data_9NGL
# 
_entry.id   9NGL 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NGL         pdb_00009ngl 10.2210/pdb9ngl/pdb 
WWPDB D_1000293318 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NGL 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 geiger@chemistry.msu.edu James Geiger H 'principal investigator/group leader' 0000-0002-9443-4488 
3 draths@chemistry.msu.edu Karen Draths ? 'principal investigator/group leader' 0000-0001-7852-1090 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Silva, K.'    1 ? 
'Geiger, J.H.' 2 ? 
'Draths, K.'   3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'cis-CaaD E114Q' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Silva, K.'    1 ? 
primary 'Geiger, J.H.' 2 ? 
primary 'Draths, K.'   3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cis-3-chloroacrylic acid dehalogenase' 18566.598 3   ? E114Q ? ? 
2 non-polymer syn 'PHOSPHATE ION'                         94.971    3   ? ?     ? ? 
3 water       nat water                                   18.015    387 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVQYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVQYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PHOSPHATE ION' PO4 
3 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   VAL n 
1 3   TYR n 
1 4   MET n 
1 5   VAL n 
1 6   TYR n 
1 7   VAL n 
1 8   SER n 
1 9   GLN n 
1 10  ASP n 
1 11  ARG n 
1 12  LEU n 
1 13  THR n 
1 14  PRO n 
1 15  SER n 
1 16  ALA n 
1 17  LYS n 
1 18  HIS n 
1 19  ALA n 
1 20  VAL n 
1 21  ALA n 
1 22  LYS n 
1 23  ALA n 
1 24  ILE n 
1 25  THR n 
1 26  ASP n 
1 27  ALA n 
1 28  HIS n 
1 29  ARG n 
1 30  GLY n 
1 31  LEU n 
1 32  THR n 
1 33  GLY n 
1 34  THR n 
1 35  GLN n 
1 36  HIS n 
1 37  PHE n 
1 38  LEU n 
1 39  ALA n 
1 40  GLN n 
1 41  VAL n 
1 42  ASN n 
1 43  PHE n 
1 44  GLN n 
1 45  GLU n 
1 46  GLN n 
1 47  PRO n 
1 48  ALA n 
1 49  GLY n 
1 50  ASN n 
1 51  VAL n 
1 52  PHE n 
1 53  LEU n 
1 54  GLY n 
1 55  GLY n 
1 56  VAL n 
1 57  GLN n 
1 58  GLN n 
1 59  GLY n 
1 60  GLY n 
1 61  ASP n 
1 62  THR n 
1 63  ILE n 
1 64  PHE n 
1 65  VAL n 
1 66  HIS n 
1 67  GLY n 
1 68  LEU n 
1 69  HIS n 
1 70  ARG n 
1 71  GLU n 
1 72  GLY n 
1 73  ARG n 
1 74  SER n 
1 75  ALA n 
1 76  ASP n 
1 77  LEU n 
1 78  LYS n 
1 79  GLY n 
1 80  GLN n 
1 81  LEU n 
1 82  ALA n 
1 83  GLN n 
1 84  ARG n 
1 85  ILE n 
1 86  VAL n 
1 87  ASP n 
1 88  ASP n 
1 89  VAL n 
1 90  SER n 
1 91  VAL n 
1 92  ALA n 
1 93  ALA n 
1 94  GLU n 
1 95  ILE n 
1 96  ASP n 
1 97  ARG n 
1 98  LYS n 
1 99  HIS n 
1 100 ILE n 
1 101 TRP n 
1 102 VAL n 
1 103 TYR n 
1 104 PHE n 
1 105 GLY n 
1 106 GLU n 
1 107 MET n 
1 108 PRO n 
1 109 ALA n 
1 110 GLN n 
1 111 GLN n 
1 112 MET n 
1 113 VAL n 
1 114 GLN n 
1 115 TYR n 
1 116 GLY n 
1 117 ARG n 
1 118 PHE n 
1 119 LEU n 
1 120 PRO n 
1 121 GLN n 
1 122 PRO n 
1 123 GLY n 
1 124 HIS n 
1 125 GLU n 
1 126 GLY n 
1 127 GLU n 
1 128 TRP n 
1 129 PHE n 
1 130 ASP n 
1 131 ASN n 
1 132 LEU n 
1 133 SER n 
1 134 SER n 
1 135 ASP n 
1 136 GLU n 
1 137 ARG n 
1 138 ALA n 
1 139 PHE n 
1 140 MET n 
1 141 GLU n 
1 142 THR n 
1 143 ASN n 
1 144 VAL n 
1 145 ASP n 
1 146 VAL n 
1 147 SER n 
1 148 ARG n 
1 149 THR n 
1 150 GLU n 
1 151 ASN n 
1 152 LEU n 
1 153 TYR n 
1 154 PHE n 
1 155 GLN n 
1 156 GLY n 
1 157 LEU n 
1 158 GLU n 
1 159 HIS n 
1 160 HIS n 
1 161 HIS n 
1 162 HIS n 
1 163 HIS n 
1 164 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   164 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 cis-caaD 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'coryneform bacterium' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1728 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PO4 non-polymer         . 'PHOSPHATE ION' ? 'O4 P -3'        94.971  
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   1   1   PRO PRO A . n 
A 1 2   VAL 2   2   2   VAL VAL A . n 
A 1 3   TYR 3   3   3   TYR TYR A . n 
A 1 4   MET 4   4   4   MET MET A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   SER 8   8   8   SER SER A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  HIS 28  28  28  HIS HIS A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  HIS 36  36  36  HIS HIS A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  GLN 40  40  40  GLN GLN A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  GLN 44  44  44  GLN GLN A . n 
A 1 45  GLU 45  45  45  GLU GLU A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ASN 50  50  50  ASN ASN A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  THR 62  62  62  THR THR A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  PHE 64  64  64  PHE PHE A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  HIS 66  66  66  HIS HIS A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  HIS 69  69  69  HIS HIS A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  GLN 80  80  80  GLN GLN A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  GLU 94  94  94  GLU GLU A . n 
A 1 95  ILE 95  95  95  ILE ILE A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  LYS 98  98  98  LYS LYS A . n 
A 1 99  HIS 99  99  99  HIS HIS A . n 
A 1 100 ILE 100 100 100 ILE ILE A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 TYR 103 103 103 TYR TYR A . n 
A 1 104 PHE 104 104 104 PHE PHE A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLN 111 111 111 GLN GLN A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 GLN 114 114 114 GLN GLN A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 PHE 118 118 118 PHE PHE A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PRO 120 120 120 PRO PRO A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 HIS 124 124 124 HIS HIS A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 ARG 137 137 137 ARG ARG A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 MET 140 140 140 MET MET A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 THR 142 142 142 THR THR A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 VAL 146 146 ?   ?   ?   A . n 
A 1 147 SER 147 147 ?   ?   ?   A . n 
A 1 148 ARG 148 148 ?   ?   ?   A . n 
A 1 149 THR 149 149 ?   ?   ?   A . n 
A 1 150 GLU 150 150 ?   ?   ?   A . n 
A 1 151 ASN 151 151 ?   ?   ?   A . n 
A 1 152 LEU 152 152 ?   ?   ?   A . n 
A 1 153 TYR 153 153 ?   ?   ?   A . n 
A 1 154 PHE 154 154 ?   ?   ?   A . n 
A 1 155 GLN 155 155 ?   ?   ?   A . n 
A 1 156 GLY 156 156 ?   ?   ?   A . n 
A 1 157 LEU 157 157 ?   ?   ?   A . n 
A 1 158 GLU 158 158 ?   ?   ?   A . n 
A 1 159 HIS 159 159 ?   ?   ?   A . n 
A 1 160 HIS 160 160 ?   ?   ?   A . n 
A 1 161 HIS 161 161 ?   ?   ?   A . n 
A 1 162 HIS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 HIS 164 164 ?   ?   ?   A . n 
B 1 1   PRO 1   1   1   PRO PRO B . n 
B 1 2   VAL 2   2   2   VAL VAL B . n 
B 1 3   TYR 3   3   3   TYR TYR B . n 
B 1 4   MET 4   4   4   MET MET B . n 
B 1 5   VAL 5   5   5   VAL VAL B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   VAL 7   7   7   VAL VAL B . n 
B 1 8   SER 8   8   8   SER SER B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  ASP 10  10  10  ASP ASP B . n 
B 1 11  ARG 11  11  11  ARG ARG B . n 
B 1 12  LEU 12  12  12  LEU LEU B . n 
B 1 13  THR 13  13  13  THR THR B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  LYS 17  17  17  LYS LYS B . n 
B 1 18  HIS 18  18  18  HIS HIS B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  ASP 26  26  26  ASP ASP B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  HIS 28  28  28  HIS HIS B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  GLY 30  30  30  GLY GLY B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  GLY 33  33  33  GLY GLY B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  HIS 36  36  36  HIS HIS B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  GLN 40  40  40  GLN GLN B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  PHE 43  43  43  PHE PHE B . n 
B 1 44  GLN 44  44  44  GLN GLN B . n 
B 1 45  GLU 45  45  45  GLU GLU B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  ALA 48  48  48  ALA ALA B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  ASN 50  50  50  ASN ASN B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  GLY 54  54  54  GLY GLY B . n 
B 1 55  GLY 55  55  55  GLY GLY B . n 
B 1 56  VAL 56  56  56  VAL VAL B . n 
B 1 57  GLN 57  57  57  GLN GLN B . n 
B 1 58  GLN 58  58  58  GLN GLN B . n 
B 1 59  GLY 59  59  59  GLY GLY B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  THR 62  62  62  THR THR B . n 
B 1 63  ILE 63  63  63  ILE ILE B . n 
B 1 64  PHE 64  64  64  PHE PHE B . n 
B 1 65  VAL 65  65  65  VAL VAL B . n 
B 1 66  HIS 66  66  66  HIS HIS B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  HIS 69  69  69  HIS HIS B . n 
B 1 70  ARG 70  70  70  ARG ARG B . n 
B 1 71  GLU 71  71  71  GLU GLU B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  ALA 75  75  75  ALA ALA B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  LEU 77  77  77  LEU LEU B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  GLN 80  80  80  GLN GLN B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ALA 82  82  82  ALA ALA B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ARG 84  84  84  ARG ARG B . n 
B 1 85  ILE 85  85  85  ILE ILE B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  ALA 93  93  93  ALA ALA B . n 
B 1 94  GLU 94  94  94  GLU GLU B . n 
B 1 95  ILE 95  95  95  ILE ILE B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  ARG 97  97  97  ARG ARG B . n 
B 1 98  LYS 98  98  98  LYS LYS B . n 
B 1 99  HIS 99  99  99  HIS HIS B . n 
B 1 100 ILE 100 100 100 ILE ILE B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 TYR 103 103 103 TYR TYR B . n 
B 1 104 PHE 104 104 104 PHE PHE B . n 
B 1 105 GLY 105 105 105 GLY GLY B . n 
B 1 106 GLU 106 106 106 GLU GLU B . n 
B 1 107 MET 107 107 107 MET MET B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 GLN 111 111 111 GLN GLN B . n 
B 1 112 MET 112 112 112 MET MET B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 GLN 114 114 114 GLN GLN B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 PHE 118 118 118 PHE PHE B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 PRO 120 120 120 PRO PRO B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLY 123 123 123 GLY GLY B . n 
B 1 124 HIS 124 124 124 HIS HIS B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 GLY 126 126 126 GLY GLY B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 PHE 129 129 129 PHE PHE B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 ASN 131 131 131 ASN ASN B . n 
B 1 132 LEU 132 132 132 LEU LEU B . n 
B 1 133 SER 133 133 133 SER SER B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 ARG 137 137 137 ARG ARG B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 MET 140 140 140 MET MET B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 THR 142 142 142 THR THR B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 VAL 144 144 144 VAL VAL B . n 
B 1 145 ASP 145 145 145 ASP ASP B . n 
B 1 146 VAL 146 146 146 VAL VAL B . n 
B 1 147 SER 147 147 ?   ?   ?   B . n 
B 1 148 ARG 148 148 ?   ?   ?   B . n 
B 1 149 THR 149 149 ?   ?   ?   B . n 
B 1 150 GLU 150 150 ?   ?   ?   B . n 
B 1 151 ASN 151 151 ?   ?   ?   B . n 
B 1 152 LEU 152 152 ?   ?   ?   B . n 
B 1 153 TYR 153 153 ?   ?   ?   B . n 
B 1 154 PHE 154 154 ?   ?   ?   B . n 
B 1 155 GLN 155 155 ?   ?   ?   B . n 
B 1 156 GLY 156 156 ?   ?   ?   B . n 
B 1 157 LEU 157 157 ?   ?   ?   B . n 
B 1 158 GLU 158 158 ?   ?   ?   B . n 
B 1 159 HIS 159 159 ?   ?   ?   B . n 
B 1 160 HIS 160 160 ?   ?   ?   B . n 
B 1 161 HIS 161 161 ?   ?   ?   B . n 
B 1 162 HIS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 HIS 164 164 ?   ?   ?   B . n 
C 1 1   PRO 1   1   1   PRO PRO C . n 
C 1 2   VAL 2   2   2   VAL VAL C . n 
C 1 3   TYR 3   3   3   TYR TYR C . n 
C 1 4   MET 4   4   4   MET MET C . n 
C 1 5   VAL 5   5   5   VAL VAL C . n 
C 1 6   TYR 6   6   6   TYR TYR C . n 
C 1 7   VAL 7   7   7   VAL VAL C . n 
C 1 8   SER 8   8   8   SER SER C . n 
C 1 9   GLN 9   9   9   GLN GLN C . n 
C 1 10  ASP 10  10  10  ASP ASP C . n 
C 1 11  ARG 11  11  11  ARG ARG C . n 
C 1 12  LEU 12  12  12  LEU LEU C . n 
C 1 13  THR 13  13  13  THR THR C . n 
C 1 14  PRO 14  14  14  PRO PRO C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  LYS 17  17  17  LYS LYS C . n 
C 1 18  HIS 18  18  18  HIS HIS C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  VAL 20  20  20  VAL VAL C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  LYS 22  22  22  LYS LYS C . n 
C 1 23  ALA 23  23  23  ALA ALA C . n 
C 1 24  ILE 24  24  24  ILE ILE C . n 
C 1 25  THR 25  25  25  THR THR C . n 
C 1 26  ASP 26  26  26  ASP ASP C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  HIS 28  28  28  HIS HIS C . n 
C 1 29  ARG 29  29  29  ARG ARG C . n 
C 1 30  GLY 30  30  30  GLY GLY C . n 
C 1 31  LEU 31  31  31  LEU LEU C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  GLY 33  33  33  GLY GLY C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  HIS 36  36  36  HIS HIS C . n 
C 1 37  PHE 37  37  37  PHE PHE C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  ALA 39  39  39  ALA ALA C . n 
C 1 40  GLN 40  40  40  GLN GLN C . n 
C 1 41  VAL 41  41  41  VAL VAL C . n 
C 1 42  ASN 42  42  42  ASN ASN C . n 
C 1 43  PHE 43  43  43  PHE PHE C . n 
C 1 44  GLN 44  44  44  GLN GLN C . n 
C 1 45  GLU 45  45  45  GLU GLU C . n 
C 1 46  GLN 46  46  46  GLN GLN C . n 
C 1 47  PRO 47  47  47  PRO PRO C . n 
C 1 48  ALA 48  48  48  ALA ALA C . n 
C 1 49  GLY 49  49  49  GLY GLY C . n 
C 1 50  ASN 50  50  50  ASN ASN C . n 
C 1 51  VAL 51  51  51  VAL VAL C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  LEU 53  53  53  LEU LEU C . n 
C 1 54  GLY 54  54  54  GLY GLY C . n 
C 1 55  GLY 55  55  55  GLY GLY C . n 
C 1 56  VAL 56  56  56  VAL VAL C . n 
C 1 57  GLN 57  57  57  GLN GLN C . n 
C 1 58  GLN 58  58  58  GLN GLN C . n 
C 1 59  GLY 59  59  59  GLY GLY C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  ASP 61  61  61  ASP ASP C . n 
C 1 62  THR 62  62  62  THR THR C . n 
C 1 63  ILE 63  63  63  ILE ILE C . n 
C 1 64  PHE 64  64  64  PHE PHE C . n 
C 1 65  VAL 65  65  65  VAL VAL C . n 
C 1 66  HIS 66  66  66  HIS HIS C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  HIS 69  69  69  HIS HIS C . n 
C 1 70  ARG 70  70  70  ARG ARG C . n 
C 1 71  GLU 71  71  71  GLU GLU C . n 
C 1 72  GLY 72  72  72  GLY GLY C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  SER 74  74  74  SER SER C . n 
C 1 75  ALA 75  75  75  ALA ALA C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  LEU 77  77  77  LEU LEU C . n 
C 1 78  LYS 78  78  78  LYS LYS C . n 
C 1 79  GLY 79  79  79  GLY GLY C . n 
C 1 80  GLN 80  80  80  GLN GLN C . n 
C 1 81  LEU 81  81  81  LEU LEU C . n 
C 1 82  ALA 82  82  82  ALA ALA C . n 
C 1 83  GLN 83  83  83  GLN GLN C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  ILE 85  85  85  ILE ILE C . n 
C 1 86  VAL 86  86  86  VAL VAL C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  ASP 88  88  88  ASP ASP C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  SER 90  90  90  SER SER C . n 
C 1 91  VAL 91  91  91  VAL VAL C . n 
C 1 92  ALA 92  92  92  ALA ALA C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  GLU 94  94  94  GLU GLU C . n 
C 1 95  ILE 95  95  95  ILE ILE C . n 
C 1 96  ASP 96  96  96  ASP ASP C . n 
C 1 97  ARG 97  97  97  ARG ARG C . n 
C 1 98  LYS 98  98  98  LYS LYS C . n 
C 1 99  HIS 99  99  99  HIS HIS C . n 
C 1 100 ILE 100 100 100 ILE ILE C . n 
C 1 101 TRP 101 101 101 TRP TRP C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 TYR 103 103 103 TYR TYR C . n 
C 1 104 PHE 104 104 104 PHE PHE C . n 
C 1 105 GLY 105 105 105 GLY GLY C . n 
C 1 106 GLU 106 106 106 GLU GLU C . n 
C 1 107 MET 107 107 107 MET MET C . n 
C 1 108 PRO 108 108 108 PRO PRO C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 GLN 110 110 110 GLN GLN C . n 
C 1 111 GLN 111 111 111 GLN GLN C . n 
C 1 112 MET 112 112 112 MET MET C . n 
C 1 113 VAL 113 113 113 VAL VAL C . n 
C 1 114 GLN 114 114 114 GLN GLN C . n 
C 1 115 TYR 115 115 115 TYR TYR C . n 
C 1 116 GLY 116 116 116 GLY GLY C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 PHE 118 118 118 PHE PHE C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 PRO 120 120 120 PRO PRO C . n 
C 1 121 GLN 121 121 121 GLN GLN C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLY 123 123 123 GLY GLY C . n 
C 1 124 HIS 124 124 124 HIS HIS C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 GLY 126 126 126 GLY GLY C . n 
C 1 127 GLU 127 127 127 GLU GLU C . n 
C 1 128 TRP 128 128 128 TRP TRP C . n 
C 1 129 PHE 129 129 129 PHE PHE C . n 
C 1 130 ASP 130 130 130 ASP ASP C . n 
C 1 131 ASN 131 131 131 ASN ASN C . n 
C 1 132 LEU 132 132 132 LEU LEU C . n 
C 1 133 SER 133 133 133 SER SER C . n 
C 1 134 SER 134 134 134 SER SER C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 GLU 136 136 136 GLU GLU C . n 
C 1 137 ARG 137 137 137 ARG ARG C . n 
C 1 138 ALA 138 138 138 ALA ALA C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 MET 140 140 140 MET MET C . n 
C 1 141 GLU 141 141 141 GLU GLU C . n 
C 1 142 THR 142 142 142 THR THR C . n 
C 1 143 ASN 143 143 143 ASN ASN C . n 
C 1 144 VAL 144 144 144 VAL VAL C . n 
C 1 145 ASP 145 145 145 ASP ASP C . n 
C 1 146 VAL 146 146 ?   ?   ?   C . n 
C 1 147 SER 147 147 ?   ?   ?   C . n 
C 1 148 ARG 148 148 ?   ?   ?   C . n 
C 1 149 THR 149 149 ?   ?   ?   C . n 
C 1 150 GLU 150 150 ?   ?   ?   C . n 
C 1 151 ASN 151 151 ?   ?   ?   C . n 
C 1 152 LEU 152 152 ?   ?   ?   C . n 
C 1 153 TYR 153 153 ?   ?   ?   C . n 
C 1 154 PHE 154 154 ?   ?   ?   C . n 
C 1 155 GLN 155 155 ?   ?   ?   C . n 
C 1 156 GLY 156 156 ?   ?   ?   C . n 
C 1 157 LEU 157 157 ?   ?   ?   C . n 
C 1 158 GLU 158 158 ?   ?   ?   C . n 
C 1 159 HIS 159 159 ?   ?   ?   C . n 
C 1 160 HIS 160 160 ?   ?   ?   C . n 
C 1 161 HIS 161 161 ?   ?   ?   C . n 
C 1 162 HIS 162 162 ?   ?   ?   C . n 
C 1 163 HIS 163 163 ?   ?   ?   C . n 
C 1 164 HIS 164 164 ?   ?   ?   C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 PO4 1   201 1   PO4 PO4 A . 
E 2 PO4 1   201 2   PO4 PO4 B . 
F 2 PO4 1   201 3   PO4 PO4 C . 
G 3 HOH 1   301 196 HOH HOH A . 
G 3 HOH 2   302 128 HOH HOH A . 
G 3 HOH 3   303 58  HOH HOH A . 
G 3 HOH 4   304 158 HOH HOH A . 
G 3 HOH 5   305 289 HOH HOH A . 
G 3 HOH 6   306 67  HOH HOH A . 
G 3 HOH 7   307 102 HOH HOH A . 
G 3 HOH 8   308 354 HOH HOH A . 
G 3 HOH 9   309 349 HOH HOH A . 
G 3 HOH 10  310 170 HOH HOH A . 
G 3 HOH 11  311 162 HOH HOH A . 
G 3 HOH 12  312 38  HOH HOH A . 
G 3 HOH 13  313 30  HOH HOH A . 
G 3 HOH 14  314 208 HOH HOH A . 
G 3 HOH 15  315 118 HOH HOH A . 
G 3 HOH 16  316 278 HOH HOH A . 
G 3 HOH 17  317 124 HOH HOH A . 
G 3 HOH 18  318 11  HOH HOH A . 
G 3 HOH 19  319 310 HOH HOH A . 
G 3 HOH 20  320 86  HOH HOH A . 
G 3 HOH 21  321 182 HOH HOH A . 
G 3 HOH 22  322 159 HOH HOH A . 
G 3 HOH 23  323 91  HOH HOH A . 
G 3 HOH 24  324 107 HOH HOH A . 
G 3 HOH 25  325 213 HOH HOH A . 
G 3 HOH 26  326 255 HOH HOH A . 
G 3 HOH 27  327 126 HOH HOH A . 
G 3 HOH 28  328 8   HOH HOH A . 
G 3 HOH 29  329 75  HOH HOH A . 
G 3 HOH 30  330 271 HOH HOH A . 
G 3 HOH 31  331 103 HOH HOH A . 
G 3 HOH 32  332 111 HOH HOH A . 
G 3 HOH 33  333 6   HOH HOH A . 
G 3 HOH 34  334 319 HOH HOH A . 
G 3 HOH 35  335 52  HOH HOH A . 
G 3 HOH 36  336 176 HOH HOH A . 
G 3 HOH 37  337 136 HOH HOH A . 
G 3 HOH 38  338 226 HOH HOH A . 
G 3 HOH 39  339 205 HOH HOH A . 
G 3 HOH 40  340 193 HOH HOH A . 
G 3 HOH 41  341 112 HOH HOH A . 
G 3 HOH 42  342 50  HOH HOH A . 
G 3 HOH 43  343 36  HOH HOH A . 
G 3 HOH 44  344 26  HOH HOH A . 
G 3 HOH 45  345 382 HOH HOH A . 
G 3 HOH 46  346 117 HOH HOH A . 
G 3 HOH 47  347 198 HOH HOH A . 
G 3 HOH 48  348 138 HOH HOH A . 
G 3 HOH 49  349 153 HOH HOH A . 
G 3 HOH 50  350 72  HOH HOH A . 
G 3 HOH 51  351 7   HOH HOH A . 
G 3 HOH 52  352 33  HOH HOH A . 
G 3 HOH 53  353 5   HOH HOH A . 
G 3 HOH 54  354 141 HOH HOH A . 
G 3 HOH 55  355 100 HOH HOH A . 
G 3 HOH 56  356 48  HOH HOH A . 
G 3 HOH 57  357 74  HOH HOH A . 
G 3 HOH 58  358 45  HOH HOH A . 
G 3 HOH 59  359 119 HOH HOH A . 
G 3 HOH 60  360 127 HOH HOH A . 
G 3 HOH 61  361 151 HOH HOH A . 
G 3 HOH 62  362 53  HOH HOH A . 
G 3 HOH 63  363 87  HOH HOH A . 
G 3 HOH 64  364 367 HOH HOH A . 
G 3 HOH 65  365 347 HOH HOH A . 
G 3 HOH 66  366 104 HOH HOH A . 
G 3 HOH 67  367 305 HOH HOH A . 
G 3 HOH 68  368 171 HOH HOH A . 
G 3 HOH 69  369 90  HOH HOH A . 
G 3 HOH 70  370 194 HOH HOH A . 
G 3 HOH 71  371 81  HOH HOH A . 
G 3 HOH 72  372 92  HOH HOH A . 
G 3 HOH 73  373 110 HOH HOH A . 
G 3 HOH 74  374 144 HOH HOH A . 
G 3 HOH 75  375 288 HOH HOH A . 
G 3 HOH 76  376 172 HOH HOH A . 
G 3 HOH 77  377 132 HOH HOH A . 
G 3 HOH 78  378 27  HOH HOH A . 
G 3 HOH 79  379 85  HOH HOH A . 
G 3 HOH 80  380 234 HOH HOH A . 
G 3 HOH 81  381 270 HOH HOH A . 
G 3 HOH 82  382 95  HOH HOH A . 
G 3 HOH 83  383 188 HOH HOH A . 
G 3 HOH 84  384 41  HOH HOH A . 
G 3 HOH 85  385 24  HOH HOH A . 
G 3 HOH 86  386 321 HOH HOH A . 
G 3 HOH 87  387 179 HOH HOH A . 
G 3 HOH 88  388 211 HOH HOH A . 
G 3 HOH 89  389 185 HOH HOH A . 
G 3 HOH 90  390 184 HOH HOH A . 
G 3 HOH 91  391 337 HOH HOH A . 
G 3 HOH 92  392 373 HOH HOH A . 
G 3 HOH 93  393 56  HOH HOH A . 
G 3 HOH 94  394 225 HOH HOH A . 
G 3 HOH 95  395 268 HOH HOH A . 
G 3 HOH 96  396 180 HOH HOH A . 
G 3 HOH 97  397 120 HOH HOH A . 
G 3 HOH 98  398 199 HOH HOH A . 
G 3 HOH 99  399 332 HOH HOH A . 
G 3 HOH 100 400 262 HOH HOH A . 
G 3 HOH 101 401 363 HOH HOH A . 
G 3 HOH 102 402 140 HOH HOH A . 
G 3 HOH 103 403 76  HOH HOH A . 
G 3 HOH 104 404 340 HOH HOH A . 
G 3 HOH 105 405 385 HOH HOH A . 
G 3 HOH 106 406 264 HOH HOH A . 
G 3 HOH 107 407 267 HOH HOH A . 
G 3 HOH 108 408 358 HOH HOH A . 
G 3 HOH 109 409 300 HOH HOH A . 
G 3 HOH 110 410 242 HOH HOH A . 
G 3 HOH 111 411 376 HOH HOH A . 
G 3 HOH 112 412 137 HOH HOH A . 
G 3 HOH 113 413 84  HOH HOH A . 
G 3 HOH 114 414 247 HOH HOH A . 
G 3 HOH 115 415 294 HOH HOH A . 
G 3 HOH 116 416 260 HOH HOH A . 
G 3 HOH 117 417 371 HOH HOH A . 
G 3 HOH 118 418 322 HOH HOH A . 
G 3 HOH 119 419 245 HOH HOH A . 
G 3 HOH 120 420 315 HOH HOH A . 
G 3 HOH 121 421 301 HOH HOH A . 
G 3 HOH 122 422 284 HOH HOH A . 
G 3 HOH 123 423 209 HOH HOH A . 
G 3 HOH 124 424 282 HOH HOH A . 
G 3 HOH 125 425 333 HOH HOH A . 
G 3 HOH 126 426 329 HOH HOH A . 
G 3 HOH 127 427 177 HOH HOH A . 
G 3 HOH 128 428 241 HOH HOH A . 
G 3 HOH 129 429 143 HOH HOH A . 
G 3 HOH 130 430 212 HOH HOH A . 
G 3 HOH 131 431 330 HOH HOH A . 
G 3 HOH 132 432 338 HOH HOH A . 
G 3 HOH 133 433 219 HOH HOH A . 
G 3 HOH 134 434 381 HOH HOH A . 
G 3 HOH 135 435 178 HOH HOH A . 
G 3 HOH 136 436 361 HOH HOH A . 
G 3 HOH 137 437 365 HOH HOH A . 
H 3 HOH 1   301 122 HOH HOH B . 
H 3 HOH 2   302 274 HOH HOH B . 
H 3 HOH 3   303 217 HOH HOH B . 
H 3 HOH 4   304 69  HOH HOH B . 
H 3 HOH 5   305 114 HOH HOH B . 
H 3 HOH 6   306 297 HOH HOH B . 
H 3 HOH 7   307 192 HOH HOH B . 
H 3 HOH 8   308 320 HOH HOH B . 
H 3 HOH 9   309 239 HOH HOH B . 
H 3 HOH 10  310 331 HOH HOH B . 
H 3 HOH 11  311 206 HOH HOH B . 
H 3 HOH 12  312 125 HOH HOH B . 
H 3 HOH 13  313 202 HOH HOH B . 
H 3 HOH 14  314 22  HOH HOH B . 
H 3 HOH 15  315 142 HOH HOH B . 
H 3 HOH 16  316 183 HOH HOH B . 
H 3 HOH 17  317 246 HOH HOH B . 
H 3 HOH 18  318 156 HOH HOH B . 
H 3 HOH 19  319 296 HOH HOH B . 
H 3 HOH 20  320 73  HOH HOH B . 
H 3 HOH 21  321 168 HOH HOH B . 
H 3 HOH 22  322 149 HOH HOH B . 
H 3 HOH 23  323 222 HOH HOH B . 
H 3 HOH 24  324 248 HOH HOH B . 
H 3 HOH 25  325 105 HOH HOH B . 
H 3 HOH 26  326 89  HOH HOH B . 
H 3 HOH 27  327 228 HOH HOH B . 
H 3 HOH 28  328 109 HOH HOH B . 
H 3 HOH 29  329 34  HOH HOH B . 
H 3 HOH 30  330 23  HOH HOH B . 
H 3 HOH 31  331 80  HOH HOH B . 
H 3 HOH 32  332 68  HOH HOH B . 
H 3 HOH 33  333 15  HOH HOH B . 
H 3 HOH 34  334 13  HOH HOH B . 
H 3 HOH 35  335 360 HOH HOH B . 
H 3 HOH 36  336 200 HOH HOH B . 
H 3 HOH 37  337 285 HOH HOH B . 
H 3 HOH 38  338 60  HOH HOH B . 
H 3 HOH 39  339 9   HOH HOH B . 
H 3 HOH 40  340 35  HOH HOH B . 
H 3 HOH 41  341 147 HOH HOH B . 
H 3 HOH 42  342 346 HOH HOH B . 
H 3 HOH 43  343 21  HOH HOH B . 
H 3 HOH 44  344 70  HOH HOH B . 
H 3 HOH 45  345 207 HOH HOH B . 
H 3 HOH 46  346 356 HOH HOH B . 
H 3 HOH 47  347 106 HOH HOH B . 
H 3 HOH 48  348 157 HOH HOH B . 
H 3 HOH 49  349 221 HOH HOH B . 
H 3 HOH 50  350 17  HOH HOH B . 
H 3 HOH 51  351 224 HOH HOH B . 
H 3 HOH 52  352 263 HOH HOH B . 
H 3 HOH 53  353 57  HOH HOH B . 
H 3 HOH 54  354 99  HOH HOH B . 
H 3 HOH 55  355 39  HOH HOH B . 
H 3 HOH 56  356 115 HOH HOH B . 
H 3 HOH 57  357 37  HOH HOH B . 
H 3 HOH 58  358 165 HOH HOH B . 
H 3 HOH 59  359 152 HOH HOH B . 
H 3 HOH 60  360 97  HOH HOH B . 
H 3 HOH 61  361 116 HOH HOH B . 
H 3 HOH 62  362 175 HOH HOH B . 
H 3 HOH 63  363 230 HOH HOH B . 
H 3 HOH 64  364 237 HOH HOH B . 
H 3 HOH 65  365 286 HOH HOH B . 
H 3 HOH 66  366 218 HOH HOH B . 
H 3 HOH 67  367 257 HOH HOH B . 
H 3 HOH 68  368 328 HOH HOH B . 
H 3 HOH 69  369 129 HOH HOH B . 
H 3 HOH 70  370 252 HOH HOH B . 
H 3 HOH 71  371 362 HOH HOH B . 
H 3 HOH 72  372 169 HOH HOH B . 
H 3 HOH 73  373 2   HOH HOH B . 
H 3 HOH 74  374 269 HOH HOH B . 
H 3 HOH 75  375 201 HOH HOH B . 
H 3 HOH 76  376 345 HOH HOH B . 
H 3 HOH 77  377 63  HOH HOH B . 
H 3 HOH 78  378 287 HOH HOH B . 
H 3 HOH 79  379 101 HOH HOH B . 
H 3 HOH 80  380 324 HOH HOH B . 
H 3 HOH 81  381 163 HOH HOH B . 
H 3 HOH 82  382 51  HOH HOH B . 
H 3 HOH 83  383 302 HOH HOH B . 
H 3 HOH 84  384 187 HOH HOH B . 
H 3 HOH 85  385 303 HOH HOH B . 
H 3 HOH 86  386 47  HOH HOH B . 
H 3 HOH 87  387 1   HOH HOH B . 
H 3 HOH 88  388 220 HOH HOH B . 
H 3 HOH 89  389 341 HOH HOH B . 
H 3 HOH 90  390 148 HOH HOH B . 
H 3 HOH 91  391 83  HOH HOH B . 
H 3 HOH 92  392 93  HOH HOH B . 
H 3 HOH 93  393 139 HOH HOH B . 
H 3 HOH 94  394 189 HOH HOH B . 
H 3 HOH 95  395 155 HOH HOH B . 
H 3 HOH 96  396 258 HOH HOH B . 
H 3 HOH 97  397 19  HOH HOH B . 
H 3 HOH 98  398 235 HOH HOH B . 
H 3 HOH 99  399 256 HOH HOH B . 
H 3 HOH 100 400 314 HOH HOH B . 
H 3 HOH 101 401 364 HOH HOH B . 
H 3 HOH 102 402 160 HOH HOH B . 
H 3 HOH 103 403 309 HOH HOH B . 
H 3 HOH 104 404 359 HOH HOH B . 
H 3 HOH 105 405 369 HOH HOH B . 
H 3 HOH 106 406 238 HOH HOH B . 
H 3 HOH 107 407 343 HOH HOH B . 
H 3 HOH 108 408 306 HOH HOH B . 
H 3 HOH 109 409 273 HOH HOH B . 
H 3 HOH 110 410 334 HOH HOH B . 
H 3 HOH 111 411 336 HOH HOH B . 
H 3 HOH 112 412 94  HOH HOH B . 
H 3 HOH 113 413 372 HOH HOH B . 
H 3 HOH 114 414 173 HOH HOH B . 
H 3 HOH 115 415 353 HOH HOH B . 
H 3 HOH 116 416 378 HOH HOH B . 
H 3 HOH 117 417 243 HOH HOH B . 
H 3 HOH 118 418 244 HOH HOH B . 
H 3 HOH 119 419 161 HOH HOH B . 
H 3 HOH 120 420 283 HOH HOH B . 
H 3 HOH 121 421 350 HOH HOH B . 
H 3 HOH 122 422 304 HOH HOH B . 
H 3 HOH 123 423 357 HOH HOH B . 
H 3 HOH 124 424 166 HOH HOH B . 
H 3 HOH 125 425 383 HOH HOH B . 
H 3 HOH 126 426 215 HOH HOH B . 
H 3 HOH 127 427 377 HOH HOH B . 
H 3 HOH 128 428 348 HOH HOH B . 
H 3 HOH 129 429 233 HOH HOH B . 
H 3 HOH 130 430 131 HOH HOH B . 
H 3 HOH 131 431 342 HOH HOH B . 
H 3 HOH 132 432 281 HOH HOH B . 
H 3 HOH 133 433 317 HOH HOH B . 
H 3 HOH 134 434 295 HOH HOH B . 
I 3 HOH 1   301 154 HOH HOH C . 
I 3 HOH 2   302 275 HOH HOH C . 
I 3 HOH 3   303 290 HOH HOH C . 
I 3 HOH 4   304 323 HOH HOH C . 
I 3 HOH 5   305 88  HOH HOH C . 
I 3 HOH 6   306 150 HOH HOH C . 
I 3 HOH 7   307 293 HOH HOH C . 
I 3 HOH 8   308 77  HOH HOH C . 
I 3 HOH 9   309 130 HOH HOH C . 
I 3 HOH 10  310 279 HOH HOH C . 
I 3 HOH 11  311 352 HOH HOH C . 
I 3 HOH 12  312 79  HOH HOH C . 
I 3 HOH 13  313 253 HOH HOH C . 
I 3 HOH 14  314 167 HOH HOH C . 
I 3 HOH 15  315 292 HOH HOH C . 
I 3 HOH 16  316 384 HOH HOH C . 
I 3 HOH 17  317 3   HOH HOH C . 
I 3 HOH 18  318 16  HOH HOH C . 
I 3 HOH 19  319 308 HOH HOH C . 
I 3 HOH 20  320 164 HOH HOH C . 
I 3 HOH 21  321 339 HOH HOH C . 
I 3 HOH 22  322 4   HOH HOH C . 
I 3 HOH 23  323 43  HOH HOH C . 
I 3 HOH 24  324 31  HOH HOH C . 
I 3 HOH 25  325 28  HOH HOH C . 
I 3 HOH 26  326 186 HOH HOH C . 
I 3 HOH 27  327 229 HOH HOH C . 
I 3 HOH 28  328 307 HOH HOH C . 
I 3 HOH 29  329 174 HOH HOH C . 
I 3 HOH 30  330 335 HOH HOH C . 
I 3 HOH 31  331 108 HOH HOH C . 
I 3 HOH 32  332 40  HOH HOH C . 
I 3 HOH 33  333 66  HOH HOH C . 
I 3 HOH 34  334 20  HOH HOH C . 
I 3 HOH 35  335 18  HOH HOH C . 
I 3 HOH 36  336 231 HOH HOH C . 
I 3 HOH 37  337 113 HOH HOH C . 
I 3 HOH 38  338 96  HOH HOH C . 
I 3 HOH 39  339 135 HOH HOH C . 
I 3 HOH 40  340 251 HOH HOH C . 
I 3 HOH 41  341 49  HOH HOH C . 
I 3 HOH 42  342 318 HOH HOH C . 
I 3 HOH 43  343 29  HOH HOH C . 
I 3 HOH 44  344 232 HOH HOH C . 
I 3 HOH 45  345 78  HOH HOH C . 
I 3 HOH 46  346 272 HOH HOH C . 
I 3 HOH 47  347 14  HOH HOH C . 
I 3 HOH 48  348 298 HOH HOH C . 
I 3 HOH 49  349 25  HOH HOH C . 
I 3 HOH 50  350 55  HOH HOH C . 
I 3 HOH 51  351 98  HOH HOH C . 
I 3 HOH 52  352 32  HOH HOH C . 
I 3 HOH 53  353 316 HOH HOH C . 
I 3 HOH 54  354 214 HOH HOH C . 
I 3 HOH 55  355 313 HOH HOH C . 
I 3 HOH 56  356 54  HOH HOH C . 
I 3 HOH 57  357 123 HOH HOH C . 
I 3 HOH 58  358 10  HOH HOH C . 
I 3 HOH 59  359 191 HOH HOH C . 
I 3 HOH 60  360 42  HOH HOH C . 
I 3 HOH 61  361 134 HOH HOH C . 
I 3 HOH 62  362 65  HOH HOH C . 
I 3 HOH 63  363 61  HOH HOH C . 
I 3 HOH 64  364 64  HOH HOH C . 
I 3 HOH 65  365 311 HOH HOH C . 
I 3 HOH 66  366 203 HOH HOH C . 
I 3 HOH 67  367 370 HOH HOH C . 
I 3 HOH 68  368 12  HOH HOH C . 
I 3 HOH 69  369 216 HOH HOH C . 
I 3 HOH 70  370 62  HOH HOH C . 
I 3 HOH 71  371 379 HOH HOH C . 
I 3 HOH 72  372 46  HOH HOH C . 
I 3 HOH 73  373 71  HOH HOH C . 
I 3 HOH 74  374 312 HOH HOH C . 
I 3 HOH 75  375 190 HOH HOH C . 
I 3 HOH 76  376 210 HOH HOH C . 
I 3 HOH 77  377 197 HOH HOH C . 
I 3 HOH 78  378 326 HOH HOH C . 
I 3 HOH 79  379 145 HOH HOH C . 
I 3 HOH 80  380 261 HOH HOH C . 
I 3 HOH 81  381 146 HOH HOH C . 
I 3 HOH 82  382 277 HOH HOH C . 
I 3 HOH 83  383 227 HOH HOH C . 
I 3 HOH 84  384 249 HOH HOH C . 
I 3 HOH 85  385 59  HOH HOH C . 
I 3 HOH 86  386 368 HOH HOH C . 
I 3 HOH 87  387 327 HOH HOH C . 
I 3 HOH 88  388 240 HOH HOH C . 
I 3 HOH 89  389 181 HOH HOH C . 
I 3 HOH 90  390 386 HOH HOH C . 
I 3 HOH 91  391 325 HOH HOH C . 
I 3 HOH 92  392 195 HOH HOH C . 
I 3 HOH 93  393 344 HOH HOH C . 
I 3 HOH 94  394 254 HOH HOH C . 
I 3 HOH 95  395 133 HOH HOH C . 
I 3 HOH 96  396 250 HOH HOH C . 
I 3 HOH 97  397 204 HOH HOH C . 
I 3 HOH 98  398 380 HOH HOH C . 
I 3 HOH 99  399 375 HOH HOH C . 
I 3 HOH 100 400 121 HOH HOH C . 
I 3 HOH 101 401 299 HOH HOH C . 
I 3 HOH 102 402 44  HOH HOH C . 
I 3 HOH 103 403 236 HOH HOH C . 
I 3 HOH 104 404 266 HOH HOH C . 
I 3 HOH 105 405 387 HOH HOH C . 
I 3 HOH 106 406 259 HOH HOH C . 
I 3 HOH 107 407 280 HOH HOH C . 
I 3 HOH 108 408 351 HOH HOH C . 
I 3 HOH 109 409 291 HOH HOH C . 
I 3 HOH 110 410 276 HOH HOH C . 
I 3 HOH 111 411 82  HOH HOH C . 
I 3 HOH 112 412 374 HOH HOH C . 
I 3 HOH 113 413 223 HOH HOH C . 
I 3 HOH 114 414 355 HOH HOH C . 
I 3 HOH 115 415 265 HOH HOH C . 
I 3 HOH 116 416 366 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NGL 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     59.977 
_cell.length_a_esd                 ? 
_cell.length_b                     101.078 
_cell.length_b_esd                 ? 
_cell.length_c                     144.071 
_cell.length_c_esd                 ? 
_cell.volume                       873409.577 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NGL 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NGL 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.96 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          37.25 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '(0.05 M citric acid, 0.05 M BIS-TRIS propane) pH 5 20% w/v PEG 3,354' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-29 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.13 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 21-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.13 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   21-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          18.84 
_reflns.entry_id                                       9NGL 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.80 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     40869 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.5 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                9.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          27.89 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.026 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.80 
_reflns_shell.d_res_low                                     1.83 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2024 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.204 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               20.40 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NGL 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.80 
_refine.ls_d_res_low                             29.53 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     40688 
_refine.ls_number_reflns_R_free                  1996 
_refine.ls_number_reflns_R_work                  38692 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.09 
_refine.ls_percent_reflns_R_free                 4.91 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1755 
_refine.ls_R_factor_R_free                       0.2153 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1734 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 19.1833 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1956 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.80 
_refine_hist.d_res_low                        29.53 
_refine_hist.number_atoms_solvent             387 
_refine_hist.number_atoms_total               3835 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3433 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         15 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0070 ? 3551 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9955 ? 4811 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0675 ? 499  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0085 ? 645  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 5.4626 ? 474  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.80 1.84  . . 143 2692 97.42 . . . . 0.2526 . . . . . . . . . . . . . . . 0.3213 
'X-RAY DIFFRACTION' 1.84 1.89  . . 135 2682 97.20 . . . . 0.2116 . . . . . . . . . . . . . . . 0.2536 
'X-RAY DIFFRACTION' 1.89 1.95  . . 138 2723 98.76 . . . . 0.1812 . . . . . . . . . . . . . . . 0.2158 
'X-RAY DIFFRACTION' 1.95 2.01  . . 141 2745 99.79 . . . . 0.1777 . . . . . . . . . . . . . . . 0.2002 
'X-RAY DIFFRACTION' 2.01 2.08  . . 145 2737 99.45 . . . . 0.1760 . . . . . . . . . . . . . . . 0.2220 
'X-RAY DIFFRACTION' 2.08 2.17  . . 135 2765 99.76 . . . . 0.1861 . . . . . . . . . . . . . . . 0.2395 
'X-RAY DIFFRACTION' 2.17 2.27  . . 150 2746 99.52 . . . . 0.1704 . . . . . . . . . . . . . . . 0.2271 
'X-RAY DIFFRACTION' 2.27 2.39  . . 143 2759 99.93 . . . . 0.1686 . . . . . . . . . . . . . . . 0.2063 
'X-RAY DIFFRACTION' 2.39 2.53  . . 150 2771 99.66 . . . . 0.1779 . . . . . . . . . . . . . . . 0.2475 
'X-RAY DIFFRACTION' 2.54 2.73  . . 138 2793 99.86 . . . . 0.1786 . . . . . . . . . . . . . . . 0.2199 
'X-RAY DIFFRACTION' 2.73 3.00  . . 146 2789 99.86 . . . . 0.1790 . . . . . . . . . . . . . . . 0.2211 
'X-RAY DIFFRACTION' 3.01 3.44  . . 137 2758 97.87 . . . . 0.1755 . . . . . . . . . . . . . . . 0.2135 
'X-RAY DIFFRACTION' 3.44 4.33  . . 141 2807 99.13 . . . . 0.1422 . . . . . . . . . . . . . . . 0.1924 
'X-RAY DIFFRACTION' 4.33 29.53 . . 154 2925 99.07 . . . . 0.1718 . . . . . . . . . . . . . . . 0.1894 
# 
_struct.entry_id                     9NGL 
_struct.title                        'cis-CaaD E114Q' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NGL 
_struct_keywords.text            'Tautomerase, cis-CaaD, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q6VPE5_9CORY 
_struct_ref.pdbx_db_accession          Q6VPE5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVEYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRT
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NGL A 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
2 1 9NGL B 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
3 1 9NGL C 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9NGL GLN A 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 1  
1 9NGL GLU A 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 2  
1 9NGL ASN A 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 3  
1 9NGL LEU A 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 4  
1 9NGL TYR A 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 5  
1 9NGL PHE A 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 6  
1 9NGL GLN A 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 7  
1 9NGL GLY A 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 8  
1 9NGL LEU A 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 9  
1 9NGL GLU A 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 10 
1 9NGL HIS A 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 11 
1 9NGL HIS A 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 12 
1 9NGL HIS A 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 13 
1 9NGL HIS A 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 14 
1 9NGL HIS A 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 15 
1 9NGL HIS A 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 16 
2 9NGL GLN B 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 17 
2 9NGL GLU B 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 18 
2 9NGL ASN B 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 19 
2 9NGL LEU B 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 20 
2 9NGL TYR B 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 21 
2 9NGL PHE B 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 22 
2 9NGL GLN B 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 23 
2 9NGL GLY B 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 24 
2 9NGL LEU B 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 25 
2 9NGL GLU B 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 26 
2 9NGL HIS B 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 27 
2 9NGL HIS B 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 28 
2 9NGL HIS B 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 29 
2 9NGL HIS B 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 30 
2 9NGL HIS B 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 31 
2 9NGL HIS B 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 32 
3 9NGL GLN C 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 33 
3 9NGL GLU C 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 34 
3 9NGL ASN C 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 35 
3 9NGL LEU C 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 36 
3 9NGL TYR C 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 37 
3 9NGL PHE C 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 38 
3 9NGL GLN C 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 39 
3 9NGL GLY C 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 40 
3 9NGL LEU C 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 41 
3 9NGL GLU C 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 42 
3 9NGL HIS C 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 43 
3 9NGL HIS C 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 44 
3 9NGL HIS C 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 45 
3 9NGL HIS C 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 46 
3 9NGL HIS C 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 47 
3 9NGL HIS C 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 48 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 9030  ? 
1 MORE         -73   ? 
1 'SSA (A^2)'  15270 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 13  ? GLY A 33  ? THR A 13  GLY A 33  1 ? 21 
HELX_P HELX_P2  AA2 GLN A 35  ? LEU A 38  ? GLN A 35  LEU A 38  5 ? 4  
HELX_P HELX_P3  AA3 SER A 74  ? ALA A 93  ? SER A 74  ALA A 93  1 ? 20 
HELX_P HELX_P4  AA4 ASP A 96  ? LYS A 98  ? ASP A 96  LYS A 98  5 ? 3  
HELX_P HELX_P5  AA5 PRO A 108 ? GLN A 110 ? PRO A 108 GLN A 110 5 ? 3  
HELX_P HELX_P6  AA6 HIS A 124 ? ASN A 131 ? HIS A 124 ASN A 131 1 ? 8  
HELX_P HELX_P7  AA7 SER A 133 ? THR A 142 ? SER A 133 THR A 142 1 ? 10 
HELX_P HELX_P8  AA8 THR B 13  ? GLY B 33  ? THR B 13  GLY B 33  1 ? 21 
HELX_P HELX_P9  AA9 GLN B 35  ? LEU B 38  ? GLN B 35  LEU B 38  5 ? 4  
HELX_P HELX_P10 AB1 SER B 74  ? GLU B 94  ? SER B 74  GLU B 94  1 ? 21 
HELX_P HELX_P11 AB2 ASP B 96  ? LYS B 98  ? ASP B 96  LYS B 98  5 ? 3  
HELX_P HELX_P12 AB3 PRO B 108 ? GLN B 110 ? PRO B 108 GLN B 110 5 ? 3  
HELX_P HELX_P13 AB4 HIS B 124 ? ASN B 131 ? HIS B 124 ASN B 131 1 ? 8  
HELX_P HELX_P14 AB5 SER B 133 ? THR B 142 ? SER B 133 THR B 142 1 ? 10 
HELX_P HELX_P15 AB6 THR C 13  ? GLY C 33  ? THR C 13  GLY C 33  1 ? 21 
HELX_P HELX_P16 AB7 GLN C 35  ? LEU C 38  ? GLN C 35  LEU C 38  5 ? 4  
HELX_P HELX_P17 AB8 SER C 74  ? GLU C 94  ? SER C 74  GLU C 94  1 ? 21 
HELX_P HELX_P18 AB9 ASP C 96  ? LYS C 98  ? ASP C 96  LYS C 98  5 ? 3  
HELX_P HELX_P19 AC1 PRO C 108 ? GLN C 110 ? PRO C 108 GLN C 110 5 ? 3  
HELX_P HELX_P20 AC2 HIS C 124 ? ASN C 131 ? HIS C 124 ASN C 131 1 ? 8  
HELX_P HELX_P21 AC3 SER C 133 ? THR C 142 ? SER C 133 THR C 142 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 8 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
AA2 5 6 ? parallel      
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? anti-parallel 
AA3 5 6 ? parallel      
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL B 56  ? GLN B 57  ? VAL B 56  GLN B 57  
AA1 2 VAL B 51  ? LEU B 53  ? VAL B 51  LEU B 53  
AA1 3 GLN A 40  ? GLN A 46  ? GLN A 40  GLN A 46  
AA1 4 VAL A 2   ? SER A 8   ? VAL A 2   SER A 8   
AA1 5 ILE A 63  ? ARG A 70  ? ILE A 63  ARG A 70  
AA1 6 ILE A 100 ? MET A 107 ? ILE A 100 MET A 107 
AA1 7 MET C 112 ? GLN C 114 ? MET C 112 GLN C 114 
AA1 8 ARG C 117 ? PHE C 118 ? ARG C 117 PHE C 118 
AA2 1 VAL A 56  ? GLN A 57  ? VAL A 56  GLN A 57  
AA2 2 VAL A 51  ? LEU A 53  ? VAL A 51  LEU A 53  
AA2 3 GLN C 40  ? GLN C 46  ? GLN C 40  GLN C 46  
AA2 4 VAL C 2   ? SER C 8   ? VAL C 2   SER C 8   
AA2 5 ILE C 63  ? ARG C 70  ? ILE C 63  ARG C 70  
AA2 6 ILE C 100 ? MET C 107 ? ILE C 100 MET C 107 
AA2 7 MET B 112 ? GLN B 114 ? MET B 112 GLN B 114 
AA2 8 ARG B 117 ? PHE B 118 ? ARG B 117 PHE B 118 
AA3 1 ARG A 117 ? PHE A 118 ? ARG A 117 PHE A 118 
AA3 2 MET A 112 ? GLN A 114 ? MET A 112 GLN A 114 
AA3 3 ILE B 100 ? MET B 107 ? ILE B 100 MET B 107 
AA3 4 ILE B 63  ? ARG B 70  ? ILE B 63  ARG B 70  
AA3 5 VAL B 2   ? SER B 8   ? VAL B 2   SER B 8   
AA3 6 GLN B 40  ? GLN B 46  ? GLN B 40  GLN B 46  
AA3 7 VAL C 51  ? LEU C 53  ? VAL C 51  LEU C 53  
AA3 8 VAL C 56  ? GLN C 57  ? VAL C 56  GLN C 57  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O VAL B 56  ? O VAL B 56  N LEU B 53  ? N LEU B 53  
AA1 2 3 O PHE B 52  ? O PHE B 52  N VAL A 41  ? N VAL A 41  
AA1 3 4 O ASN A 42  ? O ASN A 42  N TYR A 3   ? N TYR A 3   
AA1 4 5 N TYR A 6   ? N TYR A 6   O PHE A 64  ? O PHE A 64  
AA1 5 6 N HIS A 69  ? N HIS A 69  O GLY A 105 ? O GLY A 105 
AA1 6 7 N VAL A 102 ? N VAL A 102 O VAL C 113 ? O VAL C 113 
AA1 7 8 N GLN C 114 ? N GLN C 114 O ARG C 117 ? O ARG C 117 
AA2 1 2 O VAL A 56  ? O VAL A 56  N LEU A 53  ? N LEU A 53  
AA2 2 3 N PHE A 52  ? N PHE A 52  O VAL C 41  ? O VAL C 41  
AA2 3 4 O GLN C 44  ? O GLN C 44  N VAL C 5   ? N VAL C 5   
AA2 4 5 N MET C 4   ? N MET C 4   O HIS C 66  ? O HIS C 66  
AA2 5 6 N HIS C 69  ? N HIS C 69  O GLY C 105 ? O GLY C 105 
AA2 6 7 O VAL C 102 ? O VAL C 102 N VAL B 113 ? N VAL B 113 
AA2 7 8 N GLN B 114 ? N GLN B 114 O ARG B 117 ? O ARG B 117 
AA3 1 2 O ARG A 117 ? O ARG A 117 N GLN A 114 ? N GLN A 114 
AA3 2 3 N VAL A 113 ? N VAL A 113 O VAL B 102 ? O VAL B 102 
AA3 3 4 O GLY B 105 ? O GLY B 105 N HIS B 69  ? N HIS B 69  
AA3 4 5 O HIS B 66  ? O HIS B 66  N MET B 4   ? N MET B 4   
AA3 5 6 N VAL B 5   ? N VAL B 5   O GLN B 44  ? O GLN B 44  
AA3 6 7 N VAL B 41  ? N VAL B 41  O PHE C 52  ? O PHE C 52  
AA3 7 8 N LEU C 53  ? N LEU C 53  O VAL C 56  ? O VAL C 56  
# 
_pdbx_entry_details.entry_id                   9NGL 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A HOH 354 ? ? O B HOH 424 ? ? 2.04 
2 1 OG  B SER 15  ? ? O B HOH 301 ? ? 2.04 
3 1 O   B HOH 311 ? ? O B HOH 421 ? ? 2.12 
4 1 O   B HOH 307 ? ? O B HOH 365 ? ? 2.16 
5 1 O   C HOH 353 ? ? O C HOH 407 ? ? 2.16 
6 1 OE2 A GLU 127 ? ? O A HOH 301 ? ? 2.18 
7 1 O   C HOH 344 ? ? O C HOH 404 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 10  ? ? 68.08   -5.31  
2 1 PRO A 122 ? ? -48.58  -8.24  
3 1 ASN A 143 ? ? -105.66 57.81  
4 1 ASN B 143 ? ? -97.34  58.94  
5 1 ASP C 10  ? ? 78.26   -6.49  
6 1 HIS C 36  ? ? -28.83  -58.88 
7 1 ASN C 143 ? ? -91.95  59.75  
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     375 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   G 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? B HOH 433 ? 6.60 . 
2 1 O ? B HOH 434 ? 7.10 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A VAL 146 ? A VAL 146 
2  1 Y 1 A SER 147 ? A SER 147 
3  1 Y 1 A ARG 148 ? A ARG 148 
4  1 Y 1 A THR 149 ? A THR 149 
5  1 Y 1 A GLU 150 ? A GLU 150 
6  1 Y 1 A ASN 151 ? A ASN 151 
7  1 Y 1 A LEU 152 ? A LEU 152 
8  1 Y 1 A TYR 153 ? A TYR 153 
9  1 Y 1 A PHE 154 ? A PHE 154 
10 1 Y 1 A GLN 155 ? A GLN 155 
11 1 Y 1 A GLY 156 ? A GLY 156 
12 1 Y 1 A LEU 157 ? A LEU 157 
13 1 Y 1 A GLU 158 ? A GLU 158 
14 1 Y 1 A HIS 159 ? A HIS 159 
15 1 Y 1 A HIS 160 ? A HIS 160 
16 1 Y 1 A HIS 161 ? A HIS 161 
17 1 Y 1 A HIS 162 ? A HIS 162 
18 1 Y 1 A HIS 163 ? A HIS 163 
19 1 Y 1 A HIS 164 ? A HIS 164 
20 1 Y 1 B SER 147 ? B SER 147 
21 1 Y 1 B ARG 148 ? B ARG 148 
22 1 Y 1 B THR 149 ? B THR 149 
23 1 Y 1 B GLU 150 ? B GLU 150 
24 1 Y 1 B ASN 151 ? B ASN 151 
25 1 Y 1 B LEU 152 ? B LEU 152 
26 1 Y 1 B TYR 153 ? B TYR 153 
27 1 Y 1 B PHE 154 ? B PHE 154 
28 1 Y 1 B GLN 155 ? B GLN 155 
29 1 Y 1 B GLY 156 ? B GLY 156 
30 1 Y 1 B LEU 157 ? B LEU 157 
31 1 Y 1 B GLU 158 ? B GLU 158 
32 1 Y 1 B HIS 159 ? B HIS 159 
33 1 Y 1 B HIS 160 ? B HIS 160 
34 1 Y 1 B HIS 161 ? B HIS 161 
35 1 Y 1 B HIS 162 ? B HIS 162 
36 1 Y 1 B HIS 163 ? B HIS 163 
37 1 Y 1 B HIS 164 ? B HIS 164 
38 1 Y 1 C VAL 146 ? C VAL 146 
39 1 Y 1 C SER 147 ? C SER 147 
40 1 Y 1 C ARG 148 ? C ARG 148 
41 1 Y 1 C THR 149 ? C THR 149 
42 1 Y 1 C GLU 150 ? C GLU 150 
43 1 Y 1 C ASN 151 ? C ASN 151 
44 1 Y 1 C LEU 152 ? C LEU 152 
45 1 Y 1 C TYR 153 ? C TYR 153 
46 1 Y 1 C PHE 154 ? C PHE 154 
47 1 Y 1 C GLN 155 ? C GLN 155 
48 1 Y 1 C GLY 156 ? C GLY 156 
49 1 Y 1 C LEU 157 ? C LEU 157 
50 1 Y 1 C GLU 158 ? C GLU 158 
51 1 Y 1 C HIS 159 ? C HIS 159 
52 1 Y 1 C HIS 160 ? C HIS 160 
53 1 Y 1 C HIS 161 ? C HIS 161 
54 1 Y 1 C HIS 162 ? C HIS 162 
55 1 Y 1 C HIS 163 ? C HIS 163 
56 1 Y 1 C HIS 164 ? C HIS 164 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
HOH O    O N N 144 
HOH H1   H N N 145 
HOH H2   H N N 146 
ILE N    N N N 147 
ILE CA   C N S 148 
ILE C    C N N 149 
ILE O    O N N 150 
ILE CB   C N S 151 
ILE CG1  C N N 152 
ILE CG2  C N N 153 
ILE CD1  C N N 154 
ILE OXT  O N N 155 
ILE H    H N N 156 
ILE H2   H N N 157 
ILE HA   H N N 158 
ILE HB   H N N 159 
ILE HG12 H N N 160 
ILE HG13 H N N 161 
ILE HG21 H N N 162 
ILE HG22 H N N 163 
ILE HG23 H N N 164 
ILE HD11 H N N 165 
ILE HD12 H N N 166 
ILE HD13 H N N 167 
ILE HXT  H N N 168 
LEU N    N N N 169 
LEU CA   C N S 170 
LEU C    C N N 171 
LEU O    O N N 172 
LEU CB   C N N 173 
LEU CG   C N N 174 
LEU CD1  C N N 175 
LEU CD2  C N N 176 
LEU OXT  O N N 177 
LEU H    H N N 178 
LEU H2   H N N 179 
LEU HA   H N N 180 
LEU HB2  H N N 181 
LEU HB3  H N N 182 
LEU HG   H N N 183 
LEU HD11 H N N 184 
LEU HD12 H N N 185 
LEU HD13 H N N 186 
LEU HD21 H N N 187 
LEU HD22 H N N 188 
LEU HD23 H N N 189 
LEU HXT  H N N 190 
LYS N    N N N 191 
LYS CA   C N S 192 
LYS C    C N N 193 
LYS O    O N N 194 
LYS CB   C N N 195 
LYS CG   C N N 196 
LYS CD   C N N 197 
LYS CE   C N N 198 
LYS NZ   N N N 199 
LYS OXT  O N N 200 
LYS H    H N N 201 
LYS H2   H N N 202 
LYS HA   H N N 203 
LYS HB2  H N N 204 
LYS HB3  H N N 205 
LYS HG2  H N N 206 
LYS HG3  H N N 207 
LYS HD2  H N N 208 
LYS HD3  H N N 209 
LYS HE2  H N N 210 
LYS HE3  H N N 211 
LYS HZ1  H N N 212 
LYS HZ2  H N N 213 
LYS HZ3  H N N 214 
LYS HXT  H N N 215 
MET N    N N N 216 
MET CA   C N S 217 
MET C    C N N 218 
MET O    O N N 219 
MET CB   C N N 220 
MET CG   C N N 221 
MET SD   S N N 222 
MET CE   C N N 223 
MET OXT  O N N 224 
MET H    H N N 225 
MET H2   H N N 226 
MET HA   H N N 227 
MET HB2  H N N 228 
MET HB3  H N N 229 
MET HG2  H N N 230 
MET HG3  H N N 231 
MET HE1  H N N 232 
MET HE2  H N N 233 
MET HE3  H N N 234 
MET HXT  H N N 235 
PHE N    N N N 236 
PHE CA   C N S 237 
PHE C    C N N 238 
PHE O    O N N 239 
PHE CB   C N N 240 
PHE CG   C Y N 241 
PHE CD1  C Y N 242 
PHE CD2  C Y N 243 
PHE CE1  C Y N 244 
PHE CE2  C Y N 245 
PHE CZ   C Y N 246 
PHE OXT  O N N 247 
PHE H    H N N 248 
PHE H2   H N N 249 
PHE HA   H N N 250 
PHE HB2  H N N 251 
PHE HB3  H N N 252 
PHE HD1  H N N 253 
PHE HD2  H N N 254 
PHE HE1  H N N 255 
PHE HE2  H N N 256 
PHE HZ   H N N 257 
PHE HXT  H N N 258 
PO4 P    P N N 259 
PO4 O1   O N N 260 
PO4 O2   O N N 261 
PO4 O3   O N N 262 
PO4 O4   O N N 263 
PRO N    N N N 264 
PRO CA   C N S 265 
PRO C    C N N 266 
PRO O    O N N 267 
PRO CB   C N N 268 
PRO CG   C N N 269 
PRO CD   C N N 270 
PRO OXT  O N N 271 
PRO H    H N N 272 
PRO HA   H N N 273 
PRO HB2  H N N 274 
PRO HB3  H N N 275 
PRO HG2  H N N 276 
PRO HG3  H N N 277 
PRO HD2  H N N 278 
PRO HD3  H N N 279 
PRO HXT  H N N 280 
SER N    N N N 281 
SER CA   C N S 282 
SER C    C N N 283 
SER O    O N N 284 
SER CB   C N N 285 
SER OG   O N N 286 
SER OXT  O N N 287 
SER H    H N N 288 
SER H2   H N N 289 
SER HA   H N N 290 
SER HB2  H N N 291 
SER HB3  H N N 292 
SER HG   H N N 293 
SER HXT  H N N 294 
THR N    N N N 295 
THR CA   C N S 296 
THR C    C N N 297 
THR O    O N N 298 
THR CB   C N R 299 
THR OG1  O N N 300 
THR CG2  C N N 301 
THR OXT  O N N 302 
THR H    H N N 303 
THR H2   H N N 304 
THR HA   H N N 305 
THR HB   H N N 306 
THR HG1  H N N 307 
THR HG21 H N N 308 
THR HG22 H N N 309 
THR HG23 H N N 310 
THR HXT  H N N 311 
TRP N    N N N 312 
TRP CA   C N S 313 
TRP C    C N N 314 
TRP O    O N N 315 
TRP CB   C N N 316 
TRP CG   C Y N 317 
TRP CD1  C Y N 318 
TRP CD2  C Y N 319 
TRP NE1  N Y N 320 
TRP CE2  C Y N 321 
TRP CE3  C Y N 322 
TRP CZ2  C Y N 323 
TRP CZ3  C Y N 324 
TRP CH2  C Y N 325 
TRP OXT  O N N 326 
TRP H    H N N 327 
TRP H2   H N N 328 
TRP HA   H N N 329 
TRP HB2  H N N 330 
TRP HB3  H N N 331 
TRP HD1  H N N 332 
TRP HE1  H N N 333 
TRP HE3  H N N 334 
TRP HZ2  H N N 335 
TRP HZ3  H N N 336 
TRP HH2  H N N 337 
TRP HXT  H N N 338 
TYR N    N N N 339 
TYR CA   C N S 340 
TYR C    C N N 341 
TYR O    O N N 342 
TYR CB   C N N 343 
TYR CG   C Y N 344 
TYR CD1  C Y N 345 
TYR CD2  C Y N 346 
TYR CE1  C Y N 347 
TYR CE2  C Y N 348 
TYR CZ   C Y N 349 
TYR OH   O N N 350 
TYR OXT  O N N 351 
TYR H    H N N 352 
TYR H2   H N N 353 
TYR HA   H N N 354 
TYR HB2  H N N 355 
TYR HB3  H N N 356 
TYR HD1  H N N 357 
TYR HD2  H N N 358 
TYR HE1  H N N 359 
TYR HE2  H N N 360 
TYR HH   H N N 361 
TYR HXT  H N N 362 
VAL N    N N N 363 
VAL CA   C N S 364 
VAL C    C N N 365 
VAL O    O N N 366 
VAL CB   C N N 367 
VAL CG1  C N N 368 
VAL CG2  C N N 369 
VAL OXT  O N N 370 
VAL H    H N N 371 
VAL H2   H N N 372 
VAL HA   H N N 373 
VAL HB   H N N 374 
VAL HG11 H N N 375 
VAL HG12 H N N 376 
VAL HG13 H N N 377 
VAL HG21 H N N 378 
VAL HG22 H N N 379 
VAL HG23 H N N 380 
VAL HXT  H N N 381 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
HOH O   H1   sing N N 137 
HOH O   H2   sing N N 138 
ILE N   CA   sing N N 139 
ILE N   H    sing N N 140 
ILE N   H2   sing N N 141 
ILE CA  C    sing N N 142 
ILE CA  CB   sing N N 143 
ILE CA  HA   sing N N 144 
ILE C   O    doub N N 145 
ILE C   OXT  sing N N 146 
ILE CB  CG1  sing N N 147 
ILE CB  CG2  sing N N 148 
ILE CB  HB   sing N N 149 
ILE CG1 CD1  sing N N 150 
ILE CG1 HG12 sing N N 151 
ILE CG1 HG13 sing N N 152 
ILE CG2 HG21 sing N N 153 
ILE CG2 HG22 sing N N 154 
ILE CG2 HG23 sing N N 155 
ILE CD1 HD11 sing N N 156 
ILE CD1 HD12 sing N N 157 
ILE CD1 HD13 sing N N 158 
ILE OXT HXT  sing N N 159 
LEU N   CA   sing N N 160 
LEU N   H    sing N N 161 
LEU N   H2   sing N N 162 
LEU CA  C    sing N N 163 
LEU CA  CB   sing N N 164 
LEU CA  HA   sing N N 165 
LEU C   O    doub N N 166 
LEU C   OXT  sing N N 167 
LEU CB  CG   sing N N 168 
LEU CB  HB2  sing N N 169 
LEU CB  HB3  sing N N 170 
LEU CG  CD1  sing N N 171 
LEU CG  CD2  sing N N 172 
LEU CG  HG   sing N N 173 
LEU CD1 HD11 sing N N 174 
LEU CD1 HD12 sing N N 175 
LEU CD1 HD13 sing N N 176 
LEU CD2 HD21 sing N N 177 
LEU CD2 HD22 sing N N 178 
LEU CD2 HD23 sing N N 179 
LEU OXT HXT  sing N N 180 
LYS N   CA   sing N N 181 
LYS N   H    sing N N 182 
LYS N   H2   sing N N 183 
LYS CA  C    sing N N 184 
LYS CA  CB   sing N N 185 
LYS CA  HA   sing N N 186 
LYS C   O    doub N N 187 
LYS C   OXT  sing N N 188 
LYS CB  CG   sing N N 189 
LYS CB  HB2  sing N N 190 
LYS CB  HB3  sing N N 191 
LYS CG  CD   sing N N 192 
LYS CG  HG2  sing N N 193 
LYS CG  HG3  sing N N 194 
LYS CD  CE   sing N N 195 
LYS CD  HD2  sing N N 196 
LYS CD  HD3  sing N N 197 
LYS CE  NZ   sing N N 198 
LYS CE  HE2  sing N N 199 
LYS CE  HE3  sing N N 200 
LYS NZ  HZ1  sing N N 201 
LYS NZ  HZ2  sing N N 202 
LYS NZ  HZ3  sing N N 203 
LYS OXT HXT  sing N N 204 
MET N   CA   sing N N 205 
MET N   H    sing N N 206 
MET N   H2   sing N N 207 
MET CA  C    sing N N 208 
MET CA  CB   sing N N 209 
MET CA  HA   sing N N 210 
MET C   O    doub N N 211 
MET C   OXT  sing N N 212 
MET CB  CG   sing N N 213 
MET CB  HB2  sing N N 214 
MET CB  HB3  sing N N 215 
MET CG  SD   sing N N 216 
MET CG  HG2  sing N N 217 
MET CG  HG3  sing N N 218 
MET SD  CE   sing N N 219 
MET CE  HE1  sing N N 220 
MET CE  HE2  sing N N 221 
MET CE  HE3  sing N N 222 
MET OXT HXT  sing N N 223 
PHE N   CA   sing N N 224 
PHE N   H    sing N N 225 
PHE N   H2   sing N N 226 
PHE CA  C    sing N N 227 
PHE CA  CB   sing N N 228 
PHE CA  HA   sing N N 229 
PHE C   O    doub N N 230 
PHE C   OXT  sing N N 231 
PHE CB  CG   sing N N 232 
PHE CB  HB2  sing N N 233 
PHE CB  HB3  sing N N 234 
PHE CG  CD1  doub Y N 235 
PHE CG  CD2  sing Y N 236 
PHE CD1 CE1  sing Y N 237 
PHE CD1 HD1  sing N N 238 
PHE CD2 CE2  doub Y N 239 
PHE CD2 HD2  sing N N 240 
PHE CE1 CZ   doub Y N 241 
PHE CE1 HE1  sing N N 242 
PHE CE2 CZ   sing Y N 243 
PHE CE2 HE2  sing N N 244 
PHE CZ  HZ   sing N N 245 
PHE OXT HXT  sing N N 246 
PO4 P   O1   doub N N 247 
PO4 P   O2   sing N N 248 
PO4 P   O3   sing N N 249 
PO4 P   O4   sing N N 250 
PRO N   CA   sing N N 251 
PRO N   CD   sing N N 252 
PRO N   H    sing N N 253 
PRO CA  C    sing N N 254 
PRO CA  CB   sing N N 255 
PRO CA  HA   sing N N 256 
PRO C   O    doub N N 257 
PRO C   OXT  sing N N 258 
PRO CB  CG   sing N N 259 
PRO CB  HB2  sing N N 260 
PRO CB  HB3  sing N N 261 
PRO CG  CD   sing N N 262 
PRO CG  HG2  sing N N 263 
PRO CG  HG3  sing N N 264 
PRO CD  HD2  sing N N 265 
PRO CD  HD3  sing N N 266 
PRO OXT HXT  sing N N 267 
SER N   CA   sing N N 268 
SER N   H    sing N N 269 
SER N   H2   sing N N 270 
SER CA  C    sing N N 271 
SER CA  CB   sing N N 272 
SER CA  HA   sing N N 273 
SER C   O    doub N N 274 
SER C   OXT  sing N N 275 
SER CB  OG   sing N N 276 
SER CB  HB2  sing N N 277 
SER CB  HB3  sing N N 278 
SER OG  HG   sing N N 279 
SER OXT HXT  sing N N 280 
THR N   CA   sing N N 281 
THR N   H    sing N N 282 
THR N   H2   sing N N 283 
THR CA  C    sing N N 284 
THR CA  CB   sing N N 285 
THR CA  HA   sing N N 286 
THR C   O    doub N N 287 
THR C   OXT  sing N N 288 
THR CB  OG1  sing N N 289 
THR CB  CG2  sing N N 290 
THR CB  HB   sing N N 291 
THR OG1 HG1  sing N N 292 
THR CG2 HG21 sing N N 293 
THR CG2 HG22 sing N N 294 
THR CG2 HG23 sing N N 295 
THR OXT HXT  sing N N 296 
TRP N   CA   sing N N 297 
TRP N   H    sing N N 298 
TRP N   H2   sing N N 299 
TRP CA  C    sing N N 300 
TRP CA  CB   sing N N 301 
TRP CA  HA   sing N N 302 
TRP C   O    doub N N 303 
TRP C   OXT  sing N N 304 
TRP CB  CG   sing N N 305 
TRP CB  HB2  sing N N 306 
TRP CB  HB3  sing N N 307 
TRP CG  CD1  doub Y N 308 
TRP CG  CD2  sing Y N 309 
TRP CD1 NE1  sing Y N 310 
TRP CD1 HD1  sing N N 311 
TRP CD2 CE2  doub Y N 312 
TRP CD2 CE3  sing Y N 313 
TRP NE1 CE2  sing Y N 314 
TRP NE1 HE1  sing N N 315 
TRP CE2 CZ2  sing Y N 316 
TRP CE3 CZ3  doub Y N 317 
TRP CE3 HE3  sing N N 318 
TRP CZ2 CH2  doub Y N 319 
TRP CZ2 HZ2  sing N N 320 
TRP CZ3 CH2  sing Y N 321 
TRP CZ3 HZ3  sing N N 322 
TRP CH2 HH2  sing N N 323 
TRP OXT HXT  sing N N 324 
TYR N   CA   sing N N 325 
TYR N   H    sing N N 326 
TYR N   H2   sing N N 327 
TYR CA  C    sing N N 328 
TYR CA  CB   sing N N 329 
TYR CA  HA   sing N N 330 
TYR C   O    doub N N 331 
TYR C   OXT  sing N N 332 
TYR CB  CG   sing N N 333 
TYR CB  HB2  sing N N 334 
TYR CB  HB3  sing N N 335 
TYR CG  CD1  doub Y N 336 
TYR CG  CD2  sing Y N 337 
TYR CD1 CE1  sing Y N 338 
TYR CD1 HD1  sing N N 339 
TYR CD2 CE2  doub Y N 340 
TYR CD2 HD2  sing N N 341 
TYR CE1 CZ   doub Y N 342 
TYR CE1 HE1  sing N N 343 
TYR CE2 CZ   sing Y N 344 
TYR CE2 HE2  sing N N 345 
TYR CZ  OH   sing N N 346 
TYR OH  HH   sing N N 347 
TYR OXT HXT  sing N N 348 
VAL N   CA   sing N N 349 
VAL N   H    sing N N 350 
VAL N   H2   sing N N 351 
VAL CA  C    sing N N 352 
VAL CA  CB   sing N N 353 
VAL CA  HA   sing N N 354 
VAL C   O    doub N N 355 
VAL C   OXT  sing N N 356 
VAL CB  CG1  sing N N 357 
VAL CB  CG2  sing N N 358 
VAL CB  HB   sing N N 359 
VAL CG1 HG11 sing N N 360 
VAL CG1 HG12 sing N N 361 
VAL CG1 HG13 sing N N 362 
VAL CG2 HG21 sing N N 363 
VAL CG2 HG22 sing N N 364 
VAL CG2 HG23 sing N N 365 
VAL OXT HXT  sing N N 366 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   3MF8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NGL 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016673 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009893 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006941 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . PRO A 1 1   ? -20.73066 -15.13797 -23.41673 1.000 14.07683 ? 1   PRO A N   1 
ATOM   2    C CA  . PRO A 1 1   ? -20.78346 -16.53322 -22.98321 1.000 10.24068 ? 1   PRO A CA  1 
ATOM   3    C C   . PRO A 1 1   ? -20.96235 -16.69576 -21.48623 1.000 11.09915 ? 1   PRO A C   1 
ATOM   4    O O   . PRO A 1 1   ? -20.70228 -15.78681 -20.67972 1.000 12.17285 ? 1   PRO A O   1 
ATOM   5    C CB  . PRO A 1 1   ? -19.40678 -17.08002 -23.37185 1.000 10.74183 ? 1   PRO A CB  1 
ATOM   6    C CG  . PRO A 1 1   ? -18.51178 -15.87656 -23.15379 1.000 12.38780 ? 1   PRO A CG  1 
ATOM   7    C CD  . PRO A 1 1   ? -19.33964 -14.71121 -23.67489 1.000 14.52381 ? 1   PRO A CD  1 
ATOM   8    N N   . VAL A 1 2   ? -21.42264 -17.88388 -21.11475 1.000 10.71585 ? 2   VAL A N   1 
ATOM   9    C CA  . VAL A 1 2   ? -21.34927 -18.34621 -19.73882 1.000 10.87656 ? 2   VAL A CA  1 
ATOM   10   C C   . VAL A 1 2   ? -20.55457 -19.63801 -19.76628 1.000 11.70386 ? 2   VAL A C   1 
ATOM   11   O O   . VAL A 1 2   ? -20.93335 -20.59574 -20.45086 1.000 11.74999 ? 2   VAL A O   1 
ATOM   12   C CB  . VAL A 1 2   ? -22.73611 -18.56066 -19.10233 1.000 12.06329 ? 2   VAL A CB  1 
ATOM   13   C CG1 . VAL A 1 2   ? -22.55253 -19.15299 -17.71385 1.000 13.55290 ? 2   VAL A CG1 1 
ATOM   14   C CG2 . VAL A 1 2   ? -23.50383 -17.24582 -19.00246 1.000 10.54384 ? 2   VAL A CG2 1 
ATOM   15   N N   . TYR A 1 3   ? -19.44213 -19.66342 -19.04955 1.000 10.16998 ? 3   TYR A N   1 
ATOM   16   C CA  . TYR A 1 3   ? -18.66923 -20.88774 -18.88398 1.000 11.73831 ? 3   TYR A CA  1 
ATOM   17   C C   . TYR A 1 3   ? -19.00358 -21.47139 -17.51724 1.000 11.81511 ? 3   TYR A C   1 
ATOM   18   O O   . TYR A 1 3   ? -18.63009 -20.90655 -16.48261 1.000 10.69841 ? 3   TYR A O   1 
ATOM   19   C CB  . TYR A 1 3   ? -17.17904 -20.60887 -19.02394 1.000 10.32789 ? 3   TYR A CB  1 
ATOM   20   C CG  . TYR A 1 3   ? -16.76122 -20.31994 -20.45265 1.000 11.27584 ? 3   TYR A CG  1 
ATOM   21   C CD1 . TYR A 1 3   ? -16.44526 -21.36204 -21.31758 1.000 13.32755 ? 3   TYR A CD1 1 
ATOM   22   C CD2 . TYR A 1 3   ? -16.64874 -19.01472 -20.92223 1.000 12.29907 ? 3   TYR A CD2 1 
ATOM   23   C CE1 . TYR A 1 3   ? -16.04012 -21.10716 -22.61697 1.000 14.02606 ? 3   TYR A CE1 1 
ATOM   24   C CE2 . TYR A 1 3   ? -16.25426 -18.75306 -22.22372 1.000 11.20793 ? 3   TYR A CE2 1 
ATOM   25   C CZ  . TYR A 1 3   ? -15.95349 -19.80826 -23.05755 1.000 12.50405 ? 3   TYR A CZ  1 
ATOM   26   O OH  . TYR A 1 3   ? -15.52856 -19.58678 -24.33552 1.000 14.45722 ? 3   TYR A OH  1 
ATOM   27   N N   . MET A 1 4   ? -19.73575 -22.58319 -17.50784 1.000 11.05710 ? 4   MET A N   1 
ATOM   28   C CA  . MET A 1 4   ? -19.97675 -23.30124 -16.26593 1.000 12.73015 ? 4   MET A CA  1 
ATOM   29   C C   . MET A 1 4   ? -18.77841 -24.21773 -16.04263 1.000 11.07749 ? 4   MET A C   1 
ATOM   30   O O   . MET A 1 4   ? -18.45154 -25.03709 -16.90404 1.000 13.16468 ? 4   MET A O   1 
ATOM   31   C CB  . MET A 1 4   ? -21.28228 -24.09790 -16.34555 1.000 12.29921 ? 4   MET A CB  1 
ATOM   32   C CG  . MET A 1 4   ? -22.42591 -23.20964 -16.81342 1.000 14.61912 ? 4   MET A CG  1 
ATOM   33   S SD  . MET A 1 4   ? -22.98093 -21.99066 -15.60764 1.000 15.22524 ? 4   MET A SD  1 
ATOM   34   C CE  . MET A 1 4   ? -23.16731 -23.02007 -14.13990 1.000 14.18175 ? 4   MET A CE  1 
ATOM   35   N N   . VAL A 1 5   ? -18.12400 -24.08981 -14.89570 1.000 12.17611 ? 5   VAL A N   1 
ATOM   36   C CA  . VAL A 1 5   ? -16.90541 -24.84202 -14.62618 1.000 10.94954 ? 5   VAL A CA  1 
ATOM   37   C C   . VAL A 1 5   ? -17.16414 -25.72780 -13.41978 1.000 12.02075 ? 5   VAL A C   1 
ATOM   38   O O   . VAL A 1 5   ? -17.33352 -25.22432 -12.30194 1.000 13.18622 ? 5   VAL A O   1 
ATOM   39   C CB  . VAL A 1 5   ? -15.70027 -23.92545 -14.38754 1.000 14.09996 ? 5   VAL A CB  1 
ATOM   40   C CG1 . VAL A 1 5   ? -14.46956 -24.77413 -14.11790 1.000 12.54349 ? 5   VAL A CG1 1 
ATOM   41   C CG2 . VAL A 1 5   ? -15.45347 -23.05359 -15.61388 1.000 11.05305 ? 5   VAL A CG2 1 
ATOM   42   N N   . TYR A 1 6   ? -17.19177 -27.04183 -13.64065 1.000 12.56776 ? 6   TYR A N   1 
ATOM   43   C CA  . TYR A 1 6   ? -17.54048 -28.01577 -12.60901 1.000 10.27357 ? 6   TYR A CA  1 
ATOM   44   C C   . TYR A 1 6   ? -16.27108 -28.61604 -12.01810 1.000 13.64458 ? 6   TYR A C   1 
ATOM   45   O O   . TYR A 1 6   ? -15.51045 -29.29184 -12.72487 1.000 13.79206 ? 6   TYR A O   1 
ATOM   46   C CB  . TYR A 1 6   ? -18.42439 -29.11159 -13.18846 1.000 12.89698 ? 6   TYR A CB  1 
ATOM   47   C CG  . TYR A 1 6   ? -19.68556 -28.54522 -13.74121 1.000 11.40620 ? 6   TYR A CG  1 
ATOM   48   C CD1 . TYR A 1 6   ? -20.79122 -28.34247 -12.91634 1.000 11.46655 ? 6   TYR A CD1 1 
ATOM   49   C CD2 . TYR A 1 6   ? -19.76186 -28.15408 -15.06731 1.000 10.60047 ? 6   TYR A CD2 1 
ATOM   50   C CE1 . TYR A 1 6   ? -21.97564 -27.81921 -13.42240 1.000 13.82005 ? 6   TYR A CE1 1 
ATOM   51   C CE2 . TYR A 1 6   ? -20.92877 -27.60292 -15.58285 1.000 10.06458 ? 6   TYR A CE2 1 
ATOM   52   C CZ  . TYR A 1 6   ? -22.02984 -27.44314 -14.74753 1.000 14.59070 ? 6   TYR A CZ  1 
ATOM   53   O OH  . TYR A 1 6   ? -23.19142 -26.90365 -15.22596 1.000 12.46780 ? 6   TYR A OH  1 
ATOM   54   N N   . VAL A 1 7   ? -16.05148 -28.36480 -10.72348 1.000 12.47557 ? 7   VAL A N   1 
ATOM   55   C CA  . VAL A 1 7   ? -14.83830 -28.75283 -10.01124 1.000 11.55618 ? 7   VAL A CA  1 
ATOM   56   C C   . VAL A 1 7   ? -15.21248 -29.31713 -8.64959  1.000 12.26663 ? 7   VAL A C   1 
ATOM   57   O O   . VAL A 1 7   ? -16.27756 -29.03151 -8.09931  1.000 14.39961 ? 7   VAL A O   1 
ATOM   58   C CB  . VAL A 1 7   ? -13.85148 -27.57080 -9.81838  1.000 15.14054 ? 7   VAL A CB  1 
ATOM   59   C CG1 . VAL A 1 7   ? -13.18264 -27.20648 -11.13479 1.000 17.43925 ? 7   VAL A CG1 1 
ATOM   60   C CG2 . VAL A 1 7   ? -14.58176 -26.35498 -9.24109  1.000 15.05851 ? 7   VAL A CG2 1 
ATOM   61   N N   . SER A 1 8   ? -14.30017 -30.10533 -8.08814  1.000 14.58667 ? 8   SER A N   1 
ATOM   62   C CA  . SER A 1 8   ? -14.49804 -30.57541 -6.72661  1.000 15.52398 ? 8   SER A CA  1 
ATOM   63   C C   . SER A 1 8   ? -14.25343 -29.44398 -5.73651  1.000 16.84740 ? 8   SER A C   1 
ATOM   64   O O   . SER A 1 8   ? -13.41040 -28.57393 -5.95790  1.000 12.46074 ? 8   SER A O   1 
ATOM   65   C CB  . SER A 1 8   ? -13.57876 -31.75735 -6.40887  1.000 19.06543 ? 8   SER A CB  1 
ATOM   66   O OG  . SER A 1 8   ? -13.89777 -32.88365 -7.20890  1.000 22.52184 ? 8   SER A OG  1 
ATOM   67   N N   . GLN A 1 9   ? -15.03440 -29.45488 -4.65563  1.000 17.69262 ? 9   GLN A N   1 
ATOM   68   C CA  . GLN A 1 9   ? -14.83076 -28.55343 -3.52801  1.000 16.16502 ? 9   GLN A CA  1 
ATOM   69   C C   . GLN A 1 9   ? -13.36600 -28.52631 -3.10130  1.000 19.05319 ? 9   GLN A C   1 
ATOM   70   O O   . GLN A 1 9   ? -12.71003 -29.56666 -3.01794  1.000 19.24329 ? 9   GLN A O   1 
ATOM   71   C CB  . GLN A 1 9   ? -15.71913 -29.00984 -2.36575  1.000 18.57762 ? 9   GLN A CB  1 
ATOM   72   C CG  . GLN A 1 9   ? -15.77025 -28.03756 -1.19621  1.000 22.67839 ? 9   GLN A CG  1 
ATOM   73   C CD  . GLN A 1 9   ? -16.23181 -26.66783 -1.61590  1.000 31.22746 ? 9   GLN A CD  1 
ATOM   74   O OE1 . GLN A 1 9   ? -17.29381 -26.52174 -2.22616  1.000 33.38774 ? 9   GLN A OE1 1 
ATOM   75   N NE2 . GLN A 1 9   ? -15.41992 -25.65008 -1.32670  1.000 31.33294 ? 9   GLN A NE2 1 
ATOM   76   N N   . ASP A 1 10  ? -12.85624 -27.31440 -2.83461  1.000 17.54987 ? 10  ASP A N   1 
ATOM   77   C CA  . ASP A 1 10  ? -11.48043 -27.05759 -2.39712  1.000 20.93052 ? 10  ASP A CA  1 
ATOM   78   C C   . ASP A 1 10  ? -10.38615 -27.32790 -3.42621  1.000 20.40268 ? 10  ASP A C   1 
ATOM   79   O O   . ASP A 1 10  ? -9.21455  -27.04066 -3.14921  1.000 21.00668 ? 10  ASP A O   1 
ATOM   80   C CB  . ASP A 1 10  ? -11.12032 -27.85347 -1.13553  1.000 21.13430 ? 10  ASP A CB  1 
ATOM   81   C CG  . ASP A 1 10  ? -11.92771 -27.44121 0.08284   1.000 24.65949 ? 10  ASP A CG  1 
ATOM   82   O OD1 . ASP A 1 10  ? -12.84562 -26.61427 -0.03973  1.000 25.85838 ? 10  ASP A OD1 1 
ATOM   83   O OD2 . ASP A 1 10  ? -11.60562 -27.92909 1.18055   1.000 29.67727 ? 10  ASP A OD2 1 
ATOM   84   N N   . ARG A 1 11  ? -10.71014 -27.87277 -4.60331  1.000 18.31994 ? 11  ARG A N   1 
ATOM   85   C CA  . ARG A 1 11  ? -9.64429  -28.07454 -5.58310  1.000 15.96034 ? 11  ARG A CA  1 
ATOM   86   C C   . ARG A 1 11  ? -9.06411  -26.73949 -6.06081  1.000 17.14599 ? 11  ARG A C   1 
ATOM   87   O O   . ARG A 1 11  ? -7.86503  -26.64865 -6.33379  1.000 20.08237 ? 11  ARG A O   1 
ATOM   88   C CB  . ARG A 1 11  ? -10.14959 -28.90611 -6.76663  1.000 19.38969 ? 11  ARG A CB  1 
ATOM   89   C CG  . ARG A 1 11  ? -9.13773  -29.01470 -7.91638  1.000 18.27884 ? 11  ARG A CG  1 
ATOM   90   C CD  . ARG A 1 11  ? -7.86484  -29.72741 -7.43816  1.000 20.11440 ? 11  ARG A CD  1 
ATOM   91   N NE  . ARG A 1 11  ? -6.95654  -30.00269 -8.53937  1.000 19.78570 ? 11  ARG A NE  1 
ATOM   92   C CZ  . ARG A 1 11  ? -6.12626  -29.10875 -9.06656  1.000 29.12511 ? 11  ARG A CZ  1 
ATOM   93   N NH1 . ARG A 1 11  ? -6.12680  -27.84210 -8.67392  1.000 23.88663 ? 11  ARG A NH1 1 
ATOM   94   N NH2 . ARG A 1 11  ? -5.30131  -29.48434 -10.04094 1.000 26.05291 ? 11  ARG A NH2 1 
ATOM   95   N N   . LEU A 1 12  ? -9.87982  -25.69038 -6.14574  1.000 18.63214 ? 12  LEU A N   1 
ATOM   96   C CA  . LEU A 1 12  ? -9.40861  -24.36749 -6.55648  1.000 17.80316 ? 12  LEU A CA  1 
ATOM   97   C C   . LEU A 1 12  ? -9.60713  -23.38452 -5.41154  1.000 15.36687 ? 12  LEU A C   1 
ATOM   98   O O   . LEU A 1 12  ? -10.73644 -23.19308 -4.94488  1.000 19.24128 ? 12  LEU A O   1 
ATOM   99   C CB  . LEU A 1 12  ? -10.16118 -23.87505 -7.79694  1.000 18.60606 ? 12  LEU A CB  1 
ATOM   100  C CG  . LEU A 1 12  ? -10.06333 -24.74628 -9.04458  1.000 15.43205 ? 12  LEU A CG  1 
ATOM   101  C CD1 . LEU A 1 12  ? -10.92286 -24.17289 -10.16724 1.000 15.33337 ? 12  LEU A CD1 1 
ATOM   102  C CD2 . LEU A 1 12  ? -8.61827  -24.86664 -9.50062  1.000 19.89821 ? 12  LEU A CD2 1 
ATOM   103  N N   . THR A 1 13  ? -8.51575  -22.75817 -4.96380  1.000 18.63655 ? 13  THR A N   1 
ATOM   104  C CA  . THR A 1 13  ? -8.59387  -21.66287 -4.01266  1.000 18.79229 ? 13  THR A CA  1 
ATOM   105  C C   . THR A 1 13  ? -9.25297  -20.46672 -4.67773  1.000 23.18482 ? 13  THR A C   1 
ATOM   106  O O   . THR A 1 13  ? -9.44362  -20.45319 -5.89865  1.000 21.09634 ? 13  THR A O   1 
ATOM   107  C CB  . THR A 1 13  ? -7.20533  -21.23355 -3.54587  1.000 18.11880 ? 13  THR A CB  1 
ATOM   108  O OG1 . THR A 1 13  ? -6.37471  -21.00966 -4.68916  1.000 20.05300 ? 13  THR A OG1 1 
ATOM   109  C CG2 . THR A 1 13  ? -6.59271  -22.30894 -2.67937  1.000 21.33458 ? 13  THR A CG2 1 
ATOM   110  N N   . PRO A 1 14  ? -9.60065  -19.43344 -3.90007  1.000 24.88519 ? 14  PRO A N   1 
ATOM   111  C CA  . PRO A 1 14  ? -10.04405 -18.17729 -4.52603  1.000 20.00423 ? 14  PRO A CA  1 
ATOM   112  C C   . PRO A 1 14  ? -9.06186  -17.66010 -5.55933  1.000 19.13623 ? 14  PRO A C   1 
ATOM   113  O O   . PRO A 1 14  ? -9.46955  -17.19569 -6.63164  1.000 18.96569 ? 14  PRO A O   1 
ATOM   114  C CB  . PRO A 1 14  ? -10.16692 -17.22969 -3.32608  1.000 24.28206 ? 14  PRO A CB  1 
ATOM   115  C CG  . PRO A 1 14  ? -10.55057 -18.12711 -2.20781  1.000 24.45342 ? 14  PRO A CG  1 
ATOM   116  C CD  . PRO A 1 14  ? -9.88224  -19.44870 -2.44854  1.000 21.99095 ? 14  PRO A CD  1 
ATOM   117  N N   . SER A 1 15  ? -7.76153  -17.75820 -5.27215  1.000 23.44170 ? 15  SER A N   1 
ATOM   118  C CA  . SER A 1 15  ? -6.75814  -17.27475 -6.21180  1.000 17.94599 ? 15  SER A CA  1 
ATOM   119  C C   . SER A 1 15  ? -6.70963  -18.14274 -7.46540  1.000 20.10188 ? 15  SER A C   1 
ATOM   120  O O   . SER A 1 15  ? -6.53325  -17.62953 -8.57943  1.000 19.76957 ? 15  SER A O   1 
ATOM   121  C CB  . SER A 1 15  ? -5.38783  -17.23348 -5.53605  1.000 22.92063 ? 15  SER A CB  1 
ATOM   122  O OG  . SER A 1 15  ? -4.40569  -16.80782 -6.46021  1.000 29.28245 ? 15  SER A OG  1 
ATOM   123  N N   . ALA A 1 16  ? -6.84775  -19.45922 -7.30589  1.000 16.29460 ? 16  ALA A N   1 
ATOM   124  C CA  . ALA A 1 16  ? -6.84739  -20.31897 -8.47998  1.000 20.61569 ? 16  ALA A CA  1 
ATOM   125  C C   . ALA A 1 16  ? -8.13235  -20.14950 -9.28342  1.000 18.48614 ? 16  ALA A C   1 
ATOM   126  O O   . ALA A 1 16  ? -8.10722  -20.25748 -10.51353 1.000 16.63790 ? 16  ALA A O   1 
ATOM   127  C CB  . ALA A 1 16  ? -6.63848  -21.78005 -8.07333  1.000 18.18161 ? 16  ALA A CB  1 
ATOM   128  N N   . LYS A 1 17  ? -9.25829  -19.87677 -8.61964  1.000 16.77712 ? 17  LYS A N   1 
ATOM   129  C CA  . LYS A 1 17  ? -10.48086 -19.60344 -9.37822  1.000 18.73226 ? 17  LYS A CA  1 
ATOM   130  C C   . LYS A 1 17  ? -10.32949 -18.33456 -10.19680 1.000 20.57600 ? 17  LYS A C   1 
ATOM   131  O O   . LYS A 1 17  ? -10.74012 -18.28593 -11.36308 1.000 15.91556 ? 17  LYS A O   1 
ATOM   132  C CB  . LYS A 1 17  ? -11.69130 -19.48626 -8.45524  1.000 15.24863 ? 17  LYS A CB  1 
ATOM   133  C CG  . LYS A 1 17  ? -12.14737 -20.79159 -7.84781  1.000 15.76031 ? 17  LYS A CG  1 
ATOM   134  C CD  . LYS A 1 17  ? -13.37902 -20.56158 -6.99270  1.000 17.21012 ? 17  LYS A CD  1 
ATOM   135  C CE  . LYS A 1 17  ? -13.71164 -21.79802 -6.16611  1.000 23.72854 ? 17  LYS A CE  1 
ATOM   136  N NZ  . LYS A 1 17  ? -14.24944 -21.44449 -4.83105  1.000 31.63577 ? 17  LYS A NZ  1 
ATOM   137  N N   . HIS A 1 18  ? -9.73615  -17.29633 -9.60725  1.000 16.23544 ? 18  HIS A N   1 
ATOM   138  C CA  . HIS A 1 18  ? -9.46705  -16.09289 -10.38395 1.000 17.49067 ? 18  HIS A CA  1 
ATOM   139  C C   . HIS A 1 18  ? -8.56296  -16.38982 -11.56559 1.000 17.67718 ? 18  HIS A C   1 
ATOM   140  O O   . HIS A 1 18  ? -8.80053  -15.89271 -12.67009 1.000 17.46170 ? 18  HIS A O   1 
ATOM   141  C CB  . HIS A 1 18  ? -8.86227  -14.98847 -9.51298  1.000 16.09392 ? 18  HIS A CB  1 
ATOM   142  C CG  . HIS A 1 18  ? -8.39727  -13.80242 -10.30902 1.000 28.36646 ? 18  HIS A CG  1 
ATOM   143  N ND1 . HIS A 1 18  ? -7.12223  -13.70753 -10.82929 1.000 33.38212 ? 18  HIS A ND1 1 
ATOM   144  C CD2 . HIS A 1 18  ? -9.05616  -12.69220 -10.72580 1.000 31.71912 ? 18  HIS A CD2 1 
ATOM   145  C CE1 . HIS A 1 18  ? -7.00757  -12.57618 -11.50470 1.000 30.34555 ? 18  HIS A CE1 1 
ATOM   146  N NE2 . HIS A 1 18  ? -8.16791  -11.94444 -11.46011 1.000 31.70537 ? 18  HIS A NE2 1 
ATOM   147  N N   . ALA A 1 19  ? -7.51965  -17.19635 -11.36253 1.000 15.93888 ? 19  ALA A N   1 
ATOM   148  C CA  . ALA A 1 19  ? -6.62680  -17.50634 -12.47117 1.000 15.91053 ? 19  ALA A CA  1 
ATOM   149  C C   . ALA A 1 19  ? -7.35620  -18.27686 -13.56204 1.000 16.99422 ? 19  ALA A C   1 
ATOM   150  O O   . ALA A 1 19  ? -7.15957  -18.01292 -14.75393 1.000 17.18214 ? 19  ALA A O   1 
ATOM   151  C CB  . ALA A 1 19  ? -5.41719  -18.29855 -11.97997 1.000 18.14395 ? 19  ALA A CB  1 
ATOM   152  N N   . VAL A 1 20  ? -8.18287  -19.25448 -13.17788 1.000 15.13980 ? 20  VAL A N   1 
ATOM   153  C CA  . VAL A 1 20  ? -8.87458  -20.04296 -14.19574 1.000 13.32843 ? 20  VAL A CA  1 
ATOM   154  C C   . VAL A 1 20  ? -9.87661  -19.16917 -14.93939 1.000 13.32619 ? 20  VAL A C   1 
ATOM   155  O O   . VAL A 1 20  ? -9.96697  -19.21808 -16.17252 1.000 15.55783 ? 20  VAL A O   1 
ATOM   156  C CB  . VAL A 1 20  ? -9.54898  -21.27488 -13.56999 1.000 18.11154 ? 20  VAL A CB  1 
ATOM   157  C CG1 . VAL A 1 20  ? -10.53565 -21.90821 -14.56061 1.000 12.82596 ? 20  VAL A CG1 1 
ATOM   158  C CG2 . VAL A 1 20  ? -8.49672  -22.29610 -13.13475 1.000 14.85771 ? 20  VAL A CG2 1 
ATOM   159  N N   . ALA A 1 21  ? -10.62494 -18.34250 -14.20887 1.000 13.26223 ? 21  ALA A N   1 
ATOM   160  C CA  . ALA A 1 21  ? -11.57853 -17.44232 -14.85552 1.000 12.72584 ? 21  ALA A CA  1 
ATOM   161  C C   . ALA A 1 21  ? -10.86988 -16.46188 -15.78303 1.000 19.64039 ? 21  ALA A C   1 
ATOM   162  O O   . ALA A 1 21  ? -11.34532 -16.18459 -16.89215 1.000 13.55668 ? 21  ALA A O   1 
ATOM   163  C CB  . ALA A 1 21  ? -12.38710 -16.68971 -13.80112 1.000 17.65673 ? 21  ALA A CB  1 
ATOM   164  N N   . LYS A 1 22  ? -9.72119  -15.92914 -15.35072 1.000 14.34412 ? 22  LYS A N   1 
ATOM   165  C CA  . LYS A 1 22  ? -8.97072  -15.02698 -16.21671 1.000 17.14637 ? 22  LYS A CA  1 
ATOM   166  C C   . LYS A 1 22  ? -8.48272  -15.73865 -17.47435 1.000 16.44845 ? 22  LYS A C   1 
ATOM   167  O O   . LYS A 1 22  ? -8.53811  -15.17017 -18.57161 1.000 19.99929 ? 22  LYS A O   1 
ATOM   168  C CB  . LYS A 1 22  ? -7.78874  -14.41609 -15.45375 1.000 20.75729 ? 22  LYS A CB  1 
ATOM   169  C CG  . LYS A 1 22  ? -6.90805  -13.52010 -16.34085 1.000 27.23859 ? 22  LYS A CG  1 
ATOM   170  C CD  . LYS A 1 22  ? -5.60446  -13.11898 -15.64727 1.000 26.66754 ? 22  LYS A CD  1 
ATOM   171  C CE  . LYS A 1 22  ? -4.52758  -12.80919 -16.67041 1.000 33.97608 ? 22  LYS A CE  1 
ATOM   172  N NZ  . LYS A 1 22  ? -4.92559  -11.63857 -17.51021 1.000 35.11687 ? 22  LYS A NZ  1 
ATOM   173  N N   . ALA A 1 23  ? -7.99788  -16.98242 -17.34081 1.000 16.73111 ? 23  ALA A N   1 
ATOM   174  C CA  . ALA A 1 23  ? -7.53085  -17.73408 -18.50640 1.000 18.31402 ? 23  ALA A CA  1 
ATOM   175  C C   . ALA A 1 23  ? -8.64847  -17.94471 -19.51965 1.000 17.07341 ? 23  ALA A C   1 
ATOM   176  O O   . ALA A 1 23  ? -8.45480  -17.77777 -20.73153 1.000 16.71258 ? 23  ALA A O   1 
ATOM   177  C CB  . ALA A 1 23  ? -6.96675  -19.08785 -18.08698 1.000 22.51839 ? 23  ALA A CB  1 
ATOM   178  N N   . ILE A 1 24  ? -9.81564  -18.35760 -19.04210 1.000 16.55094 ? 24  ILE A N   1 
ATOM   179  C CA  . ILE A 1 24  ? -10.93959 -18.57751 -19.94758 1.000 14.05447 ? 24  ILE A CA  1 
ATOM   180  C C   . ILE A 1 24  ? -11.38905 -17.26967 -20.57461 1.000 13.72518 ? 24  ILE A C   1 
ATOM   181  O O   . ILE A 1 24  ? -11.69284 -17.20443 -21.77539 1.000 12.67110 ? 24  ILE A O   1 
ATOM   182  C CB  . ILE A 1 24  ? -12.08645 -19.25790 -19.18997 1.000 14.59484 ? 24  ILE A CB  1 
ATOM   183  C CG1 . ILE A 1 24  ? -11.67406 -20.67741 -18.79958 1.000 12.17701 ? 24  ILE A CG1 1 
ATOM   184  C CG2 . ILE A 1 24  ? -13.35070 -19.23372 -20.04841 1.000 11.56556 ? 24  ILE A CG2 1 
ATOM   185  C CD1 . ILE A 1 24  ? -12.67369 -21.37701 -17.87811 1.000 13.11745 ? 24  ILE A CD1 1 
ATOM   186  N N   . THR A 1 25  ? -11.48514 -16.21848 -19.76265 1.000 12.80891 ? 25  THR A N   1 
ATOM   187  C CA  . THR A 1 25  ? -11.96876 -14.93606 -20.25735 1.000 14.75123 ? 25  THR A CA  1 
ATOM   188  C C   . THR A 1 25  ? -11.00901 -14.33914 -21.28050 1.000 15.17397 ? 25  THR A C   1 
ATOM   189  O O   . THR A 1 25  ? -11.44011 -13.83195 -22.32302 1.000 15.45253 ? 25  THR A O   1 
ATOM   190  C CB  . THR A 1 25  ? -12.17101 -13.98618 -19.08404 1.000 15.24193 ? 25  THR A CB  1 
ATOM   191  O OG1 . THR A 1 25  ? -13.11732 -14.55590 -18.17282 1.000 15.29761 ? 25  THR A OG1 1 
ATOM   192  C CG2 . THR A 1 25  ? -12.66761 -12.62001 -19.56655 1.000 15.86348 ? 25  THR A CG2 1 
ATOM   193  N N   . ASP A 1 26  ? -9.70221  -14.40416 -21.00670 1.000 16.69337 ? 26  ASP A N   1 
ATOM   194  C CA  . ASP A 1 26  ? -8.71638  -13.91922 -21.97285 1.000 17.45035 ? 26  ASP A CA  1 
ATOM   195  C C   . ASP A 1 26  ? -8.77059  -14.72443 -23.26634 1.000 15.99371 ? 26  ASP A C   1 
ATOM   196  O O   . ASP A 1 26  ? -8.64063  -14.17151 -24.36720 1.000 16.42887 ? 26  ASP A O   1 
ATOM   197  C CB  . ASP A 1 26  ? -7.30670  -13.98001 -21.36867 1.000 18.71177 ? 26  ASP A CB  1 
ATOM   198  C CG  . ASP A 1 26  ? -7.07747  -12.92875 -20.28557 1.000 25.23974 ? 26  ASP A CG  1 
ATOM   199  O OD1 . ASP A 1 26  ? -7.95763  -12.06953 -20.07629 1.000 23.92808 ? 26  ASP A OD1 1 
ATOM   200  O OD2 . ASP A 1 26  ? -6.00218  -12.95884 -19.64512 1.000 26.84506 ? 26  ASP A OD2 1 
ATOM   201  N N   . ALA A 1 27  ? -8.96340  -16.03661 -23.15670 1.000 14.50468 ? 27  ALA A N   1 
ATOM   202  C CA  . ALA A 1 27  ? -9.06371  -16.86698 -24.34858 1.000 14.36309 ? 27  ALA A CA  1 
ATOM   203  C C   . ALA A 1 27  ? -10.25563 -16.44494 -25.18992 1.000 14.55185 ? 27  ALA A C   1 
ATOM   204  O O   . ALA A 1 27  ? -10.15551 -16.29189 -26.41540 1.000 15.12673 ? 27  ALA A O   1 
ATOM   205  C CB  . ALA A 1 27  ? -9.18482  -18.33827 -23.95169 1.000 16.91595 ? 27  ALA A CB  1 
ATOM   206  N N   . HIS A 1 28  ? -11.39664 -16.23486 -24.53481 1.000 14.09399 ? 28  HIS A N   1 
ATOM   207  C CA  . HIS A 1 28  ? -12.61265 -15.89469 -25.26328 1.000 15.19391 ? 28  HIS A CA  1 
ATOM   208  C C   . HIS A 1 28  ? -12.48956 -14.53960 -25.95105 1.000 15.94892 ? 28  HIS A C   1 
ATOM   209  O O   . HIS A 1 28  ? -12.82234 -14.40888 -27.13993 1.000 18.60242 ? 28  HIS A O   1 
ATOM   210  C CB  . HIS A 1 28  ? -13.81195 -15.93807 -24.31623 1.000 15.31137 ? 28  HIS A CB  1 
ATOM   211  C CG  . HIS A 1 28  ? -15.12152 -15.97429 -25.03526 1.000 15.65365 ? 28  HIS A CG  1 
ATOM   212  N ND1 . HIS A 1 28  ? -15.72096 -17.15816 -25.40821 1.000 13.29255 ? 28  HIS A ND1 1 
ATOM   213  C CD2 . HIS A 1 28  ? -15.92111 -14.98216 -25.49298 1.000 16.83831 ? 28  HIS A CD2 1 
ATOM   214  C CE1 . HIS A 1 28  ? -16.83714 -16.89246 -26.06511 1.000 16.32131 ? 28  HIS A CE1 1 
ATOM   215  N NE2 . HIS A 1 28  ? -16.98310 -15.58117 -26.12841 1.000 15.37272 ? 28  HIS A NE2 1 
ATOM   216  N N   . ARG A 1 29  ? -12.02137 -13.51145 -25.22954 1.000 14.41809 ? 29  ARG A N   1 
ATOM   217  C CA  . ARG A 1 29  ? -11.81914 -12.21027 -25.87125 1.000 17.25031 ? 29  ARG A CA  1 
ATOM   218  C C   . ARG A 1 29  ? -10.77805 -12.30889 -26.97312 1.000 15.37016 ? 29  ARG A C   1 
ATOM   219  O O   . ARG A 1 29  ? -10.95344 -11.73598 -28.05541 1.000 20.37628 ? 29  ARG A O   1 
ATOM   220  C CB  . ARG A 1 29  ? -11.39120 -11.13293 -24.86262 1.000 20.09540 ? 29  ARG A CB  1 
ATOM   221  C CG  . ARG A 1 29  ? -10.95178 -9.81285  -25.59648 1.000 25.86248 ? 29  ARG A CG  1 
ATOM   222  C CD  . ARG A 1 29  ? -10.88342 -8.57438  -24.69609 1.000 37.07093 ? 29  ARG A CD  1 
ATOM   223  N NE  . ARG A 1 29  ? -11.26838 -7.31567  -25.33926 1.000 41.87787 ? 29  ARG A NE  1 
ATOM   224  C CZ  . ARG A 1 29  ? -11.86131 -6.29137  -24.72392 1.000 38.77527 ? 29  ARG A CZ  1 
ATOM   225  N NH1 . ARG A 1 29  ? -12.14551 -6.32249  -23.42937 1.000 27.01425 ? 29  ARG A NH1 1 
ATOM   226  N NH2 . ARG A 1 29  ? -12.16690 -5.19936  -25.42333 1.000 40.21717 ? 29  ARG A NH2 1 
ATOM   227  N N   . GLY A 1 30  ? -9.68401  -13.03358 -26.71906 1.000 17.74700 ? 30  GLY A N   1 
ATOM   228  C CA  . GLY A 1 30  ? -8.59317  -13.07916 -27.68367 1.000 14.68014 ? 30  GLY A CA  1 
ATOM   229  C C   . GLY A 1 30  ? -8.99150  -13.67613 -29.02166 1.000 21.76044 ? 30  GLY A C   1 
ATOM   230  O O   . GLY A 1 30  ? -8.59197  -13.17847 -30.08271 1.000 20.99163 ? 30  GLY A O   1 
ATOM   231  N N   . LEU A 1 31  ? -9.79884  -14.73329 -28.99807 1.000 16.01694 ? 31  LEU A N   1 
ATOM   232  C CA  . LEU A 1 31  ? -10.16189 -15.41694 -30.22377 1.000 17.12382 ? 31  LEU A CA  1 
ATOM   233  C C   . LEU A 1 31  ? -11.48728 -14.94446 -30.82919 1.000 18.22307 ? 31  LEU A C   1 
ATOM   234  O O   . LEU A 1 31  ? -11.68744 -15.13952 -32.03103 1.000 18.64076 ? 31  LEU A O   1 
ATOM   235  C CB  . LEU A 1 31  ? -10.21527 -16.93168 -29.97643 1.000 22.46160 ? 31  LEU A CB  1 
ATOM   236  C CG  . LEU A 1 31  ? -8.83757  -17.59337 -29.83938 1.000 20.52275 ? 31  LEU A CG  1 
ATOM   237  C CD1 . LEU A 1 31  ? -8.94822  -18.94073 -29.19516 1.000 18.56935 ? 31  LEU A CD1 1 
ATOM   238  C CD2 . LEU A 1 31  ? -8.17999  -17.72824 -31.21223 1.000 23.95306 ? 31  LEU A CD2 1 
ATOM   239  N N   . THR A 1 32  ? -12.39999 -14.34605 -30.04417 1.000 17.88041 ? 32  THR A N   1 
ATOM   240  C CA  . THR A 1 32  ? -13.69546 -13.91168 -30.57042 1.000 18.75187 ? 32  THR A CA  1 
ATOM   241  C C   . THR A 1 32  ? -13.85228 -12.40152 -30.67911 1.000 16.84083 ? 32  THR A C   1 
ATOM   242  O O   . THR A 1 32  ? -14.75405 -11.94123 -31.38675 1.000 19.17676 ? 32  THR A O   1 
ATOM   243  C CB  . THR A 1 32  ? -14.86093 -14.41479 -29.70145 1.000 16.65604 ? 32  THR A CB  1 
ATOM   244  O OG1 . THR A 1 32  ? -14.93398 -13.63058 -28.50112 1.000 14.84090 ? 32  THR A OG1 1 
ATOM   245  C CG2 . THR A 1 32  ? -14.71530 -15.89764 -29.35111 1.000 16.76886 ? 32  THR A CG2 1 
ATOM   246  N N   . GLY A 1 33  ? -13.02185 -11.62004 -29.99145 1.000 18.67774 ? 33  GLY A N   1 
ATOM   247  C CA  . GLY A 1 33  ? -13.19956 -10.18723 -29.95063 1.000 18.24554 ? 33  GLY A CA  1 
ATOM   248  C C   . GLY A 1 33  ? -14.25625 -9.70229  -28.98763 1.000 17.65471 ? 33  GLY A C   1 
ATOM   249  O O   . GLY A 1 33  ? -14.38722 -8.48983  -28.79782 1.000 19.93355 ? 33  GLY A O   1 
ATOM   250  N N   . THR A 1 34  ? -15.00878 -10.59833 -28.35879 1.000 17.96953 ? 34  THR A N   1 
ATOM   251  C CA  . THR A 1 34  ? -15.99793 -10.18099 -27.36914 1.000 15.65427 ? 34  THR A CA  1 
ATOM   252  C C   . THR A 1 34  ? -15.30970 -9.57368  -26.15083 1.000 22.22547 ? 34  THR A C   1 
ATOM   253  O O   . THR A 1 34  ? -14.35421 -10.14938 -25.62178 1.000 20.12641 ? 34  THR A O   1 
ATOM   254  C CB  . THR A 1 34  ? -16.84408 -11.38608 -26.95877 1.000 17.42449 ? 34  THR A CB  1 
ATOM   255  O OG1 . THR A 1 34  ? -17.53049 -11.89285 -28.10731 1.000 19.22147 ? 34  THR A OG1 1 
ATOM   256  C CG2 . THR A 1 34  ? -17.84916 -11.02440 -25.88036 1.000 20.03936 ? 34  THR A CG2 1 
ATOM   257  N N   . GLN A 1 35  ? -15.80652 -8.41826  -25.69793 1.000 18.48051 ? 35  GLN A N   1 
ATOM   258  C CA  . GLN A 1 35  ? -15.20683 -7.70643  -24.57177 1.000 20.20500 ? 35  GLN A CA  1 
ATOM   259  C C   . GLN A 1 35  ? -15.12994 -8.60314  -23.34302 1.000 18.66526 ? 35  GLN A C   1 
ATOM   260  O O   . GLN A 1 35  ? -15.99827 -9.44380  -23.11783 1.000 14.63066 ? 35  GLN A O   1 
ATOM   261  C CB  . GLN A 1 35  ? -16.02258 -6.45844  -24.22506 1.000 17.00271 ? 35  GLN A CB  1 
ATOM   262  C CG  . GLN A 1 35  ? -16.13179 -5.42582  -25.34145 1.000 20.77686 ? 35  GLN A CG  1 
ATOM   263  C CD  . GLN A 1 35  ? -17.44688 -5.55380  -26.10531 1.000 20.41396 ? 35  GLN A CD  1 
ATOM   264  O OE1 . GLN A 1 35  ? -17.91311 -6.66249  -26.34774 1.000 18.57248 ? 35  GLN A OE1 1 
ATOM   265  N NE2 . GLN A 1 35  ? -18.05827 -4.41670  -26.46447 1.000 21.03302 ? 35  GLN A NE2 1 
ATOM   266  N N   . HIS A 1 36  ? -14.07868 -8.40069  -22.53659 1.000 17.40950 ? 36  HIS A N   1 
ATOM   267  C CA  . HIS A 1 36  ? -13.89103 -9.18771  -21.31647 1.000 20.05711 ? 36  HIS A CA  1 
ATOM   268  C C   . HIS A 1 36  ? -15.15482 -9.22034  -20.47712 1.000 14.41738 ? 36  HIS A C   1 
ATOM   269  O O   . HIS A 1 36  ? -15.55117 -10.27516 -19.97534 1.000 15.59522 ? 36  HIS A O   1 
ATOM   270  C CB  . HIS A 1 36  ? -12.75383 -8.61922  -20.45847 1.000 17.08867 ? 36  HIS A CB  1 
ATOM   271  C CG  . HIS A 1 36  ? -11.38100 -8.88294  -20.99543 1.000 25.51001 ? 36  HIS A CG  1 
ATOM   272  N ND1 . HIS A 1 36  ? -10.73427 -10.08946 -20.83402 1.000 30.16272 ? 36  HIS A ND1 1 
ATOM   273  C CD2 . HIS A 1 36  ? -10.49687 -8.06436  -21.61118 1.000 27.99729 ? 36  HIS A CD2 1 
ATOM   274  C CE1 . HIS A 1 36  ? -9.53080  -10.01923 -21.37518 1.000 27.67789 ? 36  HIS A CE1 1 
ATOM   275  N NE2 . HIS A 1 36  ? -9.36339  -8.80246  -21.85918 1.000 30.35232 ? 36  HIS A NE2 1 
ATOM   276  N N   . PHE A 1 37  ? -15.79497 -8.05981  -20.29420 1.000 18.13403 ? 37  PHE A N   1 
ATOM   277  C CA  . PHE A 1 37  ? -16.91430 -7.98985  -19.36610 1.000 13.75053 ? 37  PHE A CA  1 
ATOM   278  C C   . PHE A 1 37  ? -18.13713 -8.76406  -19.84066 1.000 15.83528 ? 37  PHE A C   1 
ATOM   279  O O   . PHE A 1 37  ? -19.06872 -8.93813  -19.04426 1.000 17.93273 ? 37  PHE A O   1 
ATOM   280  C CB  . PHE A 1 37  ? -17.31194 -6.52713  -19.06586 1.000 16.10294 ? 37  PHE A CB  1 
ATOM   281  C CG  . PHE A 1 37  ? -17.48588 -5.66112  -20.28703 1.000 17.97326 ? 37  PHE A CG  1 
ATOM   282  C CD1 . PHE A 1 37  ? -18.63013 -5.73851  -21.05100 1.000 17.43533 ? 37  PHE A CD1 1 
ATOM   283  C CD2 . PHE A 1 37  ? -16.51665 -4.72318  -20.62783 1.000 20.09487 ? 37  PHE A CD2 1 
ATOM   284  C CE1 . PHE A 1 37  ? -18.80375 -4.93447  -22.15350 1.000 24.52302 ? 37  PHE A CE1 1 
ATOM   285  C CE2 . PHE A 1 37  ? -16.67554 -3.91019  -21.73336 1.000 19.34875 ? 37  PHE A CE2 1 
ATOM   286  C CZ  . PHE A 1 37  ? -17.81989 -4.01028  -22.49971 1.000 21.12599 ? 37  PHE A CZ  1 
ATOM   287  N N   . LEU A 1 38  ? -18.15910 -9.25126  -21.08493 1.000 12.83884 ? 38  LEU A N   1 
ATOM   288  C CA  . LEU A 1 38  ? -19.27176 -10.07877 -21.53060 1.000 13.77574 ? 38  LEU A CA  1 
ATOM   289  C C   . LEU A 1 38  ? -19.06579 -11.56871 -21.27887 1.000 14.39696 ? 38  LEU A C   1 
ATOM   290  O O   . LEU A 1 38  ? -19.95003 -12.35985 -21.61977 1.000 17.41019 ? 38  LEU A O   1 
ATOM   291  C CB  . LEU A 1 38  ? -19.57112 -9.84838  -23.01453 1.000 16.06031 ? 38  LEU A CB  1 
ATOM   292  C CG  . LEU A 1 38  ? -20.03482 -8.43816  -23.37680 1.000 16.85582 ? 38  LEU A CG  1 
ATOM   293  C CD1 . LEU A 1 38  ? -20.23319 -8.34516  -24.87027 1.000 19.99072 ? 38  LEU A CD1 1 
ATOM   294  C CD2 . LEU A 1 38  ? -21.33484 -8.07799  -22.61358 1.000 17.60277 ? 38  LEU A CD2 1 
ATOM   295  N N   . ALA A 1 39  ? -17.95046 -11.97828 -20.67633 1.000 13.97213 ? 39  ALA A N   1 
ATOM   296  C CA  . ALA A 1 39  ? -17.69800 -13.38817 -20.39484 1.000 11.17831 ? 39  ALA A CA  1 
ATOM   297  C C   . ALA A 1 39  ? -17.90391 -13.65201 -18.90313 1.000 12.82559 ? 39  ALA A C   1 
ATOM   298  O O   . ALA A 1 39  ? -17.27212 -13.01137 -18.05427 1.000 13.11738 ? 39  ALA A O   1 
ATOM   299  C CB  . ALA A 1 39  ? -16.28546 -13.80225 -20.83074 1.000 11.97817 ? 39  ALA A CB  1 
ATOM   300  N N   . GLN A 1 40  ? -18.80832 -14.57450 -18.59109 1.000 12.88316 ? 40  GLN A N   1 
ATOM   301  C CA  . GLN A 1 40  ? -19.02753 -15.02216 -17.22375 1.000 12.55043 ? 40  GLN A CA  1 
ATOM   302  C C   . GLN A 1 40  ? -18.38285 -16.38877 -17.06166 1.000 16.72611 ? 40  GLN A C   1 
ATOM   303  O O   . GLN A 1 40  ? -18.52240 -17.25296 -17.93433 1.000 11.22531 ? 40  GLN A O   1 
ATOM   304  C CB  . GLN A 1 40  ? -20.52003 -15.10882 -16.89822 1.000 11.51969 ? 40  GLN A CB  1 
ATOM   305  C CG  . GLN A 1 40  ? -20.79171 -15.77362 -15.54345 1.000 15.07495 ? 40  GLN A CG  1 
ATOM   306  C CD  . GLN A 1 40  ? -22.26380 -15.78603 -15.13302 1.000 18.36683 ? 40  GLN A CD  1 
ATOM   307  O OE1 . GLN A 1 40  ? -22.65276 -16.58080 -14.27903 1.000 17.12418 ? 40  GLN A OE1 1 
ATOM   308  N NE2 . GLN A 1 40  ? -23.07325 -14.89775 -15.71608 1.000 12.91294 ? 40  GLN A NE2 1 
ATOM   309  N N   . VAL A 1 41  ? -17.66246 -16.57348 -15.95509 1.000 12.96390 ? 41  VAL A N   1 
ATOM   310  C CA  . VAL A 1 41  ? -17.14620 -17.88015 -15.56141 1.000 13.58400 ? 41  VAL A CA  1 
ATOM   311  C C   . VAL A 1 41  ? -17.78763 -18.19933 -14.21754 1.000 14.05437 ? 41  VAL A C   1 
ATOM   312  O O   . VAL A 1 41  ? -17.68086 -17.41442 -13.26738 1.000 15.27489 ? 41  VAL A O   1 
ATOM   313  C CB  . VAL A 1 41  ? -15.61112 -17.90288 -15.48631 1.000 11.90710 ? 41  VAL A CB  1 
ATOM   314  C CG1 . VAL A 1 41  ? -15.11522 -19.26554 -15.01055 1.000 14.25649 ? 41  VAL A CG1 1 
ATOM   315  C CG2 . VAL A 1 41  ? -15.00083 -17.57758 -16.85835 1.000 10.07586 ? 41  VAL A CG2 1 
ATOM   316  N N   . ASN A 1 42  ? -18.49439 -19.31734 -14.15927 1.000 10.55443 ? 42  ASN A N   1 
ATOM   317  C CA  . ASN A 1 42  ? -19.38478 -19.65391 -13.05281 1.000 12.11881 ? 42  ASN A CA  1 
ATOM   318  C C   . ASN A 1 42  ? -18.93314 -20.99790 -12.47345 1.000 13.57909 ? 42  ASN A C   1 
ATOM   319  O O   . ASN A 1 42  ? -19.17647 -22.05261 -13.06404 1.000 14.21909 ? 42  ASN A O   1 
ATOM   320  C CB  . ASN A 1 42  ? -20.82582 -19.68528 -13.55373 1.000 11.89817 ? 42  ASN A CB  1 
ATOM   321  C CG  . ASN A 1 42  ? -21.83690 -19.72722 -12.43271 1.000 16.26157 ? 42  ASN A CG  1 
ATOM   322  O OD1 . ASN A 1 42  ? -21.67127 -20.48156 -11.49239 1.000 18.38705 ? 42  ASN A OD1 1 
ATOM   323  N ND2 . ASN A 1 42  ? -22.91278 -18.93938 -12.54510 1.000 13.07314 ? 42  ASN A ND2 1 
ATOM   324  N N   . PHE A 1 43  ? -18.27318 -20.96682 -11.31667 1.000 14.30640 ? 43  PHE A N   1 
ATOM   325  C CA  . PHE A 1 43  ? -17.74931 -22.18552 -10.70914 1.000 11.08310 ? 43  PHE A CA  1 
ATOM   326  C C   . PHE A 1 43  ? -18.84044 -22.91632 -9.92552  1.000 14.32522 ? 43  PHE A C   1 
ATOM   327  O O   . PHE A 1 43  ? -19.49325 -22.33897 -9.04957  1.000 13.90974 ? 43  PHE A O   1 
ATOM   328  C CB  . PHE A 1 43  ? -16.57280 -21.84974 -9.79538  1.000 8.78740  ? 43  PHE A CB  1 
ATOM   329  C CG  . PHE A 1 43  ? -15.34847 -21.41631 -10.54786 1.000 9.83737  ? 43  PHE A CG  1 
ATOM   330  C CD1 . PHE A 1 43  ? -14.54225 -22.35631 -11.16163 1.000 9.41851  ? 43  PHE A CD1 1 
ATOM   331  C CD2 . PHE A 1 43  ? -15.05836 -20.06719 -10.71287 1.000 12.37096 ? 43  PHE A CD2 1 
ATOM   332  C CE1 . PHE A 1 43  ? -13.42528 -21.96587 -11.89608 1.000 10.49302 ? 43  PHE A CE1 1 
ATOM   333  C CE2 . PHE A 1 43  ? -13.95221 -19.66477 -11.43822 1.000 12.70366 ? 43  PHE A CE2 1 
ATOM   334  C CZ  . PHE A 1 43  ? -13.13023 -20.62016 -12.02491 1.000 13.74837 ? 43  PHE A CZ  1 
ATOM   335  N N   . GLN A 1 44  ? -18.99542 -24.20463 -10.21832 1.000 13.11933 ? 44  GLN A N   1 
ATOM   336  C CA  . GLN A 1 44  ? -19.94816 -25.07761 -9.54936  1.000 14.93774 ? 44  GLN A CA  1 
ATOM   337  C C   . GLN A 1 44  ? -19.13445 -26.14305 -8.84259  1.000 16.10112 ? 44  GLN A C   1 
ATOM   338  O O   . GLN A 1 44  ? -18.53192 -27.00164 -9.49632  1.000 13.55963 ? 44  GLN A O   1 
ATOM   339  C CB  . GLN A 1 44  ? -20.92604 -25.68832 -10.55349 1.000 14.01557 ? 44  GLN A CB  1 
ATOM   340  C CG  . GLN A 1 44  ? -21.78017 -24.62764 -11.26964 1.000 13.31025 ? 44  GLN A CG  1 
ATOM   341  C CD  . GLN A 1 44  ? -22.82240 -24.01438 -10.34487 1.000 18.25827 ? 44  GLN A CD  1 
ATOM   342  O OE1 . GLN A 1 44  ? -23.59850 -24.72825 -9.70998  1.000 21.61995 ? 44  GLN A OE1 1 
ATOM   343  N NE2 . GLN A 1 44  ? -22.81940 -22.69010 -10.23782 1.000 13.27508 ? 44  GLN A NE2 1 
ATOM   344  N N   . GLU A 1 45  ? -19.08239 -26.06612 -7.51266  1.000 16.94683 ? 45  GLU A N   1 
ATOM   345  C CA  . GLU A 1 45  ? -18.28412 -26.98217 -6.71291  1.000 13.21341 ? 45  GLU A CA  1 
ATOM   346  C C   . GLU A 1 45  ? -19.15745 -28.06792 -6.11181  1.000 17.49054 ? 45  GLU A C   1 
ATOM   347  O O   . GLU A 1 45  ? -20.29875 -27.81050 -5.71599  1.000 13.54996 ? 45  GLU A O   1 
ATOM   348  C CB  . GLU A 1 45  ? -17.57200 -26.22591 -5.59332  1.000 17.11002 ? 45  GLU A CB  1 
ATOM   349  C CG  . GLU A 1 45  ? -16.52564 -25.25773 -6.09534  1.000 21.28713 ? 45  GLU A CG  1 
ATOM   350  C CD  . GLU A 1 45  ? -15.99589 -24.37092 -4.98496  1.000 21.14985 ? 45  GLU A CD  1 
ATOM   351  O OE1 . GLU A 1 45  ? -16.80229 -23.65211 -4.36950  1.000 19.98771 ? 45  GLU A OE1 1 
ATOM   352  O OE2 . GLU A 1 45  ? -14.78024 -24.40510 -4.73364  1.000 24.95371 ? 45  GLU A OE2 1 
ATOM   353  N N   . GLN A 1 46  ? -18.60422 -29.27416 -6.02028  1.000 15.16387 ? 46  GLN A N   1 
ATOM   354  C CA  . GLN A 1 46  ? -19.27640 -30.41975 -5.42953  1.000 17.45849 ? 46  GLN A CA  1 
ATOM   355  C C   . GLN A 1 46  ? -18.23716 -31.21894 -4.66243  1.000 19.09372 ? 46  GLN A C   1 
ATOM   356  O O   . GLN A 1 46  ? -17.04997 -31.16415 -4.99691  1.000 19.62279 ? 46  GLN A O   1 
ATOM   357  C CB  . GLN A 1 46  ? -19.92698 -31.31078 -6.50526  1.000 16.10828 ? 46  GLN A CB  1 
ATOM   358  C CG  . GLN A 1 46  ? -21.13839 -30.69337 -7.19674  1.000 15.15172 ? 46  GLN A CG  1 
ATOM   359  C CD  . GLN A 1 46  ? -22.37915 -30.68070 -6.31613  1.000 18.66518 ? 46  GLN A CD  1 
ATOM   360  O OE1 . GLN A 1 46  ? -22.64217 -31.64255 -5.60314  1.000 20.29409 ? 46  GLN A OE1 1 
ATOM   361  N NE2 . GLN A 1 46  ? -23.15494 -29.58962 -6.37205  1.000 13.84825 ? 46  GLN A NE2 1 
ATOM   362  N N   . PRO A 1 47  ? -18.64089 -31.96795 -3.64066  1.000 20.58468 ? 47  PRO A N   1 
ATOM   363  C CA  . PRO A 1 47  ? -17.64973 -32.74175 -2.88371  1.000 19.03026 ? 47  PRO A CA  1 
ATOM   364  C C   . PRO A 1 47  ? -16.97211 -33.78296 -3.76047  1.000 23.25552 ? 47  PRO A C   1 
ATOM   365  O O   . PRO A 1 47  ? -17.56543 -34.32443 -4.70174  1.000 18.91082 ? 47  PRO A O   1 
ATOM   366  C CB  . PRO A 1 47  ? -18.47713 -33.39508 -1.76809  1.000 21.47018 ? 47  PRO A CB  1 
ATOM   367  C CG  . PRO A 1 47  ? -19.88651 -33.32993 -2.23415  1.000 23.45132 ? 47  PRO A CG  1 
ATOM   368  C CD  . PRO A 1 47  ? -19.97972 -32.06092 -3.03817  1.000 20.65550 ? 47  PRO A CD  1 
ATOM   369  N N   . ALA A 1 48  ? -15.70760 -34.06086 -3.44150  1.000 21.08575 ? 48  ALA A N   1 
ATOM   370  C CA  . ALA A 1 48  ? -14.98189 -35.09650 -4.16442  1.000 19.90846 ? 48  ALA A CA  1 
ATOM   371  C C   . ALA A 1 48  ? -15.73899 -36.41089 -4.07908  1.000 20.97497 ? 48  ALA A C   1 
ATOM   372  O O   . ALA A 1 48  ? -16.29156 -36.76008 -3.03246  1.000 20.85279 ? 48  ALA A O   1 
ATOM   373  C CB  . ALA A 1 48  ? -13.57359 -35.26676 -3.59904  1.000 24.04750 ? 48  ALA A CB  1 
ATOM   374  N N   . GLY A 1 49  ? -15.78356 -37.13426 -5.19727  1.000 16.90170 ? 49  GLY A N   1 
ATOM   375  C CA  . GLY A 1 49  ? -16.49544 -38.38907 -5.26175  1.000 18.26578 ? 49  GLY A CA  1 
ATOM   376  C C   . GLY A 1 49  ? -17.83259 -38.32166 -5.96235  1.000 17.53205 ? 49  GLY A C   1 
ATOM   377  O O   . GLY A 1 49  ? -18.49216 -39.35628 -6.09391  1.000 16.96818 ? 49  GLY A O   1 
ATOM   378  N N   . ASN A 1 50  ? -18.26227 -37.13601 -6.39434  1.000 13.16098 ? 50  ASN A N   1 
ATOM   379  C CA  . ASN A 1 50  ? -19.50457 -36.98157 -7.13665  1.000 14.49862 ? 50  ASN A CA  1 
ATOM   380  C C   . ASN A 1 50  ? -19.31947 -37.14603 -8.64616  1.000 18.12112 ? 50  ASN A C   1 
ATOM   381  O O   . ASN A 1 50  ? -20.31115 -37.13193 -9.38693  1.000 15.65451 ? 50  ASN A O   1 
ATOM   382  C CB  . ASN A 1 50  ? -20.12160 -35.60925 -6.81888  1.000 16.30766 ? 50  ASN A CB  1 
ATOM   383  C CG  . ASN A 1 50  ? -20.97766 -35.63785 -5.56492  1.000 21.34608 ? 50  ASN A CG  1 
ATOM   384  O OD1 . ASN A 1 50  ? -20.90213 -36.59455 -4.79278  1.000 24.04254 ? 50  ASN A OD1 1 
ATOM   385  N ND2 . ASN A 1 50  ? -21.77677 -34.58297 -5.33572  1.000 18.38168 ? 50  ASN A ND2 1 
ATOM   386  N N   . VAL A 1 51  ? -18.08732 -37.31848 -9.12085  1.000 13.22964 ? 51  VAL A N   1 
ATOM   387  C CA  . VAL A 1 51  ? -17.80371 -37.53800 -10.54072 1.000 14.55992 ? 51  VAL A CA  1 
ATOM   388  C C   . VAL A 1 51  ? -17.44776 -39.00596 -10.74741 1.000 13.72419 ? 51  VAL A C   1 
ATOM   389  O O   . VAL A 1 51  ? -16.66092 -39.58007 -9.98033  1.000 17.12902 ? 51  VAL A O   1 
ATOM   390  C CB  . VAL A 1 51  ? -16.66718 -36.62177 -11.03316 1.000 17.48487 ? 51  VAL A CB  1 
ATOM   391  C CG1 . VAL A 1 51  ? -16.33523 -36.88717 -12.52313 1.000 14.83294 ? 51  VAL A CG1 1 
ATOM   392  C CG2 . VAL A 1 51  ? -17.02188 -35.14890 -10.79283 1.000 17.17466 ? 51  VAL A CG2 1 
ATOM   393  N N   . PHE A 1 52  ? -18.02518 -39.61503 -11.77706 1.000 14.38668 ? 52  PHE A N   1 
ATOM   394  C CA  . PHE A 1 52  ? -17.73923 -40.99489 -12.14483 1.000 14.90605 ? 52  PHE A CA  1 
ATOM   395  C C   . PHE A 1 52  ? -17.36536 -41.00540 -13.61947 1.000 15.69147 ? 52  PHE A C   1 
ATOM   396  O O   . PHE A 1 52  ? -18.01620 -40.34279 -14.43158 1.000 13.00440 ? 52  PHE A O   1 
ATOM   397  C CB  . PHE A 1 52  ? -18.95583 -41.90665 -11.89729 1.000 14.04902 ? 52  PHE A CB  1 
ATOM   398  C CG  . PHE A 1 52  ? -19.28604 -42.09094 -10.42862 1.000 15.24941 ? 52  PHE A CG  1 
ATOM   399  C CD1 . PHE A 1 52  ? -19.94249 -41.08466 -9.72905  1.000 17.77046 ? 52  PHE A CD1 1 
ATOM   400  C CD2 . PHE A 1 52  ? -18.98185 -43.27357 -9.76948  1.000 19.80222 ? 52  PHE A CD2 1 
ATOM   401  C CE1 . PHE A 1 52  ? -20.25410 -41.23030 -8.37865  1.000 20.77647 ? 52  PHE A CE1 1 
ATOM   402  C CE2 . PHE A 1 52  ? -19.29551 -43.43688 -8.41132  1.000 17.30464 ? 52  PHE A CE2 1 
ATOM   403  C CZ  . PHE A 1 52  ? -19.91824 -42.41071 -7.71557  1.000 20.38900 ? 52  PHE A CZ  1 
ATOM   404  N N   . LEU A 1 53  ? -16.30111 -41.72759 -13.96013 1.000 14.50458 ? 53  LEU A N   1 
ATOM   405  C CA  . LEU A 1 53  ? -15.89018 -41.90647 -15.34662 1.000 15.31115 ? 53  LEU A CA  1 
ATOM   406  C C   . LEU A 1 53  ? -15.90572 -43.39828 -15.60602 1.000 18.92446 ? 53  LEU A C   1 
ATOM   407  O O   . LEU A 1 53  ? -15.26654 -44.15348 -14.86819 1.000 14.92215 ? 53  LEU A O   1 
ATOM   408  C CB  . LEU A 1 53  ? -14.49434 -41.33717 -15.59827 1.000 12.75919 ? 53  LEU A CB  1 
ATOM   409  C CG  . LEU A 1 53  ? -14.31001 -39.84380 -15.36104 1.000 18.81130 ? 53  LEU A CG  1 
ATOM   410  C CD1 . LEU A 1 53  ? -12.85292 -39.47342 -15.62385 1.000 17.62947 ? 53  LEU A CD1 1 
ATOM   411  C CD2 . LEU A 1 53  ? -15.25978 -39.02529 -16.25563 1.000 15.25615 ? 53  LEU A CD2 1 
ATOM   412  N N   . GLY A 1 54  ? -16.65101 -43.82813 -16.62371 1.000 15.21101 ? 54  GLY A N   1 
ATOM   413  C CA  . GLY A 1 54  ? -16.80690 -45.25834 -16.82747 1.000 18.64044 ? 54  GLY A CA  1 
ATOM   414  C C   . GLY A 1 54  ? -17.33311 -46.00539 -15.61860 1.000 19.32454 ? 54  GLY A C   1 
ATOM   415  O O   . GLY A 1 54  ? -17.03683 -47.19436 -15.45602 1.000 21.51000 ? 54  GLY A O   1 
ATOM   416  N N   . GLY A 1 55  ? -18.13035 -45.35210 -14.77495 1.000 14.53217 ? 55  GLY A N   1 
ATOM   417  C CA  . GLY A 1 55  ? -18.59109 -45.98139 -13.55403 1.000 17.85921 ? 55  GLY A CA  1 
ATOM   418  C C   . GLY A 1 55  ? -17.60791 -45.94780 -12.40288 1.000 18.88456 ? 55  GLY A C   1 
ATOM   419  O O   . GLY A 1 55  ? -17.94662 -46.41890 -11.30868 1.000 23.08199 ? 55  GLY A O   1 
ATOM   420  N N   . VAL A 1 56  ? -16.41414 -45.39675 -12.60317 1.000 17.56250 ? 56  VAL A N   1 
ATOM   421  C CA  . VAL A 1 56  ? -15.36811 -45.37031 -11.58557 1.000 19.34703 ? 56  VAL A CA  1 
ATOM   422  C C   . VAL A 1 56  ? -15.40596 -44.02116 -10.88036 1.000 19.74484 ? 56  VAL A C   1 
ATOM   423  O O   . VAL A 1 56  ? -15.21606 -42.97269 -11.51142 1.000 20.96007 ? 56  VAL A O   1 
ATOM   424  C CB  . VAL A 1 56  ? -13.98806 -45.63739 -12.20445 1.000 19.19091 ? 56  VAL A CB  1 
ATOM   425  C CG1 . VAL A 1 56  ? -12.89407 -45.50955 -11.16133 1.000 20.57370 ? 56  VAL A CG1 1 
ATOM   426  C CG2 . VAL A 1 56  ? -13.96738 -47.01731 -12.83243 1.000 24.03114 ? 56  VAL A CG2 1 
ATOM   427  N N   . GLN A 1 57  ? -15.63165 -44.05464 -9.56968  1.000 16.37629 ? 57  GLN A N   1 
ATOM   428  C CA  . GLN A 1 57  ? -15.64266 -42.83987 -8.76622  1.000 19.10008 ? 57  GLN A CA  1 
ATOM   429  C C   . GLN A 1 57  ? -14.28246 -42.15669 -8.81528  1.000 21.36846 ? 57  GLN A C   1 
ATOM   430  O O   . GLN A 1 57  ? -13.24011 -42.80665 -8.67466  1.000 20.84777 ? 57  GLN A O   1 
ATOM   431  C CB  . GLN A 1 57  ? -16.03302 -43.18554 -7.32465  1.000 24.72527 ? 57  GLN A CB  1 
ATOM   432  C CG  . GLN A 1 57  ? -16.34381 -41.98535 -6.45571  1.000 20.89285 ? 57  GLN A CG  1 
ATOM   433  C CD  . GLN A 1 57  ? -16.52683 -42.36144 -4.99923  1.000 34.44033 ? 57  GLN A CD  1 
ATOM   434  O OE1 . GLN A 1 57  ? -15.98960 -43.36044 -4.53147  1.000 38.06486 ? 57  GLN A OE1 1 
ATOM   435  N NE2 . GLN A 1 57  ? -17.33757 -41.59003 -4.29230  1.000 34.78151 ? 57  GLN A NE2 1 
ATOM   436  N N   . GLN A 1 58  ? -14.29547 -40.84167 -9.02529  1.000 19.04505 ? 58  GLN A N   1 
ATOM   437  C CA  . GLN A 1 58  ? -13.08850 -40.05711 -9.23807  1.000 17.59267 ? 58  GLN A CA  1 
ATOM   438  C C   . GLN A 1 58  ? -12.69422 -39.29806 -7.96818  1.000 18.13636 ? 58  GLN A C   1 
ATOM   439  O O   . GLN A 1 58  ? -13.50259 -39.08807 -7.06595  1.000 18.39824 ? 58  GLN A O   1 
ATOM   440  C CB  . GLN A 1 58  ? -13.30091 -39.06308 -10.38522 1.000 18.11376 ? 58  GLN A CB  1 
ATOM   441  C CG  . GLN A 1 58  ? -13.61533 -39.73320 -11.73248 1.000 20.38123 ? 58  GLN A CG  1 
ATOM   442  C CD  . GLN A 1 58  ? -12.49709 -40.64920 -12.18774 1.000 20.91144 ? 58  GLN A CD  1 
ATOM   443  O OE1 . GLN A 1 58  ? -11.39760 -40.18518 -12.50179 1.000 24.56666 ? 58  GLN A OE1 1 
ATOM   444  N NE2 . GLN A 1 58  ? -12.77537 -41.95025 -12.25762 1.000 20.75368 ? 58  GLN A NE2 1 
ATOM   445  N N   . GLY A 1 59  ? -11.43455 -38.87866 -7.92109  1.000 21.59496 ? 59  GLY A N   1 
ATOM   446  C CA  . GLY A 1 59  ? -10.97716 -37.95744 -6.90372  1.000 21.67579 ? 59  GLY A CA  1 
ATOM   447  C C   . GLY A 1 59  ? -11.33749 -36.53022 -7.26109  1.000 24.36580 ? 59  GLY A C   1 
ATOM   448  O O   . GLY A 1 59  ? -12.25834 -36.26148 -8.03763  1.000 21.71779 ? 59  GLY A O   1 
ATOM   449  N N   . GLY A 1 60  ? -10.58783 -35.59925 -6.68769  1.000 22.17574 ? 60  GLY A N   1 
ATOM   450  C CA  . GLY A 1 60  ? -10.86554 -34.18793 -6.83418  1.000 22.86717 ? 60  GLY A CA  1 
ATOM   451  C C   . GLY A 1 60  ? -10.17079 -33.49408 -7.98344  1.000 20.12815 ? 60  GLY A C   1 
ATOM   452  O O   . GLY A 1 60  ? -10.21181 -32.26051 -8.04958  1.000 19.69961 ? 60  GLY A O   1 
ATOM   453  N N   . ASP A 1 61  ? -9.54668  -34.23408 -8.89967  1.000 18.19594 ? 61  ASP A N   1 
ATOM   454  C CA  . ASP A 1 61  ? -8.71889  -33.65135 -9.94634  1.000 22.21671 ? 61  ASP A CA  1 
ATOM   455  C C   . ASP A 1 61  ? -9.39307  -33.66056 -11.31712 1.000 24.39736 ? 61  ASP A C   1 
ATOM   456  O O   . ASP A 1 61  ? -8.69842  -33.79577 -12.32268 1.000 33.80366 ? 61  ASP A O   1 
ATOM   457  C CB  . ASP A 1 61  ? -7.38214  -34.39702 -10.03418 1.000 27.61850 ? 61  ASP A CB  1 
ATOM   458  C CG  . ASP A 1 61  ? -6.17822  -33.46819 -10.14212 1.000 36.20625 ? 61  ASP A CG  1 
ATOM   459  O OD1 . ASP A 1 61  ? -6.23752  -32.32391 -9.65203  1.000 36.85801 ? 61  ASP A OD1 1 
ATOM   460  O OD2 . ASP A 1 61  ? -5.16396  -33.88448 -10.74701 1.000 37.84629 ? 61  ASP A OD2 1 
ATOM   461  N N   . THR A 1 62  ? -10.71623 -33.55014 -11.39431 1.000 20.46869 ? 62  THR A N   1 
ATOM   462  C CA  . THR A 1 62  ? -11.39712 -33.53492 -12.68316 1.000 20.10985 ? 62  THR A CA  1 
ATOM   463  C C   . THR A 1 62  ? -12.00083 -32.14828 -12.87882 1.000 17.98980 ? 62  THR A C   1 
ATOM   464  O O   . THR A 1 62  ? -12.39863 -31.49081 -11.90902 1.000 17.11262 ? 62  THR A O   1 
ATOM   465  C CB  . THR A 1 62  ? -12.50061 -34.60979 -12.76022 1.000 21.49420 ? 62  THR A CB  1 
ATOM   466  O OG1 . THR A 1 62  ? -11.90505 -35.90762 -12.65256 1.000 36.85428 ? 62  THR A OG1 1 
ATOM   467  C CG2 . THR A 1 62  ? -13.09456 -34.60605 -14.16144 1.000 29.55400 ? 62  THR A CG2 1 
ATOM   468  N N   . ILE A 1 63  ? -12.03283 -31.68169 -14.12928 1.000 16.70939 ? 63  ILE A N   1 
ATOM   469  C CA  . ILE A 1 63  ? -12.67160 -30.41300 -14.47351 1.000 12.39918 ? 63  ILE A CA  1 
ATOM   470  C C   . ILE A 1 63  ? -13.53434 -30.61410 -15.71360 1.000 14.46336 ? 63  ILE A C   1 
ATOM   471  O O   . ILE A 1 63  ? -13.06499 -31.15762 -16.71511 1.000 13.60048 ? 63  ILE A O   1 
ATOM   472  C CB  . ILE A 1 63  ? -11.65210 -29.28218 -14.72503 1.000 16.84642 ? 63  ILE A CB  1 
ATOM   473  C CG1 . ILE A 1 63  ? -10.78031 -29.03168 -13.49905 1.000 23.39223 ? 63  ILE A CG1 1 
ATOM   474  C CG2 . ILE A 1 63  ? -12.37327 -27.97961 -15.07790 1.000 15.58374 ? 63  ILE A CG2 1 
ATOM   475  C CD1 . ILE A 1 63  ? -9.78230  -27.89382 -13.70886 1.000 26.03436 ? 63  ILE A CD1 1 
ATOM   476  N N   . PHE A 1 64  ? -14.77942 -30.13265 -15.66376 1.000 12.92057 ? 64  PHE A N   1 
ATOM   477  C CA  . PHE A 1 64  ? -15.64341 -30.08862 -16.83830 1.000 12.25135 ? 64  PHE A CA  1 
ATOM   478  C C   . PHE A 1 64  ? -16.05021 -28.64239 -17.07892 1.000 11.08408 ? 64  PHE A C   1 
ATOM   479  O O   . PHE A 1 64  ? -16.59079 -27.99761 -16.17760 1.000 11.50563 ? 64  PHE A O   1 
ATOM   480  C CB  . PHE A 1 64  ? -16.87487 -30.97989 -16.65236 1.000 12.17693 ? 64  PHE A CB  1 
ATOM   481  C CG  . PHE A 1 64  ? -17.87617 -30.86712 -17.77338 1.000 12.63846 ? 64  PHE A CG  1 
ATOM   482  C CD1 . PHE A 1 64  ? -17.45492 -30.84870 -19.10653 1.000 11.67443 ? 64  PHE A CD1 1 
ATOM   483  C CD2 . PHE A 1 64  ? -19.23015 -30.73387 -17.48906 1.000 12.59646 ? 64  PHE A CD2 1 
ATOM   484  C CE1 . PHE A 1 64  ? -18.36804 -30.72936 -20.14793 1.000 10.82574 ? 64  PHE A CE1 1 
ATOM   485  C CE2 . PHE A 1 64  ? -20.15770 -30.58398 -18.53503 1.000 11.92718 ? 64  PHE A CE2 1 
ATOM   486  C CZ  . PHE A 1 64  ? -19.71870 -30.58221 -19.85696 1.000 12.75698 ? 64  PHE A CZ  1 
ATOM   487  N N   . VAL A 1 65  ? -15.75782 -28.13170 -18.27597 1.000 10.94066 ? 65  VAL A N   1 
ATOM   488  C CA  . VAL A 1 65  ? -16.11352 -26.77656 -18.69116 1.000 11.27882 ? 65  VAL A CA  1 
ATOM   489  C C   . VAL A 1 65  ? -17.21143 -26.90417 -19.72880 1.000 11.21409 ? 65  VAL A C   1 
ATOM   490  O O   . VAL A 1 65  ? -16.98239 -27.48880 -20.79273 1.000 10.87367 ? 65  VAL A O   1 
ATOM   491  C CB  . VAL A 1 65  ? -14.91495 -26.01648 -19.28642 1.000 11.88442 ? 65  VAL A CB  1 
ATOM   492  C CG1 . VAL A 1 65  ? -15.36091 -24.60707 -19.75514 1.000 12.97567 ? 65  VAL A CG1 1 
ATOM   493  C CG2 . VAL A 1 65  ? -13.75828 -25.91883 -18.28166 1.000 12.87413 ? 65  VAL A CG2 1 
ATOM   494  N N   . HIS A 1 66  ? -18.39811 -26.37129 -19.41769 1.000 11.06495 ? 66  HIS A N   1 
ATOM   495  C CA  . HIS A 1 66  ? -19.53829 -26.32305 -20.33130 1.000 9.13773  ? 66  HIS A CA  1 
ATOM   496  C C   . HIS A 1 66  ? -19.66783 -24.86775 -20.76441 1.000 10.50083 ? 66  HIS A C   1 
ATOM   497  O O   . HIS A 1 66  ? -20.14475 -24.02264 -19.99702 1.000 12.79272 ? 66  HIS A O   1 
ATOM   498  C CB  . HIS A 1 66  ? -20.80825 -26.83621 -19.64249 1.000 10.27724 ? 66  HIS A CB  1 
ATOM   499  C CG  . HIS A 1 66  ? -21.98000 -27.04117 -20.55913 1.000 12.12517 ? 66  HIS A CG  1 
ATOM   500  N ND1 . HIS A 1 66  ? -23.25759 -27.27063 -20.08483 1.000 12.42134 ? 66  HIS A ND1 1 
ATOM   501  C CD2 . HIS A 1 66  ? -22.07624 -27.03805 -21.90895 1.000 12.35839 ? 66  HIS A CD2 1 
ATOM   502  C CE1 . HIS A 1 66  ? -24.08577 -27.41389 -21.10610 1.000 13.14778 ? 66  HIS A CE1 1 
ATOM   503  N NE2 . HIS A 1 66  ? -23.39720 -27.26151 -22.22336 1.000 14.45000 ? 66  HIS A NE2 1 
ATOM   504  N N   . GLY A 1 67  ? -19.19997 -24.57163 -21.97780 1.000 9.60557  ? 67  GLY A N   1 
ATOM   505  C CA  . GLY A 1 67  ? -19.28197 -23.23170 -22.51887 1.000 10.49902 ? 67  GLY A CA  1 
ATOM   506  C C   . GLY A 1 67  ? -20.58687 -23.06071 -23.27056 1.000 13.26076 ? 67  GLY A C   1 
ATOM   507  O O   . GLY A 1 67  ? -20.94113 -23.89169 -24.10965 1.000 13.54050 ? 67  GLY A O   1 
ATOM   508  N N   . LEU A 1 68  ? -21.30916 -21.99056 -22.94487 1.000 10.63602 ? 68  LEU A N   1 
ATOM   509  C CA  . LEU A 1 68  ? -22.57583 -21.64343 -23.58468 1.000 11.58175 ? 68  LEU A CA  1 
ATOM   510  C C   . LEU A 1 68  ? -22.36759 -20.38055 -24.40960 1.000 10.62621 ? 68  LEU A C   1 
ATOM   511  O O   . LEU A 1 68  ? -22.09083 -19.31402 -23.84669 1.000 11.25600 ? 68  LEU A O   1 
ATOM   512  C CB  . LEU A 1 68  ? -23.66981 -21.42966 -22.54014 1.000 11.46986 ? 68  LEU A CB  1 
ATOM   513  C CG  . LEU A 1 68  ? -23.80937 -22.62967 -21.60543 1.000 12.36747 ? 68  LEU A CG  1 
ATOM   514  C CD1 . LEU A 1 68  ? -24.74817 -22.29707 -20.45951 1.000 10.25617 ? 68  LEU A CD1 1 
ATOM   515  C CD2 . LEU A 1 68  ? -24.30848 -23.82082 -22.39929 1.000 13.98226 ? 68  LEU A CD2 1 
ATOM   516  N N   . HIS A 1 69  ? -22.51469 -20.50653 -25.73884 1.000 10.94829 ? 69  HIS A N   1 
ATOM   517  C CA  . HIS A 1 69  ? -22.15037 -19.49215 -26.71887 1.000 10.50721 ? 69  HIS A CA  1 
ATOM   518  C C   . HIS A 1 69  ? -23.34141 -19.08600 -27.58296 1.000 11.19602 ? 69  HIS A C   1 
ATOM   519  O O   . HIS A 1 69  ? -24.29995 -19.84134 -27.72660 1.000 10.91860 ? 69  HIS A O   1 
ATOM   520  C CB  . HIS A 1 69  ? -21.08684 -20.01070 -27.69138 1.000 12.41455 ? 69  HIS A CB  1 
ATOM   521  C CG  . HIS A 1 69  ? -19.75301 -20.28310 -27.07946 1.000 14.33476 ? 69  HIS A CG  1 
ATOM   522  N ND1 . HIS A 1 69  ? -18.74684 -20.91961 -27.77405 1.000 17.68001 ? 69  HIS A ND1 1 
ATOM   523  C CD2 . HIS A 1 69  ? -19.24101 -19.98050 -25.86300 1.000 15.83806 ? 69  HIS A CD2 1 
ATOM   524  C CE1 . HIS A 1 69  ? -17.67694 -21.01572 -27.00374 1.000 15.89925 ? 69  HIS A CE1 1 
ATOM   525  N NE2 . HIS A 1 69  ? -17.94995 -20.45358 -25.83955 1.000 15.74944 ? 69  HIS A NE2 1 
ATOM   526  N N   . ARG A 1 70  ? -23.20344 -17.92666 -28.24232 1.000 10.77140 ? 70  ARG A N   1 
ATOM   527  C CA  . ARG A 1 70  ? -24.06065 -17.57428 -29.36838 1.000 12.61570 ? 70  ARG A CA  1 
ATOM   528  C C   . ARG A 1 70  ? -23.71332 -18.42574 -30.57951 1.000 13.65263 ? 70  ARG A C   1 
ATOM   529  O O   . ARG A 1 70  ? -22.54108 -18.69198 -30.84981 1.000 14.70290 ? 70  ARG A O   1 
ATOM   530  C CB  . ARG A 1 70  ? -23.87903 -16.10080 -29.74653 1.000 10.54149 ? 70  ARG A CB  1 
ATOM   531  C CG  . ARG A 1 70  ? -24.45395 -15.12646 -28.73362 1.000 9.54684  ? 70  ARG A CG  1 
ATOM   532  C CD  . ARG A 1 70  ? -23.98458 -13.68874 -29.00448 1.000 15.39269 ? 70  ARG A CD  1 
ATOM   533  N NE  . ARG A 1 70  ? -22.63345 -13.44503 -28.50099 1.000 16.66259 ? 70  ARG A NE  1 
ATOM   534  C CZ  . ARG A 1 70  ? -21.84727 -12.46012 -28.91684 1.000 18.52909 ? 70  ARG A CZ  1 
ATOM   535  N NH1 . ARG A 1 70  ? -22.27471 -11.55630 -29.78556 1.000 15.73147 ? 70  ARG A NH1 1 
ATOM   536  N NH2 . ARG A 1 70  ? -20.61996 -12.35002 -28.41114 1.000 17.43448 ? 70  ARG A NH2 1 
ATOM   537  N N   . GLU A 1 71  ? -24.73890 -18.84879 -31.31721 1.000 11.85540 ? 71  GLU A N   1 
ATOM   538  C CA  . GLU A 1 71  ? -24.53938 -19.40900 -32.64993 1.000 10.30724 ? 71  GLU A CA  1 
ATOM   539  C C   . GLU A 1 71  ? -23.82885 -18.41341 -33.55957 1.000 10.99302 ? 71  GLU A C   1 
ATOM   540  O O   . GLU A 1 71  ? -23.99159 -17.19852 -33.43283 1.000 13.31952 ? 71  GLU A O   1 
ATOM   541  C CB  . GLU A 1 71  ? -25.89260 -19.76298 -33.27118 1.000 13.56524 ? 71  GLU A CB  1 
ATOM   542  C CG  . GLU A 1 71  ? -26.55968 -20.99960 -32.70862 1.000 16.09797 ? 71  GLU A CG  1 
ATOM   543  C CD  . GLU A 1 71  ? -27.93504 -21.21084 -33.31188 1.000 20.29145 ? 71  GLU A CD  1 
ATOM   544  O OE1 . GLU A 1 71  ? -28.34146 -20.40086 -34.17788 1.000 24.09599 ? 71  GLU A OE1 1 
ATOM   545  O OE2 . GLU A 1 71  ? -28.61385 -22.17161 -32.90982 1.000 23.73651 ? 71  GLU A OE2 1 
ATOM   546  N N   . GLY A 1 72  ? -23.03301 -18.93238 -34.50104 1.000 12.55887 ? 72  GLY A N   1 
ATOM   547  C CA  . GLY A 1 72  ? -22.55718 -18.06118 -35.56043 1.000 10.92211 ? 72  GLY A CA  1 
ATOM   548  C C   . GLY A 1 72  ? -21.07330 -18.12974 -35.87235 1.000 14.63176 ? 72  GLY A C   1 
ATOM   549  O O   . GLY A 1 72  ? -20.61893 -17.50450 -36.83443 1.000 13.50719 ? 72  GLY A O   1 
ATOM   550  N N   . ARG A 1 73  ? -20.29933 -18.86031 -35.07792 1.000 14.19897 ? 73  ARG A N   1 
ATOM   551  C CA  . ARG A 1 73  ? -18.86699 -18.97134 -35.32653 1.000 11.60661 ? 73  ARG A CA  1 
ATOM   552  C C   . ARG A 1 73  ? -18.53693 -20.28118 -36.02876 1.000 12.90683 ? 73  ARG A C   1 
ATOM   553  O O   . ARG A 1 73  ? -19.31206 -21.24079 -36.02467 1.000 15.48467 ? 73  ARG A O   1 
ATOM   554  C CB  . ARG A 1 73  ? -18.05980 -18.86850 -34.03263 1.000 14.42458 ? 73  ARG A CB  1 
ATOM   555  C CG  . ARG A 1 73  ? -18.40547 -17.65178 -33.19507 1.000 15.69968 ? 73  ARG A CG  1 
ATOM   556  C CD  . ARG A 1 73  ? -17.29626 -17.33185 -32.21288 1.000 21.55866 ? 73  ARG A CD  1 
ATOM   557  N NE  . ARG A 1 73  ? -17.58717 -16.07349 -31.54294 1.000 17.69580 ? 73  ARG A NE  1 
ATOM   558  C CZ  . ARG A 1 73  ? -18.37855 -15.96230 -30.48826 1.000 18.26341 ? 73  ARG A CZ  1 
ATOM   559  N NH1 . ARG A 1 73  ? -18.91592 -17.03181 -29.91104 1.000 20.69194 ? 73  ARG A NH1 1 
ATOM   560  N NH2 . ARG A 1 73  ? -18.63957 -14.74872 -29.99652 1.000 19.75561 ? 73  ARG A NH2 1 
ATOM   561  N N   . SER A 1 74  ? -17.35602 -20.30256 -36.63670 1.000 11.43574 ? 74  SER A N   1 
ATOM   562  C CA  . SER A 1 74  ? -16.92597 -21.44483 -37.41706 1.000 10.24771 ? 74  SER A CA  1 
ATOM   563  C C   . SER A 1 74  ? -16.46330 -22.58185 -36.51757 1.000 14.18829 ? 74  SER A C   1 
ATOM   564  O O   . SER A 1 74  ? -16.01724 -22.36282 -35.38256 1.000 11.98744 ? 74  SER A O   1 
ATOM   565  C CB  . SER A 1 74  ? -15.79766 -21.02131 -38.34867 1.000 13.36552 ? 74  SER A CB  1 
ATOM   566  O OG  . SER A 1 74  ? -14.61739 -20.78204 -37.59025 1.000 13.44831 ? 74  SER A OG  1 
ATOM   567  N N   . ALA A 1 75  ? -16.56624 -23.80695 -37.05047 1.000 10.49226 ? 75  ALA A N   1 
ATOM   568  C CA  . ALA A 1 75  ? -15.98517 -24.96615 -36.38395 1.000 11.38571 ? 75  ALA A CA  1 
ATOM   569  C C   . ALA A 1 75  ? -14.49702 -24.76219 -36.13827 1.000 12.08784 ? 75  ALA A C   1 
ATOM   570  O O   . ALA A 1 75  ? -13.97423 -25.15312 -35.08597 1.000 14.66906 ? 75  ALA A O   1 
ATOM   571  C CB  . ALA A 1 75  ? -16.20181 -26.22189 -37.21425 1.000 11.72565 ? 75  ALA A CB  1 
ATOM   572  N N   . ASP A 1 76  ? -13.79687 -24.17226 -37.11220 1.000 13.98276 ? 76  ASP A N   1 
ATOM   573  C CA  . ASP A 1 76  ? -12.37743 -23.88251 -36.93816 1.000 14.96168 ? 76  ASP A CA  1 
ATOM   574  C C   . ASP A 1 76  ? -12.12500 -23.06293 -35.68755 1.000 14.48209 ? 76  ASP A C   1 
ATOM   575  O O   . ASP A 1 76  ? -11.23128 -23.37854 -34.89342 1.000 17.58181 ? 76  ASP A O   1 
ATOM   576  C CB  . ASP A 1 76  ? -11.83038 -23.13008 -38.14541 1.000 14.33608 ? 76  ASP A CB  1 
ATOM   577  C CG  . ASP A 1 76  ? -10.34549 -22.82454 -38.00715 1.000 28.57127 ? 76  ASP A CG  1 
ATOM   578  O OD1 . ASP A 1 76  ? -9.56925  -23.73424 -37.65078 1.000 32.98345 ? 76  ASP A OD1 1 
ATOM   579  O OD2 . ASP A 1 76  ? -9.95764  -21.66473 -38.23450 1.000 40.74418 ? 76  ASP A OD2 1 
ATOM   580  N N   . LEU A 1 77  ? -12.87290 -21.97134 -35.52733 1.000 10.23016 ? 77  LEU A N   1 
ATOM   581  C CA  . LEU A 1 77  ? -12.61670 -21.05054 -34.43337 1.000 15.08456 ? 77  LEU A CA  1 
ATOM   582  C C   . LEU A 1 77  ? -13.02140 -21.66751 -33.10471 1.000 14.21496 ? 77  LEU A C   1 
ATOM   583  O O   . LEU A 1 77  ? -12.33360 -21.49075 -32.09680 1.000 13.97822 ? 77  LEU A O   1 
ATOM   584  C CB  . LEU A 1 77  ? -13.35828 -19.73634 -34.68296 1.000 12.03285 ? 77  LEU A CB  1 
ATOM   585  C CG  . LEU A 1 77  ? -13.16307 -18.52910 -33.78780 1.000 19.50734 ? 77  LEU A CG  1 
ATOM   586  C CD1 . LEU A 1 77  ? -13.83266 -18.67621 -32.43933 1.000 23.09800 ? 77  LEU A CD1 1 
ATOM   587  C CD2 . LEU A 1 77  ? -11.65277 -18.35722 -33.61831 1.000 20.99333 ? 77  LEU A CD2 1 
ATOM   588  N N   . LYS A 1 78  ? -14.12862 -22.40176 -33.08796 1.000 11.96336 ? 78  LYS A N   1 
ATOM   589  C CA  . LYS A 1 78  ? -14.54587 -23.05448 -31.85496 1.000 12.87272 ? 78  LYS A CA  1 
ATOM   590  C C   . LYS A 1 78  ? -13.53569 -24.11128 -31.43430 1.000 14.64934 ? 78  LYS A C   1 
ATOM   591  O O   . LYS A 1 78  ? -13.28895 -24.29872 -30.23835 1.000 14.32230 ? 78  LYS A O   1 
ATOM   592  C CB  . LYS A 1 78  ? -15.94044 -23.66154 -32.03494 1.000 11.97249 ? 78  LYS A CB  1 
ATOM   593  C CG  . LYS A 1 78  ? -17.05275 -22.59289 -32.07966 1.000 14.64307 ? 78  LYS A CG  1 
ATOM   594  C CD  . LYS A 1 78  ? -18.42661 -23.23393 -32.21598 1.000 11.62030 ? 78  LYS A CD  1 
ATOM   595  C CE  . LYS A 1 78  ? -18.64085 -23.66274 -33.67786 1.000 14.50104 ? 78  LYS A CE  1 
ATOM   596  N NZ  . LYS A 1 78  ? -19.97250 -24.27871 -33.87377 1.000 12.45221 ? 78  LYS A NZ  1 
ATOM   597  N N   . GLY A 1 79  ? -12.92716 -24.79859 -32.40447 1.000 12.72311 ? 79  GLY A N   1 
ATOM   598  C CA  . GLY A 1 79  ? -11.85634 -25.72943 -32.07830 1.000 16.35879 ? 79  GLY A CA  1 
ATOM   599  C C   . GLY A 1 79  ? -10.64233 -25.04175 -31.48033 1.000 13.61462 ? 79  GLY A C   1 
ATOM   600  O O   . GLY A 1 79  ? -10.08208 -25.50411 -30.48347 1.000 12.59937 ? 79  GLY A O   1 
ATOM   601  N N   . GLN A 1 80  ? -10.21301 -23.92894 -32.07657 1.000 14.31753 ? 80  GLN A N   1 
ATOM   602  C CA  . GLN A 1 80  ? -9.08325  -23.19821 -31.50271 1.000 13.91410 ? 80  GLN A CA  1 
ATOM   603  C C   . GLN A 1 80  ? -9.38649  -22.71170 -30.09285 1.000 17.19134 ? 80  GLN A C   1 
ATOM   604  O O   . GLN A 1 80  ? -8.49578  -22.67709 -29.22819 1.000 14.39172 ? 80  GLN A O   1 
ATOM   605  C CB  . GLN A 1 80  ? -8.71362  -22.00150 -32.37178 1.000 16.03159 ? 80  GLN A CB  1 
ATOM   606  C CG  . GLN A 1 80  ? -8.32820  -22.30883 -33.78692 1.000 17.39899 ? 80  GLN A CG  1 
ATOM   607  C CD  . GLN A 1 80  ? -8.05305  -21.01906 -34.54247 1.000 27.34392 ? 80  GLN A CD  1 
ATOM   608  O OE1 . GLN A 1 80  ? -7.54337  -20.05584 -33.96021 1.000 31.72247 ? 80  GLN A OE1 1 
ATOM   609  N NE2 . GLN A 1 80  ? -8.41823  -20.97611 -35.82513 1.000 24.09645 ? 80  GLN A NE2 1 
ATOM   610  N N   . LEU A 1 81  ? -10.62681 -22.28282 -29.85454 1.000 13.36394 ? 81  LEU A N   1 
ATOM   611  C CA  . LEU A 1 81  ? -10.98690 -21.75552 -28.54468 1.000 12.80870 ? 81  LEU A CA  1 
ATOM   612  C C   . LEU A 1 81  ? -11.08190 -22.86613 -27.50573 1.000 13.65027 ? 81  LEU A C   1 
ATOM   613  O O   . LEU A 1 81  ? -10.61710 -22.70310 -26.36831 1.000 13.47423 ? 81  LEU A O   1 
ATOM   614  C CB  . LEU A 1 81  ? -12.29935 -20.96485 -28.64945 1.000 17.56611 ? 81  LEU A CB  1 
ATOM   615  C CG  . LEU A 1 81  ? -12.93372 -20.38704 -27.37715 1.000 13.18157 ? 81  LEU A CG  1 
ATOM   616  C CD1 . LEU A 1 81  ? -12.01429 -19.42667 -26.63312 1.000 14.47814 ? 81  LEU A CD1 1 
ATOM   617  C CD2 . LEU A 1 81  ? -14.26609 -19.68340 -27.70085 1.000 13.87537 ? 81  LEU A CD2 1 
ATOM   618  N N   . ALA A 1 82  ? -11.67290 -24.00261 -27.86622 1.000 10.55907 ? 82  ALA A N   1 
ATOM   619  C CA  . ALA A 1 82  ? -11.69561 -25.12647 -26.93719 1.000 11.72795 ? 82  ALA A CA  1 
ATOM   620  C C   . ALA A 1 82  ? -10.28722 -25.58691 -26.60462 1.000 12.96365 ? 82  ALA A C   1 
ATOM   621  O O   . ALA A 1 82  ? -9.98194  -25.87824 -25.44097 1.000 14.42453 ? 82  ALA A O   1 
ATOM   622  C CB  . ALA A 1 82  ? -12.50528 -26.28570 -27.51478 1.000 12.41353 ? 82  ALA A CB  1 
ATOM   623  N N   . GLN A 1 83  ? -9.40623  -25.65372 -27.61298 1.000 13.89403 ? 83  GLN A N   1 
ATOM   624  C CA  . GLN A 1 83  ? -8.02737  -26.06086 -27.33472 1.000 15.71864 ? 83  GLN A CA  1 
ATOM   625  C C   . GLN A 1 83  ? -7.32335  -25.06625 -26.42258 1.000 15.01163 ? 83  GLN A C   1 
ATOM   626  O O   . GLN A 1 83  ? -6.57945  -25.46249 -25.51559 1.000 16.53424 ? 83  GLN A O   1 
ATOM   627  C CB  . GLN A 1 83  ? -7.23486  -26.21287 -28.62797 1.000 16.17275 ? 83  GLN A CB  1 
ATOM   628  C CG  . GLN A 1 83  ? -5.83510  -26.80681 -28.41314 1.000 20.57281 ? 83  GLN A CG  1 
ATOM   629  C CD  . GLN A 1 83  ? -5.87306  -28.22001 -27.84439 1.000 21.79092 ? 83  GLN A CD  1 
ATOM   630  O OE1 . GLN A 1 83  ? -6.38374  -29.14268 -28.48288 1.000 21.44792 ? 83  GLN A OE1 1 
ATOM   631  N NE2 . GLN A 1 83  ? -5.32633  -28.39655 -26.64473 1.000 23.43926 ? 83  GLN A NE2 1 
ATOM   632  N N   . ARG A 1 84  ? -7.49896  -23.76825 -26.67039 1.000 15.92413 ? 84  ARG A N   1 
ATOM   633  C CA  . ARG A 1 84  ? -6.82704  -22.79376 -25.81542 1.000 17.24198 ? 84  ARG A CA  1 
ATOM   634  C C   . ARG A 1 84  ? -7.35466  -22.84833 -24.39427 1.000 18.19539 ? 84  ARG A C   1 
ATOM   635  O O   . ARG A 1 84  ? -6.58957  -22.65775 -23.44131 1.000 16.09234 ? 84  ARG A O   1 
ATOM   636  C CB  . ARG A 1 84  ? -6.96419  -21.37347 -26.36822 1.000 15.43692 ? 84  ARG A CB  1 
ATOM   637  C CG  . ARG A 1 84  ? -6.06883  -20.39804 -25.58638 1.000 23.21927 ? 84  ARG A CG  1 
ATOM   638  C CD  . ARG A 1 84  ? -6.08272  -18.99674 -26.14580 1.000 21.69745 ? 84  ARG A CD  1 
ATOM   639  N NE  . ARG A 1 84  ? -5.71911  -18.02427 -25.12308 1.000 22.97259 ? 84  ARG A NE  1 
ATOM   640  C CZ  . ARG A 1 84  ? -5.55653  -16.73169 -25.35855 1.000 26.15676 ? 84  ARG A CZ  1 
ATOM   641  N NH1 . ARG A 1 84  ? -5.67789  -16.23296 -26.58074 1.000 30.14338 ? 84  ARG A NH1 1 
ATOM   642  N NH2 . ARG A 1 84  ? -5.25604  -15.92046 -24.34661 1.000 23.56093 ? 84  ARG A NH2 1 
ATOM   643  N N   . ILE A 1 85  ? -8.64725  -23.12889 -24.22486 1.000 14.38126 ? 85  ILE A N   1 
ATOM   644  C CA  . ILE A 1 85  ? -9.18155  -23.29805 -22.87893 1.000 12.91769 ? 85  ILE A CA  1 
ATOM   645  C C   . ILE A 1 85  ? -8.55164  -24.51713 -22.20252 1.000 18.54146 ? 85  ILE A C   1 
ATOM   646  O O   . ILE A 1 85  ? -8.18199  -24.45921 -21.02336 1.000 15.73710 ? 85  ILE A O   1 
ATOM   647  C CB  . ILE A 1 85  ? -10.72072 -23.37296 -22.93203 1.000 13.83721 ? 85  ILE A CB  1 
ATOM   648  C CG1 . ILE A 1 85  ? -11.29193 -21.97409 -23.13359 1.000 17.15483 ? 85  ILE A CG1 1 
ATOM   649  C CG2 . ILE A 1 85  ? -11.30057 -23.98091 -21.65382 1.000 14.84761 ? 85  ILE A CG2 1 
ATOM   650  C CD1 . ILE A 1 85  ? -12.77731 -21.96301 -23.48947 1.000 19.16509 ? 85  ILE A CD1 1 
ATOM   651  N N   . VAL A 1 86  ? -8.37814  -25.62635 -22.93571 1.000 13.83110 ? 86  VAL A N   1 
ATOM   652  C CA  . VAL A 1 86  ? -7.68803  -26.78663 -22.35562 1.000 15.09396 ? 86  VAL A CA  1 
ATOM   653  C C   . VAL A 1 86  ? -6.26991  -26.40303 -21.93423 1.000 15.22031 ? 86  VAL A C   1 
ATOM   654  O O   . VAL A 1 86  ? -5.83361  -26.69165 -20.80963 1.000 17.70981 ? 86  VAL A O   1 
ATOM   655  C CB  . VAL A 1 86  ? -7.66488  -27.96967 -23.34280 1.000 15.32832 ? 86  VAL A CB  1 
ATOM   656  C CG1 . VAL A 1 86  ? -6.68516  -29.06697 -22.85432 1.000 17.58483 ? 86  VAL A CG1 1 
ATOM   657  C CG2 . VAL A 1 86  ? -9.05295  -28.55020 -23.53467 1.000 15.07409 ? 86  VAL A CG2 1 
ATOM   658  N N   . ASP A 1 87  ? -5.52276  -25.76339 -22.84048 1.000 15.67283 ? 87  ASP A N   1 
ATOM   659  C CA  . ASP A 1 87  ? -4.12374  -25.43501 -22.55322 1.000 16.74154 ? 87  ASP A CA  1 
ATOM   660  C C   . ASP A 1 87  ? -4.01096  -24.44904 -21.39562 1.000 20.17950 ? 87  ASP A C   1 
ATOM   661  O O   . ASP A 1 87  ? -3.19720  -24.63614 -20.47900 1.000 18.03520 ? 87  ASP A O   1 
ATOM   662  C CB  . ASP A 1 87  ? -3.42676  -24.85912 -23.79163 1.000 22.26201 ? 87  ASP A CB  1 
ATOM   663  C CG  . ASP A 1 87  ? -3.33299  -25.84892 -24.94464 1.000 22.56015 ? 87  ASP A CG  1 
ATOM   664  O OD1 . ASP A 1 87  ? -3.49653  -27.07031 -24.73223 1.000 26.51758 ? 87  ASP A OD1 1 
ATOM   665  O OD2 . ASP A 1 87  ? -3.02203  -25.39807 -26.07235 1.000 25.18288 ? 87  ASP A OD2 1 
ATOM   666  N N   . ASP A 1 88  ? -4.80205  -23.37311 -21.42881 1.000 14.56313 ? 88  ASP A N   1 
ATOM   667  C CA  . ASP A 1 88  ? -4.62224  -22.32101 -20.43625 1.000 18.49998 ? 88  ASP A CA  1 
ATOM   668  C C   . ASP A 1 88  ? -5.23304  -22.69227 -19.09045 1.000 19.62808 ? 88  ASP A C   1 
ATOM   669  O O   . ASP A 1 88  ? -4.71476  -22.27957 -18.04606 1.000 19.08363 ? 88  ASP A O   1 
ATOM   670  C CB  . ASP A 1 88  ? -5.19043  -21.00512 -20.97225 1.000 21.73163 ? 88  ASP A CB  1 
ATOM   671  C CG  . ASP A 1 88  ? -4.40812  -20.48742 -22.17387 1.000 21.81307 ? 88  ASP A CG  1 
ATOM   672  O OD1 . ASP A 1 88  ? -3.43980  -21.16729 -22.59137 1.000 23.13054 ? 88  ASP A OD1 1 
ATOM   673  O OD2 . ASP A 1 88  ? -4.75490  -19.40726 -22.71065 1.000 23.63510 ? 88  ASP A OD2 1 
ATOM   674  N N   . VAL A 1 89  ? -6.30379  -23.49131 -19.08024 1.000 16.41112 ? 89  VAL A N   1 
ATOM   675  C CA  . VAL A 1 89  ? -6.83453  -23.93955 -17.79591 1.000 17.76851 ? 89  VAL A CA  1 
ATOM   676  C C   . VAL A 1 89  ? -5.89007  -24.96271 -17.17601 1.000 15.70141 ? 89  VAL A C   1 
ATOM   677  O O   . VAL A 1 89  ? -5.72857  -25.00411 -15.95170 1.000 17.08346 ? 89  VAL A O   1 
ATOM   678  C CB  . VAL A 1 89  ? -8.25698  -24.50557 -17.96764 1.000 14.70945 ? 89  VAL A CB  1 
ATOM   679  C CG1 . VAL A 1 89  ? -8.69846  -25.23565 -16.71062 1.000 17.99830 ? 89  VAL A CG1 1 
ATOM   680  C CG2 . VAL A 1 89  ? -9.23800  -23.38121 -18.31612 1.000 15.09240 ? 89  VAL A CG2 1 
ATOM   681  N N   . SER A 1 90  ? -5.22964  -25.77871 -18.00233 1.000 13.13296 ? 90  SER A N   1 
ATOM   682  C CA  . SER A 1 90  ? -4.23359  -26.70965 -17.47082 1.000 17.25759 ? 90  SER A CA  1 
ATOM   683  C C   . SER A 1 90  ? -3.16996  -25.97625 -16.66636 1.000 19.57510 ? 90  SER A C   1 
ATOM   684  O O   . SER A 1 90  ? -2.77246  -26.42092 -15.58001 1.000 23.60566 ? 90  SER A O   1 
ATOM   685  C CB  . SER A 1 90  ? -3.58475  -27.48529 -18.61749 1.000 22.07719 ? 90  SER A CB  1 
ATOM   686  O OG  . SER A 1 90  ? -2.58117  -28.34267 -18.13062 1.000 26.27279 ? 90  SER A OG  1 
ATOM   687  N N   . VAL A 1 91  ? -2.70628  -24.83922 -17.18008 1.000 17.54518 ? 91  VAL A N   1 
ATOM   688  C CA  . VAL A 1 91  ? -1.67081  -24.08220 -16.48372 1.000 17.73081 ? 91  VAL A CA  1 
ATOM   689  C C   . VAL A 1 91  ? -2.25517  -23.37064 -15.26731 1.000 20.77033 ? 91  VAL A C   1 
ATOM   690  O O   . VAL A 1 91  ? -1.69518  -23.42650 -14.16610 1.000 19.32373 ? 91  VAL A O   1 
ATOM   691  C CB  . VAL A 1 91  ? -0.99927  -23.09628 -17.45308 1.000 20.02705 ? 91  VAL A CB  1 
ATOM   692  C CG1 . VAL A 1 91  ? -0.12543  -22.10280 -16.67993 1.000 21.70483 ? 91  VAL A CG1 1 
ATOM   693  C CG2 . VAL A 1 91  ? -0.21739  -23.86928 -18.50115 1.000 23.36558 ? 91  VAL A CG2 1 
ATOM   694  N N   . ALA A 1 92  ? -3.40433  -22.70891 -15.44129 1.000 19.52902 ? 92  ALA A N   1 
ATOM   695  C CA  . ALA A 1 92  ? -3.97627  -21.90727 -14.35927 1.000 17.26990 ? 92  ALA A CA  1 
ATOM   696  C C   . ALA A 1 92  ? -4.37861  -22.76176 -13.16160 1.000 21.30041 ? 92  ALA A C   1 
ATOM   697  O O   . ALA A 1 92  ? -4.20441  -22.34617 -12.00657 1.000 20.80634 ? 92  ALA A O   1 
ATOM   698  C CB  . ALA A 1 92  ? -5.18661  -21.11876 -14.86462 1.000 16.01971 ? 92  ALA A CB  1 
ATOM   699  N N   . ALA A 1 93  ? -4.95752  -23.93208 -13.40634 1.000 16.32039 ? 93  ALA A N   1 
ATOM   700  C CA  . ALA A 1 93  ? -5.40756  -24.78460 -12.31887 1.000 16.81403 ? 93  ALA A CA  1 
ATOM   701  C C   . ALA A 1 93  ? -4.35621  -25.81169 -11.92464 1.000 19.98141 ? 93  ALA A C   1 
ATOM   702  O O   . ALA A 1 93  ? -4.60547  -26.61418 -11.02294 1.000 20.53892 ? 93  ALA A O   1 
ATOM   703  C CB  . ALA A 1 93  ? -6.71239  -25.49458 -12.70490 1.000 18.20719 ? 93  ALA A CB  1 
ATOM   704  N N   . GLU A 1 94  ? -3.19792  -25.79390 -12.57587 1.000 17.90957 ? 94  GLU A N   1 
ATOM   705  C CA  . GLU A 1 94  ? -2.14045  -26.77387 -12.35148 1.000 24.81739 ? 94  GLU A CA  1 
ATOM   706  C C   . GLU A 1 94  ? -2.70352  -28.18951 -12.38777 1.000 20.83082 ? 94  GLU A C   1 
ATOM   707  O O   . GLU A 1 94  ? -2.59356  -28.96538 -11.43505 1.000 23.42202 ? 94  GLU A O   1 
ATOM   708  C CB  . GLU A 1 94  ? -1.42262  -26.49676 -11.02901 1.000 25.58635 ? 94  GLU A CB  1 
ATOM   709  C CG  . GLU A 1 94  ? -0.87203  -25.10121 -10.95045 1.000 26.54584 ? 94  GLU A CG  1 
ATOM   710  C CD  . GLU A 1 94  ? -0.18935  -24.81574 -9.62869  1.000 37.48260 ? 94  GLU A CD  1 
ATOM   711  O OE1 . GLU A 1 94  ? 1.05485   -24.69948 -9.63058  1.000 41.50744 ? 94  GLU A OE1 1 
ATOM   712  O OE2 . GLU A 1 94  ? -0.89389  -24.68218 -8.60265  1.000 37.74053 ? 94  GLU A OE2 1 
ATOM   713  N N   . ILE A 1 95  ? -3.32135  -28.52204 -13.51641 1.000 21.72644 ? 95  ILE A N   1 
ATOM   714  C CA  . ILE A 1 95  ? -3.97041  -29.81122 -13.66875 1.000 19.40933 ? 95  ILE A CA  1 
ATOM   715  C C   . ILE A 1 95  ? -3.57080  -30.36886 -15.02595 1.000 18.50233 ? 95  ILE A C   1 
ATOM   716  O O   . ILE A 1 95  ? -3.43058  -29.62140 -16.00183 1.000 19.76995 ? 95  ILE A O   1 
ATOM   717  C CB  . ILE A 1 95  ? -5.50044  -29.68118 -13.52061 1.000 19.11972 ? 95  ILE A CB  1 
ATOM   718  C CG1 . ILE A 1 95  ? -6.19387  -31.00836 -13.75202 1.000 24.58205 ? 95  ILE A CG1 1 
ATOM   719  C CG2 . ILE A 1 95  ? -6.06352  -28.70954 -14.54592 1.000 22.09469 ? 95  ILE A CG2 1 
ATOM   720  C CD1 . ILE A 1 95  ? -7.57949  -31.02356 -13.15916 1.000 24.03290 ? 95  ILE A CD1 1 
ATOM   721  N N   . ASP A 1 96  ? -3.33948  -31.67571 -15.07855 1.000 18.17713 ? 96  ASP A N   1 
ATOM   722  C CA  . ASP A 1 96  ? -2.94968  -32.30332 -16.33207 1.000 18.44885 ? 96  ASP A CA  1 
ATOM   723  C C   . ASP A 1 96  ? -4.08401  -32.20372 -17.34338 1.000 16.25647 ? 96  ASP A C   1 
ATOM   724  O O   . ASP A 1 96  ? -5.25865  -32.33019 -16.99140 1.000 17.99715 ? 96  ASP A O   1 
ATOM   725  C CB  . ASP A 1 96  ? -2.58255  -33.76574 -16.09515 1.000 24.14468 ? 96  ASP A CB  1 
ATOM   726  C CG  . ASP A 1 96  ? -2.06983  -34.45132 -17.34814 1.000 26.76201 ? 96  ASP A CG  1 
ATOM   727  O OD1 . ASP A 1 96  ? -2.88648  -34.91080 -18.17901 1.000 28.65828 ? 96  ASP A OD1 1 
ATOM   728  O OD2 . ASP A 1 96  ? -0.83520  -34.53026 -17.50941 1.000 41.38095 ? 96  ASP A OD2 1 
ATOM   729  N N   . ARG A 1 97  ? -3.72285  -31.98564 -18.61014 1.000 17.47893 ? 97  ARG A N   1 
ATOM   730  C CA  . ARG A 1 97  ? -4.73473  -31.84038 -19.66094 1.000 15.87382 ? 97  ARG A CA  1 
ATOM   731  C C   . ARG A 1 97  ? -5.64865  -33.05169 -19.75453 1.000 18.35226 ? 97  ARG A C   1 
ATOM   732  O O   . ARG A 1 97  ? -6.79974  -32.91474 -20.18187 1.000 16.25945 ? 97  ARG A O   1 
ATOM   733  C CB  . ARG A 1 97  ? -4.06270  -31.61216 -21.02239 1.000 23.38241 ? 97  ARG A CB  1 
ATOM   734  C CG  . ARG A 1 97  ? -3.10217  -30.44559 -21.07477 1.000 28.06780 ? 97  ARG A CG  1 
ATOM   735  C CD  . ARG A 1 97  ? -2.69061  -30.09794 -22.51381 1.000 33.97026 ? 97  ARG A CD  1 
ATOM   736  N NE  . ARG A 1 97  ? -2.07981  -28.77649 -22.64630 1.000 37.27774 ? 97  ARG A NE  1 
ATOM   737  C CZ  . ARG A 1 97  ? -1.06959  -28.30234 -21.91978 1.000 38.53863 ? 97  ARG A CZ  1 
ATOM   738  N NH1 . ARG A 1 97  ? -0.45579  -29.04001 -21.00445 1.000 40.55475 ? 97  ARG A NH1 1 
ATOM   739  N NH2 . ARG A 1 97  ? -0.65389  -27.05310 -22.12589 1.000 37.41611 ? 97  ARG A NH2 1 
ATOM   740  N N   . LYS A 1 98  ? -5.16561  -34.25027 -19.38638 1.000 17.23761 ? 98  LYS A N   1 
ATOM   741  C CA  . LYS A 1 98  ? -6.02002  -35.42566 -19.53263 1.000 16.00480 ? 98  LYS A CA  1 
ATOM   742  C C   . LYS A 1 98  ? -7.19985  -35.40939 -18.56576 1.000 14.67868 ? 98  LYS A C   1 
ATOM   743  O O   . LYS A 1 98  ? -8.12996  -36.20420 -18.73387 1.000 18.27935 ? 98  LYS A O   1 
ATOM   744  C CB  . LYS A 1 98  ? -5.23653  -36.73448 -19.33620 1.000 21.25418 ? 98  LYS A CB  1 
ATOM   745  C CG  . LYS A 1 98  ? -4.07909  -36.96178 -20.30075 1.000 32.56957 ? 98  LYS A CG  1 
ATOM   746  C CD  . LYS A 1 98  ? -3.55838  -38.42150 -20.22343 1.000 27.95554 ? 98  LYS A CD  1 
ATOM   747  C CE  . LYS A 1 98  ? -2.49772  -38.59672 -19.13243 1.000 30.06761 ? 98  LYS A CE  1 
ATOM   748  N NZ  . LYS A 1 98  ? -1.83081  -37.32267 -18.75930 1.000 39.58959 ? 98  LYS A NZ  1 
ATOM   749  N N   . HIS A 1 99  ? -7.19776  -34.51680 -17.57966 1.000 14.12021 ? 99  HIS A N   1 
ATOM   750  C CA  . HIS A 1 99  ? -8.30218  -34.40197 -16.64455 1.000 14.50355 ? 99  HIS A CA  1 
ATOM   751  C C   . HIS A 1 99  ? -9.37476  -33.42351 -17.09968 1.000 16.45582 ? 99  HIS A C   1 
ATOM   752  O O   . HIS A 1 99  ? -10.33978 -33.21213 -16.35651 1.000 17.98091 ? 99  HIS A O   1 
ATOM   753  C CB  . HIS A 1 99  ? -7.80016  -33.94327 -15.27372 1.000 17.15070 ? 99  HIS A CB  1 
ATOM   754  C CG  . HIS A 1 99  ? -6.97870  -34.95689 -14.54237 1.000 22.86853 ? 99  HIS A CG  1 
ATOM   755  N ND1 . HIS A 1 99  ? -7.44962  -36.20976 -14.21932 1.000 27.72851 ? 99  HIS A ND1 1 
ATOM   756  C CD2 . HIS A 1 99  ? -5.74300  -34.86821 -13.99783 1.000 26.79154 ? 99  HIS A CD2 1 
ATOM   757  C CE1 . HIS A 1 99  ? -6.52521  -36.86490 -13.53845 1.000 29.75928 ? 99  HIS A CE1 1 
ATOM   758  N NE2 . HIS A 1 99  ? -5.47713  -36.07523 -13.39636 1.000 29.35892 ? 99  HIS A NE2 1 
ATOM   759  N N   . ILE A 1 100 ? -9.21530  -32.79078 -18.26258 1.000 14.15870 ? 100 ILE A N   1 
ATOM   760  C CA  . ILE A 1 100 ? -10.02144 -31.63283 -18.65239 1.000 13.50534 ? 100 ILE A CA  1 
ATOM   761  C C   . ILE A 1 100 ? -10.97810 -32.01917 -19.77118 1.000 12.61715 ? 100 ILE A C   1 
ATOM   762  O O   . ILE A 1 100 ? -10.55501 -32.51646 -20.82255 1.000 14.94353 ? 100 ILE A O   1 
ATOM   763  C CB  . ILE A 1 100 ? -9.13651  -30.45006 -19.08507 1.000 14.49464 ? 100 ILE A CB  1 
ATOM   764  C CG1 . ILE A 1 100 ? -8.19581  -30.04144 -17.94246 1.000 13.78302 ? 100 ILE A CG1 1 
ATOM   765  C CG2 . ILE A 1 100 ? -10.00474 -29.27506 -19.54258 1.000 15.61821 ? 100 ILE A CG2 1 
ATOM   766  C CD1 . ILE A 1 100 ? -7.25285  -28.89802 -18.30801 1.000 17.46857 ? 100 ILE A CD1 1 
ATOM   767  N N   . TRP A 1 101 ? -12.26154 -31.72948 -19.56268 1.000 10.19037 ? 101 TRP A N   1 
ATOM   768  C CA  . TRP A 1 101 ? -13.31941 -31.96323 -20.53604 1.000 11.82814 ? 101 TRP A CA  1 
ATOM   769  C C   . TRP A 1 101 ? -13.95156 -30.61453 -20.83788 1.000 11.15588 ? 101 TRP A C   1 
ATOM   770  O O   . TRP A 1 101 ? -14.16229 -29.81512 -19.92282 1.000 10.23437 ? 101 TRP A O   1 
ATOM   771  C CB  . TRP A 1 101 ? -14.38667 -32.92224 -19.99323 1.000 13.44529 ? 101 TRP A CB  1 
ATOM   772  C CG  . TRP A 1 101 ? -13.92788 -34.31854 -19.71201 1.000 11.71684 ? 101 TRP A CG  1 
ATOM   773  C CD1 . TRP A 1 101 ? -12.69934 -34.72944 -19.20664 1.000 14.55922 ? 101 TRP A CD1 1 
ATOM   774  C CD2 . TRP A 1 101 ? -14.68479 -35.49880 -19.92178 1.000 12.05440 ? 101 TRP A CD2 1 
ATOM   775  N NE1 . TRP A 1 101 ? -12.67334 -36.10566 -19.10076 1.000 17.42034 ? 101 TRP A NE1 1 
ATOM   776  C CE2 . TRP A 1 101 ? -13.88210 -36.59905 -19.52947 1.000 13.36296 ? 101 TRP A CE2 1 
ATOM   777  C CE3 . TRP A 1 101 ? -15.97768 -35.74234 -20.38351 1.000 11.97140 ? 101 TRP A CE3 1 
ATOM   778  C CZ2 . TRP A 1 101 ? -14.34090 -37.91280 -19.59987 1.000 16.93309 ? 101 TRP A CZ2 1 
ATOM   779  C CZ3 . TRP A 1 101 ? -16.42517 -37.04297 -20.45019 1.000 9.19845  ? 101 TRP A CZ3 1 
ATOM   780  C CH2 . TRP A 1 101 ? -15.60808 -38.11279 -20.07758 1.000 12.63713 ? 101 TRP A CH2 1 
ATOM   781  N N   . VAL A 1 102 ? -14.22708 -30.34383 -22.11607 1.000 10.88740 ? 102 VAL A N   1 
ATOM   782  C CA  . VAL A 1 102 ? -14.73926 -29.03897 -22.53950 1.000 11.84677 ? 102 VAL A CA  1 
ATOM   783  C C   . VAL A 1 102 ? -15.79701 -29.28788 -23.60234 1.000 10.59039 ? 102 VAL A C   1 
ATOM   784  O O   . VAL A 1 102 ? -15.49194 -29.86896 -24.65110 1.000 10.65971 ? 102 VAL A O   1 
ATOM   785  C CB  . VAL A 1 102 ? -13.64262 -28.11284 -23.10790 1.000 13.41516 ? 102 VAL A CB  1 
ATOM   786  C CG1 . VAL A 1 102 ? -14.23225 -26.77461 -23.49741 1.000 11.74644 ? 102 VAL A CG1 1 
ATOM   787  C CG2 . VAL A 1 102 ? -12.49766 -27.92585 -22.12858 1.000 12.97020 ? 102 VAL A CG2 1 
ATOM   788  N N   . TYR A 1 103 ? -17.03206 -28.83894 -23.34550 1.000 9.50178  ? 103 TYR A N   1 
ATOM   789  C CA  . TYR A 1 103 ? -18.13768 -28.93335 -24.31076 1.000 10.93028 ? 103 TYR A CA  1 
ATOM   790  C C   . TYR A 1 103 ? -18.67756 -27.53730 -24.58492 1.000 8.82510  ? 103 TYR A C   1 
ATOM   791  O O   . TYR A 1 103 ? -18.94514 -26.79749 -23.63529 1.000 11.38898 ? 103 TYR A O   1 
ATOM   792  C CB  . TYR A 1 103 ? -19.32312 -29.73741 -23.77869 1.000 9.09945  ? 103 TYR A CB  1 
ATOM   793  C CG  . TYR A 1 103 ? -19.18994 -31.23146 -23.63327 1.000 12.08187 ? 103 TYR A CG  1 
ATOM   794  C CD1 . TYR A 1 103 ? -18.01193 -31.90564 -23.94384 1.000 10.37922 ? 103 TYR A CD1 1 
ATOM   795  C CD2 . TYR A 1 103 ? -20.28188 -31.97335 -23.21127 1.000 9.30885  ? 103 TYR A CD2 1 
ATOM   796  C CE1 . TYR A 1 103 ? -17.93586 -33.29661 -23.80121 1.000 12.48603 ? 103 TYR A CE1 1 
ATOM   797  C CE2 . TYR A 1 103 ? -20.22375 -33.33454 -23.07516 1.000 12.67647 ? 103 TYR A CE2 1 
ATOM   798  C CZ  . TYR A 1 103 ? -19.04400 -33.99539 -23.35172 1.000 11.15755 ? 103 TYR A CZ  1 
ATOM   799  O OH  . TYR A 1 103 ? -19.00361 -35.37142 -23.21609 1.000 12.94327 ? 103 TYR A OH  1 
ATOM   800  N N   . PHE A 1 104 ? -18.89879 -27.19321 -25.85729 1.000 9.90910  ? 104 PHE A N   1 
ATOM   801  C CA  . PHE A 1 104 ? -19.49574 -25.90570 -26.22067 1.000 10.07834 ? 104 PHE A CA  1 
ATOM   802  C C   . PHE A 1 104 ? -20.90457 -26.12481 -26.74820 1.000 11.11057 ? 104 PHE A C   1 
ATOM   803  O O   . PHE A 1 104 ? -21.10375 -26.94537 -27.64351 1.000 9.31137  ? 104 PHE A O   1 
ATOM   804  C CB  . PHE A 1 104 ? -18.70444 -25.17438 -27.30945 1.000 10.82071 ? 104 PHE A CB  1 
ATOM   805  C CG  . PHE A 1 104 ? -17.37236 -24.63975 -26.87838 1.000 11.69164 ? 104 PHE A CG  1 
ATOM   806  C CD1 . PHE A 1 104 ? -17.02416 -24.53931 -25.53966 1.000 12.49552 ? 104 PHE A CD1 1 
ATOM   807  C CD2 . PHE A 1 104 ? -16.45885 -24.23220 -27.85103 1.000 13.76359 ? 104 PHE A CD2 1 
ATOM   808  C CE1 . PHE A 1 104 ? -15.77552 -24.05607 -25.16704 1.000 12.47746 ? 104 PHE A CE1 1 
ATOM   809  C CE2 . PHE A 1 104 ? -15.21030 -23.73180 -27.49120 1.000 13.43974 ? 104 PHE A CE2 1 
ATOM   810  C CZ  . PHE A 1 104 ? -14.87408 -23.64145 -26.14728 1.000 11.80988 ? 104 PHE A CZ  1 
ATOM   811  N N   . GLY A 1 105 ? -21.86878 -25.38196 -26.21394 1.000 11.21488 ? 105 GLY A N   1 
ATOM   812  C CA  . GLY A 1 105 ? -23.22574 -25.39378 -26.73035 1.000 17.46897 ? 105 GLY A CA  1 
ATOM   813  C C   . GLY A 1 105 ? -23.56636 -24.00593 -27.22892 1.000 12.97729 ? 105 GLY A C   1 
ATOM   814  O O   . GLY A 1 105 ? -23.07567 -23.00872 -26.69825 1.000 14.70995 ? 105 GLY A O   1 
ATOM   815  N N   . GLU A 1 106 ? -24.39535 -23.94260 -28.28044 1.000 11.23251 ? 106 GLU A N   1 
ATOM   816  C CA  . GLU A 1 106 ? -24.68218 -22.67097 -28.92917 1.000 10.80177 ? 106 GLU A CA  1 
ATOM   817  C C   . GLU A 1 106 ? -26.18273 -22.42357 -28.98593 1.000 10.90968 ? 106 GLU A C   1 
ATOM   818  O O   . GLU A 1 106 ? -26.96823 -23.36465 -29.16376 1.000 13.19157 ? 106 GLU A O   1 
ATOM   819  C CB  . GLU A 1 106 ? -24.11890 -22.61228 -30.35010 1.000 13.88016 ? 106 GLU A CB  1 
ATOM   820  C CG  . GLU A 1 106 ? -22.63613 -22.89577 -30.45926 1.000 13.95841 ? 106 GLU A CG  1 
ATOM   821  C CD  . GLU A 1 106 ? -22.30119 -23.37692 -31.84868 1.000 13.91984 ? 106 GLU A CD  1 
ATOM   822  O OE1 . GLU A 1 106 ? -22.46775 -24.58419 -32.08397 1.000 14.92530 ? 106 GLU A OE1 1 
ATOM   823  O OE2 . GLU A 1 106 ? -21.89968 -22.55987 -32.69599 1.000 15.78185 ? 106 GLU A OE2 1 
ATOM   824  N N   . MET A 1 107 ? -26.57215 -21.16529 -28.83214 1.000 8.93152  ? 107 MET A N   1 
ATOM   825  C CA  . MET A 1 107 ? -27.96262 -20.77343 -28.97986 1.000 14.67685 ? 107 MET A CA  1 
ATOM   826  C C   . MET A 1 107 ? -28.02225 -19.54269 -29.86776 1.000 13.44736 ? 107 MET A C   1 
ATOM   827  O O   . MET A 1 107 ? -27.03833 -18.81061 -29.99496 1.000 12.38736 ? 107 MET A O   1 
ATOM   828  C CB  . MET A 1 107 ? -28.64654 -20.41990 -27.65115 1.000 13.05711 ? 107 MET A CB  1 
ATOM   829  C CG  . MET A 1 107 ? -28.81330 -21.53195 -26.66087 1.000 19.57391 ? 107 MET A CG  1 
ATOM   830  S SD  . MET A 1 107 ? -28.17691 -21.02817 -25.02335 1.000 17.44951 ? 107 MET A SD  1 
ATOM   831  C CE  . MET A 1 107 ? -26.40405 -20.92492 -25.30786 1.000 11.48823 ? 107 MET A CE  1 
ATOM   832  N N   . PRO A 1 108 ? -29.16439 -19.27521 -30.48873 1.000 13.68536 ? 108 PRO A N   1 
ATOM   833  C CA  . PRO A 1 108 ? -29.33105 -17.98355 -31.17208 1.000 14.90984 ? 108 PRO A CA  1 
ATOM   834  C C   . PRO A 1 108 ? -29.14730 -16.83107 -30.19453 1.000 13.20945 ? 108 PRO A C   1 
ATOM   835  O O   . PRO A 1 108 ? -29.68025 -16.85252 -29.08551 1.000 10.71582 ? 108 PRO A O   1 
ATOM   836  C CB  . PRO A 1 108 ? -30.76835 -18.05046 -31.70453 1.000 12.00401 ? 108 PRO A CB  1 
ATOM   837  C CG  . PRO A 1 108 ? -31.04584 -19.50771 -31.84305 1.000 14.63988 ? 108 PRO A CG  1 
ATOM   838  C CD  . PRO A 1 108 ? -30.30871 -20.18206 -30.72069 1.000 13.56632 ? 108 PRO A CD  1 
ATOM   839  N N   . ALA A 1 109 ? -28.37347 -15.81919 -30.61557 1.000 11.68581 ? 109 ALA A N   1 
ATOM   840  C CA  . ALA A 1 109 ? -28.19841 -14.62198 -29.79782 1.000 13.79875 ? 109 ALA A CA  1 
ATOM   841  C C   . ALA A 1 109 ? -29.53256 -14.01010 -29.38409 1.000 13.50605 ? 109 ALA A C   1 
ATOM   842  O O   . ALA A 1 109 ? -29.63843 -13.40955 -28.30617 1.000 13.65034 ? 109 ALA A O   1 
ATOM   843  C CB  . ALA A 1 109 ? -27.35478 -13.59483 -30.56064 1.000 12.31551 ? 109 ALA A CB  1 
ATOM   844  N N   . GLN A 1 110 ? -30.55805 -14.15701 -30.22404 1.000 14.61430 ? 110 GLN A N   1 
ATOM   845  C CA  . GLN A 1 110 ? -31.89208 -13.62505 -29.94750 1.000 12.93594 ? 110 GLN A CA  1 
ATOM   846  C C   . GLN A 1 110 ? -32.55850 -14.25210 -28.73030 1.000 14.67570 ? 110 GLN A C   1 
ATOM   847  O O   . GLN A 1 110 ? -33.57215 -13.71777 -28.26337 1.000 12.80488 ? 110 GLN A O   1 
ATOM   848  C CB  . GLN A 1 110 ? -32.80114 -13.83462 -31.16561 1.000 15.87500 ? 110 GLN A CB  1 
ATOM   849  C CG  . GLN A 1 110 ? -32.31737 -13.18520 -32.45211 1.000 24.28341 ? 110 GLN A CG  1 
ATOM   850  C CD  . GLN A 1 110 ? -31.57902 -14.16485 -33.36043 1.000 26.77644 ? 110 GLN A CD  1 
ATOM   851  O OE1 . GLN A 1 110 ? -30.60905 -14.80601 -32.96031 1.000 17.16606 ? 110 GLN A OE1 1 
ATOM   852  N NE2 . GLN A 1 110 ? -32.07015 -14.30994 -34.58430 1.000 32.93325 ? 110 GLN A NE2 1 
ATOM   853  N N   . GLN A 1 111 ? -32.05658 -15.36598 -28.21009 1.000 10.22618 ? 111 GLN A N   1 
ATOM   854  C CA  . GLN A 1 111 ? -32.61314 -15.90690 -26.96941 1.000 13.81186 ? 111 GLN A CA  1 
ATOM   855  C C   . GLN A 1 111 ? -31.57054 -15.93135 -25.86263 1.000 13.31573 ? 111 GLN A C   1 
ATOM   856  O O   . GLN A 1 111 ? -31.54915 -16.84041 -25.01967 1.000 11.29525 ? 111 GLN A O   1 
ATOM   857  C CB  . GLN A 1 111 ? -33.23441 -17.29438 -27.18282 1.000 12.62369 ? 111 GLN A CB  1 
ATOM   858  C CG  . GLN A 1 111 ? -32.29545 -18.39620 -27.67377 1.000 13.71350 ? 111 GLN A CG  1 
ATOM   859  C CD  . GLN A 1 111 ? -33.04168 -19.49010 -28.43652 1.000 12.74286 ? 111 GLN A CD  1 
ATOM   860  O OE1 . GLN A 1 111 ? -33.68213 -19.22438 -29.45830 1.000 15.45281 ? 111 GLN A OE1 1 
ATOM   861  N NE2 . GLN A 1 111 ? -32.93405 -20.72955 -27.95914 1.000 12.68655 ? 111 GLN A NE2 1 
ATOM   862  N N   . MET A 1 112 ? -30.72312 -14.89223 -25.80887 1.000 12.51425 ? 112 MET A N   1 
ATOM   863  C CA  . MET A 1 112 ? -29.59179 -14.89408 -24.89325 1.000 9.69728  ? 112 MET A CA  1 
ATOM   864  C C   . MET A 1 112 ? -29.51461 -13.47888 -24.32369 1.000 9.95911  ? 112 MET A C   1 
ATOM   865  O O   . MET A 1 112 ? -29.42564 -12.50950 -25.08671 1.000 11.94138 ? 112 MET A O   1 
ATOM   866  C CB  . MET A 1 112 ? -28.34019 -15.24001 -25.70096 1.000 12.20637 ? 112 MET A CB  1 
ATOM   867  C CG  . MET A 1 112 ? -28.14964 -16.75768 -25.86720 1.000 12.85580 ? 112 MET A CG  1 
ATOM   868  S SD  . MET A 1 112 ? -26.64065 -17.18410 -26.79196 1.000 12.57961 ? 112 MET A SD  1 
ATOM   869  C CE  . MET A 1 112 ? -25.37729 -16.78762 -25.55435 1.000 11.80850 ? 112 MET A CE  1 
ATOM   870  N N   . VAL A 1 113 ? -29.57159 -13.36416 -23.00011 1.000 10.27798 ? 113 VAL A N   1 
ATOM   871  C CA  . VAL A 1 113 ? -29.64835 -12.09378 -22.29358 1.000 9.67395  ? 113 VAL A CA  1 
ATOM   872  C C   . VAL A 1 113 ? -28.47239 -12.01209 -21.33093 1.000 12.00622 ? 113 VAL A C   1 
ATOM   873  O O   . VAL A 1 113 ? -28.24163 -12.94397 -20.55312 1.000 10.90809 ? 113 VAL A O   1 
ATOM   874  C CB  . VAL A 1 113 ? -30.98494 -11.96018 -21.53482 1.000 12.37455 ? 113 VAL A CB  1 
ATOM   875  C CG1 . VAL A 1 113 ? -30.94901 -10.78428 -20.56340 1.000 14.78983 ? 113 VAL A CG1 1 
ATOM   876  C CG2 . VAL A 1 113 ? -32.15390 -11.80424 -22.52420 1.000 11.84313 ? 113 VAL A CG2 1 
ATOM   877  N N   . GLN A 1 114 ? -27.73806 -10.89864 -21.37326 1.000 11.45883 ? 114 GLN A N   1 
ATOM   878  C CA  . GLN A 1 114 ? -26.68620 -10.62719 -20.39712 1.000 13.96236 ? 114 GLN A CA  1 
ATOM   879  C C   . GLN A 1 114 ? -26.87486 -9.20013  -19.90069 1.000 11.33321 ? 114 GLN A C   1 
ATOM   880  O O   . GLN A 1 114 ? -27.19477 -8.30444  -20.68934 1.000 12.39647 ? 114 GLN A O   1 
ATOM   881  C CB  . GLN A 1 114 ? -25.26330 -10.80027 -20.99783 1.000 13.41293 ? 114 GLN A CB  1 
ATOM   882  C CG  . GLN A 1 114 ? -25.03918 -12.17257 -21.65939 1.000 11.84097 ? 114 GLN A CG  1 
ATOM   883  C CD  . GLN A 1 114 ? -23.60208 -12.46810 -22.08801 1.000 13.34531 ? 114 GLN A CD  1 
ATOM   884  O OE1 . GLN A 1 114 ? -23.29597 -13.60077 -22.45517 1.000 13.40722 ? 114 GLN A OE1 1 
ATOM   885  N NE2 . GLN A 1 114 ? -22.70223 -11.49062 -21.95161 1.000 13.07315 ? 114 GLN A NE2 1 
ATOM   886  N N   . TYR A 1 115 ? -26.68390 -8.98248  -18.59690 1.000 13.33891 ? 115 TYR A N   1 
ATOM   887  C CA  . TYR A 1 115 ? -26.88031 -7.65610  -18.01653 1.000 12.01341 ? 115 TYR A CA  1 
ATOM   888  C C   . TYR A 1 115 ? -28.28273 -7.13335  -18.33425 1.000 12.87168 ? 115 TYR A C   1 
ATOM   889  O O   . TYR A 1 115 ? -28.48643 -5.93644  -18.53583 1.000 14.01150 ? 115 TYR A O   1 
ATOM   890  C CB  . TYR A 1 115 ? -25.80445 -6.66691  -18.50708 1.000 15.86783 ? 115 TYR A CB  1 
ATOM   891  C CG  . TYR A 1 115 ? -24.35086 -6.99559  -18.11553 1.000 16.74463 ? 115 TYR A CG  1 
ATOM   892  C CD1 . TYR A 1 115 ? -23.84261 -6.63579  -16.87283 1.000 19.82743 ? 115 TYR A CD1 1 
ATOM   893  C CD2 . TYR A 1 115 ? -23.48571 -7.63116  -19.01364 1.000 11.81503 ? 115 TYR A CD2 1 
ATOM   894  C CE1 . TYR A 1 115 ? -22.52757 -6.92322  -16.51790 1.000 17.19339 ? 115 TYR A CE1 1 
ATOM   895  C CE2 . TYR A 1 115 ? -22.17409 -7.91851  -18.67258 1.000 17.51116 ? 115 TYR A CE2 1 
ATOM   896  C CZ  . TYR A 1 115 ? -21.69598 -7.55672  -17.42469 1.000 20.28824 ? 115 TYR A CZ  1 
ATOM   897  O OH  . TYR A 1 115 ? -20.38878 -7.83556  -17.07600 1.000 17.14709 ? 115 TYR A OH  1 
ATOM   898  N N   . GLY A 1 116 ? -29.25622 -8.03608  -18.43073 1.000 15.50783 ? 116 GLY A N   1 
ATOM   899  C CA  . GLY A 1 116 ? -30.62160 -7.62832  -18.70839 1.000 15.02169 ? 116 GLY A CA  1 
ATOM   900  C C   . GLY A 1 116 ? -30.92001 -7.21886  -20.13403 1.000 15.12017 ? 116 GLY A C   1 
ATOM   901  O O   . GLY A 1 116 ? -32.01434 -6.70830  -20.38567 1.000 13.27881 ? 116 GLY A O   1 
ATOM   902  N N   . ARG A 1 117 ? -29.99917 -7.43354  -21.08442 1.000 14.28403 ? 117 ARG A N   1 
ATOM   903  C CA  . ARG A 1 117 ? -30.19109 -7.02238  -22.47113 1.000 13.68276 ? 117 ARG A CA  1 
ATOM   904  C C   . ARG A 1 117 ? -29.88210 -8.17661  -23.41708 1.000 11.85321 ? 117 ARG A C   1 
ATOM   905  O O   . ARG A 1 117 ? -29.00459 -8.99828  -23.15585 1.000 11.56551 ? 117 ARG A O   1 
ATOM   906  C CB  . ARG A 1 117 ? -29.29636 -5.83845  -22.85320 1.000 11.50191 ? 117 ARG A CB  1 
ATOM   907  C CG  . ARG A 1 117 ? -29.43818 -4.65084  -21.92274 1.000 13.17169 ? 117 ARG A CG  1 
ATOM   908  C CD  . ARG A 1 117 ? -30.68705 -3.88389  -22.23346 1.000 21.54265 ? 117 ARG A CD  1 
ATOM   909  N NE  . ARG A 1 117 ? -30.75406 -3.50156  -23.63865 1.000 24.91444 ? 117 ARG A NE  1 
ATOM   910  C CZ  . ARG A 1 117 ? -30.55192 -2.26871  -24.08518 1.000 29.27477 ? 117 ARG A CZ  1 
ATOM   911  N NH1 . ARG A 1 117 ? -30.14752 -1.30088  -23.27750 1.000 30.03250 ? 117 ARG A NH1 1 
ATOM   912  N NH2 . ARG A 1 117 ? -30.74644 -2.00327  -25.37577 1.000 28.43591 ? 117 ARG A NH2 1 
ATOM   913  N N   . PHE A 1 118 ? -30.59053 -8.21233  -24.53770 1.000 12.31379 ? 118 PHE A N   1 
ATOM   914  C CA  . PHE A 1 118 ? -30.34559 -9.25005  -25.53511 1.000 13.42987 ? 118 PHE A CA  1 
ATOM   915  C C   . PHE A 1 118 ? -29.01659 -9.02023  -26.23744 1.000 13.52647 ? 118 PHE A C   1 
ATOM   916  O O   . PHE A 1 118 ? -28.63121 -7.88488  -26.52013 1.000 12.08995 ? 118 PHE A O   1 
ATOM   917  C CB  . PHE A 1 118 ? -31.48863 -9.28011  -26.54855 1.000 13.85158 ? 118 PHE A CB  1 
ATOM   918  C CG  . PHE A 1 118 ? -32.73873 -9.85912  -25.98119 1.000 10.86249 ? 118 PHE A CG  1 
ATOM   919  C CD1 . PHE A 1 118 ? -33.63963 -9.05675  -25.30603 1.000 15.33839 ? 118 PHE A CD1 1 
ATOM   920  C CD2 . PHE A 1 118 ? -32.99007 -11.21681 -26.07920 1.000 12.62108 ? 118 PHE A CD2 1 
ATOM   921  C CE1 . PHE A 1 118 ? -34.78323 -9.58464  -24.75770 1.000 18.27930 ? 118 PHE A CE1 1 
ATOM   922  C CE2 . PHE A 1 118 ? -34.15148 -11.76580 -25.53492 1.000 15.21679 ? 118 PHE A CE2 1 
ATOM   923  C CZ  . PHE A 1 118 ? -35.04740 -10.94274 -24.87238 1.000 15.18004 ? 118 PHE A CZ  1 
ATOM   924  N N   . LEU A 1 119 ? -28.31602 -10.10345 -26.51515 1.000 12.12988 ? 119 LEU A N   1 
ATOM   925  C CA  . LEU A 1 119 ? -26.99623 -10.00396 -27.11793 1.000 13.12996 ? 119 LEU A CA  1 
ATOM   926  C C   . LEU A 1 119 ? -27.09254 -9.70054  -28.61052 1.000 16.77941 ? 119 LEU A C   1 
ATOM   927  O O   . LEU A 1 119 ? -28.11024 -9.98275  -29.25324 1.000 15.36572 ? 119 LEU A O   1 
ATOM   928  C CB  . LEU A 1 119 ? -26.22217 -11.31187 -26.89974 1.000 13.61394 ? 119 LEU A CB  1 
ATOM   929  C CG  . LEU A 1 119 ? -25.68607 -11.60653 -25.49839 1.000 14.64026 ? 119 LEU A CG  1 
ATOM   930  C CD1 . LEU A 1 119 ? -24.91137 -12.93298 -25.50446 1.000 12.17290 ? 119 LEU A CD1 1 
ATOM   931  C CD2 . LEU A 1 119 ? -24.79327 -10.45817 -25.02708 1.000 14.39400 ? 119 LEU A CD2 1 
ATOM   932  N N   . PRO A 1 120 ? -26.04382 -9.12954  -29.19037 1.000 12.73429 ? 120 PRO A N   1 
ATOM   933  C CA  . PRO A 1 120 ? -25.97685 -8.96913  -30.64634 1.000 14.50989 ? 120 PRO A CA  1 
ATOM   934  C C   . PRO A 1 120 ? -25.42162 -10.22902 -31.29520 1.000 13.41336 ? 120 PRO A C   1 
ATOM   935  O O   . PRO A 1 120 ? -24.99348 -11.16229 -30.63021 1.000 17.64838 ? 120 PRO A O   1 
ATOM   936  C CB  . PRO A 1 120 ? -24.98130 -7.83053  -30.82832 1.000 15.68379 ? 120 PRO A CB  1 
ATOM   937  C CG  . PRO A 1 120 ? -24.08820 -7.91895  -29.61949 1.000 16.48411 ? 120 PRO A CG  1 
ATOM   938  C CD  . PRO A 1 120 ? -24.75997 -8.77833  -28.55898 1.000 13.85447 ? 120 PRO A CD  1 
ATOM   939  N N   . GLN A 1 121 ? -25.37191 -10.21989 -32.62087 1.000 17.98129 ? 121 GLN A N   1 
ATOM   940  C CA  . GLN A 1 121 ? -24.71013 -11.32881 -33.29594 1.000 17.65517 ? 121 GLN A CA  1 
ATOM   941  C C   . GLN A 1 121 ? -23.18642 -11.25429 -33.13311 1.000 18.52934 ? 121 GLN A C   1 
ATOM   942  O O   . GLN A 1 121 ? -22.61716 -10.17372 -32.94426 1.000 18.14440 ? 121 GLN A O   1 
ATOM   943  C CB  . GLN A 1 121 ? -25.10551 -11.37736 -34.76789 1.000 24.51235 ? 121 GLN A CB  1 
ATOM   944  C CG  . GLN A 1 121 ? -26.60530 -11.39147 -34.92626 1.000 25.05254 ? 121 GLN A CG  1 
ATOM   945  C CD  . GLN A 1 121 ? -27.20835 -12.74105 -34.54428 1.000 24.83061 ? 121 GLN A CD  1 
ATOM   946  O OE1 . GLN A 1 121 ? -26.50944 -13.75903 -34.48473 1.000 23.89422 ? 121 GLN A OE1 1 
ATOM   947  N NE2 . GLN A 1 121 ? -28.50934 -12.75124 -34.26379 1.000 30.54696 ? 121 GLN A NE2 1 
ATOM   948  N N   . PRO A 1 122 ? -22.51378 -12.40418 -33.19032 1.000 16.47652 ? 122 PRO A N   1 
ATOM   949  C CA  . PRO A 1 122 ? -21.09354 -12.50392 -32.81004 1.000 21.53258 ? 122 PRO A CA  1 
ATOM   950  C C   . PRO A 1 122 ? -20.04370 -11.53130 -33.32813 1.000 31.35275 ? 122 PRO A C   1 
ATOM   951  O O   . PRO A 1 122 ? -18.91202 -11.60345 -32.84425 1.000 42.19411 ? 122 PRO A O   1 
ATOM   952  C CB  . PRO A 1 122 ? -20.74931 -13.92167 -33.27039 1.000 20.50970 ? 122 PRO A CB  1 
ATOM   953  C CG  . PRO A 1 122 ? -21.96761 -14.67272 -32.92557 1.000 18.34510 ? 122 PRO A CG  1 
ATOM   954  C CD  . PRO A 1 122 ? -23.10940 -13.74353 -33.33007 1.000 16.52075 ? 122 PRO A CD  1 
ATOM   955  N N   . GLY A 1 123 ? -20.31496 -10.64839 -34.26490 1.000 32.78806 ? 123 GLY A N   1 
ATOM   956  C CA  . GLY A 1 123 ? -19.22485 -9.73677  -34.57906 1.000 29.68177 ? 123 GLY A CA  1 
ATOM   957  C C   . GLY A 1 123 ? -19.53305 -8.28758  -34.28367 1.000 28.31027 ? 123 GLY A C   1 
ATOM   958  O O   . GLY A 1 123 ? -18.74706 -7.39087  -34.60826 1.000 25.92144 ? 123 GLY A O   1 
ATOM   959  N N   . HIS A 1 124 ? -20.67539 -8.05514  -33.64319 1.000 20.39745 ? 124 HIS A N   1 
ATOM   960  C CA  . HIS A 1 124 ? -21.28158 -6.73347  -33.55998 1.000 25.08807 ? 124 HIS A CA  1 
ATOM   961  C C   . HIS A 1 124 ? -21.28680 -6.18911  -32.14087 1.000 19.74041 ? 124 HIS A C   1 
ATOM   962  O O   . HIS A 1 124 ? -22.12534 -5.34717  -31.81753 1.000 20.20822 ? 124 HIS A O   1 
ATOM   963  C CB  . HIS A 1 124 ? -22.71835 -6.76536  -34.09070 1.000 22.00032 ? 124 HIS A CB  1 
ATOM   964  C CG  . HIS A 1 124 ? -22.82777 -7.10967  -35.54351 1.000 32.36333 ? 124 HIS A CG  1 
ATOM   965  N ND1 . HIS A 1 124 ? -22.25945 -8.24075  -36.09048 1.000 33.55420 ? 124 HIS A ND1 1 
ATOM   966  C CD2 . HIS A 1 124 ? -23.42793 -6.45826  -36.56683 1.000 31.49088 ? 124 HIS A CD2 1 
ATOM   967  C CE1 . HIS A 1 124 ? -22.50920 -8.27394  -37.38713 1.000 33.18701 ? 124 HIS A CE1 1 
ATOM   968  N NE2 . HIS A 1 124 ? -23.22162 -7.20620  -37.70072 1.000 38.70374 ? 124 HIS A NE2 1 
ATOM   969  N N   . GLU A 1 125 ? -20.36933 -6.66160  -31.28996 1.000 17.65868 ? 125 GLU A N   1 
ATOM   970  C CA  . GLU A 1 125 ? -20.36334 -6.25617  -29.89108 1.000 18.91088 ? 125 GLU A CA  1 
ATOM   971  C C   . GLU A 1 125 ? -19.99184 -4.78877  -29.71567 1.000 20.29948 ? 125 GLU A C   1 
ATOM   972  O O   . GLU A 1 125 ? -20.46270 -4.14614  -28.77152 1.000 18.10696 ? 125 GLU A O   1 
ATOM   973  C CB  . GLU A 1 125 ? -19.39934 -7.13523  -29.10134 1.000 17.05577 ? 125 GLU A CB  1 
ATOM   974  C CG  . GLU A 1 125 ? -19.77396 -8.60555  -29.08991 1.000 17.68200 ? 125 GLU A CG  1 
ATOM   975  C CD  . GLU A 1 125 ? -19.27322 -9.33835  -30.31410 1.000 20.33268 ? 125 GLU A CD  1 
ATOM   976  O OE1 . GLU A 1 125 ? -18.46176 -8.76488  -31.08396 1.000 17.86727 ? 125 GLU A OE1 1 
ATOM   977  O OE2 . GLU A 1 125 ? -19.70084 -10.47932 -30.51188 1.000 17.92677 ? 125 GLU A OE2 1 
ATOM   978  N N   . GLY A 1 126 ? -19.13345 -4.25463  -30.58295 1.000 18.99524 ? 126 GLY A N   1 
ATOM   979  C CA  . GLY A 1 126 ? -18.72037 -2.86844  -30.49041 1.000 23.13464 ? 126 GLY A CA  1 
ATOM   980  C C   . GLY A 1 126 ? -19.86076 -1.87432  -30.60801 1.000 21.25803 ? 126 GLY A C   1 
ATOM   981  O O   . GLY A 1 126 ? -20.06838 -1.06176  -29.69884 1.000 23.58741 ? 126 GLY A O   1 
ATOM   982  N N   . GLU A 1 127 ? -20.63217 -1.94335  -31.69452 1.000 22.47933 ? 127 GLU A N   1 
ATOM   983  C CA  . GLU A 1 127 ? -21.73300 -0.99657  -31.84927 1.000 25.46499 ? 127 GLU A CA  1 
ATOM   984  C C   . GLU A 1 127 ? -22.85387 -1.27570  -30.85485 1.000 24.14816 ? 127 GLU A C   1 
ATOM   985  O O   . GLU A 1 127 ? -23.53122 -0.34259  -30.41202 1.000 21.32797 ? 127 GLU A O   1 
ATOM   986  C CB  . GLU A 1 127 ? -22.28591 -1.01430  -33.27920 1.000 27.03757 ? 127 GLU A CB  1 
ATOM   987  C CG  . GLU A 1 127 ? -23.08173 -2.24298  -33.67416 1.000 35.09760 ? 127 GLU A CG  1 
ATOM   988  C CD  . GLU A 1 127 ? -23.04129 -2.52573  -35.17062 1.000 46.33052 ? 127 GLU A CD  1 
ATOM   989  O OE1 . GLU A 1 127 ? -23.43929 -1.63673  -35.95510 1.000 52.77559 ? 127 GLU A OE1 1 
ATOM   990  O OE2 . GLU A 1 127 ? -22.64999 -3.64607  -35.56265 1.000 46.97712 ? 127 GLU A OE2 1 
ATOM   991  N N   . TRP A 1 128 ? -23.06517 -2.54638  -30.50025 1.000 20.31748 ? 128 TRP A N   1 
ATOM   992  C CA  . TRP A 1 128 ? -24.07870 -2.89613  -29.50307 1.000 16.60052 ? 128 TRP A CA  1 
ATOM   993  C C   . TRP A 1 128 ? -23.79275 -2.21412  -28.17460 1.000 15.44824 ? 128 TRP A C   1 
ATOM   994  O O   . TRP A 1 128 ? -24.68953 -1.63435  -27.54793 1.000 16.84894 ? 128 TRP A O   1 
ATOM   995  C CB  . TRP A 1 128 ? -24.10414 -4.41815  -29.33471 1.000 16.25798 ? 128 TRP A CB  1 
ATOM   996  C CG  . TRP A 1 128 ? -24.97877 -4.96470  -28.23459 1.000 17.84481 ? 128 TRP A CG  1 
ATOM   997  C CD1 . TRP A 1 128 ? -26.30408 -5.24683  -28.32273 1.000 20.28564 ? 128 TRP A CD1 1 
ATOM   998  C CD2 . TRP A 1 128 ? -24.57460 -5.34207  -26.90906 1.000 17.22575 ? 128 TRP A CD2 1 
ATOM   999  N NE1 . TRP A 1 128 ? -26.75756 -5.77110  -27.13341 1.000 17.61670 ? 128 TRP A NE1 1 
ATOM   1000 C CE2 . TRP A 1 128 ? -25.71622 -5.83043  -26.24779 1.000 15.50531 ? 128 TRP A CE2 1 
ATOM   1001 C CE3 . TRP A 1 128 ? -23.35988 -5.30455  -26.21588 1.000 18.29696 ? 128 TRP A CE3 1 
ATOM   1002 C CZ2 . TRP A 1 128 ? -25.68229 -6.28592  -24.92226 1.000 14.96908 ? 128 TRP A CZ2 1 
ATOM   1003 C CZ3 . TRP A 1 128 ? -23.32513 -5.75330  -24.89536 1.000 19.32248 ? 128 TRP A CZ3 1 
ATOM   1004 C CH2 . TRP A 1 128 ? -24.48166 -6.23949  -24.26291 1.000 16.49887 ? 128 TRP A CH2 1 
ATOM   1005 N N   . PHE A 1 129 ? -22.53856 -2.29791  -27.71976 1.000 13.91079 ? 129 PHE A N   1 
ATOM   1006 C CA  . PHE A 1 129 ? -22.15520 -1.70904  -26.45004 1.000 15.24175 ? 129 PHE A CA  1 
ATOM   1007 C C   . PHE A 1 129 ? -22.27756 -0.19882  -26.51610 1.000 15.50353 ? 129 PHE A C   1 
ATOM   1008 O O   . PHE A 1 129 ? -22.68896 0.44069   -25.54488 1.000 16.99537 ? 129 PHE A O   1 
ATOM   1009 C CB  . PHE A 1 129 ? -20.72351 -2.11909  -26.10659 1.000 17.20771 ? 129 PHE A CB  1 
ATOM   1010 C CG  . PHE A 1 129 ? -20.15599 -1.43259  -24.89532 1.000 18.18923 ? 129 PHE A CG  1 
ATOM   1011 C CD1 . PHE A 1 129 ? -20.50192 -1.85479  -23.61596 1.000 19.37290 ? 129 PHE A CD1 1 
ATOM   1012 C CD2 . PHE A 1 129 ? -19.27433 -0.36172  -25.03414 1.000 21.88440 ? 129 PHE A CD2 1 
ATOM   1013 C CE1 . PHE A 1 129 ? -19.97078 -1.23147  -22.49563 1.000 21.79729 ? 129 PHE A CE1 1 
ATOM   1014 C CE2 . PHE A 1 129 ? -18.73290 0.27316   -23.91545 1.000 22.44136 ? 129 PHE A CE2 1 
ATOM   1015 C CZ  . PHE A 1 129 ? -19.07558 -0.16208  -22.64993 1.000 18.99379 ? 129 PHE A CZ  1 
ATOM   1016 N N   . ASP A 1 130 ? -21.92638 0.38770   -27.66366 1.000 18.28562 ? 130 ASP A N   1 
ATOM   1017 C CA  . ASP A 1 130 ? -21.94412 1.84067   -27.78915 1.000 19.55414 ? 130 ASP A CA  1 
ATOM   1018 C C   . ASP A 1 130 ? -23.35851 2.39284   -27.65588 1.000 22.05426 ? 130 ASP A C   1 
ATOM   1019 O O   . ASP A 1 130 ? -23.54858 3.49286   -27.12789 1.000 23.48346 ? 130 ASP A O   1 
ATOM   1020 C CB  . ASP A 1 130 ? -21.32921 2.24073   -29.12992 1.000 22.60255 ? 130 ASP A CB  1 
ATOM   1021 C CG  . ASP A 1 130 ? -19.80992 2.13607   -29.13419 1.000 29.45034 ? 130 ASP A CG  1 
ATOM   1022 O OD1 . ASP A 1 130 ? -19.19932 1.99829   -28.04902 1.000 27.95493 ? 130 ASP A OD1 1 
ATOM   1023 O OD2 . ASP A 1 130 ? -19.22878 2.12025   -30.23857 1.000 32.80593 ? 130 ASP A OD2 1 
ATOM   1024 N N   . ASN A 1 131 ? -24.36198 1.64532   -28.11156 1.000 24.47453 ? 131 ASN A N   1 
ATOM   1025 C CA  . ASN A 1 131 ? -25.74388 2.11214   -28.06935 1.000 22.57587 ? 131 ASN A CA  1 
ATOM   1026 C C   . ASN A 1 131 ? -26.49431 1.69095   -26.80804 1.000 24.04780 ? 131 ASN A C   1 
ATOM   1027 O O   . ASN A 1 131 ? -27.70397 1.91726   -26.71757 1.000 20.34190 ? 131 ASN A O   1 
ATOM   1028 C CB  . ASN A 1 131 ? -26.49381 1.65127   -29.32012 1.000 27.96376 ? 131 ASN A CB  1 
ATOM   1029 C CG  . ASN A 1 131 ? -25.83094 2.13385   -30.59684 1.000 36.00330 ? 131 ASN A CG  1 
ATOM   1030 O OD1 . ASN A 1 131 ? -25.64435 1.36933   -31.54536 1.000 38.40077 ? 131 ASN A OD1 1 
ATOM   1031 N ND2 . ASN A 1 131 ? -25.45528 3.41277   -30.61982 1.000 35.22709 ? 131 ASN A ND2 1 
ATOM   1032 N N   . LEU A 1 132 ? -25.81154 1.10477   -25.83062 1.000 17.08965 ? 132 LEU A N   1 
ATOM   1033 C CA  . LEU A 1 132 ? -26.40477 0.92951   -24.51334 1.000 17.90746 ? 132 LEU A CA  1 
ATOM   1034 C C   . LEU A 1 132 ? -26.43999 2.27857   -23.79294 1.000 19.09915 ? 132 LEU A C   1 
ATOM   1035 O O   . LEU A 1 132 ? -25.65493 3.17851   -24.09226 1.000 16.76866 ? 132 LEU A O   1 
ATOM   1036 C CB  . LEU A 1 132 ? -25.58190 -0.08387  -23.71714 1.000 16.38947 ? 132 LEU A CB  1 
ATOM   1037 C CG  . LEU A 1 132 ? -25.54317 -1.48521  -24.33385 1.000 19.86616 ? 132 LEU A CG  1 
ATOM   1038 C CD1 . LEU A 1 132 ? -24.88794 -2.39600  -23.37362 1.000 22.50670 ? 132 LEU A CD1 1 
ATOM   1039 C CD2 . LEU A 1 132 ? -26.94891 -1.99988  -24.56459 1.000 20.66852 ? 132 LEU A CD2 1 
ATOM   1040 N N   . SER A 1 133 ? -27.37152 2.42627   -22.85277 1.000 15.70806 ? 133 SER A N   1 
ATOM   1041 C CA  . SER A 1 133 ? -27.38688 3.61879   -22.00706 1.000 17.94505 ? 133 SER A CA  1 
ATOM   1042 C C   . SER A 1 133 ? -26.05748 3.78600   -21.27346 1.000 15.30706 ? 133 SER A C   1 
ATOM   1043 O O   . SER A 1 133 ? -25.30246 2.83669   -21.06910 1.000 14.83726 ? 133 SER A O   1 
ATOM   1044 C CB  . SER A 1 133 ? -28.52046 3.54953   -20.98153 1.000 15.85931 ? 133 SER A CB  1 
ATOM   1045 O OG  . SER A 1 133 ? -28.23186 2.61669   -19.95027 1.000 16.10895 ? 133 SER A OG  1 
ATOM   1046 N N   . SER A 1 134 ? -25.77452 5.02098   -20.85127 1.000 15.68503 ? 134 SER A N   1 
ATOM   1047 C CA  . SER A 1 134 ? -24.46153 5.27861   -20.25849 1.000 12.57940 ? 134 SER A CA  1 
ATOM   1048 C C   . SER A 1 134 ? -24.30155 4.54269   -18.93216 1.000 14.72839 ? 134 SER A C   1 
ATOM   1049 O O   . SER A 1 134 ? -23.20068 4.08280   -18.59950 1.000 15.75965 ? 134 SER A O   1 
ATOM   1050 C CB  . SER A 1 134 ? -24.24993 6.78152   -20.06119 1.000 16.47959 ? 134 SER A CB  1 
ATOM   1051 O OG  . SER A 1 134 ? -25.32528 7.35176   -19.34431 1.000 24.51408 ? 134 SER A OG  1 
ATOM   1052 N N   . ASP A 1 135 ? -25.38729 4.42341   -18.15576 1.000 11.87628 ? 135 ASP A N   1 
ATOM   1053 C CA  . ASP A 1 135 ? -25.32667 3.69651   -16.89220 1.000 14.52431 ? 135 ASP A CA  1 
ATOM   1054 C C   . ASP A 1 135 ? -25.10126 2.20849   -17.11136 1.000 14.12184 ? 135 ASP A C   1 
ATOM   1055 O O   . ASP A 1 135 ? -24.47940 1.54405   -16.27345 1.000 16.89296 ? 135 ASP A O   1 
ATOM   1056 C CB  . ASP A 1 135 ? -26.61258 3.90877   -16.09452 1.000 14.45277 ? 135 ASP A CB  1 
ATOM   1057 C CG  . ASP A 1 135 ? -26.61055 5.21746   -15.33298 1.000 22.30759 ? 135 ASP A CG  1 
ATOM   1058 O OD1 . ASP A 1 135 ? -25.55087 5.87487   -15.29114 1.000 23.67038 ? 135 ASP A OD1 1 
ATOM   1059 O OD2 . ASP A 1 135 ? -27.66921 5.60316   -14.79955 1.000 25.92148 ? 135 ASP A OD2 1 
ATOM   1060 N N   . GLU A 1 136 ? -25.61415 1.66486   -18.20798 1.000 12.46773 ? 136 GLU A N   1 
ATOM   1061 C CA  . GLU A 1 136 ? -25.36393 0.25973   -18.50082 1.000 13.22115 ? 136 GLU A CA  1 
ATOM   1062 C C   . GLU A 1 136 ? -23.91530 0.04051   -18.91927 1.000 14.21892 ? 136 GLU A C   1 
ATOM   1063 O O   . GLU A 1 136 ? -23.27101 -0.91485  -18.46284 1.000 15.35487 ? 136 GLU A O   1 
ATOM   1064 C CB  . GLU A 1 136 ? -26.30739 -0.22431  -19.59099 1.000 17.29331 ? 136 GLU A CB  1 
ATOM   1065 C CG  . GLU A 1 136 ? -27.72236 -0.43309  -19.11081 1.000 17.14770 ? 136 GLU A CG  1 
ATOM   1066 C CD  . GLU A 1 136 ? -28.67513 -0.66286  -20.26454 1.000 25.93877 ? 136 GLU A CD  1 
ATOM   1067 O OE1 . GLU A 1 136 ? -29.02157 0.30787   -20.97349 1.000 21.56906 ? 136 GLU A OE1 1 
ATOM   1068 O OE2 . GLU A 1 136 ? -29.07072 -1.82392  -20.46456 1.000 21.38838 ? 136 GLU A OE2 1 
ATOM   1069 N N   . ARG A 1 137 ? -23.38646 0.90839   -19.79114 1.000 12.86560 ? 137 ARG A N   1 
ATOM   1070 C CA  . ARG A 1 137 ? -21.97142 0.81266   -20.15521 1.000 14.57225 ? 137 ARG A CA  1 
ATOM   1071 C C   . ARG A 1 137 ? -21.07732 0.93025   -18.92828 1.000 15.66362 ? 137 ARG A C   1 
ATOM   1072 O O   . ARG A 1 137 ? -20.14284 0.13509   -18.74913 1.000 15.11762 ? 137 ARG A O   1 
ATOM   1073 C CB  . ARG A 1 137 ? -21.59720 1.87159   -21.20252 1.000 14.08112 ? 137 ARG A CB  1 
ATOM   1074 C CG  . ARG A 1 137 ? -22.52065 1.95149   -22.42419 1.000 16.29190 ? 137 ARG A CG  1 
ATOM   1075 C CD  . ARG A 1 137 ? -21.79565 2.67935   -23.57285 1.000 19.53725 ? 137 ARG A CD  1 
ATOM   1076 N NE  . ARG A 1 137 ? -21.42609 4.03486   -23.17861 1.000 18.14047 ? 137 ARG A NE  1 
ATOM   1077 C CZ  . ARG A 1 137 ? -22.24538 5.07547   -23.18729 1.000 23.75708 ? 137 ARG A CZ  1 
ATOM   1078 N NH1 . ARG A 1 137 ? -23.47253 4.98763   -23.68807 1.000 20.08738 ? 137 ARG A NH1 1 
ATOM   1079 N NH2 . ARG A 1 137 ? -21.82702 6.23295   -22.67237 1.000 24.59355 ? 137 ARG A NH2 1 
ATOM   1080 N N   . ALA A 1 138 ? -21.36331 1.90269   -18.05516 1.000 17.10006 ? 138 ALA A N   1 
ATOM   1081 C CA  . ALA A 1 138 ? -20.53177 2.09872   -16.87038 1.000 17.28794 ? 138 ALA A CA  1 
ATOM   1082 C C   . ALA A 1 138 ? -20.51892 0.85648   -16.00008 1.000 15.08637 ? 138 ALA A C   1 
ATOM   1083 O O   . ALA A 1 138 ? -19.47307 0.47578   -15.46021 1.000 17.04223 ? 138 ALA A O   1 
ATOM   1084 C CB  . ALA A 1 138 ? -21.02809 3.29249   -16.05176 1.000 16.02041 ? 138 ALA A CB  1 
ATOM   1085 N N   . PHE A 1 139 ? -21.67944 0.22068   -15.84034 1.000 14.78668 ? 139 PHE A N   1 
ATOM   1086 C CA  . PHE A 1 139 ? -21.76765 -0.95412  -14.98913 1.000 16.22757 ? 139 PHE A CA  1 
ATOM   1087 C C   . PHE A 1 139 ? -20.98448 -2.12148  -15.57545 1.000 18.10562 ? 139 PHE A C   1 
ATOM   1088 O O   . PHE A 1 139 ? -20.25756 -2.80480  -14.84637 1.000 18.10154 ? 139 PHE A O   1 
ATOM   1089 C CB  . PHE A 1 139 ? -23.22640 -1.34867  -14.76829 1.000 16.51059 ? 139 PHE A CB  1 
ATOM   1090 C CG  . PHE A 1 139 ? -23.37735 -2.55515  -13.88737 1.000 18.39635 ? 139 PHE A CG  1 
ATOM   1091 C CD1 . PHE A 1 139 ? -23.17654 -2.45635  -12.52302 1.000 19.16825 ? 139 PHE A CD1 1 
ATOM   1092 C CD2 . PHE A 1 139 ? -23.68291 -3.79238  -14.42911 1.000 16.41944 ? 139 PHE A CD2 1 
ATOM   1093 C CE1 . PHE A 1 139 ? -23.29711 -3.57266  -11.70038 1.000 22.19379 ? 139 PHE A CE1 1 
ATOM   1094 C CE2 . PHE A 1 139 ? -23.80969 -4.92332  -13.60664 1.000 18.62843 ? 139 PHE A CE2 1 
ATOM   1095 C CZ  . PHE A 1 139 ? -23.62089 -4.80232  -12.24459 1.000 23.39655 ? 139 PHE A CZ  1 
ATOM   1096 N N   . MET A 1 140 ? -21.13316 -2.38176  -16.88781 1.000 14.25461 ? 140 MET A N   1 
ATOM   1097 C CA  . MET A 1 140 ? -20.32574 -3.43171  -17.51277 1.000 14.80971 ? 140 MET A CA  1 
ATOM   1098 C C   . MET A 1 140 ? -18.83939 -3.15444  -17.38388 1.000 19.09709 ? 140 MET A C   1 
ATOM   1099 O O   . MET A 1 140 ? -18.05492 -4.07837  -17.14283 1.000 18.01367 ? 140 MET A O   1 
ATOM   1100 C CB  . MET A 1 140 ? -20.68686 -3.63194  -18.99075 1.000 19.24839 ? 140 MET A CB  1 
ATOM   1101 C CG  . MET A 1 140 ? -22.14611 -3.65363  -19.31810 1.000 24.88647 ? 140 MET A CG  1 
ATOM   1102 S SD  . MET A 1 140 ? -22.35287 -4.11068  -21.05593 1.000 20.09539 ? 140 MET A SD  1 
ATOM   1103 C CE  . MET A 1 140 ? -24.05134 -4.63577  -21.00195 1.000 20.80703 ? 140 MET A CE  1 
ATOM   1104 N N   . GLU A 1 141 ? -18.43859 -1.88729  -17.52574 1.000 20.73574 ? 141 GLU A N   1 
ATOM   1105 C CA  . GLU A 1 141 ? -17.03137 -1.51057  -17.51349 1.000 24.12238 ? 141 GLU A CA  1 
ATOM   1106 C C   . GLU A 1 141 ? -16.36293 -1.75538  -16.16322 1.000 27.08263 ? 141 GLU A C   1 
ATOM   1107 O O   . GLU A 1 141 ? -15.13457 -1.90772  -16.11693 1.000 29.43901 ? 141 GLU A O   1 
ATOM   1108 C CB  . GLU A 1 141 ? -16.91931 -0.04273  -17.90710 1.000 23.88924 ? 141 GLU A CB  1 
ATOM   1109 C CG  . GLU A 1 141 ? -17.18253 0.18368   -19.38008 1.000 25.57952 ? 141 GLU A CG  1 
ATOM   1110 C CD  . GLU A 1 141 ? -16.89119 1.60647   -19.80326 1.000 28.37365 ? 141 GLU A CD  1 
ATOM   1111 O OE1 . GLU A 1 141 ? -17.19378 2.53208   -19.01655 1.000 31.72327 ? 141 GLU A OE1 1 
ATOM   1112 O OE2 . GLU A 1 141 ? -16.38736 1.79903   -20.92516 1.000 45.61438 ? 141 GLU A OE2 1 
ATOM   1113 N N   . THR A 1 142 ? -17.13237 -1.80074  -15.06749 1.000 24.89588 ? 142 THR A N   1 
ATOM   1114 C CA  . THR A 1 142 ? -16.56715 -2.19027  -13.77473 1.000 25.78323 ? 142 THR A CA  1 
ATOM   1115 C C   . THR A 1 142 ? -16.11028 -3.64896  -13.73744 1.000 26.64210 ? 142 THR A C   1 
ATOM   1116 O O   . THR A 1 142 ? -15.40966 -4.03366  -12.79178 1.000 25.24840 ? 142 THR A O   1 
ATOM   1117 C CB  . THR A 1 142 ? -17.57366 -1.92645  -12.63950 1.000 29.40850 ? 142 THR A CB  1 
ATOM   1118 O OG1 . THR A 1 142 ? -18.49167 -3.02634  -12.50677 1.000 32.17220 ? 142 THR A OG1 1 
ATOM   1119 C CG2 . THR A 1 142 ? -18.34382 -0.62579  -12.85132 1.000 27.72189 ? 142 THR A CG2 1 
ATOM   1120 N N   . ASN A 1 143 ? -16.46002 -4.45786  -14.73728 1.000 19.20945 ? 143 ASN A N   1 
ATOM   1121 C CA  . ASN A 1 143 ? -16.10171 -5.88214  -14.74903 1.000 22.72288 ? 143 ASN A CA  1 
ATOM   1122 C C   . ASN A 1 143 ? -14.97280 -6.17342  -15.74251 1.000 22.41482 ? 143 ASN A C   1 
ATOM   1123 O O   . ASN A 1 143 ? -15.09508 -6.98796  -16.66890 1.000 22.14310 ? 143 ASN A O   1 
ATOM   1124 C CB  . ASN A 1 143 ? -17.33055 -6.72333  -15.05869 1.000 19.58773 ? 143 ASN A CB  1 
ATOM   1125 C CG  . ASN A 1 143 ? -18.28467 -6.78793  -13.89389 1.000 22.20065 ? 143 ASN A CG  1 
ATOM   1126 O OD1 . ASN A 1 143 ? -17.85863 -6.87616  -12.74086 1.000 26.40459 ? 143 ASN A OD1 1 
ATOM   1127 N ND2 . ASN A 1 143 ? -19.57786 -6.72535  -14.17607 1.000 20.48987 ? 143 ASN A ND2 1 
ATOM   1128 N N   . VAL A 1 144 ? -13.84003 -5.50643  -15.55750 1.000 24.80592 ? 144 VAL A N   1 
ATOM   1129 C CA  . VAL A 1 144 ? -12.68450 -5.73256  -16.41425 1.000 24.96774 ? 144 VAL A CA  1 
ATOM   1130 C C   . VAL A 1 144 ? -11.46929 -5.99071  -15.53238 1.000 33.32304 ? 144 VAL A C   1 
ATOM   1131 O O   . VAL A 1 144 ? -11.21338 -5.23756  -14.58867 1.000 33.03620 ? 144 VAL A O   1 
ATOM   1132 C CB  . VAL A 1 144 ? -12.44333 -4.55160  -17.37455 1.000 34.16911 ? 144 VAL A CB  1 
ATOM   1133 C CG1 . VAL A 1 144 ? -11.21069 -4.80907  -18.22570 1.000 28.37878 ? 144 VAL A CG1 1 
ATOM   1134 C CG2 . VAL A 1 144 ? -13.67856 -4.34003  -18.26983 1.000 27.39021 ? 144 VAL A CG2 1 
ATOM   1135 N N   . ASP A 1 145 ? -10.74842 -7.07200  -15.82910 1.000 34.50134 ? 145 ASP A N   1 
ATOM   1136 C CA  . ASP A 1 145 ? -9.53871  -7.48341  -15.11712 1.000 36.10138 ? 145 ASP A CA  1 
ATOM   1137 C C   . ASP A 1 145 ? -8.53898  -8.05588  -16.12364 1.000 46.98309 ? 145 ASP A C   1 
ATOM   1138 O O   . ASP A 1 145 ? -8.20685  -7.42031  -17.13309 1.000 51.68719 ? 145 ASP A O   1 
ATOM   1139 C CB  . ASP A 1 145 ? -9.88387  -8.51120  -14.03382 1.000 28.53795 ? 145 ASP A CB  1 
ATOM   1140 C CG  . ASP A 1 145 ? -8.66281  -9.06186  -13.31043 1.000 41.53467 ? 145 ASP A CG  1 
ATOM   1141 O OD1 . ASP A 1 145 ? -7.80393  -9.69756  -13.95292 1.000 39.63771 ? 145 ASP A OD1 1 
ATOM   1142 O OD2 . ASP A 1 145 ? -8.57547  -8.87522  -12.07850 1.000 43.22252 ? 145 ASP A OD2 1 
ATOM   1143 N N   . PRO B 1 1   ? -40.53436 -27.43294 -19.32179 1.000 13.71077 ? 1   PRO B N   1 
ATOM   1144 C CA  . PRO B 1 1   ? -39.16558 -26.89908 -19.26406 1.000 15.41642 ? 1   PRO B CA  1 
ATOM   1145 C C   . PRO B 1 1   ? -38.46438 -27.18115 -17.94799 1.000 13.58887 ? 1   PRO B C   1 
ATOM   1146 O O   . PRO B 1 1   ? -39.12221 -27.52845 -16.95948 1.000 12.52186 ? 1   PRO B O   1 
ATOM   1147 C CB  . PRO B 1 1   ? -39.37749 -25.39860 -19.39890 1.000 13.32161 ? 1   PRO B CB  1 
ATOM   1148 C CG  . PRO B 1 1   ? -40.69767 -25.18454 -18.70806 1.000 16.07613 ? 1   PRO B CG  1 
ATOM   1149 C CD  . PRO B 1 1   ? -41.53204 -26.36182 -19.14410 1.000 15.73463 ? 1   PRO B CD  1 
ATOM   1150 N N   . VAL B 1 2   ? -37.14397 -27.02251 -17.93019 1.000 13.01851 ? 2   VAL B N   1 
ATOM   1151 C CA  . VAL B 1 2   ? -36.37992 -26.94218 -16.69132 1.000 11.86363 ? 2   VAL B CA  1 
ATOM   1152 C C   . VAL B 1 2   ? -35.63436 -25.61973 -16.72878 1.000 14.70392 ? 2   VAL B C   1 
ATOM   1153 O O   . VAL B 1 2   ? -34.88417 -25.34964 -17.67330 1.000 13.14413 ? 2   VAL B O   1 
ATOM   1154 C CB  . VAL B 1 2   ? -35.39782 -28.11056 -16.51022 1.000 12.62549 ? 2   VAL B CB  1 
ATOM   1155 C CG1 . VAL B 1 2   ? -34.54552 -27.85668 -15.27062 1.000 12.36756 ? 2   VAL B CG1 1 
ATOM   1156 C CG2 . VAL B 1 2   ? -36.13099 -29.43608 -16.40383 1.000 11.11871 ? 2   VAL B CG2 1 
ATOM   1157 N N   . TYR B 1 3   ? -35.85341 -24.79590 -15.71875 1.000 11.30515 ? 3   TYR B N   1 
ATOM   1158 C CA  . TYR B 1 3   ? -35.13806 -23.53988 -15.54836 1.000 10.80343 ? 3   TYR B CA  1 
ATOM   1159 C C   . TYR B 1 3   ? -34.11123 -23.77642 -14.46472 1.000 13.29044 ? 3   TYR B C   1 
ATOM   1160 O O   . TYR B 1 3   ? -34.46963 -23.97792 -13.29792 1.000 12.76508 ? 3   TYR B O   1 
ATOM   1161 C CB  . TYR B 1 3   ? -36.09045 -22.41728 -15.15855 1.000 10.63621 ? 3   TYR B CB  1 
ATOM   1162 C CG  . TYR B 1 3   ? -36.93408 -21.94958 -16.30237 1.000 12.37786 ? 3   TYR B CG  1 
ATOM   1163 C CD1 . TYR B 1 3   ? -36.45099 -21.01276 -17.20689 1.000 12.54488 ? 3   TYR B CD1 1 
ATOM   1164 C CD2 . TYR B 1 3   ? -38.21309 -22.45258 -16.49369 1.000 12.24588 ? 3   TYR B CD2 1 
ATOM   1165 C CE1 . TYR B 1 3   ? -37.21932 -20.58534 -18.26798 1.000 11.42241 ? 3   TYR B CE1 1 
ATOM   1166 C CE2 . TYR B 1 3   ? -38.98954 -22.02177 -17.55889 1.000 16.22511 ? 3   TYR B CE2 1 
ATOM   1167 C CZ  . TYR B 1 3   ? -38.48324 -21.08340 -18.42797 1.000 13.78777 ? 3   TYR B CZ  1 
ATOM   1168 O OH  . TYR B 1 3   ? -39.23977 -20.63463 -19.48541 1.000 15.24667 ? 3   TYR B OH  1 
ATOM   1169 N N   . MET B 1 4   ? -32.84026 -23.76573 -14.84725 1.000 10.04919 ? 4   MET B N   1 
ATOM   1170 C CA  . MET B 1 4   ? -31.77364 -23.95156 -13.89116 1.000 12.16627 ? 4   MET B CA  1 
ATOM   1171 C C   . MET B 1 4   ? -31.41910 -22.53910 -13.43894 1.000 12.08563 ? 4   MET B C   1 
ATOM   1172 O O   . MET B 1 4   ? -31.10833 -21.69093 -14.27846 1.000 15.07630 ? 4   MET B O   1 
ATOM   1173 C CB  . MET B 1 4   ? -30.57609 -24.62116 -14.55947 1.000 12.34070 ? 4   MET B CB  1 
ATOM   1174 C CG  . MET B 1 4   ? -30.99551 -25.98367 -15.05398 1.000 14.35121 ? 4   MET B CG  1 
ATOM   1175 S SD  . MET B 1 4   ? -31.32377 -27.26142 -13.86564 1.000 15.69852 ? 4   MET B SD  1 
ATOM   1176 C CE  . MET B 1 4   ? -29.83641 -27.31780 -12.88593 1.000 12.56992 ? 4   MET B CE  1 
ATOM   1177 N N   . VAL B 1 5   ? -31.48824 -22.26029 -12.13730 1.000 12.11323 ? 5   VAL B N   1 
ATOM   1178 C CA  . VAL B 1 5   ? -31.28562 -20.89613 -11.63904 1.000 13.80535 ? 5   VAL B CA  1 
ATOM   1179 C C   . VAL B 1 5   ? -30.06692 -20.87639 -10.73224 1.000 13.02876 ? 5   VAL B C   1 
ATOM   1180 O O   . VAL B 1 5   ? -30.08600 -21.43664 -9.62926  1.000 12.04389 ? 5   VAL B O   1 
ATOM   1181 C CB  . VAL B 1 5   ? -32.52698 -20.35576 -10.91436 1.000 13.78422 ? 5   VAL B CB  1 
ATOM   1182 C CG1 . VAL B 1 5   ? -32.36054 -18.87236 -10.63985 1.000 13.00187 ? 5   VAL B CG1 1 
ATOM   1183 C CG2 . VAL B 1 5   ? -33.73643 -20.53241 -11.77796 1.000 12.92743 ? 5   VAL B CG2 1 
ATOM   1184 N N   . TYR B 1 6   ? -29.01709 -20.20302 -11.18305 1.000 10.90790 ? 6   TYR B N   1 
ATOM   1185 C CA  . TYR B 1 6   ? -27.73365 -20.18215 -10.49676 1.000 10.58962 ? 6   TYR B CA  1 
ATOM   1186 C C   . TYR B 1 6   ? -27.62717 -18.91725 -9.66303  1.000 10.73360 ? 6   TYR B C   1 
ATOM   1187 O O   . TYR B 1 6   ? -27.60359 -17.81446 -10.21477 1.000 14.22863 ? 6   TYR B O   1 
ATOM   1188 C CB  . TYR B 1 6   ? -26.59158 -20.24667 -11.51255 1.000 11.91222 ? 6   TYR B CB  1 
ATOM   1189 C CG  . TYR B 1 6   ? -26.66251 -21.52033 -12.32530 1.000 12.63885 ? 6   TYR B CG  1 
ATOM   1190 C CD1 . TYR B 1 6   ? -26.12753 -22.70694 -11.82706 1.000 10.88280 ? 6   TYR B CD1 1 
ATOM   1191 C CD2 . TYR B 1 6   ? -27.31631 -21.54693 -13.54444 1.000 11.71513 ? 6   TYR B CD2 1 
ATOM   1192 C CE1 . TYR B 1 6   ? -26.20587 -23.89740 -12.55460 1.000 14.14374 ? 6   TYR B CE1 1 
ATOM   1193 C CE2 . TYR B 1 6   ? -27.41962 -22.72342 -14.27695 1.000 12.92257 ? 6   TYR B CE2 1 
ATOM   1194 C CZ  . TYR B 1 6   ? -26.84423 -23.89389 -13.78673 1.000 12.52068 ? 6   TYR B CZ  1 
ATOM   1195 O OH  . TYR B 1 6   ? -26.93800 -25.06831 -14.50153 1.000 12.31603 ? 6   TYR B OH  1 
ATOM   1196 N N   . VAL B 1 7   ? -27.54823 -19.07470 -8.34234  1.000 15.01617 ? 7   VAL B N   1 
ATOM   1197 C CA  . VAL B 1 7   ? -27.53076 -17.94429 -7.42371  1.000 11.04247 ? 7   VAL B CA  1 
ATOM   1198 C C   . VAL B 1 7   ? -26.53254 -18.23167 -6.31591  1.000 14.71128 ? 7   VAL B C   1 
ATOM   1199 O O   . VAL B 1 7   ? -26.05296 -19.35173 -6.14565  1.000 13.75121 ? 7   VAL B O   1 
ATOM   1200 C CB  . VAL B 1 7   ? -28.91565 -17.67032 -6.80533  1.000 13.51666 ? 7   VAL B CB  1 
ATOM   1201 C CG1 . VAL B 1 7   ? -29.87534 -17.18603 -7.87042  1.000 15.47740 ? 7   VAL B CG1 1 
ATOM   1202 C CG2 . VAL B 1 7   ? -29.41470 -18.92304 -6.11731  1.000 12.80225 ? 7   VAL B CG2 1 
ATOM   1203 N N   . SER B 1 8   ? -26.20864 -17.18874 -5.56912  1.000 13.46021 ? 8   SER B N   1 
ATOM   1204 C CA  . SER B 1 8   ? -25.28563 -17.33788 -4.46340  1.000 16.28150 ? 8   SER B CA  1 
ATOM   1205 C C   . SER B 1 8   ? -26.02917 -17.85871 -3.24574  1.000 14.21743 ? 8   SER B C   1 
ATOM   1206 O O   . SER B 1 8   ? -27.19588 -17.52587 -3.02201  1.000 18.30789 ? 8   SER B O   1 
ATOM   1207 C CB  . SER B 1 8   ? -24.61505 -16.00472 -4.14071  1.000 19.85188 ? 8   SER B CB  1 
ATOM   1208 O OG  . SER B 1 8   ? -23.73862 -15.62862 -5.19395  1.000 19.45425 ? 8   SER B OG  1 
ATOM   1209 N N   . GLN B 1 9   ? -25.34277 -18.68982 -2.46966  1.000 19.21241 ? 9   GLN B N   1 
ATOM   1210 C CA  . GLN B 1 9   ? -25.90259 -19.19661 -1.22742  1.000 21.77753 ? 9   GLN B CA  1 
ATOM   1211 C C   . GLN B 1 9   ? -26.31289 -18.03417 -0.32859  1.000 21.86354 ? 9   GLN B C   1 
ATOM   1212 O O   . GLN B 1 9   ? -25.59159 -17.04177 -0.21497  1.000 21.76080 ? 9   GLN B O   1 
ATOM   1213 C CB  . GLN B 1 9   ? -24.86996 -20.07589 -0.52644  1.000 21.88101 ? 9   GLN B CB  1 
ATOM   1214 C CG  . GLN B 1 9   ? -25.31392 -20.56021 0.83718   1.000 29.19450 ? 9   GLN B CG  1 
ATOM   1215 C CD  . GLN B 1 9   ? -26.07378 -21.86351 0.71427   1.000 37.47622 ? 9   GLN B CD  1 
ATOM   1216 O OE1 . GLN B 1 9   ? -27.15117 -22.04089 1.29497   1.000 41.46149 ? 9   GLN B OE1 1 
ATOM   1217 N NE2 . GLN B 1 9   ? -25.53139 -22.77453 -0.08048  1.000 37.21405 ? 9   GLN B NE2 1 
ATOM   1218 N N   . ASP B 1 10  ? -27.49248 -18.14989 0.27867   1.000 24.54227 ? 10  ASP B N   1 
ATOM   1219 C CA  . ASP B 1 10  ? -28.12794 -17.16692 1.16277   1.000 24.76864 ? 10  ASP B CA  1 
ATOM   1220 C C   . ASP B 1 10  ? -28.59968 -15.89702 0.45899   1.000 28.11087 ? 10  ASP B C   1 
ATOM   1221 O O   . ASP B 1 10  ? -29.08886 -14.99230 1.14362   1.000 25.20082 ? 10  ASP B O   1 
ATOM   1222 C CB  . ASP B 1 10  ? -27.23111 -16.73331 2.33578   1.000 33.39836 ? 10  ASP B CB  1 
ATOM   1223 C CG  . ASP B 1 10  ? -26.59884 -17.90901 3.06296   1.000 34.93541 ? 10  ASP B CG  1 
ATOM   1224 O OD1 . ASP B 1 10  ? -27.27804 -18.94247 3.23407   1.000 38.13154 ? 10  ASP B OD1 1 
ATOM   1225 O OD2 . ASP B 1 10  ? -25.41953 -17.79191 3.46116   1.000 41.60815 ? 10  ASP B OD2 1 
ATOM   1226 N N   . ARG B 1 11  ? -28.47598 -15.77965 -0.86848  1.000 18.77560 ? 11  ARG B N   1 
ATOM   1227 C CA  . ARG B 1 11  ? -29.03442 -14.59718 -1.51800  1.000 16.88716 ? 11  ARG B CA  1 
ATOM   1228 C C   . ARG B 1 11  ? -30.55884 -14.60192 -1.44098  1.000 18.44742 ? 11  ARG B C   1 
ATOM   1229 O O   . ARG B 1 11  ? -31.17506 -13.54797 -1.24899  1.000 19.89510 ? 11  ARG B O   1 
ATOM   1230 C CB  . ARG B 1 11  ? -28.56406 -14.49569 -2.97679  1.000 19.46344 ? 11  ARG B CB  1 
ATOM   1231 C CG  . ARG B 1 11  ? -29.23935 -13.34990 -3.76624  1.000 17.66119 ? 11  ARG B CG  1 
ATOM   1232 C CD  . ARG B 1 11  ? -28.97065 -12.03287 -3.05132  1.000 20.06070 ? 11  ARG B CD  1 
ATOM   1233 N NE  . ARG B 1 11  ? -29.44273 -10.85465 -3.77128  1.000 26.15965 ? 11  ARG B NE  1 
ATOM   1234 C CZ  . ARG B 1 11  ? -30.70130 -10.42883 -3.76183  1.000 33.33688 ? 11  ARG B CZ  1 
ATOM   1235 N NH1 . ARG B 1 11  ? -31.66716 -11.12721 -3.18413  1.000 25.69950 ? 11  ARG B NH1 1 
ATOM   1236 N NH2 . ARG B 1 11  ? -30.99616 -9.26042  -4.32469  1.000 25.76116 ? 11  ARG B NH2 1 
ATOM   1237 N N   . LEU B 1 12  ? -31.18840 -15.76752 -1.57694  1.000 14.82181 ? 12  LEU B N   1 
ATOM   1238 C CA  . LEU B 1 12  ? -32.64540 -15.85854 -1.58698  1.000 15.00781 ? 12  LEU B CA  1 
ATOM   1239 C C   . LEU B 1 12  ? -33.09731 -16.68958 -0.39855  1.000 16.94981 ? 12  LEU B C   1 
ATOM   1240 O O   . LEU B 1 12  ? -32.66248 -17.83599 -0.23764  1.000 16.24913 ? 12  LEU B O   1 
ATOM   1241 C CB  . LEU B 1 12  ? -33.17012 -16.48247 -2.88338  1.000 15.24545 ? 12  LEU B CB  1 
ATOM   1242 C CG  . LEU B 1 12  ? -32.68124 -15.86001 -4.19953  1.000 16.14865 ? 12  LEU B CG  1 
ATOM   1243 C CD1 . LEU B 1 12  ? -32.99019 -16.84326 -5.34090  1.000 13.62484 ? 12  LEU B CD1 1 
ATOM   1244 C CD2 . LEU B 1 12  ? -33.29123 -14.48828 -4.43672  1.000 19.41934 ? 12  LEU B CD2 1 
ATOM   1245 N N   . THR B 1 13  ? -33.96173 -16.10914 0.42990   1.000 20.54620 ? 13  THR B N   1 
ATOM   1246 C CA  . THR B 1 13  ? -34.61273 -16.84237 1.50544   1.000 17.77405 ? 13  THR B CA  1 
ATOM   1247 C C   . THR B 1 13  ? -35.54182 -17.88677 0.90425   1.000 21.67916 ? 13  THR B C   1 
ATOM   1248 O O   . THR B 1 13  ? -35.83086 -17.84636 -0.29444  1.000 15.22552 ? 13  THR B O   1 
ATOM   1249 C CB  . THR B 1 13  ? -35.39974 -15.87294 2.37741   1.000 18.00735 ? 13  THR B CB  1 
ATOM   1250 O OG1 . THR B 1 13  ? -36.41524 -15.26049 1.58362   1.000 20.95009 ? 13  THR B OG1 1 
ATOM   1251 C CG2 . THR B 1 13  ? -34.48935 -14.79547 2.92959   1.000 20.64170 ? 13  THR B CG2 1 
ATOM   1252 N N   . PRO B 1 14  ? -36.04219 -18.83940 1.71282   1.000 20.16716 ? 14  PRO B N   1 
ATOM   1253 C CA  . PRO B 1 14  ? -37.09583 -19.72246 1.19459   1.000 21.67940 ? 14  PRO B CA  1 
ATOM   1254 C C   . PRO B 1 14  ? -38.24740 -18.95830 0.57393   1.000 19.85626 ? 14  PRO B C   1 
ATOM   1255 O O   . PRO B 1 14  ? -38.72448 -19.35191 -0.48985  1.000 17.57710 ? 14  PRO B O   1 
ATOM   1256 C CB  . PRO B 1 14  ? -37.53562 -20.52195 2.43156   1.000 22.17828 ? 14  PRO B CB  1 
ATOM   1257 C CG  . PRO B 1 14  ? -36.34645 -20.53937 3.30960   1.000 23.19111 ? 14  PRO B CG  1 
ATOM   1258 C CD  . PRO B 1 14  ? -35.60729 -19.23615 3.06786   1.000 24.20478 ? 14  PRO B CD  1 
ATOM   1259 N N   . SER B 1 15  ? -38.69865 -17.85853 1.18835   1.000 20.15298 ? 15  SER B N   1 
ATOM   1260 C CA  . SER B 1 15  ? -39.83009 -17.14552 0.60790   1.000 19.37278 ? 15  SER B CA  1 
ATOM   1261 C C   . SER B 1 15  ? -39.44779 -16.49375 -0.71143  1.000 15.31832 ? 15  SER B C   1 
ATOM   1262 O O   . SER B 1 15  ? -40.25180 -16.46651 -1.65191  1.000 20.37784 ? 15  SER B O   1 
ATOM   1263 C CB  . SER B 1 15  ? -40.37040 -16.10575 1.58931   1.000 21.19601 ? 15  SER B CB  1 
ATOM   1264 O OG  . SER B 1 15  ? -40.27325 -16.58682 2.92163   1.000 32.19428 ? 15  SER B OG  1 
ATOM   1265 N N   . ALA B 1 16  ? -38.22390 -15.97201 -0.80026  1.000 18.86762 ? 16  ALA B N   1 
ATOM   1266 C CA  . ALA B 1 16  ? -37.77113 -15.35888 -2.04408  1.000 15.54948 ? 16  ALA B CA  1 
ATOM   1267 C C   . ALA B 1 16  ? -37.61265 -16.40308 -3.14999  1.000 14.96275 ? 16  ALA B C   1 
ATOM   1268 O O   . ALA B 1 16  ? -37.94286 -16.13420 -4.30907  1.000 16.64122 ? 16  ALA B O   1 
ATOM   1269 C CB  . ALA B 1 16  ? -36.45799 -14.61292 -1.80274  1.000 17.31714 ? 16  ALA B CB  1 
ATOM   1270 N N   . LYS B 1 17  ? -37.09463 -17.59310 -2.81620  1.000 19.75833 ? 17  LYS B N   1 
ATOM   1271 C CA  . LYS B 1 17  ? -36.99269 -18.66041 -3.81492  1.000 15.34929 ? 17  LYS B CA  1 
ATOM   1272 C C   . LYS B 1 17  ? -38.36313 -19.03450 -4.34801  1.000 17.39321 ? 17  LYS B C   1 
ATOM   1273 O O   . LYS B 1 17  ? -38.53726 -19.24722 -5.55587  1.000 15.65594 ? 17  LYS B O   1 
ATOM   1274 C CB  . LYS B 1 17  ? -36.31704 -19.89352 -3.21613  1.000 16.24032 ? 17  LYS B CB  1 
ATOM   1275 C CG  . LYS B 1 17  ? -34.83081 -19.74291 -2.97677  1.000 19.76403 ? 17  LYS B CG  1 
ATOM   1276 C CD  . LYS B 1 17  ? -34.23993 -21.04120 -2.47681  1.000 17.75836 ? 17  LYS B CD  1 
ATOM   1277 C CE  . LYS B 1 17  ? -32.81623 -20.81289 -2.01297  1.000 18.87804 ? 17  LYS B CE  1 
ATOM   1278 N NZ  . LYS B 1 17  ? -32.36229 -21.95301 -1.20553  1.000 27.73795 ? 17  LYS B NZ  1 
ATOM   1279 N N   . HIS B 1 18  ? -39.34645 -19.14887 -3.45272  1.000 18.21210 ? 18  HIS B N   1 
ATOM   1280 C CA  . HIS B 1 18  ? -40.70506 -19.43400 -3.89293  1.000 17.72513 ? 18  HIS B CA  1 
ATOM   1281 C C   . HIS B 1 18  ? -41.21096 -18.36839 -4.85898  1.000 18.36072 ? 18  HIS B C   1 
ATOM   1282 O O   . HIS B 1 18  ? -41.81837 -18.68669 -5.88941  1.000 17.83233 ? 18  HIS B O   1 
ATOM   1283 C CB  . HIS B 1 18  ? -41.63750 -19.55983 -2.68438  1.000 20.52414 ? 18  HIS B CB  1 
ATOM   1284 C CG  . HIS B 1 18  ? -43.00563 -20.04977 -3.04463  1.000 23.36387 ? 18  HIS B CG  1 
ATOM   1285 N ND1 . HIS B 1 18  ? -43.45829 -21.30826 -2.71708  1.000 26.58130 ? 18  HIS B ND1 1 
ATOM   1286 C CD2 . HIS B 1 18  ? -44.00812 -19.45831 -3.73789  1.000 31.30734 ? 18  HIS B CD2 1 
ATOM   1287 C CE1 . HIS B 1 18  ? -44.68386 -21.46814 -3.18383  1.000 27.18811 ? 18  HIS B CE1 1 
ATOM   1288 N NE2 . HIS B 1 18  ? -45.04163 -20.36068 -3.80731  1.000 30.15619 ? 18  HIS B NE2 1 
ATOM   1289 N N   . ALA B 1 19  ? -40.97532 -17.09568 -4.53977  1.000 17.54237 ? 19  ALA B N   1 
ATOM   1290 C CA  . ALA B 1 19  ? -41.47029 -16.01854 -5.38575  1.000 16.00639 ? 19  ALA B CA  1 
ATOM   1291 C C   . ALA B 1 19  ? -40.77405 -16.02216 -6.73919  1.000 16.93648 ? 19  ALA B C   1 
ATOM   1292 O O   . ALA B 1 19  ? -41.41428 -15.80924 -7.77740  1.000 18.59322 ? 19  ALA B O   1 
ATOM   1293 C CB  . ALA B 1 19  ? -41.26894 -14.67630 -4.68992  1.000 19.84371 ? 19  ALA B CB  1 
ATOM   1294 N N   . VAL B 1 20  ? -39.46246 -16.26840 -6.74292  1.000 13.78028 ? 20  VAL B N   1 
ATOM   1295 C CA  . VAL B 1 20  ? -38.72898 -16.34559 -8.00709  1.000 13.44062 ? 20  VAL B CA  1 
ATOM   1296 C C   . VAL B 1 20  ? -39.23084 -17.51615 -8.84550  1.000 17.09992 ? 20  VAL B C   1 
ATOM   1297 O O   . VAL B 1 20  ? -39.44986 -17.38736 -10.05768 1.000 14.57182 ? 20  VAL B O   1 
ATOM   1298 C CB  . VAL B 1 20  ? -37.22554 -16.45919 -7.73418  1.000 14.33640 ? 20  VAL B CB  1 
ATOM   1299 C CG1 . VAL B 1 20  ? -36.50339 -16.79433 -9.03299  1.000 13.49884 ? 20  VAL B CG1 1 
ATOM   1300 C CG2 . VAL B 1 20  ? -36.69318 -15.15368 -7.15028  1.000 17.92063 ? 20  VAL B CG2 1 
ATOM   1301 N N   . ALA B 1 21  ? -39.42281 -18.67874 -8.21864  1.000 14.23169 ? 21  ALA B N   1 
ATOM   1302 C CA  . ALA B 1 21  ? -39.96196 -19.80991 -8.97173  1.000 14.50458 ? 21  ALA B CA  1 
ATOM   1303 C C   . ALA B 1 21  ? -41.36816 -19.51745 -9.48416  1.000 19.18392 ? 21  ALA B C   1 
ATOM   1304 O O   . ALA B 1 21  ? -41.72734 -19.91044 -10.60323 1.000 15.44681 ? 21  ALA B O   1 
ATOM   1305 C CB  . ALA B 1 21  ? -39.95695 -21.07105 -8.11414  1.000 16.06244 ? 21  ALA B CB  1 
ATOM   1306 N N   . LYS B 1 22  ? -42.19381 -18.85950 -8.66605  1.000 19.28627 ? 22  LYS B N   1 
ATOM   1307 C CA  . LYS B 1 22  ? -43.52060 -18.48359 -9.12320  1.000 18.86104 ? 22  LYS B CA  1 
ATOM   1308 C C   . LYS B 1 22  ? -43.43331 -17.54899 -10.31448 1.000 16.26674 ? 22  LYS B C   1 
ATOM   1309 O O   . LYS B 1 22  ? -44.17680 -17.70673 -11.28871 1.000 17.58267 ? 22  LYS B O   1 
ATOM   1310 C CB  . LYS B 1 22  ? -44.30973 -17.81148 -7.99883  1.000 18.17020 ? 22  LYS B CB  1 
ATOM   1311 C CG  . LYS B 1 22  ? -45.72611 -17.46799 -8.39867  1.000 28.01488 ? 22  LYS B CG  1 
ATOM   1312 C CD  . LYS B 1 22  ? -46.51176 -16.92930 -7.21168  1.000 25.32738 ? 22  LYS B CD  1 
ATOM   1313 C CE  . LYS B 1 22  ? -47.50559 -15.85559 -7.63896  1.000 30.86548 ? 22  LYS B CE  1 
ATOM   1314 N NZ  . LYS B 1 22  ? -48.40165 -16.31437 -8.74768  1.000 34.21693 ? 22  LYS B NZ  1 
ATOM   1315 N N   . ALA B 1 23  ? -42.53126 -16.56454 -10.25131 1.000 15.50241 ? 23  ALA B N   1 
ATOM   1316 C CA  . ALA B 1 23  ? -42.40048 -15.60684 -11.34398 1.000 17.29919 ? 23  ALA B CA  1 
ATOM   1317 C C   . ALA B 1 23  ? -42.05216 -16.31212 -12.64844 1.000 17.12980 ? 23  ALA B C   1 
ATOM   1318 O O   . ALA B 1 23  ? -42.64444 -16.03718 -13.69765 1.000 15.83736 ? 23  ALA B O   1 
ATOM   1319 C CB  . ALA B 1 23  ? -41.33229 -14.56902 -11.00426 1.000 18.76433 ? 23  ALA B CB  1 
ATOM   1320 N N   . ILE B 1 24  ? -41.07648 -17.21577 -12.59642 1.000 14.73824 ? 24  ILE B N   1 
ATOM   1321 C CA  . ILE B 1 24  ? -40.63800 -17.91479 -13.80031 1.000 14.27572 ? 24  ILE B CA  1 
ATOM   1322 C C   . ILE B 1 24  ? -41.73539 -18.84412 -14.30223 1.000 16.25996 ? 24  ILE B C   1 
ATOM   1323 O O   . ILE B 1 24  ? -42.05816 -18.86398 -15.49458 1.000 14.33913 ? 24  ILE B O   1 
ATOM   1324 C CB  . ILE B 1 24  ? -39.33863 -18.68415 -13.51687 1.000 15.62903 ? 24  ILE B CB  1 
ATOM   1325 C CG1 . ILE B 1 24  ? -38.18324 -17.71288 -13.26251 1.000 17.48540 ? 24  ILE B CG1 1 
ATOM   1326 C CG2 . ILE B 1 24  ? -39.03779 -19.62164 -14.67134 1.000 16.06763 ? 24  ILE B CG2 1 
ATOM   1327 C CD1 . ILE B 1 24  ? -36.89577 -18.38199 -12.80423 1.000 14.09908 ? 24  ILE B CD1 1 
ATOM   1328 N N   . THR B 1 25  ? -42.33613 -19.61451 -13.39109 1.000 14.74248 ? 25  THR B N   1 
ATOM   1329 C CA  . THR B 1 25  ? -43.36637 -20.56977 -13.78727 1.000 15.13773 ? 25  THR B CA  1 
ATOM   1330 C C   . THR B 1 25  ? -44.57832 -19.85572 -14.37205 1.000 19.16602 ? 25  THR B C   1 
ATOM   1331 O O   . THR B 1 25  ? -45.13279 -20.28849 -15.38842 1.000 15.18054 ? 25  THR B O   1 
ATOM   1332 C CB  . THR B 1 25  ? -43.76728 -21.41947 -12.57856 1.000 16.08172 ? 25  THR B CB  1 
ATOM   1333 O OG1 . THR B 1 25  ? -42.60654 -22.06549 -12.05199 1.000 17.58880 ? 25  THR B OG1 1 
ATOM   1334 C CG2 . THR B 1 25  ? -44.80139 -22.46660 -12.96537 1.000 19.52370 ? 25  THR B CG2 1 
ATOM   1335 N N   . ASP B 1 26  ? -45.01144 -18.76017 -13.73195 1.000 18.40983 ? 26  ASP B N   1 
ATOM   1336 C CA  . ASP B 1 26  ? -46.13296 -17.98670 -14.26271 1.000 18.82536 ? 26  ASP B CA  1 
ATOM   1337 C C   . ASP B 1 26  ? -45.81631 -17.43880 -15.64237 1.000 20.22021 ? 26  ASP B C   1 
ATOM   1338 O O   . ASP B 1 26  ? -46.67093 -17.46506 -16.53204 1.000 18.98412 ? 26  ASP B O   1 
ATOM   1339 C CB  . ASP B 1 26  ? -46.49444 -16.83288 -13.31756 1.000 20.38081 ? 26  ASP B CB  1 
ATOM   1340 C CG  . ASP B 1 26  ? -47.22806 -17.29773 -12.07526 1.000 25.14334 ? 26  ASP B CG  1 
ATOM   1341 O OD1 . ASP B 1 26  ? -47.56888 -18.49100 -11.99597 1.000 24.86979 ? 26  ASP B OD1 1 
ATOM   1342 O OD2 . ASP B 1 26  ? -47.43776 -16.46676 -11.16115 1.000 26.61244 ? 26  ASP B OD2 1 
ATOM   1343 N N   . ALA B 1 27  ? -44.60059 -16.90921 -15.83311 1.000 19.17008 ? 27  ALA B N   1 
ATOM   1344 C CA  . ALA B 1 27  ? -44.21768 -16.39654 -17.14643 1.000 15.81811 ? 27  ALA B CA  1 
ATOM   1345 C C   . ALA B 1 27  ? -44.30798 -17.48320 -18.20574 1.000 14.93707 ? 27  ALA B C   1 
ATOM   1346 O O   . ALA B 1 27  ? -44.82725 -17.25221 -19.30113 1.000 16.97010 ? 27  ALA B O   1 
ATOM   1347 C CB  . ALA B 1 27  ? -42.79793 -15.82757 -17.10690 1.000 17.74212 ? 27  ALA B CB  1 
ATOM   1348 N N   . HIS B 1 28  ? -43.82098 -18.67714 -17.88849 1.000 17.61042 ? 28  HIS B N   1 
ATOM   1349 C CA  . HIS B 1 28  ? -43.83725 -19.75622 -18.86784 1.000 17.10282 ? 28  HIS B CA  1 
ATOM   1350 C C   . HIS B 1 28  ? -45.26548 -20.18717 -19.18221 1.000 16.99852 ? 28  HIS B C   1 
ATOM   1351 O O   . HIS B 1 28  ? -45.63002 -20.36236 -20.35197 1.000 19.32404 ? 28  HIS B O   1 
ATOM   1352 C CB  . HIS B 1 28  ? -43.02300 -20.94067 -18.35268 1.000 15.78174 ? 28  HIS B CB  1 
ATOM   1353 C CG  . HIS B 1 28  ? -42.69166 -21.93389 -19.41508 1.000 19.41205 ? 28  HIS B CG  1 
ATOM   1354 N ND1 . HIS B 1 28  ? -41.56421 -21.82343 -20.20484 1.000 15.99623 ? 28  HIS B ND1 1 
ATOM   1355 C CD2 . HIS B 1 28  ? -43.35559 -23.03153 -19.85107 1.000 20.44293 ? 28  HIS B CD2 1 
ATOM   1356 C CE1 . HIS B 1 28  ? -41.54616 -22.81790 -21.07535 1.000 18.14027 ? 28  HIS B CE1 1 
ATOM   1357 N NE2 . HIS B 1 28  ? -42.61944 -23.56382 -20.88228 1.000 19.36174 ? 28  HIS B NE2 1 
ATOM   1358 N N   . ARG B 1 29  ? -46.08768 -20.37749 -18.14759 1.000 17.35980 ? 29  ARG B N   1 
ATOM   1359 C CA  . ARG B 1 29  ? -47.47983 -20.75540 -18.38544 1.000 17.68928 ? 29  ARG B CA  1 
ATOM   1360 C C   . ARG B 1 29  ? -48.19374 -19.67621 -19.18692 1.000 18.26908 ? 29  ARG B C   1 
ATOM   1361 O O   . ARG B 1 29  ? -48.92201 -19.96603 -20.14555 1.000 17.90324 ? 29  ARG B O   1 
ATOM   1362 C CB  . ARG B 1 29  ? -48.20442 -20.97715 -17.05739 1.000 21.87645 ? 29  ARG B CB  1 
ATOM   1363 C CG  . ARG B 1 29  ? -49.44445 -21.86845 -17.18909 1.000 31.22639 ? 29  ARG B CG  1 
ATOM   1364 C CD  . ARG B 1 29  ? -50.74436 -21.13436 -17.20062 1.000 38.05746 ? 29  ARG B CD  1 
ATOM   1365 N NE  . ARG B 1 29  ? -51.78319 -22.01074 -17.73216 1.000 32.63871 ? 29  ARG B NE  1 
ATOM   1366 C CZ  . ARG B 1 29  ? -52.48166 -21.75798 -18.83242 1.000 39.51382 ? 29  ARG B CZ  1 
ATOM   1367 N NH1 . ARG B 1 29  ? -52.28300 -20.65848 -19.54347 1.000 32.98008 ? 29  ARG B NH1 1 
ATOM   1368 N NH2 . ARG B 1 29  ? -53.39737 -22.63369 -19.23528 1.000 53.41962 ? 29  ARG B NH2 1 
ATOM   1369 N N   . GLY B 1 30  ? -48.01122 -18.41266 -18.78541 1.000 20.57552 ? 30  GLY B N   1 
ATOM   1370 C CA  . GLY B 1 30  ? -48.73862 -17.32210 -19.41949 1.000 20.94865 ? 30  GLY B CA  1 
ATOM   1371 C C   . GLY B 1 30  ? -48.41765 -17.13477 -20.89044 1.000 23.32886 ? 30  GLY B C   1 
ATOM   1372 O O   . GLY B 1 30  ? -49.29896 -16.80098 -21.68466 1.000 20.35678 ? 30  GLY B O   1 
ATOM   1373 N N   . LEU B 1 31  ? -47.15111 -17.32445 -21.28135 1.000 18.16163 ? 31  LEU B N   1 
ATOM   1374 C CA  . LEU B 1 31  ? -46.79679 -17.07737 -22.67130 1.000 18.46390 ? 31  LEU B CA  1 
ATOM   1375 C C   . LEU B 1 31  ? -46.83872 -18.31681 -23.55205 1.000 18.55376 ? 31  LEU B C   1 
ATOM   1376 O O   . LEU B 1 31  ? -46.99007 -18.17737 -24.76658 1.000 18.92701 ? 31  LEU B O   1 
ATOM   1377 C CB  . LEU B 1 31  ? -45.41022 -16.43337 -22.78909 1.000 16.34771 ? 31  LEU B CB  1 
ATOM   1378 C CG  . LEU B 1 31  ? -45.36798 -14.99290 -22.25474 1.000 18.07796 ? 31  LEU B CG  1 
ATOM   1379 C CD1 . LEU B 1 31  ? -43.97283 -14.66444 -21.74145 1.000 21.42435 ? 31  LEU B CD1 1 
ATOM   1380 C CD2 . LEU B 1 31  ? -45.81933 -13.99854 -23.32241 1.000 30.80863 ? 31  LEU B CD2 1 
ATOM   1381 N N   . THR B 1 32  ? -46.71510 -19.51396 -22.98929 1.000 19.67125 ? 32  THR B N   1 
ATOM   1382 C CA  . THR B 1 32  ? -46.68905 -20.72650 -23.79746 1.000 17.56641 ? 32  THR B CA  1 
ATOM   1383 C C   . THR B 1 32  ? -47.95105 -21.56828 -23.68333 1.000 24.34214 ? 32  THR B C   1 
ATOM   1384 O O   . THR B 1 32  ? -48.20113 -22.40183 -24.56208 1.000 22.60521 ? 32  THR B O   1 
ATOM   1385 C CB  . THR B 1 32  ? -45.48358 -21.60764 -23.42175 1.000 21.55021 ? 32  THR B CB  1 
ATOM   1386 O OG1 . THR B 1 32  ? -45.70903 -22.23437 -22.14959 1.000 20.04352 ? 32  THR B OG1 1 
ATOM   1387 C CG2 . THR B 1 32  ? -44.18622 -20.78602 -23.36496 1.000 18.77831 ? 32  THR B CG2 1 
ATOM   1388 N N   . GLY B 1 33  ? -48.74977 -21.37719 -22.64100 1.000 23.15516 ? 33  GLY B N   1 
ATOM   1389 C CA  . GLY B 1 33  ? -49.88606 -22.24317 -22.42712 1.000 23.97049 ? 33  GLY B CA  1 
ATOM   1390 C C   . GLY B 1 33  ? -49.56535 -23.57358 -21.78550 1.000 26.17365 ? 33  GLY B C   1 
ATOM   1391 O O   . GLY B 1 33  ? -50.49375 -24.33614 -21.48997 1.000 28.57018 ? 33  GLY B O   1 
ATOM   1392 N N   . THR B 1 34  ? -48.28984 -23.87573 -21.55747 1.000 21.72692 ? 34  THR B N   1 
ATOM   1393 C CA  . THR B 1 34  ? -47.89193 -25.12894 -20.92984 1.000 24.06344 ? 34  THR B CA  1 
ATOM   1394 C C   . THR B 1 34  ? -48.35721 -25.15997 -19.48011 1.000 24.51020 ? 34  THR B C   1 
ATOM   1395 O O   . THR B 1 34  ? -48.19891 -24.17746 -18.75391 1.000 27.97567 ? 34  THR B O   1 
ATOM   1396 C CB  . THR B 1 34  ? -46.36929 -25.28609 -21.00088 1.000 24.08878 ? 34  THR B CB  1 
ATOM   1397 O OG1 . THR B 1 34  ? -45.96379 -25.46281 -22.36336 1.000 28.48023 ? 34  THR B OG1 1 
ATOM   1398 C CG2 . THR B 1 34  ? -45.89270 -26.46953 -20.15560 1.000 24.29013 ? 34  THR B CG2 1 
ATOM   1399 N N   . GLN B 1 35  ? -48.93012 -26.29002 -19.05324 1.000 25.74576 ? 35  GLN B N   1 
ATOM   1400 C CA  . GLN B 1 35  ? -49.47032 -26.38074 -17.70176 1.000 26.89035 ? 35  GLN B CA  1 
ATOM   1401 C C   . GLN B 1 35  ? -48.39782 -26.04005 -16.67927 1.000 22.23707 ? 35  GLN B C   1 
ATOM   1402 O O   . GLN B 1 35  ? -47.20596 -26.29933 -16.88887 1.000 23.40240 ? 35  GLN B O   1 
ATOM   1403 C CB  . GLN B 1 35  ? -50.00240 -27.78094 -17.40739 1.000 25.81224 ? 35  GLN B CB  1 
ATOM   1404 C CG  . GLN B 1 35  ? -51.22055 -28.17375 -18.19415 1.000 26.63618 ? 35  GLN B CG  1 
ATOM   1405 C CD  . GLN B 1 35  ? -50.82240 -29.03429 -19.36470 1.000 31.42441 ? 35  GLN B CD  1 
ATOM   1406 O OE1 . GLN B 1 35  ? -49.72542 -28.87584 -19.89860 1.000 29.16132 ? 35  GLN B OE1 1 
ATOM   1407 N NE2 . GLN B 1 35  ? -51.68188 -29.97124 -19.74941 1.000 27.62325 ? 35  GLN B NE2 1 
ATOM   1408 N N   . HIS B 1 36  ? -48.83814 -25.44633 -15.56707 1.000 23.96994 ? 36  HIS B N   1 
ATOM   1409 C CA  . HIS B 1 36  ? -47.92528 -25.05558 -14.50028 1.000 20.51749 ? 36  HIS B CA  1 
ATOM   1410 C C   . HIS B 1 36  ? -47.04614 -26.21903 -14.08775 1.000 19.90524 ? 36  HIS B C   1 
ATOM   1411 O O   . HIS B 1 36  ? -45.82771 -26.07535 -13.96618 1.000 16.57521 ? 36  HIS B O   1 
ATOM   1412 C CB  . HIS B 1 36  ? -48.72314 -24.55695 -13.29538 1.000 26.25066 ? 36  HIS B CB  1 
ATOM   1413 C CG  . HIS B 1 36  ? -49.00364 -23.09085 -13.32088 1.000 24.81593 ? 36  HIS B CG  1 
ATOM   1414 N ND1 . HIS B 1 36  ? -50.17556 -22.57188 -13.83083 1.000 36.70638 ? 36  HIS B ND1 1 
ATOM   1415 C CD2 . HIS B 1 36  ? -48.29258 -22.03591 -12.85976 1.000 30.29819 ? 36  HIS B CD2 1 
ATOM   1416 C CE1 . HIS B 1 36  ? -50.15793 -21.25660 -13.71296 1.000 39.53295 ? 36  HIS B CE1 1 
ATOM   1417 N NE2 . HIS B 1 36  ? -49.02764 -20.90613 -13.12497 1.000 33.73967 ? 36  HIS B NE2 1 
ATOM   1418 N N   . PHE B 1 37  ? -47.65171 -27.39483 -13.87745 1.000 17.58094 ? 37  PHE B N   1 
ATOM   1419 C CA  . PHE B 1 37  ? -46.90378 -28.51173 -13.31413 1.000 17.85476 ? 37  PHE B CA  1 
ATOM   1420 C C   . PHE B 1 37  ? -45.81784 -29.04990 -14.24977 1.000 18.24300 ? 37  PHE B C   1 
ATOM   1421 O O   . PHE B 1 37  ? -44.97739 -29.83267 -13.79737 1.000 20.07486 ? 37  PHE B O   1 
ATOM   1422 C CB  . PHE B 1 37  ? -47.84908 -29.65185 -12.90125 1.000 20.31248 ? 37  PHE B CB  1 
ATOM   1423 C CG  . PHE B 1 37  ? -48.80116 -30.08367 -13.98235 1.000 20.76272 ? 37  PHE B CG  1 
ATOM   1424 C CD1 . PHE B 1 37  ? -48.37941 -30.90379 -15.01789 1.000 22.48647 ? 37  PHE B CD1 1 
ATOM   1425 C CD2 . PHE B 1 37  ? -50.12963 -29.70652 -13.93821 1.000 22.37672 ? 37  PHE B CD2 1 
ATOM   1426 C CE1 . PHE B 1 37  ? -49.26105 -31.31068 -16.01087 1.000 23.95593 ? 37  PHE B CE1 1 
ATOM   1427 C CE2 . PHE B 1 37  ? -51.02192 -30.11081 -14.93333 1.000 21.11943 ? 37  PHE B CE2 1 
ATOM   1428 C CZ  . PHE B 1 37  ? -50.58243 -30.90873 -15.96459 1.000 21.47856 ? 37  PHE B CZ  1 
ATOM   1429 N N   . LEU B 1 38  ? -45.79245 -28.64614 -15.51349 1.000 16.04495 ? 38  LEU B N   1 
ATOM   1430 C CA  . LEU B 1 38  ? -44.73006 -29.09658 -16.40482 1.000 17.13562 ? 38  LEU B CA  1 
ATOM   1431 C C   . LEU B 1 38  ? -43.48505 -28.21771 -16.33633 1.000 17.75831 ? 38  LEU B C   1 
ATOM   1432 O O   . LEU B 1 38  ? -42.49044 -28.53444 -16.99565 1.000 16.76677 ? 38  LEU B O   1 
ATOM   1433 C CB  . LEU B 1 38  ? -45.23284 -29.15875 -17.84621 1.000 18.64691 ? 38  LEU B CB  1 
ATOM   1434 C CG  . LEU B 1 38  ? -46.25119 -30.26692 -18.14280 1.000 21.31660 ? 38  LEU B CG  1 
ATOM   1435 C CD1 . LEU B 1 38  ? -46.69500 -30.17292 -19.57823 1.000 22.33504 ? 38  LEU B CD1 1 
ATOM   1436 C CD2 . LEU B 1 38  ? -45.69950 -31.66169 -17.81018 1.000 17.52482 ? 38  LEU B CD2 1 
ATOM   1437 N N   . ALA B 1 39  ? -43.50438 -27.13480 -15.55707 1.000 17.36885 ? 39  ALA B N   1 
ATOM   1438 C CA  . ALA B 1 39  ? -42.35980 -26.23357 -15.44163 1.000 13.77777 ? 39  ALA B CA  1 
ATOM   1439 C C   . ALA B 1 39  ? -41.62011 -26.50303 -14.13893 1.000 17.78495 ? 39  ALA B C   1 
ATOM   1440 O O   . ALA B 1 39  ? -42.19294 -26.34505 -13.04614 1.000 16.09895 ? 39  ALA B O   1 
ATOM   1441 C CB  . ALA B 1 39  ? -42.80694 -24.76920 -15.50794 1.000 15.54378 ? 39  ALA B CB  1 
ATOM   1442 N N   . GLN B 1 40  ? -40.34498 -26.90387 -14.25647 1.000 15.11111 ? 40  GLN B N   1 
ATOM   1443 C CA  . GLN B 1 40  ? -39.46433 -27.08884 -13.11403 1.000 12.92874 ? 40  GLN B CA  1 
ATOM   1444 C C   . GLN B 1 40  ? -38.54069 -25.87948 -12.98169 1.000 12.32094 ? 40  GLN B C   1 
ATOM   1445 O O   . GLN B 1 40  ? -38.00780 -25.37801 -13.97983 1.000 12.18677 ? 40  GLN B O   1 
ATOM   1446 C CB  . GLN B 1 40  ? -38.63551 -28.37798 -13.24474 1.000 11.46179 ? 40  GLN B CB  1 
ATOM   1447 C CG  . GLN B 1 40  ? -37.52989 -28.47870 -12.18364 1.000 15.13075 ? 40  GLN B CG  1 
ATOM   1448 C CD  . GLN B 1 40  ? -36.79102 -29.80949 -12.14999 1.000 13.80608 ? 40  GLN B CD  1 
ATOM   1449 O OE1 . GLN B 1 40  ? -35.70859 -29.90174 -11.56978 1.000 18.47885 ? 40  GLN B OE1 1 
ATOM   1450 N NE2 . GLN B 1 40  ? -37.39606 -30.85768 -12.71438 1.000 14.02337 ? 40  GLN B NE2 1 
ATOM   1451 N N   . VAL B 1 41  ? -38.37872 -25.39810 -11.74983 1.000 13.67822 ? 41  VAL B N   1 
ATOM   1452 C CA  . VAL B 1 41  ? -37.35714 -24.40434 -11.41899 1.000 15.35815 ? 41  VAL B CA  1 
ATOM   1453 C C   . VAL B 1 41  ? -36.40574 -25.03707 -10.41755 1.000 13.05482 ? 41  VAL B C   1 
ATOM   1454 O O   . VAL B 1 41  ? -36.82498 -25.52521 -9.36238  1.000 13.49042 ? 41  VAL B O   1 
ATOM   1455 C CB  . VAL B 1 41  ? -37.96078 -23.09868 -10.87751 1.000 12.32718 ? 41  VAL B CB  1 
ATOM   1456 C CG1 . VAL B 1 41  ? -36.82064 -22.14490 -10.42555 1.000 11.06835 ? 41  VAL B CG1 1 
ATOM   1457 C CG2 . VAL B 1 41  ? -38.82143 -22.42940 -11.95701 1.000 12.99006 ? 41  VAL B CG2 1 
ATOM   1458 N N   . ASN B 1 42  ? -35.12801 -25.04829 -10.75302 1.000 11.24580 ? 42  ASN B N   1 
ATOM   1459 C CA  . ASN B 1 42  ? -34.13215 -25.82755 -10.03315 1.000 11.57891 ? 42  ASN B CA  1 
ATOM   1460 C C   . ASN B 1 42  ? -33.02091 -24.87783 -9.60601  1.000 11.99984 ? 42  ASN B C   1 
ATOM   1461 O O   . ASN B 1 42  ? -32.16795 -24.51373 -10.42324 1.000 13.33804 ? 42  ASN B O   1 
ATOM   1462 C CB  . ASN B 1 42  ? -33.61153 -26.95611 -10.91832 1.000 13.28210 ? 42  ASN B CB  1 
ATOM   1463 C CG  . ASN B 1 42  ? -32.85999 -28.00657 -10.14096 1.000 17.74396 ? 42  ASN B CG  1 
ATOM   1464 O OD1 . ASN B 1 42  ? -32.03622 -27.67964 -9.29837  1.000 17.18302 ? 42  ASN B OD1 1 
ATOM   1465 N ND2 . ASN B 1 42  ? -33.08812 -29.27645 -10.46666 1.000 16.08557 ? 42  ASN B ND2 1 
ATOM   1466 N N   . PHE B 1 43  ? -33.03807 -24.48224 -8.33002  1.000 16.47905 ? 43  PHE B N   1 
ATOM   1467 C CA  . PHE B 1 43  ? -32.05689 -23.54154 -7.80236  1.000 13.75156 ? 43  PHE B CA  1 
ATOM   1468 C C   . PHE B 1 43  ? -30.74125 -24.24539 -7.51587  1.000 13.98418 ? 43  PHE B C   1 
ATOM   1469 O O   . PHE B 1 43  ? -30.70140 -25.26326 -6.81016  1.000 12.22592 ? 43  PHE B O   1 
ATOM   1470 C CB  . PHE B 1 43  ? -32.58276 -22.88014 -6.52503  1.000 11.82184 ? 43  PHE B CB  1 
ATOM   1471 C CG  . PHE B 1 43  ? -33.65691 -21.86516 -6.77680  1.000 10.88499 ? 43  PHE B CG  1 
ATOM   1472 C CD1 . PHE B 1 43  ? -33.35044 -20.56937 -7.18054  1.000 12.89329 ? 43  PHE B CD1 1 
ATOM   1473 C CD2 . PHE B 1 43  ? -34.99273 -22.23748 -6.66422  1.000 13.18718 ? 43  PHE B CD2 1 
ATOM   1474 C CE1 . PHE B 1 43  ? -34.37373 -19.65107 -7.43006  1.000 14.86192 ? 43  PHE B CE1 1 
ATOM   1475 C CE2 . PHE B 1 43  ? -36.01525 -21.33652 -6.91556  1.000 15.73952 ? 43  PHE B CE2 1 
ATOM   1476 C CZ  . PHE B 1 43  ? -35.71015 -20.04516 -7.29958  1.000 15.61361 ? 43  PHE B CZ  1 
ATOM   1477 N N   . GLN B 1 44  ? -29.66162 -23.68398 -8.05895  1.000 12.96625 ? 44  GLN B N   1 
ATOM   1478 C CA  . GLN B 1 44  ? -28.30084 -24.18032 -7.88066  1.000 12.28156 ? 44  GLN B CA  1 
ATOM   1479 C C   . GLN B 1 44  ? -27.52320 -23.09118 -7.14395  1.000 12.61113 ? 44  GLN B C   1 
ATOM   1480 O O   . GLN B 1 44  ? -27.14416 -22.07757 -7.74669  1.000 13.93414 ? 44  GLN B O   1 
ATOM   1481 C CB  . GLN B 1 44  ? -27.65702 -24.52133 -9.23987  1.000 11.26606 ? 44  GLN B CB  1 
ATOM   1482 C CG  . GLN B 1 44  ? -28.40863 -25.63843 -10.01842 1.000 11.34403 ? 44  GLN B CG  1 
ATOM   1483 C CD  . GLN B 1 44  ? -28.16226 -27.01117 -9.42974  1.000 18.93582 ? 44  GLN B CD  1 
ATOM   1484 O OE1 . GLN B 1 44  ? -27.01485 -27.42301 -9.23630  1.000 21.34952 ? 44  GLN B OE1 1 
ATOM   1485 N NE2 . GLN B 1 44  ? -29.24124 -27.73069 -9.13722  1.000 13.79679 ? 44  GLN B NE2 1 
ATOM   1486 N N   . GLU B 1 45  ? -27.29328 -23.30013 -5.84597  1.000 13.75982 ? 45  GLU B N   1 
ATOM   1487 C CA  . GLU B 1 45  ? -26.60137 -22.33823 -4.99460  1.000 12.88380 ? 45  GLU B CA  1 
ATOM   1488 C C   . GLU B 1 45  ? -25.13525 -22.69724 -4.86343  1.000 13.24030 ? 45  GLU B C   1 
ATOM   1489 O O   . GLU B 1 45  ? -24.78486 -23.87668 -4.71696  1.000 13.48388 ? 45  GLU B O   1 
ATOM   1490 C CB  . GLU B 1 45  ? -27.21913 -22.29440 -3.59828  1.000 18.05069 ? 45  GLU B CB  1 
ATOM   1491 C CG  . GLU B 1 45  ? -28.61485 -21.70516 -3.56213  1.000 15.62743 ? 45  GLU B CG  1 
ATOM   1492 C CD  . GLU B 1 45  ? -29.26105 -21.83741 -2.19212  1.000 22.44530 ? 45  GLU B CD  1 
ATOM   1493 O OE1 . GLU B 1 45  ? -29.43455 -22.98794 -1.74468  1.000 21.29733 ? 45  GLU B OE1 1 
ATOM   1494 O OE2 . GLU B 1 45  ? -29.61064 -20.79759 -1.58346  1.000 22.30664 ? 45  GLU B OE2 1 
ATOM   1495 N N   . GLN B 1 46  ? -24.28914 -21.67422 -4.90947  1.000 13.85790 ? 46  GLN B N   1 
ATOM   1496 C CA  . GLN B 1 46  ? -22.85793 -21.77019 -4.66817  1.000 13.26997 ? 46  GLN B CA  1 
ATOM   1497 C C   . GLN B 1 46  ? -22.46387 -20.61379 -3.76636  1.000 13.97915 ? 46  GLN B C   1 
ATOM   1498 O O   . GLN B 1 46  ? -23.15300 -19.59010 -3.72859  1.000 18.17302 ? 46  GLN B O   1 
ATOM   1499 C CB  . GLN B 1 46  ? -22.04426 -21.71761 -5.97186  1.000 15.97557 ? 46  GLN B CB  1 
ATOM   1500 C CG  . GLN B 1 46  ? -22.24495 -22.94217 -6.86494  1.000 13.41518 ? 46  GLN B CG  1 
ATOM   1501 C CD  . GLN B 1 46  ? -21.50926 -24.14588 -6.35187  1.000 15.87281 ? 46  GLN B CD  1 
ATOM   1502 O OE1 . GLN B 1 46  ? -20.35488 -24.05015 -5.94322  1.000 18.46039 ? 46  GLN B OE1 1 
ATOM   1503 N NE2 . GLN B 1 46  ? -22.17857 -25.29934 -6.36197  1.000 16.66256 ? 46  GLN B NE2 1 
ATOM   1504 N N   . PRO B 1 47  ? -21.36812 -20.74570 -3.01979  1.000 19.56889 ? 47  PRO B N   1 
ATOM   1505 C CA  . PRO B 1 47  ? -20.92330 -19.61811 -2.19221  1.000 20.55986 ? 47  PRO B CA  1 
ATOM   1506 C C   . PRO B 1 47  ? -20.65706 -18.38797 -3.04193  1.000 20.23936 ? 47  PRO B C   1 
ATOM   1507 O O   . PRO B 1 47  ? -20.23763 -18.48152 -4.19567  1.000 18.06077 ? 47  PRO B O   1 
ATOM   1508 C CB  . PRO B 1 47  ? -19.63980 -20.14284 -1.53336  1.000 22.75086 ? 47  PRO B CB  1 
ATOM   1509 C CG  . PRO B 1 47  ? -19.19971 -21.28731 -2.37959  1.000 20.64774 ? 47  PRO B CG  1 
ATOM   1510 C CD  . PRO B 1 47  ? -20.48040 -21.91176 -2.87502  1.000 15.24377 ? 47  PRO B CD  1 
ATOM   1511 N N   . ALA B 1 48  ? -20.93731 -17.21951 -2.46796  1.000 20.01933 ? 48  ALA B N   1 
ATOM   1512 C CA  . ALA B 1 48  ? -20.58824 -15.97978 -3.14360  1.000 19.98307 ? 48  ALA B CA  1 
ATOM   1513 C C   . ALA B 1 48  ? -19.09351 -15.96062 -3.42725  1.000 19.11039 ? 48  ALA B C   1 
ATOM   1514 O O   . ALA B 1 48  ? -18.28926 -16.48915 -2.64952  1.000 20.14772 ? 48  ALA B O   1 
ATOM   1515 C CB  . ALA B 1 48  ? -20.99123 -14.77130 -2.28806  1.000 21.96467 ? 48  ALA B CB  1 
ATOM   1516 N N   . GLY B 1 49  ? -18.72221 -15.36631 -4.55749  1.000 16.77388 ? 49  GLY B N   1 
ATOM   1517 C CA  . GLY B 1 49  ? -17.35316 -15.38192 -5.01862  1.000 16.85028 ? 49  GLY B CA  1 
ATOM   1518 C C   . GLY B 1 49  ? -17.03552 -16.44335 -6.05091  1.000 19.94975 ? 49  GLY B C   1 
ATOM   1519 O O   . GLY B 1 49  ? -15.90813 -16.48038 -6.54205  1.000 16.37527 ? 49  GLY B O   1 
ATOM   1520 N N   . ASN B 1 50  ? -17.98337 -17.31051 -6.39128  1.000 17.51086 ? 50  ASN B N   1 
ATOM   1521 C CA  . ASN B 1 50  ? -17.75596 -18.31067 -7.42909  1.000 15.12830 ? 50  ASN B CA  1 
ATOM   1522 C C   . ASN B 1 50  ? -18.10700 -17.80368 -8.82604  1.000 12.87614 ? 50  ASN B C   1 
ATOM   1523 O O   . ASN B 1 50  ? -17.90096 -18.53260 -9.80478  1.000 13.31152 ? 50  ASN B O   1 
ATOM   1524 C CB  . ASN B 1 50  ? -18.55658 -19.57531 -7.12752  1.000 14.42342 ? 50  ASN B CB  1 
ATOM   1525 C CG  . ASN B 1 50  ? -17.82695 -20.50465 -6.18944  1.000 17.82201 ? 50  ASN B CG  1 
ATOM   1526 O OD1 . ASN B 1 50  ? -16.90310 -20.08685 -5.48741  1.000 16.95325 ? 50  ASN B OD1 1 
ATOM   1527 N ND2 . ASN B 1 50  ? -18.22197 -21.77878 -6.17501  1.000 20.24001 ? 50  ASN B ND2 1 
ATOM   1528 N N   . VAL B 1 51  ? -18.63237 -16.58966 -8.94681  1.000 14.52496 ? 51  VAL B N   1 
ATOM   1529 C CA  . VAL B 1 51  ? -18.98954 -16.00833 -10.24054 1.000 12.97671 ? 51  VAL B CA  1 
ATOM   1530 C C   . VAL B 1 51  ? -17.97439 -14.93953 -10.59655 1.000 15.23131 ? 51  VAL B C   1 
ATOM   1531 O O   . VAL B 1 51  ? -17.69422 -14.04366 -9.78966  1.000 15.81217 ? 51  VAL B O   1 
ATOM   1532 C CB  . VAL B 1 51  ? -20.40281 -15.40389 -10.22646 1.000 14.31239 ? 51  VAL B CB  1 
ATOM   1533 C CG1 . VAL B 1 51  ? -20.70907 -14.78467 -11.57368 1.000 14.05102 ? 51  VAL B CG1 1 
ATOM   1534 C CG2 . VAL B 1 51  ? -21.42902 -16.46941 -9.84222  1.000 17.13082 ? 51  VAL B CG2 1 
ATOM   1535 N N   . PHE B 1 52  ? -17.44251 -15.01161 -11.81251 1.000 13.84645 ? 52  PHE B N   1 
ATOM   1536 C CA  . PHE B 1 52  ? -16.50737 -14.01356 -12.31387 1.000 12.77554 ? 52  PHE B CA  1 
ATOM   1537 C C   . PHE B 1 52  ? -17.08765 -13.41511 -13.57886 1.000 14.07686 ? 52  PHE B C   1 
ATOM   1538 O O   . PHE B 1 52  ? -17.58253 -14.15568 -14.43017 1.000 14.09205 ? 52  PHE B O   1 
ATOM   1539 C CB  . PHE B 1 52  ? -15.14726 -14.62724 -12.60541 1.000 13.37360 ? 52  PHE B CB  1 
ATOM   1540 C CG  . PHE B 1 52  ? -14.41879 -15.06561 -11.37295 1.000 15.67867 ? 52  PHE B CG  1 
ATOM   1541 C CD1 . PHE B 1 52  ? -14.78730 -16.22461 -10.69711 1.000 17.71843 ? 52  PHE B CD1 1 
ATOM   1542 C CD2 . PHE B 1 52  ? -13.41285 -14.28054 -10.85848 1.000 15.33904 ? 52  PHE B CD2 1 
ATOM   1543 C CE1 . PHE B 1 52  ? -14.12889 -16.61242 -9.54368  1.000 16.41983 ? 52  PHE B CE1 1 
ATOM   1544 C CE2 . PHE B 1 52  ? -12.74626 -14.66096 -9.71468  1.000 18.21267 ? 52  PHE B CE2 1 
ATOM   1545 C CZ  . PHE B 1 52  ? -13.10778 -15.81515 -9.05292  1.000 18.48258 ? 52  PHE B CZ  1 
ATOM   1546 N N   . LEU B 1 53  ? -17.05514 -12.08466 -13.68906 1.000 14.02394 ? 53  LEU B N   1 
ATOM   1547 C CA  . LEU B 1 53  ? -17.45215 -11.38258 -14.90182 1.000 11.40151 ? 53  LEU B CA  1 
ATOM   1548 C C   . LEU B 1 53  ? -16.24039 -10.60928 -15.39780 1.000 15.79172 ? 53  LEU B C   1 
ATOM   1549 O O   . LEU B 1 53  ? -15.68673 -9.79036  -14.66048 1.000 16.09569 ? 53  LEU B O   1 
ATOM   1550 C CB  . LEU B 1 53  ? -18.63144 -10.43901 -14.64538 1.000 14.88798 ? 53  LEU B CB  1 
ATOM   1551 C CG  . LEU B 1 53  ? -19.89006 -11.11621 -14.10546 1.000 15.66589 ? 53  LEU B CG  1 
ATOM   1552 C CD1 . LEU B 1 53  ? -21.02732 -10.10940 -13.84041 1.000 15.91636 ? 53  LEU B CD1 1 
ATOM   1553 C CD2 . LEU B 1 53  ? -20.34844 -12.20399 -15.06773 1.000 18.37207 ? 53  LEU B CD2 1 
ATOM   1554 N N   . GLY B 1 54  ? -15.81368 -10.88430 -16.62536 1.000 14.12417 ? 54  GLY B N   1 
ATOM   1555 C CA  . GLY B 1 54  ? -14.59501 -10.27252 -17.12169 1.000 13.37140 ? 54  GLY B CA  1 
ATOM   1556 C C   . GLY B 1 54  ? -13.37575 -10.59870 -16.28840 1.000 17.17587 ? 54  GLY B C   1 
ATOM   1557 O O   . GLY B 1 54  ? -12.41168 -9.82585  -16.27703 1.000 20.51408 ? 54  GLY B O   1 
ATOM   1558 N N   . GLY B 1 55  ? -13.40206 -11.72004 -15.57069 1.000 15.49256 ? 55  GLY B N   1 
ATOM   1559 C CA  . GLY B 1 55  ? -12.35216 -12.06965 -14.63491 1.000 13.90195 ? 55  GLY B CA  1 
ATOM   1560 C C   . GLY B 1 55  ? -12.43580 -11.38677 -13.28630 1.000 20.90502 ? 55  GLY B C   1 
ATOM   1561 O O   . GLY B 1 55  ? -11.52079 -11.55399 -12.47349 1.000 21.23110 ? 55  GLY B O   1 
ATOM   1562 N N   . VAL B 1 56  ? -13.49479 -10.63040 -13.01908 1.000 14.65131 ? 56  VAL B N   1 
ATOM   1563 C CA  . VAL B 1 56  ? -13.65663 -9.89876  -11.76885 1.000 16.71624 ? 56  VAL B CA  1 
ATOM   1564 C C   . VAL B 1 56  ? -14.59220 -10.69008 -10.85828 1.000 18.95852 ? 56  VAL B C   1 
ATOM   1565 O O   . VAL B 1 56  ? -15.73854 -10.98483 -11.21968 1.000 17.22163 ? 56  VAL B O   1 
ATOM   1566 C CB  . VAL B 1 56  ? -14.19294 -8.47737  -12.01817 1.000 18.79081 ? 56  VAL B CB  1 
ATOM   1567 C CG1 . VAL B 1 56  ? -14.55859 -7.79092  -10.69265 1.000 17.56563 ? 56  VAL B CG1 1 
ATOM   1568 C CG2 . VAL B 1 56  ? -13.20069 -7.67344  -12.81830 1.000 16.46821 ? 56  VAL B CG2 1 
ATOM   1569 N N   . GLN B 1 57  ? -14.11361 -11.02204 -9.66501  1.000 18.34537 ? 57  GLN B N   1 
ATOM   1570 C CA  . GLN B 1 57  ? -14.92000 -11.79339 -8.72924  1.000 18.57682 ? 57  GLN B CA  1 
ATOM   1571 C C   . GLN B 1 57  ? -16.15458 -11.00015 -8.30052  1.000 20.45215 ? 57  GLN B C   1 
ATOM   1572 O O   . GLN B 1 57  ? -16.06264 -9.82770  -7.92225  1.000 19.11931 ? 57  GLN B O   1 
ATOM   1573 C CB  . GLN B 1 57  ? -14.06825 -12.17711 -7.51952  1.000 17.83017 ? 57  GLN B CB  1 
ATOM   1574 C CG  . GLN B 1 57  ? -14.79417 -13.01723 -6.48650  1.000 16.95749 ? 57  GLN B CG  1 
ATOM   1575 C CD  . GLN B 1 57  ? -13.88571 -13.38403 -5.32708  1.000 25.84623 ? 57  GLN B CD  1 
ATOM   1576 O OE1 . GLN B 1 57  ? -14.13865 -13.00416 -4.19293  1.000 32.53979 ? 57  GLN B OE1 1 
ATOM   1577 N NE2 . GLN B 1 57  ? -12.80508 -14.09501 -5.61937  1.000 30.01704 ? 57  GLN B NE2 1 
ATOM   1578 N N   . GLN B 1 58  ? -17.31646 -11.64005 -8.36086  1.000 16.07860 ? 58  GLN B N   1 
ATOM   1579 C CA  . GLN B 1 58  ? -18.57495 -10.98690 -8.02542  1.000 16.80282 ? 58  GLN B CA  1 
ATOM   1580 C C   . GLN B 1 58  ? -18.98576 -11.27525 -6.58673  1.000 15.27290 ? 58  GLN B C   1 
ATOM   1581 O O   . GLN B 1 58  ? -18.50502 -12.21871 -5.94887  1.000 18.90751 ? 58  GLN B O   1 
ATOM   1582 C CB  . GLN B 1 58  ? -19.69336 -11.43986 -8.97450  1.000 17.91051 ? 58  GLN B CB  1 
ATOM   1583 C CG  . GLN B 1 58  ? -19.42604 -11.15689 -10.44360 1.000 19.81717 ? 58  GLN B CG  1 
ATOM   1584 C CD  . GLN B 1 58  ? -19.28326 -9.68039  -10.70817 1.000 22.24838 ? 58  GLN B CD  1 
ATOM   1585 O OE1 . GLN B 1 58  ? -20.23420 -8.92587  -10.53361 1.000 22.45560 ? 58  GLN B OE1 1 
ATOM   1586 N NE2 . GLN B 1 58  ? -18.10587 -9.26170  -11.18093 1.000 16.49115 ? 58  GLN B NE2 1 
ATOM   1587 N N   . GLY B 1 59  ? -19.88931 -10.43664 -6.07879  1.000 19.26649 ? 59  GLY B N   1 
ATOM   1588 C CA  . GLY B 1 59  ? -20.53982 -10.67282 -4.80455  1.000 18.18803 ? 59  GLY B CA  1 
ATOM   1589 C C   . GLY B 1 59  ? -21.67795 -11.65598 -4.96559  1.000 22.69697 ? 59  GLY B C   1 
ATOM   1590 O O   . GLY B 1 59  ? -21.64504 -12.53581 -5.82983  1.000 21.71799 ? 59  GLY B O   1 
ATOM   1591 N N   . GLY B 1 60  ? -22.70929 -11.50520 -4.13938  1.000 19.35318 ? 60  GLY B N   1 
ATOM   1592 C CA  . GLY B 1 60  ? -23.82046 -12.43538 -4.14819  1.000 21.15285 ? 60  GLY B CA  1 
ATOM   1593 C C   . GLY B 1 60  ? -25.04824 -12.01727 -4.93097  1.000 20.98856 ? 60  GLY B C   1 
ATOM   1594 O O   . GLY B 1 60  ? -26.09168 -12.66608 -4.79746  1.000 19.67272 ? 60  GLY B O   1 
ATOM   1595 N N   . ASP B 1 61  ? -24.95822 -10.97658 -5.76203  1.000 20.54693 ? 61  ASP B N   1 
ATOM   1596 C CA  . ASP B 1 61  ? -26.10452 -10.38222 -6.43273  1.000 20.83108 ? 61  ASP B CA  1 
ATOM   1597 C C   . ASP B 1 61  ? -26.25793 -10.77430 -7.89662  1.000 25.93971 ? 61  ASP B C   1 
ATOM   1598 O O   . ASP B 1 61  ? -26.97750 -10.09096 -8.62534  1.000 36.59879 ? 61  ASP B O   1 
ATOM   1599 C CB  . ASP B 1 61  ? -26.04325 -8.85483  -6.35422  1.000 27.44432 ? 61  ASP B CB  1 
ATOM   1600 C CG  . ASP B 1 61  ? -27.04212 -8.27836  -5.40408  1.000 39.19607 ? 61  ASP B CG  1 
ATOM   1601 O OD1 . ASP B 1 61  ? -27.42214 -8.96688  -4.43222  1.000 43.79293 ? 61  ASP B OD1 1 
ATOM   1602 O OD2 . ASP B 1 61  ? -27.46623 -7.12687  -5.66763  1.000 37.30579 ? 61  ASP B OD2 1 
ATOM   1603 N N   . THR B 1 62  ? -25.62383 -11.83852 -8.35157  1.000 21.19952 ? 62  THR B N   1 
ATOM   1604 C CA  . THR B 1 62  ? -25.72425 -12.22371 -9.75158  1.000 16.32376 ? 62  THR B CA  1 
ATOM   1605 C C   . THR B 1 62  ? -26.72318 -13.37490 -9.85150  1.000 14.70792 ? 62  THR B C   1 
ATOM   1606 O O   . THR B 1 62  ? -26.78204 -14.21457 -8.95150  1.000 17.17939 ? 62  THR B O   1 
ATOM   1607 C CB  . THR B 1 62  ? -24.34195 -12.64661 -10.27471 1.000 22.88263 ? 62  THR B CB  1 
ATOM   1608 O OG1 . THR B 1 62  ? -23.39809 -11.59485 -10.02006 1.000 32.90811 ? 62  THR B OG1 1 
ATOM   1609 C CG2 . THR B 1 62  ? -24.37565 -12.79256 -11.75758 1.000 25.31574 ? 62  THR B CG2 1 
ATOM   1610 N N   . ILE B 1 63  ? -27.53103 -13.39793 -10.91902 1.000 14.41485 ? 63  ILE B N   1 
ATOM   1611 C CA  . ILE B 1 63  ? -28.41895 -14.52806 -11.19846 1.000 13.08005 ? 63  ILE B CA  1 
ATOM   1612 C C   . ILE B 1 63  ? -28.24494 -14.92677 -12.65725 1.000 14.53218 ? 63  ILE B C   1 
ATOM   1613 O O   . ILE B 1 63  ? -28.28554 -14.07102 -13.54790 1.000 15.74276 ? 63  ILE B O   1 
ATOM   1614 C CB  . ILE B 1 63  ? -29.91236 -14.22703 -10.95448 1.000 15.41815 ? 63  ILE B CB  1 
ATOM   1615 C CG1 . ILE B 1 63  ? -30.22990 -13.85884 -9.51938  1.000 20.59027 ? 63  ILE B CG1 1 
ATOM   1616 C CG2 . ILE B 1 63  ? -30.77571 -15.46785 -11.26000 1.000 13.93152 ? 63  ILE B CG2 1 
ATOM   1617 C CD1 . ILE B 1 63  ? -31.54087 -13.08521 -9.46699  1.000 21.12561 ? 63  ILE B CD1 1 
ATOM   1618 N N   . PHE B 1 64  ? -28.09388 -16.22480 -12.90916 1.000 13.62104 ? 64  PHE B N   1 
ATOM   1619 C CA  . PHE B 1 64  ? -28.08085 -16.75563 -14.26809 1.000 8.92292  ? 64  PHE B CA  1 
ATOM   1620 C C   . PHE B 1 64  ? -29.20696 -17.76924 -14.37153 1.000 12.18692 ? 64  PHE B C   1 
ATOM   1621 O O   . PHE B 1 64  ? -29.29425 -18.67669 -13.54673 1.000 13.33146 ? 64  PHE B O   1 
ATOM   1622 C CB  . PHE B 1 64  ? -26.73175 -17.41633 -14.61900 1.000 12.53542 ? 64  PHE B CB  1 
ATOM   1623 C CG  . PHE B 1 64  ? -26.72388 -18.15351 -15.95005 1.000 13.21938 ? 64  PHE B CG  1 
ATOM   1624 C CD1 . PHE B 1 64  ? -27.30095 -17.60252 -17.08277 1.000 12.37462 ? 64  PHE B CD1 1 
ATOM   1625 C CD2 . PHE B 1 64  ? -26.11145 -19.39467 -16.06090 1.000 10.69422 ? 64  PHE B CD2 1 
ATOM   1626 C CE1 . PHE B 1 64  ? -27.29209 -18.28700 -18.30214 1.000 11.12282 ? 64  PHE B CE1 1 
ATOM   1627 C CE2 . PHE B 1 64  ? -26.10563 -20.08150 -17.27695 1.000 8.49091  ? 64  PHE B CE2 1 
ATOM   1628 C CZ  . PHE B 1 64  ? -26.69319 -19.51431 -18.39352 1.000 9.12001  ? 64  PHE B CZ  1 
ATOM   1629 N N   . VAL B 1 65  ? -30.08896 -17.57202 -15.34221 1.000 11.30505 ? 65  VAL B N   1 
ATOM   1630 C CA  . VAL B 1 65  ? -31.18382 -18.48839 -15.63279 1.000 9.13879  ? 65  VAL B CA  1 
ATOM   1631 C C   . VAL B 1 65  ? -30.83197 -19.20059 -16.92300 1.000 11.41290 ? 65  VAL B C   1 
ATOM   1632 O O   . VAL B 1 65  ? -30.70026 -18.55340 -17.96662 1.000 12.41408 ? 65  VAL B O   1 
ATOM   1633 C CB  . VAL B 1 65  ? -32.52173 -17.75100 -15.78352 1.000 13.29407 ? 65  VAL B CB  1 
ATOM   1634 C CG1 . VAL B 1 65  ? -33.64692 -18.75434 -16.11384 1.000 14.16270 ? 65  VAL B CG1 1 
ATOM   1635 C CG2 . VAL B 1 65  ? -32.83556 -16.95452 -14.51578 1.000 14.72335 ? 65  VAL B CG2 1 
ATOM   1636 N N   . HIS B 1 66  ? -30.69414 -20.52532 -16.85627 1.000 12.22379 ? 66  HIS B N   1 
ATOM   1637 C CA  . HIS B 1 66  ? -30.53448 -21.38454 -18.03369 1.000 10.81505 ? 66  HIS B CA  1 
ATOM   1638 C C   . HIS B 1 66  ? -31.83596 -22.16057 -18.20988 1.000 10.24503 ? 66  HIS B C   1 
ATOM   1639 O O   . HIS B 1 66  ? -32.11785 -23.09708 -17.45540 1.000 11.47777 ? 66  HIS B O   1 
ATOM   1640 C CB  . HIS B 1 66  ? -29.36055 -22.33453 -17.86740 1.000 9.28758  ? 66  HIS B CB  1 
ATOM   1641 C CG  . HIS B 1 66  ? -28.96608 -23.04205 -19.13222 1.000 11.85081 ? 66  HIS B CG  1 
ATOM   1642 N ND1 . HIS B 1 66  ? -28.09939 -24.11147 -19.14065 1.000 9.64852  ? 66  HIS B ND1 1 
ATOM   1643 C CD2 . HIS B 1 66  ? -29.31289 -22.82934 -20.42246 1.000 12.17487 ? 66  HIS B CD2 1 
ATOM   1644 C CE1 . HIS B 1 66  ? -27.94011 -24.54252 -20.38054 1.000 10.00831 ? 66  HIS B CE1 1 
ATOM   1645 N NE2 . HIS B 1 66  ? -28.66413 -23.78093 -21.18005 1.000 11.06951 ? 66  HIS B NE2 1 
ATOM   1646 N N   . GLY B 1 67  ? -32.63674 -21.75397 -19.19048 1.000 9.37239  ? 67  GLY B N   1 
ATOM   1647 C CA  . GLY B 1 67  ? -33.91143 -22.39727 -19.46043 1.000 10.86370 ? 67  GLY B CA  1 
ATOM   1648 C C   . GLY B 1 67  ? -33.75425 -23.41847 -20.57164 1.000 12.04803 ? 67  GLY B C   1 
ATOM   1649 O O   . GLY B 1 67  ? -33.19527 -23.12065 -21.62331 1.000 16.06341 ? 67  GLY B O   1 
ATOM   1650 N N   . LEU B 1 68  ? -34.28654 -24.61787 -20.33297 1.000 9.68024  ? 68  LEU B N   1 
ATOM   1651 C CA  . LEU B 1 68  ? -34.16884 -25.73966 -21.25363 1.000 10.42050 ? 68  LEU B CA  1 
ATOM   1652 C C   . LEU B 1 68  ? -35.58389 -26.04928 -21.72506 1.000 13.09551 ? 68  LEU B C   1 
ATOM   1653 O O   . LEU B 1 68  ? -36.44011 -26.40518 -20.90361 1.000 14.33584 ? 68  LEU B O   1 
ATOM   1654 C CB  . LEU B 1 68  ? -33.53183 -26.94727 -20.56265 1.000 10.01002 ? 68  LEU B CB  1 
ATOM   1655 C CG  . LEU B 1 68  ? -32.16938 -26.64869 -19.90044 1.000 12.53965 ? 68  LEU B CG  1 
ATOM   1656 C CD1 . LEU B 1 68  ? -31.69425 -27.81908 -19.03947 1.000 9.48171  ? 68  LEU B CD1 1 
ATOM   1657 C CD2 . LEU B 1 68  ? -31.14403 -26.32225 -20.98605 1.000 13.07347 ? 68  LEU B CD2 1 
ATOM   1658 N N   . HIS B 1 69  ? -35.82064 -25.90084 -23.03309 1.000 13.32895 ? 69  HIS B N   1 
ATOM   1659 C CA  . HIS B 1 69  ? -37.14611 -25.89123 -23.64962 1.000 12.64936 ? 69  HIS B CA  1 
ATOM   1660 C C   . HIS B 1 69  ? -37.24515 -26.92856 -24.76199 1.000 10.75342 ? 69  HIS B C   1 
ATOM   1661 O O   . HIS B 1 69  ? -36.24003 -27.38430 -25.30500 1.000 12.24567 ? 69  HIS B O   1 
ATOM   1662 C CB  . HIS B 1 69  ? -37.45315 -24.53982 -24.31351 1.000 13.84717 ? 69  HIS B CB  1 
ATOM   1663 C CG  . HIS B 1 69  ? -37.57302 -23.38498 -23.36901 1.000 17.22469 ? 69  HIS B CG  1 
ATOM   1664 N ND1 . HIS B 1 69  ? -37.68672 -22.08551 -23.81603 1.000 21.46060 ? 69  HIS B ND1 1 
ATOM   1665 C CD2 . HIS B 1 69  ? -37.59794 -23.32277 -22.02034 1.000 17.23306 ? 69  HIS B CD2 1 
ATOM   1666 C CE1 . HIS B 1 69  ? -37.77819 -21.27141 -22.77786 1.000 16.22905 ? 69  HIS B CE1 1 
ATOM   1667 N NE2 . HIS B 1 69  ? -37.72381 -21.99680 -21.67549 1.000 15.12737 ? 69  HIS B NE2 1 
ATOM   1668 N N   . ARG B 1 70  ? -38.48152 -27.23044 -25.15539 1.000 9.79727  ? 70  ARG B N   1 
ATOM   1669 C CA  . ARG B 1 70  ? -38.72492 -27.98001 -26.38505 1.000 13.85381 ? 70  ARG B CA  1 
ATOM   1670 C C   . ARG B 1 70  ? -38.49961 -27.07055 -27.58306 1.000 10.27114 ? 70  ARG B C   1 
ATOM   1671 O O   . ARG B 1 70  ? -38.85332 -25.89052 -27.55047 1.000 10.95401 ? 70  ARG B O   1 
ATOM   1672 C CB  . ARG B 1 70  ? -40.17362 -28.46938 -26.41545 1.000 11.42699 ? 70  ARG B CB  1 
ATOM   1673 C CG  . ARG B 1 70  ? -40.43714 -29.63898 -25.49776 1.000 14.58434 ? 70  ARG B CG  1 
ATOM   1674 C CD  . ARG B 1 70  ? -41.92452 -29.95600 -25.45276 1.000 21.06126 ? 70  ARG B CD  1 
ATOM   1675 N NE  . ARG B 1 70  ? -42.58595 -29.08010 -24.48900 1.000 23.50337 ? 70  ARG B NE  1 
ATOM   1676 C CZ  . ARG B 1 70  ? -43.87112 -28.74812 -24.51923 1.000 30.61137 ? 70  ARG B CZ  1 
ATOM   1677 N NH1 . ARG B 1 70  ? -44.71142 -29.30976 -25.37463 1.000 24.94601 ? 70  ARG B NH1 1 
ATOM   1678 N NH2 . ARG B 1 70  ? -44.33198 -27.85194 -23.64569 1.000 27.43345 ? 70  ARG B NH2 1 
ATOM   1679 N N   . GLU B 1 71  ? -37.91404 -27.61817 -28.64547 1.000 10.02047 ? 71  GLU B N   1 
ATOM   1680 C CA  . GLU B 1 71  ? -37.93358 -26.94959 -29.94231 1.000 13.00230 ? 71  GLU B CA  1 
ATOM   1681 C C   . GLU B 1 71  ? -39.36478 -26.64970 -30.36840 1.000 15.33172 ? 71  GLU B C   1 
ATOM   1682 O O   . GLU B 1 71  ? -40.30596 -27.38155 -30.03091 1.000 13.27197 ? 71  GLU B O   1 
ATOM   1683 C CB  . GLU B 1 71  ? -37.28538 -27.83385 -31.01208 1.000 14.76875 ? 71  GLU B CB  1 
ATOM   1684 C CG  . GLU B 1 71  ? -35.79100 -27.71101 -31.13242 1.000 22.66906 ? 71  GLU B CG  1 
ATOM   1685 C CD  . GLU B 1 71  ? -35.18303 -28.84528 -31.95287 1.000 24.03521 ? 71  GLU B CD  1 
ATOM   1686 O OE1 . GLU B 1 71  ? -35.94082 -29.57411 -32.63280 1.000 23.55241 ? 71  GLU B OE1 1 
ATOM   1687 O OE2 . GLU B 1 71  ? -33.94905 -29.01976 -31.88846 1.000 28.39490 ? 71  GLU B OE2 1 
ATOM   1688 N N   . GLY B 1 72  ? -39.52472 -25.57870 -31.14399 1.000 11.61051 ? 72  GLY B N   1 
ATOM   1689 C CA  . GLY B 1 72  ? -40.80363 -25.35508 -31.79941 1.000 17.43162 ? 72  GLY B CA  1 
ATOM   1690 C C   . GLY B 1 72  ? -41.46016 -24.00033 -31.63089 1.000 14.44253 ? 72  GLY B C   1 
ATOM   1691 O O   . GLY B 1 72  ? -42.46999 -23.72280 -32.28773 1.000 13.42221 ? 72  GLY B O   1 
ATOM   1692 N N   . ARG B 1 73  ? -40.91701 -23.13930 -30.77637 1.000 12.05454 ? 73  ARG B N   1 
ATOM   1693 C CA  . ARG B 1 73  ? -41.51237 -21.82614 -30.57462 1.000 10.42128 ? 73  ARG B CA  1 
ATOM   1694 C C   . ARG B 1 73  ? -40.76313 -20.77530 -31.38806 1.000 14.02661 ? 73  ARG B C   1 
ATOM   1695 O O   . ARG B 1 73  ? -39.62096 -20.97328 -31.81619 1.000 14.01663 ? 73  ARG B O   1 
ATOM   1696 C CB  . ARG B 1 73  ? -41.50465 -21.44892 -29.08971 1.000 17.05458 ? 73  ARG B CB  1 
ATOM   1697 C CG  . ARG B 1 73  ? -42.13803 -22.50582 -28.20392 1.000 22.04886 ? 73  ARG B CG  1 
ATOM   1698 C CD  . ARG B 1 73  ? -42.77961 -21.94828 -26.93097 1.000 23.72311 ? 73  ARG B CD  1 
ATOM   1699 N NE  . ARG B 1 73  ? -43.44898 -23.02545 -26.20189 1.000 20.62020 ? 73  ARG B NE  1 
ATOM   1700 C CZ  . ARG B 1 73  ? -42.81007 -23.88339 -25.41869 1.000 29.33321 ? 73  ARG B CZ  1 
ATOM   1701 N NH1 . ARG B 1 73  ? -41.50262 -23.78829 -25.21262 1.000 27.45021 ? 73  ARG B NH1 1 
ATOM   1702 N NH2 . ARG B 1 73  ? -43.49357 -24.86551 -24.83225 1.000 27.85016 ? 73  ARG B NH2 1 
ATOM   1703 N N   . SER B 1 74  ? -41.44514 -19.66140 -31.62486 1.000 12.06908 ? 74  SER B N   1 
ATOM   1704 C CA  . SER B 1 74  ? -40.92383 -18.57546 -32.44272 1.000 11.20178 ? 74  SER B CA  1 
ATOM   1705 C C   . SER B 1 74  ? -39.87239 -17.78250 -31.68465 1.000 14.49543 ? 74  SER B C   1 
ATOM   1706 O O   . SER B 1 74  ? -39.87768 -17.73086 -30.44987 1.000 13.10235 ? 74  SER B O   1 
ATOM   1707 C CB  . SER B 1 74  ? -42.07089 -17.66269 -32.87239 1.000 11.10608 ? 74  SER B CB  1 
ATOM   1708 O OG  . SER B 1 74  ? -42.46667 -16.82933 -31.79925 1.000 15.52681 ? 74  SER B OG  1 
ATOM   1709 N N   . ALA B 1 75  ? -38.94934 -17.16504 -32.43937 1.000 14.35447 ? 75  ALA B N   1 
ATOM   1710 C CA  . ALA B 1 75  ? -37.98159 -16.27250 -31.80523 1.000 11.71608 ? 75  ALA B CA  1 
ATOM   1711 C C   . ALA B 1 75  ? -38.68844 -15.11964 -31.10461 1.000 13.98356 ? 75  ALA B C   1 
ATOM   1712 O O   . ALA B 1 75  ? -38.25616 -14.67136 -30.03337 1.000 11.79185 ? 75  ALA B O   1 
ATOM   1713 C CB  . ALA B 1 75  ? -36.97837 -15.74537 -32.83652 1.000 12.21793 ? 75  ALA B CB  1 
ATOM   1714 N N   . ASP B 1 76  ? -39.79443 -14.64137 -31.69081 1.000 14.41192 ? 76  ASP B N   1 
ATOM   1715 C CA  . ASP B 1 76  ? -40.58699 -13.57531 -31.08043 1.000 13.25623 ? 76  ASP B CA  1 
ATOM   1716 C C   . ASP B 1 76  ? -41.06929 -13.96723 -29.68902 1.000 13.46835 ? 76  ASP B C   1 
ATOM   1717 O O   . ASP B 1 76  ? -40.95212 -13.19039 -28.73739 1.000 15.73536 ? 76  ASP B O   1 
ATOM   1718 C CB  . ASP B 1 76  ? -41.76508 -13.23633 -32.00954 1.000 17.21884 ? 76  ASP B CB  1 
ATOM   1719 C CG  . ASP B 1 76  ? -42.72659 -12.20087 -31.41387 1.000 26.96761 ? 76  ASP B CG  1 
ATOM   1720 O OD1 . ASP B 1 76  ? -42.28356 -11.27053 -30.72473 1.000 29.85686 ? 76  ASP B OD1 1 
ATOM   1721 O OD2 . ASP B 1 76  ? -43.94441 -12.31102 -31.66875 1.000 39.66485 ? 76  ASP B OD2 1 
ATOM   1722 N N   . LEU B 1 77  ? -41.62261 -15.17083 -29.55467 1.000 11.68874 ? 77  LEU B N   1 
ATOM   1723 C CA  . LEU B 1 77  ? -42.17044 -15.59628 -28.27463 1.000 11.97933 ? 77  LEU B CA  1 
ATOM   1724 C C   . LEU B 1 77  ? -41.05650 -15.87829 -27.27093 1.000 13.10222 ? 77  LEU B C   1 
ATOM   1725 O O   . LEU B 1 77  ? -41.18824 -15.55728 -26.08772 1.000 13.30726 ? 77  LEU B O   1 
ATOM   1726 C CB  . LEU B 1 77  ? -43.04349 -16.83683 -28.48512 1.000 16.59864 ? 77  LEU B CB  1 
ATOM   1727 C CG  . LEU B 1 77  ? -43.92147 -17.36615 -27.34548 1.000 20.84671 ? 77  LEU B CG  1 
ATOM   1728 C CD1 . LEU B 1 77  ? -43.19717 -18.39666 -26.49573 1.000 27.25198 ? 77  LEU B CD1 1 
ATOM   1729 C CD2 . LEU B 1 77  ? -44.47856 -16.20551 -26.52180 1.000 22.45927 ? 77  LEU B CD2 1 
ATOM   1730 N N   . LYS B 1 78  ? -39.95666 -16.49985 -27.72059 1.000 13.18411 ? 78  LYS B N   1 
ATOM   1731 C CA  . LYS B 1 78  ? -38.82508 -16.73444 -26.82490 1.000 13.96467 ? 78  LYS B CA  1 
ATOM   1732 C C   . LYS B 1 78  ? -38.26524 -15.41681 -26.30165 1.000 13.62818 ? 78  LYS B C   1 
ATOM   1733 O O   . LYS B 1 78  ? -37.87026 -15.31833 -25.13738 1.000 11.56641 ? 78  LYS B O   1 
ATOM   1734 C CB  . LYS B 1 78  ? -37.73902 -17.54413 -27.53968 1.000 12.49720 ? 78  LYS B CB  1 
ATOM   1735 C CG  . LYS B 1 78  ? -38.10717 -19.02657 -27.70921 1.000 11.21404 ? 78  LYS B CG  1 
ATOM   1736 C CD  . LYS B 1 78  ? -37.00920 -19.83036 -28.42827 1.000 13.11338 ? 78  LYS B CD  1 
ATOM   1737 C CE  . LYS B 1 78  ? -36.96861 -19.50956 -29.92859 1.000 14.23514 ? 78  LYS B CE  1 
ATOM   1738 N NZ  . LYS B 1 78  ? -35.91286 -20.30637 -30.67203 1.000 11.45596 ? 78  LYS B NZ  1 
ATOM   1739 N N   . GLY B 1 79  ? -38.25229 -14.38422 -27.13930 1.000 10.75713 ? 79  GLY B N   1 
ATOM   1740 C CA  . GLY B 1 79  ? -37.80062 -13.07945 -26.67819 1.000 13.27440 ? 79  GLY B CA  1 
ATOM   1741 C C   . GLY B 1 79  ? -38.72276 -12.47687 -25.63528 1.000 12.73658 ? 79  GLY B C   1 
ATOM   1742 O O   . GLY B 1 79  ? -38.26070 -11.95360 -24.61222 1.000 11.85238 ? 79  GLY B O   1 
ATOM   1743 N N   . GLN B 1 80  ? -40.03531 -12.56008 -25.86308 1.000 13.31405 ? 80  GLN B N   1 
ATOM   1744 C CA  . GLN B 1 80  ? -40.98398 -12.04795 -24.87633 1.000 13.28472 ? 80  GLN B CA  1 
ATOM   1745 C C   . GLN B 1 80  ? -40.83787 -12.77537 -23.55648 1.000 14.47276 ? 80  GLN B C   1 
ATOM   1746 O O   . GLN B 1 80  ? -40.96270 -12.16610 -22.48076 1.000 14.64408 ? 80  GLN B O   1 
ATOM   1747 C CB  . GLN B 1 80  ? -42.41895 -12.21285 -25.37067 1.000 16.40471 ? 80  GLN B CB  1 
ATOM   1748 C CG  . GLN B 1 80  ? -42.76257 -11.46900 -26.63310 1.000 17.42374 ? 80  GLN B CG  1 
ATOM   1749 C CD  . GLN B 1 80  ? -44.18467 -11.75448 -27.04275 1.000 26.57762 ? 80  GLN B CD  1 
ATOM   1750 O OE1 . GLN B 1 80  ? -45.08314 -11.79313 -26.19613 1.000 29.47896 ? 80  GLN B OE1 1 
ATOM   1751 N NE2 . GLN B 1 80  ? -44.39917 -11.99494 -28.33143 1.000 25.93474 ? 80  GLN B NE2 1 
ATOM   1752 N N   . LEU B 1 81  ? -40.60221 -14.09392 -23.62837 1.000 12.11846 ? 81  LEU B N   1 
ATOM   1753 C CA  . LEU B 1 81  ? -40.49922 -14.91812 -22.43401 1.000 13.56825 ? 81  LEU B CA  1 
ATOM   1754 C C   . LEU B 1 81  ? -39.20220 -14.62337 -21.68895 1.000 13.64547 ? 81  LEU B C   1 
ATOM   1755 O O   . LEU B 1 81  ? -39.20104 -14.50567 -20.46126 1.000 14.65935 ? 81  LEU B O   1 
ATOM   1756 C CB  . LEU B 1 81  ? -40.59578 -16.39840 -22.81831 1.000 12.91219 ? 81  LEU B CB  1 
ATOM   1757 C CG  . LEU B 1 81  ? -40.46735 -17.43144 -21.69603 1.000 15.12500 ? 81  LEU B CG  1 
ATOM   1758 C CD1 . LEU B 1 81  ? -41.40729 -17.09536 -20.55552 1.000 13.89248 ? 81  LEU B CD1 1 
ATOM   1759 C CD2 . LEU B 1 81  ? -40.69365 -18.87636 -22.23465 1.000 15.16204 ? 81  LEU B CD2 1 
ATOM   1760 N N   . ALA B 1 82  ? -38.09102 -14.46984 -22.41036 1.000 11.18418 ? 82  ALA B N   1 
ATOM   1761 C CA  . ALA B 1 82  ? -36.85353 -14.08567 -21.72551 1.000 11.38125 ? 82  ALA B CA  1 
ATOM   1762 C C   . ALA B 1 82  ? -36.98444 -12.71766 -21.07387 1.000 13.98241 ? 82  ALA B C   1 
ATOM   1763 O O   . ALA B 1 82  ? -36.50819 -12.50715 -19.95114 1.000 15.89477 ? 82  ALA B O   1 
ATOM   1764 C CB  . ALA B 1 82  ? -35.67350 -14.07507 -22.69645 1.000 10.66059 ? 82  ALA B CB  1 
ATOM   1765 N N   . GLN B 1 83  ? -37.59880 -11.76453 -21.77651 1.000 12.66061 ? 83  GLN B N   1 
ATOM   1766 C CA  . GLN B 1 83  ? -37.77202 -10.43418 -21.20487 1.000 14.69502 ? 83  GLN B CA  1 
ATOM   1767 C C   . GLN B 1 83  ? -38.66922 -10.48578 -19.97257 1.000 17.23782 ? 83  GLN B C   1 
ATOM   1768 O O   . GLN B 1 83  ? -38.40386 -9.80818  -18.97255 1.000 17.57636 ? 83  GLN B O   1 
ATOM   1769 C CB  . GLN B 1 83  ? -38.34780 -9.47178  -22.24651 1.000 13.13207 ? 83  GLN B CB  1 
ATOM   1770 C CG  . GLN B 1 83  ? -38.46236 -8.03787  -21.71343 1.000 18.81515 ? 83  GLN B CG  1 
ATOM   1771 C CD  . GLN B 1 83  ? -37.09708 -7.42059  -21.43225 1.000 18.27832 ? 83  GLN B CD  1 
ATOM   1772 O OE1 . GLN B 1 83  ? -36.29914 -7.23615  -22.34540 1.000 20.10919 ? 83  GLN B OE1 1 
ATOM   1773 N NE2 . GLN B 1 83  ? -36.80928 -7.13752  -20.15953 1.000 21.63248 ? 83  GLN B NE2 1 
ATOM   1774 N N   . ARG B 1 84  ? -39.71884 -11.31055 -20.00476 1.000 17.23156 ? 84  ARG B N   1 
ATOM   1775 C CA  . ARG B 1 84  ? -40.60635 -11.32959 -18.85147 1.000 16.87742 ? 84  ARG B CA  1 
ATOM   1776 C C   . ARG B 1 84  ? -39.93598 -12.01151 -17.66477 1.000 13.69360 ? 84  ARG B C   1 
ATOM   1777 O O   . ARG B 1 84  ? -40.18308 -11.64269 -16.50847 1.000 17.33962 ? 84  ARG B O   1 
ATOM   1778 C CB  . ARG B 1 84  ? -41.92924 -12.01287 -19.19327 1.000 14.80260 ? 84  ARG B CB  1 
ATOM   1779 C CG  . ARG B 1 84  ? -42.79184 -12.14372 -17.96935 1.000 16.75130 ? 84  ARG B CG  1 
ATOM   1780 C CD  . ARG B 1 84  ? -44.18884 -12.57082 -18.29663 1.000 25.86220 ? 84  ARG B CD  1 
ATOM   1781 N NE  . ARG B 1 84  ? -44.86992 -13.01262 -17.08629 1.000 33.33917 ? 84  ARG B NE  1 
ATOM   1782 C CZ  . ARG B 1 84  ? -46.12953 -13.42587 -17.04857 1.000 33.56415 ? 84  ARG B CZ  1 
ATOM   1783 N NH1 . ARG B 1 84  ? -46.86601 -13.49296 -18.14947 1.000 33.09474 ? 84  ARG B NH1 1 
ATOM   1784 N NH2 . ARG B 1 84  ? -46.65999 -13.78122 -15.87939 1.000 30.07085 ? 84  ARG B NH2 1 
ATOM   1785 N N   . ILE B 1 85  ? -39.06260 -12.98394 -17.92280 1.000 13.08441 ? 85  ILE B N   1 
ATOM   1786 C CA  . ILE B 1 85  ? -38.29492 -13.56378 -16.82496 1.000 15.61529 ? 85  ILE B CA  1 
ATOM   1787 C C   . ILE B 1 85  ? -37.36943 -12.51766 -16.22633 1.000 14.59214 ? 85  ILE B C   1 
ATOM   1788 O O   . ILE B 1 85  ? -37.27084 -12.38788 -15.00209 1.000 14.48963 ? 85  ILE B O   1 
ATOM   1789 C CB  . ILE B 1 85  ? -37.52776 -14.81114 -17.29908 1.000 11.40083 ? 85  ILE B CB  1 
ATOM   1790 C CG1 . ILE B 1 85  ? -38.50883 -15.96679 -17.45613 1.000 14.79129 ? 85  ILE B CG1 1 
ATOM   1791 C CG2 . ILE B 1 85  ? -36.46563 -15.20926 -16.27409 1.000 13.56567 ? 85  ILE B CG2 1 
ATOM   1792 C CD1 . ILE B 1 85  ? -37.91885 -17.15983 -18.13997 1.000 16.68201 ? 85  ILE B CD1 1 
ATOM   1793 N N   . VAL B 1 86  ? -36.71793 -11.71996 -17.07292 1.000 10.62868 ? 86  VAL B N   1 
ATOM   1794 C CA  . VAL B 1 86  ? -35.85809 -10.65591 -16.55887 1.000 14.95547 ? 86  VAL B CA  1 
ATOM   1795 C C   . VAL B 1 86  ? -36.67276 -9.71197  -15.68013 1.000 14.74632 ? 86  VAL B C   1 
ATOM   1796 O O   . VAL B 1 86  ? -36.32264 -9.45156  -14.52313 1.000 14.70057 ? 86  VAL B O   1 
ATOM   1797 C CB  . VAL B 1 86  ? -35.17072 -9.90425  -17.71683 1.000 13.36087 ? 86  VAL B CB  1 
ATOM   1798 C CG1 . VAL B 1 86  ? -34.45391 -8.67061  -17.20031 1.000 16.19179 ? 86  VAL B CG1 1 
ATOM   1799 C CG2 . VAL B 1 86  ? -34.17855 -10.79301 -18.43685 1.000 13.47683 ? 86  VAL B CG2 1 
ATOM   1800 N N   . ASP B 1 87  ? -37.80230 -9.22614  -16.20103 1.000 14.18563 ? 87  ASP B N   1 
ATOM   1801 C CA  . ASP B 1 87  ? -38.59894 -8.24827  -15.45802 1.000 18.58495 ? 87  ASP B CA  1 
ATOM   1802 C C   . ASP B 1 87  ? -39.13957 -8.83672  -14.16075 1.000 21.33343 ? 87  ASP B C   1 
ATOM   1803 O O   . ASP B 1 87  ? -39.06298 -8.20595  -13.09723 1.000 16.16750 ? 87  ASP B O   1 
ATOM   1804 C CB  . ASP B 1 87  ? -39.76237 -7.73538  -16.30607 1.000 17.30574 ? 87  ASP B CB  1 
ATOM   1805 C CG  . ASP B 1 87  ? -39.31054 -6.97107  -17.53630 1.000 26.07380 ? 87  ASP B CG  1 
ATOM   1806 O OD1 . ASP B 1 87  ? -38.17364 -6.45722  -17.56458 1.000 25.29322 ? 87  ASP B OD1 1 
ATOM   1807 O OD2 . ASP B 1 87  ? -40.12920 -6.84894  -18.46971 1.000 23.05100 ? 87  ASP B OD2 1 
ATOM   1808 N N   . ASP B 1 88  ? -39.71056 -10.03959 -14.22994 1.000 14.94970 ? 88  ASP B N   1 
ATOM   1809 C CA  . ASP B 1 88  ? -40.40958 -10.58232 -13.07397 1.000 15.39335 ? 88  ASP B CA  1 
ATOM   1810 C C   . ASP B 1 88  ? -39.46484 -11.17662 -12.03805 1.000 18.48499 ? 88  ASP B C   1 
ATOM   1811 O O   . ASP B 1 88  ? -39.77479 -11.13126 -10.84229 1.000 18.53954 ? 88  ASP B O   1 
ATOM   1812 C CB  . ASP B 1 88  ? -41.44478 -11.60906 -13.52374 1.000 16.06504 ? 88  ASP B CB  1 
ATOM   1813 C CG  . ASP B 1 88  ? -42.60053 -10.97120 -14.29836 1.000 23.84877 ? 88  ASP B CG  1 
ATOM   1814 O OD1 . ASP B 1 88  ? -42.61775 -9.72612  -14.44956 1.000 25.46425 ? 88  ASP B OD1 1 
ATOM   1815 O OD2 . ASP B 1 88  ? -43.48932 -11.71001 -14.76045 1.000 25.52321 ? 88  ASP B OD2 1 
ATOM   1816 N N   . VAL B 1 89  ? -38.31418 -11.72042 -12.45135 1.000 12.90823 ? 89  VAL B N   1 
ATOM   1817 C CA  . VAL B 1 89  ? -37.31981 -12.13202 -11.45727 1.000 13.17192 ? 89  VAL B CA  1 
ATOM   1818 C C   . VAL B 1 89  ? -36.72506 -10.91029 -10.76429 1.000 12.82919 ? 89  VAL B C   1 
ATOM   1819 O O   . VAL B 1 89  ? -36.44481 -10.93496 -9.55877  1.000 15.32361 ? 89  VAL B O   1 
ATOM   1820 C CB  . VAL B 1 89  ? -36.23560 -13.01059 -12.10482 1.000 13.31826 ? 89  VAL B CB  1 
ATOM   1821 C CG1 . VAL B 1 89  ? -35.02492 -13.16675 -11.16735 1.000 14.65843 ? 89  VAL B CG1 1 
ATOM   1822 C CG2 . VAL B 1 89  ? -36.81015 -14.37825 -12.41991 1.000 17.28417 ? 89  VAL B CG2 1 
ATOM   1823 N N   . SER B 1 90  ? -36.54507 -9.81674  -11.50534 1.000 13.86014 ? 90  SER B N   1 
ATOM   1824 C CA  . SER B 1 90  ? -36.03433 -8.59038  -10.89736 1.000 15.33473 ? 90  SER B CA  1 
ATOM   1825 C C   . SER B 1 90  ? -36.91402 -8.14585  -9.73732  1.000 16.92307 ? 90  SER B C   1 
ATOM   1826 O O   . SER B 1 90  ? -36.41069 -7.80746  -8.65656  1.000 17.23445 ? 90  SER B O   1 
ATOM   1827 C CB  . SER B 1 90  ? -35.94467 -7.48774  -11.94512 1.000 18.93179 ? 90  SER B CB  1 
ATOM   1828 O OG  . SER B 1 90  ? -35.48944 -6.29578  -11.33868 1.000 23.47329 ? 90  SER B OG  1 
ATOM   1829 N N   . VAL B 1 91  ? -38.22871 -8.17500  -9.93475  1.000 15.10247 ? 91  VAL B N   1 
ATOM   1830 C CA  . VAL B 1 91  ? -39.16453 -7.81137  -8.87396  1.000 17.93464 ? 91  VAL B CA  1 
ATOM   1831 C C   . VAL B 1 91  ? -39.12433 -8.84490  -7.74745  1.000 21.45705 ? 91  VAL B C   1 
ATOM   1832 O O   . VAL B 1 91  ? -38.93552 -8.50432  -6.56903  1.000 16.70737 ? 91  VAL B O   1 
ATOM   1833 C CB  . VAL B 1 91  ? -40.58149 -7.66908  -9.46253  1.000 19.57365 ? 91  VAL B CB  1 
ATOM   1834 C CG1 . VAL B 1 91  ? -41.64447 -7.68244  -8.35291  1.000 27.13498 ? 91  VAL B CG1 1 
ATOM   1835 C CG2 . VAL B 1 91  ? -40.68032 -6.44089  -10.35319 1.000 22.42992 ? 91  VAL B CG2 1 
ATOM   1836 N N   . ALA B 1 92  ? -39.27218 -10.13117 -8.09576  1.000 18.85241 ? 92  ALA B N   1 
ATOM   1837 C CA  . ALA B 1 92  ? -39.40718 -11.17489 -7.07639  1.000 17.05254 ? 92  ALA B CA  1 
ATOM   1838 C C   . ALA B 1 92  ? -38.15037 -11.30370 -6.22248  1.000 22.30060 ? 92  ALA B C   1 
ATOM   1839 O O   . ALA B 1 92  ? -38.23375 -11.52021 -5.00441  1.000 19.81707 ? 92  ALA B O   1 
ATOM   1840 C CB  . ALA B 1 92  ? -39.74449 -12.51399 -7.73885  1.000 16.35430 ? 92  ALA B CB  1 
ATOM   1841 N N   . ALA B 1 93  ? -36.97446 -11.18387 -6.83440  1.000 17.15033 ? 93  ALA B N   1 
ATOM   1842 C CA  . ALA B 1 93  ? -35.73303 -11.30253 -6.08909  1.000 14.22557 ? 93  ALA B CA  1 
ATOM   1843 C C   . ALA B 1 93  ? -35.21523 -9.96384  -5.58864  1.000 17.66808 ? 93  ALA B C   1 
ATOM   1844 O O   . ALA B 1 93  ? -34.18935 -9.94371  -4.90496  1.000 18.30353 ? 93  ALA B O   1 
ATOM   1845 C CB  . ALA B 1 93  ? -34.65757 -11.98095 -6.94125  1.000 16.86732 ? 93  ALA B CB  1 
ATOM   1846 N N   . GLU B 1 94  ? -35.89257 -8.86140  -5.91885  1.000 15.06890 ? 94  GLU B N   1 
ATOM   1847 C CA  . GLU B 1 94  ? -35.43827 -7.50480  -5.59137  1.000 19.83768 ? 94  GLU B CA  1 
ATOM   1848 C C   . GLU B 1 94  ? -33.99288 -7.30541  -6.03227  1.000 22.77275 ? 94  GLU B C   1 
ATOM   1849 O O   . GLU B 1 94  ? -33.11521 -6.96281  -5.23624  1.000 18.53897 ? 94  GLU B O   1 
ATOM   1850 C CB  . GLU B 1 94  ? -35.59182 -7.21258  -4.10020  1.000 24.08735 ? 94  GLU B CB  1 
ATOM   1851 C CG  . GLU B 1 94  ? -36.86791 -7.75575  -3.51086  1.000 29.71299 ? 94  GLU B CG  1 
ATOM   1852 C CD  . GLU B 1 94  ? -37.05222 -7.37859  -2.05291  1.000 41.72751 ? 94  GLU B CD  1 
ATOM   1853 O OE1 . GLU B 1 94  ? -36.55688 -6.31057  -1.63128  1.000 39.72502 ? 94  GLU B OE1 1 
ATOM   1854 O OE2 . GLU B 1 94  ? -37.68813 -8.16964  -1.32707  1.000 34.54596 ? 94  GLU B OE2 1 
ATOM   1855 N N   . ILE B 1 95  ? -33.74137 -7.57286  -7.31454  1.000 20.61508 ? 95  ILE B N   1 
ATOM   1856 C CA  . ILE B 1 95  ? -32.40977 -7.48701  -7.90253  1.000 16.30213 ? 95  ILE B CA  1 
ATOM   1857 C C   . ILE B 1 95  ? -32.48727 -6.65831  -9.16772  1.000 20.37688 ? 95  ILE B C   1 
ATOM   1858 O O   . ILE B 1 95  ? -33.40414 -6.82699  -9.97862  1.000 20.97207 ? 95  ILE B O   1 
ATOM   1859 C CB  . ILE B 1 95  ? -31.80076 -8.87206  -8.21754  1.000 21.55621 ? 95  ILE B CB  1 
ATOM   1860 C CG1 . ILE B 1 95  ? -32.00783 -9.80834  -7.04381  1.000 27.99929 ? 95  ILE B CG1 1 
ATOM   1861 C CG2 . ILE B 1 95  ? -30.32077 -8.77583  -8.52117  1.000 23.28747 ? 95  ILE B CG2 1 
ATOM   1862 C CD1 . ILE B 1 95  ? -31.06145 -10.96636 -6.99074  1.000 30.67408 ? 95  ILE B CD1 1 
ATOM   1863 N N   . ASP B 1 96  ? -31.50694 -5.78146  -9.35087  1.000 17.73491 ? 96  ASP B N   1 
ATOM   1864 C CA  . ASP B 1 96  ? -31.53484 -4.91032  -10.51181 1.000 17.66812 ? 96  ASP B CA  1 
ATOM   1865 C C   . ASP B 1 96  ? -31.35139 -5.75928  -11.76709 1.000 19.08335 ? 96  ASP B C   1 
ATOM   1866 O O   . ASP B 1 96  ? -30.60258 -6.74408  -11.77088 1.000 15.83691 ? 96  ASP B O   1 
ATOM   1867 C CB  . ASP B 1 96  ? -30.42529 -3.87013  -10.42580 1.000 17.69734 ? 96  ASP B CB  1 
ATOM   1868 C CG  . ASP B 1 96  ? -30.46652 -2.87158  -11.57655 1.000 26.06364 ? 96  ASP B CG  1 
ATOM   1869 O OD1 . ASP B 1 96  ? -29.84313 -3.10459  -12.63349 1.000 25.49151 ? 96  ASP B OD1 1 
ATOM   1870 O OD2 . ASP B 1 96  ? -31.09217 -1.80366  -11.39766 1.000 35.22576 ? 96  ASP B OD2 1 
ATOM   1871 N N   . ARG B 1 97  ? -32.01683 -5.34385  -12.84964 1.000 15.24338 ? 97  ARG B N   1 
ATOM   1872 C CA  . ARG B 1 97  ? -32.02773 -6.13214  -14.07854 1.000 17.71868 ? 97  ARG B CA  1 
ATOM   1873 C C   . ARG B 1 97  ? -30.64162 -6.31670  -14.66768 1.000 18.67125 ? 97  ARG B C   1 
ATOM   1874 O O   . ARG B 1 97  ? -30.40058 -7.31000  -15.36978 1.000 16.02962 ? 97  ARG B O   1 
ATOM   1875 C CB  . ARG B 1 97  ? -32.93687 -5.46665  -15.11067 1.000 19.58048 ? 97  ARG B CB  1 
ATOM   1876 C CG  . ARG B 1 97  ? -34.38207 -5.38645  -14.64314 1.000 24.80726 ? 97  ARG B CG  1 
ATOM   1877 C CD  . ARG B 1 97  ? -35.32300 -5.79796  -15.74635 1.000 34.61699 ? 97  ARG B CD  1 
ATOM   1878 N NE  . ARG B 1 97  ? -35.88020 -4.66716  -16.47141 1.000 40.72599 ? 97  ARG B NE  1 
ATOM   1879 C CZ  . ARG B 1 97  ? -36.89018 -3.93364  -16.02657 1.000 44.95166 ? 97  ARG B CZ  1 
ATOM   1880 N NH1 . ARG B 1 97  ? -37.50282 -4.22151  -14.88678 1.000 37.79118 ? 97  ARG B NH1 1 
ATOM   1881 N NH2 . ARG B 1 97  ? -37.30811 -2.89798  -16.75098 1.000 45.36227 ? 97  ARG B NH2 1 
ATOM   1882 N N   A LYS B 1 98  ? -29.72916 -5.36832  -14.41051 0.437 16.62606 ? 98  LYS B N   1 
ATOM   1883 N N   B LYS B 1 98  ? -29.72408 -5.37714  -14.43191 0.563 16.61267 ? 98  LYS B N   1 
ATOM   1884 C CA  A LYS B 1 98  ? -28.34878 -5.47649  -14.87301 0.437 14.35129 ? 98  LYS B CA  1 
ATOM   1885 C CA  B LYS B 1 98  ? -28.38484 -5.54650  -14.97935 0.563 14.22553 ? 98  LYS B CA  1 
ATOM   1886 C C   A LYS B 1 98  ? -27.65587 -6.71983  -14.33780 0.437 16.12946 ? 98  LYS B C   1 
ATOM   1887 C C   B LYS B 1 98  ? -27.62153 -6.68856  -14.31275 0.563 16.09377 ? 98  LYS B C   1 
ATOM   1888 O O   A LYS B 1 98  ? -26.63799 -7.14122  -14.89535 0.437 15.86521 ? 98  LYS B O   1 
ATOM   1889 O O   B LYS B 1 98  ? -26.52520 -7.02331  -14.76909 0.563 15.95477 ? 98  LYS B O   1 
ATOM   1890 C CB  A LYS B 1 98  ? -27.54191 -4.23576  -14.45960 0.437 19.62068 ? 98  LYS B CB  1 
ATOM   1891 C CB  B LYS B 1 98  ? -27.60002 -4.22980  -14.87466 0.563 19.82586 ? 98  LYS B CB  1 
ATOM   1892 C CG  A LYS B 1 98  ? -27.03476 -4.25042  -12.99823 0.437 22.06641 ? 98  LYS B CG  1 
ATOM   1893 C CG  B LYS B 1 98  ? -27.01058 -3.95290  -13.50493 0.563 21.99536 ? 98  LYS B CG  1 
ATOM   1894 C CD  A LYS B 1 98  ? -26.81942 -2.83156  -12.43346 0.437 22.51437 ? 98  LYS B CD  1 
ATOM   1895 C CD  B LYS B 1 98  ? -26.71802 -2.46064  -13.24185 0.563 22.72427 ? 98  LYS B CD  1 
ATOM   1896 C CE  A LYS B 1 98  ? -27.14794 -2.72866  -10.94147 0.437 21.92089 ? 98  LYS B CE  1 
ATOM   1897 C CE  B LYS B 1 98  ? -27.23802 -1.53404  -14.33184 0.563 17.14200 ? 98  LYS B CE  1 
ATOM   1898 N NZ  A LYS B 1 98  ? -26.53146 -1.53696  -10.29297 0.437 24.37266 ? 98  LYS B NZ  1 
ATOM   1899 N NZ  B LYS B 1 98  ? -28.30148 -0.68560  -13.71119 0.563 20.28894 ? 98  LYS B NZ  1 
ATOM   1900 N N   . HIS B 1 99  ? -28.17961 -7.31116  -13.27419 1.000 14.97813 ? 99  HIS B N   1 
ATOM   1901 C CA  . HIS B 1 99  ? -27.56689 -8.47644  -12.64799 1.000 15.51366 ? 99  HIS B CA  1 
ATOM   1902 C C   . HIS B 1 99  ? -28.08126 -9.79746  -13.19796 1.000 14.89809 ? 99  HIS B C   1 
ATOM   1903 O O   . HIS B 1 99  ? -27.63422 -10.84970 -12.72466 1.000 18.02368 ? 99  HIS B O   1 
ATOM   1904 C CB  . HIS B 1 99  ? -27.82257 -8.47779  -11.13579 1.000 17.88140 ? 99  HIS B CB  1 
ATOM   1905 C CG  . HIS B 1 99  ? -27.07550 -7.43235  -10.37033 1.000 22.90046 ? 99  HIS B CG  1 
ATOM   1906 N ND1 . HIS B 1 99  ? -25.70302 -7.32086  -10.39843 1.000 28.87200 ? 99  HIS B ND1 1 
ATOM   1907 C CD2 . HIS B 1 99  ? -27.51412 -6.47334  -9.52190  1.000 27.51683 ? 99  HIS B CD2 1 
ATOM   1908 C CE1 . HIS B 1 99  ? -25.32903 -6.32535  -9.61334  1.000 33.46748 ? 99  HIS B CE1 1 
ATOM   1909 N NE2 . HIS B 1 99  ? -26.41011 -5.78936  -9.07651  1.000 27.18707 ? 99  HIS B NE2 1 
ATOM   1910 N N   . ILE B 1 100 ? -29.02682 -9.77221  -14.13561 1.000 13.18654 ? 100 ILE B N   1 
ATOM   1911 C CA  . ILE B 1 100 ? -29.76151 -10.95924 -14.56778 1.000 13.51996 ? 100 ILE B CA  1 
ATOM   1912 C C   . ILE B 1 100 ? -29.31128 -11.36711 -15.96877 1.000 14.83389 ? 100 ILE B C   1 
ATOM   1913 O O   . ILE B 1 100 ? -29.33029 -10.55647 -16.90890 1.000 14.32389 ? 100 ILE B O   1 
ATOM   1914 C CB  . ILE B 1 100 ? -31.27870 -10.71439 -14.53332 1.000 14.22668 ? 100 ILE B CB  1 
ATOM   1915 C CG1 . ILE B 1 100 ? -31.68327 -10.22704 -13.14132 1.000 13.55976 ? 100 ILE B CG1 1 
ATOM   1916 C CG2 . ILE B 1 100 ? -32.04755 -12.00568 -14.89340 1.000 14.06106 ? 100 ILE B CG2 1 
ATOM   1917 C CD1 . ILE B 1 100 ? -33.16269 -9.96642  -12.99883 1.000 16.77963 ? 100 ILE B CD1 1 
ATOM   1918 N N   . TRP B 1 101 ? -28.92465 -12.63013 -16.10310 1.000 12.20344 ? 101 TRP B N   1 
ATOM   1919 C CA  . TRP B 1 101 ? -28.56102 -13.24752 -17.37059 1.000 12.09735 ? 101 TRP B CA  1 
ATOM   1920 C C   . TRP B 1 101 ? -29.50351 -14.41621 -17.60521 1.000 12.69230 ? 101 TRP B C   1 
ATOM   1921 O O   . TRP B 1 101 ? -29.82067 -15.14061 -16.66507 1.000 12.21921 ? 101 TRP B O   1 
ATOM   1922 C CB  . TRP B 1 101 ? -27.12990 -13.76958 -17.34603 1.000 10.57859 ? 101 TRP B CB  1 
ATOM   1923 C CG  . TRP B 1 101 ? -26.07023 -12.73463 -17.20038 1.000 11.22820 ? 101 TRP B CG  1 
ATOM   1924 C CD1 . TRP B 1 101 ? -26.10831 -11.58294 -16.44893 1.000 15.05326 ? 101 TRP B CD1 1 
ATOM   1925 C CD2 . TRP B 1 101 ? -24.77683 -12.78591 -17.79601 1.000 11.31284 ? 101 TRP B CD2 1 
ATOM   1926 N NE1 . TRP B 1 101 ? -24.90997 -10.89729 -16.57686 1.000 13.58782 ? 101 TRP B NE1 1 
ATOM   1927 C CE2 . TRP B 1 101 ? -24.07613 -11.62670 -17.39244 1.000 13.91699 ? 101 TRP B CE2 1 
ATOM   1928 C CE3 . TRP B 1 101 ? -24.14108 -13.70324 -18.64586 1.000 11.24422 ? 101 TRP B CE3 1 
ATOM   1929 C CZ2 . TRP B 1 101 ? -22.77559 -11.36456 -17.81050 1.000 12.82893 ? 101 TRP B CZ2 1 
ATOM   1930 C CZ3 . TRP B 1 101 ? -22.84445 -13.43005 -19.06304 1.000 10.04469 ? 101 TRP B CZ3 1 
ATOM   1931 C CH2 . TRP B 1 101 ? -22.18028 -12.27665 -18.63844 1.000 12.09899 ? 101 TRP B CH2 1 
ATOM   1932 N N   . VAL B 1 102 ? -29.95772 -14.58958 -18.84667 1.000 12.35698 ? 102 VAL B N   1 
ATOM   1933 C CA  . VAL B 1 102 ? -30.96496 -15.59788 -19.19364 1.000 10.85955 ? 102 VAL B CA  1 
ATOM   1934 C C   . VAL B 1 102 ? -30.58214 -16.18033 -20.54921 1.000 12.23382 ? 102 VAL B C   1 
ATOM   1935 O O   . VAL B 1 102 ? -30.53608 -15.44621 -21.54449 1.000 9.65548  ? 102 VAL B O   1 
ATOM   1936 C CB  . VAL B 1 102 ? -32.39007 -15.00982 -19.27768 1.000 12.27907 ? 102 VAL B CB  1 
ATOM   1937 C CG1 . VAL B 1 102 ? -33.40542 -16.10173 -19.57518 1.000 12.34760 ? 102 VAL B CG1 1 
ATOM   1938 C CG2 . VAL B 1 102 ? -32.78003 -14.24815 -18.01045 1.000 12.90883 ? 102 VAL B CG2 1 
ATOM   1939 N N   . TYR B 1 103 ? -30.29544 -17.48936 -20.59074 1.000 9.06652  ? 103 TYR B N   1 
ATOM   1940 C CA  . TYR B 1 103 ? -30.08371 -18.21941 -21.83795 1.000 10.92681 ? 103 TYR B CA  1 
ATOM   1941 C C   . TYR B 1 103 ? -31.13856 -19.30503 -21.99304 1.000 10.94054 ? 103 TYR B C   1 
ATOM   1942 O O   . TYR B 1 103 ? -31.44921 -20.01132 -21.03498 1.000 11.37980 ? 103 TYR B O   1 
ATOM   1943 C CB  . TYR B 1 103 ? -28.72864 -18.92073 -21.87971 1.000 10.10045 ? 103 TYR B CB  1 
ATOM   1944 C CG  . TYR B 1 103 ? -27.47588 -18.08257 -21.92166 1.000 11.00893 ? 103 TYR B CG  1 
ATOM   1945 C CD1 . TYR B 1 103 ? -27.50459 -16.68598 -21.94969 1.000 12.61152 ? 103 TYR B CD1 1 
ATOM   1946 C CD2 . TYR B 1 103 ? -26.25714 -18.71678 -22.05269 1.000 10.44736 ? 103 TYR B CD2 1 
ATOM   1947 C CE1 . TYR B 1 103 ? -26.31138 -15.95000 -22.04285 1.000 9.80856  ? 103 TYR B CE1 1 
ATOM   1948 C CE2 . TYR B 1 103 ? -25.05653 -17.99839 -22.14879 1.000 10.92926 ? 103 TYR B CE2 1 
ATOM   1949 C CZ  . TYR B 1 103 ? -25.08576 -16.63013 -22.13962 1.000 12.92906 ? 103 TYR B CZ  1 
ATOM   1950 O OH  . TYR B 1 103 ? -23.86915 -15.97110 -22.24413 1.000 13.83024 ? 103 TYR B OH  1 
ATOM   1951 N N   . PHE B 1 104 ? -31.65646 -19.46771 -23.20636 1.000 10.76899 ? 104 PHE B N   1 
ATOM   1952 C CA  . PHE B 1 104 ? -32.60129 -20.54091 -23.51871 1.000 7.75026  ? 104 PHE B CA  1 
ATOM   1953 C C   . PHE B 1 104 ? -31.95983 -21.53627 -24.47054 1.000 12.23172 ? 104 PHE B C   1 
ATOM   1954 O O   . PHE B 1 104 ? -31.45615 -21.14252 -25.52452 1.000 12.38291 ? 104 PHE B O   1 
ATOM   1955 C CB  . PHE B 1 104 ? -33.86628 -19.99884 -24.18915 1.000 8.26006  ? 104 PHE B CB  1 
ATOM   1956 C CG  . PHE B 1 104 ? -34.78361 -19.20267 -23.26933 1.000 12.41889 ? 104 PHE B CG  1 
ATOM   1957 C CD1 . PHE B 1 104 ? -34.65989 -19.26899 -21.88761 1.000 13.82492 ? 104 PHE B CD1 1 
ATOM   1958 C CD2 . PHE B 1 104 ? -35.79301 -18.41462 -23.81388 1.000 12.71097 ? 104 PHE B CD2 1 
ATOM   1959 C CE1 . PHE B 1 104 ? -35.52887 -18.53694 -21.05892 1.000 14.70610 ? 104 PHE B CE1 1 
ATOM   1960 C CE2 . PHE B 1 104 ? -36.66793 -17.69985 -22.99997 1.000 12.60624 ? 104 PHE B CE2 1 
ATOM   1961 C CZ  . PHE B 1 104 ? -36.52733 -17.74158 -21.62885 1.000 13.72717 ? 104 PHE B CZ  1 
ATOM   1962 N N   . GLY B 1 105 ? -32.02612 -22.81646 -24.13073 1.000 9.95795  ? 105 GLY B N   1 
ATOM   1963 C CA  . GLY B 1 105 ? -31.61234 -23.87978 -25.03550 1.000 11.09007 ? 105 GLY B CA  1 
ATOM   1964 C C   . GLY B 1 105 ? -32.81399 -24.73348 -25.37863 1.000 13.44443 ? 105 GLY B C   1 
ATOM   1965 O O   . GLY B 1 105 ? -33.72621 -24.88481 -24.57122 1.000 16.20153 ? 105 GLY B O   1 
ATOM   1966 N N   . GLU B 1 106 ? -32.81518 -25.28698 -26.59160 1.000 12.78317 ? 106 GLU B N   1 
ATOM   1967 C CA  . GLU B 1 106 ? -33.95094 -26.07192 -27.07065 1.000 11.98845 ? 106 GLU B CA  1 
ATOM   1968 C C   . GLU B 1 106 ? -33.48646 -27.43960 -27.54116 1.000 14.41539 ? 106 GLU B C   1 
ATOM   1969 O O   . GLU B 1 106 ? -32.38762 -27.57486 -28.08966 1.000 12.15958 ? 106 GLU B O   1 
ATOM   1970 C CB  . GLU B 1 106 ? -34.66507 -25.37516 -28.24183 1.000 14.81647 ? 106 GLU B CB  1 
ATOM   1971 C CG  . GLU B 1 106 ? -35.06091 -23.94538 -27.95966 1.000 14.57621 ? 106 GLU B CG  1 
ATOM   1972 C CD  . GLU B 1 106 ? -35.19699 -23.15660 -29.22274 1.000 15.51006 ? 106 GLU B CD  1 
ATOM   1973 O OE1 . GLU B 1 106 ? -34.14814 -22.63830 -29.68621 1.000 16.60636 ? 106 GLU B OE1 1 
ATOM   1974 O OE2 . GLU B 1 106 ? -36.32427 -23.04700 -29.74248 1.000 15.83164 ? 106 GLU B OE2 1 
ATOM   1975 N N   . MET B 1 107 ? -34.34349 -28.43849 -27.34575 1.000 11.27108 ? 107 MET B N   1 
ATOM   1976 C CA  . MET B 1 107 ? -34.13917 -29.79180 -27.83937 1.000 13.83170 ? 107 MET B CA  1 
ATOM   1977 C C   . MET B 1 107 ? -35.43816 -30.33960 -28.41759 1.000 13.23167 ? 107 MET B C   1 
ATOM   1978 O O   . MET B 1 107 ? -36.53210 -29.85569 -28.09487 1.000 12.78507 ? 107 MET B O   1 
ATOM   1979 C CB  . MET B 1 107 ? -33.64512 -30.72594 -26.72283 1.000 14.64892 ? 107 MET B CB  1 
ATOM   1980 C CG  . MET B 1 107 ? -32.44931 -30.21929 -25.95911 1.000 14.81329 ? 107 MET B CG  1 
ATOM   1981 S SD  . MET B 1 107 ? -32.58132 -30.53375 -24.16133 1.000 20.81214 ? 107 MET B SD  1 
ATOM   1982 C CE  . MET B 1 107 ? -33.67300 -29.18287 -23.77846 1.000 13.68235 ? 107 MET B CE  1 
ATOM   1983 N N   . PRO B 1 108 ? -35.35248 -31.35093 -29.27985 1.000 12.45065 ? 108 PRO B N   1 
ATOM   1984 C CA  . PRO B 1 108 ? -36.57578 -32.03036 -29.72752 1.000 14.60762 ? 108 PRO B CA  1 
ATOM   1985 C C   . PRO B 1 108 ? -37.32115 -32.62539 -28.54810 1.000 12.79778 ? 108 PRO B C   1 
ATOM   1986 O O   . PRO B 1 108 ? -36.71908 -33.24730 -27.67340 1.000 12.96914 ? 108 PRO B O   1 
ATOM   1987 C CB  . PRO B 1 108 ? -36.05321 -33.12307 -30.67467 1.000 16.88526 ? 108 PRO B CB  1 
ATOM   1988 C CG  . PRO B 1 108 ? -34.71432 -32.62589 -31.12564 1.000 15.05237 ? 108 PRO B CG  1 
ATOM   1989 C CD  . PRO B 1 108 ? -34.14666 -31.86544 -29.95525 1.000 14.57348 ? 108 PRO B CD  1 
ATOM   1990 N N   . ALA B 1 109 ? -38.64889 -32.44815 -28.54317 1.000 12.85303 ? 109 ALA B N   1 
ATOM   1991 C CA  . ALA B 1 109 ? -39.46857 -33.01650 -27.47619 1.000 13.28932 ? 109 ALA B CA  1 
ATOM   1992 C C   . ALA B 1 109 ? -39.28472 -34.53296 -27.38014 1.000 15.35656 ? 109 ALA B C   1 
ATOM   1993 O O   . ALA B 1 109 ? -39.40443 -35.11168 -26.28746 1.000 12.34047 ? 109 ALA B O   1 
ATOM   1994 C CB  . ALA B 1 109 ? -40.94241 -32.67064 -27.71284 1.000 16.16978 ? 109 ALA B CB  1 
ATOM   1995 N N   . GLN B 1 110 ? -38.95433 -35.18234 -28.50309 1.000 12.40428 ? 110 GLN B N   1 
ATOM   1996 C CA  . GLN B 1 110 ? -38.74825 -36.62705 -28.50390 1.000 14.13509 ? 110 GLN B CA  1 
ATOM   1997 C C   . GLN B 1 110 ? -37.54970 -37.07770 -27.67680 1.000 14.06385 ? 110 GLN B C   1 
ATOM   1998 O O   . GLN B 1 110 ? -37.44249 -38.27621 -27.40679 1.000 13.15088 ? 110 GLN B O   1 
ATOM   1999 C CB  . GLN B 1 110 ? -38.60796 -37.17447 -29.93831 1.000 17.62289 ? 110 GLN B CB  1 
ATOM   2000 C CG  . GLN B 1 110 ? -39.62573 -36.66657 -30.96824 1.000 29.19362 ? 110 GLN B CG  1 
ATOM   2001 C CD  . GLN B 1 110 ? -39.20719 -35.40203 -31.72473 1.000 30.32624 ? 110 GLN B CD  1 
ATOM   2002 O OE1 . GLN B 1 110 ? -39.13595 -34.30115 -31.17073 1.000 21.06829 ? 110 GLN B OE1 1 
ATOM   2003 N NE2 . GLN B 1 110 ? -38.90948 -35.57518 -33.01319 1.000 37.73680 ? 110 GLN B NE2 1 
ATOM   2004 N N   . GLN B 1 111 ? -36.66054 -36.17491 -27.26351 1.000 13.32112 ? 111 GLN B N   1 
ATOM   2005 C CA  . GLN B 1 111 ? -35.58021 -36.53764 -26.34371 1.000 11.95364 ? 111 GLN B CA  1 
ATOM   2006 C C   . GLN B 1 111 ? -35.69494 -35.80649 -25.01701 1.000 14.16662 ? 111 GLN B C   1 
ATOM   2007 O O   . GLN B 1 111 ? -34.68933 -35.55890 -24.35097 1.000 12.88017 ? 111 GLN B O   1 
ATOM   2008 C CB  . GLN B 1 111 ? -34.20270 -36.30673 -26.97144 1.000 12.22612 ? 111 GLN B CB  1 
ATOM   2009 C CG  . GLN B 1 111 ? -33.89119 -34.87826 -27.38502 1.000 14.11210 ? 111 GLN B CG  1 
ATOM   2010 C CD  . GLN B 1 111 ? -32.84565 -34.84053 -28.48379 1.000 13.90027 ? 111 GLN B CD  1 
ATOM   2011 O OE1 . GLN B 1 111 ? -33.03852 -35.42825 -29.55471 1.000 14.49405 ? 111 GLN B OE1 1 
ATOM   2012 N NE2 . GLN B 1 111 ? -31.74457 -34.14436 -28.23692 1.000 13.44164 ? 111 GLN B NE2 1 
ATOM   2013 N N   . MET B 1 112 ? -36.91797 -35.46227 -24.60959 1.000 11.67601 ? 112 MET B N   1 
ATOM   2014 C CA  . MET B 1 112 ? -37.15113 -34.93118 -23.27660 1.000 12.70796 ? 112 MET B CA  1 
ATOM   2015 C C   . MET B 1 112 ? -38.27663 -35.64689 -22.54599 1.000 11.60787 ? 112 MET B C   1 
ATOM   2016 O O   . MET B 1 112 ? -39.32802 -35.94217 -23.12064 1.000 12.99948 ? 112 MET B O   1 
ATOM   2017 C CB  . MET B 1 112 ? -37.30795 -33.40100 -23.22176 1.000 15.39233 ? 112 MET B CB  1 
ATOM   2018 C CG  . MET B 1 112 ? -36.53673 -32.55557 -24.21949 1.000 12.80337 ? 112 MET B CG  1 
ATOM   2019 S SD  . MET B 1 112 ? -37.22599 -30.96274 -24.72177 1.000 14.71371 ? 112 MET B SD  1 
ATOM   2020 C CE  . MET B 1 112 ? -37.29601 -30.19964 -23.08163 1.000 14.05636 ? 112 MET B CE  1 
ATOM   2021 N N   . VAL B 1 113 ? -37.98661 -35.97231 -21.28311 1.000 13.88322 ? 113 VAL B N   1 
ATOM   2022 C CA  . VAL B 1 113 ? -38.82119 -36.78663 -20.40625 1.000 10.36932 ? 113 VAL B CA  1 
ATOM   2023 C C   . VAL B 1 113 ? -39.11317 -35.98010 -19.14275 1.000 11.91271 ? 113 VAL B C   1 
ATOM   2024 O O   . VAL B 1 113 ? -38.19056 -35.46948 -18.49804 1.000 11.95786 ? 113 VAL B O   1 
ATOM   2025 C CB  . VAL B 1 113 ? -38.10918 -38.10710 -20.04957 1.000 12.91215 ? 113 VAL B CB  1 
ATOM   2026 C CG1 . VAL B 1 113 ? -38.83857 -38.84329 -18.93839 1.000 13.74705 ? 113 VAL B CG1 1 
ATOM   2027 C CG2 . VAL B 1 113 ? -37.92977 -38.98657 -21.29565 1.000 10.98416 ? 113 VAL B CG2 1 
ATOM   2028 N N   . GLN B 1 114 ? -40.39086 -35.87234 -18.77979 1.000 13.00984 ? 114 GLN B N   1 
ATOM   2029 C CA  . GLN B 1 114 ? -40.77186 -35.28122 -17.50400 1.000 12.73548 ? 114 GLN B CA  1 
ATOM   2030 C C   . GLN B 1 114 ? -41.75665 -36.22744 -16.85037 1.000 11.25547 ? 114 GLN B C   1 
ATOM   2031 O O   . GLN B 1 114 ? -42.59177 -36.82265 -17.54047 1.000 12.36929 ? 114 GLN B O   1 
ATOM   2032 C CB  . GLN B 1 114 ? -41.39355 -33.88786 -17.68218 1.000 12.45474 ? 114 GLN B CB  1 
ATOM   2033 C CG  . GLN B 1 114 ? -40.56960 -32.94025 -18.55649 1.000 12.85005 ? 114 GLN B CG  1 
ATOM   2034 C CD  . GLN B 1 114 ? -41.07458 -31.49585 -18.55416 1.000 13.55436 ? 114 GLN B CD  1 
ATOM   2035 O OE1 . GLN B 1 114 ? -40.41622 -30.60350 -19.07600 1.000 15.78307 ? 114 GLN B OE1 1 
ATOM   2036 N NE2 . GLN B 1 114 ? -42.23532 -31.26177 -17.94843 1.000 15.25287 ? 114 GLN B NE2 1 
ATOM   2037 N N   . TYR B 1 115 ? -41.64554 -36.37490 -15.52625 1.000 12.58948 ? 115 TYR B N   1 
ATOM   2038 C CA  . TYR B 1 115 ? -42.48632 -37.31174 -14.77904 1.000 11.67511 ? 115 TYR B CA  1 
ATOM   2039 C C   . TYR B 1 115 ? -42.40888 -38.71323 -15.38238 1.000 13.11208 ? 115 TYR B C   1 
ATOM   2040 O O   . TYR B 1 115 ? -43.41287 -39.43802 -15.43393 1.000 13.78562 ? 115 TYR B O   1 
ATOM   2041 C CB  . TYR B 1 115 ? -43.94862 -36.84268 -14.73039 1.000 14.25840 ? 115 TYR B CB  1 
ATOM   2042 C CG  . TYR B 1 115 ? -44.19959 -35.51624 -14.01773 1.000 14.17466 ? 115 TYR B CG  1 
ATOM   2043 C CD1 . TYR B 1 115 ? -44.37319 -35.46663 -12.64110 1.000 21.50602 ? 115 TYR B CD1 1 
ATOM   2044 C CD2 . TYR B 1 115 ? -44.31945 -34.32841 -14.73974 1.000 14.21812 ? 115 TYR B CD2 1 
ATOM   2045 C CE1 . TYR B 1 115 ? -44.61257 -34.26681 -11.98974 1.000 15.66666 ? 115 TYR B CE1 1 
ATOM   2046 C CE2 . TYR B 1 115 ? -44.55795 -33.12327 -14.09951 1.000 18.61041 ? 115 TYR B CE2 1 
ATOM   2047 C CZ  . TYR B 1 115 ? -44.71183 -33.10346 -12.72138 1.000 16.69057 ? 115 TYR B CZ  1 
ATOM   2048 O OH  . TYR B 1 115 ? -44.95658 -31.91195 -12.06815 1.000 20.80965 ? 115 TYR B OH  1 
ATOM   2049 N N   . GLY B 1 116 ? -41.22874 -39.07516 -15.90208 1.000 14.39283 ? 116 GLY B N   1 
ATOM   2050 C CA  . GLY B 1 116 ? -41.03077 -40.37042 -16.52652 1.000 15.81679 ? 116 GLY B CA  1 
ATOM   2051 C C   . GLY B 1 116 ? -41.71705 -40.58823 -17.85690 1.000 16.99118 ? 116 GLY B C   1 
ATOM   2052 O O   . GLY B 1 116 ? -41.73868 -41.73059 -18.34245 1.000 18.23465 ? 116 GLY B O   1 
ATOM   2053 N N   . ARG B 1 117 ? -42.26768 -39.54073 -18.47409 1.000 16.13091 ? 117 ARG B N   1 
ATOM   2054 C CA  . ARG B 1 117 ? -42.95521 -39.63994 -19.75777 1.000 15.09372 ? 117 ARG B CA  1 
ATOM   2055 C C   . ARG B 1 117 ? -42.34556 -38.69569 -20.78653 1.000 12.27812 ? 117 ARG B C   1 
ATOM   2056 O O   . ARG B 1 117 ? -41.94246 -37.57193 -20.46033 1.000 13.01770 ? 117 ARG B O   1 
ATOM   2057 C CB  . ARG B 1 117 ? -44.44956 -39.32909 -19.62089 1.000 16.20007 ? 117 ARG B CB  1 
ATOM   2058 C CG  . ARG B 1 117 ? -45.06482 -40.07508 -18.47289 1.000 20.02991 ? 117 ARG B CG  1 
ATOM   2059 C CD  . ARG B 1 117 ? -45.32206 -41.53698 -18.78700 1.000 25.74506 ? 117 ARG B CD  1 
ATOM   2060 N NE  . ARG B 1 117 ? -45.75686 -41.78375 -20.15375 1.000 24.32118 ? 117 ARG B NE  1 
ATOM   2061 C CZ  . ARG B 1 117 ? -46.99784 -42.13133 -20.46226 1.000 31.60831 ? 117 ARG B CZ  1 
ATOM   2062 N NH1 . ARG B 1 117 ? -47.93834 -42.21645 -19.53449 1.000 26.36858 ? 117 ARG B NH1 1 
ATOM   2063 N NH2 . ARG B 1 117 ? -47.30531 -42.39897 -21.72735 1.000 32.67826 ? 117 ARG B NH2 1 
ATOM   2064 N N   . PHE B 1 118 ? -42.31898 -39.14034 -22.04105 1.000 15.79090 ? 118 PHE B N   1 
ATOM   2065 C CA  . PHE B 1 118 ? -41.81487 -38.27527 -23.10452 1.000 15.53610 ? 118 PHE B CA  1 
ATOM   2066 C C   . PHE B 1 118 ? -42.79396 -37.13594 -23.34022 1.000 16.73535 ? 118 PHE B C   1 
ATOM   2067 O O   . PHE B 1 118 ? -44.01461 -37.33398 -23.31997 1.000 14.04422 ? 118 PHE B O   1 
ATOM   2068 C CB  . PHE B 1 118 ? -41.59712 -39.07049 -24.39023 1.000 13.65814 ? 118 PHE B CB  1 
ATOM   2069 C CG  . PHE B 1 118 ? -40.35703 -39.93385 -24.34947 1.000 13.87229 ? 118 PHE B CG  1 
ATOM   2070 C CD1 . PHE B 1 118 ? -39.13067 -39.42348 -24.71554 1.000 13.99180 ? 118 PHE B CD1 1 
ATOM   2071 C CD2 . PHE B 1 118 ? -40.42814 -41.23704 -23.87952 1.000 17.70491 ? 118 PHE B CD2 1 
ATOM   2072 C CE1 . PHE B 1 118 ? -37.98150 -40.20869 -24.65357 1.000 15.52158 ? 118 PHE B CE1 1 
ATOM   2073 C CE2 . PHE B 1 118 ? -39.28466 -42.03861 -23.81005 1.000 19.49876 ? 118 PHE B CE2 1 
ATOM   2074 C CZ  . PHE B 1 118 ? -38.06057 -41.51777 -24.19213 1.000 19.33553 ? 118 PHE B CZ  1 
ATOM   2075 N N   . LEU B 1 119 ? -42.25115 -35.93600 -23.54564 1.000 13.29139 ? 119 LEU B N   1 
ATOM   2076 C CA  . LEU B 1 119 ? -43.07398 -34.74999 -23.77764 1.000 12.66044 ? 119 LEU B CA  1 
ATOM   2077 C C   . LEU B 1 119 ? -43.72240 -34.76192 -25.15721 1.000 16.94800 ? 119 LEU B C   1 
ATOM   2078 O O   . LEU B 1 119 ? -43.18006 -35.33642 -26.10397 1.000 15.34485 ? 119 LEU B O   1 
ATOM   2079 C CB  . LEU B 1 119 ? -42.23393 -33.48014 -23.64158 1.000 10.97952 ? 119 LEU B CB  1 
ATOM   2080 C CG  . LEU B 1 119 ? -41.62558 -33.20178 -22.27450 1.000 12.95822 ? 119 LEU B CG  1 
ATOM   2081 C CD1 . LEU B 1 119 ? -40.91890 -31.85562 -22.26300 1.000 13.05708 ? 119 LEU B CD1 1 
ATOM   2082 C CD2 . LEU B 1 119 ? -42.80111 -33.15506 -21.29105 1.000 18.61383 ? 119 LEU B CD2 1 
ATOM   2083 N N   . PRO B 1 120 ? -44.85918 -34.07069 -25.30754 1.000 16.33708 ? 120 PRO B N   1 
ATOM   2084 C CA  . PRO B 1 120 ? -45.41437 -33.83464 -26.64256 1.000 16.96402 ? 120 PRO B CA  1 
ATOM   2085 C C   . PRO B 1 120 ? -44.80807 -32.61352 -27.31633 1.000 19.40538 ? 120 PRO B C   1 
ATOM   2086 O O   . PRO B 1 120 ? -44.04352 -31.88305 -26.68926 1.000 21.63261 ? 120 PRO B O   1 
ATOM   2087 C CB  . PRO B 1 120 ? -46.89926 -33.61353 -26.34695 1.000 18.23250 ? 120 PRO B CB  1 
ATOM   2088 C CG  . PRO B 1 120 ? -46.87987 -32.87587 -25.00291 1.000 18.19235 ? 120 PRO B CG  1 
ATOM   2089 C CD  . PRO B 1 120 ? -45.60472 -33.33119 -24.26636 1.000 16.64850 ? 120 PRO B CD  1 
ATOM   2090 N N   . GLN B 1 121 ? -45.15936 -32.36506 -28.57400 1.000 28.42567 ? 121 GLN B N   1 
ATOM   2091 C CA  . GLN B 1 121 ? -44.79633 -31.10554 -29.22012 1.000 23.60721 ? 121 GLN B CA  1 
ATOM   2092 C C   . GLN B 1 121 ? -45.46116 -29.91036 -28.53498 1.000 27.47828 ? 121 GLN B C   1 
ATOM   2093 O O   . GLN B 1 121 ? -46.54016 -30.04167 -27.94631 1.000 24.55685 ? 121 GLN B O   1 
ATOM   2094 C CB  . GLN B 1 121 ? -45.18767 -31.13837 -30.68841 1.000 30.67927 ? 121 GLN B CB  1 
ATOM   2095 C CG  . GLN B 1 121 ? -44.46258 -32.19598 -31.51670 1.000 29.75609 ? 121 GLN B CG  1 
ATOM   2096 C CD  . GLN B 1 121 ? -42.95016 -32.18293 -31.29644 1.000 38.66568 ? 121 GLN B CD  1 
ATOM   2097 O OE1 . GLN B 1 121 ? -42.30126 -33.23315 -31.23671 1.000 34.47958 ? 121 GLN B OE1 1 
ATOM   2098 N NE2 . GLN B 1 121 ? -42.37652 -30.97411 -31.20997 1.000 28.83638 ? 121 GLN B NE2 1 
ATOM   2099 N N   . PRO B 1 122 ? -44.82600 -28.73525 -28.59332 1.000 30.97241 ? 122 PRO B N   1 
ATOM   2100 C CA  . PRO B 1 122 ? -45.39702 -27.54150 -27.95484 1.000 29.92336 ? 122 PRO B CA  1 
ATOM   2101 C C   . PRO B 1 122 ? -46.79961 -27.25803 -28.46679 1.000 34.21240 ? 122 PRO B C   1 
ATOM   2102 O O   . PRO B 1 122 ? -47.05401 -27.27602 -29.67341 1.000 28.80259 ? 122 PRO B O   1 
ATOM   2103 C CB  . PRO B 1 122 ? -44.42187 -26.43357 -28.36265 1.000 33.12470 ? 122 PRO B CB  1 
ATOM   2104 C CG  . PRO B 1 122 ? -43.10027 -27.12496 -28.39332 1.000 26.60880 ? 122 PRO B CG  1 
ATOM   2105 C CD  . PRO B 1 122 ? -43.40053 -28.54047 -28.91975 1.000 25.71695 ? 122 PRO B CD  1 
ATOM   2106 N N   . GLY B 1 123 ? -47.71350 -27.00507 -27.53386 1.000 28.11906 ? 123 GLY B N   1 
ATOM   2107 C CA  . GLY B 1 123 ? -49.08992 -26.73105 -27.87850 1.000 33.55080 ? 123 GLY B CA  1 
ATOM   2108 C C   . GLY B 1 123 ? -49.98650 -27.94626 -27.90166 1.000 26.59003 ? 123 GLY B C   1 
ATOM   2109 O O   . GLY B 1 123 ? -51.19336 -27.80318 -28.14101 1.000 31.83358 ? 123 GLY B O   1 
ATOM   2110 N N   . HIS B 1 124 ? -49.43944 -29.13710 -27.67541 1.000 26.42844 ? 124 HIS B N   1 
ATOM   2111 C CA  . HIS B 1 124 ? -50.20943 -30.37453 -27.65824 1.000 25.99246 ? 124 HIS B CA  1 
ATOM   2112 C C   . HIS B 1 124 ? -50.27029 -30.97615 -26.26575 1.000 23.59499 ? 124 HIS B C   1 
ATOM   2113 O O   . HIS B 1 124 ? -50.45749 -32.18651 -26.11777 1.000 28.52054 ? 124 HIS B O   1 
ATOM   2114 C CB  . HIS B 1 124 ? -49.63682 -31.38886 -28.64736 1.000 26.91826 ? 124 HIS B CB  1 
ATOM   2115 C CG  . HIS B 1 124 ? -49.71556 -30.94564 -30.07116 1.000 35.66083 ? 124 HIS B CG  1 
ATOM   2116 N ND1 . HIS B 1 124 ? -49.30496 -29.69768 -30.48714 1.000 40.19601 ? 124 HIS B ND1 1 
ATOM   2117 C CD2 . HIS B 1 124 ? -50.14722 -31.59039 -31.18079 1.000 37.60084 ? 124 HIS B CD2 1 
ATOM   2118 C CE1 . HIS B 1 124 ? -49.49138 -29.58760 -31.79022 1.000 42.91099 ? 124 HIS B CE1 1 
ATOM   2119 N NE2 . HIS B 1 124 ? -50.00124 -30.72234 -32.23513 1.000 48.92353 ? 124 HIS B NE2 1 
ATOM   2120 N N   . GLU B 1 125 ? -50.12885 -30.12740 -25.24206 1.000 22.96153 ? 125 GLU B N   1 
ATOM   2121 C CA  . GLU B 1 125 ? -50.08496 -30.59810 -23.86283 1.000 25.13958 ? 125 GLU B CA  1 
ATOM   2122 C C   . GLU B 1 125 ? -51.43765 -31.11056 -23.38473 1.000 26.97458 ? 125 GLU B C   1 
ATOM   2123 O O   . GLU B 1 125 ? -51.48640 -32.05304 -22.59233 1.000 25.90459 ? 125 GLU B O   1 
ATOM   2124 C CB  . GLU B 1 125 ? -49.58448 -29.48345 -22.94321 1.000 26.63338 ? 125 GLU B CB  1 
ATOM   2125 C CG  . GLU B 1 125 ? -48.14467 -29.07531 -23.22330 1.000 27.34794 ? 125 GLU B CG  1 
ATOM   2126 C CD  . GLU B 1 125 ? -48.02972 -28.00153 -24.29351 1.000 29.50207 ? 125 GLU B CD  1 
ATOM   2127 O OE1 . GLU B 1 125 ? -49.08247 -27.48870 -24.74190 1.000 31.26545 ? 125 GLU B OE1 1 
ATOM   2128 O OE2 . GLU B 1 125 ? -46.88567 -27.69471 -24.70099 1.000 27.95269 ? 125 GLU B OE2 1 
ATOM   2129 N N   . GLY B 1 126 ? -52.53880 -30.50531 -23.83305 1.000 29.94738 ? 126 GLY B N   1 
ATOM   2130 C CA  . GLY B 1 126 ? -53.84913 -30.99016 -23.41362 1.000 28.88305 ? 126 GLY B CA  1 
ATOM   2131 C C   . GLY B 1 126 ? -54.11025 -32.41668 -23.86312 1.000 25.23947 ? 126 GLY B C   1 
ATOM   2132 O O   . GLY B 1 126 ? -54.46826 -33.28230 -23.05809 1.000 30.75365 ? 126 GLY B O   1 
ATOM   2133 N N   . GLU B 1 127 ? -53.93491 -32.67189 -25.16068 1.000 23.42136 ? 127 GLU B N   1 
ATOM   2134 C CA  . GLU B 1 127 ? -54.09708 -34.00822 -25.73027 1.000 25.81990 ? 127 GLU B CA  1 
ATOM   2135 C C   . GLU B 1 127 ? -53.20753 -35.02980 -25.03644 1.000 29.58251 ? 127 GLU B C   1 
ATOM   2136 O O   . GLU B 1 127 ? -53.63469 -36.14908 -24.72316 1.000 25.05124 ? 127 GLU B O   1 
ATOM   2137 C CB  . GLU B 1 127 ? -53.75324 -33.93956 -27.21087 1.000 36.78320 ? 127 GLU B CB  1 
ATOM   2138 C CG  . GLU B 1 127 ? -53.75433 -35.25169 -27.94308 1.000 40.73731 ? 127 GLU B CG  1 
ATOM   2139 C CD  . GLU B 1 127 ? -53.94270 -35.04949 -29.42919 1.000 51.77471 ? 127 GLU B CD  1 
ATOM   2140 O OE1 . GLU B 1 127 ? -54.72060 -34.14772 -29.81199 1.000 55.01012 ? 127 GLU B OE1 1 
ATOM   2141 O OE2 . GLU B 1 127 ? -53.28315 -35.76691 -30.21177 1.000 55.70728 ? 127 GLU B OE2 1 
ATOM   2142 N N   . TRP B 1 128 ? -51.94664 -34.66295 -24.82443 1.000 25.61909 ? 128 TRP B N   1 
ATOM   2143 C CA  . TRP B 1 128 ? -50.99452 -35.53568 -24.15140 1.000 20.72569 ? 128 TRP B CA  1 
ATOM   2144 C C   . TRP B 1 128 ? -51.41706 -35.79285 -22.71282 1.000 24.91124 ? 128 TRP B C   1 
ATOM   2145 O O   . TRP B 1 128 ? -51.37896 -36.93571 -22.23880 1.000 21.22761 ? 128 TRP B O   1 
ATOM   2146 C CB  . TRP B 1 128 ? -49.62196 -34.86912 -24.22632 1.000 24.12009 ? 128 TRP B CB  1 
ATOM   2147 C CG  . TRP B 1 128 ? -48.49223 -35.40849 -23.40038 1.000 20.32894 ? 128 TRP B CG  1 
ATOM   2148 C CD1 . TRP B 1 128 ? -47.55027 -36.29861 -23.81687 1.000 20.26644 ? 128 TRP B CD1 1 
ATOM   2149 C CD2 . TRP B 1 128 ? -48.13239 -35.04533 -22.05443 1.000 15.84976 ? 128 TRP B CD2 1 
ATOM   2150 N NE1 . TRP B 1 128 ? -46.64215 -36.53266 -22.81876 1.000 20.31354 ? 128 TRP B NE1 1 
ATOM   2151 C CE2 . TRP B 1 128 ? -46.97420 -35.77792 -21.72478 1.000 17.06542 ? 128 TRP B CE2 1 
ATOM   2152 C CE3 . TRP B 1 128 ? -48.68024 -34.18670 -21.09514 1.000 15.62286 ? 128 TRP B CE3 1 
ATOM   2153 C CZ2 . TRP B 1 128 ? -46.35574 -35.68194 -20.48168 1.000 22.47989 ? 128 TRP B CZ2 1 
ATOM   2154 C CZ3 . TRP B 1 128 ? -48.05901 -34.08918 -19.85922 1.000 20.72331 ? 128 TRP B CZ3 1 
ATOM   2155 C CH2 . TRP B 1 128 ? -46.90951 -34.82650 -19.56362 1.000 22.63371 ? 128 TRP B CH2 1 
ATOM   2156 N N   . PHE B 1 129 ? -51.83580 -34.73785 -22.00507 1.000 20.57650 ? 129 PHE B N   1 
ATOM   2157 C CA  . PHE B 1 129 ? -52.24410 -34.88359 -20.61528 1.000 24.05383 ? 129 PHE B CA  1 
ATOM   2158 C C   . PHE B 1 129 ? -53.46559 -35.77804 -20.48388 1.000 21.08994 ? 129 PHE B C   1 
ATOM   2159 O O   . PHE B 1 129 ? -53.57252 -36.53562 -19.51115 1.000 22.03795 ? 129 PHE B O   1 
ATOM   2160 C CB  . PHE B 1 129 ? -52.50396 -33.50223 -20.00785 1.000 24.63501 ? 129 PHE B CB  1 
ATOM   2161 C CG  . PHE B 1 129 ? -52.82690 -33.52487 -18.54473 1.000 26.14340 ? 129 PHE B CG  1 
ATOM   2162 C CD1 . PHE B 1 129 ? -51.84408 -33.78091 -17.60489 1.000 20.69999 ? 129 PHE B CD1 1 
ATOM   2163 C CD2 . PHE B 1 129 ? -54.10653 -33.23735 -18.10757 1.000 27.55687 ? 129 PHE B CD2 1 
ATOM   2164 C CE1 . PHE B 1 129 ? -52.13914 -33.79084 -16.25118 1.000 25.08160 ? 129 PHE B CE1 1 
ATOM   2165 C CE2 . PHE B 1 129 ? -54.39960 -33.23186 -16.76506 1.000 22.39180 ? 129 PHE B CE2 1 
ATOM   2166 C CZ  . PHE B 1 129 ? -53.40522 -33.50781 -15.83728 1.000 26.56070 ? 129 PHE B CZ  1 
ATOM   2167 N N   . ASP B 1 130 ? -54.37426 -35.73729 -21.45974 1.000 26.07800 ? 130 ASP B N   1 
ATOM   2168 C CA  . ASP B 1 130 ? -55.55805 -36.58499 -21.37314 1.000 27.05710 ? 130 ASP B CA  1 
ATOM   2169 C C   . ASP B 1 130 ? -55.27485 -38.04858 -21.68539 1.000 29.37821 ? 130 ASP B C   1 
ATOM   2170 O O   . ASP B 1 130 ? -56.10648 -38.90200 -21.35994 1.000 34.74999 ? 130 ASP B O   1 
ATOM   2171 C CB  . ASP B 1 130 ? -56.67442 -36.08810 -22.29153 1.000 29.55505 ? 130 ASP B CB  1 
ATOM   2172 C CG  . ASP B 1 130 ? -57.19399 -34.71878 -21.89665 1.000 33.80577 ? 130 ASP B CG  1 
ATOM   2173 O OD1 . ASP B 1 130 ? -57.17452 -34.39025 -20.69190 1.000 36.74425 ? 130 ASP B OD1 1 
ATOM   2174 O OD2 . ASP B 1 130 ? -57.67866 -33.98915 -22.78730 1.000 38.72389 ? 130 ASP B OD2 1 
ATOM   2175 N N   . ASN B 1 131 ? -54.14082 -38.38677 -22.29577 1.000 22.39073 ? 131 ASN B N   1 
ATOM   2176 C CA  . ASN B 1 131 ? -53.86454 -39.79968 -22.49628 1.000 25.44214 ? 131 ASN B CA  1 
ATOM   2177 C C   . ASN B 1 131 ? -52.92386 -40.33206 -21.41518 1.000 23.66686 ? 131 ASN B C   1 
ATOM   2178 O O   . ASN B 1 131 ? -52.33169 -41.40044 -21.57865 1.000 21.44915 ? 131 ASN B O   1 
ATOM   2179 C CB  . ASN B 1 131 ? -53.32069 -40.05617 -23.90595 1.000 30.59754 ? 131 ASN B CB  1 
ATOM   2180 C CG  . ASN B 1 131 ? -53.36840 -41.54745 -24.29789 1.000 40.26756 ? 131 ASN B CG  1 
ATOM   2181 O OD1 . ASN B 1 131 ? -54.23550 -42.31688 -23.82053 1.000 34.16827 ? 131 ASN B OD1 1 
ATOM   2182 N ND2 . ASN B 1 131 ? -52.44780 -41.95901 -25.16944 1.000 36.46203 ? 131 ASN B ND2 1 
ATOM   2183 N N   . LEU B 1 132 ? -52.76584 -39.59168 -20.31718 1.000 17.97419 ? 132 LEU B N   1 
ATOM   2184 C CA  . LEU B 1 132 ? -52.02146 -40.07239 -19.16132 1.000 17.61342 ? 132 LEU B CA  1 
ATOM   2185 C C   . LEU B 1 132 ? -52.95169 -40.86209 -18.25004 1.000 15.15883 ? 132 LEU B C   1 
ATOM   2186 O O   . LEU B 1 132 ? -54.16131 -40.63407 -18.22625 1.000 21.36580 ? 132 LEU B O   1 
ATOM   2187 C CB  . LEU B 1 132 ? -51.40958 -38.91176 -18.37308 1.000 17.71585 ? 132 LEU B CB  1 
ATOM   2188 C CG  . LEU B 1 132 ? -50.32621 -38.09644 -19.07458 1.000 18.79190 ? 132 LEU B CG  1 
ATOM   2189 C CD1 . LEU B 1 132 ? -50.07065 -36.76917 -18.33912 1.000 22.92139 ? 132 LEU B CD1 1 
ATOM   2190 C CD2 . LEU B 1 132 ? -49.05509 -38.91769 -19.20615 1.000 23.48601 ? 132 LEU B CD2 1 
ATOM   2191 N N   . SER B 1 133 ? -52.37948 -41.79059 -17.49396 1.000 15.59753 ? 133 SER B N   1 
ATOM   2192 C CA  . SER B 1 133 ? -53.19050 -42.53498 -16.54587 1.000 18.49194 ? 133 SER B CA  1 
ATOM   2193 C C   . SER B 1 133 ? -53.69142 -41.62423 -15.42762 1.000 18.92443 ? 133 SER B C   1 
ATOM   2194 O O   . SER B 1 133 ? -53.14667 -40.55115 -15.16321 1.000 18.78217 ? 133 SER B O   1 
ATOM   2195 C CB  . SER B 1 133 ? -52.39505 -43.69241 -15.94487 1.000 18.06961 ? 133 SER B CB  1 
ATOM   2196 O OG  . SER B 1 133 ? -51.42147 -43.19702 -15.04032 1.000 21.67945 ? 133 SER B OG  1 
ATOM   2197 N N   . SER B 1 134 ? -54.74127 -42.09510 -14.75359 1.000 21.15324 ? 134 SER B N   1 
ATOM   2198 C CA  . SER B 1 134 ? -55.37582 -41.34577 -13.67289 1.000 22.02936 ? 134 SER B CA  1 
ATOM   2199 C C   . SER B 1 134 ? -54.36991 -40.96464 -12.59685 1.000 18.40078 ? 134 SER B C   1 
ATOM   2200 O O   . SER B 1 134 ? -54.31628 -39.81044 -12.14591 1.000 22.02145 ? 134 SER B O   1 
ATOM   2201 C CB  . SER B 1 134 ? -56.48495 -42.20780 -13.06655 1.000 22.88300 ? 134 SER B CB  1 
ATOM   2202 O OG  . SER B 1 134 ? -57.62934 -42.17909 -13.87966 1.000 29.66002 ? 134 SER B OG  1 
ATOM   2203 N N   . ASP B 1 135 ? -53.56394 -41.94104 -12.17333 1.000 19.71355 ? 135 ASP B N   1 
ATOM   2204 C CA  . ASP B 1 135 ? -52.58829 -41.73076 -11.11102 1.000 23.97898 ? 135 ASP B CA  1 
ATOM   2205 C C   . ASP B 1 135 ? -51.54274 -40.70023 -11.51063 1.000 24.17056 ? 135 ASP B C   1 
ATOM   2206 O O   . ASP B 1 135 ? -51.05954 -39.93523 -10.66526 1.000 21.84385 ? 135 ASP B O   1 
ATOM   2207 C CB  . ASP B 1 135 ? -51.89823 -43.05086 -10.77430 1.000 22.51768 ? 135 ASP B CB  1 
ATOM   2208 C CG  . ASP B 1 135 ? -52.75947 -43.96296 -9.92454  1.000 33.59702 ? 135 ASP B CG  1 
ATOM   2209 O OD1 . ASP B 1 135 ? -53.74515 -43.47593 -9.33195  1.000 31.23656 ? 135 ASP B OD1 1 
ATOM   2210 O OD2 . ASP B 1 135 ? -52.44657 -45.17237 -9.86578  1.000 34.00489 ? 135 ASP B OD2 1 
ATOM   2211 N N   . GLU B 1 136 ? -51.14925 -40.69294 -12.78599 1.000 17.55246 ? 136 GLU B N   1 
ATOM   2212 C CA  . GLU B 1 136 ? -50.13473 -39.73690 -13.22161 1.000 21.63197 ? 136 GLU B CA  1 
ATOM   2213 C C   . GLU B 1 136 ? -50.71876 -38.33510 -13.29779 1.000 16.10830 ? 136 GLU B C   1 
ATOM   2214 O O   . GLU B 1 136 ? -50.07518 -37.36278 -12.88269 1.000 19.31902 ? 136 GLU B O   1 
ATOM   2215 C CB  . GLU B 1 136 ? -49.56679 -40.13913 -14.58035 1.000 20.07424 ? 136 GLU B CB  1 
ATOM   2216 C CG  . GLU B 1 136 ? -48.98651 -41.50989 -14.59535 1.000 22.30835 ? 136 GLU B CG  1 
ATOM   2217 C CD  . GLU B 1 136 ? -48.46094 -41.92945 -15.96234 1.000 30.66951 ? 136 GLU B CD  1 
ATOM   2218 O OE1 . GLU B 1 136 ? -47.52490 -41.29974 -16.50133 1.000 25.88719 ? 136 GLU B OE1 1 
ATOM   2219 O OE2 . GLU B 1 136 ? -49.10055 -42.81294 -16.56260 1.000 30.35642 ? 136 GLU B OE2 1 
ATOM   2220 N N   . ARG B 1 137 ? -51.93124 -38.22368 -13.84373 1.000 15.29075 ? 137 ARG B N   1 
ATOM   2221 C CA  . ARG B 1 137 ? -52.69342 -36.97789 -13.83748 1.000 20.35460 ? 137 ARG B CA  1 
ATOM   2222 C C   . ARG B 1 137 ? -52.78793 -36.40272 -12.42722 1.000 21.47537 ? 137 ARG B C   1 
ATOM   2223 O O   . ARG B 1 137 ? -52.49107 -35.22211 -12.19404 1.000 21.28393 ? 137 ARG B O   1 
ATOM   2224 C CB  . ARG B 1 137 ? -54.08417 -37.28093 -14.40795 1.000 24.79665 ? 137 ARG B CB  1 
ATOM   2225 C CG  . ARG B 1 137 ? -54.98410 -36.13951 -14.79621 1.000 37.31125 ? 137 ARG B CG  1 
ATOM   2226 C CD  . ARG B 1 137 ? -55.54950 -36.29845 -16.23122 1.000 35.10163 ? 137 ARG B CD  1 
ATOM   2227 N NE  . ARG B 1 137 ? -55.69452 -37.67677 -16.69093 1.000 30.43679 ? 137 ARG B NE  1 
ATOM   2228 C CZ  . ARG B 1 137 ? -56.59929 -38.53586 -16.23718 1.000 36.54194 ? 137 ARG B CZ  1 
ATOM   2229 N NH1 . ARG B 1 137 ? -57.47724 -38.19248 -15.30754 1.000 43.25038 ? 137 ARG B NH1 1 
ATOM   2230 N NH2 . ARG B 1 137 ? -56.62819 -39.77137 -16.73430 1.000 34.71407 ? 137 ARG B NH2 1 
ATOM   2231 N N   . ALA B 1 138 ? -53.18520 -37.24057 -11.46643 1.000 21.07991 ? 138 ALA B N   1 
ATOM   2232 C CA  . ALA B 1 138 ? -53.33721 -36.79430 -10.07996 1.000 19.21100 ? 138 ALA B CA  1 
ATOM   2233 C C   . ALA B 1 138 ? -52.01758 -36.28326 -9.51598  1.000 23.43235 ? 138 ALA B C   1 
ATOM   2234 O O   . ALA B 1 138 ? -51.96986 -35.22722 -8.87339  1.000 24.80783 ? 138 ALA B O   1 
ATOM   2235 C CB  . ALA B 1 138 ? -53.87686 -37.94214 -9.21665  1.000 20.98061 ? 138 ALA B CB  1 
ATOM   2236 N N   . PHE B 1 139 ? -50.93405 -37.03196 -9.73634  1.000 22.28169 ? 139 PHE B N   1 
ATOM   2237 C CA  . PHE B 1 139 ? -49.63860 -36.63163 -9.21117  1.000 25.70870 ? 139 PHE B CA  1 
ATOM   2238 C C   . PHE B 1 139 ? -49.21902 -35.27432 -9.76610  1.000 25.45760 ? 139 PHE B C   1 
ATOM   2239 O O   . PHE B 1 139 ? -48.75992 -34.40191 -9.01889  1.000 24.94724 ? 139 PHE B O   1 
ATOM   2240 C CB  . PHE B 1 139 ? -48.60056 -37.70457 -9.53423  1.000 21.91310 ? 139 PHE B CB  1 
ATOM   2241 C CG  . PHE B 1 139 ? -47.25127 -37.42614 -8.95836  1.000 27.44578 ? 139 PHE B CG  1 
ATOM   2242 C CD1 . PHE B 1 139 ? -47.01362 -37.59378 -7.60599  1.000 27.51829 ? 139 PHE B CD1 1 
ATOM   2243 C CD2 . PHE B 1 139 ? -46.21738 -36.98986 -9.76958  1.000 25.54782 ? 139 PHE B CD2 1 
ATOM   2244 C CE1 . PHE B 1 139 ? -45.76339 -37.34250 -7.06714  1.000 29.83966 ? 139 PHE B CE1 1 
ATOM   2245 C CE2 . PHE B 1 139 ? -44.96699 -36.72661 -9.23915  1.000 24.35470 ? 139 PHE B CE2 1 
ATOM   2246 C CZ  . PHE B 1 139 ? -44.73784 -36.90766 -7.89048  1.000 31.66535 ? 139 PHE B CZ  1 
ATOM   2247 N N   . MET B 1 140 ? -49.37696 -35.07563 -11.07990 1.000 20.44630 ? 140 MET B N   1 
ATOM   2248 C CA  . MET B 1 140 ? -48.99292 -33.80334 -11.68162 1.000 21.94586 ? 140 MET B CA  1 
ATOM   2249 C C   . MET B 1 140 ? -49.84240 -32.66832 -11.12659 1.000 26.81674 ? 140 MET B C   1 
ATOM   2250 O O   . MET B 1 140 ? -49.34031 -31.57069 -10.86671 1.000 22.68820 ? 140 MET B O   1 
ATOM   2251 C CB  . MET B 1 140 ? -49.14975 -33.86350 -13.19823 1.000 23.20264 ? 140 MET B CB  1 
ATOM   2252 C CG  . MET B 1 140 ? -48.42692 -34.98956 -13.86548 1.000 25.99280 ? 140 MET B CG  1 
ATOM   2253 S SD  . MET B 1 140 ? -48.43956 -34.84261 -15.66026 1.000 24.20727 ? 140 MET B SD  1 
ATOM   2254 C CE  . MET B 1 140 ? -47.11773 -35.98166 -16.05160 1.000 22.31106 ? 140 MET B CE  1 
ATOM   2255 N N   . GLU B 1 141 ? -51.12913 -32.92550 -10.91091 1.000 24.17716 ? 141 GLU B N   1 
ATOM   2256 C CA  . GLU B 1 141 ? -52.04381 -31.87347 -10.48781 1.000 26.10761 ? 141 GLU B CA  1 
ATOM   2257 C C   . GLU B 1 141 ? -51.72468 -31.35583 -9.09317  1.000 24.49533 ? 141 GLU B C   1 
ATOM   2258 O O   . GLU B 1 141 ? -52.14044 -30.23985 -8.75196  1.000 27.17341 ? 141 GLU B O   1 
ATOM   2259 C CB  . GLU B 1 141 ? -53.48508 -32.39257 -10.54359 1.000 27.02482 ? 141 GLU B CB  1 
ATOM   2260 C CG  . GLU B 1 141 ? -54.21231 -32.09730 -11.85452 1.000 30.17148 ? 141 GLU B CG  1 
ATOM   2261 C CD  . GLU B 1 141 ? -55.33880 -33.09795 -12.13841 1.000 35.89384 ? 141 GLU B CD  1 
ATOM   2262 O OE1 . GLU B 1 141 ? -55.66069 -33.92421 -11.24978 1.000 38.54639 ? 141 GLU B OE1 1 
ATOM   2263 O OE2 . GLU B 1 141 ? -55.90627 -33.05311 -13.24954 1.000 43.13942 ? 141 GLU B OE2 1 
ATOM   2264 N N   . THR B 1 142 ? -51.00232 -32.13272 -8.27580  1.000 25.42077 ? 142 THR B N   1 
ATOM   2265 C CA  . THR B 1 142 ? -50.58578 -31.63863 -6.96706  1.000 27.77957 ? 142 THR B CA  1 
ATOM   2266 C C   . THR B 1 142 ? -49.48594 -30.58737 -7.07393  1.000 32.84868 ? 142 THR B C   1 
ATOM   2267 O O   . THR B 1 142 ? -49.27830 -29.82956 -6.11647  1.000 26.68014 ? 142 THR B O   1 
ATOM   2268 C CB  . THR B 1 142 ? -50.11699 -32.79592 -6.07145  1.000 26.63306 ? 142 THR B CB  1 
ATOM   2269 O OG1 . THR B 1 142 ? -48.88050 -33.33259 -6.55996  1.000 28.10432 ? 142 THR B OG1 1 
ATOM   2270 C CG2 . THR B 1 142 ? -51.15646 -33.90063 -6.03811  1.000 28.83932 ? 142 THR B CG2 1 
ATOM   2271 N N   . ASN B 1 143 ? -48.79737 -30.51601 -8.21492  1.000 21.19080 ? 143 ASN B N   1 
ATOM   2272 C CA  . ASN B 1 143 ? -47.69599 -29.57134 -8.41811  1.000 25.35089 ? 143 ASN B CA  1 
ATOM   2273 C C   . ASN B 1 143 ? -48.18231 -28.32407 -9.15544  1.000 19.89258 ? 143 ASN B C   1 
ATOM   2274 O O   . ASN B 1 143 ? -47.71031 -27.96338 -10.23591 1.000 24.37726 ? 143 ASN B O   1 
ATOM   2275 C CB  . ASN B 1 143 ? -46.56069 -30.24740 -9.17603  1.000 23.47761 ? 143 ASN B CB  1 
ATOM   2276 C CG  . ASN B 1 143 ? -45.80895 -31.26479 -8.32827  1.000 28.13398 ? 143 ASN B CG  1 
ATOM   2277 O OD1 . ASN B 1 143 ? -45.62738 -31.08952 -7.11934  1.000 22.57278 ? 143 ASN B OD1 1 
ATOM   2278 N ND2 . ASN B 1 143 ? -45.38331 -32.34730 -8.96238  1.000 25.41909 ? 143 ASN B ND2 1 
ATOM   2279 N N   . VAL B 1 144 ? -49.15232 -27.64969 -8.55064  1.000 21.86355 ? 144 VAL B N   1 
ATOM   2280 C CA  . VAL B 1 144 ? -49.74369 -26.43681 -9.10750  1.000 24.93012 ? 144 VAL B CA  1 
ATOM   2281 C C   . VAL B 1 144 ? -49.94345 -25.45039 -7.97011  1.000 33.02029 ? 144 VAL B C   1 
ATOM   2282 O O   . VAL B 1 144 ? -50.53791 -25.79389 -6.94309  1.000 31.21183 ? 144 VAL B O   1 
ATOM   2283 C CB  . VAL B 1 144 ? -51.08480 -26.70313 -9.81896  1.000 23.71111 ? 144 VAL B CB  1 
ATOM   2284 C CG1 . VAL B 1 144 ? -51.55067 -25.44920 -10.53550 1.000 31.50331 ? 144 VAL B CG1 1 
ATOM   2285 C CG2 . VAL B 1 144 ? -50.94998 -27.83436 -10.81613 1.000 25.91634 ? 144 VAL B CG2 1 
ATOM   2286 N N   . ASP B 1 145 ? -49.43284 -24.23724 -8.14017  1.000 31.01120 ? 145 ASP B N   1 
ATOM   2287 C CA  . ASP B 1 145 ? -49.61460 -23.16556 -7.16495  1.000 35.94122 ? 145 ASP B CA  1 
ATOM   2288 C C   . ASP B 1 145 ? -50.23904 -21.99804 -7.92390  1.000 41.17307 ? 145 ASP B C   1 
ATOM   2289 O O   . ASP B 1 145 ? -49.53006 -21.22272 -8.57680  1.000 43.45873 ? 145 ASP B O   1 
ATOM   2290 C CB  . ASP B 1 145 ? -48.29290 -22.78280 -6.50245  1.000 35.26639 ? 145 ASP B CB  1 
ATOM   2291 C CG  . ASP B 1 145 ? -48.40807 -21.53187 -5.65016  1.000 41.70568 ? 145 ASP B CG  1 
ATOM   2292 O OD1 . ASP B 1 145 ? -49.53079 -21.22573 -5.19423  1.000 47.11518 ? 145 ASP B OD1 1 
ATOM   2293 O OD2 . ASP B 1 145 ? -47.38093 -20.84948 -5.44676  1.000 28.23974 ? 145 ASP B OD2 1 
ATOM   2294 N N   . VAL B 1 146 ? -51.56362 -21.88542 -7.83379  1.000 41.11416 ? 146 VAL B N   1 
ATOM   2295 C CA  . VAL B 1 146 ? -52.34134 -20.89436 -8.57957  1.000 49.15221 ? 146 VAL B CA  1 
ATOM   2296 C C   . VAL B 1 146 ? -51.98384 -20.94957 -10.05910 1.000 46.25803 ? 146 VAL B C   1 
ATOM   2297 O O   . VAL B 1 146 ? -52.85633 -20.85629 -10.92046 1.000 54.50672 ? 146 VAL B O   1 
ATOM   2298 C CB  . VAL B 1 146 ? -52.14561 -19.45923 -8.02424  1.000 53.19174 ? 146 VAL B CB  1 
ATOM   2299 C CG1 . VAL B 1 146 ? -53.32663 -18.57285 -8.41343  1.000 52.01134 ? 146 VAL B CG1 1 
ATOM   2300 C CG2 . VAL B 1 146 ? -51.96808 -19.47593 -6.50949  1.000 47.87435 ? 146 VAL B CG2 1 
ATOM   2301 N N   . PRO C 1 1   ? -20.03243 -38.89919 -23.53431 1.000 16.95529 ? 1   PRO C N   1 
ATOM   2302 C CA  . PRO C 1 1   ? -21.05013 -37.97134 -23.01875 1.000 13.20898 ? 1   PRO C CA  1 
ATOM   2303 C C   . PRO C 1 1   ? -20.73261 -37.44551 -21.63016 1.000 10.42200 ? 1   PRO C C   1 
ATOM   2304 O O   . PRO C 1 1   ? -19.85738 -37.97123 -20.93037 1.000 13.74977 ? 1   PRO C O   1 
ATOM   2305 C CB  . PRO C 1 1   ? -22.30047 -38.83528 -22.92476 1.000 13.58329 ? 1   PRO C CB  1 
ATOM   2306 C CG  . PRO C 1 1   ? -21.75358 -40.20045 -22.63996 1.000 14.30077 ? 1   PRO C CG  1 
ATOM   2307 C CD  . PRO C 1 1   ? -20.50617 -40.29502 -23.48807 1.000 15.86025 ? 1   PRO C CD  1 
ATOM   2308 N N   . VAL C 1 2   ? -21.46114 -36.41868 -21.21854 1.000 10.84986 ? 2   VAL C N   1 
ATOM   2309 C CA  . VAL C 1 2   ? -21.50669 -36.00431 -19.82064 1.000 10.10420 ? 2   VAL C CA  1 
ATOM   2310 C C   . VAL C 1 2   ? -22.96589 -36.01335 -19.40073 1.000 12.78045 ? 2   VAL C C   1 
ATOM   2311 O O   . VAL C 1 2   ? -23.80873 -35.39147 -20.05631 1.000 13.49645 ? 2   VAL C O   1 
ATOM   2312 C CB  . VAL C 1 2   ? -20.87663 -34.62048 -19.60348 1.000 13.26594 ? 2   VAL C CB  1 
ATOM   2313 C CG1 . VAL C 1 2   ? -21.05750 -34.18047 -18.15428 1.000 14.39884 ? 2   VAL C CG1 1 
ATOM   2314 C CG2 . VAL C 1 2   ? -19.40636 -34.68540 -19.93145 1.000 8.43321  ? 2   VAL C CG2 1 
ATOM   2315 N N   . TYR C 1 3   ? -23.26478 -36.73911 -18.33501 1.000 12.87663 ? 3   TYR C N   1 
ATOM   2316 C CA  . TYR C 1 3   ? -24.60496 -36.79740 -17.76409 1.000 14.29989 ? 3   TYR C CA  1 
ATOM   2317 C C   . TYR C 1 3   ? -24.57602 -36.00920 -16.46873 1.000 15.24905 ? 3   TYR C C   1 
ATOM   2318 O O   . TYR C 1 3   ? -23.92148 -36.41825 -15.50082 1.000 12.97432 ? 3   TYR C O   1 
ATOM   2319 C CB  . TYR C 1 3   ? -25.03418 -38.22866 -17.49775 1.000 9.49294  ? 3   TYR C CB  1 
ATOM   2320 C CG  . TYR C 1 3   ? -25.40082 -38.97443 -18.73907 1.000 12.57638 ? 3   TYR C CG  1 
ATOM   2321 C CD1 . TYR C 1 3   ? -26.68933 -38.90710 -19.23394 1.000 13.82092 ? 3   TYR C CD1 1 
ATOM   2322 C CD2 . TYR C 1 3   ? -24.47119 -39.76444 -19.41196 1.000 13.42930 ? 3   TYR C CD2 1 
ATOM   2323 C CE1 . TYR C 1 3   ? -27.04885 -39.59248 -20.36698 1.000 12.65933 ? 3   TYR C CE1 1 
ATOM   2324 C CE2 . TYR C 1 3   ? -24.83117 -40.46183 -20.56291 1.000 12.93804 ? 3   TYR C CE2 1 
ATOM   2325 C CZ  . TYR C 1 3   ? -26.12515 -40.36017 -21.02547 1.000 15.47369 ? 3   TYR C CZ  1 
ATOM   2326 O OH  . TYR C 1 3   ? -26.53707 -41.02933 -22.14776 1.000 15.08499 ? 3   TYR C OH  1 
ATOM   2327 N N   . MET C 1 4   ? -25.27057 -34.88205 -16.44963 1.000 12.97524 ? 4   MET C N   1 
ATOM   2328 C CA  . MET C 1 4   ? -25.24217 -34.02988 -15.28179 1.000 12.32305 ? 4   MET C CA  1 
ATOM   2329 C C   . MET C 1 4   ? -26.46142 -34.50766 -14.50375 1.000 15.24560 ? 4   MET C C   1 
ATOM   2330 O O   . MET C 1 4   ? -27.55231 -34.54317 -15.07026 1.000 13.38069 ? 4   MET C O   1 
ATOM   2331 C CB  . MET C 1 4   ? -25.39064 -32.57466 -15.70789 1.000 15.93770 ? 4   MET C CB  1 
ATOM   2332 C CG  . MET C 1 4   ? -24.13229 -32.21818 -16.46765 1.000 15.15277 ? 4   MET C CG  1 
ATOM   2333 S SD  . MET C 1 4   ? -22.58222 -31.95525 -15.69873 1.000 15.55525 ? 4   MET C SD  1 
ATOM   2334 C CE  . MET C 1 4   ? -22.98262 -31.47211 -14.02146 1.000 17.79721 ? 4   MET C CE  1 
ATOM   2335 N N   . VAL C 1 5   ? -26.29027 -34.96065 -13.26099 1.000 12.44841 ? 5   VAL C N   1 
ATOM   2336 C CA  . VAL C 1 5   ? -27.40492 -35.55043 -12.51737 1.000 11.83490 ? 5   VAL C CA  1 
ATOM   2337 C C   . VAL C 1 5   ? -27.69396 -34.67067 -11.30769 1.000 12.26871 ? 5   VAL C C   1 
ATOM   2338 O O   . VAL C 1 5   ? -26.88709 -34.61148 -10.37470 1.000 13.28725 ? 5   VAL C O   1 
ATOM   2339 C CB  . VAL C 1 5   ? -27.11045 -36.99141 -12.10049 1.000 14.55983 ? 5   VAL C CB  1 
ATOM   2340 C CG1 . VAL C 1 5   ? -28.30218 -37.55823 -11.34865 1.000 13.50435 ? 5   VAL C CG1 1 
ATOM   2341 C CG2 . VAL C 1 5   ? -26.78066 -37.84594 -13.34038 1.000 13.76727 ? 5   VAL C CG2 1 
ATOM   2342 N N   . TYR C 1 6   ? -28.84459 -34.00530 -11.31308 1.000 12.11367 ? 6   TYR C N   1 
ATOM   2343 C CA  . TYR C 1 6   ? -29.21182 -33.04781 -10.27363 1.000 10.13444 ? 6   TYR C CA  1 
ATOM   2344 C C   . TYR C 1 6   ? -30.09765 -33.72068 -9.23999  1.000 14.19025 ? 6   TYR C C   1 
ATOM   2345 O O   . TYR C 1 6   ? -31.20608 -34.15115 -9.55977  1.000 15.28167 ? 6   TYR C O   1 
ATOM   2346 C CB  . TYR C 1 6   ? -29.91581 -31.83761 -10.86883 1.000 9.67447  ? 6   TYR C CB  1 
ATOM   2347 C CG  . TYR C 1 6   ? -29.03263 -31.14251 -11.86772 1.000 12.80465 ? 6   TYR C CG  1 
ATOM   2348 C CD1 . TYR C 1 6   ? -28.08473 -30.21826 -11.44689 1.000 14.09626 ? 6   TYR C CD1 1 
ATOM   2349 C CD2 . TYR C 1 6   ? -29.12158 -31.43466 -13.22385 1.000 13.54571 ? 6   TYR C CD2 1 
ATOM   2350 C CE1 . TYR C 1 6   ? -27.24429 -29.58498 -12.36934 1.000 13.21316 ? 6   TYR C CE1 1 
ATOM   2351 C CE2 . TYR C 1 6   ? -28.30694 -30.79800 -14.15088 1.000 12.33255 ? 6   TYR C CE2 1 
ATOM   2352 C CZ  . TYR C 1 6   ? -27.37305 -29.87844 -13.71048 1.000 11.68913 ? 6   TYR C CZ  1 
ATOM   2353 O OH  . TYR C 1 6   ? -26.54938 -29.23204 -14.60181 1.000 13.12524 ? 6   TYR C OH  1 
ATOM   2354 N N   . VAL C 1 7   ? -29.59745 -33.81456 -8.00715  1.000 14.49401 ? 7   VAL C N   1 
ATOM   2355 C CA  . VAL C 1 7   ? -30.27953 -34.53033 -6.93476  1.000 14.35563 ? 7   VAL C CA  1 
ATOM   2356 C C   . VAL C 1 7   ? -30.18320 -33.70782 -5.66062  1.000 18.13239 ? 7   VAL C C   1 
ATOM   2357 O O   . VAL C 1 7   ? -29.37017 -32.78638 -5.54683  1.000 15.74606 ? 7   VAL C O   1 
ATOM   2358 C CB  . VAL C 1 7   ? -29.68102 -35.94025 -6.70698  1.000 14.67230 ? 7   VAL C CB  1 
ATOM   2359 C CG1 . VAL C 1 7   ? -29.98732 -36.85547 -7.89772  1.000 16.81067 ? 7   VAL C CG1 1 
ATOM   2360 C CG2 . VAL C 1 7   ? -28.16947 -35.82372 -6.51899  1.000 18.59386 ? 7   VAL C CG2 1 
ATOM   2361 N N   . SER C 1 8   ? -31.01503 -34.06676 -4.68270  1.000 16.93021 ? 8   SER C N   1 
ATOM   2362 C CA  . SER C 1 8   ? -30.93848 -33.42513 -3.37399  1.000 16.50807 ? 8   SER C CA  1 
ATOM   2363 C C   . SER C 1 8   ? -29.81253 -34.01408 -2.53106  1.000 20.59949 ? 8   SER C C   1 
ATOM   2364 O O   . SER C 1 8   ? -29.52209 -35.21244 -2.59283  1.000 19.29990 ? 8   SER C O   1 
ATOM   2365 C CB  . SER C 1 8   ? -32.27367 -33.55806 -2.64316  1.000 17.50108 ? 8   SER C CB  1 
ATOM   2366 O OG  . SER C 1 8   ? -33.28266 -32.86145 -3.33632  1.000 21.26269 ? 8   SER C OG  1 
ATOM   2367 N N   . GLN C 1 9   ? -29.16561 -33.15347 -1.74467  1.000 18.56367 ? 9   GLN C N   1 
ATOM   2368 C CA  . GLN C 1 9   ? -28.12336 -33.59786 -0.83171  1.000 21.82384 ? 9   GLN C CA  1 
ATOM   2369 C C   . GLN C 1 9   ? -28.64528 -34.73526 0.04941   1.000 24.87488 ? 9   GLN C C   1 
ATOM   2370 O O   . GLN C 1 9   ? -29.75521 -34.66803 0.57817   1.000 24.06882 ? 9   GLN C O   1 
ATOM   2371 C CB  . GLN C 1 9   ? -27.66701 -32.40875 0.01597   1.000 26.01954 ? 9   GLN C CB  1 
ATOM   2372 C CG  . GLN C 1 9   ? -26.73876 -32.73520 1.16154   1.000 29.79088 ? 9   GLN C CG  1 
ATOM   2373 C CD  . GLN C 1 9   ? -25.28646 -32.75582 0.74292   1.000 40.93154 ? 9   GLN C CD  1 
ATOM   2374 O OE1 . GLN C 1 9   ? -24.93735 -32.31717 -0.35752  1.000 39.42615 ? 9   GLN C OE1 1 
ATOM   2375 N NE2 . GLN C 1 9   ? -24.42452 -33.24954 1.62559   1.000 41.84415 ? 9   GLN C NE2 1 
ATOM   2376 N N   . ASP C 1 10  ? -27.86751 -35.80930 0.14314   1.000 30.89048 ? 10  ASP C N   1 
ATOM   2377 C CA  . ASP C 1 10  ? -28.08021 -36.97213 0.99787   1.000 30.04653 ? 10  ASP C CA  1 
ATOM   2378 C C   . ASP C 1 10  ? -29.12724 -37.94479 0.44771   1.000 27.71958 ? 10  ASP C C   1 
ATOM   2379 O O   . ASP C 1 10  ? -29.30272 -39.01504 1.02996   1.000 28.98982 ? 10  ASP C O   1 
ATOM   2380 C CB  . ASP C 1 10  ? -28.48047 -36.59903 2.43845   1.000 36.76278 ? 10  ASP C CB  1 
ATOM   2381 C CG  . ASP C 1 10  ? -27.36087 -35.91100 3.18936   1.000 39.88976 ? 10  ASP C CG  1 
ATOM   2382 O OD1 . ASP C 1 10  ? -26.20425 -35.95624 2.71178   1.000 45.34372 ? 10  ASP C OD1 1 
ATOM   2383 O OD2 . ASP C 1 10  ? -27.64242 -35.31433 4.24977   1.000 55.27634 ? 10  ASP C OD2 1 
ATOM   2384 N N   . ARG C 1 11  ? -29.83404 -37.62014 -0.64022  1.000 21.01179 ? 11  ARG C N   1 
ATOM   2385 C CA  . ARG C 1 11  ? -30.83749 -38.54164 -1.16254  1.000 18.20563 ? 11  ARG C CA  1 
ATOM   2386 C C   . ARG C 1 11  ? -30.19586 -39.84504 -1.62167  1.000 20.14461 ? 11  ARG C C   1 
ATOM   2387 O O   . ARG C 1 11  ? -30.76095 -40.92651 -1.42906  1.000 24.67505 ? 11  ARG C O   1 
ATOM   2388 C CB  . ARG C 1 11  ? -31.60519 -37.89969 -2.31303  1.000 22.71894 ? 11  ARG C CB  1 
ATOM   2389 C CG  . ARG C 1 11  ? -32.55064 -38.85142 -3.03678  1.000 22.29602 ? 11  ARG C CG  1 
ATOM   2390 C CD  . ARG C 1 11  ? -33.69668 -39.29634 -2.13068  1.000 27.33025 ? 11  ARG C CD  1 
ATOM   2391 N NE  . ARG C 1 11  ? -34.59356 -40.24997 -2.78169  1.000 23.59439 ? 11  ARG C NE  1 
ATOM   2392 C CZ  . ARG C 1 11  ? -34.23628 -41.45411 -3.21355  1.000 28.77917 ? 11  ARG C CZ  1 
ATOM   2393 N NH1 . ARG C 1 11  ? -33.02397 -41.94234 -2.99085  1.000 28.07005 ? 11  ARG C NH1 1 
ATOM   2394 N NH2 . ARG C 1 11  ? -35.12436 -42.20037 -3.86537  1.000 29.08443 ? 11  ARG C NH2 1 
ATOM   2395 N N   . LEU C 1 12  ? -29.01609 -39.76343 -2.22717  1.000 21.01375 ? 12  LEU C N   1 
ATOM   2396 C CA  . LEU C 1 12  ? -28.26952 -40.93148 -2.66474  1.000 19.36247 ? 12  LEU C CA  1 
ATOM   2397 C C   . LEU C 1 12  ? -27.05657 -41.10953 -1.76888  1.000 20.21741 ? 12  LEU C C   1 
ATOM   2398 O O   . LEU C 1 12  ? -26.27189 -40.17179 -1.58553  1.000 22.40875 ? 12  LEU C O   1 
ATOM   2399 C CB  . LEU C 1 12  ? -27.80633 -40.78690 -4.11714  1.000 21.69548 ? 12  LEU C CB  1 
ATOM   2400 C CG  . LEU C 1 12  ? -28.87044 -40.55788 -5.18258  1.000 22.25598 ? 12  LEU C CG  1 
ATOM   2401 C CD1 . LEU C 1 12  ? -28.18840 -40.41245 -6.55463  1.000 18.28342 ? 12  LEU C CD1 1 
ATOM   2402 C CD2 . LEU C 1 12  ? -29.89021 -41.67727 -5.19319  1.000 22.67408 ? 12  LEU C CD2 1 
ATOM   2403 N N   . THR C 1 13  ? -26.89677 -42.31038 -1.22592  1.000 20.63757 ? 13  THR C N   1 
ATOM   2404 C CA  . THR C 1 13  ? -25.67910 -42.65830 -0.53395  1.000 19.69156 ? 13  THR C CA  1 
ATOM   2405 C C   . THR C 1 13  ? -24.54814 -42.78095 -1.55038  1.000 26.10069 ? 13  THR C C   1 
ATOM   2406 O O   . THR C 1 13  ? -24.79747 -42.81734 -2.76019  1.000 23.50965 ? 13  THR C O   1 
ATOM   2407 C CB  . THR C 1 13  ? -25.86338 -43.97223 0.22377   1.000 23.45515 ? 13  THR C CB  1 
ATOM   2408 O OG1 . THR C 1 13  ? -26.08016 -45.03323 -0.71195  1.000 21.06971 ? 13  THR C OG1 1 
ATOM   2409 C CG2 . THR C 1 13  ? -27.05580 -43.87579 1.14913   1.000 22.06972 ? 13  THR C CG2 1 
ATOM   2410 N N   . PRO C 1 14  ? -23.28683 -42.83533 -1.09213  1.000 21.25134 ? 14  PRO C N   1 
ATOM   2411 C CA  . PRO C 1 14  ? -22.19224 -43.15619 -2.02313  1.000 25.85440 ? 14  PRO C CA  1 
ATOM   2412 C C   . PRO C 1 14  ? -22.45363 -44.41743 -2.81651  1.000 23.60050 ? 14  PRO C C   1 
ATOM   2413 O O   . PRO C 1 14  ? -22.16775 -44.46777 -4.02060  1.000 23.48219 ? 14  PRO C O   1 
ATOM   2414 C CB  . PRO C 1 14  ? -20.98137 -43.31561 -1.09400  1.000 26.97702 ? 14  PRO C CB  1 
ATOM   2415 C CG  . PRO C 1 14  ? -21.28511 -42.42902 0.06649   1.000 28.01415 ? 14  PRO C CG  1 
ATOM   2416 C CD  . PRO C 1 14  ? -22.77698 -42.48928 0.25519   1.000 24.98285 ? 14  PRO C CD  1 
ATOM   2417 N N   . SER C 1 15  ? -23.02434 -45.43589 -2.16616  1.000 22.82761 ? 15  SER C N   1 
ATOM   2418 C CA  . SER C 1 15  ? -23.36918 -46.67450 -2.85738  1.000 19.58424 ? 15  SER C CA  1 
ATOM   2419 C C   . SER C 1 15  ? -24.43292 -46.43953 -3.92245  1.000 17.48774 ? 15  SER C C   1 
ATOM   2420 O O   . SER C 1 15  ? -24.33541 -46.97128 -5.03537  1.000 20.59611 ? 15  SER C O   1 
ATOM   2421 C CB  . SER C 1 15  ? -23.85524 -47.71347 -1.84332  1.000 24.10795 ? 15  SER C CB  1 
ATOM   2422 O OG  . SER C 1 15  ? -24.14046 -48.93894 -2.49174  1.000 35.75141 ? 15  SER C OG  1 
ATOM   2423 N N   . ALA C 1 16  ? -25.47371 -45.67089 -3.58713  1.000 19.13782 ? 16  ALA C N   1 
ATOM   2424 C CA  . ALA C 1 16  ? -26.54508 -45.40381 -4.53613  1.000 19.99835 ? 16  ALA C CA  1 
ATOM   2425 C C   . ALA C 1 16  ? -26.05169 -44.55893 -5.69808  1.000 19.60439 ? 16  ALA C C   1 
ATOM   2426 O O   . ALA C 1 16  ? -26.50005 -44.74913 -6.83398  1.000 15.74795 ? 16  ALA C O   1 
ATOM   2427 C CB  . ALA C 1 16  ? -27.71945 -44.71158 -3.83732  1.000 18.93416 ? 16  ALA C CB  1 
ATOM   2428 N N   . LYS C 1 17  ? -25.13450 -43.62142 -5.43110  1.000 20.07556 ? 17  LYS C N   1 
ATOM   2429 C CA  . LYS C 1 17  ? -24.53406 -42.82621 -6.50176  1.000 18.94443 ? 17  LYS C CA  1 
ATOM   2430 C C   . LYS C 1 17  ? -23.73255 -43.70548 -7.44330  1.000 18.13840 ? 17  LYS C C   1 
ATOM   2431 O O   . LYS C 1 17  ? -23.80087 -43.54778 -8.66539  1.000 18.74889 ? 17  LYS C O   1 
ATOM   2432 C CB  . LYS C 1 17  ? -23.62365 -41.75079 -5.91189  1.000 17.70933 ? 17  LYS C CB  1 
ATOM   2433 C CG  . LYS C 1 17  ? -24.35634 -40.57328 -5.29443  1.000 21.34246 ? 17  LYS C CG  1 
ATOM   2434 C CD  . LYS C 1 17  ? -23.34985 -39.56214 -4.78227  1.000 22.56103 ? 17  LYS C CD  1 
ATOM   2435 C CE  . LYS C 1 17  ? -24.02492 -38.47962 -3.96536  1.000 22.01558 ? 17  LYS C CE  1 
ATOM   2436 N NZ  . LYS C 1 17  ? -23.01665 -37.78237 -3.13279  1.000 26.71546 ? 17  LYS C NZ  1 
ATOM   2437 N N   . HIS C 1 18  ? -22.94961 -44.63073 -6.88565  1.000 16.76869 ? 18  HIS C N   1 
ATOM   2438 C CA  . HIS C 1 18  ? -22.24107 -45.59669 -7.71486  1.000 18.88078 ? 18  HIS C CA  1 
ATOM   2439 C C   . HIS C 1 18  ? -23.21240 -46.40038 -8.57092  1.000 19.44089 ? 18  HIS C C   1 
ATOM   2440 O O   . HIS C 1 18  ? -22.96491 -46.64836 -9.75924  1.000 18.21234 ? 18  HIS C O   1 
ATOM   2441 C CB  . HIS C 1 18  ? -21.41821 -46.52291 -6.81935  1.000 20.94680 ? 18  HIS C CB  1 
ATOM   2442 C CG  . HIS C 1 18  ? -20.44270 -47.37602 -7.56573  1.000 25.89178 ? 18  HIS C CG  1 
ATOM   2443 N ND1 . HIS C 1 18  ? -19.91807 -47.01656 -8.78849  1.000 33.76161 ? 18  HIS C ND1 1 
ATOM   2444 C CD2 . HIS C 1 18  ? -19.92522 -48.59344 -7.27939  1.000 36.48082 ? 18  HIS C CD2 1 
ATOM   2445 C CE1 . HIS C 1 18  ? -19.09487 -47.96239 -9.20722  1.000 25.82053 ? 18  HIS C CE1 1 
ATOM   2446 N NE2 . HIS C 1 18  ? -19.08466 -48.93163 -8.31263  1.000 37.61478 ? 18  HIS C NE2 1 
ATOM   2447 N N   . ALA C 1 19  ? -24.31854 -46.83960 -7.97348  1.000 15.06948 ? 19  ALA C N   1 
ATOM   2448 C CA  . ALA C 1 19  ? -25.27747 -47.64852 -8.70884  1.000 14.79506 ? 19  ALA C CA  1 
ATOM   2449 C C   . ALA C 1 19  ? -25.92326 -46.84344 -9.82328  1.000 15.99278 ? 19  ALA C C   1 
ATOM   2450 O O   . ALA C 1 19  ? -26.04992 -47.32709 -10.95399 1.000 16.36634 ? 19  ALA C O   1 
ATOM   2451 C CB  . ALA C 1 19  ? -26.33434 -48.20343 -7.75305  1.000 20.66301 ? 19  ALA C CB  1 
ATOM   2452 N N   . VAL C 1 20  ? -26.31495 -45.60364 -9.52389  1.000 16.27280 ? 20  VAL C N   1 
ATOM   2453 C CA  . VAL C 1 20  ? -26.92699 -44.74410 -10.53612 1.000 16.43790 ? 20  VAL C CA  1 
ATOM   2454 C C   . VAL C 1 20  ? -25.94288 -44.46213 -11.67062 1.000 15.41650 ? 20  VAL C C   1 
ATOM   2455 O O   . VAL C 1 20  ? -26.31409 -44.50647 -12.85085 1.000 14.54292 ? 20  VAL C O   1 
ATOM   2456 C CB  . VAL C 1 20  ? -27.44688 -43.45126 -9.87370  1.000 16.23629 ? 20  VAL C CB  1 
ATOM   2457 C CG1 . VAL C 1 20  ? -27.79590 -42.40113 -10.91596 1.000 13.49630 ? 20  VAL C CG1 1 
ATOM   2458 C CG2 . VAL C 1 20  ? -28.68718 -43.76241 -9.00922  1.000 13.74527 ? 20  VAL C CG2 1 
ATOM   2459 N N   . ALA C 1 21  ? -24.67888 -44.16476 -11.33143 1.000 15.08224 ? 21  ALA C N   1 
ATOM   2460 C CA  . ALA C 1 21  ? -23.66988 -43.89893 -12.35871 1.000 16.15435 ? 21  ALA C CA  1 
ATOM   2461 C C   . ALA C 1 21  ? -23.44201 -45.12280 -13.23390 1.000 19.98402 ? 21  ALA C C   1 
ATOM   2462 O O   . ALA C 1 21  ? -23.27181 -45.00429 -14.44991 1.000 16.42756 ? 21  ALA C O   1 
ATOM   2463 C CB  . ALA C 1 21  ? -22.35680 -43.45651 -11.71752 1.000 15.83486 ? 21  ALA C CB  1 
ATOM   2464 N N   . LYS C 1 22  ? -23.45780 -46.31253 -12.63295 1.000 15.63896 ? 22  LYS C N   1 
ATOM   2465 C CA  . LYS C 1 22  ? -23.26948 -47.52614 -13.41401 1.000 17.49345 ? 22  LYS C CA  1 
ATOM   2466 C C   . LYS C 1 22  ? -24.47829 -47.79018 -14.31247 1.000 19.12044 ? 22  LYS C C   1 
ATOM   2467 O O   . LYS C 1 22  ? -24.32038 -48.18363 -15.47483 1.000 21.51805 ? 22  LYS C O   1 
ATOM   2468 C CB  . LYS C 1 22  ? -22.99577 -48.69826 -12.46268 1.000 22.09961 ? 22  LYS C CB  1 
ATOM   2469 C CG  . LYS C 1 22  ? -22.86543 -50.03292 -13.15911 1.000 29.74867 ? 22  LYS C CG  1 
ATOM   2470 C CD  . LYS C 1 22  ? -22.26974 -51.08823 -12.23247 1.000 37.50929 ? 22  LYS C CD  1 
ATOM   2471 C CE  . LYS C 1 22  ? -21.33231 -52.00943 -13.02059 1.000 42.66138 ? 22  LYS C CE  1 
ATOM   2472 N NZ  . LYS C 1 22  ? -22.05836 -53.01544 -13.84632 1.000 39.30797 ? 22  LYS C NZ  1 
ATOM   2473 N N   . ALA C 1 23  ? -25.68800 -47.56373 -13.79416 1.000 17.11883 ? 23  ALA C N   1 
ATOM   2474 C CA  . ALA C 1 23  ? -26.90423 -47.70633 -14.58659 1.000 17.98429 ? 23  ALA C CA  1 
ATOM   2475 C C   . ALA C 1 23  ? -26.86894 -46.81743 -15.82780 1.000 18.19598 ? 23  ALA C C   1 
ATOM   2476 O O   . ALA C 1 23  ? -27.20428 -47.26177 -16.93016 1.000 17.05231 ? 23  ALA C O   1 
ATOM   2477 C CB  . ALA C 1 23  ? -28.12481 -47.36919 -13.73300 1.000 20.86122 ? 23  ALA C CB  1 
ATOM   2478 N N   . ILE C 1 24  ? -26.45517 -45.55468 -15.66897 1.000 15.92937 ? 24  ILE C N   1 
ATOM   2479 C CA  . ILE C 1 24  ? -26.43584 -44.63904 -16.80901 1.000 16.10632 ? 24  ILE C CA  1 
ATOM   2480 C C   . ILE C 1 24  ? -25.32332 -45.02047 -17.77522 1.000 18.01334 ? 24  ILE C C   1 
ATOM   2481 O O   . ILE C 1 24  ? -25.53398 -45.10793 -18.99232 1.000 13.58122 ? 24  ILE C O   1 
ATOM   2482 C CB  . ILE C 1 24  ? -26.29402 -43.18688 -16.31910 1.000 13.99955 ? 24  ILE C CB  1 
ATOM   2483 C CG1 . ILE C 1 24  ? -27.53885 -42.79232 -15.50958 1.000 15.97116 ? 24  ILE C CG1 1 
ATOM   2484 C CG2 . ILE C 1 24  ? -26.05927 -42.24691 -17.49217 1.000 14.59953 ? 24  ILE C CG2 1 
ATOM   2485 C CD1 . ILE C 1 24  ? -27.41735 -41.43818 -14.78975 1.000 16.86541 ? 24  ILE C CD1 1 
ATOM   2486 N N   . THR C 1 25  ? -24.12988 -45.27692 -17.23765 1.000 14.66818 ? 25  THR C N   1 
ATOM   2487 C CA  . THR C 1 25  ? -22.98642 -45.63752 -18.06599 1.000 16.92739 ? 25  THR C CA  1 
ATOM   2488 C C   . THR C 1 25  ? -23.25283 -46.92665 -18.84280 1.000 17.61848 ? 25  THR C C   1 
ATOM   2489 O O   . THR C 1 25  ? -23.02197 -46.99215 -20.05615 1.000 14.25322 ? 25  THR C O   1 
ATOM   2490 C CB  . THR C 1 25  ? -21.74863 -45.77766 -17.18279 1.000 14.71152 ? 25  THR C CB  1 
ATOM   2491 O OG1 . THR C 1 25  ? -21.50451 -44.54256 -16.49358 1.000 15.91348 ? 25  THR C OG1 1 
ATOM   2492 C CG2 . THR C 1 25  ? -20.52524 -46.14405 -18.00913 1.000 14.04067 ? 25  THR C CG2 1 
ATOM   2493 N N   . ASP C 1 26  ? -23.75170 -47.96443 -18.15620 1.000 16.89506 ? 26  ASP C N   1 
ATOM   2494 C CA  . ASP C 1 26  ? -24.06153 -49.22275 -18.83454 1.000 18.92418 ? 26  ASP C CA  1 
ATOM   2495 C C   . ASP C 1 26  ? -25.11586 -49.02494 -19.91971 1.000 18.70474 ? 26  ASP C C   1 
ATOM   2496 O O   . ASP C 1 26  ? -25.04374 -49.64601 -20.98609 1.000 16.37785 ? 26  ASP C O   1 
ATOM   2497 C CB  . ASP C 1 26  ? -24.54807 -50.26940 -17.82890 1.000 18.92029 ? 26  ASP C CB  1 
ATOM   2498 C CG  . ASP C 1 26  ? -23.43517 -50.80572 -16.94824 1.000 23.66894 ? 26  ASP C CG  1 
ATOM   2499 O OD1 . ASP C 1 26  ? -22.24969 -50.50250 -17.22708 1.000 22.57904 ? 26  ASP C OD1 1 
ATOM   2500 O OD2 . ASP C 1 26  ? -23.75550 -51.54079 -15.97862 1.000 24.65868 ? 26  ASP C OD2 1 
ATOM   2501 N N   . ALA C 1 27  ? -26.10759 -48.16874 -19.66615 1.000 18.94891 ? 27  ALA C N   1 
ATOM   2502 C CA  . ALA C 1 27  ? -27.11006 -47.88355 -20.68945 1.000 17.36470 ? 27  ALA C CA  1 
ATOM   2503 C C   . ALA C 1 27  ? -26.47988 -47.20573 -21.89931 1.000 17.52600 ? 27  ALA C C   1 
ATOM   2504 O O   . ALA C 1 27  ? -26.79932 -47.53637 -23.05105 1.000 15.85025 ? 27  ALA C O   1 
ATOM   2505 C CB  . ALA C 1 27  ? -28.22114 -47.00183 -20.10951 1.000 17.42309 ? 27  ALA C CB  1 
ATOM   2506 N N   . HIS C 1 28  ? -25.60287 -46.23322 -21.65669 1.000 14.56442 ? 28  HIS C N   1 
ATOM   2507 C CA  . HIS C 1 28  ? -25.04307 -45.47934 -22.76167 1.000 14.96311 ? 28  HIS C CA  1 
ATOM   2508 C C   . HIS C 1 28  ? -24.16737 -46.38157 -23.61821 1.000 19.24535 ? 28  HIS C C   1 
ATOM   2509 O O   . HIS C 1 28  ? -24.27624 -46.38544 -24.84960 1.000 20.63371 ? 28  HIS C O   1 
ATOM   2510 C CB  . HIS C 1 28  ? -24.26206 -44.27199 -22.24145 1.000 18.56476 ? 28  HIS C CB  1 
ATOM   2511 C CG  . HIS C 1 28  ? -23.87429 -43.32028 -23.32529 1.000 15.57483 ? 28  HIS C CG  1 
ATOM   2512 N ND1 . HIS C 1 28  ? -24.65073 -42.23010 -23.66491 1.000 14.68456 ? 28  HIS C ND1 1 
ATOM   2513 C CD2 . HIS C 1 28  ? -22.84425 -43.34181 -24.20409 1.000 16.13093 ? 28  HIS C CD2 1 
ATOM   2514 C CE1 . HIS C 1 28  ? -24.09715 -41.60432 -24.68796 1.000 19.05243 ? 28  HIS C CE1 1 
ATOM   2515 N NE2 . HIS C 1 28  ? -23.00025 -42.25748 -25.03249 1.000 18.92624 ? 28  HIS C NE2 1 
ATOM   2516 N N   A ARG C 1 29  ? -23.28801 -47.16064 -22.98765 0.287 16.33905 ? 29  ARG C N   1 
ATOM   2517 N N   B ARG C 1 29  ? -23.31203 -47.18016 -22.97631 0.713 16.18556 ? 29  ARG C N   1 
ATOM   2518 C CA  A ARG C 1 29  ? -22.43813 -48.05955 -23.76279 0.287 20.14115 ? 29  ARG C CA  1 
ATOM   2519 C CA  B ARG C 1 29  ? -22.42226 -48.07173 -23.72068 0.713 20.14005 ? 29  ARG C CA  1 
ATOM   2520 C C   A ARG C 1 29  ? -23.27247 -49.08556 -24.51795 0.287 20.90557 ? 29  ARG C C   1 
ATOM   2521 C C   B ARG C 1 29  ? -23.20618 -49.15026 -24.46283 0.713 20.92154 ? 29  ARG C C   1 
ATOM   2522 O O   A ARG C 1 29  ? -23.00619 -49.37450 -25.69059 0.287 20.21374 ? 29  ARG C O   1 
ATOM   2523 O O   B ARG C 1 29  ? -22.84273 -49.53158 -25.58250 0.713 19.88226 ? 29  ARG C O   1 
ATOM   2524 C CB  A ARG C 1 29  ? -21.45809 -48.78750 -22.85164 0.287 21.49053 ? 29  ARG C CB  1 
ATOM   2525 C CB  B ARG C 1 29  ? -21.41447 -48.70814 -22.76170 0.713 21.38970 ? 29  ARG C CB  1 
ATOM   2526 C CG  A ARG C 1 29  ? -22.16679 -49.84456 -22.04099 0.287 22.57659 ? 29  ARG C CG  1 
ATOM   2527 C CG  B ARG C 1 29  ? -21.01187 -50.13209 -23.13572 0.713 24.05435 ? 29  ARG C CG  1 
ATOM   2528 C CD  A ARG C 1 29  ? -21.26801 -50.64730 -21.24639 0.287 27.56257 ? 29  ARG C CD  1 
ATOM   2529 C CD  B ARG C 1 29  ? -19.51455 -50.34421 -23.00969 0.713 26.67763 ? 29  ARG C CD  1 
ATOM   2530 N NE  A ARG C 1 29  ? -21.93903 -51.62966 -20.40365 0.287 25.09878 ? 29  ARG C NE  1 
ATOM   2531 N NE  B ARG C 1 29  ? -18.96126 -51.18056 -24.07032 0.713 35.82659 ? 29  ARG C NE  1 
ATOM   2532 C CZ  A ARG C 1 29  ? -22.07676 -52.90992 -20.71785 0.287 27.51273 ? 29  ARG C CZ  1 
ATOM   2533 C CZ  B ARG C 1 29  ? -17.67118 -51.22817 -24.38373 0.713 40.51134 ? 29  ARG C CZ  1 
ATOM   2534 N NH1 A ARG C 1 29  ? -21.59169 -53.40038 -21.84737 0.287 27.95948 ? 29  ARG C NH1 1 
ATOM   2535 N NH1 B ARG C 1 29  ? -16.76856 -50.51933 -23.71775 0.713 38.08606 ? 29  ARG C NH1 1 
ATOM   2536 N NH2 A ARG C 1 29  ? -22.70085 -53.72206 -19.87042 0.287 28.11413 ? 29  ARG C NH2 1 
ATOM   2537 N NH2 B ARG C 1 29  ? -17.27379 -52.01566 -25.37997 0.713 47.54573 ? 29  ARG C NH2 1 
ATOM   2538 N N   . GLY C 1 30  ? -24.28730 -49.65041 -23.85669 1.000 21.15108 ? 30  GLY C N   1 
ATOM   2539 C CA  . GLY C 1 30  ? -25.01096 -50.75922 -24.43939 1.000 22.63345 ? 30  GLY C CA  1 
ATOM   2540 C C   . GLY C 1 30  ? -25.81253 -50.34204 -25.64245 1.000 24.03040 ? 30  GLY C C   1 
ATOM   2541 O O   . GLY C 1 30  ? -25.95214 -51.10987 -26.60020 1.000 21.86486 ? 30  GLY C O   1 
ATOM   2542 N N   . LEU C 1 31  ? -26.31460 -49.11498 -25.63586 1.000 18.28140 ? 31  LEU C N   1 
ATOM   2543 C CA  . LEU C 1 31  ? -27.13327 -48.67030 -26.74788 1.000 18.15904 ? 31  LEU C CA  1 
ATOM   2544 C C   . LEU C 1 31  ? -26.34273 -47.91836 -27.81290 1.000 23.23425 ? 31  LEU C C   1 
ATOM   2545 O O   . LEU C 1 31  ? -26.78833 -47.87977 -28.96275 1.000 20.31902 ? 31  LEU C O   1 
ATOM   2546 C CB  . LEU C 1 31  ? -28.28912 -47.80412 -26.23497 1.000 18.09379 ? 31  LEU C CB  1 
ATOM   2547 C CG  . LEU C 1 31  ? -29.39712 -48.62065 -25.55967 1.000 21.47174 ? 31  LEU C CG  1 
ATOM   2548 C CD1 . LEU C 1 31  ? -30.32469 -47.74641 -24.75182 1.000 21.28137 ? 31  LEU C CD1 1 
ATOM   2549 C CD2 . LEU C 1 31  ? -30.17480 -49.40107 -26.60296 1.000 25.96702 ? 31  LEU C CD2 1 
ATOM   2550 N N   . THR C 1 32  ? -25.18473 -47.33091 -27.47606 1.000 18.14709 ? 32  THR C N   1 
ATOM   2551 C CA  . THR C 1 32  ? -24.42377 -46.55273 -28.45043 1.000 18.29211 ? 32  THR C CA  1 
ATOM   2552 C C   . THR C 1 32  ? -23.11512 -47.19669 -28.87383 1.000 21.13856 ? 32  THR C C   1 
ATOM   2553 O O   . THR C 1 32  ? -22.51311 -46.73432 -29.84578 1.000 23.69477 ? 32  THR C O   1 
ATOM   2554 C CB  . THR C 1 32  ? -24.05811 -45.15468 -27.92195 1.000 21.09988 ? 32  THR C CB  1 
ATOM   2555 O OG1 . THR C 1 32  ? -23.05815 -45.28079 -26.89875 1.000 19.28000 ? 32  THR C OG1 1 
ATOM   2556 C CG2 . THR C 1 32  ? -25.27457 -44.41851 -27.37080 1.000 18.43442 ? 32  THR C CG2 1 
ATOM   2557 N N   . GLY C 1 33  ? -22.62485 -48.19626 -28.14358 1.000 22.10561 ? 33  GLY C N   1 
ATOM   2558 C CA  . GLY C 1 33  ? -21.30395 -48.73510 -28.40932 1.000 20.98370 ? 33  GLY C CA  1 
ATOM   2559 C C   . GLY C 1 33  ? -20.14494 -47.89912 -27.90530 1.000 23.02056 ? 33  GLY C C   1 
ATOM   2560 O O   . GLY C 1 33  ? -18.99949 -48.36135 -27.97687 1.000 28.29499 ? 33  GLY C O   1 
ATOM   2561 N N   . THR C 1 34  ? -20.39275 -46.68467 -27.41592 1.000 22.31781 ? 34  THR C N   1 
ATOM   2562 C CA  . THR C 1 34  ? -19.33705 -45.85601 -26.83826 1.000 22.31679 ? 34  THR C CA  1 
ATOM   2563 C C   . THR C 1 34  ? -18.72376 -46.53319 -25.61563 1.000 22.76058 ? 34  THR C C   1 
ATOM   2564 O O   . THR C 1 34  ? -19.43194 -47.06930 -24.75820 1.000 26.48784 ? 34  THR C O   1 
ATOM   2565 C CB  . THR C 1 34  ? -19.90379 -44.47482 -26.45835 1.000 23.34333 ? 34  THR C CB  1 
ATOM   2566 O OG1 . THR C 1 34  ? -20.38239 -43.80517 -27.63701 1.000 28.93086 ? 34  THR C OG1 1 
ATOM   2567 C CG2 . THR C 1 34  ? -18.87225 -43.59857 -25.76211 1.000 26.78058 ? 34  THR C CG2 1 
ATOM   2568 N N   . GLN C 1 35  ? -17.39386 -46.49945 -25.53739 1.000 22.86865 ? 35  GLN C N   1 
ATOM   2569 C CA  . GLN C 1 35  ? -16.68246 -47.18528 -24.46503 1.000 21.20903 ? 35  GLN C CA  1 
ATOM   2570 C C   . GLN C 1 35  ? -17.11275 -46.61848 -23.11650 1.000 23.03486 ? 35  GLN C C   1 
ATOM   2571 O O   . GLN C 1 35  ? -17.33058 -45.40728 -22.98577 1.000 17.23270 ? 35  GLN C O   1 
ATOM   2572 C CB  . GLN C 1 35  ? -15.18150 -46.97079 -24.63350 1.000 20.87907 ? 35  GLN C CB  1 
ATOM   2573 C CG  . GLN C 1 35  ? -14.61004 -47.72226 -25.80289 1.000 26.05165 ? 35  GLN C CG  1 
ATOM   2574 C CD  . GLN C 1 35  ? -14.36997 -46.74746 -26.93256 1.000 31.71345 ? 35  GLN C CD  1 
ATOM   2575 O OE1 . GLN C 1 35  ? -15.29349 -46.03613 -27.32955 1.000 31.89295 ? 35  GLN C OE1 1 
ATOM   2576 N NE2 . GLN C 1 35  ? -13.15762 -46.73925 -27.49637 1.000 27.16219 ? 35  GLN C NE2 1 
ATOM   2577 N N   . HIS C 1 36  ? -17.23300 -47.50213 -22.11435 1.000 21.09628 ? 36  HIS C N   1 
ATOM   2578 C CA  . HIS C 1 36  ? -17.33748 -47.14492 -20.69886 1.000 23.74203 ? 36  HIS C CA  1 
ATOM   2579 C C   . HIS C 1 36  ? -16.64394 -45.84596 -20.33959 1.000 19.42306 ? 36  HIS C C   1 
ATOM   2580 O O   . HIS C 1 36  ? -17.25948 -44.93451 -19.78226 1.000 16.06596 ? 36  HIS C O   1 
ATOM   2581 C CB  . HIS C 1 36  ? -16.68266 -48.19937 -19.80693 1.000 25.88256 ? 36  HIS C CB  1 
ATOM   2582 C CG  . HIS C 1 36  ? -17.34966 -49.53114 -19.78690 1.000 37.69689 ? 36  HIS C CG  1 
ATOM   2583 N ND1 . HIS C 1 36  ? -18.70106 -49.69384 -19.57324 1.000 35.59393 ? 36  HIS C ND1 1 
ATOM   2584 C CD2 . HIS C 1 36  ? -16.84100 -50.77370 -19.96489 1.000 42.93677 ? 36  HIS C CD2 1 
ATOM   2585 C CE1 . HIS C 1 36  ? -18.97969 -50.98635 -19.56140 1.000 38.72710 ? 36  HIS C CE1 1 
ATOM   2586 N NE2 . HIS C 1 36  ? -17.87821 -51.66007 -19.83201 1.000 41.44074 ? 36  HIS C NE2 1 
ATOM   2587 N N   . PHE C 1 37  ? -15.33239 -45.78818 -20.59723 1.000 18.33603 ? 37  PHE C N   1 
ATOM   2588 C CA  . PHE C 1 37  ? -14.53635 -44.71880 -20.02695 1.000 19.63285 ? 37  PHE C CA  1 
ATOM   2589 C C   . PHE C 1 37  ? -14.80450 -43.37289 -20.67752 1.000 19.22550 ? 37  PHE C C   1 
ATOM   2590 O O   . PHE C 1 37  ? -14.29230 -42.36845 -20.18753 1.000 16.05252 ? 37  PHE C O   1 
ATOM   2591 C CB  . PHE C 1 37  ? -13.03672 -45.03561 -20.10651 1.000 19.96600 ? 37  PHE C CB  1 
ATOM   2592 C CG  . PHE C 1 37  ? -12.58671 -45.54548 -21.44052 1.000 19.14441 ? 37  PHE C CG  1 
ATOM   2593 C CD1 . PHE C 1 37  ? -12.38063 -44.67229 -22.49612 1.000 20.29997 ? 37  PHE C CD1 1 
ATOM   2594 C CD2 . PHE C 1 37  ? -12.29651 -46.88936 -21.61656 1.000 22.50361 ? 37  PHE C CD2 1 
ATOM   2595 C CE1 . PHE C 1 37  ? -11.94876 -45.13382 -23.72343 1.000 23.76486 ? 37  PHE C CE1 1 
ATOM   2596 C CE2 . PHE C 1 37  ? -11.85568 -47.36233 -22.83788 1.000 22.93442 ? 37  PHE C CE2 1 
ATOM   2597 C CZ  . PHE C 1 37  ? -11.68296 -46.48484 -23.89563 1.000 22.90461 ? 37  PHE C CZ  1 
ATOM   2598 N N   . LEU C 1 38  ? -15.59851 -43.32413 -21.74090 1.000 15.18767 ? 38  LEU C N   1 
ATOM   2599 C CA  . LEU C 1 38  ? -15.93856 -42.05443 -22.36413 1.000 14.84304 ? 38  LEU C CA  1 
ATOM   2600 C C   . LEU C 1 38  ? -17.20581 -41.43290 -21.78128 1.000 13.31523 ? 38  LEU C C   1 
ATOM   2601 O O   . LEU C 1 38  ? -17.58779 -40.34049 -22.20591 1.000 15.85302 ? 38  LEU C O   1 
ATOM   2602 C CB  . LEU C 1 38  ? -16.08588 -42.25012 -23.87979 1.000 18.45017 ? 38  LEU C CB  1 
ATOM   2603 C CG  . LEU C 1 38  ? -14.78058 -42.57353 -24.62360 1.000 15.47271 ? 38  LEU C CG  1 
ATOM   2604 C CD1 . LEU C 1 38  ? -15.01677 -42.70126 -26.11114 1.000 22.20339 ? 38  LEU C CD1 1 
ATOM   2605 C CD2 . LEU C 1 38  ? -13.68582 -41.53694 -24.32961 1.000 17.73241 ? 38  LEU C CD2 1 
ATOM   2606 N N   . ALA C 1 39  ? -17.85603 -42.08779 -20.81340 1.000 11.66977 ? 39  ALA C N   1 
ATOM   2607 C CA  . ALA C 1 39  ? -19.11962 -41.60993 -20.25369 1.000 13.27065 ? 39  ALA C CA  1 
ATOM   2608 C C   . ALA C 1 39  ? -18.85582 -41.07412 -18.85565 1.000 14.22475 ? 39  ALA C C   1 
ATOM   2609 O O   . ALA C 1 39  ? -18.39525 -41.81716 -17.98283 1.000 15.53928 ? 39  ALA C O   1 
ATOM   2610 C CB  . ALA C 1 39  ? -20.17458 -42.72069 -20.21582 1.000 13.12629 ? 39  ALA C CB  1 
ATOM   2611 N N   . GLN C 1 40  ? -19.11172 -39.77772 -18.65553 1.000 10.91154 ? 40  GLN C N   1 
ATOM   2612 C CA  . GLN C 1 40  ? -18.97525 -39.15678 -17.34837 1.000 13.82378 ? 40  GLN C CA  1 
ATOM   2613 C C   . GLN C 1 40  ? -20.36119 -38.99672 -16.74925 1.000 13.99204 ? 40  GLN C C   1 
ATOM   2614 O O   . GLN C 1 40  ? -21.31939 -38.66636 -17.46410 1.000 12.87528 ? 40  GLN C O   1 
ATOM   2615 C CB  . GLN C 1 40  ? -18.27677 -37.79214 -17.43199 1.000 10.59760 ? 40  GLN C CB  1 
ATOM   2616 C CG  . GLN C 1 40  ? -18.25821 -37.03984 -16.08590 1.000 13.12061 ? 40  GLN C CG  1 
ATOM   2617 C CD  . GLN C 1 40  ? -17.49473 -35.70896 -16.10545 1.000 15.96589 ? 40  GLN C CD  1 
ATOM   2618 O OE1 . GLN C 1 40  ? -17.72510 -34.85563 -15.24469 1.000 18.36222 ? 40  GLN C OE1 1 
ATOM   2619 N NE2 . GLN C 1 40  ? -16.57142 -35.54001 -17.05586 1.000 11.74134 ? 40  GLN C NE2 1 
ATOM   2620 N N   . VAL C 1 41  ? -20.47302 -39.28427 -15.45106 1.000 11.88125 ? 41  VAL C N   1 
ATOM   2621 C CA  . VAL C 1 41  ? -21.67803 -39.00604 -14.67135 1.000 13.42159 ? 41  VAL C CA  1 
ATOM   2622 C C   . VAL C 1 41  ? -21.26130 -38.06518 -13.54628 1.000 15.03801 ? 41  VAL C C   1 
ATOM   2623 O O   . VAL C 1 41  ? -20.34789 -38.37507 -12.76904 1.000 15.87386 ? 41  VAL C O   1 
ATOM   2624 C CB  . VAL C 1 41  ? -22.34530 -40.27723 -14.11386 1.000 12.23184 ? 41  VAL C CB  1 
ATOM   2625 C CG1 . VAL C 1 41  ? -23.55046 -39.90272 -13.22971 1.000 11.55421 ? 41  VAL C CG1 1 
ATOM   2626 C CG2 . VAL C 1 41  ? -22.79980 -41.21955 -15.23497 1.000 12.78286 ? 41  VAL C CG2 1 
ATOM   2627 N N   . ASN C 1 42  ? -21.91146 -36.90979 -13.48110 1.000 14.45437 ? 42  ASN C N   1 
ATOM   2628 C CA  . ASN C 1 42  ? -21.47404 -35.77809 -12.66584 1.000 13.10345 ? 42  ASN C CA  1 
ATOM   2629 C C   . ASN C 1 42  ? -22.64146 -35.38765 -11.76326 1.000 16.39283 ? 42  ASN C C   1 
ATOM   2630 O O   . ASN C 1 42  ? -23.59030 -34.73657 -12.20586 1.000 13.54519 ? 42  ASN C O   1 
ATOM   2631 C CB  . ASN C 1 42  ? -21.02513 -34.61763 -13.55667 1.000 15.56629 ? 42  ASN C CB  1 
ATOM   2632 C CG  . ASN C 1 42  ? -20.22373 -33.57038 -12.79399 1.000 15.92663 ? 42  ASN C CG  1 
ATOM   2633 O OD1 . ASN C 1 42  ? -20.63202 -33.14187 -11.73216 1.000 16.24679 ? 42  ASN C OD1 1 
ATOM   2634 N ND2 . ASN C 1 42  ? -19.07840 -33.17718 -13.32625 1.000 16.38145 ? 42  ASN C ND2 1 
ATOM   2635 N N   . PHE C 1 43  ? -22.58629 -35.81274 -10.50466 1.000 15.45726 ? 43  PHE C N   1 
ATOM   2636 C CA  . PHE C 1 43  ? -23.66941 -35.54939 -9.56502  1.000 12.55825 ? 43  PHE C CA  1 
ATOM   2637 C C   . PHE C 1 43  ? -23.57563 -34.12465 -9.03144  1.000 15.50826 ? 43  PHE C C   1 
ATOM   2638 O O   . PHE C 1 43  ? -22.52564 -33.70320 -8.54085  1.000 13.51587 ? 43  PHE C O   1 
ATOM   2639 C CB  . PHE C 1 43  ? -23.61752 -36.55194 -8.40885  1.000 12.82182 ? 43  PHE C CB  1 
ATOM   2640 C CG  . PHE C 1 43  ? -24.06752 -37.93705 -8.79294  1.000 14.65714 ? 43  PHE C CG  1 
ATOM   2641 C CD1 . PHE C 1 43  ? -25.42147 -38.22713 -8.92556  1.000 15.01840 ? 43  PHE C CD1 1 
ATOM   2642 C CD2 . PHE C 1 43  ? -23.14361 -38.94448 -9.03430  1.000 14.98942 ? 43  PHE C CD2 1 
ATOM   2643 C CE1 . PHE C 1 43  ? -25.84614 -39.50427 -9.27268  1.000 16.88154 ? 43  PHE C CE1 1 
ATOM   2644 C CE2 . PHE C 1 43  ? -23.56106 -40.21639 -9.38946  1.000 17.38866 ? 43  PHE C CE2 1 
ATOM   2645 C CZ  . PHE C 1 43  ? -24.90316 -40.50050 -9.51708  1.000 15.07388 ? 43  PHE C CZ  1 
ATOM   2646 N N   . GLN C 1 44  ? -24.68193 -33.39623 -9.11417  1.000 10.64255 ? 44  GLN C N   1 
ATOM   2647 C CA  . GLN C 1 44  ? -24.79848 -32.03757 -8.60012  1.000 10.86463 ? 44  GLN C CA  1 
ATOM   2648 C C   . GLN C 1 44  ? -25.84650 -32.07033 -7.49324  1.000 11.09454 ? 44  GLN C C   1 
ATOM   2649 O O   . GLN C 1 44  ? -27.04444 -32.09728 -7.78042  1.000 13.52248 ? 44  GLN C O   1 
ATOM   2650 C CB  . GLN C 1 44  ? -25.18860 -31.06619 -9.69789  1.000 14.24245 ? 44  GLN C CB  1 
ATOM   2651 C CG  . GLN C 1 44  ? -24.14978 -30.99803 -10.81080 1.000 15.63475 ? 44  GLN C CG  1 
ATOM   2652 C CD  . GLN C 1 44  ? -22.94210 -30.21146 -10.38552 1.000 16.11553 ? 44  GLN C CD  1 
ATOM   2653 O OE1 . GLN C 1 44  ? -23.07843 -29.08791 -9.90742  1.000 16.34645 ? 44  GLN C OE1 1 
ATOM   2654 N NE2 . GLN C 1 44  ? -21.74228 -30.78521 -10.55997 1.000 12.07094 ? 44  GLN C NE2 1 
ATOM   2655 N N   . GLU C 1 45  ? -25.39358 -32.06893 -6.23549  1.000 12.66604 ? 45  GLU C N   1 
ATOM   2656 C CA  . GLU C 1 45  ? -26.28915 -32.07171 -5.08367  1.000 12.48147 ? 45  GLU C CA  1 
ATOM   2657 C C   . GLU C 1 45  ? -26.57456 -30.64991 -4.61928  1.000 15.72694 ? 45  GLU C C   1 
ATOM   2658 O O   . GLU C 1 45  ? -25.67386 -29.80322 -4.56929  1.000 14.97407 ? 45  GLU C O   1 
ATOM   2659 C CB  . GLU C 1 45  ? -25.67894 -32.85327 -3.92134  1.000 17.25787 ? 45  GLU C CB  1 
ATOM   2660 C CG  . GLU C 1 45  ? -25.58834 -34.32678 -4.18217  1.000 19.51151 ? 45  GLU C CG  1 
ATOM   2661 C CD  . GLU C 1 45  ? -24.77004 -35.04037 -3.13677  1.000 23.59784 ? 45  GLU C CD  1 
ATOM   2662 O OE1 . GLU C 1 45  ? -23.56011 -34.72470 -2.98542  1.000 24.04646 ? 45  GLU C OE1 1 
ATOM   2663 O OE2 . GLU C 1 45  ? -25.33800 -35.93317 -2.48126  1.000 25.68966 ? 45  GLU C OE2 1 
ATOM   2664 N N   . GLN C 1 46  ? -27.82642 -30.40201 -4.26859  1.000 13.42187 ? 46  GLN C N   1 
ATOM   2665 C CA  . GLN C 1 46  ? -28.27986 -29.16202 -3.66009  1.000 12.09316 ? 46  GLN C CA  1 
ATOM   2666 C C   . GLN C 1 46  ? -29.18289 -29.52305 -2.49351  1.000 18.79691 ? 46  GLN C C   1 
ATOM   2667 O O   . GLN C 1 46  ? -29.77795 -30.60626 -2.47471  1.000 15.17651 ? 46  GLN C O   1 
ATOM   2668 C CB  . GLN C 1 46  ? -29.06391 -28.30553 -4.66517  1.000 13.04933 ? 46  GLN C CB  1 
ATOM   2669 C CG  . GLN C 1 46  ? -28.20227 -27.71824 -5.77887  1.000 15.09998 ? 46  GLN C CG  1 
ATOM   2670 C CD  . GLN C 1 46  ? -27.41054 -26.53867 -5.28838  1.000 16.99879 ? 46  GLN C CD  1 
ATOM   2671 O OE1 . GLN C 1 46  ? -27.94481 -25.67307 -4.59635  1.000 14.69519 ? 46  GLN C OE1 1 
ATOM   2672 N NE2 . GLN C 1 46  ? -26.12463 -26.50221 -5.62274  1.000 16.72289 ? 46  GLN C NE2 1 
ATOM   2673 N N   . PRO C 1 47  ? -29.32081 -28.63540 -1.51349  1.000 17.11962 ? 47  PRO C N   1 
ATOM   2674 C CA  . PRO C 1 47  ? -30.27127 -28.89629 -0.42089  1.000 18.50527 ? 47  PRO C CA  1 
ATOM   2675 C C   . PRO C 1 47  ? -31.67687 -29.16978 -0.94432  1.000 21.15018 ? 47  PRO C C   1 
ATOM   2676 O O   . PRO C 1 47  ? -32.12773 -28.57234 -1.92133  1.000 17.85095 ? 47  PRO C O   1 
ATOM   2677 C CB  . PRO C 1 47  ? -30.21779 -27.60883 0.41068   1.000 22.53271 ? 47  PRO C CB  1 
ATOM   2678 C CG  . PRO C 1 47  ? -29.62163 -26.56986 -0.49453  1.000 22.80948 ? 47  PRO C CG  1 
ATOM   2679 C CD  . PRO C 1 47  ? -28.64587 -27.33486 -1.35817  1.000 16.66198 ? 47  PRO C CD  1 
ATOM   2680 N N   . ALA C 1 48  ? -32.36642 -30.10446 -0.29517  1.000 20.48966 ? 48  ALA C N   1 
ATOM   2681 C CA  . ALA C 1 48  ? -33.78675 -30.28896 -0.55139  1.000 18.37866 ? 48  ALA C CA  1 
ATOM   2682 C C   . ALA C 1 48  ? -34.52016 -28.97196 -0.34985  1.000 17.84718 ? 48  ALA C C   1 
ATOM   2683 O O   . ALA C 1 48  ? -34.16225 -28.17342 0.52294   1.000 21.55297 ? 48  ALA C O   1 
ATOM   2684 C CB  . ALA C 1 48  ? -34.36261 -31.35708 0.38025   1.000 19.26749 ? 48  ALA C CB  1 
ATOM   2685 N N   . GLY C 1 49  ? -35.54543 -28.74942 -1.16690  1.000 18.76694 ? 49  GLY C N   1 
ATOM   2686 C CA  . GLY C 1 49  ? -36.28104 -27.50547 -1.19329  1.000 17.72697 ? 49  GLY C CA  1 
ATOM   2687 C C   . GLY C 1 49  ? -35.84760 -26.52963 -2.26989  1.000 17.96570 ? 49  GLY C C   1 
ATOM   2688 O O   . GLY C 1 49  ? -36.48944 -25.48676 -2.42999  1.000 20.27194 ? 49  GLY C O   1 
ATOM   2689 N N   . ASN C 1 50  ? -34.78625 -26.83528 -3.01207  1.000 16.55194 ? 50  ASN C N   1 
ATOM   2690 C CA  . ASN C 1 50  ? -34.33751 -25.98088 -4.10804  1.000 16.59977 ? 50  ASN C CA  1 
ATOM   2691 C C   . ASN C 1 50  ? -35.01292 -26.31620 -5.43347  1.000 16.15489 ? 50  ASN C C   1 
ATOM   2692 O O   . ASN C 1 50  ? -34.76396 -25.63276 -6.43457  1.000 14.72043 ? 50  ASN C O   1 
ATOM   2693 C CB  . ASN C 1 50  ? -32.81535 -26.07952 -4.25029  1.000 16.25893 ? 50  ASN C CB  1 
ATOM   2694 C CG  . ASN C 1 50  ? -32.08671 -25.12390 -3.31395  1.000 18.90263 ? 50  ASN C CG  1 
ATOM   2695 O OD1 . ASN C 1 50  ? -32.68119 -24.60596 -2.36582  1.000 21.98230 ? 50  ASN C OD1 1 
ATOM   2696 N ND2 . ASN C 1 50  ? -30.79982 -24.88922 -3.56768  1.000 15.52490 ? 50  ASN C ND2 1 
ATOM   2697 N N   . VAL C 1 51  ? -35.86233 -27.34286 -5.46757  1.000 16.35535 ? 51  VAL C N   1 
ATOM   2698 C CA  . VAL C 1 51  ? -36.59096 -27.73098 -6.67555  1.000 17.68773 ? 51  VAL C CA  1 
ATOM   2699 C C   . VAL C 1 51  ? -38.05639 -27.35582 -6.52348  1.000 16.75301 ? 51  VAL C C   1 
ATOM   2700 O O   . VAL C 1 51  ? -38.68260 -27.66699 -5.49996  1.000 17.87123 ? 51  VAL C O   1 
ATOM   2701 C CB  . VAL C 1 51  ? -36.46390 -29.23694 -6.96207  1.000 15.10598 ? 51  VAL C CB  1 
ATOM   2702 C CG1 . VAL C 1 51  ? -37.29156 -29.59637 -8.19036  1.000 18.14187 ? 51  VAL C CG1 1 
ATOM   2703 C CG2 . VAL C 1 51  ? -35.01051 -29.60486 -7.14706  1.000 16.59931 ? 51  VAL C CG2 1 
ATOM   2704 N N   . PHE C 1 52  ? -38.60928 -26.71828 -7.55235  1.000 13.11167 ? 52  PHE C N   1 
ATOM   2705 C CA  . PHE C 1 52  ? -40.01715 -26.35079 -7.58882  1.000 14.63964 ? 52  PHE C CA  1 
ATOM   2706 C C   . PHE C 1 52  ? -40.64335 -26.92718 -8.84880  1.000 17.13778 ? 52  PHE C C   1 
ATOM   2707 O O   . PHE C 1 52  ? -40.04501 -26.86096 -9.92810  1.000 15.38886 ? 52  PHE C O   1 
ATOM   2708 C CB  . PHE C 1 52  ? -40.18399 -24.83126 -7.57218  1.000 14.99113 ? 52  PHE C CB  1 
ATOM   2709 C CG  . PHE C 1 52  ? -39.72098 -24.19092 -6.29840  1.000 20.70714 ? 52  PHE C CG  1 
ATOM   2710 C CD1 . PHE C 1 52  ? -38.36859 -24.03831 -6.03889  1.000 16.78301 ? 52  PHE C CD1 1 
ATOM   2711 C CD2 . PHE C 1 52  ? -40.64121 -23.73411 -5.35655  1.000 19.35455 ? 52  PHE C CD2 1 
ATOM   2712 C CE1 . PHE C 1 52  ? -37.93804 -23.45864 -4.86878  1.000 19.68046 ? 52  PHE C CE1 1 
ATOM   2713 C CE2 . PHE C 1 52  ? -40.20957 -23.14698 -4.18152  1.000 21.78977 ? 52  PHE C CE2 1 
ATOM   2714 C CZ  . PHE C 1 52  ? -38.85647 -23.00657 -3.93864  1.000 18.84755 ? 52  PHE C CZ  1 
ATOM   2715 N N   . LEU C 1 53  ? -41.83373 -27.51823 -8.70947  1.000 14.75030 ? 53  LEU C N   1 
ATOM   2716 C CA  . LEU C 1 53  ? -42.61807 -28.00187 -9.84286  1.000 16.68816 ? 53  LEU C CA  1 
ATOM   2717 C C   . LEU C 1 53  ? -43.94646 -27.26803 -9.81305  1.000 17.47950 ? 53  LEU C C   1 
ATOM   2718 O O   . LEU C 1 53  ? -44.66226 -27.33469 -8.80910  1.000 20.75753 ? 53  LEU C O   1 
ATOM   2719 C CB  . LEU C 1 53  ? -42.84603 -29.51393 -9.77105  1.000 16.12531 ? 53  LEU C CB  1 
ATOM   2720 C CG  . LEU C 1 53  ? -41.60133 -30.39346 -9.70654  1.000 16.79810 ? 53  LEU C CG  1 
ATOM   2721 C CD1 . LEU C 1 53  ? -41.92956 -31.87304 -9.62981  1.000 14.92186 ? 53  LEU C CD1 1 
ATOM   2722 C CD2 . LEU C 1 53  ? -40.65061 -30.09400 -10.86402 1.000 17.20157 ? 53  LEU C CD2 1 
ATOM   2723 N N   . GLY C 1 54  ? -44.26305 -26.55326 -10.89066 1.000 15.58926 ? 54  GLY C N   1 
ATOM   2724 C CA  . GLY C 1 54  ? -45.46015 -25.72603 -10.89956 1.000 16.65375 ? 54  GLY C CA  1 
ATOM   2725 C C   . GLY C 1 54  ? -45.50989 -24.70041 -9.79222  1.000 23.74031 ? 54  GLY C C   1 
ATOM   2726 O O   . GLY C 1 54  ? -46.60156 -24.29382 -9.38358  1.000 22.35630 ? 54  GLY C O   1 
ATOM   2727 N N   . GLY C 1 55  ? -44.35196 -24.26567 -9.29221  1.000 18.33044 ? 55  GLY C N   1 
ATOM   2728 C CA  . GLY C 1 55  ? -44.29650 -23.34337 -8.17359  1.000 17.08444 ? 55  GLY C CA  1 
ATOM   2729 C C   . GLY C 1 55  ? -44.36376 -23.98605 -6.80502  1.000 18.42908 ? 55  GLY C C   1 
ATOM   2730 O O   . GLY C 1 55  ? -44.30657 -23.26348 -5.79966  1.000 22.18166 ? 55  GLY C O   1 
ATOM   2731 N N   . VAL C 1 56  ? -44.47431 -25.31345 -6.73411  1.000 18.84223 ? 56  VAL C N   1 
ATOM   2732 C CA  . VAL C 1 56  ? -44.54874 -26.05113 -5.47532  1.000 21.00806 ? 56  VAL C CA  1 
ATOM   2733 C C   . VAL C 1 56  ? -43.16477 -26.57193 -5.10875  1.000 18.49163 ? 56  VAL C C   1 
ATOM   2734 O O   . VAL C 1 56  ? -42.55537 -27.34299 -5.86623  1.000 19.07139 ? 56  VAL C O   1 
ATOM   2735 C CB  . VAL C 1 56  ? -45.55235 -27.21304 -5.56702  1.000 20.48457 ? 56  VAL C CB  1 
ATOM   2736 C CG1 . VAL C 1 56  ? -45.54739 -28.03008 -4.27884  1.000 20.24462 ? 56  VAL C CG1 1 
ATOM   2737 C CG2 . VAL C 1 56  ? -46.94074 -26.70045 -5.90149  1.000 18.48809 ? 56  VAL C CG2 1 
ATOM   2738 N N   . GLN C 1 57  ? -42.69055 -26.20084 -3.91980  1.000 18.03790 ? 57  GLN C N   1 
ATOM   2739 C CA  . GLN C 1 57  ? -41.42463 -26.71723 -3.41542  1.000 19.69130 ? 57  GLN C CA  1 
ATOM   2740 C C   . GLN C 1 57  ? -41.50339 -28.22956 -3.24908  1.000 25.34709 ? 57  GLN C C   1 
ATOM   2741 O O   . GLN C 1 57  ? -42.49796 -28.76440 -2.74430  1.000 22.03360 ? 57  GLN C O   1 
ATOM   2742 C CB  . GLN C 1 57  ? -41.08343 -26.09049 -2.06481  1.000 19.80926 ? 57  GLN C CB  1 
ATOM   2743 C CG  . GLN C 1 57  ? -39.71212 -26.50269 -1.53450  1.000 21.97616 ? 57  GLN C CG  1 
ATOM   2744 C CD  . GLN C 1 57  ? -39.40581 -25.87267 -0.18806  1.000 31.99769 ? 57  GLN C CD  1 
ATOM   2745 O OE1 . GLN C 1 57  ? -38.42127 -25.16347 -0.02198  1.000 34.71592 ? 57  GLN C OE1 1 
ATOM   2746 N NE2 . GLN C 1 57  ? -40.21079 -26.22202 0.81015   1.000 29.02660 ? 57  GLN C NE2 1 
ATOM   2747 N N   . GLN C 1 58  ? -40.43840 -28.91733 -3.65692  1.000 16.80285 ? 58  GLN C N   1 
ATOM   2748 C CA  . GLN C 1 58  ? -40.35581 -30.36455 -3.57543  1.000 17.04371 ? 58  GLN C CA  1 
ATOM   2749 C C   . GLN C 1 58  ? -39.49573 -30.77780 -2.39311  1.000 18.21761 ? 58  GLN C C   1 
ATOM   2750 O O   . GLN C 1 58  ? -38.68711 -30.00037 -1.88325  1.000 20.89638 ? 58  GLN C O   1 
ATOM   2751 C CB  . GLN C 1 58  ? -39.76010 -30.95875 -4.86263  1.000 18.40160 ? 58  GLN C CB  1 
ATOM   2752 C CG  . GLN C 1 58  ? -40.51232 -30.56256 -6.12925  1.000 18.26004 ? 58  GLN C CG  1 
ATOM   2753 C CD  . GLN C 1 58  ? -41.93609 -31.08654 -6.12630  1.000 24.13742 ? 58  GLN C CD  1 
ATOM   2754 O OE1 . GLN C 1 58  ? -42.14661 -32.29067 -6.15063  1.000 23.52675 ? 58  GLN C OE1 1 
ATOM   2755 N NE2 . GLN C 1 58  ? -42.91445 -30.18440 -6.14193  1.000 17.32121 ? 58  GLN C NE2 1 
ATOM   2756 N N   . GLY C 1 59  ? -39.67099 -32.03183 -1.97601  1.000 21.96025 ? 59  GLY C N   1 
ATOM   2757 C CA  . GLY C 1 59  ? -38.75097 -32.68237 -1.06401  1.000 22.09523 ? 59  GLY C CA  1 
ATOM   2758 C C   . GLY C 1 59  ? -37.51960 -33.17906 -1.79387  1.000 27.67479 ? 59  GLY C C   1 
ATOM   2759 O O   . GLY C 1 59  ? -37.14845 -32.66859 -2.85655  1.000 28.09925 ? 59  GLY C O   1 
ATOM   2760 N N   . GLY C 1 60  ? -36.88748 -34.20001 -1.24048  1.000 25.25486 ? 60  GLY C N   1 
ATOM   2761 C CA  . GLY C 1 60  ? -35.64435 -34.68964 -1.80511  1.000 26.63469 ? 60  GLY C CA  1 
ATOM   2762 C C   . GLY C 1 60  ? -35.74815 -35.75937 -2.87650  1.000 23.48555 ? 60  GLY C C   1 
ATOM   2763 O O   . GLY C 1 60  ? -34.71443 -36.32900 -3.23593  1.000 20.59277 ? 60  GLY C O   1 
ATOM   2764 N N   . ASP C 1 61  ? -36.93994 -36.02678 -3.42298  1.000 20.98970 ? 61  ASP C N   1 
ATOM   2765 C CA  . ASP C 1 61  ? -37.17792 -37.16347 -4.31679  1.000 26.04625 ? 61  ASP C CA  1 
ATOM   2766 C C   . ASP C 1 61  ? -37.22238 -36.82320 -5.80217  1.000 27.82178 ? 61  ASP C C   1 
ATOM   2767 O O   . ASP C 1 61  ? -37.73779 -37.62923 -6.57457  1.000 37.64732 ? 61  ASP C O   1 
ATOM   2768 C CB  . ASP C 1 61  ? -38.48908 -37.88055 -3.98084  1.000 30.96725 ? 61  ASP C CB  1 
ATOM   2769 C CG  . ASP C 1 61  ? -38.29218 -39.12752 -3.17912  1.000 34.46756 ? 61  ASP C CG  1 
ATOM   2770 O OD1 . ASP C 1 61  ? -37.39309 -39.15911 -2.31826  1.000 41.17040 ? 61  ASP C OD1 1 
ATOM   2771 O OD2 . ASP C 1 61  ? -39.02576 -40.10982 -3.46605  1.000 40.08180 ? 61  ASP C OD2 1 
ATOM   2772 N N   . THR C 1 62  ? -36.72785 -35.67683 -6.23335  1.000 26.51660 ? 62  THR C N   1 
ATOM   2773 C CA  . THR C 1 62  ? -36.70547 -35.37742 -7.65996  1.000 20.52118 ? 62  THR C CA  1 
ATOM   2774 C C   . THR C 1 62  ? -35.31441 -35.66863 -8.20810  1.000 19.41678 ? 62  THR C C   1 
ATOM   2775 O O   . THR C 1 62  ? -34.31295 -35.44985 -7.52337  1.000 21.63054 ? 62  THR C O   1 
ATOM   2776 C CB  . THR C 1 62  ? -37.08145 -33.91935 -7.94026  1.000 25.61390 ? 62  THR C CB  1 
ATOM   2777 O OG1 . THR C 1 62  ? -38.20763 -33.54765 -7.13660  1.000 32.53607 ? 62  THR C OG1 1 
ATOM   2778 C CG2 . THR C 1 62  ? -37.46020 -33.74855 -9.40761  1.000 30.69143 ? 62  THR C CG2 1 
ATOM   2779 N N   . ILE C 1 63  ? -35.24464 -36.17852 -9.43357  1.000 16.37743 ? 63  ILE C N   1 
ATOM   2780 C CA  . ILE C 1 63  ? -33.95763 -36.31291 -10.10470 1.000 14.51823 ? 63  ILE C CA  1 
ATOM   2781 C C   . ILE C 1 63  ? -34.11090 -35.77725 -11.52433 1.000 12.52921 ? 63  ILE C C   1 
ATOM   2782 O O   . ILE C 1 63  ? -35.08371 -36.09155 -12.21927 1.000 15.24457 ? 63  ILE C O   1 
ATOM   2783 C CB  . ILE C 1 63  ? -33.43916 -37.76912 -10.08216 1.000 14.51406 ? 63  ILE C CB  1 
ATOM   2784 C CG1 . ILE C 1 63  ? -32.30008 -37.97095 -11.09167 1.000 15.72676 ? 63  ILE C CG1 1 
ATOM   2785 C CG2 . ILE C 1 63  ? -34.56526 -38.75470 -10.35204 1.000 28.49649 ? 63  ILE C CG2 1 
ATOM   2786 C CD1 . ILE C 1 63  ? -31.44368 -39.15319 -10.76647 1.000 32.55355 ? 63  ILE C CD1 1 
ATOM   2787 N N   . PHE C 1 64  ? -33.17603 -34.93184 -11.93974 1.000 15.03418 ? 64  PHE C N   1 
ATOM   2788 C CA  . PHE C 1 64  ? -33.14657 -34.40840 -13.29758 1.000 12.63002 ? 64  PHE C CA  1 
ATOM   2789 C C   . PHE C 1 64  ? -31.81275 -34.80957 -13.90986 1.000 12.14968 ? 64  PHE C C   1 
ATOM   2790 O O   . PHE C 1 64  ? -30.76182 -34.47583 -13.35942 1.000 12.91232 ? 64  PHE C O   1 
ATOM   2791 C CB  . PHE C 1 64  ? -33.31606 -32.88286 -13.30371 1.000 13.46794 ? 64  PHE C CB  1 
ATOM   2792 C CG  . PHE C 1 64  ? -33.06836 -32.24836 -14.66137 1.000 12.33905 ? 64  PHE C CG  1 
ATOM   2793 C CD1 . PHE C 1 64  ? -33.56410 -32.84051 -15.81811 1.000 11.30529 ? 64  PHE C CD1 1 
ATOM   2794 C CD2 . PHE C 1 64  ? -32.32189 -31.08741 -14.77644 1.000 15.12113 ? 64  PHE C CD2 1 
ATOM   2795 C CE1 . PHE C 1 64  ? -33.32258 -32.27373 -17.08197 1.000 11.25908 ? 64  PHE C CE1 1 
ATOM   2796 C CE2 . PHE C 1 64  ? -32.08530 -30.50513 -16.02444 1.000 12.66878 ? 64  PHE C CE2 1 
ATOM   2797 C CZ  . PHE C 1 64  ? -32.59417 -31.11058 -17.18687 1.000 11.02164 ? 64  PHE C CZ  1 
ATOM   2798 N N   . VAL C 1 65  ? -31.85462 -35.54848 -15.01904 1.000 9.87686  ? 65  VAL C N   1 
ATOM   2799 C CA  . VAL C 1 65  ? -30.65558 -35.97773 -15.74051 1.000 7.64106  ? 65  VAL C CA  1 
ATOM   2800 C C   . VAL C 1 65  ? -30.54888 -35.13159 -17.00179 1.000 10.56588 ? 65  VAL C C   1 
ATOM   2801 O O   . VAL C 1 65  ? -31.42350 -35.20066 -17.87148 1.000 11.52284 ? 65  VAL C O   1 
ATOM   2802 C CB  . VAL C 1 65  ? -30.69658 -37.47832 -16.08267 1.000 13.67618 ? 65  VAL C CB  1 
ATOM   2803 C CG1 . VAL C 1 65  ? -29.43716 -37.88554 -16.88867 1.000 14.69766 ? 65  VAL C CG1 1 
ATOM   2804 C CG2 . VAL C 1 65  ? -30.76201 -38.31817 -14.81043 1.000 14.12070 ? 65  VAL C CG2 1 
ATOM   2805 N N   . HIS C 1 66  ? -29.46370 -34.34557 -17.11474 1.000 11.75759 ? 66  HIS C N   1 
ATOM   2806 C CA  . HIS C 1 66  ? -29.17722 -33.55927 -18.31630 1.000 12.65990 ? 66  HIS C CA  1 
ATOM   2807 C C   . HIS C 1 66  ? -28.00990 -34.23406 -19.02573 1.000 11.95843 ? 66  HIS C C   1 
ATOM   2808 O O   . HIS C 1 66  ? -26.86108 -34.06147 -18.62393 1.000 12.59269 ? 66  HIS C O   1 
ATOM   2809 C CB  . HIS C 1 66  ? -28.84913 -32.10723 -17.96088 1.000 11.68804 ? 66  HIS C CB  1 
ATOM   2810 C CG  . HIS C 1 66  ? -28.80024 -31.18113 -19.14230 1.000 13.95099 ? 66  HIS C CG  1 
ATOM   2811 N ND1 . HIS C 1 66  ? -28.31625 -29.89082 -19.05282 1.000 11.96120 ? 66  HIS C ND1 1 
ATOM   2812 C CD2 . HIS C 1 66  ? -29.18506 -31.34975 -20.43049 1.000 12.00081 ? 66  HIS C CD2 1 
ATOM   2813 C CE1 . HIS C 1 66  ? -28.40593 -29.30321 -20.23293 1.000 14.96494 ? 66  HIS C CE1 1 
ATOM   2814 N NE2 . HIS C 1 66  ? -28.93620 -30.16403 -21.08642 1.000 15.88438 ? 66  HIS C NE2 1 
ATOM   2815 N N   . GLY C 1 67  ? -28.30724 -35.01680 -20.06475 1.000 11.63087 ? 67  GLY C N   1 
ATOM   2816 C CA  . GLY C 1 67  ? -27.26995 -35.70810 -20.81950 1.000 10.98403 ? 67  GLY C CA  1 
ATOM   2817 C C   . GLY C 1 67  ? -26.79536 -34.84121 -21.97326 1.000 10.99685 ? 67  GLY C C   1 
ATOM   2818 O O   . GLY C 1 67  ? -27.60705 -34.27808 -22.71410 1.000 12.72956 ? 67  GLY C O   1 
ATOM   2819 N N   . LEU C 1 68  ? -25.47605 -34.73383 -22.12009 1.000 11.57304 ? 68  LEU C N   1 
ATOM   2820 C CA  . LEU C 1 68  ? -24.85402 -33.92012 -23.16592 1.000 11.43278 ? 68  LEU C CA  1 
ATOM   2821 C C   . LEU C 1 68  ? -24.11347 -34.86754 -24.09492 1.000 13.47199 ? 68  LEU C C   1 
ATOM   2822 O O   . LEU C 1 68  ? -23.21314 -35.58697 -23.64704 1.000 11.71210 ? 68  LEU C O   1 
ATOM   2823 C CB  . LEU C 1 68  ? -23.90561 -32.87156 -22.55688 1.000 9.99449  ? 68  LEU C CB  1 
ATOM   2824 C CG  . LEU C 1 68  ? -24.61055 -31.96842 -21.52177 1.000 9.58293  ? 68  LEU C CG  1 
ATOM   2825 C CD1 . LEU C 1 68  ? -23.60663 -31.06693 -20.80037 1.000 12.83615 ? 68  LEU C CD1 1 
ATOM   2826 C CD2 . LEU C 1 68  ? -25.60422 -31.09694 -22.21723 1.000 13.24546 ? 68  LEU C CD2 1 
ATOM   2827 N N   . HIS C 1 69  ? -24.52719 -34.89237 -25.37061 1.000 13.25991 ? 69  HIS C N   1 
ATOM   2828 C CA  . HIS C 1 69  ? -24.15158 -35.91585 -26.34421 1.000 15.53078 ? 69  HIS C CA  1 
ATOM   2829 C C   . HIS C 1 69  ? -23.56189 -35.27454 -27.59519 1.000 12.64254 ? 69  HIS C C   1 
ATOM   2830 O O   . HIS C 1 69  ? -23.80573 -34.10315 -27.89157 1.000 12.10086 ? 69  HIS C O   1 
ATOM   2831 C CB  . HIS C 1 69  ? -25.37706 -36.74248 -26.79151 1.000 15.57539 ? 69  HIS C CB  1 
ATOM   2832 C CG  . HIS C 1 69  ? -25.99584 -37.58274 -25.71528 1.000 16.80305 ? 69  HIS C CG  1 
ATOM   2833 N ND1 . HIS C 1 69  ? -27.09439 -38.38127 -25.95036 1.000 23.11793 ? 69  HIS C ND1 1 
ATOM   2834 C CD2 . HIS C 1 69  ? -25.65441 -37.78842 -24.42123 1.000 19.94244 ? 69  HIS C CD2 1 
ATOM   2835 C CE1 . HIS C 1 69  ? -27.42114 -39.02013 -24.84043 1.000 22.12577 ? 69  HIS C CE1 1 
ATOM   2836 N NE2 . HIS C 1 69  ? -26.56485 -38.67449 -23.89593 1.000 17.17104 ? 69  HIS C NE2 1 
ATOM   2837 N N   . ARG C 1 70  ? -22.79914 -36.06676 -28.34603 1.000 12.30122 ? 70  ARG C N   1 
ATOM   2838 C CA  . ARG C 1 70  ? -22.49186 -35.71905 -29.72659 1.000 11.40000 ? 70  ARG C CA  1 
ATOM   2839 C C   . ARG C 1 70  ? -23.71823 -35.81988 -30.62088 1.000 11.15687 ? 70  ARG C C   1 
ATOM   2840 O O   . ARG C 1 70  ? -24.50744 -36.76586 -30.51875 1.000 12.47154 ? 70  ARG C O   1 
ATOM   2841 C CB  . ARG C 1 70  ? -21.40429 -36.63708 -30.29480 1.000 13.16298 ? 70  ARG C CB  1 
ATOM   2842 C CG  . ARG C 1 70  ? -20.04558 -36.47279 -29.65685 1.000 16.08233 ? 70  ARG C CG  1 
ATOM   2843 C CD  . ARG C 1 70  ? -19.09774 -37.61337 -30.04601 1.000 18.14426 ? 70  ARG C CD  1 
ATOM   2844 N NE  . ARG C 1 70  ? -19.44974 -38.83797 -29.33661 1.000 21.90913 ? 70  ARG C NE  1 
ATOM   2845 C CZ  . ARG C 1 70  ? -19.05174 -40.05276 -29.67887 1.000 26.07577 ? 70  ARG C CZ  1 
ATOM   2846 N NH1 . ARG C 1 70  ? -18.28510 -40.25318 -30.73742 1.000 25.22836 ? 70  ARG C NH1 1 
ATOM   2847 N NH2 . ARG C 1 70  ? -19.41075 -41.08883 -28.92014 1.000 26.13461 ? 70  ARG C NH2 1 
ATOM   2848 N N   . GLU C 1 71  ? -23.83797 -34.86158 -31.53808 1.000 11.88546 ? 71  GLU C N   1 
ATOM   2849 C CA  . GLU C 1 71  ? -24.78067 -34.97789 -32.65000 1.000 11.10728 ? 71  GLU C CA  1 
ATOM   2850 C C   . GLU C 1 71  ? -24.49547 -36.22708 -33.47442 1.000 13.94658 ? 71  GLU C C   1 
ATOM   2851 O O   . GLU C 1 71  ? -23.34803 -36.66727 -33.59088 1.000 11.78086 ? 71  GLU C O   1 
ATOM   2852 C CB  . GLU C 1 71  ? -24.67653 -33.76018 -33.56556 1.000 12.07656 ? 71  GLU C CB  1 
ATOM   2853 C CG  . GLU C 1 71  ? -25.20638 -32.47546 -32.95903 1.000 14.79767 ? 71  GLU C CG  1 
ATOM   2854 C CD  . GLU C 1 71  ? -24.97546 -31.26363 -33.84728 1.000 17.62756 ? 71  GLU C CD  1 
ATOM   2855 O OE1 . GLU C 1 71  ? -24.25625 -31.38527 -34.86178 1.000 20.32162 ? 71  GLU C OE1 1 
ATOM   2856 O OE2 . GLU C 1 71  ? -25.49108 -30.17756 -33.50715 1.000 20.55319 ? 71  GLU C OE2 1 
ATOM   2857 N N   . GLY C 1 72  ? -25.55566 -36.78218 -34.07374 1.000 12.30594 ? 72  GLY C N   1 
ATOM   2858 C CA  . GLY C 1 72  ? -25.40844 -37.86516 -35.02823 1.000 12.43920 ? 72  GLY C CA  1 
ATOM   2859 C C   . GLY C 1 72  ? -26.23765 -39.11405 -34.79048 1.000 13.64971 ? 72  GLY C C   1 
ATOM   2860 O O   . GLY C 1 72  ? -26.25222 -40.01350 -35.63957 1.000 15.59311 ? 72  GLY C O   1 
ATOM   2861 N N   . ARG C 1 73  ? -26.90425 -39.21720 -33.64759 1.000 14.13817 ? 73  ARG C N   1 
ATOM   2862 C CA  . ARG C 1 73  ? -27.72214 -40.39440 -33.38286 1.000 13.89386 ? 73  ARG C CA  1 
ATOM   2863 C C   . ARG C 1 73  ? -29.17550 -40.14900 -33.77939 1.000 15.23274 ? 73  ARG C C   1 
ATOM   2864 O O   . ARG C 1 73  ? -29.62865 -39.01245 -33.91122 1.000 13.10833 ? 73  ARG C O   1 
ATOM   2865 C CB  . ARG C 1 73  ? -27.61743 -40.79397 -31.91802 1.000 16.06996 ? 73  ARG C CB  1 
ATOM   2866 C CG  . ARG C 1 73  ? -26.16945 -41.02337 -31.49778 1.000 22.91800 ? 73  ARG C CG  1 
ATOM   2867 C CD  . ARG C 1 73  ? -26.01872 -42.16189 -30.49993 1.000 26.20863 ? 73  ARG C CD  1 
ATOM   2868 N NE  . ARG C 1 73  ? -24.62241 -42.31546 -30.10339 1.000 22.95147 ? 73  ARG C NE  1 
ATOM   2869 C CZ  . ARG C 1 73  ? -23.95065 -41.47795 -29.32534 1.000 24.15332 ? 73  ARG C CZ  1 
ATOM   2870 N NH1 . ARG C 1 73  ? -24.53889 -40.43209 -28.74913 1.000 23.12807 ? 73  ARG C NH1 1 
ATOM   2871 N NH2 . ARG C 1 73  ? -22.64991 -41.68780 -29.12441 1.000 27.65771 ? 73  ARG C NH2 1 
ATOM   2872 N N   . SER C 1 74  ? -29.89318 -41.24267 -33.99995 1.000 12.11461 ? 74  SER C N   1 
ATOM   2873 C CA  . SER C 1 74  ? -31.28069 -41.18934 -34.43462 1.000 12.14578 ? 74  SER C CA  1 
ATOM   2874 C C   . SER C 1 74  ? -32.19623 -40.83541 -33.26387 1.000 16.21650 ? 74  SER C C   1 
ATOM   2875 O O   . SER C 1 74  ? -31.87270 -41.07467 -32.10231 1.000 13.65689 ? 74  SER C O   1 
ATOM   2876 C CB  . SER C 1 74  ? -31.68311 -42.53887 -35.02550 1.000 14.43311 ? 74  SER C CB  1 
ATOM   2877 O OG  . SER C 1 74  ? -31.94619 -43.47158 -33.98102 1.000 13.34367 ? 74  SER C OG  1 
ATOM   2878 N N   . ALA C 1 75  ? -33.36173 -40.27072 -33.59068 1.000 8.86009  ? 75  ALA C N   1 
ATOM   2879 C CA  . ALA C 1 75  ? -34.36390 -40.02030 -32.56127 1.000 14.35138 ? 75  ALA C CA  1 
ATOM   2880 C C   . ALA C 1 75  ? -34.81468 -41.32725 -31.93422 1.000 11.88361 ? 75  ALA C C   1 
ATOM   2881 O O   . ALA C 1 75  ? -35.02819 -41.40333 -30.71750 1.000 13.12268 ? 75  ALA C O   1 
ATOM   2882 C CB  . ALA C 1 75  ? -35.55116 -39.26015 -33.14989 1.000 13.30221 ? 75  ALA C CB  1 
ATOM   2883 N N   . ASP C 1 76  ? -34.93081 -42.37824 -32.75070 1.000 15.54322 ? 76  ASP C N   1 
ATOM   2884 C CA  . ASP C 1 76  ? -35.26632 -43.69855 -32.22323 1.000 16.08130 ? 76  ASP C CA  1 
ATOM   2885 C C   . ASP C 1 76  ? -34.28312 -44.12722 -31.13423 1.000 13.11499 ? 76  ASP C C   1 
ATOM   2886 O O   . ASP C 1 76  ? -34.68824 -44.55040 -30.04267 1.000 16.39592 ? 76  ASP C O   1 
ATOM   2887 C CB  . ASP C 1 76  ? -35.28980 -44.71295 -33.36586 1.000 16.66030 ? 76  ASP C CB  1 
ATOM   2888 C CG  . ASP C 1 76  ? -35.55499 -46.11665 -32.88136 1.000 30.31468 ? 76  ASP C CG  1 
ATOM   2889 O OD1 . ASP C 1 76  ? -36.42142 -46.27325 -32.00488 1.000 30.35727 ? 76  ASP C OD1 1 
ATOM   2890 O OD2 . ASP C 1 76  ? -34.88006 -47.05671 -33.35104 1.000 36.99011 ? 76  ASP C OD2 1 
ATOM   2891 N N   . LEU C 1 77  ? -32.97759 -44.01697 -31.40971 1.000 14.43033 ? 77  LEU C N   1 
ATOM   2892 C CA  . LEU C 1 77  ? -31.98315 -44.48678 -30.44457 1.000 16.33441 ? 77  LEU C CA  1 
ATOM   2893 C C   . LEU C 1 77  ? -31.96709 -43.60980 -29.19789 1.000 13.77021 ? 77  LEU C C   1 
ATOM   2894 O O   . LEU C 1 77  ? -31.90230 -44.12095 -28.07093 1.000 14.38540 ? 77  LEU C O   1 
ATOM   2895 C CB  . LEU C 1 77  ? -30.60356 -44.53227 -31.10063 1.000 16.00748 ? 77  LEU C CB  1 
ATOM   2896 C CG  . LEU C 1 77  ? -29.43486 -45.27071 -30.42245 1.000 23.13947 ? 77  LEU C CG  1 
ATOM   2897 C CD1 . LEU C 1 77  ? -28.76055 -44.42503 -29.33335 1.000 22.94326 ? 77  LEU C CD1 1 
ATOM   2898 C CD2 . LEU C 1 77  ? -29.92444 -46.59260 -29.84724 1.000 23.13912 ? 77  LEU C CD2 1 
ATOM   2899 N N   . LYS C 1 78  ? -32.04585 -42.28833 -29.37760 1.000 12.59471 ? 78  LYS C N   1 
ATOM   2900 C CA  . LYS C 1 78  ? -32.08439 -41.38782 -28.22978 1.000 13.64439 ? 78  LYS C CA  1 
ATOM   2901 C C   . LYS C 1 78  ? -33.30002 -41.67142 -27.36122 1.000 12.95669 ? 78  LYS C C   1 
ATOM   2902 O O   . LYS C 1 78  ? -33.21510 -41.63511 -26.13146 1.000 12.40025 ? 78  LYS C O   1 
ATOM   2903 C CB  . LYS C 1 78  ? -32.08183 -39.93396 -28.70185 1.000 15.12153 ? 78  LYS C CB  1 
ATOM   2904 C CG  . LYS C 1 78  ? -30.71162 -39.49116 -29.24641 1.000 14.79868 ? 78  LYS C CG  1 
ATOM   2905 C CD  . LYS C 1 78  ? -30.72329 -38.04478 -29.72944 1.000 12.46073 ? 78  LYS C CD  1 
ATOM   2906 C CE  . LYS C 1 78  ? -31.49351 -37.94968 -31.02774 1.000 14.43198 ? 78  LYS C CE  1 
ATOM   2907 N NZ  . LYS C 1 78  ? -31.45585 -36.56278 -31.57434 1.000 11.56309 ? 78  LYS C NZ  1 
ATOM   2908 N N   . GLY C 1 79  ? -34.43912 -41.96921 -27.98639 1.000 12.56159 ? 79  GLY C N   1 
ATOM   2909 C CA  . GLY C 1 79  ? -35.61159 -42.36101 -27.21746 1.000 13.66282 ? 79  GLY C CA  1 
ATOM   2910 C C   . GLY C 1 79  ? -35.39008 -43.61528 -26.39116 1.000 13.98570 ? 79  GLY C C   1 
ATOM   2911 O O   . GLY C 1 79  ? -35.77015 -43.67469 -25.21351 1.000 13.89634 ? 79  GLY C O   1 
ATOM   2912 N N   . GLN C 1 80  ? -34.81794 -44.65367 -27.00783 1.000 12.88138 ? 80  GLN C N   1 
ATOM   2913 C CA  . GLN C 1 80  ? -34.53365 -45.87907 -26.26958 1.000 13.14779 ? 80  GLN C CA  1 
ATOM   2914 C C   . GLN C 1 80  ? -33.59086 -45.59500 -25.11320 1.000 12.11604 ? 80  GLN C C   1 
ATOM   2915 O O   . GLN C 1 80  ? -33.76629 -46.12108 -24.00631 1.000 13.87452 ? 80  GLN C O   1 
ATOM   2916 C CB  . GLN C 1 80  ? -33.91020 -46.92217 -27.19467 1.000 14.12251 ? 80  GLN C CB  1 
ATOM   2917 C CG  . GLN C 1 80  ? -34.78651 -47.38749 -28.33136 1.000 18.31214 ? 80  GLN C CG  1 
ATOM   2918 C CD  . GLN C 1 80  ? -34.05465 -48.37810 -29.21460 1.000 28.66308 ? 80  GLN C CD  1 
ATOM   2919 O OE1 . GLN C 1 80  ? -33.34800 -49.25251 -28.71817 1.000 28.31076 ? 80  GLN C OE1 1 
ATOM   2920 N NE2 . GLN C 1 80  ? -34.17635 -48.21304 -30.53034 1.000 27.41871 ? 80  GLN C NE2 1 
ATOM   2921 N N   . LEU C 1 81  ? -32.57347 -44.77148 -25.36514 1.000 10.72939 ? 81  LEU C N   1 
ATOM   2922 C CA  . LEU C 1 81  ? -31.58745 -44.45138 -24.34164 1.000 12.61143 ? 81  LEU C CA  1 
ATOM   2923 C C   . LEU C 1 81  ? -32.21447 -43.66990 -23.18412 1.000 16.87215 ? 81  LEU C C   1 
ATOM   2924 O O   . LEU C 1 81  ? -31.94493 -43.96447 -22.00555 1.000 12.48029 ? 81  LEU C O   1 
ATOM   2925 C CB  . LEU C 1 81  ? -30.43990 -43.66887 -24.96922 1.000 12.18135 ? 81  LEU C CB  1 
ATOM   2926 C CG  . LEU C 1 81  ? -29.30454 -43.22135 -24.04955 1.000 10.95437 ? 81  LEU C CG  1 
ATOM   2927 C CD1 . LEU C 1 81  ? -28.81207 -44.39933 -23.24906 1.000 18.16464 ? 81  LEU C CD1 1 
ATOM   2928 C CD2 . LEU C 1 81  ? -28.19618 -42.65558 -24.94541 1.000 13.53679 ? 81  LEU C CD2 1 
ATOM   2929 N N   . ALA C 1 82  ? -33.06730 -42.68514 -23.49197 1.000 13.09756 ? 82  ALA C N   1 
ATOM   2930 C CA  . ALA C 1 82  ? -33.71965 -41.95113 -22.41106 1.000 14.11079 ? 82  ALA C CA  1 
ATOM   2931 C C   . ALA C 1 82  ? -34.65772 -42.85393 -21.62190 1.000 13.07420 ? 82  ALA C C   1 
ATOM   2932 O O   . ALA C 1 82  ? -34.72131 -42.76732 -20.38972 1.000 15.69938 ? 82  ALA C O   1 
ATOM   2933 C CB  . ALA C 1 82  ? -34.47956 -40.74733 -22.95637 1.000 12.52170 ? 82  ALA C CB  1 
ATOM   2934 N N   . GLN C 1 83  ? -35.39059 -43.73204 -22.30351 1.000 12.77777 ? 83  GLN C N   1 
ATOM   2935 C CA  . GLN C 1 83  ? -36.28301 -44.63828 -21.57941 1.000 15.38523 ? 83  GLN C CA  1 
ATOM   2936 C C   . GLN C 1 83  ? -35.50174 -45.59820 -20.68687 1.000 15.94801 ? 83  GLN C C   1 
ATOM   2937 O O   . GLN C 1 83  ? -35.92426 -45.89355 -19.55853 1.000 16.20780 ? 83  GLN C O   1 
ATOM   2938 C CB  . GLN C 1 83  ? -37.16582 -45.41200 -22.55651 1.000 15.69816 ? 83  GLN C CB  1 
ATOM   2939 C CG  . GLN C 1 83  ? -38.20690 -46.30265 -21.85864 1.000 21.47151 ? 83  GLN C CG  1 
ATOM   2940 C CD  . GLN C 1 83  ? -39.23505 -45.49825 -21.07282 1.000 24.18842 ? 83  GLN C CD  1 
ATOM   2941 O OE1 . GLN C 1 83  ? -39.98190 -44.70644 -21.64367 1.000 20.02173 ? 83  GLN C OE1 1 
ATOM   2942 N NE2 . GLN C 1 83  ? -39.27570 -45.70134 -19.75680 1.000 24.99879 ? 83  GLN C NE2 1 
ATOM   2943 N N   . ARG C 1 84  ? -34.36513 -46.10990 -21.17711 1.000 13.73982 ? 84  ARG C N   1 
ATOM   2944 C CA  . ARG C 1 84  ? -33.58536 -47.03633 -20.37476 1.000 16.53216 ? 84  ARG C CA  1 
ATOM   2945 C C   . ARG C 1 84  ? -32.95170 -46.32637 -19.18660 1.000 17.27851 ? 84  ARG C C   1 
ATOM   2946 O O   . ARG C 1 84  ? -32.80191 -46.92602 -18.11388 1.000 19.44387 ? 84  ARG C O   1 
ATOM   2947 C CB  . ARG C 1 84  ? -32.51152 -47.72481 -21.22815 1.000 15.33815 ? 84  ARG C CB  1 
ATOM   2948 C CG  . ARG C 1 84  ? -31.56140 -48.54471 -20.38598 1.000 21.09044 ? 84  ARG C CG  1 
ATOM   2949 C CD  . ARG C 1 84  ? -30.70169 -49.50733 -21.17017 1.000 24.93654 ? 84  ARG C CD  1 
ATOM   2950 N NE  . ARG C 1 84  ? -29.77152 -50.17213 -20.26324 1.000 27.77789 ? 84  ARG C NE  1 
ATOM   2951 C CZ  . ARG C 1 84  ? -28.84248 -51.04886 -20.62548 1.000 26.24840 ? 84  ARG C CZ  1 
ATOM   2952 N NH1 . ARG C 1 84  ? -28.71840 -51.44968 -21.88008 1.000 30.16094 ? 84  ARG C NH1 1 
ATOM   2953 N NH2 . ARG C 1 84  ? -27.99368 -51.50879 -19.70806 1.000 23.78640 ? 84  ARG C NH2 1 
ATOM   2954 N N   . ILE C 1 85  ? -32.58980 -45.05036 -19.34782 1.000 14.60629 ? 85  ILE C N   1 
ATOM   2955 C CA  . ILE C 1 85  ? -32.11150 -44.27470 -18.20386 1.000 15.03903 ? 85  ILE C CA  1 
ATOM   2956 C C   . ILE C 1 85  ? -33.22154 -44.11269 -17.16203 1.000 13.17375 ? 85  ILE C C   1 
ATOM   2957 O O   . ILE C 1 85  ? -32.99652 -44.34485 -15.97152 1.000 17.32292 ? 85  ILE C O   1 
ATOM   2958 C CB  . ILE C 1 85  ? -31.53588 -42.92264 -18.66468 1.000 14.46140 ? 85  ILE C CB  1 
ATOM   2959 C CG1 . ILE C 1 85  ? -30.16291 -43.16126 -19.29983 1.000 16.99470 ? 85  ILE C CG1 1 
ATOM   2960 C CG2 . ILE C 1 85  ? -31.40493 -41.93433 -17.49377 1.000 16.26270 ? 85  ILE C CG2 1 
ATOM   2961 C CD1 . ILE C 1 85  ? -29.56975 -41.95630 -19.98477 1.000 21.31325 ? 85  ILE C CD1 1 
ATOM   2962 N N   . VAL C 1 86  ? -34.43327 -43.74092 -17.58682 1.000 12.89940 ? 86  VAL C N   1 
ATOM   2963 C CA  . VAL C 1 86  ? -35.55276 -43.65431 -16.63505 1.000 14.46887 ? 86  VAL C CA  1 
ATOM   2964 C C   . VAL C 1 86  ? -35.74642 -44.99074 -15.91825 1.000 17.28663 ? 86  VAL C C   1 
ATOM   2965 O O   . VAL C 1 86  ? -35.84595 -45.05326 -14.68411 1.000 17.12010 ? 86  VAL C O   1 
ATOM   2966 C CB  . VAL C 1 86  ? -36.84631 -43.21647 -17.34534 1.000 15.98981 ? 86  VAL C CB  1 
ATOM   2967 C CG1 . VAL C 1 86  ? -38.06437 -43.33631 -16.39633 1.000 22.74545 ? 86  VAL C CG1 1 
ATOM   2968 C CG2 . VAL C 1 86  ? -36.72776 -41.80112 -17.88165 1.000 13.05389 ? 86  VAL C CG2 1 
ATOM   2969 N N   . ASP C 1 87  ? -35.79468 -46.08249 -16.68084 1.000 16.02942 ? 87  ASP C N   1 
ATOM   2970 C CA  . ASP C 1 87  ? -36.03025 -47.39297 -16.07539 1.000 20.43720 ? 87  ASP C CA  1 
ATOM   2971 C C   . ASP C 1 87  ? -34.90344 -47.77699 -15.11643 1.000 18.72384 ? 87  ASP C C   1 
ATOM   2972 O O   . ASP C 1 87  ? -35.15019 -48.21087 -13.98511 1.000 17.48304 ? 87  ASP C O   1 
ATOM   2973 C CB  . ASP C 1 87  ? -36.17433 -48.46569 -17.15953 1.000 19.52478 ? 87  ASP C CB  1 
ATOM   2974 C CG  . ASP C 1 87  ? -37.43712 -48.30776 -18.00246 1.000 24.30072 ? 87  ASP C CG  1 
ATOM   2975 O OD1 . ASP C 1 87  ? -38.42784 -47.69975 -17.55458 1.000 32.04715 ? 87  ASP C OD1 1 
ATOM   2976 O OD2 . ASP C 1 87  ? -37.46113 -48.87122 -19.11015 1.000 28.77249 ? 87  ASP C OD2 1 
ATOM   2977 N N   . ASP C 1 88  ? -33.65446 -47.65377 -15.55909 1.000 14.37102 ? 88  ASP C N   1 
ATOM   2978 C CA  . ASP C 1 88  ? -32.56504 -48.20582 -14.77069 1.000 16.92784 ? 88  ASP C CA  1 
ATOM   2979 C C   . ASP C 1 88  ? -32.17720 -47.29959 -13.61521 1.000 19.49726 ? 88  ASP C C   1 
ATOM   2980 O O   . ASP C 1 88  ? -31.66034 -47.78594 -12.60635 1.000 16.30556 ? 88  ASP C O   1 
ATOM   2981 C CB  . ASP C 1 88  ? -31.36472 -48.48332 -15.66868 1.000 22.58930 ? 88  ASP C CB  1 
ATOM   2982 C CG  . ASP C 1 88  ? -31.61632 -49.62244 -16.64124 1.000 22.18670 ? 88  ASP C CG  1 
ATOM   2983 O OD1 . ASP C 1 88  ? -32.70296 -50.24060 -16.59363 1.000 23.89851 ? 88  ASP C OD1 1 
ATOM   2984 O OD2 . ASP C 1 88  ? -30.71424 -49.90004 -17.45439 1.000 21.32912 ? 88  ASP C OD2 1 
ATOM   2985 N N   . VAL C 1 89  ? -32.40294 -45.98706 -13.74316 1.000 16.24931 ? 89  VAL C N   1 
ATOM   2986 C CA  . VAL C 1 89  ? -32.20027 -45.09637 -12.60878 1.000 16.86135 ? 89  VAL C CA  1 
ATOM   2987 C C   . VAL C 1 89  ? -33.29647 -45.30333 -11.56889 1.000 15.44483 ? 89  VAL C C   1 
ATOM   2988 O O   . VAL C 1 89  ? -33.05184 -45.19471 -10.36070 1.000 18.49230 ? 89  VAL C O   1 
ATOM   2989 C CB  . VAL C 1 89  ? -32.12657 -43.63312 -13.08015 1.000 19.10698 ? 89  VAL C CB  1 
ATOM   2990 C CG1 . VAL C 1 89  ? -32.23440 -42.66801 -11.89212 1.000 16.01820 ? 89  VAL C CG1 1 
ATOM   2991 C CG2 . VAL C 1 89  ? -30.82961 -43.38776 -13.86581 1.000 17.79949 ? 89  VAL C CG2 1 
ATOM   2992 N N   . SER C 1 90  ? -34.51702 -45.60051 -12.01253 1.000 14.59327 ? 90  SER C N   1 
ATOM   2993 C CA  . SER C 1 90  ? -35.60054 -45.85875 -11.06531 1.000 18.71473 ? 90  SER C CA  1 
ATOM   2994 C C   . SER C 1 90  ? -35.25429 -47.03088 -10.15229 1.000 23.50031 ? 90  SER C C   1 
ATOM   2995 O O   . SER C 1 90  ? -35.48516 -46.97869 -8.93492  1.000 18.68564 ? 90  SER C O   1 
ATOM   2996 C CB  . SER C 1 90  ? -36.89613 -46.12155 -11.82494 1.000 23.95778 ? 90  SER C CB  1 
ATOM   2997 O OG  . SER C 1 90  ? -37.96147 -46.42560 -10.93015 1.000 25.70719 ? 90  SER C OG  1 
ATOM   2998 N N   . VAL C 1 91  ? -34.65702 -48.07886 -10.72051 1.000 18.47923 ? 91  VAL C N   1 
ATOM   2999 C CA  . VAL C 1 91  ? -34.23256 -49.23289 -9.92943  1.000 20.01768 ? 91  VAL C CA  1 
ATOM   3000 C C   . VAL C 1 91  ? -33.03320 -48.87806 -9.05349  1.000 20.40949 ? 91  VAL C C   1 
ATOM   3001 O O   . VAL C 1 91  ? -33.02719 -49.13706 -7.84340  1.000 19.91820 ? 91  VAL C O   1 
ATOM   3002 C CB  . VAL C 1 91  ? -33.92243 -50.41750 -10.86035 1.000 18.30345 ? 91  VAL C CB  1 
ATOM   3003 C CG1 . VAL C 1 91  ? -33.31707 -51.55959 -10.07082 1.000 25.38433 ? 91  VAL C CG1 1 
ATOM   3004 C CG2 . VAL C 1 91  ? -35.18695 -50.86157 -11.56595 1.000 24.46468 ? 91  VAL C CG2 1 
ATOM   3005 N N   . ALA C 1 92  ? -31.99406 -48.28452 -9.65148  1.000 15.78148 ? 92  ALA C N   1 
ATOM   3006 C CA  . ALA C 1 92  ? -30.74242 -48.06846 -8.93854  1.000 18.67344 ? 92  ALA C CA  1 
ATOM   3007 C C   . ALA C 1 92  ? -30.91096 -47.11774 -7.76490  1.000 23.26103 ? 92  ALA C C   1 
ATOM   3008 O O   . ALA C 1 92  ? -30.22284 -47.25943 -6.74516  1.000 22.52485 ? 92  ALA C O   1 
ATOM   3009 C CB  . ALA C 1 92  ? -29.67553 -47.51802 -9.89070  1.000 15.68089 ? 92  ALA C CB  1 
ATOM   3010 N N   . ALA C 1 93  ? -31.78378 -46.12678 -7.89963  1.000 19.65213 ? 93  ALA C N   1 
ATOM   3011 C CA  . ALA C 1 93  ? -32.00190 -45.14477 -6.85115  1.000 24.50040 ? 93  ALA C CA  1 
ATOM   3012 C C   . ALA C 1 93  ? -33.20102 -45.47518 -5.97347  1.000 18.65908 ? 93  ALA C C   1 
ATOM   3013 O O   . ALA C 1 93  ? -33.45695 -44.74490 -5.01689  1.000 20.11682 ? 93  ALA C O   1 
ATOM   3014 C CB  . ALA C 1 93  ? -32.18386 -43.75305 -7.46909  1.000 21.16919 ? 93  ALA C CB  1 
ATOM   3015 N N   . GLU C 1 94  ? -33.91850 -46.55661 -6.27675  1.000 20.20196 ? 94  GLU C N   1 
ATOM   3016 C CA  . GLU C 1 94  ? -35.23914 -46.86976 -5.71739  1.000 22.74235 ? 94  GLU C CA  1 
ATOM   3017 C C   . GLU C 1 94  ? -36.09844 -45.61194 -5.60463  1.000 25.56314 ? 94  GLU C C   1 
ATOM   3018 O O   . GLU C 1 94  ? -36.53035 -45.18290 -4.53103  1.000 24.01189 ? 94  GLU C O   1 
ATOM   3019 C CB  . GLU C 1 94  ? -35.12776 -47.61474 -4.38258  1.000 31.24155 ? 94  GLU C CB  1 
ATOM   3020 C CG  . GLU C 1 94  ? -33.94237 -48.57022 -4.30334  1.000 30.94973 ? 94  GLU C CG  1 
ATOM   3021 C CD  . GLU C 1 94  ? -33.52121 -48.88302 -2.87560  1.000 41.27005 ? 94  GLU C CD  1 
ATOM   3022 O OE1 . GLU C 1 94  ? -34.29516 -48.57669 -1.94022  1.000 42.92137 ? 94  GLU C OE1 1 
ATOM   3023 O OE2 . GLU C 1 94  ? -32.41108 -49.42848 -2.68864  1.000 46.98507 ? 94  GLU C OE2 1 
ATOM   3024 N N   . ILE C 1 95  ? -36.34742 -45.03362 -6.76916  1.000 23.24506 ? 95  ILE C N   1 
ATOM   3025 C CA  . ILE C 1 95  ? -37.13614 -43.82137 -6.92526  1.000 22.44874 ? 95  ILE C CA  1 
ATOM   3026 C C   . ILE C 1 95  ? -38.18865 -44.08712 -7.98866  1.000 25.85037 ? 95  ILE C C   1 
ATOM   3027 O O   . ILE C 1 95  ? -37.89057 -44.69350 -9.02431  1.000 22.55154 ? 95  ILE C O   1 
ATOM   3028 C CB  . ILE C 1 95  ? -36.23496 -42.62844 -7.30498  1.000 20.87241 ? 95  ILE C CB  1 
ATOM   3029 C CG1 . ILE C 1 95  ? -36.96724 -41.28667 -7.12960  1.000 22.93964 ? 95  ILE C CG1 1 
ATOM   3030 C CG2 . ILE C 1 95  ? -35.59471 -42.81471 -8.68962  1.000 26.08772 ? 95  ILE C CG2 1 
ATOM   3031 C CD1 . ILE C 1 95  ? -36.00632 -40.11797 -7.12640  1.000 25.09280 ? 95  ILE C CD1 1 
ATOM   3032 N N   . ASP C 1 96  ? -39.42384 -43.65312 -7.74183  1.000 19.78990 ? 96  ASP C N   1 
ATOM   3033 C CA  . ASP C 1 96  ? -40.45424 -44.01710 -8.69796  1.000 20.26682 ? 96  ASP C CA  1 
ATOM   3034 C C   . ASP C 1 96  ? -40.26098 -43.15347 -9.94883  1.000 22.79422 ? 96  ASP C C   1 
ATOM   3035 O O   . ASP C 1 96  ? -39.75854 -42.02744 -9.87763  1.000 18.25067 ? 96  ASP C O   1 
ATOM   3036 C CB  . ASP C 1 96  ? -41.85672 -43.82761 -8.11460  1.000 29.36738 ? 96  ASP C CB  1 
ATOM   3037 C CG  . ASP C 1 96  ? -42.94953 -44.06079 -9.14563  1.000 38.65413 ? 96  ASP C CG  1 
ATOM   3038 O OD1 . ASP C 1 96  ? -43.40168 -43.12810 -9.81496  1.000 36.31023 ? 96  ASP C OD1 1 
ATOM   3039 O OD2 . ASP C 1 96  ? -43.38426 -45.22842 -9.26505  1.000 44.82593 ? 96  ASP C OD2 1 
ATOM   3040 N N   . ARG C 1 97  ? -40.63382 -43.70618 -11.10876 1.000 19.50088 ? 97  ARG C N   1 
ATOM   3041 C CA  . ARG C 1 97  ? -40.33930 -43.04764 -12.38125 1.000 18.94263 ? 97  ARG C CA  1 
ATOM   3042 C C   . ARG C 1 97  ? -40.99043 -41.67476 -12.50273 1.000 20.37393 ? 97  ARG C C   1 
ATOM   3043 O O   . ARG C 1 97  ? -40.51281 -40.83877 -13.28133 1.000 18.46997 ? 97  ARG C O   1 
ATOM   3044 C CB  . ARG C 1 97  ? -40.80396 -43.92694 -13.53788 1.000 21.18486 ? 97  ARG C CB  1 
ATOM   3045 C CG  . ARG C 1 97  ? -40.15521 -45.28199 -13.58141 1.000 29.92112 ? 97  ARG C CG  1 
ATOM   3046 C CD  . ARG C 1 97  ? -40.89287 -46.21737 -14.54170 1.000 31.27009 ? 97  ARG C CD  1 
ATOM   3047 N NE  . ARG C 1 97  ? -40.07142 -47.38449 -14.83242 1.000 33.83833 ? 97  ARG C NE  1 
ATOM   3048 C CZ  . ARG C 1 97  ? -39.93367 -48.41703 -14.01227 1.000 42.90210 ? 97  ARG C CZ  1 
ATOM   3049 N NH1 . ARG C 1 97  ? -40.57696 -48.47102 -12.85245 1.000 42.04247 ? 97  ARG C NH1 1 
ATOM   3050 N NH2 . ARG C 1 97  ? -39.11719 -49.41345 -14.35396 1.000 51.85571 ? 97  ARG C NH2 1 
ATOM   3051 N N   . LYS C 1 98  ? -42.09039 -41.41987 -11.77289 1.000 17.88204 ? 98  LYS C N   1 
ATOM   3052 C CA  . LYS C 1 98  ? -42.76072 -40.12488 -11.89656 1.000 16.53214 ? 98  LYS C CA  1 
ATOM   3053 C C   . LYS C 1 98  ? -41.86830 -38.98937 -11.41898 1.000 17.45945 ? 98  LYS C C   1 
ATOM   3054 O O   . LYS C 1 98  ? -42.16520 -37.82026 -11.68662 1.000 17.90957 ? 98  LYS C O   1 
ATOM   3055 C CB  . LYS C 1 98  ? -44.04661 -40.04832 -11.07195 1.000 22.49934 ? 98  LYS C CB  1 
ATOM   3056 C CG  . LYS C 1 98  ? -43.86079 -40.41822 -9.60415  1.000 30.98603 ? 98  LYS C CG  1 
ATOM   3057 C CD  . LYS C 1 98  ? -45.17417 -40.42500 -8.81819  1.000 30.51602 ? 98  LYS C CD  1 
ATOM   3058 C CE  . LYS C 1 98  ? -45.04870 -41.29458 -7.55734  1.000 39.76982 ? 98  LYS C CE  1 
ATOM   3059 N NZ  . LYS C 1 98  ? -46.24732 -41.22660 -6.67000  1.000 36.16696 ? 98  LYS C NZ  1 
ATOM   3060 N N   . HIS C 1 99  ? -40.82132 -39.30409 -10.66528 1.000 14.99233 ? 99  HIS C N   1 
ATOM   3061 C CA  . HIS C 1 99  ? -39.90690 -38.30545 -10.14461 1.000 16.05995 ? 99  HIS C CA  1 
ATOM   3062 C C   . HIS C 1 99  ? -38.74036 -38.02820 -11.07423 1.000 17.52527 ? 99  HIS C C   1 
ATOM   3063 O O   . HIS C 1 99  ? -37.88436 -37.20844 -10.72137 1.000 16.80297 ? 99  HIS C O   1 
ATOM   3064 C CB  . HIS C 1 99  ? -39.32955 -38.75136 -8.80250  1.000 18.77864 ? 99  HIS C CB  1 
ATOM   3065 C CG  . HIS C 1 99  ? -40.33772 -38.85834 -7.70214  1.000 19.66345 ? 99  HIS C CG  1 
ATOM   3066 N ND1 . HIS C 1 99  ? -41.04493 -37.77415 -7.22887  1.000 23.80155 ? 99  HIS C ND1 1 
ATOM   3067 C CD2 . HIS C 1 99  ? -40.70802 -39.91433 -6.94036  1.000 25.07480 ? 99  HIS C CD2 1 
ATOM   3068 C CE1 . HIS C 1 99  ? -41.83697 -38.16818 -6.24709  1.000 33.00904 ? 99  HIS C CE1 1 
ATOM   3069 N NE2 . HIS C 1 99  ? -41.64994 -39.46219 -6.05273  1.000 26.12778 ? 99  HIS C NE2 1 
ATOM   3070 N N   . ILE C 1 100 ? -38.65276 -38.71948 -12.20943 1.000 12.79999 ? 100 ILE C N   1 
ATOM   3071 C CA  . ILE C 1 100 ? -37.45060 -38.70011 -13.04389 1.000 15.82655 ? 100 ILE C CA  1 
ATOM   3072 C C   . ILE C 1 100 ? -37.69449 -37.86398 -14.29811 1.000 16.14131 ? 100 ILE C C   1 
ATOM   3073 O O   . ILE C 1 100 ? -38.61550 -38.13731 -15.08375 1.000 16.05971 ? 100 ILE C O   1 
ATOM   3074 C CB  . ILE C 1 100 ? -36.99055 -40.12029 -13.41692 1.000 17.23443 ? 100 ILE C CB  1 
ATOM   3075 C CG1 . ILE C 1 100 ? -36.76438 -40.95338 -12.15444 1.000 19.44277 ? 100 ILE C CG1 1 
ATOM   3076 C CG2 . ILE C 1 100 ? -35.70111 -40.05938 -14.23129 1.000 17.30758 ? 100 ILE C CG2 1 
ATOM   3077 C CD1 . ILE C 1 100 ? -36.26101 -42.34421 -12.43488 1.000 16.60145 ? 100 ILE C CD1 1 
ATOM   3078 N N   . TRP C 1 101 ? -36.82209 -36.87744 -14.50396 1.000 13.62302 ? 101 TRP C N   1 
ATOM   3079 C CA  . TRP C 1 101 ? -36.78946 -36.03867 -15.69444 1.000 11.84137 ? 101 TRP C CA  1 
ATOM   3080 C C   . TRP C 1 101 ? -35.44894 -36.26843 -16.38922 1.000 13.16019 ? 101 TRP C C   1 
ATOM   3081 O O   . TRP C 1 101 ? -34.41525 -36.36981 -15.72116 1.000 12.46550 ? 101 TRP C O   1 
ATOM   3082 C CB  . TRP C 1 101 ? -36.94500 -34.55150 -15.32408 1.000 11.80460 ? 101 TRP C CB  1 
ATOM   3083 C CG  . TRP C 1 101 ? -38.25415 -34.18155 -14.66444 1.000 13.66898 ? 101 TRP C CG  1 
ATOM   3084 C CD1 . TRP C 1 101 ? -38.98042 -34.92705 -13.76829 1.000 15.31466 ? 101 TRP C CD1 1 
ATOM   3085 C CD2 . TRP C 1 101 ? -38.98832 -32.96958 -14.86821 1.000 13.33183 ? 101 TRP C CD2 1 
ATOM   3086 N NE1 . TRP C 1 101 ? -40.12712 -34.24168 -13.40164 1.000 15.74191 ? 101 TRP C NE1 1 
ATOM   3087 C CE2 . TRP C 1 101 ? -40.14580 -33.03445 -14.05545 1.000 15.42855 ? 101 TRP C CE2 1 
ATOM   3088 C CE3 . TRP C 1 101 ? -38.76925 -31.82313 -15.64017 1.000 14.72751 ? 101 TRP C CE3 1 
ATOM   3089 C CZ2 . TRP C 1 101 ? -41.09138 -32.00457 -14.02078 1.000 17.33557 ? 101 TRP C CZ2 1 
ATOM   3090 C CZ3 . TRP C 1 101 ? -39.70342 -30.79464 -15.59094 1.000 13.12755 ? 101 TRP C CZ3 1 
ATOM   3091 C CH2 . TRP C 1 101 ? -40.85673 -30.90309 -14.79946 1.000 15.85795 ? 101 TRP C CH2 1 
ATOM   3092 N N   . VAL C 1 102 ? -35.46891 -36.35593 -17.72359 1.000 13.51569 ? 102 VAL C N   1 
ATOM   3093 C CA  . VAL C 1 102 ? -34.28025 -36.64619 -18.52914 1.000 10.70054 ? 102 VAL C CA  1 
ATOM   3094 C C   . VAL C 1 102 ? -34.33312 -35.79450 -19.79272 1.000 11.98934 ? 102 VAL C C   1 
ATOM   3095 O O   . VAL C 1 102 ? -35.26647 -35.93776 -20.59133 1.000 10.14053 ? 102 VAL C O   1 
ATOM   3096 C CB  . VAL C 1 102 ? -34.18152 -38.13678 -18.91453 1.000 11.53741 ? 102 VAL C CB  1 
ATOM   3097 C CG1 . VAL C 1 102 ? -32.93645 -38.38038 -19.74199 1.000 13.27821 ? 102 VAL C CG1 1 
ATOM   3098 C CG2 . VAL C 1 102 ? -34.18138 -39.05623 -17.68121 1.000 14.84294 ? 102 VAL C CG2 1 
ATOM   3099 N N   . TYR C 1 103 ? -33.31986 -34.93452 -19.99653 1.000 12.16704 ? 103 TYR C N   1 
ATOM   3100 C CA  . TYR C 1 103 ? -33.18704 -34.11775 -21.20847 1.000 12.24865 ? 103 TYR C CA  1 
ATOM   3101 C C   . TYR C 1 103 ? -31.84805 -34.41493 -21.87225 1.000 8.99410  ? 103 TYR C C   1 
ATOM   3102 O O   . TYR C 1 103 ? -30.81909 -34.42890 -21.18846 1.000 11.37389 ? 103 TYR C O   1 
ATOM   3103 C CB  . TYR C 1 103 ? -33.21019 -32.60609 -20.91496 1.000 10.18860 ? 103 TYR C CB  1 
ATOM   3104 C CG  . TYR C 1 103 ? -34.50394 -31.95162 -20.46985 1.000 10.97616 ? 103 TYR C CG  1 
ATOM   3105 C CD1 . TYR C 1 103 ? -35.68500 -32.66502 -20.34938 1.000 12.55351 ? 103 TYR C CD1 1 
ATOM   3106 C CD2 . TYR C 1 103 ? -34.53105 -30.57486 -20.22178 1.000 11.51618 ? 103 TYR C CD2 1 
ATOM   3107 C CE1 . TYR C 1 103 ? -36.87573 -32.01305 -19.95631 1.000 9.40115  ? 103 TYR C CE1 1 
ATOM   3108 C CE2 . TYR C 1 103 ? -35.70318 -29.91937 -19.82428 1.000 12.82966 ? 103 TYR C CE2 1 
ATOM   3109 C CZ  . TYR C 1 103 ? -36.86329 -30.63397 -19.70652 1.000 10.46801 ? 103 TYR C CZ  1 
ATOM   3110 O OH  . TYR C 1 103 ? -37.99679 -29.97438 -19.32411 1.000 15.02608 ? 103 TYR C OH  1 
ATOM   3111 N N   . PHE C 1 104 ? -31.85275 -34.61795 -23.18808 1.000 11.79993 ? 104 PHE C N   1 
ATOM   3112 C CA  . PHE C 1 104 ? -30.62349 -34.78841 -23.97237 1.000 9.08774  ? 104 PHE C CA  1 
ATOM   3113 C C   . PHE C 1 104 ? -30.36417 -33.55596 -24.83252 1.000 12.96969 ? 104 PHE C C   1 
ATOM   3114 O O   . PHE C 1 104 ? -31.22214 -33.15901 -25.62972 1.000 11.99175 ? 104 PHE C O   1 
ATOM   3115 C CB  . PHE C 1 104 ? -30.69646 -36.00422 -24.90964 1.000 9.70743  ? 104 PHE C CB  1 
ATOM   3116 C CG  . PHE C 1 104 ? -30.74650 -37.34319 -24.21501 1.000 10.92187 ? 104 PHE C CG  1 
ATOM   3117 C CD1 . PHE C 1 104 ? -30.44557 -37.47263 -22.87787 1.000 12.54011 ? 104 PHE C CD1 1 
ATOM   3118 C CD2 . PHE C 1 104 ? -31.09944 -38.48295 -24.93011 1.000 12.05737 ? 104 PHE C CD2 1 
ATOM   3119 C CE1 . PHE C 1 104 ? -30.51353 -38.70893 -22.26128 1.000 14.57925 ? 104 PHE C CE1 1 
ATOM   3120 C CE2 . PHE C 1 104 ? -31.15744 -39.72308 -24.32215 1.000 11.62969 ? 104 PHE C CE2 1 
ATOM   3121 C CZ  . PHE C 1 104 ? -30.86424 -39.83907 -22.99367 1.000 15.67363 ? 104 PHE C CZ  1 
ATOM   3122 N N   . GLY C 1 105 ? -29.16316 -33.00297 -24.72291 1.000 13.61977 ? 105 GLY C N   1 
ATOM   3123 C CA  . GLY C 1 105 ? -28.68894 -31.96676 -25.62489 1.000 11.88065 ? 105 GLY C CA  1 
ATOM   3124 C C   . GLY C 1 105 ? -27.55742 -32.52964 -26.46107 1.000 15.54300 ? 105 GLY C C   1 
ATOM   3125 O O   . GLY C 1 105 ? -26.83157 -33.42237 -26.01781 1.000 16.05821 ? 105 GLY C O   1 
ATOM   3126 N N   . GLU C 1 106 ? -27.43085 -32.03605 -27.69174 1.000 13.17497 ? 106 GLU C N   1 
ATOM   3127 C CA  . GLU C 1 106 ? -26.40445 -32.51904 -28.60992 1.000 9.76497  ? 106 GLU C CA  1 
ATOM   3128 C C   . GLU C 1 106 ? -25.59785 -31.35679 -29.16114 1.000 13.46280 ? 106 GLU C C   1 
ATOM   3129 O O   . GLU C 1 106 ? -26.13946 -30.27649 -29.41945 1.000 13.46932 ? 106 GLU C O   1 
ATOM   3130 C CB  . GLU C 1 106 ? -27.01292 -33.27558 -29.79007 1.000 15.79929 ? 106 GLU C CB  1 
ATOM   3131 C CG  . GLU C 1 106 ? -27.95519 -34.36256 -29.39963 1.000 14.87892 ? 106 GLU C CG  1 
ATOM   3132 C CD  . GLU C 1 106 ? -28.93316 -34.65092 -30.50875 1.000 16.08084 ? 106 GLU C CD  1 
ATOM   3133 O OE1 . GLU C 1 106 ? -29.95740 -33.94832 -30.57100 1.000 16.87180 ? 106 GLU C OE1 1 
ATOM   3134 O OE2 . GLU C 1 106 ? -28.66990 -35.55299 -31.32978 1.000 15.92793 ? 106 GLU C OE2 1 
ATOM   3135 N N   . MET C 1 107 ? -24.30689 -31.59460 -29.35921 1.000 11.87548 ? 107 MET C N   1 
ATOM   3136 C CA  . MET C 1 107 ? -23.39052 -30.66445 -29.99897 1.000 12.24586 ? 107 MET C CA  1 
ATOM   3137 C C   . MET C 1 107 ? -22.50170 -31.38482 -30.99756 1.000 10.89496 ? 107 MET C C   1 
ATOM   3138 O O   . MET C 1 107 ? -22.32711 -32.60655 -30.92151 1.000 11.69065 ? 107 MET C O   1 
ATOM   3139 C CB  . MET C 1 107 ? -22.53945 -29.91240 -28.95747 1.000 14.05331 ? 107 MET C CB  1 
ATOM   3140 C CG  . MET C 1 107 ? -23.30456 -29.59313 -27.69966 1.000 15.39441 ? 107 MET C CG  1 
ATOM   3141 S SD  . MET C 1 107 ? -22.33320 -29.57861 -26.19449 1.000 18.16461 ? 107 MET C SD  1 
ATOM   3142 C CE  . MET C 1 107 ? -22.75724 -31.23734 -25.79683 1.000 14.07254 ? 107 MET C CE  1 
ATOM   3143 N N   . PRO C 1 108 ? -21.98994 -30.66243 -31.99020 1.000 11.56685 ? 108 PRO C N   1 
ATOM   3144 C CA  . PRO C 1 108 ? -21.02104 -31.27015 -32.91252 1.000 13.25239 ? 108 PRO C CA  1 
ATOM   3145 C C   . PRO C 1 108 ? -19.82718 -31.80860 -32.14733 1.000 10.57198 ? 108 PRO C C   1 
ATOM   3146 O O   . PRO C 1 108 ? -19.32105 -31.16373 -31.23053 1.000 13.44355 ? 108 PRO C O   1 
ATOM   3147 C CB  . PRO C 1 108 ? -20.62132 -30.10347 -33.82825 1.000 17.66937 ? 108 PRO C CB  1 
ATOM   3148 C CG  . PRO C 1 108 ? -21.77193 -29.15056 -33.74582 1.000 16.89350 ? 108 PRO C CG  1 
ATOM   3149 C CD  . PRO C 1 108 ? -22.31664 -29.27353 -32.34883 1.000 15.76011 ? 108 PRO C CD  1 
ATOM   3150 N N   . ALA C 1 109 ? -19.39268 -33.01721 -32.52741 1.000 16.44858 ? 109 ALA C N   1 
ATOM   3151 C CA  . ALA C 1 109 ? -18.22545 -33.63471 -31.90772 1.000 15.09179 ? 109 ALA C CA  1 
ATOM   3152 C C   . ALA C 1 109 ? -16.99691 -32.73951 -31.98014 1.000 12.94711 ? 109 ALA C C   1 
ATOM   3153 O O   . ALA C 1 109 ? -16.14975 -32.78829 -31.08133 1.000 13.24915 ? 109 ALA C O   1 
ATOM   3154 C CB  . ALA C 1 109 ? -17.92060 -34.97418 -32.58041 1.000 14.75267 ? 109 ALA C CB  1 
ATOM   3155 N N   . GLN C 1 110 ? -16.87233 -31.93763 -33.04878 1.000 16.44336 ? 110 GLN C N   1 
ATOM   3156 C CA  . GLN C 1 110 ? -15.74465 -31.02491 -33.21441 1.000 15.18728 ? 110 GLN C CA  1 
ATOM   3157 C C   . GLN C 1 110 ? -15.65431 -29.93766 -32.15056 1.000 15.10309 ? 110 GLN C C   1 
ATOM   3158 O O   . GLN C 1 110 ? -14.62708 -29.25167 -32.10115 1.000 16.63573 ? 110 GLN C O   1 
ATOM   3159 C CB  . GLN C 1 110 ? -15.75734 -30.34208 -34.60838 1.000 16.36056 ? 110 GLN C CB  1 
ATOM   3160 C CG  . GLN C 1 110 ? -15.88605 -31.24246 -35.86442 1.000 28.03784 ? 110 GLN C CG  1 
ATOM   3161 C CD  . GLN C 1 110 ? -17.01942 -32.26238 -35.86105 1.000 31.39317 ? 110 GLN C CD  1 
ATOM   3162 O OE1 . GLN C 1 110 ? -18.18937 -31.92526 -35.65700 1.000 19.58102 ? 110 GLN C OE1 1 
ATOM   3163 N NE2 . GLN C 1 110 ? -16.66909 -33.52880 -36.12657 1.000 33.22278 ? 110 GLN C NE2 1 
ATOM   3164 N N   . GLN C 1 111 ? -16.68284 -29.72536 -31.32290 1.000 11.47182 ? 111 GLN C N   1 
ATOM   3165 C CA  . GLN C 1 111 ? -16.56824 -28.75797 -30.23354 1.000 15.15346 ? 111 GLN C CA  1 
ATOM   3166 C C   . GLN C 1 111 ? -16.77997 -29.45388 -28.88445 1.000 13.05414 ? 111 GLN C C   1 
ATOM   3167 O O   . GLN C 1 111 ? -17.38826 -28.91535 -27.94863 1.000 11.85205 ? 111 GLN C O   1 
ATOM   3168 C CB  . GLN C 1 111 ? -17.53259 -27.58665 -30.41739 1.000 10.41700 ? 111 GLN C CB  1 
ATOM   3169 C CG  . GLN C 1 111 ? -19.01253 -27.95668 -30.41153 1.000 12.28567 ? 111 GLN C CG  1 
ATOM   3170 C CD  . GLN C 1 111 ? -19.85169 -26.93430 -31.15416 1.000 14.15276 ? 111 GLN C CD  1 
ATOM   3171 O OE1 . GLN C 1 111 ? -19.62399 -26.66549 -32.34225 1.000 14.05056 ? 111 GLN C OE1 1 
ATOM   3172 N NE2 . GLN C 1 111 ? -20.84284 -26.37081 -30.46553 1.000 12.61978 ? 111 GLN C NE2 1 
ATOM   3173 N N   . MET C 1 112 ? -16.17110 -30.62852 -28.75285 1.000 14.31555 ? 112 MET C N   1 
ATOM   3174 C CA  . MET C 1 112 ? -16.44844 -31.57483 -27.68163 1.000 11.51010 ? 112 MET C CA  1 
ATOM   3175 C C   . MET C 1 112 ? -15.09632 -32.19716 -27.35997 1.000 13.47781 ? 112 MET C C   1 
ATOM   3176 O O   . MET C 1 112 ? -14.49143 -32.81321 -28.23999 1.000 13.49381 ? 112 MET C O   1 
ATOM   3177 C CB  . MET C 1 112 ? -17.42160 -32.59485 -28.26192 1.000 20.18904 ? 112 MET C CB  1 
ATOM   3178 C CG  . MET C 1 112 ? -18.87914 -32.10513 -28.29149 1.000 17.22587 ? 112 MET C CG  1 
ATOM   3179 S SD  . MET C 1 112 ? -20.21538 -33.26645 -28.14801 1.000 14.66157 ? 112 MET C SD  1 
ATOM   3180 C CE  . MET C 1 112 ? -20.00749 -34.09455 -26.56844 1.000 12.25327 ? 112 MET C CE  1 
ATOM   3181 N N   . VAL C 1 113 ? -14.59778 -31.99461 -26.14136 1.000 12.75994 ? 113 VAL C N   1 
ATOM   3182 C CA  . VAL C 1 113 ? -13.26822 -32.42433 -25.71776 1.000 11.07386 ? 113 VAL C CA  1 
ATOM   3183 C C   . VAL C 1 113 ? -13.43316 -33.31034 -24.49364 1.000 9.24173  ? 113 VAL C C   1 
ATOM   3184 O O   . VAL C 1 113 ? -14.06573 -32.89880 -23.51758 1.000 11.84967 ? 113 VAL C O   1 
ATOM   3185 C CB  . VAL C 1 113 ? -12.36826 -31.20867 -25.39680 1.000 11.07035 ? 113 VAL C CB  1 
ATOM   3186 C CG1 . VAL C 1 113 ? -11.07249 -31.61709 -24.67980 1.000 10.73565 ? 113 VAL C CG1 1 
ATOM   3187 C CG2 . VAL C 1 113 ? -12.01857 -30.46350 -26.68068 1.000 12.35955 ? 113 VAL C CG2 1 
ATOM   3188 N N   . GLN C 1 114 ? -12.83122 -34.50379 -24.52729 1.000 11.87456 ? 114 GLN C N   1 
ATOM   3189 C CA  . GLN C 1 114 ? -12.76986 -35.39449 -23.37015 1.000 11.31468 ? 114 GLN C CA  1 
ATOM   3190 C C   . GLN C 1 114 ? -11.32433 -35.84564 -23.19792 1.000 14.82976 ? 114 GLN C C   1 
ATOM   3191 O O   . GLN C 1 114 ? -10.64835 -36.13333 -24.18606 1.000 12.75517 ? 114 GLN C O   1 
ATOM   3192 C CB  . GLN C 1 114 ? -13.68946 -36.60032 -23.57987 1.000 12.63828 ? 114 GLN C CB  1 
ATOM   3193 C CG  . GLN C 1 114 ? -15.15832 -36.16478 -23.60568 1.000 13.33311 ? 114 GLN C CG  1 
ATOM   3194 C CD  . GLN C 1 114 ? -16.15772 -37.30219 -23.64684 1.000 14.88918 ? 114 GLN C CD  1 
ATOM   3195 O OE1 . GLN C 1 114 ? -17.34261 -37.07640 -23.93939 1.000 16.19138 ? 114 GLN C OE1 1 
ATOM   3196 N NE2 . GLN C 1 114 ? -15.70013 -38.53017 -23.39443 1.000 13.82022 ? 114 GLN C NE2 1 
ATOM   3197 N N   . TYR C 1 115 ? -10.83918 -35.88399 -21.95296 1.000 14.34587 ? 115 TYR C N   1 
ATOM   3198 C CA  . TYR C 1 115 ? -9.44382  -36.27692 -21.69568 1.000 13.24805 ? 115 TYR C CA  1 
ATOM   3199 C C   . TYR C 1 115 ? -8.47301  -35.38036 -22.46095 1.000 14.64209 ? 115 TYR C C   1 
ATOM   3200 O O   . TYR C 1 115 ? -7.41320  -35.82610 -22.92712 1.000 15.88954 ? 115 TYR C O   1 
ATOM   3201 C CB  . TYR C 1 115 ? -9.20559  -37.74966 -22.05824 1.000 12.98516 ? 115 TYR C CB  1 
ATOM   3202 C CG  . TYR C 1 115 ? -9.99844  -38.74489 -21.21259 1.000 15.34247 ? 115 TYR C CG  1 
ATOM   3203 C CD1 . TYR C 1 115 ? -9.54649  -39.14397 -19.95699 1.000 17.73992 ? 115 TYR C CD1 1 
ATOM   3204 C CD2 . TYR C 1 115 ? -11.19788 -39.27623 -21.67105 1.000 13.99312 ? 115 TYR C CD2 1 
ATOM   3205 C CE1 . TYR C 1 115 ? -10.26133 -40.04521 -19.18903 1.000 18.22957 ? 115 TYR C CE1 1 
ATOM   3206 C CE2 . TYR C 1 115 ? -11.92909 -40.17585 -20.90071 1.000 14.27342 ? 115 TYR C CE2 1 
ATOM   3207 C CZ  . TYR C 1 115 ? -11.45253 -40.55183 -19.66390 1.000 20.07266 ? 115 TYR C CZ  1 
ATOM   3208 O OH  . TYR C 1 115 ? -12.16850 -41.45372 -18.91447 1.000 16.85142 ? 115 TYR C OH  1 
ATOM   3209 N N   . GLY C 1 116 ? -8.83660  -34.10860 -22.62694 1.000 14.25460 ? 116 GLY C N   1 
ATOM   3210 C CA  . GLY C 1 116 ? -7.99602  -33.17478 -23.34995 1.000 15.65076 ? 116 GLY C CA  1 
ATOM   3211 C C   . GLY C 1 116 ? -7.92565  -33.38414 -24.84595 1.000 15.60469 ? 116 GLY C C   1 
ATOM   3212 O O   . GLY C 1 116 ? -7.12609  -32.70941 -25.51425 1.000 17.83698 ? 116 GLY C O   1 
ATOM   3213 N N   . ARG C 1 117 ? -8.74348  -34.27630 -25.40366 1.000 16.30438 ? 117 ARG C N   1 
ATOM   3214 C CA  . ARG C 1 117 ? -8.73257  -34.54974 -26.83395 1.000 14.52669 ? 117 ARG C CA  1 
ATOM   3215 C C   . ARG C 1 117 ? -10.11858 -34.30855 -27.42443 1.000 13.53285 ? 117 ARG C C   1 
ATOM   3216 O O   . ARG C 1 117 ? -11.13652 -34.56530 -26.78374 1.000 13.98842 ? 117 ARG C O   1 
ATOM   3217 C CB  . ARG C 1 117 ? -8.27714  -35.99860 -27.12914 1.000 15.50358 ? 117 ARG C CB  1 
ATOM   3218 C CG  . ARG C 1 117 ? -6.85544  -36.31512 -26.67516 1.000 21.03953 ? 117 ARG C CG  1 
ATOM   3219 C CD  . ARG C 1 117 ? -5.82219  -35.46857 -27.41011 1.000 26.79553 ? 117 ARG C CD  1 
ATOM   3220 N NE  . ARG C 1 117 ? -5.86449  -35.72567 -28.84543 1.000 28.33682 ? 117 ARG C NE  1 
ATOM   3221 C CZ  . ARG C 1 117 ? -5.02899  -36.52777 -29.49506 1.000 36.35452 ? 117 ARG C CZ  1 
ATOM   3222 N NH1 . ARG C 1 117 ? -4.05600  -37.16836 -28.86925 1.000 34.77897 ? 117 ARG C NH1 1 
ATOM   3223 N NH2 . ARG C 1 117 ? -5.17403  -36.69190 -30.80652 1.000 37.44714 ? 117 ARG C NH2 1 
ATOM   3224 N N   . PHE C 1 118 ? -10.14846 -33.82004 -28.66288 1.000 16.22749 ? 118 PHE C N   1 
ATOM   3225 C CA  . PHE C 1 118 ? -11.41334 -33.67492 -29.36993 1.000 14.70683 ? 118 PHE C CA  1 
ATOM   3226 C C   . PHE C 1 118 ? -11.99281 -35.04127 -29.71161 1.000 14.89396 ? 118 PHE C C   1 
ATOM   3227 O O   . PHE C 1 118 ? -11.26657 -35.96421 -30.09451 1.000 15.20957 ? 118 PHE C O   1 
ATOM   3228 C CB  . PHE C 1 118 ? -11.20690 -32.85526 -30.64520 1.000 18.46515 ? 118 PHE C CB  1 
ATOM   3229 C CG  . PHE C 1 118 ? -11.05071 -31.39230 -30.38606 1.000 16.48951 ? 118 PHE C CG  1 
ATOM   3230 C CD1 . PHE C 1 118 ? -9.79685  -30.84983 -30.15457 1.000 16.57550 ? 118 PHE C CD1 1 
ATOM   3231 C CD2 . PHE C 1 118 ? -12.16161 -30.56390 -30.33176 1.000 14.93360 ? 118 PHE C CD2 1 
ATOM   3232 C CE1 . PHE C 1 118 ? -9.63445  -29.50224 -29.89883 1.000 19.13358 ? 118 PHE C CE1 1 
ATOM   3233 C CE2 . PHE C 1 118 ? -12.01131 -29.20250 -30.08460 1.000 20.38711 ? 118 PHE C CE2 1 
ATOM   3234 C CZ  . PHE C 1 118 ? -10.74663 -28.67295 -29.85803 1.000 21.13195 ? 118 PHE C CZ  1 
ATOM   3235 N N   . LEU C 1 119 ? -13.31883 -35.16575 -29.57399 1.000 13.67929 ? 119 LEU C N   1 
ATOM   3236 C CA  . LEU C 1 119 ? -14.02258 -36.41159 -29.83768 1.000 16.04479 ? 119 LEU C CA  1 
ATOM   3237 C C   . LEU C 1 119 ? -14.15058 -36.70496 -31.33260 1.000 16.68996 ? 119 LEU C C   1 
ATOM   3238 O O   . LEU C 1 119 ? -14.11346 -35.79604 -32.17233 1.000 15.22347 ? 119 LEU C O   1 
ATOM   3239 C CB  . LEU C 1 119 ? -15.41954 -36.36741 -29.20984 1.000 18.02029 ? 119 LEU C CB  1 
ATOM   3240 C CG  . LEU C 1 119 ? -15.50861 -36.44363 -27.68300 1.000 16.97451 ? 119 LEU C CG  1 
ATOM   3241 C CD1 . LEU C 1 119 ? -16.98978 -36.40748 -27.25051 1.000 15.54530 ? 119 LEU C CD1 1 
ATOM   3242 C CD2 . LEU C 1 119 ? -14.83524 -37.69730 -27.14067 1.000 16.72233 ? 119 LEU C CD2 1 
ATOM   3243 N N   . PRO C 1 120 ? -14.33538 -37.98227 -31.68611 1.000 16.14078 ? 120 PRO C N   1 
ATOM   3244 C CA  . PRO C 1 120 ? -14.64044 -38.34123 -33.07092 1.000 21.36796 ? 120 PRO C CA  1 
ATOM   3245 C C   . PRO C 1 120 ? -16.13537 -38.36852 -33.33618 1.000 20.26979 ? 120 PRO C C   1 
ATOM   3246 O O   . PRO C 1 120 ? -16.91775 -38.21091 -32.40493 1.000 18.18135 ? 120 PRO C O   1 
ATOM   3247 C CB  . PRO C 1 120 ? -14.05837 -39.75050 -33.17651 1.000 20.96276 ? 120 PRO C CB  1 
ATOM   3248 C CG  . PRO C 1 120 ? -14.26114 -40.31960 -31.78233 1.000 19.97858 ? 120 PRO C CG  1 
ATOM   3249 C CD  . PRO C 1 120 ? -14.43852 -39.16302 -30.81159 1.000 17.20908 ? 120 PRO C CD  1 
ATOM   3250 N N   . GLN C 1 121 ? -16.54287 -38.65862 -34.57379 1.000 26.92263 ? 121 GLN C N   1 
ATOM   3251 C CA  . GLN C 1 121 ? -17.95713 -38.86722 -34.85649 1.000 27.89551 ? 121 GLN C CA  1 
ATOM   3252 C C   . GLN C 1 121 ? -18.47746 -40.13149 -34.16434 1.000 28.24714 ? 121 GLN C C   1 
ATOM   3253 O O   . GLN C 1 121 ? -17.74187 -41.11178 -34.00615 1.000 29.77347 ? 121 GLN C O   1 
ATOM   3254 C CB  . GLN C 1 121 ? -18.19033 -38.97393 -36.35979 1.000 35.02203 ? 121 GLN C CB  1 
ATOM   3255 C CG  . GLN C 1 121 ? -18.05594 -37.65441 -37.13935 1.000 34.78034 ? 121 GLN C CG  1 
ATOM   3256 C CD  . GLN C 1 121 ? -18.76468 -36.46015 -36.47734 1.000 32.14834 ? 121 GLN C CD  1 
ATOM   3257 O OE1 . GLN C 1 121 ? -18.25019 -35.33952 -36.48593 1.000 32.76912 ? 121 GLN C OE1 1 
ATOM   3258 N NE2 . GLN C 1 121 ? -19.93456 -36.70117 -35.89588 1.000 24.52500 ? 121 GLN C NE2 1 
ATOM   3259 N N   . PRO C 1 122 ? -19.74633 -40.14016 -33.74353 1.000 28.67069 ? 122 PRO C N   1 
ATOM   3260 C CA  . PRO C 1 122 ? -20.28944 -41.34592 -33.10105 1.000 29.97233 ? 122 PRO C CA  1 
ATOM   3261 C C   . PRO C 1 122 ? -20.15875 -42.55772 -34.00768 1.000 33.36202 ? 122 PRO C C   1 
ATOM   3262 O O   . PRO C 1 122 ? -20.34729 -42.47168 -35.22541 1.000 30.66276 ? 122 PRO C O   1 
ATOM   3263 C CB  . PRO C 1 122 ? -21.75598 -40.98531 -32.83362 1.000 29.77427 ? 122 PRO C CB  1 
ATOM   3264 C CG  . PRO C 1 122 ? -21.79835 -39.47655 -32.88807 1.000 27.87596 ? 122 PRO C CG  1 
ATOM   3265 C CD  . PRO C 1 122 ? -20.77829 -39.10029 -33.91408 1.000 24.36859 ? 122 PRO C CD  1 
ATOM   3266 N N   . GLY C 1 123 ? -19.79839 -43.68678 -33.39786 1.000 30.90317 ? 123 GLY C N   1 
ATOM   3267 C CA  . GLY C 1 123 ? -19.49884 -44.90344 -34.11557 1.000 31.12851 ? 123 GLY C CA  1 
ATOM   3268 C C   . GLY C 1 123 ? -18.03610 -45.09323 -34.46040 1.000 30.28867 ? 123 GLY C C   1 
ATOM   3269 O O   . GLY C 1 123 ? -17.62749 -46.21975 -34.76868 1.000 35.84658 ? 123 GLY C O   1 
ATOM   3270 N N   . HIS C 1 124 ? -17.23710 -44.02974 -34.40845 1.000 23.62966 ? 124 HIS C N   1 
ATOM   3271 C CA  . HIS C 1 124 ? -15.84070 -44.04992 -34.83425 1.000 25.75117 ? 124 HIS C CA  1 
ATOM   3272 C C   . HIS C 1 124 ? -14.88157 -44.02974 -33.65968 1.000 26.11732 ? 124 HIS C C   1 
ATOM   3273 O O   . HIS C 1 124 ? -13.70623 -43.68194 -33.82583 1.000 29.13592 ? 124 HIS C O   1 
ATOM   3274 C CB  . HIS C 1 124 ? -15.55800 -42.88367 -35.78315 1.000 30.83008 ? 124 HIS C CB  1 
ATOM   3275 C CG  . HIS C 1 124 ? -16.34667 -42.94545 -37.05350 1.000 32.57723 ? 124 HIS C CG  1 
ATOM   3276 N ND1 . HIS C 1 124 ? -17.71297 -43.12835 -37.07582 1.000 38.56699 ? 124 HIS C ND1 1 
ATOM   3277 C CD2 . HIS C 1 124 ? -15.95761 -42.86475 -38.34776 1.000 43.92568 ? 124 HIS C CD2 1 
ATOM   3278 C CE1 . HIS C 1 124 ? -18.13273 -43.15387 -38.32896 1.000 37.59208 ? 124 HIS C CE1 1 
ATOM   3279 N NE2 . HIS C 1 124 ? -17.08760 -42.99201 -39.12026 1.000 46.16055 ? 124 HIS C NE2 1 
ATOM   3280 N N   . GLU C 1 125 ? -15.37224 -44.40732 -32.47733 1.000 29.51683 ? 125 GLU C N   1 
ATOM   3281 C CA  . GLU C 1 125 ? -14.55667 -44.40084 -31.27044 1.000 29.98064 ? 125 GLU C CA  1 
ATOM   3282 C C   . GLU C 1 125 ? -13.39068 -45.37980 -31.35824 1.000 34.62893 ? 125 GLU C C   1 
ATOM   3283 O O   . GLU C 1 125 ? -12.34894 -45.15364 -30.73224 1.000 30.97791 ? 125 GLU C O   1 
ATOM   3284 C CB  . GLU C 1 125 ? -15.43771 -44.72414 -30.06528 1.000 27.93228 ? 125 GLU C CB  1 
ATOM   3285 C CG  . GLU C 1 125 ? -16.57526 -43.73717 -29.82517 1.000 27.56607 ? 125 GLU C CG  1 
ATOM   3286 C CD  . GLU C 1 125 ? -17.82999 -44.03408 -30.63872 1.000 30.94081 ? 125 GLU C CD  1 
ATOM   3287 O OE1 . GLU C 1 125 ? -17.94631 -45.14679 -31.19567 1.000 25.43306 ? 125 GLU C OE1 1 
ATOM   3288 O OE2 . GLU C 1 125 ? -18.71519 -43.15308 -30.69727 1.000 27.02084 ? 125 GLU C OE2 1 
ATOM   3289 N N   . GLY C 1 126 ? -13.54528 -46.46654 -32.11750 1.000 35.92104 ? 126 GLY C N   1 
ATOM   3290 C CA  . GLY C 1 126 ? -12.48771 -47.44903 -32.28585 1.000 37.50140 ? 126 GLY C CA  1 
ATOM   3291 C C   . GLY C 1 126 ? -11.22869 -46.90801 -32.93378 1.000 33.25799 ? 126 GLY C C   1 
ATOM   3292 O O   . GLY C 1 126 ? -10.14383 -46.97583 -32.34559 1.000 34.11785 ? 126 GLY C O   1 
ATOM   3293 N N   . GLU C 1 127 ? -11.35912 -46.37236 -34.14774 1.000 30.38589 ? 127 GLU C N   1 
ATOM   3294 C CA  . GLU C 1 127 ? -10.21449 -45.77671 -34.82957 1.000 37.03239 ? 127 GLU C CA  1 
ATOM   3295 C C   . GLU C 1 127 ? -9.59139  -44.68538 -33.97416 1.000 37.19825 ? 127 GLU C C   1 
ATOM   3296 O O   . GLU C 1 127 ? -8.37486  -44.65476 -33.75661 1.000 33.45449 ? 127 GLU C O   1 
ATOM   3297 C CB  . GLU C 1 127 ? -10.64959 -45.18539 -36.17232 1.000 42.33678 ? 127 GLU C CB  1 
ATOM   3298 C CG  . GLU C 1 127 ? -10.88335 -46.18697 -37.28495 1.000 55.64388 ? 127 GLU C CG  1 
ATOM   3299 C CD  . GLU C 1 127 ? -12.11092 -47.05637 -37.04868 1.000 61.66467 ? 127 GLU C CD  1 
ATOM   3300 O OE1 . GLU C 1 127 ? -12.97556 -46.66639 -36.22778 1.000 55.89888 ? 127 GLU C OE1 1 
ATOM   3301 O OE2 . GLU C 1 127 ? -12.20676 -48.13458 -37.67788 1.000 62.79784 ? 127 GLU C OE2 1 
ATOM   3302 N N   . TRP C 1 128 ? -10.42995 -43.77195 -33.49048 1.000 29.44841 ? 128 TRP C N   1 
ATOM   3303 C CA  . TRP C 1 128 ? -9.98349  -42.65402 -32.66811 1.000 25.46427 ? 128 TRP C CA  1 
ATOM   3304 C C   . TRP C 1 128 ? -9.15511  -43.12188 -31.47985 1.000 26.39210 ? 128 TRP C C   1 
ATOM   3305 O O   . TRP C 1 128 ? -8.08198  -42.57727 -31.19872 1.000 27.77691 ? 128 TRP C O   1 
ATOM   3306 C CB  . TRP C 1 128 ? -11.22082 -41.89674 -32.20109 1.000 24.19236 ? 128 TRP C CB  1 
ATOM   3307 C CG  . TRP C 1 128 ? -10.99489 -40.76878 -31.25341 1.000 21.75191 ? 128 TRP C CG  1 
ATOM   3308 C CD1 . TRP C 1 128 ? -10.64458 -39.49650 -31.56216 1.000 20.48796 ? 128 TRP C CD1 1 
ATOM   3309 C CD2 . TRP C 1 128 ? -11.15508 -40.81152 -29.83093 1.000 21.03096 ? 128 TRP C CD2 1 
ATOM   3310 N NE1 . TRP C 1 128 ? -10.56722 -38.73855 -30.42002 1.000 19.30821 ? 128 TRP C NE1 1 
ATOM   3311 C CE2 . TRP C 1 128 ? -10.87359 -39.52740 -29.34277 1.000 21.69348 ? 128 TRP C CE2 1 
ATOM   3312 C CE3 . TRP C 1 128 ? -11.49779 -41.81722 -28.92495 1.000 20.88801 ? 128 TRP C CE3 1 
ATOM   3313 C CZ2 . TRP C 1 128 ? -10.91997 -39.22154 -27.99102 1.000 19.51840 ? 128 TRP C CZ2 1 
ATOM   3314 C CZ3 . TRP C 1 128 ? -11.54403 -41.51112 -27.58808 1.000 26.06041 ? 128 TRP C CZ3 1 
ATOM   3315 C CH2 . TRP C 1 128 ? -11.26383 -40.22422 -27.13379 1.000 15.94956 ? 128 TRP C CH2 1 
ATOM   3316 N N   . PHE C 1 129 ? -9.65940  -44.11851 -30.75170 1.000 25.01580 ? 129 PHE C N   1 
ATOM   3317 C CA  . PHE C 1 129 ? -8.94537  -44.60428 -29.57884 1.000 29.67121 ? 129 PHE C CA  1 
ATOM   3318 C C   . PHE C 1 129 ? -7.59402  -45.18720 -29.97094 1.000 29.58181 ? 129 PHE C C   1 
ATOM   3319 O O   . PHE C 1 129 ? -6.58147  -44.94860 -29.30160 1.000 24.80924 ? 129 PHE C O   1 
ATOM   3320 C CB  . PHE C 1 129 ? -9.80289  -45.63711 -28.84938 1.000 25.74661 ? 129 PHE C CB  1 
ATOM   3321 C CG  . PHE C 1 129 ? -9.19182  -46.14820 -27.58311 1.000 29.36348 ? 129 PHE C CG  1 
ATOM   3322 C CD1 . PHE C 1 129 ? -9.18464  -45.37362 -26.43996 1.000 27.86697 ? 129 PHE C CD1 1 
ATOM   3323 C CD2 . PHE C 1 129 ? -8.63153  -47.41341 -27.53340 1.000 30.81119 ? 129 PHE C CD2 1 
ATOM   3324 C CE1 . PHE C 1 129 ? -8.62212  -45.84766 -25.26539 1.000 28.10593 ? 129 PHE C CE1 1 
ATOM   3325 C CE2 . PHE C 1 129 ? -8.06806  -47.89485 -26.36470 1.000 28.42854 ? 129 PHE C CE2 1 
ATOM   3326 C CZ  . PHE C 1 129 ? -8.06630  -47.11301 -25.22758 1.000 25.49061 ? 129 PHE C CZ  1 
ATOM   3327 N N   . ASP C 1 130 ? -7.55196  -45.91408 -31.08320 1.000 34.62201 ? 130 ASP C N   1 
ATOM   3328 C CA  . ASP C 1 130 ? -6.31966  -46.56628 -31.49834 1.000 34.41458 ? 130 ASP C CA  1 
ATOM   3329 C C   . ASP C 1 130 ? -5.24059  -45.56546 -31.89178 1.000 36.78353 ? 130 ASP C C   1 
ATOM   3330 O O   . ASP C 1 130 ? -4.05073  -45.88545 -31.79741 1.000 41.03840 ? 130 ASP C O   1 
ATOM   3331 C CB  . ASP C 1 130 ? -6.62041  -47.51896 -32.65588 1.000 32.54662 ? 130 ASP C CB  1 
ATOM   3332 C CG  . ASP C 1 130 ? -7.43070  -48.72478 -32.21562 1.000 35.28606 ? 130 ASP C CG  1 
ATOM   3333 O OD1 . ASP C 1 130 ? -7.55943  -48.94623 -30.98939 1.000 41.32823 ? 130 ASP C OD1 1 
ATOM   3334 O OD2 . ASP C 1 130 ? -7.95076  -49.44876 -33.09272 1.000 45.74461 ? 130 ASP C OD2 1 
ATOM   3335 N N   . ASN C 1 131 ? -5.61825  -44.36003 -32.30850 1.000 34.01739 ? 131 ASN C N   1 
ATOM   3336 C CA  . ASN C 1 131 ? -4.64402  -43.36183 -32.72290 1.000 31.07407 ? 131 ASN C CA  1 
ATOM   3337 C C   . ASN C 1 131 ? -4.20963  -42.43338 -31.59908 1.000 30.48209 ? 131 ASN C C   1 
ATOM   3338 O O   . ASN C 1 131 ? -3.34859  -41.57430 -31.82521 1.000 25.49777 ? 131 ASN C O   1 
ATOM   3339 C CB  . ASN C 1 131 ? -5.19372  -42.54539 -33.89462 1.000 34.55105 ? 131 ASN C CB  1 
ATOM   3340 C CG  . ASN C 1 131 ? -5.11481  -43.30462 -35.20389 1.000 46.97849 ? 131 ASN C CG  1 
ATOM   3341 O OD1 . ASN C 1 131 ? -6.04249  -44.02609 -35.57586 1.000 50.17635 ? 131 ASN C OD1 1 
ATOM   3342 N ND2 . ASN C 1 131 ? -3.98737  -43.17414 -35.89400 1.000 46.72397 ? 131 ASN C ND2 1 
ATOM   3343 N N   . LEU C 1 132 ? -4.77835  -42.57835 -30.40656 1.000 25.77847 ? 132 LEU C N   1 
ATOM   3344 C CA  . LEU C 1 132 ? -4.26611  -41.88316 -29.23647 1.000 26.45470 ? 132 LEU C CA  1 
ATOM   3345 C C   . LEU C 1 132 ? -2.90003  -42.44645 -28.84904 1.000 29.68658 ? 132 LEU C C   1 
ATOM   3346 O O   . LEU C 1 132 ? -2.52377  -43.55716 -29.23748 1.000 27.05763 ? 132 LEU C O   1 
ATOM   3347 C CB  . LEU C 1 132 ? -5.23555  -42.03285 -28.06637 1.000 25.14679 ? 132 LEU C CB  1 
ATOM   3348 C CG  . LEU C 1 132 ? -6.64261  -41.49885 -28.31755 1.000 26.97481 ? 132 LEU C CG  1 
ATOM   3349 C CD1 . LEU C 1 132 ? -7.54897  -41.85694 -27.15989 1.000 24.67547 ? 132 LEU C CD1 1 
ATOM   3350 C CD2 . LEU C 1 132 ? -6.61130  -39.99477 -28.51503 1.000 28.75710 ? 132 LEU C CD2 1 
ATOM   3351 N N   . SER C 1 133 ? -2.14950  -41.66814 -28.07639 1.000 27.25431 ? 133 SER C N   1 
ATOM   3352 C CA  . SER C 1 133 ? -0.89177  -42.19212 -27.56603 1.000 27.62819 ? 133 SER C CA  1 
ATOM   3353 C C   . SER C 1 133 ? -1.16044  -43.33674 -26.59457 1.000 27.93490 ? 133 SER C C   1 
ATOM   3354 O O   . SER C 1 133 ? -2.25350  -43.47584 -26.03643 1.000 21.31002 ? 133 SER C O   1 
ATOM   3355 C CB  . SER C 1 133 ? -0.07477  -41.09465 -26.88338 1.000 24.88726 ? 133 SER C CB  1 
ATOM   3356 O OG  . SER C 1 133 ? -0.55376  -40.79612 -25.58605 1.000 26.46713 ? 133 SER C OG  1 
ATOM   3357 N N   . SER C 1 134 ? -0.14671  -44.18489 -26.40799 1.000 26.66838 ? 134 SER C N   1 
ATOM   3358 C CA  . SER C 1 134 ? -0.30718  -45.29667 -25.47781 1.000 25.97525 ? 134 SER C CA  1 
ATOM   3359 C C   . SER C 1 134 ? -0.52195  -44.81035 -24.04750 1.000 20.97531 ? 134 SER C C   1 
ATOM   3360 O O   . SER C 1 134 ? -1.19055  -45.48511 -23.24845 1.000 20.89276 ? 134 SER C O   1 
ATOM   3361 C CB  . SER C 1 134 ? 0.90550   -46.22080 -25.57095 1.000 24.68445 ? 134 SER C CB  1 
ATOM   3362 O OG  . SER C 1 134 ? 2.05539   -45.57912 -25.04885 1.000 30.47190 ? 134 SER C OG  1 
ATOM   3363 N N   . ASP C 1 135 ? 0.01178   -43.63868 -23.70378 1.000 18.13755 ? 135 ASP C N   1 
ATOM   3364 C CA  . ASP C 1 135 ? -0.19645  -43.13802 -22.35632 1.000 18.70633 ? 135 ASP C CA  1 
ATOM   3365 C C   . ASP C 1 135 ? -1.61862  -42.63175 -22.19053 1.000 24.38341 ? 135 ASP C C   1 
ATOM   3366 O O   . ASP C 1 135 ? -2.20814  -42.73427 -21.10889 1.000 19.67431 ? 135 ASP C O   1 
ATOM   3367 C CB  . ASP C 1 135 ? 0.80322   -42.03605 -22.05928 1.000 21.59001 ? 135 ASP C CB  1 
ATOM   3368 C CG  . ASP C 1 135 ? 2.15385   -42.58919 -21.69195 1.000 26.70898 ? 135 ASP C CG  1 
ATOM   3369 O OD1 . ASP C 1 135 ? 2.18992   -43.69134 -21.12518 1.000 22.98351 ? 135 ASP C OD1 1 
ATOM   3370 O OD2 . ASP C 1 135 ? 3.17411   -41.91918 -21.95412 1.000 31.43263 ? 135 ASP C OD2 1 
ATOM   3371 N N   . GLU C 1 136 ? -2.18255  -42.10102 -23.26544 1.000 22.04136 ? 136 GLU C N   1 
ATOM   3372 C CA  . GLU C 1 136 ? -3.54180  -41.59205 -23.22441 1.000 19.86408 ? 136 GLU C CA  1 
ATOM   3373 C C   . GLU C 1 136 ? -4.53641  -42.74712 -23.14412 1.000 20.90063 ? 136 GLU C C   1 
ATOM   3374 O O   . GLU C 1 136 ? -5.48285  -42.70547 -22.35770 1.000 17.30266 ? 136 GLU C O   1 
ATOM   3375 C CB  . GLU C 1 136 ? -3.74988  -40.74566 -24.47425 1.000 23.77100 ? 136 GLU C CB  1 
ATOM   3376 C CG  . GLU C 1 136 ? -3.17408  -39.35582 -24.36342 1.000 27.68185 ? 136 GLU C CG  1 
ATOM   3377 C CD  . GLU C 1 136 ? -3.40821  -38.55922 -25.62442 1.000 29.66408 ? 136 GLU C CD  1 
ATOM   3378 O OE1 . GLU C 1 136 ? -2.90337  -38.98916 -26.69000 1.000 28.20538 ? 136 GLU C OE1 1 
ATOM   3379 O OE2 . GLU C 1 136 ? -4.08189  -37.51998 -25.56261 1.000 26.82158 ? 136 GLU C OE2 1 
ATOM   3380 N N   . ARG C 1 137 ? -4.29921  -43.81493 -23.91543 1.000 22.61383 ? 137 ARG C N   1 
ATOM   3381 C CA  . ARG C 1 137 ? -5.13765  -45.00853 -23.82327 1.000 20.76701 ? 137 ARG C CA  1 
ATOM   3382 C C   . ARG C 1 137 ? -5.07057  -45.62717 -22.43343 1.000 23.08443 ? 137 ARG C C   1 
ATOM   3383 O O   . ARG C 1 137 ? -6.10135  -46.00390 -21.86082 1.000 19.18971 ? 137 ARG C O   1 
ATOM   3384 C CB  . ARG C 1 137 ? -4.71808  -46.02496 -24.89461 1.000 21.41535 ? 137 ARG C CB  1 
ATOM   3385 C CG  . ARG C 1 137 ? -4.91543  -45.51649 -26.33524 1.000 28.17912 ? 137 ARG C CG  1 
ATOM   3386 C CD  . ARG C 1 137 ? -4.79422  -46.62281 -27.40051 1.000 32.00306 ? 137 ARG C CD  1 
ATOM   3387 N NE  . ARG C 1 137 ? -3.65886  -47.51088 -27.17753 1.000 27.79791 ? 137 ARG C NE  1 
ATOM   3388 C CZ  . ARG C 1 137 ? -2.44084  -47.31997 -27.66797 1.000 35.59094 ? 137 ARG C CZ  1 
ATOM   3389 N NH1 . ARG C 1 137 ? -2.17149  -46.31340 -28.48590 1.000 31.92852 ? 137 ARG C NH1 1 
ATOM   3390 N NH2 . ARG C 1 137 ? -1.46932  -48.17097 -27.34167 1.000 37.28990 ? 137 ARG C NH2 1 
ATOM   3391 N N   . ALA C 1 138 ? -3.86537  -45.73977 -21.86751 1.000 19.70362 ? 138 ALA C N   1 
ATOM   3392 C CA  . ALA C 1 138 ? -3.74842  -46.35171 -20.54880 1.000 24.12215 ? 138 ALA C CA  1 
ATOM   3393 C C   . ALA C 1 138 ? -4.51802  -45.55514 -19.49806 1.000 22.07729 ? 138 ALA C C   1 
ATOM   3394 O O   . ALA C 1 138 ? -5.15534  -46.13867 -18.61309 1.000 23.04122 ? 138 ALA C O   1 
ATOM   3395 C CB  . ALA C 1 138 ? -2.27487  -46.49518 -20.15583 1.000 24.14528 ? 138 ALA C CB  1 
ATOM   3396 N N   . PHE C 1 139 ? -4.46536  -44.22227 -19.56654 1.000 18.86446 ? 139 PHE C N   1 
ATOM   3397 C CA  . PHE C 1 139 ? -5.17283  -43.41803 -18.57102 1.000 20.16674 ? 139 PHE C CA  1 
ATOM   3398 C C   . PHE C 1 139 ? -6.67555  -43.62664 -18.66978 1.000 18.84229 ? 139 PHE C C   1 
ATOM   3399 O O   . PHE C 1 139 ? -7.35457  -43.83726 -17.65587 1.000 20.26372 ? 139 PHE C O   1 
ATOM   3400 C CB  . PHE C 1 139 ? -4.85412  -41.93689 -18.74505 1.000 18.72563 ? 139 PHE C CB  1 
ATOM   3401 C CG  . PHE C 1 139 ? -5.46105  -41.07077 -17.68888 1.000 21.87378 ? 139 PHE C CG  1 
ATOM   3402 C CD1 . PHE C 1 139 ? -5.05651  -41.17702 -16.36119 1.000 21.18563 ? 139 PHE C CD1 1 
ATOM   3403 C CD2 . PHE C 1 139 ? -6.47753  -40.19406 -18.00668 1.000 16.19003 ? 139 PHE C CD2 1 
ATOM   3404 C CE1 . PHE C 1 139 ? -5.62450  -40.38256 -15.38418 1.000 27.18323 ? 139 PHE C CE1 1 
ATOM   3405 C CE2 . PHE C 1 139 ? -7.05529  -39.39751 -17.03819 1.000 19.39689 ? 139 PHE C CE2 1 
ATOM   3406 C CZ  . PHE C 1 139 ? -6.62925  -39.48959 -15.72129 1.000 25.78117 ? 139 PHE C CZ  1 
ATOM   3407 N N   . MET C 1 140 ? -7.21114  -43.53659 -19.89055 1.000 18.71422 ? 140 MET C N   1 
ATOM   3408 C CA  . MET C 1 140 ? -8.63164  -43.79504 -20.12969 1.000 19.42599 ? 140 MET C CA  1 
ATOM   3409 C C   . MET C 1 140 ? -9.04873  -45.15636 -19.60729 1.000 22.54751 ? 140 MET C C   1 
ATOM   3410 O O   . MET C 1 140 ? -10.09315 -45.29173 -18.95698 1.000 20.15641 ? 140 MET C O   1 
ATOM   3411 C CB  . MET C 1 140 ? -8.91714  -43.72001 -21.62370 1.000 19.54134 ? 140 MET C CB  1 
ATOM   3412 C CG  . MET C 1 140 ? -8.82017  -42.35148 -22.17370 1.000 25.65778 ? 140 MET C CG  1 
ATOM   3413 S SD  . MET C 1 140 ? -9.33888  -42.31327 -23.88624 1.000 24.01002 ? 140 MET C SD  1 
ATOM   3414 C CE  . MET C 1 140 ? -8.84757  -40.63795 -24.25836 1.000 27.36445 ? 140 MET C CE  1 
ATOM   3415 N N   . GLU C 1 141 ? -8.24045  -46.18081 -19.89169 1.000 23.72720 ? 141 GLU C N   1 
ATOM   3416 C CA  . GLU C 1 141 ? -8.59684  -47.56358 -19.60323 1.000 23.74119 ? 141 GLU C CA  1 
ATOM   3417 C C   . GLU C 1 141 ? -8.74405  -47.83609 -18.11284 1.000 26.67796 ? 141 GLU C C   1 
ATOM   3418 O O   . GLU C 1 141 ? -9.41121  -48.80521 -17.73747 1.000 32.50445 ? 141 GLU C O   1 
ATOM   3419 C CB  . GLU C 1 141 ? -7.52727  -48.49070 -20.18869 1.000 31.13518 ? 141 GLU C CB  1 
ATOM   3420 C CG  . GLU C 1 141 ? -7.93621  -49.16747 -21.48225 1.000 34.31845 ? 141 GLU C CG  1 
ATOM   3421 C CD  . GLU C 1 141 ? -6.73442  -49.68602 -22.25742 1.000 34.61425 ? 141 GLU C CD  1 
ATOM   3422 O OE1 . GLU C 1 141 ? -5.67822  -49.92524 -21.62956 1.000 38.15464 ? 141 GLU C OE1 1 
ATOM   3423 O OE2 . GLU C 1 141 ? -6.85297  -49.84448 -23.49067 1.000 40.98738 ? 141 GLU C OE2 1 
ATOM   3424 N N   . THR C 1 142 ? -8.13159  -47.02282 -17.25030 1.000 26.84985 ? 142 THR C N   1 
ATOM   3425 C CA  . THR C 1 142 ? -8.34063  -47.22018 -15.81962 1.000 26.21412 ? 142 THR C CA  1 
ATOM   3426 C C   . THR C 1 142 ? -9.76516  -46.87758 -15.38905 1.000 32.67456 ? 142 THR C C   1 
ATOM   3427 O O   . THR C 1 142 ? -10.21145 -47.34191 -14.33565 1.000 30.82135 ? 142 THR C O   1 
ATOM   3428 C CB  . THR C 1 142 ? -7.33055  -46.40616 -15.00719 1.000 27.82149 ? 142 THR C CB  1 
ATOM   3429 O OG1 . THR C 1 142 ? -7.72886  -45.02797 -14.95274 1.000 37.62545 ? 142 THR C OG1 1 
ATOM   3430 C CG2 . THR C 1 142 ? -5.90399  -46.52706 -15.58096 1.000 24.99532 ? 142 THR C CG2 1 
ATOM   3431 N N   . ASN C 1 143 ? -10.49693 -46.10213 -16.18293 1.000 26.40135 ? 143 ASN C N   1 
ATOM   3432 C CA  . ASN C 1 143 ? -11.86404 -45.71041 -15.82668 1.000 26.34437 ? 143 ASN C CA  1 
ATOM   3433 C C   . ASN C 1 143 ? -12.89431 -46.69279 -16.39690 1.000 29.14339 ? 143 ASN C C   1 
ATOM   3434 O O   . ASN C 1 143 ? -13.77774 -46.34052 -17.18280 1.000 22.44114 ? 143 ASN C O   1 
ATOM   3435 C CB  . ASN C 1 143 ? -12.13091 -44.28933 -16.29523 1.000 19.34630 ? 143 ASN C CB  1 
ATOM   3436 C CG  . ASN C 1 143 ? -11.36983 -43.26900 -15.48055 1.000 22.62636 ? 143 ASN C CG  1 
ATOM   3437 O OD1 . ASN C 1 143 ? -11.10769 -43.47864 -14.28906 1.000 24.37586 ? 143 ASN C OD1 1 
ATOM   3438 N ND2 . ASN C 1 143 ? -10.96516 -42.18109 -16.12315 1.000 24.43467 ? 143 ASN C ND2 1 
ATOM   3439 N N   . VAL C 1 144 ? -12.76076 -47.95421 -15.98301 1.000 31.89529 ? 144 VAL C N   1 
ATOM   3440 C CA  . VAL C 1 144 ? -13.69331 -49.02158 -16.34108 1.000 31.59320 ? 144 VAL C CA  1 
ATOM   3441 C C   . VAL C 1 144 ? -14.05736 -49.79544 -15.08143 1.000 33.50792 ? 144 VAL C C   1 
ATOM   3442 O O   . VAL C 1 144 ? -13.17260 -50.23672 -14.33948 1.000 36.03230 ? 144 VAL C O   1 
ATOM   3443 C CB  . VAL C 1 144 ? -13.11348 -49.97171 -17.40884 1.000 33.00877 ? 144 VAL C CB  1 
ATOM   3444 C CG1 . VAL C 1 144 ? -14.22044 -50.77970 -18.02877 1.000 35.63105 ? 144 VAL C CG1 1 
ATOM   3445 C CG2 . VAL C 1 144 ? -12.41749 -49.18196 -18.49286 1.000 31.18812 ? 144 VAL C CG2 1 
ATOM   3446 N N   . ASP C 1 145 ? -15.35527 -49.96320 -14.85267 1.000 36.86285 ? 145 ASP C N   1 
ATOM   3447 C CA  . ASP C 1 145 ? -15.88804 -50.57378 -13.64041 1.000 38.63342 ? 145 ASP C CA  1 
ATOM   3448 C C   . ASP C 1 145 ? -16.23349 -52.04134 -13.86847 1.000 43.63207 ? 145 ASP C C   1 
ATOM   3449 O O   . ASP C 1 145 ? -15.48152 -52.92934 -13.46234 1.000 51.36819 ? 145 ASP C O   1 
ATOM   3450 C CB  . ASP C 1 145 ? -17.11935 -49.79384 -13.16864 1.000 28.74018 ? 145 ASP C CB  1 
ATOM   3451 C CG  . ASP C 1 145 ? -17.54947 -50.15723 -11.75543 1.000 33.27569 ? 145 ASP C CG  1 
ATOM   3452 O OD1 . ASP C 1 145 ? -16.82333 -49.83428 -10.79294 1.000 38.13831 ? 145 ASP C OD1 1 
ATOM   3453 O OD2 . ASP C 1 145 ? -18.64715 -50.72978 -11.60578 1.000 45.79233 ? 145 ASP C OD2 1 
HETATM 3454 P P   . PO4 D 2 .   ? -20.48212 -15.64996 -26.95102 1.000 18.97813 ? 201 PO4 A P   1 
HETATM 3455 O O1  . PO4 D 2 .   ? -19.33629 -14.67586 -27.20696 1.000 17.27107 ? 201 PO4 A O1  1 
HETATM 3456 O O2  . PO4 D 2 .   ? -19.89694 -16.83826 -26.26229 1.000 20.33631 ? 201 PO4 A O2  1 
HETATM 3457 O O3  . PO4 D 2 .   ? -21.03633 -16.13557 -28.24770 1.000 20.10391 ? 201 PO4 A O3  1 
HETATM 3458 O O4  . PO4 D 2 .   ? -21.57603 -14.96508 -26.15517 1.000 18.73123 ? 201 PO4 A O4  1 
HETATM 3459 P P   . PO4 E 2 .   ? -41.24011 -26.20560 -22.88897 1.000 29.17376 ? 201 PO4 B P   1 
HETATM 3460 O O1  . PO4 E 2 .   ? -41.06391 -26.20090 -24.35857 1.000 26.40413 ? 201 PO4 B O1  1 
HETATM 3461 O O2  . PO4 E 2 .   ? -42.63512 -25.72872 -22.53963 1.000 23.14237 ? 201 PO4 B O2  1 
HETATM 3462 O O3  . PO4 E 2 .   ? -41.01065 -27.60873 -22.35945 1.000 29.46686 ? 201 PO4 B O3  1 
HETATM 3463 O O4  . PO4 E 2 .   ? -40.22120 -25.27817 -22.27404 1.000 30.09121 ? 201 PO4 B O4  1 
HETATM 3464 P P   . PO4 F 2 .   ? -21.83445 -39.31611 -26.94460 1.000 26.55456 ? 201 PO4 C P   1 
HETATM 3465 O O1  . PO4 F 2 .   ? -20.59109 -38.50272 -26.61065 1.000 25.33802 ? 201 PO4 C O1  1 
HETATM 3466 O O2  . PO4 F 2 .   ? -22.40067 -38.93687 -28.25877 1.000 24.82717 ? 201 PO4 C O2  1 
HETATM 3467 O O3  . PO4 F 2 .   ? -21.54323 -40.80544 -26.99557 1.000 22.93156 ? 201 PO4 C O3  1 
HETATM 3468 O O4  . PO4 F 2 .   ? -22.88164 -39.07963 -25.88126 1.000 29.20410 ? 201 PO4 C O4  1 
HETATM 3469 O O   . HOH G 3 .   ? -20.56135 -4.01476  -36.06040 1.000 39.68248 ? 301 HOH A O   1 
HETATM 3470 O O   . HOH G 3 .   ? -29.69167 0.79079   -24.01375 1.000 28.52853 ? 302 HOH A O   1 
HETATM 3471 O O   . HOH G 3 .   ? -17.57376 -12.38894 -31.18724 1.000 23.07665 ? 303 HOH A O   1 
HETATM 3472 O O   . HOH G 3 .   ? -12.81562 -20.29101 -3.35020  1.000 35.70956 ? 304 HOH A O   1 
HETATM 3473 O O   . HOH G 3 .   ? -10.11180 -8.70890  -10.24876 1.000 35.69319 ? 305 HOH A O   1 
HETATM 3474 O O   . HOH G 3 .   ? -5.86674  -17.48048 -21.77695 1.000 21.20731 ? 306 HOH A O   1 
HETATM 3475 O O   . HOH G 3 .   ? -18.85735 -24.72516 -2.62427  1.000 28.89371 ? 307 HOH A O   1 
HETATM 3476 O O   . HOH G 3 .   ? -30.86575 -23.02438 -33.36989 1.000 39.89093 ? 308 HOH A O   1 
HETATM 3477 O O   . HOH G 3 .   ? -23.41044 -25.76985 -34.02443 1.000 32.31793 ? 309 HOH A O   1 
HETATM 3478 O O   . HOH G 3 .   ? -15.91851 -22.92052 -2.16354  1.000 33.00898 ? 310 HOH A O   1 
HETATM 3479 O O   . HOH G 3 .   ? -30.15826 -10.28537 -30.71970 1.000 25.98945 ? 311 HOH A O   1 
HETATM 3480 O O   . HOH G 3 .   ? -12.03157 -30.76742 -9.49191  1.000 17.62957 ? 312 HOH A O   1 
HETATM 3481 O O   . HOH G 3 .   ? -21.24623 -19.87882 -9.04708  1.000 21.50400 ? 313 HOH A O   1 
HETATM 3482 O O   . HOH G 3 .   ? -31.57648 0.51931   -21.06245 1.000 35.15714 ? 314 HOH A O   1 
HETATM 3483 O O   . HOH G 3 .   ? -13.13323 -34.03000 -9.42402  1.000 29.52828 ? 315 HOH A O   1 
HETATM 3484 O O   . HOH G 3 .   ? -34.15176 -5.69180  -19.24114 1.000 26.86324 ? 316 HOH A O   1 
HETATM 3485 O O   . HOH G 3 .   ? -6.43529  -31.74424 -28.05195 1.000 23.72452 ? 317 HOH A O   1 
HETATM 3486 O O   . HOH G 3 .   ? -20.80781 -20.17524 -32.40299 1.000 13.52388 ? 318 HOH A O   1 
HETATM 3487 O O   . HOH G 3 .   ? -7.76167  -9.98575  -18.46206 1.000 36.29059 ? 319 HOH A O   1 
HETATM 3488 O O   . HOH G 3 .   ? -9.53313  -40.35089 -14.39650 1.000 26.81990 ? 320 HOH A O   1 
HETATM 3489 O O   . HOH G 3 .   ? -24.34915 -27.19933 -17.61739 1.000 27.29346 ? 321 HOH A O   1 
HETATM 3490 O O   . HOH G 3 .   ? -26.618   9.689     -19.492   1.000 31.72438 ? 322 HOH A O   1 
HETATM 3491 O O   . HOH G 3 .   ? -13.79326 -18.27562 -38.10067 1.000 27.04205 ? 323 HOH A O   1 
HETATM 3492 O O   . HOH G 3 .   ? -23.07728 -21.69779 -34.95351 1.000 21.31766 ? 324 HOH A O   1 
HETATM 3493 O O   . HOH G 3 .   ? -24.05035 2.01380   -13.65684 1.000 24.70821 ? 325 HOH A O   1 
HETATM 3494 O O   . HOH G 3 .   ? -17.65090 2.28778   -14.62056 1.000 30.71200 ? 326 HOH A O   1 
HETATM 3495 O O   . HOH G 3 .   ? -9.77188  -37.44343 -14.86742 1.000 24.46061 ? 327 HOH A O   1 
HETATM 3496 O O   . HOH G 3 .   ? -26.52949 -15.98850 -32.94532 1.000 15.24121 ? 328 HOH A O   1 
HETATM 3497 O O   . HOH G 3 .   ? -27.37351 -1.95882  -27.76792 1.000 22.65237 ? 329 HOH A O   1 
HETATM 3498 O O   . HOH G 3 .   ? -9.64950  -15.45115 -33.80872 1.000 34.44318 ? 330 HOH A O   1 
HETATM 3499 O O   . HOH G 3 .   ? -3.46334  -23.01808 -9.47213  1.000 24.62878 ? 331 HOH A O   1 
HETATM 3500 O O   . HOH G 3 .   ? -16.49109 -33.70665 -7.39565  1.000 24.18774 ? 332 HOH A O   1 
HETATM 3501 O O   . HOH G 3 .   ? -34.29155 -17.02182 -30.94767 1.000 15.01653 ? 333 HOH A O   1 
HETATM 3502 O O   . HOH G 3 .   ? -5.03080  -15.46201 -9.27668  1.000 32.92379 ? 334 HOH A O   1 
HETATM 3503 O O   . HOH G 3 .   ? -14.38220 -25.80043 2.07659   1.000 22.62156 ? 335 HOH A O   1 
HETATM 3504 O O   . HOH G 3 .   ? -1.02586  -22.31216 -21.97976 1.000 30.58822 ? 336 HOH A O   1 
HETATM 3505 O O   . HOH G 3 .   ? -4.91207  -17.35907 -28.96197 1.000 28.65960 ? 337 HOH A O   1 
HETATM 3506 O O   . HOH G 3 .   ? -12.61995 -32.31503 -2.92238  1.000 32.84991 ? 338 HOH A O   1 
HETATM 3507 O O   . HOH G 3 .   ? -2.19092  -29.11331 -8.71408  1.000 34.34823 ? 339 HOH A O   1 
HETATM 3508 O O   . HOH G 3 .   ? -6.10542  -28.84852 -31.21042 1.000 27.88091 ? 340 HOH A O   1 
HETATM 3509 O O   . HOH G 3 .   ? -3.33225  -33.05086 -12.64162 1.000 23.75379 ? 341 HOH A O   1 
HETATM 3510 O O   . HOH G 3 .   ? -15.18745 -36.59421 -7.84219  1.000 19.79270 ? 342 HOH A O   1 
HETATM 3511 O O   . HOH G 3 .   ? -20.79538 5.18377   -19.41968 1.000 17.59431 ? 343 HOH A O   1 
HETATM 3512 O O   . HOH G 3 .   ? -15.40005 -26.94364 -33.50357 1.000 17.04658 ? 344 HOH A O   1 
HETATM 3513 O O   . HOH G 3 .   ? -1.18081  -34.89103 -20.37791 1.000 35.73963 ? 345 HOH A O   1 
HETATM 3514 O O   . HOH G 3 .   ? -26.40628 -8.05329  -34.02953 1.000 24.43134 ? 346 HOH A O   1 
HETATM 3515 O O   . HOH G 3 .   ? -5.80621  -23.00771 -29.87055 1.000 24.43522 ? 347 HOH A O   1 
HETATM 3516 O O   . HOH G 3 .   ? -24.70763 -14.46216 -36.52405 1.000 27.37098 ? 348 HOH A O   1 
HETATM 3517 O O   . HOH G 3 .   ? -25.523   5.387     -26.481   1.000 30.05049 ? 349 HOH A O   1 
HETATM 3518 O O   . HOH G 3 .   ? -20.25940 -25.06811 -36.55969 1.000 22.27289 ? 350 HOH A O   1 
HETATM 3519 O O   . HOH G 3 .   ? -10.56592 -36.97197 -17.44116 1.000 14.85854 ? 351 HOH A O   1 
HETATM 3520 O O   . HOH G 3 .   ? -16.44834 -31.79470 -11.82921 1.000 18.81981 ? 352 HOH A O   1 
HETATM 3521 O O   . HOH G 3 .   ? -19.58599 -14.93856 -37.38733 1.000 12.39072 ? 353 HOH A O   1 
HETATM 3522 O O   . HOH G 3 .   ? -33.54477 -16.48526 -33.55699 1.000 27.67138 ? 354 HOH A O   1 
HETATM 3523 O O   . HOH G 3 .   ? -6.35568  -26.48214 -3.95168  1.000 28.42523 ? 355 HOH A O   1 
HETATM 3524 O O   . HOH G 3 .   ? -24.34253 -15.72885 -12.17969 1.000 22.24765 ? 356 HOH A O   1 
HETATM 3525 O O   . HOH G 3 .   ? -6.75476  -17.87962 -2.63023  1.000 21.19974 ? 357 HOH A O   1 
HETATM 3526 O O   . HOH G 3 .   ? -34.80215 -11.35133 -29.21600 1.000 17.34838 ? 358 HOH A O   1 
HETATM 3527 O O   . HOH G 3 .   ? -17.69547 -5.16467  -32.84678 1.000 32.39884 ? 359 HOH A O   1 
HETATM 3528 O O   . HOH G 3 .   ? -16.50532 -2.04683  -26.28887 1.000 28.35897 ? 360 HOH A O   1 
HETATM 3529 O O   . HOH G 3 .   ? -9.62346  -40.31955 -9.56675  1.000 30.97124 ? 361 HOH A O   1 
HETATM 3530 O O   . HOH G 3 .   ? -12.78792 -25.81225 -6.18990  1.000 20.02293 ? 362 HOH A O   1 
HETATM 3531 O O   . HOH G 3 .   ? -23.946   5.774     -12.945   1.000 25.22435 ? 363 HOH A O   1 
HETATM 3532 O O   . HOH G 3 .   ? -18.86756 4.50791   -22.01214 1.000 34.67545 ? 364 HOH A O   1 
HETATM 3533 O O   . HOH G 3 .   ? -13.60384 -40.23181 -4.45238  1.000 29.15501 ? 365 HOH A O   1 
HETATM 3534 O O   . HOH G 3 .   ? -27.03086 -3.64855  -19.46088 1.000 23.69583 ? 366 HOH A O   1 
HETATM 3535 O O   . HOH G 3 .   ? -0.97621  -31.32510 -19.10417 1.000 31.56296 ? 367 HOH A O   1 
HETATM 3536 O O   . HOH G 3 .   ? -14.92922 -12.07018 -23.57000 1.000 20.96427 ? 368 HOH A O   1 
HETATM 3537 O O   . HOH G 3 .   ? -19.08024 -37.38700 -2.66209  1.000 26.59284 ? 369 HOH A O   1 
HETATM 3538 O O   . HOH G 3 .   ? -8.98465  -37.00823 -9.48700  1.000 29.91951 ? 370 HOH A O   1 
HETATM 3539 O O   . HOH G 3 .   ? -15.94153 -46.44852 -7.97407  1.000 30.10398 ? 371 HOH A O   1 
HETATM 3540 O O   . HOH G 3 .   ? -24.79763 -27.79882 -24.69978 1.000 21.34457 ? 372 HOH A O   1 
HETATM 3541 O O   . HOH G 3 .   ? -17.29471 -0.18959  -28.11561 1.000 33.91570 ? 373 HOH A O   1 
HETATM 3542 O O   . HOH G 3 .   ? -4.73861  -16.55897 -15.42766 1.000 24.85205 ? 374 HOH A O   1 
HETATM 3543 O O   . HOH G 3 .   ? -29.98850 -15.75984 -36.01775 0.50  30.94856 ? 375 HOH A O   1 
HETATM 3544 O O   . HOH G 3 .   ? -8.10080  -36.19386 -5.26994  1.000 32.91051 ? 376 HOH A O   1 
HETATM 3545 O O   . HOH G 3 .   ? -30.29643 -3.63910  -18.42410 1.000 26.07080 ? 377 HOH A O   1 
HETATM 3546 O O   . HOH G 3 .   ? -15.89074 -17.76149 -36.52061 1.000 15.58623 ? 378 HOH A O   1 
HETATM 3547 O O   . HOH G 3 .   ? -21.46902 5.47924   -26.51958 1.000 25.44008 ? 379 HOH A O   1 
HETATM 3548 O O   . HOH G 3 .   ? -20.64759 2.46556   -32.82104 1.000 37.76537 ? 380 HOH A O   1 
HETATM 3549 O O   . HOH G 3 .   ? -17.78644 -5.79762  -9.97711  1.000 33.35843 ? 381 HOH A O   1 
HETATM 3550 O O   . HOH G 3 .   ? -16.51698 -14.14270 -33.52648 1.000 29.18385 ? 382 HOH A O   1 
HETATM 3551 O O   . HOH G 3 .   ? -9.56291  -25.84043 -34.90917 1.000 26.94123 ? 383 HOH A O   1 
HETATM 3552 O O   . HOH G 3 .   ? -32.22366 -5.78519  -25.08961 1.000 20.50952 ? 384 HOH A O   1 
HETATM 3553 O O   . HOH G 3 .   ? -18.72824 -19.92970 -30.58867 1.000 15.60282 ? 385 HOH A O   1 
HETATM 3554 O O   . HOH G 3 .   ? -2.46628  -18.57967 -24.46018 1.000 36.76600 ? 386 HOH A O   1 
HETATM 3555 O O   . HOH G 3 .   ? -25.30097 -2.88974  -17.47711 1.000 23.06292 ? 387 HOH A O   1 
HETATM 3556 O O   . HOH G 3 .   ? -2.56069  -20.04854 -10.95213 1.000 32.00610 ? 388 HOH A O   1 
HETATM 3557 O O   . HOH G 3 .   ? -10.35542 -42.74376 -9.57565  1.000 30.58215 ? 389 HOH A O   1 
HETATM 3558 O O   . HOH G 3 .   ? -7.20702  -11.49120 -24.22303 1.000 32.94238 ? 390 HOH A O   1 
HETATM 3559 O O   . HOH G 3 .   ? -4.90940  -13.35516 -27.31838 1.000 38.53692 ? 391 HOH A O   1 
HETATM 3560 O O   . HOH G 3 .   ? -4.60916  -15.72221 -19.62398 1.000 34.50994 ? 392 HOH A O   1 
HETATM 3561 O O   . HOH G 3 .   ? -5.89552  -24.27690 -5.92097  1.000 20.50031 ? 393 HOH A O   1 
HETATM 3562 O O   . HOH G 3 .   ? -14.64040 -32.94297 -0.70158  1.000 32.71795 ? 394 HOH A O   1 
HETATM 3563 O O   . HOH G 3 .   ? -0.12242  -28.09152 -15.27974 1.000 32.63666 ? 395 HOH A O   1 
HETATM 3564 O O   . HOH G 3 .   ? -9.98859  -11.73420 -17.68665 1.000 24.31209 ? 396 HOH A O   1 
HETATM 3565 O O   . HOH G 3 .   ? -19.36720 -3.77433  -33.94174 1.000 31.70229 ? 397 HOH A O   1 
HETATM 3566 O O   . HOH G 3 .   ? -6.58497  -10.19688 -22.48729 1.000 35.65694 ? 398 HOH A O   1 
HETATM 3567 O O   . HOH G 3 .   ? -28.49150 -17.31456 -34.97834 1.000 30.35517 ? 399 HOH A O   1 
HETATM 3568 O O   . HOH G 3 .   ? -13.85828 -14.45619 -34.27689 1.000 31.73326 ? 400 HOH A O   1 
HETATM 3569 O O   . HOH G 3 .   ? -29.04712 -3.65244  -27.85515 1.000 39.97444 ? 401 HOH A O   1 
HETATM 3570 O O   . HOH G 3 .   ? -3.00978  -26.85720 -7.50859  1.000 29.60608 ? 402 HOH A O   1 
HETATM 3571 O O   . HOH G 3 .   ? -4.88298  -24.89326 -8.14938  1.000 24.05070 ? 403 HOH A O   1 
HETATM 3572 O O   . HOH G 3 .   ? -29.59420 -6.68888  -29.40649 1.000 29.84672 ? 404 HOH A O   1 
HETATM 3573 O O   . HOH G 3 .   ? -18.11416 -40.74877 -1.14306  1.000 41.26957 ? 405 HOH A O   1 
HETATM 3574 O O   . HOH G 3 .   ? -0.82335  -31.81232 -11.29245 1.000 47.24329 ? 406 HOH A O   1 
HETATM 3575 O O   . HOH G 3 .   ? -6.277    -32.968   -6.323    1.000 28.99425 ? 407 HOH A O   1 
HETATM 3576 O O   . HOH G 3 .   ? -17.45507 -46.16838 -5.78927  1.000 36.98685 ? 408 HOH A O   1 
HETATM 3577 O O   . HOH G 3 .   ? -12.012   -20.692   -40.776   1.000 34.64359 ? 409 HOH A O   1 
HETATM 3578 O O   . HOH G 3 .   ? -3.71214  -23.25151 -5.17383  1.000 35.39274 ? 410 HOH A O   1 
HETATM 3579 O O   . HOH G 3 .   ? -4.99625  -9.67383  -20.63425 1.000 43.28383 ? 411 HOH A O   1 
HETATM 3580 O O   . HOH G 3 .   ? -21.87668 -13.00147 -36.67660 1.000 29.90082 ? 412 HOH A O   1 
HETATM 3581 O O   . HOH G 3 .   ? -17.61538 -32.12914 -9.36886  1.000 21.48644 ? 413 HOH A O   1 
HETATM 3582 O O   . HOH G 3 .   ? -4.711    -28.037   -5.238    1.000 29.11534 ? 414 HOH A O   1 
HETATM 3583 O O   . HOH G 3 .   ? -32.95508 -1.85584  -20.99797 1.000 39.32007 ? 415 HOH A O   1 
HETATM 3584 O O   . HOH G 3 .   ? -4.175    -30.782   -6.241    1.000 37.76101 ? 416 HOH A O   1 
HETATM 3585 O O   . HOH G 3 .   ? -30.432   5.477     -17.258   1.000 41.40053 ? 417 HOH A O   1 
HETATM 3586 O O   . HOH G 3 .   ? -21.61920 1.35979   -12.28919 1.000 31.11112 ? 418 HOH A O   1 
HETATM 3587 O O   . HOH G 3 .   ? -26.30754 -25.11991 -25.28222 1.000 25.50452 ? 419 HOH A O   1 
HETATM 3588 O O   . HOH G 3 .   ? -3.23110  -19.57143 -8.75308  1.000 33.34179 ? 420 HOH A O   1 
HETATM 3589 O O   . HOH G 3 .   ? -2.04807  -17.25671 -26.17970 1.000 38.72902 ? 421 HOH A O   1 
HETATM 3590 O O   . HOH G 3 .   ? -28.14349 -23.43955 -36.55577 1.000 38.04007 ? 422 HOH A O   1 
HETATM 3591 O O   . HOH G 3 .   ? -4.16795  -16.53880 -2.57042  1.000 32.29236 ? 423 HOH A O   1 
HETATM 3592 O O   . HOH G 3 .   ? -32.00917 0.76034   -18.49650 1.000 30.83279 ? 424 HOH A O   1 
HETATM 3593 O O   . HOH G 3 .   ? -0.36497  -20.42464 -19.99796 1.000 39.78524 ? 425 HOH A O   1 
HETATM 3594 O O   . HOH G 3 .   ? -7.07093  -9.89584  -26.42153 1.000 35.77647 ? 426 HOH A O   1 
HETATM 3595 O O   . HOH G 3 .   ? -9.85413  -28.04415 -33.73903 1.000 32.81052 ? 427 HOH A O   1 
HETATM 3596 O O   . HOH G 3 .   ? -15.85657 -19.93388 -1.18979  1.000 34.33692 ? 428 HOH A O   1 
HETATM 3597 O O   . HOH G 3 .   ? -25.47954 -22.62217 -36.57707 1.000 36.16166 ? 429 HOH A O   1 
HETATM 3598 O O   . HOH G 3 .   ? -14.093   -21.841   -41.807   1.000 29.41499 ? 430 HOH A O   1 
HETATM 3599 O O   . HOH G 3 .   ? -36.074   -12.545   -33.785   1.000 32.00901 ? 431 HOH A O   1 
HETATM 3600 O O   . HOH G 3 .   ? -7.08529  -37.97655 -8.19966  1.000 36.45063 ? 432 HOH A O   1 
HETATM 3601 O O   . HOH G 3 .   ? -16.93587 -21.85974 0.51857   1.000 30.98056 ? 433 HOH A O   1 
HETATM 3602 O O   . HOH G 3 .   ? -3.75991  -15.42121 -13.40201 1.000 36.92198 ? 434 HOH A O   1 
HETATM 3603 O O   . HOH G 3 .   ? -32.69930 -9.55505  -30.15129 1.000 24.39851 ? 435 HOH A O   1 
HETATM 3604 O O   . HOH G 3 .   ? -16.17039 -40.75224 0.13472   1.000 43.49992 ? 436 HOH A O   1 
HETATM 3605 O O   . HOH G 3 .   ? -32.13155 -7.34171  -29.59517 1.000 34.83814 ? 437 HOH A O   1 
HETATM 3606 O O   . HOH H 3 .   ? -38.69478 -17.28299 4.01656   1.000 25.25557 ? 301 HOH B O   1 
HETATM 3607 O O   . HOH H 3 .   ? -26.94660 -24.39863 -0.60422  1.000 33.15146 ? 302 HOH B O   1 
HETATM 3608 O O   . HOH H 3 .   ? -57.99472 -34.70324 -24.92844 1.000 38.70216 ? 303 HOH B O   1 
HETATM 3609 O O   . HOH H 3 .   ? -44.36066 -13.77097 -14.01206 1.000 20.96984 ? 304 HOH B O   1 
HETATM 3610 O O   . HOH H 3 .   ? -31.90331 -27.98463 -6.92577  1.000 22.24508 ? 305 HOH B O   1 
HETATM 3611 O O   . HOH H 3 .   ? -46.01365 -20.49204 -7.39583  1.000 34.83405 ? 306 HOH B O   1 
HETATM 3612 O O   . HOH H 3 .   ? -48.31921 -44.83339 -17.65391 1.000 30.41444 ? 307 HOH B O   1 
HETATM 3613 O O   . HOH H 3 .   ? -25.69475 -5.48118  -5.43999  1.000 39.84603 ? 308 HOH B O   1 
HETATM 3614 O O   . HOH H 3 .   ? -32.09255 -30.40430 -32.67539 1.000 31.89956 ? 309 HOH B O   1 
HETATM 3615 O O   . HOH H 3 .   ? -23.87344 -14.08080 -7.08617  1.000 28.01725 ? 310 HOH B O   1 
HETATM 3616 O O   . HOH H 3 .   ? -37.40219 -13.09092 2.17064   1.000 32.95926 ? 311 HOH B O   1 
HETATM 3617 O O   . HOH H 3 .   ? -49.86701 -42.91006 -20.89102 1.000 30.45730 ? 312 HOH B O   1 
HETATM 3618 O O   . HOH H 3 .   ? -38.50891 -21.77901 -0.81250  1.000 27.86746 ? 313 HOH B O   1 
HETATM 3619 O O   . HOH H 3 .   ? -41.88779 -24.21911 -10.85529 1.000 16.32068 ? 314 HOH B O   1 
HETATM 3620 O O   . HOH H 3 .   ? -51.12162 -40.17261 -8.08667  1.000 32.21101 ? 315 HOH B O   1 
HETATM 3621 O O   . HOH H 3 .   ? -33.62185 -21.49063 1.01076   1.000 26.50596 ? 316 HOH B O   1 
HETATM 3622 O O   . HOH H 3 .   ? -39.90564 -5.03432  -20.31400 1.000 39.80001 ? 317 HOH B O   1 
HETATM 3623 O O   . HOH H 3 .   ? -33.56446 -22.50901 -32.21656 1.000 28.50637 ? 318 HOH B O   1 
HETATM 3624 O O   . HOH H 3 .   ? -42.42252 -36.86363 -28.06850 1.000 30.00698 ? 319 HOH B O   1 
HETATM 3625 O O   . HOH H 3 .   ? -21.24895 -6.89959  -11.85882 1.000 24.31998 ? 320 HOH B O   1 
HETATM 3626 O O   . HOH H 3 .   ? -46.41109 -39.28075 -15.23961 1.000 28.22912 ? 321 HOH B O   1 
HETATM 3627 O O   . HOH H 3 .   ? -54.09207 -34.36803 -7.57079  1.000 27.45411 ? 322 HOH B O   1 
HETATM 3628 O O   . HOH H 3 .   ? -30.03391 -23.08840 0.82437   1.000 30.33327 ? 323 HOH B O   1 
HETATM 3629 O O   . HOH H 3 .   ? -24.76472 -27.70397 -7.87721  1.000 26.92209 ? 324 HOH B O   1 
HETATM 3630 O O   . HOH H 3 .   ? -33.86508 -6.19224  -22.50935 1.000 21.31014 ? 325 HOH B O   1 
HETATM 3631 O O   . HOH H 3 .   ? -23.75499 -8.49377  -11.78146 1.000 20.99639 ? 326 HOH B O   1 
HETATM 3632 O O   . HOH H 3 .   ? -22.93497 -16.88795 -0.28054  1.000 25.51955 ? 327 HOH B O   1 
HETATM 3633 O O   . HOH H 3 .   ? -27.07583 -25.64874 -17.09915 1.000 19.67424 ? 328 HOH B O   1 
HETATM 3634 O O   . HOH H 3 .   ? -40.03548 -30.26531 -30.15049 1.000 16.73608 ? 329 HOH B O   1 
HETATM 3635 O O   . HOH H 3 .   ? -27.14106 -14.62909 -6.26648  1.000 18.19359 ? 330 HOH B O   1 
HETATM 3636 O O   . HOH H 3 .   ? -16.54337 -18.41206 -3.42709  1.000 27.12565 ? 331 HOH B O   1 
HETATM 3637 O O   . HOH H 3 .   ? -42.20379 -9.79958  -22.24932 1.000 21.09727 ? 332 HOH B O   1 
HETATM 3638 O O   . HOH H 3 .   ? -38.78201 -23.46204 -28.73246 1.000 14.27910 ? 333 HOH B O   1 
HETATM 3639 O O   . HOH H 3 .   ? -24.72988 -21.19052 -8.53277  1.000 14.66848 ? 334 HOH B O   1 
HETATM 3640 O O   . HOH H 3 .   ? -43.44725 -20.74414 -6.48431  1.000 31.07105 ? 335 HOH B O   1 
HETATM 3641 O O   . HOH H 3 .   ? -37.13447 -6.70097  -24.85076 1.000 25.89360 ? 336 HOH B O   1 
HETATM 3642 O O   . HOH H 3 .   ? -48.26449 -16.22764 -26.12936 1.000 38.75878 ? 337 HOH B O   1 
HETATM 3643 O O   . HOH H 3 .   ? -39.01389 -40.35658 -28.11491 1.000 22.15395 ? 338 HOH B O   1 
HETATM 3644 O O   . HOH H 3 .   ? -14.96043 -13.84939 -16.20263 1.000 14.14914 ? 339 HOH B O   1 
HETATM 3645 O O   . HOH H 3 .   ? -35.06253 -36.67394 -30.86709 1.000 16.39745 ? 340 HOH B O   1 
HETATM 3646 O O   . HOH H 3 .   ? -38.30333 -30.91599 -32.72895 1.000 28.95451 ? 341 HOH B O   1 
HETATM 3647 O O   . HOH H 3 .   ? -18.21720 -16.61788 0.06522   1.000 31.80637 ? 342 HOH B O   1 
HETATM 3648 O O   . HOH H 3 .   ? -35.66808 -15.29558 -29.47401 1.000 13.35231 ? 343 HOH B O   1 
HETATM 3649 O O   . HOH H 3 .   ? -22.00117 -17.37191 -6.36490  1.000 21.73655 ? 344 HOH B O   1 
HETATM 3650 O O   . HOH H 3 .   ? -46.52283 -20.48697 -10.42144 1.000 27.03426 ? 345 HOH B O   1 
HETATM 3651 O O   . HOH H 3 .   ? -55.37456 -38.05112 -25.67971 1.000 38.92832 ? 346 HOH B O   1 
HETATM 3652 O O   . HOH H 3 .   ? -11.75308 -9.93552  -8.70337  1.000 23.44629 ? 347 HOH B O   1 
HETATM 3653 O O   . HOH H 3 .   ? -43.60267 -14.11188 -7.49656  1.000 24.79656 ? 348 HOH B O   1 
HETATM 3654 O O   . HOH H 3 .   ? -40.52281 -11.27823 -3.43237  1.000 32.19684 ? 349 HOH B O   1 
HETATM 3655 O O   . HOH H 3 .   ? -24.51139 -8.94857  -14.59186 1.000 17.22371 ? 350 HOH B O   1 
HETATM 3656 O O   . HOH H 3 .   ? -39.70797 -10.70167 -28.97984 1.000 29.54699 ? 351 HOH B O   1 
HETATM 3657 O O   . HOH H 3 .   ? -32.62381 -6.92306  -2.48231  1.000 31.93753 ? 352 HOH B O   1 
HETATM 3658 O O   . HOH H 3 .   ? -20.34873 -14.94213 -6.79829  1.000 19.19196 ? 353 HOH B O   1 
HETATM 3659 O O   . HOH H 3 .   ? -37.02644 -10.89204 -2.54819  1.000 23.48450 ? 354 HOH B O   1 
HETATM 3660 O O   . HOH H 3 .   ? -30.00313 -18.19912 -2.57343  1.000 18.63159 ? 355 HOH B O   1 
HETATM 3661 O O   . HOH H 3 .   ? -22.89417 -9.16907  -6.36347  1.000 30.57679 ? 356 HOH B O   1 
HETATM 3662 O O   . HOH H 3 .   ? -28.39058 -24.23394 -23.93888 1.000 17.74565 ? 357 HOH B O   1 
HETATM 3663 O O   . HOH H 3 .   ? -42.48765 -10.92485 -10.12596 1.000 24.12633 ? 358 HOH B O   1 
HETATM 3664 O O   . HOH H 3 .   ? -36.00920 -19.74699 -33.42909 1.000 24.98546 ? 359 HOH B O   1 
HETATM 3665 O O   . HOH H 3 .   ? -47.04525 -34.14285 -29.67686 1.000 28.17563 ? 360 HOH B O   1 
HETATM 3666 O O   . HOH H 3 .   ? -49.97262 -44.90656 -13.32583 1.000 26.94259 ? 361 HOH B O   1 
HETATM 3667 O O   . HOH H 3 .   ? -20.16772 -7.82756  -7.14686  1.000 31.50316 ? 362 HOH B O   1 
HETATM 3668 O O   . HOH H 3 .   ? -32.31707 -26.83253 -31.12143 1.000 31.83520 ? 363 HOH B O   1 
HETATM 3669 O O   . HOH H 3 .   ? -44.67935 -41.97549 -15.39278 1.000 29.47841 ? 364 HOH B O   1 
HETATM 3670 O O   . HOH H 3 .   ? -46.52593 -44.57340 -18.82185 1.000 40.32138 ? 365 HOH B O   1 
HETATM 3671 O O   . HOH H 3 .   ? -44.47962 -13.88825 -33.96823 1.000 36.29613 ? 366 HOH B O   1 
HETATM 3672 O O   . HOH H 3 .   ? -46.00790 -31.74108 -4.37831  1.000 29.69559 ? 367 HOH B O   1 
HETATM 3673 O O   . HOH H 3 .   ? -31.70641 -19.55685 1.81476   1.000 32.42647 ? 368 HOH B O   1 
HETATM 3674 O O   . HOH H 3 .   ? -37.43957 -23.96441 -32.20902 1.000 26.53796 ? 369 HOH B O   1 
HETATM 3675 O O   . HOH H 3 .   ? -49.56569 -38.98049 -23.04369 1.000 25.51052 ? 370 HOH B O   1 
HETATM 3676 O O   . HOH H 3 .   ? -51.71830 -46.57858 -12.23614 1.000 37.98460 ? 371 HOH B O   1 
HETATM 3677 O O   . HOH H 3 .   ? -29.61963 -5.24315  -7.28203  1.000 23.86527 ? 372 HOH B O   1 
HETATM 3678 O O   . HOH H 3 .   ? -45.29125 -24.13585 -32.14453 1.000 16.34759 ? 373 HOH B O   1 
HETATM 3679 O O   . HOH H 3 .   ? -45.229   -17.558   -31.689   1.000 30.20022 ? 374 HOH B O   1 
HETATM 3680 O O   . HOH H 3 .   ? -56.72736 -38.26133 -11.86372 1.000 23.55549 ? 375 HOH B O   1 
HETATM 3681 O O   . HOH H 3 .   ? -43.086   -16.121   -1.245    1.000 30.83322 ? 376 HOH B O   1 
HETATM 3682 O O   . HOH H 3 .   ? -43.70662 -41.63073 -22.48122 1.000 18.36894 ? 377 HOH B O   1 
HETATM 3683 O O   . HOH H 3 .   ? -46.00913 -22.45402 -27.40262 1.000 35.47709 ? 378 HOH B O   1 
HETATM 3684 O O   . HOH H 3 .   ? -16.94020 -12.22565 -3.51993  1.000 29.65402 ? 379 HOH B O   1 
HETATM 3685 O O   . HOH H 3 .   ? -22.57707 -8.43988  -8.90779  1.000 31.61493 ? 380 HOH B O   1 
HETATM 3686 O O   . HOH H 3 .   ? -45.68213 -23.68767 -17.40038 1.000 26.05819 ? 381 HOH B O   1 
HETATM 3687 O O   . HOH H 3 .   ? -25.42630 -14.06165 -14.16637 1.000 19.21837 ? 382 HOH B O   1 
HETATM 3688 O O   . HOH H 3 .   ? -36.30252 -4.90528  -8.29206  1.000 30.82804 ? 383 HOH B O   1 
HETATM 3689 O O   . HOH H 3 .   ? -46.56804 -24.82268 -25.18776 1.000 32.69660 ? 384 HOH B O   1 
HETATM 3690 O O   . HOH H 3 .   ? -54.51884 -29.95589 -18.94894 1.000 35.07751 ? 385 HOH B O   1 
HETATM 3691 O O   . HOH H 3 .   ? -39.31926 -22.09347 -26.27844 1.000 18.52086 ? 386 HOH B O   1 
HETATM 3692 O O   . HOH H 3 .   ? -44.24676 -19.68434 -30.63129 1.000 17.45588 ? 387 HOH B O   1 
HETATM 3693 O O   . HOH H 3 .   ? -47.20596 -38.16858 -12.83547 1.000 26.48085 ? 388 HOH B O   1 
HETATM 3694 O O   . HOH H 3 .   ? -42.98381 -43.62382 -16.40507 1.000 34.32178 ? 389 HOH B O   1 
HETATM 3695 O O   . HOH H 3 .   ? -53.06134 -28.27896 -25.84657 1.000 40.15540 ? 390 HOH B O   1 
HETATM 3696 O O   . HOH H 3 .   ? -38.122   -20.835   -34.408   1.000 28.18193 ? 391 HOH B O   1 
HETATM 3697 O O   . HOH H 3 .   ? -24.61420 -17.30997 -10.07448 1.000 22.95894 ? 392 HOH B O   1 
HETATM 3698 O O   . HOH H 3 .   ? -30.36250 -24.54818 -28.22394 1.000 28.77582 ? 393 HOH B O   1 
HETATM 3699 O O   . HOH H 3 .   ? -51.85424 -24.93899 -15.54751 1.000 40.15825 ? 394 HOH B O   1 
HETATM 3700 O O   . HOH H 3 .   ? -34.55991 -11.27387 -2.17556  1.000 24.25692 ? 395 HOH B O   1 
HETATM 3701 O O   . HOH H 3 .   ? -34.76643 -32.31690 -9.94251  1.000 28.23346 ? 396 HOH B O   1 
HETATM 3702 O O   . HOH H 3 .   ? -33.98622 -13.07827 -0.04329  1.000 22.58849 ? 397 HOH B O   1 
HETATM 3703 O O   . HOH H 3 .   ? -25.22848 -25.45344 -2.11596  1.000 31.78302 ? 398 HOH B O   1 
HETATM 3704 O O   . HOH H 3 .   ? -13.37949 -8.43454  -7.29816  1.000 33.54981 ? 399 HOH B O   1 
HETATM 3705 O O   . HOH H 3 .   ? -54.21422 -28.45876 -10.24258 1.000 35.84484 ? 400 HOH B O   1 
HETATM 3706 O O   . HOH H 3 .   ? -45.07198 -38.06789 -26.17655 1.000 31.38123 ? 401 HOH B O   1 
HETATM 3707 O O   . HOH H 3 .   ? -17.48804 -7.03507  -8.03907  1.000 26.59628 ? 402 HOH B O   1 
HETATM 3708 O O   . HOH H 3 .   ? -36.39549 -12.30250 -30.97628 1.000 31.70233 ? 403 HOH B O   1 
HETATM 3709 O O   . HOH H 3 .   ? -56.02895 -31.43665 -20.42800 1.000 38.59367 ? 404 HOH B O   1 
HETATM 3710 O O   . HOH H 3 .   ? -32.73926 -9.00719  -1.02341  1.000 34.54119 ? 405 HOH B O   1 
HETATM 3711 O O   . HOH H 3 .   ? -35.72706 -35.85014 -33.35278 1.000 35.09315 ? 406 HOH B O   1 
HETATM 3712 O O   . HOH H 3 .   ? -10.45708 -12.41898 -7.20033  1.000 32.90569 ? 407 HOH B O   1 
HETATM 3713 O O   . HOH H 3 .   ? -27.70765 -2.94972  -7.54732  1.000 40.88627 ? 408 HOH B O   1 
HETATM 3714 O O   . HOH H 3 .   ? -50.89024 -37.94994 -6.49838  1.000 32.75022 ? 409 HOH B O   1 
HETATM 3715 O O   . HOH H 3 .   ? -47.88080 -45.52689 -14.91728 1.000 31.92245 ? 410 HOH B O   1 
HETATM 3716 O O   . HOH H 3 .   ? -32.92638 -3.58026  -18.03560 1.000 34.28721 ? 411 HOH B O   1 
HETATM 3717 O O   . HOH H 3 .   ? -23.16264 -18.58880 -8.18944  1.000 23.77336 ? 412 HOH B O   1 
HETATM 3718 O O   . HOH H 3 .   ? -27.35115 -27.02967 -22.55605 1.000 25.26303 ? 413 HOH B O   1 
HETATM 3719 O O   . HOH H 3 .   ? -14.00406 -17.77197 -3.54330  1.000 35.20188 ? 414 HOH B O   1 
HETATM 3720 O O   . HOH H 3 .   ? -47.830   -30.702   -2.681    1.000 35.64474 ? 415 HOH B O   1 
HETATM 3721 O O   . HOH H 3 .   ? -56.42622 -19.54172 -10.27621 1.000 42.89270 ? 416 HOH B O   1 
HETATM 3722 O O   . HOH H 3 .   ? -46.389   -19.134   -0.326    1.000 33.45681 ? 417 HOH B O   1 
HETATM 3723 O O   . HOH H 3 .   ? -45.59376 -36.10120 -29.72861 1.000 33.32684 ? 418 HOH B O   1 
HETATM 3724 O O   . HOH H 3 .   ? -44.13174 -8.72953  -10.88734 1.000 29.35740 ? 419 HOH B O   1 
HETATM 3725 O O   . HOH H 3 .   ? -31.53715 -24.42789 1.87730   1.000 35.76273 ? 420 HOH B O   1 
HETATM 3726 O O   . HOH H 3 .   ? -38.70285 -12.76046 3.80991   1.000 41.72137 ? 421 HOH B O   1 
HETATM 3727 O O   . HOH H 3 .   ? -43.06299 -11.33909 -7.29659  1.000 35.55950 ? 422 HOH B O   1 
HETATM 3728 O O   . HOH H 3 .   ? -22.17887 -5.90979  -8.63236  1.000 37.22027 ? 423 HOH B O   1 
HETATM 3729 O O   . HOH H 3 .   ? -34.26207 -18.33790 -33.99971 1.000 32.19853 ? 424 HOH B O   1 
HETATM 3730 O O   . HOH H 3 .   ? -35.50877 -25.49629 -33.93446 1.000 37.54863 ? 425 HOH B O   1 
HETATM 3731 O O   . HOH H 3 .   ? -32.45779 -22.30095 3.47399   1.000 35.18195 ? 426 HOH B O   1 
HETATM 3732 O O   . HOH H 3 .   ? -44.07624 -40.60809 -26.68680 1.000 34.69349 ? 427 HOH B O   1 
HETATM 3733 O O   . HOH H 3 .   ? -44.82780 -14.00878 -4.97572  1.000 33.29911 ? 428 HOH B O   1 
HETATM 3734 O O   . HOH H 3 .   ? -56.46815 -18.99556 -13.58305 1.000 44.13720 ? 429 HOH B O   1 
HETATM 3735 O O   . HOH H 3 .   ? -54.84323 -16.47335 -11.90920 1.000 40.67366 ? 430 HOH B O   1 
HETATM 3736 O O   . HOH H 3 .   ? -55.23148 -17.37950 -14.46731 1.000 44.82224 ? 431 HOH B O   1 
HETATM 3737 O O   . HOH H 3 .   ? -43.61623 -11.82761 -3.31328  1.000 42.98447 ? 432 HOH B O   1 
HETATM 3738 O O   . HOH H 3 .   ? -59.00290 -18.46734 -10.76960 1.000 38.34760 ? 433 HOH B O   1 
HETATM 3739 O O   . HOH H 3 .   ? -57.60045 -15.95791 -12.88552 1.000 40.44489 ? 434 HOH B O   1 
HETATM 3740 O O   . HOH I 3 .   ? -25.28342 -27.96307 -34.31398 1.000 35.36753 ? 301 HOH C O   1 
HETATM 3741 O O   . HOH I 3 .   ? -39.57268 -49.47625 -20.07755 1.000 35.58296 ? 302 HOH C O   1 
HETATM 3742 O O   . HOH I 3 .   ? -22.86208 -31.94230 -1.57229  1.000 33.53690 ? 303 HOH C O   1 
HETATM 3743 O O   . HOH I 3 .   ? -33.22599 -51.64187 -18.57856 1.000 37.78398 ? 304 HOH C O   1 
HETATM 3744 O O   . HOH I 3 .   ? -28.22018 -49.79720 -17.33496 1.000 24.43034 ? 305 HOH C O   1 
HETATM 3745 O O   . HOH I 3 .   ? -21.07361 -43.99038 -30.58275 1.000 32.47918 ? 306 HOH C O   1 
HETATM 3746 O O   . HOH I 3 .   ? 0.59720   -38.98001 -24.28921 1.000 35.65481 ? 307 HOH C O   1 
HETATM 3747 O O   . HOH I 3 .   ? -19.63824 -33.46797 -9.44942  1.000 22.91775 ? 308 HOH C O   1 
HETATM 3748 O O   . HOH I 3 .   ? -1.14100  -43.18967 -18.86820 1.000 28.02156 ? 309 HOH C O   1 
HETATM 3749 O O   . HOH I 3 .   ? -43.54700 -34.30515 -6.88866  1.000 31.00874 ? 310 HOH C O   1 
HETATM 3750 O O   . HOH I 3 .   ? -33.73620 -50.57794 -26.55606 1.000 35.28570 ? 311 HOH C O   1 
HETATM 3751 O O   . HOH I 3 .   ? -41.93019 -46.30799 -11.08843 1.000 27.54429 ? 312 HOH C O   1 
HETATM 3752 O O   . HOH I 3 .   ? -36.68375 -23.36395 -0.65257  1.000 29.69006 ? 313 HOH C O   1 
HETATM 3753 O O   . HOH I 3 .   ? -31.01335 -33.30954 -32.87033 1.000 32.77822 ? 314 HOH C O   1 
HETATM 3754 O O   . HOH I 3 .   ? -22.36080 -35.68062 -0.86475  1.000 30.84246 ? 315 HOH C O   1 
HETATM 3755 O O   . HOH I 3 .   ? -9.85928  -49.97471 -30.23057 1.000 45.84140 ? 316 HOH C O   1 
HETATM 3756 O O   . HOH I 3 .   ? -18.08836 -27.45457 -34.32776 1.000 13.78067 ? 317 HOH C O   1 
HETATM 3757 O O   . HOH I 3 .   ? -26.94456 -37.60681 -31.08743 1.000 14.77217 ? 318 HOH C O   1 
HETATM 3758 O O   . HOH I 3 .   ? -38.47025 -49.02359 -10.86764 1.000 36.15603 ? 319 HOH C O   1 
HETATM 3759 O O   . HOH I 3 .   ? -4.98413  -31.17849 -25.18238 1.000 28.08776 ? 320 HOH C O   1 
HETATM 3760 O O   . HOH I 3 .   ? -2.58181  -47.98037 -31.05501 1.000 39.23206 ? 321 HOH C O   1 
HETATM 3761 O O   . HOH I 3 .   ? -25.33680 -27.06127 -13.62551 1.000 13.06818 ? 322 HOH C O   1 
HETATM 3762 O O   . HOH I 3 .   ? -26.80085 -28.64212 -17.19794 1.000 20.14017 ? 323 HOH C O   1 
HETATM 3763 O O   . HOH I 3 .   ? -15.73076 -33.46997 -14.09964 1.000 20.67090 ? 324 HOH C O   1 
HETATM 3764 O O   . HOH I 3 .   ? -29.12491 -30.39773 -7.78005  1.000 15.63432 ? 325 HOH C O   1 
HETATM 3765 O O   . HOH I 3 .   ? -9.58048  -43.72197 -12.07980 1.000 29.78588 ? 326 HOH C O   1 
HETATM 3766 O O   . HOH I 3 .   ? -40.73185 -45.40561 -24.14037 1.000 33.60271 ? 327 HOH C O   1 
HETATM 3767 O O   . HOH I 3 .   ? -13.93196 -33.90264 -34.09382 1.000 33.56541 ? 328 HOH C O   1 
HETATM 3768 O O   . HOH I 3 .   ? -32.87673 -30.28347 -4.04458  1.000 26.05831 ? 329 HOH C O   1 
HETATM 3769 O O   . HOH I 3 .   ? -24.44468 -28.09928 -2.84072  1.000 33.41664 ? 330 HOH C O   1 
HETATM 3770 O O   . HOH I 3 .   ? -42.02443 -43.22058 -20.61709 1.000 25.75357 ? 331 HOH C O   1 
HETATM 3771 O O   . HOH I 3 .   ? -19.54497 -43.05357 -15.30874 1.000 16.37581 ? 332 HOH C O   1 
HETATM 3772 O O   . HOH I 3 .   ? -27.84121 -37.31956 -3.07638  1.000 23.69867 ? 333 HOH C O   1 
HETATM 3773 O O   . HOH I 3 .   ? -32.81865 -36.07630 -5.22020  1.000 17.52241 ? 334 HOH C O   1 
HETATM 3774 O O   . HOH I 3 .   ? -24.79739 -42.24801 -36.34227 1.000 14.67530 ? 335 HOH C O   1 
HETATM 3775 O O   . HOH I 3 .   ? -29.06368 -49.46510 -5.54863  1.000 37.30984 ? 336 HOH C O   1 
HETATM 3776 O O   . HOH I 3 .   ? -35.14759 -48.51067 -23.83147 1.000 23.84587 ? 337 HOH C O   1 
HETATM 3777 O O   . HOH I 3 .   ? -33.58171 -25.42797 0.11783   1.000 23.83204 ? 338 HOH C O   1 
HETATM 3778 O O   . HOH I 3 .   ? -23.20817 -49.42485 -5.63925  1.000 27.52279 ? 339 HOH C O   1 
HETATM 3779 O O   . HOH I 3 .   ? -7.35952  -40.04029 -32.04776 1.000 36.28181 ? 340 HOH C O   1 
HETATM 3780 O O   . HOH I 3 .   ? -32.64878 -36.61604 -34.08367 1.000 20.92897 ? 341 HOH C O   1 
HETATM 3781 O O   . HOH I 3 .   ? -3.83632  -49.86114 -23.71144 1.000 38.71485 ? 342 HOH C O   1 
HETATM 3782 O O   . HOH I 3 .   ? -35.87902 -30.01054 -3.62452  1.000 19.30782 ? 343 HOH C O   1 
HETATM 3783 O O   . HOH I 3 .   ? -26.94972 -28.37931 -27.54848 1.000 33.83705 ? 344 HOH C O   1 
HETATM 3784 O O   . HOH I 3 .   ? -28.00802 -35.26622 -34.02867 1.000 21.74376 ? 345 HOH C O   1 
HETATM 3785 O O   . HOH I 3 .   ? -39.51022 -34.96237 -3.16455  1.000 34.26652 ? 346 HOH C O   1 
HETATM 3786 O O   . HOH I 3 .   ? -35.49292 -38.99888 -29.37025 1.000 16.26849 ? 347 HOH C O   1 
HETATM 3787 O O   . HOH I 3 .   ? -42.16830 -32.97754 -2.81172  1.000 36.25422 ? 348 HOH C O   1 
HETATM 3788 O O   . HOH I 3 .   ? -21.11849 -34.97945 -34.03442 1.000 16.08946 ? 349 HOH C O   1 
HETATM 3789 O O   . HOH I 3 .   ? -41.39495 -35.22092 -10.98716 1.000 18.78416 ? 350 HOH C O   1 
HETATM 3790 O O   . HOH I 3 .   ? -41.36395 -35.18563 -8.25542  1.000 26.21067 ? 351 HOH C O   1 
HETATM 3791 O O   . HOH I 3 .   ? -32.80103 -32.14854 -8.41713  1.000 19.99207 ? 352 HOH C O   1 
HETATM 3792 O O   . HOH I 3 .   ? -14.69996 -39.40751 -36.54953 1.000 33.64543 ? 353 HOH C O   1 
HETATM 3793 O O   . HOH I 3 .   ? -37.43510 -44.80069 -29.44128 1.000 25.29119 ? 354 HOH C O   1 
HETATM 3794 O O   . HOH I 3 .   ? -34.73395 -51.76691 -15.35741 1.000 31.82112 ? 355 HOH C O   1 
HETATM 3795 O O   . HOH I 3 .   ? -1.68780  -48.26284 -23.56235 1.000 22.11932 ? 356 HOH C O   1 
HETATM 3796 O O   . HOH I 3 .   ? -34.72028 -33.20361 -5.83310  1.000 31.08791 ? 357 HOH C O   1 
HETATM 3797 O O   . HOH I 3 .   ? -19.20909 -29.82809 -9.69980  1.000 13.54153 ? 358 HOH C O   1 
HETATM 3798 O O   . HOH I 3 .   ? -26.27296 -50.16219 -10.93411 1.000 27.16516 ? 359 HOH C O   1 
HETATM 3799 O O   . HOH I 3 .   ? -29.41954 -29.26385 -23.74854 1.000 21.04825 ? 360 HOH C O   1 
HETATM 3800 O O   . HOH I 3 .   ? -44.47004 -27.64001 -1.00910  1.000 26.99904 ? 361 HOH C O   1 
HETATM 3801 O O   . HOH I 3 .   ? -27.21339 -39.09793 -28.71462 1.000 20.49836 ? 362 HOH C O   1 
HETATM 3802 O O   . HOH I 3 .   ? -4.43947  -48.78284 -17.79588 1.000 24.25365 ? 363 HOH C O   1 
HETATM 3803 O O   . HOH I 3 .   ? -7.58547  -33.69862 -29.92801 1.000 21.25894 ? 364 HOH C O   1 
HETATM 3804 O O   . HOH I 3 .   ? -37.877   -35.219   1.246     1.000 35.00993 ? 365 HOH C O   1 
HETATM 3805 O O   . HOH I 3 .   ? -43.97172 -31.22218 -2.69124  1.000 30.65722 ? 366 HOH C O   1 
HETATM 3806 O O   . HOH I 3 .   ? -23.39008 -39.33307 -0.74711  1.000 37.93871 ? 367 HOH C O   1 
HETATM 3807 O O   . HOH I 3 .   ? -24.79745 -27.10127 -11.07229 1.000 14.99275 ? 368 HOH C O   1 
HETATM 3808 O O   . HOH I 3 .   ? -4.66423  -35.20108 -23.51350 1.000 31.80573 ? 369 HOH C O   1 
HETATM 3809 O O   . HOH I 3 .   ? -28.48419 -43.75633 -33.85754 1.000 15.73355 ? 370 HOH C O   1 
HETATM 3810 O O   . HOH I 3 .   ? -24.127   -44.329   -32.114   1.000 34.52875 ? 371 HOH C O   1 
HETATM 3811 O O   . HOH I 3 .   ? 2.02214   -44.55613 -18.37390 1.000 23.52393 ? 372 HOH C O   1 
HETATM 3812 O O   . HOH I 3 .   ? -12.37492 -29.63480 -33.87159 1.000 21.76456 ? 373 HOH C O   1 
HETATM 3813 O O   . HOH I 3 .   ? -29.93541 -31.18392 -28.86198 1.000 28.04566 ? 374 HOH C O   1 
HETATM 3814 O O   . HOH I 3 .   ? -20.97370 -51.67539 -26.14335 1.000 35.84486 ? 375 HOH C O   1 
HETATM 3815 O O   . HOH I 3 .   ? -28.39314 -49.98517 -30.16232 1.000 31.23953 ? 376 HOH C O   1 
HETATM 3816 O O   . HOH I 3 .   ? -30.54533 -47.12219 -3.85662  1.000 27.62417 ? 377 HOH C O   1 
HETATM 3817 O O   . HOH I 3 .   ? -8.89398  -35.96240 -31.84339 1.000 34.27085 ? 378 HOH C O   1 
HETATM 3818 O O   . HOH I 3 .   ? -40.13795 -42.75140 -5.01792  1.000 26.07521 ? 379 HOH C O   1 
HETATM 3819 O O   . HOH I 3 .   ? -20.29070 -45.00018 -22.81947 1.000 26.62517 ? 380 HOH C O   1 
HETATM 3820 O O   . HOH I 3 .   ? -30.97450 -32.10584 1.49119   1.000 32.61842 ? 381 HOH C O   1 
HETATM 3821 O O   . HOH I 3 .   ? -37.68315 -48.55312 -7.67519  1.000 34.20302 ? 382 HOH C O   1 
HETATM 3822 O O   . HOH I 3 .   ? -25.56685 -29.41363 -0.75337  1.000 33.56941 ? 383 HOH C O   1 
HETATM 3823 O O   . HOH I 3 .   ? -22.05574 -32.90696 -36.26278 1.000 31.35098 ? 384 HOH C O   1 
HETATM 3824 O O   . HOH I 3 .   ? -29.52106 -43.81151 -1.20831  1.000 20.29890 ? 385 HOH C O   1 
HETATM 3825 O O   . HOH I 3 .   ? -9.89877  -49.46041 -12.17750 1.000 43.00518 ? 386 HOH C O   1 
HETATM 3826 O O   . HOH I 3 .   ? -25.64437 -47.37783 -31.74137 1.000 35.09195 ? 387 HOH C O   1 
HETATM 3827 O O   . HOH I 3 .   ? -40.82525 -34.76473 -4.92247  1.000 35.99401 ? 388 HOH C O   1 
HETATM 3828 O O   . HOH I 3 .   ? -31.05432 -44.81885 -3.09765  1.000 27.13158 ? 389 HOH C O   1 
HETATM 3829 O O   . HOH I 3 .   ? -11.91219 -49.42767 -26.60439 1.000 39.66278 ? 390 HOH C O   1 
HETATM 3830 O O   . HOH I 3 .   ? -31.88726 -37.65057 2.06380   1.000 38.54014 ? 391 HOH C O   1 
HETATM 3831 O O   . HOH I 3 .   ? -20.30286 -48.64557 -15.66674 1.000 29.70582 ? 392 HOH C O   1 
HETATM 3832 O O   . HOH I 3 .   ? -42.31738 -50.89612 -13.85794 1.000 42.62405 ? 393 HOH C O   1 
HETATM 3833 O O   . HOH I 3 .   ? -30.14210 -50.56327 -12.78823 1.000 34.13019 ? 394 HOH C O   1 
HETATM 3834 O O   . HOH I 3 .   ? -30.02809 -46.01177 -34.62298 1.000 28.31308 ? 395 HOH C O   1 
HETATM 3835 O O   . HOH I 3 .   ? -39.61090 -47.76529 -8.47072  1.000 38.36871 ? 396 HOH C O   1 
HETATM 3836 O O   . HOH I 3 .   ? -27.04842 -51.70584 -15.39736 1.000 34.78349 ? 397 HOH C O   1 
HETATM 3837 O O   . HOH I 3 .   ? -39.55039 -46.65697 -4.26566  1.000 44.30601 ? 398 HOH C O   1 
HETATM 3838 O O   . HOH I 3 .   ? -6.95792  -34.01888 -32.20628 1.000 42.76043 ? 399 HOH C O   1 
HETATM 3839 O O   . HOH I 3 .   ? -35.44665 -23.77080 1.24832   1.000 27.69541 ? 400 HOH C O   1 
HETATM 3840 O O   . HOH I 3 .   ? -43.54907 -31.10346 -0.28673  1.000 34.18612 ? 401 HOH C O   1 
HETATM 3841 O O   . HOH I 3 .   ? -31.72463 -30.31553 -6.66336  1.000 20.31508 ? 402 HOH C O   1 
HETATM 3842 O O   . HOH I 3 .   ? -2.45423  -43.92559 -16.40604 1.000 33.66997 ? 403 HOH C O   1 
HETATM 3843 O O   . HOH I 3 .   ? -26.57642 -29.03699 -25.48906 1.000 29.89978 ? 404 HOH C O   1 
HETATM 3844 O O   . HOH I 3 .   ? -29.63687 -46.31994 0.31386   1.000 37.89650 ? 405 HOH C O   1 
HETATM 3845 O O   . HOH I 3 .   ? -28.97553 -50.88335 -10.09924 1.000 37.75728 ? 406 HOH C O   1 
HETATM 3846 O O   . HOH I 3 .   ? -13.02703 -38.04326 -36.47946 1.000 31.54516 ? 407 HOH C O   1 
HETATM 3847 O O   . HOH I 3 .   ? -30.35900 -32.32897 4.99378   1.000 49.35388 ? 408 HOH C O   1 
HETATM 3848 O O   . HOH I 3 .   ? -29.46791 -33.26615 7.35049   1.000 41.55074 ? 409 HOH C O   1 
HETATM 3849 O O   . HOH I 3 .   ? -39.50673 -43.24120 -26.99956 1.000 36.52714 ? 410 HOH C O   1 
HETATM 3850 O O   . HOH I 3 .   ? -25.706   -44.066   -34.357   1.000 28.03295 ? 411 HOH C O   1 
HETATM 3851 O O   . HOH I 3 .   ? -43.65543 -35.81075 -4.18948  1.000 41.52633 ? 412 HOH C O   1 
HETATM 3852 O O   . HOH I 3 .   ? -11.94402 -32.17032 -34.31156 1.000 31.60140 ? 413 HOH C O   1 
HETATM 3853 O O   . HOH I 3 .   ? -25.20962 -51.28329 -8.80192  1.000 39.99988 ? 414 HOH C O   1 
HETATM 3854 O O   . HOH I 3 .   ? -28.39103 -33.34407 -35.55155 1.000 37.00606 ? 415 HOH C O   1 
HETATM 3855 O O   . HOH I 3 .   ? -39.77667 -46.56275 -1.29103  1.000 44.19684 ? 416 HOH C O   1 
# 
