data_9NF1
# 
_entry.id   9NF1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9NF1         pdb_00009nf1 10.2210/pdb9nf1/pdb 
WWPDB D_1000293259 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9NF1 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 geiger@chemistry.msu.edu James Geiger H 'principal investigator/group leader' 0000-0002-9443-4488 
3 draths@chemistry.msu.edu Karen Draths ? 'principal investigator/group leader' 0000-0001-7852-1090 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Silva, K.'    1 0000-0001-8539-1415 
'Geiger, J.H.' 2 0000-0002-9443-4488 
'Draths, K.'   3 0000-0001-7852-1090 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'cis-CaaD E114D apo' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Silva, K.'    1 ? 
primary 'Geiger, J.H.' 2 ? 
primary 'Draths, K.'   3 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cis-3-chloroacrylic acid dehalogenase' 18553.557 3   ? E114D ? ? 
2 non-polymer syn 'SULFATE ION'                           96.063    3   ? ?     ? ? 
3 water       nat water                                   18.015    555 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVDYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVDYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRTENLYFQGLEHH
HHHH
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PRO n 
1 2   VAL n 
1 3   TYR n 
1 4   MET n 
1 5   VAL n 
1 6   TYR n 
1 7   VAL n 
1 8   SER n 
1 9   GLN n 
1 10  ASP n 
1 11  ARG n 
1 12  LEU n 
1 13  THR n 
1 14  PRO n 
1 15  SER n 
1 16  ALA n 
1 17  LYS n 
1 18  HIS n 
1 19  ALA n 
1 20  VAL n 
1 21  ALA n 
1 22  LYS n 
1 23  ALA n 
1 24  ILE n 
1 25  THR n 
1 26  ASP n 
1 27  ALA n 
1 28  HIS n 
1 29  ARG n 
1 30  GLY n 
1 31  LEU n 
1 32  THR n 
1 33  GLY n 
1 34  THR n 
1 35  GLN n 
1 36  HIS n 
1 37  PHE n 
1 38  LEU n 
1 39  ALA n 
1 40  GLN n 
1 41  VAL n 
1 42  ASN n 
1 43  PHE n 
1 44  GLN n 
1 45  GLU n 
1 46  GLN n 
1 47  PRO n 
1 48  ALA n 
1 49  GLY n 
1 50  ASN n 
1 51  VAL n 
1 52  PHE n 
1 53  LEU n 
1 54  GLY n 
1 55  GLY n 
1 56  VAL n 
1 57  GLN n 
1 58  GLN n 
1 59  GLY n 
1 60  GLY n 
1 61  ASP n 
1 62  THR n 
1 63  ILE n 
1 64  PHE n 
1 65  VAL n 
1 66  HIS n 
1 67  GLY n 
1 68  LEU n 
1 69  HIS n 
1 70  ARG n 
1 71  GLU n 
1 72  GLY n 
1 73  ARG n 
1 74  SER n 
1 75  ALA n 
1 76  ASP n 
1 77  LEU n 
1 78  LYS n 
1 79  GLY n 
1 80  GLN n 
1 81  LEU n 
1 82  ALA n 
1 83  GLN n 
1 84  ARG n 
1 85  ILE n 
1 86  VAL n 
1 87  ASP n 
1 88  ASP n 
1 89  VAL n 
1 90  SER n 
1 91  VAL n 
1 92  ALA n 
1 93  ALA n 
1 94  GLU n 
1 95  ILE n 
1 96  ASP n 
1 97  ARG n 
1 98  LYS n 
1 99  HIS n 
1 100 ILE n 
1 101 TRP n 
1 102 VAL n 
1 103 TYR n 
1 104 PHE n 
1 105 GLY n 
1 106 GLU n 
1 107 MET n 
1 108 PRO n 
1 109 ALA n 
1 110 GLN n 
1 111 GLN n 
1 112 MET n 
1 113 VAL n 
1 114 ASP n 
1 115 TYR n 
1 116 GLY n 
1 117 ARG n 
1 118 PHE n 
1 119 LEU n 
1 120 PRO n 
1 121 GLN n 
1 122 PRO n 
1 123 GLY n 
1 124 HIS n 
1 125 GLU n 
1 126 GLY n 
1 127 GLU n 
1 128 TRP n 
1 129 PHE n 
1 130 ASP n 
1 131 ASN n 
1 132 LEU n 
1 133 SER n 
1 134 SER n 
1 135 ASP n 
1 136 GLU n 
1 137 ARG n 
1 138 ALA n 
1 139 PHE n 
1 140 MET n 
1 141 GLU n 
1 142 THR n 
1 143 ASN n 
1 144 VAL n 
1 145 ASP n 
1 146 VAL n 
1 147 SER n 
1 148 ARG n 
1 149 THR n 
1 150 GLU n 
1 151 ASN n 
1 152 LEU n 
1 153 TYR n 
1 154 PHE n 
1 155 GLN n 
1 156 GLY n 
1 157 LEU n 
1 158 GLU n 
1 159 HIS n 
1 160 HIS n 
1 161 HIS n 
1 162 HIS n 
1 163 HIS n 
1 164 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   164 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 cis-caaD 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'coryneform bacterium' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1728 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'   ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PRO 1   1   1   PRO PRO A . n 
A 1 2   VAL 2   2   2   VAL VAL A . n 
A 1 3   TYR 3   3   3   TYR TYR A . n 
A 1 4   MET 4   4   4   MET MET A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   TYR 6   6   6   TYR TYR A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   SER 8   8   8   SER SER A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  HIS 18  18  18  HIS HIS A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  LYS 22  22  22  LYS LYS A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ILE 24  24  24  ILE ILE A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  HIS 28  28  28  HIS HIS A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  GLY 30  30  30  GLY GLY A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  GLN 35  35  35  GLN GLN A . n 
A 1 36  HIS 36  36  36  HIS HIS A . n 
A 1 37  PHE 37  37  37  PHE PHE A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  GLN 40  40  40  GLN GLN A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  GLN 44  44  44  GLN GLN A . n 
A 1 45  GLU 45  45  45  GLU GLU A . n 
A 1 46  GLN 46  46  46  GLN GLN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ASN 50  50  50  ASN ASN A . n 
A 1 51  VAL 51  51  51  VAL VAL A . n 
A 1 52  PHE 52  52  52  PHE PHE A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  ASP 61  61  61  ASP ASP A . n 
A 1 62  THR 62  62  62  THR THR A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  PHE 64  64  64  PHE PHE A . n 
A 1 65  VAL 65  65  65  VAL VAL A . n 
A 1 66  HIS 66  66  66  HIS HIS A . n 
A 1 67  GLY 67  67  67  GLY GLY A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  HIS 69  69  69  HIS HIS A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  LEU 77  77  77  LEU LEU A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  GLN 80  80  80  GLN GLN A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  SER 90  90  90  SER SER A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  GLU 94  94  94  GLU GLU A . n 
A 1 95  ILE 95  95  95  ILE ILE A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  LYS 98  98  98  LYS LYS A . n 
A 1 99  HIS 99  99  99  HIS HIS A . n 
A 1 100 ILE 100 100 100 ILE ILE A . n 
A 1 101 TRP 101 101 101 TRP TRP A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 TYR 103 103 103 TYR TYR A . n 
A 1 104 PHE 104 104 104 PHE PHE A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 MET 107 107 107 MET MET A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 GLN 111 111 111 GLN GLN A . n 
A 1 112 MET 112 112 112 MET MET A . n 
A 1 113 VAL 113 113 113 VAL VAL A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 PHE 118 118 118 PHE PHE A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 PRO 120 120 120 PRO PRO A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 HIS 124 124 124 HIS HIS A . n 
A 1 125 GLU 125 125 125 GLU GLU A . n 
A 1 126 GLY 126 126 126 GLY GLY A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 TRP 128 128 128 TRP TRP A . n 
A 1 129 PHE 129 129 129 PHE PHE A . n 
A 1 130 ASP 130 130 130 ASP ASP A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 ARG 137 137 137 ARG ARG A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 MET 140 140 140 MET MET A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 THR 142 142 142 THR THR A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 VAL 144 144 144 VAL VAL A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 SER 147 147 ?   ?   ?   A . n 
A 1 148 ARG 148 148 ?   ?   ?   A . n 
A 1 149 THR 149 149 ?   ?   ?   A . n 
A 1 150 GLU 150 150 ?   ?   ?   A . n 
A 1 151 ASN 151 151 ?   ?   ?   A . n 
A 1 152 LEU 152 152 ?   ?   ?   A . n 
A 1 153 TYR 153 153 ?   ?   ?   A . n 
A 1 154 PHE 154 154 ?   ?   ?   A . n 
A 1 155 GLN 155 155 ?   ?   ?   A . n 
A 1 156 GLY 156 156 ?   ?   ?   A . n 
A 1 157 LEU 157 157 ?   ?   ?   A . n 
A 1 158 GLU 158 158 ?   ?   ?   A . n 
A 1 159 HIS 159 159 ?   ?   ?   A . n 
A 1 160 HIS 160 160 ?   ?   ?   A . n 
A 1 161 HIS 161 161 ?   ?   ?   A . n 
A 1 162 HIS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 HIS 164 164 ?   ?   ?   A . n 
B 1 1   PRO 1   1   1   PRO PRO B . n 
B 1 2   VAL 2   2   2   VAL VAL B . n 
B 1 3   TYR 3   3   3   TYR TYR B . n 
B 1 4   MET 4   4   4   MET MET B . n 
B 1 5   VAL 5   5   5   VAL VAL B . n 
B 1 6   TYR 6   6   6   TYR TYR B . n 
B 1 7   VAL 7   7   7   VAL VAL B . n 
B 1 8   SER 8   8   8   SER SER B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  ASP 10  10  10  ASP ASP B . n 
B 1 11  ARG 11  11  11  ARG ARG B . n 
B 1 12  LEU 12  12  12  LEU LEU B . n 
B 1 13  THR 13  13  13  THR THR B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  LYS 17  17  17  LYS LYS B . n 
B 1 18  HIS 18  18  18  HIS HIS B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  LYS 22  22  22  LYS LYS B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  ILE 24  24  24  ILE ILE B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  ASP 26  26  26  ASP ASP B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  HIS 28  28  28  HIS HIS B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  GLY 30  30  30  GLY GLY B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  GLY 33  33  33  GLY GLY B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  GLN 35  35  35  GLN GLN B . n 
B 1 36  HIS 36  36  36  HIS HIS B . n 
B 1 37  PHE 37  37  37  PHE PHE B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  GLN 40  40  40  GLN GLN B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  PHE 43  43  43  PHE PHE B . n 
B 1 44  GLN 44  44  44  GLN GLN B . n 
B 1 45  GLU 45  45  45  GLU GLU B . n 
B 1 46  GLN 46  46  46  GLN GLN B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  ALA 48  48  48  ALA ALA B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  ASN 50  50  50  ASN ASN B . n 
B 1 51  VAL 51  51  51  VAL VAL B . n 
B 1 52  PHE 52  52  52  PHE PHE B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  GLY 54  54  54  GLY GLY B . n 
B 1 55  GLY 55  55  55  GLY GLY B . n 
B 1 56  VAL 56  56  56  VAL VAL B . n 
B 1 57  GLN 57  57  57  GLN GLN B . n 
B 1 58  GLN 58  58  58  GLN GLN B . n 
B 1 59  GLY 59  59  59  GLY GLY B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  ASP 61  61  61  ASP ASP B . n 
B 1 62  THR 62  62  62  THR THR B . n 
B 1 63  ILE 63  63  63  ILE ILE B . n 
B 1 64  PHE 64  64  64  PHE PHE B . n 
B 1 65  VAL 65  65  65  VAL VAL B . n 
B 1 66  HIS 66  66  66  HIS HIS B . n 
B 1 67  GLY 67  67  67  GLY GLY B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  HIS 69  69  69  HIS HIS B . n 
B 1 70  ARG 70  70  70  ARG ARG B . n 
B 1 71  GLU 71  71  71  GLU GLU B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  ALA 75  75  75  ALA ALA B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  LEU 77  77  77  LEU LEU B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  GLN 80  80  80  GLN GLN B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ALA 82  82  82  ALA ALA B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ARG 84  84  84  ARG ARG B . n 
B 1 85  ILE 85  85  85  ILE ILE B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  SER 90  90  90  SER SER B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  ALA 93  93  93  ALA ALA B . n 
B 1 94  GLU 94  94  94  GLU GLU B . n 
B 1 95  ILE 95  95  95  ILE ILE B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  ARG 97  97  97  ARG ARG B . n 
B 1 98  LYS 98  98  98  LYS LYS B . n 
B 1 99  HIS 99  99  99  HIS HIS B . n 
B 1 100 ILE 100 100 100 ILE ILE B . n 
B 1 101 TRP 101 101 101 TRP TRP B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 TYR 103 103 103 TYR TYR B . n 
B 1 104 PHE 104 104 104 PHE PHE B . n 
B 1 105 GLY 105 105 105 GLY GLY B . n 
B 1 106 GLU 106 106 106 GLU GLU B . n 
B 1 107 MET 107 107 107 MET MET B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 GLN 111 111 111 GLN GLN B . n 
B 1 112 MET 112 112 112 MET MET B . n 
B 1 113 VAL 113 113 113 VAL VAL B . n 
B 1 114 ASP 114 114 114 ASP ASP B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 PHE 118 118 118 PHE PHE B . n 
B 1 119 LEU 119 119 119 LEU LEU B . n 
B 1 120 PRO 120 120 120 PRO PRO B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLY 123 123 123 GLY GLY B . n 
B 1 124 HIS 124 124 124 HIS HIS B . n 
B 1 125 GLU 125 125 125 GLU GLU B . n 
B 1 126 GLY 126 126 126 GLY GLY B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 TRP 128 128 128 TRP TRP B . n 
B 1 129 PHE 129 129 129 PHE PHE B . n 
B 1 130 ASP 130 130 130 ASP ASP B . n 
B 1 131 ASN 131 131 131 ASN ASN B . n 
B 1 132 LEU 132 132 132 LEU LEU B . n 
B 1 133 SER 133 133 133 SER SER B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 ARG 137 137 137 ARG ARG B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 MET 140 140 140 MET MET B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 THR 142 142 142 THR THR B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 VAL 144 144 144 VAL VAL B . n 
B 1 145 ASP 145 145 145 ASP ASP B . n 
B 1 146 VAL 146 146 146 VAL VAL B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 ARG 148 148 ?   ?   ?   B . n 
B 1 149 THR 149 149 ?   ?   ?   B . n 
B 1 150 GLU 150 150 ?   ?   ?   B . n 
B 1 151 ASN 151 151 ?   ?   ?   B . n 
B 1 152 LEU 152 152 ?   ?   ?   B . n 
B 1 153 TYR 153 153 ?   ?   ?   B . n 
B 1 154 PHE 154 154 ?   ?   ?   B . n 
B 1 155 GLN 155 155 ?   ?   ?   B . n 
B 1 156 GLY 156 156 ?   ?   ?   B . n 
B 1 157 LEU 157 157 ?   ?   ?   B . n 
B 1 158 GLU 158 158 ?   ?   ?   B . n 
B 1 159 HIS 159 159 ?   ?   ?   B . n 
B 1 160 HIS 160 160 ?   ?   ?   B . n 
B 1 161 HIS 161 161 ?   ?   ?   B . n 
B 1 162 HIS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 HIS 164 164 ?   ?   ?   B . n 
C 1 1   PRO 1   1   1   PRO PRO C . n 
C 1 2   VAL 2   2   2   VAL VAL C . n 
C 1 3   TYR 3   3   3   TYR TYR C . n 
C 1 4   MET 4   4   4   MET MET C . n 
C 1 5   VAL 5   5   5   VAL VAL C . n 
C 1 6   TYR 6   6   6   TYR TYR C . n 
C 1 7   VAL 7   7   7   VAL VAL C . n 
C 1 8   SER 8   8   8   SER SER C . n 
C 1 9   GLN 9   9   9   GLN GLN C . n 
C 1 10  ASP 10  10  10  ASP ASP C . n 
C 1 11  ARG 11  11  11  ARG ARG C . n 
C 1 12  LEU 12  12  12  LEU LEU C . n 
C 1 13  THR 13  13  13  THR THR C . n 
C 1 14  PRO 14  14  14  PRO PRO C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  LYS 17  17  17  LYS LYS C . n 
C 1 18  HIS 18  18  18  HIS HIS C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  VAL 20  20  20  VAL VAL C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  LYS 22  22  22  LYS LYS C . n 
C 1 23  ALA 23  23  23  ALA ALA C . n 
C 1 24  ILE 24  24  24  ILE ILE C . n 
C 1 25  THR 25  25  25  THR THR C . n 
C 1 26  ASP 26  26  26  ASP ASP C . n 
C 1 27  ALA 27  27  27  ALA ALA C . n 
C 1 28  HIS 28  28  28  HIS HIS C . n 
C 1 29  ARG 29  29  29  ARG ARG C . n 
C 1 30  GLY 30  30  30  GLY GLY C . n 
C 1 31  LEU 31  31  31  LEU LEU C . n 
C 1 32  THR 32  32  32  THR THR C . n 
C 1 33  GLY 33  33  33  GLY GLY C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  GLN 35  35  35  GLN GLN C . n 
C 1 36  HIS 36  36  36  HIS HIS C . n 
C 1 37  PHE 37  37  37  PHE PHE C . n 
C 1 38  LEU 38  38  38  LEU LEU C . n 
C 1 39  ALA 39  39  39  ALA ALA C . n 
C 1 40  GLN 40  40  40  GLN GLN C . n 
C 1 41  VAL 41  41  41  VAL VAL C . n 
C 1 42  ASN 42  42  42  ASN ASN C . n 
C 1 43  PHE 43  43  43  PHE PHE C . n 
C 1 44  GLN 44  44  44  GLN GLN C . n 
C 1 45  GLU 45  45  45  GLU GLU C . n 
C 1 46  GLN 46  46  46  GLN GLN C . n 
C 1 47  PRO 47  47  47  PRO PRO C . n 
C 1 48  ALA 48  48  48  ALA ALA C . n 
C 1 49  GLY 49  49  49  GLY GLY C . n 
C 1 50  ASN 50  50  50  ASN ASN C . n 
C 1 51  VAL 51  51  51  VAL VAL C . n 
C 1 52  PHE 52  52  52  PHE PHE C . n 
C 1 53  LEU 53  53  53  LEU LEU C . n 
C 1 54  GLY 54  54  54  GLY GLY C . n 
C 1 55  GLY 55  55  55  GLY GLY C . n 
C 1 56  VAL 56  56  56  VAL VAL C . n 
C 1 57  GLN 57  57  57  GLN GLN C . n 
C 1 58  GLN 58  58  58  GLN GLN C . n 
C 1 59  GLY 59  59  59  GLY GLY C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  ASP 61  61  61  ASP ASP C . n 
C 1 62  THR 62  62  62  THR THR C . n 
C 1 63  ILE 63  63  63  ILE ILE C . n 
C 1 64  PHE 64  64  64  PHE PHE C . n 
C 1 65  VAL 65  65  65  VAL VAL C . n 
C 1 66  HIS 66  66  66  HIS HIS C . n 
C 1 67  GLY 67  67  67  GLY GLY C . n 
C 1 68  LEU 68  68  68  LEU LEU C . n 
C 1 69  HIS 69  69  69  HIS HIS C . n 
C 1 70  ARG 70  70  70  ARG ARG C . n 
C 1 71  GLU 71  71  71  GLU GLU C . n 
C 1 72  GLY 72  72  72  GLY GLY C . n 
C 1 73  ARG 73  73  73  ARG ARG C . n 
C 1 74  SER 74  74  74  SER SER C . n 
C 1 75  ALA 75  75  75  ALA ALA C . n 
C 1 76  ASP 76  76  76  ASP ASP C . n 
C 1 77  LEU 77  77  77  LEU LEU C . n 
C 1 78  LYS 78  78  78  LYS LYS C . n 
C 1 79  GLY 79  79  79  GLY GLY C . n 
C 1 80  GLN 80  80  80  GLN GLN C . n 
C 1 81  LEU 81  81  81  LEU LEU C . n 
C 1 82  ALA 82  82  82  ALA ALA C . n 
C 1 83  GLN 83  83  83  GLN GLN C . n 
C 1 84  ARG 84  84  84  ARG ARG C . n 
C 1 85  ILE 85  85  85  ILE ILE C . n 
C 1 86  VAL 86  86  86  VAL VAL C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  ASP 88  88  88  ASP ASP C . n 
C 1 89  VAL 89  89  89  VAL VAL C . n 
C 1 90  SER 90  90  90  SER SER C . n 
C 1 91  VAL 91  91  91  VAL VAL C . n 
C 1 92  ALA 92  92  92  ALA ALA C . n 
C 1 93  ALA 93  93  93  ALA ALA C . n 
C 1 94  GLU 94  94  94  GLU GLU C . n 
C 1 95  ILE 95  95  95  ILE ILE C . n 
C 1 96  ASP 96  96  96  ASP ASP C . n 
C 1 97  ARG 97  97  97  ARG ARG C . n 
C 1 98  LYS 98  98  98  LYS LYS C . n 
C 1 99  HIS 99  99  99  HIS HIS C . n 
C 1 100 ILE 100 100 100 ILE ILE C . n 
C 1 101 TRP 101 101 101 TRP TRP C . n 
C 1 102 VAL 102 102 102 VAL VAL C . n 
C 1 103 TYR 103 103 103 TYR TYR C . n 
C 1 104 PHE 104 104 104 PHE PHE C . n 
C 1 105 GLY 105 105 105 GLY GLY C . n 
C 1 106 GLU 106 106 106 GLU GLU C . n 
C 1 107 MET 107 107 107 MET MET C . n 
C 1 108 PRO 108 108 108 PRO PRO C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 GLN 110 110 110 GLN GLN C . n 
C 1 111 GLN 111 111 111 GLN GLN C . n 
C 1 112 MET 112 112 112 MET MET C . n 
C 1 113 VAL 113 113 113 VAL VAL C . n 
C 1 114 ASP 114 114 114 ASP ASP C . n 
C 1 115 TYR 115 115 115 TYR TYR C . n 
C 1 116 GLY 116 116 116 GLY GLY C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 PHE 118 118 118 PHE PHE C . n 
C 1 119 LEU 119 119 119 LEU LEU C . n 
C 1 120 PRO 120 120 120 PRO PRO C . n 
C 1 121 GLN 121 121 121 GLN GLN C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLY 123 123 123 GLY GLY C . n 
C 1 124 HIS 124 124 124 HIS HIS C . n 
C 1 125 GLU 125 125 125 GLU GLU C . n 
C 1 126 GLY 126 126 126 GLY GLY C . n 
C 1 127 GLU 127 127 127 GLU GLU C . n 
C 1 128 TRP 128 128 128 TRP TRP C . n 
C 1 129 PHE 129 129 129 PHE PHE C . n 
C 1 130 ASP 130 130 130 ASP ASP C . n 
C 1 131 ASN 131 131 131 ASN ASN C . n 
C 1 132 LEU 132 132 132 LEU LEU C . n 
C 1 133 SER 133 133 133 SER SER C . n 
C 1 134 SER 134 134 134 SER SER C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 GLU 136 136 136 GLU GLU C . n 
C 1 137 ARG 137 137 137 ARG ARG C . n 
C 1 138 ALA 138 138 138 ALA ALA C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 MET 140 140 140 MET MET C . n 
C 1 141 GLU 141 141 141 GLU GLU C . n 
C 1 142 THR 142 142 142 THR THR C . n 
C 1 143 ASN 143 143 143 ASN ASN C . n 
C 1 144 VAL 144 144 144 VAL VAL C . n 
C 1 145 ASP 145 145 145 ASP ASP C . n 
C 1 146 VAL 146 146 146 VAL VAL C . n 
C 1 147 SER 147 147 ?   ?   ?   C . n 
C 1 148 ARG 148 148 ?   ?   ?   C . n 
C 1 149 THR 149 149 ?   ?   ?   C . n 
C 1 150 GLU 150 150 ?   ?   ?   C . n 
C 1 151 ASN 151 151 ?   ?   ?   C . n 
C 1 152 LEU 152 152 ?   ?   ?   C . n 
C 1 153 TYR 153 153 ?   ?   ?   C . n 
C 1 154 PHE 154 154 ?   ?   ?   C . n 
C 1 155 GLN 155 155 ?   ?   ?   C . n 
C 1 156 GLY 156 156 ?   ?   ?   C . n 
C 1 157 LEU 157 157 ?   ?   ?   C . n 
C 1 158 GLU 158 158 ?   ?   ?   C . n 
C 1 159 HIS 159 159 ?   ?   ?   C . n 
C 1 160 HIS 160 160 ?   ?   ?   C . n 
C 1 161 HIS 161 161 ?   ?   ?   C . n 
C 1 162 HIS 162 162 ?   ?   ?   C . n 
C 1 163 HIS 163 163 ?   ?   ?   C . n 
C 1 164 HIS 164 164 ?   ?   ?   C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 SO4 1   201 4   SO4 SO4 A . 
E 2 SO4 1   201 1   SO4 SO4 B . 
F 2 SO4 1   201 3   SO4 SO4 C . 
G 3 HOH 1   301 179 HOH HOH A . 
G 3 HOH 2   302 513 HOH HOH A . 
G 3 HOH 3   303 137 HOH HOH A . 
G 3 HOH 4   304 407 HOH HOH A . 
G 3 HOH 5   305 215 HOH HOH A . 
G 3 HOH 6   306 191 HOH HOH A . 
G 3 HOH 7   307 357 HOH HOH A . 
G 3 HOH 8   308 197 HOH HOH A . 
G 3 HOH 9   309 508 HOH HOH A . 
G 3 HOH 10  310 49  HOH HOH A . 
G 3 HOH 11  311 194 HOH HOH A . 
G 3 HOH 12  312 267 HOH HOH A . 
G 3 HOH 13  313 222 HOH HOH A . 
G 3 HOH 14  314 371 HOH HOH A . 
G 3 HOH 15  315 216 HOH HOH A . 
G 3 HOH 16  316 94  HOH HOH A . 
G 3 HOH 17  317 441 HOH HOH A . 
G 3 HOH 18  318 157 HOH HOH A . 
G 3 HOH 19  319 494 HOH HOH A . 
G 3 HOH 20  320 68  HOH HOH A . 
G 3 HOH 21  321 411 HOH HOH A . 
G 3 HOH 22  322 477 HOH HOH A . 
G 3 HOH 23  323 256 HOH HOH A . 
G 3 HOH 24  324 190 HOH HOH A . 
G 3 HOH 25  325 365 HOH HOH A . 
G 3 HOH 26  326 238 HOH HOH A . 
G 3 HOH 27  327 1   HOH HOH A . 
G 3 HOH 28  328 205 HOH HOH A . 
G 3 HOH 29  329 22  HOH HOH A . 
G 3 HOH 30  330 156 HOH HOH A . 
G 3 HOH 31  331 185 HOH HOH A . 
G 3 HOH 32  332 230 HOH HOH A . 
G 3 HOH 33  333 25  HOH HOH A . 
G 3 HOH 34  334 168 HOH HOH A . 
G 3 HOH 35  335 426 HOH HOH A . 
G 3 HOH 36  336 96  HOH HOH A . 
G 3 HOH 37  337 166 HOH HOH A . 
G 3 HOH 38  338 293 HOH HOH A . 
G 3 HOH 39  339 152 HOH HOH A . 
G 3 HOH 40  340 115 HOH HOH A . 
G 3 HOH 41  341 84  HOH HOH A . 
G 3 HOH 42  342 33  HOH HOH A . 
G 3 HOH 43  343 400 HOH HOH A . 
G 3 HOH 44  344 158 HOH HOH A . 
G 3 HOH 45  345 180 HOH HOH A . 
G 3 HOH 46  346 284 HOH HOH A . 
G 3 HOH 47  347 178 HOH HOH A . 
G 3 HOH 48  348 87  HOH HOH A . 
G 3 HOH 49  349 76  HOH HOH A . 
G 3 HOH 50  350 46  HOH HOH A . 
G 3 HOH 51  351 26  HOH HOH A . 
G 3 HOH 52  352 257 HOH HOH A . 
G 3 HOH 53  353 359 HOH HOH A . 
G 3 HOH 54  354 273 HOH HOH A . 
G 3 HOH 55  355 366 HOH HOH A . 
G 3 HOH 56  356 27  HOH HOH A . 
G 3 HOH 57  357 37  HOH HOH A . 
G 3 HOH 58  358 207 HOH HOH A . 
G 3 HOH 59  359 349 HOH HOH A . 
G 3 HOH 60  360 274 HOH HOH A . 
G 3 HOH 61  361 47  HOH HOH A . 
G 3 HOH 62  362 206 HOH HOH A . 
G 3 HOH 63  363 186 HOH HOH A . 
G 3 HOH 64  364 422 HOH HOH A . 
G 3 HOH 65  365 82  HOH HOH A . 
G 3 HOH 66  366 245 HOH HOH A . 
G 3 HOH 67  367 150 HOH HOH A . 
G 3 HOH 68  368 275 HOH HOH A . 
G 3 HOH 69  369 32  HOH HOH A . 
G 3 HOH 70  370 266 HOH HOH A . 
G 3 HOH 71  371 504 HOH HOH A . 
G 3 HOH 72  372 102 HOH HOH A . 
G 3 HOH 73  373 259 HOH HOH A . 
G 3 HOH 74  374 287 HOH HOH A . 
G 3 HOH 75  375 280 HOH HOH A . 
G 3 HOH 76  376 381 HOH HOH A . 
G 3 HOH 77  377 523 HOH HOH A . 
G 3 HOH 78  378 362 HOH HOH A . 
G 3 HOH 79  379 81  HOH HOH A . 
G 3 HOH 80  380 15  HOH HOH A . 
G 3 HOH 81  381 20  HOH HOH A . 
G 3 HOH 82  382 319 HOH HOH A . 
G 3 HOH 83  383 240 HOH HOH A . 
G 3 HOH 84  384 99  HOH HOH A . 
G 3 HOH 85  385 332 HOH HOH A . 
G 3 HOH 86  386 121 HOH HOH A . 
G 3 HOH 87  387 72  HOH HOH A . 
G 3 HOH 88  388 262 HOH HOH A . 
G 3 HOH 89  389 531 HOH HOH A . 
G 3 HOH 90  390 79  HOH HOH A . 
G 3 HOH 91  391 493 HOH HOH A . 
G 3 HOH 92  392 13  HOH HOH A . 
G 3 HOH 93  393 372 HOH HOH A . 
G 3 HOH 94  394 42  HOH HOH A . 
G 3 HOH 95  395 459 HOH HOH A . 
G 3 HOH 96  396 67  HOH HOH A . 
G 3 HOH 97  397 113 HOH HOH A . 
G 3 HOH 98  398 290 HOH HOH A . 
G 3 HOH 99  399 250 HOH HOH A . 
G 3 HOH 100 400 208 HOH HOH A . 
G 3 HOH 101 401 133 HOH HOH A . 
G 3 HOH 102 402 201 HOH HOH A . 
G 3 HOH 103 403 221 HOH HOH A . 
G 3 HOH 104 404 514 HOH HOH A . 
G 3 HOH 105 405 460 HOH HOH A . 
G 3 HOH 106 406 220 HOH HOH A . 
G 3 HOH 107 407 484 HOH HOH A . 
G 3 HOH 108 408 271 HOH HOH A . 
G 3 HOH 109 409 547 HOH HOH A . 
G 3 HOH 110 410 59  HOH HOH A . 
G 3 HOH 111 411 530 HOH HOH A . 
G 3 HOH 112 412 98  HOH HOH A . 
G 3 HOH 113 413 435 HOH HOH A . 
G 3 HOH 114 414 264 HOH HOH A . 
G 3 HOH 115 415 541 HOH HOH A . 
G 3 HOH 116 416 429 HOH HOH A . 
G 3 HOH 117 417 439 HOH HOH A . 
G 3 HOH 118 418 288 HOH HOH A . 
G 3 HOH 119 419 354 HOH HOH A . 
G 3 HOH 120 420 546 HOH HOH A . 
G 3 HOH 121 421 336 HOH HOH A . 
G 3 HOH 122 422 436 HOH HOH A . 
G 3 HOH 123 423 131 HOH HOH A . 
G 3 HOH 124 424 524 HOH HOH A . 
G 3 HOH 125 425 325 HOH HOH A . 
G 3 HOH 126 426 552 HOH HOH A . 
G 3 HOH 127 427 305 HOH HOH A . 
G 3 HOH 128 428 473 HOH HOH A . 
G 3 HOH 129 429 368 HOH HOH A . 
G 3 HOH 130 430 227 HOH HOH A . 
G 3 HOH 131 431 341 HOH HOH A . 
G 3 HOH 132 432 316 HOH HOH A . 
G 3 HOH 133 433 496 HOH HOH A . 
G 3 HOH 134 434 480 HOH HOH A . 
G 3 HOH 135 435 228 HOH HOH A . 
G 3 HOH 136 436 177 HOH HOH A . 
G 3 HOH 137 437 446 HOH HOH A . 
G 3 HOH 138 438 89  HOH HOH A . 
G 3 HOH 139 439 289 HOH HOH A . 
G 3 HOH 140 440 391 HOH HOH A . 
G 3 HOH 141 441 431 HOH HOH A . 
G 3 HOH 142 442 379 HOH HOH A . 
G 3 HOH 143 443 452 HOH HOH A . 
G 3 HOH 144 444 383 HOH HOH A . 
G 3 HOH 145 445 505 HOH HOH A . 
G 3 HOH 146 446 424 HOH HOH A . 
G 3 HOH 147 447 456 HOH HOH A . 
G 3 HOH 148 448 367 HOH HOH A . 
G 3 HOH 149 449 430 HOH HOH A . 
G 3 HOH 150 450 491 HOH HOH A . 
G 3 HOH 151 451 495 HOH HOH A . 
G 3 HOH 152 452 109 HOH HOH A . 
G 3 HOH 153 453 478 HOH HOH A . 
G 3 HOH 154 454 276 HOH HOH A . 
G 3 HOH 155 455 260 HOH HOH A . 
G 3 HOH 156 456 509 HOH HOH A . 
G 3 HOH 157 457 165 HOH HOH A . 
G 3 HOH 158 458 183 HOH HOH A . 
G 3 HOH 159 459 526 HOH HOH A . 
G 3 HOH 160 460 488 HOH HOH A . 
G 3 HOH 161 461 522 HOH HOH A . 
G 3 HOH 162 462 450 HOH HOH A . 
G 3 HOH 163 463 553 HOH HOH A . 
G 3 HOH 164 464 298 HOH HOH A . 
G 3 HOH 165 465 393 HOH HOH A . 
G 3 HOH 166 466 395 HOH HOH A . 
G 3 HOH 167 467 448 HOH HOH A . 
H 3 HOH 1   301 545 HOH HOH B . 
H 3 HOH 2   302 520 HOH HOH B . 
H 3 HOH 3   303 320 HOH HOH B . 
H 3 HOH 4   304 527 HOH HOH B . 
H 3 HOH 5   305 282 HOH HOH B . 
H 3 HOH 6   306 380 HOH HOH B . 
H 3 HOH 7   307 304 HOH HOH B . 
H 3 HOH 8   308 144 HOH HOH B . 
H 3 HOH 9   309 83  HOH HOH B . 
H 3 HOH 10  310 529 HOH HOH B . 
H 3 HOH 11  311 218 HOH HOH B . 
H 3 HOH 12  312 443 HOH HOH B . 
H 3 HOH 13  313 126 HOH HOH B . 
H 3 HOH 14  314 281 HOH HOH B . 
H 3 HOH 15  315 432 HOH HOH B . 
H 3 HOH 16  316 255 HOH HOH B . 
H 3 HOH 17  317 539 HOH HOH B . 
H 3 HOH 18  318 181 HOH HOH B . 
H 3 HOH 19  319 69  HOH HOH B . 
H 3 HOH 20  320 427 HOH HOH B . 
H 3 HOH 21  321 2   HOH HOH B . 
H 3 HOH 22  322 151 HOH HOH B . 
H 3 HOH 23  323 159 HOH HOH B . 
H 3 HOH 24  324 410 HOH HOH B . 
H 3 HOH 25  325 461 HOH HOH B . 
H 3 HOH 26  326 8   HOH HOH B . 
H 3 HOH 27  327 232 HOH HOH B . 
H 3 HOH 28  328 385 HOH HOH B . 
H 3 HOH 29  329 123 HOH HOH B . 
H 3 HOH 30  330 6   HOH HOH B . 
H 3 HOH 31  331 57  HOH HOH B . 
H 3 HOH 32  332 225 HOH HOH B . 
H 3 HOH 33  333 455 HOH HOH B . 
H 3 HOH 34  334 142 HOH HOH B . 
H 3 HOH 35  335 348 HOH HOH B . 
H 3 HOH 36  336 517 HOH HOH B . 
H 3 HOH 37  337 278 HOH HOH B . 
H 3 HOH 38  338 261 HOH HOH B . 
H 3 HOH 39  339 406 HOH HOH B . 
H 3 HOH 40  340 404 HOH HOH B . 
H 3 HOH 41  341 140 HOH HOH B . 
H 3 HOH 42  342 41  HOH HOH B . 
H 3 HOH 43  343 92  HOH HOH B . 
H 3 HOH 44  344 70  HOH HOH B . 
H 3 HOH 45  345 554 HOH HOH B . 
H 3 HOH 46  346 7   HOH HOH B . 
H 3 HOH 47  347 4   HOH HOH B . 
H 3 HOH 48  348 263 HOH HOH B . 
H 3 HOH 49  349 54  HOH HOH B . 
H 3 HOH 50  350 164 HOH HOH B . 
H 3 HOH 51  351 73  HOH HOH B . 
H 3 HOH 52  352 425 HOH HOH B . 
H 3 HOH 53  353 28  HOH HOH B . 
H 3 HOH 54  354 314 HOH HOH B . 
H 3 HOH 55  355 61  HOH HOH B . 
H 3 HOH 56  356 184 HOH HOH B . 
H 3 HOH 57  357 210 HOH HOH B . 
H 3 HOH 58  358 52  HOH HOH B . 
H 3 HOH 59  359 129 HOH HOH B . 
H 3 HOH 60  360 506 HOH HOH B . 
H 3 HOH 61  361 64  HOH HOH B . 
H 3 HOH 62  362 420 HOH HOH B . 
H 3 HOH 63  363 405 HOH HOH B . 
H 3 HOH 64  364 77  HOH HOH B . 
H 3 HOH 65  365 51  HOH HOH B . 
H 3 HOH 66  366 45  HOH HOH B . 
H 3 HOH 67  367 130 HOH HOH B . 
H 3 HOH 68  368 199 HOH HOH B . 
H 3 HOH 69  369 416 HOH HOH B . 
H 3 HOH 70  370 124 HOH HOH B . 
H 3 HOH 71  371 148 HOH HOH B . 
H 3 HOH 72  372 34  HOH HOH B . 
H 3 HOH 73  373 466 HOH HOH B . 
H 3 HOH 74  374 60  HOH HOH B . 
H 3 HOH 75  375 175 HOH HOH B . 
H 3 HOH 76  376 292 HOH HOH B . 
H 3 HOH 77  377 139 HOH HOH B . 
H 3 HOH 78  378 390 HOH HOH B . 
H 3 HOH 79  379 521 HOH HOH B . 
H 3 HOH 80  380 127 HOH HOH B . 
H 3 HOH 81  381 39  HOH HOH B . 
H 3 HOH 82  382 438 HOH HOH B . 
H 3 HOH 83  383 114 HOH HOH B . 
H 3 HOH 84  384 302 HOH HOH B . 
H 3 HOH 85  385 363 HOH HOH B . 
H 3 HOH 86  386 85  HOH HOH B . 
H 3 HOH 87  387 29  HOH HOH B . 
H 3 HOH 88  388 408 HOH HOH B . 
H 3 HOH 89  389 19  HOH HOH B . 
H 3 HOH 90  390 189 HOH HOH B . 
H 3 HOH 91  391 301 HOH HOH B . 
H 3 HOH 92  392 223 HOH HOH B . 
H 3 HOH 93  393 318 HOH HOH B . 
H 3 HOH 94  394 149 HOH HOH B . 
H 3 HOH 95  395 403 HOH HOH B . 
H 3 HOH 96  396 75  HOH HOH B . 
H 3 HOH 97  397 217 HOH HOH B . 
H 3 HOH 98  398 315 HOH HOH B . 
H 3 HOH 99  399 192 HOH HOH B . 
H 3 HOH 100 400 437 HOH HOH B . 
H 3 HOH 101 401 80  HOH HOH B . 
H 3 HOH 102 402 55  HOH HOH B . 
H 3 HOH 103 403 453 HOH HOH B . 
H 3 HOH 104 404 111 HOH HOH B . 
H 3 HOH 105 405 21  HOH HOH B . 
H 3 HOH 106 406 258 HOH HOH B . 
H 3 HOH 107 407 458 HOH HOH B . 
H 3 HOH 108 408 270 HOH HOH B . 
H 3 HOH 109 409 118 HOH HOH B . 
H 3 HOH 110 410 483 HOH HOH B . 
H 3 HOH 111 411 162 HOH HOH B . 
H 3 HOH 112 412 307 HOH HOH B . 
H 3 HOH 113 413 23  HOH HOH B . 
H 3 HOH 114 414 445 HOH HOH B . 
H 3 HOH 115 415 389 HOH HOH B . 
H 3 HOH 116 416 294 HOH HOH B . 
H 3 HOH 117 417 107 HOH HOH B . 
H 3 HOH 118 418 413 HOH HOH B . 
H 3 HOH 119 419 188 HOH HOH B . 
H 3 HOH 120 420 414 HOH HOH B . 
H 3 HOH 121 421 110 HOH HOH B . 
H 3 HOH 122 422 265 HOH HOH B . 
H 3 HOH 123 423 303 HOH HOH B . 
H 3 HOH 124 424 487 HOH HOH B . 
H 3 HOH 125 425 502 HOH HOH B . 
H 3 HOH 126 426 286 HOH HOH B . 
H 3 HOH 127 427 74  HOH HOH B . 
H 3 HOH 128 428 507 HOH HOH B . 
H 3 HOH 129 429 409 HOH HOH B . 
H 3 HOH 130 430 433 HOH HOH B . 
H 3 HOH 131 431 226 HOH HOH B . 
H 3 HOH 132 432 44  HOH HOH B . 
H 3 HOH 133 433 551 HOH HOH B . 
H 3 HOH 134 434 510 HOH HOH B . 
H 3 HOH 135 435 329 HOH HOH B . 
H 3 HOH 136 436 485 HOH HOH B . 
H 3 HOH 137 437 532 HOH HOH B . 
H 3 HOH 138 438 398 HOH HOH B . 
H 3 HOH 139 439 310 HOH HOH B . 
H 3 HOH 140 440 364 HOH HOH B . 
H 3 HOH 141 441 540 HOH HOH B . 
H 3 HOH 142 442 246 HOH HOH B . 
H 3 HOH 143 443 212 HOH HOH B . 
H 3 HOH 144 444 105 HOH HOH B . 
H 3 HOH 145 445 525 HOH HOH B . 
H 3 HOH 146 446 548 HOH HOH B . 
H 3 HOH 147 447 295 HOH HOH B . 
H 3 HOH 148 448 498 HOH HOH B . 
H 3 HOH 149 449 31  HOH HOH B . 
H 3 HOH 150 450 555 HOH HOH B . 
H 3 HOH 151 451 538 HOH HOH B . 
H 3 HOH 152 452 331 HOH HOH B . 
H 3 HOH 153 453 299 HOH HOH B . 
H 3 HOH 154 454 100 HOH HOH B . 
H 3 HOH 155 455 512 HOH HOH B . 
H 3 HOH 156 456 474 HOH HOH B . 
H 3 HOH 157 457 154 HOH HOH B . 
H 3 HOH 158 458 169 HOH HOH B . 
H 3 HOH 159 459 418 HOH HOH B . 
H 3 HOH 160 460 344 HOH HOH B . 
H 3 HOH 161 461 536 HOH HOH B . 
H 3 HOH 162 462 195 HOH HOH B . 
H 3 HOH 163 463 440 HOH HOH B . 
H 3 HOH 164 464 415 HOH HOH B . 
H 3 HOH 165 465 515 HOH HOH B . 
H 3 HOH 166 466 313 HOH HOH B . 
H 3 HOH 167 467 396 HOH HOH B . 
H 3 HOH 168 468 387 HOH HOH B . 
H 3 HOH 169 469 447 HOH HOH B . 
H 3 HOH 170 470 399 HOH HOH B . 
H 3 HOH 171 471 388 HOH HOH B . 
H 3 HOH 172 472 236 HOH HOH B . 
H 3 HOH 173 473 476 HOH HOH B . 
H 3 HOH 174 474 355 HOH HOH B . 
H 3 HOH 175 475 291 HOH HOH B . 
H 3 HOH 176 476 343 HOH HOH B . 
H 3 HOH 177 477 463 HOH HOH B . 
H 3 HOH 178 478 376 HOH HOH B . 
H 3 HOH 179 479 481 HOH HOH B . 
H 3 HOH 180 480 351 HOH HOH B . 
H 3 HOH 181 481 501 HOH HOH B . 
H 3 HOH 182 482 374 HOH HOH B . 
H 3 HOH 183 483 269 HOH HOH B . 
H 3 HOH 184 484 171 HOH HOH B . 
H 3 HOH 185 485 202 HOH HOH B . 
H 3 HOH 186 486 467 HOH HOH B . 
H 3 HOH 187 487 373 HOH HOH B . 
H 3 HOH 188 488 90  HOH HOH B . 
H 3 HOH 189 489 464 HOH HOH B . 
H 3 HOH 190 490 370 HOH HOH B . 
H 3 HOH 191 491 544 HOH HOH B . 
H 3 HOH 192 492 497 HOH HOH B . 
H 3 HOH 193 493 472 HOH HOH B . 
H 3 HOH 194 494 468 HOH HOH B . 
H 3 HOH 195 495 465 HOH HOH B . 
H 3 HOH 196 496 490 HOH HOH B . 
I 3 HOH 1   301 550 HOH HOH C . 
I 3 HOH 2   302 482 HOH HOH C . 
I 3 HOH 3   303 268 HOH HOH C . 
I 3 HOH 4   304 534 HOH HOH C . 
I 3 HOH 5   305 279 HOH HOH C . 
I 3 HOH 6   306 470 HOH HOH C . 
I 3 HOH 7   307 116 HOH HOH C . 
I 3 HOH 8   308 338 HOH HOH C . 
I 3 HOH 9   309 173 HOH HOH C . 
I 3 HOH 10  310 143 HOH HOH C . 
I 3 HOH 11  311 486 HOH HOH C . 
I 3 HOH 12  312 119 HOH HOH C . 
I 3 HOH 13  313 469 HOH HOH C . 
I 3 HOH 14  314 233 HOH HOH C . 
I 3 HOH 15  315 311 HOH HOH C . 
I 3 HOH 16  316 17  HOH HOH C . 
I 3 HOH 17  317 120 HOH HOH C . 
I 3 HOH 18  318 306 HOH HOH C . 
I 3 HOH 19  319 198 HOH HOH C . 
I 3 HOH 20  320 95  HOH HOH C . 
I 3 HOH 21  321 239 HOH HOH C . 
I 3 HOH 22  322 444 HOH HOH C . 
I 3 HOH 23  323 204 HOH HOH C . 
I 3 HOH 24  324 549 HOH HOH C . 
I 3 HOH 25  325 283 HOH HOH C . 
I 3 HOH 26  326 117 HOH HOH C . 
I 3 HOH 27  327 5   HOH HOH C . 
I 3 HOH 28  328 161 HOH HOH C . 
I 3 HOH 29  329 101 HOH HOH C . 
I 3 HOH 30  330 3   HOH HOH C . 
I 3 HOH 31  331 312 HOH HOH C . 
I 3 HOH 32  332 434 HOH HOH C . 
I 3 HOH 33  333 397 HOH HOH C . 
I 3 HOH 34  334 449 HOH HOH C . 
I 3 HOH 35  335 203 HOH HOH C . 
I 3 HOH 36  336 53  HOH HOH C . 
I 3 HOH 37  337 174 HOH HOH C . 
I 3 HOH 38  338 537 HOH HOH C . 
I 3 HOH 39  339 71  HOH HOH C . 
I 3 HOH 40  340 361 HOH HOH C . 
I 3 HOH 41  341 10  HOH HOH C . 
I 3 HOH 42  342 30  HOH HOH C . 
I 3 HOH 43  343 160 HOH HOH C . 
I 3 HOH 44  344 200 HOH HOH C . 
I 3 HOH 45  345 172 HOH HOH C . 
I 3 HOH 46  346 9   HOH HOH C . 
I 3 HOH 47  347 146 HOH HOH C . 
I 3 HOH 48  348 40  HOH HOH C . 
I 3 HOH 49  349 58  HOH HOH C . 
I 3 HOH 50  350 241 HOH HOH C . 
I 3 HOH 51  351 300 HOH HOH C . 
I 3 HOH 52  352 242 HOH HOH C . 
I 3 HOH 53  353 145 HOH HOH C . 
I 3 HOH 54  354 296 HOH HOH C . 
I 3 HOH 55  355 136 HOH HOH C . 
I 3 HOH 56  356 122 HOH HOH C . 
I 3 HOH 57  357 323 HOH HOH C . 
I 3 HOH 58  358 375 HOH HOH C . 
I 3 HOH 59  359 78  HOH HOH C . 
I 3 HOH 60  360 253 HOH HOH C . 
I 3 HOH 61  361 358 HOH HOH C . 
I 3 HOH 62  362 170 HOH HOH C . 
I 3 HOH 63  363 106 HOH HOH C . 
I 3 HOH 64  364 285 HOH HOH C . 
I 3 HOH 65  365 50  HOH HOH C . 
I 3 HOH 66  366 112 HOH HOH C . 
I 3 HOH 67  367 12  HOH HOH C . 
I 3 HOH 68  368 402 HOH HOH C . 
I 3 HOH 69  369 297 HOH HOH C . 
I 3 HOH 70  370 277 HOH HOH C . 
I 3 HOH 71  371 91  HOH HOH C . 
I 3 HOH 72  372 65  HOH HOH C . 
I 3 HOH 73  373 24  HOH HOH C . 
I 3 HOH 74  374 243 HOH HOH C . 
I 3 HOH 75  375 56  HOH HOH C . 
I 3 HOH 76  376 237 HOH HOH C . 
I 3 HOH 77  377 244 HOH HOH C . 
I 3 HOH 78  378 247 HOH HOH C . 
I 3 HOH 79  379 339 HOH HOH C . 
I 3 HOH 80  380 503 HOH HOH C . 
I 3 HOH 81  381 141 HOH HOH C . 
I 3 HOH 82  382 167 HOH HOH C . 
I 3 HOH 83  383 134 HOH HOH C . 
I 3 HOH 84  384 326 HOH HOH C . 
I 3 HOH 85  385 11  HOH HOH C . 
I 3 HOH 86  386 93  HOH HOH C . 
I 3 HOH 87  387 322 HOH HOH C . 
I 3 HOH 88  388 219 HOH HOH C . 
I 3 HOH 89  389 335 HOH HOH C . 
I 3 HOH 90  390 16  HOH HOH C . 
I 3 HOH 91  391 153 HOH HOH C . 
I 3 HOH 92  392 224 HOH HOH C . 
I 3 HOH 93  393 48  HOH HOH C . 
I 3 HOH 94  394 328 HOH HOH C . 
I 3 HOH 95  395 97  HOH HOH C . 
I 3 HOH 96  396 14  HOH HOH C . 
I 3 HOH 97  397 38  HOH HOH C . 
I 3 HOH 98  398 345 HOH HOH C . 
I 3 HOH 99  399 235 HOH HOH C . 
I 3 HOH 100 400 196 HOH HOH C . 
I 3 HOH 101 401 86  HOH HOH C . 
I 3 HOH 102 402 412 HOH HOH C . 
I 3 HOH 103 403 386 HOH HOH C . 
I 3 HOH 104 404 138 HOH HOH C . 
I 3 HOH 105 405 63  HOH HOH C . 
I 3 HOH 106 406 234 HOH HOH C . 
I 3 HOH 107 407 542 HOH HOH C . 
I 3 HOH 108 408 251 HOH HOH C . 
I 3 HOH 109 409 213 HOH HOH C . 
I 3 HOH 110 410 272 HOH HOH C . 
I 3 HOH 111 411 378 HOH HOH C . 
I 3 HOH 112 412 309 HOH HOH C . 
I 3 HOH 113 413 342 HOH HOH C . 
I 3 HOH 114 414 35  HOH HOH C . 
I 3 HOH 115 415 334 HOH HOH C . 
I 3 HOH 116 416 176 HOH HOH C . 
I 3 HOH 117 417 104 HOH HOH C . 
I 3 HOH 118 418 62  HOH HOH C . 
I 3 HOH 119 419 18  HOH HOH C . 
I 3 HOH 120 420 533 HOH HOH C . 
I 3 HOH 121 421 511 HOH HOH C . 
I 3 HOH 122 422 103 HOH HOH C . 
I 3 HOH 123 423 125 HOH HOH C . 
I 3 HOH 124 424 451 HOH HOH C . 
I 3 HOH 125 425 421 HOH HOH C . 
I 3 HOH 126 426 128 HOH HOH C . 
I 3 HOH 127 427 384 HOH HOH C . 
I 3 HOH 128 428 249 HOH HOH C . 
I 3 HOH 129 429 231 HOH HOH C . 
I 3 HOH 130 430 337 HOH HOH C . 
I 3 HOH 131 431 163 HOH HOH C . 
I 3 HOH 132 432 369 HOH HOH C . 
I 3 HOH 133 433 308 HOH HOH C . 
I 3 HOH 134 434 187 HOH HOH C . 
I 3 HOH 135 435 516 HOH HOH C . 
I 3 HOH 136 436 155 HOH HOH C . 
I 3 HOH 137 437 353 HOH HOH C . 
I 3 HOH 138 438 457 HOH HOH C . 
I 3 HOH 139 439 330 HOH HOH C . 
I 3 HOH 140 440 528 HOH HOH C . 
I 3 HOH 141 441 382 HOH HOH C . 
I 3 HOH 142 442 419 HOH HOH C . 
I 3 HOH 143 443 423 HOH HOH C . 
I 3 HOH 144 444 211 HOH HOH C . 
I 3 HOH 145 445 321 HOH HOH C . 
I 3 HOH 146 446 43  HOH HOH C . 
I 3 HOH 147 447 356 HOH HOH C . 
I 3 HOH 148 448 333 HOH HOH C . 
I 3 HOH 149 449 428 HOH HOH C . 
I 3 HOH 150 450 543 HOH HOH C . 
I 3 HOH 151 451 499 HOH HOH C . 
I 3 HOH 152 452 535 HOH HOH C . 
I 3 HOH 153 453 317 HOH HOH C . 
I 3 HOH 154 454 462 HOH HOH C . 
I 3 HOH 155 455 36  HOH HOH C . 
I 3 HOH 156 456 254 HOH HOH C . 
I 3 HOH 157 457 248 HOH HOH C . 
I 3 HOH 158 458 209 HOH HOH C . 
I 3 HOH 159 459 454 HOH HOH C . 
I 3 HOH 160 460 471 HOH HOH C . 
I 3 HOH 161 461 229 HOH HOH C . 
I 3 HOH 162 462 417 HOH HOH C . 
I 3 HOH 163 463 66  HOH HOH C . 
I 3 HOH 164 464 182 HOH HOH C . 
I 3 HOH 165 465 324 HOH HOH C . 
I 3 HOH 166 466 518 HOH HOH C . 
I 3 HOH 167 467 360 HOH HOH C . 
I 3 HOH 168 468 352 HOH HOH C . 
I 3 HOH 169 469 327 HOH HOH C . 
I 3 HOH 170 470 147 HOH HOH C . 
I 3 HOH 171 471 347 HOH HOH C . 
I 3 HOH 172 472 252 HOH HOH C . 
I 3 HOH 173 473 492 HOH HOH C . 
I 3 HOH 174 474 377 HOH HOH C . 
I 3 HOH 175 475 489 HOH HOH C . 
I 3 HOH 176 476 214 HOH HOH C . 
I 3 HOH 177 477 135 HOH HOH C . 
I 3 HOH 178 478 340 HOH HOH C . 
I 3 HOH 179 479 394 HOH HOH C . 
I 3 HOH 180 480 350 HOH HOH C . 
I 3 HOH 181 481 193 HOH HOH C . 
I 3 HOH 182 482 108 HOH HOH C . 
I 3 HOH 183 483 401 HOH HOH C . 
I 3 HOH 184 484 519 HOH HOH C . 
I 3 HOH 185 485 88  HOH HOH C . 
I 3 HOH 186 486 479 HOH HOH C . 
I 3 HOH 187 487 132 HOH HOH C . 
I 3 HOH 188 488 500 HOH HOH C . 
I 3 HOH 189 489 346 HOH HOH C . 
I 3 HOH 190 490 475 HOH HOH C . 
I 3 HOH 191 491 442 HOH HOH C . 
I 3 HOH 192 492 392 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9NF1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     59.997 
_cell.length_a_esd                 ? 
_cell.length_b                     100.294 
_cell.length_b_esd                 ? 
_cell.length_c                     147.226 
_cell.length_c_esd                 ? 
_cell.volume                       885908.769 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9NF1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9NF1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.99 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          38.18 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M ammonium sulfate 20% w/v PEG 3,351' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            296 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 S 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-09 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.13 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 21-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.13 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   21-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          14.23 
_reflns.entry_id                                       9NF1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.60 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     52366 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           88.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                7.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          26.63 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.023 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.60 
_reflns_shell.d_res_low                                     1.63 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2769 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.309 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               18.66 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9NF1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.60 
_refine.ls_d_res_low                             29.20 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     51846 
_refine.ls_number_reflns_R_free                  2002 
_refine.ls_number_reflns_R_work                  49844 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    88.14 
_refine.ls_percent_reflns_R_free                 3.86 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1777 
_refine.ls_R_factor_R_free                       0.2196 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1761 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.1762 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1657 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.60 
_refine_hist.d_res_low                        29.20 
_refine_hist.number_atoms_solvent             555 
_refine_hist.number_atoms_total               4020 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3450 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         15 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0071 ? 3553 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9700 ? 4816 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0620 ? 503  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0092 ? 645  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 6.1767 ? 474  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.correlation_coeff_Fo_to_Fc 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.60 1.64  . . 133 3384 85.05 . . . . 0.2420 . . . . . . . . . . . . . . . 0.3168 
'X-RAY DIFFRACTION' 1.64 1.68  . . 137 3625 89.89 . . . . 0.2170 . . . . . . . . . . . . . . . 0.2492 
'X-RAY DIFFRACTION' 1.68 1.73  . . 156 3923 98.84 . . . . 0.2044 . . . . . . . . . . . . . . . 0.2285 
'X-RAY DIFFRACTION' 1.73 1.79  . . 169 3997 99.74 . . . . 0.2034 . . . . . . . . . . . . . . . 0.2461 
'X-RAY DIFFRACTION' 1.79 1.85  . . 162 3981 99.69 . . . . 0.1890 . . . . . . . . . . . . . . . 0.2381 
'X-RAY DIFFRACTION' 1.85 1.93  . . 117 2767 68.83 . . . . 0.1919 . . . . . . . . . . . . . . . 0.2281 
'X-RAY DIFFRACTION' 1.93 2.02  . . 156 3776 94.20 . . . . 0.1805 . . . . . . . . . . . . . . . 0.2088 
'X-RAY DIFFRACTION' 2.02 2.12  . . 157 3946 99.18 . . . . 0.1756 . . . . . . . . . . . . . . . 0.2112 
'X-RAY DIFFRACTION' 2.12 2.25  . . 122 2967 75.60 . . . . 0.1806 . . . . . . . . . . . . . . . 0.2130 
'X-RAY DIFFRACTION' 2.28 2.43  . . 133 3243 92.24 . . . . 0.1751 . . . . . . . . . . . . . . . 0.2121 
'X-RAY DIFFRACTION' 2.43 2.67  . . 148 3771 93.44 . . . . 0.1754 . . . . . . . . . . . . . . . 0.2346 
'X-RAY DIFFRACTION' 2.67 3.06  . . 145 3502 85.83 . . . . 0.1784 . . . . . . . . . . . . . . . 0.2102 
'X-RAY DIFFRACTION' 3.06 3.85  . . 123 3179 77.38 . . . . 0.1587 . . . . . . . . . . . . . . . 0.2224 
'X-RAY DIFFRACTION' 3.86 29.20 . . 144 3783 88.91 . . . . 0.1524 . . . . . . . . . . . . . . . 0.1938 
# 
_struct.entry_id                     9NF1 
_struct.title                        'cis-CaaD E114D mutant' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9NF1 
_struct_keywords.text            'cis-CaaD, Tautomerase, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    Q6VPE5_9CORY 
_struct_ref.pdbx_db_accession          Q6VPE5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PVYMVYVSQDRLTPSAKHAVAKAITDAHRGLTGTQHFLAQVNFQEQPAGNVFLGGVQQGGDTIFVHGLHREGRSADLKGQ
LAQRIVDDVSVAAEIDRKHIWVYFGEMPAQQMVEYGRFLPQPGHEGEWFDNLSSDERAFMETNVDVSRT
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9NF1 A 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
2 1 9NF1 B 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
3 1 9NF1 C 1 ? 149 ? Q6VPE5 2 ? 150 ? 1 149 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9NF1 ASP A 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 1  
1 9NF1 GLU A 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 2  
1 9NF1 ASN A 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 3  
1 9NF1 LEU A 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 4  
1 9NF1 TYR A 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 5  
1 9NF1 PHE A 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 6  
1 9NF1 GLN A 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 7  
1 9NF1 GLY A 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 8  
1 9NF1 LEU A 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 9  
1 9NF1 GLU A 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 10 
1 9NF1 HIS A 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 11 
1 9NF1 HIS A 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 12 
1 9NF1 HIS A 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 13 
1 9NF1 HIS A 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 14 
1 9NF1 HIS A 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 15 
1 9NF1 HIS A 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 16 
2 9NF1 ASP B 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 17 
2 9NF1 GLU B 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 18 
2 9NF1 ASN B 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 19 
2 9NF1 LEU B 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 20 
2 9NF1 TYR B 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 21 
2 9NF1 PHE B 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 22 
2 9NF1 GLN B 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 23 
2 9NF1 GLY B 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 24 
2 9NF1 LEU B 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 25 
2 9NF1 GLU B 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 26 
2 9NF1 HIS B 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 27 
2 9NF1 HIS B 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 28 
2 9NF1 HIS B 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 29 
2 9NF1 HIS B 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 30 
2 9NF1 HIS B 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 31 
2 9NF1 HIS B 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 32 
3 9NF1 ASP C 114 ? UNP Q6VPE5 GLU 115 'engineered mutation' 114 33 
3 9NF1 GLU C 150 ? UNP Q6VPE5 ?   ?   'expression tag'      150 34 
3 9NF1 ASN C 151 ? UNP Q6VPE5 ?   ?   'expression tag'      151 35 
3 9NF1 LEU C 152 ? UNP Q6VPE5 ?   ?   'expression tag'      152 36 
3 9NF1 TYR C 153 ? UNP Q6VPE5 ?   ?   'expression tag'      153 37 
3 9NF1 PHE C 154 ? UNP Q6VPE5 ?   ?   'expression tag'      154 38 
3 9NF1 GLN C 155 ? UNP Q6VPE5 ?   ?   'expression tag'      155 39 
3 9NF1 GLY C 156 ? UNP Q6VPE5 ?   ?   'expression tag'      156 40 
3 9NF1 LEU C 157 ? UNP Q6VPE5 ?   ?   'expression tag'      157 41 
3 9NF1 GLU C 158 ? UNP Q6VPE5 ?   ?   'expression tag'      158 42 
3 9NF1 HIS C 159 ? UNP Q6VPE5 ?   ?   'expression tag'      159 43 
3 9NF1 HIS C 160 ? UNP Q6VPE5 ?   ?   'expression tag'      160 44 
3 9NF1 HIS C 161 ? UNP Q6VPE5 ?   ?   'expression tag'      161 45 
3 9NF1 HIS C 162 ? UNP Q6VPE5 ?   ?   'expression tag'      162 46 
3 9NF1 HIS C 163 ? UNP Q6VPE5 ?   ?   'expression tag'      163 47 
3 9NF1 HIS C 164 ? UNP Q6VPE5 ?   ?   'expression tag'      164 48 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 8930  ? 
1 MORE         -109  ? 
1 'SSA (A^2)'  15690 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 13  ? GLY A 33  ? THR A 13  GLY A 33  1 ? 21 
HELX_P HELX_P2  AA2 GLN A 35  ? LEU A 38  ? GLN A 35  LEU A 38  5 ? 4  
HELX_P HELX_P3  AA3 SER A 74  ? GLU A 94  ? SER A 74  GLU A 94  1 ? 21 
HELX_P HELX_P4  AA4 ASP A 96  ? LYS A 98  ? ASP A 96  LYS A 98  5 ? 3  
HELX_P HELX_P5  AA5 PRO A 108 ? GLN A 110 ? PRO A 108 GLN A 110 5 ? 3  
HELX_P HELX_P6  AA6 HIS A 124 ? ASN A 131 ? HIS A 124 ASN A 131 1 ? 8  
HELX_P HELX_P7  AA7 SER A 133 ? THR A 142 ? SER A 133 THR A 142 1 ? 10 
HELX_P HELX_P8  AA8 THR B 13  ? GLY B 33  ? THR B 13  GLY B 33  1 ? 21 
HELX_P HELX_P9  AA9 GLN B 35  ? LEU B 38  ? GLN B 35  LEU B 38  5 ? 4  
HELX_P HELX_P10 AB1 SER B 74  ? GLU B 94  ? SER B 74  GLU B 94  1 ? 21 
HELX_P HELX_P11 AB2 ASP B 96  ? LYS B 98  ? ASP B 96  LYS B 98  5 ? 3  
HELX_P HELX_P12 AB3 PRO B 108 ? GLN B 110 ? PRO B 108 GLN B 110 5 ? 3  
HELX_P HELX_P13 AB4 HIS B 124 ? ASN B 131 ? HIS B 124 ASN B 131 1 ? 8  
HELX_P HELX_P14 AB5 SER B 133 ? THR B 142 ? SER B 133 THR B 142 1 ? 10 
HELX_P HELX_P15 AB6 THR C 13  ? GLY C 33  ? THR C 13  GLY C 33  1 ? 21 
HELX_P HELX_P16 AB7 GLN C 35  ? LEU C 38  ? GLN C 35  LEU C 38  5 ? 4  
HELX_P HELX_P17 AB8 SER C 74  ? GLU C 94  ? SER C 74  GLU C 94  1 ? 21 
HELX_P HELX_P18 AB9 ASP C 96  ? LYS C 98  ? ASP C 96  LYS C 98  5 ? 3  
HELX_P HELX_P19 AC1 PRO C 108 ? GLN C 110 ? PRO C 108 GLN C 110 5 ? 3  
HELX_P HELX_P20 AC2 HIS C 124 ? ASN C 131 ? HIS C 124 ASN C 131 1 ? 8  
HELX_P HELX_P21 AC3 SER C 133 ? THR C 142 ? SER C 133 THR C 142 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 8 ? 
AA2 ? 8 ? 
AA3 ? 8 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA1 7 8 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
AA2 5 6 ? parallel      
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? anti-parallel 
AA3 5 6 ? parallel      
AA3 6 7 ? anti-parallel 
AA3 7 8 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG B 117 ? PHE B 118 ? ARG B 117 PHE B 118 
AA1 2 MET B 112 ? ASP B 114 ? MET B 112 ASP B 114 
AA1 3 ILE A 100 ? MET A 107 ? ILE A 100 MET A 107 
AA1 4 ILE A 63  ? ARG A 70  ? ILE A 63  ARG A 70  
AA1 5 VAL A 2   ? SER A 8   ? VAL A 2   SER A 8   
AA1 6 GLN A 40  ? GLN A 46  ? GLN A 40  GLN A 46  
AA1 7 VAL C 51  ? LEU C 53  ? VAL C 51  LEU C 53  
AA1 8 VAL C 56  ? GLN C 57  ? VAL C 56  GLN C 57  
AA2 1 VAL A 56  ? GLN A 57  ? VAL A 56  GLN A 57  
AA2 2 VAL A 51  ? LEU A 53  ? VAL A 51  LEU A 53  
AA2 3 GLN B 40  ? GLN B 46  ? GLN B 40  GLN B 46  
AA2 4 VAL B 2   ? SER B 8   ? VAL B 2   SER B 8   
AA2 5 ILE B 63  ? ARG B 70  ? ILE B 63  ARG B 70  
AA2 6 ILE B 100 ? MET B 107 ? ILE B 100 MET B 107 
AA2 7 MET C 112 ? ASP C 114 ? MET C 112 ASP C 114 
AA2 8 ARG C 117 ? PHE C 118 ? ARG C 117 PHE C 118 
AA3 1 ARG A 117 ? PHE A 118 ? ARG A 117 PHE A 118 
AA3 2 MET A 112 ? ASP A 114 ? MET A 112 ASP A 114 
AA3 3 ILE C 100 ? MET C 107 ? ILE C 100 MET C 107 
AA3 4 ILE C 63  ? ARG C 70  ? ILE C 63  ARG C 70  
AA3 5 VAL C 2   ? SER C 8   ? VAL C 2   SER C 8   
AA3 6 GLN C 40  ? GLN C 46  ? GLN C 40  GLN C 46  
AA3 7 VAL B 51  ? LEU B 53  ? VAL B 51  LEU B 53  
AA3 8 VAL B 56  ? GLN B 57  ? VAL B 56  GLN B 57  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ARG B 117 ? O ARG B 117 N ASP B 114 ? N ASP B 114 
AA1 2 3 O VAL B 113 ? O VAL B 113 N VAL A 102 ? N VAL A 102 
AA1 3 4 O GLY A 105 ? O GLY A 105 N HIS A 69  ? N HIS A 69  
AA1 4 5 O HIS A 66  ? O HIS A 66  N MET A 4   ? N MET A 4   
AA1 5 6 N VAL A 5   ? N VAL A 5   O GLN A 44  ? O GLN A 44  
AA1 6 7 N VAL A 41  ? N VAL A 41  O PHE C 52  ? O PHE C 52  
AA1 7 8 N LEU C 53  ? N LEU C 53  O VAL C 56  ? O VAL C 56  
AA2 1 2 O VAL A 56  ? O VAL A 56  N LEU A 53  ? N LEU A 53  
AA2 2 3 N PHE A 52  ? N PHE A 52  O VAL B 41  ? O VAL B 41  
AA2 3 4 O ASN B 42  ? O ASN B 42  N TYR B 3   ? N TYR B 3   
AA2 4 5 N TYR B 6   ? N TYR B 6   O PHE B 64  ? O PHE B 64  
AA2 5 6 N GLY B 67  ? N GLY B 67  O GLY B 105 ? O GLY B 105 
AA2 6 7 N VAL B 102 ? N VAL B 102 O VAL C 113 ? O VAL C 113 
AA2 7 8 N ASP C 114 ? N ASP C 114 O ARG C 117 ? O ARG C 117 
AA3 1 2 O ARG A 117 ? O ARG A 117 N ASP A 114 ? N ASP A 114 
AA3 2 3 N VAL A 113 ? N VAL A 113 O VAL C 102 ? O VAL C 102 
AA3 3 4 O GLY C 105 ? O GLY C 105 N GLY C 67  ? N GLY C 67  
AA3 4 5 O PHE C 64  ? O PHE C 64  N TYR C 6   ? N TYR C 6   
AA3 5 6 N VAL C 5   ? N VAL C 5   O GLN C 44  ? O GLN C 44  
AA3 6 7 O VAL C 41  ? O VAL C 41  N PHE B 52  ? N PHE B 52  
AA3 7 8 N LEU B 53  ? N LEU B 53  O VAL B 56  ? O VAL B 56  
# 
_pdbx_entry_details.entry_id                   9NF1 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OE2 A GLU 141 ? ? O A HOH 301 ? ? 2.04 
2 1 O   B HOH 455 ? ? O B HOH 467 ? ? 2.06 
3 1 O   B HOH 332 ? ? O B HOH 434 ? ? 2.14 
4 1 O   B SER 147 ? ? O B HOH 301 ? ? 2.16 
5 1 O   B HOH 327 ? ? O B HOH 438 ? ? 2.16 
6 1 O   C HOH 389 ? ? O C HOH 479 ? ? 2.18 
7 1 O   A HOH 324 ? ? O A HOH 382 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O C HOH 334 ? ? 1_555 O C HOH 334 ? ? 3_554 2.02 
2 1 O B HOH 359 ? ? 1_555 O C HOH 308 ? ? 8_455 2.15 
3 1 O A HOH 422 ? ? 1_555 O B HOH 341 ? ? 5_545 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 10  ? ? 80.86   -6.30   
2 1 PRO A 122 ? ? -33.94  -85.07  
3 1 ASN A 143 ? ? -103.24 57.25   
4 1 LEU B 132 ? ? -143.90 -158.19 
5 1 ASN B 143 ? ? -100.69 58.14   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 ASN B 131 ? ? LEU B 132 ? ? 139.66  
2 1 LEU B 132 ? ? SER B 133 ? ? -138.02 
# 
loop_
_pdbx_struct_special_symmetry.id 
_pdbx_struct_special_symmetry.PDB_model_num 
_pdbx_struct_special_symmetry.auth_asym_id 
_pdbx_struct_special_symmetry.auth_comp_id 
_pdbx_struct_special_symmetry.auth_seq_id 
_pdbx_struct_special_symmetry.PDB_ins_code 
_pdbx_struct_special_symmetry.label_asym_id 
_pdbx_struct_special_symmetry.label_comp_id 
_pdbx_struct_special_symmetry.label_seq_id 
1 1 A HOH 371 ? G HOH . 
2 1 A HOH 467 ? G HOH . 
3 1 C HOH 447 ? I HOH . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? B HOH 494 ? 5.97 . 
2 1 O ? B HOH 495 ? 6.43 . 
3 1 O ? B HOH 496 ? 7.10 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A SER 147 ? A SER 147 
2  1 Y 1 A ARG 148 ? A ARG 148 
3  1 Y 1 A THR 149 ? A THR 149 
4  1 Y 1 A GLU 150 ? A GLU 150 
5  1 Y 1 A ASN 151 ? A ASN 151 
6  1 Y 1 A LEU 152 ? A LEU 152 
7  1 Y 1 A TYR 153 ? A TYR 153 
8  1 Y 1 A PHE 154 ? A PHE 154 
9  1 Y 1 A GLN 155 ? A GLN 155 
10 1 Y 1 A GLY 156 ? A GLY 156 
11 1 Y 1 A LEU 157 ? A LEU 157 
12 1 Y 1 A GLU 158 ? A GLU 158 
13 1 Y 1 A HIS 159 ? A HIS 159 
14 1 Y 1 A HIS 160 ? A HIS 160 
15 1 Y 1 A HIS 161 ? A HIS 161 
16 1 Y 1 A HIS 162 ? A HIS 162 
17 1 Y 1 A HIS 163 ? A HIS 163 
18 1 Y 1 A HIS 164 ? A HIS 164 
19 1 Y 1 B ARG 148 ? B ARG 148 
20 1 Y 1 B THR 149 ? B THR 149 
21 1 Y 1 B GLU 150 ? B GLU 150 
22 1 Y 1 B ASN 151 ? B ASN 151 
23 1 Y 1 B LEU 152 ? B LEU 152 
24 1 Y 1 B TYR 153 ? B TYR 153 
25 1 Y 1 B PHE 154 ? B PHE 154 
26 1 Y 1 B GLN 155 ? B GLN 155 
27 1 Y 1 B GLY 156 ? B GLY 156 
28 1 Y 1 B LEU 157 ? B LEU 157 
29 1 Y 1 B GLU 158 ? B GLU 158 
30 1 Y 1 B HIS 159 ? B HIS 159 
31 1 Y 1 B HIS 160 ? B HIS 160 
32 1 Y 1 B HIS 161 ? B HIS 161 
33 1 Y 1 B HIS 162 ? B HIS 162 
34 1 Y 1 B HIS 163 ? B HIS 163 
35 1 Y 1 B HIS 164 ? B HIS 164 
36 1 Y 1 C SER 147 ? C SER 147 
37 1 Y 1 C ARG 148 ? C ARG 148 
38 1 Y 1 C THR 149 ? C THR 149 
39 1 Y 1 C GLU 150 ? C GLU 150 
40 1 Y 1 C ASN 151 ? C ASN 151 
41 1 Y 1 C LEU 152 ? C LEU 152 
42 1 Y 1 C TYR 153 ? C TYR 153 
43 1 Y 1 C PHE 154 ? C PHE 154 
44 1 Y 1 C GLN 155 ? C GLN 155 
45 1 Y 1 C GLY 156 ? C GLY 156 
46 1 Y 1 C LEU 157 ? C LEU 157 
47 1 Y 1 C GLU 158 ? C GLU 158 
48 1 Y 1 C HIS 159 ? C HIS 159 
49 1 Y 1 C HIS 160 ? C HIS 160 
50 1 Y 1 C HIS 161 ? C HIS 161 
51 1 Y 1 C HIS 162 ? C HIS 162 
52 1 Y 1 C HIS 163 ? C HIS 163 
53 1 Y 1 C HIS 164 ? C HIS 164 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
GLN N    N N N 74  
GLN CA   C N S 75  
GLN C    C N N 76  
GLN O    O N N 77  
GLN CB   C N N 78  
GLN CG   C N N 79  
GLN CD   C N N 80  
GLN OE1  O N N 81  
GLN NE2  N N N 82  
GLN OXT  O N N 83  
GLN H    H N N 84  
GLN H2   H N N 85  
GLN HA   H N N 86  
GLN HB2  H N N 87  
GLN HB3  H N N 88  
GLN HG2  H N N 89  
GLN HG3  H N N 90  
GLN HE21 H N N 91  
GLN HE22 H N N 92  
GLN HXT  H N N 93  
GLU N    N N N 94  
GLU CA   C N S 95  
GLU C    C N N 96  
GLU O    O N N 97  
GLU CB   C N N 98  
GLU CG   C N N 99  
GLU CD   C N N 100 
GLU OE1  O N N 101 
GLU OE2  O N N 102 
GLU OXT  O N N 103 
GLU H    H N N 104 
GLU H2   H N N 105 
GLU HA   H N N 106 
GLU HB2  H N N 107 
GLU HB3  H N N 108 
GLU HG2  H N N 109 
GLU HG3  H N N 110 
GLU HE2  H N N 111 
GLU HXT  H N N 112 
GLY N    N N N 113 
GLY CA   C N N 114 
GLY C    C N N 115 
GLY O    O N N 116 
GLY OXT  O N N 117 
GLY H    H N N 118 
GLY H2   H N N 119 
GLY HA2  H N N 120 
GLY HA3  H N N 121 
GLY HXT  H N N 122 
HIS N    N N N 123 
HIS CA   C N S 124 
HIS C    C N N 125 
HIS O    O N N 126 
HIS CB   C N N 127 
HIS CG   C Y N 128 
HIS ND1  N Y N 129 
HIS CD2  C Y N 130 
HIS CE1  C Y N 131 
HIS NE2  N Y N 132 
HIS OXT  O N N 133 
HIS H    H N N 134 
HIS H2   H N N 135 
HIS HA   H N N 136 
HIS HB2  H N N 137 
HIS HB3  H N N 138 
HIS HD1  H N N 139 
HIS HD2  H N N 140 
HIS HE1  H N N 141 
HIS HE2  H N N 142 
HIS HXT  H N N 143 
HOH O    O N N 144 
HOH H1   H N N 145 
HOH H2   H N N 146 
ILE N    N N N 147 
ILE CA   C N S 148 
ILE C    C N N 149 
ILE O    O N N 150 
ILE CB   C N S 151 
ILE CG1  C N N 152 
ILE CG2  C N N 153 
ILE CD1  C N N 154 
ILE OXT  O N N 155 
ILE H    H N N 156 
ILE H2   H N N 157 
ILE HA   H N N 158 
ILE HB   H N N 159 
ILE HG12 H N N 160 
ILE HG13 H N N 161 
ILE HG21 H N N 162 
ILE HG22 H N N 163 
ILE HG23 H N N 164 
ILE HD11 H N N 165 
ILE HD12 H N N 166 
ILE HD13 H N N 167 
ILE HXT  H N N 168 
LEU N    N N N 169 
LEU CA   C N S 170 
LEU C    C N N 171 
LEU O    O N N 172 
LEU CB   C N N 173 
LEU CG   C N N 174 
LEU CD1  C N N 175 
LEU CD2  C N N 176 
LEU OXT  O N N 177 
LEU H    H N N 178 
LEU H2   H N N 179 
LEU HA   H N N 180 
LEU HB2  H N N 181 
LEU HB3  H N N 182 
LEU HG   H N N 183 
LEU HD11 H N N 184 
LEU HD12 H N N 185 
LEU HD13 H N N 186 
LEU HD21 H N N 187 
LEU HD22 H N N 188 
LEU HD23 H N N 189 
LEU HXT  H N N 190 
LYS N    N N N 191 
LYS CA   C N S 192 
LYS C    C N N 193 
LYS O    O N N 194 
LYS CB   C N N 195 
LYS CG   C N N 196 
LYS CD   C N N 197 
LYS CE   C N N 198 
LYS NZ   N N N 199 
LYS OXT  O N N 200 
LYS H    H N N 201 
LYS H2   H N N 202 
LYS HA   H N N 203 
LYS HB2  H N N 204 
LYS HB3  H N N 205 
LYS HG2  H N N 206 
LYS HG3  H N N 207 
LYS HD2  H N N 208 
LYS HD3  H N N 209 
LYS HE2  H N N 210 
LYS HE3  H N N 211 
LYS HZ1  H N N 212 
LYS HZ2  H N N 213 
LYS HZ3  H N N 214 
LYS HXT  H N N 215 
MET N    N N N 216 
MET CA   C N S 217 
MET C    C N N 218 
MET O    O N N 219 
MET CB   C N N 220 
MET CG   C N N 221 
MET SD   S N N 222 
MET CE   C N N 223 
MET OXT  O N N 224 
MET H    H N N 225 
MET H2   H N N 226 
MET HA   H N N 227 
MET HB2  H N N 228 
MET HB3  H N N 229 
MET HG2  H N N 230 
MET HG3  H N N 231 
MET HE1  H N N 232 
MET HE2  H N N 233 
MET HE3  H N N 234 
MET HXT  H N N 235 
PHE N    N N N 236 
PHE CA   C N S 237 
PHE C    C N N 238 
PHE O    O N N 239 
PHE CB   C N N 240 
PHE CG   C Y N 241 
PHE CD1  C Y N 242 
PHE CD2  C Y N 243 
PHE CE1  C Y N 244 
PHE CE2  C Y N 245 
PHE CZ   C Y N 246 
PHE OXT  O N N 247 
PHE H    H N N 248 
PHE H2   H N N 249 
PHE HA   H N N 250 
PHE HB2  H N N 251 
PHE HB3  H N N 252 
PHE HD1  H N N 253 
PHE HD2  H N N 254 
PHE HE1  H N N 255 
PHE HE2  H N N 256 
PHE HZ   H N N 257 
PHE HXT  H N N 258 
PRO N    N N N 259 
PRO CA   C N S 260 
PRO C    C N N 261 
PRO O    O N N 262 
PRO CB   C N N 263 
PRO CG   C N N 264 
PRO CD   C N N 265 
PRO OXT  O N N 266 
PRO H    H N N 267 
PRO HA   H N N 268 
PRO HB2  H N N 269 
PRO HB3  H N N 270 
PRO HG2  H N N 271 
PRO HG3  H N N 272 
PRO HD2  H N N 273 
PRO HD3  H N N 274 
PRO HXT  H N N 275 
SER N    N N N 276 
SER CA   C N S 277 
SER C    C N N 278 
SER O    O N N 279 
SER CB   C N N 280 
SER OG   O N N 281 
SER OXT  O N N 282 
SER H    H N N 283 
SER H2   H N N 284 
SER HA   H N N 285 
SER HB2  H N N 286 
SER HB3  H N N 287 
SER HG   H N N 288 
SER HXT  H N N 289 
SO4 S    S N N 290 
SO4 O1   O N N 291 
SO4 O2   O N N 292 
SO4 O3   O N N 293 
SO4 O4   O N N 294 
THR N    N N N 295 
THR CA   C N S 296 
THR C    C N N 297 
THR O    O N N 298 
THR CB   C N R 299 
THR OG1  O N N 300 
THR CG2  C N N 301 
THR OXT  O N N 302 
THR H    H N N 303 
THR H2   H N N 304 
THR HA   H N N 305 
THR HB   H N N 306 
THR HG1  H N N 307 
THR HG21 H N N 308 
THR HG22 H N N 309 
THR HG23 H N N 310 
THR HXT  H N N 311 
TRP N    N N N 312 
TRP CA   C N S 313 
TRP C    C N N 314 
TRP O    O N N 315 
TRP CB   C N N 316 
TRP CG   C Y N 317 
TRP CD1  C Y N 318 
TRP CD2  C Y N 319 
TRP NE1  N Y N 320 
TRP CE2  C Y N 321 
TRP CE3  C Y N 322 
TRP CZ2  C Y N 323 
TRP CZ3  C Y N 324 
TRP CH2  C Y N 325 
TRP OXT  O N N 326 
TRP H    H N N 327 
TRP H2   H N N 328 
TRP HA   H N N 329 
TRP HB2  H N N 330 
TRP HB3  H N N 331 
TRP HD1  H N N 332 
TRP HE1  H N N 333 
TRP HE3  H N N 334 
TRP HZ2  H N N 335 
TRP HZ3  H N N 336 
TRP HH2  H N N 337 
TRP HXT  H N N 338 
TYR N    N N N 339 
TYR CA   C N S 340 
TYR C    C N N 341 
TYR O    O N N 342 
TYR CB   C N N 343 
TYR CG   C Y N 344 
TYR CD1  C Y N 345 
TYR CD2  C Y N 346 
TYR CE1  C Y N 347 
TYR CE2  C Y N 348 
TYR CZ   C Y N 349 
TYR OH   O N N 350 
TYR OXT  O N N 351 
TYR H    H N N 352 
TYR H2   H N N 353 
TYR HA   H N N 354 
TYR HB2  H N N 355 
TYR HB3  H N N 356 
TYR HD1  H N N 357 
TYR HD2  H N N 358 
TYR HE1  H N N 359 
TYR HE2  H N N 360 
TYR HH   H N N 361 
TYR HXT  H N N 362 
VAL N    N N N 363 
VAL CA   C N S 364 
VAL C    C N N 365 
VAL O    O N N 366 
VAL CB   C N N 367 
VAL CG1  C N N 368 
VAL CG2  C N N 369 
VAL OXT  O N N 370 
VAL H    H N N 371 
VAL H2   H N N 372 
VAL HA   H N N 373 
VAL HB   H N N 374 
VAL HG11 H N N 375 
VAL HG12 H N N 376 
VAL HG13 H N N 377 
VAL HG21 H N N 378 
VAL HG22 H N N 379 
VAL HG23 H N N 380 
VAL HXT  H N N 381 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
GLN N   CA   sing N N 70  
GLN N   H    sing N N 71  
GLN N   H2   sing N N 72  
GLN CA  C    sing N N 73  
GLN CA  CB   sing N N 74  
GLN CA  HA   sing N N 75  
GLN C   O    doub N N 76  
GLN C   OXT  sing N N 77  
GLN CB  CG   sing N N 78  
GLN CB  HB2  sing N N 79  
GLN CB  HB3  sing N N 80  
GLN CG  CD   sing N N 81  
GLN CG  HG2  sing N N 82  
GLN CG  HG3  sing N N 83  
GLN CD  OE1  doub N N 84  
GLN CD  NE2  sing N N 85  
GLN NE2 HE21 sing N N 86  
GLN NE2 HE22 sing N N 87  
GLN OXT HXT  sing N N 88  
GLU N   CA   sing N N 89  
GLU N   H    sing N N 90  
GLU N   H2   sing N N 91  
GLU CA  C    sing N N 92  
GLU CA  CB   sing N N 93  
GLU CA  HA   sing N N 94  
GLU C   O    doub N N 95  
GLU C   OXT  sing N N 96  
GLU CB  CG   sing N N 97  
GLU CB  HB2  sing N N 98  
GLU CB  HB3  sing N N 99  
GLU CG  CD   sing N N 100 
GLU CG  HG2  sing N N 101 
GLU CG  HG3  sing N N 102 
GLU CD  OE1  doub N N 103 
GLU CD  OE2  sing N N 104 
GLU OE2 HE2  sing N N 105 
GLU OXT HXT  sing N N 106 
GLY N   CA   sing N N 107 
GLY N   H    sing N N 108 
GLY N   H2   sing N N 109 
GLY CA  C    sing N N 110 
GLY CA  HA2  sing N N 111 
GLY CA  HA3  sing N N 112 
GLY C   O    doub N N 113 
GLY C   OXT  sing N N 114 
GLY OXT HXT  sing N N 115 
HIS N   CA   sing N N 116 
HIS N   H    sing N N 117 
HIS N   H2   sing N N 118 
HIS CA  C    sing N N 119 
HIS CA  CB   sing N N 120 
HIS CA  HA   sing N N 121 
HIS C   O    doub N N 122 
HIS C   OXT  sing N N 123 
HIS CB  CG   sing N N 124 
HIS CB  HB2  sing N N 125 
HIS CB  HB3  sing N N 126 
HIS CG  ND1  sing Y N 127 
HIS CG  CD2  doub Y N 128 
HIS ND1 CE1  doub Y N 129 
HIS ND1 HD1  sing N N 130 
HIS CD2 NE2  sing Y N 131 
HIS CD2 HD2  sing N N 132 
HIS CE1 NE2  sing Y N 133 
HIS CE1 HE1  sing N N 134 
HIS NE2 HE2  sing N N 135 
HIS OXT HXT  sing N N 136 
HOH O   H1   sing N N 137 
HOH O   H2   sing N N 138 
ILE N   CA   sing N N 139 
ILE N   H    sing N N 140 
ILE N   H2   sing N N 141 
ILE CA  C    sing N N 142 
ILE CA  CB   sing N N 143 
ILE CA  HA   sing N N 144 
ILE C   O    doub N N 145 
ILE C   OXT  sing N N 146 
ILE CB  CG1  sing N N 147 
ILE CB  CG2  sing N N 148 
ILE CB  HB   sing N N 149 
ILE CG1 CD1  sing N N 150 
ILE CG1 HG12 sing N N 151 
ILE CG1 HG13 sing N N 152 
ILE CG2 HG21 sing N N 153 
ILE CG2 HG22 sing N N 154 
ILE CG2 HG23 sing N N 155 
ILE CD1 HD11 sing N N 156 
ILE CD1 HD12 sing N N 157 
ILE CD1 HD13 sing N N 158 
ILE OXT HXT  sing N N 159 
LEU N   CA   sing N N 160 
LEU N   H    sing N N 161 
LEU N   H2   sing N N 162 
LEU CA  C    sing N N 163 
LEU CA  CB   sing N N 164 
LEU CA  HA   sing N N 165 
LEU C   O    doub N N 166 
LEU C   OXT  sing N N 167 
LEU CB  CG   sing N N 168 
LEU CB  HB2  sing N N 169 
LEU CB  HB3  sing N N 170 
LEU CG  CD1  sing N N 171 
LEU CG  CD2  sing N N 172 
LEU CG  HG   sing N N 173 
LEU CD1 HD11 sing N N 174 
LEU CD1 HD12 sing N N 175 
LEU CD1 HD13 sing N N 176 
LEU CD2 HD21 sing N N 177 
LEU CD2 HD22 sing N N 178 
LEU CD2 HD23 sing N N 179 
LEU OXT HXT  sing N N 180 
LYS N   CA   sing N N 181 
LYS N   H    sing N N 182 
LYS N   H2   sing N N 183 
LYS CA  C    sing N N 184 
LYS CA  CB   sing N N 185 
LYS CA  HA   sing N N 186 
LYS C   O    doub N N 187 
LYS C   OXT  sing N N 188 
LYS CB  CG   sing N N 189 
LYS CB  HB2  sing N N 190 
LYS CB  HB3  sing N N 191 
LYS CG  CD   sing N N 192 
LYS CG  HG2  sing N N 193 
LYS CG  HG3  sing N N 194 
LYS CD  CE   sing N N 195 
LYS CD  HD2  sing N N 196 
LYS CD  HD3  sing N N 197 
LYS CE  NZ   sing N N 198 
LYS CE  HE2  sing N N 199 
LYS CE  HE3  sing N N 200 
LYS NZ  HZ1  sing N N 201 
LYS NZ  HZ2  sing N N 202 
LYS NZ  HZ3  sing N N 203 
LYS OXT HXT  sing N N 204 
MET N   CA   sing N N 205 
MET N   H    sing N N 206 
MET N   H2   sing N N 207 
MET CA  C    sing N N 208 
MET CA  CB   sing N N 209 
MET CA  HA   sing N N 210 
MET C   O    doub N N 211 
MET C   OXT  sing N N 212 
MET CB  CG   sing N N 213 
MET CB  HB2  sing N N 214 
MET CB  HB3  sing N N 215 
MET CG  SD   sing N N 216 
MET CG  HG2  sing N N 217 
MET CG  HG3  sing N N 218 
MET SD  CE   sing N N 219 
MET CE  HE1  sing N N 220 
MET CE  HE2  sing N N 221 
MET CE  HE3  sing N N 222 
MET OXT HXT  sing N N 223 
PHE N   CA   sing N N 224 
PHE N   H    sing N N 225 
PHE N   H2   sing N N 226 
PHE CA  C    sing N N 227 
PHE CA  CB   sing N N 228 
PHE CA  HA   sing N N 229 
PHE C   O    doub N N 230 
PHE C   OXT  sing N N 231 
PHE CB  CG   sing N N 232 
PHE CB  HB2  sing N N 233 
PHE CB  HB3  sing N N 234 
PHE CG  CD1  doub Y N 235 
PHE CG  CD2  sing Y N 236 
PHE CD1 CE1  sing Y N 237 
PHE CD1 HD1  sing N N 238 
PHE CD2 CE2  doub Y N 239 
PHE CD2 HD2  sing N N 240 
PHE CE1 CZ   doub Y N 241 
PHE CE1 HE1  sing N N 242 
PHE CE2 CZ   sing Y N 243 
PHE CE2 HE2  sing N N 244 
PHE CZ  HZ   sing N N 245 
PHE OXT HXT  sing N N 246 
PRO N   CA   sing N N 247 
PRO N   CD   sing N N 248 
PRO N   H    sing N N 249 
PRO CA  C    sing N N 250 
PRO CA  CB   sing N N 251 
PRO CA  HA   sing N N 252 
PRO C   O    doub N N 253 
PRO C   OXT  sing N N 254 
PRO CB  CG   sing N N 255 
PRO CB  HB2  sing N N 256 
PRO CB  HB3  sing N N 257 
PRO CG  CD   sing N N 258 
PRO CG  HG2  sing N N 259 
PRO CG  HG3  sing N N 260 
PRO CD  HD2  sing N N 261 
PRO CD  HD3  sing N N 262 
PRO OXT HXT  sing N N 263 
SER N   CA   sing N N 264 
SER N   H    sing N N 265 
SER N   H2   sing N N 266 
SER CA  C    sing N N 267 
SER CA  CB   sing N N 268 
SER CA  HA   sing N N 269 
SER C   O    doub N N 270 
SER C   OXT  sing N N 271 
SER CB  OG   sing N N 272 
SER CB  HB2  sing N N 273 
SER CB  HB3  sing N N 274 
SER OG  HG   sing N N 275 
SER OXT HXT  sing N N 276 
SO4 S   O1   doub N N 277 
SO4 S   O2   doub N N 278 
SO4 S   O3   sing N N 279 
SO4 S   O4   sing N N 280 
THR N   CA   sing N N 281 
THR N   H    sing N N 282 
THR N   H2   sing N N 283 
THR CA  C    sing N N 284 
THR CA  CB   sing N N 285 
THR CA  HA   sing N N 286 
THR C   O    doub N N 287 
THR C   OXT  sing N N 288 
THR CB  OG1  sing N N 289 
THR CB  CG2  sing N N 290 
THR CB  HB   sing N N 291 
THR OG1 HG1  sing N N 292 
THR CG2 HG21 sing N N 293 
THR CG2 HG22 sing N N 294 
THR CG2 HG23 sing N N 295 
THR OXT HXT  sing N N 296 
TRP N   CA   sing N N 297 
TRP N   H    sing N N 298 
TRP N   H2   sing N N 299 
TRP CA  C    sing N N 300 
TRP CA  CB   sing N N 301 
TRP CA  HA   sing N N 302 
TRP C   O    doub N N 303 
TRP C   OXT  sing N N 304 
TRP CB  CG   sing N N 305 
TRP CB  HB2  sing N N 306 
TRP CB  HB3  sing N N 307 
TRP CG  CD1  doub Y N 308 
TRP CG  CD2  sing Y N 309 
TRP CD1 NE1  sing Y N 310 
TRP CD1 HD1  sing N N 311 
TRP CD2 CE2  doub Y N 312 
TRP CD2 CE3  sing Y N 313 
TRP NE1 CE2  sing Y N 314 
TRP NE1 HE1  sing N N 315 
TRP CE2 CZ2  sing Y N 316 
TRP CE3 CZ3  doub Y N 317 
TRP CE3 HE3  sing N N 318 
TRP CZ2 CH2  doub Y N 319 
TRP CZ2 HZ2  sing N N 320 
TRP CZ3 CH2  sing Y N 321 
TRP CZ3 HZ3  sing N N 322 
TRP CH2 HH2  sing N N 323 
TRP OXT HXT  sing N N 324 
TYR N   CA   sing N N 325 
TYR N   H    sing N N 326 
TYR N   H2   sing N N 327 
TYR CA  C    sing N N 328 
TYR CA  CB   sing N N 329 
TYR CA  HA   sing N N 330 
TYR C   O    doub N N 331 
TYR C   OXT  sing N N 332 
TYR CB  CG   sing N N 333 
TYR CB  HB2  sing N N 334 
TYR CB  HB3  sing N N 335 
TYR CG  CD1  doub Y N 336 
TYR CG  CD2  sing Y N 337 
TYR CD1 CE1  sing Y N 338 
TYR CD1 HD1  sing N N 339 
TYR CD2 CE2  doub Y N 340 
TYR CD2 HD2  sing N N 341 
TYR CE1 CZ   doub Y N 342 
TYR CE1 HE1  sing N N 343 
TYR CE2 CZ   sing Y N 344 
TYR CE2 HE2  sing N N 345 
TYR CZ  OH   sing N N 346 
TYR OH  HH   sing N N 347 
TYR OXT HXT  sing N N 348 
VAL N   CA   sing N N 349 
VAL N   H    sing N N 350 
VAL N   H2   sing N N 351 
VAL CA  C    sing N N 352 
VAL CA  CB   sing N N 353 
VAL CA  HA   sing N N 354 
VAL C   O    doub N N 355 
VAL C   OXT  sing N N 356 
VAL CB  CG1  sing N N 357 
VAL CB  CG2  sing N N 358 
VAL CB  HB   sing N N 359 
VAL CG1 HG11 sing N N 360 
VAL CG1 HG12 sing N N 361 
VAL CG1 HG13 sing N N 362 
VAL CG2 HG21 sing N N 363 
VAL CG2 HG22 sing N N 364 
VAL CG2 HG23 sing N N 365 
VAL OXT HXT  sing N N 366 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   3MF8 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9NF1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016668 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009971 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006792 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . PRO A 1 1   ? 9.89975   9.39591  -24.20369 1.000 27.66806 ? 1   PRO A N   1 
ATOM   2    C CA  . PRO A 1 1   ? 8.99208   10.40351 -23.66563 1.000 14.82132 ? 1   PRO A CA  1 
ATOM   3    C C   . PRO A 1 1   ? 9.29234   10.93817 -22.28094 1.000 16.04283 ? 1   PRO A C   1 
ATOM   4    O O   . PRO A 1 1   ? 10.06289  10.36457 -21.51746 1.000 16.26514 ? 1   PRO A O   1 
ATOM   5    C CB  . PRO A 1 1   ? 7.68115   9.64062  -23.67314 1.000 17.69719 ? 1   PRO A CB  1 
ATOM   6    C CG  . PRO A 1 1   ? 8.09602   8.24503  -23.18620 1.000 22.45760 ? 1   PRO A CG  1 
ATOM   7    C CD  . PRO A 1 1   ? 9.58159   8.09193  -23.59824 1.000 21.86785 ? 1   PRO A CD  1 
ATOM   8    N N   . VAL A 1 2   ? 8.68206   12.07419 -21.95769 1.000 11.76314 ? 2   VAL A N   1 
ATOM   9    C CA  . VAL A 1 2   ? 8.65169   12.57000 -20.59230 1.000 10.16130 ? 2   VAL A CA  1 
ATOM   10   C C   . VAL A 1 2   ? 7.18952   12.57751 -20.16649 1.000 11.65923 ? 2   VAL A C   1 
ATOM   11   O O   . VAL A 1 2   ? 6.34453   13.21542 -20.81698 1.000 11.23250 ? 2   VAL A O   1 
ATOM   12   C CB  . VAL A 1 2   ? 9.26847   13.96999 -20.46148 1.000 10.55976 ? 2   VAL A CB  1 
ATOM   13   C CG1 . VAL A 1 2   ? 9.09040   14.47401 -19.04164 1.000 11.57480 ? 2   VAL A CG1 1 
ATOM   14   C CG2 . VAL A 1 2   ? 10.73867  13.95078 -20.83069 1.000 11.23207 ? 2   VAL A CG2 1 
ATOM   15   N N   . TYR A 1 3   ? 6.88502   11.84241 -19.10407 1.000 10.84062 ? 3   TYR A N   1 
ATOM   16   C CA  . TYR A 1 3   ? 5.55350   11.80873 -18.51428 1.000 9.16563  ? 3   TYR A CA  1 
ATOM   17   C C   . TYR A 1 3   ? 5.60871   12.60877 -17.21753 1.000 12.97099 ? 3   TYR A C   1 
ATOM   18   O O   . TYR A 1 3   ? 6.17721   12.15052 -16.22439 1.000 11.31799 ? 3   TYR A O   1 
ATOM   19   C CB  . TYR A 1 3   ? 5.09716   10.37812 -18.25564 1.000 10.27124 ? 3   TYR A CB  1 
ATOM   20   C CG  . TYR A 1 3   ? 4.69743   9.65272  -19.51389 1.000 10.72577 ? 3   TYR A CG  1 
ATOM   21   C CD1 . TYR A 1 3   ? 3.43306   9.81437  -20.02852 1.000 11.06744 ? 3   TYR A CD1 1 
ATOM   22   C CD2 . TYR A 1 3   ? 5.56860   8.77615  -20.15379 1.000 13.21400 ? 3   TYR A CD2 1 
ATOM   23   C CE1 . TYR A 1 3   ? 3.02428   9.14125  -21.15975 1.000 11.92646 ? 3   TYR A CE1 1 
ATOM   24   C CE2 . TYR A 1 3   ? 5.18117   8.09363  -21.29038 1.000 11.48592 ? 3   TYR A CE2 1 
ATOM   25   C CZ  . TYR A 1 3   ? 3.90354   8.28323  -21.79563 1.000 11.65669 ? 3   TYR A CZ  1 
ATOM   26   O OH  . TYR A 1 3   ? 3.47759   7.61988  -22.92714 1.000 12.58872 ? 3   TYR A OH  1 
ATOM   27   N N   . MET A 1 4   ? 5.04367   13.81311 -17.24418 1.000 8.56276  ? 4   MET A N   1 
ATOM   28   C CA  . MET A 1 4   ? 4.87521   14.61979 -16.04594 1.000 8.97071  ? 4   MET A CA  1 
ATOM   29   C C   . MET A 1 4   ? 3.65261   14.09696 -15.29326 1.000 9.66219  ? 4   MET A C   1 
ATOM   30   O O   . MET A 1 4   ? 2.55143   14.04728 -15.85921 1.000 11.59858 ? 4   MET A O   1 
ATOM   31   C CB  . MET A 1 4   ? 4.67132   16.08870 -16.42383 1.000 9.69345  ? 4   MET A CB  1 
ATOM   32   C CG  . MET A 1 4   ? 5.82413   16.84691 -17.07369 1.000 10.96012 ? 4   MET A CG  1 
ATOM   33   S SD  . MET A 1 4   ? 7.50741   16.47673 -16.56074 1.000 10.13715 ? 4   MET A SD  1 
ATOM   34   C CE  . MET A 1 4   ? 7.59303   17.65455 -15.23344 1.000 15.71848 ? 4   MET A CE  1 
ATOM   35   N N   . VAL A 1 5   ? 3.81608   13.71254 -14.02446 1.000 9.29233  ? 5   VAL A N   1 
ATOM   36   C CA  . VAL A 1 5   ? 2.72566   13.08533 -13.27163 1.000 9.61130  ? 5   VAL A CA  1 
ATOM   37   C C   . VAL A 1 5   ? 2.42998   13.92361 -12.03373 1.000 9.29505  ? 5   VAL A C   1 
ATOM   38   O O   . VAL A 1 5   ? 3.22881   13.96459 -11.08962 1.000 11.43711 ? 5   VAL A O   1 
ATOM   39   C CB  . VAL A 1 5   ? 3.04532   11.63247 -12.88571 1.000 8.71835  ? 5   VAL A CB  1 
ATOM   40   C CG1 . VAL A 1 5   ? 1.84269   11.02084 -12.17490 1.000 10.61223 ? 5   VAL A CG1 1 
ATOM   41   C CG2 . VAL A 1 5   ? 3.39910   10.83616 -14.11489 1.000 9.93246  ? 5   VAL A CG2 1 
ATOM   42   N N   . TYR A 1 6   ? 1.26245   14.56926 -12.02737 1.000 8.57602  ? 6   TYR A N   1 
ATOM   43   C CA  . TYR A 1 6   ? 0.87719   15.53993 -11.00794 1.000 8.84572  ? 6   TYR A CA  1 
ATOM   44   C C   . TYR A 1 6   ? -0.00990  14.84978 -9.98946  1.000 8.82266  ? 6   TYR A C   1 
ATOM   45   O O   . TYR A 1 6   ? -1.12739  14.42476 -10.30584 1.000 10.02076 ? 6   TYR A O   1 
ATOM   46   C CB  . TYR A 1 6   ? 0.17652   16.73694 -11.64895 1.000 7.72164  ? 6   TYR A CB  1 
ATOM   47   C CG  . TYR A 1 6   ? 1.07112   17.42004 -12.64173 1.000 8.84581  ? 6   TYR A CG  1 
ATOM   48   C CD1 . TYR A 1 6   ? 1.99078   18.37846 -12.23854 1.000 8.01842  ? 6   TYR A CD1 1 
ATOM   49   C CD2 . TYR A 1 6   ? 1.02989   17.07671 -13.99111 1.000 8.45121  ? 6   TYR A CD2 1 
ATOM   50   C CE1 . TYR A 1 6   ? 2.85286   18.99181 -13.15839 1.000 8.46332  ? 6   TYR A CE1 1 
ATOM   51   C CE2 . TYR A 1 6   ? 1.86855   17.70421 -14.91380 1.000 9.54645  ? 6   TYR A CE2 1 
ATOM   52   C CZ  . TYR A 1 6   ? 2.77957   18.65053 -14.48768 1.000 7.66844  ? 6   TYR A CZ  1 
ATOM   53   O OH  . TYR A 1 6   ? 3.61154   19.24448 -15.42227 1.000 9.50420  ? 6   TYR A OH  1 
ATOM   54   N N   . VAL A 1 7   ? 0.50563   14.71584 -8.76943  1.000 9.90696  ? 7   VAL A N   1 
ATOM   55   C CA  . VAL A 1 7   ? -0.17613  13.99392 -7.70889  1.000 11.24831 ? 7   VAL A CA  1 
ATOM   56   C C   . VAL A 1 7   ? -0.05664  14.79870 -6.42331  1.000 13.82249 ? 7   VAL A C   1 
ATOM   57   O O   . VAL A 1 7   ? 0.75698   15.71886 -6.31191  1.000 11.24386 ? 7   VAL A O   1 
ATOM   58   C CB  . VAL A 1 7   ? 0.40577   12.57438 -7.52168  1.000 12.32141 ? 7   VAL A CB  1 
ATOM   59   C CG1 . VAL A 1 7   ? 0.15567   11.73512 -8.76237  1.000 14.75302 ? 7   VAL A CG1 1 
ATOM   60   C CG2 . VAL A 1 7   ? 1.89559   12.65392 -7.19839  1.000 12.47132 ? 7   VAL A CG2 1 
ATOM   61   N N   . SER A 1 8   ? -0.89291  14.44264 -5.44782  1.000 12.16932 ? 8   SER A N   1 
ATOM   62   C CA  . SER A 1 8   ? -0.85471  15.10447 -4.14947  1.000 11.06750 ? 8   SER A CA  1 
ATOM   63   C C   . SER A 1 8   ? 0.23428   14.50192 -3.27152  1.000 14.09720 ? 8   SER A C   1 
ATOM   64   O O   . SER A 1 8   ? 0.50679   13.29688 -3.32650  1.000 15.38380 ? 8   SER A O   1 
ATOM   65   C CB  . SER A 1 8   ? -2.21755  15.00962 -3.46044  1.000 12.80311 ? 8   SER A CB  1 
ATOM   66   O OG  . SER A 1 8   ? -3.19572  15.73971 -4.18465  1.000 16.52130 ? 8   SER A OG  1 
ATOM   67   N N   . GLN A 1 9   ? 0.87785   15.36004 -2.48658  1.000 13.96486 ? 9   GLN A N   1 
ATOM   68   C CA  . GLN A 1 9   ? 1.90461   14.91096 -1.55501  1.000 18.95054 ? 9   GLN A CA  1 
ATOM   69   C C   . GLN A 1 9   ? 1.36444   13.79291 -0.67104  1.000 19.00649 ? 9   GLN A C   1 
ATOM   70   O O   . GLN A 1 9   ? 0.26172   13.89417 -0.13276  1.000 20.67133 ? 9   GLN A O   1 
ATOM   71   C CB  . GLN A 1 9   ? 2.37006   16.08379 -0.69571  1.000 23.32549 ? 9   GLN A CB  1 
ATOM   72   C CG  . GLN A 1 9   ? 3.29771   15.67186 0.43819   1.000 24.72125 ? 9   GLN A CG  1 
ATOM   73   C CD  . GLN A 1 9   ? 4.75414   15.90653 0.10522   1.000 36.23574 ? 9   GLN A CD  1 
ATOM   74   O OE1 . GLN A 1 9   ? 5.16136   15.81880 -1.05504  1.000 35.88023 ? 9   GLN A OE1 1 
ATOM   75   N NE2 . GLN A 1 9   ? 5.55637   16.19011 1.12621   1.000 41.91440 ? 9   GLN A NE2 1 
ATOM   76   N N   . ASP A 1 10  ? 2.12916   12.70613 -0.56248  1.000 25.02720 ? 10  ASP A N   1 
ATOM   77   C CA  . ASP A 1 10  ? 1.89944   11.57008 0.32346   1.000 27.88990 ? 10  ASP A CA  1 
ATOM   78   C C   . ASP A 1 10  ? 0.87074   10.59154 -0.24913  1.000 25.47632 ? 10  ASP A C   1 
ATOM   79   O O   . ASP A 1 10  ? 0.64881   9.54227  0.35563   1.000 28.71715 ? 10  ASP A O   1 
ATOM   80   C CB  . ASP A 1 10  ? 1.43099   11.98963 1.73168   1.000 32.55013 ? 10  ASP A CB  1 
ATOM   81   C CG  . ASP A 1 10  ? 2.52330   12.66996 2.53856   1.000 30.88624 ? 10  ASP A CG  1 
ATOM   82   O OD1 . ASP A 1 10  ? 3.71925   12.52153 2.20095   1.000 36.22068 ? 10  ASP A OD1 1 
ATOM   83   O OD2 . ASP A 1 10  ? 2.16823   13.38640 3.50165   1.000 35.98643 ? 10  ASP A OD2 1 
ATOM   84   N N   . ARG A 1 11  ? 0.20913   10.89661 -1.37132  1.000 24.06889 ? 11  ARG A N   1 
ATOM   85   C CA  . ARG A 1 11  ? -0.80248  9.96740  -1.86317  1.000 19.56032 ? 11  ARG A CA  1 
ATOM   86   C C   . ARG A 1 11  ? -0.15760  8.70049  -2.41987  1.000 19.38934 ? 11  ARG A C   1 
ATOM   87   O O   . ARG A 1 11  ? -0.76113  7.61926  -2.36319  1.000 26.56816 ? 11  ARG A O   1 
ATOM   88   C CB  . ARG A 1 11  ? -1.69744  10.64372 -2.91225  1.000 19.92916 ? 11  ARG A CB  1 
ATOM   89   C CG  . ARG A 1 11  ? -2.50394  9.67649  -3.78075  1.000 18.27542 ? 11  ARG A CG  1 
ATOM   90   C CD  . ARG A 1 11  ? -3.70023  9.11787  -3.00771  1.000 25.21924 ? 11  ARG A CD  1 
ATOM   91   N NE  . ARG A 1 11  ? -4.56347  8.28080  -3.83703  1.000 27.86957 ? 11  ARG A NE  1 
ATOM   92   C CZ  . ARG A 1 11  ? -4.28439  7.02896  -4.17975  1.000 28.06461 ? 11  ARG A CZ  1 
ATOM   93   N NH1 . ARG A 1 11  ? -3.13777  6.45845  -3.84275  1.000 28.89368 ? 11  ARG A NH1 1 
ATOM   94   N NH2 . ARG A 1 11  ? -5.17188  6.33439  -4.88890  1.000 32.42138 ? 11  ARG A NH2 1 
ATOM   95   N N   . LEU A 1 12  ? 1.06857   8.80163  -2.92712  1.000 20.60781 ? 12  LEU A N   1 
ATOM   96   C CA  . LEU A 1 12  ? 1.82322   7.65224  -3.41670  1.000 22.26295 ? 12  LEU A CA  1 
ATOM   97   C C   . LEU A 1 12  ? 3.03535   7.43180  -2.52074  1.000 20.20041 ? 12  LEU A C   1 
ATOM   98   O O   . LEU A 1 12  ? 3.87172   8.32821  -2.37072  1.000 19.65976 ? 12  LEU A O   1 
ATOM   99   C CB  . LEU A 1 12  ? 2.28039   7.85671  -4.86322  1.000 19.60775 ? 12  LEU A CB  1 
ATOM   100  C CG  . LEU A 1 12  ? 1.21244   8.08979  -5.93920  1.000 20.45397 ? 12  LEU A CG  1 
ATOM   101  C CD1 . LEU A 1 12  ? 1.88314   8.31639  -7.30154  1.000 17.81821 ? 12  LEU A CD1 1 
ATOM   102  C CD2 . LEU A 1 12  ? 0.24851   6.92748  -5.99246  1.000 21.59599 ? 12  LEU A CD2 1 
ATOM   103  N N   . THR A 1 13  ? 3.14245   6.23409  -1.94893  1.000 19.33428 ? 13  THR A N   1 
ATOM   104  C CA  . THR A 1 13  ? 4.34461   5.84507  -1.23668  1.000 22.83944 ? 13  THR A CA  1 
ATOM   105  C C   . THR A 1 13  ? 5.47925   5.64658  -2.23847  1.000 21.27443 ? 13  THR A C   1 
ATOM   106  O O   . THR A 1 13  ? 5.25630   5.66151  -3.45064  1.000 19.46783 ? 13  THR A O   1 
ATOM   107  C CB  . THR A 1 13  ? 4.10196   4.55691  -0.45428  1.000 23.89654 ? 13  THR A CB  1 
ATOM   108  O OG1 . THR A 1 13  ? 3.80439   3.49933  -1.37220  1.000 25.02881 ? 13  THR A OG1 1 
ATOM   109  C CG2 . THR A 1 13  ? 2.95268   4.72628  0.53048   1.000 27.02603 ? 13  THR A CG2 1 
ATOM   110  N N   . PRO A 1 14  ? 6.71849   5.46043  -1.76849  1.000 21.28709 ? 14  PRO A N   1 
ATOM   111  C CA  . PRO A 1 14  ? 7.80112   5.16533  -2.72484  1.000 20.71249 ? 14  PRO A CA  1 
ATOM   112  C C   . PRO A 1 14  ? 7.53737   3.93182  -3.57738  1.000 22.49931 ? 14  PRO A C   1 
ATOM   113  O O   . PRO A 1 14  ? 7.85579   3.92447  -4.77675  1.000 18.68224 ? 14  PRO A O   1 
ATOM   114  C CB  . PRO A 1 14  ? 9.02076   4.98562  -1.81542  1.000 24.05380 ? 14  PRO A CB  1 
ATOM   115  C CG  . PRO A 1 14  ? 8.74322   5.87421  -0.66318  1.000 25.24030 ? 14  PRO A CG  1 
ATOM   116  C CD  . PRO A 1 14  ? 7.25148   5.85262  -0.44706  1.000 23.73518 ? 14  PRO A CD  1 
ATOM   117  N N   . SER A 1 15  ? 6.96212   2.87517  -2.99970  1.000 18.89642 ? 15  SER A N   1 
ATOM   118  C CA  . SER A 1 15  ? 6.68543   1.69551  -3.81074  1.000 19.33757 ? 15  SER A CA  1 
ATOM   119  C C   . SER A 1 15  ? 5.57007   1.97686  -4.80476  1.000 16.63690 ? 15  SER A C   1 
ATOM   120  O O   . SER A 1 15  ? 5.59438   1.47118  -5.93205  1.000 21.52547 ? 15  SER A O   1 
ATOM   121  C CB  . SER A 1 15  ? 6.31975   0.50019  -2.92669  1.000 26.21988 ? 15  SER A CB  1 
ATOM   122  O OG  . SER A 1 15  ? 5.48802   0.90026  -1.85402  1.000 30.41585 ? 15  SER A OG  1 
ATOM   123  N N   . ALA A 1 16  ? 4.57953   2.77769  -4.40162  1.000 22.20965 ? 16  ALA A N   1 
ATOM   124  C CA  . ALA A 1 16  ? 3.48913   3.11247  -5.31070  1.000 17.66133 ? 16  ALA A CA  1 
ATOM   125  C C   . ALA A 1 16  ? 3.98086   4.00531  -6.43849  1.000 15.60254 ? 16  ALA A C   1 
ATOM   126  O O   . ALA A 1 16  ? 3.53662   3.86831  -7.58184  1.000 15.83677 ? 16  ALA A O   1 
ATOM   127  C CB  . ALA A 1 16  ? 2.34883   3.78750  -4.55049  1.000 21.67245 ? 16  ALA A CB  1 
ATOM   128  N N   . LYS A 1 17  ? 4.89670   4.92697  -6.13809  1.000 16.79362 ? 17  LYS A N   1 
ATOM   129  C CA  . LYS A 1 17  ? 5.50090   5.71697  -7.20458  1.000 17.64561 ? 17  LYS A CA  1 
ATOM   130  C C   . LYS A 1 17  ? 6.24202   4.81508  -8.17524  1.000 16.71614 ? 17  LYS A C   1 
ATOM   131  O O   . LYS A 1 17  ? 6.09436   4.93774  -9.39556  1.000 16.26671 ? 17  LYS A O   1 
ATOM   132  C CB  . LYS A 1 17  ? 6.44540   6.76538  -6.61889  1.000 17.50223 ? 17  LYS A CB  1 
ATOM   133  C CG  . LYS A 1 17  ? 5.74005   7.96252  -6.01879  1.000 20.45296 ? 17  LYS A CG  1 
ATOM   134  C CD  . LYS A 1 17  ? 6.76626   8.98275  -5.54219  1.000 21.94327 ? 17  LYS A CD  1 
ATOM   135  C CE  . LYS A 1 17  ? 6.11379   10.07926 -4.73167  1.000 22.06763 ? 17  LYS A CE  1 
ATOM   136  N NZ  . LYS A 1 17  ? 7.13523   10.79590 -3.92066  1.000 25.34020 ? 17  LYS A NZ  1 
ATOM   137  N N   . HIS A 1 18  ? 7.03930   3.88167  -7.64713  1.000 17.16860 ? 18  HIS A N   1 
ATOM   138  C CA  . HIS A 1 18  ? 7.72082   2.93907  -8.51980  1.000 18.41631 ? 18  HIS A CA  1 
ATOM   139  C C   . HIS A 1 18  ? 6.72766   2.14202  -9.35375  1.000 15.58712 ? 18  HIS A C   1 
ATOM   140  O O   . HIS A 1 18  ? 6.93336   1.94921  -10.55376 1.000 16.51217 ? 18  HIS A O   1 
ATOM   141  C CB  . HIS A 1 18  ? 8.60892   2.00709  -7.69351  1.000 19.66520 ? 18  HIS A CB  1 
ATOM   142  C CG  . HIS A 1 18  ? 9.55725   1.19746  -8.51991  1.000 22.17275 ? 18  HIS A CG  1 
ATOM   143  N ND1 . HIS A 1 18  ? 9.18299   0.03434  -9.15804  1.000 31.32187 ? 18  HIS A ND1 1 
ATOM   144  C CD2 . HIS A 1 18  ? 10.85486  1.40481  -8.84833  1.000 27.63139 ? 18  HIS A CD2 1 
ATOM   145  C CE1 . HIS A 1 18  ? 10.21640  -0.45545 -9.81980  1.000 26.97289 ? 18  HIS A CE1 1 
ATOM   146  N NE2 . HIS A 1 18  ? 11.24356  0.35726  -9.64787  1.000 29.04322 ? 18  HIS A NE2 1 
ATOM   147  N N   . ALA A 1 19  ? 5.63278   1.68646  -8.74112  1.000 17.01897 ? 19  ALA A N   1 
ATOM   148  C CA  . ALA A 1 19  ? 4.65509   0.89678  -9.48080  1.000 16.35628 ? 19  ALA A CA  1 
ATOM   149  C C   . ALA A 1 19  ? 3.98682   1.72109  -10.57363 1.000 17.63100 ? 19  ALA A C   1 
ATOM   150  O O   . ALA A 1 19  ? 3.75860   1.21798  -11.67827 1.000 17.72832 ? 19  ALA A O   1 
ATOM   151  C CB  . ALA A 1 19  ? 3.60557   0.32580  -8.52829  1.000 19.57318 ? 19  ALA A CB  1 
ATOM   152  N N   . VAL A 1 20  ? 3.64365   2.97992  -10.27409 1.000 13.65577 ? 20  VAL A N   1 
ATOM   153  C CA  . VAL A 1 20  ? 3.03381   3.84711  -11.28122 1.000 13.16699 ? 20  VAL A CA  1 
ATOM   154  C C   . VAL A 1 20  ? 4.02168   4.15653  -12.39893 1.000 14.58560 ? 20  VAL A C   1 
ATOM   155  O O   . VAL A 1 20  ? 3.66668   4.13067  -13.58595 1.000 14.49850 ? 20  VAL A O   1 
ATOM   156  C CB  . VAL A 1 20  ? 2.50516   5.13241  -10.62014 1.000 12.78160 ? 20  VAL A CB  1 
ATOM   157  C CG1 . VAL A 1 20  ? 2.14393   6.17475  -11.69640 1.000 12.06846 ? 20  VAL A CG1 1 
ATOM   158  C CG2 . VAL A 1 20  ? 1.31407   4.79221  -9.73987  1.000 16.08073 ? 20  VAL A CG2 1 
ATOM   159  N N   . ALA A 1 21  ? 5.26871   4.46709  -12.04125 1.000 13.79818 ? 21  ALA A N   1 
ATOM   160  C CA  . ALA A 1 21  ? 6.28739   4.69328  -13.05544 1.000 13.14434 ? 21  ALA A CA  1 
ATOM   161  C C   . ALA A 1 21  ? 6.47051   3.45462  -13.92398 1.000 19.37290 ? 21  ALA A C   1 
ATOM   162  O O   . ALA A 1 21  ? 6.60817   3.56467  -15.14469 1.000 16.94999 ? 21  ALA A O   1 
ATOM   163  C CB  . ALA A 1 21  ? 7.60443   5.09360  -12.39858 1.000 14.19496 ? 21  ALA A CB  1 
ATOM   164  N N   . LYS A 1 22  ? 6.44829   2.25923  -13.32309 1.000 15.99765 ? 22  LYS A N   1 
ATOM   165  C CA  . LYS A 1 22  ? 6.62669   1.07274  -14.15624 1.000 18.64033 ? 22  LYS A CA  1 
ATOM   166  C C   . LYS A 1 22  ? 5.41393   0.84876  -15.05770 1.000 17.64253 ? 22  LYS A C   1 
ATOM   167  O O   . LYS A 1 22  ? 5.56616   0.47011  -16.22389 1.000 19.37312 ? 22  LYS A O   1 
ATOM   168  C CB  . LYS A 1 22  ? 6.90056   -0.16853 -13.29941 1.000 23.47413 ? 22  LYS A CB  1 
ATOM   169  C CG  . LYS A 1 22  ? 6.41044   -1.47229 -13.93351 1.000 27.12328 ? 22  LYS A CG  1 
ATOM   170  C CD  . LYS A 1 22  ? 6.40277   -2.64468 -12.96471 1.000 29.11645 ? 22  LYS A CD  1 
ATOM   171  C CE  . LYS A 1 22  ? 6.42422   -3.97911 -13.73105 1.000 31.72503 ? 22  LYS A CE  1 
ATOM   172  N NZ  . LYS A 1 22  ? 5.61544   -5.05061 -13.08628 1.000 41.82016 ? 22  LYS A NZ  1 
ATOM   173  N N   . ALA A 1 23  ? 4.20402   1.09394  -14.54380 1.000 16.10510 ? 23  ALA A N   1 
ATOM   174  C CA  . ALA A 1 23  ? 2.99949   0.93614  -15.35538 1.000 14.46021 ? 23  ALA A CA  1 
ATOM   175  C C   . ALA A 1 23  ? 3.04902   1.82909  -16.59119 1.000 15.49839 ? 23  ALA A C   1 
ATOM   176  O O   . ALA A 1 23  ? 2.75587   1.38570  -17.70697 1.000 15.27048 ? 23  ALA A O   1 
ATOM   177  C CB  . ALA A 1 23  ? 1.76132   1.25255  -14.52450 1.000 16.54952 ? 23  ALA A CB  1 
ATOM   178  N N   . ILE A 1 24  ? 3.41904   3.09590  -16.40587 1.000 14.82308 ? 24  ILE A N   1 
ATOM   179  C CA  . ILE A 1 24  ? 3.51280   4.01875  -17.53093 1.000 14.43679 ? 24  ILE A CA  1 
ATOM   180  C C   . ILE A 1 24  ? 4.63185   3.60582  -18.46706 1.000 13.88788 ? 24  ILE A C   1 
ATOM   181  O O   . ILE A 1 24  ? 4.46889   3.61820  -19.69189 1.000 15.50539 ? 24  ILE A O   1 
ATOM   182  C CB  . ILE A 1 24  ? 3.70982   5.45598  -17.02551 1.000 11.60268 ? 24  ILE A CB  1 
ATOM   183  C CG1 . ILE A 1 24  ? 2.45389   5.90334  -16.27264 1.000 14.85378 ? 24  ILE A CG1 1 
ATOM   184  C CG2 . ILE A 1 24  ? 4.01974   6.36930  -18.19606 1.000 14.52238 ? 24  ILE A CG2 1 
ATOM   185  C CD1 . ILE A 1 24  ? 2.58533   7.24514  -15.54884 1.000 14.57999 ? 24  ILE A CD1 1 
ATOM   186  N N   . THR A 1 25  ? 5.79083   3.24615  -17.90234 1.000 15.77236 ? 25  THR A N   1 
ATOM   187  C CA  . THR A 1 25  ? 6.94347   2.89095  -18.71835 1.000 15.87496 ? 25  THR A CA  1 
ATOM   188  C C   . THR A 1 25  ? 6.66925   1.63676  -19.53496 1.000 14.05352 ? 25  THR A C   1 
ATOM   189  O O   . THR A 1 25  ? 6.99078   1.58019  -20.72484 1.000 16.29009 ? 25  THR A O   1 
ATOM   190  C CB  . THR A 1 25  ? 8.16257   2.69232  -17.82586 1.000 18.67213 ? 25  THR A CB  1 
ATOM   191  O OG1 . THR A 1 25  ? 8.43744   3.91450  -17.11620 1.000 18.63599 ? 25  THR A OG1 1 
ATOM   192  C CG2 . THR A 1 25  ? 9.36038   2.31637  -18.65220 1.000 18.79116 ? 25  THR A CG2 1 
ATOM   193  N N   . ASP A 1 26  ? 6.07433   0.62048  -18.90419 1.000 15.42759 ? 26  ASP A N   1 
ATOM   194  C CA  . ASP A 1 26  ? 5.76813   -0.62367 -19.60502 1.000 16.74999 ? 26  ASP A CA  1 
ATOM   195  C C   . ASP A 1 26  ? 4.72505   -0.41000 -20.69631 1.000 21.85876 ? 26  ASP A C   1 
ATOM   196  O O   . ASP A 1 26  ? 4.83060   -0.98932 -21.78127 1.000 19.98498 ? 26  ASP A O   1 
ATOM   197  C CB  . ASP A 1 26  ? 5.28847   -1.67303 -18.60041 1.000 20.02183 ? 26  ASP A CB  1 
ATOM   198  C CG  . ASP A 1 26  ? 6.41466   -2.22754 -17.74136 1.000 25.32013 ? 26  ASP A CG  1 
ATOM   199  O OD1 . ASP A 1 26  ? 7.60289   -1.99311 -18.05354 1.000 23.46452 ? 26  ASP A OD1 1 
ATOM   200  O OD2 . ASP A 1 26  ? 6.09595   -2.86726 -16.72016 1.000 23.38736 ? 26  ASP A OD2 1 
ATOM   201  N N   . ALA A 1 27  ? 3.70755   0.41306  -20.42453 1.000 17.20282 ? 27  ALA A N   1 
ATOM   202  C CA  . ALA A 1 27  ? 2.71957   0.74100  -21.44650 1.000 17.13429 ? 27  ALA A CA  1 
ATOM   203  C C   . ALA A 1 27  ? 3.37875   1.37950  -22.65808 1.000 16.50173 ? 27  ALA A C   1 
ATOM   204  O O   . ALA A 1 27  ? 3.09941   1.00435  -23.80259 1.000 15.65497 ? 27  ALA A O   1 
ATOM   205  C CB  . ALA A 1 27  ? 1.66148   1.68095  -20.86433 1.000 14.13610 ? 27  ALA A CB  1 
ATOM   206  N N   . HIS A 1 28  ? 4.25220   2.36209  -22.42082 1.000 14.10768 ? 28  HIS A N   1 
ATOM   207  C CA  . HIS A 1 28  ? 4.86614   3.08370  -23.52393 1.000 12.92557 ? 28  HIS A CA  1 
ATOM   208  C C   . HIS A 1 28  ? 5.79775   2.17169  -24.30530 1.000 18.00880 ? 28  HIS A C   1 
ATOM   209  O O   . HIS A 1 28  ? 5.72424   2.10246  -25.53752 1.000 16.82343 ? 28  HIS A O   1 
ATOM   210  C CB  . HIS A 1 28  ? 5.61368   4.31313  -23.01084 1.000 15.08427 ? 28  HIS A CB  1 
ATOM   211  C CG  . HIS A 1 28  ? 6.03581   5.24051  -24.10653 1.000 15.73048 ? 28  HIS A CG  1 
ATOM   212  N ND1 . HIS A 1 28  ? 5.27089   6.32272  -24.49483 1.000 14.28990 ? 28  HIS A ND1 1 
ATOM   213  C CD2 . HIS A 1 28  ? 7.10862   5.22177  -24.93296 1.000 18.98736 ? 28  HIS A CD2 1 
ATOM   214  C CE1 . HIS A 1 28  ? 5.86267   6.93410  -25.50599 1.000 18.23807 ? 28  HIS A CE1 1 
ATOM   215  N NE2 . HIS A 1 28  ? 6.98330   6.29196  -25.78596 1.000 19.20715 ? 28  HIS A NE2 1 
ATOM   216  N N   . ARG A 1 29  ? 6.66394   1.44503  -23.59640 1.000 16.87435 ? 29  ARG A N   1 
ATOM   217  C CA  . ARG A 1 29  ? 7.53014   0.46397  -24.24411 1.000 19.64605 ? 29  ARG A CA  1 
ATOM   218  C C   . ARG A 1 29  ? 6.71248   -0.55171 -25.03630 1.000 19.29831 ? 29  ARG A C   1 
ATOM   219  O O   . ARG A 1 29  ? 7.00063   -0.82314 -26.20920 1.000 24.82943 ? 29  ARG A O   1 
ATOM   220  C CB  . ARG A 1 29  ? 8.39228   -0.23479 -23.18307 1.000 22.49315 ? 29  ARG A CB  1 
ATOM   221  C CG  . ARG A 1 29  ? 9.72568   -0.76385 -23.69780 1.000 32.71242 ? 29  ARG A CG  1 
ATOM   222  C CD  . ARG A 1 29  ? 9.57291   -2.07613 -24.44462 1.000 33.89971 ? 29  ARG A CD  1 
ATOM   223  N NE  . ARG A 1 29  ? 10.77035  -2.90840 -24.36714 1.000 37.30861 ? 29  ARG A NE  1 
ATOM   224  C CZ  . ARG A 1 29  ? 11.77703  -2.85304 -25.23207 1.000 48.11954 ? 29  ARG A CZ  1 
ATOM   225  N NH1 . ARG A 1 29  ? 11.77063  -2.00356 -26.24804 1.000 45.15518 ? 29  ARG A NH1 1 
ATOM   226  N NH2 . ARG A 1 29  ? 12.81857  -3.66685 -25.07158 1.000 47.76449 ? 29  ARG A NH2 1 
ATOM   227  N N   . GLY A 1 30  ? 5.66894   -1.10569 -24.41745 1.000 20.32704 ? 30  GLY A N   1 
ATOM   228  C CA  . GLY A 1 30  ? 4.93166   -2.18506 -25.05466 1.000 22.55905 ? 30  GLY A CA  1 
ATOM   229  C C   . GLY A 1 30  ? 4.22488   -1.76060 -26.32634 1.000 23.38097 ? 30  GLY A C   1 
ATOM   230  O O   . GLY A 1 30  ? 4.18078   -2.51328 -27.30495 1.000 22.98775 ? 30  GLY A O   1 
ATOM   231  N N   . LEU A 1 31  ? 3.66631   -0.54879 -26.33897 1.000 19.81210 ? 31  LEU A N   1 
ATOM   232  C CA  . LEU A 1 31  ? 2.85610   -0.13329 -27.47392 1.000 20.16067 ? 31  LEU A CA  1 
ATOM   233  C C   . LEU A 1 31  ? 3.63586   0.61983  -28.54623 1.000 21.79712 ? 31  LEU A C   1 
ATOM   234  O O   . LEU A 1 31  ? 3.20091   0.62995  -29.70471 1.000 20.67719 ? 31  LEU A O   1 
ATOM   235  C CB  . LEU A 1 31  ? 1.67631   0.72107  -26.99391 1.000 18.32630 ? 31  LEU A CB  1 
ATOM   236  C CG  . LEU A 1 31  ? 0.52376   -0.04421 -26.32883 1.000 21.98691 ? 31  LEU A CG  1 
ATOM   237  C CD1 . LEU A 1 31  ? -0.38662  0.90211  -25.57873 1.000 19.21523 ? 31  LEU A CD1 1 
ATOM   238  C CD2 . LEU A 1 31  ? -0.27582  -0.84785 -27.35121 1.000 26.37626 ? 31  LEU A CD2 1 
ATOM   239  N N   . THR A 1 32  ? 4.77732   1.22968  -28.20944 1.000 16.89451 ? 32  THR A N   1 
ATOM   240  C CA  . THR A 1 32  ? 5.56037   1.98813  -29.17708 1.000 21.47925 ? 32  THR A CA  1 
ATOM   241  C C   . THR A 1 32  ? 6.87833   1.33159  -29.55990 1.000 24.28462 ? 32  THR A C   1 
ATOM   242  O O   . THR A 1 32  ? 7.49436   1.76321  -30.53981 1.000 24.89732 ? 32  THR A O   1 
ATOM   243  C CB  . THR A 1 32  ? 5.87954   3.38585  -28.63508 1.000 20.63472 ? 32  THR A CB  1 
ATOM   244  O OG1 . THR A 1 32  ? 6.81981   3.25457  -27.55494 1.000 19.62122 ? 32  THR A OG1 1 
ATOM   245  C CG2 . THR A 1 32  ? 4.60976   4.04970  -28.12237 1.000 18.92157 ? 32  THR A CG2 1 
ATOM   246  N N   . GLY A 1 33  ? 7.34901   0.34009  -28.79768 1.000 25.74962 ? 33  GLY A N   1 
ATOM   247  C CA  . GLY A 1 33  ? 8.65267   -0.25202 -29.02067 1.000 25.86531 ? 33  GLY A CA  1 
ATOM   248  C C   . GLY A 1 33  ? 9.83852   0.56238  -28.53773 1.000 26.48817 ? 33  GLY A C   1 
ATOM   249  O O   . GLY A 1 33  ? 10.95776  0.03186  -28.51288 1.000 30.15942 ? 33  GLY A O   1 
ATOM   250  N N   . THR A 1 34  ? 9.63406   1.82951  -28.16511 1.000 28.89560 ? 34  THR A N   1 
ATOM   251  C CA  . THR A 1 34  ? 10.70916  2.68581  -27.67440 1.000 31.15338 ? 34  THR A CA  1 
ATOM   252  C C   . THR A 1 34  ? 11.44208  2.00959  -26.52185 1.000 30.07903 ? 34  THR A C   1 
ATOM   253  O O   . THR A 1 34  ? 10.84183  1.28449  -25.72472 1.000 31.90156 ? 34  THR A O   1 
ATOM   254  C CB  . THR A 1 34  ? 10.12646  4.03881  -27.23652 1.000 30.56600 ? 34  THR A CB  1 
ATOM   255  O OG1 . THR A 1 34  ? 9.59962   4.72024  -28.38120 1.000 33.51804 ? 34  THR A OG1 1 
ATOM   256  C CG2 . THR A 1 34  ? 11.18967  4.93743  -26.60353 1.000 33.18018 ? 34  THR A CG2 1 
ATOM   257  N N   . GLN A 1 35  ? 12.75536  2.22100  -26.45696 1.000 33.78293 ? 35  GLN A N   1 
ATOM   258  C CA  . GLN A 1 35  ? 13.55112  1.54764  -25.44319 1.000 31.20468 ? 35  GLN A CA  1 
ATOM   259  C C   . GLN A 1 35  ? 13.11960  1.96624  -24.04722 1.000 31.61498 ? 35  GLN A C   1 
ATOM   260  O O   . GLN A 1 35  ? 12.71224  3.10836  -23.80256 1.000 29.34599 ? 35  GLN A O   1 
ATOM   261  C CB  . GLN A 1 35  ? 15.03918  1.83868  -25.62201 1.000 34.34380 ? 35  GLN A CB  1 
ATOM   262  C CG  . GLN A 1 35  ? 15.63022  1.21855  -26.86118 1.000 38.07016 ? 35  GLN A CG  1 
ATOM   263  C CD  . GLN A 1 35  ? 16.04219  2.27073  -27.85761 1.000 35.14049 ? 35  GLN A CD  1 
ATOM   264  O OE1 . GLN A 1 35  ? 15.33828  3.26489  -28.05216 1.000 40.65431 ? 35  GLN A OE1 1 
ATOM   265  N NE2 . GLN A 1 35  ? 17.18562  2.06382  -28.49781 1.000 36.96049 ? 35  GLN A NE2 1 
ATOM   266  N N   . HIS A 1 36  ? 13.23518  1.00410  -23.13673 1.000 28.23908 ? 36  HIS A N   1 
ATOM   267  C CA  . HIS A 1 36  ? 12.86551  1.17462  -21.74302 1.000 27.30575 ? 36  HIS A CA  1 
ATOM   268  C C   . HIS A 1 36  ? 13.43326  2.47493  -21.17570 1.000 22.27655 ? 36  HIS A C   1 
ATOM   269  O O   . HIS A 1 36  ? 12.70455  3.29221  -20.59638 1.000 20.08001 ? 36  HIS A O   1 
ATOM   270  C CB  . HIS A 1 36  ? 13.39354  -0.04825 -20.98949 1.000 36.02699 ? 36  HIS A CB  1 
ATOM   271  C CG  . HIS A 1 36  ? 12.51342  -0.52630 -19.88413 1.000 37.86202 ? 36  HIS A CG  1 
ATOM   272  N ND1 . HIS A 1 36  ? 12.39857  -1.86265 -19.56607 1.000 44.06361 ? 36  HIS A ND1 1 
ATOM   273  C CD2 . HIS A 1 36  ? 11.71621  0.13706  -19.01639 1.000 35.48596 ? 36  HIS A CD2 1 
ATOM   274  C CE1 . HIS A 1 36  ? 11.55802  -2.00280 -18.55714 1.000 42.12188 ? 36  HIS A CE1 1 
ATOM   275  N NE2 . HIS A 1 36  ? 11.13088  -0.80395 -18.20287 1.000 35.39615 ? 36  HIS A NE2 1 
ATOM   276  N N   . PHE A 1 37  ? 14.73209  2.71046  -21.39511 1.000 23.81379 ? 37  PHE A N   1 
ATOM   277  C CA  . PHE A 1 37  ? 15.46155  3.79318  -20.74131 1.000 20.41530 ? 37  PHE A CA  1 
ATOM   278  C C   . PHE A 1 37  ? 15.12662  5.17327  -21.29792 1.000 23.10075 ? 37  PHE A C   1 
ATOM   279  O O   . PHE A 1 37  ? 15.61086  6.17839  -20.76268 1.000 16.98383 ? 37  PHE A O   1 
ATOM   280  C CB  . PHE A 1 37  ? 16.96749  3.51803  -20.83447 1.000 20.70951 ? 37  PHE A CB  1 
ATOM   281  C CG  . PHE A 1 37  ? 17.45843  3.21604  -22.23584 1.000 22.57973 ? 37  PHE A CG  1 
ATOM   282  C CD1 . PHE A 1 37  ? 17.62473  4.23180  -23.16901 1.000 24.39542 ? 37  PHE A CD1 1 
ATOM   283  C CD2 . PHE A 1 37  ? 17.75498  1.91218  -22.61534 1.000 26.39051 ? 37  PHE A CD2 1 
ATOM   284  C CE1 . PHE A 1 37  ? 18.07990  3.95540  -24.44829 1.000 26.95030 ? 37  PHE A CE1 1 
ATOM   285  C CE2 . PHE A 1 37  ? 18.20970  1.63052  -23.90024 1.000 22.97782 ? 37  PHE A CE2 1 
ATOM   286  C CZ  . PHE A 1 37  ? 18.36787  2.65169  -24.81025 1.000 29.14228 ? 37  PHE A CZ  1 
ATOM   287  N N   . LEU A 1 38  ? 14.31010  5.25418  -22.33845 1.000 19.95028 ? 38  LEU A N   1 
ATOM   288  C CA  . LEU A 1 38  ? 13.93368  6.54491  -22.88841 1.000 22.88621 ? 38  LEU A CA  1 
ATOM   289  C C   . LEU A 1 38  ? 12.67698  7.10197  -22.23430 1.000 18.15773 ? 38  LEU A C   1 
ATOM   290  O O   . LEU A 1 38  ? 12.35819  8.27949  -22.44650 1.000 16.75175 ? 38  LEU A O   1 
ATOM   291  C CB  . LEU A 1 38  ? 13.73237  6.40961  -24.40081 1.000 24.75442 ? 38  LEU A CB  1 
ATOM   292  C CG  . LEU A 1 38  ? 15.01266  6.42300  -25.24764 1.000 22.05113 ? 38  LEU A CG  1 
ATOM   293  C CD1 . LEU A 1 38  ? 14.69737  6.65166  -26.70563 1.000 29.45353 ? 38  LEU A CD1 1 
ATOM   294  C CD2 . LEU A 1 38  ? 16.02632  7.43763  -24.75619 1.000 21.75773 ? 38  LEU A CD2 1 
ATOM   295  N N   . ALA A 1 39  ? 11.97922  6.29686  -21.43310 1.000 14.84975 ? 39  ALA A N   1 
ATOM   296  C CA  . ALA A 1 39  ? 10.74491  6.71781  -20.76602 1.000 14.21140 ? 39  ALA A CA  1 
ATOM   297  C C   . ALA A 1 39  ? 11.08011  7.36267  -19.42576 1.000 16.01740 ? 39  ALA A C   1 
ATOM   298  O O   . ALA A 1 39  ? 11.48742  6.67998  -18.47999 1.000 13.93923 ? 39  ALA A O   1 
ATOM   299  C CB  . ALA A 1 39  ? 9.79368   5.53585  -20.58726 1.000 21.02014 ? 39  ALA A CB  1 
ATOM   300  N N   . GLN A 1 40  ? 10.89117  8.67839  -19.33445 1.000 12.68472 ? 40  GLN A N   1 
ATOM   301  C CA  . GLN A 1 40  ? 11.07086  9.39206  -18.08165 1.000 10.80638 ? 40  GLN A CA  1 
ATOM   302  C C   . GLN A 1 40  ? 9.70005   9.61121  -17.46456 1.000 12.64433 ? 40  GLN A C   1 
ATOM   303  O O   . GLN A 1 40  ? 8.79060   10.09449 -18.13886 1.000 13.23018 ? 40  GLN A O   1 
ATOM   304  C CB  . GLN A 1 40  ? 11.76786  10.74139 -18.27607 1.000 11.12866 ? 40  GLN A CB  1 
ATOM   305  C CG  . GLN A 1 40  ? 11.79238  11.57328 -16.98896 1.000 10.60775 ? 40  GLN A CG  1 
ATOM   306  C CD  . GLN A 1 40  ? 12.55956  12.88709 -17.11746 1.000 13.02895 ? 40  GLN A CD  1 
ATOM   307  O OE1 . GLN A 1 40  ? 12.34211  13.81319 -16.33258 1.000 14.01588 ? 40  GLN A OE1 1 
ATOM   308  N NE2 . GLN A 1 40  ? 13.48846  12.96217 -18.07778 1.000 12.64483 ? 40  GLN A NE2 1 
ATOM   309  N N   . VAL A 1 41  ? 9.55571   9.23529  -16.20065 1.000 12.21952 ? 41  VAL A N   1 
ATOM   310  C CA  . VAL A 1 41  ? 8.37634   9.54762  -15.40430 1.000 11.91834 ? 41  VAL A CA  1 
ATOM   311  C C   . VAL A 1 41  ? 8.83228   10.50185 -14.31398 1.000 14.97726 ? 41  VAL A C   1 
ATOM   312  O O   . VAL A 1 41  ? 9.75348   10.19175 -13.54577 1.000 11.66029 ? 41  VAL A O   1 
ATOM   313  C CB  . VAL A 1 41  ? 7.71443   8.28804  -14.81795 1.000 12.39842 ? 41  VAL A CB  1 
ATOM   314  C CG1 . VAL A 1 41  ? 6.58481   8.67096  -13.88627 1.000 11.53060 ? 41  VAL A CG1 1 
ATOM   315  C CG2 . VAL A 1 41  ? 7.16698   7.41117  -15.92389 1.000 13.61765 ? 41  VAL A CG2 1 
ATOM   316  N N   . ASN A 1 42  ? 8.20537   11.67195 -14.25646 1.000 11.54465 ? 42  ASN A N   1 
ATOM   317  C CA  . ASN A 1 42  ? 8.67484   12.78324 -13.43463 1.000 11.15408 ? 42  ASN A CA  1 
ATOM   318  C C   . ASN A 1 42  ? 7.52384   13.18614 -12.52020 1.000 10.98897 ? 42  ASN A C   1 
ATOM   319  O O   . ASN A 1 42  ? 6.60464   13.89474 -12.94279 1.000 11.44202 ? 42  ASN A O   1 
ATOM   320  C CB  . ASN A 1 42  ? 9.15022   13.94399 -14.31077 1.000 10.90291 ? 42  ASN A CB  1 
ATOM   321  C CG  . ASN A 1 42  ? 10.01284  14.93193 -13.55398 1.000 14.53295 ? 42  ASN A CG  1 
ATOM   322  O OD1 . ASN A 1 42  ? 9.65903   15.34603 -12.44985 1.000 16.33579 ? 42  ASN A OD1 1 
ATOM   323  N ND2 . ASN A 1 42  ? 11.15657  15.29417 -14.12449 1.000 12.73081 ? 42  ASN A ND2 1 
ATOM   324  N N   . PHE A 1 43  ? 7.56846   12.73992 -11.26638 1.000 12.37197 ? 43  PHE A N   1 
ATOM   325  C CA  . PHE A 1 43  ? 6.47613   13.00266 -10.33560 1.000 10.95259 ? 43  PHE A CA  1 
ATOM   326  C C   . PHE A 1 43  ? 6.55837   14.41602 -9.78983  1.000 11.02356 ? 43  PHE A C   1 
ATOM   327  O O   . PHE A 1 43  ? 7.60254   14.83947 -9.28828  1.000 11.75013 ? 43  PHE A O   1 
ATOM   328  C CB  . PHE A 1 43  ? 6.49911   12.01683 -9.17506  1.000 11.80418 ? 43  PHE A CB  1 
ATOM   329  C CG  . PHE A 1 43  ? 5.99799   10.66182 -9.54241  1.000 10.90376 ? 43  PHE A CG  1 
ATOM   330  C CD1 . PHE A 1 43  ? 4.64111   10.41549 -9.65353  1.000 11.44317 ? 43  PHE A CD1 1 
ATOM   331  C CD2 . PHE A 1 43  ? 6.89356   9.63451  -9.78711  1.000 12.60878 ? 43  PHE A CD2 1 
ATOM   332  C CE1 . PHE A 1 43  ? 4.17049   9.14877  -9.98783  1.000 16.32697 ? 43  PHE A CE1 1 
ATOM   333  C CE2 . PHE A 1 43  ? 6.43678   8.37873  -10.13140 1.000 11.76727 ? 43  PHE A CE2 1 
ATOM   334  C CZ  . PHE A 1 43  ? 5.08312   8.13164  -10.22860 1.000 13.85145 ? 43  PHE A CZ  1 
ATOM   335  N N   . GLN A 1 44  ? 5.44399   15.13059 -9.87033  1.000 8.83828  ? 44  GLN A N   1 
ATOM   336  C CA  . GLN A 1 44  ? 5.32444   16.49055 -9.36418  1.000 9.64992  ? 44  GLN A CA  1 
ATOM   337  C C   . GLN A 1 44  ? 4.28171   16.47008 -8.26389  1.000 10.34454 ? 44  GLN A C   1 
ATOM   338  O O   . GLN A 1 44  ? 3.08691   16.36752 -8.54712  1.000 10.57360 ? 44  GLN A O   1 
ATOM   339  C CB  . GLN A 1 44  ? 4.90552   17.45256 -10.47358 1.000 9.94905  ? 44  GLN A CB  1 
ATOM   340  C CG  . GLN A 1 44  ? 5.90517   17.51382 -11.60849 1.000 9.77452  ? 44  GLN A CG  1 
ATOM   341  C CD  . GLN A 1 44  ? 7.15253   18.26735 -11.24641 1.000 13.17026 ? 44  GLN A CD  1 
ATOM   342  O OE1 . GLN A 1 44  ? 7.08843   19.39481 -10.76405 1.000 16.74673 ? 44  GLN A OE1 1 
ATOM   343  N NE2 . GLN A 1 44  ? 8.30356   17.64212 -11.45638 1.000 10.89257 ? 44  GLN A NE2 1 
ATOM   344  N N   . GLU A 1 45  ? 4.73351   16.58032 -7.02412  1.000 10.92231 ? 45  GLU A N   1 
ATOM   345  C CA  . GLU A 1 45  ? 3.85808   16.51615 -5.86269  1.000 11.03344 ? 45  GLU A CA  1 
ATOM   346  C C   . GLU A 1 45  ? 3.50736   17.91467 -5.36681  1.000 12.78919 ? 45  GLU A C   1 
ATOM   347  O O   . GLU A 1 45  ? 4.35042   18.81836 -5.35440  1.000 12.74822 ? 45  GLU A O   1 
ATOM   348  C CB  . GLU A 1 45  ? 4.52399   15.71457 -4.74269  1.000 10.93084 ? 45  GLU A CB  1 
ATOM   349  C CG  . GLU A 1 45  ? 4.64227   14.22026 -5.03309  1.000 15.58848 ? 45  GLU A CG  1 
ATOM   350  C CD  . GLU A 1 45  ? 5.43798   13.51359 -3.95413  1.000 18.85906 ? 45  GLU A CD  1 
ATOM   351  O OE1 . GLU A 1 45  ? 6.61790   13.84370 -3.79788  1.000 18.82847 ? 45  GLU A OE1 1 
ATOM   352  O OE2 . GLU A 1 45  ? 4.87029   12.65550 -3.25613  1.000 21.87710 ? 45  GLU A OE2 1 
ATOM   353  N N   . GLN A 1 46  ? 2.26037   18.08622 -4.95227  1.000 11.52639 ? 46  GLN A N   1 
ATOM   354  C CA  . GLN A 1 46  ? 1.80472   19.33377 -4.36253  1.000 13.17868 ? 46  GLN A CA  1 
ATOM   355  C C   . GLN A 1 46  ? 0.89005   18.98916 -3.20396  1.000 12.30444 ? 46  GLN A C   1 
ATOM   356  O O   . GLN A 1 46  ? 0.31793   17.89507 -3.16453  1.000 13.10988 ? 46  GLN A O   1 
ATOM   357  C CB  . GLN A 1 46  ? 1.05579   20.21023 -5.37663  1.000 13.52366 ? 46  GLN A CB  1 
ATOM   358  C CG  . GLN A 1 46  ? 1.95235   20.79920 -6.44291  1.000 10.15396 ? 46  GLN A CG  1 
ATOM   359  C CD  . GLN A 1 46  ? 2.74925   21.99823 -5.94731  1.000 11.39107 ? 46  GLN A CD  1 
ATOM   360  O OE1 . GLN A 1 46  ? 2.23381   22.85507 -5.22453  1.000 13.55626 ? 46  GLN A OE1 1 
ATOM   361  N NE2 . GLN A 1 46  ? 4.02220   22.04516 -6.31333  1.000 10.77846 ? 46  GLN A NE2 1 
ATOM   362  N N   . PRO A 1 47  ? 0.75224   19.88529 -2.23020  1.000 15.30873 ? 47  PRO A N   1 
ATOM   363  C CA  . PRO A 1 47  ? -0.15844  19.60016 -1.11608  1.000 13.76173 ? 47  PRO A CA  1 
ATOM   364  C C   . PRO A 1 47  ? -1.56319  19.29927 -1.61199  1.000 14.97652 ? 47  PRO A C   1 
ATOM   365  O O   . PRO A 1 47  ? -2.01707  19.84703 -2.62150  1.000 14.84396 ? 47  PRO A O   1 
ATOM   366  C CB  . PRO A 1 47  ? -0.11054  20.88331 -0.27407  1.000 17.25511 ? 47  PRO A CB  1 
ATOM   367  C CG  . PRO A 1 47  ? 0.43669   21.94491 -1.20166  1.000 20.12816 ? 47  PRO A CG  1 
ATOM   368  C CD  . PRO A 1 47  ? 1.39503   21.20673 -2.10103  1.000 15.35091 ? 47  PRO A CD  1 
ATOM   369  N N   . ALA A 1 48  ? -2.23973  18.37946 -0.92350  1.000 14.17313 ? 48  ALA A N   1 
ATOM   370  C CA  . ALA A 1 48  ? -3.63723  18.13992 -1.25787  1.000 12.77743 ? 48  ALA A CA  1 
ATOM   371  C C   . ALA A 1 48  ? -4.40687  19.43410 -1.05161  1.000 14.99278 ? 48  ALA A C   1 
ATOM   372  O O   . ALA A 1 48  ? -4.11520  20.20422 -0.12923  1.000 16.07616 ? 48  ALA A O   1 
ATOM   373  C CB  . ALA A 1 48  ? -4.23631  17.01659 -0.40580  1.000 16.31479 ? 48  ALA A CB  1 
ATOM   374  N N   . GLY A 1 49  ? -5.37522  19.67896 -1.92658  1.000 14.51948 ? 49  GLY A N   1 
ATOM   375  C CA  . GLY A 1 49  ? -6.11251  20.92350 -1.93551  1.000 15.14911 ? 49  GLY A CA  1 
ATOM   376  C C   . GLY A 1 49  ? -5.64669  21.91478 -2.98225  1.000 14.99238 ? 49  GLY A C   1 
ATOM   377  O O   . GLY A 1 49  ? -6.25672  22.97903 -3.12322  1.000 16.32832 ? 49  GLY A O   1 
ATOM   378  N N   . ASN A 1 50  ? -4.56004  21.62042 -3.69118  1.000 12.68380 ? 50  ASN A N   1 
ATOM   379  C CA  . ASN A 1 50  ? -4.14010  22.51029 -4.75914  1.000 11.24666 ? 50  ASN A CA  1 
ATOM   380  C C   . ASN A 1 50  ? -4.83109  22.21266 -6.07654  1.000 11.40142 ? 50  ASN A C   1 
ATOM   381  O O   . ASN A 1 50  ? -4.62519  22.95353 -7.03174  1.000 11.18525 ? 50  ASN A O   1 
ATOM   382  C CB  . ASN A 1 50  ? -2.62060  22.43212 -4.96140  1.000 13.74527 ? 50  ASN A CB  1 
ATOM   383  C CG  . ASN A 1 50  ? -1.86806  23.35931 -4.02761  1.000 14.46376 ? 50  ASN A CG  1 
ATOM   384  O OD1 . ASN A 1 50  ? -2.42791  23.84183 -3.03712  1.000 15.19132 ? 50  ASN A OD1 1 
ATOM   385  N ND2 . ASN A 1 50  ? -0.59014  23.61758 -4.33615  1.000 13.65635 ? 50  ASN A ND2 1 
ATOM   386  N N   . VAL A 1 51  ? -5.64268  21.15690 -6.15741  1.000 12.38968 ? 51  VAL A N   1 
ATOM   387  C CA  . VAL A 1 51  ? -6.41772  20.85200 -7.36189  1.000 9.70773  ? 51  VAL A CA  1 
ATOM   388  C C   . VAL A 1 51  ? -7.85973  21.29574 -7.14673  1.000 11.01939 ? 51  VAL A C   1 
ATOM   389  O O   . VAL A 1 51  ? -8.46089  21.00141 -6.10431  1.000 12.20529 ? 51  VAL A O   1 
ATOM   390  C CB  . VAL A 1 51  ? -6.35868  19.35603 -7.70973  1.000 11.50369 ? 51  VAL A CB  1 
ATOM   391  C CG1 . VAL A 1 51  ? -7.16561  19.07933 -8.95941  1.000 10.62951 ? 51  VAL A CG1 1 
ATOM   392  C CG2 . VAL A 1 51  ? -4.90344  18.89607 -7.89793  1.000 11.39145 ? 51  VAL A CG2 1 
ATOM   393  N N   . PHE A 1 52  ? -8.41290  22.01006 -8.12802  1.000 10.10456 ? 52  PHE A N   1 
ATOM   394  C CA  . PHE A 1 52  ? -9.81891  22.39373 -8.15264  1.000 9.95989  ? 52  PHE A CA  1 
ATOM   395  C C   . PHE A 1 52  ? -10.45778 21.80740 -9.40330  1.000 11.14677 ? 52  PHE A C   1 
ATOM   396  O O   . PHE A 1 52  ? -9.86016  21.81401 -10.47823 1.000 11.60555 ? 52  PHE A O   1 
ATOM   397  C CB  . PHE A 1 52  ? -9.98328  23.93532 -8.11550  1.000 11.12218 ? 52  PHE A CB  1 
ATOM   398  C CG  . PHE A 1 52  ? -9.54869  24.54568 -6.80939  1.000 11.96203 ? 52  PHE A CG  1 
ATOM   399  C CD1 . PHE A 1 52  ? -8.19821  24.69996 -6.51089  1.000 12.26542 ? 52  PHE A CD1 1 
ATOM   400  C CD2 . PHE A 1 52  ? -10.48874 24.93205 -5.86590  1.000 11.52328 ? 52  PHE A CD2 1 
ATOM   401  C CE1 . PHE A 1 52  ? -7.80237  25.23817 -5.30817  1.000 11.64993 ? 52  PHE A CE1 1 
ATOM   402  C CE2 . PHE A 1 52  ? -10.09337 25.45426 -4.65201  1.000 12.72677 ? 52  PHE A CE2 1 
ATOM   403  C CZ  . PHE A 1 52  ? -8.75655  25.60701 -4.36959  1.000 14.03468 ? 52  PHE A CZ  1 
ATOM   404  N N   . LEU A 1 53  ? -11.65946 21.26848 -9.26101  1.000 11.11859 ? 53  LEU A N   1 
ATOM   405  C CA  . LEU A 1 53  ? -12.44569 20.81018 -10.39871 1.000 12.33211 ? 53  LEU A CA  1 
ATOM   406  C C   . LEU A 1 53  ? -13.76090 21.56159 -10.33592 1.000 11.52095 ? 53  LEU A C   1 
ATOM   407  O O   . LEU A 1 53  ? -14.44732 21.51653 -9.30816  1.000 10.77788 ? 53  LEU A O   1 
ATOM   408  C CB  . LEU A 1 53  ? -12.67440 19.29108 -10.36034 1.000 12.13597 ? 53  LEU A CB  1 
ATOM   409  C CG  . LEU A 1 53  ? -11.43463 18.38817 -10.39135 1.000 10.77285 ? 53  LEU A CG  1 
ATOM   410  C CD1 . LEU A 1 53  ? -11.81241 16.92418 -10.27353 1.000 12.57185 ? 53  LEU A CD1 1 
ATOM   411  C CD2 . LEU A 1 53  ? -10.60616 18.61594 -11.66118 1.000 12.34393 ? 53  LEU A CD2 1 
ATOM   412  N N   . GLY A 1 54  ? -14.09036 22.28259 -11.40871 1.000 9.29762  ? 54  GLY A N   1 
ATOM   413  C CA  . GLY A 1 54  ? -15.27843 23.11582 -11.41509 1.000 11.35687 ? 54  GLY A CA  1 
ATOM   414  C C   . GLY A 1 54  ? -15.31296 24.14247 -10.30600 1.000 13.95109 ? 54  GLY A C   1 
ATOM   415  O O   . GLY A 1 54  ? -16.39743 24.54829 -9.87929  1.000 14.16856 ? 54  GLY A O   1 
ATOM   416  N N   . GLY A 1 55  ? -14.15440 24.57511 -9.82395  1.000 11.68768 ? 55  GLY A N   1 
ATOM   417  C CA  . GLY A 1 55  ? -14.09088 25.49851 -8.71632  1.000 12.87454 ? 55  GLY A CA  1 
ATOM   418  C C   . GLY A 1 55  ? -14.14569 24.86384 -7.34343  1.000 14.08825 ? 55  GLY A C   1 
ATOM   419  O O   . GLY A 1 55  ? -14.02673 25.59151 -6.34254  1.000 14.19968 ? 55  GLY A O   1 
ATOM   420  N N   . VAL A 1 56  ? -14.29276 23.53224 -7.26035  1.000 11.83890 ? 56  VAL A N   1 
ATOM   421  C CA  . VAL A 1 56  ? -14.36922 22.80263 -5.99418  1.000 13.38264 ? 56  VAL A CA  1 
ATOM   422  C C   . VAL A 1 56  ? -12.99907 22.24025 -5.63909  1.000 12.52820 ? 56  VAL A C   1 
ATOM   423  O O   . VAL A 1 56  ? -12.39756 21.49527 -6.42636  1.000 14.44409 ? 56  VAL A O   1 
ATOM   424  C CB  . VAL A 1 56  ? -15.41486 21.67477 -6.06911  1.000 15.58252 ? 56  VAL A CB  1 
ATOM   425  C CG1 . VAL A 1 56  ? -15.46353 20.87420 -4.75438  1.000 14.13804 ? 56  VAL A CG1 1 
ATOM   426  C CG2 . VAL A 1 56  ? -16.77717 22.25724 -6.38455  1.000 16.91695 ? 56  VAL A CG2 1 
ATOM   427  N N   . GLN A 1 57  ? -12.51788 22.58420 -4.44480  1.000 13.82624 ? 57  GLN A N   1 
ATOM   428  C CA  . GLN A 1 57  ? -11.26835 22.02856 -3.93149  1.000 13.43475 ? 57  GLN A CA  1 
ATOM   429  C C   . GLN A 1 57  ? -11.35473 20.50656 -3.80836  1.000 16.42348 ? 57  GLN A C   1 
ATOM   430  O O   . GLN A 1 57  ? -12.33110 19.96183 -3.27731  1.000 18.42979 ? 57  GLN A O   1 
ATOM   431  C CB  . GLN A 1 57  ? -10.94323 22.65868 -2.57565  1.000 13.75529 ? 57  GLN A CB  1 
ATOM   432  C CG  . GLN A 1 57  ? -9.64738  22.20572 -1.96100  1.000 16.58050 ? 57  GLN A CG  1 
ATOM   433  C CD  . GLN A 1 57  ? -9.25751  23.09310 -0.79737  1.000 25.09230 ? 57  GLN A CD  1 
ATOM   434  O OE1 . GLN A 1 57  ? -10.05896 23.32997 0.10788   1.000 25.70624 ? 57  GLN A OE1 1 
ATOM   435  N NE2 . GLN A 1 57  ? -8.02963  23.60516 -0.82118  1.000 27.45790 ? 57  GLN A NE2 1 
ATOM   436  N N   . GLN A 1 58  ? -10.32484 19.81935 -4.29387  1.000 13.71432 ? 58  GLN A N   1 
ATOM   437  C CA  . GLN A 1 58  ? -10.27123 18.36440 -4.27368  1.000 15.18991 ? 58  GLN A CA  1 
ATOM   438  C C   . GLN A 1 58  ? -9.42894  17.85956 -3.10886  1.000 16.59374 ? 58  GLN A C   1 
ATOM   439  O O   . GLN A 1 58  ? -8.58648  18.57262 -2.56146  1.000 17.65225 ? 58  GLN A O   1 
ATOM   440  C CB  . GLN A 1 58  ? -9.69455  17.82232 -5.58411  1.000 16.31377 ? 58  GLN A CB  1 
ATOM   441  C CG  . GLN A 1 58  ? -10.49831 18.23843 -6.82783  1.000 16.64736 ? 58  GLN A CG  1 
ATOM   442  C CD  . GLN A 1 58  ? -11.91459 17.69092 -6.78967  1.000 16.55626 ? 58  GLN A CD  1 
ATOM   443  O OE1 . GLN A 1 58  ? -12.11260 16.47511 -6.84274  1.000 24.65101 ? 58  GLN A OE1 1 
ATOM   444  N NE2 . GLN A 1 58  ? -12.90395 18.57732 -6.70193  1.000 16.31439 ? 58  GLN A NE2 1 
ATOM   445  N N   . GLY A 1 59  ? -9.68348  16.60783 -2.73289  1.000 19.42795 ? 59  GLY A N   1 
ATOM   446  C CA  . GLY A 1 59  ? -8.80096  15.88306 -1.84640  1.000 17.63998 ? 59  GLY A CA  1 
ATOM   447  C C   . GLY A 1 59  ? -7.55510  15.48812 -2.61264  1.000 19.84310 ? 59  GLY A C   1 
ATOM   448  O O   . GLY A 1 59  ? -7.20705  16.13673 -3.60166  1.000 23.70840 ? 59  GLY A O   1 
ATOM   449  N N   . GLY A 1 60  ? -6.88027  14.43250 -2.18991  1.000 21.56193 ? 60  GLY A N   1 
ATOM   450  C CA  . GLY A 1 60  ? -5.60199  14.13039 -2.79883  1.000 19.86419 ? 60  GLY A CA  1 
ATOM   451  C C   . GLY A 1 60  ? -5.62262  13.03537 -3.84366  1.000 15.91804 ? 60  GLY A C   1 
ATOM   452  O O   . GLY A 1 60  ? -4.57808  12.44695 -4.12509  1.000 19.32930 ? 60  GLY A O   1 
ATOM   453  N N   . ASP A 1 61  ? -6.78313  12.74270 -4.43875  1.000 18.57704 ? 61  ASP A N   1 
ATOM   454  C CA  . ASP A 1 61  ? -6.85331  11.58597 -5.32730  1.000 16.89029 ? 61  ASP A CA  1 
ATOM   455  C C   . ASP A 1 61  ? -6.57464  11.90123 -6.79427  1.000 16.12999 ? 61  ASP A C   1 
ATOM   456  O O   . ASP A 1 61  ? -6.18950  10.99591 -7.53777  1.000 16.18453 ? 61  ASP A O   1 
ATOM   457  C CB  . ASP A 1 61  ? -8.21582  10.90552 -5.21496  1.000 22.04363 ? 61  ASP A CB  1 
ATOM   458  C CG  . ASP A 1 61  ? -8.25514  9.87834  -4.10972  1.000 28.04787 ? 61  ASP A CG  1 
ATOM   459  O OD1 . ASP A 1 61  ? -9.30689  9.21747  -3.95268  1.000 33.87589 ? 61  ASP A OD1 1 
ATOM   460  O OD2 . ASP A 1 61  ? -7.23107  9.72050  -3.40704  1.000 26.00600 ? 61  ASP A OD2 1 
ATOM   461  N N   . THR A 1 62  ? -6.71529  13.13595 -7.24550  1.000 15.66754 ? 62  THR A N   1 
ATOM   462  C CA  . THR A 1 62  ? -6.56130  13.38281 -8.67270  1.000 12.44526 ? 62  THR A CA  1 
ATOM   463  C C   . THR A 1 62  ? -5.15294  13.03851 -9.14042  1.000 11.54368 ? 62  THR A C   1 
ATOM   464  O O   . THR A 1 62  ? -4.16786  13.29066 -8.44498  1.000 15.11978 ? 62  THR A O   1 
ATOM   465  C CB  . THR A 1 62  ? -6.87624  14.84451 -9.00205  1.000 16.12143 ? 62  THR A CB  1 
ATOM   466  O OG1 . THR A 1 62  ? -8.10585  15.20986 -8.37123  1.000 22.02661 ? 62  THR A OG1 1 
ATOM   467  C CG2 . THR A 1 62  ? -7.03539  15.05372 -10.51759 1.000 17.22465 ? 62  THR A CG2 1 
ATOM   468  N N   . ILE A 1 63  ? -5.06040  12.46619 -10.33600 1.000 10.89221 ? 63  ILE A N   1 
ATOM   469  C CA  . ILE A 1 63  ? -3.78449  12.22483 -10.99692 1.000 11.99236 ? 63  ILE A CA  1 
ATOM   470  C C   . ILE A 1 63  ? -3.90331  12.78271 -12.40588 1.000 13.79565 ? 63  ILE A C   1 
ATOM   471  O O   . ILE A 1 63  ? -4.80605  12.38650 -13.15532 1.000 12.43426 ? 63  ILE A O   1 
ATOM   472  C CB  . ILE A 1 63  ? -3.41930  10.73189 -11.05492 1.000 14.78291 ? 63  ILE A CB  1 
ATOM   473  C CG1 . ILE A 1 63  ? -3.29598  10.14446 -9.65135  1.000 15.69687 ? 63  ILE A CG1 1 
ATOM   474  C CG2 . ILE A 1 63  ? -2.10245  10.53798 -11.82443 1.000 15.74306 ? 63  ILE A CG2 1 
ATOM   475  C CD1 . ILE A 1 63  ? -2.99293  8.64852  -9.67292  1.000 17.23534 ? 63  ILE A CD1 1 
ATOM   476  N N   . PHE A 1 64  ? -3.02381  13.71451 -12.75899 1.000 11.12374 ? 64  PHE A N   1 
ATOM   477  C CA  . PHE A 1 64  ? -2.94825  14.22876 -14.12456 1.000 10.68052 ? 64  PHE A CA  1 
ATOM   478  C C   . PHE A 1 64  ? -1.62575  13.77931 -14.72426 1.000 10.14005 ? 64  PHE A C   1 
ATOM   479  O O   . PHE A 1 64  ? -0.56173  14.07809 -14.17580 1.000 10.13926 ? 64  PHE A O   1 
ATOM   480  C CB  . PHE A 1 64  ? -3.06419  15.75561 -14.16018 1.000 9.79112  ? 64  PHE A CB  1 
ATOM   481  C CG  . PHE A 1 64  ? -2.81926  16.35526 -15.53438 1.000 9.83255  ? 64  PHE A CG  1 
ATOM   482  C CD1 . PHE A 1 64  ? -3.37673  15.77949 -16.66314 1.000 10.84360 ? 64  PHE A CD1 1 
ATOM   483  C CD2 . PHE A 1 64  ? -2.04180  17.50540 -15.67882 1.000 10.95329 ? 64  PHE A CD2 1 
ATOM   484  C CE1 . PHE A 1 64  ? -3.15662  16.33934 -17.93971 1.000 9.09066  ? 64  PHE A CE1 1 
ATOM   485  C CE2 . PHE A 1 64  ? -1.81395  18.05828 -16.93366 1.000 10.58565 ? 64  PHE A CE2 1 
ATOM   486  C CZ  . PHE A 1 64  ? -2.37468  17.47209 -18.06685 1.000 9.88338  ? 64  PHE A CZ  1 
ATOM   487  N N   . VAL A 1 65  ? -1.68896  13.05069 -15.83594 1.000 9.19358  ? 65  VAL A N   1 
ATOM   488  C CA  . VAL A 1 65  ? -0.50354  12.60364 -16.55761 1.000 8.58142  ? 65  VAL A CA  1 
ATOM   489  C C   . VAL A 1 65  ? -0.40830  13.43971 -17.82826 1.000 8.69384  ? 65  VAL A C   1 
ATOM   490  O O   . VAL A 1 65  ? -1.28876  13.35966 -18.69196 1.000 10.50115 ? 65  VAL A O   1 
ATOM   491  C CB  . VAL A 1 65  ? -0.57805  11.10362 -16.89576 1.000 9.03989  ? 65  VAL A CB  1 
ATOM   492  C CG1 . VAL A 1 65  ? 0.65712   10.67457 -17.69595 1.000 11.63589 ? 65  VAL A CG1 1 
ATOM   493  C CG2 . VAL A 1 65  ? -0.69744  10.27389 -15.61283 1.000 13.41637 ? 65  VAL A CG2 1 
ATOM   494  N N   . HIS A 1 66  ? 0.65671   14.24298 -17.94102 1.000 8.63210  ? 66  HIS A N   1 
ATOM   495  C CA  . HIS A 1 66  ? 0.93955   15.04530 -19.13930 1.000 7.57051  ? 66  HIS A CA  1 
ATOM   496  C C   . HIS A 1 66  ? 2.10141   14.37976 -19.86294 1.000 8.43585  ? 66  HIS A C   1 
ATOM   497  O O   . HIS A 1 66  ? 3.25372   14.48521 -19.42989 1.000 9.99166  ? 66  HIS A O   1 
ATOM   498  C CB  . HIS A 1 66  ? 1.27636   16.48971 -18.78151 1.000 8.75388  ? 66  HIS A CB  1 
ATOM   499  C CG  . HIS A 1 66  ? 1.29930   17.41785 -19.95618 1.000 8.62342  ? 66  HIS A CG  1 
ATOM   500  N ND1 . HIS A 1 66  ? 1.74555   18.72072 -19.86403 1.000 9.63866  ? 66  HIS A ND1 1 
ATOM   501  C CD2 . HIS A 1 66  ? 0.91828   17.24043 -21.24193 1.000 12.93072 ? 66  HIS A CD2 1 
ATOM   502  C CE1 . HIS A 1 66  ? 1.64490   19.30268 -21.04602 1.000 12.13910 ? 66  HIS A CE1 1 
ATOM   503  N NE2 . HIS A 1 66  ? 1.13517   18.43034 -21.89868 1.000 11.79817 ? 66  HIS A NE2 1 
ATOM   504  N N   . GLY A 1 67  ? 1.79478   13.66807 -20.94749 1.000 9.90818  ? 67  GLY A N   1 
ATOM   505  C CA  . GLY A 1 67  ? 2.81378   12.95295 -21.69921 1.000 9.49783  ? 67  GLY A CA  1 
ATOM   506  C C   . GLY A 1 67  ? 3.34424   13.79832 -22.84035 1.000 9.26548  ? 67  GLY A C   1 
ATOM   507  O O   . GLY A 1 67  ? 2.57214   14.36307 -23.61685 1.000 9.29686  ? 67  GLY A O   1 
ATOM   508  N N   . LEU A 1 68  ? 4.66540   13.89334 -22.93503 1.000 8.55310  ? 68  LEU A N   1 
ATOM   509  C CA  . LEU A 1 68  ? 5.31599   14.68595 -23.97741 1.000 8.42008  ? 68  LEU A CA  1 
ATOM   510  C C   . LEU A 1 68  ? 6.03133   13.73713 -24.94192 1.000 11.90867 ? 68  LEU A C   1 
ATOM   511  O O   . LEU A 1 68  ? 6.98319   13.05454 -24.55742 1.000 11.65666 ? 68  LEU A O   1 
ATOM   512  C CB  . LEU A 1 68  ? 6.27087   15.69062 -23.34370 1.000 8.36275  ? 68  LEU A CB  1 
ATOM   513  C CG  . LEU A 1 68  ? 5.59738   16.60383 -22.31755 1.000 9.26345  ? 68  LEU A CG  1 
ATOM   514  C CD1 . LEU A 1 68  ? 6.64638   17.44208 -21.58875 1.000 10.29005 ? 68  LEU A CD1 1 
ATOM   515  C CD2 . LEU A 1 68  ? 4.58916   17.52524 -22.99310 1.000 12.29494 ? 68  LEU A CD2 1 
ATOM   516  N N   . HIS A 1 69  ? 5.56105   13.69756 -26.18957 1.000 10.86413 ? 69  HIS A N   1 
ATOM   517  C CA  . HIS A 1 69  ? 5.88415   12.66879 -27.17363 1.000 10.05172 ? 69  HIS A CA  1 
ATOM   518  C C   . HIS A 1 69  ? 6.48020   13.30526 -28.41310 1.000 11.41213 ? 69  HIS A C   1 
ATOM   519  O O   . HIS A 1 69  ? 6.26651   14.48914 -28.68671 1.000 10.39874 ? 69  HIS A O   1 
ATOM   520  C CB  . HIS A 1 69  ? 4.63574   11.90803 -27.65119 1.000 9.85054  ? 69  HIS A CB  1 
ATOM   521  C CG  . HIS A 1 69  ? 3.99601   11.03982 -26.62098 1.000 11.31580 ? 69  HIS A CG  1 
ATOM   522  N ND1 . HIS A 1 69  ? 2.77229   10.44072 -26.83161 1.000 14.94807 ? 69  HIS A ND1 1 
ATOM   523  C CD2 . HIS A 1 69  ? 4.42071   10.62247 -25.40902 1.000 13.84677 ? 69  HIS A CD2 1 
ATOM   524  C CE1 . HIS A 1 69  ? 2.45500   9.71816  -25.77083 1.000 17.20306 ? 69  HIS A CE1 1 
ATOM   525  N NE2 . HIS A 1 69  ? 3.43871   9.81297  -24.89357 1.000 13.64313 ? 69  HIS A NE2 1 
ATOM   526  N N   . ARG A 1 70  ? 7.18448   12.48591 -29.19002 1.000 11.09759 ? 70  ARG A N   1 
ATOM   527  C CA  . ARG A 1 70  ? 7.51655   12.84357 -30.56049 1.000 10.88500 ? 70  ARG A CA  1 
ATOM   528  C C   . ARG A 1 70  ? 6.27368   12.77528 -31.44285 1.000 10.74989 ? 70  ARG A C   1 
ATOM   529  O O   . ARG A 1 70  ? 5.43025   11.88776 -31.29596 1.000 12.09331 ? 70  ARG A O   1 
ATOM   530  C CB  . ARG A 1 70  ? 8.54112   11.86155 -31.12885 1.000 14.86695 ? 70  ARG A CB  1 
ATOM   531  C CG  . ARG A 1 70  ? 9.94353   12.04036 -30.64407 1.000 15.58855 ? 70  ARG A CG  1 
ATOM   532  C CD  . ARG A 1 70  ? 10.75772  10.82496 -31.04790 1.000 16.92669 ? 70  ARG A CD  1 
ATOM   533  N NE  . ARG A 1 70  ? 10.46579  9.69758  -30.16652 1.000 20.16266 ? 70  ARG A NE  1 
ATOM   534  C CZ  . ARG A 1 70  ? 10.93165  8.46899  -30.34398 1.000 33.01016 ? 70  ARG A CZ  1 
ATOM   535  N NH1 . ARG A 1 70  ? 11.70034  8.16771  -31.37531 1.000 29.67995 ? 70  ARG A NH1 1 
ATOM   536  N NH2 . ARG A 1 70  ? 10.62544  7.52268  -29.45801 1.000 26.36138 ? 70  ARG A NH2 1 
ATOM   537  N N   . GLU A 1 71  ? 6.21153   13.67219 -32.42639 1.000 11.12501 ? 71  GLU A N   1 
ATOM   538  C CA  . GLU A 1 71  ? 5.23423   13.52903 -33.49776 1.000 10.94326 ? 71  GLU A CA  1 
ATOM   539  C C   . GLU A 1 71  ? 5.49060   12.25384 -34.29172 1.000 13.68784 ? 71  GLU A C   1 
ATOM   540  O O   . GLU A 1 71  ? 6.62738   11.78207 -34.40251 1.000 13.18139 ? 71  GLU A O   1 
ATOM   541  C CB  . GLU A 1 71  ? 5.30956   14.71372 -34.46126 1.000 13.53909 ? 71  GLU A CB  1 
ATOM   542  C CG  . GLU A 1 71  ? 4.80743   16.01719 -33.90508 1.000 14.61393 ? 71  GLU A CG  1 
ATOM   543  C CD  . GLU A 1 71  ? 5.03789   17.17415 -34.86041 1.000 17.93184 ? 71  GLU A CD  1 
ATOM   544  O OE1 . GLU A 1 71  ? 5.77060   16.99428 -35.86078 1.000 16.32696 ? 71  GLU A OE1 1 
ATOM   545  O OE2 . GLU A 1 71  ? 4.48707   18.26138 -34.60170 1.000 21.72611 ? 71  GLU A OE2 1 
ATOM   546  N N   . GLY A 1 72  ? 4.42587   11.72731 -34.89031 1.000 11.49857 ? 72  GLY A N   1 
ATOM   547  C CA  . GLY A 1 72  ? 4.57834   10.60150 -35.80208 1.000 11.81863 ? 72  GLY A CA  1 
ATOM   548  C C   . GLY A 1 72  ? 3.69910   9.38771  -35.56440 1.000 12.90451 ? 72  GLY A C   1 
ATOM   549  O O   . GLY A 1 72  ? 3.56767   8.54994  -36.45613 1.000 13.82665 ? 72  GLY A O   1 
ATOM   550  N N   . ARG A 1 73  ? 3.09070   9.25847  -34.39075 1.000 12.93825 ? 73  ARG A N   1 
ATOM   551  C CA  . ARG A 1 73  ? 2.27338   8.08279  -34.14493 1.000 13.73021 ? 73  ARG A CA  1 
ATOM   552  C C   . ARG A 1 73  ? 0.82049   8.34306  -34.53300 1.000 11.12646 ? 73  ARG A C   1 
ATOM   553  O O   . ARG A 1 73  ? 0.36576   9.48408  -34.65965 1.000 13.13159 ? 73  ARG A O   1 
ATOM   554  C CB  . ARG A 1 73  ? 2.37565   7.64336  -32.68169 1.000 15.53757 ? 73  ARG A CB  1 
ATOM   555  C CG  . ARG A 1 73  ? 3.81796   7.31416  -32.29652 1.000 17.75102 ? 73  ARG A CG  1 
ATOM   556  C CD  . ARG A 1 73  ? 3.95145   6.38639  -31.11676 1.000 20.08989 ? 73  ARG A CD  1 
ATOM   557  N NE  . ARG A 1 73  ? 5.36510   6.22598  -30.80236 1.000 23.07510 ? 73  ARG A NE  1 
ATOM   558  C CZ  . ARG A 1 73  ? 6.04670   7.04802  -30.01804 1.000 24.81801 ? 73  ARG A CZ  1 
ATOM   559  N NH1 . ARG A 1 73  ? 5.47087   8.10584  -29.45408 1.000 22.98365 ? 73  ARG A NH1 1 
ATOM   560  N NH2 . ARG A 1 73  ? 7.34018   6.81818  -29.80966 1.000 29.17384 ? 73  ARG A NH2 1 
ATOM   561  N N   . SER A 1 74  ? 0.10637   7.25489  -34.76003 1.000 13.13529 ? 74  SER A N   1 
ATOM   562  C CA  . SER A 1 74  ? -1.27513  7.32798  -35.20152 1.000 10.27417 ? 74  SER A CA  1 
ATOM   563  C C   . SER A 1 74  ? -2.20433  7.68305  -34.04665 1.000 10.25446 ? 74  SER A C   1 
ATOM   564  O O   . SER A 1 74  ? -1.89193  7.48166  -32.86989 1.000 12.08348 ? 74  SER A O   1 
ATOM   565  C CB  . SER A 1 74  ? -1.67767  5.99797  -35.84159 1.000 13.06610 ? 74  SER A CB  1 
ATOM   566  O OG  . SER A 1 74  ? -1.85344  5.00490  -34.83533 1.000 12.87235 ? 74  SER A OG  1 
ATOM   567  N N   . ALA A 1 75  ? -3.35306  8.26300  -34.40474 1.000 9.96355  ? 75  ALA A N   1 
ATOM   568  C CA  . ALA A 1 75  ? -4.38683  8.52001  -33.41004 1.000 11.30498 ? 75  ALA A CA  1 
ATOM   569  C C   . ALA A 1 75  ? -4.83803  7.22642  -32.74918 1.000 12.50962 ? 75  ALA A C   1 
ATOM   570  O O   . ALA A 1 75  ? -5.09294  7.19445  -31.54140 1.000 11.24966 ? 75  ALA A O   1 
ATOM   571  C CB  . ALA A 1 75  ? -5.57401  9.22689  -34.06682 1.000 12.37133 ? 75  ALA A CB  1 
ATOM   572  N N   . ASP A 1 76  ? -4.94869  6.15156  -33.53281 1.000 12.28014 ? 76  ASP A N   1 
ATOM   573  C CA  . ASP A 1 76  ? -5.29983  4.84516  -32.98367 1.000 12.20430 ? 76  ASP A CA  1 
ATOM   574  C C   . ASP A 1 76  ? -4.34783  4.44513  -31.85853 1.000 13.49362 ? 76  ASP A C   1 
ATOM   575  O O   . ASP A 1 76  ? -4.77462  4.11095  -30.74683 1.000 13.77187 ? 76  ASP A O   1 
ATOM   576  C CB  . ASP A 1 76  ? -5.25322  3.80543  -34.10769 1.000 14.52701 ? 76  ASP A CB  1 
ATOM   577  C CG  . ASP A 1 76  ? -5.67073  2.42379  -33.65157 1.000 22.60435 ? 76  ASP A CG  1 
ATOM   578  O OD1 . ASP A 1 76  ? -6.41176  2.31895  -32.65926 1.000 28.66796 ? 76  ASP A OD1 1 
ATOM   579  O OD2 . ASP A 1 76  ? -5.22175  1.43783  -34.26519 1.000 33.47684 ? 76  ASP A OD2 1 
ATOM   580  N N   . LEU A 1 77  ? -3.04551  4.46467  -32.14072 1.000 12.89803 ? 77  LEU A N   1 
ATOM   581  C CA  . LEU A 1 77  ? -2.06392  4.04014  -31.15041 1.000 13.18712 ? 77  LEU A CA  1 
ATOM   582  C C   . LEU A 1 77  ? -2.05128  4.96106  -29.93783 1.000 13.69798 ? 77  LEU A C   1 
ATOM   583  O O   . LEU A 1 77  ? -1.99137  4.49133  -28.79570 1.000 13.77241 ? 77  LEU A O   1 
ATOM   584  C CB  . LEU A 1 77  ? -0.68414  3.97258  -31.79711 1.000 14.17311 ? 77  LEU A CB  1 
ATOM   585  C CG  . LEU A 1 77  ? 0.48288   3.29233  -31.07502 1.000 19.22617 ? 77  LEU A CG  1 
ATOM   586  C CD1 . LEU A 1 77  ? 1.16157   4.25150  -30.08830 1.000 25.12229 ? 77  LEU A CD1 1 
ATOM   587  C CD2 . LEU A 1 77  ? 0.02669   2.02303  -30.39652 1.000 18.48926 ? 77  LEU A CD2 1 
ATOM   588  N N   . LYS A 1 78  ? -2.10384  6.27610  -30.15384 1.000 10.42163 ? 78  LYS A N   1 
ATOM   589  C CA  . LYS A 1 78  ? -2.11038  7.17191  -29.00569 1.000 11.99310 ? 78  LYS A CA  1 
ATOM   590  C C   . LYS A 1 78  ? -3.32913  6.91796  -28.12268 1.000 10.83458 ? 78  LYS A C   1 
ATOM   591  O O   . LYS A 1 78  ? -3.23889  7.01601  -26.89454 1.000 11.24517 ? 78  LYS A O   1 
ATOM   592  C CB  . LYS A 1 78  ? -2.05651  8.62530  -29.48265 1.000 13.45082 ? 78  LYS A CB  1 
ATOM   593  C CG  . LYS A 1 78  ? -0.67006  9.02264  -29.99078 1.000 13.48785 ? 78  LYS A CG  1 
ATOM   594  C CD  . LYS A 1 78  ? -0.64713  10.47395 -30.50188 1.000 11.68429 ? 78  LYS A CD  1 
ATOM   595  C CE  . LYS A 1 78  ? -1.39264  10.58944 -31.84135 1.000 14.22329 ? 78  LYS A CE  1 
ATOM   596  N NZ  . LYS A 1 78  ? -1.36063  11.98516 -32.38002 1.000 13.94266 ? 78  LYS A NZ  1 
ATOM   597  N N   . GLY A 1 79  ? -4.46713  6.55682  -28.71790 1.000 12.34028 ? 79  GLY A N   1 
ATOM   598  C CA  . GLY A 1 79  ? -5.63865  6.26086  -27.91127 1.000 10.76793 ? 79  GLY A CA  1 
ATOM   599  C C   . GLY A 1 79  ? -5.46922  4.98963  -27.10237 1.000 13.60147 ? 79  GLY A C   1 
ATOM   600  O O   . GLY A 1 79  ? -5.83078  4.94111  -25.92397 1.000 12.95864 ? 79  GLY A O   1 
ATOM   601  N N   . GLN A 1 80  ? -4.92353  3.94411  -27.72828 1.000 12.68126 ? 80  GLN A N   1 
ATOM   602  C CA  . GLN A 1 80  ? -4.59489  2.72437  -26.99461 1.000 12.74966 ? 80  GLN A CA  1 
ATOM   603  C C   . GLN A 1 80  ? -3.66316  3.02172  -25.83688 1.000 13.03558 ? 80  GLN A C   1 
ATOM   604  O O   . GLN A 1 80  ? -3.82767  2.48211  -24.73736 1.000 14.06759 ? 80  GLN A O   1 
ATOM   605  C CB  . GLN A 1 80  ? -3.93521  1.71138  -27.92782 1.000 13.81320 ? 80  GLN A CB  1 
ATOM   606  C CG  . GLN A 1 80  ? -4.79669  1.25821  -29.07439 1.000 15.49200 ? 80  GLN A CG  1 
ATOM   607  C CD  . GLN A 1 80  ? -4.03836  0.32430  -30.00313 1.000 20.49143 ? 80  GLN A CD  1 
ATOM   608  O OE1 . GLN A 1 80  ? -3.26568  -0.52532 -29.55297 1.000 23.94696 ? 80  GLN A OE1 1 
ATOM   609  N NE2 . GLN A 1 80  ? -4.22944  0.50311  -31.31087 1.000 25.61875 ? 80  GLN A NE2 1 
ATOM   610  N N   . LEU A 1 81  ? -2.65613  3.85660  -26.08086 1.000 11.93593 ? 81  LEU A N   1 
ATOM   611  C CA  . LEU A 1 81  ? -1.66298  4.15475  -25.05667 1.000 11.99384 ? 81  LEU A CA  1 
ATOM   612  C C   . LEU A 1 81  ? -2.27742  4.95437  -23.92062 1.000 11.84563 ? 81  LEU A C   1 
ATOM   613  O O   . LEU A 1 81  ? -2.01432  4.66920  -22.74758 1.000 13.93884 ? 81  LEU A O   1 
ATOM   614  C CB  . LEU A 1 81  ? -0.48745  4.90644  -25.68504 1.000 12.58683 ? 81  LEU A CB  1 
ATOM   615  C CG  . LEU A 1 81  ? 0.69139   5.32995  -24.80705 1.000 9.17937  ? 81  LEU A CG  1 
ATOM   616  C CD1 . LEU A 1 81  ? 1.25520   4.14932  -23.99961 1.000 12.79875 ? 81  LEU A CD1 1 
ATOM   617  C CD2 . LEU A 1 81  ? 1.76122   5.95829  -25.67180 1.000 14.15368 ? 81  LEU A CD2 1 
ATOM   618  N N   . ALA A 1 82  ? -3.11256  5.95074  -24.24280 1.000 11.48966 ? 82  ALA A N   1 
ATOM   619  C CA  . ALA A 1 82  ? -3.76761  6.70752  -23.18321 1.000 11.01019 ? 82  ALA A CA  1 
ATOM   620  C C   . ALA A 1 82  ? -4.69568  5.81562  -22.36598 1.000 12.71649 ? 82  ALA A C   1 
ATOM   621  O O   . ALA A 1 82  ? -4.73799  5.91897  -21.13658 1.000 12.83312 ? 82  ALA A O   1 
ATOM   622  C CB  . ALA A 1 82  ? -4.54491  7.88891  -23.76429 1.000 12.29844 ? 82  ALA A CB  1 
ATOM   623  N N   . GLN A 1 83  ? -5.45148  4.93642  -23.02892 1.000 11.24333 ? 83  GLN A N   1 
ATOM   624  C CA  . GLN A 1 83  ? -6.33346  4.04092  -22.28745 1.000 14.43163 ? 83  GLN A CA  1 
ATOM   625  C C   . GLN A 1 83  ? -5.53137  3.10829  -21.39243 1.000 13.81947 ? 83  GLN A C   1 
ATOM   626  O O   . GLN A 1 83  ? -5.90698  2.86962  -20.23389 1.000 13.20497 ? 83  GLN A O   1 
ATOM   627  C CB  . GLN A 1 83  ? -7.21286  3.23743  -23.24806 1.000 13.92931 ? 83  GLN A CB  1 
ATOM   628  C CG  . GLN A 1 83  ? -8.25340  2.39089  -22.51199 1.000 14.66137 ? 83  GLN A CG  1 
ATOM   629  C CD  . GLN A 1 83  ? -9.23013  3.25407  -21.73599 1.000 19.24363 ? 83  GLN A CD  1 
ATOM   630  O OE1 . GLN A 1 83  ? -9.95428  4.05147  -22.32081 1.000 18.48794 ? 83  GLN A OE1 1 
ATOM   631  N NE2 . GLN A 1 83  ? -9.24126  3.11135  -20.40995 1.000 19.36278 ? 83  GLN A NE2 1 
ATOM   632  N N   . ARG A 1 84  ? -4.42503  2.56918  -21.91093 1.000 12.55644 ? 84  ARG A N   1 
ATOM   633  C CA  . ARG A 1 84  ? -3.62025  1.65738  -21.10362 1.000 13.18512 ? 84  ARG A CA  1 
ATOM   634  C C   . ARG A 1 84  ? -3.00062  2.37095  -19.91100 1.000 16.24138 ? 84  ARG A C   1 
ATOM   635  O O   . ARG A 1 84  ? -2.90217  1.78887  -18.82186 1.000 17.81745 ? 84  ARG A O   1 
ATOM   636  C CB  . ARG A 1 84  ? -2.55022  0.98631  -21.96536 1.000 16.41438 ? 84  ARG A CB  1 
ATOM   637  C CG  . ARG A 1 84  ? -1.57165  0.20199  -21.12453 1.000 21.60603 ? 84  ARG A CG  1 
ATOM   638  C CD  . ARG A 1 84  ? -0.73196  -0.77024 -21.92668 1.000 21.46380 ? 84  ARG A CD  1 
ATOM   639  N NE  . ARG A 1 84  ? 0.07899   -1.56642 -21.01437 1.000 30.22989 ? 84  ARG A NE  1 
ATOM   640  C CZ  . ARG A 1 84  ? 1.04252   -2.39343 -21.39287 1.000 26.66228 ? 84  ARG A CZ  1 
ATOM   641  N NH1 . ARG A 1 84  ? 1.26202   -2.65946 -22.67294 1.000 30.19485 ? 84  ARG A NH1 1 
ATOM   642  N NH2 . ARG A 1 84  ? 1.82616   -2.93878 -20.46805 1.000 24.66753 ? 84  ARG A NH2 1 
ATOM   643  N N   . ILE A 1 85  ? -2.62095  3.64157  -20.07390 1.000 13.70497 ? 85  ILE A N   1 
ATOM   644  C CA  . ILE A 1 85  ? -2.12756  4.40022  -18.93101 1.000 12.55985 ? 85  ILE A CA  1 
ATOM   645  C C   . ILE A 1 85  ? -3.22664  4.55950  -17.88755 1.000 12.76264 ? 85  ILE A C   1 
ATOM   646  O O   . ILE A 1 85  ? -2.99629  4.34607  -16.68754 1.000 13.03615 ? 85  ILE A O   1 
ATOM   647  C CB  . ILE A 1 85  ? -1.54839  5.75289  -19.39464 1.000 11.91862 ? 85  ILE A CB  1 
ATOM   648  C CG1 . ILE A 1 85  ? -0.17366  5.53548  -20.02972 1.000 13.26813 ? 85  ILE A CG1 1 
ATOM   649  C CG2 . ILE A 1 85  ? -1.41161  6.70891  -18.21606 1.000 14.30235 ? 85  ILE A CG2 1 
ATOM   650  C CD1 . ILE A 1 85  ? 0.39853   6.78288  -20.69984 1.000 13.11730 ? 85  ILE A CD1 1 
ATOM   651  N N   . VAL A 1 86  ? -4.44849  4.88521  -18.31517 1.000 11.95847 ? 86  VAL A N   1 
ATOM   652  C CA  . VAL A 1 86  ? -5.53421  5.02267  -17.34763 1.000 13.65584 ? 86  VAL A CA  1 
ATOM   653  C C   . VAL A 1 86  ? -5.74588  3.70236  -16.61656 1.000 15.80687 ? 86  VAL A C   1 
ATOM   654  O O   . VAL A 1 86  ? -5.80351  3.65884  -15.38086 1.000 16.46340 ? 86  VAL A O   1 
ATOM   655  C CB  . VAL A 1 86  ? -6.82451  5.50785  -18.03513 1.000 14.38090 ? 86  VAL A CB  1 
ATOM   656  C CG1 . VAL A 1 86  ? -8.00514  5.45818  -17.06643 1.000 14.66648 ? 86  VAL A CG1 1 
ATOM   657  C CG2 . VAL A 1 86  ? -6.64646  6.90851  -18.60329 1.000 14.58664 ? 86  VAL A CG2 1 
ATOM   658  N N   . ASP A 1 87  ? -5.83865  2.60228  -17.36878 1.000 15.65540 ? 87  ASP A N   1 
ATOM   659  C CA  . ASP A 1 87  ? -6.12188  1.30855  -16.74224 1.000 15.76557 ? 87  ASP A CA  1 
ATOM   660  C C   . ASP A 1 87  ? -4.99713  0.88111  -15.80896 1.000 18.58533 ? 87  ASP A C   1 
ATOM   661  O O   . ASP A 1 87  ? -5.24752  0.44840  -14.67729 1.000 17.62302 ? 87  ASP A O   1 
ATOM   662  C CB  . ASP A 1 87  ? -6.35702  0.23564  -17.80827 1.000 17.22730 ? 87  ASP A CB  1 
ATOM   663  C CG  . ASP A 1 87  ? -7.61453  0.47823  -18.61351 1.000 21.86596 ? 87  ASP A CG  1 
ATOM   664  O OD1 . ASP A 1 87  ? -8.53099  1.14667  -18.09095 1.000 25.79621 ? 87  ASP A OD1 1 
ATOM   665  O OD2 . ASP A 1 87  ? -7.70588  -0.03420 -19.74980 1.000 21.16498 ? 87  ASP A OD2 1 
ATOM   666  N N   . ASP A 1 88  ? -3.75325  0.97599  -16.27131 1.000 14.36451 ? 88  ASP A N   1 
ATOM   667  C CA  . ASP A 1 88  ? -2.63779  0.45285  -15.49004 1.000 14.80063 ? 88  ASP A CA  1 
ATOM   668  C C   . ASP A 1 88  ? -2.22558  1.37031  -14.34574 1.000 15.82639 ? 88  ASP A C   1 
ATOM   669  O O   . ASP A 1 88  ? -1.72375  0.88269  -13.33006 1.000 18.31831 ? 88  ASP A O   1 
ATOM   670  C CB  . ASP A 1 88  ? -1.45023  0.17087  -16.40189 1.000 19.50316 ? 88  ASP A CB  1 
ATOM   671  C CG  . ASP A 1 88  ? -1.71822  -0.97569 -17.35829 1.000 17.29374 ? 88  ASP A CG  1 
ATOM   672  O OD1 . ASP A 1 88  ? -2.81854  -1.56830 -17.29128 1.000 21.00894 ? 88  ASP A OD1 1 
ATOM   673  O OD2 . ASP A 1 88  ? -0.83223  -1.26512 -18.17827 1.000 20.50949 ? 88  ASP A OD2 1 
ATOM   674  N N   . VAL A 1 89  ? -2.41589  2.68781  -14.46542 1.000 13.56251 ? 89  VAL A N   1 
ATOM   675  C CA  . VAL A 1 89  ? -2.14838  3.55024  -13.31723 1.000 16.44102 ? 89  VAL A CA  1 
ATOM   676  C C   . VAL A 1 89  ? -3.22495  3.36270  -12.25200 1.000 18.05458 ? 89  VAL A C   1 
ATOM   677  O O   . VAL A 1 89  ? -2.93541  3.39706  -11.04681 1.000 15.95793 ? 89  VAL A O   1 
ATOM   678  C CB  . VAL A 1 89  ? -2.01824  5.02188  -13.75983 1.000 14.98292 ? 89  VAL A CB  1 
ATOM   679  C CG1 . VAL A 1 89  ? -2.03579  5.95277  -12.56150 1.000 14.67882 ? 89  VAL A CG1 1 
ATOM   680  C CG2 . VAL A 1 89  ? -0.72665  5.21069  -14.52251 1.000 15.97254 ? 89  VAL A CG2 1 
ATOM   681  N N   . SER A 1 90  ? -4.47692  3.15574  -12.67614 1.000 15.42209 ? 90  SER A N   1 
ATOM   682  C CA  . SER A 1 90  ? -5.55217  2.88281  -11.72606 1.000 14.70722 ? 90  SER A CA  1 
ATOM   683  C C   . SER A 1 90  ? -5.22277  1.68253  -10.85354 1.000 19.14366 ? 90  SER A C   1 
ATOM   684  O O   . SER A 1 90  ? -5.43770  1.71498  -9.63631  1.000 18.74318 ? 90  SER A O   1 
ATOM   685  C CB  . SER A 1 90  ? -6.86639  2.64836  -12.46352 1.000 18.87301 ? 90  SER A CB  1 
ATOM   686  O OG  . SER A 1 90  ? -7.89253  2.29886  -11.54445 1.000 18.47273 ? 90  SER A OG  1 
ATOM   687  N N   . VAL A 1 91  ? -4.69407  0.62002  -11.46077 1.000 17.01443 ? 91  VAL A N   1 
ATOM   688  C CA  . VAL A 1 91  ? -4.28092  -0.55710 -10.69644 1.000 20.00011 ? 91  VAL A CA  1 
ATOM   689  C C   . VAL A 1 91  ? -3.07247  -0.23796 -9.81669  1.000 19.74376 ? 91  VAL A C   1 
ATOM   690  O O   . VAL A 1 91  ? -3.06624  -0.53278 -8.61236  1.000 19.84215 ? 91  VAL A O   1 
ATOM   691  C CB  . VAL A 1 91  ? -3.99437  -1.73272 -11.64857 1.000 19.61392 ? 91  VAL A CB  1 
ATOM   692  C CG1 . VAL A 1 91  ? -3.34371  -2.89226 -10.88617 1.000 24.41681 ? 91  VAL A CG1 1 
ATOM   693  C CG2 . VAL A 1 91  ? -5.27344  -2.20494 -12.28183 1.000 20.34907 ? 91  VAL A CG2 1 
ATOM   694  N N   . ALA A 1 92  ? -2.03214  0.36712  -10.40437 1.000 16.62602 ? 92  ALA A N   1 
ATOM   695  C CA  . ALA A 1 92  ? -0.78255  0.59038  -9.67869  1.000 18.14670 ? 92  ALA A CA  1 
ATOM   696  C C   . ALA A 1 92  ? -0.97260  1.53073  -8.49688  1.000 20.75816 ? 92  ALA A C   1 
ATOM   697  O O   . ALA A 1 92  ? -0.35340  1.34566  -7.43854  1.000 21.06656 ? 92  ALA A O   1 
ATOM   698  C CB  . ALA A 1 92  ? 0.28583   1.13975  -10.62336 1.000 17.05597 ? 92  ALA A CB  1 
ATOM   699  N N   . ALA A 1 93  ? -1.81325  2.55194  -8.65397  1.000 17.62624 ? 93  ALA A N   1 
ATOM   700  C CA  . ALA A 1 93  ? -2.04366  3.52986  -7.60096  1.000 16.97471 ? 93  ALA A CA  1 
ATOM   701  C C   . ALA A 1 93  ? -3.24212  3.19725  -6.71945  1.000 20.35365 ? 93  ALA A C   1 
ATOM   702  O O   . ALA A 1 93  ? -3.49090  3.91672  -5.74872  1.000 20.68797 ? 93  ALA A O   1 
ATOM   703  C CB  . ALA A 1 93  ? -2.23155  4.92736  -8.21007  1.000 17.64787 ? 93  ALA A CB  1 
ATOM   704  N N   . GLU A 1 94  ? -3.97443  2.12821  -7.01949  1.000 19.86989 ? 94  GLU A N   1 
ATOM   705  C CA  . GLU A 1 94  ? -5.20250  1.78631  -6.30219  1.000 22.56240 ? 94  GLU A CA  1 
ATOM   706  C C   . GLU A 1 94  ? -6.15678  2.97555  -6.26088  1.000 24.21255 ? 94  GLU A C   1 
ATOM   707  O O   . GLU A 1 94  ? -6.64388  3.39843  -5.21029  1.000 22.46178 ? 94  GLU A O   1 
ATOM   708  C CB  . GLU A 1 94  ? -4.90804  1.26546  -4.89480  1.000 24.40946 ? 94  GLU A CB  1 
ATOM   709  C CG  . GLU A 1 94  ? -4.41048  -0.16788 -4.88920  1.000 33.73001 ? 94  GLU A CG  1 
ATOM   710  C CD  . GLU A 1 94  ? -3.57006  -0.50041 -3.67653  1.000 38.91766 ? 94  GLU A CD  1 
ATOM   711  O OE1 . GLU A 1 94  ? -4.01631  -1.35885 -2.88651  1.000 44.80420 ? 94  GLU A OE1 1 
ATOM   712  O OE2 . GLU A 1 94  ? -2.47572  0.08021  -3.50929  1.000 43.97357 ? 94  GLU A OE2 1 
ATOM   713  N N   . ILE A 1 95  ? -6.43275  3.50908  -7.43947  1.000 24.82227 ? 95  ILE A N   1 
ATOM   714  C CA  . ILE A 1 95  ? -7.22468  4.71492  -7.59355  1.000 20.68468 ? 95  ILE A CA  1 
ATOM   715  C C   . ILE A 1 95  ? -8.28173  4.47727  -8.65751  1.000 22.38495 ? 95  ILE A C   1 
ATOM   716  O O   . ILE A 1 95  ? -8.01712  3.81167  -9.66269  1.000 24.06239 ? 95  ILE A O   1 
ATOM   717  C CB  . ILE A 1 95  ? -6.32856  5.89765  -7.97267  1.000 22.08928 ? 95  ILE A CB  1 
ATOM   718  C CG1 . ILE A 1 95  ? -7.13102  7.17340  -7.95929  1.000 23.01781 ? 95  ILE A CG1 1 
ATOM   719  C CG2 . ILE A 1 95  ? -5.63517  5.65490  -9.31406  1.000 23.17593 ? 95  ILE A CG2 1 
ATOM   720  C CD1 . ILE A 1 95  ? -6.24972  8.27809  -7.99139  1.000 20.34233 ? 95  ILE A CD1 1 
ATOM   721  N N   . ASP A 1 96  ? -9.47836  5.01430  -8.44682  1.000 17.44742 ? 96  ASP A N   1 
ATOM   722  C CA  . ASP A 1 96  ? -10.50785 4.77436  -9.43878  1.000 14.99772 ? 96  ASP A CA  1 
ATOM   723  C C   . ASP A 1 96  ? -10.21250 5.60690  -10.67993 1.000 17.08612 ? 96  ASP A C   1 
ATOM   724  O O   . ASP A 1 96  ? -9.69171  6.72563  -10.59727 1.000 14.96172 ? 96  ASP A O   1 
ATOM   725  C CB  . ASP A 1 96  ? -11.89271 5.12978  -8.91620  1.000 17.46649 ? 96  ASP A CB  1 
ATOM   726  C CG  . ASP A 1 96  ? -12.97301 4.84437  -9.94709  1.000 29.76048 ? 96  ASP A CG  1 
ATOM   727  O OD1 . ASP A 1 96  ? -13.24150 3.64730  -10.19086 1.000 37.61010 ? 96  ASP A OD1 1 
ATOM   728  O OD2 . ASP A 1 96  ? -13.50210 5.77829  -10.57407 1.000 22.90722 ? 96  ASP A OD2 1 
ATOM   729  N N   . ARG A 1 97  ? -10.55821 5.04907  -11.84072 1.000 17.12072 ? 97  ARG A N   1 
ATOM   730  C CA  . ARG A 1 97  ? -10.24008 5.71545  -13.09597 1.000 15.02913 ? 97  ARG A CA  1 
ATOM   731  C C   . ARG A 1 97  ? -10.86418 7.09468  -13.22350 1.000 16.50379 ? 97  ARG A C   1 
ATOM   732  O O   . ARG A 1 97  ? -10.36797 7.88581  -14.02692 1.000 15.05293 ? 97  ARG A O   1 
ATOM   733  C CB  . ARG A 1 97  ? -10.64901 4.85452  -14.29077 1.000 17.16115 ? 97  ARG A CB  1 
ATOM   734  C CG  . ARG A 1 97  ? -9.91324  3.54570  -14.39537 1.000 18.88336 ? 97  ARG A CG  1 
ATOM   735  C CD  . ARG A 1 97  ? -10.65598 2.56071  -15.30284 1.000 22.21964 ? 97  ARG A CD  1 
ATOM   736  N NE  . ARG A 1 97  ? -9.91601  1.30837  -15.39046 1.000 33.30302 ? 97  ARG A NE  1 
ATOM   737  C CZ  . ARG A 1 97  ? -9.95545  0.34829  -14.47722 1.000 38.67236 ? 97  ARG A CZ  1 
ATOM   738  N NH1 . ARG A 1 97  ? -10.71515 0.45299  -13.39702 1.000 36.96986 ? 97  ARG A NH1 1 
ATOM   739  N NH2 . ARG A 1 97  ? -9.19916  -0.73543 -14.64290 1.000 38.23097 ? 97  ARG A NH2 1 
ATOM   740  N N   . LYS A 1 98  ? -11.91008 7.41600  -12.44389 1.000 14.09486 ? 98  LYS A N   1 
ATOM   741  C CA  . LYS A 1 98  ? -12.55084 8.72659  -12.56297 1.000 15.52872 ? 98  LYS A CA  1 
ATOM   742  C C   . LYS A 1 98  ? -11.62658 9.82928  -12.09318 1.000 14.46875 ? 98  LYS A C   1 
ATOM   743  O O   . LYS A 1 98  ? -11.90162 11.00891 -12.34275 1.000 13.45539 ? 98  LYS A O   1 
ATOM   744  C CB  . LYS A 1 98  ? -13.81853 8.86308  -11.70870 1.000 15.84624 ? 98  LYS A CB  1 
ATOM   745  C CG  . LYS A 1 98  ? -13.59647 8.63055  -10.21000 1.000 19.46427 ? 98  LYS A CG  1 
ATOM   746  C CD  . LYS A 1 98  ? -14.92330 8.61815  -9.44032  1.000 20.53304 ? 98  LYS A CD  1 
ATOM   747  C CE  . LYS A 1 98  ? -14.73286 8.27862  -7.96244  1.000 29.41070 ? 98  LYS A CE  1 
ATOM   748  N NZ  . LYS A 1 98  ? -15.59658 7.14386  -7.51012  1.000 34.09721 ? 98  LYS A NZ  1 
ATOM   749  N N   . HIS A 1 99  ? -10.57635 9.47223  -11.36529 1.000 14.06578 ? 99  HIS A N   1 
ATOM   750  C CA  . HIS A 1 99  ? -9.61524  10.43561 -10.86159 1.000 12.55762 ? 99  HIS A CA  1 
ATOM   751  C C   . HIS A 1 99  ? -8.44788  10.67208 -11.80662 1.000 11.32829 ? 99  HIS A C   1 
ATOM   752  O O   . HIS A 1 99  ? -7.56246  11.46354 -11.46561 1.000 13.02219 ? 99  HIS A O   1 
ATOM   753  C CB  . HIS A 1 99  ? -9.05142  9.97798  -9.50780  1.000 16.28312 ? 99  HIS A CB  1 
ATOM   754  C CG  . HIS A 1 99  ? -10.05355 9.95929  -8.40068  1.000 17.67155 ? 99  HIS A CG  1 
ATOM   755  N ND1 . HIS A 1 99  ? -10.67933 11.09855 -7.94219  1.000 20.03250 ? 99  HIS A ND1 1 
ATOM   756  C CD2 . HIS A 1 99  ? -10.50367 8.94368  -7.62325  1.000 21.20803 ? 99  HIS A CD2 1 
ATOM   757  C CE1 . HIS A 1 99  ? -11.49365 10.78112 -6.95046  1.000 22.14070 ? 99  HIS A CE1 1 
ATOM   758  N NE2 . HIS A 1 99  ? -11.40420 9.47909  -6.73686  1.000 20.04560 ? 99  HIS A NE2 1 
ATOM   759  N N   . ILE A 1 100 ? -8.40580  10.01752 -12.97112 1.000 10.40907 ? 100 ILE A N   1 
ATOM   760  C CA  . ILE A 1 100 ? -7.20396  10.00131 -13.80663 1.000 10.09469 ? 100 ILE A CA  1 
ATOM   761  C C   . ILE A 1 100 ? -7.43584  10.81267 -15.08184 1.000 9.46706  ? 100 ILE A C   1 
ATOM   762  O O   . ILE A 1 100 ? -8.36076  10.53334 -15.85592 1.000 11.45490 ? 100 ILE A O   1 
ATOM   763  C CB  . ILE A 1 100 ? -6.77048  8.56584  -14.14140 1.000 13.89001 ? 100 ILE A CB  1 
ATOM   764  C CG1 . ILE A 1 100 ? -6.51775  7.77874  -12.83956 1.000 14.64779 ? 100 ILE A CG1 1 
ATOM   765  C CG2 . ILE A 1 100 ? -5.52819  8.58963  -15.00761 1.000 11.80768 ? 100 ILE A CG2 1 
ATOM   766  C CD1 . ILE A 1 100 ? -6.05427  6.34276  -13.04637 1.000 15.16302 ? 100 ILE A CD1 1 
ATOM   767  N N   . TRP A 1 101 ? -6.57139  11.79795 -15.31272 1.000 10.11929 ? 101 TRP A N   1 
ATOM   768  C CA  . TRP A 1 101 ? -6.58641  12.60455 -16.52433 1.000 9.14759  ? 101 TRP A CA  1 
ATOM   769  C C   . TRP A 1 101 ? -5.27798  12.36068 -17.26827 1.000 9.24521  ? 101 TRP A C   1 
ATOM   770  O O   . TRP A 1 101 ? -4.22454  12.27369 -16.64514 1.000 10.20037 ? 101 TRP A O   1 
ATOM   771  C CB  . TRP A 1 101 ? -6.74604  14.09415 -16.18995 1.000 11.86878 ? 101 TRP A CB  1 
ATOM   772  C CG  . TRP A 1 101 ? -7.98972  14.46270 -15.41637 1.000 9.50892  ? 101 TRP A CG  1 
ATOM   773  C CD1 . TRP A 1 101 ? -8.57056  13.78324 -14.36738 1.000 12.56896 ? 101 TRP A CD1 1 
ATOM   774  C CD2 . TRP A 1 101 ? -8.81857  15.60249 -15.66030 1.000 10.87353 ? 101 TRP A CD2 1 
ATOM   775  N NE1 . TRP A 1 101 ? -9.70526  14.44219 -13.95398 1.000 11.62210 ? 101 TRP A NE1 1 
ATOM   776  C CE2 . TRP A 1 101 ? -9.88023  15.56017 -14.73199 1.000 9.70306  ? 101 TRP A CE2 1 
ATOM   777  C CE3 . TRP A 1 101 ? -8.75813  16.65830 -16.57842 1.000 10.90900 ? 101 TRP A CE3 1 
ATOM   778  C CZ2 . TRP A 1 101 ? -10.87174 16.55122 -14.68191 1.000 11.18589 ? 101 TRP A CZ2 1 
ATOM   779  C CZ3 . TRP A 1 101 ? -9.74441  17.63731 -16.54527 1.000 12.47863 ? 101 TRP A CZ3 1 
ATOM   780  C CH2 . TRP A 1 101 ? -10.79181 17.57648 -15.59686 1.000 13.19035 ? 101 TRP A CH2 1 
ATOM   781  N N   . VAL A 1 102 ? -5.34159  12.23027 -18.59713 1.000 8.30198  ? 102 VAL A N   1 
ATOM   782  C CA  . VAL A 1 102 ? -4.16066  11.91298 -19.40146 1.000 7.96930  ? 102 VAL A CA  1 
ATOM   783  C C   . VAL A 1 102 ? -4.20698  12.74379 -20.67091 1.000 9.38455  ? 102 VAL A C   1 
ATOM   784  O O   . VAL A 1 102 ? -5.10790  12.55169 -21.49433 1.000 10.80164 ? 102 VAL A O   1 
ATOM   785  C CB  . VAL A 1 102 ? -4.08250  10.42051 -19.77680 1.000 9.17146  ? 102 VAL A CB  1 
ATOM   786  C CG1 . VAL A 1 102 ? -2.83303  10.14720 -20.61767 1.000 11.71148 ? 102 VAL A CG1 1 
ATOM   787  C CG2 . VAL A 1 102 ? -4.05917  9.53054  -18.52682 1.000 11.48792 ? 102 VAL A CG2 1 
ATOM   788  N N   . TYR A 1 103 ? -3.24335  13.65529 -20.84189 1.000 8.60391  ? 103 TYR A N   1 
ATOM   789  C CA  . TYR A 1 103 ? -3.09901  14.43239 -22.07620 1.000 8.88978  ? 103 TYR A CA  1 
ATOM   790  C C   . TYR A 1 103 ? -1.75669  14.12511 -22.72995 1.000 9.12675  ? 103 TYR A C   1 
ATOM   791  O O   . TYR A 1 103 ? -0.72235  14.13481 -22.05884 1.000 9.81274  ? 103 TYR A O   1 
ATOM   792  C CB  . TYR A 1 103 ? -3.16101  15.94681 -21.81914 1.000 8.94644  ? 103 TYR A CB  1 
ATOM   793  C CG  . TYR A 1 103 ? -4.47423  16.50877 -21.34598 1.000 9.24586  ? 103 TYR A CG  1 
ATOM   794  C CD1 . TYR A 1 103 ? -5.61075  15.71409 -21.23944 1.000 10.23008 ? 103 TYR A CD1 1 
ATOM   795  C CD2 . TYR A 1 103 ? -4.58717  17.86211 -21.03410 1.000 7.80020  ? 103 TYR A CD2 1 
ATOM   796  C CE1 . TYR A 1 103 ? -6.82357  16.25389 -20.82572 1.000 11.81787 ? 103 TYR A CE1 1 
ATOM   797  C CE2 . TYR A 1 103 ? -5.77700  18.40703 -20.62780 1.000 8.69536  ? 103 TYR A CE2 1 
ATOM   798  C CZ  . TYR A 1 103 ? -6.90074  17.59846 -20.51771 1.000 11.05691 ? 103 TYR A CZ  1 
ATOM   799  O OH  . TYR A 1 103 ? -8.09610  18.14551 -20.10762 1.000 11.95405 ? 103 TYR A OH  1 
ATOM   800  N N   . PHE A 1 104 ? -1.75552  13.92249 -24.04389 1.000 9.24036  ? 104 PHE A N   1 
ATOM   801  C CA  . PHE A 1 104 ? -0.52037  13.75501 -24.80748 1.000 8.22955  ? 104 PHE A CA  1 
ATOM   802  C C   . PHE A 1 104 ? -0.25554  14.97959 -25.67142 1.000 10.38414 ? 104 PHE A C   1 
ATOM   803  O O   . PHE A 1 104 ? -1.10903  15.36389 -26.48030 1.000 9.90549  ? 104 PHE A O   1 
ATOM   804  C CB  . PHE A 1 104 ? -0.58558  12.54051 -25.73976 1.000 10.52402 ? 104 PHE A CB  1 
ATOM   805  C CG  . PHE A 1 104 ? -0.63971  11.21281 -25.03350 1.000 10.28868 ? 104 PHE A CG  1 
ATOM   806  C CD1 . PHE A 1 104 ? -0.29379  11.08195 -23.69683 1.000 11.73378 ? 104 PHE A CD1 1 
ATOM   807  C CD2 . PHE A 1 104 ? -1.02741  10.08831 -25.73374 1.000 11.88821 ? 104 PHE A CD2 1 
ATOM   808  C CE1 . PHE A 1 104 ? -0.33857  9.84434  -23.07330 1.000 11.11270 ? 104 PHE A CE1 1 
ATOM   809  C CE2 . PHE A 1 104 ? -1.07323  8.85700  -25.12277 1.000 10.68410 ? 104 PHE A CE2 1 
ATOM   810  C CZ  . PHE A 1 104 ? -0.73343  8.72944  -23.78635 1.000 12.00951 ? 104 PHE A CZ  1 
ATOM   811  N N   . GLY A 1 105 ? 0.92966   15.57012 -25.51747 1.000 10.62358 ? 105 GLY A N   1 
ATOM   812  C CA  . GLY A 1 105 ? 1.42038   16.60100 -26.41899 1.000 9.75611  ? 105 GLY A CA  1 
ATOM   813  C C   . GLY A 1 105 ? 2.53317   16.05202 -27.29565 1.000 12.57786 ? 105 GLY A C   1 
ATOM   814  O O   . GLY A 1 105 ? 3.30282   15.19074 -26.87019 1.000 12.31240 ? 105 GLY A O   1 
ATOM   815  N N   . GLU A 1 106 ? 2.61188   16.53616 -28.53219 1.000 11.56698 ? 106 GLU A N   1 
ATOM   816  C CA  . GLU A 1 106 ? 3.59107   16.03586 -29.49245 1.000 9.92544  ? 106 GLU A CA  1 
ATOM   817  C C   . GLU A 1 106 ? 4.40826   17.17744 -30.07146 1.000 11.80540 ? 106 GLU A C   1 
ATOM   818  O O   . GLU A 1 106 ? 3.89394   18.27653 -30.30541 1.000 11.52846 ? 106 GLU A O   1 
ATOM   819  C CB  . GLU A 1 106 ? 2.94051   15.28154 -30.66748 1.000 11.31636 ? 106 GLU A CB  1 
ATOM   820  C CG  . GLU A 1 106 ? 2.02751   14.16181 -30.28648 1.000 10.97954 ? 106 GLU A CG  1 
ATOM   821  C CD  . GLU A 1 106 ? 1.06453   13.86067 -31.40464 1.000 12.13246 ? 106 GLU A CD  1 
ATOM   822  O OE1 . GLU A 1 106 ? 0.04458   14.56867 -31.46922 1.000 12.54725 ? 106 GLU A OE1 1 
ATOM   823  O OE2 . GLU A 1 106 ? 1.32749   12.92206 -32.18582 1.000 13.48615 ? 106 GLU A OE2 1 
ATOM   824  N N   . MET A 1 107 ? 5.68065   16.88440 -30.33419 1.000 10.03298 ? 107 MET A N   1 
ATOM   825  C CA  . MET A 1 107 ? 6.62758   17.85013 -30.86133 1.000 10.19338 ? 107 MET A CA  1 
ATOM   826  C C   . MET A 1 107 ? 7.46735   17.17325 -31.93545 1.000 9.77335  ? 107 MET A C   1 
ATOM   827  O O   . MET A 1 107 ? 7.67619   15.95438 -31.87924 1.000 11.79086 ? 107 MET A O   1 
ATOM   828  C CB  . MET A 1 107 ? 7.56046   18.36152 -29.75762 1.000 11.77953 ? 107 MET A CB  1 
ATOM   829  C CG  . MET A 1 107 ? 6.90200   19.35343 -28.80767 1.000 10.53980 ? 107 MET A CG  1 
ATOM   830  S SD  . MET A 1 107 ? 7.64467   19.14087 -27.14543 1.000 13.89990 ? 107 MET A SD  1 
ATOM   831  C CE  . MET A 1 107 ? 6.99398   17.52890 -26.70142 1.000 16.21313 ? 107 MET A CE  1 
ATOM   832  N N   . PRO A 1 108 ? 7.99778   17.93090 -32.89338 1.000 9.95101  ? 108 PRO A N   1 
ATOM   833  C CA  . PRO A 1 108 ? 8.95637   17.33265 -33.83025 1.000 10.88682 ? 108 PRO A CA  1 
ATOM   834  C C   . PRO A 1 108 ? 10.18268  16.81082 -33.09338 1.000 11.80043 ? 108 PRO A C   1 
ATOM   835  O O   . PRO A 1 108 ? 10.71288  17.46724 -32.19469 1.000 12.02390 ? 108 PRO A O   1 
ATOM   836  C CB  . PRO A 1 108 ? 9.31667   18.49102 -34.76683 1.000 12.07882 ? 108 PRO A CB  1 
ATOM   837  C CG  . PRO A 1 108 ? 8.17404   19.44872 -34.65101 1.000 15.20848 ? 108 PRO A CG  1 
ATOM   838  C CD  . PRO A 1 108 ? 7.69745   19.33426 -33.22765 1.000 12.36435 ? 108 PRO A CD  1 
ATOM   839  N N   . ALA A 1 109 ? 10.62880  15.61433 -33.48573 1.000 13.29849 ? 109 ALA A N   1 
ATOM   840  C CA  . ALA A 1 109 ? 11.79273  15.01263 -32.83223 1.000 13.24343 ? 109 ALA A CA  1 
ATOM   841  C C   . ALA A 1 109 ? 13.00881  15.92066 -32.90535 1.000 13.93580 ? 109 ALA A C   1 
ATOM   842  O O   . ALA A 1 109 ? 13.85911  15.88943 -32.00555 1.000 13.04426 ? 109 ALA A O   1 
ATOM   843  C CB  . ALA A 1 109 ? 12.10245  13.64897 -33.45573 1.000 14.71442 ? 109 ALA A CB  1 
ATOM   844  N N   . GLN A 1 110 ? 13.08908  16.75609 -33.94368 1.000 12.92819 ? 110 GLN A N   1 
ATOM   845  C CA  A GLN A 1 110 ? 14.23450  17.63344 -34.15163 0.579 13.93829 ? 110 GLN A CA  1 
ATOM   846  C CA  B GLN A 1 110 ? 14.23207  17.63917 -34.15336 0.421 13.95915 ? 110 GLN A CA  1 
ATOM   847  C C   . GLN A 1 110 ? 14.38082  18.70257 -33.07345 1.000 13.97850 ? 110 GLN A C   1 
ATOM   848  O O   . GLN A 1 110 ? 15.42800  19.35598 -33.01801 1.000 13.80277 ? 110 GLN A O   1 
ATOM   849  C CB  A GLN A 1 110 ? 14.13959  18.28127 -35.54240 0.579 15.97781 ? 110 GLN A CB  1 
ATOM   850  C CB  B GLN A 1 110 ? 14.11934  18.31651 -35.52168 0.421 15.98175 ? 110 GLN A CB  1 
ATOM   851  C CG  A GLN A 1 110 ? 14.23272  17.29887 -36.73003 0.579 19.62065 ? 110 GLN A CG  1 
ATOM   852  C CG  B GLN A 1 110 ? 14.30523  17.37698 -36.70155 0.421 19.60321 ? 110 GLN A CG  1 
ATOM   853  C CD  A GLN A 1 110 ? 12.98896  16.43177 -36.95703 0.579 20.99881 ? 110 GLN A CD  1 
ATOM   854  C CD  B GLN A 1 110 ? 15.06560  18.02507 -37.83953 0.421 18.58818 ? 110 GLN A CD  1 
ATOM   855  O OE1 A GLN A 1 110 ? 11.86431  16.80188 -36.60247 0.579 15.32866 ? 110 GLN A OE1 1 
ATOM   856  O OE1 B GLN A 1 110 ? 14.63857  19.04281 -38.37508 0.421 19.87047 ? 110 GLN A OE1 1 
ATOM   857  N NE2 A GLN A 1 110 ? 13.19578  15.26930 -37.58237 0.579 20.45460 ? 110 GLN A NE2 1 
ATOM   858  N NE2 B GLN A 1 110 ? 16.18157  17.42593 -38.23011 0.421 24.42035 ? 110 GLN A NE2 1 
ATOM   859  N N   . GLN A 1 111 ? 13.37070  18.90514 -32.22320 1.000 12.24938 ? 111 GLN A N   1 
ATOM   860  C CA  . GLN A 1 111 ? 13.47849  19.85805 -31.11981 1.000 13.21537 ? 111 GLN A CA  1 
ATOM   861  C C   . GLN A 1 111 ? 13.26979  19.15767 -29.78203 1.000 10.94556 ? 111 GLN A C   1 
ATOM   862  O O   . GLN A 1 111 ? 12.72990  19.73925 -28.82750 1.000 10.96027 ? 111 GLN A O   1 
ATOM   863  C CB  . GLN A 1 111 ? 12.50462  21.02959 -31.28077 1.000 11.10813 ? 111 GLN A CB  1 
ATOM   864  C CG  . GLN A 1 111 ? 11.02298  20.65677 -31.29894 1.000 10.44546 ? 111 GLN A CG  1 
ATOM   865  C CD  . GLN A 1 111 ? 10.16109  21.69277 -32.02931 1.000 12.12698 ? 111 GLN A CD  1 
ATOM   866  O OE1 . GLN A 1 111 ? 10.40305  22.00999 -33.19898 1.000 11.67527 ? 111 GLN A OE1 1 
ATOM   867  N NE2 . GLN A 1 111 ? 9.15313   22.21709 -31.34180 1.000 10.13614 ? 111 GLN A NE2 1 
ATOM   868  N N   . MET A 1 112 ? 13.73930  17.90830 -29.69094 1.000 12.24675 ? 112 MET A N   1 
ATOM   869  C CA  . MET A 1 112 ? 13.54139  17.06256 -28.51960 1.000 9.81834  ? 112 MET A CA  1 
ATOM   870  C C   . MET A 1 112 ? 14.86486  16.37120 -28.21443 1.000 12.83234 ? 112 MET A C   1 
ATOM   871  O O   . MET A 1 112 ? 15.46062  15.75753 -29.10446 1.000 13.67829 ? 112 MET A O   1 
ATOM   872  C CB  . MET A 1 112 ? 12.46711  16.03079 -28.82869 1.000 11.58333 ? 112 MET A CB  1 
ATOM   873  C CG  . MET A 1 112 ? 11.07230  16.66682 -28.89543 1.000 10.12953 ? 112 MET A CG  1 
ATOM   874  S SD  . MET A 1 112 ? 9.79442   15.42994 -29.09781 1.000 12.38047 ? 112 MET A SD  1 
ATOM   875  C CE  . MET A 1 112 ? 9.90742   14.54951 -27.54369 1.000 13.54669 ? 112 MET A CE  1 
ATOM   876  N N   . VAL A 1 113 ? 15.30858  16.46040 -26.96396 1.000 9.58912  ? 113 VAL A N   1 
ATOM   877  C CA  . VAL A 1 113 ? 16.62612  15.99258 -26.53998 1.000 11.95007 ? 113 VAL A CA  1 
ATOM   878  C C   . VAL A 1 113 ? 16.42655  15.11813 -25.31126 1.000 11.28556 ? 113 VAL A C   1 
ATOM   879  O O   . VAL A 1 113 ? 15.85034  15.57450 -24.31685 1.000 11.49663 ? 113 VAL A O   1 
ATOM   880  C CB  . VAL A 1 113 ? 17.57028  17.17028 -26.22105 1.000 11.24609 ? 113 VAL A CB  1 
ATOM   881  C CG1 . VAL A 1 113 ? 18.82164  16.67813 -25.51278 1.000 10.81149 ? 113 VAL A CG1 1 
ATOM   882  C CG2 . VAL A 1 113 ? 17.94872  17.95331 -27.48149 1.000 11.29835 ? 113 VAL A CG2 1 
ATOM   883  N N   . ASP A 1 114 ? 16.86187  13.85776 -25.39130 1.000 10.01949 ? 114 ASP A N   1 
ATOM   884  C CA  . ASP A 1 114 ? 16.94783  12.96896 -24.23511 1.000 12.63068 ? 114 ASP A CA  1 
ATOM   885  C C   . ASP A 1 114 ? 18.42100  12.69493 -23.96911 1.000 11.93943 ? 114 ASP A C   1 
ATOM   886  O O   . ASP A 1 114 ? 19.18330  12.45431 -24.90091 1.000 14.17950 ? 114 ASP A O   1 
ATOM   887  C CB  . ASP A 1 114 ? 16.26510  11.61082 -24.45645 1.000 14.02496 ? 114 ASP A CB  1 
ATOM   888  C CG  . ASP A 1 114 ? 14.76215  11.69728 -24.64553 1.000 14.30844 ? 114 ASP A CG  1 
ATOM   889  O OD1 . ASP A 1 114 ? 14.18451  12.79882 -24.60136 1.000 12.35397 ? 114 ASP A OD1 1 
ATOM   890  O OD2 . ASP A 1 114 ? 14.14262  10.62286 -24.81391 1.000 14.00396 ? 114 ASP A OD2 1 
ATOM   891  N N   . TYR A 1 115 ? 18.82990  12.71989 -22.70481 1.000 12.74808 ? 115 TYR A N   1 
ATOM   892  C CA  . TYR A 1 115 ? 20.21360  12.36816 -22.37664 1.000 14.42549 ? 115 TYR A CA  1 
ATOM   893  C C   . TYR A 1 115 ? 21.21796  13.22942 -23.14778 1.000 13.41189 ? 115 TYR A C   1 
ATOM   894  O O   . TYR A 1 115 ? 22.29257  12.75950 -23.53734 1.000 14.86275 ? 115 TYR A O   1 
ATOM   895  C CB  . TYR A 1 115 ? 20.47742  10.88019 -22.65880 1.000 15.32990 ? 115 TYR A CB  1 
ATOM   896  C CG  . TYR A 1 115 ? 19.74331  9.87439  -21.79934 1.000 13.59956 ? 115 TYR A CG  1 
ATOM   897  C CD1 . TYR A 1 115 ? 20.24336  9.49088  -20.56259 1.000 17.31488 ? 115 TYR A CD1 1 
ATOM   898  C CD2 . TYR A 1 115 ? 18.57227  9.26927  -22.24235 1.000 15.18976 ? 115 TYR A CD2 1 
ATOM   899  C CE1 . TYR A 1 115 ? 19.57981  8.53781  -19.78098 1.000 20.07289 ? 115 TYR A CE1 1 
ATOM   900  C CE2 . TYR A 1 115 ? 17.90507  8.32350  -21.46551 1.000 13.14946 ? 115 TYR A CE2 1 
ATOM   901  C CZ  . TYR A 1 115 ? 18.41521  7.96742  -20.23651 1.000 16.06639 ? 115 TYR A CZ  1 
ATOM   902  O OH  . TYR A 1 115 ? 17.76735  7.02375  -19.47283 1.000 18.77534 ? 115 TYR A OH  1 
ATOM   903  N N   . GLY A 1 116 ? 20.88203  14.49319 -23.41982 1.000 12.99196 ? 116 GLY A N   1 
ATOM   904  C CA  . GLY A 1 116 ? 21.79051  15.37472 -24.12186 1.000 13.04326 ? 116 GLY A CA  1 
ATOM   905  C C   . GLY A 1 116 ? 21.90722  15.14106 -25.61544 1.000 14.93389 ? 116 GLY A C   1 
ATOM   906  O O   . GLY A 1 116 ? 22.71292  15.82145 -26.27047 1.000 16.24663 ? 116 GLY A O   1 
ATOM   907  N N   . ARG A 1 117 ? 21.12235  14.23145 -26.17461 1.000 12.85391 ? 117 ARG A N   1 
ATOM   908  C CA  . ARG A 1 117 ? 21.16012  13.92190 -27.59716 1.000 15.22804 ? 117 ARG A CA  1 
ATOM   909  C C   . ARG A 1 117 ? 19.78109  14.08840 -28.22538 1.000 13.10774 ? 117 ARG A C   1 
ATOM   910  O O   . ARG A 1 117 ? 18.75892  13.79155 -27.60103 1.000 15.10026 ? 117 ARG A O   1 
ATOM   911  C CB  . ARG A 1 117 ? 21.69781  12.50547 -27.84286 1.000 21.15290 ? 117 ARG A CB  1 
ATOM   912  C CG  . ARG A 1 117 ? 22.98553  12.22491 -27.06424 1.000 19.58674 ? 117 ARG A CG  1 
ATOM   913  C CD  . ARG A 1 117 ? 24.18958  12.87622 -27.76324 1.000 26.96083 ? 117 ARG A CD  1 
ATOM   914  N NE  . ARG A 1 117 ? 24.21332  12.71360 -29.21321 1.000 31.98563 ? 117 ARG A NE  1 
ATOM   915  C CZ  . ARG A 1 117 ? 24.94139  11.81770 -29.86872 1.000 38.75253 ? 117 ARG A CZ  1 
ATOM   916  N NH1 . ARG A 1 117 ? 25.80547  11.03282 -29.24282 1.000 36.79208 ? 117 ARG A NH1 1 
ATOM   917  N NH2 . ARG A 1 117 ? 24.82846  11.73336 -31.19134 1.000 37.07566 ? 117 ARG A NH2 1 
ATOM   918  N N   . PHE A 1 118 ? 19.75941  14.58902 -29.45785 1.000 12.78871 ? 118 PHE A N   1 
ATOM   919  C CA  . PHE A 1 118 ? 18.50463  14.75386 -30.17336 1.000 12.85872 ? 118 PHE A CA  1 
ATOM   920  C C   . PHE A 1 118 ? 17.91841  13.39649 -30.52474 1.000 15.41181 ? 118 PHE A C   1 
ATOM   921  O O   . PHE A 1 118 ? 18.63985  12.46909 -30.90294 1.000 16.81818 ? 118 PHE A O   1 
ATOM   922  C CB  . PHE A 1 118 ? 18.73023  15.56964 -31.44106 1.000 13.93792 ? 118 PHE A CB  1 
ATOM   923  C CG  . PHE A 1 118 ? 18.93073  17.02386 -31.18923 1.000 15.13347 ? 118 PHE A CG  1 
ATOM   924  C CD1 . PHE A 1 118 ? 20.20020  17.53687 -30.97218 1.000 16.47270 ? 118 PHE A CD1 1 
ATOM   925  C CD2 . PHE A 1 118 ? 17.84443  17.88824 -31.14566 1.000 14.88560 ? 118 PHE A CD2 1 
ATOM   926  C CE1 . PHE A 1 118 ? 20.39067  18.88519 -30.73490 1.000 21.79569 ? 118 PHE A CE1 1 
ATOM   927  C CE2 . PHE A 1 118 ? 18.03234  19.23598 -30.91086 1.000 14.13810 ? 118 PHE A CE2 1 
ATOM   928  C CZ  . PHE A 1 118 ? 19.29192  19.74050 -30.70273 1.000 17.24969 ? 118 PHE A CZ  1 
ATOM   929  N N   . LEU A 1 119 ? 16.60216  13.29040 -30.40867 1.000 14.33239 ? 119 LEU A N   1 
ATOM   930  C CA  . LEU A 1 119 ? 15.89023  12.05319 -30.64984 1.000 16.54281 ? 119 LEU A CA  1 
ATOM   931  C C   . LEU A 1 119 ? 15.79931  11.74884 -32.13978 1.000 19.48229 ? 119 LEU A C   1 
ATOM   932  O O   . LEU A 1 119 ? 15.83966  12.65742 -32.97625 1.000 18.88987 ? 119 LEU A O   1 
ATOM   933  C CB  . LEU A 1 119 ? 14.48085  12.13311 -30.07069 1.000 15.97499 ? 119 LEU A CB  1 
ATOM   934  C CG  . LEU A 1 119 ? 14.40838  12.11599 -28.55015 1.000 13.79099 ? 119 LEU A CG  1 
ATOM   935  C CD1 . LEU A 1 119 ? 12.94592  12.19179 -28.07436 1.000 18.52044 ? 119 LEU A CD1 1 
ATOM   936  C CD2 . LEU A 1 119 ? 15.08306  10.87790 -28.02285 1.000 21.52889 ? 119 LEU A CD2 1 
ATOM   937  N N   . PRO A 1 120 ? 15.63724  10.46886 -32.48796 1.000 19.55304 ? 120 PRO A N   1 
ATOM   938  C CA  . PRO A 1 120 ? 15.30721  10.10806 -33.87017 1.000 19.70098 ? 120 PRO A CA  1 
ATOM   939  C C   . PRO A 1 120 ? 13.80687  10.13554 -34.12278 1.000 24.64227 ? 120 PRO A C   1 
ATOM   940  O O   . PRO A 1 120 ? 13.01383  10.38370 -33.21011 1.000 24.45339 ? 120 PRO A O   1 
ATOM   941  C CB  . PRO A 1 120 ? 15.84090  8.67960  -33.97082 1.000 21.00230 ? 120 PRO A CB  1 
ATOM   942  C CG  . PRO A 1 120 ? 15.52109  8.10901  -32.58180 1.000 24.15760 ? 120 PRO A CG  1 
ATOM   943  C CD  . PRO A 1 120 ? 15.52547  9.29647  -31.59942 1.000 19.87184 ? 120 PRO A CD  1 
ATOM   944  N N   . GLN A 1 121 ? 13.40222  9.84422  -35.35410 1.000 34.68610 ? 121 GLN A N   1 
ATOM   945  C CA  . GLN A 1 121 ? 12.00045  9.56838  -35.62604 1.000 31.00422 ? 121 GLN A CA  1 
ATOM   946  C C   . GLN A 1 121 ? 11.59048  8.26042  -34.94904 1.000 33.75533 ? 121 GLN A C   1 
ATOM   947  O O   . GLN A 1 121 ? 12.41666  7.35565  -34.81668 1.000 38.48368 ? 121 GLN A O   1 
ATOM   948  C CB  . GLN A 1 121 ? 11.77177  9.48940  -37.13192 1.000 31.99261 ? 121 GLN A CB  1 
ATOM   949  C CG  . GLN A 1 121 ? 10.36107  9.77959  -37.57287 1.000 41.94062 ? 121 GLN A CG  1 
ATOM   950  C CD  . GLN A 1 121 ? 9.98070   11.25153 -37.48852 1.000 42.09922 ? 121 GLN A CD  1 
ATOM   951  O OE1 . GLN A 1 121 ? 10.51739  12.01075 -36.67484 1.000 34.66447 ? 121 GLN A OE1 1 
ATOM   952  N NE2 . GLN A 1 121 ? 9.03399   11.65855 -38.33012 1.000 41.74153 ? 121 GLN A NE2 1 
ATOM   953  N N   . PRO A 1 122 ? 10.29796  8.13876  -34.48881 1.000 33.71115 ? 122 PRO A N   1 
ATOM   954  C CA  . PRO A 1 122 ? 9.88944   6.95597  -33.70358 1.000 34.61340 ? 122 PRO A CA  1 
ATOM   955  C C   . PRO A 1 122 ? 10.55394  5.63498  -34.06854 1.000 38.68027 ? 122 PRO A C   1 
ATOM   956  O O   . PRO A 1 122 ? 11.56568  5.29658  -33.45612 1.000 41.71404 ? 122 PRO A O   1 
ATOM   957  C CB  . PRO A 1 122 ? 8.37200   6.90976  -33.91491 1.000 34.29767 ? 122 PRO A CB  1 
ATOM   958  C CG  . PRO A 1 122 ? 7.98924   8.37019  -34.04089 1.000 32.55795 ? 122 PRO A CG  1 
ATOM   959  C CD  . PRO A 1 122 ? 9.19649   9.11887  -34.59381 1.000 29.64100 ? 122 PRO A CD  1 
ATOM   960  N N   . GLY A 1 123 ? 10.05702  4.89517  -35.05302 1.000 42.84315 ? 123 GLY A N   1 
ATOM   961  C CA  . GLY A 1 123 ? 10.54558  3.53963  -35.27196 1.000 36.63805 ? 123 GLY A CA  1 
ATOM   962  C C   . GLY A 1 123 ? 12.04229  3.29744  -35.42178 1.000 38.94635 ? 123 GLY A C   1 
ATOM   963  O O   . GLY A 1 123 ? 12.45303  2.14413  -35.59890 1.000 41.21429 ? 123 GLY A O   1 
ATOM   964  N N   . HIS A 1 124 ? 12.86747  4.34789  -35.33025 1.000 37.16377 ? 124 HIS A N   1 
ATOM   965  C CA  . HIS A 1 124 ? 14.29372  4.29540  -35.65992 1.000 38.86613 ? 124 HIS A CA  1 
ATOM   966  C C   . HIS A 1 124 ? 15.17912  4.43173  -34.42698 1.000 32.53277 ? 124 HIS A C   1 
ATOM   967  O O   . HIS A 1 124 ? 16.24466  5.04424  -34.46060 1.000 35.96557 ? 124 HIS A O   1 
ATOM   968  C CB  . HIS A 1 124 ? 14.64327  5.36677  -36.68446 1.000 38.72968 ? 124 HIS A CB  1 
ATOM   969  C CG  . HIS A 1 124 ? 13.81668  5.28467  -37.92512 1.000 37.19864 ? 124 HIS A CG  1 
ATOM   970  N ND1 . HIS A 1 124 ? 13.53753  4.08761  -38.54827 1.000 40.97512 ? 124 HIS A ND1 1 
ATOM   971  C CD2 . HIS A 1 124 ? 13.19446  6.24217  -38.65082 1.000 41.53548 ? 124 HIS A CD2 1 
ATOM   972  C CE1 . HIS A 1 124 ? 12.78369  4.31173  -39.60984 1.000 41.03044 ? 124 HIS A CE1 1 
ATOM   973  N NE2 . HIS A 1 124 ? 12.56183  5.61080  -39.69516 1.000 46.86886 ? 124 HIS A NE2 1 
ATOM   974  N N   . GLU A 1 125 ? 14.74734  3.81123  -33.34021 1.000 31.57154 ? 125 GLU A N   1 
ATOM   975  C CA  . GLU A 1 125 ? 15.38137  3.91071  -32.03843 1.000 35.43769 ? 125 GLU A CA  1 
ATOM   976  C C   . GLU A 1 125 ? 16.55025  2.95155  -31.87413 1.000 39.39964 ? 125 GLU A C   1 
ATOM   977  O O   . GLU A 1 125 ? 17.42019  3.19681  -31.03221 1.000 34.21743 ? 125 GLU A O   1 
ATOM   978  C CB  . GLU A 1 125 ? 14.28601  3.65307  -31.02479 1.000 36.93145 ? 125 GLU A CB  1 
ATOM   979  C CG  . GLU A 1 125 ? 13.27914  4.75600  -31.13807 1.000 40.49879 ? 125 GLU A CG  1 
ATOM   980  C CD  . GLU A 1 125 ? 11.94041  4.37830  -30.60067 1.000 44.32307 ? 125 GLU A CD  1 
ATOM   981  O OE1 . GLU A 1 125 ? 11.73334  3.16436  -30.40347 1.000 47.45166 ? 125 GLU A OE1 1 
ATOM   982  O OE2 . GLU A 1 125 ? 11.07819  5.27307  -30.45380 1.000 43.71971 ? 125 GLU A OE2 1 
ATOM   983  N N   . GLY A 1 126 ? 16.58929  1.87341  -32.65956 1.000 39.15724 ? 126 GLY A N   1 
ATOM   984  C CA  . GLY A 1 126 ? 17.71930  0.96328  -32.58895 1.000 35.24092 ? 126 GLY A CA  1 
ATOM   985  C C   . GLY A 1 126 ? 18.97386  1.54310  -33.21738 1.000 38.74898 ? 126 GLY A C   1 
ATOM   986  O O   . GLY A 1 126 ? 20.03934  1.56818  -32.59418 1.000 41.60699 ? 126 GLY A O   1 
ATOM   987  N N   . GLU A 1 127 ? 18.86583  2.01885  -34.46105 1.000 31.02388 ? 127 GLU A N   1 
ATOM   988  C CA  . GLU A 1 127 ? 20.03974  2.53848  -35.15706 1.000 38.40210 ? 127 GLU A CA  1 
ATOM   989  C C   . GLU A 1 127 ? 20.51523  3.85078  -34.54420 1.000 40.29023 ? 127 GLU A C   1 
ATOM   990  O O   . GLU A 1 127 ? 21.72271  4.12327  -34.50612 1.000 38.72312 ? 127 GLU A O   1 
ATOM   991  C CB  . GLU A 1 127 ? 19.73738  2.70870  -36.64847 1.000 41.22235 ? 127 GLU A CB  1 
ATOM   992  C CG  . GLU A 1 127 ? 18.71795  3.79136  -36.97685 1.000 45.20549 ? 127 GLU A CG  1 
ATOM   993  C CD  . GLU A 1 127 ? 17.51168  3.25725  -37.72856 1.000 51.71431 ? 127 GLU A CD  1 
ATOM   994  O OE1 . GLU A 1 127 ? 16.89038  2.28108  -37.24885 1.000 50.19033 ? 127 GLU A OE1 1 
ATOM   995  O OE2 . GLU A 1 127 ? 17.18071  3.81944  -38.79745 1.000 54.68708 ? 127 GLU A OE2 1 
ATOM   996  N N   . TRP A 1 128 ? 19.57917  4.68602  -34.08292 1.000 38.80385 ? 128 TRP A N   1 
ATOM   997  C CA  . TRP A 1 128 ? 19.93768  5.85014  -33.27866 1.000 36.10002 ? 128 TRP A CA  1 
ATOM   998  C C   . TRP A 1 128 ? 20.78253  5.44381  -32.08178 1.000 32.61407 ? 128 TRP A C   1 
ATOM   999  O O   . TRP A 1 128 ? 21.83151  6.04253  -31.80535 1.000 30.46577 ? 128 TRP A O   1 
ATOM   1000 C CB  . TRP A 1 128 ? 18.66429  6.55784  -32.82047 1.000 29.07640 ? 128 TRP A CB  1 
ATOM   1001 C CG  . TRP A 1 128 ? 18.87369  7.69214  -31.85324 1.000 23.00067 ? 128 TRP A CG  1 
ATOM   1002 C CD1 . TRP A 1 128 ? 19.19847  8.98882  -32.14855 1.000 23.74864 ? 128 TRP A CD1 1 
ATOM   1003 C CD2 . TRP A 1 128 ? 18.73888  7.62644  -30.42668 1.000 25.27180 ? 128 TRP A CD2 1 
ATOM   1004 N NE1 . TRP A 1 128 ? 19.28808  9.72683  -30.98501 1.000 24.38620 ? 128 TRP A NE1 1 
ATOM   1005 C CE2 . TRP A 1 128 ? 19.00578  8.91139  -29.92005 1.000 23.06387 ? 128 TRP A CE2 1 
ATOM   1006 C CE3 . TRP A 1 128 ? 18.43014  6.59898  -29.52953 1.000 26.29984 ? 128 TRP A CE3 1 
ATOM   1007 C CZ2 . TRP A 1 128 ? 18.96877  9.19450  -28.55701 1.000 22.33504 ? 128 TRP A CZ2 1 
ATOM   1008 C CZ3 . TRP A 1 128 ? 18.39266  6.88285  -28.17897 1.000 26.87039 ? 128 TRP A CZ3 1 
ATOM   1009 C CH2 . TRP A 1 128 ? 18.65981  8.16843  -27.70664 1.000 22.65805 ? 128 TRP A CH2 1 
ATOM   1010 N N   . PHE A 1 129 ? 20.33606  4.40955  -31.36763 1.000 34.07515 ? 129 PHE A N   1 
ATOM   1011 C CA  . PHE A 1 129 ? 21.03582  3.96273  -30.17036 1.000 36.13225 ? 129 PHE A CA  1 
ATOM   1012 C C   . PHE A 1 129 ? 22.40691  3.39309  -30.50220 1.000 38.50786 ? 129 PHE A C   1 
ATOM   1013 O O   . PHE A 1 129 ? 23.34345  3.54316  -29.71195 1.000 31.91235 ? 129 PHE A O   1 
ATOM   1014 C CB  . PHE A 1 129 ? 20.19160  2.92057  -29.44028 1.000 34.30860 ? 129 PHE A CB  1 
ATOM   1015 C CG  . PHE A 1 129 ? 20.81746  2.40294  -28.17712 1.000 39.24466 ? 129 PHE A CG  1 
ATOM   1016 C CD1 . PHE A 1 129 ? 21.18523  1.07051  -28.06640 1.000 37.08140 ? 129 PHE A CD1 1 
ATOM   1017 C CD2 . PHE A 1 129 ? 21.01572  3.24182  -27.09034 1.000 35.29938 ? 129 PHE A CD2 1 
ATOM   1018 C CE1 . PHE A 1 129 ? 21.75749  0.58735  -26.90189 1.000 35.46442 ? 129 PHE A CE1 1 
ATOM   1019 C CE2 . PHE A 1 129 ? 21.58689  2.76587  -25.92055 1.000 35.84946 ? 129 PHE A CE2 1 
ATOM   1020 C CZ  . PHE A 1 129 ? 21.96048  1.43664  -25.82649 1.000 37.52998 ? 129 PHE A CZ  1 
ATOM   1021 N N   . ASP A 1 130 ? 22.54425  2.74693  -31.66255 1.000 40.49623 ? 130 ASP A N   1 
ATOM   1022 C CA  . ASP A 1 130 ? 23.80418  2.10742  -32.02173 1.000 36.48738 ? 130 ASP A CA  1 
ATOM   1023 C C   . ASP A 1 130 ? 24.83284  3.11179  -32.52258 1.000 37.88861 ? 130 ASP A C   1 
ATOM   1024 O O   . ASP A 1 130 ? 26.03747  2.90001  -32.34137 1.000 43.29012 ? 130 ASP A O   1 
ATOM   1025 C CB  . ASP A 1 130 ? 23.55373  1.01676  -33.06762 1.000 40.71023 ? 130 ASP A CB  1 
ATOM   1026 C CG  . ASP A 1 130 ? 22.63265  -0.08239 -32.55510 1.000 42.80321 ? 130 ASP A CG  1 
ATOM   1027 O OD1 . ASP A 1 130 ? 22.40224  -0.14479 -31.32784 1.000 46.25596 ? 130 ASP A OD1 1 
ATOM   1028 O OD2 . ASP A 1 130 ? 22.13615  -0.88546 -33.37406 1.000 45.78538 ? 130 ASP A OD2 1 
ATOM   1029 N N   . ASN A 1 131 ? 24.39482  4.20736  -33.13906 1.000 34.19533 ? 131 ASN A N   1 
ATOM   1030 C CA  . ASN A 1 131 ? 25.35271  5.24760  -33.49229 1.000 37.40733 ? 131 ASN A CA  1 
ATOM   1031 C C   . ASN A 1 131 ? 25.78811  6.06843  -32.28916 1.000 31.56004 ? 131 ASN A C   1 
ATOM   1032 O O   . ASN A 1 131 ? 26.66131  6.93097  -32.42651 1.000 36.23875 ? 131 ASN A O   1 
ATOM   1033 C CB  . ASN A 1 131 ? 24.77174  6.15765  -34.57310 1.000 43.16393 ? 131 ASN A CB  1 
ATOM   1034 C CG  . ASN A 1 131 ? 25.67942  6.26779  -35.78485 1.000 50.60947 ? 131 ASN A CG  1 
ATOM   1035 O OD1 . ASN A 1 131 ? 26.90493  6.30918  -35.65317 1.000 54.13802 ? 131 ASN A OD1 1 
ATOM   1036 N ND2 . ASN A 1 131 ? 25.08379  6.29890  -36.97447 1.000 50.88037 ? 131 ASN A ND2 1 
ATOM   1037 N N   . LEU A 1 132 ? 25.20702  5.81199  -31.12346 1.000 33.94678 ? 132 LEU A N   1 
ATOM   1038 C CA  . LEU A 1 132 ? 25.58366  6.47014  -29.88672 1.000 32.46676 ? 132 LEU A CA  1 
ATOM   1039 C C   . LEU A 1 132 ? 26.91659  5.91975  -29.38906 1.000 34.49989 ? 132 LEU A C   1 
ATOM   1040 O O   . LEU A 1 132 ? 27.29404  4.78394  -29.68172 1.000 32.15938 ? 132 LEU A O   1 
ATOM   1041 C CB  . LEU A 1 132 ? 24.49760  6.24266  -28.84245 1.000 34.50551 ? 132 LEU A CB  1 
ATOM   1042 C CG  . LEU A 1 132 ? 23.28390  7.15937  -28.96759 1.000 29.23880 ? 132 LEU A CG  1 
ATOM   1043 C CD1 . LEU A 1 132 ? 22.38011  6.94608  -27.78803 1.000 29.29462 ? 132 LEU A CD1 1 
ATOM   1044 C CD2 . LEU A 1 132 ? 23.70426  8.61492  -29.06830 1.000 35.39556 ? 132 LEU A CD2 1 
ATOM   1045 N N   . SER A 1 133 ? 27.62602  6.72931  -28.61108 1.000 29.61125 ? 133 SER A N   1 
ATOM   1046 C CA  . SER A 1 133 ? 28.91571  6.28074  -28.11399 1.000 31.84895 ? 133 SER A CA  1 
ATOM   1047 C C   . SER A 1 133 ? 28.75018  5.17090  -27.07464 1.000 29.23403 ? 133 SER A C   1 
ATOM   1048 O O   . SER A 1 133 ? 27.67661  4.95441  -26.50769 1.000 26.52267 ? 133 SER A O   1 
ATOM   1049 C CB  . SER A 1 133 ? 29.69250  7.44119  -27.50514 1.000 29.51203 ? 133 SER A CB  1 
ATOM   1050 O OG  . SER A 1 133 ? 29.29505  7.64318  -26.16564 1.000 30.04929 ? 133 SER A OG  1 
ATOM   1051 N N   . SER A 1 134 ? 29.85296  4.45925  -26.83613 1.000 31.24923 ? 134 SER A N   1 
ATOM   1052 C CA  . SER A 1 134 ? 29.87625  3.38073  -25.85012 1.000 29.23569 ? 134 SER A CA  1 
ATOM   1053 C C   . SER A 1 134 ? 29.47102  3.86497  -24.46058 1.000 22.81027 ? 134 SER A C   1 
ATOM   1054 O O   . SER A 1 134 ? 28.66990  3.21941  -23.77050 1.000 23.26533 ? 134 SER A O   1 
ATOM   1055 C CB  . SER A 1 134 ? 31.28003  2.77484  -25.81636 1.000 26.47926 ? 134 SER A CB  1 
ATOM   1056 O OG  . SER A 1 134 ? 32.11211  3.49794  -24.92220 1.000 32.91353 ? 134 SER A OG  1 
ATOM   1057 N N   . ASP A 1 135 ? 30.04824  4.98282  -24.01702 1.000 22.83082 ? 135 ASP A N   1 
ATOM   1058 C CA  . ASP A 1 135 ? 29.73403  5.51383  -22.69410 1.000 27.45734 ? 135 ASP A CA  1 
ATOM   1059 C C   . ASP A 1 135 ? 28.28382  5.96715  -22.60491 1.000 24.55664 ? 135 ASP A C   1 
ATOM   1060 O O   . ASP A 1 135 ? 27.63777  5.81202  -21.55987 1.000 20.11321 ? 135 ASP A O   1 
ATOM   1061 C CB  . ASP A 1 135 ? 30.68391  6.66013  -22.36703 1.000 24.97468 ? 135 ASP A CB  1 
ATOM   1062 C CG  . ASP A 1 135 ? 32.11521  6.19340  -22.24175 1.000 29.76095 ? 135 ASP A CG  1 
ATOM   1063 O OD1 . ASP A 1 135 ? 32.30001  5.01205  -21.88929 1.000 18.82102 ? 135 ASP A OD1 1 
ATOM   1064 O OD2 . ASP A 1 135 ? 33.04432  6.97465  -22.53833 1.000 31.85195 ? 135 ASP A OD2 1 
ATOM   1065 N N   . GLU A 1 136 ? 27.75749  6.53379  -23.68742 1.000 24.91631 ? 136 GLU A N   1 
ATOM   1066 C CA  . GLU A 1 136 ? 26.37064  6.97981  -23.66321 1.000 22.92650 ? 136 GLU A CA  1 
ATOM   1067 C C   . GLU A 1 136 ? 25.42240  5.79373  -23.60574 1.000 20.85799 ? 136 GLU A C   1 
ATOM   1068 O O   . GLU A 1 136 ? 24.44462  5.80345  -22.84901 1.000 21.09076 ? 136 GLU A O   1 
ATOM   1069 C CB  . GLU A 1 136 ? 26.09451  7.84720  -24.88504 1.000 22.57796 ? 136 GLU A CB  1 
ATOM   1070 C CG  . GLU A 1 136 ? 26.75622  9.19692  -24.77577 1.000 26.63281 ? 136 GLU A CG  1 
ATOM   1071 C CD  . GLU A 1 136 ? 26.54259  10.04648 -25.99928 1.000 31.35189 ? 136 GLU A CD  1 
ATOM   1072 O OE1 . GLU A 1 136 ? 26.97668  9.62308  -27.09075 1.000 34.52445 ? 136 GLU A OE1 1 
ATOM   1073 O OE2 . GLU A 1 136 ? 25.98906  11.15672 -25.85998 1.000 31.01734 ? 136 GLU A OE2 1 
ATOM   1074 N N   . ARG A 1 137 ? 25.70456  4.75671  -24.39567 1.000 21.50272 ? 137 ARG A N   1 
ATOM   1075 C CA  . ARG A 1 137 ? 24.93114  3.52447  -24.33733 1.000 22.14336 ? 137 ARG A CA  1 
ATOM   1076 C C   . ARG A 1 137 ? 24.94132  2.95304  -22.92985 1.000 22.69399 ? 137 ARG A C   1 
ATOM   1077 O O   . ARG A 1 137 ? 23.89330  2.60286  -22.38535 1.000 23.15514 ? 137 ARG A O   1 
ATOM   1078 C CB  . ARG A 1 137 ? 25.53065  2.51233  -25.30584 1.000 27.84672 ? 137 ARG A CB  1 
ATOM   1079 C CG  . ARG A 1 137 ? 25.25410  2.75888  -26.76780 1.000 29.79684 ? 137 ARG A CG  1 
ATOM   1080 C CD  . ARG A 1 137 ? 25.27375  1.43950  -27.51327 1.000 37.64428 ? 137 ARG A CD  1 
ATOM   1081 N NE  . ARG A 1 137 ? 26.66731  1.04970  -27.70449 1.000 32.47763 ? 137 ARG A NE  1 
ATOM   1082 C CZ  . ARG A 1 137 ? 27.48616  1.53808  -28.62583 1.000 36.10954 ? 137 ARG A CZ  1 
ATOM   1083 N NH1 . ARG A 1 137 ? 27.07596  2.42088  -29.52286 1.000 39.78084 ? 137 ARG A NH1 1 
ATOM   1084 N NH2 . ARG A 1 137 ? 28.75616  1.14204  -28.63595 1.000 42.65010 ? 137 ARG A NH2 1 
ATOM   1085 N N   . ALA A 1 138 ? 26.13181  2.86322  -22.32166 1.000 24.34930 ? 138 ALA A N   1 
ATOM   1086 C CA  . ALA A 1 138 ? 26.26383  2.23656  -21.00801 1.000 25.37373 ? 138 ALA A CA  1 
ATOM   1087 C C   . ALA A 1 138 ? 25.43928  2.96711  -19.95935 1.000 21.91509 ? 138 ALA A C   1 
ATOM   1088 O O   . ALA A 1 138 ? 24.78626  2.33373  -19.12130 1.000 23.42410 ? 138 ALA A O   1 
ATOM   1089 C CB  . ALA A 1 138 ? 27.73678  2.18984  -20.59059 1.000 25.39953 ? 138 ALA A CB  1 
ATOM   1090 N N   . PHE A 1 139 ? 25.45508  4.30313  -19.99247 1.000 22.28433 ? 139 PHE A N   1 
ATOM   1091 C CA  . PHE A 1 139 ? 24.69623  5.07399  -19.01556 1.000 21.42599 ? 139 PHE A CA  1 
ATOM   1092 C C   . PHE A 1 139 ? 23.19666  4.84719  -19.18401 1.000 19.24186 ? 139 PHE A C   1 
ATOM   1093 O O   . PHE A 1 139 ? 22.46904  4.68841  -18.19750 1.000 20.68889 ? 139 PHE A O   1 
ATOM   1094 C CB  . PHE A 1 139 ? 25.05077  6.55818  -19.14253 1.000 21.43053 ? 139 PHE A CB  1 
ATOM   1095 C CG  . PHE A 1 139 ? 24.27707  7.44853  -18.21141 1.000 22.63608 ? 139 PHE A CG  1 
ATOM   1096 C CD1 . PHE A 1 139 ? 24.61147  7.51318  -16.87127 1.000 26.61682 ? 139 PHE A CD1 1 
ATOM   1097 C CD2 . PHE A 1 139 ? 23.24381  8.24589  -18.67847 1.000 19.58179 ? 139 PHE A CD2 1 
ATOM   1098 C CE1 . PHE A 1 139 ? 23.91227  8.32882  -16.00484 1.000 28.43881 ? 139 PHE A CE1 1 
ATOM   1099 C CE2 . PHE A 1 139 ? 22.55066  9.07340  -17.82479 1.000 22.33811 ? 139 PHE A CE2 1 
ATOM   1100 C CZ  . PHE A 1 139 ? 22.87992  9.11821  -16.48539 1.000 25.11366 ? 139 PHE A CZ  1 
ATOM   1101 N N   . MET A 1 140 ? 22.72176  4.82112  -20.42867 1.000 17.25994 ? 140 MET A N   1 
ATOM   1102 C CA  . MET A 1 140 ? 21.31721  4.51955  -20.69597 1.000 18.71578 ? 140 MET A CA  1 
ATOM   1103 C C   . MET A 1 140 ? 20.92523  3.12415  -20.22215 1.000 23.42334 ? 140 MET A C   1 
ATOM   1104 O O   . MET A 1 140 ? 19.84522  2.95246  -19.65083 1.000 20.56055 ? 140 MET A O   1 
ATOM   1105 C CB  . MET A 1 140 ? 21.03028  4.67478  -22.18411 1.000 22.39080 ? 140 MET A CB  1 
ATOM   1106 C CG  . MET A 1 140 ? 21.18387  6.07949  -22.66135 1.000 22.14700 ? 140 MET A CG  1 
ATOM   1107 S SD  . MET A 1 140 ? 20.79450  6.30171  -24.40253 1.000 29.70750 ? 140 MET A SD  1 
ATOM   1108 C CE  . MET A 1 140 ? 21.60268  7.87606  -24.61631 1.000 28.00465 ? 140 MET A CE  1 
ATOM   1109 N N   . GLU A 1 141 ? 21.78089  2.11356  -20.46981 1.000 23.51396 ? 141 GLU A N   1 
ATOM   1110 C CA  . GLU A 1 141 ? 21.51141  0.73307  -20.04082 1.000 27.36005 ? 141 GLU A CA  1 
ATOM   1111 C C   . GLU A 1 141 ? 21.22668  0.62234  -18.55150 1.000 26.92269 ? 141 GLU A C   1 
ATOM   1112 O O   . GLU A 1 141 ? 20.39658  -0.19163 -18.13539 1.000 33.21798 ? 141 GLU A O   1 
ATOM   1113 C CB  . GLU A 1 141 ? 22.69632  -0.19197 -20.34046 1.000 30.78141 ? 141 GLU A CB  1 
ATOM   1114 C CG  . GLU A 1 141 ? 23.39860  -0.03193 -21.63433 1.000 35.40181 ? 141 GLU A CG  1 
ATOM   1115 C CD  . GLU A 1 141 ? 24.16198  -1.26918 -22.04034 1.000 34.36847 ? 141 GLU A CD  1 
ATOM   1116 O OE1 . GLU A 1 141 ? 24.92673  -1.79750 -21.19014 1.000 35.86175 ? 141 GLU A OE1 1 
ATOM   1117 O OE2 . GLU A 1 141 ? 24.01077  -1.69946 -23.19962 1.000 37.66550 ? 141 GLU A OE2 1 
ATOM   1118 N N   . THR A 1 142 ? 21.95581  1.37511  -17.72330 1.000 27.26954 ? 142 THR A N   1 
ATOM   1119 C CA  . THR A 1 142 ? 21.71077  1.28569  -16.29112 1.000 25.84097 ? 142 THR A CA  1 
ATOM   1120 C C   . THR A 1 142 ? 20.28478  1.66555  -15.92919 1.000 27.18265 ? 142 THR A C   1 
ATOM   1121 O O   . THR A 1 142 ? 19.83280  1.32307  -14.83159 1.000 28.08638 ? 142 THR A O   1 
ATOM   1122 C CB  . THR A 1 142 ? 22.70696  2.15217  -15.49778 1.000 29.34635 ? 142 THR A CB  1 
ATOM   1123 O OG1 . THR A 1 142 ? 22.24668  3.51093  -15.43198 1.000 29.01851 ? 142 THR A OG1 1 
ATOM   1124 C CG2 . THR A 1 142 ? 24.10692  2.09473  -16.10584 1.000 25.34314 ? 142 THR A CG2 1 
ATOM   1125 N N   . ASN A 1 143 ? 19.55809  2.32400  -16.82925 1.000 28.90201 ? 143 ASN A N   1 
ATOM   1126 C CA  . ASN A 1 143 ? 18.21419  2.80802  -16.52519 1.000 27.12397 ? 143 ASN A CA  1 
ATOM   1127 C C   . ASN A 1 143 ? 17.15893  1.90650  -17.16371 1.000 28.54231 ? 143 ASN A C   1 
ATOM   1128 O O   . ASN A 1 143 ? 16.30426  2.33591  -17.94261 1.000 27.38478 ? 143 ASN A O   1 
ATOM   1129 C CB  . ASN A 1 143 ? 18.06401  4.25096  -16.98350 1.000 23.45091 ? 143 ASN A CB  1 
ATOM   1130 C CG  . ASN A 1 143 ? 18.84164  5.20551  -16.10712 1.000 23.66011 ? 143 ASN A CG  1 
ATOM   1131 O OD1 . ASN A 1 143 ? 18.83546  5.09226  -14.87610 1.000 26.02788 ? 143 ASN A OD1 1 
ATOM   1132 N ND2 . ASN A 1 143 ? 19.52613  6.14682  -16.73295 1.000 30.41544 ? 143 ASN A ND2 1 
ATOM   1133 N N   . VAL A 1 144 ? 17.22740  0.62793  -16.80873 1.000 24.73040 ? 144 VAL A N   1 
ATOM   1134 C CA  . VAL A 1 144 ? 16.25647  -0.37096 -17.23701 1.000 29.42174 ? 144 VAL A CA  1 
ATOM   1135 C C   . VAL A 1 144 ? 15.90252  -1.19332 -16.00692 1.000 32.45753 ? 144 VAL A C   1 
ATOM   1136 O O   . VAL A 1 144 ? 16.75871  -1.90325 -15.46212 1.000 35.66651 ? 144 VAL A O   1 
ATOM   1137 C CB  . VAL A 1 144 ? 16.79424  -1.26753 -18.36090 1.000 31.22594 ? 144 VAL A CB  1 
ATOM   1138 C CG1 . VAL A 1 144 ? 15.78405  -2.35716 -18.69199 1.000 29.09366 ? 144 VAL A CG1 1 
ATOM   1139 C CG2 . VAL A 1 144 ? 17.11625  -0.43579 -19.59128 1.000 25.63027 ? 144 VAL A CG2 1 
ATOM   1140 N N   . ASP A 1 145 ? 14.65150  -1.09926 -15.56732 1.000 33.66232 ? 145 ASP A N   1 
ATOM   1141 C CA  . ASP A 1 145 ? 14.24790  -1.74799 -14.33153 1.000 32.16115 ? 145 ASP A CA  1 
ATOM   1142 C C   . ASP A 1 145 ? 14.23144  -3.25988 -14.52302 1.000 38.76079 ? 145 ASP A C   1 
ATOM   1143 O O   . ASP A 1 145 ? 14.03933  -3.76114 -15.63430 1.000 42.39484 ? 145 ASP A O   1 
ATOM   1144 C CB  . ASP A 1 145 ? 12.87858  -1.23087 -13.88683 1.000 26.89273 ? 145 ASP A CB  1 
ATOM   1145 C CG  . ASP A 1 145 ? 12.46431  -1.75628 -12.52311 1.000 35.61765 ? 145 ASP A CG  1 
ATOM   1146 O OD1 . ASP A 1 145 ? 13.19319  -1.49321 -11.54420 1.000 39.09137 ? 145 ASP A OD1 1 
ATOM   1147 O OD2 . ASP A 1 145 ? 11.40416  -2.40750 -12.42155 1.000 39.54762 ? 145 ASP A OD2 1 
ATOM   1148 N N   . VAL A 1 146 ? 14.44544  -3.97662 -13.41817 1.000 43.94288 ? 146 VAL A N   1 
ATOM   1149 C CA  . VAL A 1 146 ? 14.67534  -5.42647 -13.39062 1.000 43.86854 ? 146 VAL A CA  1 
ATOM   1150 C C   . VAL A 1 146 ? 16.04043  -5.70962 -14.01116 1.000 46.10023 ? 146 VAL A C   1 
ATOM   1151 O O   . VAL A 1 146 ? 17.06491  -5.21283 -13.53392 1.000 46.03658 ? 146 VAL A O   1 
ATOM   1152 C CB  . VAL A 1 146 ? 13.56118  -6.23333 -14.10733 1.000 43.55246 ? 146 VAL A CB  1 
ATOM   1153 C CG1 . VAL A 1 146 ? 14.16924  -7.39909 -14.89846 1.000 40.85312 ? 146 VAL A CG1 1 
ATOM   1154 C CG2 . VAL A 1 146 ? 12.51660  -6.72152 -13.11122 1.000 42.18720 ? 146 VAL A CG2 1 
ATOM   1155 N N   . PRO B 1 1   ? -10.77218 21.52360 -19.40957 1.000 15.89149 ? 1   PRO B N   1 
ATOM   1156 C CA  . PRO B 1 1   ? -9.35884  21.87926 -19.60457 1.000 14.59402 ? 1   PRO B CA  1 
ATOM   1157 C C   . PRO B 1 1   ? -8.52186  21.49747 -18.43470 1.000 11.63932 ? 1   PRO B C   1 
ATOM   1158 O O   . PRO B 1 1   ? -9.07509  21.19220 -17.38858 1.000 9.91654  ? 1   PRO B O   1 
ATOM   1159 C CB  . PRO B 1 1   ? -9.39390  23.40343 -19.73633 1.000 15.75996 ? 1   PRO B CB  1 
ATOM   1160 C CG  . PRO B 1 1   ? -10.62863 23.81129 -19.02218 1.000 18.53118 ? 1   PRO B CG  1 
ATOM   1161 C CD  . PRO B 1 1   ? -11.62345 22.71984 -19.32247 1.000 15.42510 ? 1   PRO B CD  1 
ATOM   1162 N N   . VAL B 1 2   ? -7.20541  21.54501 -18.58266 1.000 9.78691  ? 2   VAL B N   1 
ATOM   1163 C CA  . VAL B 1 2   ? -6.31939  21.58065 -17.42934 1.000 7.50903  ? 2   VAL B CA  1 
ATOM   1164 C C   . VAL B 1 2   ? -5.56259  22.89367 -17.48540 1.000 9.38242  ? 2   VAL B C   1 
ATOM   1165 O O   . VAL B 1 2   ? -4.84806  23.16935 -18.46169 1.000 9.75016  ? 2   VAL B O   1 
ATOM   1166 C CB  . VAL B 1 2   ? -5.34716  20.39396 -17.39394 1.000 6.96148  ? 2   VAL B CB  1 
ATOM   1167 C CG1 . VAL B 1 2   ? -4.38543  20.56088 -16.20953 1.000 10.09568 ? 2   VAL B CG1 1 
ATOM   1168 C CG2 . VAL B 1 2   ? -6.11345  19.07812 -17.24576 1.000 10.51295 ? 2   VAL B CG2 1 
ATOM   1169 N N   . TYR B 1 3   ? -5.72037  23.69704 -16.44303 1.000 8.24416  ? 3   TYR B N   1 
ATOM   1170 C CA  . TYR B 1 3   ? -4.98435  24.94285 -16.25828 1.000 7.97631  ? 3   TYR B CA  1 
ATOM   1171 C C   . TYR B 1 3   ? -3.95375  24.70756 -15.16761 1.000 8.11573  ? 3   TYR B C   1 
ATOM   1172 O O   . TYR B 1 3   ? -4.30610  24.54992 -13.99148 1.000 9.83185  ? 3   TYR B O   1 
ATOM   1173 C CB  . TYR B 1 3   ? -5.91090  26.09087 -15.87158 1.000 8.34403  ? 3   TYR B CB  1 
ATOM   1174 C CG  . TYR B 1 3   ? -6.74779  26.57376 -17.01366 1.000 10.05548 ? 3   TYR B CG  1 
ATOM   1175 C CD1 . TYR B 1 3   ? -6.22309  27.47059 -17.93256 1.000 8.96682  ? 3   TYR B CD1 1 
ATOM   1176 C CD2 . TYR B 1 3   ? -8.07639  26.16412 -17.15822 1.000 10.47600 ? 3   TYR B CD2 1 
ATOM   1177 C CE1 . TYR B 1 3   ? -6.96516  27.92510 -18.98018 1.000 9.20437  ? 3   TYR B CE1 1 
ATOM   1178 C CE2 . TYR B 1 3   ? -8.85213  26.63398 -18.22256 1.000 10.65133 ? 3   TYR B CE2 1 
ATOM   1179 C CZ  . TYR B 1 3   ? -8.27538  27.52575 -19.12630 1.000 11.58690 ? 3   TYR B CZ  1 
ATOM   1180 O OH  . TYR B 1 3   ? -8.99603  28.01556 -20.20490 1.000 11.29476 ? 3   TYR B OH  1 
ATOM   1181 N N   . MET B 1 4   ? -2.68678  24.66977 -15.55981 1.000 6.66975  ? 4   MET B N   1 
ATOM   1182 C CA  . MET B 1 4   ? -1.59140  24.52833 -14.62523 1.000 8.80889  ? 4   MET B CA  1 
ATOM   1183 C C   . MET B 1 4   ? -1.24276  25.94900 -14.18800 1.000 8.25983  ? 4   MET B C   1 
ATOM   1184 O O   . MET B 1 4   ? -1.00903  26.81102 -15.03855 1.000 10.11592 ? 4   MET B O   1 
ATOM   1185 C CB  . MET B 1 4   ? -0.39741  23.84809 -15.30172 1.000 8.67494  ? 4   MET B CB  1 
ATOM   1186 C CG  . MET B 1 4   ? -0.70322  22.42326 -15.80253 1.000 9.71884  ? 4   MET B CG  1 
ATOM   1187 S SD  . MET B 1 4   ? -1.26282  21.22290 -14.63495 1.000 10.13506 ? 4   MET B SD  1 
ATOM   1188 C CE  . MET B 1 4   ? 0.15780   21.11816 -13.51215 1.000 12.77382 ? 4   MET B CE  1 
ATOM   1189 N N   . VAL B 1 5   ? -1.25807  26.22878 -12.88946 1.000 7.19359  ? 5   VAL B N   1 
ATOM   1190 C CA  . VAL B 1 5   ? -1.08690  27.60528 -12.41510 1.000 6.42247  ? 5   VAL B CA  1 
ATOM   1191 C C   . VAL B 1 5   ? 0.14124   27.64590 -11.51359 1.000 8.74373  ? 5   VAL B C   1 
ATOM   1192 O O   . VAL B 1 5   ? 0.11435   27.13181 -10.38797 1.000 10.08661 ? 5   VAL B O   1 
ATOM   1193 C CB  . VAL B 1 5   ? -2.33021  28.12487 -11.68690 1.000 7.64093  ? 5   VAL B CB  1 
ATOM   1194 C CG1 . VAL B 1 5   ? -2.12505  29.60116 -11.32843 1.000 9.81763  ? 5   VAL B CG1 1 
ATOM   1195 C CG2 . VAL B 1 5   ? -3.55679  27.97182 -12.57046 1.000 11.36865 ? 5   VAL B CG2 1 
ATOM   1196 N N   . TYR B 1 6   ? 1.20707   28.27743 -11.99902 1.000 7.17252  ? 6   TYR B N   1 
ATOM   1197 C CA  . TYR B 1 6   ? 2.50189   28.28340 -11.33254 1.000 7.96574  ? 6   TYR B CA  1 
ATOM   1198 C C   . TYR B 1 6   ? 2.64818   29.55891 -10.52110 1.000 7.61788  ? 6   TYR B C   1 
ATOM   1199 O O   . TYR B 1 6   ? 2.69284   30.65109 -11.08274 1.000 9.47938  ? 6   TYR B O   1 
ATOM   1200 C CB  . TYR B 1 6   ? 3.63151   28.15506 -12.35076 1.000 7.85208  ? 6   TYR B CB  1 
ATOM   1201 C CG  . TYR B 1 6   ? 3.50258   26.89564 -13.13293 1.000 7.99761  ? 6   TYR B CG  1 
ATOM   1202 C CD1 . TYR B 1 6   ? 3.98583   25.69518 -12.63141 1.000 8.74436  ? 6   TYR B CD1 1 
ATOM   1203 C CD2 . TYR B 1 6   ? 2.86040   26.88332 -14.36590 1.000 8.17891  ? 6   TYR B CD2 1 
ATOM   1204 C CE1 . TYR B 1 6   ? 3.86914   24.51787 -13.34776 1.000 7.71293  ? 6   TYR B CE1 1 
ATOM   1205 C CE2 . TYR B 1 6   ? 2.71656   25.70416 -15.08957 1.000 10.21848 ? 6   TYR B CE2 1 
ATOM   1206 C CZ  . TYR B 1 6   ? 3.21528   24.52449 -14.56236 1.000 9.55597  ? 6   TYR B CZ  1 
ATOM   1207 O OH  . TYR B 1 6   ? 3.08416   23.36031 -15.26872 1.000 10.25308 ? 6   TYR B OH  1 
ATOM   1208 N N   . VAL B 1 7   ? 2.72390   29.41182 -9.20097  1.000 7.72342  ? 7   VAL B N   1 
ATOM   1209 C CA  . VAL B 1 7   ? 2.76627   30.54665 -8.29062  1.000 9.25357  ? 7   VAL B CA  1 
ATOM   1210 C C   . VAL B 1 7   ? 3.82226   30.28122 -7.22943  1.000 9.20052  ? 7   VAL B C   1 
ATOM   1211 O O   . VAL B 1 7   ? 4.26359   29.15028 -7.02278  1.000 10.86519 ? 7   VAL B O   1 
ATOM   1212 C CB  . VAL B 1 7   ? 1.39725   30.80175 -7.61157  1.000 11.64884 ? 7   VAL B CB  1 
ATOM   1213 C CG1 . VAL B 1 7   ? 0.35746   31.23671 -8.64372  1.000 11.52360 ? 7   VAL B CG1 1 
ATOM   1214 C CG2 . VAL B 1 7   ? 0.92898   29.56231 -6.89061  1.000 10.33916 ? 7   VAL B CG2 1 
ATOM   1215 N N   . SER B 1 8   ? 4.19410   31.34623 -6.53676  1.000 10.77546 ? 8   SER B N   1 
ATOM   1216 C CA  . SER B 1 8   ? 5.10721   31.22473 -5.41328  1.000 9.37084  ? 8   SER B CA  1 
ATOM   1217 C C   . SER B 1 8   ? 4.37462   30.79589 -4.14467  1.000 10.65498 ? 8   SER B C   1 
ATOM   1218 O O   . SER B 1 8   ? 3.24017   31.21226 -3.88209  1.000 12.65836 ? 8   SER B O   1 
ATOM   1219 C CB  . SER B 1 8   ? 5.83109   32.54750 -5.18978  1.000 12.46159 ? 8   SER B CB  1 
ATOM   1220 O OG  . SER B 1 8   ? 6.67817   32.82753 -6.28564  1.000 15.24031 ? 8   SER B OG  1 
ATOM   1221 N N   . GLN B 1 9   ? 5.05789   29.97927 -3.34586  1.000 11.76734 ? 9   GLN B N   1 
ATOM   1222 C CA  . GLN B 1 9   ? 4.54164   29.54976 -2.05823  1.000 13.91394 ? 9   GLN B CA  1 
ATOM   1223 C C   . GLN B 1 9   ? 4.07554   30.75070 -1.24652  1.000 17.47405 ? 9   GLN B C   1 
ATOM   1224 O O   . GLN B 1 9   ? 4.77815   31.76307 -1.14510  1.000 16.86795 ? 9   GLN B O   1 
ATOM   1225 C CB  . GLN B 1 9   ? 5.62652   28.77613 -1.29727  1.000 14.87903 ? 9   GLN B CB  1 
ATOM   1226 C CG  . GLN B 1 9   ? 5.11934   28.19064 0.01686   1.000 14.97163 ? 9   GLN B CG  1 
ATOM   1227 C CD  . GLN B 1 9   ? 4.15048   27.05942 -0.21313  1.000 19.75384 ? 9   GLN B CD  1 
ATOM   1228 O OE1 . GLN B 1 9   ? 4.37943   26.20771 -1.06770  1.000 17.69910 ? 9   GLN B OE1 1 
ATOM   1229 N NE2 . GLN B 1 9   ? 3.03592   27.06170 0.52061   1.000 20.34684 ? 9   GLN B NE2 1 
ATOM   1230 N N   . ASP B 1 10  ? 2.85948   30.63879 -0.71949  1.000 19.59740 ? 10  ASP B N   1 
ATOM   1231 C CA  . ASP B 1 10  ? 2.22384   31.58161 0.18872   1.000 22.06896 ? 10  ASP B CA  1 
ATOM   1232 C C   . ASP B 1 10  ? 1.81405   32.88163 -0.48535  1.000 22.90790 ? 10  ASP B C   1 
ATOM   1233 O O   . ASP B 1 10  ? 1.31998   33.78453 0.19941   1.000 24.14845 ? 10  ASP B O   1 
ATOM   1234 C CB  . ASP B 1 10  ? 3.11738   31.90422 1.39423   1.000 24.32250 ? 10  ASP B CB  1 
ATOM   1235 C CG  . ASP B 1 10  ? 3.24500   30.72990 2.34150   1.000 31.31079 ? 10  ASP B CG  1 
ATOM   1236 O OD1 . ASP B 1 10  ? 2.40397   29.80188 2.26262   1.000 30.18335 ? 10  ASP B OD1 1 
ATOM   1237 O OD2 . ASP B 1 10  ? 4.18629   30.73758 3.16290   1.000 42.07114 ? 10  ASP B OD2 1 
ATOM   1238 N N   . ARG B 1 11  ? 1.98259   33.02167 -1.79814  1.000 17.17739 ? 11  ARG B N   1 
ATOM   1239 C CA  . ARG B 1 11  ? 1.44790   34.22669 -2.41685  1.000 17.94435 ? 11  ARG B CA  1 
ATOM   1240 C C   . ARG B 1 11  ? -0.07742  34.17593 -2.46782  1.000 13.51611 ? 11  ARG B C   1 
ATOM   1241 O O   . ARG B 1 11  ? -0.73503  35.21356 -2.32057  1.000 20.83540 ? 11  ARG B O   1 
ATOM   1242 C CB  . ARG B 1 11  ? 2.03888   34.43394 -3.80916  1.000 16.14295 ? 11  ARG B CB  1 
ATOM   1243 C CG  . ARG B 1 11  ? 1.27396   35.43667 -4.63400  1.000 18.68680 ? 11  ARG B CG  1 
ATOM   1244 C CD  . ARG B 1 11  ? 1.67320   36.84646 -4.20767  1.000 20.51314 ? 11  ARG B CD  1 
ATOM   1245 N NE  . ARG B 1 11  ? 0.97635   37.90024 -4.94363  1.000 25.54435 ? 11  ARG B NE  1 
ATOM   1246 C CZ  . ARG B 1 11  ? -0.31906  38.18118 -4.85085  1.000 26.09170 ? 11  ARG B CZ  1 
ATOM   1247 N NH1 . ARG B 1 11  ? -1.12390  37.50532 -4.04495  1.000 25.59878 ? 11  ARG B NH1 1 
ATOM   1248 N NH2 . ARG B 1 11  ? -0.81909  39.17904 -5.57614  1.000 29.34333 ? 11  ARG B NH2 1 
ATOM   1249 N N   . LEU B 1 12  ? -0.65705  32.98423 -2.60381  1.000 14.52498 ? 12  LEU B N   1 
ATOM   1250 C CA  . LEU B 1 12  ? -2.10755  32.81296 -2.57092  1.000 17.34243 ? 12  LEU B CA  1 
ATOM   1251 C C   . LEU B 1 12  ? -2.50065  32.03936 -1.31790  1.000 17.55984 ? 12  LEU B C   1 
ATOM   1252 O O   . LEU B 1 12  ? -2.06959  30.89822 -1.12530  1.000 19.83903 ? 12  LEU B O   1 
ATOM   1253 C CB  . LEU B 1 12  ? -2.60866  32.08808 -3.82307  1.000 20.28980 ? 12  LEU B CB  1 
ATOM   1254 C CG  . LEU B 1 12  ? -2.28618  32.74938 -5.16660  1.000 18.58311 ? 12  LEU B CG  1 
ATOM   1255 C CD1 . LEU B 1 12  ? -2.79250  31.91494 -6.32445  1.000 16.29533 ? 12  LEU B CD1 1 
ATOM   1256 C CD2 . LEU B 1 12  ? -2.81959  34.15830 -5.26644  1.000 17.96139 ? 12  LEU B CD2 1 
ATOM   1257 N N   . THR B 1 13  ? -3.33523  32.65799 -0.47925  1.000 19.28011 ? 13  THR B N   1 
ATOM   1258 C CA  . THR B 1 13  ? -3.97410  31.95234 0.61659   1.000 19.43876 ? 13  THR B CA  1 
ATOM   1259 C C   . THR B 1 13  ? -4.92506  30.88483 0.07773   1.000 15.60344 ? 13  THR B C   1 
ATOM   1260 O O   . THR B 1 13  ? -5.26546  30.88929 -1.10735  1.000 16.93736 ? 13  THR B O   1 
ATOM   1261 C CB  . THR B 1 13  ? -4.74493  32.94465 1.48279   1.000 18.93296 ? 13  THR B CB  1 
ATOM   1262 O OG1 . THR B 1 13  ? -5.74530  33.59328 0.68054   1.000 18.83510 ? 13  THR B OG1 1 
ATOM   1263 C CG2 . THR B 1 13  ? -3.80196  33.98637 2.09177   1.000 23.27516 ? 13  THR B CG2 1 
ATOM   1264 N N   . PRO B 1 14  ? -5.35299  29.93939 0.92156   1.000 20.91175 ? 14  PRO B N   1 
ATOM   1265 C CA  . PRO B 1 14  ? -6.42420  29.03116 0.48682   1.000 18.23219 ? 14  PRO B CA  1 
ATOM   1266 C C   . PRO B 1 14  ? -7.61995  29.77228 -0.09808  1.000 16.26533 ? 14  PRO B C   1 
ATOM   1267 O O   . PRO B 1 14  ? -8.17293  29.34720 -1.11748  1.000 14.20761 ? 14  PRO B O   1 
ATOM   1268 C CB  . PRO B 1 14  ? -6.76027  28.27301 1.77783   1.000 23.18165 ? 14  PRO B CB  1 
ATOM   1269 C CG  . PRO B 1 14  ? -5.44055  28.22612 2.49716   1.000 25.36481 ? 14  PRO B CG  1 
ATOM   1270 C CD  . PRO B 1 14  ? -4.84915  29.58615 2.26584   1.000 20.63644 ? 14  PRO B CD  1 
ATOM   1271 N N   . SER B 1 15  ? -8.00479  30.90491 0.48487   1.000 15.88154 ? 15  SER B N   1 
ATOM   1272 C CA  . SER B 1 15  ? -9.14772  31.63641 -0.05844  1.000 16.55799 ? 15  SER B CA  1 
ATOM   1273 C C   . SER B 1 15  ? -8.82270  32.22374 -1.42624  1.000 14.92337 ? 15  SER B C   1 
ATOM   1274 O O   . SER B 1 15  ? -9.64307  32.14739 -2.34903  1.000 14.01682 ? 15  SER B O   1 
ATOM   1275 C CB  . SER B 1 15  ? -9.59352  32.72874 0.91793   1.000 17.82790 ? 15  SER B CB  1 
ATOM   1276 O OG  . SER B 1 15  ? -10.56920 33.55541 0.31107   1.000 23.53008 ? 15  SER B OG  1 
ATOM   1277 N N   . ALA B 1 16  ? -7.61187  32.76462 -1.59753  1.000 15.76889 ? 16  ALA B N   1 
ATOM   1278 C CA  . ALA B 1 16  ? -7.25935  33.34211 -2.89008  1.000 12.23123 ? 16  ALA B CA  1 
ATOM   1279 C C   . ALA B 1 16  ? -7.10925  32.26473 -3.95730  1.000 12.68272 ? 16  ALA B C   1 
ATOM   1280 O O   . ALA B 1 16  ? -7.42953  32.50566 -5.12683  1.000 12.73227 ? 16  ALA B O   1 
ATOM   1281 C CB  . ALA B 1 16  ? -5.97794  34.16747 -2.77869  1.000 15.69709 ? 16  ALA B CB  1 
ATOM   1282 N N   . LYS B 1 17  ? -6.58688  31.08787 -3.58649  1.000 13.54695 ? 17  LYS B N   1 
ATOM   1283 C CA  . LYS B 1 17  ? -6.52600  29.98308 -4.54043  1.000 11.22680 ? 17  LYS B CA  1 
ATOM   1284 C C   . LYS B 1 17  ? -7.91756  29.61236 -5.02016  1.000 14.59761 ? 17  LYS B C   1 
ATOM   1285 O O   . LYS B 1 17  ? -8.13657  29.38369 -6.21225  1.000 11.63095 ? 17  LYS B O   1 
ATOM   1286 C CB  . LYS B 1 17  ? -5.85646  28.76250 -3.91279  1.000 15.32352 ? 17  LYS B CB  1 
ATOM   1287 C CG  . LYS B 1 17  ? -4.35629  28.87140 -3.75690  1.000 17.41327 ? 17  LYS B CG  1 
ATOM   1288 C CD  . LYS B 1 17  ? -3.87541  27.57246 -3.15293  1.000 17.40941 ? 17  LYS B CD  1 
ATOM   1289 C CE  . LYS B 1 17  ? -2.46978  27.67345 -2.64038  1.000 23.99881 ? 17  LYS B CE  1 
ATOM   1290 N NZ  . LYS B 1 17  ? -2.25384  26.54672 -1.69152  1.000 21.37041 ? 17  LYS B NZ  1 
ATOM   1291 N N   . HIS B 1 18  ? -8.86606  29.50026 -4.08952  1.000 11.24714 ? 18  HIS B N   1 
ATOM   1292 C CA  . HIS B 1 18  ? -10.23909 29.22216 -4.47844  1.000 11.72479 ? 18  HIS B CA  1 
ATOM   1293 C C   . HIS B 1 18  ? -10.75985 30.28022 -5.44043  1.000 11.44959 ? 18  HIS B C   1 
ATOM   1294 O O   . HIS B 1 18  ? -11.38571 29.95561 -6.45610  1.000 11.91972 ? 18  HIS B O   1 
ATOM   1295 C CB  . HIS B 1 18  ? -11.12417 29.17215 -3.23595  1.000 12.25923 ? 18  HIS B CB  1 
ATOM   1296 C CG  . HIS B 1 18  ? -12.44070 28.50898 -3.46227  1.000 16.78252 ? 18  HIS B CG  1 
ATOM   1297 N ND1 . HIS B 1 18  ? -13.31011 28.21999 -2.43176  1.000 20.25788 ? 18  HIS B ND1 1 
ATOM   1298 C CD2 . HIS B 1 18  ? -13.00140 27.99582 -4.58321  1.000 18.84097 ? 18  HIS B CD2 1 
ATOM   1299 C CE1 . HIS B 1 18  ? -14.38176 27.62089 -2.92114  1.000 23.07516 ? 18  HIS B CE1 1 
ATOM   1300 N NE2 . HIS B 1 18  ? -14.21700 27.46626 -4.22273  1.000 19.13683 ? 18  HIS B NE2 1 
ATOM   1301 N N   . ALA B 1 19  ? -10.52098 31.56225 -5.12456  1.000 11.20120 ? 19  ALA B N   1 
ATOM   1302 C CA  . ALA B 1 19  ? -11.03543 32.64654 -5.95621  1.000 9.98992  ? 19  ALA B CA  1 
ATOM   1303 C C   . ALA B 1 19  ? -10.40520 32.63363 -7.34434  1.000 9.87963  ? 19  ALA B C   1 
ATOM   1304 O O   . ALA B 1 19  ? -11.08573 32.89560 -8.34524  1.000 11.05806 ? 19  ALA B O   1 
ATOM   1305 C CB  . ALA B 1 19  ? -10.78640 33.98949 -5.26275  1.000 12.53607 ? 19  ALA B CB  1 
ATOM   1306 N N   . VAL B 1 20  ? -9.10503  32.33486 -7.42184  1.000 10.92982 ? 20  VAL B N   1 
ATOM   1307 C CA  . VAL B 1 20  ? -8.43498  32.23475 -8.71422  1.000 9.84305  ? 20  VAL B CA  1 
ATOM   1308 C C   . VAL B 1 20  ? -8.97175  31.04972 -9.50545  1.000 8.76708  ? 20  VAL B C   1 
ATOM   1309 O O   . VAL B 1 20  ? -9.22572  31.15894 -10.71324 1.000 10.60405 ? 20  VAL B O   1 
ATOM   1310 C CB  . VAL B 1 20  ? -6.91151  32.13840 -8.50713  1.000 9.58382  ? 20  VAL B CB  1 
ATOM   1311 C CG1 . VAL B 1 20  ? -6.22290  31.70646 -9.80917  1.000 11.92855 ? 20  VAL B CG1 1 
ATOM   1312 C CG2 . VAL B 1 20  ? -6.36148  33.47512 -8.03312  1.000 10.94218 ? 20  VAL B CG2 1 
ATOM   1313 N N   . ALA B 1 21  ? -9.15882  29.90444 -8.84293  1.000 8.86059  ? 21  ALA B N   1 
ATOM   1314 C CA  . ALA B 1 21  ? -9.68672  28.73445 -9.53438  1.000 8.99112  ? 21  ALA B CA  1 
ATOM   1315 C C   . ALA B 1 21  ? -11.09395 28.99589 -10.05743 1.000 12.23745 ? 21  ALA B C   1 
ATOM   1316 O O   . ALA B 1 21  ? -11.41326 28.63533 -11.19613 1.000 12.86467 ? 21  ALA B O   1 
ATOM   1317 C CB  . ALA B 1 21  ? -9.64903  27.51765 -8.61186  1.000 10.10722 ? 21  ALA B CB  1 
ATOM   1318 N N   . LYS B 1 22  ? -11.94464 29.64155 -9.25000  1.000 12.39086 ? 22  LYS B N   1 
ATOM   1319 C CA  . LYS B 1 22  ? -13.27931 29.98456 -9.73346  1.000 11.67002 ? 22  LYS B CA  1 
ATOM   1320 C C   . LYS B 1 22  ? -13.22320 30.99053 -10.87452 1.000 11.47825 ? 22  LYS B C   1 
ATOM   1321 O O   . LYS B 1 22  ? -14.01535 30.90040 -11.82127 1.000 12.39810 ? 22  LYS B O   1 
ATOM   1322 C CB  . LYS B 1 22  ? -14.15725 30.50893 -8.58870  1.000 13.75573 ? 22  LYS B CB  1 
ATOM   1323 C CG  . LYS B 1 22  ? -14.45826 29.47317 -7.51609  1.000 17.16055 ? 22  LYS B CG  1 
ATOM   1324 C CD  . LYS B 1 22  ? -15.21452 30.12194 -6.35627  1.000 21.02354 ? 22  LYS B CD  1 
ATOM   1325 C CE  . LYS B 1 22  ? -16.56714 30.62800 -6.81022  1.000 32.43661 ? 22  LYS B CE  1 
ATOM   1326 N NZ  . LYS B 1 22  ? -17.05031 31.70585 -5.89942  1.000 45.74472 ? 22  LYS B NZ  1 
ATOM   1327 N N   . ALA B 1 23  ? -12.30037 31.95461 -10.81718 1.000 11.81791 ? 23  ALA B N   1 
ATOM   1328 C CA  . ALA B 1 23  ? -12.20703 32.92697 -11.90484 1.000 9.54895  ? 23  ALA B CA  1 
ATOM   1329 C C   . ALA B 1 23  ? -11.82844 32.24633 -13.20924 1.000 11.77822 ? 23  ALA B C   1 
ATOM   1330 O O   . ALA B 1 23  ? -12.41036 32.53423 -14.26300 1.000 11.64309 ? 23  ALA B O   1 
ATOM   1331 C CB  . ALA B 1 23  ? -11.19837 34.02468 -11.56521 1.000 14.22539 ? 23  ALA B CB  1 
ATOM   1332 N N   . ILE B 1 24  ? -10.86018 31.33519 -13.15537 1.000 10.27985 ? 24  ILE B N   1 
ATOM   1333 C CA  . ILE B 1 24  ? -10.43679 30.64103 -14.36905 1.000 9.55509  ? 24  ILE B CA  1 
ATOM   1334 C C   . ILE B 1 24  ? -11.54960 29.74203 -14.88243 1.000 11.72054 ? 24  ILE B C   1 
ATOM   1335 O O   . ILE B 1 24  ? -11.84233 29.73203 -16.07951 1.000 10.56409 ? 24  ILE B O   1 
ATOM   1336 C CB  . ILE B 1 24  ? -9.13977  29.85927 -14.11219 1.000 9.05227  ? 24  ILE B CB  1 
ATOM   1337 C CG1 . ILE B 1 24  ? -7.98223  30.83238 -13.92950 1.000 9.35737  ? 24  ILE B CG1 1 
ATOM   1338 C CG2 . ILE B 1 24  ? -8.84724  28.95390 -15.29060 1.000 9.98744  ? 24  ILE B CG2 1 
ATOM   1339 C CD1 . ILE B 1 24  ? -6.68486  30.16477 -13.46278 1.000 9.43574  ? 24  ILE B CD1 1 
ATOM   1340 N N   . THR B 1 25  ? -12.20812 29.00682 -13.97582 1.000 9.94725  ? 25  THR B N   1 
ATOM   1341 C CA  . THR B 1 25  ? -13.30000 28.10549 -14.33352 1.000 8.88772  ? 25  THR B CA  1 
ATOM   1342 C C   . THR B 1 25  ? -14.46376 28.86330 -14.95935 1.000 10.52824 ? 25  THR B C   1 
ATOM   1343 O O   . THR B 1 25  ? -15.02611 28.43534 -15.97472 1.000 12.52642 ? 25  THR B O   1 
ATOM   1344 C CB  . THR B 1 25  ? -13.76415 27.36316 -13.07391 1.000 12.20178 ? 25  THR B CB  1 
ATOM   1345 O OG1 . THR B 1 25  ? -12.65773 26.65894 -12.50310 1.000 13.02005 ? 25  THR B OG1 1 
ATOM   1346 C CG2 . THR B 1 25  ? -14.89360 26.37943 -13.38648 1.000 13.97354 ? 25  THR B CG2 1 
ATOM   1347 N N   . ASP B 1 26  ? -14.86283 29.97568 -14.33423 1.000 13.34075 ? 26  ASP B N   1 
ATOM   1348 C CA  . ASP B 1 26  ? -15.97860 30.77225 -14.84536 1.000 15.87774 ? 26  ASP B CA  1 
ATOM   1349 C C   . ASP B 1 26  ? -15.65699 31.36902 -16.21144 1.000 13.84255 ? 26  ASP B C   1 
ATOM   1350 O O   . ASP B 1 26  ? -16.53763 31.46477 -17.07433 1.000 14.00192 ? 26  ASP B O   1 
ATOM   1351 C CB  . ASP B 1 26  ? -16.32902 31.88840 -13.85413 1.000 13.85326 ? 26  ASP B CB  1 
ATOM   1352 C CG  . ASP B 1 26  ? -16.95704 31.37076 -12.58789 1.000 18.77300 ? 26  ASP B CG  1 
ATOM   1353 O OD1 . ASP B 1 26  ? -17.29130 30.17375 -12.53185 1.000 19.23855 ? 26  ASP B OD1 1 
ATOM   1354 O OD2 . ASP B 1 26  ? -17.09403 32.17084 -11.63710 1.000 22.59113 ? 26  ASP B OD2 1 
ATOM   1355 N N   . ALA B 1 27  ? -14.40293 31.78083 -16.43021 1.000 11.55465 ? 27  ALA B N   1 
ATOM   1356 C CA  . ALA B 1 27  ? -14.02287 32.31376 -17.73664 1.000 12.48112 ? 27  ALA B CA  1 
ATOM   1357 C C   . ALA B 1 27  ? -14.12329 31.24430 -18.81242 1.000 13.61717 ? 27  ALA B C   1 
ATOM   1358 O O   . ALA B 1 27  ? -14.62523 31.49319 -19.91647 1.000 11.60602 ? 27  ALA B O   1 
ATOM   1359 C CB  . ALA B 1 27  ? -12.59612 32.86633 -17.67919 1.000 11.39948 ? 27  ALA B CB  1 
ATOM   1360 N N   . HIS B 1 28  ? -13.63176 30.05299 -18.51011 1.000 10.41184 ? 28  HIS B N   1 
ATOM   1361 C CA  . HIS B 1 28  ? -13.64481 28.97762 -19.48732 1.000 10.42419 ? 28  HIS B CA  1 
ATOM   1362 C C   . HIS B 1 28  ? -15.07271 28.55045 -19.80399 1.000 13.73008 ? 28  HIS B C   1 
ATOM   1363 O O   . HIS B 1 28  ? -15.43166 28.38783 -20.97258 1.000 12.80809 ? 28  HIS B O   1 
ATOM   1364 C CB  . HIS B 1 28  ? -12.83104 27.79391 -18.96880 1.000 10.90360 ? 28  HIS B CB  1 
ATOM   1365 C CG  . HIS B 1 28  ? -12.51095 26.80618 -20.04151 1.000 10.02140 ? 28  HIS B CG  1 
ATOM   1366 N ND1 . HIS B 1 28  ? -11.34698 26.87955 -20.77058 1.000 11.51885 ? 28  HIS B ND1 1 
ATOM   1367 C CD2 . HIS B 1 28  ? -13.21147 25.76485 -20.54970 1.000 16.51340 ? 28  HIS B CD2 1 
ATOM   1368 C CE1 . HIS B 1 28  ? -11.32728 25.90913 -21.66495 1.000 13.31779 ? 28  HIS B CE1 1 
ATOM   1369 N NE2 . HIS B 1 28  ? -12.45279 25.22672 -21.56087 1.000 14.38700 ? 28  HIS B NE2 1 
ATOM   1370 N N   . ARG B 1 29  ? -15.91033 28.37822 -18.77616 1.000 12.81696 ? 29  ARG B N   1 
ATOM   1371 C CA  . ARG B 1 29  ? -17.29302 27.98534 -19.04773 1.000 14.41452 ? 29  ARG B CA  1 
ATOM   1372 C C   . ARG B 1 29  ? -18.04336 29.09015 -19.77871 1.000 16.43851 ? 29  ARG B C   1 
ATOM   1373 O O   . ARG B 1 29  ? -18.81086 28.81870 -20.71316 1.000 17.47056 ? 29  ARG B O   1 
ATOM   1374 C CB  . ARG B 1 29  ? -18.02747 27.63589 -17.76095 1.000 20.25978 ? 29  ARG B CB  1 
ATOM   1375 C CG  . ARG B 1 29  ? -19.46712 27.21553 -18.05412 1.000 23.12482 ? 29  ARG B CG  1 
ATOM   1376 C CD  . ARG B 1 29  ? -20.37556 27.53852 -16.91667 1.000 31.27729 ? 29  ARG B CD  1 
ATOM   1377 N NE  . ARG B 1 29  ? -21.75467 27.09722 -17.11622 1.000 36.64087 ? 29  ARG B NE  1 
ATOM   1378 C CZ  . ARG B 1 29  ? -22.13926 25.83418 -17.27894 1.000 40.66328 ? 29  ARG B CZ  1 
ATOM   1379 N NH1 . ARG B 1 29  ? -21.27297 24.83262 -17.26314 1.000 38.95734 ? 29  ARG B NH1 1 
ATOM   1380 N NH2 . ARG B 1 29  ? -23.43228 25.56473 -17.43501 1.000 43.99392 ? 29  ARG B NH2 1 
ATOM   1381 N N   . GLY B 1 30  ? -17.82830 30.33872 -19.37000 1.000 15.04330 ? 30  GLY B N   1 
ATOM   1382 C CA  . GLY B 1 30  ? -18.55321 31.44148 -19.97451 1.000 16.63041 ? 30  GLY B CA  1 
ATOM   1383 C C   . GLY B 1 30  ? -18.26764 31.59644 -21.45504 1.000 18.66355 ? 30  GLY B C   1 
ATOM   1384 O O   . GLY B 1 30  ? -19.17621 31.86845 -22.24576 1.000 19.34187 ? 30  GLY B O   1 
ATOM   1385 N N   . LEU B 1 31  ? -17.00841 31.42374 -21.85898 1.000 15.49545 ? 31  LEU B N   1 
ATOM   1386 C CA  . LEU B 1 31  ? -16.68143 31.63447 -23.26301 1.000 13.24037 ? 31  LEU B CA  1 
ATOM   1387 C C   . LEU B 1 31  ? -16.74197 30.37821 -24.11827 1.000 14.29424 ? 31  LEU B C   1 
ATOM   1388 O O   . LEU B 1 31  ? -16.88030 30.49768 -25.34166 1.000 16.84517 ? 31  LEU B O   1 
ATOM   1389 C CB  . LEU B 1 31  ? -15.29593 32.28427 -23.42919 1.000 13.71705 ? 31  LEU B CB  1 
ATOM   1390 C CG  . LEU B 1 31  ? -15.24139 33.73984 -22.93859 1.000 16.73387 ? 31  LEU B CG  1 
ATOM   1391 C CD1 . LEU B 1 31  ? -13.84538 34.11469 -22.47212 1.000 15.32387 ? 31  LEU B CD1 1 
ATOM   1392 C CD2 . LEU B 1 31  ? -15.76573 34.70061 -24.01834 1.000 20.76075 ? 31  LEU B CD2 1 
ATOM   1393 N N   . THR B 1 32  ? -16.64825 29.18171 -23.53226 1.000 14.37084 ? 32  THR B N   1 
ATOM   1394 C CA  . THR B 1 32  ? -16.62025 27.97830 -24.35143 1.000 13.32015 ? 32  THR B CA  1 
ATOM   1395 C C   . THR B 1 32  ? -17.85419 27.11330 -24.22618 1.000 15.94120 ? 32  THR B C   1 
ATOM   1396 O O   . THR B 1 32  ? -18.04773 26.23854 -25.07391 1.000 17.82660 ? 32  THR B O   1 
ATOM   1397 C CB  . THR B 1 32  ? -15.41058 27.09313 -24.01947 1.000 13.39586 ? 32  THR B CB  1 
ATOM   1398 O OG1 . THR B 1 32  ? -15.58948 26.48506 -22.72431 1.000 13.89700 ? 32  THR B OG1 1 
ATOM   1399 C CG2 . THR B 1 32  ? -14.12451 27.90316 -24.05893 1.000 15.30455 ? 32  THR B CG2 1 
ATOM   1400 N N   . GLY B 1 33  ? -18.66919 27.30781 -23.18810 1.000 14.63055 ? 33  GLY B N   1 
ATOM   1401 C CA  . GLY B 1 33  ? -19.79980 26.43553 -22.94972 1.000 19.60402 ? 33  GLY B CA  1 
ATOM   1402 C C   . GLY B 1 33  ? -19.47041 25.11890 -22.28038 1.000 19.42342 ? 33  GLY B C   1 
ATOM   1403 O O   . GLY B 1 33  ? -20.39387 24.42545 -21.83257 1.000 19.81540 ? 33  GLY B O   1 
ATOM   1404 N N   . THR B 1 34  ? -18.19449 24.73815 -22.21310 1.000 20.10355 ? 34  THR B N   1 
ATOM   1405 C CA  . THR B 1 34  ? -17.80640 23.51403 -21.52443 1.000 17.12864 ? 34  THR B CA  1 
ATOM   1406 C C   . THR B 1 34  ? -18.29385 23.55872 -20.07779 1.000 22.19768 ? 34  THR B C   1 
ATOM   1407 O O   . THR B 1 34  ? -18.24824 24.60667 -19.42798 1.000 21.38918 ? 34  THR B O   1 
ATOM   1408 C CB  . THR B 1 34  ? -16.27620 23.35248 -21.58701 1.000 19.79892 ? 34  THR B CB  1 
ATOM   1409 O OG1 . THR B 1 34  ? -15.85223 23.28876 -22.95523 1.000 26.33091 ? 34  THR B OG1 1 
ATOM   1410 C CG2 . THR B 1 34  ? -15.80909 22.08047 -20.86473 1.000 21.47917 ? 34  THR B CG2 1 
ATOM   1411 N N   . GLN B 1 35  ? -18.77519 22.42008 -19.57033 1.000 19.74433 ? 35  GLN B N   1 
ATOM   1412 C CA  . GLN B 1 35  ? -19.34912 22.40445 -18.22779 1.000 20.72347 ? 35  GLN B CA  1 
ATOM   1413 C C   . GLN B 1 35  ? -18.30919 22.75815 -17.17594 1.000 16.92640 ? 35  GLN B C   1 
ATOM   1414 O O   . GLN B 1 35  ? -17.10062 22.54265 -17.36279 1.000 19.28076 ? 35  GLN B O   1 
ATOM   1415 C CB  . GLN B 1 35  ? -19.94795 21.04091 -17.88769 1.000 18.11937 ? 35  GLN B CB  1 
ATOM   1416 C CG  . GLN B 1 35  ? -20.99930 20.57710 -18.84947 1.000 21.14315 ? 35  GLN B CG  1 
ATOM   1417 C CD  . GLN B 1 35  ? -20.45019 19.63705 -19.87623 1.000 20.64224 ? 35  GLN B CD  1 
ATOM   1418 O OE1 . GLN B 1 35  ? -19.35803 19.84532 -20.40240 1.000 23.23704 ? 35  GLN B OE1 1 
ATOM   1419 N NE2 . GLN B 1 35  ? -21.21801 18.59852 -20.19697 1.000 20.18604 ? 35  GLN B NE2 1 
ATOM   1420 N N   . HIS B 1 36  ? -18.80782 23.30143 -16.05488 1.000 19.03235 ? 36  HIS B N   1 
ATOM   1421 C CA  . HIS B 1 36  ? -17.95367 23.70521 -14.93927 1.000 19.65408 ? 36  HIS B CA  1 
ATOM   1422 C C   . HIS B 1 36  ? -16.97800 22.59647 -14.57869 1.000 17.01180 ? 36  HIS B C   1 
ATOM   1423 O O   . HIS B 1 36  ? -15.77656 22.82364 -14.40662 1.000 15.17456 ? 36  HIS B O   1 
ATOM   1424 C CB  . HIS B 1 36  ? -18.78767 23.98276 -13.68544 1.000 24.83133 ? 36  HIS B CB  1 
ATOM   1425 C CG  . HIS B 1 36  ? -19.33075 25.37017 -13.57029 1.000 33.10666 ? 36  HIS B CG  1 
ATOM   1426 N ND1 . HIS B 1 36  ? -20.53795 25.73513 -14.12711 1.000 37.37669 ? 36  HIS B ND1 1 
ATOM   1427 C CD2 . HIS B 1 36  ? -18.84296 26.47939 -12.96520 1.000 35.44337 ? 36  HIS B CD2 1 
ATOM   1428 C CE1 . HIS B 1 36  ? -20.78554 27.00088 -13.84130 1.000 30.92163 ? 36  HIS B CE1 1 
ATOM   1429 N NE2 . HIS B 1 36  ? -19.76215 27.48218 -13.15880 1.000 37.13317 ? 36  HIS B NE2 1 
ATOM   1430 N N   . PHE B 1 37  ? -17.50081 21.38390 -14.41851 1.000 16.21524 ? 37  PHE B N   1 
ATOM   1431 C CA  . PHE B 1 37  ? -16.72972 20.31537 -13.80518 1.000 11.74588 ? 37  PHE B CA  1 
ATOM   1432 C C   . PHE B 1 37  ? -15.59964 19.81277 -14.68572 1.000 13.85841 ? 37  PHE B C   1 
ATOM   1433 O O   . PHE B 1 37  ? -14.77375 19.03715 -14.20313 1.000 14.76289 ? 37  PHE B O   1 
ATOM   1434 C CB  . PHE B 1 37  ? -17.63209 19.13542 -13.42373 1.000 15.19145 ? 37  PHE B CB  1 
ATOM   1435 C CG  . PHE B 1 37  ? -18.59385 18.70804 -14.50711 1.000 15.65955 ? 37  PHE B CG  1 
ATOM   1436 C CD1 . PHE B 1 37  ? -18.16012 17.95218 -15.58364 1.000 15.47216 ? 37  PHE B CD1 1 
ATOM   1437 C CD2 . PHE B 1 37  ? -19.94501 19.01806 -14.41080 1.000 16.92050 ? 37  PHE B CD2 1 
ATOM   1438 C CE1 . PHE B 1 37  ? -19.04887 17.54001 -16.56680 1.000 20.16210 ? 37  PHE B CE1 1 
ATOM   1439 C CE2 . PHE B 1 37  ? -20.83955 18.60573 -15.38925 1.000 17.09173 ? 37  PHE B CE2 1 
ATOM   1440 C CZ  . PHE B 1 37  ? -20.39188 17.87633 -16.46469 1.000 19.05893 ? 37  PHE B CZ  1 
ATOM   1441 N N   . LEU B 1 38  ? -15.53931 20.20674 -15.95709 1.000 12.41976 ? 38  LEU B N   1 
ATOM   1442 C CA  . LEU B 1 38  ? -14.41369 19.77272 -16.77211 1.000 15.35543 ? 38  LEU B CA  1 
ATOM   1443 C C   . LEU B 1 38  ? -13.21626 20.69886 -16.64801 1.000 13.85953 ? 38  LEU B C   1 
ATOM   1444 O O   . LEU B 1 38  ? -12.16588 20.41588 -17.24339 1.000 15.21411 ? 38  LEU B O   1 
ATOM   1445 C CB  . LEU B 1 38  ? -14.82007 19.66461 -18.24458 1.000 15.62586 ? 38  LEU B CB  1 
ATOM   1446 C CG  . LEU B 1 38  ? -15.73752 18.50417 -18.61361 1.000 17.11036 ? 38  LEU B CG  1 
ATOM   1447 C CD1 . LEU B 1 38  ? -16.01741 18.51101 -20.11974 1.000 19.53782 ? 38  LEU B CD1 1 
ATOM   1448 C CD2 . LEU B 1 38  ? -15.14785 17.16663 -18.18356 1.000 16.27450 ? 38  LEU B CD2 1 
ATOM   1449 N N   . ALA B 1 39  ? -13.34997 21.81034 -15.93120 1.000 12.24581 ? 39  ALA B N   1 
ATOM   1450 C CA  . ALA B 1 39  ? -12.24675 22.75419 -15.78513 1.000 11.90583 ? 39  ALA B CA  1 
ATOM   1451 C C   . ALA B 1 39  ? -11.44316 22.35406 -14.56255 1.000 11.75946 ? 39  ALA B C   1 
ATOM   1452 O O   . ALA B 1 39  ? -11.92468 22.47320 -13.43449 1.000 11.28419 ? 39  ALA B O   1 
ATOM   1453 C CB  . ALA B 1 39  ? -12.75309 24.18964 -15.66061 1.000 11.54646 ? 39  ALA B CB  1 
ATOM   1454 N N   . GLN B 1 40  ? -10.22827 21.86156 -14.78599 1.000 8.24821  ? 40  GLN B N   1 
ATOM   1455 C CA  . GLN B 1 40  ? -9.28761  21.58344 -13.71488 1.000 9.83371  ? 40  GLN B CA  1 
ATOM   1456 C C   . GLN B 1 40  ? -8.31139  22.74847 -13.59150 1.000 11.12117 ? 40  GLN B C   1 
ATOM   1457 O O   . GLN B 1 40  ? -7.73736  23.19606 -14.58756 1.000 11.16691 ? 40  GLN B O   1 
ATOM   1458 C CB  . GLN B 1 40  ? -8.51954  20.28479 -13.97209 1.000 10.72821 ? 40  GLN B CB  1 
ATOM   1459 C CG  . GLN B 1 40  ? -7.45580  20.03132 -12.90840 1.000 9.26559  ? 40  GLN B CG  1 
ATOM   1460 C CD  . GLN B 1 40  ? -6.74912  18.68576 -13.01379 1.000 10.75003 ? 40  GLN B CD  1 
ATOM   1461 O OE1 . GLN B 1 40  ? -5.65874  18.52820 -12.47382 1.000 14.24536 ? 40  GLN B OE1 1 
ATOM   1462 N NE2 . GLN B 1 40  ? -7.36920  17.70589 -13.67977 1.000 9.86029  ? 40  GLN B NE2 1 
ATOM   1463 N N   . VAL B 1 41  ? -8.15837  23.25740 -12.37990 1.000 8.03451  ? 41  VAL B N   1 
ATOM   1464 C CA  . VAL B 1 41  ? -7.14378  24.24792 -12.05510 1.000 9.48911  ? 41  VAL B CA  1 
ATOM   1465 C C   . VAL B 1 41  ? -6.19886  23.57608 -11.07456 1.000 8.83993  ? 41  VAL B C   1 
ATOM   1466 O O   . VAL B 1 41  ? -6.61410  23.12383 -10.00436 1.000 10.35920 ? 41  VAL B O   1 
ATOM   1467 C CB  . VAL B 1 41  ? -7.76338  25.52780 -11.47659 1.000 7.87726  ? 41  VAL B CB  1 
ATOM   1468 C CG1 . VAL B 1 41  ? -6.67218  26.44961 -10.97881 1.000 12.10685 ? 41  VAL B CG1 1 
ATOM   1469 C CG2 . VAL B 1 41  ? -8.59887  26.20730 -12.55430 1.000 8.18675  ? 41  VAL B CG2 1 
ATOM   1470 N N   . ASN B 1 42  ? -4.93965  23.47373 -11.45733 1.000 7.95175  ? 42  ASN B N   1 
ATOM   1471 C CA  . ASN B 1 42  ? -3.95536  22.67641 -10.74415 1.000 9.29117  ? 42  ASN B CA  1 
ATOM   1472 C C   . ASN B 1 42  ? -2.82310  23.60155 -10.31167 1.000 8.42486  ? 42  ASN B C   1 
ATOM   1473 O O   . ASN B 1 42  ? -1.97168  23.96224 -11.12680 1.000 10.62456 ? 42  ASN B O   1 
ATOM   1474 C CB  . ASN B 1 42  ? -3.47729  21.54618 -11.64510 1.000 8.24068  ? 42  ASN B CB  1 
ATOM   1475 C CG  . ASN B 1 42  ? -2.76541  20.45909 -10.87525 1.000 11.05951 ? 42  ASN B CG  1 
ATOM   1476 O OD1 . ASN B 1 42  ? -1.90983  20.74434 -10.04282 1.000 15.36448 ? 42  ASN B OD1 1 
ATOM   1477 N ND2 . ASN B 1 42  ? -3.12887  19.20971 -11.13416 1.000 11.07561 ? 42  ASN B ND2 1 
ATOM   1478 N N   . PHE B 1 43  ? -2.82049  24.00666 -9.03736  1.000 10.79628 ? 43  PHE B N   1 
ATOM   1479 C CA  . PHE B 1 43  ? -1.83818  24.97110 -8.54799  1.000 10.20769 ? 43  PHE B CA  1 
ATOM   1480 C C   . PHE B 1 43  ? -0.50615  24.28931 -8.26317  1.000 10.79423 ? 43  PHE B C   1 
ATOM   1481 O O   . PHE B 1 43  ? -0.44978  23.27377 -7.56089  1.000 10.78447 ? 43  PHE B O   1 
ATOM   1482 C CB  . PHE B 1 43  ? -2.33211  25.66520 -7.27399  1.000 10.66218 ? 43  PHE B CB  1 
ATOM   1483 C CG  . PHE B 1 43  ? -3.39852  26.69698 -7.50941  1.000 9.33594  ? 43  PHE B CG  1 
ATOM   1484 C CD1 . PHE B 1 43  ? -3.06471  27.96673 -7.94369  1.000 10.26168 ? 43  PHE B CD1 1 
ATOM   1485 C CD2 . PHE B 1 43  ? -4.73504  26.39822 -7.28398  1.000 10.97637 ? 43  PHE B CD2 1 
ATOM   1486 C CE1 . PHE B 1 43  ? -4.03148  28.92348 -8.14565  1.000 10.98135 ? 43  PHE B CE1 1 
ATOM   1487 C CE2 . PHE B 1 43  ? -5.72436  27.35468 -7.50241  1.000 9.41177  ? 43  PHE B CE2 1 
ATOM   1488 C CZ  . PHE B 1 43  ? -5.36233  28.61687 -7.93836  1.000 9.67172  ? 43  PHE B CZ  1 
ATOM   1489 N N   . GLN B 1 44  ? 0.56815   24.86902 -8.79248  1.000 7.87747  ? 44  GLN B N   1 
ATOM   1490 C CA  . GLN B 1 44  ? 1.92971   24.37346 -8.61731  1.000 9.14386  ? 44  GLN B CA  1 
ATOM   1491 C C   . GLN B 1 44  ? 2.70305   25.44816 -7.87495  1.000 10.98776 ? 44  GLN B C   1 
ATOM   1492 O O   . GLN B 1 44  ? 3.06641   26.46865 -8.46706  1.000 9.21370  ? 44  GLN B O   1 
ATOM   1493 C CB  . GLN B 1 44  ? 2.57040   24.06601 -9.96678  1.000 9.55975  ? 44  GLN B CB  1 
ATOM   1494 C CG  . GLN B 1 44  ? 1.82236   22.96545 -10.72639 1.000 9.83278  ? 44  GLN B CG  1 
ATOM   1495 C CD  . GLN B 1 44  ? 2.04070   21.59434 -10.08473 1.000 13.65041 ? 44  GLN B CD  1 
ATOM   1496 O OE1 . GLN B 1 44  ? 3.17000   21.20372 -9.81729  1.000 19.06149 ? 44  GLN B OE1 1 
ATOM   1497 N NE2 . GLN B 1 44  ? 0.95657   20.87573 -9.81976  1.000 8.08328  ? 44  GLN B NE2 1 
ATOM   1498 N N   . GLU B 1 45  ? 2.95249   25.21967 -6.58439  1.000 9.23043  ? 45  GLU B N   1 
ATOM   1499 C CA  . GLU B 1 45  ? 3.63669   26.19493 -5.74808  1.000 10.19214 ? 45  GLU B CA  1 
ATOM   1500 C C   . GLU B 1 45  ? 5.11184   25.85688 -5.66352  1.000 10.90430 ? 45  GLU B C   1 
ATOM   1501 O O   . GLU B 1 45  ? 5.48058   24.68581 -5.53737  1.000 11.55690 ? 45  GLU B O   1 
ATOM   1502 C CB  . GLU B 1 45  ? 3.03708   26.22823 -4.34758  1.000 12.35759 ? 45  GLU B CB  1 
ATOM   1503 C CG  . GLU B 1 45  ? 1.63909   26.82217 -4.29865  1.000 11.27856 ? 45  GLU B CG  1 
ATOM   1504 C CD  . GLU B 1 45  ? 1.00387   26.64758 -2.94818  1.000 15.89131 ? 45  GLU B CD  1 
ATOM   1505 O OE1 . GLU B 1 45  ? 0.82409   25.48850 -2.54099  1.000 16.53284 ? 45  GLU B OE1 1 
ATOM   1506 O OE2 . GLU B 1 45  ? 0.69751   27.66837 -2.29588  1.000 22.40779 ? 45  GLU B OE2 1 
ATOM   1507 N N   . GLN B 1 46  ? 5.94663   26.88338 -5.74310  1.000 11.02861 ? 46  GLN B N   1 
ATOM   1508 C CA  . GLN B 1 46  ? 7.38390   26.76309 -5.57592  1.000 11.12421 ? 46  GLN B CA  1 
ATOM   1509 C C   . GLN B 1 46  ? 7.84466   27.90145 -4.68731  1.000 10.15487 ? 46  GLN B C   1 
ATOM   1510 O O   . GLN B 1 46  ? 7.18144   28.93996 -4.60944  1.000 9.79964  ? 46  GLN B O   1 
ATOM   1511 C CB  . GLN B 1 46  ? 8.12527   26.82435 -6.91747  1.000 12.36211 ? 46  GLN B CB  1 
ATOM   1512 C CG  . GLN B 1 46  ? 7.92637   25.59843 -7.77133  1.000 10.86954 ? 46  GLN B CG  1 
ATOM   1513 C CD  . GLN B 1 46  ? 8.70704   24.41412 -7.24852  1.000 11.36861 ? 46  GLN B CD  1 
ATOM   1514 O OE1 . GLN B 1 46  ? 9.87033   24.54911 -6.82913  1.000 13.80643 ? 46  GLN B OE1 1 
ATOM   1515 N NE2 . GLN B 1 46  ? 8.07353   23.24559 -7.25220  1.000 15.78348 ? 46  GLN B NE2 1 
ATOM   1516 N N   . PRO B 1 47  ? 8.98147   27.75162 -4.02225  1.000 13.31421 ? 47  PRO B N   1 
ATOM   1517 C CA  . PRO B 1 47  ? 9.48348   28.86122 -3.20073  1.000 11.61092 ? 47  PRO B CA  1 
ATOM   1518 C C   . PRO B 1 47  ? 9.73086   30.11528 -4.02196  1.000 12.39935 ? 47  PRO B C   1 
ATOM   1519 O O   . PRO B 1 47  ? 10.17200  30.05571 -5.17357  1.000 12.91976 ? 47  PRO B O   1 
ATOM   1520 C CB  . PRO B 1 47  ? 10.79382  28.30745 -2.61736  1.000 14.11140 ? 47  PRO B CB  1 
ATOM   1521 C CG  . PRO B 1 47  ? 11.14508  27.15622 -3.46756  1.000 16.95457 ? 47  PRO B CG  1 
ATOM   1522 C CD  . PRO B 1 47  ? 9.82674   26.55388 -3.89167  1.000 12.43830 ? 47  PRO B CD  1 
ATOM   1523 N N   . ALA B 1 48  ? 9.43569   31.26907 -3.41978  1.000 14.41446 ? 48  ALA B N   1 
ATOM   1524 C CA  . ALA B 1 48  ? 9.81448   32.52718 -4.04387  1.000 12.29039 ? 48  ALA B CA  1 
ATOM   1525 C C   . ALA B 1 48  ? 11.31465  32.52951 -4.30596  1.000 14.94168 ? 48  ALA B C   1 
ATOM   1526 O O   . ALA B 1 48  ? 12.09963  31.97987 -3.52459  1.000 15.11563 ? 48  ALA B O   1 
ATOM   1527 C CB  . ALA B 1 48  ? 9.42424   33.71896 -3.15561  1.000 15.29626 ? 48  ALA B CB  1 
ATOM   1528 N N   . GLY B 1 49  ? 11.70638  33.11194 -5.43484  1.000 13.69612 ? 49  GLY B N   1 
ATOM   1529 C CA  . GLY B 1 49  ? 13.07890  33.08247 -5.88187  1.000 14.78573 ? 49  GLY B CA  1 
ATOM   1530 C C   . GLY B 1 49  ? 13.37090  32.02127 -6.92426  1.000 11.87767 ? 49  GLY B C   1 
ATOM   1531 O O   . GLY B 1 49  ? 14.48580  31.99865 -7.47690  1.000 12.88590 ? 49  GLY B O   1 
ATOM   1532 N N   . ASN B 1 50  ? 12.40247  31.14403 -7.21578  1.000 9.81772  ? 50  ASN B N   1 
ATOM   1533 C CA  . ASN B 1 50  ? 12.57639  30.14798 -8.26212  1.000 9.17855  ? 50  ASN B CA  1 
ATOM   1534 C C   . ASN B 1 50  ? 12.19684  30.68031 -9.63931  1.000 10.09254 ? 50  ASN B C   1 
ATOM   1535 O O   . ASN B 1 50  ? 12.44241  29.98942 -10.63477 1.000 10.98489 ? 50  ASN B O   1 
ATOM   1536 C CB  . ASN B 1 50  ? 11.76439  28.87902 -7.94167  1.000 12.62317 ? 50  ASN B CB  1 
ATOM   1537 C CG  . ASN B 1 50  ? 12.54462  27.88691 -7.07792  1.000 12.91391 ? 50  ASN B CG  1 
ATOM   1538 O OD1 . ASN B 1 50  ? 13.55922  28.24371 -6.48555  1.000 16.62891 ? 50  ASN B OD1 1 
ATOM   1539 N ND2 . ASN B 1 50  ? 12.06162  26.64352 -6.99073  1.000 13.80014 ? 50  ASN B ND2 1 
ATOM   1540 N N   . VAL B 1 51  ? 11.66862  31.90569 -9.74271  1.000 10.42742 ? 51  VAL B N   1 
ATOM   1541 C CA  . VAL B 1 51  ? 11.37576  32.50714 -11.04657 1.000 11.47060 ? 51  VAL B CA  1 
ATOM   1542 C C   . VAL B 1 51  ? 12.44281  33.53804 -11.37358 1.000 11.11072 ? 51  VAL B C   1 
ATOM   1543 O O   . VAL B 1 51  ? 12.78974  34.37357 -10.52292 1.000 11.20983 ? 51  VAL B O   1 
ATOM   1544 C CB  . VAL B 1 51  ? 9.98053   33.15715 -11.07971 1.000 11.94424 ? 51  VAL B CB  1 
ATOM   1545 C CG1 . VAL B 1 51  ? 9.75561   33.86060 -12.41717 1.000 11.40487 ? 51  VAL B CG1 1 
ATOM   1546 C CG2 . VAL B 1 51  ? 8.90609   32.11696 -10.85270 1.000 11.60700 ? 51  VAL B CG2 1 
ATOM   1547 N N   . PHE B 1 52  ? 12.94775  33.49613 -12.61015 1.000 11.20893 ? 52  PHE B N   1 
ATOM   1548 C CA  . PHE B 1 52  ? 13.86389  34.49154 -13.14263 1.000 10.82630 ? 52  PHE B CA  1 
ATOM   1549 C C   . PHE B 1 52  ? 13.26505  35.09218 -14.40294 1.000 11.02825 ? 52  PHE B C   1 
ATOM   1550 O O   . PHE B 1 52  ? 12.73494  34.37042 -15.25611 1.000 11.15320 ? 52  PHE B O   1 
ATOM   1551 C CB  . PHE B 1 52  ? 15.24048  33.87232 -13.46675 1.000 11.09618 ? 52  PHE B CB  1 
ATOM   1552 C CG  . PHE B 1 52  ? 15.98552  33.42747 -12.25681 1.000 12.71997 ? 52  PHE B CG  1 
ATOM   1553 C CD1 . PHE B 1 52  ? 15.58408  32.29454 -11.57267 1.000 10.47273 ? 52  PHE B CD1 1 
ATOM   1554 C CD2 . PHE B 1 52  ? 17.07939  34.14145 -11.79379 1.000 13.52957 ? 52  PHE B CD2 1 
ATOM   1555 C CE1 . PHE B 1 52  ? 16.24611  31.86484 -10.44846 1.000 11.89660 ? 52  PHE B CE1 1 
ATOM   1556 C CE2 . PHE B 1 52  ? 17.74133  33.73101 -10.65399 1.000 13.53937 ? 52  PHE B CE2 1 
ATOM   1557 C CZ  . PHE B 1 52  ? 17.33633  32.58907 -9.97991  1.000 14.50016 ? 52  PHE B CZ  1 
ATOM   1558 N N   . LEU B 1 53  ? 13.34545  36.41514 -14.51656 1.000 11.37821 ? 53  LEU B N   1 
ATOM   1559 C CA  . LEU B 1 53  ? 12.93554  37.13370 -15.71608 1.000 9.98155  ? 53  LEU B CA  1 
ATOM   1560 C C   . LEU B 1 53  ? 14.15525  37.89505 -16.21117 1.000 12.04056 ? 53  LEU B C   1 
ATOM   1561 O O   . LEU B 1 53  ? 14.71629  38.71221 -15.46857 1.000 14.68284 ? 53  LEU B O   1 
ATOM   1562 C CB  . LEU B 1 53  ? 11.77241  38.08927 -15.42980 1.000 12.65713 ? 53  LEU B CB  1 
ATOM   1563 C CG  . LEU B 1 53  ? 10.49100  37.43770 -14.91874 1.000 12.65201 ? 53  LEU B CG  1 
ATOM   1564 C CD1 . LEU B 1 53  ? 9.42378   38.50495 -14.64386 1.000 12.10319 ? 53  LEU B CD1 1 
ATOM   1565 C CD2 . LEU B 1 53  ? 9.95359   36.45249 -15.92702 1.000 12.30724 ? 53  LEU B CD2 1 
ATOM   1566 N N   . GLY B 1 54  ? 14.58244  37.60480 -17.44041 1.000 12.53228 ? 54  GLY B N   1 
ATOM   1567 C CA  . GLY B 1 54  ? 15.79621  38.20647 -17.96513 1.000 13.74266 ? 54  GLY B CA  1 
ATOM   1568 C C   . GLY B 1 54  ? 17.02550  37.95251 -17.12209 1.000 15.98276 ? 54  GLY B C   1 
ATOM   1569 O O   . GLY B 1 54  ? 17.94018  38.78657 -17.10001 1.000 16.60652 ? 54  GLY B O   1 
ATOM   1570 N N   . GLY B 1 55  ? 17.07604  36.82131 -16.41913 1.000 13.77084 ? 55  GLY B N   1 
ATOM   1571 C CA  . GLY B 1 55  ? 18.19041  36.51854 -15.54774 1.000 13.87078 ? 55  GLY B CA  1 
ATOM   1572 C C   . GLY B 1 55  ? 18.07922  37.08276 -14.14811 1.000 15.41730 ? 55  GLY B C   1 
ATOM   1573 O O   . GLY B 1 55  ? 18.94202  36.78456 -13.31205 1.000 16.64230 ? 55  GLY B O   1 
ATOM   1574 N N   . VAL B 1 56  ? 17.04915  37.88175 -13.86467 1.000 14.61234 ? 56  VAL B N   1 
ATOM   1575 C CA  . VAL B 1 56  ? 16.88551  38.56196 -12.58260 1.000 15.22937 ? 56  VAL B CA  1 
ATOM   1576 C C   . VAL B 1 56  ? 15.95515  37.73131 -11.71295 1.000 16.31172 ? 56  VAL B C   1 
ATOM   1577 O O   . VAL B 1 56  ? 14.83225  37.42230 -12.11883 1.000 16.30422 ? 56  VAL B O   1 
ATOM   1578 C CB  . VAL B 1 56  ? 16.33107  39.98391 -12.77093 1.000 15.19895 ? 56  VAL B CB  1 
ATOM   1579 C CG1 . VAL B 1 56  ? 16.07400  40.64290 -11.41157 1.000 18.10681 ? 56  VAL B CG1 1 
ATOM   1580 C CG2 . VAL B 1 56  ? 17.27844  40.81561 -13.61909 1.000 16.96573 ? 56  VAL B CG2 1 
ATOM   1581 N N   . GLN B 1 57  ? 16.42177  37.35435 -10.52658 1.000 16.15205 ? 57  GLN B N   1 
ATOM   1582 C CA  . GLN B 1 57  ? 15.58800  36.59699 -9.60079  1.000 13.42741 ? 57  GLN B CA  1 
ATOM   1583 C C   . GLN B 1 57  ? 14.40286  37.44046 -9.15096  1.000 19.12136 ? 57  GLN B C   1 
ATOM   1584 O O   . GLN B 1 57  ? 14.56353  38.61018 -8.79447  1.000 17.63004 ? 57  GLN B O   1 
ATOM   1585 C CB  . GLN B 1 57  ? 16.42239  36.14381 -8.40409  1.000 13.14770 ? 57  GLN B CB  1 
ATOM   1586 C CG  . GLN B 1 57  ? 15.65456  35.29911 -7.42501  1.000 13.43877 ? 57  GLN B CG  1 
ATOM   1587 C CD  . GLN B 1 57  ? 16.51186  34.86541 -6.27319  1.000 18.46859 ? 57  GLN B CD  1 
ATOM   1588 O OE1 . GLN B 1 57  ? 16.87066  35.66941 -5.42408  1.000 29.87496 ? 57  GLN B OE1 1 
ATOM   1589 N NE2 . GLN B 1 57  ? 16.81877  33.57604 -6.21819  1.000 30.32404 ? 57  GLN B NE2 1 
ATOM   1590 N N   . GLN B 1 58  ? 13.20712  36.85464 -9.19287  1.000 12.71736 ? 58  GLN B N   1 
ATOM   1591 C CA  . GLN B 1 58  ? 11.97974  37.54863 -8.83634  1.000 12.60283 ? 58  GLN B CA  1 
ATOM   1592 C C   . GLN B 1 58  ? 11.53730  37.22940 -7.41464  1.000 14.27836 ? 58  GLN B C   1 
ATOM   1593 O O   . GLN B 1 58  ? 11.94914  36.23792 -6.80714  1.000 14.98570 ? 58  GLN B O   1 
ATOM   1594 C CB  . GLN B 1 58  ? 10.85405  37.16697 -9.80100  1.000 12.80693 ? 58  GLN B CB  1 
ATOM   1595 C CG  . GLN B 1 58  ? 11.16110  37.48642 -11.25538 1.000 14.12537 ? 58  GLN B CG  1 
ATOM   1596 C CD  . GLN B 1 58  ? 11.36173  38.96483 -11.49742 1.000 16.92980 ? 58  GLN B CD  1 
ATOM   1597 O OE1 . GLN B 1 58  ? 10.44624  39.77361 -11.30203 1.000 18.06674 ? 58  GLN B OE1 1 
ATOM   1598 N NE2 . GLN B 1 58  ? 12.53485  39.32265 -11.98044 1.000 15.20306 ? 58  GLN B NE2 1 
ATOM   1599 N N   . GLY B 1 59  ? 10.67691  38.10393 -6.88794  1.000 16.76570 ? 59  GLY B N   1 
ATOM   1600 C CA  . GLY B 1 59  ? 9.92114   37.81616 -5.68496  1.000 13.55572 ? 59  GLY B CA  1 
ATOM   1601 C C   . GLY B 1 59  ? 8.77784   36.86494 -5.98361  1.000 18.13145 ? 59  GLY B C   1 
ATOM   1602 O O   . GLY B 1 59  ? 8.85703   36.00734 -6.87211  1.000 19.95274 ? 59  GLY B O   1 
ATOM   1603 N N   . GLY B 1 60  ? 7.69124   37.01467 -5.24166  1.000 19.39033 ? 60  GLY B N   1 
ATOM   1604 C CA  . GLY B 1 60  ? 6.67245   35.99108 -5.30177  1.000 17.91132 ? 60  GLY B CA  1 
ATOM   1605 C C   . GLY B 1 60  ? 5.44987   36.33199 -6.12203  1.000 14.25153 ? 60  GLY B C   1 
ATOM   1606 O O   . GLY B 1 60  ? 4.41171   35.68249 -5.96594  1.000 14.68187 ? 60  GLY B O   1 
ATOM   1607 N N   . ASP B 1 61  ? 5.53950   37.33132 -6.99977  1.000 14.52699 ? 61  ASP B N   1 
ATOM   1608 C CA  . ASP B 1 61  ? 4.31729   37.81485 -7.62922  1.000 15.23962 ? 61  ASP B CA  1 
ATOM   1609 C C   . ASP B 1 61  ? 4.02219   37.21141 -8.99693  1.000 13.23483 ? 61  ASP B C   1 
ATOM   1610 O O   . ASP B 1 61  ? 2.86551   37.25690 -9.42260  1.000 16.05952 ? 61  ASP B O   1 
ATOM   1611 C CB  . ASP B 1 61  ? 4.33904   39.33848 -7.76170  1.000 18.01278 ? 61  ASP B CB  1 
ATOM   1612 C CG  . ASP B 1 61  ? 4.10861   40.03986 -6.43417  1.000 20.41773 ? 61  ASP B CG  1 
ATOM   1613 O OD1 . ASP B 1 61  ? 3.31680   39.52548 -5.61805  1.000 23.66444 ? 61  ASP B OD1 1 
ATOM   1614 O OD2 . ASP B 1 61  ? 4.71570   41.10489 -6.21598  1.000 27.57501 ? 61  ASP B OD2 1 
ATOM   1615 N N   . THR B 1 62  ? 4.99514   36.65687 -9.70873  1.000 12.12004 ? 62  THR B N   1 
ATOM   1616 C CA  . THR B 1 62  ? 4.68560   36.14231 -11.03886 1.000 12.42306 ? 62  THR B CA  1 
ATOM   1617 C C   . THR B 1 62  ? 3.64787   35.02108 -10.97027 1.000 10.05133 ? 62  THR B C   1 
ATOM   1618 O O   . THR B 1 62  ? 3.68612   34.16646 -10.07973 1.000 13.40263 ? 62  THR B O   1 
ATOM   1619 C CB  . THR B 1 62  ? 5.95124   35.62457 -11.72492 1.000 14.16558 ? 62  THR B CB  1 
ATOM   1620 O OG1 . THR B 1 62  ? 6.98649   36.60763 -11.64146 1.000 16.81370 ? 62  THR B OG1 1 
ATOM   1621 C CG2 . THR B 1 62  ? 5.68431   35.34667 -13.21446 1.000 14.55505 ? 62  THR B CG2 1 
ATOM   1622 N N   . ILE B 1 63  ? 2.70664   35.03347 -11.91723 1.000 7.86484  ? 63  ILE B N   1 
ATOM   1623 C CA  . ILE B 1 63  ? 1.74432   33.95545 -12.09594 1.000 7.19408  ? 63  ILE B CA  1 
ATOM   1624 C C   . ILE B 1 63  ? 1.83206   33.50784 -13.54426 1.000 11.57434 ? 63  ILE B C   1 
ATOM   1625 O O   . ILE B 1 63  ? 1.65121   34.32634 -14.44914 1.000 11.96092 ? 63  ILE B O   1 
ATOM   1626 C CB  . ILE B 1 63  ? 0.30469   34.40015 -11.77082 1.000 9.62542  ? 63  ILE B CB  1 
ATOM   1627 C CG1 . ILE B 1 63  ? 0.20082   34.88375 -10.32166 1.000 11.32002 ? 63  ILE B CG1 1 
ATOM   1628 C CG2 . ILE B 1 63  ? -0.64983  33.23830 -11.98623 1.000 9.89503  ? 63  ILE B CG2 1 
ATOM   1629 C CD1 . ILE B 1 63  ? -1.20122  35.41715 -9.94703  1.000 13.15345 ? 63  ILE B CD1 1 
ATOM   1630 N N   . PHE B 1 64  ? 2.10715   32.22303 -13.76975 1.000 8.66184  ? 64  PHE B N   1 
ATOM   1631 C CA  . PHE B 1 64  ? 2.08169   31.64519 -15.11266 1.000 8.08341  ? 64  PHE B CA  1 
ATOM   1632 C C   . PHE B 1 64  ? 0.95116   30.62826 -15.19970 1.000 7.73419  ? 64  PHE B C   1 
ATOM   1633 O O   . PHE B 1 64  ? 0.92192   29.65739 -14.44697 1.000 7.23035  ? 64  PHE B O   1 
ATOM   1634 C CB  . PHE B 1 64  ? 3.42313   30.98316 -15.47253 1.000 7.95577  ? 64  PHE B CB  1 
ATOM   1635 C CG  . PHE B 1 64  ? 3.40168   30.23413 -16.79431 1.000 8.77590  ? 64  PHE B CG  1 
ATOM   1636 C CD1 . PHE B 1 64  ? 2.80976   30.79826 -17.92499 1.000 10.07852 ? 64  PHE B CD1 1 
ATOM   1637 C CD2 . PHE B 1 64  ? 3.99859   28.97498 -16.91558 1.000 8.76398  ? 64  PHE B CD2 1 
ATOM   1638 C CE1 . PHE B 1 64  ? 2.79680   30.09581 -19.16405 1.000 10.85752 ? 64  PHE B CE1 1 
ATOM   1639 C CE2 . PHE B 1 64  ? 3.98694   28.28555 -18.12277 1.000 9.72028  ? 64  PHE B CE2 1 
ATOM   1640 C CZ  . PHE B 1 64  ? 3.39095   28.84192 -19.24859 1.000 9.17854  ? 64  PHE B CZ  1 
ATOM   1641 N N   . VAL B 1 65  ? 0.03001   30.85606 -16.12836 1.000 7.50292  ? 65  VAL B N   1 
ATOM   1642 C CA  . VAL B 1 65  ? -1.07543  29.95349 -16.40501 1.000 7.97887  ? 65  VAL B CA  1 
ATOM   1643 C C   . VAL B 1 65  ? -0.78183  29.24962 -17.71706 1.000 7.81608  ? 65  VAL B C   1 
ATOM   1644 O O   . VAL B 1 65  ? -0.68267  29.89567 -18.76710 1.000 8.61515  ? 65  VAL B O   1 
ATOM   1645 C CB  . VAL B 1 65  ? -2.41895  30.69677 -16.46624 1.000 8.31534  ? 65  VAL B CB  1 
ATOM   1646 C CG1 . VAL B 1 65  ? -3.54885  29.71100 -16.76715 1.000 9.04283  ? 65  VAL B CG1 1 
ATOM   1647 C CG2 . VAL B 1 65  ? -2.67711  31.44799 -15.15254 1.000 11.38081 ? 65  VAL B CG2 1 
ATOM   1648 N N   . HIS B 1 66  ? -0.61487  27.92908 -17.65066 1.000 6.85992  ? 66  HIS B N   1 
ATOM   1649 C CA  . HIS B 1 66  ? -0.44726  27.07697 -18.82602 1.000 6.61552  ? 66  HIS B CA  1 
ATOM   1650 C C   . HIS B 1 66  ? -1.75526  26.31145 -19.02067 1.000 7.25956  ? 66  HIS B C   1 
ATOM   1651 O O   . HIS B 1 66  ? -2.05738  25.37855 -18.27295 1.000 7.66224  ? 66  HIS B O   1 
ATOM   1652 C CB  . HIS B 1 66  ? 0.73512   26.14480 -18.64931 1.000 6.44168  ? 66  HIS B CB  1 
ATOM   1653 C CG  . HIS B 1 66  ? 1.14613   25.43789 -19.90520 1.000 8.02734  ? 66  HIS B CG  1 
ATOM   1654 N ND1 . HIS B 1 66  ? 2.03758   24.38284 -19.90286 1.000 9.29803  ? 66  HIS B ND1 1 
ATOM   1655 C CD2 . HIS B 1 66  ? 0.80823   25.64628 -21.19917 1.000 9.06266  ? 66  HIS B CD2 1 
ATOM   1656 C CE1 . HIS B 1 66  ? 2.21355   23.95966 -21.14375 1.000 11.20337 ? 66  HIS B CE1 1 
ATOM   1657 N NE2 . HIS B 1 66  ? 1.48537   24.71043 -21.95260 1.000 9.56166  ? 66  HIS B NE2 1 
ATOM   1658 N N   . GLY B 1 67  ? -2.54749  26.73893 -20.00201 1.000 6.84291  ? 67  GLY B N   1 
ATOM   1659 C CA  . GLY B 1 67  ? -3.82420  26.10748 -20.27493 1.000 6.81665  ? 67  GLY B CA  1 
ATOM   1660 C C   . GLY B 1 67  ? -3.68918  25.04650 -21.34609 1.000 7.80109  ? 67  GLY B C   1 
ATOM   1661 O O   . GLY B 1 67  ? -3.08603  25.28313 -22.39644 1.000 8.61748  ? 67  GLY B O   1 
ATOM   1662 N N   . LEU B 1 68  ? -4.23031  23.87456 -21.06567 1.000 7.72555  ? 68  LEU B N   1 
ATOM   1663 C CA  . LEU B 1 68  ? -4.15624  22.72434 -21.96582 1.000 7.01312  ? 68  LEU B CA  1 
ATOM   1664 C C   . LEU B 1 68  ? -5.56736  22.43430 -22.46475 1.000 8.10779  ? 68  LEU B C   1 
ATOM   1665 O O   . LEU B 1 68  ? -6.43395  22.00995 -21.69109 1.000 8.74123  ? 68  LEU B O   1 
ATOM   1666 C CB  . LEU B 1 68  ? -3.54114  21.51963 -21.24606 1.000 6.83389  ? 68  LEU B CB  1 
ATOM   1667 C CG  . LEU B 1 68  ? -2.15553  21.80567 -20.64598 1.000 8.01277  ? 68  LEU B CG  1 
ATOM   1668 C CD1 . LEU B 1 68  ? -1.62088  20.61131 -19.84689 1.000 10.36418 ? 68  LEU B CD1 1 
ATOM   1669 C CD2 . LEU B 1 68  ? -1.15957  22.19820 -21.75118 1.000 10.61964 ? 68  LEU B CD2 1 
ATOM   1670 N N   . HIS B 1 69  ? -5.77457  22.64607 -23.76494 1.000 8.31791  ? 69  HIS B N   1 
ATOM   1671 C CA  . HIS B 1 69  ? -7.07377  22.69795 -24.42045 1.000 7.57054  ? 69  HIS B CA  1 
ATOM   1672 C C   . HIS B 1 69  ? -7.18365  21.63618 -25.50294 1.000 9.01681  ? 69  HIS B C   1 
ATOM   1673 O O   . HIS B 1 69  ? -6.17611  21.13873 -26.02227 1.000 8.51110  ? 69  HIS B O   1 
ATOM   1674 C CB  . HIS B 1 69  ? -7.30325  24.05766 -25.11032 1.000 8.03948  ? 69  HIS B CB  1 
ATOM   1675 C CG  . HIS B 1 69  ? -7.45682  25.21113 -24.17632 1.000 14.00447 ? 69  HIS B CG  1 
ATOM   1676 N ND1 . HIS B 1 69  ? -7.52780  26.51137 -24.62616 1.000 15.89415 ? 69  HIS B ND1 1 
ATOM   1677 C CD2 . HIS B 1 69  ? -7.59191  25.26841 -22.83050 1.000 11.68655 ? 69  HIS B CD2 1 
ATOM   1678 C CE1 . HIS B 1 69  ? -7.66834  27.32470 -23.59401 1.000 13.53056 ? 69  HIS B CE1 1 
ATOM   1679 N NE2 . HIS B 1 69  ? -7.70856  26.59614 -22.49258 1.000 11.84139 ? 69  HIS B NE2 1 
ATOM   1680 N N   . ARG B 1 70  ? -8.42355  21.35577 -25.90408 1.000 8.91585  ? 70  ARG B N   1 
ATOM   1681 C CA  . ARG B 1 70  ? -8.66190  20.64104 -27.15272 1.000 11.61663 ? 70  ARG B CA  1 
ATOM   1682 C C   . ARG B 1 70  ? -8.46071  21.56954 -28.34606 1.000 10.58390 ? 70  ARG B C   1 
ATOM   1683 O O   . ARG B 1 70  ? -8.79149  22.75527 -28.28250 1.000 10.91710 ? 70  ARG B O   1 
ATOM   1684 C CB  . ARG B 1 70  ? -10.09197 20.09452 -27.20856 1.000 9.07033  ? 70  ARG B CB  1 
ATOM   1685 C CG  . ARG B 1 70  ? -10.36941 18.91916 -26.28842 1.000 9.12711  ? 70  ARG B CG  1 
ATOM   1686 C CD  . ARG B 1 70  ? -11.86786 18.70359 -26.19391 1.000 13.40900 ? 70  ARG B CD  1 
ATOM   1687 N NE  . ARG B 1 70  ? -12.47176 19.69394 -25.30340 1.000 16.71566 ? 70  ARG B NE  1 
ATOM   1688 C CZ  . ARG B 1 70  ? -13.77522 19.88151 -25.15913 1.000 18.87419 ? 70  ARG B CZ  1 
ATOM   1689 N NH1 . ARG B 1 70  ? -14.65490 19.15047 -25.82242 1.000 18.91253 ? 70  ARG B NH1 1 
ATOM   1690 N NH2 . ARG B 1 70  ? -14.20772 20.82264 -24.31918 1.000 21.13844 ? 70  ARG B NH2 1 
ATOM   1691 N N   . GLU B 1 71  ? -7.93121  21.00991 -29.44322 1.000 9.63250  ? 71  GLU B N   1 
ATOM   1692 C CA  . GLU B 1 71  ? -7.97704  21.69659 -30.73516 1.000 9.17602  ? 71  GLU B CA  1 
ATOM   1693 C C   . GLU B 1 71  ? -9.41714  21.96345 -31.14641 1.000 8.52575  ? 71  GLU B C   1 
ATOM   1694 O O   . GLU B 1 71  ? -10.33283 21.20718 -30.80682 1.000 11.43970 ? 71  GLU B O   1 
ATOM   1695 C CB  . GLU B 1 71  ? -7.32669  20.84696 -31.82603 1.000 11.55986 ? 71  GLU B CB  1 
ATOM   1696 C CG  . GLU B 1 71  ? -5.83330  20.74933 -31.72838 1.000 13.81540 ? 71  GLU B CG  1 
ATOM   1697 C CD  . GLU B 1 71  ? -5.24387  19.71245 -32.66178 1.000 17.17364 ? 71  GLU B CD  1 
ATOM   1698 O OE1 . GLU B 1 71  ? -5.99945  19.00868 -33.37393 1.000 17.34135 ? 71  GLU B OE1 1 
ATOM   1699 O OE2 . GLU B 1 71  ? -4.00781  19.59111 -32.65868 1.000 18.46321 ? 71  GLU B OE2 1 
ATOM   1700 N N   . GLY B 1 72  ? -9.62090  23.04164 -31.91051 1.000 10.60168 ? 72  GLY B N   1 
ATOM   1701 C CA  . GLY B 1 72  ? -10.92140 23.25415 -32.53566 1.000 9.60811  ? 72  GLY B CA  1 
ATOM   1702 C C   . GLY B 1 72  ? -11.53286 24.62749 -32.35697 1.000 8.88450  ? 72  GLY B C   1 
ATOM   1703 O O   . GLY B 1 72  ? -12.54617 24.94294 -33.00246 1.000 11.07110 ? 72  GLY B O   1 
ATOM   1704 N N   . ARG B 1 73  ? -10.96321 25.44941 -31.47311 1.000 9.69309  ? 73  ARG B N   1 
ATOM   1705 C CA  . ARG B 1 73  ? -11.52203 26.77113 -31.24353 1.000 8.35771  ? 73  ARG B CA  1 
ATOM   1706 C C   . ARG B 1 73  ? -10.80374 27.82667 -32.06819 1.000 9.49351  ? 73  ARG B C   1 
ATOM   1707 O O   . ARG B 1 73  ? -9.66065  27.65278 -32.50045 1.000 9.49796  ? 73  ARG B O   1 
ATOM   1708 C CB  . ARG B 1 73  ? -11.47869 27.12904 -29.76268 1.000 12.26919 ? 73  ARG B CB  1 
ATOM   1709 C CG  . ARG B 1 73  ? -12.43613 26.25314 -28.98953 1.000 13.92765 ? 73  ARG B CG  1 
ATOM   1710 C CD  . ARG B 1 73  ? -12.59513 26.68059 -27.56122 1.000 16.08005 ? 73  ARG B CD  1 
ATOM   1711 N NE  . ARG B 1 73  ? -13.27591 25.62139 -26.82863 1.000 17.09197 ? 73  ARG B NE  1 
ATOM   1712 C CZ  . ARG B 1 73  ? -12.67702 24.83915 -25.94236 1.000 20.64633 ? 73  ARG B CZ  1 
ATOM   1713 N NH1 . ARG B 1 73  ? -11.38098 24.95803 -25.68081 1.000 17.24024 ? 73  ARG B NH1 1 
ATOM   1714 N NH2 . ARG B 1 73  ? -13.38792 23.89619 -25.32393 1.000 21.88137 ? 73  ARG B NH2 1 
ATOM   1715 N N   . SER B 1 74  ? -11.50409 28.93516 -32.28729 1.000 9.87171  ? 74  SER B N   1 
ATOM   1716 C CA  . SER B 1 74  ? -10.96251 29.98437 -33.13159 1.000 8.81679  ? 74  SER B CA  1 
ATOM   1717 C C   . SER B 1 74  ? -9.89578  30.78354 -32.39708 1.000 9.96741  ? 74  SER B C   1 
ATOM   1718 O O   . SER B 1 74  ? -9.83301  30.81626 -31.16729 1.000 9.89216  ? 74  SER B O   1 
ATOM   1719 C CB  . SER B 1 74  ? -12.07006 30.92300 -33.59612 1.000 11.11239 ? 74  SER B CB  1 
ATOM   1720 O OG  . SER B 1 74  ? -12.56231 31.68606 -32.51061 1.000 10.75387 ? 74  SER B OG  1 
ATOM   1721 N N   . ALA B 1 75  ? -9.02564  31.41245 -33.17833 1.000 9.48758  ? 75  ALA B N   1 
ATOM   1722 C CA  . ALA B 1 75  ? -8.04510  32.31966 -32.59413 1.000 10.40480 ? 75  ALA B CA  1 
ATOM   1723 C C   . ALA B 1 75  ? -8.73385  33.47528 -31.88082 1.000 10.57455 ? 75  ALA B C   1 
ATOM   1724 O O   . ALA B 1 75  ? -8.26836  33.93826 -30.83631 1.000 10.25695 ? 75  ALA B O   1 
ATOM   1725 C CB  . ALA B 1 75  ? -7.11874  32.84862 -33.68454 1.000 11.24474 ? 75  ALA B CB  1 
ATOM   1726 N N   . ASP B 1 76  ? -9.85056  33.94650 -32.42853 1.000 10.70574 ? 76  ASP B N   1 
ATOM   1727 C CA  . ASP B 1 76  ? -10.60756 35.00971 -31.77561 1.000 11.75697 ? 76  ASP B CA  1 
ATOM   1728 C C   . ASP B 1 76  ? -11.04365 34.57682 -30.38361 1.000 11.47813 ? 76  ASP B C   1 
ATOM   1729 O O   . ASP B 1 76  ? -10.82470 35.29118 -29.39748 1.000 11.56314 ? 76  ASP B O   1 
ATOM   1730 C CB  . ASP B 1 76  ? -11.81668 35.35262 -32.64667 1.000 13.12133 ? 76  ASP B CB  1 
ATOM   1731 C CG  . ASP B 1 76  ? -12.63307 36.53055 -32.13307 1.000 22.44475 ? 76  ASP B CG  1 
ATOM   1732 O OD1 . ASP B 1 76  ? -12.37056 37.06706 -31.03697 1.000 28.74415 ? 76  ASP B OD1 1 
ATOM   1733 O OD2 . ASP B 1 76  ? -13.57195 36.91950 -32.85740 1.000 37.33159 ? 76  ASP B OD2 1 
ATOM   1734 N N   . LEU B 1 77  ? -11.66834 33.40211 -30.28611 1.000 9.68747  ? 77  LEU B N   1 
ATOM   1735 C CA  . LEU B 1 77  ? -12.16117 32.93667 -28.99746 1.000 7.96680  ? 77  LEU B CA  1 
ATOM   1736 C C   . LEU B 1 77  ? -11.01532 32.71273 -28.01404 1.000 9.63170  ? 77  LEU B C   1 
ATOM   1737 O O   . LEU B 1 77  ? -11.10791 33.09797 -26.83888 1.000 11.41007 ? 77  LEU B O   1 
ATOM   1738 C CB  . LEU B 1 77  ? -12.97451 31.65509 -29.20468 1.000 10.78055 ? 77  LEU B CB  1 
ATOM   1739 C CG  . LEU B 1 77  ? -13.79027 31.11415 -28.02891 1.000 15.34180 ? 77  LEU B CG  1 
ATOM   1740 C CD1 . LEU B 1 77  ? -12.89186 30.28584 -27.08604 1.000 18.00506 ? 77  LEU B CD1 1 
ATOM   1741 C CD2 . LEU B 1 77  ? -14.50231 32.25952 -27.31912 1.000 17.19771 ? 77  LEU B CD2 1 
ATOM   1742 N N   . LYS B 1 78  ? -9.92819  32.08196 -28.46622 1.000 9.48649  ? 78  LYS B N   1 
ATOM   1743 C CA  . LYS B 1 78  ? -8.81379  31.84383 -27.55908 1.000 9.27523  ? 78  LYS B CA  1 
ATOM   1744 C C   . LYS B 1 78  ? -8.23533  33.15599 -27.04948 1.000 10.97109 ? 78  LYS B C   1 
ATOM   1745 O O   . LYS B 1 78  ? -7.83252  33.24837 -25.88531 1.000 11.96436 ? 78  LYS B O   1 
ATOM   1746 C CB  . LYS B 1 78  ? -7.73394  31.00452 -28.24223 1.000 10.11170 ? 78  LYS B CB  1 
ATOM   1747 C CG  . LYS B 1 78  ? -8.19869  29.57295 -28.49396 1.000 11.86052 ? 78  LYS B CG  1 
ATOM   1748 C CD  . LYS B 1 78  ? -7.13514  28.74590 -29.18459 1.000 9.89763  ? 78  LYS B CD  1 
ATOM   1749 C CE  . LYS B 1 78  ? -7.07162  29.04904 -30.68091 1.000 11.25012 ? 78  LYS B CE  1 
ATOM   1750 N NZ  . LYS B 1 78  ? -6.07860  28.20310 -31.40076 1.000 11.71135 ? 78  LYS B NZ  1 
ATOM   1751 N N   . GLY B 1 79  ? -8.20218  34.18291 -27.90631 1.000 10.34351 ? 79  GLY B N   1 
ATOM   1752 C CA  . GLY B 1 79  ? -7.71013  35.47736 -27.47171 1.000 10.52861 ? 79  GLY B CA  1 
ATOM   1753 C C   . GLY B 1 79  ? -8.60896  36.10596 -26.42270 1.000 12.48887 ? 79  GLY B C   1 
ATOM   1754 O O   . GLY B 1 79  ? -8.12469  36.62266 -25.41584 1.000 10.52486 ? 79  GLY B O   1 
ATOM   1755 N N   . GLN B 1 80  ? -9.92947  36.04017 -26.62794 1.000 11.19555 ? 80  GLN B N   1 
ATOM   1756 C CA  . GLN B 1 80  ? -10.85571 36.54911 -25.61629 1.000 10.71268 ? 80  GLN B CA  1 
ATOM   1757 C C   . GLN B 1 80  ? -10.68294 35.81406 -24.29765 1.000 10.25025 ? 80  GLN B C   1 
ATOM   1758 O O   . GLN B 1 80  ? -10.72783 36.42789 -23.21987 1.000 9.78292  ? 80  GLN B O   1 
ATOM   1759 C CB  . GLN B 1 80  ? -12.29997 36.40054 -26.09074 1.000 13.50562 ? 80  GLN B CB  1 
ATOM   1760 C CG  . GLN B 1 80  ? -12.68440 37.21669 -27.29055 1.000 14.78353 ? 80  GLN B CG  1 
ATOM   1761 C CD  . GLN B 1 80  ? -14.10146 36.89417 -27.70388 1.000 22.24835 ? 80  GLN B CD  1 
ATOM   1762 O OE1 . GLN B 1 80  ? -14.98343 36.76319 -26.85485 1.000 25.83471 ? 80  GLN B OE1 1 
ATOM   1763 N NE2 . GLN B 1 80  ? -14.32418 36.72338 -29.00302 1.000 29.19789 ? 80  GLN B NE2 1 
ATOM   1764 N N   . LEU B 1 81  ? -10.51146 34.48383 -24.36798 1.000 8.47954  ? 81  LEU B N   1 
ATOM   1765 C CA  . LEU B 1 81  ? -10.37386 33.68219 -23.15538 1.000 7.05418  ? 81  LEU B CA  1 
ATOM   1766 C C   . LEU B 1 81  ? -9.07548  33.99955 -22.43370 1.000 9.26264  ? 81  LEU B C   1 
ATOM   1767 O O   . LEU B 1 81  ? -9.07516  34.15529 -21.21067 1.000 10.79127 ? 81  LEU B O   1 
ATOM   1768 C CB  . LEU B 1 81  ? -10.45948 32.19086 -23.49925 1.000 9.45306  ? 81  LEU B CB  1 
ATOM   1769 C CG  . LEU B 1 81  ? -10.31317 31.12688 -22.38952 1.000 10.50753 ? 81  LEU B CG  1 
ATOM   1770 C CD1 . LEU B 1 81  ? -11.27924 31.35146 -21.23265 1.000 10.31877 ? 81  LEU B CD1 1 
ATOM   1771 C CD2 . LEU B 1 81  ? -10.48800 29.71672 -22.94922 1.000 11.83100 ? 81  LEU B CD2 1 
ATOM   1772 N N   . ALA B 1 82  ? -7.96027  34.11552 -23.16604 1.000 8.24570  ? 82  ALA B N   1 
ATOM   1773 C CA  . ALA B 1 82  ? -6.70098  34.47699 -22.51253 1.000 8.08366  ? 82  ALA B CA  1 
ATOM   1774 C C   . ALA B 1 82  ? -6.79136  35.85165 -21.85075 1.000 9.86857  ? 82  ALA B C   1 
ATOM   1775 O O   . ALA B 1 82  ? -6.34538  36.02351 -20.71452 1.000 8.85243  ? 82  ALA B O   1 
ATOM   1776 C CB  . ALA B 1 82  ? -5.54319  34.42875 -23.51953 1.000 9.78072  ? 82  ALA B CB  1 
ATOM   1777 N N   . GLN B 1 83  ? -7.37687  36.84441 -22.53860 1.000 10.87287 ? 83  GLN B N   1 
ATOM   1778 C CA  . GLN B 1 83  ? -7.52454  38.16007 -21.91587 1.000 10.15161 ? 83  GLN B CA  1 
ATOM   1779 C C   . GLN B 1 83  ? -8.41601  38.09718 -20.68572 1.000 9.69337  ? 83  GLN B C   1 
ATOM   1780 O O   . GLN B 1 83  ? -8.14947  38.76895 -19.67947 1.000 11.16882 ? 83  GLN B O   1 
ATOM   1781 C CB  . GLN B 1 83  ? -8.10348  39.16632 -22.90503 1.000 12.68158 ? 83  GLN B CB  1 
ATOM   1782 C CG  . GLN B 1 83  ? -8.19923  40.58786 -22.33706 1.000 13.04885 ? 83  GLN B CG  1 
ATOM   1783 C CD  . GLN B 1 83  ? -6.83879  41.18608 -22.07859 1.000 16.69988 ? 83  GLN B CD  1 
ATOM   1784 O OE1 . GLN B 1 83  ? -6.01604  41.27373 -22.98637 1.000 16.45858 ? 83  GLN B OE1 1 
ATOM   1785 N NE2 . GLN B 1 83  ? -6.58032  41.58395 -20.83087 1.000 18.33707 ? 83  GLN B NE2 1 
ATOM   1786 N N   . ARG B 1 84  ? -9.50045  37.31825 -20.75277 1.000 9.22562  ? 84  ARG B N   1 
ATOM   1787 C CA  . ARG B 1 84  ? -10.39182 37.23153 -19.59809 1.000 13.14363 ? 84  ARG B CA  1 
ATOM   1788 C C   . ARG B 1 84  ? -9.69487  36.59092 -18.40693 1.000 11.91680 ? 84  ARG B C   1 
ATOM   1789 O O   . ARG B 1 84  ? -9.94493  36.96795 -17.25593 1.000 10.71337 ? 84  ARG B O   1 
ATOM   1790 C CB  . ARG B 1 84  ? -11.65916 36.45154 -19.94336 1.000 13.96871 ? 84  ARG B CB  1 
ATOM   1791 C CG  . ARG B 1 84  ? -12.59663 36.42268 -18.73367 1.000 15.98402 ? 84  ARG B CG  1 
ATOM   1792 C CD  . ARG B 1 84  ? -14.03794 36.10653 -19.01751 1.000 18.03156 ? 84  ARG B CD  1 
ATOM   1793 N NE  . ARG B 1 84  ? -14.68031 35.77734 -17.75055 1.000 21.77303 ? 84  ARG B NE  1 
ATOM   1794 C CZ  . ARG B 1 84  ? -15.89934 35.27145 -17.61630 1.000 21.41798 ? 84  ARG B CZ  1 
ATOM   1795 N NH1 . ARG B 1 84  ? -16.71173 35.13509 -18.65662 1.000 24.90162 ? 84  ARG B NH1 1 
ATOM   1796 N NH2 . ARG B 1 84  ? -16.30824 34.88279 -16.40940 1.000 19.99130 ? 84  ARG B NH2 1 
ATOM   1797 N N   . ILE B 1 85  ? -8.82381  35.61169 -18.65690 1.000 10.01508 ? 85  ILE B N   1 
ATOM   1798 C CA  . ILE B 1 85  ? -8.06254  35.01342 -17.56421 1.000 11.58961 ? 85  ILE B CA  1 
ATOM   1799 C C   . ILE B 1 85  ? -7.13238  36.04706 -16.94601 1.000 9.15593  ? 85  ILE B C   1 
ATOM   1800 O O   . ILE B 1 85  ? -7.06727  36.19106 -15.72188 1.000 10.54482 ? 85  ILE B O   1 
ATOM   1801 C CB  . ILE B 1 85  ? -7.30585  33.77049 -18.05435 1.000 8.16012  ? 85  ILE B CB  1 
ATOM   1802 C CG1 . ILE B 1 85  ? -8.32023  32.62367 -18.23314 1.000 9.15482  ? 85  ILE B CG1 1 
ATOM   1803 C CG2 . ILE B 1 85  ? -6.20169  33.39032 -17.08424 1.000 11.17996 ? 85  ILE B CG2 1 
ATOM   1804 C CD1 . ILE B 1 85  ? -7.80483  31.44957 -19.04831 1.000 11.35455 ? 85  ILE B CD1 1 
ATOM   1805 N N   . VAL B 1 86  ? -6.42202  36.80863 -17.78289 1.000 9.77855  ? 86  VAL B N   1 
ATOM   1806 C CA  . VAL B 1 86  ? -5.56025  37.86918 -17.25935 1.000 9.48752  ? 86  VAL B CA  1 
ATOM   1807 C C   . VAL B 1 86  ? -6.36406  38.83274 -16.38939 1.000 12.16450 ? 86  VAL B C   1 
ATOM   1808 O O   . VAL B 1 86  ? -5.99476  39.11120 -15.24315 1.000 12.01317 ? 86  VAL B O   1 
ATOM   1809 C CB  . VAL B 1 86  ? -4.85330  38.62104 -18.39915 1.000 11.33832 ? 86  VAL B CB  1 
ATOM   1810 C CG1 . VAL B 1 86  ? -4.15566  39.86670 -17.84361 1.000 12.63783 ? 86  VAL B CG1 1 
ATOM   1811 C CG2 . VAL B 1 86  ? -3.84713  37.70883 -19.11514 1.000 10.09346 ? 86  VAL B CG2 1 
ATOM   1812 N N   . ASP B 1 87  ? -7.46262  39.36836 -16.93240 1.000 10.96576 ? 87  ASP B N   1 
ATOM   1813 C CA  . ASP B 1 87  ? -8.27507  40.33548 -16.19236 1.000 11.15308 ? 87  ASP B CA  1 
ATOM   1814 C C   . ASP B 1 87  ? -8.83222  39.73646 -14.90730 1.000 15.27845 ? 87  ASP B C   1 
ATOM   1815 O O   . ASP B 1 87  ? -8.76457  40.35773 -13.83680 1.000 13.93139 ? 87  ASP B O   1 
ATOM   1816 C CB  . ASP B 1 87  ? -9.43296  40.83481 -17.05786 1.000 12.08986 ? 87  ASP B CB  1 
ATOM   1817 C CG  . ASP B 1 87  ? -8.97167  41.66739 -18.24221 1.000 18.08650 ? 87  ASP B CG  1 
ATOM   1818 O OD1 . ASP B 1 87  ? -7.85799  42.21490 -18.18610 1.000 22.49646 ? 87  ASP B OD1 1 
ATOM   1819 O OD2 . ASP B 1 87  ? -9.74450  41.79584 -19.21730 1.000 16.67093 ? 87  ASP B OD2 1 
ATOM   1820 N N   . ASP B 1 88  ? -9.41737  38.53868 -14.99775 1.000 13.08255 ? 88  ASP B N   1 
ATOM   1821 C CA  . ASP B 1 88  ? -10.13870 37.99694 -13.84946 1.000 10.85426 ? 88  ASP B CA  1 
ATOM   1822 C C   . ASP B 1 88  ? -9.21658  37.40538 -12.79412 1.000 11.55507 ? 88  ASP B C   1 
ATOM   1823 O O   . ASP B 1 88  ? -9.56425  37.40977 -11.61113 1.000 12.97827 ? 88  ASP B O   1 
ATOM   1824 C CB  . ASP B 1 88  ? -11.16102 36.95244 -14.29793 1.000 13.08640 ? 88  ASP B CB  1 
ATOM   1825 C CG  . ASP B 1 88  ? -12.29556 37.55690 -15.09549 1.000 14.00143 ? 88  ASP B CG  1 
ATOM   1826 O OD1 . ASP B 1 88  ? -12.31870 38.79553 -15.25786 1.000 18.15842 ? 88  ASP B OD1 1 
ATOM   1827 O OD2 . ASP B 1 88  ? -13.17496 36.79698 -15.52594 1.000 15.26731 ? 88  ASP B OD2 1 
ATOM   1828 N N   . VAL B 1 89  ? -8.05019  36.88825 -13.18699 1.000 10.83357 ? 89  VAL B N   1 
ATOM   1829 C CA  . VAL B 1 89  ? -7.08004  36.45892 -12.18768 1.000 11.03959 ? 89  VAL B CA  1 
ATOM   1830 C C   . VAL B 1 89  ? -6.44560  37.66878 -11.51511 1.000 14.52858 ? 89  VAL B C   1 
ATOM   1831 O O   . VAL B 1 89  ? -6.12336  37.62966 -10.32072 1.000 12.90448 ? 89  VAL B O   1 
ATOM   1832 C CB  . VAL B 1 89  ? -6.02931  35.54815 -12.83688 1.000 9.67626  ? 89  VAL B CB  1 
ATOM   1833 C CG1 . VAL B 1 89  ? -4.87124  35.30901 -11.89146 1.000 11.36411 ? 89  VAL B CG1 1 
ATOM   1834 C CG2 . VAL B 1 89  ? -6.66834  34.22201 -13.20430 1.000 13.56372 ? 89  VAL B CG2 1 
ATOM   1835 N N   . SER B 1 90  ? -6.27561  38.76657 -12.25532 1.000 11.91532 ? 90  SER B N   1 
ATOM   1836 C CA  . SER B 1 90  ? -5.77629  39.99261 -11.64673 1.000 12.99489 ? 90  SER B CA  1 
ATOM   1837 C C   . SER B 1 90  ? -6.69063  40.45415 -10.52121 1.000 14.18759 ? 90  SER B C   1 
ATOM   1838 O O   . SER B 1 90  ? -6.21560  40.87446 -9.45949  1.000 17.21623 ? 90  SER B O   1 
ATOM   1839 C CB  . SER B 1 90  ? -5.64437  41.08452 -12.70947 1.000 15.64246 ? 90  SER B CB  1 
ATOM   1840 O OG  . SER B 1 90  ? -5.24647  42.31112 -12.12101 1.000 21.04461 ? 90  SER B OG  1 
ATOM   1841 N N   . VAL B 1 91  ? -8.00268  40.37013 -10.72534 1.000 13.87435 ? 91  VAL B N   1 
ATOM   1842 C CA  . VAL B 1 91  ? -8.93432  40.74224 -9.66116  1.000 15.05891 ? 91  VAL B CA  1 
ATOM   1843 C C   . VAL B 1 91  ? -8.87947  39.72570 -8.52216  1.000 16.61460 ? 91  VAL B C   1 
ATOM   1844 O O   . VAL B 1 91  ? -8.74458  40.09237 -7.34724  1.000 16.52117 ? 91  VAL B O   1 
ATOM   1845 C CB  . VAL B 1 91  ? -10.35486 40.89087 -10.23854 1.000 16.30871 ? 91  VAL B CB  1 
ATOM   1846 C CG1 . VAL B 1 91  ? -11.38449 41.06217 -9.13016  1.000 19.89425 ? 91  VAL B CG1 1 
ATOM   1847 C CG2 . VAL B 1 91  ? -10.40975 42.05608 -11.22352 1.000 19.07609 ? 91  VAL B CG2 1 
ATOM   1848 N N   . ALA B 1 92  ? -8.96038  38.43042 -8.84883  1.000 13.52004 ? 92  ALA B N   1 
ATOM   1849 C CA  . ALA B 1 92  ? -9.09336  37.41270 -7.80404  1.000 12.72448 ? 92  ALA B CA  1 
ATOM   1850 C C   . ALA B 1 92  ? -7.84288  37.32336 -6.93744  1.000 15.71607 ? 92  ALA B C   1 
ATOM   1851 O O   . ALA B 1 92  ? -7.94018  37.12565 -5.71924  1.000 16.21943 ? 92  ALA B O   1 
ATOM   1852 C CB  . ALA B 1 92  ? -9.40594  36.04699 -8.41904  1.000 14.11510 ? 92  ALA B CB  1 
ATOM   1853 N N   . ALA B 1 93  ? -6.66513  37.45544 -7.54567  1.000 13.24321 ? 93  ALA B N   1 
ATOM   1854 C CA  . ALA B 1 93  ? -5.40102  37.37013 -6.83499  1.000 17.14812 ? 93  ALA B CA  1 
ATOM   1855 C C   . ALA B 1 93  ? -4.90527  38.71517 -6.32291  1.000 16.16917 ? 93  ALA B C   1 
ATOM   1856 O O   . ALA B 1 93  ? -3.86890  38.74730 -5.65348  1.000 19.70349 ? 93  ALA B O   1 
ATOM   1857 C CB  . ALA B 1 93  ? -4.32809  36.74698 -7.73651  1.000 14.98190 ? 93  ALA B CB  1 
ATOM   1858 N N   . GLU B 1 94  ? -5.60314  39.80838 -6.62242  1.000 17.18740 ? 94  GLU B N   1 
ATOM   1859 C CA  . GLU B 1 94  ? -5.18720  41.15687 -6.22782  1.000 20.26733 ? 94  GLU B CA  1 
ATOM   1860 C C   . GLU B 1 94  ? -3.75413  41.42595 -6.68215  1.000 20.15812 ? 94  GLU B C   1 
ATOM   1861 O O   . GLU B 1 94  ? -2.86144  41.78018 -5.90451  1.000 17.45572 ? 94  GLU B O   1 
ATOM   1862 C CB  . GLU B 1 94  ? -5.35351  41.36612 -4.71865  1.000 22.15219 ? 94  GLU B CB  1 
ATOM   1863 C CG  . GLU B 1 94  ? -6.80799  41.26300 -4.28837  1.000 27.04838 ? 94  GLU B CG  1 
ATOM   1864 C CD  . GLU B 1 94  ? -7.00096  41.37807 -2.79325  1.000 31.54790 ? 94  GLU B CD  1 
ATOM   1865 O OE1 . GLU B 1 94  ? -6.99232  42.51747 -2.28492  1.000 36.29258 ? 94  GLU B OE1 1 
ATOM   1866 O OE2 . GLU B 1 94  ? -7.17143  40.33138 -2.13399  1.000 35.47020 ? 94  GLU B OE2 1 
ATOM   1867 N N   . ILE B 1 95  ? -3.55346  41.24992 -7.98394  1.000 18.93887 ? 95  ILE B N   1 
ATOM   1868 C CA  . ILE B 1 95  ? -2.22880  41.30321 -8.58108  1.000 18.32916 ? 95  ILE B CA  1 
ATOM   1869 C C   . ILE B 1 95  ? -2.29546  42.06762 -9.89438  1.000 19.61832 ? 95  ILE B C   1 
ATOM   1870 O O   . ILE B 1 95  ? -3.24746  41.91707 -10.66847 1.000 19.42995 ? 95  ILE B O   1 
ATOM   1871 C CB  . ILE B 1 95  ? -1.66593  39.88670 -8.77891  1.000 18.65349 ? 95  ILE B CB  1 
ATOM   1872 C CG1 . ILE B 1 95  ? -0.18859  39.96249 -9.11197  1.000 19.78464 ? 95  ILE B CG1 1 
ATOM   1873 C CG2 . ILE B 1 95  ? -2.46742  39.11166 -9.83680  1.000 18.85314 ? 95  ILE B CG2 1 
ATOM   1874 C CD1 . ILE B 1 95  ? 0.42055   38.66267 -9.12085  1.000 20.05251 ? 95  ILE B CD1 1 
ATOM   1875 N N   . ASP B 1 96  ? -1.28485  42.90253 -10.13362 1.000 14.99195 ? 96  ASP B N   1 
ATOM   1876 C CA  . ASP B 1 96  ? -1.22857  43.68239 -11.36098 1.000 16.48377 ? 96  ASP B CA  1 
ATOM   1877 C C   . ASP B 1 96  ? -1.09075  42.74617 -12.55622 1.000 13.93823 ? 96  ASP B C   1 
ATOM   1878 O O   . ASP B 1 96  ? -0.39913  41.72415 -12.49186 1.000 13.62464 ? 96  ASP B O   1 
ATOM   1879 C CB  . ASP B 1 96  ? -0.05183  44.66075 -11.30235 1.000 18.72137 ? 96  ASP B CB  1 
ATOM   1880 C CG  . ASP B 1 96  ? -0.10373  45.74826 -12.38960 1.000 28.65122 ? 96  ASP B CG  1 
ATOM   1881 O OD1 . ASP B 1 96  ? 0.06516   45.45789 -13.60204 1.000 22.83739 ? 96  ASP B OD1 1 
ATOM   1882 O OD2 . ASP B 1 96  ? -0.27942  46.93260 -12.01538 1.000 36.18058 ? 96  ASP B OD2 1 
ATOM   1883 N N   . ARG B 1 97  ? -1.77951  43.08852 -13.64820 1.000 12.12813 ? 97  ARG B N   1 
ATOM   1884 C CA  . ARG B 1 97  ? -1.73819  42.24556 -14.84258 1.000 10.46552 ? 97  ARG B CA  1 
ATOM   1885 C C   . ARG B 1 97  ? -0.33537  42.07519 -15.39715 1.000 12.89961 ? 97  ARG B C   1 
ATOM   1886 O O   . ARG B 1 97  ? -0.09257  41.10149 -16.12006 1.000 10.64390 ? 97  ARG B O   1 
ATOM   1887 C CB  . ARG B 1 97  ? -2.63899  42.81341 -15.93556 1.000 14.18671 ? 97  ARG B CB  1 
ATOM   1888 C CG  . ARG B 1 97  ? -4.06820  43.02206 -15.48186 1.000 15.86597 ? 97  ARG B CG  1 
ATOM   1889 C CD  . ARG B 1 97  ? -4.85284  43.86089 -16.47271 1.000 23.37654 ? 97  ARG B CD  1 
ATOM   1890 N NE  . ARG B 1 97  ? -6.27631  43.62542 -16.30920 1.000 28.76703 ? 97  ARG B NE  1 
ATOM   1891 C CZ  . ARG B 1 97  ? -7.00519  44.19148 -15.35886 1.000 29.17713 ? 97  ARG B CZ  1 
ATOM   1892 N NH1 . ARG B 1 97  ? -6.47623  45.06289 -14.51179 1.000 30.66871 ? 97  ARG B NH1 1 
ATOM   1893 N NH2 . ARG B 1 97  ? -8.28925  43.86157 -15.24108 1.000 29.80528 ? 97  ARG B NH2 1 
ATOM   1894 N N   . LYS B 1 98  ? 0.59320   42.98987 -15.09397 1.000 12.57996 ? 98  LYS B N   1 
ATOM   1895 C CA  . LYS B 1 98  ? 1.95848   42.84543 -15.60741 1.000 10.76223 ? 98  LYS B CA  1 
ATOM   1896 C C   . LYS B 1 98  ? 2.64233   41.59145 -15.09499 1.000 11.70264 ? 98  LYS B C   1 
ATOM   1897 O O   . LYS B 1 98  ? 3.65799   41.17428 -15.66948 1.000 10.62107 ? 98  LYS B O   1 
ATOM   1898 C CB  . LYS B 1 98  ? 2.85170   44.02542 -15.20676 1.000 14.34025 ? 98  LYS B CB  1 
ATOM   1899 C CG  . LYS B 1 98  ? 2.87818   44.26890 -13.69781 1.000 20.79297 ? 98  LYS B CG  1 
ATOM   1900 C CD  . LYS B 1 98  ? 3.60860   45.56386 -13.34770 1.000 22.27907 ? 98  LYS B CD  1 
ATOM   1901 C CE  . LYS B 1 98  ? 3.62794   45.81189 -11.83761 1.000 30.00487 ? 98  LYS B CE  1 
ATOM   1902 N NZ  . LYS B 1 98  ? 3.62175   47.27318 -11.50504 1.000 36.88104 ? 98  LYS B NZ  1 
ATOM   1903 N N   . HIS B 1 99  ? 2.13711   41.00942 -14.01211 1.000 12.65022 ? 99  HIS B N   1 
ATOM   1904 C CA  . HIS B 1 99  ? 2.70188   39.80612 -13.42768 1.000 10.61327 ? 99  HIS B CA  1 
ATOM   1905 C C   . HIS B 1 99  ? 2.14592   38.52394 -14.02750 1.000 10.86221 ? 99  HIS B C   1 
ATOM   1906 O O   . HIS B 1 99  ? 2.58956   37.43942 -13.62452 1.000 10.47438 ? 99  HIS B O   1 
ATOM   1907 C CB  . HIS B 1 99  ? 2.44102   39.76324 -11.92312 1.000 12.86792 ? 99  HIS B CB  1 
ATOM   1908 C CG  . HIS B 1 99  ? 3.16533   40.81857 -11.15187 1.000 13.81183 ? 99  HIS B CG  1 
ATOM   1909 N ND1 . HIS B 1 99  ? 4.53890   40.91007 -11.13605 1.000 16.72376 ? 99  HIS B ND1 1 
ATOM   1910 C CD2 . HIS B 1 99  ? 2.70877   41.80515 -10.34537 1.000 18.57850 ? 99  HIS B CD2 1 
ATOM   1911 C CE1 . HIS B 1 99  ? 4.89901   41.91782 -10.35885 1.000 19.39318 ? 99  HIS B CE1 1 
ATOM   1912 N NE2 . HIS B 1 99  ? 3.80692   42.47304 -9.86233  1.000 21.33367 ? 99  HIS B NE2 1 
ATOM   1913 N N   . ILE B 1 100 ? 1.16717   38.60531 -14.92920 1.000 9.03712  ? 100 ILE B N   1 
ATOM   1914 C CA  . ILE B 1 100 ? 0.39088   37.43801 -15.33756 1.000 7.73676  ? 100 ILE B CA  1 
ATOM   1915 C C   . ILE B 1 100 ? 0.78408   37.02518 -16.74990 1.000 9.19253  ? 100 ILE B C   1 
ATOM   1916 O O   . ILE B 1 100 ? 0.71920   37.82921 -17.69149 1.000 10.62409 ? 100 ILE B O   1 
ATOM   1917 C CB  . ILE B 1 100 ? -1.11906  37.70029 -15.25502 1.000 11.04864 ? 100 ILE B CB  1 
ATOM   1918 C CG1 . ILE B 1 100 ? -1.50055  38.17550 -13.84227 1.000 12.48829 ? 100 ILE B CG1 1 
ATOM   1919 C CG2 . ILE B 1 100 ? -1.87254  36.43471 -15.66912 1.000 10.71439 ? 100 ILE B CG2 1 
ATOM   1920 C CD1 . ILE B 1 100 ? -2.99103  38.51682 -13.69701 1.000 13.40793 ? 100 ILE B CD1 1 
ATOM   1921 N N   . TRP B 1 101 ? 1.17976   35.76116 -16.88909 1.000 9.02818  ? 101 TRP B N   1 
ATOM   1922 C CA  . TRP B 1 101 ? 1.53391   35.14625 -18.15836 1.000 8.14259  ? 101 TRP B CA  1 
ATOM   1923 C C   . TRP B 1 101 ? 0.55675   34.01248 -18.41768 1.000 7.12581  ? 101 TRP B C   1 
ATOM   1924 O O   . TRP B 1 101 ? 0.22337   33.27346 -17.49289 1.000 8.82314  ? 101 TRP B O   1 
ATOM   1925 C CB  . TRP B 1 101 ? 2.95878   34.58576 -18.12643 1.000 8.37490  ? 101 TRP B CB  1 
ATOM   1926 C CG  . TRP B 1 101 ? 4.05079   35.60255 -17.90329 1.000 9.17464  ? 101 TRP B CG  1 
ATOM   1927 C CD1 . TRP B 1 101 ? 4.08763   36.60226 -16.94914 1.000 10.06098 ? 101 TRP B CD1 1 
ATOM   1928 C CD2 . TRP B 1 101 ? 5.29209   35.66676 -18.59215 1.000 9.51621  ? 101 TRP B CD2 1 
ATOM   1929 N NE1 . TRP B 1 101 ? 5.27279   37.29713 -17.03750 1.000 10.40747 ? 101 TRP B NE1 1 
ATOM   1930 C CE2 . TRP B 1 101 ? 6.03401   36.73104 -18.02674 1.000 10.44989 ? 101 TRP B CE2 1 
ATOM   1931 C CE3 . TRP B 1 101 ? 5.85544   34.92324 -19.64160 1.000 8.04323  ? 101 TRP B CE3 1 
ATOM   1932 C CZ2 . TRP B 1 101 ? 7.29146   37.08639 -18.48782 1.000 12.67346 ? 101 TRP B CZ2 1 
ATOM   1933 C CZ3 . TRP B 1 101 ? 7.11159   35.26761 -20.08665 1.000 9.99538  ? 101 TRP B CZ3 1 
ATOM   1934 C CH2 . TRP B 1 101 ? 7.81520   36.34987 -19.51297 1.000 11.82664 ? 101 TRP B CH2 1 
ATOM   1935 N N   . VAL B 1 102 ? 0.10920   33.86841 -19.67185 1.000 7.46342  ? 102 VAL B N   1 
ATOM   1936 C CA  . VAL B 1 102 ? -0.94626  32.90961 -20.02653 1.000 7.28627  ? 102 VAL B CA  1 
ATOM   1937 C C   . VAL B 1 102 ? -0.63696  32.32431 -21.40051 1.000 7.62119  ? 102 VAL B C   1 
ATOM   1938 O O   . VAL B 1 102 ? -0.67496  33.04771 -22.40303 1.000 8.43104  ? 102 VAL B O   1 
ATOM   1939 C CB  . VAL B 1 102 ? -2.34208  33.55370 -20.04444 1.000 6.83639  ? 102 VAL B CB  1 
ATOM   1940 C CG1 . VAL B 1 102 ? -3.40572  32.51451 -20.41911 1.000 8.71282  ? 102 VAL B CG1 1 
ATOM   1941 C CG2 . VAL B 1 102 ? -2.68051  34.21464 -18.69996 1.000 8.59592  ? 102 VAL B CG2 1 
ATOM   1942 N N   . TYR B 1 103 ? -0.36210  31.01996 -21.45489 1.000 7.41962  ? 103 TYR B N   1 
ATOM   1943 C CA  . TYR B 1 103 ? -0.11575  30.29275 -22.70011 1.000 6.93015  ? 103 TYR B CA  1 
ATOM   1944 C C   . TYR B 1 103 ? -1.13583  29.18146 -22.84074 1.000 7.50646  ? 103 TYR B C   1 
ATOM   1945 O O   . TYR B 1 103 ? -1.34466  28.41437 -21.89731 1.000 8.33646  ? 103 TYR B O   1 
ATOM   1946 C CB  . TYR B 1 103 ? 1.26082   29.62983 -22.73285 1.000 7.71888  ? 103 TYR B CB  1 
ATOM   1947 C CG  . TYR B 1 103 ? 2.45151   30.54734 -22.80860 1.000 9.65307  ? 103 TYR B CG  1 
ATOM   1948 C CD1 . TYR B 1 103 ? 2.30790   31.93311 -22.80737 1.000 10.81766 ? 103 TYR B CD1 1 
ATOM   1949 C CD2 . TYR B 1 103 ? 3.73389   30.02319 -22.88152 1.000 9.69210  ? 103 TYR B CD2 1 
ATOM   1950 C CE1 . TYR B 1 103 ? 3.42807   32.77084 -22.87004 1.000 10.03063 ? 103 TYR B CE1 1 
ATOM   1951 C CE2 . TYR B 1 103 ? 4.85690   30.84671 -22.93479 1.000 11.28955 ? 103 TYR B CE2 1 
ATOM   1952 C CZ  . TYR B 1 103 ? 4.70104   32.21663 -22.94169 1.000 11.20423 ? 103 TYR B CZ  1 
ATOM   1953 O OH  . TYR B 1 103 ? 5.81205   33.03729 -23.01575 1.000 11.19864 ? 103 TYR B OH  1 
ATOM   1954 N N   . PHE B 1 104 ? -1.70755  29.05171 -24.03233 1.000 8.22892  ? 104 PHE B N   1 
ATOM   1955 C CA  . PHE B 1 104 ? -2.64766  27.98480 -24.34594 1.000 9.08895  ? 104 PHE B CA  1 
ATOM   1956 C C   . PHE B 1 104 ? -1.99427  26.98271 -25.28819 1.000 8.37688  ? 104 PHE B C   1 
ATOM   1957 O O   . PHE B 1 104 ? -1.50850  27.36361 -26.35542 1.000 8.80909  ? 104 PHE B O   1 
ATOM   1958 C CB  . PHE B 1 104 ? -3.90195  28.53993 -25.02207 1.000 9.77685  ? 104 PHE B CB  1 
ATOM   1959 C CG  . PHE B 1 104 ? -4.80098  29.32835 -24.10951 1.000 13.41920 ? 104 PHE B CG  1 
ATOM   1960 C CD1 . PHE B 1 104 ? -4.60524  29.34153 -22.72440 1.000 11.59293 ? 104 PHE B CD1 1 
ATOM   1961 C CD2 . PHE B 1 104 ? -5.86420  30.04606 -24.64106 1.000 12.05904 ? 104 PHE B CD2 1 
ATOM   1962 C CE1 . PHE B 1 104 ? -5.44873  30.07306 -21.89118 1.000 8.80656  ? 104 PHE B CE1 1 
ATOM   1963 C CE2 . PHE B 1 104 ? -6.71421  30.77392 -23.81343 1.000 13.15332 ? 104 PHE B CE2 1 
ATOM   1964 C CZ  . PHE B 1 104 ? -6.49802  30.79962 -22.44652 1.000 10.70281 ? 104 PHE B CZ  1 
ATOM   1965 N N   . GLY B 1 105 ? -2.00526  25.70995 -24.90683 1.000 7.75321  ? 105 GLY B N   1 
ATOM   1966 C CA  . GLY B 1 105 ? -1.56254  24.62713 -25.77360 1.000 9.38922  ? 105 GLY B CA  1 
ATOM   1967 C C   . GLY B 1 105 ? -2.78128  23.82505 -26.19182 1.000 9.35350  ? 105 GLY B C   1 
ATOM   1968 O O   . GLY B 1 105 ? -3.75489  23.73266 -25.44556 1.000 11.75762 ? 105 GLY B O   1 
ATOM   1969 N N   . GLU B 1 106 ? -2.75031  23.26697 -27.40378 1.000 7.41161  ? 106 GLU B N   1 
ATOM   1970 C CA  . GLU B 1 106 ? -3.89077  22.50483 -27.89659 1.000 7.65182  ? 106 GLU B CA  1 
ATOM   1971 C C   . GLU B 1 106 ? -3.46587  21.13743 -28.40447 1.000 7.49515  ? 106 GLU B C   1 
ATOM   1972 O O   . GLU B 1 106 ? -2.41368  20.99815 -29.03789 1.000 11.14541 ? 106 GLU B O   1 
ATOM   1973 C CB  . GLU B 1 106 ? -4.59207  23.22539 -29.04942 1.000 9.66859  ? 106 GLU B CB  1 
ATOM   1974 C CG  . GLU B 1 106 ? -5.12042  24.60189 -28.75371 1.000 12.20780 ? 106 GLU B CG  1 
ATOM   1975 C CD  . GLU B 1 106 ? -5.24331  25.39331 -30.04466 1.000 11.26625 ? 106 GLU B CD  1 
ATOM   1976 O OE1 . GLU B 1 106 ? -4.20374  25.84191 -30.57156 1.000 12.57744 ? 106 GLU B OE1 1 
ATOM   1977 O OE2 . GLU B 1 106 ? -6.37323  25.51083 -30.56868 1.000 13.32944 ? 106 GLU B OE2 1 
ATOM   1978 N N   . MET B 1 107 ? -4.30869  20.14495 -28.16623 1.000 8.43778  ? 107 MET B N   1 
ATOM   1979 C CA  . MET B 1 107 ? -4.10793  18.79448 -28.66145 1.000 9.33819  ? 107 MET B CA  1 
ATOM   1980 C C   . MET B 1 107 ? -5.40607  18.22273 -29.20495 1.000 7.77631  ? 107 MET B C   1 
ATOM   1981 O O   . MET B 1 107 ? -6.49463  18.67145 -28.83545 1.000 9.02868  ? 107 MET B O   1 
ATOM   1982 C CB  . MET B 1 107 ? -3.53164  17.82576 -27.60882 1.000 10.62201 ? 107 MET B CB  1 
ATOM   1983 C CG  . MET B 1 107 ? -2.28620  18.28845 -26.82421 1.000 11.21316 ? 107 MET B CG  1 
ATOM   1984 S SD  . MET B 1 107 ? -2.30955  17.93721 -25.04870 1.000 12.93098 ? 107 MET B SD  1 
ATOM   1985 C CE  . MET B 1 107 ? -3.15810  19.40699 -24.45537 1.000 13.78071 ? 107 MET B CE  1 
ATOM   1986 N N   . PRO B 1 108 ? -5.32003  17.24123 -30.09817 1.000 9.25747  ? 108 PRO B N   1 
ATOM   1987 C CA  . PRO B 1 108 ? -6.53852  16.55430 -30.55155 1.000 9.94346  ? 108 PRO B CA  1 
ATOM   1988 C C   . PRO B 1 108 ? -7.29842  15.96979 -29.37748 1.000 12.01980 ? 108 PRO B C   1 
ATOM   1989 O O   . PRO B 1 108 ? -6.70605  15.36143 -28.47868 1.000 12.32045 ? 108 PRO B O   1 
ATOM   1990 C CB  . PRO B 1 108 ? -6.01029  15.44814 -31.47407 1.000 13.65967 ? 108 PRO B CB  1 
ATOM   1991 C CG  . PRO B 1 108 ? -4.63019  15.90991 -31.90771 1.000 14.86853 ? 108 PRO B CG  1 
ATOM   1992 C CD  . PRO B 1 108 ? -4.10150  16.79731 -30.80181 1.000 10.69463 ? 108 PRO B CD  1 
ATOM   1993 N N   . ALA B 1 109 ? -8.62439  16.15874 -29.38655 1.000 11.95707 ? 109 ALA B N   1 
ATOM   1994 C CA  . ALA B 1 109 ? -9.43772  15.58493 -28.31219 1.000 10.14745 ? 109 ALA B CA  1 
ATOM   1995 C C   . ALA B 1 109 ? -9.19191  14.08781 -28.17104 1.000 14.34804 ? 109 ALA B C   1 
ATOM   1996 O O   . ALA B 1 109 ? -9.32150  13.52955 -27.07392 1.000 12.42717 ? 109 ALA B O   1 
ATOM   1997 C CB  . ALA B 1 109 ? -10.92207 15.85767 -28.56860 1.000 14.61843 ? 109 ALA B CB  1 
ATOM   1998 N N   . GLN B 1 110 ? -8.82182  13.42880 -29.26901 1.000 14.69222 ? 110 GLN B N   1 
ATOM   1999 C CA  . GLN B 1 110 ? -8.65893  11.99029 -29.29350 1.000 15.26569 ? 110 GLN B CA  1 
ATOM   2000 C C   . GLN B 1 110 ? -7.46565  11.51500 -28.47227 1.000 12.79915 ? 110 GLN B C   1 
ATOM   2001 O O   . GLN B 1 110 ? -7.33786  10.30478 -28.24008 1.000 13.57609 ? 110 GLN B O   1 
ATOM   2002 C CB  . GLN B 1 110 ? -8.55173  11.57577 -30.75727 1.000 19.94726 ? 110 GLN B CB  1 
ATOM   2003 C CG  . GLN B 1 110 ? -9.89453  11.73375 -31.47101 1.000 19.81444 ? 110 GLN B CG  1 
ATOM   2004 C CD  . GLN B 1 110 ? -10.14150 13.13887 -32.04554 1.000 30.34008 ? 110 GLN B CD  1 
ATOM   2005 O OE1 . GLN B 1 110 ? -9.22835  13.97936 -32.16179 1.000 23.51139 ? 110 GLN B OE1 1 
ATOM   2006 N NE2 . GLN B 1 110 ? -11.40278 13.39809 -32.40312 1.000 33.23499 ? 110 GLN B NE2 1 
ATOM   2007 N N   . GLN B 1 111 ? -6.58338  12.42183 -28.02404 1.000 10.72191 ? 111 GLN B N   1 
ATOM   2008 C CA  . GLN B 1 111 ? -5.49078  12.00127 -27.14862 1.000 10.40646 ? 111 GLN B CA  1 
ATOM   2009 C C   . GLN B 1 111 ? -5.57036  12.71178 -25.80101 1.000 10.55899 ? 111 GLN B C   1 
ATOM   2010 O O   . GLN B 1 111 ? -4.54281  12.98239 -25.16513 1.000 10.98497 ? 111 GLN B O   1 
ATOM   2011 C CB  . GLN B 1 111 ? -4.12827  12.20903 -27.82195 1.000 10.46018 ? 111 GLN B CB  1 
ATOM   2012 C CG  . GLN B 1 111 ? -3.72775  13.64913 -28.12242 1.000 9.81297  ? 111 GLN B CG  1 
ATOM   2013 C CD  . GLN B 1 111 ? -2.73268  13.72895 -29.26871 1.000 14.88429 ? 111 GLN B CD  1 
ATOM   2014 O OE1 . GLN B 1 111 ? -2.97797  13.19161 -30.34852 1.000 13.45893 ? 111 GLN B OE1 1 
ATOM   2015 N NE2 . GLN B 1 111 ? -1.60722  14.39445 -29.04088 1.000 11.87674 ? 111 GLN B NE2 1 
ATOM   2016 N N   . MET B 1 112 ? -6.80091  13.00631 -25.36756 1.000 9.35294  ? 112 MET B N   1 
ATOM   2017 C CA  . MET B 1 112 ? -7.10236  13.73806 -24.13461 1.000 8.76569  ? 112 MET B CA  1 
ATOM   2018 C C   . MET B 1 112 ? -8.17909  13.03261 -23.32857 1.000 10.60247 ? 112 MET B C   1 
ATOM   2019 O O   . MET B 1 112 ? -9.28016  12.77361 -23.83004 1.000 13.11636 ? 112 MET B O   1 
ATOM   2020 C CB  . MET B 1 112 ? -7.54278  15.16645 -24.43586 1.000 9.70507  ? 112 MET B CB  1 
ATOM   2021 C CG  . MET B 1 112 ? -6.43340  15.98827 -25.08324 1.000 10.26945 ? 112 MET B CG  1 
ATOM   2022 S SD  . MET B 1 112 ? -6.99623  17.64814 -25.51693 1.000 11.83679 ? 112 MET B SD  1 
ATOM   2023 C CE  . MET B 1 112 ? -6.95470  18.40634 -23.89632 1.000 12.01238 ? 112 MET B CE  1 
ATOM   2024 N N   . VAL B 1 113 ? -7.86680  12.76580 -22.06626 1.000 9.00620  ? 113 VAL B N   1 
ATOM   2025 C CA  . VAL B 1 113 ? -8.72215  12.00230 -21.17320 1.000 10.99243 ? 113 VAL B CA  1 
ATOM   2026 C C   . VAL B 1 113 ? -8.98164  12.84062 -19.92621 1.000 8.51657  ? 113 VAL B C   1 
ATOM   2027 O O   . VAL B 1 113 ? -8.02824  13.23074 -19.24202 1.000 10.54986 ? 113 VAL B O   1 
ATOM   2028 C CB  . VAL B 1 113 ? -8.05084  10.66991 -20.80242 1.000 8.73727  ? 113 VAL B CB  1 
ATOM   2029 C CG1 . VAL B 1 113 ? -8.76369  9.99575  -19.65926 1.000 10.56964 ? 113 VAL B CG1 1 
ATOM   2030 C CG2 . VAL B 1 113 ? -7.95495  9.75036  -22.02906 1.000 11.01626 ? 113 VAL B CG2 1 
ATOM   2031 N N   . ASP B 1 114 ? -10.26753 13.11571 -19.63374 1.000 9.01867  ? 114 ASP B N   1 
ATOM   2032 C CA  . ASP B 1 114 ? -10.72812 13.74665 -18.39789 1.000 10.48174 ? 114 ASP B CA  1 
ATOM   2033 C C   . ASP B 1 114 ? -11.57856 12.73698 -17.63506 1.000 10.73524 ? 114 ASP B C   1 
ATOM   2034 O O   . ASP B 1 114 ? -12.42126 12.06407 -18.23598 1.000 12.29743 ? 114 ASP B O   1 
ATOM   2035 C CB  . ASP B 1 114 ? -11.61202 14.97923 -18.65778 1.000 8.57748  ? 114 ASP B CB  1 
ATOM   2036 C CG  . ASP B 1 114 ? -10.87563 16.16334 -19.22516 1.000 12.05692 ? 114 ASP B CG  1 
ATOM   2037 O OD1 . ASP B 1 114 ? -9.70782  16.05234 -19.60718 1.000 11.48051 ? 114 ASP B OD1 1 
ATOM   2038 O OD2 . ASP B 1 114 ? -11.51771 17.23453 -19.31685 1.000 13.80372 ? 114 ASP B OD2 1 
ATOM   2039 N N   . TYR B 1 115 ? -11.38942 12.64191 -16.30923 1.000 9.99325  ? 115 TYR B N   1 
ATOM   2040 C CA  . TYR B 1 115 ? -12.16821 11.69656 -15.48932 1.000 9.31124  ? 115 TYR B CA  1 
ATOM   2041 C C   . TYR B 1 115 ? -12.14715 10.28061 -16.07418 1.000 11.33895 ? 115 TYR B C   1 
ATOM   2042 O O   . TYR B 1 115 ? -13.15900 9.56755  -16.06344 1.000 13.19626 ? 115 TYR B O   1 
ATOM   2043 C CB  . TYR B 1 115 ? -13.62930 12.14054 -15.32572 1.000 9.56564  ? 115 TYR B CB  1 
ATOM   2044 C CG  . TYR B 1 115 ? -13.90227 13.44421 -14.60515 1.000 11.14409 ? 115 TYR B CG  1 
ATOM   2045 C CD1 . TYR B 1 115 ? -13.97156 14.65975 -15.29658 1.000 11.59508 ? 115 TYR B CD1 1 
ATOM   2046 C CD2 . TYR B 1 115 ? -14.16183 13.45501 -13.24546 1.000 13.15642 ? 115 TYR B CD2 1 
ATOM   2047 C CE1 . TYR B 1 115 ? -14.27121 15.84827 -14.63212 1.000 12.20630 ? 115 TYR B CE1 1 
ATOM   2048 C CE2 . TYR B 1 115 ? -14.46192 14.63769 -12.57920 1.000 16.95434 ? 115 TYR B CE2 1 
ATOM   2049 C CZ  . TYR B 1 115 ? -14.50955 15.82445 -13.27201 1.000 12.95285 ? 115 TYR B CZ  1 
ATOM   2050 O OH  . TYR B 1 115 ? -14.81907 16.97854 -12.58652 1.000 12.55866 ? 115 TYR B OH  1 
ATOM   2051 N N   . GLY B 1 116 ? -11.00026 9.87437  -16.62279 1.000 10.75247 ? 116 GLY B N   1 
ATOM   2052 C CA  . GLY B 1 116 ? -10.87390 8.54646  -17.19446 1.000 12.92959 ? 116 GLY B CA  1 
ATOM   2053 C C   . GLY B 1 116 ? -11.55873 8.31624  -18.53087 1.000 11.91259 ? 116 GLY B C   1 
ATOM   2054 O O   . GLY B 1 116 ? -11.53536 7.18037  -19.03177 1.000 12.74500 ? 116 GLY B O   1 
ATOM   2055 N N   . ARG B 1 117 ? -12.13924 9.34128  -19.14219 1.000 10.95199 ? 117 ARG B N   1 
ATOM   2056 C CA  . ARG B 1 117 ? -12.81344 9.20498  -20.42599 1.000 12.86667 ? 117 ARG B CA  1 
ATOM   2057 C C   . ARG B 1 117 ? -12.22365 10.13389 -21.46845 1.000 12.27895 ? 117 ARG B C   1 
ATOM   2058 O O   . ARG B 1 117 ? -11.81745 11.25695 -21.16641 1.000 11.60653 ? 117 ARG B O   1 
ATOM   2059 C CB  . ARG B 1 117 ? -14.29110 9.51666  -20.32275 1.000 15.78680 ? 117 ARG B CB  1 
ATOM   2060 C CG  . ARG B 1 117 ? -14.95249 8.81979  -19.21052 1.000 15.91753 ? 117 ARG B CG  1 
ATOM   2061 C CD  . ARG B 1 117 ? -14.94716 7.33994  -19.49190 1.000 19.27377 ? 117 ARG B CD  1 
ATOM   2062 N NE  . ARG B 1 117 ? -15.40794 7.12843  -20.84950 1.000 22.61620 ? 117 ARG B NE  1 
ATOM   2063 C CZ  . ARG B 1 117 ? -16.67002 6.87470  -21.10981 1.000 27.81979 ? 117 ARG B CZ  1 
ATOM   2064 N NH1 . ARG B 1 117 ? -17.57716 7.06273  -20.18530 1.000 31.99865 ? 117 ARG B NH1 1 
ATOM   2065 N NH2 . ARG B 1 117 ? -17.03655 6.53830  -22.34594 1.000 30.87726 ? 117 ARG B NH2 1 
ATOM   2066 N N   . PHE B 1 118 ? -12.20724 9.66125  -22.71155 1.000 10.64518 ? 118 PHE B N   1 
ATOM   2067 C CA  . PHE B 1 118 ? -11.79479 10.51766 -23.80767 1.000 12.92391 ? 118 PHE B CA  1 
ATOM   2068 C C   . PHE B 1 118 ? -12.79409 11.63762 -24.03232 1.000 11.55097 ? 118 PHE B C   1 
ATOM   2069 O O   . PHE B 1 118 ? -14.01131 11.43686 -23.97362 1.000 15.75058 ? 118 PHE B O   1 
ATOM   2070 C CB  . PHE B 1 118 ? -11.60667 9.70355  -25.08295 1.000 12.89645 ? 118 PHE B CB  1 
ATOM   2071 C CG  . PHE B 1 118 ? -10.39495 8.81540  -25.03725 1.000 15.74107 ? 118 PHE B CG  1 
ATOM   2072 C CD1 . PHE B 1 118 ? -10.47600 7.53171  -24.51669 1.000 19.39153 ? 118 PHE B CD1 1 
ATOM   2073 C CD2 . PHE B 1 118 ? -9.16484  9.28806  -25.45480 1.000 11.55487 ? 118 PHE B CD2 1 
ATOM   2074 C CE1 . PHE B 1 118 ? -9.34883  6.71839  -24.46003 1.000 18.16716 ? 118 PHE B CE1 1 
ATOM   2075 C CE2 . PHE B 1 118 ? -8.03780  8.48991  -25.39114 1.000 14.52037 ? 118 PHE B CE2 1 
ATOM   2076 C CZ  . PHE B 1 118 ? -8.12769  7.20108  -24.88895 1.000 15.83160 ? 118 PHE B CZ  1 
ATOM   2077 N N   . LEU B 1 119 ? -12.25581 12.82046 -24.29753 1.000 14.32540 ? 119 LEU B N   1 
ATOM   2078 C CA  . LEU B 1 119 ? -13.05315 14.01601 -24.49056 1.000 14.35067 ? 119 LEU B CA  1 
ATOM   2079 C C   . LEU B 1 119 ? -13.73964 13.99511 -25.84893 1.000 15.04875 ? 119 LEU B C   1 
ATOM   2080 O O   . LEU B 1 119 ? -13.25866 13.35269 -26.78635 1.000 14.96831 ? 119 LEU B O   1 
ATOM   2081 C CB  . LEU B 1 119 ? -12.15677 15.24423 -24.40007 1.000 11.78889 ? 119 LEU B CB  1 
ATOM   2082 C CG  . LEU B 1 119 ? -11.75618 15.65720 -22.98213 1.000 12.68651 ? 119 LEU B CG  1 
ATOM   2083 C CD1 . LEU B 1 119 ? -10.84627 16.87751 -23.05016 1.000 14.81707 ? 119 LEU B CD1 1 
ATOM   2084 C CD2 . LEU B 1 119 ? -13.02511 15.96273 -22.17448 1.000 15.42383 ? 119 LEU B CD2 1 
ATOM   2085 N N   . PRO B 1 120 ? -14.85793 14.71735 -25.98381 1.000 12.76812 ? 120 PRO B N   1 
ATOM   2086 C CA  . PRO B 1 120 ? -15.45093 14.94189 -27.30786 1.000 14.40335 ? 120 PRO B CA  1 
ATOM   2087 C C   . PRO B 1 120 ? -14.81953 16.14068 -27.99413 1.000 18.38833 ? 120 PRO B C   1 
ATOM   2088 O O   . PRO B 1 120 ? -13.98317 16.81677 -27.38906 1.000 18.59699 ? 120 PRO B O   1 
ATOM   2089 C CB  . PRO B 1 120 ? -16.91777 15.20748 -26.97609 1.000 14.33159 ? 120 PRO B CB  1 
ATOM   2090 C CG  . PRO B 1 120 ? -16.84431 15.91148 -25.60611 1.000 12.42130 ? 120 PRO B CG  1 
ATOM   2091 C CD  . PRO B 1 120 ? -15.59537 15.41354 -24.91349 1.000 12.26044 ? 120 PRO B CD  1 
ATOM   2092 N N   . GLN B 1 121 ? -15.23556 16.43757 -29.22109 1.000 23.24021 ? 121 GLN B N   1 
ATOM   2093 C CA  . GLN B 1 121 ? -14.81231 17.66917 -29.86207 1.000 19.84850 ? 121 GLN B CA  1 
ATOM   2094 C C   . GLN B 1 121 ? -15.46188 18.87948 -29.18653 1.000 20.10978 ? 121 GLN B C   1 
ATOM   2095 O O   . GLN B 1 121 ? -16.55802 18.77574 -28.63031 1.000 18.03745 ? 121 GLN B O   1 
ATOM   2096 C CB  . GLN B 1 121 ? -15.17419 17.64198 -31.34144 1.000 22.20292 ? 121 GLN B CB  1 
ATOM   2097 C CG  . GLN B 1 121 ? -14.58692 16.43041 -32.06763 1.000 24.00510 ? 121 GLN B CG  1 
ATOM   2098 C CD  . GLN B 1 121 ? -13.07692 16.51582 -32.26673 1.000 27.95135 ? 121 GLN B CD  1 
ATOM   2099 O OE1 . GLN B 1 121 ? -12.43001 15.51926 -32.60713 1.000 29.80067 ? 121 GLN B OE1 1 
ATOM   2100 N NE2 . GLN B 1 121 ? -12.50963 17.70007 -32.05720 1.000 26.13004 ? 121 GLN B NE2 1 
ATOM   2101 N N   . PRO B 1 122 ? -14.80600 20.04115 -29.23251 1.000 19.05721 ? 122 PRO B N   1 
ATOM   2102 C CA  . PRO B 1 122 ? -15.38682 21.24389 -28.62971 1.000 17.19064 ? 122 PRO B CA  1 
ATOM   2103 C C   . PRO B 1 122 ? -16.79963 21.49051 -29.12970 1.000 21.23516 ? 122 PRO B C   1 
ATOM   2104 O O   . PRO B 1 122 ? -17.09127 21.36569 -30.32318 1.000 24.12626 ? 122 PRO B O   1 
ATOM   2105 C CB  . PRO B 1 122 ? -14.43167 22.35479 -29.08180 1.000 18.40419 ? 122 PRO B CB  1 
ATOM   2106 C CG  . PRO B 1 122 ? -13.12396 21.66561 -29.16097 1.000 17.84809 ? 122 PRO B CG  1 
ATOM   2107 C CD  . PRO B 1 122 ? -13.47348 20.31582 -29.79284 1.000 17.67771 ? 122 PRO B CD  1 
ATOM   2108 N N   . GLY B 1 123 ? -17.68599 21.82758 -28.19716 1.000 23.20901 ? 123 GLY B N   1 
ATOM   2109 C CA  . GLY B 1 123 ? -19.06281 22.10940 -28.51223 1.000 22.88861 ? 123 GLY B CA  1 
ATOM   2110 C C   . GLY B 1 123 ? -19.99760 20.93380 -28.36147 1.000 21.98321 ? 123 GLY B C   1 
ATOM   2111 O O   . GLY B 1 123 ? -21.21907 21.13199 -28.30971 1.000 26.10556 ? 123 GLY B O   1 
ATOM   2112 N N   . HIS B 1 124 ? -19.46500 19.71930 -28.27651 1.000 20.49882 ? 124 HIS B N   1 
ATOM   2113 C CA  . HIS B 1 124 ? -20.27787 18.51500 -28.16956 1.000 23.59467 ? 124 HIS B CA  1 
ATOM   2114 C C   . HIS B 1 124 ? -20.23381 17.91280 -26.77502 1.000 17.42199 ? 124 HIS B C   1 
ATOM   2115 O O   . HIS B 1 124 ? -20.40832 16.70359 -26.61249 1.000 21.34358 ? 124 HIS B O   1 
ATOM   2116 C CB  . HIS B 1 124 ? -19.85262 17.48349 -29.21026 1.000 28.04488 ? 124 HIS B CB  1 
ATOM   2117 C CG  . HIS B 1 124 ? -20.03273 17.95080 -30.61680 1.000 27.50689 ? 124 HIS B CG  1 
ATOM   2118 N ND1 . HIS B 1 124 ? -19.41823 19.08019 -31.11522 1.000 33.06032 ? 124 HIS B ND1 1 
ATOM   2119 C CD2 . HIS B 1 124 ? -20.79323 17.45946 -31.62268 1.000 31.45748 ? 124 HIS B CD2 1 
ATOM   2120 C CE1 . HIS B 1 124 ? -19.77181 19.24941 -32.37643 1.000 27.88129 ? 124 HIS B CE1 1 
ATOM   2121 N NE2 . HIS B 1 124 ? -20.61010 18.28204 -32.70703 1.000 35.42652 ? 124 HIS B NE2 1 
ATOM   2122 N N   . GLU B 1 125 ? -20.03756 18.75616 -25.75788 1.000 15.89962 ? 125 GLU B N   1 
ATOM   2123 C CA  . GLU B 1 125 ? -19.96756 18.26810 -24.38801 1.000 17.85439 ? 125 GLU B CA  1 
ATOM   2124 C C   . GLU B 1 125 ? -21.31761 17.77393 -23.87711 1.000 17.47578 ? 125 GLU B C   1 
ATOM   2125 O O   . GLU B 1 125 ? -21.35649 16.91505 -22.98962 1.000 19.29895 ? 125 GLU B O   1 
ATOM   2126 C CB  . GLU B 1 125 ? -19.42115 19.36666 -23.46690 1.000 18.81586 ? 125 GLU B CB  1 
ATOM   2127 C CG  . GLU B 1 125 ? -17.98826 19.81386 -23.76526 1.000 19.55856 ? 125 GLU B CG  1 
ATOM   2128 C CD  . GLU B 1 125 ? -17.88150 20.73534 -24.97776 1.000 20.95713 ? 125 GLU B CD  1 
ATOM   2129 O OE1 . GLU B 1 125 ? -18.91954 21.25960 -25.42261 1.000 21.52629 ? 125 GLU B OE1 1 
ATOM   2130 O OE2 . GLU B 1 125 ? -16.75147 20.96593 -25.45360 1.000 18.75848 ? 125 GLU B OE2 1 
ATOM   2131 N N   . GLY B 1 126 ? -22.42630 18.30366 -24.39868 1.000 22.91131 ? 126 GLY B N   1 
ATOM   2132 C CA  . GLY B 1 126 ? -23.73352 17.85366 -23.93290 1.000 19.14731 ? 126 GLY B CA  1 
ATOM   2133 C C   . GLY B 1 126 ? -24.01982 16.40535 -24.29031 1.000 21.57737 ? 126 GLY B C   1 
ATOM   2134 O O   . GLY B 1 126 ? -24.41972 15.60558 -23.43096 1.000 21.83785 ? 126 GLY B O   1 
ATOM   2135 N N   . GLU B 1 127 ? -23.82207 16.04710 -25.56344 1.000 20.39793 ? 127 GLU B N   1 
ATOM   2136 C CA  . GLU B 1 127 ? -24.06108 14.67439 -26.00410 1.000 23.90444 ? 127 GLU B CA  1 
ATOM   2137 C C   . GLU B 1 127 ? -23.09407 13.70170 -25.33706 1.000 24.09211 ? 127 GLU B C   1 
ATOM   2138 O O   . GLU B 1 127 ? -23.48228 12.59757 -24.93701 1.000 21.02517 ? 127 GLU B O   1 
ATOM   2139 C CB  . GLU B 1 127 ? -23.94819 14.58642 -27.52965 1.000 26.13935 ? 127 GLU B CB  1 
ATOM   2140 C CG  . GLU B 1 127 ? -23.59176 13.19497 -28.07677 1.000 29.25823 ? 127 GLU B CG  1 
ATOM   2141 C CD  . GLU B 1 127 ? -22.91638 13.23519 -29.44418 1.000 42.74279 ? 127 GLU B CD  1 
ATOM   2142 O OE1 . GLU B 1 127 ? -22.44073 14.31995 -29.85088 1.000 44.43843 ? 127 GLU B OE1 1 
ATOM   2143 O OE2 . GLU B 1 127 ? -22.85721 12.17552 -30.11364 1.000 48.35820 ? 127 GLU B OE2 1 
ATOM   2144 N N   . TRP B 1 128 ? -21.82702 14.09585 -25.22507 1.000 19.15331 ? 128 TRP B N   1 
ATOM   2145 C CA  . TRP B 1 128 ? -20.83080 13.28385 -24.53341 1.000 15.23631 ? 128 TRP B CA  1 
ATOM   2146 C C   . TRP B 1 128 ? -21.23565 13.02431 -23.09292 1.000 16.96224 ? 128 TRP B C   1 
ATOM   2147 O O   . TRP B 1 128 ? -21.14486 11.89523 -22.59792 1.000 16.18596 ? 128 TRP B O   1 
ATOM   2148 C CB  . TRP B 1 128 ? -19.50077 14.02384 -24.58787 1.000 15.80454 ? 128 TRP B CB  1 
ATOM   2149 C CG  . TRP B 1 128 ? -18.36672 13.46327 -23.80927 1.000 15.36203 ? 128 TRP B CG  1 
ATOM   2150 C CD1 . TRP B 1 128 ? -17.46182 12.53010 -24.24022 1.000 12.76283 ? 128 TRP B CD1 1 
ATOM   2151 C CD2 . TRP B 1 128 ? -17.95214 13.84749 -22.49777 1.000 14.12805 ? 128 TRP B CD2 1 
ATOM   2152 N NE1 . TRP B 1 128 ? -16.51659 12.30872 -23.27118 1.000 14.02818 ? 128 TRP B NE1 1 
ATOM   2153 C CE2 . TRP B 1 128 ? -16.80119 13.09135 -22.18552 1.000 13.92462 ? 128 TRP B CE2 1 
ATOM   2154 C CE3 . TRP B 1 128 ? -18.44301 14.74814 -21.55057 1.000 16.22358 ? 128 TRP B CE3 1 
ATOM   2155 C CZ2 . TRP B 1 128 ? -16.13637 13.21665 -20.97260 1.000 12.14011 ? 128 TRP B CZ2 1 
ATOM   2156 C CZ3 . TRP B 1 128 ? -17.78400 14.85995 -20.34127 1.000 17.25478 ? 128 TRP B CZ3 1 
ATOM   2157 C CH2 . TRP B 1 128 ? -16.64653 14.09913 -20.06447 1.000 18.31183 ? 128 TRP B CH2 1 
ATOM   2158 N N   . PHE B 1 129 ? -21.67950 14.07203 -22.39552 1.000 16.73293 ? 129 PHE B N   1 
ATOM   2159 C CA  . PHE B 1 129 ? -22.04101 13.90853 -20.99107 1.000 15.64188 ? 129 PHE B CA  1 
ATOM   2160 C C   . PHE B 1 129 ? -23.26359 13.01108 -20.85838 1.000 15.64034 ? 129 PHE B C   1 
ATOM   2161 O O   . PHE B 1 129 ? -23.33700 12.16799 -19.95739 1.000 19.76955 ? 129 PHE B O   1 
ATOM   2162 C CB  . PHE B 1 129 ? -22.28705 15.28106 -20.36011 1.000 18.97429 ? 129 PHE B CB  1 
ATOM   2163 C CG  . PHE B 1 129 ? -22.65796 15.22546 -18.91688 1.000 18.23321 ? 129 PHE B CG  1 
ATOM   2164 C CD1 . PHE B 1 129 ? -21.69127 14.95469 -17.95138 1.000 17.30658 ? 129 PHE B CD1 1 
ATOM   2165 C CD2 . PHE B 1 129 ? -23.97237 15.42630 -18.51711 1.000 18.08192 ? 129 PHE B CD2 1 
ATOM   2166 C CE1 . PHE B 1 129 ? -22.02128 14.89281 -16.61316 1.000 17.59956 ? 129 PHE B CE1 1 
ATOM   2167 C CE2 . PHE B 1 129 ? -24.31103 15.37435 -17.17986 1.000 17.36865 ? 129 PHE B CE2 1 
ATOM   2168 C CZ  . PHE B 1 129 ? -23.32820 15.10197 -16.22195 1.000 15.08765 ? 129 PHE B CZ  1 
ATOM   2169 N N   . ASP B 1 130 ? -24.20338 13.14337 -21.78569 1.000 17.44638 ? 130 ASP B N   1 
ATOM   2170 C CA  . ASP B 1 130 ? -25.41184 12.33948 -21.73476 1.000 21.93612 ? 130 ASP B CA  1 
ATOM   2171 C C   . ASP B 1 130 ? -25.10382 10.84969 -21.88869 1.000 25.35345 ? 130 ASP B C   1 
ATOM   2172 O O   . ASP B 1 130 ? -25.81925 10.01641 -21.31961 1.000 28.82536 ? 130 ASP B O   1 
ATOM   2173 C CB  . ASP B 1 130 ? -26.37324 12.82528 -22.82109 1.000 23.82131 ? 130 ASP B CB  1 
ATOM   2174 C CG  . ASP B 1 130 ? -27.14590 14.07065 -22.39771 1.000 27.81171 ? 130 ASP B CG  1 
ATOM   2175 O OD1 . ASP B 1 130 ? -27.03732 14.47117 -21.22046 1.000 27.88746 ? 130 ASP B OD1 1 
ATOM   2176 O OD2 . ASP B 1 130 ? -27.82093 14.68364 -23.25412 1.000 30.04136 ? 130 ASP B OD2 1 
ATOM   2177 N N   . ASN B 1 131 ? -24.03566 10.48217 -22.61044 1.000 16.49680 ? 131 ASN B N   1 
ATOM   2178 C CA  . ASN B 1 131 ? -23.79528 9.07644  -22.93461 1.000 16.94405 ? 131 ASN B CA  1 
ATOM   2179 C C   . ASN B 1 131 ? -22.64660 8.43830  -22.15424 1.000 24.94383 ? 131 ASN B C   1 
ATOM   2180 O O   . ASN B 1 131 ? -21.89388 7.62670  -22.68997 1.000 37.49109 ? 131 ASN B O   1 
ATOM   2181 C CB  . ASN B 1 131 ? -23.56488 8.86418  -24.43386 1.000 29.92602 ? 131 ASN B CB  1 
ATOM   2182 C CG  . ASN B 1 131 ? -23.44410 7.36048  -24.80639 1.000 32.87225 ? 131 ASN B CG  1 
ATOM   2183 O OD1 . ASN B 1 131 ? -22.45754 6.93103  -25.42035 1.000 31.99433 ? 131 ASN B OD1 1 
ATOM   2184 N ND2 . ASN B 1 131 ? -24.44332 6.55842  -24.39786 1.000 33.46677 ? 131 ASN B ND2 1 
ATOM   2185 N N   . LEU B 1 132 ? -22.48495 8.72994  -20.87439 1.000 25.64946 ? 132 LEU B N   1 
ATOM   2186 C CA  . LEU B 1 132 ? -22.11793 7.59160  -20.04355 1.000 35.22073 ? 132 LEU B CA  1 
ATOM   2187 C C   . LEU B 1 132 ? -22.76919 7.70206  -18.68678 1.000 18.24462 ? 132 LEU B C   1 
ATOM   2188 O O   . LEU B 1 132 ? -23.84616 8.28439  -18.50812 1.000 17.21418 ? 132 LEU B O   1 
ATOM   2189 C CB  . LEU B 1 132 ? -20.62405 7.26159  -19.85064 1.000 34.91370 ? 132 LEU B CB  1 
ATOM   2190 C CG  . LEU B 1 132 ? -20.24920 5.91019  -20.54367 1.000 25.94081 ? 132 LEU B CG  1 
ATOM   2191 C CD1 . LEU B 1 132 ? -19.31996 4.98483  -19.72307 1.000 36.69192 ? 132 LEU B CD1 1 
ATOM   2192 C CD2 . LEU B 1 132 ? -21.37491 5.09300  -20.88586 1.000 33.02379 ? 132 LEU B CD2 1 
ATOM   2193 N N   . SER B 1 133 ? -22.14937 6.99753  -17.76384 1.000 18.02977 ? 133 SER B N   1 
ATOM   2194 C CA  . SER B 1 133 ? -22.96346 6.26102  -16.83776 1.000 14.39966 ? 133 SER B CA  1 
ATOM   2195 C C   . SER B 1 133 ? -23.47824 7.18770  -15.76819 1.000 18.89944 ? 133 SER B C   1 
ATOM   2196 O O   . SER B 1 133 ? -22.92720 8.26332  -15.52034 1.000 14.73692 ? 133 SER B O   1 
ATOM   2197 C CB  . SER B 1 133 ? -22.17323 5.12412  -16.21333 1.000 16.40505 ? 133 SER B CB  1 
ATOM   2198 O OG  . SER B 1 133 ? -21.03134 5.63433  -15.56194 1.000 17.63488 ? 133 SER B OG  1 
ATOM   2199 N N   . SER B 1 134 ? -24.56275 6.74736  -15.14134 1.000 15.18769 ? 134 SER B N   1 
ATOM   2200 C CA  . SER B 1 134 ? -25.16220 7.50139  -14.05167 1.000 16.22590 ? 134 SER B CA  1 
ATOM   2201 C C   . SER B 1 134 ? -24.14635 7.82536  -12.96870 1.000 15.84601 ? 134 SER B C   1 
ATOM   2202 O O   . SER B 1 134 ? -24.11375 8.95321  -12.45835 1.000 17.74037 ? 134 SER B O   1 
ATOM   2203 C CB  . SER B 1 134 ? -26.33116 6.70424  -13.47435 1.000 20.87220 ? 134 SER B CB  1 
ATOM   2204 O OG  . SER B 1 134 ? -27.23447 6.38013  -14.50878 1.000 29.42929 ? 134 SER B OG  1 
ATOM   2205 N N   . ASP B 1 135 ? -23.30429 6.85051  -12.60442 1.000 15.51517 ? 135 ASP B N   1 
ATOM   2206 C CA  . ASP B 1 135 ? -22.33108 7.08679  -11.54821 1.000 19.98975 ? 135 ASP B CA  1 
ATOM   2207 C C   . ASP B 1 135 ? -21.33165 8.14887  -11.97394 1.000 15.36686 ? 135 ASP B C   1 
ATOM   2208 O O   . ASP B 1 135 ? -20.95530 9.01446  -11.17500 1.000 17.31543 ? 135 ASP B O   1 
ATOM   2209 C CB  . ASP B 1 135 ? -21.59471 5.79459  -11.19692 1.000 20.42580 ? 135 ASP B CB  1 
ATOM   2210 C CG  . ASP B 1 135 ? -22.37656 4.91232  -10.24715 1.000 23.47685 ? 135 ASP B CG  1 
ATOM   2211 O OD1 . ASP B 1 135 ? -23.33221 5.39952  -9.59967  1.000 25.57341 ? 135 ASP B OD1 1 
ATOM   2212 O OD2 . ASP B 1 135 ? -22.01180 3.72481  -10.13988 1.000 29.34381 ? 135 ASP B OD2 1 
ATOM   2213 N N   . GLU B 1 136 ? -20.89836 8.09533  -13.23251 1.000 15.68775 ? 136 GLU B N   1 
ATOM   2214 C CA  . GLU B 1 136 ? -19.92533 9.06654  -13.72566 1.000 13.86093 ? 136 GLU B CA  1 
ATOM   2215 C C   . GLU B 1 136 ? -20.51017 10.47234 -13.75533 1.000 16.73171 ? 136 GLU B C   1 
ATOM   2216 O O   . GLU B 1 136 ? -19.83903 11.43876 -13.36767 1.000 16.43390 ? 136 GLU B O   1 
ATOM   2217 C CB  . GLU B 1 136 ? -19.45378 8.65859  -15.11938 1.000 14.61066 ? 136 GLU B CB  1 
ATOM   2218 C CG  . GLU B 1 136 ? -18.39567 7.57224  -15.12299 1.000 17.81830 ? 136 GLU B CG  1 
ATOM   2219 C CD  . GLU B 1 136 ? -18.16176 7.03930  -16.51375 1.000 22.76461 ? 136 GLU B CD  1 
ATOM   2220 O OE1 . GLU B 1 136 ? -19.06404 6.36526  -17.03966 1.000 20.19193 ? 136 GLU B OE1 1 
ATOM   2221 O OE2 . GLU B 1 136 ? -17.10102 7.33390  -17.10640 1.000 16.95383 ? 136 GLU B OE2 1 
ATOM   2222 N N   . ARG B 1 137 ? -21.74953 10.60837 -14.23942 1.000 13.53817 ? 137 ARG B N   1 
ATOM   2223 C CA  . ARG B 1 137 ? -22.39193 11.91846 -14.27921 1.000 13.86433 ? 137 ARG B CA  1 
ATOM   2224 C C   . ARG B 1 137 ? -22.54304 12.46202 -12.87221 1.000 16.51149 ? 137 ARG B C   1 
ATOM   2225 O O   . ARG B 1 137 ? -22.23489 13.62921 -12.61420 1.000 14.64045 ? 137 ARG B O   1 
ATOM   2226 C CB  . ARG B 1 137 ? -23.75534 11.82242 -14.96568 1.000 14.76917 ? 137 ARG B CB  1 
ATOM   2227 C CG  . ARG B 1 137 ? -23.71437 11.34134 -16.41102 1.000 15.35402 ? 137 ARG B CG  1 
ATOM   2228 C CD  . ARG B 1 137 ? -24.97325 11.72110 -17.16961 1.000 22.64046 ? 137 ARG B CD  1 
ATOM   2229 N NE  . ARG B 1 137 ? -26.17210 11.32644 -16.43824 1.000 20.54733 ? 137 ARG B NE  1 
ATOM   2230 C CZ  . ARG B 1 137 ? -26.76637 10.13875 -16.52864 1.000 31.46821 ? 137 ARG B CZ  1 
ATOM   2231 N NH1 . ARG B 1 137 ? -26.23803 9.14857  -17.22979 1.000 22.08672 ? 137 ARG B NH1 1 
ATOM   2232 N NH2 . ARG B 1 137 ? -27.90765 9.93069  -15.87444 1.000 33.12068 ? 137 ARG B NH2 1 
ATOM   2233 N N   . ALA B 1 138 ? -22.98618 11.61265 -11.93984 1.000 17.99437 ? 138 ALA B N   1 
ATOM   2234 C CA  . ALA B 1 138 ? -23.13073 12.04527 -10.55391 1.000 15.44154 ? 138 ALA B CA  1 
ATOM   2235 C C   . ALA B 1 138 ? -21.81519 12.56180 -9.99426  1.000 16.32714 ? 138 ALA B C   1 
ATOM   2236 O O   . ALA B 1 138 ? -21.78661 13.60573 -9.33400  1.000 16.42070 ? 138 ALA B O   1 
ATOM   2237 C CB  . ALA B 1 138 ? -23.65586 10.89734 -9.69474  1.000 15.55572 ? 138 ALA B CB  1 
ATOM   2238 N N   . PHE B 1 139 ? -20.71730 11.84472 -10.24537 1.000 13.38686 ? 139 PHE B N   1 
ATOM   2239 C CA  . PHE B 1 139 ? -19.43073 12.27748 -9.71105  1.000 17.77056 ? 139 PHE B CA  1 
ATOM   2240 C C   . PHE B 1 139 ? -19.02171 13.62517 -10.28687 1.000 15.19333 ? 139 PHE B C   1 
ATOM   2241 O O   . PHE B 1 139 ? -18.54877 14.50378 -9.55406  1.000 15.00445 ? 139 PHE B O   1 
ATOM   2242 C CB  . PHE B 1 139 ? -18.34513 11.24640 -10.00005 1.000 15.86774 ? 139 PHE B CB  1 
ATOM   2243 C CG  . PHE B 1 139 ? -17.01301 11.62673 -9.44123  1.000 18.29998 ? 139 PHE B CG  1 
ATOM   2244 C CD1 . PHE B 1 139 ? -16.87146 11.92673 -8.09804  1.000 21.75054 ? 139 PHE B CD1 1 
ATOM   2245 C CD2 . PHE B 1 139 ? -15.92866 11.79519 -10.27642 1.000 15.38884 ? 139 PHE B CD2 1 
ATOM   2246 C CE1 . PHE B 1 139 ? -15.64031 12.31121 -7.58532  1.000 25.88574 ? 139 PHE B CE1 1 
ATOM   2247 C CE2 . PHE B 1 139 ? -14.69972 12.17293 -9.78042  1.000 18.29186 ? 139 PHE B CE2 1 
ATOM   2248 C CZ  . PHE B 1 139 ? -14.55534 12.44367 -8.43269  1.000 22.28181 ? 139 PHE B CZ  1 
ATOM   2249 N N   . MET B 1 140 ? -19.19596 13.81611 -11.59635 1.000 15.09262 ? 140 MET B N   1 
ATOM   2250 C CA  . MET B 1 140 ? -18.80499 15.09506 -12.17680 1.000 12.62847 ? 140 MET B CA  1 
ATOM   2251 C C   . MET B 1 140 ? -19.65122 16.22359 -11.60195 1.000 15.01482 ? 140 MET B C   1 
ATOM   2252 O O   . MET B 1 140 ? -19.14720 17.32048 -11.34512 1.000 14.84117 ? 140 MET B O   1 
ATOM   2253 C CB  . MET B 1 140 ? -18.94442 15.07324 -13.69911 1.000 15.74461 ? 140 MET B CB  1 
ATOM   2254 C CG  . MET B 1 140 ? -17.98793 14.11874 -14.36192 1.000 14.78992 ? 140 MET B CG  1 
ATOM   2255 S SD  . MET B 1 140 ? -18.37183 13.93620 -16.10825 1.000 17.51343 ? 140 MET B SD  1 
ATOM   2256 C CE  . MET B 1 140 ? -16.82772 13.29434 -16.76194 1.000 17.98038 ? 140 MET B CE  1 
ATOM   2257 N N   . GLU B 1 141 ? -20.94755 15.97671 -11.39554 1.000 15.38996 ? 141 GLU B N   1 
ATOM   2258 C CA  . GLU B 1 141 ? -21.81002 17.03800 -10.88490 1.000 18.53118 ? 141 GLU B CA  1 
ATOM   2259 C C   . GLU B 1 141 ? -21.49048 17.44364 -9.44533  1.000 18.77331 ? 141 GLU B C   1 
ATOM   2260 O O   . GLU B 1 141 ? -21.90583 18.53488 -9.02947  1.000 21.14481 ? 141 GLU B O   1 
ATOM   2261 C CB  . GLU B 1 141 ? -23.28565 16.64067 -11.02429 1.000 19.54247 ? 141 GLU B CB  1 
ATOM   2262 C CG  . GLU B 1 141 ? -23.69618 16.41698 -12.46606 1.000 20.02166 ? 141 GLU B CG  1 
ATOM   2263 C CD  . GLU B 1 141 ? -25.06759 15.78957 -12.60001 1.000 25.91892 ? 141 GLU B CD  1 
ATOM   2264 O OE1 . GLU B 1 141 ? -25.53676 15.15510 -11.62570 1.000 26.72024 ? 141 GLU B OE1 1 
ATOM   2265 O OE2 . GLU B 1 141 ? -25.67354 15.93308 -13.68072 1.000 28.46922 ? 141 GLU B OE2 1 
ATOM   2266 N N   . THR B 1 142 ? -20.74121 16.63140 -8.68698  1.000 18.18936 ? 142 THR B N   1 
ATOM   2267 C CA  . THR B 1 142 ? -20.25160 17.11331 -7.39568  1.000 15.46966 ? 142 THR B CA  1 
ATOM   2268 C C   . THR B 1 142 ? -19.21613 18.22465 -7.54527  1.000 18.98313 ? 142 THR B C   1 
ATOM   2269 O O   . THR B 1 142 ? -19.00403 18.99110 -6.59592  1.000 18.61066 ? 142 THR B O   1 
ATOM   2270 C CB  . THR B 1 142 ? -19.66553 15.96949 -6.54401  1.000 18.70048 ? 142 THR B CB  1 
ATOM   2271 O OG1 . THR B 1 142 ? -18.38874 15.53991 -7.05235  1.000 18.27506 ? 142 THR B OG1 1 
ATOM   2272 C CG2 . THR B 1 142 ? -20.63357 14.78940 -6.43378  1.000 16.16661 ? 142 THR B CG2 1 
ATOM   2273 N N   . ASN B 1 143 ? -18.58159 18.33888 -8.70667  1.000 16.80594 ? 143 ASN B N   1 
ATOM   2274 C CA  . ASN B 1 143 ? -17.48703 19.29176 -8.90077  1.000 17.30507 ? 143 ASN B CA  1 
ATOM   2275 C C   . ASN B 1 143 ? -17.98360 20.53609 -9.63089  1.000 16.12114 ? 143 ASN B C   1 
ATOM   2276 O O   . ASN B 1 143 ? -17.50873 20.90372 -10.70474 1.000 19.01138 ? 143 ASN B O   1 
ATOM   2277 C CB  . ASN B 1 143 ? -16.34125 18.61982 -9.64832  1.000 12.90922 ? 143 ASN B CB  1 
ATOM   2278 C CG  . ASN B 1 143 ? -15.66226 17.57186 -8.81397  1.000 15.46129 ? 143 ASN B CG  1 
ATOM   2279 O OD1 . ASN B 1 143 ? -15.54807 17.71846 -7.59253  1.000 19.39178 ? 143 ASN B OD1 1 
ATOM   2280 N ND2 . ASN B 1 143 ? -15.21728 16.49964 -9.45234  1.000 18.98021 ? 143 ASN B ND2 1 
ATOM   2281 N N   . VAL B 1 144 ? -18.97762 21.18437 -9.02046  1.000 16.81668 ? 144 VAL B N   1 
ATOM   2282 C CA  . VAL B 1 144 ? -19.56242 22.42038 -9.53613  1.000 19.06594 ? 144 VAL B CA  1 
ATOM   2283 C C   . VAL B 1 144 ? -19.71566 23.39180 -8.37523  1.000 23.09195 ? 144 VAL B C   1 
ATOM   2284 O O   . VAL B 1 144 ? -20.47825 23.12636 -7.43934  1.000 21.42838 ? 144 VAL B O   1 
ATOM   2285 C CB  . VAL B 1 144 ? -20.92459 22.18926 -10.21634 1.000 20.70565 ? 144 VAL B CB  1 
ATOM   2286 C CG1 . VAL B 1 144 ? -21.37080 23.45466 -10.94658 1.000 24.07005 ? 144 VAL B CG1 1 
ATOM   2287 C CG2 . VAL B 1 144 ? -20.83044 21.04414 -11.20632 1.000 19.47043 ? 144 VAL B CG2 1 
ATOM   2288 N N   . ASP B 1 145 ? -18.99236 24.50793 -8.43553  1.000 24.78788 ? 145 ASP B N   1 
ATOM   2289 C CA  . ASP B 1 145 ? -19.11297 25.62030 -7.49621  1.000 28.82362 ? 145 ASP B CA  1 
ATOM   2290 C C   . ASP B 1 145 ? -19.64929 26.81860 -8.26698  1.000 28.26137 ? 145 ASP B C   1 
ATOM   2291 O O   . ASP B 1 145 ? -18.95743 27.36930 -9.12829  1.000 36.86816 ? 145 ASP B O   1 
ATOM   2292 C CB  . ASP B 1 145 ? -17.76097 25.91955 -6.84285  1.000 20.52814 ? 145 ASP B CB  1 
ATOM   2293 C CG  . ASP B 1 145 ? -17.82041 27.05250 -5.82980  1.000 28.86207 ? 145 ASP B CG  1 
ATOM   2294 O OD1 . ASP B 1 145 ? -18.78491 27.84362 -5.82140  1.000 32.61333 ? 145 ASP B OD1 1 
ATOM   2295 O OD2 . ASP B 1 145 ? -16.91160 27.11233 -4.98633  1.000 25.18371 ? 145 ASP B OD2 1 
ATOM   2296 N N   . VAL B 1 146 ? -20.87312 27.22085 -7.95574  1.000 37.66141 ? 146 VAL B N   1 
ATOM   2297 C CA  . VAL B 1 146 ? -21.52809 28.34536 -8.62288  1.000 44.08497 ? 146 VAL B CA  1 
ATOM   2298 C C   . VAL B 1 146 ? -21.88504 29.33559 -7.51845  1.000 43.26798 ? 146 VAL B C   1 
ATOM   2299 O O   . VAL B 1 146 ? -22.96944 29.28757 -6.92843  1.000 54.43096 ? 146 VAL B O   1 
ATOM   2300 C CB  . VAL B 1 146 ? -22.75570 27.91017 -9.43203  1.000 44.98086 ? 146 VAL B CB  1 
ATOM   2301 C CG1 . VAL B 1 146 ? -23.63726 29.10447 -9.81321  1.000 47.30338 ? 146 VAL B CG1 1 
ATOM   2302 C CG2 . VAL B 1 146 ? -22.32684 27.13062 -10.67297 1.000 34.15700 ? 146 VAL B CG2 1 
ATOM   2303 N N   . SER B 1 147 ? -20.94588 30.22281 -7.20271  1.000 50.19810 ? 147 SER B N   1 
ATOM   2304 C CA  . SER B 1 147 ? -21.13655 31.23432 -6.16510  1.000 49.71655 ? 147 SER B CA  1 
ATOM   2305 C C   . SER B 1 147 ? -19.99562 32.24047 -6.20063  1.000 48.70422 ? 147 SER B C   1 
ATOM   2306 O O   . SER B 1 147 ? -20.16154 33.39608 -5.81386  1.000 60.57873 ? 147 SER B O   1 
ATOM   2307 C CB  . SER B 1 147 ? -21.23069 30.59176 -4.77511  1.000 50.03575 ? 147 SER B CB  1 
ATOM   2308 O OG  . SER B 1 147 ? -19.96108 30.16584 -4.30845  1.000 49.62322 ? 147 SER B OG  1 
ATOM   2309 N N   . PRO C 1 1   ? 10.11886  33.76793 -23.80682 1.000 15.16842 ? 1   PRO C N   1 
ATOM   2310 C CA  . PRO C 1 1   ? 9.75040   32.36855 -23.58789 1.000 14.90082 ? 1   PRO C CA  1 
ATOM   2311 C C   . PRO C 1 1   ? 9.39236   32.05759 -22.16204 1.000 11.20272 ? 1   PRO C C   1 
ATOM   2312 O O   . PRO C 1 1   ? 9.67169   32.85781 -21.27774 1.000 10.73073 ? 1   PRO C O   1 
ATOM   2313 C CB  . PRO C 1 1   ? 11.01863  31.60331 -23.98737 1.000 13.50733 ? 1   PRO C CB  1 
ATOM   2314 C CG  . PRO C 1 1   ? 12.13954  32.58387 -23.84784 1.000 14.30779 ? 1   PRO C CG  1 
ATOM   2315 C CD  . PRO C 1 1   ? 11.55933  33.94196 -24.09183 1.000 16.60323 ? 1   PRO C CD  1 
ATOM   2316 N N   . VAL C 1 2   ? 8.79734   30.89374 -21.93081 1.000 8.17479  ? 2   VAL C N   1 
ATOM   2317 C CA  . VAL C 1 2   ? 8.77520   30.31337 -20.58989 1.000 6.77325  ? 2   VAL C CA  1 
ATOM   2318 C C   . VAL C 1 2   ? 9.55469   29.01676 -20.65557 1.000 9.45397  ? 2   VAL C C   1 
ATOM   2319 O O   . VAL C 1 2   ? 9.22632   28.13205 -21.45396 1.000 8.46251  ? 2   VAL C O   1 
ATOM   2320 C CB  . VAL C 1 2   ? 7.35563   30.06968 -20.06634 1.000 10.35505 ? 2   VAL C CB  1 
ATOM   2321 C CG1 . VAL C 1 2   ? 7.43951   29.32262 -18.75319 1.000 11.35293 ? 2   VAL C CG1 1 
ATOM   2322 C CG2 . VAL C 1 2   ? 6.63857   31.40709 -19.86294 1.000 10.29497 ? 2   VAL C CG2 1 
ATOM   2323 N N   . TYR C 1 3   ? 10.60681  28.91786 -19.84866 1.000 8.03083  ? 3   TYR C N   1 
ATOM   2324 C CA  . TYR C 1 3   ? 11.36407  27.68370 -19.70172 1.000 7.13421  ? 3   TYR C CA  1 
ATOM   2325 C C   . TYR C 1 3   ? 11.04652  27.11567 -18.32558 1.000 8.97219  ? 3   TYR C C   1 
ATOM   2326 O O   . TYR C 1 3   ? 11.47708  27.67048 -17.30596 1.000 9.84377  ? 3   TYR C O   1 
ATOM   2327 C CB  . TYR C 1 3   ? 12.86242  27.94685 -19.84580 1.000 8.42645  ? 3   TYR C CB  1 
ATOM   2328 C CG  . TYR C 1 3   ? 13.28992  28.19545 -21.25955 1.000 8.02310  ? 3   TYR C CG  1 
ATOM   2329 C CD1 . TYR C 1 3   ? 13.52842  27.13754 -22.12036 1.000 11.26390 ? 3   TYR C CD1 1 
ATOM   2330 C CD2 . TYR C 1 3   ? 13.47890  29.48355 -21.73556 1.000 7.32544  ? 3   TYR C CD2 1 
ATOM   2331 C CE1 . TYR C 1 3   ? 13.92015  27.34968 -23.41059 1.000 10.14426 ? 3   TYR C CE1 1 
ATOM   2332 C CE2 . TYR C 1 3   ? 13.88946  29.70631 -23.03693 1.000 9.60872  ? 3   TYR C CE2 1 
ATOM   2333 C CZ  . TYR C 1 3   ? 14.10358  28.62673 -23.86725 1.000 9.90818  ? 3   TYR C CZ  1 
ATOM   2334 O OH  . TYR C 1 3   ? 14.51878  28.81478 -25.16105 1.000 12.31059 ? 3   TYR C OH  1 
ATOM   2335 N N   . MET C 1 4   ? 10.28149  26.02816 -18.29421 1.000 7.47293  ? 4   MET C N   1 
ATOM   2336 C CA  . MET C 1 4   ? 10.06142  25.29690 -17.04774 1.000 8.49439  ? 4   MET C CA  1 
ATOM   2337 C C   . MET C 1 4   ? 11.23262  24.35429 -16.83994 1.000 8.93152  ? 4   MET C C   1 
ATOM   2338 O O   . MET C 1 4   ? 11.52484  23.52252 -17.70457 1.000 10.34629 ? 4   MET C O   1 
ATOM   2339 C CB  . MET C 1 4   ? 8.74705   24.50754 -17.08692 1.000 9.63668  ? 4   MET C CB  1 
ATOM   2340 C CG  . MET C 1 4   ? 7.49861   25.28015 -17.53963 1.000 11.47836 ? 4   MET C CG  1 
ATOM   2341 S SD  . MET C 1 4   ? 7.15461   26.67927 -16.45541 1.000 9.92217  ? 4   MET C SD  1 
ATOM   2342 C CE  . MET C 1 4   ? 6.83100   25.82091 -14.92190 1.000 11.13825 ? 4   MET C CE  1 
ATOM   2343 N N   . VAL C 1 5   ? 11.91827  24.47799 -15.71217 1.000 8.77615  ? 5   VAL C N   1 
ATOM   2344 C CA  . VAL C 1 5   ? 13.15055  23.72224 -15.48853 1.000 7.83223  ? 5   VAL C CA  1 
ATOM   2345 C C   . VAL C 1 5   ? 12.92534  22.82373 -14.28509 1.000 8.54499  ? 5   VAL C C   1 
ATOM   2346 O O   . VAL C 1 5   ? 12.82533  23.31222 -13.15083 1.000 10.58874 ? 5   VAL C O   1 
ATOM   2347 C CB  . VAL C 1 5   ? 14.34835  24.64982 -15.28181 1.000 7.76816  ? 5   VAL C CB  1 
ATOM   2348 C CG1 . VAL C 1 5   ? 15.62609  23.82238 -15.08717 1.000 11.10133 ? 5   VAL C CG1 1 
ATOM   2349 C CG2 . VAL C 1 5   ? 14.48161  25.58607 -16.47084 1.000 11.20909 ? 5   VAL C CG2 1 
ATOM   2350 N N   . TYR C 1 6   ? 12.83768  21.50919 -14.52670 1.000 7.40732  ? 6   TYR C N   1 
ATOM   2351 C CA  . TYR C 1 6   ? 12.50923  20.53762 -13.48009 1.000 10.05112 ? 6   TYR C CA  1 
ATOM   2352 C C   . TYR C 1 6   ? 13.79349  19.95128 -12.91426 1.000 10.88651 ? 6   TYR C C   1 
ATOM   2353 O O   . TYR C 1 6   ? 14.53089  19.26729 -13.62930 1.000 11.86049 ? 6   TYR C O   1 
ATOM   2354 C CB  . TYR C 1 6   ? 11.59827  19.44350 -14.02467 1.000 10.06823 ? 6   TYR C CB  1 
ATOM   2355 C CG  . TYR C 1 6   ? 10.32355  20.02534 -14.59223 1.000 7.90585  ? 6   TYR C CG  1 
ATOM   2356 C CD1 . TYR C 1 6   ? 9.23802   20.28309 -13.77061 1.000 8.65951  ? 6   TYR C CD1 1 
ATOM   2357 C CD2 . TYR C 1 6   ? 10.24125  20.37686 -15.93282 1.000 7.89896  ? 6   TYR C CD2 1 
ATOM   2358 C CE1 . TYR C 1 6   ? 8.06498   20.84255 -14.28023 1.000 8.54538  ? 6   TYR C CE1 1 
ATOM   2359 C CE2 . TYR C 1 6   ? 9.07068   20.94016 -16.45349 1.000 8.67713  ? 6   TYR C CE2 1 
ATOM   2360 C CZ  . TYR C 1 6   ? 7.99646   21.16720 -15.61716 1.000 8.57306  ? 6   TYR C CZ  1 
ATOM   2361 O OH  . TYR C 1 6   ? 6.82525   21.72173 -16.09925 1.000 10.19692 ? 6   TYR C OH  1 
ATOM   2362 N N   . VAL C 1 7   ? 14.06079  20.23788 -11.63150 1.000 9.74106  ? 7   VAL C N   1 
ATOM   2363 C CA  . VAL C 1 7   ? 15.28539  19.81714 -10.95503 1.000 10.02523 ? 7   VAL C CA  1 
ATOM   2364 C C   . VAL C 1 7   ? 14.92774  19.26849 -9.58129  1.000 11.74281 ? 7   VAL C C   1 
ATOM   2365 O O   . VAL C 1 7   ? 13.82658  19.47028 -9.07473  1.000 11.06033 ? 7   VAL C O   1 
ATOM   2366 C CB  . VAL C 1 7   ? 16.29236  20.97067 -10.81428 1.000 10.20498 ? 7   VAL C CB  1 
ATOM   2367 C CG1 . VAL C 1 7   ? 16.82717  21.37504 -12.18253 1.000 14.56345 ? 7   VAL C CG1 1 
ATOM   2368 C CG2 . VAL C 1 7   ? 15.62252  22.16344 -10.12706 1.000 10.88909 ? 7   VAL C CG2 1 
ATOM   2369 N N   . SER C 1 8   ? 15.87410  18.55642 -8.97869  1.000 10.57417 ? 8   SER C N   1 
ATOM   2370 C CA  . SER C 1 8   ? 15.64651  18.04636 -7.63618  1.000 12.28945 ? 8   SER C CA  1 
ATOM   2371 C C   . SER C 1 8   ? 15.91750  19.12176 -6.58995  1.000 13.84556 ? 8   SER C C   1 
ATOM   2372 O O   . SER C 1 8   ? 16.77062  19.99673 -6.76434  1.000 12.21023 ? 8   SER C O   1 
ATOM   2373 C CB  . SER C 1 8   ? 16.51645  16.81426 -7.36750  1.000 12.34078 ? 8   SER C CB  1 
ATOM   2374 O OG  . SER C 1 8   ? 16.09597  15.73058 -8.17547  1.000 15.19334 ? 8   SER C OG  1 
ATOM   2375 N N   . GLN C 1 9   ? 15.14889  19.06252 -5.50620  1.000 10.86011 ? 9   GLN C N   1 
ATOM   2376 C CA  . GLN C 1 9   ? 15.29939  20.02897 -4.43396  1.000 16.34393 ? 9   GLN C CA  1 
ATOM   2377 C C   . GLN C 1 9   ? 16.73773  20.04737 -3.93931  1.000 16.83821 ? 9   GLN C C   1 
ATOM   2378 O O   . GLN C 1 9   ? 17.34349  18.99375 -3.71824  1.000 14.72085 ? 9   GLN C O   1 
ATOM   2379 C CB  . GLN C 1 9   ? 14.34563  19.69492 -3.29317  1.000 19.52503 ? 9   GLN C CB  1 
ATOM   2380 C CG  . GLN C 1 9   ? 14.39653  20.67845 -2.13822  1.000 20.82712 ? 9   GLN C CG  1 
ATOM   2381 C CD  . GLN C 1 9   ? 13.25057  20.48778 -1.17695  1.000 34.72176 ? 9   GLN C CD  1 
ATOM   2382 O OE1 . GLN C 1 9   ? 12.39064  19.62754 -1.38042  1.000 32.91102 ? 9   GLN C OE1 1 
ATOM   2383 N NE2 . GLN C 1 9   ? 13.23513  21.28221 -0.10887  1.000 35.83523 ? 9   GLN C NE2 1 
ATOM   2384 N N   . ASP C 1 10  ? 17.28987  21.25148 -3.80859  1.000 17.20125 ? 10  ASP C N   1 
ATOM   2385 C CA  . ASP C 1 10  ? 18.61399  21.51909 -3.26362  1.000 17.44206 ? 10  ASP C CA  1 
ATOM   2386 C C   . ASP C 1 10  ? 19.74622  21.08074 -4.18861  1.000 19.17959 ? 10  ASP C C   1 
ATOM   2387 O O   . ASP C 1 10  ? 20.91031  21.22887 -3.82210  1.000 20.68814 ? 10  ASP C O   1 
ATOM   2388 C CB  . ASP C 1 10  ? 18.79544  20.86549 -1.88093  1.000 17.09012 ? 10  ASP C CB  1 
ATOM   2389 C CG  . ASP C 1 10  ? 17.87979  21.47268 -0.82038  1.000 21.42747 ? 10  ASP C CG  1 
ATOM   2390 O OD1 . ASP C 1 10  ? 17.41794  22.62084 -0.99403  1.000 26.48789 ? 10  ASP C OD1 1 
ATOM   2391 O OD2 . ASP C 1 10  ? 17.56083  20.76972 0.15495   1.000 22.47602 ? 10  ASP C OD2 1 
ATOM   2392 N N   . ARG C 1 11  ? 19.45851  20.54272 -5.37387  1.000 14.61481 ? 11  ARG C N   1 
ATOM   2393 C CA  . ARG C 1 11  ? 20.55186  20.18679 -6.27482  1.000 16.16488 ? 11  ARG C CA  1 
ATOM   2394 C C   . ARG C 1 11  ? 21.29661  21.42865 -6.74939  1.000 19.03764 ? 11  ARG C C   1 
ATOM   2395 O O   . ARG C 1 11  ? 22.52609  21.40246 -6.89759  1.000 20.50230 ? 11  ARG C O   1 
ATOM   2396 C CB  . ARG C 1 11  ? 20.02763  19.39543 -7.47473  1.000 15.50430 ? 11  ARG C CB  1 
ATOM   2397 C CG  . ARG C 1 11  ? 21.13122  18.91696 -8.43226  1.000 17.97777 ? 11  ARG C CG  1 
ATOM   2398 C CD  . ARG C 1 11  ? 22.00448  17.88096 -7.74543  1.000 17.67119 ? 11  ARG C CD  1 
ATOM   2399 N NE  . ARG C 1 11  ? 23.18683  17.51433 -8.51699  1.000 22.63641 ? 11  ARG C NE  1 
ATOM   2400 C CZ  . ARG C 1 11  ? 24.26837  18.26855 -8.65277  1.000 24.48176 ? 11  ARG C CZ  1 
ATOM   2401 N NH1 . ARG C 1 11  ? 24.34619  19.47539 -8.11153  1.000 21.06612 ? 11  ARG C NH1 1 
ATOM   2402 N NH2 . ARG C 1 11  ? 25.30676  17.79368 -9.33735  1.000 28.22332 ? 11  ARG C NH2 1 
ATOM   2403 N N   . LEU C 1 12  ? 20.56727  22.51684 -6.99651  1.000 16.20759 ? 12  LEU C N   1 
ATOM   2404 C CA  . LEU C 1 12  ? 21.13047  23.78776 -7.43453  1.000 19.63676 ? 12  LEU C CA  1 
ATOM   2405 C C   . LEU C 1 12  ? 21.11173  24.78607 -6.28687  1.000 17.02254 ? 12  LEU C C   1 
ATOM   2406 O O   . LEU C 1 12  ? 20.04299  25.10230 -5.74451  1.000 15.06209 ? 12  LEU C O   1 
ATOM   2407 C CB  . LEU C 1 12  ? 20.35243  24.36197 -8.61741  1.000 16.48493 ? 12  LEU C CB  1 
ATOM   2408 C CG  . LEU C 1 12  ? 20.29744  23.47538 -9.84219  1.000 16.82797 ? 12  LEU C CG  1 
ATOM   2409 C CD1 . LEU C 1 12  ? 19.51692  24.20058 -10.93124 1.000 17.89440 ? 12  LEU C CD1 1 
ATOM   2410 C CD2 . LEU C 1 12  ? 21.70323  23.14396 -10.28713 1.000 17.54623 ? 12  LEU C CD2 1 
ATOM   2411 N N   . THR C 1 13  ? 22.29170  25.31247 -5.94572  1.000 18.48067 ? 13  THR C N   1 
ATOM   2412 C CA  . THR C 1 13  ? 22.35756  26.44152 -5.03938  1.000 20.91360 ? 13  THR C CA  1 
ATOM   2413 C C   . THR C 1 13  ? 21.63929  27.63615 -5.66268  1.000 22.59110 ? 13  THR C C   1 
ATOM   2414 O O   . THR C 1 13  ? 21.38358  27.65021 -6.87007  1.000 17.66371 ? 13  THR C O   1 
ATOM   2415 C CB  . THR C 1 13  ? 23.81040  26.80821 -4.75322  1.000 20.79147 ? 13  THR C CB  1 
ATOM   2416 O OG1 . THR C 1 13  ? 24.46043  27.17227 -5.97714  1.000 23.02586 ? 13  THR C OG1 1 
ATOM   2417 C CG2 . THR C 1 13  ? 24.55733  25.62242 -4.13900  1.000 21.68936 ? 13  THR C CG2 1 
ATOM   2418 N N   . PRO C 1 14  ? 21.30600  28.66032 -4.86573  1.000 21.19186 ? 14  PRO C N   1 
ATOM   2419 C CA  . PRO C 1 14  ? 20.77182  29.88642 -5.47613  1.000 20.62481 ? 14  PRO C CA  1 
ATOM   2420 C C   . PRO C 1 14  ? 21.68610  30.47799 -6.53362  1.000 21.16743 ? 14  PRO C C   1 
ATOM   2421 O O   . PRO C 1 14  ? 21.20562  30.94827 -7.57217  1.000 19.26349 ? 14  PRO C O   1 
ATOM   2422 C CB  . PRO C 1 14  ? 20.58163  30.81625 -4.27061  1.000 25.22993 ? 14  PRO C CB  1 
ATOM   2423 C CG  . PRO C 1 14  ? 20.32554  29.88426 -3.14147  1.000 23.07881 ? 14  PRO C CG  1 
ATOM   2424 C CD  . PRO C 1 14  ? 21.15281  28.66726 -3.39619  1.000 23.21964 ? 14  PRO C CD  1 
ATOM   2425 N N   . SER C 1 15  ? 22.99857  30.44398 -6.32271  1.000 22.54244 ? 15  SER C N   1 
ATOM   2426 C CA  . SER C 1 15  ? 23.88996  30.96254 -7.35074  1.000 18.64683 ? 15  SER C CA  1 
ATOM   2427 C C   . SER C 1 15  ? 23.89810  30.06381 -8.58780  1.000 18.12697 ? 15  SER C C   1 
ATOM   2428 O O   . SER C 1 15  ? 24.00359  30.56881 -9.71194  1.000 19.42977 ? 15  SER C O   1 
ATOM   2429 C CB  . SER C 1 15  ? 25.29671  31.16214 -6.77322  1.000 26.14553 ? 15  SER C CB  1 
ATOM   2430 O OG  . SER C 1 15  ? 26.16356  30.10319 -7.11207  1.000 33.65787 ? 15  SER C OG  1 
ATOM   2431 N N   . ALA C 1 16  ? 23.74395  28.74762 -8.41872  1.000 18.16065 ? 16  ALA C N   1 
ATOM   2432 C CA  . ALA C 1 16  ? 23.68134  27.87919 -9.59178  1.000 16.01867 ? 16  ALA C CA  1 
ATOM   2433 C C   . ALA C 1 16  ? 22.36244  28.05556 -10.33310 1.000 18.27500 ? 16  ALA C C   1 
ATOM   2434 O O   . ALA C 1 16  ? 22.32322  27.97779 -11.56812 1.000 16.21085 ? 16  ALA C O   1 
ATOM   2435 C CB  . ALA C 1 16  ? 23.87409  26.41955 -9.19389  1.000 17.05581 ? 16  ALA C CB  1 
ATOM   2436 N N   . LYS C 1 17  ? 21.26882  28.25818 -9.59628  1.000 16.80155 ? 17  LYS C N   1 
ATOM   2437 C CA  . LYS C 1 17  ? 20.00302  28.58414 -10.25166 1.000 13.87561 ? 17  LYS C CA  1 
ATOM   2438 C C   . LYS C 1 17  ? 20.14910  29.85956 -11.06485 1.000 17.12034 ? 17  LYS C C   1 
ATOM   2439 O O   . LYS C 1 17  ? 19.66120  29.95777 -12.19482 1.000 14.26122 ? 17  LYS C O   1 
ATOM   2440 C CB  . LYS C 1 17  ? 18.89051  28.73760 -9.20838  1.000 15.05737 ? 17  LYS C CB  1 
ATOM   2441 C CG  . LYS C 1 17  ? 18.22175  27.44280 -8.78956  1.000 17.17786 ? 17  LYS C CG  1 
ATOM   2442 C CD  . LYS C 1 17  ? 17.06991  27.73782 -7.83993  1.000 17.96022 ? 17  LYS C CD  1 
ATOM   2443 C CE  . LYS C 1 17  ? 16.69355  26.49422 -7.04833  1.000 20.84703 ? 17  LYS C CE  1 
ATOM   2444 N NZ  . LYS C 1 17  ? 15.99719  26.89487 -5.80097  1.000 28.03623 ? 17  LYS C NZ  1 
ATOM   2445 N N   . HIS C 1 18  ? 20.83762  30.85141 -10.51155 1.000 15.49056 ? 18  HIS C N   1 
ATOM   2446 C CA  . HIS C 1 18  ? 20.98667  32.10368 -11.23109 1.000 16.29666 ? 18  HIS C CA  1 
ATOM   2447 C C   . HIS C 1 18  ? 21.83214  31.90091 -12.48007 1.000 17.18530 ? 18  HIS C C   1 
ATOM   2448 O O   . HIS C 1 18  ? 21.50399  32.42439 -13.55062 1.000 16.25311 ? 18  HIS C O   1 
ATOM   2449 C CB  . HIS C 1 18  ? 21.59047  33.14761 -10.28894 1.000 16.63771 ? 18  HIS C CB  1 
ATOM   2450 C CG  . HIS C 1 18  ? 21.75174  34.50637 -10.89492 1.000 22.38703 ? 18  HIS C CG  1 
ATOM   2451 N ND1 . HIS C 1 18  ? 22.77717  35.35794 -10.54493 1.000 31.16628 ? 18  HIS C ND1 1 
ATOM   2452 C CD2 . HIS C 1 18  ? 21.00221  35.17408 -11.80307 1.000 21.45543 ? 18  HIS C CD2 1 
ATOM   2453 C CE1 . HIS C 1 18  ? 22.65609  36.48843 -11.21778 1.000 34.67946 ? 18  HIS C CE1 1 
ATOM   2454 N NE2 . HIS C 1 18  ? 21.58847  36.40088 -11.99104 1.000 28.46125 ? 18  HIS C NE2 1 
ATOM   2455 N N   . ALA C 1 19  ? 22.89130  31.09301 -12.37184 1.000 14.28466 ? 19  ALA C N   1 
ATOM   2456 C CA  . ALA C 1 19  ? 23.73933  30.81457 -13.52245 1.000 15.10123 ? 19  ALA C CA  1 
ATOM   2457 C C   . ALA C 1 19  ? 22.98471  30.02602 -14.58324 1.000 13.19869 ? 19  ALA C C   1 
ATOM   2458 O O   . ALA C 1 19  ? 23.13874  30.29168 -15.78255 1.000 16.02395 ? 19  ALA C O   1 
ATOM   2459 C CB  . ALA C 1 19  ? 24.99300  30.05691 -13.07990 1.000 18.00664 ? 19  ALA C CB  1 
ATOM   2460 N N   . VAL C 1 20  ? 22.16239  29.05937 -14.16795 1.000 12.95292 ? 20  VAL C N   1 
ATOM   2461 C CA  . VAL C 1 20  ? 21.38257  28.30218 -15.15008 1.000 12.86561 ? 20  VAL C CA  1 
ATOM   2462 C C   . VAL C 1 20  ? 20.36153  29.20743 -15.83096 1.000 11.38606 ? 20  VAL C C   1 
ATOM   2463 O O   . VAL C 1 20  ? 20.19461  29.16838 -17.05785 1.000 13.31849 ? 20  VAL C O   1 
ATOM   2464 C CB  . VAL C 1 20  ? 20.71175  27.08918 -14.48173 1.000 10.36506 ? 20  VAL C CB  1 
ATOM   2465 C CG1 . VAL C 1 20  ? 19.62954  26.47728 -15.40161 1.000 13.20380 ? 20  VAL C CG1 1 
ATOM   2466 C CG2 . VAL C 1 20  ? 21.74809  26.03768 -14.13999 1.000 11.97163 ? 20  VAL C CG2 1 
ATOM   2467 N N   . ALA C 1 21  ? 19.67481  30.04435 -15.05347 1.000 11.81493 ? 21  ALA C N   1 
ATOM   2468 C CA  . ALA C 1 21  ? 18.73723  30.99597 -15.64946 1.000 14.01908 ? 21  ALA C CA  1 
ATOM   2469 C C   . ALA C 1 21  ? 19.43672  31.90668 -16.65082 1.000 13.33309 ? 21  ALA C C   1 
ATOM   2470 O O   . ALA C 1 21  ? 18.92989  32.13211 -17.75956 1.000 14.88146 ? 21  ALA C O   1 
ATOM   2471 C CB  . ALA C 1 21  ? 18.06200  31.82238 -14.54919 1.000 13.15466 ? 21  ALA C CB  1 
ATOM   2472 N N   . LYS C 1 22  ? 20.61670  32.42855 -16.28053 1.000 13.79759 ? 22  LYS C N   1 
ATOM   2473 C CA  . LYS C 1 22  ? 21.37799  33.28190 -17.18798 1.000 14.81388 ? 22  LYS C CA  1 
ATOM   2474 C C   . LYS C 1 22  ? 21.79058  32.52835 -18.44845 1.000 13.18368 ? 22  LYS C C   1 
ATOM   2475 O O   . LYS C 1 22  ? 21.73693  33.07623 -19.55769 1.000 17.48959 ? 22  LYS C O   1 
ATOM   2476 C CB  . LYS C 1 22  ? 22.61018  33.82373 -16.46364 1.000 17.03358 ? 22  LYS C CB  1 
ATOM   2477 C CG  . LYS C 1 22  ? 23.53333  34.65373 -17.33385 1.000 27.59334 ? 22  LYS C CG  1 
ATOM   2478 C CD  . LYS C 1 22  ? 24.55118  35.42949 -16.49766 1.000 28.54686 ? 22  LYS C CD  1 
ATOM   2479 C CE  . LYS C 1 22  ? 25.79946  35.71368 -17.31608 1.000 37.64189 ? 22  LYS C CE  1 
ATOM   2480 N NZ  . LYS C 1 22  ? 25.54865  36.76223 -18.34592 1.000 34.89629 ? 22  LYS C NZ  1 
ATOM   2481 N N   . ALA C 1 23  ? 22.20571  31.27004 -18.29955 1.000 13.62252 ? 23  ALA C N   1 
ATOM   2482 C CA  . ALA C 1 23  ? 22.63884  30.48493 -19.44879 1.000 12.21644 ? 23  ALA C CA  1 
ATOM   2483 C C   . ALA C 1 23  ? 21.50051  30.28610 -20.43943 1.000 12.53218 ? 23  ALA C C   1 
ATOM   2484 O O   . ALA C 1 23  ? 21.68981  30.42322 -21.65279 1.000 14.46706 ? 23  ALA C O   1 
ATOM   2485 C CB  . ALA C 1 23  ? 23.18038  29.13823 -18.98538 1.000 16.97015 ? 23  ALA C CB  1 
ATOM   2486 N N   . ILE C 1 24  ? 20.30250  29.98840 -19.93679 1.000 12.61032 ? 24  ILE C N   1 
ATOM   2487 C CA  . ILE C 1 24  ? 19.16228  29.81030 -20.83414 1.000 11.89725 ? 24  ILE C CA  1 
ATOM   2488 C C   . ILE C 1 24  ? 18.76405  31.13819 -21.45790 1.000 14.73319 ? 24  ILE C C   1 
ATOM   2489 O O   . ILE C 1 24  ? 18.47455  31.21851 -22.66193 1.000 12.68280 ? 24  ILE C O   1 
ATOM   2490 C CB  . ILE C 1 24  ? 17.99611  29.17364 -20.06127 1.000 10.15664 ? 24  ILE C CB  1 
ATOM   2491 C CG1 . ILE C 1 24  ? 18.35089  27.74120 -19.66286 1.000 10.97231 ? 24  ILE C CG1 1 
ATOM   2492 C CG2 . ILE C 1 24  ? 16.68608  29.24762 -20.87507 1.000 11.31827 ? 24  ILE C CG2 1 
ATOM   2493 C CD1 . ILE C 1 24  ? 17.34833  27.11149 -18.68964 1.000 8.82379  ? 24  ILE C CD1 1 
ATOM   2494 N N   . THR C 1 25  ? 18.71013  32.19433 -20.64211 1.000 11.12675 ? 25  THR C N   1 
ATOM   2495 C CA  . THR C 1 25  ? 18.30830  33.51034 -21.12486 1.000 12.42802 ? 25  THR C CA  1 
ATOM   2496 C C   . THR C 1 25  ? 19.24766  34.01226 -22.21174 1.000 14.34351 ? 25  THR C C   1 
ATOM   2497 O O   . THR C 1 25  ? 18.80326  34.44666 -23.27983 1.000 16.74756 ? 25  THR C O   1 
ATOM   2498 C CB  . THR C 1 25  ? 18.26722  34.48648 -19.95419 1.000 14.38612 ? 25  THR C CB  1 
ATOM   2499 O OG1 . THR C 1 25  ? 17.33046  34.00010 -18.97708 1.000 14.81572 ? 25  THR C OG1 1 
ATOM   2500 C CG2 . THR C 1 25  ? 17.88082  35.87355 -20.44005 1.000 13.67989 ? 25  THR C CG2 1 
ATOM   2501 N N   . ASP C 1 26  ? 20.56080  33.94572 -21.95975 1.000 13.26618 ? 26  ASP C N   1 
ATOM   2502 C CA  . ASP C 1 26  ? 21.52924  34.41699 -22.94326 1.000 14.61173 ? 26  ASP C CA  1 
ATOM   2503 C C   . ASP C 1 26  ? 21.44689  33.60706 -24.22627 1.000 10.57950 ? 26  ASP C C   1 
ATOM   2504 O O   . ASP C 1 26  ? 21.61100  34.15402 -25.32416 1.000 13.64240 ? 26  ASP C O   1 
ATOM   2505 C CB  . ASP C 1 26  ? 22.94838  34.33048 -22.36986 1.000 13.89044 ? 26  ASP C CB  1 
ATOM   2506 C CG  . ASP C 1 26  ? 23.22032  35.35758 -21.28410 1.000 19.04235 ? 26  ASP C CG  1 
ATOM   2507 O OD1 . ASP C 1 26  ? 22.40365  36.28244 -21.06757 1.000 22.23811 ? 26  ASP C OD1 1 
ATOM   2508 O OD2 . ASP C 1 26  ? 24.27670  35.21929 -20.63249 1.000 24.91216 ? 26  ASP C OD2 1 
ATOM   2509 N N   . ALA C 1 27  ? 21.18449  32.30437 -24.10873 1.000 12.07045 ? 27  ALA C N   1 
ATOM   2510 C CA  . ALA C 1 27  ? 21.07758  31.47071 -25.29849 1.000 12.15458 ? 27  ALA C CA  1 
ATOM   2511 C C   . ALA C 1 27  ? 19.86826  31.86945 -26.12454 1.000 12.35118 ? 27  ALA C C   1 
ATOM   2512 O O   . ALA C 1 27  ? 19.95325  31.97087 -27.35464 1.000 13.80306 ? 27  ALA C O   1 
ATOM   2513 C CB  . ALA C 1 27  ? 21.00823  29.99387 -24.90774 1.000 14.36091 ? 27  ALA C CB  1 
ATOM   2514 N N   . HIS C 1 28  ? 18.73793  32.11015 -25.46058 1.000 13.24998 ? 28  HIS C N   1 
ATOM   2515 C CA  . HIS C 1 28  ? 17.52455  32.48434 -26.17704 1.000 11.38122 ? 28  HIS C CA  1 
ATOM   2516 C C   . HIS C 1 28  ? 17.67737  33.84817 -26.83650 1.000 12.57875 ? 28  HIS C C   1 
ATOM   2517 O O   . HIS C 1 28  ? 17.37921  34.01116 -28.02710 1.000 13.05835 ? 28  HIS C O   1 
ATOM   2518 C CB  . HIS C 1 28  ? 16.32992  32.47453 -25.22868 1.000 12.30903 ? 28  HIS C CB  1 
ATOM   2519 C CG  . HIS C 1 28  ? 15.01874  32.44698 -25.94243 1.000 10.40194 ? 28  HIS C CG  1 
ATOM   2520 N ND1 . HIS C 1 28  ? 14.37392  31.26489 -26.24526 1.000 11.21793 ? 28  HIS C ND1 1 
ATOM   2521 C CD2 . HIS C 1 28  ? 14.25412  33.44035 -26.44978 1.000 13.52282 ? 28  HIS C CD2 1 
ATOM   2522 C CE1 . HIS C 1 28  ? 13.25631  31.53495 -26.89805 1.000 12.41515 ? 28  HIS C CE1 1 
ATOM   2523 N NE2 . HIS C 1 28  ? 13.16109  32.84581 -27.03664 1.000 14.24077 ? 28  HIS C NE2 1 
ATOM   2524 N N   . ARG C 1 29  ? 18.13310  34.84709 -26.07830 1.000 12.69069 ? 29  ARG C N   1 
ATOM   2525 C CA  . ARG C 1 29  ? 18.37634  36.16060 -26.66851 1.000 13.54959 ? 29  ARG C CA  1 
ATOM   2526 C C   . ARG C 1 29  ? 19.39920  36.07542 -27.79660 1.000 14.77105 ? 29  ARG C C   1 
ATOM   2527 O O   . ARG C 1 29  ? 19.20050  36.64961 -28.87333 1.000 18.44013 ? 29  ARG C O   1 
ATOM   2528 C CB  . ARG C 1 29  ? 18.84635  37.14882 -25.60332 1.000 18.21533 ? 29  ARG C CB  1 
ATOM   2529 C CG  . ARG C 1 29  ? 19.60020  38.33939 -26.22670 1.000 24.28249 ? 29  ARG C CG  1 
ATOM   2530 C CD  . ARG C 1 29  ? 19.29788  39.66416 -25.55671 1.000 29.63497 ? 29  ARG C CD  1 
ATOM   2531 N NE  . ARG C 1 29  ? 19.24678  40.74915 -26.53360 1.000 35.17477 ? 29  ARG C NE  1 
ATOM   2532 C CZ  . ARG C 1 29  ? 18.56353  41.87850 -26.38424 1.000 38.88309 ? 29  ARG C CZ  1 
ATOM   2533 N NH1 . ARG C 1 29  ? 17.90655  42.15130 -25.26804 1.000 39.18434 ? 29  ARG C NH1 1 
ATOM   2534 N NH2 . ARG C 1 29  ? 18.53432  42.75527 -27.38323 1.000 43.25389 ? 29  ARG C NH2 1 
ATOM   2535 N N   . GLY C 1 30  ? 20.49399  35.34594 -27.56733 1.000 15.81696 ? 30  GLY C N   1 
ATOM   2536 C CA  . GLY C 1 30  ? 21.55805  35.27820 -28.55826 1.000 16.85739 ? 30  GLY C CA  1 
ATOM   2537 C C   . GLY C 1 30  ? 21.09998  34.74105 -29.90107 1.000 18.88460 ? 30  GLY C C   1 
ATOM   2538 O O   . GLY C 1 30  ? 21.50625  35.24222 -30.95413 1.000 18.89508 ? 30  GLY C O   1 
ATOM   2539 N N   . LEU C 1 31  ? 20.24644  33.71788 -29.88825 1.000 12.93495 ? 31  LEU C N   1 
ATOM   2540 C CA  . LEU C 1 31  ? 19.86180  33.04158 -31.11484 1.000 15.41996 ? 31  LEU C CA  1 
ATOM   2541 C C   . LEU C 1 31  ? 18.55960  33.55110 -31.71845 1.000 18.64067 ? 31  LEU C C   1 
ATOM   2542 O O   . LEU C 1 31  ? 18.36314  33.39219 -32.92720 1.000 17.36693 ? 31  LEU C O   1 
ATOM   2543 C CB  . LEU C 1 31  ? 19.75846  31.53449 -30.86840 1.000 16.49451 ? 31  LEU C CB  1 
ATOM   2544 C CG  . LEU C 1 31  ? 21.13634  30.87513 -30.72866 1.000 15.88833 ? 31  LEU C CG  1 
ATOM   2545 C CD1 . LEU C 1 31  ? 21.02735  29.49683 -30.11407 1.000 17.35873 ? 31  LEU C CD1 1 
ATOM   2546 C CD2 . LEU C 1 31  ? 21.82740  30.79574 -32.09017 1.000 20.91225 ? 31  LEU C CD2 1 
ATOM   2547 N N   . THR C 1 32  ? 17.67261  34.16379 -30.92300 1.000 16.36929 ? 32  THR C N   1 
ATOM   2548 C CA  . THR C 1 32  ? 16.38815  34.63858 -31.43008 1.000 14.90870 ? 32  THR C CA  1 
ATOM   2549 C C   . THR C 1 32  ? 16.26357  36.15162 -31.50198 1.000 19.09016 ? 32  THR C C   1 
ATOM   2550 O O   . THR C 1 32  ? 15.37774  36.64171 -32.20753 1.000 21.28150 ? 32  THR C O   1 
ATOM   2551 C CB  . THR C 1 32  ? 15.22385  34.12218 -30.56939 1.000 15.56478 ? 32  THR C CB  1 
ATOM   2552 O OG1 . THR C 1 32  ? 15.25595  34.76361 -29.28534 1.000 15.85361 ? 32  THR C OG1 1 
ATOM   2553 C CG2 . THR C 1 32  ? 15.27442  32.60095 -30.40148 1.000 15.48936 ? 32  THR C CG2 1 
ATOM   2554 N N   . GLY C 1 33  ? 17.09530  36.90082 -30.78157 1.000 16.40638 ? 33  GLY C N   1 
ATOM   2555 C CA  . GLY C 1 33  ? 16.97312  38.34369 -30.73182 1.000 18.74467 ? 33  GLY C CA  1 
ATOM   2556 C C   . GLY C 1 33  ? 15.92948  38.88199 -29.77256 1.000 21.30387 ? 33  GLY C C   1 
ATOM   2557 O O   . GLY C 1 33  ? 15.88364  40.10215 -29.55848 1.000 22.47873 ? 33  GLY C O   1 
ATOM   2558 N N   . THR C 1 34  ? 15.08794  38.02569 -29.19157 1.000 20.28020 ? 34  THR C N   1 
ATOM   2559 C CA  . THR C 1 34  ? 14.14684  38.47397 -28.17243 1.000 18.53975 ? 34  THR C CA  1 
ATOM   2560 C C   . THR C 1 34  ? 14.88626  39.14590 -27.01538 1.000 21.86203 ? 34  THR C C   1 
ATOM   2561 O O   . THR C 1 34  ? 16.01065  38.77769 -26.66645 1.000 24.66459 ? 34  THR C O   1 
ATOM   2562 C CB  . THR C 1 34  ? 13.30348  37.28696 -27.67891 1.000 20.45756 ? 34  THR C CB  1 
ATOM   2563 O OG1 . THR C 1 34  ? 12.77453  36.57137 -28.80406 1.000 21.11402 ? 34  THR C OG1 1 
ATOM   2564 C CG2 . THR C 1 34  ? 12.15609  37.73658 -26.78473 1.000 25.56874 ? 34  THR C CG2 1 
ATOM   2565 N N   . GLN C 1 35  ? 14.25336  40.15957 -26.42824 1.000 20.43172 ? 35  GLN C N   1 
ATOM   2566 C CA  . GLN C 1 35  ? 14.87248  40.89314 -25.32916 1.000 19.74567 ? 35  GLN C CA  1 
ATOM   2567 C C   . GLN C 1 35  ? 15.05422  39.99081 -24.11479 1.000 20.88356 ? 35  GLN C C   1 
ATOM   2568 O O   . GLN C 1 35  ? 14.28472  39.04874 -23.90388 1.000 18.34616 ? 35  GLN C O   1 
ATOM   2569 C CB  . GLN C 1 35  ? 14.00628  42.09307 -24.94697 1.000 19.75709 ? 35  GLN C CB  1 
ATOM   2570 C CG  . GLN C 1 35  ? 13.83975  43.12102 -26.07048 1.000 19.41167 ? 35  GLN C CG  1 
ATOM   2571 C CD  . GLN C 1 35  ? 12.47351  43.01082 -26.70346 1.000 21.78656 ? 35  GLN C CD  1 
ATOM   2572 O OE1 . GLN C 1 35  ? 11.95569  41.90211 -26.85486 1.000 20.04010 ? 35  GLN C OE1 1 
ATOM   2573 N NE2 . GLN C 1 35  ? 11.89715  44.14216 -27.11995 1.000 18.44431 ? 35  GLN C NE2 1 
ATOM   2574 N N   . HIS C 1 36  ? 16.08225  40.29907 -23.31050 1.000 19.95256 ? 36  HIS C N   1 
ATOM   2575 C CA  . HIS C 1 36  ? 16.34868  39.53688 -22.08987 1.000 19.17745 ? 36  HIS C CA  1 
ATOM   2576 C C   . HIS C 1 36  ? 15.07253  39.34169 -21.29031 1.000 14.98113 ? 36  HIS C C   1 
ATOM   2577 O O   . HIS C 1 36  ? 14.76586  38.23263 -20.83796 1.000 16.43463 ? 36  HIS C O   1 
ATOM   2578 C CB  . HIS C 1 36  ? 17.36010  40.25784 -21.18698 1.000 18.64055 ? 36  HIS C CB  1 
ATOM   2579 C CG  . HIS C 1 36  ? 18.76833  40.27206 -21.69311 1.000 32.16730 ? 36  HIS C CG  1 
ATOM   2580 N ND1 . HIS C 1 36  ? 19.19146  41.11446 -22.69894 1.000 35.09514 ? 36  HIS C ND1 1 
ATOM   2581 C CD2 . HIS C 1 36  ? 19.85707  39.55866 -21.31716 1.000 35.95063 ? 36  HIS C CD2 1 
ATOM   2582 C CE1 . HIS C 1 36  ? 20.48119  40.92138 -22.91876 1.000 37.33039 ? 36  HIS C CE1 1 
ATOM   2583 N NE2 . HIS C 1 36  ? 20.90575  39.97299 -22.10373 1.000 38.94340 ? 36  HIS C NE2 1 
ATOM   2584 N N   . PHE C 1 37  ? 14.31909  40.42697 -21.09674 1.000 15.18423 ? 37  PHE C N   1 
ATOM   2585 C CA  . PHE C 1 37  ? 13.25564  40.42613 -20.09965 1.000 14.20122 ? 37  PHE C CA  1 
ATOM   2586 C C   . PHE C 1 37  ? 12.07577  39.53928 -20.47795 1.000 12.44585 ? 37  PHE C C   1 
ATOM   2587 O O   . PHE C 1 37  ? 11.24121  39.26365 -19.60633 1.000 13.08630 ? 37  PHE C O   1 
ATOM   2588 C CB  . PHE C 1 37  ? 12.75759  41.85246 -19.82703 1.000 14.56485 ? 37  PHE C CB  1 
ATOM   2589 C CG  . PHE C 1 37  ? 12.48929  42.66818 -21.05782 1.000 15.56233 ? 37  PHE C CG  1 
ATOM   2590 C CD1 . PHE C 1 37  ? 11.35008  42.45574 -21.80961 1.000 15.85701 ? 37  PHE C CD1 1 
ATOM   2591 C CD2 . PHE C 1 37  ? 13.33737  43.70785 -21.41864 1.000 17.72176 ? 37  PHE C CD2 1 
ATOM   2592 C CE1 . PHE C 1 37  ? 11.08807  43.22516 -22.93154 1.000 16.01147 ? 37  PHE C CE1 1 
ATOM   2593 C CE2 . PHE C 1 37  ? 13.07833  44.48877 -22.53545 1.000 18.34565 ? 37  PHE C CE2 1 
ATOM   2594 C CZ  . PHE C 1 37  ? 11.95138  44.24984 -23.29223 1.000 18.29693 ? 37  PHE C CZ  1 
ATOM   2595 N N   . LEU C 1 38  ? 11.99067  39.08333 -21.73508 1.000 12.12610 ? 38  LEU C N   1 
ATOM   2596 C CA  . LEU C 1 38  ? 10.91419  38.17492 -22.10929 1.000 11.96675 ? 38  LEU C CA  1 
ATOM   2597 C C   . LEU C 1 38  ? 11.24344  36.72963 -21.76360 1.000 12.95460 ? 38  LEU C C   1 
ATOM   2598 O O   . LEU C 1 38  ? 10.36876  35.85843 -21.87244 1.000 13.45512 ? 38  LEU C O   1 
ATOM   2599 C CB  . LEU C 1 38  ? 10.61202  38.30523 -23.61168 1.000 14.95340 ? 38  LEU C CB  1 
ATOM   2600 C CG  . LEU C 1 38  ? 9.93209   39.61946 -24.02906 1.000 15.23283 ? 38  LEU C CG  1 
ATOM   2601 C CD1 . LEU C 1 38  ? 9.64864   39.68468 -25.52713 1.000 18.55199 ? 38  LEU C CD1 1 
ATOM   2602 C CD2 . LEU C 1 38  ? 8.64629   39.80611 -23.24259 1.000 15.04705 ? 38  LEU C CD2 1 
ATOM   2603 N N   . ALA C 1 39  ? 12.47437  36.44117 -21.35748 1.000 14.36076 ? 39  ALA C N   1 
ATOM   2604 C CA  . ALA C 1 39  ? 12.85752  35.06669 -21.05613 1.000 12.95993 ? 39  ALA C CA  1 
ATOM   2605 C C   . ALA C 1 39  ? 12.53914  34.78819 -19.59444 1.000 12.80188 ? 39  ALA C C   1 
ATOM   2606 O O   . ALA C 1 39  ? 13.17021  35.35038 -18.69131 1.000 13.16487 ? 39  ALA C O   1 
ATOM   2607 C CB  . ALA C 1 39  ? 14.33176  34.82782 -21.36884 1.000 14.03982 ? 39  ALA C CB  1 
ATOM   2608 N N   . GLN C 1 40  ? 11.54176  33.93257 -19.35638 1.000 11.03754 ? 40  GLN C N   1 
ATOM   2609 C CA  . GLN C 1 40  ? 11.19906  33.48861 -18.01856 1.000 9.92177  ? 40  GLN C CA  1 
ATOM   2610 C C   . GLN C 1 40  ? 11.77117  32.09379 -17.80946 1.000 10.56374 ? 40  GLN C C   1 
ATOM   2611 O O   . GLN C 1 40  ? 11.56270  31.20188 -18.63525 1.000 10.68192 ? 40  GLN C O   1 
ATOM   2612 C CB  . GLN C 1 40  ? 9.68138   33.46508 -17.79570 1.000 7.95566  ? 40  GLN C CB  1 
ATOM   2613 C CG  . GLN C 1 40  ? 9.31353   32.83600 -16.44726 1.000 10.44675 ? 40  GLN C CG  1 
ATOM   2614 C CD  . GLN C 1 40  ? 7.83101   32.85917 -16.09524 1.000 11.97043 ? 40  GLN C CD  1 
ATOM   2615 O OE1 . GLN C 1 40  ? 7.39494   32.07352 -15.25897 1.000 14.00193 ? 40  GLN C OE1 1 
ATOM   2616 N NE2 . GLN C 1 40  ? 7.06144   33.77528 -16.69518 1.000 10.71234 ? 40  GLN C NE2 1 
ATOM   2617 N N   . VAL C 1 41  ? 12.51249  31.92060 -16.72640 1.000 8.95180  ? 41  VAL C N   1 
ATOM   2618 C CA  . VAL C 1 41  ? 13.01980  30.61715 -16.31919 1.000 8.13195  ? 41  VAL C CA  1 
ATOM   2619 C C   . VAL C 1 41  ? 12.37620  30.32133 -14.97628 1.000 12.08127 ? 41  VAL C C   1 
ATOM   2620 O O   . VAL C 1 41  ? 12.54244  31.09095 -14.02736 1.000 12.76518 ? 41  VAL C O   1 
ATOM   2621 C CB  . VAL C 1 41  ? 14.55542  30.59513 -16.23427 1.000 8.69283  ? 41  VAL C CB  1 
ATOM   2622 C CG1 . VAL C 1 41  ? 15.03117  29.23038 -15.77312 1.000 9.58397  ? 41  VAL C CG1 1 
ATOM   2623 C CG2 . VAL C 1 41  ? 15.15188  30.91679 -17.61462 1.000 12.54949 ? 41  VAL C CG2 1 
ATOM   2624 N N   . ASN C 1 42  ? 11.61180  29.23549 -14.90854 1.000 8.81960  ? 42  ASN C N   1 
ATOM   2625 C CA  . ASN C 1 42  ? 10.74703  28.94589 -13.77156 1.000 8.37678  ? 42  ASN C CA  1 
ATOM   2626 C C   . ASN C 1 42  ? 11.17028  27.58625 -13.21813 1.000 9.32378  ? 42  ASN C C   1 
ATOM   2627 O O   . ASN C 1 42  ? 10.85082  26.54888 -13.79880 1.000 9.91399  ? 42  ASN C O   1 
ATOM   2628 C CB  . ASN C 1 42  ? 9.28654   28.98619 -14.22480 1.000 9.13241  ? 42  ASN C CB  1 
ATOM   2629 C CG  . ASN C 1 42  ? 8.31163   29.09735 -13.07549 1.000 12.39244 ? 42  ASN C CG  1 
ATOM   2630 O OD1 . ASN C 1 42  ? 8.43285   28.39430 -12.07523 1.000 14.62847 ? 42  ASN C OD1 1 
ATOM   2631 N ND2 . ASN C 1 42  ? 7.32690   29.97936 -13.21627 1.000 10.47123 ? 42  ASN C ND2 1 
ATOM   2632 N N   . PHE C 1 43  ? 11.91754  27.59290 -12.11334 1.000 9.67212  ? 43  PHE C N   1 
ATOM   2633 C CA  . PHE C 1 43  ? 12.45212  26.35780 -11.55175 1.000 9.58381  ? 43  PHE C CA  1 
ATOM   2634 C C   . PHE C 1 43  ? 11.37344  25.61374 -10.77681 1.000 9.43898  ? 43  PHE C C   1 
ATOM   2635 O O   . PHE C 1 43  ? 10.71143  26.18443 -9.89750  1.000 10.24605 ? 43  PHE C O   1 
ATOM   2636 C CB  . PHE C 1 43  ? 13.64731  26.64415 -10.63230 1.000 8.85015  ? 43  PHE C CB  1 
ATOM   2637 C CG  . PHE C 1 43  ? 14.89883  26.99291 -11.37060 1.000 9.32599  ? 43  PHE C CG  1 
ATOM   2638 C CD1 . PHE C 1 43  ? 15.68711  26.00062 -11.93706 1.000 9.49329  ? 43  PHE C CD1 1 
ATOM   2639 C CD2 . PHE C 1 43  ? 15.26915  28.31625 -11.53571 1.000 9.41606  ? 43  PHE C CD2 1 
ATOM   2640 C CE1 . PHE C 1 43  ? 16.83679  26.31972 -12.64047 1.000 10.66179 ? 43  PHE C CE1 1 
ATOM   2641 C CE2 . PHE C 1 43  ? 16.41811  28.65627 -12.23680 1.000 9.49032  ? 43  PHE C CE2 1 
ATOM   2642 C CZ  . PHE C 1 43  ? 17.20758  27.64771 -12.78903 1.000 10.22925 ? 43  PHE C CZ  1 
ATOM   2643 N N   . GLN C 1 44  ? 11.24529  24.32473 -11.06540 1.000 8.44312  ? 44  GLN C N   1 
ATOM   2644 C CA  . GLN C 1 44  ? 10.27198  23.44102 -10.43995 1.000 7.64067  ? 44  GLN C CA  1 
ATOM   2645 C C   . GLN C 1 44  ? 11.06124  22.35237 -9.72217  1.000 9.36337  ? 44  GLN C C   1 
ATOM   2646 O O   . GLN C 1 44  ? 11.58263  21.42798 -10.35332 1.000 10.37333 ? 44  GLN C O   1 
ATOM   2647 C CB  . GLN C 1 44  ? 9.31472   22.84220 -11.47748 1.000 10.11209 ? 44  GLN C CB  1 
ATOM   2648 C CG  . GLN C 1 44  ? 8.50365   23.89330 -12.24148 1.000 8.83890  ? 44  GLN C CG  1 
ATOM   2649 C CD  . GLN C 1 44  ? 7.39088   24.48084 -11.40011 1.000 10.76687 ? 44  GLN C CD  1 
ATOM   2650 O OE1 . GLN C 1 44  ? 6.52278   23.75505 -10.90925 1.000 15.00671 ? 44  GLN C OE1 1 
ATOM   2651 N NE2 . GLN C 1 44  ? 7.39789   25.79381 -11.24361 1.000 8.25803  ? 44  GLN C NE2 1 
ATOM   2652 N N   . GLU C 1 45  ? 11.17324  22.49224 -8.41330  1.000 9.69829  ? 45  GLU C N   1 
ATOM   2653 C CA  . GLU C 1 45  ? 11.93402  21.57414 -7.58338  1.000 11.77262 ? 45  GLU C CA  1 
ATOM   2654 C C   . GLU C 1 45  ? 11.03354  20.51685 -6.96695  1.000 11.32641 ? 45  GLU C C   1 
ATOM   2655 O O   . GLU C 1 45  ? 9.93645   20.82057 -6.48653  1.000 11.56479 ? 45  GLU C O   1 
ATOM   2656 C CB  . GLU C 1 45  ? 12.63990  22.34434 -6.46949  1.000 13.14644 ? 45  GLU C CB  1 
ATOM   2657 C CG  . GLU C 1 45  ? 13.86190  23.09231 -6.91377  1.000 13.35241 ? 45  GLU C CG  1 
ATOM   2658 C CD  . GLU C 1 45  ? 14.38537  24.00195 -5.82109  1.000 18.71280 ? 45  GLU C CD  1 
ATOM   2659 O OE1 . GLU C 1 45  ? 13.60306  24.83366 -5.31752  1.000 16.83848 ? 45  GLU C OE1 1 
ATOM   2660 O OE2 . GLU C 1 45  ? 15.57221  23.85131 -5.45167  1.000 24.85908 ? 45  GLU C OE2 1 
ATOM   2661 N N   . GLN C 1 46  ? 11.52646  19.27975 -6.94400  1.000 9.72231  ? 46  GLN C N   1 
ATOM   2662 C CA  . GLN C 1 46  ? 10.86102  18.14836 -6.32452  1.000 10.58364 ? 46  GLN C CA  1 
ATOM   2663 C C   . GLN C 1 46  ? 11.91237  17.34269 -5.57746  1.000 12.41387 ? 46  GLN C C   1 
ATOM   2664 O O   . GLN C 1 46  ? 13.08655  17.35851 -5.95710  1.000 12.77385 ? 46  GLN C O   1 
ATOM   2665 C CB  . GLN C 1 46  ? 10.17377  17.25422 -7.37014  1.000 11.95348 ? 46  GLN C CB  1 
ATOM   2666 C CG  . GLN C 1 46  ? 8.95936   17.87683 -8.01219  1.000 11.61697 ? 46  GLN C CG  1 
ATOM   2667 C CD  . GLN C 1 46  ? 7.76980   17.89459 -7.08020  1.000 11.23319 ? 46  GLN C CD  1 
ATOM   2668 O OE1 . GLN C 1 46  ? 7.51406   16.92721 -6.36094  1.000 14.13314 ? 46  GLN C OE1 1 
ATOM   2669 N NE2 . GLN C 1 46  ? 7.01495   18.98998 -7.10751  1.000 15.17699 ? 46  GLN C NE2 1 
ATOM   2670 N N   . PRO C 1 47  ? 11.52572  16.61648 -4.53328  1.000 15.64092 ? 47  PRO C N   1 
ATOM   2671 C CA  . PRO C 1 47  ? 12.52591  15.82241 -3.80513  1.000 11.81030 ? 47  PRO C CA  1 
ATOM   2672 C C   . PRO C 1 47  ? 13.21635  14.82966 -4.72453  1.000 13.87540 ? 47  PRO C C   1 
ATOM   2673 O O   . PRO C 1 47  ? 12.61033  14.28623 -5.65014  1.000 16.42712 ? 47  PRO C O   1 
ATOM   2674 C CB  . PRO C 1 47  ? 11.70358  15.10274 -2.73425  1.000 14.61045 ? 47  PRO C CB  1 
ATOM   2675 C CG  . PRO C 1 47  ? 10.28854  15.12560 -3.24464  1.000 21.02981 ? 47  PRO C CG  1 
ATOM   2676 C CD  . PRO C 1 47  ? 10.16647  16.42019 -4.00552  1.000 15.26979 ? 47  PRO C CD  1 
ATOM   2677 N N   . ALA C 1 48  ? 14.50713  14.59800 -4.47049  1.000 15.24110 ? 48  ALA C N   1 
ATOM   2678 C CA  . ALA C 1 48  ? 15.21121  13.56249 -5.21718  1.000 15.40851 ? 48  ALA C CA  1 
ATOM   2679 C C   . ALA C 1 48  ? 14.49020  12.23157 -5.05764  1.000 15.40053 ? 48  ALA C C   1 
ATOM   2680 O O   . ALA C 1 48  ? 13.94455  11.92087 -3.99579  1.000 17.06632 ? 48  ALA C O   1 
ATOM   2681 C CB  . ALA C 1 48  ? 16.65910  13.43473 -4.74096  1.000 16.29984 ? 48  ALA C CB  1 
ATOM   2682 N N   . GLY C 1 49  ? 14.46180  11.45331 -6.13327  1.000 16.20654 ? 49  GLY C N   1 
ATOM   2683 C CA  . GLY C 1 49  ? 13.73232  10.20502 -6.14851  1.000 15.84894 ? 49  GLY C CA  1 
ATOM   2684 C C   . GLY C 1 49  ? 12.36472  10.28781 -6.78649  1.000 16.25312 ? 49  GLY C C   1 
ATOM   2685 O O   . GLY C 1 49  ? 11.68538  9.25751  -6.90063  1.000 15.83217 ? 49  GLY C O   1 
ATOM   2686 N N   . ASN C 1 50  ? 11.93575  11.47897 -7.19539  1.000 15.18844 ? 50  ASN C N   1 
ATOM   2687 C CA  . ASN C 1 50  ? 10.68103  11.61576 -7.91722  1.000 11.79135 ? 50  ASN C CA  1 
ATOM   2688 C C   . ASN C 1 50  ? 10.84139  11.41827 -9.41489  1.000 14.16861 ? 50  ASN C C   1 
ATOM   2689 O O   . ASN C 1 50  ? 9.83653   11.41768 -10.12742 1.000 12.52487 ? 50  ASN C O   1 
ATOM   2690 C CB  . ASN C 1 50  ? 10.06029  12.99211 -7.64755  1.000 11.16328 ? 50  ASN C CB  1 
ATOM   2691 C CG  . ASN C 1 50  ? 9.18235   12.99121 -6.41672  1.000 13.10922 ? 50  ASN C CG  1 
ATOM   2692 O OD1 . ASN C 1 50  ? 9.23730   12.06380 -5.60318  1.000 15.94529 ? 50  ASN C OD1 1 
ATOM   2693 N ND2 . ASN C 1 50  ? 8.36257   14.03806 -6.26379  1.000 15.23245 ? 50  ASN C ND2 1 
ATOM   2694 N N   . VAL C 1 51  ? 12.05955  11.23774 -9.90833  1.000 13.61473 ? 51  VAL C N   1 
ATOM   2695 C CA  . VAL C 1 51  ? 12.30117  10.98518 -11.32776 1.000 12.56972 ? 51  VAL C CA  1 
ATOM   2696 C C   . VAL C 1 51  ? 12.61746  9.51091  -11.50982 1.000 14.37999 ? 51  VAL C C   1 
ATOM   2697 O O   . VAL C 1 51  ? 13.45817  8.95998  -10.78732 1.000 15.12105 ? 51  VAL C O   1 
ATOM   2698 C CB  . VAL C 1 51  ? 13.44891  11.84767 -11.88019 1.000 13.01029 ? 51  VAL C CB  1 
ATOM   2699 C CG1 . VAL C 1 51  ? 13.74012  11.46722 -13.33471 1.000 12.45277 ? 51  VAL C CG1 1 
ATOM   2700 C CG2 . VAL C 1 51  ? 13.15441  13.34579 -11.75251 1.000 12.20637 ? 51  VAL C CG2 1 
ATOM   2701 N N   . PHE C 1 52  ? 11.97965  8.88456  -12.49817 1.000 15.33300 ? 52  PHE C N   1 
ATOM   2702 C CA  . PHE C 1 52  ? 12.25630  7.50813  -12.88255 1.000 15.27823 ? 52  PHE C CA  1 
ATOM   2703 C C   . PHE C 1 52  ? 12.65422  7.46762  -14.35129 1.000 13.66387 ? 52  PHE C C   1 
ATOM   2704 O O   . PHE C 1 52  ? 12.03377  8.11983  -15.18753 1.000 13.03527 ? 52  PHE C O   1 
ATOM   2705 C CB  . PHE C 1 52  ? 11.04148  6.61247  -12.63387 1.000 13.38842 ? 52  PHE C CB  1 
ATOM   2706 C CG  . PHE C 1 52  ? 10.71805  6.43416  -11.18881 1.000 16.33445 ? 52  PHE C CG  1 
ATOM   2707 C CD1 . PHE C 1 52  ? 10.11978  7.45762  -10.46499 1.000 12.60154 ? 52  PHE C CD1 1 
ATOM   2708 C CD2 . PHE C 1 52  ? 11.00217  5.23102  -10.54330 1.000 17.35488 ? 52  PHE C CD2 1 
ATOM   2709 C CE1 . PHE C 1 52  ? 9.81761   7.29891  -9.11277  1.000 18.15027 ? 52  PHE C CE1 1 
ATOM   2710 C CE2 . PHE C 1 52  ? 10.70027  5.06370  -9.20213  1.000 14.61281 ? 52  PHE C CE2 1 
ATOM   2711 C CZ  . PHE C 1 52  ? 10.10819  6.09864  -8.48307  1.000 21.28532 ? 52  PHE C CZ  1 
ATOM   2712 N N   . LEU C 1 53  ? 13.70310  6.71198  -14.66637 1.000 14.76169 ? 53  LEU C N   1 
ATOM   2713 C CA  . LEU C 1 53  ? 14.15503  6.54136  -16.04286 1.000 15.82566 ? 53  LEU C CA  1 
ATOM   2714 C C   . LEU C 1 53  ? 14.14465  5.05220  -16.34352 1.000 19.25008 ? 53  LEU C C   1 
ATOM   2715 O O   . LEU C 1 53  ? 14.85908  4.28535  -15.68817 1.000 19.16097 ? 53  LEU C O   1 
ATOM   2716 C CB  . LEU C 1 53  ? 15.55041  7.14323  -16.26583 1.000 17.70053 ? 53  LEU C CB  1 
ATOM   2717 C CG  . LEU C 1 53  ? 15.68796  8.66565  -16.10559 1.000 17.11254 ? 53  LEU C CG  1 
ATOM   2718 C CD1 . LEU C 1 53  ? 17.13555  9.15661  -16.23204 1.000 14.30524 ? 53  LEU C CD1 1 
ATOM   2719 C CD2 . LEU C 1 53  ? 14.81323  9.35903  -17.13605 1.000 15.20741 ? 53  LEU C CD2 1 
ATOM   2720 N N   . GLY C 1 54  ? 13.33043  4.64439  -17.31560 1.000 14.96258 ? 54  GLY C N   1 
ATOM   2721 C CA  . GLY C 1 54  ? 13.13800  3.22080  -17.56619 1.000 16.10812 ? 54  GLY C CA  1 
ATOM   2722 C C   . GLY C 1 54  ? 12.63908  2.43623  -16.37145 1.000 16.98673 ? 54  GLY C C   1 
ATOM   2723 O O   . GLY C 1 54  ? 12.93285  1.24151  -16.25614 1.000 19.98777 ? 54  GLY C O   1 
ATOM   2724 N N   . GLY C 1 55  ? 11.86701  3.06833  -15.48569 1.000 13.25633 ? 55  GLY C N   1 
ATOM   2725 C CA  . GLY C 1 55  ? 11.38871  2.44557  -14.26515 1.000 17.23895 ? 55  GLY C CA  1 
ATOM   2726 C C   . GLY C 1 55  ? 12.35523  2.50148  -13.09647 1.000 19.18782 ? 55  GLY C C   1 
ATOM   2727 O O   . GLY C 1 55  ? 11.99251  2.07530  -11.98845 1.000 21.48257 ? 55  GLY C O   1 
ATOM   2728 N N   . VAL C 1 56  ? 13.55446  3.03550  -13.29519 1.000 17.64711 ? 56  VAL C N   1 
ATOM   2729 C CA  . VAL C 1 56  ? 14.58789  3.07660  -12.26471 1.000 19.86162 ? 56  VAL C CA  1 
ATOM   2730 C C   . VAL C 1 56  ? 14.55731  4.43766  -11.58188 1.000 17.33416 ? 56  VAL C C   1 
ATOM   2731 O O   . VAL C 1 56  ? 14.71099  5.47390  -12.24219 1.000 17.32251 ? 56  VAL C O   1 
ATOM   2732 C CB  . VAL C 1 56  ? 15.97468  2.79557  -12.86087 1.000 20.77563 ? 56  VAL C CB  1 
ATOM   2733 C CG1 . VAL C 1 56  ? 17.05463  2.95939  -11.79357 1.000 18.05485 ? 56  VAL C CG1 1 
ATOM   2734 C CG2 . VAL C 1 56  ? 16.01188  1.39812  -13.47944 1.000 27.01388 ? 56  VAL C CG2 1 
ATOM   2735 N N   . GLN C 1 57  ? 14.38840  4.43279  -10.25655 1.000 17.27952 ? 57  GLN C N   1 
ATOM   2736 C CA  . GLN C 1 57  ? 14.45388  5.66616  -9.47235  1.000 17.99232 ? 57  GLN C CA  1 
ATOM   2737 C C   . GLN C 1 57  ? 15.81500  6.33308  -9.61172  1.000 19.13982 ? 57  GLN C C   1 
ATOM   2738 O O   . GLN C 1 57  ? 16.85758  5.67827  -9.48892  1.000 19.58279 ? 57  GLN C O   1 
ATOM   2739 C CB  . GLN C 1 57  ? 14.18125  5.38373  -7.99776  1.000 19.70823 ? 57  GLN C CB  1 
ATOM   2740 C CG  . GLN C 1 57  ? 14.03333  6.63526  -7.16215  1.000 17.89701 ? 57  GLN C CG  1 
ATOM   2741 C CD  . GLN C 1 57  ? 13.42069  6.34230  -5.81096  1.000 26.03231 ? 57  GLN C CD  1 
ATOM   2742 O OE1 . GLN C 1 57  ? 14.00731  6.64291  -4.77516  1.000 41.34551 ? 57  GLN C OE1 1 
ATOM   2743 N NE2 . GLN C 1 57  ? 12.24092  5.73231  -5.81332  1.000 36.80062 ? 57  GLN C NE2 1 
ATOM   2744 N N   . GLN C 1 58  ? 15.80175  7.64316  -9.86055  1.000 15.69984 ? 58  GLN C N   1 
ATOM   2745 C CA  . GLN C 1 58  ? 17.01493  8.42147  -10.04586 1.000 16.59535 ? 58  GLN C CA  1 
ATOM   2746 C C   . GLN C 1 58  ? 17.40949  9.16157  -8.77384  1.000 15.99063 ? 58  GLN C C   1 
ATOM   2747 O O   . GLN C 1 58  ? 16.60399  9.37198  -7.86181  1.000 17.36221 ? 58  GLN C O   1 
ATOM   2748 C CB  . GLN C 1 58  ? 16.84240  9.43695  -11.17591 1.000 17.68191 ? 58  GLN C CB  1 
ATOM   2749 C CG  . GLN C 1 58  ? 16.47385  8.81347  -12.49756 1.000 17.28198 ? 58  GLN C CG  1 
ATOM   2750 C CD  . GLN C 1 58  ? 17.53594  7.84930  -12.96505 1.000 20.97059 ? 58  GLN C CD  1 
ATOM   2751 O OE1 . GLN C 1 58  ? 18.66351  8.25127  -13.25114 1.000 25.42460 ? 58  GLN C OE1 1 
ATOM   2752 N NE2 . GLN C 1 58  ? 17.18909  6.56761  -13.02647 1.000 20.49000 ? 58  GLN C NE2 1 
ATOM   2753 N N   . GLY C 1 59  ? 18.67916  9.57181  -8.74215  1.000 19.30806 ? 59  GLY C N   1 
ATOM   2754 C CA  . GLY C 1 59  ? 19.16062  10.53582 -7.77444  1.000 19.63689 ? 59  GLY C CA  1 
ATOM   2755 C C   . GLY C 1 59  ? 18.69834  11.93060 -8.13590  1.000 17.78792 ? 59  GLY C C   1 
ATOM   2756 O O   . GLY C 1 59  ? 17.62307  12.12902 -8.71655  1.000 22.80846 ? 59  GLY C O   1 
ATOM   2757 N N   . GLY C 1 60  ? 19.50780  12.91269 -7.79876  1.000 25.08608 ? 60  GLY C N   1 
ATOM   2758 C CA  . GLY C 1 60  ? 19.04070  14.26769 -7.97602  1.000 22.16536 ? 60  GLY C CA  1 
ATOM   2759 C C   . GLY C 1 60  ? 19.62580  14.99769 -9.16119  1.000 19.78595 ? 60  GLY C C   1 
ATOM   2760 O O   . GLY C 1 60  ? 19.53185  16.22631 -9.22081  1.000 19.59405 ? 60  GLY C O   1 
ATOM   2761 N N   . ASP C 1 61  ? 20.22508  14.28206 -10.11617 1.000 14.38664 ? 61  ASP C N   1 
ATOM   2762 C CA  . ASP C 1 61  ? 20.96954  14.98230 -11.15742 1.000 14.75252 ? 61  ASP C CA  1 
ATOM   2763 C C   . ASP C 1 61  ? 20.15625  15.30731 -12.40651 1.000 14.82157 ? 61  ASP C C   1 
ATOM   2764 O O   . ASP C 1 61  ? 20.58789  16.16811 -13.18528 1.000 16.78727 ? 61  ASP C O   1 
ATOM   2765 C CB  . ASP C 1 61  ? 22.20446  14.18019 -11.58105 1.000 20.03650 ? 61  ASP C CB  1 
ATOM   2766 C CG  . ASP C 1 61  ? 23.42165  14.48763 -10.72534 1.000 27.58538 ? 61  ASP C CG  1 
ATOM   2767 O OD1 . ASP C 1 61  ? 24.55613  14.27558 -11.21185 1.000 35.73896 ? 61  ASP C OD1 1 
ATOM   2768 O OD2 . ASP C 1 61  ? 23.24824  14.95707 -9.58333  1.000 21.30459 ? 61  ASP C OD2 1 
ATOM   2769 N N   . THR C 1 62  ? 19.02231  14.64870 -12.64030 1.000 14.96294 ? 62  THR C N   1 
ATOM   2770 C CA  . THR C 1 62  ? 18.29454  14.87689 -13.88919 1.000 13.87769 ? 62  THR C CA  1 
ATOM   2771 C C   . THR C 1 62  ? 17.80807  16.31968 -13.97391 1.000 12.72513 ? 62  THR C C   1 
ATOM   2772 O O   . THR C 1 62  ? 17.37496  16.91018 -12.97826 1.000 12.76819 ? 62  THR C O   1 
ATOM   2773 C CB  . THR C 1 62  ? 17.09708  13.92847 -14.01129 1.000 14.33112 ? 62  THR C CB  1 
ATOM   2774 O OG1 . THR C 1 62  ? 17.51195  12.58502 -13.74717 1.000 18.31505 ? 62  THR C OG1 1 
ATOM   2775 C CG2 . THR C 1 62  ? 16.48319  13.97977 -15.42479 1.000 16.36877 ? 62  THR C CG2 1 
ATOM   2776 N N   . ILE C 1 63  ? 17.91626  16.90179 -15.16548 1.000 12.88438 ? 63  ILE C N   1 
ATOM   2777 C CA  . ILE C 1 63  ? 17.36665  18.22462 -15.42736 1.000 11.01434 ? 63  ILE C CA  1 
ATOM   2778 C C   . ILE C 1 63  ? 16.50256  18.09031 -16.67111 1.000 10.06221 ? 63  ILE C C   1 
ATOM   2779 O O   . ILE C 1 63  ? 16.99778  17.63665 -17.70553 1.000 12.11611 ? 63  ILE C O   1 
ATOM   2780 C CB  . ILE C 1 63  ? 18.45380  19.27486 -15.67838 1.000 13.75138 ? 63  ILE C CB  1 
ATOM   2781 C CG1 . ILE C 1 63  ? 19.28246  19.51987 -14.42511 1.000 14.43600 ? 63  ILE C CG1 1 
ATOM   2782 C CG2 . ILE C 1 63  ? 17.78468  20.61160 -16.03297 1.000 12.66854 ? 63  ILE C CG2 1 
ATOM   2783 C CD1 . ILE C 1 63  ? 20.54254  20.30401 -14.71844 1.000 20.05922 ? 63  ILE C CD1 1 
ATOM   2784 N N   . PHE C 1 64  ? 15.22415  18.47303 -16.58045 1.000 10.85838 ? 64  PHE C N   1 
ATOM   2785 C CA  . PHE C 1 64  ? 14.34575  18.51507 -17.75540 1.000 10.48794 ? 64  PHE C CA  1 
ATOM   2786 C C   . PHE C 1 64  ? 13.92348  19.95608 -18.01092 1.000 9.98236  ? 64  PHE C C   1 
ATOM   2787 O O   . PHE C 1 64  ? 13.31878  20.59053 -17.13890 1.000 9.08108  ? 64  PHE C O   1 
ATOM   2788 C CB  . PHE C 1 64  ? 13.10783  17.62670 -17.58652 1.000 8.22476  ? 64  PHE C CB  1 
ATOM   2789 C CG  . PHE C 1 64  ? 12.07694  17.78754 -18.70161 1.000 9.24860  ? 64  PHE C CG  1 
ATOM   2790 C CD1 . PHE C 1 64  ? 12.46998  17.83003 -20.02448 1.000 9.64226  ? 64  PHE C CD1 1 
ATOM   2791 C CD2 . PHE C 1 64  ? 10.72468  17.89999 -18.40509 1.000 10.07400 ? 64  PHE C CD2 1 
ATOM   2792 C CE1 . PHE C 1 64  ? 11.52988  17.97482 -21.04131 1.000 8.87706  ? 64  PHE C CE1 1 
ATOM   2793 C CE2 . PHE C 1 64  ? 9.77647   18.03857 -19.43105 1.000 9.63011  ? 64  PHE C CE2 1 
ATOM   2794 C CZ  . PHE C 1 64  ? 10.19003  18.07439 -20.73352 1.000 9.17871  ? 64  PHE C CZ  1 
ATOM   2795 N N   . VAL C 1 65  ? 14.25136  20.46553 -19.19562 1.000 8.05391  ? 65  VAL C N   1 
ATOM   2796 C CA  . VAL C 1 65  ? 13.89891  21.81766 -19.61075 1.000 7.44348  ? 65  VAL C CA  1 
ATOM   2797 C C   . VAL C 1 65  ? 12.76574  21.69615 -20.61702 1.000 9.04146  ? 65  VAL C C   1 
ATOM   2798 O O   . VAL C 1 65  ? 12.93774  21.08533 -21.67837 1.000 11.17378 ? 65  VAL C O   1 
ATOM   2799 C CB  . VAL C 1 65  ? 15.09456  22.55243 -20.23121 1.000 7.73057  ? 65  VAL C CB  1 
ATOM   2800 C CG1 . VAL C 1 65  ? 14.69483  23.94322 -20.74507 1.000 11.43041 ? 65  VAL C CG1 1 
ATOM   2801 C CG2 . VAL C 1 65  ? 16.28168  22.64217 -19.23822 1.000 11.52893 ? 65  VAL C CG2 1 
ATOM   2802 N N   . HIS C 1 66  ? 11.61269  22.25981 -20.27540 1.000 8.36078  ? 66  HIS C N   1 
ATOM   2803 C CA  . HIS C 1 66  ? 10.45966  22.30741 -21.15766 1.000 8.03017  ? 66  HIS C CA  1 
ATOM   2804 C C   . HIS C 1 66  ? 10.31471  23.76322 -21.59160 1.000 8.25801  ? 66  HIS C C   1 
ATOM   2805 O O   . HIS C 1 66  ? 9.87016   24.60824 -20.80847 1.000 8.60562  ? 66  HIS C O   1 
ATOM   2806 C CB  . HIS C 1 66  ? 9.21580   21.80261 -20.44038 1.000 7.38318  ? 66  HIS C CB  1 
ATOM   2807 C CG  . HIS C 1 66  ? 8.05274   21.56367 -21.35051 1.000 6.60013  ? 66  HIS C CG  1 
ATOM   2808 N ND1 . HIS C 1 66  ? 6.77308   21.35121 -20.87781 1.000 9.04980  ? 66  HIS C ND1 1 
ATOM   2809 C CD2 . HIS C 1 66  ? 7.97271   21.51075 -22.70152 1.000 9.31502  ? 66  HIS C CD2 1 
ATOM   2810 C CE1 . HIS C 1 66  ? 5.95987   21.15877 -21.89860 1.000 12.25546 ? 66  HIS C CE1 1 
ATOM   2811 N NE2 . HIS C 1 66  ? 6.65984   21.25058 -23.01704 1.000 10.08623 ? 66  HIS C NE2 1 
ATOM   2812 N N   . GLY C 1 67  ? 10.73196  24.06212 -22.82113 1.000 7.42182  ? 67  GLY C N   1 
ATOM   2813 C CA  . GLY C 1 67  ? 10.66117  25.41453 -23.33959 1.000 7.98176  ? 67  GLY C CA  1 
ATOM   2814 C C   . GLY C 1 67  ? 9.36949   25.62230 -24.10576 1.000 7.82546  ? 67  GLY C C   1 
ATOM   2815 O O   . GLY C 1 67  ? 8.98813   24.79368 -24.93214 1.000 9.43955  ? 67  GLY C O   1 
ATOM   2816 N N   . LEU C 1 68  ? 8.67788   26.71575 -23.79459 1.000 8.18682  ? 68  LEU C N   1 
ATOM   2817 C CA  . LEU C 1 68  ? 7.40498   27.05703 -24.42954 1.000 7.25038  ? 68  LEU C CA  1 
ATOM   2818 C C   . LEU C 1 68  ? 7.61627   28.31624 -25.26139 1.000 8.67123  ? 68  LEU C C   1 
ATOM   2819 O O   . LEU C 1 68  ? 7.86287   29.39586 -24.71300 1.000 9.56928  ? 68  LEU C O   1 
ATOM   2820 C CB  . LEU C 1 68  ? 6.32062   27.25651 -23.37310 1.000 6.72804  ? 68  LEU C CB  1 
ATOM   2821 C CG  . LEU C 1 68  ? 6.17283   26.02070 -22.46597 1.000 8.04552  ? 68  LEU C CG  1 
ATOM   2822 C CD1 . LEU C 1 68  ? 5.31265   26.34211 -21.25885 1.000 10.81073 ? 68  LEU C CD1 1 
ATOM   2823 C CD2 . LEU C 1 68  ? 5.61836   24.79548 -23.21854 1.000 12.65771 ? 68  LEU C CD2 1 
ATOM   2824 N N   . HIS C 1 69  ? 7.51098   28.16597 -26.58387 1.000 9.96231  ? 69  HIS C N   1 
ATOM   2825 C CA  . HIS C 1 69  ? 7.91554   29.14601 -27.58025 1.000 7.79964  ? 69  HIS C CA  1 
ATOM   2826 C C   . HIS C 1 69  ? 6.72495   29.54350 -28.43903 1.000 7.34572  ? 69  HIS C C   1 
ATOM   2827 O O   . HIS C 1 69  ? 5.73951   28.81494 -28.52080 1.000 8.89240  ? 69  HIS C O   1 
ATOM   2828 C CB  . HIS C 1 69  ? 8.96664   28.57030 -28.54177 1.000 7.78302  ? 69  HIS C CB  1 
ATOM   2829 C CG  . HIS C 1 69  ? 10.29770  28.24568 -27.92685 1.000 10.66463 ? 69  HIS C CG  1 
ATOM   2830 N ND1 . HIS C 1 69  ? 11.25535  27.53646 -28.61731 1.000 16.33113 ? 69  HIS C ND1 1 
ATOM   2831 C CD2 . HIS C 1 69  ? 10.85625  28.56694 -26.73639 1.000 12.56702 ? 69  HIS C CD2 1 
ATOM   2832 C CE1 . HIS C 1 69  ? 12.33439  27.39995 -27.86492 1.000 12.43871 ? 69  HIS C CE1 1 
ATOM   2833 N NE2 . HIS C 1 69  ? 12.12270  28.02270 -26.72254 1.000 9.13247  ? 69  HIS C NE2 1 
ATOM   2834 N N   . ARG C 1 70  ? 6.86416   30.67619 -29.13235 1.000 7.59944  ? 70  ARG C N   1 
ATOM   2835 C CA  . ARG C 1 70  ? 6.00656   30.98038 -30.27565 1.000 7.64843  ? 70  ARG C CA  1 
ATOM   2836 C C   . ARG C 1 70  ? 6.37817   30.14890 -31.48690 1.000 9.76892  ? 70  ARG C C   1 
ATOM   2837 O O   . ARG C 1 70  ? 7.56176   29.93104 -31.76827 1.000 9.40426  ? 70  ARG C O   1 
ATOM   2838 C CB  . ARG C 1 70  ? 6.11712   32.45480 -30.68129 1.000 9.74849  ? 70  ARG C CB  1 
ATOM   2839 C CG  . ARG C 1 70  ? 5.70302   33.41491 -29.61032 1.000 10.02396 ? 70  ARG C CG  1 
ATOM   2840 C CD  . ARG C 1 70  ? 6.12118   34.82485 -29.97026 1.000 11.23930 ? 70  ARG C CD  1 
ATOM   2841 N NE  . ARG C 1 70  ? 7.41121   35.10843 -29.35912 1.000 13.99702 ? 70  ARG C NE  1 
ATOM   2842 C CZ  . ARG C 1 70  ? 8.24215   36.06861 -29.74809 1.000 17.14745 ? 70  ARG C CZ  1 
ATOM   2843 N NH1 . ARG C 1 70  ? 7.87448   36.98948 -30.62339 1.000 15.87635 ? 70  ARG C NH1 1 
ATOM   2844 N NH2 . ARG C 1 70  ? 9.46196   36.12592 -29.22025 1.000 16.10943 ? 70  ARG C NH2 1 
ATOM   2845 N N   . GLU C 1 71  ? 5.35393   29.73836 -32.23594 1.000 10.23010 ? 71  GLU C N   1 
ATOM   2846 C CA  . GLU C 1 71  ? 5.55898   29.21204 -33.57952 1.000 9.73515  ? 71  GLU C CA  1 
ATOM   2847 C C   . GLU C 1 71  ? 6.25027   30.23800 -34.46201 1.000 9.59797  ? 71  GLU C C   1 
ATOM   2848 O O   . GLU C 1 71  ? 6.07947   31.44683 -34.30015 1.000 11.85981 ? 71  GLU C O   1 
ATOM   2849 C CB  . GLU C 1 71  ? 4.21969   28.85448 -34.22431 1.000 11.61959 ? 71  GLU C CB  1 
ATOM   2850 C CG  . GLU C 1 71  ? 3.53694   27.65802 -33.63370 1.000 12.63975 ? 71  GLU C CG  1 
ATOM   2851 C CD  . GLU C 1 71  ? 2.14391   27.46455 -34.18957 1.000 17.41538 ? 71  GLU C CD  1 
ATOM   2852 O OE1 . GLU C 1 71  ? 1.67063   28.34827 -34.93032 1.000 17.23417 ? 71  GLU C OE1 1 
ATOM   2853 O OE2 . GLU C 1 71  ? 1.51825   26.43845 -33.85590 1.000 17.70165 ? 71  GLU C OE2 1 
ATOM   2854 N N   . GLY C 1 72  ? 7.01097   29.73941 -35.43697 1.000 8.39416  ? 72  GLY C N   1 
ATOM   2855 C CA  . GLY C 1 72  ? 7.55113   30.63290 -36.44138 1.000 9.57539  ? 72  GLY C CA  1 
ATOM   2856 C C   . GLY C 1 72  ? 9.03057   30.50640 -36.71093 1.000 11.69587 ? 72  GLY C C   1 
ATOM   2857 O O   . GLY C 1 72  ? 9.51305   31.05704 -37.70137 1.000 11.13568 ? 72  GLY C O   1 
ATOM   2858 N N   . ARG C 1 73  ? 9.75961   29.78995 -35.86230 1.000 9.77614  ? 73  ARG C N   1 
ATOM   2859 C CA  . ARG C 1 73  ? 11.19117  29.64412 -36.09155 1.000 9.12655  ? 73  ARG C CA  1 
ATOM   2860 C C   . ARG C 1 73  ? 11.49744  28.35766 -36.85250 1.000 8.60778  ? 73  ARG C C   1 
ATOM   2861 O O   . ARG C 1 73  ? 10.69759  27.41739 -36.89620 1.000 11.25275 ? 73  ARG C O   1 
ATOM   2862 C CB  . ARG C 1 73  ? 11.94191  29.68228 -34.75987 1.000 11.60289 ? 73  ARG C CB  1 
ATOM   2863 C CG  . ARG C 1 73  ? 11.67387  30.97667 -34.03158 1.000 13.52329 ? 73  ARG C CG  1 
ATOM   2864 C CD  . ARG C 1 73  ? 12.74424  31.30236 -33.00039 1.000 13.19470 ? 73  ARG C CD  1 
ATOM   2865 N NE  . ARG C 1 73  ? 12.39133  32.53816 -32.31383 1.000 13.04798 ? 73  ARG C NE  1 
ATOM   2866 C CZ  . ARG C 1 73  ? 11.63872  32.58575 -31.22474 1.000 17.43862 ? 73  ARG C CZ  1 
ATOM   2867 N NH1 . ARG C 1 73  ? 11.18415  31.47787 -30.64990 1.000 15.33031 ? 73  ARG C NH1 1 
ATOM   2868 N NH2 . ARG C 1 73  ? 11.32087  33.77318 -30.70770 1.000 17.37056 ? 73  ARG C NH2 1 
ATOM   2869 N N   . SER C 1 74  ? 12.67844  28.33085 -37.46551 1.000 8.63488  ? 74  SER C N   1 
ATOM   2870 C CA  . SER C 1 74  ? 13.08901  27.19299 -38.27209 1.000 9.92076  ? 74  SER C CA  1 
ATOM   2871 C C   . SER C 1 74  ? 13.53051  26.02950 -37.39991 1.000 10.20801 ? 74  SER C C   1 
ATOM   2872 O O   . SER C 1 74  ? 13.96948  26.20941 -36.25938 1.000 9.60384  ? 74  SER C O   1 
ATOM   2873 C CB  . SER C 1 74  ? 14.23497  27.58650 -39.21507 1.000 9.01429  ? 74  SER C CB  1 
ATOM   2874 O OG  . SER C 1 74  ? 15.44777  27.76797 -38.48472 1.000 11.15742 ? 74  SER C OG  1 
ATOM   2875 N N   . ALA C 1 75  ? 13.39318  24.82101 -37.94958 1.000 9.26815  ? 75  ALA C N   1 
ATOM   2876 C CA  . ALA C 1 75  ? 13.93591  23.64049 -37.28589 1.000 11.95901 ? 75  ALA C CA  1 
ATOM   2877 C C   . ALA C 1 75  ? 15.42663  23.80843 -37.02273 1.000 13.31419 ? 75  ALA C C   1 
ATOM   2878 O O   . ALA C 1 75  ? 15.93028  23.39485 -35.97149 1.000 11.55893 ? 75  ALA C O   1 
ATOM   2879 C CB  . ALA C 1 75  ? 13.67425  22.39126 -38.13569 1.000 12.52813 ? 75  ALA C CB  1 
ATOM   2880 N N   . ASP C 1 76  ? 16.14402  24.44915 -37.94627 1.000 12.13802 ? 76  ASP C N   1 
ATOM   2881 C CA  . ASP C 1 76  ? 17.58930  24.58186 -37.78632 1.000 11.67989 ? 76  ASP C CA  1 
ATOM   2882 C C   . ASP C 1 76  ? 17.90041  25.45675 -36.57260 1.000 12.85290 ? 76  ASP C C   1 
ATOM   2883 O O   . ASP C 1 76  ? 18.71509  25.08630 -35.72260 1.000 13.84973 ? 76  ASP C O   1 
ATOM   2884 C CB  . ASP C 1 76  ? 18.17715  25.14224 -39.09241 1.000 15.67092 ? 76  ASP C CB  1 
ATOM   2885 C CG  . ASP C 1 76  ? 19.61407  25.65253 -38.97469 1.000 24.87498 ? 76  ASP C CG  1 
ATOM   2886 O OD1 . ASP C 1 76  ? 20.27941  25.48686 -37.93823 1.000 32.36841 ? 76  ASP C OD1 1 
ATOM   2887 O OD2 . ASP C 1 76  ? 20.08695  26.23319 -39.97416 1.000 34.91908 ? 76  ASP C OD2 1 
ATOM   2888 N N   . LEU C 1 77  ? 17.21301  26.59382 -36.44814 1.000 11.60315 ? 77  LEU C N   1 
ATOM   2889 C CA  . LEU C 1 77  ? 17.42781  27.48542 -35.30842 1.000 10.24164 ? 77  LEU C CA  1 
ATOM   2890 C C   . LEU C 1 77  ? 17.04421  26.81285 -33.99180 1.000 12.07408 ? 77  LEU C C   1 
ATOM   2891 O O   . LEU C 1 77  ? 17.76068  26.92831 -32.98575 1.000 12.66738 ? 77  LEU C O   1 
ATOM   2892 C CB  . LEU C 1 77  ? 16.63106  28.78015 -35.52565 1.000 13.08642 ? 77  LEU C CB  1 
ATOM   2893 C CG  . LEU C 1 77  ? 16.94037  29.99438 -34.63925 1.000 15.04467 ? 77  LEU C CG  1 
ATOM   2894 C CD1 . LEU C 1 77  ? 16.20166  29.88303 -33.31132 1.000 20.69699 ? 77  LEU C CD1 1 
ATOM   2895 C CD2 . LEU C 1 77  ? 18.44681  30.17641 -34.42242 1.000 19.24941 ? 77  LEU C CD2 1 
ATOM   2896 N N   . LYS C 1 78  ? 15.90325  26.11558 -33.96847 1.000 12.26629 ? 78  LYS C N   1 
ATOM   2897 C CA  . LYS C 1 78  ? 15.48518  25.45365 -32.74191 1.000 9.27751  ? 78  LYS C CA  1 
ATOM   2898 C C   . LYS C 1 78  ? 16.46661  24.36443 -32.32993 1.000 11.11086 ? 78  LYS C C   1 
ATOM   2899 O O   . LYS C 1 78  ? 16.69174  24.15258 -31.13289 1.000 12.88159 ? 78  LYS C O   1 
ATOM   2900 C CB  . LYS C 1 78  ? 14.08430  24.87784 -32.91602 1.000 9.56521  ? 78  LYS C CB  1 
ATOM   2901 C CG  . LYS C 1 78  ? 12.98882  25.93357 -32.90117 1.000 11.94754 ? 78  LYS C CG  1 
ATOM   2902 C CD  . LYS C 1 78  ? 11.63156  25.27625 -33.14278 1.000 8.61204  ? 78  LYS C CD  1 
ATOM   2903 C CE  . LYS C 1 78  ? 11.41747  24.91939 -34.62253 1.000 9.02293  ? 78  LYS C CE  1 
ATOM   2904 N NZ  . LYS C 1 78  ? 10.05539  24.33202 -34.82459 1.000 10.76483 ? 78  LYS C NZ  1 
ATOM   2905 N N   . GLY C 1 79  ? 17.06656  23.67528 -33.30286 1.000 12.52659 ? 79  GLY C N   1 
ATOM   2906 C CA  . GLY C 1 79  ? 18.11892  22.72880 -32.97989 1.000 12.50260 ? 79  GLY C CA  1 
ATOM   2907 C C   . GLY C 1 79  ? 19.34000  23.40450 -32.37828 1.000 11.42171 ? 79  GLY C C   1 
ATOM   2908 O O   . GLY C 1 79  ? 19.87835  22.94573 -31.36813 1.000 13.47806 ? 79  GLY C O   1 
ATOM   2909 N N   . GLN C 1 80  ? 19.79384  24.49716 -32.99147 1.000 13.17424 ? 80  GLN C N   1 
ATOM   2910 C CA  . GLN C 1 80  ? 20.91597  25.24528 -32.42829 1.000 10.08089 ? 80  GLN C CA  1 
ATOM   2911 C C   . GLN C 1 80  ? 20.61838  25.70278 -31.00291 1.000 15.21949 ? 80  GLN C C   1 
ATOM   2912 O O   . GLN C 1 80  ? 21.48079  25.61885 -30.12279 1.000 13.91308 ? 80  GLN C O   1 
ATOM   2913 C CB  . GLN C 1 80  ? 21.22892  26.45302 -33.29348 1.000 15.86495 ? 80  GLN C CB  1 
ATOM   2914 C CG  . GLN C 1 80  ? 21.67574  26.13706 -34.69328 1.000 15.35827 ? 80  GLN C CG  1 
ATOM   2915 C CD  . GLN C 1 80  ? 21.90022  27.41006 -35.45641 1.000 21.53293 ? 80  GLN C CD  1 
ATOM   2916 O OE1 . GLN C 1 80  ? 22.46038  28.35952 -34.91734 1.000 27.08938 ? 80  GLN C OE1 1 
ATOM   2917 N NE2 . GLN C 1 80  ? 21.44121  27.45577 -36.70424 1.000 26.71826 ? 80  GLN C NE2 1 
ATOM   2918 N N   . LEU C 1 81  ? 19.39848  26.19682 -30.76042 1.000 11.49522 ? 81  LEU C N   1 
ATOM   2919 C CA  . LEU C 1 81  ? 19.04387  26.68444 -29.42540 1.000 8.60104  ? 81  LEU C CA  1 
ATOM   2920 C C   . LEU C 1 81  ? 18.98229  25.55002 -28.39662 1.000 11.82036 ? 81  LEU C C   1 
ATOM   2921 O O   . LEU C 1 81  ? 19.47475  25.70261 -27.27129 1.000 11.91220 ? 81  LEU C O   1 
ATOM   2922 C CB  . LEU C 1 81  ? 17.71322  27.44322 -29.51023 1.000 10.41406 ? 81  LEU C CB  1 
ATOM   2923 C CG  . LEU C 1 81  ? 17.09739  27.99353 -28.22325 1.000 9.11754  ? 81  LEU C CG  1 
ATOM   2924 C CD1 . LEU C 1 81  ? 18.10826  28.91251 -27.52071 1.000 12.52785 ? 81  LEU C CD1 1 
ATOM   2925 C CD2 . LEU C 1 81  ? 15.82745  28.73871 -28.57261 1.000 11.34603 ? 81  LEU C CD2 1 
ATOM   2926 N N   . ALA C 1 82  ? 18.39058  24.40697 -28.75729 1.000 9.87337  ? 82  ALA C N   1 
ATOM   2927 C CA  . ALA C 1 82  ? 18.34160  23.26607 -27.84272 1.000 10.16858 ? 82  ALA C CA  1 
ATOM   2928 C C   . ALA C 1 82  ? 19.74217  22.75977 -27.51624 1.000 12.54067 ? 82  ALA C C   1 
ATOM   2929 O O   . ALA C 1 82  ? 20.04680  22.45716 -26.35542 1.000 10.77386 ? 82  ALA C O   1 
ATOM   2930 C CB  . ALA C 1 82  ? 17.49298  22.14642 -28.44279 1.000 12.62244 ? 82  ALA C CB  1 
ATOM   2931 N N   . GLN C 1 83  ? 20.60610  22.64420 -28.52678 1.000 11.95985 ? 83  GLN C N   1 
ATOM   2932 C CA  . GLN C 1 83  ? 21.97425  22.23281 -28.25090 1.000 12.92304 ? 83  GLN C CA  1 
ATOM   2933 C C   . GLN C 1 83  ? 22.67136  23.23356 -27.33777 1.000 13.00277 ? 83  GLN C C   1 
ATOM   2934 O O   . GLN C 1 83  ? 23.39815  22.84037 -26.41550 1.000 13.41662 ? 83  GLN C O   1 
ATOM   2935 C CB  . GLN C 1 83  ? 22.74625  22.07029 -29.56095 1.000 14.69626 ? 83  GLN C CB  1 
ATOM   2936 C CG  . GLN C 1 83  ? 24.16027  21.49790 -29.35115 1.000 17.41766 ? 83  GLN C CG  1 
ATOM   2937 C CD  . GLN C 1 83  ? 24.12098  20.10013 -28.75712 1.000 17.66531 ? 83  GLN C CD  1 
ATOM   2938 O OE1 . GLN C 1 83  ? 23.54886  19.18296 -29.34306 1.000 20.49464 ? 83  GLN C OE1 1 
ATOM   2939 N NE2 . GLN C 1 83  ? 24.72287  19.93171 -27.58181 1.000 17.10480 ? 83  GLN C NE2 1 
ATOM   2940 N N   . ARG C 1 84  ? 22.45465  24.53177 -27.56603 1.000 11.98795 ? 84  ARG C N   1 
ATOM   2941 C CA  . ARG C 1 84  ? 23.13462  25.53195 -26.74449 1.000 12.04504 ? 84  ARG C CA  1 
ATOM   2942 C C   . ARG C 1 84  ? 22.65555  25.46429 -25.30485 1.000 14.71696 ? 84  ARG C C   1 
ATOM   2943 O O   . ARG C 1 84  ? 23.43929  25.68225 -24.36761 1.000 12.29611 ? 84  ARG C O   1 
ATOM   2944 C CB  . ARG C 1 84  ? 22.92681  26.94098 -27.30232 1.000 16.15821 ? 84  ARG C CB  1 
ATOM   2945 C CG  . ARG C 1 84  ? 23.82123  27.93524 -26.56762 1.000 17.23733 ? 84  ARG C CG  1 
ATOM   2946 C CD  . ARG C 1 84  ? 23.89314  29.30730 -27.20130 1.000 21.83793 ? 84  ARG C CD  1 
ATOM   2947 N NE  . ARG C 1 84  ? 24.34689  30.27856 -26.21568 1.000 23.09384 ? 84  ARG C NE  1 
ATOM   2948 C CZ  . ARG C 1 84  ? 24.51545  31.57373 -26.44598 1.000 23.93920 ? 84  ARG C CZ  1 
ATOM   2949 N NH1 . ARG C 1 84  ? 24.34392  32.09277 -27.65441 1.000 25.39696 ? 84  ARG C NH1 1 
ATOM   2950 N NH2 . ARG C 1 84  ? 24.86581  32.36976 -25.43833 1.000 22.46719 ? 84  ARG C NH2 1 
ATOM   2951 N N   . ILE C 1 85  ? 21.37004  25.16184 -25.10246 1.000 12.68884 ? 85  ILE C N   1 
ATOM   2952 C CA  . ILE C 1 85  ? 20.86474  25.01522 -23.74132 1.000 10.99310 ? 85  ILE C CA  1 
ATOM   2953 C C   . ILE C 1 85  ? 21.51800  23.81180 -23.06427 1.000 12.65357 ? 85  ILE C C   1 
ATOM   2954 O O   . ILE C 1 85  ? 21.99257  23.90326 -21.92568 1.000 13.09840 ? 85  ILE C O   1 
ATOM   2955 C CB  . ILE C 1 85  ? 19.32893  24.92152 -23.75069 1.000 9.44283  ? 85  ILE C CB  1 
ATOM   2956 C CG1 . ILE C 1 85  ? 18.73485  26.31400 -24.01238 1.000 14.14390 ? 85  ILE C CG1 1 
ATOM   2957 C CG2 . ILE C 1 85  ? 18.81993  24.35566 -22.44979 1.000 12.18431 ? 85  ILE C CG2 1 
ATOM   2958 C CD1 . ILE C 1 85  ? 17.24614  26.28033 -24.32378 1.000 12.98091 ? 85  ILE C CD1 1 
ATOM   2959 N N   . VAL C 1 86  ? 21.60206  22.67655 -23.77253 1.000 12.43378 ? 86  VAL C N   1 
ATOM   2960 C CA  . VAL C 1 86  ? 22.27677  21.50702 -23.20488 1.000 10.79479 ? 86  VAL C CA  1 
ATOM   2961 C C   . VAL C 1 86  ? 23.70588  21.86062 -22.80345 1.000 16.03223 ? 86  VAL C C   1 
ATOM   2962 O O   . VAL C 1 86  ? 24.13697  21.59170 -21.67715 1.000 14.03702 ? 86  VAL C O   1 
ATOM   2963 C CB  . VAL C 1 86  ? 22.26120  20.32432 -24.19115 1.000 13.22663 ? 86  VAL C CB  1 
ATOM   2964 C CG1 . VAL C 1 86  ? 23.12015  19.18105 -23.64654 1.000 14.32332 ? 86  VAL C CG1 1 
ATOM   2965 C CG2 . VAL C 1 86  ? 20.82780  19.84818 -24.45896 1.000 12.84618 ? 86  VAL C CG2 1 
ATOM   2966 N N   . ASP C 1 87  ? 24.45910  22.47179 -23.72053 1.000 14.81150 ? 87  ASP C N   1 
ATOM   2967 C CA  . ASP C 1 87  ? 25.87251  22.74034 -23.45097 1.000 13.29330 ? 87  ASP C CA  1 
ATOM   2968 C C   . ASP C 1 87  ? 26.03860  23.72298 -22.30652 1.000 16.55914 ? 87  ASP C C   1 
ATOM   2969 O O   . ASP C 1 87  ? 26.88005  23.52759 -21.41529 1.000 16.81666 ? 87  ASP C O   1 
ATOM   2970 C CB  . ASP C 1 87  ? 26.55913  23.28618 -24.69831 1.000 15.31767 ? 87  ASP C CB  1 
ATOM   2971 C CG  . ASP C 1 87  ? 26.64206  22.27225 -25.80449 1.000 14.92428 ? 87  ASP C CG  1 
ATOM   2972 O OD1 . ASP C 1 87  ? 26.52336  21.06647 -25.51493 1.000 18.48150 ? 87  ASP C OD1 1 
ATOM   2973 O OD2 . ASP C 1 87  ? 26.85527  22.70163 -26.96315 1.000 20.00451 ? 87  ASP C OD2 1 
ATOM   2974 N N   . ASP C 1 88  ? 25.24756  24.79729 -22.32176 1.000 13.45660 ? 88  ASP C N   1 
ATOM   2975 C CA  . ASP C 1 88  ? 25.47033  25.89354 -21.39519 1.000 14.81784 ? 88  ASP C CA  1 
ATOM   2976 C C   . ASP C 1 88  ? 24.85274  25.62299 -20.03289 1.000 14.52331 ? 88  ASP C C   1 
ATOM   2977 O O   . ASP C 1 88  ? 25.40778  26.05678 -19.01529 1.000 14.91649 ? 88  ASP C O   1 
ATOM   2978 C CB  . ASP C 1 88  ? 24.94445  27.20176 -21.99224 1.000 13.89029 ? 88  ASP C CB  1 
ATOM   2979 C CG  . ASP C 1 88  ? 25.78509  27.68032 -23.16859 1.000 16.98984 ? 88  ASP C CG  1 
ATOM   2980 O OD1 . ASP C 1 88  ? 26.74346  26.96751 -23.54275 1.000 22.15675 ? 88  ASP C OD1 1 
ATOM   2981 O OD2 . ASP C 1 88  ? 25.49350  28.75629 -23.72066 1.000 20.48405 ? 88  ASP C OD2 1 
ATOM   2982 N N   . VAL C 1 89  ? 23.72247  24.91123 -19.97611 1.000 12.46879 ? 89  VAL C N   1 
ATOM   2983 C CA  . VAL C 1 89  ? 23.21089  24.49594 -18.67665 1.000 15.14099 ? 89  VAL C CA  1 
ATOM   2984 C C   . VAL C 1 89  ? 24.16688  23.50562 -18.03058 1.000 17.08415 ? 89  VAL C C   1 
ATOM   2985 O O   . VAL C 1 89  ? 24.41621  23.56628 -16.82124 1.000 17.31972 ? 89  VAL C O   1 
ATOM   2986 C CB  . VAL C 1 89  ? 21.78725  23.92238 -18.81752 1.000 13.61641 ? 89  VAL C CB  1 
ATOM   2987 C CG1 . VAL C 1 89  ? 21.34851  23.19924 -17.53934 1.000 12.33772 ? 89  VAL C CG1 1 
ATOM   2988 C CG2 . VAL C 1 89  ? 20.83527  25.05287 -19.16176 1.000 11.88813 ? 89  VAL C CG2 1 
ATOM   2989 N N   . SER C 1 90  ? 24.73567  22.59563 -18.82469 1.000 14.60788 ? 90  SER C N   1 
ATOM   2990 C CA  . SER C 1 90  ? 25.71949  21.65533 -18.29074 1.000 16.11213 ? 90  SER C CA  1 
ATOM   2991 C C   . SER C 1 90  ? 26.86363  22.38597 -17.59973 1.000 16.55872 ? 90  SER C C   1 
ATOM   2992 O O   . SER C 1 90  ? 27.27620  22.01265 -16.49622 1.000 17.43576 ? 90  SER C O   1 
ATOM   2993 C CB  . SER C 1 90  ? 26.25436  20.76475 -19.40887 1.000 19.50220 ? 90  SER C CB  1 
ATOM   2994 O OG  . SER C 1 90  ? 27.26219  19.88892 -18.92655 1.000 24.58642 ? 90  SER C OG  1 
ATOM   2995 N N   . VAL C 1 91  ? 27.39261  23.42808 -18.24239 1.000 17.68370 ? 91  VAL C N   1 
ATOM   2996 C CA  . VAL C 1 91  ? 28.47309  24.20338 -17.63938 1.000 18.31733 ? 91  VAL C CA  1 
ATOM   2997 C C   . VAL C 1 91  ? 27.97531  24.94484 -16.40413 1.000 20.02015 ? 91  VAL C C   1 
ATOM   2998 O O   . VAL C 1 91  ? 28.62749  24.93800 -15.35257 1.000 17.01963 ? 91  VAL C O   1 
ATOM   2999 C CB  . VAL C 1 91  ? 29.07774  25.17338 -18.66782 1.000 21.37470 ? 91  VAL C CB  1 
ATOM   3000 C CG1 . VAL C 1 91  ? 29.98283  26.16984 -17.98180 1.000 22.44218 ? 91  VAL C CG1 1 
ATOM   3001 C CG2 . VAL C 1 91  ? 29.84709  24.40115 -19.73725 1.000 18.63599 ? 91  VAL C CG2 1 
ATOM   3002 N N   . ALA C 1 92  ? 26.80821  25.58677 -16.50637 1.000 15.10068 ? 92  ALA C N   1 
ATOM   3003 C CA  . ALA C 1 92  ? 26.35458  26.45464 -15.42029 1.000 17.70987 ? 92  ALA C CA  1 
ATOM   3004 C C   . ALA C 1 92  ? 25.97901  25.65949 -14.17584 1.000 18.66560 ? 92  ALA C C   1 
ATOM   3005 O O   . ALA C 1 92  ? 26.16005  26.14706 -13.04890 1.000 20.24053 ? 92  ALA C O   1 
ATOM   3006 C CB  . ALA C 1 92  ? 25.16682  27.30745 -15.88027 1.000 16.82297 ? 92  ALA C CB  1 
ATOM   3007 N N   . ALA C 1 93  ? 25.46611  24.44556 -14.35745 1.000 17.09245 ? 93  ALA C N   1 
ATOM   3008 C CA  . ALA C 1 93  ? 24.99434  23.60972 -13.26444 1.000 20.37025 ? 93  ALA C CA  1 
ATOM   3009 C C   . ALA C 1 93  ? 26.02089  22.57041 -12.83980 1.000 18.26089 ? 93  ALA C C   1 
ATOM   3010 O O   . ALA C 1 93  ? 25.78694  21.85597 -11.85902 1.000 21.90123 ? 93  ALA C O   1 
ATOM   3011 C CB  . ALA C 1 93  ? 23.68914  22.91313 -13.65785 1.000 19.67798 ? 93  ALA C CB  1 
ATOM   3012 N N   . GLU C 1 94  ? 27.14678  22.48169 -13.54655 1.000 16.78649 ? 94  GLU C N   1 
ATOM   3013 C CA  . GLU C 1 94  ? 28.15506  21.45121 -13.30679 1.000 19.88796 ? 94  GLU C CA  1 
ATOM   3014 C C   . GLU C 1 94  ? 27.51360  20.07140 -13.29360 1.000 23.97076 ? 94  GLU C C   1 
ATOM   3015 O O   . GLU C 1 94  ? 27.75647  19.25136 -12.40945 1.000 26.01146 ? 94  GLU C O   1 
ATOM   3016 C CB  . GLU C 1 94  ? 28.91062  21.70999 -12.00176 1.000 24.75581 ? 94  GLU C CB  1 
ATOM   3017 C CG  . GLU C 1 94  ? 29.51896  23.08760 -11.88924 1.000 28.24342 ? 94  GLU C CG  1 
ATOM   3018 C CD  . GLU C 1 94  ? 30.63717  23.13606 -10.86174 1.000 36.54195 ? 94  GLU C CD  1 
ATOM   3019 O OE1 . GLU C 1 94  ? 31.64914  22.42499 -11.02936 1.000 36.42416 ? 94  GLU C OE1 1 
ATOM   3020 O OE2 . GLU C 1 94  ? 30.48252  23.87152 -9.86772  1.000 38.91983 ? 94  GLU C OE2 1 
ATOM   3021 N N   . ILE C 1 95  ? 26.65819  19.81738 -14.27792 1.000 18.05346 ? 95  ILE C N   1 
ATOM   3022 C CA  . ILE C 1 95  ? 26.02678  18.51406 -14.41699 1.000 19.24176 ? 95  ILE C CA  1 
ATOM   3023 C C   . ILE C 1 95  ? 26.32224  18.02293 -15.82788 1.000 19.67133 ? 95  ILE C C   1 
ATOM   3024 O O   . ILE C 1 95  ? 26.23816  18.80012 -16.78508 1.000 19.12454 ? 95  ILE C O   1 
ATOM   3025 C CB  . ILE C 1 95  ? 24.51081  18.58684 -14.14366 1.000 18.17142 ? 95  ILE C CB  1 
ATOM   3026 C CG1 . ILE C 1 95  ? 24.23770  18.45403 -12.64356 1.000 21.15760 ? 95  ILE C CG1 1 
ATOM   3027 C CG2 . ILE C 1 95  ? 23.78325  17.45083 -14.80448 1.000 22.03756 ? 95  ILE C CG2 1 
ATOM   3028 C CD1 . ILE C 1 95  ? 23.00151  19.21265 -12.17018 1.000 23.33584 ? 95  ILE C CD1 1 
ATOM   3029 N N   . ASP C 1 96  ? 26.72266  16.75627 -15.94611 1.000 16.07853 ? 96  ASP C N   1 
ATOM   3030 C CA  . ASP C 1 96  ? 26.98250  16.14950 -17.25090 1.000 17.98346 ? 96  ASP C CA  1 
ATOM   3031 C C   . ASP C 1 96  ? 25.78766  16.28400 -18.18834 1.000 15.93454 ? 96  ASP C C   1 
ATOM   3032 O O   . ASP C 1 96  ? 24.63533  16.14943 -17.76701 1.000 15.84352 ? 96  ASP C O   1 
ATOM   3033 C CB  . ASP C 1 96  ? 27.30392  14.66772 -17.07997 1.000 21.27388 ? 96  ASP C CB  1 
ATOM   3034 C CG  . ASP C 1 96  ? 28.15697  14.11763 -18.20815 1.000 34.41536 ? 96  ASP C CG  1 
ATOM   3035 O OD1 . ASP C 1 96  ? 29.40076  14.09713 -18.05298 1.000 36.13651 ? 96  ASP C OD1 1 
ATOM   3036 O OD2 . ASP C 1 96  ? 27.57845  13.69747 -19.24649 1.000 31.55590 ? 96  ASP C OD2 1 
ATOM   3037 N N   . ARG C 1 97  ? 26.08338  16.48404 -19.48146 1.000 16.47802 ? 97  ARG C N   1 
ATOM   3038 C CA  . ARG C 1 97  ? 25.02488  16.63146 -20.48954 1.000 13.87880 ? 97  ARG C CA  1 
ATOM   3039 C C   . ARG C 1 97  ? 24.12148  15.40574 -20.58676 1.000 16.50419 ? 97  ARG C C   1 
ATOM   3040 O O   . ARG C 1 97  ? 22.95713  15.52223 -20.98781 1.000 13.61846 ? 97  ARG C O   1 
ATOM   3041 C CB  . ARG C 1 97  ? 25.62771  16.96802 -21.85646 1.000 17.44575 ? 97  ARG C CB  1 
ATOM   3042 C CG  . ARG C 1 97  ? 26.36905  18.30129 -21.85488 1.000 20.04035 ? 97  ARG C CG  1 
ATOM   3043 C CD  . ARG C 1 97  ? 27.05020  18.66574 -23.17428 1.000 31.00921 ? 97  ARG C CD  1 
ATOM   3044 N NE  . ARG C 1 97  ? 27.93316  17.63586 -23.69972 1.000 33.01813 ? 97  ARG C NE  1 
ATOM   3045 C CZ  . ARG C 1 97  ? 29.25041  17.65993 -23.55233 1.000 42.29437 ? 97  ARG C CZ  1 
ATOM   3046 N NH1 . ARG C 1 97  ? 29.84713  18.60487 -22.84342 1.000 42.89289 ? 97  ARG C NH1 1 
ATOM   3047 N NH2 . ARG C 1 97  ? 29.98646  16.71148 -24.12522 1.000 44.90265 ? 97  ARG C NH2 1 
ATOM   3048 N N   . LYS C 1 98  ? 24.61629  14.22480 -20.22309 1.000 16.30431 ? 98  LYS C N   1 
ATOM   3049 C CA  . LYS C 1 98  ? 23.78191  13.03096 -20.24162 1.000 13.50898 ? 98  LYS C CA  1 
ATOM   3050 C C   . LYS C 1 98  ? 22.60322  13.10046 -19.27805 1.000 15.71004 ? 98  LYS C C   1 
ATOM   3051 O O   . LYS C 1 98  ? 21.66456  12.30634 -19.41047 1.000 14.97589 ? 98  LYS C O   1 
ATOM   3052 C CB  . LYS C 1 98  ? 24.67588  11.83130 -19.94677 1.000 18.94647 ? 98  LYS C CB  1 
ATOM   3053 C CG  . LYS C 1 98  ? 25.09030  11.76176 -18.48880 1.000 22.76838 ? 98  LYS C CG  1 
ATOM   3054 C CD  . LYS C 1 98  ? 26.03012  10.59257 -18.21102 1.000 21.64395 ? 98  LYS C CD  1 
ATOM   3055 C CE  . LYS C 1 98  ? 26.48217  10.62886 -16.74513 1.000 24.70852 ? 98  LYS C CE  1 
ATOM   3056 N NZ  . LYS C 1 98  ? 27.65523  9.73690  -16.45805 1.000 29.82721 ? 98  LYS C NZ  1 
ATOM   3057 N N   . HIS C 1 99  ? 22.61570  14.03730 -18.33371 1.000 13.36264 ? 99  HIS C N   1 
ATOM   3058 C CA  . HIS C 1 99  ? 21.51544  14.20981 -17.40172 1.000 13.22079 ? 99  HIS C CA  1 
ATOM   3059 C C   . HIS C 1 99  ? 20.45467  15.17925 -17.89943 1.000 12.06245 ? 99  HIS C C   1 
ATOM   3060 O O   . HIS C 1 99  ? 19.45716  15.38031 -17.19979 1.000 12.66157 ? 99  HIS C O   1 
ATOM   3061 C CB  . HIS C 1 99  ? 22.03854  14.72147 -16.06394 1.000 15.91121 ? 99  HIS C CB  1 
ATOM   3062 C CG  . HIS C 1 99  ? 22.83571  13.71642 -15.30381 1.000 19.62316 ? 99  HIS C CG  1 
ATOM   3063 N ND1 . HIS C 1 99  ? 22.29003  12.55020 -14.81075 1.000 17.79834 ? 99  HIS C ND1 1 
ATOM   3064 C CD2 . HIS C 1 99  ? 24.13612  13.71760 -14.92702 1.000 22.98762 ? 99  HIS C CD2 1 
ATOM   3065 C CE1 . HIS C 1 99  ? 23.22829  11.86711 -14.17527 1.000 19.14500 ? 99  HIS C CE1 1 
ATOM   3066 N NE2 . HIS C 1 99  ? 24.35481  12.55727 -14.22697 1.000 18.54444 ? 99  HIS C NE2 1 
ATOM   3067 N N   . ILE C 1 100 ? 20.64017  15.78544 -19.06896 1.000 12.10594 ? 100 ILE C N   1 
ATOM   3068 C CA  . ILE C 1 100 ? 19.87392  16.96693 -19.46657 1.000 10.40294 ? 100 ILE C CA  1 
ATOM   3069 C C   . ILE C 1 100 ? 18.93567  16.60902 -20.61395 1.000 12.64069 ? 100 ILE C C   1 
ATOM   3070 O O   . ILE C 1 100 ? 19.37362  16.16163 -21.68174 1.000 12.22318 ? 100 ILE C O   1 
ATOM   3071 C CB  . ILE C 1 100 ? 20.78988  18.12900 -19.86930 1.000 11.05841 ? 100 ILE C CB  1 
ATOM   3072 C CG1 . ILE C 1 100 ? 21.80257  18.45407 -18.76827 1.000 11.37599 ? 100 ILE C CG1 1 
ATOM   3073 C CG2 . ILE C 1 100 ? 19.94559  19.35729 -20.21728 1.000 12.56259 ? 100 ILE C CG2 1 
ATOM   3074 C CD1 . ILE C 1 100 ? 22.76269  19.55579 -19.14015 1.000 13.26678 ? 100 ILE C CD1 1 
ATOM   3075 N N   . TRP C 1 101 ? 17.65126  16.87630 -20.41300 1.000 11.13766 ? 101 TRP C N   1 
ATOM   3076 C CA  . TRP C 1 101 ? 16.61604  16.66281 -21.41276 1.000 9.47320  ? 101 TRP C CA  1 
ATOM   3077 C C   . TRP C 1 101 ? 16.00359  18.01893 -21.73474 1.000 10.11549 ? 101 TRP C C   1 
ATOM   3078 O O   . TRP C 1 101 ? 15.80770  18.83712 -20.83380 1.000 9.95099  ? 101 TRP C O   1 
ATOM   3079 C CB  . TRP C 1 101 ? 15.53778  15.71355 -20.88748 1.000 10.79066 ? 101 TRP C CB  1 
ATOM   3080 C CG  . TRP C 1 101 ? 15.99182  14.33943 -20.45617 1.000 12.48191 ? 101 TRP C CG  1 
ATOM   3081 C CD1 . TRP C 1 101 ? 17.10748  14.01155 -19.71558 1.000 15.74614 ? 101 TRP C CD1 1 
ATOM   3082 C CD2 . TRP C 1 101 ? 15.32839  13.10546 -20.74261 1.000 12.08740 ? 101 TRP C CD2 1 
ATOM   3083 N NE1 . TRP C 1 101 ? 17.16012  12.64485 -19.52805 1.000 13.49386 ? 101 TRP C NE1 1 
ATOM   3084 C CE2 . TRP C 1 101 ? 16.07757  12.07056 -20.14426 1.000 14.07413 ? 101 TRP C CE2 1 
ATOM   3085 C CE3 . TRP C 1 101 ? 14.15627  12.77535 -21.44210 1.000 10.95506 ? 101 TRP C CE3 1 
ATOM   3086 C CZ2 . TRP C 1 101 ? 15.70068  10.72463 -20.23550 1.000 13.47484 ? 101 TRP C CZ2 1 
ATOM   3087 C CZ3 . TRP C 1 101 ? 13.78139  11.44535 -21.53127 1.000 15.40532 ? 101 TRP C CZ3 1 
ATOM   3088 C CH2 . TRP C 1 101 ? 14.55732  10.42983 -20.92580 1.000 14.77035 ? 101 TRP C CH2 1 
ATOM   3089 N N   . VAL C 1 102 ? 15.71774  18.27563 -23.01497 1.000 9.55376  ? 102 VAL C N   1 
ATOM   3090 C CA  . VAL C 1 102 ? 15.24816  19.59447 -23.45177 1.000 7.57529  ? 102 VAL C CA  1 
ATOM   3091 C C   . VAL C 1 102 ? 14.19792  19.38663 -24.53203 1.000 11.02218 ? 102 VAL C C   1 
ATOM   3092 O O   . VAL C 1 102 ? 14.51980  18.87804 -25.60992 1.000 10.14659 ? 102 VAL C O   1 
ATOM   3093 C CB  . VAL C 1 102 ? 16.38264  20.48248 -24.00652 1.000 9.14859  ? 102 VAL C CB  1 
ATOM   3094 C CG1 . VAL C 1 102 ? 15.82299  21.83920 -24.42929 1.000 10.55202 ? 102 VAL C CG1 1 
ATOM   3095 C CG2 . VAL C 1 102 ? 17.47360  20.69265 -22.96801 1.000 8.13174  ? 102 VAL C CG2 1 
ATOM   3096 N N   . TYR C 1 103 ? 12.94970  19.77489 -24.25301 1.000 10.00127 ? 103 TYR C N   1 
ATOM   3097 C CA  . TYR C 1 103 ? 11.86112  19.68337 -25.22067 1.000 8.78345  ? 103 TYR C CA  1 
ATOM   3098 C C   . TYR C 1 103 ? 11.30705  21.07485 -25.46947 1.000 8.36417  ? 103 TYR C C   1 
ATOM   3099 O O   . TYR C 1 103 ? 11.01998  21.79807 -24.51321 1.000 9.24334  ? 103 TYR C O   1 
ATOM   3100 C CB  . TYR C 1 103 ? 10.70081  18.81434 -24.72313 1.000 9.80311  ? 103 TYR C CB  1 
ATOM   3101 C CG  . TYR C 1 103 ? 10.94100  17.33440 -24.59866 1.000 10.01440 ? 103 TYR C CG  1 
ATOM   3102 C CD1 . TYR C 1 103 ? 12.18317  16.76464 -24.91430 1.000 9.95277  ? 103 TYR C CD1 1 
ATOM   3103 C CD2 . TYR C 1 103 ? 9.91727   16.49331 -24.17868 1.000 12.26638 ? 103 TYR C CD2 1 
ATOM   3104 C CE1 . TYR C 1 103 ? 12.38940  15.38570 -24.78262 1.000 11.02037 ? 103 TYR C CE1 1 
ATOM   3105 C CE2 . TYR C 1 103 ? 10.11462  15.12227 -24.05701 1.000 15.26235 ? 103 TYR C CE2 1 
ATOM   3106 C CZ  . TYR C 1 103 ? 11.35240  14.57993 -24.35828 1.000 11.31329 ? 103 TYR C CZ  1 
ATOM   3107 O OH  . TYR C 1 103 ? 11.52129  13.21467 -24.23826 1.000 11.14769 ? 103 TYR C OH  1 
ATOM   3108 N N   . PHE C 1 104 ? 11.11440  21.43465 -26.73401 1.000 9.29756  ? 104 PHE C N   1 
ATOM   3109 C CA  . PHE C 1 104 ? 10.49533  22.70037 -27.09699 1.000 7.17963  ? 104 PHE C CA  1 
ATOM   3110 C C   . PHE C 1 104 ? 9.07906   22.46398 -27.60154 1.000 8.55009  ? 104 PHE C C   1 
ATOM   3111 O O   . PHE C 1 104 ? 8.87664   21.71789 -28.56491 1.000 10.46795 ? 104 PHE C O   1 
ATOM   3112 C CB  . PHE C 1 104 ? 11.28384  23.42593 -28.19342 1.000 11.14410 ? 104 PHE C CB  1 
ATOM   3113 C CG  . PHE C 1 104 ? 12.65799  23.94016 -27.77076 1.000 10.33106 ? 104 PHE C CG  1 
ATOM   3114 C CD1 . PHE C 1 104 ? 13.04071  24.04589 -26.43606 1.000 8.45045  ? 104 PHE C CD1 1 
ATOM   3115 C CD2 . PHE C 1 104 ? 13.55188  24.34817 -28.74836 1.000 11.45171 ? 104 PHE C CD2 1 
ATOM   3116 C CE1 . PHE C 1 104 ? 14.30154  24.53517 -26.11110 1.000 8.38145  ? 104 PHE C CE1 1 
ATOM   3117 C CE2 . PHE C 1 104 ? 14.80962  24.83965 -28.42488 1.000 11.64526 ? 104 PHE C CE2 1 
ATOM   3118 C CZ  . PHE C 1 104 ? 15.17703  24.94205 -27.09711 1.000 10.09351 ? 104 PHE C CZ  1 
ATOM   3119 N N   . GLY C 1 105 ? 8.10979   23.14227 -26.99845 1.000 7.44876  ? 105 GLY C N   1 
ATOM   3120 C CA  . GLY C 1 105 ? 6.75458   23.20092 -27.52998 1.000 11.93511 ? 105 GLY C CA  1 
ATOM   3121 C C   . GLY C 1 105 ? 6.47812   24.56480 -28.13365 1.000 11.42319 ? 105 GLY C C   1 
ATOM   3122 O O   . GLY C 1 105 ? 7.05509   25.56336 -27.70518 1.000 12.07450 ? 105 GLY C O   1 
ATOM   3123 N N   . GLU C 1 106 ? 5.60962   24.60945 -29.16011 1.000 8.56678  ? 106 GLU C N   1 
ATOM   3124 C CA  . GLU C 1 106 ? 5.31465   25.87651 -29.82742 1.000 7.86816  ? 106 GLU C CA  1 
ATOM   3125 C C   . GLU C 1 106 ? 3.81445   26.10294 -29.93378 1.000 9.06718  ? 106 GLU C C   1 
ATOM   3126 O O   . GLU C 1 106 ? 3.03725   25.16412 -30.14239 1.000 10.43453 ? 106 GLU C O   1 
ATOM   3127 C CB  . GLU C 1 106 ? 5.90099   25.95464 -31.24506 1.000 11.56156 ? 106 GLU C CB  1 
ATOM   3128 C CG  . GLU C 1 106 ? 7.40155   25.69361 -31.38462 1.000 9.34545  ? 106 GLU C CG  1 
ATOM   3129 C CD  . GLU C 1 106 ? 7.72626   25.19531 -32.78961 1.000 10.72460 ? 106 GLU C CD  1 
ATOM   3130 O OE1 . GLU C 1 106 ? 7.54474   23.98745 -33.05224 1.000 11.98169 ? 106 GLU C OE1 1 
ATOM   3131 O OE2 . GLU C 1 106 ? 8.16632   26.01402 -33.62042 1.000 11.86095 ? 106 GLU C OE2 1 
ATOM   3132 N N   . MET C 1 107 ? 3.42083   27.36867 -29.81453 1.000 7.65237  ? 107 MET C N   1 
ATOM   3133 C CA  . MET C 1 107 ? 2.03597   27.81820 -29.92917 1.000 8.09861  ? 107 MET C CA  1 
ATOM   3134 C C   . MET C 1 107 ? 1.95734   29.09199 -30.75804 1.000 7.44935  ? 107 MET C C   1 
ATOM   3135 O O   . MET C 1 107 ? 2.93781   29.84364 -30.85143 1.000 7.80068  ? 107 MET C O   1 
ATOM   3136 C CB  . MET C 1 107 ? 1.40039   28.05660 -28.54209 1.000 9.44924  ? 107 MET C CB  1 
ATOM   3137 C CG  . MET C 1 107 ? 1.55612   26.87427 -27.61788 1.000 7.94353  ? 107 MET C CG  1 
ATOM   3138 S SD  . MET C 1 107 ? 1.61103   27.34016 -25.88366 1.000 11.67477 ? 107 MET C SD  1 
ATOM   3139 C CE  . MET C 1 107 ? 3.39640   27.36021 -25.73608 1.000 13.98725 ? 107 MET C CE  1 
ATOM   3140 N N   . PRO C 1 108 ? 0.80299   29.35750 -31.38228 1.000 8.20834  ? 108 PRO C N   1 
ATOM   3141 C CA  . PRO C 1 108 ? 0.62738   30.64314 -32.06263 1.000 9.12765  ? 108 PRO C CA  1 
ATOM   3142 C C   . PRO C 1 108 ? 0.79129   31.77709 -31.07477 1.000 10.27699 ? 108 PRO C C   1 
ATOM   3143 O O   . PRO C 1 108 ? 0.28273   31.72023 -29.95357 1.000 9.93006  ? 108 PRO C O   1 
ATOM   3144 C CB  . PRO C 1 108 ? -0.80626  30.57217 -32.60058 1.000 10.56461 ? 108 PRO C CB  1 
ATOM   3145 C CG  . PRO C 1 108 ? -1.12815  29.11206 -32.67038 1.000 12.80919 ? 108 PRO C CG  1 
ATOM   3146 C CD  . PRO C 1 108 ? -0.36728  28.47354 -31.54040 1.000 10.30553 ? 108 PRO C CD  1 
ATOM   3147 N N   . ALA C 1 109 ? 1.52502   32.80120 -31.49363 1.000 9.04829  ? 109 ALA C N   1 
ATOM   3148 C CA  . ALA C 1 109 ? 1.71700   33.95296 -30.62380 1.000 9.26460  ? 109 ALA C CA  1 
ATOM   3149 C C   . ALA C 1 109 ? 0.37899   34.54775 -30.19744 1.000 12.11489 ? 109 ALA C C   1 
ATOM   3150 O O   . ALA C 1 109 ? 0.28602   35.13274 -29.11568 1.000 10.21937 ? 109 ALA C O   1 
ATOM   3151 C CB  . ALA C 1 109 ? 2.58163   35.00220 -31.32070 1.000 13.24191 ? 109 ALA C CB  1 
ATOM   3152 N N   . GLN C 1 110 ? -0.67374  34.35224 -31.00427 1.000 12.30232 ? 110 GLN C N   1 
ATOM   3153 C CA  . GLN C 1 110 ? -1.97193  34.95179 -30.70480 1.000 12.24387 ? 110 GLN C CA  1 
ATOM   3154 C C   . GLN C 1 110 ? -2.63155  34.35632 -29.46461 1.000 12.85667 ? 110 GLN C C   1 
ATOM   3155 O O   . GLN C 1 110 ? -3.57226  34.95722 -28.92793 1.000 10.73110 ? 110 GLN C O   1 
ATOM   3156 C CB  . GLN C 1 110 ? -2.90458  34.81304 -31.91313 1.000 12.88751 ? 110 GLN C CB  1 
ATOM   3157 C CG  . GLN C 1 110 ? -2.51777  35.71620 -33.09092 1.000 15.83204 ? 110 GLN C CG  1 
ATOM   3158 C CD  . GLN C 1 110 ? -1.33860  35.17162 -33.92573 1.000 27.02445 ? 110 GLN C CD  1 
ATOM   3159 O OE1 . GLN C 1 110 ? -0.92102  34.00531 -33.79006 1.000 22.39387 ? 110 GLN C OE1 1 
ATOM   3160 N NE2 . GLN C 1 110 ? -0.78520  36.03073 -34.77890 1.000 29.83474 ? 110 GLN C NE2 1 
ATOM   3161 N N   . GLN C 1 111 ? -2.15719  33.21216 -28.97591 1.000 8.94287  ? 111 GLN C N   1 
ATOM   3162 C CA  . GLN C 1 111 ? -2.66860  32.64494 -27.73266 1.000 9.59761  ? 111 GLN C CA  1 
ATOM   3163 C C   . GLN C 1 111 ? -1.57389  32.58888 -26.67431 1.000 10.05750 ? 111 GLN C C   1 
ATOM   3164 O O   . GLN C 1 111 ? -1.57482  31.70490 -25.81249 1.000 9.13376  ? 111 GLN C O   1 
ATOM   3165 C CB  . GLN C 1 111 ? -3.28359  31.26621 -27.96926 1.000 11.61854 ? 111 GLN C CB  1 
ATOM   3166 C CG  . GLN C 1 111 ? -2.30271  30.19426 -28.46733 1.000 9.45233  ? 111 GLN C CG  1 
ATOM   3167 C CD  . GLN C 1 111 ? -3.03552  29.08837 -29.20140 1.000 10.76892 ? 111 GLN C CD  1 
ATOM   3168 O OE1 . GLN C 1 111 ? -3.74045  29.34565 -30.17462 1.000 11.46732 ? 111 GLN C OE1 1 
ATOM   3169 N NE2 . GLN C 1 111 ? -2.81443  27.85487 -28.78860 1.000 8.99144  ? 111 GLN C NE2 1 
ATOM   3170 N N   . MET C 1 112 ? -0.64081  33.54280 -26.73582 1.000 10.09399 ? 112 MET C N   1 
ATOM   3171 C CA  . MET C 1 112 ? 0.42008   33.68119 -25.74385 1.000 8.86147  ? 112 MET C CA  1 
ATOM   3172 C C   . MET C 1 112 ? 0.52438   35.10031 -25.19792 1.000 8.37815  ? 112 MET C C   1 
ATOM   3173 O O   . MET C 1 112 ? 0.66122   36.06953 -25.95581 1.000 9.71030  ? 112 MET C O   1 
ATOM   3174 C CB  . MET C 1 112 ? 1.78534   33.21940 -26.25822 1.000 9.51743  ? 112 MET C CB  1 
ATOM   3175 C CG  . MET C 1 112 ? 1.82339   31.75867 -26.66993 1.000 9.68112  ? 112 MET C CG  1 
ATOM   3176 S SD  . MET C 1 112 ? 3.22827   31.35241 -27.72244 1.000 10.56554 ? 112 MET C SD  1 
ATOM   3177 C CE  . MET C 1 112 ? 4.45215   31.32185 -26.44997 1.000 10.00744 ? 112 MET C CE  1 
ATOM   3178 N N   . VAL C 1 113 ? 0.51522   35.19321 -23.86814 1.000 7.46440  ? 113 VAL C N   1 
ATOM   3179 C CA  . VAL C 1 113 ? 0.52617   36.45025 -23.12337 1.000 7.87705  ? 113 VAL C CA  1 
ATOM   3180 C C   . VAL C 1 113 ? 1.74247   36.44928 -22.20296 1.000 8.62195  ? 113 VAL C C   1 
ATOM   3181 O O   . VAL C 1 113 ? 1.87599   35.55158 -21.36063 1.000 7.68608  ? 113 VAL C O   1 
ATOM   3182 C CB  . VAL C 1 113 ? -0.76889  36.60740 -22.30816 1.000 6.22226  ? 113 VAL C CB  1 
ATOM   3183 C CG1 . VAL C 1 113 ? -0.65124  37.76871 -21.29129 1.000 10.19170 ? 113 VAL C CG1 1 
ATOM   3184 C CG2 . VAL C 1 113 ? -1.96922  36.78716 -23.24243 1.000 9.11546  ? 113 VAL C CG2 1 
ATOM   3185 N N   . ASP C 1 114 ? 2.63478   37.43559 -22.37327 1.000 7.59705  ? 114 ASP C N   1 
ATOM   3186 C CA  . ASP C 1 114 ? 3.71678   37.71828 -21.42772 1.000 9.80769  ? 114 ASP C CA  1 
ATOM   3187 C C   . ASP C 1 114 ? 3.44952   39.07514 -20.79854 1.000 8.88997  ? 114 ASP C C   1 
ATOM   3188 O O   . ASP C 1 114 ? 3.07531   40.01659 -21.50096 1.000 9.81586  ? 114 ASP C O   1 
ATOM   3189 C CB  . ASP C 1 114 ? 5.11480   37.79893 -22.06983 1.000 10.95049 ? 114 ASP C CB  1 
ATOM   3190 C CG  . ASP C 1 114 ? 5.59326   36.50221 -22.68903 1.000 11.03558 ? 114 ASP C CG  1 
ATOM   3191 O OD1 . ASP C 1 114 ? 4.89435   35.46827 -22.64452 1.000 9.66799  ? 114 ASP C OD1 1 
ATOM   3192 O OD2 . ASP C 1 114 ? 6.73567   36.53336 -23.18795 1.000 12.42999 ? 114 ASP C OD2 1 
ATOM   3193 N N   . TYR C 1 115 ? 3.65826   39.18527 -19.48253 1.000 9.37923  ? 115 TYR C N   1 
ATOM   3194 C CA  . TYR C 1 115 ? 3.47419   40.46623 -18.78261 1.000 10.71142 ? 115 TYR C CA  1 
ATOM   3195 C C   . TYR C 1 115 ? 2.09575   41.06425 -19.06533 1.000 10.51482 ? 115 TYR C C   1 
ATOM   3196 O O   . TYR C 1 115 ? 1.95017   42.27768 -19.21498 1.000 11.13092 ? 115 TYR C O   1 
ATOM   3197 C CB  . TYR C 1 115 ? 4.54382   41.49641 -19.16790 1.000 12.22847 ? 115 TYR C CB  1 
ATOM   3198 C CG  . TYR C 1 115 ? 5.97446   41.22118 -18.77585 1.000 10.32652 ? 115 TYR C CG  1 
ATOM   3199 C CD1 . TYR C 1 115 ? 6.45557   41.59023 -17.53456 1.000 12.09501 ? 115 TYR C CD1 1 
ATOM   3200 C CD2 . TYR C 1 115 ? 6.85904   40.65124 -19.68877 1.000 13.45577 ? 115 TYR C CD2 1 
ATOM   3201 C CE1 . TYR C 1 115 ? 7.77327   41.38722 -17.19671 1.000 11.98527 ? 115 TYR C CE1 1 
ATOM   3202 C CE2 . TYR C 1 115 ? 8.18259   40.42863 -19.34781 1.000 11.55109 ? 115 TYR C CE2 1 
ATOM   3203 C CZ  . TYR C 1 115 ? 8.62408   40.80585 -18.10626 1.000 10.82690 ? 115 TYR C CZ  1 
ATOM   3204 O OH  . TYR C 1 115 ? 9.92379   40.59481 -17.75531 1.000 11.95972 ? 115 TYR C OH  1 
ATOM   3205 N N   . GLY C 1 116 ? 1.07694   40.21795 -19.21190 1.000 8.34054  ? 116 GLY C N   1 
ATOM   3206 C CA  . GLY C 1 116 ? -0.26963  40.71855 -19.42822 1.000 8.27375  ? 116 GLY C CA  1 
ATOM   3207 C C   . GLY C 1 116 ? -0.60776  41.11301 -20.85438 1.000 9.14767  ? 116 GLY C C   1 
ATOM   3208 O O   . GLY C 1 116 ? -1.75568  41.50038 -21.11226 1.000 10.53341 ? 116 GLY C O   1 
ATOM   3209 N N   . ARG C 1 117 ? 0.32880   40.99636 -21.78857 1.000 9.44458  ? 117 ARG C N   1 
ATOM   3210 C CA  . ARG C 1 117 ? 0.14743   41.42938 -23.16716 1.000 9.48732  ? 117 ARG C CA  1 
ATOM   3211 C C   . ARG C 1 117 ? 0.37159   40.27408 -24.13492 1.000 10.09001 ? 117 ARG C C   1 
ATOM   3212 O O   . ARG C 1 117 ? 1.24859   39.42412 -23.92733 1.000 9.83670  ? 117 ARG C O   1 
ATOM   3213 C CB  . ARG C 1 117 ? 1.11022   42.57688 -23.54170 1.000 10.20568 ? 117 ARG C CB  1 
ATOM   3214 C CG  . ARG C 1 117 ? 0.95463   43.83937 -22.70386 1.000 11.32912 ? 117 ARG C CG  1 
ATOM   3215 C CD  . ARG C 1 117 ? -0.47757  44.35827 -22.75432 1.000 17.52023 ? 117 ARG C CD  1 
ATOM   3216 N NE  . ARG C 1 117 ? -0.80654  44.93532 -24.04908 1.000 23.26278 ? 117 ARG C NE  1 
ATOM   3217 C CZ  . ARG C 1 117 ? -0.44712  46.14974 -24.44822 1.000 30.30734 ? 117 ARG C CZ  1 
ATOM   3218 N NH1 . ARG C 1 117 ? 0.22416   46.96672 -23.65705 1.000 23.32811 ? 117 ARG C NH1 1 
ATOM   3219 N NH2 . ARG C 1 117 ? -0.78636  46.55981 -25.66758 1.000 28.39435 ? 117 ARG C NH2 1 
ATOM   3220 N N   . PHE C 1 118 ? -0.38038  40.27983 -25.23318 1.000 9.21273  ? 118 PHE C N   1 
ATOM   3221 C CA  . PHE C 1 118 ? -0.16628  39.27160 -26.25869 1.000 8.85317  ? 118 PHE C CA  1 
ATOM   3222 C C   . PHE C 1 118 ? 1.14927   39.50671 -26.98672 1.000 9.72558  ? 118 PHE C C   1 
ATOM   3223 O O   . PHE C 1 118 ? 1.49596   40.64031 -27.33829 1.000 11.36948 ? 118 PHE C O   1 
ATOM   3224 C CB  . PHE C 1 118 ? -1.32200  39.26828 -27.25406 1.000 11.44662 ? 118 PHE C CB  1 
ATOM   3225 C CG  . PHE C 1 118 ? -2.58464  38.68063 -26.69547 1.000 11.30246 ? 118 PHE C CG  1 
ATOM   3226 C CD1 . PHE C 1 118 ? -3.49479  39.47198 -26.01480 1.000 12.83193 ? 118 PHE C CD1 1 
ATOM   3227 C CD2 . PHE C 1 118 ? -2.83771  37.33313 -26.81148 1.000 10.28277 ? 118 PHE C CD2 1 
ATOM   3228 C CE1 . PHE C 1 118 ? -4.64585  38.92335 -25.49186 1.000 15.86564 ? 118 PHE C CE1 1 
ATOM   3229 C CE2 . PHE C 1 118 ? -3.98944  36.77778 -26.28753 1.000 12.12616 ? 118 PHE C CE2 1 
ATOM   3230 C CZ  . PHE C 1 118 ? -4.89328  37.57267 -25.63386 1.000 12.37054 ? 118 PHE C CZ  1 
ATOM   3231 N N   . LEU C 1 119 ? 1.85520   38.41852 -27.26032 1.000 10.72645 ? 119 LEU C N   1 
ATOM   3232 C CA  . LEU C 1 119 ? 3.15440   38.49740 -27.90788 1.000 9.74794  ? 119 LEU C CA  1 
ATOM   3233 C C   . LEU C 1 119 ? 3.01705   38.85190 -29.38609 1.000 12.18173 ? 119 LEU C C   1 
ATOM   3234 O O   . LEU C 1 119 ? 1.97155   38.60841 -29.99923 1.000 13.82579 ? 119 LEU C O   1 
ATOM   3235 C CB  . LEU C 1 119 ? 3.87694   37.15894 -27.76964 1.000 10.14502 ? 119 LEU C CB  1 
ATOM   3236 C CG  . LEU C 1 119 ? 4.44095   36.90603 -26.37726 1.000 11.47814 ? 119 LEU C CG  1 
ATOM   3237 C CD1 . LEU C 1 119 ? 4.96275   35.48106 -26.31505 1.000 11.05462 ? 119 LEU C CD1 1 
ATOM   3238 C CD2 . LEU C 1 119 ? 5.56306   37.91489 -26.09734 1.000 13.15788 ? 119 LEU C CD2 1 
ATOM   3239 N N   . PRO C 1 120 ? 4.08802   39.41943 -29.98663 1.000 12.10082 ? 120 PRO C N   1 
ATOM   3240 C CA  . PRO C 1 120 ? 4.10829   39.63245 -31.43404 1.000 14.92425 ? 120 PRO C CA  1 
ATOM   3241 C C   . PRO C 1 120 ? 4.64740   38.40546 -32.14313 1.000 16.11499 ? 120 PRO C C   1 
ATOM   3242 O O   . PRO C 1 120 ? 5.07347   37.44830 -31.48717 1.000 14.68519 ? 120 PRO C O   1 
ATOM   3243 C CB  . PRO C 1 120 ? 5.08056   40.80684 -31.59139 1.000 13.65666 ? 120 PRO C CB  1 
ATOM   3244 C CG  . PRO C 1 120 ? 6.03973   40.64920 -30.40950 1.000 14.83264 ? 120 PRO C CG  1 
ATOM   3245 C CD  . PRO C 1 120 ? 5.40131   39.73103 -29.39184 1.000 12.87244 ? 120 PRO C CD  1 
ATOM   3246 N N   . GLN C 1 121 ? 4.70062   38.43120 -33.46849 1.000 20.45620 ? 121 GLN C N   1 
ATOM   3247 C CA  . GLN C 1 121 ? 5.36490   37.33861 -34.15362 1.000 19.68960 ? 121 GLN C CA  1 
ATOM   3248 C C   . GLN C 1 121 ? 6.87938   37.41763 -33.96250 1.000 17.63043 ? 121 GLN C C   1 
ATOM   3249 O O   . GLN C 1 121 ? 7.43060   38.49008 -33.68979 1.000 14.69016 ? 121 GLN C O   1 
ATOM   3250 C CB  . GLN C 1 121 ? 5.01310   37.31653 -35.64020 1.000 18.99214 ? 121 GLN C CB  1 
ATOM   3251 C CG  . GLN C 1 121 ? 3.52385   37.30418 -35.88839 1.000 17.68406 ? 121 GLN C CG  1 
ATOM   3252 C CD  . GLN C 1 121 ? 2.90269   35.93618 -35.60475 1.000 25.45371 ? 121 GLN C CD  1 
ATOM   3253 O OE1 . GLN C 1 121 ? 1.68264   35.80293 -35.51748 1.000 32.09084 ? 121 GLN C OE1 1 
ATOM   3254 N NE2 . GLN C 1 121 ? 3.74472   34.92346 -35.42105 1.000 22.56749 ? 121 GLN C NE2 1 
ATOM   3255 N N   . PRO C 1 122 ? 7.56995   36.28149 -34.07501 1.000 15.09400 ? 122 PRO C N   1 
ATOM   3256 C CA  . PRO C 1 122 ? 9.02047   36.28173 -33.86217 1.000 16.53490 ? 122 PRO C CA  1 
ATOM   3257 C C   . PRO C 1 122 ? 9.70393   37.28473 -34.78304 1.000 21.03341 ? 122 PRO C C   1 
ATOM   3258 O O   . PRO C 1 122 ? 9.36196   37.41120 -35.96038 1.000 20.14835 ? 122 PRO C O   1 
ATOM   3259 C CB  . PRO C 1 122 ? 9.43443   34.83812 -34.17359 1.000 14.78077 ? 122 PRO C CB  1 
ATOM   3260 C CG  . PRO C 1 122 ? 8.18190   34.01157 -34.16347 1.000 17.90845 ? 122 PRO C CG  1 
ATOM   3261 C CD  . PRO C 1 122 ? 6.98833   34.92854 -34.18221 1.000 12.88562 ? 122 PRO C CD  1 
ATOM   3262 N N   . GLY C 1 123 ? 10.65114  38.02740 -34.21882 1.000 21.88713 ? 123 GLY C N   1 
ATOM   3263 C CA  . GLY C 1 123 ? 11.37881  39.04010 -34.94619 1.000 23.50989 ? 123 GLY C CA  1 
ATOM   3264 C C   . GLY C 1 123 ? 10.78660  40.42850 -34.85839 1.000 21.42112 ? 123 GLY C C   1 
ATOM   3265 O O   . GLY C 1 123 ? 11.47076  41.40047 -35.21636 1.000 23.69608 ? 123 GLY C O   1 
ATOM   3266 N N   . HIS C 1 124 ? 9.54024   40.54927 -34.39193 1.000 21.44604 ? 124 HIS C N   1 
ATOM   3267 C CA  . HIS C 1 124 ? 8.82752   41.81308 -34.27136 1.000 21.58217 ? 124 HIS C CA  1 
ATOM   3268 C C   . HIS C 1 124 ? 8.84028   42.35714 -32.84654 1.000 19.06194 ? 124 HIS C C   1 
ATOM   3269 O O   . HIS C 1 124 ? 8.00495   43.20339 -32.50919 1.000 19.47934 ? 124 HIS C O   1 
ATOM   3270 C CB  . HIS C 1 124 ? 7.37676   41.64863 -34.73113 1.000 26.72334 ? 124 HIS C CB  1 
ATOM   3271 C CG  . HIS C 1 124 ? 7.17665   41.85130 -36.19798 1.000 36.13359 ? 124 HIS C CG  1 
ATOM   3272 N ND1 . HIS C 1 124 ? 8.14777   41.55399 -37.12948 1.000 39.86964 ? 124 HIS C ND1 1 
ATOM   3273 C CD2 . HIS C 1 124 ? 6.11627   42.32228 -36.89592 1.000 40.86226 ? 124 HIS C CD2 1 
ATOM   3274 C CE1 . HIS C 1 124 ? 7.69503   41.83273 -38.33874 1.000 39.31994 ? 124 HIS C CE1 1 
ATOM   3275 N NE2 . HIS C 1 124 ? 6.46499   42.30094 -38.22507 1.000 48.12740 ? 124 HIS C NE2 1 
ATOM   3276 N N   . GLU C 1 125 ? 9.77745   41.90220 -32.00833 1.000 15.21741 ? 125 GLU C N   1 
ATOM   3277 C CA  . GLU C 1 125 ? 9.75497   42.28126 -30.59562 1.000 17.98019 ? 125 GLU C CA  1 
ATOM   3278 C C   . GLU C 1 125 ? 10.09172  43.75142 -30.37719 1.000 18.57354 ? 125 GLU C C   1 
ATOM   3279 O O   . GLU C 1 125 ? 9.62647   44.34860 -29.39854 1.000 17.08100 ? 125 GLU C O   1 
ATOM   3280 C CB  . GLU C 1 125 ? 10.72417  41.41392 -29.79150 1.000 16.74901 ? 125 GLU C CB  1 
ATOM   3281 C CG  . GLU C 1 125 ? 10.39677  39.92517 -29.77551 1.000 18.35132 ? 125 GLU C CG  1 
ATOM   3282 C CD  . GLU C 1 125 ? 10.80170  39.22036 -31.06240 1.000 21.26379 ? 125 GLU C CD  1 
ATOM   3283 O OE1 . GLU C 1 125 ? 11.52916  39.83298 -31.87949 1.000 20.03036 ? 125 GLU C OE1 1 
ATOM   3284 O OE2 . GLU C 1 125 ? 10.40630  38.05478 -31.24850 1.000 18.79365 ? 125 GLU C OE2 1 
ATOM   3285 N N   . GLY C 1 126 ? 10.91330  44.34329 -31.24523 1.000 20.32188 ? 126 GLY C N   1 
ATOM   3286 C CA  . GLY C 1 126 ? 11.31793  45.72314 -31.03145 1.000 18.13569 ? 126 GLY C CA  1 
ATOM   3287 C C   . GLY C 1 126 ? 10.15804  46.69664 -31.12935 1.000 17.25368 ? 126 GLY C C   1 
ATOM   3288 O O   . GLY C 1 126 ? 9.93608   47.51228 -30.22895 1.000 21.81800 ? 126 GLY C O   1 
ATOM   3289 N N   . GLU C 1 127 ? 9.39079   46.61626 -32.21308 1.000 20.63245 ? 127 GLU C N   1 
ATOM   3290 C CA  . GLU C 1 127 ? 8.29150   47.56009 -32.36608 1.000 22.21301 ? 127 GLU C CA  1 
ATOM   3291 C C   . GLU C 1 127 ? 7.12770   47.22625 -31.44108 1.000 23.04567 ? 127 GLU C C   1 
ATOM   3292 O O   . GLU C 1 127 ? 6.44480   48.14182 -30.96483 1.000 21.75526 ? 127 GLU C O   1 
ATOM   3293 C CB  . GLU C 1 127 ? 7.86611   47.62702 -33.83534 1.000 30.88700 ? 127 GLU C CB  1 
ATOM   3294 C CG  . GLU C 1 127 ? 7.42342   46.33247 -34.46997 1.000 32.56764 ? 127 GLU C CG  1 
ATOM   3295 C CD  . GLU C 1 127 ? 5.95201   46.33012 -34.81392 1.000 42.18119 ? 127 GLU C CD  1 
ATOM   3296 O OE1 . GLU C 1 127 ? 5.20281   47.15734 -34.24729 1.000 45.26099 ? 127 GLU C OE1 1 
ATOM   3297 O OE2 . GLU C 1 127 ? 5.55324   45.51974 -35.68121 1.000 45.28431 ? 127 GLU C OE2 1 
ATOM   3298 N N   . TRP C 1 128 ? 6.92146   45.93905 -31.13933 1.000 21.74559 ? 128 TRP C N   1 
ATOM   3299 C CA  . TRP C 1 128 ? 5.97228   45.54843 -30.09611 1.000 18.51938 ? 128 TRP C CA  1 
ATOM   3300 C C   . TRP C 1 128 ? 6.29090   46.23255 -28.77436 1.000 17.62232 ? 128 TRP C C   1 
ATOM   3301 O O   . TRP C 1 128 ? 5.40738   46.79484 -28.11362 1.000 17.19180 ? 128 TRP C O   1 
ATOM   3302 C CB  . TRP C 1 128 ? 6.01416   44.03105 -29.92185 1.000 15.56182 ? 128 TRP C CB  1 
ATOM   3303 C CG  . TRP C 1 128 ? 5.20537   43.45958 -28.77078 1.000 13.52632 ? 128 TRP C CG  1 
ATOM   3304 C CD1 . TRP C 1 128 ? 3.87399   43.14050 -28.78898 1.000 15.37742 ? 128 TRP C CD1 1 
ATOM   3305 C CD2 . TRP C 1 128 ? 5.68847   43.07746 -27.47688 1.000 11.80275 ? 128 TRP C CD2 1 
ATOM   3306 N NE1 . TRP C 1 128 ? 3.49504   42.61482 -27.57531 1.000 13.26218 ? 128 TRP C NE1 1 
ATOM   3307 C CE2 . TRP C 1 128 ? 4.58812   42.56259 -26.75377 1.000 14.89987 ? 128 TRP C CE2 1 
ATOM   3308 C CE3 . TRP C 1 128 ? 6.93463   43.14213 -26.84864 1.000 14.91805 ? 128 TRP C CE3 1 
ATOM   3309 C CZ2 . TRP C 1 128 ? 4.70504   42.09251 -25.44483 1.000 12.26320 ? 128 TRP C CZ2 1 
ATOM   3310 C CZ3 . TRP C 1 128 ? 7.04604   42.68114 -25.53804 1.000 15.32127 ? 128 TRP C CZ3 1 
ATOM   3311 C CH2 . TRP C 1 128 ? 5.93397   42.17055 -24.85389 1.000 15.34069 ? 128 TRP C CH2 1 
ATOM   3312 N N   . PHE C 1 129 ? 7.55517   46.16667 -28.35722 1.000 16.41411 ? 129 PHE C N   1 
ATOM   3313 C CA  . PHE C 1 129 ? 7.96222   46.76246 -27.09177 1.000 15.09920 ? 129 PHE C CA  1 
ATOM   3314 C C   . PHE C 1 129 ? 7.80275   48.27664 -27.11271 1.000 18.71734 ? 129 PHE C C   1 
ATOM   3315 O O   . PHE C 1 129 ? 7.31919   48.86876 -26.14000 1.000 16.70249 ? 129 PHE C O   1 
ATOM   3316 C CB  . PHE C 1 129 ? 9.40938   46.37905 -26.78780 1.000 16.41583 ? 129 PHE C CB  1 
ATOM   3317 C CG  . PHE C 1 129 ? 9.96953   47.03459 -25.56612 1.000 18.44838 ? 129 PHE C CG  1 
ATOM   3318 C CD1 . PHE C 1 129 ? 9.64518   46.58514 -24.29193 1.000 17.73692 ? 129 PHE C CD1 1 
ATOM   3319 C CD2 . PHE C 1 129 ? 10.83261  48.11567 -25.69122 1.000 21.31217 ? 129 PHE C CD2 1 
ATOM   3320 C CE1 . PHE C 1 129 ? 10.17430  47.20571 -23.18041 1.000 19.95631 ? 129 PHE C CE1 1 
ATOM   3321 C CE2 . PHE C 1 129 ? 11.35785  48.73624 -24.58149 1.000 23.24803 ? 129 PHE C CE2 1 
ATOM   3322 C CZ  . PHE C 1 129 ? 11.03436  48.27843 -23.32172 1.000 23.16315 ? 129 PHE C CZ  1 
ATOM   3323 N N   . ASP C 1 130 ? 8.20947   48.92011 -28.21237 1.000 19.07706 ? 130 ASP C N   1 
ATOM   3324 C CA  . ASP C 1 130 ? 8.14210   50.37583 -28.28770 1.000 20.89635 ? 130 ASP C CA  1 
ATOM   3325 C C   . ASP C 1 130 ? 6.71230   50.88251 -28.20041 1.000 20.39486 ? 130 ASP C C   1 
ATOM   3326 O O   . ASP C 1 130 ? 6.48329   52.00721 -27.74597 1.000 24.26500 ? 130 ASP C O   1 
ATOM   3327 C CB  . ASP C 1 130 ? 8.80220   50.88153 -29.57610 1.000 22.08626 ? 130 ASP C CB  1 
ATOM   3328 C CG  . ASP C 1 130 ? 10.29074  50.60281 -29.61716 1.000 22.11637 ? 130 ASP C CG  1 
ATOM   3329 O OD1 . ASP C 1 130 ? 10.90012  50.39959 -28.54116 1.000 24.45066 ? 130 ASP C OD1 1 
ATOM   3330 O OD2 . ASP C 1 130 ? 10.85986  50.60674 -30.73139 1.000 32.10785 ? 130 ASP C OD2 1 
ATOM   3331 N N   . ASN C 1 131 ? 5.74247   50.07311 -28.61056 1.000 19.63221 ? 131 ASN C N   1 
ATOM   3332 C CA  . ASN C 1 131 ? 4.34424   50.46915 -28.55862 1.000 23.63587 ? 131 ASN C CA  1 
ATOM   3333 C C   . ASN C 1 131 ? 3.65889   50.11397 -27.24955 1.000 20.21420 ? 131 ASN C C   1 
ATOM   3334 O O   . ASN C 1 131 ? 2.47213   50.41662 -27.09235 1.000 21.30868 ? 131 ASN C O   1 
ATOM   3335 C CB  . ASN C 1 131 ? 3.58861   49.84531 -29.72618 1.000 20.15605 ? 131 ASN C CB  1 
ATOM   3336 C CG  . ASN C 1 131 ? 3.86516   50.56065 -31.02820 1.000 38.63254 ? 131 ASN C CG  1 
ATOM   3337 O OD1 . ASN C 1 131 ? 4.31506   51.71064 -31.02855 1.000 39.16080 ? 131 ASN C OD1 1 
ATOM   3338 N ND2 . ASN C 1 131 ? 3.64720   49.87243 -32.14631 1.000 40.92830 ? 131 ASN C ND2 1 
ATOM   3339 N N   . LEU C 1 132 ? 4.35436   49.47318 -26.31372 1.000 14.32867 ? 132 LEU C N   1 
ATOM   3340 C CA  . LEU C 1 132 ? 3.76569   49.27492 -25.00154 1.000 14.51769 ? 132 LEU C CA  1 
ATOM   3341 C C   . LEU C 1 132 ? 3.74064   50.59152 -24.23721 1.000 13.29739 ? 132 LEU C C   1 
ATOM   3342 O O   . LEU C 1 132 ? 4.47216   51.53671 -24.54481 1.000 16.71875 ? 132 LEU C O   1 
ATOM   3343 C CB  . LEU C 1 132 ? 4.54380   48.23356 -24.20095 1.000 15.32525 ? 132 LEU C CB  1 
ATOM   3344 C CG  . LEU C 1 132 ? 4.53144   46.82372 -24.79471 1.000 16.08706 ? 132 LEU C CG  1 
ATOM   3345 C CD1 . LEU C 1 132 ? 5.42777   45.95518 -23.96571 1.000 19.32968 ? 132 LEU C CD1 1 
ATOM   3346 C CD2 . LEU C 1 132 ? 3.13660   46.20919 -24.93388 1.000 16.07938 ? 132 LEU C CD2 1 
ATOM   3347 N N   . SER C 1 133 ? 2.88210   50.64631 -23.22756 1.000 14.92381 ? 133 SER C N   1 
ATOM   3348 C CA  . SER C 1 133 ? 2.78358   51.84323 -22.41285 1.000 15.59728 ? 133 SER C CA  1 
ATOM   3349 C C   . SER C 1 133 ? 4.09138   52.09185 -21.66771 1.000 16.49112 ? 133 SER C C   1 
ATOM   3350 O O   . SER C 1 133 ? 4.91317   51.19113 -21.45831 1.000 14.00908 ? 133 SER C O   1 
ATOM   3351 C CB  . SER C 1 133 ? 1.60909   51.73050 -21.43584 1.000 16.11124 ? 133 SER C CB  1 
ATOM   3352 O OG  . SER C 1 133 ? 1.94623   50.98738 -20.27686 1.000 14.72786 ? 133 SER C OG  1 
ATOM   3353 N N   . SER C 1 134 ? 4.28791   53.35301 -21.28024 1.000 14.09769 ? 134 SER C N   1 
ATOM   3354 C CA  . SER C 1 134 ? 5.53842   53.74214 -20.63729 1.000 15.37022 ? 134 SER C CA  1 
ATOM   3355 C C   . SER C 1 134 ? 5.80955   52.92360 -19.37627 1.000 15.05520 ? 134 SER C C   1 
ATOM   3356 O O   . SER C 1 134 ? 6.94360   52.47808 -19.14796 1.000 14.04730 ? 134 SER C O   1 
ATOM   3357 C CB  . SER C 1 134 ? 5.50367   55.23616 -20.30877 1.000 16.22598 ? 134 SER C CB  1 
ATOM   3358 O OG  . SER C 1 134 ? 4.45573   55.55912 -19.42238 1.000 21.92489 ? 134 SER C OG  1 
ATOM   3359 N N   . ASP C 1 135 ? 4.79293   52.74027 -18.52380 1.000 13.01610 ? 135 ASP C N   1 
ATOM   3360 C CA  . ASP C 1 135 ? 5.00239   51.99740 -17.28373 1.000 14.89776 ? 135 ASP C CA  1 
ATOM   3361 C C   . ASP C 1 135 ? 5.25473   50.52085 -17.54849 1.000 15.24243 ? 135 ASP C C   1 
ATOM   3362 O O   . ASP C 1 135 ? 5.99249   49.87775 -16.79578 1.000 15.32490 ? 135 ASP C O   1 
ATOM   3363 C CB  . ASP C 1 135 ? 3.81536   52.15779 -16.32104 1.000 15.61658 ? 135 ASP C CB  1 
ATOM   3364 C CG  . ASP C 1 135 ? 3.70560   53.56688 -15.75262 1.000 23.21589 ? 135 ASP C CG  1 
ATOM   3365 O OD1 . ASP C 1 135 ? 4.67646   54.32624 -15.91290 1.000 21.82245 ? 135 ASP C OD1 1 
ATOM   3366 O OD2 . ASP C 1 135 ? 2.69011   53.89583 -15.08554 1.000 22.12494 ? 135 ASP C OD2 1 
ATOM   3367 N N   . GLU C 1 136 ? 4.66658   49.97315 -18.61061 1.000 16.02353 ? 136 GLU C N   1 
ATOM   3368 C CA  . GLU C 1 136 ? 4.94119   48.58269 -18.95124 1.000 14.82147 ? 136 GLU C CA  1 
ATOM   3369 C C   . GLU C 1 136 ? 6.37809   48.41107 -19.40990 1.000 13.08831 ? 136 GLU C C   1 
ATOM   3370 O O   . GLU C 1 136 ? 7.05189   47.46053 -19.00225 1.000 14.26405 ? 136 GLU C O   1 
ATOM   3371 C CB  . GLU C 1 136 ? 3.98226   48.10373 -20.02645 1.000 15.00780 ? 136 GLU C CB  1 
ATOM   3372 C CG  . GLU C 1 136 ? 2.60789   47.81581 -19.48752 1.000 19.52712 ? 136 GLU C CG  1 
ATOM   3373 C CD  . GLU C 1 136 ? 1.62212   47.61772 -20.58969 1.000 21.45023 ? 136 GLU C CD  1 
ATOM   3374 O OE1 . GLU C 1 136 ? 1.28366   48.60498 -21.26947 1.000 19.27186 ? 136 GLU C OE1 1 
ATOM   3375 O OE2 . GLU C 1 136 ? 1.23880   46.45666 -20.82877 1.000 20.72175 ? 136 GLU C OE2 1 
ATOM   3376 N N   . ARG C 1 137 ? 6.85563   49.31825 -20.27375 1.000 13.00930 ? 137 ARG C N   1 
ATOM   3377 C CA  . ARG C 1 137 ? 8.24595   49.27317 -20.71812 1.000 15.12995 ? 137 ARG C CA  1 
ATOM   3378 C C   . ARG C 1 137 ? 9.19710   49.35940 -19.53124 1.000 16.12764 ? 137 ARG C C   1 
ATOM   3379 O O   . ARG C 1 137 ? 10.18261  48.61300 -19.45763 1.000 13.12285 ? 137 ARG C O   1 
ATOM   3380 C CB  . ARG C 1 137 ? 8.52145   50.42083 -21.69615 1.000 13.30027 ? 137 ARG C CB  1 
ATOM   3381 C CG  . ARG C 1 137 ? 7.76499   50.34267 -23.01960 1.000 13.76026 ? 137 ARG C CG  1 
ATOM   3382 C CD  . ARG C 1 137 ? 8.41458   51.20199 -24.10670 1.000 18.06809 ? 137 ARG C CD  1 
ATOM   3383 N NE  . ARG C 1 137 ? 8.57548   52.60697 -23.73205 1.000 19.18351 ? 137 ARG C NE  1 
ATOM   3384 C CZ  . ARG C 1 137 ? 7.63344   53.53436 -23.87016 1.000 22.42733 ? 137 ARG C CZ  1 
ATOM   3385 N NH1 . ARG C 1 137 ? 6.40785   53.22814 -24.26030 1.000 21.62154 ? 137 ARG C NH1 1 
ATOM   3386 N NH2 . ARG C 1 137 ? 7.93602   54.80693 -23.64305 1.000 27.50509 ? 137 ARG C NH2 1 
ATOM   3387 N N   . ALA C 1 138 ? 8.91152   50.26215 -18.58441 1.000 14.55261 ? 138 ALA C N   1 
ATOM   3388 C CA  . ALA C 1 138 ? 9.80099   50.45232 -17.43942 1.000 16.31407 ? 138 ALA C CA  1 
ATOM   3389 C C   . ALA C 1 138 ? 9.87070   49.19859 -16.57738 1.000 16.77779 ? 138 ALA C C   1 
ATOM   3390 O O   . ALA C 1 138 ? 10.95166  48.80994 -16.12201 1.000 16.47499 ? 138 ALA C O   1 
ATOM   3391 C CB  . ALA C 1 138 ? 9.33899   51.64601 -16.59719 1.000 16.62499 ? 138 ALA C CB  1 
ATOM   3392 N N   . PHE C 1 139 ? 8.72167   48.56458 -16.33025 1.000 15.06785 ? 139 PHE C N   1 
ATOM   3393 C CA  . PHE C 1 139 ? 8.69957   47.33162 -15.55349 1.000 17.42490 ? 139 PHE C CA  1 
ATOM   3394 C C   . PHE C 1 139 ? 9.52388   46.25692 -16.23519 1.000 14.25109 ? 139 PHE C C   1 
ATOM   3395 O O   . PHE C 1 139 ? 10.28296  45.52628 -15.59769 1.000 16.41069 ? 139 PHE C O   1 
ATOM   3396 C CB  . PHE C 1 139 ? 7.25942   46.85710 -15.39244 1.000 13.03368 ? 139 PHE C CB  1 
ATOM   3397 C CG  . PHE C 1 139 ? 7.12257   45.63187 -14.54341 1.000 17.64405 ? 139 PHE C CG  1 
ATOM   3398 C CD1 . PHE C 1 139 ? 7.35004   45.68898 -13.18445 1.000 22.49843 ? 139 PHE C CD1 1 
ATOM   3399 C CD2 . PHE C 1 139 ? 6.76233   44.41988 -15.10877 1.000 14.36975 ? 139 PHE C CD2 1 
ATOM   3400 C CE1 . PHE C 1 139 ? 7.22266   44.56343 -12.40506 1.000 25.64481 ? 139 PHE C CE1 1 
ATOM   3401 C CE2 . PHE C 1 139 ? 6.62893   43.29364 -14.33323 1.000 19.26736 ? 139 PHE C CE2 1 
ATOM   3402 C CZ  . PHE C 1 139 ? 6.85820   43.35976 -12.98628 1.000 24.18809 ? 139 PHE C CZ  1 
ATOM   3403 N N   . MET C 1 140 ? 9.40730   46.18201 -17.54628 1.000 14.91520 ? 140 MET C N   1 
ATOM   3404 C CA  . MET C 1 140 ? 10.05312  45.14233 -18.31411 1.000 18.13019 ? 140 MET C CA  1 
ATOM   3405 C C   . MET C 1 140 ? 11.56465  45.35374 -18.27993 1.000 17.79991 ? 140 MET C C   1 
ATOM   3406 O O   . MET C 1 140 ? 12.33558  44.41183 -18.04818 1.000 18.38081 ? 140 MET C O   1 
ATOM   3407 C CB  . MET C 1 140 ? 9.45144   45.27743 -19.69981 1.000 19.24670 ? 140 MET C CB  1 
ATOM   3408 C CG  . MET C 1 140 ? 8.34547   44.30627 -19.94921 1.000 16.69634 ? 140 MET C CG  1 
ATOM   3409 S SD  . MET C 1 140 ? 7.91977   44.39030 -21.66933 1.000 18.33702 ? 140 MET C SD  1 
ATOM   3410 C CE  . MET C 1 140 ? 6.28661   43.63846 -21.57160 1.000 22.22740 ? 140 MET C CE  1 
ATOM   3411 N N   . GLU C 1 141 ? 11.98860  46.61855 -18.40052 1.000 19.39664 ? 141 GLU C N   1 
ATOM   3412 C CA  . GLU C 1 141 ? 13.39888  46.99951 -18.36839 1.000 20.96818 ? 141 GLU C CA  1 
ATOM   3413 C C   . GLU C 1 141 ? 14.08537  46.68102 -17.04617 1.000 20.10417 ? 141 GLU C C   1 
ATOM   3414 O O   . GLU C 1 141 ? 15.31324  46.55504 -17.02510 1.000 24.56230 ? 141 GLU C O   1 
ATOM   3415 C CB  . GLU C 1 141 ? 13.55138  48.49902 -18.63588 1.000 24.58673 ? 141 GLU C CB  1 
ATOM   3416 C CG  . GLU C 1 141 ? 13.62805  48.92439 -20.08910 1.000 29.25818 ? 141 GLU C CG  1 
ATOM   3417 C CD  . GLU C 1 141 ? 13.37932  50.42188 -20.24514 1.000 27.72056 ? 141 GLU C CD  1 
ATOM   3418 O OE1 . GLU C 1 141 ? 13.60525  51.16683 -19.26278 1.000 33.26845 ? 141 GLU C OE1 1 
ATOM   3419 O OE2 . GLU C 1 141 ? 12.98176  50.85026 -21.34406 1.000 38.70268 ? 141 GLU C OE2 1 
ATOM   3420 N N   . THR C 1 142 ? 13.34624  46.57325 -15.93732 1.000 19.31884 ? 142 THR C N   1 
ATOM   3421 C CA  . THR C 1 142 ? 14.00493  46.21395 -14.68473 1.000 18.86705 ? 142 THR C CA  1 
ATOM   3422 C C   . THR C 1 142 ? 14.50064  44.77062 -14.69803 1.000 20.94252 ? 142 THR C C   1 
ATOM   3423 O O   . THR C 1 142 ? 15.38835  44.42022 -13.90968 1.000 24.73875 ? 142 THR C O   1 
ATOM   3424 C CB  . THR C 1 142 ? 13.07998  46.43243 -13.48461 1.000 23.27289 ? 142 THR C CB  1 
ATOM   3425 O OG1 . THR C 1 142 ? 13.85794  46.43175 -12.28385 1.000 30.59180 ? 142 THR C OG1 1 
ATOM   3426 C CG2 . THR C 1 142 ? 12.06578  45.30938 -13.35409 1.000 23.32854 ? 142 THR C CG2 1 
ATOM   3427 N N   . ASN C 1 143 ? 13.96040  43.93578 -15.58073 1.000 16.65364 ? 143 ASN C N   1 
ATOM   3428 C CA  . ASN C 1 143 ? 14.27518  42.50585 -15.60476 1.000 15.57811 ? 143 ASN C CA  1 
ATOM   3429 C C   . ASN C 1 143 ? 15.32527  42.20872 -16.67221 1.000 20.81895 ? 143 ASN C C   1 
ATOM   3430 O O   . ASN C 1 143 ? 15.10537  41.45641 -17.62393 1.000 18.61941 ? 143 ASN C O   1 
ATOM   3431 C CB  . ASN C 1 143 ? 13.00193  41.70295 -15.84028 1.000 18.88467 ? 143 ASN C CB  1 
ATOM   3432 C CG  . ASN C 1 143 ? 12.05206  41.78287 -14.66650 1.000 18.08109 ? 143 ASN C CG  1 
ATOM   3433 O OD1 . ASN C 1 143 ? 12.48209  41.81664 -13.50872 1.000 20.65575 ? 143 ASN C OD1 1 
ATOM   3434 N ND2 . ASN C 1 143 ? 10.75543  41.84431 -14.95441 1.000 20.50978 ? 143 ASN C ND2 1 
ATOM   3435 N N   . VAL C 1 144 ? 16.49423  42.82028 -16.50829 1.000 17.32605 ? 144 VAL C N   1 
ATOM   3436 C CA  . VAL C 1 144 ? 17.63032  42.58620 -17.38981 1.000 18.87740 ? 144 VAL C CA  1 
ATOM   3437 C C   . VAL C 1 144 ? 18.86425  42.43128 -16.51652 1.000 26.01251 ? 144 VAL C C   1 
ATOM   3438 O O   . VAL C 1 144 ? 19.25700  43.37354 -15.81925 1.000 25.92533 ? 144 VAL C O   1 
ATOM   3439 C CB  . VAL C 1 144 ? 17.82891  43.71650 -18.41753 1.000 25.85567 ? 144 VAL C CB  1 
ATOM   3440 C CG1 . VAL C 1 144 ? 18.96429  43.36435 -19.37332 1.000 31.07381 ? 144 VAL C CG1 1 
ATOM   3441 C CG2 . VAL C 1 144 ? 16.55357  43.94268 -19.22290 1.000 22.91917 ? 144 VAL C CG2 1 
ATOM   3442 N N   . ASP C 1 145 ? 19.45029  41.23510 -16.52462 1.000 26.64885 ? 145 ASP C N   1 
ATOM   3443 C CA  . ASP C 1 145 ? 20.72859  40.99683 -15.85904 1.000 34.23160 ? 145 ASP C CA  1 
ATOM   3444 C C   . ASP C 1 145 ? 21.82859  41.30542 -16.87268 1.000 38.28371 ? 145 ASP C C   1 
ATOM   3445 O O   . ASP C 1 145 ? 22.42229  40.41687 -17.48959 1.000 44.00408 ? 145 ASP C O   1 
ATOM   3446 C CB  . ASP C 1 145 ? 20.80174  39.57025 -15.32982 1.000 24.27050 ? 145 ASP C CB  1 
ATOM   3447 C CG  . ASP C 1 145 ? 21.95558  39.36345 -14.37022 1.000 34.84765 ? 145 ASP C CG  1 
ATOM   3448 O OD1 . ASP C 1 145 ? 23.10789  39.66925 -14.74894 1.000 38.18315 ? 145 ASP C OD1 1 
ATOM   3449 O OD2 . ASP C 1 145 ? 21.70552  38.91426 -13.23236 1.000 30.43811 ? 145 ASP C OD2 1 
ATOM   3450 N N   . VAL C 1 146 ? 22.09357  42.60566 -17.02761 1.000 44.42938 ? 146 VAL C N   1 
ATOM   3451 C CA  . VAL C 1 146 ? 22.96839  43.19299 -18.05941 1.000 47.28248 ? 146 VAL C CA  1 
ATOM   3452 C C   . VAL C 1 146 ? 23.00551  42.38427 -19.35486 1.000 50.35801 ? 146 VAL C C   1 
ATOM   3453 O O   . VAL C 1 146 ? 22.01633  42.32516 -20.08791 1.000 49.32176 ? 146 VAL C O   1 
ATOM   3454 C CB  . VAL C 1 146 ? 24.40828  43.41131 -17.52318 1.000 49.22926 ? 146 VAL C CB  1 
ATOM   3455 C CG1 . VAL C 1 146 ? 24.39174  44.37698 -16.34358 1.000 48.37675 ? 146 VAL C CG1 1 
ATOM   3456 C CG2 . VAL C 1 146 ? 25.08121  42.09005 -17.15637 1.000 44.46149 ? 146 VAL C CG2 1 
HETATM 3457 S S   . SO4 D 2 .   ? 8.11058   9.15180  -27.96366 1.000 36.11737 ? 201 SO4 A S   1 
HETATM 3458 O O1  . SO4 D 2 .   ? 9.00119   10.14721 -27.37361 1.000 28.80352 ? 201 SO4 A O1  1 
HETATM 3459 O O2  . SO4 D 2 .   ? 6.72401   9.27793  -27.53358 1.000 30.63433 ? 201 SO4 A O2  1 
HETATM 3460 O O3  . SO4 D 2 .   ? 8.61622   7.83079  -27.57369 1.000 22.00475 ? 201 SO4 A O3  1 
HETATM 3461 O O4  . SO4 D 2 .   ? 8.12778   9.27575  -29.41415 1.000 36.48124 ? 201 SO4 A O4  1 
HETATM 3462 S S   . SO4 E 2 .   ? -11.15558 22.23913 -23.33939 1.000 27.41680 ? 201 SO4 B S   1 
HETATM 3463 O O1  . SO4 E 2 .   ? -10.83452 22.72863 -24.67620 1.000 17.57175 ? 201 SO4 B O1  1 
HETATM 3464 O O2  . SO4 E 2 .   ? -12.47674 22.78600 -23.02120 1.000 18.86041 ? 201 SO4 B O2  1 
HETATM 3465 O O3  . SO4 E 2 .   ? -11.16615 20.76914 -23.26838 1.000 27.57882 ? 201 SO4 B O3  1 
HETATM 3466 O O4  . SO4 E 2 .   ? -10.11561 22.74620 -22.47026 1.000 22.19771 ? 201 SO4 B O4  1 
HETATM 3467 S S   . SO4 F 2 .   ? 9.50765   32.93347 -27.61203 1.000 17.08562 ? 201 SO4 C S   1 
HETATM 3468 O O1  . SO4 F 2 .   ? 9.25306   32.21988 -28.85648 1.000 13.86808 ? 201 SO4 C O1  1 
HETATM 3469 O O2  . SO4 F 2 .   ? 9.87911   31.94509 -26.63070 1.000 17.04885 ? 201 SO4 C O2  1 
HETATM 3470 O O3  . SO4 F 2 .   ? 8.29796   33.65662 -27.20273 1.000 18.97762 ? 201 SO4 C O3  1 
HETATM 3471 O O4  . SO4 F 2 .   ? 10.60967  33.89174 -27.83052 1.000 15.77645 ? 201 SO4 C O4  1 
HETATM 3472 O O   . HOH G 3 .   ? 22.55127  -1.31604 -24.57199 1.000 33.39789 ? 301 HOH A O   1 
HETATM 3473 O O   . HOH G 3 .   ? 9.47222   11.94991 -26.13198 1.000 29.97880 ? 302 HOH A O   1 
HETATM 3474 O O   . HOH G 3 .   ? 10.30574  14.99676 -10.32347 1.000 21.60644 ? 303 HOH A O   1 
HETATM 3475 O O   . HOH G 3 .   ? 8.75203   10.17674 -40.02711 1.000 31.12715 ? 304 HOH A O   1 
HETATM 3476 O O   . HOH G 3 .   ? 7.61677   20.90190 -9.12587  1.000 23.36126 ? 305 HOH A O   1 
HETATM 3477 O O   . HOH G 3 .   ? -10.99514 14.39373 -6.58534  1.000 28.47454 ? 306 HOH A O   1 
HETATM 3478 O O   . HOH G 3 .   ? 7.041     12.891   -37.812   1.000 28.15389 ? 307 HOH A O   1 
HETATM 3479 O O   . HOH G 3 .   ? 7.19846   16.19960 -2.29276  1.000 30.73888 ? 308 HOH A O   1 
HETATM 3480 O O   . HOH G 3 .   ? 12.99392  19.73634 -40.00252 1.000 31.74666 ? 309 HOH A O   1 
HETATM 3481 O O   . HOH G 3 .   ? -11.98276 2.23775  -11.71357 1.000 19.72757 ? 310 HOH A O   1 
HETATM 3482 O O   . HOH G 3 .   ? 30.49092  9.53423  -25.21713 1.000 35.79910 ? 311 HOH A O   1 
HETATM 3483 O O   . HOH G 3 .   ? -4.22535  -2.93279 -15.84310 1.000 28.13964 ? 312 HOH A O   1 
HETATM 3484 O O   . HOH G 3 .   ? -9.84919  -0.53510 -20.81611 1.000 27.16610 ? 313 HOH A O   1 
HETATM 3485 O O   . HOH G 3 .   ? -3.69311  -1.90807 -27.55524 1.000 32.96332 ? 314 HOH A O   1 
HETATM 3486 O O   . HOH G 3 .   ? -10.71940 3.34465  -24.58013 1.000 27.09037 ? 315 HOH A O   1 
HETATM 3487 O O   . HOH G 3 .   ? -6.83805  16.04759 -6.07275  1.000 19.84167 ? 316 HOH A O   1 
HETATM 3488 O O   . HOH G 3 .   ? 4.72299   17.17052 -38.12652 1.000 32.73469 ? 317 HOH A O   1 
HETATM 3489 O O   . HOH G 3 .   ? 6.43369   -0.85262 -6.45914  1.000 27.80105 ? 318 HOH A O   1 
HETATM 3490 O O   . HOH G 3 .   ? 18.03155  0.04266  -37.58117 1.000 49.11223 ? 319 HOH A O   1 
HETATM 3491 O O   . HOH G 3 .   ? 1.69318   -1.19234 -17.97211 1.000 21.90459 ? 320 HOH A O   1 
HETATM 3492 O O   . HOH G 3 .   ? 24.88834  17.12641 -25.98994 1.000 22.11197 ? 321 HOH A O   1 
HETATM 3493 O O   . HOH G 3 .   ? -1.77505  0.62535  -1.10274  1.000 37.99801 ? 322 HOH A O   1 
HETATM 3494 O O   . HOH G 3 .   ? -6.01956  3.84294  -2.76038  1.000 34.44599 ? 323 HOH A O   1 
HETATM 3495 O O   . HOH G 3 .   ? 7.65467   15.71425 -37.10292 1.000 29.20294 ? 324 HOH A O   1 
HETATM 3496 O O   . HOH G 3 .   ? -1.14839  15.74731 -33.47450 1.000 27.40601 ? 325 HOH A O   1 
HETATM 3497 O O   . HOH G 3 .   ? 28.76170  5.51361  -19.21064 1.000 26.76420 ? 326 HOH A O   1 
HETATM 3498 O O   . HOH G 3 .   ? 11.88690  9.67879  -25.89533 1.000 27.45402 ? 327 HOH A O   1 
HETATM 3499 O O   . HOH G 3 .   ? 6.71756   2.24166  0.04739   1.000 25.76200 ? 328 HOH A O   1 
HETATM 3500 O O   . HOH G 3 .   ? -2.87423  12.41858 -6.13178  1.000 15.70675 ? 329 HOH A O   1 
HETATM 3501 O O   . HOH G 3 .   ? 2.69600   18.92299 -32.76874 1.000 26.83562 ? 330 HOH A O   1 
HETATM 3502 O O   . HOH G 3 .   ? 1.26484   11.41826 -36.23374 1.000 24.71437 ? 331 HOH A O   1 
HETATM 3503 O O   . HOH G 3 .   ? 23.94988  4.86542  -13.90669 1.000 34.85722 ? 332 HOH A O   1 
HETATM 3504 O O   . HOH G 3 .   ? 3.02646   10.89651 -31.91326 1.000 13.19299 ? 333 HOH A O   1 
HETATM 3505 O O   . HOH G 3 .   ? -0.93800  16.13431 0.65682   1.000 23.96876 ? 334 HOH A O   1 
HETATM 3506 O O   . HOH G 3 .   ? 9.37557   -0.09654 -16.31660 1.000 31.31528 ? 335 HOH A O   1 
HETATM 3507 O O   . HOH G 3 .   ? -11.87235 5.65451  -21.35954 1.000 16.88110 ? 336 HOH A O   1 
HETATM 3508 O O   . HOH G 3 .   ? 5.82265   4.25766  -32.56426 1.000 30.44257 ? 337 HOH A O   1 
HETATM 3509 O O   . HOH G 3 .   ? 4.90331   20.69440 -35.65958 1.000 28.90667 ? 338 HOH A O   1 
HETATM 3510 O O   . HOH G 3 .   ? 2.96728   20.12308 -17.92662 1.000 24.74056 ? 339 HOH A O   1 
HETATM 3511 O O   . HOH G 3 .   ? -5.90297  -0.92583 -21.53833 1.000 27.06765 ? 340 HOH A O   1 
HETATM 3512 O O   . HOH G 3 .   ? -8.36441  19.17149 0.05494   1.000 21.49034 ? 341 HOH A O   1 
HETATM 3513 O O   . HOH G 3 .   ? -2.79087  18.30622 -4.90105  1.000 14.31256 ? 342 HOH A O   1 
HETATM 3514 O O   . HOH G 3 .   ? 7.90393   13.15350 -1.52908  1.000 29.25130 ? 343 HOH A O   1 
HETATM 3515 O O   . HOH G 3 .   ? -10.37446 13.86111 -8.93385  1.000 22.37991 ? 344 HOH A O   1 
HETATM 3516 O O   . HOH G 3 .   ? -5.22769  0.21638  -24.26728 1.000 22.90478 ? 345 HOH A O   1 
HETATM 3517 O O   . HOH G 3 .   ? 19.61812  12.54208 -33.42439 1.000 32.20014 ? 346 HOH A O   1 
HETATM 3518 O O   . HOH G 3 .   ? 25.30103  -0.26903 -18.57548 1.000 25.80766 ? 347 HOH A O   1 
HETATM 3519 O O   . HOH G 3 .   ? 2.03145   13.27090 -34.78904 1.000 21.83308 ? 348 HOH A O   1 
HETATM 3520 O O   . HOH G 3 .   ? -11.29290 13.59125 -11.74559 1.000 15.86751 ? 349 HOH A O   1 
HETATM 3521 O O   . HOH G 3 .   ? -4.19113  15.46578 -6.79660  1.000 16.90925 ? 350 HOH A O   1 
HETATM 3522 O O   . HOH G 3 .   ? 11.89969  21.09431 -35.29061 1.000 13.76200 ? 351 HOH A O   1 
HETATM 3523 O O   . HOH G 3 .   ? -6.36969  8.43793  -1.15438  1.000 42.92632 ? 352 HOH A O   1 
HETATM 3524 O O   . HOH G 3 .   ? -3.94889  -2.63120 -19.53949 1.000 29.99584 ? 353 HOH A O   1 
HETATM 3525 O O   . HOH G 3 .   ? 26.60743  -1.09774 -23.80253 1.000 31.87229 ? 354 HOH A O   1 
HETATM 3526 O O   . HOH G 3 .   ? -1.30592  -2.00238 -4.84298  1.000 34.56088 ? 355 HOH A O   1 
HETATM 3527 O O   . HOH G 3 .   ? -5.40176  9.61600  -30.29250 1.000 13.08455 ? 356 HOH A O   1 
HETATM 3528 O O   . HOH G 3 .   ? 2.29253   11.29060 -3.90245  1.000 17.83413 ? 357 HOH A O   1 
HETATM 3529 O O   . HOH G 3 .   ? 0.72004   -1.08730 -6.72702  1.000 27.77407 ? 358 HOH A O   1 
HETATM 3530 O O   . HOH G 3 .   ? 24.09057  -1.40063 -29.54851 1.000 42.22929 ? 359 HOH A O   1 
HETATM 3531 O O   . HOH G 3 .   ? -3.18039  19.70422 2.41476   1.000 33.09962 ? 360 HOH A O   1 
HETATM 3532 O O   . HOH G 3 .   ? -5.66794  18.52987 -4.42179  1.000 14.88852 ? 361 HOH A O   1 
HETATM 3533 O O   . HOH G 3 .   ? 24.02965  8.39150  -21.96733 1.000 25.37031 ? 362 HOH A O   1 
HETATM 3534 O O   . HOH G 3 .   ? 28.43193  0.46937  -23.94294 1.000 27.88329 ? 363 HOH A O   1 
HETATM 3535 O O   . HOH G 3 .   ? 7.97191   8.85562  -2.13493  1.000 29.92662 ? 364 HOH A O   1 
HETATM 3536 O O   . HOH G 3 .   ? 10.40215  5.53825  -16.03433 1.000 17.18695 ? 365 HOH A O   1 
HETATM 3537 O O   . HOH G 3 .   ? 3.35983   -1.51988 -11.80089 1.000 26.39358 ? 366 HOH A O   1 
HETATM 3538 O O   . HOH G 3 .   ? 2.88270   20.28389 -28.68240 1.000 20.68651 ? 367 HOH A O   1 
HETATM 3539 O O   . HOH G 3 .   ? 8.40779   4.69985  -31.26145 1.000 31.72565 ? 368 HOH A O   1 
HETATM 3540 O O   . HOH G 3 .   ? -2.69188  16.42683 -9.17237  1.000 14.70641 ? 369 HOH A O   1 
HETATM 3541 O O   . HOH G 3 .   ? 5.54977   20.31457 -3.33468  1.000 24.34287 ? 370 HOH A O   1 
HETATM 3542 O O   . HOH G 3 .   ? 3.59973   0.00000  0.00000   0.50  35.27891 ? 371 HOH A O   1 
HETATM 3543 O O   . HOH G 3 .   ? -3.46635  22.94383 -0.59288  1.000 22.90014 ? 372 HOH A O   1 
HETATM 3544 O O   . HOH G 3 .   ? -8.87798  -0.24174 -10.87647 1.000 38.30579 ? 373 HOH A O   1 
HETATM 3545 O O   . HOH G 3 .   ? -7.53696  3.81925  -30.34691 1.000 23.45944 ? 374 HOH A O   1 
HETATM 3546 O O   . HOH G 3 .   ? 1.51374   -1.42583 -30.60516 1.000 29.15149 ? 375 HOH A O   1 
HETATM 3547 O O   . HOH G 3 .   ? 9.44524   -4.85892 -25.89336 1.000 43.89130 ? 376 HOH A O   1 
HETATM 3548 O O   . HOH G 3 .   ? 2.17229   8.16082  2.27137   1.000 35.82798 ? 377 HOH A O   1 
HETATM 3549 O O   . HOH G 3 .   ? 9.74253   -1.04897 -14.23725 1.000 34.09321 ? 378 HOH A O   1 
HETATM 3550 O O   . HOH G 3 .   ? -2.71592  11.79336 -34.83946 1.000 18.29999 ? 379 HOH A O   1 
HETATM 3551 O O   . HOH G 3 .   ? 0.97009   18.22759 -8.56206  1.000 11.19389 ? 380 HOH A O   1 
HETATM 3552 O O   . HOH G 3 .   ? 0.72519   19.32420 -24.54725 1.000 11.39547 ? 381 HOH A O   1 
HETATM 3553 O O   . HOH G 3 .   ? 9.71046   14.99809 -36.93469 1.000 29.32490 ? 382 HOH A O   1 
HETATM 3554 O O   . HOH G 3 .   ? -8.61438  20.15035 -22.03968 1.000 23.28043 ? 383 HOH A O   1 
HETATM 3555 O O   . HOH G 3 .   ? 17.83425  19.02848 -34.47850 1.000 21.02292 ? 384 HOH A O   1 
HETATM 3556 O O   . HOH G 3 .   ? -13.89184 17.58996 -3.09871  1.000 27.46114 ? 385 HOH A O   1 
HETATM 3557 O O   . HOH G 3 .   ? -10.10443 6.02257  -5.85517  1.000 26.48808 ? 386 HOH A O   1 
HETATM 3558 O O   . HOH G 3 .   ? 8.90539   13.48483 -34.84274 1.000 17.10528 ? 387 HOH A O   1 
HETATM 3559 O O   . HOH G 3 .   ? -7.93115  0.64649  -8.69622  1.000 29.06678 ? 388 HOH A O   1 
HETATM 3560 O O   . HOH G 3 .   ? 21.06848  5.55475  -13.11421 1.000 37.37201 ? 389 HOH A O   1 
HETATM 3561 O O   . HOH G 3 .   ? -14.01212 24.18005 -2.55993  1.000 21.24413 ? 390 HOH A O   1 
HETATM 3562 O O   . HOH G 3 .   ? 3.16863   -4.80252 -23.02259 1.000 38.23353 ? 391 HOH A O   1 
HETATM 3563 O O   . HOH G 3 .   ? 5.28557   6.33958  -37.18990 1.000 15.44827 ? 392 HOH A O   1 
HETATM 3564 O O   . HOH G 3 .   ? -0.88574  2.36239  -35.57312 1.000 32.24928 ? 393 HOH A O   1 
HETATM 3565 O O   . HOH G 3 .   ? 1.57439   4.73713  -34.58655 1.000 15.61440 ? 394 HOH A O   1 
HETATM 3566 O O   . HOH G 3 .   ? -11.45056 1.07401  -17.96427 1.000 39.99117 ? 395 HOH A O   1 
HETATM 3567 O O   . HOH G 3 .   ? 22.42298  14.80013 -30.64578 1.000 20.43764 ? 396 HOH A O   1 
HETATM 3568 O O   . HOH G 3 .   ? -0.42507  -1.75007 -13.21899 1.000 23.04946 ? 397 HOH A O   1 
HETATM 3569 O O   . HOH G 3 .   ? 24.09056  2.90501  -35.75585 1.000 42.91860 ? 398 HOH A O   1 
HETATM 3570 O O   . HOH G 3 .   ? 34.424    3.798    -26.713   1.000 27.77362 ? 399 HOH A O   1 
HETATM 3571 O O   . HOH G 3 .   ? -1.22531  -3.06088 -24.19141 1.000 31.60939 ? 400 HOH A O   1 
HETATM 3572 O O   . HOH G 3 .   ? -9.55459  13.72206 -4.28542  1.000 24.32539 ? 401 HOH A O   1 
HETATM 3573 O O   . HOH G 3 .   ? 0.10358   17.69808 -29.55020 1.000 25.94475 ? 402 HOH A O   1 
HETATM 3574 O O   . HOH G 3 .   ? -1.36925  3.78508  -3.70259  1.000 27.04202 ? 403 HOH A O   1 
HETATM 3575 O O   . HOH G 3 .   ? 32.66873  9.29685  -24.32375 1.000 32.73067 ? 404 HOH A O   1 
HETATM 3576 O O   . HOH G 3 .   ? 32.232    5.157    -28.458   1.000 32.18994 ? 405 HOH A O   1 
HETATM 3577 O O   . HOH G 3 .   ? 11.67921  19.62688 -37.48611 1.000 24.93819 ? 406 HOH A O   1 
HETATM 3578 O O   . HOH G 3 .   ? 15.27853  -0.09384 -9.96571  1.000 32.86338 ? 407 HOH A O   1 
HETATM 3579 O O   . HOH G 3 .   ? -0.98983  -1.97527 -30.78818 1.000 38.29443 ? 408 HOH A O   1 
HETATM 3580 O O   . HOH G 3 .   ? 31.348    2.875    -28.888   1.000 38.03446 ? 409 HOH A O   1 
HETATM 3581 O O   . HOH G 3 .   ? 2.73868   9.38191  -29.63636 1.000 17.84610 ? 410 HOH A O   1 
HETATM 3582 O O   . HOH G 3 .   ? 9.74678   3.57200  -23.62806 1.000 28.77648 ? 411 HOH A O   1 
HETATM 3583 O O   . HOH G 3 .   ? 0.47405   4.80346  -1.78211  1.000 24.40960 ? 412 HOH A O   1 
HETATM 3584 O O   . HOH G 3 .   ? 4.22095   -4.81818 -20.67673 1.000 40.34211 ? 413 HOH A O   1 
HETATM 3585 O O   . HOH G 3 .   ? -12.56710 15.75512 -3.25270  1.000 30.78045 ? 414 HOH A O   1 
HETATM 3586 O O   . HOH G 3 .   ? -8.28444  -3.31221 -13.25739 1.000 39.22764 ? 415 HOH A O   1 
HETATM 3587 O O   . HOH G 3 .   ? -18.12779 7.54472  -9.23257  1.000 28.98741 ? 416 HOH A O   1 
HETATM 3588 O O   . HOH G 3 .   ? 20.19099  -2.81253 -19.80956 1.000 36.01804 ? 417 HOH A O   1 
HETATM 3589 O O   . HOH G 3 .   ? -12.80555 7.24111  -5.08092  1.000 29.18202 ? 418 HOH A O   1 
HETATM 3590 O O   . HOH G 3 .   ? -4.673    2.131    -37.267   1.000 30.14335 ? 419 HOH A O   1 
HETATM 3591 O O   . HOH G 3 .   ? -9.72536  3.62233  -4.64294  1.000 35.95281 ? 420 HOH A O   1 
HETATM 3592 O O   . HOH G 3 .   ? 17.11300  20.51272 -37.01136 1.000 29.30249 ? 421 HOH A O   1 
HETATM 3593 O O   . HOH G 3 .   ? 24.270    -3.661   -18.619   1.000 38.39606 ? 422 HOH A O   1 
HETATM 3594 O O   . HOH G 3 .   ? 4.08948   18.80593 -1.73965  1.000 27.80543 ? 423 HOH A O   1 
HETATM 3595 O O   . HOH G 3 .   ? 26.57808  -0.38528 -31.14006 1.000 42.35276 ? 424 HOH A O   1 
HETATM 3596 O O   . HOH G 3 .   ? 2.80058   -2.84056 -16.10586 1.000 32.93826 ? 425 HOH A O   1 
HETATM 3597 O O   . HOH G 3 .   ? -1.87598  -4.06927 -22.10211 1.000 42.23873 ? 426 HOH A O   1 
HETATM 3598 O O   . HOH G 3 .   ? -12.61500 21.22145 0.72074   1.000 29.86562 ? 427 HOH A O   1 
HETATM 3599 O O   . HOH G 3 .   ? -9.05546  25.76966 2.20895   1.000 30.79760 ? 428 HOH A O   1 
HETATM 3600 O O   . HOH G 3 .   ? 11.512    5.313    -42.911   1.000 37.36596 ? 429 HOH A O   1 
HETATM 3601 O O   . HOH G 3 .   ? -3.19494  3.67268  -1.86086  1.000 35.10451 ? 430 HOH A O   1 
HETATM 3602 O O   . HOH G 3 .   ? -8.43610  4.01548  -28.23578 1.000 33.01309 ? 431 HOH A O   1 
HETATM 3603 O O   . HOH G 3 .   ? 2.88039   19.00045 0.50849   1.000 36.40862 ? 432 HOH A O   1 
HETATM 3604 O O   . HOH G 3 .   ? 1.19525   0.59511  -2.93096  1.000 30.10747 ? 433 HOH A O   1 
HETATM 3605 O O   . HOH G 3 .   ? 0.64312   -6.37273 -22.37906 1.000 40.11432 ? 434 HOH A O   1 
HETATM 3606 O O   . HOH G 3 .   ? 18.19034  16.43408 -35.15550 1.000 25.25199 ? 435 HOH A O   1 
HETATM 3607 O O   . HOH G 3 .   ? -14.27541 22.05781 -0.75361  1.000 27.89465 ? 436 HOH A O   1 
HETATM 3608 O O   . HOH G 3 .   ? 16.27814  10.41117 -37.80640 1.000 37.30653 ? 437 HOH A O   1 
HETATM 3609 O O   . HOH G 3 .   ? 3.12607   19.43048 -26.07364 1.000 18.63218 ? 438 HOH A O   1 
HETATM 3610 O O   . HOH G 3 .   ? -2.22522  -3.85533 -14.20504 1.000 33.27262 ? 439 HOH A O   1 
HETATM 3611 O O   . HOH G 3 .   ? 9.64585   1.46167  -0.55438  1.000 37.59668 ? 440 HOH A O   1 
HETATM 3612 O O   . HOH G 3 .   ? 0.78989   -2.24798 -11.06374 1.000 33.88234 ? 441 HOH A O   1 
HETATM 3613 O O   . HOH G 3 .   ? 0.26882   1.91029  -0.70740  1.000 42.29214 ? 442 HOH A O   1 
HETATM 3614 O O   . HOH G 3 .   ? 26.19910  16.15546 -28.70602 1.000 36.93298 ? 443 HOH A O   1 
HETATM 3615 O O   . HOH G 3 .   ? 3.115     15.328   -38.359   1.000 28.89473 ? 444 HOH A O   1 
HETATM 3616 O O   . HOH G 3 .   ? 4.32122   8.22836  1.61185   1.000 35.00304 ? 445 HOH A O   1 
HETATM 3617 O O   . HOH G 3 .   ? 10.01092  11.88063 -1.32497  1.000 32.36838 ? 446 HOH A O   1 
HETATM 3618 O O   . HOH G 3 .   ? 2.12690   -2.30606 -13.96977 1.000 37.01494 ? 447 HOH A O   1 
HETATM 3619 O O   . HOH G 3 .   ? 6.103     -3.042   -2.440    1.000 37.86069 ? 448 HOH A O   1 
HETATM 3620 O O   . HOH G 3 .   ? -8.72374  2.09458  -26.21548 1.000 28.88414 ? 449 HOH A O   1 
HETATM 3621 O O   . HOH G 3 .   ? 14.212    5.163    -43.392   1.000 37.99005 ? 450 HOH A O   1 
HETATM 3622 O O   . HOH G 3 .   ? 3.71092   21.80196 -32.49471 1.000 32.62970 ? 451 HOH A O   1 
HETATM 3623 O O   . HOH G 3 .   ? 4.31250   4.58134  -35.20400 1.000 23.82395 ? 452 HOH A O   1 
HETATM 3624 O O   . HOH G 3 .   ? -17.34289 5.12338  -12.21825 1.000 37.16996 ? 453 HOH A O   1 
HETATM 3625 O O   . HOH G 3 .   ? 4.14218   -2.90837 -9.67767  1.000 36.50325 ? 454 HOH A O   1 
HETATM 3626 O O   . HOH G 3 .   ? -4.90007  12.94765 -34.60771 1.000 28.56980 ? 455 HOH A O   1 
HETATM 3627 O O   . HOH G 3 .   ? -14.336   2.494    -14.716   1.000 42.06460 ? 456 HOH A O   1 
HETATM 3628 O O   . HOH G 3 .   ? 1.54904   15.39156 -36.16108 1.000 27.22609 ? 457 HOH A O   1 
HETATM 3629 O O   . HOH G 3 .   ? -7.53346  17.32240 1.63268   1.000 29.54344 ? 458 HOH A O   1 
HETATM 3630 O O   . HOH G 3 .   ? 20.29464  14.68328 -34.60570 1.000 33.63842 ? 459 HOH A O   1 
HETATM 3631 O O   . HOH G 3 .   ? 1.31340   17.93090 2.02483   1.000 34.27647 ? 460 HOH A O   1 
HETATM 3632 O O   . HOH G 3 .   ? -7.78657  0.04584  -25.47734 1.000 33.32483 ? 461 HOH A O   1 
HETATM 3633 O O   . HOH G 3 .   ? 19.77726  -1.42984 -25.28066 1.000 37.19033 ? 462 HOH A O   1 
HETATM 3634 O O   . HOH G 3 .   ? 9.99164   -7.56644 -25.18274 1.000 45.13022 ? 463 HOH A O   1 
HETATM 3635 O O   . HOH G 3 .   ? -10.29821 5.87488  -27.83609 1.000 29.90633 ? 464 HOH A O   1 
HETATM 3636 O O   . HOH G 3 .   ? 28.30381  15.23533 -30.65359 1.000 44.60334 ? 465 HOH A O   1 
HETATM 3637 O O   . HOH G 3 .   ? 4.579     -3.486   -4.014    1.000 41.99637 ? 466 HOH A O   1 
HETATM 3638 O O   . HOH G 3 .   ? -0.00000  16.86937 -36.80650 0.50  36.51147 ? 467 HOH A O   1 
HETATM 3639 O O   . HOH H 3 .   ? -21.02450 35.37376 -5.77032  1.000 47.78406 ? 301 HOH B O   1 
HETATM 3640 O O   . HOH H 3 .   ? -15.26556 38.10261 -25.12313 1.000 35.84611 ? 302 HOH B O   1 
HETATM 3641 O O   . HOH H 3 .   ? 4.92877   20.49275 -8.63435  1.000 23.87919 ? 303 HOH B O   1 
HETATM 3642 O O   . HOH H 3 .   ? 17.09754  31.25028 -6.37870  1.000 31.98480 ? 304 HOH B O   1 
HETATM 3643 O O   . HOH H 3 .   ? -1.79016  20.80172 -7.63597  1.000 20.40833 ? 305 HOH B O   1 
HETATM 3644 O O   . HOH H 3 .   ? -7.02999  35.31643 1.79083   1.000 32.57578 ? 306 HOH B O   1 
HETATM 3645 O O   . HOH H 3 .   ? 4.20569   42.33067 -4.16215  1.000 36.45515 ? 307 HOH B O   1 
HETATM 3646 O O   . HOH H 3 .   ? -3.26096  25.83298 -32.83309 1.000 22.83183 ? 308 HOH B O   1 
HETATM 3647 O O   . HOH H 3 .   ? -14.10601 34.78666 -14.44486 1.000 16.68439 ? 309 HOH B O   1 
HETATM 3648 O O   . HOH H 3 .   ? -21.06016 22.31140 -24.79534 1.000 29.87589 ? 310 HOH B O   1 
HETATM 3649 O O   . HOH H 3 .   ? -9.79502  43.64105 -20.86295 1.000 29.85802 ? 311 HOH B O   1 
HETATM 3650 O O   . HOH H 3 .   ? 9.07000   41.47447 -12.46053 1.000 29.74540 ? 312 HOH B O   1 
HETATM 3651 O O   . HOH H 3 .   ? 3.26411   22.88805 -17.76228 1.000 22.79261 ? 313 HOH B O   1 
HETATM 3652 O O   . HOH H 3 .   ? -1.51344  29.32696 0.79882   1.000 31.40588 ? 314 HOH B O   1 
HETATM 3653 O O   . HOH H 3 .   ? -8.25974  17.86182 -33.72039 1.000 27.38688 ? 315 HOH B O   1 
HETATM 3654 O O   . HOH H 3 .   ? 8.01928   39.84352 -10.46616 1.000 24.68231 ? 316 HOH B O   1 
HETATM 3655 O O   . HOH H 3 .   ? -16.55407 14.63576 -5.48840  1.000 33.11932 ? 317 HOH B O   1 
HETATM 3656 O O   . HOH H 3 .   ? 7.29164   41.27172 -6.23722  1.000 31.09631 ? 318 HOH B O   1 
HETATM 3657 O O   . HOH H 3 .   ? 7.70723   35.49290 -9.14325  1.000 18.65150 ? 319 HOH B O   1 
HETATM 3658 O O   . HOH H 3 .   ? -23.35893 16.76084 -29.72764 1.000 37.06140 ? 320 HOH B O   1 
HETATM 3659 O O   . HOH H 3 .   ? -11.73785 19.54797 -20.81779 1.000 20.81920 ? 321 HOH B O   1 
HETATM 3660 O O   . HOH H 3 .   ? 3.22970   23.90593 -1.54661  1.000 23.80472 ? 322 HOH B O   1 
HETATM 3661 O O   . HOH H 3 .   ? -11.66939 40.24311 -20.10167 1.000 23.92697 ? 323 HOH B O   1 
HETATM 3662 O O   . HOH H 3 .   ? -22.11260 26.06117 -5.95096  1.000 39.07544 ? 324 HOH B O   1 
HETATM 3663 O O   . HOH H 3 .   ? -2.68819  17.80328 -34.06863 1.000 32.59793 ? 325 HOH B O   1 
HETATM 3664 O O   . HOH H 3 .   ? -8.84153  25.11286 -29.45972 1.000 12.28162 ? 326 HOH B O   1 
HETATM 3665 O O   . HOH H 3 .   ? 6.87309   23.25365 -3.76754  1.000 23.30983 ? 327 HOH B O   1 
HETATM 3666 O O   . HOH H 3 .   ? -12.13380 12.11856 -28.87427 1.000 30.60296 ? 328 HOH B O   1 
HETATM 3667 O O   . HOH H 3 .   ? -15.46532 33.67151 -10.13892 1.000 19.62256 ? 329 HOH B O   1 
HETATM 3668 O O   . HOH H 3 .   ? 3.02452   33.86838 -7.36116  1.000 11.49259 ? 330 HOH B O   1 
HETATM 3669 O O   . HOH H 3 .   ? 5.96946   33.31346 -8.93320  1.000 14.68505 ? 331 HOH B O   1 
HETATM 3670 O O   . HOH H 3 .   ? -15.02244 32.73462 -32.87370 1.000 27.43800 ? 332 HOH B O   1 
HETATM 3671 O O   . HOH H 3 .   ? -23.58630 17.78253 -27.61761 1.000 30.11377 ? 333 HOH B O   1 
HETATM 3672 O O   . HOH H 3 .   ? -8.96175  25.56505 -34.08676 1.000 24.55277 ? 334 HOH B O   1 
HETATM 3673 O O   . HOH H 3 .   ? -12.36470 41.22992 -14.05933 1.000 27.75539 ? 335 HOH B O   1 
HETATM 3674 O O   . HOH H 3 .   ? -13.63194 12.83215 -30.95578 1.000 32.70089 ? 336 HOH B O   1 
HETATM 3675 O O   . HOH H 3 .   ? -2.07083  41.60182 -3.31045  1.000 29.15382 ? 337 HOH B O   1 
HETATM 3676 O O   . HOH H 3 .   ? -23.86261 20.03352 -10.17513 1.000 28.84883 ? 338 HOH B O   1 
HETATM 3677 O O   . HOH H 3 .   ? -15.87343 9.57956  -15.82629 1.000 21.37214 ? 339 HOH B O   1 
HETATM 3678 O O   . HOH H 3 .   ? -19.60454 3.96801  -13.94364 1.000 20.62919 ? 340 HOH B O   1 
HETATM 3679 O O   . HOH H 3 .   ? -6.67010  44.55379 -18.95650 1.000 31.32690 ? 341 HOH B O   1 
HETATM 3680 O O   . HOH H 3 .   ? 8.42332   30.95797 -7.25950  1.000 14.79277 ? 342 HOH B O   1 
HETATM 3681 O O   . HOH H 3 .   ? -3.48074  42.30253 -23.08549 1.000 16.19050 ? 343 HOH B O   1 
HETATM 3682 O O   . HOH H 3 .   ? -11.94422 38.86445 -22.89289 1.000 19.01959 ? 344 HOH B O   1 
HETATM 3683 O O   . HOH H 3 .   ? -9.422    15.654   -34.328   1.000 35.74602 ? 345 HOH B O   1 
HETATM 3684 O O   . HOH H 3 .   ? -11.64542 24.44842 -11.22538 1.000 10.27020 ? 346 HOH B O   1 
HETATM 3685 O O   . HOH H 3 .   ? 7.16027   32.03576 -25.18990 1.000 18.81254 ? 347 HOH B O   1 
HETATM 3686 O O   . HOH H 3 .   ? -0.15001  33.47711 2.50205   1.000 32.28581 ? 348 HOH B O   1 
HETATM 3687 O O   . HOH H 3 .   ? -5.70407  33.26735 -30.09614 1.000 13.28873 ? 349 HOH B O   1 
HETATM 3688 O O   . HOH H 3 .   ? -20.67420 8.68510  -8.45326  1.000 23.83395 ? 350 HOH B O   1 
HETATM 3689 O O   . HOH H 3 .   ? -7.31563  24.48348 -32.94766 1.000 18.03816 ? 351 HOH B O   1 
HETATM 3690 O O   . HOH H 3 .   ? -15.75020 21.46945 -32.73084 1.000 29.09034 ? 352 HOH B O   1 
HETATM 3691 O O   . HOH H 3 .   ? -15.25487 24.46373 -32.78973 1.000 12.61617 ? 353 HOH B O   1 
HETATM 3692 O O   . HOH H 3 .   ? -10.19441 37.27475 -4.13055  1.000 30.69239 ? 354 HOH B O   1 
HETATM 3693 O O   . HOH H 3 .   ? 6.37203   39.25842 -12.39200 1.000 17.02063 ? 355 HOH B O   1 
HETATM 3694 O O   . HOH H 3 .   ? -6.77977  37.78250 -3.28977  1.000 24.55398 ? 356 HOH B O   1 
HETATM 3695 O O   . HOH H 3 .   ? -18.13109 32.71374 -26.44041 1.000 29.16849 ? 357 HOH B O   1 
HETATM 3696 O O   . HOH H 3 .   ? -13.45533 34.32407 -8.09134  1.000 17.63182 ? 358 HOH B O   1 
HETATM 3697 O O   . HOH H 3 .   ? -12.33532 32.77181 -2.06212  1.000 22.95479 ? 359 HOH B O   1 
HETATM 3698 O O   . HOH H 3 .   ? -16.08827 23.84642 -25.99707 1.000 27.94529 ? 360 HOH B O   1 
HETATM 3699 O O   . HOH H 3 .   ? -10.06191 18.43664 -30.88199 1.000 16.12604 ? 361 HOH B O   1 
HETATM 3700 O O   . HOH H 3 .   ? -22.83117 20.68288 -26.08236 1.000 25.85333 ? 362 HOH B O   1 
HETATM 3701 O O   . HOH H 3 .   ? -26.54346 10.28481 -12.15280 1.000 20.55976 ? 363 HOH B O   1 
HETATM 3702 O O   . HOH H 3 .   ? -6.94843  41.91432 -25.53451 1.000 20.99352 ? 364 HOH B O   1 
HETATM 3703 O O   . HOH H 3 .   ? -5.10546  11.96231 -31.67812 1.000 14.51067 ? 365 HOH B O   1 
HETATM 3704 O O   . HOH H 3 .   ? 1.65596   24.22542 -24.70044 1.000 10.59505 ? 366 HOH B O   1 
HETATM 3705 O O   . HOH H 3 .   ? 0.65724   25.61445 0.24826   1.000 22.04738 ? 367 HOH B O   1 
HETATM 3706 O O   . HOH H 3 .   ? -7.00565  12.75225 -33.34142 1.000 33.96094 ? 368 HOH B O   1 
HETATM 3707 O O   . HOH H 3 .   ? -15.85734 25.97029 -27.85768 1.000 28.09131 ? 369 HOH B O   1 
HETATM 3708 O O   . HOH H 3 .   ? 0.17557   20.94050 -27.97041 1.000 19.88584 ? 370 HOH B O   1 
HETATM 3709 O O   . HOH H 3 .   ? -11.24272 4.48480  -18.32555 1.000 25.32559 ? 371 HOH B O   1 
HETATM 3710 O O   . HOH H 3 .   ? 5.88503   39.35000 -15.22953 1.000 13.36555 ? 372 HOH B O   1 
HETATM 3711 O O   . HOH H 3 .   ? -15.94871 16.92116 -4.93107  1.000 32.84686 ? 373 HOH B O   1 
HETATM 3712 O O   . HOH H 3 .   ? 10.01893  33.52329 -7.64249  1.000 14.95914 ? 374 HOH B O   1 
HETATM 3713 O O   . HOH H 3 .   ? 14.05727  29.84603 -4.22928  1.000 23.60352 ? 375 HOH B O   1 
HETATM 3714 O O   . HOH H 3 .   ? -15.36926 10.24555 -26.13999 1.000 24.23037 ? 376 HOH B O   1 
HETATM 3715 O O   . HOH H 3 .   ? -13.64549 7.14041  -23.05672 1.000 19.98001 ? 377 HOH B O   1 
HETATM 3716 O O   . HOH H 3 .   ? -17.40501 35.35545 -27.21916 1.000 32.94621 ? 378 HOH B O   1 
HETATM 3717 O O   . HOH H 3 .   ? -20.04470 30.04842 -14.31183 1.000 35.20815 ? 379 HOH B O   1 
HETATM 3718 O O   . HOH H 3 .   ? 13.07780  36.17248 -4.21181  1.000 22.82441 ? 380 HOH B O   1 
HETATM 3719 O O   . HOH H 3 .   ? 0.54664   30.45319 -3.43996  1.000 15.37985 ? 381 HOH B O   1 
HETATM 3720 O O   . HOH H 3 .   ? -4.04003  25.67300 0.33025   1.000 31.32356 ? 382 HOH B O   1 
HETATM 3721 O O   . HOH H 3 .   ? -6.45494  29.04190 -34.09275 1.000 22.55479 ? 383 HOH B O   1 
HETATM 3722 O O   . HOH H 3 .   ? 16.91309  39.88887 -7.82296  1.000 27.94489 ? 384 HOH B O   1 
HETATM 3723 O O   . HOH H 3 .   ? 12.08454  31.55009 -0.70963  1.000 30.86701 ? 385 HOH B O   1 
HETATM 3724 O O   . HOH H 3 .   ? 6.93170   25.86326 -2.28372  1.000 20.21457 ? 386 HOH B O   1 
HETATM 3725 O O   . HOH H 3 .   ? -14.16563 28.89380 -31.25817 1.000 14.14227 ? 387 HOH B O   1 
HETATM 3726 O O   . HOH H 3 .   ? -19.50209 9.78658  -23.59900 1.000 22.11968 ? 388 HOH B O   1 
HETATM 3727 O O   . HOH H 3 .   ? 5.54685   27.31461 -9.60257  1.000 10.00681 ? 389 HOH B O   1 
HETATM 3728 O O   . HOH H 3 .   ? -9.51945  37.79926 -29.82997 1.000 25.51146 ? 390 HOH B O   1 
HETATM 3729 O O   . HOH H 3 .   ? 13.28238  41.16672 -8.64481  1.000 27.91017 ? 391 HOH B O   1 
HETATM 3730 O O   . HOH H 3 .   ? -16.36548 28.40311 -10.48039 1.000 24.83249 ? 392 HOH B O   1 
HETATM 3731 O O   . HOH H 3 .   ? -15.65109 24.89813 -18.11677 1.000 22.56852 ? 393 HOH B O   1 
HETATM 3732 O O   . HOH H 3 .   ? 18.98012  38.17869 -9.52081  1.000 21.63694 ? 394 HOH B O   1 
HETATM 3733 O O   . HOH H 3 .   ? -23.59815 4.08194  -13.30799 1.000 20.58590 ? 395 HOH B O   1 
HETATM 3734 O O   . HOH H 3 .   ? 7.68475   39.08315 -7.75842  1.000 20.45743 ? 396 HOH B O   1 
HETATM 3735 O O   . HOH H 3 .   ? 5.69671   34.31626 -2.09209  1.000 25.05743 ? 397 HOH B O   1 
HETATM 3736 O O   . HOH H 3 .   ? 4.24167   48.71172 -13.92148 1.000 32.12212 ? 398 HOH B O   1 
HETATM 3737 O O   . HOH H 3 .   ? 8.91491   31.09922 -0.59121  1.000 22.79885 ? 399 HOH B O   1 
HETATM 3738 O O   . HOH H 3 .   ? -14.21843 6.90349  -15.73806 1.000 26.15526 ? 400 HOH B O   1 
HETATM 3739 O O   . HOH H 3 .   ? -24.01062 18.79330 -19.46164 1.000 25.48484 ? 401 HOH B O   1 
HETATM 3740 O O   . HOH H 3 .   ? -12.34713 37.67238 -10.84761 1.000 16.40077 ? 402 HOH B O   1 
HETATM 3741 O O   . HOH H 3 .   ? -27.04091 13.73513 -15.07556 1.000 33.24584 ? 403 HOH B O   1 
HETATM 3742 O O   . HOH H 3 .   ? 10.57147  40.81048 -7.93045  1.000 23.43142 ? 404 HOH B O   1 
HETATM 3743 O O   . HOH H 3 .   ? -9.27307  26.50195 -26.94803 1.000 12.84489 ? 405 HOH B O   1 
HETATM 3744 O O   . HOH H 3 .   ? -16.43599 36.95048 -20.91323 1.000 29.40410 ? 406 HOH B O   1 
HETATM 3745 O O   . HOH H 3 .   ? -9.08210  42.79823 -6.33017  1.000 33.63200 ? 407 HOH B O   1 
HETATM 3746 O O   . HOH H 3 .   ? -17.56417 28.84883 -2.73563  1.000 31.08503 ? 408 HOH B O   1 
HETATM 3747 O O   . HOH H 3 .   ? -9.29614  8.24264  -28.90646 1.000 23.64960 ? 409 HOH B O   1 
HETATM 3748 O O   . HOH H 3 .   ? -13.50839 40.23147 -17.51372 1.000 31.56609 ? 410 HOH B O   1 
HETATM 3749 O O   . HOH H 3 .   ? -0.45810  24.11720 -29.02221 1.000 21.50102 ? 411 HOH B O   1 
HETATM 3750 O O   . HOH H 3 .   ? -5.61797  43.69632 -8.92498  1.000 31.24731 ? 412 HOH B O   1 
HETATM 3751 O O   . HOH H 3 .   ? 5.56533   31.19815 -10.83355 1.000 12.50656 ? 413 HOH B O   1 
HETATM 3752 O O   . HOH H 3 .   ? 0.77663   41.64301 -5.71756  1.000 33.24500 ? 414 HOH B O   1 
HETATM 3753 O O   . HOH H 3 .   ? -18.46769 34.57830 -12.62196 1.000 36.07999 ? 415 HOH B O   1 
HETATM 3754 O O   . HOH H 3 .   ? -19.32545 34.08222 -17.78965 1.000 30.88920 ? 416 HOH B O   1 
HETATM 3755 O O   . HOH H 3 .   ? 0.75191   43.31486 -8.02628  1.000 20.68315 ? 417 HOH B O   1 
HETATM 3756 O O   . HOH H 3 .   ? -19.37085 31.66395 -16.20835 1.000 27.34602 ? 418 HOH B O   1 
HETATM 3757 O O   . HOH H 3 .   ? -4.14227  37.28521 -3.08045  1.000 23.35895 ? 419 HOH B O   1 
HETATM 3758 O O   . HOH H 3 .   ? -16.42221 24.79111 -3.19499  1.000 25.56009 ? 420 HOH B O   1 
HETATM 3759 O O   . HOH H 3 .   ? -7.54252  31.69830 3.31310   1.000 20.14639 ? 421 HOH B O   1 
HETATM 3760 O O   . HOH H 3 .   ? -8.97912  26.49317 -0.82055  1.000 25.12019 ? 422 HOH B O   1 
HETATM 3761 O O   . HOH H 3 .   ? 3.19907   45.05031 -8.47486  1.000 31.75501 ? 423 HOH B O   1 
HETATM 3762 O O   . HOH H 3 .   ? 18.29797  38.28136 -5.77000  1.000 41.06148 ? 424 HOH B O   1 
HETATM 3763 O O   . HOH H 3 .   ? -15.54583 4.27939  -19.86036 1.000 36.02867 ? 425 HOH B O   1 
HETATM 3764 O O   . HOH H 3 .   ? -10.10431 39.91600 -2.80443  1.000 36.71839 ? 426 HOH B O   1 
HETATM 3765 O O   . HOH H 3 .   ? -3.47064  35.68795 -0.89411  1.000 21.62094 ? 427 HOH B O   1 
HETATM 3766 O O   . HOH H 3 .   ? -21.28074 2.40781  -12.81182 1.000 29.18104 ? 428 HOH B O   1 
HETATM 3767 O O   . HOH H 3 .   ? -16.90941 10.48845 -13.41813 1.000 19.53157 ? 429 HOH B O   1 
HETATM 3768 O O   . HOH H 3 .   ? -15.80461 38.35620 -15.12272 1.000 30.96543 ? 430 HOH B O   1 
HETATM 3769 O O   . HOH H 3 .   ? -14.68694 34.72419 -34.71597 1.000 29.97113 ? 431 HOH B O   1 
HETATM 3770 O O   . HOH H 3 .   ? -3.57405  45.61605 -13.51832 1.000 21.77869 ? 432 HOH B O   1 
HETATM 3771 O O   . HOH H 3 .   ? -28.48922 16.11373 -12.18483 1.000 36.68762 ? 433 HOH B O   1 
HETATM 3772 O O   . HOH H 3 .   ? -15.59836 30.85390 -32.02861 1.000 33.56168 ? 434 HOH B O   1 
HETATM 3773 O O   . HOH H 3 .   ? -16.33536 30.96116 -2.87640  1.000 30.54109 ? 435 HOH B O   1 
HETATM 3774 O O   . HOH H 3 .   ? -23.29556 7.65892  -7.30832  1.000 36.69403 ? 436 HOH B O   1 
HETATM 3775 O O   . HOH H 3 .   ? -11.50063 37.82561 -35.16648 1.000 36.49487 ? 437 HOH B O   1 
HETATM 3776 O O   . HOH H 3 .   ? 4.96487   22.84403 -2.83177  1.000 30.33407 ? 438 HOH B O   1 
HETATM 3777 O O   . HOH H 3 .   ? -6.38875  36.50348 -31.86365 1.000 29.20283 ? 439 HOH B O   1 
HETATM 3778 O O   . HOH H 3 .   ? -8.26480  36.83016 -33.27513 1.000 28.79504 ? 440 HOH B O   1 
HETATM 3779 O O   . HOH H 3 .   ? -0.49827  44.28356 -6.08627  1.000 41.67246 ? 441 HOH B O   1 
HETATM 3780 O O   . HOH H 3 .   ? -13.68220 31.99974 -3.75907  1.000 24.51737 ? 442 HOH B O   1 
HETATM 3781 O O   . HOH H 3 .   ? -20.67309 10.92782 -6.86669  1.000 25.22123 ? 443 HOH B O   1 
HETATM 3782 O O   . HOH H 3 .   ? -14.51227 34.13260 -5.60838  1.000 24.30412 ? 444 HOH B O   1 
HETATM 3783 O O   . HOH H 3 .   ? 16.62045  30.61485 -4.25693  1.000 32.77864 ? 445 HOH B O   1 
HETATM 3784 O O   . HOH H 3 .   ? 1.62795   23.98534 1.65498   1.000 37.09350 ? 446 HOH B O   1 
HETATM 3785 O O   . HOH H 3 .   ? -13.52160 39.85829 -12.05903 1.000 29.29797 ? 447 HOH B O   1 
HETATM 3786 O O   . HOH H 3 .   ? 0.10404   46.54613 -17.01645 1.000 32.70721 ? 448 HOH B O   1 
HETATM 3787 O O   . HOH H 3 .   ? -1.50577  18.37081 -7.35686  1.000 16.35154 ? 449 HOH B O   1 
HETATM 3788 O O   . HOH H 3 .   ? -12.35725 35.78879 -1.89070  1.000 34.41467 ? 450 HOH B O   1 
HETATM 3789 O O   . HOH H 3 .   ? -11.72563 40.16971 -29.30396 1.000 37.45860 ? 451 HOH B O   1 
HETATM 3790 O O   . HOH H 3 .   ? -8.25934  39.13238 -28.12799 1.000 36.89131 ? 452 HOH B O   1 
HETATM 3791 O O   . HOH H 3 .   ? -2.89761  47.24498 -14.98220 1.000 36.58029 ? 453 HOH B O   1 
HETATM 3792 O O   . HOH H 3 .   ? 0.10939   21.70936 -25.49200 1.000 16.10533 ? 454 HOH B O   1 
HETATM 3793 O O   . HOH H 3 .   ? -15.48275 27.66727 -29.26768 1.000 31.29034 ? 455 HOH B O   1 
HETATM 3794 O O   . HOH H 3 .   ? -29.460   10.425   -22.640   1.000 35.21585 ? 456 HOH B O   1 
HETATM 3795 O O   . HOH H 3 .   ? -14.63484 35.84301 -12.03790 1.000 25.65333 ? 457 HOH B O   1 
HETATM 3796 O O   . HOH H 3 .   ? 8.41834   42.54103 -9.43218  1.000 32.28003 ? 458 HOH B O   1 
HETATM 3797 O O   . HOH H 3 .   ? -17.18975 8.11029  -11.77282 1.000 25.13716 ? 459 HOH B O   1 
HETATM 3798 O O   . HOH H 3 .   ? -23.00376 11.93624 -5.97741  1.000 35.06716 ? 460 HOH B O   1 
HETATM 3799 O O   . HOH H 3 .   ? -20.30943 33.16465 -13.72224 1.000 40.68365 ? 461 HOH B O   1 
HETATM 3800 O O   . HOH H 3 .   ? 8.36294   26.63018 -0.27396  1.000 27.33091 ? 462 HOH B O   1 
HETATM 3801 O O   . HOH H 3 .   ? -24.13871 21.17573 -20.93601 1.000 30.26170 ? 463 HOH B O   1 
HETATM 3802 O O   . HOH H 3 .   ? -17.444   3.073    -15.427   1.000 25.62844 ? 464 HOH B O   1 
HETATM 3803 O O   . HOH H 3 .   ? -4.35752  46.01824 -10.87362 1.000 33.90784 ? 465 HOH B O   1 
HETATM 3804 O O   . HOH H 3 .   ? 3.27796   22.76562 0.73880   1.000 29.22743 ? 466 HOH B O   1 
HETATM 3805 O O   . HOH H 3 .   ? -15.70941 26.43811 -30.90978 1.000 22.93459 ? 467 HOH B O   1 
HETATM 3806 O O   . HOH H 3 .   ? -16.61549 11.44371 -28.23366 1.000 35.68096 ? 468 HOH B O   1 
HETATM 3807 O O   . HOH H 3 .   ? 4.13713   36.57158 -1.87262  1.000 30.04696 ? 469 HOH B O   1 
HETATM 3808 O O   . HOH H 3 .   ? 7.13558   25.32962 1.92610   1.000 32.82808 ? 470 HOH B O   1 
HETATM 3809 O O   . HOH H 3 .   ? -1.45255  23.90593 1.45022   1.000 33.51004 ? 471 HOH B O   1 
HETATM 3810 O O   . HOH H 3 .   ? -9.46669  40.51624 -26.29816 1.000 33.44359 ? 472 HOH B O   1 
HETATM 3811 O O   . HOH H 3 .   ? -0.92076  35.93698 3.04962   1.000 36.55154 ? 473 HOH B O   1 
HETATM 3812 O O   . HOH H 3 .   ? -14.38987 6.82597  -25.64378 1.000 33.33965 ? 474 HOH B O   1 
HETATM 3813 O O   . HOH H 3 .   ? -1.51847  31.12911 3.17592   1.000 29.98366 ? 475 HOH B O   1 
HETATM 3814 O O   . HOH H 3 .   ? -12.94063 37.02678 -8.37748  1.000 27.26559 ? 476 HOH B O   1 
HETATM 3815 O O   . HOH H 3 .   ? 7.43162   35.11198 -0.49615  1.000 37.98049 ? 477 HOH B O   1 
HETATM 3816 O O   . HOH H 3 .   ? -10.74264 43.56048 -23.10986 1.000 36.76598 ? 478 HOH B O   1 
HETATM 3817 O O   . HOH H 3 .   ? 1.01831   49.15685 -15.76860 1.000 35.30988 ? 479 HOH B O   1 
HETATM 3818 O O   . HOH H 3 .   ? -5.64932  23.22364 -34.76388 1.000 26.72647 ? 480 HOH B O   1 
HETATM 3819 O O   . HOH H 3 .   ? -8.90457  44.24605 -24.61635 1.000 43.01636 ? 481 HOH B O   1 
HETATM 3820 O O   . HOH H 3 .   ? -14.88600 38.26676 -22.38961 1.000 29.31672 ? 482 HOH B O   1 
HETATM 3821 O O   . HOH H 3 .   ? -11.86629 9.28317  -28.78210 1.000 26.10940 ? 483 HOH B O   1 
HETATM 3822 O O   . HOH H 3 .   ? -11.33281 40.83404 -24.69854 1.000 26.89637 ? 484 HOH B O   1 
HETATM 3823 O O   . HOH H 3 .   ? -14.20451 8.33337  -27.55050 1.000 28.52988 ? 485 HOH B O   1 
HETATM 3824 O O   . HOH H 3 .   ? -2.63327  46.81702 -17.30812 1.000 35.38248 ? 486 HOH B O   1 
HETATM 3825 O O   . HOH H 3 .   ? -5.81061  41.56581 -27.77708 1.000 29.89315 ? 487 HOH B O   1 
HETATM 3826 O O   . HOH H 3 .   ? 8.75238   28.87701 0.84469   1.000 23.56490 ? 488 HOH B O   1 
HETATM 3827 O O   . HOH H 3 .   ? 20.327    34.206   -2.188    1.000 34.95355 ? 489 HOH B O   1 
HETATM 3828 O O   . HOH H 3 .   ? -18.676   21.300   -1.987    1.000 32.48394 ? 490 HOH B O   1 
HETATM 3829 O O   . HOH H 3 .   ? -2.78992  36.91507 3.81554   1.000 44.67583 ? 491 HOH B O   1 
HETATM 3830 O O   . HOH H 3 .   ? 3.91963   48.04131 -6.05939  1.000 49.06196 ? 492 HOH B O   1 
HETATM 3831 O O   . HOH H 3 .   ? -16.218   10.696   -33.196   1.000 34.47422 ? 493 HOH B O   1 
HETATM 3832 O O   . HOH H 3 .   ? -10.30026 42.02991 -28.44539 1.000 37.75616 ? 494 HOH B O   1 
HETATM 3833 O O   . HOH H 3 .   ? -15.84073 37.66395 -8.54856  1.000 35.26841 ? 495 HOH B O   1 
HETATM 3834 O O   . HOH H 3 .   ? -7.98928  43.60949 -29.39736 1.000 48.78457 ? 496 HOH B O   1 
HETATM 3835 O O   . HOH I 3 .   ? 29.56289  14.71853 -23.20031 1.000 38.56496 ? 301 HOH C O   1 
HETATM 3836 O O   . HOH I 3 .   ? -2.35217  45.44284 -26.86193 1.000 40.41523 ? 302 HOH C O   1 
HETATM 3837 O O   . HOH I 3 .   ? 17.20466  43.70372 -23.76823 1.000 35.51215 ? 303 HOH C O   1 
HETATM 3838 O O   . HOH I 3 .   ? 24.34279  28.49678 -33.55438 1.000 33.42313 ? 304 HOH C O   1 
HETATM 3839 O O   . HOH I 3 .   ? 14.45635  23.26433 0.13206   1.000 30.57345 ? 305 HOH C O   1 
HETATM 3840 O O   . HOH I 3 .   ? 0.54262   52.94129 -14.90994 1.000 42.44356 ? 306 HOH C O   1 
HETATM 3841 O O   . HOH I 3 .   ? 9.21393   28.45625 -9.84542  1.000 20.26390 ? 307 HOH C O   1 
HETATM 3842 O O   . HOH I 3 .   ? 17.018    18.407   0.292     1.000 29.47915 ? 308 HOH C O   1 
HETATM 3843 O O   . HOH I 3 .   ? 5.63933   22.94700 -8.76748  1.000 20.76241 ? 309 HOH C O   1 
HETATM 3844 O O   . HOH I 3 .   ? 2.48221   24.38890 -32.85922 1.000 23.93727 ? 310 HOH C O   1 
HETATM 3845 O O   . HOH I 3 .   ? -1.34179  38.28232 -35.67558 1.000 36.79600 ? 311 HOH C O   1 
HETATM 3846 O O   . HOH I 3 .   ? 2.30535   54.36761 -18.95893 1.000 22.72631 ? 312 HOH C O   1 
HETATM 3847 O O   . HOH I 3 .   ? 17.26383  44.83660 -27.95664 1.000 41.69915 ? 313 HOH C O   1 
HETATM 3848 O O   . HOH I 3 .   ? 23.78908  19.14995 -31.86555 1.000 25.85871 ? 314 HOH C O   1 
HETATM 3849 O O   . HOH I 3 .   ? 29.08432  26.17308 -22.96447 1.000 28.36261 ? 315 HOH C O   1 
HETATM 3850 O O   . HOH I 3 .   ? 18.28566  18.01301 -10.54910 1.000 12.57097 ? 316 HOH C O   1 
HETATM 3851 O O   . HOH I 3 .   ? 3.631     57.866   -20.135   1.000 26.29517 ? 317 HOH C O   1 
HETATM 3852 O O   . HOH I 3 .   ? 20.48606  8.09445  -15.03867 1.000 31.26039 ? 318 HOH C O   1 
HETATM 3853 O O   . HOH I 3 .   ? 6.33600   22.87915 -35.01856 1.000 22.93735 ? 319 HOH C O   1 
HETATM 3854 O O   . HOH I 3 .   ? 16.80360  12.90359 -11.02018 1.000 17.86807 ? 320 HOH C O   1 
HETATM 3855 O O   . HOH I 3 .   ? 26.26337  24.92434 -28.11715 1.000 27.97842 ? 321 HOH C O   1 
HETATM 3856 O O   . HOH I 3 .   ? 6.30990   50.17401 -32.55367 1.000 40.91361 ? 322 HOH C O   1 
HETATM 3857 O O   . HOH I 3 .   ? 5.73271   21.90690 -18.43292 1.000 21.22211 ? 323 HOH C O   1 
HETATM 3858 O O   . HOH I 3 .   ? 13.75946  40.98813 -32.52113 1.000 33.10386 ? 324 HOH C O   1 
HETATM 3859 O O   . HOH I 3 .   ? 27.05298  27.25170 -5.79269  1.000 31.89964 ? 325 HOH C O   1 
HETATM 3860 O O   . HOH I 3 .   ? 27.95215  21.16802 -28.75411 1.000 26.50088 ? 326 HOH C O   1 
HETATM 3861 O O   . HOH I 3 .   ? 4.78121   21.45037 -14.49347 1.000 8.44290  ? 327 HOH C O   1 
HETATM 3862 O O   . HOH I 3 .   ? 13.42270  46.25619 -27.33321 1.000 28.52762 ? 328 HOH C O   1 
HETATM 3863 O O   . HOH I 3 .   ? 8.23666   27.46639 -37.79136 1.000 22.89595 ? 329 HOH C O   1 
HETATM 3864 O O   . HOH I 3 .   ? 8.45359   35.33137 -25.09681 1.000 22.58518 ? 330 HOH C O   1 
HETATM 3865 O O   . HOH I 3 .   ? 28.25575  19.37230 -26.52928 1.000 35.09645 ? 331 HOH C O   1 
HETATM 3866 O O   . HOH I 3 .   ? 24.20789  35.05830 -8.33806  1.000 35.30159 ? 332 HOH C O   1 
HETATM 3867 O O   . HOH I 3 .   ? 0.52894   38.11285 -33.80151 1.000 32.24169 ? 333 HOH C O   1 
HETATM 3868 O O   . HOH I 3 .   ? 0.86768   27.54272 -37.32706 1.000 30.33078 ? 334 HOH C O   1 
HETATM 3869 O O   . HOH I 3 .   ? 17.42586  28.92568 -39.82226 1.000 27.40281 ? 335 HOH C O   1 
HETATM 3870 O O   . HOH I 3 .   ? 14.69401  12.19728 -8.67372  1.000 16.25315 ? 336 HOH C O   1 
HETATM 3871 O O   . HOH I 3 .   ? 20.03849  22.79935 -36.02188 1.000 24.85859 ? 337 HOH C O   1 
HETATM 3872 O O   . HOH I 3 .   ? 20.47200  40.07104 -11.17399 1.000 34.16457 ? 338 HOH C O   1 
HETATM 3873 O O   . HOH I 3 .   ? 2.23502   23.16867 -28.54977 1.000 20.07734 ? 339 HOH C O   1 
HETATM 3874 O O   . HOH I 3 .   ? 20.08146  10.29106 -12.25571 1.000 34.17872 ? 340 HOH C O   1 
HETATM 3875 O O   . HOH I 3 .   ? 9.21754   28.49753 -33.30789 1.000 11.36366 ? 341 HOH C O   1 
HETATM 3876 O O   . HOH I 3 .   ? 13.54666  14.90954 -8.28719  1.000 13.77399 ? 342 HOH C O   1 
HETATM 3877 O O   . HOH I 3 .   ? 25.59775  32.64206 -10.30932 1.000 26.27440 ? 343 HOH C O   1 
HETATM 3878 O O   . HOH I 3 .   ? -0.22741  37.96992 -31.41710 1.000 25.23163 ? 344 HOH C O   1 
HETATM 3879 O O   . HOH I 3 .   ? 0.40695   50.95747 -18.06623 1.000 23.07629 ? 345 HOH C O   1 
HETATM 3880 O O   . HOH I 3 .   ? 10.88670  18.84285 -10.65906 1.000 12.20289 ? 346 HOH C O   1 
HETATM 3881 O O   . HOH I 3 .   ? 23.44436  16.52421 -28.85574 1.000 23.44616 ? 347 HOH C O   1 
HETATM 3882 O O   . HOH I 3 .   ? 14.56147  21.68965 -34.37243 1.000 15.09902 ? 348 HOH C O   1 
HETATM 3883 O O   . HOH I 3 .   ? 24.22205  30.92556 -22.69234 1.000 17.09682 ? 349 HOH C O   1 
HETATM 3884 O O   . HOH I 3 .   ? 8.47257   35.61895 -37.80785 1.000 23.98751 ? 350 HOH C O   1 
HETATM 3885 O O   . HOH I 3 .   ? 14.09543  42.13415 -29.89792 1.000 27.04300 ? 351 HOH C O   1 
HETATM 3886 O O   . HOH I 3 .   ? 18.34579  27.55425 -41.60677 1.000 32.58018 ? 352 HOH C O   1 
HETATM 3887 O O   . HOH I 3 .   ? 13.01179  50.57764 -15.83013 1.000 24.10248 ? 353 HOH C O   1 
HETATM 3888 O O   . HOH I 3 .   ? 27.63803  19.45393 -9.68109  1.000 29.80263 ? 354 HOH C O   1 
HETATM 3889 O O   . HOH I 3 .   ? 11.00221  11.10989 -3.73914  1.000 23.67056 ? 355 HOH C O   1 
HETATM 3890 O O   . HOH I 3 .   ? 6.40151   50.48715 -14.15456 1.000 23.68069 ? 356 HOH C O   1 
HETATM 3891 O O   . HOH I 3 .   ? 5.26003   34.12948 -37.57051 1.000 24.63935 ? 357 HOH C O   1 
HETATM 3892 O O   . HOH I 3 .   ? 12.66021  43.51220 -33.20346 1.000 27.64116 ? 358 HOH C O   1 
HETATM 3893 O O   . HOH I 3 .   ? 16.05322  15.48427 -11.02960 1.000 16.54874 ? 359 HOH C O   1 
HETATM 3894 O O   . HOH I 3 .   ? 12.46125  48.72778 -31.95012 1.000 33.20734 ? 360 HOH C O   1 
HETATM 3895 O O   . HOH I 3 .   ? 8.41022   53.88898 -27.17276 1.000 30.84991 ? 361 HOH C O   1 
HETATM 3896 O O   . HOH I 3 .   ? 25.09232  30.78720 -29.96111 1.000 32.96154 ? 362 HOH C O   1 
HETATM 3897 O O   . HOH I 3 .   ? -3.86183  42.60832 -19.72509 1.000 22.04047 ? 363 HOH C O   1 
HETATM 3898 O O   . HOH I 3 .   ? 13.30943  42.88321 -11.10689 1.000 32.23808 ? 364 HOH C O   1 
HETATM 3899 O O   . HOH I 3 .   ? 2.71279   46.37925 -28.52347 1.000 21.60746 ? 365 HOH C O   1 
HETATM 3900 O O   . HOH I 3 .   ? 19.64684  11.50715 -15.11913 1.000 19.43214 ? 366 HOH C O   1 
HETATM 3901 O O   . HOH I 3 .   ? 5.30246   21.46753 -11.85820 1.000 11.06116 ? 367 HOH C O   1 
HETATM 3902 O O   . HOH I 3 .   ? 0.52358   42.01433 -29.54444 1.000 24.04701 ? 368 HOH C O   1 
HETATM 3903 O O   . HOH I 3 .   ? 20.60954  33.45562 -34.55769 1.000 30.45373 ? 369 HOH C O   1 
HETATM 3904 O O   . HOH I 3 .   ? 12.95425  48.54535 -28.76998 1.000 34.18518 ? 370 HOH C O   1 
HETATM 3905 O O   . HOH I 3 .   ? -4.77982  37.28613 -29.84145 1.000 17.29671 ? 371 HOH C O   1 
HETATM 3906 O O   . HOH I 3 .   ? 6.76947   26.88612 -35.85858 1.000 19.22939 ? 372 HOH C O   1 
HETATM 3907 O O   . HOH I 3 .   ? -4.30404  31.47865 -31.86715 1.000 12.44507 ? 373 HOH C O   1 
HETATM 3908 O O   . HOH I 3 .   ? 28.12526  28.00983 -12.40021 1.000 32.91249 ? 374 HOH C O   1 
HETATM 3909 O O   . HOH I 3 .   ? 5.35136   20.87959 -25.44950 1.000 16.65001 ? 375 HOH C O   1 
HETATM 3910 O O   . HOH I 3 .   ? 27.11423  28.26225 -19.10663 1.000 26.81624 ? 376 HOH C O   1 
HETATM 3911 O O   . HOH I 3 .   ? 27.80820  27.27543 -26.10339 1.000 33.58450 ? 377 HOH C O   1 
HETATM 3912 O O   . HOH I 3 .   ? 24.25316  30.40905 -3.82415  1.000 27.00117 ? 378 HOH C O   1 
HETATM 3913 O O   . HOH I 3 .   ? 17.12381  24.79216 -2.73342  1.000 30.63341 ? 379 HOH C O   1 
HETATM 3914 O O   . HOH I 3 .   ? 13.36186  34.30255 -34.25872 1.000 23.47564 ? 380 HOH C O   1 
HETATM 3915 O O   . HOH I 3 .   ? 14.46797  1.91953  -9.00846  1.000 24.38135 ? 381 HOH C O   1 
HETATM 3916 O O   . HOH I 3 .   ? 24.24378  25.50497 -30.62687 1.000 21.19726 ? 382 HOH C O   1 
HETATM 3917 O O   . HOH I 3 .   ? 27.06706  25.33105 -10.51139 1.000 28.58372 ? 383 HOH C O   1 
HETATM 3918 O O   . HOH I 3 .   ? 0.26006   49.22690 -25.33790 1.000 28.42781 ? 384 HOH C O   1 
HETATM 3919 O O   . HOH I 3 .   ? 15.41855  34.50160 -16.96711 1.000 11.66012 ? 385 HOH C O   1 
HETATM 3920 O O   . HOH I 3 .   ? 10.03510  23.70935 -37.57446 1.000 17.18154 ? 386 HOH C O   1 
HETATM 3921 O O   . HOH I 3 .   ? 20.51202  7.98707  -10.19226 1.000 27.80470 ? 387 HOH C O   1 
HETATM 3922 O O   . HOH I 3 .   ? 20.57017  11.50439 -10.49038 1.000 23.72068 ? 388 HOH C O   1 
HETATM 3923 O O   . HOH I 3 .   ? 29.63394  20.45749 -16.47558 1.000 27.08049 ? 389 HOH C O   1 
HETATM 3924 O O   . HOH I 3 .   ? 3.55963   32.61735 -33.77949 1.000 11.74419 ? 390 HOH C O   1 
HETATM 3925 O O   . HOH I 3 .   ? 11.80402  23.92540 -3.33308  1.000 23.85316 ? 391 HOH C O   1 
HETATM 3926 O O   . HOH I 3 .   ? 14.51719  25.82783 -2.83176  1.000 29.12891 ? 392 HOH C O   1 
HETATM 3927 O O   . HOH I 3 .   ? 19.31009  11.50785 -18.05880 1.000 17.54093 ? 393 HOH C O   1 
HETATM 3928 O O   . HOH I 3 .   ? 3.28587   44.66945 -19.92817 1.000 23.14560 ? 394 HOH C O   1 
HETATM 3929 O O   . HOH I 3 .   ? 12.39255  36.16342 -31.96733 1.000 20.61890 ? 395 HOH C O   1 
HETATM 3930 O O   . HOH I 3 .   ? 10.43659  33.69055 -38.24249 1.000 10.95823 ? 396 HOH C O   1 
HETATM 3931 O O   . HOH I 3 .   ? 17.58403  22.74896 -7.13161  1.000 14.77860 ? 397 HOH C O   1 
HETATM 3932 O O   . HOH I 3 .   ? 25.64286  32.72705 -20.49892 1.000 35.62832 ? 398 HOH C O   1 
HETATM 3933 O O   . HOH I 3 .   ? 27.78829  30.13952 -24.69568 1.000 27.18088 ? 399 HOH C O   1 
HETATM 3934 O O   . HOH I 3 .   ? 25.57057  31.59283 -16.52257 1.000 22.80223 ? 400 HOH C O   1 
HETATM 3935 O O   . HOH I 3 .   ? 24.49085  23.47298 -7.00332  1.000 21.94347 ? 401 HOH C O   1 
HETATM 3936 O O   . HOH I 3 .   ? 19.05421  16.87642 -4.58568  1.000 32.04172 ? 402 HOH C O   1 
HETATM 3937 O O   . HOH I 3 .   ? 14.01431  36.96051 -34.70743 1.000 30.96483 ? 403 HOH C O   1 
HETATM 3938 O O   . HOH I 3 .   ? 28.99335  21.87017 -22.42150 1.000 24.59686 ? 404 HOH C O   1 
HETATM 3939 O O   . HOH I 3 .   ? 11.32024  28.71164 -31.39511 1.000 12.14750 ? 405 HOH C O   1 
HETATM 3940 O O   . HOH I 3 .   ? 17.73038  28.05758 -3.82867  1.000 28.74106 ? 406 HOH C O   1 
HETATM 3941 O O   . HOH I 3 .   ? 14.18426  41.85604 -36.04766 1.000 34.06200 ? 407 HOH C O   1 
HETATM 3942 O O   . HOH I 3 .   ? 27.14451  12.54783 -13.52695 1.000 31.13285 ? 408 HOH C O   1 
HETATM 3943 O O   . HOH I 3 .   ? 10.39131  45.15756 -34.48846 1.000 25.15853 ? 409 HOH C O   1 
HETATM 3944 O O   . HOH I 3 .   ? 1.63662   31.06711 -35.93328 1.000 30.52178 ? 410 HOH C O   1 
HETATM 3945 O O   . HOH I 3 .   ? 19.63302  5.69355  -10.32495 1.000 26.74994 ? 411 HOH C O   1 
HETATM 3946 O O   . HOH I 3 .   ? 26.49234  35.20631 -22.50162 1.000 36.61023 ? 412 HOH C O   1 
HETATM 3947 O O   . HOH I 3 .   ? 0.19337   44.52068 -18.64874 1.000 27.18646 ? 413 HOH C O   1 
HETATM 3948 O O   . HOH I 3 .   ? 14.18324  30.82149 -37.33166 1.000 12.38178 ? 414 HOH C O   1 
HETATM 3949 O O   . HOH I 3 .   ? 4.11156   43.22854 -34.60030 1.000 33.80231 ? 415 HOH C O   1 
HETATM 3950 O O   . HOH I 3 .   ? -1.64583  48.44106 -21.49498 1.000 25.84949 ? 416 HOH C O   1 
HETATM 3951 O O   . HOH I 3 .   ? 18.211    24.328   1.268     1.000 21.58719 ? 417 HOH C O   1 
HETATM 3952 O O   . HOH I 3 .   ? -1.99704  42.70802 -25.63741 1.000 16.72201 ? 418 HOH C O   1 
HETATM 3953 O O   . HOH I 3 .   ? 13.86484  16.60716 -12.55420 1.000 14.46438 ? 419 HOH C O   1 
HETATM 3954 O O   . HOH I 3 .   ? 26.51947  15.54895 -25.22772 1.000 35.22244 ? 420 HOH C O   1 
HETATM 3955 O O   . HOH I 3 .   ? 15.04314  36.29907 -24.67616 1.000 23.90755 ? 421 HOH C O   1 
HETATM 3956 O O   . HOH I 3 .   ? 5.02160   21.98223 -30.39131 1.000 21.17702 ? 422 HOH C O   1 
HETATM 3957 O O   . HOH I 3 .   ? 27.01175  15.15212 -13.47108 1.000 26.41789 ? 423 HOH C O   1 
HETATM 3958 O O   . HOH I 3 .   ? 3.06867   53.71724 -32.82649 1.000 39.36189 ? 424 HOH C O   1 
HETATM 3959 O O   . HOH I 3 .   ? 29.77441  15.93927 -15.73814 1.000 33.32240 ? 425 HOH C O   1 
HETATM 3960 O O   . HOH I 3 .   ? 5.13498   45.43037 -17.94649 1.000 19.29883 ? 426 HOH C O   1 
HETATM 3961 O O   . HOH I 3 .   ? 13.40718  51.78586 -24.17605 1.000 30.57550 ? 427 HOH C O   1 
HETATM 3962 O O   . HOH I 3 .   ? 29.00068  16.89055 -20.13233 1.000 29.64069 ? 428 HOH C O   1 
HETATM 3963 O O   . HOH I 3 .   ? 22.18943  31.26307 -35.76342 1.000 27.44492 ? 429 HOH C O   1 
HETATM 3964 O O   . HOH I 3 .   ? 14.59980  12.94524 -1.21130  1.000 27.60698 ? 430 HOH C O   1 
HETATM 3965 O O   . HOH I 3 .   ? 17.09681  47.40983 -19.37815 1.000 26.93658 ? 431 HOH C O   1 
HETATM 3966 O O   . HOH I 3 .   ? 25.13350  35.05635 -27.96399 1.000 36.17956 ? 432 HOH C O   1 
HETATM 3967 O O   . HOH I 3 .   ? 9.61129   22.74555 -4.06226  1.000 23.38451 ? 433 HOH C O   1 
HETATM 3968 O O   . HOH I 3 .   ? 25.56959  23.23316 -9.05755  1.000 28.69894 ? 434 HOH C O   1 
HETATM 3969 O O   . HOH I 3 .   ? 16.38978  33.93027 -35.32374 1.000 28.65919 ? 435 HOH C O   1 
HETATM 3970 O O   . HOH I 3 .   ? -3.50930  32.21202 -34.18295 1.000 26.44173 ? 436 HOH C O   1 
HETATM 3971 O O   . HOH I 3 .   ? 0.18083   53.36995 -17.07419 1.000 28.87745 ? 437 HOH C O   1 
HETATM 3972 O O   . HOH I 3 .   ? 25.25909  9.78953  -12.74280 1.000 37.05037 ? 438 HOH C O   1 
HETATM 3973 O O   . HOH I 3 .   ? 16.33741  30.87390 -39.10397 1.000 28.00697 ? 439 HOH C O   1 
HETATM 3974 O O   . HOH I 3 .   ? 29.77561  18.02352 -14.73740 1.000 33.15726 ? 440 HOH C O   1 
HETATM 3975 O O   . HOH I 3 .   ? 7.02929   18.36446 -3.37758  1.000 31.29286 ? 441 HOH C O   1 
HETATM 3976 O O   . HOH I 3 .   ? 27.09150  21.37026 -8.44296  1.000 36.53426 ? 442 HOH C O   1 
HETATM 3977 O O   . HOH I 3 .   ? 3.865     32.054   -37.210   1.000 30.18099 ? 443 HOH C O   1 
HETATM 3978 O O   . HOH I 3 .   ? -4.02961  44.86598 -23.01159 1.000 31.34692 ? 444 HOH C O   1 
HETATM 3979 O O   . HOH I 3 .   ? 24.340    18.015   -5.036    1.000 24.92837 ? 445 HOH C O   1 
HETATM 3980 O O   . HOH I 3 .   ? 7.17699   29.64656 -9.13931  1.000 12.35186 ? 446 HOH C O   1 
HETATM 3981 O O   . HOH I 3 .   ? -0.00000  32.51249 -36.80650 0.50  28.66614 ? 447 HOH C O   1 
HETATM 3982 O O   . HOH I 3 .   ? 0.70790   44.68293 -28.21134 1.000 26.44572 ? 448 HOH C O   1 
HETATM 3983 O O   . HOH I 3 .   ? 2.43020   46.58715 -31.63981 1.000 32.74628 ? 449 HOH C O   1 
HETATM 3984 O O   . HOH I 3 .   ? 29.35933  25.21764 -26.72786 1.000 38.21942 ? 450 HOH C O   1 
HETATM 3985 O O   . HOH I 3 .   ? 3.94942   24.03475 -34.84339 1.000 33.89247 ? 451 HOH C O   1 
HETATM 3986 O O   . HOH I 3 .   ? 16.990    49.990   -19.225   1.000 37.18133 ? 452 HOH C O   1 
HETATM 3987 O O   . HOH I 3 .   ? 26.83393  19.45713 -5.52729  1.000 29.93349 ? 453 HOH C O   1 
HETATM 3988 O O   . HOH I 3 .   ? 15.25964  39.45943 -34.45286 1.000 35.24239 ? 454 HOH C O   1 
HETATM 3989 O O   . HOH I 3 .   ? 12.27616  16.40077 -10.18067 1.000 16.32337 ? 455 HOH C O   1 
HETATM 3990 O O   . HOH I 3 .   ? 22.34641  22.31445 -34.43304 1.000 34.93189 ? 456 HOH C O   1 
HETATM 3991 O O   . HOH I 3 .   ? 29.07817  28.15192 -20.93447 1.000 31.71250 ? 457 HOH C O   1 
HETATM 3992 O O   . HOH I 3 .   ? 8.54882   49.64935 -12.75020 1.000 31.21702 ? 458 HOH C O   1 
HETATM 3993 O O   . HOH I 3 .   ? 27.77344  33.46439 -28.27479 1.000 34.84758 ? 459 HOH C O   1 
HETATM 3994 O O   . HOH I 3 .   ? 27.50550  10.46892 -12.75974 1.000 43.69484 ? 460 HOH C O   1 
HETATM 3995 O O   . HOH I 3 .   ? 20.22426  36.48371 -7.95233  1.000 33.61459 ? 461 HOH C O   1 
HETATM 3996 O O   . HOH I 3 .   ? 3.39968   47.08419 -16.21114 1.000 26.37587 ? 462 HOH C O   1 
HETATM 3997 O O   . HOH I 3 .   ? 3.67950   23.29453 -26.06329 1.000 17.27773 ? 463 HOH C O   1 
HETATM 3998 O O   . HOH I 3 .   ? 27.65881  29.40778 -16.86288 1.000 31.31656 ? 464 HOH C O   1 
HETATM 3999 O O   . HOH I 3 .   ? 4.334     30.072   -38.297   1.000 31.00991 ? 465 HOH C O   1 
HETATM 4000 O O   . HOH I 3 .   ? 15.10112  44.83856 -29.32611 1.000 31.77657 ? 466 HOH C O   1 
HETATM 4001 O O   . HOH I 3 .   ? 3.25655   27.54491 -38.46555 1.000 28.64588 ? 467 HOH C O   1 
HETATM 4002 O O   . HOH I 3 .   ? 27.63375  22.84493 -30.85801 1.000 36.95766 ? 468 HOH C O   1 
HETATM 4003 O O   . HOH I 3 .   ? -1.50522  49.22757 -18.49957 1.000 26.33560 ? 469 HOH C O   1 
HETATM 4004 O O   . HOH I 3 .   ? -2.63219  44.81856 -19.09075 1.000 25.30602 ? 470 HOH C O   1 
HETATM 4005 O O   . HOH I 3 .   ? 24.041    32.856   -3.323    1.000 32.57161 ? 471 HOH C O   1 
HETATM 4006 O O   . HOH I 3 .   ? 3.55755   44.09395 -32.27656 1.000 34.89368 ? 472 HOH C O   1 
HETATM 4007 O O   . HOH I 3 .   ? 8.14283   51.00106 -33.68492 1.000 37.29994 ? 473 HOH C O   1 
HETATM 4008 O O   . HOH I 3 .   ? 26.65428  21.69751 -5.57495  1.000 31.60096 ? 474 HOH C O   1 
HETATM 4009 O O   . HOH I 3 .   ? 27.42189  35.43964 -26.68280 1.000 41.73269 ? 475 HOH C O   1 
HETATM 4010 O O   . HOH I 3 .   ? 14.57930  28.21189 -2.08419  1.000 34.11203 ? 476 HOH C O   1 
HETATM 4011 O O   . HOH I 3 .   ? 12.957    33.407   -37.183   1.000 21.46462 ? 477 HOH C O   1 
HETATM 4012 O O   . HOH I 3 .   ? -1.16934  46.03784 -29.82852 1.000 31.85335 ? 478 HOH C O   1 
HETATM 4013 O O   . HOH I 3 .   ? 31.32918  21.27330 -15.37469 1.000 37.17221 ? 479 HOH C O   1 
HETATM 4014 O O   . HOH I 3 .   ? 25.01350  28.02398 -31.15756 1.000 33.51110 ? 480 HOH C O   1 
HETATM 4015 O O   . HOH I 3 .   ? 1.39338   42.37779 -32.19388 1.000 32.04293 ? 481 HOH C O   1 
HETATM 4016 O O   . HOH I 3 .   ? 4.50720   25.68723 -37.06253 1.000 27.94394 ? 482 HOH C O   1 
HETATM 4017 O O   . HOH I 3 .   ? 26.74370  32.59452 -14.45568 1.000 32.10363 ? 483 HOH C O   1 
HETATM 4018 O O   . HOH I 3 .   ? 28.59038  29.49875 -14.77194 1.000 36.20790 ? 484 HOH C O   1 
HETATM 4019 O O   . HOH I 3 .   ? -2.64788  39.02148 -30.85414 1.000 21.27237 ? 485 HOH C O   1 
HETATM 4020 O O   . HOH I 3 .   ? 13.36476  25.82850 -0.76754  1.000 37.48407 ? 486 HOH C O   1 
HETATM 4021 O O   . HOH I 3 .   ? -2.04936  41.56699 -30.11296 1.000 24.70062 ? 487 HOH C O   1 
HETATM 4022 O O   . HOH I 3 .   ? 24.73367  34.74341 -6.07777  1.000 43.40737 ? 488 HOH C O   1 
HETATM 4023 O O   . HOH I 3 .   ? -3.31933  42.87486 -28.10914 1.000 26.27831 ? 489 HOH C O   1 
HETATM 4024 O O   . HOH I 3 .   ? 17.39381  47.53962 -27.47072 1.000 44.64855 ? 490 HOH C O   1 
HETATM 4025 O O   . HOH I 3 .   ? 17.08471  46.81796 -21.62685 1.000 35.18437 ? 491 HOH C O   1 
HETATM 4026 O O   . HOH I 3 .   ? 28.29765  31.64491 -13.05028 1.000 37.33495 ? 492 HOH C O   1 
# 
