALA A C   1 
ATOM   3498 O O   . ALA A 1 460 ? -34.22792 -24.67180 21.92508  1.000 37.22214  ? 459 ALA A O   1 
ATOM   3499 C CB  . ALA A 1 460 ? -36.32844 -25.05705 19.47835  1.000 28.73352  ? 459 ALA A CB  1 
ATOM   3500 N N   . VAL A 1 461 ? -33.26506 -24.38493 19.90536  1.000 36.95021  ? 460 VAL A N   1 
ATOM   3501 C CA  . VAL A 1 461 ? -32.24169 -23.43779 20.33145  1.000 34.94645  ? 460 VAL A CA  1 
ATOM   3502 C C   . VAL A 1 461 ? -32.40866 -22.16691 19.51266  1.000 36.18048  ? 460 VAL A C   1 
ATOM   3503 O O   . VAL A 1 461 ? -32.50285 -22.23788 18.28205  1.000 41.95107  ? 460 VAL A O   1 
ATOM   3504 C CB  . VAL A 1 461 ? -30.83229 -24.01869 20.11743  1.000 36.59350  ? 460 VAL A CB  1 
ATOM   3505 C CG1 . VAL A 1 461 ? -29.80645 -23.18401 20.84719  1.000 37.22239  ? 460 VAL A CG1 1 
ATOM   3506 C CG2 . VAL A 1 461 ? -30.77308 -25.49787 20.50721  1.000 22.58675  ? 460 VAL A CG2 1 
ATOM   3507 N N   . LEU A 1 462 ? -32.42600 -21.01314 20.18113  1.000 34.75831  ? 461 LEU A N   1 
ATOM   3508 C CA  . LEU A 1 462 ? -32.50132 -19.70094 19.53071  1.000 34.64540  ? 461 LEU A CA  1 
ATOM   3509 C C   . LEU A 1 462 ? -31.10961 -19.07527 19.43522  1.000 38.81248  ? 461 LEU A C   1 
ATOM   3510 O O   . LEU A 1 462 ? -30.32978 -19.15483 20.38994  1.000 40.01428  ? 461 LEU A O   1 
ATOM   3511 C CB  . LEU A 1 462 ? -33.42190 -18.77502 20.32181  1.000 31.08748  ? 461 LEU A CB  1 
ATOM   3512 C CG  . LEU A 1 462 ? -33.84777 -17.50878 19.60349  1.000 36.66502  ? 461 LEU A CG  1 
ATOM   3513 C CD1 . LEU A 1 462 ? -34.58518 -17.85877 18.30045  1.000 36.92569  ? 461 LEU A CD1 1 
ATOM   3514 C CD2 . LEU A 1 462 ? -34.70176 -16.62849 20.50949  1.000 36.94139  ? 461 LEU A CD2 1 
ATOM   3515 N N   . LYS A 1 463 ? -30.78433 -18.42990 18.29927  1.000 38.77297  ? 462 LYS A N   1 
ATOM   3516 C CA  . LYS A 1 463 ? -29.37092 -18.07522 18.17637  1.000 38.36442  ? 462 LYS A CA  1 
ATOM   3517 C C   . LYS A 1 463 ? -29.06575 -16.59009 18.00963  1.000 43.74605  ? 462 LYS A C   1 
ATOM   3518 O O   . LYS A 1 463 ? -28.06735 -16.12557 18.57756  1.000 53.19684  ? 462 LYS A O   1 
ATOM   3519 C CB  . LYS A 1 463 ? -28.69263 -18.87285 17.04260  1.000 39.48737  ? 462 LYS A CB  1 
ATOM   3520 C CG  . LYS A 1 463 ? -28.82730 -18.28288 15.64946  1.000 49.94261  ? 462 LYS A CG  1 
ATOM   3521 C CD  . LYS A 1 463 ? -28.51256 -19.29245 14.53596  1.000 51.01733  ? 462 LYS A CD  1 
ATOM   3522 C CE  . LYS A 1 463 ? -27.07283 -19.10967 14.01767  1.000 63.53157  ? 462 LYS A CE  1 
ATOM   3523 N NZ  . LYS A 1 463 ? -26.52103 -20.26629 13.23451  1.000 56.56448  ? 462 LYS A NZ  1 
ATOM   3524 N N   . ASP A 1 464 ? -29.84518 -15.80065 17.27656  1.000 37.07296  ? 463 ASP A N   1 
ATOM   3525 C CA  . ASP A 1 464 ? -29.38808 -14.43114 16.94536  1.000 52.48535  ? 463 ASP A CA  1 
ATOM   3526 C C   . ASP A 1 464 ? -29.97109 -13.42899 17.95457  1.000 52.13734  ? 463 ASP A C   1 
ATOM   3527 O O   . ASP A 1 464 ? -31.14890 -13.06712 17.87141  1.000 56.70477  ? 463 ASP A O   1 
ATOM   3528 C CB  . ASP A 1 464 ? -29.75414 -14.06469 15.50184  1.000 56.99524  ? 463 ASP A CB  1 
ATOM   3529 C CG  . ASP A 1 464 ? -28.89633 -12.91858 14.94166  1.000 62.91175  ? 463 ASP A CG  1 
ATOM   3530 O OD1 . ASP A 1 464 ? -27.93115 -12.51235 15.63510  1.000 68.27428  ? 463 ASP A OD1 1 
ATOM   3531 O OD2 . ASP A 1 464 ? -29.19745 -12.40747 13.82960  1.000 56.98303  ? 463 ASP A OD2 1 
ATOM   3532 N N   . ILE A 1 465 ? -29.14398 -12.94805 18.89326  1.000 46.79804  ? 464 ILE A N   1 
ATOM   3533 C CA  . ILE A 1 465 ? -29.69232 -12.40235 20.14025  1.000 42.47845  ? 464 ILE A CA  1 
ATOM   3534 C C   . ILE A 1 465 ? -29.44330 -10.91431 20.36235  1.000 46.40840  ? 464 ILE A C   1 
ATOM   3535 O O   . ILE A 1 465 ? -30.39646 -10.14629 20.53071  1.000 48.66869  ? 464 ILE A O   1 
ATOM   3536 C CB  . ILE A 1 465 ? -29.17202 -13.20828 21.34019  1.000 45.77076  ? 464 ILE A CB  1 
ATOM   3537 C CG1 . ILE A 1 465 ? -29.53893 -14.68025 21.13800  1.000 43.28840  ? 464 ILE A CG1 1 
ATOM   3538 C CG2 . ILE A 1 465 ? -29.72055 -12.64252 22.65120  1.000 45.66970  ? 464 ILE A CG2 1 
ATOM   3539 C CD1 . ILE A 1 465 ? -29.62761 -15.48657 22.37860  1.000 42.78786  ? 464 ILE A CD1 1 
ATOM   3540 N N   . GLY A 1 466 ? -28.17776 -10.49158 20.39209  1.000 42.00860  ? 465 GLY A N   1 
ATOM   3541 C CA  . GLY A 1 466 ? -27.88331 -9.09957  20.71899  1.000 42.65936  ? 465 GLY A CA  1 
ATOM   3542 C C   . GLY A 1 466 ? -28.32292 -8.09769  19.66100  1.000 47.64062  ? 465 GLY A C   1 
ATOM   3543 O O   . GLY A 1 466 ? -28.76148 -6.99285  19.98683  1.000 50.76522  ? 465 GLY A O   1 
ATOM   3544 N N   . GLU A 1 467 ? -28.19402 -8.45214  18.38187  1.000 54.52668  ? 466 GLU A N   1 
ATOM   3545 C CA  . GLU A 1 467 ? -28.50407 -7.50102  17.32179  1.000 51.18066  ? 466 GLU A CA  1 
ATOM   3546 C C   . GLU A 1 467 ? -29.98783 -7.45513  16.98128  1.000 54.42996  ? 466 GLU A C   1 
ATOM   3547 O O   . GLU A 1 467 ? -30.43285 -6.48681  16.35063  1.000 54.16254  ? 466 GLU A O   1 
ATOM   3548 C CB  . GLU A 1 467 ? -27.70359 -7.83122  16.05853  1.000 51.03176  ? 466 GLU A CB  1 
ATOM   3549 N N   . GLU A 1 468 ? -30.76759 -8.46331  17.38550  1.000 51.71514  ? 467 GLU A N   1 
ATOM   3550 C CA  . GLU A 1 468 ? -32.15389 -8.57356  16.94182  1.000 53.10108  ? 467 GLU A CA  1 
ATOM   3551 C C   . GLU A 1 468 ? -33.19947 -8.36965  18.03589  1.000 49.75292  ? 467 GLU A C   1 
ATOM   3552 O O   . GLU A 1 468 ? -34.38996 -8.30436  17.70357  1.000 51.12291  ? 467 GLU A O   1 
ATOM   3553 C CB  . GLU A 1 468 ? -32.40603 -9.94648  16.28154  1.000 53.75893  ? 467 GLU A CB  1 
ATOM   3554 C CG  . GLU A 1 468 ? -31.25385 -10.50582 15.46644  1.000 50.14999  ? 467 GLU A CG  1 
ATOM   3555 C CD  . GLU A 1 468 ? -31.14795 -9.87250  14.09924  1.000 57.96503  ? 467 GLU A CD  1 
ATOM   3556 O OE1 . GLU A 1 468 ? -32.19622 -9.39679  13.59858  1.000 52.73784  ? 467 GLU A OE1 1 
ATOM   3557 O OE2 . GLU A 1 468 ? -30.02175 -9.85098  13.52959  1.000 67.39908  ? 467 GLU A OE2 1 
ATOM   3558 N N   . ILE A 1 469 ? -32.80324 -8.26073  19.32606  1.000 52.36972  ? 468 ILE A N   1 
ATOM   3559 C CA  . ILE A 1 469 ? -33.76458 -8.31029  20.42847  1.000 44.43200  ? 468 ILE A CA  1 
ATOM   3560 C C   . ILE A 1 469 ? -34.44730 -6.96263  20.59928  1.000 47.57833  ? 468 ILE A C   1 
ATOM   3561 O O   . ILE A 1 469 ? -33.82029 -5.90645  20.47960  1.000 47.73521  ? 468 ILE A O   1 
ATOM   3562 C CB  . ILE A 1 469 ? -33.09350 -8.73945  21.74055  1.000 43.23838  ? 468 ILE A CB  1 
ATOM   3563 C CG1 . ILE A 1 469 ? -34.09097 -8.58842  22.88690  1.000 53.96786  ? 468 ILE A CG1 1 
ATOM   3564 C CG2 . ILE A 1 469 ? -31.93571 -7.85424  22.04738  1.000 48.13521  ? 468 ILE A CG2 1 
ATOM   3565 C CD1 . ILE A 1 469 ? -33.53253 -8.87175  24.26153  1.000 54.35579  ? 468 ILE A CD1 1 
ATOM   3566 N N   . CYS A 1 470 ? -35.75082 -7.00766  20.86720  1.000 52.37840  ? 469 CYS A N   1 
ATOM   3567 C CA  . CYS A 1 470 ? -36.55708 -5.85601  21.25095  1.000 48.10985  ? 469 CYS A CA  1 
ATOM   3568 C C   . CYS A 1 470 ? -37.02465 -6.07423  22.67976  1.000 47.91265  ? 469 CYS A C   1 
ATOM   3569 O O   . CYS A 1 470 ? -37.68691 -7.08010  22.96509  1.000 49.66665  ? 469 CYS A O   1 
ATOM   3570 C CB  . CYS A 1 470 ? -37.76943 -5.70115  20.33429  1.000 47.97776  ? 469 CYS A CB  1 
ATOM   3571 S SG  . CYS A 1 470 ? -37.42659 -5.02712  18.71155  1.000 64.46211  ? 469 CYS A SG  1 
ATOM   3572 N N   . ILE A 1 471 ? -36.68721 -5.14747  23.57363  1.000 50.55126  ? 470 ILE A N   1 
ATOM   3573 C CA  . ILE A 1 471 ? -37.17851 -5.18575  24.95092  1.000 52.74119  ? 470 ILE A CA  1 
ATOM   3574 C C   . ILE A 1 471 ? -38.29934 -4.16362  25.08313  1.000 46.35955  ? 470 ILE A C   1 
ATOM   3575 O O   . ILE A 1 471 ? -38.08414 -2.96101  24.89054  1.000 43.44280  ? 470 ILE A O   1 
ATOM   3576 C CB  . ILE A 1 471 ? -36.06070 -4.93479  25.98022  1.000 44.40477  ? 470 ILE A CB  1 
ATOM   3577 C CG1 . ILE A 1 471 ? -34.82457 -5.75613  25.65019  1.000 42.23861  ? 470 ILE A CG1 1 
ATOM   3578 C CG2 . ILE A 1 471 ? -36.52522 -5.32851  27.37340  1.000 47.83588  ? 470 ILE A CG2 1 
ATOM   3579 C CD1 . ILE A 1 471 ? -33.57246 -5.18910  26.23867  1.000 44.98081  ? 470 ILE A CD1 1 
ATOM   3580 N N   . PHE A 1 472 ? -39.49634 -4.64443  25.41224  1.000 46.76654  ? 471 PHE A N   1 
ATOM   3581 C CA  . PHE A 1 472 ? -40.65243 -3.77751  25.55507  1.000 52.41028  ? 471 PHE A CA  1 
ATOM   3582 C C   . PHE A 1 472 ? -40.85474 -3.24212  26.97145  1.000 57.64378  ? 471 PHE A C   1 
ATOM   3583 O O   . PHE A 1 472 ? -41.62220 -2.29133  27.14797  1.000 65.92064  ? 471 PHE A O   1 
ATOM   3584 C CB  . PHE A 1 472 ? -41.91477 -4.51221  25.11269  1.000 52.17021  ? 471 PHE A CB  1 
ATOM   3585 C CG  . PHE A 1 472 ? -41.92891 -4.86290  23.66190  1.000 51.79635  ? 471 PHE A CG  1 
ATOM   3586 C CD1 . PHE A 1 472 ? -42.35870 -3.95237  22.72550  1.000 51.66691  ? 471 PHE A CD1 1 
ATOM   3587 C CD2 . PHE A 1 472 ? -41.52126 -6.11746  23.23499  1.000 50.81436  ? 471 PHE A CD2 1 
ATOM   3588 C CE1 . PHE A 1 472 ? -42.37994 -4.28388  21.38370  1.000 54.59881  ? 471 PHE A CE1 1 
ATOM   3589 C CE2 . PHE A 1 472 ? -41.53761 -6.45325  21.90103  1.000 50.13688  ? 471 PHE A CE2 1 
ATOM   3590 C CZ  . PHE A 1 472 ? -41.96225 -5.53039  20.96942  1.000 50.62848  ? 471 PHE A CZ  1 
ATOM   3591 N N   . ASP A 1 473 ? -40.20557 -3.80567  27.99318  1.000 57.21293  ? 472 ASP A N   1 
ATOM   3592 C CA  . ASP A 1 473 ? -40.44921 -3.23124  29.32157  1.000 70.41076  ? 472 ASP A CA  1 
ATOM   3593 C C   . ASP A 1 473 ? -39.22737 -3.47566  30.20991  1.000 74.28908  ? 472 ASP A C   1 
ATOM   3594 O O   . ASP A 1 473 ? -39.22061 -4.35421  31.08263  1.000 73.24267  ? 472 ASP A O   1 
ATOM   3595 C CB  . ASP A 1 473 ? -41.71707 -3.78892  29.96810  1.000 71.94087  ? 472 ASP A CB  1 
ATOM   3596 C CG  . ASP A 1 473 ? -42.27474 -2.86241  31.03396  1.000 77.25210  ? 472 ASP A CG  1 
ATOM   3597 O OD1 . ASP A 1 473 ? -42.53968 -1.66888  30.72662  1.000 69.82859  ? 472 ASP A OD1 1 
ATOM   3598 O OD2 . ASP A 1 473 ? -42.42146 -3.33219  32.18338  1.000 78.53053  ? 472 ASP A OD2 1 
ATOM   3599 N N   . ALA A 1 474 ? -38.19370 -2.64665  30.00626  1.000 66.65908  ? 473 ALA A N   1 
ATOM   3600 C CA  . ALA A 1 474 ? -36.98393 -2.80227  30.79639  1.000 72.37856  ? 473 ALA A CA  1 
ATOM   3601 C C   . ALA A 1 474 ? -37.16464 -2.19892  32.18829  1.000 79.28235  ? 473 ALA A C   1 
ATOM   3602 O O   . ALA A 1 474 ? -37.86162 -1.19024  32.35008  1.000 85.67063  ? 473 ALA A O   1 
ATOM   3603 C CB  . ALA A 1 474 ? -35.80356 -2.13810  30.10129  1.000 73.82737  ? 473 ALA A CB  1 
ATOM   3604 N N   . PRO A 1 475 ? -36.54322 -2.80312  33.21923  1.000 74.29730  ? 474 PRO A N   1 
ATOM   3605 C CA  . PRO A 1 475 ? -36.58715 -2.19813  34.56038  1.000 76.18376  ? 474 PRO A CA  1 
ATOM   3606 C C   . PRO A 1 475 ? -35.87091 -0.85390  34.60384  1.000 73.69875  ? 474 PRO A C   1 
ATOM   3607 O O   . PRO A 1 475 ? -35.41504 -0.35161  33.57275  1.000 72.89405  ? 474 PRO A O   1 
ATOM   3608 C CB  . PRO A 1 475 ? -35.89028 -3.24222  35.45143  1.000 71.04528  ? 474 PRO A CB  1 
ATOM   3609 C CG  . PRO A 1 475 ? -35.90493 -4.51159  34.65806  1.000 70.71110  ? 474 PRO A CG  1 
ATOM   3610 C CD  . PRO A 1 475 ? -35.83413 -4.09343  33.21744  1.000 70.03808  ? 474 PRO A CD  1 
ATOM   3611 N N   . ASP A 1 476 ? -35.76857 -0.25685  35.79260  1.000 75.25921  ? 475 ASP A N   1 
ATOM   3612 C CA  . ASP A 1 476 ? -35.09552 1.02927   35.91377  1.000 69.32816  ? 475 ASP A CA  1 
ATOM   3613 C C   . ASP A 1 476 ? -33.58067 0.90218   35.79463  1.000 71.53968  ? 475 ASP A C   1 
ATOM   3614 O O   . ASP A 1 476 ? -32.91036 1.89056   35.46945  1.000 74.78432  ? 475 ASP A O   1 
ATOM   3615 C CB  . ASP A 1 476 ? -35.45924 1.69562   37.24309  1.000 69.99486  ? 475 ASP A CB  1 
ATOM   3616 C CG  . ASP A 1 476 ? -36.87648 2.24833   37.25721  1.000 80.18131  ? 475 ASP A CG  1 
ATOM   3617 O OD1 . ASP A 1 476 ? -37.82170 1.44102   37.39953  1.000 85.87031  ? 475 ASP A OD1 1 
ATOM   3618 O OD2 . ASP A 1 476 ? -37.04707 3.48553   37.12877  1.000 79.02323  ? 475 ASP A OD2 1 
ATOM   3619 N N   . ASP A 1 477 ? -33.02245 -0.28450  36.03705  1.000 70.06738  ? 476 ASP A N   1 
ATOM   3620 C CA  . ASP A 1 477 ? -31.58480 -0.49642  35.91729  1.000 72.00973  ? 476 ASP A CA  1 
ATOM   3621 C C   . ASP A 1 477 ? -31.21166 -1.28496  34.66355  1.000 69.89112  ? 476 ASP A C   1 
ATOM   3622 O O   . ASP A 1 477 ? -30.20226 -1.99276  34.65643  1.000 68.91512  ? 476 ASP A O   1 
ATOM   3623 C CB  . ASP A 1 477 ? -31.04094 -1.20635  37.15030  1.000 64.61815  ? 476 ASP A CB  1 
ATOM   3624 C CG  . ASP A 1 477 ? -31.83467 -2.43498  37.49358  1.000 69.72956  ? 476 ASP A CG  1 
ATOM   3625 O OD1 . ASP A 1 477 ? -32.91398 -2.61982  36.87249  1.000 67.33384  ? 476 ASP A OD1 1 
ATOM   3626 O OD2 . ASP A 1 477 ? -31.37754 -3.20634  38.37482  1.000 66.25591  ? 476 ASP A OD2 1 
ATOM   3627 N N   . ILE A 1 478 ? -32.02372 -1.20246  33.61403  1.000 63.98080  ? 477 ILE A N   1 
ATOM   3628 C CA  . ILE A 1 478 ? -31.58803 -1.66534  32.30375  1.000 64.54345  ? 477 ILE A CA  1 
ATOM   3629 C C   . ILE A 1 478 ? -30.22030 -1.03447  32.09942  1.000 62.61342  ? 477 ILE A C   1 
ATOM   3630 O O   . ILE A 1 478 ? -30.10359 0.18970   32.21545  1.000 65.47657  ? 477 ILE A O   1 
ATOM   3631 C CB  . ILE A 1 478 ? -32.56897 -1.26068  31.19260  1.000 59.04367  ? 477 ILE A CB  1 
ATOM   3632 N N   . PRO A 1 479 ? -29.15761 -1.80649  31.88231  1.000 62.67659  ? 478 PRO A N   1 
ATOM   3633 C CA  . PRO A 1 479 ? -27.87304 -1.18217  31.55922  1.000 58.64229  ? 478 PRO A CA  1 
ATOM   3634 C C   . PRO A 1 479 ? -28.03708 -0.31759  30.32321  1.000 55.15816  ? 478 PRO A C   1 
ATOM   3635 O O   . PRO A 1 479 ? -28.79002 -0.66184  29.41322  1.000 61.64501  ? 478 PRO A O   1 
ATOM   3636 C CB  . PRO A 1 479 ? -26.94006 -2.37355  31.30607  1.000 58.73903  ? 478 PRO A CB  1 
ATOM   3637 C CG  . PRO A 1 479 ? -27.61464 -3.55144  31.88947  1.000 52.02482  ? 478 PRO A CG  1 
ATOM   3638 C CD  . PRO A 1 479 ? -29.08777 -3.27672  31.84948  1.000 60.17480  ? 478 PRO A CD  1 
ATOM   3639 N N   . GLU A 1 480 ? -27.35779 0.83494   30.31445  1.000 56.50281  ? 479 GLU A N   1 
ATOM   3640 C CA  . GLU A 1 480 ? -27.45370 1.73855   29.17070  1.000 58.05935  ? 479 GLU A CA  1 
ATOM   3641 C C   . GLU A 1 480 ? -27.00394 1.05222   27.89162  1.000 63.64215  ? 479 GLU A C   1 
ATOM   3642 O O   . GLU A 1 480 ? -27.47203 1.40093   26.80001  1.000 66.39690  ? 479 GLU A O   1 
ATOM   3643 C CB  . GLU A 1 480 ? -26.62242 2.99709   29.40887  1.000 56.73274  ? 479 GLU A CB  1 
ATOM   3644 N N   . SER A 1 481 ? -26.11255 0.06134   28.01542  1.000 63.05758  ? 480 SER A N   1 
ATOM   3645 C CA  . SER A 1 481 ? -25.68122 -0.73981  26.87387  1.000 59.64545  ? 480 SER A CA  1 
ATOM   3646 C C   . SER A 1 481 ? -26.85466 -1.33458  26.11138  1.000 62.37245  ? 480 SER A C   1 
ATOM   3647 O O   . SER A 1 481 ? -26.73111 -1.62963  24.91669  1.000 68.51488  ? 480 SER A O   1 
ATOM   3648 C CB  . SER A 1 481 ? -24.75716 -1.86496  27.34440  1.000 60.11670  ? 480 SER A CB  1 
ATOM   3649 O OG  . SER A 1 481 ? -25.13072 -2.32800  28.63852  1.000 65.18995  ? 480 SER A OG  1 
ATOM   3650 N N   . CYS A 1 482 ? -27.98980 -1.53678  26.77509  1.000 54.46848  ? 481 CYS A N   1 
ATOM   3651 C CA  . CYS A 1 482 ? -29.15046 -2.11166  26.12202  1.000 54.13037  ? 481 CYS A CA  1 
ATOM   3652 C C   . CYS A 1 482 ? -30.17301 -1.06339  25.74450  1.000 58.15226  ? 481 CYS A C   1 
ATOM   3653 O O   . CYS A 1 482 ? -31.29342 -1.41959  25.36537  1.000 59.11214  ? 481 CYS A O   1 
ATOM   3654 C CB  . CYS A 1 482 ? -29.77951 -3.17869  27.01033  1.000 46.52526  ? 481 CYS A CB  1 
ATOM   3655 S SG  . CYS A 1 482 ? -28.52632 -4.12271  27.89438  1.000 56.60295  ? 481 CYS A SG  1 
ATOM   3656 N N   . ARG A 1 483 ? -29.81309 0.22122   25.83051  1.000 58.61235  ? 482 ARG A N   1 
ATOM   3657 C CA  . ARG A 1 483 ? -30.73554 1.26576   25.39773  1.000 58.43270  ? 482 ARG A CA  1 
ATOM   3658 C C   . ARG A 1 483 ? -31.02144 1.15710   23.90679  1.000 57.30214  ? 482 ARG A C   1 
ATOM   3659 O O   . ARG A 1 483 ? -32.11547 1.51750   23.45384  1.000 60.03246  ? 482 ARG A O   1 
ATOM   3660 C CB  . ARG A 1 483 ? -30.17637 2.64668   25.74446  1.000 56.04831  ? 482 ARG A CB  1 
ATOM   3661 N N   . ARG A 1 484 ? -30.06120 0.64439   23.13174  1.000 57.09251  ? 483 ARG A N   1 
ATOM   3662 C CA  . ARG A 1 484 ? -30.31216 0.38277   21.71558  1.000 61.98478  ? 483 ARG A CA  1 
ATOM   3663 C C   . ARG A 1 484 ? -31.54064 -0.51534  21.53396  1.000 61.12051  ? 483 ARG A C   1 
ATOM   3664 O O   . ARG A 1 484 ? -32.35168 -0.30150  20.62399  1.000 53.89671  ? 483 ARG A O   1 
ATOM   3665 C CB  . ARG A 1 484 ? -29.04393 -0.22733  21.08341  1.000 58.76717  ? 483 ARG A CB  1 
ATOM   3666 C CG  . ARG A 1 484 ? -29.24891 -1.21988  19.93812  1.000 58.83910  ? 483 ARG A CG  1 
ATOM   3667 C CD  . ARG A 1 484 ? -27.92787 -1.58929  19.21620  1.000 58.49439  ? 483 ARG A CD  1 
ATOM   3668 N NE  . ARG A 1 484 ? -26.90857 -2.21924  20.05872  1.000 63.73649  ? 483 ARG A NE  1 
ATOM   3669 C CZ  . ARG A 1 484 ? -26.42429 -3.44993  19.88705  1.000 60.51389  ? 483 ARG A CZ  1 
ATOM   3670 N NH1 . ARG A 1 484 ? -26.90839 -4.26729  18.96258  1.000 55.58390  ? 483 ARG A NH1 1 
ATOM   3671 N NH2 . ARG A 1 484 ? -25.43257 -3.87544  20.66978  1.000 52.13094  ? 483 ARG A NH2 1 
ATOM   3672 N N   . ALA A 1 485 ? -31.73028 -1.47445  22.45328  1.000 61.64473  ? 484 ALA A N   1 
ATOM   3673 C CA  . ALA A 1 485 ? -32.71928 -2.53852  22.34465  1.000 47.46503  ? 484 ALA A CA  1 
ATOM   3674 C C   . ALA A 1 485 ? -34.09657 -2.15569  22.86466  1.000 50.92825  ? 484 ALA A C   1 
ATOM   3675 O O   . ALA A 1 485 ? -35.07646 -2.83646  22.54377  1.000 54.07768  ? 484 ALA A O   1 
ATOM   3676 C CB  . ALA A 1 485 ? -32.22699 -3.77211  23.10377  1.000 40.63441  ? 484 ALA A CB  1 
ATOM   3677 N N   . VAL A 1 486 ? -34.20120 -1.10308  23.66977  1.000 51.82539  ? 485 VAL A N   1 
ATOM   3678 C CA  . VAL A 1 486 ? -35.49429 -0.70115  24.20127  1.000 47.72908  ? 485 VAL A CA  1 
ATOM   3679 C C   . VAL A 1 486 ? -36.32625 -0.09139  23.08363  1.000 52.93495  ? 485 VAL A C   1 
ATOM   3680 O O   . VAL A 1 486 ? -35.79340 0.58213   22.19012  1.000 68.65857  ? 485 VAL A O   1 
ATOM   3681 C CB  . VAL A 1 486 ? -35.28366 0.26735   25.37482  1.000 52.22202  ? 485 VAL A CB  1 
ATOM   3682 C CG1 . VAL A 1 486 ? -36.59780 0.81878   25.85815  1.000 55.88277  ? 485 VAL A CG1 1 
ATOM   3683 C CG2 . VAL A 1 486 ? -34.55115 -0.44884  26.52325  1.000 45.05843  ? 485 VAL A CG2 1 
ATOM   3684 N N   . THR A 1 487 ? -37.63558 -0.34728  23.09960  1.000 48.76657  ? 486 THR A N   1 
ATOM   3685 C CA  . THR A 1 487 ? -38.46621 0.02792   21.95432  1.000 55.58584  ? 486 THR A CA  1 
ATOM   3686 C C   . THR A 1 487 ? -39.94294 -0.01385  22.34441  1.000 57.37820  ? 486 THR A C   1 
ATOM   3687 O O   . THR A 1 487 ? -40.51276 -1.10000  22.47208  1.000 63.35200  ? 486 THR A O   1 
ATOM   3688 C CB  . THR A 1 487 ? -38.18020 -0.90391  20.77325  1.000 53.63703  ? 486 THR A CB  1 
ATOM   3689 N N   . GLU A 1 488 ? -40.56884 1.15318   22.50156  1.000 54.88398  ? 487 GLU A N   1 
ATOM   3690 C CA  . GLU A 1 488 ? -41.99377 1.20481   22.80792  1.000 55.92260  ? 487 GLU A CA  1 
ATOM   3691 C C   . GLU A 1 488 ? -42.81103 0.65754   21.63979  1.000 69.34181  ? 487 GLU A C   1 
ATOM   3692 O O   . GLU A 1 488 ? -42.34315 0.59597   20.49813  1.000 75.79262  ? 487 GLU A O   1 
ATOM   3693 C CB  . GLU A 1 488 ? -42.42962 2.63692   23.12136  1.000 53.59930  ? 487 GLU A CB  1 
ATOM   3694 N N   . GLU A 1 489 ? -44.04884 0.25083   21.93712  1.000 73.49389  ? 488 GLU A N   1 
ATOM   3695 C CA  . GLU A 1 489 ? -44.95629 -0.27672  20.91887  1.000 67.97535  ? 488 GLU A CA  1 
ATOM   3696 C C   . GLU A 1 489 ? -46.38582 -0.26614  21.45368  1.000 72.82163  ? 488 GLU A C   1 
ATOM   3697 O O   . GLU A 1 489 ? -46.61883 -0.47717  22.65060  1.000 67.77432  ? 488 GLU A O   1 
ATOM   3698 C CB  . GLU A 1 489 ? -44.56924 -1.70142  20.49085  1.000 63.17284  ? 488 GLU A CB  1 
ATOM   3699 C CG  . GLU A 1 489 ? -45.08388 -2.10207  19.11546  1.000 68.15220  ? 488 GLU A CG  1 
ATOM   3700 C CD  . GLU A 1 489 ? -44.21463 -1.56547  17.98513  1.000 72.93707  ? 488 GLU A CD  1 
ATOM   3701 O OE1 . GLU A 1 489 ? -44.21858 -0.32902  17.77281  1.000 74.79098  ? 488 GLU A OE1 1 
ATOM   3702 O OE2 . GLU A 1 489 ? -43.53342 -2.37942  17.30750  1.000 65.87189  ? 488 GLU A OE2 1 
ATOM   3703 N N   . ALA A 1 490 ? -47.33968 -0.03713  20.54762  1.000 68.65803  ? 489 ALA A N   1 
ATOM   3704 C CA  . ALA A 1 490 ? -48.74794 -0.03367  20.92580  1.000 61.12226  ? 489 ALA A CA  1 
ATOM   3705 C C   . ALA A 1 490 ? -49.22023 -1.43445  21.28979  1.000 61.58527  ? 489 ALA A C   1 
ATOM   3706 O O   . ALA A 1 490 ? -48.84295 -2.42277  20.65377  1.000 65.78831  ? 489 ALA A O   1 
ATOM   3707 C CB  . ALA A 1 490 ? -49.61055 0.51462   19.79176  1.000 59.59491  ? 489 ALA A CB  1 
ATOM   3708 N N   . ASP A 1 491 ? -50.05644 -1.51107  22.32476  1.000 60.37222  ? 490 ASP A N   1 
ATOM   3709 C CA  . ASP A 1 491 ? -50.68581 -2.77479  22.68670  1.000 56.87339  ? 490 ASP A CA  1 
ATOM   3710 C C   . ASP A 1 491 ? -51.49246 -3.35179  21.53268  1.000 59.44946  ? 490 ASP A C   1 
ATOM   3711 O O   . ASP A 1 491 ? -51.61076 -4.57854  21.41004  1.000 60.08448  ? 490 ASP A O   1 
ATOM   3712 C CB  . ASP A 1 491 ? -51.58802 -2.57229  23.90059  1.000 62.72349  ? 490 ASP A CB  1 
ATOM   3713 C CG  . ASP A 1 491 ? -50.81137 -2.46611  25.19669  1.000 66.28418  ? 490 ASP A CG  1 
ATOM   3714 O OD1 . ASP A 1 491 ? -49.56072 -2.52867  25.14020  1.000 66.82409  ? 490 ASP A OD1 1 
ATOM   3715 O OD2 . ASP A 1 491 ? -51.45899 -2.32780  26.26676  1.000 65.82186  ? 490 ASP A OD2 1 
ATOM   3716 N N   . GLU A 1 492 ? -52.04970 -2.48347  20.67936  1.000 64.57134  ? 491 GLU A N   1 
ATOM   3717 C CA  . GLU A 1 492 ? -52.84559 -2.93719  19.54085  1.000 62.68247  ? 491 GLU A CA  1 
ATOM   3718 C C   . GLU A 1 492 ? -52.03806 -3.82502  18.58965  1.000 59.81631  ? 491 GLU A C   1 
ATOM   3719 O O   . GLU A 1 492 ? -52.61746 -4.68442  17.91233  1.000 59.47835  ? 491 GLU A O   1 
ATOM   3720 C CB  . GLU A 1 492 ? -53.42021 -1.72401  18.79224  1.000 56.82010  ? 491 GLU A CB  1 
ATOM   3721 N N   . ILE A 1 493 ? -50.71191 -3.64279  18.52271  1.000 51.70894  ? 492 ILE A N   1 
ATOM   3722 C CA  . ILE A 1 493 ? -49.86899 -4.38562  17.59484  1.000 52.38049  ? 492 ILE A CA  1 
ATOM   3723 C C   . ILE A 1 493 ? -48.79374 -5.20461  18.30072  1.000 53.45202  ? 492 ILE A C   1 
ATOM   3724 O O   . ILE A 1 493 ? -47.87118 -5.68273  17.64839  1.000 53.84493  ? 492 ILE A O   1 
ATOM   3725 C CB  . ILE A 1 493 ? -49.22115 -3.46298  16.54141  1.000 53.22657  ? 492 ILE A CB  1 
ATOM   3726 C CG1 . ILE A 1 493 ? -48.16816 -2.55748  17.17639  1.000 53.55235  ? 492 ILE A CG1 1 
ATOM   3727 C CG2 . ILE A 1 493 ? -50.26459 -2.64395  15.81842  1.000 52.37860  ? 492 ILE A CG2 1 
ATOM   3728 C CD1 . ILE A 1 493 ? -47.32850 -1.83809  16.14472  1.000 56.57149  ? 492 ILE A CD1 1 
ATOM   3729 N N   . ARG A 1 494 ? -48.88877 -5.38857  19.62211  1.000 58.15906  ? 493 ARG A N   1 
ATOM   3730 C CA  . ARG A 1 494 ? -47.91962 -6.24696  20.30831  1.000 50.10429  ? 493 ARG A CA  1 
ATOM   3731 C C   . ARG A 1 494 ? -48.04987 -7.70470  19.87322  1.000 47.90117  ? 493 ARG A C   1 
ATOM   3732 O O   . ARG A 1 494 ? -47.04614 -8.42542  19.81043  1.000 39.77139  ? 493 ARG A O   1 
ATOM   3733 C CB  . ARG A 1 494 ? -48.08126 -6.12915  21.82747  1.000 46.45979  ? 493 ARG A CB  1 
ATOM   3734 C CG  . ARG A 1 494 ? -46.92448 -6.68426  22.65723  1.000 41.15015  ? 493 ARG A CG  1 
ATOM   3735 C CD  . ARG A 1 494 ? -45.68764 -5.78887  22.59835  1.000 47.71560  ? 493 ARG A CD  1 
ATOM   3736 N NE  . ARG A 1 494 ? -45.61640 -4.80498  23.67735  1.000 51.97273  ? 493 ARG A NE  1 
ATOM   3737 C CZ  . ARG A 1 494 ? -45.29931 -5.07888  24.93732  1.000 54.37110  ? 493 ARG A CZ  1 
ATOM   3738 N NH1 . ARG A 1 494 ? -45.05061 -6.31860  25.34348  1.000 56.23177  ? 493 ARG A NH1 1 
ATOM   3739 N NH2 . ARG A 1 494 ? -45.22033 -4.08499  25.81397  1.000 60.51399  ? 493 ARG A NH2 1 
ATOM   3740 N N   . ASN A 1 495 ? -49.26606 -8.15487  19.55216  1.000 48.34372  ? 494 ASN A N   1 
ATOM   3741 C CA  . ASN A 1 495 ? -49.45010 -9.54687  19.16615  1.000 43.27172  ? 494 ASN A CA  1 
ATOM   3742 C C   . ASN A 1 495 ? -48.82369 -9.88470  17.81468  1.000 43.03316  ? 494 ASN A C   1 
ATOM   3743 O O   . ASN A 1 495 ? -48.73977 -11.06928 17.47143  1.000 42.49338  ? 494 ASN A O   1 
ATOM   3744 C CB  . ASN A 1 495 ? -50.93680 -9.88881  19.17836  1.000 39.21207  ? 494 ASN A CB  1 
ATOM   3745 C CG  . ASN A 1 495 ? -51.70303 -9.24989  18.03905  1.000 44.86302  ? 494 ASN A CG  1 
ATOM   3746 O OD1 . ASN A 1 495 ? -51.18622 -8.40163  17.28375  1.000 48.25454  ? 494 ASN A OD1 1 
ATOM   3747 N ND2 . ASN A 1 495 ? -52.96321 -9.65089  17.91004  1.000 38.89712  ? 494 ASN A ND2 1 
ATOM   3748 N N   . LEU A 1 496 ? -48.37657 -8.88703  17.04928  1.000 40.63243  ? 495 LEU A N   1 
ATOM   3749 C CA  . LEU A 1 496 ? -47.63331 -9.14776  15.82160  1.000 42.07242  ? 495 LEU A CA  1 
ATOM   3750 C C   . LEU A 1 496 ? -46.33592 -9.90532  16.04837  1.000 41.41372  ? 495 LEU A C   1 
ATOM   3751 O O   . LEU A 1 496 ? -45.73663 -10.37457 15.07594  1.000 40.57830  ? 495 LEU A O   1 
ATOM   3752 C CB  . LEU A 1 496 ? -47.29361 -7.84493  15.12462  1.000 40.89763  ? 495 LEU A CB  1 
ATOM   3753 C CG  . LEU A 1 496 ? -48.46035 -7.12131  14.49636  1.000 41.32311  ? 495 LEU A CG  1 
ATOM   3754 C CD1 . LEU A 1 496 ? -47.87516 -6.20352  13.47451  1.000 44.54998  ? 495 LEU A CD1 1 
ATOM   3755 C CD2 . LEU A 1 496 ? -49.43606 -8.11232  13.87681  1.000 37.70940  ? 495 LEU A CD2 1 
ATOM   3756 N N   . GLY A 1 497 ? -45.86167 -10.00593 17.28686  1.000 41.68496  ? 496 GLY A N   1 
ATOM   3757 C CA  . GLY A 1 497 ? -44.61771 -10.71303 17.51683  1.000 40.71828  ? 496 GLY A CA  1 
ATOM   3758 C C   . GLY A 1 497 ? -44.74646 -12.18198 17.21274  1.000 41.64423  ? 496 GLY A C   1 
ATOM   3759 O O   . GLY A 1 497 ? -43.75892 -12.84151 16.88224  1.000 48.61458  ? 496 GLY A O   1 
ATOM   3760 N N   . VAL A 1 498 ? -45.95691 -12.71259 17.32870  1.000 39.90092  ? 497 VAL A N   1 
ATOM   3761 C CA  . VAL A 1 498 ? -46.25982 -14.07426 16.93564  1.000 36.17709  ? 497 VAL A CA  1 
ATOM   3762 C C   . VAL A 1 498 ? -47.00442 -14.11281 15.60923  1.000 39.50583  ? 497 VAL A C   1 
ATOM   3763 O O   . VAL A 1 498 ? -46.66662 -14.90750 14.73216  1.000 41.29643  ? 497 VAL A O   1 
ATOM   3764 C CB  . VAL A 1 498 ? -47.07152 -14.76387 18.05335  1.000 38.22082  ? 497 VAL A CB  1 
ATOM   3765 C CG1 . VAL A 1 498 ? -47.88164 -15.91817 17.50449  1.000 40.48155  ? 497 VAL A CG1 1 
ATOM   3766 C CG2 . VAL A 1 498 ? -46.15624 -15.24919 19.15687  1.000 42.04647  ? 497 VAL A CG2 1 
ATOM   3767 N N   . LEU A 1 499 ? -47.99608 -13.22980 15.44137  1.000 37.18424  ? 498 LEU A N   1 
ATOM   3768 C CA  . LEU A 1 499 ? -48.91995 -13.33480 14.31484  1.000 38.98208  ? 498 LEU A CA  1 
ATOM   3769 C C   . LEU A 1 499 ? -48.24876 -13.00097 12.98542  1.000 42.83944  ? 498 LEU A C   1 
ATOM   3770 O O   . LEU A 1 499 ? -48.53944 -13.64096 11.97015  1.000 43.75332  ? 498 LEU A O   1 
ATOM   3771 C CB  . LEU A 1 499 ? -50.12915 -12.42845 14.53673  1.000 41.19544  ? 498 LEU A CB  1 
ATOM   3772 C CG  . LEU A 1 499 ? -51.11833 -12.79402 15.64751  1.000 39.27800  ? 498 LEU A CG  1 
ATOM   3773 C CD1 . LEU A 1 499 ? -52.29393 -11.82285 15.62633  1.000 35.34772  ? 498 LEU A CD1 1 
ATOM   3774 C CD2 . LEU A 1 499 ? -51.60455 -14.24624 15.54340  1.000 35.29903  ? 498 LEU A CD2 1 
ATOM   3775 N N   . SER A 1 500 ? -47.37404 -11.99093 12.94928  1.000 43.38196  ? 499 SER A N   1 
ATOM   3776 C CA  . SER A 1 500 ? -46.62909 -11.73903 11.71549  1.000 40.08102  ? 499 SER A CA  1 
ATOM   3777 C C   . SER A 1 500 ? -45.26740 -12.42262 11.72324  1.000 40.69578  ? 499 SER A C   1 
ATOM   3778 O O   . SER A 1 500 ? -44.90516 -13.07131 10.74436  1.000 46.97631  ? 499 SER A O   1 
ATOM   3779 C CB  . SER A 1 500 ? -46.45099 -10.23523 11.45981  1.000 41.54542  ? 499 SER A CB  1 
ATOM   3780 O OG  . SER A 1 500 ? -45.22287 -9.97983  10.76947  1.000 44.50439  ? 499 SER A OG  1 
ATOM   3781 N N   . ASP A 1 501 ? -44.51084 -12.30577 12.81934  1.000 47.88676  ? 500 ASP A N   1 
ATOM   3782 C CA  . ASP A 1 501 ? -43.16186 -12.86615 12.85106  1.000 43.53809  ? 500 ASP A CA  1 
ATOM   3783 C C   . ASP A 1 501 ? -43.17062 -14.38240 12.71906  1.000 42.41889  ? 500 ASP A C   1 
ATOM   3784 O O   . ASP A 1 501 ? -42.29063 -14.94527 12.06057  1.000 47.43997  ? 500 ASP A O   1 
ATOM   3785 C CB  . ASP A 1 501 ? -42.43171 -12.45017 14.12294  1.000 38.00976  ? 500 ASP A CB  1 
ATOM   3786 C CG  . ASP A 1 501 ? -42.01707 -10.98411 14.09560  1.000 51.96857  ? 500 ASP A CG  1 
ATOM   3787 O OD1 . ASP A 1 501 ? -42.31181 -10.32131 13.07698  1.000 56.24113  ? 500 ASP A OD1 1 
ATOM   3788 O OD2 . ASP A 1 501 ? -41.39829 -10.49241 15.07423  1.000 61.22994  ? 500 ASP A OD2 1 
ATOM   3789 N N   . VAL A 1 502 ? -44.15660 -15.06625 13.30369  1.000 36.83257  ? 501 VAL A N   1 
ATOM   3790 C CA  . VAL A 1 502 ? -44.20257 -16.52994 13.28855  1.000 37.30032  ? 501 VAL A CA  1 
ATOM   3791 C C   . VAL A 1 502 ? -45.29345 -17.06357 12.35478  1.000 39.88640  ? 501 VAL A C   1 
ATOM   3792 O O   . VAL A 1 502 ? -45.01185 -17.84788 11.44298  1.000 37.19120  ? 501 VAL A O   1 
ATOM   3793 C CB  . VAL A 1 502 ? -44.34787 -17.10610 14.71315  1.000 35.00395  ? 501 VAL A CB  1 
ATOM   3794 C CG1 . VAL A 1 502 ? -44.61141 -18.57629 14.63158  1.000 33.87928  ? 501 VAL A CG1 1 
ATOM   3795 C CG2 . VAL A 1 502 ? -43.07456 -16.87964 15.48242  1.000 35.89164  ? 501 VAL A CG2 1 
ATOM   3796 N N   . PHE A 1 503 ? -46.55111 -16.68354 12.58724  1.000 43.67167  ? 502 PHE A N   1 
ATOM   3797 C CA  . PHE A 1 503 ? -47.62810 -17.22973 11.76248  1.000 38.59239  ? 502 PHE A CA  1 
ATOM   3798 C C   . PHE A 1 503 ? -47.42553 -16.85545 10.29961  1.000 35.84471  ? 502 PHE A C   1 
ATOM   3799 O O   . PHE A 1 503 ? -47.19907 -17.72370 9.45687   1.000 39.87301  ? 502 PHE A O   1 
ATOM   3800 C CB  . PHE A 1 503 ? -49.00073 -16.77002 12.27043  1.000 33.37540  ? 502 PHE A CB  1 
ATOM   3801 C CG  . PHE A 1 503 ? -49.46086 -17.48649 13.50768  1.000 35.28763  ? 502 PHE A CG  1 
ATOM   3802 C CD1 . PHE A 1 503 ? -48.60661 -18.34397 14.19997  1.000 37.52793  ? 502 PHE A CD1 1 
ATOM   3803 C CD2 . PHE A 1 503 ? -50.74393 -17.31332 13.98493  1.000 34.59199  ? 502 PHE A CD2 1 
ATOM   3804 C CE1 . PHE A 1 503 ? -49.03158 -19.01588 15.34783  1.000 31.52348  ? 502 PHE A CE1 1 
ATOM   3805 C CE2 . PHE A 1 503 ? -51.17063 -17.97617 15.13249  1.000 31.68705  ? 502 PHE A CE2 1 
ATOM   3806 C CZ  . PHE A 1 503 ? -50.30776 -18.82700 15.80876  1.000 30.10288  ? 502 PHE A CZ  1 
ATOM   3807 N N   . ASP A 1 504 ? -47.45608 -15.56180 9.97802   1.000 40.31021  ? 503 ASP A N   1 
ATOM   3808 C CA  . ASP A 1 504 ? -47.46617 -15.19988 8.56366   1.000 42.20069  ? 503 ASP A CA  1 
ATOM   3809 C C   . ASP A 1 504 ? -46.09984 -15.33924 7.90427   1.000 44.03848  ? 503 ASP A C   1 
ATOM   3810 O O   . ASP A 1 504 ? -46.03831 -15.56594 6.68998   1.000 44.53519  ? 503 ASP A O   1 
ATOM   3811 C CB  . ASP A 1 504 ? -47.96828 -13.77613 8.34867   1.000 39.61726  ? 503 ASP A CB  1 
ATOM   3812 C CG  . ASP A 1 504 ? -48.11670 -13.44950 6.87183   1.000 48.24343  ? 503 ASP A CG  1 
ATOM   3813 O OD1 . ASP A 1 504 ? -49.00660 -14.06716 6.24599   1.000 46.05982  ? 503 ASP A OD1 1 
ATOM   3814 O OD2 . ASP A 1 504 ? -47.33036 -12.62831 6.32485   1.000 47.03896  ? 503 ASP A OD2 1 
ATOM   3815 N N   . ASP A 1 505 ? -45.00244 -15.21199 8.66227   1.000 42.02926  ? 504 ASP A N   1 
ATOM   3816 C CA  . ASP A 1 505 ? -43.67046 -15.26911 8.06261   1.000 39.78717  ? 504 ASP A CA  1 
ATOM   3817 C C   . ASP A 1 505 ? -43.06153 -16.66853 8.03501   1.000 38.75546  ? 504 ASP A C   1 
ATOM   3818 O O   . ASP A 1 505 ? -42.12872 -16.88928 7.26369   1.000 41.99017  ? 504 ASP A O   1 
ATOM   3819 C CB  . ASP A 1 505 ? -42.69090 -14.33465 8.78785   1.000 41.07723  ? 504 ASP A CB  1 
ATOM   3820 C CG  . ASP A 1 505 ? -42.89744 -12.85181 8.44608   1.000 51.47684  ? 504 ASP A CG  1 
ATOM   3821 O OD1 . ASP A 1 505 ? -43.58955 -12.50418 7.46077   1.000 54.89116  ? 504 ASP A OD1 1 
ATOM   3822 O OD2 . ASP A 1 505 ? -42.36417 -12.01402 9.20006   1.000 57.58310  ? 504 ASP A OD2 1 
ATOM   3823 N N   . PHE A 1 506 ? -43.53244 -17.61883 8.84872   1.000 36.40804  ? 505 PHE A N   1 
ATOM   3824 C CA  . PHE A 1 506 ? -42.95254 -18.95734 8.78002   1.000 29.94344  ? 505 PHE A CA  1 
ATOM   3825 C C   . PHE A 1 506 ? -43.99230 -20.07643 8.72637   1.000 33.45090  ? 505 PHE A C   1 
ATOM   3826 O O   . PHE A 1 506 ? -43.95332 -20.91002 7.81699   1.000 33.57630  ? 505 PHE A O   1 
ATOM   3827 C CB  . PHE A 1 506 ? -42.00346 -19.21933 9.94869   1.000 26.82517  ? 505 PHE A CB  1 
ATOM   3828 C CG  . PHE A 1 506 ? -41.22479 -20.49339 9.79027   1.000 30.60901  ? 505 PHE A CG  1 
ATOM   3829 C CD1 . PHE A 1 506 ? -40.00978 -20.50233 9.12135   1.000 30.27570  ? 505 PHE A CD1 1 
ATOM   3830 C CD2 . PHE A 1 506 ? -41.74260 -21.70427 10.25072  1.000 32.89216  ? 505 PHE A CD2 1 
ATOM   3831 C CE1 . PHE A 1 506 ? -39.30372 -21.68698 8.93531   1.000 31.09292  ? 505 PHE A CE1 1 
ATOM   3832 C CE2 . PHE A 1 506 ? -41.04525 -22.90102 10.07146  1.000 32.26659  ? 505 PHE A CE2 1 
ATOM   3833 C CZ  . PHE A 1 506 ? -39.82161 -22.89242 9.41065   1.000 33.09862  ? 505 PHE A CZ  1 
ATOM   3834 N N   . LEU A 1 507 ? -44.90220 -20.15001 9.69881   1.000 32.71815  ? 506 LEU A N   1 
ATOM   3835 C CA  . LEU A 1 507 ? -45.84574 -21.26682 9.69505   1.000 32.72399  ? 506 LEU A CA  1 
ATOM   3836 C C   . LEU A 1 507 ? -46.70123 -21.29638 8.42737   1.000 33.49944  ? 506 LEU A C   1 
ATOM   3837 O O   . LEU A 1 507 ? -47.02639 -22.37845 7.93182   1.000 33.79936  ? 506 LEU A O   1 
ATOM   3838 C CB  . LEU A 1 507 ? -46.72044 -21.22809 10.94603  1.000 34.78714  ? 506 LEU A CB  1 
ATOM   3839 C CG  . LEU A 1 507 ? -45.97716 -21.65190 12.22602  1.000 35.83288  ? 506 LEU A CG  1 
ATOM   3840 C CD1 . LEU A 1 507 ? -46.92434 -21.91328 13.41052  1.000 24.92723  ? 506 LEU A CD1 1 
ATOM   3841 C CD2 . LEU A 1 507 ? -45.06961 -22.86065 11.96202  1.000 31.78664  ? 506 LEU A CD2 1 
ATOM   3842 N N   . ARG A 1 508 ? -47.05201 -20.13334 7.87114   1.000 34.22335  ? 507 ARG A N   1 
ATOM   3843 C CA  . ARG A 1 508 ? -47.75774 -20.10440 6.59273   1.000 28.51666  ? 507 ARG A CA  1 
ATOM   3844 C C   . ARG A 1 508 ? -47.01366 -20.90931 5.52639   1.000 34.10040  ? 507 ARG A C   1 
ATOM   3845 O O   . ARG A 1 508 ? -47.62751 -21.62900 4.72831   1.000 34.95144  ? 507 ARG A O   1 
ATOM   3846 C CB  . ARG A 1 508 ? -47.95164 -18.65561 6.13784   1.000 31.55565  ? 507 ARG A CB  1 
ATOM   3847 C CG  . ARG A 1 508 ? -48.22244 -18.49385 4.63998   1.000 35.56568  ? 507 ARG A CG  1 
ATOM   3848 C CD  . ARG A 1 508 ? -48.76206 -17.12317 4.25456   1.000 33.74018  ? 507 ARG A CD  1 
ATOM   3849 N NE  . ARG A 1 508 ? -47.71819 -16.10409 4.27754   1.000 40.03397  ? 507 ARG A NE  1 
ATOM   3850 C CZ  . ARG A 1 508 ? -46.84078 -15.88408 3.30679   1.000 36.45699  ? 507 ARG A CZ  1 
ATOM   3851 N NH1 . ARG A 1 508 ? -46.81219 -16.62252 2.21636   1.000 37.61532  ? 507 ARG A NH1 1 
ATOM   3852 N NH2 . ARG A 1 508 ? -45.96455 -14.89968 3.43921   1.000 41.30280  ? 507 ARG A NH2 1 
ATOM   3853 N N   . HIS A 1 509 ? -45.68801 -20.81383 5.50161   1.000 32.21959  ? 508 HIS A N   1 
ATOM   3854 C CA  . HIS A 1 509 ? -44.93766 -21.53526 4.48392   1.000 31.86162  ? 508 HIS A CA  1 
ATOM   3855 C C   . HIS A 1 509 ? -44.88101 -23.02241 4.77432   1.000 37.45304  ? 508 HIS A C   1 
ATOM   3856 O O   . HIS A 1 509 ? -44.87034 -23.83280 3.84180   1.000 39.97392  ? 508 HIS A O   1 
ATOM   3857 C CB  . HIS A 1 509 ? -43.54037 -20.95564 4.37637   1.000 30.48808  ? 508 HIS A CB  1 
ATOM   3858 C CG  . HIS A 1 509 ? -43.54561 -19.51615 3.99236   1.000 36.51017  ? 508 HIS A CG  1 
ATOM   3859 N ND1 . HIS A 1 509 ? -43.86271 -19.09132 2.72044   1.000 37.45692  ? 508 HIS A ND1 1 
ATOM   3860 C CD2 . HIS A 1 509 ? -43.32992 -18.39857 4.72110   1.000 39.83095  ? 508 HIS A CD2 1 
ATOM   3861 C CE1 . HIS A 1 509 ? -43.81700 -17.77383 2.67585   1.000 40.09079  ? 508 HIS A CE1 1 
ATOM   3862 N NE2 . HIS A 1 509 ? -43.49747 -17.32821 3.87697   1.000 43.62403  ? 508 HIS A NE2 1 
ATOM   3863 N N   . PHE A 1 510 ? -44.82975 -23.39694 6.05211   1.000 35.02308  ? 509 PHE A N   1 
ATOM   3864 C CA  . PHE A 1 510 ? -44.87120 -24.80474 6.41439   1.000 31.57543  ? 509 PHE A CA  1 
ATOM   3865 C C   . PHE A 1 510 ? -46.23014 -25.41546 6.08554   1.000 37.67631  ? 509 PHE A C   1 
ATOM   3866 O O   . PHE A 1 510 ? -46.30838 -26.58226 5.68169   1.000 35.87334  ? 509 PHE A O   1 
ATOM   3867 C CB  . PHE A 1 510 ? -44.56394 -24.94754 7.90035   1.000 34.99229  ? 509 PHE A CB  1 
ATOM   3868 C CG  . PHE A 1 510 ? -44.17480 -26.33354 8.31443   1.000 39.52717  ? 509 PHE A CG  1 
ATOM   3869 C CD1 . PHE A 1 510 ? -43.46591 -27.16370 7.44926   1.000 39.74484  ? 509 PHE A CD1 1 
ATOM   3870 C CD2 . PHE A 1 510 ? -44.50800 -26.80669 9.57698   1.000 35.44479  ? 509 PHE A CD2 1 
ATOM   3871 C CE1 . PHE A 1 510 ? -43.09173 -28.43913 7.84792   1.000 38.01131  ? 509 PHE A CE1 1 
ATOM   3872 C CE2 . PHE A 1 510 ? -44.13949 -28.07936 9.97877   1.000 32.67768  ? 509 PHE A CE2 1 
ATOM   3873 C CZ  . PHE A 1 510 ? -43.43317 -28.89306 9.12148   1.000 34.57146  ? 509 PHE A CZ  1 
ATOM   3874 N N   . ALA A 1 511 ? -47.31533 -24.64135 6.26223   1.000 37.71475  ? 510 ALA A N   1 
ATOM   3875 C CA  . ALA A 1 511 ? -48.66111 -25.17654 6.07749   1.000 29.42853  ? 510 ALA A CA  1 
ATOM   3876 C C   . ALA A 1 511 ? -48.93444 -25.47926 4.61590   1.000 35.56054  ? 510 ALA A C   1 
ATOM   3877 O O   . ALA A 1 511 ? -49.52766 -26.51385 4.29613   1.000 43.51335  ? 510 ALA A O   1 
ATOM   3878 C CB  . ALA A 1 511 ? -49.69536 -24.19776 6.61026   1.000 29.98354  ? 510 ALA A CB  1 
ATOM   3879 N N   . LEU A 1 512 ? -48.51418 -24.58818 3.71225   1.000 35.58552  ? 511 LEU A N   1 
ATOM   3880 C CA  . LEU A 1 512 ? -48.65991 -24.85230 2.28212   1.000 35.74763  ? 511 LEU A CA  1 
ATOM   3881 C C   . LEU A 1 512 ? -47.88431 -26.09640 1.88928   1.000 35.60586  ? 511 LEU A C   1 
ATOM   3882 O O   . LEU A 1 512 ? -48.39181 -26.96541 1.17387   1.000 39.04653  ? 511 LEU A O   1 
ATOM   3883 C CB  . LEU A 1 512 ? -48.17326 -23.64788 1.47435   1.000 39.16054  ? 511 LEU A CB  1 
ATOM   3884 C CG  . LEU A 1 512 ? -48.50057 -23.43015 -0.01063  1.000 39.22577  ? 511 LEU A CG  1 
ATOM   3885 C CD1 . LEU A 1 512 ? -48.01702 -22.05225 -0.41294  1.000 32.32484  ? 511 LEU A CD1 1 
ATOM   3886 C CD2 . LEU A 1 512 ? -47.89220 -24.47783 -0.93939  1.000 36.89616  ? 511 LEU A CD2 1 
ATOM   3887 N N   . LEU A 1 513 ? -46.63888 -26.18674 2.34145   1.000 32.92111  ? 512 LEU A N   1 
ATOM   3888 C CA  . LEU A 1 513 ? -45.82311 -27.34910 2.03579   1.000 29.98690  ? 512 LEU A CA  1 
ATOM   3889 C C   . LEU A 1 513 ? -46.45212 -28.63109 2.58015   1.000 37.21779  ? 512 LEU A C   1 
ATOM   3890 O O   . LEU A 1 513 ? -46.42372 -29.66947 1.91039   1.000 41.26476  ? 512 LEU A O   1 
ATOM   3891 C CB  . LEU A 1 513 ? -44.41973 -27.13529 2.59304   1.000 28.31357  ? 512 LEU A CB  1 
ATOM   3892 C CG  . LEU A 1 513 ? -43.30983 -28.10829 2.22037   1.000 33.00485  ? 512 LEU A CG  1 
ATOM   3893 C CD1 . LEU A 1 513 ? -41.99295 -27.34888 2.21755   1.000 38.36430  ? 512 LEU A CD1 1 
ATOM   3894 C CD2 . LEU A 1 513 ? -43.24128 -29.30371 3.17032   1.000 30.78626  ? 512 LEU A CD2 1 
ATOM   3895 N N   . LEU A 1 514 ? -47.03512 -28.59039 3.78564   1.000 29.78661  ? 513 LEU A N   1 
ATOM   3896 C CA  . LEU A 1 514 ? -47.64548 -29.81274 4.29753   1.000 33.34441  ? 513 LEU A CA  1 
ATOM   3897 C C   . LEU A 1 514 ? -48.96271 -30.11952 3.60134   1.000 36.89078  ? 513 LEU A C   1 
ATOM   3898 O O   . LEU A 1 514 ? -49.35850 -31.28606 3.51478   1.000 38.22343  ? 513 LEU A O   1 
ATOM   3899 C CB  . LEU A 1 514 ? -47.86720 -29.73094 5.80537   1.000 30.27177  ? 513 LEU A CB  1 
ATOM   3900 C CG  . LEU A 1 514 ? -46.57721 -29.69819 6.59233   1.000 28.94839  ? 513 LEU A CG  1 
ATOM   3901 C CD1 . LEU A 1 514 ? -46.80428 -29.11692 7.97154   1.000 31.68244  ? 513 LEU A CD1 1 
ATOM   3902 C CD2 . LEU A 1 514 ? -46.01837 -31.07969 6.65998   1.000 27.08731  ? 513 LEU A CD2 1 
ATOM   3903 N N   . HIS A 1 515 ? -49.65755 -29.09788 3.11264   1.000 32.34908  ? 514 HIS A N   1 
ATOM   3904 C CA  . HIS A 1 515 ? -50.95070 -29.32873 2.48784   1.000 38.52028  ? 514 HIS A CA  1 
ATOM   3905 C C   . HIS A 1 515 ? -50.80154 -29.76245 1.03318   1.000 42.05801  ? 514 HIS A C   1 
ATOM   3906 O O   . HIS A 1 515 ? -51.49624 -30.68029 0.56876   1.000 38.66284  ? 514 HIS A O   1 
ATOM   3907 C CB  . HIS A 1 515 ? -51.79021 -28.06154 2.59175   1.000 39.77859  ? 514 HIS A CB  1 
ATOM   3908 C CG  . HIS A 1 515 ? -52.97816 -28.04856 1.68482   1.000 43.95690  ? 514 HIS A CG  1 
ATOM   3909 N ND1 . HIS A 1 515 ? -54.23818 -28.41657 2.10570   1.000 41.86243  ? 514 HIS A ND1 1 
ATOM   3910 C CD2 . HIS A 1 515 ? -53.09809 -27.70668 0.37779   1.000 43.24375  ? 514 HIS A CD2 1 
ATOM   3911 C CE1 . HIS A 1 515 ? -55.08463 -28.28889 1.09841   1.000 46.56940  ? 514 HIS A CE1 1 
ATOM   3912 N NE2 . HIS A 1 515 ? -54.41946 -27.85757 0.03937   1.000 46.82179  ? 514 HIS A NE2 1 
ATOM   3913 N N   . GLU A 1 516 ? -49.90128 -29.10187 0.30466   1.000 43.43126  ? 515 GLU A N   1 
ATOM   3914 C CA  . GLU A 1 516 ? -49.64277 -29.47725 -1.07645  1.000 42.54874  ? 515 GLU A CA  1 
ATOM   3915 C C   . GLU A 1 516 ? -49.18392 -30.92093 -1.17327  1.000 39.66913  ? 515 GLU A C   1 
ATOM   3916 O O   . GLU A 1 516 ? -49.53964 -31.61664 -2.12704  1.000 43.95761  ? 515 GLU A O   1 
ATOM   3917 C CB  . GLU A 1 516 ? -48.61385 -28.52384 -1.68391  1.000 39.34987  ? 515 GLU A CB  1 
ATOM   3918 C CG  . GLU A 1 516 ? -47.77598 -29.09942 -2.79556  1.000 43.97113  ? 515 GLU A CG  1 
ATOM   3919 C CD  . GLU A 1 516 ? -46.67478 -28.13999 -3.24129  1.000 56.11567  ? 515 GLU A CD  1 
ATOM   3920 O OE1 . GLU A 1 516 ? -46.92008 -26.90985 -3.22270  1.000 47.45277  ? 515 GLU A OE1 1 
ATOM   3921 O OE2 . GLU A 1 516 ? -45.57311 -28.61961 -3.61960  1.000 70.65114  ? 515 GLU A OE2 1 
ATOM   3922 N N   . SER A 1 517 ? -48.44013 -31.40136 -0.18226  1.000 37.39642  ? 516 SER A N   1 
ATOM   3923 C CA  . SER A 1 517 ? -47.91796 -32.76082 -0.19839  1.000 38.71435  ? 516 SER A CA  1 
ATOM   3924 C C   . SER A 1 517 ? -48.87245 -33.77514 0.38828   1.000 38.51375  ? 516 SER A C   1 
ATOM   3925 O O   . SER A 1 517 ? -48.51336 -34.94579 0.47554   1.000 41.58854  ? 516 SER A O   1 
ATOM   3926 C CB  . SER A 1 517 ? -46.61300 -32.83963 0.57808   1.000 39.59990  ? 516 SER A CB  1 
ATOM   3927 O OG  . SER A 1 517 ? -45.74525 -31.82375 0.13288   1.000 50.05372  ? 516 SER A OG  1 
ATOM   3928 N N   . GLY A 1 518 ? -50.05555 -33.36462 0.82183   1.000 37.69836  ? 517 GLY A N   1 
ATOM   3929 C CA  . GLY A 1 518 ? -50.96389 -34.33586 1.38753   1.000 38.35470  ? 517 GLY A CA  1 
ATOM   3930 C C   . GLY A 1 518 ? -50.63426 -34.82280 2.78036   1.000 40.54207  ? 517 GLY A C   1 
ATOM   3931 O O   . GLY A 1 518 ? -51.34356 -35.69390 3.29482   1.000 40.95840  ? 517 GLY A O   1 
ATOM   3932 N N   . LEU A 1 519 ? -49.59620 -34.27072 3.41925   1.000 44.27876  ? 518 LEU A N   1 
ATOM   3933 C CA  . LEU A 1 519 ? -49.22659 -34.66959 4.77701   1.000 37.77144  ? 518 LEU A CA  1 
ATOM   3934 C C   . LEU A 1 519 ? -50.15238 -34.07524 5.84133   1.000 39.33930  ? 518 LEU A C   1 
ATOM   3935 O O   . LEU A 1 519 ? -50.35058 -34.69163 6.89619   1.000 41.43974  ? 518 LEU A O   1 
ATOM   3936 C CB  . LEU A 1 519 ? -47.77510 -34.26836 5.04942   1.000 35.55248  ? 518 LEU A CB  1 
ATOM   3937 C CG  . LEU A 1 519 ? -46.73542 -35.29183 4.60112   1.000 31.36894  ? 518 LEU A CG  1 
ATOM   3938 C CD1 . LEU A 1 519 ? -45.37815 -34.66003 4.35825   1.000 24.39090  ? 518 LEU A CD1 1 
ATOM   3939 C CD2 . LEU A 1 519 ? -46.65373 -36.35990 5.65894   1.000 37.99366  ? 518 LEU A CD2 1 
ATOM   3940 N N   . LEU A 1 520 ? -50.71804 -32.89171 5.60069   1.000 34.69650  ? 519 LEU A N   1 
ATOM   3941 C CA  . LEU A 1 520 ? -51.67523 -32.31099 6.53267   1.000 36.11212  ? 519 LEU A CA  1 
ATOM   3942 C C   . LEU A 1 520 ? -52.42883 -31.17339 5.84981   1.000 40.25914  ? 519 LEU A C   1 
ATOM   3943 O O   . LEU A 1 520 ? -51.80922 -30.23951 5.32939   1.000 40.73734  ? 519 LEU A O   1 
ATOM   3944 C CB  . LEU A 1 520 ? -50.96222 -31.81754 7.79932   1.000 41.09388  ? 519 LEU A CB  1 
ATOM   3945 C CG  . LEU A 1 520 ? -51.76913 -31.62897 9.09753   1.000 39.83312  ? 519 LEU A CG  1 
ATOM   3946 C CD1 . LEU A 1 520 ? -52.22970 -32.93341 9.66793   1.000 39.93596  ? 519 LEU A CD1 1 
ATOM   3947 C CD2 . LEU A 1 520 ? -50.97744 -30.86969 10.13770  1.000 36.63868  ? 519 LEU A CD2 1 
ATOM   3948 N N   . THR A 1 521 ? -53.75887 -31.24191 5.82786   1.000 38.49121  ? 520 THR A N   1 
ATOM   3949 C CA  . THR A 1 521 ? -54.53350 -30.22136 5.13801   1.000 39.47880  ? 520 THR A CA  1 
ATOM   3950 C C   . THR A 1 521 ? -54.46147 -28.91489 5.91376   1.000 41.58088  ? 520 THR A C   1 
ATOM   3951 O O   . THR A 1 521 ? -54.35114 -28.91168 7.14481   1.000 38.83015  ? 520 THR A O   1 
ATOM   3952 C CB  . THR A 1 521 ? -55.99502 -30.66102 4.95993   1.000 38.93969  ? 520 THR A CB  1 
ATOM   3953 O OG1 . THR A 1 521 ? -56.66125 -30.66417 6.22360   1.000 38.91428  ? 520 THR A OG1 1 
ATOM   3954 C CG2 . THR A 1 521 ? -56.07588 -32.05514 4.39547   1.000 38.67509  ? 520 THR A CG2 1 
ATOM   3955 N N   . ASP A 1 522 ? -54.52323 -27.79498 5.17352   1.000 38.35483  ? 521 ASP A N   1 
ATOM   3956 C CA  . ASP A 1 522 ? -54.41521 -26.47281 5.78789   1.000 34.41702  ? 521 ASP A CA  1 
ATOM   3957 C C   . ASP A 1 522 ? -55.31161 -26.33352 7.01803   1.000 32.86779  ? 521 ASP A C   1 
ATOM   3958 O O   . ASP A 1 522 ? -54.93110 -25.68517 7.99215   1.000 33.05804  ? 521 ASP A O   1 
ATOM   3959 C CB  . ASP A 1 522 ? -54.74897 -25.41053 4.74638   1.000 33.29750  ? 521 ASP A CB  1 
ATOM   3960 C CG  . ASP A 1 522 ? -54.60267 -23.98455 5.27691   1.000 39.50608  ? 521 ASP A CG  1 
ATOM   3961 O OD1 . ASP A 1 522 ? -53.48210 -23.57745 5.69520   1.000 39.76420  ? 521 ASP A OD1 1 
ATOM   3962 O OD2 . ASP A 1 522 ? -55.62524 -23.26306 5.25755   1.000 35.44378  ? 521 ASP A OD2 1 
ATOM   3963 N N   . GLY A 1 523 ? -56.47918 -26.97259 7.00703   1.000 33.67957  ? 522 GLY A N   1 
ATOM   3964 C CA  . GLY A 1 523 ? -57.36415 -26.92300 8.15859   1.000 29.56182  ? 522 GLY A CA  1 
ATOM   3965 C C   . GLY A 1 523 ? -56.84732 -27.68461 9.36876   1.000 33.87776  ? 522 GLY A C   1 
ATOM   3966 O O   . GLY A 1 523 ? -56.87871 -27.16611 10.48452  1.000 39.85922  ? 522 GLY A O   1 
ATOM   3967 N N   . GLU A 1 524 ? -56.39562 -28.93342 9.18864   1.000 34.64007  ? 523 GLU A N   1 
ATOM   3968 C CA  . GLU A 1 524 ? -55.83404 -29.64184 10.34546  1.000 36.71129  ? 523 GLU A CA  1 
ATOM   3969 C C   . GLU A 1 524 ? -54.60856 -28.91371 10.89803  1.000 37.57150  ? 523 GLU A C   1 
ATOM   3970 O O   . GLU A 1 524 ? -54.35315 -28.95465 12.10856  1.000 34.76469  ? 523 GLU A O   1 
ATOM   3971 C CB  . GLU A 1 524 ? -55.47238 -31.10128 10.01084  1.000 35.89550  ? 523 GLU A CB  1 
ATOM   3972 C CG  . GLU A 1 524 ? -56.46645 -31.83735 9.11111   1.000 48.03920  ? 523 GLU A CG  1 
ATOM   3973 C CD  . GLU A 1 524 ? -55.80033 -32.78787 8.06619   1.000 57.86617  ? 523 GLU A CD  1 
ATOM   3974 O OE1 . GLU A 1 524 ? -54.75656 -32.40883 7.47347   1.000 50.81652  ? 523 GLU A OE1 1 
ATOM   3975 O OE2 . GLU A 1 524 ? -56.36171 -33.87798 7.77628   1.000 59.35104  ? 523 GLU A OE2 1 
ATOM   3976 N N   . PHE A 1 525 ? -53.85331 -28.22702 10.03234  1.000 38.66279  ? 524 PHE A N   1 
ATOM   3977 C CA  . PHE A 1 525 ? -52.68427 -27.47112 10.48348  1.000 37.83425  ? 524 PHE A CA  1 
ATOM   3978 C C   . PHE A 1 525 ? -53.06770 -26.40365 11.50693  1.000 40.20530  ? 524 PHE A C   1 
ATOM   3979 O O   . PHE A 1 525 ? -52.43927 -26.27340 12.56368  1.000 35.53358  ? 524 PHE A O   1 
ATOM   3980 C CB  . PHE A 1 525 ? -51.99338 -26.82035 9.28736   1.000 28.78855  ? 524 PHE A CB  1 
ATOM   3981 C CG  . PHE A 1 525 ? -50.68696 -26.18219 9.62136   1.000 24.98264  ? 524 PHE A CG  1 
ATOM   3982 C CD1 . PHE A 1 525 ? -50.63985 -24.95176 10.23424  1.000 28.85648  ? 524 PHE A CD1 1 
ATOM   3983 C CD2 . PHE A 1 525 ? -49.50231 -26.81488 9.30859   1.000 28.33130  ? 524 PHE A CD2 1 
ATOM   3984 C CE1 . PHE A 1 525 ? -49.42894 -24.36408 10.55203  1.000 34.14792  ? 524 PHE A CE1 1 
ATOM   3985 C CE2 . PHE A 1 525 ? -48.28734 -26.24172 9.59981   1.000 34.27420  ? 524 PHE A CE2 1 
ATOM   3986 C CZ  . PHE A 1 525 ? -48.24341 -25.00770 10.23141  1.000 35.97605  ? 524 PHE A CZ  1 
ATOM   3987 N N   . TRP A 1 526 ? -54.06679 -25.59470 11.18617  1.000 38.65182  ? 525 TRP A N   1 
ATOM   3988 C CA  . TRP A 1 526 ? -54.32750 -24.44905 12.02713  1.000 33.99965  ? 525 TRP A CA  1 
ATOM   3989 C C   . TRP A 1 526 ? -55.15481 -24.84499 13.22698  1.000 39.96034  ? 525 TRP A C   1 
ATOM   3990 O O   . TRP A 1 526 ? -54.96900 -24.28022 14.31514  1.000 44.37667  ? 525 TRP A O   1 
ATOM   3991 C CB  . TRP A 1 526 ? -54.97710 -23.34663 11.19478  1.000 36.70129  ? 525 TRP A CB  1 
ATOM   3992 C CG  . TRP A 1 526 ? -53.96610 -22.75061 10.24979  1.000 33.92003  ? 525 TRP A CG  1 
ATOM   3993 C CD1 . TRP A 1 526 ? -53.87564 -22.95720 8.90782   1.000 33.49016  ? 525 TRP A CD1 1 
ATOM   3994 C CD2 . TRP A 1 526 ? -52.87140 -21.89626 10.59949  1.000 35.68498  ? 525 TRP A CD2 1 
ATOM   3995 N NE1 . TRP A 1 526 ? -52.79977 -22.27699 8.39374   1.000 36.56223  ? 525 TRP A NE1 1 
ATOM   3996 C CE2 . TRP A 1 526 ? -52.16282 -21.62071 9.41520   1.000 36.15939  ? 525 TRP A CE2 1 
ATOM   3997 C CE3 . TRP A 1 526 ? -52.41582 -21.34680 11.80274  1.000 37.37145  ? 525 TRP A CE3 1 
ATOM   3998 C CZ2 . TRP A 1 526 ? -51.02841 -20.80751 9.39498   1.000 34.87400  ? 525 TRP A CZ2 1 
ATOM   3999 C CZ3 . TRP A 1 526 ? -51.29390 -20.54275 11.78166  1.000 36.46703  ? 525 TRP A CZ3 1 
ATOM   4000 C CH2 . TRP A 1 526 ? -50.60887 -20.28265 10.58368  1.000 38.41369  ? 525 TRP A CH2 1 
ATOM   4001 N N   . ALA A 1 527 ? -56.02502 -25.84437 13.07075  1.000 39.24038  ? 526 ALA A N   1 
ATOM   4002 C CA  . ALA A 1 527 ? -56.68993 -26.40292 14.24203  1.000 38.78382  ? 526 ALA A CA  1 
ATOM   4003 C C   . ALA A 1 527 ? -55.65963 -26.84591 15.27625  1.000 42.66086  ? 526 ALA A C   1 
ATOM   4004 O O   . ALA A 1 527 ? -55.84177 -26.61841 16.47920  1.000 44.54240  ? 526 ALA A O   1 
ATOM   4005 C CB  . ALA A 1 527 ? -57.59868 -27.56318 13.83858  1.000 28.60338  ? 526 ALA A CB  1 
ATOM   4006 N N   . THR A 1 528 ? -54.55130 -27.44981 14.81950  1.000 39.14310  ? 527 THR A N   1 
ATOM   4007 C CA  . THR A 1 528 ? -53.48086 -27.84126 15.73267  1.000 35.41991  ? 527 THR A CA  1 
ATOM   4008 C C   . THR A 1 528 ? -52.86464 -26.61837 16.39912  1.000 36.29483  ? 527 THR A C   1 
ATOM   4009 O O   . THR A 1 528 ? -52.75229 -26.56279 17.62875  1.000 41.13492  ? 527 THR A O   1 
ATOM   4010 C CB  . THR A 1 528 ? -52.41365 -28.65106 14.98830  1.000 36.86052  ? 527 THR A CB  1 
ATOM   4011 O OG1 . THR A 1 528 ? -52.98912 -29.83666 14.44071  1.000 35.23138  ? 527 THR A OG1 1 
ATOM   4012 C CG2 . THR A 1 528 ? -51.29105 -29.05197 15.90894  1.000 35.20589  ? 527 THR A CG2 1 
ATOM   4013 N N   . VAL A 1 529 ? -52.47328 -25.62269 15.59766  1.000 36.46935  ? 528 VAL A N   1 
ATOM   4014 C CA  . VAL A 1 529 ? -51.91111 -24.37877 16.12982  1.000 40.57486  ? 528 VAL A CA  1 
ATOM   4015 C C   . VAL A 1 529 ? -52.85005 -23.77774 17.16782  1.000 39.47684  ? 528 VAL A C   1 
ATOM   4016 O O   . VAL A 1 529 ? -52.42756 -23.38599 18.26363  1.000 35.50435  ? 528 VAL A O   1 
ATOM   4017 C CB  . VAL A 1 529 ? -51.62166 -23.37592 14.99156  1.000 35.81275  ? 528 VAL A CB  1 
ATOM   4018 C CG1 . VAL A 1 529 ? -51.06633 -22.09334 15.54726  1.000 31.94295  ? 528 VAL A CG1 1 
ATOM   4019 C CG2 . VAL A 1 529 ? -50.64337 -23.95178 14.01007  1.000 35.02504  ? 528 VAL A CG2 1 
ATOM   4020 N N   . ALA A 1 530 ? -54.14277 -23.70470 16.83726  1.000 38.57449  ? 529 ALA A N   1 
ATOM   4021 C CA  . ALA A 1 530 ? -55.11429 -23.14650 17.77366  1.000 38.57638  ? 529 ALA A CA  1 
ATOM   4022 C C   . ALA A 1 530 ? -55.10636 -23.91791 19.08884  1.000 41.48904  ? 529 ALA A C   1 
ATOM   4023 O O   . ALA A 1 530 ? -54.98974 -23.32485 20.16474  1.000 42.70509  ? 529 ALA A O   1 
ATOM   4024 C CB  . ALA A 1 530 ? -56.50368 -23.14543 17.14435  1.000 43.21230  ? 529 ALA A CB  1 
ATOM   4025 N N   A HIS A 1 531 ? -55.23457 -25.24834 19.02588  0.480 39.70942  ? 530 HIS A N   1 
ATOM   4026 N N   B HIS A 1 531 ? -55.19568 -25.24730 19.01611  0.520 40.03622  ? 530 HIS A N   1 
ATOM   4027 C CA  A HIS A 1 531 ? -55.10608 -26.04462 20.24145  0.480 39.79560  ? 530 HIS A CA  1 
ATOM   4028 C CA  B HIS A 1 531 ? -55.12071 -26.05269 20.22538  0.520 39.41392  ? 530 HIS A CA  1 
ATOM   4029 C C   A HIS A 1 531 ? -53.77403 -25.77108 20.91870  0.480 41.06002  ? 530 HIS A C   1 
ATOM   4030 C C   B HIS A 1 531 ? -53.76097 -25.91346 20.90146  0.520 41.29400  ? 530 HIS A C   1 
ATOM   4031 O O   A HIS A 1 531 ? -53.70347 -25.66357 22.14790  0.480 41.28356  ? 530 HIS A O   1 
ATOM   4032 O O   B HIS A 1 531 ? -53.65962 -26.05807 22.12459  0.520 41.49532  ? 530 HIS A O   1 
ATOM   4033 C CB  A HIS A 1 531 ? -55.24694 -27.53802 19.92990  0.480 42.52844  ? 530 HIS A CB  1 
ATOM   4034 C CB  B HIS A 1 531 ? -55.41956 -27.51700 19.89295  0.520 42.20759  ? 530 HIS A CB  1 
ATOM   4035 C CG  A HIS A 1 531 ? -55.33057 -28.41601 21.14927  0.480 43.30252  ? 530 HIS A CG  1 
ATOM   4036 C CG  B HIS A 1 531 ? -56.88329 -27.84246 19.82633  0.520 42.88581  ? 530 HIS A CG  1 
ATOM   4037 N ND1 A HIS A 1 531 ? -54.24174 -28.68634 21.95352  0.480 40.80804  ? 530 HIS A ND1 1 
ATOM   4038 N ND1 B HIS A 1 531 ? -57.54163 -28.08051 18.63782  0.520 43.07609  ? 530 HIS A ND1 1 
ATOM   4039 C CD2 A HIS A 1 531 ? -56.36952 -29.10449 21.68307  0.480 43.49222  ? 530 HIS A CD2 1 
ATOM   4040 C CD2 B HIS A 1 531 ? -57.81120 -27.97943 20.80282  0.520 41.53383  ? 530 HIS A CD2 1 
ATOM   4041 C CE1 A HIS A 1 531 ? -54.60993 -29.48827 22.93689  0.480 43.09520  ? 530 HIS A CE1 1 
ATOM   4042 C CE1 B HIS A 1 531 ? -58.81265 -28.34145 18.88490  0.520 45.50062  ? 530 HIS A CE1 1 
ATOM   4043 N NE2 A HIS A 1 531 ? -55.89609 -29.75825 22.79556  0.480 42.71887  ? 530 HIS A NE2 1 
ATOM   4044 N NE2 B HIS A 1 531 ? -59.00157 -28.28830 20.19161  0.520 45.87595  ? 530 HIS A NE2 1 
ATOM   4045 N N   . SER A 1 532 ? -52.70909 -25.62869 20.12728  1.000 43.59583  ? 531 SER A N   1 
ATOM   4046 C CA  . SER A 1 532 ? -51.38282 -25.41914 20.70274  1.000 39.31312  ? 531 SER A CA  1 
ATOM   4047 C C   . SER A 1 532 ? -51.34712 -24.15620 21.54685  1.000 40.16736  ? 531 SER A C   1 
ATOM   4048 O O   . SER A 1 532 ? -50.81953 -24.15947 22.66317  1.000 39.08075  ? 531 SER A O   1 
ATOM   4049 C CB  . SER A 1 532 ? -50.33048 -25.33883 19.59531  1.000 37.28570  ? 531 SER A CB  1 
ATOM   4050 O OG  . SER A 1 532 ? -49.02972 -25.56165 20.10925  1.000 38.46469  ? 531 SER A OG  1 
ATOM   4051 N N   . VAL A 1 533 ? -51.88415 -23.05371 21.01790  1.000 42.46480  ? 532 VAL A N   1 
ATOM   4052 C CA  . VAL A 1 533 ? -51.84163 -21.80037 21.76301  1.000 40.92583  ? 532 VAL A CA  1 
ATOM   4053 C C   . VAL A 1 533 ? -52.70519 -21.91341 23.00437  1.000 42.04579  ? 532 VAL A C   1 
ATOM   4054 O O   . VAL A 1 533 ? -52.34053 -21.42586 24.08297  1.000 38.88676  ? 532 VAL A O   1 
ATOM   4055 C CB  . VAL A 1 533 ? -52.27498 -20.62031 20.87582  1.000 36.78342  ? 532 VAL A CB  1 
ATOM   4056 C CG1 . VAL A 1 533 ? -52.35100 -19.34390 21.68880  1.000 38.37390  ? 532 VAL A CG1 1 
ATOM   4057 C CG2 . VAL A 1 533 ? -51.31793 -20.44724 19.73517  1.000 35.94385  ? 532 VAL A CG2 1 
ATOM   4058 N N   . ALA A 1 534 ? -53.85223 -22.58240 22.87388  1.000 41.60629  ? 533 ALA A N   1 
ATOM   4059 C CA  . ALA A 1 534 ? -54.75074 -22.73678 24.00696  1.000 36.38700  ? 533 ALA A CA  1 
ATOM   4060 C C   . ALA A 1 534 ? -54.09864 -23.55698 25.09718  1.000 39.08679  ? 533 ALA A C   1 
ATOM   4061 O O   . ALA A 1 534 ? -54.23853 -23.25079 26.28704  1.000 47.60081  ? 533 ALA A O   1 
ATOM   4062 C CB  . ALA A 1 534 ? -56.05486 -23.38696 23.56463  1.000 31.78826  ? 533 ALA A CB  1 
ATOM   4063 N N   . GLU A 1 535 ? -53.36860 -24.59721 24.71704  1.000 39.43467  ? 534 GLU A N   1 
ATOM   4064 C CA  . GLU A 1 535 ? -52.73626 -25.41659 25.73741  1.000 40.22162  ? 534 GLU A CA  1 
ATOM   4065 C C   . GLU A 1 535 ? -51.66165 -24.62734 26.47542  1.000 42.01905  ? 534 GLU A C   1 
ATOM   4066 O O   . GLU A 1 535 ? -51.55726 -24.71406 27.69989  1.000 42.36467  ? 534 GLU A O   1 
ATOM   4067 C CB  . GLU A 1 535 ? -52.18523 -26.68382 25.10770  1.000 36.85822  ? 534 GLU A CB  1 
ATOM   4068 C CG  . GLU A 1 535 ? -52.13869 -27.82473 26.05513  1.000 48.08866  ? 534 GLU A CG  1 
ATOM   4069 C CD  . GLU A 1 535 ? -50.83970 -27.82360 26.80490  1.000 48.66105  ? 534 GLU A CD  1 
ATOM   4070 O OE1 . GLU A 1 535 ? -49.82136 -27.44922 26.17664  1.000 49.73218  ? 534 GLU A OE1 1 
ATOM   4071 O OE2 . GLU A 1 535 ? -50.83652 -28.18392 27.99736  1.000 40.65316  ? 534 GLU A OE2 1 
ATOM   4072 N N   . PHE A 1 536 ? -50.89610 -23.80597 25.75801  1.000 42.73375  ? 535 PHE A N   1 
ATOM   4073 C CA  . PHE A 1 536 ? -49.94150 -22.91865 26.41524  1.000 38.06381  ? 535 PHE A CA  1 
ATOM   4074 C C   . PHE A 1 536 ? -50.64355 -21.93868 27.33782  1.000 38.05609  ? 535 PHE A C   1 
ATOM   4075 O O   . PHE A 1 536 ? -50.23028 -21.75204 28.48630  1.000 44.56658  ? 535 PHE A O   1 
ATOM   4076 C CB  . PHE A 1 536 ? -49.11950 -22.15003 25.38133  1.000 39.67167  ? 535 PHE A CB  1 
ATOM   4077 C CG  . PHE A 1 536 ? -48.15979 -21.17713 25.98700  1.000 36.69516  ? 535 PHE A CG  1 
ATOM   4078 C CD1 . PHE A 1 536 ? -46.91587 -21.59676 26.41655  1.000 36.09366  ? 535 PHE A CD1 1 
ATOM   4079 C CD2 . PHE A 1 536 ? -48.50262 -19.84271 26.14046  1.000 37.76139  ? 535 PHE A CD2 1 
ATOM   4080 C CE1 . PHE A 1 536 ? -46.03253 -20.70077 26.99229  1.000 36.81116  ? 535 PHE A CE1 1 
ATOM   4081 C CE2 . PHE A 1 536 ? -47.62124 -18.94363 26.70829  1.000 34.61057  ? 535 PHE A CE2 1 
ATOM   4082 C CZ  . PHE A 1 536 ? -46.38577 -19.37176 27.12880  1.000 35.61339  ? 535 PHE A CZ  1 
ATOM   4083 N N   . GLN A 1 537 ? -51.68223 -21.26278 26.84013  1.000 40.47810  ? 536 GLN A N   1 
ATOM   4084 C CA  . GLN A 1 537 ? -52.39827 -20.30557 27.68225  1.000 42.22730  ? 536 GLN A CA  1 
ATOM   4085 C C   . GLN A 1 537 ? -52.91959 -20.97505 28.95093  1.000 43.46795  ? 536 GLN A C   1 
ATOM   4086 O O   . GLN A 1 537 ? -52.85323 -20.39270 30.04321  1.000 39.95576  ? 536 GLN A O   1 
ATOM   4087 C CB  . GLN A 1 537 ? -53.52858 -19.64562 26.88800  1.000 34.37597  ? 536 GLN A CB  1 
ATOM   4088 C CG  . GLN A 1 537 ? -52.99004 -18.71667 25.81489  1.000 42.21729  ? 536 GLN A CG  1 
ATOM   4089 C CD  . GLN A 1 537 ? -53.99035 -17.67773 25.34171  1.000 47.07937  ? 536 GLN A CD  1 
ATOM   4090 O OE1 . GLN A 1 537 ? -55.19322 -17.80830 25.57005  1.000 43.07400  ? 536 GLN A OE1 1 
ATOM   4091 N NE2 . GLN A 1 537 ? -53.49204 -16.63660 24.66329  1.000 44.92556  ? 536 GLN A NE2 1 
ATOM   4092 N N   . ALA A 1 538 ? -53.39776 -22.21964 28.82567  1.000 40.50336  ? 537 ALA A N   1 
ATOM   4093 C CA  . ALA A 1 538 ? -53.85509 -23.00505 29.96262  1.000 35.62159  ? 537 ALA A CA  1 
ATOM   4094 C C   . ALA A 1 538 ? -52.71346 -23.45647 30.87002  1.000 37.15740  ? 537 ALA A C   1 
ATOM   4095 O O   . ALA A 1 538 ? -52.95860 -23.84108 32.01555  1.000 41.11473  ? 537 ALA A O   1 
ATOM   4096 C CB  . ALA A 1 538 ? -54.62797 -24.22182 29.45892  1.000 36.77658  ? 537 ALA A CB  1 
ATOM   4097 N N   . ARG A 1 539 ? -51.48183 -23.45613 30.38394  1.000 39.74281  ? 538 ARG A N   1 
ATOM   4098 C CA  . ARG A 1 539 ? -50.34792 -23.80166 31.22802  1.000 40.83704  ? 538 ARG A CA  1 
ATOM   4099 C C   . ARG A 1 539 ? -49.83359 -22.60748 32.00377  1.000 40.35374  ? 538 ARG A C   1 
ATOM   4100 O O   . ARG A 1 539 ? -48.92819 -22.77732 32.82749  1.000 37.75340  ? 538 ARG A O   1 
ATOM   4101 C CB  . ARG A 1 539 ? -49.20218 -24.37171 30.38727  1.000 38.09486  ? 538 ARG A CB  1 
ATOM   4102 C CG  . ARG A 1 539 ? -48.36676 -25.42308 31.06723  1.000 40.19858  ? 538 ARG A CG  1 
ATOM   4103 C CD  . ARG A 1 539 ? -47.11626 -25.76062 30.24227  1.000 44.96535  ? 538 ARG A CD  1 
ATOM   4104 N NE  . ARG A 1 539 ? -45.96395 -26.08902 31.07657  1.000 42.31582  ? 538 ARG A NE  1 
ATOM   4105 C CZ  . ARG A 1 539 ? -45.19418 -27.15303 30.91247  1.000 39.48710  ? 538 ARG A CZ  1 
ATOM   4106 N NH1 . ARG A 1 539 ? -45.43083 -28.03411 29.95835  1.000 45.83620  ? 538 ARG A NH1 1 
ATOM   4107 N NH2 . ARG A 1 539 ? -44.15314 -27.33050 31.71980  1.000 43.42777  ? 538 ARG A NH2 1 
ATOM   4108 N N   . HIS A 1 540 ? -50.38122 -21.41566 31.74780  1.000 37.76188  ? 539 HIS A N   1 
ATOM   4109 C CA  . HIS A 1 540 ? -49.82374 -20.16088 32.25574  1.000 38.20358  ? 539 HIS A CA  1 
ATOM   4110 C C   . HIS A 1 540 ? -50.93705 -19.21269 32.67923  1.000 37.51674  ? 539 HIS A C   1 
ATOM   4111 O O   . HIS A 1 540 ? -51.02501 -18.08157 32.19525  1.000 35.53497  ? 539 HIS A O   1 
ATOM   4112 C CB  . HIS A 1 540 ? -48.92553 -19.51854 31.19816  1.000 36.45245  ? 539 HIS A CB  1 
ATOM   4113 C CG  . HIS A 1 540 ? -47.67928 -20.29890 30.91862  1.000 38.92699  ? 539 HIS A CG  1 
ATOM   4114 N ND1 . HIS A 1 540 ? -46.49609 -20.07447 31.58845  1.000 39.13425  ? 539 HIS A ND1 1 
ATOM   4115 C CD2 . HIS A 1 540 ? -47.44558 -21.33930 30.08552  1.000 40.98420  ? 539 HIS A CD2 1 
ATOM   4116 C CE1 . HIS A 1 540 ? -45.57839 -20.91998 31.15500  1.000 36.82203  ? 539 HIS A CE1 1 
ATOM   4117 N NE2 . HIS A 1 540 ? -46.13040 -21.70355 30.24801  1.000 40.90415  ? 539 HIS A NE2 1 
ATOM   4118 N N   . PRO A 1 541 ? -51.79206 -19.63091 33.61822  1.000 39.85449  ? 540 PRO A N   1 
ATOM   4119 C CA  . PRO A 1 541 ? -52.91434 -18.75862 33.98930  1.000 40.51555  ? 540 PRO A CA  1 
ATOM   4120 C C   . PRO A 1 541 ? -52.45819 -17.44184 34.58529  1.000 42.65334  ? 540 PRO A C   1 
ATOM   4121 O O   . PRO A 1 541 ? -53.14761 -16.42871 34.41623  1.000 45.81762  ? 540 PRO A O   1 
ATOM   4122 C CB  . PRO A 1 541 ? -53.71403 -19.60528 34.98908  1.000 33.19251  ? 540 PRO A CB  1 
ATOM   4123 C CG  . PRO A 1 541 ? -52.73614 -20.55440 35.55590  1.000 33.98123  ? 540 PRO A CG  1 
ATOM   4124 C CD  . PRO A 1 541 ? -51.71989 -20.82399 34.47789  1.000 41.36766  ? 540 PRO A CD  1 
ATOM   4125 N N   . ASP A 1 542 ? -51.28568 -17.40137 35.21826  1.000 38.90907  ? 541 ASP A N   1 
ATOM   4126 C CA  . ASP A 1 542 ? -50.82798 -16.14300 35.78806  1.000 41.01474  ? 541 ASP A CA  1 
ATOM   4127 C C   . ASP A 1 542 ? -50.55755 -15.06650 34.72967  1.000 45.25459  ? 541 ASP A C   1 
ATOM   4128 O O   . ASP A 1 542 ? -50.44522 -13.88792 35.09293  1.000 46.25010  ? 541 ASP A O   1 
ATOM   4129 C CB  . ASP A 1 542 ? -49.58382 -16.39684 36.64156  1.000 49.29595  ? 541 ASP A CB  1 
ATOM   4130 C CG  . ASP A 1 542 ? -49.88445 -17.22241 37.90951  1.000 53.00362  ? 541 ASP A CG  1 
ATOM   4131 O OD1 . ASP A 1 542 ? -51.04915 -17.23774 38.38191  1.000 51.49777  ? 541 ASP A OD1 1 
ATOM   4132 O OD2 . ASP A 1 542 ? -48.94389 -17.86466 38.42911  1.000 49.15138  ? 541 ASP A OD2 1 
ATOM   4133 N N   . LEU A 1 543 ? -50.48430 -15.42105 33.43949  1.000 37.46534  ? 542 LEU A N   1 
ATOM   4134 C CA  . LEU A 1 543 ? -50.33724 -14.43411 32.37569  1.000 39.01009  ? 542 LEU A CA  1 
ATOM   4135 C C   . LEU A 1 543 ? -51.65467 -14.10921 31.66771  1.000 43.80657  ? 542 LEU A C   1 
ATOM   4136 O O   . LEU A 1 543 ? -51.64267 -13.41231 30.64394  1.000 40.06213  ? 542 LEU A O   1 
ATOM   4137 C CB  . LEU A 1 543 ? -49.30963 -14.90106 31.34944  1.000 38.38828  ? 542 LEU A CB  1 
ATOM   4138 C CG  . LEU A 1 543 ? -47.91275 -15.29931 31.81334  1.000 38.05291  ? 542 LEU A CG  1 
ATOM   4139 C CD1 . LEU A 1 543 ? -47.34208 -16.31891 30.85160  1.000 38.52331  ? 542 LEU A CD1 1 
ATOM   4140 C CD2 . LEU A 1 543 ? -46.99510 -14.10365 31.89918  1.000 38.40323  ? 542 LEU A CD2 1 
ATOM   4141 N N   . ALA A 1 544 ? -52.78856 -14.57213 32.20377  1.000 41.62603  ? 543 ALA A N   1 
ATOM   4142 C CA  . ALA A 1 544 ? -54.07768 -14.34351 31.55538  1.000 38.65807  ? 543 ALA A CA  1 
ATOM   4143 C C   . ALA A 1 544 ? -54.35028 -12.86677 31.29440  1.000 45.36093  ? 543 ALA A C   1 
ATOM   4144 O O   . ALA A 1 544 ? -55.01839 -12.52702 30.31543  1.000 55.06110  ? 543 ALA A O   1 
ATOM   4145 C CB  . ALA A 1 544 ? -55.19739 -14.92876 32.40790  1.000 35.00014  ? 543 ALA A CB  1 
ATOM   4146 N N   . ASP A 1 545 ? -53.87636 -11.97670 32.16504  1.000 52.56463  ? 544 ASP A N   1 
ATOM   4147 C CA  . ASP A 1 545 ? -54.10713 -10.55031 31.96458  1.000 47.39047  ? 544 ASP A CA  1 
ATOM   4148 C C   . ASP A 1 545 ? -53.43523 -10.08628 30.68695  1.000 56.62259  ? 544 ASP A C   1 
ATOM   4149 O O   . ASP A 1 545 ? -54.03026 -9.37149  29.87021  1.000 55.73820  ? 544 ASP A O   1 
ATOM   4150 C CB  . ASP A 1 545 ? -53.56897 -9.77216  33.15762  1.000 54.48131  ? 544 ASP A CB  1 
ATOM   4151 C CG  . ASP A 1 545 ? -54.65380 -9.41964  34.15840  1.000 77.74130  ? 544 ASP A CG  1 
ATOM   4152 O OD1 . ASP A 1 545 ? -55.85720 -9.55791  33.82648  1.000 75.67496  ? 544 ASP A OD1 1 
ATOM   4153 O OD2 . ASP A 1 545 ? -54.29567 -9.01762  35.28949  1.000 82.33062  ? 544 ASP A OD2 1 
ATOM   4154 N N   . ARG A 1 546 ? -52.18757 -10.51282 30.49197  1.000 54.71816  ? 545 ARG A N   1 
ATOM   4155 C CA  . ARG A 1 546 ? -51.46683 -10.17077 29.28128  1.000 45.75187  ? 545 ARG A CA  1 
ATOM   4156 C C   . ARG A 1 546 ? -52.10750 -10.81499 28.06121  1.000 51.70778  ? 545 ARG A C   1 
ATOM   4157 O O   . ARG A 1 546 ? -52.20387 -10.17858 27.00108  1.000 54.82424  ? 545 ARG A O   1 
ATOM   4158 C CB  . ARG A 1 546 ? -50.01449 -10.59120 29.42419  1.000 46.54887  ? 545 ARG A CB  1 
ATOM   4159 C CG  . ARG A 1 546 ? -49.48108 -10.46141 30.81890  1.000 42.90845  ? 545 ARG A CG  1 
ATOM   4160 C CD  . ARG A 1 546 ? -48.03802 -9.98305  30.81362  1.000 44.29441  ? 545 ARG A CD  1 
ATOM   4161 N NE  . ARG A 1 546 ? -47.40445 -10.19071 32.11228  1.000 54.03981  ? 545 ARG A NE  1 
ATOM   4162 C CZ  . ARG A 1 546 ? -46.17768 -9.80069  32.43351  1.000 51.79195  ? 545 ARG A CZ  1 
ATOM   4163 N NH1 . ARG A 1 546 ? -45.40704 -9.15894  31.57045  1.000 61.31257  ? 545 ARG A NH1 1 
ATOM   4164 N NH2 . ARG A 1 546 ? -45.71148 -10.06379 33.65118  1.000 47.73503  ? 545 ARG A NH2 1 
ATOM   4165 N N   . PHE A 1 547 ? -52.55889 -12.07391 28.18848  1.000 49.28380  ? 546 PHE A N   1 
ATOM   4166 C CA  . PHE A 1 547 ? -53.24809 -12.72504 27.07316  1.000 43.99749  ? 546 PHE A CA  1 
ATOM   4167 C C   . PHE A 1 547 ? -54.45408 -11.91823 26.62809  1.000 48.52444  ? 546 PHE A C   1 
ATOM   4168 O O   . PHE A 1 547 ? -54.77791 -11.89880 25.43583  1.000 50.54754  ? 546 PHE A O   1 
ATOM   4169 C CB  . PHE A 1 547 ? -53.67628 -14.14508 27.43933  1.000 40.46083  ? 546 PHE A CB  1 
ATOM   4170 C CG  . PHE A 1 547 ? -52.52032 -15.09050 27.68532  1.000 45.51923  ? 546 PHE A CG  1 
ATOM   4171 C CD1 . PHE A 1 547 ? -51.41322 -15.09277 26.85211  1.000 47.29495  ? 546 PHE A CD1 1 
ATOM   4172 C CD2 . PHE A 1 547 ? -52.54032 -15.96643 28.75766  1.000 37.87573  ? 546 PHE A CD2 1 
ATOM   4173 C CE1 . PHE A 1 547 ? -50.35971 -15.94680 27.09412  1.000 46.26011  ? 546 PHE A CE1 1 
ATOM   4174 C CE2 . PHE A 1 547 ? -51.49327 -16.81125 28.99616  1.000 36.75293  ? 546 PHE A CE2 1 
ATOM   4175 C CZ  . PHE A 1 547 ? -50.40175 -16.80361 28.17560  1.000 40.30925  ? 546 PHE A CZ  1 
ATOM   4176 N N   . ASP A 1 548 ? -55.10884 -11.21755 27.55671  1.000 49.36409  ? 547 ASP A N   1 
ATOM   4177 C CA  . ASP A 1 548 ? -56.20039 -10.33899 27.15348  1.000 55.39055  ? 547 ASP A CA  1 
ATOM   4178 C C   . ASP A 1 548 ? -55.67347 -9.03009  26.59129  1.000 52.11338  ? 547 ASP A C   1 
ATOM   4179 O O   . ASP A 1 548 ? -56.23470 -8.48429  25.63678  1.000 48.54533  ? 547 ASP A O   1 
ATOM   4180 C CB  . ASP A 1 548 ? -57.13056 -10.06359 28.32939  1.000 54.10533  ? 547 ASP A CB  1 
ATOM   4181 C CG  . ASP A 1 548 ? -58.13696 -11.17875 28.55326  1.000 66.56666  ? 547 ASP A CG  1 
ATOM   4182 O OD1 . ASP A 1 548 ? -58.08716 -12.20803 27.83590  1.000 69.18304  ? 547 ASP A OD1 1 
ATOM   4183 O OD2 . ASP A 1 548 ? -58.99803 -11.01227 29.44258  1.000 72.93785  ? 547 ASP A OD2 1 
ATOM   4184 N N   . GLN A 1 549 ? -54.60550 -8.50491  27.18059  1.000 53.35095  ? 548 GLN A N   1 
ATOM   4185 C CA  . GLN A 1 549 ? -53.99217 -7.30229  26.64025  1.000 51.25400  ? 548 GLN A CA  1 
ATOM   4186 C C   . GLN A 1 549 ? -53.65638 -7.49228  25.16749  1.000 51.43514  ? 548 GLN A C   1 
ATOM   4187 O O   . GLN A 1 549 ? -54.14769 -6.76141  24.30358  1.000 52.82454  ? 548 GLN A O   1 
ATOM   4188 C CB  . GLN A 1 549 ? -52.74002 -6.95868  27.44894  1.000 51.00992  ? 548 GLN A CB  1 
ATOM   4189 C CG  . GLN A 1 549 ? -52.62958 -5.50953  27.85191  1.000 53.40180  ? 548 GLN A CG  1 
ATOM   4190 C CD  . GLN A 1 549 ? -51.39391 -5.22154  28.69784  1.000 60.01812  ? 548 GLN A CD  1 
ATOM   4191 O OE1 . GLN A 1 549 ? -50.90674 -6.09494  29.43093  1.000 58.38426  ? 548 GLN A OE1 1 
ATOM   4192 N NE2 . GLN A 1 549 ? -50.89048 -3.98540  28.61315  1.000 56.53772  ? 548 GLN A NE2 1 
ATOM   4193 N N   . TRP A 1 550 ? -52.85854 -8.51240  24.86458  1.000 49.96617  ? 549 TRP A N   1 
ATOM   4194 C CA  . TRP A 1 550 ? -52.22303 -8.68717  23.56053  1.000 48.70097  ? 549 TRP A CA  1 
ATOM   4195 C C   . TRP A 1 550 ? -52.82665 -9.92121  22.89807  1.000 47.05389  ? 549 TRP A C   1 
ATOM   4196 O O   . TRP A 1 550 ? -52.30313 -11.02871 23.03131  1.000 45.05911  ? 549 TRP A O   1 
ATOM   4197 C CB  . TRP A 1 550 ? -50.72978 -8.81711  23.74649  1.000 47.35983  ? 549 TRP A CB  1 
ATOM   4198 C CG  . TRP A 1 550 ? -50.12307 -7.69926  24.56377  1.000 47.70020  ? 549 TRP A CG  1 
ATOM   4199 C CD1 . TRP A 1 550 ? -50.31782 -6.36128  24.39337  1.000 51.34865  ? 549 TRP A CD1 1 
ATOM   4200 C CD2 . TRP A 1 550 ? -49.20969 -7.82985  25.66013  1.000 52.12073  ? 549 TRP A CD2 1 
ATOM   4201 N NE1 . TRP A 1 550 ? -49.58553 -5.64856  25.31325  1.000 47.93679  ? 549 TRP A NE1 1 
ATOM   4202 C CE2 . TRP A 1 550 ? -48.89400 -6.52759  26.10029  1.000 51.64439  ? 549 TRP A CE2 1 
ATOM   4203 C CE3 . TRP A 1 550 ? -48.62019 -8.92291  26.30970  1.000 51.93157  ? 549 TRP A CE3 1 
ATOM   4204 C CZ2 . TRP A 1 550 ? -48.01918 -6.28940  27.15660  1.000 53.04637  ? 549 TRP A CZ2 1 
ATOM   4205 C CZ3 . TRP A 1 550 ? -47.75068 -8.68340  27.35727  1.000 50.15561  ? 549 TRP A CZ3 1 
ATOM   4206 C CH2 . TRP A 1 550 ? -47.46094 -7.37643  27.77245  1.000 52.62341  ? 549 TRP A CH2 1 
ATOM   4207 N N   . ASP A 1 551 ? -53.92668 -9.71735  22.16987  1.000 41.52010  ? 550 ASP A N   1 
ATOM   4208 C CA  . ASP A 1 551 ? -54.87060 -10.79925 21.88217  1.000 40.41184  ? 550 ASP A CA  1 
ATOM   4209 C C   . ASP A 1 551 ? -54.31541 -11.70759 20.80202  1.000 40.65561  ? 550 ASP A C   1 
ATOM   4210 O O   . ASP A 1 551 ? -54.33227 -11.37342 19.61675  1.000 47.66602  ? 550 ASP A O   1 
ATOM   4211 C CB  . ASP A 1 551 ? -56.23289 -10.24810 21.47672  1.000 43.32057  ? 550 ASP A CB  1 
ATOM   4212 C CG  . ASP A 1 551 ? -57.33776 -11.30271 21.55678  1.000 44.51927  ? 550 ASP A CG  1 
ATOM   4213 O OD1 . ASP A 1 551 ? -57.06025 -12.42533 22.03462  1.000 44.45467  ? 550 ASP A OD1 1 
ATOM   4214 O OD2 . ASP A 1 551 ? -58.48534 -11.01391 21.13839  1.000 44.03050  ? 550 ASP A OD2 1 
ATOM   4215 N N   . LEU A 1 552 ? -53.85542 -12.88479 21.20852  1.000 40.77355  ? 551 LEU A N   1 
ATOM   4216 C CA  . LEU A 1 552 ? -53.35923 -13.84751 20.24180  1.000 34.59055  ? 551 LEU A CA  1 
ATOM   4217 C C   . LEU A 1 552 ? -54.48946 -14.43207 19.39670  1.000 39.85700  ? 551 LEU A C   1 
ATOM   4218 O O   . LEU A 1 552 ? -54.22835 -14.92208 18.29285  1.000 43.93313  ? 551 LEU A O   1 
ATOM   4219 C CB  . LEU A 1 552 ? -52.59424 -14.93958 20.98741  1.000 35.72900  ? 551 LEU A CB  1 
ATOM   4220 C CG  . LEU A 1 552 ? -51.08226 -14.70661 21.11488  1.000 38.18147  ? 551 LEU A CG  1 
ATOM   4221 C CD1 . LEU A 1 552 ? -50.37980 -15.86844 21.80859  1.000 31.34598  ? 551 LEU A CD1 1 
ATOM   4222 C CD2 . LEU A 1 552 ? -50.46100 -14.44819 19.74839  1.000 47.23070  ? 551 LEU A CD2 1 
ATOM   4223 N N   . PHE A 1 553 ? -55.74116 -14.36896 19.87109  1.000 40.39520  ? 552 PHE A N   1 
ATOM   4224 C CA  . PHE A 1 553 ? -56.90510 -14.81860 19.10873  1.000 39.94304  ? 552 PHE A CA  1 
ATOM   4225 C C   . PHE A 1 553 ? -57.68206 -13.65982 18.50667  1.000 38.18749  ? 552 PHE A C   1 
ATOM   4226 O O   . PHE A 1 553 ? -58.89569 -13.77053 18.28759  1.000 36.92047  ? 552 PHE A O   1 
ATOM   4227 C CB  . PHE A 1 553 ? -57.83882 -15.66426 19.96924  1.000 39.56370  ? 552 PHE A CB  1 
ATOM   4228 C CG  . PHE A 1 553 ? -57.28486 -16.99553 20.31536  1.000 41.87755  ? 552 PHE A CG  1 
ATOM   4229 C CD1 . PHE A 1 553 ? -56.42661 -17.13832 21.39309  1.000 42.01991  ? 552 PHE A CD1 1 
ATOM   4230 C CD2 . PHE A 1 553 ? -57.60291 -18.10589 19.56260  1.000 44.44653  ? 552 PHE A CD2 1 
ATOM   4231 C CE1 . PHE A 1 553 ? -55.89325 -18.37582 21.71893  1.000 42.37807  ? 552 PHE A CE1 1 
ATOM   4232 C CE2 . PHE A 1 553 ? -57.08051 -19.34604 19.88274  1.000 43.30573  ? 552 PHE A CE2 1 
ATOM   4233 C CZ  . PHE A 1 553 ? -56.22753 -19.48116 20.96279  1.000 41.73537  ? 552 PHE A CZ  1 
ATOM   4234 N N   . ALA A 1 554 ? -57.00607 -12.54500 18.25201  1.000 38.26239  ? 553 ALA A N   1 
ATOM   4235 C CA  . ALA A 1 554 ? -57.58347 -11.43387 17.51213  1.000 36.76032  ? 553 ALA A CA  1 
ATOM   4236 C C   . ALA A 1 554 ? -58.11443 -11.94983 16.18312  1.000 38.47518  ? 553 ALA A C   1 
ATOM   4237 O O   . ALA A 1 554 ? -57.61245 -12.96026 15.67595  1.000 42.95707  ? 553 ALA A O   1 
ATOM   4238 C CB  . ALA A 1 554 ? -56.54149 -10.33952 17.29061  1.000 38.36394  ? 553 ALA A CB  1 
ATOM   4239 N N   . PRO A 1 555 ? -59.12817 -11.31238 15.59220  1.000 41.46116  ? 554 PRO A N   1 
ATOM   4240 C CA  . PRO A 1 555 ? -59.69712 -11.84157 14.34011  1.000 37.35597  ? 554 PRO A CA  1 
ATOM   4241 C C   . PRO A 1 555 ? -58.89668 -11.45602 13.11139  1.000 34.62945  ? 554 PRO A C   1 
ATOM   4242 O O   . PRO A 1 555 ? -58.79412 -12.24914 12.17803  1.000 40.12177  ? 554 PRO A O   1 
ATOM   4243 C CB  . PRO A 1 555 ? -61.10557 -11.22957 14.30180  1.000 40.10053  ? 554 PRO A CB  1 
ATOM   4244 C CG  . PRO A 1 555 ? -61.33641 -10.63990 15.67139  1.000 34.26182  ? 554 PRO A CG  1 
ATOM   4245 C CD  . PRO A 1 555 ? -59.97104 -10.25180 16.15778  1.000 38.49407  ? 554 PRO A CD  1 
ATOM   4246 N N   . THR A 1 556 ? -58.33596 -10.24979 13.08633  1.000 36.75027  ? 555 THR A N   1 
ATOM   4247 C CA  . THR A 1 556 ? -57.42041 -9.84067  12.03139  1.000 39.36693  ? 555 THR A CA  1 
ATOM   4248 C C   . THR A 1 556 ? -56.19330 -9.16939  12.62589  1.000 40.52215  ? 555 THR A C   1 
ATOM   4249 O O   . THR A 1 556 ? -56.21417 -8.65044  13.74522  1.000 44.47014  ? 555 THR A O   1 
ATOM   4250 C CB  . THR A 1 556 ? -58.04884 -8.85038  11.04899  1.000 40.89887  ? 555 THR A CB  1 
ATOM   4251 O OG1 . THR A 1 556 ? -58.14565 -7.56059  11.67910  1.000 37.85979  ? 555 THR A OG1 1 
ATOM   4252 C CG2 . THR A 1 556 ? -59.41126 -9.31909  10.60863  1.000 33.37047  ? 555 THR A CG2 1 
ATOM   4253 N N   . PHE A 1 557 ? -55.12622 -9.16319  11.84610  1.000 40.31645  ? 556 PHE A N   1 
ATOM   4254 C CA  . PHE A 1 557 ? -53.96315 -8.34071  12.12449  1.000 41.86634  ? 556 PHE A CA  1 
ATOM   4255 C C   . PHE A 1 557 ? -53.47512 -7.82368  10.78766  1.000 42.18695  ? 556 PHE A C   1 
ATOM   4256 O O   . PHE A 1 557 ? -53.87388 -8.34647  9.73987   1.000 40.58500  ? 556 PHE A O   1 
ATOM   4257 C CB  . PHE A 1 557 ? -52.85600 -9.11146  12.86286  1.000 40.76520  ? 556 PHE A CB  1 
ATOM   4258 C CG  . PHE A 1 557 ? -52.30373 -10.26853 12.10058  1.000 44.74367  ? 556 PHE A CG  1 
ATOM   4259 C CD1 . PHE A 1 557 ? -52.97104 -11.48610 12.08475  1.000 41.25659  ? 556 PHE A CD1 1 
ATOM   4260 C CD2 . PHE A 1 557 ? -51.10704 -10.14845 11.40726  1.000 45.10776  ? 556 PHE A CD2 1 
ATOM   4261 C CE1 . PHE A 1 557 ? -52.45578 -12.54749 11.39586  1.000 41.14685  ? 556 PHE A CE1 1 
ATOM   4262 C CE2 . PHE A 1 557 ? -50.58629 -11.21045 10.70717  1.000 41.30296  ? 556 PHE A CE2 1 
ATOM   4263 C CZ  . PHE A 1 557 ? -51.25747 -12.40961 10.69978  1.000 43.39948  ? 556 PHE A CZ  1 
ATOM   4264 N N   . PRO A 1 558 ? -52.64515 -6.77866  10.78248  1.000 41.24970  ? 557 PRO A N   1 
ATOM   4265 C CA  . PRO A 1 558 ? -52.19995 -6.19602  9.51354   1.000 43.63202  ? 557 PRO A CA  1 
ATOM   4266 C C   . PRO A 1 558 ? -51.03582 -6.95288  8.90368   1.000 43.06724  ? 557 PRO A C   1 
ATOM   4267 O O   . PRO A 1 558 ? -50.17075 -7.49468  9.60146   1.000 43.67628  ? 557 PRO A O   1 
ATOM   4268 C CB  . PRO A 1 558 ? -51.77681 -4.77747  9.90912   1.000 41.87818  ? 557 PRO A CB  1 
ATOM   4269 C CG  . PRO A 1 558 ? -51.31011 -4.92250  11.27226  1.000 41.48987  ? 557 PRO A CG  1 
ATOM   4270 C CD  . PRO A 1 558 ? -52.19075 -5.97095  11.92191  1.000 35.22080  ? 557 PRO A CD  1 
ATOM   4271 N N   . ALA A 1 559 ? -51.03561 -6.98522  7.57256   1.000 45.30709  ? 558 ALA A N   1 
ATOM   4272 C CA  . ALA A 1 559 ? -49.95157 -7.61250  6.83165   1.000 45.94584  ? 558 ALA A CA  1 
ATOM   4273 C C   . ALA A 1 559 ? -48.71300 -6.72737  6.87259   1.000 44.11686  ? 558 ALA A C   1 
ATOM   4274 O O   . ALA A 1 559 ? -48.80733 -5.50691  7.01159   1.000 46.96199  ? 558 ALA A O   1 
ATOM   4275 C CB  . ALA A 1 559 ? -50.37435 -7.85600  5.38373   1.000 40.75282  ? 558 ALA A CB  1 
ATOM   4276 N N   . ILE A 1 560 ? -47.54156 -7.34622  6.76776   1.000 38.18766  ? 559 ILE A N   1 
ATOM   4277 C CA  . ILE A 1 560 ? -46.30483 -6.61189  6.49882   1.000 44.65630  ? 559 ILE A CA  1 
ATOM   4278 C C   . ILE A 1 560 ? -45.67573 -7.24551  5.26599   1.000 48.81257  ? 559 ILE A C   1 
ATOM   4279 O O   . ILE A 1 560 ? -45.03055 -8.29459  5.36188   1.000 57.68036  ? 559 ILE A O   1 
ATOM   4280 C CB  . ILE A 1 560 ? -45.33260 -6.61782  7.68184   1.000 42.57370  ? 559 ILE A CB  1 
ATOM   4281 C CG1 . ILE A 1 560 ? -45.93006 -5.86743  8.87138   1.000 43.61820  ? 559 ILE A CG1 1 
ATOM   4282 C CG2 . ILE A 1 560 ? -44.01694 -5.97127  7.27801   1.000 36.94122  ? 559 ILE A CG2 1 
ATOM   4283 C CD1 . ILE A 1 560 ? -45.34847 -6.27063  10.19099  1.000 32.29768  ? 559 ILE A CD1 1 
ATOM   4284 N N   . HIS A 1 561 ? -45.84138 -6.60205  4.11181   1.000 46.83320  ? 560 HIS A N   1 
ATOM   4285 C CA  . HIS A 1 561 ? -45.38534 -7.13246  2.82727   1.000 49.68048  ? 560 HIS A CA  1 
ATOM   4286 C C   . HIS A 1 561 ? -43.86860 -7.06760  2.73132   1.000 51.81344  ? 560 HIS A C   1 
ATOM   4287 O O   . HIS A 1 561 ? -43.28600 -6.02171  2.42975   1.000 44.17514  ? 560 HIS A O   1 
ATOM   4288 C CB  . HIS A 1 561 ? -46.04891 -6.36134  1.70209   1.000 47.51981  ? 560 HIS A CB  1 
ATOM   4289 C CG  . HIS A 1 561 ? -47.53363 -6.40793  1.77912   1.000 51.30060  ? 560 HIS A CG  1 
ATOM   4290 N ND1 . HIS A 1 561 ? -48.34690 -5.45987  1.19877   1.000 50.47389  ? 560 HIS A ND1 1 
ATOM   4291 C CD2 . HIS A 1 561 ? -48.35513 -7.28952  2.39680   1.000 50.89521  ? 560 HIS A CD2 1 
ATOM   4292 C CE1 . HIS A 1 561 ? -49.60882 -5.76099  1.44869   1.000 55.54386  ? 560 HIS A CE1 1 
ATOM   4293 N NE2 . HIS A 1 561 ? -49.64077 -6.86780  2.17062   1.000 57.77749  ? 560 HIS A NE2 1 
ATOM   4294 N N   . MET A 1 562 ? -43.23680 -8.21753  2.97437   1.000 54.67313  ? 561 MET A N   1 
ATOM   4295 C CA  . MET A 1 562 ? -41.78304 -8.32066  2.94464   1.000 53.60834  ? 561 MET A CA  1 
ATOM   4296 C C   . MET A 1 562 ? -41.20635 -7.77263  1.63949   1.000 58.20112  ? 561 MET A C   1 
ATOM   4297 O O   . MET A 1 562 ? -40.33924 -6.88881  1.65788   1.000 57.62420  ? 561 MET A O   1 
ATOM   4298 C CB  . MET A 1 562 ? -41.37956 -9.78649  3.12459   1.000 62.25824  ? 561 MET A CB  1 
ATOM   4299 C CG  . MET A 1 562 ? -41.42115 -10.35169 4.54615   1.000 61.91469  ? 561 MET A CG  1 
ATOM   4300 S SD  . MET A 1 562 ? -40.76012 -9.33565  5.86856   1.000 65.44490  ? 561 MET A SD  1 
ATOM   4301 C CE  . MET A 1 562 ? -39.24138 -8.69362  5.14464   1.000 66.63226  ? 561 MET A CE  1 
ATOM   4302 N N   . ASN A 1 563 ? -41.69077 -8.29000  0.48873   1.000 57.37434  ? 562 ASN A N   1 
ATOM   4303 C CA  . ASN A 1 563 ? -41.10146 -7.99343  -0.82088  1.000 47.02699  ? 562 ASN A CA  1 
ATOM   4304 C C   . ASN A 1 563 ? -41.31952 -6.54544  -1.24492  1.000 50.59885  ? 562 ASN A C   1 
ATOM   4305 O O   . ASN A 1 563 ? -40.51216 -5.99993  -1.99701  1.000 56.91411  ? 562 ASN A O   1 
ATOM   4306 C CB  . ASN A 1 563 ? -41.66522 -8.93746  -1.88735  1.000 40.43800  ? 562 ASN A CB  1 
ATOM   4307 C CG  . ASN A 1 563 ? -40.93334 -10.26697 -1.94249  1.000 43.28436  ? 562 ASN A CG  1 
ATOM   4308 O OD1 . ASN A 1 563 ? -39.79531 -10.35637 -2.39832  1.000 46.90553  ? 562 ASN A OD1 1 
ATOM   4309 N ND2 . ASN A 1 563 ? -41.58326 -11.30670 -1.46408  1.000 47.39988  ? 562 ASN A ND2 1 
ATOM   4310 N N   . ARG A 1 564 ? -42.39498 -5.90604  -0.79221  1.000 55.69285  ? 563 ARG A N   1 
ATOM   4311 C CA  . ARG A 1 564 ? -42.55396 -4.47593  -1.03597  1.000 53.77259  ? 563 ARG A CA  1 
ATOM   4312 C C   . ARG A 1 564 ? -41.40876 -3.67355  -0.41054  1.000 58.29809  ? 563 ARG A C   1 
ATOM   4313 O O   . ARG A 1 564 ? -40.78340 -2.84627  -1.08548  1.000 62.08295  ? 563 ARG A O   1 
ATOM   4314 C CB  . ARG A 1 564 ? -43.90202 -4.00228  -0.49772  1.000 52.20911  ? 563 ARG A CB  1 
ATOM   4315 C CG  . ARG A 1 564 ? -45.07797 -4.43645  -1.33360  1.000 47.67895  ? 563 ARG A CG  1 
ATOM   4316 C CD  . ARG A 1 564 ? -46.35336 -3.72727  -0.88883  1.000 49.21242  ? 563 ARG A CD  1 
ATOM   4317 N NE  . ARG A 1 564 ? -47.01341 -3.12146  -2.03529  1.000 50.25953  ? 563 ARG A NE  1 
ATOM   4318 C CZ  . ARG A 1 564 ? -48.02891 -3.66366  -2.68956  1.000 54.06061  ? 563 ARG A CZ  1 
ATOM   4319 N NH1 . ARG A 1 564 ? -48.62325 -4.76048  -2.24777  1.000 54.27016  ? 563 ARG A NH1 1 
ATOM   4320 N NH2 . ARG A 1 564 ? -48.45168 -3.09629  -3.82152  1.000 53.36204  ? 563 ARG A NH2 1 
ATOM   4321 N N   . LEU A 1 565 ? -41.12367 -3.89106  0.88160   1.000 49.86296  ? 564 LEU A N   1 
ATOM   4322 C CA  . LEU A 1 565 ? -40.01574 -3.17445  1.52115   1.000 58.90358  ? 564 LEU A CA  1 
ATOM   4323 C C   . LEU A 1 565 ? -38.73850 -3.27923  0.69161   1.000 64.32030  ? 564 LEU A C   1 
ATOM   4324 O O   . LEU A 1 565 ? -38.10372 -2.26595  0.37631   1.000 70.59211  ? 564 LEU A O   1 
ATOM   4325 C CB  . LEU A 1 565 ? -39.75752 -3.70174  2.93860   1.000 62.00311  ? 564 LEU A CB  1 
ATOM   4326 C CG  . LEU A 1 565 ? -40.89585 -3.94623  3.93004   1.000 59.03332  ? 564 LEU A CG  1 
ATOM   4327 C CD1 . LEU A 1 565 ? -40.36773 -4.63877  5.17639   1.000 60.41723  ? 564 LEU A CD1 1 
ATOM   4328 C CD2 . LEU A 1 565 ? -41.56702 -2.64321  4.29278   1.000 50.47404  ? 564 LEU A CD2 1 
ATOM   4329 N N   . GLN A 1 566 ? -38.35223 -4.50534  0.32297   1.000 59.39878  ? 565 GLN A N   1 
ATOM   4330 C CA  . GLN A 1 566 ? -37.17177 -4.68968  -0.51299  1.000 59.86834  ? 565 GLN A CA  1 
ATOM   4331 C C   . GLN A 1 566 ? -37.31905 -3.95883  -1.85177  1.000 66.74952  ? 565 GLN A C   1 
ATOM   4332 O O   . GLN A 1 566 ? -36.37216 -3.31671  -2.31969  1.000 74.79396  ? 565 GLN A O   1 
ATOM   4333 C CB  . GLN A 1 566 ? -36.88974 -6.18739  -0.72061  1.000 58.49467  ? 565 GLN A CB  1 
ATOM   4334 C CG  . GLN A 1 566 ? -35.83927 -6.46591  -1.83269  1.000 67.36030  ? 565 GLN A CG  1 
ATOM   4335 C CD  . GLN A 1 566 ? -35.39331 -7.93641  -1.98327  1.000 63.60139  ? 565 GLN A CD  1 
ATOM   4336 O OE1 . GLN A 1 566 ? -36.21998 -8.86521  -2.02174  1.000 62.20901  ? 565 GLN A OE1 1 
ATOM   4337 N NE2 . GLN A 1 566 ? -34.06880 -8.14025  -2.10117  1.000 47.76547  ? 565 GLN A NE2 1 
ATOM   4338 N N   . LEU A 1 567 ? -38.50135 -4.01120  -2.47122  1.000 64.02053  ? 566 LEU A N   1 
ATOM   4339 C CA  . LEU A 1 567 ? -38.71838 -3.31466  -3.73974  1.000 62.45967  ? 566 LEU A CA  1 
ATOM   4340 C C   . LEU A 1 567 ? -38.95012 -1.81872  -3.52362  1.000 71.75985  ? 566 LEU A C   1 
ATOM   4341 O O   . LEU A 1 567 ? -39.90184 -1.24878  -4.07307  1.000 71.76923  ? 566 LEU A O   1 
ATOM   4342 C CB  . LEU A 1 567 ? -39.91015 -3.91892  -4.48780  1.000 53.39387  ? 566 LEU A CB  1 
ATOM   4343 C CG  . LEU A 1 567 ? -39.76005 -5.32121  -5.05804  1.000 46.92433  ? 566 LEU A CG  1 
ATOM   4344 C CD1 . LEU A 1 567 ? -41.10716 -5.89004  -5.47466  1.000 47.59456  ? 566 LEU A CD1 1 
ATOM   4345 C CD2 . LEU A 1 567 ? -38.81096 -5.30953  -6.23204  1.000 54.98735  ? 566 LEU A CD2 1 
ATOM   4346 N N   . SER A 1 568 ? -38.09267 -1.17379  -2.73095  1.000 73.01884  ? 567 SER A N   1 
ATOM   4347 C CA  . SER A 1 568 ? -38.22936 0.25390   -2.44043  1.000 73.78910  ? 567 SER A CA  1 
ATOM   4348 C C   . SER A 1 568 ? -36.87398 0.91901   -2.16258  1.000 80.45259  ? 567 SER A C   1 
ATOM   4349 O O   . SER A 1 568 ? -36.13262 0.51951   -1.25598  1.000 83.22368  ? 567 SER A O   1 
ATOM   4350 C CB  . SER A 1 568 ? -39.18011 0.46265   -1.25582  1.000 69.72495  ? 567 SER A CB  1 
ATOM   4351 O OG  . SER A 1 568 ? -38.47133 0.59713   -0.03829  1.000 71.85717  ? 567 SER A OG  1 
ATOM   4352 N N   . MET A 1 573 ? -34.96294 -1.54224  3.80142   1.000 83.27582  ? 572 MET A N   1 
ATOM   4353 C CA  . MET A 1 573 ? -35.97645 -2.39506  4.41970   1.000 83.48629  ? 572 MET A CA  1 
ATOM   4354 C C   . MET A 1 573 ? -36.26572 -2.04066  5.89528   1.000 84.97595  ? 572 MET A C   1 
ATOM   4355 O O   . MET A 1 573 ? -36.39406 -0.86527  6.24787   1.000 80.38984  ? 572 MET A O   1 
ATOM   4356 C CB  . MET A 1 573 ? -35.55432 -3.86351  4.33765   1.000 80.72574  ? 572 MET A CB  1 
ATOM   4357 C CG  . MET A 1 573 ? -35.20447 -4.38663  2.96568   1.000 77.47948  ? 572 MET A CG  1 
ATOM   4358 S SD  . MET A 1 573 ? -35.87620 -6.05644  2.72961   1.000 95.50421  ? 572 MET A SD  1 
ATOM   4359 C CE  . MET A 1 573 ? -35.88397 -6.74565  4.39001   1.000 64.83550  ? 572 MET A CE  1 
ATOM   4360 N N   . VAL A 1 574 ? -36.36805 -3.08421  6.72881   1.000 81.76869  ? 573 VAL A N   1 
ATOM   4361 C CA  . VAL A 1 574 ? -36.63811 -2.99448  8.16752   1.000 73.79597  ? 573 VAL A CA  1 
ATOM   4362 C C   . VAL A 1 574 ? -35.84629 -1.87628  8.83756   1.000 85.97089  ? 573 VAL A C   1 
ATOM   4363 O O   . VAL A 1 574 ? -34.63162 -1.98468  9.03343   1.000 86.63401  ? 573 VAL A O   1 
ATOM   4364 C CB  . VAL A 1 574 ? -36.32896 -4.34699  8.87578   1.000 81.53731  ? 573 VAL A CB  1 
ATOM   4365 C CG1 . VAL A 1 574 ? -37.08116 -4.45729  10.20342  1.000 75.57508  ? 573 VAL A CG1 1 
ATOM   4366 C CG2 . VAL A 1 574 ? -36.63071 -5.54009  7.96229   1.000 74.91452  ? 573 VAL A CG2 1 
ATOM   4367 N N   . SER A 1 579 ? -39.45988 -0.35835  13.43446  1.000 50.33796  ? 578 SER A N   1 
ATOM   4368 C CA  . SER A 1 579 ? -40.63768 -0.61123  14.27185  1.000 65.29510  ? 578 SER A CA  1 
ATOM   4369 C C   . SER A 1 579 ? -41.82657 -1.09038  13.42562  1.000 63.92914  ? 578 SER A C   1 
ATOM   4370 O O   . SER A 1 579 ? -41.98050 -0.65884  12.28159  1.000 57.15031  ? 578 SER A O   1 
ATOM   4371 C CB  . SER A 1 579 ? -41.01619 0.65489   15.06091  1.000 69.03901  ? 578 SER A CB  1 
ATOM   4372 O OG  . SER A 1 579 ? -42.39913 0.69404   15.39638  1.000 65.36205  ? 578 SER A OG  1 
ATOM   4373 N N   . TYR A 1 580 ? -42.65997 -1.98195  13.98766  1.000 62.62456  ? 579 TYR A N   1 
ATOM   4374 C CA  . TYR A 1 580 ? -43.78186 -2.52958  13.22284  1.000 62.25216  ? 579 TYR A CA  1 
ATOM   4375 C C   . TYR A 1 580 ? -44.82871 -1.46115  12.94032  1.000 64.45056  ? 579 TYR A C   1 
ATOM   4376 O O   . TYR A 1 580 ? -45.56000 -1.56011  11.94439  1.000 63.07449  ? 579 TYR A O   1 
ATOM   4377 C CB  . TYR A 1 580 ? -44.41627 -3.73047  13.95052  1.000 50.67859  ? 579 TYR A CB  1 
ATOM   4378 N N   . SER A 1 581 ? -44.88878 -0.42522  13.78844  1.000 71.51994  ? 580 SER A N   1 
ATOM   4379 C CA  . SER A 1 581 ? -45.82091 0.68665   13.59143  1.000 69.95306  ? 580 SER A CA  1 
ATOM   4380 C C   . SER A 1 581 ? -45.70056 1.29977   12.19732  1.000 65.00614  ? 580 SER A C   1 
ATOM   4381 O O   . SER A 1 581 ? -46.71232 1.65285   11.57977  1.000 60.15572  ? 580 SER A O   1 
ATOM   4382 C CB  . SER A 1 581 ? -45.59004 1.75402   14.66884  1.000 71.10188  ? 580 SER A CB  1 
ATOM   4383 O OG  . SER A 1 581 ? -44.24942 2.23240   14.66023  1.000 66.43018  ? 580 SER A OG  1 
ATOM   4384 N N   . THR A 1 582 ? -44.47385 1.42394   11.68049  1.000 65.52437  ? 581 THR A N   1 
ATOM   4385 C CA  . THR A 1 582 ? -44.22671 2.02239   10.37230  1.000 61.71430  ? 581 THR A CA  1 
ATOM   4386 C C   . THR A 1 582 ? -44.05347 1.01232   9.25018   1.000 64.74506  ? 581 THR A C   1 
ATOM   4387 O O   . THR A 1 582 ? -43.79998 1.41959   8.11342   1.000 75.38887  ? 581 THR A O   1 
ATOM   4388 C CB  . THR A 1 582 ? -42.98537 2.90117   10.41008  1.000 57.95908  ? 581 THR A CB  1 
ATOM   4389 O OG1 . THR A 1 582 ? -41.97894 2.26290   11.20797  1.000 60.69716  ? 581 THR A OG1 1 
ATOM   4390 C CG2 . THR A 1 582 ? -43.32666 4.27588   10.95563  1.000 66.54879  ? 581 THR A CG2 1 
ATOM   4391 N N   . LEU A 1 583 ? -44.15030 -0.28269  9.52424   1.000 59.51526  ? 582 LEU A N   1 
ATOM   4392 C CA  . LEU A 1 583 ? -44.13923 -1.23757  8.43080   1.000 55.27623  ? 582 LEU A CA  1 
ATOM   4393 C C   . LEU A 1 583 ? -45.52162 -1.77724  8.10590   1.000 60.31494  ? 582 LEU A C   1 
ATOM   4394 O O   . LEU A 1 583 ? -45.77567 -2.11396  6.94644   1.000 61.48609  ? 582 LEU A O   1 
ATOM   4395 C CB  . LEU A 1 583 ? -43.19907 -2.40437  8.74009   1.000 53.92203  ? 582 LEU A CB  1 
ATOM   4396 C CG  . LEU A 1 583 ? -41.76918 -2.05746  9.13122   1.000 50.27753  ? 582 LEU A CG  1 
ATOM   4397 C CD1 . LEU A 1 583 ? -41.21503 -3.13320  10.03888  1.000 47.97527  ? 582 LEU A CD1 1 
ATOM   4398 C CD2 . LEU A 1 583 ? -40.89790 -1.88141  7.90539   1.000 48.25609  ? 582 LEU A CD2 1 
ATOM   4399 N N   . VAL A 1 584 ? -46.42673 -1.84710  9.08996   1.000 61.03299  ? 583 VAL A N   1 
ATOM   4400 C CA  . VAL A 1 584 ? -47.72381 -2.47471  8.86314   1.000 55.19937  ? 583 VAL A CA  1 
ATOM   4401 C C   . VAL A 1 584 ? -48.47953 -1.74160  7.75614   1.000 58.21833  ? 583 VAL A C   1 
ATOM   4402 O O   . VAL A 1 584 ? -48.37309 -0.51926  7.60111   1.000 68.02565  ? 583 VAL A O   1 
ATOM   4403 C CB  . VAL A 1 584 ? -48.53331 -2.52175  10.17053  1.000 50.68100  ? 583 VAL A CB  1 
ATOM   4404 N N   . ASP A 1 585 ? -49.21880 -2.50801  6.95514   1.000 63.98451  ? 584 ASP A N   1 
ATOM   4405 C CA  . ASP A 1 585 ? -50.06212 -1.98438  5.88326   1.000 63.54877  ? 584 ASP A CA  1 
ATOM   4406 C C   . ASP A 1 585 ? -51.39149 -1.48851  6.45267   1.000 69.76545  ? 584 ASP A C   1 
ATOM   4407 O O   . ASP A 1 585 ? -51.97599 -2.11422  7.34667   1.000 63.66845  ? 584 ASP A O   1 
ATOM   4408 C CB  . ASP A 1 585 ? -50.30020 -3.09090  4.84868   1.000 59.94875  ? 584 ASP A CB  1 
ATOM   4409 C CG  . ASP A 1 585 ? -50.61538 -2.56706  3.45969   1.000 64.37509  ? 584 ASP A CG  1 
ATOM   4410 O OD1 . ASP A 1 585 ? -51.80906 -2.35128  3.16457   1.000 64.75815  ? 584 ASP A OD1 1 
ATOM   4411 O OD2 . ASP A 1 585 ? -49.66783 -2.40435  2.65338   1.000 62.17999  ? 584 ASP A OD2 1 
ATOM   4412 N N   . ASN A 1 586 ? -51.87757 -0.35985  5.92871   1.000 70.22238  ? 585 ASN A N   1 
ATOM   4413 C CA  . ASN A 1 586 ? -53.08577 0.23983   6.49530   1.000 77.82582  ? 585 ASN A CA  1 
ATOM   4414 C C   . ASN A 1 586 ? -54.33725 -0.53772  6.10368   1.000 72.18878  ? 585 ASN A C   1 
ATOM   4415 O O   . ASN A 1 586 ? -55.15704 -0.88710  6.96167   1.000 79.42368  ? 585 ASN A O   1 
ATOM   4416 C CB  . ASN A 1 586 ? -53.20397 1.70681   6.07339   1.000 75.16124  ? 585 ASN A CB  1 
ATOM   4417 C CG  . ASN A 1 586 ? -51.87783 2.29454   5.66434   1.000 80.62552  ? 585 ASN A CG  1 
ATOM   4418 O OD1 . ASN A 1 586 ? -51.45854 2.16630   4.51472   1.000 87.21211  ? 585 ASN A OD1 1 
ATOM   4419 N ND2 . ASN A 1 586 ? -51.18753 2.92001   6.61797   1.000 82.27925  ? 585 ASN A ND2 1 
ATOM   4420 N N   . GLU A 1 587 ? -54.50485 -0.82052  4.82121   1.000 60.46696  ? 586 GLU A N   1 
ATOM   4421 C CA  . GLU A 1 587 ? -55.72839 -1.43317  4.33389   1.000 61.77788  ? 586 GLU A CA  1 
ATOM   4422 C C   . GLU A 1 587 ? -55.47644 -2.82395  3.75396   1.000 57.98454  ? 586 GLU A C   1 
ATOM   4423 O O   . GLU A 1 587 ? -56.07510 -3.20594  2.74670   1.000 57.96087  ? 586 GLU A O   1 
ATOM   4424 C CB  . GLU A 1 587 ? -56.41384 -0.52310  3.31395   1.000 59.24287  ? 586 GLU A CB  1 
ATOM   4425 N N   . HIS A 1 588 ? -54.59274 -3.60573  4.38283   1.000 55.48913  ? 587 HIS A N   1 
ATOM   4426 C CA  . HIS A 1 588 ? -54.54070 -5.05602  4.17406   1.000 49.63645  ? 587 HIS A CA  1 
ATOM   4427 C C   . HIS A 1 588 ? -54.55365 -5.75999  5.52791   1.000 52.46358  ? 587 HIS A C   1 
ATOM   4428 O O   . HIS A 1 588 ? -53.53281 -5.80365  6.22310   1.000 55.90183  ? 587 HIS A O   1 
ATOM   4429 C CB  . HIS A 1 588 ? -53.32310 -5.50586  3.38075   1.000 48.76117  ? 587 HIS A CB  1 
ATOM   4430 C CG  . HIS A 1 588 ? -53.34711 -6.97479  3.06326   1.000 52.74709  ? 587 HIS A CG  1 
ATOM   4431 N ND1 . HIS A 1 588 ? -52.32326 -7.62226  2.40652   1.000 49.74359  ? 587 HIS A ND1 1 
ATOM   4432 C CD2 . HIS A 1 588 ? -54.28844 -7.91949  3.30630   1.000 48.97091  ? 587 HIS A CD2 1 
ATOM   4433 C CE1 . HIS A 1 588 ? -52.62292 -8.90145  2.27421   1.000 47.80979  ? 587 HIS A CE1 1 
ATOM   4434 N NE2 . HIS A 1 588 ? -53.81216 -9.10755  2.80958   1.000 46.82109  ? 587 HIS A NE2 1 
ATOM   4435 N N   . ALA A 1 589 ? -55.69273 -6.34001  5.88647   1.000 45.37653  ? 588 ALA A N   1 
ATOM   4436 C CA  . ALA A 1 589 ? -55.80361 -7.14245  7.09395   1.000 43.23819  ? 588 ALA A CA  1 
ATOM   4437 C C   . ALA A 1 589 ? -55.72896 -8.61700  6.73330   1.000 43.37591  ? 588 ALA A C   1 
ATOM   4438 O O   . ALA A 1 589 ? -56.22117 -9.04196  5.68685   1.000 44.42744  ? 588 ALA A O   1 
ATOM   4439 C CB  . ALA A 1 589 ? -57.10542 -6.86167  7.84635   1.000 36.68386  ? 588 ALA A CB  1 
ATOM   4440 N N   . LEU A 1 590 ? -55.08694 -9.38906  7.58983   1.000 42.36902  ? 589 LEU A N   1 
ATOM   4441 C CA  . LEU A 1 590 ? -55.00334 -10.82128 7.40857   1.000 38.02655  ? 589 LEU A CA  1 
ATOM   4442 C C   . LEU A 1 590 ? -55.88768 -11.47164 8.45375   1.000 43.71362  ? 589 LEU A C   1 
ATOM   4443 O O   . LEU A 1 590 ? -55.90619 -11.05296 9.61936   1.000 42.99565  ? 589 LEU A O   1 
ATOM   4444 C CB  . LEU A 1 590 ? -53.56749 -11.32251 7.52896   1.000 39.44823  ? 589 LEU A CB  1 
ATOM   4445 C CG  . LEU A 1 590 ? -52.61934 -10.86093 6.43364   1.000 35.27802  ? 589 LEU A CG  1 
ATOM   4446 C CD1 . LEU A 1 590 ? -51.21532 -11.24507 6.79663   1.000 39.00270  ? 589 LEU A CD1 1 
ATOM   4447 C CD2 . LEU A 1 590 ? -53.01732 -11.48493 5.11207   1.000 40.04082  ? 589 LEU A CD2 1 
ATOM   4448 N N   . VAL A 1 591 ? -56.64009 -12.47257 8.01293   1.000 39.42903  ? 590 VAL A N   1 
ATOM   4449 C CA  . VAL A 1 591 ? -57.59118 -13.16023 8.86893   1.000 39.24171  ? 590 VAL A CA  1 
ATOM   4450 C C   . VAL A 1 591 ? -56.83426 -14.21199 9.66405   1.000 46.78001  ? 590 VAL A C   1 
ATOM   4451 O O   . VAL A 1 591 ? -56.31735 -15.17630 9.08959   1.000 51.05919  ? 590 VAL A O   1 
ATOM   4452 C CB  . VAL A 1 591 ? -58.71496 -13.79344 8.05693   1.000 31.37819  ? 590 VAL A CB  1 
ATOM   4453 C CG1 . VAL A 1 591 ? -59.50861 -14.74382 8.94906   1.000 27.02896  ? 590 VAL A CG1 1 
ATOM   4454 C CG2 . VAL A 1 591 ? -59.56134 -12.70225 7.45801   1.000 23.34199  ? 590 VAL A CG2 1 
ATOM   4455 N N   . ASN A 1 592 ? -56.78645 -14.02545 10.99491  1.000 40.01020  ? 591 ASN A N   1 
ATOM   4456 C CA  . ASN A 1 592 ? -56.07158 -14.86655 11.93528  1.000 37.90013  ? 591 ASN A CA  1 
ATOM   4457 C C   . ASN A 1 592 ? -56.66501 -16.26456 11.87365  1.000 40.65324  ? 591 ASN A C   1 
ATOM   4458 O O   . ASN A 1 592 ? -57.80978 -16.48019 12.29154  1.000 40.79859  ? 591 ASN A O   1 
ATOM   4459 C CB  . ASN A 1 592 ? -56.15113 -14.26186 13.33585  1.000 37.96499  ? 591 ASN A CB  1 
ATOM   4460 C CG  . ASN A 1 592 ? -55.45347 -15.10205 14.39279  1.000 42.27643  ? 591 ASN A CG  1 
ATOM   4461 O OD1 . ASN A 1 592 ? -55.00702 -16.22042 14.13071  1.000 40.74956  ? 591 ASN A OD1 1 
ATOM   4462 N ND2 . ASN A 1 592 ? -55.33993 -14.54729 15.60481  1.000 42.16897  ? 591 ASN A ND2 1 
ATOM   4463 N N   . PRO A 1 593 ? -55.91790 -17.23121 11.33240  1.000 41.61984  ? 592 PRO A N   1 
ATOM   4464 C CA  . PRO A 1 593 ? -56.47198 -18.58923 11.19178  1.000 37.36433  ? 592 PRO A CA  1 
ATOM   4465 C C   . PRO A 1 593 ? -56.97128 -19.18262 12.49400  1.000 42.64103  ? 592 PRO A C   1 
ATOM   4466 O O   . PRO A 1 593 ? -57.98506 -19.88914 12.48391  1.000 48.43050  ? 592 PRO A O   1 
ATOM   4467 C CB  . PRO A 1 593 ? -55.29895 -19.39166 10.61163  1.000 37.89617  ? 592 PRO A CB  1 
ATOM   4468 C CG  . PRO A 1 593 ? -54.08412 -18.50000 10.75177  1.000 41.14272  ? 592 PRO A CG  1 
ATOM   4469 C CD  . PRO A 1 593 ? -54.59107 -17.09948 10.70866  1.000 34.22594  ? 592 PRO A CD  1 
ATOM   4470 N N   . ILE A 1 594 ? -56.31543 -18.90738 13.62691  1.000 44.15901  ? 593 ILE A N   1 
ATOM   4471 C CA  . ILE A 1 594 ? -56.72567 -19.56292 14.86948  1.000 46.19926  ? 593 ILE A CA  1 
ATOM   4472 C C   . ILE A 1 594 ? -57.85947 -18.82973 15.56632  1.000 48.06624  ? 593 ILE A C   1 
ATOM   4473 O O   . ILE A 1 594 ? -58.42097 -19.36528 16.53465  1.000 47.27026  ? 593 ILE A O   1 
ATOM   4474 C CB  . ILE A 1 594 ? -55.54276 -19.75687 15.84449  1.000 41.61855  ? 593 ILE A CB  1 
ATOM   4475 C CG1 . ILE A 1 594 ? -55.07877 -18.44189 16.45918  1.000 42.17567  ? 593 ILE A CG1 1 
ATOM   4476 C CG2 . ILE A 1 594 ? -54.37337 -20.40232 15.14271  1.000 42.02645  ? 593 ILE A CG2 1 
ATOM   4477 C CD1 . ILE A 1 594 ? -54.01357 -18.64107 17.51829  1.000 38.82588  ? 593 ILE A CD1 1 
ATOM   4478 N N   . ALA A 1 595 ? -58.23790 -17.63784 15.08830  1.000 48.16458  ? 594 ALA A N   1 
ATOM   4479 C CA  . ALA A 1 595 ? -59.31414 -16.89221 15.73523  1.000 44.57819  ? 594 ALA A CA  1 
ATOM   4480 C C   . ALA A 1 595 ? -60.61574 -17.66536 15.71485  1.000 48.59987  ? 594 ALA A C   1 
ATOM   4481 O O   . ALA A 1 595 ? -61.39674 -17.58711 16.66612  1.000 52.12195  ? 594 ALA A O   1 
ATOM   4482 C CB  . ALA A 1 595 ? -59.51108 -15.54018 15.06435  1.000 37.44510  ? 594 ALA A CB  1 
ATOM   4483 N N   . GLY A 1 596 ? -60.85175 -18.44086 14.65942  1.000 55.00867  ? 595 GLY A N   1 
ATOM   4484 C CA  . GLY A 1 596 ? -62.08034 -19.20553 14.54681  1.000 60.47770  ? 595 GLY A CA  1 
ATOM   4485 C C   . GLY A 1 596 ? -62.34347 -20.15985 15.69874  1.000 72.89528  ? 595 GLY A C   1 
ATOM   4486 O O   . GLY A 1 596 ? -63.46075 -20.68203 15.79976  1.000 79.59945  ? 595 GLY A O   1 
ATOM   4487 N N   . HIS A 1 597 ? -61.35660 -20.40163 16.56635  1.000 68.84850  ? 596 HIS A N   1 
ATOM   4488 C CA  . HIS A 1 597 ? -61.51332 -21.33709 17.67330  1.000 63.35310  ? 596 HIS A CA  1 
ATOM   4489 C C   . HIS A 1 597 ? -61.40510 -20.63885 19.02031  1.000 66.20324  ? 596 HIS A C   1 
ATOM   4490 O O   . HIS A 1 597 ? -61.34334 -21.32200 20.05266  1.000 72.86209  ? 596 HIS A O   1 
ATOM   4491 C CB  . HIS A 1 597 ? -60.47860 -22.47493 17.59945  1.000 66.72253  ? 596 HIS A CB  1 
ATOM   4492 C CG  . HIS A 1 597 ? -60.23533 -23.02542 16.21689  1.000 70.42539  ? 596 HIS A CG  1 
ATOM   4493 N ND1 . HIS A 1 597 ? -59.88117 -22.23871 15.13697  1.000 64.94348  ? 596 HIS A ND1 1 
ATOM   4494 C CD2 . HIS A 1 597 ? -60.26918 -24.29924 15.75244  1.000 68.82604  ? 596 HIS A CD2 1 
ATOM   4495 C CE1 . HIS A 1 597 ? -59.72348 -22.99948 14.06803  1.000 62.82896  ? 596 HIS A CE1 1 
ATOM   4496 N NE2 . HIS A 1 597 ? -59.94664 -24.25467 14.41562  1.000 67.98048  ? 596 HIS A NE2 1 
ATOM   4497 N N   . ARG A 1 598 ? -61.39893 -19.30218 19.02803  1.000 65.48697  ? 597 ARG A N   1 
ATOM   4498 C CA  . ARG A 1 598 ? -61.13116 -18.46480 20.20953  1.000 63.21179  ? 597 ARG A CA  1 
ATOM   4499 C C   . ARG A 1 598 ? -61.68599 -19.02722 21.51261  1.000 61.25812  ? 597 ARG A C   1 
ATOM   4500 O O   . ARG A 1 598 ? -60.99785 -19.77880 22.20704  1.000 69.05468  ? 597 ARG A O   1 
ATOM   4501 C CB  . ARG A 1 598 ? -61.68804 -17.04779 19.98537  1.000 60.62828  ? 597 ARG A CB  1 
ATOM   4502 N N   . ALA B 1 17  ? 11.03032  -5.20684  2.73526   1.000 43.16557  ? 16  ALA B N   1 
ATOM   4503 C CA  . ALA B 1 17  ? 9.89021   -4.33168  3.00443   1.000 59.13892  ? 16  ALA B CA  1 
ATOM   4504 C C   . ALA B 1 17  ? 10.01881  -2.99806  2.24441   1.000 57.95284  ? 16  ALA B C   1 
ATOM   4505 O O   . ALA B 1 17  ? 10.83708  -2.87184  1.33784   1.000 55.62774  ? 16  ALA B O   1 
ATOM   4506 C CB  . ALA B 1 17  ? 9.74519   -4.08381  4.51240   1.000 55.70374  ? 16  ALA B CB  1 
ATOM   4507 N N   . CYS B 1 18  ? 9.21564   -2.00717  2.63291   1.000 53.22622  ? 17  CYS B N   1 
ATOM   4508 C CA  . CYS B 1 18  ? 9.09469   -0.73784  1.92091   1.000 49.15840  ? 17  CYS B CA  1 
ATOM   4509 C C   . CYS B 1 18  ? 9.77412   0.36922   2.72333   1.000 55.47862  ? 17  CYS B C   1 
ATOM   4510 O O   . CYS B 1 18  ? 9.19675   0.89914   3.68240   1.000 58.92127  ? 17  CYS B O   1 
ATOM   4511 C CB  . CYS B 1 18  ? 7.62504   -0.41431  1.67697   1.000 51.24514  ? 17  CYS B CB  1 
ATOM   4512 S SG  . CYS B 1 18  ? 6.51846   -1.70018  2.27952   1.000 77.52067  ? 17  CYS B SG  1 
ATOM   4513 N N   . SER B 1 19  ? 10.96831  0.76865   2.27961   1.000 50.11274  ? 18  SER B N   1 
ATOM   4514 C CA  . SER B 1 19  ? 11.83154  1.68081   3.02304   1.000 47.36601  ? 18  SER B CA  1 
ATOM   4515 C C   . SER B 1 19  ? 11.73959  3.15856   2.62613   1.000 49.10726  ? 18  SER B C   1 
ATOM   4516 O O   . SER B 1 19  ? 12.37437  3.98690   3.28024   1.000 52.39772  ? 18  SER B O   1 
ATOM   4517 C CB  . SER B 1 19  ? 13.27419  1.21393   2.87990   1.000 48.76233  ? 18  SER B CB  1 
ATOM   4518 O OG  . SER B 1 19  ? 13.33957  0.20548   1.89704   1.000 51.22698  ? 18  SER B OG  1 
ATOM   4519 N N   . TYR B 1 20  ? 10.98674  3.53400   1.59089   1.000 50.98040  ? 19  TYR B N   1 
ATOM   4520 C CA  . TYR B 1 20  ? 10.97658  4.93223   1.16503   1.000 50.82452  ? 19  TYR B CA  1 
ATOM   4521 C C   . TYR B 1 20  ? 9.63251   5.60183   1.36746   1.000 47.40280  ? 19  TYR B C   1 
ATOM   4522 O O   . TYR B 1 20  ? 9.33775   6.58925   0.68590   1.000 42.87290  ? 19  TYR B O   1 
ATOM   4523 C CB  . TYR B 1 20  ? 11.38871  5.07188   -0.29808  1.000 44.55194  ? 19  TYR B CB  1 
ATOM   4524 C CG  . TYR B 1 20  ? 12.70843  4.43037   -0.63844  1.000 46.62634  ? 19  TYR B CG  1 
ATOM   4525 C CD1 . TYR B 1 20  ? 12.81374  3.05446   -0.77174  1.000 48.16329  ? 19  TYR B CD1 1 
ATOM   4526 C CD2 . TYR B 1 20  ? 13.84189  5.20121   -0.84336  1.000 41.94814  ? 19  TYR B CD2 1 
ATOM   4527 C CE1 . TYR B 1 20  ? 14.00064  2.46163   -1.09770  1.000 50.92881  ? 19  TYR B CE1 1 
ATOM   4528 C CE2 . TYR B 1 20  ? 15.03668  4.62076   -1.17263  1.000 47.88364  ? 19  TYR B CE2 1 
ATOM   4529 C CZ  . TYR B 1 20  ? 15.11717  3.24340   -1.30040  1.000 57.05514  ? 19  TYR B CZ  1 
ATOM   4530 O OH  . TYR B 1 20  ? 16.31552  2.62867   -1.63127  1.000 57.20510  ? 19  TYR B OH  1 
ATOM   4531 N N   . ARG B 1 21  ? 8.82957   5.09408   2.30225   1.000 45.84710  ? 20  ARG B N   1 
ATOM   4532 C CA  . ARG B 1 21  ? 7.44492   5.52731   2.42092   1.000 43.53818  ? 20  ARG B CA  1 
ATOM   4533 C C   . ARG B 1 21  ? 7.35552   7.04039   2.56541   1.000 49.01329  ? 20  ARG B C   1 
ATOM   4534 O O   . ARG B 1 21  ? 6.56775   7.69797   1.87421   1.000 49.04914  ? 20  ARG B O   1 
ATOM   4535 C CB  . ARG B 1 21  ? 6.78566   4.82775   3.61245   1.000 51.77116  ? 20  ARG B CB  1 
ATOM   4536 C CG  . ARG B 1 21  ? 6.08872   3.49399   3.30011   1.000 56.57160  ? 20  ARG B CG  1 
ATOM   4537 C CD  . ARG B 1 21  ? 5.43856   2.86266   4.54942   1.000 54.04560  ? 20  ARG B CD  1 
ATOM   4538 N NE  . ARG B 1 21  ? 4.39464   3.70625   5.12977   1.000 58.25961  ? 20  ARG B NE  1 
ATOM   4539 C CZ  . ARG B 1 21  ? 3.19193   3.90323   4.59463   1.000 65.00411  ? 20  ARG B CZ  1 
ATOM   4540 N NH1 . ARG B 1 21  ? 2.81123   3.27906   3.49059   1.000 60.77368  ? 20  ARG B NH1 1 
ATOM   4541 N NH2 . ARG B 1 21  ? 2.34885   4.75194   5.18004   1.000 60.14158  ? 20  ARG B NH2 1 
ATOM   4542 N N   . GLN B 1 22  ? 8.18081   7.61955   3.44464   1.000 53.52472  ? 21  GLN B N   1 
ATOM   4543 C CA  . GLN B 1 22  ? 8.05512   9.05152   3.71287   1.000 51.50036  ? 21  GLN B CA  1 
ATOM   4544 C C   . GLN B 1 22  ? 8.54024   9.89184   2.54423   1.000 49.06804  ? 21  GLN B C   1 
ATOM   4545 O O   . GLN B 1 22  ? 8.01520   10.99125  2.31764   1.000 44.23676  ? 21  GLN B O   1 
ATOM   4546 C CB  . GLN B 1 22  ? 8.81614   9.43131   4.97627   1.000 53.50333  ? 21  GLN B CB  1 
ATOM   4547 C CG  . GLN B 1 22  ? 8.69953   10.90751  5.32617   1.000 54.15976  ? 21  GLN B CG  1 
ATOM   4548 C CD  . GLN B 1 22  ? 7.27349   11.32880  5.63751   1.000 57.97932  ? 21  GLN B CD  1 
ATOM   4549 O OE1 . GLN B 1 22  ? 6.54314   10.61672  6.33915   1.000 65.94045  ? 21  GLN B OE1 1 
ATOM   4550 N NE2 . GLN B 1 22  ? 6.86495   12.48875  5.11501   1.000 51.57801  ? 21  GLN B NE2 1 
ATOM   4551 N N   . VAL B 1 23  ? 9.54880   9.40134   1.81229   1.000 48.01816  ? 22  VAL B N   1 
ATOM   4552 C CA  . VAL B 1 23  ? 9.94455   10.02781  0.54955   1.000 44.80199  ? 22  VAL B CA  1 
ATOM   4553 C C   . VAL B 1 23  ? 8.72189   10.24054  -0.33316  1.000 47.02532  ? 22  VAL B C   1 
ATOM   4554 O O   . VAL B 1 23  ? 8.30961   11.37524  -0.60452  1.000 44.67582  ? 22  VAL B O   1 
ATOM   4555 C CB  . VAL B 1 23  ? 10.99477  9.17031   -0.17159  1.000 42.32597  ? 22  VAL B CB  1 
ATOM   4556 C CG1 . VAL B 1 23  ? 11.20790  9.67667   -1.59490  1.000 42.07347  ? 22  VAL B CG1 1 
ATOM   4557 C CG2 . VAL B 1 23  ? 12.28591  9.16819   0.60381   1.000 42.38941  ? 22  VAL B CG2 1 
ATOM   4558 N N   . TYR B 1 24  ? 8.10114   9.13502   -0.75558  1.000 43.60940  ? 23  TYR B N   1 
ATOM   4559 C CA  . TYR B 1 24  ? 6.92684   9.21481   -1.60878  1.000 43.15928  ? 23  TYR B CA  1 
ATOM   4560 C C   . TYR B 1 24  ? 5.77634   9.93326   -0.92958  1.000 46.58722  ? 23  TYR B C   1 
ATOM   4561 O O   . TYR B 1 24  ? 4.97660   10.59208  -1.61001  1.000 47.91733  ? 23  TYR B O   1 
ATOM   4562 C CB  . TYR B 1 24  ? 6.51417   7.81036   -2.05628  1.000 51.59936  ? 23  TYR B CB  1 
ATOM   4563 C CG  . TYR B 1 24  ? 7.49480   7.28762   -3.07214  1.000 49.85242  ? 23  TYR B CG  1 
ATOM   4564 C CD1 . TYR B 1 24  ? 7.38960   7.64478   -4.41142  1.000 40.63939  ? 23  TYR B CD1 1 
ATOM   4565 C CD2 . TYR B 1 24  ? 8.56761   6.49336   -2.68440  1.000 47.78683  ? 23  TYR B CD2 1 
ATOM   4566 C CE1 . TYR B 1 24  ? 8.30927   7.21178   -5.33143  1.000 37.08427  ? 23  TYR B CE1 1 
ATOM   4567 C CE2 . TYR B 1 24  ? 9.49168   6.05325   -3.60896  1.000 46.12875  ? 23  TYR B CE2 1 
ATOM   4568 C CZ  . TYR B 1 24  ? 9.35267   6.42086   -4.92787  1.000 42.12159  ? 23  TYR B CZ  1 
ATOM   4569 O OH  . TYR B 1 24  ? 10.26519  5.98508   -5.84959  1.000 50.07354  ? 23  TYR B OH  1 
ATOM   4570 N N   . ASN B 1 25  ? 5.67663   9.83907   0.40029   1.000 50.23443  ? 24  ASN B N   1 
ATOM   4571 C CA  . ASN B 1 25  ? 4.59951   10.54516  1.09088   1.000 50.76518  ? 24  ASN B CA  1 
ATOM   4572 C C   . ASN B 1 25  ? 4.73599   12.05223  0.91845   1.000 47.80652  ? 24  ASN B C   1 
ATOM   4573 O O   . ASN B 1 25  ? 3.74361   12.74629  0.66675   1.000 48.47283  ? 24  ASN B O   1 
ATOM   4574 C CB  . ASN B 1 25  ? 4.56082   10.17238  2.57337   1.000 45.85220  ? 24  ASN B CB  1 
ATOM   4575 C CG  . ASN B 1 25  ? 3.20662   10.47268  3.20744   1.000 53.67940  ? 24  ASN B CG  1 
ATOM   4576 O OD1 . ASN B 1 25  ? 2.29349   10.98560  2.55771   1.000 57.30979  ? 24  ASN B OD1 1 
ATOM   4577 N ND2 . ASN B 1 25  ? 3.07854   10.16832  4.48338   1.000 64.51161  ? 24  ASN B ND2 1 
ATOM   4578 N N   . THR B 1 26  ? 5.95936   12.57366  1.03591   1.000 47.82576  ? 25  THR B N   1 
ATOM   4579 C CA  . THR B 1 26  ? 6.18801   13.99734  0.80855   1.000 50.44998  ? 25  THR B CA  1 
ATOM   4580 C C   . THR B 1 26  ? 5.94625   14.35993  -0.65766  1.000 49.94666  ? 25  THR B C   1 
ATOM   4581 O O   . THR B 1 26  ? 5.19983   15.30470  -0.96010  1.000 44.92732  ? 25  THR B O   1 
ATOM   4582 C CB  . THR B 1 26  ? 7.61127   14.36959  1.23650   1.000 55.50681  ? 25  THR B CB  1 
ATOM   4583 O OG1 . THR B 1 26  ? 7.96073   13.65454  2.43071   1.000 54.38575  ? 25  THR B OG1 1 
ATOM   4584 C CG2 . THR B 1 26  ? 7.71586   15.85808  1.51070   1.000 53.88492  ? 25  THR B CG2 1 
ATOM   4585 N N   . ARG B 1 27  ? 6.57258   13.61700  -1.58329  1.000 47.26432  ? 26  ARG B N   1 
ATOM   4586 C CA  . ARG B 1 27  ? 6.26491   13.74867  -3.00657  1.000 45.01579  ? 26  ARG B CA  1 
ATOM   4587 C C   . ARG B 1 27  ? 4.77225   13.86064  -3.21250  1.000 44.13144  ? 26  ARG B C   1 
ATOM   4588 O O   . ARG B 1 27  ? 4.27735   14.84024  -3.77934  1.000 43.16282  ? 26  ARG B O   1 
ATOM   4589 C CB  . ARG B 1 27  ? 6.79222   12.55189  -3.79875  1.000 41.27511  ? 26  ARG B CB  1 
ATOM   4590 C CG  . ARG B 1 27  ? 8.08590   12.80169  -4.54260  1.000 46.06613  ? 26  ARG B CG  1 
ATOM   4591 C CD  . ARG B 1 27  ? 8.45428   11.59799  -5.38223  1.000 44.32756  ? 26  ARG B CD  1 
ATOM   4592 N NE  . ARG B 1 27  ? 9.85040   11.20927  -5.22928  1.000 40.86557  ? 26  ARG B NE  1 
ATOM   4593 C CZ  . ARG B 1 27  ? 10.47062  10.37702  -6.05207  1.000 46.00057  ? 26  ARG B CZ  1 
ATOM   4594 N NH1 . ARG B 1 27  ? 9.83909   9.83668   -7.08355  1.000 51.06869  ? 26  ARG B NH1 1 
ATOM   4595 N NH2 . ARG B 1 27  ? 11.75389  10.08645  -5.84169  1.000 41.90066  ? 26  ARG B NH2 1 
ATOM   4596 N N   . LEU B 1 28  ? 4.04510   12.85963  -2.71111  1.000 44.01610  ? 27  LEU B N   1 
ATOM   4597 C CA  . LEU B 1 28  ? 2.59879   12.85312  -2.84919  1.000 41.87344  ? 27  LEU B CA  1 
ATOM   4598 C C   . LEU B 1 28  ? 1.99486   14.16712  -2.39246  1.000 46.00781  ? 27  LEU B C   1 
ATOM   4599 O O   . LEU B 1 28  ? 1.06845   14.68110  -3.02505  1.000 43.40926  ? 27  LEU B O   1 
ATOM   4600 C CB  . LEU B 1 28  ? 2.00615   11.69569  -2.06084  1.000 42.23339  ? 27  LEU B CB  1 
ATOM   4601 C CG  . LEU B 1 28  ? 1.32208   10.68650  -2.95690  1.000 44.60673  ? 27  LEU B CG  1 
ATOM   4602 C CD1 . LEU B 1 28  ? 0.45223   11.43998  -3.95023  1.000 42.05112  ? 27  LEU B CD1 1 
ATOM   4603 C CD2 . LEU B 1 28  ? 2.36542   9.82384   -3.65393  1.000 41.48745  ? 27  LEU B CD2 1 
ATOM   4604 N N   . ALA B 1 29  ? 2.52188   14.74063  -1.30457  1.000 49.11756  ? 28  ALA B N   1 
ATOM   4605 C CA  . ALA B 1 29  ? 1.91724   15.94454  -0.74086  1.000 49.41105  ? 28  ALA B CA  1 
ATOM   4606 C C   . ALA B 1 29  ? 2.33489   17.19145  -1.50793  1.000 49.80630  ? 28  ALA B C   1 
ATOM   4607 O O   . ALA B 1 29  ? 1.52580   18.12268  -1.66962  1.000 43.46930  ? 28  ALA B O   1 
ATOM   4608 C CB  . ALA B 1 29  ? 2.27915   16.07050  0.73795   1.000 46.25115  ? 28  ALA B CB  1 
ATOM   4609 N N   . ARG B 1 30  ? 3.58239   17.21348  -1.99421  1.000 46.52286  ? 29  ARG B N   1 
ATOM   4610 C CA  . ARG B 1 30  ? 4.02335   18.28972  -2.87610  1.000 46.54688  ? 29  ARG B CA  1 
ATOM   4611 C C   . ARG B 1 30  ? 3.12043   18.39379  -4.10351  1.000 48.86770  ? 29  ARG B C   1 
ATOM   4612 O O   . ARG B 1 30  ? 2.62858   19.47859  -4.43687  1.000 49.50054  ? 29  ARG B O   1 
ATOM   4613 C CB  . ARG B 1 30  ? 5.47621   18.05845  -3.28070  1.000 44.40607  ? 29  ARG B CB  1 
ATOM   4614 C CG  . ARG B 1 30  ? 6.07197   19.17738  -4.07633  1.000 50.30924  ? 29  ARG B CG  1 
ATOM   4615 C CD  . ARG B 1 30  ? 7.58226   19.03254  -4.18063  1.000 60.52842  ? 29  ARG B CD  1 
ATOM   4616 N NE  . ARG B 1 30  ? 7.99536   18.31596  -5.38245  1.000 56.17606  ? 29  ARG B NE  1 
ATOM   4617 C CZ  . ARG B 1 30  ? 8.18012   18.89098  -6.56329  1.000 67.81735  ? 29  ARG B CZ  1 
ATOM   4618 N NH1 . ARG B 1 30  ? 7.89950   20.17280  -6.76317  1.000 62.16680  ? 29  ARG B NH1 1 
ATOM   4619 N NH2 . ARG B 1 30  ? 8.64625   18.16127  -7.57315  1.000 77.58350  ? 29  ARG B NH2 1 
ATOM   4620 N N   . LYS B 1 31  ? 2.86086   17.26095  -4.76866  1.000 45.60001  ? 30  LYS B N   1 
ATOM   4621 C CA  . LYS B 1 31  ? 1.94626   17.26281  -5.90777  1.000 43.49252  ? 30  LYS B CA  1 
ATOM   4622 C C   . LYS B 1 31  ? 0.55319   17.73695  -5.49885  1.000 42.71559  ? 30  LYS B C   1 
ATOM   4623 O O   . LYS B 1 31  ? -0.12034  18.42559  -6.26875  1.000 47.64098  ? 30  LYS B O   1 
ATOM   4624 C CB  . LYS B 1 31  ? 1.90063   15.86690  -6.54759  1.000 39.20785  ? 30  LYS B CB  1 
ATOM   4625 C CG  . LYS B 1 31  ? 0.72959   15.60357  -7.48752  1.000 36.42362  ? 30  LYS B CG  1 
ATOM   4626 C CD  . LYS B 1 31  ? 1.11233   14.55913  -8.50525  1.000 45.51973  ? 30  LYS B CD  1 
ATOM   4627 C CE  . LYS B 1 31  ? -0.02101  13.60766  -8.89750  1.000 46.92022  ? 30  LYS B CE  1 
ATOM   4628 N NZ  . LYS B 1 31  ? 0.53883   12.60530  -9.88088  1.000 40.84482  ? 30  LYS B NZ  1 
ATOM   4629 N N   . ILE B 1 32  ? 0.10504   17.39594  -4.28819  1.000 45.39163  ? 31  ILE B N   1 
ATOM   4630 C CA  . ILE B 1 32  ? -1.21036  17.85911  -3.84626  1.000 52.08493  ? 31  ILE B CA  1 
ATOM   4631 C C   . ILE B 1 32  ? -1.24972  19.38175  -3.83192  1.000 56.05379  ? 31  ILE B C   1 
ATOM   4632 O O   . ILE B 1 32  ? -2.21973  20.00108  -4.29859  1.000 51.77391  ? 31  ILE B O   1 
ATOM   4633 C CB  . ILE B 1 32  ? -1.57184  17.27661  -2.46332  1.000 45.78907  ? 31  ILE B CB  1 
ATOM   4634 C CG1 . ILE B 1 32  ? -1.73092  15.77178  -2.53091  1.000 41.50284  ? 31  ILE B CG1 1 
ATOM   4635 C CG2 . ILE B 1 32  ? -2.86659  17.87718  -1.94426  1.000 40.75629  ? 31  ILE B CG2 1 
ATOM   4636 C CD1 . ILE B 1 32  ? -1.57989  15.11288  -1.19643  1.000 48.12828  ? 31  ILE B CD1 1 
ATOM   4637 N N   . LEU B 1 33  ? -0.18531  20.00984  -3.31629  1.000 51.97622  ? 32  LEU B N   1 
ATOM   4638 C CA  . LEU B 1 33  ? -0.18147  21.46234  -3.17927  1.000 53.96482  ? 32  LEU B CA  1 
ATOM   4639 C C   . LEU B 1 33  ? 0.04867   22.15399  -4.51456  1.000 50.49456  ? 32  LEU B C   1 
ATOM   4640 O O   . LEU B 1 33  ? -0.61875  23.14589  -4.82046  1.000 49.36804  ? 32  LEU B O   1 
ATOM   4641 C CB  . LEU B 1 33  ? 0.87973   21.89519  -2.17019  1.000 53.53510  ? 32  LEU B CB  1 
ATOM   4642 C CG  . LEU B 1 33  ? 0.42606   21.91219  -0.71350  1.000 50.25328  ? 32  LEU B CG  1 
ATOM   4643 C CD1 . LEU B 1 33  ? 1.63652   22.02073  0.19314   1.000 48.42745  ? 32  LEU B CD1 1 
ATOM   4644 C CD2 . LEU B 1 33  ? -0.54140  23.04872  -0.47946  1.000 48.23150  ? 32  LEU B CD2 1 
ATOM   4645 N N   . ALA B 1 34  ? 0.98372   21.64261  -5.31761  1.000 50.54003  ? 33  ALA B N   1 
ATOM   4646 C CA  . ALA B 1 34  ? 1.27888   22.26096  -6.60511  1.000 46.59389  ? 33  ALA B CA  1 
ATOM   4647 C C   . ALA B 1 34  ? 0.04885   22.25861  -7.49888  1.000 52.25644  ? 33  ALA B C   1 
ATOM   4648 O O   . ALA B 1 34  ? -0.31601  23.28251  -8.08954  1.000 56.74513  ? 33  ALA B O   1 
ATOM   4649 C CB  . ALA B 1 34  ? 2.44202   21.53358  -7.28089  1.000 40.74263  ? 33  ALA B CB  1 
ATOM   4650 N N   . GLU B 1 35  ? -0.62525  21.11960  -7.58379  1.000 49.41956  ? 34  GLU B N   1 
ATOM   4651 C CA  . GLU B 1 35  ? -1.74528  21.02535  -8.49801  1.000 50.51605  ? 34  GLU B CA  1 
ATOM   4652 C C   . GLU B 1 35  ? -2.96883  21.77369  -7.97617  1.000 53.16637  ? 34  GLU B C   1 
ATOM   4653 O O   . GLU B 1 35  ? -3.70774  22.36358  -8.76861  1.000 58.28067  ? 34  GLU B O   1 
ATOM   4654 C CB  . GLU B 1 35  ? -2.04590  19.55489  -8.78368  1.000 49.03932  ? 34  GLU B CB  1 
ATOM   4655 C CG  . GLU B 1 35  ? -1.00936  18.87150  -9.71327  1.000 53.78765  ? 34  GLU B CG  1 
ATOM   4656 C CD  . GLU B 1 35  ? -0.53242  19.75087  -10.89046 1.000 55.06450  ? 34  GLU B CD  1 
ATOM   4657 O OE1 . GLU B 1 35  ? -1.38230  20.17905  -11.71047 1.000 52.93851  ? 34  GLU B OE1 1 
ATOM   4658 O OE2 . GLU B 1 35  ? 0.69549   19.99941  -10.99213 1.000 49.25691  ? 34  GLU B OE2 1 
ATOM   4659 N N   . PHE B 1 36  ? -3.19731  21.79762  -6.66260  1.000 58.39992  ? 35  PHE B N   1 
ATOM   4660 C CA  . PHE B 1 36  ? -4.34155  22.56398  -6.17378  1.000 58.24168  ? 35  PHE B CA  1 
ATOM   4661 C C   . PHE B 1 36  ? -4.05289  24.05815  -6.16339  1.000 58.46552  ? 35  PHE B C   1 
ATOM   4662 O O   . PHE B 1 36  ? -4.98910  24.86155  -6.25493  1.000 61.86108  ? 35  PHE B O   1 
ATOM   4663 C CB  . PHE B 1 36  ? -4.76447  22.09906  -4.77831  1.000 55.38956  ? 35  PHE B CB  1 
ATOM   4664 C CG  . PHE B 1 36  ? -5.32284  20.71189  -4.75130  1.000 56.59375  ? 35  PHE B CG  1 
ATOM   4665 C CD1 . PHE B 1 36  ? -5.64295  20.05863  -5.92858  1.000 58.28750  ? 35  PHE B CD1 1 
ATOM   4666 C CD2 . PHE B 1 36  ? -5.52244  20.05509  -3.55396  1.000 55.50501  ? 35  PHE B CD2 1 
ATOM   4667 C CE1 . PHE B 1 36  ? -6.14459  18.77659  -5.91124  1.000 54.48473  ? 35  PHE B CE1 1 
ATOM   4668 C CE2 . PHE B 1 36  ? -6.02026  18.77679  -3.53349  1.000 55.74523  ? 35  PHE B CE2 1 
ATOM   4669 C CZ  . PHE B 1 36  ? -6.33181  18.13533  -4.71542  1.000 54.62942  ? 35  PHE B CZ  1 
ATOM   4670 N N   . CYS B 1 37  ? -2.77839  24.45041  -6.05088  1.000 54.28102  ? 36  CYS B N   1 
ATOM   4671 C CA  . CYS B 1 37  ? -2.42990  25.85446  -6.24618  1.000 58.18279  ? 36  CYS B CA  1 
ATOM   4672 C C   . CYS B 1 37  ? -2.61389  26.25090  -7.69987  1.000 59.60200  ? 36  CYS B C   1 
ATOM   4673 O O   . CYS B 1 37  ? -3.19015  27.30484  -7.99775  1.000 60.07631  ? 36  CYS B O   1 
ATOM   4674 C CB  . CYS B 1 37  ? -0.99240  26.11797  -5.80497  1.000 60.00932  ? 36  CYS B CB  1 
ATOM   4675 S SG  . CYS B 1 37  ? -0.75551  26.12694  -4.00057  1.000 68.25464  ? 36  CYS B SG  1 
ATOM   4676 N N   . HIS B 1 38  ? -2.15625  25.39377  -8.61502  1.000 58.42415  ? 37  HIS B N   1 
ATOM   4677 C CA  . HIS B 1 38  ? -2.33079  25.64408  -10.03944 1.000 54.49627  ? 37  HIS B CA  1 
ATOM   4678 C C   . HIS B 1 38  ? -3.79771  25.79946  -10.42003 1.000 51.34292  ? 37  HIS B C   1 
ATOM   4679 O O   . HIS B 1 38  ? -4.12358  26.57803  -11.31655 1.000 54.29000  ? 37  HIS B O   1 
ATOM   4680 C CB  . HIS B 1 38  ? -1.68698  24.51691  -10.84208 1.000 53.06493  ? 37  HIS B CB  1 
ATOM   4681 C CG  . HIS B 1 38  ? -1.87668  24.64858  -12.31739 1.000 53.49392  ? 37  HIS B CG  1 
ATOM   4682 N ND1 . HIS B 1 38  ? -0.90345  25.15735  -13.14840 1.000 50.32774  ? 37  HIS B ND1 1 
ATOM   4683 C CD2 . HIS B 1 38  ? -2.93219  24.34826  -13.11051 1.000 53.49751  ? 37  HIS B CD2 1 
ATOM   4684 C CE1 . HIS B 1 38  ? -1.35272  25.16551  -14.39027 1.000 52.39105  ? 37  HIS B CE1 1 
ATOM   4685 N NE2 . HIS B 1 38  ? -2.57962  24.67653  -14.39495 1.000 49.67125  ? 37  HIS B NE2 1 
ATOM   4686 N N   . GLU B 1 39  ? -4.69890  25.08130  -9.76979  1.000 52.40231  ? 38  GLU B N   1 
ATOM   4687 C CA  . GLU B 1 39  ? -6.10581  25.20153  -10.10548 1.000 54.70535  ? 38  GLU B CA  1 
ATOM   4688 C C   . GLU B 1 39  ? -6.82983  26.16859  -9.19665  1.000 58.97910  ? 38  GLU B C   1 
ATOM   4689 O O   . GLU B 1 39  ? -8.06664  26.21161  -9.21963  1.000 63.40302  ? 38  GLU B O   1 
ATOM   4690 C CB  . GLU B 1 39  ? -6.78466  23.84029  -10.05798 1.000 53.61082  ? 38  GLU B CB  1 
ATOM   4691 C CG  . GLU B 1 39  ? -6.10864  22.83609  -10.92220 1.000 54.50058  ? 38  GLU B CG  1 
ATOM   4692 C CD  . GLU B 1 39  ? -6.68193  21.45991  -10.75005 1.000 59.19477  ? 38  GLU B CD  1 
ATOM   4693 O OE1 . GLU B 1 39  ? -7.90028  21.36744  -10.49993 1.000 56.54931  ? 38  GLU B OE1 1 
ATOM   4694 O OE2 . GLU B 1 39  ? -5.91056  20.47704  -10.85903 1.000 61.46992  ? 38  GLU B OE2 1 
ATOM   4695 N N   . ARG B 1 40  ? -6.09171  26.93708  -8.39082  1.000 55.85808  ? 39  ARG B N   1 
ATOM   4696 C CA  . ARG B 1 40  ? -6.66400  27.93036  -7.48159  1.000 58.28759  ? 39  ARG B CA  1 
ATOM   4697 C C   . ARG B 1 40  ? -7.65503  27.30879  -6.50447  1.000 59.70745  ? 39  ARG B C   1 
ATOM   4698 O O   . ARG B 1 40  ? -8.54981  27.99343  -6.00813  1.000 62.29508  ? 39  ARG B O   1 
ATOM   4699 C CB  . ARG B 1 40  ? -7.33797  29.07409  -8.25466  1.000 57.89412  ? 39  ARG B CB  1 
ATOM   4700 C CG  . ARG B 1 40  ? -6.55716  29.58029  -9.47638  1.000 61.54396  ? 39  ARG B CG  1 
ATOM   4701 C CD  . ARG B 1 40  ? -7.20798  30.81976  -10.06747 1.000 60.36874  ? 39  ARG B CD  1 
ATOM   4702 N NE  . ARG B 1 40  ? -6.28824  31.62457  -10.86340 1.000 67.20528  ? 39  ARG B NE  1 
ATOM   4703 C CZ  . ARG B 1 40  ? -6.48773  32.90713  -11.14418 1.000 72.90300  ? 39  ARG B CZ  1 
ATOM   4704 N NH1 . ARG B 1 40  ? -7.56028  33.55172  -10.70617 1.000 75.34167  ? 39  ARG B NH1 1 
ATOM   4705 N NH2 . ARG B 1 40  ? -5.58565  33.56353  -11.87147 1.000 65.18533  ? 39  ARG B NH2 1 
ATOM   4706 N N   . LEU B 1 41  ? -7.54248  25.99977  -6.26963  1.000 60.14313  ? 40  LEU B N   1 
ATOM   4707 C CA  . LEU B 1 41  ? -8.24842  25.35411  -5.17432  1.000 59.20008  ? 40  LEU B CA  1 
ATOM   4708 C C   . LEU B 1 41  ? -7.61925  25.72989  -3.84588  1.000 62.92207  ? 40  LEU B C   1 
ATOM   4709 O O   . LEU B 1 41  ? -8.25730  25.60057  -2.79432  1.000 64.69334  ? 40  LEU B O   1 
ATOM   4710 C CB  . LEU B 1 41  ? -8.20708  23.83382  -5.36597  1.000 62.59857  ? 40  LEU B CB  1 
ATOM   4711 C CG  . LEU B 1 41  ? -9.06221  23.11496  -6.42267  1.000 62.55028  ? 40  LEU B CG  1 
ATOM   4712 C CD1 . LEU B 1 41  ? -8.75822  21.61822  -6.39533  1.000 61.16268  ? 40  LEU B CD1 1 
ATOM   4713 C CD2 . LEU B 1 41  ? -10.55430 23.33147  -6.22128  1.000 55.22402  ? 40  LEU B CD2 1 
ATOM   4714 N N   . VAL B 1 42  ? -6.38274  26.21630  -3.89442  1.000 62.41797  ? 41  VAL B N   1 
ATOM   4715 C CA  . VAL B 1 42  ? -5.53917  26.48572  -2.73718  1.000 64.11793  ? 41  VAL B CA  1 
ATOM   4716 C C   . VAL B 1 42  ? -4.71909  27.72006  -3.07709  1.000 66.78805  ? 41  VAL B C   1 
ATOM   4717 O O   . VAL B 1 42  ? -3.83955  27.67579  -3.94937  1.000 67.02413  ? 41  VAL B O   1 
ATOM   4718 C CB  . VAL B 1 42  ? -4.63013  25.28231  -2.41412  1.000 60.37054  ? 41  VAL B CB  1 
ATOM   4719 C CG1 . VAL B 1 42  ? -3.43293  25.70147  -1.56811  1.000 49.99123  ? 41  VAL B CG1 1 
ATOM   4720 C CG2 . VAL B 1 42  ? -5.43316  24.16850  -1.76208  1.000 57.67605  ? 41  VAL B CG2 1 
ATOM   4721 N N   . ARG B 1 43  ? -5.01785  28.84008  -2.42068  1.000 62.30360  ? 42  ARG B N   1 
ATOM   4722 C CA  . ARG B 1 43  ? -4.35435  30.10296  -2.72478  1.000 56.88816  ? 42  ARG B CA  1 
ATOM   4723 C C   . ARG B 1 43  ? -3.42676  30.49003  -1.57383  1.000 54.39643  ? 42  ARG B C   1 
ATOM   4724 O O   . ARG B 1 43  ? -3.86636  31.11534  -0.60002  1.000 54.56943  ? 42  ARG B O   1 
ATOM   4725 C CB  . ARG B 1 43  ? -5.39824  31.18649  -2.99604  1.000 44.88615  ? 42  ARG B CB  1 
ATOM   4726 N N   . PRO B 1 44  ? -2.13378  30.15009  -1.64021  1.000 56.96673  ? 43  PRO B N   1 
ATOM   4727 C CA  . PRO B 1 44  ? -1.25201  30.31429  -0.47231  1.000 57.46209  ? 43  PRO B CA  1 
ATOM   4728 C C   . PRO B 1 44  ? -0.80983  31.74951  -0.23809  1.000 62.13586  ? 43  PRO B C   1 
ATOM   4729 O O   . PRO B 1 44  ? -0.41119  32.45703  -1.16612  1.000 66.69600  ? 43  PRO B O   1 
ATOM   4730 C CB  . PRO B 1 44  ? -0.03256  29.44768  -0.81551  1.000 57.18554  ? 43  PRO B CB  1 
ATOM   4731 C CG  . PRO B 1 44  ? -0.32874  28.81137  -2.13059  1.000 54.42252  ? 43  PRO B CG  1 
ATOM   4732 C CD  . PRO B 1 44  ? -1.41492  29.57980  -2.78656  1.000 53.15246  ? 43  PRO B CD  1 
ATOM   4733 N N   . THR B 1 45  ? -0.84526  32.15427  1.03437   1.000 68.30634  ? 44  THR B N   1 
ATOM   4734 C CA  . THR B 1 45  ? -0.34073  33.45337  1.46927   1.000 65.27213  ? 44  THR B CA  1 
ATOM   4735 C C   . THR B 1 45  ? 1.17873   33.45240  1.52682   1.000 63.92994  ? 44  THR B C   1 
ATOM   4736 O O   . THR B 1 45  ? 1.79611   32.49332  2.00328   1.000 61.65116  ? 44  THR B O   1 
ATOM   4737 C CB  . THR B 1 45  ? -0.89489  33.80605  2.84366   1.000 63.38024  ? 44  THR B CB  1 
ATOM   4738 O OG1 . THR B 1 45  ? -2.31739  33.68704  2.81941   1.000 67.46432  ? 44  THR B OG1 1 
ATOM   4739 C CG2 . THR B 1 45  ? -0.52035  35.21107  3.19863   1.000 71.27578  ? 44  THR B CG2 1 
ATOM   4740 N N   . GLU B 1 46  ? 1.77919   34.53889  1.04552   1.000 66.34370  ? 45  GLU B N   1 
ATOM   4741 C CA  . GLU B 1 46  ? 3.22474   34.62503  0.86721   1.000 71.45796  ? 45  GLU B CA  1 
ATOM   4742 C C   . GLU B 1 46  ? 3.79968   35.66957  1.80598   1.000 78.73133  ? 45  GLU B C   1 
ATOM   4743 O O   . GLU B 1 46  ? 3.36199   36.82785  1.80768   1.000 77.38558  ? 45  GLU B O   1 
ATOM   4744 C CB  . GLU B 1 46  ? 3.59634   34.96354  -0.57615  1.000 72.64039  ? 45  GLU B CB  1 
ATOM   4745 C CG  . GLU B 1 46  ? 4.91458   35.69383  -0.72507  1.000 74.90510  ? 45  GLU B CG  1 
ATOM   4746 C CD  . GLU B 1 46  ? 5.12423   36.21533  -2.13483  1.000 81.47825  ? 45  GLU B CD  1 
ATOM   4747 O OE1 . GLU B 1 46  ? 4.56751   37.28995  -2.46439  1.000 80.03122  ? 45  GLU B OE1 1 
ATOM   4748 O OE2 . GLU B 1 46  ? 5.86055   35.55670  -2.90630  1.000 83.57844  ? 45  GLU B OE2 1 
ATOM   4749 N N   . LEU B 1 47  ? 4.78958   35.25036  2.58770   1.000 80.38097  ? 46  LEU B N   1 
ATOM   4750 C CA  . LEU B 1 47  ? 5.33941   36.05374  3.66803   1.000 75.00386  ? 46  LEU B CA  1 
ATOM   4751 C C   . LEU B 1 47  ? 6.58581   36.76696  3.15822   1.000 79.16141  ? 46  LEU B C   1 
ATOM   4752 O O   . LEU B 1 47  ? 6.48446   37.81535  2.50910   1.000 80.92346  ? 46  LEU B O   1 
ATOM   4753 C CB  . LEU B 1 47  ? 5.61626   35.15034  4.87548   1.000 70.61518  ? 46  LEU B CB  1 
ATOM   4754 C CG  . LEU B 1 47  ? 4.57932   34.01377  5.04923   1.000 68.93893  ? 46  LEU B CG  1 
ATOM   4755 C CD1 . LEU B 1 47  ? 4.97702   32.99619  6.11167   1.000 46.59114  ? 46  LEU B CD1 1 
ATOM   4756 C CD2 . LEU B 1 47  ? 3.15107   34.54423  5.31806   1.000 64.94064  ? 46  LEU B CD2 1 
ATOM   4757 N N   . SER B 1 48  ? 7.76031   36.20660  3.43170   1.000 81.37539  ? 47  SER B N   1 
ATOM   4758 C CA  . SER B 1 48  ? 8.94626   36.61277  2.70056   1.000 76.98193  ? 47  SER B CA  1 
ATOM   4759 C C   . SER B 1 48  ? 8.74134   36.27461  1.22617   1.000 79.84537  ? 47  SER B C   1 
ATOM   4760 O O   . SER B 1 48  ? 8.07656   35.28545  0.89796   1.000 79.15858  ? 47  SER B O   1 
ATOM   4761 C CB  . SER B 1 48  ? 10.17687  35.88688  3.23159   1.000 74.98271  ? 47  SER B CB  1 
ATOM   4762 O OG  . SER B 1 48  ? 10.03525  35.62438  4.61881   1.000 78.05202  ? 47  SER B OG  1 
ATOM   4763 N N   . PRO B 1 49  ? 9.27946   37.07827  0.31387   1.000 87.38200  ? 48  PRO B N   1 
ATOM   4764 C CA  . PRO B 1 49  ? 9.12768   36.75342  -1.10823  1.000 84.48957  ? 48  PRO B CA  1 
ATOM   4765 C C   . PRO B 1 49  ? 9.65538   35.35367  -1.39312  1.000 82.67934  ? 48  PRO B C   1 
ATOM   4766 O O   . PRO B 1 49  ? 10.75062  34.98180  -0.96140  1.000 77.59304  ? 48  PRO B O   1 
ATOM   4767 C CB  . PRO B 1 49  ? 9.95318   37.84689  -1.80008  1.000 78.35602  ? 48  PRO B CB  1 
ATOM   4768 C CG  . PRO B 1 49  ? 11.01577  38.15449  -0.77730  1.000 78.95987  ? 48  PRO B CG  1 
ATOM   4769 C CD  . PRO B 1 49  ? 10.18571  38.22798  0.48912   1.000 90.19373  ? 48  PRO B CD  1 
ATOM   4770 N N   . GLY B 1 50  ? 8.84824   34.56446  -2.09935  1.000 77.01436  ? 49  GLY B N   1 
ATOM   4771 C CA  . GLY B 1 50  ? 9.24287   33.20342  -2.39287  1.000 72.40924  ? 49  GLY B CA  1 
ATOM   4772 C C   . GLY B 1 50  ? 9.13238   32.24351  -1.23421  1.000 74.12336  ? 49  GLY B C   1 
ATOM   4773 O O   . GLY B 1 50  ? 9.62398   31.11705  -1.33871  1.000 71.32997  ? 49  GLY B O   1 
ATOM   4774 N N   . ARG B 1 51  ? 8.51604   32.65179  -0.12459  1.000 75.90659  ? 50  ARG B N   1 
ATOM   4775 C CA  . ARG B 1 51  ? 8.27826   31.76679  1.01002   1.000 68.54095  ? 50  ARG B CA  1 
ATOM   4776 C C   . ARG B 1 51  ? 6.82632   31.95286  1.42270   1.000 66.77112  ? 50  ARG B C   1 
ATOM   4777 O O   . ARG B 1 51  ? 6.38530   33.08200  1.66272   1.000 65.47378  ? 50  ARG B O   1 
ATOM   4778 C CB  . ARG B 1 51  ? 9.25246   32.05664  2.16407   1.000 66.21480  ? 50  ARG B CB  1 
ATOM   4779 C CG  . ARG B 1 51  ? 10.70711  31.72587  1.77874   1.000 71.08123  ? 50  ARG B CG  1 
ATOM   4780 C CD  . ARG B 1 51  ? 11.46144  30.77063  2.71812   1.000 80.33114  ? 50  ARG B CD  1 
ATOM   4781 N NE  . ARG B 1 51  ? 11.29932  31.06299  4.14030   1.000 95.52892  ? 50  ARG B NE  1 
ATOM   4782 C CZ  . ARG B 1 51  ? 12.03070  30.51921  5.10982   1.000 91.63988  ? 50  ARG B CZ  1 
ATOM   4783 N NH1 . ARG B 1 51  ? 13.02247  29.67843  4.84286   1.000 78.42312  ? 50  ARG B NH1 1 
ATOM   4784 N NH2 . ARG B 1 51  ? 11.76465  30.83181  6.37903   1.000 78.82742  ? 50  ARG B NH2 1 
ATOM   4785 N N   . TYR B 1 52  ? 6.07634   30.85313  1.46037   1.000 65.88114  ? 51  TYR B N   1 
ATOM   4786 C CA  . TYR B 1 52  ? 4.62560   30.88978  1.57792   1.000 65.69315  ? 51  TYR B CA  1 
ATOM   4787 C C   . TYR B 1 52  ? 4.17664   30.03334  2.75321   1.000 64.71072  ? 51  TYR B C   1 
ATOM   4788 O O   . TYR B 1 52  ? 4.93283   29.21891  3.29033   1.000 65.27734  ? 51  TYR B O   1 
ATOM   4789 C CB  . TYR B 1 52  ? 3.93810   30.38461  0.29357   1.000 64.43152  ? 51  TYR B CB  1 
ATOM   4790 C CG  . TYR B 1 52  ? 4.48129   30.94500  -1.01189  1.000 64.66279  ? 51  TYR B CG  1 
ATOM   4791 C CD1 . TYR B 1 52  ? 5.73177   30.55538  -1.50328  1.000 65.75999  ? 51  TYR B CD1 1 
ATOM   4792 C CD2 . TYR B 1 52  ? 3.72782   31.83961  -1.76934  1.000 60.62430  ? 51  TYR B CD2 1 
ATOM   4793 C CE1 . TYR B 1 52  ? 6.22660   31.06329  -2.69426  1.000 69.68449  ? 51  TYR B CE1 1 
ATOM   4794 C CE2 . TYR B 1 52  ? 4.21379   32.35848  -2.96249  1.000 68.78096  ? 51  TYR B CE2 1 
ATOM   4795 C CZ  . TYR B 1 52  ? 5.46344   31.96525  -3.42249  1.000 74.30258  ? 51  TYR B CZ  1 
ATOM   4796 O OH  . TYR B 1 52  ? 5.94668   32.47522  -4.60974  1.000 67.85552  ? 51  TYR B OH  1 
ATOM   4797 N N   . VAL B 1 53  ? 2.91251   30.19890  3.12899   1.000 62.53384  ? 52  VAL B N   1 
ATOM   4798 C CA  . VAL B 1 53  ? 2.28157   29.32385  4.10589   1.000 62.13696  ? 52  VAL B CA  1 
ATOM   4799 C C   . VAL B 1 53  ? 0.88732   28.97324  3.60186   1.000 60.88863  ? 52  VAL B C   1 
ATOM   4800 O O   . VAL B 1 53  ? 0.25097   29.75004  2.88393   1.000 61.28327  ? 52  VAL B O   1 
ATOM   4801 C CB  . VAL B 1 53  ? 2.20776   29.96996  5.51382   1.000 66.31841  ? 52  VAL B CB  1 
ATOM   4802 C CG1 . VAL B 1 53  ? 0.98366   30.89520  5.64518   1.000 65.52679  ? 52  VAL B CG1 1 
ATOM   4803 C CG2 . VAL B 1 53  ? 2.20564   28.90619  6.59877   1.000 64.69117  ? 52  VAL B CG2 1 
ATOM   4804 N N   . VAL B 1 54  ? 0.41622   27.78663  3.96929   1.000 58.61111  ? 53  VAL B N   1 
ATOM   4805 C CA  . VAL B 1 54  ? -0.96547  27.39237  3.73032   1.000 61.43357  ? 53  VAL B CA  1 
ATOM   4806 C C   . VAL B 1 54  ? -1.56235  26.98715  5.07077   1.000 58.87650  ? 53  VAL B C   1 
ATOM   4807 O O   . VAL B 1 54  ? -0.90443  26.30552  5.86872   1.000 55.31479  ? 53  VAL B O   1 
ATOM   4808 C CB  . VAL B 1 54  ? -1.08837  26.24170  2.70107   1.000 59.36860  ? 53  VAL B CB  1 
ATOM   4809 C CG1 . VAL B 1 54  ? -2.53135  25.74701  2.63839   1.000 52.25118  ? 53  VAL B CG1 1 
ATOM   4810 C CG2 . VAL B 1 54  ? -0.60309  26.67519  1.31076   1.000 53.05940  ? 53  VAL B CG2 1 
ATOM   4811 N N   . HIS B 1 55  ? -2.80504  27.41240  5.31393   1.000 49.50701  ? 54  HIS B N   1 
ATOM   4812 C CA  . HIS B 1 55  ? -3.49224  27.19498  6.57716   1.000 50.72555  ? 54  HIS B CA  1 
ATOM   4813 C C   . HIS B 1 55  ? -4.51377  26.08803  6.43160   1.000 59.81637  ? 54  HIS B C   1 
ATOM   4814 O O   . HIS B 1 55  ? -5.37227  26.14827  5.54690   1.000 67.73579  ? 54  HIS B O   1 
ATOM   4815 C CB  . HIS B 1 55  ? -4.21963  28.45332  7.04439   1.000 61.78859  ? 54  HIS B CB  1 
ATOM   4816 C CG  . HIS B 1 55  ? -3.31027  29.53769  7.50914   1.000 64.32060  ? 54  HIS B CG  1 
ATOM   4817 N ND1 . HIS B 1 55  ? -2.27109  29.30937  8.38423   1.000 68.02706  ? 54  HIS B ND1 1 
ATOM   4818 C CD2 . HIS B 1 55  ? -3.27973  30.85842  7.21874   1.000 64.24460  ? 54  HIS B CD2 1 
ATOM   4819 C CE1 . HIS B 1 55  ? -1.63643  30.44454  8.60978   1.000 72.04516  ? 54  HIS B CE1 1 
ATOM   4820 N NE2 . HIS B 1 55  ? -2.22818  31.39911  7.91395   1.000 70.90524  ? 54  HIS B NE2 1 
ATOM   4821 N N   . SER B 1 56  ? -4.45542  25.11043  7.32805   1.000 62.24296  ? 55  SER B N   1 
ATOM   4822 C CA  . SER B 1 56  ? -5.51015  24.11520  7.38242   1.000 64.86704  ? 55  SER B CA  1 
ATOM   4823 C C   . SER B 1 56  ? -6.84813  24.79325  7.64214   1.000 65.23074  ? 55  SER B C   1 
ATOM   4824 O O   . SER B 1 56  ? -6.91682  25.93514  8.09818   1.000 66.00755  ? 55  SER B O   1 
ATOM   4825 C CB  . SER B 1 56  ? -5.22476  23.09274  8.47475   1.000 66.16298  ? 55  SER B CB  1 
ATOM   4826 O OG  . SER B 1 56  ? -5.34818  23.68655  9.75490   1.000 70.71663  ? 55  SER B OG  1 
ATOM   4827 N N   . ASP B 1 57  ? -7.92105  24.07770  7.33074   1.000 63.30395  ? 56  ASP B N   1 
ATOM   4828 C CA  . ASP B 1 57  ? -9.25624  24.61069  7.53771   1.000 64.52618  ? 56  ASP B CA  1 
ATOM   4829 C C   . ASP B 1 57  ? -9.42550  25.10711  8.96549   1.000 68.32045  ? 56  ASP B C   1 
ATOM   4830 O O   . ASP B 1 57  ? -9.55142  26.31382  9.19281   1.000 69.88499  ? 56  ASP B O   1 
ATOM   4831 C CB  . ASP B 1 57  ? -10.30474 23.55176  7.21326   1.000 73.84947  ? 56  ASP B CB  1 
ATOM   4832 C CG  . ASP B 1 57  ? -10.54271 23.41137  5.72036   1.000 77.19402  ? 56  ASP B CG  1 
ATOM   4833 O OD1 . ASP B 1 57  ? -9.92480  24.18939  4.95451   1.000 76.95567  ? 56  ASP B OD1 1 
ATOM   4834 O OD2 . ASP B 1 57  ? -11.34362 22.52838  5.31669   1.000 72.79862  ? 56  ASP B OD2 1 
ATOM   4835 N N   . ASP B 1 58  ? -9.38723  24.19695  9.93733   1.000 71.24723  ? 57  ASP B N   1 
ATOM   4836 C CA  . ASP B 1 58  ? -9.60261  24.58509  11.33479  1.000 69.21816  ? 57  ASP B CA  1 
ATOM   4837 C C   . ASP B 1 58  ? -8.49285  25.49198  11.90106  1.000 70.98300  ? 57  ASP B C   1 
ATOM   4838 O O   . ASP B 1 58  ? -8.48315  25.74937  13.10715  1.000 73.78883  ? 57  ASP B O   1 
ATOM   4839 C CB  . ASP B 1 58  ? -9.77131  23.33927  12.21074  1.000 63.76768  ? 57  ASP B CB  1 
ATOM   4840 C CG  . ASP B 1 58  ? -8.59009  22.38830  12.14042  1.000 69.29020  ? 57  ASP B CG  1 
ATOM   4841 O OD1 . ASP B 1 58  ? -7.51252  22.76860  11.62689  1.000 70.45000  ? 57  ASP B OD1 1 
ATOM   4842 O OD2 . ASP B 1 58  ? -8.75986  21.23368  12.59933  1.000 79.12124  ? 57  ASP B OD2 1 
ATOM   4843 N N   . ARG B 1 59  ? -7.57403  25.96813  11.06621  1.000 72.02008  ? 58  ARG B N   1 
ATOM   4844 C CA  . ARG B 1 59  ? -6.52093  26.91394  11.42233  1.000 67.71340  ? 58  ARG B CA  1 
ATOM   4845 C C   . ARG B 1 59  ? -5.60102  26.39361  12.52480  1.000 64.50468  ? 58  ARG B C   1 
ATOM   4846 O O   . ARG B 1 59  ? -4.76016  27.14969  13.03535  1.000 65.45963  ? 58  ARG B O   1 
ATOM   4847 C CB  . ARG B 1 59  ? -7.11698  28.27505  11.79798  1.000 62.32308  ? 58  ARG B CB  1 
ATOM   4848 C CG  . ARG B 1 59  ? -8.22868  28.74183  10.84648  1.000 58.70682  ? 58  ARG B CG  1 
ATOM   4849 C CD  . ARG B 1 59  ? -7.65520  29.42555  9.62001   1.000 72.04570  ? 58  ARG B CD  1 
ATOM   4850 N NE  . ARG B 1 59  ? -6.40492  30.11495  9.92467   1.000 77.83468  ? 58  ARG B NE  1 
ATOM   4851 C CZ  . ARG B 1 59  ? -5.96934  31.20173  9.29640   1.000 81.00405  ? 58  ARG B CZ  1 
ATOM   4852 N NH1 . ARG B 1 59  ? -6.65694  31.75403  8.30780   1.000 79.55532  ? 58  ARG B NH1 1 
ATOM   4853 N NH2 . ARG B 1 59  ? -4.81884  31.75499  9.67576   1.000 76.73280  ? 58  ARG B NH2 1 
ATOM   4854 N N   . GLU B 1 60  ? -5.71218  25.11078  12.87860  1.000 61.07613  ? 59  GLU B N   1 
ATOM   4855 C CA  . GLU B 1 60  ? -4.81478  24.48263  13.83647  1.000 63.96682  ? 59  GLU B CA  1 
ATOM   4856 C C   . GLU B 1 60  ? -3.55559  23.90730  13.19071  1.000 66.24217  ? 59  GLU B C   1 
ATOM   4857 O O   . GLU B 1 60  ? -2.60156  23.58413  13.90595  1.000 68.19661  ? 59  GLU B O   1 
ATOM   4858 C CB  . GLU B 1 60  ? -5.55115  23.37875  14.61431  1.000 57.26102  ? 59  GLU B CB  1 
ATOM   4859 N N   . THR B 1 61  ? -3.51167  23.76743  11.87250  1.000 62.86730  ? 60  THR B N   1 
ATOM   4860 C CA  . THR B 1 61  ? -2.30865  23.28602  11.21193  1.000 66.38711  ? 60  THR B CA  1 
ATOM   4861 C C   . THR B 1 61  ? -1.80729  24.34096  10.23282  1.000 69.82649  ? 60  THR B C   1 
ATOM   4862 O O   . THR B 1 61  ? -2.58020  25.16094  9.71962   1.000 65.66604  ? 60  THR B O   1 
ATOM   4863 C CB  . THR B 1 61  ? -2.54591  21.95932  10.48173  1.000 63.52934  ? 60  THR B CB  1 
ATOM   4864 O OG1 . THR B 1 61  ? -3.49744  21.17169  11.20708  1.000 62.25347  ? 60  THR B OG1 1 
ATOM   4865 C CG2 . THR B 1 61  ? -1.25383  21.18400  10.37630  1.000 62.81867  ? 60  THR B CG2 1 
ATOM   4866 N N   . GLU B 1 62  ? -0.49605  24.32905  9.99945   1.000 63.41533  ? 61  GLU B N   1 
ATOM   4867 C CA  . GLU B 1 62  ? 0.15434   25.33868  9.17690   1.000 59.12191  ? 61  GLU B CA  1 
ATOM   4868 C C   . GLU B 1 62  ? 1.13877   24.62898  8.26455   1.000 65.69962  ? 61  GLU B C   1 
ATOM   4869 O O   . GLU B 1 62  ? 2.05196   23.94709  8.74821   1.000 61.16857  ? 61  GLU B O   1 
ATOM   4870 C CB  . GLU B 1 62  ? 0.86692   26.38115  10.04056  1.000 63.14686  ? 61  GLU B CB  1 
ATOM   4871 C CG  . GLU B 1 62  ? 0.64215   27.82652  9.60894   1.000 71.76872  ? 61  GLU B CG  1 
ATOM   4872 C CD  . GLU B 1 62  ? 1.29714   28.85013  10.54858  1.000 79.24560  ? 61  GLU B CD  1 
ATOM   4873 O OE1 . GLU B 1 62  ? 0.56461   29.53024  11.31284  1.000 75.72845  ? 61  GLU B OE1 1 
ATOM   4874 O OE2 . GLU B 1 62  ? 2.54484   28.97874  10.51340  1.000 72.80903  ? 61  GLU B OE2 1 
ATOM   4875 N N   . TYR B 1 63  ? 0.93015   24.75779  6.95051   1.000 60.59882  ? 62  TYR B N   1 
ATOM   4876 C CA  . TYR B 1 63  ? 1.83063   24.18822  5.95805   1.000 57.18698  ? 62  TYR B CA  1 
ATOM   4877 C C   . TYR B 1 63  ? 2.67636   25.32774  5.41773   1.000 62.81268  ? 62  TYR B C   1 
ATOM   4878 O O   . TYR B 1 63  ? 2.14079   26.28354  4.84297   1.000 66.49834  ? 62  TYR B O   1 
ATOM   4879 C CB  . TYR B 1 63  ? 1.06283   23.47483  4.84301   1.000 50.99329  ? 62  TYR B CB  1 
ATOM   4880 C CG  . TYR B 1 63  ? 0.40790   22.22867  5.34753   1.000 46.75496  ? 62  TYR B CG  1 
ATOM   4881 C CD1 . TYR B 1 63  ? 1.12181   21.04416  5.46549   1.000 45.93368  ? 62  TYR B CD1 1 
ATOM   4882 C CD2 . TYR B 1 63  ? -0.91242  22.25174  5.77209   1.000 47.32260  ? 62  TYR B CD2 1 
ATOM   4883 C CE1 . TYR B 1 63  ? 0.52407   19.90793  5.96949   1.000 48.46582  ? 62  TYR B CE1 1 
ATOM   4884 C CE2 . TYR B 1 63  ? -1.51323  21.13181  6.28096   1.000 51.33618  ? 62  TYR B CE2 1 
ATOM   4885 C CZ  . TYR B 1 63  ? -0.79667  19.96265  6.38585   1.000 54.21736  ? 62  TYR B CZ  1 
ATOM   4886 O OH  . TYR B 1 63  ? -1.41885  18.84551  6.89959   1.000 59.20455  ? 62  TYR B OH  1 
ATOM   4887 N N   . ARG B 1 64  ? 3.98494   25.24619  5.63752   1.000 53.38461  ? 63  ARG B N   1 
ATOM   4888 C CA  . ARG B 1 64  ? 4.88155   26.34253  5.31691   1.000 59.82811  ? 63  ARG B CA  1 
ATOM   4889 C C   . ARG B 1 64  ? 5.97142   25.79530  4.41963   1.000 61.07396  ? 63  ARG B C   1 
ATOM   4890 O O   . ARG B 1 64  ? 6.59769   24.77776  4.74634   1.000 61.81610  ? 63  ARG B O   1 
ATOM   4891 C CB  . ARG B 1 64  ? 5.47404   26.99125  6.58424   1.000 53.70598  ? 63  ARG B CB  1 
ATOM   4892 N N   . PHE B 1 65  ? 6.17413   26.46305  3.28464   1.000 55.72216  ? 64  PHE B N   1 
ATOM   4893 C CA  . PHE B 1 65  ? 7.11243   26.01053  2.26798   1.000 60.88563  ? 64  PHE B CA  1 
ATOM   4894 C C   . PHE B 1 65  ? 7.58114   27.20917  1.45741   1.000 65.55144  ? 64  PHE B C   1 
ATOM   4895 O O   . PHE B 1 65  ? 6.96567   28.28249  1.47870   1.000 61.49638  ? 64  PHE B O   1 
ATOM   4896 C CB  . PHE B 1 65  ? 6.47302   24.97454  1.33589   1.000 62.37112  ? 64  PHE B CB  1 
ATOM   4897 C CG  . PHE B 1 65  ? 5.23205   25.47700  0.65392   1.000 62.62165  ? 64  PHE B CG  1 
ATOM   4898 C CD1 . PHE B 1 65  ? 3.98510   25.33619  1.26623   1.000 57.53289  ? 64  PHE B CD1 1 
ATOM   4899 C CD2 . PHE B 1 65  ? 5.31138   26.11830  -0.58233  1.000 58.72963  ? 64  PHE B CD2 1 
ATOM   4900 C CE1 . PHE B 1 65  ? 2.83493   25.80984  0.65894   1.000 58.31980  ? 64  PHE B CE1 1 
ATOM   4901 C CE2 . PHE B 1 65  ? 4.16848   26.59727  -1.20133  1.000 58.62558  ? 64  PHE B CE2 1 
ATOM   4902 C CZ  . PHE B 1 65  ? 2.92305   26.44564  -0.57941  1.000 62.19736  ? 64  PHE B CZ  1 
ATOM   4903 N N   . ARG B 1 66  ? 8.67390   27.01341  0.72790   1.000 59.05903  ? 65  ARG B N   1 
ATOM   4904 C CA  . ARG B 1 66  ? 9.13667   28.00292  -0.23054  1.000 67.06008  ? 65  ARG B CA  1 
ATOM   4905 C C   . ARG B 1 66  ? 8.93059   27.46251  -1.64457  1.000 73.28496  ? 65  ARG B C   1 
ATOM   4906 O O   . ARG B 1 66  ? 9.36024   26.34616  -1.97130  1.000 69.35066  ? 65  ARG B O   1 
ATOM   4907 C CB  . ARG B 1 66  ? 10.59830  28.39231  0.02927   1.000 67.25873  ? 65  ARG B CB  1 
ATOM   4908 C CG  . ARG B 1 66  ? 11.59689  27.25178  0.04074   1.000 69.20707  ? 65  ARG B CG  1 
ATOM   4909 C CD  . ARG B 1 66  ? 13.01443  27.77241  -0.17096  1.000 70.31570  ? 65  ARG B CD  1 
ATOM   4910 N NE  . ARG B 1 66  ? 13.76907  26.96760  -1.12925  1.000 73.39612  ? 65  ARG B NE  1 
ATOM   4911 C CZ  . ARG B 1 66  ? 13.59695  27.00233  -2.44853  1.000 83.88487  ? 65  ARG B CZ  1 
ATOM   4912 N NH1 . ARG B 1 66  ? 12.62882  27.72351  -3.00724  1.000 74.33127  ? 65  ARG B NH1 1 
ATOM   4913 N NH2 . ARG B 1 66  ? 14.41438  26.29389  -3.22934  1.000 76.09312  ? 65  ARG B NH2 1 
ATOM   4914 N N   . ALA B 1 67  ? 8.24639   28.24512  -2.46894  1.000 68.27517  ? 66  ALA B N   1 
ATOM   4915 C CA  . ALA B 1 67  ? 7.93282   27.85639  -3.82999  1.000 67.86823  ? 66  ALA B CA  1 
ATOM   4916 C C   . ALA B 1 67  ? 8.62077   28.79285  -4.81723  1.000 68.17110  ? 66  ALA B C   1 
ATOM   4917 O O   . ALA B 1 67  ? 9.17012   29.83464  -4.44996  1.000 69.80628  ? 66  ALA B O   1 
ATOM   4918 C CB  . ALA B 1 67  ? 6.41510   27.85537  -4.05509  1.000 66.70000  ? 66  ALA B CB  1 
ATOM   4919 N N   . GLU B 1 68  ? 8.57399   28.40040  -6.09039  1.000 65.24747  ? 67  GLU B N   1 
ATOM   4920 C CA  . GLU B 1 68  ? 9.04889   29.21289  -7.20879  1.000 57.05757  ? 67  GLU B CA  1 
ATOM   4921 C C   . GLU B 1 68  ? 8.01510   29.09941  -8.31890  1.000 53.96235  ? 67  GLU B C   1 
ATOM   4922 O O   . GLU B 1 68  ? 7.75489   27.99190  -8.79557  1.000 59.63360  ? 67  GLU B O   1 
ATOM   4923 C CB  . GLU B 1 68  ? 10.42580  28.73247  -7.68817  1.000 48.07803  ? 67  GLU B CB  1 
ATOM   4924 C CG  . GLU B 1 68  ? 10.94890  29.40527  -8.94311  1.000 53.14326  ? 67  GLU B CG  1 
ATOM   4925 C CD  . GLU B 1 68  ? 12.36953  28.95577  -9.30360  1.000 70.49668  ? 67  GLU B CD  1 
ATOM   4926 O OE1 . GLU B 1 68  ? 12.91247  28.06857  -8.59294  1.000 70.13032  ? 67  GLU B OE1 1 
ATOM   4927 O OE2 . GLU B 1 68  ? 12.94045  29.49123  -10.29299 1.000 63.04158  ? 67  GLU B OE2 1 
ATOM   4928 N N   . ILE B 1 69  ? 7.42074   30.21682  -8.73403  1.000 50.57272  ? 68  ILE B N   1 
ATOM   4929 C CA  . ILE B 1 69  ? 6.31929   30.18017  -9.69748  1.000 50.30739  ? 68  ILE B CA  1 
ATOM   4930 C C   . ILE B 1 69  ? 6.87697   30.26639  -11.11403 1.000 55.67830  ? 68  ILE B C   1 
ATOM   4931 O O   . ILE B 1 69  ? 7.56622   31.22908  -11.46579 1.000 57.75106  ? 68  ILE B O   1 
ATOM   4932 C CB  . ILE B 1 69  ? 5.30453   31.29882  -9.44367  1.000 49.33802  ? 68  ILE B CB  1 
ATOM   4933 C CG1 . ILE B 1 69  ? 4.30070   30.88683  -8.37170  1.000 56.58583  ? 68  ILE B CG1 1 
ATOM   4934 C CG2 . ILE B 1 69  ? 4.54339   31.60666  -10.71442 1.000 46.92240  ? 68  ILE B CG2 1 
ATOM   4935 C CD1 . ILE B 1 69  ? 4.89906   30.21390  -7.18157  1.000 60.41404  ? 68  ILE B CD1 1 
ATOM   4936 N N   . LEU B 1 70  ? 6.56353   29.26596  -11.93438 1.000 59.20712  ? 69  LEU B N   1 
ATOM   4937 C CA  . LEU B 1 70  ? 7.08643   29.14339  -13.28607 1.000 52.36932  ? 69  LEU B CA  1 
ATOM   4938 C C   . LEU B 1 70  ? 5.98847   29.39984  -14.31420 1.000 52.59467  ? 69  LEU B C   1 
ATOM   4939 O O   . LEU B 1 70  ? 4.82703   29.69622  -13.98593 1.000 45.06246  ? 69  LEU B O   1 
ATOM   4940 C CB  . LEU B 1 70  ? 7.70407   27.76075  -13.49950 1.000 53.39210  ? 69  LEU B CB  1 
ATOM   4941 C CG  . LEU B 1 70  ? 8.64999   27.24463  -12.42024 1.000 53.16593  ? 69  LEU B CG  1 
ATOM   4942 C CD1 . LEU B 1 70  ? 9.14542   25.84668  -12.75141 1.000 49.93057  ? 69  LEU B CD1 1 
ATOM   4943 C CD2 . LEU B 1 70  ? 9.79397   28.21164  -12.30020 1.000 51.59629  ? 69  LEU B CD2 1 
ATOM   4944 N N   . SER B 1 71  ? 6.37845   29.25912  -15.58078 1.000 53.51756  ? 70  SER B N   1 
ATOM   4945 C CA  . SER B 1 71  ? 5.45614   29.49746  -16.67603 1.000 50.82153  ? 70  SER B CA  1 
ATOM   4946 C C   . SER B 1 71  ? 4.25836   28.56828  -16.56747 1.000 51.83513  ? 70  SER B C   1 
ATOM   4947 O O   . SER B 1 71  ? 4.38521   27.39197  -16.21102 1.000 47.92436  ? 70  SER B O   1 
ATOM   4948 C CB  . SER B 1 71  ? 6.16471   29.30588  -18.00463 1.000 55.05303  ? 70  SER B CB  1 
ATOM   4949 O OG  . SER B 1 71  ? 7.42252   29.95727  -17.96814 1.000 56.92594  ? 70  SER B OG  1 
ATOM   4950 N N   . LEU B 1 72  ? 3.08861   29.13523  -16.83999 1.000 54.37985  ? 71  LEU B N   1 
ATOM   4951 C CA  . LEU B 1 72  ? 1.81653   28.43354  -16.79006 1.000 47.41575  ? 71  LEU B CA  1 
ATOM   4952 C C   . LEU B 1 72  ? 1.39270   28.16592  -15.35555 1.000 46.72524  ? 71  LEU B C   1 
ATOM   4953 O O   . LEU B 1 72  ? 0.93390   27.07274  -15.04122 1.000 53.98670  ? 71  LEU B O   1 
ATOM   4954 C CB  . LEU B 1 72  ? 1.85880   27.13720  -17.59984 1.000 46.81972  ? 71  LEU B CB  1 
ATOM   4955 C CG  . LEU B 1 72  ? 1.93007   27.36293  -19.10506 1.000 47.94902  ? 71  LEU B CG  1 
ATOM   4956 C CD1 . LEU B 1 72  ? 2.37222   26.08629  -19.81894 1.000 49.40229  ? 71  LEU B CD1 1 
ATOM   4957 C CD2 . LEU B 1 72  ? 0.57781   27.86111  -19.61067 1.000 45.73767  ? 71  LEU B CD2 1 
ATOM   4958 N N   . ASP B 1 73  ? 1.52718   29.17321  -14.48668 1.000 52.14924  ? 72  ASP B N   1 
ATOM   4959 C CA  . ASP B 1 73  ? 1.07997   29.08207  -13.08784 1.000 49.15510  ? 72  ASP B CA  1 
ATOM   4960 C C   . ASP B 1 73  ? 1.63511   27.82884  -12.42102 1.000 51.84333  ? 72  ASP B C   1 
ATOM   4961 O O   . ASP B 1 73  ? 0.90754   27.07867  -11.76440 1.000 50.55673  ? 72  ASP B O   1 
ATOM   4962 C CB  . ASP B 1 73  ? -0.45027  29.07333  -12.96765 1.000 47.83349  ? 72  ASP B CB  1 
ATOM   4963 C CG  . ASP B 1 73  ? -1.09134  30.42588  -13.21049 1.000 53.10594  ? 72  ASP B CG  1 
ATOM   4964 O OD1 . ASP B 1 73  ? -0.40117  31.35869  -13.67981 1.000 58.97875  ? 72  ASP B OD1 1 
ATOM   4965 O OD2 . ASP B 1 73  ? -2.30939  30.54163  -12.92840 1.000 52.20627  ? 72  ASP B OD2 1 
ATOM   4966 N N   . SER B 1 74  ? 2.92841   27.58033  -12.61762 1.000 47.87946  ? 73  SER B N   1 
ATOM   4967 C CA  . SER B 1 74  ? 3.52894   26.30684  -12.23812 1.000 45.04993  ? 73  SER B CA  1 
ATOM   4968 C C   . SER B 1 74  ? 4.30862   26.47630  -10.93831 1.000 54.43671  ? 73  SER B C   1 
ATOM   4969 O O   . SER B 1 74  ? 5.44958   26.94429  -10.95618 1.000 59.34809  ? 73  SER B O   1 
ATOM   4970 C CB  . SER B 1 74  ? 4.42459   25.79895  -13.35707 1.000 46.71596  ? 73  SER B CB  1 
ATOM   4971 O OG  . SER B 1 74  ? 4.80109   24.45833  -13.11098 1.000 55.37044  ? 73  SER B OG  1 
ATOM   4972 N N   . TRP B 1 75  ? 3.70884   26.05822  -9.81298  1.000 47.99082  ? 74  TRP B N   1 
ATOM   4973 C CA  . TRP B 1 75  ? 4.33650   26.16867  -8.49286  1.000 47.12457  ? 74  TRP B CA  1 
ATOM   4974 C C   . TRP B 1 75  ? 5.38554   25.06993  -8.31330  1.000 46.63281  ? 74  TRP B C   1 
ATOM   4975 O O   . TRP B 1 75  ? 5.04410   23.90545  -8.09468  1.000 46.32639  ? 74  TRP B O   1 
ATOM   4976 C CB  . TRP B 1 75  ? 3.29230   26.06946  -7.38531  1.000 50.29934  ? 74  TRP B CB  1 
ATOM   4977 C CG  . TRP B 1 75  ? 2.31347   27.19335  -7.30949  1.000 55.82385  ? 74  TRP B CG  1 
ATOM   4978 C CD1 . TRP B 1 75  ? 1.27169   27.44377  -8.16247  1.000 59.37302  ? 74  TRP B CD1 1 
ATOM   4979 C CD2 . TRP B 1 75  ? 2.24889   28.19710  -6.29702  1.000 57.19958  ? 74  TRP B CD2 1 
ATOM   4980 N NE1 . TRP B 1 75  ? 0.58114   28.55707  -7.75268  1.000 55.59192  ? 74  TRP B NE1 1 
ATOM   4981 C CE2 . TRP B 1 75  ? 1.16443   29.03770  -6.60948  1.000 56.74482  ? 74  TRP B CE2 1 
ATOM   4982 C CE3 . TRP B 1 75  ? 3.00734   28.47010  -5.15510  1.000 58.46302  ? 74  TRP B CE3 1 
ATOM   4983 C CZ2 . TRP B 1 75  ? 0.83317   30.13136  -5.83188  1.000 57.34653  ? 74  TRP B CZ2 1 
ATOM   4984 C CZ3 . TRP B 1 75  ? 2.67803   29.54871  -4.39239  1.000 52.61329  ? 74  TRP B CZ3 1 
ATOM   4985 C CH2 . TRP B 1 75  ? 1.60141   30.36956  -4.72982  1.000 60.18948  ? 74  TRP B CH2 1 
ATOM   4986 N N   . CYS B 1 76  ? 6.66548   25.44447  -8.35103  1.000 48.88592  ? 75  CYS B N   1 
ATOM   4987 C CA  . CYS B 1 76  ? 7.78025   24.50694  -8.19004  1.000 46.90824  ? 75  CYS B CA  1 
ATOM   4988 C C   . CYS B 1 76  ? 8.18617   24.46157  -6.71615  1.000 57.50817  ? 75  CYS B C   1 
ATOM   4989 O O   . CYS B 1 76  ? 9.18204   25.04929  -6.28844  1.000 57.47148  ? 75  CYS B O   1 
ATOM   4990 C CB  . CYS B 1 76  ? 8.93841   24.92831  -9.08594  1.000 47.10186  ? 75  CYS B CB  1 
ATOM   4991 S SG  . CYS B 1 76  ? 10.41601  23.89543  -9.02446  1.000 60.80671  ? 75  CYS B SG  1 
ATOM   4992 N N   . ILE B 1 77  ? 7.39463   23.73488  -5.92316  1.000 64.18447  ? 76  ILE B N   1 
ATOM   4993 C CA  . ILE B 1 77  ? 7.57078   23.73853  -4.47185  1.000 57.62709  ? 76  ILE B CA  1 
ATOM   4994 C C   . ILE B 1 77  ? 8.84885   23.01299  -4.08366  1.000 59.68379  ? 76  ILE B C   1 
ATOM   4995 O O   . ILE B 1 77  ? 9.15571   21.92996  -4.60096  1.000 61.02847  ? 76  ILE B O   1 
ATOM   4996 C CB  . ILE B 1 77  ? 6.35613   23.09863  -3.78803  1.000 51.44827  ? 76  ILE B CB  1 
ATOM   4997 C CG1 . ILE B 1 77  ? 5.15649   24.03732  -3.89717  1.000 50.50352  ? 76  ILE B CG1 1 
ATOM   4998 C CG2 . ILE B 1 77  ? 6.68658   22.75371  -2.36132  1.000 50.00672  ? 76  ILE B CG2 1 
ATOM   4999 C CD1 . ILE B 1 77  ? 3.91807   23.51279  -3.24581  1.000 48.23126  ? 76  ILE B CD1 1 
ATOM   5000 N N   . ASP B 1 78  ? 9.60127   23.60483  -3.15817  1.000 66.18386  ? 77  ASP B N   1 
ATOM   5001 C CA  . ASP B 1 78  ? 10.82250  22.96607  -2.68694  1.000 68.21846  ? 77  ASP B CA  1 
ATOM   5002 C C   . ASP B 1 78  ? 10.49227  21.77694  -1.79600  1.000 68.44657  ? 77  ASP B C   1 
ATOM   5003 O O   . ASP B 1 78  ? 9.76413   21.90888  -0.80716  1.000 62.26094  ? 77  ASP B O   1 
ATOM   5004 C CB  . ASP B 1 78  ? 11.68787  23.95745  -1.92364  1.000 71.95275  ? 77  ASP B CB  1 
ATOM   5005 C CG  . ASP B 1 78  ? 13.04293  23.37629  -1.54723  1.000 76.62280  ? 77  ASP B CG  1 
ATOM   5006 O OD1 . ASP B 1 78  ? 13.23485  22.14324  -1.68535  1.000 74.31822  ? 77  ASP B OD1 1 
ATOM   5007 O OD2 . ASP B 1 78  ? 13.91856  24.15885  -1.10441  1.000 80.03084  ? 77  ASP B OD2 1 
ATOM   5008 N N   . ALA B 1 79  ? 11.06029  20.62057  -2.13813  1.000 72.81393  ? 78  ALA B N   1 
ATOM   5009 C CA  . ALA B 1 79  ? 10.82152  19.38492  -1.40219  1.000 69.48295  ? 78  ALA B CA  1 
ATOM   5010 C C   . ALA B 1 79  ? 11.19649  19.52366  0.06918   1.000 68.46430  ? 78  ALA B C   1 
ATOM   5011 O O   . ALA B 1 79  ? 10.32115  19.49707  0.94344   1.000 67.05616  ? 78  ALA B O   1 
ATOM   5012 C CB  . ALA B 1 79  ? 11.60173  18.23438  -2.04060  1.000 64.32315  ? 78  ALA B CB  1 
ATOM   5013 N N   . ALA B 1 80  ? 12.49330  19.68953  0.34986   1.000 66.08730  ? 79  ALA B N   1 
ATOM   5014 C CA  . ALA B 1 80  ? 13.00283  19.70896  1.71778   1.000 60.33549  ? 79  ALA B CA  1 
ATOM   5015 C C   . ALA B 1 80  ? 12.56186  20.93388  2.50900   1.000 63.92306  ? 79  ALA B C   1 
ATOM   5016 O O   . ALA B 1 80  ? 12.93502  21.05060  3.68058   1.000 72.32870  ? 79  ALA B O   1 
ATOM   5017 C CB  . ALA B 1 80  ? 14.52867  19.62148  1.70792   1.000 56.75103  ? 79  ALA B CB  1 
ATOM   5018 N N   . SER B 1 81  ? 11.78514  21.83874  1.91832   1.000 63.77450  ? 80  SER B N   1 
ATOM   5019 C CA  . SER B 1 81  ? 11.24978  22.99662  2.62209   1.000 59.00572  ? 80  SER B CA  1 
ATOM   5020 C C   . SER B 1 81  ? 9.89682   22.72115  3.26850   1.000 62.29733  ? 80  SER B C   1 
ATOM   5021 O O   . SER B 1 81  ? 9.36136   23.59022  3.96986   1.000 55.95905  ? 80  SER B O   1 
ATOM   5022 C CB  . SER B 1 81  ? 11.13444  24.18327  1.65219   1.000 64.83087  ? 80  SER B CB  1 
ATOM   5023 O OG  . SER B 1 81  ? 9.79069   24.50975  1.30882   1.000 61.25220  ? 80  SER B OG  1 
ATOM   5024 N N   . LEU B 1 82  ? 9.32696   21.53962  3.04681   1.000 66.44561  ? 81  LEU B N   1 
ATOM   5025 C CA  . LEU B 1 82  ? 7.99924   21.25879  3.56779   1.000 63.23244  ? 81  LEU B CA  1 
ATOM   5026 C C   . LEU B 1 82  ? 8.05169   21.07956  5.07542   1.000 59.08809  ? 81  LEU B C   1 
ATOM   5027 O O   . LEU B 1 82  ? 8.82771   20.27006  5.59419   1.000 51.99807  ? 81  LEU B O   1 
ATOM   5028 C CB  . LEU B 1 82  ? 7.40153   20.02393  2.90125   1.000 62.31605  ? 81  LEU B CB  1 
ATOM   5029 C CG  . LEU B 1 82  ? 6.37049   20.49015  1.88276   1.000 57.29794  ? 81  LEU B CG  1 
ATOM   5030 C CD1 . LEU B 1 82  ? 5.29638   21.30685  2.58798   1.000 53.59237  ? 81  LEU B CD1 1 
ATOM   5031 C CD2 . LEU B 1 82  ? 7.03004   21.32075  0.82140   1.000 64.75472  ? 81  LEU B CD2 1 
ATOM   5032 N N   . ARG B 1 83  ? 7.23688   21.86341  5.77190   1.000 56.25292  ? 82  ARG B N   1 
ATOM   5033 C CA  . ARG B 1 83  ? 7.14758   21.81233  7.21976   1.000 56.33686  ? 82  ARG B CA  1 
ATOM   5034 C C   . ARG B 1 83  ? 5.68085   21.91563  7.60964   1.000 56.60329  ? 82  ARG B C   1 
ATOM   5035 O O   . ARG B 1 83  ? 4.96084   22.80334  7.13640   1.000 53.92711  ? 82  ARG B O   1 
ATOM   5036 C CB  . ARG B 1 83  ? 7.97368   22.93277  7.86604   1.000 52.00166  ? 82  ARG B CB  1 
ATOM   5037 N N   . ARG B 1 84  ? 5.24424   20.99281  8.45849   1.000 55.57017  ? 83  ARG B N   1 
ATOM   5038 C CA  . ARG B 1 84  ? 3.86111   20.91108  8.91178   1.000 61.84212  ? 83  ARG B CA  1 
ATOM   5039 C C   . ARG B 1 84  ? 3.86020   21.12533  10.42103  1.000 68.25484  ? 83  ARG B C   1 
ATOM   5040 O O   . ARG B 1 84  ? 4.39518   20.29728  11.16646  1.000 66.57336  ? 83  ARG B O   1 
ATOM   5041 C CB  . ARG B 1 84  ? 3.25410   19.55512  8.53623   1.000 61.86164  ? 83  ARG B CB  1 
ATOM   5042 C CG  . ARG B 1 84  ? 1.84380   19.33585  9.02620   1.000 55.71852  ? 83  ARG B CG  1 
ATOM   5043 C CD  . ARG B 1 84  ? 1.42388   17.88922  8.89922   1.000 54.10792  ? 83  ARG B CD  1 
ATOM   5044 N NE  . ARG B 1 84  ? 0.06403   17.72236  9.39788   1.000 60.59159  ? 83  ARG B NE  1 
ATOM   5045 C CZ  . ARG B 1 84  ? -0.43614  16.58860  9.87230   1.000 61.31413  ? 83  ARG B CZ  1 
ATOM   5046 N NH1 . ARG B 1 84  ? 0.28176   15.46731  9.89758   1.000 52.94588  ? 83  ARG B NH1 1 
ATOM   5047 N NH2 . ARG B 1 84  ? -1.68898  16.57835  10.32798  1.000 53.68067  ? 83  ARG B NH2 1 
ATOM   5048 N N   . VAL B 1 85  ? 3.27462   22.23401  10.87296  1.000 69.10546  ? 84  VAL B N   1 
ATOM   5049 C CA  . VAL B 1 85  ? 3.21428   22.57772  12.29297  1.000 68.85264  ? 84  VAL B CA  1 
ATOM   5050 C C   . VAL B 1 85  ? 1.75607   22.58815  12.73085  1.000 68.78882  ? 84  VAL B C   1 
ATOM   5051 O O   . VAL B 1 85  ? 0.96462   23.41065  12.24835  1.000 67.69750  ? 84  VAL B O   1 
ATOM   5052 C CB  . VAL B 1 85  ? 3.87203   23.93387  12.58595  1.000 67.86601  ? 84  VAL B CB  1 
ATOM   5053 C CG1 . VAL B 1 85  ? 3.93191   24.16032  14.09043  1.000 62.51426  ? 84  VAL B CG1 1 
ATOM   5054 C CG2 . VAL B 1 85  ? 5.26251   24.01251  11.93979  1.000 59.65645  ? 84  VAL B CG2 1 
ATOM   5055 N N   . ARG B 1 86  ? 1.40017   21.67984  13.64090  1.000 70.36130  ? 85  ARG B N   1 
ATOM   5056 C CA  . ARG B 1 86  ? 0.04021   21.58470  14.16168  1.000 74.59787  ? 85  ARG B CA  1 
ATOM   5057 C C   . ARG B 1 86  ? 0.06157   21.94454  15.63337  1.000 71.09671  ? 85  ARG B C   1 
ATOM   5058 O O   . ARG B 1 86  ? 0.83395   21.35374  16.40135  1.000 70.45807  ? 85  ARG B O   1 
ATOM   5059 C CB  . ARG B 1 86  ? -0.56583  20.18692  13.97301  1.000 70.51255  ? 85  ARG B CB  1 
ATOM   5060 N N   . LYS B 1 87  ? -0.79525  22.91246  16.00304  1.000 74.51813  ? 86  LYS B N   1 
ATOM   5061 C CA  . LYS B 1 87  ? -0.93070  23.48937  17.34030  1.000 69.18558  ? 86  LYS B CA  1 
ATOM   5062 C C   . LYS B 1 87  ? 0.40202   23.46388  18.08837  1.000 70.30699  ? 86  LYS B C   1 
ATOM   5063 O O   . LYS B 1 87  ? 0.56023   22.75180  19.08781  1.000 69.36791  ? 86  LYS B O   1 
ATOM   5064 C CB  . LYS B 1 87  ? -2.03401  22.76250  18.12055  1.000 52.38052  ? 86  LYS B CB  1 
ATOM   5065 N N   . GLY B 1 88  ? 1.37878   24.21183  17.58249  1.000 63.53636  ? 87  GLY B N   1 
ATOM   5066 C CA  . GLY B 1 88  ? 2.68452   24.25277  18.19932  1.000 62.62504  ? 87  GLY B CA  1 
ATOM   5067 C C   . GLY B 1 88  ? 3.65638   23.23068  17.65496  1.000 64.56106  ? 87  GLY B C   1 
ATOM   5068 O O   . GLY B 1 88  ? 4.73254   23.60794  17.17929  1.000 66.73010  ? 87  GLY B O   1 
ATOM   5069 N N   . GLU B 1 89  ? 3.29582   21.94513  17.71870  1.000 61.64979  ? 88  GLU B N   1 
ATOM   5070 C CA  . GLU B 1 89  ? 4.23275   20.87757  17.38551  1.000 63.40314  ? 88  GLU B CA  1 
ATOM   5071 C C   . GLU B 1 89  ? 4.48083   20.81600  15.88443  1.000 71.80250  ? 88  GLU B C   1 
ATOM   5072 O O   . GLU B 1 89  ? 3.60204   21.11593  15.06857  1.000 69.30417  ? 88  GLU B O   1 
ATOM   5073 C CB  . GLU B 1 89  ? 3.71444   19.52165  17.86640  1.000 60.50824  ? 88  GLU B CB  1 
ATOM   5074 N N   . GLU B 1 90  ? 5.70666   20.44449  15.52834  1.000 65.82516  ? 89  GLU B N   1 
ATOM   5075 C CA  . GLU B 1 90  ? 6.05362   20.14549  14.15056  1.000 61.48975  ? 89  GLU B CA  1 
ATOM   5076 C C   . GLU B 1 90  ? 5.80639   18.66264  13.90357  1.000 68.33015  ? 89  GLU B C   1 
ATOM   5077 O O   . GLU B 1 90  ? 6.08698   17.83111  14.77004  1.000 68.59178  ? 89  GLU B O   1 
ATOM   5078 C CB  . GLU B 1 90  ? 7.51205   20.50968  13.86137  1.000 58.48285  ? 89  GLU B CB  1 
ATOM   5079 N N   . LEU B 1 91  ? 5.28004   18.33814  12.71055  1.000 73.64178  ? 90  LEU B N   1 
ATOM   5080 C CA  . LEU B 1 91  ? 4.69318   17.03542  12.40095  1.000 62.41861  ? 90  LEU B CA  1 
ATOM   5081 C C   . LEU B 1 91  ? 5.26339   16.47173  11.10817  1.000 59.50755  ? 90  LEU B C   1 
ATOM   5082 O O   . LEU B 1 91  ? 5.69243   17.22034  10.22770  1.000 70.14343  ? 90  LEU B O   1 
ATOM   5083 C CB  . LEU B 1 91  ? 3.15931   17.15102  12.26895  1.000 61.54991  ? 90  LEU B CB  1 
ATOM   5084 C CG  . LEU B 1 91  ? 2.30703   17.13753  13.54825  1.000 65.88611  ? 90  LEU B CG  1 
ATOM   5085 C CD1 . LEU B 1 91  ? 2.32259   18.48472  14.21174  1.000 69.56164  ? 90  LEU B CD1 1 
ATOM   5086 C CD2 . LEU B 1 91  ? 0.86928   16.76822  13.23758  1.000 60.35399  ? 90  LEU B CD2 1 
ATOM   5087 N N   . ARG B 1 92  ? 5.27757   15.13811  11.01611  1.000 63.47096  ? 91  ARG B N   1 
ATOM   5088 C CA  . ARG B 1 92  ? 5.35211   14.40142  9.75293   1.000 56.21372  ? 91  ARG B CA  1 
ATOM   5089 C C   . ARG B 1 92  ? 4.63030   15.13212  8.63449   1.000 61.50516  ? 91  ARG B C   1 
ATOM   5090 O O   . ARG B 1 92  ? 3.46472   15.51735  8.80282   1.000 62.57099  ? 91  ARG B O   1 
ATOM   5091 C CB  . ARG B 1 92  ? 4.67529   13.04364  9.91414   1.000 65.14355  ? 91  ARG B CB  1 
ATOM   5092 C CG  . ARG B 1 92  ? 5.26755   11.82031  9.24781   1.000 66.55024  ? 91  ARG B CG  1 
ATOM   5093 C CD  . ARG B 1 92  ? 4.48394   10.55850  9.75000   1.000 77.91716  ? 91  ARG B CD  1 
ATOM   5094 N NE  . ARG B 1 92  ? 3.02231   10.70308  9.69586   1.000 80.61858  ? 91  ARG B NE  1 
ATOM   5095 C CZ  . ARG B 1 92  ? 2.22958   11.02027  10.72083  1.000 83.06717  ? 91  ARG B CZ  1 
ATOM   5096 N NH1 . ARG B 1 92  ? 2.71432   11.23210  11.94151  1.000 78.21663  ? 91  ARG B NH1 1 
ATOM   5097 N NH2 . ARG B 1 92  ? 0.91698   11.14872  10.51212  1.000 71.40817  ? 91  ARG B NH2 1 
ATOM   5098 N N   . ILE B 1 93  ? 5.28460   15.31966  7.49074   1.000 58.93629  ? 92  ILE B N   1 
ATOM   5099 C CA  . ILE B 1 93  ? 4.52477   15.63956  6.29122   1.000 55.86812  ? 92  ILE B CA  1 
ATOM   5100 C C   . ILE B 1 93  ? 3.79350   14.37491  5.85912   1.000 57.83317  ? 92  ILE B C   1 
ATOM   5101 O O   . ILE B 1 93  ? 4.40922   13.31989  5.66236   1.000 54.04091  ? 92  ILE B O   1 
ATOM   5102 C CB  . ILE B 1 93  ? 5.42992   16.18538  5.18336   1.000 56.69080  ? 92  ILE B CB  1 
ATOM   5103 C CG1 . ILE B 1 93  ? 5.56437   17.69954  5.33935   1.000 56.72290  ? 92  ILE B CG1 1 
ATOM   5104 C CG2 . ILE B 1 93  ? 4.86938   15.83354  3.79127   1.000 53.92172  ? 92  ILE B CG2 1 
ATOM   5105 C CD1 . ILE B 1 93  ? 4.30360   18.47033  5.00631   1.000 48.48904  ? 92  ILE B CD1 1 
ATOM   5106 N N   . ASP B 1 94  ? 2.47015   14.46378  5.74481   1.000 53.72247  ? 93  ASP B N   1 
ATOM   5107 C CA  . ASP B 1 94  ? 1.66064   13.29749  5.42905   1.000 55.53846  ? 93  ASP B CA  1 
ATOM   5108 C C   . ASP B 1 94  ? 0.53732   13.68082  4.47375   1.000 61.09463  ? 93  ASP B C   1 
ATOM   5109 O O   . ASP B 1 94  ? -0.26426  14.57572  4.77624   1.000 59.32563  ? 93  ASP B O   1 
ATOM   5110 C CB  . ASP B 1 94  ? 1.09663   12.67995  6.70523   1.000 61.07016  ? 93  ASP B CB  1 
ATOM   5111 C CG  . ASP B 1 94  ? 0.13933   11.55341  6.42627   1.000 63.66758  ? 93  ASP B CG  1 
ATOM   5112 O OD1 . ASP B 1 94  ? 0.60666   10.43514  6.11628   1.000 66.85755  ? 93  ASP B OD1 1 
ATOM   5113 O OD2 . ASP B 1 94  ? -1.08434  11.79237  6.51087   1.000 62.39903  ? 93  ASP B OD2 1 
ATOM   5114 N N   . ALA B 1 95  ? 0.46734   12.96535  3.33960   1.000 54.76483  ? 94  ALA B N   1 
ATOM   5115 C CA  . ALA B 1 95  ? -0.38513  13.38166  2.23118   1.000 52.02241  ? 94  ALA B CA  1 
ATOM   5116 C C   . ALA B 1 95  ? -1.86405  13.13088  2.51331   1.000 51.83426  ? 94  ALA B C   1 
ATOM   5117 O O   . ALA B 1 95  ? -2.71709  13.96186  2.17268   1.000 48.88668  ? 94  ALA B O   1 
ATOM   5118 C CB  . ALA B 1 95  ? 0.04786   12.66662  0.95876   1.000 50.75780  ? 94  ALA B CB  1 
ATOM   5119 N N   . ILE B 1 96  ? -2.19758  11.98584  3.10981   1.000 55.18972  ? 95  ILE B N   1 
ATOM   5120 C CA  . ILE B 1 96  ? -3.58686  11.76264  3.51464   1.000 56.35672  ? 95  ILE B CA  1 
ATOM   5121 C C   . ILE B 1 96  ? -4.02990  12.81930  4.52403   1.000 54.67676  ? 95  ILE B C   1 
ATOM   5122 O O   . ILE B 1 96  ? -5.19385  13.24595  4.52057   1.000 51.53181  ? 95  ILE B O   1 
ATOM   5123 C CB  . ILE B 1 96  ? -3.79461  10.33644  4.07817   1.000 49.62553  ? 95  ILE B CB  1 
ATOM   5124 C CG1 . ILE B 1 96  ? -3.18244  9.25180   3.16568   1.000 50.50915  ? 95  ILE B CG1 1 
ATOM   5125 C CG2 . ILE B 1 96  ? -5.28179  10.09062  4.28520   1.000 44.34951  ? 95  ILE B CG2 1 
ATOM   5126 C CD1 . ILE B 1 96  ? -1.66974  8.94732   3.40266   1.000 54.19439  ? 95  ILE B CD1 1 
ATOM   5127 N N   . ASP B 1 97  ? -3.11421  13.26728  5.39304   1.000 55.01364  ? 96  ASP B N   1 
ATOM   5128 C CA  . ASP B 1 97  ? -3.46869  14.26176  6.40374   1.000 58.97064  ? 96  ASP B CA  1 
ATOM   5129 C C   . ASP B 1 97  ? -3.76054  15.62005  5.77061   1.000 58.55068  ? 96  ASP B C   1 
ATOM   5130 O O   . ASP B 1 97  ? -4.80083  16.23219  6.04326   1.000 52.24978  ? 96  ASP B O   1 
ATOM   5131 C CB  . ASP B 1 97  ? -2.35700  14.37189  7.45177   1.000 63.85282  ? 96  ASP B CB  1 
ATOM   5132 C CG  . ASP B 1 97  ? -2.69428  13.63264  8.75904   1.000 67.38991  ? 96  ASP B CG  1 
ATOM   5133 O OD1 . ASP B 1 97  ? -3.72471  13.98334  9.38646   1.000 64.05000  ? 96  ASP B OD1 1 
ATOM   5134 O OD2 . ASP B 1 97  ? -1.92039  12.72981  9.17126   1.000 72.43387  ? 96  ASP B OD2 1 
ATOM   5135 N N   . LEU B 1 98  ? -2.85040  16.10153  4.92078   1.000 57.52800  ? 97  LEU B N   1 
ATOM   5136 C CA  . LEU B 1 98  ? -3.08187  17.30447  4.12607   1.000 51.73763  ? 97  LEU B CA  1 
ATOM   5137 C C   . LEU B 1 98  ? -4.48185  17.36671  3.50126   1.000 56.45681  ? 97  LEU B C   1 
ATOM   5138 O O   . LEU B 1 98  ? -5.16941  18.39047  3.60012   1.000 53.89583  ? 97  LEU B O   1 
ATOM   5139 C CB  . LEU B 1 98  ? -2.01315  17.36818  3.04036   1.000 48.75401  ? 97  LEU B CB  1 
ATOM   5140 C CG  . LEU B 1 98  ? -1.47480  18.71475  2.58015   1.000 49.08372  ? 97  LEU B CG  1 
ATOM   5141 C CD1 . LEU B 1 98  ? -0.43381  18.49355  1.47749   1.000 44.41463  ? 97  LEU B CD1 1 
ATOM   5142 C CD2 . LEU B 1 98  ? -2.59612  19.63707  2.12142   1.000 49.85501  ? 97  LEU B CD2 1 
ATOM   5143 N N   . ILE B 1 99  ? -4.91215  16.28355  2.83525   1.000 59.19191  ? 98  ILE B N   1 
ATOM   5144 C CA  . ILE B 1 99  ? -6.21499  16.27866  2.16315   1.000 55.07209  ? 98  ILE B CA  1 
ATOM   5145 C C   . ILE B 1 99  ? -7.34150  16.49637  3.16576   1.000 58.04698  ? 98  ILE B C   1 
ATOM   5146 O O   . ILE B 1 99  ? -8.27605  17.26434  2.91375   1.000 57.71399  ? 98  ILE B O   1 
ATOM   5147 C CB  . ILE B 1 99  ? -6.41929  14.96681  1.38513   1.000 56.44759  ? 98  ILE B CB  1 
ATOM   5148 C CG1 . ILE B 1 99  ? -5.28404  14.73908  0.37449   1.000 59.07648  ? 98  ILE B CG1 1 
ATOM   5149 C CG2 . ILE B 1 99  ? -7.78428  14.97598  0.70162   1.000 56.10066  ? 98  ILE B CG2 1 
ATOM   5150 C CD1 . ILE B 1 99  ? -5.60942  15.15850  -1.04057  1.000 51.89254  ? 98  ILE B CD1 1 
ATOM   5151 N N   . VAL B 1 100 ? -7.27907  15.81322  4.31350   1.000 62.69207  ? 99  VAL B N   1 
ATOM   5152 C CA  . VAL B 1 100 ? -8.31299  15.96755  5.33831   1.000 62.51623  ? 99  VAL B CA  1 
ATOM   5153 C C   . VAL B 1 100 ? -8.30009  17.38410  5.90058   1.000 63.71841  ? 99  VAL B C   1 
ATOM   5154 O O   . VAL B 1 100 ? -9.35538  17.99029  6.13471   1.000 61.11772  ? 99  VAL B O   1 
ATOM   5155 C CB  . VAL B 1 100 ? -8.12240  14.92286  6.45564   1.000 59.09671  ? 99  VAL B CB  1 
ATOM   5156 C CG1 . VAL B 1 100 ? -8.97472  15.27968  7.65837   1.000 56.36267  ? 99  VAL B CG1 1 
ATOM   5157 C CG2 . VAL B 1 100 ? -8.45040  13.51973  5.96252   1.000 54.85583  ? 99  VAL B CG2 1 
ATOM   5158 N N   . ASP B 1 101 ? -7.10031  17.92929  6.12465   1.000 65.26202  ? 100 ASP B N   1 
ATOM   5159 C CA  . ASP B 1 101 ? -6.95371  19.27386  6.67269   1.000 62.55547  ? 100 ASP B CA  1 
ATOM   5160 C C   . ASP B 1 101 ? -7.69108  20.31615  5.84177   1.000 65.91383  ? 100 ASP B C   1 
ATOM   5161 O O   . ASP B 1 101 ? -8.15585  21.32480  6.38371   1.000 75.83670  ? 100 ASP B O   1 
ATOM   5162 C CB  . ASP B 1 101 ? -5.47090  19.63853  6.75197   1.000 58.43116  ? 100 ASP B CB  1 
ATOM   5163 C CG  . ASP B 1 101 ? -4.91971  19.52364  8.13881   1.000 59.67806  ? 100 ASP B CG  1 
ATOM   5164 O OD1 . ASP B 1 101 ? -5.68715  19.77940  9.09440   1.000 67.77951  ? 100 ASP B OD1 1 
ATOM   5165 O OD2 . ASP B 1 101 ? -3.71907  19.18761  8.26984   1.000 59.38140  ? 100 ASP B OD2 1 
ATOM   5166 N N   . MET B 1 102 ? -7.79867  20.10575  4.53011   1.000 63.47757  ? 101 MET B N   1 
ATOM   5167 C CA  . MET B 1 102 ? -8.30810  21.13198  3.63020   1.000 63.80090  ? 101 MET B CA  1 
ATOM   5168 C C   . MET B 1 102 ? -9.52582  20.66172  2.84814   1.000 64.37273  ? 101 MET B C   1 
ATOM   5169 O O   . MET B 1 102 ? -9.89748  21.28825  1.85388   1.000 67.27528  ? 101 MET B O   1 
ATOM   5170 C CB  . MET B 1 102 ? -7.18215  21.59503  2.70503   1.000 60.18081  ? 101 MET B CB  1 
ATOM   5171 C CG  . MET B 1 102 ? -5.90956  21.83644  3.50986   1.000 70.12723  ? 101 MET B CG  1 
ATOM   5172 S SD  . MET B 1 102 ? -4.92869  23.26550  3.02972   1.000 79.32871  ? 101 MET B SD  1 
ATOM   5173 C CE  . MET B 1 102 ? -6.18726  24.54242  3.01477   1.000 66.22704  ? 101 MET B CE  1 
ATOM   5174 N N   . SER B 1 103 ? -10.17241 19.58622  3.30809   1.000 64.03064  ? 102 SER B N   1 
ATOM   5175 C CA  . SER B 1 103 ? -11.31688 19.02508  2.59885   1.000 63.78115  ? 102 SER B CA  1 
ATOM   5176 C C   . SER B 1 103 ? -12.39765 20.06847  2.34051   1.000 71.14304  ? 102 SER B C   1 
ATOM   5177 O O   . SER B 1 103 ? -13.11962 19.97520  1.33996   1.000 68.78165  ? 102 SER B O   1 
ATOM   5178 C CB  . SER B 1 103 ? -11.89031 17.84312  3.38581   1.000 62.78166  ? 102 SER B CB  1 
ATOM   5179 O OG  . SER B 1 103 ? -11.75533 18.03460  4.78662   1.000 64.03120  ? 102 SER B OG  1 
ATOM   5180 N N   . GLY B 1 104 ? -12.52376 21.06475  3.22085   1.000 78.00052  ? 103 GLY B N   1 
ATOM   5181 C CA  . GLY B 1 104 ? -13.44852 22.16563  3.00865   1.000 73.34819  ? 103 GLY B CA  1 
ATOM   5182 C C   . GLY B 1 104 ? -13.01178 23.05860  1.86532   1.000 75.01244  ? 103 GLY B C   1 
ATOM   5183 O O   . GLY B 1 104 ? -13.66303 23.10485  0.81521   1.000 74.65221  ? 103 GLY B O   1 
ATOM   5184 N N   . SER B 1 105 ? -11.87956 23.74560  2.05245   1.000 75.23689  ? 104 SER B N   1 
ATOM   5185 C CA  . SER B 1 105 ? -11.30997 24.60340  1.01723   1.000 72.85026  ? 104 SER B CA  1 
ATOM   5186 C C   . SER B 1 105 ? -11.19709 23.90906  -0.33434  1.000 70.64215  ? 104 SER B C   1 
ATOM   5187 O O   . SER B 1 105 ? -11.05444 24.58937  -1.35756  1.000 80.03903  ? 104 SER B O   1 
ATOM   5188 C CB  . SER B 1 105 ? -9.93050  25.09207  1.46228   1.000 71.06387  ? 104 SER B CB  1 
ATOM   5189 O OG  . SER B 1 105 ? -9.85976  25.15958  2.87360   1.000 64.02229  ? 104 SER B OG  1 
ATOM   5190 N N   . LEU B 1 106 ? -11.24353 22.57618  -0.36136  1.000 67.73704  ? 105 LEU B N   1 
ATOM   5191 C CA  . LEU B 1 106 ? -11.26428 21.79956  -1.59384  1.000 70.21134  ? 105 LEU B CA  1 
ATOM   5192 C C   . LEU B 1 106 ? -12.66869 21.59092  -2.15123  1.000 69.12384  ? 105 LEU B C   1 
ATOM   5193 O O   . LEU B 1 106 ? -12.80325 21.05040  -3.25248  1.000 64.96850  ? 105 LEU B O   1 
ATOM   5194 C CB  . LEU B 1 106 ? -10.61729 20.43484  -1.35485  1.000 69.89601  ? 105 LEU B CB  1 
ATOM   5195 C CG  . LEU B 1 106 ? -9.20749  20.18838  -1.86940  1.000 68.07478  ? 105 LEU B CG  1 
ATOM   5196 C CD1 . LEU B 1 106 ? -8.30199  21.31074  -1.41953  1.000 65.19106  ? 105 LEU B CD1 1 
ATOM   5197 C CD2 . LEU B 1 106 ? -8.72903  18.85849  -1.31545  1.000 61.67347  ? 105 LEU B CD2 1 
ATOM   5198 N N   . GLY B 1 107 ? -13.70883 21.98349  -1.42181  1.000 65.42367  ? 106 GLY B N   1 
ATOM   5199 C CA  . GLY B 1 107 ? -15.05984 21.80204  -1.92102  1.000 61.81415  ? 106 GLY B CA  1 
ATOM   5200 C C   . GLY B 1 107 ? -15.45787 20.35019  -2.03314  1.000 66.81341  ? 106 GLY B C   1 
ATOM   5201 O O   . GLY B 1 107 ? -16.12479 19.96054  -2.99917  1.000 72.02440  ? 106 GLY B O   1 
ATOM   5202 N N   . ILE B 1 108 ? -15.05459 19.53663  -1.06324  1.000 72.65829  ? 107 ILE B N   1 
ATOM   5203 C CA  . ILE B 1 108 ? -15.37291 18.11016  -1.02275  1.000 71.11718  ? 107 ILE B CA  1 
ATOM   5204 C C   . ILE B 1 108 ? -16.53840 17.89744  -0.06817  1.000 64.37218  ? 107 ILE B C   1 
ATOM   5205 O O   . ILE B 1 108 ? -16.32296 17.91562  1.15067   1.000 68.48397  ? 107 ILE B O   1 
ATOM   5206 C CB  . ILE B 1 108 ? -14.16046 17.27478  -0.57404  1.000 67.46245  ? 107 ILE B CB  1 
ATOM   5207 C CG1 . ILE B 1 108 ? -12.93626 17.57486  -1.44901  1.000 66.69931  ? 107 ILE B CG1 1 
ATOM   5208 C CG2 . ILE B 1 108 ? -14.50837 15.80010  -0.58352  1.000 56.84105  ? 107 ILE B CG2 1 
ATOM   5209 C CD1 . ILE B 1 108 ? -11.82327 16.56372  -1.32999  1.000 57.81340  ? 107 ILE B CD1 1 
ATOM   5210 N N   . PRO B 1 109 ? -17.77944 17.68964  -0.56704  1.000 66.44302  ? 108 PRO B N   1 
ATOM   5211 C CA  . PRO B 1 109 ? -18.91403 17.42458  0.33232   1.000 60.61769  ? 108 PRO B CA  1 
ATOM   5212 C C   . PRO B 1 109 ? -18.54607 16.44066  1.41938   1.000 65.69036  ? 108 PRO B C   1 
ATOM   5213 O O   . PRO B 1 109 ? -17.98801 15.38577  1.10504   1.000 72.92243  ? 108 PRO B O   1 
ATOM   5214 C CB  . PRO B 1 109 ? -19.97465 16.83044  -0.60237  1.000 57.10070  ? 108 PRO B CB  1 
ATOM   5215 C CG  . PRO B 1 109 ? -19.67831 17.43150  -1.92668  1.000 55.38738  ? 108 PRO B CG  1 
ATOM   5216 C CD  . PRO B 1 109 ? -18.17593 17.64369  -1.98720  1.000 66.22251  ? 108 PRO B CD  1 
ATOM   5217 N N   . VAL B 1 110 ? -18.80498 16.77618  2.68822   1.000 64.92279  ? 109 VAL B N   1 
ATOM   5218 C CA  . VAL B 1 110 ? -18.54958 15.81452  3.75998   1.000 67.41887  ? 109 VAL B CA  1 
ATOM   5219 C C   . VAL B 1 110 ? -19.34601 14.53587  3.51254   1.000 65.68486  ? 109 VAL B C   1 
ATOM   5220 O O   . VAL B 1 110 ? -18.91177 13.44047  3.89549   1.000 64.37016  ? 109 VAL B O   1 
ATOM   5221 C CB  . VAL B 1 110 ? -18.83960 16.44233  5.14955   1.000 62.47900  ? 109 VAL B CB  1 
ATOM   5222 C CG1 . VAL B 1 110 ? -20.30749 16.37356  5.50681   1.000 54.08007  ? 109 VAL B CG1 1 
ATOM   5223 C CG2 . VAL B 1 110 ? -17.98977 15.77549  6.23841   1.000 56.16090  ? 109 VAL B CG2 1 
ATOM   5224 N N   . ASP B 1 111 ? -20.49251 14.64724  2.82528   1.000 65.59567  ? 110 ASP B N   1 
ATOM   5225 C CA  . ASP B 1 111 ? -21.18328 13.46897  2.30610   1.000 71.58637  ? 110 ASP B CA  1 
ATOM   5226 C C   . ASP B 1 111 ? -20.21440 12.50796  1.61895   1.000 67.76429  ? 110 ASP B C   1 
ATOM   5227 O O   . ASP B 1 111 ? -20.30154 11.29072  1.80508   1.000 67.55419  ? 110 ASP B O   1 
ATOM   5228 C CB  . ASP B 1 111 ? -22.29371 13.89627  1.33559   1.000 66.25392  ? 110 ASP B CB  1 
ATOM   5229 N N   . ALA B 1 112 ? -19.25557 13.03778  0.85585   1.000 67.17027  ? 111 ALA B N   1 
ATOM   5230 C CA  . ALA B 1 112 ? -18.39498 12.22028  0.00940   1.000 65.31973  ? 111 ALA B CA  1 
ATOM   5231 C C   . ALA B 1 112 ? -16.89993 12.41006  0.28553   1.000 62.18210  ? 111 ALA B C   1 
ATOM   5232 O O   . ALA B 1 112 ? -16.09213 12.33247  -0.63741  1.000 61.01668  ? 111 ALA B O   1 
ATOM   5233 C CB  . ALA B 1 112 ? -18.69550 12.49982  -1.46328  1.000 64.18627  ? 111 ALA B CB  1 
ATOM   5234 N N   . LEU B 1 113 ? -16.49358 12.63424  1.53913   1.000 61.60092  ? 112 LEU B N   1 
ATOM   5235 C CA  . LEU B 1 113 ? -15.05334 12.69132  1.79398   1.000 54.48804  ? 112 LEU B CA  1 
ATOM   5236 C C   . LEU B 1 113 ? -14.48206 11.29110  2.01472   1.000 57.76232  ? 112 LEU B C   1 
ATOM   5237 O O   . LEU B 1 113 ? -13.40222 10.98515  1.48902   1.000 54.17000  ? 112 LEU B O   1 
ATOM   5238 C CB  . LEU B 1 113 ? -14.71772 13.59624  2.98433   1.000 49.23949  ? 112 LEU B CB  1 
ATOM   5239 C CG  . LEU B 1 113 ? -13.23164 13.57274  3.35610   1.000 46.95167  ? 112 LEU B CG  1 
ATOM   5240 C CD1 . LEU B 1 113 ? -12.37757 13.93101  2.16661   1.000 53.26555  ? 112 LEU B CD1 1 
ATOM   5241 C CD2 . LEU B 1 113 ? -12.90799 14.49365  4.50772   1.000 53.67497  ? 112 LEU B CD2 1 
ATOM   5242 N N   . PRO B 1 114 ? -15.14765 10.42058  2.79220   1.000 62.01861  ? 113 PRO B N   1 
ATOM   5243 C CA  . PRO B 1 114 ? -14.67093 9.02819   2.89267   1.000 58.25644  ? 113 PRO B CA  1 
ATOM   5244 C C   . PRO B 1 114 ? -14.40469 8.34125   1.55966   1.000 56.77088  ? 113 PRO B C   1 
ATOM   5245 O O   . PRO B 1 114 ? -13.33360 7.74161   1.37580   1.000 55.62903  ? 113 PRO B O   1 
ATOM   5246 C CB  . PRO B 1 114 ? -15.80813 8.35077   3.66358   1.000 57.29671  ? 113 PRO B CB  1 
ATOM   5247 C CG  . PRO B 1 114 ? -16.28465 9.41310   4.57138   1.000 59.04369  ? 113 PRO B CG  1 
ATOM   5248 C CD  . PRO B 1 114 ? -16.21328 10.68445  3.78290   1.000 63.10833  ? 113 PRO B CD  1 
ATOM   5249 N N   . GLU B 1 115 ? -15.35677 8.39174   0.62567   1.000 57.35962  ? 114 GLU B N   1 
ATOM   5250 C CA  . GLU B 1 115 ? -15.15758 7.70479   -0.64651  1.000 56.24036  ? 114 GLU B CA  1 
ATOM   5251 C C   . GLU B 1 115 ? -13.94437 8.26419   -1.38963  1.000 50.90751  ? 114 GLU B C   1 
ATOM   5252 O O   . GLU B 1 115 ? -13.15904 7.51038   -1.97135  1.000 50.86179  ? 114 GLU B O   1 
ATOM   5253 C CB  . GLU B 1 115 ? -16.42602 7.80352   -1.48940  1.000 55.67696  ? 114 GLU B CB  1 
ATOM   5254 C CG  . GLU B 1 115 ? -16.36992 7.03109   -2.80075  1.000 74.22318  ? 114 GLU B CG  1 
ATOM   5255 C CD  . GLU B 1 115 ? -17.62119 6.19096   -3.03430  1.000 91.15846  ? 114 GLU B CD  1 
ATOM   5256 O OE1 . GLU B 1 115 ? -18.62508 6.39334   -2.30356  1.000 91.11045  ? 114 GLU B OE1 1 
ATOM   5257 O OE2 . GLU B 1 115 ? -17.59766 5.33122   -3.94704  1.000 88.19780  ? 114 GLU B OE2 1 
ATOM   5258 N N   . TYR B 1 116 ? -13.74665 9.57995   -1.34354  1.000 51.76664  ? 115 TYR B N   1 
ATOM   5259 C CA  . TYR B 1 116 ? -12.57683 10.16287  -1.98874  1.000 50.22786  ? 115 TYR B CA  1 
ATOM   5260 C C   . TYR B 1 116 ? -11.28922 9.70014   -1.32036  1.000 51.83759  ? 115 TYR B C   1 
ATOM   5261 O O   . TYR B 1 116 ? -10.29258 9.40726   -1.99734  1.000 45.65908  ? 115 TYR B O   1 
ATOM   5262 C CB  . TYR B 1 116 ? -12.65647 11.68937  -1.95636  1.000 47.87062  ? 115 TYR B CB  1 
ATOM   5263 C CG  . TYR B 1 116 ? -11.41747 12.32508  -2.53581  1.000 49.83850  ? 115 TYR B CG  1 
ATOM   5264 C CD1 . TYR B 1 116 ? -11.30899 12.53980  -3.90257  1.000 53.12712  ? 115 TYR B CD1 1 
ATOM   5265 C CD2 . TYR B 1 116 ? -10.34351 12.68804  -1.72466  1.000 51.18855  ? 115 TYR B CD2 1 
ATOM   5266 C CE1 . TYR B 1 116 ? -10.18143 13.10454  -4.44427  1.000 51.86962  ? 115 TYR B CE1 1 
ATOM   5267 C CE2 . TYR B 1 116 ? -9.20466  13.25081  -2.26223  1.000 52.92130  ? 115 TYR B CE2 1 
ATOM   5268 C CZ  . TYR B 1 116 ? -9.13397  13.44792  -3.62482  1.000 50.18607  ? 115 TYR B CZ  1 
ATOM   5269 O OH  . TYR B 1 116 ? -8.02032  13.99312  -4.18641  1.000 46.91882  ? 115 TYR B OH  1 
ATOM   5270 N N   . LEU B 1 117 ? -11.28098 9.67429   0.01579   1.000 52.40520  ? 116 LEU B N   1 
ATOM   5271 C CA  . LEU B 1 117 ? -10.06688 9.34758   0.74726   1.000 43.84418  ? 116 LEU B CA  1 
ATOM   5272 C C   . LEU B 1 117 ? -9.65625  7.91161   0.49956   1.000 44.00156  ? 116 LEU B C   1 
ATOM   5273 O O   . LEU B 1 117 ? -8.45528  7.61171   0.48614   1.000 42.13331  ? 116 LEU B O   1 
ATOM   5274 C CB  . LEU B 1 117 ? -10.27705 9.59723   2.23741   1.000 53.81483  ? 116 LEU B CB  1 
ATOM   5275 C CG  . LEU B 1 117 ? -9.65559  10.83293  2.87413   1.000 50.85737  ? 116 LEU B CG  1 
ATOM   5276 C CD1 . LEU B 1 117 ? -9.48327  10.55861  4.34786   1.000 48.84148  ? 116 LEU B CD1 1 
ATOM   5277 C CD2 . LEU B 1 117 ? -8.32533  11.10995  2.23793   1.000 48.19361  ? 116 LEU B CD2 1 
ATOM   5278 N N   . GLU B 1 118 ? -10.63881 7.01900   0.29803   1.000 46.41989  ? 117 GLU B N   1 
ATOM   5279 C CA  . GLU B 1 118 ? -10.33646 5.65272   -0.12187  1.000 45.43986  ? 117 GLU B CA  1 
ATOM   5280 C C   . GLU B 1 118 ? -9.61770  5.64278   -1.46035  1.000 42.87301  ? 117 GLU B C   1 
ATOM   5281 O O   . GLU B 1 118 ? -8.54365  5.04030   -1.60073  1.000 39.62474  ? 117 GLU B O   1 
ATOM   5282 C CB  . GLU B 1 118 ? -11.60547 4.80548   -0.21966  1.000 43.40436  ? 117 GLU B CB  1 
ATOM   5283 C CG  . GLU B 1 118 ? -11.29831 3.46226   -0.88946  1.000 42.50713  ? 117 GLU B CG  1 
ATOM   5284 C CD  . GLU B 1 118 ? -12.40634 2.42832   -0.78961  1.000 44.34684  ? 117 GLU B CD  1 
ATOM   5285 O OE1 . GLU B 1 118 ? -13.48449 2.74122   -0.23073  1.000 43.15876  ? 117 GLU B OE1 1 
ATOM   5286 O OE2 . GLU B 1 118 ? -12.17270 1.28453   -1.25962  1.000 41.72222  ? 117 GLU B OE2 1 
ATOM   5287 N N   . GLU B 1 119 ? -10.21067 6.30083   -2.46167  1.000 43.62486  ? 118 GLU B N   1 
ATOM   5288 C CA  . GLU B 1 119 ? -9.56721  6.41064   -3.76536  1.000 45.34793  ? 118 GLU B CA  1 
ATOM   5289 C C   . GLU B 1 119 ? -8.16179  6.98064   -3.63593  1.000 44.53121  ? 118 GLU B C   1 
ATOM   5290 O O   . GLU B 1 119 ? -7.23192  6.52350   -4.31352  1.000 41.97151  ? 118 GLU B O   1 
ATOM   5291 C CB  . GLU B 1 119 ? -10.41349 7.27513   -4.69736  1.000 40.68783  ? 118 GLU B CB  1 
ATOM   5292 C CG  . GLU B 1 119 ? -10.17626 6.99323   -6.15940  1.000 47.07067  ? 118 GLU B CG  1 
ATOM   5293 C CD  . GLU B 1 119 ? -11.46401 7.02481   -6.95950  1.000 60.83791  ? 118 GLU B CD  1 
ATOM   5294 O OE1 . GLU B 1 119 ? -12.51640 7.27339   -6.32086  1.000 54.48847  ? 118 GLU B OE1 1 
ATOM   5295 O OE2 . GLU B 1 119 ? -11.41968 6.82694   -8.20954  1.000 57.08119  ? 118 GLU B OE2 1 
ATOM   5296 N N   . PHE B 1 120 ? -7.98402  7.96573   -2.74819  1.000 41.57120  ? 119 PHE B N   1 
ATOM   5297 C CA  . PHE B 1 120 ? -6.67321  8.57864   -2.58779  1.000 40.83428  ? 119 PHE B CA  1 
ATOM   5298 C C   . PHE B 1 120 ? -5.71335  7.64332   -1.86720  1.000 46.11357  ? 119 PHE B C   1 
ATOM   5299 O O   . PHE B 1 120 ? -4.54372  7.52665   -2.25728  1.000 44.89994  ? 119 PHE B O   1 
ATOM   5300 C CB  . PHE B 1 120 ? -6.79879  9.89946   -1.84224  1.000 41.92595  ? 119 PHE B CB  1 
ATOM   5301 C CG  . PHE B 1 120 ? -5.48921  10.58962  -1.61984  1.000 45.23278  ? 119 PHE B CG  1 
ATOM   5302 C CD1 . PHE B 1 120 ? -5.00118  11.48743  -2.54634  1.000 55.93692  ? 119 PHE B CD1 1 
ATOM   5303 C CD2 . PHE B 1 120 ? -4.74020  10.34034  -0.48815  1.000 49.05088  ? 119 PHE B CD2 1 
ATOM   5304 C CE1 . PHE B 1 120 ? -3.78425  12.12944  -2.35083  1.000 53.39865  ? 119 PHE B CE1 1 
ATOM   5305 C CE2 . PHE B 1 120 ? -3.52495  10.97118  -0.29223  1.000 53.36913  ? 119 PHE B CE2 1 
ATOM   5306 C CZ  . PHE B 1 120 ? -3.05060  11.86958  -1.22549  1.000 52.13591  ? 119 PHE B CZ  1 
ATOM   5307 N N   . THR B 1 121 ? -6.18226  6.96824   -0.81203  1.000 46.38353  ? 120 THR B N   1 
ATOM   5308 C CA  . THR B 1 121 ? -5.30091  6.05916   -0.08604  1.000 42.23318  ? 120 THR B CA  1 
ATOM   5309 C C   . THR B 1 121 ? -4.75868  4.97370   -1.00599  1.000 41.00193  ? 120 THR B C   1 
ATOM   5310 O O   . THR B 1 121 ? -3.55884  4.66533   -0.97223  1.000 36.83242  ? 120 THR B O   1 
ATOM   5311 C CB  . THR B 1 121 ? -6.03718  5.45407   1.10516   1.000 37.47662  ? 120 THR B CB  1 
ATOM   5312 O OG1 . THR B 1 121 ? -6.16894  6.45539   2.11584   1.000 44.70499  ? 120 THR B OG1 1 
ATOM   5313 C CG2 . THR B 1 121 ? -5.25859  4.28979   1.68229   1.000 33.77700  ? 120 THR B CG2 1 
ATOM   5314 N N   . ASN B 1 122 ? -5.62664  4.41046   -1.86019  1.000 45.46625  ? 121 ASN B N   1 
ATOM   5315 C CA  . ASN B 1 122 ? -5.19432  3.41965   -2.84635  1.000 39.41992  ? 121 ASN B CA  1 
ATOM   5316 C C   . ASN B 1 122 ? -4.08832  3.97199   -3.72301  1.000 42.78851  ? 121 ASN B C   1 
ATOM   5317 O O   . ASN B 1 122 ? -3.07119  3.30853   -3.94811  1.000 45.21152  ? 121 ASN B O   1 
ATOM   5318 C CB  . ASN B 1 122 ? -6.36543  2.99284   -3.71566  1.000 38.45166  ? 121 ASN B CB  1 
ATOM   5319 C CG  . ASN B 1 122 ? -7.36079  2.15754   -2.97324  1.000 40.88882  ? 121 ASN B CG  1 
ATOM   5320 O OD1 . ASN B 1 122 ? -7.04188  1.55108   -1.94863  1.000 45.96507  ? 121 ASN B OD1 1 
ATOM   5321 N ND2 . ASN B 1 122 ? -8.58361  2.11370   -3.48233  1.000 41.42979  ? 121 ASN B ND2 1 
ATOM   5322 N N   . THR B 1 123 ? -4.27719  5.19422   -4.22880  1.000 43.67947  ? 122 THR B N   1 
ATOM   5323 C CA  . THR B 1 123 ? -3.25726  5.84084   -5.04738  1.000 39.99532  ? 122 THR B CA  1 
ATOM   5324 C C   . THR B 1 123 ? -1.92791  5.92067   -4.31605  1.000 42.05882  ? 122 THR B C   1 
ATOM   5325 O O   . THR B 1 123 ? -0.87171  5.60831   -4.89122  1.000 42.37888  ? 122 THR B O   1 
ATOM   5326 C CB  . THR B 1 123 ? -3.71639  7.23880   -5.44755  1.000 40.73381  ? 122 THR B CB  1 
ATOM   5327 O OG1 . THR B 1 123 ? -4.98704  7.16536   -6.11517  1.000 42.46643  ? 122 THR B OG1 1 
ATOM   5328 C CG2 . THR B 1 123 ? -2.68726  7.87957   -6.35483  1.000 37.05387  ? 122 THR B CG2 1 
ATOM   5329 N N   . ALA B 1 124 ? -1.96756  6.34229   -3.03974  1.000 40.78905  ? 123 ALA B N   1 
ATOM   5330 C CA  . ALA B 1 124 ? -0.74845  6.51551   -2.24602  1.000 41.91062  ? 123 ALA B CA  1 
ATOM   5331 C C   . ALA B 1 124 ? 0.03489   5.21287   -2.12295  1.000 48.33733  ? 123 ALA B C   1 
ATOM   5332 O O   . ALA B 1 124 ? 1.27621   5.21205   -2.16658  1.000 43.88945  ? 123 ALA B O   1 
ATOM   5333 C CB  . ALA B 1 124 ? -1.10175  7.04258   -0.85955  1.000 42.27699  ? 123 ALA B CB  1 
ATOM   5334 N N   . SER B 1 125 ? -0.68020  4.08900   -1.99623  1.000 44.14702  ? 124 SER B N   1 
ATOM   5335 C CA  . SER B 1 125 ? -0.03010  2.81686   -1.71653  1.000 43.77438  ? 124 SER B CA  1 
ATOM   5336 C C   . SER B 1 125 ? 0.83088   2.35146   -2.87633  1.000 43.30422  ? 124 SER B C   1 
ATOM   5337 O O   . SER B 1 125 ? 1.80337   1.62017   -2.65674  1.000 47.87574  ? 124 SER B O   1 
ATOM   5338 C CB  . SER B 1 125 ? -1.07952  1.76499   -1.39693  1.000 40.74467  ? 124 SER B CB  1 
ATOM   5339 O OG  . SER B 1 125 ? -2.17557  2.38077   -0.75987  1.000 43.90147  ? 124 SER B OG  1 
ATOM   5340 N N   . ILE B 1 126 ? 0.47556   2.73396   -4.10901  1.000 40.90871  ? 125 ILE B N   1 
ATOM   5341 C CA  . ILE B 1 126 ? 1.26028   2.32769   -5.27041  1.000 40.53766  ? 125 ILE B CA  1 
ATOM   5342 C C   . ILE B 1 126 ? 2.71666   2.68300   -5.05153  1.000 42.34133  ? 125 ILE B C   1 
ATOM   5343 O O   . ILE B 1 126 ? 3.61628   1.85337   -5.23195  1.000 38.80511  ? 125 ILE B O   1 
ATOM   5344 C CB  . ILE B 1 126 ? 0.72152   2.99951   -6.53961  1.000 42.44375  ? 125 ILE B CB  1 
ATOM   5345 C CG1 . ILE B 1 126 ? -0.44047  2.23274   -7.10627  1.000 40.37874  ? 125 ILE B CG1 1 
ATOM   5346 C CG2 . ILE B 1 126 ? 1.80835   3.10434   -7.60511  1.000 43.85210  ? 125 ILE B CG2 1 
ATOM   5347 C CD1 . ILE B 1 126 ? -0.81545  2.75445   -8.49468  1.000 40.73242  ? 125 ILE B CD1 1 
ATOM   5348 N N   . SER B 1 127 ? 2.94759   3.91776   -4.59680  1.000 49.15319  ? 126 SER B N   1 
ATOM   5349 C CA  . SER B 1 127 ? 4.27518   4.50320   -4.47136  1.000 49.41011  ? 126 SER B CA  1 
ATOM   5350 C C   . SER B 1 127 ? 4.91988   4.15765   -3.13487  1.000 44.37790  ? 126 SER B C   1 
ATOM   5351 O O   . SER B 1 127 ? 6.03249   3.62237   -3.08642  1.000 44.31194  ? 126 SER B O   1 
ATOM   5352 C CB  . SER B 1 127 ? 4.15850   6.01453   -4.63831  1.000 46.41282  ? 126 SER B CB  1 
ATOM   5353 O OG  . SER B 1 127 ? 3.13654   6.28045   -5.58101  1.000 45.63670  ? 126 SER B OG  1 
ATOM   5354 N N   . MET B 1 128 ? 4.22422   4.44517   -2.03996  1.000 44.63596  ? 127 MET B N   1 
ATOM   5355 C CA  . MET B 1 128 ? 4.82223   4.29070   -0.71657  1.000 52.71929  ? 127 MET B CA  1 
ATOM   5356 C C   . MET B 1 128 ? 5.09136   2.82353   -0.39466  1.000 52.13887  ? 127 MET B C   1 
ATOM   5357 O O   . MET B 1 128 ? 6.20083   2.45419   0.02234   1.000 55.41838  ? 127 MET B O   1 
ATOM   5358 C CB  . MET B 1 128 ? 3.89882   4.91994   0.32538   1.000 52.49799  ? 127 MET B CB  1 
ATOM   5359 C CG  . MET B 1 128 ? 3.45332   6.30852   -0.07682  1.000 48.06660  ? 127 MET B CG  1 
ATOM   5360 S SD  . MET B 1 128 ? 2.65515   7.19462   1.24638   1.000 55.36102  ? 127 MET B SD  1 
ATOM   5361 C CE  . MET B 1 128 ? 1.66518   5.90645   1.99417   1.000 60.24657  ? 127 MET B CE  1 
ATOM   5362 N N   . ASP B 1 129 ? 4.09843   1.96931   -0.60232  1.000 45.79860  ? 128 ASP B N   1 
ATOM   5363 C CA  . ASP B 1 129 ? 4.19531   0.58530   -0.17913  1.000 46.30280  ? 128 ASP B CA  1 
ATOM   5364 C C   . ASP B 1 129 ? 4.81473   -0.32637  -1.22501  1.000 46.31593  ? 128 ASP B C   1 
ATOM   5365 O O   . ASP B 1 129 ? 4.72307   -1.54576  -1.08327  1.000 48.17243  ? 128 ASP B O   1 
ATOM   5366 C CB  . ASP B 1 129 ? 2.81481   0.06923   0.21050   1.000 49.29756  ? 128 ASP B CB  1 
ATOM   5367 C CG  . ASP B 1 129 ? 2.21900   0.84272   1.37978   1.000 62.98480  ? 128 ASP B CG  1 
ATOM   5368 O OD1 . ASP B 1 129 ? 3.00511   1.41782   2.17641   1.000 60.99542  ? 128 ASP B OD1 1 
ATOM   5369 O OD2 . ASP B 1 129 ? 0.96862   0.88356   1.49600   1.000 66.62232  ? 128 ASP B OD2 1 
ATOM   5370 N N   . ARG B 1 130 ? 5.45279   0.21538   -2.24980  1.000 43.72947  ? 129 ARG B N   1 
ATOM   5371 C CA  . ARG B 1 130 ? 6.10454   -0.64033  -3.23292  1.000 40.18151  ? 129 ARG B CA  1 
ATOM   5372 C C   . ARG B 1 130 ? 7.28132   -1.38257  -2.59798  1.000 43.87176  ? 129 ARG B C   1 
ATOM   5373 O O   . ARG B 1 130 ? 8.11502   -0.76125  -1.92284  1.000 49.05247  ? 129 ARG B O   1 
ATOM   5374 C CB  . ARG B 1 130 ? 6.58564   0.17683   -4.43137  1.000 41.42904  ? 129 ARG B CB  1 
ATOM   5375 C CG  . ARG B 1 130 ? 7.77712   -0.46572  -5.12847  1.000 46.22018  ? 129 ARG B CG  1 
ATOM   5376 C CD  . ARG B 1 130 ? 8.12775   0.15636   -6.45757  1.000 49.63761  ? 129 ARG B CD  1 
ATOM   5377 N NE  . ARG B 1 130 ? 7.28422   -0.35376  -7.52883  1.000 50.78482  ? 129 ARG B NE  1 
ATOM   5378 C CZ  . ARG B 1 130 ? 7.29874   0.10794   -8.76943  1.000 45.22173  ? 129 ARG B CZ  1 
ATOM   5379 N NH1 . ARG B 1 130 ? 8.17452   1.02291   -9.15173  1.000 40.38169  ? 129 ARG B NH1 1 
ATOM   5380 N NH2 . ARG B 1 130 ? 6.40975   -0.35786  -9.64417  1.000 44.90715  ? 129 ARG B NH2 1 
ATOM   5381 N N   . PRO B 1 131 ? 7.38324   -2.69911  -2.78253  1.000 41.33649  ? 130 PRO B N   1 
ATOM   5382 C CA  . PRO B 1 131 ? 8.55484   -3.43680  -2.28827  1.000 47.76678  ? 130 PRO B CA  1 
ATOM   5383 C C   . PRO B 1 131 ? 9.85482   -2.93892  -2.89929  1.000 51.17898  ? 130 PRO B C   1 
ATOM   5384 O O   . PRO B 1 131 ? 9.89492   -2.49579  -4.04476  1.000 56.81829  ? 130 PRO B O   1 
ATOM   5385 C CB  . PRO B 1 131 ? 8.27399   -4.87818  -2.72281  1.000 36.61746  ? 130 PRO B CB  1 
ATOM   5386 C CG  . PRO B 1 131 ? 7.19238   -4.76594  -3.75643  1.000 42.74026  ? 130 PRO B CG  1 
ATOM   5387 C CD  . PRO B 1 131 ? 6.37223   -3.60112  -3.34377  1.000 41.37056  ? 130 PRO B CD  1 
ATOM   5388 N N   . ASP B 1 132 ? 10.94060  -3.05994  -2.13318  1.000 50.00189  ? 131 ASP B N   1 
ATOM   5389 C CA  . ASP B 1 132 ? 12.23577  -2.58043  -2.60054  1.000 46.56710  ? 131 ASP B CA  1 
ATOM   5390 C C   . ASP B 1 132 ? 12.82935  -3.41376  -3.73754  1.000 53.25394  ? 131 ASP B C   1 
ATOM   5391 O O   . ASP B 1 132 ? 13.72671  -2.92416  -4.42909  1.000 60.24702  ? 131 ASP B O   1 
ATOM   5392 C CB  . ASP B 1 132 ? 13.21641  -2.52618  -1.43327  1.000 45.19386  ? 131 ASP B CB  1 
ATOM   5393 C CG  . ASP B 1 132 ? 12.85156  -1.45834  -0.42518  1.000 49.80259  ? 131 ASP B CG  1 
ATOM   5394 O OD1 . ASP B 1 132 ? 11.94570  -0.64031  -0.72414  1.000 55.88664  ? 131 ASP B OD1 1 
ATOM   5395 O OD2 . ASP B 1 132 ? 13.47270  -1.43015  0.65685   1.000 38.92529  ? 131 ASP B OD2 1 
ATOM   5396 N N   . THR B 1 133 ? 12.38335  -4.65573  -3.95244  1.000 50.45339  ? 132 THR B N   1 
ATOM   5397 C CA  . THR B 1 133 ? 12.90508  -5.38631  -5.10509  1.000 50.39142  ? 132 THR B CA  1 
ATOM   5398 C C   . THR B 1 133 ? 12.36160  -4.86116  -6.41718  1.000 54.03704  ? 132 THR B C   1 
ATOM   5399 O O   . THR B 1 133 ? 12.89644  -5.20736  -7.47192  1.000 66.67391  ? 132 THR B O   1 
ATOM   5400 C CB  . THR B 1 133 ? 12.56742  -6.86329  -5.02055  1.000 55.42886  ? 132 THR B CB  1 
ATOM   5401 O OG1 . THR B 1 133 ? 12.59689  -7.25686  -3.65089  1.000 61.41724  ? 132 THR B OG1 1 
ATOM   5402 C CG2 . THR B 1 133 ? 13.58068  -7.69878  -5.83124  1.000 57.88304  ? 132 THR B CG2 1 
ATOM   5403 N N   . ARG B 1 134 ? 11.30240  -4.06651  -6.37348  1.000 53.13362  ? 133 ARG B N   1 
ATOM   5404 C CA  . ARG B 1 134 ? 10.67716  -3.49154  -7.54571  1.000 46.96670  ? 133 ARG B CA  1 
ATOM   5405 C C   . ARG B 1 134 ? 11.16564  -2.08038  -7.82123  1.000 51.35303  ? 133 ARG B C   1 
ATOM   5406 O O   . ARG B 1 134 ? 10.78299  -1.48620  -8.83433  1.000 58.43814  ? 133 ARG B O   1 
ATOM   5407 C CB  . ARG B 1 134 ? 9.16160   -3.50545  -7.37582  1.000 39.46667  ? 133 ARG B CB  1 
ATOM   5408 C CG  . ARG B 1 134 ? 8.57132   -4.85193  -7.63310  1.000 36.04475  ? 133 ARG B CG  1 
ATOM   5409 C CD  . ARG B 1 134 ? 7.08020   -4.78947  -7.47407  1.000 47.55885  ? 133 ARG B CD  1 
ATOM   5410 N NE  . ARG B 1 134 ? 6.52547   -6.03416  -6.95540  1.000 54.29041  ? 133 ARG B NE  1 
ATOM   5411 C CZ  . ARG B 1 134 ? 5.28904   -6.17308  -6.49000  1.000 54.10103  ? 133 ARG B CZ  1 
ATOM   5412 N NH1 . ARG B 1 134 ? 4.46588   -5.14103  -6.38387  1.000 53.24912  ? 133 ARG B NH1 1 
ATOM   5413 N NH2 . ARG B 1 134 ? 4.85933   -7.38253  -6.14359  1.000 56.02968  ? 133 ARG B NH2 1 
ATOM   5414 N N   . ARG B 1 135 ? 11.99952  -1.53281  -6.95177  1.000 51.99700  ? 134 ARG B N   1 
ATOM   5415 C CA  . ARG B 1 135 ? 12.64200  -0.26100  -7.23235  1.000 56.20072  ? 134 ARG B CA  1 
ATOM   5416 C C   . ARG B 1 135 ? 13.83335  -0.48912  -8.15737  1.000 55.98982  ? 134 ARG B C   1 
ATOM   5417 O O   . ARG B 1 135 ? 14.48851  -1.53500  -8.11446  1.000 52.62711  ? 134 ARG B O   1 
ATOM   5418 C CB  . ARG B 1 135 ? 13.07766  0.41406   -5.92953  1.000 51.11434  ? 134 ARG B CB  1 
ATOM   5419 C CG  . ARG B 1 135 ? 11.97682  0.50657   -4.87119  1.000 42.93187  ? 134 ARG B CG  1 
ATOM   5420 C CD  . ARG B 1 135 ? 11.26051  1.80621   -5.00242  1.000 41.98490  ? 134 ARG B CD  1 
ATOM   5421 N NE  . ARG B 1 135 ? 10.31351  2.06336   -3.92890  1.000 43.46899  ? 134 ARG B NE  1 
ATOM   5422 C CZ  . ARG B 1 135 ? 9.20311   2.77163   -4.08803  1.000 42.70896  ? 134 ARG B CZ  1 
ATOM   5423 N NH1 . ARG B 1 135 ? 8.85801   3.25557   -5.26884  1.000 46.27672  ? 134 ARG B NH1 1 
ATOM   5424 N NH2 . ARG B 1 135 ? 8.42081   3.00301   -3.04013  1.000 39.69370  ? 134 ARG B NH2 1 
ATOM   5425 N N   . ILE B 1 136 ? 14.07501  0.47751   -9.03910  1.000 58.69090  ? 135 ILE B N   1 
ATOM   5426 C CA  . ILE B 1 136 ? 15.16828  0.40284   -10.01040 1.000 53.54088  ? 135 ILE B CA  1 
ATOM   5427 C C   . ILE B 1 136 ? 15.73209  1.80268   -10.23370 1.000 57.45128  ? 135 ILE B C   1 
ATOM   5428 O O   . ILE B 1 136 ? 15.02291  2.67217   -10.76494 1.000 57.42846  ? 135 ILE B O   1 
ATOM   5429 C CB  . ILE B 1 136 ? 14.70498  -0.20403  -11.34495 1.000 51.29115  ? 135 ILE B CB  1 
ATOM   5430 C CG1 . ILE B 1 136 ? 14.08726  -1.59406  -11.15138 1.000 54.87769  ? 135 ILE B CG1 1 
ATOM   5431 C CG2 . ILE B 1 136 ? 15.86978  -0.27182  -12.31583 1.000 56.73346  ? 135 ILE B CG2 1 
ATOM   5432 C CD1 . ILE B 1 136 ? 13.41166  -2.16396  -12.39318 1.000 48.08907  ? 135 ILE B CD1 1 
ATOM   5433 N N   . PRO B 1 137 ? 16.99791  2.05917   -9.89507  1.000 56.18070  ? 136 PRO B N   1 
ATOM   5434 C CA  . PRO B 1 137 ? 17.52467  3.42732   -10.00779 1.000 61.53059  ? 136 PRO B CA  1 
ATOM   5435 C C   . PRO B 1 137 ? 17.51800  3.91463   -11.45432 1.000 57.98902  ? 136 PRO B C   1 
ATOM   5436 O O   . PRO B 1 137 ? 17.68323  3.14084   -12.40149 1.000 53.69532  ? 136 PRO B O   1 
ATOM   5437 C CB  . PRO B 1 137 ? 18.95043  3.30414   -9.46109  1.000 55.88430  ? 136 PRO B CB  1 
ATOM   5438 C CG  . PRO B 1 137 ? 19.33617  1.89695   -9.79305  1.000 55.02976  ? 136 PRO B CG  1 
ATOM   5439 C CD  . PRO B 1 137 ? 18.07332  1.06028   -9.76802  1.000 51.27770  ? 136 PRO B CD  1 
ATOM   5440 N N   . ALA B 1 138 ? 17.33778  5.22634   -11.60751 1.000 51.87220  ? 137 ALA B N   1 
ATOM   5441 C CA  . ALA B 1 138 ? 16.96854  5.78329   -12.90306 1.000 52.41902  ? 137 ALA B CA  1 
ATOM   5442 C C   . ALA B 1 138 ? 17.92277  5.36612   -14.00751 1.000 56.70653  ? 137 ALA B C   1 
ATOM   5443 O O   . ALA B 1 138 ? 17.49382  5.13583   -15.14467 1.000 58.38894  ? 137 ALA B O   1 
ATOM   5444 C CB  . ALA B 1 138 ? 16.90104  7.30459   -12.82335 1.000 58.38571  ? 137 ALA B CB  1 
ATOM   5445 N N   . ALA B 1 139 ? 19.21913  5.25607   -13.70030 1.000 57.20307  ? 138 ALA B N   1 
ATOM   5446 C CA  . ALA B 1 139 ? 20.17930  4.91872   -14.74950 1.000 54.34872  ? 138 ALA B CA  1 
ATOM   5447 C C   . ALA B 1 139 ? 20.04927  3.46233   -15.17588 1.000 53.01555  ? 138 ALA B C   1 
ATOM   5448 O O   . ALA B 1 139 ? 20.21504  3.14287   -16.35581 1.000 53.27658  ? 138 ALA B O   1 
ATOM   5449 C CB  . ALA B 1 139 ? 21.60256  5.22413   -14.29629 1.000 50.82784  ? 138 ALA B CB  1 
ATOM   5450 N N   . GLU B 1 140 ? 19.74984  2.56121   -14.23913 1.000 60.90355  ? 139 GLU B N   1 
ATOM   5451 C CA  . GLU B 1 140 ? 19.42144  1.19264   -14.63212 1.000 60.04069  ? 139 GLU B CA  1 
ATOM   5452 C C   . GLU B 1 140 ? 18.21473  1.18079   -15.56097 1.000 56.53797  ? 139 GLU B C   1 
ATOM   5453 O O   . GLU B 1 140 ? 18.21721  0.51590   -16.60365 1.000 52.67242  ? 139 GLU B O   1 
ATOM   5454 C CB  . GLU B 1 140 ? 19.15938  0.33865   -13.39370 1.000 59.36846  ? 139 GLU B CB  1 
ATOM   5455 C CG  . GLU B 1 140 ? 20.40229  -0.00265  -12.60013 1.000 63.80514  ? 139 GLU B CG  1 
ATOM   5456 C CD  . GLU B 1 140 ? 20.51139  -1.48043  -12.36525 1.000 78.17939  ? 139 GLU B CD  1 
ATOM   5457 O OE1 . GLU B 1 140 ? 19.44809  -2.10514  -12.14922 1.000 79.44275  ? 139 GLU B OE1 1 
ATOM   5458 O OE2 . GLU B 1 140 ? 21.64409  -2.01827  -12.41873 1.000 87.58430  ? 139 GLU B OE2 1 
ATOM   5459 N N   . LEU B 1 141 ? 17.17649  1.93326   -15.19830 1.000 56.54990  ? 140 LEU B N   1 
ATOM   5460 C CA  . LEU B 1 141 ? 16.00287  2.05273   -16.05108 1.000 51.91943  ? 140 LEU B CA  1 
ATOM   5461 C C   . LEU B 1 141 ? 16.37069  2.58814   -17.42836 1.000 52.15729  ? 140 LEU B C   1 
ATOM   5462 O O   . LEU B 1 141 ? 15.98715  2.01550   -18.45021 1.000 57.40682  ? 140 LEU B O   1 
ATOM   5463 C CB  . LEU B 1 141 ? 14.98516  2.96591   -15.38497 1.000 51.42289  ? 140 LEU B CB  1 
ATOM   5464 C CG  . LEU B 1 141 ? 13.77267  2.38040   -14.68978 1.000 46.45544  ? 140 LEU B CG  1 
ATOM   5465 C CD1 . LEU B 1 141 ? 12.72624  3.48210   -14.69777 1.000 45.37650  ? 140 LEU B CD1 1 
ATOM   5466 C CD2 . LEU B 1 141 ? 13.27577  1.12440   -15.38174 1.000 37.55977  ? 140 LEU B CD2 1 
ATOM   5467 N N   . ALA B 1 142 ? 17.12684  3.68323   -17.47742 1.000 51.47319  ? 141 ALA B N   1 
ATOM   5468 C CA  . ALA B 1 142 ? 17.36010  4.38531   -18.73658 1.000 50.72913  ? 141 ALA B CA  1 
ATOM   5469 C C   . ALA B 1 142 ? 17.98782  3.50934   -19.82086 1.000 51.19003  ? 141 ALA B C   1 
ATOM   5470 O O   . ALA B 1 142 ? 17.98965  3.90282   -20.99468 1.000 61.42787  ? 141 ALA B O   1 
ATOM   5471 C CB  . ALA B 1 142 ? 18.23306  5.61637   -18.48624 1.000 53.64856  ? 141 ALA B CB  1 
ATOM   5472 N N   . VAL B 1 143 ? 18.51225  2.34184   -19.47411 1.000 48.58105  ? 142 VAL B N   1 
ATOM   5473 C CA  . VAL B 1 143 ? 18.96659  1.37390   -20.46072 1.000 51.24008  ? 142 VAL B CA  1 
ATOM   5474 C C   . VAL B 1 143 ? 18.11001  0.11010   -20.42348 1.000 49.42347  ? 142 VAL B C   1 
ATOM   5475 O O   . VAL B 1 143 ? 18.41471  -0.87529  -21.10899 1.000 45.97586  ? 142 VAL B O   1 
ATOM   5476 C CB  . VAL B 1 143 ? 20.46579  1.06440   -20.27363 1.000 46.79810  ? 142 VAL B CB  1 
ATOM   5477 C CG1 . VAL B 1 143 ? 20.68998  0.13251   -19.08564 1.000 44.62403  ? 142 VAL B CG1 1 
ATOM   5478 C CG2 . VAL B 1 143 ? 21.09544  0.51505   -21.55535 1.000 47.78155  ? 142 VAL B CG2 1 
ATOM   5479 N N   . ALA B 1 144 ? 17.03638  0.12007   -19.63368 1.000 50.92201  ? 143 ALA B N   1 
ATOM   5480 C CA  . ALA B 1 144 ? 16.09596  -0.98548  -19.56178 1.000 47.16187  ? 143 ALA B CA  1 
ATOM   5481 C C   . ALA B 1 144 ? 15.14011  -0.92230  -20.74773 1.000 54.71699  ? 143 ALA B C   1 
ATOM   5482 O O   . ALA B 1 144 ? 15.16884  0.01296   -21.55714 1.000 56.37347  ? 143 ALA B O   1 
ATOM   5483 C CB  . ALA B 1 144 ? 15.33443  -0.95167  -18.24137 1.000 45.41725  ? 143 ALA B CB  1 
ATOM   5484 N N   . ASP B 1 145 ? 14.26206  -1.90974  -20.85651 1.000 50.63440  ? 144 ASP B N   1 
ATOM   5485 C CA  . ASP B 1 145 ? 13.46975  -2.01773  -22.06595 1.000 48.09002  ? 144 ASP B CA  1 
ATOM   5486 C C   . ASP B 1 145 ? 11.97813  -1.78446  -21.80264 1.000 46.91793  ? 144 ASP B C   1 
ATOM   5487 O O   . ASP B 1 145 ? 11.54488  -1.50827  -20.67740 1.000 48.46275  ? 144 ASP B O   1 
ATOM   5488 C CB  . ASP B 1 145 ? 13.75722  -3.35447  -22.74667 1.000 55.72664  ? 144 ASP B CB  1 
ATOM   5489 C CG  . ASP B 1 145 ? 13.07580  -4.51783  -22.09777 1.000 54.02072  ? 144 ASP B CG  1 
ATOM   5490 O OD1 . ASP B 1 145 ? 12.32034  -4.34345  -21.11029 1.000 52.57404  ? 144 ASP B OD1 1 
ATOM   5491 O OD2 . ASP B 1 145 ? 13.33074  -5.63538  -22.60356 1.000 59.12522  ? 144 ASP B OD2 1 
ATOM   5492 N N   . PHE B 1 146 ? 11.20363  -1.95083  -22.87795 1.000 43.28698  ? 145 PHE B N   1 
ATOM   5493 C CA  . PHE B 1 146 ? 9.87363   -1.35807  -23.01703 1.000 39.86861  ? 145 PHE B CA  1 
ATOM   5494 C C   . PHE B 1 146 ? 8.96325   -1.73028  -21.85720 1.000 40.00779  ? 145 PHE B C   1 
ATOM   5495 O O   . PHE B 1 146 ? 8.41082   -0.85917  -21.17792 1.000 37.31353  ? 145 PHE B O   1 
ATOM   5496 C CB  . PHE B 1 146 ? 9.27970   -1.81843  -24.35343 1.000 39.11958  ? 145 PHE B CB  1 
ATOM   5497 C CG  . PHE B 1 146 ? 7.93596   -1.25868  -24.67087 1.000 34.15318  ? 145 PHE B CG  1 
ATOM   5498 C CD1 . PHE B 1 146 ? 7.54283   -0.02506  -24.19821 1.000 38.28076  ? 145 PHE B CD1 1 
ATOM   5499 C CD2 . PHE B 1 146 ? 7.07479   -1.96549  -25.48878 1.000 35.71339  ? 145 PHE B CD2 1 
ATOM   5500 C CE1 . PHE B 1 146 ? 6.29924   0.47711   -24.51409 1.000 41.08569  ? 145 PHE B CE1 1 
ATOM   5501 C CE2 . PHE B 1 146 ? 5.83886   -1.46513  -25.82366 1.000 36.43443  ? 145 PHE B CE2 1 
ATOM   5502 C CZ  . PHE B 1 146 ? 5.44765   -0.24645  -25.33289 1.000 42.52664  ? 145 PHE B CZ  1 
ATOM   5503 N N   . GLN B 1 147 ? 8.78370   -3.02667  -21.62178 1.000 39.04735  ? 146 GLN B N   1 
ATOM   5504 C CA  . GLN B 1 147 ? 7.84095   -3.43909  -20.60278 1.000 34.58728  ? 146 GLN B CA  1 
ATOM   5505 C C   . GLN B 1 147 ? 8.40301   -3.28384  -19.19510 1.000 41.83047  ? 146 GLN B C   1 
ATOM   5506 O O   . GLN B 1 147 ? 7.63495   -3.23640  -18.22825 1.000 39.63318  ? 146 GLN B O   1 
ATOM   5507 C CB  . GLN B 1 147 ? 7.41632   -4.87133  -20.86934 1.000 32.85931  ? 146 GLN B CB  1 
ATOM   5508 C CG  . GLN B 1 147 ? 6.44223   -4.99812  -22.01981 1.000 34.92710  ? 146 GLN B CG  1 
ATOM   5509 C CD  . GLN B 1 147 ? 5.20461   -4.14417  -21.83604 1.000 40.33036  ? 146 GLN B CD  1 
ATOM   5510 O OE1 . GLN B 1 147 ? 5.00201   -3.15673  -22.54419 1.000 44.21015  ? 146 GLN B OE1 1 
ATOM   5511 N NE2 . GLN B 1 147 ? 4.36490   -4.51955  -20.87817 1.000 41.84720  ? 146 GLN B NE2 1 
ATOM   5512 N N   . THR B 1 148 ? 9.72041   -3.18171  -19.05162 1.000 42.15759  ? 147 THR B N   1 
ATOM   5513 C CA  . THR B 1 148 ? 10.27198  -2.90192  -17.73587 1.000 42.21359  ? 147 THR B CA  1 
ATOM   5514 C C   . THR B 1 148 ? 10.00608  -1.45313  -17.32614 1.000 43.76126  ? 147 THR B C   1 
ATOM   5515 O O   . THR B 1 148 ? 9.60060   -1.19142  -16.18965 1.000 48.63213  ? 147 THR B O   1 
ATOM   5516 C CB  . THR B 1 148 ? 11.76354  -3.23098  -17.71557 1.000 44.10754  ? 147 THR B CB  1 
ATOM   5517 O OG1 . THR B 1 148 ? 11.93184  -4.64294  -17.85231 1.000 45.59166  ? 147 THR B OG1 1 
ATOM   5518 C CG2 . THR B 1 148 ? 12.37456  -2.80796  -16.40263 1.000 42.54300  ? 147 THR B CG2 1 
ATOM   5519 N N   . ILE B 1 149 ? 10.22466  -0.49257  -18.23289 1.000 41.81850  ? 148 ILE B N   1 
ATOM   5520 C CA  . ILE B 1 149 ? 9.86283   0.89052   -17.92678 1.000 38.56038  ? 148 ILE B CA  1 
ATOM   5521 C C   . ILE B 1 149 ? 8.36852   0.99599   -17.69025 1.000 40.23904  ? 148 ILE B C   1 
ATOM   5522 O O   . ILE B 1 149 ? 7.90149   1.88965   -16.97855 1.000 45.89656  ? 148 ILE B O   1 
ATOM   5523 C CB  . ILE B 1 149 ? 10.29957  1.84315   -19.05643 1.000 39.03752  ? 148 ILE B CB  1 
ATOM   5524 C CG1 . ILE B 1 149 ? 11.66226  1.46296   -19.60230 1.000 39.75457  ? 148 ILE B CG1 1 
ATOM   5525 C CG2 . ILE B 1 149 ? 10.32641  3.28743   -18.59561 1.000 36.75386  ? 148 ILE B CG2 1 
ATOM   5526 C CD1 . ILE B 1 149 ? 12.02128  2.32352   -20.76997 1.000 44.54285  ? 148 ILE B CD1 1 
ATOM   5527 N N   . GLU B 1 150 ? 7.59227   0.09854   -18.28243 1.000 38.62063  ? 149 GLU B N   1 
ATOM   5528 C CA  . GLU B 1 150 ? 6.14783   0.17864   -18.12999 1.000 40.60217  ? 149 GLU B CA  1 
ATOM   5529 C C   . GLU B 1 150 ? 5.74348   -0.15332  -16.70462 1.000 40.00962  ? 149 GLU B C   1 
ATOM   5530 O O   . GLU B 1 150 ? 5.06159   0.63533   -16.04228 1.000 41.51376  ? 149 GLU B O   1 
ATOM   5531 C CB  . GLU B 1 150 ? 5.46351   -0.75018  -19.14325 1.000 43.01007  ? 149 GLU B CB  1 
ATOM   5532 C CG  . GLU B 1 150 ? 3.98864   -0.45835  -19.40003 1.000 42.21819  ? 149 GLU B CG  1 
ATOM   5533 C CD  . GLU B 1 150 ? 3.76124   0.78971   -20.26021 1.000 54.85965  ? 149 GLU B CD  1 
ATOM   5534 O OE1 . GLU B 1 150 ? 4.72549   1.22404   -20.96365 1.000 55.76961  ? 149 GLU B OE1 1 
ATOM   5535 O OE2 . GLU B 1 150 ? 2.61563   1.33339   -20.21813 1.000 46.70810  ? 149 GLU B OE2 1 
ATOM   5536 N N   . LYS B 1 151 ? 6.18980   -1.30346  -16.19901 1.000 44.32503  ? 150 LYS B N   1 
ATOM   5537 C CA  . LYS B 1 151 ? 5.81789   -1.71013  -14.84939 1.000 41.22342  ? 150 LYS B CA  1 
ATOM   5538 C C   . LYS B 1 151 ? 6.39072   -0.79381  -13.77804 1.000 42.41047  ? 150 LYS B C   1 
ATOM   5539 O O   . LYS B 1 151 ? 5.82331   -0.72212  -12.68483 1.000 46.14873  ? 150 LYS B O   1 
ATOM   5540 C CB  . LYS B 1 151 ? 6.24538   -3.15380  -14.58757 1.000 38.95984  ? 150 LYS B CB  1 
ATOM   5541 C CG  . LYS B 1 151 ? 7.73063   -3.46204  -14.67958 1.000 36.54739  ? 150 LYS B CG  1 
ATOM   5542 C CD  . LYS B 1 151 ? 7.89841   -4.97713  -14.61625 1.000 41.48741  ? 150 LYS B CD  1 
ATOM   5543 C CE  . LYS B 1 151 ? 9.34693   -5.43082  -14.59285 1.000 48.38373  ? 150 LYS B CE  1 
ATOM   5544 N NZ  . LYS B 1 151 ? 9.54258   -6.66224  -15.43908 1.000 58.41790  ? 150 LYS B NZ  1 
ATOM   5545 N N   . THR B 1 152 ? 7.46863   -0.06570  -14.07292 1.000 42.28250  ? 151 THR B N   1 
ATOM   5546 C CA  . THR B 1 152 ? 8.15102   0.72838   -13.06059 1.000 39.83452  ? 151 THR B CA  1 
ATOM   5547 C C   . THR B 1 152 ? 7.47342   2.06413   -12.78693 1.000 42.23294  ? 151 THR B C   1 
ATOM   5548 O O   . THR B 1 152 ? 7.69034   2.63340   -11.71467 1.000 39.92107  ? 151 THR B O   1 
ATOM   5549 C CB  . THR B 1 152 ? 9.60368   0.93555   -13.48753 1.000 40.61448  ? 151 THR B CB  1 
ATOM   5550 O OG1 . THR B 1 152 ? 10.28643  -0.31554  -13.38778 1.000 45.21764  ? 151 THR B OG1 1 
ATOM   5551 C CG2 . THR B 1 152 ? 10.31834  1.94856   -12.61880 1.000 33.12593  ? 151 THR B CG2 1 
ATOM   5552 N N   . MET B 1 153 ? 6.64259   2.56817   -13.70149 1.000 40.07151  ? 152 MET B N   1 
ATOM   5553 C CA  . MET B 1 153 ? 6.00909   3.86337   -13.47573 1.000 37.85134  ? 152 MET B CA  1 
ATOM   5554 C C   . MET B 1 153 ? 5.10710   3.82833   -12.24367 1.000 46.15063  ? 152 MET B C   1 
ATOM   5555 O O   . MET B 1 153 ? 4.42940   2.83419   -11.97296 1.000 53.03195  ? 152 MET B O   1 
ATOM   5556 C CB  . MET B 1 153 ? 5.18557   4.28952   -14.69005 1.000 39.97046  ? 152 MET B CB  1 
ATOM   5557 C CG  . MET B 1 153 ? 5.89326   4.34505   -16.02865 1.000 39.50523  ? 152 MET B CG  1 
ATOM   5558 S SD  . MET B 1 153 ? 7.06106   5.69669   -16.10717 1.000 44.63845  ? 152 MET B SD  1 
ATOM   5559 C CE  . MET B 1 153 ? 8.59995   4.87041   -15.63788 1.000 38.94248  ? 152 MET B CE  1 
ATOM   5560 N N   . THR B 1 154 ? 5.09352   4.92819   -11.49216 1.000 43.37896  ? 153 THR B N   1 
ATOM   5561 C CA  . THR B 1 154 ? 4.22772   5.05574   -10.32904 1.000 42.34943  ? 153 THR B CA  1 
ATOM   5562 C C   . THR B 1 154 ? 3.51171   6.39115   -10.24982 1.000 45.04686  ? 153 THR B C   1 
ATOM   5563 O O   . THR B 1 154 ? 2.65656   6.55634   -9.37389  1.000 49.68886  ? 153 THR B O   1 
ATOM   5564 C CB  . THR B 1 154 ? 5.02707   4.87091   -9.03152  1.000 46.77707  ? 153 THR B CB  1 
ATOM   5565 O OG1 . THR B 1 154 ? 6.08754   5.83920   -8.98939  1.000 47.32678  ? 153 THR B OG1 1 
ATOM   5566 C CG2 . THR B 1 154 ? 5.59673   3.45553   -8.93930  1.000 43.92274  ? 153 THR B CG2 1 
ATOM   5567 N N   . GLU B 1 155 ? 3.83878   7.34833   -11.11337 1.000 36.37661  ? 154 GLU B N   1 
ATOM   5568 C CA  . GLU B 1 155 ? 3.27884   8.68125   -11.00447 1.000 29.99529  ? 154 GLU B CA  1 
ATOM   5569 C C   . GLU B 1 155 ? 1.89602   8.78881   -11.62397 1.000 33.86921  ? 154 GLU B C   1 
ATOM   5570 O O   . GLU B 1 155 ? 1.13177   9.68000   -11.24875 1.000 36.36431  ? 154 GLU B O   1 
ATOM   5571 C CB  . GLU B 1 155 ? 4.22691   9.67997   -11.65988 1.000 33.34939  ? 154 GLU B CB  1 
ATOM   5572 C CG  . GLU B 1 155 ? 5.57129   9.83876   -10.96311 1.000 36.26316  ? 154 GLU B CG  1 
ATOM   5573 C CD  . GLU B 1 155 ? 6.62067   8.85919   -11.46473 1.000 48.20726  ? 154 GLU B CD  1 
ATOM   5574 O OE1 . GLU B 1 155 ? 6.24625   7.89156   -12.16861 1.000 48.56840  ? 154 GLU B OE1 1 
ATOM   5575 O OE2 . GLU B 1 155 ? 7.82246   9.05328   -11.15649 1.000 47.74179  ? 154 GLU B OE2 1 
ATOM   5576 N N   . GLY B 1 156 ? 1.55651   7.91404   -12.56356 1.000 41.37988  ? 155 GLY B N   1 
ATOM   5577 C CA  . GLY B 1 156 ? 0.27322   8.04121   -13.23294 1.000 46.17467  ? 155 GLY B CA  1 
ATOM   5578 C C   . GLY B 1 156 ? 0.08221   9.39735   -13.89840 1.000 46.61329  ? 155 GLY B C   1 
ATOM   5579 O O   . GLY B 1 156 ? 1.03711   10.08567  -14.28884 1.000 41.86332  ? 155 GLY B O   1 
ATOM   5580 N N   . HIS B 1 157 ? -1.18069  9.78977   -14.02223 1.000 41.83707  ? 156 HIS B N   1 
ATOM   5581 C CA  . HIS B 1 157 ? -1.50495  11.07231  -14.61830 1.000 42.39544  ? 156 HIS B CA  1 
ATOM   5582 C C   . HIS B 1 157 ? -0.90515  12.19505  -13.78030 1.000 50.10605  ? 156 HIS B C   1 
ATOM   5583 O O   . HIS B 1 157 ? -1.13689  12.24192  -12.56316 1.000 54.95772  ? 156 HIS B O   1 
ATOM   5584 C CB  . HIS B 1 157 ? -3.01587  11.24268  -14.71327 1.000 48.85642  ? 156 HIS B CB  1 
ATOM   5585 C CG  . HIS B 1 157 ? -3.43954  12.35192  -15.62748 1.000 55.13350  ? 156 HIS B CG  1 
ATOM   5586 N ND1 . HIS B 1 157 ? -3.82991  13.59092  -15.16715 1.000 59.23880  ? 156 HIS B ND1 1 
ATOM   5587 C CD2 . HIS B 1 157 ? -3.54221  12.40446  -16.97605 1.000 55.65427  ? 156 HIS B CD2 1 
ATOM   5588 C CE1 . HIS B 1 157 ? -4.15568  14.35874  -16.19201 1.000 57.45574  ? 156 HIS B CE1 1 
ATOM   5589 N NE2 . HIS B 1 157 ? -3.98654  13.66388  -17.30146 1.000 63.71427  ? 156 HIS B NE2 1 
ATOM   5590 N N   . PRO B 1 158 ? -0.13661  13.11319  -14.37507 1.000 51.29344  ? 157 PRO B N   1 
ATOM   5591 C CA  . PRO B 1 158 ? 0.49752   14.16416  -13.56730 1.000 50.39738  ? 157 PRO B CA  1 
ATOM   5592 C C   . PRO B 1 158 ? -0.45110  15.25594  -13.09223 1.000 49.12966  ? 157 PRO B C   1 
ATOM   5593 O O   . PRO B 1 158 ? -0.01594  16.14007  -12.34699 1.000 58.28625  ? 157 PRO B O   1 
ATOM   5594 C CB  . PRO B 1 158 ? 1.57770   14.72512  -14.50661 1.000 43.09151  ? 157 PRO B CB  1 
ATOM   5595 C CG  . PRO B 1 158 ? 1.10341   14.41817  -15.84838 1.000 48.76545  ? 157 PRO B CG  1 
ATOM   5596 C CD  . PRO B 1 158 ? 0.33626   13.13357  -15.76785 1.000 51.16132  ? 157 PRO B CD  1 
ATOM   5597 N N   . CYS B 1 159 ? -1.72972  15.24218  -13.45363 1.000 44.59783  ? 158 CYS B N   1 
ATOM   5598 C CA  . CYS B 1 159 ? -2.62463  16.28980  -12.97875 1.000 47.51088  ? 158 CYS B CA  1 
ATOM   5599 C C   . CYS B 1 159 ? -3.53268  15.78768  -11.86389 1.000 50.34569  ? 158 CYS B C   1 
ATOM   5600 O O   . CYS B 1 159 ? -3.49458  16.32417  -10.75368 1.000 51.40482  ? 158 CYS B O   1 
ATOM   5601 C CB  . CYS B 1 159 ? -3.43875  16.88026  -14.13803 1.000 50.17034  ? 158 CYS B CB  1 
ATOM   5602 S SG  . CYS B 1 159 ? -2.40848  17.58545  -15.49425 1.000 66.91414  ? 158 CYS B SG  1 
ATOM   5603 N N   . LEU B 1 160 ? -4.33905  14.76081  -12.12578 1.000 53.06200  ? 159 LEU B N   1 
ATOM   5604 C CA  . LEU B 1 160 ? -5.17718  14.20464  -11.06865 1.000 50.20473  ? 159 LEU B CA  1 
ATOM   5605 C C   . LEU B 1 160 ? -4.31824  13.73720  -9.90203  1.000 49.79271  ? 159 LEU B C   1 
ATOM   5606 O O   . LEU B 1 160 ? -3.26876  13.11477  -10.09402 1.000 50.38590  ? 159 LEU B O   1 
ATOM   5607 C CB  . LEU B 1 160 ? -6.01189  13.04806  -11.60269 1.000 48.63600  ? 159 LEU B CB  1 
ATOM   5608 C CG  . LEU B 1 160 ? -6.94113  13.42102  -12.74824 1.000 53.69956  ? 159 LEU B CG  1 
ATOM   5609 C CD1 . LEU B 1 160 ? -7.88478  12.27269  -13.00196 1.000 61.87517  ? 159 LEU B CD1 1 
ATOM   5610 C CD2 . LEU B 1 160 ? -7.70866  14.69271  -12.43439 1.000 53.90111  ? 159 LEU B CD2 1 
ATOM   5611 N N   . VAL B 1 161 ? -4.74150  14.05777  -8.68230  1.000 50.24473  ? 160 VAL B N   1 
ATOM   5612 C CA  . VAL B 1 161 ? -3.98905  13.52026  -7.55795  1.000 52.07948  ? 160 VAL B CA  1 
ATOM   5613 C C   . VAL B 1 161 ? -4.48522  12.11556  -7.19601  1.000 49.86800  ? 160 VAL B C   1 
ATOM   5614 O O   . VAL B 1 161 ? -3.66847  11.21329  -6.97366  1.000 43.78235  ? 160 VAL B O   1 
ATOM   5615 C CB  . VAL B 1 161 ? -4.02006  14.49996  -6.36944  1.000 50.60967  ? 160 VAL B CB  1 
ATOM   5616 C CG1 . VAL B 1 161 ? -3.89208  15.91971  -6.87861  1.000 45.61772  ? 160 VAL B CG1 1 
ATOM   5617 C CG2 . VAL B 1 161 ? -5.24909  14.33306  -5.50467  1.000 49.19189  ? 160 VAL B CG2 1 
ATOM   5618 N N   . ALA B 1 162 ? -5.81307  11.88281  -7.20954  1.000 47.91171  ? 161 ALA B N   1 
ATOM   5619 C CA  . ALA B 1 162 ? -6.39649  10.55927  -6.92044  1.000 47.68044  ? 161 ALA B CA  1 
ATOM   5620 C C   . ALA B 1 162 ? -6.57392  9.77867   -8.21848  1.000 46.16601  ? 161 ALA B C   1 
ATOM   5621 O O   . ALA B 1 162 ? -7.68001  9.59882   -8.73355  1.000 50.86477  ? 161 ALA B O   1 
ATOM   5622 C CB  . ALA B 1 162 ? -7.72639  10.68990  -6.18912  1.000 45.84798  ? 161 ALA B CB  1 
ATOM   5623 N N   . ASN B 1 163 ? -5.44459  9.29338   -8.73576  1.000 43.16285  ? 162 ASN B N   1 
ATOM   5624 C CA  . ASN B 1 163 ? -5.37869  8.76676   -10.09175 1.000 42.70926  ? 162 ASN B CA  1 
ATOM   5625 C C   . ASN B 1 163 ? -5.14818  7.25556   -10.13707 1.000 44.68855  ? 162 ASN B C   1 
ATOM   5626 O O   . ASN B 1 163 ? -4.69453  6.73699   -11.15850 1.000 50.11093  ? 162 ASN B O   1 
ATOM   5627 C CB  . ASN B 1 163 ? -4.29481  9.51275   -10.87865 1.000 40.04103  ? 162 ASN B CB  1 
ATOM   5628 C CG  . ASN B 1 163 ? -2.87097  9.21265   -10.38489 1.000 43.06428  ? 162 ASN B CG  1 
ATOM   5629 O OD1 . ASN B 1 163 ? -2.66311  8.36360   -9.52701  1.000 47.92625  ? 162 ASN B OD1 1 
ATOM   5630 N ND2 . ASN B 1 163 ? -1.88314  9.89263   -10.96288 1.000 39.85684  ? 162 ASN B ND2 1 
ATOM   5631 N N   . ALA B 1 164 ? -5.44641  6.53623   -9.05723  1.000 38.34071  ? 163 ALA B N   1 
ATOM   5632 C CA  . ALA B 1 164 ? -5.17338  5.10632   -9.01867  1.000 36.09981  ? 163 ALA B CA  1 
ATOM   5633 C C   . ALA B 1 164 ? -6.09244  4.41423   -8.01966  1.000 41.39975  ? 163 ALA B C   1 
ATOM   5634 O O   . ALA B 1 164 ? -5.66582  3.52823   -7.26843  1.000 37.93594  ? 163 ALA B O   1 
ATOM   5635 C CB  . ALA B 1 164 ? -3.70756  4.84979   -8.67792  1.000 31.10514  ? 163 ALA B CB  1 
ATOM   5636 N N   . GLY B 1 165 ? -7.35834  4.82031   -7.99863  1.000 43.13600  ? 164 GLY B N   1 
ATOM   5637 C CA  . GLY B 1 165 ? -8.33251  4.15957   -7.15674  1.000 42.30999  ? 164 GLY B CA  1 
ATOM   5638 C C   . GLY B 1 165 ? -8.39930  2.66228   -7.38941  1.000 44.18646  ? 164 GLY B C   1 
ATOM   5639 O O   . GLY B 1 165 ? -8.18372  1.87484   -6.46364  1.000 42.94129  ? 164 GLY B O   1 
ATOM   5640 N N   . ARG B 1 166 ? -8.65550  2.25818   -8.63392  1.000 45.54544  ? 165 ARG B N   1 
ATOM   5641 C CA  . ARG B 1 166 ? -8.88716  0.86064   -8.96445  1.000 35.73993  ? 165 ARG B CA  1 
ATOM   5642 C C   . ARG B 1 166 ? -9.92244  0.27626   -8.01343  1.000 39.10211  ? 165 ARG B C   1 
ATOM   5643 O O   . ARG B 1 166 ? -9.70739  -0.74506  -7.35615  1.000 38.71557  ? 165 ARG B O   1 
ATOM   5644 C CB  . ARG B 1 166 ? -7.58358  0.06695   -8.94373  1.000 35.96741  ? 165 ARG B CB  1 
ATOM   5645 C CG  . ARG B 1 166 ? -6.65805  0.42625   -10.08923 1.000 35.19677  ? 165 ARG B CG  1 
ATOM   5646 C CD  . ARG B 1 166 ? -5.68168  1.46889   -9.63456  1.000 39.10282  ? 165 ARG B CD  1 
ATOM   5647 N NE  . ARG B 1 166 ? -4.55904  1.63797   -10.54369 1.000 40.35112  ? 165 ARG B NE  1 
ATOM   5648 C CZ  . ARG B 1 166 ? -3.41821  0.96335   -10.47450 1.000 36.23198  ? 165 ARG B CZ  1 
ATOM   5649 N NH1 . ARG B 1 166 ? -3.22057  0.01507   -9.57329  1.000 37.06029  ? 165 ARG B NH1 1 
ATOM   5650 N NH2 . ARG B 1 166 ? -2.45475  1.23458   -11.34485 1.000 40.66621  ? 165 ARG B NH2 1 
ATOM   5651 N N   . LEU B 1 167 ? -11.05358 0.97137   -7.92317  1.000 43.43367  ? 166 LEU B N   1 
ATOM   5652 C CA  . LEU B 1 167 ? -12.19313 0.50139   -7.14407  1.000 40.03488  ? 166 LEU B CA  1 
ATOM   5653 C C   . LEU B 1 167 ? -12.77820 -0.74741  -7.78404  1.000 39.56610  ? 166 LEU B C   1 
ATOM   5654 O O   . LEU B 1 167 ? -13.16715 -0.72472  -8.95801  1.000 42.51567  ? 166 LEU B O   1 
ATOM   5655 C CB  . LEU B 1 167 ? -13.25847 1.58570   -7.05556  1.000 45.03509  ? 166 LEU B CB  1 
ATOM   5656 C CG  . LEU B 1 167 ? -12.79012 2.93437   -6.54526  1.000 47.60999  ? 166 LEU B CG  1 
ATOM   5657 C CD1 . LEU B 1 167 ? -14.00462 3.72676   -6.12554  1.000 51.75254  ? 166 LEU B CD1 1 
ATOM   5658 C CD2 . LEU B 1 167 ? -11.80737 2.74199   -5.39557  1.000 43.05842  ? 166 LEU B CD2 1 
ATOM   5659 N N   . GLY B 1 168 ? -12.87162 -1.82056  -6.99329  1.000 40.93477  ? 167 GLY B N   1 
ATOM   5660 C CA  . GLY B 1 168 ? -13.21302 -3.15388  -7.46255  1.000 33.98831  ? 167 GLY B CA  1 
ATOM   5661 C C   . GLY B 1 168 ? -12.08237 -4.14205  -7.26872  1.000 33.55376  ? 167 GLY B C   1 
ATOM   5662 O O   . GLY B 1 168 ? -12.32745 -5.32493  -6.98929  1.000 34.58711  ? 167 GLY B O   1 
ATOM   5663 N N   . PHE B 1 169 ? -10.84901 -3.67039  -7.38314  1.000 30.30873  ? 168 PHE B N   1 
ATOM   5664 C CA  . PHE B 1 169 ? -9.69502  -4.51984  -7.18559  1.000 35.05267  ? 168 PHE B CA  1 
ATOM   5665 C C   . PHE B 1 169 ? -9.48689  -4.75523  -5.69583  1.000 41.36350  ? 168 PHE B C   1 
ATOM   5666 O O   . PHE B 1 169 ? -9.51319  -3.81813  -4.88531  1.000 40.15745  ? 168 PHE B O   1 
ATOM   5667 C CB  . PHE B 1 169 ? -8.45682  -3.88143  -7.80863  1.000 39.33924  ? 168 PHE B CB  1 
ATOM   5668 C CG  . PHE B 1 169 ? -8.21200  -4.30016  -9.22085  1.000 37.56640  ? 168 PHE B CG  1 
ATOM   5669 C CD1 . PHE B 1 169 ? -9.19719  -4.94701  -9.94272  1.000 36.14258  ? 168 PHE B CD1 1 
ATOM   5670 C CD2 . PHE B 1 169 ? -6.99267  -4.05317  -9.82788  1.000 39.24581  ? 168 PHE B CD2 1 
ATOM   5671 C CE1 . PHE B 1 169 ? -8.96925  -5.34131  -11.24955 1.000 34.40993  ? 168 PHE B CE1 1 
ATOM   5672 C CE2 . PHE B 1 169 ? -6.76159  -4.44890  -11.14258 1.000 38.78192  ? 168 PHE B CE2 1 
ATOM   5673 C CZ  . PHE B 1 169 ? -7.75072  -5.09337  -11.84621 1.000 33.55792  ? 168 PHE B CZ  1 
ATOM   5674 N N   . SER B 1 170 ? -9.31810  -6.01496  -5.33729  1.000 41.30621  ? 169 SER B N   1 
ATOM   5675 C CA  . SER B 1 170 ? -8.92945  -6.38423  -3.99216  1.000 36.70368  ? 169 SER B CA  1 
ATOM   5676 C C   . SER B 1 170 ? -7.41828  -6.22539  -3.86759  1.000 41.85172  ? 169 SER B C   1 
ATOM   5677 O O   . SER B 1 170 ? -6.73116  -5.74242  -4.77297  1.000 41.05951  ? 169 SER B O   1 
ATOM   5678 C CB  . SER B 1 170 ? -9.33055  -7.81658  -3.71298  1.000 37.02499  ? 169 SER B CB  1 
ATOM   5679 O OG  . SER B 1 170 ? -8.37242  -8.65054  -4.34758  1.000 38.44802  ? 169 SER B OG  1 
ATOM   5680 N N   . ALA B 1 171 ? -6.88193  -6.69078  -2.74458  1.000 43.12044  ? 170 ALA B N   1 
ATOM   5681 C CA  . ALA B 1 171 ? -5.44997  -6.62324  -2.50555  1.000 37.80018  ? 170 ALA B CA  1 
ATOM   5682 C C   . ALA B 1 171 ? -4.68106  -7.58958  -3.39366  1.000 42.62651  ? 170 ALA B C   1 
ATOM   5683 O O   . ALA B 1 171 ? -3.53853  -7.29352  -3.77428  1.000 40.86783  ? 170 ALA B O   1 
ATOM   5684 C CB  . ALA B 1 171 ? -5.17540  -6.91529  -1.03471  1.000 44.13249  ? 170 ALA B CB  1 
ATOM   5685 N N   . ASP B 1 172 ? -5.28078  -8.75418  -3.71075  1.000 44.86406  ? 171 ASP B N   1 
ATOM   5686 C CA  . ASP B 1 172 ? -4.68421  -9.70326  -4.65231  1.000 43.87324  ? 171 ASP B CA  1 
ATOM   5687 C C   . ASP B 1 172 ? -4.91155  -9.27074  -6.09394  1.000 48.28745  ? 171 ASP B C   1 
ATOM   5688 O O   . ASP B 1 172 ? -4.04742  -9.48789  -6.95177  1.000 46.34617  ? 171 ASP B O   1 
ATOM   5689 C CB  . ASP B 1 172 ? -5.25770  -11.10854 -4.46829  1.000 47.18773  ? 171 ASP B CB  1 
ATOM   5690 C CG  . ASP B 1 172 ? -5.59031  -11.42427 -3.03815  1.000 58.51417  ? 171 ASP B CG  1 
ATOM   5691 O OD1 . ASP B 1 172 ? -4.71130  -11.20923 -2.16696  1.000 63.83834  ? 171 ASP B OD1 1 
ATOM   5692 O OD2 . ASP B 1 172 ? -6.73342  -11.89351 -2.79099  1.000 59.84552  ? 171 ASP B OD2 1 
ATOM   5693 N N   . ASP B 1 173 ? -6.08320  -8.69275  -6.38451  1.000 43.07240  ? 172 ASP B N   1 
ATOM   5694 C CA  . ASP B 1 173 ? -6.31457  -8.15346  -7.71410  1.000 37.45552  ? 172 ASP B CA  1 
ATOM   5695 C C   . ASP B 1 173 ? -5.24393  -7.13409  -8.07241  1.000 41.03834  ? 172 ASP B C   1 
ATOM   5696 O O   . ASP B 1 173 ? -4.72535  -7.14395  -9.19315  1.000 41.91826  ? 172 ASP B O   1 
ATOM   5697 C CB  . ASP B 1 173 ? -7.71343  -7.55423  -7.78850  1.000 35.70613  ? 172 ASP B CB  1 
ATOM   5698 C CG  . ASP B 1 173 ? -8.77585  -8.60790  -7.66586  1.000 42.07434  ? 172 ASP B CG  1 
ATOM   5699 O OD1 . ASP B 1 173 ? -8.47435  -9.74937  -8.08463  1.000 42.89583  ? 172 ASP B OD1 1 
ATOM   5700 O OD2 . ASP B 1 173 ? -9.89337  -8.32180  -7.15702  1.000 46.04188  ? 172 ASP B OD2 1 
ATOM   5701 N N   . ILE B 1 174 ? -4.86022  -6.27918  -7.11658  1.000 40.37598  ? 173 ILE B N   1 
ATOM   5702 C CA  . ILE B 1 174 ? -3.78915  -5.32949  -7.38338  1.000 38.35965  ? 173 ILE B CA  1 
ATOM   5703 C C   . ILE B 1 174 ? -2.48138  -6.07015  -7.63379  1.000 40.11676  ? 173 ILE B C   1 
ATOM   5704 O O   . ILE B 1 174 ? -1.65164  -5.62898  -8.43494  1.000 44.06280  ? 173 ILE B O   1 
ATOM   5705 C CB  . ILE B 1 174 ? -3.65294  -4.31873  -6.23362  1.000 33.09101  ? 173 ILE B CB  1 
ATOM   5706 C CG1 . ILE B 1 174 ? -4.82615  -3.32380  -6.22275  1.000 31.56764  ? 173 ILE B CG1 1 
ATOM   5707 C CG2 . ILE B 1 174 ? -2.35182  -3.55389  -6.38621  1.000 31.40530  ? 173 ILE B CG2 1 
ATOM   5708 C CD1 . ILE B 1 174 ? -4.56283  -2.01310  -6.94297  1.000 33.38106  ? 173 ILE B CD1 1 
ATOM   5709 N N   . GLU B 1 175 ? -2.28760  -7.22530  -7.00919  1.000 38.69758  ? 174 GLU B N   1 
ATOM   5710 C CA  . GLU B 1 175 ? -1.02657  -7.93012  -7.20366  1.000 38.52930  ? 174 GLU B CA  1 
ATOM   5711 C C   . GLU B 1 175 ? -0.94416  -8.62914  -8.55655  1.000 41.31917  ? 174 GLU B C   1 
ATOM   5712 O O   . GLU B 1 175 ? 0.13427   -8.68652  -9.15326  1.000 42.57343  ? 174 GLU B O   1 
ATOM   5713 C CB  . GLU B 1 175 ? -0.81613  -8.94715  -6.09643  1.000 42.34144  ? 174 GLU B CB  1 
ATOM   5714 C CG  . GLU B 1 175 ? 0.51938   -9.63220  -6.20726  1.000 51.49215  ? 174 GLU B CG  1 
ATOM   5715 C CD  . GLU B 1 175 ? 1.65832   -8.73583  -5.74695  1.000 63.79021  ? 174 GLU B CD  1 
ATOM   5716 O OE1 . GLU B 1 175 ? 1.37856   -7.77244  -4.97373  1.000 58.59509  ? 174 GLU B OE1 1 
ATOM   5717 O OE2 . GLU B 1 175 ? 2.81879   -8.99712  -6.16775  1.000 56.96849  ? 174 GLU B OE2 1 
ATOM   5718 N N   . ARG B 1 176 ? -2.05425  -9.18956  -9.04501  1.000 41.22852  ? 175 ARG B N   1 
ATOM   5719 C CA  . ARG B 1 176 ? -2.04915  -9.97213  -10.27811 1.000 38.36310  ? 175 ARG B CA  1 
ATOM   5720 C C   . ARG B 1 176 ? -2.20255  -9.10363  -11.51493 1.000 39.23060  ? 175 ARG B C   1 
ATOM   5721 O O   . ARG B 1 176 ? -1.64355  -9.42293  -12.57456 1.000 36.60525  ? 175 ARG B O   1 
ATOM   5722 C CB  . ARG B 1 176 ? -3.18055  -11.01909 -10.26497 1.000 38.65407  ? 175 ARG B CB  1 
ATOM   5723 C CG  . ARG B 1 176 ? -3.38341  -11.74230 -8.92333  1.000 41.27805  ? 175 ARG B CG  1 
ATOM   5724 C CD  . ARG B 1 176 ? -4.42826  -12.88070 -8.95218  1.000 36.99972  ? 175 ARG B CD  1 
ATOM   5725 N NE  . ARG B 1 176 ? -3.82025  -14.17854 -8.66048  1.000 45.71654  ? 175 ARG B NE  1 
ATOM   5726 C CZ  . ARG B 1 176 ? -3.45284  -14.59867 -7.44953  1.000 65.70752  ? 175 ARG B CZ  1 
ATOM   5727 N NH1 . ARG B 1 176 ? -3.66721  -13.86752 -6.35933  1.000 63.17942  ? 175 ARG B NH1 1 
ATOM   5728 N NH2 . ARG B 1 176 ? -2.85223  -15.78403 -7.32557  1.000 59.66720  ? 175 ARG B NH2 1 
ATOM   5729 N N   . TYR B 1 177 ? -2.91454  -7.99034  -11.38259 1.000 38.41829  ? 176 TYR B N   1 
ATOM   5730 C CA  . TYR B 1 177 ? -3.50426  -7.31177  -12.51620 1.000 32.90732  ? 176 TYR B CA  1 
ATOM   5731 C C   . TYR B 1 177 ? -3.09702  -5.86244  -12.69544 1.000 34.18456  ? 176 TYR B C   1 
ATOM   5732 O O   . TYR B 1 177 ? -3.33899  -5.31655  -13.77258 1.000 41.15202  ? 176 TYR B O   1 
ATOM   5733 C CB  . TYR B 1 177 ? -5.02504  -7.38042  -12.39770 1.000 32.01489  ? 176 TYR B CB  1 
ATOM   5734 C CG  . TYR B 1 177 ? -5.49626  -8.79983  -12.31365 1.000 35.27796  ? 176 TYR B CG  1 
ATOM   5735 C CD1 . TYR B 1 177 ? -5.05882  -9.73036  -13.22904 1.000 34.39855  ? 176 TYR B CD1 1 
ATOM   5736 C CD2 . TYR B 1 177 ? -6.37491  -9.21535  -11.32289 1.000 39.04447  ? 176 TYR B CD2 1 
ATOM   5737 C CE1 . TYR B 1 177 ? -5.48213  -11.02836 -13.17539 1.000 37.21685  ? 176 TYR B CE1 1 
ATOM   5738 C CE2 . TYR B 1 177 ? -6.81483  -10.51848 -11.26365 1.000 35.36573  ? 176 TYR B CE2 1 
ATOM   5739 C CZ  . TYR B 1 177 ? -6.36175  -11.42585 -12.19616 1.000 38.00344  ? 176 TYR B CZ  1 
ATOM   5740 O OH  . TYR B 1 177 ? -6.77642  -12.74328 -12.17650 1.000 38.48638  ? 176 TYR B OH  1 
ATOM   5741 N N   . ALA B 1 178 ? -2.52280  -5.22270  -11.69146 1.000 36.46618  ? 177 ALA B N   1 
ATOM   5742 C CA  . ALA B 1 178 ? -2.10652  -3.83624  -11.80619 1.000 36.32835  ? 177 ALA B CA  1 
ATOM   5743 C C   . ALA B 1 178 ? -0.75190  -3.76113  -12.50549 1.000 38.99181  ? 177 ALA B C   1 
ATOM   5744 O O   . ALA B 1 178 ? 0.05052   -4.69605  -12.40487 1.000 36.98368  ? 177 ALA B O   1 
ATOM   5745 C CB  . ALA B 1 178 ? -2.02360  -3.18669  -10.42472 1.000 35.77429  ? 177 ALA B CB  1 
ATOM   5746 N N   . PRO B 1 179 ? -0.48058  -2.66331  -13.22929 1.000 35.64351  ? 178 PRO B N   1 
ATOM   5747 C CA  . PRO B 1 179 ? 0.76916   -2.60265  -14.00140 1.000 33.65882  ? 178 PRO B CA  1 
ATOM   5748 C C   . PRO B 1 179 ? 1.99799   -2.49754  -13.12240 1.000 39.30010  ? 178 PRO B C   1 
ATOM   5749 O O   . PRO B 1 179 ? 3.01150   -3.15620  -13.39179 1.000 41.47167  ? 178 PRO B O   1 
ATOM   5750 C CB  . PRO B 1 179 ? 0.59160   -1.35429  -14.87696 1.000 32.39511  ? 178 PRO B CB  1 
ATOM   5751 C CG  . PRO B 1 179 ? -0.73504  -0.78114  -14.54839 1.000 31.65118  ? 178 PRO B CG  1 
ATOM   5752 C CD  . PRO B 1 179 ? -1.23461  -1.40430  -13.30295 1.000 34.96461  ? 178 PRO B CD  1 
ATOM   5753 N N   . GLU B 1 180 ? 1.93758   -1.68916  -12.06444 1.000 42.76170  ? 179 GLU B N   1 
ATOM   5754 C CA  . GLU B 1 180 ? 3.08123   -1.53465  -11.16838 1.000 44.19717  ? 179 GLU B CA  1 
ATOM   5755 C C   . GLU B 1 180 ? 3.51390   -2.85684  -10.53389 1.000 42.89636  ? 179 GLU B C   1 
ATOM   5756 O O   . GLU B 1 180 ? 4.67498   -2.98663  -10.12044 1.000 44.28197  ? 179 GLU B O   1 
ATOM   5757 C CB  . GLU B 1 180 ? 2.73709   -0.50901  -10.09459 1.000 37.27045  ? 179 GLU B CB  1 
ATOM   5758 C CG  . GLU B 1 180 ? 1.76581   -1.04703  -9.07607  1.000 43.77727  ? 179 GLU B CG  1 
ATOM   5759 C CD  . GLU B 1 180 ? 0.34578   -0.52657  -9.23182  1.000 44.15676  ? 179 GLU B CD  1 
ATOM   5760 O OE1 . GLU B 1 180 ? -0.02655  -0.06789  -10.33814 1.000 36.46762  ? 179 GLU B OE1 1 
ATOM   5761 O OE2 . GLU B 1 180 ? -0.39846  -0.59250  -8.22126  1.000 46.76185  ? 179 GLU B OE2 1 
ATOM   5762 N N   . SER B 1 181 ? 2.60821   -3.83827  -10.45777 1.000 40.36932  ? 180 SER B N   1 
ATOM   5763 C CA  . SER B 1 181 ? 2.97786   -5.17378  -10.00428 1.000 40.44520  ? 180 SER B CA  1 
ATOM   5764 C C   . SER B 1 181 ? 3.90029   -5.86997  -10.98426 1.000 40.17410  ? 180 SER B C   1 
ATOM   5765 O O   . SER B 1 181 ? 4.62772   -6.78288  -10.59607 1.000 41.94116  ? 180 SER B O   1 
ATOM   5766 C CB  . SER B 1 181 ? 1.73443   -6.03082  -9.81916  1.000 41.29981  ? 180 SER B CB  1 
ATOM   5767 O OG  . SER B 1 181 ? 0.79615   -5.38310  -8.98987  1.000 50.39797  ? 180 SER B OG  1 
ATOM   5768 N N   . GLY B 1 182 ? 3.85815   -5.48668  -12.25564 1.000 41.29814  ? 181 GLY B N   1 
ATOM   5769 C CA  . GLY B 1 182 ? 4.64174   -6.17380  -13.27430 1.000 39.41689  ? 181 GLY B CA  1 
ATOM   5770 C C   . GLY B 1 182 ? 4.42638   -7.67106  -13.34240 1.000 43.56432  ? 181 GLY B C   1 
ATOM   5771 O O   . GLY B 1 182 ? 5.40047   -8.43387  -13.39997 1.000 53.28851  ? 181 GLY B O   1 
ATOM   5772 N N   . GLY B 1 183 ? 3.16904   -8.11556  -13.32319 1.000 40.23851  ? 182 GLY B N   1 
ATOM   5773 C CA  . GLY B 1 183 ? 2.84597   -9.51158  -13.49539 1.000 33.27778  ? 182 GLY B CA  1 
ATOM   5774 C C   . GLY B 1 183 ? 2.43966   -9.80283  -14.93108 1.000 44.54146  ? 182 GLY B C   1 
ATOM   5775 O O   . GLY B 1 183 ? 2.43565   -8.93108  -15.80289 1.000 46.74887  ? 182 GLY B O   1 
ATOM   5776 N N   . ARG B 1 184 ? 2.07995   -11.06540 -15.16484 1.000 41.81949  ? 183 ARG B N   1 
ATOM   5777 C CA  . ARG B 1 184 ? 1.65158   -11.48533 -16.49044 1.000 35.83858  ? 183 ARG B CA  1 
ATOM   5778 C C   . ARG B 1 184 ? 0.68527   -12.65666 -16.38336 1.000 36.36012  ? 183 ARG B C   1 
ATOM   5779 O O   . ARG B 1 184 ? 0.99451   -13.66080 -15.73572 1.000 43.89209  ? 183 ARG B O   1 
ATOM   5780 C CB  . ARG B 1 184 ? 2.87349   -11.83009 -17.35486 1.000 39.70299  ? 183 ARG B CB  1 
ATOM   5781 C CG  . ARG B 1 184 ? 3.47421   -13.19307 -17.15138 1.000 33.43613  ? 183 ARG B CG  1 
ATOM   5782 C CD  . ARG B 1 184 ? 4.62831   -13.09453 -16.22462 1.000 33.29710  ? 183 ARG B CD  1 
ATOM   5783 N NE  . ARG B 1 184 ? 5.33610   -14.35418 -16.02977 1.000 43.12810  ? 183 ARG B NE  1 
ATOM   5784 C CZ  . ARG B 1 184 ? 4.87328   -15.38852 -15.33168 1.000 49.12399  ? 183 ARG B CZ  1 
ATOM   5785 N NH1 . ARG B 1 184 ? 3.61029   -15.44808 -14.92713 1.000 43.13309  ? 183 ARG B NH1 1 
ATOM   5786 N NH2 . ARG B 1 184 ? 5.69619   -16.39717 -15.03890 1.000 50.18399  ? 183 ARG B NH2 1 
ATOM   5787 N N   . PHE B 1 185 ? -0.48645  -12.52896 -17.00626 1.000 33.31755  ? 184 PHE B N   1 
ATOM   5788 C CA  . PHE B 1 185 ? -1.49162  -13.58700 -16.97935 1.000 34.96083  ? 184 PHE B CA  1 
ATOM   5789 C C   . PHE B 1 185 ? -1.95076  -13.97991 -18.38570 1.000 41.13169  ? 184 PHE B C   1 
ATOM   5790 O O   . PHE B 1 185 ? -1.78799  -13.23611 -19.35604 1.000 40.90146  ? 184 PHE B O   1 
ATOM   5791 C CB  . PHE B 1 185 ? -2.70060  -13.16222 -16.18051 1.000 30.78762  ? 184 PHE B CB  1 
ATOM   5792 C CG  . PHE B 1 185 ? -3.08652  -11.74582 -16.40397 1.000 33.64848  ? 184 PHE B CG  1 
ATOM   5793 C CD1 . PHE B 1 185 ? -2.45087  -10.72099 -15.70359 1.000 28.76096  ? 184 PHE B CD1 1 
ATOM   5794 C CD2 . PHE B 1 185 ? -4.09120  -11.42957 -17.32049 1.000 36.02565  ? 184 PHE B CD2 1 
ATOM   5795 C CE1 . PHE B 1 185 ? -2.80946  -9.39790  -15.90989 1.000 34.08382  ? 184 PHE B CE1 1 
ATOM   5796 C CE2 . PHE B 1 185 ? -4.45901  -10.10592 -17.54037 1.000 37.52903  ? 184 PHE B CE2 1 
ATOM   5797 C CZ  . PHE B 1 185 ? -3.82008  -9.08245  -16.82949 1.000 36.72488  ? 184 PHE B CZ  1 
ATOM   5798 N N   . ALA B 1 186 ? -2.52853  -15.17512 -18.48179 1.000 39.59511  ? 185 ALA B N   1 
ATOM   5799 C CA  . ALA B 1 186 ? -3.30962  -15.54072 -19.64651 1.000 35.22649  ? 185 ALA B CA  1 
ATOM   5800 C C   . ALA B 1 186 ? -4.67532  -14.87197 -19.58190 1.000 32.15207  ? 185 ALA B C   1 
ATOM   5801 O O   . ALA B 1 186 ? -5.14560  -14.47216 -18.52207 1.000 38.19987  ? 185 ALA B O   1 
ATOM   5802 C CB  . ALA B 1 186 ? -3.48759  -17.05105 -19.73580 1.000 34.96165  ? 185 ALA B CB  1 
ATOM   5803 N N   . LEU B 1 187 ? -5.30272  -14.73714 -20.73805 1.000 38.67930  ? 186 LEU B N   1 
ATOM   5804 C CA  . LEU B 1 187 ? -6.64690  -14.20016 -20.83068 1.000 34.87107  ? 186 LEU B CA  1 
ATOM   5805 C C   . LEU B 1 187 ? -7.60601  -15.36381 -21.00016 1.000 40.64497  ? 186 LEU B C   1 
ATOM   5806 O O   . LEU B 1 187 ? -7.24215  -16.40094 -21.57067 1.000 42.98699  ? 186 LEU B O   1 
ATOM   5807 C CB  . LEU B 1 187 ? -6.78109  -13.23597 -22.01283 1.000 30.87730  ? 186 LEU B CB  1 
ATOM   5808 C CG  . LEU B 1 187 ? -5.98604  -11.93381 -22.00845 1.000 29.29399  ? 186 LEU B CG  1 
ATOM   5809 C CD1 . LEU B 1 187 ? -6.00563  -11.37569 -23.39210 1.000 38.74162  ? 186 LEU B CD1 1 
ATOM   5810 C CD2 . LEU B 1 187 ? -6.57387  -10.91636 -21.06878 1.000 27.06638  ? 186 LEU B CD2 1 
ATOM   5811 N N   . GLU B 1 188 ? -8.83375  -15.18431 -20.50024 1.000 37.37739  ? 187 GLU B N   1 
ATOM   5812 C CA  . GLU B 1 188 ? -9.88581  -16.18882 -20.63077 1.000 33.87507  ? 187 GLU B CA  1 
ATOM   5813 C C   . GLU B 1 188 ? -10.60608 -16.00628 -21.95397 1.000 37.54436  ? 187 GLU B C   1 
ATOM   5814 O O   . GLU B 1 188 ? -11.08144 -14.90782 -22.25315 1.000 41.79206  ? 187 GLU B O   1 
ATOM   5815 C CB  . GLU B 1 188 ? -10.89179 -16.09144 -19.48571 1.000 32.38803  ? 187 GLU B CB  1 
ATOM   5816 C CG  . GLU B 1 188 ? -10.46865 -16.81474 -18.21720 1.000 37.95873  ? 187 GLU B CG  1 
ATOM   5817 C CD  . GLU B 1 188 ? -9.99620  -18.25898 -18.45609 1.000 49.67983  ? 187 GLU B CD  1 
ATOM   5818 O OE1 . GLU B 1 188 ? -10.41782 -18.90693 -19.44628 1.000 56.55843  ? 187 GLU B OE1 1 
ATOM   5819 O OE2 . GLU B 1 188 ? -9.19444  -18.75730 -17.64030 1.000 49.22021  ? 187 GLU B OE2 1 
ATOM   5820 N N   . TRP B 1 189 ? -10.68910 -17.07763 -22.74120 1.000 39.37611  ? 188 TRP B N   1 
ATOM   5821 C CA  . TRP B 1 189 ? -11.37034 -17.04697 -24.03074 1.000 38.15752  ? 188 TRP B CA  1 
ATOM   5822 C C   . TRP B 1 189 ? -12.71485 -17.74748 -23.93589 1.000 38.13541  ? 188 TRP B C   1 
ATOM   5823 O O   . TRP B 1 189 ? -12.85578 -18.74856 -23.22713 1.000 43.11108  ? 188 TRP B O   1 
ATOM   5824 C CB  . TRP B 1 189 ? -10.53398 -17.71213 -25.11396 1.000 37.00197  ? 188 TRP B CB  1 
ATOM   5825 C CG  . TRP B 1 189 ? -9.39284  -16.88478 -25.60756 1.000 39.38884  ? 188 TRP B CG  1 
ATOM   5826 C CD1 . TRP B 1 189 ? -8.15364  -16.79225 -25.05622 1.000 36.96939  ? 188 TRP B CD1 1 
ATOM   5827 C CD2 . TRP B 1 189 ? -9.37983  -16.04350 -26.76821 1.000 40.01460  ? 188 TRP B CD2 1 
ATOM   5828 N NE1 . TRP B 1 189 ? -7.36530  -15.95150 -25.80499 1.000 35.99985  ? 188 TRP B NE1 1 
ATOM   5829 C CE2 . TRP B 1 189 ? -8.09632  -15.47537 -26.85784 1.000 37.56383  ? 188 TRP B CE2 1 
ATOM   5830 C CE3 . TRP B 1 189 ? -10.32585 -15.71792 -27.73646 1.000 36.44830  ? 188 TRP B CE3 1 
ATOM   5831 C CZ2 . TRP B 1 189 ? -7.73731  -14.60595 -27.87457 1.000 34.89324  ? 188 TRP B CZ2 1 
ATOM   5832 C CZ3 . TRP B 1 189 ? -9.96664  -14.85267 -28.73981 1.000 37.41899  ? 188 TRP B CZ3 1 
ATOM   5833 C CH2 . TRP B 1 189 ? -8.68503  -14.30616 -28.80145 1.000 37.90270  ? 188 TRP B CH2 1 
ATOM   5834 N N   . VAL B 1 190 ? -13.71089 -17.20282 -24.63317 1.000 38.52944  ? 189 VAL B N   1 
ATOM   5835 C CA  . VAL B 1 190 ? -15.06229 -17.75566 -24.62825 1.000 41.76107  ? 189 VAL B CA  1 
ATOM   5836 C C   . VAL B 1 190 ? -15.64402 -17.64425 -26.03183 1.000 35.89757  ? 189 VAL B C   1 
ATOM   5837 O O   . VAL B 1 190 ? -15.32834 -16.71948 -26.78279 1.000 39.89601  ? 189 VAL B O   1 
ATOM   5838 C CB  . VAL B 1 190 ? -15.99438 -17.04047 -23.61518 1.000 38.53461  ? 189 VAL B CB  1 
ATOM   5839 C CG1 . VAL B 1 190 ? -15.23843 -16.60818 -22.37064 1.000 38.97778  ? 189 VAL B CG1 1 
ATOM   5840 C CG2 . VAL B 1 190 ? -16.65681 -15.85085 -24.25364 1.000 36.61452  ? 189 VAL B CG2 1 
ATOM   5841 N N   . ALA B 1 191 ? -16.49826 -18.59030 -26.39073 1.000 32.72337  ? 190 ALA B N   1 
ATOM   5842 C CA  . ALA B 1 191 ? -17.24884 -18.47939 -27.62828 1.000 36.41079  ? 190 ALA B CA  1 
ATOM   5843 C C   . ALA B 1 191 ? -18.59130 -17.82139 -27.35035 1.000 38.40901  ? 190 ALA B C   1 
ATOM   5844 O O   . ALA B 1 191 ? -19.23244 -18.11551 -26.34183 1.000 41.70980  ? 190 ALA B O   1 
ATOM   5845 C CB  . ALA B 1 191 ? -17.45303 -19.84939 -28.26311 1.000 39.25996  ? 190 ALA B CB  1 
ATOM   5846 N N   . VAL B 1 192 ? -19.01983 -16.93706 -28.25234 1.000 37.83646  ? 191 VAL B N   1 
ATOM   5847 C CA  . VAL B 1 192 ? -20.26006 -16.18304 -28.09454 1.000 34.41047  ? 191 VAL B CA  1 
ATOM   5848 C C   . VAL B 1 192 ? -21.09998 -16.27929 -29.36246 1.000 42.21726  ? 191 VAL B C   1 
ATOM   5849 O O   . VAL B 1 192 ? -20.57747 -16.22993 -30.48495 1.000 43.98276  ? 191 VAL B O   1 
ATOM   5850 C CB  . VAL B 1 192 ? -19.97973 -14.71154 -27.75634 1.000 38.57688  ? 191 VAL B CB  1 
ATOM   5851 C CG1 . VAL B 1 192 ? -19.38085 -14.62053 -26.35987 1.000 40.93034  ? 191 VAL B CG1 1 
ATOM   5852 C CG2 . VAL B 1 192 ? -19.05927 -14.07766 -28.80037 1.000 35.93544  ? 191 VAL B CG2 1 
ATOM   5853 N N   . LEU B 1 193 ? -22.40742 -16.41204 -29.18109 1.000 40.73153  ? 192 LEU B N   1 
ATOM   5854 C CA  . LEU B 1 193 ? -23.31949 -16.51893 -30.31228 1.000 44.51961  ? 192 LEU B CA  1 
ATOM   5855 C C   . LEU B 1 193 ? -23.16108 -15.34499 -31.27609 1.000 46.50773  ? 192 LEU B C   1 
ATOM   5856 O O   . LEU B 1 193 ? -23.35918 -14.18631 -30.89431 1.000 47.04941  ? 192 LEU B O   1 
ATOM   5857 C CB  . LEU B 1 193 ? -24.75432 -16.58306 -29.79321 1.000 45.82545  ? 192 LEU B CB  1 
ATOM   5858 C CG  . LEU B 1 193 ? -25.32281 -17.99166 -29.67909 1.000 46.86615  ? 192 LEU B CG  1 
ATOM   5859 C CD1 . LEU B 1 193 ? -26.83841 -17.93617 -29.74755 1.000 41.30890  ? 192 LEU B CD1 1 
ATOM   5860 C CD2 . LEU B 1 193 ? -24.73868 -18.89917 -30.76715 1.000 42.07257  ? 192 LEU B CD2 1 
ATOM   5861 N N   . ARG B 1 194 ? -22.83208 -15.65136 -32.53859 1.000 43.64659  ? 193 ARG B N   1 
ATOM   5862 C CA  . ARG B 1 194 ? -22.66919 -14.59951 -33.54363 1.000 41.82449  ? 193 ARG B CA  1 
ATOM   5863 C C   . ARG B 1 194 ? -23.91654 -13.74042 -33.68586 1.000 39.07375  ? 193 ARG B C   1 
ATOM   5864 O O   . ARG B 1 194 ? -23.81992 -12.56369 -34.05266 1.000 42.55935  ? 193 ARG B O   1 
ATOM   5865 C CB  . ARG B 1 194 ? -22.29725 -15.20503 -34.89946 1.000 35.93103  ? 193 ARG B CB  1 
ATOM   5866 C CG  . ARG B 1 194 ? -20.89835 -15.75367 -34.94687 1.000 39.23914  ? 193 ARG B CG  1 
ATOM   5867 C CD  . ARG B 1 194 ? -20.47615 -16.16511 -36.31964 1.000 37.77796  ? 193 ARG B CD  1 
ATOM   5868 N NE  . ARG B 1 194 ? -19.17799 -16.83034 -36.28359 1.000 42.25989  ? 193 ARG B NE  1 
ATOM   5869 C CZ  . ARG B 1 194 ? -18.35373 -16.92123 -37.31865 1.000 43.99268  ? 193 ARG B CZ  1 
ATOM   5870 N NH1 . ARG B 1 194 ? -18.66094 -16.39155 -38.49412 1.000 45.05330  ? 193 ARG B NH1 1 
ATOM   5871 N NH2 . ARG B 1 194 ? -17.19260 -17.55709 -37.17113 1.000 42.23902  ? 193 ARG B NH2 1 
ATOM   5872 N N   . VAL B 1 195 ? -25.09236 -14.30137 -33.41207 1.000 39.94215  ? 194 VAL B N   1 
ATOM   5873 C CA  . VAL B 1 195 ? -26.31248 -13.50792 -33.51298 1.000 43.95275  ? 194 VAL B CA  1 
ATOM   5874 C C   . VAL B 1 195 ? -26.46485 -12.55461 -32.34071 1.000 46.34868  ? 194 VAL B C   1 
ATOM   5875 O O   . VAL B 1 195 ? -27.22394 -11.58348 -32.43284 1.000 51.82806  ? 194 VAL B O   1 
ATOM   5876 C CB  . VAL B 1 195 ? -27.55349 -14.40918 -33.63575 1.000 38.72755  ? 194 VAL B CB  1 
ATOM   5877 C CG1 . VAL B 1 195 ? -27.37441 -15.35111 -34.79662 1.000 43.98979  ? 194 VAL B CG1 1 
ATOM   5878 C CG2 . VAL B 1 195 ? -27.76111 -15.20582 -32.37617 1.000 40.25099  ? 194 VAL B CG2 1 
ATOM   5879 N N   . ASN B 1 196 ? -25.77300 -12.79874 -31.23704 1.000 46.60502  ? 195 ASN B N   1 
ATOM   5880 C CA  . ASN B 1 196 ? -25.75939 -11.84619 -30.14370 1.000 47.02202  ? 195 ASN B CA  1 
ATOM   5881 C C   . ASN B 1 196 ? -24.51102 -10.98338 -30.14295 1.000 46.45998  ? 195 ASN B C   1 
ATOM   5882 O O   . ASN B 1 196 ? -24.33273 -10.18643 -29.22076 1.000 51.65569  ? 195 ASN B O   1 
ATOM   5883 C CB  . ASN B 1 196 ? -25.87909 -12.56683 -28.79962 1.000 46.57006  ? 195 ASN B CB  1 
ATOM   5884 C CG  . ASN B 1 196 ? -27.19764 -13.27465 -28.63470 1.000 48.10071  ? 195 ASN B CG  1 
ATOM   5885 O OD1 . ASN B 1 196 ? -28.22639 -12.82405 -29.12557 1.000 55.53997  ? 195 ASN B OD1 1 
ATOM   5886 N ND2 . ASN B 1 196 ? -27.17416 -14.39430 -27.93794 1.000 51.41444  ? 195 ASN B ND2 1 
ATOM   5887 N N   . THR B 1 197 ? -23.64333 -11.11588 -31.13960 1.000 41.50571  ? 196 THR B N   1 
ATOM   5888 C CA  . THR B 1 197 ? -22.35810 -10.43799 -31.12798 1.000 40.35896  ? 196 THR B CA  1 
ATOM   5889 C C   . THR B 1 197 ? -22.21392 -9.57028  -32.36470 1.000 41.53925  ? 196 THR B C   1 
ATOM   5890 O O   . THR B 1 197 ? -22.48676 -10.02158 -33.47908 1.000 47.67046  ? 196 THR B O   1 
ATOM   5891 C CB  . THR B 1 197 ? -21.19990 -11.43796 -31.05956 1.000 42.07927  ? 196 THR B CB  1 
ATOM   5892 O OG1 . THR B 1 197 ? -21.49080 -12.43799 -30.07893 1.000 45.82379  ? 196 THR B OG1 1 
ATOM   5893 C CG2 . THR B 1 197 ? -19.91631 -10.73725 -30.65453 1.000 36.38672  ? 196 THR B CG2 1 
ATOM   5894 N N   . ASP B 1 198 ? -21.81073 -8.32324  -32.15417 1.000 38.67704  ? 197 ASP B N   1 
ATOM   5895 C CA  . ASP B 1 198 ? -21.21276 -7.50637  -33.19219 1.000 35.07079  ? 197 ASP B CA  1 
ATOM   5896 C C   . ASP B 1 198 ? -19.71189 -7.75446  -33.21377 1.000 39.18676  ? 197 ASP B C   1 
ATOM   5897 O O   . ASP B 1 198 ? -19.05477 -7.72613  -32.16769 1.000 41.23806  ? 197 ASP B O   1 
ATOM   5898 C CB  . ASP B 1 198 ? -21.46836 -6.02497  -32.94041 1.000 44.92789  ? 197 ASP B CB  1 
ATOM   5899 C CG  . ASP B 1 198 ? -22.93452 -5.69085  -32.84377 1.000 56.55113  ? 197 ASP B CG  1 
ATOM   5900 O OD1 . ASP B 1 198 ? -23.70140 -6.08544  -33.75396 1.000 53.40701  ? 197 ASP B OD1 1 
ATOM   5901 O OD2 . ASP B 1 198 ? -23.30829 -5.00734  -31.86111 1.000 61.28255  ? 197 ASP B OD2 1 
ATOM   5902 N N   . PHE B 1 199 ? -19.17250 -8.00626  -34.39597 1.000 38.14569  ? 198 PHE B N   1 
ATOM   5903 C CA  . PHE B 1 199 ? -17.73933 -7.93752  -34.62298 1.000 36.63977  ? 198 PHE B CA  1 
ATOM   5904 C C   . PHE B 1 199 ? -17.50124 -6.94623  -35.75535 1.000 37.03022  ? 198 PHE B C   1 
ATOM   5905 O O   . PHE B 1 199 ? -18.36468 -6.73416  -36.60403 1.000 34.25039  ? 198 PHE B O   1 
ATOM   5906 C CB  . PHE B 1 199 ? -17.15453 -9.32064  -34.93577 1.000 33.35020  ? 198 PHE B CB  1 
ATOM   5907 C CG  . PHE B 1 199 ? -15.72440 -9.29684  -35.42118 1.000 40.92162  ? 198 PHE B CG  1 
ATOM   5908 C CD1 . PHE B 1 199 ? -15.42089 -9.03859  -36.76496 1.000 33.14290  ? 198 PHE B CD1 1 
ATOM   5909 C CD2 . PHE B 1 199 ? -14.67588 -9.56945  -34.54299 1.000 41.74956  ? 198 PHE B CD2 1 
ATOM   5910 C CE1 . PHE B 1 199 ? -14.10287 -9.02680  -37.21003 1.000 33.22503  ? 198 PHE B CE1 1 
ATOM   5911 C CE2 . PHE B 1 199 ? -13.34043 -9.56811  -34.99049 1.000 40.65571  ? 198 PHE B CE2 1 
ATOM   5912 C CZ  . PHE B 1 199 ? -13.05808 -9.29635  -36.32151 1.000 41.23748  ? 198 PHE B CZ  1 
ATOM   5913 N N   . ALA B 1 200 ? -16.33820 -6.31105  -35.74517 1.000 38.27826  ? 199 ALA B N   1 
ATOM   5914 C CA  . ALA B 1 200 ? -16.09615 -5.18899  -36.63435 1.000 37.61671  ? 199 ALA B CA  1 
ATOM   5915 C C   . ALA B 1 200 ? -14.59978 -5.04396  -36.81347 1.000 39.66701  ? 199 ALA B C   1 
ATOM   5916 O O   . ALA B 1 200 ? -13.83975 -5.17988  -35.85451 1.000 45.13509  ? 199 ALA B O   1 
ATOM   5917 C CB  . ALA B 1 200 ? -16.69853 -3.89474  -36.07810 1.000 43.75614  ? 199 ALA B CB  1 
ATOM   5918 N N   . ALA B 1 201 ? -14.17923 -4.77598  -38.03884 1.000 39.30841  ? 200 ALA B N   1 
ATOM   5919 C CA  . ALA B 1 201 ? -12.75879 -4.80828  -38.31331 1.000 41.77688  ? 200 ALA B CA  1 
ATOM   5920 C C   . ALA B 1 201 ? -12.41002 -3.77106  -39.36564 1.000 48.69390  ? 200 ALA B C   1 
ATOM   5921 O O   . ALA B 1 201 ? -13.27406 -3.21440  -40.04803 1.000 50.93543  ? 200 ALA B O   1 
ATOM   5922 C CB  . ALA B 1 201 ? -12.30859 -6.20186  -38.75486 1.000 37.03080  ? 200 ALA B CB  1 
ATOM   5923 N N   . MET B 1 202 ? -11.11952 -3.50374  -39.46135 1.000 49.27449  ? 201 MET B N   1 
ATOM   5924 C CA  . MET B 1 202 ? -10.61186 -2.56068  -40.42567 1.000 47.79888  ? 201 MET B CA  1 
ATOM   5925 C C   . MET B 1 202 ? -10.43372 -3.25394  -41.76564 1.000 51.12240  ? 201 MET B C   1 
ATOM   5926 O O   . MET B 1 202 ? -10.31889 -4.48133  -41.84246 1.000 49.72585  ? 201 MET B O   1 
ATOM   5927 C CB  . MET B 1 202 ? -9.28065  -1.99048  -39.95217 1.000 51.85916  ? 201 MET B CB  1 
ATOM   5928 C CG  . MET B 1 202 ? -9.39876  -0.76033  -39.10309 1.000 47.18513  ? 201 MET B CG  1 
ATOM   5929 S SD  . MET B 1 202 ? -7.74276  -0.42165  -38.54876 1.000 49.59442  ? 201 MET B SD  1 
ATOM   5930 C CE  . MET B 1 202 ? -7.46405  1.18871   -39.27278 1.000 52.49988  ? 201 MET B CE  1 
ATOM   5931 N N   . SER B 1 203 ? -10.42321 -2.45002  -42.82832 1.000 50.48378  ? 202 SER B N   1 
ATOM   5932 C CA  . SER B 1 203 ? -10.08918 -2.96095  -44.14473 1.000 48.01339  ? 202 SER B CA  1 
ATOM   5933 C C   . SER B 1 203 ? -8.68944  -3.54090  -44.11825 1.000 47.96364  ? 202 SER B C   1 
ATOM   5934 O O   . SER B 1 203 ? -7.71848  -2.82460  -43.85910 1.000 53.18061  ? 202 SER B O   1 
ATOM   5935 C CB  . SER B 1 203 ? -10.18633 -1.84406  -45.17575 1.000 57.63006  ? 202 SER B CB  1 
ATOM   5936 O OG  . SER B 1 203 ? -11.51228 -1.38056  -45.27553 1.000 58.97215  ? 202 SER B OG  1 
ATOM   5937 N N   . GLY B 1 204 ? -8.58506  -4.83993  -44.37045 1.000 46.41999  ? 203 GLY B N   1 
ATOM   5938 C CA  . GLY B 1 204 ? -7.31354  -5.53496  -44.31268 1.000 50.50252  ? 203 GLY B CA  1 
ATOM   5939 C C   . GLY B 1 204 ? -7.23079  -6.56513  -43.21781 1.000 48.41779  ? 203 GLY B C   1 
ATOM   5940 O O   . GLY B 1 204 ? -6.30046  -7.37996  -43.22274 1.000 50.14333  ? 203 GLY B O   1 
ATOM   5941 N N   . THR B 1 205 ? -8.18243  -6.55089  -42.28821 1.000 47.77906  ? 204 THR B N   1 
ATOM   5942 C CA  . THR B 1 205 ? -8.25442  -7.45858  -41.15654 1.000 46.22771  ? 204 THR B CA  1 
ATOM   5943 C C   . THR B 1 205 ? -9.58231  -8.19773  -41.22475 1.000 45.16477  ? 204 THR B C   1 
ATOM   5944 O O   . THR B 1 205 ? -10.62403 -7.59421  -41.50480 1.000 41.00760  ? 204 THR B O   1 
ATOM   5945 C CB  . THR B 1 205 ? -8.12592  -6.67633  -39.83090 1.000 50.96650  ? 204 THR B CB  1 
ATOM   5946 O OG1 . THR B 1 205 ? -6.81839  -6.08824  -39.73915 1.000 46.82642  ? 204 THR B OG1 1 
ATOM   5947 C CG2 . THR B 1 205 ? -8.40720  -7.56225  -38.60016 1.000 44.57696  ? 204 THR B CG2 1 
ATOM   5948 N N   . GLU B 1 206 ? -9.54130  -9.50709  -40.99346 1.000 46.09827  ? 205 GLU B N   1 
ATOM   5949 C CA  . GLU B 1 206 ? -10.72749 -10.34997 -41.06124 1.000 48.75356  ? 205 GLU B CA  1 
ATOM   5950 C C   . GLU B 1 206 ? -10.76008 -11.25260 -39.82970 1.000 47.39532  ? 205 GLU B C   1 
ATOM   5951 O O   . GLU B 1 206 ? -9.71169  -11.63394 -39.30348 1.000 49.40447  ? 205 GLU B O   1 
ATOM   5952 C CB  . GLU B 1 206 ? -10.74601 -11.18489 -42.38092 1.000 43.06767  ? 205 GLU B CB  1 
ATOM   5953 N N   . TYR B 1 207 ? -11.96909 -11.58103 -39.35694 1.000 43.00448  ? 206 TYR B N   1 
ATOM   5954 C CA  . TYR B 1 207 ? -12.08355 -12.41538 -38.16282 1.000 38.29712  ? 206 TYR B CA  1 
ATOM   5955 C C   . TYR B 1 207 ? -11.31086 -13.71351 -38.32499 1.000 44.18514  ? 206 TYR B C   1 
ATOM   5956 O O   . TYR B 1 207 ? -10.51412 -14.07929 -37.45728 1.000 50.31568  ? 206 TYR B O   1 
ATOM   5957 C CB  . TYR B 1 207 ? -13.54672 -12.72040 -37.81985 1.000 38.65117  ? 206 TYR B CB  1 
ATOM   5958 C CG  . TYR B 1 207 ? -13.68436 -13.80726 -36.76592 1.000 42.99386  ? 206 TYR B CG  1 
ATOM   5959 C CD1 . TYR B 1 207 ? -13.29291 -13.57483 -35.44448 1.000 45.68824  ? 206 TYR B CD1 1 
ATOM   5960 C CD2 . TYR B 1 207 ? -14.18569 -15.06526 -37.08170 1.000 40.49211  ? 206 TYR B CD2 1 
ATOM   5961 C CE1 . TYR B 1 207 ? -13.39239 -14.56508 -34.46236 1.000 41.01750  ? 206 TYR B CE1 1 
ATOM   5962 C CE2 . TYR B 1 207 ? -14.30182 -16.05998 -36.10088 1.000 49.81770  ? 206 TYR B CE2 1 
ATOM   5963 C CZ  . TYR B 1 207 ? -13.89243 -15.80201 -34.78800 1.000 45.47398  ? 206 TYR B CZ  1 
ATOM   5964 O OH  . TYR B 1 207 ? -13.98205 -16.77467 -33.81380 1.000 35.94208  ? 206 TYR B OH  1 
ATOM   5965 N N   . ASP B 1 208 ? -11.51167 -14.42092 -39.43679 1.000 46.33384  ? 207 ASP B N   1 
ATOM   5966 C CA  . ASP B 1 208 ? -10.89063 -15.73970 -39.55946 1.000 47.90740  ? 207 ASP B CA  1 
ATOM   5967 C C   . ASP B 1 208 ? -9.36549  -15.64384 -39.61484 1.000 43.95321  ? 207 ASP B C   1 
ATOM   5968 O O   . ASP B 1 208 ? -8.66067  -16.48228 -39.04077 1.000 47.93437  ? 207 ASP B O   1 
ATOM   5969 C CB  . ASP B 1 208 ? -11.45051 -16.47234 -40.77783 1.000 46.14489  ? 207 ASP B CB  1 
ATOM   5970 C CG  . ASP B 1 208 ? -12.95120 -16.72116 -40.66286 1.000 62.07774  ? 207 ASP B CG  1 
ATOM   5971 O OD1 . ASP B 1 208 ? -13.35812 -17.54418 -39.80925 1.000 64.71322  ? 207 ASP B OD1 1 
ATOM   5972 O OD2 . ASP B 1 208 ? -13.72861 -16.07858 -41.40903 1.000 69.40373  ? 207 ASP B OD2 1 
ATOM   5973 N N   . THR B 1 209 ? -8.83232  -14.62741 -40.27178 1.000 38.42570  ? 208 THR B N   1 
ATOM   5974 C CA  . THR B 1 209 ? -7.38537  -14.51436 -40.31728 1.000 37.20778  ? 208 THR B CA  1 
ATOM   5975 C C   . THR B 1 209 ? -6.81137  -13.95353 -39.02647 1.000 39.84636  ? 208 THR B C   1 
ATOM   5976 O O   . THR B 1 209 ? -5.70191  -14.33275 -38.64111 1.000 38.00422  ? 208 THR B O   1 
ATOM   5977 C CB  . THR B 1 209 ? -6.97217  -13.64798 -41.49952 1.000 38.38130  ? 208 THR B CB  1 
ATOM   5978 O OG1 . THR B 1 209 ? -7.94278  -12.60888 -41.66418 1.000 46.43512  ? 208 THR B OG1 1 
ATOM   5979 C CG2 . THR B 1 209 ? -6.90860  -14.47728 -42.75616 1.000 41.17060  ? 208 THR B CG2 1 
ATOM   5980 N N   . LEU B 1 210 ? -7.53390  -13.05140 -38.35264 1.000 43.60529  ? 209 LEU B N   1 
ATOM   5981 C CA  . LEU B 1 210 ? -7.03203  -12.48698 -37.09999 1.000 42.82626  ? 209 LEU B CA  1 
ATOM   5982 C C   . LEU B 1 210 ? -7.06774  -13.52815 -35.98703 1.000 42.71399  ? 209 LEU B C   1 
ATOM   5983 O O   . LEU B 1 210 ? -6.08789  -13.70154 -35.25413 1.000 43.78289  ? 209 LEU B O   1 
ATOM   5984 C CB  . LEU B 1 210 ? -7.83024  -11.23191 -36.70791 1.000 39.58351  ? 209 LEU B CB  1 
ATOM   5985 C CG  . LEU B 1 210 ? -7.70581  -10.72090 -35.25811 1.000 42.56962  ? 209 LEU B CG  1 
ATOM   5986 C CD1 . LEU B 1 210 ? -6.48666  -9.83067  -35.04627 1.000 42.49032  ? 209 LEU B CD1 1 
ATOM   5987 C CD2 . LEU B 1 210 ? -8.94851  -9.97581  -34.82910 1.000 38.25147  ? 209 LEU B CD2 1 
ATOM   5988 N N   . ILE B 1 211 ? -8.17950  -14.25342 -35.86591 1.000 38.04350  ? 210 ILE B N   1 
ATOM   5989 C CA  . ILE B 1 211 ? -8.29199  -15.24511 -34.80999 1.000 37.87202  ? 210 ILE B CA  1 
ATOM   5990 C C   . ILE B 1 211 ? -7.24380  -16.33348 -34.99521 1.000 38.90167  ? 210 ILE B C   1 
ATOM   5991 O O   . ILE B 1 211 ? -6.77984  -16.93257 -34.01763 1.000 42.99796  ? 210 ILE B O   1 
ATOM   5992 C CB  . ILE B 1 211 ? -9.73884  -15.79402 -34.75851 1.000 44.97461  ? 210 ILE B CB  1 
ATOM   5993 C CG1 . ILE B 1 211 ? -10.13362 -16.17534 -33.33312 1.000 46.34125  ? 210 ILE B CG1 1 
ATOM   5994 C CG2 . ILE B 1 211 ? -9.91919  -16.99280 -35.66473 1.000 43.46379  ? 210 ILE B CG2 1 
ATOM   5995 C CD1 . ILE B 1 211 ? -9.99176  -15.05692 -32.33234 1.000 44.73654  ? 210 ILE B CD1 1 
ATOM   5996 N N   . ARG B 1 212 ? -6.81305  -16.57712 -36.23335 1.000 40.42750  ? 211 ARG B N   1 
ATOM   5997 C CA  . ARG B 1 212 ? -5.76642  -17.57266 -36.44883 1.000 42.83607  ? 211 ARG B CA  1 
ATOM   5998 C C   . ARG B 1 212 ? -4.40011  -17.00348 -36.09882 1.000 43.69806  ? 211 ARG B C   1 
ATOM   5999 O O   . ARG B 1 212 ? -3.57110  -17.69795 -35.50064 1.000 45.27627  ? 211 ARG B O   1 
ATOM   6000 C CB  . ARG B 1 212 ? -5.78805  -18.08762 -37.89437 1.000 33.00959  ? 211 ARG B CB  1 
ATOM   6001 N N   . ASP B 1 213 ? -4.16192  -15.73472 -36.43664 1.000 38.86659  ? 212 ASP B N   1 
ATOM   6002 C CA  . ASP B 1 213 ? -2.87732  -15.11575 -36.13442 1.000 36.98130  ? 212 ASP B CA  1 
ATOM   6003 C C   . ASP B 1 213 ? -2.66275  -14.96553 -34.63032 1.000 47.48300  ? 212 ASP B C   1 
ATOM   6004 O O   . ASP B 1 213 ? -1.53700  -15.11601 -34.13977 1.000 47.43932  ? 212 ASP B O   1 
ATOM   6005 C CB  . ASP B 1 213 ? -2.79031  -13.75481 -36.81381 1.000 43.88040  ? 212 ASP B CB  1 
ATOM   6006 C CG  . ASP B 1 213 ? -2.59551  -13.85246 -38.32475 1.000 52.50730  ? 212 ASP B CG  1 
ATOM   6007 O OD1 . ASP B 1 213 ? -2.22704  -14.94653 -38.83020 1.000 51.11770  ? 212 ASP B OD1 1 
ATOM   6008 O OD2 . ASP B 1 213 ? -2.80086  -12.81214 -39.00167 1.000 51.04673  ? 212 ASP B OD2 1 
ATOM   6009 N N   . GLU B 1 214 ? -3.72808  -14.66189 -33.87952 1.000 47.46732  ? 213 GLU B N   1 
ATOM   6010 C CA  . GLU B 1 214 ? -3.59886  -14.43007 -32.44861 1.000 40.90473  ? 213 GLU B CA  1 
ATOM   6011 C C   . GLU B 1 214 ? -3.59179  -15.71423 -31.62521 1.000 50.42970  ? 213 GLU B C   1 
ATOM   6012 O O   . GLU B 1 214 ? -3.09929  -15.69068 -30.49072 1.000 50.98463  ? 213 GLU B O   1 
ATOM   6013 C CB  . GLU B 1 214 ? -4.72302  -13.52289 -31.96906 1.000 38.10666  ? 213 GLU B CB  1 
ATOM   6014 C CG  . GLU B 1 214 ? -4.55288  -12.08117 -32.40108 1.000 44.47140  ? 213 GLU B CG  1 
ATOM   6015 C CD  . GLU B 1 214 ? -3.37822  -11.38927 -31.72449 1.000 48.94719  ? 213 GLU B CD  1 
ATOM   6016 O OE1 . GLU B 1 214 ? -3.36521  -11.35109 -30.46233 1.000 55.25584  ? 213 GLU B OE1 1 
ATOM   6017 O OE2 . GLU B 1 214 ? -2.48151  -10.87479 -32.45381 1.000 41.81146  ? 213 GLU B OE2 1 
ATOM   6018 N N   . LEU B 1 215 ? -4.09952  -16.83441 -32.16277 1.000 47.60603  ? 214 LEU B N   1 
ATOM   6019 C CA  . LEU B 1 215 ? -4.22357  -18.07065 -31.39657 1.000 41.60722  ? 214 LEU B CA  1 
ATOM   6020 C C   . LEU B 1 215 ? -3.40899  -19.24320 -31.92615 1.000 43.98706  ? 214 LEU B C   1 
ATOM   6021 O O   . LEU B 1 215 ? -2.98477  -20.07962 -31.12836 1.000 45.91312  ? 214 LEU B O   1 
ATOM   6022 C CB  . LEU B 1 215 ? -5.69356  -18.50504 -31.31939 1.000 43.08493  ? 214 LEU B CB  1 
ATOM   6023 C CG  . LEU B 1 215 ? -6.58507  -17.66909 -30.39958 1.000 47.74843  ? 214 LEU B CG  1 
ATOM   6024 C CD1 . LEU B 1 215 ? -8.06179  -18.02986 -30.59995 1.000 41.01542  ? 214 LEU B CD1 1 
ATOM   6025 C CD2 . LEU B 1 215 ? -6.16599  -17.81711 -28.94054 1.000 41.26467  ? 214 LEU B CD2 1 
ATOM   6026 N N   . GLY B 1 216 ? -3.19295  -19.35315 -33.23396 1.000 47.78151  ? 215 GLY B N   1 
ATOM   6027 C CA  . GLY B 1 216 ? -2.57161  -20.55607 -33.76561 1.000 46.57746  ? 215 GLY B CA  1 
ATOM   6028 C C   . GLY B 1 216 ? -3.57908  -21.67728 -33.94025 1.000 48.31508  ? 215 GLY B C   1 
ATOM   6029 O O   . GLY B 1 216 ? -4.56849  -21.73251 -33.20179 1.000 50.60646  ? 215 GLY B O   1 
ATOM   6030 N N   . ALA B 1 217 ? -3.34916  -22.58158 -34.90147 1.000 47.36591  ? 216 ALA B N   1 
ATOM   6031 C CA  . ALA B 1 217 ? -4.39926  -23.52975 -35.27546 1.000 45.05938  ? 216 ALA B CA  1 
ATOM   6032 C C   . ALA B 1 217 ? -4.56202  -24.63717 -34.24522 1.000 48.56252  ? 216 ALA B C   1 
ATOM   6033 O O   . ALA B 1 217 ? -5.66772  -25.18029 -34.09699 1.000 43.52342  ? 216 ALA B O   1 
ATOM   6034 C CB  . ALA B 1 217 ? -4.12153  -24.12457 -36.65637 1.000 36.56671  ? 216 ALA B CB  1 
ATOM   6035 N N   . ASP B 1 218 ? -3.48534  -24.98423 -33.53050 1.000 51.11880  ? 217 ASP B N   1 
ATOM   6036 C CA  . ASP B 1 218 ? -3.61138  -25.92885 -32.42649 1.000 47.96282  ? 217 ASP B CA  1 
ATOM   6037 C C   . ASP B 1 218 ? -4.66272  -25.44201 -31.45204 1.000 47.88237  ? 217 ASP B C   1 
ATOM   6038 O O   . ASP B 1 218 ? -5.70557  -26.07923 -31.26861 1.000 54.75645  ? 217 ASP B O   1 
ATOM   6039 C CB  . ASP B 1 218 ? -2.28557  -26.09821 -31.68767 1.000 53.73985  ? 217 ASP B CB  1 
ATOM   6040 C CG  . ASP B 1 218 ? -1.11365  -26.14070 -32.61222 1.000 72.95607  ? 217 ASP B CG  1 
ATOM   6041 O OD1 . ASP B 1 218 ? -0.93360  -25.14139 -33.35451 1.000 76.72365  ? 217 ASP B OD1 1 
ATOM   6042 O OD2 . ASP B 1 218 ? -0.37890  -27.15824 -32.58937 1.000 84.64726  ? 217 ASP B OD2 1 
ATOM   6043 N N   . THR B 1 219 ? -4.40384  -24.29341 -30.82374 1.000 42.39615  ? 218 THR B N   1 
ATOM   6044 C CA  . THR B 1 219 ? -5.33863  -23.77555 -29.83877 1.000 44.21850  ? 218 THR B CA  1 
ATOM   6045 C C   . THR B 1 219 ? -6.73124  -23.65399 -30.43483 1.000 48.44675  ? 218 THR B C   1 
ATOM   6046 O O   . THR B 1 219 ? -7.73036  -23.97501 -29.77548 1.000 47.67216  ? 218 THR B O   1 
ATOM   6047 C CB  . THR B 1 219 ? -4.85933  -22.42782 -29.31566 1.000 40.98947  ? 218 THR B CB  1 
ATOM   6048 O OG1 . THR B 1 219 ? -3.46667  -22.50890 -29.00705 1.000 47.57583  ? 218 THR B OG1 1 
ATOM   6049 C CG2 . THR B 1 219 ? -5.60757  -22.07850 -28.08271 1.000 37.72281  ? 218 THR B CG2 1 
ATOM   6050 N N   . LEU B 1 220 ? -6.81175  -23.23801 -31.70331 1.000 43.14148  ? 219 LEU B N   1 
ATOM   6051 C CA  . LEU B 1 220 ? -8.10932  -23.08884 -32.34962 1.000 39.41410  ? 219 LEU B CA  1 
ATOM   6052 C C   . LEU B 1 220 ? -8.82370  -24.42483 -32.48524 1.000 41.82728  ? 219 LEU B C   1 
ATOM   6053 O O   . LEU B 1 220 ? -10.03922 -24.50986 -32.25918 1.000 40.26721  ? 219 LEU B O   1 
ATOM   6054 C CB  . LEU B 1 220 ? -7.94087  -22.41365 -33.71020 1.000 42.10781  ? 219 LEU B CB  1 
ATOM   6055 C CG  . LEU B 1 220 ? -8.12739  -20.90476 -33.58255 1.000 44.82893  ? 219 LEU B CG  1 
ATOM   6056 C CD1 . LEU B 1 220 ? -8.47470  -20.29619 -34.88335 1.000 34.68071  ? 219 LEU B CD1 1 
ATOM   6057 C CD2 . LEU B 1 220 ? -9.23920  -20.60668 -32.57602 1.000 48.44660  ? 219 LEU B CD2 1 
ATOM   6058 N N   . ALA B 1 221 ? -8.09016  -25.47948 -32.85246 1.000 38.71316  ? 220 ALA B N   1 
ATOM   6059 C CA  . ALA B 1 221 ? -8.71349  -26.78906 -32.98115 1.000 39.62679  ? 220 ALA B CA  1 
ATOM   6060 C C   . ALA B 1 221 ? -9.22225  -27.30003 -31.63207 1.000 48.78040  ? 220 ALA B C   1 
ATOM   6061 O O   . ALA B 1 221 ? -10.28339 -27.93706 -31.55660 1.000 51.68851  ? 220 ALA B O   1 
ATOM   6062 C CB  . ALA B 1 221 ? -7.72274  -27.77002 -33.58646 1.000 37.95298  ? 220 ALA B CB  1 
ATOM   6063 N N   . ARG B 1 222 ? -8.48120  -27.03489 -30.55414 1.000 40.62427  ? 221 ARG B N   1 
ATOM   6064 C CA  . ARG B 1 222 ? -8.90660  -27.50901 -29.24346 1.000 43.13754  ? 221 ARG B CA  1 
ATOM   6065 C C   . ARG B 1 222 ? -10.14312 -26.75697 -28.75584 1.000 39.84295  ? 221 ARG B C   1 
ATOM   6066 O O   . ARG B 1 222 ? -11.06005 -27.36240 -28.18555 1.000 34.06628  ? 221 ARG B O   1 
ATOM   6067 C CB  . ARG B 1 222 ? -7.75375  -27.37000 -28.25516 1.000 40.35927  ? 221 ARG B CB  1 
ATOM   6068 C CG  . ARG B 1 222 ? -7.96293  -28.09074 -26.95753 1.000 33.38127  ? 221 ARG B CG  1 
ATOM   6069 C CD  . ARG B 1 222 ? -6.79302  -27.81429 -26.04530 1.000 38.34014  ? 221 ARG B CD  1 
ATOM   6070 N NE  . ARG B 1 222 ? -6.74087  -26.41775 -25.62028 1.000 39.56162  ? 221 ARG B NE  1 
ATOM   6071 C CZ  . ARG B 1 222 ? -5.75051  -25.57637 -25.90422 1.000 46.04809  ? 221 ARG B CZ  1 
ATOM   6072 N NH1 . ARG B 1 222 ? -4.71464  -25.94659 -26.64676 1.000 48.27013  ? 221 ARG B NH1 1 
ATOM   6073 N NH2 . ARG B 1 222 ? -5.79799  -24.33085 -25.43003 1.000 43.38626  ? 221 ARG B NH2 1 
ATOM   6074 N N   . PHE B 1 223 ? -10.17142 -25.43375 -28.94791 1.000 37.10917  ? 222 PHE B N   1 
ATOM   6075 C CA  . PHE B 1 223 ? -11.39189 -24.67332 -28.70327 1.000 38.89478  ? 222 PHE B CA  1 
ATOM   6076 C C   . PHE B 1 223 ? -12.55124 -25.25741 -29.50561 1.000 40.92289  ? 222 PHE B C   1 
ATOM   6077 O O   . PHE B 1 223 ? -13.63247 -25.50863 -28.96213 1.000 40.23741  ? 222 PHE B O   1 
ATOM   6078 C CB  . PHE B 1 223 ? -11.20817 -23.19026 -29.07221 1.000 39.70082  ? 222 PHE B CB  1 
ATOM   6079 C CG  . PHE B 1 223 ? -10.25735 -22.41745 -28.18584 1.000 37.01635  ? 222 PHE B CG  1 
ATOM   6080 C CD1 . PHE B 1 223 ? -9.67259  -22.98265 -27.08017 1.000 37.86694  ? 222 PHE B CD1 1 
ATOM   6081 C CD2 . PHE B 1 223 ? -9.96072  -21.09400 -28.47658 1.000 40.99649  ? 222 PHE B CD2 1 
ATOM   6082 C CE1 . PHE B 1 223 ? -8.80258  -22.24131 -26.27672 1.000 37.70546  ? 222 PHE B CE1 1 
ATOM   6083 C CE2 . PHE B 1 223 ? -9.08452  -20.35470 -27.68361 1.000 36.97025  ? 222 PHE B CE2 1 
ATOM   6084 C CZ  . PHE B 1 223 ? -8.51349  -20.93147 -26.58445 1.000 34.38517  ? 222 PHE B CZ  1 
ATOM   6085 N N   . ASP B 1 224 ? -12.34207 -25.46134 -30.81665 1.000 41.69609  ? 223 ASP B N   1 
ATOM   6086 C CA  . ASP B 1 224 ? -13.38505 -26.01905 -31.67955 1.000 40.48353  ? 223 ASP B CA  1 
ATOM   6087 C C   . ASP B 1 224 ? -13.92599 -27.33644 -31.12593 1.000 42.04744  ? 223 ASP B C   1 
ATOM   6088 O O   . ASP B 1 224 ? -15.13324 -27.59452 -31.17240 1.000 42.73881  ? 223 ASP B O   1 
ATOM   6089 C CB  . ASP B 1 224 ? -12.83846 -26.23241 -33.09352 1.000 41.82280  ? 223 ASP B CB  1 
ATOM   6090 C CG  . ASP B 1 224 ? -12.91244 -24.98149 -33.96947 1.000 44.81535  ? 223 ASP B CG  1 
ATOM   6091 O OD1 . ASP B 1 224 ? -13.53444 -23.97740 -33.56354 1.000 41.49535  ? 223 ASP B OD1 1 
ATOM   6092 O OD2 . ASP B 1 224 ? -12.34264 -25.01523 -35.09044 1.000 50.17903  ? 223 ASP B OD2 1 
ATOM   6093 N N   . ARG B 1 225 ? -13.04436 -28.18285 -30.59517 1.000 42.37252  ? 224 ARG B N   1 
ATOM   6094 C CA  . ARG B 1 225 ? -13.48860 -29.43799 -30.00007 1.000 44.66997  ? 224 ARG B CA  1 
ATOM   6095 C C   . ARG B 1 225 ? -14.30718 -29.20926 -28.72520 1.000 47.68593  ? 224 ARG B C   1 
ATOM   6096 O O   . ARG B 1 225 ? -15.28111 -29.92804 -28.48191 1.000 51.39076  ? 224 ARG B O   1 
ATOM   6097 C CB  . ARG B 1 225 ? -12.28204 -30.32520 -29.70639 1.000 43.45099  ? 224 ARG B CB  1 
ATOM   6098 C CG  . ARG B 1 225 ? -11.53161 -30.77772 -30.92332 1.000 39.74887  ? 224 ARG B CG  1 
ATOM   6099 C CD  . ARG B 1 225 ? -10.63205 -31.95818 -30.57633 1.000 44.46186  ? 224 ARG B CD  1 
ATOM   6100 N NE  . ARG B 1 225 ? -9.31269  -31.51639 -30.13883 1.000 50.40887  ? 224 ARG B NE  1 
ATOM   6101 C CZ  . ARG B 1 225 ? -8.34157  -31.11405 -30.95149 1.000 47.10354  ? 224 ARG B CZ  1 
ATOM   6102 N NH1 . ARG B 1 225 ? -8.49907  -31.10142 -32.26486 1.000 46.23367  ? 224 ARG B NH1 1 
ATOM   6103 N NH2 . ARG B 1 225 ? -7.18248  -30.71250 -30.43160 1.000 46.05012  ? 224 ARG B NH2 1 
ATOM   6104 N N   . VAL B 1 226 ? -13.91850 -28.24405 -27.88027 1.000 43.59495  ? 225 VAL B N   1 
ATOM   6105 C CA  . VAL B 1 226 ? -14.75770 -27.90514 -26.73260 1.000 41.01128  ? 225 VAL B CA  1 
ATOM   6106 C C   . VAL B 1 226 ? -16.17997 -27.64393 -27.19262 1.000 42.34031  ? 225 VAL B C   1 
ATOM   6107 O O   . VAL B 1 226 ? -17.13560 -28.21315 -26.66069 1.000 53.23294  ? 225 VAL B O   1 
ATOM   6108 C CB  . VAL B 1 226 ? -14.20321 -26.69061 -25.96541 1.000 41.81017  ? 225 VAL B CB  1 
ATOM   6109 C CG1 . VAL B 1 226 ? -15.14526 -26.33607 -24.80388 1.000 38.80375  ? 225 VAL B CG1 1 
ATOM   6110 C CG2 . VAL B 1 226 ? -12.81743 -26.95480 -25.46212 1.000 39.09963  ? 225 VAL B CG2 1 
ATOM   6111 N N   . LEU B 1 227 ? -16.34051 -26.77669 -28.19249 1.000 45.46166  ? 226 LEU B N   1 
ATOM   6112 C CA  . LEU B 1 227 ? -17.67767 -26.47533 -28.70558 1.000 50.27427  ? 226 LEU B CA  1 
ATOM   6113 C C   . LEU B 1 227 ? -18.33998 -27.72061 -29.29595 1.000 53.06618  ? 226 LEU B C   1 
ATOM   6114 O O   . LEU B 1 227 ? -19.54354 -27.94800 -29.10730 1.000 50.72612  ? 226 LEU B O   1 
ATOM   6115 C CB  . LEU B 1 227 ? -17.59676 -25.35951 -29.75223 1.000 45.08620  ? 226 LEU B CB  1 
ATOM   6116 C CG  . LEU B 1 227 ? -17.41929 -23.91434 -29.28055 1.000 43.18428  ? 226 LEU B CG  1 
ATOM   6117 C CD1 . LEU B 1 227 ? -17.55361 -22.94157 -30.46162 1.000 40.41662  ? 226 LEU B CD1 1 
ATOM   6118 C CD2 . LEU B 1 227 ? -18.43387 -23.59877 -28.19721 1.000 38.90521  ? 226 LEU B CD2 1 
ATOM   6119 N N   . THR B 1 228 ? -17.55945 -28.54933 -29.99816 1.000 55.50238  ? 227 THR B N   1 
ATOM   6120 C CA  . THR B 1 228 ? -18.11973 -29.70075 -30.69984 1.000 52.07452  ? 227 THR B CA  1 
ATOM   6121 C C   . THR B 1 228 ? -18.63966 -30.75535 -29.72896 1.000 52.38574  ? 227 THR B C   1 
ATOM   6122 O O   . THR B 1 228 ? -19.78881 -31.19314 -29.83858 1.000 55.94431  ? 227 THR B O   1 
ATOM   6123 C CB  . THR B 1 228 ? -17.07512 -30.28484 -31.65201 1.000 52.12358  ? 227 THR B CB  1 
ATOM   6124 O OG1 . THR B 1 228 ? -17.05822 -29.51799 -32.87183 1.000 48.74703  ? 227 THR B OG1 1 
ATOM   6125 C CG2 . THR B 1 228 ? -17.36494 -31.74571 -31.93749 1.000 57.06657  ? 227 THR B CG2 1 
ATOM   6126 N N   . GLY B 1 229 ? -17.82692 -31.15534 -28.75508 1.000 51.43843  ? 228 GLY B N   1 
ATOM   6127 C CA  . GLY B 1 229 ? -18.24821 -32.15074 -27.78466 1.000 52.28382  ? 228 GLY B CA  1 
ATOM   6128 C C   . GLY B 1 229 ? -19.36892 -31.71141 -26.85771 1.000 56.12175  ? 228 GLY B C   1 
ATOM   6129 O O   . GLY B 1 229 ? -19.63874 -32.35914 -25.83951 1.000 61.10714  ? 228 GLY B O   1 
ATOM   6130 N N   . ARG B 1 230 ? -20.01769 -30.59801 -27.18615 1.000 52.32857  ? 229 ARG B N   1 
ATOM   6131 C CA  . ARG B 1 230 ? -21.20531 -30.15113 -26.47359 1.000 57.52885  ? 229 ARG B CA  1 
ATOM   6132 C C   . ARG B 1 230 ? -22.39885 -30.03945 -27.41055 1.000 56.08233  ? 229 ARG B C   1 
ATOM   6133 O O   . ARG B 1 230 ? -23.43732 -29.49047 -27.02107 1.000 58.25574  ? 229 ARG B O   1 
ATOM   6134 C CB  . ARG B 1 230 ? -20.93877 -28.81352 -25.76842 1.000 49.97175  ? 229 ARG B CB  1 
ATOM   6135 C CG  . ARG B 1 230 ? -19.65389 -28.81677 -24.96497 1.000 53.08870  ? 229 ARG B CG  1 
ATOM   6136 C CD  . ARG B 1 230 ? -19.66353 -27.80980 -23.81604 1.000 63.88298  ? 229 ARG B CD  1 
ATOM   6137 N NE  . ARG B 1 230 ? -18.91612 -28.31839 -22.66878 1.000 71.13701  ? 229 ARG B NE  1 
ATOM   6138 C CZ  . ARG B 1 230 ? -18.33376 -27.56386 -21.74407 1.000 73.22064  ? 229 ARG B CZ  1 
ATOM   6139 N NH1 . ARG B 1 230 ? -18.36450 -26.23991 -21.81042 1.000 68.75444  ? 229 ARG B NH1 1 
ATOM   6140 N NH2 . ARG B 1 230 ? -17.71045 -28.15345 -20.72193 1.000 65.51262  ? 229 ARG B NH2 1 
ATOM   6141 N N   . GLY B 1 231 ? -22.27371 -30.54366 -28.63536 1.000 50.28671  ? 230 GLY B N   1 
ATOM   6142 C CA  . GLY B 1 231 ? -23.34472 -30.48024 -29.60693 1.000 53.56075  ? 230 GLY B CA  1 
ATOM   6143 C C   . GLY B 1 231 ? -23.43504 -29.18409 -30.36820 1.000 53.86623  ? 230 GLY B C   1 
ATOM   6144 O O   . GLY B 1 231 ? -24.46175 -28.92293 -31.00726 1.000 59.55991  ? 230 GLY B O   1 
ATOM   6145 N N   . LEU B 1 232 ? -22.39721 -28.36643 -30.32599 1.000 50.80545  ? 231 LEU B N   1 
ATOM   6146 C CA  . LEU B 1 232 ? -22.46119 -27.01668 -30.84718 1.000 52.75009  ? 231 LEU B CA  1 
ATOM   6147 C C   . LEU B 1 232 ? -21.59944 -26.90465 -32.09253 1.000 51.42847  ? 231 LEU B C   1 
ATOM   6148 O O   . LEU B 1 232 ? -20.58687 -27.59324 -32.22459 1.000 54.29418  ? 231 LEU B O   1 
ATOM   6149 C CB  . LEU B 1 232 ? -21.99899 -26.00040 -29.79727 1.000 52.80839  ? 231 LEU B CB  1 
ATOM   6150 C CG  . LEU B 1 232 ? -22.69268 -26.01979 -28.43675 1.000 48.95041  ? 231 LEU B CG  1 
ATOM   6151 C CD1 . LEU B 1 232 ? -22.19288 -24.86351 -27.58623 1.000 48.78536  ? 231 LEU B CD1 1 
ATOM   6152 C CD2 . LEU B 1 232 ? -24.18586 -25.93675 -28.60542 1.000 46.16927  ? 231 LEU B CD2 1 
ATOM   6153 N N   . ASP B 1 233 ? -22.01556 -26.02195 -33.00236 1.000 49.96153  ? 232 ASP B N   1 
ATOM   6154 C CA  . ASP B 1 233 ? -21.27811 -25.76127 -34.23210 1.000 50.33966  ? 232 ASP B CA  1 
ATOM   6155 C C   . ASP B 1 233 ? -20.31918 -24.60822 -33.98819 1.000 48.38139  ? 232 ASP B C   1 
ATOM   6156 O O   . ASP B 1 233 ? -20.77684 -23.47450 -33.78113 1.000 51.41075  ? 232 ASP B O   1 
ATOM   6157 C CB  . ASP B 1 233 ? -22.23955 -25.41208 -35.36835 1.000 54.22622  ? 232 ASP B CB  1 
ATOM   6158 C CG  . ASP B 1 233 ? -21.59401 -25.49282 -36.76223 1.000 56.56795  ? 232 ASP B CG  1 
ATOM   6159 O OD1 . ASP B 1 233 ? -20.34620 -25.43367 -36.88160 1.000 58.18391  ? 232 ASP B OD1 1 
ATOM   6160 O OD2 . ASP B 1 233 ? -22.35287 -25.59097 -37.75499 1.000 56.49495  ? 232 ASP B OD2 1 
ATOM   6161 N N   . PRO B 1 234 ? -19.00970 -24.83054 -34.00614 1.000 46.27802  ? 233 PRO B N   1 
ATOM   6162 C CA  . PRO B 1 234 ? -18.06611 -23.70135 -33.98844 1.000 42.78492  ? 233 PRO B CA  1 
ATOM   6163 C C   . PRO B 1 234 ? -18.45687 -22.57790 -34.94311 1.000 45.82324  ? 233 PRO B C   1 
ATOM   6164 O O   . PRO B 1 234 ? -18.23943 -21.39604 -34.65802 1.000 46.00953  ? 233 PRO B O   1 
ATOM   6165 C CB  . PRO B 1 234 ? -16.74701 -24.35380 -34.40507 1.000 35.15672  ? 233 PRO B CB  1 
ATOM   6166 C CG  . PRO B 1 234 ? -16.86942 -25.76933 -33.87901 1.000 45.74850  ? 233 PRO B CG  1 
ATOM   6167 C CD  . PRO B 1 234 ? -18.33039 -26.13896 -33.95673 1.000 46.48137  ? 233 PRO B CD  1 
ATOM   6168 N N   . ALA B 1 235 ? -19.07332 -22.93124 -36.07094 1.000 49.43047  ? 234 ALA B N   1 
ATOM   6169 C CA  . ALA B 1 235 ? -19.44759 -21.92243 -37.05200 1.000 45.50951  ? 234 ALA B CA  1 
ATOM   6170 C C   . ALA B 1 235 ? -20.44919 -20.92052 -36.49799 1.000 44.86778  ? 234 ALA B C   1 
ATOM   6171 O O   . ALA B 1 235 ? -20.60371 -19.83887 -37.07096 1.000 46.01718  ? 234 ALA B O   1 
ATOM   6172 C CB  . ALA B 1 235 ? -20.00845 -22.59257 -38.30454 1.000 40.07676  ? 234 ALA B CB  1 
ATOM   6173 N N   . SER B 1 236 ? -21.11720 -21.23777 -35.39461 1.000 43.67227  ? 235 SER B N   1 
ATOM   6174 C CA  . SER B 1 236 ? -22.09883 -20.32788 -34.82253 1.000 40.90057  ? 235 SER B CA  1 
ATOM   6175 C C   . SER B 1 236 ? -21.49773 -19.31783 -33.85187 1.000 42.17521  ? 235 SER B C   1 
ATOM   6176 O O   . SER B 1 236 ? -22.24946 -18.53501 -33.26231 1.000 42.16588  ? 235 SER B O   1 
ATOM   6177 C CB  . SER B 1 236 ? -23.19883 -21.11902 -34.11054 1.000 38.10737  ? 235 SER B CB  1 
ATOM   6178 O OG  . SER B 1 236 ? -24.08073 -21.74637 -35.03052 1.000 32.27823  ? 235 SER B OG  1 
ATOM   6179 N N   . TYR B 1 237 ? -20.17440 -19.29571 -33.67512 1.000 42.25500  ? 236 TYR B N   1 
ATOM   6180 C CA  . TYR B 1 237 ? -19.56248 -18.49788 -32.62146 1.000 40.02646  ? 236 TYR B CA  1 
ATOM   6181 C C   . TYR B 1 237 ? -18.41813 -17.64932 -33.15025 1.000 39.14396  ? 236 TYR B C   1 
ATOM   6182 O O   . TYR B 1 237 ? -17.79396 -17.97010 -34.16295 1.000 42.03841  ? 236 TYR B O   1 
ATOM   6183 C CB  . TYR B 1 237 ? -19.04938 -19.39977 -31.47712 1.000 41.99987  ? 236 TYR B CB  1 
ATOM   6184 C CG  . TYR B 1 237 ? -20.18925 -20.08735 -30.79368 1.000 42.48334  ? 236 TYR B CG  1 
ATOM   6185 C CD1 . TYR B 1 237 ? -20.72082 -21.26858 -31.30866 1.000 44.65321  ? 236 TYR B CD1 1 
ATOM   6186 C CD2 . TYR B 1 237 ? -20.78636 -19.52280 -29.68106 1.000 37.40407  ? 236 TYR B CD2 1 
ATOM   6187 C CE1 . TYR B 1 237 ? -21.80359 -21.87916 -30.71403 1.000 45.55786  ? 236 TYR B CE1 1 
ATOM   6188 C CE2 . TYR B 1 237 ? -21.86840 -20.11855 -29.07794 1.000 44.26694  ? 236 TYR B CE2 1 
ATOM   6189 C CZ  . TYR B 1 237 ? -22.38088 -21.29850 -29.59600 1.000 47.33995  ? 236 TYR B CZ  1 
ATOM   6190 O OH  . TYR B 1 237 ? -23.46635 -21.89742 -28.99327 1.000 38.11658  ? 236 TYR B OH  1 
ATOM   6191 N N   . TYR B 1 238 ? -18.16236 -16.54979 -32.45268 1.000 39.50035  ? 237 TYR B N   1 
ATOM   6192 C CA  . TYR B 1 238 ? -16.84533 -15.93378 -32.43124 1.000 38.15178  ? 237 TYR B CA  1 
ATOM   6193 C C   . TYR B 1 238 ? -16.13505 -16.31773 -31.14218 1.000 36.25683  ? 237 TYR B C   1 
ATOM   6194 O O   . TYR B 1 238 ? -16.76694 -16.60199 -30.12359 1.000 35.69763  ? 237 TYR B O   1 
ATOM   6195 C CB  . TYR B 1 238 ? -16.91488 -14.41669 -32.49546 1.000 36.84679  ? 237 TYR B CB  1 
ATOM   6196 C CG  . TYR B 1 238 ? -17.71400 -13.84068 -33.61812 1.000 41.14960  ? 237 TYR B CG  1 
ATOM   6197 C CD1 . TYR B 1 238 ? -17.34893 -14.05077 -34.94615 1.000 42.71763  ? 237 TYR B CD1 1 
ATOM   6198 C CD2 . TYR B 1 238 ? -18.81651 -13.04324 -33.35243 1.000 38.90362  ? 237 TYR B CD2 1 
ATOM   6199 C CE1 . TYR B 1 238 ? -18.07662 -13.49084 -35.97180 1.000 38.78447  ? 237 TYR B CE1 1 
ATOM   6200 C CE2 . TYR B 1 238 ? -19.54386 -12.48251 -34.36717 1.000 41.53587  ? 237 TYR B CE2 1 
ATOM   6201 C CZ  . TYR B 1 238 ? -19.17131 -12.70700 -35.67275 1.000 38.12474  ? 237 TYR B CZ  1 
ATOM   6202 O OH  . TYR B 1 238 ? -19.91169 -12.12800 -36.66742 1.000 44.97359  ? 237 TYR B OH  1 
ATOM   6203 N N   . TYR B 1 239 ? -14.81462 -16.31174 -31.18708 1.000 36.08679  ? 238 TYR B N   1 
ATOM   6204 C CA  . TYR B 1 239 ? -14.02075 -16.46076 -29.98284 1.000 32.98758  ? 238 TYR B CA  1 
ATOM   6205 C C   . TYR B 1 239 ? -13.63305 -15.08068 -29.49184 1.000 33.75380  ? 238 TYR B C   1 
ATOM   6206 O O   . TYR B 1 239 ? -13.38208 -14.17968 -30.28895 1.000 36.87401  ? 238 TYR B O   1 
ATOM   6207 C CB  . TYR B 1 239 ? -12.78521 -17.30410 -30.24492 1.000 36.05027  ? 238 TYR B CB  1 
ATOM   6208 C CG  . TYR B 1 239 ? -13.12553 -18.74587 -30.45653 1.000 35.68144  ? 238 TYR B CG  1 
ATOM   6209 C CD1 . TYR B 1 239 ? -13.97205 -19.40350 -29.58131 1.000 35.47374  ? 238 TYR B CD1 1 
ATOM   6210 C CD2 . TYR B 1 239 ? -12.61194 -19.44777 -31.53906 1.000 32.04883  ? 238 TYR B CD2 1 
ATOM   6211 C CE1 . TYR B 1 239 ? -14.29295 -20.72021 -29.77625 1.000 38.73235  ? 238 TYR B CE1 1 
ATOM   6212 C CE2 . TYR B 1 239 ? -12.92266 -20.75868 -31.73886 1.000 30.23262  ? 238 TYR B CE2 1 
ATOM   6213 C CZ  . TYR B 1 239 ? -13.76466 -21.39498 -30.86282 1.000 35.95910  ? 238 TYR B CZ  1 
ATOM   6214 O OH  . TYR B 1 239 ? -14.07882 -22.71820 -31.06825 1.000 38.12434  ? 238 TYR B OH  1 
ATOM   6215 N N   . MET B 1 240 ? -13.58287 -14.91100 -28.17753 1.000 39.53528  ? 239 MET B N   1 
ATOM   6216 C CA  . MET B 1 240 ? -13.52100 -13.56577 -27.69937 1.000 39.38718  ? 239 MET B CA  1 
ATOM   6217 C C   . MET B 1 240 ? -12.75526 -13.58706 -26.38250 1.000 40.56857  ? 239 MET B C   1 
ATOM   6218 O O   . MET B 1 240 ? -13.08946 -14.41245 -25.51843 1.000 41.87670  ? 239 MET B O   1 
ATOM   6219 C CB  . MET B 1 240 ? -14.94981 -13.05939 -27.50978 1.000 38.23269  ? 239 MET B CB  1 
ATOM   6220 C CG  . MET B 1 240 ? -15.06878 -11.58904 -27.44634 1.000 42.87118  ? 239 MET B CG  1 
ATOM   6221 S SD  . MET B 1 240 ? -16.19833 -11.05262 -26.17331 1.000 39.61096  ? 239 MET B SD  1 
ATOM   6222 C CE  . MET B 1 240 ? -17.75016 -11.39394 -26.95159 1.000 45.40233  ? 239 MET B CE  1 
ATOM   6223 N N   . PRO B 1 241 ? -11.71893 -12.75056 -26.21450 1.000 41.15497  ? 240 PRO B N   1 
ATOM   6224 C CA  . PRO B 1 241 ? -10.95443 -12.72970 -24.94932 1.000 37.06892  ? 240 PRO B CA  1 
ATOM   6225 C C   . PRO B 1 241 ? -11.66088 -11.95679 -23.83957 1.000 35.20686  ? 240 PRO B C   1 
ATOM   6226 O O   . PRO B 1 241 ? -12.31634 -10.94461 -24.08651 1.000 39.67406  ? 240 PRO B O   1 
ATOM   6227 C CB  . PRO B 1 241 ? -9.65042  -12.02841 -25.34316 1.000 37.55388  ? 240 PRO B CB  1 
ATOM   6228 C CG  . PRO B 1 241 ? -10.04123 -11.14174 -26.46785 1.000 37.49874  ? 240 PRO B CG  1 
ATOM   6229 C CD  . PRO B 1 241 ? -11.14900 -11.84422 -27.22253 1.000 36.93964  ? 240 PRO B CD  1 
ATOM   6230 N N   . VAL B 1 242 ? -11.52023 -12.44201 -22.60216 1.000 34.84798  ? 241 VAL B N   1 
ATOM   6231 C CA  . VAL B 1 242 ? -12.10945 -11.82128 -21.41510 1.000 33.09392  ? 241 VAL B CA  1 
ATOM   6232 C C   . VAL B 1 242 ? -11.02824 -11.68234 -20.35616 1.000 32.77986  ? 241 VAL B C   1 
ATOM   6233 O O   . VAL B 1 242 ? -10.25427 -12.62037 -20.12927 1.000 30.42038  ? 241 VAL B O   1 
ATOM   6234 C CB  . VAL B 1 242 ? -13.28883 -12.65113 -20.86834 1.000 31.19662  ? 241 VAL B CB  1 
ATOM   6235 C CG1 . VAL B 1 242 ? -13.98675 -11.94355 -19.71944 1.000 23.84535  ? 241 VAL B CG1 1 
ATOM   6236 C CG2 . VAL B 1 242 ? -14.25306 -12.95659 -21.98943 1.000 34.68757  ? 241 VAL B CG2 1 
ATOM   6237 N N   . HIS B 1 243 ? -10.95890 -10.51148 -19.71932 1.000 34.71504  ? 242 HIS B N   1 
ATOM   6238 C CA  . HIS B 1 243 ? -10.02907 -10.33743 -18.60157 1.000 32.45898  ? 242 HIS B CA  1 
ATOM   6239 C C   . HIS B 1 243 ? -10.41035 -11.29525 -17.47524 1.000 33.34188  ? 242 HIS B C   1 
ATOM   6240 O O   . HIS B 1 243 ? -11.59956 -11.40047 -17.13919 1.000 34.11510  ? 242 HIS B O   1 
ATOM   6241 C CB  . HIS B 1 243 ? -10.05673 -8.89568  -18.10110 1.000 31.51633  ? 242 HIS B CB  1 
ATOM   6242 C CG  . HIS B 1 243 ? -8.94171  -8.54178  -17.15895 1.000 33.74666  ? 242 HIS B CG  1 
ATOM   6243 N ND1 . HIS B 1 243 ? -8.85978  -9.03524  -15.87503 1.000 40.27358  ? 242 HIS B ND1 1 
ATOM   6244 C CD2 . HIS B 1 243 ? -7.89258  -7.69461  -17.29560 1.000 37.53574  ? 242 HIS B CD2 1 
ATOM   6245 C CE1 . HIS B 1 243 ? -7.79382  -8.53339  -15.27218 1.000 35.71463  ? 242 HIS B CE1 1 
ATOM   6246 N NE2 . HIS B 1 243 ? -7.19109  -7.71232  -16.11184 1.000 35.26606  ? 242 HIS B NE2 1 
ATOM   6247 N N   . PRO B 1 244 ? -9.45071  -12.01715 -16.88072 1.000 34.35548  ? 243 PRO B N   1 
ATOM   6248 C CA  . PRO B 1 244 ? -9.80903  -12.98423 -15.82772 1.000 26.02624  ? 243 PRO B CA  1 
ATOM   6249 C C   . PRO B 1 244 ? -10.61915 -12.36773 -14.70411 1.000 33.72930  ? 243 PRO B C   1 
ATOM   6250 O O   . PRO B 1 244 ? -11.57627 -12.98990 -14.22229 1.000 37.27827  ? 243 PRO B O   1 
ATOM   6251 C CB  . PRO B 1 244 ? -8.45375  -13.47463 -15.31838 1.000 23.17773  ? 243 PRO B CB  1 
ATOM   6252 C CG  . PRO B 1 244 ? -7.47238  -13.06642 -16.32142 1.000 30.71558  ? 243 PRO B CG  1 
ATOM   6253 C CD  . PRO B 1 244 ? -7.99453  -11.86473 -17.02366 1.000 33.75548  ? 243 PRO B CD  1 
ATOM   6254 N N   . TRP B 1 245 ? -10.26185 -11.15067 -14.27676 1.000 32.82133  ? 244 TRP B N   1 
ATOM   6255 C CA  . TRP B 1 245 ? -11.03480 -10.44886 -13.25304 1.000 31.09789  ? 244 TRP B CA  1 
ATOM   6256 C C   . TRP B 1 245 ? -12.47167 -10.23961 -13.69572 1.000 33.45858  ? 244 TRP B C   1 
ATOM   6257 O O   . TRP B 1 245 ? -13.40877 -10.53038 -12.94430 1.000 33.26049  ? 244 TRP B O   1 
ATOM   6258 C CB  . TRP B 1 245 ? -10.38297 -9.09970  -12.92891 1.000 36.20663  ? 244 TRP B CB  1 
ATOM   6259 C CG  . TRP B 1 245 ? -10.99930 -8.35072  -11.74723 1.000 39.27971  ? 244 TRP B CG  1 
ATOM   6260 C CD1 . TRP B 1 245 ? -10.55693 -8.34548  -10.44372 1.000 35.57355  ? 244 TRP B CD1 1 
ATOM   6261 C CD2 . TRP B 1 245 ? -12.15027 -7.49592  -11.77754 1.000 37.73979  ? 244 TRP B CD2 1 
ATOM   6262 N NE1 . TRP B 1 245 ? -11.36938 -7.54537  -9.67227  1.000 34.19797  ? 244 TRP B NE1 1 
ATOM   6263 C CE2 . TRP B 1 245 ? -12.35240 -7.01638  -10.46236 1.000 31.19436  ? 244 TRP B CE2 1 
ATOM   6264 C CE3 . TRP B 1 245 ? -13.02798 -7.09184  -12.78668 1.000 31.89588  ? 244 TRP B CE3 1 
ATOM   6265 C CZ2 . TRP B 1 245 ? -13.38020 -6.15863  -10.14072 1.000 29.43000  ? 244 TRP B CZ2 1 
ATOM   6266 C CZ3 . TRP B 1 245 ? -14.05395 -6.23856  -12.46339 1.000 34.54891  ? 244 TRP B CZ3 1 
ATOM   6267 C CH2 . TRP B 1 245 ? -14.22196 -5.77844  -11.14879 1.000 38.14824  ? 244 TRP B CH2 1 
ATOM   6268 N N   . GLN B 1 246 ? -12.66102 -9.72549  -14.92346 1.000 39.38954  ? 245 GLN B N   1 
ATOM   6269 C CA  . GLN B 1 246 ? -14.00321 -9.43712  -15.42435 1.000 31.68680  ? 245 GLN B CA  1 
ATOM   6270 C C   . GLN B 1 246 ? -14.82567 -10.70423 -15.57563 1.000 32.42489  ? 245 GLN B C   1 
ATOM   6271 O O   . GLN B 1 246 ? -16.02187 -10.72294 -15.24801 1.000 33.12730  ? 245 GLN B O   1 
ATOM   6272 C CB  . GLN B 1 246 ? -13.93286 -8.71422  -16.74826 1.000 21.76444  ? 245 GLN B CB  1 
ATOM   6273 C CG  . GLN B 1 246 ? -15.27922 -8.25460  -17.17014 1.000 29.20723  ? 245 GLN B CG  1 
ATOM   6274 C CD  . GLN B 1 246 ? -15.51041 -6.80556  -16.82317 1.000 35.48601  ? 245 GLN B CD  1 
ATOM   6275 O OE1 . GLN B 1 246 ? -14.81835 -6.24832  -15.97768 1.000 33.35404  ? 245 GLN B OE1 1 
ATOM   6276 N NE2 . GLN B 1 246 ? -16.48033 -6.17636  -17.49013 1.000 38.39972  ? 245 GLN B NE2 1 
ATOM   6277 N N   . TRP B 1 247 ? -14.20508 -11.77511 -16.07040 1.000 30.99340  ? 246 TRP B N   1 
ATOM   6278 C CA  . TRP B 1 247 ? -14.88933 -13.05970 -16.09211 1.000 32.54796  ? 246 TRP B CA  1 
ATOM   6279 C C   . TRP B 1 247 ? -15.46782 -13.37250 -14.72564 1.000 34.27597  ? 246 TRP B C   1 
ATOM   6280 O O   . TRP B 1 247 ? -16.68807 -13.46064 -14.55991 1.000 35.82024  ? 246 TRP B O   1 
ATOM   6281 C CB  . TRP B 1 247 ? -13.94803 -14.17930 -16.52362 1.000 31.26935  ? 246 TRP B CB  1 
ATOM   6282 C CG  . TRP B 1 247 ? -14.68087 -15.45360 -16.50602 1.000 31.37337  ? 246 TRP B CG  1 
ATOM   6283 C CD1 . TRP B 1 247 ? -14.53630 -16.46834 -15.61899 1.000 33.58406  ? 246 TRP B CD1 1 
ATOM   6284 C CD2 . TRP B 1 247 ? -15.73547 -15.84157 -17.39645 1.000 36.14128  ? 246 TRP B CD2 1 
ATOM   6285 N NE1 . TRP B 1 247 ? -15.42068 -17.49124 -15.91382 1.000 28.85127  ? 246 TRP B NE1 1 
ATOM   6286 C CE2 . TRP B 1 247 ? -16.17391 -17.12334 -16.99381 1.000 28.32081  ? 246 TRP B CE2 1 
ATOM   6287 C CE3 . TRP B 1 247 ? -16.33812 -15.23831 -18.50978 1.000 36.99407  ? 246 TRP B CE3 1 
ATOM   6288 C CZ2 . TRP B 1 247 ? -17.18861 -17.80367 -17.65068 1.000 30.01303  ? 246 TRP B CZ2 1 
ATOM   6289 C CZ3 . TRP B 1 247 ? -17.35049 -15.92094 -19.16400 1.000 37.16144  ? 246 TRP B CZ3 1 
ATOM   6290 C CH2 . TRP B 1 247 ? -17.76438 -17.19202 -18.73406 1.000 34.08315  ? 246 TRP B CH2 1 
ATOM   6291 N N   . ALA B 1 248 ? -14.58528 -13.45911 -13.72293 1.000 35.54100  ? 247 ALA B N   1 
ATOM   6292 C CA  . ALA B 1 248 ? -14.95516 -13.90075 -12.38057 1.000 33.92477  ? 247 ALA B CA  1 
ATOM   6293 C C   . ALA B 1 248 ? -16.00400 -13.00041 -11.74277 1.000 36.16950  ? 247 ALA B C   1 
ATOM   6294 O O   . ALA B 1 248 ? -17.04149 -13.47826 -11.26585 1.000 33.54350  ? 247 ALA B O   1 
ATOM   6295 C CB  . ALA B 1 248 ? -13.71263 -13.94852 -11.49953 1.000 33.12524  ? 247 ALA B CB  1 
ATOM   6296 N N   . GLU B 1 249 ? -15.73678 -11.69496 -11.69173 1.000 34.77326  ? 248 GLU B N   1 
ATOM   6297 C CA  . GLU B 1 249 ? -16.61118 -10.80951 -10.93800 1.000 33.85651  ? 248 GLU B CA  1 
ATOM   6298 C C   . GLU B 1 249 ? -17.87017 -10.44703 -11.70387 1.000 35.02623  ? 248 GLU B C   1 
ATOM   6299 O O   . GLU B 1 249 ? -18.92752 -10.29585 -11.09443 1.000 33.82744  ? 248 GLU B O   1 
ATOM   6300 C CB  . GLU B 1 249 ? -15.86004 -9.54339  -10.53841 1.000 38.36032  ? 248 GLU B CB  1 
ATOM   6301 C CG  . GLU B 1 249 ? -14.55414 -9.82054  -9.77801  1.000 42.58663  ? 248 GLU B CG  1 
ATOM   6302 C CD  . GLU B 1 249 ? -14.73966 -9.76022  -8.26709  1.000 52.48167  ? 248 GLU B CD  1 
ATOM   6303 O OE1 . GLU B 1 249 ? -15.85697 -9.34669  -7.81461  1.000 42.67950  ? 248 GLU B OE1 1 
ATOM   6304 O OE2 . GLU B 1 249 ? -13.76108 -10.11650 -7.55069  1.000 52.81422  ? 248 GLU B OE2 1 
ATOM   6305 N N   . LYS B 1 250 ? -17.80364 -10.33307 -13.03078 1.000 40.84458  ? 249 LYS B N   1 
ATOM   6306 C CA  . LYS B 1 250 ? -18.89800 -9.71742  -13.77524 1.000 32.63298  ? 249 LYS B CA  1 
ATOM   6307 C C   . LYS B 1 250 ? -19.59881 -10.68094 -14.72017 1.000 36.57349  ? 249 LYS B C   1 
ATOM   6308 O O   . LYS B 1 250 ? -20.81667 -10.86348 -14.59478 1.000 37.73544  ? 249 LYS B O   1 
ATOM   6309 C CB  . LYS B 1 250 ? -18.36871 -8.49495  -14.52025 1.000 33.67498  ? 249 LYS B CB  1 
ATOM   6310 C CG  . LYS B 1 250 ? -18.07007 -7.33490  -13.57133 1.000 36.47442  ? 249 LYS B CG  1 
ATOM   6311 C CD  . LYS B 1 250 ? -19.23897 -7.11901  -12.62549 1.000 32.10567  ? 249 LYS B CD  1 
ATOM   6312 C CE  . LYS B 1 250 ? -19.08046 -5.85115  -11.82418 1.000 33.69743  ? 249 LYS B CE  1 
ATOM   6313 N NZ  . LYS B 1 250 ? -20.36053 -5.10249  -11.75167 1.000 41.28141  ? 249 LYS B NZ  1 
ATOM   6314 N N   . ILE B 1 251 ? -18.87660 -11.31970 -15.64703 1.000 37.36272  ? 250 ILE B N   1 
ATOM   6315 C CA  . ILE B 1 251 ? -19.54552 -12.06994 -16.71315 1.000 39.57089  ? 250 ILE B CA  1 
ATOM   6316 C C   . ILE B 1 251 ? -20.25768 -13.29114 -16.14897 1.000 34.78331  ? 250 ILE B C   1 
ATOM   6317 O O   . ILE B 1 251 ? -21.41979 -13.55371 -16.47730 1.000 34.70881  ? 250 ILE B O   1 
ATOM   6318 C CB  . ILE B 1 251 ? -18.55675 -12.48920 -17.82243 1.000 42.35080  ? 250 ILE B CB  1 
ATOM   6319 C CG1 . ILE B 1 251 ? -17.61613 -11.35080 -18.24158 1.000 38.13896  ? 250 ILE B CG1 1 
ATOM   6320 C CG2 . ILE B 1 251 ? -19.32843 -13.00230 -19.02595 1.000 38.13281  ? 250 ILE B CG2 1 
ATOM   6321 C CD1 . ILE B 1 251 ? -18.31495 -10.21789 -18.91246 1.000 41.12963  ? 250 ILE B CD1 1 
ATOM   6322 N N   . ALA B 1 252 ? -19.56135 -14.06898 -15.31450 1.000 32.92672  ? 251 ALA B N   1 
ATOM   6323 C CA  . ALA B 1 252 ? -20.09491 -15.35752 -14.87459 1.000 33.82977  ? 251 ALA B CA  1 
ATOM   6324 C C   . ALA B 1 252 ? -21.37132 -15.19960 -14.04337 1.000 38.29842  ? 251 ALA B C   1 
ATOM   6325 O O   . ALA B 1 252 ? -22.29675 -16.01240 -14.15652 1.000 34.13157  ? 251 ALA B O   1 
ATOM   6326 C CB  . ALA B 1 252 ? -19.03482 -16.12067 -14.08930 1.000 25.44894  ? 251 ALA B CB  1 
ATOM   6327 N N   . ARG B 1 253 ? -21.45220 -14.15804 -13.21257 1.000 34.34132  ? 252 ARG B N   1 
ATOM   6328 C CA  . ARG B 1 253 ? -22.64871 -13.98579 -12.40146 1.000 33.01077  ? 252 ARG B CA  1 
ATOM   6329 C C   . ARG B 1 253 ? -23.78598 -13.36120 -13.20179 1.000 37.05229  ? 252 ARG B C   1 
ATOM   6330 O O   . ARG B 1 253 ? -24.91445 -13.86777 -13.17849 1.000 37.74298  ? 252 ARG B O   1 
ATOM   6331 C CB  . ARG B 1 253 ? -22.32913 -13.14056 -11.16979 1.000 38.18437  ? 252 ARG B CB  1 
ATOM   6332 C CG  . ARG B 1 253 ? -21.02108 -13.49836 -10.51785 1.000 38.08467  ? 252 ARG B CG  1 
ATOM   6333 C CD  . ARG B 1 253 ? -21.15393 -13.59416 -9.01563  1.000 35.24159  ? 252 ARG B CD  1 
ATOM   6334 N NE  . ARG B 1 253 ? -22.38709 -14.23761 -8.58153  1.000 37.18085  ? 252 ARG B NE  1 
ATOM   6335 C CZ  . ARG B 1 253 ? -22.99497 -13.97288 -7.43316  1.000 36.62328  ? 252 ARG B CZ  1 
ATOM   6336 N NH1 . ARG B 1 253 ? -22.56551 -13.01420 -6.63057  1.000 33.05564  ? 252 ARG B NH1 1 
ATOM   6337 N NH2 . ARG B 1 253 ? -24.04629 -14.70206 -7.07110  1.000 41.58852  ? 252 ARG B NH2 1 
ATOM   6338 N N   . ILE B 1 254 ? -23.51003 -12.25231 -13.89897 1.000 34.43215  ? 253 ILE B N   1 
ATOM   6339 C CA  . ILE B 1 254 ? -24.56131 -11.50142 -14.58507 1.000 32.44970  ? 253 ILE B CA  1 
ATOM   6340 C C   . ILE B 1 254 ? -25.01931 -12.21158 -15.84998 1.000 33.94100  ? 253 ILE B C   1 
ATOM   6341 O O   . ILE B 1 254 ? -26.18422 -12.13470 -16.24147 1.000 33.67735  ? 253 ILE B O   1 
ATOM   6342 C CB  . ILE B 1 254 ? -24.06998 -10.09084 -14.91550 1.000 31.65964  ? 253 ILE B CB  1 
ATOM   6343 C CG1 . ILE B 1 254 ? -23.87037 -9.27748  -13.65645 1.000 29.32290  ? 253 ILE B CG1 1 
ATOM   6344 C CG2 . ILE B 1 254 ? -25.05346 -9.39825  -15.81935 1.000 29.43405  ? 253 ILE B CG2 1 
ATOM   6345 C CD1 . ILE B 1 254 ? -23.24500 -7.97366  -13.95451 1.000 29.09503  ? 253 ILE B CD1 1 
ATOM   6346 N N   . TYR B 1 255 ? -24.11584 -12.87248 -16.54927 1.000 36.28764  ? 254 TYR B N   1 
ATOM   6347 C CA  . TYR B 1 255 ? -24.49944 -13.57891 -17.75866 1.000 36.87981  ? 254 TYR B CA  1 
ATOM   6348 C C   . TYR B 1 255 ? -24.69674 -15.06098 -17.48196 1.000 40.84312  ? 254 TYR B C   1 
ATOM   6349 O O   . TYR B 1 255 ? -24.42496 -15.90446 -18.34921 1.000 38.10351  ? 254 TYR B O   1 
ATOM   6350 C CB  . TYR B 1 255 ? -23.45989 -13.33849 -18.85841 1.000 37.25144  ? 254 TYR B CB  1 
ATOM   6351 C CG  . TYR B 1 255 ? -23.51179 -11.95153 -19.49218 1.000 35.76477  ? 254 TYR B CG  1 
ATOM   6352 C CD1 . TYR B 1 255 ? -24.66121 -11.17546 -19.43932 1.000 40.48401  ? 254 TYR B CD1 1 
ATOM   6353 C CD2 . TYR B 1 255 ? -22.41447 -11.42557 -20.15065 1.000 41.40516  ? 254 TYR B CD2 1 
ATOM   6354 C CE1 . TYR B 1 255 ? -24.71440 -9.90749  -20.02968 1.000 43.81844  ? 254 TYR B CE1 1 
ATOM   6355 C CE2 . TYR B 1 255 ? -22.45539 -10.15311 -20.74247 1.000 42.44309  ? 254 TYR B CE2 1 
ATOM   6356 C CZ  . TYR B 1 255 ? -23.60859 -9.40468  -20.67880 1.000 44.16394  ? 254 TYR B CZ  1 
ATOM   6357 O OH  . TYR B 1 255 ? -23.65558 -8.16015  -21.27081 1.000 45.58511  ? 254 TYR B OH  1 
ATOM   6358 N N   . ALA B 1 256 ? -25.15550 -15.38934 -16.26699 1.000 38.19593  ? 255 ALA B N   1 
ATOM   6359 C CA  . ALA B 1 256 ? -25.22075 -16.78726 -15.85805 1.000 33.78047  ? 255 ALA B CA  1 
ATOM   6360 C C   . ALA B 1 256 ? -26.13256 -17.58993 -16.76841 1.000 39.88468  ? 255 ALA B C   1 
ATOM   6361 O O   . ALA B 1 256 ? -25.81297 -18.73800 -17.10298 1.000 43.15209  ? 255 ALA B O   1 
ATOM   6362 C CB  . ALA B 1 256 ? -25.69157 -16.90331 -14.41665 1.000 31.51003  ? 255 ALA B CB  1 
ATOM   6363 N N   . VAL B 1 257 ? -27.27246 -17.00708 -17.18152 1.000 37.89900  ? 256 VAL B N   1 
ATOM   6364 C CA  . VAL B 1 257 ? -28.22858 -17.74565 -18.01181 1.000 36.42925  ? 256 VAL B CA  1 
ATOM   6365 C C   . VAL B 1 257 ? -27.65375 -17.97996 -19.39762 1.000 42.29129  ? 256 VAL B C   1 
ATOM   6366 O O   . VAL B 1 257 ? -27.75798 -19.07730 -19.96291 1.000 39.97182  ? 256 VAL B O   1 
ATOM   6367 C CB  . VAL B 1 257 ? -29.57548 -17.01139 -18.11406 1.000 33.06576  ? 256 VAL B CB  1 
ATOM   6368 C CG1 . VAL B 1 257 ? -30.69280 -17.99081 -17.89933 1.000 39.82984  ? 256 VAL B CG1 1 
ATOM   6369 C CG2 . VAL B 1 257 ? -29.64842 -15.82473 -17.17459 1.000 40.80862  ? 256 VAL B CG2 1 
ATOM   6370 N N   . ASP B 1 258 ? -27.07630 -16.93157 -19.98427 1.000 44.52138  ? 257 ASP B N   1 
ATOM   6371 C CA  . ASP B 1 258 ? -26.46724 -17.08228 -21.29214 1.000 40.24824  ? 257 ASP B CA  1 
ATOM   6372 C C   . ASP B 1 258 ? -25.38158 -18.13496 -21.24563 1.000 36.94427  ? 257 ASP B C   1 
ATOM   6373 O O   . ASP B 1 258 ? -25.25134 -18.93641 -22.17229 1.000 43.92068  ? 257 ASP B O   1 
ATOM   6374 C CB  . ASP B 1 258 ? -25.92699 -15.73966 -21.77659 1.000 43.35391  ? 257 ASP B CB  1 
ATOM   6375 C CG  . ASP B 1 258 ? -27.01075 -14.86970 -22.42292 1.000 52.57893  ? 257 ASP B CG  1 
ATOM   6376 O OD1 . ASP B 1 258 ? -28.16155 -15.36143 -22.57550 1.000 50.02663  ? 257 ASP B OD1 1 
ATOM   6377 O OD2 . ASP B 1 258 ? -26.70523 -13.70380 -22.79027 1.000 47.78267  ? 257 ASP B OD2 1 
ATOM   6378 N N   . ILE B 1 259 ? -24.61777 -18.18188 -20.15750 1.000 34.83832  ? 258 ILE B N   1 
ATOM   6379 C CA  . ILE B 1 259 ? -23.58607 -19.20390 -20.04822 1.000 35.70720  ? 258 ILE B CA  1 
ATOM   6380 C C   . ILE B 1 259 ? -24.21745 -20.58388 -19.96888 1.000 43.13183  ? 258 ILE B C   1 
ATOM   6381 O O   . ILE B 1 259 ? -23.78627 -21.53092 -20.64396 1.000 42.88242  ? 258 ILE B O   1 
ATOM   6382 C CB  . ILE B 1 259 ? -22.69459 -18.95130 -18.83027 1.000 32.37346  ? 258 ILE B CB  1 
ATOM   6383 C CG1 . ILE B 1 259 ? -21.79790 -17.74576 -19.06673 1.000 37.49732  ? 258 ILE B CG1 1 
ATOM   6384 C CG2 . ILE B 1 259 ? -21.87987 -20.18733 -18.57052 1.000 27.53107  ? 258 ILE B CG2 1 
ATOM   6385 C CD1 . ILE B 1 259 ? -21.31945 -17.08530 -17.79964 1.000 33.85496  ? 258 ILE B CD1 1 
ATOM   6386 N N   . ALA B 1 260 ? -25.24728 -20.71650 -19.13220 1.000 42.99314  ? 259 ALA B N   1 
ATOM   6387 C CA  . ALA B 1 260 ? -25.88726 -22.00934 -18.94473 1.000 40.80663  ? 259 ALA B CA  1 
ATOM   6388 C C   . ALA B 1 260 ? -26.49868 -22.51870 -20.24439 1.000 42.03726  ? 259 ALA B C   1 
ATOM   6389 O O   . ALA B 1 260 ? -26.36467 -23.69871 -20.57818 1.000 44.69879  ? 259 ALA B O   1 
ATOM   6390 C CB  . ALA B 1 260 ? -26.94216 -21.90477 -17.84726 1.000 43.17475  ? 259 ALA B CB  1 
ATOM   6391 N N   . GLU B 1 261 ? -27.13384 -21.64023 -21.01172 1.000 42.99446  ? 260 GLU B N   1 
ATOM   6392 C CA  . GLU B 1 261 ? -27.94961 -22.05338 -22.14315 1.000 44.28094  ? 260 GLU B CA  1 
ATOM   6393 C C   . GLU B 1 261 ? -27.18209 -22.14961 -23.47486 1.000 47.20014  ? 260 GLU B C   1 
ATOM   6394 O O   . GLU B 1 261 ? -27.81115 -22.29769 -24.53147 1.000 44.85121  ? 260 GLU B O   1 
ATOM   6395 C CB  . GLU B 1 261 ? -29.13639 -21.10378 -22.27110 1.000 43.58773  ? 260 GLU B CB  1 
ATOM   6396 C CG  . GLU B 1 261 ? -30.20913 -21.38162 -21.24322 1.000 43.16135  ? 260 GLU B CG  1 
ATOM   6397 C CD  . GLU B 1 261 ? -31.31341 -20.34211 -21.27245 1.000 60.05107  ? 260 GLU B CD  1 
ATOM   6398 O OE1 . GLU B 1 261 ? -31.31122 -19.49899 -22.20140 1.000 64.92177  ? 260 GLU B OE1 1 
ATOM   6399 O OE2 . GLU B 1 261 ? -32.18030 -20.36142 -20.36908 1.000 62.13036  ? 260 GLU B OE2 1 
ATOM   6400 N N   . GLY B 1 262 ? -25.84975 -22.09470 -23.45406 1.000 45.33501  ? 261 GLY B N   1 
ATOM   6401 C CA  . GLY B 1 262 ? -25.05814 -22.25718 -24.65534 1.000 38.59575  ? 261 GLY B CA  1 
ATOM   6402 C C   . GLY B 1 262 ? -24.60148 -20.97525 -25.32127 1.000 43.13276  ? 261 GLY B C   1 
ATOM   6403 O O   . GLY B 1 262 ? -23.71039 -21.03068 -26.17670 1.000 45.32015  ? 261 GLY B O   1 
ATOM   6404 N N   . ARG B 1 263 ? -25.16590 -19.82393 -24.95124 1.000 42.44206  ? 262 ARG B N   1 
ATOM   6405 C CA  . ARG B 1 263 ? -24.87109 -18.59357 -25.67535 1.000 39.08770  ? 262 ARG B CA  1 
ATOM   6406 C C   . ARG B 1 263 ? -23.45005 -18.09913 -25.42902 1.000 41.68934  ? 262 ARG B C   1 
ATOM   6407 O O   . ARG B 1 263 ? -22.86543 -17.44221 -26.29337 1.000 45.95863  ? 262 ARG B O   1 
ATOM   6408 C CB  . ARG B 1 263 ? -25.88407 -17.53289 -25.29240 1.000 39.72642  ? 262 ARG B CB  1 
ATOM   6409 C CG  . ARG B 1 263 ? -27.16221 -17.67327 -26.05406 1.000 46.54675  ? 262 ARG B CG  1 
ATOM   6410 C CD  . ARG B 1 263 ? -28.11294 -16.51418 -25.79007 1.000 49.03584  ? 262 ARG B CD  1 
ATOM   6411 N NE  . ARG B 1 263 ? -29.02362 -16.80676 -24.69263 1.000 54.31958  ? 262 ARG B NE  1 
ATOM   6412 C CZ  . ARG B 1 263 ? -29.98069 -17.72399 -24.74296 1.000 63.98676  ? 262 ARG B CZ  1 
ATOM   6413 N NH1 . ARG B 1 263 ? -30.18325 -18.45454 -25.83257 1.000 61.51892  ? 262 ARG B NH1 1 
ATOM   6414 N NH2 . ARG B 1 263 ? -30.75808 -17.90978 -23.67682 1.000 57.92071  ? 262 ARG B NH2 1 
ATOM   6415 N N   . ILE B 1 264 ? -22.88139 -18.38647 -24.27030 1.000 39.60012  ? 263 ILE B N   1 
ATOM   6416 C CA  . ILE B 1 264 ? -21.49545 -18.06555 -23.97880 1.000 37.23143  ? 263 ILE B CA  1 
ATOM   6417 C C   . ILE B 1 264 ? -20.84261 -19.33652 -23.47152 1.000 39.15284  ? 263 ILE B C   1 
ATOM   6418 O O   . ILE B 1 264 ? -21.38022 -19.99051 -22.57416 1.000 41.21785  ? 263 ILE B O   1 
ATOM   6419 C CB  . ILE B 1 264 ? -21.37745 -16.93849 -22.94353 1.000 38.58814  ? 263 ILE B CB  1 
ATOM   6420 C CG1 . ILE B 1 264 ? -21.99861 -15.66435 -23.50291 1.000 37.27771  ? 263 ILE B CG1 1 
ATOM   6421 C CG2 . ILE B 1 264 ? -19.92217 -16.72328 -22.55095 1.000 37.25324  ? 263 ILE B CG2 1 
ATOM   6422 C CD1 . ILE B 1 264 ? -22.14987 -14.56829 -22.46890 1.000 37.38741  ? 263 ILE B CD1 1 
ATOM   6423 N N   . VAL B 1 265 ? -19.71321 -19.70665 -24.06738 1.000 39.35071  ? 264 VAL B N   1 
ATOM   6424 C CA  . VAL B 1 265 ? -19.08096 -20.99899 -23.80209 1.000 36.51812  ? 264 VAL B CA  1 
ATOM   6425 C C   . VAL B 1 265 ? -17.60389 -20.80854 -23.49625 1.000 39.32342  ? 264 VAL B C   1 
ATOM   6426 O O   . VAL B 1 265 ? -16.80946 -20.53927 -24.40600 1.000 41.45721  ? 264 VAL B O   1 
ATOM   6427 C CB  . VAL B 1 265 ? -19.23563 -21.95949 -24.98557 1.000 35.32434  ? 264 VAL B CB  1 
ATOM   6428 C CG1 . VAL B 1 265 ? -18.56642 -23.23036 -24.66588 1.000 32.16663  ? 264 VAL B CG1 1 
ATOM   6429 C CG2 . VAL B 1 265 ? -20.69739 -22.19450 -25.30296 1.000 41.31255  ? 264 VAL B CG2 1 
ATOM   6430 N N   . PRO B 1 266 ? -17.18692 -20.93437 -22.24574 1.000 45.00601  ? 265 PRO B N   1 
ATOM   6431 C CA  . PRO B 1 266 ? -15.75856 -20.82262 -21.95278 1.000 36.41508  ? 265 PRO B CA  1 
ATOM   6432 C C   . PRO B 1 266 ? -15.02629 -21.95741 -22.63641 1.000 33.77056  ? 265 PRO B C   1 
ATOM   6433 O O   . PRO B 1 266 ? -15.55118 -23.06486 -22.74885 1.000 35.50602  ? 265 PRO B O   1 
ATOM   6434 C CB  . PRO B 1 266 ? -15.69875 -20.94418 -20.42591 1.000 31.81468  ? 265 PRO B CB  1 
ATOM   6435 C CG  . PRO B 1 266 ? -17.12738 -20.77964 -19.96030 1.000 29.01932  ? 265 PRO B CG  1 
ATOM   6436 C CD  . PRO B 1 266 ? -17.98894 -21.24939 -21.04778 1.000 35.31187  ? 265 PRO B CD  1 
ATOM   6437 N N   . VAL B 1 267 ? -13.81197 -21.67429 -23.10878 1.000 33.75854  ? 266 VAL B N   1 
ATOM   6438 C CA  . VAL B 1 267 ? -12.96207 -22.69285 -23.71270 1.000 38.93989  ? 266 VAL B CA  1 
ATOM   6439 C C   . VAL B 1 267 ? -11.54924 -22.71630 -23.13967 1.000 40.03351  ? 266 VAL B C   1 
ATOM   6440 O O   . VAL B 1 267 ? -10.71638 -23.48937 -23.61532 1.000 40.77943  ? 266 VAL B O   1 
ATOM   6441 C CB  . VAL B 1 267 ? -12.90556 -22.54450 -25.24985 1.000 36.98237  ? 266 VAL B CB  1 
ATOM   6442 C CG1 . VAL B 1 267 ? -14.29420 -22.53629 -25.83982 1.000 35.25436  ? 266 VAL B CG1 1 
ATOM   6443 C CG2 . VAL B 1 267 ? -12.17273 -21.27992 -25.62378 1.000 39.94582  ? 266 VAL B CG2 1 
ATOM   6444 N N   . GLY B 1 268 ? -11.23381 -21.89987 -22.14585 1.000 36.60856  ? 267 GLY B N   1 
ATOM   6445 C CA  . GLY B 1 268 ? -9.93061  -21.96000 -21.51685 1.000 35.34103  ? 267 GLY B CA  1 
ATOM   6446 C C   . GLY B 1 268 ? -9.05941  -20.76845 -21.87416 1.000 38.00963  ? 267 GLY B C   1 
ATOM   6447 O O   . GLY B 1 268 ? -9.38297  -19.94665 -22.73062 1.000 44.82314  ? 267 GLY B O   1 
ATOM   6448 N N   . ALA B 1 269 ? -7.93322  -20.68629 -21.18284 1.000 34.73086  ? 268 ALA B N   1 
ATOM   6449 C CA  . ALA B 1 269 ? -7.03570  -19.55982 -21.36300 1.000 37.81498  ? 268 ALA B CA  1 
ATOM   6450 C C   . ALA B 1 269 ? -6.30370  -19.65943 -22.68912 1.000 37.22343  ? 268 ALA B C   1 
ATOM   6451 O O   . ALA B 1 269 ? -6.08023  -20.74952 -23.21684 1.000 42.28727  ? 268 ALA B O   1 
ATOM   6452 C CB  . ALA B 1 269 ? -6.01970  -19.50479 -20.22895 1.000 38.48820  ? 268 ALA B CB  1 
ATOM   6453 N N   . GLY B 1 270 ? -5.90761  -18.50648 -23.21772 1.000 35.65601  ? 269 GLY B N   1 
ATOM   6454 C CA  . GLY B 1 270 ? -5.06469  -18.47225 -24.39128 1.000 40.39731  ? 269 GLY B CA  1 
ATOM   6455 C C   . GLY B 1 270 ? -3.65334  -18.99570 -24.14973 1.000 43.55766  ? 269 GLY B C   1 
ATOM   6456 O O   . GLY B 1 270 ? -3.20846  -19.17967 -23.01135 1.000 42.03566  ? 269 GLY B O   1 
ATOM   6457 N N   . PRO B 1 271 ? -2.91270  -19.24940 -25.22985 1.000 43.24688  ? 270 PRO B N   1 
ATOM   6458 C CA  . PRO B 1 271 ? -1.56343  -19.80019 -25.07803 1.000 38.92702  ? 270 PRO B CA  1 
ATOM   6459 C C   . PRO B 1 271 ? -0.49500  -18.77055 -24.75646 1.000 40.64889  ? 270 PRO B C   1 
ATOM   6460 O O   . PRO B 1 271 ? 0.67461   -19.14734 -24.62169 1.000 50.43183  ? 270 PRO B O   1 
ATOM   6461 C CB  . PRO B 1 271 ? -1.31079  -20.45222 -26.44249 1.000 39.00179  ? 270 PRO B CB  1 
ATOM   6462 C CG  . PRO B 1 271 ? -2.14247  -19.66453 -27.38953 1.000 39.58006  ? 270 PRO B CG  1 
ATOM   6463 C CD  . PRO B 1 271 ? -3.34193  -19.18515 -26.64092 1.000 39.25499  ? 270 PRO B CD  1 
ATOM   6464 N N   . ASP B 1 272 ? -0.83955  -17.49429 -24.63633 1.000 36.94211  ? 271 ASP B N   1 
ATOM   6465 C CA  . ASP B 1 272 ? 0.12770   -16.45682 -24.30502 1.000 38.78932  ? 271 ASP B CA  1 
ATOM   6466 C C   . ASP B 1 272 ? -0.23222  -15.80276 -22.97737 1.000 41.03336  ? 271 ASP B C   1 
ATOM   6467 O O   . ASP B 1 272 ? -1.38236  -15.84396 -22.51939 1.000 39.02874  ? 271 ASP B O   1 
ATOM   6468 C CB  . ASP B 1 272 ? 0.20669   -15.35130 -25.38008 1.000 42.78640  ? 271 ASP B CB  1 
ATOM   6469 C CG  . ASP B 1 272 ? 0.34869   -15.89702 -26.80378 1.000 51.66791  ? 271 ASP B CG  1 
ATOM   6470 O OD1 . ASP B 1 272 ? 1.11583   -16.87425 -27.02156 1.000 51.43912  ? 271 ASP B OD1 1 
ATOM   6471 O OD2 . ASP B 1 272 ? -0.31125  -15.32448 -27.70772 1.000 47.68790  ? 271 ASP B OD2 1 
ATOM   6472 N N   . ARG B 1 273 ? 0.76891   -15.17259 -22.37480 1.000 38.60940  ? 272 ARG B N   1 
ATOM   6473 C CA  . ARG B 1 273 ? 0.57773   -14.34551 -21.19827 1.000 35.32519  ? 272 ARG B CA  1 
ATOM   6474 C C   . ARG B 1 273 ? 0.77036   -12.88121 -21.56791 1.000 39.57185  ? 272 ARG B C   1 
ATOM   6475 O O   . ARG B 1 273 ? 1.58272   -12.54080 -22.43563 1.000 38.64883  ? 272 ARG B O   1 
ATOM   6476 C CB  . ARG B 1 273 ? 1.55729   -14.72377 -20.09640 1.000 40.12182  ? 272 ARG B CB  1 
ATOM   6477 C CG  . ARG B 1 273 ? 1.39461   -16.11083 -19.51993 1.000 35.46465  ? 272 ARG B CG  1 
ATOM   6478 C CD  . ARG B 1 273 ? 2.26085   -16.19026 -18.29786 1.000 34.38249  ? 272 ARG B CD  1 
ATOM   6479 N NE  . ARG B 1 273 ? 2.84841   -17.49728 -18.03123 1.000 36.90589  ? 272 ARG B NE  1 
ATOM   6480 C CZ  . ARG B 1 273 ? 4.13902   -17.78731 -18.13712 1.000 37.40858  ? 272 ARG B CZ  1 
ATOM   6481 N NH1 . ARG B 1 273 ? 5.01264   -16.91588 -18.61509 1.000 38.52686  ? 272 ARG B NH1 1 
ATOM   6482 N NH2 . ARG B 1 273 ? 4.56678   -18.97960 -17.73971 1.000 39.84941  ? 272 ARG B NH2 1 
ATOM   6483 N N   . TYR B 1 274 ? 0.02228   -12.01807 -20.88423 1.000 41.27770  ? 273 TYR B N   1 
ATOM   6484 C CA  . TYR B 1 274 ? -0.02425  -10.58807 -21.15806 1.000 41.64061  ? 273 TYR B CA  1 
ATOM   6485 C C   . TYR B 1 274 ? 0.42229   -9.77900  -19.94270 1.000 40.35908  ? 273 TYR B C   1 
ATOM   6486 O O   . TYR B 1 274 ? 0.25647   -10.20903 -18.80181 1.000 41.81265  ? 273 TYR B O   1 
ATOM   6487 C CB  . TYR B 1 274 ? -1.43808  -10.16108 -21.52620 1.000 40.02553  ? 273 TYR B CB  1 
ATOM   6488 C CG  . TYR B 1 274 ? -1.92267  -10.67880 -22.84259 1.000 39.50927  ? 273 TYR B CG  1 
ATOM   6489 C CD1 . TYR B 1 274 ? -2.44792  -11.95413 -22.94902 1.000 35.09264  ? 273 TYR B CD1 1 
ATOM   6490 C CD2 . TYR B 1 274 ? -1.87734  -9.88057  -23.98547 1.000 41.89367  ? 273 TYR B CD2 1 
ATOM   6491 C CE1 . TYR B 1 274 ? -2.89927  -12.43377 -24.16360 1.000 42.47375  ? 273 TYR B CE1 1 
ATOM   6492 C CE2 . TYR B 1 274 ? -2.33950  -10.35314 -25.20960 1.000 41.62473  ? 273 TYR B CE2 1 
ATOM   6493 C CZ  . TYR B 1 274 ? -2.85088  -11.63006 -25.28570 1.000 40.65171  ? 273 TYR B CZ  1 
ATOM   6494 O OH  . TYR B 1 274 ? -3.30473  -12.11342 -26.47992 1.000 43.85310  ? 273 TYR B OH  1 
ATOM   6495 N N   . GLN B 1 275 ? 0.94909   -8.57858  -20.18608 1.000 37.56544  ? 274 GLN B N   1 
ATOM   6496 C CA  . GLN B 1 275 ? 1.30401   -7.67832  -19.09915 1.000 39.07490  ? 274 GLN B CA  1 
ATOM   6497 C C   . GLN B 1 275 ? 0.42076   -6.44668  -19.15243 1.000 37.83042  ? 274 GLN B C   1 
ATOM   6498 O O   . GLN B 1 275 ? 0.38965   -5.76186  -20.18407 1.000 37.32103  ? 274 GLN B O   1 
ATOM   6499 C CB  . GLN B 1 275 ? 2.77365   -7.27384  -19.17464 1.000 42.33840  ? 274 GLN B CB  1 
ATOM   6500 C CG  . GLN B 1 275 ? 3.21810   -6.29614  -18.08020 1.000 37.51770  ? 274 GLN B CG  1 
ATOM   6501 C CD  . GLN B 1 275 ? 4.73856   -6.18908  -18.00351 1.000 37.59601  ? 274 GLN B CD  1 
ATOM   6502 O OE1 . GLN B 1 275 ? 5.44029   -7.18986  -18.15286 1.000 37.38820  ? 274 GLN B OE1 1 
ATOM   6503 N NE2 . GLN B 1 275 ? 5.25090   -4.97972  -17.76803 1.000 33.48586  ? 274 GLN B NE2 1 
ATOM   6504 N N   . PRO B 1 276 ? -0.28220  -6.11657  -18.07132 1.000 41.15901  ? 275 PRO B N   1 
ATOM   6505 C CA  . PRO B 1 276 ? -1.13838  -4.92224  -18.07485 1.000 36.46318  ? 275 PRO B CA  1 
ATOM   6506 C C   . PRO B 1 276 ? -0.32065  -3.65538  -18.25560 1.000 35.07857  ? 275 PRO B C   1 
ATOM   6507 O O   . PRO B 1 276 ? 0.65221   -3.42199  -17.53942 1.000 41.76518  ? 275 PRO B O   1 
ATOM   6508 C CB  . PRO B 1 276 ? -1.79414  -4.96330  -16.69293 1.000 34.64223  ? 275 PRO B CB  1 
ATOM   6509 C CG  . PRO B 1 276 ? -0.84770  -5.72992  -15.86818 1.000 31.56793  ? 275 PRO B CG  1 
ATOM   6510 C CD  . PRO B 1 276 ? -0.25975  -6.77524  -16.75679 1.000 32.13859  ? 275 PRO B CD  1 
ATOM   6511 N N   . GLN B 1 277 ? -0.73052  -2.82604  -19.20518 1.000 35.28652  ? 276 GLN B N   1 
ATOM   6512 C CA  . GLN B 1 277 ? -0.12840  -1.50755  -19.36255 1.000 39.42838  ? 276 GLN B CA  1 
ATOM   6513 C C   . GLN B 1 277 ? -0.74882  -0.54566  -18.34746 1.000 36.17463  ? 276 GLN B C   1 
ATOM   6514 O O   . GLN B 1 277 ? -1.58349  -0.92239  -17.52481 1.000 39.51565  ? 276 GLN B O   1 
ATOM   6515 C CB  . GLN B 1 277 ? -0.30629  -0.99302  -20.79118 1.000 38.67725  ? 276 GLN B CB  1 
ATOM   6516 C CG  . GLN B 1 277 ? 0.06514   -1.95651  -21.86563 1.000 32.31193  ? 276 GLN B CG  1 
ATOM   6517 C CD  . GLN B 1 277 ? 1.53666   -2.21538  -21.88918 1.000 37.83251  ? 276 GLN B CD  1 
ATOM   6518 O OE1 . GLN B 1 277 ? 2.03264   -3.08620  -21.16933 1.000 37.45725  ? 276 GLN B OE1 1 
ATOM   6519 N NE2 . GLN B 1 277 ? 2.25987   -1.45778  -22.71471 1.000 37.87498  ? 276 GLN B NE2 1 
ATOM   6520 N N   . GLN B 1 278 ? -0.38904  0.73317   -18.43860 1.000 38.29224  ? 277 GLN B N   1 
ATOM   6521 C CA  . GLN B 1 278 ? -0.86421  1.71105   -17.46805 1.000 37.42845  ? 277 GLN B CA  1 
ATOM   6522 C C   . GLN B 1 278 ? -2.38008  1.85635   -17.46116 1.000 38.30461  ? 277 GLN B C   1 
ATOM   6523 O O   . GLN B 1 278 ? -2.95542  2.08835   -16.40076 1.000 46.67387  ? 277 GLN B O   1 
ATOM   6524 C CB  . GLN B 1 278 ? -0.17592  3.05196   -17.70839 1.000 36.08132  ? 277 GLN B CB  1 
ATOM   6525 C CG  . GLN B 1 278 ? 1.28136   2.95539   -17.31451 1.000 35.95699  ? 277 GLN B CG  1 
ATOM   6526 C CD  . GLN B 1 278 ? 2.09721   4.13159   -17.70549 1.000 39.78120  ? 277 GLN B CD  1 
ATOM   6527 O OE1 . GLN B 1 278 ? 2.62192   4.18619   -18.81238 1.000 45.87704  ? 277 GLN B OE1 1 
ATOM   6528 N NE2 . GLN B 1 278 ? 2.24871   5.07783   -16.78846 1.000 44.92589  ? 277 GLN B NE2 1 
ATOM   6529 N N   . SER B 1 279 ? -3.05426  1.68985   -18.59812 1.000 42.70127  ? 278 SER B N   1 
ATOM   6530 C CA  . SER B 1 279 ? -4.52114  1.72144   -18.59760 1.000 43.83458  ? 278 SER B CA  1 
ATOM   6531 C C   . SER B 1 279 ? -5.16058  0.62439   -17.73373 1.000 40.92998  ? 278 SER B C   1 
ATOM   6532 O O   . SER B 1 279 ? -6.35928  0.72398   -17.43773 1.000 40.77927  ? 278 SER B O   1 
ATOM   6533 C CB  . SER B 1 279 ? -5.06360  1.59631   -20.02570 1.000 49.83134  ? 278 SER B CB  1 
ATOM   6534 O OG  . SER B 1 279 ? -4.13118  2.07989   -20.97385 1.000 61.23752  ? 278 SER B OG  1 
ATOM   6535 N N   . ILE B 1 280 ? -4.39548  -0.41128  -17.34570 1.000 37.74910  ? 279 ILE B N   1 
ATOM   6536 C CA  . ILE B 1 280 ? -4.80882  -1.56718  -16.53861 1.000 32.77995  ? 279 ILE B CA  1 
ATOM   6537 C C   . ILE B 1 280 ? -5.59812  -2.56057  -17.38118 1.000 35.30407  ? 279 ILE B C   1 
ATOM   6538 O O   . ILE B 1 280 ? -5.37511  -3.77623  -17.29792 1.000 40.37263  ? 279 ILE B O   1 
ATOM   6539 C CB  . ILE B 1 280 ? -5.62814  -1.17622  -15.28822 1.000 34.49947  ? 279 ILE B CB  1 
ATOM   6540 C CG1 . ILE B 1 280 ? -4.94550  -0.07364  -14.47689 1.000 36.03375  ? 279 ILE B CG1 1 
ATOM   6541 C CG2 . ILE B 1 280 ? -5.87730  -2.39140  -14.40780 1.000 28.59954  ? 279 ILE B CG2 1 
ATOM   6542 C CD1 . ILE B 1 280 ? -5.92821  0.77021   -13.70928 1.000 39.60476  ? 279 ILE B CD1 1 
ATOM   6543 N N   . ARG B 1 281 ? -6.54385  -2.06080  -18.17341 1.000 34.26091  ? 280 ARG B N   1 
ATOM   6544 C CA  . ARG B 1 281 ? -7.42779  -2.90163  -18.97439 1.000 35.26240  ? 280 ARG B CA  1 
ATOM   6545 C C   . ARG B 1 281 ? -6.90664  -3.12990  -20.38584 1.000 39.27609  ? 280 ARG B C   1 
ATOM   6546 O O   . ARG B 1 281 ? -7.59054  -3.76990  -21.19187 1.000 36.70948  ? 280 ARG B O   1 
ATOM   6547 C CB  . ARG B 1 281 ? -8.81456  -2.27728  -19.05057 1.000 32.78718  ? 280 ARG B CB  1 
ATOM   6548 C CG  . ARG B 1 281 ? -8.79938  -0.96346  -19.78535 1.000 32.47408  ? 280 ARG B CG  1 
ATOM   6549 C CD  . ARG B 1 281 ? -10.17811 -0.44254  -20.00611 1.000 32.44465  ? 280 ARG B CD  1 
ATOM   6550 N NE  . ARG B 1 281 ? -10.10941 0.83512   -20.68830 1.000 39.47386  ? 280 ARG B NE  1 
ATOM   6551 C CZ  . ARG B 1 281 ? -11.16690 1.50816   -21.10123 1.000 41.06646  ? 280 ARG B CZ  1 
ATOM   6552 N NH1 . ARG B 1 281 ? -12.39256 1.07080   -20.86909 1.000 38.41127  ? 280 ARG B NH1 1 
ATOM   6553 N NH2 . ARG B 1 281 ? -10.98926 2.63321   -21.78547 1.000 44.41209  ? 280 ARG B NH2 1 
ATOM   6554 N N   . THR B 1 282 ? -5.73163  -2.60356  -20.70793 1.000 36.15774  ? 281 THR B N   1 
ATOM   6555 C CA  . THR B 1 282 ? -5.07593  -2.85946  -21.97620 1.000 35.60817  ? 281 THR B CA  1 
ATOM   6556 C C   . THR B 1 282 ? -3.78281  -3.58544  -21.66779 1.000 39.47068  ? 281 THR B C   1 
ATOM   6557 O O   . THR B 1 282 ? -2.91393  -3.03261  -20.98341 1.000 40.04257  ? 281 THR B O   1 
ATOM   6558 C CB  . THR B 1 282 ? -4.79504  -1.56162  -22.72232 1.000 41.29086  ? 281 THR B CB  1 
ATOM   6559 O OG1 . THR B 1 282 ? -6.00896  -0.80944  -22.86204 1.000 44.15675  ? 281 THR B OG1 1 
ATOM   6560 C CG2 . THR B 1 282 ? -4.22490  -1.86835  -24.06949 1.000 38.64083  ? 281 THR B CG2 1 
ATOM   6561 N N   . VAL B 1 283 ? -3.66236  -4.81976  -22.15835 1.000 38.51260  ? 282 VAL B N   1 
ATOM   6562 C CA  . VAL B 1 283 ? -2.52842  -5.68368  -21.84830 1.000 36.40301  ? 282 VAL B CA  1 
ATOM   6563 C C   . VAL B 1 283 ? -1.68572  -5.92690  -23.10014 1.000 34.37787  ? 282 VAL B C   1 
ATOM   6564 O O   . VAL B 1 283 ? -2.18027  -5.90025  -24.23298 1.000 37.91575  ? 282 VAL B O   1 
ATOM   6565 C CB  . VAL B 1 283 ? -3.00710  -7.00677  -21.21237 1.000 33.67053  ? 282 VAL B CB  1 
ATOM   6566 C CG1 . VAL B 1 283 ? -3.70676  -6.71375  -19.92302 1.000 34.25119  ? 282 VAL B CG1 1 
ATOM   6567 C CG2 . VAL B 1 283 ? -3.93696  -7.75827  -22.14582 1.000 33.38849  ? 282 VAL B CG2 1 
ATOM   6568 N N   . PHE B 1 284 ? -0.39565  -6.15381  -22.87939 1.000 30.93391  ? 283 PHE B N   1 
ATOM   6569 C CA  . PHE B 1 284 ? 0.59886   -6.31921  -23.92521 1.000 31.25928  ? 283 PHE B CA  1 
ATOM   6570 C C   . PHE B 1 284 ? 1.05341   -7.77147  -23.94378 1.000 35.77489  ? 283 PHE B C   1 
ATOM   6571 O O   . PHE B 1 284 ? 1.31793   -8.35379  -22.89141 1.000 38.13877  ? 283 PHE B O   1 
ATOM   6572 C CB  . PHE B 1 284 ? 1.78113   -5.37530  -23.66768 1.000 34.85022  ? 283 PHE B CB  1 
ATOM   6573 C CG  . PHE B 1 284 ? 2.91915   -5.51762  -24.64281 1.000 40.61761  ? 283 PHE B CG  1 
ATOM   6574 C CD1 . PHE B 1 284 ? 2.94614   -4.76901  -25.81759 1.000 41.78553  ? 283 PHE B CD1 1 
ATOM   6575 C CD2 . PHE B 1 284 ? 3.97855   -6.38262  -24.37783 1.000 38.79752  ? 283 PHE B CD2 1 
ATOM   6576 C CE1 . PHE B 1 284 ? 3.99790   -4.89207  -26.72136 1.000 40.68870  ? 283 PHE B CE1 1 
ATOM   6577 C CE2 . PHE B 1 284 ? 5.02805   -6.51340  -25.27779 1.000 40.62593  ? 283 PHE B CE2 1 
ATOM   6578 C CZ  . PHE B 1 284 ? 5.03961   -5.76275  -26.45191 1.000 40.06701  ? 283 PHE B CZ  1 
ATOM   6579 N N   . ASN B 1 285 ? 1.14976   -8.36070  -25.13359 1.000 37.67979  ? 284 ASN B N   1 
ATOM   6580 C CA  . ASN B 1 285 ? 1.45552   -9.78813  -25.25208 1.000 36.38858  ? 284 ASN B CA  1 
ATOM   6581 C C   . ASN B 1 285 ? 2.93324   -10.02238 -24.97693 1.000 39.26061  ? 284 ASN B C   1 
ATOM   6582 O O   . ASN B 1 285 ? 3.76191   -9.88409  -25.87280 1.000 38.33237  ? 284 ASN B O   1 
ATOM   6583 C CB  . ASN B 1 285 ? 1.08891   -10.29244 -26.63830 1.000 38.67734  ? 284 ASN B CB  1 
ATOM   6584 C CG  . ASN B 1 285 ? 1.11067   -11.80100 -26.73635 1.000 41.41630  ? 284 ASN B CG  1 
ATOM   6585 O OD1 . ASN B 1 285 ? 1.96929   -12.45761 -26.15258 1.000 41.41321  ? 284 ASN B OD1 1 
ATOM   6586 N ND2 . ASN B 1 285 ? 0.15995   -12.36146 -27.48163 1.000 43.48971  ? 284 ASN B ND2 1 
ATOM   6587 N N   . VAL B 1 286 ? 3.28308   -10.41729 -23.74559 1.000 42.87982  ? 285 VAL B N   1 
ATOM   6588 C CA  . VAL B 1 286 ? 4.70307   -10.61876 -23.44175 1.000 39.54843  ? 285 VAL B CA  1 
ATOM   6589 C C   . VAL B 1 286 ? 5.23600   -11.97055 -23.88090 1.000 37.66461  ? 285 VAL B C   1 
ATOM   6590 O O   . VAL B 1 286 ? 6.45663   -12.14913 -23.90912 1.000 39.90916  ? 285 VAL B O   1 
ATOM   6591 C CB  . VAL B 1 286 ? 5.04599   -10.46942 -21.95032 1.000 35.74509  ? 285 VAL B CB  1 
ATOM   6592 C CG1 . VAL B 1 286 ? 5.10132   -8.99394  -21.57052 1.000 34.91032  ? 285 VAL B CG1 1 
ATOM   6593 C CG2 . VAL B 1 286 ? 4.05052   -11.23021 -21.10281 1.000 39.39802  ? 285 VAL B CG2 1 
ATOM   6594 N N   . SER B 1 287 ? 4.37084   -12.92504 -24.22841 1.000 38.41854  ? 286 SER B N   1 
ATOM   6595 C CA  . SER B 1 287 ? 4.84983   -14.17451 -24.81451 1.000 36.06190  ? 286 SER B CA  1 
ATOM   6596 C C   . SER B 1 287 ? 5.28682   -13.95958 -26.25828 1.000 45.02924  ? 286 SER B C   1 
ATOM   6597 O O   . SER B 1 287 ? 6.38134   -14.37214 -26.66095 1.000 46.74051  ? 286 SER B O   1 
ATOM   6598 C CB  . SER B 1 287 ? 3.75546   -15.23878 -24.75152 1.000 40.79520  ? 286 SER B CB  1 
ATOM   6599 O OG  . SER B 1 287 ? 3.12027   -15.25551 -23.48102 1.000 47.91384  ? 286 SER B OG  1 
ATOM   6600 N N   . VAL B 1 288 ? 4.43424   -13.31410 -27.04851 1.000 44.26441  ? 287 VAL B N   1 
ATOM   6601 C CA  . VAL B 1 288 ? 4.65597   -13.04362 -28.46493 1.000 38.71995  ? 287 VAL B CA  1 
ATOM   6602 C C   . VAL B 1 288 ? 4.51954   -11.54029 -28.66743 1.000 39.58294  ? 287 VAL B C   1 
ATOM   6603 O O   . VAL B 1 288 ? 3.42219   -11.05488 -28.99075 1.000 40.86578  ? 287 VAL B O   1 
ATOM   6604 C CB  . VAL B 1 288 ? 3.64975   -13.80492 -29.33998 1.000 40.07104  ? 287 VAL B CB  1 
ATOM   6605 C CG1 . VAL B 1 288 ? 3.83953   -13.45309 -30.78807 1.000 39.30070  ? 287 VAL B CG1 1 
ATOM   6606 C CG2 . VAL B 1 288 ? 3.79240   -15.27563 -29.14447 1.000 40.88317  ? 287 VAL B CG2 1 
ATOM   6607 N N   . PRO B 1 289 ? 5.59221   -10.76844 -28.48927 1.000 38.28598  ? 288 PRO B N   1 
ATOM   6608 C CA  . PRO B 1 289 ? 5.44440   -9.29585  -28.45114 1.000 40.26961  ? 288 PRO B CA  1 
ATOM   6609 C C   . PRO B 1 289 ? 4.91801   -8.66074  -29.74565 1.000 37.66102  ? 288 PRO B C   1 
ATOM   6610 O O   . PRO B 1 289 ? 4.46474   -7.50829  -29.69412 1.000 35.51151  ? 288 PRO B O   1 
ATOM   6611 C CB  . PRO B 1 289 ? 6.86200   -8.79632  -28.11507 1.000 39.29166  ? 288 PRO B CB  1 
ATOM   6612 C CG  . PRO B 1 289 ? 7.63283   -10.00806 -27.66295 1.000 34.41557  ? 288 PRO B CG  1 
ATOM   6613 C CD  . PRO B 1 289 ? 6.97158   -11.22208 -28.23837 1.000 32.84699  ? 288 PRO B CD  1 
ATOM   6614 N N   . THR B 1 290 ? 4.95755   -9.35394  -30.89198 1.000 33.85432  ? 289 THR B N   1 
ATOM   6615 C CA  . THR B 1 290 ? 4.37242   -8.79740  -32.10523 1.000 34.13110  ? 289 THR B CA  1 
ATOM   6616 C C   . THR B 1 290 ? 2.89956   -9.11189  -32.24432 1.000 36.13721  ? 289 THR B C   1 
ATOM   6617 O O   . THR B 1 290 ? 2.25830   -8.56407  -33.14253 1.000 44.26359  ? 289 THR B O   1 
ATOM   6618 C CB  . THR B 1 290 ? 5.07931   -9.29021  -33.36608 1.000 29.96657  ? 289 THR B CB  1 
ATOM   6619 O OG1 . THR B 1 290 ? 5.07651   -10.71381 -33.37250 1.000 38.25606  ? 289 THR B OG1 1 
ATOM   6620 C CG2 . THR B 1 290 ? 6.49153   -8.78862  -33.43582 1.000 33.78055  ? 289 THR B CG2 1 
ATOM   6621 N N   . ARG B 1 291 ? 2.35029   -9.97018  -31.39267 1.000 37.13086  ? 290 ARG B N   1 
ATOM   6622 C CA  . ARG B 1 291 ? 0.91539   -10.18484 -31.39002 1.000 34.74729  ? 290 ARG B CA  1 
ATOM   6623 C C   . ARG B 1 291 ? 0.20387   -8.96421  -30.81533 1.000 37.39972  ? 290 ARG B C   1 
ATOM   6624 O O   . ARG B 1 291 ? 0.81150   -8.09612  -30.19216 1.000 44.23204  ? 290 ARG B O   1 
ATOM   6625 C CB  . ARG B 1 291 ? 0.57839   -11.44373 -30.61041 1.000 37.06780  ? 290 ARG B CB  1 
ATOM   6626 C CG  . ARG B 1 291 ? 0.32435   -12.60454 -31.52995 1.000 38.98283  ? 290 ARG B CG  1 
ATOM   6627 C CD  . ARG B 1 291 ? 0.29429   -13.91309 -30.81492 1.000 44.18042  ? 290 ARG B CD  1 
ATOM   6628 N NE  . ARG B 1 291 ? -0.12501  -15.00557 -31.68251 1.000 43.86411  ? 290 ARG B NE  1 
ATOM   6629 C CZ  . ARG B 1 291 ? 0.08568   -16.28663 -31.41059 1.000 48.11084  ? 290 ARG B CZ  1 
ATOM   6630 N NH1 . ARG B 1 291 ? 0.75802   -16.66292 -30.32767 1.000 47.45919  ? 290 ARG B NH1 1 
ATOM   6631 N NH2 . ARG B 1 291 ? -0.40105  -17.21378 -32.23371 1.000 43.10255  ? 290 ARG B NH2 1 
ATOM   6632 N N   . HIS B 1 292 ? -1.09529  -8.88622  -31.05202 1.000 35.07290  ? 291 HIS B N   1 
ATOM   6633 C CA  . HIS B 1 292 ? -1.82450  -7.67707  -30.70798 1.000 33.88278  ? 291 HIS B CA  1 
ATOM   6634 C C   . HIS B 1 292 ? -1.88468  -7.45831  -29.19999 1.000 37.44265  ? 291 HIS B C   1 
ATOM   6635 O O   . HIS B 1 292 ? -1.91069  -8.41328  -28.41255 1.000 37.54794  ? 291 HIS B O   1 
ATOM   6636 C CB  . HIS B 1 292 ? -3.24845  -7.75178  -31.25275 1.000 39.90936  ? 291 HIS B CB  1 
ATOM   6637 C CG  . HIS B 1 292 ? -3.33998  -7.57773  -32.73790 1.000 44.44257  ? 291 HIS B CG  1 
ATOM   6638 N ND1 . HIS B 1 292 ? -3.45258  -8.64344  -33.60674 1.000 42.37102  ? 291 HIS B ND1 1 
ATOM   6639 C CD2 . HIS B 1 292 ? -3.33675  -6.46181  -33.50631 1.000 38.76639  ? 291 HIS B CD2 1 
ATOM   6640 C CE1 . HIS B 1 292 ? -3.51211  -8.18890  -34.84474 1.000 42.05880  ? 291 HIS B CE1 1 
ATOM   6641 N NE2 . HIS B 1 292 ? -3.44087  -6.87009  -34.81107 1.000 37.62394  ? 291 HIS B NE2 1 
ATOM   6642 N N   . TYR B 1 293 ? -1.88079  -6.17307  -28.81064 1.000 36.04843  ? 292 TYR B N   1 
ATOM   6643 C CA  . TYR B 1 293 ? -2.50409  -5.73388  -27.56382 1.000 34.58874  ? 292 TYR B CA  1 
ATOM   6644 C C   . TYR B 1 293 ? -3.92560  -6.26293  -27.50053 1.000 36.65036  ? 292 TYR B C   1 
ATOM   6645 O O   . TYR B 1 293 ? -4.61445  -6.36291  -28.51778 1.000 35.75884  ? 292 TYR B O   1 
ATOM   6646 C CB  . TYR B 1 293 ? -2.60950  -4.20152  -27.47361 1.000 31.83513  ? 292 TYR B CB  1 
ATOM   6647 C CG  . TYR B 1 293 ? -1.36074  -3.40675  -27.18703 1.000 38.44283  ? 292 TYR B CG  1 
ATOM   6648 C CD1 . TYR B 1 293 ? -0.83326  -3.32457  -25.90872 1.000 35.24759  ? 292 TYR B CD1 1 
ATOM   6649 C CD2 . TYR B 1 293 ? -0.73558  -2.68331  -28.19595 1.000 41.69199  ? 292 TYR B CD2 1 
ATOM   6650 C CE1 . TYR B 1 293 ? 0.31046   -2.57382  -25.65609 1.000 36.84429  ? 292 TYR B CE1 1 
ATOM   6651 C CE2 . TYR B 1 293 ? 0.40000   -1.93348  -27.95277 1.000 38.28842  ? 292 TYR B CE2 1 
ATOM   6652 C CZ  . TYR B 1 293 ? 0.92082   -1.88091  -26.68778 1.000 40.42598  ? 292 TYR B CZ  1 
ATOM   6653 O OH  . TYR B 1 293 ? 2.05178   -1.12046  -26.46281 1.000 44.55859  ? 292 TYR B OH  1 
ATOM   6654 N N   . VAL B 1 294 ? -4.40403  -6.54875  -26.30075 1.000 33.88050  ? 293 VAL B N   1 
ATOM   6655 C CA  . VAL B 1 294 ? -5.83314  -6.73074  -26.09589 1.000 35.73916  ? 293 VAL B CA  1 
ATOM   6656 C C   . VAL B 1 294 ? -6.28787  -5.65794  -25.12217 1.000 38.34400  ? 293 VAL B C   1 
ATOM   6657 O O   . VAL B 1 294 ? -5.61569  -5.40762  -24.11455 1.000 42.53253  ? 293 VAL B O   1 
ATOM   6658 C CB  . VAL B 1 294 ? -6.18054  -8.13672  -25.57573 1.000 39.30911  ? 293 VAL B CB  1 
ATOM   6659 C CG1 . VAL B 1 294 ? -7.70118  -8.29114  -25.48052 1.000 35.17510  ? 293 VAL B CG1 1 
ATOM   6660 C CG2 . VAL B 1 294 ? -5.54804  -9.22543  -26.46050 1.000 30.48204  ? 293 VAL B CG2 1 
ATOM   6661 N N   . LYS B 1 295 ? -7.38943  -4.98954  -25.44443 1.000 33.55109  ? 294 LYS B N   1 
ATOM   6662 C CA  . LYS B 1 295 ? -8.03724  -4.07806  -24.51607 1.000 34.02910  ? 294 LYS B CA  1 
ATOM   6663 C C   . LYS B 1 295 ? -9.38487  -4.69087  -24.19134 1.000 34.85712  ? 294 LYS B C   1 
ATOM   6664 O O   . LYS B 1 295 ? -10.19518 -4.93114  -25.09221 1.000 38.66964  ? 294 LYS B O   1 
ATOM   6665 C CB  . LYS B 1 295 ? -8.18081  -2.66699  -25.08548 1.000 37.30553  ? 294 LYS B CB  1 
ATOM   6666 C CG  . LYS B 1 295 ? -9.15686  -1.77373  -24.31332 1.000 37.22763  ? 294 LYS B CG  1 
ATOM   6667 C CD  . LYS B 1 295 ? -9.31106  -0.44112  -25.01665 1.000 41.68102  ? 294 LYS B CD  1 
ATOM   6668 C CE  . LYS B 1 295 ? -9.91463  0.62541   -24.12746 1.000 41.45554  ? 294 LYS B CE  1 
ATOM   6669 N NZ  . LYS B 1 295 ? -10.07857 1.91922   -24.86476 1.000 42.91758  ? 294 LYS B NZ  1 
ATOM   6670 N N   . THR B 1 296 ? -9.59222  -4.97180  -22.91393 1.000 33.41719  ? 295 THR B N   1 
ATOM   6671 C CA  . THR B 1 296 ? -10.68699 -5.76868  -22.39952 1.000 29.03714  ? 295 THR B CA  1 
ATOM   6672 C C   . THR B 1 296 ? -11.58577 -4.88668  -21.56082 1.000 33.39276  ? 295 THR B C   1 
ATOM   6673 O O   . THR B 1 296 ? -11.10860 -3.98647  -20.87339 1.000 42.16211  ? 295 THR B O   1 
ATOM   6674 C CB  . THR B 1 296 ? -10.16185 -6.87664  -21.49752 1.000 38.06793  ? 295 THR B CB  1 
ATOM   6675 O OG1 . THR B 1 296 ? -9.39512  -6.27091  -20.43967 1.000 38.46082  ? 295 THR B OG1 1 
ATOM   6676 C CG2 . THR B 1 296 ? -9.29392  -7.86144  -22.25964 1.000 31.51128  ? 295 THR B CG2 1 
ATOM   6677 N N   . ALA B 1 297 ? -12.87905 -5.17133  -21.57462 1.000 37.17073  ? 296 ALA B N   1 
ATOM   6678 C CA  . ALA B 1 297 ? -13.76725 -4.54438  -20.60457 1.000 37.63480  ? 296 ALA B CA  1 
ATOM   6679 C C   . ALA B 1 297 ? -13.34545 -4.93911  -19.19350 1.000 38.08197  ? 296 ALA B C   1 
ATOM   6680 O O   . ALA B 1 297 ? -13.26475 -6.12707  -18.87347 1.000 40.28732  ? 296 ALA B O   1 
ATOM   6681 C CB  . ALA B 1 297 ? -15.20845 -4.95624  -20.86969 1.000 33.11700  ? 296 ALA B CB  1 
ATOM   6682 N N   . LEU B 1 298 ? -13.03307 -3.94460  -18.36422 1.000 34.91718  ? 297 LEU B N   1 
ATOM   6683 C CA  . LEU B 1 298 ? -12.65053 -4.15736  -16.96891 1.000 31.52844  ? 297 LEU B CA  1 
ATOM   6684 C C   . LEU B 1 298 ? -13.50409 -3.20222  -16.14616 1.000 40.54143  ? 297 LEU B C   1 
ATOM   6685 O O   . LEU B 1 298 ? -13.12867 -2.05539  -15.88212 1.000 39.78394  ? 297 LEU B O   1 
ATOM   6686 C CB  . LEU B 1 298 ? -11.18470 -3.91194  -16.74033 1.000 32.86780  ? 297 LEU B CB  1 
ATOM   6687 C CG  . LEU B 1 298 ? -10.60169 -4.52658  -15.46912 1.000 36.26463  ? 297 LEU B CG  1 
ATOM   6688 C CD1 . LEU B 1 298 ? -10.65440 -6.04276  -15.51476 1.000 33.06973  ? 297 LEU B CD1 1 
ATOM   6689 C CD2 . LEU B 1 298 ? -9.18368  -4.05836  -15.26746 1.000 32.76550  ? 297 LEU B CD2 1 
ATOM   6690 N N   . SER B 1 299 ? -14.66336 -3.67772  -15.72738 1.000 36.79379  ? 298 SER B N   1 
ATOM   6691 C CA  . SER B 1 299 ? -15.57959 -2.82068  -15.00173 1.000 37.05101  ? 298 SER B CA  1 
ATOM   6692 C C   . SER B 1 299 ? -15.08615 -2.45219  -13.60468 1.000 39.67327  ? 298 SER B C   1 
ATOM   6693 O O   . SER B 1 299 ? -15.77932 -2.72439  -12.62719 1.000 39.93001  ? 298 SER B O   1 
ATOM   6694 C CB  . SER B 1 299 ? -16.92864 -3.51678  -14.91897 1.000 36.63406  ? 298 SER B CB  1 
ATOM   6695 O OG  . SER B 1 299 ? -17.37903 -3.83338  -16.22232 1.000 36.06071  ? 298 SER B OG  1 
ATOM   6696 N N   . ILE B 1 300 ? -13.89934 -1.85108  -13.48378 1.000 40.43696  ? 299 ILE B N   1 
ATOM   6697 C CA  . ILE B 1 300 ? -13.47826 -1.25166  -12.21954 1.000 41.00325  ? 299 ILE B CA  1 
ATOM   6698 C C   . ILE B 1 300 ? -13.77033 0.23979   -12.32049 1.000 48.60923  ? 299 ILE B C   1 
ATOM   6699 O O   . ILE B 1 300 ? -14.28150 0.70357   -13.34633 1.000 51.59213  ? 299 ILE B O   1 
ATOM   6700 C CB  . ILE B 1 300 ? -11.99206 -1.51479  -11.91280 1.000 37.98800  ? 299 ILE B CB  1 
ATOM   6701 C CG1 . ILE B 1 300 ? -11.13175 -1.30047  -13.14447 1.000 35.14491  ? 299 ILE B CG1 1 
ATOM   6702 C CG2 . ILE B 1 300 ? -11.79087 -2.91758  -11.43241 1.000 37.27308  ? 299 ILE B CG2 1 
ATOM   6703 C CD1 . ILE B 1 300 ? -9.69053  -1.07580  -12.79793 1.000 37.16854  ? 299 ILE B CD1 1 
ATOM   6704 N N   . VAL B 1 301 ? -13.46115 1.01095   -11.27838 1.000 45.52443  ? 300 VAL B N   1 
ATOM   6705 C CA  . VAL B 1 301 ? -13.57790 2.46514   -11.34434 1.000 46.33023  ? 300 VAL B CA  1 
ATOM   6706 C C   . VAL B 1 301 ? -12.20733 3.08402   -11.11921 1.000 50.44974  ? 300 VAL B C   1 
ATOM   6707 O O   . VAL B 1 301 ? -11.53895 2.77110   -10.12637 1.000 47.02631  ? 300 VAL B O   1 
ATOM   6708 C CB  . VAL B 1 301 ? -14.58750 3.00985   -10.32793 1.000 44.43684  ? 300 VAL B CB  1 
ATOM   6709 C CG1 . VAL B 1 301 ? -14.57581 4.51627   -10.37945 1.000 49.80775  ? 300 VAL B CG1 1 
ATOM   6710 C CG2 . VAL B 1 301 ? -15.94591 2.48474   -10.65303 1.000 45.29037  ? 300 VAL B CG2 1 
ATOM   6711 N N   . ASN B 1 302 ? -11.79326 3.96117   -12.03910 1.000 51.78348  ? 301 ASN B N   1 
ATOM   6712 C CA  . ASN B 1 302 ? -10.46423 4.56625   -11.98278 1.000 49.12103  ? 301 ASN B CA  1 
ATOM   6713 C C   . ASN B 1 302 ? -10.54956 5.95528   -12.59042 1.000 57.79231  ? 301 ASN B C   1 
ATOM   6714 O O   . ASN B 1 302 ? -10.76826 6.08590   -13.79572 1.000 70.50014  ? 301 ASN B O   1 
ATOM   6715 C CB  . ASN B 1 302 ? -9.43548  3.71807   -12.71564 1.000 45.79688  ? 301 ASN B CB  1 
ATOM   6716 C CG  . ASN B 1 302 ? -8.07381  3.79177   -12.07262 1.000 52.13802  ? 301 ASN B CG  1 
ATOM   6717 O OD1 . ASN B 1 302 ? -7.96729  3.83167   -10.84263 1.000 49.46089  ? 301 ASN B OD1 1 
ATOM   6718 N ND2 . ASN B 1 302 ? -7.01769  3.82326   -12.89175 1.000 53.05826  ? 301 ASN B ND2 1 
ATOM   6719 N N   . MET B 1 303 ? -10.37531 6.98021   -11.75303 1.000 68.35304  ? 302 MET B N   1 
ATOM   6720 C CA  . MET B 1 303 ? -10.48438 8.39409   -12.14431 1.000 64.44014  ? 302 MET B CA  1 
ATOM   6721 C C   . MET B 1 303 ? -11.94596 8.76984   -12.40653 1.000 67.67012  ? 302 MET B C   1 
ATOM   6722 O O   . MET B 1 303 ? -12.29240 9.32199   -13.45306 1.000 68.61713  ? 302 MET B O   1 
ATOM   6723 C CB  . MET B 1 303 ? -9.56986  8.70920   -13.33493 1.000 43.91064  ? 302 MET B CB  1 
ATOM   6724 C CG  . MET B 1 303 ? -8.10700  8.55901   -12.88242 1.000 56.98915  ? 302 MET B CG  1 
ATOM   6725 S SD  . MET B 1 303 ? -6.70096  8.94491   -13.94781 1.000 56.35748  ? 302 MET B SD  1 
ATOM   6726 C CE  . MET B 1 303 ? -6.28816  7.31763   -14.59652 1.000 44.27817  ? 302 MET B CE  1 
ATOM   6727 N N   . GLY B 1 304 ? -12.80784 8.44940   -11.42637 1.000 64.91979  ? 303 GLY B N   1 
ATOM   6728 C CA  . GLY B 1 304 ? -14.23755 8.72454   -11.46306 1.000 68.28261  ? 303 GLY B CA  1 
ATOM   6729 C C   . GLY B 1 304 ? -14.97908 7.92814   -12.51899 1.000 75.16639  ? 303 GLY B C   1 
ATOM   6730 O O   . GLY B 1 304 ? -16.21376 7.78844   -12.47553 1.000 66.01050  ? 303 GLY B O   1 
ATOM   6731 N N   . PHE B 1 305 ? -14.18595 7.37147   -13.44571 1.000 77.08281  ? 304 PHE B N   1 
ATOM   6732 C CA  . PHE B 1 305 ? -14.61427 6.71833   -14.67837 1.000 70.01780  ? 304 PHE B CA  1 
ATOM   6733 C C   . PHE B 1 305 ? -14.63426 5.19824   -14.53416 1.000 60.52141  ? 304 PHE B C   1 
ATOM   6734 O O   . PHE B 1 305 ? -13.69422 4.58764   -14.01379 1.000 59.64428  ? 304 PHE B O   1 
ATOM   6735 C CB  . PHE B 1 305 ? -13.66817 7.08093   -15.82483 1.000 72.28937  ? 304 PHE B CB  1 
ATOM   6736 C CG  . PHE B 1 305 ? -14.07256 8.30181   -16.58704 1.000 83.15232  ? 304 PHE B CG  1 
ATOM   6737 C CD1 . PHE B 1 305 ? -15.32813 8.86604   -16.40434 1.000 81.36625  ? 304 PHE B CD1 1 
ATOM   6738 C CD2 . PHE B 1 305 ? -13.19484 8.88185   -17.50372 1.000 78.93533  ? 304 PHE B CD2 1 
ATOM   6739 C CE1 . PHE B 1 305 ? -15.70079 9.99190   -17.11696 1.000 84.85121  ? 304 PHE B CE1 1 
ATOM   6740 C CE2 . PHE B 1 305 ? -13.55693 10.00923  -18.21807 1.000 78.76138  ? 304 PHE B CE2 1 
ATOM   6741 C CZ  . PHE B 1 305 ? -14.81144 10.56735  -18.02726 1.000 85.03223  ? 304 PHE B CZ  1 
ATOM   6742 N N   . THR B 1 306 ? -15.68118 4.59013   -15.04970 1.000 49.67134  ? 305 THR B N   1 
ATOM   6743 C CA  . THR B 1 306 ? -15.87738 3.16170   -14.94035 1.000 46.04223  ? 305 THR B CA  1 
ATOM   6744 C C   . THR B 1 306 ? -15.42756 2.50601   -16.24458 1.000 48.15144  ? 305 THR B C   1 
ATOM   6745 O O   . THR B 1 306 ? -15.95453 2.81416   -17.31675 1.000 52.45787  ? 305 THR B O   1 
ATOM   6746 C CB  . THR B 1 306 ? -17.34293 2.89161   -14.61374 1.000 51.20681  ? 305 THR B CB  1 
ATOM   6747 O OG1 . THR B 1 306 ? -17.63443 1.50429   -14.78914 1.000 55.65831  ? 305 THR B OG1 1 
ATOM   6748 C CG2 . THR B 1 306 ? -18.26420 3.77425   -15.48203 1.000 47.75321  ? 305 THR B CG2 1 
ATOM   6749 N N   . ARG B 1 307 ? -14.46538 1.58729   -16.14836 1.000 47.07708  ? 306 ARG B N   1 
ATOM   6750 C CA  . ARG B 1 307 ? -13.64022 1.19148   -17.28289 1.000 42.11744  ? 306 ARG B CA  1 
ATOM   6751 C C   . ARG B 1 307 ? -14.17465 -0.01567  -18.05596 1.000 37.90127  ? 306 ARG B C   1 
ATOM   6752 O O   . ARG B 1 307 ? -13.39053 -0.79078  -18.61700 1.000 36.06321  ? 306 ARG B O   1 
ATOM   6753 C CB  . ARG B 1 307 ? -12.21201 0.94457   -16.80396 1.000 42.04565  ? 306 ARG B CB  1 
ATOM   6754 C CG  . ARG B 1 307 ? -11.57113 2.19008   -16.21678 1.000 47.86675  ? 306 ARG B CG  1 
ATOM   6755 C CD  . ARG B 1 307 ? -10.03117 2.12709   -16.23986 1.000 56.28255  ? 306 ARG B CD  1 
ATOM   6756 N NE  . ARG B 1 307 ? -9.44658  2.68735   -17.45805 1.000 61.65238  ? 306 ARG B NE  1 
ATOM   6757 C CZ  . ARG B 1 307 ? -9.71888  3.89022   -17.96157 1.000 75.80021  ? 306 ARG B CZ  1 
ATOM   6758 N NH1 . ARG B 1 307 ? -10.48125 4.76824   -17.31047 1.000 72.48765  ? 306 ARG B NH1 1 
ATOM   6759 N NH2 . ARG B 1 307 ? -9.19791  4.23179   -19.14286 1.000 66.15180  ? 306 ARG B NH2 1 
ATOM   6760 N N   . GLY B 1 308 ? -15.48386 -0.18060  -18.15013 1.000 45.33627  ? 307 GLY B N   1 
ATOM   6761 C CA  . GLY B 1 308 ? -16.03510 -1.11133  -19.11064 1.000 41.33852  ? 307 GLY B CA  1 
ATOM   6762 C C   . GLY B 1 308 ? -16.07102 -0.50017  -20.50066 1.000 40.74843  ? 307 GLY B C   1 
ATOM   6763 O O   . GLY B 1 308 ? -15.68913 0.64781   -20.72699 1.000 45.39369  ? 307 GLY B O   1 
ATOM   6764 N N   . MET B 1 309 ? -16.56117 -1.28726  -21.45098 1.000 39.51814  ? 308 MET B N   1 
ATOM   6765 C CA  . MET B 1 309 ? -16.60371 -0.88115  -22.85314 1.000 39.21394  ? 308 MET B CA  1 
ATOM   6766 C C   . MET B 1 309 ? -17.91426 -1.35049  -23.46181 1.000 40.67921  ? 308 MET B C   1 
ATOM   6767 O O   . MET B 1 309 ? -18.19962 -2.55227  -23.44717 1.000 36.40061  ? 308 MET B O   1 
ATOM   6768 C CB  . MET B 1 309 ? -15.42987 -1.47749  -23.63126 1.000 38.13514  ? 308 MET B CB  1 
ATOM   6769 C CG  . MET B 1 309 ? -14.17613 -0.65011  -23.61677 1.000 38.40097  ? 308 MET B CG  1 
ATOM   6770 S SD  . MET B 1 309 ? -12.84045 -1.40540  -24.57075 1.000 53.20247  ? 308 MET B SD  1 
ATOM   6771 C CE  . MET B 1 309 ? -13.30021 -3.13798  -24.58033 1.000 42.01401  ? 308 MET B CE  1 
ATOM   6772 N N   . SER B 1 310 ? -18.70197 -0.42964  -24.01958 1.000 41.77211  ? 309 SER B N   1 
ATOM   6773 C CA  . SER B 1 310 ? -19.98776 -0.83446  -24.58231 1.000 45.46161  ? 309 SER B CA  1 
ATOM   6774 C C   . SER B 1 310 ? -19.79504 -1.55234  -25.91601 1.000 44.53775  ? 309 SER B C   1 
ATOM   6775 O O   . SER B 1 310 ? -18.89377 -1.22648  -26.69216 1.000 40.03776  ? 309 SER B O   1 
ATOM   6776 C CB  . SER B 1 310 ? -20.92728 0.36421   -24.74411 1.000 41.63110  ? 309 SER B CB  1 
ATOM   6777 O OG  . SER B 1 310 ? -20.41222 1.32035   -25.63356 1.000 47.19030  ? 309 SER B OG  1 
ATOM   6778 N N   . ALA B 1 311 ? -20.63015 -2.56674  -26.15895 1.000 46.77863  ? 310 ALA B N   1 
ATOM   6779 C CA  . ALA B 1 311 ? -20.58137 -3.28330  -27.42873 1.000 48.71295  ? 310 ALA B CA  1 
ATOM   6780 C C   . ALA B 1 311 ? -21.09326 -2.43130  -28.57679 1.000 54.98881  ? 310 ALA B C   1 
ATOM   6781 O O   . ALA B 1 311 ? -20.86552 -2.76452  -29.74755 1.000 56.01620  ? 310 ALA B O   1 
ATOM   6782 C CB  . ALA B 1 311 ? -21.39818 -4.57282  -27.35199 1.000 49.55894  ? 310 ALA B CB  1 
ATOM   6783 N N   . ASP B 1 312 ? -21.78537 -1.34212  -28.26444 1.000 54.74482  ? 311 ASP B N   1 
ATOM   6784 C CA  . ASP B 1 312 ? -22.18894 -0.41002  -29.30010 1.000 55.43135  ? 311 ASP B CA  1 
ATOM   6785 C C   . ASP B 1 312 ? -20.99671 0.41807   -29.78880 1.000 60.25624  ? 311 ASP B C   1 
ATOM   6786 O O   . ASP B 1 312 ? -20.90523 0.73726   -30.98257 1.000 57.51019  ? 311 ASP B O   1 
ATOM   6787 C CB  . ASP B 1 312 ? -23.34619 0.41987   -28.74711 1.000 63.08866  ? 311 ASP B CB  1 
ATOM   6788 C CG  . ASP B 1 312 ? -24.40893 -0.47141  -28.01715 1.000 77.23137  ? 311 ASP B CG  1 
ATOM   6789 O OD1 . ASP B 1 312 ? -24.98745 -1.36438  -28.69584 1.000 75.33336  ? 311 ASP B OD1 1 
ATOM   6790 O OD2 . ASP B 1 312 ? -24.66275 -0.29158  -26.78377 1.000 66.56347  ? 311 ASP B OD2 1 
ATOM   6791 N N   . TYR B 1 313 ? -20.03850 0.71067   -28.90144 1.000 59.59047  ? 312 TYR B N   1 
ATOM   6792 C CA  . TYR B 1 313 ? -18.76413 1.28519   -29.33741 1.000 54.51683  ? 312 TYR B CA  1 
ATOM   6793 C C   . TYR B 1 313 ? -17.93110 0.28873   -30.14194 1.000 50.44797  ? 312 TYR B C   1 
ATOM   6794 O O   . TYR B 1 313 ? -17.33357 0.65799   -31.15829 1.000 55.92238  ? 312 TYR B O   1 
ATOM   6795 C CB  . TYR B 1 313 ? -17.96739 1.78864   -28.13303 1.000 48.79641  ? 312 TYR B CB  1 
ATOM   6796 C CG  . TYR B 1 313 ? -18.29752 3.21351   -27.79788 1.000 62.45924  ? 312 TYR B CG  1 
ATOM   6797 C CD1 . TYR B 1 313 ? -19.57492 3.71675   -28.03625 1.000 64.06767  ? 312 TYR B CD1 1 
ATOM   6798 C CD2 . TYR B 1 313 ? -17.32201 4.08487   -27.31164 1.000 66.64694  ? 312 TYR B CD2 1 
ATOM   6799 C CE1 . TYR B 1 313 ? -19.89292 5.03439   -27.76055 1.000 68.54278  ? 312 TYR B CE1 1 
ATOM   6800 C CE2 . TYR B 1 313 ? -17.62812 5.41804   -27.03264 1.000 66.93960  ? 312 TYR B CE2 1 
ATOM   6801 C CZ  . TYR B 1 313 ? -18.91868 5.88503   -27.26054 1.000 73.70882  ? 312 TYR B CZ  1 
ATOM   6802 O OH  . TYR B 1 313 ? -19.24798 7.20066   -26.99656 1.000 75.51210  ? 312 TYR B OH  1 
ATOM   6803 N N   . MET B 1 314 ? -17.84801 -0.96525  -29.68638 1.000 47.61598  ? 313 MET B N   1 
ATOM   6804 C CA  . MET B 1 314 ? -17.08694 -1.97654  -30.40926 1.000 42.90691  ? 313 MET B CA  1 
ATOM   6805 C C   . MET B 1 314 ? -17.51655 -2.02757  -31.86283 1.000 51.30527  ? 313 MET B C   1 
ATOM   6806 O O   . MET B 1 314 ? -16.69072 -2.20751  -32.76433 1.000 48.74895  ? 313 MET B O   1 
ATOM   6807 C CB  . MET B 1 314 ? -17.27813 -3.34397  -29.75254 1.000 38.95683  ? 313 MET B CB  1 
ATOM   6808 C CG  . MET B 1 314 ? -16.66335 -3.47905  -28.35690 1.000 40.26661  ? 313 MET B CG  1 
ATOM   6809 S SD  . MET B 1 314 ? -15.03886 -2.69862  -28.15454 1.000 38.51106  ? 313 MET B SD  1 
ATOM   6810 C CE  . MET B 1 314 ? -15.47597 -1.24700  -27.22347 1.000 43.46834  ? 313 MET B CE  1 
ATOM   6811 N N   . ARG B 1 315 ? -18.81222 -1.84097  -32.11008 1.000 55.76937  ? 314 ARG B N   1 
ATOM   6812 C CA  . ARG B 1 315 ? -19.32684 -1.91081  -33.47029 1.000 46.65315  ? 314 ARG B CA  1 
ATOM   6813 C C   . ARG B 1 315 ? -18.64554 -0.89713  -34.36587 1.000 46.94638  ? 314 ARG B C   1 
ATOM   6814 O O   . ARG B 1 315 ? -18.35735 -1.18206  -35.53225 1.000 57.35557  ? 314 ARG B O   1 
ATOM   6815 C CB  . ARG B 1 315 ? -20.82927 -1.67162  -33.45425 1.000 52.42656  ? 314 ARG B CB  1 
ATOM   6816 C CG  . ARG B 1 315 ? -21.61919 -2.52495  -34.39421 1.000 53.17692  ? 314 ARG B CG  1 
ATOM   6817 C CD  . ARG B 1 315 ? -23.04958 -2.02115  -34.44465 1.000 58.64861  ? 314 ARG B CD  1 
ATOM   6818 N NE  . ARG B 1 315 ? -23.70675 -2.07730  -33.14248 1.000 66.60794  ? 314 ARG B NE  1 
ATOM   6819 C CZ  . ARG B 1 315 ? -24.03888 -1.01277  -32.42274 1.000 70.45697  ? 314 ARG B CZ  1 
ATOM   6820 N NH1 . ARG B 1 315 ? -23.75063 0.21409   -32.83185 1.000 73.27232  ? 314 ARG B NH1 1 
ATOM   6821 N NH2 . ARG B 1 315 ? -24.67409 -1.18300  -31.26386 1.000 63.65069  ? 314 ARG B NH2 1 
ATOM   6822 N N   . THR B 1 316 ? -18.35810 0.28440   -33.83114 1.000 47.06074  ? 315 THR B N   1 
ATOM   6823 C CA  . THR B 1 316 ? -18.01081 1.43960   -34.63922 1.000 46.86587  ? 315 THR B CA  1 
ATOM   6824 C C   . THR B 1 316 ? -16.58608 1.94135   -34.44436 1.000 51.13335  ? 315 THR B C   1 
ATOM   6825 O O   . THR B 1 316 ? -16.16355 2.83626   -35.18381 1.000 50.65026  ? 315 THR B O   1 
ATOM   6826 C CB  . THR B 1 316 ? -18.97842 2.58497   -34.33295 1.000 47.06644  ? 315 THR B CB  1 
ATOM   6827 O OG1 . THR B 1 316 ? -18.46385 3.35169   -33.24024 1.000 57.10804  ? 315 THR B OG1 1 
ATOM   6828 C CG2 . THR B 1 316 ? -20.31279 2.02882   -33.92897 1.000 52.78654  ? 315 THR B CG2 1 
ATOM   6829 N N   . THR B 1 317 ? -15.84122 1.41796   -33.47471 1.000 49.82064  ? 316 THR B N   1 
ATOM   6830 C CA  . THR B 1 317 ? -14.47556 1.89449   -33.28019 1.000 46.54356  ? 316 THR B CA  1 
ATOM   6831 C C   . THR B 1 317 ? -13.51517 1.48920   -34.40445 1.000 44.00586  ? 316 THR B C   1 
ATOM   6832 O O   . THR B 1 317 ? -12.72324 2.33209   -34.84228 1.000 44.94222  ? 316 THR B O   1 
ATOM   6833 C CB  . THR B 1 317 ? -13.93344 1.42813   -31.93073 1.000 41.04990  ? 316 THR B CB  1 
ATOM   6834 O OG1 . THR B 1 317 ? -14.54794 2.20707   -30.89766 1.000 57.58471  ? 316 THR B OG1 1 
ATOM   6835 C CG2 . THR B 1 317 ? -12.42189 1.63360   -31.86042 1.000 33.10521  ? 316 THR B CG2 1 
ATOM   6836 N N   . PRO B 1 318 ? -13.51163 0.24725   -34.90726 1.000 39.82470  ? 317 PRO B N   1 
ATOM   6837 C CA  . PRO B 1 318 ? -12.56222 -0.07099  -35.97998 1.000 45.88934  ? 317 PRO B CA  1 
ATOM   6838 C C   . PRO B 1 318 ? -12.90194 0.63683   -37.28298 1.000 49.41279  ? 317 PRO B C   1 
ATOM   6839 O O   . PRO B 1 318 ? -12.05017 0.70735   -38.18349 1.000 44.82135  ? 317 PRO B O   1 
ATOM   6840 C CB  . PRO B 1 318 ? -12.66975 -1.60551  -36.11873 1.000 41.24923  ? 317 PRO B CB  1 
ATOM   6841 C CG  . PRO B 1 318 ? -13.45091 -2.05740  -34.99399 1.000 40.15413  ? 317 PRO B CG  1 
ATOM   6842 C CD  . PRO B 1 318 ? -14.35980 -0.91852  -34.63552 1.000 45.91804  ? 317 PRO B CD  1 
ATOM   6843 N N   . LEU B 1 319 ? -14.11654 1.17833   -37.38641 1.000 49.00940  ? 318 LEU B N   1 
ATOM   6844 C CA  . LEU B 1 319 ? -14.53233 1.93400   -38.55849 1.000 43.65974  ? 318 LEU B CA  1 
ATOM   6845 C C   . LEU B 1 319 ? -13.95591 3.35049   -38.53322 1.000 46.97020  ? 318 LEU B C   1 
ATOM   6846 O O   . LEU B 1 319 ? -13.27741 3.77032   -39.47734 1.000 53.28394  ? 318 LEU B O   1 
ATOM   6847 C CB  . LEU B 1 319 ? -16.05791 1.94300   -38.63660 1.000 41.36677  ? 318 LEU B CB  1 
ATOM   6848 C CG  . LEU B 1 319 ? -16.64410 0.74083   -39.38547 1.000 38.99425  ? 318 LEU B CG  1 
ATOM   6849 C CD1 . LEU B 1 319 ? -16.03705 -0.57939  -38.93184 1.000 43.26364  ? 318 LEU B CD1 1 
ATOM   6850 C CD2 . LEU B 1 319 ? -18.14493 0.70082   -39.24631 1.000 40.67305  ? 318 LEU B CD2 1 
ATOM   6851 N N   . ILE B 1 320 ? -14.20781 4.09839   -37.45445 1.000 44.00723  ? 319 ILE B N   1 
ATOM   6852 C CA  . ILE B 1 320 ? -13.52143 5.37244   -37.24220 1.000 43.21449  ? 319 ILE B CA  1 
ATOM   6853 C C   . ILE B 1 320 ? -12.01837 5.22157   -37.44607 1.000 46.78602  ? 319 ILE B C   1 
ATOM   6854 O O   . ILE B 1 320 ? -11.36479 6.09112   -38.03218 1.000 48.27013  ? 319 ILE B O   1 
ATOM   6855 C CB  . ILE B 1 320 ? -13.84150 5.91790   -35.84178 1.000 41.23139  ? 319 ILE B CB  1 
ATOM   6856 C CG1 . ILE B 1 320 ? -15.29337 6.36994   -35.78262 1.000 49.19467  ? 319 ILE B CG1 1 
ATOM   6857 C CG2 . ILE B 1 320 ? -12.92191 7.06265   -35.49170 1.000 42.14322  ? 319 ILE B CG2 1 
ATOM   6858 C CD1 . ILE B 1 320 ? -15.75415 6.71891   -34.40526 1.000 55.28022  ? 319 ILE B CD1 1 
ATOM   6859 N N   . ASN B 1 321 ? -11.44365 4.12207   -36.96079 1.000 44.96163  ? 320 ASN B N   1 
ATOM   6860 C CA  . ASN B 1 321 ? -10.03086 3.86420   -37.20859 1.000 45.27813  ? 320 ASN B CA  1 
ATOM   6861 C C   . ASN B 1 321 ? -9.74264  3.80099   -38.70478 1.000 50.66856  ? 320 ASN B C   1 
ATOM   6862 O O   . ASN B 1 321 ? -8.73700  4.34714   -39.17787 1.000 50.07293  ? 320 ASN B O   1 
ATOM   6863 C CB  . ASN B 1 321 ? -9.61349  2.54920   -36.54919 1.000 52.59268  ? 320 ASN B CB  1 
ATOM   6864 C CG  . ASN B 1 321 ? -9.18094  2.70455   -35.09578 1.000 47.51915  ? 320 ASN B CG  1 
ATOM   6865 O OD1 . ASN B 1 321 ? -8.07685  2.30615   -34.72398 1.000 47.42947  ? 320 ASN B OD1 1 
ATOM   6866 N ND2 . ASN B 1 321 ? -10.06490 3.22845   -34.26424 1.000 49.45501  ? 320 ASN B ND2 1 
ATOM   6867 N N   . ASP B 1 322 ? -10.60517 3.11240   -39.46388 1.000 53.28328  ? 321 ASP B N   1 
ATOM   6868 C CA  . ASP B 1 322 ? -10.37431 2.94963   -40.89688 1.000 47.51732  ? 321 ASP B CA  1 
ATOM   6869 C C   . ASP B 1 322 ? -10.37542 4.29969   -41.59771 1.000 51.12517  ? 321 ASP B C   1 
ATOM   6870 O O   . ASP B 1 322 ? -9.51142  4.58290   -42.43862 1.000 51.65481  ? 321 ASP B O   1 
ATOM   6871 C CB  . ASP B 1 322 ? -11.43864 2.03136   -41.49332 1.000 45.03207  ? 321 ASP B CB  1 
ATOM   6872 C CG  . ASP B 1 322 ? -10.84975 0.95756   -42.39657 1.000 56.83329  ? 321 ASP B CG  1 
ATOM   6873 O OD1 . ASP B 1 322 ? -9.60470  0.81362   -42.44500 1.000 55.68791  ? 321 ASP B OD1 1 
ATOM   6874 O OD2 . ASP B 1 322 ? -11.64170 0.26228   -43.07464 1.000 59.60821  ? 321 ASP B OD2 1 
ATOM   6875 N N   . TRP B 1 323 ? -11.32970 5.15269   -41.23735 1.000 47.95412  ? 322 TRP B N   1 
ATOM   6876 C CA  . TRP B 1 323 ? -11.37676 6.50618   -41.76502 1.000 47.91159  ? 322 TRP B CA  1 
ATOM   6877 C C   . TRP B 1 323 ? -10.09661 7.28733   -41.45354 1.000 50.65358  ? 322 TRP B C   1 
ATOM   6878 O O   . TRP B 1 323 ? -9.51021  7.91125   -42.34224 1.000 57.02539  ? 322 TRP B O   1 
ATOM   6879 C CB  . TRP B 1 323 ? -12.60471 7.20710   -41.20287 1.000 54.35884  ? 322 TRP B CB  1 
ATOM   6880 C CG  . TRP B 1 323 ? -12.90002 8.44722   -41.90557 1.000 62.01610  ? 322 TRP B CG  1 
ATOM   6881 C CD1 . TRP B 1 323 ? -13.49429 8.58647   -43.13100 1.000 63.77686  ? 322 TRP B CD1 1 
ATOM   6882 C CD2 . TRP B 1 323 ? -12.60236 9.75215   -41.44779 1.000 58.29580  ? 322 TRP B CD2 1 
ATOM   6883 N NE1 . TRP B 1 323 ? -13.58479 9.91302   -43.45441 1.000 68.34412  ? 322 TRP B NE1 1 
ATOM   6884 C CE2 . TRP B 1 323 ? -13.03879 10.64979  -42.43379 1.000 63.76368  ? 322 TRP B CE2 1 
ATOM   6885 C CE3 . TRP B 1 323 ? -11.99859 10.25178  -40.29879 1.000 60.50769  ? 322 TRP B CE3 1 
ATOM   6886 C CZ2 . TRP B 1 323 ? -12.90131 12.02135  -42.29567 1.000 63.78243  ? 322 TRP B CZ2 1 
ATOM   6887 C CZ3 . TRP B 1 323 ? -11.86386 11.60659  -40.16317 1.000 61.61281  ? 322 TRP B CZ3 1 
ATOM   6888 C CH2 . TRP B 1 323 ? -12.31083 12.47946  -41.15497 1.000 64.65217  ? 322 TRP B CH2 1 
ATOM   6889 N N   . VAL B 1 324 ? -9.64088  7.26529   -40.19989 1.000 51.25726  ? 323 VAL B N   1 
ATOM   6890 C CA  . VAL B 1 324 ? -8.42330  7.99672   -39.84025 1.000 49.02555  ? 323 VAL B CA  1 
ATOM   6891 C C   . VAL B 1 324 ? -7.23695  7.50416   -40.66455 1.000 49.47013  ? 323 VAL B C   1 
ATOM   6892 O O   . VAL B 1 324 ? -6.58252  8.28654   -41.36129 1.000 49.20807  ? 323 VAL B O   1 
ATOM   6893 C CB  . VAL B 1 324 ? -8.14379  7.89495   -38.32968 1.000 39.35687  ? 323 VAL B CB  1 
ATOM   6894 C CG1 . VAL B 1 324 ? -6.70404  8.21835   -38.03754 1.000 42.50791  ? 323 VAL B CG1 1 
ATOM   6895 C CG2 . VAL B 1 324 ? -9.01850  8.85175   -37.57548 1.000 35.14339  ? 323 VAL B CG2 1 
ATOM   6896 N N   . ARG B 1 325 ? -6.94217  6.20048   -40.60693 1.000 48.09524  ? 324 ARG B N   1 
ATOM   6897 C CA  . ARG B 1 325 ? -5.80692  5.69593   -41.37600 1.000 52.52722  ? 324 ARG B CA  1 
ATOM   6898 C C   . ARG B 1 325 ? -5.90113  6.09188   -42.85038 1.000 54.52485  ? 324 ARG B C   1 
ATOM   6899 O O   . ARG B 1 325 ? -4.87658  6.37432   -43.48803 1.000 54.31432  ? 324 ARG B O   1 
ATOM   6900 C CB  . ARG B 1 325 ? -5.67625  4.17220   -41.24884 1.000 49.65134  ? 324 ARG B CB  1 
ATOM   6901 C CG  . ARG B 1 325 ? -4.55230  3.59731   -42.13209 1.000 51.55707  ? 324 ARG B CG  1 
ATOM   6902 C CD  . ARG B 1 325 ? -4.33655  2.11139   -41.94487 1.000 56.72827  ? 324 ARG B CD  1 
ATOM   6903 N NE  . ARG B 1 325 ? -5.39228  1.32327   -42.56597 1.000 62.21041  ? 324 ARG B NE  1 
ATOM   6904 C CZ  . ARG B 1 325 ? -5.67842  0.06626   -42.24741 1.000 66.73336  ? 324 ARG B CZ  1 
ATOM   6905 N NH1 . ARG B 1 325 ? -4.99939  -0.58542  -41.31510 1.000 66.38813  ? 324 ARG B NH1 1 
ATOM   6906 N NH2 . ARG B 1 325 ? -6.67719  -0.55158  -42.87453 1.000 65.98320  ? 324 ARG B NH2 1 
ATOM   6907 N N   . SER B 1 326 ? -7.11347  6.15547   -43.40411 1.000 54.20717  ? 325 SER B N   1 
ATOM   6908 C CA  . SER B 1 326 ? -7.23775  6.50909   -44.81787 1.000 62.21021  ? 325 SER B CA  1 
ATOM   6909 C C   . SER B 1 326 ? -6.96229  7.99212   -45.05124 1.000 59.82755  ? 325 SER B C   1 
ATOM   6910 O O   . SER B 1 326 ? -6.35418  8.36256   -46.06117 1.000 57.53071  ? 325 SER B O   1 
ATOM   6911 C CB  . SER B 1 326 ? -8.62364  6.14039   -45.34028 1.000 60.32905  ? 325 SER B CB  1 
ATOM   6912 O OG  . SER B 1 326 ? -9.51514  7.23475   -45.17651 1.000 62.14423  ? 325 SER B OG  1 
ATOM   6913 N N   . ARG B 1 327 ? -7.40501  8.85755   -44.13644 1.000 57.25106  ? 326 ARG B N   1 
ATOM   6914 C CA  . ARG B 1 327 ? -7.15047  10.28226  -44.30177 1.000 53.71663  ? 326 ARG B CA  1 
ATOM   6915 C C   . ARG B 1 327 ? -5.69081  10.65252  -44.04098 1.000 50.93574  ? 326 ARG B C   1 
ATOM   6916 O O   . ARG B 1 327 ? -5.35519  11.83633  -44.12825 1.000 54.73338  ? 326 ARG B O   1 
ATOM   6917 C CB  . ARG B 1 327 ? -8.08772  11.09607  -43.39559 1.000 43.46966  ? 326 ARG B CB  1 
ATOM   6918 N N   . VAL B 1 328 ? -4.82081  9.68841   -43.72475 1.000 49.24308  ? 327 VAL B N   1 
ATOM   6919 C CA  . VAL B 1 328 ? -3.39277  9.93852   -43.56486 1.000 44.61152  ? 327 VAL B CA  1 
ATOM   6920 C C   . VAL B 1 328 ? -2.53474  8.90442   -44.27195 1.000 46.68049  ? 327 VAL B C   1 
ATOM   6921 O O   . VAL B 1 328 ? -1.31224  9.03386   -44.27595 1.000 44.20782  ? 327 VAL B O   1 
ATOM   6922 C CB  . VAL B 1 328 ? -2.98180  10.02670  -42.08088 1.000 46.51135  ? 327 VAL B CB  1 
ATOM   6923 C CG1 . VAL B 1 328 ? -3.82293  11.05044  -41.32879 1.000 48.68299  ? 327 VAL B CG1 1 
ATOM   6924 C CG2 . VAL B 1 328 ? -3.08742  8.66621   -41.42733 1.000 48.60472  ? 327 VAL B CG2 1 
ATOM   6925 N N   . HIS B 1 329 ? -3.13237  7.86562   -44.85323 1.000 57.33659  ? 328 HIS B N   1 
ATOM   6926 C CA  . HIS B 1 329 ? -2.41271  6.94788   -45.73058 1.000 58.59153  ? 328 HIS B CA  1 
ATOM   6927 C C   . HIS B 1 329 ? -1.68896  7.73729   -46.81551 1.000 56.93006  ? 328 HIS B C   1 
ATOM   6928 O O   . HIS B 1 329 ? -2.31792  8.20780   -47.76531 1.000 57.16373  ? 328 HIS B O   1 
ATOM   6929 C CB  . HIS B 1 329 ? -3.38737  5.93043   -46.34450 1.000 58.02824  ? 328 HIS B CB  1 
ATOM   6930 C CG  . HIS B 1 329 ? -2.95465  5.37381   -47.67064 1.000 61.34798  ? 328 HIS B CG  1 
ATOM   6931 N ND1 . HIS B 1 329 ? -1.99048  4.39753   -47.79550 1.000 62.82229  ? 328 HIS B ND1 1 
ATOM   6932 C CD2 . HIS B 1 329 ? -3.36913  5.64823   -48.93050 1.000 67.72866  ? 328 HIS B CD2 1 
ATOM   6933 C CE1 . HIS B 1 329 ? -1.82188  4.10142   -49.07271 1.000 63.35030  ? 328 HIS B CE1 1 
ATOM   6934 N NE2 . HIS B 1 329 ? -2.65042  4.84309   -49.78324 1.000 67.90502  ? 328 HIS B NE2 1 
ATOM   6935 N N   . GLY B 1 330 ? -0.37955  7.93162   -46.66787 1.000 55.39837  ? 329 GLY B N   1 
ATOM   6936 C CA  . GLY B 1 330 ? 0.38083   8.56542   -47.72794 1.000 50.68575  ? 329 GLY B CA  1 
ATOM   6937 C C   . GLY B 1 330 ? 1.14463   9.79711   -47.29624 1.000 56.32319  ? 329 GLY B C   1 
ATOM   6938 O O   . GLY B 1 330 ? 2.30998   9.96105   -47.67150 1.000 60.31681  ? 329 GLY B O   1 
ATOM   6939 N N   . ASP B 1 331 ? 0.49028   10.66864  -46.51567 1.000 53.97652  ? 330 ASP B N   1 
ATOM   6940 C CA  . ASP B 1 331 ? 1.01545   11.92830  -45.99903 1.000 46.19057  ? 330 ASP B CA  1 
ATOM   6941 C C   . ASP B 1 331 ? 2.53431   11.93085  -45.90405 1.000 48.26543  ? 330 ASP B C   1 
ATOM   6942 O O   . ASP B 1 331 ? 3.08876   11.40158  -44.93442 1.000 49.90139  ? 330 ASP B O   1 
ATOM   6943 C CB  . ASP B 1 331 ? 0.42984   12.21095  -44.62004 1.000 41.33717  ? 330 ASP B CB  1 
ATOM   6944 C CG  . ASP B 1 331 ? 0.67464   13.62201  -44.17615 1.000 44.27094  ? 330 ASP B CG  1 
ATOM   6945 O OD1 . ASP B 1 331 ? 1.85396   13.97818  -43.96614 1.000 47.27086  ? 330 ASP B OD1 1 
ATOM   6946 O OD2 . ASP B 1 331 ? -0.31058  14.38311  -44.05375 1.000 40.94125  ? 330 ASP B OD2 1 
ATOM   6947 N N   . PRO B 1 332 ? 3.23657   12.53606  -46.86815 1.000 47.84266  ? 331 PRO B N   1 
ATOM   6948 C CA  . PRO B 1 332 ? 4.70477   12.44098  -46.87841 1.000 47.58978  ? 331 PRO B CA  1 
ATOM   6949 C C   . PRO B 1 332 ? 5.37426   13.19413  -45.73887 1.000 48.83974  ? 331 PRO B C   1 
ATOM   6950 O O   . PRO B 1 332 ? 6.52158   12.87170  -45.39736 1.000 45.89385  ? 331 PRO B O   1 
ATOM   6951 C CB  . PRO B 1 332 ? 5.09683   13.05732  -48.23030 1.000 40.41122  ? 331 PRO B CB  1 
ATOM   6952 C CG  . PRO B 1 332 ? 3.83824   13.61483  -48.81245 1.000 45.36747  ? 331 PRO B CG  1 
ATOM   6953 C CD  . PRO B 1 332 ? 2.76256   13.58537  -47.77590 1.000 46.05646  ? 331 PRO B CD  1 
ATOM   6954 N N   . TYR B 1 333 ? 4.72179   14.20347  -45.15665 1.000 44.21136  ? 332 TYR B N   1 
ATOM   6955 C CA  . TYR B 1 333 ? 5.36851   14.93010  -44.06949 1.000 49.00851  ? 332 TYR B CA  1 
ATOM   6956 C C   . TYR B 1 333 ? 5.37895   14.09926  -42.80463 1.000 48.47563  ? 332 TYR B C   1 
ATOM   6957 O O   . TYR B 1 333 ? 6.41084   13.97216  -42.13513 1.000 45.98341  ? 332 TYR B O   1 
ATOM   6958 C CB  . TYR B 1 333 ? 4.66626   16.24961  -43.79101 1.000 48.87044  ? 332 TYR B CB  1 
ATOM   6959 C CG  . TYR B 1 333 ? 5.01270   16.77252  -42.42475 1.000 48.28771  ? 332 TYR B CG  1 
ATOM   6960 C CD1 . TYR B 1 333 ? 6.27693   17.27541  -42.16451 1.000 51.45775  ? 332 TYR B CD1 1 
ATOM   6961 C CD2 . TYR B 1 333 ? 4.09079   16.73520  -41.38382 1.000 50.70601  ? 332 TYR B CD2 1 
ATOM   6962 C CE1 . TYR B 1 333 ? 6.61178   17.74901  -40.92078 1.000 50.90143  ? 332 TYR B CE1 1 
ATOM   6963 C CE2 . TYR B 1 333 ? 4.41926   17.21189  -40.12070 1.000 47.73806  ? 332 TYR B CE2 1 
ATOM   6964 C CZ  . TYR B 1 333 ? 5.68242   17.71823  -39.90353 1.000 49.69961  ? 332 TYR B CZ  1 
ATOM   6965 O OH  . TYR B 1 333 ? 6.03234   18.19860  -38.66920 1.000 53.06266  ? 332 TYR B OH  1 
ATOM   6966 N N   . LEU B 1 334 ? 4.21157   13.57019  -42.44624 1.000 47.89675  ? 333 LEU B N   1 
ATOM   6967 C CA  . LEU B 1 334 ? 4.11050   12.62623  -41.34950 1.000 43.73879  ? 333 LEU B CA  1 
ATOM   6968 C C   . LEU B 1 334 ? 5.06071   11.46004  -41.55956 1.000 46.97040  ? 333 LEU B C   1 
ATOM   6969 O O   . LEU B 1 334 ? 5.81161   11.08825  -40.64982 1.000 53.02953  ? 333 LEU B O   1 
ATOM   6970 C CB  . LEU B 1 334 ? 2.66427   12.17829  -41.24491 1.000 42.95782  ? 333 LEU B CB  1 
ATOM   6971 C CG  . LEU B 1 334 ? 2.02266   12.26474  -39.88246 1.000 42.72979  ? 333 LEU B CG  1 
ATOM   6972 C CD1 . LEU B 1 334 ? 2.26086   13.62785  -39.31276 1.000 46.44960  ? 333 LEU B CD1 1 
ATOM   6973 C CD2 . LEU B 1 334 ? 0.54483   12.13328  -40.16188 1.000 42.20382  ? 333 LEU B CD2 1 
ATOM   6974 N N   . ALA B 1 335 ? 5.09526   10.91439  -42.77320 1.000 42.54444  ? 334 ALA B N   1 
ATOM   6975 C CA  . ALA B 1 335 ? 6.06736   9.87397   -43.08667 1.000 43.34179  ? 334 ALA B CA  1 
ATOM   6976 C C   . ALA B 1 335 ? 7.51597   10.36091  -43.01278 1.000 48.00524  ? 334 ALA B C   1 
ATOM   6977 O O   . ALA B 1 335 ? 8.43264   9.54755   -42.82853 1.000 45.83410  ? 334 ALA B O   1 
ATOM   6978 C CB  . ALA B 1 335 ? 5.78149   9.30952   -44.47666 1.000 35.51432  ? 334 ALA B CB  1 
ATOM   6979 N N   . SER B 1 336 ? 7.76533   11.65504  -43.18248 1.000 47.82276  ? 335 SER B N   1 
ATOM   6980 C CA  . SER B 1 336 ? 9.16358   12.04961  -43.27026 1.000 50.93257  ? 335 SER B CA  1 
ATOM   6981 C C   . SER B 1 336 ? 9.80329   12.06580  -41.89569 1.000 54.05600  ? 335 SER B C   1 
ATOM   6982 O O   . SER B 1 336 ? 10.95839  11.65277  -41.75456 1.000 63.58798  ? 335 SER B O   1 
ATOM   6983 C CB  . SER B 1 336 ? 9.29884   13.40612  -43.96818 1.000 56.29100  ? 335 SER B CB  1 
ATOM   6984 O OG  . SER B 1 336 ? 9.12696   14.48183  -43.06202 1.000 59.89978  ? 335 SER B OG  1 
ATOM   6985 N N   . ILE B 1 337 ? 9.04351   12.50137  -40.87573 1.000 54.29558  ? 336 ILE B N   1 
ATOM   6986 C CA  . ILE B 1 337 ? 9.50727   12.57633  -39.48836 1.000 45.09225  ? 336 ILE B CA  1 
ATOM   6987 C C   . ILE B 1 337 ? 9.33836   11.26446  -38.73388 1.000 49.49704  ? 336 ILE B C   1 
ATOM   6988 O O   . ILE B 1 337 ? 9.69858   11.18692  -37.55023 1.000 57.64286  ? 336 ILE B O   1 
ATOM   6989 C CB  . ILE B 1 337 ? 8.76907   13.68255  -38.70158 1.000 40.74206  ? 336 ILE B CB  1 
ATOM   6990 C CG1 . ILE B 1 337 ? 7.36649   13.23228  -38.28946 1.000 40.43466  ? 336 ILE B CG1 1 
ATOM   6991 C CG2 . ILE B 1 337 ? 8.66981   14.95054  -39.52034 1.000 49.26144  ? 336 ILE B CG2 1 
ATOM   6992 C CD1 . ILE B 1 337 ? 6.62032   14.27269  -37.48518 1.000 40.19254  ? 336 ILE B CD1 1 
ATOM   6993 N N   . GLY B 1 338 ? 8.78959   10.23580  -39.36729 1.000 46.20173  ? 337 GLY B N   1 
ATOM   6994 C CA  . GLY B 1 338 ? 8.69267   8.94391   -38.72742 1.000 44.25462  ? 337 GLY B CA  1 
ATOM   6995 C C   . GLY B 1 338 ? 7.50157   8.76359   -37.82438 1.000 43.72741  ? 337 GLY B C   1 
ATOM   6996 O O   . GLY B 1 338 ? 7.43541   7.75371   -37.12215 1.000 46.83295  ? 337 GLY B O   1 
ATOM   6997 N N   . PHE B 1 339 ? 6.56329   9.70728   -37.81130 1.000 43.59100  ? 338 PHE B N   1 
ATOM   6998 C CA  . PHE B 1 339 ? 5.38361   9.56417   -36.97420 1.000 40.66953  ? 338 PHE B CA  1 
ATOM   6999 C C   . PHE B 1 339 ? 4.58554   8.33644   -37.37155 1.000 41.96726  ? 338 PHE B C   1 
ATOM   7000 O O   . PHE B 1 339 ? 4.50025   7.98586   -38.54888 1.000 48.80976  ? 338 PHE B O   1 
ATOM   7001 C CB  . PHE B 1 339 ? 4.48604   10.78539  -37.08170 1.000 44.69916  ? 338 PHE B CB  1 
ATOM   7002 C CG  . PHE B 1 339 ? 3.33654   10.75207  -36.12496 1.000 46.87326  ? 338 PHE B CG  1 
ATOM   7003 C CD1 . PHE B 1 339 ? 3.56193   10.76329  -34.75495 1.000 40.96817  ? 338 PHE B CD1 1 
ATOM   7004 C CD2 . PHE B 1 339 ? 2.03574   10.67162  -36.58205 1.000 44.88647  ? 338 PHE B CD2 1 
ATOM   7005 C CE1 . PHE B 1 339 ? 2.51518   10.72436  -33.86632 1.000 36.33560  ? 338 PHE B CE1 1 
ATOM   7006 C CE2 . PHE B 1 339 ? 0.97544   10.63386  -35.68408 1.000 46.58437  ? 338 PHE B CE2 1 
ATOM   7007 C CZ  . PHE B 1 339 ? 1.22247   10.65981  -34.32256 1.000 38.81753  ? 338 PHE B CZ  1 
ATOM   7008 N N   . GLU B 1 340 ? 3.99162   7.68123   -36.38026 1.000 45.55626  ? 339 GLU B N   1 
ATOM   7009 C CA  . GLU B 1 340 ? 3.18068   6.50229   -36.63945 1.000 46.52513  ? 339 GLU B CA  1 
ATOM   7010 C C   . GLU B 1 340 ? 2.02395   6.46298   -35.66085 1.000 41.91513  ? 339 GLU B C   1 
ATOM   7011 O O   . GLU B 1 340 ? 2.15285   6.88974   -34.51387 1.000 46.41060  ? 339 GLU B O   1 
ATOM   7012 C CB  . GLU B 1 340 ? 3.99456   5.21141   -36.53613 1.000 45.03979  ? 339 GLU B CB  1 
ATOM   7013 C CG  . GLU B 1 340 ? 4.95166   4.99818   -37.68270 1.000 47.21066  ? 339 GLU B CG  1 
ATOM   7014 C CD  . GLU B 1 340 ? 5.30758   3.54472   -37.88697 1.000 59.42824  ? 339 GLU B CD  1 
ATOM   7015 O OE1 . GLU B 1 340 ? 4.39289   2.73586   -38.16748 1.000 59.64053  ? 339 GLU B OE1 1 
ATOM   7016 O OE2 . GLU B 1 340 ? 6.50898   3.21317   -37.75910 1.000 67.71873  ? 339 GLU B OE2 1 
ATOM   7017 N N   . MET B 1 341 ? 0.89326   5.97608   -36.14412 1.000 42.34943  ? 340 MET B N   1 
ATOM   7018 C CA  . MET B 1 341 ? -0.26423  5.65318   -35.33508 1.000 40.55802  ? 340 MET B CA  1 
ATOM   7019 C C   . MET B 1 341 ? -0.42894  4.14371   -35.34376 1.000 41.53594  ? 340 MET B C   1 
ATOM   7020 O O   . MET B 1 341 ? -0.32889  3.50509   -36.39790 1.000 48.28202  ? 340 MET B O   1 
ATOM   7021 C CB  . MET B 1 341 ? -1.52899  6.30799   -35.89632 1.000 41.93333  ? 340 MET B CB  1 
ATOM   7022 C CG  . MET B 1 341 ? -1.95758  7.58875   -35.22999 1.000 44.55184  ? 340 MET B CG  1 
ATOM   7023 S SD  . MET B 1 341 ? -3.12980  8.49129   -36.26453 1.000 50.58920  ? 340 MET B SD  1 
ATOM   7024 C CE  . MET B 1 341 ? -2.21379  8.54002   -37.78492 1.000 45.15962  ? 340 MET B CE  1 
ATOM   7025 N N   . ILE B 1 342 ? -0.68297  3.56570   -34.18638 1.000 36.59090  ? 341 ILE B N   1 
ATOM   7026 C CA  . ILE B 1 342 ? -1.06627  2.16668   -34.12090 1.000 42.59985  ? 341 ILE B CA  1 
ATOM   7027 C C   . ILE B 1 342 ? -2.57731  2.08433   -33.90722 1.000 46.27237  ? 341 ILE B C   1 
ATOM   7028 O O   . ILE B 1 342 ? -3.12997  2.71509   -32.99314 1.000 44.14519  ? 341 ILE B O   1 
ATOM   7029 C CB  . ILE B 1 342 ? -0.29126  1.41841   -33.02890 1.000 41.67602  ? 341 ILE B CB  1 
ATOM   7030 C CG1 . ILE B 1 342 ? -0.23214  2.23392   -31.74177 1.000 45.01626  ? 341 ILE B CG1 1 
ATOM   7031 C CG2 . ILE B 1 342 ? 1.09674   1.13002   -33.52570 1.000 43.31832  ? 341 ILE B CG2 1 
ATOM   7032 C CD1 . ILE B 1 342 ? 0.36467   1.47900   -30.58805 1.000 46.14588  ? 341 ILE B CD1 1 
ATOM   7033 N N   . TYR B 1 343 ? -3.24364  1.29176   -34.74323 1.000 45.76148  ? 342 TYR B N   1 
ATOM   7034 C CA  . TYR B 1 343 ? -4.69151  1.30302   -34.85608 1.000 43.78121  ? 342 TYR B CA  1 
ATOM   7035 C C   . TYR B 1 343 ? -5.35302  0.20165   -34.03764 1.000 43.73421  ? 342 TYR B C   1 
ATOM   7036 O O   . TYR B 1 343 ? -4.76104  -0.83805  -33.72957 1.000 39.53269  ? 342 TYR B O   1 
ATOM   7037 C CB  . TYR B 1 343 ? -5.09770  1.17442   -36.31870 1.000 40.48117  ? 342 TYR B CB  1 
ATOM   7038 C CG  . TYR B 1 343 ? -4.64987  2.36262   -37.09945 1.000 43.60356  ? 342 TYR B CG  1 
ATOM   7039 C CD1 . TYR B 1 343 ? -5.30607  3.56911   -36.98060 1.000 40.44697  ? 342 TYR B CD1 1 
ATOM   7040 C CD2 . TYR B 1 343 ? -3.54674  2.29179   -37.92916 1.000 44.39883  ? 342 TYR B CD2 1 
ATOM   7041 C CE1 . TYR B 1 343 ? -4.88000  4.67494   -37.68061 1.000 46.78901  ? 342 TYR B CE1 1 
ATOM   7042 C CE2 . TYR B 1 343 ? -3.11902  3.38381   -38.63122 1.000 46.50880  ? 342 TYR B CE2 1 
ATOM   7043 C CZ  . TYR B 1 343 ? -3.78557  4.57653   -38.50773 1.000 46.87477  ? 342 TYR B CZ  1 
ATOM   7044 O OH  . TYR B 1 343 ? -3.35861  5.67448   -39.22258 1.000 51.77310  ? 342 TYR B OH  1 
ATOM   7045 N N   . GLU B 1 344 ? -6.60615  0.46274   -33.68246 1.000 39.28340  ? 343 GLU B N   1 
ATOM   7046 C CA  . GLU B 1 344 ? -7.48787  -0.54590  -33.11686 1.000 41.48375  ? 343 GLU B CA  1 
ATOM   7047 C C   . GLU B 1 344 ? -8.10533  -1.28432  -34.29695 1.000 42.05763  ? 343 GLU B C   1 
ATOM   7048 O O   . GLU B 1 344 ? -9.04843  -0.78878  -34.91147 1.000 41.50360  ? 343 GLU B O   1 
ATOM   7049 C CB  . GLU B 1 344 ? -8.54662  0.10686   -32.22959 1.000 43.32314  ? 343 GLU B CB  1 
ATOM   7050 C CG  . GLU B 1 344 ? -8.01979  0.71427   -30.93042 1.000 38.94867  ? 343 GLU B CG  1 
ATOM   7051 C CD  . GLU B 1 344 ? -8.03539  2.23416   -30.94523 1.000 47.53454  ? 343 GLU B CD  1 
ATOM   7052 O OE1 . GLU B 1 344 ? -9.05084  2.81141   -31.39503 1.000 49.31573  ? 343 GLU B OE1 1 
ATOM   7053 O OE2 . GLU B 1 344 ? -7.03662  2.85278   -30.50712 1.000 51.85193  ? 343 GLU B OE2 1 
ATOM   7054 N N   . VAL B 1 345 ? -7.58163  -2.47951  -34.60932 1.000 40.18651  ? 344 VAL B N   1 
ATOM   7055 C CA  . VAL B 1 345 ? -7.86331  -3.12164  -35.89482 1.000 38.22885  ? 344 VAL B CA  1 
ATOM   7056 C C   . VAL B 1 345 ? -9.16053  -3.92628  -35.88665 1.000 42.48671  ? 344 VAL B C   1 
ATOM   7057 O O   . VAL B 1 345 ? -9.81803  -4.03395  -36.92577 1.000 43.00751  ? 344 VAL B O   1 
ATOM   7058 C CB  . VAL B 1 345 ? -6.68509  -4.00891  -36.32192 1.000 37.68129  ? 344 VAL B CB  1 
ATOM   7059 C CG1 . VAL B 1 345 ? -5.46808  -3.16561  -36.55534 1.000 36.34481  ? 344 VAL B CG1 1 
ATOM   7060 C CG2 . VAL B 1 345 ? -6.40658  -5.06979  -35.26934 1.000 36.36954  ? 344 VAL B CG2 1 
ATOM   7061 N N   . ALA B 1 346 ? -9.54278  -4.52593  -34.75465 1.000 44.22041  ? 345 ALA B N   1 
ATOM   7062 C CA  . ALA B 1 346 ? -10.80919 -5.24983  -34.64596 1.000 40.27346  ? 345 ALA B CA  1 
ATOM   7063 C C   . ALA B 1 346 ? -11.42295 -5.01605  -33.27187 1.000 40.88053  ? 345 ALA B C   1 
ATOM   7064 O O   . ALA B 1 346 ? -10.73371 -4.65766  -32.31627 1.000 40.28357  ? 345 ALA B O   1 
ATOM   7065 C CB  . ALA B 1 346 ? -10.64655 -6.75560  -34.87990 1.000 35.87345  ? 345 ALA B CB  1 
ATOM   7066 N N   . ALA B 1 347 ? -12.73690 -5.22720  -33.18939 1.000 40.16194  ? 346 ALA B N   1 
ATOM   7067 C CA  . ALA B 1 347 ? -13.48801 -5.09536  -31.95025 1.000 34.05262  ? 346 ALA B CA  1 
ATOM   7068 C C   . ALA B 1 347 ? -14.62088 -6.10842  -31.95816 1.000 36.97320  ? 346 ALA B C   1 
ATOM   7069 O O   . ALA B 1 347 ? -15.03312 -6.60125  -33.00762 1.000 42.93381  ? 346 ALA B O   1 
ATOM   7070 C CB  . ALA B 1 347 ? -14.04076 -3.68202  -31.77229 1.000 34.89193  ? 346 ALA B CB  1 
ATOM   7071 N N   . ILE B 1 348 ? -15.13317 -6.41194  -30.77427 1.000 39.33890  ? 347 ILE B N   1 
ATOM   7072 C CA  . ILE B 1 348 ? -16.14259 -7.45466  -30.62428 1.000 36.10122  ? 347 ILE B CA  1 
ATOM   7073 C C   . ILE B 1 348 ? -16.88164 -7.18101  -29.32582 1.000 40.04459  ? 347 ILE B C   1 
ATOM   7074 O O   . ILE B 1 348 ? -16.27922 -6.75079  -28.33635 1.000 38.91598  ? 347 ILE B O   1 
ATOM   7075 C CB  . ILE B 1 348 ? -15.48237 -8.85037  -30.64361 1.000 36.97907  ? 347 ILE B CB  1 
ATOM   7076 C CG1 . ILE B 1 348 ? -16.48779 -9.96188  -30.43086 1.000 32.09747  ? 347 ILE B CG1 1 
ATOM   7077 C CG2 . ILE B 1 348 ? -14.38127 -8.92573  -29.60400 1.000 40.74047  ? 347 ILE B CG2 1 
ATOM   7078 C CD1 . ILE B 1 348 ? -15.95744 -11.27628 -30.98231 1.000 30.07960  ? 347 ILE B CD1 1 
ATOM   7079 N N   . GLY B 1 349 ? -18.19838 -7.39072  -29.35073 1.000 39.08724  ? 348 GLY B N   1 
ATOM   7080 C CA  . GLY B 1 349 ? -19.06872 -7.02296  -28.24998 1.000 34.67556  ? 348 GLY B CA  1 
ATOM   7081 C C   . GLY B 1 349 ? -20.37320 -7.80075  -28.20229 1.000 39.65265  ? 348 GLY B C   1 
ATOM   7082 O O   . GLY B 1 349 ? -21.07634 -7.91386  -29.20591 1.000 39.55761  ? 348 GLY B O   1 
ATOM   7083 N N   . TYR B 1 350 ? -20.70419 -8.33319  -27.02567 1.000 44.05781  ? 349 TYR B N   1 
ATOM   7084 C CA  . TYR B 1 350 ? -21.86849 -9.18403  -26.81348 1.000 35.09379  ? 349 TYR B CA  1 
ATOM   7085 C C   . TYR B 1 350 ? -23.04614 -8.34213  -26.34949 1.000 41.46411  ? 349 TYR B C   1 
ATOM   7086 O O   . TYR B 1 350 ? -22.89304 -7.49239  -25.46199 1.000 42.67157  ? 349 TYR B O   1 
ATOM   7087 C CB  . TYR B 1 350 ? -21.54236 -10.23944 -25.76135 1.000 37.67085  ? 349 TYR B CB  1 
ATOM   7088 C CG  . TYR B 1 350 ? -22.56852 -11.32191 -25.62029 1.000 43.49044  ? 349 TYR B CG  1 
ATOM   7089 C CD1 . TYR B 1 350 ? -22.56608 -12.41365 -26.48408 1.000 45.77309  ? 349 TYR B CD1 1 
ATOM   7090 C CD2 . TYR B 1 350 ? -23.52811 -11.27482 -24.61767 1.000 41.95709  ? 349 TYR B CD2 1 
ATOM   7091 C CE1 . TYR B 1 350 ? -23.49269 -13.42397 -26.36538 1.000 42.66892  ? 349 TYR B CE1 1 
ATOM   7092 C CE2 . TYR B 1 350 ? -24.46820 -12.28104 -24.48914 1.000 44.72184  ? 349 TYR B CE2 1 
ATOM   7093 C CZ  . TYR B 1 350 ? -24.44371 -13.35116 -25.37497 1.000 47.20249  ? 349 TYR B CZ  1 
ATOM   7094 O OH  . TYR B 1 350 ? -25.36767 -14.36150 -25.28512 1.000 48.14802  ? 349 TYR B OH  1 
ATOM   7095 N N   . ARG B 1 351 ? -24.21410 -8.56825  -26.95514 1.000 42.68428  ? 350 ARG B N   1 
ATOM   7096 C CA  . ARG B 1 351 ? -25.46549 -7.93449  -26.53723 1.000 45.40168  ? 350 ARG B CA  1 
ATOM   7097 C C   . ARG B 1 351 ? -26.40325 -9.02604  -26.04468 1.000 47.91609  ? 350 ARG B C   1 
ATOM   7098 O O   . ARG B 1 351 ? -26.89495 -9.83665  -26.83451 1.000 55.90867  ? 350 ARG B O   1 
ATOM   7099 C CB  . ARG B 1 351 ? -26.12829 -7.14128  -27.66456 1.000 43.20929  ? 350 ARG B CB  1 
ATOM   7100 C CG  . ARG B 1 351 ? -25.23828 -6.15107  -28.39835 1.000 49.92724  ? 350 ARG B CG  1 
ATOM   7101 C CD  . ARG B 1 351 ? -25.40702 -6.28091  -29.91765 1.000 56.27204  ? 350 ARG B CD  1 
ATOM   7102 N NE  . ARG B 1 351 ? -26.52336 -7.15300  -30.27221 1.000 56.11098  ? 350 ARG B NE  1 
ATOM   7103 C CZ  . ARG B 1 351 ? -26.58813 -7.90080  -31.36802 1.000 58.55788  ? 350 ARG B CZ  1 
ATOM   7104 N NH1 . ARG B 1 351 ? -25.62358 -7.88438  -32.27857 1.000 58.66628  ? 350 ARG B NH1 1 
ATOM   7105 N NH2 . ARG B 1 351 ? -27.64459 -8.69379  -31.55093 1.000 60.36313  ? 350 ARG B NH2 1 
ATOM   7106 N N   . ASN B 1 352 ? -26.63960 -9.06120  -24.74550 1.000 51.18704  ? 351 ASN B N   1 
ATOM   7107 C CA  . ASN B 1 352 ? -27.63463 -9.96353  -24.19495 1.000 51.59184  ? 351 ASN B CA  1 
ATOM   7108 C C   . ASN B 1 352 ? -29.00571 -9.34784  -24.42445 1.000 55.50193  ? 351 ASN B C   1 
ATOM   7109 O O   . ASN B 1 352 ? -29.21794 -8.17012  -24.12466 1.000 60.97897  ? 351 ASN B O   1 
ATOM   7110 C CB  . ASN B 1 352 ? -27.36079 -10.19750 -22.71115 1.000 51.08219  ? 351 ASN B CB  1 
ATOM   7111 C CG  . ASN B 1 352 ? -28.59617 -10.56046 -21.94630 1.000 59.01681  ? 351 ASN B CG  1 
ATOM   7112 O OD1 . ASN B 1 352 ? -29.40139 -9.69613  -21.59633 1.000 57.19625  ? 351 ASN B OD1 1 
ATOM   7113 N ND2 . ASN B 1 352 ? -28.76608 -11.85127 -21.68039 1.000 69.64184  ? 351 ASN B ND2 1 
ATOM   7114 N N   . THR B 1 353 ? -29.92975 -10.12755 -24.98150 1.000 56.36145  ? 352 THR B N   1 
ATOM   7115 C CA  . THR B 1 353 ? -31.20258 -9.55059  -25.40625 1.000 55.42133  ? 352 THR B CA  1 
ATOM   7116 C C   . THR B 1 353 ? -31.91788 -8.87279  -24.24293 1.000 60.36887  ? 352 THR B C   1 
ATOM   7117 O O   . THR B 1 353 ? -32.38186 -7.73086  -24.35541 1.000 58.48669  ? 352 THR B O   1 
ATOM   7118 C CB  . THR B 1 353 ? -32.08691 -10.63678 -26.01027 1.000 55.63115  ? 352 THR B CB  1 
ATOM   7119 O OG1 . THR B 1 353 ? -31.32505 -11.39807 -26.95694 1.000 68.45068  ? 352 THR B OG1 1 
ATOM   7120 C CG2 . THR B 1 353 ? -33.28031 -10.01138 -26.69759 1.000 53.00325  ? 352 THR B CG2 1 
ATOM   7121 N N   . THR B 1 354 ? -31.98531 -9.56114  -23.10232 1.000 62.03049  ? 353 THR B N   1 
ATOM   7122 C CA  . THR B 1 354 ? -32.82078 -9.11808  -21.99307 1.000 54.55838  ? 353 THR B CA  1 
ATOM   7123 C C   . THR B 1 354 ? -32.27683 -7.85497  -21.34921 1.000 54.11829  ? 353 THR B C   1 
ATOM   7124 O O   . THR B 1 354 ? -33.04758 -6.98419  -20.93652 1.000 57.80628  ? 353 THR B O   1 
ATOM   7125 C CB  . THR B 1 354 ? -32.92131 -10.23712 -20.96213 1.000 58.65788  ? 353 THR B CB  1 
ATOM   7126 O OG1 . THR B 1 354 ? -33.01225 -11.50199 -21.64497 1.000 61.30239  ? 353 THR B OG1 1 
ATOM   7127 C CG2 . THR B 1 354 ? -34.12696 -10.02846 -20.06875 1.000 46.64806  ? 353 THR B CG2 1 
ATOM   7128 N N   . LEU B 1 355 ? -30.95484 -7.74377  -21.23100 1.000 55.14164  ? 354 LEU B N   1 
ATOM   7129 C CA  . LEU B 1 355 ? -30.38587 -6.55732  -20.60786 1.000 50.50812  ? 354 LEU B CA  1 
ATOM   7130 C C   . LEU B 1 355 ? -30.56448 -5.33713  -21.49749 1.000 53.23603  ? 354 LEU B C   1 
ATOM   7131 O O   . LEU B 1 355 ? -30.82677 -4.24108  -20.99266 1.000 54.25843  ? 354 LEU B O   1 
ATOM   7132 C CB  . LEU B 1 355 ? -28.90795 -6.77535  -20.28819 1.000 49.03976  ? 354 LEU B CB  1 
ATOM   7133 C CG  . LEU B 1 355 ? -28.50002 -7.40751  -18.95471 1.000 44.92910  ? 354 LEU B CG  1 
ATOM   7134 C CD1 . LEU B 1 355 ? -26.99274 -7.43987  -18.86680 1.000 43.11535  ? 354 LEU B CD1 1 
ATOM   7135 C CD2 . LEU B 1 355 ? -29.08262 -6.65826  -17.77760 1.000 43.16891  ? 354 LEU B CD2 1 
ATOM   7136 N N   . THR B 1 356 ? -30.43319 -5.50269  -22.82446 1.000 51.65240  ? 355 THR B N   1 
ATOM   7137 C CA  . THR B 1 356 ? -30.56834 -4.35623  -23.72753 1.000 54.60951  ? 355 THR B CA  1 
ATOM   7138 C C   . THR B 1 356 ? -31.97112 -3.77617  -23.66322 1.000 57.40190  ? 355 THR B C   1 
ATOM   7139 O O   . THR B 1 356 ? -32.14943 -2.54976  -23.66552 1.000 57.55292  ? 355 THR B O   1 
ATOM   7140 C CB  . THR B 1 356 ? -30.25677 -4.74389  -25.17531 1.000 56.74106  ? 355 THR B CB  1 
ATOM   7141 O OG1 . THR B 1 356 ? -29.25564 -5.76374  -25.21777 1.000 60.88690  ? 355 THR B OG1 1 
ATOM   7142 C CG2 . THR B 1 356 ? -29.75732 -3.54118  -25.93778 1.000 52.38104  ? 355 THR B CG2 1 
ATOM   7143 N N   . ALA B 1 357 ? -32.97683 -4.65443  -23.60816 1.000 54.10276  ? 356 ALA B N   1 
ATOM   7144 C CA  . ALA B 1 357 ? -34.36772 -4.22736  -23.53582 1.000 49.77072  ? 356 ALA B CA  1 
ATOM   7145 C C   . ALA B 1 357 ? -34.64602 -3.40058  -22.28325 1.000 53.70773  ? 356 ALA B C   1 
ATOM   7146 O O   . ALA B 1 357 ? -35.29754 -2.35368  -22.35399 1.000 63.03249  ? 356 ALA B O   1 
ATOM   7147 C CB  . ALA B 1 357 ? -35.27515 -5.45065  -23.58311 1.000 51.07311  ? 356 ALA B CB  1 
ATOM   7148 N N   . ILE B 1 358 ? -34.16316 -3.84708  -21.12633 1.000 52.17464  ? 357 ILE B N   1 
ATOM   7149 C CA  . ILE B 1 358 ? -34.54568 -3.20647  -19.87236 1.000 53.46759  ? 357 ILE B CA  1 
ATOM   7150 C C   . ILE B 1 358 ? -33.57511 -2.10355  -19.46676 1.000 53.61202  ? 357 ILE B C   1 
ATOM   7151 O O   . ILE B 1 358 ? -33.67411 -1.56857  -18.35255 1.000 57.00017  ? 357 ILE B O   1 
ATOM   7152 C CB  . ILE B 1 358 ? -34.67644 -4.24047  -18.74261 1.000 47.59896  ? 357 ILE B CB  1 
ATOM   7153 C CG1 . ILE B 1 358 ? -33.30828 -4.57600  -18.16961 1.000 50.18998  ? 357 ILE B CG1 1 
ATOM   7154 C CG2 . ILE B 1 358 ? -35.33734 -5.49631  -19.25168 1.000 51.20570  ? 357 ILE B CG2 1 
ATOM   7155 C CD1 . ILE B 1 358 ? -33.36257 -5.00276  -16.71776 1.000 56.49338  ? 357 ILE B CD1 1 
ATOM   7156 N N   . THR B 1 359 ? -32.64167 -1.74448  -20.35655 1.000 51.62280  ? 358 THR B N   1 
ATOM   7157 C CA  . THR B 1 359 ? -31.64962 -0.71419  -20.06045 1.000 52.30487  ? 358 THR B CA  1 
ATOM   7158 C C   . THR B 1 359 ? -31.55371 0.29393   -21.19784 1.000 56.09334  ? 358 THR B C   1 
ATOM   7159 O O   . THR B 1 359 ? -31.73775 -0.03453  -22.37651 1.000 51.85817  ? 358 THR B O   1 
ATOM   7160 C CB  . THR B 1 359 ? -30.22167 -1.27924  -19.80624 1.000 49.49397  ? 358 THR B CB  1 
ATOM   7161 O OG1 . THR B 1 359 ? -29.70224 -1.87838  -20.99991 1.000 53.32347  ? 358 THR B OG1 1 
ATOM   7162 C CG2 . THR B 1 359 ? -30.20632 -2.29721  -18.68443 1.000 50.30653  ? 358 THR B CG2 1 
ATOM   7163 N N   . ARG B 1 360 ? -31.25203 1.52977   -20.81382 1.000 57.91015  ? 359 ARG B N   1 
ATOM   7164 C CA  . ARG B 1 360 ? -30.92701 2.60839   -21.72877 1.000 60.58179  ? 359 ARG B CA  1 
ATOM   7165 C C   . ARG B 1 360 ? -29.48159 2.47305   -22.20827 1.000 58.14564  ? 359 ARG B C   1 
ATOM   7166 O O   . ARG B 1 360 ? -28.66254 1.81768   -21.55982 1.000 58.36823  ? 359 ARG B O   1 
ATOM   7167 C CB  . ARG B 1 360 ? -31.13513 3.95472   -21.03425 1.000 55.76656  ? 359 ARG B CB  1 
ATOM   7168 N N   . PRO B 1 361 ? -29.14766 3.04701   -23.36689 1.000 62.42068  ? 360 PRO B N   1 
ATOM   7169 C CA  . PRO B 1 361 ? -27.73842 3.06794   -23.78706 1.000 64.66920  ? 360 PRO B CA  1 
ATOM   7170 C C   . PRO B 1 361 ? -26.87638 3.79344   -22.76370 1.000 63.45020  ? 360 PRO B C   1 
ATOM   7171 O O   . PRO B 1 361 ? -27.32745 4.71717   -22.07791 1.000 52.04921  ? 360 PRO B O   1 
ATOM   7172 C CB  . PRO B 1 361 ? -27.75976 3.81242   -25.12852 1.000 55.69880  ? 360 PRO B CB  1 
ATOM   7173 C CG  . PRO B 1 361 ? -29.16635 3.86082   -25.55955 1.000 58.09049  ? 360 PRO B CG  1 
ATOM   7174 C CD  . PRO B 1 361 ? -30.07187 3.41084   -24.45415 1.000 60.30074  ? 360 PRO B CD  1 
ATOM   7175 N N   . GLY B 1 362 ? -25.61828 3.35271   -22.66308 1.000 60.90162  ? 361 GLY B N   1 
ATOM   7176 C CA  . GLY B 1 362 ? -24.69127 3.88578   -21.68874 1.000 53.91868  ? 361 GLY B CA  1 
ATOM   7177 C C   . GLY B 1 362 ? -24.70939 3.18964   -20.35008 1.000 54.62719  ? 361 GLY B C   1 
ATOM   7178 O O   . GLY B 1 362 ? -23.82975 3.45628   -19.51920 1.000 57.37259  ? 361 GLY B O   1 
ATOM   7179 N N   . SER B 1 363 ? -25.68142 2.31122   -20.11395 1.000 54.08878  ? 362 SER B N   1 
ATOM   7180 C CA  . SER B 1 363 ? -25.72045 1.55460   -18.87620 1.000 44.56101  ? 362 SER B CA  1 
ATOM   7181 C C   . SER B 1 363 ? -24.44073 0.74731   -18.72962 1.000 48.08278  ? 362 SER B C   1 
ATOM   7182 O O   . SER B 1 363 ? -23.84705 0.29264   -19.71244 1.000 49.16294  ? 362 SER B O   1 
ATOM   7183 C CB  . SER B 1 363 ? -26.94211 0.63480   -18.85449 1.000 44.51063  ? 362 SER B CB  1 
ATOM   7184 O OG  . SER B 1 363 ? -26.93854 -0.23680  -17.73576 1.000 42.80720  ? 362 SER B OG  1 
ATOM   7185 N N   . GLU B 1 364 ? -23.99363 0.60596   -17.48172 1.000 53.65500  ? 363 GLU B N   1 
ATOM   7186 C CA  . GLU B 1 364 ? -22.85687 -0.25800  -17.19613 1.000 47.43959  ? 363 GLU B CA  1 
ATOM   7187 C C   . GLU B 1 364 ? -23.13900 -1.70914  -17.57969 1.000 47.27859  ? 363 GLU B C   1 
ATOM   7188 O O   . GLU B 1 364 ? -22.19296 -2.46993  -17.82307 1.000 46.86229  ? 363 GLU B O   1 
ATOM   7189 C CB  . GLU B 1 364 ? -22.48531 -0.14942  -15.71399 1.000 39.42260  ? 363 GLU B CB  1 
ATOM   7190 C CG  . GLU B 1 364 ? -22.04301 1.23995   -15.25277 1.000 44.39474  ? 363 GLU B CG  1 
ATOM   7191 C CD  . GLU B 1 364 ? -21.12641 1.96571   -16.25508 1.000 65.58185  ? 363 GLU B CD  1 
ATOM   7192 O OE1 . GLU B 1 364 ? -20.00976 1.46741   -16.53837 1.000 69.84080  ? 363 GLU B OE1 1 
ATOM   7193 O OE2 . GLU B 1 364 ? -21.51221 3.05080   -16.75674 1.000 71.35100  ? 363 GLU B OE2 1 
ATOM   7194 N N   . TYR B 1 365 ? -24.41922 -2.10199  -17.66171 1.000 42.24168  ? 364 TYR B N   1 
ATOM   7195 C CA  . TYR B 1 365 ? -24.77105 -3.47213  -18.01544 1.000 43.94900  ? 364 TYR B CA  1 
ATOM   7196 C C   . TYR B 1 365 ? -24.52413 -3.77105  -19.48481 1.000 49.78615  ? 364 TYR B C   1 
ATOM   7197 O O   . TYR B 1 365 ? -24.51064 -4.95017  -19.87580 1.000 45.05660  ? 364 TYR B O   1 
ATOM   7198 C CB  . TYR B 1 365 ? -26.22717 -3.73959  -17.64865 1.000 43.71716  ? 364 TYR B CB  1 
ATOM   7199 C CG  . TYR B 1 365 ? -26.36926 -3.89204  -16.16928 1.000 49.04024  ? 364 TYR B CG  1 
ATOM   7200 C CD1 . TYR B 1 365 ? -25.95789 -5.06103  -15.53708 1.000 50.23391  ? 364 TYR B CD1 1 
ATOM   7201 C CD2 . TYR B 1 365 ? -26.85895 -2.85828  -15.38412 1.000 44.37724  ? 364 TYR B CD2 1 
ATOM   7202 C CE1 . TYR B 1 365 ? -26.05825 -5.20664  -14.15763 1.000 46.83173  ? 364 TYR B CE1 1 
ATOM   7203 C CE2 . TYR B 1 365 ? -26.96611 -3.00219  -14.00543 1.000 43.60504  ? 364 TYR B CE2 1 
ATOM   7204 C CZ  . TYR B 1 365 ? -26.56043 -4.17503  -13.40146 1.000 43.71233  ? 364 TYR B CZ  1 
ATOM   7205 O OH  . TYR B 1 365 ? -26.66151 -4.33074  -12.03981 1.000 45.26597  ? 364 TYR B OH  1 
ATOM   7206 N N   . ARG B 1 366 ? -24.33667 -2.72611  -20.29577 1.000 52.48863  ? 365 ARG B N   1 
ATOM   7207 C CA  . ARG B 1 366 ? -23.96347 -2.83225  -21.69693 1.000 47.20843  ? 365 ARG B CA  1 
ATOM   7208 C C   . ARG B 1 366 ? -22.46642 -2.72193  -21.89925 1.000 45.63953  ? 365 ARG B C   1 
ATOM   7209 O O   . ARG B 1 366 ? -22.01835 -2.64590  -23.04897 1.000 48.04899  ? 365 ARG B O   1 
ATOM   7210 C CB  . ARG B 1 366 ? -24.65715 -1.74579  -22.51616 1.000 45.63881  ? 365 ARG B CB  1 
ATOM   7211 C CG  . ARG B 1 366 ? -26.14635 -1.67249  -22.33872 1.000 46.63741  ? 365 ARG B CG  1 
ATOM   7212 C CD  . ARG B 1 366 ? -26.75922 -1.01287  -23.53448 1.000 55.38135  ? 365 ARG B CD  1 
ATOM   7213 N NE  . ARG B 1 366 ? -28.20893 -1.10318  -23.49559 1.000 56.15787  ? 365 ARG B NE  1 
ATOM   7214 C CZ  . ARG B 1 366 ? -29.00096 -0.63089  -24.44353 1.000 54.76943  ? 365 ARG B CZ  1 
ATOM   7215 N NH1 . ARG B 1 366 ? -28.51100 -0.00359  -25.50009 1.000 50.61048  ? 365 ARG B NH1 1 
ATOM   7216 N NH2 . ARG B 1 366 ? -30.31498 -0.80026  -24.33175 1.000 58.34366  ? 365 ARG B NH2 1 
ATOM   7217 N N   . LYS B 1 367 ? -21.68230 -2.71281  -20.81703 1.000 40.73157  ? 366 LYS B N   1 
ATOM   7218 C CA  . LYS B 1 367 ? -20.24291 -2.50875  -20.92082 1.000 40.36774  ? 366 LYS B CA  1 
ATOM   7219 C C   . LYS B 1 367 ? -19.43393 -3.67235  -20.35393 1.000 38.16249  ? 366 LYS B C   1 
ATOM   7220 O O   . LYS B 1 367 ? -18.24981 -3.49589  -20.05497 1.000 36.93245  ? 366 LYS B O   1 
ATOM   7221 C CB  . LYS B 1 367 ? -19.84584 -1.19893  -20.24011 1.000 37.32698  ? 366 LYS B CB  1 
ATOM   7222 C CG  . LYS B 1 367 ? -20.55681 0.02813   -20.80274 1.000 45.35223  ? 366 LYS B CG  1 
ATOM   7223 C CD  . LYS B 1 367 ? -20.37341 1.23086   -19.88254 1.000 53.86423  ? 366 LYS B CD  1 
ATOM   7224 C CE  . LYS B 1 367 ? -20.18645 2.52098   -20.65236 1.000 48.40870  ? 366 LYS B CE  1 
ATOM   7225 N NZ  . LYS B 1 367 ? -18.87710 3.10214   -20.26511 1.000 51.75872  ? 366 LYS B NZ  1 
ATOM   7226 N N   . LEU B 1 368 ? -20.02444 -4.86774  -20.24286 1.000 37.84880  ? 367 LEU B N   1 
ATOM   7227 C CA  . LEU B 1 368 ? -19.38084 -5.97956  -19.54150 1.000 36.29550  ? 367 LEU B CA  1 
ATOM   7228 C C   . LEU B 1 368 ? -18.48282 -6.83185  -20.43322 1.000 36.26376  ? 367 LEU B C   1 
ATOM   7229 O O   . LEU B 1 368 ? -17.35121 -7.13357  -20.05233 1.000 39.13825  ? 367 LEU B O   1 
ATOM   7230 C CB  . LEU B 1 368 ? -20.43552 -6.88169  -18.89320 1.000 39.96360  ? 367 LEU B CB  1 
ATOM   7231 C CG  . LEU B 1 368 ? -21.47846 -6.18157  -18.01670 1.000 42.68172  ? 367 LEU B CG  1 
ATOM   7232 C CD1 . LEU B 1 368 ? -22.56671 -7.16248  -17.62530 1.000 40.32458  ? 367 LEU B CD1 1 
ATOM   7233 C CD2 . LEU B 1 368 ? -20.82888 -5.55954  -16.79437 1.000 33.49762  ? 367 LEU B CD2 1 
ATOM   7234 N N   . LEU B 1 369 ? -18.97291 -7.25347  -21.59786 1.000 37.26039  ? 368 LEU B N   1 
ATOM   7235 C CA  . LEU B 1 369 ? -18.30744 -8.24954  -22.44530 1.000 35.49674  ? 368 LEU B CA  1 
ATOM   7236 C C   . LEU B 1 369 ? -17.96440 -7.63364  -23.80555 1.000 38.14179  ? 368 LEU B C   1 
ATOM   7237 O O   . LEU B 1 369 ? -18.80081 -7.60117  -24.71334 1.000 40.40081  ? 368 LEU B O   1 
ATOM   7238 C CB  . LEU B 1 369 ? -19.19672 -9.47992  -22.60011 1.000 35.57775  ? 368 LEU B CB  1 
ATOM   7239 C CG  . LEU B 1 369 ? -18.56720 -10.74267 -23.16458 1.000 35.84606  ? 368 LEU B CG  1 
ATOM   7240 C CD1 . LEU B 1 369 ? -17.09633 -10.86246 -22.75200 1.000 33.95917  ? 368 LEU B CD1 1 
ATOM   7241 C CD2 . LEU B 1 369 ? -19.37412 -11.92473 -22.67477 1.000 35.63425  ? 368 LEU B CD2 1 
ATOM   7242 N N   . SER B 1 370 ? -16.72643 -7.16199  -23.94202 1.000 35.49697  ? 369 SER B N   1 
ATOM   7243 C CA  . SER B 1 370 ? -16.25888 -6.39731  -25.08534 1.000 30.71255  ? 369 SER B CA  1 
ATOM   7244 C C   . SER B 1 370 ? -14.74815 -6.49089  -25.14464 1.000 34.23696  ? 369 SER B C   1 
ATOM   7245 O O   . SER B 1 370 ? -14.07878 -6.43977  -24.11634 1.000 34.73823  ? 369 SER B O   1 
ATOM   7246 C CB  . SER B 1 370 ? -16.65141 -4.92202  -24.99918 1.000 34.52249  ? 369 SER B CB  1 
ATOM   7247 O OG  . SER B 1 370 ? -18.03104 -4.75400  -24.76308 1.000 44.20280  ? 369 SER B OG  1 
ATOM   7248 N N   . ALA B 1 371 ? -14.21344 -6.59792  -26.34922 1.000 38.04364  ? 370 ALA B N   1 
ATOM   7249 C CA  . ALA B 1 371 ? -12.77482 -6.55422  -26.50666 1.000 35.21742  ? 370 ALA B CA  1 
ATOM   7250 C C   . ALA B 1 371 ? -12.48373 -5.89180  -27.83679 1.000 38.30556  ? 370 ALA B C   1 
ATOM   7251 O O   . ALA B 1 371 ? -13.37082 -5.71325  -28.67835 1.000 34.34332  ? 370 ALA B O   1 
ATOM   7252 C CB  . ALA B 1 371 ? -12.14061 -7.94994  -26.41968 1.000 30.89202  ? 370 ALA B CB  1 
ATOM   7253 N N   . LEU B 1 372 ? -11.22569 -5.50222  -27.99081 1.000 33.34011  ? 371 LEU B N   1 
ATOM   7254 C CA  . LEU B 1 372 ? -10.71837 -4.98935  -29.23980 1.000 33.90121  ? 371 LEU B CA  1 
ATOM   7255 C C   . LEU B 1 372 ? -9.22412  -5.25118  -29.26053 1.000 37.34903  ? 371 LEU B C   1 
ATOM   7256 O O   . LEU B 1 372 ? -8.60048  -5.42612  -28.21274 1.000 37.18564  ? 371 LEU B O   1 
ATOM   7257 C CB  . LEU B 1 372 ? -11.03695 -3.50120  -29.41311 1.000 37.34749  ? 371 LEU B CB  1 
ATOM   7258 C CG  . LEU B 1 372 ? -10.56952 -2.45656  -28.40792 1.000 39.15380  ? 371 LEU B CG  1 
ATOM   7259 C CD1 . LEU B 1 372 ? -9.22131  -1.92794  -28.83168 1.000 38.89442  ? 371 LEU B CD1 1 
ATOM   7260 C CD2 . LEU B 1 372 ? -11.57831 -1.32526  -28.33904 1.000 33.39519  ? 371 LEU B CD2 1 
ATOM   7261 N N   . TRP B 1 373 ? -8.65979  -5.31049  -30.46754 1.000 37.28534  ? 372 TRP B N   1 
ATOM   7262 C CA  . TRP B 1 373 ? -7.23848  -5.55047  -30.65424 1.000 34.98532  ? 372 TRP B CA  1 
ATOM   7263 C C   . TRP B 1 373 ? -6.55512  -4.30129  -31.18443 1.000 38.89491  ? 372 TRP B C   1 
ATOM   7264 O O   . TRP B 1 373 ? -7.16314  -3.49907  -31.89451 1.000 42.57642  ? 372 TRP B O   1 
ATOM   7265 C CB  . TRP B 1 373 ? -6.98461  -6.68957  -31.62064 1.000 29.83660  ? 372 TRP B CB  1 
ATOM   7266 C CG  . TRP B 1 373 ? -7.38308  -8.01487  -31.13080 1.000 31.33426  ? 372 TRP B CG  1 
ATOM   7267 C CD1 . TRP B 1 373 ? -6.56777  -8.98140  -30.61717 1.000 35.15377  ? 372 TRP B CD1 1 
ATOM   7268 C CD2 . TRP B 1 373 ? -8.69937  -8.56573  -31.14434 1.000 36.80797  ? 372 TRP B CD2 1 
ATOM   7269 N NE1 . TRP B 1 373 ? -7.29987  -10.10495 -30.30305 1.000 34.98828  ? 372 TRP B NE1 1 
ATOM   7270 C CE2 . TRP B 1 373 ? -8.61306  -9.87209  -30.61274 1.000 32.93984  ? 372 TRP B CE2 1 
ATOM   7271 C CE3 . TRP B 1 373 ? -9.94681  -8.08619  -31.56333 1.000 38.09517  ? 372 TRP B CE3 1 
ATOM   7272 C CZ2 . TRP B 1 373 ? -9.72282  -10.70320 -30.49025 1.000 35.07744  ? 372 TRP B CZ2 1 
ATOM   7273 C CZ3 . TRP B 1 373 ? -11.05453 -8.91406  -31.42949 1.000 38.42781  ? 372 TRP B CZ3 1 
ATOM   7274 C CH2 . TRP B 1 373 ? -10.93193 -10.21199 -30.90558 1.000 35.89961  ? 372 TRP B CH2 1 
ATOM   7275 N N   . ARG B 1 374 ? -5.27719  -4.15589  -30.84440 1.000 34.22148  ? 373 ARG B N   1 
ATOM   7276 C CA  . ARG B 1 374 ? -4.48031  -3.00912  -31.24847 1.000 36.15502  ? 373 ARG B CA  1 
ATOM   7277 C C   . ARG B 1 374 ? -3.11820  -3.49982  -31.70984 1.000 39.96076  ? 373 ARG B C   1 
ATOM   7278 O O   . ARG B 1 374 ? -2.50400  -4.31767  -31.02211 1.000 43.36374  ? 373 ARG B O   1 
ATOM   7279 C CB  . ARG B 1 374 ? -4.30916  -2.01421  -30.10101 1.000 35.37270  ? 373 ARG B CB  1 
ATOM   7280 C CG  . ARG B 1 374 ? -3.06099  -1.17055  -30.27133 1.000 41.67295  ? 373 ARG B CG  1 
ATOM   7281 C CD  . ARG B 1 374 ? -2.98846  -0.06910  -29.26659 1.000 44.64285  ? 373 ARG B CD  1 
ATOM   7282 N NE  . ARG B 1 374 ? -4.28915  0.54074   -29.02527 1.000 47.26308  ? 373 ARG B NE  1 
ATOM   7283 C CZ  . ARG B 1 374 ? -4.69162  0.95368   -27.83153 1.000 49.82035  ? 373 ARG B CZ  1 
ATOM   7284 N NH1 . ARG B 1 374 ? -3.92098  0.81047   -26.75752 1.000 45.99459  ? 373 ARG B NH1 1 
ATOM   7285 N NH2 . ARG B 1 374 ? -5.88976  1.52623   -27.71183 1.000 43.20653  ? 373 ARG B NH2 1 
ATOM   7286 N N   . GLU B 1 375 ? -2.64545  -3.00059  -32.85526 1.000 36.64418  ? 374 GLU B N   1 
ATOM   7287 C CA  . GLU B 1 375 ? -1.37184  -3.45255  -33.39571 1.000 35.88075  ? 374 GLU B CA  1 
ATOM   7288 C C   . GLU B 1 375 ? -0.24651  -3.24431  -32.39447 1.000 42.22258  ? 374 GLU B C   1 
ATOM   7289 O O   . GLU B 1 375 ? -0.17663  -2.21294  -31.72054 1.000 45.96982  ? 374 GLU B O   1 
ATOM   7290 C CB  . GLU B 1 375 ? -1.03059  -2.69810  -34.67404 1.000 42.84993  ? 374 GLU B CB  1 
ATOM   7291 C CG  . GLU B 1 375 ? -2.20735  -2.22039  -35.46981 1.000 44.17459  ? 374 GLU B CG  1 
ATOM   7292 C CD  . GLU B 1 375 ? -1.76260  -1.51173  -36.73338 1.000 47.82127  ? 374 GLU B CD  1 
ATOM   7293 O OE1 . GLU B 1 375 ? -1.19616  -2.18480  -37.62243 1.000 43.18309  ? 374 GLU B OE1 1 
ATOM   7294 O OE2 . GLU B 1 375 ? -1.95317  -0.27536  -36.82622 1.000 49.69911  ? 374 GLU B OE2 1 
ATOM   7295 N N   . SER B 1 376 ? 0.65451   -4.22408  -32.31468 1.000 42.28177  ? 375 SER B N   1 
ATOM   7296 C CA  . SER B 1 376 ? 1.81533   -4.01247  -31.46663 1.000 43.31525  ? 375 SER B CA  1 
ATOM   7297 C C   . SER B 1 376 ? 2.82767   -3.10642  -32.17053 1.000 49.49793  ? 375 SER B C   1 
ATOM   7298 O O   . SER B 1 376 ? 3.04179   -3.22800  -33.38008 1.000 51.29035  ? 375 SER B O   1 
ATOM   7299 C CB  . SER B 1 376 ? 2.47905   -5.33929  -31.10984 1.000 42.51946  ? 375 SER B CB  1 
ATOM   7300 O OG  . SER B 1 376 ? 3.78321   -5.12840  -30.57443 1.000 41.54171  ? 375 SER B OG  1 
ATOM   7301 N N   . PRO B 1 377 ? 3.48942   -2.21297  -31.43154 1.000 50.62350  ? 376 PRO B N   1 
ATOM   7302 C CA  . PRO B 1 377 ? 4.51222   -1.35960  -32.04427 1.000 47.85635  ? 376 PRO B CA  1 
ATOM   7303 C C   . PRO B 1 377 ? 5.84064   -2.04883  -32.26762 1.000 45.23233  ? 376 PRO B C   1 
ATOM   7304 O O   . PRO B 1 377 ? 6.70732   -1.47408  -32.92918 1.000 45.46022  ? 376 PRO B O   1 
ATOM   7305 C CB  . PRO B 1 377 ? 4.67832   -0.23187  -31.02268 1.000 43.77648  ? 376 PRO B CB  1 
ATOM   7306 C CG  . PRO B 1 377 ? 3.87837   -0.64429  -29.81308 1.000 47.09229  ? 376 PRO B CG  1 
ATOM   7307 C CD  . PRO B 1 377 ? 3.47149   -2.05736  -29.97405 1.000 45.34642  ? 376 PRO B CD  1 
ATOM   7308 N N   . VAL B 1 378 ? 6.03202   -3.25361  -31.74173 1.000 50.64469  ? 377 VAL B N   1 
ATOM   7309 C CA  . VAL B 1 378 ? 7.37442   -3.81693  -31.65584 1.000 49.37585  ? 377 VAL B CA  1 
ATOM   7310 C C   . VAL B 1 378 ? 7.95602   -4.07810  -33.04358 1.000 53.57945  ? 377 VAL B C   1 
ATOM   7311 O O   . VAL B 1 378 ? 9.13577   -3.80205  -33.28483 1.000 49.88475  ? 377 VAL B O   1 
ATOM   7312 C CB  . VAL B 1 378 ? 7.33906   -5.08506  -30.78652 1.000 47.35605  ? 377 VAL B CB  1 
ATOM   7313 C CG1 . VAL B 1 378 ? 8.65886   -5.80858  -30.81708 1.000 42.20101  ? 377 VAL B CG1 1 
ATOM   7314 C CG2 . VAL B 1 378 ? 6.96568   -4.70550  -29.37279 1.000 47.80272  ? 377 VAL B CG2 1 
ATOM   7315 N N   . SER B 1 379 ? 7.14354   -4.58988  -33.98548 1.000 55.71466  ? 378 SER B N   1 
ATOM   7316 C CA  . SER B 1 379 ? 7.64253   -4.93645  -35.32417 1.000 53.79770  ? 378 SER B CA  1 
ATOM   7317 C C   . SER B 1 379 ? 8.09017   -3.73138  -36.15416 1.000 54.61887  ? 378 SER B C   1 
ATOM   7318 O O   . SER B 1 379 ? 8.68545   -3.92514  -37.21652 1.000 56.28280  ? 378 SER B O   1 
ATOM   7319 C CB  . SER B 1 379 ? 6.57849   -5.69359  -36.11964 1.000 50.61539  ? 378 SER B CB  1 
ATOM   7320 O OG  . SER B 1 379 ? 5.52919   -4.81458  -36.50088 1.000 59.83666  ? 378 SER B OG  1 
ATOM   7321 N N   . ARG B 1 380 ? 7.82443   -2.50525  -35.71310 1.000 53.29010  ? 379 ARG B N   1 
ATOM   7322 C CA  . ARG B 1 380 ? 8.16811   -1.30825  -36.46502 1.000 48.89071  ? 379 ARG B CA  1 
ATOM   7323 C C   . ARG B 1 380 ? 9.32310   -0.53003  -35.85475 1.000 55.58508  ? 379 ARG B C   1 
ATOM   7324 O O   . ARG B 1 380 ? 9.41923   0.68201   -36.07100 1.000 60.88852  ? 379 ARG B O   1 
ATOM   7325 C CB  . ARG B 1 380 ? 6.96185   -0.38719  -36.55449 1.000 58.28116  ? 379 ARG B CB  1 
ATOM   7326 C CG  . ARG B 1 380 ? 5.65775   -1.09272  -36.48998 1.000 59.17017  ? 379 ARG B CG  1 
ATOM   7327 C CD  . ARG B 1 380 ? 4.65258   -0.22502  -37.15482 1.000 60.55052  ? 379 ARG B CD  1 
ATOM   7328 N NE  . ARG B 1 380 ? 3.30244   -0.67528  -36.87722 1.000 62.72220  ? 379 ARG B NE  1 
ATOM   7329 C CZ  . ARG B 1 380 ? 2.22076   0.00148   -37.22703 1.000 64.23953  ? 379 ARG B CZ  1 
ATOM   7330 N NH1 . ARG B 1 380 ? 2.30654   1.19919   -37.78660 1.000 58.10964  ? 379 ARG B NH1 1 
ATOM   7331 N NH2 . ARG B 1 380 ? 1.02458   -0.53623  -37.01283 1.000 67.41621  ? 379 ARG B NH2 1 
ATOM   7332 N N   . VAL B 1 381 ? 10.18157  -1.17515  -35.07246 1.000 53.30448  ? 380 VAL B N   1 
ATOM   7333 C CA  . VAL B 1 381 ? 11.31078  -0.48516  -34.46479 1.000 53.34216  ? 380 VAL B CA  1 
ATOM   7334 C C   . VAL B 1 381 ? 12.56831  -1.32253  -34.64114 1.000 54.31260  ? 380 VAL B C   1 
ATOM   7335 O O   . VAL B 1 381 ? 12.51989  -2.55531  -34.69186 1.000 56.72866  ? 380 VAL B O   1 
ATOM   7336 C CB  . VAL B 1 381 ? 11.06415  -0.15626  -32.97404 1.000 53.23090  ? 380 VAL B CB  1 
ATOM   7337 C CG1 . VAL B 1 381 ? 10.06047  0.98420   -32.84753 1.000 54.28726  ? 380 VAL B CG1 1 
ATOM   7338 C CG2 . VAL B 1 381 ? 10.55746  -1.35683  -32.24052 1.000 48.63605  ? 380 VAL B CG2 1 
ATOM   7339 N N   . ALA B 1 382 ? 13.70291  -0.63736  -34.73954 1.000 55.08862  ? 381 ALA B N   1 
ATOM   7340 C CA  . ALA B 1 382 ? 14.96882  -1.28571  -35.04278 1.000 52.42219  ? 381 ALA B CA  1 
ATOM   7341 C C   . ALA B 1 382 ? 15.54837  -1.97971  -33.81399 1.000 53.86488  ? 381 ALA B C   1 
ATOM   7342 O O   . ALA B 1 382 ? 15.37637  -1.52228  -32.68100 1.000 60.11622  ? 381 ALA B O   1 
ATOM   7343 C CB  . ALA B 1 382 ? 15.96355  -0.25903  -35.57422 1.000 49.58773  ? 381 ALA B CB  1 
ATOM   7344 N N   . GLU B 1 383 ? 16.27558  -3.07843  -34.05651 1.000 48.68324  ? 382 GLU B N   1 
ATOM   7345 C CA  . GLU B 1 383 ? 16.93659  -3.83584  -32.99259 1.000 56.54045  ? 382 GLU B CA  1 
ATOM   7346 C C   . GLU B 1 383 ? 17.78016  -2.97239  -32.05198 1.000 57.21848  ? 382 GLU B C   1 
ATOM   7347 O O   . GLU B 1 383 ? 18.13237  -3.43147  -30.96158 1.000 59.78581  ? 382 GLU B O   1 
ATOM   7348 C CB  . GLU B 1 383 ? 17.82353  -4.92741  -33.60657 1.000 57.66022  ? 382 GLU B CB  1 
ATOM   7349 N N   . HIS B 1 384 ? 18.11331  -1.74399  -32.44630 1.000 56.85992  ? 383 HIS B N   1 
ATOM   7350 C CA  . HIS B 1 384 ? 18.87764  -0.80836  -31.63391 1.000 50.21496  ? 383 HIS B CA  1 
ATOM   7351 C C   . HIS B 1 384 ? 18.05529  0.37908   -31.14919 1.000 50.45514  ? 383 HIS B C   1 
ATOM   7352 O O   . HIS B 1 384 ? 18.58677  1.22729   -30.42828 1.000 58.00664  ? 383 HIS B O   1 
ATOM   7353 C CB  . HIS B 1 384 ? 20.05430  -0.27370  -32.44017 1.000 52.13979  ? 383 HIS B CB  1 
ATOM   7354 C CG  . HIS B 1 384 ? 19.61538  0.58257   -33.57887 1.000 54.98468  ? 383 HIS B CG  1 
ATOM   7355 N ND1 . HIS B 1 384 ? 19.56425  1.95805   -33.50144 1.000 58.41546  ? 383 HIS B ND1 1 
ATOM   7356 C CD2 . HIS B 1 384 ? 19.13037  0.25496   -34.79815 1.000 51.88363  ? 383 HIS B CD2 1 
ATOM   7357 C CE1 . HIS B 1 384 ? 19.09908  2.44426   -34.63755 1.000 52.11338  ? 383 HIS B CE1 1 
ATOM   7358 N NE2 . HIS B 1 384 ? 18.82502  1.43064   -35.43904 1.000 55.69953  ? 383 HIS B NE2 1 
ATOM   7359 N N   . GLU B 1 385 ? 16.79957  0.50109   -31.55513 1.000 48.44174  ? 384 GLU B N   1 
ATOM   7360 C CA  . GLU B 1 385 ? 15.96584  1.53678   -30.97073 1.000 46.55676  ? 384 GLU B CA  1 
ATOM   7361 C C   . GLU B 1 385 ? 15.35176  1.01944   -29.67300 1.000 41.81115  ? 384 GLU B C   1 
ATOM   7362 O O   . GLU B 1 385 ? 15.34410  -0.18357  -29.40142 1.000 42.80867  ? 384 GLU B O   1 
ATOM   7363 C CB  . GLU B 1 385 ? 14.88229  1.98260   -31.95822 1.000 51.34737  ? 384 GLU B CB  1 
ATOM   7364 C CG  . GLU B 1 385 ? 15.42791  2.75220   -33.16925 1.000 52.52502  ? 384 GLU B CG  1 
ATOM   7365 C CD  . GLU B 1 385 ? 14.40871  2.94190   -34.28329 1.000 55.46247  ? 384 GLU B CD  1 
ATOM   7366 O OE1 . GLU B 1 385 ? 13.56063  2.05288   -34.49494 1.000 56.52603  ? 384 GLU B OE1 1 
ATOM   7367 O OE2 . GLU B 1 385 ? 14.45038  3.99402   -34.95374 1.000 64.10319  ? 384 GLU B OE2 1 
ATOM   7368 N N   . GLN B 1 386 ? 14.84526  1.94884   -28.86167 1.000 43.51268  ? 385 GLN B N   1 
ATOM   7369 C CA  . GLN B 1 386 ? 14.30274  1.65348   -27.53426 1.000 42.31248  ? 385 GLN B CA  1 
ATOM   7370 C C   . GLN B 1 386 ? 12.89939  2.24204   -27.43114 1.000 41.91713  ? 385 GLN B C   1 
ATOM   7371 O O   . GLN B 1 386 ? 12.72029  3.44194   -27.65288 1.000 49.08577  ? 385 GLN B O   1 
ATOM   7372 C CB  . GLN B 1 386 ? 15.22730  2.22669   -26.44796 1.000 37.52898  ? 385 GLN B CB  1 
ATOM   7373 C CG  . GLN B 1 386 ? 14.62283  2.40649   -25.07461 1.000 39.86737  ? 385 GLN B CG  1 
ATOM   7374 C CD  . GLN B 1 386 ? 15.60629  3.02268   -24.07180 1.000 52.01421  ? 385 GLN B CD  1 
ATOM   7375 O OE1 . GLN B 1 386 ? 16.31806  3.98459   -24.38202 1.000 56.91236  ? 385 GLN B OE1 1 
ATOM   7376 N NE2 . GLN B 1 386 ? 15.64270  2.46851   -22.86110 1.000 51.81409  ? 385 GLN B NE2 1 
ATOM   7377 N N   . LEU B 1 387 ? 11.90405  1.41019   -27.11098 1.000 33.44221  ? 386 LEU B N   1 
ATOM   7378 C CA  . LEU B 1 387 ? 10.52543  1.87493   -26.95052 1.000 35.92043  ? 386 LEU B CA  1 
ATOM   7379 C C   . LEU B 1 387 ? 10.22853  2.24028   -25.49334 1.000 42.36608  ? 386 LEU B C   1 
ATOM   7380 O O   . LEU B 1 387 ? 10.47955  1.44433   -24.58351 1.000 44.83503  ? 386 LEU B O   1 
ATOM   7381 C CB  . LEU B 1 387 ? 9.54671   0.79738   -27.41056 1.000 35.88198  ? 386 LEU B CB  1 
ATOM   7382 C CG  . LEU B 1 387 ? 9.24705   0.61182   -28.89893 1.000 40.39639  ? 386 LEU B CG  1 
ATOM   7383 C CD1 . LEU B 1 387 ? 8.20991   -0.47316  -29.03781 1.000 40.76461  ? 386 LEU B CD1 1 
ATOM   7384 C CD2 . LEU B 1 387 ? 8.77747   1.90200   -29.56991 1.000 38.07041  ? 386 LEU B CD2 1 
ATOM   7385 N N   . THR B 1 388 ? 9.66522   3.42323   -25.26374 1.000 38.97289  ? 387 THR B N   1 
ATOM   7386 C CA  . THR B 1 388 ? 9.30541   3.76582   -23.89504 1.000 42.35205  ? 387 THR B CA  1 
ATOM   7387 C C   . THR B 1 388 ? 8.03919   4.60890   -23.82675 1.000 44.54701  ? 387 THR B C   1 
ATOM   7388 O O   . THR B 1 388 ? 7.78666   5.45715   -24.68880 1.000 45.40784  ? 387 THR B O   1 
ATOM   7389 C CB  . THR B 1 388 ? 10.42694  4.51593   -23.17851 1.000 49.86770  ? 387 THR B CB  1 
ATOM   7390 O OG1 . THR B 1 388 ? 9.90013   5.05667   -21.95612 1.000 50.82563  ? 387 THR B OG1 1 
ATOM   7391 C CG2 . THR B 1 388 ? 10.99000  5.65006   -24.05187 1.000 45.37937  ? 387 THR B CG2 1 
ATOM   7392 N N   . THR B 1 389 ? 7.25123   4.36921   -22.78267 1.000 44.95494  ? 388 THR B N   1 
ATOM   7393 C CA  . THR B 1 389 ? 6.10702   5.22641   -22.52380 1.000 45.11766  ? 388 THR B CA  1 
ATOM   7394 C C   . THR B 1 389 ? 6.57432   6.66035   -22.34791 1.000 42.33057  ? 388 THR B C   1 
ATOM   7395 O O   . THR B 1 389 ? 7.55935   6.92338   -21.65807 1.000 44.38711  ? 388 THR B O   1 
ATOM   7396 C CB  . THR B 1 389 ? 5.35015   4.77004   -21.27612 1.000 41.61204  ? 388 THR B CB  1 
ATOM   7397 O OG1 . THR B 1 389 ? 4.40837   5.78156   -20.92539 1.000 41.22672  ? 388 THR B OG1 1 
ATOM   7398 C CG2 . THR B 1 389 ? 6.28715   4.55136   -20.10914 1.000 38.89793  ? 388 THR B CG2 1 
ATOM   7399 N N   . MET B 1 390 ? 5.86549   7.59583   -22.98106 1.000 42.59124  ? 389 MET B N   1 
ATOM   7400 C CA  . MET B 1 390 ? 6.22133   8.99725   -22.81549 1.000 39.72550  ? 389 MET B CA  1 
ATOM   7401 C C   . MET B 1 390 ? 6.14773   9.42265   -21.34716 1.000 43.98550  ? 389 MET B C   1 
ATOM   7402 O O   . MET B 1 390 ? 6.76880   10.42119  -20.96438 1.000 45.97840  ? 389 MET B O   1 
ATOM   7403 C CB  . MET B 1 390 ? 5.33034   9.89254   -23.69409 1.000 35.63893  ? 389 MET B CB  1 
ATOM   7404 C CG  . MET B 1 390 ? 5.90710   11.31017  -23.87711 1.000 41.97989  ? 389 MET B CG  1 
ATOM   7405 S SD  . MET B 1 390 ? 4.91913   12.63684  -24.63233 1.000 47.06496  ? 389 MET B SD  1 
ATOM   7406 C CE  . MET B 1 390 ? 3.37575   12.61951  -23.71217 1.000 42.62754  ? 389 MET B CE  1 
ATOM   7407 N N   . ALA B 1 391 ? 5.43123   8.67508   -20.50306 1.000 44.92168  ? 390 ALA B N   1 
ATOM   7408 C CA  . ALA B 1 391 ? 5.35598   9.03585   -19.09191 1.000 40.06387  ? 390 ALA B CA  1 
ATOM   7409 C C   . ALA B 1 391 ? 6.71362   8.92690   -18.40505 1.000 43.19504  ? 390 ALA B C   1 
ATOM   7410 O O   . ALA B 1 391 ? 6.92882   9.56874   -17.36988 1.000 40.21372  ? 390 ALA B O   1 
ATOM   7411 C CB  . ALA B 1 391 ? 4.31859   8.16151   -18.38664 1.000 36.49706  ? 390 ALA B CB  1 
ATOM   7412 N N   . ALA B 1 392 ? 7.64085   8.14762   -18.97455 1.000 44.97903  ? 391 ALA B N   1 
ATOM   7413 C CA  . ALA B 1 392 ? 8.97869   8.01977   -18.40558 1.000 40.69279  ? 391 ALA B CA  1 
ATOM   7414 C C   . ALA B 1 392 ? 9.68721   9.36117   -18.26957 1.000 45.41551  ? 391 ALA B C   1 
ATOM   7415 O O   . ALA B 1 392 ? 10.60424  9.47318   -17.45049 1.000 50.25659  ? 391 ALA B O   1 
ATOM   7416 C CB  . ALA B 1 392 ? 9.82776   7.07187   -19.25789 1.000 40.00560  ? 391 ALA B CB  1 
ATOM   7417 N N   . LEU B 1 393 ? 9.29634   10.37545  -19.05757 1.000 44.21329  ? 392 LEU B N   1 
ATOM   7418 C CA  . LEU B 1 393 ? 9.89919   11.69885  -18.92317 1.000 42.46376  ? 392 LEU B CA  1 
ATOM   7419 C C   . LEU B 1 393 ? 9.53261   12.34238  -17.58729 1.000 49.82131  ? 392 LEU B C   1 
ATOM   7420 O O   . LEU B 1 393 ? 10.27920  13.18859  -17.06991 1.000 50.20544  ? 392 LEU B O   1 
ATOM   7421 C CB  . LEU B 1 393 ? 9.46775   12.59877  -20.08086 1.000 40.19220  ? 392 LEU B CB  1 
ATOM   7422 C CG  . LEU B 1 393 ? 9.73373   12.18027  -21.53405 1.000 43.04484  ? 392 LEU B CG  1 
ATOM   7423 C CD1 . LEU B 1 393 ? 9.81929   13.38557  -22.46346 1.000 40.86157  ? 392 LEU B CD1 1 
ATOM   7424 C CD2 . LEU B 1 393 ? 10.98341  11.34938  -21.65657 1.000 45.21042  ? 392 LEU B CD2 1 
ATOM   7425 N N   . LEU B 1 394 ? 8.40164   11.95403  -17.01029 1.000 42.45389  ? 393 LEU B N   1 
ATOM   7426 C CA  . LEU B 1 394 ? 8.01233   12.46668  -15.71134 1.000 37.59578  ? 393 LEU B CA  1 
ATOM   7427 C C   . LEU B 1 394 ? 8.44807   11.55537  -14.57195 1.000 44.82868  ? 393 LEU B C   1 
ATOM   7428 O O   . LEU B 1 394 ? 8.16015   11.85268  -13.40486 1.000 44.16151  ? 393 LEU B O   1 
ATOM   7429 C CB  . LEU B 1 394 ? 6.50633   12.68733  -15.67662 1.000 32.10862  ? 393 LEU B CB  1 
ATOM   7430 C CG  . LEU B 1 394 ? 6.07177   13.75750  -16.66807 1.000 32.42114  ? 393 LEU B CG  1 
ATOM   7431 C CD1 . LEU B 1 394 ? 4.74995   14.34769  -16.26661 1.000 34.83859  ? 393 LEU B CD1 1 
ATOM   7432 C CD2 . LEU B 1 394 ? 7.10840   14.83141  -16.72884 1.000 40.86861  ? 393 LEU B CD2 1 
ATOM   7433 N N   . HIS B 1 395 ? 9.17948   10.48964  -14.87298 1.000 41.82782  ? 394 HIS B N   1 
ATOM   7434 C CA  . HIS B 1 395 ? 9.54432   9.52010   -13.85788 1.000 43.41825  ? 394 HIS B CA  1 
ATOM   7435 C C   . HIS B 1 395 ? 10.67771  10.01175  -12.96439 1.000 50.29547  ? 394 HIS B C   1 
ATOM   7436 O O   . HIS B 1 395 ? 11.59304  10.70584  -13.41408 1.000 56.48446  ? 394 HIS B O   1 
ATOM   7437 C CB  . HIS B 1 395 ? 9.96943   8.21536   -14.49988 1.000 46.60850  ? 394 HIS B CB  1 
ATOM   7438 C CG  . HIS B 1 395 ? 10.10535  7.11227   -13.51536 1.000 48.11938  ? 394 HIS B CG  1 
ATOM   7439 N ND1 . HIS B 1 395 ? 9.12763   6.84252   -12.58277 1.000 43.55299  ? 394 HIS B ND1 1 
ATOM   7440 C CD2 . HIS B 1 395 ? 11.11077  6.23607   -13.28330 1.000 48.27350  ? 394 HIS B CD2 1 
ATOM   7441 C CE1 . HIS B 1 395 ? 9.52167   5.83434   -11.82393 1.000 50.72594  ? 394 HIS B CE1 1 
ATOM   7442 N NE2 . HIS B 1 395 ? 10.72134  5.44909   -12.22534 1.000 51.28207  ? 394 HIS B NE2 1 
ATOM   7443 N N   . ILE B 1 396 ? 10.61232  9.62593   -11.68426 1.000 49.29089  ? 395 ILE B N   1 
ATOM   7444 C CA  . ILE B 1 396 ? 11.68349  9.84703   -10.71442 1.000 46.70980  ? 395 ILE B CA  1 
ATOM   7445 C C   . ILE B 1 396 ? 11.86762  8.58569   -9.87081  1.000 49.95848  ? 395 ILE B C   1 
ATOM   7446 O O   . ILE B 1 396 ? 10.88739  7.97323   -9.43237  1.000 53.43116  ? 395 ILE B O   1 
ATOM   7447 C CB  . ILE B 1 396 ? 11.38965  11.05719  -9.81277  1.000 43.79095  ? 395 ILE B CB  1 
ATOM   7448 C CG1 . ILE B 1 396 ? 11.09015  12.29106  -10.65706 1.000 43.48047  ? 395 ILE B CG1 1 
ATOM   7449 C CG2 . ILE B 1 396 ? 12.57469  11.33527  -8.93714  1.000 48.37714  ? 395 ILE B CG2 1 
ATOM   7450 C CD1 . ILE B 1 396 ? 10.05223  13.16973  -10.07317 1.000 39.65228  ? 395 ILE B CD1 1 
ATOM   7451 N N   . ASP B 1 397 ? 13.12240  8.19238   -9.63394  1.000 48.53274  ? 396 ASP B N   1 
ATOM   7452 C CA  . ASP B 1 397 ? 13.35634  6.97023   -8.87417  1.000 49.76781  ? 396 ASP B CA  1 
ATOM   7453 C C   . ASP B 1 397 ? 13.22912  7.22982   -7.36366  1.000 50.75344  ? 396 ASP B C   1 
ATOM   7454 O O   . ASP B 1 397 ? 12.92150  8.33846   -6.90863  1.000 45.06558  ? 396 ASP B O   1 
ATOM   7455 C CB  . ASP B 1 397 ? 14.70200  6.33292   -9.26069  1.000 47.80710  ? 396 ASP B CB  1 
ATOM   7456 C CG  . ASP B 1 397 ? 15.92429  7.15124   -8.83632  1.000 52.12731  ? 396 ASP B CG  1 
ATOM   7457 O OD1 . ASP B 1 397 ? 15.77765  8.25679   -8.26816  1.000 49.99562  ? 396 ASP B OD1 1 
ATOM   7458 O OD2 . ASP B 1 397 ? 17.05891  6.67408   -9.09113  1.000 53.20306  ? 396 ASP B OD2 1 
ATOM   7459 N N   . HIS B 1 398 ? 13.42872  6.16292   -6.57835  1.000 52.68093  ? 397 HIS B N   1 
ATOM   7460 C CA  . HIS B 1 398 ? 13.33511  6.23400   -5.12172  1.000 53.04994  ? 397 HIS B CA  1 
ATOM   7461 C C   . HIS B 1 398 ? 14.34859  7.19472   -4.52813  1.000 55.64516  ? 397 HIS B C   1 
ATOM   7462 O O   . HIS B 1 398 ? 14.13872  7.68720   -3.40791  1.000 56.45017  ? 397 HIS B O   1 
ATOM   7463 C CB  . HIS B 1 398 ? 13.55078  4.84643   -4.52451  1.000 49.72268  ? 397 HIS B CB  1 
ATOM   7464 C CG  . HIS B 1 398 ? 14.59182  4.05344   -5.24212  1.000 51.61396  ? 397 HIS B CG  1 
ATOM   7465 N ND1 . HIS B 1 398 ? 14.30640  3.28400   -6.35022  1.000 52.34656  ? 397 HIS B ND1 1 
ATOM   7466 C CD2 . HIS B 1 398 ? 15.92392  3.93836   -5.03660  1.000 51.31616  ? 397 HIS B CD2 1 
ATOM   7467 C CE1 . HIS B 1 398 ? 15.41389  2.71165   -6.78441  1.000 48.84489  ? 397 HIS B CE1 1 
ATOM   7468 N NE2 . HIS B 1 398 ? 16.40995  3.09157   -6.00483  1.000 52.55996  ? 397 HIS B NE2 1 
ATOM   7469 N N   . ASN B 1 399 ? 15.43284  7.46757   -5.26410  1.000 52.71372  ? 398 ASN B N   1 
ATOM   7470 C CA  . ASN B 1 399 ? 16.54126  8.31157   -4.84096  1.000 49.26236  ? 398 ASN B CA  1 
ATOM   7471 C C   . ASN B 1 399 ? 16.40138  9.76403   -5.27484  1.000 50.02709  ? 398 ASN B C   1 
ATOM   7472 O O   . ASN B 1 399 ? 17.31929  10.55165  -5.03991  1.000 55.28250  ? 398 ASN B O   1 
ATOM   7473 C CB  . ASN B 1 399 ? 17.85526  7.74810   -5.38620  1.000 45.37289  ? 398 ASN B CB  1 
ATOM   7474 C CG  . ASN B 1 399 ? 18.27694  6.48275   -4.67993  1.000 50.21252  ? 398 ASN B CG  1 
ATOM   7475 O OD1 . ASN B 1 399 ? 18.01316  6.30949   -3.49332  1.000 62.36726  ? 398 ASN B OD1 1 
ATOM   7476 N ND2 . ASN B 1 399 ? 18.93941  5.59325   -5.39854  1.000 48.73844  ? 398 ASN B ND2 1 
ATOM   7477 N N   . GLY B 1 400 ? 15.29884  10.14324  -5.91009  1.000 54.01670  ? 399 GLY B N   1 
ATOM   7478 C CA  . GLY B 1 400 ? 15.16213  11.50818  -6.38274  1.000 53.52122  ? 399 GLY B CA  1 
ATOM   7479 C C   . GLY B 1 400 ? 15.81517  11.81337  -7.71184  1.000 42.76837  ? 399 GLY B C   1 
ATOM   7480 O O   . GLY B 1 400 ? 15.98723  12.98556  -8.04453  1.000 43.74122  ? 399 GLY B O   1 
ATOM   7481 N N   . ILE B 1 401 ? 16.15108  10.79937  -8.50093  1.000 45.39664  ? 400 ILE B N   1 
ATOM   7482 C CA  . ILE B 1 401 ? 16.90723  10.97914  -9.73825  1.000 55.04059  ? 400 ILE B CA  1 
ATOM   7483 C C   . ILE B 1 401 ? 15.91674  11.00888  -10.90110 1.000 56.50023  ? 400 ILE B C   1 
ATOM   7484 O O   . ILE B 1 401 ? 15.27435  9.97894   -11.18085 1.000 52.83314  ? 400 ILE B O   1 
ATOM   7485 C CB  . ILE B 1 401 ? 17.94708  9.86437   -9.91918  1.000 54.59425  ? 400 ILE B CB  1 
ATOM   7486 C CG1 . ILE B 1 401 ? 19.00571  9.97049   -8.82283  1.000 57.11805  ? 400 ILE B CG1 1 
ATOM   7487 C CG2 . ILE B 1 401 ? 18.58804  9.92476   -11.30052 1.000 49.69739  ? 400 ILE B CG2 1 
ATOM   7488 C CD1 . ILE B 1 401 ? 19.26420  11.40685  -8.34751  1.000 51.61771  ? 400 ILE B CD1 1 
ATOM   7489 N N   . PRO B 1 402 ? 15.75663  12.13634  -11.59996 1.000 52.70698  ? 401 PRO B N   1 
ATOM   7490 C CA  . PRO B 1 402 ? 14.82303  12.16124  -12.73003 1.000 48.17499  ? 401 PRO B CA  1 
ATOM   7491 C C   . PRO B 1 402 ? 15.35377  11.32335  -13.88258 1.000 53.90802  ? 401 PRO B C   1 
ATOM   7492 O O   . PRO B 1 402 ? 16.49506  11.48770  -14.32608 1.000 54.75918  ? 401 PRO B O   1 
ATOM   7493 C CB  . PRO B 1 402 ? 14.71998  13.64533  -13.08860 1.000 43.88998  ? 401 PRO B CB  1 
ATOM   7494 C CG  . PRO B 1 402 ? 15.85554  14.28937  -12.44745 1.000 45.12881  ? 401 PRO B CG  1 
ATOM   7495 C CD  . PRO B 1 402 ? 16.25673  13.47714  -11.26699 1.000 50.97711  ? 401 PRO B CD  1 
ATOM   7496 N N   . LEU B 1 403 ? 14.51589  10.38390  -14.32880 1.000 51.41758  ? 402 LEU B N   1 
ATOM   7497 C CA  . LEU B 1 403 ? 14.88888  9.48043   -15.40361 1.000 44.92798  ? 402 LEU B CA  1 
ATOM   7498 C C   . LEU B 1 403 ? 15.06922  10.23499  -16.70990 1.000 55.95969  ? 402 LEU B C   1 
ATOM   7499 O O   . LEU B 1 403 ? 15.83395  9.79106   -17.58011 1.000 53.61750  ? 402 LEU B O   1 
ATOM   7500 C CB  . LEU B 1 403 ? 13.82521  8.39062   -15.55446 1.000 43.63296  ? 402 LEU B CB  1 
ATOM   7501 C CG  . LEU B 1 403 ? 13.89799  7.51781   -16.81104 1.000 45.07179  ? 402 LEU B CG  1 
ATOM   7502 C CD1 . LEU B 1 403 ? 15.14238  6.62720   -16.79249 1.000 45.44215  ? 402 LEU B CD1 1 
ATOM   7503 C CD2 . LEU B 1 403 ? 12.62580  6.71145   -17.01638 1.000 37.88603  ? 402 LEU B CD2 1 
ATOM   7504 N N   . ALA B 1 404 ? 14.37210  11.36749  -16.87421 1.000 50.48942  ? 403 ALA B N   1 
ATOM   7505 C CA  . ALA B 1 404 ? 14.55606  12.15208  -18.08769 1.000 49.52150  ? 403 ALA B CA  1 
ATOM   7506 C C   . ALA B 1 404 ? 16.02912  12.48903  -18.28487 1.000 48.07566  ? 403 ALA B C   1 
ATOM   7507 O O   . ALA B 1 404 ? 16.60327  12.21393  -19.34329 1.000 50.67302  ? 403 ALA B O   1 
ATOM   7508 C CB  . ALA B 1 404 ? 13.69817  13.41527  -18.04555 1.000 51.13121  ? 403 ALA B CB  1 
ATOM   7509 N N   . GLY B 1 405 ? 16.67679  13.01980  -17.24824 1.000 44.25444  ? 404 GLY B N   1 
ATOM   7510 C CA  . GLY B 1 405 ? 18.09081  13.34461  -17.34919 1.000 49.61008  ? 404 GLY B CA  1 
ATOM   7511 C C   . GLY B 1 405 ? 19.00728  12.15426  -17.58153 1.000 52.50127  ? 404 GLY B C   1 
ATOM   7512 O O   . GLY B 1 405 ? 20.15925  12.33741  -17.98141 1.000 51.04193  ? 404 GLY B O   1 
ATOM   7513 N N   . GLU B 1 406 ? 18.53502  10.93680  -17.33384 1.000 58.14467  ? 405 GLU B N   1 
ATOM   7514 C CA  . GLU B 1 406 ? 19.36963  9.77845   -17.62898 1.000 56.92882  ? 405 GLU B CA  1 
ATOM   7515 C C   . GLU B 1 406 ? 19.31206  9.42060   -19.10211 1.000 53.03848  ? 405 GLU B C   1 
ATOM   7516 O O   . GLU B 1 406 ? 20.31112  8.96613   -19.66088 1.000 59.01915  ? 405 GLU B O   1 
ATOM   7517 C CB  . GLU B 1 406 ? 18.93923  8.58718   -16.77452 1.000 61.91082  ? 405 GLU B CB  1 
ATOM   7518 C CG  . GLU B 1 406 ? 19.39139  8.67463   -15.31871 1.000 62.81717  ? 405 GLU B CG  1 
ATOM   7519 C CD  . GLU B 1 406 ? 20.89498  8.78059   -15.19101 1.000 65.86415  ? 405 GLU B CD  1 
ATOM   7520 O OE1 . GLU B 1 406 ? 21.58524  8.07999   -15.96207 1.000 73.26545  ? 405 GLU B OE1 1 
ATOM   7521 O OE2 . GLU B 1 406 ? 21.37827  9.56079   -14.33421 1.000 64.26310  ? 405 GLU B OE2 1 
ATOM   7522 N N   . PHE B 1 407 ? 18.15352  9.60209   -19.73946 1.000 54.05674  ? 406 PHE B N   1 
ATOM   7523 C CA  . PHE B 1 407 ? 18.09718  9.59452   -21.20013 1.000 53.38178  ? 406 PHE B CA  1 
ATOM   7524 C C   . PHE B 1 407 ? 18.98901  10.68142  -21.76787 1.000 53.56349  ? 406 PHE B C   1 
ATOM   7525 O O   . PHE B 1 407 ? 19.77599  10.44740  -22.69405 1.000 52.77763  ? 406 PHE B O   1 
ATOM   7526 C CB  . PHE B 1 407 ? 16.66916  9.83553   -21.67774 1.000 47.97941  ? 406 PHE B CB  1 
ATOM   7527 C CG  . PHE B 1 407 ? 15.75051  8.69832   -21.44040 1.000 48.58262  ? 406 PHE B CG  1 
ATOM   7528 C CD1 . PHE B 1 407 ? 16.14285  7.40188   -21.74016 1.000 47.73563  ? 406 PHE B CD1 1 
ATOM   7529 C CD2 . PHE B 1 407 ? 14.48114  8.92642   -20.92013 1.000 44.74789  ? 406 PHE B CD2 1 
ATOM   7530 C CE1 . PHE B 1 407 ? 15.28032  6.34992   -21.52960 1.000 50.02314  ? 406 PHE B CE1 1 
ATOM   7531 C CE2 . PHE B 1 407 ? 13.61586  7.88650   -20.70126 1.000 43.25736  ? 406 PHE B CE2 1 
ATOM   7532 C CZ  . PHE B 1 407 ? 14.01354  6.59084   -21.00471 1.000 45.75405  ? 406 PHE B CZ  1 
ATOM   7533 N N   . ILE B 1 408 ? 18.85735  11.88762  -21.21227 1.000 49.91519  ? 407 ILE B N   1 
ATOM   7534 C CA  . ILE B 1 408 ? 19.59221  13.04792  -21.68887 1.000 45.96640  ? 407 ILE B CA  1 
ATOM   7535 C C   . ILE B 1 408 ? 21.09309  12.81960  -21.57119 1.000 52.37356  ? 407 ILE B C   1 
ATOM   7536 O O   . ILE B 1 408 ? 21.84684  13.03374  -22.53014 1.000 55.28380  ? 407 ILE B O   1 
ATOM   7537 C CB  . ILE B 1 408 ? 19.12503  14.29436  -20.92693 1.000 41.05501  ? 407 ILE B CB  1 
ATOM   7538 C CG1 . ILE B 1 408 ? 17.67189  14.58485  -21.30863 1.000 45.00839  ? 407 ILE B CG1 1 
ATOM   7539 C CG2 . ILE B 1 408 ? 19.99198  15.46026  -21.24794 1.000 46.47108  ? 407 ILE B CG2 1 
ATOM   7540 C CD1 . ILE B 1 408 ? 17.05160  15.73161  -20.56364 1.000 47.34568  ? 407 ILE B CD1 1 
ATOM   7541 N N   . GLN B 1 409 ? 21.55025  12.34157  -20.41090 1.000 56.37274  ? 408 GLN B N   1 
ATOM   7542 C CA  . GLN B 1 409 ? 22.97788  12.06881  -20.25725 1.000 58.39371  ? 408 GLN B CA  1 
ATOM   7543 C C   . GLN B 1 409 ? 23.40465  10.88300  -21.11613 1.000 65.30078  ? 408 GLN B C   1 
ATOM   7544 O O   . GLN B 1 409 ? 24.46159  10.93171  -21.75442 1.000 72.49489  ? 408 GLN B O   1 
ATOM   7545 C CB  . GLN B 1 409 ? 23.31370  11.85316  -18.77284 1.000 64.21748  ? 408 GLN B CB  1 
ATOM   7546 C CG  . GLN B 1 409 ? 24.82019  11.81102  -18.37674 1.000 72.84101  ? 408 GLN B CG  1 
ATOM   7547 C CD  . GLN B 1 409 ? 25.46620  10.42329  -18.37094 1.000 82.50909  ? 408 GLN B CD  1 
ATOM   7548 O OE1 . GLN B 1 409 ? 25.32163  9.62582   -19.30228 1.000 80.26722  ? 408 GLN B OE1 1 
ATOM   7549 N NE2 . GLN B 1 409 ? 26.19294  10.13664  -17.29579 1.000 85.03324  ? 408 GLN B NE2 1 
ATOM   7550 N N   . LYS B 1 410 ? 22.58960  9.82844   -21.18259 1.000 62.66004  ? 409 LYS B N   1 
ATOM   7551 C CA  . LYS B 1 410 ? 22.94325  8.70422   -22.04066 1.000 58.93304  ? 409 LYS B CA  1 
ATOM   7552 C C   . LYS B 1 410 ? 23.03197  9.13167   -23.49547 1.000 53.85579  ? 409 LYS B C   1 
ATOM   7553 O O   . LYS B 1 410 ? 23.78091  8.53381   -24.27194 1.000 55.14772  ? 409 LYS B O   1 
ATOM   7554 C CB  . LYS B 1 410 ? 21.92510  7.57159   -21.88277 1.000 55.24989  ? 409 LYS B CB  1 
ATOM   7555 C CG  . LYS B 1 410 ? 22.51595  6.18251   -22.07801 1.000 55.42670  ? 409 LYS B CG  1 
ATOM   7556 C CD  . LYS B 1 410 ? 21.81724  5.42546   -23.20567 1.000 61.63794  ? 409 LYS B CD  1 
ATOM   7557 C CE  . LYS B 1 410 ? 20.32310  5.21041   -22.88832 1.000 62.29792  ? 409 LYS B CE  1 
ATOM   7558 N NZ  . LYS B 1 410 ? 19.69924  4.06197   -23.62153 1.000 55.00326  ? 409 LYS B NZ  1 
ATOM   7559 N N   . SER B 1 411 ? 22.28794  10.16666  -23.87735 1.000 51.08387  ? 410 SER B N   1 
ATOM   7560 C CA  . SER B 1 411 ? 22.18464  10.51147  -25.28803 1.000 56.22094  ? 410 SER B CA  1 
ATOM   7561 C C   . SER B 1 411 ? 23.47049  11.15425  -25.79212 1.000 58.26668  ? 410 SER B C   1 
ATOM   7562 O O   . SER B 1 411 ? 24.02461  10.74189  -26.81623 1.000 55.51119  ? 410 SER B O   1 
ATOM   7563 C CB  . SER B 1 411 ? 20.97528  11.42660  -25.51544 1.000 54.42446  ? 410 SER B CB  1 
ATOM   7564 O OG  . SER B 1 411 ? 21.33621  12.79285  -25.48026 1.000 51.61884  ? 410 SER B OG  1 
ATOM   7565 N N   . GLY B 1 412 ? 23.97934  12.14261  -25.07138 1.000 60.88384  ? 411 GLY B N   1 
ATOM   7566 C CA  . GLY B 1 412 ? 25.10346  12.93071  -25.51906 1.000 54.59777  ? 411 GLY B CA  1 
ATOM   7567 C C   . GLY B 1 412 ? 24.71528  14.32510  -25.93753 1.000 50.93842  ? 411 GLY B C   1 
ATOM   7568 O O   . GLY B 1 412 ? 25.56352  15.22476  -25.92001 1.000 50.74717  ? 411 GLY B O   1 
ATOM   7569 N N   . LEU B 1 413 ? 23.45146  14.53366  -26.28498 1.000 44.58521  ? 412 LEU B N   1 
ATOM   7570 C CA  . LEU B 1 413 ? 22.97058  15.86101  -26.61486 1.000 50.63674  ? 412 LEU B CA  1 
ATOM   7571 C C   . LEU B 1 413 ? 22.97880  16.78305  -25.37764 1.000 53.02046  ? 412 LEU B C   1 
ATOM   7572 O O   . LEU B 1 413 ? 23.22839  16.37129  -24.23908 1.000 48.08388  ? 412 LEU B O   1 
ATOM   7573 C CB  . LEU B 1 413 ? 21.57196  15.76340  -27.22941 1.000 53.96781  ? 412 LEU B CB  1 
ATOM   7574 C CG  . LEU B 1 413 ? 21.47221  15.16211  -28.64491 1.000 52.62222  ? 412 LEU B CG  1 
ATOM   7575 C CD1 . LEU B 1 413 ? 22.65357  15.59456  -29.46563 1.000 55.92405  ? 412 LEU B CD1 1 
ATOM   7576 C CD2 . LEU B 1 413 ? 21.36720  13.64895  -28.66909 1.000 48.44578  ? 412 LEU B CD2 1 
ATOM   7577 N N   . ALA B 1 414 ? 22.72975  18.06335  -25.62698 1.000 56.27437  ? 413 ALA B N   1 
ATOM   7578 C CA  . ALA B 1 414 ? 22.59126  19.05230  -24.57754 1.000 49.58014  ? 413 ALA B CA  1 
ATOM   7579 C C   . ALA B 1 414 ? 21.14173  19.08403  -24.11495 1.000 57.61364  ? 413 ALA B C   1 
ATOM   7580 O O   . ALA B 1 414 ? 20.27536  18.41079  -24.67021 1.000 59.15769  ? 413 ALA B O   1 
ATOM   7581 C CB  . ALA B 1 414 ? 23.03520  20.42380  -25.07798 1.000 50.76910  ? 413 ALA B CB  1 
ATOM   7582 N N   . ALA B 1 415 ? 20.86538  19.87921  -23.08432 1.000 62.97992  ? 414 ALA B N   1 
ATOM   7583 C CA  . ALA B 1 415 ? 19.48239  20.06311  -22.65942 1.000 66.14701  ? 414 ALA B CA  1 
ATOM   7584 C C   . ALA B 1 415 ? 18.62484  20.58201  -23.80723 1.000 66.61949  ? 414 ALA B C   1 
ATOM   7585 O O   . ALA B 1 415 ? 17.55243  20.03827  -24.09410 1.000 60.83654  ? 414 ALA B O   1 
ATOM   7586 C CB  . ALA B 1 415 ? 19.42256  21.02177  -21.47412 1.000 69.41764  ? 414 ALA B CB  1 
ATOM   7587 N N   . GLN B 1 416 ? 19.08515  21.63735  -24.47869 1.000 62.05560  ? 415 GLN B N   1 
ATOM   7588 C CA  . GLN B 1 416 ? 18.35349  22.14651  -25.63091 1.000 63.48963  ? 415 GLN B CA  1 
ATOM   7589 C C   . GLN B 1 416 ? 18.14877  21.06861  -26.68827 1.000 63.35967  ? 415 GLN B C   1 
ATOM   7590 O O   . GLN B 1 416 ? 17.02201  20.84103  -27.14422 1.000 61.76001  ? 415 GLN B O   1 
ATOM   7591 C CB  . GLN B 1 416 ? 19.08758  23.33276  -26.24094 1.000 69.35375  ? 415 GLN B CB  1 
ATOM   7592 C CG  . GLN B 1 416 ? 18.16223  24.34398  -26.85334 1.000 69.36457  ? 415 GLN B CG  1 
ATOM   7593 C CD  . GLN B 1 416 ? 17.75259  25.39570  -25.85302 1.000 80.80856  ? 415 GLN B CD  1 
ATOM   7594 O OE1 . GLN B 1 416 ? 17.56764  25.10359  -24.66635 1.000 79.59165  ? 415 GLN B OE1 1 
ATOM   7595 N NE2 . GLN B 1 416 ? 17.61682  26.63500  -26.31949 1.000 82.76123  ? 415 GLN B NE2 1 
ATOM   7596 N N   . GLU B 1 417 ? 19.22936  20.39391  -27.09596 1.000 61.55301  ? 416 GLU B N   1 
ATOM   7597 C CA  . GLU B 1 417 ? 19.14956  19.55437  -28.29166 1.000 64.41039  ? 416 GLU B CA  1 
ATOM   7598 C C   . GLU B 1 417 ? 18.20937  18.36722  -28.08771 1.000 66.00880  ? 416 GLU B C   1 
ATOM   7599 O O   . GLU B 1 417 ? 17.47488  17.97897  -29.00969 1.000 64.60478  ? 416 GLU B O   1 
ATOM   7600 C CB  . GLU B 1 417 ? 20.54603  19.08792  -28.71655 1.000 54.62416  ? 416 GLU B CB  1 
ATOM   7601 C CG  . GLU B 1 417 ? 20.60595  18.49350  -30.14321 1.000 63.14509  ? 416 GLU B CG  1 
ATOM   7602 C CD  . GLU B 1 417 ? 19.96559  19.37432  -31.24895 1.000 67.75877  ? 416 GLU B CD  1 
ATOM   7603 O OE1 . GLU B 1 417 ? 19.77415  20.59967  -31.03284 1.000 61.39428  ? 416 GLU B OE1 1 
ATOM   7604 O OE2 . GLU B 1 417 ? 19.65756  18.82586  -32.34523 1.000 62.49948  ? 416 GLU B OE2 1 
ATOM   7605 N N   . TRP B 1 418 ? 18.19694  17.79283  -26.88571 1.000 62.32167  ? 417 TRP B N   1 
ATOM   7606 C CA  . TRP B 1 418 ? 17.23191  16.74317  -26.58763 1.000 54.66254  ? 417 TRP B CA  1 
ATOM   7607 C C   . TRP B 1 418 ? 15.80065  17.28088  -26.64707 1.000 56.16210  ? 417 TRP B C   1 
ATOM   7608 O O   . TRP B 1 418 ? 14.92332  16.66782  -27.26842 1.000 56.97981  ? 417 TRP B O   1 
ATOM   7609 C CB  . TRP B 1 418 ? 17.55415  16.14716  -25.22547 1.000 48.94930  ? 417 TRP B CB  1 
ATOM   7610 C CG  . TRP B 1 418 ? 17.17239  14.73867  -25.04719 1.000 46.38479  ? 417 TRP B CG  1 
ATOM   7611 C CD1 . TRP B 1 418 ? 17.99038  13.64081  -25.13112 1.000 48.52241  ? 417 TRP B CD1 1 
ATOM   7612 C CD2 . TRP B 1 418 ? 15.88208  14.25606  -24.69779 1.000 44.10931  ? 417 TRP B CD2 1 
ATOM   7613 N NE1 . TRP B 1 418 ? 17.27036  12.49930  -24.87175 1.000 49.29571  ? 417 TRP B NE1 1 
ATOM   7614 C CE2 . TRP B 1 418 ? 15.97286  12.85180  -24.59852 1.000 47.92633  ? 417 TRP B CE2 1 
ATOM   7615 C CE3 . TRP B 1 418 ? 14.64907  14.87215  -24.47219 1.000 47.40294  ? 417 TRP B CE3 1 
ATOM   7616 C CZ2 . TRP B 1 418 ? 14.87367  12.05584  -24.28844 1.000 43.91504  ? 417 TRP B CZ2 1 
ATOM   7617 C CZ3 . TRP B 1 418 ? 13.55385  14.07867  -24.16054 1.000 47.94138  ? 417 TRP B CZ3 1 
ATOM   7618 C CH2 . TRP B 1 418 ? 13.67517  12.68624  -24.06995 1.000 42.20956  ? 417 TRP B CH2 1 
ATOM   7619 N N   . LEU B 1 419 ? 15.55169  18.44819  -26.03835 1.000 50.48156  ? 418 LEU B N   1 
ATOM   7620 C CA  . LEU B 1 419 ? 14.19440  18.98415  -26.02242 1.000 46.82331  ? 418 LEU B CA  1 
ATOM   7621 C C   . LEU B 1 419 ? 13.72092  19.30507  -27.42992 1.000 52.96899  ? 418 LEU B C   1 
ATOM   7622 O O   . LEU B 1 419 ? 12.57172  19.02022  -27.78861 1.000 52.29927  ? 418 LEU B O   1 
ATOM   7623 C CB  . LEU B 1 419 ? 14.10998  20.23096  -25.13943 1.000 42.19253  ? 418 LEU B CB  1 
ATOM   7624 C CG  . LEU B 1 419 ? 12.70770  20.85466  -25.00961 1.000 43.25459  ? 418 LEU B CG  1 
ATOM   7625 C CD1 . LEU B 1 419 ? 11.67737  19.86997  -24.48102 1.000 46.14119  ? 418 LEU B CD1 1 
ATOM   7626 C CD2 . LEU B 1 419 ? 12.69163  22.09738  -24.13908 1.000 47.90334  ? 418 LEU B CD2 1 
ATOM   7627 N N   . ALA B 1 420 ? 14.59798  19.88810  -28.24865 1.000 56.98554  ? 419 ALA B N   1 
ATOM   7628 C CA  . ALA B 1 420 ? 14.19111  20.29399  -29.58874 1.000 52.57534  ? 419 ALA B CA  1 
ATOM   7629 C C   . ALA B 1 420 ? 13.77868  19.09290  -30.41708 1.000 52.63690  ? 419 ALA B C   1 
ATOM   7630 O O   . ALA B 1 420 ? 12.79259  19.15369  -31.15840 1.000 53.12511  ? 419 ALA B O   1 
ATOM   7631 C CB  . ALA B 1 420 ? 15.31825  21.05239  -30.27784 1.000 49.52220  ? 419 ALA B CB  1 
ATOM   7632 N N   . ARG B 1 421 ? 14.51070  17.98422  -30.28149 1.000 52.81802  ? 420 ARG B N   1 
ATOM   7633 C CA  . ARG B 1 421 ? 14.20071  16.77393  -31.03674 1.000 52.43114  ? 420 ARG B CA  1 
ATOM   7634 C C   . ARG B 1 421 ? 12.95848  16.07610  -30.50932 1.000 53.72338  ? 420 ARG B C   1 
ATOM   7635 O O   . ARG B 1 421 ? 12.13575  15.57815  -31.28899 1.000 53.50995  ? 420 ARG B O   1 
ATOM   7636 C CB  . ARG B 1 421 ? 15.37278  15.81900  -30.97809 1.000 48.22441  ? 420 ARG B CB  1 
ATOM   7637 C CG  . ARG B 1 421 ? 16.59095  16.37080  -31.59584 1.000 48.91747  ? 420 ARG B CG  1 
ATOM   7638 C CD  . ARG B 1 421 ? 17.68074  15.45991  -31.26256 1.000 49.91052  ? 420 ARG B CD  1 
ATOM   7639 N NE  . ARG B 1 421 ? 18.91033  15.80825  -31.94407 1.000 53.90072  ? 420 ARG B NE  1 
ATOM   7640 C CZ  . ARG B 1 421 ? 19.87868  14.93552  -32.14985 1.000 53.53395  ? 420 ARG B CZ  1 
ATOM   7641 N NH1 . ARG B 1 421 ? 19.74690  13.66979  -31.78383 1.000 56.94293  ? 420 ARG B NH1 1 
ATOM   7642 N NH2 . ARG B 1 421 ? 21.00186  15.33995  -32.73023 1.000 49.29453  ? 420 ARG B NH2 1 
ATOM   7643 N N   . TYR B 1 422 ? 12.82875  15.98091  -29.19088 1.000 49.96417  ? 421 TYR B N   1 
ATOM   7644 C CA  . TYR B 1 422 ? 11.58959  15.46628  -28.64304 1.000 44.95412  ? 421 TYR B CA  1 
ATOM   7645 C C   . TYR B 1 422 ? 10.40772  16.31379  -29.09976 1.000 47.12638  ? 421 TYR B C   1 
ATOM   7646 O O   . TYR B 1 422 ? 9.33745   15.78260  -29.41335 1.000 47.81856  ? 421 TYR B O   1 
ATOM   7647 C CB  . TYR B 1 422 ? 11.68555  15.40979  -27.12545 1.000 45.64449  ? 421 TYR B CB  1 
ATOM   7648 C CG  . TYR B 1 422 ? 10.34689  15.35824  -26.43246 1.000 46.27035  ? 421 TYR B CG  1 
ATOM   7649 C CD1 . TYR B 1 422 ? 9.56601   14.21419  -26.47183 1.000 36.08847  ? 421 TYR B CD1 1 
ATOM   7650 C CD2 . TYR B 1 422 ? 9.87276   16.45600  -25.73131 1.000 46.87611  ? 421 TYR B CD2 1 
ATOM   7651 C CE1 . TYR B 1 422 ? 8.36516   14.16669  -25.83843 1.000 40.81738  ? 421 TYR B CE1 1 
ATOM   7652 C CE2 . TYR B 1 422 ? 8.66656   16.41706  -25.09222 1.000 48.60548  ? 421 TYR B CE2 1 
ATOM   7653 C CZ  . TYR B 1 422 ? 7.91220   15.27308  -25.15104 1.000 46.31835  ? 421 TYR B CZ  1 
ATOM   7654 O OH  . TYR B 1 422 ? 6.69610   15.24668  -24.50721 1.000 50.08414  ? 421 TYR B OH  1 
ATOM   7655 N N   . LEU B 1 423 ? 10.59100  17.63114  -29.18753 1.000 46.00508  ? 422 LEU B N   1 
ATOM   7656 C CA  . LEU B 1 423 ? 9.49293   18.48012  -29.63849 1.000 48.51594  ? 422 LEU B CA  1 
ATOM   7657 C C   . LEU B 1 423 ? 9.13342   18.22534  -31.10869 1.000 50.72764  ? 422 LEU B C   1 
ATOM   7658 O O   . LEU B 1 423 ? 7.96081   18.33996  -31.48783 1.000 46.65741  ? 422 LEU B O   1 
ATOM   7659 C CB  . LEU B 1 423 ? 9.84745   19.94943  -29.40462 1.000 51.45199  ? 422 LEU B CB  1 
ATOM   7660 C CG  . LEU B 1 423 ? 9.83165   20.43201  -27.95366 1.000 48.54240  ? 422 LEU B CG  1 
ATOM   7661 C CD1 . LEU B 1 423 ? 10.26438  21.90176  -27.82628 1.000 45.00509  ? 422 LEU B CD1 1 
ATOM   7662 C CD2 . LEU B 1 423 ? 8.44843   20.21198  -27.38318 1.000 45.44315  ? 422 LEU B CD2 1 
ATOM   7663 N N   . ARG B 1 424 ? 10.11207  17.87725  -31.95238 1.000 51.11206  ? 423 ARG B N   1 
ATOM   7664 C CA  . ARG B 1 424 ? 9.78906   17.55082  -33.33914 1.000 49.39042  ? 423 ARG B CA  1 
ATOM   7665 C C   . ARG B 1 424 ? 9.10698   16.19850  -33.43953 1.000 47.25207  ? 423 ARG B C   1 
ATOM   7666 O O   . ARG B 1 424 ? 8.15479   16.04070  -34.20981 1.000 48.10871  ? 423 ARG B O   1 
ATOM   7667 C CB  . ARG B 1 424 ? 11.04661  17.58572  -34.20339 1.000 51.11536  ? 423 ARG B CB  1 
ATOM   7668 C CG  . ARG B 1 424 ? 11.84209  18.85506  -34.00395 1.000 56.54759  ? 423 ARG B CG  1 
ATOM   7669 C CD  . ARG B 1 424 ? 12.67199  19.24315  -35.20509 1.000 57.16058  ? 423 ARG B CD  1 
ATOM   7670 N NE  . ARG B 1 424 ? 14.08814  18.98142  -34.95486 1.000 66.76462  ? 423 ARG B NE  1 
ATOM   7671 C CZ  . ARG B 1 424 ? 14.88181  19.76206  -34.22793 1.000 69.40418  ? 423 ARG B CZ  1 
ATOM   7672 N NH1 . ARG B 1 424 ? 14.42898  20.87465  -33.65919 1.000 66.00592  ? 423 ARG B NH1 1 
ATOM   7673 N NH2 . ARG B 1 424 ? 16.15755  19.41129  -34.05391 1.000 61.54199  ? 423 ARG B NH2 1 
ATOM   7674 N N   . ALA B 1 425 ? 9.55366   15.22237  -32.64314 1.000 45.53972  ? 424 ALA B N   1 
ATOM   7675 C CA  . ALA B 1 425 ? 8.98868   13.87907  -32.68763 1.000 43.20680  ? 424 ALA B CA  1 
ATOM   7676 C C   . ALA B 1 425 ? 7.56672   13.78166  -32.14380 1.000 43.40612  ? 424 ALA B C   1 
ATOM   7677 O O   . ALA B 1 425 ? 6.92292   12.75676  -32.36774 1.000 45.42281  ? 424 ALA B O   1 
ATOM   7678 C CB  . ALA B 1 425 ? 9.87825   12.90937  -31.91806 1.000 41.27387  ? 424 ALA B CB  1 
ATOM   7679 N N   . TYR B 1 426 ? 7.04899   14.79581  -31.45264 1.000 42.26926  ? 425 TYR B N   1 
ATOM   7680 C CA  . TYR B 1 426 ? 5.78244   14.61262  -30.74963 1.000 40.20333  ? 425 TYR B CA  1 
ATOM   7681 C C   . TYR B 1 426 ? 4.87123   15.83271  -30.83649 1.000 40.50380  ? 425 TYR B C   1 
ATOM   7682 O O   . TYR B 1 426 ? 3.66710   15.70547  -31.08172 1.000 36.10569  ? 425 TYR B O   1 
ATOM   7683 C CB  . TYR B 1 426 ? 6.06059   14.24312  -29.28069 1.000 37.50048  ? 425 TYR B CB  1 
ATOM   7684 C CG  . TYR B 1 426 ? 5.01153   14.69638  -28.27745 1.000 40.55314  ? 425 TYR B CG  1 
ATOM   7685 C CD1 . TYR B 1 426 ? 3.77148   14.07109  -28.19673 1.000 38.14297  ? 425 TYR B CD1 1 
ATOM   7686 C CD2 . TYR B 1 426 ? 5.27063   15.74464  -27.39447 1.000 43.21085  ? 425 TYR B CD2 1 
ATOM   7687 C CE1 . TYR B 1 426 ? 2.81664   14.48506  -27.27239 1.000 38.40828  ? 425 TYR B CE1 1 
ATOM   7688 C CE2 . TYR B 1 426 ? 4.32044   16.16478  -26.47485 1.000 42.98596  ? 425 TYR B CE2 1 
ATOM   7689 C CZ  . TYR B 1 426 ? 3.09654   15.52965  -26.41777 1.000 42.32421  ? 425 TYR B CZ  1 
ATOM   7690 O OH  . TYR B 1 426 ? 2.15685   15.94199  -25.49586 1.000 49.82201  ? 425 TYR B OH  1 
ATOM   7691 N N   . LEU B 1 427 ? 5.42671   17.02057  -30.60900 1.000 44.37405  ? 426 LEU B N   1 
ATOM   7692 C CA  . LEU B 1 427 ? 4.61629   18.22998  -30.66992 1.000 38.35612  ? 426 LEU B CA  1 
ATOM   7693 C C   . LEU B 1 427 ? 4.22988   18.54991  -32.10912 1.000 45.37699  ? 426 LEU B C   1 
ATOM   7694 O O   . LEU B 1 427 ? 3.07505   18.89301  -32.38905 1.000 45.34271  ? 426 LEU B O   1 
ATOM   7695 C CB  . LEU B 1 427 ? 5.37590   19.38820  -30.02653 1.000 32.77431  ? 426 LEU B CB  1 
ATOM   7696 C CG  . LEU B 1 427 ? 4.77453   20.78213  -30.14103 1.000 40.83765  ? 426 LEU B CG  1 
ATOM   7697 C CD1 . LEU B 1 427 ? 3.37233   20.88950  -29.52548 1.000 31.42139  ? 426 LEU B CD1 1 
ATOM   7698 C CD2 . LEU B 1 427 ? 5.72889   21.76231  -29.50645 1.000 46.06490  ? 426 LEU B CD2 1 
ATOM   7699 N N   . HIS B 1 428 ? 5.17232   18.41298  -33.04191 1.000 46.57970  ? 427 HIS B N   1 
ATOM   7700 C CA  . HIS B 1 428 ? 4.87513   18.74540  -34.43348 1.000 46.44254  ? 427 HIS B CA  1 
ATOM   7701 C C   . HIS B 1 428 ? 3.76984   17.86163  -35.01329 1.000 44.80038  ? 427 HIS B C   1 
ATOM   7702 O O   . HIS B 1 428 ? 2.77756   18.41181  -35.52218 1.000 45.80767  ? 427 HIS B O   1 
ATOM   7703 C CB  . HIS B 1 428 ? 6.17137   18.69795  -35.25955 1.000 46.15452  ? 427 HIS B CB  1 
ATOM   7704 C CG  . HIS B 1 428 ? 7.15006   19.79654  -34.94205 1.000 49.25096  ? 427 HIS B CG  1 
ATOM   7705 N ND1 . HIS B 1 428 ? 8.40704   19.86325  -35.51307 1.000 52.98725  ? 427 HIS B ND1 1 
ATOM   7706 C CD2 . HIS B 1 428 ? 7.05404   20.87416  -34.12665 1.000 43.80239  ? 427 HIS B CD2 1 
ATOM   7707 C CE1 . HIS B 1 428 ? 9.04199   20.92995  -35.06039 1.000 47.57423  ? 427 HIS B CE1 1 
ATOM   7708 N NE2 . HIS B 1 428 ? 8.24519   21.55694  -34.21340 1.000 48.30070  ? 427 HIS B NE2 1 
ATOM   7709 N N   . PRO B 1 429 ? 3.83755   16.52544  -34.94820 1.000 41.38189  ? 428 PRO B N   1 
ATOM   7710 C CA  . PRO B 1 429 ? 2.72448   15.72897  -35.50242 1.000 42.78093  ? 428 PRO B CA  1 
ATOM   7711 C C   . PRO B 1 429 ? 1.37000   16.02605  -34.87450 1.000 46.42233  ? 428 PRO B C   1 
ATOM   7712 O O   . PRO B 1 429 ? 0.35808   16.04147  -35.59084 1.000 49.55880  ? 428 PRO B O   1 
ATOM   7713 C CB  . PRO B 1 429 ? 3.16250   14.28145  -35.24778 1.000 43.22281  ? 428 PRO B CB  1 
ATOM   7714 C CG  . PRO B 1 429 ? 4.33785   14.35668  -34.34293 1.000 46.39973  ? 428 PRO B CG  1 
ATOM   7715 C CD  . PRO B 1 429 ? 4.97012   15.67535  -34.54622 1.000 44.34723  ? 428 PRO B CD  1 
ATOM   7716 N N   . ILE B 1 430 ? 1.31529   16.26450  -33.56109 1.000 42.99179  ? 429 ILE B N   1 
ATOM   7717 C CA  . ILE B 1 430 ? 0.06226   16.68552  -32.93399 1.000 42.51754  ? 429 ILE B CA  1 
ATOM   7718 C C   . ILE B 1 430 ? -0.45054  17.96251  -33.57869 1.000 47.11481  ? 429 ILE B C   1 
ATOM   7719 O O   . ILE B 1 430 ? -1.63773  18.07208  -33.91232 1.000 51.13970  ? 429 ILE B O   1 
ATOM   7720 C CB  . ILE B 1 430 ? 0.24057   16.88489  -31.41822 1.000 39.89764  ? 429 ILE B CB  1 
ATOM   7721 C CG1 . ILE B 1 430 ? 0.38088   15.54289  -30.68913 1.000 36.17191  ? 429 ILE B CG1 1 
ATOM   7722 C CG2 . ILE B 1 430 ? -0.93311  17.70954  -30.85978 1.000 30.52850  ? 429 ILE B CG2 1 
ATOM   7723 C CD1 . ILE B 1 430 ? -0.37753  14.38747  -31.33570 1.000 36.92247  ? 429 ILE B CD1 1 
ATOM   7724 N N   . ILE B 1 431 ? 0.42988   18.96613  -33.72082 1.000 47.10995  ? 430 ILE B N   1 
ATOM   7725 C CA  . ILE B 1 431 ? 0.03086   20.21873  -34.36023 1.000 48.17438  ? 430 ILE B CA  1 
ATOM   7726 C C   . ILE B 1 431 ? -0.43635  19.93958  -35.77236 1.000 44.03188  ? 430 ILE B C   1 
ATOM   7727 O O   . ILE B 1 431 ? -1.47476  20.44196  -36.21644 1.000 47.46704  ? 430 ILE B O   1 
ATOM   7728 C CB  . ILE B 1 431 ? 1.18558   21.24184  -34.37380 1.000 48.28601  ? 430 ILE B CB  1 
ATOM   7729 C CG1 . ILE B 1 431 ? 1.63272   21.62216  -32.97364 1.000 46.84263  ? 430 ILE B CG1 1 
ATOM   7730 C CG2 . ILE B 1 431 ? 0.75510   22.52874  -35.07795 1.000 41.58934  ? 430 ILE B CG2 1 
ATOM   7731 C CD1 . ILE B 1 431 ? 3.01947   22.22020  -32.96518 1.000 43.36900  ? 430 ILE B CD1 1 
ATOM   7732 N N   . TYR B 1 432 ? 0.32290   19.11803  -36.49198 1.000 41.44874  ? 431 TYR B N   1 
ATOM   7733 C CA  . TYR B 1 432 ? 0.03151   18.86623  -37.89346 1.000 42.74894  ? 431 TYR B CA  1 
ATOM   7734 C C   . TYR B 1 432 ? -1.31250  18.16706  -38.05672 1.000 49.98183  ? 431 TYR B C   1 
ATOM   7735 O O   . TYR B 1 432 ? -2.13638  18.56740  -38.88744 1.000 50.23578  ? 431 TYR B O   1 
ATOM   7736 C CB  . TYR B 1 432 ? 1.15842   18.04528  -38.50291 1.000 42.48929  ? 431 TYR B CB  1 
ATOM   7737 C CG  . TYR B 1 432 ? 0.94593   17.72742  -39.95132 1.000 47.16497  ? 431 TYR B CG  1 
ATOM   7738 C CD1 . TYR B 1 432 ? 0.94203   18.72717  -40.91994 1.000 45.51488  ? 431 TYR B CD1 1 
ATOM   7739 C CD2 . TYR B 1 432 ? 0.73425   16.41729  -40.35494 1.000 49.78994  ? 431 TYR B CD2 1 
ATOM   7740 C CE1 . TYR B 1 432 ? 0.74581   18.42039  -42.24934 1.000 42.13739  ? 431 TYR B CE1 1 
ATOM   7741 C CE2 . TYR B 1 432 ? 0.55295   16.10040  -41.67375 1.000 47.91952  ? 431 TYR B CE2 1 
ATOM   7742 C CZ  . TYR B 1 432 ? 0.55063   17.10297  -42.61770 1.000 44.17401  ? 431 TYR B CZ  1 
ATOM   7743 O OH  . TYR B 1 432 ? 0.34657   16.75866  -43.92472 1.000 41.90837  ? 431 TYR B OH  1 
ATOM   7744 N N   . LEU B 1 433 ? -1.56106  17.12501  -37.25821 1.000 49.06874  ? 432 LEU B N   1 
ATOM   7745 C CA  . LEU B 1 433 ? -2.85589  16.45523  -37.31563 1.000 46.69379  ? 432 LEU B CA  1 
ATOM   7746 C C   . LEU B 1 433 ? -4.00228  17.43675  -37.08878 1.000 42.51148  ? 432 LEU B C   1 
ATOM   7747 O O   . LEU B 1 433 ? -5.03102  17.36660  -37.76684 1.000 42.04563  ? 432 LEU B O   1 
ATOM   7748 C CB  . LEU B 1 433 ? -2.89856  15.32042  -36.29230 1.000 46.79323  ? 432 LEU B CB  1 
ATOM   7749 C CG  . LEU B 1 433 ? -2.04623  14.10869  -36.64456 1.000 45.53753  ? 432 LEU B CG  1 
ATOM   7750 C CD1 . LEU B 1 433 ? -2.20376  13.02314  -35.59163 1.000 45.30320  ? 432 LEU B CD1 1 
ATOM   7751 C CD2 . LEU B 1 433 ? -2.42087  13.58951  -38.02065 1.000 44.58499  ? 432 LEU B CD2 1 
ATOM   7752 N N   . LEU B 1 434 ? -3.83273  18.37243  -36.15427 1.000 46.54992  ? 433 LEU B N   1 
ATOM   7753 C CA  . LEU B 1 434 ? -4.92013  19.27198  -35.78102 1.000 50.41251  ? 433 LEU B CA  1 
ATOM   7754 C C   . LEU B 1 434 ? -5.12660  20.37760  -36.81322 1.000 50.24910  ? 433 LEU B C   1 
ATOM   7755 O O   . LEU B 1 434 ? -6.26383  20.74423  -37.12173 1.000 47.57777  ? 433 LEU B O   1 
ATOM   7756 C CB  . LEU B 1 434 ? -4.63722  19.87684  -34.40584 1.000 48.62915  ? 433 LEU B CB  1 
ATOM   7757 C CG  . LEU B 1 434 ? -5.72839  20.75532  -33.77271 1.000 51.83554  ? 433 LEU B CG  1 
ATOM   7758 C CD1 . LEU B 1 434 ? -7.13322  20.19079  -33.96533 1.000 47.09558  ? 433 LEU B CD1 1 
ATOM   7759 C CD2 . LEU B 1 434 ? -5.43634  20.98364  -32.29447 1.000 49.33942  ? 433 LEU B CD2 1 
ATOM   7760 N N   . TYR B 1 435 ? -4.04805  20.92986  -37.34521 1.000 46.94327  ? 434 TYR B N   1 
ATOM   7761 C CA  . TYR B 1 435 ? -4.17843  22.03466  -38.27616 1.000 47.67291  ? 434 TYR B CA  1 
ATOM   7762 C C   . TYR B 1 435 ? -4.36871  21.57557  -39.71201 1.000 46.96663  ? 434 TYR B C   1 
ATOM   7763 O O   . TYR B 1 435 ? -5.06201  22.24917  -40.47928 1.000 50.07477  ? 434 TYR B O   1 
ATOM   7764 C CB  . TYR B 1 435 ? -2.95205  22.94582  -38.16646 1.000 49.20130  ? 434 TYR B CB  1 
ATOM   7765 C CG  . TYR B 1 435 ? -3.03871  23.86339  -36.97345 1.000 52.20415  ? 434 TYR B CG  1 
ATOM   7766 C CD1 . TYR B 1 435 ? -2.78790  23.38464  -35.69073 1.000 54.19010  ? 434 TYR B CD1 1 
ATOM   7767 C CD2 . TYR B 1 435 ? -3.40096  25.19611  -37.12129 1.000 45.69684  ? 434 TYR B CD2 1 
ATOM   7768 C CE1 . TYR B 1 435 ? -2.87774  24.21075  -34.59656 1.000 51.02580  ? 434 TYR B CE1 1 
ATOM   7769 C CE2 . TYR B 1 435 ? -3.49930  26.02408  -36.03901 1.000 47.30115  ? 434 TYR B CE2 1 
ATOM   7770 C CZ  . TYR B 1 435 ? -3.23822  25.52749  -34.77561 1.000 52.23322  ? 434 TYR B CZ  1 
ATOM   7771 O OH  . TYR B 1 435 ? -3.33708  26.35026  -33.67875 1.000 55.85919  ? 434 TYR B OH  1 
ATOM   7772 N N   . ARG B 1 436 ? -3.77947  20.44936  -40.09887 1.000 41.49957  ? 435 ARG B N   1 
ATOM   7773 C CA  . ARG B 1 436 ? -3.88822  20.00709  -41.48190 1.000 47.26297  ? 435 ARG B CA  1 
ATOM   7774 C C   . ARG B 1 436 ? -5.14985  19.17791  -41.71580 1.000 48.97157  ? 435 ARG B C   1 
ATOM   7775 O O   . ARG B 1 436 ? -5.87491  19.40200  -42.69523 1.000 43.94551  ? 435 ARG B O   1 
ATOM   7776 C CB  . ARG B 1 436 ? -2.63517  19.21654  -41.87737 1.000 42.86627  ? 435 ARG B CB  1 
ATOM   7777 C CG  . ARG B 1 436 ? -2.79207  18.39822  -43.14297 1.000 44.57597  ? 435 ARG B CG  1 
ATOM   7778 C CD  . ARG B 1 436 ? -2.77070  19.28417  -44.38995 1.000 46.90778  ? 435 ARG B CD  1 
ATOM   7779 N NE  . ARG B 1 436 ? -2.93904  18.51017  -45.61682 1.000 48.79818  ? 435 ARG B NE  1 
ATOM   7780 C CZ  . ARG B 1 436 ? -4.07826  17.94570  -45.99598 1.000 43.05032  ? 435 ARG B CZ  1 
ATOM   7781 N NH1 . ARG B 1 436 ? -5.16794  18.01929  -45.25273 1.000 42.90768  ? 435 ARG B NH1 1 
ATOM   7782 N NH2 . ARG B 1 436 ? -4.12757  17.30308  -47.15529 1.000 43.51561  ? 435 ARG B NH2 1 
ATOM   7783 N N   . TYR B 1 437 ? -5.43031  18.23419  -40.81410 1.000 48.19756  ? 436 TYR B N   1 
ATOM   7784 C CA  . TYR B 1 437 ? -6.57346  17.34367  -40.93828 1.000 45.68768  ? 436 TYR B CA  1 
ATOM   7785 C C   . TYR B 1 437 ? -7.67117  17.61416  -39.91798 1.000 48.64725  ? 436 TYR B C   1 
ATOM   7786 O O   . TYR B 1 437 ? -8.72265  16.97501  -39.98835 1.000 55.68362  ? 436 TYR B O   1 
ATOM   7787 C CB  . TYR B 1 437 ? -6.12610  15.88397  -40.81289 1.000 43.68825  ? 436 TYR B CB  1 
ATOM   7788 C CG  . TYR B 1 437 ? -5.22283  15.38285  -41.92691 1.000 45.64779  ? 436 TYR B CG  1 
ATOM   7789 C CD1 . TYR B 1 437 ? -5.70236  15.20507  -43.21281 1.000 40.63415  ? 436 TYR B CD1 1 
ATOM   7790 C CD2 . TYR B 1 437 ? -3.89896  15.05124  -41.67507 1.000 42.63591  ? 436 TYR B CD2 1 
ATOM   7791 C CE1 . TYR B 1 437 ? -4.88158  14.74832  -44.21608 1.000 44.03582  ? 436 TYR B CE1 1 
ATOM   7792 C CE2 . TYR B 1 437 ? -3.08079  14.57855  -42.66700 1.000 40.73308  ? 436 TYR B CE2 1 
ATOM   7793 C CZ  . TYR B 1 437 ? -3.57085  14.43296  -43.93717 1.000 46.12504  ? 436 TYR B CZ  1 
ATOM   7794 O OH  . TYR B 1 437 ? -2.74309  13.96849  -44.93372 1.000 45.45424  ? 436 TYR B OH  1 
ATOM   7795 N N   . GLU B 1 438 ? -7.46468  18.52591  -38.96954 1.000 47.05893  ? 437 GLU B N   1 
ATOM   7796 C CA  . GLU B 1 438 ? -8.48163  18.85567  -37.96439 1.000 51.30593  ? 437 GLU B CA  1 
ATOM   7797 C C   . GLU B 1 438 ? -8.87719  17.63520  -37.11659 1.000 53.64787  ? 437 GLU B C   1 
ATOM   7798 O O   . GLU B 1 438 ? -10.06023 17.36453  -36.88328 1.000 49.57422  ? 437 GLU B O   1 
ATOM   7799 C CB  . GLU B 1 438 ? -9.69775  19.50487  -38.63118 1.000 51.83960  ? 437 GLU B CB  1 
ATOM   7800 C CG  . GLU B 1 438 ? -9.30040  20.45099  -39.76958 1.000 56.45375  ? 437 GLU B CG  1 
ATOM   7801 C CD  . GLU B 1 438 ? -10.21734 21.65034  -39.92246 1.000 59.70096  ? 437 GLU B CD  1 
ATOM   7802 O OE1 . GLU B 1 438 ? -10.80689 22.07338  -38.91069 1.000 63.01007  ? 437 GLU B OE1 1 
ATOM   7803 O OE2 . GLU B 1 438 ? -10.33886 22.17769  -41.05134 1.000 59.72879  ? 437 GLU B OE2 1 
ATOM   7804 N N   . PHE B 1 439 ? -7.86087  16.90416  -36.63891 1.000 52.14173  ? 438 PHE B N   1 
ATOM   7805 C CA  . PHE B 1 439 ? -8.01947  15.81909  -35.67387 1.000 46.30442  ? 438 PHE B CA  1 
ATOM   7806 C C   . PHE B 1 439 ? -7.37866  16.20620  -34.35122 1.000 50.38163  ? 438 PHE B C   1 
ATOM   7807 O O   . PHE B 1 439 ? -6.18667  16.54114  -34.30697 1.000 49.73597  ? 438 PHE B O   1 
ATOM   7808 C CB  . PHE B 1 439 ? -7.35194  14.51979  -36.12557 1.000 47.00797  ? 438 PHE B CB  1 
ATOM   7809 C CG  . PHE B 1 439 ? -7.86297  13.97214  -37.40228 1.000 47.48144  ? 438 PHE B CG  1 
ATOM   7810 C CD1 . PHE B 1 439 ? -9.18081  14.14295  -37.76914 1.000 48.94734  ? 438 PHE B CD1 1 
ATOM   7811 C CD2 . PHE B 1 439 ? -7.01116  13.26457  -38.24029 1.000 44.51433  ? 438 PHE B CD2 1 
ATOM   7812 C CE1 . PHE B 1 439 ? -9.64234  13.62525  -38.95719 1.000 46.74492  ? 438 PHE B CE1 1 
ATOM   7813 C CE2 . PHE B 1 439 ? -7.46091  12.74533  -39.41734 1.000 41.59468  ? 438 PHE B CE2 1 
ATOM   7814 C CZ  . PHE B 1 439 ? -8.78177  12.92630  -39.78302 1.000 44.72500  ? 438 PHE B CZ  1 
ATOM   7815 N N   . LYS B 1 440 ? -8.15669  16.11491  -33.27746 1.000 54.55446  ? 439 LYS B N   1 
ATOM   7816 C CA  . LYS B 1 440 ? -7.64846  16.11592  -31.91286 1.000 53.33583  ? 439 LYS B CA  1 
ATOM   7817 C C   . LYS B 1 440 ? -7.54872  14.67038  -31.43184 1.000 48.34501  ? 439 LYS B C   1 
ATOM   7818 O O   . LYS B 1 440 ? -8.30353  13.80594  -31.87420 1.000 50.05937  ? 439 LYS B O   1 
ATOM   7819 C CB  . LYS B 1 440 ? -8.58374  16.92327  -31.00328 1.000 51.79061  ? 439 LYS B CB  1 
ATOM   7820 C CG  . LYS B 1 440 ? -7.91911  17.72678  -29.90117 1.000 53.31135  ? 439 LYS B CG  1 
ATOM   7821 C CD  . LYS B 1 440 ? -8.95148  18.52777  -29.09443 1.000 51.00440  ? 439 LYS B CD  1 
ATOM   7822 C CE  . LYS B 1 440 ? -9.49667  17.71726  -27.91168 1.000 64.08452  ? 439 LYS B CE  1 
ATOM   7823 N NZ  . LYS B 1 440 ? -8.45245  17.26837  -26.90959 1.000 59.60941  ? 439 LYS B NZ  1 
ATOM   7824 N N   . PHE B 1 441 ? -6.60820  14.39189  -30.53811 1.000 48.06373  ? 440 PHE B N   1 
ATOM   7825 C CA  . PHE B 1 441 ? -6.72422  13.12175  -29.82010 1.000 48.72740  ? 440 PHE B CA  1 
ATOM   7826 C C   . PHE B 1 441 ? -6.55523  13.36363  -28.32486 1.000 48.09805  ? 440 PHE B C   1 
ATOM   7827 O O   . PHE B 1 441 ? -7.12204  14.31614  -27.78292 1.000 51.23736  ? 440 PHE B O   1 
ATOM   7828 C CB  . PHE B 1 441 ? -5.70878  12.09192  -30.32394 1.000 46.99973  ? 440 PHE B CB  1 
ATOM   7829 C CG  . PHE B 1 441 ? -5.86419  11.74004  -31.77886 1.000 53.63009  ? 440 PHE B CG  1 
ATOM   7830 C CD1 . PHE B 1 441 ? -5.24481  12.49739  -32.76108 1.000 51.96900  ? 440 PHE B CD1 1 
ATOM   7831 C CD2 . PHE B 1 441 ? -6.61395  10.64089  -32.16867 1.000 54.25951  ? 440 PHE B CD2 1 
ATOM   7832 C CE1 . PHE B 1 441 ? -5.37435  12.17345  -34.09813 1.000 45.09315  ? 440 PHE B CE1 1 
ATOM   7833 C CE2 . PHE B 1 441 ? -6.74584  10.31973  -33.50061 1.000 46.15608  ? 440 PHE B CE2 1 
ATOM   7834 C CZ  . PHE B 1 441 ? -6.12153  11.09043  -34.46428 1.000 47.87312  ? 440 PHE B CZ  1 
ATOM   7835 N N   . SER B 1 442 ? -5.78023  12.51935  -27.65092 1.000 45.71655  ? 441 SER B N   1 
ATOM   7836 C CA  . SER B 1 442 ? -5.49059  12.67640  -26.22549 1.000 47.99951  ? 441 SER B CA  1 
ATOM   7837 C C   . SER B 1 442 ? -4.01240  12.39244  -26.01438 1.000 50.86993  ? 441 SER B C   1 
ATOM   7838 O O   . SER B 1 442 ? -3.62444  11.32199  -25.52591 1.000 50.79515  ? 441 SER B O   1 
ATOM   7839 C CB  . SER B 1 442 ? -6.36343  11.74625  -25.37727 1.000 52.15000  ? 441 SER B CB  1 
ATOM   7840 O OG  . SER B 1 442 ? -7.72248  11.76515  -25.79370 1.000 50.12117  ? 441 SER B OG  1 
ATOM   7841 N N   . PRO B 1 443 ? -3.15210  13.33735  -26.36040 1.000 47.05735  ? 442 PRO B N   1 
ATOM   7842 C CA  . PRO B 1 443 ? -1.70740  13.06343  -26.44944 1.000 44.37552  ? 442 PRO B CA  1 
ATOM   7843 C C   . PRO B 1 443 ? -0.96932  13.23394  -25.12141 1.000 48.04621  ? 442 PRO B C   1 
ATOM   7844 O O   . PRO B 1 443 ? -0.00839  14.00179  -25.01369 1.000 48.64722  ? 442 PRO B O   1 
ATOM   7845 C CB  . PRO B 1 443 ? -1.25450  14.09625  -27.47936 1.000 43.16061  ? 442 PRO B CB  1 
ATOM   7846 C CG  . PRO B 1 443 ? -2.12982  15.27711  -27.15865 1.000 50.48149  ? 442 PRO B CG  1 
ATOM   7847 C CD  . PRO B 1 443 ? -3.45618  14.74449  -26.64114 1.000 44.59091  ? 442 PRO B CD  1 
ATOM   7848 N N   . HIS B 1 444 ? -1.41176  12.50107  -24.09843 1.000 51.21671  ? 443 HIS B N   1 
ATOM   7849 C CA  . HIS B 1 444 ? -0.77732  12.51343  -22.79038 1.000 43.83254  ? 443 HIS B CA  1 
ATOM   7850 C C   . HIS B 1 444 ? 0.08655   11.27041  -22.61217 1.000 49.56243  ? 443 HIS B C   1 
ATOM   7851 O O   . HIS B 1 444 ? 0.14596   10.39566  -23.47874 1.000 53.82523  ? 443 HIS B O   1 
ATOM   7852 C CB  . HIS B 1 444 ? -1.82143  12.59392  -21.69096 1.000 50.09369  ? 443 HIS B CB  1 
ATOM   7853 C CG  . HIS B 1 444 ? -2.89657  11.57127  -21.81787 1.000 51.63638  ? 443 HIS B CG  1 
ATOM   7854 N ND1 . HIS B 1 444 ? -2.66248  10.22503  -21.63913 1.000 52.54825  ? 443 HIS B ND1 1 
ATOM   7855 C CD2 . HIS B 1 444 ? -4.21424  11.69370  -22.10307 1.000 53.45533  ? 443 HIS B CD2 1 
ATOM   7856 C CE1 . HIS B 1 444 ? -3.79313  9.56002   -21.80060 1.000 52.53718  ? 443 HIS B CE1 1 
ATOM   7857 N NE2 . HIS B 1 444 ? -4.74925  10.42794  -22.08664 1.000 58.23690  ? 443 HIS B NE2 1 
ATOM   7858 N N   . GLY B 1 445 ? 0.74038   11.18149  -21.44951 1.000 49.77639  ? 444 GLY B N   1 
ATOM   7859 C CA  . GLY B 1 445 ? 1.83961   10.23914  -21.28224 1.000 42.18537  ? 444 GLY B CA  1 
ATOM   7860 C C   . GLY B 1 445 ? 1.46600   8.79542   -21.54090 1.000 42.67344  ? 444 GLY B C   1 
ATOM   7861 O O   . GLY B 1 445 ? 2.30061   8.00940   -22.00003 1.000 44.54169  ? 444 GLY B O   1 
ATOM   7862 N N   . GLU B 1 446 ? 0.21651   8.42106   -21.25280 1.000 45.34081  ? 445 GLU B N   1 
ATOM   7863 C CA  . GLU B 1 446 ? -0.21682  7.04985   -21.51054 1.000 45.92608  ? 445 GLU B CA  1 
ATOM   7864 C C   . GLU B 1 446 ? -0.19680  6.72472   -22.99980 1.000 49.53629  ? 445 GLU B C   1 
ATOM   7865 O O   . GLU B 1 446 ? 0.20769   5.62727   -23.39642 1.000 54.61004  ? 445 GLU B O   1 
ATOM   7866 C CB  . GLU B 1 446 ? -1.61831  6.82817   -20.95301 1.000 47.01547  ? 445 GLU B CB  1 
ATOM   7867 C CG  . GLU B 1 446 ? -1.68562  5.79875   -19.86198 1.000 56.23543  ? 445 GLU B CG  1 
ATOM   7868 C CD  . GLU B 1 446 ? -3.05049  5.73777   -19.18920 1.000 65.62323  ? 445 GLU B CD  1 
ATOM   7869 O OE1 . GLU B 1 446 ? -4.08517  5.84991   -19.90008 1.000 65.90239  ? 445 GLU B OE1 1 
ATOM   7870 O OE2 . GLU B 1 446 ? -3.07618  5.57299   -17.94471 1.000 68.22280  ? 445 GLU B OE2 1 
ATOM   7871 N N   . ASN B 1 447 ? -0.61137  7.67138   -23.84038 1.000 49.31100  ? 446 ASN B N   1 
ATOM   7872 C CA  . ASN B 1 447 ? -0.94827  7.39683   -25.23052 1.000 47.05656  ? 446 ASN B CA  1 
ATOM   7873 C C   . ASN B 1 447 ? 0.19901   7.59685   -26.21377 1.000 46.50590  ? 446 ASN B C   1 
ATOM   7874 O O   . ASN B 1 447 ? 0.01396   7.29683   -27.39821 1.000 45.39708  ? 446 ASN B O   1 
ATOM   7875 C CB  . ASN B 1 447 ? -2.12755  8.26721   -25.65880 1.000 46.74728  ? 446 ASN B CB  1 
ATOM   7876 C CG  . ASN B 1 447 ? -3.41572  7.84498   -25.00757 1.000 44.58519  ? 446 ASN B CG  1 
ATOM   7877 O OD1 . ASN B 1 447 ? -3.60857  6.67909   -24.69627 1.000 45.96623  ? 446 ASN B OD1 1 
ATOM   7878 N ND2 . ASN B 1 447 ? -4.31013  8.78882   -24.80596 1.000 47.31791  ? 446 ASN B ND2 1 
ATOM   7879 N N   . LEU B 1 448 ? 1.36273   8.08912   -25.77956 1.000 42.79758  ? 447 LEU B N   1 
ATOM   7880 C CA  . LEU B 1 448 ? 2.52522   8.21779   -26.65449 1.000 42.41138  ? 447 LEU B CA  1 
ATOM   7881 C C   . LEU B 1 448 ? 3.60919   7.23172   -26.24002 1.000 40.25520  ? 447 LEU B C   1 
ATOM   7882 O O   . LEU B 1 448 ? 3.98731   7.17946   -25.07043 1.000 46.70402  ? 447 LEU B O   1 
ATOM   7883 C CB  . LEU B 1 448 ? 3.08658   9.63656   -26.63378 1.000 38.41976  ? 447 LEU B CB  1 
ATOM   7884 C CG  . LEU B 1 448 ? 2.40545   10.68936  -27.50966 1.000 38.18693  ? 447 LEU B CG  1 
ATOM   7885 C CD1 . LEU B 1 448 ? 2.21410   10.17823  -28.88945 1.000 38.05192  ? 447 LEU B CD1 1 
ATOM   7886 C CD2 . LEU B 1 448 ? 1.08783   11.10323  -26.93897 1.000 43.74763  ? 447 LEU B CD2 1 
ATOM   7887 N N   . ILE B 1 449 ? 4.09231   6.44665   -27.19463 1.000 39.08768  ? 448 ILE B N   1 
ATOM   7888 C CA  . ILE B 1 449 ? 5.27448   5.61062   -27.02762 1.000 43.16120  ? 448 ILE B CA  1 
ATOM   7889 C C   . ILE B 1 449 ? 6.42023   6.26839   -27.78118 1.000 51.14444  ? 448 ILE B C   1 
ATOM   7890 O O   . ILE B 1 449 ? 6.29952   6.54042   -28.98407 1.000 49.93370  ? 448 ILE B O   1 
ATOM   7891 C CB  . ILE B 1 449 ? 5.04850   4.18882   -27.56054 1.000 42.83462  ? 448 ILE B CB  1 
ATOM   7892 C CG1 . ILE B 1 449 ? 3.69346   3.64628   -27.10230 1.000 44.15271  ? 448 ILE B CG1 1 
ATOM   7893 C CG2 . ILE B 1 449 ? 6.19909   3.30079   -27.15646 1.000 41.68905  ? 448 ILE B CG2 1 
ATOM   7894 C CD1 . ILE B 1 449 ? 3.41450   2.21382   -27.55658 1.000 36.52646  ? 448 ILE B CD1 1 
ATOM   7895 N N   . LEU B 1 450 ? 7.53335   6.50156   -27.08586 1.000 47.73984  ? 449 LEU B N   1 
ATOM   7896 C CA  . LEU B 1 450 ? 8.69201   7.18821   -27.64413 1.000 43.17740  ? 449 LEU B CA  1 
ATOM   7897 C C   . LEU B 1 450 ? 9.71571   6.18275   -28.14769 1.000 46.83692  ? 449 LEU B C   1 
ATOM   7898 O O   . LEU B 1 450 ? 10.10616  5.27725   -27.40224 1.000 45.82390  ? 449 LEU B O   1 
ATOM   7899 C CB  . LEU B 1 450 ? 9.33373   8.07551   -26.58557 1.000 39.63205  ? 449 LEU B CB  1 
ATOM   7900 C CG  . LEU B 1 450 ? 8.36042   9.14677   -26.15177 1.000 44.43618  ? 449 LEU B CG  1 
ATOM   7901 C CD1 . LEU B 1 450 ? 8.94934   9.99743   -25.04507 1.000 45.47745  ? 449 LEU B CD1 1 
ATOM   7902 C CD2 . LEU B 1 450 ? 8.02941   9.97246   -27.37195 1.000 39.69326  ? 449 LEU B CD2 1 
ATOM   7903 N N   . VAL B 1 451 ? 10.16189  6.35251   -29.39783 1.000 45.34633  ? 450 VAL B N   1 
ATOM   7904 C CA  . VAL B 1 451 ? 11.26944  5.56645   -29.94778 1.000 45.31142  ? 450 VAL B CA  1 
ATOM   7905 C C   . VAL B 1 451 ? 12.57175  6.31870   -29.69957 1.000 45.75281  ? 450 VAL B C   1 
ATOM   7906 O O   . VAL B 1 451 ? 12.71650  7.47911   -30.09951 1.000 43.43323  ? 450 VAL B O   1 
ATOM   7907 C CB  . VAL B 1 451 ? 11.09076  5.28085   -31.44559 1.000 40.89862  ? 450 VAL B CB  1 
ATOM   7908 C CG1 . VAL B 1 451 ? 12.12602  4.26643   -31.89846 1.000 40.31880  ? 450 VAL B CG1 1 
ATOM   7909 C CG2 . VAL B 1 451 ? 9.69452   4.78824   -31.73754 1.000 43.37136  ? 450 VAL B CG2 1 
ATOM   7910 N N   . LEU B 1 452 ? 13.52432  5.64946   -29.05474 1.000 46.74398  ? 451 LEU B N   1 
ATOM   7911 C CA  . LEU B 1 452 ? 14.78960  6.24402   -28.65832 1.000 45.11913  ? 451 LEU B CA  1 
ATOM   7912 C C   . LEU B 1 452 ? 15.94523  5.48924   -29.28270 1.000 46.48011  ? 451 LEU B C   1 
ATOM   7913 O O   . LEU B 1 452 ? 15.89363  4.26447   -29.42547 1.000 48.64203  ? 451 LEU B O   1 
ATOM   7914 C CB  . LEU B 1 452 ? 14.96854  6.22593   -27.15244 1.000 44.89742  ? 451 LEU B CB  1 
ATOM   7915 C CG  . LEU B 1 452 ? 14.02687  7.11682   -26.37502 1.000 44.38443  ? 451 LEU B CG  1 
ATOM   7916 C CD1 . LEU B 1 452 ? 14.56775  7.29374   -24.95545 1.000 43.91162  ? 451 LEU B CD1 1 
ATOM   7917 C CD2 . LEU B 1 452 ? 13.88307  8.43788   -27.09764 1.000 41.95714  ? 451 LEU B CD2 1 
ATOM   7918 N N   . ASP B 1 453 ? 16.99163  6.23455   -29.62829 1.000 50.66225  ? 452 ASP B N   1 
ATOM   7919 C CA  . ASP B 1 453 ? 18.26583  5.68681   -30.07577 1.000 52.27356  ? 452 ASP B CA  1 
ATOM   7920 C C   . ASP B 1 453 ? 19.34492  6.17695   -29.12240 1.000 52.93720  ? 452 ASP B C   1 
ATOM   7921 O O   . ASP B 1 453 ? 19.58837  7.38669   -29.02636 1.000 49.00316  ? 452 ASP B O   1 
ATOM   7922 C CB  . ASP B 1 453 ? 18.57978  6.11738   -31.50808 1.000 57.43072  ? 452 ASP B CB  1 
ATOM   7923 C CG  . ASP B 1 453 ? 19.75763  5.37147   -32.08511 1.000 62.69747  ? 452 ASP B CG  1 
ATOM   7924 O OD1 . ASP B 1 453 ? 19.97144  4.21193   -31.66652 1.000 57.57237  ? 452 ASP B OD1 1 
ATOM   7925 O OD2 . ASP B 1 453 ? 20.46614  5.94243   -32.94543 1.000 72.00958  ? 452 ASP B OD2 1 
ATOM   7926 N N   . GLY B 1 454 ? 19.96971  5.24532   -28.40698 1.000 49.78830  ? 453 GLY B N   1 
ATOM   7927 C CA  . GLY B 1 454 ? 20.92537  5.60064   -27.37956 1.000 48.74827  ? 453 GLY B CA  1 
ATOM   7928 C C   . GLY B 1 454 ? 20.47349  6.74608   -26.49403 1.000 56.85846  ? 453 GLY B C   1 
ATOM   7929 O O   . GLY B 1 454 ? 21.30670  7.52986   -26.02779 1.000 58.76054  ? 453 GLY B O   1 
ATOM   7930 N N   . GLY B 1 455 ? 19.16028  6.86656   -26.26474 1.000 51.06723  ? 454 GLY B N   1 
ATOM   7931 C CA  . GLY B 1 455 ? 18.62556  7.90607   -25.41652 1.000 45.30434  ? 454 GLY B CA  1 
ATOM   7932 C C   . GLY B 1 455 ? 18.22594  9.17681   -26.12286 1.000 48.92471  ? 454 GLY B C   1 
ATOM   7933 O O   . GLY B 1 455 ? 17.84139  10.14608  -25.45341 1.000 48.41680  ? 454 GLY B O   1 
ATOM   7934 N N   . ALA B 1 456 ? 18.30552  9.21671   -27.44048 1.000 52.12287  ? 455 ALA B N   1 
ATOM   7935 C CA  . ALA B 1 456 ? 17.88979  10.44822  -28.08902 1.000 51.87106  ? 455 ALA B CA  1 
ATOM   7936 C C   . ALA B 1 456 ? 16.56527  10.23514  -28.79959 1.000 46.39404  ? 455 ALA B C   1 
ATOM   7937 O O   . ALA B 1 456 ? 16.34691  9.16688   -29.37921 1.000 45.52440  ? 455 ALA B O   1 
ATOM   7938 C CB  . ALA B 1 456 ? 18.93625  10.93355  -29.10163 1.000 50.85558  ? 455 ALA B CB  1 
ATOM   7939 N N   . PRO B 1 457 ? 15.66312  11.20918  -28.74764 1.000 42.04672  ? 456 PRO B N   1 
ATOM   7940 C CA  . PRO B 1 457 ? 14.40225  11.09235  -29.48590 1.000 44.51871  ? 456 PRO B CA  1 
ATOM   7941 C C   . PRO B 1 457 ? 14.66725  10.76883  -30.94649 1.000 50.09651  ? 456 PRO B C   1 
ATOM   7942 O O   . PRO B 1 457 ? 15.62784  11.27192  -31.53352 1.000 56.42710  ? 456 PRO B O   1 
ATOM   7943 C CB  . PRO B 1 457 ? 13.77317  12.47982  -29.33494 1.000 43.89890  ? 456 PRO B CB  1 
ATOM   7944 C CG  . PRO B 1 457 ? 14.40251  13.05277  -28.13053 1.000 49.68884  ? 456 PRO B CG  1 
ATOM   7945 C CD  . PRO B 1 457 ? 15.78690  12.49107  -28.04780 1.000 46.54593  ? 456 PRO B CD  1 
ATOM   7946 N N   . VAL B 1 458 ? 13.82856  9.90003   -31.53113 1.000 44.84766  ? 457 VAL B N   1 
ATOM   7947 C CA  . VAL B 1 458 ? 13.84617  9.72474   -32.98160 1.000 43.54930  ? 457 VAL B CA  1 
ATOM   7948 C C   . VAL B 1 458 ? 12.43470  9.91877   -33.54308 1.000 48.66023  ? 457 VAL B C   1 
ATOM   7949 O O   . VAL B 1 458 ? 12.26861  10.54177  -34.60154 1.000 53.28839  ? 457 VAL B O   1 
ATOM   7950 C CB  . VAL B 1 458 ? 14.45468  8.36750   -33.42107 1.000 41.61577  ? 457 VAL B CB  1 
ATOM   7951 C CG1 . VAL B 1 458 ? 15.71029  8.02142   -32.63617 1.000 38.27953  ? 457 VAL B CG1 1 
ATOM   7952 C CG2 . VAL B 1 458 ? 13.45012  7.23472   -33.40275 1.000 53.27354  ? 457 VAL B CG2 1 
ATOM   7953 N N   . ARG B 1 459 ? 11.40559  9.43598   -32.83903 1.000 46.91205  ? 458 ARG B N   1 
ATOM   7954 C CA  . ARG B 1 459 ? 10.04146  9.48411   -33.36741 1.000 45.30629  ? 458 ARG B CA  1 
ATOM   7955 C C   . ARG B 1 459 ? 9.08171   8.96924   -32.30958 1.000 46.88998  ? 458 ARG B C   1 
ATOM   7956 O O   . ARG B 1 459 ? 9.49296   8.39343   -31.29889 1.000 54.91907  ? 458 ARG B O   1 
ATOM   7957 C CB  . ARG B 1 459 ? 9.89050   8.65338   -34.62986 1.000 47.79790  ? 458 ARG B CB  1 
ATOM   7958 C CG  . ARG B 1 459 ? 9.88174   7.19469   -34.34944 1.000 46.26814  ? 458 ARG B CG  1 
ATOM   7959 C CD  . ARG B 1 459 ? 10.34113  6.43686   -35.55228 1.000 42.83617  ? 458 ARG B CD  1 
ATOM   7960 N NE  . ARG B 1 459 ? 9.39381   5.38238   -35.87513 1.000 44.13418  ? 458 ARG B NE  1 
ATOM   7961 C CZ  . ARG B 1 459 ? 9.70598   4.09737   -35.96080 1.000 55.84322  ? 458 ARG B CZ  1 
ATOM   7962 N NH1 . ARG B 1 459 ? 10.94617  3.66550   -35.73758 1.000 52.32769  ? 458 ARG B NH1 1 
ATOM   7963 N NH2 . ARG B 1 459 ? 8.75559   3.22522   -36.29515 1.000 55.51582  ? 458 ARG B NH2 1 
ATOM   7964 N N   . ALA B 1 460 ? 7.79026   9.15125   -32.56926 1.000 45.84220  ? 459 ALA B N   1 
ATOM   7965 C CA  . ALA B 1 460 ? 6.76187   8.82543   -31.59526 1.000 42.00650  ? 459 ALA B CA  1 
ATOM   7966 C C   . ALA B 1 460 ? 5.62260   8.05352   -32.24392 1.000 45.69608  ? 459 ALA B C   1 
ATOM   7967 O O   . ALA B 1 460 ? 5.32284   8.22834   -33.42935 1.000 43.09160  ? 459 ALA B O   1 
ATOM   7968 C CB  . ALA B 1 460 ? 6.21027   10.08742  -30.93327 1.000 35.94639  ? 459 ALA B CB  1 
ATOM   7969 N N   . VAL B 1 461 ? 4.97741   7.21013   -31.43559 1.000 47.61402  ? 460 VAL B N   1 
ATOM   7970 C CA  . VAL B 1 461 ? 3.79026   6.45826   -31.82531 1.000 41.36038  ? 460 VAL B CA  1 
ATOM   7971 C C   . VAL B 1 461 ? 2.62126   6.95738   -30.99783 1.000 41.81963  ? 460 VAL B C   1 
ATOM   7972 O O   . VAL B 1 461 ? 2.76281   7.15887   -29.78739 1.000 45.00395  ? 460 VAL B O   1 
ATOM   7973 C CB  . VAL B 1 461 ? 3.97900   4.94870   -31.60200 1.000 41.44624  ? 460 VAL B CB  1 
ATOM   7974 C CG1 . VAL B 1 461 ? 2.71746   4.20081   -31.97861 1.000 36.95873  ? 460 VAL B CG1 1 
ATOM   7975 C CG2 . VAL B 1 461 ? 5.18493   4.44244   -32.36174 1.000 34.50370  ? 460 VAL B CG2 1 
ATOM   7976 N N   . LEU B 1 462 ? 1.46887   7.14538   -31.64194 1.000 41.22528  ? 461 LEU B N   1 
ATOM   7977 C CA  . LEU B 1 462 ? 0.22971   7.53170   -30.97895 1.000 38.10206  ? 461 LEU B CA  1 
ATOM   7978 C C   . LEU B 1 462 ? -0.69684  6.33172   -30.91071 1.000 42.90790  ? 461 LEU B C   1 
ATOM   7979 O O   . LEU B 1 462 ? -0.60147  5.42055   -31.73130 1.000 42.37651  ? 461 LEU B O   1 
ATOM   7980 C CB  . LEU B 1 462 ? -0.44973  8.68402   -31.71023 1.000 35.82803  ? 461 LEU B CB  1 
ATOM   7981 C CG  . LEU B 1 462 ? -1.74046  9.27608   -31.15050 1.000 38.24577  ? 461 LEU B CG  1 
ATOM   7982 C CD1 . LEU B 1 462 ? -1.49507  10.31451  -30.09394 1.000 36.88916  ? 461 LEU B CD1 1 
ATOM   7983 C CD2 . LEU B 1 462 ? -2.56112  9.88042   -32.29725 1.000 50.84115  ? 461 LEU B CD2 1 
ATOM   7984 N N   . LYS B 1 463 ? -1.60529  6.34253   -29.92430 1.000 50.62753  ? 462 LYS B N   1 
ATOM   7985 C CA  . LYS B 1 463 ? -2.29624  5.11479   -29.53377 1.000 49.97274  ? 462 LYS B CA  1 
ATOM   7986 C C   . LYS B 1 463 ? -3.81889  5.20192   -29.41811 1.000 55.33993  ? 462 LYS B C   1 
ATOM   7987 O O   . LYS B 1 463 ? -4.53334  4.64669   -30.26072 1.000 63.15251  ? 462 LYS B O   1 
ATOM   7988 C CB  . LYS B 1 463 ? -1.74031  4.62140   -28.20765 1.000 47.96752  ? 462 LYS B CB  1 
ATOM   7989 C CG  . LYS B 1 463 ? -1.78942  3.12211   -28.06412 1.000 48.62171  ? 462 LYS B CG  1 
ATOM   7990 C CD  . LYS B 1 463 ? -0.82930  2.66006   -26.98367 1.000 57.95157  ? 462 LYS B CD  1 
ATOM   7991 C CE  . LYS B 1 463 ? -0.98866  3.49341   -25.70379 1.000 54.82413  ? 462 LYS B CE  1 
ATOM   7992 N NZ  . LYS B 1 463 ? -2.42325  3.63077   -25.30574 1.000 50.63709  ? 462 LYS B NZ  1 
ATOM   7993 N N   . ASP B 1 464 ? -4.33901  5.81510   -28.35733 1.000 50.43664  ? 463 ASP B N   1 
ATOM   7994 C CA  . ASP B 1 464 ? -5.78580  5.78406   -28.11328 1.000 54.53984  ? 463 ASP B CA  1 
ATOM   7995 C C   . ASP B 1 464 ? -6.46408  6.69540   -29.13393 1.000 53.89012  ? 463 ASP B C   1 
ATOM   7996 O O   . ASP B 1 464 ? -6.32466  7.92071   -29.04443 1.000 57.44697  ? 463 ASP B O   1 
ATOM   7997 C CB  . ASP B 1 464 ? -6.08054  6.22053   -26.67080 1.000 53.99351  ? 463 ASP B CB  1 
ATOM   7998 C CG  . ASP B 1 464 ? -7.43268  5.72540   -26.14526 1.000 55.01450  ? 463 ASP B CG  1 
ATOM   7999 O OD1 . ASP B 1 464 ? -8.17038  5.05756   -26.89459 1.000 62.15837  ? 463 ASP B OD1 1 
ATOM   8000 O OD2 . ASP B 1 464 ? -7.78215  6.03592   -24.98444 1.000 55.62714  ? 463 ASP B OD2 1 
ATOM   8001 N N   . ILE B 1 465 ? -7.17568  6.11854   -30.12028 1.000 49.30437  ? 464 ILE B N   1 
ATOM   8002 C CA  . ILE B 1 465 ? -7.62183  6.91368   -31.27299 1.000 52.12847  ? 464 ILE B CA  1 
ATOM   8003 C C   . ILE B 1 465 ? -9.12002  6.83472   -31.53461 1.000 49.24372  ? 464 ILE B C   1 
ATOM   8004 O O   . ILE B 1 465 ? -9.78479  7.87034   -31.64422 1.000 49.29244  ? 464 ILE B O   1 
ATOM   8005 C CB  . ILE B 1 465 ? -6.85261  6.53208   -32.55181 1.000 50.74481  ? 464 ILE B CB  1 
ATOM   8006 C CG1 . ILE B 1 465 ? -6.54146  5.06051   -32.56454 1.000 51.01445  ? 464 ILE B CG1 1 
ATOM   8007 C CG2 . ILE B 1 465 ? -5.52511  7.25714   -32.64808 1.000 54.31885  ? 464 ILE B CG2 1 
ATOM   8008 C CD1 . ILE B 1 465 ? -5.87724  4.66734   -33.83653 1.000 58.36426  ? 464 ILE B CD1 1 
ATOM   8009 N N   . GLY B 1 466 ? -9.65859  5.62933   -31.68389 1.000 43.88209  ? 465 GLY B N   1 
ATOM   8010 C CA  . GLY B 1 466 ? -11.08703 5.49588   -31.91597 1.000 42.57136  ? 465 GLY B CA  1 
ATOM   8011 C C   . GLY B 1 466 ? -11.95218 6.21322   -30.89340 1.000 49.97606  ? 465 GLY B C   1 
ATOM   8012 O O   . GLY B 1 466 ? -12.68749 7.14226   -31.22718 1.000 50.98905  ? 465 GLY B O   1 
ATOM   8013 N N   . GLU B 1 467 ? -11.84938 5.80226   -29.63136 1.000 53.08817  ? 466 GLU B N   1 
ATOM   8014 C CA  . GLU B 1 467 ? -12.66838 6.33607   -28.55132 1.000 50.89156  ? 466 GLU B CA  1 
ATOM   8015 C C   . GLU B 1 467 ? -12.32487 7.78044   -28.20180 1.000 53.62552  ? 466 GLU B C   1 
ATOM   8016 O O   . GLU B 1 467 ? -13.12693 8.45152   -27.54376 1.000 65.23459  ? 466 GLU B O   1 
ATOM   8017 C CB  . GLU B 1 467 ? -12.52616 5.39469   -27.33757 1.000 61.58977  ? 466 GLU B CB  1 
ATOM   8018 C CG  . GLU B 1 467 ? -12.56602 5.99833   -25.93814 1.000 58.27998  ? 466 GLU B CG  1 
ATOM   8019 C CD  . GLU B 1 467 ? -11.97241 5.06958   -24.87436 1.000 65.04242  ? 466 GLU B CD  1 
ATOM   8020 O OE1 . GLU B 1 467 ? -12.74449 4.23300   -24.35580 1.000 58.67716  ? 466 GLU B OE1 1 
ATOM   8021 O OE2 . GLU B 1 467 ? -10.75344 5.19044   -24.54347 1.000 63.79442  ? 466 GLU B OE2 1 
ATOM   8022 N N   . GLU B 1 468 ? -11.19977 8.30539   -28.67709 1.000 52.10956  ? 467 GLU B N   1 
ATOM   8023 C CA  . GLU B 1 468 ? -10.73504 9.61276   -28.24156 1.000 53.80802  ? 467 GLU B CA  1 
ATOM   8024 C C   . GLU B 1 468 ? -10.79249 10.71486  -29.29758 1.000 58.27335  ? 467 GLU B C   1 
ATOM   8025 O O   . GLU B 1 468 ? -10.59384 11.88745  -28.94213 1.000 57.91973  ? 467 GLU B O   1 
ATOM   8026 C CB  . GLU B 1 468 ? -9.29568  9.49849   -27.73348 1.000 49.61608  ? 467 GLU B CB  1 
ATOM   8027 C CG  . GLU B 1 468 ? -9.14829  8.52822   -26.62189 1.000 54.03369  ? 467 GLU B CG  1 
ATOM   8028 C CD  . GLU B 1 468 ? -9.51518  9.13660   -25.30379 1.000 61.94337  ? 467 GLU B CD  1 
ATOM   8029 O OE1 . GLU B 1 468 ? -9.45163  10.38302  -25.20793 1.000 61.72709  ? 467 GLU B OE1 1 
ATOM   8030 O OE2 . GLU B 1 468 ? -9.86699  8.37513   -24.37146 1.000 69.96952  ? 467 GLU B OE2 1 
ATOM   8031 N N   . ILE B 1 469 ? -11.04544 10.39500  -30.57011 1.000 56.06256  ? 468 ILE B N   1 
ATOM   8032 C CA  . ILE B 1 469 ? -10.79280 11.35992  -31.64129 1.000 54.97803  ? 468 ILE B CA  1 
ATOM   8033 C C   . ILE B 1 469 ? -11.94129 12.35245  -31.75312 1.000 56.19780  ? 468 ILE B C   1 
ATOM   8034 O O   . ILE B 1 469 ? -13.11520 11.97137  -31.71870 1.000 62.39543  ? 468 ILE B O   1 
ATOM   8035 C CB  . ILE B 1 469 ? -10.54591 10.65961  -32.98740 1.000 54.13150  ? 468 ILE B CB  1 
ATOM   8036 C CG1 . ILE B 1 469 ? -10.20724 11.72637  -34.02908 1.000 53.84583  ? 468 ILE B CG1 1 
ATOM   8037 C CG2 . ILE B 1 469 ? -11.76186 9.83792   -33.43282 1.000 48.46266  ? 468 ILE B CG2 1 
ATOM   8038 C CD1 . ILE B 1 469 ? -9.42925  11.25186  -35.21229 1.000 49.09635  ? 468 ILE B CD1 1 
ATOM   8039 N N   . CYS B 1 470 ? -11.59527 13.63683  -31.87321 1.000 59.27672  ? 469 CYS B N   1 
ATOM   8040 C CA  . CYS B 1 470 ? -12.51992 14.69003  -32.27542 1.000 56.12397  ? 469 CYS B CA  1 
ATOM   8041 C C   . CYS B 1 470 ? -12.25984 14.99398  -33.74074 1.000 53.50728  ? 469 CYS B C   1 
ATOM   8042 O O   . CYS B 1 470 ? -11.13128 15.35517  -34.10358 1.000 49.42544  ? 469 CYS B O   1 
ATOM   8043 C CB  . CYS B 1 470 ? -12.33278 15.95933  -31.44266 1.000 55.48907  ? 469 CYS B CB  1 
ATOM   8044 S SG  . CYS B 1 470 ? -12.67298 15.78289  -29.67988 1.000 79.20934  ? 469 CYS B SG  1 
ATOM   8045 N N   . ILE B 1 471 ? -13.28666 14.82155  -34.57978 1.000 55.64055  ? 470 ILE B N   1 
ATOM   8046 C CA  . ILE B 1 471 ? -13.24797 15.26875  -35.96940 1.000 54.79666  ? 470 ILE B CA  1 
ATOM   8047 C C   . ILE B 1 471 ? -13.91373 16.63591  -36.04631 1.000 59.61129  ? 470 ILE B C   1 
ATOM   8048 O O   . ILE B 1 471 ? -15.09243 16.78345  -35.70383 1.000 61.15353  ? 470 ILE B O   1 
ATOM   8049 C CB  . ILE B 1 471 ? -13.92470 14.27576  -36.92290 1.000 52.13810  ? 470 ILE B CB  1 
ATOM   8050 C CG1 . ILE B 1 471 ? -13.37221 12.86969  -36.75096 1.000 54.09934  ? 470 ILE B CG1 1 
ATOM   8051 C CG2 . ILE B 1 471 ? -13.71418 14.69968  -38.35898 1.000 58.42892  ? 470 ILE B CG2 1 
ATOM   8052 C CD1 . ILE B 1 471 ? -14.35021 11.80369  -37.22745 1.000 60.74126  ? 470 ILE B CD1 1 
ATOM   8053 N N   . PHE B 1 472 ? -13.15306 17.64002  -36.48097 1.000 57.22629  ? 471 PHE B N   1 
ATOM   8054 C CA  . PHE B 1 472 ? -13.67432 18.99142  -36.60568 1.000 56.72235  ? 471 PHE B CA  1 
ATOM   8055 C C   . PHE B 1 472 ? -14.17879 19.29230  -38.00994 1.000 60.79241  ? 471 PHE B C   1 
ATOM   8056 O O   . PHE B 1 472 ? -15.19646 19.97553  -38.16348 1.000 66.73136  ? 471 PHE B O   1 
ATOM   8057 C CB  . PHE B 1 472 ? -12.59859 20.00317  -36.22132 1.000 59.01685  ? 471 PHE B CB  1 
ATOM   8058 C CG  . PHE B 1 472 ? -12.31044 20.05327  -34.74897 1.000 57.21277  ? 471 PHE B CG  1 
ATOM   8059 C CD1 . PHE B 1 472 ? -13.30541 20.37651  -33.84766 1.000 58.83557  ? 471 PHE B CD1 1 
ATOM   8060 C CD2 . PHE B 1 472 ? -11.03968 19.78784  -34.27052 1.000 54.95553  ? 471 PHE B CD2 1 
ATOM   8061 C CE1 . PHE B 1 472 ? -13.03978 20.42583  -32.49393 1.000 65.23565  ? 471 PHE B CE1 1 
ATOM   8062 C CE2 . PHE B 1 472 ? -10.76497 19.83210  -32.92305 1.000 56.89800  ? 471 PHE B CE2 1 
ATOM   8063 C CZ  . PHE B 1 472 ? -11.76513 20.14872  -32.02863 1.000 61.27862  ? 471 PHE B CZ  1 
ATOM   8064 N N   . ASP B 1 473 ? -13.50140 18.77496  -39.03071 1.000 64.70234  ? 472 ASP B N   1 
ATOM   8065 C CA  . ASP B 1 473 ? -13.72401 19.13313  -40.43697 1.000 69.44256  ? 472 ASP B CA  1 
ATOM   8066 C C   . ASP B 1 473 ? -14.48644 18.03660  -41.17546 1.000 76.21386  ? 472 ASP B C   1 
ATOM   8067 O O   . ASP B 1 473 ? -14.05498 17.54941  -42.22768 1.000 72.05603  ? 472 ASP B O   1 
ATOM   8068 C CB  . ASP B 1 473 ? -12.37964 19.42232  -41.10338 1.000 68.50898  ? 472 ASP B CB  1 
ATOM   8069 C CG  . ASP B 1 473 ? -12.50413 19.95153  -42.53446 1.000 76.19186  ? 472 ASP B CG  1 
ATOM   8070 O OD1 . ASP B 1 473 ? -13.63052 20.28522  -42.97861 1.000 73.07821  ? 472 ASP B OD1 1 
ATOM   8071 O OD2 . ASP B 1 473 ? -11.44165 20.04255  -43.20481 1.000 73.23735  ? 472 ASP B OD2 1 
ATOM   8072 N N   . ALA B 1 474 ? -15.64559 17.64582  -40.61500 1.000 75.84796  ? 473 ALA B N   1 
ATOM   8073 C CA  . ALA B 1 474 ? -16.48322 16.54447  -41.08702 1.000 77.51178  ? 473 ALA B CA  1 
ATOM   8074 C C   . ALA B 1 474 ? -16.83324 16.67824  -42.56888 1.000 86.13164  ? 473 ALA B C   1 
ATOM   8075 O O   . ALA B 1 474 ? -17.76597 17.41704  -42.91803 1.000 90.63319  ? 473 ALA B O   1 
ATOM   8076 C CB  . ALA B 1 474 ? -17.76110 16.47873  -40.25154 1.000 70.90886  ? 473 ALA B CB  1 
ATOM   8077 N N   . PRO B 1 475 ? -16.12732 15.95819  -43.47648 1.000 81.60932  ? 474 PRO B N   1 
ATOM   8078 C CA  . PRO B 1 475 ? -16.36759 16.13554  -44.91974 1.000 78.12849  ? 474 PRO B CA  1 
ATOM   8079 C C   . PRO B 1 475 ? -17.66639 15.51258  -45.42053 1.000 80.45164  ? 474 PRO B C   1 
ATOM   8080 O O   . PRO B 1 475 ? -18.49116 15.01737  -44.64139 1.000 76.77559  ? 474 PRO B O   1 
ATOM   8081 C CB  . PRO B 1 475 ? -15.15034 15.45402  -45.57083 1.000 74.69945  ? 474 PRO B CB  1 
ATOM   8082 C CG  . PRO B 1 475 ? -14.21507 15.11207  -44.43712 1.000 75.43964  ? 474 PRO B CG  1 
ATOM   8083 C CD  . PRO B 1 475 ? -15.07457 14.96298  -43.22695 1.000 76.64582  ? 474 PRO B CD  1 
ATOM   8084 N N   . ASP B 1 476 ? -17.83100 15.51536  -46.74885 1.000 82.11266  ? 475 ASP B N   1 
ATOM   8085 C CA  . ASP B 1 476 ? -19.12577 15.20427  -47.34954 1.000 74.88668  ? 475 ASP B CA  1 
ATOM   8086 C C   . ASP B 1 476 ? -19.50117 13.74320  -47.15536 1.000 73.09991  ? 475 ASP B C   1 
ATOM   8087 O O   . ASP B 1 476 ? -20.66521 13.42743  -46.88274 1.000 75.63583  ? 475 ASP B O   1 
ATOM   8088 C CB  . ASP B 1 476 ? -19.11297 15.54451  -48.83779 1.000 70.43431  ? 475 ASP B CB  1 
ATOM   8089 C CG  . ASP B 1 476 ? -18.95807 17.03073  -49.10356 1.000 77.23992  ? 475 ASP B CG  1 
ATOM   8090 O OD1 . ASP B 1 476 ? -17.80807 17.52314  -49.06699 1.000 83.45191  ? 475 ASP B OD1 1 
ATOM   8091 O OD2 . ASP B 1 476 ? -19.97936 17.70233  -49.37124 1.000 78.15796  ? 475 ASP B OD2 1 
ATOM   8092 N N   . ASP B 1 477 ? -18.53887 12.83671  -47.29820 1.000 71.95256  ? 476 ASP B N   1 
ATOM   8093 C CA  . ASP B 1 477 ? -18.81591 11.40762  -47.23202 1.000 79.35915  ? 476 ASP B CA  1 
ATOM   8094 C C   . ASP B 1 477 ? -18.16224 10.73267  -46.02015 1.000 80.59107  ? 476 ASP B C   1 
ATOM   8095 O O   . ASP B 1 477 ? -17.81162 9.54903   -46.07479 1.000 76.16588  ? 476 ASP B O   1 
ATOM   8096 C CB  . ASP B 1 477 ? -18.41299 10.73211  -48.54858 1.000 77.45360  ? 476 ASP B CB  1 
ATOM   8097 C CG  . ASP B 1 477 ? -16.95024 10.96468  -48.92561 1.000 83.16632  ? 476 ASP B CG  1 
ATOM   8098 O OD1 . ASP B 1 477 ? -16.21927 9.95783   -49.10942 1.000 85.15393  ? 476 ASP B OD1 1 
ATOM   8099 O OD2 . ASP B 1 477 ? -16.53663 12.14772  -49.04040 1.000 82.47101  ? 476 ASP B OD2 1 
ATOM   8100 N N   . ILE B 1 478 ? -18.01470 11.46661  -44.91708 1.000 76.29033  ? 477 ILE B N   1 
ATOM   8101 C CA  . ILE B 1 478 ? -17.66692 10.87750  -43.62493 1.000 75.25647  ? 477 ILE B CA  1 
ATOM   8102 C C   . ILE B 1 478 ? -18.69163 9.78783   -43.31917 1.000 79.69322  ? 477 ILE B C   1 
ATOM   8103 O O   . ILE B 1 478 ? -19.90455 10.05986  -43.33013 1.000 79.45373  ? 477 ILE B O   1 
ATOM   8104 C CB  . ILE B 1 478 ? -17.61640 11.94872  -42.51791 1.000 75.57978  ? 477 ILE B CB  1 
ATOM   8105 C CG1 . ILE B 1 478 ? -17.30746 11.32178  -41.15900 1.000 66.15049  ? 477 ILE B CG1 1 
ATOM   8106 C CG2 . ILE B 1 478 ? -18.90375 12.77709  -42.46588 1.000 71.61295  ? 477 ILE B CG2 1 
ATOM   8107 C CD1 . ILE B 1 478 ? -15.84750 11.15247  -40.88862 1.000 64.86463  ? 477 ILE B CD1 1 
ATOM   8108 N N   . PRO B 1 479 ? -18.27208 8.54167   -43.09123 1.000 70.95294  ? 478 PRO B N   1 
ATOM   8109 C CA  . PRO B 1 479 ? -19.25493 7.48309   -42.84637 1.000 67.76069  ? 478 PRO B CA  1 
ATOM   8110 C C   . PRO B 1 479 ? -20.07959 7.79585   -41.61079 1.000 67.89374  ? 478 PRO B C   1 
ATOM   8111 O O   . PRO B 1 479 ? -19.60918 8.45054   -40.68121 1.000 66.42655  ? 478 PRO B O   1 
ATOM   8112 C CB  . PRO B 1 479 ? -18.39097 6.23358   -42.65932 1.000 65.26068  ? 478 PRO B CB  1 
ATOM   8113 C CG  . PRO B 1 479 ? -17.12733 6.55050   -43.41654 1.000 59.23150  ? 478 PRO B CG  1 
ATOM   8114 C CD  . PRO B 1 479 ? -16.90094 8.01109   -43.16963 1.000 63.34476  ? 478 PRO B CD  1 
ATOM   8115 N N   . GLU B 1 480 ? -21.34363 7.35582   -41.62730 1.000 73.57917  ? 479 GLU B N   1 
ATOM   8116 C CA  . GLU B 1 480 ? -22.20546 7.55188   -40.46434 1.000 66.01927  ? 479 GLU B CA  1 
ATOM   8117 C C   . GLU B 1 480 ? -21.63262 6.88393   -39.22568 1.000 70.21524  ? 479 GLU B C   1 
ATOM   8118 O O   . GLU B 1 480 ? -22.05634 7.18868   -38.10444 1.000 76.38861  ? 479 GLU B O   1 
ATOM   8119 C CB  . GLU B 1 480 ? -23.60841 7.01165   -40.73286 1.000 59.96729  ? 479 GLU B CB  1 
ATOM   8120 N N   . SER B 1 481 ? -20.64894 6.00924   -39.40473 1.000 72.67237  ? 480 SER B N   1 
ATOM   8121 C CA  . SER B 1 481 ? -19.94219 5.35615   -38.31334 1.000 72.73589  ? 480 SER B CA  1 
ATOM   8122 C C   . SER B 1 481 ? -19.13007 6.34962   -37.47699 1.000 68.39745  ? 480 SER B C   1 
ATOM   8123 O O   . SER B 1 481 ? -18.29574 5.94781   -36.66744 1.000 67.27972  ? 480 SER B O   1 
ATOM   8124 C CB  . SER B 1 481 ? -19.04257 4.26000   -38.90950 1.000 66.79565  ? 480 SER B CB  1 
ATOM   8125 O OG  . SER B 1 481 ? -19.42631 3.92365   -40.24372 1.000 65.32804  ? 480 SER B OG  1 
ATOM   8126 N N   . CYS B 1 482 ? -19.35223 7.65034   -37.66260 1.000 66.56622  ? 481 CYS B N   1 
ATOM   8127 C CA  . CYS B 1 482 ? -18.52402 8.67485   -37.03584 1.000 69.29714  ? 481 CYS B CA  1 
ATOM   8128 C C   . CYS B 1 482 ? -19.34433 9.77684   -36.37087 1.000 75.79789  ? 481 CYS B C   1 
ATOM   8129 O O   . CYS B 1 482 ? -18.77439 10.80701  -35.98736 1.000 73.22880  ? 481 CYS B O   1 
ATOM   8130 C CB  . CYS B 1 482 ? -17.55613 9.31103   -38.05437 1.000 65.05145  ? 481 CYS B CB  1 
ATOM   8131 S SG  . CYS B 1 482 ? -16.40048 8.19024   -38.96518 1.000 70.65129  ? 481 CYS B SG  1 
ATOM   8132 N N   . ARG B 1 483 ? -20.65905 9.59554   -36.21558 1.000 75.73613  ? 482 ARG B N   1 
ATOM   8133 C CA  . ARG B 1 483 ? -21.46601 10.63430  -35.58410 1.000 73.02493  ? 482 ARG B CA  1 
ATOM   8134 C C   . ARG B 1 483 ? -20.88851 11.03005  -34.22970 1.000 75.62054  ? 482 ARG B C   1 
ATOM   8135 O O   . ARG B 1 483 ? -20.90558 12.21046  -33.86318 1.000 80.27484  ? 482 ARG B O   1 
ATOM   8136 C CB  . ARG B 1 483 ? -22.91830 10.15853  -35.43787 1.000 70.51172  ? 482 ARG B CB  1 
ATOM   8137 N N   . ARG B 1 484 ? -20.33305 10.05915  -33.48967 1.000 73.24007  ? 483 ARG B N   1 
ATOM   8138 C CA  . ARG B 1 484 ? -19.85019 10.33032  -32.13670 1.000 70.20674  ? 483 ARG B CA  1 
ATOM   8139 C C   . ARG B 1 484 ? -18.58104 11.17722  -32.13377 1.000 67.51521  ? 483 ARG B C   1 
ATOM   8140 O O   . ARG B 1 484 ? -18.33954 11.92387  -31.17932 1.000 66.22021  ? 483 ARG B O   1 
ATOM   8141 C CB  . ARG B 1 484 ? -19.60988 9.01572   -31.37924 1.000 75.57717  ? 483 ARG B CB  1 
ATOM   8142 C CG  . ARG B 1 484 ? -19.27930 7.79109   -32.26086 1.000 72.30389  ? 483 ARG B CG  1 
ATOM   8143 C CD  . ARG B 1 484 ? -18.98828 6.52546   -31.41630 1.000 66.59006  ? 483 ARG B CD  1 
ATOM   8144 N NE  . ARG B 1 484 ? -17.76020 6.63666   -30.62764 1.000 71.51659  ? 483 ARG B NE  1 
ATOM   8145 C CZ  . ARG B 1 484 ? -16.68265 5.86818   -30.77074 1.000 68.66628  ? 483 ARG B CZ  1 
ATOM   8146 N NH1 . ARG B 1 484 ? -16.64066 4.88427   -31.66009 1.000 60.82978  ? 483 ARG B NH1 1 
ATOM   8147 N NH2 . ARG B 1 484 ? -15.62117 6.08549   -29.99359 1.000 67.07054  ? 483 ARG B NH2 1 
ATOM   8148 N N   . ALA B 1 485 ? -17.76285 11.08710  -33.17906 1.000 65.16604  ? 484 ALA B N   1 
ATOM   8149 C CA  . ALA B 1 485 ? -16.49520 11.80783  -33.18293 1.000 61.75041  ? 484 ALA B CA  1 
ATOM   8150 C C   . ALA B 1 485 ? -16.60109 13.22160  -33.73892 1.000 64.07494  ? 484 ALA B C   1 
ATOM   8151 O O   . ALA B 1 485 ? -15.79589 14.08382  -33.37089 1.000 62.20532  ? 484 ALA B O   1 
ATOM   8152 C CB  . ALA B 1 485 ? -15.45246 11.03125  -33.98454 1.000 56.78266  ? 484 ALA B CB  1 
ATOM   8153 N N   . VAL B 1 486 ? -17.56559 13.48190  -34.61640 1.000 65.87191  ? 485 VAL B N   1 
ATOM   8154 C CA  . VAL B 1 486 ? -17.70344 14.79184  -35.24578 1.000 65.64989  ? 485 VAL B CA  1 
ATOM   8155 C C   . VAL B 1 486 ? -18.37622 15.74146  -34.25974 1.000 69.06779  ? 485 VAL B C   1 
ATOM   8156 O O   . VAL B 1 486 ? -19.52890 15.54026  -33.87045 1.000 73.24761  ? 485 VAL B O   1 
ATOM   8157 C CB  . VAL B 1 486 ? -18.47358 14.70358  -36.56850 1.000 66.79137  ? 485 VAL B CB  1 
ATOM   8158 C CG1 . VAL B 1 486 ? -17.59649 14.06129  -37.63461 1.000 65.13743  ? 485 VAL B CG1 1 
ATOM   8159 C CG2 . VAL B 1 486 ? -19.74719 13.87190  -36.38954 1.000 70.03099  ? 485 VAL B CG2 1 
ATOM   8160 N N   . THR B 1 487 ? -17.63559 16.76224  -33.82624 1.000 68.24352  ? 486 THR B N   1 
ATOM   8161 C CA  . THR B 1 487 ? -18.11643 17.73878  -32.85302 1.000 73.54913  ? 486 THR B CA  1 
ATOM   8162 C C   . THR B 1 487 ? -17.68463 19.12217  -33.31610 1.000 73.70427  ? 486 THR B C   1 
ATOM   8163 O O   . THR B 1 487 ? -16.48722 19.37571  -33.46872 1.000 77.38420  ? 486 THR B O   1 
ATOM   8164 C CB  . THR B 1 487 ? -17.57479 17.46513  -31.43052 1.000 75.86799  ? 486 THR B CB  1 
ATOM   8165 O OG1 . THR B 1 487 ? -16.26375 18.03203  -31.28532 1.000 70.63750  ? 486 THR B OG1 1 
ATOM   8166 C CG2 . THR B 1 487 ? -17.52090 15.96022  -31.09354 1.000 68.89986  ? 486 THR B CG2 1 
ATOM   8167 N N   . GLU B 1 488 ? -18.64614 20.01056  -33.54902 1.000 72.79737  ? 487 GLU B N   1 
ATOM   8168 C CA  . GLU B 1 488 ? -18.30638 21.40324  -33.79612 1.000 74.90734  ? 487 GLU B CA  1 
ATOM   8169 C C   . GLU B 1 488 ? -17.74572 22.03434  -32.52274 1.000 82.75642  ? 487 GLU B C   1 
ATOM   8170 O O   . GLU B 1 488 ? -18.01294 21.58197  -31.40344 1.000 85.15969  ? 487 GLU B O   1 
ATOM   8171 C CB  . GLU B 1 488 ? -19.53057 22.18387  -34.27999 1.000 69.68348  ? 487 GLU B CB  1 
ATOM   8172 N N   . GLU B 1 489 ? -16.94656 23.08636  -32.70296 1.000 85.21229  ? 488 GLU B N   1 
ATOM   8173 C CA  . GLU B 1 489 ? -16.32754 23.77210  -31.57393 1.000 84.45526  ? 488 GLU B CA  1 
ATOM   8174 C C   . GLU B 1 489 ? -15.90193 25.17091  -31.99904 1.000 86.94042  ? 488 GLU B C   1 
ATOM   8175 O O   . GLU B 1 489 ? -15.33979 25.35428  -33.08610 1.000 76.59199  ? 488 GLU B O   1 
ATOM   8176 C CB  . GLU B 1 489 ? -15.11542 23.00158  -31.03203 1.000 75.45766  ? 488 GLU B CB  1 
ATOM   8177 C CG  . GLU B 1 489 ? -14.52379 23.59257  -29.76412 1.000 77.01635  ? 488 GLU B CG  1 
ATOM   8178 C CD  . GLU B 1 489 ? -14.97864 22.87146  -28.49816 1.000 85.06827  ? 488 GLU B CD  1 
ATOM   8179 O OE1 . GLU B 1 489 ? -14.29551 21.90096  -28.08708 1.000 80.11589  ? 488 GLU B OE1 1 
ATOM   8180 O OE2 . GLU B 1 489 ? -16.01371 23.27857  -27.91533 1.000 84.01097  ? 488 GLU B OE2 1 
ATOM   8181 N N   . ALA B 1 490 ? -16.16331 26.14173  -31.11870 1.000 85.90253  ? 489 ALA B N   1 
ATOM   8182 C CA  . ALA B 1 490 ? -15.80294 27.53322  -31.36227 1.000 77.42024  ? 489 ALA B CA  1 
ATOM   8183 C C   . ALA B 1 490 ? -14.36886 27.65888  -31.86319 1.000 77.71551  ? 489 ALA B C   1 
ATOM   8184 O O   . ALA B 1 490 ? -13.45771 26.97527  -31.38296 1.000 78.12320  ? 489 ALA B O   1 
ATOM   8185 C CB  . ALA B 1 490 ? -15.97555 28.34952  -30.07955 1.000 71.17522  ? 489 ALA B CB  1 
ATOM   8186 N N   . ASP B 1 491 ? -14.17811 28.53822  -32.84856 1.000 71.34447  ? 490 ASP B N   1 
ATOM   8187 C CA  . ASP B 1 491 ? -12.83365 28.81050  -33.33549 1.000 65.90907  ? 490 ASP B CA  1 
ATOM   8188 C C   . ASP B 1 491 ? -11.96508 29.39884  -32.23424 1.000 67.94610  ? 490 ASP B C   1 
ATOM   8189 O O   . ASP B 1 491 ? -10.78873 29.03566  -32.10065 1.000 67.23879  ? 490 ASP B O   1 
ATOM   8190 C CB  . ASP B 1 491 ? -12.89496 29.75658  -34.53216 1.000 70.73396  ? 490 ASP B CB  1 
ATOM   8191 C CG  . ASP B 1 491 ? -12.51890 29.07506  -35.82549 1.000 71.31430  ? 490 ASP B CG  1 
ATOM   8192 O OD1 . ASP B 1 491 ? -11.99562 27.94550  -35.74049 1.000 72.82135  ? 490 ASP B OD1 1 
ATOM   8193 O OD2 . ASP B 1 491 ? -12.73305 29.65985  -36.91539 1.000 68.08932  ? 490 ASP B OD2 1 
ATOM   8194 N N   . GLU B 1 492 ? -12.54007 30.29261  -31.41872 1.000 66.18416  ? 491 GLU B N   1 
ATOM   8195 C CA  . GLU B 1 492 ? -11.77814 31.00531  -30.39944 1.000 60.93105  ? 491 GLU B CA  1 
ATOM   8196 C C   . GLU B 1 492 ? -11.04588 30.06826  -29.44500 1.000 64.92259  ? 491 GLU B C   1 
ATOM   8197 O O   . GLU B 1 492 ? -10.10071 30.51278  -28.78325 1.000 60.46298  ? 491 GLU B O   1 
ATOM   8198 C CB  . GLU B 1 492 ? -12.70272 31.94442  -29.61093 1.000 53.35649  ? 491 GLU B CB  1 
ATOM   8199 N N   . ILE B 1 493 ? -11.44305 28.79036  -29.36480 1.000 66.53336  ? 492 ILE B N   1 
ATOM   8200 C CA  . ILE B 1 493 ? -10.83209 27.83049  -28.44461 1.000 62.36370  ? 492 ILE B CA  1 
ATOM   8201 C C   . ILE B 1 493 ? -10.09031 26.70307  -29.15711 1.000 60.46669  ? 492 ILE B C   1 
ATOM   8202 O O   . ILE B 1 493 ? -9.57863  25.80335  -28.47850 1.000 65.98830  ? 492 ILE B O   1 
ATOM   8203 C CB  . ILE B 1 493 ? -11.85784 27.23807  -27.44663 1.000 61.14384  ? 492 ILE B CB  1 
ATOM   8204 C CG1 . ILE B 1 493 ? -13.18660 26.88341  -28.11364 1.000 69.68365  ? 492 ILE B CG1 1 
ATOM   8205 C CG2 . ILE B 1 493 ? -12.09196 28.15801  -26.25788 1.000 52.52078  ? 492 ILE B CG2 1 
ATOM   8206 C CD1 . ILE B 1 493 ? -14.13301 26.11360  -27.18681 1.000 64.89962  ? 492 ILE B CD1 1 
ATOM   8207 N N   . ARG B 1 494 ? -9.97992  26.72091  -30.48560 1.000 59.55845  ? 493 ARG B N   1 
ATOM   8208 C CA  . ARG B 1 494 ? -9.37296  25.56436  -31.14285 1.000 58.31547  ? 493 ARG B CA  1 
ATOM   8209 C C   . ARG B 1 494 ? -7.91315  25.36982  -30.75688 1.000 57.10984  ? 493 ARG B C   1 
ATOM   8210 O O   . ARG B 1 494 ? -7.41440  24.24122  -30.78831 1.000 56.83388  ? 493 ARG B O   1 
ATOM   8211 C CB  . ARG B 1 494 ? -9.49391  25.66857  -32.65242 1.000 54.18601  ? 493 ARG B CB  1 
ATOM   8212 C CG  . ARG B 1 494 ? -10.79412 25.10973  -33.13389 1.000 62.62810  ? 493 ARG B CG  1 
ATOM   8213 C CD  . ARG B 1 494 ? -10.67563 23.68298  -33.60986 1.000 56.81701  ? 493 ARG B CD  1 
ATOM   8214 N NE  . ARG B 1 494 ? -11.53481 23.51438  -34.77103 1.000 60.55493  ? 493 ARG B NE  1 
ATOM   8215 C CZ  . ARG B 1 494 ? -11.09014 23.45179  -36.01701 1.000 64.52653  ? 493 ARG B CZ  1 
ATOM   8216 N NH1 . ARG B 1 494 ? -9.79167  23.42289  -36.28719 1.000 64.12585  ? 493 ARG B NH1 1 
ATOM   8217 N NH2 . ARG B 1 494 ? -11.96680 23.42070  -37.01671 1.000 64.78865  ? 493 ARG B NH2 1 
ATOM   8218 N N   . ASN B 1 495 ? -7.20784  26.43324  -30.38380 1.000 58.48764  ? 494 ASN B N   1 
ATOM   8219 C CA  . ASN B 1 495 ? -5.81038  26.22648  -30.02646 1.000 52.69907  ? 494 ASN B CA  1 
ATOM   8220 C C   . ASN B 1 495 ? -5.65464  25.40930  -28.75375 1.000 53.51543  ? 494 ASN B C   1 
ATOM   8221 O O   . ASN B 1 495 ? -4.54417  24.93701  -28.47405 1.000 55.57030  ? 494 ASN B O   1 
ATOM   8222 C CB  . ASN B 1 495 ? -5.08087  27.56757  -29.88494 1.000 51.60308  ? 494 ASN B CB  1 
ATOM   8223 C CG  . ASN B 1 495 ? -5.84309  28.57222  -29.03361 1.000 54.82072  ? 494 ASN B CG  1 
ATOM   8224 O OD1 . ASN B 1 495 ? -6.86343  28.25040  -28.41019 1.000 56.21043  ? 494 ASN B OD1 1 
ATOM   8225 N ND2 . ASN B 1 495 ? -5.34682  29.80287  -29.00638 1.000 49.23668  ? 494 ASN B ND2 1 
ATOM   8226 N N   . LEU B 1 496 ? -6.73927  25.20624  -27.99758 1.000 51.69852  ? 495 LEU B N   1 
ATOM   8227 C CA  . LEU B 1 496 ? -6.64985  24.43491  -26.76599 1.000 48.37452  ? 495 LEU B CA  1 
ATOM   8228 C C   . LEU B 1 496 ? -6.19625  23.00371  -27.01623 1.000 53.50738  ? 495 LEU B C   1 
ATOM   8229 O O   . LEU B 1 496 ? -5.69938  22.35983  -26.08580 1.000 53.75808  ? 495 LEU B O   1 
ATOM   8230 C CB  . LEU B 1 496 ? -7.99056  24.45583  -26.03660 1.000 46.44342  ? 495 LEU B CB  1 
ATOM   8231 C CG  . LEU B 1 496 ? -8.34962  25.83844  -25.47188 1.000 50.06293  ? 495 LEU B CG  1 
ATOM   8232 C CD1 . LEU B 1 496 ? -9.68613  25.85008  -24.74399 1.000 52.16804  ? 495 LEU B CD1 1 
ATOM   8233 C CD2 . LEU B 1 496 ? -7.24499  26.37733  -24.57247 1.000 46.90779  ? 495 LEU B CD2 1 
ATOM   8234 N N   . GLY B 1 497 ? -6.33943  22.49533  -28.24759 1.000 49.05875  ? 496 GLY B N   1 
ATOM   8235 C CA  . GLY B 1 497 ? -5.81194  21.18254  -28.57618 1.000 45.78383  ? 496 GLY B CA  1 
ATOM   8236 C C   . GLY B 1 497 ? -4.30210  21.07706  -28.43803 1.000 52.15925  ? 496 GLY B C   1 
ATOM   8237 O O   . GLY B 1 497 ? -3.76829  19.96297  -28.33401 1.000 49.67955  ? 496 GLY B O   1 
ATOM   8238 N N   . VAL B 1 498 ? -3.59748  22.20642  -28.43353 1.000 48.51161  ? 497 VAL B N   1 
ATOM   8239 C CA  . VAL B 1 498 ? -2.16465  22.24047  -28.18068 1.000 48.04172  ? 497 VAL B CA  1 
ATOM   8240 C C   . VAL B 1 498 ? -1.85798  22.93817  -26.86332 1.000 49.36672  ? 497 VAL B C   1 
ATOM   8241 O O   . VAL B 1 498 ? -1.10579  22.42056  -26.03387 1.000 50.90258  ? 497 VAL B O   1 
ATOM   8242 C CB  . VAL B 1 498 ? -1.40681  22.90350  -29.35166 1.000 45.77803  ? 497 VAL B CB  1 
ATOM   8243 C CG1 . VAL B 1 498 ? 0.08272   22.90836  -29.09289 1.000 35.96427  ? 497 VAL B CG1 1 
ATOM   8244 C CG2 . VAL B 1 498 ? -1.69905  22.16488  -30.62816 1.000 50.44582  ? 497 VAL B CG2 1 
ATOM   8245 N N   . LEU B 1 499 ? -2.45456  24.10428  -26.63881 1.000 45.96702  ? 498 LEU B N   1 
ATOM   8246 C CA  . LEU B 1 499 ? -2.17613  24.82772  -25.40404 1.000 50.46662  ? 498 LEU B CA  1 
ATOM   8247 C C   . LEU B 1 499 ? -2.62140  24.01893  -24.19020 1.000 50.49984  ? 498 LEU B C   1 
ATOM   8248 O O   . LEU B 1 499 ? -1.81876  23.71697  -23.30594 1.000 53.08162  ? 498 LEU B O   1 
ATOM   8249 C CB  . LEU B 1 499 ? -2.84853  26.20384  -25.43481 1.000 52.94832  ? 498 LEU B CB  1 
ATOM   8250 C CG  . LEU B 1 499 ? -2.46209  27.12833  -26.60094 1.000 48.33540  ? 498 LEU B CG  1 
ATOM   8251 C CD1 . LEU B 1 499 ? -3.25868  28.40831  -26.52593 1.000 42.92256  ? 498 LEU B CD1 1 
ATOM   8252 C CD2 . LEU B 1 499 ? -0.96394  27.42384  -26.64792 1.000 48.03755  ? 498 LEU B CD2 1 
ATOM   8253 N N   . SER B 1 500 ? -3.89416  23.61609  -24.15099 1.000 50.31340  ? 499 SER B N   1 
ATOM   8254 C CA  . SER B 1 500 ? -4.41438  22.93572  -22.96841 1.000 43.92334  ? 499 SER B CA  1 
ATOM   8255 C C   . SER B 1 500 ? -4.00510  21.46985  -22.91531 1.000 51.27993  ? 499 SER B C   1 
ATOM   8256 O O   . SER B 1 500 ? -3.75619  20.93619  -21.83152 1.000 55.13976  ? 499 SER B O   1 
ATOM   8257 C CB  . SER B 1 500 ? -5.93442  23.05360  -22.91807 1.000 45.67733  ? 499 SER B CB  1 
ATOM   8258 O OG  . SER B 1 500 ? -6.47085  22.21942  -21.90879 1.000 56.54452  ? 499 SER B OG  1 
ATOM   8259 N N   . ASP B 1 501 ? -3.92634  20.80184  -24.06044 1.000 52.52935  ? 500 ASP B N   1 
ATOM   8260 C CA  . ASP B 1 501 ? -3.68373  19.36699  -24.06454 1.000 48.09631  ? 500 ASP B CA  1 
ATOM   8261 C C   . ASP B 1 501 ? -2.21827  18.98844  -24.08736 1.000 51.22290  ? 500 ASP B C   1 
ATOM   8262 O O   . ASP B 1 501 ? -1.88169  17.88904  -23.64625 1.000 57.02660  ? 500 ASP B O   1 
ATOM   8263 C CB  . ASP B 1 501 ? -4.36133  18.71190  -25.25843 1.000 50.12053  ? 500 ASP B CB  1 
ATOM   8264 C CG  . ASP B 1 501 ? -5.82261  18.54954  -25.04127 1.000 57.87559  ? 500 ASP B CG  1 
ATOM   8265 O OD1 . ASP B 1 501 ? -6.27838  19.11227  -24.01313 1.000 57.69697  ? 500 ASP B OD1 1 
ATOM   8266 O OD2 . ASP B 1 501 ? -6.49664  17.87808  -25.87190 1.000 54.78414  ? 500 ASP B OD2 1 
ATOM   8267 N N   . VAL B 1 502 ? -1.33161  19.82714  -24.60312 1.000 46.37894  ? 501 VAL B N   1 
ATOM   8268 C CA  . VAL B 1 502 ? 0.09556   19.53653  -24.59616 1.000 47.54485  ? 501 VAL B CA  1 
ATOM   8269 C C   . VAL B 1 502 ? 0.85131   20.46721  -23.65078 1.000 55.52380  ? 501 VAL B C   1 
ATOM   8270 O O   . VAL B 1 502 ? 1.69007   20.02091  -22.86344 1.000 52.34723  ? 501 VAL B O   1 
ATOM   8271 C CB  . VAL B 1 502 ? 0.68486   19.58994  -26.02036 1.000 38.78490  ? 501 VAL B CB  1 
ATOM   8272 C CG1 . VAL B 1 502 ? 2.09748   19.06043  -26.01251 1.000 39.59772  ? 501 VAL B CG1 1 
ATOM   8273 C CG2 . VAL B 1 502 ? -0.16154  18.78005  -26.95171 1.000 41.75342  ? 501 VAL B CG2 1 
ATOM   8274 N N   . PHE B 1 503 ? 0.56264   21.76832  -23.70840 1.000 54.28132  ? 502 PHE B N   1 
ATOM   8275 C CA  . PHE B 1 503 ? 1.31445   22.70881  -22.88696 1.000 51.87732  ? 502 PHE B CA  1 
ATOM   8276 C C   . PHE B 1 503 ? 0.91837   22.58082  -21.41906 1.000 51.32196  ? 502 PHE B C   1 
ATOM   8277 O O   . PHE B 1 503 ? 1.75280   22.27159  -20.56167 1.000 55.40807  ? 502 PHE B O   1 
ATOM   8278 C CB  . PHE B 1 503 ? 1.10888   24.14748  -23.38413 1.000 55.07037  ? 502 PHE B CB  1 
ATOM   8279 C CG  . PHE B 1 503 ? 1.84959   24.48967  -24.65791 1.000 54.49378  ? 502 PHE B CG  1 
ATOM   8280 C CD1 . PHE B 1 503 ? 2.62749   23.54629  -25.32077 1.000 53.10506  ? 502 PHE B CD1 1 
ATOM   8281 C CD2 . PHE B 1 503 ? 1.75730   25.77682  -25.19559 1.000 56.67875  ? 502 PHE B CD2 1 
ATOM   8282 C CE1 . PHE B 1 503 ? 3.30005   23.88135  -26.49800 1.000 48.05643  ? 502 PHE B CE1 1 
ATOM   8283 C CE2 . PHE B 1 503 ? 2.42565   26.12269  -26.36804 1.000 48.96587  ? 502 PHE B CE2 1 
ATOM   8284 C CZ  . PHE B 1 503 ? 3.19991   25.17337  -27.01500 1.000 45.49068  ? 502 PHE B CZ  1 
ATOM   8285 N N   . ASP B 1 504 ? -0.35548  22.80414  -21.10510 1.000 51.25193  ? 503 ASP B N   1 
ATOM   8286 C CA  . ASP B 1 504 ? -0.74584  22.84424  -19.70282 1.000 52.30948  ? 503 ASP B CA  1 
ATOM   8287 C C   . ASP B 1 504 ? -0.96941  21.47108  -19.08853 1.000 56.28419  ? 503 ASP B C   1 
ATOM   8288 O O   . ASP B 1 504 ? -0.97850  21.35668  -17.85806 1.000 55.33101  ? 503 ASP B O   1 
ATOM   8289 C CB  . ASP B 1 504 ? -2.01729  23.65876  -19.50353 1.000 51.94055  ? 503 ASP B CB  1 
ATOM   8290 C CG  . ASP B 1 504 ? -2.28281  23.93326  -18.03350 1.000 61.54544  ? 503 ASP B CG  1 
ATOM   8291 O OD1 . ASP B 1 504 ? -1.35219  24.44970  -17.36707 1.000 53.67362  ? 503 ASP B OD1 1 
ATOM   8292 O OD2 . ASP B 1 504 ? -3.39075  23.60267  -17.53831 1.000 65.79776  ? 503 ASP B OD2 1 
ATOM   8293 N N   . ASP B 1 505 ? -1.16864  20.43232  -19.89510 1.000 58.21879  ? 504 ASP B N   1 
ATOM   8294 C CA  . ASP B 1 505 ? -1.50347  19.13640  -19.33024 1.000 55.01468  ? 504 ASP B CA  1 
ATOM   8295 C C   . ASP B 1 505 ? -0.31349  18.18290  -19.25249 1.000 53.89205  ? 504 ASP B C   1 
ATOM   8296 O O   . ASP B 1 505 ? -0.39391  17.19128  -18.51941 1.000 56.76148  ? 504 ASP B O   1 
ATOM   8297 C CB  . ASP B 1 505 ? -2.65446  18.49527  -20.12689 1.000 53.40181  ? 504 ASP B CB  1 
ATOM   8298 C CG  . ASP B 1 505 ? -4.05075  18.91100  -19.61286 1.000 66.37732  ? 504 ASP B CG  1 
ATOM   8299 O OD1 . ASP B 1 505 ? -4.17041  19.83949  -18.77508 1.000 62.70709  ? 504 ASP B OD1 1 
ATOM   8300 O OD2 . ASP B 1 505 ? -5.04834  18.30636  -20.06868 1.000 78.01500  ? 504 ASP B OD2 1 
ATOM   8301 N N   . PHE B 1 506 ? 0.79159   18.45645  -19.95593 1.000 45.69889  ? 505 PHE B N   1 
ATOM   8302 C CA  . PHE B 1 506 ? 1.94159   17.55469  -19.88927 1.000 46.68279  ? 505 PHE B CA  1 
ATOM   8303 C C   . PHE B 1 506 ? 3.29671   18.26244  -19.94255 1.000 52.11855  ? 505 PHE B C   1 
ATOM   8304 O O   . PHE B 1 506 ? 4.22577   17.86758  -19.22989 1.000 52.46605  ? 505 PHE B O   1 
ATOM   8305 C CB  . PHE B 1 506 ? 1.88671   16.51382  -21.01239 1.000 46.18883  ? 505 PHE B CB  1 
ATOM   8306 C CG  . PHE B 1 506 ? 3.06868   15.56200  -21.02337 1.000 44.14124  ? 505 PHE B CG  1 
ATOM   8307 C CD1 . PHE B 1 506 ? 3.05772   14.41238  -20.26005 1.000 40.66101  ? 505 PHE B CD1 1 
ATOM   8308 C CD2 . PHE B 1 506 ? 4.18955   15.82656  -21.79608 1.000 44.42698  ? 505 PHE B CD2 1 
ATOM   8309 C CE1 . PHE B 1 506 ? 4.13681   13.54627  -20.26748 1.000 43.39496  ? 505 PHE B CE1 1 
ATOM   8310 C CE2 . PHE B 1 506 ? 5.27128   14.96504  -21.79930 1.000 42.18106  ? 505 PHE B CE2 1 
ATOM   8311 C CZ  . PHE B 1 506 ? 5.24302   13.82390  -21.04189 1.000 43.09452  ? 505 PHE B CZ  1 
ATOM   8312 N N   . LEU B 1 507 ? 3.46012   19.26691  -20.80619 1.000 49.44542  ? 506 LEU B N   1 
ATOM   8313 C CA  . LEU B 1 507 ? 4.76295   19.92123  -20.88073 1.000 47.87258  ? 506 LEU B CA  1 
ATOM   8314 C C   . LEU B 1 507 ? 5.04158   20.76223  -19.63418 1.000 51.83782  ? 506 LEU B C   1 
ATOM   8315 O O   . LEU B 1 507 ? 6.19388   20.85181  -19.18924 1.000 50.36065  ? 506 LEU B O   1 
ATOM   8316 C CB  . LEU B 1 507 ? 4.84440   20.77636  -22.14078 1.000 49.25466  ? 506 LEU B CB  1 
ATOM   8317 C CG  . LEU B 1 507 ? 5.08932   20.08892  -23.48130 1.000 46.86385  ? 506 LEU B CG  1 
ATOM   8318 C CD1 . LEU B 1 507 ? 5.22043   21.16032  -24.53657 1.000 45.03081  ? 506 LEU B CD1 1 
ATOM   8319 C CD2 . LEU B 1 507 ? 6.31969   19.18810  -23.46014 1.000 42.78698  ? 506 LEU B CD2 1 
ATOM   8320 N N   . ARG B 1 508 ? 4.00367   21.37704  -19.05717 1.000 48.23579  ? 507 ARG B N   1 
ATOM   8321 C CA  . ARG B 1 508 ? 4.15172   22.07886  -17.78368 1.000 51.37616  ? 507 ARG B CA  1 
ATOM   8322 C C   . ARG B 1 508 ? 4.87476   21.22408  -16.74462 1.000 52.00190  ? 507 ARG B C   1 
ATOM   8323 O O   . ARG B 1 508 ? 5.70744   21.72844  -15.97657 1.000 50.67644  ? 507 ARG B O   1 
ATOM   8324 C CB  . ARG B 1 508 ? 2.77500   22.49409  -17.26270 1.000 48.20650  ? 507 ARG B CB  1 
ATOM   8325 C CG  . ARG B 1 508 ? 2.76656   22.84835  -15.81390 1.000 45.41295  ? 507 ARG B CG  1 
ATOM   8326 C CD  . ARG B 1 508 ? 1.54285   23.63593  -15.44672 1.000 48.26105  ? 507 ARG B CD  1 
ATOM   8327 N NE  . ARG B 1 508 ? 0.33737   22.84285  -15.62750 1.000 58.97005  ? 507 ARG B NE  1 
ATOM   8328 C CZ  . ARG B 1 508 ? -0.27651  22.16587  -14.66324 1.000 58.81519  ? 507 ARG B CZ  1 
ATOM   8329 N NH1 . ARG B 1 508 ? 0.18409   22.15435  -13.42262 1.000 49.26206  ? 507 ARG B NH1 1 
ATOM   8330 N NH2 . ARG B 1 508 ? -1.38017  21.47914  -14.95562 1.000 58.05672  ? 507 ARG B NH2 1 
ATOM   8331 N N   . HIS B 1 509 ? 4.57081   19.92481  -16.71150 1.000 45.93161  ? 508 HIS B N   1 
ATOM   8332 C CA  . HIS B 1 509 ? 5.23489   19.01606  -15.78942 1.000 43.93219  ? 508 HIS B CA  1 
ATOM   8333 C C   . HIS B 1 509 ? 6.64669   18.64810  -16.24762 1.000 46.20840  ? 508 HIS B C   1 
ATOM   8334 O O   . HIS B 1 509 ? 7.55304   18.49079  -15.42347 1.000 46.29573  ? 508 HIS B O   1 
ATOM   8335 C CB  . HIS B 1 509 ? 4.37138   17.77972  -15.61201 1.000 42.66715  ? 508 HIS B CB  1 
ATOM   8336 C CG  . HIS B 1 509 ? 2.95435   18.10137  -15.28176 1.000 43.49767  ? 508 HIS B CG  1 
ATOM   8337 N ND1 . HIS B 1 509 ? 2.58853   18.70063  -14.09680 1.000 51.37585  ? 508 HIS B ND1 1 
ATOM   8338 C CD2 . HIS B 1 509 ? 1.81245   17.92851  -15.98491 1.000 50.30306  ? 508 HIS B CD2 1 
ATOM   8339 C CE1 . HIS B 1 509 ? 1.27879   18.87536  -14.07845 1.000 52.29054  ? 508 HIS B CE1 1 
ATOM   8340 N NE2 . HIS B 1 509 ? 0.78341   18.41212  -15.21226 1.000 54.81167  ? 508 HIS B NE2 1 
ATOM   8341 N N   . PHE B 1 510 ? 6.87318   18.51762  -17.54883 1.000 51.99128  ? 509 PHE B N   1 
ATOM   8342 C CA  . PHE B 1 510 ? 8.22839   18.23335  -18.00765 1.000 52.27028  ? 509 PHE B CA  1 
ATOM   8343 C C   . PHE B 1 510 ? 9.18096   19.36931  -17.64979 1.000 52.62911  ? 509 PHE B C   1 
ATOM   8344 O O   . PHE B 1 510 ? 10.27225  19.13673  -17.11680 1.000 46.17555  ? 509 PHE B O   1 
ATOM   8345 C CB  . PHE B 1 510 ? 8.23942   17.99049  -19.51301 1.000 45.81411  ? 509 PHE B CB  1 
ATOM   8346 C CG  . PHE B 1 510 ? 9.46618   17.29007  -19.98054 1.000 45.76379  ? 509 PHE B CG  1 
ATOM   8347 C CD1 . PHE B 1 510 ? 10.15663  16.45038  -19.11881 1.000 44.69905  ? 509 PHE B CD1 1 
ATOM   8348 C CD2 . PHE B 1 510 ? 9.94168   17.47174  -21.27059 1.000 43.84825  ? 509 PHE B CD2 1 
ATOM   8349 C CE1 . PHE B 1 510 ? 11.29806  15.79103  -19.54089 1.000 48.92020  ? 509 PHE B CE1 1 
ATOM   8350 C CE2 . PHE B 1 510 ? 11.07646  16.81599  -21.70142 1.000 41.11429  ? 509 PHE B CE2 1 
ATOM   8351 C CZ  . PHE B 1 510 ? 11.76221  15.98034  -20.83948 1.000 45.16984  ? 509 PHE B CZ  1 
ATOM   8352 N N   . ALA B 1 511 ? 8.78857   20.60820  -17.96076 1.000 51.18587  ? 510 ALA B N   1 
ATOM   8353 C CA  . ALA B 1 511 ? 9.67875   21.73839  -17.74695 1.000 51.82388  ? 510 ALA B CA  1 
ATOM   8354 C C   . ALA B 1 511 ? 10.05167  21.84720  -16.27756 1.000 60.31012  ? 510 ALA B C   1 
ATOM   8355 O O   . ALA B 1 511 ? 11.23675  21.97587  -15.93243 1.000 61.56503  ? 510 ALA B O   1 
ATOM   8356 C CB  . ALA B 1 511 ? 9.02242   23.02926  -18.24048 1.000 52.72288  ? 510 ALA B CB  1 
ATOM   8357 N N   . LEU B 1 512 ? 9.04524   21.76430  -15.39499 1.000 56.45566  ? 511 LEU B N   1 
ATOM   8358 C CA  . LEU B 1 512 ? 9.28847   21.86051  -13.95730 1.000 53.62037  ? 511 LEU B CA  1 
ATOM   8359 C C   . LEU B 1 512 ? 10.30096  20.81708  -13.50607 1.000 50.98532  ? 511 LEU B C   1 
ATOM   8360 O O   . LEU B 1 512 ? 11.23605  21.12007  -12.75972 1.000 52.22701  ? 511 LEU B O   1 
ATOM   8361 C CB  . LEU B 1 512 ? 7.97244   21.70490  -13.20059 1.000 46.81295  ? 511 LEU B CB  1 
ATOM   8362 C CG  . LEU B 1 512 ? 7.93068   22.05326  -11.71266 1.000 43.31960  ? 511 LEU B CG  1 
ATOM   8363 C CD1 . LEU B 1 512 ? 6.54636   22.57679  -11.34076 1.000 41.21877  ? 511 LEU B CD1 1 
ATOM   8364 C CD2 . LEU B 1 512 ? 8.28820   20.85646  -10.85341 1.000 46.00274  ? 511 LEU B CD2 1 
ATOM   8365 N N   . LEU B 1 513 ? 10.13526  19.58070  -13.96705 1.000 51.94135  ? 512 LEU B N   1 
ATOM   8366 C CA  . LEU B 1 513 ? 11.11049  18.53656  -13.67226 1.000 52.12438  ? 512 LEU B CA  1 
ATOM   8367 C C   . LEU B 1 513 ? 12.50900  18.94058  -14.13563 1.000 53.02146  ? 512 LEU B C   1 
ATOM   8368 O O   . LEU B 1 513 ? 13.48181  18.83151  -13.38115 1.000 52.78955  ? 512 LEU B O   1 
ATOM   8369 C CB  . LEU B 1 513 ? 10.65781  17.23163  -14.32892 1.000 45.15978  ? 512 LEU B CB  1 
ATOM   8370 C CG  . LEU B 1 513 ? 11.40762  15.93540  -14.07749 1.000 46.62220  ? 512 LEU B CG  1 
ATOM   8371 C CD1 . LEU B 1 513 ? 10.43548  14.81557  -14.27417 1.000 50.47098  ? 512 LEU B CD1 1 
ATOM   8372 C CD2 . LEU B 1 513 ? 12.58880  15.77488  -15.02768 1.000 48.71526  ? 512 LEU B CD2 1 
ATOM   8373 N N   . LEU B 1 514 ? 12.62719  19.40868  -15.38375 1.000 57.04248  ? 513 LEU B N   1 
ATOM   8374 C CA  . LEU B 1 514 ? 13.92434  19.82815  -15.90209 1.000 54.02692  ? 513 LEU B CA  1 
ATOM   8375 C C   . LEU B 1 514 ? 14.41145  21.09168  -15.21652 1.000 54.53020  ? 513 LEU B C   1 
ATOM   8376 O O   . LEU B 1 514 ? 15.62070  21.27741  -15.03019 1.000 53.71818  ? 513 LEU B O   1 
ATOM   8377 C CB  . LEU B 1 514 ? 13.83870  20.05390  -17.40598 1.000 51.47664  ? 513 LEU B CB  1 
ATOM   8378 C CG  . LEU B 1 514 ? 13.51270  18.83821  -18.26570 1.000 49.00366  ? 513 LEU B CG  1 
ATOM   8379 C CD1 . LEU B 1 514 ? 13.10076  19.32920  -19.65032 1.000 48.65067  ? 513 LEU B CD1 1 
ATOM   8380 C CD2 . LEU B 1 514 ? 14.70020  17.87479  -18.34226 1.000 38.51496  ? 513 LEU B CD2 1 
ATOM   8381 N N   . HIS B 1 515 ? 13.49083  21.97142  -14.83977 1.000 53.18893  ? 514 HIS B N   1 
ATOM   8382 C CA  . HIS B 1 515 ? 13.90072  23.19136  -14.16448 1.000 55.81205  ? 514 HIS B CA  1 
ATOM   8383 C C   . HIS B 1 515 ? 14.42850  22.88912  -12.76515 1.000 60.71340  ? 514 HIS B C   1 
ATOM   8384 O O   . HIS B 1 515 ? 15.56261  23.25062  -12.43249 1.000 65.13315  ? 514 HIS B O   1 
ATOM   8385 C CB  . HIS B 1 515 ? 12.73877  24.18080  -14.10937 1.000 52.47464  ? 514 HIS B CB  1 
ATOM   8386 C CG  . HIS B 1 515 ? 13.08292  25.45346  -13.41085 1.000 57.77634  ? 514 HIS B CG  1 
ATOM   8387 N ND1 . HIS B 1 515 ? 14.30093  26.07797  -13.57168 1.000 57.57442  ? 514 HIS B ND1 1 
ATOM   8388 C CD2 . HIS B 1 515 ? 12.37704  26.21850  -12.54714 1.000 57.90319  ? 514 HIS B CD2 1 
ATOM   8389 C CE1 . HIS B 1 515 ? 14.32870  27.17447  -12.83641 1.000 61.17935  ? 514 HIS B CE1 1 
ATOM   8390 N NE2 . HIS B 1 515 ? 13.17329  27.28291  -12.20449 1.000 57.81509  ? 514 HIS B NE2 1 
ATOM   8391 N N   . GLU B 1 516 ? 13.63017  22.19740  -11.93912 1.000 61.14162  ? 515 GLU B N   1 
ATOM   8392 C CA  . GLU B 1 516 ? 13.99659  22.00275  -10.53774 1.000 56.43793  ? 515 GLU B CA  1 
ATOM   8393 C C   . GLU B 1 516 ? 15.17804  21.05462  -10.39071 1.000 53.16505  ? 515 GLU B C   1 
ATOM   8394 O O   . GLU B 1 516 ? 15.96025  21.19202  -9.45230  1.000 59.56750  ? 515 GLU B O   1 
ATOM   8395 C CB  . GLU B 1 516 ? 12.78909  21.50367  -9.73160  1.000 57.32018  ? 515 GLU B CB  1 
ATOM   8396 C CG  . GLU B 1 516 ? 12.36716  20.06924  -10.04277 1.000 69.06840  ? 515 GLU B CG  1 
ATOM   8397 C CD  . GLU B 1 516 ? 12.58691  19.11905  -8.87565  1.000 80.54679  ? 515 GLU B CD  1 
ATOM   8398 O OE1 . GLU B 1 516 ? 12.65666  19.61268  -7.72392  1.000 82.62927  ? 515 GLU B OE1 1 
ATOM   8399 O OE2 . GLU B 1 516 ? 12.73434  17.89274  -9.11881  1.000 72.29000  ? 515 GLU B OE2 1 
ATOM   8400 N N   . SER B 1 517 ? 15.33410  20.09723  -11.29076 1.000 53.51413  ? 516 SER B N   1 
ATOM   8401 C CA  . SER B 1 517 ? 16.52897  19.26657  -11.27016 1.000 53.27328  ? 516 SER B CA  1 
ATOM   8402 C C   . SER B 1 517 ? 17.71654  19.95404  -11.91844 1.000 53.65573  ? 516 SER B C   1 
ATOM   8403 O O   . SER B 1 517 ? 18.77055  19.32233  -12.07288 1.000 48.97006  ? 516 SER B O   1 
ATOM   8404 C CB  . SER B 1 517 ? 16.26134  17.93320  -11.97468 1.000 57.57629  ? 516 SER B CB  1 
ATOM   8405 O OG  . SER B 1 517 ? 16.65778  17.99383  -13.33417 1.000 52.11948  ? 516 SER B OG  1 
ATOM   8406 N N   . GLY B 1 518 ? 17.54941  21.21033  -12.32690 1.000 56.01525  ? 517 GLY B N   1 
ATOM   8407 C CA  . GLY B 1 518 ? 18.60477  21.98271  -12.96595 1.000 49.45765  ? 517 GLY B CA  1 
ATOM   8408 C C   . GLY B 1 518 ? 19.18384  21.35771  -14.21634 1.000 54.31021  ? 517 GLY B C   1 
ATOM   8409 O O   . GLY B 1 518 ? 20.40963  21.34121  -14.38729 1.000 53.47462  ? 517 GLY B O   1 
ATOM   8410 N N   . LEU B 1 519 ? 18.33350  20.83537  -15.09868 1.000 54.74908  ? 518 LEU B N   1 
ATOM   8411 C CA  . LEU B 1 519 ? 18.79944  20.36957  -16.40035 1.000 55.29049  ? 518 LEU B CA  1 
ATOM   8412 C C   . LEU B 1 519 ? 18.56134  21.38876  -17.51629 1.000 57.20008  ? 518 LEU B C   1 
ATOM   8413 O O   . LEU B 1 519 ? 19.39625  21.52285  -18.42265 1.000 52.22381  ? 518 LEU B O   1 
ATOM   8414 C CB  . LEU B 1 519 ? 18.13674  19.03546  -16.75848 1.000 51.63515  ? 518 LEU B CB  1 
ATOM   8415 C CG  . LEU B 1 519 ? 18.66845  17.76466  -16.08807 1.000 50.18592  ? 518 LEU B CG  1 
ATOM   8416 C CD1 . LEU B 1 519 ? 17.59635  16.68261  -16.13833 1.000 51.66022  ? 518 LEU B CD1 1 
ATOM   8417 C CD2 . LEU B 1 519 ? 19.95521  17.26726  -16.73294 1.000 40.93136  ? 518 LEU B CD2 1 
ATOM   8418 N N   . LEU B 1 520 ? 17.44471  22.11289  -17.46494 1.000 48.02568  ? 519 LEU B N   1 
ATOM   8419 C CA  . LEU B 1 520 ? 17.16277  23.18508  -18.40543 1.000 48.18420  ? 519 LEU B CA  1 
ATOM   8420 C C   . LEU B 1 520 ? 16.13886  24.08759  -17.74592 1.000 53.73354  ? 519 LEU B C   1 
ATOM   8421 O O   . LEU B 1 520 ? 15.08892  23.60785  -17.31609 1.000 63.19662  ? 519 LEU B O   1 
ATOM   8422 C CB  . LEU B 1 520 ? 16.62846  22.64030  -19.73381 1.000 61.03066  ? 519 LEU B CB  1 
ATOM   8423 C CG  . LEU B 1 520 ? 16.23904  23.65068  -20.82329 1.000 68.02282  ? 519 LEU B CG  1 
ATOM   8424 C CD1 . LEU B 1 520 ? 17.39720  23.88967  -21.76655 1.000 69.19442  ? 519 LEU B CD1 1 
ATOM   8425 C CD2 . LEU B 1 520 ? 15.00095  23.20172  -21.59330 1.000 60.51758  ? 519 LEU B CD2 1 
ATOM   8426 N N   . THR B 1 521 ? 16.44135  25.37636  -17.65043 1.000 52.60838  ? 520 THR B N   1 
ATOM   8427 C CA  . THR B 1 521 ? 15.57821  26.24754  -16.87325 1.000 55.23302  ? 520 THR B CA  1 
ATOM   8428 C C   . THR B 1 521 ? 14.26658  26.48426  -17.61039 1.000 53.44890  ? 520 THR B C   1 
ATOM   8429 O O   . THR B 1 521 ? 14.12106  26.16962  -18.79094 1.000 55.42557  ? 520 THR B O   1 
ATOM   8430 C CB  . THR B 1 521 ? 16.26969  27.57927  -16.56682 1.000 59.40544  ? 520 THR B CB  1 
ATOM   8431 O OG1 . THR B 1 521 ? 16.11015  28.47819  -17.67328 1.000 65.74091  ? 520 THR B OG1 1 
ATOM   8432 C CG2 . THR B 1 521 ? 17.75588  27.36721  -16.28970 1.000 50.26458  ? 520 THR B CG2 1 
ATOM   8433 N N   . ASP B 1 522 ? 13.29634  27.04023  -16.88081 1.000 52.88619  ? 521 ASP B N   1 
ATOM   8434 C CA  . ASP B 1 522 ? 11.97276  27.25273  -17.45037 1.000 52.44739  ? 521 ASP B CA  1 
ATOM   8435 C C   . ASP B 1 522 ? 12.05004  28.12026  -18.69634 1.000 63.60491  ? 521 ASP B C   1 
ATOM   8436 O O   . ASP B 1 522 ? 11.34467  27.87036  -19.68466 1.000 64.53847  ? 521 ASP B O   1 
ATOM   8437 C CB  . ASP B 1 522 ? 11.05196  27.88722  -16.41410 1.000 48.10779  ? 521 ASP B CB  1 
ATOM   8438 C CG  . ASP B 1 522 ? 9.58781   27.66750  -16.72817 1.000 54.72559  ? 521 ASP B CG  1 
ATOM   8439 O OD1 . ASP B 1 522 ? 9.21434   26.52830  -17.09040 1.000 61.36003  ? 521 ASP B OD1 1 
ATOM   8440 O OD2 . ASP B 1 522 ? 8.80264   28.62841  -16.60806 1.000 52.65290  ? 521 ASP B OD2 1 
ATOM   8441 N N   . GLY B 1 523 ? 12.92873  29.12510  -18.67701 1.000 62.86670  ? 522 GLY B N   1 
ATOM   8442 C CA  . GLY B 1 523 ? 13.01321  30.05345  -19.79416 1.000 56.27495  ? 522 GLY B CA  1 
ATOM   8443 C C   . GLY B 1 523 ? 13.54423  29.40462  -21.05603 1.000 55.88232  ? 522 GLY B C   1 
ATOM   8444 O O   . GLY B 1 523 ? 12.97587  29.58036  -22.13880 1.000 55.36660  ? 522 GLY B O   1 
ATOM   8445 N N   . GLU B 1 524 ? 14.64659  28.65132  -20.93805 1.000 55.06434  ? 523 GLU B N   1 
ATOM   8446 C CA  . GLU B 1 524 ? 15.15397  27.91287  -22.09308 1.000 62.54006  ? 523 GLU B CA  1 
ATOM   8447 C C   . GLU B 1 524 ? 14.20938  26.81112  -22.53758 1.000 63.45665  ? 523 GLU B C   1 
ATOM   8448 O O   . GLU B 1 524 ? 14.36151  26.30290  -23.65261 1.000 62.86731  ? 523 GLU B O   1 
ATOM   8449 C CB  . GLU B 1 524 ? 16.50686  27.27069  -21.81465 1.000 63.06147  ? 523 GLU B CB  1 
ATOM   8450 C CG  . GLU B 1 524 ? 17.62999  28.21266  -21.53693 1.000 65.41941  ? 523 GLU B CG  1 
ATOM   8451 C CD  . GLU B 1 524 ? 18.42798  27.74622  -20.34486 1.000 75.84150  ? 523 GLU B CD  1 
ATOM   8452 O OE1 . GLU B 1 524 ? 17.88406  27.83298  -19.23286 1.000 73.85048  ? 523 GLU B OE1 1 
ATOM   8453 O OE2 . GLU B 1 524 ? 19.57309  27.26667  -20.51036 1.000 81.76758  ? 523 GLU B OE2 1 
ATOM   8454 N N   . PHE B 1 525 ? 13.27327  26.40114  -21.67946 1.000 60.64477  ? 524 PHE B N   1 
ATOM   8455 C CA  . PHE B 1 525 ? 12.26582  25.44025  -22.09987 1.000 58.34861  ? 524 PHE B CA  1 
ATOM   8456 C C   . PHE B 1 525 ? 11.28664  26.09374  -23.06710 1.000 58.23072  ? 524 PHE B C   1 
ATOM   8457 O O   . PHE B 1 525 ? 11.17212  25.68575  -24.23236 1.000 57.71790  ? 524 PHE B O   1 
ATOM   8458 C CB  . PHE B 1 525 ? 11.54239  24.86867  -20.87510 1.000 58.81417  ? 524 PHE B CB  1 
ATOM   8459 C CG  . PHE B 1 525 ? 10.68435  23.67233  -21.18012 1.000 52.05228  ? 524 PHE B CG  1 
ATOM   8460 C CD1 . PHE B 1 525 ? 9.38467   23.83378  -21.65140 1.000 56.29188  ? 524 PHE B CD1 1 
ATOM   8461 C CD2 . PHE B 1 525 ? 11.17309  22.39969  -20.99737 1.000 45.05272  ? 524 PHE B CD2 1 
ATOM   8462 C CE1 . PHE B 1 525 ? 8.59819   22.74384  -21.95003 1.000 51.33107  ? 524 PHE B CE1 1 
ATOM   8463 C CE2 . PHE B 1 525 ? 10.40165  21.31622  -21.27869 1.000 51.16933  ? 524 PHE B CE2 1 
ATOM   8464 C CZ  . PHE B 1 525 ? 9.10598   21.48473  -21.76475 1.000 54.47091  ? 524 PHE B CZ  1 
ATOM   8465 N N   . TRP B 1 526 ? 10.58987  27.13243  -22.60627 1.000 49.41817  ? 525 TRP B N   1 
ATOM   8466 C CA  . TRP B 1 526 ? 9.53835   27.73098  -23.41086 1.000 53.24066  ? 525 TRP B CA  1 
ATOM   8467 C C   . TRP B 1 526 ? 10.08183  28.61986  -24.51973 1.000 60.24830  ? 525 TRP B C   1 
ATOM   8468 O O   . TRP B 1 526 ? 9.33539   28.97909  -25.44155 1.000 54.01474  ? 525 TRP B O   1 
ATOM   8469 C CB  . TRP B 1 526 ? 8.59530   28.50640  -22.50894 1.000 53.13768  ? 525 TRP B CB  1 
ATOM   8470 C CG  . TRP B 1 526 ? 7.95862   27.62071  -21.51735 1.000 59.46843  ? 525 TRP B CG  1 
ATOM   8471 C CD1 . TRP B 1 526 ? 8.22755   27.54559  -20.17901 1.000 59.42082  ? 525 TRP B CD1 1 
ATOM   8472 C CD2 . TRP B 1 526 ? 6.95027   26.65406  -21.78020 1.000 56.93898  ? 525 TRP B CD2 1 
ATOM   8473 N NE1 . TRP B 1 526 ? 7.43262   26.59335  -19.59145 1.000 57.99804  ? 525 TRP B NE1 1 
ATOM   8474 C CE2 . TRP B 1 526 ? 6.63433   26.03539  -20.55473 1.000 57.54421  ? 525 TRP B CE2 1 
ATOM   8475 C CE3 . TRP B 1 526 ? 6.27500   26.25505  -22.93381 1.000 56.15285  ? 525 TRP B CE3 1 
ATOM   8476 C CZ2 . TRP B 1 526 ? 5.66871   25.04287  -20.44998 1.000 57.48362  ? 525 TRP B CZ2 1 
ATOM   8477 C CZ3 . TRP B 1 526 ? 5.31633   25.26891  -22.83069 1.000 59.94896  ? 525 TRP B CZ3 1 
ATOM   8478 C CH2 . TRP B 1 526 ? 5.02107   24.67274  -21.59450 1.000 59.58975  ? 525 TRP B CH2 1 
ATOM   8479 N N   . ALA B 1 527 ? 11.35837  28.99157  -24.45040 1.000 61.84113  ? 526 ALA B N   1 
ATOM   8480 C CA  . ALA B 1 527 ? 12.01676  29.48546  -25.64728 1.000 54.83245  ? 526 ALA B CA  1 
ATOM   8481 C C   . ALA B 1 527 ? 12.14697  28.36194  -26.66674 1.000 58.75873  ? 526 ALA B C   1 
ATOM   8482 O O   . ALA B 1 527 ? 11.72814  28.50797  -27.82304 1.000 65.81982  ? 526 ALA B O   1 
ATOM   8483 C CB  . ALA B 1 527 ? 13.38022  30.08044  -25.29976 1.000 47.70501  ? 526 ALA B CB  1 
ATOM   8484 N N   . THR B 1 528 ? 12.69053  27.21378  -26.24495 1.000 54.82081  ? 527 THR B N   1 
ATOM   8485 C CA  . THR B 1 528 ? 12.84131  26.09495  -27.16923 1.000 51.38295  ? 527 THR B CA  1 
ATOM   8486 C C   . THR B 1 528 ? 11.49361  25.66108  -27.71218 1.000 52.31415  ? 527 THR B C   1 
ATOM   8487 O O   . THR B 1 528 ? 11.37481  25.32458  -28.89521 1.000 56.94701  ? 527 THR B O   1 
ATOM   8488 C CB  . THR B 1 528 ? 13.55120  24.92490  -26.49164 1.000 53.38666  ? 527 THR B CB  1 
ATOM   8489 O OG1 . THR B 1 528 ? 14.68649  25.41264  -25.77542 1.000 63.60853  ? 527 THR B OG1 1 
ATOM   8490 C CG2 . THR B 1 528 ? 14.04829  23.92928  -27.51611 1.000 51.12380  ? 527 THR B CG2 1 
ATOM   8491 N N   . VAL B 1 529 ? 10.45522  25.70836  -26.88039 1.000 50.43606  ? 528 VAL B N   1 
ATOM   8492 C CA  . VAL B 1 529 ? 9.12167   25.36788  -27.36322 1.000 55.42172  ? 528 VAL B CA  1 
ATOM   8493 C C   . VAL B 1 529 ? 8.64751   26.38821  -28.39400 1.000 53.61096  ? 528 VAL B C   1 
ATOM   8494 O O   . VAL B 1 529 ? 8.13718   26.02374  -29.46190 1.000 49.87058  ? 528 VAL B O   1 
ATOM   8495 C CB  . VAL B 1 529 ? 8.13750   25.25852  -26.19036 1.000 53.01241  ? 528 VAL B CB  1 
ATOM   8496 C CG1 . VAL B 1 529 ? 6.73196   24.96118  -26.71896 1.000 50.66440  ? 528 VAL B CG1 1 
ATOM   8497 C CG2 . VAL B 1 529 ? 8.60865   24.20356  -25.22025 1.000 52.91456  ? 528 VAL B CG2 1 
ATOM   8498 N N   . ALA B 1 530 ? 8.80853   27.68160  -28.08688 1.000 54.72194  ? 529 ALA B N   1 
ATOM   8499 C CA  . ALA B 1 530 ? 8.41060   28.73033  -29.02192 1.000 52.96799  ? 529 ALA B CA  1 
ATOM   8500 C C   . ALA B 1 530 ? 9.19744   28.64865  -30.31829 1.000 51.09600  ? 529 ALA B C   1 
ATOM   8501 O O   . ALA B 1 530 ? 8.71397   29.07701  -31.37193 1.000 46.00711  ? 529 ALA B O   1 
ATOM   8502 C CB  . ALA B 1 530 ? 8.59373   30.10561  -28.38779 1.000 51.62048  ? 529 ALA B CB  1 
ATOM   8503 N N   . HIS B 1 531 ? 10.39375  28.08322  -30.27279 1.000 47.31767  ? 530 HIS B N   1 
ATOM   8504 C CA  . HIS B 1 531 ? 11.15355  27.98037  -31.50373 1.000 51.95954  ? 530 HIS B CA  1 
ATOM   8505 C C   . HIS B 1 531 ? 10.75909  26.75400  -32.32837 1.000 58.63899  ? 530 HIS B C   1 
ATOM   8506 O O   . HIS B 1 531 ? 10.67809  26.85471  -33.55623 1.000 58.24793  ? 530 HIS B O   1 
ATOM   8507 C CB  . HIS B 1 531 ? 12.64753  28.01087  -31.18666 1.000 59.12656  ? 530 HIS B CB  1 
ATOM   8508 C CG  . HIS B 1 531 ? 13.25470  29.37589  -31.33642 1.000 70.41560  ? 530 HIS B CG  1 
ATOM   8509 N ND1 . HIS B 1 531 ? 14.18958  29.67995  -32.30413 1.000 67.36924  ? 530 HIS B ND1 1 
ATOM   8510 C CD2 . HIS B 1 531 ? 13.00975  30.53488  -30.67434 1.000 70.20521  ? 530 HIS B CD2 1 
ATOM   8511 C CE1 . HIS B 1 531 ? 14.51776  30.95798  -32.20783 1.000 70.66719  ? 530 HIS B CE1 1 
ATOM   8512 N NE2 . HIS B 1 531 ? 13.81083  31.50113  -31.23288 1.000 58.93045  ? 530 HIS B NE2 1 
ATOM   8513 N N   . SER B 1 532 ? 10.49745  25.59097  -31.70635 1.000 56.47646  ? 531 SER B N   1 
ATOM   8514 C CA  . SER B 1 532 ? 9.93066   24.49410  -32.49726 1.000 50.45289  ? 531 SER B CA  1 
ATOM   8515 C C   . SER B 1 532 ? 8.61433   24.88160  -33.15828 1.000 50.32992  ? 531 SER B C   1 
ATOM   8516 O O   . SER B 1 532 ? 8.35298   24.44770  -34.28448 1.000 52.43454  ? 531 SER B O   1 
ATOM   8517 C CB  . SER B 1 532 ? 9.73128   23.21055  -31.67980 1.000 48.15192  ? 531 SER B CB  1 
ATOM   8518 O OG  . SER B 1 532 ? 10.82075  22.30319  -31.83326 1.000 47.57770  ? 531 SER B OG  1 
ATOM   8519 N N   . VAL B 1 533 ? 7.78456   25.70341  -32.50942 1.000 41.77337  ? 532 VAL B N   1 
ATOM   8520 C CA  . VAL B 1 533 ? 6.49896   26.04060  -33.11890 1.000 44.41969  ? 532 VAL B CA  1 
ATOM   8521 C C   . VAL B 1 533 ? 6.68745   26.94439  -34.33846 1.000 55.50060  ? 532 VAL B C   1 
ATOM   8522 O O   . VAL B 1 533 ? 6.00046   26.78744  -35.35816 1.000 55.91813  ? 532 VAL B O   1 
ATOM   8523 C CB  . VAL B 1 533 ? 5.55486   26.67878  -32.09008 1.000 48.08209  ? 532 VAL B CB  1 
ATOM   8524 C CG1 . VAL B 1 533 ? 4.21441   26.95751  -32.72765 1.000 42.84535  ? 532 VAL B CG1 1 
ATOM   8525 C CG2 . VAL B 1 533 ? 5.39159   25.76874  -30.89139 1.000 50.52252  ? 532 VAL B CG2 1 
ATOM   8526 N N   . ALA B 1 534 ? 7.60623   27.90929  -34.26411 1.000 55.04417  ? 533 ALA B N   1 
ATOM   8527 C CA  . ALA B 1 534 ? 7.87592   28.72347  -35.44570 1.000 48.63240  ? 533 ALA B CA  1 
ATOM   8528 C C   . ALA B 1 534 ? 8.55401   27.89902  -36.54074 1.000 50.95910  ? 533 ALA B C   1 
ATOM   8529 O O   . ALA B 1 534 ? 8.19676   28.00761  -37.71795 1.000 48.70630  ? 533 ALA B O   1 
ATOM   8530 C CB  . ALA B 1 534 ? 8.72308   29.93565  -35.06716 1.000 52.53356  ? 533 ALA B CB  1 
ATOM   8531 N N   . GLU B 1 535 ? 9.53380   27.07020  -36.17104 1.000 50.03340  ? 534 GLU B N   1 
ATOM   8532 C CA  . GLU B 1 535 ? 10.14641  26.15394  -37.12797 1.000 50.52837  ? 534 GLU B CA  1 
ATOM   8533 C C   . GLU B 1 535 ? 9.09034   25.31563  -37.83765 1.000 51.38923  ? 534 GLU B C   1 
ATOM   8534 O O   . GLU B 1 535 ? 9.13323   25.14252  -39.05931 1.000 47.56213  ? 534 GLU B O   1 
ATOM   8535 C CB  . GLU B 1 535 ? 11.15651  25.25160  -36.40429 1.000 57.15623  ? 534 GLU B CB  1 
ATOM   8536 C CG  . GLU B 1 535 ? 11.96479  24.28771  -37.28648 1.000 51.10520  ? 534 GLU B CG  1 
ATOM   8537 C CD  . GLU B 1 535 ? 12.38605  23.01454  -36.54482 1.000 62.04007  ? 534 GLU B CD  1 
ATOM   8538 O OE1 . GLU B 1 535 ? 12.26002  22.97176  -35.30074 1.000 66.75682  ? 534 GLU B OE1 1 
ATOM   8539 O OE2 . GLU B 1 535 ? 12.84543  22.05063  -37.20328 1.000 68.38573  ? 534 GLU B OE2 1 
ATOM   8540 N N   . PHE B 1 536 ? 8.12500   24.78850  -37.08979 1.000 55.18111  ? 535 PHE B N   1 
ATOM   8541 C CA  . PHE B 1 536 ? 7.09936   23.97190  -37.72573 1.000 53.68549  ? 535 PHE B CA  1 
ATOM   8542 C C   . PHE B 1 536 ? 6.17384   24.83151  -38.58253 1.000 54.48388  ? 535 PHE B C   1 
ATOM   8543 O O   . PHE B 1 536 ? 5.89589   24.49430  -39.74382 1.000 48.55215  ? 535 PHE B O   1 
ATOM   8544 C CB  . PHE B 1 536 ? 6.31117   23.19267  -36.67355 1.000 44.50929  ? 535 PHE B CB  1 
ATOM   8545 C CG  . PHE B 1 536 ? 5.14947   22.45074  -37.23779 1.000 45.62529  ? 535 PHE B CG  1 
ATOM   8546 C CD1 . PHE B 1 536 ? 5.32703   21.19820  -37.81126 1.000 46.48267  ? 535 PHE B CD1 1 
ATOM   8547 C CD2 . PHE B 1 536 ? 3.88143   23.01012  -37.22014 1.000 41.06418  ? 535 PHE B CD2 1 
ATOM   8548 C CE1 . PHE B 1 536 ? 4.25767   20.51793  -38.34616 1.000 43.20847  ? 535 PHE B CE1 1 
ATOM   8549 C CE2 . PHE B 1 536 ? 2.81704   22.34217  -37.75794 1.000 40.85983  ? 535 PHE B CE2 1 
ATOM   8550 C CZ  . PHE B 1 536 ? 3.00424   21.09249  -38.31970 1.000 44.99287  ? 535 PHE B CZ  1 
ATOM   8551 N N   . GLN B 1 537 ? 5.68761   25.95201  -38.02579 1.000 51.06170  ? 536 GLN B N   1 
ATOM   8552 C CA  . GLN B 1 537 ? 4.83349   26.84768  -38.80366 1.000 51.20283  ? 536 GLN B CA  1 
ATOM   8553 C C   . GLN B 1 537 ? 5.51918   27.28526  -40.09222 1.000 54.81641  ? 536 GLN B C   1 
ATOM   8554 O O   . GLN B 1 537 ? 4.85524   27.46046  -41.11988 1.000 58.29666  ? 536 GLN B O   1 
ATOM   8555 C CB  . GLN B 1 537 ? 4.42958   28.06907  -37.96671 1.000 45.05743  ? 536 GLN B CB  1 
ATOM   8556 C CG  . GLN B 1 537 ? 3.35738   27.75723  -36.92940 1.000 51.27816  ? 536 GLN B CG  1 
ATOM   8557 C CD  . GLN B 1 537 ? 2.70992   28.98282  -36.31614 1.000 51.25064  ? 536 GLN B CD  1 
ATOM   8558 O OE1 . GLN B 1 537 ? 3.31934   30.04918  -36.22886 1.000 57.19756  ? 536 GLN B OE1 1 
ATOM   8559 N NE2 . GLN B 1 537 ? 1.46336   28.83103  -35.87247 1.000 51.43838  ? 536 GLN B NE2 1 
ATOM   8560 N N   . ALA B 1 538 ? 6.84648   27.44489  -40.06476 1.000 53.41829  ? 537 ALA B N   1 
ATOM   8561 C CA  . ALA B 1 538 ? 7.56742   27.83395  -41.26861 1.000 43.61496  ? 537 ALA B CA  1 
ATOM   8562 C C   . ALA B 1 538 ? 7.60969   26.69000  -42.27436 1.000 49.86774  ? 537 ALA B C   1 
ATOM   8563 O O   . ALA B 1 538 ? 7.49796   26.91582  -43.48354 1.000 58.39746  ? 537 ALA B O   1 
ATOM   8564 C CB  . ALA B 1 538 ? 8.97731   28.30158  -40.91312 1.000 35.66170  ? 537 ALA B CB  1 
ATOM   8565 N N   . ARG B 1 539 ? 7.73509   25.45387  -41.80458 1.000 47.17297  ? 538 ARG B N   1 
ATOM   8566 C CA  . ARG B 1 539 ? 7.80418   24.32519  -42.72966 1.000 48.25455  ? 538 ARG B CA  1 
ATOM   8567 C C   . ARG B 1 539 ? 6.46434   24.00994  -43.39377 1.000 48.09671  ? 538 ARG B C   1 
ATOM   8568 O O   . ARG B 1 539 ? 6.40857   23.13232  -44.26050 1.000 50.36222  ? 538 ARG B O   1 
ATOM   8569 C CB  . ARG B 1 539 ? 8.32866   23.08629  -41.98963 1.000 49.81923  ? 538 ARG B CB  1 
ATOM   8570 C CG  . ARG B 1 539 ? 8.60308   21.89075  -42.85035 1.000 47.53025  ? 538 ARG B CG  1 
ATOM   8571 C CD  . ARG B 1 539 ? 8.95208   20.68359  -42.02908 1.000 52.15650  ? 538 ARG B CD  1 
ATOM   8572 N NE  . ARG B 1 539 ? 9.11004   19.53232  -42.90807 1.000 70.07911  ? 538 ARG B NE  1 
ATOM   8573 C CZ  . ARG B 1 539 ? 9.75608   18.41773  -42.59006 1.000 70.61391  ? 538 ARG B CZ  1 
ATOM   8574 N NH1 . ARG B 1 539 ? 10.31190  18.25382  -41.39612 1.000 63.77636  ? 538 ARG B NH1 1 
ATOM   8575 N NH2 . ARG B 1 539 ? 9.85246   17.44542  -43.49591 1.000 69.00236  ? 538 ARG B NH2 1 
ATOM   8576 N N   . HIS B 1 540 ? 5.38326   24.68264  -43.02406 1.000 44.11654  ? 539 HIS B N   1 
ATOM   8577 C CA  . HIS B 1 540 ? 4.06074   24.36181  -43.55493 1.000 46.09224  ? 539 HIS B CA  1 
ATOM   8578 C C   . HIS B 1 540 ? 3.35399   25.64254  -43.94415 1.000 48.33686  ? 539 HIS B C   1 
ATOM   8579 O O   . HIS B 1 540 ? 2.30741   26.00037  -43.38412 1.000 46.18136  ? 539 HIS B O   1 
ATOM   8580 C CB  . HIS B 1 540 ? 3.24516   23.55245  -42.55229 1.000 49.39476  ? 539 HIS B CB  1 
ATOM   8581 C CG  . HIS B 1 540 ? 3.80916   22.19631  -42.31333 1.000 47.79865  ? 539 HIS B CG  1 
ATOM   8582 N ND1 . HIS B 1 540 ? 3.61796   21.15203  -43.19084 1.000 49.35634  ? 539 HIS B ND1 1 
ATOM   8583 C CD2 . HIS B 1 540 ? 4.61908   21.72837  -41.33495 1.000 48.89791  ? 539 HIS B CD2 1 
ATOM   8584 C CE1 . HIS B 1 540 ? 4.26123   20.08539  -42.74694 1.000 51.74573  ? 539 HIS B CE1 1 
ATOM   8585 N NE2 . HIS B 1 540 ? 4.87688   20.40874  -41.62259 1.000 57.00350  ? 539 HIS B NE2 1 
ATOM   8586 N N   . PRO B 1 541 ? 3.88044   26.33471  -44.95152 1.000 49.51886  ? 540 PRO B N   1 
ATOM   8587 C CA  . PRO B 1 541 ? 3.33361   27.64472  -45.28743 1.000 43.84845  ? 540 PRO B CA  1 
ATOM   8588 C C   . PRO B 1 541 ? 1.95771   27.58408  -45.91074 1.000 40.89237  ? 540 PRO B C   1 
ATOM   8589 O O   . PRO B 1 541 ? 1.19895   28.54170  -45.73721 1.000 46.51695  ? 540 PRO B O   1 
ATOM   8590 C CB  . PRO B 1 541 ? 4.38202   28.21979  -46.23652 1.000 33.26097  ? 540 PRO B CB  1 
ATOM   8591 C CG  . PRO B 1 541 ? 5.04314   27.05990  -46.79733 1.000 40.50700  ? 540 PRO B CG  1 
ATOM   8592 C CD  . PRO B 1 541 ? 5.00539   25.96351  -45.81757 1.000 44.70830  ? 540 PRO B CD  1 
ATOM   8593 N N   . ASP B 1 542 ? 1.57281   26.48823  -46.57127 1.000 41.60942  ? 541 ASP B N   1 
ATOM   8594 C CA  . ASP B 1 542 ? 0.20211   26.42686  -47.08518 1.000 44.21316  ? 541 ASP B CA  1 
ATOM   8595 C C   . ASP B 1 542 ? -0.85624  26.43701  -45.97638 1.000 46.35095  ? 541 ASP B C   1 
ATOM   8596 O O   . ASP B 1 542 ? -2.05122  26.51854  -46.28454 1.000 40.95182  ? 541 ASP B O   1 
ATOM   8597 C CB  . ASP B 1 542 ? 0.00471   25.18691  -47.96289 1.000 44.03793  ? 541 ASP B CB  1 
ATOM   8598 C CG  . ASP B 1 542 ? 0.81273   25.23690  -49.24574 1.000 49.74752  ? 541 ASP B CG  1 
ATOM   8599 O OD1 . ASP B 1 542 ? 1.19277   26.35070  -49.68774 1.000 49.70638  ? 541 ASP B OD1 1 
ATOM   8600 O OD2 . ASP B 1 542 ? 1.08071   24.15048  -49.80645 1.000 50.58214  ? 541 ASP B OD2 1 
ATOM   8601 N N   . LEU B 1 543 ? -0.45721  26.37198  -44.70339 1.000 47.04715  ? 542 LEU B N   1 
ATOM   8602 C CA  . LEU B 1 543 ? -1.39787  26.35813  -43.59106 1.000 47.25678  ? 542 LEU B CA  1 
ATOM   8603 C C   . LEU B 1 543 ? -1.42621  27.66969  -42.81395 1.000 49.96403  ? 542 LEU B C   1 
ATOM   8604 O O   . LEU B 1 543 ? -2.14350  27.76104  -41.80668 1.000 51.37854  ? 542 LEU B O   1 
ATOM   8605 C CB  . LEU B 1 543 ? -1.07570  25.19400  -42.63671 1.000 47.71537  ? 542 LEU B CB  1 
ATOM   8606 C CG  . LEU B 1 543 ? -1.20031  23.77605  -43.20557 1.000 44.68212  ? 542 LEU B CG  1 
ATOM   8607 C CD1 . LEU B 1 543 ? -0.16232  22.85408  -42.60060 1.000 39.23421  ? 542 LEU B CD1 1 
ATOM   8608 C CD2 . LEU B 1 543 ? -2.60366  23.21488  -43.02211 1.000 42.68885  ? 542 LEU B CD2 1 
ATOM   8609 N N   . ALA B 1 544 ? -0.68511  28.69206  -43.26110 1.000 49.46423  ? 543 ALA B N   1 
ATOM   8610 C CA  . ALA B 1 544 ? -0.66263  29.97510  -42.55466 1.000 47.71404  ? 543 ALA B CA  1 
ATOM   8611 C C   . ALA B 1 544 ? -2.04770  30.58304  -42.40034 1.000 46.90789  ? 543 ALA B C   1 
ATOM   8612 O O   . ALA B 1 544 ? -2.30409  31.27383  -41.41086 1.000 48.29442  ? 543 ALA B O   1 
ATOM   8613 C CB  . ALA B 1 544 ? 0.23809   30.96405  -43.27769 1.000 42.73866  ? 543 ALA B CB  1 
ATOM   8614 N N   . ASP B 1 545 ? -2.93577  30.37794  -43.37918 1.000 50.90756  ? 544 ASP B N   1 
ATOM   8615 C CA  . ASP B 1 545 ? -4.31949  30.81057  -43.21902 1.000 48.14581  ? 544 ASP B CA  1 
ATOM   8616 C C   . ASP B 1 545 ? -4.91642  30.21302  -41.95393 1.000 50.56587  ? 544 ASP B C   1 
ATOM   8617 O O   . ASP B 1 545 ? -5.57210  30.91351  -41.17583 1.000 54.29387  ? 544 ASP B O   1 
ATOM   8618 C CB  . ASP B 1 545 ? -5.14434  30.44817  -44.46418 1.000 56.09126  ? 544 ASP B CB  1 
ATOM   8619 C CG  . ASP B 1 545 ? -5.16288  28.91623  -44.76624 1.000 74.40854  ? 544 ASP B CG  1 
ATOM   8620 O OD1 . ASP B 1 545 ? -4.06635  28.30115  -44.91329 1.000 62.35261  ? 544 ASP B OD1 1 
ATOM   8621 O OD2 . ASP B 1 545 ? -6.27921  28.32873  -44.88582 1.000 75.14368  ? 544 ASP B OD2 1 
ATOM   8622 N N   . ARG B 1 546 ? -4.63507  28.93748  -41.69119 1.000 48.61747  ? 545 ARG B N   1 
ATOM   8623 C CA  . ARG B 1 546 ? -5.14530  28.30908  -40.48119 1.000 51.45883  ? 545 ARG B CA  1 
ATOM   8624 C C   . ARG B 1 546 ? -4.36499  28.74832  -39.23844 1.000 53.48139  ? 545 ARG B C   1 
ATOM   8625 O O   . ARG B 1 546 ? -4.95074  28.91476  -38.16107 1.000 48.43773  ? 545 ARG B O   1 
ATOM   8626 C CB  . ARG B 1 546 ? -5.12762  26.79011  -40.64556 1.000 44.18281  ? 545 ARG B CB  1 
ATOM   8627 C CG  . ARG B 1 546 ? -5.94248  26.32788  -41.79814 1.000 46.43379  ? 545 ARG B CG  1 
ATOM   8628 C CD  . ARG B 1 546 ? -6.30167  24.87072  -41.71131 1.000 53.71072  ? 545 ARG B CD  1 
ATOM   8629 N NE  . ARG B 1 546 ? -6.12548  24.19630  -42.99682 1.000 56.98955  ? 545 ARG B NE  1 
ATOM   8630 C CZ  . ARG B 1 546 ? -6.77419  23.10076  -43.37951 1.000 59.72235  ? 545 ARG B CZ  1 
ATOM   8631 N NH1 . ARG B 1 546 ? -7.70332  22.54208  -42.61807 1.000 57.20440  ? 545 ARG B NH1 1 
ATOM   8632 N NH2 . ARG B 1 546 ? -6.49043  22.55593  -44.56287 1.000 56.63281  ? 545 ARG B NH2 1 
ATOM   8633 N N   . PHE B 1 547 ? -3.05141  28.96031  -39.36254 1.000 51.25366  ? 546 PHE B N   1 
ATOM   8634 C CA  . PHE B 1 547 ? -2.26130  29.37024  -38.20433 1.000 49.58022  ? 546 PHE B CA  1 
ATOM   8635 C C   . PHE B 1 547 ? -2.71041  30.70976  -37.62718 1.000 55.39129  ? 546 PHE B C   1 
ATOM   8636 O O   . PHE B 1 547 ? -2.41577  30.99761  -36.46005 1.000 56.93742  ? 546 PHE B O   1 
ATOM   8637 C CB  . PHE B 1 547 ? -0.78104  29.43697  -38.57476 1.000 45.37761  ? 546 PHE B CB  1 
ATOM   8638 C CG  . PHE B 1 547 ? -0.15064  28.09757  -38.77713 1.000 43.38488  ? 546 PHE B CG  1 
ATOM   8639 C CD1 . PHE B 1 547 ? -0.53185  27.01872  -38.00245 1.000 44.93718  ? 546 PHE B CD1 1 
ATOM   8640 C CD2 . PHE B 1 547 ? 0.81849   27.91398  -39.74740 1.000 45.75431  ? 546 PHE B CD2 1 
ATOM   8641 C CE1 . PHE B 1 547 ? 0.03991   25.78340  -38.18719 1.000 45.60351  ? 546 PHE B CE1 1 
ATOM   8642 C CE2 . PHE B 1 547 ? 1.40023   26.68389  -39.94126 1.000 45.66766  ? 546 PHE B CE2 1 
ATOM   8643 C CZ  . PHE B 1 547 ? 1.01199   25.61236  -39.15934 1.000 48.69184  ? 546 PHE B CZ  1 
ATOM   8644 N N   . ASP B 1 548 ? -3.40222  31.53936  -38.41492 1.000 59.64796  ? 547 ASP B N   1 
ATOM   8645 C CA  . ASP B 1 548 ? -3.93214  32.80170  -37.91260 1.000 59.08672  ? 547 ASP B CA  1 
ATOM   8646 C C   . ASP B 1 548 ? -5.35097  32.66185  -37.38293 1.000 59.62844  ? 547 ASP B C   1 
ATOM   8647 O O   . ASP B 1 548 ? -5.74684  33.41199  -36.48356 1.000 69.13909  ? 547 ASP B O   1 
ATOM   8648 C CB  . ASP B 1 548 ? -3.88724  33.87273  -39.00432 1.000 51.33684  ? 547 ASP B CB  1 
ATOM   8649 C CG  . ASP B 1 548 ? -2.46122  34.27734  -39.36880 1.000 69.96269  ? 547 ASP B CG  1 
ATOM   8650 O OD1 . ASP B 1 548 ? -1.55978  34.23869  -38.49124 1.000 65.69611  ? 547 ASP B OD1 1 
ATOM   8651 O OD2 . ASP B 1 548 ? -2.24195  34.63519  -40.54808 1.000 80.49650  ? 547 ASP B OD2 1 
ATOM   8652 N N   . GLN B 1 549 ? -6.12055  31.71510  -37.91828 1.000 54.92557  ? 548 GLN B N   1 
ATOM   8653 C CA  . GLN B 1 549 ? -7.43107  31.39712  -37.35460 1.000 55.93983  ? 548 GLN B CA  1 
ATOM   8654 C C   . GLN B 1 549 ? -7.32504  30.88510  -35.91622 1.000 58.70666  ? 548 GLN B C   1 
ATOM   8655 O O   . GLN B 1 549 ? -8.21415  31.13090  -35.09418 1.000 57.97829  ? 548 GLN B O   1 
ATOM   8656 C CB  . GLN B 1 549 ? -8.10568  30.33040  -38.21319 1.000 57.36830  ? 548 GLN B CB  1 
ATOM   8657 C CG  . GLN B 1 549 ? -9.19281  30.76768  -39.14365 1.000 57.08342  ? 548 GLN B CG  1 
ATOM   8658 C CD  . GLN B 1 549 ? -9.83472  29.56056  -39.79605 1.000 65.84005  ? 548 GLN B CD  1 
ATOM   8659 O OE1 . GLN B 1 549 ? -10.74046 28.94576  -39.22521 1.000 68.11134  ? 548 GLN B OE1 1 
ATOM   8660 N NE2 . GLN B 1 549 ? -9.34231  29.18529  -40.98080 1.000 67.22533  ? 548 GLN B NE2 1 
ATOM   8661 N N   . TRP B 1 550 ? -6.26584  30.12658  -35.60855 1.000 56.71851  ? 549 TRP B N   1 
ATOM   8662 C CA  . TRP B 1 550 ? -6.17083  29.32126  -34.38648 1.000 48.71297  ? 549 TRP B CA  1 
ATOM   8663 C C   . TRP B 1 550 ? -4.77002  29.53684  -33.82740 1.000 50.29616  ? 549 TRP B C   1 
ATOM   8664 O O   . TRP B 1 550 ? -3.87253  28.73269  -34.07816 1.000 52.11909  ? 549 TRP B O   1 
ATOM   8665 C CB  . TRP B 1 550 ? -6.42775  27.84606  -34.67033 1.000 49.77576  ? 549 TRP B CB  1 
ATOM   8666 C CG  . TRP B 1 550 ? -7.69864  27.55319  -35.40596 1.000 53.15419  ? 549 TRP B CG  1 
ATOM   8667 C CD1 . TRP B 1 550 ? -8.93765  28.04265  -35.12121 1.000 57.72806  ? 549 TRP B CD1 1 
ATOM   8668 C CD2 . TRP B 1 550 ? -7.85938  26.69184  -36.54579 1.000 56.22653  ? 549 TRP B CD2 1 
ATOM   8669 N NE1 . TRP B 1 550 ? -9.85642  27.54323  -36.00931 1.000 59.37911  ? 549 TRP B NE1 1 
ATOM   8670 C CE2 . TRP B 1 550 ? -9.22189  26.71312  -36.89381 1.000 55.78584  ? 549 TRP B CE2 1 
ATOM   8671 C CE3 . TRP B 1 550 ? -6.98017  25.90703  -37.30661 1.000 59.67504  ? 549 TRP B CE3 1 
ATOM   8672 C CZ2 . TRP B 1 550 ? -9.72874  25.98646  -37.96504 1.000 56.69831  ? 549 TRP B CZ2 1 
ATOM   8673 C CZ3 . TRP B 1 550 ? -7.48519  25.17936  -38.37267 1.000 50.31155  ? 549 TRP B CZ3 1 
ATOM   8674 C CH2 . TRP B 1 550 ? -8.84647  25.22483  -38.68823 1.000 57.88970  ? 549 TRP B CH2 1 
ATOM   8675 N N   . ASP B 1 551 ? -4.60143  30.59867  -33.04341 1.000 54.43714  ? 550 ASP B N   1 
ATOM   8676 C CA  . ASP B 1 551 ? -3.27885  31.15022  -32.75558 1.000 48.56158  ? 550 ASP B CA  1 
ATOM   8677 C C   . ASP B 1 551 ? -2.55820  30.35608  -31.67234 1.000 49.48093  ? 550 ASP B C   1 
ATOM   8678 O O   . ASP B 1 551 ? -2.89444  30.44601  -30.48503 1.000 48.70745  ? 550 ASP B O   1 
ATOM   8679 C CB  . ASP B 1 551 ? -3.39968  32.60932  -32.34288 1.000 48.05634  ? 550 ASP B CB  1 
ATOM   8680 C CG  . ASP B 1 551 ? -2.11272  33.36132  -32.53477 1.000 50.62529  ? 550 ASP B CG  1 
ATOM   8681 O OD1 . ASP B 1 551 ? -1.25363  32.87054  -33.32204 1.000 48.30406  ? 550 ASP B OD1 1 
ATOM   8682 O OD2 . ASP B 1 551 ? -1.97320  34.43743  -31.89849 1.000 48.65549  ? 550 ASP B OD2 1 
ATOM   8683 N N   . LEU B 1 552 ? -1.52190  29.62357  -32.07378 1.000 47.27816  ? 551 LEU B N   1 
ATOM   8684 C CA  . LEU B 1 552 ? -0.63852  29.02036  -31.09106 1.000 46.43044  ? 551 LEU B CA  1 
ATOM   8685 C C   . LEU B 1 552 ? 0.09206   30.07468  -30.26206 1.000 49.82715  ? 551 LEU B C   1 
ATOM   8686 O O   . LEU B 1 552 ? 0.57250   29.76680  -29.16372 1.000 52.29462  ? 551 LEU B O   1 
ATOM   8687 C CB  . LEU B 1 552 ? 0.34580   28.08555  -31.79803 1.000 44.15128  ? 551 LEU B CB  1 
ATOM   8688 C CG  . LEU B 1 552 ? -0.31625  26.86933  -32.46521 1.000 46.55235  ? 551 LEU B CG  1 
ATOM   8689 C CD1 . LEU B 1 552 ? 0.70212   26.00480  -33.17070 1.000 53.53516  ? 551 LEU B CD1 1 
ATOM   8690 C CD2 . LEU B 1 552 ? -1.11068  26.01924  -31.47970 1.000 45.03104  ? 551 LEU B CD2 1 
ATOM   8691 N N   . PHE B 1 553 ? 0.15692   31.31773  -30.74030 1.000 49.07471  ? 552 PHE B N   1 
ATOM   8692 C CA  . PHE B 1 553 ? 0.84930   32.38717  -30.03544 1.000 46.51906  ? 552 PHE B CA  1 
ATOM   8693 C C   . PHE B 1 553 ? -0.10581  33.36985  -29.37589 1.000 43.01639  ? 552 PHE B C   1 
ATOM   8694 O O   . PHE B 1 553 ? 0.29949   34.49038  -29.07556 1.000 52.07744  ? 552 PHE B O   1 
ATOM   8695 C CB  . PHE B 1 553 ? 1.79033   33.14132  -30.97956 1.000 47.46060  ? 552 PHE B CB  1 
ATOM   8696 C CG  . PHE B 1 553 ? 2.97087   32.33825  -31.42622 1.000 48.20972  ? 552 PHE B CG  1 
ATOM   8697 C CD1 . PHE B 1 553 ? 4.14100   32.33249  -30.68919 1.000 51.35730  ? 552 PHE B CD1 1 
ATOM   8698 C CD2 . PHE B 1 553 ? 2.90964   31.58200  -32.57736 1.000 48.16678  ? 552 PHE B CD2 1 
ATOM   8699 C CE1 . PHE B 1 553 ? 5.23422   31.57923  -31.09036 1.000 49.65622  ? 552 PHE B CE1 1 
ATOM   8700 C CE2 . PHE B 1 553 ? 3.99280   30.83155  -32.98167 1.000 52.63610  ? 552 PHE B CE2 1 
ATOM   8701 C CZ  . PHE B 1 553 ? 5.15816   30.82386  -32.23263 1.000 50.50869  ? 552 PHE B CZ  1 
ATOM   8702 N N   . ALA B 1 554 ? -1.35525  32.98692  -29.13303 1.000 41.77056  ? 553 ALA B N   1 
ATOM   8703 C CA  . ALA B 1 554 ? -2.26615  33.89845  -28.44484 1.000 47.01429  ? 553 ALA B CA  1 
ATOM   8704 C C   . ALA B 1 554 ? -1.70766  34.30925  -27.07693 1.000 56.35487  ? 553 ALA B C   1 
ATOM   8705 O O   . ALA B 1 554 ? -0.89082  33.59467  -26.48297 1.000 54.02042  ? 553 ALA B O   1 
ATOM   8706 C CB  . ALA B 1 554 ? -3.63914  33.25957  -28.26381 1.000 47.55175  ? 553 ALA B CB  1 
ATOM   8707 N N   . PRO B 1 555 ? -2.12078  35.47288  -26.55339 1.000 59.09153  ? 554 PRO B N   1 
ATOM   8708 C CA  . PRO B 1 555 ? -1.67433  35.87086  -25.21114 1.000 62.19812  ? 554 PRO B CA  1 
ATOM   8709 C C   . PRO B 1 555 ? -2.17638  34.93238  -24.11814 1.000 60.94557  ? 554 PRO B C   1 
ATOM   8710 O O   . PRO B 1 555 ? -1.36053  34.30071  -23.44228 1.000 60.77365  ? 554 PRO B O   1 
ATOM   8711 C CB  . PRO B 1 555 ? -2.24943  37.28669  -25.05616 1.000 54.61199  ? 554 PRO B CB  1 
ATOM   8712 C CG  . PRO B 1 555 ? -2.47974  37.75066  -26.44448 1.000 44.82394  ? 554 PRO B CG  1 
ATOM   8713 C CD  . PRO B 1 555 ? -2.92228  36.53198  -27.18153 1.000 52.20535  ? 554 PRO B CD  1 
ATOM   8714 N N   . THR B 1 556 ? -3.49319  34.81923  -23.92317 1.000 60.75066  ? 555 THR B N   1 
ATOM   8715 C CA  . THR B 1 556 ? -4.03915  33.95000  -22.88897 1.000 60.42113  ? 555 THR B CA  1 
ATOM   8716 C C   . THR B 1 556 ? -5.00074  32.93097  -23.47842 1.000 59.63319  ? 555 THR B C   1 
ATOM   8717 O O   . THR B 1 556 ? -5.68529  33.18995  -24.47273 1.000 65.37510  ? 555 THR B O   1 
ATOM   8718 C CB  . THR B 1 556 ? -4.79040  34.72893  -21.79630 1.000 61.24366  ? 555 THR B CB  1 
ATOM   8719 O OG1 . THR B 1 556 ? -6.14053  34.98951  -22.21752 1.000 66.20515  ? 555 THR B OG1 1 
ATOM   8720 C CG2 . THR B 1 556 ? -4.09542  36.02475  -21.51008 1.000 53.77787  ? 555 THR B CG2 1 
ATOM   8721 N N   . PHE B 1 557 ? -5.04596  31.77244  -22.83902 1.000 57.43361  ? 556 PHE B N   1 
ATOM   8722 C CA  . PHE B 1 557 ? -6.08641  30.78279  -23.03158 1.000 55.78799  ? 556 PHE B CA  1 
ATOM   8723 C C   . PHE B 1 557 ? -6.66756  30.43458  -21.67060 1.000 56.58947  ? 556 PHE B C   1 
ATOM   8724 O O   . PHE B 1 557 ? -6.00025  30.60601  -20.64427 1.000 50.35573  ? 556 PHE B O   1 
ATOM   8725 C CB  . PHE B 1 557 ? -5.55148  29.51719  -23.72165 1.000 50.48983  ? 556 PHE B CB  1 
ATOM   8726 C CG  . PHE B 1 557 ? -4.42209  28.84774  -22.99205 1.000 51.34738  ? 556 PHE B CG  1 
ATOM   8727 C CD1 . PHE B 1 557 ? -3.12120  29.30653  -23.12675 1.000 49.46853  ? 556 PHE B CD1 1 
ATOM   8728 C CD2 . PHE B 1 557 ? -4.65958  27.74575  -22.17978 1.000 52.86133  ? 556 PHE B CD2 1 
ATOM   8729 C CE1 . PHE B 1 557 ? -2.07124  28.67862  -22.45802 1.000 52.92812  ? 556 PHE B CE1 1 
ATOM   8730 C CE2 . PHE B 1 557 ? -3.62349  27.11463  -21.50392 1.000 53.17783  ? 556 PHE B CE2 1 
ATOM   8731 C CZ  . PHE B 1 557 ? -2.32458  27.57904  -21.64307 1.000 54.81554  ? 556 PHE B CZ  1 
ATOM   8732 N N   . PRO B 1 558 ? -7.91040  29.96885  -21.63116 1.000 55.51864  ? 557 PRO B N   1 
ATOM   8733 C CA  . PRO B 1 558 ? -8.53312  29.63189  -20.34602 1.000 53.47557  ? 557 PRO B CA  1 
ATOM   8734 C C   . PRO B 1 558 ? -7.88498  28.40871  -19.73051 1.000 57.66237  ? 557 PRO B C   1 
ATOM   8735 O O   . PRO B 1 558 ? -7.13521  27.67348  -20.37158 1.000 57.26236  ? 557 PRO B O   1 
ATOM   8736 C CB  . PRO B 1 558 ? -9.98676  29.34958  -20.71240 1.000 58.91920  ? 557 PRO B CB  1 
ATOM   8737 C CG  . PRO B 1 558 ? -9.95433  29.00834  -22.16288 1.000 53.88734  ? 557 PRO B CG  1 
ATOM   8738 C CD  . PRO B 1 558 ? -8.82375  29.77222  -22.76641 1.000 49.66861  ? 557 PRO B CD  1 
ATOM   8739 N N   . ALA B 1 559 ? -8.18539  28.19816  -18.45443 1.000 67.12065  ? 558 ALA B N   1 
ATOM   8740 C CA  . ALA B 1 559 ? -7.71053  27.02230  -17.74240 1.000 59.35550  ? 558 ALA B CA  1 
ATOM   8741 C C   . ALA B 1 559 ? -8.74897  25.91500  -17.82494 1.000 59.49326  ? 558 ALA B C   1 
ATOM   8742 O O   . ALA B 1 559 ? -9.93857  26.17110  -18.03625 1.000 63.54935  ? 558 ALA B O   1 
ATOM   8743 C CB  . ALA B 1 559 ? -7.41291  27.35597  -16.28382 1.000 56.19947  ? 558 ALA B CB  1 
ATOM   8744 N N   . ILE B 1 560 ? -8.28060  24.67524  -17.70048 1.000 57.45569  ? 559 ILE B N   1 
ATOM   8745 C CA  . ILE B 1 560 ? -9.14555  23.51039  -17.53350 1.000 55.40845  ? 559 ILE B CA  1 
ATOM   8746 C C   . ILE B 1 560 ? -8.61666  22.76994  -16.31414 1.000 56.22512  ? 559 ILE B C   1 
ATOM   8747 O O   . ILE B 1 560 ? -7.56250  22.12771  -16.37862 1.000 65.05979  ? 559 ILE B O   1 
ATOM   8748 C CB  . ILE B 1 560 ? -9.16835  22.60055  -18.76834 1.000 54.57218  ? 559 ILE B CB  1 
ATOM   8749 C CG1 . ILE B 1 560 ? -10.01451 23.21277  -19.87756 1.000 55.85271  ? 559 ILE B CG1 1 
ATOM   8750 C CG2 . ILE B 1 560 ? -9.76564  21.27254  -18.43039 1.000 51.00059  ? 559 ILE B CG2 1 
ATOM   8751 C CD1 . ILE B 1 560 ? -9.63393  22.70838  -21.25256 1.000 52.26463  ? 559 ILE B CD1 1 
ATOM   8752 N N   . HIS B 1 561 ? -9.32925  22.87293  -15.20107 1.000 56.81960  ? 560 HIS B N   1 
ATOM   8753 C CA  . HIS B 1 561 ? -8.82005  22.41183  -13.91077 1.000 62.20776  ? 560 HIS B CA  1 
ATOM   8754 C C   . HIS B 1 561 ? -9.11951  20.92961  -13.72404 1.000 59.20615  ? 560 HIS B C   1 
ATOM   8755 O O   . HIS B 1 561 ? -10.16504 20.55584  -13.19596 1.000 57.61434  ? 560 HIS B O   1 
ATOM   8756 C CB  . HIS B 1 561 ? -9.43340  23.23646  -12.79099 1.000 64.00624  ? 560 HIS B CB  1 
ATOM   8757 C CG  . HIS B 1 561 ? -9.00836  24.67468  -12.78452 1.000 65.45905  ? 560 HIS B CG  1 
ATOM   8758 N ND1 . HIS B 1 561 ? -9.86869  25.70104  -12.45368 1.000 61.52382  ? 560 HIS B ND1 1 
ATOM   8759 C CD2 . HIS B 1 561 ? -7.81745  25.25736  -13.06613 1.000 60.03613  ? 560 HIS B CD2 1 
ATOM   8760 C CE1 . HIS B 1 561 ? -9.22776  26.85291  -12.53364 1.000 61.55020  ? 560 HIS B CE1 1 
ATOM   8761 N NE2 . HIS B 1 561 ? -7.98171  26.61115  -12.90078 1.000 64.10810  ? 560 HIS B NE2 1 
ATOM   8762 N N   . MET B 1 562 ? -8.16940  20.08199  -14.14053 1.000 61.41201  ? 561 MET B N   1 
ATOM   8763 C CA  . MET B 1 562 ? -8.31323  18.62687  -14.06147 1.000 60.17638  ? 561 MET B CA  1 
ATOM   8764 C C   . MET B 1 562 ? -8.95408  18.15739  -12.75769 1.000 59.73432  ? 561 MET B C   1 
ATOM   8765 O O   . MET B 1 562 ? -9.92750  17.40164  -12.77158 1.000 59.96613  ? 561 MET B O   1 
ATOM   8766 C CB  . MET B 1 562 ? -6.93983  17.96592  -14.20258 1.000 62.39099  ? 561 MET B CB  1 
ATOM   8767 C CG  . MET B 1 562 ? -6.46313  17.63114  -15.61493 1.000 68.54924  ? 561 MET B CG  1 
ATOM   8768 S SD  . MET B 1 562 ? -7.69061  17.21555  -16.85015 1.000 74.52580  ? 561 MET B SD  1 
ATOM   8769 C CE  . MET B 1 562 ? -7.62036  18.67384  -17.87797 1.000 72.38337  ? 561 MET B CE  1 
ATOM   8770 N N   . ASN B 1 563 ? -8.41464  18.60715  -11.61618 1.000 63.39934  ? 562 ASN B N   1 
ATOM   8771 C CA  . ASN B 1 563 ? -8.75235  18.01244  -10.32291 1.000 52.19032  ? 562 ASN B CA  1 
ATOM   8772 C C   . ASN B 1 563 ? -10.13114 18.43356  -9.83928  1.000 57.39736  ? 562 ASN B C   1 
ATOM   8773 O O   . ASN B 1 563 ? -10.91307 17.59696  -9.38205  1.000 64.39127  ? 562 ASN B O   1 
ATOM   8774 C CB  . ASN B 1 563 ? -7.70968  18.38993  -9.29260  1.000 48.25269  ? 562 ASN B CB  1 
ATOM   8775 C CG  . ASN B 1 563 ? -6.53131  17.45245  -9.29457  1.000 56.83859  ? 562 ASN B CG  1 
ATOM   8776 O OD1 . ASN B 1 563 ? -6.67542  16.24193  -9.12464  1.000 56.47140  ? 562 ASN B OD1 1 
ATOM   8777 N ND2 . ASN B 1 563 ? -5.34622  18.00945  -9.47532  1.000 57.14468  ? 562 ASN B ND2 1 
ATOM   8778 N N   . ARG B 1 564 ? -10.44055 19.72969  -9.89159  1.000 57.34437  ? 563 ARG B N   1 
ATOM   8779 C CA  . ARG B 1 564 ? -11.80319 20.16053  -9.58975  1.000 58.58520  ? 563 ARG B CA  1 
ATOM   8780 C C   . ARG B 1 564 ? -12.82832 19.39960  -10.42595 1.000 65.65095  ? 563 ARG B C   1 
ATOM   8781 O O   . ARG B 1 564 ? -13.92527 19.08179  -9.94920  1.000 67.20945  ? 563 ARG B O   1 
ATOM   8782 C CB  . ARG B 1 564 ? -11.95099 21.65924  -9.82271  1.000 56.64784  ? 563 ARG B CB  1 
ATOM   8783 C CG  . ARG B 1 564 ? -10.68390 22.45093  -9.65423  1.000 63.31474  ? 563 ARG B CG  1 
ATOM   8784 C CD  . ARG B 1 564 ? -10.93802 23.92888  -9.95011  1.000 65.83273  ? 563 ARG B CD  1 
ATOM   8785 N NE  . ARG B 1 564 ? -12.13330 24.44926  -9.29476  1.000 70.48286  ? 563 ARG B NE  1 
ATOM   8786 C CZ  . ARG B 1 564 ? -12.12803 25.36057  -8.33123  1.000 72.77417  ? 563 ARG B CZ  1 
ATOM   8787 N NH1 . ARG B 1 564 ? -10.99883 25.93149  -7.92235  1.000 66.49496  ? 563 ARG B NH1 1 
ATOM   8788 N NH2 . ARG B 1 564 ? -13.28465 25.71908  -7.77539  1.000 68.86957  ? 563 ARG B NH2 1 
ATOM   8789 N N   . LEU B 1 565 ? -12.48510 19.10350  -11.67964 1.000 68.47374  ? 564 LEU B N   1 
ATOM   8790 C CA  . LEU B 1 565 ? -13.34596 18.29280  -12.53512 1.000 71.42442  ? 564 LEU B CA  1 
ATOM   8791 C C   . LEU B 1 565 ? -13.64780 16.94269  -11.89454 1.000 72.35795  ? 564 LEU B C   1 
ATOM   8792 O O   . LEU B 1 565 ? -14.81145 16.59869  -11.65151 1.000 75.97510  ? 564 LEU B O   1 
ATOM   8793 C CB  . LEU B 1 565 ? -12.67530 18.10164  -13.89439 1.000 71.85162  ? 564 LEU B CB  1 
ATOM   8794 C CG  . LEU B 1 565 ? -13.47667 17.59629  -15.08193 1.000 70.01217  ? 564 LEU B CG  1 
ATOM   8795 C CD1 . LEU B 1 565 ? -14.61221 18.54585  -15.38763 1.000 67.01759  ? 564 LEU B CD1 1 
ATOM   8796 C CD2 . LEU B 1 565 ? -12.53204 17.43794  -16.26398 1.000 70.60432  ? 564 LEU B CD2 1 
ATOM   8797 N N   . GLN B 1 566 ? -12.60219 16.15788  -11.61628 1.000 68.45810  ? 565 GLN B N   1 
ATOM   8798 C CA  . GLN B 1 566 ? -12.81931 14.82298  -11.07400 1.000 72.86247  ? 565 GLN B CA  1 
ATOM   8799 C C   . GLN B 1 566 ? -13.62529 14.87137  -9.78498  1.000 73.86716  ? 565 GLN B C   1 
ATOM   8800 O O   . GLN B 1 566 ? -14.35718 13.92137  -9.48335  1.000 80.24307  ? 565 GLN B O   1 
ATOM   8801 C CB  . GLN B 1 566 ? -11.48232 14.11514  -10.84421 1.000 64.98210  ? 565 GLN B CB  1 
ATOM   8802 C CG  . GLN B 1 566 ? -11.60757 12.61105  -10.63810 1.000 72.13431  ? 565 GLN B CG  1 
ATOM   8803 C CD  . GLN B 1 566 ? -10.37774 11.99387  -9.97588  1.000 71.09908  ? 565 GLN B CD  1 
ATOM   8804 O OE1 . GLN B 1 566 ? -9.36391  12.66116  -9.77498  1.000 69.12692  ? 565 GLN B OE1 1 
ATOM   8805 N NE2 . GLN B 1 566 ? -10.45862 10.70484  -9.65865  1.000 67.54943  ? 565 GLN B NE2 1 
ATOM   8806 N N   . LEU B 1 567 ? -13.54984 15.98391  -9.04424  1.000 64.63264  ? 566 LEU B N   1 
ATOM   8807 C CA  . LEU B 1 567 ? -14.15424 16.07752  -7.71840  1.000 68.94109  ? 566 LEU B CA  1 
ATOM   8808 C C   . LEU B 1 567 ? -15.66740 16.26878  -7.79436  1.000 78.89978  ? 566 LEU B C   1 
ATOM   8809 O O   . LEU B 1 567 ? -16.25476 16.94492  -6.94170  1.000 79.45835  ? 566 LEU B O   1 
ATOM   8810 C CB  . LEU B 1 567 ? -13.52042 17.22096  -6.91897  1.000 65.60450  ? 566 LEU B CB  1 
ATOM   8811 C CG  . LEU B 1 567 ? -12.11151 17.02409  -6.35258  1.000 56.68416  ? 566 LEU B CG  1 
ATOM   8812 C CD1 . LEU B 1 567 ? -11.34021 18.33401  -6.31832  1.000 55.86496  ? 566 LEU B CD1 1 
ATOM   8813 C CD2 . LEU B 1 567 ? -12.15879 16.42386  -4.97197  1.000 56.81960  ? 566 LEU B CD2 1 
ATOM   8814 N N   . SER B 1 568 ? -16.30090 15.67590  -8.81088  1.000 80.24682  ? 567 SER B N   1 
ATOM   8815 C CA  . SER B 1 568 ? -17.75184 15.67511  -8.97568  1.000 81.53529  ? 567 SER B CA  1 
ATOM   8816 C C   . SER B 1 568 ? -18.18762 14.41448  -9.71998  1.000 88.02439  ? 567 SER B C   1 
ATOM   8817 O O   . SER B 1 568 ? -19.38325 14.09099  -9.75141  1.000 84.65518  ? 567 SER B O   1 
ATOM   8818 C CB  . SER B 1 568 ? -18.21484 16.92349  -9.73852  1.000 80.90778  ? 567 SER B CB  1 
ATOM   8819 O OG  . SER B 1 568 ? -17.43705 18.05883  -9.39751  1.000 67.25420  ? 567 SER B OG  1 
ATOM   8820 N N   . ASN B 1 569 ? -17.20336 13.70793  -10.30027 1.000 87.32209  ? 568 ASN B N   1 
ATOM   8821 C CA  . ASN B 1 569 ? -17.35600 12.54983  -11.19656 1.000 75.35246  ? 568 ASN B CA  1 
ATOM   8822 C C   . ASN B 1 569 ? -18.60553 11.70721  -10.96866 1.000 79.50275  ? 568 ASN B C   1 
ATOM   8823 O O   . ASN B 1 569 ? -19.53519 11.73720  -11.78178 1.000 78.11819  ? 568 ASN B O   1 
ATOM   8824 C CB  . ASN B 1 569 ? -16.12229 11.65172  -11.08591 1.000 67.89327  ? 568 ASN B CB  1 
ATOM   8825 N N   . ARG B 1 572 ? -18.28669 10.20638  -13.60561 1.000 79.82153  ? 571 ARG B N   1 
ATOM   8826 C CA  . ARG B 1 572 ? -18.51786 10.91164  -14.86296 1.000 79.43589  ? 571 ARG B CA  1 
ATOM   8827 C C   . ARG B 1 572 ? -17.72257 12.22452  -14.93561 1.000 88.01488  ? 571 ARG B C   1 
ATOM   8828 O O   . ARG B 1 572 ? -18.30302 13.30918  -15.07637 1.000 85.75510  ? 571 ARG B O   1 
ATOM   8829 C CB  . ARG B 1 572 ? -20.01011 11.18723  -15.04633 1.000 80.04566  ? 571 ARG B CB  1 
ATOM   8830 N N   . MET B 1 573 ? -16.39245 12.10142  -14.83919 1.000 86.57812  ? 572 MET B N   1 
ATOM   8831 C CA  . MET B 1 573 ? -15.49870 13.25719  -14.91034 1.000 83.29949  ? 572 MET B CA  1 
ATOM   8832 C C   . MET B 1 573 ? -15.86680 14.17991  -16.07772 1.000 85.57097  ? 572 MET B C   1 
ATOM   8833 O O   . MET B 1 573 ? -16.03316 15.39024  -15.89326 1.000 86.22302  ? 572 MET B O   1 
ATOM   8834 C CB  . MET B 1 573 ? -14.04661 12.76409  -15.01310 1.000 83.58161  ? 572 MET B CB  1 
ATOM   8835 C CG  . MET B 1 573 ? -12.96506 13.79344  -14.67296 1.000 80.92028  ? 572 MET B CG  1 
ATOM   8836 S SD  . MET B 1 573 ? -11.28331 13.10464  -14.66814 1.000 86.14074  ? 572 MET B SD  1 
ATOM   8837 C CE  . MET B 1 573 ? -10.53094 13.97501  -16.04916 1.000 70.98377  ? 572 MET B CE  1 
ATOM   8838 N N   . VAL B 1 574 ? -16.01569 13.62040  -17.28460 1.000 89.16116  ? 573 VAL B N   1 
ATOM   8839 C CA  . VAL B 1 574 ? -16.53493 14.35004  -18.45373 1.000 80.25909  ? 573 VAL B CA  1 
ATOM   8840 C C   . VAL B 1 574 ? -17.77666 13.63918  -19.00427 1.000 81.51210  ? 573 VAL B C   1 
ATOM   8841 O O   . VAL B 1 574 ? -18.49797 14.16263  -19.86090 1.000 89.79309  ? 573 VAL B O   1 
ATOM   8842 C CB  . VAL B 1 574 ? -15.46728 14.49519  -19.55594 1.000 68.16373  ? 573 VAL B CB  1 
ATOM   8843 C CG1 . VAL B 1 574 ? -15.82065 15.64301  -20.51191 1.000 70.55135  ? 573 VAL B CG1 1 
ATOM   8844 C CG2 . VAL B 1 574 ? -14.10575 14.69798  -18.94438 1.000 65.76158  ? 573 VAL B CG2 1 
ATOM   8845 N N   . ASP B 1 578 ? -19.80788 18.27876  -22.95589 1.000 63.82860  ? 577 ASP B N   1 
ATOM   8846 C CA  . ASP B 1 578 ? -18.51979 17.59664  -22.89986 1.000 78.48352  ? 577 ASP B CA  1 
ATOM   8847 C C   . ASP B 1 578 ? -17.48806 18.21941  -23.85917 1.000 83.70571  ? 577 ASP B C   1 
ATOM   8848 O O   . ASP B 1 578 ? -16.38549 17.68591  -24.01581 1.000 90.29815  ? 577 ASP B O   1 
ATOM   8849 C CB  . ASP B 1 578 ? -18.69242 16.09920  -23.20911 1.000 78.87854  ? 577 ASP B CB  1 
ATOM   8850 N N   . SER B 1 579 ? -17.84258 19.33963  -24.49500 1.000 76.50593  ? 578 SER B N   1 
ATOM   8851 C CA  . SER B 1 579 ? -16.92522 20.07864  -25.35641 1.000 75.85530  ? 578 SER B CA  1 
ATOM   8852 C C   . SER B 1 579 ? -16.01041 20.97688  -24.52230 1.000 74.84611  ? 578 SER B C   1 
ATOM   8853 O O   . SER B 1 579 ? -16.19129 21.13816  -23.31491 1.000 74.70534  ? 578 SER B O   1 
ATOM   8854 C CB  . SER B 1 579 ? -17.69870 20.92340  -26.36978 1.000 76.59457  ? 578 SER B CB  1 
ATOM   8855 N N   . TYR B 1 580 ? -15.02721 21.59403  -25.18611 1.000 72.83771  ? 579 TYR B N   1 
ATOM   8856 C CA  . TYR B 1 580 ? -14.10395 22.47443  -24.46934 1.000 74.40747  ? 579 TYR B CA  1 
ATOM   8857 C C   . TYR B 1 580 ? -14.83759 23.62559  -23.79349 1.000 72.32874  ? 579 TYR B C   1 
ATOM   8858 O O   . TYR B 1 580 ? -14.49189 24.01501  -22.67417 1.000 72.92886  ? 579 TYR B O   1 
ATOM   8859 C CB  . TYR B 1 580 ? -13.02961 23.02178  -25.41081 1.000 76.10275  ? 579 TYR B CB  1 
ATOM   8860 C CG  . TYR B 1 580 ? -11.80929 22.14178  -25.47455 1.000 72.73628  ? 579 TYR B CG  1 
ATOM   8861 C CD1 . TYR B 1 580 ? -11.36187 21.46748  -24.34422 1.000 65.47039  ? 579 TYR B CD1 1 
ATOM   8862 C CD2 . TYR B 1 580 ? -11.11614 21.96250  -26.67097 1.000 69.80682  ? 579 TYR B CD2 1 
ATOM   8863 C CE1 . TYR B 1 580 ? -10.24997 20.64292  -24.40069 1.000 67.88886  ? 579 TYR B CE1 1 
ATOM   8864 C CE2 . TYR B 1 580 ? -10.00345 21.13853  -26.73731 1.000 62.36493  ? 579 TYR B CE2 1 
ATOM   8865 C CZ  . TYR B 1 580 ? -9.57735  20.48253  -25.59975 1.000 65.10952  ? 579 TYR B CZ  1 
ATOM   8866 O OH  . TYR B 1 580 ? -8.47610  19.66399  -25.65914 1.000 65.63780  ? 579 TYR B OH  1 
ATOM   8867 N N   . SER B 1 581 ? -15.84532 24.18813  -24.46012 1.000 68.60941  ? 580 SER B N   1 
ATOM   8868 C CA  . SER B 1 581 ? -16.62647 25.25745  -23.85151 1.000 65.14577  ? 580 SER B CA  1 
ATOM   8869 C C   . SER B 1 581 ? -17.20200 24.82957  -22.50503 1.000 77.25278  ? 580 SER B C   1 
ATOM   8870 O O   . SER B 1 581 ? -17.23272 25.62398  -21.55698 1.000 80.61133  ? 580 SER B O   1 
ATOM   8871 C CB  . SER B 1 581 ? -17.74373 25.68381  -24.79977 1.000 67.90572  ? 580 SER B CB  1 
ATOM   8872 O OG  . SER B 1 581 ? -18.26863 24.56488  -25.49559 1.000 76.32488  ? 580 SER B OG  1 
ATOM   8873 N N   . THR B 1 582 ? -17.65100 23.57090  -22.40012 1.000 78.38426  ? 581 THR B N   1 
ATOM   8874 C CA  . THR B 1 582 ? -18.24457 23.07527  -21.15841 1.000 73.11260  ? 581 THR B CA  1 
ATOM   8875 C C   . THR B 1 582 ? -17.24706 23.09758  -20.01254 1.000 74.27165  ? 581 THR B C   1 
ATOM   8876 O O   . THR B 1 582 ? -17.60206 23.43067  -18.87526 1.000 75.15820  ? 581 THR B O   1 
ATOM   8877 C CB  . THR B 1 582 ? -18.74965 21.64668  -21.34279 1.000 74.57332  ? 581 THR B CB  1 
ATOM   8878 O OG1 . THR B 1 582 ? -19.71462 21.60890  -22.39370 1.000 72.07916  ? 581 THR B OG1 1 
ATOM   8879 C CG2 . THR B 1 582 ? -19.38005 21.12944  -20.04352 1.000 81.79809  ? 581 THR B CG2 1 
ATOM   8880 N N   . LEU B 1 583 ? -16.00192 22.71581  -20.28856 1.000 70.80949  ? 582 LEU B N   1 
ATOM   8881 C CA  . LEU B 1 583 ? -15.00626 22.52915  -19.24671 1.000 74.16886  ? 582 LEU B CA  1 
ATOM   8882 C C   . LEU B 1 583 ? -14.16822 23.77573  -18.99199 1.000 74.35147  ? 582 LEU B C   1 
ATOM   8883 O O   . LEU B 1 583 ? -13.53601 23.87422  -17.93194 1.000 72.15415  ? 582 LEU B O   1 
ATOM   8884 C CB  . LEU B 1 583 ? -14.10181 21.34467  -19.61123 1.000 69.13601  ? 582 LEU B CB  1 
ATOM   8885 C CG  . LEU B 1 583 ? -14.83176 19.99922  -19.71018 1.000 64.10837  ? 582 LEU B CG  1 
ATOM   8886 C CD1 . LEU B 1 583 ? -14.97491 19.55286  -21.12862 1.000 70.99004  ? 582 LEU B CD1 1 
ATOM   8887 C CD2 . LEU B 1 583 ? -14.10304 18.93833  -18.94722 1.000 63.10159  ? 582 LEU B CD2 1 
ATOM   8888 N N   . VAL B 1 584 ? -14.18343 24.73579  -19.92071 1.000 75.40994  ? 583 VAL B N   1 
ATOM   8889 C CA  . VAL B 1 584 ? -13.34047 25.92766  -19.83919 1.000 73.92697  ? 583 VAL B CA  1 
ATOM   8890 C C   . VAL B 1 584 ? -13.74991 26.80049  -18.65484 1.000 68.11260  ? 583 VAL B C   1 
ATOM   8891 O O   . VAL B 1 584 ? -14.93912 26.92651  -18.32763 1.000 72.74968  ? 583 VAL B O   1 
ATOM   8892 C CB  . VAL B 1 584 ? -13.41513 26.68329  -21.18172 1.000 67.60850  ? 583 VAL B CB  1 
ATOM   8893 C CG1 . VAL B 1 584 ? -13.18357 28.16001  -21.00683 1.000 68.68143  ? 583 VAL B CG1 1 
ATOM   8894 C CG2 . VAL B 1 584 ? -12.39665 26.11185  -22.17030 1.000 64.05818  ? 583 VAL B CG2 1 
ATOM   8895 N N   . ASP B 1 585 ? -12.75934 27.39603  -17.99034 1.000 65.80551  ? 584 ASP B N   1 
ATOM   8896 C CA  . ASP B 1 585 ? -13.03274 28.27944  -16.86158 1.000 75.50864  ? 584 ASP B CA  1 
ATOM   8897 C C   . ASP B 1 585 ? -13.37207 29.68868  -17.33643 1.000 81.69383  ? 584 ASP B C   1 
ATOM   8898 O O   . ASP B 1 585 ? -12.73450 30.23546  -18.24785 1.000 73.57259  ? 584 ASP B O   1 
ATOM   8899 C CB  . ASP B 1 585 ? -11.84028 28.33332  -15.89791 1.000 72.96529  ? 584 ASP B CB  1 
ATOM   8900 C CG  . ASP B 1 585 ? -12.23277 28.81360  -14.49264 1.000 72.67650  ? 584 ASP B CG  1 
ATOM   8901 O OD1 . ASP B 1 585 ? -12.63359 29.98611  -14.34928 1.000 74.79421  ? 584 ASP B OD1 1 
ATOM   8902 O OD2 . ASP B 1 585 ? -12.14577 28.01686  -13.53044 1.000 66.98431  ? 584 ASP B OD2 1 
ATOM   8903 N N   . ASN B 1 586 ? -14.38736 30.27750  -16.69641 1.000 86.73695  ? 585 ASN B N   1 
ATOM   8904 C CA  . ASN B 1 586 ? -14.76426 31.65270  -17.00433 1.000 88.57295  ? 585 ASN B CA  1 
ATOM   8905 C C   . ASN B 1 586 ? -13.67607 32.63214  -16.57696 1.000 87.27479  ? 585 ASN B C   1 
ATOM   8906 O O   . ASN B 1 586 ? -13.40467 33.61136  -17.28522 1.000 87.07444  ? 585 ASN B O   1 
ATOM   8907 C CB  . ASN B 1 586 ? -16.09736 31.99411  -16.33002 1.000 83.77423  ? 585 ASN B CB  1 
ATOM   8908 N N   . GLU B 1 587 ? -13.02121 32.36903  -15.43994 1.000 82.00807  ? 586 GLU B N   1 
ATOM   8909 C CA  . GLU B 1 587 ? -12.11567 33.33041  -14.81820 1.000 77.62223  ? 586 GLU B CA  1 
ATOM   8910 C C   . GLU B 1 587 ? -10.63573 33.02098  -15.03562 1.000 75.98621  ? 586 GLU B C   1 
ATOM   8911 O O   . GLU B 1 587 ? -9.89897  33.90145  -15.48449 1.000 81.33103  ? 586 GLU B O   1 
ATOM   8912 C CB  . GLU B 1 587 ? -12.41343 33.44399  -13.31597 1.000 83.15830  ? 586 GLU B CB  1 
ATOM   8913 C CG  . GLU B 1 587 ? -13.88547 33.67204  -12.99067 1.000 87.32261  ? 586 GLU B CG  1 
ATOM   8914 C CD  . GLU B 1 587 ? -14.49968 34.81224  -13.79140 1.000 96.78845  ? 586 GLU B CD  1 
ATOM   8915 O OE1 . GLU B 1 587 ? -14.22521 35.98957  -13.46623 1.000 100.75281 ? 586 GLU B OE1 1 
ATOM   8916 O OE2 . GLU B 1 587 ? -15.24368 34.53007  -14.75925 1.000 93.08367  ? 586 GLU B OE2 1 
ATOM   8917 N N   . HIS B 1 588 ? -10.16521 31.81048  -14.72424 1.000 70.61468  ? 587 HIS B N   1 
ATOM   8918 C CA  . HIS B 1 588 ? -8.72379  31.55927  -14.76440 1.000 61.80801  ? 587 HIS B CA  1 
ATOM   8919 C C   . HIS B 1 588 ? -8.21182  31.65954  -16.19251 1.000 65.97598  ? 587 HIS B C   1 
ATOM   8920 O O   . HIS B 1 588 ? -8.68041  30.93732  -17.08063 1.000 72.57783  ? 587 HIS B O   1 
ATOM   8921 C CB  . HIS B 1 588 ? -8.37489  30.19255  -14.18264 1.000 60.04923  ? 587 HIS B CB  1 
ATOM   8922 C CG  . HIS B 1 588 ? -6.91157  30.01342  -13.92069 1.000 58.62474  ? 587 HIS B CG  1 
ATOM   8923 N ND1 . HIS B 1 588 ? -6.36270  28.81217  -13.53312 1.000 61.02269  ? 587 HIS B ND1 1 
ATOM   8924 C CD2 . HIS B 1 588 ? -5.88095  30.88899  -13.98819 1.000 62.66562  ? 587 HIS B CD2 1 
ATOM   8925 C CE1 . HIS B 1 588 ? -5.05926  28.95448  -13.36889 1.000 57.46919  ? 587 HIS B CE1 1 
ATOM   8926 N NE2 . HIS B 1 588 ? -4.74075  30.20620  -13.63811 1.000 58.16912  ? 587 HIS B NE2 1 
ATOM   8927 N N   . ALA B 1 589 ? -7.25795  32.56028  -16.41678 1.000 59.42334  ? 588 ALA B N   1 
ATOM   8928 C CA  . ALA B 1 589 ? -6.63483  32.73379  -17.72168 1.000 57.07332  ? 588 ALA B CA  1 
ATOM   8929 C C   . ALA B 1 589 ? -5.15318  32.45181  -17.57139 1.000 56.84615  ? 588 ALA B C   1 
ATOM   8930 O O   . ALA B 1 589 ? -4.48540  33.05725  -16.73065 1.000 64.11801  ? 588 ALA B O   1 
ATOM   8931 C CB  . ALA B 1 589 ? -6.86388  34.13843  -18.28153 1.000 54.03311  ? 588 ALA B CB  1 
ATOM   8932 N N   . LEU B 1 590 ? -4.64902  31.52309  -18.36202 1.000 58.45856  ? 589 LEU B N   1 
ATOM   8933 C CA  . LEU B 1 590 ? -3.24017  31.19221  -18.31171 1.000 56.02672  ? 589 LEU B CA  1 
ATOM   8934 C C   . LEU B 1 590 ? -2.48275  32.00714  -19.34913 1.000 56.13249  ? 589 LEU B C   1 
ATOM   8935 O O   . LEU B 1 590 ? -3.01234  32.37158  -20.40195 1.000 56.46356  ? 589 LEU B O   1 
ATOM   8936 C CB  . LEU B 1 590 ? -3.02221  29.69281  -18.53985 1.000 54.64012  ? 589 LEU B CB  1 
ATOM   8937 C CG  . LEU B 1 590 ? -3.46314  28.78164  -17.38516 1.000 57.08655  ? 589 LEU B CG  1 
ATOM   8938 C CD1 . LEU B 1 590 ? -4.25607  27.59650  -17.90649 1.000 53.54022  ? 589 LEU B CD1 1 
ATOM   8939 C CD2 . LEU B 1 590 ? -2.26705  28.31396  -16.54150 1.000 52.66859  ? 589 LEU B CD2 1 
ATOM   8940 N N   . VAL B 1 591 ? -1.23729  32.29439  -19.03664 1.000 56.43510  ? 590 VAL B N   1 
ATOM   8941 C CA  . VAL B 1 591 ? -0.37696  33.06960  -19.91422 1.000 48.47173  ? 590 VAL B CA  1 
ATOM   8942 C C   . VAL B 1 591 ? 0.41125   32.12068  -20.80164 1.000 49.97577  ? 590 VAL B C   1 
ATOM   8943 O O   . VAL B 1 591 ? 1.05307   31.18451  -20.31028 1.000 54.41388  ? 590 VAL B O   1 
ATOM   8944 C CB  . VAL B 1 591 ? 0.55595   33.96677  -19.09214 1.000 47.63322  ? 590 VAL B CB  1 
ATOM   8945 C CG1 . VAL B 1 591 ? 1.80739   34.30394  -19.87822 1.000 47.02229  ? 590 VAL B CG1 1 
ATOM   8946 C CG2 . VAL B 1 591 ? -0.18747  35.21254  -18.67489 1.000 38.26205  ? 590 VAL B CG2 1 
ATOM   8947 N N   . ASN B 1 592 ? 0.36196   32.36265  -22.10515 1.000 51.77517  ? 591 ASN B N   1 
ATOM   8948 C CA  . ASN B 1 592 ? 1.02758   31.53004  -23.09984 1.000 49.00983  ? 591 ASN B CA  1 
ATOM   8949 C C   . ASN B 1 592 ? 2.53179   31.66375  -22.97561 1.000 48.53974  ? 591 ASN B C   1 
ATOM   8950 O O   . ASN B 1 592 ? 3.08850   32.67982  -23.40544 1.000 52.32403  ? 591 ASN B O   1 
ATOM   8951 C CB  . ASN B 1 592 ? 0.58701   31.92332  -24.50293 1.000 50.48079  ? 591 ASN B CB  1 
ATOM   8952 C CG  . ASN B 1 592 ? 0.81696   30.82350  -25.51597 1.000 50.73722  ? 591 ASN B CG  1 
ATOM   8953 O OD1 . ASN B 1 592 ? 1.62770   29.91733  -25.29954 1.000 52.69475  ? 591 ASN B OD1 1 
ATOM   8954 N ND2 . ASN B 1 592 ? 0.10509   30.89720  -26.63198 1.000 43.64204  ? 591 ASN B ND2 1 
ATOM   8955 N N   . PRO B 1 593 ? 3.23341   30.67134  -22.43896 1.000 49.30273  ? 592 PRO B N   1 
ATOM   8956 C CA  . PRO B 1 593 ? 4.68915   30.81375  -22.27840 1.000 53.99439  ? 592 PRO B CA  1 
ATOM   8957 C C   . PRO B 1 593 ? 5.43451   31.06478  -23.58402 1.000 61.09313  ? 592 PRO B C   1 
ATOM   8958 O O   . PRO B 1 593 ? 6.64359   31.31459  -23.52559 1.000 67.39436  ? 592 PRO B O   1 
ATOM   8959 C CB  . PRO B 1 593 ? 5.11379   29.48176  -21.64517 1.000 54.33715  ? 592 PRO B CB  1 
ATOM   8960 C CG  . PRO B 1 593 ? 3.99890   28.52759  -21.98505 1.000 57.63057  ? 592 PRO B CG  1 
ATOM   8961 C CD  . PRO B 1 593 ? 2.74188   29.32357  -22.11448 1.000 46.84099  ? 592 PRO B CD  1 
ATOM   8962 N N   . ILE B 1 594 ? 4.77761   31.00294  -24.74652 1.000 54.84801  ? 593 ILE B N   1 
ATOM   8963 C CA  . ILE B 1 594 ? 5.46085   31.24098  -26.01161 1.000 59.47692  ? 593 ILE B CA  1 
ATOM   8964 C C   . ILE B 1 594 ? 5.03995   32.54383  -26.68104 1.000 62.67726  ? 593 ILE B C   1 
ATOM   8965 O O   . ILE B 1 594 ? 5.78556   33.04003  -27.54377 1.000 61.33281  ? 593 ILE B O   1 
ATOM   8966 C CB  . ILE B 1 594 ? 5.28570   30.06418  -26.99805 1.000 56.07216  ? 593 ILE B CB  1 
ATOM   8967 C CG1 . ILE B 1 594 ? 3.81894   29.90581  -27.40364 1.000 50.09843  ? 593 ILE B CG1 1 
ATOM   8968 C CG2 . ILE B 1 594 ? 5.87629   28.78915  -26.43195 1.000 54.18879  ? 593 ILE B CG2 1 
ATOM   8969 C CD1 . ILE B 1 594 ? 3.64287   29.28433  -28.74342 1.000 41.33710  ? 593 ILE B CD1 1 
ATOM   8970 N N   . ALA B 1 595 ? 3.88217   33.11018  -26.32356 1.000 54.88267  ? 594 ALA B N   1 
ATOM   8971 C CA  . ALA B 1 595 ? 3.42105   34.32921  -26.98093 1.000 54.44996  ? 594 ALA B CA  1 
ATOM   8972 C C   . ALA B 1 595 ? 4.48019   35.42193  -26.92660 1.000 66.66268  ? 594 ALA B C   1 
ATOM   8973 O O   . ALA B 1 595 ? 4.70240   36.13231  -27.91605 1.000 71.37902  ? 594 ALA B O   1 
ATOM   8974 C CB  . ALA B 1 595 ? 2.11377   34.81538  -26.34904 1.000 52.14407  ? 594 ALA B CB  1 
ATOM   8975 N N   . GLY B 1 596 ? 5.17401   35.54455  -25.79176 1.000 66.68780  ? 595 GLY B N   1 
ATOM   8976 C CA  . GLY B 1 596 ? 6.24206   36.52080  -25.65734 1.000 59.14573  ? 595 GLY B CA  1 
ATOM   8977 C C   . GLY B 1 596 ? 7.38653   36.33234  -26.63102 1.000 68.23001  ? 595 GLY B C   1 
ATOM   8978 O O   . GLY B 1 596 ? 8.27359   37.19223  -26.68855 1.000 74.61834  ? 595 GLY B O   1 
ATOM   8979 N N   . HIS B 1 597 ? 7.37973   35.24863  -27.41037 1.000 66.29419  ? 596 HIS B N   1 
ATOM   8980 C CA  . HIS B 1 597 ? 8.44676   34.94669  -28.35459 1.000 65.89228  ? 596 HIS B CA  1 
ATOM   8981 C C   . HIS B 1 597 ? 7.99987   35.06955  -29.80962 1.000 66.55659  ? 596 HIS B C   1 
ATOM   8982 O O   . HIS B 1 597 ? 8.60296   34.44850  -30.69498 1.000 67.21514  ? 596 HIS B O   1 
ATOM   8983 C CB  . HIS B 1 597 ? 8.99104   33.53888  -28.10578 1.000 65.30690  ? 596 HIS B CB  1 
ATOM   8984 C CG  . HIS B 1 597 ? 9.59727   33.34173  -26.75231 1.000 64.47049  ? 596 HIS B CG  1 
ATOM   8985 N ND1 . HIS B 1 597 ? 8.92859   33.63556  -25.58513 1.000 68.48977  ? 596 HIS B ND1 1 
ATOM   8986 C CD2 . HIS B 1 597 ? 10.81013  32.86200  -26.38196 1.000 60.89010  ? 596 HIS B CD2 1 
ATOM   8987 C CE1 . HIS B 1 597 ? 9.70647   33.34893  -24.55433 1.000 72.45931  ? 596 HIS B CE1 1 
ATOM   8988 N NE2 . HIS B 1 597 ? 10.85337  32.87814  -25.01223 1.000 60.19401  ? 596 HIS B NE2 1 
ATOM   8989 N N   . ARG B 1 598 ? 6.94190   35.83107  -30.08446 1.000 64.07463  ? 597 ARG B N   1 
ATOM   8990 C CA  . ARG B 1 598 ? 6.54295   36.00300  -31.47724 1.000 68.41648  ? 597 ARG B CA  1 
ATOM   8991 C C   . ARG B 1 598 ? 7.67388   36.62304  -32.30384 1.000 75.72258  ? 597 ARG B C   1 
ATOM   8992 O O   . ARG B 1 598 ? 7.75193   36.39789  -33.52262 1.000 75.60066  ? 597 ARG B O   1 
ATOM   8993 C CB  . ARG B 1 598 ? 5.23523   36.82207  -31.52162 1.000 65.94604  ? 597 ARG B CB  1 
ATOM   8994 C CG  . ARG B 1 598 ? 4.57000   36.95998  -32.90424 1.000 73.36526  ? 597 ARG B CG  1 
ATOM   8995 C CD  . ARG B 1 598 ? 3.91213   35.66834  -33.40445 1.000 66.12803  ? 597 ARG B CD  1 
ATOM   8996 N NE  . ARG B 1 598 ? 4.78828   34.90106  -34.29288 1.000 74.92013  ? 597 ARG B NE  1 
ATOM   8997 C CZ  . ARG B 1 598 ? 4.37793   33.96212  -35.14118 1.000 75.26313  ? 597 ARG B CZ  1 
ATOM   8998 N NH1 . ARG B 1 598 ? 3.09648   33.64389  -35.25443 1.000 78.57510  ? 597 ARG B NH1 1 
ATOM   8999 N NH2 . ARG B 1 598 ? 5.27551   33.32493  -35.89468 1.000 66.97265  ? 597 ARG B NH2 1 
ATOM   9000 N N   . GLY B 1 599 ? 8.58272   37.34064  -31.64318 1.000 70.15806  ? 598 GLY B N   1 
ATOM   9001 C CA  . GLY B 1 599 ? 9.72937   38.00480  -32.24604 1.000 68.28196  ? 598 GLY B CA  1 
ATOM   9002 C C   . GLY B 1 599 ? 10.61780  37.20397  -33.18563 1.000 80.51393  ? 598 GLY B C   1 
ATOM   9003 O O   . GLY B 1 599 ? 10.58719  37.44946  -34.39999 1.000 92.91463  ? 598 GLY B O   1 
ATOM   9004 N N   . ALA B 1 600 ? 11.42127  36.25478  -32.65446 1.000 70.18630  ? 599 ALA B N   1 
ATOM   9005 C CA  . ALA B 1 600 ? 12.46346  35.58928  -33.44840 1.000 73.09710  ? 599 ALA B CA  1 
ATOM   9006 C C   . ALA B 1 600 ? 11.93630  34.51125  -34.41407 1.000 78.59773  ? 599 ALA B C   1 
ATOM   9007 O O   . ALA B 1 600 ? 12.75037  33.76795  -34.97030 1.000 79.13066  ? 599 ALA B O   1 
ATOM   9008 C CB  . ALA B 1 600 ? 13.53412  34.98680  -32.53425 1.000 69.34875  ? 599 ALA B CB  1 
ATOM   9009 N N   . VAL B 1 601 ? 10.62498  34.42320  -34.64822 1.000 74.60072  ? 600 VAL B N   1 
ATOM   9010 C CA  . VAL B 1 601 ? 10.07181  33.52113  -35.66802 1.000 71.59334  ? 600 VAL B CA  1 
ATOM   9011 C C   . VAL B 1 601 ? 10.61969  33.80264  -37.07080 1.000 80.37128  ? 600 VAL B C   1 
ATOM   9012 O O   . VAL B 1 601 ? 9.91194   33.63347  -38.06744 1.000 79.74567  ? 600 VAL B O   1 
ATOM   9013 C CB  . VAL B 1 601 ? 8.53788   33.60186  -35.70064 1.000 75.01415  ? 600 VAL B CB  1 
HETATM 9014 C C1  . MLI C 2 .   ? -26.46658 -13.81088 12.73415  1.000 51.44805  ? 701 MLI A C1  1 
HETATM 9015 C C2  . MLI C 2 .   ? -26.58271 -13.02647 11.43063  1.000 54.38526  ? 701 MLI A C2  1 
HETATM 9016 C C3  . MLI C 2 .   ? -26.61881 -15.32095 12.56943  1.000 62.11909  ? 701 MLI A C3  1 
HETATM 9017 O O6  . MLI C 2 .   ? -25.75631 -13.27073 10.52473  1.000 45.47342  ? 701 MLI A O6  1 
HETATM 9018 O O7  . MLI C 2 .   ? -27.48767 -12.16389 11.34211  1.000 61.71278  ? 701 MLI A O7  1 
HETATM 9019 O O8  . MLI C 2 .   ? -25.60299 -16.03747 12.74666  1.000 62.23749  ? 701 MLI A O8  1 
HETATM 9020 O O9  . MLI C 2 .   ? -27.75785 -15.77329 12.29122  1.000 65.12603  ? 701 MLI A O9  1 
HETATM 9021 C C1  . MLI D 2 .   ? -7.31187  2.92784   -24.12409 1.000 51.47435  ? 701 MLI B C1  1 
HETATM 9022 C C2  . MLI D 2 .   ? -5.81099  2.66756   -24.11588 1.000 53.69549  ? 701 MLI B C2  1 
HETATM 9023 C C3  . MLI D 2 .   ? -7.83891  3.30727   -22.73779 1.000 58.30678  ? 701 MLI B C3  1 
HETATM 9024 O O6  . MLI D 2 .   ? -5.08047  3.50066   -23.56252 1.000 57.08607  ? 701 MLI B O6  1 
HETATM 9025 O O7  . MLI D 2 .   ? -5.38965  1.63699   -24.66455 1.000 56.04678  ? 701 MLI B O7  1 
HETATM 9026 O O8  . MLI D 2 .   ? -7.56672  2.55240   -21.76357 1.000 42.09860  ? 701 MLI B O8  1 
HETATM 9027 O O9  . MLI D 2 .   ? -8.52681  4.35624   -22.64517 1.000 63.08346  ? 701 MLI B O9  1 
# 
