data_9NG5
# 
_entry.id   9NG5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NG5         pdb_00009ng5 10.2210/pdb9ng5/pdb 
WWPDB D_1000293329 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NG5 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 geiger@chemistry.msu.edu James Geiger H 'principal investigator/group leader' 0000-0002-9443-4488 
3 draths@chemistry.msu.edu Karen Draths ? 'principal investigator/group leader' 0000-0001-7852-1090 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Silva, K.'    1 ? 
'Geiger, J.H.' 2 ? 
'Draths, K.'   3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'cis-CaaD Y103F mutant soaked with acetylencarboxylic acid' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Silva, K.'    1 ? 
primary 'Geiger, J.H.' 2 ? 
primary 'Draths, K.'   3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cis-3-chloroacrylic acid dehalogenase' 18551.582 3  ? ? ? ? 
2 non-polymer syn 'SULFATE ION'                           96.063    3  ? ? ? ? 
3 water       nat water                                   18.015    81 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVFFGEMPAQQMVEYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVFFGEMPAQQMVEYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   VAL n 
1 3   TYR n 
1 4   MET n 
1 5   VAL n 
1 6   TYR n 
1 7   VAL n 
1 8   SER n 
1 9   GLN n 
1 10  ASP n 
1 11  ARG n 
1 12  LEU n 
1 13  THR n 
1 14  PRO n 
1 15  SER n 
1 16  ALA n 
1 17  LYS n 
1 18  HIS n 
1 19  ALA n 
1 20  VAL n 
1 21  ALA n 
1 22  LYS n 
1 23  ALA n 
1 24  ILE n 
1 25  THR n 
1 26  ASP n 
1 27  ALA n 
1 28  HIS n 
1 29  ARG n 
1 30  GLY n 
1 31  LEU n 
1 32  THR n 
1 33  GLY n 
1 34  THR n 
1 35  GLN n 
1 36  HIS n 
1 37  PHE n 
1 38  LEU n 
1 39  ALA n 
1 40  GLN n 
1 41  VAL n 
1 42  ASN n 
1 43  PHE n 
1 44  GLN n 
1 45  GLU n 
1 46  GLN n 
1 47  PRO n 
1 48  ALA n 
1 49  GLY n 
1 50  ASN n 
1 51  VAL n 
1 52  PHE n 
1 53  LEU n 
1 54  GLY n 
1 55  GLY n 
1 56  VAL n 
1 57  GLN n 
1 58  GLN n 
1 59  GLY n 
1 60  GLY n 
1 61  ASP n 
1 62  THR n 
1 63  ILE n 
1 64  PHE n 
1 65  VAL n 
1 66  HIS n 
1 67  GLY n 
1 68  LEU n 
1 69  HIS n 
1 70  ARG n 
1 71  GLU n 
1 72  GLY n 
1 73  ARG n 
1 74  SER n 
1 75  ALA n 
1 76  ASP n 
1 77  LEU n 
1 78  LYS n 
1 79  GLY n 
1 80  GLN n 
1 81  LEU n 
1 82  ALA n 
1 83  GLN n 
1 84  ARG n 
1 85  ILE n 
1 86  VAL n 
1 87  ASP n 
1 88  ASP n 
1 89  VAL n 
1 90  SER n 
1 91  VAL n 
1 92  ALA n 
1 93  ALA n 
1 94  GLU n 
1 95  ILE n 
1 96  ASP n 
1 97  ARG n 
1 98  LYS n 
1 99  HIS n 
1 100 ILE n 
1 101 TRP n 
1 102 VAL n 
1 103 PHE n 
1 104 PHE n 
1 105 GLY n 
1 106 GLU n 
1 107 MET n 
1 108 PRO n 
1 109 ALA n 
1 110 GLN n 
1 111 GLN n 
1 112 MET n 
1 113 VAL n 
1 114 GLU n 
1 115 TYR n 
1 116 GLY n 
1 117 ARG n 
1 118 PHE n 
1 119 LEU n 
1 120 PRO n 
1 121 GLN n 
1 122 PRO n 
1 123 GLY n 
1 124 HIS n 
1 125 GLU n 
1 126 GLY n 
1 127 GLU n 
1 128 TRP n 
1 129 PHE n 
1 130 ASP n 
1 131 ASN n 
1 132 LEU n 
1 133 SER n 
1 134 SER n 
1 135 ASP n 
1 136 GLU n 
1 137 ARG n 
1 138 ALA n 
1 139 PHE n 
1 140 MET n 
1 141 GLU n 
1 142 THR n 
1 143 ASN n 
1 144 VAL n 
1 145 ASP n 
1 146 VAL n 
1 147 SER n 
1 148 ARG n 
1 149 THR n 
1 150 GLU n 
1 151 ASN n 
1 152 LEU n 
1 153 TYR n 
1 154 PHE n 
1 155 GLN n 
1 156 GLY n 
1 157 LEU n 
1 158 GLU n 
1 159 HIS n 
1 160 HIS n 
1 161 HIS n 
1 162 HIS n 
1 163 HIS n 
1 164 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   164 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 cis-caaD 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'coryneform bacterium' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1728 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   1   1   PRO PRO A . n 
A 1 2   VAL 2   2   2   VAL VAL A . n 
A 1 3   TYR 3   3   3   TYR TYR A . n 
A 1 4   MET 4   4   4   MET MET A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   SER 8   8   8   SER SER A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  HIS 28  28  28  HIS HIS A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  HIS 36  36  36  HIS HIS A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  GLN 40  40  40  GLN GLN A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  GLN 44  44  44  GLN GLN A . n 
A 1 45  GLU 45  45  45  GLU GLU A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ASN 50  50  50  ASN ASN A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  THR 62  62  62  THR THR A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  PHE 64  64  64  PHE PHE A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  HIS 66  66  66  HIS HIS A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  HIS 69  69  69  HIS HIS A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  GLN 80  80  80  GLN GLN A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  GLU 94  94  94  GLU GLU A . n 
A 1 95  ILE 95  95  95  ILE ILE A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  LYS 98  98  98  LYS LYS A . n 
A 1 99  HIS 99  99  99  HIS HIS A . n 
A 1 100 ILE 100 100 100 ILE ILE A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 PHE 104 104 104 PHE PHE A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLN 111 111 111 GLN GLN A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 PHE 118 118 118 PHE PHE A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PRO 120 120 120 PRO PRO A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 HIS 124 124 124 HIS HIS A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 ARG 137 137 137 ARG ARG A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 MET 140 140 140 MET MET A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 THR 142 142 142 THR THR A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 VAL 146 146 ?   ?   ?   A . n 
A 1 147 SER 147 147 ?   ?   ?   A . n 
A 1 148 ARG 148 148 ?   ?   ?   A . n 
A 1 149 THR 149 149 ?   ?   ?   A . n 
A 1 150 GLU 150 150 ?   ?   ?   A . n 
A 1 151 ASN 151 151 ?   ?   ?   A . n 
A 1 152 LEU 152 152 ?   ?   ?   A . n 
A 1 153 TYR 153 153 ?   ?   ?   A . n 
A 1 154 PHE 154 154 ?   ?   ?   A . n 
A 1 155 GLN 155 155 ?   ?   ?   A . n 
A 1 156 GLY 156 156 ?   ?   ?   A . n 
A 1 157 LEU 157 157 ?   ?   ?   A . n 
A 1 158 GLU 158 158 ?   ?   ?   A . n 
A 1 159 HIS 159 159 ?   ?   ?   A . n 
A 1 160 HIS 160 160 ?   ?   ?   A . n 
A 1 161 HIS 161 161 ?   ?   ?   A . n 
A 1 162 HIS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 HIS 164 164 ?   ?   ?   A . n 
B 1 1   PRO 1   1   1   PRO PRO B . n 
B 1 2   VAL 2   2   2   VAL VAL B . n 
B 1 3   TYR 3   3   3   TYR TYR B . n 
B 1 4   MET 4   4   4   MET MET B . n 
B 1 5   VAL 5   5   5   VAL VAL B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   VAL 7   7   7   VAL VAL B . n 
B 1 8   SER 8   8   8   SER SER B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  ASP 10  10  10  ASP ASP B . n 
B 1 11  ARG 11  11  11  ARG ARG B . n 
B 1 12  LEU 12  12  12  LEU LEU B . n 
B 1 13  THR 13  13  13  THR THR B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  LYS 17  17  17  LYS LYS B . n 
B 1 18  HIS 18  18  18  HIS HIS B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  ASP 26  26  26  ASP ASP B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  HIS 28  28  28  HIS HIS B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  GLY 30  30  30  GLY GLY B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  GLY 33  33  33  GLY GLY B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  HIS 36  36  36  HIS HIS B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  GLN 40  40  40  GLN GLN B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  PHE 43  43  43  PHE PHE B . n 
B 1 44  GLN 44  44  44  GLN GLN B . n 
B 1 45  GLU 45  45  45  GLU GLU B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  ALA 48  48  48  ALA ALA B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  ASN 50  50  50  ASN ASN B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  GLY 54  54  54  GLY GLY B . n 
B 1 55  GLY 55  55  55  GLY GLY B . n 
B 1 56  VAL 56  56  56  VAL VAL B . n 
B 1 57  GLN 57  57  57  GLN GLN B . n 
B 1 58  GLN 58  58  58  GLN GLN B . n 
B 1 59  GLY 59  59  59  GLY GLY B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  THR 62  62  62  THR THR B . n 
B 1 63  ILE 63  63  63  ILE ILE B . n 
B 1 64  PHE 64  64  64  PHE PHE B . n 
B 1 65  VAL 65  65  65  VAL VAL B . n 
B 1 66  HIS 66  66  66  HIS HIS B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  HIS 69  69  69  HIS HIS B . n 
B 1 70  ARG 70  70  70  ARG ARG B . n 
B 1 71  GLU 71  71  71  GLU GLU B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  ALA 75  75  75  ALA ALA B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  LEU 77  77  77  LEU LEU B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  GLN 80  80  80  GLN GLN B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ALA 82  82  82  ALA ALA B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ARG 84  84  84  ARG ARG B . n 
B 1 85  ILE 85  85  85  ILE ILE B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  ALA 93  93  93  ALA ALA B . n 
B 1 94  GLU 94  94  94  GLU GLU B . n 
B 1 95  ILE 95  95  95  ILE ILE B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  ARG 97  97  97  ARG ARG B . n 
B 1 98  LYS 98  98  98  LYS LYS B . n 
B 1 99  HIS 99  99  99  HIS HIS B . n 
B 1 100 ILE 100 100 100 ILE ILE B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 PHE 104 104 104 PHE PHE B . n 
B 1 105 GLY 105 105 105 GLY GLY B . n 
B 1 106 GLU 106 106 106 GLU GLU B . n 
B 1 107 MET 107 107 107 MET MET B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 GLN 111 111 111 GLN GLN B . n 
B 1 112 MET 112 112 112 MET MET B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 GLU 114 114 114 GLU GLU B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 PHE 118 118 118 PHE PHE B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 PRO 120 120 120 PRO PRO B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLY 123 123 123 GLY GLY B . n 
B 1 124 HIS 124 124 124 HIS HIS B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 GLY 126 126 126 GLY GLY B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 PHE 129 129 129 PHE PHE B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 ASN 131 131 131 ASN ASN B . n 
B 1 132 LEU 132 132 132 LEU LEU B . n 
B 1 133 SER 133 133 133 SER SER B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 ARG 137 137 137 ARG ARG B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 MET 140 140 140 MET MET B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 THR 142 142 142 THR THR B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 VAL 144 144 144 VAL VAL B . n 
B 1 145 ASP 145 145 145 ASP ASP B . n 
B 1 146 VAL 146 146 ?   ?   ?   B . n 
B 1 147 SER 147 147 ?   ?   ?   B . n 
B 1 148 ARG 148 148 ?   ?   ?   B . n 
B 1 149 THR 149 149 ?   ?   ?   B . n 
B 1 150 GLU 150 150 ?   ?   ?   B . n 
B 1 151 ASN 151 151 ?   ?   ?   B . n 
B 1 152 LEU 152 152 ?   ?   ?   B . n 
B 1 153 TYR 153 153 ?   ?   ?   B . n 
B 1 154 PHE 154 154 ?   ?   ?   B . n 
B 1 155 GLN 155 155 ?   ?   ?   B . n 
B 1 156 GLY 156 156 ?   ?   ?   B . n 
B 1 157 LEU 157 157 ?   ?   ?   B . n 
B 1 158 GLU 158 158 ?   ?   ?   B . n 
B 1 159 HIS 159 159 ?   ?   ?   B . n 
B 1 160 HIS 160 160 ?   ?   ?   B . n 
B 1 161 HIS 161 161 ?   ?   ?   B . n 
B 1 162 HIS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 HIS 164 164 ?   ?   ?   B . n 
C 1 1   PRO 1   1   1   PRO PRO C . n 
C 1 2   VAL 2   2   2   VAL VAL C . n 
C 1 3   TYR 3   3   3   TYR TYR C . n 
C 1 4   MET 4   4   4   MET MET C . n 
C 1 5   VAL 5   5   5   VAL VAL C . n 
C 1 6   TYR 6   6   6   TYR TYR C . n 
C 1 7   VAL 7   7   7   VAL VAL C . n 
C 1 8   SER 8   8   8   SER SER C . n 
C 1 9   GLN 9   9   9   GLN GLN C . n 
C 1 10  ASP 10  10  10  ASP ASP C . n 
C 1 11  ARG 11  11  11  ARG ARG C . n 
C 1 12  LEU 12  12  12  LEU LEU C . n 
C 1 13  THR 13  13  13  THR THR C . n 
C 1 14  PRO 14  14  14  PRO PRO C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  LYS 17  17  17  LYS LYS C . n 
C 1 18  HIS 18  18  18  HIS HIS C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  VAL 20  20  20  VAL VAL C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  LYS 22  22  22  LYS LYS C . n 
C 1 23  ALA 23  23  23  ALA ALA C . n 
C 1 24  ILE 24  24  24  ILE ILE C . n 
C 1 25  THR 25  25  25  THR THR C . n 
C 1 26  ASP 26  26  26  ASP ASP C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  HIS 28  28  28  HIS HIS C . n 
C 1 29  ARG 29  29  29  ARG ARG C . n 
C 1 30  GLY 30  30  30  GLY GLY C . n 
C 1 31  LEU 31  31  31  LEU LEU C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  GLY 33  33  33  GLY GLY C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  HIS 36  36  36  HIS HIS C . n 
C 1 37  PHE 37  37  37  PHE PHE C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  ALA 39  39  39  ALA ALA C . n 
C 1 40  GLN 40  40  40  GLN GLN C . n 
C 1 41  VAL 41  41  41  VAL VAL C . n 
C 1 42  ASN 42  42  42  ASN ASN C . n 
C 1 43  PHE 43  43  43  PHE PHE C . n 
C 1 44  GLN 44  44  44  GLN GLN C . n 
C 1 45  GLU 45  45  45  GLU GLU C . n 
C 1 46  GLN 46  46  46  GLN GLN C . n 
C 1 47  PRO 47  47  47  PRO PRO C . n 
C 1 48  ALA 48  48  48  ALA ALA C . n 
C 1 49  GLY 49  49  49  GLY GLY C . n 
C 1 50  ASN 50  50  50  ASN ASN C . n 
C 1 51  VAL 51  51  51  VAL VAL C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  LEU 53  53  53  LEU LEU C . n 
C 1 54  GLY 54  54  54  GLY GLY C . n 
C 1 55  GLY 55  55  55  GLY GLY C . n 
C 1 56  VAL 56  56  56  VAL VAL C . n 
C 1 57  GLN 57  57  57  GLN GLN C . n 
C 1 58  GLN 58  58  58  GLN GLN C . n 
C 1 59  GLY 59  59  59  GLY GLY C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  ASP 61  61  61  ASP ASP C . n 
C 1 62  THR 62  62  62  THR THR C . n 
C 1 63  ILE 63  63  63  ILE ILE C . n 
C 1 64  PHE 64  64  64  PHE PHE C . n 
C 1 65  VAL 65  65  65  VAL VAL C . n 
C 1 66  HIS 66  66  66  HIS HIS C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  HIS 69  69  69  HIS HIS C . n 
C 1 70  ARG 70  70  70  ARG ARG C . n 
C 1 71  GLU 71  71  71  GLU GLU C . n 
C 1 72  GLY 72  72  72  GLY GLY C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  SER 74  74  74  SER SER C . n 
C 1 75  ALA 75  75  75  ALA ALA C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  LEU 77  77  77  LEU LEU C . n 
C 1 78  LYS 78  78  78  LYS LYS C . n 
C 1 79  GLY 79  79  79  GLY GLY C . n 
C 1 80  GLN 80  80  80  GLN GLN C . n 
C 1 81  LEU 81  81  81  LEU LEU C . n 
C 1 82  ALA 82  82  82  ALA ALA C . n 
C 1 83  GLN 83  83  83  GLN GLN C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  ILE 85  85  85  ILE ILE C . n 
C 1 86  VAL 86  86  86  VAL VAL C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  ASP 88  88  88  ASP ASP C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  SER 90  90  90  SER SER C . n 
C 1 91  VAL 91  91  91  VAL VAL C . n 
C 1 92  ALA 92  92  92  ALA ALA C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  GLU 94  94  94  GLU GLU C . n 
C 1 95  ILE 95  95  95  ILE ILE C . n 
C 1 96  ASP 96  96  96  ASP ASP C . n 
C 1 97  ARG 97  97  97  ARG ARG C . n 
C 1 98  LYS 98  98  98  LYS LYS C . n 
C 1 99  HIS 99  99  99  HIS HIS C . n 
C 1 100 ILE 100 100 100 ILE ILE C . n 
C 1 101 TRP 101 101 101 TRP TRP C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 PHE 103 103 103 PHE PHE C . n 
C 1 104 PHE 104 104 104 PHE PHE C . n 
C 1 105 GLY 105 105 105 GLY GLY C . n 
C 1 106 GLU 106 106 106 GLU GLU C . n 
C 1 107 MET 107 107 107 MET MET C . n 
C 1 108 PRO 108 108 108 PRO PRO C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 GLN 110 110 110 GLN GLN C . n 
C 1 111 GLN 111 111 111 GLN GLN C . n 
C 1 112 MET 112 112 112 MET MET C . n 
C 1 113 VAL 113 113 113 VAL VAL C . n 
C 1 114 GLU 114 114 114 GLU GLU C . n 
C 1 115 TYR 115 115 115 TYR TYR C . n 
C 1 116 GLY 116 116 116 GLY GLY C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 PHE 118 118 118 PHE PHE C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 PRO 120 120 120 PRO PRO C . n 
C 1 121 GLN 121 121 121 GLN GLN C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLY 123 123 123 GLY GLY C . n 
C 1 124 HIS 124 124 124 HIS HIS C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 GLY 126 126 126 GLY GLY C . n 
C 1 127 GLU 127 127 127 GLU GLU C . n 
C 1 128 TRP 128 128 128 TRP TRP C . n 
C 1 129 PHE 129 129 129 PHE PHE C . n 
C 1 130 ASP 130 130 130 ASP ASP C . n 
C 1 131 ASN 131 131 131 ASN ASN C . n 
C 1 132 LEU 132 132 132 LEU LEU C . n 
C 1 133 SER 133 133 133 SER SER C . n 
C 1 134 SER 134 134 134 SER SER C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 GLU 136 136 136 GLU GLU C . n 
C 1 137 ARG 137 137 137 ARG ARG C . n 
C 1 138 ALA 138 138 138 ALA ALA C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 MET 140 140 140 MET MET C . n 
C 1 141 GLU 141 141 141 GLU GLU C . n 
C 1 142 THR 142 142 142 THR THR C . n 
C 1 143 ASN 143 143 143 ASN ASN C . n 
C 1 144 VAL 144 144 144 VAL VAL C . n 
C 1 145 ASP 145 145 145 ASP ASP C . n 
C 1 146 VAL 146 146 ?   ?   ?   C . n 
C 1 147 SER 147 147 ?   ?   ?   C . n 
C 1 148 ARG 148 148 ?   ?   ?   C . n 
C 1 149 THR 149 149 ?   ?   ?   C . n 
C 1 150 GLU 150 150 ?   ?   ?   C . n 
C 1 151 ASN 151 151 ?   ?   ?   C . n 
C 1 152 LEU 152 152 ?   ?   ?   C . n 
C 1 153 TYR 153 153 ?   ?   ?   C . n 
C 1 154 PHE 154 154 ?   ?   ?   C . n 
C 1 155 GLN 155 155 ?   ?   ?   C . n 
C 1 156 GLY 156 156 ?   ?   ?   C . n 
C 1 157 LEU 157 157 ?   ?   ?   C . n 
C 1 158 GLU 158 158 ?   ?   ?   C . n 
C 1 159 HIS 159 159 ?   ?   ?   C . n 
C 1 160 HIS 160 160 ?   ?   ?   C . n 
C 1 161 HIS 161 161 ?   ?   ?   C . n 
C 1 162 HIS 162 162 ?   ?   ?   C . n 
C 1 163 HIS 163 163 ?   ?   ?   C . n 
C 1 164 HIS 164 164 ?   ?   ?   C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 SO4 1  201 2  SO4 SO4 A . 
E 2 SO4 1  201 1  SO4 SO4 B . 
F 2 SO4 1  201 3  SO4 SO4 C . 
G 3 HOH 1  301 15 HOH HOH A . 
G 3 HOH 2  302 6  HOH HOH A . 
G 3 HOH 3  303 64 HOH HOH A . 
G 3 HOH 4  304 37 HOH HOH A . 
G 3 HOH 5  305 20 HOH HOH A . 
G 3 HOH 6  306 23 HOH HOH A . 
G 3 HOH 7  307 7  HOH HOH A . 
G 3 HOH 8  308 66 HOH HOH A . 
G 3 HOH 9  309 79 HOH HOH A . 
G 3 HOH 10 310 14 HOH HOH A . 
G 3 HOH 11 311 56 HOH HOH A . 
G 3 HOH 12 312 78 HOH HOH A . 
G 3 HOH 13 313 44 HOH HOH A . 
G 3 HOH 14 314 30 HOH HOH A . 
G 3 HOH 15 315 16 HOH HOH A . 
G 3 HOH 16 316 22 HOH HOH A . 
G 3 HOH 17 317 36 HOH HOH A . 
G 3 HOH 18 318 10 HOH HOH A . 
G 3 HOH 19 319 69 HOH HOH A . 
G 3 HOH 20 320 13 HOH HOH A . 
G 3 HOH 21 321 71 HOH HOH A . 
G 3 HOH 22 322 77 HOH HOH A . 
G 3 HOH 23 323 39 HOH HOH A . 
G 3 HOH 24 324 61 HOH HOH A . 
G 3 HOH 25 325 42 HOH HOH A . 
G 3 HOH 26 326 1  HOH HOH A . 
G 3 HOH 27 327 49 HOH HOH A . 
G 3 HOH 28 328 51 HOH HOH A . 
G 3 HOH 29 329 41 HOH HOH A . 
G 3 HOH 30 330 72 HOH HOH A . 
G 3 HOH 31 331 47 HOH HOH A . 
G 3 HOH 32 332 58 HOH HOH A . 
H 3 HOH 1  301 35 HOH HOH B . 
H 3 HOH 2  302 75 HOH HOH B . 
H 3 HOH 3  303 27 HOH HOH B . 
H 3 HOH 4  304 68 HOH HOH B . 
H 3 HOH 5  305 21 HOH HOH B . 
H 3 HOH 6  306 26 HOH HOH B . 
H 3 HOH 7  307 24 HOH HOH B . 
H 3 HOH 8  308 3  HOH HOH B . 
H 3 HOH 9  309 63 HOH HOH B . 
H 3 HOH 10 310 29 HOH HOH B . 
H 3 HOH 11 311 12 HOH HOH B . 
H 3 HOH 12 312 74 HOH HOH B . 
H 3 HOH 13 313 76 HOH HOH B . 
H 3 HOH 14 314 67 HOH HOH B . 
H 3 HOH 15 315 17 HOH HOH B . 
H 3 HOH 16 316 48 HOH HOH B . 
H 3 HOH 17 317 55 HOH HOH B . 
H 3 HOH 18 318 81 HOH HOH B . 
H 3 HOH 19 319 53 HOH HOH B . 
H 3 HOH 20 320 45 HOH HOH B . 
H 3 HOH 21 321 60 HOH HOH B . 
H 3 HOH 22 322 5  HOH HOH B . 
H 3 HOH 23 323 73 HOH HOH B . 
I 3 HOH 1  301 65 HOH HOH C . 
I 3 HOH 2  302 8  HOH HOH C . 
I 3 HOH 3  303 57 HOH HOH C . 
I 3 HOH 4  304 34 HOH HOH C . 
I 3 HOH 5  305 31 HOH HOH C . 
I 3 HOH 6  306 59 HOH HOH C . 
I 3 HOH 7  307 4  HOH HOH C . 
I 3 HOH 8  308 38 HOH HOH C . 
I 3 HOH 9  309 18 HOH HOH C . 
I 3 HOH 10 310 70 HOH HOH C . 
I 3 HOH 11 311 80 HOH HOH C . 
I 3 HOH 12 312 33 HOH HOH C . 
I 3 HOH 13 313 54 HOH HOH C . 
I 3 HOH 14 314 43 HOH HOH C . 
I 3 HOH 15 315 52 HOH HOH C . 
I 3 HOH 16 316 62 HOH HOH C . 
I 3 HOH 17 317 2  HOH HOH C . 
I 3 HOH 18 318 40 HOH HOH C . 
I 3 HOH 19 319 11 HOH HOH C . 
I 3 HOH 20 320 19 HOH HOH C . 
I 3 HOH 21 321 25 HOH HOH C . 
I 3 HOH 22 322 50 HOH HOH C . 
I 3 HOH 23 323 32 HOH HOH C . 
I 3 HOH 24 324 28 HOH HOH C . 
I 3 HOH 25 325 46 HOH HOH C . 
I 3 HOH 26 326 9  HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.21.2_5419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NG5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     60.259 
_cell.length_a_esd                 ? 
_cell.length_b                     101.341 
_cell.length_b_esd                 ? 
_cell.length_c                     137.573 
_cell.length_c_esd                 ? 
_cell.volume                       840118.046 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NG5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NG5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.89 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          34.81 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M magnesium sulfate hep-tahydrate 20% w/v PEG 3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-09-22 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.13 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 23-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.13 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   23-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          29.22 
_reflns.entry_id                                       9NG5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.28 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     17389 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           89.2 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                8.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          7.13 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.071 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.30 
_reflns_shell.d_res_low                                     2.34 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             917 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.301 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               29.48 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NG5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.28 
_refine.ls_d_res_low                             29.43 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     16171 
_refine.ls_number_reflns_R_free                  1605 
_refine.ls_number_reflns_R_work                  14566 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    82.57 
_refine.ls_percent_reflns_R_free                 9.93 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2464 
_refine.ls_R_factor_R_free                       0.3539 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2344 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 37.7687 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.5041 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.28 
_refine_hist.d_res_low                        29.43 
_refine_hist.number_atoms_solvent             81 
_refine_hist.number_atoms_total               3519 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3423 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         15 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0078  ? 3519 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9515  ? 4764 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0516  ? 495  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0088  ? 639  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 20.8870 ? 1260 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.28 2.36  . . 119 1105 68.65 . . . . 0.2939 . . . . . . . . . . . . . . . 0.4340 
'X-RAY DIFFRACTION' 2.36 2.44  . . 142 1315 84.37 . . . . 0.2906 . . . . . . . . . . . . . . . 0.4044 
'X-RAY DIFFRACTION' 2.44 2.54  . . 162 1387 87.81 . . . . 0.2753 . . . . . . . . . . . . . . . 0.4198 
'X-RAY DIFFRACTION' 2.54 2.65  . . 146 1390 87.97 . . . . 0.2785 . . . . . . . . . . . . . . . 0.3928 
'X-RAY DIFFRACTION' 2.65 2.79  . . 162 1430 90.25 . . . . 0.2640 . . . . . . . . . . . . . . . 0.3889 
'X-RAY DIFFRACTION' 2.79 2.97  . . 158 1428 89.81 . . . . 0.2280 . . . . . . . . . . . . . . . 0.4009 
'X-RAY DIFFRACTION' 2.97 3.20  . . 149 1391 87.30 . . . . 0.2323 . . . . . . . . . . . . . . . 0.3297 
'X-RAY DIFFRACTION' 3.20 3.52  . . 138 1321 82.20 . . . . 0.2267 . . . . . . . . . . . . . . . 0.3646 
'X-RAY DIFFRACTION' 3.52 4.02  . . 136 1116 69.94 . . . . 0.2125 . . . . . . . . . . . . . . . 0.3258 
'X-RAY DIFFRACTION' 4.03 5.07  . . 121 1127 68.84 . . . . 0.1903 . . . . . . . . . . . . . . . 0.3091 
'X-RAY DIFFRACTION' 5.07 29.43 . . 172 1556 91.48 . . . . 0.2296 . . . . . . . . . . . . . . . 0.3231 
# 
_struct.entry_id                     9NG5 
_struct.title                        'cis-CaaD Y103F mutant soaked with acetylencarboxylic acid' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NG5 
_struct_keywords.text            'Tautomerase, cis-CaaD, acetylenecaarboxylic acid, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q6VPE5_9CORY 
_struct_ref.pdbx_db_accession          Q6VPE5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVEYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRT
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NG5 A 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
2 1 9NG5 B 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
3 1 9NG5 C 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9NG5 PHE A 103 ? UNP Q6VPE5 TYR 104 'engineered mutation' 103 1  
1 9NG5 GLU A 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 2  
1 9NG5 ASN A 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 3  
1 9NG5 LEU A 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 4  
1 9NG5 TYR A 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 5  
1 9NG5 PHE A 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 6  
1 9NG5 GLN A 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 7  
1 9NG5 GLY A 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 8  
1 9NG5 LEU A 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 9  
1 9NG5 GLU A 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 10 
1 9NG5 HIS A 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 11 
1 9NG5 HIS A 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 12 
1 9NG5 HIS A 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 13 
1 9NG5 HIS A 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 14 
1 9NG5 HIS A 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 15 
1 9NG5 HIS A 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 16 
2 9NG5 PHE B 103 ? UNP Q6VPE5 TYR 104 'engineered mutation' 103 17 
2 9NG5 GLU B 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 18 
2 9NG5 ASN B 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 19 
2 9NG5 LEU B 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 20 
2 9NG5 TYR B 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 21 
2 9NG5 PHE B 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 22 
2 9NG5 GLN B 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 23 
2 9NG5 GLY B 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 24 
2 9NG5 LEU B 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 25 
2 9NG5 GLU B 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 26 
2 9NG5 HIS B 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 27 
2 9NG5 HIS B 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 28 
2 9NG5 HIS B 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 29 
2 9NG5 HIS B 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 30 
2 9NG5 HIS B 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 31 
2 9NG5 HIS B 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 32 
3 9NG5 PHE C 103 ? UNP Q6VPE5 TYR 104 'engineered mutation' 103 33 
3 9NG5 GLU C 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 34 
3 9NG5 ASN C 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 35 
3 9NG5 LEU C 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 36 
3 9NG5 TYR C 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 37 
3 9NG5 PHE C 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 38 
3 9NG5 GLN C 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 39 
3 9NG5 GLY C 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 40 
3 9NG5 LEU C 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 41 
3 9NG5 GLU C 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 42 
3 9NG5 HIS C 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 43 
3 9NG5 HIS C 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 44 
3 9NG5 HIS C 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 45 
3 9NG5 HIS C 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 46 
3 9NG5 HIS C 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 47 
3 9NG5 HIS C 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 48 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 8990  ? 
1 MORE         -115  ? 
1 'SSA (A^2)'  15730 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 13  ? GLY A 33  ? THR A 13  GLY A 33  1 ? 21 
HELX_P HELX_P2  AA2 GLN A 35  ? LEU A 38  ? GLN A 35  LEU A 38  5 ? 4  
HELX_P HELX_P3  AA3 SER A 74  ? GLU A 94  ? SER A 74  GLU A 94  1 ? 21 
HELX_P HELX_P4  AA4 ASP A 96  ? LYS A 98  ? ASP A 96  LYS A 98  5 ? 3  
HELX_P HELX_P5  AA5 PRO A 108 ? GLN A 110 ? PRO A 108 GLN A 110 5 ? 3  
HELX_P HELX_P6  AA6 HIS A 124 ? ASP A 130 ? HIS A 124 ASP A 130 1 ? 7  
HELX_P HELX_P7  AA7 SER A 133 ? THR A 142 ? SER A 133 THR A 142 1 ? 10 
HELX_P HELX_P8  AA8 THR B 13  ? GLY B 33  ? THR B 13  GLY B 33  1 ? 21 
HELX_P HELX_P9  AA9 GLN B 35  ? LEU B 38  ? GLN B 35  LEU B 38  5 ? 4  
HELX_P HELX_P10 AB1 SER B 74  ? GLU B 94  ? SER B 74  GLU B 94  1 ? 21 
HELX_P HELX_P11 AB2 ASP B 96  ? LYS B 98  ? ASP B 96  LYS B 98  5 ? 3  
HELX_P HELX_P12 AB3 PRO B 108 ? GLN B 110 ? PRO B 108 GLN B 110 5 ? 3  
HELX_P HELX_P13 AB4 GLU B 125 ? ASN B 131 ? GLU B 125 ASN B 131 1 ? 7  
HELX_P HELX_P14 AB5 SER B 133 ? ASN B 143 ? SER B 133 ASN B 143 1 ? 11 
HELX_P HELX_P15 AB6 THR C 13  ? GLY C 33  ? THR C 13  GLY C 33  1 ? 21 
HELX_P HELX_P16 AB7 GLN C 35  ? LEU C 38  ? GLN C 35  LEU C 38  5 ? 4  
HELX_P HELX_P17 AB8 SER C 74  ? ALA C 93  ? SER C 74  ALA C 93  1 ? 20 
HELX_P HELX_P18 AB9 ASP C 96  ? LYS C 98  ? ASP C 96  LYS C 98  5 ? 3  
HELX_P HELX_P19 AC1 PRO C 108 ? GLN C 110 ? PRO C 108 GLN C 110 5 ? 3  
HELX_P HELX_P20 AC2 HIS C 124 ? ASN C 131 ? HIS C 124 ASN C 131 1 ? 8  
HELX_P HELX_P21 AC3 SER C 133 ? ASN C 143 ? SER C 133 ASN C 143 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 8 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
AA2 5 6 ? parallel      
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? anti-parallel 
AA3 5 6 ? parallel      
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG B 117 ? PHE B 118 ? ARG B 117 PHE B 118 
AA1 2 MET B 112 ? GLU B 114 ? MET B 112 GLU B 114 
AA1 3 ILE A 100 ? MET A 107 ? ILE A 100 MET A 107 
AA1 4 ILE A 63  ? ARG A 70  ? ILE A 63  ARG A 70  
AA1 5 VAL A 2   ? SER A 8   ? VAL A 2   SER A 8   
AA1 6 GLN A 40  ? GLN A 46  ? GLN A 40  GLN A 46  
AA1 7 VAL C 51  ? LEU C 53  ? VAL C 51  LEU C 53  
AA1 8 VAL C 56  ? GLN C 57  ? VAL C 56  GLN C 57  
AA2 1 VAL A 56  ? GLN A 57  ? VAL A 56  GLN A 57  
AA2 2 VAL A 51  ? LEU A 53  ? VAL A 51  LEU A 53  
AA2 3 GLN B 40  ? GLN B 46  ? GLN B 40  GLN B 46  
AA2 4 VAL B 2   ? SER B 8   ? VAL B 2   SER B 8   
AA2 5 ILE B 63  ? ARG B 70  ? ILE B 63  ARG B 70  
AA2 6 ILE B 100 ? MET B 107 ? ILE B 100 MET B 107 
AA2 7 MET C 112 ? GLU C 114 ? MET C 112 GLU C 114 
AA2 8 ARG C 117 ? PHE C 118 ? ARG C 117 PHE C 118 
AA3 1 ARG A 117 ? PHE A 118 ? ARG A 117 PHE A 118 
AA3 2 MET A 112 ? GLU A 114 ? MET A 112 GLU A 114 
AA3 3 ILE C 100 ? MET C 107 ? ILE C 100 MET C 107 
AA3 4 ILE C 63  ? ARG C 70  ? ILE C 63  ARG C 70  
AA3 5 VAL C 2   ? SER C 8   ? VAL C 2   SER C 8   
AA3 6 GLN C 40  ? GLN C 46  ? GLN C 40  GLN C 46  
AA3 7 VAL B 51  ? LEU B 53  ? VAL B 51  LEU B 53  
AA3 8 VAL B 56  ? GLN B 57  ? VAL B 56  GLN B 57  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ARG B 117 ? O ARG B 117 N GLU B 114 ? N GLU B 114 
AA1 2 3 O VAL B 113 ? O VAL B 113 N VAL A 102 ? N VAL A 102 
AA1 3 4 O TRP A 101 ? O TRP A 101 N VAL A 65  ? N VAL A 65  
AA1 4 5 O PHE A 64  ? O PHE A 64  N TYR A 6   ? N TYR A 6   
AA1 5 6 N TYR A 3   ? N TYR A 3   O ASN A 42  ? O ASN A 42  
AA1 6 7 N VAL A 41  ? N VAL A 41  O PHE C 52  ? O PHE C 52  
AA1 7 8 N LEU C 53  ? N LEU C 53  O VAL C 56  ? O VAL C 56  
AA2 1 2 O VAL A 56  ? O VAL A 56  N LEU A 53  ? N LEU A 53  
AA2 2 3 N PHE A 52  ? N PHE A 52  O VAL B 41  ? O VAL B 41  
AA2 3 4 O GLN B 44  ? O GLN B 44  N VAL B 5   ? N VAL B 5   
AA2 4 5 N MET B 4   ? N MET B 4   O HIS B 66  ? O HIS B 66  
AA2 5 6 N VAL B 65  ? N VAL B 65  O TRP B 101 ? O TRP B 101 
AA2 6 7 N VAL B 102 ? N VAL B 102 O VAL C 113 ? O VAL C 113 
AA2 7 8 N GLU C 114 ? N GLU C 114 O ARG C 117 ? O ARG C 117 
AA3 1 2 O ARG A 117 ? O ARG A 117 N GLU A 114 ? N GLU A 114 
AA3 2 3 N VAL A 113 ? N VAL A 113 O VAL C 102 ? O VAL C 102 
AA3 3 4 O TRP C 101 ? O TRP C 101 N VAL C 65  ? N VAL C 65  
AA3 4 5 O PHE C 64  ? O PHE C 64  N TYR C 6   ? N TYR C 6   
AA3 5 6 N TYR C 3   ? N TYR C 3   O ASN C 42  ? O ASN C 42  
AA3 6 7 O VAL C 41  ? O VAL C 41  N PHE B 52  ? N PHE B 52  
AA3 7 8 N LEU B 53  ? N LEU B 53  O VAL B 56  ? O VAL B 56  
# 
_pdbx_entry_details.entry_id                   9NG5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 10  ? ? 81.50   -11.85  
2  1 PRO A 122 ? ? -58.49  5.89    
3  1 ASN A 143 ? ? -108.34 55.51   
4  1 ASP B 10  ? ? 56.36   17.65   
5  1 ALA B 48  ? ? -49.54  164.90  
6  1 HIS B 124 ? ? -155.91 -110.86 
7  1 GLU B 125 ? ? 78.36   -67.24  
8  1 ASP C 10  ? ? 93.54   2.94    
9  1 LYS C 98  ? ? -66.56  2.05    
10 1 HIS C 124 ? ? -170.38 -17.28  
11 1 ASN C 131 ? ? -103.27 46.34   
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     332 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   G 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A VAL 146 ? A VAL 146 
2  1 Y 1 A SER 147 ? A SER 147 
3  1 Y 1 A ARG 148 ? A ARG 148 
4  1 Y 1 A THR 149 ? A THR 149 
5  1 Y 1 A GLU 150 ? A GLU 150 
6  1 Y 1 A ASN 151 ? A ASN 151 
7  1 Y 1 A LEU 152 ? A LEU 152 
8  1 Y 1 A TYR 153 ? A TYR 153 
9  1 Y 1 A PHE 154 ? A PHE 154 
10 1 Y 1 A GLN 155 ? A GLN 155 
11 1 Y 1 A GLY 156 ? A GLY 156 
12 1 Y 1 A LEU 157 ? A LEU 157 
13 1 Y 1 A GLU 158 ? A GLU 158 
14 1 Y 1 A HIS 159 ? A HIS 159 
15 1 Y 1 A HIS 160 ? A HIS 160 
16 1 Y 1 A HIS 161 ? A HIS 161 
17 1 Y 1 A HIS 162 ? A HIS 162 
18 1 Y 1 A HIS 163 ? A HIS 163 
19 1 Y 1 A HIS 164 ? A HIS 164 
20 1 Y 1 B VAL 146 ? B VAL 146 
21 1 Y 1 B SER 147 ? B SER 147 
22 1 Y 1 B ARG 148 ? B ARG 148 
23 1 Y 1 B THR 149 ? B THR 149 
24 1 Y 1 B GLU 150 ? B GLU 150 
25 1 Y 1 B ASN 151 ? B ASN 151 
26 1 Y 1 B LEU 152 ? B LEU 152 
27 1 Y 1 B TYR 153 ? B TYR 153 
28 1 Y 1 B PHE 154 ? B PHE 154 
29 1 Y 1 B GLN 155 ? B GLN 155 
30 1 Y 1 B GLY 156 ? B GLY 156 
31 1 Y 1 B LEU 157 ? B LEU 157 
32 1 Y 1 B GLU 158 ? B GLU 158 
33 1 Y 1 B HIS 159 ? B HIS 159 
34 1 Y 1 B HIS 160 ? B HIS 160 
35 1 Y 1 B HIS 161 ? B HIS 161 
36 1 Y 1 B HIS 162 ? B HIS 162 
37 1 Y 1 B HIS 163 ? B HIS 163 
38 1 Y 1 B HIS 164 ? B HIS 164 
39 1 Y 1 C VAL 146 ? C VAL 146 
40 1 Y 1 C SER 147 ? C SER 147 
41 1 Y 1 C ARG 148 ? C ARG 148 
42 1 Y 1 C THR 149 ? C THR 149 
43 1 Y 1 C GLU 150 ? C GLU 150 
44 1 Y 1 C ASN 151 ? C ASN 151 
45 1 Y 1 C LEU 152 ? C LEU 152 
46 1 Y 1 C TYR 153 ? C TYR 153 
47 1 Y 1 C PHE 154 ? C PHE 154 
48 1 Y 1 C GLN 155 ? C GLN 155 
49 1 Y 1 C GLY 156 ? C GLY 156 
50 1 Y 1 C LEU 157 ? C LEU 157 
51 1 Y 1 C GLU 158 ? C GLU 158 
52 1 Y 1 C HIS 159 ? C HIS 159 
53 1 Y 1 C HIS 160 ? C HIS 160 
54 1 Y 1 C HIS 161 ? C HIS 161 
55 1 Y 1 C HIS 162 ? C HIS 162 
56 1 Y 1 C HIS 163 ? C HIS 163 
57 1 Y 1 C HIS 164 ? C HIS 164 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
HOH O    O N N 144 
HOH H1   H N N 145 
HOH H2   H N N 146 
ILE N    N N N 147 
ILE CA   C N S 148 
ILE C    C N N 149 
ILE O    O N N 150 
ILE CB   C N S 151 
ILE CG1  C N N 152 
ILE CG2  C N N 153 
ILE CD1  C N N 154 
ILE OXT  O N N 155 
ILE H    H N N 156 
ILE H2   H N N 157 
ILE HA   H N N 158 
ILE HB   H N N 159 
ILE HG12 H N N 160 
ILE HG13 H N N 161 
ILE HG21 H N N 162 
ILE HG22 H N N 163 
ILE HG23 H N N 164 
ILE HD11 H N N 165 
ILE HD12 H N N 166 
ILE HD13 H N N 167 
ILE HXT  H N N 168 
LEU N    N N N 169 
LEU CA   C N S 170 
LEU C    C N N 171 
LEU O    O N N 172 
LEU CB   C N N 173 
LEU CG   C N N 174 
LEU CD1  C N N 175 
LEU CD2  C N N 176 
LEU OXT  O N N 177 
LEU H    H N N 178 
LEU H2   H N N 179 
LEU HA   H N N 180 
LEU HB2  H N N 181 
LEU HB3  H N N 182 
LEU HG   H N N 183 
LEU HD11 H N N 184 
LEU HD12 H N N 185 
LEU HD13 H N N 186 
LEU HD21 H N N 187 
LEU HD22 H N N 188 
LEU HD23 H N N 189 
LEU HXT  H N N 190 
LYS N    N N N 191 
LYS CA   C N S 192 
LYS C    C N N 193 
LYS O    O N N 194 
LYS CB   C N N 195 
LYS CG   C N N 196 
LYS CD   C N N 197 
LYS CE   C N N 198 
LYS NZ   N N N 199 
LYS OXT  O N N 200 
LYS H    H N N 201 
LYS H2   H N N 202 
LYS HA   H N N 203 
LYS HB2  H N N 204 
LYS HB3  H N N 205 
LYS HG2  H N N 206 
LYS HG3  H N N 207 
LYS HD2  H N N 208 
LYS HD3  H N N 209 
LYS HE2  H N N 210 
LYS HE3  H N N 211 
LYS HZ1  H N N 212 
LYS HZ2  H N N 213 
LYS HZ3  H N N 214 
LYS HXT  H N N 215 
MET N    N N N 216 
MET CA   C N S 217 
MET C    C N N 218 
MET O    O N N 219 
MET CB   C N N 220 
MET CG   C N N 221 
MET SD   S N N 222 
MET CE   C N N 223 
MET OXT  O N N 224 
MET H    H N N 225 
MET H2   H N N 226 
MET HA   H N N 227 
MET HB2  H N N 228 
MET HB3  H N N 229 
MET HG2  H N N 230 
MET HG3  H N N 231 
MET HE1  H N N 232 
MET HE2  H N N 233 
MET HE3  H N N 234 
MET HXT  H N N 235 
PHE N    N N N 236 
PHE CA   C N S 237 
PHE C    C N N 238 
PHE O    O N N 239 
PHE CB   C N N 240 
PHE CG   C Y N 241 
PHE CD1  C Y N 242 
PHE CD2  C Y N 243 
PHE CE1  C Y N 244 
PHE CE2  C Y N 245 
PHE CZ   C Y N 246 
PHE OXT  O N N 247 
PHE H    H N N 248 
PHE H2   H N N 249 
PHE HA   H N N 250 
PHE HB2  H N N 251 
PHE HB3  H N N 252 
PHE HD1  H N N 253 
PHE HD2  H N N 254 
PHE HE1  H N N 255 
PHE HE2  H N N 256 
PHE HZ   H N N 257 
PHE HXT  H N N 258 
PRO N    N N N 259 
PRO CA   C N S 260 
PRO C    C N N 261 
PRO O    O N N 262 
PRO CB   C N N 263 
PRO CG   C N N 264 
PRO CD   C N N 265 
PRO OXT  O N N 266 
PRO H    H N N 267 
PRO HA   H N N 268 
PRO HB2  H N N 269 
PRO HB3  H N N 270 
PRO HG2  H N N 271 
PRO HG3  H N N 272 
PRO HD2  H N N 273 
PRO HD3  H N N 274 
PRO HXT  H N N 275 
SER N    N N N 276 
SER CA   C N S 277 
SER C    C N N 278 
SER O    O N N 279 
SER CB   C N N 280 
SER OG   O N N 281 
SER OXT  O N N 282 
SER H    H N N 283 
SER H2   H N N 284 
SER HA   H N N 285 
SER HB2  H N N 286 
SER HB3  H N N 287 
SER HG   H N N 288 
SER HXT  H N N 289 
SO4 S    S N N 290 
SO4 O1   O N N 291 
SO4 O2   O N N 292 
SO4 O3   O N N 293 
SO4 O4   O N N 294 
THR N    N N N 295 
THR CA   C N S 296 
THR C    C N N 297 
THR O    O N N 298 
THR CB   C N R 299 
THR OG1  O N N 300 
THR CG2  C N N 301 
THR OXT  O N N 302 
THR H    H N N 303 
THR H2   H N N 304 
THR HA   H N N 305 
THR HB   H N N 306 
THR HG1  H N N 307 
THR HG21 H N N 308 
THR HG22 H N N 309 
THR HG23 H N N 310 
THR HXT  H N N 311 
TRP N    N N N 312 
TRP CA   C N S 313 
TRP C    C N N 314 
TRP O    O N N 315 
TRP CB   C N N 316 
TRP CG   C Y N 317 
TRP CD1  C Y N 318 
TRP CD2  C Y N 319 
TRP NE1  N Y N 320 
TRP CE2  C Y N 321 
TRP CE3  C Y N 322 
TRP CZ2  C Y N 323 
TRP CZ3  C Y N 324 
TRP CH2  C Y N 325 
TRP OXT  O N N 326 
TRP H    H N N 327 
TRP H2   H N N 328 
TRP HA   H N N 329 
TRP HB2  H N N 330 
TRP HB3  H N N 331 
TRP HD1  H N N 332 
TRP HE1  H N N 333 
TRP HE3  H N N 334 
TRP HZ2  H N N 335 
TRP HZ3  H N N 336 
TRP HH2  H N N 337 
TRP HXT  H N N 338 
TYR N    N N N 339 
TYR CA   C N S 340 
TYR C    C N N 341 
TYR O    O N N 342 
TYR CB   C N N 343 
TYR CG   C Y N 344 
TYR CD1  C Y N 345 
TYR CD2  C Y N 346 
TYR CE1  C Y N 347 
TYR CE2  C Y N 348 
TYR CZ   C Y N 349 
TYR OH   O N N 350 
TYR OXT  O N N 351 
TYR H    H N N 352 
TYR H2   H N N 353 
TYR HA   H N N 354 
TYR HB2  H N N 355 
TYR HB3  H N N 356 
TYR HD1  H N N 357 
TYR HD2  H N N 358 
TYR HE1  H N N 359 
TYR HE2  H N N 360 
TYR HH   H N N 361 
TYR HXT  H N N 362 
VAL N    N N N 363 
VAL CA   C N S 364 
VAL C    C N N 365 
VAL O    O N N 366 
VAL CB   C N N 367 
VAL CG1  C N N 368 
VAL CG2  C N N 369 
VAL OXT  O N N 370 
VAL H    H N N 371 
VAL H2   H N N 372 
VAL HA   H N N 373 
VAL HB   H N N 374 
VAL HG11 H N N 375 
VAL HG12 H N N 376 
VAL HG13 H N N 377 
VAL HG21 H N N 378 
VAL HG22 H N N 379 
VAL HG23 H N N 380 
VAL HXT  H N N 381 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
HOH O   H1   sing N N 137 
HOH O   H2   sing N N 138 
ILE N   CA   sing N N 139 
ILE N   H    sing N N 140 
ILE N   H2   sing N N 141 
ILE CA  C    sing N N 142 
ILE CA  CB   sing N N 143 
ILE CA  HA   sing N N 144 
ILE C   O    doub N N 145 
ILE C   OXT  sing N N 146 
ILE CB  CG1  sing N N 147 
ILE CB  CG2  sing N N 148 
ILE CB  HB   sing N N 149 
ILE CG1 CD1  sing N N 150 
ILE CG1 HG12 sing N N 151 
ILE CG1 HG13 sing N N 152 
ILE CG2 HG21 sing N N 153 
ILE CG2 HG22 sing N N 154 
ILE CG2 HG23 sing N N 155 
ILE CD1 HD11 sing N N 156 
ILE CD1 HD12 sing N N 157 
ILE CD1 HD13 sing N N 158 
ILE OXT HXT  sing N N 159 
LEU N   CA   sing N N 160 
LEU N   H    sing N N 161 
LEU N   H2   sing N N 162 
LEU CA  C    sing N N 163 
LEU CA  CB   sing N N 164 
LEU CA  HA   sing N N 165 
LEU C   O    doub N N 166 
LEU C   OXT  sing N N 167 
LEU CB  CG   sing N N 168 
LEU CB  HB2  sing N N 169 
LEU CB  HB3  sing N N 170 
LEU CG  CD1  sing N N 171 
LEU CG  CD2  sing N N 172 
LEU CG  HG   sing N N 173 
LEU CD1 HD11 sing N N 174 
LEU CD1 HD12 sing N N 175 
LEU CD1 HD13 sing N N 176 
LEU CD2 HD21 sing N N 177 
LEU CD2 HD22 sing N N 178 
LEU CD2 HD23 sing N N 179 
LEU OXT HXT  sing N N 180 
LYS N   CA   sing N N 181 
LYS N   H    sing N N 182 
LYS N   H2   sing N N 183 
LYS CA  C    sing N N 184 
LYS CA  CB   sing N N 185 
LYS CA  HA   sing N N 186 
LYS C   O    doub N N 187 
LYS C   OXT  sing N N 188 
LYS CB  CG   sing N N 189 
LYS CB  HB2  sing N N 190 
LYS CB  HB3  sing N N 191 
LYS CG  CD   sing N N 192 
LYS CG  HG2  sing N N 193 
LYS CG  HG3  sing N N 194 
LYS CD  CE   sing N N 195 
LYS CD  HD2  sing N N 196 
LYS CD  HD3  sing N N 197 
LYS CE  NZ   sing N N 198 
LYS CE  HE2  sing N N 199 
LYS CE  HE3  sing N N 200 
LYS NZ  HZ1  sing N N 201 
LYS NZ  HZ2  sing N N 202 
LYS NZ  HZ3  sing N N 203 
LYS OXT HXT  sing N N 204 
MET N   CA   sing N N 205 
MET N   H    sing N N 206 
MET N   H2   sing N N 207 
MET CA  C    sing N N 208 
MET CA  CB   sing N N 209 
MET CA  HA   sing N N 210 
MET C   O    doub N N 211 
MET C   OXT  sing N N 212 
MET CB  CG   sing N N 213 
MET CB  HB2  sing N N 214 
MET CB  HB3  sing N N 215 
MET CG  SD   sing N N 216 
MET CG  HG2  sing N N 217 
MET CG  HG3  sing N N 218 
MET SD  CE   sing N N 219 
MET CE  HE1  sing N N 220 
MET CE  HE2  sing N N 221 
MET CE  HE3  sing N N 222 
MET OXT HXT  sing N N 223 
PHE N   CA   sing N N 224 
PHE N   H    sing N N 225 
PHE N   H2   sing N N 226 
PHE CA  C    sing N N 227 
PHE CA  CB   sing N N 228 
PHE CA  HA   sing N N 229 
PHE C   O    doub N N 230 
PHE C   OXT  sing N N 231 
PHE CB  CG   sing N N 232 
PHE CB  HB2  sing N N 233 
PHE CB  HB3  sing N N 234 
PHE CG  CD1  doub Y N 235 
PHE CG  CD2  sing Y N 236 
PHE CD1 CE1  sing Y N 237 
PHE CD1 HD1  sing N N 238 
PHE CD2 CE2  doub Y N 239 
PHE CD2 HD2  sing N N 240 
PHE CE1 CZ   doub Y N 241 
PHE CE1 HE1  sing N N 242 
PHE CE2 CZ   sing Y N 243 
PHE CE2 HE2  sing N N 244 
PHE CZ  HZ   sing N N 245 
PHE OXT HXT  sing N N 246 
PRO N   CA   sing N N 247 
PRO N   CD   sing N N 248 
PRO N   H    sing N N 249 
PRO CA  C    sing N N 250 
PRO CA  CB   sing N N 251 
PRO CA  HA   sing N N 252 
PRO C   O    doub N N 253 
PRO C   OXT  sing N N 254 
PRO CB  CG   sing N N 255 
PRO CB  HB2  sing N N 256 
PRO CB  HB3  sing N N 257 
PRO CG  CD   sing N N 258 
PRO CG  HG2  sing N N 259 
PRO CG  HG3  sing N N 260 
PRO CD  HD2  sing N N 261 
PRO CD  HD3  sing N N 262 
PRO OXT HXT  sing N N 263 
SER N   CA   sing N N 264 
SER N   H    sing N N 265 
SER N   H2   sing N N 266 
SER CA  C    sing N N 267 
SER CA  CB   sing N N 268 
SER CA  HA   sing N N 269 
SER C   O    doub N N 270 
SER C   OXT  sing N N 271 
SER CB  OG   sing N N 272 
SER CB  HB2  sing N N 273 
SER CB  HB3  sing N N 274 
SER OG  HG   sing N N 275 
SER OXT HXT  sing N N 276 
SO4 S   O1   doub N N 277 
SO4 S   O2   doub N N 278 
SO4 S   O3   sing N N 279 
SO4 S   O4   sing N N 280 
THR N   CA   sing N N 281 
THR N   H    sing N N 282 
THR N   H2   sing N N 283 
THR CA  C    sing N N 284 
THR CA  CB   sing N N 285 
THR CA  HA   sing N N 286 
THR C   O    doub N N 287 
THR C   OXT  sing N N 288 
THR CB  OG1  sing N N 289 
THR CB  CG2  sing N N 290 
THR CB  HB   sing N N 291 
THR OG1 HG1  sing N N 292 
THR CG2 HG21 sing N N 293 
THR CG2 HG22 sing N N 294 
THR CG2 HG23 sing N N 295 
THR OXT HXT  sing N N 296 
TRP N   CA   sing N N 297 
TRP N   H    sing N N 298 
TRP N   H2   sing N N 299 
TRP CA  C    sing N N 300 
TRP CA  CB   sing N N 301 
TRP CA  HA   sing N N 302 
TRP C   O    doub N N 303 
TRP C   OXT  sing N N 304 
TRP CB  CG   sing N N 305 
TRP CB  HB2  sing N N 306 
TRP CB  HB3  sing N N 307 
TRP CG  CD1  doub Y N 308 
TRP CG  CD2  sing Y N 309 
TRP CD1 NE1  sing Y N 310 
TRP CD1 HD1  sing N N 311 
TRP CD2 CE2  doub Y N 312 
TRP CD2 CE3  sing Y N 313 
TRP NE1 CE2  sing Y N 314 
TRP NE1 HE1  sing N N 315 
TRP CE2 CZ2  sing Y N 316 
TRP CE3 CZ3  doub Y N 317 
TRP CE3 HE3  sing N N 318 
TRP CZ2 CH2  doub Y N 319 
TRP CZ2 HZ2  sing N N 320 
TRP CZ3 CH2  sing Y N 321 
TRP CZ3 HZ3  sing N N 322 
TRP CH2 HH2  sing N N 323 
TRP OXT HXT  sing N N 324 
TYR N   CA   sing N N 325 
TYR N   H    sing N N 326 
TYR N   H2   sing N N 327 
TYR CA  C    sing N N 328 
TYR CA  CB   sing N N 329 
TYR CA  HA   sing N N 330 
TYR C   O    doub N N 331 
TYR C   OXT  sing N N 332 
TYR CB  CG   sing N N 333 
TYR CB  HB2  sing N N 334 
TYR CB  HB3  sing N N 335 
TYR CG  CD1  doub Y N 336 
TYR CG  CD2  sing Y N 337 
TYR CD1 CE1  sing Y N 338 
TYR CD1 HD1  sing N N 339 
TYR CD2 CE2  doub Y N 340 
TYR CD2 HD2  sing N N 341 
TYR CE1 CZ   doub Y N 342 
TYR CE1 HE1  sing N N 343 
TYR CE2 CZ   sing Y N 344 
TYR CE2 HE2  sing N N 345 
TYR CZ  OH   sing N N 346 
TYR OH  HH   sing N N 347 
TYR OXT HXT  sing N N 348 
VAL N   CA   sing N N 349 
VAL N   H    sing N N 350 
VAL N   H2   sing N N 351 
VAL CA  C    sing N N 352 
VAL CA  CB   sing N N 353 
VAL CA  HA   sing N N 354 
VAL C   O    doub N N 355 
VAL C   OXT  sing N N 356 
VAL CB  CG1  sing N N 357 
VAL CB  CG2  sing N N 358 
VAL CB  HB   sing N N 359 
VAL CG1 HG11 sing N N 360 
VAL CG1 HG12 sing N N 361 
VAL CG1 HG13 sing N N 362 
VAL CG2 HG21 sing N N 363 
VAL CG2 HG22 sing N N 364 
VAL CG2 HG23 sing N N 365 
VAL OXT HXT  sing N N 366 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   3MF8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NG5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016595 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009868 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007269 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . PRO A 1 1   ? 10.89418  18.05554  -17.58469 1.000 33.42163 ? 1   PRO A N   1 
ATOM   2    C CA  . PRO A 1 1   ? 9.53343   17.52438  -17.46082 1.000 28.03469 ? 1   PRO A CA  1 
ATOM   3    C C   . PRO A 1 1   ? 8.79402   18.03539  -16.24818 1.000 26.66250 ? 1   PRO A C   1 
ATOM   4    O O   . PRO A 1 1   ? 9.42551   18.54057  -15.31924 1.000 28.53481 ? 1   PRO A O   1 
ATOM   5    C CB  . PRO A 1 1   ? 9.76461   16.02566  -17.31409 1.000 22.66838 ? 1   PRO A CB  1 
ATOM   6    C CG  . PRO A 1 1   ? 11.14223  15.94595  -16.71262 1.000 22.30156 ? 1   PRO A CG  1 
ATOM   7    C CD  . PRO A 1 1   ? 11.89928  16.98672  -17.44534 1.000 26.22254 ? 1   PRO A CD  1 
ATOM   8    N N   . VAL A 1 2   ? 7.46989   17.90574  -16.26810 1.000 25.44426 ? 2   VAL A N   1 
ATOM   9    C CA  . VAL A 1 2   ? 6.64977   17.95244  -15.06353 1.000 28.75495 ? 2   VAL A CA  1 
ATOM   10   C C   . VAL A 1 2   ? 5.72706   16.74771  -15.09725 1.000 27.31609 ? 2   VAL A C   1 
ATOM   11   O O   . VAL A 1 2   ? 4.97297   16.56426  -16.06268 1.000 23.88522 ? 2   VAL A O   1 
ATOM   12   C CB  . VAL A 1 2   ? 5.83001   19.24310  -14.92386 1.000 30.09289 ? 2   VAL A CB  1 
ATOM   13   C CG1 . VAL A 1 2   ? 4.68914   19.00008  -13.96453 1.000 29.35495 ? 2   VAL A CG1 1 
ATOM   14   C CG2 . VAL A 1 2   ? 6.68725   20.34905  -14.38066 1.000 27.60316 ? 2   VAL A CG2 1 
ATOM   15   N N   . TYR A 1 3   ? 5.79887   15.92852  -14.05112 1.000 27.88812 ? 3   TYR A N   1 
ATOM   16   C CA  . TYR A 1 3   ? 4.96552   14.74926  -13.88298 1.000 26.36813 ? 3   TYR A CA  1 
ATOM   17   C C   . TYR A 1 3   ? 3.97643   15.02785  -12.76570 1.000 22.12494 ? 3   TYR A C   1 
ATOM   18   O O   . TYR A 1 3   ? 4.38167   15.30452  -11.63508 1.000 31.87714 ? 3   TYR A O   1 
ATOM   19   C CB  . TYR A 1 3   ? 5.81071   13.52804  -13.53106 1.000 23.24081 ? 3   TYR A CB  1 
ATOM   20   C CG  . TYR A 1 3   ? 6.68862   13.04032  -14.63964 1.000 20.69394 ? 3   TYR A CG  1 
ATOM   21   C CD1 . TYR A 1 3   ? 6.19619   12.13938  -15.57705 1.000 23.42363 ? 3   TYR A CD1 1 
ATOM   22   C CD2 . TYR A 1 3   ? 8.01428   13.44406  -14.74534 1.000 15.58949 ? 3   TYR A CD2 1 
ATOM   23   C CE1 . TYR A 1 3   ? 6.97863   11.66395  -16.58299 1.000 18.71589 ? 3   TYR A CE1 1 
ATOM   24   C CE2 . TYR A 1 3   ? 8.81437   12.96577  -15.76573 1.000 10.99339 ? 3   TYR A CE2 1 
ATOM   25   C CZ  . TYR A 1 3   ? 8.27682   12.08336  -16.68508 1.000 15.85162 ? 3   TYR A CZ  1 
ATOM   26   O OH  . TYR A 1 3   ? 9.01536   11.56611  -17.71824 1.000 18.31954 ? 3   TYR A OH  1 
ATOM   27   N N   . MET A 1 4   ? 2.69503   14.97634  -13.08352 1.000 19.34167 ? 4   MET A N   1 
ATOM   28   C CA  . MET A 1 4   ? 1.66975   14.88831  -12.06095 1.000 15.35897 ? 4   MET A CA  1 
ATOM   29   C C   . MET A 1 4   ? 1.48714   13.42226  -11.68430 1.000 22.67597 ? 4   MET A C   1 
ATOM   30   O O   . MET A 1 4   ? 1.42859   12.55734  -12.57010 1.000 19.45779 ? 4   MET A O   1 
ATOM   31   C CB  . MET A 1 4   ? 0.37640   15.49364  -12.58411 1.000 20.63569 ? 4   MET A CB  1 
ATOM   32   C CG  . MET A 1 4   ? 0.61201   16.78581  -13.37565 1.000 18.66239 ? 4   MET A CG  1 
ATOM   33   S SD  . MET A 1 4   ? 1.32604   18.08305  -12.32659 1.000 30.01304 ? 4   MET A SD  1 
ATOM   34   C CE  . MET A 1 4   ? -0.08835  18.41988  -11.26449 1.000 21.67908 ? 4   MET A CE  1 
ATOM   35   N N   . VAL A 1 5   ? 1.43757   13.13737  -10.37515 1.000 19.02733 ? 5   VAL A N   1 
ATOM   36   C CA  . VAL A 1 5   ? 1.30880   11.77130  -9.85798  1.000 19.97963 ? 5   VAL A CA  1 
ATOM   37   C C   . VAL A 1 5   ? 0.08631   11.70295  -8.95271  1.000 17.14744 ? 5   VAL A C   1 
ATOM   38   O O   . VAL A 1 5   ? 0.12480   12.11242  -7.78939  1.000 18.50476 ? 5   VAL A O   1 
ATOM   39   C CB  . VAL A 1 5   ? 2.56001   11.30030  -9.11060  1.000 20.05152 ? 5   VAL A CB  1 
ATOM   40   C CG1 . VAL A 1 5   ? 2.29723   9.94814   -8.55250  1.000 22.48703 ? 5   VAL A CG1 1 
ATOM   41   C CG2 . VAL A 1 5   ? 3.77564   11.25262  -10.04278 1.000 14.98998 ? 5   VAL A CG2 1 
ATOM   42   N N   . TYR A 1 6   ? -0.98532  11.14282  -9.46841  1.000 19.36431 ? 6   TYR A N   1 
ATOM   43   C CA  . TYR A 1 6   ? -2.24596  11.07324  -8.75142  1.000 22.72201 ? 6   TYR A CA  1 
ATOM   44   C C   . TYR A 1 6   ? -2.29461  9.76729   -7.96487  1.000 25.13689 ? 6   TYR A C   1 
ATOM   45   O O   . TYR A 1 6   ? -2.10524  8.67881   -8.52927  1.000 22.43159 ? 6   TYR A O   1 
ATOM   46   C CB  . TYR A 1 6   ? -3.40687  11.20248  -9.73364  1.000 19.96194 ? 6   TYR A CB  1 
ATOM   47   C CG  . TYR A 1 6   ? -3.32214  12.48176  -10.55149 1.000 19.29151 ? 6   TYR A CG  1 
ATOM   48   C CD1 . TYR A 1 6   ? -2.61284  12.52497  -11.76199 1.000 20.50743 ? 6   TYR A CD1 1 
ATOM   49   C CD2 . TYR A 1 6   ? -3.93710  13.64287  -10.11319 1.000 18.05813 ? 6   TYR A CD2 1 
ATOM   50   C CE1 . TYR A 1 6   ? -2.53334  13.69989  -12.52205 1.000 19.00449 ? 6   TYR A CE1 1 
ATOM   51   C CE2 . TYR A 1 6   ? -3.86202  14.81467  -10.84950 1.000 16.12949 ? 6   TYR A CE2 1 
ATOM   52   C CZ  . TYR A 1 6   ? -3.16044  14.84660  -12.05050 1.000 19.49489 ? 6   TYR A CZ  1 
ATOM   53   O OH  . TYR A 1 6   ? -3.09679  16.02368  -12.75584 1.000 21.71057 ? 6   TYR A OH  1 
ATOM   54   N N   . VAL A 1 7   ? -2.46899  9.89255   -6.64663  1.000 26.26502 ? 7   VAL A N   1 
ATOM   55   C CA  . VAL A 1 7   ? -2.43102  8.76809   -5.72129  1.000 23.00221 ? 7   VAL A CA  1 
ATOM   56   C C   . VAL A 1 7   ? -3.41729  9.05271   -4.60350  1.000 19.18953 ? 7   VAL A C   1 
ATOM   57   O O   . VAL A 1 7   ? -3.83707  10.19008  -4.38623  1.000 28.84724 ? 7   VAL A O   1 
ATOM   58   C CB  . VAL A 1 7   ? -1.01795  8.51864   -5.13323  1.000 24.46942 ? 7   VAL A CB  1 
ATOM   59   C CG1 . VAL A 1 7   ? 0.00910   8.31151   -6.23169  1.000 19.36613 ? 7   VAL A CG1 1 
ATOM   60   C CG2 . VAL A 1 7   ? -0.60633  9.64770   -4.22054  1.000 22.74253 ? 7   VAL A CG2 1 
ATOM   61   N N   . SER A 1 8   ? -3.78501  8.01817   -3.87627  1.000 23.42227 ? 8   SER A N   1 
ATOM   62   C CA  . SER A 1 8   ? -4.71103  8.22261   -2.77948  1.000 24.16397 ? 8   SER A CA  1 
ATOM   63   C C   . SER A 1 8   ? -3.95589  8.72520   -1.56041  1.000 27.00775 ? 8   SER A C   1 
ATOM   64   O O   . SER A 1 8   ? -2.78473  8.39169   -1.35710  1.000 24.60245 ? 8   SER A O   1 
ATOM   65   C CB  . SER A 1 8   ? -5.47121  6.94127   -2.46599  1.000 26.02056 ? 8   SER A CB  1 
ATOM   66   O OG  . SER A 1 8   ? -6.60831  6.86054   -3.30365  1.000 27.20247 ? 8   SER A OG  1 
ATOM   67   N N   . GLN A 1 9   ? -4.60951  9.61266   -0.81224  1.000 29.75188 ? 9   GLN A N   1 
ATOM   68   C CA  . GLN A 1 9   ? -4.16476  10.00658  0.51891   1.000 34.88405 ? 9   GLN A CA  1 
ATOM   69   C C   . GLN A 1 9   ? -3.76453  8.78694   1.34031   1.000 27.69744 ? 9   GLN A C   1 
ATOM   70   O O   . GLN A 1 9   ? -4.49840  7.79960   1.39871   1.000 31.98590 ? 9   GLN A O   1 
ATOM   71   C CB  . GLN A 1 9   ? -5.29753  10.76388  1.21072   1.000 39.65906 ? 9   GLN A CB  1 
ATOM   72   C CG  . GLN A 1 9   ? -5.16618  10.89573  2.70520   1.000 43.31333 ? 9   GLN A CG  1 
ATOM   73   C CD  . GLN A 1 9   ? -4.24504  12.02812  3.09804   1.000 48.68817 ? 9   GLN A CD  1 
ATOM   74   O OE1 . GLN A 1 9   ? -3.05173  12.00379  2.79040   1.000 47.03152 ? 9   GLN A OE1 1 
ATOM   75   N NE2 . GLN A 1 9   ? -4.79519  13.03722  3.77437   1.000 49.53516 ? 9   GLN A NE2 1 
ATOM   76   N N   . ASP A 1 10  ? -2.57233  8.84190   1.92773   1.000 32.09205 ? 10  ASP A N   1 
ATOM   77   C CA  . ASP A 1 10  ? -1.98267  7.85915   2.83507   1.000 36.19875 ? 10  ASP A CA  1 
ATOM   78   C C   . ASP A 1 10  ? -1.35328  6.68705   2.08974   1.000 34.25632 ? 10  ASP A C   1 
ATOM   79   O O   . ASP A 1 10  ? -0.61842  5.90787   2.70735   1.000 34.63329 ? 10  ASP A O   1 
ATOM   80   C CB  . ASP A 1 10  ? -2.98078  7.30091   3.87537   1.000 45.69333 ? 10  ASP A CB  1 
ATOM   81   C CG  . ASP A 1 10  ? -3.67130  8.39889   4.68760   1.000 46.01155 ? 10  ASP A CG  1 
ATOM   82   O OD1 . ASP A 1 10  ? -2.99882  9.37747   5.08218   1.000 47.04857 ? 10  ASP A OD1 1 
ATOM   83   O OD2 . ASP A 1 10  ? -4.89529  8.28554   4.92784   1.000 54.65806 ? 10  ASP A OD2 1 
ATOM   84   N N   . ARG A 1 11  ? -1.59577  6.53678   0.78644   1.000 27.93961 ? 11  ARG A N   1 
ATOM   85   C CA  . ARG A 1 11  ? -1.07883  5.37885   0.07750   1.000 27.45956 ? 11  ARG A CA  1 
ATOM   86   C C   . ARG A 1 11  ? 0.43719   5.33481   0.12093   1.000 26.40684 ? 11  ARG A C   1 
ATOM   87   O O   . ARG A 1 11  ? 1.02861   4.26784   0.31401   1.000 26.72278 ? 11  ARG A O   1 
ATOM   88   C CB  . ARG A 1 11  ? -1.55824  5.37780   -1.36898  1.000 29.73937 ? 11  ARG A CB  1 
ATOM   89   C CG  . ARG A 1 11  ? -1.24358  4.07145   -2.03171  1.000 27.05710 ? 11  ARG A CG  1 
ATOM   90   C CD  . ARG A 1 11  ? -1.54044  2.92433   -1.06735  1.000 31.09326 ? 11  ARG A CD  1 
ATOM   91   N NE  . ARG A 1 11  ? -1.14478  1.63598   -1.61896  1.000 32.80669 ? 11  ARG A NE  1 
ATOM   92   C CZ  . ARG A 1 11  ? 0.07854   1.13357   -1.53604  1.000 39.10744 ? 11  ARG A CZ  1 
ATOM   93   N NH1 . ARG A 1 11  ? 1.04891   1.77621   -0.90560  1.000 39.17942 ? 11  ARG A NH1 1 
ATOM   94   N NH2 . ARG A 1 11  ? 0.33790   -0.03796  -2.10956  1.000 40.97451 ? 11  ARG A NH2 1 
ATOM   95   N N   . LEU A 1 12  ? 1.08013   6.48074   -0.05808  1.000 32.66919 ? 12  LEU A N   1 
ATOM   96   C CA  . LEU A 1 12  ? 2.52956   6.57976   -0.08684  1.000 25.17457 ? 12  LEU A CA  1 
ATOM   97   C C   . LEU A 1 12  ? 2.97819   7.34866   1.14373   1.000 25.99608 ? 12  LEU A C   1 
ATOM   98   O O   . LEU A 1 12  ? 2.59432   8.50663   1.33429   1.000 28.60902 ? 12  LEU A O   1 
ATOM   99   C CB  . LEU A 1 12  ? 3.01782   7.27434   -1.35928  1.000 26.75834 ? 12  LEU A CB  1 
ATOM   100  C CG  . LEU A 1 12  ? 2.47184   6.80255   -2.71342  1.000 26.91749 ? 12  LEU A CG  1 
ATOM   101  C CD1 . LEU A 1 12  ? 3.06485   7.60610   -3.89538  1.000 24.86791 ? 12  LEU A CD1 1 
ATOM   102  C CD2 . LEU A 1 12  ? 2.70174   5.32476   -2.89171  1.000 26.93606 ? 12  LEU A CD2 1 
ATOM   103  N N   . THR A 1 13  ? 3.77975   6.70230   1.97285   1.000 24.27724 ? 13  THR A N   1 
ATOM   104  C CA  . THR A 1 13  ? 4.49680   7.39906   3.01515   1.000 34.51183 ? 13  THR A CA  1 
ATOM   105  C C   . THR A 1 13  ? 5.46565   8.41270   2.40096   1.000 34.20665 ? 13  THR A C   1 
ATOM   106  O O   . THR A 1 13  ? 5.85759   8.28176   1.24516   1.000 33.06108 ? 13  THR A O   1 
ATOM   107  C CB  . THR A 1 13  ? 5.26191   6.39721   3.86134   1.000 35.46494 ? 13  THR A CB  1 
ATOM   108  O OG1 . THR A 1 13  ? 6.20458   5.72488   3.01798   1.000 30.16808 ? 13  THR A OG1 1 
ATOM   109  C CG2 . THR A 1 13  ? 4.29498   5.37572   4.46520   1.000 29.74936 ? 13  THR A CG2 1 
ATOM   110  N N   . PRO A 1 14  ? 5.85324   9.44507   3.15583   1.000 32.52088 ? 14  PRO A N   1 
ATOM   111  C CA  . PRO A 1 14  ? 6.85261   10.38897  2.63636   1.000 30.26279 ? 14  PRO A CA  1 
ATOM   112  C C   . PRO A 1 14  ? 8.10733   9.72891   2.08816   1.000 24.90215 ? 14  PRO A C   1 
ATOM   113  O O   . PRO A 1 14  ? 8.57087   10.10337  1.00940   1.000 37.20298 ? 14  PRO A O   1 
ATOM   114  C CB  . PRO A 1 14  ? 7.14552   11.26265  3.86256   1.000 32.45861 ? 14  PRO A CB  1 
ATOM   115  C CG  . PRO A 1 14  ? 5.86087   11.30682  4.56232   1.000 29.64920 ? 14  PRO A CG  1 
ATOM   116  C CD  . PRO A 1 14  ? 5.30653   9.90101   4.44308   1.000 29.23185 ? 14  PRO A CD  1 
ATOM   117  N N   . SER A 1 15  ? 8.67099   8.75653   2.79353   1.000 31.20687 ? 15  SER A N   1 
ATOM   118  C CA  . SER A 1 15  ? 9.82134   8.03571   2.26320   1.000 33.44831 ? 15  SER A CA  1 
ATOM   119  C C   . SER A 1 15  ? 9.47745   7.34083   0.94866   1.000 36.38999 ? 15  SER A C   1 
ATOM   120  O O   . SER A 1 15  ? 10.35096  7.16252   0.08736   1.000 28.89078 ? 15  SER A O   1 
ATOM   121  C CB  . SER A 1 15  ? 10.31154  7.02488   3.29698   1.000 29.23583 ? 15  SER A CB  1 
ATOM   122  O OG  . SER A 1 15  ? 11.68054  6.71993   3.13074   1.000 29.02485 ? 15  SER A OG  1 
ATOM   123  N N   . ALA A 1 16  ? 8.20699   6.96079   0.77638   1.000 31.71186 ? 16  ALA A N   1 
ATOM   124  C CA  . ALA A 1 16  ? 7.77073   6.31291   -0.45372  1.000 30.18131 ? 16  ALA A CA  1 
ATOM   125  C C   . ALA A 1 16  ? 7.69427   7.31465   -1.59697  1.000 29.15665 ? 16  ALA A C   1 
ATOM   126  O O   . ALA A 1 16  ? 8.20345   7.05206   -2.69186  1.000 28.85739 ? 16  ALA A O   1 
ATOM   127  C CB  . ALA A 1 16  ? 6.42026   5.62381   -0.23819  1.000 24.85886 ? 16  ALA A CB  1 
ATOM   128  N N   . LYS A 1 17  ? 7.07370   8.47640   -1.35415  1.000 33.32555 ? 17  LYS A N   1 
ATOM   129  C CA  . LYS A 1 17  ? 7.06658   9.55852   -2.34335  1.000 31.46525 ? 17  LYS A CA  1 
ATOM   130  C C   . LYS A 1 17  ? 8.46990   9.89048   -2.82848  1.000 31.70163 ? 17  LYS A C   1 
ATOM   131  O O   . LYS A 1 17  ? 8.70339   10.04590  -4.03238  1.000 36.02006 ? 17  LYS A O   1 
ATOM   132  C CB  . LYS A 1 17  ? 6.42567   10.81503  -1.76128  1.000 31.37871 ? 17  LYS A CB  1 
ATOM   133  C CG  . LYS A 1 17  ? 4.93554   10.72471  -1.53185  1.000 33.09581 ? 17  LYS A CG  1 
ATOM   134  C CD  . LYS A 1 17  ? 4.42089   12.04855  -1.01654  1.000 30.37591 ? 17  LYS A CD  1 
ATOM   135  C CE  . LYS A 1 17  ? 3.35081   11.83493  0.02575   1.000 34.06024 ? 17  LYS A CE  1 
ATOM   136  N NZ  . LYS A 1 17  ? 3.35709   12.94914  1.02110   1.000 34.97729 ? 17  LYS A NZ  1 
ATOM   137  N N   . HIS A 1 18  ? 9.41657   10.03395  -1.90054  1.000 35.45972 ? 18  HIS A N   1 
ATOM   138  C CA  . HIS A 1 18  ? 10.78609  10.30885  -2.31629  1.000 34.44245 ? 18  HIS A CA  1 
ATOM   139  C C   . HIS A 1 18  ? 11.32187  9.19518   -3.20147  1.000 32.93196 ? 18  HIS A C   1 
ATOM   140  O O   . HIS A 1 18  ? 11.99490  9.46182   -4.20170  1.000 28.65089 ? 18  HIS A O   1 
ATOM   141  C CB  . HIS A 1 18  ? 11.70307  10.50084  -1.10697  1.000 32.70522 ? 18  HIS A CB  1 
ATOM   142  C CG  . HIS A 1 18  ? 13.07403  10.98558  -1.47311  1.000 36.37167 ? 18  HIS A CG  1 
ATOM   143  N ND1 . HIS A 1 18  ? 13.97479  10.21504  -2.17516  1.000 39.43061 ? 18  HIS A ND1 1 
ATOM   144  C CD2 . HIS A 1 18  ? 13.68761  12.17310  -1.25747  1.000 34.81677 ? 18  HIS A CD2 1 
ATOM   145  C CE1 . HIS A 1 18  ? 15.08653  10.90116  -2.36742  1.000 33.99643 ? 18  HIS A CE1 1 
ATOM   146  N NE2 . HIS A 1 18  ? 14.93791  12.09255  -1.81986  1.000 30.61398 ? 18  HIS A NE2 1 
ATOM   147  N N   . ALA A 1 19  ? 11.05320  7.93572   -2.84198  1.000 32.33062 ? 19  ALA A N   1 
ATOM   148  C CA  . ALA A 1 19  ? 11.61084  6.83900   -3.62996  1.000 32.79380 ? 19  ALA A CA  1 
ATOM   149  C C   . ALA A 1 19  ? 11.01284  6.81516   -5.03856  1.000 30.86583 ? 19  ALA A C   1 
ATOM   150  O O   . ALA A 1 19  ? 11.72224  6.54816   -6.02116  1.000 23.36419 ? 19  ALA A O   1 
ATOM   151  C CB  . ALA A 1 19  ? 11.39264  5.50825   -2.90210  1.000 26.23953 ? 19  ALA A CB  1 
ATOM   152  N N   . VAL A 1 20  ? 9.71927   7.13988   -5.14982  1.000 28.50971 ? 20  VAL A N   1 
ATOM   153  C CA  . VAL A 1 20  ? 9.00449   7.07590   -6.42260  1.000 27.50922 ? 20  VAL A CA  1 
ATOM   154  C C   . VAL A 1 20  ? 9.35619   8.26629   -7.30825  1.000 27.98555 ? 20  VAL A C   1 
ATOM   155  O O   . VAL A 1 20  ? 9.66017   8.10171   -8.49654  1.000 28.23801 ? 20  VAL A O   1 
ATOM   156  C CB  . VAL A 1 20  ? 7.48716   6.97684   -6.16768  1.000 26.18419 ? 20  VAL A CB  1 
ATOM   157  C CG1 . VAL A 1 20  ? 6.69581   7.57010   -7.32914  1.000 19.14960 ? 20  VAL A CG1 1 
ATOM   158  C CG2 . VAL A 1 20  ? 7.09634   5.53300   -5.92675  1.000 16.24783 ? 20  VAL A CG2 1 
ATOM   159  N N   . ALA A 1 21  ? 9.31890   9.47883   -6.74399  1.000 29.92886 ? 21  ALA A N   1 
ATOM   160  C CA  . ALA A 1 21  ? 9.86221   10.64827  -7.43282  1.000 27.03765 ? 21  ALA A CA  1 
ATOM   161  C C   . ALA A 1 21  ? 11.28968  10.39756  -7.89779  1.000 24.54733 ? 21  ALA A C   1 
ATOM   162  O O   . ALA A 1 21  ? 11.68228  10.83936  -8.98022  1.000 29.86803 ? 21  ALA A O   1 
ATOM   163  C CB  . ALA A 1 21  ? 9.80314   11.88123  -6.51780  1.000 20.17340 ? 21  ALA A CB  1 
ATOM   164  N N   . LYS A 1 22  ? 12.07387  9.66375   -7.11003  1.000 19.28144 ? 22  LYS A N   1 
ATOM   165  C CA  . LYS A 1 22  ? 13.44377  9.37117   -7.51804  1.000 24.06370 ? 22  LYS A CA  1 
ATOM   166  C C   . LYS A 1 22  ? 13.50460  8.31093   -8.61490  1.000 29.60203 ? 22  LYS A C   1 
ATOM   167  O O   . LYS A 1 22  ? 14.40216  8.35992   -9.46288  1.000 26.77233 ? 22  LYS A O   1 
ATOM   168  C CB  . LYS A 1 22  ? 14.26420  8.92796   -6.31387  1.000 35.13527 ? 22  LYS A CB  1 
ATOM   169  C CG  . LYS A 1 22  ? 15.67342  8.47042   -6.64661  1.000 38.91685 ? 22  LYS A CG  1 
ATOM   170  C CD  . LYS A 1 22  ? 16.59913  9.67028   -6.91863  1.000 46.92741 ? 22  LYS A CD  1 
ATOM   171  C CE  . LYS A 1 22  ? 18.07674  9.27134   -6.95933  1.000 54.00382 ? 22  LYS A CE  1 
ATOM   172  N NZ  . LYS A 1 22  ? 18.75222  9.31923   -5.62563  1.000 55.82887 ? 22  LYS A NZ  1 
ATOM   173  N N   . ALA A 1 23  ? 12.58238  7.33916   -8.61213  1.000 27.39523 ? 23  ALA A N   1 
ATOM   174  C CA  . ALA A 1 23  ? 12.51148  6.38871   -9.71997  1.000 22.41134 ? 23  ALA A CA  1 
ATOM   175  C C   . ALA A 1 23  ? 12.21822  7.10595   -11.03602 1.000 26.54523 ? 23  ALA A C   1 
ATOM   176  O O   . ALA A 1 23  ? 12.94510  6.93779   -12.02582 1.000 22.18543 ? 23  ALA A O   1 
ATOM   177  C CB  . ALA A 1 23  ? 11.44186  5.33414   -9.44907  1.000 25.37321 ? 23  ALA A CB  1 
ATOM   178  N N   . ILE A 1 24  ? 11.15441  7.92223   -11.04299 1.000 22.52813 ? 24  ILE A N   1 
ATOM   179  C CA  . ILE A 1 24  ? 10.76069  8.70756   -12.21245 1.000 25.30874 ? 24  ILE A CA  1 
ATOM   180  C C   . ILE A 1 24  ? 11.87971  9.64726   -12.62867 1.000 20.93773 ? 24  ILE A C   1 
ATOM   181  O O   . ILE A 1 24  ? 12.20822  9.75781   -13.81342 1.000 20.19767 ? 24  ILE A O   1 
ATOM   182  C CB  . ILE A 1 24  ? 9.46593   9.48979   -11.92295 1.000 23.63535 ? 24  ILE A CB  1 
ATOM   183  C CG1 . ILE A 1 24  ? 8.27276   8.54908   -11.81119 1.000 18.46925 ? 24  ILE A CG1 1 
ATOM   184  C CG2 . ILE A 1 24  ? 9.20242   10.49756  -13.01764 1.000 26.45103 ? 24  ILE A CG2 1 
ATOM   185  C CD1 . ILE A 1 24  ? 7.24655   9.02509   -10.83230 1.000 24.02617 ? 24  ILE A CD1 1 
ATOM   186  N N   . THR A 1 25  ? 12.47709  10.34253  -11.65791 1.000 22.00459 ? 25  THR A N   1 
ATOM   187  C CA  . THR A 1 25  ? 13.58294  11.24652  -11.96485 1.000 23.88086 ? 25  THR A CA  1 
ATOM   188  C C   . THR A 1 25  ? 14.76148  10.50650  -12.58839 1.000 26.47556 ? 25  THR A C   1 
ATOM   189  O O   . THR A 1 25  ? 15.34941  10.97422  -13.57296 1.000 27.34261 ? 25  THR A O   1 
ATOM   190  C CB  . THR A 1 25  ? 14.02126  11.98084  -10.70616 1.000 26.68132 ? 25  THR A CB  1 
ATOM   191  O OG1 . THR A 1 25  ? 13.35491  13.24925  -10.63643 1.000 27.32934 ? 25  THR A OG1 1 
ATOM   192  C CG2 . THR A 1 25  ? 15.52887  12.17102  -10.69236 1.000 31.24814 ? 25  THR A CG2 1 
ATOM   193  N N   . ASP A 1 26  ? 15.11967  9.34782   -12.03632 1.000 25.53322 ? 26  ASP A N   1 
ATOM   194  C CA  . ASP A 1 26  ? 16.19341  8.55810   -12.63363 1.000 32.63644 ? 26  ASP A CA  1 
ATOM   195  C C   . ASP A 1 26  ? 15.81167  8.06135   -14.02441 1.000 25.19122 ? 26  ASP A C   1 
ATOM   196  O O   . ASP A 1 26  ? 16.66834  7.97461   -14.91093 1.000 26.00269 ? 26  ASP A O   1 
ATOM   197  C CB  . ASP A 1 26  ? 16.55975  7.38415   -11.72027 1.000 25.63221 ? 26  ASP A CB  1 
ATOM   198  C CG  . ASP A 1 26  ? 17.32370  7.83134   -10.48207 1.000 39.58795 ? 26  ASP A CG  1 
ATOM   199  O OD1 . ASP A 1 26  ? 18.30703  8.58965   -10.64191 1.000 29.62985 ? 26  ASP A OD1 1 
ATOM   200  O OD2 . ASP A 1 26  ? 16.93488  7.43044   -9.35249  1.000 41.92285 ? 26  ASP A OD2 1 
ATOM   201  N N   . ALA A 1 27  ? 14.53843  7.72327   -14.22238 1.000 24.89594 ? 27  ALA A N   1 
ATOM   202  C CA  . ALA A 1 27  ? 14.05890  7.31301   -15.53780 1.000 25.15845 ? 27  ALA A CA  1 
ATOM   203  C C   . ALA A 1 27  ? 14.30143  8.40138   -16.57894 1.000 22.82662 ? 27  ALA A C   1 
ATOM   204  O O   . ALA A 1 27  ? 14.90851  8.15587   -17.63414 1.000 25.54745 ? 27  ALA A O   1 
ATOM   205  C CB  . ALA A 1 27  ? 12.57235  6.97299   -15.44289 1.000 21.31580 ? 27  ALA A CB  1 
ATOM   206  N N   . HIS A 1 28  ? 13.84888  9.61786   -16.28383 1.000 23.22641 ? 28  HIS A N   1 
ATOM   207  C CA  . HIS A 1 28  ? 13.88226  10.69526  -17.26379 1.000 23.06484 ? 28  HIS A CA  1 
ATOM   208  C C   . HIS A 1 28  ? 15.31065  11.11977  -17.57710 1.000 29.92353 ? 28  HIS A C   1 
ATOM   209  O O   . HIS A 1 28  ? 15.69816  11.20215  -18.75484 1.000 29.29816 ? 28  HIS A O   1 
ATOM   210  C CB  . HIS A 1 28  ? 13.07144  11.88112  -16.76243 1.000 23.97477 ? 28  HIS A CB  1 
ATOM   211  C CG  . HIS A 1 28  ? 12.62216  12.78617  -17.85676 1.000 27.15603 ? 28  HIS A CG  1 
ATOM   212  N ND1 . HIS A 1 28  ? 11.41209  12.63188  -18.49397 1.000 30.95963 ? 28  HIS A ND1 1 
ATOM   213  C CD2 . HIS A 1 28  ? 13.23813  13.82740  -18.46321 1.000 28.82120 ? 28  HIS A CD2 1 
ATOM   214  C CE1 . HIS A 1 28  ? 11.28759  13.55459  -19.42892 1.000 27.28433 ? 28  HIS A CE1 1 
ATOM   215  N NE2 . HIS A 1 28  ? 12.38148  14.29455  -19.42949 1.000 32.56088 ? 28  HIS A NE2 1 
ATOM   216  N N   . ARG A 1 29  ? 16.10429  11.41145  -16.53868 1.000 26.05456 ? 29  ARG A N   1 
ATOM   217  C CA  . ARG A 1 29  ? 17.52085  11.70548  -16.74950 1.000 31.33214 ? 29  ARG A CA  1 
ATOM   218  C C   . ARG A 1 29  ? 18.18896  10.58737  -17.54015 1.000 32.53027 ? 29  ARG A C   1 
ATOM   219  O O   . ARG A 1 29  ? 18.89546  10.84162  -18.52443 1.000 38.53911 ? 29  ARG A O   1 
ATOM   220  C CB  . ARG A 1 29  ? 18.23610  11.91234  -15.40379 1.000 32.41798 ? 29  ARG A CB  1 
ATOM   221  C CG  . ARG A 1 29  ? 19.58998  12.65208  -15.47948 1.000 33.44714 ? 29  ARG A CG  1 
ATOM   222  C CD  . ARG A 1 29  ? 20.77150  11.76538  -15.87850 1.000 36.49825 ? 29  ARG A CD  1 
ATOM   223  N NE  . ARG A 1 29  ? 21.38433  11.10907  -14.72561 1.000 53.25765 ? 29  ARG A NE  1 
ATOM   224  C CZ  . ARG A 1 29  ? 22.37784  10.22826  -14.79004 1.000 58.35676 ? 29  ARG A CZ  1 
ATOM   225  N NH1 . ARG A 1 29  ? 22.91071  9.86545   -15.94686 1.000 64.87754 ? 29  ARG A NH1 1 
ATOM   226  N NH2 . ARG A 1 29  ? 22.84388  9.69122   -13.66504 1.000 52.58237 ? 29  ARG A NH2 1 
ATOM   227  N N   . GLY A 1 30  ? 17.94017  9.33618   -17.14247 1.000 24.17978 ? 30  GLY A N   1 
ATOM   228  C CA  . GLY A 1 30  ? 18.67207  8.22252   -17.72928 1.000 28.69097 ? 30  GLY A CA  1 
ATOM   229  C C   . GLY A 1 30  ? 18.46260  8.05344   -19.22639 1.000 25.97549 ? 30  GLY A C   1 
ATOM   230  O O   . GLY A 1 30  ? 19.38765  7.67908   -19.95160 1.000 24.61298 ? 30  GLY A O   1 
ATOM   231  N N   . LEU A 1 31  ? 17.24453  8.29794   -19.71224 1.000 28.70379 ? 31  LEU A N   1 
ATOM   232  C CA  . LEU A 1 31  ? 16.94740  7.99827   -21.10570 1.000 21.60405 ? 31  LEU A CA  1 
ATOM   233  C C   . LEU A 1 31  ? 16.85827  9.23197   -22.00198 1.000 25.17750 ? 31  LEU A C   1 
ATOM   234  O O   . LEU A 1 31  ? 17.00736  9.09798   -23.22295 1.000 28.42292 ? 31  LEU A O   1 
ATOM   235  C CB  . LEU A 1 31  ? 15.64997  7.17965   -21.19953 1.000 24.39462 ? 31  LEU A CB  1 
ATOM   236  C CG  . LEU A 1 31  ? 15.80475  5.65693   -21.00491 1.000 19.48525 ? 31  LEU A CG  1 
ATOM   237  C CD1 . LEU A 1 31  ? 14.60489  5.05170   -20.31723 1.000 14.49635 ? 31  LEU A CD1 1 
ATOM   238  C CD2 . LEU A 1 31  ? 16.02486  4.96044   -22.33977 1.000 20.88967 ? 31  LEU A CD2 1 
ATOM   239  N N   . THR A 1 32  ? 16.63972  10.42283  -21.44285 1.000 28.24083 ? 32  THR A N   1 
ATOM   240  C CA  . THR A 1 32  ? 16.57924  11.64298  -22.24288 1.000 28.99786 ? 32  THR A CA  1 
ATOM   241  C C   . THR A 1 32  ? 17.82676  12.51355  -22.13083 1.000 34.22693 ? 32  THR A C   1 
ATOM   242  O O   . THR A 1 32  ? 18.05156  13.35503  -23.00545 1.000 27.95536 ? 32  THR A O   1 
ATOM   243  C CB  . THR A 1 32  ? 15.36459  12.49864  -21.84305 1.000 32.58088 ? 32  THR A CB  1 
ATOM   244  O OG1 . THR A 1 32  ? 15.57433  13.05168  -20.53429 1.000 31.68391 ? 32  THR A OG1 1 
ATOM   245  C CG2 . THR A 1 32  ? 14.08677  11.67472  -21.83860 1.000 30.70748 ? 32  THR A CG2 1 
ATOM   246  N N   . GLY A 1 33  ? 18.62875  12.34533  -21.07883 1.000 39.12123 ? 33  GLY A N   1 
ATOM   247  C CA  . GLY A 1 33  ? 19.74258  13.22982  -20.80849 1.000 30.86784 ? 33  GLY A CA  1 
ATOM   248  C C   . GLY A 1 33  ? 19.37983  14.53924  -20.13721 1.000 36.81850 ? 33  GLY A C   1 
ATOM   249  O O   . GLY A 1 33  ? 20.27161  15.36800  -19.92031 1.000 37.25387 ? 33  GLY A O   1 
ATOM   250  N N   . THR A 1 34  ? 18.10874  14.76566  -19.80865 1.000 32.59610 ? 34  THR A N   1 
ATOM   251  C CA  . THR A 1 34  ? 17.73048  15.98811  -19.10939 1.000 36.84629 ? 34  THR A CA  1 
ATOM   252  C C   . THR A 1 34  ? 18.27247  15.95347  -17.68112 1.000 41.75612 ? 34  THR A C   1 
ATOM   253  O O   . THR A 1 34  ? 18.04881  14.98193  -16.95377 1.000 35.73911 ? 34  THR A O   1 
ATOM   254  C CB  . THR A 1 34  ? 16.20252  16.15740  -19.09078 1.000 37.00430 ? 34  THR A CB  1 
ATOM   255  O OG1 . THR A 1 34  ? 15.69788  16.35637  -20.42217 1.000 32.53556 ? 34  THR A OG1 1 
ATOM   256  C CG2 . THR A 1 34  ? 15.80719  17.34181  -18.22613 1.000 29.47394 ? 34  THR A CG2 1 
ATOM   257  N N   . GLN A 1 35  ? 18.98246  17.01481  -17.27671 1.000 35.30756 ? 35  GLN A N   1 
ATOM   258  C CA  . GLN A 1 35  ? 19.52390  17.07047  -15.92222 1.000 43.71030 ? 35  GLN A CA  1 
ATOM   259  C C   . GLN A 1 35  ? 18.42253  16.88501  -14.87998 1.000 34.58504 ? 35  GLN A C   1 
ATOM   260  O O   . GLN A 1 35  ? 17.29759  17.36487  -15.04873 1.000 25.62124 ? 35  GLN A O   1 
ATOM   261  C CB  . GLN A 1 35  ? 20.23894  18.40247  -15.67027 1.000 43.02506 ? 35  GLN A CB  1 
ATOM   262  C CG  . GLN A 1 35  ? 21.28688  18.77650  -16.69980 1.000 43.77022 ? 35  GLN A CG  1 
ATOM   263  C CD  . GLN A 1 35  ? 20.75641  19.78703  -17.68342 1.000 44.34638 ? 35  GLN A CD  1 
ATOM   264  O OE1 . GLN A 1 35  ? 19.54759  19.89418  -17.86632 1.000 45.83285 ? 35  GLN A OE1 1 
ATOM   265  N NE2 . GLN A 1 35  ? 21.65042  20.54572  -18.31294 1.000 39.87549 ? 35  GLN A NE2 1 
ATOM   266  N N   . HIS A 1 36  ? 18.77149  16.19092  -13.78907 1.000 36.24414 ? 36  HIS A N   1 
ATOM   267  C CA  . HIS A 1 36  ? 17.84839  15.95061  -12.68346 1.000 31.03511 ? 36  HIS A CA  1 
ATOM   268  C C   . HIS A 1 36  ? 17.02905  17.18452  -12.33053 1.000 31.04851 ? 36  HIS A C   1 
ATOM   269  O O   . HIS A 1 36  ? 15.80813  17.10677  -12.17283 1.000 28.61037 ? 36  HIS A O   1 
ATOM   270  C CB  . HIS A 1 36  ? 18.61658  15.48542  -11.43960 1.000 34.87808 ? 36  HIS A CB  1 
ATOM   271  C CG  . HIS A 1 36  ? 19.32542  14.17790  -11.60399 1.000 34.53098 ? 36  HIS A CG  1 
ATOM   272  N ND1 . HIS A 1 36  ? 20.66328  14.09348  -11.92624 1.000 46.04313 ? 36  HIS A ND1 1 
ATOM   273  C CD2 . HIS A 1 36  ? 18.89184  12.90380  -11.46342 1.000 31.64492 ? 36  HIS A CD2 1 
ATOM   274  C CE1 . HIS A 1 36  ? 21.02029  12.82286  -11.98856 1.000 43.45957 ? 36  HIS A CE1 1 
ATOM   275  N NE2 . HIS A 1 36  ? 19.96237  12.08067  -11.71614 1.000 37.59354 ? 36  HIS A NE2 1 
ATOM   276  N N   . PHE A 1 37  ? 17.68108  18.34671  -12.22608 1.000 31.58619 ? 37  PHE A N   1 
ATOM   277  C CA  . PHE A 1 37  ? 17.01022  19.48133  -11.59924 1.000 35.09387 ? 37  PHE A CA  1 
ATOM   278  C C   . PHE A 1 37  ? 15.86808  20.04953  -12.43950 1.000 35.31168 ? 37  PHE A C   1 
ATOM   279  O O   . PHE A 1 37  ? 15.06962  20.82904  -11.90654 1.000 27.78843 ? 37  PHE A O   1 
ATOM   280  C CB  . PHE A 1 37  ? 18.01636  20.58930  -11.24499 1.000 33.38498 ? 37  PHE A CB  1 
ATOM   281  C CG  . PHE A 1 37  ? 19.00830  20.91737  -12.34048 1.000 39.45792 ? 37  PHE A CG  1 
ATOM   282  C CD1 . PHE A 1 37  ? 18.59121  21.32276  -13.60424 1.000 40.11323 ? 37  PHE A CD1 1 
ATOM   283  C CD2 . PHE A 1 37  ? 20.37055  20.86277  -12.08383 1.000 41.96711 ? 37  PHE A CD2 1 
ATOM   284  C CE1 . PHE A 1 37  ? 19.52132  21.64466  -14.59330 1.000 41.77364 ? 37  PHE A CE1 1 
ATOM   285  C CE2 . PHE A 1 37  ? 21.29945  21.17800  -13.06553 1.000 37.23016 ? 37  PHE A CE2 1 
ATOM   286  C CZ  . PHE A 1 37  ? 20.87735  21.57361  -14.31510 1.000 43.73734 ? 37  PHE A CZ  1 
ATOM   287  N N   . LEU A 1 38  ? 15.76041  19.67499  -13.72212 1.000 29.03297 ? 38  LEU A N   1 
ATOM   288  C CA  . LEU A 1 38  ? 14.63402  20.09702  -14.54589 1.000 27.09434 ? 38  LEU A CA  1 
ATOM   289  C C   . LEU A 1 38  ? 13.46033  19.13377  -14.48295 1.000 26.97679 ? 38  LEU A C   1 
ATOM   290  O O   . LEU A 1 38  ? 12.51127  19.29785  -15.25697 1.000 24.66664 ? 38  LEU A O   1 
ATOM   291  C CB  . LEU A 1 38  ? 15.06538  20.27909  -16.00967 1.000 34.60747 ? 38  LEU A CB  1 
ATOM   292  C CG  . LEU A 1 38  ? 15.88373  21.51838  -16.38693 1.000 31.33730 ? 38  LEU A CG  1 
ATOM   293  C CD1 . LEU A 1 38  ? 16.47112  21.32423  -17.74634 1.000 25.25437 ? 38  LEU A CD1 1 
ATOM   294  C CD2 . LEU A 1 38  ? 15.06010  22.81698  -16.34985 1.000 24.40488 ? 38  LEU A CD2 1 
ATOM   295  N N   . ALA A 1 39  ? 13.48930  18.14381  -13.58821 1.000 28.41316 ? 39  ALA A N   1 
ATOM   296  C CA  . ALA A 1 39  ? 12.45709  17.11269  -13.52183 1.000 25.68401 ? 39  ALA A CA  1 
ATOM   297  C C   . ALA A 1 39  ? 11.65969  17.26688  -12.23142 1.000 27.58679 ? 39  ALA A C   1 
ATOM   298  O O   . ALA A 1 39  ? 12.17278  16.99871  -11.13727 1.000 23.97724 ? 39  ALA A O   1 
ATOM   299  C CB  . ALA A 1 39  ? 13.07142  15.72505  -13.63104 1.000 25.12384 ? 39  ALA A CB  1 
ATOM   300  N N   . GLN A 1 40  ? 10.40683  17.69838  -12.37583 1.000 26.02285 ? 40  GLN A N   1 
ATOM   301  C CA  . GLN A 1 40  ? 9.48535   17.90498  -11.27270 1.000 24.63037 ? 40  GLN A CA  1 
ATOM   302  C C   . GLN A 1 40  ? 8.54556   16.71412  -11.15278 1.000 31.96098 ? 40  GLN A C   1 
ATOM   303  O O   . GLN A 1 40  ? 8.07366   16.18250  -12.16260 1.000 32.01783 ? 40  GLN A O   1 
ATOM   304  C CB  . GLN A 1 40  ? 8.65867   19.18348  -11.45884 1.000 23.52991 ? 40  GLN A CB  1 
ATOM   305  C CG  . GLN A 1 40  ? 7.44947   19.27618  -10.50850 1.000 26.43984 ? 40  GLN A CG  1 
ATOM   306  C CD  . GLN A 1 40  ? 6.88481   20.67920  -10.36188 1.000 27.24865 ? 40  GLN A CD  1 
ATOM   307  O OE1 . GLN A 1 40  ? 5.88398   20.89752  -9.66852  1.000 22.91219 ? 40  GLN A OE1 1 
ATOM   308  N NE2 . GLN A 1 40  ? 7.52434   21.64041  -11.01674 1.000 34.20466 ? 40  GLN A NE2 1 
ATOM   309  N N   . VAL A 1 41  ? 8.27660   16.30588  -9.91072  1.000 27.09591 ? 41  VAL A N   1 
ATOM   310  C CA  . VAL A 1 41  ? 7.30733   15.26652  -9.58882  1.000 26.30103 ? 41  VAL A CA  1 
ATOM   311  C C   . VAL A 1 41  ? 6.29620   15.89017  -8.64552  1.000 32.50375 ? 41  VAL A C   1 
ATOM   312  O O   . VAL A 1 41  ? 6.59964   16.16240  -7.47413  1.000 37.04869 ? 41  VAL A O   1 
ATOM   313  C CB  . VAL A 1 41  ? 7.95583   14.02779  -8.96227  1.000 26.30909 ? 41  VAL A CB  1 
ATOM   314  C CG1 . VAL A 1 41  ? 6.87519   13.08651  -8.38146  1.000 25.77470 ? 41  VAL A CG1 1 
ATOM   315  C CG2 . VAL A 1 41  ? 8.79153   13.29642  -9.99644  1.000 26.74015 ? 41  VAL A CG2 1 
ATOM   316  N N   . ASN A 1 42  ? 5.10264   16.12808  -9.14257  1.000 29.99093 ? 42  ASN A N   1 
ATOM   317  C CA  . ASN A 1 42  ? 4.10276   16.87492  -8.40006  1.000 25.55030 ? 42  ASN A CA  1 
ATOM   318  C C   . ASN A 1 42  ? 3.03680   15.87764  -7.95766  1.000 26.02681 ? 42  ASN A C   1 
ATOM   319  O O   . ASN A 1 42  ? 2.26763   15.37667  -8.78396  1.000 23.91756 ? 42  ASN A O   1 
ATOM   320  C CB  . ASN A 1 42  ? 3.55686   17.99709  -9.27256  1.000 22.84460 ? 42  ASN A CB  1 
ATOM   321  C CG  . ASN A 1 42  ? 2.66999   18.94214  -8.52698  1.000 22.04117 ? 42  ASN A CG  1 
ATOM   322  O OD1 . ASN A 1 42  ? 1.49796   18.66473  -8.32921  1.000 25.44467 ? 42  ASN A OD1 1 
ATOM   323  N ND2 . ASN A 1 42  ? 3.20342   20.09524  -8.16016  1.000 21.82109 ? 42  ASN A ND2 1 
ATOM   324  N N   . PHE A 1 43  ? 3.03529   15.55884  -6.66102  1.000 22.33308 ? 43  PHE A N   1 
ATOM   325  C CA  . PHE A 1 43  ? 2.15866   14.53721  -6.09979  1.000 25.71143 ? 43  PHE A CA  1 
ATOM   326  C C   . PHE A 1 43  ? 0.80168   15.14627  -5.78677  1.000 24.84521 ? 43  PHE A C   1 
ATOM   327  O O   . PHE A 1 43  ? 0.71971   16.17331  -5.10339  1.000 25.20375 ? 43  PHE A O   1 
ATOM   328  C CB  . PHE A 1 43  ? 2.75640   13.92240  -4.81953  1.000 27.70412 ? 43  PHE A CB  1 
ATOM   329  C CG  . PHE A 1 43  ? 3.79474   12.84989  -5.06796  1.000 20.12988 ? 43  PHE A CG  1 
ATOM   330  C CD1 . PHE A 1 43  ? 3.45393   11.64976  -5.68057  1.000 23.39823 ? 43  PHE A CD1 1 
ATOM   331  C CD2 . PHE A 1 43  ? 5.10610   13.04183  -4.67294  1.000 20.46830 ? 43  PHE A CD2 1 
ATOM   332  C CE1 . PHE A 1 43  ? 4.41751   10.66925  -5.92368  1.000 25.78750 ? 43  PHE A CE1 1 
ATOM   333  C CE2 . PHE A 1 43  ? 6.07405   12.07681  -4.89579  1.000 25.22289 ? 43  PHE A CE2 1 
ATOM   334  C CZ  . PHE A 1 43  ? 5.73787   10.88156  -5.52549  1.000 27.19617 ? 43  PHE A CZ  1 
ATOM   335  N N   . GLN A 1 44  ? -0.25931  14.50052  -6.27065  1.000 20.68580 ? 44  GLN A N   1 
ATOM   336  C CA  . GLN A 1 44  ? -1.63462  14.99099  -6.14584  1.000 25.06837 ? 44  GLN A CA  1 
ATOM   337  C C   . GLN A 1 44  ? -2.47059  13.92815  -5.43758  1.000 29.86025 ? 44  GLN A C   1 
ATOM   338  O O   . GLN A 1 44  ? -2.88771  12.94084  -6.05689  1.000 32.53628 ? 44  GLN A O   1 
ATOM   339  C CB  . GLN A 1 44  ? -2.20658  15.33643  -7.51572  1.000 24.52983 ? 44  GLN A CB  1 
ATOM   340  C CG  . GLN A 1 44  ? -1.51989  16.51817  -8.16318  1.000 19.62087 ? 44  GLN A CG  1 
ATOM   341  C CD  . GLN A 1 44  ? -1.84197  17.81950  -7.46054  1.000 22.05205 ? 44  GLN A CD  1 
ATOM   342  O OE1 . GLN A 1 44  ? -2.94566  18.00880  -6.96641  1.000 24.85450 ? 44  GLN A OE1 1 
ATOM   343  N NE2 . GLN A 1 44  ? -0.87381  18.71139  -7.39233  1.000 21.14039 ? 44  GLN A NE2 1 
ATOM   344  N N   . GLU A 1 45  ? -2.70879  14.14306  -4.14242  1.000 27.29257 ? 45  GLU A N   1 
ATOM   345  C CA  . GLU A 1 45  ? -3.32853  13.17500  -3.24738  1.000 26.86526 ? 45  GLU A CA  1 
ATOM   346  C C   . GLU A 1 45  ? -4.80085  13.50111  -3.04813  1.000 35.54560 ? 45  GLU A C   1 
ATOM   347  O O   . GLU A 1 45  ? -5.16238  14.66345  -2.82869  1.000 36.82504 ? 45  GLU A O   1 
ATOM   348  C CB  . GLU A 1 45  ? -2.62659  13.17958  -1.88642  1.000 28.90878 ? 45  GLU A CB  1 
ATOM   349  C CG  . GLU A 1 45  ? -1.68572  12.01905  -1.61197  1.000 34.53494 ? 45  GLU A CG  1 
ATOM   350  C CD  . GLU A 1 45  ? -0.82134  12.27652  -0.39606  1.000 34.42680 ? 45  GLU A CD  1 
ATOM   351  O OE1 . GLU A 1 45  ? -0.44869  13.44615  -0.19952  1.000 41.13626 ? 45  GLU A OE1 1 
ATOM   352  O OE2 . GLU A 1 45  ? -0.52006  11.33253  0.36239   1.000 30.13657 ? 45  GLU A OE2 1 
ATOM   353  N N   . GLN A 1 46  ? -5.63818  12.46778  -3.08754  1.000 33.59824 ? 46  GLN A N   1 
ATOM   354  C CA  . GLN A 1 46  ? -7.07635  12.55393  -2.89312  1.000 27.24633 ? 46  GLN A CA  1 
ATOM   355  C C   . GLN A 1 46  ? -7.54453  11.48465  -1.91361  1.000 31.97630 ? 46  GLN A C   1 
ATOM   356  O O   . GLN A 1 46  ? -6.86390  10.47241  -1.71820  1.000 21.48046 ? 46  GLN A O   1 
ATOM   357  C CB  . GLN A 1 46  ? -7.80062  12.38208  -4.23318  1.000 25.77230 ? 46  GLN A CB  1 
ATOM   358  C CG  . GLN A 1 46  ? -7.52326  13.49466  -5.21810  1.000 30.14691 ? 46  GLN A CG  1 
ATOM   359  C CD  . GLN A 1 46  ? -8.25357  14.77051  -4.86847  1.000 29.74165 ? 46  GLN A CD  1 
ATOM   360  O OE1 . GLN A 1 46  ? -9.49009  14.78439  -4.74994  1.000 26.81275 ? 46  GLN A OE1 1 
ATOM   361  N NE2 . GLN A 1 46  ? -7.49509  15.85587  -4.68946  1.000 28.57670 ? 46  GLN A NE2 1 
ATOM   362  N N   . PRO A 1 47  ? -8.70460  11.67310  -1.27588  1.000 29.68697 ? 47  PRO A N   1 
ATOM   363  C CA  . PRO A 1 47  ? -9.26011  10.58831  -0.46264  1.000 29.28419 ? 47  PRO A CA  1 
ATOM   364  C C   . PRO A 1 47  ? -9.54435  9.37103   -1.32610  1.000 27.48557 ? 47  PRO A C   1 
ATOM   365  O O   . PRO A 1 47  ? -9.83498  9.48536   -2.51695  1.000 32.35312 ? 47  PRO A O   1 
ATOM   366  C CB  . PRO A 1 47  ? -10.55082 11.18340  0.10845   1.000 29.94875 ? 47  PRO A CB  1 
ATOM   367  C CG  . PRO A 1 47  ? -10.87829 12.35395  -0.79001  1.000 26.60499 ? 47  PRO A CG  1 
ATOM   368  C CD  . PRO A 1 47  ? -9.55691  12.87753  -1.25143  1.000 25.47868 ? 47  PRO A CD  1 
ATOM   369  N N   . ALA A 1 48  ? -9.43629  8.19638   -0.70827  1.000 31.36257 ? 48  ALA A N   1 
ATOM   370  C CA  . ALA A 1 48  ? -9.76092  6.93852   -1.37294  1.000 30.24902 ? 48  ALA A CA  1 
ATOM   371  C C   . ALA A 1 48  ? -11.25822 6.84814   -1.63735  1.000 24.45458 ? 48  ALA A C   1 
ATOM   372  O O   . ALA A 1 48  ? -12.06943 7.07093   -0.73851  1.000 29.03288 ? 48  ALA A O   1 
ATOM   373  C CB  . ALA A 1 48  ? -9.31557  5.75883   -0.50807  1.000 34.97804 ? 48  ALA A CB  1 
ATOM   374  N N   . GLY A 1 49  ? -11.63138 6.51002   -2.86140  1.000 26.75607 ? 49  GLY A N   1 
ATOM   375  C CA  . GLY A 1 49  ? -13.02769 6.52206   -3.25863  1.000 27.56480 ? 49  GLY A CA  1 
ATOM   376  C C   . GLY A 1 49  ? -13.38196 7.55449   -4.30465  1.000 23.36752 ? 49  GLY A C   1 
ATOM   377  O O   . GLY A 1 49  ? -14.54250 7.60779   -4.74305  1.000 16.34121 ? 49  GLY A O   1 
ATOM   378  N N   . ASN A 1 50  ? -12.43126 8.39285   -4.70318  1.000 26.14309 ? 50  ASN A N   1 
ATOM   379  C CA  . ASN A 1 50  ? -12.61234 9.26667   -5.84956  1.000 20.58196 ? 50  ASN A CA  1 
ATOM   380  C C   . ASN A 1 50  ? -12.15804 8.62517   -7.14893  1.000 23.72272 ? 50  ASN A C   1 
ATOM   381  O O   . ASN A 1 50  ? -12.51664 9.11986   -8.22226  1.000 27.01666 ? 50  ASN A O   1 
ATOM   382  C CB  . ASN A 1 50  ? -11.83566 10.56802  -5.66779  1.000 22.39024 ? 50  ASN A CB  1 
ATOM   383  C CG  . ASN A 1 50  ? -12.11697 11.22706  -4.36733  1.000 25.07467 ? 50  ASN A CG  1 
ATOM   384  O OD1 . ASN A 1 50  ? -13.10543 10.93071  -3.71300  1.000 21.78191 ? 50  ASN A OD1 1 
ATOM   385  N ND2 . ASN A 1 50  ? -11.24325 12.14639  -3.97692  1.000 32.80152 ? 50  ASN A ND2 1 
ATOM   386  N N   . VAL A 1 51  ? -11.34844 7.57091   -7.08567  1.000 23.09179 ? 51  VAL A N   1 
ATOM   387  C CA  . VAL A 1 51  ? -10.89414 6.87969   -8.28932  1.000 26.56902 ? 51  VAL A CA  1 
ATOM   388  C C   . VAL A 1 51  ? -11.91239 5.80473   -8.64989  1.000 28.35440 ? 51  VAL A C   1 
ATOM   389  O O   . VAL A 1 51  ? -12.22169 4.92660   -7.83190  1.000 22.48225 ? 51  VAL A O   1 
ATOM   390  C CB  . VAL A 1 51  ? -9.49661  6.27104   -8.10023  1.000 24.22086 ? 51  VAL A CB  1 
ATOM   391  C CG1 . VAL A 1 51  ? -9.02155  5.63686   -9.40781  1.000 20.65857 ? 51  VAL A CG1 1 
ATOM   392  C CG2 . VAL A 1 51  ? -8.51099  7.32318   -7.61134  1.000 28.79792 ? 51  VAL A CG2 1 
ATOM   393  N N   . PHE A 1 52  ? -12.42701 5.87498   -9.87708  1.000 24.50592 ? 52  PHE A N   1 
ATOM   394  C CA  . PHE A 1 52  ? -13.35645 4.88690   -10.40747 1.000 25.96874 ? 52  PHE A CA  1 
ATOM   395  C C   . PHE A 1 52  ? -12.75157 4.23445   -11.64478 1.000 23.85071 ? 52  PHE A C   1 
ATOM   396  O O   . PHE A 1 52  ? -12.24023 4.92183   -12.53447 1.000 20.14098 ? 52  PHE A O   1 
ATOM   397  C CB  . PHE A 1 52  ? -14.71477 5.52087   -10.74296 1.000 23.33345 ? 52  PHE A CB  1 
ATOM   398  C CG  . PHE A 1 52  ? -15.52446 5.92336   -9.52798  1.000 28.76533 ? 52  PHE A CG  1 
ATOM   399  C CD1 . PHE A 1 52  ? -15.36261 7.17323   -8.94395  1.000 21.64550 ? 52  PHE A CD1 1 
ATOM   400  C CD2 . PHE A 1 52  ? -16.44982 5.04735   -8.97072  1.000 29.19519 ? 52  PHE A CD2 1 
ATOM   401  C CE1 . PHE A 1 52  ? -16.09827 7.53715   -7.84108  1.000 23.76008 ? 52  PHE A CE1 1 
ATOM   402  C CE2 . PHE A 1 52  ? -17.19112 5.41006   -7.85973  1.000 27.53876 ? 52  PHE A CE2 1 
ATOM   403  C CZ  . PHE A 1 52  ? -17.01601 6.65200   -7.29207  1.000 31.10743 ? 52  PHE A CZ  1 
ATOM   404  N N   . LEU A 1 53  ? -12.79976 2.90747   -11.69171 1.000 27.32961 ? 53  LEU A N   1 
ATOM   405  C CA  . LEU A 1 53  ? -12.41376 2.13951   -12.86452 1.000 19.61187 ? 53  LEU A CA  1 
ATOM   406  C C   . LEU A 1 53  ? -13.63386 1.37529   -13.33889 1.000 25.93444 ? 53  LEU A C   1 
ATOM   407  O O   . LEU A 1 53  ? -14.24956 0.63925   -12.55808 1.000 24.10045 ? 53  LEU A O   1 
ATOM   408  C CB  . LEU A 1 53  ? -11.27306 1.17566   -12.55620 1.000 18.50556 ? 53  LEU A CB  1 
ATOM   409  C CG  . LEU A 1 53  ? -9.99297  1.82960   -12.04916 1.000 21.89443 ? 53  LEU A CG  1 
ATOM   410  C CD1 . LEU A 1 53  ? -8.87388  0.80349   -11.83972 1.000 17.22856 ? 53  LEU A CD1 1 
ATOM   411  C CD2 . LEU A 1 53  ? -9.58095  2.92433   -13.00422 1.000 17.44551 ? 53  LEU A CD2 1 
ATOM   412  N N   . GLY A 1 54  ? -13.97319 1.54937   -14.61639 1.000 24.93577 ? 54  GLY A N   1 
ATOM   413  C CA  . GLY A 1 54  ? -15.14624 0.93289   -15.19756 1.000 27.58412 ? 54  GLY A CA  1 
ATOM   414  C C   . GLY A 1 54  ? -16.42311 1.24386   -14.43998 1.000 30.11540 ? 54  GLY A C   1 
ATOM   415  O O   . GLY A 1 54  ? -17.37233 0.45613   -14.47621 1.000 31.88203 ? 54  GLY A O   1 
ATOM   416  N N   . GLY A 1 55  ? -16.46150 2.38851   -13.75453 1.000 25.66584 ? 55  GLY A N   1 
ATOM   417  C CA  . GLY A 1 55  ? -17.61723 2.76233   -12.95955 1.000 28.53803 ? 55  GLY A CA  1 
ATOM   418  C C   . GLY A 1 55  ? -17.65570 2.20162   -11.55266 1.000 25.06447 ? 55  GLY A C   1 
ATOM   419  O O   . GLY A 1 55  ? -18.66500 2.37948   -10.86650 1.000 38.91332 ? 55  GLY A O   1 
ATOM   420  N N   . VAL A 1 56  ? -16.59401 1.53827   -11.10171 1.000 21.82736 ? 56  VAL A N   1 
ATOM   421  C CA  . VAL A 1 56  ? -16.51279 0.93245   -9.77371  1.000 30.48885 ? 56  VAL A CA  1 
ATOM   422  C C   . VAL A 1 56  ? -15.50023 1.71146   -8.93864  1.000 28.31609 ? 56  VAL A C   1 
ATOM   423  O O   . VAL A 1 56  ? -14.37289 1.95811   -9.38654  1.000 25.75025 ? 56  VAL A O   1 
ATOM   424  C CB  . VAL A 1 56  ? -16.12022 -0.55626  -9.85462  1.000 27.25417 ? 56  VAL A CB  1 
ATOM   425  C CG1 . VAL A 1 56  ? -15.37354 -0.97992  -8.60585  1.000 31.31257 ? 56  VAL A CG1 1 
ATOM   426  C CG2 . VAL A 1 56  ? -17.34073 -1.41978  -10.03947 1.000 27.87222 ? 56  VAL A CG2 1 
ATOM   427  N N   . GLN A 1 57  ? -15.89713 2.09218   -7.72314  1.000 25.39240 ? 57  GLN A N   1 
ATOM   428  C CA  . GLN A 1 57  ? -14.98736 2.79847   -6.82653  1.000 25.38275 ? 57  GLN A CA  1 
ATOM   429  C C   . GLN A 1 57  ? -13.83781 1.88500   -6.40929  1.000 28.08658 ? 57  GLN A C   1 
ATOM   430  O O   . GLN A 1 57  ? -14.06175 0.73979   -6.00723  1.000 31.45694 ? 57  GLN A O   1 
ATOM   431  C CB  . GLN A 1 57  ? -15.74576 3.30110   -5.60049  1.000 27.38846 ? 57  GLN A CB  1 
ATOM   432  C CG  . GLN A 1 57  ? -14.88860 4.03576   -4.60159  1.000 24.03703 ? 57  GLN A CG  1 
ATOM   433  C CD  . GLN A 1 57  ? -15.66278 4.46893   -3.36917  1.000 30.38502 ? 57  GLN A CD  1 
ATOM   434  O OE1 . GLN A 1 57  ? -16.81661 4.86847   -3.46917  1.000 32.97822 ? 57  GLN A OE1 1 
ATOM   435  N NE2 . GLN A 1 57  ? -15.02939 4.38753   -2.19825  1.000 21.69951 ? 57  GLN A NE2 1 
ATOM   436  N N   . GLN A 1 58  ? -12.60889 2.38711   -6.52479  1.000 26.78198 ? 58  GLN A N   1 
ATOM   437  C CA  . GLN A 1 58  ? -11.39562 1.64369   -6.20515  1.000 24.77846 ? 58  GLN A CA  1 
ATOM   438  C C   . GLN A 1 58  ? -10.97325 1.86596   -4.74740  1.000 25.76475 ? 58  GLN A C   1 
ATOM   439  O O   . GLN A 1 58  ? -11.44899 2.76809   -4.05866  1.000 18.11403 ? 58  GLN A O   1 
ATOM   440  C CB  . GLN A 1 58  ? -10.25961 2.06378   -7.14005  1.000 19.08844 ? 58  GLN A CB  1 
ATOM   441  C CG  . GLN A 1 58  ? -9.86895  1.05667   -8.21746  1.000 23.52079 ? 58  GLN A CG  1 
ATOM   442  C CD  . GLN A 1 58  ? -11.04632 0.27482   -8.75402  1.000 26.32036 ? 58  GLN A CD  1 
ATOM   443  O OE1 . GLN A 1 58  ? -12.01919 0.84493   -9.24476  1.000 28.12013 ? 58  GLN A OE1 1 
ATOM   444  N NE2 . GLN A 1 58  ? -10.97011 -1.04742  -8.64440  1.000 29.89947 ? 58  GLN A NE2 1 
ATOM   445  N N   . GLY A 1 59  ? -10.05238 1.02698   -4.27953  1.000 31.07849 ? 59  GLY A N   1 
ATOM   446  C CA  . GLY A 1 59  ? -9.41224  1.30540   -3.01131  1.000 25.35582 ? 59  GLY A CA  1 
ATOM   447  C C   . GLY A 1 59  ? -8.52653  2.53132   -3.13344  1.000 29.58426 ? 59  GLY A C   1 
ATOM   448  O O   . GLY A 1 59  ? -8.92914  3.53857   -3.72562  1.000 30.04585 ? 59  GLY A O   1 
ATOM   449  N N   . GLY A 1 60  ? -7.31668  2.46282   -2.59101  1.000 26.99864 ? 60  GLY A N   1 
ATOM   450  C CA  . GLY A 1 60  ? -6.37768  3.55914   -2.72182  1.000 24.41350 ? 60  GLY A CA  1 
ATOM   451  C C   . GLY A 1 60  ? -5.12385  3.13173   -3.45512  1.000 28.17131 ? 60  GLY A C   1 
ATOM   452  O O   . GLY A 1 60  ? -4.03238  3.65606   -3.22191  1.000 21.65476 ? 60  GLY A O   1 
ATOM   453  N N   . ASP A 1 61  ? -5.28596  2.16643   -4.35867  1.000 35.39432 ? 61  ASP A N   1 
ATOM   454  C CA  . ASP A 1 61  ? -4.17569  1.44602   -4.95775  1.000 27.23451 ? 61  ASP A CA  1 
ATOM   455  C C   . ASP A 1 61  ? -3.90932  1.84578   -6.39928  1.000 29.84094 ? 61  ASP A C   1 
ATOM   456  O O   . ASP A 1 61  ? -3.14131  1.16621   -7.08637  1.000 41.64214 ? 61  ASP A O   1 
ATOM   457  C CB  . ASP A 1 61  ? -4.43973  -0.05334  -4.85664  1.000 30.89490 ? 61  ASP A CB  1 
ATOM   458  C CG  . ASP A 1 61  ? -4.58985  -0.50561  -3.42295  1.000 39.35626 ? 61  ASP A CG  1 
ATOM   459  O OD1 . ASP A 1 61  ? -3.62051  -0.33234  -2.64686  1.000 43.74984 ? 61  ASP A OD1 1 
ATOM   460  O OD2 . ASP A 1 61  ? -5.68137  -0.99983  -3.05960  1.000 42.60556 ? 61  ASP A OD2 1 
ATOM   461  N N   . THR A 1 62  ? -4.51287  2.92115   -6.88244  1.000 25.26373 ? 62  THR A N   1 
ATOM   462  C CA  . THR A 1 62  ? -4.31014  3.34607   -8.25636  1.000 22.73239 ? 62  THR A CA  1 
ATOM   463  C C   . THR A 1 62  ? -3.29640  4.47717   -8.29074  1.000 26.20453 ? 62  THR A C   1 
ATOM   464  O O   . THR A 1 62  ? -3.38124  5.42602   -7.50266  1.000 30.54556 ? 62  THR A O   1 
ATOM   465  C CB  . THR A 1 62  ? -5.61895  3.78492   -8.90415  1.000 24.14158 ? 62  THR A CB  1 
ATOM   466  O OG1 . THR A 1 62  ? -6.27063  2.63254   -9.44849  1.000 26.51381 ? 62  THR A OG1 1 
ATOM   467  C CG2 . THR A 1 62  ? -5.36139  4.81197   -10.01505 1.000 27.62664 ? 62  THR A CG2 1 
ATOM   468  N N   . ILE A 1 63  ? -2.32022  4.34814   -9.17316  1.000 17.04728 ? 63  ILE A N   1 
ATOM   469  C CA  . ILE A 1 63  ? -1.41586  5.42904   -9.51232  1.000 16.75944 ? 63  ILE A CA  1 
ATOM   470  C C   . ILE A 1 63  ? -1.74308  5.86577   -10.92903 1.000 17.79691 ? 63  ILE A C   1 
ATOM   471  O O   . ILE A 1 63  ? -2.06931  5.03553   -11.78388 1.000 17.53333 ? 63  ILE A O   1 
ATOM   472  C CB  . ILE A 1 63  ? 0.05810   5.00532   -9.39544  1.000 18.47893 ? 63  ILE A CB  1 
ATOM   473  C CG1 . ILE A 1 63  ? 0.23775   4.10156   -8.16381  1.000 19.47823 ? 63  ILE A CG1 1 
ATOM   474  C CG2 . ILE A 1 63  ? 0.94942   6.24138   -9.35770  1.000 14.02123 ? 63  ILE A CG2 1 
ATOM   475  C CD1 . ILE A 1 63  ? 1.68024   3.89859   -7.70585  1.000 21.20576 ? 63  ILE A CD1 1 
ATOM   476  N N   . PHE A 1 64  ? -1.69119  7.17054   -11.16581 1.000 16.24152 ? 64  PHE A N   1 
ATOM   477  C CA  . PHE A 1 64  ? -1.76982  7.70573   -12.51283 1.000 19.05433 ? 64  PHE A CA  1 
ATOM   478  C C   . PHE A 1 64  ? -0.62467  8.69256   -12.69793 1.000 18.19339 ? 64  PHE A C   1 
ATOM   479  O O   . PHE A 1 64  ? -0.56052  9.71439   -12.00581 1.000 18.14350 ? 64  PHE A O   1 
ATOM   480  C CB  . PHE A 1 64  ? -3.14280  8.33819   -12.76862 1.000 17.86632 ? 64  PHE A CB  1 
ATOM   481  C CG  . PHE A 1 64  ? -3.24779  9.05857   -14.07304 1.000 13.53548 ? 64  PHE A CG  1 
ATOM   482  C CD1 . PHE A 1 64  ? -2.78431  8.47251   -15.25070 1.000 15.60780 ? 64  PHE A CD1 1 
ATOM   483  C CD2 . PHE A 1 64  ? -3.84510  10.31324  -14.13598 1.000 14.27133 ? 64  PHE A CD2 1 
ATOM   484  C CE1 . PHE A 1 64  ? -2.87172  9.13810   -16.46168 1.000 11.99420 ? 64  PHE A CE1 1 
ATOM   485  C CE2 . PHE A 1 64  ? -3.95343  10.99571  -15.37332 1.000 13.58661 ? 64  PHE A CE2 1 
ATOM   486  C CZ  . PHE A 1 64  ? -3.45386  10.40457  -16.52165 1.000 12.81573 ? 64  PHE A CZ  1 
ATOM   487  N N   . VAL A 1 65  ? 0.29838   8.35081   -13.59645 1.000 18.04562 ? 65  VAL A N   1 
ATOM   488  C CA  . VAL A 1 65  ? 1.45570   9.16770   -13.94504 1.000 16.91010 ? 65  VAL A CA  1 
ATOM   489  C C   . VAL A 1 65  ? 1.16907   9.83361   -15.28233 1.000 15.35881 ? 65  VAL A C   1 
ATOM   490  O O   . VAL A 1 65  ? 1.02740   9.15374   -16.30306 1.000 18.50879 ? 65  VAL A O   1 
ATOM   491  C CB  . VAL A 1 65  ? 2.74868   8.34120   -14.03657 1.000 19.39476 ? 65  VAL A CB  1 
ATOM   492  C CG1 . VAL A 1 65  ? 3.95580   9.27288   -14.33315 1.000 19.79065 ? 65  VAL A CG1 1 
ATOM   493  C CG2 . VAL A 1 65  ? 2.99324   7.51876   -12.77923 1.000 13.95427 ? 65  VAL A CG2 1 
ATOM   494  N N   . HIS A 1 66  ? 1.11111   11.15958  -15.27555 1.000 18.01655 ? 66  HIS A N   1 
ATOM   495  C CA  . HIS A 1 66  ? 0.81564   11.98616  -16.44216 1.000 12.53101 ? 66  HIS A CA  1 
ATOM   496  C C   . HIS A 1 66  ? 2.05429   12.84467  -16.66895 1.000 13.44278 ? 66  HIS A C   1 
ATOM   497  O O   . HIS A 1 66  ? 2.35470   13.72023  -15.85205 1.000 20.36059 ? 66  HIS A O   1 
ATOM   498  C CB  . HIS A 1 66  ? -0.43612  12.82764  -16.18301 1.000 12.74549 ? 66  HIS A CB  1 
ATOM   499  C CG  . HIS A 1 66  ? -0.89283  13.66059  -17.34124 1.000 20.00529 ? 66  HIS A CG  1 
ATOM   500  N ND1 . HIS A 1 66  ? -1.65724  14.79320  -17.16996 1.000 14.80011 ? 66  HIS A ND1 1 
ATOM   501  C CD2 . HIS A 1 66  ? -0.73211  13.51589  -18.68029 1.000 18.55401 ? 66  HIS A CD2 1 
ATOM   502  C CE1 . HIS A 1 66  ? -1.93651  15.31849  -18.34875 1.000 13.56738 ? 66  HIS A CE1 1 
ATOM   503  N NE2 . HIS A 1 66  ? -1.37991  14.56928  -19.28044 1.000 15.96151 ? 66  HIS A NE2 1 
ATOM   504  N N   . GLY A 1 67  ? 2.79257   12.56987  -17.73274 1.000 19.94020 ? 67  GLY A N   1 
ATOM   505  C CA  . GLY A 1 67  ? 4.03417   13.27147  -18.01403 1.000 21.16844 ? 67  GLY A CA  1 
ATOM   506  C C   . GLY A 1 67  ? 3.84705   14.33495  -19.07686 1.000 17.41886 ? 67  GLY A C   1 
ATOM   507  O O   . GLY A 1 67  ? 3.32576   14.06439  -20.15823 1.000 20.56456 ? 67  GLY A O   1 
ATOM   508  N N   . LEU A 1 68  ? 4.28893   15.54115  -18.75720 1.000 17.71839 ? 68  LEU A N   1 
ATOM   509  C CA  . LEU A 1 68  ? 4.25651   16.69116  -19.65034 1.000 16.71900 ? 68  LEU A CA  1 
ATOM   510  C C   . LEU A 1 68  ? 5.68266   16.98361  -20.13236 1.000 19.21682 ? 68  LEU A C   1 
ATOM   511  O O   . LEU A 1 68  ? 6.54108   17.38109  -19.33672 1.000 18.83191 ? 68  LEU A O   1 
ATOM   512  C CB  . LEU A 1 68  ? 3.64657   17.88523  -18.92138 1.000 12.59609 ? 68  LEU A CB  1 
ATOM   513  C CG  . LEU A 1 68  ? 2.25074   17.63898  -18.32381 1.000 14.07895 ? 68  LEU A CG  1 
ATOM   514  C CD1 . LEU A 1 68  ? 1.62729   18.93790  -17.86220 1.000 11.83668 ? 68  LEU A CD1 1 
ATOM   515  C CD2 . LEU A 1 68  ? 1.30847   16.91581  -19.30774 1.000 11.66440 ? 68  LEU A CD2 1 
ATOM   516  N N   . HIS A 1 69  ? 5.92809   16.79453  -21.43232 1.000 16.55313 ? 69  HIS A N   1 
ATOM   517  C CA  . HIS A 1 69  ? 7.26713   16.77280  -22.01529 1.000 16.04564 ? 69  HIS A CA  1 
ATOM   518  C C   . HIS A 1 69  ? 7.42170   17.81166  -23.12836 1.000 20.92001 ? 69  HIS A C   1 
ATOM   519  O O   . HIS A 1 69  ? 6.45462   18.39649  -23.62451 1.000 18.09328 ? 69  HIS A O   1 
ATOM   520  C CB  . HIS A 1 69  ? 7.59947   15.38489  -22.59548 1.000 18.64485 ? 69  HIS A CB  1 
ATOM   521  C CG  . HIS A 1 69  ? 7.55719   14.28076  -21.58839 1.000 19.89391 ? 69  HIS A CG  1 
ATOM   522  N ND1 . HIS A 1 69  ? 6.82927   13.12296  -21.77788 1.000 26.28108 ? 69  HIS A ND1 1 
ATOM   523  C CD2 . HIS A 1 69  ? 8.14817   14.15973  -20.37903 1.000 23.19766 ? 69  HIS A CD2 1 
ATOM   524  C CE1 . HIS A 1 69  ? 6.97257   12.34107  -20.72380 1.000 24.89485 ? 69  HIS A CE1 1 
ATOM   525  N NE2 . HIS A 1 69  ? 7.76406   12.94771  -19.85898 1.000 28.50964 ? 69  HIS A NE2 1 
ATOM   526  N N   . ARG A 1 70  ? 8.67904   18.03314  -23.50869 1.000 23.33416 ? 70  ARG A N   1 
ATOM   527  C CA  . ARG A 1 70  ? 9.01320   18.71163  -24.75632 1.000 18.34042 ? 70  ARG A CA  1 
ATOM   528  C C   . ARG A 1 70  ? 8.63090   17.82766  -25.93401 1.000 19.21819 ? 70  ARG A C   1 
ATOM   529  O O   . ARG A 1 70  ? 8.90173   16.63009  -25.92071 1.000 17.48460 ? 70  ARG A O   1 
ATOM   530  C CB  . ARG A 1 70  ? 10.52263  18.97387  -24.84232 1.000 19.01615 ? 70  ARG A CB  1 
ATOM   531  C CG  . ARG A 1 70  ? 11.03320  20.27557  -24.32798 1.000 24.56823 ? 70  ARG A CG  1 
ATOM   532  C CD  . ARG A 1 70  ? 11.98853  20.10357  -23.14852 1.000 30.22784 ? 70  ARG A CD  1 
ATOM   533  N NE  . ARG A 1 70  ? 13.37190  19.96988  -23.59828 1.000 31.64572 ? 70  ARG A NE  1 
ATOM   534  C CZ  . ARG A 1 70  ? 14.31914  19.31918  -22.94117 1.000 27.57762 ? 70  ARG A CZ  1 
ATOM   535  N NH1 . ARG A 1 70  ? 14.05918  18.66501  -21.82454 1.000 30.53830 ? 70  ARG A NH1 1 
ATOM   536  N NH2 . ARG A 1 70  ? 15.55522  19.31408  -23.42304 1.000 33.62327 ? 70  ARG A NH2 1 
ATOM   537  N N   . GLU A 1 71  ? 8.03317   18.41667  -26.96419 1.000 21.27390 ? 71  GLU A N   1 
ATOM   538  C CA  . GLU A 1 71  ? 8.01314   17.77109  -28.27047 1.000 19.52280 ? 71  GLU A CA  1 
ATOM   539  C C   . GLU A 1 71  ? 9.44381   17.57257  -28.75407 1.000 18.87862 ? 71  GLU A C   1 
ATOM   540  O O   . GLU A 1 71  ? 10.33019  18.38401  -28.46643 1.000 17.84368 ? 71  GLU A O   1 
ATOM   541  C CB  . GLU A 1 71  ? 7.23055   18.61815  -29.27925 1.000 17.28369 ? 71  GLU A CB  1 
ATOM   542  C CG  . GLU A 1 71  ? 5.74107   18.74770  -28.98797 1.000 20.54589 ? 71  GLU A CG  1 
ATOM   543  C CD  . GLU A 1 71  ? 5.07629   19.78302  -29.86772 1.000 20.78478 ? 71  GLU A CD  1 
ATOM   544  O OE1 . GLU A 1 71  ? 5.78080   20.43807  -30.65817 1.000 26.71902 ? 71  GLU A OE1 1 
ATOM   545  O OE2 . GLU A 1 71  ? 3.84681   19.94942  -29.77166 1.000 27.20317 ? 71  GLU A OE2 1 
ATOM   546  N N   . GLY A 1 72  ? 9.67621   16.48207  -29.48145 1.000 13.95664 ? 72  GLY A N   1 
ATOM   547  C CA  . GLY A 1 72  ? 11.01627  16.24433  -29.97097 1.000 16.01557 ? 72  GLY A CA  1 
ATOM   548  C C   . GLY A 1 72  ? 11.47656  14.79874  -30.00948 1.000 19.64287 ? 72  GLY A C   1 
ATOM   549  O O   . GLY A 1 72  ? 12.21310  14.41251  -30.92442 1.000 19.37250 ? 72  GLY A O   1 
ATOM   550  N N   . ARG A 1 73  ? 11.04986  13.97965  -29.05455 1.000 17.62720 ? 73  ARG A N   1 
ATOM   551  C CA  . ARG A 1 73  ? 11.64713  12.66063  -28.88593 1.000 15.96963 ? 73  ARG A CA  1 
ATOM   552  C C   . ARG A 1 73  ? 10.93696  11.58214  -29.72105 1.000 22.61088 ? 73  ARG A C   1 
ATOM   553  O O   . ARG A 1 73  ? 9.75346   11.69388  -30.05752 1.000 22.51539 ? 73  ARG A O   1 
ATOM   554  C CB  . ARG A 1 73  ? 11.67607  12.31895  -27.39421 1.000 17.71565 ? 73  ARG A CB  1 
ATOM   555  C CG  . ARG A 1 73  ? 12.51645  13.36511  -26.64596 1.000 17.04480 ? 73  ARG A CG  1 
ATOM   556  C CD  . ARG A 1 73  ? 12.98316  12.98806  -25.24856 1.000 24.74841 ? 73  ARG A CD  1 
ATOM   557  N NE  . ARG A 1 73  ? 13.58038  14.12706  -24.54389 1.000 19.18705 ? 73  ARG A NE  1 
ATOM   558  C CZ  . ARG A 1 73  ? 12.94800  14.85381  -23.62800 1.000 25.96916 ? 73  ARG A CZ  1 
ATOM   559  N NH1 . ARG A 1 73  ? 11.70717  14.57519  -23.26145 1.000 26.19315 ? 73  ARG A NH1 1 
ATOM   560  N NH2 . ARG A 1 73  ? 13.57420  15.88733  -23.06499 1.000 23.55521 ? 73  ARG A NH2 1 
ATOM   561  N N   . SER A 1 74  ? 11.68914  10.54431  -30.08973 1.000 21.32517 ? 74  SER A N   1 
ATOM   562  C CA  . SER A 1 74  ? 11.11399  9.45666   -30.87990 1.000 19.96196 ? 74  SER A CA  1 
ATOM   563  C C   . SER A 1 74  ? 10.01494  8.73816   -30.10168 1.000 15.56666 ? 74  SER A C   1 
ATOM   564  O O   . SER A 1 74  ? 10.09915  8.59157   -28.88881 1.000 14.97621 ? 74  SER A O   1 
ATOM   565  C CB  . SER A 1 74  ? 12.20710  8.46463   -31.29633 1.000 19.84996 ? 74  SER A CB  1 
ATOM   566  O OG  . SER A 1 74  ? 12.76568  7.78163   -30.18876 1.000 13.85197 ? 74  SER A OG  1 
ATOM   567  N N   . ALA A 1 75  ? 8.95985   8.31555   -30.80713 1.000 17.75648 ? 75  ALA A N   1 
ATOM   568  C CA  . ALA A 1 75  ? 7.97304   7.42292   -30.19865 1.000 20.47115 ? 75  ALA A CA  1 
ATOM   569  C C   . ALA A 1 75  ? 8.65166   6.26245   -29.46821 1.000 22.23865 ? 75  ALA A C   1 
ATOM   570  O O   . ALA A 1 75  ? 8.26870   5.90746   -28.34710 1.000 21.49256 ? 75  ALA A O   1 
ATOM   571  C CB  . ALA A 1 75  ? 7.00508   6.88856   -31.25535 1.000 10.09641 ? 75  ALA A CB  1 
ATOM   572  N N   . ASP A 1 76  ? 9.69900   5.69980   -30.06922 1.000 23.89763 ? 76  ASP A N   1 
ATOM   573  C CA  . ASP A 1 76  ? 10.37986  4.55193   -29.47524 1.000 27.35574 ? 76  ASP A CA  1 
ATOM   574  C C   . ASP A 1 76  ? 10.94451  4.89168   -28.09854 1.000 18.45347 ? 76  ASP A C   1 
ATOM   575  O O   . ASP A 1 76  ? 10.75811  4.13887   -27.13795 1.000 21.10779 ? 76  ASP A O   1 
ATOM   576  C CB  . ASP A 1 76  ? 11.48987  4.06781   -30.40566 1.000 21.71918 ? 76  ASP A CB  1 
ATOM   577  C CG  . ASP A 1 76  ? 11.00734  3.84135   -31.83813 1.000 41.62570 ? 76  ASP A CG  1 
ATOM   578  O OD1 . ASP A 1 76  ? 10.01402  4.47884   -32.27560 1.000 32.71800 ? 76  ASP A OD1 1 
ATOM   579  O OD2 . ASP A 1 76  ? 11.62817  3.00282   -32.53529 1.000 47.53236 ? 76  ASP A OD2 1 
ATOM   580  N N   . LEU A 1 77  ? 11.65574  6.01698   -27.99082 1.000 18.25300 ? 77  LEU A N   1 
ATOM   581  C CA  . LEU A 1 77  ? 12.21282  6.42500   -26.70372 1.000 18.03737 ? 77  LEU A CA  1 
ATOM   582  C C   . LEU A 1 77  ? 11.10528  6.64777   -25.68790 1.000 19.52787 ? 77  LEU A C   1 
ATOM   583  O O   . LEU A 1 77  ? 11.20890  6.21792   -24.53378 1.000 23.17863 ? 77  LEU A O   1 
ATOM   584  C CB  . LEU A 1 77  ? 13.06810  7.68601   -26.87005 1.000 21.01399 ? 77  LEU A CB  1 
ATOM   585  C CG  . LEU A 1 77  ? 13.58669  8.44658   -25.64390 1.000 21.83448 ? 77  LEU A CG  1 
ATOM   586  C CD1 . LEU A 1 77  ? 14.84762  9.20300   -25.99893 1.000 17.87482 ? 77  LEU A CD1 1 
ATOM   587  C CD2 . LEU A 1 77  ? 12.55889  9.41359   -25.08983 1.000 20.67532 ? 77  LEU A CD2 1 
ATOM   588  N N   . LYS A 1 78  ? 10.02435  7.31431   -26.11063 1.000 25.32605 ? 78  LYS A N   1 
ATOM   589  C CA  . LYS A 1 78  ? 8.92654   7.60694   -25.19906 1.000 16.88492 ? 78  LYS A CA  1 
ATOM   590  C C   . LYS A 1 78  ? 8.25118   6.33249   -24.72456 1.000 15.86019 ? 78  LYS A C   1 
ATOM   591  O O   . LYS A 1 78  ? 7.78343   6.26584   -23.58533 1.000 20.58454 ? 78  LYS A O   1 
ATOM   592  C CB  . LYS A 1 78  ? 7.92901   8.54285   -25.87276 1.000 15.01665 ? 78  LYS A CB  1 
ATOM   593  C CG  . LYS A 1 78  ? 8.47694   9.94531   -26.10660 1.000 18.79125 ? 78  LYS A CG  1 
ATOM   594  C CD  . LYS A 1 78  ? 7.43723   10.85797  -26.71141 1.000 17.22639 ? 78  LYS A CD  1 
ATOM   595  C CE  . LYS A 1 78  ? 7.23400   10.53634  -28.18544 1.000 16.92278 ? 78  LYS A CE  1 
ATOM   596  N NZ  . LYS A 1 78  ? 6.05462   11.25425  -28.73879 1.000 11.69606 ? 78  LYS A NZ  1 
ATOM   597  N N   . GLY A 1 79  ? 8.20311   5.31145   -25.57577 1.000 17.00141 ? 79  GLY A N   1 
ATOM   598  C CA  . GLY A 1 79  ? 7.80888   3.99271   -25.11091 1.000 16.72916 ? 79  GLY A CA  1 
ATOM   599  C C   . GLY A 1 79  ? 8.68750   3.47533   -23.98466 1.000 17.17284 ? 79  GLY A C   1 
ATOM   600  O O   . GLY A 1 79  ? 8.18665   3.08612   -22.92933 1.000 17.59068 ? 79  GLY A O   1 
ATOM   601  N N   . GLN A 1 80  ? 10.00886  3.46222   -24.19719 1.000 17.05995 ? 80  GLN A N   1 
ATOM   602  C CA  . GLN A 1 80  ? 10.93024  2.98212   -23.16784 1.000 14.24664 ? 80  GLN A CA  1 
ATOM   603  C C   . GLN A 1 80  ? 10.81984  3.80551   -21.90060 1.000 15.87414 ? 80  GLN A C   1 
ATOM   604  O O   . GLN A 1 80  ? 10.73515  3.26220   -20.79817 1.000 13.86641 ? 80  GLN A O   1 
ATOM   605  C CB  . GLN A 1 80  ? 12.37214  3.02160   -23.65451 1.000 15.50231 ? 80  GLN A CB  1 
ATOM   606  C CG  . GLN A 1 80  ? 12.58324  2.64451   -25.07571 1.000 19.30094 ? 80  GLN A CG  1 
ATOM   607  C CD  . GLN A 1 80  ? 14.04669  2.64725   -25.39576 1.000 27.58853 ? 80  GLN A CD  1 
ATOM   608  O OE1 . GLN A 1 80  ? 14.88314  2.42290   -24.51315 1.000 22.55251 ? 80  GLN A OE1 1 
ATOM   609  N NE2 . GLN A 1 80  ? 14.37747  2.90949   -26.65282 1.000 24.18846 ? 80  GLN A NE2 1 
ATOM   610  N N   . LEU A 1 81  ? 10.83462  5.12644   -22.03794 1.000 17.80374 ? 81  LEU A N   1 
ATOM   611  C CA  . LEU A 1 81  ? 10.66919  5.97853   -20.86939 1.000 16.96180 ? 81  LEU A CA  1 
ATOM   612  C C   . LEU A 1 81  ? 9.42911   5.57705   -20.07128 1.000 17.96353 ? 81  LEU A C   1 
ATOM   613  O O   . LEU A 1 81  ? 9.50514   5.35068   -18.85939 1.000 17.80745 ? 81  LEU A O   1 
ATOM   614  C CB  . LEU A 1 81  ? 10.59207  7.42808   -21.31473 1.000 16.58253 ? 81  LEU A CB  1 
ATOM   615  C CG  . LEU A 1 81  ? 10.62460  8.52716   -20.25752 1.000 20.80909 ? 81  LEU A CG  1 
ATOM   616  C CD1 . LEU A 1 81  ? 11.70351  8.26557   -19.26650 1.000 17.87248 ? 81  LEU A CD1 1 
ATOM   617  C CD2 . LEU A 1 81  ? 10.84060  9.87944   -20.95422 1.000 18.43341 ? 81  LEU A CD2 1 
ATOM   618  N N   . ALA A 1 82  ? 8.28444   5.45516   -20.75086 1.000 11.65026 ? 82  ALA A N   1 
ATOM   619  C CA  . ALA A 1 82  ? 7.05095   5.05350   -20.09114 1.000 13.56115 ? 82  ALA A CA  1 
ATOM   620  C C   . ALA A 1 82  ? 7.15562   3.64941   -19.50842 1.000 20.55571 ? 82  ALA A C   1 
ATOM   621  O O   . ALA A 1 82  ? 6.53881   3.35685   -18.47486 1.000 20.14682 ? 82  ALA A O   1 
ATOM   622  C CB  . ALA A 1 82  ? 5.88562   5.12435   -21.08192 1.000 20.50366 ? 82  ALA A CB  1 
ATOM   623  N N   . GLN A 1 83  ? 7.93461   2.77128   -20.15332 1.000 18.91409 ? 83  GLN A N   1 
ATOM   624  C CA  . GLN A 1 83  ? 8.11052   1.41430   -19.64643 1.000 17.94395 ? 83  GLN A CA  1 
ATOM   625  C C   . GLN A 1 83  ? 8.93924   1.42697   -18.37620 1.000 20.89954 ? 83  GLN A C   1 
ATOM   626  O O   . GLN A 1 83  ? 8.57653   0.78287   -17.38061 1.000 23.33355 ? 83  GLN A O   1 
ATOM   627  C CB  . GLN A 1 83  ? 8.77610   0.53248   -20.71067 1.000 18.80427 ? 83  GLN A CB  1 
ATOM   628  C CG  . GLN A 1 83  ? 8.83213   -0.94260  -20.35987 1.000 19.18216 ? 83  GLN A CG  1 
ATOM   629  C CD  . GLN A 1 83  ? 7.45836   -1.59775  -20.43217 1.000 26.87516 ? 83  GLN A CD  1 
ATOM   630  O OE1 . GLN A 1 83  ? 6.87130   -1.70553  -21.51458 1.000 34.82957 ? 83  GLN A OE1 1 
ATOM   631  N NE2 . GLN A 1 83  ? 6.92970   -2.01574  -19.27974 1.000 20.35635 ? 83  GLN A NE2 1 
ATOM   632  N N   . ARG A 1 84  ? 10.03403  2.19472   -18.38474 1.000 19.52099 ? 84  ARG A N   1 
ATOM   633  C CA  . ARG A 1 84  ? 10.92576  2.26094   -17.23422 1.000 19.86921 ? 84  ARG A CA  1 
ATOM   634  C C   . ARG A 1 84  ? 10.28009  2.99067   -16.06905 1.000 29.53821 ? 84  ARG A C   1 
ATOM   635  O O   . ARG A 1 84  ? 10.55418  2.68045   -14.90059 1.000 30.71340 ? 84  ARG A O   1 
ATOM   636  C CB  . ARG A 1 84  ? 12.22200  2.93965   -17.61965 1.000 21.32078 ? 84  ARG A CB  1 
ATOM   637  C CG  . ARG A 1 84  ? 12.78148  3.80365   -16.52102 1.000 29.60927 ? 84  ARG A CG  1 
ATOM   638  C CD  . ARG A 1 84  ? 14.27136  3.84459   -16.58263 1.000 37.89012 ? 84  ARG A CD  1 
ATOM   639  N NE  . ARG A 1 84  ? 14.84033  2.79927   -15.74520 1.000 45.62043 ? 84  ARG A NE  1 
ATOM   640  C CZ  . ARG A 1 84  ? 16.14072  2.61664   -15.57822 1.000 53.93627 ? 84  ARG A CZ  1 
ATOM   641  N NH1 . ARG A 1 84  ? 17.02466  3.34707   -16.23790 1.000 62.10093 ? 84  ARG A NH1 1 
ATOM   642  N NH2 . ARG A 1 84  ? 16.56466  1.69238   -14.71555 1.000 52.70685 ? 84  ARG A NH2 1 
ATOM   643  N N   . ILE A 1 85  ? 9.41370   3.95426   -16.36174 1.000 27.96849 ? 85  ILE A N   1 
ATOM   644  C CA  . ILE A 1 85  ? 8.58271   4.51681   -15.30953 1.000 22.35407 ? 85  ILE A CA  1 
ATOM   645  C C   . ILE A 1 85  ? 7.70121   3.42336   -14.70930 1.000 26.17353 ? 85  ILE A C   1 
ATOM   646  O O   . ILE A 1 85  ? 7.74279   3.17490   -13.50429 1.000 27.13955 ? 85  ILE A O   1 
ATOM   647  C CB  . ILE A 1 85  ? 7.78107   5.70996   -15.85791 1.000 19.86093 ? 85  ILE A CB  1 
ATOM   648  C CG1 . ILE A 1 85  ? 8.72912   6.90199   -16.08545 1.000 18.08101 ? 85  ILE A CG1 1 
ATOM   649  C CG2 . ILE A 1 85  ? 6.64135   6.07764   -14.95013 1.000 18.02388 ? 85  ILE A CG2 1 
ATOM   650  C CD1 . ILE A 1 85  ? 8.02446   8.20033   -16.44309 1.000 12.90407 ? 85  ILE A CD1 1 
ATOM   651  N N   . VAL A 1 86  ? 6.96260   2.69152   -15.55583 1.000 27.28335 ? 86  VAL A N   1 
ATOM   652  C CA  . VAL A 1 86  ? 6.08623   1.61723   -15.06908 1.000 24.63876 ? 86  VAL A CA  1 
ATOM   653  C C   . VAL A 1 86  ? 6.84156   0.65446   -14.15131 1.000 21.34882 ? 86  VAL A C   1 
ATOM   654  O O   . VAL A 1 86  ? 6.40089   0.35344   -13.03768 1.000 25.67761 ? 86  VAL A O   1 
ATOM   655  C CB  . VAL A 1 86  ? 5.45183   0.86308   -16.25430 1.000 26.00344 ? 86  VAL A CB  1 
ATOM   656  C CG1 . VAL A 1 86  ? 5.00241   -0.54713  -15.82657 1.000 23.87135 ? 86  VAL A CG1 1 
ATOM   657  C CG2 . VAL A 1 86  ? 4.27439   1.63066   -16.82225 1.000 19.22065 ? 86  VAL A CG2 1 
ATOM   658  N N   . ASP A 1 87  ? 7.97831   0.13755   -14.61818 1.000 22.95463 ? 87  ASP A N   1 
ATOM   659  C CA  . ASP A 1 87  ? 8.74628   -0.81212  -13.81819 1.000 25.13184 ? 87  ASP A CA  1 
ATOM   660  C C   . ASP A 1 87  ? 9.26138   -0.17131  -12.52383 1.000 25.50039 ? 87  ASP A C   1 
ATOM   661  O O   . ASP A 1 87  ? 9.07469   -0.72255  -11.43453 1.000 22.66880 ? 87  ASP A O   1 
ATOM   662  C CB  . ASP A 1 87  ? 9.91357   -1.37026  -14.63392 1.000 22.70403 ? 87  ASP A CB  1 
ATOM   663  C CG  . ASP A 1 87  ? 9.46995   -2.09146  -15.92579 1.000 33.73464 ? 87  ASP A CG  1 
ATOM   664  O OD1 . ASP A 1 87  ? 8.33343   -2.61328  -16.00094 1.000 34.57710 ? 87  ASP A OD1 1 
ATOM   665  O OD2 . ASP A 1 87  ? 10.28113  -2.14237  -16.87812 1.000 33.09371 ? 87  ASP A OD2 1 
ATOM   666  N N   . ASP A 1 88  ? 9.91702   0.99575   -12.62872 1.000 19.84966 ? 88  ASP A N   1 
ATOM   667  C CA  . ASP A 1 88  ? 10.60530  1.58613   -11.47970 1.000 26.34867 ? 88  ASP A CA  1 
ATOM   668  C C   . ASP A 1 88  ? 9.63215   2.07444   -10.41642 1.000 33.49806 ? 88  ASP A C   1 
ATOM   669  O O   . ASP A 1 88  ? 9.96765   2.06749   -9.21754  1.000 24.05000 ? 88  ASP A O   1 
ATOM   670  C CB  . ASP A 1 88  ? 11.48390  2.76977   -11.90530 1.000 31.53733 ? 88  ASP A CB  1 
ATOM   671  C CG  . ASP A 1 88  ? 12.61227  2.37684   -12.84151 1.000 35.37454 ? 88  ASP A CG  1 
ATOM   672  O OD1 . ASP A 1 88  ? 12.78955  1.16965   -13.12309 1.000 40.09971 ? 88  ASP A OD1 1 
ATOM   673  O OD2 . ASP A 1 88  ? 13.32356  3.29813   -13.30161 1.000 32.76427 ? 88  ASP A OD2 1 
ATOM   674  N N   . VAL A 1 89  ? 8.45365   2.55039   -10.84182 1.000 26.02063 ? 89  VAL A N   1 
ATOM   675  C CA  . VAL A 1 89  ? 7.44728   2.99736   -9.88860  1.000 23.64311 ? 89  VAL A CA  1 
ATOM   676  C C   . VAL A 1 89  ? 6.80998   1.80714   -9.19418  1.000 23.50781 ? 89  VAL A C   1 
ATOM   677  O O   . VAL A 1 89  ? 6.58887   1.82514   -7.97526  1.000 20.82023 ? 89  VAL A O   1 
ATOM   678  C CB  . VAL A 1 89  ? 6.39435   3.86555   -10.59283 1.000 24.10102 ? 89  VAL A CB  1 
ATOM   679  C CG1 . VAL A 1 89  ? 5.32072   4.27974   -9.60095  1.000 19.18149 ? 89  VAL A CG1 1 
ATOM   680  C CG2 . VAL A 1 89  ? 7.06789   5.07552   -11.27807 1.000 21.52817 ? 89  VAL A CG2 1 
ATOM   681  N N   . SER A 1 90  ? 6.48043   0.76501   -9.96607  1.000 30.27111 ? 90  SER A N   1 
ATOM   682  C CA  . SER A 1 90  ? 6.05758   -0.50673  -9.38351  1.000 25.23652 ? 90  SER A CA  1 
ATOM   683  C C   . SER A 1 90  ? 6.97767   -0.92462  -8.25310  1.000 27.20413 ? 90  SER A C   1 
ATOM   684  O O   . SER A 1 90  ? 6.51917   -1.39915  -7.20303  1.000 22.14325 ? 90  SER A O   1 
ATOM   685  C CB  . SER A 1 90  ? 6.04716   -1.58841  -10.45334 1.000 28.58223 ? 90  SER A CB  1 
ATOM   686  O OG  . SER A 1 90  ? 6.00087   -2.87714  -9.87572  1.000 34.48800 ? 90  SER A OG  1 
ATOM   687  N N   . VAL A 1 91  ? 8.28377   -0.72723  -8.44190  1.000 26.21038 ? 91  VAL A N   1 
ATOM   688  C CA  . VAL A 1 91  ? 9.25063   -1.19826  -7.45669  1.000 24.78568 ? 91  VAL A CA  1 
ATOM   689  C C   . VAL A 1 91  ? 9.39874   -0.20766  -6.30606  1.000 23.50691 ? 91  VAL A C   1 
ATOM   690  O O   . VAL A 1 91  ? 9.47653   -0.61101  -5.13991  1.000 22.27098 ? 91  VAL A O   1 
ATOM   691  C CB  . VAL A 1 91  ? 10.58673  -1.50224  -8.15207  1.000 21.18908 ? 91  VAL A CB  1 
ATOM   692  C CG1 . VAL A 1 91  ? 11.73671  -1.55672  -7.14654  1.000 22.02700 ? 91  VAL A CG1 1 
ATOM   693  C CG2 . VAL A 1 91  ? 10.46971  -2.81489  -8.90671  1.000 16.70502 ? 91  VAL A CG2 1 
ATOM   694  N N   . ALA A 1 92  ? 9.41880   1.09826   -6.59984  1.000 24.98665 ? 92  ALA A N   1 
ATOM   695  C CA  . ALA A 1 92  ? 9.58590   2.08191   -5.53324  1.000 19.40601 ? 92  ALA A CA  1 
ATOM   696  C C   . ALA A 1 92  ? 8.35480   2.14586   -4.62711  1.000 21.96607 ? 92  ALA A C   1 
ATOM   697  O O   . ALA A 1 92  ? 8.48845   2.20908   -3.39993  1.000 25.14148 ? 92  ALA A O   1 
ATOM   698  C CB  . ALA A 1 92  ? 9.89879   3.45614   -6.12270  1.000 23.96229 ? 92  ALA A CB  1 
ATOM   699  N N   . ALA A 1 93  ? 7.14910   2.12659   -5.20250  1.000 19.54954 ? 93  ALA A N   1 
ATOM   700  C CA  . ALA A 1 93  ? 5.94004   2.20119   -4.38760  1.000 25.10485 ? 93  ALA A CA  1 
ATOM   701  C C   . ALA A 1 93  ? 5.51482   0.85419   -3.79720  1.000 22.02712 ? 93  ALA A C   1 
ATOM   702  O O   . ALA A 1 93  ? 4.65212   0.83891   -2.91643  1.000 29.21670 ? 93  ALA A O   1 
ATOM   703  C CB  . ALA A 1 93  ? 4.77855   2.79138   -5.20029  1.000 17.54304 ? 93  ALA A CB  1 
ATOM   704  N N   . GLU A 1 94  ? 6.09756   -0.25842  -4.24566  1.000 18.57894 ? 94  GLU A N   1 
ATOM   705  C CA  . GLU A 1 94  ? 5.75616   -1.59816  -3.74814  1.000 26.12733 ? 94  GLU A CA  1 
ATOM   706  C C   . GLU A 1 94  ? 4.32003   -1.94743  -4.13738  1.000 26.48552 ? 94  GLU A C   1 
ATOM   707  O O   . GLU A 1 94  ? 3.49584   -2.33541  -3.31079  1.000 23.02868 ? 94  GLU A O   1 
ATOM   708  C CB  . GLU A 1 94  ? 5.99401   -1.73463  -2.23071  1.000 30.04135 ? 94  GLU A CB  1 
ATOM   709  C CG  . GLU A 1 94  ? 7.46821   -1.99601  -1.87095  1.000 28.71441 ? 94  GLU A CG  1 
ATOM   710  C CD  . GLU A 1 94  ? 7.77472   -2.21542  -0.37542  1.000 35.33947 ? 94  GLU A CD  1 
ATOM   711  O OE1 . GLU A 1 94  ? 6.95344   -1.84353  0.50450   1.000 35.02171 ? 94  GLU A OE1 1 
ATOM   712  O OE2 . GLU A 1 94  ? 8.87482   -2.75464  -0.08610  1.000 32.07982 ? 94  GLU A OE2 1 
ATOM   713  N N   . ILE A 1 95  ? 4.03452   -1.80697  -5.43062  1.000 26.19219 ? 95  ILE A N   1 
ATOM   714  C CA  . ILE A 1 95  ? 2.68717   -1.91658  -5.95912  1.000 25.34895 ? 95  ILE A CA  1 
ATOM   715  C C   . ILE A 1 95  ? 2.76384   -2.66432  -7.28173  1.000 27.49422 ? 95  ILE A C   1 
ATOM   716  O O   . ILE A 1 95  ? 3.75981   -2.57334  -8.00434  1.000 30.31628 ? 95  ILE A O   1 
ATOM   717  C CB  . ILE A 1 95  ? 2.05924   -0.51653  -6.11567  1.000 23.16903 ? 95  ILE A CB  1 
ATOM   718  C CG1 . ILE A 1 95  ? 0.57727   -0.60289  -6.49478  1.000 33.65631 ? 95  ILE A CG1 1 
ATOM   719  C CG2 . ILE A 1 95  ? 2.82604   0.28233   -7.15284  1.000 26.79645 ? 95  ILE A CG2 1 
ATOM   720  C CD1 . ILE A 1 95  ? -0.20257  0.68881   -6.20013  1.000 29.40632 ? 95  ILE A CD1 1 
ATOM   721  N N   . ASP A 1 96  ? 1.72687   -3.45025  -7.57959  1.000 27.51138 ? 96  ASP A N   1 
ATOM   722  C CA  . ASP A 1 96  ? 1.71030   -4.18638  -8.83858  1.000 22.01297 ? 96  ASP A CA  1 
ATOM   723  C C   . ASP A 1 96  ? 1.67004   -3.19476  -10.01198 1.000 24.83163 ? 96  ASP A C   1 
ATOM   724  O O   . ASP A 1 96  ? 1.27385   -2.03173  -9.87201  1.000 22.94833 ? 96  ASP A O   1 
ATOM   725  C CB  . ASP A 1 96  ? 0.52732   -5.15904  -8.85631  1.000 17.92193 ? 96  ASP A CB  1 
ATOM   726  C CG  . ASP A 1 96  ? 0.59662   -6.21283  -9.98884  1.000 31.12904 ? 96  ASP A CG  1 
ATOM   727  O OD1 . ASP A 1 96  ? 0.54983   -5.86721  -11.19014 1.000 28.52694 ? 96  ASP A OD1 1 
ATOM   728  O OD2 . ASP A 1 96  ? 0.65064   -7.41847  -9.67444  1.000 36.96791 ? 96  ASP A OD2 1 
ATOM   729  N N   . ARG A 1 97  ? 2.14077   -3.65203  -11.17321 1.000 22.33763 ? 97  ARG A N   1 
ATOM   730  C CA  . ARG A 1 97  ? 2.11315   -2.79770  -12.35750 1.000 28.88317 ? 97  ARG A CA  1 
ATOM   731  C C   . ARG A 1 97  ? 0.70641   -2.63164  -12.92402 1.000 23.65994 ? 97  ARG A C   1 
ATOM   732  O O   . ARG A 1 97  ? 0.42615   -1.62993  -13.58493 1.000 22.61902 ? 97  ARG A O   1 
ATOM   733  C CB  . ARG A 1 97  ? 3.03857   -3.35007  -13.43359 1.000 21.88338 ? 97  ARG A CB  1 
ATOM   734  C CG  . ARG A 1 97  ? 4.50045   -3.18204  -13.11168 1.000 27.19691 ? 97  ARG A CG  1 
ATOM   735  C CD  . ARG A 1 97  ? 5.33791   -3.85739  -14.17393 1.000 32.42493 ? 97  ARG A CD  1 
ATOM   736  N NE  . ARG A 1 97  ? 6.76605   -3.80232  -13.89488 1.000 34.72067 ? 97  ARG A NE  1 
ATOM   737  C CZ  . ARG A 1 97  ? 7.36548   -4.37584  -12.85736 1.000 38.30947 ? 97  ARG A CZ  1 
ATOM   738  N NH1 . ARG A 1 97  ? 6.67353   -4.93798  -11.87414 1.000 30.72928 ? 97  ARG A NH1 1 
ATOM   739  N NH2 . ARG A 1 97  ? 8.69621   -4.37989  -12.80249 1.000 37.57802 ? 97  ARG A NH2 1 
ATOM   740  N N   . LYS A 1 98  ? -0.18503  -3.58742  -12.69656 1.000 20.87205 ? 98  LYS A N   1 
ATOM   741  C CA  . LYS A 1 98  ? -1.52066  -3.42762  -13.25127 1.000 21.49631 ? 98  LYS A CA  1 
ATOM   742  C C   . LYS A 1 98  ? -2.31209  -2.35281  -12.51768 1.000 24.48155 ? 98  LYS A C   1 
ATOM   743  O O   . LYS A 1 98  ? -3.44812  -2.06709  -12.90728 1.000 25.70401 ? 98  LYS A O   1 
ATOM   744  C CB  . LYS A 1 98  ? -2.26970  -4.77104  -13.24427 1.000 22.56440 ? 98  LYS A CB  1 
ATOM   745  C CG  . LYS A 1 98  ? -1.79261  -5.83509  -14.31480 1.000 37.83519 ? 98  LYS A CG  1 
ATOM   746  C CD  . LYS A 1 98  ? -0.36398  -6.38236  -14.04687 1.000 30.66404 ? 98  LYS A CD  1 
ATOM   747  C CE  . LYS A 1 98  ? -0.19062  -7.87358  -14.32798 1.000 40.13530 ? 98  LYS A CE  1 
ATOM   748  N NZ  . LYS A 1 98  ? 1.11375   -8.35830  -13.74991 1.000 36.34100 ? 98  LYS A NZ  1 
ATOM   749  N N   . HIS A 1 99  ? -1.72491  -1.75037  -11.48625 1.000 22.43848 ? 99  HIS A N   1 
ATOM   750  C CA  . HIS A 1 99  ? -2.24885  -0.56478  -10.82883 1.000 25.44914 ? 99  HIS A CA  1 
ATOM   751  C C   . HIS A 1 99  ? -1.70071  0.75031   -11.39344 1.000 22.70289 ? 99  HIS A C   1 
ATOM   752  O O   . HIS A 1 99  ? -2.10156  1.81924   -10.92289 1.000 22.87777 ? 99  HIS A O   1 
ATOM   753  C CB  . HIS A 1 99  ? -1.92968  -0.61775  -9.33569  1.000 19.89271 ? 99  HIS A CB  1 
ATOM   754  C CG  . HIS A 1 99  ? -2.76258  -1.58989  -8.56741  1.000 28.48018 ? 99  HIS A CG  1 
ATOM   755  N ND1 . HIS A 1 99  ? -4.05821  -1.90196  -8.91521  1.000 25.55683 ? 99  HIS A ND1 1 
ATOM   756  C CD2 . HIS A 1 99  ? -2.48252  -2.31951  -7.46335  1.000 25.00860 ? 99  HIS A CD2 1 
ATOM   757  C CE1 . HIS A 1 99  ? -4.54315  -2.77559  -8.05325  1.000 19.30309 ? 99  HIS A CE1 1 
ATOM   758  N NE2 . HIS A 1 99  ? -3.60715  -3.04658  -7.16342  1.000 24.43674 ? 99  HIS A NE2 1 
ATOM   759  N N   . ILE A 1 100 ? -0.78070  0.71775   -12.35019 1.000 18.36959 ? 100 ILE A N   1 
ATOM   760  C CA  . ILE A 1 100 ? -0.06439  1.91808   -12.77718 1.000 19.36467 ? 100 ILE A CA  1 
ATOM   761  C C   . ILE A 1 100 ? -0.53121  2.35536   -14.16029 1.000 15.25243 ? 100 ILE A C   1 
ATOM   762  O O   . ILE A 1 100 ? -0.53397  1.55995   -15.11356 1.000 18.89931 ? 100 ILE A O   1 
ATOM   763  C CB  . ILE A 1 100 ? 1.45477   1.70993   -12.77246 1.000 18.17261 ? 100 ILE A CB  1 
ATOM   764  C CG1 . ILE A 1 100 ? 1.88384   1.03111   -11.45995 1.000 27.74149 ? 100 ILE A CG1 1 
ATOM   765  C CG2 . ILE A 1 100 ? 2.16047   3.06765   -12.99376 1.000 14.84647 ? 100 ILE A CG2 1 
ATOM   766  C CD1 . ILE A 1 100 ? 3.38498   0.78846   -11.33693 1.000 27.31898 ? 100 ILE A CD1 1 
ATOM   767  N N   . TRP A 1 101 ? -0.87448  3.63285   -14.27196 1.000 14.52070 ? 101 TRP A N   1 
ATOM   768  C CA  . TRP A 1 101 ? -1.37480  4.23697   -15.50095 1.000 18.37041 ? 101 TRP A CA  1 
ATOM   769  C C   . TRP A 1 101 ? -0.44333  5.36512   -15.91012 1.000 18.61725 ? 101 TRP A C   1 
ATOM   770  O O   . TRP A 1 101 ? -0.15228  6.24748   -15.10500 1.000 17.02753 ? 101 TRP A O   1 
ATOM   771  C CB  . TRP A 1 101 ? -2.79589  4.77332   -15.30469 1.000 14.66988 ? 101 TRP A CB  1 
ATOM   772  C CG  . TRP A 1 101 ? -3.80816  3.70136   -15.23399 1.000 15.88941 ? 101 TRP A CG  1 
ATOM   773  C CD1 . TRP A 1 101 ? -3.71555  2.52618   -14.54296 1.000 18.42517 ? 101 TRP A CD1 1 
ATOM   774  C CD2 . TRP A 1 101 ? -5.07169  3.68509   -15.88988 1.000 17.40950 ? 101 TRP A CD2 1 
ATOM   775  N NE1 . TRP A 1 101 ? -4.85160  1.77600   -14.72291 1.000 22.07534 ? 101 TRP A NE1 1 
ATOM   776  C CE2 . TRP A 1 101 ? -5.70484  2.46648   -15.54672 1.000 23.96407 ? 101 TRP A CE2 1 
ATOM   777  C CE3 . TRP A 1 101 ? -5.73570  4.58145   -16.73258 1.000 16.17962 ? 101 TRP A CE3 1 
ATOM   778  C CZ2 . TRP A 1 101 ? -6.96597  2.11502   -16.03153 1.000 19.38884 ? 101 TRP A CZ2 1 
ATOM   779  C CZ3 . TRP A 1 101 ? -6.99035  4.24369   -17.19696 1.000 17.98673 ? 101 TRP A CZ3 1 
ATOM   780  C CH2 . TRP A 1 101 ? -7.59165  3.01201   -16.85230 1.000 23.07662 ? 101 TRP A CH2 1 
ATOM   781  N N   . VAL A 1 102 ? 0.01687   5.35190   -17.15848 1.000 19.67167 ? 102 VAL A N   1 
ATOM   782  C CA  . VAL A 1 102 ? 0.98933   6.33951   -17.61035 1.000 15.59189 ? 102 VAL A CA  1 
ATOM   783  C C   . VAL A 1 102 ? 0.53540   6.93941   -18.93356 1.000 14.03473 ? 102 VAL A C   1 
ATOM   784  O O   . VAL A 1 102 ? 0.35582   6.21677   -19.90827 1.000 13.40139 ? 102 VAL A O   1 
ATOM   785  C CB  . VAL A 1 102 ? 2.39682   5.73430   -17.72363 1.000 14.80469 ? 102 VAL A CB  1 
ATOM   786  C CG1 . VAL A 1 102 ? 3.42070   6.80343   -18.10384 1.000 16.16782 ? 102 VAL A CG1 1 
ATOM   787  C CG2 . VAL A 1 102 ? 2.79368   5.11335   -16.38908 1.000 16.19350 ? 102 VAL A CG2 1 
ATOM   788  N N   . PHE A 1 103 ? 0.36420   8.26366   -18.96480 1.000 14.71451 ? 103 PHE A N   1 
ATOM   789  C CA  . PHE A 1 103 ? 0.16181   9.03494   -20.18760 1.000 13.67001 ? 103 PHE A CA  1 
ATOM   790  C C   . PHE A 1 103 ? 1.24700   10.10189  -20.28921 1.000 18.23475 ? 103 PHE A C   1 
ATOM   791  O O   . PHE A 1 103 ? 1.49043   10.82558  -19.31189 1.000 16.79111 ? 103 PHE A O   1 
ATOM   792  C CB  . PHE A 1 103 ? -1.19788  9.77239   -20.22335 1.000 11.23293 ? 103 PHE A CB  1 
ATOM   793  C CG  . PHE A 1 103 ? -2.41604  8.89664   -20.33062 1.000 12.26719 ? 103 PHE A CG  1 
ATOM   794  C CD1 . PHE A 1 103 ? -2.32042  7.51435   -20.45357 1.000 15.39265 ? 103 PHE A CD1 1 
ATOM   795  C CD2 . PHE A 1 103 ? -3.68778  9.48502   -20.32513 1.000 16.20310 ? 103 PHE A CD2 1 
ATOM   796  C CE1 . PHE A 1 103 ? -3.46859  6.72480   -20.54753 1.000 16.24781 ? 103 PHE A CE1 1 
ATOM   797  C CE2 . PHE A 1 103 ? -4.85616  8.70686   -20.43162 1.000 14.89493 ? 103 PHE A CE2 1 
ATOM   798  C CZ  . PHE A 1 103 ? -4.74242  7.32471   -20.53322 1.000 18.47148 ? 103 PHE A CZ  1 
ATOM   799  N N   . PHE A 1 104 ? 1.86353   10.23993  -21.47801 1.000 12.86328 ? 104 PHE A N   1 
ATOM   800  C CA  . PHE A 1 104 ? 2.73166   11.37458  -21.79682 1.000 11.75397 ? 104 PHE A CA  1 
ATOM   801  C C   . PHE A 1 104 ? 2.03028   12.30012  -22.78242 1.000 21.08364 ? 104 PHE A C   1 
ATOM   802  O O   . PHE A 1 104 ? 1.63121   11.86614  -23.87236 1.000 27.57694 ? 104 PHE A O   1 
ATOM   803  C CB  . PHE A 1 104 ? 4.06638   10.96924  -22.42592 1.000 16.08036 ? 104 PHE A CB  1 
ATOM   804  C CG  . PHE A 1 104 ? 4.97117   10.16449  -21.55457 1.000 16.30409 ? 104 PHE A CG  1 
ATOM   805  C CD1 . PHE A 1 104 ? 4.70576   9.97297   -20.21040 1.000 21.13966 ? 104 PHE A CD1 1 
ATOM   806  C CD2 . PHE A 1 104 ? 6.11815   9.60513   -22.09165 1.000 15.60409 ? 104 PHE A CD2 1 
ATOM   807  C CE1 . PHE A 1 104 ? 5.56410   9.21488   -19.40621 1.000 20.34580 ? 104 PHE A CE1 1 
ATOM   808  C CE2 . PHE A 1 104 ? 6.98611   8.84959   -21.30015 1.000 24.66682 ? 104 PHE A CE2 1 
ATOM   809  C CZ  . PHE A 1 104 ? 6.70713   8.65327   -19.95039 1.000 16.85998 ? 104 PHE A CZ  1 
ATOM   810  N N   . GLY A 1 105 ? 1.93415   13.58054  -22.43011 1.000 16.66462 ? 105 GLY A N   1 
ATOM   811  C CA  . GLY A 1 105 ? 1.70177   14.62567  -23.40069 1.000 22.73288 ? 105 GLY A CA  1 
ATOM   812  C C   . GLY A 1 105 ? 2.98829   15.37376  -23.72855 1.000 21.80259 ? 105 GLY A C   1 
ATOM   813  O O   . GLY A 1 105 ? 3.99018   15.25182  -23.01759 1.000 21.35642 ? 105 GLY A O   1 
ATOM   814  N N   . GLU A 1 106 ? 2.95074   16.12626  -24.83765 1.000 15.80746 ? 106 GLU A N   1 
ATOM   815  C CA  . GLU A 1 106 ? 4.06826   16.94467  -25.30184 1.000 15.51735 ? 106 GLU A CA  1 
ATOM   816  C C   . GLU A 1 106 ? 3.57426   18.28503  -25.84660 1.000 18.67905 ? 106 GLU A C   1 
ATOM   817  O O   . GLU A 1 106 ? 2.49720   18.38130  -26.44484 1.000 15.25981 ? 106 GLU A O   1 
ATOM   818  C CB  . GLU A 1 106 ? 4.88136   16.24237  -26.41298 1.000 18.74173 ? 106 GLU A CB  1 
ATOM   819  C CG  . GLU A 1 106 ? 4.93786   14.72908  -26.31662 1.000 21.18110 ? 106 GLU A CG  1 
ATOM   820  C CD  . GLU A 1 106 ? 5.11063   14.04518  -27.66017 1.000 20.76938 ? 106 GLU A CD  1 
ATOM   821  O OE1 . GLU A 1 106 ? 6.19443   14.18999  -28.27160 1.000 20.07326 ? 106 GLU A OE1 1 
ATOM   822  O OE2 . GLU A 1 106 ? 4.15693   13.35509  -28.09404 1.000 20.57903 ? 106 GLU A OE2 1 
ATOM   823  N N   . MET A 1 107 ? 4.42381   19.29580  -25.70601 1.000 19.86273 ? 107 MET A N   1 
ATOM   824  C CA  . MET A 1 107 ? 4.18328   20.66425  -26.13218 1.000 20.01895 ? 107 MET A CA  1 
ATOM   825  C C   . MET A 1 107 ? 5.47163   21.21338  -26.73572 1.000 18.65835 ? 107 MET A C   1 
ATOM   826  O O   . MET A 1 107 ? 6.55274   20.65026  -26.52890 1.000 19.97797 ? 107 MET A O   1 
ATOM   827  C CB  . MET A 1 107 ? 3.72760   21.56241  -24.96401 1.000 14.30723 ? 107 MET A CB  1 
ATOM   828  C CG  . MET A 1 107 ? 2.57332   21.04340  -24.09411 1.000 25.72572 ? 107 MET A CG  1 
ATOM   829  S SD  . MET A 1 107 ? 2.70137   21.56118  -22.31557 1.000 22.99113 ? 107 MET A SD  1 
ATOM   830  C CE  . MET A 1 107 ? 4.10728   20.55158  -21.79437 1.000 25.25944 ? 107 MET A CE  1 
ATOM   831  N N   . PRO A 1 108 ? 5.38720   22.29149  -27.50344 1.000 14.59697 ? 108 PRO A N   1 
ATOM   832  C CA  . PRO A 1 108 ? 6.61323   22.98290  -27.94044 1.000 19.60138 ? 108 PRO A CA  1 
ATOM   833  C C   . PRO A 1 108 ? 7.38586   23.50739  -26.74399 1.000 18.17925 ? 108 PRO A C   1 
ATOM   834  O O   . PRO A 1 108 ? 6.80901   24.08262  -25.82504 1.000 22.93336 ? 108 PRO A O   1 
ATOM   835  C CB  . PRO A 1 108 ? 6.08879   24.13391  -28.80967 1.000 18.01685 ? 108 PRO A CB  1 
ATOM   836  C CG  . PRO A 1 108 ? 4.74011   23.71095  -29.23125 1.000 20.21877 ? 108 PRO A CG  1 
ATOM   837  C CD  . PRO A 1 108 ? 4.18163   22.80811  -28.16676 1.000 14.10723 ? 108 PRO A CD  1 
ATOM   838  N N   . ALA A 1 109 ? 8.69843   23.28702  -26.74528 1.000 16.00821 ? 109 ALA A N   1 
ATOM   839  C CA  . ALA A 1 109 ? 9.53755   23.88785  -25.71386 1.000 20.09361 ? 109 ALA A CA  1 
ATOM   840  C C   . ALA A 1 109 ? 9.32283   25.39744  -25.63410 1.000 21.44477 ? 109 ALA A C   1 
ATOM   841  O O   . ALA A 1 109 ? 9.39015   25.99287  -24.54969 1.000 19.82449 ? 109 ALA A O   1 
ATOM   842  C CB  . ALA A 1 109 ? 11.00654  23.56370  -25.98178 1.000 23.20751 ? 109 ALA A CB  1 
ATOM   843  N N   . GLN A 1 110 ? 9.02898   26.01510  -26.77069 1.000 18.33286 ? 110 GLN A N   1 
ATOM   844  C CA  . GLN A 1 110 ? 8.74118   27.43494  -26.83178 1.000 28.41873 ? 110 GLN A CA  1 
ATOM   845  C C   . GLN A 1 110 ? 7.55791   27.85067  -25.96157 1.000 22.11519 ? 110 GLN A C   1 
ATOM   846  O O   . GLN A 1 110 ? 7.45230   29.03904  -25.64519 1.000 19.58534 ? 110 GLN A O   1 
ATOM   847  C CB  . GLN A 1 110 ? 8.50666   27.84413  -28.29444 1.000 24.35442 ? 110 GLN A CB  1 
ATOM   848  C CG  . GLN A 1 110 ? 9.80240   28.09061  -29.06221 1.000 31.76031 ? 110 GLN A CG  1 
ATOM   849  C CD  . GLN A 1 110 ? 10.01802  27.12192  -30.20907 1.000 38.59028 ? 110 GLN A CD  1 
ATOM   850  O OE1 . GLN A 1 110 ? 9.14831   26.94939  -31.06435 1.000 38.66505 ? 110 GLN A OE1 1 
ATOM   851  N NE2 . GLN A 1 110 ? 11.17747  26.46523  -30.22145 1.000 36.36546 ? 110 GLN A NE2 1 
ATOM   852  N N   . GLN A 1 111 ? 6.66211   26.93625  -25.56976 1.000 10.92229 ? 111 GLN A N   1 
ATOM   853  C CA  . GLN A 1 111 ? 5.58604   27.31390  -24.65053 1.000 21.70552 ? 111 GLN A CA  1 
ATOM   854  C C   . GLN A 1 111 ? 5.73540   26.63932  -23.29059 1.000 17.75388 ? 111 GLN A C   1 
ATOM   855  O O   . GLN A 1 111 ? 4.75467   26.27336  -22.63687 1.000 11.59413 ? 111 GLN A O   1 
ATOM   856  C CB  . GLN A 1 111 ? 4.20055   27.04512  -25.23504 1.000 16.73546 ? 111 GLN A CB  1 
ATOM   857  C CG  . GLN A 1 111 ? 3.99179   25.69332  -25.82997 1.000 17.15056 ? 111 GLN A CG  1 
ATOM   858  C CD  . GLN A 1 111 ? 3.01368   25.74028  -27.00789 1.000 19.63524 ? 111 GLN A CD  1 
ATOM   859  O OE1 . GLN A 1 111 ? 3.30993   26.31949  -28.05324 1.000 16.96977 ? 111 GLN A OE1 1 
ATOM   860  N NE2 . GLN A 1 111 ? 1.83837   25.13590  -26.82949 1.000 24.96232 ? 111 GLN A NE2 1 
ATOM   861  N N   . MET A 1 112 ? 6.97353   26.52376  -22.82350 1.000 19.07193 ? 112 MET A N   1 
ATOM   862  C CA  . MET A 1 112 ? 7.23793   25.78444  -21.60031 1.000 16.78747 ? 112 MET A CA  1 
ATOM   863  C C   . MET A 1 112 ? 8.27010   26.50529  -20.75232 1.000 17.46910 ? 112 MET A C   1 
ATOM   864  O O   . MET A 1 112 ? 9.38394   26.78349  -21.20865 1.000 19.49081 ? 112 MET A O   1 
ATOM   865  C CB  . MET A 1 112 ? 7.70324   24.37381  -21.92521 1.000 12.46875 ? 112 MET A CB  1 
ATOM   866  C CG  . MET A 1 112 ? 6.62468   23.52037  -22.51018 1.000 14.83440 ? 112 MET A CG  1 
ATOM   867  S SD  . MET A 1 112 ? 7.21549   21.83873  -22.71277 1.000 23.82458 ? 112 MET A SD  1 
ATOM   868  C CE  . MET A 1 112 ? 8.95017   22.21028  -22.85927 1.000 21.70237 ? 112 MET A CE  1 
ATOM   869  N N   . VAL A 1 113 ? 7.89628   26.75927  -19.50854 1.000 12.28236 ? 113 VAL A N   1 
ATOM   870  C CA  . VAL A 1 113 ? 8.65799   27.57434  -18.58072 1.000 18.89561 ? 113 VAL A CA  1 
ATOM   871  C C   . VAL A 1 113 ? 8.91779   26.73926  -17.33266 1.000 22.99386 ? 113 VAL A C   1 
ATOM   872  O O   . VAL A 1 113 ? 7.97662   26.20339  -16.72146 1.000 17.94402 ? 113 VAL A O   1 
ATOM   873  C CB  . VAL A 1 113 ? 7.90262   28.87538  -18.22482 1.000 18.49556 ? 113 VAL A CB  1 
ATOM   874  C CG1 . VAL A 1 113 ? 8.54849   29.56214  -17.04263 1.000 18.08455 ? 113 VAL A CG1 1 
ATOM   875  C CG2 . VAL A 1 113 ? 7.82392   29.80928  -19.41467 1.000 13.59171 ? 113 VAL A CG2 1 
ATOM   876  N N   . GLU A 1 114 ? 10.19395  26.62723  -16.96626 1.000 24.55665 ? 114 GLU A N   1 
ATOM   877  C CA  . GLU A 1 114 ? 10.62951  26.03722  -15.70740 1.000 21.50133 ? 114 GLU A CA  1 
ATOM   878  C C   . GLU A 1 114 ? 11.64006  26.99081  -15.10001 1.000 26.87274 ? 114 GLU A C   1 
ATOM   879  O O   . GLU A 1 114 ? 12.47811  27.54106  -15.81788 1.000 26.21183 ? 114 GLU A O   1 
ATOM   880  C CB  . GLU A 1 114 ? 11.24662  24.66909  -15.91001 1.000 15.63749 ? 114 GLU A CB  1 
ATOM   881  C CG  . GLU A 1 114 ? 10.33013  23.75964  -16.68622 1.000 23.10248 ? 114 GLU A CG  1 
ATOM   882  C CD  . GLU A 1 114 ? 10.84979  22.35640  -16.78866 1.000 24.57681 ? 114 GLU A CD  1 
ATOM   883  O OE1 . GLU A 1 114 ? 12.02030  22.13313  -16.42601 1.000 26.11856 ? 114 GLU A OE1 1 
ATOM   884  O OE2 . GLU A 1 114 ? 10.08294  21.47530  -17.23002 1.000 33.60539 ? 114 GLU A OE2 1 
ATOM   885  N N   . TYR A 1 115 ? 11.52488  27.23158  -13.78953 1.000 27.46558 ? 115 TYR A N   1 
ATOM   886  C CA  . TYR A 1 115 ? 12.34336  28.24516  -13.13506 1.000 24.08283 ? 115 TYR A CA  1 
ATOM   887  C C   . TYR A 1 115 ? 12.21697  29.60914  -13.81024 1.000 28.39429 ? 115 TYR A C   1 
ATOM   888  O O   . TYR A 1 115 ? 13.18907  30.36069  -13.88289 1.000 33.64485 ? 115 TYR A O   1 
ATOM   889  C CB  . TYR A 1 115 ? 13.81190  27.84059  -13.13198 1.000 26.41775 ? 115 TYR A CB  1 
ATOM   890  C CG  . TYR A 1 115 ? 14.13884  26.56046  -12.42736 1.000 29.71731 ? 115 TYR A CG  1 
ATOM   891  C CD1 . TYR A 1 115 ? 13.90511  25.32528  -13.01756 1.000 28.91051 ? 115 TYR A CD1 1 
ATOM   892  C CD2 . TYR A 1 115 ? 14.73047  26.58568  -11.18180 1.000 33.20535 ? 115 TYR A CD2 1 
ATOM   893  C CE1 . TYR A 1 115 ? 14.24580  24.14567  -12.35851 1.000 25.19700 ? 115 TYR A CE1 1 
ATOM   894  C CE2 . TYR A 1 115 ? 15.06562  25.42636  -10.52290 1.000 34.74532 ? 115 TYR A CE2 1 
ATOM   895  C CZ  . TYR A 1 115 ? 14.82544  24.20841  -11.11111 1.000 29.30584 ? 115 TYR A CZ  1 
ATOM   896  O OH  . TYR A 1 115 ? 15.16626  23.06371  -10.43436 1.000 26.72478 ? 115 TYR A OH  1 
ATOM   897  N N   . GLY A 1 116 ? 11.04818  29.93341  -14.35511 1.000 27.55721 ? 116 GLY A N   1 
ATOM   898  C CA  . GLY A 1 116 ? 10.89191  31.23548  -14.97607 1.000 27.34801 ? 116 GLY A CA  1 
ATOM   899  C C   . GLY A 1 116 ? 11.62986  31.42595  -16.28506 1.000 27.41795 ? 116 GLY A C   1 
ATOM   900  O O   . GLY A 1 116 ? 11.60994  32.53176  -16.83869 1.000 22.65483 ? 116 GLY A O   1 
ATOM   901  N N   . ARG A 1 117 ? 12.28093  30.38701  -16.80655 1.000 26.55543 ? 117 ARG A N   1 
ATOM   902  C CA  . ARG A 1 117 ? 12.95816  30.46128  -18.09185 1.000 25.17616 ? 117 ARG A CA  1 
ATOM   903  C C   . ARG A 1 117 ? 12.26720  29.57508  -19.12957 1.000 25.51148 ? 117 ARG A C   1 
ATOM   904  O O   . ARG A 1 117 ? 11.59404  28.59085  -18.79164 1.000 24.10792 ? 117 ARG A O   1 
ATOM   905  C CB  . ARG A 1 117 ? 14.43029  30.07949  -17.94225 1.000 24.60617 ? 117 ARG A CB  1 
ATOM   906  C CG  . ARG A 1 117 ? 15.21295  31.02599  -17.03983 1.000 33.65920 ? 117 ARG A CG  1 
ATOM   907  C CD  . ARG A 1 117 ? 15.31885  32.43689  -17.63316 1.000 33.10910 ? 117 ARG A CD  1 
ATOM   908  N NE  . ARG A 1 117 ? 16.66824  32.72520  -18.11117 1.000 43.88027 ? 117 ARG A NE  1 
ATOM   909  C CZ  . ARG A 1 117 ? 17.47456  33.65261  -17.60825 1.000 45.61174 ? 117 ARG A CZ  1 
ATOM   910  N NH1 . ARG A 1 117 ? 17.09274  34.44102  -16.61429 1.000 37.93707 ? 117 ARG A NH1 1 
ATOM   911  N NH2 . ARG A 1 117 ? 18.69193  33.80158  -18.12679 1.000 44.90365 ? 117 ARG A NH2 1 
ATOM   912  N N   . PHE A 1 118 ? 12.42478  29.94691  -20.40325 1.000 22.31229 ? 118 PHE A N   1 
ATOM   913  C CA  . PHE A 1 118 ? 11.86775  29.14691  -21.49080 1.000 21.17234 ? 118 PHE A CA  1 
ATOM   914  C C   . PHE A 1 118 ? 12.74039  27.93098  -21.73770 1.000 24.53315 ? 118 PHE A C   1 
ATOM   915  O O   . PHE A 1 118 ? 13.95777  28.04460  -21.91807 1.000 23.01692 ? 118 PHE A O   1 
ATOM   916  C CB  . PHE A 1 118 ? 11.71698  29.96482  -22.77987 1.000 18.98099 ? 118 PHE A CB  1 
ATOM   917  C CG  . PHE A 1 118 ? 10.44601  30.75645  -22.82541 1.000 24.54974 ? 118 PHE A CG  1 
ATOM   918  C CD1 . PHE A 1 118 ? 9.25391   30.15209  -23.21677 1.000 24.71138 ? 118 PHE A CD1 1 
ATOM   919  C CD2 . PHE A 1 118 ? 10.41816  32.08509  -22.42061 1.000 19.84655 ? 118 PHE A CD2 1 
ATOM   920  C CE1 . PHE A 1 118 ? 8.06100   30.86738  -23.22913 1.000 14.92998 ? 118 PHE A CE1 1 
ATOM   921  C CE2 . PHE A 1 118 ? 9.23268   32.79807  -22.42049 1.000 20.08673 ? 118 PHE A CE2 1 
ATOM   922  C CZ  . PHE A 1 118 ? 8.04999   32.17953  -22.83449 1.000 20.02785 ? 118 PHE A CZ  1 
ATOM   923  N N   . LEU A 1 119 ? 12.11398  26.76159  -21.71176 1.000 23.00924 ? 119 LEU A N   1 
ATOM   924  C CA  . LEU A 1 119 ? 12.84543  25.54039  -21.95461 1.000 24.65334 ? 119 LEU A CA  1 
ATOM   925  C C   . LEU A 1 119 ? 13.42490  25.57287  -23.36178 1.000 29.84290 ? 119 LEU A C   1 
ATOM   926  O O   . LEU A 1 119 ? 12.85954  26.20247  -24.26429 1.000 26.53924 ? 119 LEU A O   1 
ATOM   927  C CB  . LEU A 1 119 ? 11.94523  24.31478  -21.79370 1.000 23.94283 ? 119 LEU A CB  1 
ATOM   928  C CG  . LEU A 1 119 ? 11.49835  24.05247  -20.36253 1.000 25.14813 ? 119 LEU A CG  1 
ATOM   929  C CD1 . LEU A 1 119 ? 11.29235  22.57327  -20.14741 1.000 21.85708 ? 119 LEU A CD1 1 
ATOM   930  C CD2 . LEU A 1 119 ? 12.50557  24.62788  -19.36293 1.000 26.79259 ? 119 LEU A CD2 1 
ATOM   931  N N   . PRO A 1 120 ? 14.56325  24.92749  -23.56245 1.000 32.20220 ? 120 PRO A N   1 
ATOM   932  C CA  . PRO A 1 120 ? 15.09561  24.72353  -24.90915 1.000 32.99991 ? 120 PRO A CA  1 
ATOM   933  C C   . PRO A 1 120 ? 14.53422  23.44678  -25.52649 1.000 31.68448 ? 120 PRO A C   1 
ATOM   934  O O   . PRO A 1 120 ? 13.90696  22.62153  -24.86529 1.000 25.00848 ? 120 PRO A O   1 
ATOM   935  C CB  . PRO A 1 120 ? 16.60118  24.59167  -24.65814 1.000 31.08209 ? 120 PRO A CB  1 
ATOM   936  C CG  . PRO A 1 120 ? 16.71198  24.11140  -23.19499 1.000 39.40823 ? 120 PRO A CG  1 
ATOM   937  C CD  . PRO A 1 120 ? 15.38113  24.26779  -22.52831 1.000 26.82251 ? 120 PRO A CD  1 
ATOM   938  N N   . GLN A 1 121 ? 14.78378  23.29171  -26.80338 1.000 36.77920 ? 121 GLN A N   1 
ATOM   939  C CA  . GLN A 1 121 ? 14.46621  22.01134  -27.41933 1.000 36.65220 ? 121 GLN A CA  1 
ATOM   940  C C   . GLN A 1 121 ? 15.26044  20.90304  -26.73119 1.000 39.25977 ? 121 GLN A C   1 
ATOM   941  O O   . GLN A 1 121 ? 16.19593  21.19047  -25.97302 1.000 37.15023 ? 121 GLN A O   1 
ATOM   942  C CB  . GLN A 1 121 ? 14.78603  22.04714  -28.91472 1.000 34.72249 ? 121 GLN A CB  1 
ATOM   943  C CG  . GLN A 1 121 ? 13.62831  21.60104  -29.79264 1.000 37.61499 ? 121 GLN A CG  1 
ATOM   944  C CD  . GLN A 1 121 ? 12.44691  22.54274  -29.72013 1.000 27.73253 ? 121 GLN A CD  1 
ATOM   945  O OE1 . GLN A 1 121 ? 12.58462  23.73225  -29.97496 1.000 32.10087 ? 121 GLN A OE1 1 
ATOM   946  N NE2 . GLN A 1 121 ? 11.27737  22.01522  -29.36506 1.000 33.98052 ? 121 GLN A NE2 1 
ATOM   947  N N   . PRO A 1 122 ? 14.94933  19.62645  -26.97762 1.000 36.47842 ? 122 PRO A N   1 
ATOM   948  C CA  . PRO A 1 122 ? 15.94331  18.57932  -26.69208 1.000 35.76300 ? 122 PRO A CA  1 
ATOM   949  C C   . PRO A 1 122 ? 17.24052  18.79295  -27.46062 1.000 42.00664 ? 122 PRO A C   1 
ATOM   950  O O   . PRO A 1 122 ? 18.11671  17.93256  -27.41144 1.000 47.51226 ? 122 PRO A O   1 
ATOM   951  C CB  . PRO A 1 122 ? 15.24298  17.28900  -27.14038 1.000 39.46592 ? 122 PRO A CB  1 
ATOM   952  C CG  . PRO A 1 122 ? 13.76904  17.58222  -27.00131 1.000 35.24520 ? 122 PRO A CG  1 
ATOM   953  C CD  . PRO A 1 122 ? 13.62498  19.06973  -27.31754 1.000 32.61151 ? 122 PRO A CD  1 
ATOM   954  N N   . GLY A 1 123 ? 17.36515  19.92276  -28.17440 1.000 50.32342 ? 123 GLY A N   1 
ATOM   955  C CA  . GLY A 1 123 ? 18.47355  20.24423  -29.05907 1.000 40.04091 ? 123 GLY A CA  1 
ATOM   956  C C   . GLY A 1 123 ? 19.49430  21.26874  -28.58247 1.000 46.02753 ? 123 GLY A C   1 
ATOM   957  O O   . GLY A 1 123 ? 20.48756  21.49808  -29.28200 1.000 49.90031 ? 123 GLY A O   1 
ATOM   958  N N   . HIS A 1 124 ? 19.28505  21.90401  -27.42269 1.000 46.24097 ? 124 HIS A N   1 
ATOM   959  C CA  . HIS A 1 124 ? 20.36304  22.65092  -26.75056 1.000 49.66439 ? 124 HIS A CA  1 
ATOM   960  C C   . HIS A 1 124 ? 20.22024  22.51255  -25.22793 1.000 46.00040 ? 124 HIS A C   1 
ATOM   961  O O   . HIS A 1 124 ? 20.05063  23.46657  -24.48233 1.000 47.56597 ? 124 HIS A O   1 
ATOM   962  C CB  . HIS A 1 124 ? 20.46805  24.12182  -27.19428 1.000 53.69627 ? 124 HIS A CB  1 
ATOM   963  C CG  . HIS A 1 124 ? 19.17084  24.88199  -27.27050 1.000 48.84671 ? 124 HIS A CG  1 
ATOM   964  N ND1 . HIS A 1 124 ? 18.06017  24.42357  -27.94949 1.000 49.65093 ? 124 HIS A ND1 1 
ATOM   965  C CD2 . HIS A 1 124 ? 18.84643  26.12053  -26.82158 1.000 48.69429 ? 124 HIS A CD2 1 
ATOM   966  C CE1 . HIS A 1 124 ? 17.09748  25.32786  -27.88025 1.000 41.00120 ? 124 HIS A CE1 1 
ATOM   967  N NE2 . HIS A 1 124 ? 17.54882  26.36718  -27.20106 1.000 43.98665 ? 124 HIS A NE2 1 
ATOM   968  N N   . GLU A 1 125 ? 20.36406  21.27759  -24.75915 1.000 46.55447 ? 125 GLU A N   1 
ATOM   969  C CA  . GLU A 1 125 ? 20.15807  20.93000  -23.35610 1.000 40.44132 ? 125 GLU A CA  1 
ATOM   970  C C   . GLU A 1 125 ? 21.32439  21.37599  -22.48135 1.000 43.81970 ? 125 GLU A C   1 
ATOM   971  O O   . GLU A 1 125 ? 21.12184  21.81424  -21.34407 1.000 43.59258 ? 125 GLU A O   1 
ATOM   972  C CB  . GLU A 1 125 ? 19.94903  19.42042  -23.24613 1.000 37.35806 ? 125 GLU A CB  1 
ATOM   973  C CG  . GLU A 1 125 ? 21.03961  18.56138  -23.94793 1.000 46.98129 ? 125 GLU A CG  1 
ATOM   974  C CD  . GLU A 1 125 ? 21.03737  18.68802  -25.49242 1.000 53.06650 ? 125 GLU A CD  1 
ATOM   975  O OE1 . GLU A 1 125 ? 22.08368  18.55570  -26.14363 1.000 53.50693 ? 125 GLU A OE1 1 
ATOM   976  O OE2 . GLU A 1 125 ? 19.96372  18.95814  -26.04774 1.000 64.02391 ? 125 GLU A OE2 1 
ATOM   977  N N   . GLY A 1 126 ? 22.54951  21.27453  -22.98827 1.000 47.58913 ? 126 GLY A N   1 
ATOM   978  C CA  . GLY A 1 126 ? 23.72121  21.59659  -22.19606 1.000 41.40324 ? 126 GLY A CA  1 
ATOM   979  C C   . GLY A 1 126 ? 24.22664  23.01728  -22.34623 1.000 38.92771 ? 126 GLY A C   1 
ATOM   980  O O   . GLY A 1 126 ? 24.65398  23.64188  -21.36607 1.000 41.12563 ? 126 GLY A O   1 
ATOM   981  N N   . GLU A 1 127 ? 24.21444  23.53615  -23.57403 1.000 37.52975 ? 127 GLU A N   1 
ATOM   982  C CA  . GLU A 1 127 ? 24.58957  24.92862  -23.76867 1.000 37.55528 ? 127 GLU A CA  1 
ATOM   983  C C   . GLU A 1 127 ? 23.53736  25.87620  -23.22028 1.000 41.41641 ? 127 GLU A C   1 
ATOM   984  O O   . GLU A 1 127 ? 23.81435  27.07061  -23.06645 1.000 40.40663 ? 127 GLU A O   1 
ATOM   985  C CB  . GLU A 1 127 ? 24.83897  25.22514  -25.25034 1.000 41.61003 ? 127 GLU A CB  1 
ATOM   986  C CG  . GLU A 1 127 ? 26.33051  25.33363  -25.64374 1.000 49.03444 ? 127 GLU A CG  1 
ATOM   987  C CD  . GLU A 1 127 ? 26.98896  26.68619  -25.29591 1.000 53.97024 ? 127 GLU A CD  1 
ATOM   988  O OE1 . GLU A 1 127 ? 27.94029  27.08552  -26.00497 1.000 57.30303 ? 127 GLU A OE1 1 
ATOM   989  O OE2 . GLU A 1 127 ? 26.57102  27.35093  -24.31835 1.000 46.78743 ? 127 GLU A OE2 1 
ATOM   990  N N   . TRP A 1 128 ? 22.34351  25.37231  -22.92005 1.000 36.89029 ? 128 TRP A N   1 
ATOM   991  C CA  . TRP A 1 128 ? 21.31259  26.22016  -22.33881 1.000 37.27804 ? 128 TRP A CA  1 
ATOM   992  C C   . TRP A 1 128 ? 21.63820  26.53517  -20.88670 1.000 38.72493 ? 128 TRP A C   1 
ATOM   993  O O   . TRP A 1 128 ? 21.68111  27.70644  -20.48287 1.000 34.91589 ? 128 TRP A O   1 
ATOM   994  C CB  . TRP A 1 128 ? 19.95734  25.53590  -22.46376 1.000 31.56838 ? 128 TRP A CB  1 
ATOM   995  C CG  . TRP A 1 128 ? 18.84318  26.24677  -21.83877 1.000 27.97685 ? 128 TRP A CG  1 
ATOM   996  C CD1 . TRP A 1 128 ? 18.06436  27.20819  -22.40343 1.000 29.89118 ? 128 TRP A CD1 1 
ATOM   997  C CD2 . TRP A 1 128 ? 18.33692  26.03897  -20.51992 1.000 31.55567 ? 128 TRP A CD2 1 
ATOM   998  N NE1 . TRP A 1 128 ? 17.10681  27.62397  -21.51195 1.000 30.24883 ? 128 TRP A NE1 1 
ATOM   999  C CE2 . TRP A 1 128 ? 17.25719  26.92508  -20.34409 1.000 26.28581 ? 128 TRP A CE2 1 
ATOM   1000 C CE3 . TRP A 1 128 ? 18.70110  25.19927  -19.46292 1.000 28.13245 ? 128 TRP A CE3 1 
ATOM   1001 C CZ2 . TRP A 1 128 ? 16.53723  26.99136  -19.16118 1.000 27.79462 ? 128 TRP A CZ2 1 
ATOM   1002 C CZ3 . TRP A 1 128 ? 17.98762  25.26952  -18.29201 1.000 28.41891 ? 128 TRP A CZ3 1 
ATOM   1003 C CH2 . TRP A 1 128 ? 16.91769  26.15654  -18.14684 1.000 32.91551 ? 128 TRP A CH2 1 
ATOM   1004 N N   . PHE A 1 129 ? 21.88684  25.49456  -20.09361 1.000 34.51307 ? 129 PHE A N   1 
ATOM   1005 C CA  . PHE A 1 129 ? 22.32995  25.69171  -18.72262 1.000 36.85285 ? 129 PHE A CA  1 
ATOM   1006 C C   . PHE A 1 129 ? 23.55385  26.60296  -18.65203 1.000 33.55264 ? 129 PHE A C   1 
ATOM   1007 O O   . PHE A 1 129 ? 23.68354  27.38712  -17.70754 1.000 33.11974 ? 129 PHE A O   1 
ATOM   1008 C CB  . PHE A 1 129 ? 22.59989  24.32703  -18.08577 1.000 37.61376 ? 129 PHE A CB  1 
ATOM   1009 C CG  . PHE A 1 129 ? 23.15220  24.39924  -16.70565 1.000 37.62433 ? 129 PHE A CG  1 
ATOM   1010 C CD1 . PHE A 1 129 ? 22.32720  24.67181  -15.63182 1.000 37.42000 ? 129 PHE A CD1 1 
ATOM   1011 C CD2 . PHE A 1 129 ? 24.49313  24.18339  -16.47870 1.000 38.41661 ? 129 PHE A CD2 1 
ATOM   1012 C CE1 . PHE A 1 129 ? 22.82985  24.73156  -14.35394 1.000 40.37484 ? 129 PHE A CE1 1 
ATOM   1013 C CE2 . PHE A 1 129 ? 25.00326  24.24822  -15.20145 1.000 44.91196 ? 129 PHE A CE2 1 
ATOM   1014 C CZ  . PHE A 1 129 ? 24.16502  24.51825  -14.13703 1.000 38.82535 ? 129 PHE A CZ  1 
ATOM   1015 N N   . ASP A 1 130 ? 24.42306  26.56531  -19.66879 1.000 35.02340 ? 130 ASP A N   1 
ATOM   1016 C CA  . ASP A 1 130 ? 25.61413  27.41358  -19.69763 1.000 38.84828 ? 130 ASP A CA  1 
ATOM   1017 C C   . ASP A 1 130 ? 25.32437  28.88587  -19.98900 1.000 42.26223 ? 130 ASP A C   1 
ATOM   1018 O O   . ASP A 1 130 ? 26.27796  29.66920  -20.06367 1.000 37.11470 ? 130 ASP A O   1 
ATOM   1019 C CB  . ASP A 1 130 ? 26.61577  26.89123  -20.72490 1.000 39.20286 ? 130 ASP A CB  1 
ATOM   1020 C CG  . ASP A 1 130 ? 27.44491  25.74519  -20.19483 1.000 44.55775 ? 130 ASP A CG  1 
ATOM   1021 O OD1 . ASP A 1 130 ? 26.85617  24.79239  -19.64176 1.000 45.68193 ? 130 ASP A OD1 1 
ATOM   1022 O OD2 . ASP A 1 130 ? 28.68432  25.78603  -20.33702 1.000 52.72686 ? 130 ASP A OD2 1 
ATOM   1023 N N   . ASN A 1 131 ? 24.06639  29.30365  -20.16110 1.000 39.22327 ? 131 ASN A N   1 
ATOM   1024 C CA  . ASN A 1 131 ? 23.78467  30.73237  -20.23851 1.000 33.65748 ? 131 ASN A CA  1 
ATOM   1025 C C   . ASN A 1 131 ? 22.70333  31.18751  -19.25963 1.000 40.71925 ? 131 ASN A C   1 
ATOM   1026 O O   . ASN A 1 131 ? 22.06977  32.22286  -19.49069 1.000 47.99714 ? 131 ASN A O   1 
ATOM   1027 C CB  . ASN A 1 131 ? 23.41571  31.14724  -21.66666 1.000 35.66112 ? 131 ASN A CB  1 
ATOM   1028 C CG  . ASN A 1 131 ? 24.23312  32.33855  -22.14448 1.000 28.51319 ? 131 ASN A CG  1 
ATOM   1029 O OD1 . ASN A 1 131 ? 24.02516  33.46392  -21.70687 1.000 31.58495 ? 131 ASN A OD1 1 
ATOM   1030 N ND2 . ASN A 1 131 ? 25.18436  32.08680  -23.01862 1.000 36.28989 ? 131 ASN A ND2 1 
ATOM   1031 N N   . LEU A 1 132 ? 22.46266  30.45331  -18.17548 1.000 35.75487 ? 132 LEU A N   1 
ATOM   1032 C CA  . LEU A 1 132 ? 21.67354  31.04085  -17.10593 1.000 34.48371 ? 132 LEU A CA  1 
ATOM   1033 C C   . LEU A 1 132 ? 22.56892  31.96456  -16.29525 1.000 35.98610 ? 132 LEU A C   1 
ATOM   1034 O O   . LEU A 1 132 ? 23.78704  31.95507  -16.44324 1.000 38.37171 ? 132 LEU A O   1 
ATOM   1035 C CB  . LEU A 1 132 ? 21.07210  29.96124  -16.21177 1.000 41.44581 ? 132 LEU A CB  1 
ATOM   1036 C CG  . LEU A 1 132 ? 20.00761  29.03027  -16.80662 1.000 43.30254 ? 132 LEU A CG  1 
ATOM   1037 C CD1 . LEU A 1 132 ? 20.35521  27.58839  -16.49895 1.000 39.09165 ? 132 LEU A CD1 1 
ATOM   1038 C CD2 . LEU A 1 132 ? 18.62964  29.36851  -16.24794 1.000 44.52111 ? 132 LEU A CD2 1 
ATOM   1039 N N   . SER A 1 133 ? 21.97737  32.77560  -15.42935 1.000 34.35600 ? 133 SER A N   1 
ATOM   1040 C CA  . SER A 1 133 ? 22.81105  33.55147  -14.52456 1.000 34.39962 ? 133 SER A CA  1 
ATOM   1041 C C   . SER A 1 133 ? 23.28369  32.65494  -13.38281 1.000 34.65182 ? 133 SER A C   1 
ATOM   1042 O O   . SER A 1 133 ? 22.53524  31.81512  -12.88209 1.000 32.28675 ? 133 SER A O   1 
ATOM   1043 C CB  . SER A 1 133 ? 22.07201  34.78871  -13.99488 1.000 32.57253 ? 133 SER A CB  1 
ATOM   1044 O OG  . SER A 1 133 ? 21.10962  34.48498  -13.01303 1.000 29.70064 ? 133 SER A OG  1 
ATOM   1045 N N   . SER A 1 134 ? 24.55720  32.81241  -13.01575 1.000 36.14295 ? 134 SER A N   1 
ATOM   1046 C CA  . SER A 1 134 ? 25.19132  32.02554  -11.95858 1.000 34.71774 ? 134 SER A CA  1 
ATOM   1047 C C   . SER A 1 134 ? 24.27099  31.72104  -10.77665 1.000 33.09187 ? 134 SER A C   1 
ATOM   1048 O O   . SER A 1 134 ? 24.21194  30.58127  -10.31328 1.000 27.09749 ? 134 SER A O   1 
ATOM   1049 C CB  . SER A 1 134 ? 26.44308  32.76226  -11.47479 1.000 31.53022 ? 134 SER A CB  1 
ATOM   1050 O OG  . SER A 1 134 ? 27.36464  32.95183  -12.53220 1.000 44.89896 ? 134 SER A OG  1 
ATOM   1051 N N   . ASP A 1 135 ? 23.55676  32.73664  -10.26777 1.000 34.48537 ? 135 ASP A N   1 
ATOM   1052 C CA  . ASP A 1 135 ? 22.63513  32.53082  -9.14892  1.000 39.59756 ? 135 ASP A CA  1 
ATOM   1053 C C   . ASP A 1 135 ? 21.50107  31.58342  -9.51111  1.000 35.37486 ? 135 ASP A C   1 
ATOM   1054 O O   . ASP A 1 135 ? 21.01978  30.83794  -8.65580  1.000 35.47417 ? 135 ASP A O   1 
ATOM   1055 C CB  . ASP A 1 135 ? 22.05536  33.86631  -8.67839  1.000 38.36411 ? 135 ASP A CB  1 
ATOM   1056 C CG  . ASP A 1 135 ? 23.08335  34.73007  -7.96378  1.000 49.22555 ? 135 ASP A CG  1 
ATOM   1057 O OD1 . ASP A 1 135 ? 24.03749  34.16699  -7.38403  1.000 48.84799 ? 135 ASP A OD1 1 
ATOM   1058 O OD2 . ASP A 1 135 ? 22.93813  35.97292  -7.98182  1.000 58.10948 ? 135 ASP A OD2 1 
ATOM   1059 N N   . GLU A 1 136 ? 21.04381  31.62249  -10.76103 1.000 37.38826 ? 136 GLU A N   1 
ATOM   1060 C CA  . GLU A 1 136 ? 20.09070  30.63297  -11.24638 1.000 34.39302 ? 136 GLU A CA  1 
ATOM   1061 C C   . GLU A 1 136 ? 20.73153  29.25844  -11.35507 1.000 34.32463 ? 136 GLU A C   1 
ATOM   1062 O O   . GLU A 1 136 ? 20.09597  28.25156  -11.02718 1.000 33.57217 ? 136 GLU A O   1 
ATOM   1063 C CB  . GLU A 1 136 ? 19.52373  31.07139  -12.59547 1.000 31.75111 ? 136 GLU A CB  1 
ATOM   1064 C CG  . GLU A 1 136 ? 18.82758  32.42665  -12.52584 1.000 36.30055 ? 136 GLU A CG  1 
ATOM   1065 C CD  . GLU A 1 136 ? 18.39427  32.95364  -13.88408 1.000 39.16169 ? 136 GLU A CD  1 
ATOM   1066 O OE1 . GLU A 1 136 ? 17.80815  32.18734  -14.66936 1.000 36.37759 ? 136 GLU A OE1 1 
ATOM   1067 O OE2 . GLU A 1 136 ? 18.63520  34.14103  -14.16307 1.000 38.24158 ? 136 GLU A OE2 1 
ATOM   1068 N N   . ARG A 1 137 ? 21.98390  29.18743  -11.81939 1.000 31.18320 ? 137 ARG A N   1 
ATOM   1069 C CA  . ARG A 1 137 ? 22.68633  27.90384  -11.83205 1.000 33.03304 ? 137 ARG A CA  1 
ATOM   1070 C C   . ARG A 1 137 ? 22.87916  27.36737  -10.41540 1.000 39.14234 ? 137 ARG A C   1 
ATOM   1071 O O   . ARG A 1 137 ? 22.64821  26.18478  -10.15000 1.000 44.01872 ? 137 ARG A O   1 
ATOM   1072 C CB  . ARG A 1 137 ? 24.03620  28.03604  -12.53740 1.000 41.01456 ? 137 ARG A CB  1 
ATOM   1073 C CG  . ARG A 1 137 ? 23.95641  28.12889  -14.06045 1.000 36.69034 ? 137 ARG A CG  1 
ATOM   1074 C CD  . ARG A 1 137 ? 25.32517  27.95452  -14.68819 1.000 36.60826 ? 137 ARG A CD  1 
ATOM   1075 N NE  . ARG A 1 137 ? 26.25318  29.01885  -14.31820 1.000 43.19490 ? 137 ARG A NE  1 
ATOM   1076 C CZ  . ARG A 1 137 ? 27.53048  29.05941  -14.67577 1.000 52.73974 ? 137 ARG A CZ  1 
ATOM   1077 N NH1 . ARG A 1 137 ? 28.07577  28.09348  -15.39727 1.000 55.27998 ? 137 ARG A NH1 1 
ATOM   1078 N NH2 . ARG A 1 137 ? 28.27854  30.09847  -14.30558 1.000 50.77200 ? 137 ARG A NH2 1 
ATOM   1079 N N   . ALA A 1 138 ? 23.30845  28.22669  -9.49054  1.000 35.50693 ? 138 ALA A N   1 
ATOM   1080 C CA  . ALA A 1 138 ? 23.48244  27.80561  -8.10629  1.000 42.63769 ? 138 ALA A CA  1 
ATOM   1081 C C   . ALA A 1 138 ? 22.16396  27.32708  -7.50953  1.000 37.09821 ? 138 ALA A C   1 
ATOM   1082 O O   . ALA A 1 138 ? 22.13960  26.38601  -6.70867  1.000 36.66938 ? 138 ALA A O   1 
ATOM   1083 C CB  . ALA A 1 138 ? 24.06714  28.95838  -7.28302  1.000 41.43624 ? 138 ALA A CB  1 
ATOM   1084 N N   . PHE A 1 139 ? 21.06153  27.97872  -7.88080  1.000 29.48285 ? 139 PHE A N   1 
ATOM   1085 C CA  . PHE A 1 139 ? 19.73632  27.50056  -7.50758  1.000 35.35628 ? 139 PHE A CA  1 
ATOM   1086 C C   . PHE A 1 139 ? 19.45862  26.12253  -8.10033  1.000 35.46438 ? 139 PHE A C   1 
ATOM   1087 O O   . PHE A 1 139 ? 18.89747  25.25150  -7.42802  1.000 41.45355 ? 139 PHE A O   1 
ATOM   1088 C CB  . PHE A 1 139 ? 18.69586  28.50757  -7.97927  1.000 37.44693 ? 139 PHE A CB  1 
ATOM   1089 C CG  . PHE A 1 139 ? 17.35884  28.34984  -7.34747  1.000 26.49165 ? 139 PHE A CG  1 
ATOM   1090 C CD1 . PHE A 1 139 ? 17.22999  28.34480  -5.97848  1.000 26.55197 ? 139 PHE A CD1 1 
ATOM   1091 C CD2 . PHE A 1 139 ? 16.21907  28.26286  -8.13097  1.000 25.10306 ? 139 PHE A CD2 1 
ATOM   1092 C CE1 . PHE A 1 139 ? 15.99004  28.22801  -5.38666  1.000 29.10279 ? 139 PHE A CE1 1 
ATOM   1093 C CE2 . PHE A 1 139 ? 14.97857  28.15734  -7.55531  1.000 28.68573 ? 139 PHE A CE2 1 
ATOM   1094 C CZ  . PHE A 1 139 ? 14.86292  28.13303  -6.17798  1.000 31.30637 ? 139 PHE A CZ  1 
ATOM   1095 N N   . MET A 1 140 ? 19.85678  25.91117  -9.35764  1.000 36.92041 ? 140 MET A N   1 
ATOM   1096 C CA  . MET A 1 140 ? 19.65865  24.63104  -10.03161 1.000 37.17543 ? 140 MET A CA  1 
ATOM   1097 C C   . MET A 1 140 ? 20.26116  23.48222  -9.24560  1.000 39.77778 ? 140 MET A C   1 
ATOM   1098 O O   . MET A 1 140 ? 19.69890  22.38236  -9.19734  1.000 39.24926 ? 140 MET A O   1 
ATOM   1099 C CB  . MET A 1 140 ? 20.29174  24.67400  -11.42385 1.000 38.01763 ? 140 MET A CB  1 
ATOM   1100 C CG  . MET A 1 140 ? 19.34300  24.40507  -12.53638 1.000 37.30624 ? 140 MET A CG  1 
ATOM   1101 S SD  . MET A 1 140 ? 17.91312  25.50299  -12.51708 1.000 46.99200 ? 140 MET A SD  1 
ATOM   1102 C CE  . MET A 1 140 ? 18.59878  26.87755  -13.44225 1.000 32.46765 ? 140 MET A CE  1 
ATOM   1103 N N   . GLU A 1 141 ? 21.40328  23.72557  -8.61294  1.000 43.89798 ? 141 GLU A N   1 
ATOM   1104 C CA  . GLU A 1 141 ? 22.22661  22.63491  -8.12065  1.000 40.93604 ? 141 GLU A CA  1 
ATOM   1105 C C   . GLU A 1 141 ? 21.69305  22.02133  -6.83897  1.000 36.21565 ? 141 GLU A C   1 
ATOM   1106 O O   . GLU A 1 141 ? 21.97691  20.85097  -6.56955  1.000 40.00640 ? 141 GLU A O   1 
ATOM   1107 C CB  . GLU A 1 141 ? 23.64837  23.12669  -7.89835  1.000 50.36215 ? 141 GLU A CB  1 
ATOM   1108 C CG  . GLU A 1 141 ? 24.40117  23.45027  -9.15921  1.000 46.38117 ? 141 GLU A CG  1 
ATOM   1109 C CD  . GLU A 1 141 ? 25.78958  23.92823  -8.83356  1.000 53.31419 ? 141 GLU A CD  1 
ATOM   1110 O OE1 . GLU A 1 141 ? 25.96338  24.47044  -7.71553  1.000 47.61329 ? 141 GLU A OE1 1 
ATOM   1111 O OE2 . GLU A 1 141 ? 26.70041  23.74225  -9.67035  1.000 53.39491 ? 141 GLU A OE2 1 
ATOM   1112 N N   . THR A 1 142 ? 20.94967  22.77861  -6.02603  1.000 31.35375 ? 142 THR A N   1 
ATOM   1113 C CA  . THR A 1 142 ? 20.38085  22.18618  -4.81666  1.000 32.25849 ? 142 THR A CA  1 
ATOM   1114 C C   . THR A 1 142 ? 19.38848  21.07205  -5.12094  1.000 34.84437 ? 142 THR A C   1 
ATOM   1115 O O   . THR A 1 142 ? 19.04365  20.31051  -4.21509  1.000 37.61254 ? 142 THR A O   1 
ATOM   1116 C CB  . THR A 1 142 ? 19.66319  23.23207  -3.95890  1.000 35.23869 ? 142 THR A CB  1 
ATOM   1117 O OG1 . THR A 1 142 ? 18.88136  24.08404  -4.79983  1.000 36.94310 ? 142 THR A OG1 1 
ATOM   1118 C CG2 . THR A 1 142 ? 20.64790  24.05805  -3.14466  1.000 41.72116 ? 142 THR A CG2 1 
ATOM   1119 N N   . ASN A 1 143 ? 18.91801  20.96663  -6.36238  1.000 40.94187 ? 143 ASN A N   1 
ATOM   1120 C CA  . ASN A 1 143 ? 17.91418  19.97902  -6.73415  1.000 36.99132 ? 143 ASN A CA  1 
ATOM   1121 C C   . ASN A 1 143 ? 18.54429  18.88724  -7.58901  1.000 34.43795 ? 143 ASN A C   1 
ATOM   1122 O O   . ASN A 1 143 ? 18.12899  18.62036  -8.71781  1.000 31.43521 ? 143 ASN A O   1 
ATOM   1123 C CB  . ASN A 1 143 ? 16.75842  20.68041  -7.42940  1.000 30.77625 ? 143 ASN A CB  1 
ATOM   1124 C CG  . ASN A 1 143 ? 16.32540  21.90687  -6.66744  1.000 34.06950 ? 143 ASN A CG  1 
ATOM   1125 O OD1 . ASN A 1 143 ? 16.35274  21.91231  -5.43436  1.000 32.44781 ? 143 ASN A OD1 1 
ATOM   1126 N ND2 . ASN A 1 143 ? 15.96926  22.96641  -7.38336  1.000 28.28224 ? 143 ASN A ND2 1 
ATOM   1127 N N   . VAL A 1 144 ? 19.58488  18.27846  -7.04543  1.000 36.30752 ? 144 VAL A N   1 
ATOM   1128 C CA  . VAL A 1 144 ? 20.13816  17.03373  -7.54397  1.000 34.89236 ? 144 VAL A CA  1 
ATOM   1129 C C   . VAL A 1 144 ? 20.11910  16.04104  -6.39174  1.000 37.70956 ? 144 VAL A C   1 
ATOM   1130 O O   . VAL A 1 144 ? 20.51283  16.38657  -5.26950  1.000 39.49534 ? 144 VAL A O   1 
ATOM   1131 C CB  . VAL A 1 144 ? 21.56134  17.22909  -8.08872  1.000 41.59043 ? 144 VAL A CB  1 
ATOM   1132 C CG1 . VAL A 1 144 ? 21.95546  16.05484  -8.97428  1.000 40.43463 ? 144 VAL A CG1 1 
ATOM   1133 C CG2 . VAL A 1 144 ? 21.64623  18.55493  -8.84300  1.000 38.67336 ? 144 VAL A CG2 1 
ATOM   1134 N N   . ASP A 1 145 ? 19.62480  14.82888  -6.66392  1.000 40.19382 ? 145 ASP A N   1 
ATOM   1135 C CA  . ASP A 1 145 ? 19.60658  13.72656  -5.69669  1.000 41.93288 ? 145 ASP A CA  1 
ATOM   1136 C C   . ASP A 1 145 ? 19.63042  12.36871  -6.41288  1.000 42.11319 ? 145 ASP A C   1 
ATOM   1137 O O   . ASP A 1 145 ? 20.65317  11.92558  -6.95883  1.000 47.84290 ? 145 ASP A O   1 
ATOM   1138 C CB  . ASP A 1 145 ? 18.35664  13.80714  -4.79985  1.000 45.69170 ? 145 ASP A CB  1 
ATOM   1139 C CG  . ASP A 1 145 ? 18.43988  12.89057  -3.57333  1.000 53.88386 ? 145 ASP A CG  1 
ATOM   1140 O OD1 . ASP A 1 145 ? 19.27279  11.95170  -3.56002  1.000 53.25854 ? 145 ASP A OD1 1 
ATOM   1141 O OD2 . ASP A 1 145 ? 17.66799  13.10703  -2.61400  1.000 45.37870 ? 145 ASP A OD2 1 
ATOM   1142 N N   . PRO B 1 1   ? -8.80919  5.88720   -21.49237 1.000 25.16396 ? 1   PRO B N   1 
ATOM   1143 C CA  . PRO B 1 1   ? -8.99404  7.30428   -21.16374 1.000 20.94526 ? 1   PRO B CA  1 
ATOM   1144 C C   . PRO B 1 1   ? -8.98374  7.60304   -19.67209 1.000 23.45948 ? 1   PRO B C   1 
ATOM   1145 O O   . PRO B 1 1   ? -9.52567  6.84774   -18.85300 1.000 21.06975 ? 1   PRO B O   1 
ATOM   1146 C CB  . PRO B 1 1   ? -10.37101 7.62007   -21.73810 1.000 23.20320 ? 1   PRO B CB  1 
ATOM   1147 C CG  . PRO B 1 1   ? -11.01029 6.28761   -22.02306 1.000 24.12351 ? 1   PRO B CG  1 
ATOM   1148 C CD  . PRO B 1 1   ? -10.08647 5.19262   -21.67719 1.000 19.54334 ? 1   PRO B CD  1 
ATOM   1149 N N   . VAL B 1 2   ? -8.37697  8.72398   -19.30410 1.000 21.71149 ? 2   VAL B N   1 
ATOM   1150 C CA  . VAL B 1 2   ? -8.46722  9.21553   -17.94086 1.000 16.60318 ? 2   VAL B CA  1 
ATOM   1151 C C   . VAL B 1 2   ? -9.28218  10.49115  -17.97955 1.000 17.59938 ? 2   VAL B C   1 
ATOM   1152 O O   . VAL B 1 2   ? -8.98490  11.41899  -18.74588 1.000 19.91392 ? 2   VAL B O   1 
ATOM   1153 C CB  . VAL B 1 2   ? -7.08320  9.42626   -17.30557 1.000 16.36134 ? 2   VAL B CB  1 
ATOM   1154 C CG1 . VAL B 1 2   ? -7.21785  10.05516  -15.94138 1.000 11.19548 ? 2   VAL B CG1 1 
ATOM   1155 C CG2 . VAL B 1 2   ? -6.33506  8.08851   -17.23236 1.000 15.19069 ? 2   VAL B CG2 1 
ATOM   1156 N N   . TYR B 1 3   ? -10.33682 10.51535  -17.19372 1.000 15.91431 ? 3   TYR B N   1 
ATOM   1157 C CA  . TYR B 1 3   ? -11.10887 11.71894  -16.98439 1.000 19.60721 ? 3   TYR B CA  1 
ATOM   1158 C C   . TYR B 1 3   ? -10.76167 12.26560  -15.61601 1.000 23.57637 ? 3   TYR B C   1 
ATOM   1159 O O   . TYR B 1 3   ? -11.03009 11.61749  -14.59385 1.000 24.96927 ? 3   TYR B O   1 
ATOM   1160 C CB  . TYR B 1 3   ? -12.59624 11.44002  -17.09971 1.000 18.62899 ? 3   TYR B CB  1 
ATOM   1161 C CG  . TYR B 1 3   ? -13.06211 11.23075  -18.50497 1.000 17.28434 ? 3   TYR B CG  1 
ATOM   1162 C CD1 . TYR B 1 3   ? -13.50207 12.30015  -19.27126 1.000 19.28590 ? 3   TYR B CD1 1 
ATOM   1163 C CD2 . TYR B 1 3   ? -13.09277 9.96022   -19.06776 1.000 21.05913 ? 3   TYR B CD2 1 
ATOM   1164 C CE1 . TYR B 1 3   ? -13.95512 12.11942  -20.55786 1.000 17.93575 ? 3   TYR B CE1 1 
ATOM   1165 C CE2 . TYR B 1 3   ? -13.55293 9.76431   -20.36925 1.000 17.42055 ? 3   TYR B CE2 1 
ATOM   1166 C CZ  . TYR B 1 3   ? -13.98268 10.85267  -21.09518 1.000 16.72613 ? 3   TYR B CZ  1 
ATOM   1167 O OH  . TYR B 1 3   ? -14.43491 10.69520  -22.36513 1.000 19.81943 ? 3   TYR B OH  1 
ATOM   1168 N N   . MET B 1 4   ? -10.13143 13.43324  -15.60789 1.000 19.55308 ? 4   MET B N   1 
ATOM   1169 C CA  . MET B 1 4   ? -9.92725  14.19482  -14.39431 1.000 16.07499 ? 4   MET B CA  1 
ATOM   1170 C C   . MET B 1 4   ? -11.14558 15.08557  -14.19504 1.000 22.41697 ? 4   MET B C   1 
ATOM   1171 O O   . MET B 1 4   ? -11.47209 15.91770  -15.05322 1.000 17.88872 ? 4   MET B O   1 
ATOM   1172 C CB  . MET B 1 4   ? -8.63662  14.99995  -14.47987 1.000 19.56880 ? 4   MET B CB  1 
ATOM   1173 C CG  . MET B 1 4   ? -7.40429  14.12210  -14.71424 1.000 24.24508 ? 4   MET B CG  1 
ATOM   1174 S SD  . MET B 1 4   ? -7.27521  12.57013  -13.76227 1.000 31.27687 ? 4   MET B SD  1 
ATOM   1175 C CE  . MET B 1 4   ? -5.96435  13.00443  -12.63694 1.000 28.39743 ? 4   MET B CE  1 
ATOM   1176 N N   . VAL B 1 5   ? -11.83429 14.88427  -13.07853 1.000 24.64882 ? 5   VAL B N   1 
ATOM   1177 C CA  . VAL B 1 5   ? -13.04223 15.62372  -12.74795 1.000 23.33795 ? 5   VAL B CA  1 
ATOM   1178 C C   . VAL B 1 5   ? -12.71529 16.51973  -11.56889 1.000 22.46474 ? 5   VAL B C   1 
ATOM   1179 O O   . VAL B 1 5   ? -12.47931 16.02979  -10.45754 1.000 28.52986 ? 5   VAL B O   1 
ATOM   1180 C CB  . VAL B 1 5   ? -14.20757 14.68749  -12.41323 1.000 20.24434 ? 5   VAL B CB  1 
ATOM   1181 C CG1 . VAL B 1 5   ? -15.42810 15.49850  -11.98348 1.000 19.17981 ? 5   VAL B CG1 1 
ATOM   1182 C CG2 . VAL B 1 5   ? -14.51520 13.79525  -13.58409 1.000 22.51144 ? 5   VAL B CG2 1 
ATOM   1183 N N   . TYR B 1 6   ? -12.73614 17.82742  -11.78789 1.000 25.97892 ? 6   TYR B N   1 
ATOM   1184 C CA  . TYR B 1 6   ? -12.41206 18.79347  -10.74448 1.000 25.03787 ? 6   TYR B CA  1 
ATOM   1185 C C   . TYR B 1 6   ? -13.69439 19.38599  -10.18927 1.000 27.83224 ? 6   TYR B C   1 
ATOM   1186 O O   . TYR B 1 6   ? -14.54738 19.85628  -10.94914 1.000 26.88342 ? 6   TYR B O   1 
ATOM   1187 C CB  . TYR B 1 6   ? -11.51149 19.90440  -11.27873 1.000 27.18078 ? 6   TYR B CB  1 
ATOM   1188 C CG  . TYR B 1 6   ? -10.23391 19.38830  -11.88292 1.000 21.23890 ? 6   TYR B CG  1 
ATOM   1189 C CD1 . TYR B 1 6   ? -9.07350  19.34168  -11.13726 1.000 22.31239 ? 6   TYR B CD1 1 
ATOM   1190 C CD2 . TYR B 1 6   ? -10.18952 18.95261  -13.20818 1.000 20.80636 ? 6   TYR B CD2 1 
ATOM   1191 C CE1 . TYR B 1 6   ? -7.89773  18.86400  -11.68189 1.000 29.29540 ? 6   TYR B CE1 1 
ATOM   1192 C CE2 . TYR B 1 6   ? -9.01340  18.46527  -13.76635 1.000 25.11258 ? 6   TYR B CE2 1 
ATOM   1193 C CZ  . TYR B 1 6   ? -7.87316  18.42236  -13.00079 1.000 22.43740 ? 6   TYR B CZ  1 
ATOM   1194 O OH  . TYR B 1 6   ? -6.69678  17.95374  -13.53247 1.000 26.30463 ? 6   TYR B OH  1 
ATOM   1195 N N   . VAL B 1 7   ? -13.80496 19.38101  -8.86333  1.000 29.18134 ? 7   VAL B N   1 
ATOM   1196 C CA  . VAL B 1 7   ? -15.03357 19.70450  -8.15722  1.000 26.10063 ? 7   VAL B CA  1 
ATOM   1197 C C   . VAL B 1 7   ? -14.66299 20.27910  -6.79230  1.000 35.01109 ? 7   VAL B C   1 
ATOM   1198 O O   . VAL B 1 7   ? -13.63069 19.93411  -6.20358  1.000 28.91419 ? 7   VAL B O   1 
ATOM   1199 C CB  . VAL B 1 7   ? -15.92825 18.45441  -8.01542  1.000 29.07564 ? 7   VAL B CB  1 
ATOM   1200 C CG1 . VAL B 1 7   ? -16.62507 18.13503  -9.33099  1.000 26.68988 ? 7   VAL B CG1 1 
ATOM   1201 C CG2 . VAL B 1 7   ? -15.08627 17.25893  -7.56056  1.000 32.67596 ? 7   VAL B CG2 1 
ATOM   1202 N N   . SER B 1 8   ? -15.50214 21.17578  -6.29116  1.000 28.99395 ? 8   SER B N   1 
ATOM   1203 C CA  . SER B 1 8   ? -15.28996 21.67509  -4.94503  1.000 32.29882 ? 8   SER B CA  1 
ATOM   1204 C C   . SER B 1 8   ? -15.70585 20.61901  -3.92177  1.000 37.54328 ? 8   SER B C   1 
ATOM   1205 O O   . SER B 1 8   ? -16.56753 19.77497  -4.18275  1.000 39.62621 ? 8   SER B O   1 
ATOM   1206 C CB  . SER B 1 8   ? -16.04265 22.98531  -4.74547  1.000 40.27877 ? 8   SER B CB  1 
ATOM   1207 O OG  . SER B 1 8   ? -15.47054 24.00801  -5.55779  1.000 31.93786 ? 8   SER B OG  1 
ATOM   1208 N N   . GLN B 1 9   ? -15.05138 20.65316  -2.76120  1.000 36.90224 ? 9   GLN B N   1 
ATOM   1209 C CA  . GLN B 1 9   ? -15.15164 19.57394  -1.78659  1.000 38.86844 ? 9   GLN B CA  1 
ATOM   1210 C C   . GLN B 1 9   ? -16.59459 19.39841  -1.30313  1.000 41.33842 ? 9   GLN B C   1 
ATOM   1211 O O   . GLN B 1 9   ? -17.37733 20.35238  -1.23793  1.000 41.35222 ? 9   GLN B O   1 
ATOM   1212 C CB  . GLN B 1 9   ? -14.20663 19.84925  -0.60781  1.000 36.33618 ? 9   GLN B CB  1 
ATOM   1213 C CG  . GLN B 1 9   ? -13.54459 18.61394  -0.00908  1.000 40.25558 ? 9   GLN B CG  1 
ATOM   1214 C CD  . GLN B 1 9   ? -12.07509 18.83660  0.39030   1.000 48.22625 ? 9   GLN B CD  1 
ATOM   1215 O OE1 . GLN B 1 9   ? -11.20304 19.00115  -0.46705  1.000 34.52782 ? 9   GLN B OE1 1 
ATOM   1216 N NE2 . GLN B 1 9   ? -11.80092 18.81843  1.69655   1.000 45.55780 ? 9   GLN B NE2 1 
ATOM   1217 N N   . ASP B 1 10  ? -16.95319 18.14644  -1.01102  1.000 32.47785 ? 10  ASP B N   1 
ATOM   1218 C CA  . ASP B 1 10  ? -18.25640 17.76002  -0.46230  1.000 41.87955 ? 10  ASP B CA  1 
ATOM   1219 C C   . ASP B 1 10  ? -19.44374 18.21118  -1.32475  1.000 41.13227 ? 10  ASP B C   1 
ATOM   1220 O O   . ASP B 1 10  ? -20.58674 18.23122  -0.85111  1.000 36.82416 ? 10  ASP B O   1 
ATOM   1221 C CB  . ASP B 1 10  ? -18.42616 18.27303  0.97601   1.000 38.60827 ? 10  ASP B CB  1 
ATOM   1222 C CG  . ASP B 1 10  ? -19.44656 17.46511  1.77136   1.000 49.15846 ? 10  ASP B CG  1 
ATOM   1223 O OD1 . ASP B 1 10  ? -19.10533 16.34679  2.19972   1.000 48.53386 ? 10  ASP B OD1 1 
ATOM   1224 O OD2 . ASP B 1 10  ? -20.58908 17.93652  1.97135   1.000 49.13255 ? 10  ASP B OD2 1 
ATOM   1225 N N   . ARG B 1 11  ? -19.22532 18.55924  -2.59472  1.000 41.51011 ? 11  ARG B N   1 
ATOM   1226 C CA  . ARG B 1 11  ? -20.36201 18.82157  -3.47531  1.000 39.72609 ? 11  ARG B CA  1 
ATOM   1227 C C   . ARG B 1 11  ? -21.03019 17.52576  -3.92292  1.000 40.35042 ? 11  ARG B C   1 
ATOM   1228 O O   . ARG B 1 11  ? -22.26080 17.40560  -3.88211  1.000 42.09687 ? 11  ARG B O   1 
ATOM   1229 C CB  . ARG B 1 11  ? -19.92334 19.64335  -4.68697  1.000 43.12608 ? 11  ARG B CB  1 
ATOM   1230 C CG  . ARG B 1 11  ? -20.92564 20.72448  -5.07745  1.000 44.89738 ? 11  ARG B CG  1 
ATOM   1231 C CD  . ARG B 1 11  ? -22.32953 20.16426  -5.11775  1.000 51.44763 ? 11  ARG B CD  1 
ATOM   1232 N NE  . ARG B 1 11  ? -23.32588 21.06078  -5.68902  1.000 52.04126 ? 11  ARG B NE  1 
ATOM   1233 C CZ  . ARG B 1 11  ? -24.62756 20.80570  -5.68366  1.000 53.71779 ? 11  ARG B CZ  1 
ATOM   1234 N NH1 . ARG B 1 11  ? -25.11321 19.71323  -5.11250  1.000 42.61751 ? 11  ARG B NH1 1 
ATOM   1235 N NH2 . ARG B 1 11  ? -25.45907 21.65126  -6.28863  1.000 60.28682 ? 11  ARG B NH2 1 
ATOM   1236 N N   . LEU B 1 12  ? -20.24390 16.55088  -4.36217  1.000 40.16008 ? 12  LEU B N   1 
ATOM   1237 C CA  . LEU B 1 12  ? -20.77817 15.24331  -4.71467  1.000 39.65097 ? 12  LEU B CA  1 
ATOM   1238 C C   . LEU B 1 12  ? -20.67076 14.33590  -3.49943  1.000 42.75919 ? 12  LEU B C   1 
ATOM   1239 O O   . LEU B 1 12  ? -19.57220 14.11391  -2.97333  1.000 45.69044 ? 12  LEU B O   1 
ATOM   1240 C CB  . LEU B 1 12  ? -20.04024 14.61959  -5.90120  1.000 38.90362 ? 12  LEU B CB  1 
ATOM   1241 C CG  . LEU B 1 12  ? -20.07378 15.20503  -7.31885  1.000 41.23799 ? 12  LEU B CG  1 
ATOM   1242 C CD1 . LEU B 1 12  ? -18.97043 14.55418  -8.11864  1.000 25.03038 ? 12  LEU B CD1 1 
ATOM   1243 C CD2 . LEU B 1 12  ? -21.40743 14.98787  -8.03284  1.000 45.61831 ? 12  LEU B CD2 1 
ATOM   1244 N N   . THR B 1 13  ? -21.81305 13.82697  -3.05281  1.000 38.51252 ? 13  THR B N   1 
ATOM   1245 C CA  . THR B 1 13  ? -21.82788 12.73943  -2.10255  1.000 42.11114 ? 13  THR B CA  1 
ATOM   1246 C C   . THR B 1 13  ? -21.09777 11.53392  -2.68794  1.000 41.49742 ? 13  THR B C   1 
ATOM   1247 O O   . THR B 1 13  ? -20.90387 11.44382  -3.90132  1.000 44.33874 ? 13  THR B O   1 
ATOM   1248 C CB  . THR B 1 13  ? -23.26437 12.35106  -1.77311  1.000 46.80755 ? 13  THR B CB  1 
ATOM   1249 O OG1 . THR B 1 13  ? -23.80459 11.57549  -2.85725  1.000 38.34218 ? 13  THR B OG1 1 
ATOM   1250 C CG2 . THR B 1 13  ? -24.12292 13.60416  -1.55027  1.000 45.14949 ? 13  THR B CG2 1 
ATOM   1251 N N   . PRO B 1 14  ? -20.67224 10.60611  -1.84226  1.000 40.38903 ? 14  PRO B N   1 
ATOM   1252 C CA  . PRO B 1 14  ? -20.14245 9.32932   -2.33937  1.000 41.71058 ? 14  PRO B CA  1 
ATOM   1253 C C   . PRO B 1 14  ? -21.03892 8.58745   -3.32988  1.000 41.37777 ? 14  PRO B C   1 
ATOM   1254 O O   . PRO B 1 14  ? -20.54422 7.75170   -4.08800  1.000 42.87518 ? 14  PRO B O   1 
ATOM   1255 C CB  . PRO B 1 14  ? -19.95193 8.52873   -1.04716  1.000 32.15531 ? 14  PRO B CB  1 
ATOM   1256 C CG  . PRO B 1 14  ? -19.52189 9.57028   -0.07094  1.000 44.22977 ? 14  PRO B CG  1 
ATOM   1257 C CD  . PRO B 1 14  ? -20.26587 10.84980  -0.44822  1.000 42.01265 ? 14  PRO B CD  1 
ATOM   1258 N N   . SER B 1 15  ? -22.34112 8.85169   -3.33816  1.000 40.61301 ? 15  SER B N   1 
ATOM   1259 C CA  . SER B 1 15  ? -23.19744 8.28032   -4.36826  1.000 37.45393 ? 15  SER B CA  1 
ATOM   1260 C C   . SER B 1 15  ? -23.32420 9.18984   -5.58100  1.000 38.14640 ? 15  SER B C   1 
ATOM   1261 O O   . SER B 1 15  ? -23.60220 8.71080   -6.68757  1.000 35.94411 ? 15  SER B O   1 
ATOM   1262 C CB  . SER B 1 15  ? -24.58973 7.98373   -3.80366  1.000 42.91628 ? 15  SER B CB  1 
ATOM   1263 O OG  . SER B 1 15  ? -25.53700 7.85666   -4.85317  1.000 41.21760 ? 15  SER B OG  1 
ATOM   1264 N N   . ALA B 1 16  ? -23.13401 10.49361  -5.39117  1.000 38.85682 ? 16  ALA B N   1 
ATOM   1265 C CA  . ALA B 1 16  ? -23.13800 11.41310  -6.51878  1.000 37.55291 ? 16  ALA B CA  1 
ATOM   1266 C C   . ALA B 1 16  ? -21.88100 11.26376  -7.36494  1.000 33.14434 ? 16  ALA B C   1 
ATOM   1267 O O   . ALA B 1 16  ? -21.91706 11.52352  -8.56990  1.000 31.21448 ? 16  ALA B O   1 
ATOM   1268 C CB  . ALA B 1 16  ? -23.29033 12.84563  -6.01435  1.000 44.98789 ? 16  ALA B CB  1 
ATOM   1269 N N   . LYS B 1 17  ? -20.77078 10.84134  -6.76092  1.000 34.40048 ? 17  LYS B N   1 
ATOM   1270 C CA  . LYS B 1 17  ? -19.59025 10.49550  -7.54527  1.000 32.63314 ? 17  LYS B CA  1 
ATOM   1271 C C   . LYS B 1 17  ? -19.82957 9.23494   -8.36324  1.000 32.68346 ? 17  LYS B C   1 
ATOM   1272 O O   . LYS B 1 17  ? -19.53106 9.19058   -9.56441  1.000 32.55093 ? 17  LYS B O   1 
ATOM   1273 C CB  . LYS B 1 17  ? -18.38121 10.31126  -6.63068  1.000 30.19990 ? 17  LYS B CB  1 
ATOM   1274 C CG  . LYS B 1 17  ? -17.79876 11.59997  -6.08124  1.000 29.13219 ? 17  LYS B CG  1 
ATOM   1275 C CD  . LYS B 1 17  ? -16.59403 11.30705  -5.18515  1.000 26.12664 ? 17  LYS B CD  1 
ATOM   1276 C CE  . LYS B 1 17  ? -15.95067 12.58134  -4.62783  1.000 36.43990 ? 17  LYS B CE  1 
ATOM   1277 N NZ  . LYS B 1 17  ? -16.61370 13.07718  -3.38836  1.000 29.31062 ? 17  LYS B NZ  1 
ATOM   1278 N N   . HIS B 1 18  ? -20.36190 8.19178   -7.72612  1.000 37.58967 ? 18  HIS B N   1 
ATOM   1279 C CA  . HIS B 1 18  ? -20.59062 6.94314   -8.44217  1.000 38.05688 ? 18  HIS B CA  1 
ATOM   1280 C C   . HIS B 1 18  ? -21.50580 7.15967   -9.63914  1.000 35.81710 ? 18  HIS B C   1 
ATOM   1281 O O   . HIS B 1 18  ? -21.26047 6.61596   -10.72453 1.000 40.72329 ? 18  HIS B O   1 
ATOM   1282 C CB  . HIS B 1 18  ? -21.17109 5.88689   -7.50331  1.000 33.48911 ? 18  HIS B CB  1 
ATOM   1283 C CG  . HIS B 1 18  ? -21.44359 4.57410   -8.17600  1.000 41.40075 ? 18  HIS B CG  1 
ATOM   1284 N ND1 . HIS B 1 18  ? -22.66499 3.93827   -8.10689  1.000 41.75417 ? 18  HIS B ND1 1 
ATOM   1285 C CD2 . HIS B 1 18  ? -20.65136 3.78207   -8.93833  1.000 42.69778 ? 18  HIS B CD2 1 
ATOM   1286 C CE1 . HIS B 1 18  ? -22.61070 2.80790   -8.78805  1.000 42.86555 ? 18  HIS B CE1 1 
ATOM   1287 N NE2 . HIS B 1 18  ? -21.40102 2.69055   -9.30486  1.000 43.39275 ? 18  HIS B NE2 1 
ATOM   1288 N N   . ALA B 1 19  ? -22.54909 7.97554   -9.46819  1.000 31.55487 ? 19  ALA B N   1 
ATOM   1289 C CA  . ALA B 1 19  ? -23.50272 8.20721   -10.54844 1.000 28.30398 ? 19  ALA B CA  1 
ATOM   1290 C C   . ALA B 1 19  ? -22.88247 9.02414   -11.67231 1.000 31.01797 ? 19  ALA B C   1 
ATOM   1291 O O   . ALA B 1 19  ? -23.13723 8.76562   -12.85436 1.000 28.17562 ? 19  ALA B O   1 
ATOM   1292 C CB  . ALA B 1 19  ? -24.74714 8.90431   -10.00421 1.000 32.01406 ? 19  ALA B CB  1 
ATOM   1293 N N   . VAL B 1 20  ? -22.06791 10.01840  -11.32414 1.000 32.24657 ? 20  VAL B N   1 
ATOM   1294 C CA  . VAL B 1 20  ? -21.44767 10.83888  -12.35117 1.000 29.62635 ? 20  VAL B CA  1 
ATOM   1295 C C   . VAL B 1 20  ? -20.35877 10.05708  -13.07464 1.000 31.42462 ? 20  VAL B C   1 
ATOM   1296 O O   . VAL B 1 20  ? -20.27141 10.08604  -14.31038 1.000 31.51632 ? 20  VAL B O   1 
ATOM   1297 C CB  . VAL B 1 20  ? -20.92100 12.14144  -11.73269 1.000 31.77813 ? 20  VAL B CB  1 
ATOM   1298 C CG1 . VAL B 1 20  ? -19.45526 12.37143  -12.09474 1.000 28.75719 ? 20  VAL B CG1 1 
ATOM   1299 C CG2 . VAL B 1 20  ? -21.79959 13.30245  -12.18817 1.000 29.97449 ? 20  VAL B CG2 1 
ATOM   1300 N N   . ALA B 1 21  ? -19.53906 9.31425   -12.32488 1.000 31.46742 ? 21  ALA B N   1 
ATOM   1301 C CA  . ALA B 1 21  ? -18.45192 8.55858   -12.93269 1.000 28.83364 ? 21  ALA B CA  1 
ATOM   1302 C C   . ALA B 1 21  ? -18.96307 7.38781   -13.76043 1.000 31.31053 ? 21  ALA B C   1 
ATOM   1303 O O   . ALA B 1 21  ? -18.23116 6.88360   -14.61690 1.000 34.29073 ? 21  ALA B O   1 
ATOM   1304 C CB  . ALA B 1 21  ? -17.48910 8.07439   -11.85163 1.000 22.26750 ? 21  ALA B CB  1 
ATOM   1305 N N   . LYS B 1 22  ? -20.20186 6.95955   -13.52344 1.000 30.11627 ? 22  LYS B N   1 
ATOM   1306 C CA  . LYS B 1 22  ? -20.86009 5.97790   -14.37202 1.000 29.29123 ? 22  LYS B CA  1 
ATOM   1307 C C   . LYS B 1 22  ? -21.41774 6.63089   -15.62977 1.000 31.98576 ? 22  LYS B C   1 
ATOM   1308 O O   . LYS B 1 22  ? -21.22754 6.12169   -16.74012 1.000 34.26866 ? 22  LYS B O   1 
ATOM   1309 C CB  . LYS B 1 22  ? -21.97018 5.28425   -13.57978 1.000 34.84244 ? 22  LYS B CB  1 
ATOM   1310 C CG  . LYS B 1 22  ? -22.84750 4.33315   -14.37768 1.000 39.10838 ? 22  LYS B CG  1 
ATOM   1311 C CD  . LYS B 1 22  ? -24.20217 4.95153   -14.69120 1.000 32.92502 ? 22  LYS B CD  1 
ATOM   1312 C CE  . LYS B 1 22  ? -25.29568 3.89235   -14.64536 1.000 33.95734 ? 22  LYS B CE  1 
ATOM   1313 N NZ  . LYS B 1 22  ? -24.90897 2.67207   -15.40200 1.000 37.28590 ? 22  LYS B NZ  1 
ATOM   1314 N N   . ALA B 1 23  ? -22.11925 7.75541   -15.47000 1.000 34.14839 ? 23  ALA B N   1 
ATOM   1315 C CA  . ALA B 1 23  ? -22.55458 8.53654   -16.62149 1.000 30.39154 ? 23  ALA B CA  1 
ATOM   1316 C C   . ALA B 1 23  ? -21.40335 8.76297   -17.59434 1.000 32.84509 ? 23  ALA B C   1 
ATOM   1317 O O   . ALA B 1 23  ? -21.54381 8.54082   -18.80093 1.000 27.40697 ? 23  ALA B O   1 
ATOM   1318 C CB  . ALA B 1 23  ? -23.14366 9.87260   -16.16481 1.000 21.71449 ? 23  ALA B CB  1 
ATOM   1319 N N   . ILE B 1 24  ? -20.24933 9.19607   -17.08092 1.000 30.97840 ? 24  ILE B N   1 
ATOM   1320 C CA  . ILE B 1 24  ? -19.09698 9.40902   -17.94984 1.000 27.45852 ? 24  ILE B CA  1 
ATOM   1321 C C   . ILE B 1 24  ? -18.73631 8.12048   -18.65875 1.000 29.05377 ? 24  ILE B C   1 
ATOM   1322 O O   . ILE B 1 24  ? -18.54284 8.09394   -19.87874 1.000 33.50127 ? 24  ILE B O   1 
ATOM   1323 C CB  . ILE B 1 24  ? -17.90007 9.94985   -17.15404 1.000 26.23350 ? 24  ILE B CB  1 
ATOM   1324 C CG1 . ILE B 1 24  ? -18.20395 11.34361  -16.59983 1.000 31.29434 ? 24  ILE B CG1 1 
ATOM   1325 C CG2 . ILE B 1 24  ? -16.65932 9.97712   -18.03853 1.000 27.77798 ? 24  ILE B CG2 1 
ATOM   1326 C CD1 . ILE B 1 24  ? -17.34241 11.70259  -15.40644 1.000 26.08584 ? 24  ILE B CD1 1 
ATOM   1327 N N   . THR B 1 25  ? -18.64947 7.02922   -17.90048 1.000 33.28606 ? 25  THR B N   1 
ATOM   1328 C CA  . THR B 1 25  ? -18.14162 5.77248   -18.44732 1.000 33.62279 ? 25  THR B CA  1 
ATOM   1329 C C   . THR B 1 25  ? -19.07560 5.20199   -19.50790 1.000 31.61008 ? 25  THR B C   1 
ATOM   1330 O O   . THR B 1 25  ? -18.61970 4.74938   -20.56383 1.000 30.79778 ? 25  THR B O   1 
ATOM   1331 C CB  . THR B 1 25  ? -17.92910 4.77201   -17.31286 1.000 33.64602 ? 25  THR B CB  1 
ATOM   1332 O OG1 . THR B 1 25  ? -16.84959 5.21905   -16.48105 1.000 23.20733 ? 25  THR B OG1 1 
ATOM   1333 C CG2 . THR B 1 25  ? -17.64320 3.36674   -17.85831 1.000 29.88073 ? 25  THR B CG2 1 
ATOM   1334 N N   . ASP B 1 26  ? -20.38542 5.21697   -19.24719 1.000 35.93523 ? 26  ASP B N   1 
ATOM   1335 C CA  . ASP B 1 26  ? -21.33609 4.75651   -20.25259 1.000 32.49922 ? 26  ASP B CA  1 
ATOM   1336 C C   . ASP B 1 26  ? -21.28601 5.64727   -21.48806 1.000 28.52431 ? 26  ASP B C   1 
ATOM   1337 O O   . ASP B 1 26  ? -21.44346 5.16186   -22.61371 1.000 24.78876 ? 26  ASP B O   1 
ATOM   1338 C CB  . ASP B 1 26  ? -22.76013 4.70275   -19.67833 1.000 32.06009 ? 26  ASP B CB  1 
ATOM   1339 C CG  . ASP B 1 26  ? -22.87946 3.81016   -18.42292 1.000 40.53671 ? 26  ASP B CG  1 
ATOM   1340 O OD1 . ASP B 1 26  ? -21.88030 3.64675   -17.69275 1.000 37.71291 ? 26  ASP B OD1 1 
ATOM   1341 O OD2 . ASP B 1 26  ? -23.98348 3.26963   -18.16270 1.000 36.71525 ? 26  ASP B OD2 1 
ATOM   1342 N N   . ALA B 1 27  ? -21.06125 6.95418   -21.29547 1.000 28.75582 ? 27  ALA B N   1 
ATOM   1343 C CA  . ALA B 1 27  ? -20.94155 7.87031   -22.42745 1.000 24.15868 ? 27  ALA B CA  1 
ATOM   1344 C C   . ALA B 1 27  ? -19.78090 7.47218   -23.32570 1.000 28.72530 ? 27  ALA B C   1 
ATOM   1345 O O   . ALA B 1 27  ? -19.93318 7.34660   -24.54496 1.000 26.03799 ? 27  ALA B O   1 
ATOM   1346 C CB  . ALA B 1 27  ? -20.75551 9.30200   -21.93187 1.000 31.48278 ? 27  ALA B CB  1 
ATOM   1347 N N   . HIS B 1 28  ? -18.60931 7.25560   -22.72949 1.000 32.27114 ? 28  HIS B N   1 
ATOM   1348 C CA  . HIS B 1 28  ? -17.44631 6.83587   -23.49773 1.000 27.45353 ? 28  HIS B CA  1 
ATOM   1349 C C   . HIS B 1 28  ? -17.71602 5.51985   -24.20677 1.000 26.47358 ? 28  HIS B C   1 
ATOM   1350 O O   . HIS B 1 28  ? -17.69642 5.44884   -25.44127 1.000 29.35034 ? 28  HIS B O   1 
ATOM   1351 C CB  . HIS B 1 28  ? -16.23214 6.71302   -22.58096 1.000 27.46638 ? 28  HIS B CB  1 
ATOM   1352 C CG  . HIS B 1 28  ? -14.92325 6.87048   -23.28946 1.000 28.63624 ? 28  HIS B CG  1 
ATOM   1353 N ND1 . HIS B 1 28  ? -14.36270 8.10188   -23.55245 1.000 26.09438 ? 28  HIS B ND1 1 
ATOM   1354 C CD2 . HIS B 1 28  ? -14.07105 5.95183   -23.80069 1.000 25.09526 ? 28  HIS B CD2 1 
ATOM   1355 C CE1 . HIS B 1 28  ? -13.21368 7.93524   -24.17956 1.000 23.43806 ? 28  HIS B CE1 1 
ATOM   1356 N NE2 . HIS B 1 28  ? -13.01819 6.64026   -24.35068 1.000 29.50748 ? 28  HIS B NE2 1 
ATOM   1357 N N   . ARG B 1 29  ? -17.99923 4.47013   -23.43048 1.000 30.27966 ? 29  ARG B N   1 
ATOM   1358 C CA  . ARG B 1 29  ? -18.15779 3.12526   -23.98187 1.000 31.40701 ? 29  ARG B CA  1 
ATOM   1359 C C   . ARG B 1 29  ? -19.15669 3.09141   -25.13570 1.000 28.48391 ? 29  ARG B C   1 
ATOM   1360 O O   . ARG B 1 29  ? -18.89385 2.48865   -26.17934 1.000 30.71905 ? 29  ARG B O   1 
ATOM   1361 C CB  . ARG B 1 29  ? -18.58253 2.15919   -22.87340 1.000 25.84963 ? 29  ARG B CB  1 
ATOM   1362 C CG  . ARG B 1 29  ? -19.10953 0.82869   -23.37140 1.000 33.49064 ? 29  ARG B CG  1 
ATOM   1363 C CD  . ARG B 1 29  ? -20.63189 0.82173   -23.31504 1.000 42.57995 ? 29  ARG B CD  1 
ATOM   1364 N NE  . ARG B 1 29  ? -21.22834 -0.14963  -24.22015 1.000 40.48935 ? 29  ARG B NE  1 
ATOM   1365 C CZ  . ARG B 1 29  ? -22.47329 -0.07148  -24.67224 1.000 50.25301 ? 29  ARG B CZ  1 
ATOM   1366 N NH1 . ARG B 1 29  ? -23.27794 0.91426   -24.30936 1.000 36.73524 ? 29  ARG B NH1 1 
ATOM   1367 N NH2 . ARG B 1 29  ? -22.91622 -0.99673  -25.52417 1.000 55.59823 ? 29  ARG B NH2 1 
ATOM   1368 N N   . GLY B 1 30  ? -20.31938 3.71645   -24.95861 1.000 30.13288 ? 30  GLY B N   1 
ATOM   1369 C CA  . GLY B 1 30  ? -21.30502 3.70176   -26.02056 1.000 25.44735 ? 30  GLY B CA  1 
ATOM   1370 C C   . GLY B 1 30  ? -20.77889 4.34664   -27.28279 1.000 26.61519 ? 30  GLY B C   1 
ATOM   1371 O O   . GLY B 1 30  ? -20.94034 3.80858   -28.37707 1.000 26.65275 ? 30  GLY B O   1 
ATOM   1372 N N   . LEU B 1 31  ? -20.08543 5.47567   -27.13756 1.000 25.58444 ? 31  LEU B N   1 
ATOM   1373 C CA  . LEU B 1 31  ? -19.77137 6.31316   -28.28895 1.000 32.02438 ? 31  LEU B CA  1 
ATOM   1374 C C   . LEU B 1 31  ? -18.54730 5.83142   -29.04893 1.000 30.13078 ? 31  LEU B C   1 
ATOM   1375 O O   . LEU B 1 31  ? -18.50266 5.95838   -30.27401 1.000 30.41000 ? 31  LEU B O   1 
ATOM   1376 C CB  . LEU B 1 31  ? -19.58903 7.76749   -27.83849 1.000 27.44198 ? 31  LEU B CB  1 
ATOM   1377 C CG  . LEU B 1 31  ? -20.96761 8.30073   -27.44243 1.000 32.37588 ? 31  LEU B CG  1 
ATOM   1378 C CD1 . LEU B 1 31  ? -20.94037 9.72634   -26.97284 1.000 38.38312 ? 31  LEU B CD1 1 
ATOM   1379 C CD2 . LEU B 1 31  ? -21.90026 8.15189   -28.62942 1.000 32.84163 ? 31  LEU B CD2 1 
ATOM   1380 N N   . THR B 1 32  ? -17.55196 5.29172   -28.35329 1.000 29.77262 ? 32  THR B N   1 
ATOM   1381 C CA  . THR B 1 32  ? -16.32951 4.86154   -28.99888 1.000 25.76756 ? 32  THR B CA  1 
ATOM   1382 C C   . THR B 1 32  ? -16.14239 3.35514   -29.00849 1.000 26.29869 ? 32  THR B C   1 
ATOM   1383 O O   . THR B 1 32  ? -15.37764 2.85666   -29.83858 1.000 27.76892 ? 32  THR B O   1 
ATOM   1384 C CB  . THR B 1 32  ? -15.11566 5.51037   -28.32024 1.000 24.16346 ? 32  THR B CB  1 
ATOM   1385 O OG1 . THR B 1 32  ? -14.94935 4.95981   -27.01345 1.000 23.62006 ? 32  THR B OG1 1 
ATOM   1386 C CG2 . THR B 1 32  ? -15.33104 6.99005   -28.19832 1.000 21.96939 ? 32  THR B CG2 1 
ATOM   1387 N N   . GLY B 1 33  ? -16.79967 2.62183   -28.11623 1.000 20.37823 ? 33  GLY B N   1 
ATOM   1388 C CA  . GLY B 1 33  ? -16.62933 1.18313   -28.06958 1.000 28.36133 ? 33  GLY B CA  1 
ATOM   1389 C C   . GLY B 1 33  ? -15.48980 0.69092   -27.20301 1.000 27.11801 ? 33  GLY B C   1 
ATOM   1390 O O   . GLY B 1 33  ? -15.25903 -0.52380  -27.14218 1.000 27.71948 ? 33  GLY B O   1 
ATOM   1391 N N   . THR B 1 34  ? -14.76994 1.58917   -26.53975 1.000 26.89594 ? 34  THR B N   1 
ATOM   1392 C CA  . THR B 1 34  ? -13.74488 1.19232   -25.58397 1.000 23.38327 ? 34  THR B CA  1 
ATOM   1393 C C   . THR B 1 34  ? -14.40297 0.61012   -24.33832 1.000 27.93791 ? 34  THR B C   1 
ATOM   1394 O O   . THR B 1 34  ? -15.34145 1.19734   -23.79287 1.000 33.04839 ? 34  THR B O   1 
ATOM   1395 C CB  . THR B 1 34  ? -12.87675 2.40505   -25.23643 1.000 26.42382 ? 34  THR B CB  1 
ATOM   1396 O OG1 . THR B 1 34  ? -12.17313 2.83009   -26.40846 1.000 35.85417 ? 34  THR B OG1 1 
ATOM   1397 C CG2 . THR B 1 34  ? -11.87037 2.09160   -24.14558 1.000 26.96126 ? 34  THR B CG2 1 
ATOM   1398 N N   . GLN B 1 35  ? -13.90770 -0.54693  -23.89175 1.000 31.61870 ? 35  GLN B N   1 
ATOM   1399 C CA  . GLN B 1 35  ? -14.53254 -1.29116  -22.80215 1.000 27.04031 ? 35  GLN B CA  1 
ATOM   1400 C C   . GLN B 1 35  ? -14.59989 -0.45218  -21.52677 1.000 27.10463 ? 35  GLN B C   1 
ATOM   1401 O O   . GLN B 1 35  ? -13.73045 0.38430   -21.26596 1.000 21.85970 ? 35  GLN B O   1 
ATOM   1402 C CB  . GLN B 1 35  ? -13.76032 -2.58731  -22.53088 1.000 24.86694 ? 35  GLN B CB  1 
ATOM   1403 C CG  . GLN B 1 35  ? -13.72408 -3.61255  -23.68066 1.000 28.96549 ? 35  GLN B CG  1 
ATOM   1404 C CD  . GLN B 1 35  ? -12.36882 -3.70493  -24.40215 1.000 20.59460 ? 35  GLN B CD  1 
ATOM   1405 O OE1 . GLN B 1 35  ? -11.79906 -2.70219  -24.79679 1.000 23.42915 ? 35  GLN B OE1 1 
ATOM   1406 N NE2 . GLN B 1 35  ? -11.87292 -4.92484  -24.58936 1.000 22.57422 ? 35  GLN B NE2 1 
ATOM   1407 N N   . HIS B 1 36  ? -15.64611 -0.70867  -20.72222 1.000 32.44367 ? 36  HIS B N   1 
ATOM   1408 C CA  . HIS B 1 36  ? -15.88635 0.03842   -19.48341 1.000 33.55276 ? 36  HIS B CA  1 
ATOM   1409 C C   . HIS B 1 36  ? -14.62671 0.13304   -18.64339 1.000 26.42751 ? 36  HIS B C   1 
ATOM   1410 O O   . HIS B 1 36  ? -14.16524 1.23052   -18.31815 1.000 26.59288 ? 36  HIS B O   1 
ATOM   1411 C CB  . HIS B 1 36  ? -16.99824 -0.61235  -18.64374 1.000 32.53954 ? 36  HIS B CB  1 
ATOM   1412 C CG  . HIS B 1 36  ? -18.37778 -0.13526  -18.97605 1.000 34.94707 ? 36  HIS B CG  1 
ATOM   1413 N ND1 . HIS B 1 36  ? -19.50237 -0.59100  -18.32122 1.000 37.53703 ? 36  HIS B ND1 1 
ATOM   1414 C CD2 . HIS B 1 36  ? -18.81440 0.75798   -19.89337 1.000 38.43517 ? 36  HIS B CD2 1 
ATOM   1415 C CE1 . HIS B 1 36  ? -20.57295 -0.00288  -18.82482 1.000 41.58231 ? 36  HIS B CE1 1 
ATOM   1416 N NE2 . HIS B 1 36  ? -20.18271 0.81974   -19.78227 1.000 43.19773 ? 36  HIS B NE2 1 
ATOM   1417 N N   . PHE B 1 37  ? -14.06100 -1.02577  -18.28476 1.000 24.05579 ? 37  PHE B N   1 
ATOM   1418 C CA  . PHE B 1 37  ? -12.91837 -1.07490  -17.38373 1.000 21.69655 ? 37  PHE B CA  1 
ATOM   1419 C C   . PHE B 1 37  ? -11.74002 -0.24642  -17.87250 1.000 24.65298 ? 37  PHE B C   1 
ATOM   1420 O O   . PHE B 1 37  ? -10.87536 0.10143   -17.06008 1.000 28.79295 ? 37  PHE B O   1 
ATOM   1421 C CB  . PHE B 1 37  ? -12.47338 -2.52630  -17.15825 1.000 27.36612 ? 37  PHE B CB  1 
ATOM   1422 C CG  . PHE B 1 37  ? -12.18143 -3.29216  -18.43191 1.000 28.12391 ? 37  PHE B CG  1 
ATOM   1423 C CD1 . PHE B 1 37  ? -10.95825 -3.17664  -19.06212 1.000 28.89226 ? 37  PHE B CD1 1 
ATOM   1424 C CD2 . PHE B 1 37  ? -13.12430 -4.14929  -18.97811 1.000 30.93501 ? 37  PHE B CD2 1 
ATOM   1425 C CE1 . PHE B 1 37  ? -10.68943 -3.88387  -20.22470 1.000 31.27722 ? 37  PHE B CE1 1 
ATOM   1426 C CE2 . PHE B 1 37  ? -12.86054 -4.86037  -20.13968 1.000 27.50626 ? 37  PHE B CE2 1 
ATOM   1427 C CZ  . PHE B 1 37  ? -11.64725 -4.72307  -20.76277 1.000 30.54827 ? 37  PHE B CZ  1 
ATOM   1428 N N   . LEU B 1 38  ? -11.67909 0.07915   -19.17062 1.000 23.59579 ? 38  LEU B N   1 
ATOM   1429 C CA  . LEU B 1 38  ? -10.61646 0.94795   -19.66581 1.000 24.71067 ? 38  LEU B CA  1 
ATOM   1430 C C   . LEU B 1 38  ? -10.80970 2.40476   -19.26402 1.000 23.75074 ? 38  LEU B C   1 
ATOM   1431 O O   . LEU B 1 38  ? -9.84798  3.17873   -19.32043 1.000 24.33791 ? 38  LEU B O   1 
ATOM   1432 C CB  . LEU B 1 38  ? -10.50797 0.83759   -21.18604 1.000 21.11594 ? 38  LEU B CB  1 
ATOM   1433 C CG  . LEU B 1 38  ? -9.75640  -0.42518  -21.59177 1.000 27.55976 ? 38  LEU B CG  1 
ATOM   1434 C CD1 . LEU B 1 38  ? -9.77465  -0.64635  -23.11314 1.000 22.87948 ? 38  LEU B CD1 1 
ATOM   1435 C CD2 . LEU B 1 38  ? -8.32166  -0.36202  -21.03819 1.000 22.19395 ? 38  LEU B CD2 1 
ATOM   1436 N N   . ALA B 1 39  ? -12.02213 2.79142   -18.86832 1.000 20.23279 ? 39  ALA B N   1 
ATOM   1437 C CA  . ALA B 1 39  ? -12.29416 4.15624   -18.45453 1.000 21.44630 ? 39  ALA B CA  1 
ATOM   1438 C C   . ALA B 1 39  ? -11.94259 4.34166   -16.98350 1.000 20.20760 ? 39  ALA B C   1 
ATOM   1439 O O   . ALA B 1 39  ? -12.14775 3.44755   -16.16556 1.000 20.62278 ? 39  ALA B O   1 
ATOM   1440 C CB  . ALA B 1 39  ? -13.76271 4.50907   -18.69526 1.000 23.70086 ? 39  ALA B CB  1 
ATOM   1441 N N   . GLN B 1 40  ? -11.37514 5.49705   -16.66013 1.000 15.75048 ? 40  GLN B N   1 
ATOM   1442 C CA  . GLN B 1 40  ? -11.05127 5.85572   -15.29194 1.000 18.25970 ? 40  GLN B CA  1 
ATOM   1443 C C   . GLN B 1 40  ? -11.60547 7.24297   -15.00872 1.000 23.17175 ? 40  GLN B C   1 
ATOM   1444 O O   . GLN B 1 40  ? -11.41179 8.16584   -15.80531 1.000 18.81173 ? 40  GLN B O   1 
ATOM   1445 C CB  . GLN B 1 40  ? -9.54119  5.83169   -15.02721 1.000 16.85435 ? 40  GLN B CB  1 
ATOM   1446 C CG  . GLN B 1 40  ? -9.19953  6.37865   -13.64368 1.000 23.35330 ? 40  GLN B CG  1 
ATOM   1447 C CD  . GLN B 1 40  ? -7.71805  6.33534   -13.30758 1.000 18.90590 ? 40  GLN B CD  1 
ATOM   1448 O OE1 . GLN B 1 40  ? -7.25386  7.04395   -12.41490 1.000 19.86726 ? 40  GLN B OE1 1 
ATOM   1449 N NE2 . GLN B 1 40  ? -6.97494  5.48804   -14.00442 1.000 28.06074 ? 40  GLN B NE2 1 
ATOM   1450 N N   . VAL B 1 41  ? -12.28384 7.39092   -13.87480 1.000 20.34665 ? 41  VAL B N   1 
ATOM   1451 C CA  . VAL B 1 41  ? -12.82245 8.67464   -13.44224 1.000 18.59580 ? 41  VAL B CA  1 
ATOM   1452 C C   . VAL B 1 41  ? -12.17452 9.03150   -12.11427 1.000 19.72969 ? 41  VAL B C   1 
ATOM   1453 O O   . VAL B 1 41  ? -12.37534 8.33228   -11.11180 1.000 24.40044 ? 41  VAL B O   1 
ATOM   1454 C CB  . VAL B 1 41  ? -14.34894 8.64610   -13.31165 1.000 18.95629 ? 41  VAL B CB  1 
ATOM   1455 C CG1 . VAL B 1 41  ? -14.90716 10.08356  -13.22124 1.000 17.27382 ? 41  VAL B CG1 1 
ATOM   1456 C CG2 . VAL B 1 41  ? -14.96420 7.87883   -14.45325 1.000 18.42267 ? 41  VAL B CG2 1 
ATOM   1457 N N   . ASN B 1 42  ? -11.43195 10.13662  -12.09949 1.000 16.34194 ? 42  ASN B N   1 
ATOM   1458 C CA  . ASN B 1 42  ? -10.56596 10.51593  -10.98161 1.000 16.78790 ? 42  ASN B CA  1 
ATOM   1459 C C   . ASN B 1 42  ? -10.97694 11.90194  -10.47188 1.000 17.43406 ? 42  ASN B C   1 
ATOM   1460 O O   . ASN B 1 42  ? -10.56393 12.92122  -11.02494 1.000 21.00064 ? 42  ASN B O   1 
ATOM   1461 C CB  . ASN B 1 42  ? -9.10658  10.48204  -11.43008 1.000 20.32165 ? 42  ASN B CB  1 
ATOM   1462 C CG  . ASN B 1 42  ? -8.13648  10.77385  -10.31528 1.000 18.34089 ? 42  ASN B CG  1 
ATOM   1463 O OD1 . ASN B 1 42  ? -8.35709  11.67356  -9.51362  1.000 20.60480 ? 42  ASN B OD1 1 
ATOM   1464 N ND2 . ASN B 1 42  ? -7.04152  10.01766  -10.26637 1.000 12.28216 ? 42  ASN B ND2 1 
ATOM   1465 N N   . PHE B 1 43  ? -11.77984 11.93949  -9.41018  1.000 24.04757 ? 43  PHE B N   1 
ATOM   1466 C CA  . PHE B 1 43  ? -12.30874 13.18945  -8.86840  1.000 26.90875 ? 43  PHE B CA  1 
ATOM   1467 C C   . PHE B 1 43  ? -11.23327 13.93127  -8.08828  1.000 29.73590 ? 43  PHE B C   1 
ATOM   1468 O O   . PHE B 1 43  ? -10.75147 13.43147  -7.06070  1.000 21.53967 ? 43  PHE B O   1 
ATOM   1469 C CB  . PHE B 1 43  ? -13.49767 12.92270  -7.94808  1.000 24.88247 ? 43  PHE B CB  1 
ATOM   1470 C CG  . PHE B 1 43  ? -14.66107 12.32401  -8.63360  1.000 21.42094 ? 43  PHE B CG  1 
ATOM   1471 C CD1 . PHE B 1 43  ? -14.69594 10.97194  -8.89905  1.000 22.12838 ? 43  PHE B CD1 1 
ATOM   1472 C CD2 . PHE B 1 43  ? -15.72240 13.10275  -9.02532  1.000 20.81299 ? 43  PHE B CD2 1 
ATOM   1473 C CE1 . PHE B 1 43  ? -15.76081 10.41908  -9.54667  1.000 23.15035 ? 43  PHE B CE1 1 
ATOM   1474 C CE2 . PHE B 1 43  ? -16.78522 12.54465  -9.66601  1.000 17.03181 ? 43  PHE B CE2 1 
ATOM   1475 C CZ  . PHE B 1 43  ? -16.80686 11.20279  -9.92593  1.000 20.71876 ? 43  PHE B CZ  1 
ATOM   1476 N N   . GLN B 1 44  ? -10.89148 15.13647  -8.55863  1.000 25.71167 ? 44  GLN B N   1 
ATOM   1477 C CA  . GLN B 1 44  ? -9.96868  16.03531  -7.87126  1.000 23.50403 ? 44  GLN B CA  1 
ATOM   1478 C C   . GLN B 1 44  ? -10.77824 17.06264  -7.08844  1.000 29.62579 ? 44  GLN B C   1 
ATOM   1479 O O   . GLN B 1 44  ? -11.38325 17.96768  -7.66991  1.000 26.30486 ? 44  GLN B O   1 
ATOM   1480 C CB  . GLN B 1 44  ? -9.03185  16.72392  -8.85813  1.000 22.41279 ? 44  GLN B CB  1 
ATOM   1481 C CG  . GLN B 1 44  ? -8.11742  15.77475  -9.58197  1.000 29.03262 ? 44  GLN B CG  1 
ATOM   1482 C CD  . GLN B 1 44  ? -7.03068  15.18349  -8.69419  1.000 25.21662 ? 44  GLN B CD  1 
ATOM   1483 O OE1 . GLN B 1 44  ? -6.17265  15.90074  -8.18648  1.000 27.54907 ? 44  GLN B OE1 1 
ATOM   1484 N NE2 . GLN B 1 44  ? -7.04913  13.86042  -8.53220  1.000 21.35958 ? 44  GLN B NE2 1 
ATOM   1485 N N   . GLU B 1 45  ? -10.76924 16.93073  -5.76824  1.000 35.98814 ? 45  GLU B N   1 
ATOM   1486 C CA  . GLU B 1 45  ? -11.52507 17.79464  -4.87644  1.000 27.45517 ? 45  GLU B CA  1 
ATOM   1487 C C   . GLU B 1 45  ? -10.61932 18.84499  -4.25328  1.000 30.04364 ? 45  GLU B C   1 
ATOM   1488 O O   . GLU B 1 45  ? -9.46226  18.56965  -3.91767  1.000 32.42427 ? 45  GLU B O   1 
ATOM   1489 C CB  . GLU B 1 45  ? -12.19568 16.96794  -3.78465  1.000 31.94953 ? 45  GLU B CB  1 
ATOM   1490 C CG  . GLU B 1 45  ? -13.40189 16.21452  -4.25879  1.000 30.75346 ? 45  GLU B CG  1 
ATOM   1491 C CD  . GLU B 1 45  ? -13.77878 15.10000  -3.31595  1.000 28.38420 ? 45  GLU B CD  1 
ATOM   1492 O OE1 . GLU B 1 45  ? -12.95250 14.20156  -3.10043  1.000 26.59465 ? 45  GLU B OE1 1 
ATOM   1493 O OE2 . GLU B 1 45  ? -14.89619 15.12731  -2.78194  1.000 26.96165 ? 45  GLU B OE2 1 
ATOM   1494 N N   . GLN B 1 46  ? -11.16575 20.05064  -4.09930  1.000 34.24777 ? 46  GLN B N   1 
ATOM   1495 C CA  . GLN B 1 46  ? -10.50101 21.22312  -3.55773  1.000 35.33108 ? 46  GLN B CA  1 
ATOM   1496 C C   . GLN B 1 46  ? -11.52737 22.02286  -2.77225  1.000 37.41550 ? 46  GLN B C   1 
ATOM   1497 O O   . GLN B 1 46  ? -12.69379 22.08221  -3.18520  1.000 37.66165 ? 46  GLN B O   1 
ATOM   1498 C CB  . GLN B 1 46  ? -9.90436  22.10442  -4.66495  1.000 33.11003 ? 46  GLN B CB  1 
ATOM   1499 C CG  . GLN B 1 46  ? -8.56629  21.63759  -5.15898  1.000 31.13536 ? 46  GLN B CG  1 
ATOM   1500 C CD  . GLN B 1 46  ? -7.45133  21.99001  -4.21125  1.000 29.63622 ? 46  GLN B CD  1 
ATOM   1501 O OE1 . GLN B 1 46  ? -7.34770  23.12365  -3.73963  1.000 26.87365 ? 46  GLN B OE1 1 
ATOM   1502 N NE2 . GLN B 1 46  ? -6.61872  21.01188  -3.90686  1.000 25.91537 ? 46  GLN B NE2 1 
ATOM   1503 N N   . PRO B 1 47  ? -11.13688 22.68033  -1.68446  1.000 36.80869 ? 47  PRO B N   1 
ATOM   1504 C CA  . PRO B 1 47  ? -12.12368 23.45636  -0.93432  1.000 35.95727 ? 47  PRO B CA  1 
ATOM   1505 C C   . PRO B 1 47  ? -12.60045 24.61395  -1.79626  1.000 38.63269 ? 47  PRO B C   1 
ATOM   1506 O O   . PRO B 1 47  ? -11.79530 25.29154  -2.44075  1.000 34.60101 ? 47  PRO B O   1 
ATOM   1507 C CB  . PRO B 1 47  ? -11.34532 23.92744  0.29803   1.000 31.88191 ? 47  PRO B CB  1 
ATOM   1508 C CG  . PRO B 1 47  ? -9.89190  23.80932  -0.06686  1.000 34.70889 ? 47  PRO B CG  1 
ATOM   1509 C CD  . PRO B 1 47  ? -9.76506  23.13277  -1.39641  1.000 35.03735 ? 47  PRO B CD  1 
ATOM   1510 N N   . ALA B 1 48  ? -13.92611 24.80462  -1.84008  1.000 38.85965 ? 48  ALA B N   1 
ATOM   1511 C CA  . ALA B 1 48  ? -14.56178 25.76899  -2.73340  1.000 29.96266 ? 48  ALA B CA  1 
ATOM   1512 C C   . ALA B 1 48  ? -13.90986 27.14129  -2.65798  1.000 37.11709 ? 48  ALA B C   1 
ATOM   1513 O O   . ALA B 1 48  ? -13.15692 27.44096  -1.72286  1.000 42.20051 ? 48  ALA B O   1 
ATOM   1514 C CB  . ALA B 1 48  ? -16.05075 25.89508  -2.42622  1.000 27.15679 ? 48  ALA B CB  1 
ATOM   1515 N N   . GLY B 1 49  ? -14.20043 27.98913  -3.63433  1.000 31.09406 ? 49  GLY B N   1 
ATOM   1516 C CA  . GLY B 1 49  ? -13.49179 29.24568  -3.72625  1.000 34.85223 ? 49  GLY B CA  1 
ATOM   1517 C C   . GLY B 1 49  ? -12.07981 29.12647  -4.24905  1.000 37.98041 ? 49  GLY B C   1 
ATOM   1518 O O   . GLY B 1 49  ? -11.25786 30.02210  -4.02812  1.000 37.46659 ? 49  GLY B O   1 
ATOM   1519 N N   . ASN B 1 50  ? -11.76022 28.02878  -4.91913  1.000 34.16224 ? 50  ASN B N   1 
ATOM   1520 C CA  . ASN B 1 50  ? -10.52635 27.93595  -5.66614  1.000 32.55124 ? 50  ASN B CA  1 
ATOM   1521 C C   . ASN B 1 50  ? -10.73216 28.04976  -7.17025  1.000 31.26558 ? 50  ASN B C   1 
ATOM   1522 O O   . ASN B 1 50  ? -9.74746  28.20072  -7.89536  1.000 36.99118 ? 50  ASN B O   1 
ATOM   1523 C CB  . ASN B 1 50  ? -9.80587  26.62452  -5.32102  1.000 37.68082 ? 50  ASN B CB  1 
ATOM   1524 C CG  . ASN B 1 50  ? -9.10608  26.69043  -3.97572  1.000 29.98319 ? 50  ASN B CG  1 
ATOM   1525 O OD1 . ASN B 1 50  ? -9.32790  27.61649  -3.19113  1.000 38.24992 ? 50  ASN B OD1 1 
ATOM   1526 N ND2 . ASN B 1 50  ? -8.24771  25.72489  -3.71109  1.000 28.50897 ? 50  ASN B ND2 1 
ATOM   1527 N N   . VAL B 1 51  ? -11.97109 27.99880  -7.65470  1.000 29.43309 ? 51  VAL B N   1 
ATOM   1528 C CA  . VAL B 1 51  ? -12.27746 28.24744  -9.05934  1.000 25.90760 ? 51  VAL B CA  1 
ATOM   1529 C C   . VAL B 1 51  ? -12.61793 29.71939  -9.22335  1.000 32.67837 ? 51  VAL B C   1 
ATOM   1530 O O   . VAL B 1 51  ? -13.68023 30.17258  -8.78505  1.000 36.77756 ? 51  VAL B O   1 
ATOM   1531 C CB  . VAL B 1 51  ? -13.44359 27.39127  -9.56471  1.000 25.85051 ? 51  VAL B CB  1 
ATOM   1532 C CG1 . VAL B 1 51  ? -13.68706 27.70241  -11.06506 1.000 29.23472 ? 51  VAL B CG1 1 
ATOM   1533 C CG2 . VAL B 1 51  ? -13.21650 25.91349  -9.29251  1.000 17.77920 ? 51  VAL B CG2 1 
ATOM   1534 N N   . PHE B 1 52  ? -11.73580 30.45436  -9.87722  1.000 27.15061 ? 52  PHE B N   1 
ATOM   1535 C CA  . PHE B 1 52  ? -12.00599 31.81742  -10.29700 1.000 32.82873 ? 52  PHE B CA  1 
ATOM   1536 C C   . PHE B 1 52  ? -12.40095 31.82588  -11.76593 1.000 31.40734 ? 52  PHE B C   1 
ATOM   1537 O O   . PHE B 1 52  ? -12.04526 30.93141  -12.53846 1.000 28.34155 ? 52  PHE B O   1 
ATOM   1538 C CB  . PHE B 1 52  ? -10.79288 32.71902  -10.05656 1.000 33.34725 ? 52  PHE B CB  1 
ATOM   1539 C CG  . PHE B 1 52  ? -10.49894 32.95659  -8.59762  1.000 34.69558 ? 52  PHE B CG  1 
ATOM   1540 C CD1 . PHE B 1 52  ? -9.95098  31.95056  -7.81363  1.000 37.21587 ? 52  PHE B CD1 1 
ATOM   1541 C CD2 . PHE B 1 52  ? -10.77471 34.17489  -8.00971  1.000 34.48426 ? 52  PHE B CD2 1 
ATOM   1542 C CE1 . PHE B 1 52  ? -9.68354  32.15581  -6.46538  1.000 40.46939 ? 52  PHE B CE1 1 
ATOM   1543 C CE2 . PHE B 1 52  ? -10.51495 34.39112  -6.66578  1.000 42.71657 ? 52  PHE B CE2 1 
ATOM   1544 C CZ  . PHE B 1 52  ? -9.97069  33.37944  -5.88822  1.000 41.67335 ? 52  PHE B CZ  1 
ATOM   1545 N N   . LEU B 1 53  ? -13.12638 32.87559  -12.14067 1.000 34.35646 ? 53  LEU B N   1 
ATOM   1546 C CA  . LEU B 1 53  ? -13.87363 32.90915  -13.38955 1.000 22.53770 ? 53  LEU B CA  1 
ATOM   1547 C C   . LEU B 1 53  ? -14.00078 34.37738  -13.78968 1.000 35.23160 ? 53  LEU B C   1 
ATOM   1548 O O   . LEU B 1 53  ? -14.88382 35.08372  -13.28926 1.000 35.42570 ? 53  LEU B O   1 
ATOM   1549 C CB  . LEU B 1 53  ? -15.23035 32.26251  -13.19122 1.000 28.00660 ? 53  LEU B CB  1 
ATOM   1550 C CG  . LEU B 1 53  ? -15.81509 31.46037  -14.33576 1.000 37.54915 ? 53  LEU B CG  1 
ATOM   1551 C CD1 . LEU B 1 53  ? -14.83112 30.37352  -14.66249 1.000 35.47138 ? 53  LEU B CD1 1 
ATOM   1552 C CD2 . LEU B 1 53  ? -17.11292 30.86627  -13.87758 1.000 37.42064 ? 53  LEU B CD2 1 
ATOM   1553 N N   . GLY B 1 54  ? -13.12248 34.83102  -14.68389 1.000 30.32687 ? 54  GLY B N   1 
ATOM   1554 C CA  . GLY B 1 54  ? -13.05488 36.24302  -15.01098 1.000 36.53668 ? 54  GLY B CA  1 
ATOM   1555 C C   . GLY B 1 54  ? -12.69605 37.10153  -13.82359 1.000 42.68869 ? 54  GLY B C   1 
ATOM   1556 O O   . GLY B 1 54  ? -13.24761 38.19814  -13.66369 1.000 41.37451 ? 54  GLY B O   1 
ATOM   1557 N N   . GLY B 1 55  ? -11.77539 36.61740  -12.98629 1.000 39.86350 ? 55  GLY B N   1 
ATOM   1558 C CA  . GLY B 1 55  ? -11.44213 37.20374  -11.71497 1.000 38.32797 ? 55  GLY B CA  1 
ATOM   1559 C C   . GLY B 1 55  ? -12.46647 36.98963  -10.61904 1.000 38.80249 ? 55  GLY B C   1 
ATOM   1560 O O   . GLY B 1 55  ? -12.21284 37.38926  -9.48552  1.000 31.07519 ? 55  GLY B O   1 
ATOM   1561 N N   . VAL B 1 56  ? -13.61021 36.38064  -10.91174 1.000 39.30883 ? 56  VAL B N   1 
ATOM   1562 C CA  . VAL B 1 56  ? -14.71556 36.30537  -9.96524  1.000 35.29750 ? 56  VAL B CA  1 
ATOM   1563 C C   . VAL B 1 56  ? -14.67203 34.94881  -9.27356  1.000 41.93757 ? 56  VAL B C   1 
ATOM   1564 O O   . VAL B 1 56  ? -14.87935 33.89845  -9.89829  1.000 34.46437 ? 56  VAL B O   1 
ATOM   1565 C CB  . VAL B 1 56  ? -16.06203 36.55273  -10.64923 1.000 35.44054 ? 56  VAL B CB  1 
ATOM   1566 C CG1 . VAL B 1 56  ? -17.18004 36.36606  -9.66465  1.000 40.92775 ? 56  VAL B CG1 1 
ATOM   1567 C CG2 . VAL B 1 56  ? -16.08329 37.95597  -11.23513 1.000 33.63860 ? 56  VAL B CG2 1 
ATOM   1568 N N   . GLN B 1 57  ? -14.36658 34.99368  -7.97706  1.000 38.77377 ? 57  GLN B N   1 
ATOM   1569 C CA  . GLN B 1 57  ? -14.47079 33.83358  -7.10713  1.000 39.94378 ? 57  GLN B CA  1 
ATOM   1570 C C   . GLN B 1 57  ? -15.84495 33.19973  -7.22977  1.000 48.43553 ? 57  GLN B C   1 
ATOM   1571 O O   . GLN B 1 57  ? -16.86566 33.89332  -7.23181  1.000 50.66494 ? 57  GLN B O   1 
ATOM   1572 C CB  . GLN B 1 57  ? -14.22451 34.25766  -5.66128  1.000 43.55181 ? 57  GLN B CB  1 
ATOM   1573 C CG  . GLN B 1 57  ? -14.81255 33.32851  -4.63157  1.000 43.50142 ? 57  GLN B CG  1 
ATOM   1574 C CD  . GLN B 1 57  ? -13.78449 32.90700  -3.61879  1.000 32.69656 ? 57  GLN B CD  1 
ATOM   1575 O OE1 . GLN B 1 57  ? -12.87014 32.15635  -3.93022  1.000 35.08666 ? 57  GLN B OE1 1 
ATOM   1576 N NE2 . GLN B 1 57  ? -13.90337 33.42102  -2.41134  1.000 37.62678 ? 57  GLN B NE2 1 
ATOM   1577 N N   . GLN B 1 58  ? -15.86737 31.87562  -7.33987  1.000 41.25038 ? 58  GLN B N   1 
ATOM   1578 C CA  . GLN B 1 58  ? -17.10962 31.14329  -7.50214  1.000 38.79542 ? 58  GLN B CA  1 
ATOM   1579 C C   . GLN B 1 58  ? -17.39711 30.31421  -6.26170  1.000 40.59473 ? 58  GLN B C   1 
ATOM   1580 O O   . GLN B 1 58  ? -16.52231 30.06502  -5.43101  1.000 35.04714 ? 58  GLN B O   1 
ATOM   1581 C CB  . GLN B 1 58  ? -17.06173 30.23602  -8.73479  1.000 39.69990 ? 58  GLN B CB  1 
ATOM   1582 C CG  . GLN B 1 58  ? -17.86062 30.74977  -9.92364  1.000 39.03964 ? 58  GLN B CG  1 
ATOM   1583 C CD  . GLN B 1 58  ? -19.36640 30.57829  -9.75203  1.000 49.45215 ? 58  GLN B CD  1 
ATOM   1584 O OE1 . GLN B 1 58  ? -19.88980 30.51431  -8.62465  1.000 38.20736 ? 58  GLN B OE1 1 
ATOM   1585 N NE2 . GLN B 1 58  ? -20.07649 30.50614  -10.87927 1.000 46.11008 ? 58  GLN B NE2 1 
ATOM   1586 N N   . GLY B 1 59  ? -18.64654 29.89491  -6.14038  1.000 38.29856 ? 59  GLY B N   1 
ATOM   1587 C CA  . GLY B 1 59  ? -18.99376 28.97589  -5.08789  1.000 35.66135 ? 59  GLY B CA  1 
ATOM   1588 C C   . GLY B 1 59  ? -18.38853 27.61350  -5.33735  1.000 39.86361 ? 59  GLY B C   1 
ATOM   1589 O O   . GLY B 1 59  ? -17.31444 27.48960  -5.93822  1.000 39.06175 ? 59  GLY B O   1 
ATOM   1590 N N   . GLY B 1 60  ? -19.07340 26.57900  -4.87262  1.000 37.86617 ? 60  GLY B N   1 
ATOM   1591 C CA  . GLY B 1 60  ? -18.59309 25.23164  -5.05537  1.000 38.54627 ? 60  GLY B CA  1 
ATOM   1592 C C   . GLY B 1 60  ? -19.47306 24.46765  -6.01489  1.000 41.84778 ? 60  GLY B C   1 
ATOM   1593 O O   . GLY B 1 60  ? -19.73358 23.28259  -5.81102  1.000 43.05617 ? 60  GLY B O   1 
ATOM   1594 N N   . ASP B 1 61  ? -19.94080 25.13352  -7.06529  1.000 36.45259 ? 61  ASP B N   1 
ATOM   1595 C CA  . ASP B 1 61  ? -20.88594 24.54422  -8.00596  1.000 38.96376 ? 61  ASP B CA  1 
ATOM   1596 C C   . ASP B 1 61  ? -20.31751 24.47800  -9.42125  1.000 32.95839 ? 61  ASP B C   1 
ATOM   1597 O O   . ASP B 1 61  ? -21.06420 24.55382  -10.39445 1.000 33.46629 ? 61  ASP B O   1 
ATOM   1598 C CB  . ASP B 1 61  ? -22.19435 25.33348  -8.00809  1.000 35.20117 ? 61  ASP B CB  1 
ATOM   1599 C CG  . ASP B 1 61  ? -23.40066 24.46211  -7.79904  1.000 35.71656 ? 61  ASP B CG  1 
ATOM   1600 O OD1 . ASP B 1 61  ? -23.24477 23.34378  -7.28170  1.000 39.17535 ? 61  ASP B OD1 1 
ATOM   1601 O OD2 . ASP B 1 61  ? -24.51234 24.89599  -8.14805  1.000 44.79705 ? 61  ASP B OD2 1 
ATOM   1602 N N   . THR B 1 62  ? -19.00353 24.38231  -9.56859  1.000 31.52681 ? 62  THR B N   1 
ATOM   1603 C CA  . THR B 1 62  ? -18.40929 24.30319  -10.89549 1.000 31.80416 ? 62  THR B CA  1 
ATOM   1604 C C   . THR B 1 62  ? -17.69663 22.96841  -11.05737 1.000 32.42445 ? 62  THR B C   1 
ATOM   1605 O O   . THR B 1 62  ? -17.06154 22.46482  -10.12149 1.000 31.01580 ? 62  THR B O   1 
ATOM   1606 C CB  . THR B 1 62  ? -17.42895 25.45145  -11.17530 1.000 31.51874 ? 62  THR B CB  1 
ATOM   1607 O OG1 . THR B 1 62  ? -17.96698 26.67909  -10.67157 1.000 35.58589 ? 62  THR B OG1 1 
ATOM   1608 C CG2 . THR B 1 62  ? -17.24326 25.59116  -12.68201 1.000 30.34470 ? 62  THR B CG2 1 
ATOM   1609 N N   . ILE B 1 63  ? -17.83435 22.38898  -12.24184 1.000 23.22331 ? 63  ILE B N   1 
ATOM   1610 C CA  . ILE B 1 63  ? -17.25926 21.09440  -12.56097 1.000 25.99655 ? 63  ILE B CA  1 
ATOM   1611 C C   . ILE B 1 63  ? -16.44169 21.24667  -13.83399 1.000 24.52893 ? 63  ILE B C   1 
ATOM   1612 O O   . ILE B 1 63  ? -16.96198 21.69858  -14.86840 1.000 21.76288 ? 63  ILE B O   1 
ATOM   1613 C CB  . ILE B 1 63  ? -18.34032 20.01145  -12.72474 1.000 22.59118 ? 63  ILE B CB  1 
ATOM   1614 C CG1 . ILE B 1 63  ? -18.99498 19.72877  -11.36506 1.000 26.21236 ? 63  ILE B CG1 1 
ATOM   1615 C CG2 . ILE B 1 63  ? -17.73003 18.74800  -13.29885 1.000 22.91614 ? 63  ILE B CG2 1 
ATOM   1616 C CD1 . ILE B 1 63  ? -20.51085 19.65881  -11.39763 1.000 26.25591 ? 63  ILE B CD1 1 
ATOM   1617 N N   . PHE B 1 64  ? -15.16265 20.89427  -13.75589 1.000 21.04775 ? 64  PHE B N   1 
ATOM   1618 C CA  . PHE B 1 64  ? -14.30223 20.86953  -14.92925 1.000 19.81236 ? 64  PHE B CA  1 
ATOM   1619 C C   . PHE B 1 64  ? -13.89266 19.44038  -15.21490 1.000 18.58384 ? 64  PHE B C   1 
ATOM   1620 O O   . PHE B 1 64  ? -13.29474 18.78204  -14.35783 1.000 22.18679 ? 64  PHE B O   1 
ATOM   1621 C CB  . PHE B 1 64  ? -13.05520 21.73158  -14.76489 1.000 25.91836 ? 64  PHE B CB  1 
ATOM   1622 C CG  . PHE B 1 64  ? -12.11784 21.61026  -15.92105 1.000 20.91596 ? 64  PHE B CG  1 
ATOM   1623 C CD1 . PHE B 1 64  ? -12.57463 21.83711  -17.20062 1.000 17.94771 ? 64  PHE B CD1 1 
ATOM   1624 C CD2 . PHE B 1 64  ? -10.81080 21.22468  -15.74162 1.000 19.44628 ? 64  PHE B CD2 1 
ATOM   1625 C CE1 . PHE B 1 64  ? -11.74494 21.72400  -18.27367 1.000 21.23447 ? 64  PHE B CE1 1 
ATOM   1626 C CE2 . PHE B 1 64  ? -9.97213  21.09513  -16.82426 1.000 23.35499 ? 64  PHE B CE2 1 
ATOM   1627 C CZ  . PHE B 1 64  ? -10.43774 21.34648  -18.09144 1.000 17.65361 ? 64  PHE B CZ  1 
ATOM   1628 N N   . VAL B 1 65  ? -14.21329 18.97163  -16.41559 1.000 21.49667 ? 65  VAL B N   1 
ATOM   1629 C CA  . VAL B 1 65  ? -13.85753 17.63280  -16.86179 1.000 18.59468 ? 65  VAL B CA  1 
ATOM   1630 C C   . VAL B 1 65  ? -12.70838 17.76230  -17.85441 1.000 19.69510 ? 65  VAL B C   1 
ATOM   1631 O O   . VAL B 1 65  ? -12.83697 18.41944  -18.89246 1.000 18.25389 ? 65  VAL B O   1 
ATOM   1632 C CB  . VAL B 1 65  ? -15.05132 16.89999  -17.49256 1.000 20.91362 ? 65  VAL B CB  1 
ATOM   1633 C CG1 . VAL B 1 65  ? -14.71873 15.41772  -17.65504 1.000 28.40171 ? 65  VAL B CG1 1 
ATOM   1634 C CG2 . VAL B 1 65  ? -16.33857 17.10159  -16.66905 1.000 14.56922 ? 65  VAL B CG2 1 
ATOM   1635 N N   . HIS B 1 66  ? -11.58358 17.14402  -17.53068 1.000 22.60374 ? 66  HIS B N   1 
ATOM   1636 C CA  . HIS B 1 66  ? -10.46135 17.00486  -18.44224 1.000 14.65578 ? 66  HIS B CA  1 
ATOM   1637 C C   . HIS B 1 66  ? -10.36344 15.54162  -18.85403 1.000 15.61354 ? 66  HIS B C   1 
ATOM   1638 O O   . HIS B 1 66  ? -10.08807 14.66614  -18.02045 1.000 16.56690 ? 66  HIS B O   1 
ATOM   1639 C CB  . HIS B 1 66  ? -9.16999  17.49181  -17.78450 1.000 15.98138 ? 66  HIS B CB  1 
ATOM   1640 C CG  . HIS B 1 66  ? -8.05932  17.79123  -18.74691 1.000 15.25312 ? 66  HIS B CG  1 
ATOM   1641 N ND1 . HIS B 1 66  ? -6.76572  18.03875  -18.33363 1.000 15.74765 ? 66  HIS B ND1 1 
ATOM   1642 C CD2 . HIS B 1 66  ? -8.05076  17.90308  -20.09568 1.000 15.08170 ? 66  HIS B CD2 1 
ATOM   1643 C CE1 . HIS B 1 66  ? -6.00936  18.28139  -19.38687 1.000 13.55813 ? 66  HIS B CE1 1 
ATOM   1644 N NE2 . HIS B 1 66  ? -6.76126  18.19304  -20.46897 1.000 14.61080 ? 66  HIS B NE2 1 
ATOM   1645 N N   . GLY B 1 67  ? -10.60759 15.27918  -20.13537 1.000 18.46545 ? 67  GLY B N   1 
ATOM   1646 C CA  . GLY B 1 67  ? -10.41672 13.96615  -20.71072 1.000 15.43225 ? 67  GLY B CA  1 
ATOM   1647 C C   . GLY B 1 67  ? -9.03594  13.85045  -21.32809 1.000 16.76442 ? 67  GLY B C   1 
ATOM   1648 O O   . GLY B 1 67  ? -8.45751  14.83411  -21.78818 1.000 24.65743 ? 67  GLY B O   1 
ATOM   1649 N N   . LEU B 1 68  ? -8.50057  12.64049  -21.30290 1.000 13.25382 ? 68  LEU B N   1 
ATOM   1650 C CA  . LEU B 1 68  ? -7.23506  12.31622  -21.94554 1.000 15.97294 ? 68  LEU B CA  1 
ATOM   1651 C C   . LEU B 1 68  ? -7.49275  11.05419  -22.75040 1.000 14.71061 ? 68  LEU B C   1 
ATOM   1652 O O   . LEU B 1 68  ? -7.61401  9.96876   -22.18440 1.000 15.87277 ? 68  LEU B O   1 
ATOM   1653 C CB  . LEU B 1 68  ? -6.12421  12.11443  -20.92352 1.000 17.14583 ? 68  LEU B CB  1 
ATOM   1654 C CG  . LEU B 1 68  ? -6.01327  13.25790  -19.92570 1.000 13.87241 ? 68  LEU B CG  1 
ATOM   1655 C CD1 . LEU B 1 68  ? -5.24214  12.88185  -18.64100 1.000 11.59666 ? 68  LEU B CD1 1 
ATOM   1656 C CD2 . LEU B 1 68  ? -5.40707  14.46221  -20.58510 1.000 12.31488 ? 68  LEU B CD2 1 
ATOM   1657 N N   . HIS B 1 69  ? -7.62536  11.21956  -24.06089 1.000 23.00088 ? 69  HIS B N   1 
ATOM   1658 C CA  . HIS B 1 69  ? -7.91165  10.15475  -25.00186 1.000 13.99576 ? 69  HIS B CA  1 
ATOM   1659 C C   . HIS B 1 69  ? -6.65795  9.86704   -25.80430 1.000 17.77122 ? 69  HIS B C   1 
ATOM   1660 O O   . HIS B 1 69  ? -5.68547  10.62253  -25.78161 1.000 18.03352 ? 69  HIS B O   1 
ATOM   1661 C CB  . HIS B 1 69  ? -9.05972  10.54210  -25.95123 1.000 19.72076 ? 69  HIS B CB  1 
ATOM   1662 C CG  . HIS B 1 69  ? -10.28414 11.06315  -25.25734 1.000 19.21605 ? 69  HIS B CG  1 
ATOM   1663 N ND1 . HIS B 1 69  ? -11.40758 11.46913  -25.94354 1.000 17.43891 ? 69  HIS B ND1 1 
ATOM   1664 C CD2 . HIS B 1 69  ? -10.56004 11.24880  -23.94679 1.000 21.14937 ? 69  HIS B CD2 1 
ATOM   1665 C CE1 . HIS B 1 69  ? -12.32062 11.88440  -25.08917 1.000 18.04418 ? 69  HIS B CE1 1 
ATOM   1666 N NE2 . HIS B 1 69  ? -11.83235 11.76134  -23.87018 1.000 28.78684 ? 69  HIS B NE2 1 
ATOM   1667 N N   . ARG B 1 70  ? -6.69748  8.77981   -26.54758 1.000 15.77572 ? 70  ARG B N   1 
ATOM   1668 C CA  . ARG B 1 70  ? -5.69067  8.60994   -27.57474 1.000 20.73478 ? 70  ARG B CA  1 
ATOM   1669 C C   . ARG B 1 70  ? -6.22214  9.16466   -28.88701 1.000 19.31538 ? 70  ARG B C   1 
ATOM   1670 O O   . ARG B 1 70  ? -7.42323  9.38311   -29.04341 1.000 19.94616 ? 70  ARG B O   1 
ATOM   1671 C CB  . ARG B 1 70  ? -5.27683  7.14100   -27.71237 1.000 20.24383 ? 70  ARG B CB  1 
ATOM   1672 C CG  . ARG B 1 70  ? -6.39989  6.14608   -27.73846 1.000 16.73037 ? 70  ARG B CG  1 
ATOM   1673 C CD  . ARG B 1 70  ? -6.03783  4.90462   -26.96394 1.000 14.81440 ? 70  ARG B CD  1 
ATOM   1674 N NE  . ARG B 1 70  ? -7.23861  4.26881   -26.44343 1.000 22.96424 ? 70  ARG B NE  1 
ATOM   1675 C CZ  . ARG B 1 70  ? -7.99688  3.40810   -27.10702 1.000 22.53550 ? 70  ARG B CZ  1 
ATOM   1676 N NH1 . ARG B 1 70  ? -7.63239  2.92578   -28.28419 1.000 22.64192 ? 70  ARG B NH1 1 
ATOM   1677 N NH2 . ARG B 1 70  ? -9.15991  3.03659   -26.58346 1.000 23.45250 ? 70  ARG B NH2 1 
ATOM   1678 N N   . GLU B 1 71  ? -5.30630  9.40982   -29.82400 1.000 16.31793 ? 71  GLU B N   1 
ATOM   1679 C CA  . GLU B 1 71  ? -5.66061  10.02456  -31.09814 1.000 19.73646 ? 71  GLU B CA  1 
ATOM   1680 C C   . GLU B 1 71  ? -6.40012  9.03723   -31.98261 1.000 14.65803 ? 71  GLU B C   1 
ATOM   1681 O O   . GLU B 1 71  ? -6.50195  7.85355   -31.68409 1.000 19.93245 ? 71  GLU B O   1 
ATOM   1682 C CB  . GLU B 1 71  ? -4.42532  10.50327  -31.85563 1.000 22.34126 ? 71  GLU B CB  1 
ATOM   1683 C CG  . GLU B 1 71  ? -3.68988  11.68620  -31.25879 1.000 28.24693 ? 71  GLU B CG  1 
ATOM   1684 C CD  . GLU B 1 71  ? -2.28314  11.74345  -31.80840 1.000 20.28163 ? 71  GLU B CD  1 
ATOM   1685 O OE1 . GLU B 1 71  ? -1.90198  10.72858  -32.42445 1.000 17.78106 ? 71  GLU B OE1 1 
ATOM   1686 O OE2 . GLU B 1 71  ? -1.58148  12.77060  -31.63652 1.000 16.05277 ? 71  GLU B OE2 1 
ATOM   1687 N N   . GLY B 1 72  ? -6.90618  9.54619   -33.10022 1.000 21.15681 ? 72  GLY B N   1 
ATOM   1688 C CA  . GLY B 1 72  ? -7.54506  8.73675   -34.11335 1.000 15.50842 ? 72  GLY B CA  1 
ATOM   1689 C C   . GLY B 1 72  ? -9.03181  8.93911   -34.27409 1.000 20.37409 ? 72  GLY B C   1 
ATOM   1690 O O   . GLY B 1 72  ? -9.59871  8.36563   -35.20361 1.000 27.73064 ? 72  GLY B O   1 
ATOM   1691 N N   . ARG B 1 73  ? -9.69752  9.73218   -33.44073 1.000 21.93916 ? 73  ARG B N   1 
ATOM   1692 C CA  . ARG B 1 73  ? -11.14739 9.85735   -33.57080 1.000 23.41220 ? 73  ARG B CA  1 
ATOM   1693 C C   . ARG B 1 73  ? -11.51305 11.12932  -34.33099 1.000 15.93758 ? 73  ARG B C   1 
ATOM   1694 O O   . ARG B 1 73  ? -10.82131 12.14032  -34.26262 1.000 18.52978 ? 73  ARG B O   1 
ATOM   1695 C CB  . ARG B 1 73  ? -11.84261 9.83924   -32.19616 1.000 20.54561 ? 73  ARG B CB  1 
ATOM   1696 C CG  . ARG B 1 73  ? -11.60787 8.54467   -31.38167 1.000 19.21272 ? 73  ARG B CG  1 
ATOM   1697 C CD  . ARG B 1 73  ? -12.54739 8.36420   -30.19467 1.000 13.96083 ? 73  ARG B CD  1 
ATOM   1698 N NE  . ARG B 1 73  ? -12.41280 7.02655   -29.62117 1.000 19.77241 ? 73  ARG B NE  1 
ATOM   1699 C CZ  . ARG B 1 73  ? -11.53307 6.67544   -28.68993 1.000 22.27296 ? 73  ARG B CZ  1 
ATOM   1700 N NH1 . ARG B 1 73  ? -10.72206 7.56199   -28.13263 1.000 19.90360 ? 73  ARG B NH1 1 
ATOM   1701 N NH2 . ARG B 1 73  ? -11.46432 5.40087   -28.30776 1.000 20.58782 ? 73  ARG B NH2 1 
ATOM   1702 N N   . SER B 1 74  ? -12.63120 11.08549  -35.03406 1.000 17.61369 ? 74  SER B N   1 
ATOM   1703 C CA  . SER B 1 74  ? -13.04365 12.26551  -35.77754 1.000 20.40033 ? 74  SER B CA  1 
ATOM   1704 C C   . SER B 1 74  ? -13.52043 13.37116  -34.83479 1.000 20.09740 ? 74  SER B C   1 
ATOM   1705 O O   . SER B 1 74  ? -13.87526 13.14270  -33.67649 1.000 22.29265 ? 74  SER B O   1 
ATOM   1706 C CB  . SER B 1 74  ? -14.15247 11.93047  -36.77060 1.000 23.30461 ? 74  SER B CB  1 
ATOM   1707 O OG  . SER B 1 74  ? -15.39573 11.77335  -36.09927 1.000 28.35520 ? 74  SER B OG  1 
ATOM   1708 N N   . ALA B 1 75  ? -13.51795 14.58877  -35.36118 1.000 16.83510 ? 75  ALA B N   1 
ATOM   1709 C CA  . ALA B 1 75  ? -14.05250 15.71861  -34.62580 1.000 16.70244 ? 75  ALA B CA  1 
ATOM   1710 C C   . ALA B 1 75  ? -15.55438 15.56654  -34.41627 1.000 22.69774 ? 75  ALA B C   1 
ATOM   1711 O O   . ALA B 1 75  ? -16.08437 15.89965  -33.34491 1.000 22.28242 ? 75  ALA B O   1 
ATOM   1712 C CB  . ALA B 1 75  ? -13.72965 17.00613  -35.37511 1.000 16.21558 ? 75  ALA B CB  1 
ATOM   1713 N N   . ASP B 1 76  ? -16.25312 15.05994  -35.43055 1.000 22.09493 ? 76  ASP B N   1 
ATOM   1714 C CA  . ASP B 1 76  ? -17.65464 14.68226  -35.27875 1.000 17.55836 ? 76  ASP B CA  1 
ATOM   1715 C C   . ASP B 1 76  ? -17.86248 13.80540  -34.03906 1.000 20.78876 ? 76  ASP B C   1 
ATOM   1716 O O   . ASP B 1 76  ? -18.69382 14.10798  -33.17480 1.000 21.50192 ? 76  ASP B O   1 
ATOM   1717 C CB  . ASP B 1 76  ? -18.11328 13.96054  -36.54815 1.000 19.22877 ? 76  ASP B CB  1 
ATOM   1718 C CG  . ASP B 1 76  ? -19.60971 13.90537  -36.67038 1.000 24.19524 ? 76  ASP B CG  1 
ATOM   1719 O OD1 . ASP B 1 76  ? -20.28268 14.46539  -35.78251 1.000 17.17414 ? 76  ASP B OD1 1 
ATOM   1720 O OD2 . ASP B 1 76  ? -20.11031 13.30256  -37.65162 1.000 33.18496 ? 76  ASP B OD2 1 
ATOM   1721 N N   . LEU B 1 77  ? -17.09042 12.72324  -33.92218 1.000 19.24346 ? 77  LEU B N   1 
ATOM   1722 C CA  . LEU B 1 77  ? -17.26012 11.83333  -32.77885 1.000 20.74655 ? 77  LEU B CA  1 
ATOM   1723 C C   . LEU B 1 77  ? -16.95135 12.55791  -31.46989 1.000 19.23601 ? 77  LEU B C   1 
ATOM   1724 O O   . LEU B 1 77  ? -17.63327 12.35742  -30.45837 1.000 15.88765 ? 77  LEU B O   1 
ATOM   1725 C CB  . LEU B 1 77  ? -16.36763 10.60458  -32.95458 1.000 21.69811 ? 77  LEU B CB  1 
ATOM   1726 C CG  . LEU B 1 77  ? -16.46918 9.36096   -32.06748 1.000 22.42742 ? 77  LEU B CG  1 
ATOM   1727 C CD1 . LEU B 1 77  ? -16.07932 9.63237   -30.61227 1.000 23.48063 ? 77  LEU B CD1 1 
ATOM   1728 C CD2 . LEU B 1 77  ? -17.84849 8.72126   -32.15655 1.000 27.12643 ? 77  LEU B CD2 1 
ATOM   1729 N N   . LYS B 1 78  ? -15.92610 13.40664  -31.46899 1.000 23.12989 ? 78  LYS B N   1 
ATOM   1730 C CA  . LYS B 1 78  ? -15.51555 14.03015  -30.21516 1.000 20.80425 ? 78  LYS B CA  1 
ATOM   1731 C C   . LYS B 1 78  ? -16.52539 15.08067  -29.76852 1.000 20.93652 ? 78  LYS B C   1 
ATOM   1732 O O   . LYS B 1 78  ? -16.84002 15.17179  -28.57630 1.000 27.37142 ? 78  LYS B O   1 
ATOM   1733 C CB  . LYS B 1 78  ? -14.10862 14.61157  -30.35532 1.000 20.58030 ? 78  LYS B CB  1 
ATOM   1734 C CG  . LYS B 1 78  ? -13.01602 13.51320  -30.40276 1.000 17.50245 ? 78  LYS B CG  1 
ATOM   1735 C CD  . LYS B 1 78  ? -11.60665 14.09997  -30.55823 1.000 17.85607 ? 78  LYS B CD  1 
ATOM   1736 C CE  . LYS B 1 78  ? -11.44765 14.67795  -31.93771 1.000 18.30520 ? 78  LYS B CE  1 
ATOM   1737 N NZ  . LYS B 1 78  ? -10.06778 15.00237  -32.29941 1.000 18.13294 ? 78  LYS B NZ  1 
ATOM   1738 N N   . GLY B 1 79  ? -17.06501 15.85885  -30.71106 1.000 20.14842 ? 79  GLY B N   1 
ATOM   1739 C CA  . GLY B 1 79  ? -18.16704 16.74263  -30.38568 1.000 22.90908 ? 79  GLY B CA  1 
ATOM   1740 C C   . GLY B 1 79  ? -19.36864 16.02059  -29.79995 1.000 24.10692 ? 79  GLY B C   1 
ATOM   1741 O O   . GLY B 1 79  ? -20.12242 16.59579  -29.01244 1.000 24.99547 ? 79  GLY B O   1 
ATOM   1742 N N   . GLN B 1 80  ? -19.56604 14.75399  -30.15799 1.000 21.42197 ? 80  GLN B N   1 
ATOM   1743 C CA  . GLN B 1 80  ? -20.68909 14.03137  -29.57327 1.000 23.09796 ? 80  GLN B CA  1 
ATOM   1744 C C   . GLN B 1 80  ? -20.33236 13.41256  -28.22447 1.000 26.92915 ? 80  GLN B C   1 
ATOM   1745 O O   . GLN B 1 80  ? -21.17957 13.34841  -27.32198 1.000 22.61164 ? 80  GLN B O   1 
ATOM   1746 C CB  . GLN B 1 80  ? -21.17700 12.96653  -30.53517 1.000 18.63027 ? 80  GLN B CB  1 
ATOM   1747 C CG  . GLN B 1 80  ? -21.97896 13.51644  -31.67932 1.000 22.60213 ? 80  GLN B CG  1 
ATOM   1748 C CD  . GLN B 1 80  ? -22.89186 12.46603  -32.27357 1.000 33.21343 ? 80  GLN B CD  1 
ATOM   1749 O OE1 . GLN B 1 80  ? -22.80103 11.27060  -31.93905 1.000 36.18374 ? 80  GLN B OE1 1 
ATOM   1750 N NE2 . GLN B 1 80  ? -23.79146 12.90004  -33.14202 1.000 23.11107 ? 80  GLN B NE2 1 
ATOM   1751 N N   . LEU B 1 81  ? -19.08925 12.95126  -28.06195 1.000 26.26127 ? 81  LEU B N   1 
ATOM   1752 C CA  . LEU B 1 81  ? -18.67597 12.51410  -26.73756 1.000 32.13374 ? 81  LEU B CA  1 
ATOM   1753 C C   . LEU B 1 81  ? -18.77689 13.65210  -25.73174 1.000 26.75923 ? 81  LEU B C   1 
ATOM   1754 O O   . LEU B 1 81  ? -19.12176 13.42499  -24.56298 1.000 23.78229 ? 81  LEU B O   1 
ATOM   1755 C CB  . LEU B 1 81  ? -17.25267 11.95914  -26.77061 1.000 26.54514 ? 81  LEU B CB  1 
ATOM   1756 C CG  . LEU B 1 81  ? -16.87029 11.31902  -25.44001 1.000 22.99584 ? 81  LEU B CG  1 
ATOM   1757 C CD1 . LEU B 1 81  ? -17.95991 10.33693  -25.01915 1.000 22.87988 ? 81  LEU B CD1 1 
ATOM   1758 C CD2 . LEU B 1 81  ? -15.53842 10.62732  -25.57788 1.000 27.32000 ? 81  LEU B CD2 1 
ATOM   1759 N N   . ALA B 1 82  ? -18.51472 14.87685  -26.18203 1.000 19.41021 ? 82  ALA B N   1 
ATOM   1760 C CA  . ALA B 1 82  ? -18.41237 16.02316  -25.28980 1.000 24.94732 ? 82  ALA B CA  1 
ATOM   1761 C C   . ALA B 1 82  ? -19.78281 16.51087  -24.84857 1.000 27.67879 ? 82  ALA B C   1 
ATOM   1762 O O   . ALA B 1 82  ? -19.99781 16.77725  -23.65728 1.000 33.74144 ? 82  ALA B O   1 
ATOM   1763 C CB  . ALA B 1 82  ? -17.64000 17.15563  -25.97950 1.000 26.53857 ? 82  ALA B CB  1 
ATOM   1764 N N   . GLN B 1 83  ? -20.71834 16.63368  -25.80017 1.000 24.60736 ? 83  GLN B N   1 
ATOM   1765 C CA  . GLN B 1 83  ? -22.06711 17.09970  -25.48197 1.000 25.61934 ? 83  GLN B CA  1 
ATOM   1766 C C   . GLN B 1 83  ? -22.83045 16.09228  -24.63703 1.000 30.69973 ? 83  GLN B C   1 
ATOM   1767 O O   . GLN B 1 83  ? -23.61949 16.48352  -23.76640 1.000 28.87604 ? 83  GLN B O   1 
ATOM   1768 C CB  . GLN B 1 83  ? -22.85928 17.38415  -26.75055 1.000 27.25259 ? 83  GLN B CB  1 
ATOM   1769 C CG  . GLN B 1 83  ? -24.23978 17.92961  -26.44979 1.000 26.31035 ? 83  GLN B CG  1 
ATOM   1770 C CD  . GLN B 1 83  ? -24.18812 19.36862  -25.96098 1.000 37.12171 ? 83  GLN B CD  1 
ATOM   1771 O OE1 . GLN B 1 83  ? -24.61246 19.68394  -24.84172 1.000 34.15171 ? 83  GLN B OE1 1 
ATOM   1772 N NE2 . GLN B 1 83  ? -23.66394 20.25424  -26.80550 1.000 31.27871 ? 83  GLN B NE2 1 
ATOM   1773 N N   . ARG B 1 84  ? -22.63864 14.79226  -24.88914 1.000 27.31016 ? 84  ARG B N   1 
ATOM   1774 C CA  . ARG B 1 84  ? -23.32982 13.80838  -24.05739 1.000 28.19798 ? 84  ARG B CA  1 
ATOM   1775 C C   . ARG B 1 84  ? -22.81893 13.86179  -22.62828 1.000 28.68940 ? 84  ARG B C   1 
ATOM   1776 O O   . ARG B 1 84  ? -23.60177 13.73428  -21.68145 1.000 24.93565 ? 84  ARG B O   1 
ATOM   1777 C CB  . ARG B 1 84  ? -23.18990 12.39649  -24.62350 1.000 29.63380 ? 84  ARG B CB  1 
ATOM   1778 C CG  . ARG B 1 84  ? -23.92858 11.37226  -23.77601 1.000 34.02454 ? 84  ARG B CG  1 
ATOM   1779 C CD  . ARG B 1 84  ? -23.92263 9.96838   -24.35237 1.000 37.50093 ? 84  ARG B CD  1 
ATOM   1780 N NE  . ARG B 1 84  ? -24.07206 8.98679   -23.27979 1.000 41.07299 ? 84  ARG B NE  1 
ATOM   1781 C CZ  . ARG B 1 84  ? -24.55391 7.75808   -23.42451 1.000 37.82734 ? 84  ARG B CZ  1 
ATOM   1782 N NH1 . ARG B 1 84  ? -24.98665 7.31465   -24.59489 1.000 37.11228 ? 84  ARG B NH1 1 
ATOM   1783 N NH2 . ARG B 1 84  ? -24.61252 6.95666   -22.36345 1.000 36.41693 ? 84  ARG B NH2 1 
ATOM   1784 N N   . ILE B 1 85  ? -21.51523 14.10397  -22.45824 1.000 26.56849 ? 85  ILE B N   1 
ATOM   1785 C CA  . ILE B 1 85  ? -20.92986 14.25745  -21.12906 1.000 26.67320 ? 85  ILE B CA  1 
ATOM   1786 C C   . ILE B 1 85  ? -21.40080 15.56032  -20.46184 1.000 31.81879 ? 85  ILE B C   1 
ATOM   1787 O O   . ILE B 1 85  ? -21.56047 15.61244  -19.23759 1.000 31.40839 ? 85  ILE B O   1 
ATOM   1788 C CB  . ILE B 1 85  ? -19.39278 14.17146  -21.24381 1.000 30.49985 ? 85  ILE B CB  1 
ATOM   1789 C CG1 . ILE B 1 85  ? -18.93040 12.72240  -21.41280 1.000 30.54372 ? 85  ILE B CG1 1 
ATOM   1790 C CG2 . ILE B 1 85  ? -18.69735 14.81616  -20.06810 1.000 31.39714 ? 85  ILE B CG2 1 
ATOM   1791 C CD1 . ILE B 1 85  ? -17.48872 12.63044  -21.79945 1.000 14.80566 ? 85  ILE B CD1 1 
ATOM   1792 N N   . VAL B 1 86  ? -21.64392 16.62450  -21.23755 1.000 33.75983 ? 86  VAL B N   1 
ATOM   1793 C CA  . VAL B 1 86  ? -22.29519 17.80590  -20.66739 1.000 30.22455 ? 86  VAL B CA  1 
ATOM   1794 C C   . VAL B 1 86  ? -23.69929 17.46245  -20.18700 1.000 29.34198 ? 86  VAL B C   1 
ATOM   1795 O O   . VAL B 1 86  ? -24.12936 17.89141  -19.11249 1.000 32.62987 ? 86  VAL B O   1 
ATOM   1796 C CB  . VAL B 1 86  ? -22.32603 18.95685  -21.68927 1.000 30.10676 ? 86  VAL B CB  1 
ATOM   1797 C CG1 . VAL B 1 86  ? -23.38382 19.98964  -21.30633 1.000 28.40692 ? 86  VAL B CG1 1 
ATOM   1798 C CG2 . VAL B 1 86  ? -20.96173 19.61115  -21.78614 1.000 26.11141 ? 86  VAL B CG2 1 
ATOM   1799 N N   . ASP B 1 87  ? -24.42483 16.66468  -20.96401 1.000 30.19020 ? 87  ASP B N   1 
ATOM   1800 C CA  . ASP B 1 87  ? -25.84354 16.44828  -20.71392 1.000 29.16652 ? 87  ASP B CA  1 
ATOM   1801 C C   . ASP B 1 87  ? -26.09279 15.43098  -19.60255 1.000 37.54895 ? 87  ASP B C   1 
ATOM   1802 O O   . ASP B 1 87  ? -27.03353 15.59491  -18.81448 1.000 40.50480 ? 87  ASP B O   1 
ATOM   1803 C CB  . ASP B 1 87  ? -26.52340 16.00995  -22.01104 1.000 29.00159 ? 87  ASP B CB  1 
ATOM   1804 C CG  . ASP B 1 87  ? -26.60085 17.12818  -23.03629 1.000 32.99614 ? 87  ASP B CG  1 
ATOM   1805 O OD1 . ASP B 1 87  ? -26.23308 18.28597  -22.68864 1.000 34.39010 ? 87  ASP B OD1 1 
ATOM   1806 O OD2 . ASP B 1 87  ? -27.04343 16.85593  -24.17630 1.000 24.11294 ? 87  ASP B OD2 1 
ATOM   1807 N N   . ASP B 1 88  ? -25.27516 14.37586  -19.52560 1.000 29.86322 ? 88  ASP B N   1 
ATOM   1808 C CA  . ASP B 1 88  ? -25.46704 13.31538  -18.54138 1.000 31.25250 ? 88  ASP B CA  1 
ATOM   1809 C C   . ASP B 1 88  ? -24.83252 13.62891  -17.19581 1.000 34.47826 ? 88  ASP B C   1 
ATOM   1810 O O   . ASP B 1 88  ? -25.31249 13.14373  -16.16515 1.000 32.83811 ? 88  ASP B O   1 
ATOM   1811 C CB  . ASP B 1 88  ? -24.89042 11.98891  -19.05342 1.000 40.25432 ? 88  ASP B CB  1 
ATOM   1812 C CG  . ASP B 1 88  ? -25.70323 11.38577  -20.18881 1.000 37.24747 ? 88  ASP B CG  1 
ATOM   1813 O OD1 . ASP B 1 88  ? -26.38414 12.13649  -20.91435 1.000 46.00591 ? 88  ASP B OD1 1 
ATOM   1814 O OD2 . ASP B 1 88  ? -25.65434 10.15644  -20.35319 1.000 33.71129 ? 88  ASP B OD2 1 
ATOM   1815 N N   . VAL B 1 89  ? -23.74618 14.40278  -17.16609 1.000 35.26943 ? 89  VAL B N   1 
ATOM   1816 C CA  . VAL B 1 89  ? -23.21429 14.77962  -15.86277 1.000 32.64009 ? 89  VAL B CA  1 
ATOM   1817 C C   . VAL B 1 89  ? -24.08323 15.85819  -15.23933 1.000 28.73088 ? 89  VAL B C   1 
ATOM   1818 O O   . VAL B 1 89  ? -24.17834 15.95824  -14.01591 1.000 29.00300 ? 89  VAL B O   1 
ATOM   1819 C CB  . VAL B 1 89  ? -21.74056 15.20769  -15.97647 1.000 35.42366 ? 89  VAL B CB  1 
ATOM   1820 C CG1 . VAL B 1 89  ? -21.26833 15.87530  -14.69147 1.000 30.67688 ? 89  VAL B CG1 1 
ATOM   1821 C CG2 . VAL B 1 89  ? -20.86163 13.98928  -16.28329 1.000 32.32968 ? 89  VAL B CG2 1 
ATOM   1822 N N   . SER B 1 90  ? -24.74563 16.66888  -16.06183 1.000 35.30990 ? 90  SER B N   1 
ATOM   1823 C CA  . SER B 1 90  ? -25.73092 17.59026  -15.52065 1.000 35.77348 ? 90  SER B CA  1 
ATOM   1824 C C   . SER B 1 90  ? -26.78514 16.82996  -14.73129 1.000 37.48628 ? 90  SER B C   1 
ATOM   1825 O O   . SER B 1 90  ? -27.12765 17.22016  -13.61079 1.000 46.75385 ? 90  SER B O   1 
ATOM   1826 C CB  . SER B 1 90  ? -26.36766 18.40308  -16.64550 1.000 33.43358 ? 90  SER B CB  1 
ATOM   1827 O OG  . SER B 1 90  ? -27.52039 17.75855  -17.14549 1.000 32.56375 ? 90  SER B OG  1 
ATOM   1828 N N   . VAL B 1 91  ? -27.26132 15.70537  -15.27145 1.000 31.25862 ? 91  VAL B N   1 
ATOM   1829 C CA  . VAL B 1 91  ? -28.24861 14.89045  -14.57176 1.000 28.60807 ? 91  VAL B CA  1 
ATOM   1830 C C   . VAL B 1 91  ? -27.64069 14.24459  -13.33109 1.000 29.57769 ? 91  VAL B C   1 
ATOM   1831 O O   . VAL B 1 91  ? -28.13741 14.43145  -12.21484 1.000 33.11701 ? 91  VAL B O   1 
ATOM   1832 C CB  . VAL B 1 91  ? -28.84695 13.83161  -15.51034 1.000 27.57372 ? 91  VAL B CB  1 
ATOM   1833 C CG1 . VAL B 1 91  ? -29.57178 12.76240  -14.69645 1.000 27.41083 ? 91  VAL B CG1 1 
ATOM   1834 C CG2 . VAL B 1 91  ? -29.78757 14.48391  -16.51125 1.000 26.33168 ? 91  VAL B CG2 1 
ATOM   1835 N N   . ALA B 1 92  ? -26.57992 13.45209  -13.50388 1.000 24.21089 ? 92  ALA B N   1 
ATOM   1836 C CA  . ALA B 1 92  ? -26.08800 12.65271  -12.37593 1.000 31.38128 ? 92  ALA B CA  1 
ATOM   1837 C C   . ALA B 1 92  ? -25.55761 13.52432  -11.23625 1.000 32.32487 ? 92  ALA B C   1 
ATOM   1838 O O   . ALA B 1 92  ? -25.60479 13.12814  -10.06326 1.000 29.02282 ? 92  ALA B O   1 
ATOM   1839 C CB  . ALA B 1 92  ? -25.01121 11.67489  -12.84469 1.000 32.91845 ? 92  ALA B CB  1 
ATOM   1840 N N   . ALA B 1 93  ? -25.05102 14.70319  -11.55213 1.000 34.30848 ? 93  ALA B N   1 
ATOM   1841 C CA  . ALA B 1 93  ? -24.63503 15.63552  -10.52436 1.000 35.40148 ? 93  ALA B CA  1 
ATOM   1842 C C   . ALA B 1 93  ? -25.76895 16.54740  -10.07355 1.000 39.04534 ? 93  ALA B C   1 
ATOM   1843 O O   . ALA B 1 93  ? -25.64263 17.18246  -9.02776  1.000 33.31875 ? 93  ALA B O   1 
ATOM   1844 C CB  . ALA B 1 93  ? -23.45050 16.47222  -11.02791 1.000 31.55833 ? 93  ALA B CB  1 
ATOM   1845 N N   . GLU B 1 94  ? -26.88011 16.59981  -10.81603 1.000 37.35537 ? 94  GLU B N   1 
ATOM   1846 C CA  . GLU B 1 94  ? -27.98948 17.51923  -10.53350 1.000 39.65574 ? 94  GLU B CA  1 
ATOM   1847 C C   . GLU B 1 94  ? -27.51457 18.97522  -10.56990 1.000 40.19302 ? 94  GLU B C   1 
ATOM   1848 O O   . GLU B 1 94  ? -27.78528 19.76702  -9.65844  1.000 39.62373 ? 94  GLU B O   1 
ATOM   1849 C CB  . GLU B 1 94  ? -28.66350 17.19425  -9.19222  1.000 41.39077 ? 94  GLU B CB  1 
ATOM   1850 C CG  . GLU B 1 94  ? -28.71618 15.70756  -8.83653  1.000 44.31123 ? 94  GLU B CG  1 
ATOM   1851 C CD  . GLU B 1 94  ? -29.25563 15.43399  -7.43345  1.000 50.66057 ? 94  GLU B CD  1 
ATOM   1852 O OE1 . GLU B 1 94  ? -29.04957 16.28345  -6.52993  1.000 54.66770 ? 94  GLU B OE1 1 
ATOM   1853 O OE2 . GLU B 1 94  ? -29.88133 14.36417  -7.23546  1.000 50.99395 ? 94  GLU B OE2 1 
ATOM   1854 N N   . ILE B 1 95  ? -26.80887 19.33450  -11.64796 1.000 39.86728 ? 95  ILE B N   1 
ATOM   1855 C CA  . ILE B 1 95  ? -26.23099 20.66553  -11.78837 1.000 38.26066 ? 95  ILE B CA  1 
ATOM   1856 C C   . ILE B 1 95  ? -26.59552 21.24043  -13.15139 1.000 36.11475 ? 95  ILE B C   1 
ATOM   1857 O O   . ILE B 1 95  ? -26.72224 20.51148  -14.14143 1.000 41.81525 ? 95  ILE B O   1 
ATOM   1858 C CB  . ILE B 1 95  ? -24.69458 20.63214  -11.58955 1.000 36.69271 ? 95  ILE B CB  1 
ATOM   1859 C CG1 . ILE B 1 95  ? -24.07831 22.00877  -11.81954 1.000 35.96454 ? 95  ILE B CG1 1 
ATOM   1860 C CG2 . ILE B 1 95  ? -24.04562 19.59940  -12.49361 1.000 42.09051 ? 95  ILE B CG2 1 
ATOM   1861 C CD1 . ILE B 1 95  ? -23.24136 22.46754  -10.65664 1.000 33.93574 ? 95  ILE B CD1 1 
ATOM   1862 N N   . ASP B 1 96  ? -26.78454 22.56153  -13.19223 1.000 37.96264 ? 96  ASP B N   1 
ATOM   1863 C CA  . ASP B 1 96  ? -27.11287 23.24186  -14.43805 1.000 37.26962 ? 96  ASP B CA  1 
ATOM   1864 C C   . ASP B 1 96  ? -25.96025 23.11406  -15.43164 1.000 38.57351 ? 96  ASP B C   1 
ATOM   1865 O O   . ASP B 1 96  ? -24.79487 22.98084  -15.04931 1.000 39.98447 ? 96  ASP B O   1 
ATOM   1866 C CB  . ASP B 1 96  ? -27.41292 24.71200  -14.16284 1.000 42.60183 ? 96  ASP B CB  1 
ATOM   1867 C CG  . ASP B 1 96  ? -28.59551 25.24329  -14.95980 1.000 47.36349 ? 96  ASP B CG  1 
ATOM   1868 O OD1 . ASP B 1 96  ? -29.66355 25.50088  -14.35775 1.000 49.00989 ? 96  ASP B OD1 1 
ATOM   1869 O OD2 . ASP B 1 96  ? -28.44419 25.44321  -16.18314 1.000 54.69500 ? 96  ASP B OD2 1 
ATOM   1870 N N   . ARG B 1 97  ? -26.29383 23.14976  -16.72542 1.000 34.77333 ? 97  ARG B N   1 
ATOM   1871 C CA  . ARG B 1 97  ? -25.27221 22.96558  -17.75245 1.000 34.17494 ? 97  ARG B CA  1 
ATOM   1872 C C   . ARG B 1 97  ? -24.27313 24.11881  -17.77559 1.000 32.97013 ? 97  ARG B C   1 
ATOM   1873 O O   . ARG B 1 97  ? -23.09321 23.90243  -18.06932 1.000 28.09839 ? 97  ARG B O   1 
ATOM   1874 C CB  . ARG B 1 97  ? -25.91547 22.79953  -19.13425 1.000 32.67268 ? 97  ARG B CB  1 
ATOM   1875 C CG  . ARG B 1 97  ? -26.66846 21.48843  -19.35379 1.000 36.38037 ? 97  ARG B CG  1 
ATOM   1876 C CD  . ARG B 1 97  ? -27.15215 21.35197  -20.79969 1.000 35.05660 ? 97  ARG B CD  1 
ATOM   1877 N NE  . ARG B 1 97  ? -28.60520 21.40596  -20.89837 1.000 38.77848 ? 97  ARG B NE  1 
ATOM   1878 C CZ  . ARG B 1 97  ? -29.39305 20.34329  -21.00022 1.000 39.49985 ? 97  ARG B CZ  1 
ATOM   1879 N NH1 . ARG B 1 97  ? -28.89947 19.11686  -21.04285 1.000 40.89020 ? 97  ARG B NH1 1 
ATOM   1880 N NH2 . ARG B 1 97  ? -30.70940 20.51573  -21.07094 1.000 43.56952 ? 97  ARG B NH2 1 
ATOM   1881 N N   . LYS B 1 98  ? -24.71313 25.34117  -17.45513 1.000 31.80263 ? 98  LYS B N   1 
ATOM   1882 C CA  . LYS B 1 98  ? -23.84690 26.50716  -17.60278 1.000 28.26443 ? 98  LYS B CA  1 
ATOM   1883 C C   . LYS B 1 98  ? -22.58818 26.40302  -16.74409 1.000 29.47392 ? 98  LYS B C   1 
ATOM   1884 O O   . LYS B 1 98  ? -21.62101 27.13361  -16.98884 1.000 24.00061 ? 98  LYS B O   1 
ATOM   1885 C CB  . LYS B 1 98  ? -24.63252 27.78376  -17.28173 1.000 23.43595 ? 98  LYS B CB  1 
ATOM   1886 C CG  . LYS B 1 98  ? -25.19360 27.85774  -15.85116 1.000 36.65200 ? 98  LYS B CG  1 
ATOM   1887 C CD  . LYS B 1 98  ? -26.68004 28.24841  -15.81643 1.000 43.98847 ? 98  LYS B CD  1 
ATOM   1888 C CE  . LYS B 1 98  ? -27.24949 28.14479  -14.39769 1.000 46.41063 ? 98  LYS B CE  1 
ATOM   1889 N NZ  . LYS B 1 98  ? -28.65891 28.60509  -14.28815 1.000 39.05201 ? 98  LYS B NZ  1 
ATOM   1890 N N   . HIS B 1 99  ? -22.57225 25.48751  -15.77113 1.000 31.22173 ? 99  HIS B N   1 
ATOM   1891 C CA  . HIS B 1 99  ? -21.44355 25.27307  -14.87589 1.000 33.18582 ? 99  HIS B CA  1 
ATOM   1892 C C   . HIS B 1 99  ? -20.51020 24.15862  -15.33039 1.000 30.52352 ? 99  HIS B C   1 
ATOM   1893 O O   . HIS B 1 99  ? -19.61517 23.78499  -14.56805 1.000 25.62290 ? 99  HIS B O   1 
ATOM   1894 C CB  . HIS B 1 99  ? -21.93466 24.94700  -13.45476 1.000 30.49553 ? 99  HIS B CB  1 
ATOM   1895 C CG  . HIS B 1 99  ? -22.46416 26.13170  -12.70798 1.000 33.29180 ? 99  HIS B CG  1 
ATOM   1896 N ND1 . HIS B 1 99  ? -23.80745 26.43692  -12.65201 1.000 37.53190 ? 99  HIS B ND1 1 
ATOM   1897 C CD2 . HIS B 1 99  ? -21.83050 27.09926  -12.00431 1.000 32.60378 ? 99  HIS B CD2 1 
ATOM   1898 C CE1 . HIS B 1 99  ? -23.97938 27.52990  -11.92997 1.000 34.43876 ? 99  HIS B CE1 1 
ATOM   1899 N NE2 . HIS B 1 99  ? -22.79714 27.94920  -11.52066 1.000 30.09861 ? 99  HIS B NE2 1 
ATOM   1900 N N   . ILE B 1 100 ? -20.68713 23.60961  -16.53194 1.000 29.70861 ? 100 ILE B N   1 
ATOM   1901 C CA  . ILE B 1 100 ? -19.89608 22.46319  -16.97236 1.000 28.49810 ? 100 ILE B CA  1 
ATOM   1902 C C   . ILE B 1 100 ? -18.88871 22.90764  -18.02622 1.000 22.85289 ? 100 ILE B C   1 
ATOM   1903 O O   . ILE B 1 100 ? -19.23990 23.57145  -19.00960 1.000 28.22884 ? 100 ILE B O   1 
ATOM   1904 C CB  . ILE B 1 100 ? -20.77302 21.29426  -17.47029 1.000 33.75305 ? 100 ILE B CB  1 
ATOM   1905 C CG1 . ILE B 1 100 ? -19.92713 20.02916  -17.58033 1.000 28.93858 ? 100 ILE B CG1 1 
ATOM   1906 C CG2 . ILE B 1 100 ? -21.39470 21.56103  -18.82600 1.000 33.25291 ? 100 ILE B CG2 1 
ATOM   1907 C CD1 . ILE B 1 100 ? -18.99277 19.85736  -16.43400 1.000 23.55258 ? 100 ILE B CD1 1 
ATOM   1908 N N   . TRP B 1 101 ? -17.62379 22.56571  -17.78622 1.000 33.67778 ? 101 TRP B N   1 
ATOM   1909 C CA  . TRP B 1 101 ? -16.52350 22.75511  -18.72268 1.000 24.62991 ? 101 TRP B CA  1 
ATOM   1910 C C   . TRP B 1 101 ? -15.99307 21.37534  -19.07170 1.000 23.00086 ? 101 TRP B C   1 
ATOM   1911 O O   . TRP B 1 101 ? -15.71095 20.57990  -18.16810 1.000 27.80939 ? 101 TRP B O   1 
ATOM   1912 C CB  . TRP B 1 101 ? -15.40845 23.63430  -18.11288 1.000 24.11102 ? 101 TRP B CB  1 
ATOM   1913 C CG  . TRP B 1 101 ? -15.80479 25.06733  -17.85908 1.000 22.64413 ? 101 TRP B CG  1 
ATOM   1914 C CD1 . TRP B 1 101 ? -16.99292 25.50773  -17.35601 1.000 29.80323 ? 101 TRP B CD1 1 
ATOM   1915 C CD2 . TRP B 1 101 ? -15.02535 26.24711  -18.12169 1.000 22.12255 ? 101 TRP B CD2 1 
ATOM   1916 N NE1 . TRP B 1 101 ? -16.99314 26.87855  -17.26729 1.000 29.52973 ? 101 TRP B NE1 1 
ATOM   1917 C CE2 . TRP B 1 101 ? -15.79627 27.35486  -17.73172 1.000 22.37600 ? 101 TRP B CE2 1 
ATOM   1918 C CE3 . TRP B 1 101 ? -13.74172 26.47094  -18.61643 1.000 22.39372 ? 101 TRP B CE3 1 
ATOM   1919 C CZ2 . TRP B 1 101 ? -15.33071 28.66030  -17.84075 1.000 26.39981 ? 101 TRP B CZ2 1 
ATOM   1920 C CZ3 . TRP B 1 101 ? -13.28208 27.76300  -18.72107 1.000 22.45000 ? 101 TRP B CZ3 1 
ATOM   1921 C CH2 . TRP B 1 101 ? -14.07483 28.84381  -18.34932 1.000 22.93560 ? 101 TRP B CH2 1 
ATOM   1922 N N   . VAL B 1 102 ? -15.90353 21.06558  -20.36658 1.000 22.94200 ? 102 VAL B N   1 
ATOM   1923 C CA  . VAL B 1 102 ? -15.39595 19.77126  -20.82869 1.000 19.52018 ? 102 VAL B CA  1 
ATOM   1924 C C   . VAL B 1 102 ? -14.31343 20.01268  -21.86923 1.000 25.30941 ? 102 VAL B C   1 
ATOM   1925 O O   . VAL B 1 102 ? -14.60066 20.48644  -22.98206 1.000 14.23747 ? 102 VAL B O   1 
ATOM   1926 C CB  . VAL B 1 102 ? -16.49092 18.86546  -21.41590 1.000 27.70948 ? 102 VAL B CB  1 
ATOM   1927 C CG1 . VAL B 1 102 ? -15.84312 17.67699  -22.17717 1.000 14.10245 ? 102 VAL B CG1 1 
ATOM   1928 C CG2 . VAL B 1 102 ? -17.43556 18.36927  -20.33247 1.000 20.48748 ? 102 VAL B CG2 1 
ATOM   1929 N N   . PHE B 1 103 ? -13.07904 19.64412  -21.52823 1.000 24.73131 ? 103 PHE B N   1 
ATOM   1930 C CA  . PHE B 1 103 ? -11.93684 19.72259  -22.42840 1.000 16.04104 ? 103 PHE B CA  1 
ATOM   1931 C C   . PHE B 1 103 ? -11.40956 18.31386  -22.67181 1.000 19.87109 ? 103 PHE B C   1 
ATOM   1932 O O   . PHE B 1 103 ? -11.37279 17.49452  -21.74552 1.000 16.97609 ? 103 PHE B O   1 
ATOM   1933 C CB  . PHE B 1 103 ? -10.79644 20.58917  -21.84765 1.000 21.60610 ? 103 PHE B CB  1 
ATOM   1934 C CG  . PHE B 1 103 ? -11.10558 22.07142  -21.70787 1.000 21.01103 ? 103 PHE B CG  1 
ATOM   1935 C CD1 . PHE B 1 103 ? -12.38592 22.57783  -21.86491 1.000 18.77510 ? 103 PHE B CD1 1 
ATOM   1936 C CD2 . PHE B 1 103 ? -10.07503 22.95843  -21.38816 1.000 23.29960 ? 103 PHE B CD2 1 
ATOM   1937 C CE1 . PHE B 1 103 ? -12.63474 23.94303  -21.70992 1.000 24.57402 ? 103 PHE B CE1 1 
ATOM   1938 C CE2 . PHE B 1 103 ? -10.30830 24.31762  -21.24913 1.000 19.45137 ? 103 PHE B CE2 1 
ATOM   1939 C CZ  . PHE B 1 103 ? -11.59072 24.81120  -21.39903 1.000 21.71736 ? 103 PHE B CZ  1 
ATOM   1940 N N   . PHE B 1 104 ? -10.97341 18.04320  -23.90987 1.000 19.87494 ? 104 PHE B N   1 
ATOM   1941 C CA  . PHE B 1 104 ? -10.39617 16.75705  -24.30651 1.000 18.41594 ? 104 PHE B CA  1 
ATOM   1942 C C   . PHE B 1 104 ? -9.00648  16.94769  -24.90269 1.000 21.47570 ? 104 PHE B C   1 
ATOM   1943 O O   . PHE B 1 104 ? -8.84509  17.69140  -25.87713 1.000 20.39679 ? 104 PHE B O   1 
ATOM   1944 C CB  . PHE B 1 104 ? -11.24401 16.03705  -25.35562 1.000 24.46662 ? 104 PHE B CB  1 
ATOM   1945 C CG  . PHE B 1 104 ? -12.55063 15.55279  -24.85920 1.000 22.54786 ? 104 PHE B CG  1 
ATOM   1946 C CD1 . PHE B 1 104 ? -12.73827 15.28086  -23.52244 1.000 21.16981 ? 104 PHE B CD1 1 
ATOM   1947 C CD2 . PHE B 1 104 ? -13.59946 15.35894  -25.74590 1.000 22.78598 ? 104 PHE B CD2 1 
ATOM   1948 C CE1 . PHE B 1 104 ? -13.95632 14.82270  -23.07830 1.000 26.65010 ? 104 PHE B CE1 1 
ATOM   1949 C CE2 . PHE B 1 104 ? -14.81638 14.90613  -25.31519 1.000 24.84669 ? 104 PHE B CE2 1 
ATOM   1950 C CZ  . PHE B 1 104 ? -15.00562 14.63901  -23.98415 1.000 22.15760 ? 104 PHE B CZ  1 
ATOM   1951 N N   . GLY B 1 105 ? -8.02372  16.25021  -24.33824 1.000 16.32094 ? 105 GLY B N   1 
ATOM   1952 C CA  . GLY B 1 105 ? -6.71471  16.10630  -24.93803 1.000 12.83310 ? 105 GLY B CA  1 
ATOM   1953 C C   . GLY B 1 105 ? -6.56474  14.72934  -25.55895 1.000 16.34829 ? 105 GLY B C   1 
ATOM   1954 O O   . GLY B 1 105 ? -7.24680  13.78394  -25.17707 1.000 18.78448 ? 105 GLY B O   1 
ATOM   1955 N N   . GLU B 1 106 ? -5.66905  14.62872  -26.54198 1.000 20.21440 ? 106 GLU B N   1 
ATOM   1956 C CA  . GLU B 1 106 ? -5.41251  13.38910  -27.26937 1.000 19.28903 ? 106 GLU B CA  1 
ATOM   1957 C C   . GLU B 1 106 ? -3.90999  13.18120  -27.38633 1.000 17.52855 ? 106 GLU B C   1 
ATOM   1958 O O   . GLU B 1 106 ? -3.15011  14.14901  -27.47573 1.000 15.92476 ? 106 GLU B O   1 
ATOM   1959 C CB  . GLU B 1 106 ? -6.04091  13.39365  -28.68795 1.000 14.40708 ? 106 GLU B CB  1 
ATOM   1960 C CG  . GLU B 1 106 ? -7.42387  13.97742  -28.74898 1.000 16.74682 ? 106 GLU B CG  1 
ATOM   1961 C CD  . GLU B 1 106 ? -7.89554  14.19310  -30.15731 1.000 22.59933 ? 106 GLU B CD  1 
ATOM   1962 O OE1 . GLU B 1 106 ? -8.19455  13.18790  -30.84671 1.000 19.56996 ? 106 GLU B OE1 1 
ATOM   1963 O OE2 . GLU B 1 106 ? -7.94823  15.37254  -30.57410 1.000 18.31249 ? 106 GLU B OE2 1 
ATOM   1964 N N   . MET B 1 107 ? -3.49456  11.91183  -27.40707 1.000 15.02667 ? 107 MET B N   1 
ATOM   1965 C CA  . MET B 1 107 ? -2.08753  11.53042  -27.46960 1.000 20.36663 ? 107 MET B CA  1 
ATOM   1966 C C   . MET B 1 107 ? -1.95826  10.25193  -28.28742 1.000 23.68066 ? 107 MET B C   1 
ATOM   1967 O O   . MET B 1 107 ? -2.90641  9.46202   -28.35239 1.000 22.96181 ? 107 MET B O   1 
ATOM   1968 C CB  . MET B 1 107 ? -1.49396  11.30351  -26.06807 1.000 16.93858 ? 107 MET B CB  1 
ATOM   1969 C CG  . MET B 1 107 ? -1.42349  12.54817  -25.14222 1.000 16.98124 ? 107 MET B CG  1 
ATOM   1970 S SD  . MET B 1 107 ? -1.58061  12.20908  -23.33089 1.000 16.75085 ? 107 MET B SD  1 
ATOM   1971 C CE  . MET B 1 107 ? -3.20871  11.43072  -23.28293 1.000 18.60045 ? 107 MET B CE  1 
ATOM   1972 N N   . PRO B 1 108 ? -0.80490  10.00195  -28.89194 1.000 22.00330 ? 108 PRO B N   1 
ATOM   1973 C CA  . PRO B 1 108 ? -0.58914  8.69085   -29.51808 1.000 22.48330 ? 108 PRO B CA  1 
ATOM   1974 C C   . PRO B 1 108 ? -0.70242  7.57024   -28.49079 1.000 20.30650 ? 108 PRO B C   1 
ATOM   1975 O O   . PRO B 1 108 ? -0.20760  7.68115   -27.36668 1.000 17.87498 ? 108 PRO B O   1 
ATOM   1976 C CB  . PRO B 1 108 ? 0.82971   8.79911   -30.08591 1.000 21.57192 ? 108 PRO B CB  1 
ATOM   1977 C CG  . PRO B 1 108 ? 1.02560   10.29332  -30.28830 1.000 16.81062 ? 108 PRO B CG  1 
ATOM   1978 C CD  . PRO B 1 108 ? 0.32925   10.91374  -29.10866 1.000 21.77343 ? 108 PRO B CD  1 
ATOM   1979 N N   . ALA B 1 109 ? -1.38598  6.49016   -28.87905 1.000 15.88407 ? 109 ALA B N   1 
ATOM   1980 C CA  . ALA B 1 109 ? -1.56162  5.38335   -27.94804 1.000 20.19111 ? 109 ALA B CA  1 
ATOM   1981 C C   . ALA B 1 109 ? -0.22564  4.83610   -27.47203 1.000 20.47797 ? 109 ALA B C   1 
ATOM   1982 O O   . ALA B 1 109 ? -0.11876  4.40416   -26.32113 1.000 22.16561 ? 109 ALA B O   1 
ATOM   1983 C CB  . ALA B 1 109 ? -2.39111  4.26017   -28.57297 1.000 19.97706 ? 109 ALA B CB  1 
ATOM   1984 N N   . GLN B 1 110 ? 0.80039   4.86371   -28.33423 1.000 18.57714 ? 110 GLN B N   1 
ATOM   1985 C CA  . GLN B 1 110 ? 2.12755   4.33749   -28.03230 1.000 19.63676 ? 110 GLN B CA  1 
ATOM   1986 C C   . GLN B 1 110 ? 2.81418   5.04029   -26.86867 1.000 17.84247 ? 110 GLN B C   1 
ATOM   1987 O O   . GLN B 1 110 ? 3.84175   4.54272   -26.40907 1.000 13.67680 ? 110 GLN B O   1 
ATOM   1988 C CB  . GLN B 1 110 ? 3.04585   4.43142   -29.26462 1.000 29.99841 ? 110 GLN B CB  1 
ATOM   1989 C CG  . GLN B 1 110 ? 2.76836   3.41144   -30.35693 1.000 18.93304 ? 110 GLN B CG  1 
ATOM   1990 C CD  . GLN B 1 110 ? 1.53152   3.76096   -31.13126 1.000 36.00999 ? 110 GLN B CD  1 
ATOM   1991 O OE1 . GLN B 1 110 ? 1.36287   4.89729   -31.58267 1.000 38.32743 ? 110 GLN B OE1 1 
ATOM   1992 N NE2 . GLN B 1 110 ? 0.63710   2.78948   -31.27869 1.000 47.55949 ? 110 GLN B NE2 1 
ATOM   1993 N N   . GLN B 1 111 ? 2.33761   6.20238   -26.42494 1.000 14.05135 ? 111 GLN B N   1 
ATOM   1994 C CA  . GLN B 1 111 ? 2.80388   6.76567   -25.16222 1.000 13.93018 ? 111 GLN B CA  1 
ATOM   1995 C C   . GLN B 1 111 ? 1.65645   6.83391   -24.14456 1.000 14.25789 ? 111 GLN B C   1 
ATOM   1996 O O   . GLN B 1 111 ? 1.55172   7.77333   -23.33584 1.000 10.53874 ? 111 GLN B O   1 
ATOM   1997 C CB  . GLN B 1 111 ? 3.46724   8.12566   -25.38716 1.000 18.23311 ? 111 GLN B CB  1 
ATOM   1998 C CG  . GLN B 1 111 ? 2.51672   9.25072   -25.77990 1.000 20.83932 ? 111 GLN B CG  1 
ATOM   1999 C CD  . GLN B 1 111 ? 3.18693   10.28886  -26.63155 1.000 24.34941 ? 111 GLN B CD  1 
ATOM   2000 O OE1 . GLN B 1 111 ? 4.07153   9.96112   -27.41387 1.000 23.02721 ? 111 GLN B OE1 1 
ATOM   2001 N NE2 . GLN B 1 111 ? 2.78705   11.55265  -26.47623 1.000 21.58194 ? 111 GLN B NE2 1 
ATOM   2002 N N   . MET B 1 112 ? 0.78141   5.81789   -24.17416 1.000 12.48706 ? 112 MET B N   1 
ATOM   2003 C CA  . MET B 1 112 ? -0.36295  5.74183   -23.26294 1.000 17.30509 ? 112 MET B CA  1 
ATOM   2004 C C   . MET B 1 112 ? -0.43985  4.34780   -22.64007 1.000 19.16764 ? 112 MET B C   1 
ATOM   2005 O O   . MET B 1 112 ? -0.41885  3.33741   -23.35411 1.000 14.49702 ? 112 MET B O   1 
ATOM   2006 C CB  . MET B 1 112 ? -1.68379  6.10167   -23.98539 1.000 18.75579 ? 112 MET B CB  1 
ATOM   2007 C CG  . MET B 1 112 ? -1.85228  7.62092   -24.29770 1.000 13.50192 ? 112 MET B CG  1 
ATOM   2008 S SD  . MET B 1 112 ? -3.41827  8.14728   -25.06017 1.000 12.89254 ? 112 MET B SD  1 
ATOM   2009 C CE  . MET B 1 112 ? -4.57877  7.88696   -23.72813 1.000 16.02654 ? 112 MET B CE  1 
ATOM   2010 N N   . VAL B 1 113 ? -0.54252  4.29424   -21.30946 1.000 15.95441 ? 113 VAL B N   1 
ATOM   2011 C CA  . VAL B 1 113 ? -0.46176  3.04306   -20.55565 1.000 20.28212 ? 113 VAL B CA  1 
ATOM   2012 C C   . VAL B 1 113 ? -1.59264  2.97653   -19.53240 1.000 20.09206 ? 113 VAL B C   1 
ATOM   2013 O O   . VAL B 1 113 ? -1.79754  3.91811   -18.75336 1.000 17.60078 ? 113 VAL B O   1 
ATOM   2014 C CB  . VAL B 1 113 ? 0.90891   2.87972   -19.86484 1.000 16.16528 ? 113 VAL B CB  1 
ATOM   2015 C CG1 . VAL B 1 113 ? 0.93384   1.61282   -19.02830 1.000 19.52804 ? 113 VAL B CG1 1 
ATOM   2016 C CG2 . VAL B 1 113 ? 2.01718   2.86490   -20.91254 1.000 17.63641 ? 113 VAL B CG2 1 
ATOM   2017 N N   . GLU B 1 114 ? -2.33007  1.86658   -19.55691 1.000 17.78956 ? 114 GLU B N   1 
ATOM   2018 C CA  . GLU B 1 114 ? -3.34973  1.52493   -18.57349 1.000 23.02960 ? 114 GLU B CA  1 
ATOM   2019 C C   . GLU B 1 114 ? -3.15165  0.07617   -18.14236 1.000 17.88244 ? 114 GLU B C   1 
ATOM   2020 O O   . GLU B 1 114 ? -2.78589  -0.77708  -18.95329 1.000 21.90589 ? 114 GLU B O   1 
ATOM   2021 C CB  . GLU B 1 114 ? -4.75310  1.73963   -19.14906 1.000 18.98995 ? 114 GLU B CB  1 
ATOM   2022 C CG  . GLU B 1 114 ? -4.90537  3.13114   -19.69597 1.000 24.35363 ? 114 GLU B CG  1 
ATOM   2023 C CD  . GLU B 1 114 ? -6.29128  3.43364   -20.20075 1.000 21.36941 ? 114 GLU B CD  1 
ATOM   2024 O OE1 . GLU B 1 114 ? -7.20550  2.65985   -19.88172 1.000 20.74529 ? 114 GLU B OE1 1 
ATOM   2025 O OE2 . GLU B 1 114 ? -6.45060  4.45059   -20.90484 1.000 21.54354 ? 114 GLU B OE2 1 
ATOM   2026 N N   . TYR B 1 115 ? -3.35526  -0.19342  -16.85855 1.000 22.53497 ? 115 TYR B N   1 
ATOM   2027 C CA  . TYR B 1 115 ? -3.13663  -1.53537  -16.30412 1.000 22.34448 ? 115 TYR B CA  1 
ATOM   2028 C C   . TYR B 1 115 ? -1.72072  -2.02599  -16.57904 1.000 27.31581 ? 115 TYR B C   1 
ATOM   2029 O O   . TYR B 1 115 ? -1.48483  -3.23036  -16.71417 1.000 27.89990 ? 115 TYR B O   1 
ATOM   2030 C CB  . TYR B 1 115 ? -4.16096  -2.53135  -16.84600 1.000 15.71989 ? 115 TYR B CB  1 
ATOM   2031 C CG  . TYR B 1 115 ? -5.55754  -2.22377  -16.38545 1.000 22.82063 ? 115 TYR B CG  1 
ATOM   2032 C CD1 . TYR B 1 115 ? -6.00332  -2.62837  -15.12329 1.000 24.75765 ? 115 TYR B CD1 1 
ATOM   2033 C CD2 . TYR B 1 115 ? -6.43706  -1.51226  -17.19485 1.000 19.15998 ? 115 TYR B CD2 1 
ATOM   2034 C CE1 . TYR B 1 115 ? -7.29371  -2.33896  -14.69627 1.000 29.76169 ? 115 TYR B CE1 1 
ATOM   2035 C CE2 . TYR B 1 115 ? -7.72835  -1.23532  -16.77443 1.000 24.74628 ? 115 TYR B CE2 1 
ATOM   2036 C CZ  . TYR B 1 115 ? -8.14962  -1.64483  -15.53439 1.000 20.26049 ? 115 TYR B CZ  1 
ATOM   2037 O OH  . TYR B 1 115 ? -9.41790  -1.34782  -15.12414 1.000 25.50427 ? 115 TYR B OH  1 
ATOM   2038 N N   . GLY B 1 116 ? -0.77666  -1.09110  -16.67680 1.000 23.77988 ? 116 GLY B N   1 
ATOM   2039 C CA  . GLY B 1 116 ? 0.59542   -1.43861  -16.98024 1.000 24.97700 ? 116 GLY B CA  1 
ATOM   2040 C C   . GLY B 1 116 ? 0.83963   -1.89908  -18.39889 1.000 23.42179 ? 116 GLY B C   1 
ATOM   2041 O O   . GLY B 1 116 ? 1.87253   -2.50638  -18.66619 1.000 18.85700 ? 116 GLY B O   1 
ATOM   2042 N N   . ARG B 1 117 ? -0.08419  -1.63116  -19.32141 1.000 24.12458 ? 117 ARG B N   1 
ATOM   2043 C CA  . ARG B 1 117 ? 0.06381   -2.04061  -20.71234 1.000 22.21205 ? 117 ARG B CA  1 
ATOM   2044 C C   . ARG B 1 117 ? -0.10519  -0.83380  -21.62834 1.000 21.33025 ? 117 ARG B C   1 
ATOM   2045 O O   . ARG B 1 117 ? -0.82729  0.11024   -21.31018 1.000 19.78710 ? 117 ARG B O   1 
ATOM   2046 C CB  . ARG B 1 117 ? -0.95340  -3.12525  -21.10229 1.000 23.32824 ? 117 ARG B CB  1 
ATOM   2047 C CG  . ARG B 1 117 ? -0.93057  -4.35741  -20.21222 1.000 19.96272 ? 117 ARG B CG  1 
ATOM   2048 C CD  . ARG B 1 117 ? 0.40044   -5.08584  -20.32098 1.000 23.63729 ? 117 ARG B CD  1 
ATOM   2049 N NE  . ARG B 1 117 ? 0.59038   -5.70534  -21.62386 1.000 31.73404 ? 117 ARG B NE  1 
ATOM   2050 C CZ  . ARG B 1 117 ? 0.96884   -6.96311  -21.79545 1.000 39.47344 ? 117 ARG B CZ  1 
ATOM   2051 N NH1 . ARG B 1 117 ? 1.21377   -7.75237  -20.75962 1.000 36.85708 ? 117 ARG B NH1 1 
ATOM   2052 N NH2 . ARG B 1 117 ? 1.12226   -7.43281  -23.03381 1.000 23.46900 ? 117 ARG B NH2 1 
ATOM   2053 N N   . PHE B 1 118 ? 0.55757   -0.87663  -22.77928 1.000 16.94118 ? 118 PHE B N   1 
ATOM   2054 C CA  . PHE B 1 118 ? 0.34739   0.16625   -23.76730 1.000 19.35715 ? 118 PHE B CA  1 
ATOM   2055 C C   . PHE B 1 118 ? -0.98283  -0.03864  -24.47125 1.000 20.11140 ? 118 PHE B C   1 
ATOM   2056 O O   . PHE B 1 118 ? -1.40688  -1.16982  -24.73456 1.000 17.77670 ? 118 PHE B O   1 
ATOM   2057 C CB  . PHE B 1 118 ? 1.48732   0.19623   -24.78284 1.000 21.33795 ? 118 PHE B CB  1 
ATOM   2058 C CG  . PHE B 1 118 ? 2.76625   0.72313   -24.21749 1.000 18.38219 ? 118 PHE B CG  1 
ATOM   2059 C CD1 . PHE B 1 118 ? 3.66144   -0.12548  -23.58812 1.000 17.31676 ? 118 PHE B CD1 1 
ATOM   2060 C CD2 . PHE B 1 118 ? 3.05509   2.06818   -24.28186 1.000 17.83864 ? 118 PHE B CD2 1 
ATOM   2061 C CE1 . PHE B 1 118 ? 4.83853   0.35517   -23.04956 1.000 19.93226 ? 118 PHE B CE1 1 
ATOM   2062 C CE2 . PHE B 1 118 ? 4.23626   2.57085   -23.75597 1.000 14.10732 ? 118 PHE B CE2 1 
ATOM   2063 C CZ  . PHE B 1 118 ? 5.13972   1.70723   -23.14954 1.000 18.87750 ? 118 PHE B CZ  1 
ATOM   2064 N N   . LEU B 1 119 ? -1.63815  1.06502   -24.78615 1.000 21.48089 ? 119 LEU B N   1 
ATOM   2065 C CA  . LEU B 1 119 ? -2.95908  0.96148   -25.35386 1.000 19.21368 ? 119 LEU B CA  1 
ATOM   2066 C C   . LEU B 1 119 ? -2.87800  0.62143   -26.83458 1.000 18.55111 ? 119 LEU B C   1 
ATOM   2067 O O   . LEU B 1 119 ? -1.82061  0.72899   -27.45943 1.000 18.86642 ? 119 LEU B O   1 
ATOM   2068 C CB  . LEU B 1 119 ? -3.71947  2.26297   -25.12975 1.000 18.50633 ? 119 LEU B CB  1 
ATOM   2069 C CG  . LEU B 1 119 ? -4.28425  2.46205   -23.72797 1.000 13.49566 ? 119 LEU B CG  1 
ATOM   2070 C CD1 . LEU B 1 119 ? -5.23065  3.63753   -23.71193 1.000 17.00432 ? 119 LEU B CD1 1 
ATOM   2071 C CD2 . LEU B 1 119 ? -4.96298  1.21517   -23.22460 1.000 18.63865 ? 119 LEU B CD2 1 
ATOM   2072 N N   . PRO B 1 120 ? -3.96603  0.17569   -27.41232 1.000 20.35641 ? 120 PRO B N   1 
ATOM   2073 C CA  . PRO B 1 120 ? -3.98903  0.02677   -28.86697 1.000 19.60868 ? 120 PRO B CA  1 
ATOM   2074 C C   . PRO B 1 120 ? -4.64130  1.22411   -29.54623 1.000 27.41151 ? 120 PRO B C   1 
ATOM   2075 O O   . PRO B 1 120 ? -5.10752  2.16342   -28.88759 1.000 24.20504 ? 120 PRO B O   1 
ATOM   2076 C CB  . PRO B 1 120 ? -4.80146  -1.25409  -29.06335 1.000 23.28644 ? 120 PRO B CB  1 
ATOM   2077 C CG  . PRO B 1 120 ? -5.79798  -1.20700  -27.94861 1.000 27.75574 ? 120 PRO B CG  1 
ATOM   2078 C CD  . PRO B 1 120 ? -5.12920  -0.47302  -26.78175 1.000 19.64163 ? 120 PRO B CD  1 
ATOM   2079 N N   . GLN B 1 121 ? -4.67793  1.19906   -30.87396 1.000 29.72898 ? 121 GLN B N   1 
ATOM   2080 C CA  . GLN B 1 121 ? -5.38525  2.23614   -31.60140 1.000 29.64151 ? 121 GLN B CA  1 
ATOM   2081 C C   . GLN B 1 121 ? -6.88914  2.12107   -31.34869 1.000 25.70638 ? 121 GLN B C   1 
ATOM   2082 O O   . GLN B 1 121 ? -7.40589  1.02083   -31.12655 1.000 26.83310 ? 121 GLN B O   1 
ATOM   2083 C CB  . GLN B 1 121 ? -5.08631  2.13288   -33.09280 1.000 24.48706 ? 121 GLN B CB  1 
ATOM   2084 C CG  . GLN B 1 121 ? -3.60479  2.14242   -33.39321 1.000 20.86897 ? 121 GLN B CG  1 
ATOM   2085 C CD  . GLN B 1 121 ? -2.91035  3.41640   -32.92336 1.000 25.09200 ? 121 GLN B CD  1 
ATOM   2086 O OE1 . GLN B 1 121 ? -1.71205  3.40054   -32.64404 1.000 31.42030 ? 121 GLN B OE1 1 
ATOM   2087 N NE2 . GLN B 1 121 ? -3.65401  4.52599   -32.84231 1.000 19.12539 ? 121 GLN B NE2 1 
ATOM   2088 N N   . PRO B 1 122 ? -7.60927  3.25013   -31.33838 1.000 28.05956 ? 122 PRO B N   1 
ATOM   2089 C CA  . PRO B 1 122 ? -9.07250  3.17335   -31.18941 1.000 27.11122 ? 122 PRO B CA  1 
ATOM   2090 C C   . PRO B 1 122 ? -9.71533  2.22676   -32.19117 1.000 33.44874 ? 122 PRO B C   1 
ATOM   2091 O O   . PRO B 1 122 ? -10.78893 1.67250   -31.92012 1.000 31.08937 ? 122 PRO B O   1 
ATOM   2092 C CB  . PRO B 1 122 ? -9.50947  4.63222   -31.37853 1.000 24.13635 ? 122 PRO B CB  1 
ATOM   2093 C CG  . PRO B 1 122 ? -8.32495  5.43236   -30.85830 1.000 15.87086 ? 122 PRO B CG  1 
ATOM   2094 C CD  . PRO B 1 122 ? -7.12252  4.64797   -31.32784 1.000 22.34473 ? 122 PRO B CD  1 
ATOM   2095 N N   . GLY B 1 123 ? -9.06511  1.99406   -33.33023 1.000 26.42407 ? 123 GLY B N   1 
ATOM   2096 C CA  . GLY B 1 123 ? -9.47118  0.93399   -34.22102 1.000 32.91916 ? 123 GLY B CA  1 
ATOM   2097 C C   . GLY B 1 123 ? -8.81362  -0.39769  -33.90614 1.000 42.96971 ? 123 GLY B C   1 
ATOM   2098 O O   . GLY B 1 123 ? -8.17220  -0.98464  -34.78351 1.000 43.97101 ? 123 GLY B O   1 
ATOM   2099 N N   . HIS B 1 124 ? -8.98183  -0.89412  -32.67365 1.000 34.19064 ? 124 HIS B N   1 
ATOM   2100 C CA  . HIS B 1 124 ? -8.42618  -2.17899  -32.27650 1.000 31.62550 ? 124 HIS B CA  1 
ATOM   2101 C C   . HIS B 1 124 ? -9.23416  -2.74593  -31.10857 1.000 37.85334 ? 124 HIS B C   1 
ATOM   2102 O O   . HIS B 1 124 ? -10.38289 -3.16378  -31.30311 1.000 47.64125 ? 124 HIS B O   1 
ATOM   2103 C CB  . HIS B 1 124 ? -6.94426  -2.02771  -31.93268 1.000 31.47292 ? 124 HIS B CB  1 
ATOM   2104 C CG  . HIS B 1 124 ? -6.01928  -2.53362  -32.99904 1.000 36.38197 ? 124 HIS B CG  1 
ATOM   2105 N ND1 . HIS B 1 124 ? -5.91311  -1.94448  -34.24049 1.000 48.64821 ? 124 HIS B ND1 1 
ATOM   2106 C CD2 . HIS B 1 124 ? -5.14909  -3.57375  -33.00424 1.000 39.18490 ? 124 HIS B CD2 1 
ATOM   2107 C CE1 . HIS B 1 124 ? -5.02955  -2.60698  -34.96824 1.000 45.50844 ? 124 HIS B CE1 1 
ATOM   2108 N NE2 . HIS B 1 124 ? -4.55099  -3.60086  -34.24093 1.000 45.32270 ? 124 HIS B NE2 1 
ATOM   2109 N N   . GLU B 1 125 ? -8.63437  -2.80201  -29.91291 1.000 23.25214 ? 125 GLU B N   1 
ATOM   2110 C CA  . GLU B 1 125 ? -9.34264  -2.89813  -28.63307 1.000 32.61312 ? 125 GLU B CA  1 
ATOM   2111 C C   . GLU B 1 125 ? -9.85215  -4.29941  -28.30979 1.000 35.11868 ? 125 GLU B C   1 
ATOM   2112 O O   . GLU B 1 125 ? -9.40643  -4.91845  -27.33434 1.000 31.75164 ? 125 GLU B O   1 
ATOM   2113 C CB  . GLU B 1 125 ? -10.52461 -1.92436  -28.58648 1.000 35.87696 ? 125 GLU B CB  1 
ATOM   2114 C CG  . GLU B 1 125 ? -10.18599 -0.47521  -28.84592 1.000 29.74964 ? 125 GLU B CG  1 
ATOM   2115 C CD  . GLU B 1 125 ? -11.41809 0.32937   -29.15681 1.000 36.42209 ? 125 GLU B CD  1 
ATOM   2116 O OE1 . GLU B 1 125 ? -12.31869 -0.21826  -29.83692 1.000 36.66344 ? 125 GLU B OE1 1 
ATOM   2117 O OE2 . GLU B 1 125 ? -11.48951 1.50124   -28.72208 1.000 39.79360 ? 125 GLU B OE2 1 
ATOM   2118 N N   . GLY B 1 126 ? -10.82520 -4.78056  -29.08608 1.000 36.80878 ? 126 GLY B N   1 
ATOM   2119 C CA  . GLY B 1 126 ? -11.32362 -6.13036  -28.87655 1.000 33.46334 ? 126 GLY B CA  1 
ATOM   2120 C C   . GLY B 1 126 ? -10.22270 -7.16517  -28.97972 1.000 35.67056 ? 126 GLY B C   1 
ATOM   2121 O O   . GLY B 1 126 ? -10.04943 -7.99642  -28.08575 1.000 44.06765 ? 126 GLY B O   1 
ATOM   2122 N N   . GLU B 1 127 ? -9.44338  -7.10924  -30.06234 1.000 33.60800 ? 127 GLU B N   1 
ATOM   2123 C CA  . GLU B 1 127 ? -8.30197  -8.00714  -30.20388 1.000 31.11439 ? 127 GLU B CA  1 
ATOM   2124 C C   . GLU B 1 127 ? -7.29243  -7.80684  -29.07590 1.000 33.92645 ? 127 GLU B C   1 
ATOM   2125 O O   . GLU B 1 127 ? -6.76360  -8.78032  -28.51885 1.000 37.30840 ? 127 GLU B O   1 
ATOM   2126 C CB  . GLU B 1 127 ? -7.63680  -7.79012  -31.56407 1.000 35.03822 ? 127 GLU B CB  1 
ATOM   2127 C CG  . GLU B 1 127 ? -8.43196  -8.30348  -32.76605 1.000 43.88980 ? 127 GLU B CG  1 
ATOM   2128 C CD  . GLU B 1 127 ? -9.54144  -7.36025  -33.21493 1.000 52.65648 ? 127 GLU B CD  1 
ATOM   2129 O OE1 . GLU B 1 127 ? -9.32058  -6.58206  -34.16677 1.000 57.84651 ? 127 GLU B OE1 1 
ATOM   2130 O OE2 . GLU B 1 127 ? -10.64046 -7.39996  -32.62335 1.000 58.37261 ? 127 GLU B OE2 1 
ATOM   2131 N N   . TRP B 1 128 ? -7.01902  -6.55002  -28.71702 1.000 25.92496 ? 128 TRP B N   1 
ATOM   2132 C CA  . TRP B 1 128 ? -6.00395  -6.26834  -27.70751 1.000 28.91612 ? 128 TRP B CA  1 
ATOM   2133 C C   . TRP B 1 128 ? -6.35082  -6.90076  -26.36221 1.000 28.95665 ? 128 TRP B C   1 
ATOM   2134 O O   . TRP B 1 128 ? -5.45667  -7.35329  -25.64302 1.000 25.95855 ? 128 TRP B O   1 
ATOM   2135 C CB  . TRP B 1 128 ? -5.82992  -4.75395  -27.58660 1.000 27.79740 ? 128 TRP B CB  1 
ATOM   2136 C CG  . TRP B 1 128 ? -5.07584  -4.25890  -26.39642 1.000 27.36283 ? 128 TRP B CG  1 
ATOM   2137 C CD1 . TRP B 1 128 ? -3.73194  -4.12945  -26.27824 1.000 29.23167 ? 128 TRP B CD1 1 
ATOM   2138 C CD2 . TRP B 1 128 ? -5.63226  -3.77502  -25.16979 1.000 26.67566 ? 128 TRP B CD2 1 
ATOM   2139 N NE1 . TRP B 1 128 ? -3.41159  -3.60881  -25.05250 1.000 21.26427 ? 128 TRP B NE1 1 
ATOM   2140 C CE2 . TRP B 1 128 ? -4.56385  -3.39056  -24.35034 1.000 22.26570 ? 128 TRP B CE2 1 
ATOM   2141 C CE3 . TRP B 1 128 ? -6.93197  -3.64626  -24.68014 1.000 30.44805 ? 128 TRP B CE3 1 
ATOM   2142 C CZ2 . TRP B 1 128 ? -4.75313  -2.88020  -23.07143 1.000 25.07065 ? 128 TRP B CZ2 1 
ATOM   2143 C CZ3 . TRP B 1 128 ? -7.11325  -3.12503  -23.42196 1.000 25.29897 ? 128 TRP B CZ3 1 
ATOM   2144 C CH2 . TRP B 1 128 ? -6.03479  -2.75825  -22.63103 1.000 25.73600 ? 128 TRP B CH2 1 
ATOM   2145 N N   . PHE B 1 129 ? -7.63762  -6.96280  -26.01726 1.000 29.99455 ? 129 PHE B N   1 
ATOM   2146 C CA  . PHE B 1 129 ? -8.02967  -7.50162  -24.71911 1.000 30.71734 ? 129 PHE B CA  1 
ATOM   2147 C C   . PHE B 1 129 ? -7.76707  -8.99967  -24.64942 1.000 33.31455 ? 129 PHE B C   1 
ATOM   2148 O O   . PHE B 1 129 ? -7.18832  -9.48686  -23.66818 1.000 29.71011 ? 129 PHE B O   1 
ATOM   2149 C CB  . PHE B 1 129 ? -9.50089  -7.17101  -24.44723 1.000 27.89874 ? 129 PHE B CB  1 
ATOM   2150 C CG  . PHE B 1 129 ? -10.07081 -7.82238  -23.21585 1.000 30.74156 ? 129 PHE B CG  1 
ATOM   2151 C CD1 . PHE B 1 129 ? -10.82191 -8.98660  -23.31283 1.000 35.85934 ? 129 PHE B CD1 1 
ATOM   2152 C CD2 . PHE B 1 129 ? -9.89121  -7.25700  -21.96488 1.000 35.84894 ? 129 PHE B CD2 1 
ATOM   2153 C CE1 . PHE B 1 129 ? -11.36939 -9.58224  -22.18354 1.000 33.12056 ? 129 PHE B CE1 1 
ATOM   2154 C CE2 . PHE B 1 129 ? -10.43355 -7.85120  -20.82182 1.000 31.23077 ? 129 PHE B CE2 1 
ATOM   2155 C CZ  . PHE B 1 129 ? -11.17123 -9.01533  -20.93070 1.000 26.38079 ? 129 PHE B CZ  1 
ATOM   2156 N N   . ASP B 1 130 ? -8.14159  -9.73420  -25.70270 1.000 32.63281 ? 130 ASP B N   1 
ATOM   2157 C CA  . ASP B 1 130 ? -8.00263  -11.18859 -25.69586 1.000 35.98585 ? 130 ASP B CA  1 
ATOM   2158 C C   . ASP B 1 130 ? -6.54934  -11.62102 -25.53914 1.000 36.74762 ? 130 ASP B C   1 
ATOM   2159 O O   . ASP B 1 130 ? -6.25155  -12.54091 -24.76794 1.000 34.94751 ? 130 ASP B O   1 
ATOM   2160 C CB  . ASP B 1 130 ? -8.58566  -11.78921 -26.97870 1.000 43.57119 ? 130 ASP B CB  1 
ATOM   2161 C CG  . ASP B 1 130 ? -10.09758 -11.67202 -27.04701 1.000 45.97732 ? 130 ASP B CG  1 
ATOM   2162 O OD1 . ASP B 1 130 ? -10.67368 -12.02620 -28.09797 1.000 40.49934 ? 130 ASP B OD1 1 
ATOM   2163 O OD2 . ASP B 1 130 ? -10.70105 -11.21121 -26.04990 1.000 48.34735 ? 130 ASP B OD2 1 
ATOM   2164 N N   . ASN B 1 131 ? -5.62705  -10.97541 -26.25300 1.000 31.91561 ? 131 ASN B N   1 
ATOM   2165 C CA  . ASN B 1 131 ? -4.25968  -11.47367 -26.24915 1.000 30.84588 ? 131 ASN B CA  1 
ATOM   2166 C C   . ASN B 1 131 ? -3.44447  -11.01514 -25.03873 1.000 32.19080 ? 131 ASN B C   1 
ATOM   2167 O O   . ASN B 1 131 ? -2.25982  -11.35193 -24.95096 1.000 31.77412 ? 131 ASN B O   1 
ATOM   2168 C CB  . ASN B 1 131 ? -3.56857  -11.09326 -27.55771 1.000 38.69419 ? 131 ASN B CB  1 
ATOM   2169 C CG  . ASN B 1 131 ? -4.00809  -11.97679 -28.72148 1.000 46.58435 ? 131 ASN B CG  1 
ATOM   2170 O OD1 . ASN B 1 131 ? -3.45298  -13.06634 -28.94599 1.000 44.92414 ? 131 ASN B OD1 1 
ATOM   2171 N ND2 . ASN B 1 131 ? -5.02202  -11.51932 -29.45917 1.000 38.95015 ? 131 ASN B ND2 1 
ATOM   2172 N N   . LEU B 1 132 ? -4.04614  -10.28256 -24.10196 1.000 34.89641 ? 132 LEU B N   1 
ATOM   2173 C CA  . LEU B 1 132 ? -3.44748  -10.07583 -22.79231 1.000 27.39464 ? 132 LEU B CA  1 
ATOM   2174 C C   . LEU B 1 132 ? -3.54485  -11.35378 -21.96469 1.000 31.87733 ? 132 LEU B C   1 
ATOM   2175 O O   . LEU B 1 132 ? -4.33986  -12.25281 -22.25297 1.000 28.19595 ? 132 LEU B O   1 
ATOM   2176 C CB  . LEU B 1 132 ? -4.14339  -8.93987  -22.04992 1.000 26.35549 ? 132 LEU B CB  1 
ATOM   2177 C CG  . LEU B 1 132 ? -4.03721  -7.50503  -22.56205 1.000 29.21279 ? 132 LEU B CG  1 
ATOM   2178 C CD1 . LEU B 1 132 ? -4.49247  -6.56028  -21.47461 1.000 28.58125 ? 132 LEU B CD1 1 
ATOM   2179 C CD2 . LEU B 1 132 ? -2.62072  -7.15231  -22.99575 1.000 31.86323 ? 132 LEU B CD2 1 
ATOM   2180 N N   . SER B 1 133 ? -2.74108  -11.41570 -20.90451 1.000 34.21874 ? 133 SER B N   1 
ATOM   2181 C CA  . SER B 1 133 ? -2.71207  -12.60716 -20.06681 1.000 37.15530 ? 133 SER B CA  1 
ATOM   2182 C C   . SER B 1 133 ? -4.07244  -12.85709 -19.39830 1.000 33.17851 ? 133 SER B C   1 
ATOM   2183 O O   . SER B 1 133 ? -4.99050  -12.03607 -19.43971 1.000 31.93905 ? 133 SER B O   1 
ATOM   2184 C CB  . SER B 1 133 ? -1.60421  -12.49993 -19.01503 1.000 33.09952 ? 133 SER B CB  1 
ATOM   2185 O OG  . SER B 1 133 ? -2.05781  -11.87782 -17.83793 1.000 33.21780 ? 133 SER B OG  1 
ATOM   2186 N N   . SER B 1 134 ? -4.19084  -14.03332 -18.78557 1.000 27.99434 ? 134 SER B N   1 
ATOM   2187 C CA  . SER B 1 134 ? -5.43689  -14.40428 -18.13230 1.000 29.64258 ? 134 SER B CA  1 
ATOM   2188 C C   . SER B 1 134 ? -5.65862  -13.58159 -16.86848 1.000 32.09059 ? 134 SER B C   1 
ATOM   2189 O O   . SER B 1 134 ? -6.74547  -13.03586 -16.64886 1.000 34.50704 ? 134 SER B O   1 
ATOM   2190 C CB  . SER B 1 134 ? -5.42594  -15.90146 -17.80914 1.000 33.46589 ? 134 SER B CB  1 
ATOM   2191 O OG  . SER B 1 134 ? -5.35842  -16.68735 -18.98426 1.000 31.10035 ? 134 SER B OG  1 
ATOM   2192 N N   . ASP B 1 135 ? -4.64414  -13.50529 -16.00713 1.000 39.77847 ? 135 ASP B N   1 
ATOM   2193 C CA  . ASP B 1 135 ? -4.79440  -12.74375 -14.77441 1.000 34.94088 ? 135 ASP B CA  1 
ATOM   2194 C C   . ASP B 1 135 ? -5.03001  -11.26901 -15.06842 1.000 32.48874 ? 135 ASP B C   1 
ATOM   2195 O O   . ASP B 1 135 ? -5.78750  -10.60828 -14.35026 1.000 31.87526 ? 135 ASP B O   1 
ATOM   2196 C CB  . ASP B 1 135 ? -3.56532  -12.94243 -13.88345 1.000 28.67557 ? 135 ASP B CB  1 
ATOM   2197 C CG  . ASP B 1 135 ? -3.51597  -14.33279 -13.24225 1.000 39.15965 ? 135 ASP B CG  1 
ATOM   2198 O OD1 . ASP B 1 135 ? -4.58482  -14.92799 -12.96992 1.000 37.05220 ? 135 ASP B OD1 1 
ATOM   2199 O OD2 . ASP B 1 135 ? -2.39613  -14.83201 -12.99655 1.000 45.95563 ? 135 ASP B OD2 1 
ATOM   2200 N N   . GLU B 1 136 ? -4.42543  -10.74661 -16.13727 1.000 27.90174 ? 136 GLU B N   1 
ATOM   2201 C CA  . GLU B 1 136 ? -4.63427  -9.34424  -16.47392 1.000 30.45143 ? 136 GLU B CA  1 
ATOM   2202 C C   . GLU B 1 136 ? -6.07457  -9.09031  -16.90310 1.000 29.68276 ? 136 GLU B C   1 
ATOM   2203 O O   . GLU B 1 136 ? -6.69046  -8.11072  -16.46263 1.000 32.10348 ? 136 GLU B O   1 
ATOM   2204 C CB  . GLU B 1 136 ? -3.63809  -8.91936  -17.55192 1.000 24.52062 ? 136 GLU B CB  1 
ATOM   2205 C CG  . GLU B 1 136 ? -2.20500  -8.97234  -17.06921 1.000 20.60334 ? 136 GLU B CG  1 
ATOM   2206 C CD  . GLU B 1 136 ? -1.18425  -8.60632  -18.14076 1.000 27.77679 ? 136 GLU B CD  1 
ATOM   2207 O OE1 . GLU B 1 136 ? -1.09716  -9.29962  -19.17341 1.000 23.32198 ? 136 GLU B OE1 1 
ATOM   2208 O OE2 . GLU B 1 136 ? -0.46145  -7.60999  -17.94870 1.000 37.91815 ? 136 GLU B OE2 1 
ATOM   2209 N N   . ARG B 1 137 ? -6.63756  -9.98335  -17.73174 1.000 26.83982 ? 137 ARG B N   1 
ATOM   2210 C CA  . ARG B 1 137 ? -8.03786  -9.89534  -18.14061 1.000 28.21516 ? 137 ARG B CA  1 
ATOM   2211 C C   . ARG B 1 137 ? -9.00720  -10.14518 -16.99669 1.000 34.36279 ? 137 ARG B C   1 
ATOM   2212 O O   . ARG B 1 137 ? -10.15786 -9.70273  -17.07721 1.000 34.95747 ? 137 ARG B O   1 
ATOM   2213 C CB  . ARG B 1 137 ? -8.35127  -10.89849 -19.25081 1.000 31.39184 ? 137 ARG B CB  1 
ATOM   2214 C CG  . ARG B 1 137 ? -7.73245  -10.58257 -20.59593 1.000 29.92270 ? 137 ARG B CG  1 
ATOM   2215 C CD  . ARG B 1 137 ? -7.86413  -11.76159 -21.53100 1.000 34.92774 ? 137 ARG B CD  1 
ATOM   2216 N NE  . ARG B 1 137 ? -9.20915  -11.90965 -22.07525 1.000 35.03130 ? 137 ARG B NE  1 
ATOM   2217 C CZ  . ARG B 1 137 ? -9.63219  -13.00520 -22.69286 1.000 44.78974 ? 137 ARG B CZ  1 
ATOM   2218 N NH1 . ARG B 1 137 ? -8.86249  -14.07635 -22.79397 1.000 46.97927 ? 137 ARG B NH1 1 
ATOM   2219 N NH2 . ARG B 1 137 ? -10.85465 -13.02724 -23.22315 1.000 39.05479 ? 137 ARG B NH2 1 
ATOM   2220 N N   . ALA B 1 138 ? -8.58740  -10.87390 -15.95613 1.000 34.33727 ? 138 ALA B N   1 
ATOM   2221 C CA  . ALA B 1 138 ? -9.47044  -11.13098 -14.82157 1.000 33.93361 ? 138 ALA B CA  1 
ATOM   2222 C C   . ALA B 1 138 ? -9.60608  -9.89703  -13.94359 1.000 28.75903 ? 138 ALA B C   1 
ATOM   2223 O O   . ALA B 1 138 ? -10.71560 -9.51895  -13.55798 1.000 28.41550 ? 138 ALA B O   1 
ATOM   2224 C CB  . ALA B 1 138 ? -8.95570  -12.31187 -14.00100 1.000 36.55350 ? 138 ALA B CB  1 
ATOM   2225 N N   . PHE B 1 139 ? -8.47619  -9.25933  -13.63036 1.000 34.72924 ? 139 PHE B N   1 
ATOM   2226 C CA  . PHE B 1 139 ? -8.48890  -8.01329  -12.87271 1.000 31.28949 ? 139 PHE B CA  1 
ATOM   2227 C C   . PHE B 1 139 ? -9.27702  -6.92953  -13.59729 1.000 33.80525 ? 139 PHE B C   1 
ATOM   2228 O O   . PHE B 1 139 ? -9.89260  -6.06226  -12.95874 1.000 31.00740 ? 139 PHE B O   1 
ATOM   2229 C CB  . PHE B 1 139 ? -7.05165  -7.55779  -12.61811 1.000 24.60842 ? 139 PHE B CB  1 
ATOM   2230 C CG  . PHE B 1 139 ? -6.94693  -6.26471  -11.85407 1.000 31.29642 ? 139 PHE B CG  1 
ATOM   2231 C CD1 . PHE B 1 139 ? -7.31322  -6.20156  -10.52257 1.000 29.27316 ? 139 PHE B CD1 1 
ATOM   2232 C CD2 . PHE B 1 139 ? -6.46827  -5.11697  -12.46701 1.000 27.07881 ? 139 PHE B CD2 1 
ATOM   2233 C CE1 . PHE B 1 139 ? -7.21477  -5.01948  -9.81813  1.000 31.31322 ? 139 PHE B CE1 1 
ATOM   2234 C CE2 . PHE B 1 139 ? -6.36245  -3.93202  -11.77408 1.000 31.39522 ? 139 PHE B CE2 1 
ATOM   2235 C CZ  . PHE B 1 139 ? -6.73914  -3.87971  -10.44024 1.000 33.16216 ? 139 PHE B CZ  1 
ATOM   2236 N N   . MET B 1 140 ? -9.27688  -6.96616  -14.92519 1.000 28.26167 ? 140 MET B N   1 
ATOM   2237 C CA  . MET B 1 140 ? -10.02887 -5.97333  -15.66785 1.000 31.50487 ? 140 MET B CA  1 
ATOM   2238 C C   . MET B 1 140 ? -11.52355 -6.21283  -15.53525 1.000 33.31061 ? 140 MET B C   1 
ATOM   2239 O O   . MET B 1 140 ? -12.29227 -5.26610  -15.33245 1.000 31.73878 ? 140 MET B O   1 
ATOM   2240 C CB  . MET B 1 140 ? -9.59347  -5.98388  -17.12902 1.000 30.24686 ? 140 MET B CB  1 
ATOM   2241 C CG  . MET B 1 140 ? -8.51657  -4.98081  -17.43766 1.000 27.20552 ? 140 MET B CG  1 
ATOM   2242 S SD  . MET B 1 140 ? -7.76250  -5.22677  -19.04183 1.000 28.91647 ? 140 MET B SD  1 
ATOM   2243 C CE  . MET B 1 140 ? -6.12038  -5.69376  -18.53263 1.000 30.94016 ? 140 MET B CE  1 
ATOM   2244 N N   . GLU B 1 141 ? -11.95040 -7.47574  -15.61915 1.000 41.16779 ? 141 GLU B N   1 
ATOM   2245 C CA  . GLU B 1 141 ? -13.36915 -7.80899  -15.50274 1.000 42.26427 ? 141 GLU B CA  1 
ATOM   2246 C C   . GLU B 1 141 ? -13.95602 -7.42741  -14.13850 1.000 39.38641 ? 141 GLU B C   1 
ATOM   2247 O O   . GLU B 1 141 ? -15.18024 -7.32811  -14.01206 1.000 36.76677 ? 141 GLU B O   1 
ATOM   2248 C CB  . GLU B 1 141 ? -13.56128 -9.30389  -15.78493 1.000 41.14193 ? 141 GLU B CB  1 
ATOM   2249 C CG  . GLU B 1 141 ? -15.01272 -9.75617  -16.00647 1.000 60.65794 ? 141 GLU B CG  1 
ATOM   2250 C CD  . GLU B 1 141 ? -15.70578 -10.24150 -14.72774 1.000 66.49671 ? 141 GLU B CD  1 
ATOM   2251 O OE1 . GLU B 1 141 ? -16.88387 -10.66957 -14.81092 1.000 67.60197 ? 141 GLU B OE1 1 
ATOM   2252 O OE2 . GLU B 1 141 ? -15.07082 -10.20470 -13.64514 1.000 63.97293 ? 141 GLU B OE2 1 
ATOM   2253 N N   . THR B 1 142 ? -13.11356 -7.19402  -13.12555 1.000 27.34062 ? 142 THR B N   1 
ATOM   2254 C CA  . THR B 1 142 ? -13.61073 -6.78684  -11.81366 1.000 33.69224 ? 142 THR B CA  1 
ATOM   2255 C C   . THR B 1 142 ? -14.21200 -5.38266  -11.85043 1.000 42.19245 ? 142 THR B C   1 
ATOM   2256 O O   . THR B 1 142 ? -15.22265 -5.11637  -11.18796 1.000 44.46833 ? 142 THR B O   1 
ATOM   2257 C CB  . THR B 1 142 ? -12.47925 -6.86861  -10.78645 1.000 37.09192 ? 142 THR B CB  1 
ATOM   2258 O OG1 . THR B 1 142 ? -12.26728 -8.23674  -10.42020 1.000 35.70707 ? 142 THR B OG1 1 
ATOM   2259 C CG2 . THR B 1 142 ? -12.79570 -6.05816  -9.53490  1.000 45.22075 ? 142 THR B CG2 1 
ATOM   2260 N N   . ASN B 1 143 ? -13.63114 -4.48114  -12.63871 1.000 37.25211 ? 143 ASN B N   1 
ATOM   2261 C CA  . ASN B 1 143 ? -14.06275 -3.08622  -12.66158 1.000 36.35817 ? 143 ASN B CA  1 
ATOM   2262 C C   . ASN B 1 143 ? -15.04935 -2.82990  -13.80484 1.000 35.10140 ? 143 ASN B C   1 
ATOM   2263 O O   . ASN B 1 143 ? -14.74474 -2.17913  -14.80254 1.000 34.81231 ? 143 ASN B O   1 
ATOM   2264 C CB  . ASN B 1 143 ? -12.84654 -2.17493  -12.75289 1.000 34.32081 ? 143 ASN B CB  1 
ATOM   2265 C CG  . ASN B 1 143 ? -11.94513 -2.30962  -11.54826 1.000 34.20685 ? 143 ASN B CG  1 
ATOM   2266 O OD1 . ASN B 1 143 ? -12.42332 -2.36911  -10.41823 1.000 33.38636 ? 143 ASN B OD1 1 
ATOM   2267 N ND2 . ASN B 1 143 ? -10.63970 -2.38942  -11.78173 1.000 30.62076 ? 143 ASN B ND2 1 
ATOM   2268 N N   . VAL B 1 144 ? -16.27214 -3.32866  -13.62291 1.000 37.17605 ? 144 VAL B N   1 
ATOM   2269 C CA  . VAL B 1 144 ? -17.38339 -3.04250  -14.52582 1.000 38.27281 ? 144 VAL B CA  1 
ATOM   2270 C C   . VAL B 1 144 ? -18.56687 -2.51580  -13.71742 1.000 40.60140 ? 144 VAL B C   1 
ATOM   2271 O O   . VAL B 1 144 ? -18.84798 -3.00616  -12.61713 1.000 42.31019 ? 144 VAL B O   1 
ATOM   2272 C CB  . VAL B 1 144 ? -17.79699 -4.28771  -15.34273 1.000 42.18012 ? 144 VAL B CB  1 
ATOM   2273 C CG1 . VAL B 1 144 ? -18.90048 -3.93528  -16.33591 1.000 38.47224 ? 144 VAL B CG1 1 
ATOM   2274 C CG2 . VAL B 1 144 ? -16.58971 -4.89472  -16.05870 1.000 42.66435 ? 144 VAL B CG2 1 
ATOM   2275 N N   . ASP B 1 145 ? -19.25489 -1.51402  -14.26833 1.000 40.39998 ? 145 ASP B N   1 
ATOM   2276 C CA  . ASP B 1 145 ? -20.49261 -0.96949  -13.70262 1.000 36.52008 ? 145 ASP B CA  1 
ATOM   2277 C C   . ASP B 1 145 ? -21.14476 -0.00089  -14.69905 1.000 49.12515 ? 145 ASP B C   1 
ATOM   2278 O O   . ASP B 1 145 ? -22.37493 0.10220   -14.80098 1.000 45.20740 ? 145 ASP B O   1 
ATOM   2279 C CB  . ASP B 1 145 ? -20.23067 -0.25419  -12.37989 1.000 32.89288 ? 145 ASP B CB  1 
ATOM   2280 C CG  . ASP B 1 145 ? -21.44844 0.51468   -11.88480 1.000 44.70399 ? 145 ASP B CG  1 
ATOM   2281 O OD1 . ASP B 1 145 ? -22.38476 -0.12350  -11.36443 1.000 46.43484 ? 145 ASP B OD1 1 
ATOM   2282 O OD2 . ASP B 1 145 ? -21.47777 1.75514   -12.02711 1.000 45.78709 ? 145 ASP B OD2 1 
ATOM   2283 N N   . PRO C 1 1   ? -10.17947 29.41567  -21.83152 1.000 25.57023 ? 1   PRO C N   1 
ATOM   2284 C CA  . PRO C 1 1   ? -9.09592  28.72128  -21.15077 1.000 22.94147 ? 1   PRO C CA  1 
ATOM   2285 C C   . PRO C 1 1   ? -9.44124  28.24327  -19.77608 1.000 20.21383 ? 1   PRO C C   1 
ATOM   2286 O O   . PRO C 1 1   ? -10.25967 28.86017  -19.09919 1.000 25.93062 ? 1   PRO C O   1 
ATOM   2287 C CB  . PRO C 1 1   ? -8.00190  29.77089  -21.02825 1.000 20.85831 ? 1   PRO C CB  1 
ATOM   2288 C CG  . PRO C 1 1   ? -8.75434  31.03864  -20.99384 1.000 31.89257 ? 1   PRO C CG  1 
ATOM   2289 C CD  . PRO C 1 1   ? -9.85897  30.83316  -21.99967 1.000 30.31585 ? 1   PRO C CD  1 
ATOM   2290 N N   . VAL C 1 2   ? -8.78300  27.16810  -19.36563 1.000 16.07165 ? 2   VAL C N   1 
ATOM   2291 C CA  . VAL C 1 2   ? -8.67159  26.80281  -17.96245 1.000 21.29327 ? 2   VAL C CA  1 
ATOM   2292 C C   . VAL C 1 2   ? -7.19984  26.89861  -17.59248 1.000 20.80491 ? 2   VAL C C   1 
ATOM   2293 O O   . VAL C 1 2   ? -6.33507  26.38447  -18.31134 1.000 19.20316 ? 2   VAL C O   1 
ATOM   2294 C CB  . VAL C 1 2   ? -9.22918  25.39381  -17.67618 1.000 17.19031 ? 2   VAL C CB  1 
ATOM   2295 C CG1 . VAL C 1 2   ? -9.08004  25.04925  -16.20945 1.000 17.67414 ? 2   VAL C CG1 1 
ATOM   2296 C CG2 . VAL C 1 2   ? -10.67470 25.30522  -18.05884 1.000 14.86880 ? 2   VAL C CG2 1 
ATOM   2297 N N   . TYR C 1 3   ? -6.91294  27.57741  -16.49008 1.000 21.37468 ? 3   TYR C N   1 
ATOM   2298 C CA  . TYR C 1 3   ? -5.58708  27.55634  -15.89047 1.000 17.48885 ? 3   TYR C CA  1 
ATOM   2299 C C   . TYR C 1 3   ? -5.63915  26.72705  -14.61151 1.000 21.30397 ? 3   TYR C C   1 
ATOM   2300 O O   . TYR C 1 3   ? -6.37099  27.07382  -13.67887 1.000 19.01508 ? 3   TYR C O   1 
ATOM   2301 C CB  . TYR C 1 3   ? -5.09617  28.96761  -15.60065 1.000 18.09398 ? 3   TYR C CB  1 
ATOM   2302 C CG  . TYR C 1 3   ? -4.74733  29.75874  -16.82343 1.000 19.50933 ? 3   TYR C CG  1 
ATOM   2303 C CD1 . TYR C 1 3   ? -3.49558  29.65167  -17.40200 1.000 16.75589 ? 3   TYR C CD1 1 
ATOM   2304 C CD2 . TYR C 1 3   ? -5.65548  30.63273  -17.39001 1.000 20.31443 ? 3   TYR C CD2 1 
ATOM   2305 C CE1 . TYR C 1 3   ? -3.16701  30.38073  -18.51216 1.000 16.39909 ? 3   TYR C CE1 1 
ATOM   2306 C CE2 . TYR C 1 3   ? -5.32236  31.37760  -18.50682 1.000 20.10735 ? 3   TYR C CE2 1 
ATOM   2307 C CZ  . TYR C 1 3   ? -4.08211  31.24470  -19.06029 1.000 15.83821 ? 3   TYR C CZ  1 
ATOM   2308 O OH  . TYR C 1 3   ? -3.73500  31.96707  -20.18036 1.000 16.62200 ? 3   TYR C OH  1 
ATOM   2309 N N   . MET C 1 4   ? -4.88128  25.62519  -14.59126 1.000 22.04524 ? 4   MET C N   1 
ATOM   2310 C CA  . MET C 1 4   ? -4.68424  24.80285  -13.40210 1.000 22.35930 ? 4   MET C CA  1 
ATOM   2311 C C   . MET C 1 4   ? -3.48271  25.35166  -12.63723 1.000 21.03670 ? 4   MET C C   1 
ATOM   2312 O O   . MET C 1 4   ? -2.36831  25.38010  -13.16726 1.000 21.91478 ? 4   MET C O   1 
ATOM   2313 C CB  . MET C 1 4   ? -4.44174  23.33221  -13.76166 1.000 17.45388 ? 4   MET C CB  1 
ATOM   2314 C CG  . MET C 1 4   ? -5.47726  22.66267  -14.62394 1.000 15.83882 ? 4   MET C CG  1 
ATOM   2315 S SD  . MET C 1 4   ? -7.20670  22.93551  -14.14913 1.000 20.92998 ? 4   MET C SD  1 
ATOM   2316 C CE  . MET C 1 4   ? -7.18653  22.44378  -12.40379 1.000 18.38279 ? 4   MET C CE  1 
ATOM   2317 N N   . VAL C 1 5   ? -3.69259  25.77824  -11.39994 1.000 17.87603 ? 5   VAL C N   1 
ATOM   2318 C CA  . VAL C 1 5   ? -2.65367  26.49567  -10.66641 1.000 21.05196 ? 5   VAL C CA  1 
ATOM   2319 C C   . VAL C 1 5   ? -2.28161  25.64316  -9.46194  1.000 20.87099 ? 5   VAL C C   1 
ATOM   2320 O O   . VAL C 1 5   ? -3.00310  25.61389  -8.46036  1.000 21.25373 ? 5   VAL C O   1 
ATOM   2321 C CB  . VAL C 1 5   ? -3.09443  27.90789  -10.26014 1.000 20.59047 ? 5   VAL C CB  1 
ATOM   2322 C CG1 . VAL C 1 5   ? -1.92998  28.67077  -9.64712  1.000 23.46635 ? 5   VAL C CG1 1 
ATOM   2323 C CG2 . VAL C 1 5   ? -3.61340  28.67188  -11.47922 1.000 14.35504 ? 5   VAL C CG2 1 
ATOM   2324 N N   . TYR C 1 6   ? -1.15613  24.94352  -9.55620  1.000 19.32965 ? 6   TYR C N   1 
ATOM   2325 C CA  . TYR C 1 6   ? -0.72720  24.01117  -8.51607  1.000 20.25786 ? 6   TYR C CA  1 
ATOM   2326 C C   . TYR C 1 6   ? 0.11045   24.76915  -7.48840  1.000 24.41150 ? 6   TYR C C   1 
ATOM   2327 O O   . TYR C 1 6   ? 1.21342   25.23585  -7.79648  1.000 29.31342 ? 6   TYR C O   1 
ATOM   2328 C CB  . TYR C 1 6   ? 0.01933   22.83410  -9.14004  1.000 12.71524 ? 6   TYR C CB  1 
ATOM   2329 C CG  . TYR C 1 6   ? -0.91602  22.05812  -10.05699 1.000 22.20387 ? 6   TYR C CG  1 
ATOM   2330 C CD1 . TYR C 1 6   ? -1.91842  21.23736  -9.52800  1.000 14.00845 ? 6   TYR C CD1 1 
ATOM   2331 C CD2 . TYR C 1 6   ? -0.85398  22.21639  -11.45084 1.000 19.47235 ? 6   TYR C CD2 1 
ATOM   2332 C CE1 . TYR C 1 6   ? -2.80653  20.56621  -10.35927 1.000 18.01543 ? 6   TYR C CE1 1 
ATOM   2333 C CE2 . TYR C 1 6   ? -1.73929  21.55442  -12.28942 1.000 15.09685 ? 6   TYR C CE2 1 
ATOM   2334 C CZ  . TYR C 1 6   ? -2.71041  20.73501  -11.73723 1.000 19.26509 ? 6   TYR C CZ  1 
ATOM   2335 O OH  . TYR C 1 6   ? -3.58096  20.08246  -12.55856 1.000 20.66650 ? 6   TYR C OH  1 
ATOM   2336 N N   . VAL C 1 7   ? -0.43444  24.91291  -6.27797  1.000 21.06036 ? 7   VAL C N   1 
ATOM   2337 C CA  . VAL C 1 7   ? 0.17152   25.68931  -5.20162  1.000 26.25462 ? 7   VAL C CA  1 
ATOM   2338 C C   . VAL C 1 7   ? 0.18109   24.85711  -3.92606  1.000 21.64445 ? 7   VAL C C   1 
ATOM   2339 O O   . VAL C 1 7   ? -0.74288  24.07607  -3.66442  1.000 23.32751 ? 7   VAL C O   1 
ATOM   2340 C CB  . VAL C 1 7   ? -0.56002  27.03325  -4.95969  1.000 25.71495 ? 7   VAL C CB  1 
ATOM   2341 C CG1 . VAL C 1 7   ? 0.06252   28.12787  -5.79825  1.000 22.24843 ? 7   VAL C CG1 1 
ATOM   2342 C CG2 . VAL C 1 7   ? -2.05404  26.90990  -5.26261  1.000 20.61366 ? 7   VAL C CG2 1 
ATOM   2343 N N   . SER C 1 8   ? 1.23185   25.02887  -3.13579  1.000 22.41228 ? 8   SER C N   1 
ATOM   2344 C CA  . SER C 1 8   ? 1.31731   24.36566  -1.83661  1.000 29.85235 ? 8   SER C CA  1 
ATOM   2345 C C   . SER C 1 8   ? 0.25968   24.89762  -0.88162  1.000 28.17204 ? 8   SER C C   1 
ATOM   2346 O O   . SER C 1 8   ? -0.00664  26.10471  -0.83117  1.000 26.48327 ? 8   SER C O   1 
ATOM   2347 C CB  . SER C 1 8   ? 2.69788   24.58568  -1.22456  1.000 26.19986 ? 8   SER C CB  1 
ATOM   2348 O OG  . SER C 1 8   ? 3.41579   23.37323  -1.06398  1.000 30.58064 ? 8   SER C OG  1 
ATOM   2349 N N   . GLN C 1 9   ? -0.34637  23.99380  -0.11517  1.000 27.63395 ? 9   GLN C N   1 
ATOM   2350 C CA  . GLN C 1 9   ? -1.28628  24.42941  0.90855   1.000 34.54775 ? 9   GLN C CA  1 
ATOM   2351 C C   . GLN C 1 9   ? -0.59458  25.37529  1.90027   1.000 32.03013 ? 9   GLN C C   1 
ATOM   2352 O O   . GLN C 1 9   ? 0.51383   25.09737  2.36580   1.000 26.97317 ? 9   GLN C O   1 
ATOM   2353 C CB  . GLN C 1 9   ? -1.88274  23.21656  1.62429   1.000 28.64707 ? 9   GLN C CB  1 
ATOM   2354 C CG  . GLN C 1 9   ? -3.11745  23.54848  2.48481   1.000 31.05520 ? 9   GLN C CG  1 
ATOM   2355 C CD  . GLN C 1 9   ? -4.31863  24.01309  1.66176   1.000 38.59701 ? 9   GLN C CD  1 
ATOM   2356 O OE1 . GLN C 1 9   ? -4.87145  23.25062  0.86171   1.000 33.55484 ? 9   GLN C OE1 1 
ATOM   2357 N NE2 . GLN C 1 9   ? -4.73060  25.27307  1.86037   1.000 40.09126 ? 9   GLN C NE2 1 
ATOM   2358 N N   . ASP C 1 10  ? -1.25293  26.51113  2.17650   1.000 30.49240 ? 10  ASP C N   1 
ATOM   2359 C CA  . ASP C 1 10  ? -0.84153  27.59957  3.07455   1.000 38.09046 ? 10  ASP C CA  1 
ATOM   2360 C C   . ASP C 1 10  ? -0.09401  28.73216  2.36236   1.000 41.50964 ? 10  ASP C C   1 
ATOM   2361 O O   . ASP C 1 10  ? 0.34444   29.68492  3.01619   1.000 49.25959 ? 10  ASP C O   1 
ATOM   2362 C CB  . ASP C 1 10  ? 0.02572   27.10344  4.24177   1.000 38.12627 ? 10  ASP C CB  1 
ATOM   2363 C CG  . ASP C 1 10  ? -0.73856  26.21602  5.21393   1.000 41.06223 ? 10  ASP C CG  1 
ATOM   2364 O OD1 . ASP C 1 10  ? -1.79015  26.65888  5.73163   1.000 40.50596 ? 10  ASP C OD1 1 
ATOM   2365 O OD2 . ASP C 1 10  ? -0.27493  25.07557  5.46501   1.000 34.39284 ? 10  ASP C OD2 1 
ATOM   2366 N N   . ARG C 1 11  ? 0.05765   28.66559  1.03915   1.000 35.98985 ? 11  ARG C N   1 
ATOM   2367 C CA  . ARG C 1 11  ? 0.81913   29.69942  0.35010   1.000 33.19203 ? 11  ARG C CA  1 
ATOM   2368 C C   . ARG C 1 11  ? -0.01273  30.92887  0.00397   1.000 36.58167 ? 11  ARG C C   1 
ATOM   2369 O O   . ARG C 1 11  ? 0.50862   32.04594  0.03589   1.000 39.33470 ? 11  ARG C O   1 
ATOM   2370 C CB  . ARG C 1 11  ? 1.44352   29.14052  -0.92666  1.000 35.64782 ? 11  ARG C CB  1 
ATOM   2371 C CG  . ARG C 1 11  ? 2.52861   30.03028  -1.51235  1.000 43.62118 ? 11  ARG C CG  1 
ATOM   2372 C CD  . ARG C 1 11  ? 3.71017   30.13502  -0.55261  1.000 41.51859 ? 11  ARG C CD  1 
ATOM   2373 N NE  . ARG C 1 11  ? 4.86490   30.80224  -1.14517  1.000 30.85225 ? 11  ARG C NE  1 
ATOM   2374 C CZ  . ARG C 1 11  ? 5.03378   32.11305  -1.13432  1.000 27.28954 ? 11  ARG C CZ  1 
ATOM   2375 N NH1 . ARG C 1 11  ? 4.13457   32.91041  -0.58933  1.000 35.33499 ? 11  ARG C NH1 1 
ATOM   2376 N NH2 . ARG C 1 11  ? 6.13615   32.63559  -1.66888  1.000 26.39530 ? 11  ARG C NH2 1 
ATOM   2377 N N   . LEU C 1 12  ? -1.29047  30.76529  -0.31766  1.000 35.93939 ? 12  LEU C N   1 
ATOM   2378 C CA  . LEU C 1 12  ? -2.12496  31.87062  -0.76308  1.000 36.02396 ? 12  LEU C CA  1 
ATOM   2379 C C   . LEU C 1 12  ? -3.33710  31.98915  0.14078   1.000 37.74205 ? 12  LEU C C   1 
ATOM   2380 O O   . LEU C 1 12  ? -4.10790  31.03255  0.28000   1.000 41.34831 ? 12  LEU C O   1 
ATOM   2381 C CB  . LEU C 1 12  ? -2.57750  31.68511  -2.21607  1.000 38.30880 ? 12  LEU C CB  1 
ATOM   2382 C CG  . LEU C 1 12  ? -1.59602  32.01189  -3.34275  1.000 34.89162 ? 12  LEU C CG  1 
ATOM   2383 C CD1 . LEU C 1 12  ? -0.48426  30.98487  -3.42574  1.000 41.16007 ? 12  LEU C CD1 1 
ATOM   2384 C CD2 . LEU C 1 12  ? -2.33592  32.10515  -4.67637  1.000 43.22610 ? 12  LEU C CD2 1 
ATOM   2385 N N   . THR C 1 13  ? -3.51477  33.17039  0.73102   1.000 36.63935 ? 13  THR C N   1 
ATOM   2386 C CA  . THR C 1 13  ? -4.74521  33.49952  1.43091   1.000 40.97887 ? 13  THR C CA  1 
ATOM   2387 C C   . THR C 1 13  ? -5.86771  33.63169  0.39975   1.000 37.84111 ? 13  THR C C   1 
ATOM   2388 O O   . THR C 1 13  ? -5.62229  33.55476  -0.80651  1.000 35.87325 ? 13  THR C O   1 
ATOM   2389 C CB  . THR C 1 13  ? -4.55811  34.78719  2.24501   1.000 37.77056 ? 13  THR C CB  1 
ATOM   2390 O OG1 . THR C 1 13  ? -4.03476  35.82913  1.40254   1.000 40.57070 ? 13  THR C OG1 1 
ATOM   2391 C CG2 . THR C 1 13  ? -3.61193  34.55594  3.42328   1.000 30.95030 ? 13  THR C CG2 1 
ATOM   2392 N N   . PRO C 1 14  ? -7.12194  33.80078  0.83744   1.000 33.33009 ? 14  PRO C N   1 
ATOM   2393 C CA  . PRO C 1 14  ? -8.16727  34.17970  -0.13128  1.000 35.78122 ? 14  PRO C CA  1 
ATOM   2394 C C   . PRO C 1 14  ? -7.79604  35.40792  -0.94680  1.000 35.64472 ? 14  PRO C C   1 
ATOM   2395 O O   . PRO C 1 14  ? -7.98811  35.43344  -2.17381  1.000 34.25554 ? 14  PRO C O   1 
ATOM   2396 C CB  . PRO C 1 14  ? -9.38553  34.43424  0.75906   1.000 35.05063 ? 14  PRO C CB  1 
ATOM   2397 C CG  . PRO C 1 14  ? -9.15515  33.57824  1.94509   1.000 31.05943 ? 14  PRO C CG  1 
ATOM   2398 C CD  . PRO C 1 14  ? -7.68032  33.54417  2.17523   1.000 29.47345 ? 14  PRO C CD  1 
ATOM   2399 N N   . SER C 1 15  ? -7.22050  36.41787  -0.28660  1.000 35.51770 ? 15  SER C N   1 
ATOM   2400 C CA  . SER C 1 15  ? -6.85802  37.65905  -0.96278  1.000 38.36223 ? 15  SER C CA  1 
ATOM   2401 C C   . SER C 1 15  ? -5.72966  37.45101  -1.96574  1.000 39.34974 ? 15  SER C C   1 
ATOM   2402 O O   . SER C 1 15  ? -5.68003  38.14139  -2.99348  1.000 31.35825 ? 15  SER C O   1 
ATOM   2403 C CB  . SER C 1 15  ? -6.45511  38.71631  0.06492   1.000 34.92053 ? 15  SER C CB  1 
ATOM   2404 O OG  . SER C 1 15  ? -7.42716  38.84447  1.08685   1.000 50.43141 ? 15  SER C OG  1 
ATOM   2405 N N   . ALA C 1 16  ? -4.81218  36.52264  -1.67700  1.000 31.19874 ? 16  ALA C N   1 
ATOM   2406 C CA  . ALA C 1 16  ? -3.69608  36.26456  -2.57085  1.000 30.71653 ? 16  ALA C CA  1 
ATOM   2407 C C   . ALA C 1 16  ? -4.12309  35.45350  -3.79571  1.000 38.97270 ? 16  ALA C C   1 
ATOM   2408 O O   . ALA C 1 16  ? -3.54593  35.61651  -4.88365  1.000 33.04299 ? 16  ALA C O   1 
ATOM   2409 C CB  . ALA C 1 16  ? -2.58910  35.54675  -1.79852  1.000 31.60137 ? 16  ALA C CB  1 
ATOM   2410 N N   . LYS C 1 17  ? -5.13009  34.58607  -3.63648  1.000 33.82118 ? 17  LYS C N   1 
ATOM   2411 C CA  . LYS C 1 17  ? -5.63401  33.81120  -4.76623  1.000 38.97891 ? 17  LYS C CA  1 
ATOM   2412 C C   . LYS C 1 17  ? -6.33536  34.70465  -5.78073  1.000 33.14146 ? 17  LYS C C   1 
ATOM   2413 O O   . LYS C 1 17  ? -6.13953  34.54595  -6.98831  1.000 34.03427 ? 17  LYS C O   1 
ATOM   2414 C CB  . LYS C 1 17  ? -6.58195  32.71570  -4.27509  1.000 35.50490 ? 17  LYS C CB  1 
ATOM   2415 C CG  . LYS C 1 17  ? -5.89624  31.44509  -3.82667  1.000 32.49826 ? 17  LYS C CG  1 
ATOM   2416 C CD  . LYS C 1 17  ? -6.61901  30.84172  -2.63750  1.000 36.20442 ? 17  LYS C CD  1 
ATOM   2417 C CE  . LYS C 1 17  ? -6.22896  29.39029  -2.45405  1.000 35.29962 ? 17  LYS C CE  1 
ATOM   2418 N NZ  . LYS C 1 17  ? -6.35833  28.94658  -1.04209  1.000 35.83519 ? 17  LYS C NZ  1 
ATOM   2419 N N   . HIS C 1 18  ? -7.16869  35.63569  -5.30763  1.000 34.36360 ? 18  HIS C N   1 
ATOM   2420 C CA  . HIS C 1 18  ? -7.82411  36.58306  -6.20828  1.000 38.42778 ? 18  HIS C CA  1 
ATOM   2421 C C   . HIS C 1 18  ? -6.79318  37.45561  -6.92711  1.000 34.77950 ? 18  HIS C C   1 
ATOM   2422 O O   . HIS C 1 18  ? -6.93669  37.75679  -8.11857  1.000 30.36410 ? 18  HIS C O   1 
ATOM   2423 C CB  . HIS C 1 18  ? -8.82607  37.43180  -5.41240  1.000 32.57474 ? 18  HIS C CB  1 
ATOM   2424 C CG  . HIS C 1 18  ? -9.76669  38.23849  -6.26139  1.000 43.46621 ? 18  HIS C CG  1 
ATOM   2425 N ND1 . HIS C 1 18  ? -10.04677 39.56424  -6.00741  1.000 35.41067 ? 18  HIS C ND1 1 
ATOM   2426 C CD2 . HIS C 1 18  ? -10.49705 37.90509  -7.35452  1.000 42.77024 ? 18  HIS C CD2 1 
ATOM   2427 C CE1 . HIS C 1 18  ? -10.89929 40.01382  -6.91376  1.000 38.94835 ? 18  HIS C CE1 1 
ATOM   2428 N NE2 . HIS C 1 18  ? -11.19057 39.02811  -7.74040  1.000 43.16490 ? 18  HIS C NE2 1 
ATOM   2429 N N   . ALA C 1 19  ? -5.73697  37.85761  -6.21442  1.000 36.45438 ? 19  ALA C N   1 
ATOM   2430 C CA  . ALA C 1 19  ? -4.64679  38.59194  -6.84229  1.000 31.58947 ? 19  ALA C CA  1 
ATOM   2431 C C   . ALA C 1 19  ? -4.00292  37.77373  -7.95087  1.000 31.89865 ? 19  ALA C C   1 
ATOM   2432 O O   . ALA C 1 19  ? -3.59627  38.31809  -8.98456  1.000 39.05213 ? 19  ALA C O   1 
ATOM   2433 C CB  . ALA C 1 19  ? -3.60158  38.97416  -5.79500  1.000 32.00522 ? 19  ALA C CB  1 
ATOM   2434 N N   . VAL C 1 20  ? -3.89817  36.46498  -7.75431  1.000 26.34735 ? 20  VAL C N   1 
ATOM   2435 C CA  . VAL C 1 20  ? -3.25581  35.61906  -8.75252  1.000 29.42605 ? 20  VAL C CA  1 
ATOM   2436 C C   . VAL C 1 20  ? -4.17449  35.41375  -9.95496  1.000 32.30807 ? 20  VAL C C   1 
ATOM   2437 O O   . VAL C 1 20  ? -3.77172  35.61863  -11.10620 1.000 29.66806 ? 20  VAL C O   1 
ATOM   2438 C CB  . VAL C 1 20  ? -2.82304  34.29433  -8.10672  1.000 29.46445 ? 20  VAL C CB  1 
ATOM   2439 C CG1 . VAL C 1 20  ? -2.63019  33.22476  -9.14961  1.000 24.07490 ? 20  VAL C CG1 1 
ATOM   2440 C CG2 . VAL C 1 20  ? -1.53762  34.52814  -7.29149  1.000 26.01424 ? 20  VAL C CG2 1 
ATOM   2441 N N   . ALA C 1 21  ? -5.43156  35.04546  -9.69777  1.000 35.62260 ? 21  ALA C N   1 
ATOM   2442 C CA  . ALA C 1 21  ? -6.42593  34.92493  -10.75889 1.000 32.19833 ? 21  ALA C CA  1 
ATOM   2443 C C   . ALA C 1 21  ? -6.54234  36.20834  -11.56526 1.000 28.68315 ? 21  ALA C C   1 
ATOM   2444 O O   . ALA C 1 21  ? -6.55664  36.17207  -12.79430 1.000 39.14791 ? 21  ALA C O   1 
ATOM   2445 C CB  . ALA C 1 21  ? -7.78296  34.54771  -10.16275 1.000 34.52510 ? 21  ALA C CB  1 
ATOM   2446 N N   . LYS C 1 22  ? -6.62886  37.35698  -10.88947 1.000 34.45738 ? 22  LYS C N   1 
ATOM   2447 C CA  . LYS C 1 22  ? -6.82132  38.62579  -11.59618 1.000 33.27185 ? 22  LYS C CA  1 
ATOM   2448 C C   . LYS C 1 22  ? -5.64143  38.93819  -12.50292 1.000 26.76720 ? 22  LYS C C   1 
ATOM   2449 O O   . LYS C 1 22  ? -5.81725  39.47653  -13.59895 1.000 36.58875 ? 22  LYS C O   1 
ATOM   2450 C CB  . LYS C 1 22  ? -7.03732  39.76579  -10.59361 1.000 40.56908 ? 22  LYS C CB  1 
ATOM   2451 C CG  . LYS C 1 22  ? -8.18737  40.74612  -10.92755 1.000 47.28034 ? 22  LYS C CG  1 
ATOM   2452 C CD  . LYS C 1 22  ? -7.79931  41.83072  -11.94478 1.000 39.29845 ? 22  LYS C CD  1 
ATOM   2453 C CE  . LYS C 1 22  ? -8.98724  42.75197  -12.25313 1.000 43.23867 ? 22  LYS C CE  1 
ATOM   2454 N NZ  . LYS C 1 22  ? -8.68219  43.84590  -13.22815 1.000 29.33045 ? 22  LYS C NZ  1 
ATOM   2455 N N   . ALA C 1 23  ? -4.43060  38.59290  -12.07350 1.000 31.13099 ? 23  ALA C N   1 
ATOM   2456 C CA  . ALA C 1 23  ? -3.27760  38.78404  -12.94412 1.000 34.26157 ? 23  ALA C CA  1 
ATOM   2457 C C   . ALA C 1 23  ? -3.29966  37.79838  -14.11423 1.000 34.83830 ? 23  ALA C C   1 
ATOM   2458 O O   . ALA C 1 23  ? -3.09775  38.19589  -15.26854 1.000 31.41874 ? 23  ALA C O   1 
ATOM   2459 C CB  . ALA C 1 23  ? -1.98756  38.65155  -12.13391 1.000 27.04028 ? 23  ALA C CB  1 
ATOM   2460 N N   . ILE C 1 24  ? -3.54885  36.51187  -13.83211 1.000 28.61226 ? 24  ILE C N   1 
ATOM   2461 C CA  . ILE C 1 24  ? -3.66432  35.51110  -14.88881 1.000 32.06134 ? 24  ILE C CA  1 
ATOM   2462 C C   . ILE C 1 24  ? -4.75050  35.89926  -15.89295 1.000 33.96482 ? 24  ILE C C   1 
ATOM   2463 O O   . ILE C 1 24  ? -4.51058  35.92621  -17.10425 1.000 33.95758 ? 24  ILE C O   1 
ATOM   2464 C CB  . ILE C 1 24  ? -3.92486  34.11380  -14.29607 1.000 31.34878 ? 24  ILE C CB  1 
ATOM   2465 C CG1 . ILE C 1 24  ? -2.62061  33.47666  -13.78306 1.000 31.21218 ? 24  ILE C CG1 1 
ATOM   2466 C CG2 . ILE C 1 24  ? -4.55048  33.22730  -15.36309 1.000 26.91003 ? 24  ILE C CG2 1 
ATOM   2467 C CD1 . ILE C 1 24  ? -2.82417  32.21694  -12.87582 1.000 18.31134 ? 24  ILE C CD1 1 
ATOM   2468 N N   . THR C 1 25  ? -5.96019  36.20219  -15.41557 1.000 31.31696 ? 25  THR C N   1 
ATOM   2469 C CA  . THR C 1 25  ? -7.05333  36.47333  -16.34668 1.000 28.50134 ? 25  THR C CA  1 
ATOM   2470 C C   . THR C 1 25  ? -6.80188  37.74474  -17.14343 1.000 31.77496 ? 25  THR C C   1 
ATOM   2471 O O   . THR C 1 25  ? -7.04855  37.79026  -18.34824 1.000 34.60515 ? 25  THR C O   1 
ATOM   2472 C CB  . THR C 1 25  ? -8.37649  36.58303  -15.60395 1.000 32.75229 ? 25  THR C CB  1 
ATOM   2473 O OG1 . THR C 1 25  ? -8.42223  35.57344  -14.60250 1.000 37.24053 ? 25  THR C OG1 1 
ATOM   2474 C CG2 . THR C 1 25  ? -9.59282  36.42744  -16.57793 1.000 44.96429 ? 25  THR C CG2 1 
ATOM   2475 N N   . ASP C 1 26  ? -6.32070  38.79876  -16.48872 1.000 32.04501 ? 26  ASP C N   1 
ATOM   2476 C CA  . ASP C 1 26  ? -6.07423  40.02668  -17.22865 1.000 35.22011 ? 26  ASP C CA  1 
ATOM   2477 C C   . ASP C 1 26  ? -5.01760  39.80159  -18.29635 1.000 31.34320 ? 26  ASP C C   1 
ATOM   2478 O O   . ASP C 1 26  ? -5.19867  40.19532  -19.45526 1.000 27.90102 ? 26  ASP C O   1 
ATOM   2479 C CB  . ASP C 1 26  ? -5.66505  41.15468  -16.28255 1.000 34.28062 ? 26  ASP C CB  1 
ATOM   2480 C CG  . ASP C 1 26  ? -6.80967  41.63030  -15.42480 1.000 30.01236 ? 26  ASP C CG  1 
ATOM   2481 O OD1 . ASP C 1 26  ? -7.92544  41.08949  -15.55018 1.000 34.97929 ? 26  ASP C OD1 1 
ATOM   2482 O OD2 . ASP C 1 26  ? -6.59306  42.54848  -14.62768 1.000 34.91194 ? 26  ASP C OD2 1 
ATOM   2483 N N   . ALA C 1 27  ? -3.92428  39.12442  -17.92897 1.000 30.66244 ? 27  ALA C N   1 
ATOM   2484 C CA  . ALA C 1 27  ? -2.88429  38.80715  -18.90125 1.000 30.52804 ? 27  ALA C CA  1 
ATOM   2485 C C   . ALA C 1 27  ? -3.43971  38.00506  -20.07964 1.000 29.39938 ? 27  ALA C C   1 
ATOM   2486 O O   . ALA C 1 27  ? -3.05464  38.23320  -21.23045 1.000 30.51540 ? 27  ALA C O   1 
ATOM   2487 C CB  . ALA C 1 27  ? -1.74803  38.05094  -18.21830 1.000 32.28165 ? 27  ALA C CB  1 
ATOM   2488 N N   . HIS C 1 28  ? -4.35092  37.06884  -19.81654 1.000 26.60582 ? 28  HIS C N   1 
ATOM   2489 C CA  . HIS C 1 28  ? -4.93539  36.30864  -20.91393 1.000 30.32051 ? 28  HIS C CA  1 
ATOM   2490 C C   . HIS C 1 28  ? -5.87123  37.16329  -21.74870 1.000 29.98979 ? 28  HIS C C   1 
ATOM   2491 O O   . HIS C 1 28  ? -5.93907  36.98830  -22.96936 1.000 28.39435 ? 28  HIS C O   1 
ATOM   2492 C CB  . HIS C 1 28  ? -5.68108  35.08282  -20.38895 1.000 31.50949 ? 28  HIS C CB  1 
ATOM   2493 C CG  . HIS C 1 28  ? -6.17099  34.17202  -21.47318 1.000 31.34127 ? 28  HIS C CG  1 
ATOM   2494 N ND1 . HIS C 1 28  ? -5.33265  33.34235  -22.18468 1.000 26.21517 ? 28  HIS C ND1 1 
ATOM   2495 C CD2 . HIS C 1 28  ? -7.41231  33.97587  -21.98001 1.000 31.92659 ? 28  HIS C CD2 1 
ATOM   2496 C CE1 . HIS C 1 28  ? -6.03717  32.66283  -23.07136 1.000 24.54215 ? 28  HIS C CE1 1 
ATOM   2497 N NE2 . HIS C 1 28  ? -7.30084  33.03324  -22.97116 1.000 18.96279 ? 28  HIS C NE2 1 
ATOM   2498 N N   . ARG C 1 29  ? -6.59725  38.08512  -21.10980 1.000 32.90311 ? 29  ARG C N   1 
ATOM   2499 C CA  . ARG C 1 29  ? -7.51984  38.95479  -21.83543 1.000 34.28895 ? 29  ARG C CA  1 
ATOM   2500 C C   . ARG C 1 29  ? -6.77628  39.96981  -22.69734 1.000 33.66703 ? 29  ARG C C   1 
ATOM   2501 O O   . ARG C 1 29  ? -7.17756  40.23944  -23.83325 1.000 33.23939 ? 29  ARG C O   1 
ATOM   2502 C CB  . ARG C 1 29  ? -8.44728  39.67260  -20.85352 1.000 31.19212 ? 29  ARG C CB  1 
ATOM   2503 C CG  . ARG C 1 29  ? -9.36410  40.68583  -21.51177 1.000 37.52113 ? 29  ARG C CG  1 
ATOM   2504 C CD  . ARG C 1 29  ? -8.90189  42.11813  -21.30218 1.000 42.20230 ? 29  ARG C CD  1 
ATOM   2505 N NE  . ARG C 1 29  ? -9.44145  43.02679  -22.31174 1.000 58.00152 ? 29  ARG C NE  1 
ATOM   2506 C CZ  . ARG C 1 29  ? -9.61282  44.33410  -22.14166 1.000 55.52639 ? 29  ARG C CZ  1 
ATOM   2507 N NH1 . ARG C 1 29  ? -9.36754  44.91853  -20.98010 1.000 55.69525 ? 29  ARG C NH1 1 
ATOM   2508 N NH2 . ARG C 1 29  ? -10.04486 45.07245  -23.16178 1.000 44.70482 ? 29  ARG C NH2 1 
ATOM   2509 N N   . GLY C 1 30  ? -5.68385  40.53729  -22.17866 1.000 38.15266 ? 30  GLY C N   1 
ATOM   2510 C CA  . GLY C 1 30  ? -4.98449  41.59386  -22.88823 1.000 35.71465 ? 30  GLY C CA  1 
ATOM   2511 C C   . GLY C 1 30  ? -4.14863  41.13307  -24.05900 1.000 35.45001 ? 30  GLY C C   1 
ATOM   2512 O O   . GLY C 1 30  ? -3.89262  41.92510  -24.97002 1.000 38.95182 ? 30  GLY C O   1 
ATOM   2513 N N   . LEU C 1 31  ? -3.71295  39.87688  -24.07150 1.000 28.86961 ? 31  LEU C N   1 
ATOM   2514 C CA  . LEU C 1 31  ? -2.91600  39.41351  -25.19556 1.000 28.54954 ? 31  LEU C CA  1 
ATOM   2515 C C   . LEU C 1 31  ? -3.70329  38.58024  -26.20159 1.000 27.57409 ? 31  LEU C C   1 
ATOM   2516 O O   . LEU C 1 31  ? -3.22338  38.37207  -27.31885 1.000 28.77282 ? 31  LEU C O   1 
ATOM   2517 C CB  . LEU C 1 31  ? -1.69882  38.63822  -24.68748 1.000 24.87129 ? 31  LEU C CB  1 
ATOM   2518 C CG  . LEU C 1 31  ? -0.77244  39.60081  -23.92557 1.000 30.98371 ? 31  LEU C CG  1 
ATOM   2519 C CD1 . LEU C 1 31  ? 0.32631   38.90372  -23.10157 1.000 25.15718 ? 31  LEU C CD1 1 
ATOM   2520 C CD2 . LEU C 1 31  ? -0.16298  40.60802  -24.88685 1.000 23.30961 ? 31  LEU C CD2 1 
ATOM   2521 N N   . THR C 1 32  ? -4.90983  38.13275  -25.86807 1.000 31.29171 ? 32  THR C N   1 
ATOM   2522 C CA  . THR C 1 32  ? -5.70896  37.40279  -26.84298 1.000 28.75011 ? 32  THR C CA  1 
ATOM   2523 C C   . THR C 1 32  ? -6.99436  38.11474  -27.23702 1.000 30.11467 ? 32  THR C C   1 
ATOM   2524 O O   . THR C 1 32  ? -7.54077  37.81720  -28.30279 1.000 34.17652 ? 32  THR C O   1 
ATOM   2525 C CB  . THR C 1 32  ? -6.06046  36.00703  -26.31372 1.000 20.99004 ? 32  THR C CB  1 
ATOM   2526 O OG1 . THR C 1 32  ? -7.04206  36.12800  -25.27668 1.000 26.31912 ? 32  THR C OG1 1 
ATOM   2527 C CG2 . THR C 1 32  ? -4.81829  35.33407  -25.76139 1.000 22.95333 ? 32  THR C CG2 1 
ATOM   2528 N N   . GLY C 1 33  ? -7.47106  39.05902  -26.43013 1.000 32.42258 ? 33  GLY C N   1 
ATOM   2529 C CA  . GLY C 1 33  ? -8.77334  39.64495  -26.64460 1.000 25.59257 ? 33  GLY C CA  1 
ATOM   2530 C C   . GLY C 1 33  ? -9.92517  38.79550  -26.16393 1.000 34.11503 ? 33  GLY C C   1 
ATOM   2531 O O   . GLY C 1 33  ? -11.08396 39.17111  -26.38572 1.000 44.98610 ? 33  GLY C O   1 
ATOM   2532 N N   . THR C 1 34  ? -9.65498  37.65445  -25.53065 1.000 34.04364 ? 34  THR C N   1 
ATOM   2533 C CA  . THR C 1 34  ? -10.73448 36.84810  -24.98003 1.000 33.63728 ? 34  THR C CA  1 
ATOM   2534 C C   . THR C 1 34  ? -11.48158 37.64155  -23.91992 1.000 39.17247 ? 34  THR C C   1 
ATOM   2535 O O   . THR C 1 34  ? -10.87117 38.20756  -23.00528 1.000 38.23977 ? 34  THR C O   1 
ATOM   2536 C CB  . THR C 1 34  ? -10.19686 35.55163  -24.37297 1.000 32.16563 ? 34  THR C CB  1 
ATOM   2537 O OG1 . THR C 1 34  ? -9.38857  34.86709  -25.33163 1.000 28.22540 ? 34  THR C OG1 1 
ATOM   2538 C CG2 . THR C 1 34  ? -11.34296 34.63875  -23.96697 1.000 28.86899 ? 34  THR C CG2 1 
ATOM   2539 N N   . GLN C 1 35  ? -12.80469 37.69012  -24.04898 1.000 38.13607 ? 35  GLN C N   1 
ATOM   2540 C CA  . GLN C 1 35  ? -13.59219 38.39630  -23.05885 1.000 37.49269 ? 35  GLN C CA  1 
ATOM   2541 C C   . GLN C 1 35  ? -13.50697 37.68301  -21.71392 1.000 42.37177 ? 35  GLN C C   1 
ATOM   2542 O O   . GLN C 1 35  ? -13.21473 36.48254  -21.61674 1.000 37.12374 ? 35  GLN C O   1 
ATOM   2543 C CB  . GLN C 1 35  ? -15.03934 38.53101  -23.51118 1.000 40.33676 ? 35  GLN C CB  1 
ATOM   2544 C CG  . GLN C 1 35  ? -15.58859 37.26336  -24.08940 1.000 45.71026 ? 35  GLN C CG  1 
ATOM   2545 C CD  . GLN C 1 35  ? -16.80456 37.51443  -24.93299 1.000 46.22747 ? 35  GLN C CD  1 
ATOM   2546 O OE1 . GLN C 1 35  ? -17.27924 36.62606  -25.63414 1.000 43.46976 ? 35  GLN C OE1 1 
ATOM   2547 N NE2 . GLN C 1 35  ? -17.31979 38.73417  -24.87386 1.000 47.45008 ? 35  GLN C NE2 1 
ATOM   2548 N N   . HIS C 1 36  ? -13.79829 38.45208  -20.66839 1.000 43.64105 ? 36  HIS C N   1 
ATOM   2549 C CA  . HIS C 1 36  ? -13.26664 38.15060  -19.34762 1.000 45.92563 ? 36  HIS C CA  1 
ATOM   2550 C C   . HIS C 1 36  ? -13.80755 36.83433  -18.81064 1.000 45.55570 ? 36  HIS C C   1 
ATOM   2551 O O   . HIS C 1 36  ? -13.05286 36.01264  -18.27865 1.000 41.75248 ? 36  HIS C O   1 
ATOM   2552 C CB  . HIS C 1 36  ? -13.58992 39.29872  -18.39321 1.000 43.43077 ? 36  HIS C CB  1 
ATOM   2553 C CG  . HIS C 1 36  ? -12.45747 39.65531  -17.48272 1.000 42.98810 ? 36  HIS C CG  1 
ATOM   2554 N ND1 . HIS C 1 36  ? -11.97349 38.78169  -16.53027 1.000 46.96966 ? 36  HIS C ND1 1 
ATOM   2555 C CD2 . HIS C 1 36  ? -11.69817 40.77694  -17.39789 1.000 44.62217 ? 36  HIS C CD2 1 
ATOM   2556 C CE1 . HIS C 1 36  ? -10.98127 39.36001  -15.87380 1.000 45.56339 ? 36  HIS C CE1 1 
ATOM   2557 N NE2 . HIS C 1 36  ? -10.79079 40.56499  -16.38534 1.000 55.91054 ? 36  HIS C NE2 1 
ATOM   2558 N N   . PHE C 1 37  ? -15.11612 36.61337  -18.94462 1.000 45.00921 ? 37  PHE C N   1 
ATOM   2559 C CA  . PHE C 1 37  ? -15.75680 35.47409  -18.29587 1.000 40.84272 ? 37  PHE C CA  1 
ATOM   2560 C C   . PHE C 1 37  ? -15.26273 34.13219  -18.82426 1.000 36.55505 ? 37  PHE C C   1 
ATOM   2561 O O   . PHE C 1 37  ? -15.59158 33.10178  -18.23609 1.000 37.55964 ? 37  PHE C O   1 
ATOM   2562 C CB  . PHE C 1 37  ? -17.28096 35.56928  -18.44401 1.000 40.02600 ? 37  PHE C CB  1 
ATOM   2563 C CG  . PHE C 1 37  ? -17.73825 36.19178  -19.74289 1.000 41.03830 ? 37  PHE C CG  1 
ATOM   2564 C CD1 . PHE C 1 37  ? -17.88223 35.42907  -20.89015 1.000 41.33419 ? 37  PHE C CD1 1 
ATOM   2565 C CD2 . PHE C 1 37  ? -18.03908 37.54407  -19.81229 1.000 47.67216 ? 37  PHE C CD2 1 
ATOM   2566 C CE1 . PHE C 1 37  ? -18.30933 36.01256  -22.08315 1.000 46.67064 ? 37  PHE C CE1 1 
ATOM   2567 C CE2 . PHE C 1 37  ? -18.46431 38.13123  -20.99767 1.000 44.67342 ? 37  PHE C CE2 1 
ATOM   2568 C CZ  . PHE C 1 37  ? -18.60125 37.36445  -22.13225 1.000 38.37674 ? 37  PHE C CZ  1 
ATOM   2569 N N   . LEU C 1 38  ? -14.47193 34.11089  -19.89496 1.000 39.27304 ? 38  LEU C N   1 
ATOM   2570 C CA  . LEU C 1 38  ? -14.02205 32.85937  -20.49321 1.000 31.08779 ? 38  LEU C CA  1 
ATOM   2571 C C   . LEU C 1 38  ? -12.73626 32.30653  -19.89256 1.000 26.01727 ? 38  LEU C C   1 
ATOM   2572 O O   . LEU C 1 38  ? -12.33937 31.19209  -20.24932 1.000 32.60309 ? 38  LEU C O   1 
ATOM   2573 C CB  . LEU C 1 38  ? -13.82396 33.03442  -22.00260 1.000 24.76907 ? 38  LEU C CB  1 
ATOM   2574 C CG  . LEU C 1 38  ? -15.07174 32.87698  -22.84446 1.000 27.48216 ? 38  LEU C CG  1 
ATOM   2575 C CD1 . LEU C 1 38  ? -14.69117 32.42495  -24.23285 1.000 27.14883 ? 38  LEU C CD1 1 
ATOM   2576 C CD2 . LEU C 1 38  ? -16.02347 31.89552  -22.19652 1.000 16.28260 ? 38  LEU C CD2 1 
ATOM   2577 N N   . ALA C 1 39  ? -12.05972 33.03750  -19.01880 1.000 30.51723 ? 39  ALA C N   1 
ATOM   2578 C CA  . ALA C 1 39  ? -10.76531 32.59796  -18.49629 1.000 32.40389 ? 39  ALA C CA  1 
ATOM   2579 C C   . ALA C 1 39  ? -10.93296 32.14297  -17.04896 1.000 29.40217 ? 39  ALA C C   1 
ATOM   2580 O O   . ALA C 1 39  ? -10.90105 32.95047  -16.12099 1.000 34.73874 ? 39  ALA C O   1 
ATOM   2581 C CB  . ALA C 1 39  ? -9.72334  33.70068  -18.62072 1.000 31.92722 ? 39  ALA C CB  1 
ATOM   2582 N N   . GLN C 1 40  ? -11.10355 30.83355  -16.87191 1.000 30.10720 ? 40  GLN C N   1 
ATOM   2583 C CA  . GLN C 1 40  ? -11.19429 30.22127  -15.55570 1.000 20.12943 ? 40  GLN C CA  1 
ATOM   2584 C C   . GLN C 1 40  ? -9.80683  30.03167  -14.95854 1.000 19.52674 ? 40  GLN C C   1 
ATOM   2585 O O   . GLN C 1 40  ? -8.86130  29.67648  -15.65887 1.000 18.07046 ? 40  GLN C O   1 
ATOM   2586 C CB  . GLN C 1 40  ? -11.89292 28.86297  -15.64799 1.000 21.80945 ? 40  GLN C CB  1 
ATOM   2587 C CG  . GLN C 1 40  ? -11.63784 27.96685  -14.44225 1.000 19.31501 ? 40  GLN C CG  1 
ATOM   2588 C CD  . GLN C 1 40  ? -12.39636 26.66803  -14.49006 1.000 18.13909 ? 40  GLN C CD  1 
ATOM   2589 O OE1 . GLN C 1 40  ? -12.15911 25.78366  -13.67698 1.000 20.35580 ? 40  GLN C OE1 1 
ATOM   2590 N NE2 . GLN C 1 40  ? -13.33468 26.55392  -15.42242 1.000 15.56442 ? 40  GLN C NE2 1 
ATOM   2591 N N   . VAL C 1 41  ? -9.69677  30.25306  -13.65045 1.000 24.05511 ? 41  VAL C N   1 
ATOM   2592 C CA  . VAL C 1 41  ? -8.47805  29.99410  -12.89142 1.000 25.77193 ? 41  VAL C CA  1 
ATOM   2593 C C   . VAL C 1 41  ? -8.83174  29.01339  -11.78030 1.000 22.37099 ? 41  VAL C C   1 
ATOM   2594 O O   . VAL C 1 41  ? -9.75445  29.25713  -11.00111 1.000 29.78754 ? 41  VAL C O   1 
ATOM   2595 C CB  . VAL C 1 41  ? -7.86254  31.29439  -12.33935 1.000 26.51223 ? 41  VAL C CB  1 
ATOM   2596 C CG1 . VAL C 1 41  ? -6.59650  30.99296  -11.53336 1.000 24.34861 ? 41  VAL C CG1 1 
ATOM   2597 C CG2 . VAL C 1 41  ? -7.55666  32.28693  -13.50504 1.000 16.74093 ? 41  VAL C CG2 1 
ATOM   2598 N N   . ASN C 1 42  ? -8.11904  27.89941  -11.71547 1.000 22.66921 ? 42  ASN C N   1 
ATOM   2599 C CA  . ASN C 1 42  ? -8.52922  26.75499  -10.90009 1.000 21.24021 ? 42  ASN C CA  1 
ATOM   2600 C C   . ASN C 1 42  ? -7.36596  26.40201  -9.97520  1.000 21.36236 ? 42  ASN C C   1 
ATOM   2601 O O   . ASN C 1 42  ? -6.35745  25.83628  -10.40988 1.000 18.18680 ? 42  ASN C O   1 
ATOM   2602 C CB  . ASN C 1 42  ? -8.95021  25.59048  -11.80029 1.000 20.83387 ? 42  ASN C CB  1 
ATOM   2603 C CG  . ASN C 1 42  ? -9.69446  24.50001  -11.05440 1.000 22.54029 ? 42  ASN C CG  1 
ATOM   2604 O OD1 . ASN C 1 42  ? -9.22923  24.02456  -10.02873 1.000 20.56384 ? 42  ASN C OD1 1 
ATOM   2605 N ND2 . ASN C 1 42  ? -10.84436 24.08062  -11.58349 1.000 16.22880 ? 42  ASN C ND2 1 
ATOM   2606 N N   . PHE C 1 43  ? -7.49781  26.77528  -8.70631  1.000 19.87053 ? 43  PHE C N   1 
ATOM   2607 C CA  . PHE C 1 43  ? -6.42714  26.58641  -7.74107  1.000 22.45084 ? 43  PHE C CA  1 
ATOM   2608 C C   . PHE C 1 43  ? -6.48448  25.17128  -7.19130  1.000 26.26431 ? 43  PHE C C   1 
ATOM   2609 O O   . PHE C 1 43  ? -7.55820  24.66084  -6.85788  1.000 30.11126 ? 43  PHE C O   1 
ATOM   2610 C CB  . PHE C 1 43  ? -6.50658  27.62112  -6.60878  1.000 25.63555 ? 43  PHE C CB  1 
ATOM   2611 C CG  . PHE C 1 43  ? -6.13990  29.00754  -7.04583  1.000 25.14114 ? 43  PHE C CG  1 
ATOM   2612 C CD1 . PHE C 1 43  ? -4.81165  29.35945  -7.23384  1.000 22.92297 ? 43  PHE C CD1 1 
ATOM   2613 C CD2 . PHE C 1 43  ? -7.11689  29.94475  -7.31125  1.000 26.73093 ? 43  PHE C CD2 1 
ATOM   2614 C CE1 . PHE C 1 43  ? -4.47107  30.61281  -7.67823  1.000 20.14166 ? 43  PHE C CE1 1 
ATOM   2615 C CE2 . PHE C 1 43  ? -6.77337  31.20252  -7.74658  1.000 27.20011 ? 43  PHE C CE2 1 
ATOM   2616 C CZ  . PHE C 1 43  ? -5.45038  31.53437  -7.92747  1.000 25.44428 ? 43  PHE C CZ  1 
ATOM   2617 N N   . GLN C 1 44  ? -5.32346  24.53627  -7.12969  1.000 20.77849 ? 44  GLN C N   1 
ATOM   2618 C CA  . GLN C 1 44  ? -5.19285  23.14307  -6.73316  1.000 25.28237 ? 44  GLN C CA  1 
ATOM   2619 C C   . GLN C 1 44  ? -4.10752  23.06677  -5.67067  1.000 20.72453 ? 44  GLN C C   1 
ATOM   2620 O O   . GLN C 1 44  ? -2.92537  23.24084  -5.97203  1.000 23.76572 ? 44  GLN C O   1 
ATOM   2621 C CB  . GLN C 1 44  ? -4.86858  22.27121  -7.94274  1.000 23.90718 ? 44  GLN C CB  1 
ATOM   2622 C CG  . GLN C 1 44  ? -5.99224  22.21709  -8.95986  1.000 19.68058 ? 44  GLN C CG  1 
ATOM   2623 C CD  . GLN C 1 44  ? -7.27843  21.56104  -8.43734  1.000 23.33040 ? 44  GLN C CD  1 
ATOM   2624 O OE1 . GLN C 1 44  ? -7.34630  20.35358  -8.26117  1.000 31.34651 ? 44  GLN C OE1 1 
ATOM   2625 N NE2 . GLN C 1 44  ? -8.30237  22.36163  -8.21654  1.000 25.71487 ? 44  GLN C NE2 1 
ATOM   2626 N N   . GLU C 1 45  ? -4.52029  22.83369  -4.43419  1.000 19.90188 ? 45  GLU C N   1 
ATOM   2627 C CA  . GLU C 1 45  ? -3.65064  22.86729  -3.27190  1.000 24.15522 ? 45  GLU C CA  1 
ATOM   2628 C C   . GLU C 1 45  ? -3.24229  21.45118  -2.87599  1.000 27.87743 ? 45  GLU C C   1 
ATOM   2629 O O   . GLU C 1 45  ? -4.07295  20.53862  -2.84320  1.000 24.22160 ? 45  GLU C O   1 
ATOM   2630 C CB  . GLU C 1 45  ? -4.35709  23.59715  -2.12099  1.000 24.06675 ? 45  GLU C CB  1 
ATOM   2631 C CG  . GLU C 1 45  ? -4.58128  25.08244  -2.46331  1.000 22.46780 ? 45  GLU C CG  1 
ATOM   2632 C CD  . GLU C 1 45  ? -5.36778  25.86824  -1.44058  1.000 25.05315 ? 45  GLU C CD  1 
ATOM   2633 O OE1 . GLU C 1 45  ? -6.60862  25.80407  -1.44213  1.000 32.81300 ? 45  GLU C OE1 1 
ATOM   2634 O OE2 . GLU C 1 45  ? -4.74892  26.59329  -0.64546  1.000 32.22192 ? 45  GLU C OE2 1 
ATOM   2635 N N   . GLN C 1 46  ? -1.95648  21.26585  -2.62043  1.000 27.08774 ? 46  GLN C N   1 
ATOM   2636 C CA  . GLN C 1 46  ? -1.44688  20.03798  -2.03952  1.000 30.01739 ? 46  GLN C CA  1 
ATOM   2637 C C   . GLN C 1 46  ? -0.54037  20.39520  -0.87476  1.000 26.37128 ? 46  GLN C C   1 
ATOM   2638 O O   . GLN C 1 46  ? 0.05063   21.47261  -0.86378  1.000 33.01125 ? 46  GLN C O   1 
ATOM   2639 C CB  . GLN C 1 46  ? -0.68010  19.20353  -3.07551  1.000 25.69389 ? 46  GLN C CB  1 
ATOM   2640 C CG  . GLN C 1 46  ? -1.57329  18.44801  -4.06064  1.000 25.57150 ? 46  GLN C CG  1 
ATOM   2641 C CD  . GLN C 1 46  ? -2.28455  17.25707  -3.42754  1.000 27.35404 ? 46  GLN C CD  1 
ATOM   2642 O OE1 . GLN C 1 46  ? -1.66088  16.44253  -2.73497  1.000 24.78912 ? 46  GLN C OE1 1 
ATOM   2643 N NE2 . GLN C 1 46  ? -3.59246  17.15124  -3.66223  1.000 16.68558 ? 46  GLN C NE2 1 
ATOM   2644 N N   . PRO C 1 47  ? -0.42913  19.52994  0.12453   1.000 23.78077 ? 47  PRO C N   1 
ATOM   2645 C CA  . PRO C 1 47  ? 0.40157   19.86557  1.28230   1.000 27.26087 ? 47  PRO C CA  1 
ATOM   2646 C C   . PRO C 1 47  ? 1.85697   20.03178  0.87047   1.000 31.17205 ? 47  PRO C C   1 
ATOM   2647 O O   . PRO C 1 47  ? 2.36570   19.30241  0.01547   1.000 31.62666 ? 47  PRO C O   1 
ATOM   2648 C CB  . PRO C 1 47  ? 0.21207   18.66335  2.21313   1.000 34.06526 ? 47  PRO C CB  1 
ATOM   2649 C CG  . PRO C 1 47  ? -0.09473  17.52894  1.28700   1.000 32.40122 ? 47  PRO C CG  1 
ATOM   2650 C CD  . PRO C 1 47  ? -0.92196  18.14116  0.18714   1.000 37.62974 ? 47  PRO C CD  1 
ATOM   2651 N N   . ALA C 1 48  ? 2.52869   21.00903  1.47418   1.000 31.87307 ? 48  ALA C N   1 
ATOM   2652 C CA  . ALA C 1 48  ? 3.94981   21.18656  1.19348   1.000 30.51842 ? 48  ALA C CA  1 
ATOM   2653 C C   . ALA C 1 48  ? 4.68273   19.88900  1.46713   1.000 26.03262 ? 48  ALA C C   1 
ATOM   2654 O O   . ALA C 1 48  ? 4.46332   19.24452  2.49416   1.000 28.79068 ? 48  ALA C O   1 
ATOM   2655 C CB  . ALA C 1 48  ? 4.54896   22.31642  2.03118   1.000 26.79806 ? 48  ALA C CB  1 
ATOM   2656 N N   . GLY C 1 49  ? 5.53127   19.49826  0.52762   1.000 25.31171 ? 49  GLY C N   1 
ATOM   2657 C CA  . GLY C 1 49  ? 6.23365   18.23973  0.62696   1.000 32.36193 ? 49  GLY C CA  1 
ATOM   2658 C C   . GLY C 1 49  ? 6.01115   17.36673  -0.58992  1.000 28.52329 ? 49  GLY C C   1 
ATOM   2659 O O   . GLY C 1 49  ? 6.85292   16.52297  -0.91530  1.000 29.16841 ? 49  GLY C O   1 
ATOM   2660 N N   . ASN C 1 50  ? 4.88944   17.58554  -1.27874  1.000 23.65978 ? 50  ASN C N   1 
ATOM   2661 C CA  . ASN C 1 50  ? 4.48300   16.79360  -2.43170  1.000 22.91701 ? 50  ASN C CA  1 
ATOM   2662 C C   . ASN C 1 50  ? 5.19238   17.18582  -3.74501  1.000 28.02249 ? 50  ASN C C   1 
ATOM   2663 O O   . ASN C 1 50  ? 4.82419   16.64895  -4.79239  1.000 29.75879 ? 50  ASN C O   1 
ATOM   2664 C CB  . ASN C 1 50  ? 2.95949   16.89236  -2.61486  1.000 25.70802 ? 50  ASN C CB  1 
ATOM   2665 C CG  . ASN C 1 50  ? 2.17153   16.09084  -1.56482  1.000 29.33081 ? 50  ASN C CG  1 
ATOM   2666 O OD1 . ASN C 1 50  ? 2.64731   15.84981  -0.46021  1.000 24.92601 ? 50  ASN C OD1 1 
ATOM   2667 N ND2 . ASN C 1 50  ? 0.96224   15.66870  -1.92734  1.000 27.23744 ? 50  ASN C ND2 1 
ATOM   2668 N N   . VAL C 1 51  ? 6.19494   18.07012  -3.73698  1.000 29.51638 ? 51  VAL C N   1 
ATOM   2669 C CA  . VAL C 1 51  ? 6.87621   18.50158  -4.95943  1.000 26.59955 ? 51  VAL C CA  1 
ATOM   2670 C C   . VAL C 1 51  ? 8.35223   18.13554  -4.86780  1.000 34.12586 ? 51  VAL C C   1 
ATOM   2671 O O   . VAL C 1 51  ? 9.01414   18.45827  -3.87147  1.000 36.22752 ? 51  VAL C O   1 
ATOM   2672 C CB  . VAL C 1 51  ? 6.71849   20.01283  -5.20738  1.000 21.90477 ? 51  VAL C CB  1 
ATOM   2673 C CG1 . VAL C 1 51  ? 7.65519   20.45105  -6.32398  1.000 24.48959 ? 51  VAL C CG1 1 
ATOM   2674 C CG2 . VAL C 1 51  ? 5.27096   20.35016  -5.53201  1.000 18.07749 ? 51  VAL C CG2 1 
ATOM   2675 N N   . PHE C 1 52  ? 8.87616   17.49072  -5.91922  1.000 32.15081 ? 52  PHE C N   1 
ATOM   2676 C CA  . PHE C 1 52  ? 10.24598  16.96095  -5.92279  1.000 32.29587 ? 52  PHE C CA  1 
ATOM   2677 C C   . PHE C 1 52  ? 11.01735  17.42042  -7.15768  1.000 35.27819 ? 52  PHE C C   1 
ATOM   2678 O O   . PHE C 1 52  ? 10.97202  16.76765  -8.21057  1.000 28.14427 ? 52  PHE C O   1 
ATOM   2679 C CB  . PHE C 1 52  ? 10.24397  15.44625  -5.83700  1.000 32.29409 ? 52  PHE C CB  1 
ATOM   2680 C CG  . PHE C 1 52  ? 10.10483  14.91699  -4.44462  1.000 29.12524 ? 52  PHE C CG  1 
ATOM   2681 C CD1 . PHE C 1 52  ? 8.87999   14.94259  -3.80012  1.000 35.01795 ? 52  PHE C CD1 1 
ATOM   2682 C CD2 . PHE C 1 52  ? 11.18938  14.35689  -3.79657  1.000 27.54643 ? 52  PHE C CD2 1 
ATOM   2683 C CE1 . PHE C 1 52  ? 8.74526   14.43485  -2.52393  1.000 31.11989 ? 52  PHE C CE1 1 
ATOM   2684 C CE2 . PHE C 1 52  ? 11.06371  13.85011  -2.52921  1.000 28.70235 ? 52  PHE C CE2 1 
ATOM   2685 C CZ  . PHE C 1 52  ? 9.83934   13.89512  -1.88880  1.000 33.86127 ? 52  PHE C CZ  1 
ATOM   2686 N N   . LEU C 1 53  ? 11.75728  18.52000  -7.00764  1.000 24.75582 ? 53  LEU C N   1 
ATOM   2687 C CA  . LEU C 1 53  ? 12.66615  18.97346  -8.04963  1.000 23.33550 ? 53  LEU C CA  1 
ATOM   2688 C C   . LEU C 1 53  ? 13.95243  18.15790  -7.97546  1.000 27.44355 ? 53  LEU C C   1 
ATOM   2689 O O   . LEU C 1 53  ? 14.64678  18.17874  -6.95439  1.000 31.78589 ? 53  LEU C O   1 
ATOM   2690 C CB  . LEU C 1 53  ? 12.96585  20.46582  -7.89360  1.000 24.93280 ? 53  LEU C CB  1 
ATOM   2691 C CG  . LEU C 1 53  ? 11.79777  21.43452  -7.69061  1.000 21.60717 ? 53  LEU C CG  1 
ATOM   2692 C CD1 . LEU C 1 53  ? 12.33582  22.85098  -7.51076  1.000 26.15192 ? 53  LEU C CD1 1 
ATOM   2693 C CD2 . LEU C 1 53  ? 10.78657  21.38968  -8.83074  1.000 24.34720 ? 53  LEU C CD2 1 
ATOM   2694 N N   . GLY C 1 54  ? 14.27474  17.45316  -9.05399  1.000 22.86500 ? 54  GLY C N   1 
ATOM   2695 C CA  . GLY C 1 54  ? 15.48688  16.65973  -9.09481  1.000 30.83460 ? 54  GLY C CA  1 
ATOM   2696 C C   . GLY C 1 54  ? 15.54931  15.52861  -8.09186  1.000 31.80459 ? 54  GLY C C   1 
ATOM   2697 O O   . GLY C 1 54  ? 16.63961  15.01712  -7.82092  1.000 25.62441 ? 54  GLY C O   1 
ATOM   2698 N N   . GLY C 1 55  ? 14.40621  15.10504  -7.55133  1.000 29.77280 ? 55  GLY C N   1 
ATOM   2699 C CA  . GLY C 1 55  ? 14.40100  14.17057  -6.44280  1.000 32.61717 ? 55  GLY C CA  1 
ATOM   2700 C C   . GLY C 1 55  ? 14.57294  14.81501  -5.08079  1.000 36.61818 ? 55  GLY C C   1 
ATOM   2701 O O   . GLY C 1 55  ? 14.83611  14.11650  -4.09803  1.000 34.01836 ? 55  GLY C O   1 
ATOM   2702 N N   . VAL C 1 56  ? 14.44502  16.13495  -4.99308  1.000 34.20202 ? 56  VAL C N   1 
ATOM   2703 C CA  . VAL C 1 56  ? 14.56506  16.86635  -3.74003  1.000 33.54115 ? 56  VAL C CA  1 
ATOM   2704 C C   . VAL C 1 56  ? 13.18481  17.37158  -3.36054  1.000 29.76712 ? 56  VAL C C   1 
ATOM   2705 O O   . VAL C 1 56  ? 12.47217  17.92853  -4.20027  1.000 37.23291 ? 56  VAL C O   1 
ATOM   2706 C CB  . VAL C 1 56  ? 15.55840  18.03535  -3.85108  1.000 36.34143 ? 56  VAL C CB  1 
ATOM   2707 C CG1 . VAL C 1 56  ? 15.63845  18.77179  -2.52576  1.000 26.08226 ? 56  VAL C CG1 1 
ATOM   2708 C CG2 . VAL C 1 56  ? 16.93001  17.53162  -4.28848  1.000 36.93724 ? 56  VAL C CG2 1 
ATOM   2709 N N   . GLN C 1 57  ? 12.81762  17.18446  -2.10200  1.000 29.88619 ? 57  GLN C N   1 
ATOM   2710 C CA  . GLN C 1 57  ? 11.51803  17.59334  -1.60137  1.000 32.58720 ? 57  GLN C CA  1 
ATOM   2711 C C   . GLN C 1 57  ? 11.50708  19.09496  -1.35584  1.000 30.23994 ? 57  GLN C C   1 
ATOM   2712 O O   . GLN C 1 57  ? 12.51033  19.68021  -0.94745  1.000 33.00120 ? 57  GLN C O   1 
ATOM   2713 C CB  . GLN C 1 57  ? 11.19558  16.83461  -0.31275  1.000 32.78298 ? 57  GLN C CB  1 
ATOM   2714 C CG  . GLN C 1 57  ? 9.79541   17.06521  0.22576   1.000 32.51571 ? 57  GLN C CG  1 
ATOM   2715 C CD  . GLN C 1 57  ? 9.63792   16.57290  1.64984   1.000 34.14572 ? 57  GLN C CD  1 
ATOM   2716 O OE1 . GLN C 1 57  ? 8.64371   16.86813  2.32252   1.000 35.16204 ? 57  GLN C OE1 1 
ATOM   2717 N NE2 . GLN C 1 57  ? 10.62643  15.82552  2.12225   1.000 31.61483 ? 57  GLN C NE2 1 
ATOM   2718 N N   . GLN C 1 58  ? 10.36729  19.72005  -1.60899  1.000 38.21987 ? 58  GLN C N   1 
ATOM   2719 C CA  . GLN C 1 58  ? 10.27174  21.16926  -1.62384  1.000 35.76586 ? 58  GLN C CA  1 
ATOM   2720 C C   . GLN C 1 58  ? 9.27818   21.63896  -0.58283  1.000 36.62426 ? 58  GLN C C   1 
ATOM   2721 O O   . GLN C 1 58  ? 8.35581   20.91390  -0.19737  1.000 35.30941 ? 58  GLN C O   1 
ATOM   2722 C CB  . GLN C 1 58  ? 9.84117   21.68903  -3.00617  1.000 28.04196 ? 58  GLN C CB  1 
ATOM   2723 C CG  . GLN C 1 58  ? 10.68209  21.13426  -4.12239  1.000 26.91271 ? 58  GLN C CG  1 
ATOM   2724 C CD  . GLN C 1 58  ? 12.08845  21.72534  -4.13417  1.000 29.77455 ? 58  GLN C CD  1 
ATOM   2725 O OE1 . GLN C 1 58  ? 12.25663  22.94502  -4.21384  1.000 24.16706 ? 58  GLN C OE1 1 
ATOM   2726 N NE2 . GLN C 1 58  ? 13.10175  20.86283  -4.04792  1.000 23.26803 ? 58  GLN C NE2 1 
ATOM   2727 N N   . GLY C 1 59  ? 9.48321   22.87688  -0.14553  1.000 38.26156 ? 59  GLY C N   1 
ATOM   2728 C CA  . GLY C 1 59  ? 8.55342   23.55600  0.72617   1.000 35.27675 ? 59  GLY C CA  1 
ATOM   2729 C C   . GLY C 1 59  ? 7.42859   24.14871  -0.08510  1.000 32.36279 ? 59  GLY C C   1 
ATOM   2730 O O   . GLY C 1 59  ? 7.22288   23.81485  -1.25358  1.000 40.75703 ? 59  GLY C O   1 
ATOM   2731 N N   . GLY C 1 60  ? 6.71018   25.07174  0.53514   1.000 34.30602 ? 60  GLY C N   1 
ATOM   2732 C CA  . GLY C 1 60  ? 5.53589   25.61576  -0.11054  1.000 35.57766 ? 60  GLY C CA  1 
ATOM   2733 C C   . GLY C 1 60  ? 5.75644   26.67754  -1.16798  1.000 29.25855 ? 60  GLY C C   1 
ATOM   2734 O O   . GLY C 1 60  ? 4.88862   27.52740  -1.36318  1.000 35.66762 ? 60  GLY C O   1 
ATOM   2735 N N   . ASP C 1 61  ? 6.87941   26.63157  -1.88125  1.000 33.33351 ? 61  ASP C N   1 
ATOM   2736 C CA  . ASP C 1 61  ? 7.33588   27.78306  -2.64628  1.000 40.83271 ? 61  ASP C CA  1 
ATOM   2737 C C   . ASP C 1 61  ? 7.17736   27.66374  -4.15990  1.000 41.15045 ? 61  ASP C C   1 
ATOM   2738 O O   . ASP C 1 61  ? 7.35398   28.67302  -4.84916  1.000 40.52277 ? 61  ASP C O   1 
ATOM   2739 C CB  . ASP C 1 61  ? 8.81245   28.07060  -2.32872  1.000 49.29672 ? 61  ASP C CB  1 
ATOM   2740 C CG  . ASP C 1 61  ? 9.07844   29.54569  -2.01689  1.000 52.77474 ? 61  ASP C CG  1 
ATOM   2741 O OD1 . ASP C 1 61  ? 8.27079   30.41489  -2.42317  1.000 50.34806 ? 61  ASP C OD1 1 
ATOM   2742 O OD2 . ASP C 1 61  ? 10.10522  29.83321  -1.36453  1.000 43.71559 ? 61  ASP C OD2 1 
ATOM   2743 N N   . THR C 1 62  ? 6.86523   26.48430  -4.70348  1.000 39.14692 ? 62  THR C N   1 
ATOM   2744 C CA  . THR C 1 62  ? 6.75809   26.31773  -6.15475  1.000 37.45509 ? 62  THR C CA  1 
ATOM   2745 C C   . THR C 1 62  ? 5.33034   26.54927  -6.64042  1.000 33.07546 ? 62  THR C C   1 
ATOM   2746 O O   . THR C 1 62  ? 4.36789   26.12378  -5.99756  1.000 32.85933 ? 62  THR C O   1 
ATOM   2747 C CB  . THR C 1 62  ? 7.20344   24.91994  -6.58793  1.000 28.82309 ? 62  THR C CB  1 
ATOM   2748 O OG1 . THR C 1 62  ? 8.33971   24.50862  -5.82439  1.000 25.47450 ? 62  THR C OG1 1 
ATOM   2749 C CG2 . THR C 1 62  ? 7.56303   24.92390  -8.08927  1.000 32.13636 ? 62  THR C CG2 1 
ATOM   2750 N N   . ILE C 1 63  ? 5.20318   27.21000  -7.78955  1.000 30.49304 ? 63  ILE C N   1 
ATOM   2751 C CA  . ILE C 1 63  ? 3.92396   27.42304  -8.46671  1.000 27.06278 ? 63  ILE C CA  1 
ATOM   2752 C C   . ILE C 1 63  ? 4.02542   26.81739  -9.85872  1.000 24.31575 ? 63  ILE C C   1 
ATOM   2753 O O   . ILE C 1 63  ? 4.85736   27.25589  -10.66067 1.000 21.96116 ? 63  ILE C O   1 
ATOM   2754 C CB  . ILE C 1 63  ? 3.57142   28.91324  -8.58676  1.000 30.18187 ? 63  ILE C CB  1 
ATOM   2755 C CG1 . ILE C 1 63  ? 3.31096   29.54657  -7.22563  1.000 31.71734 ? 63  ILE C CG1 1 
ATOM   2756 C CG2 . ILE C 1 63  ? 2.38880   29.11824  -9.55510  1.000 23.02715 ? 63  ILE C CG2 1 
ATOM   2757 C CD1 . ILE C 1 63  ? 3.15991   31.05998  -7.31710  1.000 33.34731 ? 63  ILE C CD1 1 
ATOM   2758 N N   . PHE C 1 64  ? 3.17187   25.83339  -10.14990 1.000 25.31541 ? 64  PHE C N   1 
ATOM   2759 C CA  . PHE C 1 64  ? 3.03336   25.25660  -11.48433 1.000 20.88773 ? 64  PHE C CA  1 
ATOM   2760 C C   . PHE C 1 64  ? 1.70224   25.71547  -12.07931 1.000 18.80378 ? 64  PHE C C   1 
ATOM   2761 O O   . PHE C 1 64  ? 0.63142   25.41145  -11.54342 1.000 23.10116 ? 64  PHE C O   1 
ATOM   2762 C CB  . PHE C 1 64  ? 3.12671   23.72736  -11.43733 1.000 19.67584 ? 64  PHE C CB  1 
ATOM   2763 C CG  . PHE C 1 64  ? 3.00482   23.05396  -12.78953 1.000 19.40796 ? 64  PHE C CG  1 
ATOM   2764 C CD1 . PHE C 1 64  ? 2.35630   21.83367  -12.91467 1.000 19.52553 ? 64  PHE C CD1 1 
ATOM   2765 C CD2 . PHE C 1 64  ? 3.51791   23.65677  -13.93987 1.000 26.23338 ? 64  PHE C CD2 1 
ATOM   2766 C CE1 . PHE C 1 64  ? 2.23232   21.20228  -14.16910 1.000 23.71927 ? 64  PHE C CE1 1 
ATOM   2767 C CE2 . PHE C 1 64  ? 3.39989   23.04676  -15.20375 1.000 22.16496 ? 64  PHE C CE2 1 
ATOM   2768 C CZ  . PHE C 1 64  ? 2.75856   21.80933  -15.31982 1.000 23.83660 ? 64  PHE C CZ  1 
ATOM   2769 N N   . VAL C 1 65  ? 1.76972   26.46878  -13.16414 1.000 18.77059 ? 65  VAL C N   1 
ATOM   2770 C CA  . VAL C 1 65  ? 0.59083   26.91064  -13.89171 1.000 16.59364 ? 65  VAL C CA  1 
ATOM   2771 C C   . VAL C 1 65  ? 0.45715   26.03521  -15.12980 1.000 18.09312 ? 65  VAL C C   1 
ATOM   2772 O O   . VAL C 1 65  ? 1.44622   25.78367  -15.82123 1.000 22.69666 ? 65  VAL C O   1 
ATOM   2773 C CB  . VAL C 1 65  ? 0.70879   28.39610  -14.26142 1.000 16.11056 ? 65  VAL C CB  1 
ATOM   2774 C CG1 . VAL C 1 65  ? -0.55814  28.89379  -14.89873 1.000 12.69601 ? 65  VAL C CG1 1 
ATOM   2775 C CG2 . VAL C 1 65  ? 1.07874   29.20104  -13.01796 1.000 13.47824 ? 65  VAL C CG2 1 
ATOM   2776 N N   . HIS C 1 66  ? -0.75235  25.55746  -15.40272 1.000 16.23931 ? 66  HIS C N   1 
ATOM   2777 C CA  . HIS C 1 66  ? -1.01911  24.65531  -16.52682 1.000 19.30203 ? 66  HIS C CA  1 
ATOM   2778 C C   . HIS C 1 66  ? -2.22152  25.23526  -17.27785 1.000 19.77242 ? 66  HIS C C   1 
ATOM   2779 O O   . HIS C 1 66  ? -3.36443  25.12394  -16.83096 1.000 20.08238 ? 66  HIS C O   1 
ATOM   2780 C CB  . HIS C 1 66  ? -1.24938  23.22821  -16.02367 1.000 16.92666 ? 66  HIS C CB  1 
ATOM   2781 C CG  . HIS C 1 66  ? -1.60426  22.23196  -17.08305 1.000 23.89019 ? 66  HIS C CG  1 
ATOM   2782 N ND1 . HIS C 1 66  ? -2.52308  21.22471  -16.86860 1.000 30.45854 ? 66  HIS C ND1 1 
ATOM   2783 C CD2 . HIS C 1 66  ? -1.12598  22.04112  -18.33558 1.000 25.27870 ? 66  HIS C CD2 1 
ATOM   2784 C CE1 . HIS C 1 66  ? -2.62348  20.48229  -17.95662 1.000 30.19519 ? 66  HIS C CE1 1 
ATOM   2785 N NE2 . HIS C 1 66  ? -1.78521  20.95564  -18.86084 1.000 28.69217 ? 66  HIS C NE2 1 
ATOM   2786 N N   . GLY C 1 67  ? -1.95571  25.89493  -18.40128 1.000 12.38634 ? 67  GLY C N   1 
ATOM   2787 C CA  . GLY C 1 67  ? -3.00439  26.51359  -19.17857 1.000 20.58941 ? 67  GLY C CA  1 
ATOM   2788 C C   . GLY C 1 67  ? -3.47970  25.61196  -20.31005 1.000 22.10859 ? 67  GLY C C   1 
ATOM   2789 O O   . GLY C 1 67  ? -2.68672  24.93805  -20.95761 1.000 21.80128 ? 67  GLY C O   1 
ATOM   2790 N N   . LEU C 1 68  ? -4.78736  25.61526  -20.53121 1.000 18.87440 ? 68  LEU C N   1 
ATOM   2791 C CA  . LEU C 1 68  ? -5.41204  24.81466  -21.57855 1.000 26.87778 ? 68  LEU C CA  1 
ATOM   2792 C C   . LEU C 1 68  ? -6.15500  25.75756  -22.51887 1.000 23.15515 ? 68  LEU C C   1 
ATOM   2793 O O   . LEU C 1 68  ? -7.13137  26.40184  -22.11913 1.000 23.69083 ? 68  LEU C O   1 
ATOM   2794 C CB  . LEU C 1 68  ? -6.34281  23.76035  -20.98346 1.000 18.31981 ? 68  LEU C CB  1 
ATOM   2795 C CG  . LEU C 1 68  ? -5.76317  22.62229  -20.12791 1.000 21.41455 ? 68  LEU C CG  1 
ATOM   2796 C CD1 . LEU C 1 68  ? -4.38389  22.12735  -20.57570 1.000 24.43740 ? 68  LEU C CD1 1 
ATOM   2797 C CD2 . LEU C 1 68  ? -5.77245  22.94001  -18.64095 1.000 25.74578 ? 68  LEU C CD2 1 
ATOM   2798 N N   . HIS C 1 69  ? -5.69074  25.82963  -23.76420 1.000 25.24056 ? 69  HIS C N   1 
ATOM   2799 C CA  . HIS C 1 69  ? -6.11759  26.82650  -24.73799 1.000 25.38082 ? 69  HIS C CA  1 
ATOM   2800 C C   . HIS C 1 69  ? -6.70472  26.14977  -25.96047 1.000 23.50754 ? 69  HIS C C   1 
ATOM   2801 O O   . HIS C 1 69  ? -6.38436  24.99855  -26.26108 1.000 19.71426 ? 69  HIS C O   1 
ATOM   2802 C CB  . HIS C 1 69  ? -4.95190  27.69998  -25.21260 1.000 23.91485 ? 69  HIS C CB  1 
ATOM   2803 C CG  . HIS C 1 69  ? -4.27639  28.46645  -24.12885 1.000 24.97551 ? 69  HIS C CG  1 
ATOM   2804 N ND1 . HIS C 1 69  ? -4.83429  28.64484  -22.88220 1.000 26.28837 ? 69  HIS C ND1 1 
ATOM   2805 C CD2 . HIS C 1 69  ? -3.09740  29.13336  -24.11495 1.000 28.41079 ? 69  HIS C CD2 1 
ATOM   2806 C CE1 . HIS C 1 69  ? -4.02444  29.38433  -22.14402 1.000 24.79777 ? 69  HIS C CE1 1 
ATOM   2807 N NE2 . HIS C 1 69  ? -2.95957  29.69017  -22.86510 1.000 22.85270 ? 69  HIS C NE2 1 
ATOM   2808 N N   . ARG C 1 70  ? -7.54648  26.88669  -26.68585 1.000 22.77425 ? 70  ARG C N   1 
ATOM   2809 C CA  . ARG C 1 70  ? -7.86779  26.47105  -28.04887 1.000 19.91126 ? 70  ARG C CA  1 
ATOM   2810 C C   . ARG C 1 70  ? -6.64626  26.67044  -28.94636 1.000 21.85490 ? 70  ARG C C   1 
ATOM   2811 O O   . ARG C 1 70  ? -5.88629  27.63590  -28.79146 1.000 25.66165 ? 70  ARG C O   1 
ATOM   2812 C CB  . ARG C 1 70  ? -9.08597  27.22441  -28.60395 1.000 10.00234 ? 70  ARG C CB  1 
ATOM   2813 C CG  . ARG C 1 70  ? -9.59577  28.37687  -27.77735 1.000 24.08878 ? 70  ARG C CG  1 
ATOM   2814 C CD  . ARG C 1 70  ? -10.89222 28.96487  -28.28801 1.000 27.46614 ? 70  ARG C CD  1 
ATOM   2815 N NE  . ARG C 1 70  ? -11.02201 30.37231  -27.94706 1.000 30.73457 ? 70  ARG C NE  1 
ATOM   2816 C CZ  . ARG C 1 70  ? -12.02685 31.14469  -28.33634 1.000 34.85039 ? 70  ARG C CZ  1 
ATOM   2817 N NH1 . ARG C 1 70  ? -13.03592 30.66476  -29.02264 1.000 35.31944 ? 70  ARG C NH1 1 
ATOM   2818 N NH2 . ARG C 1 70  ? -12.01024 32.43769  -28.03945 1.000 43.63563 ? 70  ARG C NH2 1 
ATOM   2819 N N   . GLU C 1 71  ? -6.43407  25.73594  -29.87237 1.000 18.22664 ? 71  GLU C N   1 
ATOM   2820 C CA  . GLU C 1 71  ? -5.34551  25.90100  -30.82793 1.000 20.11205 ? 71  GLU C CA  1 
ATOM   2821 C C   . GLU C 1 71  ? -5.54826  27.16753  -31.66538 1.000 14.36292 ? 71  GLU C C   1 
ATOM   2822 O O   . GLU C 1 71  ? -6.64105  27.73283  -31.73746 1.000 15.10565 ? 71  GLU C O   1 
ATOM   2823 C CB  . GLU C 1 71  ? -5.24116  24.68876  -31.75784 1.000 15.86333 ? 71  GLU C CB  1 
ATOM   2824 C CG  . GLU C 1 71  ? -4.93008  23.40853  -31.08014 1.000 16.28477 ? 71  GLU C CG  1 
ATOM   2825 C CD  . GLU C 1 71  ? -4.99137  22.22427  -32.03444 1.000 24.77124 ? 71  GLU C CD  1 
ATOM   2826 O OE1 . GLU C 1 71  ? -5.92906  22.15596  -32.85856 1.000 20.20262 ? 71  GLU C OE1 1 
ATOM   2827 O OE2 . GLU C 1 71  ? -4.09125  21.36303  -31.96641 1.000 25.07674 ? 71  GLU C OE2 1 
ATOM   2828 N N   . GLY C 1 72  ? -4.47375  27.60853  -32.31643 1.000 16.90687 ? 72  GLY C N   1 
ATOM   2829 C CA  . GLY C 1 72  ? -4.61044  28.67163  -33.29897 1.000 20.55032 ? 72  GLY C CA  1 
ATOM   2830 C C   . GLY C 1 72  ? -3.75719  29.90849  -33.12246 1.000 18.01553 ? 72  GLY C C   1 
ATOM   2831 O O   . GLY C 1 72  ? -3.58458  30.67991  -34.07043 1.000 21.46888 ? 72  GLY C O   1 
ATOM   2832 N N   . ARG C 1 73  ? -3.21290  30.12007  -31.93208 1.000 17.29676 ? 73  ARG C N   1 
ATOM   2833 C CA  . ARG C 1 73  ? -2.42891  31.31658  -31.69043 1.000 12.80039 ? 73  ARG C CA  1 
ATOM   2834 C C   . ARG C 1 73  ? -0.98707  31.08837  -32.09933 1.000 15.57396 ? 73  ARG C C   1 
ATOM   2835 O O   . ARG C 1 73  ? -0.52232  29.94996  -32.20169 1.000 21.17319 ? 73  ARG C O   1 
ATOM   2836 C CB  . ARG C 1 73  ? -2.53006  31.74358  -30.22219 1.000 14.50031 ? 73  ARG C CB  1 
ATOM   2837 C CG  . ARG C 1 73  ? -3.96907  32.02583  -29.86285 1.000 20.94310 ? 73  ARG C CG  1 
ATOM   2838 C CD  . ARG C 1 73  ? -4.18978  33.25519  -28.99024 1.000 22.67858 ? 73  ARG C CD  1 
ATOM   2839 N NE  . ARG C 1 73  ? -5.57814  33.29815  -28.55731 1.000 19.22544 ? 73  ARG C NE  1 
ATOM   2840 C CZ  . ARG C 1 73  ? -6.15141  32.36051  -27.81021 1.000 29.08967 ? 73  ARG C CZ  1 
ATOM   2841 N NH1 . ARG C 1 73  ? -5.45312  31.35580  -27.29281 1.000 28.33712 ? 73  ARG C NH1 1 
ATOM   2842 N NH2 . ARG C 1 73  ? -7.45963  32.41468  -27.59369 1.000 25.36188 ? 73  ARG C NH2 1 
ATOM   2843 N N   . SER C 1 74  ? -0.27051  32.19001  -32.33257 1.000 13.49653 ? 74  SER C N   1 
ATOM   2844 C CA  . SER C 1 74  ? 1.12211   32.05786  -32.74058 1.000 15.89917 ? 74  SER C CA  1 
ATOM   2845 C C   . SER C 1 74  ? 1.99772   31.69306  -31.54200 1.000 14.21905 ? 74  SER C C   1 
ATOM   2846 O O   . SER C 1 74  ? 1.60961   31.86429  -30.38969 1.000 17.25673 ? 74  SER C O   1 
ATOM   2847 C CB  . SER C 1 74  ? 1.62750   33.34919  -33.38858 1.000 15.25630 ? 74  SER C CB  1 
ATOM   2848 O OG  . SER C 1 74  ? 1.83894   34.38230  -32.42098 1.000 14.14983 ? 74  SER C OG  1 
ATOM   2849 N N   . ALA C 1 75  ? 3.19614   31.18521  -31.83725 1.000 15.27019 ? 75  ALA C N   1 
ATOM   2850 C CA  . ALA C 1 75  ? 4.19250   30.95415  -30.80068 1.000 15.15010 ? 75  ALA C CA  1 
ATOM   2851 C C   . ALA C 1 75  ? 4.67322   32.26603  -30.19783 1.000 14.42749 ? 75  ALA C C   1 
ATOM   2852 O O   . ALA C 1 75  ? 4.94694   32.35213  -28.99858 1.000 18.79467 ? 75  ALA C O   1 
ATOM   2853 C CB  . ALA C 1 75  ? 5.37684   30.18584  -31.37707 1.000 17.92034 ? 75  ALA C CB  1 
ATOM   2854 N N   . ASP C 1 76  ? 4.83079   33.28040  -31.02888 1.000 19.57906 ? 76  ASP C N   1 
ATOM   2855 C CA  . ASP C 1 76  ? 5.23978   34.59172  -30.55542 1.000 16.73761 ? 76  ASP C CA  1 
ATOM   2856 C C   . ASP C 1 76  ? 4.27528   35.09045  -29.49513 1.000 16.53262 ? 76  ASP C C   1 
ATOM   2857 O O   . ASP C 1 76  ? 4.67647   35.40117  -28.36813 1.000 14.25237 ? 76  ASP C O   1 
ATOM   2858 C CB  . ASP C 1 76  ? 5.31142   35.50978  -31.76963 1.000 20.01664 ? 76  ASP C CB  1 
ATOM   2859 C CG  . ASP C 1 76  ? 5.64017   34.71586  -33.04462 1.000 32.02369 ? 76  ASP C CG  1 
ATOM   2860 O OD1 . ASP C 1 76  ? 6.79962   34.23106  -33.20673 1.000 28.64185 ? 76  ASP C OD1 1 
ATOM   2861 O OD2 . ASP C 1 76  ? 4.70707   34.49009  -33.83994 1.000 34.14836 ? 76  ASP C OD2 1 
ATOM   2862 N N   . LEU C 1 77  ? 2.98060   35.08478  -29.82110 1.000 17.63854 ? 77  LEU C N   1 
ATOM   2863 C CA  . LEU C 1 77  ? 1.96105   35.46283  -28.85434 1.000 15.39558 ? 77  LEU C CA  1 
ATOM   2864 C C   . LEU C 1 77  ? 2.01905   34.58180  -27.61634 1.000 13.96778 ? 77  LEU C C   1 
ATOM   2865 O O   . LEU C 1 77  ? 1.88783   35.06537  -26.49554 1.000 11.73604 ? 77  LEU C O   1 
ATOM   2866 C CB  . LEU C 1 77  ? 0.57451   35.38234  -29.49148 1.000 16.41443 ? 77  LEU C CB  1 
ATOM   2867 C CG  . LEU C 1 77  ? -0.69250  35.58551  -28.62834 1.000 24.11307 ? 77  LEU C CG  1 
ATOM   2868 C CD1 . LEU C 1 77  ? -1.13710  34.32810  -27.83093 1.000 22.42188 ? 77  LEU C CD1 1 
ATOM   2869 C CD2 . LEU C 1 77  ? -0.54378  36.75168  -27.70963 1.000 18.74067 ? 77  LEU C CD2 1 
ATOM   2870 N N   . LYS C 1 78  ? 2.14662   33.27581  -27.80305 1.000 19.12819 ? 78  LYS C N   1 
ATOM   2871 C CA  . LYS C 1 78  ? 2.14220   32.39574  -26.64980 1.000 15.76357 ? 78  LYS C CA  1 
ATOM   2872 C C   . LYS C 1 78  ? 3.38108   32.61522  -25.78338 1.000 15.76166 ? 78  LYS C C   1 
ATOM   2873 O O   . LYS C 1 78  ? 3.29744   32.57561  -24.55305 1.000 13.88382 ? 78  LYS C O   1 
ATOM   2874 C CB  . LYS C 1 78  ? 1.99311   30.95546  -27.12437 1.000 14.07085 ? 78  LYS C CB  1 
ATOM   2875 C CG  . LYS C 1 78  ? 0.53757   30.51705  -27.23254 1.000 9.11861  ? 78  LYS C CG  1 
ATOM   2876 C CD  . LYS C 1 78  ? 0.44023   29.10889  -27.81608 1.000 15.27580 ? 78  LYS C CD  1 
ATOM   2877 C CE  . LYS C 1 78  ? 1.16511   29.04180  -29.17880 1.000 14.39070 ? 78  LYS C CE  1 
ATOM   2878 N NZ  . LYS C 1 78  ? 1.35193   27.68713  -29.73588 1.000 10.97029 ? 78  LYS C NZ  1 
ATOM   2879 N N   . GLY C 1 79  ? 4.52579   32.89766  -26.39948 1.000 18.44730 ? 79  GLY C N   1 
ATOM   2880 C CA  . GLY C 1 79  ? 5.70165   33.23450  -25.61713 1.000 17.42446 ? 79  GLY C CA  1 
ATOM   2881 C C   . GLY C 1 79  ? 5.54059   34.51681  -24.82541 1.000 14.55710 ? 79  GLY C C   1 
ATOM   2882 O O   . GLY C 1 79  ? 6.11135   34.64713  -23.74057 1.000 19.48343 ? 79  GLY C O   1 
ATOM   2883 N N   . GLN C 1 80  ? 4.79112   35.48434  -25.36406 1.000 13.76888 ? 80  GLN C N   1 
ATOM   2884 C CA  . GLN C 1 80  ? 4.45421   36.68892  -24.61000 1.000 16.47124 ? 80  GLN C CA  1 
ATOM   2885 C C   . GLN C 1 80  ? 3.55095   36.33836  -23.45120 1.000 19.88488 ? 80  GLN C C   1 
ATOM   2886 O O   . GLN C 1 80  ? 3.77919   36.77586  -22.31566 1.000 19.95409 ? 80  GLN C O   1 
ATOM   2887 C CB  . GLN C 1 80  ? 3.75345   37.73404  -25.49108 1.000 13.60698 ? 80  GLN C CB  1 
ATOM   2888 C CG  . GLN C 1 80  ? 4.64195   38.86160  -26.00975 1.000 22.73273 ? 80  GLN C CG  1 
ATOM   2889 C CD  . GLN C 1 80  ? 3.91847   40.23392  -26.07513 1.000 38.42379 ? 80  GLN C CD  1 
ATOM   2890 O OE1 . GLN C 1 80  ? 3.02542   40.45318  -26.91251 1.000 32.40183 ? 80  GLN C OE1 1 
ATOM   2891 N NE2 . GLN C 1 80  ? 4.31274   41.15701  -25.18345 1.000 26.78273 ? 80  GLN C NE2 1 
ATOM   2892 N N   . LEU C 1 81  ? 2.51260   35.54392  -23.72607 1.000 15.13725 ? 81  LEU C N   1 
ATOM   2893 C CA  . LEU C 1 81  ? 1.57272   35.20341  -22.67838 1.000 15.30832 ? 81  LEU C CA  1 
ATOM   2894 C C   . LEU C 1 81  ? 2.28975   34.48811  -21.54819 1.000 18.04501 ? 81  LEU C C   1 
ATOM   2895 O O   . LEU C 1 81  ? 2.11495   34.82037  -20.37265 1.000 18.82932 ? 81  LEU C O   1 
ATOM   2896 C CB  . LEU C 1 81  ? 0.43448   34.35889  -23.24839 1.000 17.67333 ? 81  LEU C CB  1 
ATOM   2897 C CG  . LEU C 1 81  ? -0.76389  34.24656  -22.30221 1.000 15.94100 ? 81  LEU C CG  1 
ATOM   2898 C CD1 . LEU C 1 81  ? -1.01247  35.58152  -21.64044 1.000 19.56898 ? 81  LEU C CD1 1 
ATOM   2899 C CD2 . LEU C 1 81  ? -2.03228  33.73456  -23.02451 1.000 16.19912 ? 81  LEU C CD2 1 
ATOM   2900 N N   . ALA C 1 82  ? 3.13408   33.52573  -21.89528 1.000 19.12044 ? 82  ALA C N   1 
ATOM   2901 C CA  . ALA C 1 82  ? 3.86402   32.77602  -20.89083 1.000 19.81128 ? 82  ALA C CA  1 
ATOM   2902 C C   . ALA C 1 82  ? 4.87828   33.63902  -20.15175 1.000 20.20321 ? 82  ALA C C   1 
ATOM   2903 O O   . ALA C 1 82  ? 5.21221   33.32232  -19.01235 1.000 21.94791 ? 82  ALA C O   1 
ATOM   2904 C CB  . ALA C 1 82  ? 4.54117   31.56791  -21.53170 1.000 18.32925 ? 82  ALA C CB  1 
ATOM   2905 N N   . GLN C 1 83  ? 5.33761   34.74575  -20.74522 1.000 25.30034 ? 83  GLN C N   1 
ATOM   2906 C CA  . GLN C 1 83  ? 6.28157   35.60721  -20.03544 1.000 24.56691 ? 83  GLN C CA  1 
ATOM   2907 C C   . GLN C 1 83  ? 5.57538   36.62084  -19.15274 1.000 20.06902 ? 83  GLN C C   1 
ATOM   2908 O O   . GLN C 1 83  ? 6.10700   37.01299  -18.10928 1.000 21.19064 ? 83  GLN C O   1 
ATOM   2909 C CB  . GLN C 1 83  ? 7.19568   36.33342  -21.01157 1.000 20.02463 ? 83  GLN C CB  1 
ATOM   2910 C CG  . GLN C 1 83  ? 8.19490   37.23487  -20.31639 1.000 29.92411 ? 83  GLN C CG  1 
ATOM   2911 C CD  . GLN C 1 83  ? 9.37488   36.45790  -19.74455 1.000 32.69882 ? 83  GLN C CD  1 
ATOM   2912 O OE1 . GLN C 1 83  ? 10.11619  35.82006  -20.48790 1.000 29.25268 ? 83  GLN C OE1 1 
ATOM   2913 N NE2 . GLN C 1 83  ? 9.54471   36.50197  -18.42420 1.000 26.85628 ? 83  GLN C NE2 1 
ATOM   2914 N N   . ARG C 1 84  ? 4.37919   37.03158  -19.53989 1.000 21.23895 ? 84  ARG C N   1 
ATOM   2915 C CA  . ARG C 1 84  ? 3.59057   37.90990  -18.68617 1.000 22.72673 ? 84  ARG C CA  1 
ATOM   2916 C C   . ARG C 1 84  ? 3.08605   37.16865  -17.45915 1.000 22.65898 ? 84  ARG C C   1 
ATOM   2917 O O   . ARG C 1 84  ? 3.07669   37.71916  -16.34973 1.000 22.04227 ? 84  ARG C O   1 
ATOM   2918 C CB  . ARG C 1 84  ? 2.40682   38.48764  -19.46306 1.000 21.27008 ? 84  ARG C CB  1 
ATOM   2919 C CG  . ARG C 1 84  ? 1.77693   39.70211  -18.78979 1.000 32.07161 ? 84  ARG C CG  1 
ATOM   2920 C CD  . ARG C 1 84  ? 2.82309   40.78737  -18.59884 1.000 31.13213 ? 84  ARG C CD  1 
ATOM   2921 N NE  . ARG C 1 84  ? 2.51468   41.73004  -17.53177 1.000 43.61772 ? 84  ARG C NE  1 
ATOM   2922 C CZ  . ARG C 1 84  ? 3.37541   42.62965  -17.06857 1.000 46.86296 ? 84  ARG C CZ  1 
ATOM   2923 N NH1 . ARG C 1 84  ? 4.59761   42.73365  -17.56401 1.000 43.62821 ? 84  ARG C NH1 1 
ATOM   2924 N NH2 . ARG C 1 84  ? 3.00462   43.43984  -16.08020 1.000 34.70519 ? 84  ARG C NH2 1 
ATOM   2925 N N   . ILE C 1 85  ? 2.61663   35.93405  -17.64910 1.000 19.90822 ? 85  ILE C N   1 
ATOM   2926 C CA  . ILE C 1 85  ? 2.05147   35.19400  -16.53966 1.000 19.44044 ? 85  ILE C CA  1 
ATOM   2927 C C   . ILE C 1 85  ? 3.10680   34.98969  -15.46869 1.000 22.25048 ? 85  ILE C C   1 
ATOM   2928 O O   . ILE C 1 85  ? 2.82030   35.05777  -14.27135 1.000 22.13522 ? 85  ILE C O   1 
ATOM   2929 C CB  . ILE C 1 85  ? 1.46216   33.86546  -17.02816 1.000 23.80191 ? 85  ILE C CB  1 
ATOM   2930 C CG1 . ILE C 1 85  ? 0.11837   34.13219  -17.68792 1.000 19.48200 ? 85  ILE C CG1 1 
ATOM   2931 C CG2 . ILE C 1 85  ? 1.32747   32.85112  -15.85093 1.000 20.49781 ? 85  ILE C CG2 1 
ATOM   2932 C CD1 . ILE C 1 85  ? -0.36272  33.00591  -18.58457 1.000 12.42546 ? 85  ILE C CD1 1 
ATOM   2933 N N   . VAL C 1 86  ? 4.34957   34.78629  -15.88719 1.000 20.85012 ? 86  VAL C N   1 
ATOM   2934 C CA  . VAL C 1 86  ? 5.43695   34.63046  -14.93537 1.000 24.15536 ? 86  VAL C CA  1 
ATOM   2935 C C   . VAL C 1 86  ? 5.59579   35.89703  -14.10443 1.000 24.35617 ? 86  VAL C C   1 
ATOM   2936 O O   . VAL C 1 86  ? 5.57720   35.85646  -12.86768 1.000 29.97308 ? 86  VAL C O   1 
ATOM   2937 C CB  . VAL C 1 86  ? 6.72875   34.25883  -15.68201 1.000 20.23914 ? 86  VAL C CB  1 
ATOM   2938 C CG1 . VAL C 1 86  ? 7.93352   34.38325  -14.78741 1.000 21.42676 ? 86  VAL C CG1 1 
ATOM   2939 C CG2 . VAL C 1 86  ? 6.61829   32.86534  -16.20981 1.000 18.45583 ? 86  VAL C CG2 1 
ATOM   2940 N N   . ASP C 1 87  ? 5.73205   37.04058  -14.77082 1.000 23.61694 ? 87  ASP C N   1 
ATOM   2941 C CA  . ASP C 1 87  ? 5.99690   38.28920  -14.05884 1.000 30.58150 ? 87  ASP C CA  1 
ATOM   2942 C C   . ASP C 1 87  ? 4.80874   38.71544  -13.19171 1.000 27.44531 ? 87  ASP C C   1 
ATOM   2943 O O   . ASP C 1 87  ? 5.00037   39.22564  -12.08058 1.000 26.66052 ? 87  ASP C O   1 
ATOM   2944 C CB  . ASP C 1 87  ? 6.36724   39.39564  -15.05981 1.000 24.30708 ? 87  ASP C CB  1 
ATOM   2945 C CG  . ASP C 1 87  ? 7.58035   39.03837  -15.92455 1.000 29.49033 ? 87  ASP C CG  1 
ATOM   2946 O OD1 . ASP C 1 87  ? 8.54357   38.40681  -15.42504 1.000 29.30522 ? 87  ASP C OD1 1 
ATOM   2947 O OD2 . ASP C 1 87  ? 7.57044   39.40368  -17.12256 1.000 38.22988 ? 87  ASP C OD2 1 
ATOM   2948 N N   . ASP C 1 88  ? 3.57838   38.51322  -13.67315 1.000 25.68792 ? 88  ASP C N   1 
ATOM   2949 C CA  . ASP C 1 88  ? 2.40145   38.99790  -12.95323 1.000 21.45572 ? 88  ASP C CA  1 
ATOM   2950 C C   . ASP C 1 88  ? 1.97267   38.06392  -11.82989 1.000 29.04054 ? 88  ASP C C   1 
ATOM   2951 O O   . ASP C 1 88  ? 1.31494   38.51510  -10.88177 1.000 34.57549 ? 88  ASP C O   1 
ATOM   2952 C CB  . ASP C 1 88  ? 1.21060   39.18941  -13.89605 1.000 27.21093 ? 88  ASP C CB  1 
ATOM   2953 C CG  . ASP C 1 88  ? 1.43421   40.28699  -14.93101 1.000 30.49573 ? 88  ASP C CG  1 
ATOM   2954 O OD1 . ASP C 1 88  ? 2.32113   41.14245  -14.72801 1.000 24.61067 ? 88  ASP C OD1 1 
ATOM   2955 O OD2 . ASP C 1 88  ? 0.69879   40.29386  -15.94418 1.000 27.98974 ? 88  ASP C OD2 1 
ATOM   2956 N N   . VAL C 1 89  ? 2.28980   36.76826  -11.91800 1.000 26.97547 ? 89  VAL C N   1 
ATOM   2957 C CA  . VAL C 1 89  ? 2.04790   35.90221  -10.76611 1.000 26.36998 ? 89  VAL C CA  1 
ATOM   2958 C C   . VAL C 1 89  ? 3.16900   36.03823  -9.75142  1.000 27.83413 ? 89  VAL C C   1 
ATOM   2959 O O   . VAL C 1 89  ? 2.95377   35.77092  -8.56215  1.000 33.27167 ? 89  VAL C O   1 
ATOM   2960 C CB  . VAL C 1 89  ? 1.87893   34.42211  -11.14388 1.000 21.90281 ? 89  VAL C CB  1 
ATOM   2961 C CG1 . VAL C 1 89  ? 0.79530   34.24600  -12.20852 1.000 24.27151 ? 89  VAL C CG1 1 
ATOM   2962 C CG2 . VAL C 1 89  ? 3.20462   33.83452  -11.58997 1.000 29.10013 ? 89  VAL C CG2 1 
ATOM   2963 N N   . SER C 1 90  ? 4.35789   36.45378  -10.19370 1.000 23.91400 ? 90  SER C N   1 
ATOM   2964 C CA  . SER C 1 90  ? 5.41236   36.82220  -9.25619  1.000 29.03773 ? 90  SER C CA  1 
ATOM   2965 C C   . SER C 1 90  ? 5.00100   38.01676  -8.39592  1.000 33.95153 ? 90  SER C C   1 
ATOM   2966 O O   . SER C 1 90  ? 5.31166   38.06832  -7.20097  1.000 29.93543 ? 90  SER C O   1 
ATOM   2967 C CB  . SER C 1 90  ? 6.69363   37.12086  -10.02235 1.000 27.39932 ? 90  SER C CB  1 
ATOM   2968 O OG  . SER C 1 90  ? 7.65082   37.72963  -9.19027  1.000 30.49149 ? 90  SER C OG  1 
ATOM   2969 N N   . VAL C 1 91  ? 4.28638   38.98173  -8.97475  1.000 36.29461 ? 91  VAL C N   1 
ATOM   2970 C CA  . VAL C 1 91  ? 3.84612   40.13446  -8.19187  1.000 31.41266 ? 91  VAL C CA  1 
ATOM   2971 C C   . VAL C 1 91  ? 2.68560   39.76005  -7.28462  1.000 35.02353 ? 91  VAL C C   1 
ATOM   2972 O O   . VAL C 1 91  ? 2.76689   39.89535  -6.05892  1.000 40.76618 ? 91  VAL C O   1 
ATOM   2973 C CB  . VAL C 1 91  ? 3.46307   41.31033  -9.10342  1.000 28.72255 ? 91  VAL C CB  1 
ATOM   2974 C CG1 . VAL C 1 91  ? 2.53618   42.27019  -8.34334  1.000 37.50455 ? 91  VAL C CG1 1 
ATOM   2975 C CG2 . VAL C 1 91  ? 4.69784   42.03519  -9.55239  1.000 30.08200 ? 91  VAL C CG2 1 
ATOM   2976 N N   . ALA C 1 92  ? 1.58546   39.29420  -7.88089  1.000 31.96301 ? 92  ALA C N   1 
ATOM   2977 C CA  . ALA C 1 92  ? 0.34115   39.11720  -7.14265  1.000 29.79227 ? 92  ALA C CA  1 
ATOM   2978 C C   . ALA C 1 92  ? 0.50735   38.19272  -5.94190  1.000 33.05491 ? 92  ALA C C   1 
ATOM   2979 O O   . ALA C 1 92  ? -0.21740  38.32611  -4.95057  1.000 38.24991 ? 92  ALA C O   1 
ATOM   2980 C CB  . ALA C 1 92  ? -0.73348  38.58001  -8.08073  1.000 27.28693 ? 92  ALA C CB  1 
ATOM   2981 N N   . ALA C 1 93  ? 1.44377   37.25226  -6.01178  1.000 29.62345 ? 93  ALA C N   1 
ATOM   2982 C CA  . ALA C 1 93  ? 1.65637   36.28227  -4.95255  1.000 29.51406 ? 93  ALA C CA  1 
ATOM   2983 C C   . ALA C 1 93  ? 2.99716   36.46874  -4.26023  1.000 34.36386 ? 93  ALA C C   1 
ATOM   2984 O O   . ALA C 1 93  ? 3.44218   35.56596  -3.54623  1.000 30.93188 ? 93  ALA C O   1 
ATOM   2985 C CB  . ALA C 1 93  ? 1.55012   34.86620  -5.51292  1.000 40.96724 ? 93  ALA C CB  1 
ATOM   2986 N N   . GLU C 1 94  ? 3.66069   37.60434  -4.47905  1.000 32.72439 ? 94  GLU C N   1 
ATOM   2987 C CA  . GLU C 1 94  ? 4.90538   37.96254  -3.80411  1.000 39.91441 ? 94  GLU C CA  1 
ATOM   2988 C C   . GLU C 1 94  ? 6.01437   36.92763  -4.00339  1.000 34.92937 ? 94  GLU C C   1 
ATOM   2989 O O   . GLU C 1 94  ? 6.93820   36.83197  -3.18930  1.000 35.59644 ? 94  GLU C O   1 
ATOM   2990 C CB  . GLU C 1 94  ? 4.66601   38.18916  -2.30951  1.000 44.04215 ? 94  GLU C CB  1 
ATOM   2991 C CG  . GLU C 1 94  ? 3.53871   39.13861  -2.00724  1.000 38.64940 ? 94  GLU C CG  1 
ATOM   2992 C CD  . GLU C 1 94  ? 3.64144   39.69576  -0.61149  1.000 50.17603 ? 94  GLU C CD  1 
ATOM   2993 O OE1 . GLU C 1 94  ? 4.78572   39.87915  -0.13944  1.000 44.53866 ? 94  GLU C OE1 1 
ATOM   2994 O OE2 . GLU C 1 94  ? 2.58674   39.94691  0.01247   1.000 57.69263 ? 94  GLU C OE2 1 
ATOM   2995 N N   . ILE C 1 95  ? 5.96173   36.16158  -5.08257  1.000 34.10252 ? 95  ILE C N   1 
ATOM   2996 C CA  . ILE C 1 95  ? 6.91404   35.09382  -5.32116  1.000 34.84364 ? 95  ILE C CA  1 
ATOM   2997 C C   . ILE C 1 95  ? 8.00965   35.62845  -6.23915  1.000 33.09238 ? 95  ILE C C   1 
ATOM   2998 O O   . ILE C 1 95  ? 7.91692   36.73010  -6.77284  1.000 36.86488 ? 95  ILE C O   1 
ATOM   2999 C CB  . ILE C 1 95  ? 6.19262   33.82326  -5.86842  1.000 27.73169 ? 95  ILE C CB  1 
ATOM   3000 C CG1 . ILE C 1 95  ? 5.52508   33.07454  -4.72588  1.000 29.56223 ? 95  ILE C CG1 1 
ATOM   3001 C CG2 . ILE C 1 95  ? 7.10365   32.86706  -6.57861  1.000 37.36938 ? 95  ILE C CG2 1 
ATOM   3002 C CD1 . ILE C 1 95  ? 5.76490   31.55410  -4.75367  1.000 31.80177 ? 95  ILE C CD1 1 
ATOM   3003 N N   . ASP C 1 96  ? 9.11225   34.89258  -6.34262  1.000 39.15211 ? 96  ASP C N   1 
ATOM   3004 C CA  . ASP C 1 96  ? 10.15977  35.16489  -7.31690  1.000 39.10913 ? 96  ASP C CA  1 
ATOM   3005 C C   . ASP C 1 96  ? 10.06773  34.20695  -8.50453  1.000 38.04257 ? 96  ASP C C   1 
ATOM   3006 O O   . ASP C 1 96  ? 9.48239   33.12452  -8.42423  1.000 33.39534 ? 96  ASP C O   1 
ATOM   3007 C CB  . ASP C 1 96  ? 11.54116  35.06532  -6.67206  1.000 32.67580 ? 96  ASP C CB  1 
ATOM   3008 C CG  . ASP C 1 96  ? 11.73854  33.76648  -5.93066  1.000 45.13194 ? 96  ASP C CG  1 
ATOM   3009 O OD1 . ASP C 1 96  ? 11.03488  33.53799  -4.91710  1.000 46.94979 ? 96  ASP C OD1 1 
ATOM   3010 O OD2 . ASP C 1 96  ? 12.59378  32.96498  -6.36656  1.000 47.42713 ? 96  ASP C OD2 1 
ATOM   3011 N N   . ARG C 1 97  ? 10.70959  34.61584  -9.60409  1.000 43.18687 ? 97  ARG C N   1 
ATOM   3012 C CA  . ARG C 1 97  ? 10.50148  33.98499  -10.90517 1.000 35.45584 ? 97  ARG C CA  1 
ATOM   3013 C C   . ARG C 1 97  ? 10.99224  32.53508  -10.94097 1.000 40.04027 ? 97  ARG C C   1 
ATOM   3014 O O   . ARG C 1 97  ? 10.26942  31.63830  -11.38643 1.000 34.75647 ? 97  ARG C O   1 
ATOM   3015 C CB  . ARG C 1 97  ? 11.20091  34.80878  -11.98551 1.000 36.44071 ? 97  ARG C CB  1 
ATOM   3016 C CG  . ARG C 1 97  ? 10.55395  36.14106  -12.28193 1.000 42.09388 ? 97  ARG C CG  1 
ATOM   3017 C CD  . ARG C 1 97  ? 11.60318  37.23468  -12.41562 1.000 52.14536 ? 97  ARG C CD  1 
ATOM   3018 N NE  . ARG C 1 97  ? 11.89991  37.83906  -11.12182 1.000 51.42834 ? 97  ARG C NE  1 
ATOM   3019 C CZ  . ARG C 1 97  ? 11.19695  38.83393  -10.60221 1.000 40.89972 ? 97  ARG C CZ  1 
ATOM   3020 N NH1 . ARG C 1 97  ? 10.17093  39.36284  -11.24825 1.000 43.88415 ? 97  ARG C NH1 1 
ATOM   3021 N NH2 . ARG C 1 97  ? 11.52410  39.30331  -9.40575  1.000 46.66354 ? 97  ARG C NH2 1 
ATOM   3022 N N   . LYS C 1 98  ? 12.23187  32.28390  -10.51652 1.000 37.47075 ? 98  LYS C N   1 
ATOM   3023 C CA  . LYS C 1 98  ? 12.80488  30.95388  -10.71677 1.000 34.02428 ? 98  LYS C CA  1 
ATOM   3024 C C   . LYS C 1 98  ? 12.09543  29.87121  -9.90028  1.000 35.86244 ? 98  LYS C C   1 
ATOM   3025 O O   . LYS C 1 98  ? 12.51625  28.70363  -9.93749  1.000 31.34317 ? 98  LYS C O   1 
ATOM   3026 C CB  . LYS C 1 98  ? 14.30249  30.97918  -10.40399 1.000 37.93454 ? 98  LYS C CB  1 
ATOM   3027 C CG  . LYS C 1 98  ? 15.02979  32.24590  -10.90394 1.000 42.32357 ? 98  LYS C CG  1 
ATOM   3028 C CD  . LYS C 1 98  ? 14.93063  32.40998  -12.40811 1.000 38.82022 ? 98  LYS C CD  1 
ATOM   3029 C CE  . LYS C 1 98  ? 14.54929  33.81780  -12.82040 1.000 43.29231 ? 98  LYS C CE  1 
ATOM   3030 N NZ  . LYS C 1 98  ? 14.13584  33.88216  -14.26418 1.000 37.77574 ? 98  LYS C NZ  1 
ATOM   3031 N N   . HIS C 1 99  ? 11.04836  30.23801  -9.16006  1.000 30.93460 ? 99  HIS C N   1 
ATOM   3032 C CA  . HIS C 1 99  ? 10.11388  29.29768  -8.56725  1.000 34.25117 ? 99  HIS C CA  1 
ATOM   3033 C C   . HIS C 1 99  ? 8.86906   29.06418  -9.41230  1.000 31.61964 ? 99  HIS C C   1 
ATOM   3034 O O   . HIS C 1 99  ? 8.01480   28.27010  -9.00427  1.000 26.94274 ? 99  HIS C O   1 
ATOM   3035 C CB  . HIS C 1 99  ? 9.66044   29.78527  -7.19271  1.000 41.98985 ? 99  HIS C CB  1 
ATOM   3036 C CG  . HIS C 1 99  ? 10.75060  29.84080  -6.17194  1.000 48.33566 ? 99  HIS C CG  1 
ATOM   3037 N ND1 . HIS C 1 99  ? 10.50953  30.13161  -4.84669  1.000 39.63827 ? 99  HIS C ND1 1 
ATOM   3038 C CD2 . HIS C 1 99  ? 12.08548  29.65150  -6.28172  1.000 43.77268 ? 99  HIS C CD2 1 
ATOM   3039 C CE1 . HIS C 1 99  ? 11.65230  30.11487  -4.18437  1.000 52.45462 ? 99  HIS C CE1 1 
ATOM   3040 N NE2 . HIS C 1 99  ? 12.62301  29.82630  -5.03164  1.000 43.89494 ? 99  HIS C NE2 1 
ATOM   3041 N N   . ILE C 1 100 ? 8.72119   29.74768  -10.55095 1.000 27.32018 ? 100 ILE C N   1 
ATOM   3042 C CA  . ILE C 1 100 ? 7.47766   29.74285  -11.31887 1.000 25.37206 ? 100 ILE C CA  1 
ATOM   3043 C C   . ILE C 1 100 ? 7.65428   28.91104  -12.57925 1.000 22.88685 ? 100 ILE C C   1 
ATOM   3044 O O   . ILE C 1 100 ? 8.61657   29.09254  -13.33298 1.000 24.47621 ? 100 ILE C O   1 
ATOM   3045 C CB  . ILE C 1 100 ? 7.00358   31.16170  -11.66736 1.000 27.38756 ? 100 ILE C CB  1 
ATOM   3046 C CG1 . ILE C 1 100 ? 6.52042   31.87135  -10.40429 1.000 26.73034 ? 100 ILE C CG1 1 
ATOM   3047 C CG2 . ILE C 1 100 ? 5.89141   31.09648  -12.72004 1.000 19.75372 ? 100 ILE C CG2 1 
ATOM   3048 C CD1 . ILE C 1 100 ? 6.58921   33.36076  -10.47890 1.000 24.64365 ? 100 ILE C CD1 1 
ATOM   3049 N N   . TRP C 1 101 ? 6.70498   28.01521  -12.80864 1.000 22.93879 ? 101 TRP C N   1 
ATOM   3050 C CA  . TRP C 1 101 ? 6.66416   27.12330  -13.94745 1.000 16.10803 ? 101 TRP C CA  1 
ATOM   3051 C C   . TRP C 1 101 ? 5.34042   27.30481  -14.66904 1.000 24.08915 ? 101 TRP C C   1 
ATOM   3052 O O   . TRP C 1 101 ? 4.29421   27.45597  -14.02190 1.000 23.65654 ? 101 TRP C O   1 
ATOM   3053 C CB  . TRP C 1 101 ? 6.80448   25.67685  -13.50026 1.000 24.59582 ? 101 TRP C CB  1 
ATOM   3054 C CG  . TRP C 1 101 ? 8.11051   25.35467  -12.85531 1.000 24.71389 ? 101 TRP C CG  1 
ATOM   3055 C CD1 . TRP C 1 101 ? 8.83365   26.13162  -11.97590 1.000 23.68185 ? 101 TRP C CD1 1 
ATOM   3056 C CD2 . TRP C 1 101 ? 8.85508   24.15460  -13.02820 1.000 24.18936 ? 101 TRP C CD2 1 
ATOM   3057 N NE1 . TRP C 1 101 ? 9.97565   25.47415  -11.60582 1.000 20.93490 ? 101 TRP C NE1 1 
ATOM   3058 C CE2 . TRP C 1 101 ? 10.01207  24.26020  -12.23782 1.000 21.56379 ? 101 TRP C CE2 1 
ATOM   3059 C CE3 . TRP C 1 101 ? 8.65582   22.99660  -13.77776 1.000 23.36137 ? 101 TRP C CE3 1 
ATOM   3060 C CZ2 . TRP C 1 101 ? 10.95698  23.25731  -12.18118 1.000 26.33482 ? 101 TRP C CZ2 1 
ATOM   3061 C CZ3 . TRP C 1 101 ? 9.59289   22.00892  -13.71803 1.000 27.05115 ? 101 TRP C CZ3 1 
ATOM   3062 C CH2 . TRP C 1 101 ? 10.73278  22.14005  -12.92936 1.000 23.88006 ? 101 TRP C CH2 1 
ATOM   3063 N N   . VAL C 1 102 ? 5.38966   27.30971  -16.01276 1.000 21.41417 ? 102 VAL C N   1 
ATOM   3064 C CA  . VAL C 1 102 ? 4.19895   27.52768  -16.83729 1.000 20.90589 ? 102 VAL C CA  1 
ATOM   3065 C C   . VAL C 1 102 ? 4.22683   26.70619  -18.12395 1.000 21.51100 ? 102 VAL C C   1 
ATOM   3066 O O   . VAL C 1 102 ? 5.10779   26.89469  -18.97428 1.000 16.21852 ? 102 VAL C O   1 
ATOM   3067 C CB  . VAL C 1 102 ? 4.01745   29.00709  -17.21887 1.000 16.36838 ? 102 VAL C CB  1 
ATOM   3068 C CG1 . VAL C 1 102 ? 2.57116   29.40490  -17.04085 1.000 24.15334 ? 102 VAL C CG1 1 
ATOM   3069 C CG2 . VAL C 1 102 ? 4.93165   29.89254  -16.44819 1.000 18.82069 ? 102 VAL C CG2 1 
ATOM   3070 N N   . PHE C 1 103 ? 3.21841   25.85287  -18.30575 1.000 14.24129 ? 103 PHE C N   1 
ATOM   3071 C CA  . PHE C 1 103 ? 3.08832   25.00047  -19.48220 1.000 19.97328 ? 103 PHE C CA  1 
ATOM   3072 C C   . PHE C 1 103 ? 1.76680   25.31847  -20.18685 1.000 22.34200 ? 103 PHE C C   1 
ATOM   3073 O O   . PHE C 1 103 ? 0.71164   25.36892  -19.53661 1.000 18.21070 ? 103 PHE C O   1 
ATOM   3074 C CB  . PHE C 1 103 ? 3.12244   23.49751  -19.10094 1.000 17.22297 ? 103 PHE C CB  1 
ATOM   3075 C CG  . PHE C 1 103 ? 4.50217   22.95470  -18.74451 1.000 18.72623 ? 103 PHE C CG  1 
ATOM   3076 C CD1 . PHE C 1 103 ? 5.61232   23.78367  -18.66014 1.000 15.70184 ? 103 PHE C CD1 1 
ATOM   3077 C CD2 . PHE C 1 103 ? 4.67330   21.58825  -18.50412 1.000 17.34281 ? 103 PHE C CD2 1 
ATOM   3078 C CE1 . PHE C 1 103 ? 6.85504   23.27040  -18.32978 1.000 15.84919 ? 103 PHE C CE1 1 
ATOM   3079 C CE2 . PHE C 1 103 ? 5.92522   21.06605  -18.17571 1.000 18.33826 ? 103 PHE C CE2 1 
ATOM   3080 C CZ  . PHE C 1 103 ? 7.01288   21.91628  -18.08625 1.000 18.69503 ? 103 PHE C CZ  1 
ATOM   3081 N N   . PHE C 1 104 ? 1.81359   25.51825  -21.50489 1.000 13.51687 ? 104 PHE C N   1 
ATOM   3082 C CA  . PHE C 1 104 ? 0.59755   25.63384  -22.31030 1.000 19.95125 ? 104 PHE C CA  1 
ATOM   3083 C C   . PHE C 1 104 ? 0.47892   24.44239  -23.25900 1.000 25.66646 ? 104 PHE C C   1 
ATOM   3084 O O   . PHE C 1 104 ? 1.41448   24.15595  -24.02309 1.000 13.47109 ? 104 PHE C O   1 
ATOM   3085 C CB  . PHE C 1 104 ? 0.57308   26.94141  -23.09983 1.000 16.91811 ? 104 PHE C CB  1 
ATOM   3086 C CG  . PHE C 1 104 ? 0.61345   28.16663  -22.23189 1.000 24.51737 ? 104 PHE C CG  1 
ATOM   3087 C CD1 . PHE C 1 104 ? 1.11240   29.37065  -22.71867 1.000 16.87013 ? 104 PHE C CD1 1 
ATOM   3088 C CD2 . PHE C 1 104 ? 0.16958   28.10725  -20.91308 1.000 19.22959 ? 104 PHE C CD2 1 
ATOM   3089 C CE1 . PHE C 1 104 ? 1.14369   30.49132  -21.92130 1.000 19.22643 ? 104 PHE C CE1 1 
ATOM   3090 C CE2 . PHE C 1 104 ? 0.20557   29.21375  -20.10420 1.000 21.14868 ? 104 PHE C CE2 1 
ATOM   3091 C CZ  . PHE C 1 104 ? 0.69504   30.41910  -20.60569 1.000 18.71694 ? 104 PHE C CZ  1 
ATOM   3092 N N   . GLY C 1 105 ? -0.66242  23.74304  -23.18409 1.000 20.73758 ? 105 GLY C N   1 
ATOM   3093 C CA  . GLY C 1 105 ? -1.09219  22.81726  -24.21622 1.000 18.57830 ? 105 GLY C CA  1 
ATOM   3094 C C   . GLY C 1 105 ? -2.37117  23.32726  -24.85855 1.000 24.95599 ? 105 GLY C C   1 
ATOM   3095 O O   . GLY C 1 105 ? -3.20717  23.95209  -24.20168 1.000 21.90421 ? 105 GLY C O   1 
ATOM   3096 N N   . GLU C 1 106 ? -2.52739  23.07045  -26.14705 1.000 21.84294 ? 106 GLU C N   1 
ATOM   3097 C CA  . GLU C 1 106 ? -3.67892  23.57659  -26.86923 1.000 19.76100 ? 106 GLU C CA  1 
ATOM   3098 C C   . GLU C 1 106 ? -4.45386  22.43369  -27.50090 1.000 19.26151 ? 106 GLU C C   1 
ATOM   3099 O O   . GLU C 1 106 ? -3.93360  21.33787  -27.70587 1.000 22.86862 ? 106 GLU C O   1 
ATOM   3100 C CB  . GLU C 1 106 ? -3.26705  24.57943  -27.94975 1.000 26.52699 ? 106 GLU C CB  1 
ATOM   3101 C CG  . GLU C 1 106 ? -2.05440  25.44902  -27.60390 1.000 22.53320 ? 106 GLU C CG  1 
ATOM   3102 C CD  . GLU C 1 106 ? -0.95859  25.30321  -28.64604 1.000 19.14621 ? 106 GLU C CD  1 
ATOM   3103 O OE1 . GLU C 1 106 ? -0.83048  26.18043  -29.50594 1.000 22.80470 ? 106 GLU C OE1 1 
ATOM   3104 O OE2 . GLU C 1 106 ? -0.25838  24.28651  -28.64544 1.000 25.01109 ? 106 GLU C OE2 1 
ATOM   3105 N N   . MET C 1 107 ? -5.71314  22.71004  -27.81947 1.000 21.19173 ? 107 MET C N   1 
ATOM   3106 C CA  . MET C 1 107 ? -6.61617  21.69567  -28.33426 1.000 24.33693 ? 107 MET C CA  1 
ATOM   3107 C C   . MET C 1 107 ? -7.56494  22.32412  -29.34328 1.000 24.65916 ? 107 MET C C   1 
ATOM   3108 O O   . MET C 1 107 ? -7.86560  23.51829  -29.24986 1.000 24.03783 ? 107 MET C O   1 
ATOM   3109 C CB  . MET C 1 107 ? -7.41734  21.02735  -27.20950 1.000 19.00472 ? 107 MET C CB  1 
ATOM   3110 C CG  . MET C 1 107 ? -6.54829  20.47313  -26.08281 1.000 29.30710 ? 107 MET C CG  1 
ATOM   3111 S SD  . MET C 1 107 ? -7.49447  20.18825  -24.55123 1.000 34.26811 ? 107 MET C SD  1 
ATOM   3112 C CE  . MET C 1 107 ? -8.25068  21.76583  -24.12210 1.000 23.51745 ? 107 MET C CE  1 
ATOM   3113 N N   . PRO C 1 108 ? -8.01058  21.55463  -30.32655 1.000 22.69340 ? 108 PRO C N   1 
ATOM   3114 C CA  . PRO C 1 108 ? -9.05082  22.05153  -31.23595 1.000 22.38362 ? 108 PRO C CA  1 
ATOM   3115 C C   . PRO C 1 108 ? -10.22659 22.59652  -30.44430 1.000 24.91357 ? 108 PRO C C   1 
ATOM   3116 O O   . PRO C 1 108 ? -10.72998 21.95022  -29.52159 1.000 27.49677 ? 108 PRO C O   1 
ATOM   3117 C CB  . PRO C 1 108 ? -9.43421  20.80328  -32.04538 1.000 24.97967 ? 108 PRO C CB  1 
ATOM   3118 C CG  . PRO C 1 108 ? -8.16913  19.96176  -32.04215 1.000 22.81784 ? 108 PRO C CG  1 
ATOM   3119 C CD  . PRO C 1 108 ? -7.51705  20.21400  -30.69036 1.000 16.84236 ? 108 PRO C CD  1 
ATOM   3120 N N   . ALA C 1 109 ? -10.64777 23.81420  -30.79019 1.000 21.00296 ? 109 ALA C N   1 
ATOM   3121 C CA  . ALA C 1 109 ? -11.80721 24.39740  -30.13490 1.000 27.01399 ? 109 ALA C CA  1 
ATOM   3122 C C   . ALA C 1 109 ? -13.04511 23.52837  -30.30644 1.000 31.74058 ? 109 ALA C C   1 
ATOM   3123 O O   . ALA C 1 109 ? -14.00414 23.66952  -29.53897 1.000 32.38583 ? 109 ALA C O   1 
ATOM   3124 C CB  . ALA C 1 109 ? -12.05716 25.81199  -30.66876 1.000 29.87376 ? 109 ALA C CB  1 
ATOM   3125 N N   . GLN C 1 110 ? -13.02447 22.62290  -31.28851 1.000 29.49991 ? 110 GLN C N   1 
ATOM   3126 C CA  . GLN C 1 110 ? -14.11085 21.67899  -31.52122 1.000 27.08794 ? 110 GLN C CA  1 
ATOM   3127 C C   . GLN C 1 110 ? -14.30490 20.73094  -30.34600 1.000 22.09002 ? 110 GLN C C   1 
ATOM   3128 O O   . GLN C 1 110 ? -15.38426 20.16022  -30.18307 1.000 22.85709 ? 110 GLN C O   1 
ATOM   3129 C CB  . GLN C 1 110 ? -13.82351 20.88576  -32.80116 1.000 21.39666 ? 110 GLN C CB  1 
ATOM   3130 C CG  . GLN C 1 110 ? -14.04967 21.66944  -34.09321 1.000 27.97116 ? 110 GLN C CG  1 
ATOM   3131 C CD  . GLN C 1 110 ? -13.23298 22.95399  -34.19080 1.000 37.96114 ? 110 GLN C CD  1 
ATOM   3132 O OE1 . GLN C 1 110 ? -12.09937 23.04008  -33.68973 1.000 35.13552 ? 110 GLN C OE1 1 
ATOM   3133 N NE2 . GLN C 1 110 ? -13.80662 23.96378  -34.84761 1.000 35.85730 ? 110 GLN C NE2 1 
ATOM   3134 N N   . GLN C 1 111 ? -13.27785 20.52662  -29.53379 1.000 20.90302 ? 111 GLN C N   1 
ATOM   3135 C CA  . GLN C 1 111 ? -13.36822 19.63952  -28.37767 1.000 27.39336 ? 111 GLN C CA  1 
ATOM   3136 C C   . GLN C 1 111 ? -13.15297 20.40447  -27.08110 1.000 21.07021 ? 111 GLN C C   1 
ATOM   3137 O O   . GLN C 1 111 ? -12.55532 19.89815  -26.12740 1.000 27.78584 ? 111 GLN C O   1 
ATOM   3138 C CB  . GLN C 1 111 ? -12.37892 18.47997  -28.47916 1.000 18.98481 ? 111 GLN C CB  1 
ATOM   3139 C CG  . GLN C 1 111 ? -10.93335 18.87703  -28.73002 1.000 21.46742 ? 111 GLN C CG  1 
ATOM   3140 C CD  . GLN C 1 111 ? -10.15043 17.72486  -29.36316 1.000 20.73589 ? 111 GLN C CD  1 
ATOM   3141 O OE1 . GLN C 1 111 ? -10.39388 17.36426  -30.51148 1.000 11.17830 ? 111 GLN C OE1 1 
ATOM   3142 N NE2 . GLN C 1 111 ? -9.24890  17.10854  -28.58542 1.000 18.73420 ? 111 GLN C NE2 1 
ATOM   3143 N N   . MET C 1 112 ? -13.65223 21.63139  -27.02591 1.000 20.67700 ? 112 MET C N   1 
ATOM   3144 C CA  . MET C 1 112 ? -13.58981 22.42264  -25.80694 1.000 20.79203 ? 112 MET C CA  1 
ATOM   3145 C C   . MET C 1 112 ? -14.96860 23.00596  -25.54226 1.000 25.15251 ? 112 MET C C   1 
ATOM   3146 O O   . MET C 1 112 ? -15.48920 23.76164  -26.36477 1.000 24.09589 ? 112 MET C O   1 
ATOM   3147 C CB  . MET C 1 112 ? -12.51452 23.50641  -25.92335 1.000 22.41414 ? 112 MET C CB  1 
ATOM   3148 C CG  . MET C 1 112 ? -11.11319 22.90513  -26.02949 1.000 23.49538 ? 112 MET C CG  1 
ATOM   3149 S SD  . MET C 1 112 ? -9.76563  24.03765  -26.40612 1.000 31.64167 ? 112 MET C SD  1 
ATOM   3150 C CE  . MET C 1 112 ? -9.97419  25.26317  -25.11572 1.000 30.37999 ? 112 MET C CE  1 
ATOM   3151 N N   . VAL C 1 113 ? -15.56227 22.62269  -24.41336 1.000 20.22617 ? 113 VAL C N   1 
ATOM   3152 C CA  . VAL C 1 113 ? -16.86915 23.09594  -23.97805 1.000 22.54406 ? 113 VAL C CA  1 
ATOM   3153 C C   . VAL C 1 113 ? -16.69091 23.95974  -22.73600 1.000 27.92323 ? 113 VAL C C   1 
ATOM   3154 O O   . VAL C 1 113 ? -15.98773 23.57393  -21.79124 1.000 28.27886 ? 113 VAL C O   1 
ATOM   3155 C CB  . VAL C 1 113 ? -17.82592 21.92669  -23.69243 1.000 26.93340 ? 113 VAL C CB  1 
ATOM   3156 C CG1 . VAL C 1 113 ? -19.16999 22.45633  -23.19324 1.000 19.87980 ? 113 VAL C CG1 1 
ATOM   3157 C CG2 . VAL C 1 113 ? -17.99402 21.06219  -24.94360 1.000 22.31644 ? 113 VAL C CG2 1 
ATOM   3158 N N   . GLU C 1 114 ? -17.31762 25.12883  -22.74395 1.000 25.44593 ? 114 GLU C N   1 
ATOM   3159 C CA  . GLU C 1 114 ? -17.33852 26.03078  -21.60641 1.000 24.72377 ? 114 GLU C CA  1 
ATOM   3160 C C   . GLU C 1 114 ? -18.75444 26.57018  -21.46261 1.000 27.16475 ? 114 GLU C C   1 
ATOM   3161 O O   . GLU C 1 114 ? -19.40549 26.89377  -22.45703 1.000 23.11578 ? 114 GLU C O   1 
ATOM   3162 C CB  . GLU C 1 114 ? -16.32615 27.17478  -21.76399 1.000 28.53727 ? 114 GLU C CB  1 
ATOM   3163 C CG  . GLU C 1 114 ? -14.84980 26.72004  -21.84601 1.000 23.39109 ? 114 GLU C CG  1 
ATOM   3164 C CD  . GLU C 1 114 ? -13.86988 27.88222  -21.69405 1.000 28.54324 ? 114 GLU C CD  1 
ATOM   3165 O OE1 . GLU C 1 114 ? -14.32715 29.03013  -21.50898 1.000 33.03330 ? 114 GLU C OE1 1 
ATOM   3166 O OE2 . GLU C 1 114 ? -12.64190 27.67045  -21.73699 1.000 25.46553 ? 114 GLU C OE2 1 
ATOM   3167 N N   . TYR C 1 115 ? -19.24584 26.61787  -20.22302 1.000 31.57811 ? 115 TYR C N   1 
ATOM   3168 C CA  . TYR C 1 115 ? -20.62476 27.02632  -19.93889 1.000 32.08890 ? 115 TYR C CA  1 
ATOM   3169 C C   . TYR C 1 115 ? -21.65908 26.20660  -20.71690 1.000 35.53868 ? 115 TYR C C   1 
ATOM   3170 O O   . TYR C 1 115 ? -22.75709 26.69530  -21.00425 1.000 38.67435 ? 115 TYR C O   1 
ATOM   3171 C CB  . TYR C 1 115 ? -20.83120 28.51695  -20.22260 1.000 33.14082 ? 115 TYR C CB  1 
ATOM   3172 C CG  . TYR C 1 115 ? -20.03703 29.43847  -19.33187 1.000 27.70057 ? 115 TYR C CG  1 
ATOM   3173 C CD1 . TYR C 1 115 ? -18.79647 29.90994  -19.71526 1.000 28.33188 ? 115 TYR C CD1 1 
ATOM   3174 C CD2 . TYR C 1 115 ? -20.54161 29.83834  -18.10642 1.000 40.64224 ? 115 TYR C CD2 1 
ATOM   3175 C CE1 . TYR C 1 115 ? -18.08226 30.75755  -18.90274 1.000 31.62321 ? 115 TYR C CE1 1 
ATOM   3176 C CE2 . TYR C 1 115 ? -19.84141 30.67863  -17.28424 1.000 38.53171 ? 115 TYR C CE2 1 
ATOM   3177 C CZ  . TYR C 1 115 ? -18.61806 31.13848  -17.68231 1.000 35.39741 ? 115 TYR C CZ  1 
ATOM   3178 O OH  . TYR C 1 115 ? -17.95011 31.97838  -16.83767 1.000 28.14373 ? 115 TYR C OH  1 
ATOM   3179 N N   . GLY C 1 116 ? -21.33464 24.96078  -21.06261 1.000 34.08331 ? 116 GLY C N   1 
ATOM   3180 C CA  . GLY C 1 116 ? -22.21808 24.16081  -21.89458 1.000 30.50260 ? 116 GLY C CA  1 
ATOM   3181 C C   . GLY C 1 116 ? -22.19175 24.47589  -23.37857 1.000 29.99802 ? 116 GLY C C   1 
ATOM   3182 O O   . GLY C 1 116 ? -23.11464 24.08522  -24.10178 1.000 29.02720 ? 116 GLY C O   1 
ATOM   3183 N N   . ARG C 1 117 ? -21.15872 25.15721  -23.86668 1.000 23.95792 ? 117 ARG C N   1 
ATOM   3184 C CA  . ARG C 1 117 ? -21.10681 25.57104  -25.26248 1.000 33.04114 ? 117 ARG C CA  1 
ATOM   3185 C C   . ARG C 1 117 ? -19.71703 25.31353  -25.82440 1.000 31.58804 ? 117 ARG C C   1 
ATOM   3186 O O   . ARG C 1 117 ? -18.72008 25.32720  -25.09692 1.000 27.59926 ? 117 ARG C O   1 
ATOM   3187 C CB  . ARG C 1 117 ? -21.46649 27.06056  -25.44379 1.000 35.17542 ? 117 ARG C CB  1 
ATOM   3188 C CG  . ARG C 1 117 ? -22.85291 27.43048  -24.97087 1.000 36.49844 ? 117 ARG C CG  1 
ATOM   3189 C CD  . ARG C 1 117 ? -23.93251 26.73356  -25.77295 1.000 35.09624 ? 117 ARG C CD  1 
ATOM   3190 N NE  . ARG C 1 117 ? -24.57271 27.61531  -26.74292 1.000 44.79203 ? 117 ARG C NE  1 
ATOM   3191 C CZ  . ARG C 1 117 ? -25.69704 27.32982  -27.38751 1.000 46.91849 ? 117 ARG C CZ  1 
ATOM   3192 N NH1 . ARG C 1 117 ? -26.35754 26.20424  -27.16206 1.000 50.68334 ? 117 ARG C NH1 1 
ATOM   3193 N NH2 . ARG C 1 117 ? -26.17326 28.19630  -28.27729 1.000 53.19707 ? 117 ARG C NH2 1 
ATOM   3194 N N   . PHE C 1 118 ? -19.65750 25.09829  -27.13429 1.000 31.51832 ? 118 PHE C N   1 
ATOM   3195 C CA  . PHE C 1 118 ? -18.39664 24.74110  -27.76773 1.000 31.31115 ? 118 PHE C CA  1 
ATOM   3196 C C   . PHE C 1 118 ? -17.61887 25.99249  -28.12104 1.000 29.95394 ? 118 PHE C C   1 
ATOM   3197 O O   . PHE C 1 118 ? -18.16225 26.91644  -28.73284 1.000 32.53961 ? 118 PHE C O   1 
ATOM   3198 C CB  . PHE C 1 118 ? -18.63689 23.89313  -29.01265 1.000 26.94270 ? 118 PHE C CB  1 
ATOM   3199 C CG  . PHE C 1 118 ? -18.78997 22.44265  -28.71594 1.000 29.64772 ? 118 PHE C CG  1 
ATOM   3200 C CD1 . PHE C 1 118 ? -17.67666 21.61985  -28.63039 1.000 27.21983 ? 118 PHE C CD1 1 
ATOM   3201 C CD2 . PHE C 1 118 ? -20.04194 21.89950  -28.49475 1.000 29.17265 ? 118 PHE C CD2 1 
ATOM   3202 C CE1 . PHE C 1 118 ? -17.81795 20.26913  -28.35282 1.000 28.58797 ? 118 PHE C CE1 1 
ATOM   3203 C CE2 . PHE C 1 118 ? -20.18821 20.54652  -28.21399 1.000 34.47911 ? 118 PHE C CE2 1 
ATOM   3204 C CZ  . PHE C 1 118 ? -19.06889 19.73335  -28.14520 1.000 29.24281 ? 118 PHE C CZ  1 
ATOM   3205 N N   . LEU C 1 119 ? -16.34408 26.01083  -27.74636 1.000 29.63908 ? 119 LEU C N   1 
ATOM   3206 C CA  . LEU C 1 119 ? -15.51496 27.16996  -28.01919 1.000 28.89604 ? 119 LEU C CA  1 
ATOM   3207 C C   . LEU C 1 119 ? -15.43095 27.42304  -29.52456 1.000 33.19458 ? 119 LEU C C   1 
ATOM   3208 O O   . LEU C 1 119 ? -15.39660 26.47516  -30.32423 1.000 22.03708 ? 119 LEU C O   1 
ATOM   3209 C CB  . LEU C 1 119 ? -14.11849 26.99658  -27.41936 1.000 21.71618 ? 119 LEU C CB  1 
ATOM   3210 C CG  . LEU C 1 119 ? -14.12446 27.28071  -25.91065 1.000 29.14373 ? 119 LEU C CG  1 
ATOM   3211 C CD1 . LEU C 1 119 ? -12.72959 27.50141  -25.34292 1.000 27.25505 ? 119 LEU C CD1 1 
ATOM   3212 C CD2 . LEU C 1 119 ? -15.02962 28.47339  -25.58701 1.000 29.46518 ? 119 LEU C CD2 1 
ATOM   3213 N N   . PRO C 1 120 ? -15.44356 28.67607  -29.94181 1.000 30.86705 ? 120 PRO C N   1 
ATOM   3214 C CA  . PRO C 1 120 ? -15.20002 28.99105  -31.35021 1.000 24.66980 ? 120 PRO C CA  1 
ATOM   3215 C C   . PRO C 1 120 ? -13.72031 29.19728  -31.62021 1.000 33.11967 ? 120 PRO C C   1 
ATOM   3216 O O   . PRO C 1 120 ? -12.87331 28.81929  -30.80418 1.000 31.32869 ? 120 PRO C O   1 
ATOM   3217 C CB  . PRO C 1 120 ? -15.99983 30.27742  -31.54789 1.000 35.04430 ? 120 PRO C CB  1 
ATOM   3218 C CG  . PRO C 1 120 ? -15.85911 30.97316  -30.23553 1.000 33.97102 ? 120 PRO C CG  1 
ATOM   3219 C CD  . PRO C 1 120 ? -15.90224 29.84989  -29.18065 1.000 28.86015 ? 120 PRO C CD  1 
ATOM   3220 N N   . GLN C 1 121 ? -13.38514 29.77558  -32.74477 1.000 33.38055 ? 121 GLN C N   1 
ATOM   3221 C CA  . GLN C 1 121 ? -11.96288 30.03127  -32.85771 1.000 33.54951 ? 121 GLN C CA  1 
ATOM   3222 C C   . GLN C 1 121 ? -11.63818 31.42010  -32.32823 1.000 40.49337 ? 121 GLN C C   1 
ATOM   3223 O O   . GLN C 1 121 ? -12.54276 32.22732  -32.07092 1.000 41.89696 ? 121 GLN C O   1 
ATOM   3224 C CB  . GLN C 1 121 ? -11.53728 29.89069  -34.30133 1.000 26.86764 ? 121 GLN C CB  1 
ATOM   3225 C CG  . GLN C 1 121 ? -12.19994 28.71963  -34.97996 1.000 31.21406 ? 121 GLN C CG  1 
ATOM   3226 C CD  . GLN C 1 121 ? -11.39183 27.43907  -34.85002 1.000 33.14632 ? 121 GLN C CD  1 
ATOM   3227 O OE1 . GLN C 1 121 ? -11.93766 26.33878  -34.88283 1.000 36.47183 ? 121 GLN C OE1 1 
ATOM   3228 N NE2 . GLN C 1 121 ? -10.08226 27.57948  -34.71681 1.000 37.48433 ? 121 GLN C NE2 1 
ATOM   3229 N N   . PRO C 1 122 ? -10.34653 31.72586  -32.11264 1.000 41.92388 ? 122 PRO C N   1 
ATOM   3230 C CA  . PRO C 1 122 ? -9.94975  33.12736  -31.88781 1.000 39.84097 ? 122 PRO C CA  1 
ATOM   3231 C C   . PRO C 1 122 ? -10.50652 34.08342  -32.93831 1.000 48.75172 ? 122 PRO C C   1 
ATOM   3232 O O   . PRO C 1 122 ? -10.64545 35.28880  -32.68482 1.000 46.60410 ? 122 PRO C O   1 
ATOM   3233 C CB  . PRO C 1 122 ? -8.41668  33.06492  -31.94096 1.000 27.85070 ? 122 PRO C CB  1 
ATOM   3234 C CG  . PRO C 1 122 ? -8.09639  31.72229  -31.39523 1.000 34.89349 ? 122 PRO C CG  1 
ATOM   3235 C CD  . PRO C 1 122 ? -9.25941  30.79118  -31.75939 1.000 39.39162 ? 122 PRO C CD  1 
ATOM   3236 N N   . GLY C 1 123 ? -10.81079 33.55661  -34.12989 1.000 46.72938 ? 123 GLY C N   1 
ATOM   3237 C CA  . GLY C 1 123 ? -11.46963 34.33082  -35.16424 1.000 41.62766 ? 123 GLY C CA  1 
ATOM   3238 C C   . GLY C 1 123 ? -12.98660 34.30417  -35.10012 1.000 51.48622 ? 123 GLY C C   1 
ATOM   3239 O O   . GLY C 1 123 ? -13.63628 34.09042  -36.13229 1.000 49.87908 ? 123 GLY C O   1 
ATOM   3240 N N   . HIS C 1 124 ? -13.57189 34.52044  -33.91063 1.000 46.50466 ? 124 HIS C N   1 
ATOM   3241 C CA  . HIS C 1 124 ? -15.03038 34.46621  -33.80840 1.000 50.53408 ? 124 HIS C CA  1 
ATOM   3242 C C   . HIS C 1 124 ? -15.64623 34.93969  -32.49368 1.000 42.61846 ? 124 HIS C C   1 
ATOM   3243 O O   . HIS C 1 124 ? -16.84482 35.22856  -32.45952 1.000 43.82103 ? 124 HIS C O   1 
ATOM   3244 C CB  . HIS C 1 124 ? -15.51600 33.03422  -34.05281 1.000 51.56682 ? 124 HIS C CB  1 
ATOM   3245 C CG  . HIS C 1 124 ? -17.00634 32.90889  -34.15107 1.000 50.19321 ? 124 HIS C CG  1 
ATOM   3246 N ND1 . HIS C 1 124 ? -17.75800 32.21457  -33.22836 1.000 44.22586 ? 124 HIS C ND1 1 
ATOM   3247 C CD2 . HIS C 1 124 ? -17.88498 33.39343  -35.06252 1.000 54.78119 ? 124 HIS C CD2 1 
ATOM   3248 C CE1 . HIS C 1 124 ? -19.03281 32.26081  -33.57382 1.000 46.24846 ? 124 HIS C CE1 1 
ATOM   3249 N NE2 . HIS C 1 124 ? -19.13826 32.97846  -34.67772 1.000 50.52969 ? 124 HIS C NE2 1 
ATOM   3250 N N   . GLU C 1 125 ? -14.85713 35.03483  -31.41848 1.000 42.45003 ? 125 GLU C N   1 
ATOM   3251 C CA  . GLU C 1 125 ? -15.42223 34.98526  -30.06604 1.000 40.38436 ? 125 GLU C CA  1 
ATOM   3252 C C   . GLU C 1 125 ? -16.48948 36.04402  -29.79111 1.000 45.39880 ? 125 GLU C C   1 
ATOM   3253 O O   . GLU C 1 125 ? -17.29171 35.87912  -28.86346 1.000 36.63920 ? 125 GLU C O   1 
ATOM   3254 C CB  . GLU C 1 125 ? -14.31139 35.12143  -29.03129 1.000 46.26307 ? 125 GLU C CB  1 
ATOM   3255 C CG  . GLU C 1 125 ? -13.46490 36.35316  -29.20800 1.000 51.67759 ? 125 GLU C CG  1 
ATOM   3256 C CD  . GLU C 1 125 ? -12.01537 36.00628  -29.41597 1.000 40.41294 ? 125 GLU C CD  1 
ATOM   3257 O OE1 . GLU C 1 125 ? -11.67684 34.81511  -29.27989 1.000 38.21567 ? 125 GLU C OE1 1 
ATOM   3258 O OE2 . GLU C 1 125 ? -11.22139 36.91855  -29.71979 1.000 40.66153 ? 125 GLU C OE2 1 
ATOM   3259 N N   . GLY C 1 126 ? -16.50325 37.14114  -30.55376 1.000 48.13808 ? 126 GLY C N   1 
ATOM   3260 C CA  . GLY C 1 126 ? -17.49556 38.19522  -30.38055 1.000 43.47002 ? 126 GLY C CA  1 
ATOM   3261 C C   . GLY C 1 126 ? -18.80570 37.91515  -31.08962 1.000 43.72731 ? 126 GLY C C   1 
ATOM   3262 O O   . GLY C 1 126 ? -19.88769 38.11183  -30.52851 1.000 43.41093 ? 126 GLY C O   1 
ATOM   3263 N N   . GLU C 1 127 ? -18.70745 37.47188  -32.34404 1.000 41.37100 ? 127 GLU C N   1 
ATOM   3264 C CA  . GLU C 1 127 ? -19.84793 36.87870  -33.02753 1.000 39.89746 ? 127 GLU C CA  1 
ATOM   3265 C C   . GLU C 1 127 ? -20.44118 35.73733  -32.20783 1.000 40.34160 ? 127 GLU C C   1 
ATOM   3266 O O   . GLU C 1 127 ? -21.66314 35.55482  -32.16671 1.000 43.34944 ? 127 GLU C O   1 
ATOM   3267 C CB  . GLU C 1 127 ? -19.38800 36.37169  -34.39231 1.000 45.49110 ? 127 GLU C CB  1 
ATOM   3268 C CG  . GLU C 1 127 ? -20.28752 36.66162  -35.56415 1.000 47.37113 ? 127 GLU C CG  1 
ATOM   3269 C CD  . GLU C 1 127 ? -19.51688 36.56300  -36.86414 1.000 55.57729 ? 127 GLU C CD  1 
ATOM   3270 O OE1 . GLU C 1 127 ? -18.35476 37.03058  -36.88929 1.000 48.03434 ? 127 GLU C OE1 1 
ATOM   3271 O OE2 . GLU C 1 127 ? -20.05235 36.00305  -37.84455 1.000 48.77961 ? 127 GLU C OE2 1 
ATOM   3272 N N   . TRP C 1 128 ? -19.57576 34.96335  -31.54301 1.000 41.14305 ? 128 TRP C N   1 
ATOM   3273 C CA  . TRP C 1 128 ? -20.00616 33.82396  -30.73313 1.000 40.37899 ? 128 TRP C CA  1 
ATOM   3274 C C   . TRP C 1 128 ? -20.84241 34.27537  -29.54507 1.000 38.61033 ? 128 TRP C C   1 
ATOM   3275 O O   . TRP C 1 128 ? -21.96519 33.79893  -29.34119 1.000 35.87546 ? 128 TRP C O   1 
ATOM   3276 C CB  . TRP C 1 128 ? -18.77599 33.04674  -30.24913 1.000 38.10382 ? 128 TRP C CB  1 
ATOM   3277 C CG  . TRP C 1 128 ? -19.05097 31.67802  -29.68554 1.000 34.82621 ? 128 TRP C CG  1 
ATOM   3278 C CD1 . TRP C 1 128 ? -19.42999 30.56607  -30.38329 1.000 37.59530 ? 128 TRP C CD1 1 
ATOM   3279 C CD2 . TRP C 1 128 ? -18.91184 31.26349  -28.31975 1.000 29.29877 ? 128 TRP C CD2 1 
ATOM   3280 N NE1 . TRP C 1 128 ? -19.56185 29.49258  -29.53149 1.000 34.42559 ? 128 TRP C NE1 1 
ATOM   3281 C CE2 . TRP C 1 128 ? -19.24324 29.89362  -28.26118 1.000 31.25251 ? 128 TRP C CE2 1 
ATOM   3282 C CE3 . TRP C 1 128 ? -18.55083 31.91843  -27.14223 1.000 33.94883 ? 128 TRP C CE3 1 
ATOM   3283 C CZ2 . TRP C 1 128 ? -19.23369 29.17427  -27.07193 1.000 29.80096 ? 128 TRP C CZ2 1 
ATOM   3284 C CZ3 . TRP C 1 128 ? -18.53810 31.20518  -25.96238 1.000 27.76861 ? 128 TRP C CZ3 1 
ATOM   3285 C CH2 . TRP C 1 128 ? -18.87633 29.84316  -25.93612 1.000 35.17086 ? 128 TRP C CH2 1 
ATOM   3286 N N   . PHE C 1 129 ? -20.29231 35.18787  -28.74270 1.000 38.88055 ? 129 PHE C N   1 
ATOM   3287 C CA  . PHE C 1 129 ? -20.98004 35.68301  -27.55478 1.000 45.33280 ? 129 PHE C CA  1 
ATOM   3288 C C   . PHE C 1 129 ? -22.38214 36.17819  -27.87769 1.000 40.65409 ? 129 PHE C C   1 
ATOM   3289 O O   . PHE C 1 129 ? -23.31421 35.97900  -27.09250 1.000 45.77232 ? 129 PHE C O   1 
ATOM   3290 C CB  . PHE C 1 129 ? -20.14236 36.79762  -26.92032 1.000 41.49400 ? 129 PHE C CB  1 
ATOM   3291 C CG  . PHE C 1 129 ? -20.90310 37.70488  -25.98962 1.000 43.92837 ? 129 PHE C CG  1 
ATOM   3292 C CD1 . PHE C 1 129 ? -20.83713 37.51865  -24.61947 1.000 48.13760 ? 129 PHE C CD1 1 
ATOM   3293 C CD2 . PHE C 1 129 ? -21.64821 38.77213  -26.48104 1.000 45.86585 ? 129 PHE C CD2 1 
ATOM   3294 C CE1 . PHE C 1 129 ? -21.51890 38.36061  -23.75421 1.000 48.00018 ? 129 PHE C CE1 1 
ATOM   3295 C CE2 . PHE C 1 129 ? -22.33805 39.61060  -25.62322 1.000 46.57638 ? 129 PHE C CE2 1 
ATOM   3296 C CZ  . PHE C 1 129 ? -22.26537 39.40954  -24.26174 1.000 47.88871 ? 129 PHE C CZ  1 
ATOM   3297 N N   . ASP C 1 130 ? -22.55786 36.80741  -29.03822 1.000 42.26530 ? 130 ASP C N   1 
ATOM   3298 C CA  . ASP C 1 130 ? -23.79301 37.54960  -29.27833 1.000 48.27030 ? 130 ASP C CA  1 
ATOM   3299 C C   . ASP C 1 130 ? -24.98952 36.63997  -29.48685 1.000 48.81768 ? 130 ASP C C   1 
ATOM   3300 O O   . ASP C 1 130 ? -26.11148 37.00700  -29.11928 1.000 49.03215 ? 130 ASP C O   1 
ATOM   3301 C CB  . ASP C 1 130 ? -23.62866 38.47160  -30.47928 1.000 37.29665 ? 130 ASP C CB  1 
ATOM   3302 C CG  . ASP C 1 130 ? -22.89761 39.72804  -30.12578 1.000 35.71281 ? 130 ASP C CG  1 
ATOM   3303 O OD1 . ASP C 1 130 ? -22.97350 40.11646  -28.94418 1.000 36.96628 ? 130 ASP C OD1 1 
ATOM   3304 O OD2 . ASP C 1 130 ? -22.26013 40.32501  -31.01570 1.000 39.35547 ? 130 ASP C OD2 1 
ATOM   3305 N N   . ASN C 1 131 ? -24.78054 35.46497  -30.06094 1.000 46.25909 ? 131 ASN C N   1 
ATOM   3306 C CA  . ASN C 1 131 ? -25.90450 34.63780  -30.47848 1.000 42.24815 ? 131 ASN C CA  1 
ATOM   3307 C C   . ASN C 1 131 ? -26.13989 33.49056  -29.51087 1.000 49.07338 ? 131 ASN C C   1 
ATOM   3308 O O   . ASN C 1 131 ? -26.33810 32.34108  -29.89647 1.000 46.92017 ? 131 ASN C O   1 
ATOM   3309 C CB  . ASN C 1 131 ? -25.67381 34.15964  -31.89872 1.000 47.47245 ? 131 ASN C CB  1 
ATOM   3310 C CG  . ASN C 1 131 ? -25.56185 35.32024  -32.86675 1.000 52.09005 ? 131 ASN C CG  1 
ATOM   3311 O OD1 . ASN C 1 131 ? -25.89412 36.46185  -32.51816 1.000 48.25686 ? 131 ASN C OD1 1 
ATOM   3312 N ND2 . ASN C 1 131 ? -25.09248 35.04654  -34.07993 1.000 54.72051 ? 131 ASN C ND2 1 
ATOM   3313 N N   . LEU C 1 132 ? -26.12893 33.83167  -28.22499 1.000 49.63989 ? 132 LEU C N   1 
ATOM   3314 C CA  . LEU C 1 132 ? -26.47207 32.92599  -27.14112 1.000 52.66604 ? 132 LEU C CA  1 
ATOM   3315 C C   . LEU C 1 132 ? -27.84259 33.29476  -26.57962 1.000 48.00713 ? 132 LEU C C   1 
ATOM   3316 O O   . LEU C 1 132 ? -28.27524 34.44462  -26.67112 1.000 54.15446 ? 132 LEU C O   1 
ATOM   3317 C CB  . LEU C 1 132 ? -25.41903 32.98242  -26.02303 1.000 52.36338 ? 132 LEU C CB  1 
ATOM   3318 C CG  . LEU C 1 132 ? -23.93810 32.73387  -26.33917 1.000 49.62040 ? 132 LEU C CG  1 
ATOM   3319 C CD1 . LEU C 1 132 ? -23.09401 33.32599  -25.23288 1.000 41.11905 ? 132 LEU C CD1 1 
ATOM   3320 C CD2 . LEU C 1 132 ? -23.61457 31.24422  -26.53095 1.000 42.01726 ? 132 LEU C CD2 1 
ATOM   3321 N N   . SER C 1 133 ? -28.53703 32.30637  -26.01839 1.000 43.66433 ? 133 SER C N   1 
ATOM   3322 C CA  . SER C 1 133 ? -29.78979 32.58846  -25.32826 1.000 55.01289 ? 133 SER C CA  1 
ATOM   3323 C C   . SER C 1 133 ? -29.53483 33.52668  -24.15643 1.000 56.35738 ? 133 SER C C   1 
ATOM   3324 O O   . SER C 1 133 ? -28.51407 33.42201  -23.47267 1.000 55.63808 ? 133 SER C O   1 
ATOM   3325 C CB  . SER C 1 133 ? -30.44373 31.30000  -24.82991 1.000 56.31948 ? 133 SER C CB  1 
ATOM   3326 O OG  . SER C 1 133 ? -31.67336 31.57666  -24.17624 1.000 51.14793 ? 133 SER C OG  1 
ATOM   3327 N N   . SER C 1 134 ? -30.47823 34.44291  -23.92752 1.000 53.16649 ? 134 SER C N   1 
ATOM   3328 C CA  . SER C 1 134 ? -30.34666 35.51960  -22.94792 1.000 50.96899 ? 134 SER C CA  1 
ATOM   3329 C C   . SER C 1 134 ? -29.74494 35.06309  -21.62041 1.000 46.29287 ? 134 SER C C   1 
ATOM   3330 O O   . SER C 1 134 ? -28.87740 35.74900  -21.06803 1.000 45.02785 ? 134 SER C O   1 
ATOM   3331 C CB  . SER C 1 134 ? -31.71585 36.17347  -22.71355 1.000 50.26676 ? 134 SER C CB  1 
ATOM   3332 O OG  . SER C 1 134 ? -32.63948 35.28948  -22.08592 1.000 46.96377 ? 134 SER C OG  1 
ATOM   3333 N N   . ASP C 1 135 ? -30.19039 33.90717  -21.11200 1.000 45.67030 ? 135 ASP C N   1 
ATOM   3334 C CA  . ASP C 1 135 ? -29.63869 33.36793  -19.87063 1.000 51.10580 ? 135 ASP C CA  1 
ATOM   3335 C C   . ASP C 1 135 ? -28.13571 33.14591  -19.99471 1.000 45.54488 ? 135 ASP C C   1 
ATOM   3336 O O   . ASP C 1 135 ? -27.36041 33.61604  -19.15515 1.000 45.80308 ? 135 ASP C O   1 
ATOM   3337 C CB  . ASP C 1 135 ? -30.35886 32.06237  -19.49162 1.000 51.34236 ? 135 ASP C CB  1 
ATOM   3338 C CG  . ASP C 1 135 ? -30.04945 31.59341  -18.05343 1.000 58.94574 ? 135 ASP C CG  1 
ATOM   3339 O OD1 . ASP C 1 135 ? -29.39085 32.34247  -17.29442 1.000 58.89338 ? 135 ASP C OD1 1 
ATOM   3340 O OD2 . ASP C 1 135 ? -30.46697 30.46744  -17.67913 1.000 53.46667 ? 135 ASP C OD2 1 
ATOM   3341 N N   . GLU C 1 136 ? -27.70714 32.43729  -21.04615 1.000 47.06955 ? 136 GLU C N   1 
ATOM   3342 C CA  . GLU C 1 136 ? -26.28955 32.12584  -21.22882 1.000 46.56437 ? 136 GLU C CA  1 
ATOM   3343 C C   . GLU C 1 136 ? -25.44309 33.39159  -21.20793 1.000 47.13671 ? 136 GLU C C   1 
ATOM   3344 O O   . GLU C 1 136 ? -24.47118 33.49983  -20.45082 1.000 43.98229 ? 136 GLU C O   1 
ATOM   3345 C CB  . GLU C 1 136 ? -26.06476 31.37927  -22.55188 1.000 49.87127 ? 136 GLU C CB  1 
ATOM   3346 C CG  . GLU C 1 136 ? -26.96464 30.18631  -22.84213 1.000 38.88321 ? 136 GLU C CG  1 
ATOM   3347 C CD  . GLU C 1 136 ? -26.68777 29.59572  -24.22051 1.000 46.47780 ? 136 GLU C CD  1 
ATOM   3348 O OE1 . GLU C 1 136 ? -25.71038 28.83563  -24.35868 1.000 40.15191 ? 136 GLU C OE1 1 
ATOM   3349 O OE2 . GLU C 1 136 ? -27.43067 29.90393  -25.17595 1.000 48.75200 ? 136 GLU C OE2 1 
ATOM   3350 N N   . ARG C 1 137 ? -25.80106 34.35757  -22.05150 1.000 49.53673 ? 137 ARG C N   1 
ATOM   3351 C CA  . ARG C 1 137 ? -25.07722 35.62015  -22.09843 1.000 47.96754 ? 137 ARG C CA  1 
ATOM   3352 C C   . ARG C 1 137 ? -25.03477 36.27693  -20.72334 1.000 44.73221 ? 137 ARG C C   1 
ATOM   3353 O O   . ARG C 1 137 ? -23.97986 36.73666  -20.27182 1.000 43.35748 ? 137 ARG C O   1 
ATOM   3354 C CB  . ARG C 1 137 ? -25.73875 36.53794  -23.12434 1.000 43.51235 ? 137 ARG C CB  1 
ATOM   3355 C CG  . ARG C 1 137 ? -24.97596 37.79119  -23.40906 1.000 49.67442 ? 137 ARG C CG  1 
ATOM   3356 C CD  . ARG C 1 137 ? -25.72051 38.68388  -24.37499 1.000 43.88470 ? 137 ARG C CD  1 
ATOM   3357 N NE  . ARG C 1 137 ? -26.22808 37.91586  -25.50563 1.000 50.73382 ? 137 ARG C NE  1 
ATOM   3358 C CZ  . ARG C 1 137 ? -27.49820 37.87807  -25.88245 1.000 45.90301 ? 137 ARG C CZ  1 
ATOM   3359 N NH1 . ARG C 1 137 ? -28.42690 38.58509  -25.25896 1.000 42.18016 ? 137 ARG C NH1 1 
ATOM   3360 N NH2 . ARG C 1 137 ? -27.84155 37.12581  -26.92315 1.000 42.38134 ? 137 ARG C NH2 1 
ATOM   3361 N N   . ALA C 1 138 ? -26.17232 36.29822  -20.02607 1.000 45.31098 ? 138 ALA C N   1 
ATOM   3362 C CA  . ALA C 1 138 ? -26.25481 37.03444  -18.76677 1.000 44.91783 ? 138 ALA C CA  1 
ATOM   3363 C C   . ALA C 1 138 ? -25.46361 36.35200  -17.65136 1.000 42.32908 ? 138 ALA C C   1 
ATOM   3364 O O   . ALA C 1 138 ? -24.79034 37.03353  -16.86835 1.000 41.58375 ? 138 ALA C O   1 
ATOM   3365 C CB  . ALA C 1 138 ? -27.71787 37.22209  -18.36100 1.000 43.33556 ? 138 ALA C CB  1 
ATOM   3366 N N   . PHE C 1 139 ? -25.53245 35.01450  -17.55078 1.000 42.04734 ? 139 PHE C N   1 
ATOM   3367 C CA  . PHE C 1 139 ? -24.73826 34.31727  -16.53680 1.000 43.74976 ? 139 PHE C CA  1 
ATOM   3368 C C   . PHE C 1 139 ? -23.25318 34.58445  -16.73509 1.000 41.59233 ? 139 PHE C C   1 
ATOM   3369 O O   . PHE C 1 139 ? -22.50685 34.75203  -15.76426 1.000 45.04893 ? 139 PHE C O   1 
ATOM   3370 C CB  . PHE C 1 139 ? -25.02055 32.80722  -16.55662 1.000 43.09019 ? 139 PHE C CB  1 
ATOM   3371 C CG  . PHE C 1 139 ? -24.61420 32.08472  -15.28027 1.000 40.00867 ? 139 PHE C CG  1 
ATOM   3372 C CD1 . PHE C 1 139 ? -23.34897 32.24033  -14.73707 1.000 46.37651 ? 139 PHE C CD1 1 
ATOM   3373 C CD2 . PHE C 1 139 ? -25.50131 31.25614  -14.62292 1.000 47.54442 ? 139 PHE C CD2 1 
ATOM   3374 C CE1 . PHE C 1 139 ? -22.97309 31.59862  -13.57454 1.000 40.44186 ? 139 PHE C CE1 1 
ATOM   3375 C CE2 . PHE C 1 139 ? -25.12875 30.59790  -13.44865 1.000 46.78421 ? 139 PHE C CE2 1 
ATOM   3376 C CZ  . PHE C 1 139 ? -23.85872 30.77689  -12.92648 1.000 39.79288 ? 139 PHE C CZ  1 
ATOM   3377 N N   . MET C 1 140 ? -22.80519 34.64114  -17.98464 1.000 43.13404 ? 140 MET C N   1 
ATOM   3378 C CA  . MET C 1 140 ? -21.40163 34.93540  -18.22104 1.000 43.33194 ? 140 MET C CA  1 
ATOM   3379 C C   . MET C 1 140 ? -21.05068 36.35707  -17.79073 1.000 39.64861 ? 140 MET C C   1 
ATOM   3380 O O   . MET C 1 140 ? -19.94604 36.58795  -17.28615 1.000 35.98485 ? 140 MET C O   1 
ATOM   3381 C CB  . MET C 1 140 ? -21.06881 34.68179  -19.69287 1.000 45.04869 ? 140 MET C CB  1 
ATOM   3382 C CG  . MET C 1 140 ? -20.89853 33.19441  -20.04137 1.000 38.07311 ? 140 MET C CG  1 
ATOM   3383 S SD  . MET C 1 140 ? -20.69774 32.92847  -21.82523 1.000 42.65927 ? 140 MET C SD  1 
ATOM   3384 C CE  . MET C 1 140 ? -21.45589 34.43135  -22.43605 1.000 46.12863 ? 140 MET C CE  1 
ATOM   3385 N N   . GLU C 1 141 ? -21.99003 37.30604  -17.93325 1.000 42.23406 ? 141 GLU C N   1 
ATOM   3386 C CA  . GLU C 1 141 ? -21.71998 38.69450  -17.55570 1.000 42.69450 ? 141 GLU C CA  1 
ATOM   3387 C C   . GLU C 1 141 ? -21.42780 38.85146  -16.07188 1.000 43.01948 ? 141 GLU C C   1 
ATOM   3388 O O   . GLU C 1 141 ? -20.69752 39.76917  -15.67756 1.000 49.14748 ? 141 GLU C O   1 
ATOM   3389 C CB  . GLU C 1 141 ? -22.89207 39.59191  -17.93074 1.000 42.87837 ? 141 GLU C CB  1 
ATOM   3390 C CG  . GLU C 1 141 ? -22.83306 40.08938  -19.33744 1.000 40.02191 ? 141 GLU C CG  1 
ATOM   3391 C CD  . GLU C 1 141 ? -24.19497 40.19367  -19.95398 1.000 37.20212 ? 141 GLU C CD  1 
ATOM   3392 O OE1 . GLU C 1 141 ? -24.98376 41.06629  -19.54330 1.000 52.50872 ? 141 GLU C OE1 1 
ATOM   3393 O OE2 . GLU C 1 141 ? -24.48404 39.39071  -20.84729 1.000 42.59100 ? 141 GLU C OE2 1 
ATOM   3394 N N   . THR C 1 142 ? -21.98921 37.99272  -15.22749 1.000 40.10638 ? 142 THR C N   1 
ATOM   3395 C CA  . THR C 1 142 ? -21.70138 38.12713  -13.80805 1.000 36.95679 ? 142 THR C CA  1 
ATOM   3396 C C   . THR C 1 142 ? -20.23162 37.84694  -13.52109 1.000 44.48036 ? 142 THR C C   1 
ATOM   3397 O O   . THR C 1 142 ? -19.58059 38.60911  -12.80092 1.000 46.48963 ? 142 THR C O   1 
ATOM   3398 C CB  . THR C 1 142 ? -22.61154 37.21003  -13.00223 1.000 40.72693 ? 142 THR C CB  1 
ATOM   3399 O OG1 . THR C 1 142 ? -22.05232 35.89264  -12.94945 1.000 45.52763 ? 142 THR C OG1 1 
ATOM   3400 C CG2 . THR C 1 142 ? -23.98226 37.14523  -13.66363 1.000 44.33720 ? 142 THR C CG2 1 
ATOM   3401 N N   . ASN C 1 143 ? -19.67027 36.79642  -14.12162 1.000 43.83131 ? 143 ASN C N   1 
ATOM   3402 C CA  . ASN C 1 143 ? -18.30308 36.37678  -13.80515 1.000 43.27616 ? 143 ASN C CA  1 
ATOM   3403 C C   . ASN C 1 143 ? -17.24965 37.22858  -14.53353 1.000 44.35892 ? 143 ASN C C   1 
ATOM   3404 O O   . ASN C 1 143 ? -16.41977 36.73033  -15.29560 1.000 42.19191 ? 143 ASN C O   1 
ATOM   3405 C CB  . ASN C 1 143 ? -18.13235 34.89442  -14.12204 1.000 40.01388 ? 143 ASN C CB  1 
ATOM   3406 C CG  . ASN C 1 143 ? -18.64740 33.98605  -13.01232 1.000 41.55261 ? 143 ASN C CG  1 
ATOM   3407 O OD1 . ASN C 1 143 ? -18.36398 34.19997  -11.82551 1.000 38.67217 ? 143 ASN C OD1 1 
ATOM   3408 N ND2 . ASN C 1 143 ? -19.39838 32.95727  -13.39664 1.000 36.05120 ? 143 ASN C ND2 1 
ATOM   3409 N N   . VAL C 1 144 ? -17.27402 38.53665  -14.26678 1.000 40.68557 ? 144 VAL C N   1 
ATOM   3410 C CA  . VAL C 1 144 ? -16.27608 39.46790  -14.79456 1.000 48.11000 ? 144 VAL C CA  1 
ATOM   3411 C C   . VAL C 1 144 ? -15.88280 40.44621  -13.69226 1.000 44.53419 ? 144 VAL C C   1 
ATOM   3412 O O   . VAL C 1 144 ? -16.73229 40.89525  -12.91416 1.000 37.80567 ? 144 VAL C O   1 
ATOM   3413 C CB  . VAL C 1 144 ? -16.78868 40.23047  -16.04103 1.000 50.02111 ? 144 VAL C CB  1 
ATOM   3414 C CG1 . VAL C 1 144 ? -15.80770 41.31287  -16.46826 1.000 38.65583 ? 144 VAL C CG1 1 
ATOM   3415 C CG2 . VAL C 1 144 ? -17.01534 39.27384  -17.18637 1.000 45.70409 ? 144 VAL C CG2 1 
ATOM   3416 N N   . ASP C 1 145 ? -14.58983 40.76676  -13.61756 1.000 47.97040 ? 145 ASP C N   1 
ATOM   3417 C CA  . ASP C 1 145 ? -14.11587 41.78776  -12.68314 1.000 48.95405 ? 145 ASP C CA  1 
ATOM   3418 C C   . ASP C 1 145 ? -13.45716 42.93959  -13.42787 1.000 39.33912 ? 145 ASP C C   1 
ATOM   3419 O O   . ASP C 1 145 ? -13.68676 44.09960  -13.10235 1.000 41.68341 ? 145 ASP C O   1 
ATOM   3420 C CB  . ASP C 1 145 ? -13.13626 41.20135  -11.65764 1.000 39.37443 ? 145 ASP C CB  1 
ATOM   3421 C CG  . ASP C 1 145 ? -13.12073 41.99600  -10.35947 1.000 41.10244 ? 145 ASP C CG  1 
ATOM   3422 O OD1 . ASP C 1 145 ? -13.53192 43.18018  -10.39687 1.000 38.50429 ? 145 ASP C OD1 1 
ATOM   3423 O OD2 . ASP C 1 145 ? -12.71619 41.43958  -9.30893  1.000 26.18245 ? 145 ASP C OD2 1 
HETATM 3424 S S   . SO4 D 2 .   ? 11.13011  17.14467  -20.87444 1.000 27.54353 ? 201 SO4 A S   1 
HETATM 3425 O O1  . SO4 D 2 .   ? 12.52678  16.70164  -20.60398 1.000 28.12692 ? 201 SO4 A O1  1 
HETATM 3426 O O2  . SO4 D 2 .   ? 10.96408  17.24871  -22.35176 1.000 27.77621 ? 201 SO4 A O2  1 
HETATM 3427 O O3  . SO4 D 2 .   ? 10.16212  16.11928  -20.38191 1.000 28.23885 ? 201 SO4 A O3  1 
HETATM 3428 O O4  . SO4 D 2 .   ? 10.90369  18.45942  -20.20849 1.000 15.97124 ? 201 SO4 A O4  1 
HETATM 3429 S S   . SO4 E 2 .   ? -9.58660  6.40380   -25.09243 1.000 27.35983 ? 201 SO4 B S   1 
HETATM 3430 O O1  . SO4 E 2 .   ? -8.56885  5.80709   -24.16987 1.000 23.53613 ? 201 SO4 B O1  1 
HETATM 3431 O O2  . SO4 E 2 .   ? -10.70104 5.41624   -25.25627 1.000 25.65119 ? 201 SO4 B O2  1 
HETATM 3432 O O3  . SO4 E 2 .   ? -8.93351  6.74105   -26.39207 1.000 22.71518 ? 201 SO4 B O3  1 
HETATM 3433 O O4  . SO4 E 2 .   ? -10.13140 7.71338   -24.61348 1.000 22.25424 ? 201 SO4 B O4  1 
HETATM 3434 S S   . SO4 F 2 .   ? -8.07483  30.07313  -25.03950 1.000 35.33649 ? 201 SO4 C S   1 
HETATM 3435 O O1  . SO4 F 2 .   ? -7.44828  29.65569  -26.32987 1.000 33.73436 ? 201 SO4 C O1  1 
HETATM 3436 O O2  . SO4 F 2 .   ? -9.43327  29.46583  -24.84644 1.000 26.01227 ? 201 SO4 C O2  1 
HETATM 3437 O O3  . SO4 F 2 .   ? -7.20321  29.64510  -23.90107 1.000 32.50459 ? 201 SO4 C O3  1 
HETATM 3438 O O4  . SO4 F 2 .   ? -8.10065  31.56613  -25.05569 1.000 31.07525 ? 201 SO4 C O4  1 
HETATM 3439 O O   . HOH G 3 .   ? 8.73333   14.51516  -27.18043 1.000 22.80014 ? 301 HOH A O   1 
HETATM 3440 O O   . HOH G 3 .   ? 10.78833  6.04963   -34.15738 1.000 24.40129 ? 302 HOH A O   1 
HETATM 3441 O O   . HOH G 3 .   ? 8.45018   4.67477   3.71787   1.000 32.18834 ? 303 HOH A O   1 
HETATM 3442 O O   . HOH G 3 .   ? 21.25813  31.50653  -6.15430  1.000 27.65555 ? 304 HOH A O   1 
HETATM 3443 O O   . HOH G 3 .   ? 25.48868  30.03133  -16.98104 1.000 46.77712 ? 305 HOH A O   1 
HETATM 3444 O O   . HOH G 3 .   ? -18.98352 5.61436   -4.77911  1.000 36.68887 ? 306 HOH A O   1 
HETATM 3445 O O   . HOH G 3 .   ? -5.52646  -0.43819  -12.83029 1.000 15.17337 ? 307 HOH A O   1 
HETATM 3446 O O   . HOH G 3 .   ? 20.89219  17.69371  -21.02821 1.000 40.00367 ? 308 HOH A O   1 
HETATM 3447 O O   . HOH G 3 .   ? 17.88512  25.97921  -3.22756  1.000 22.32581 ? 309 HOH A O   1 
HETATM 3448 O O   . HOH G 3 .   ? -2.69619  5.78875   -4.94062  1.000 19.89231 ? 310 HOH A O   1 
HETATM 3449 O O   . HOH G 3 .   ? 0.69419   -2.46331  -3.20360  1.000 31.52345 ? 311 HOH A O   1 
HETATM 3450 O O   . HOH G 3 .   ? 29.54804  27.70503  -17.62244 1.000 45.80300 ? 312 HOH A O   1 
HETATM 3451 O O   . HOH G 3 .   ? 15.48998  4.90783   -13.45643 1.000 31.32376 ? 313 HOH A O   1 
HETATM 3452 O O   . HOH G 3 .   ? 8.51197   10.79609  -32.30223 1.000 24.72852 ? 314 HOH A O   1 
HETATM 3453 O O   . HOH G 3 .   ? 9.89432   -4.59498  -18.01548 1.000 23.65905 ? 315 HOH A O   1 
HETATM 3454 O O   . HOH G 3 .   ? 9.11934   24.73610  -29.19162 1.000 26.78321 ? 316 HOH A O   1 
HETATM 3455 O O   . HOH G 3 .   ? -4.52328  18.04386  -9.22651  1.000 26.20790 ? 317 HOH A O   1 
HETATM 3456 O O   . HOH G 3 .   ? 3.52348   -6.05406  -11.13206 1.000 20.11722 ? 318 HOH A O   1 
HETATM 3457 O O   . HOH G 3 .   ? 17.71761  17.49266  -23.45585 1.000 46.49247 ? 319 HOH A O   1 
HETATM 3458 O O   . HOH G 3 .   ? -7.41129  0.44295   -5.10671  1.000 30.65769 ? 320 HOH A O   1 
HETATM 3459 O O   . HOH G 3 .   ? 19.07149  8.99665   -13.81032 1.000 27.16254 ? 321 HOH A O   1 
HETATM 3460 O O   . HOH G 3 .   ? 16.58498  29.02577  -27.59011 1.000 32.15473 ? 322 HOH A O   1 
HETATM 3461 O O   . HOH G 3 .   ? 16.35772  35.90215  -14.25585 1.000 43.96277 ? 323 HOH A O   1 
HETATM 3462 O O   . HOH G 3 .   ? 11.18110  2.19650   -2.35399  1.000 26.27362 ? 324 HOH A O   1 
HETATM 3463 O O   . HOH G 3 .   ? 14.09347  4.81125   -6.42489  1.000 29.41547 ? 325 HOH A O   1 
HETATM 3464 O O   . HOH G 3 .   ? 9.25311   13.26277  -24.63837 1.000 13.78810 ? 326 HOH A O   1 
HETATM 3465 O O   . HOH G 3 .   ? 24.18915  20.92057  -25.65250 1.000 35.38574 ? 327 HOH A O   1 
HETATM 3466 O O   . HOH G 3 .   ? 12.41957  6.12917   6.44352   1.000 23.83121 ? 328 HOH A O   1 
HETATM 3467 O O   . HOH G 3 .   ? 2.600     18.978    -32.969   1.000 29.44314 ? 329 HOH A O   1 
HETATM 3468 O O   . HOH G 3 .   ? -10.92762 -2.01638  -2.45118  1.000 25.77936 ? 330 HOH A O   1 
HETATM 3469 O O   . HOH G 3 .   ? 15.15596  7.16533   5.55149   1.000 25.93567 ? 331 HOH A O   1 
HETATM 3470 O O   . HOH G 3 .   ? -11.06361 0.00000   0.00000   0.50  18.51687 ? 332 HOH A O   1 
HETATM 3471 O O   . HOH H 3 .   ? -24.47978 18.97337  -7.76264  1.000 31.92456 ? 301 HOH B O   1 
HETATM 3472 O O   . HOH H 3 .   ? 4.47363   8.16128   -29.18370 1.000 13.46584 ? 302 HOH B O   1 
HETATM 3473 O O   . HOH H 3 .   ? -27.69550 9.07278   -19.18980 1.000 31.40414 ? 303 HOH B O   1 
HETATM 3474 O O   . HOH H 3 .   ? -27.68855 19.03613  -5.17989  1.000 50.95444 ? 304 HOH B O   1 
HETATM 3475 O O   . HOH H 3 .   ? -24.66917 8.15544   -27.12969 1.000 46.73277 ? 305 HOH B O   1 
HETATM 3476 O O   . HOH H 3 .   ? -28.67570 21.90348  -17.00255 1.000 36.07116 ? 306 HOH B O   1 
HETATM 3477 O O   . HOH H 3 .   ? -14.17306 27.06406  -6.34017  1.000 31.94752 ? 307 HOH B O   1 
HETATM 3478 O O   . HOH H 3 .   ? -9.22786  10.64779  -30.66134 1.000 22.08002 ? 308 HOH B O   1 
HETATM 3479 O O   . HOH H 3 .   ? -16.54553 9.36947   -36.89016 1.000 19.32903 ? 309 HOH B O   1 
HETATM 3480 O O   . HOH H 3 .   ? -14.87306 17.66189  -31.55328 1.000 16.97329 ? 310 HOH B O   1 
HETATM 3481 O O   . HOH H 3 .   ? -3.67213  7.02923   -30.38633 1.000 21.09868 ? 311 HOH B O   1 
HETATM 3482 O O   . HOH H 3 .   ? -9.33019  14.18100  -35.45366 1.000 19.72865 ? 312 HOH B O   1 
HETATM 3483 O O   . HOH H 3 .   ? -19.10051 15.23640  -39.40142 1.000 31.33913 ? 313 HOH B O   1 
HETATM 3484 O O   . HOH H 3 .   ? -18.08183 21.24224  -7.79932  1.000 32.25493 ? 314 HOH B O   1 
HETATM 3485 O O   . HOH H 3 .   ? -5.45989  18.68135  -22.91933 1.000 21.57475 ? 315 HOH B O   1 
HETATM 3486 O O   . HOH H 3 .   ? -15.132   15.177    -38.055   1.000 18.82965 ? 316 HOH B O   1 
HETATM 3487 O O   . HOH H 3 .   ? -26.75869 2.04859   -17.49577 1.000 40.14851 ? 317 HOH B O   1 
HETATM 3488 O O   . HOH H 3 .   ? -12.30951 7.02766   -19.52453 1.000 29.38885 ? 318 HOH B O   1 
HETATM 3489 O O   . HOH H 3 .   ? -14.19165 22.64484  -9.86780  1.000 21.97946 ? 319 HOH B O   1 
HETATM 3490 O O   . HOH H 3 .   ? -18.27067 31.81793  -3.88480  1.000 31.08571 ? 320 HOH B O   1 
HETATM 3491 O O   . HOH H 3 .   ? -13.47348 4.71602   -31.11782 1.000 27.40372 ? 321 HOH B O   1 
HETATM 3492 O O   . HOH H 3 .   ? 2.16453   0.57760   -32.49504 1.000 24.78268 ? 322 HOH B O   1 
HETATM 3493 O O   . HOH H 3 .   ? -20.04955 3.12090   -5.43306  1.000 32.00805 ? 323 HOH B O   1 
HETATM 3494 O O   . HOH I 3 .   ? -9.98357  32.36310  -26.39964 1.000 36.72873 ? 301 HOH C O   1 
HETATM 3495 O O   . HOH I 3 .   ? -2.41287  28.09205  -29.61989 1.000 16.27121 ? 302 HOH C O   1 
HETATM 3496 O O   . HOH I 3 .   ? -2.29345  26.31072  -24.45132 1.000 27.27498 ? 303 HOH C O   1 
HETATM 3497 O O   . HOH I 3 .   ? -4.19884  19.31019  -33.55737 1.000 17.15242 ? 304 HOH C O   1 
HETATM 3498 O O   . HOH I 3 .   ? -1.16059  21.29252  -6.12538  1.000 18.45232 ? 305 HOH C O   1 
HETATM 3499 O O   . HOH I 3 .   ? -20.75594 42.24389  -29.96884 1.000 37.40022 ? 306 HOH C O   1 
HETATM 3500 O O   . HOH I 3 .   ? -9.06586  42.80063  -24.95210 1.000 31.61646 ? 307 HOH C O   1 
HETATM 3501 O O   . HOH I 3 .   ? 13.59066  33.93106  -8.87543  1.000 37.64021 ? 308 HOH C O   1 
HETATM 3502 O O   . HOH I 3 .   ? -7.02830  18.95014  -5.97276  1.000 34.91422 ? 309 HOH C O   1 
HETATM 3503 O O   . HOH I 3 .   ? 0.73468   41.21874  -4.85866  1.000 35.01085 ? 310 HOH C O   1 
HETATM 3504 O O   . HOH I 3 .   ? -11.88393 30.55485  -24.48094 1.000 29.82726 ? 311 HOH C O   1 
HETATM 3505 O O   . HOH I 3 .   ? -12.47448 37.08191  -33.58263 1.000 31.12033 ? 312 HOH C O   1 
HETATM 3506 O O   . HOH I 3 .   ? -24.14390 34.23579  -36.51648 1.000 62.60127 ? 313 HOH C O   1 
HETATM 3507 O O   . HOH I 3 .   ? 1.13673   36.74235  -33.65793 1.000 20.66711 ? 314 HOH C O   1 
HETATM 3508 O O   . HOH I 3 .   ? -14.74687 45.61918  -15.19567 1.000 42.19165 ? 315 HOH C O   1 
HETATM 3509 O O   . HOH I 3 .   ? -1.92763  26.30862  -32.10899 1.000 20.47547 ? 316 HOH C O   1 
HETATM 3510 O O   . HOH I 3 .   ? -0.84321  35.33352  -32.48668 1.000 28.50589 ? 317 HOH C O   1 
HETATM 3511 O O   . HOH I 3 .   ? 9.71208   25.21148  -1.81627  1.000 37.26820 ? 318 HOH C O   1 
HETATM 3512 O O   . HOH I 3 .   ? -10.75221 20.82298  -7.84240  1.000 24.13988 ? 319 HOH C O   1 
HETATM 3513 O O   . HOH I 3 .   ? -5.43632  22.14109  -23.53597 1.000 22.92380 ? 320 HOH C O   1 
HETATM 3514 O O   . HOH I 3 .   ? 0.63375   22.02860  3.52976   1.000 25.95694 ? 321 HOH C O   1 
HETATM 3515 O O   . HOH I 3 .   ? -16.26433 23.94805  -31.66962 1.000 36.87537 ? 322 HOH C O   1 
HETATM 3516 O O   . HOH I 3 .   ? -21.40868 40.51061  -11.26065 1.000 30.15698 ? 323 HOH C O   1 
HETATM 3517 O O   . HOH I 3 .   ? -23.14305 24.30534  -27.41915 1.000 32.48106 ? 324 HOH C O   1 
HETATM 3518 O O   . HOH I 3 .   ? 3.436     34.680    -37.020   1.000 23.49375 ? 325 HOH C O   1 
HETATM 3519 O O   . HOH I 3 .   ? -18.46603 23.31978  -32.95171 1.000 38.11284 ? 326 HOH C O   1 
# 
