data_9N9Y
# 
_entry.id   9N9Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9N9Y         pdb_00009n9y 10.2210/pdb9n9y/pdb 
WWPDB D_1000292831 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'Structure model' 1 1 2025-05-21 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_citation.journal_volume' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9N9Y 
_pdbx_database_status.recvd_initial_deposition_date   2025-02-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dwhittington@tangotx.com 
_pdbx_contact_author.name_first         Douglas 
_pdbx_contact_author.name_last          Whittington 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5946-8543 
# 
_audit_author.name               'Whittington, D.A.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   0000-0002-5946-8543 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Bioorg.Med.Chem.Lett. 
_citation.journal_id_ASTM           BMCLE8 
_citation.journal_id_CSD            1127 
_citation.journal_id_ISSN           1464-3405 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            124 
_citation.language                  ? 
_citation.page_first                130262 
_citation.page_last                 130262 
_citation.title                     'Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.bmcl.2025.130262 
_citation.pdbx_database_id_PubMed   40315934 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Throner, S.'       1  ? 
primary 'Feng, T.'          2  ? 
primary 'Andersen, J.N.'    3  ? 
primary 'Bandi, M.'         4  ? 
primary 'Engel, J.L.'       5  ? 
primary 'Gong, S.'          6  ? 
primary 'Gotur, D.'         7  ? 
primary 'Gu, L.'            8  ? 
primary 'Huang, A.'         9  ? 
primary 'Lazarides, K.'     10 ? 
primary 'Maxwell, J.P.'     11 ? 
primary 'McCarren, P.'      12 ? 
primary 'McMillan, B.J.'    13 ? 
primary 'Pham, T.V.'        14 ? 
primary 'Simoneau, A.'      15 ? 
primary 'Tsai, A.'          16 ? 
primary 'Whittington, D.A.' 17 ? 
primary 'Wilker, E.'        18 ? 
primary 'Zhang, M.'         19 ? 
primary 'Zhang, W.'         20 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'WD repeat-containing protein 48' 64019.430 1  ?         ? 'residues 1-563' 
'C-terminal TEV sequence after cleavage: ENLYFQ' 
2 polymer     man 'Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment,Ubiquitin carboxyl-terminal hydrolase 1' 42954.496 
1  3.4.19.12 'residues 1-84 deleted, residues 223-440 replaced with GSGSGSGSGS, residues 606-738 deleted' ?                ? 
3 non-polymer syn 'ZINC ION' 65.409    1  ?         ? ?                ?                                                
4 non-polymer syn 
;2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-7-({4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl}methyl)-5H-pyrrolo[3,2-d]pyrimidine
;
505.494   1  ?         ?                                                                                            ? ? 
5 water       nat water 18.015    10 ?         ? ?                ?                                                
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'USP1-associated factor 1,WD repeat endosomal protein,p80'                                         
2 'Deubiquitinating enzyme 1,hUBP,Ubiquitin thioesterase 1,Ubiquitin-specific-processing protease 1' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVND
IVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKST
VNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMP
KFNENLYFQ
;
;MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVND
IVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKST
VNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMP
KFNENLYFQ
;
A ? 
2 'polypeptide(L)' no no 
;GNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASF
LLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEGSGSGSGSGSIGFELVEKLFQ
GQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHH
YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISS
GHYTASVKVTDLNSSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL
;
;GNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASF
LLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEGSGSGSGSGSIGFELVEKLFQ
GQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHH
YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISS
GHYTASVKVTDLNSSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL
;
B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'ZINC ION' ZN    
4 
;2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-7-({4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl}methyl)-5H-pyrrolo[3,2-d]pyrimidine
;
A1BWW 
5 water HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   HIS n 
1 5   HIS n 
1 6   ARG n 
1 7   GLN n 
1 8   ASN n 
1 9   THR n 
1 10  ALA n 
1 11  GLY n 
1 12  ARG n 
1 13  ARG n 
1 14  LYS n 
1 15  VAL n 
1 16  GLN n 
1 17  VAL n 
1 18  SER n 
1 19  TYR n 
1 20  VAL n 
1 21  ILE n 
1 22  ARG n 
1 23  ASP n 
1 24  GLU n 
1 25  VAL n 
1 26  GLU n 
1 27  LYS n 
1 28  TYR n 
1 29  ASN n 
1 30  ARG n 
1 31  ASN n 
1 32  GLY n 
1 33  VAL n 
1 34  ASN n 
1 35  ALA n 
1 36  LEU n 
1 37  GLN n 
1 38  LEU n 
1 39  ASP n 
1 40  PRO n 
1 41  ALA n 
1 42  LEU n 
1 43  ASN n 
1 44  ARG n 
1 45  LEU n 
1 46  PHE n 
1 47  THR n 
1 48  ALA n 
1 49  GLY n 
1 50  ARG n 
1 51  ASP n 
1 52  SER n 
1 53  ILE n 
1 54  ILE n 
1 55  ARG n 
1 56  ILE n 
1 57  TRP n 
1 58  SER n 
1 59  VAL n 
1 60  ASN n 
1 61  GLN n 
1 62  HIS n 
1 63  LYS n 
1 64  GLN n 
1 65  ASP n 
1 66  PRO n 
1 67  TYR n 
1 68  ILE n 
1 69  ALA n 
1 70  SER n 
1 71  MET n 
1 72  GLU n 
1 73  HIS n 
1 74  HIS n 
1 75  THR n 
1 76  ASP n 
1 77  TRP n 
1 78  VAL n 
1 79  ASN n 
1 80  ASP n 
1 81  ILE n 
1 82  VAL n 
1 83  LEU n 
1 84  CYS n 
1 85  CYS n 
1 86  ASN n 
1 87  GLY n 
1 88  LYS n 
1 89  THR n 
1 90  LEU n 
1 91  ILE n 
1 92  SER n 
1 93  ALA n 
1 94  SER n 
1 95  SER n 
1 96  ASP n 
1 97  THR n 
1 98  THR n 
1 99  VAL n 
1 100 LYS n 
1 101 VAL n 
1 102 TRP n 
1 103 ASN n 
1 104 ALA n 
1 105 HIS n 
1 106 LYS n 
1 107 GLY n 
1 108 PHE n 
1 109 CYS n 
1 110 MET n 
1 111 SER n 
1 112 THR n 
1 113 LEU n 
1 114 ARG n 
1 115 THR n 
1 116 HIS n 
1 117 LYS n 
1 118 ASP n 
1 119 TYR n 
1 120 VAL n 
1 121 LYS n 
1 122 ALA n 
1 123 LEU n 
1 124 ALA n 
1 125 TYR n 
1 126 ALA n 
1 127 LYS n 
1 128 ASP n 
1 129 LYS n 
1 130 GLU n 
1 131 LEU n 
1 132 VAL n 
1 133 ALA n 
1 134 SER n 
1 135 ALA n 
1 136 GLY n 
1 137 LEU n 
1 138 ASP n 
1 139 ARG n 
1 140 GLN n 
1 141 ILE n 
1 142 PHE n 
1 143 LEU n 
1 144 TRP n 
1 145 ASP n 
1 146 VAL n 
1 147 ASN n 
1 148 THR n 
1 149 LEU n 
1 150 THR n 
1 151 ALA n 
1 152 LEU n 
1 153 THR n 
1 154 ALA n 
1 155 SER n 
1 156 ASN n 
1 157 ASN n 
1 158 THR n 
1 159 VAL n 
1 160 THR n 
1 161 THR n 
1 162 SER n 
1 163 SER n 
1 164 LEU n 
1 165 SER n 
1 166 GLY n 
1 167 ASN n 
1 168 LYS n 
1 169 ASP n 
1 170 SER n 
1 171 ILE n 
1 172 TYR n 
1 173 SER n 
1 174 LEU n 
1 175 ALA n 
1 176 MET n 
1 177 ASN n 
1 178 GLN n 
1 179 LEU n 
1 180 GLY n 
1 181 THR n 
1 182 ILE n 
1 183 ILE n 
1 184 VAL n 
1 185 SER n 
1 186 GLY n 
1 187 SER n 
1 188 THR n 
1 189 GLU n 
1 190 LYS n 
1 191 VAL n 
1 192 LEU n 
1 193 ARG n 
1 194 VAL n 
1 195 TRP n 
1 196 ASP n 
1 197 PRO n 
1 198 ARG n 
1 199 THR n 
1 200 CYS n 
1 201 ALA n 
1 202 LYS n 
1 203 LEU n 
1 204 MET n 
1 205 LYS n 
1 206 LEU n 
1 207 LYS n 
1 208 GLY n 
1 209 HIS n 
1 210 THR n 
1 211 ASP n 
1 212 ASN n 
1 213 VAL n 
1 214 LYS n 
1 215 ALA n 
1 216 LEU n 
1 217 LEU n 
1 218 LEU n 
1 219 ASN n 
1 220 ARG n 
1 221 ASP n 
1 222 GLY n 
1 223 THR n 
1 224 GLN n 
1 225 CYS n 
1 226 LEU n 
1 227 SER n 
1 228 GLY n 
1 229 SER n 
1 230 SER n 
1 231 ASP n 
1 232 GLY n 
1 233 THR n 
1 234 ILE n 
1 235 ARG n 
1 236 LEU n 
1 237 TRP n 
1 238 SER n 
1 239 LEU n 
1 240 GLY n 
1 241 GLN n 
1 242 GLN n 
1 243 ARG n 
1 244 CYS n 
1 245 ILE n 
1 246 ALA n 
1 247 THR n 
1 248 TYR n 
1 249 ARG n 
1 250 VAL n 
1 251 HIS n 
1 252 ASP n 
1 253 GLU n 
1 254 GLY n 
1 255 VAL n 
1 256 TRP n 
1 257 ALA n 
1 258 LEU n 
1 259 GLN n 
1 260 VAL n 
1 261 ASN n 
1 262 ASP n 
1 263 ALA n 
1 264 PHE n 
1 265 THR n 
1 266 HIS n 
1 267 VAL n 
1 268 TYR n 
1 269 SER n 
1 270 GLY n 
1 271 GLY n 
1 272 ARG n 
1 273 ASP n 
1 274 ARG n 
1 275 LYS n 
1 276 ILE n 
1 277 TYR n 
1 278 CYS n 
1 279 THR n 
1 280 ASP n 
1 281 LEU n 
1 282 ARG n 
1 283 ASN n 
1 284 PRO n 
1 285 ASP n 
1 286 ILE n 
1 287 ARG n 
1 288 VAL n 
1 289 LEU n 
1 290 ILE n 
1 291 CYS n 
1 292 GLU n 
1 293 GLU n 
1 294 LYS n 
1 295 ALA n 
1 296 PRO n 
1 297 VAL n 
1 298 LEU n 
1 299 LYS n 
1 300 MET n 
1 301 GLU n 
1 302 LEU n 
1 303 ASP n 
1 304 ARG n 
1 305 SER n 
1 306 ALA n 
1 307 ASP n 
1 308 PRO n 
1 309 PRO n 
1 310 PRO n 
1 311 ALA n 
1 312 ILE n 
1 313 TRP n 
1 314 VAL n 
1 315 ALA n 
1 316 THR n 
1 317 THR n 
1 318 LYS n 
1 319 SER n 
1 320 THR n 
1 321 VAL n 
1 322 ASN n 
1 323 LYS n 
1 324 TRP n 
1 325 THR n 
1 326 LEU n 
1 327 LYS n 
1 328 GLY n 
1 329 ILE n 
1 330 HIS n 
1 331 ASN n 
1 332 PHE n 
1 333 ARG n 
1 334 ALA n 
1 335 SER n 
1 336 GLY n 
1 337 ASP n 
1 338 TYR n 
1 339 ASP n 
1 340 ASN n 
1 341 ASP n 
1 342 CYS n 
1 343 THR n 
1 344 ASN n 
1 345 PRO n 
1 346 ILE n 
1 347 THR n 
1 348 PRO n 
1 349 LEU n 
1 350 CYS n 
1 351 THR n 
1 352 GLN n 
1 353 PRO n 
1 354 ASP n 
1 355 GLN n 
1 356 VAL n 
1 357 ILE n 
1 358 LYS n 
1 359 GLY n 
1 360 GLY n 
1 361 ALA n 
1 362 SER n 
1 363 ILE n 
1 364 ILE n 
1 365 GLN n 
1 366 CYS n 
1 367 HIS n 
1 368 ILE n 
1 369 LEU n 
1 370 ASN n 
1 371 ASP n 
1 372 LYS n 
1 373 ARG n 
1 374 HIS n 
1 375 ILE n 
1 376 LEU n 
1 377 THR n 
1 378 LYS n 
1 379 ASP n 
1 380 THR n 
1 381 ASN n 
1 382 ASN n 
1 383 ASN n 
1 384 VAL n 
1 385 ALA n 
1 386 TYR n 
1 387 TRP n 
1 388 ASP n 
1 389 VAL n 
1 390 LEU n 
1 391 LYS n 
1 392 ALA n 
1 393 CYS n 
1 394 LYS n 
1 395 VAL n 
1 396 GLU n 
1 397 ASP n 
1 398 LEU n 
1 399 GLY n 
1 400 LYS n 
1 401 VAL n 
1 402 ASP n 
1 403 PHE n 
1 404 GLU n 
1 405 ASP n 
1 406 GLU n 
1 407 ILE n 
1 408 LYS n 
1 409 LYS n 
1 410 ARG n 
1 411 PHE n 
1 412 LYS n 
1 413 MET n 
1 414 VAL n 
1 415 TYR n 
1 416 VAL n 
1 417 PRO n 
1 418 ASN n 
1 419 TRP n 
1 420 PHE n 
1 421 SER n 
1 422 VAL n 
1 423 ASP n 
1 424 LEU n 
1 425 LYS n 
1 426 THR n 
1 427 GLY n 
1 428 MET n 
1 429 LEU n 
1 430 THR n 
1 431 ILE n 
1 432 THR n 
1 433 LEU n 
1 434 ASP n 
1 435 GLU n 
1 436 SER n 
1 437 ASP n 
1 438 CYS n 
1 439 PHE n 
1 440 ALA n 
1 441 ALA n 
1 442 TRP n 
1 443 VAL n 
1 444 SER n 
1 445 ALA n 
1 446 LYS n 
1 447 ASP n 
1 448 ALA n 
1 449 GLY n 
1 450 PHE n 
1 451 SER n 
1 452 SER n 
1 453 PRO n 
1 454 ASP n 
1 455 GLY n 
1 456 SER n 
1 457 ASP n 
1 458 PRO n 
1 459 LYS n 
1 460 LEU n 
1 461 ASN n 
1 462 LEU n 
1 463 GLY n 
1 464 GLY n 
1 465 LEU n 
1 466 LEU n 
1 467 LEU n 
1 468 GLN n 
1 469 ALA n 
1 470 LEU n 
1 471 LEU n 
1 472 GLU n 
1 473 TYR n 
1 474 TRP n 
1 475 PRO n 
1 476 ARG n 
1 477 THR n 
1 478 HIS n 
1 479 VAL n 
1 480 ASN n 
1 481 PRO n 
1 482 MET n 
1 483 ASP n 
1 484 GLU n 
1 485 GLU n 
1 486 GLU n 
1 487 ASN n 
1 488 GLU n 
1 489 VAL n 
1 490 ASN n 
1 491 HIS n 
1 492 VAL n 
1 493 ASN n 
1 494 GLY n 
1 495 GLU n 
1 496 GLN n 
1 497 GLU n 
1 498 ASN n 
1 499 ARG n 
1 500 VAL n 
1 501 GLN n 
1 502 LYS n 
1 503 GLY n 
1 504 ASN n 
1 505 GLY n 
1 506 TYR n 
1 507 PHE n 
1 508 GLN n 
1 509 VAL n 
1 510 PRO n 
1 511 PRO n 
1 512 HIS n 
1 513 THR n 
1 514 PRO n 
1 515 VAL n 
1 516 ILE n 
1 517 PHE n 
1 518 GLY n 
1 519 GLU n 
1 520 ALA n 
1 521 GLY n 
1 522 GLY n 
1 523 ARG n 
1 524 THR n 
1 525 LEU n 
1 526 PHE n 
1 527 ARG n 
1 528 LEU n 
1 529 LEU n 
1 530 CYS n 
1 531 ARG n 
1 532 ASP n 
1 533 SER n 
1 534 GLY n 
1 535 GLY n 
1 536 GLU n 
1 537 THR n 
1 538 GLU n 
1 539 SER n 
1 540 MET n 
1 541 LEU n 
1 542 LEU n 
1 543 ASN n 
1 544 GLU n 
1 545 THR n 
1 546 VAL n 
1 547 PRO n 
1 548 GLN n 
1 549 TRP n 
1 550 VAL n 
1 551 ILE n 
1 552 ASP n 
1 553 ILE n 
1 554 THR n 
1 555 VAL n 
1 556 ASP n 
1 557 LYS n 
1 558 ASN n 
1 559 MET n 
1 560 PRO n 
1 561 LYS n 
1 562 PHE n 
1 563 ASN n 
1 564 GLU n 
1 565 ASN n 
1 566 LEU n 
1 567 TYR n 
1 568 PHE n 
1 569 GLN n 
2 1   GLY n 
2 2   ASN n 
2 3   LEU n 
2 4   GLY n 
2 5   ASN n 
2 6   THR n 
2 7   CYS n 
2 8   TYR n 
2 9   LEU n 
2 10  ASN n 
2 11  SER n 
2 12  ILE n 
2 13  LEU n 
2 14  GLN n 
2 15  VAL n 
2 16  LEU n 
2 17  TYR n 
2 18  PHE n 
2 19  CYS n 
2 20  PRO n 
2 21  GLY n 
2 22  PHE n 
2 23  LYS n 
2 24  SER n 
2 25  GLY n 
2 26  VAL n 
2 27  LYS n 
2 28  HIS n 
2 29  LEU n 
2 30  PHE n 
2 31  ASN n 
2 32  ILE n 
2 33  ILE n 
2 34  SER n 
2 35  ARG n 
2 36  LYS n 
2 37  LYS n 
2 38  GLU n 
2 39  ALA n 
2 40  LEU n 
2 41  LYS n 
2 42  ASP n 
2 43  GLU n 
2 44  ALA n 
2 45  ASN n 
2 46  GLN n 
2 47  LYS n 
2 48  ASP n 
2 49  LYS n 
2 50  GLY n 
2 51  ASN n 
2 52  CYS n 
2 53  LYS n 
2 54  GLU n 
2 55  ASP n 
2 56  SER n 
2 57  LEU n 
2 58  ALA n 
2 59  SER n 
2 60  TYR n 
2 61  GLU n 
2 62  LEU n 
2 63  ILE n 
2 64  CYS n 
2 65  SER n 
2 66  LEU n 
2 67  GLN n 
2 68  SER n 
2 69  LEU n 
2 70  ILE n 
2 71  ILE n 
2 72  SER n 
2 73  VAL n 
2 74  GLU n 
2 75  GLN n 
2 76  LEU n 
2 77  GLN n 
2 78  ALA n 
2 79  SER n 
2 80  PHE n 
2 81  LEU n 
2 82  LEU n 
2 83  ASN n 
2 84  PRO n 
2 85  GLU n 
2 86  LYS n 
2 87  TYR n 
2 88  THR n 
2 89  ASP n 
2 90  GLU n 
2 91  LEU n 
2 92  ALA n 
2 93  THR n 
2 94  GLN n 
2 95  PRO n 
2 96  ARG n 
2 97  ARG n 
2 98  LEU n 
2 99  LEU n 
2 100 ASN n 
2 101 THR n 
2 102 LEU n 
2 103 ARG n 
2 104 GLU n 
2 105 LEU n 
2 106 ASN n 
2 107 PRO n 
2 108 MET n 
2 109 TYR n 
2 110 GLU n 
2 111 GLY n 
2 112 TYR n 
2 113 LEU n 
2 114 GLN n 
2 115 HIS n 
2 116 ASP n 
2 117 ALA n 
2 118 GLN n 
2 119 GLU n 
2 120 VAL n 
2 121 LEU n 
2 122 GLN n 
2 123 CYS n 
2 124 ILE n 
2 125 LEU n 
2 126 GLY n 
2 127 ASN n 
2 128 ILE n 
2 129 GLN n 
2 130 GLU n 
2 131 THR n 
2 132 CYS n 
2 133 GLN n 
2 134 LEU n 
2 135 LEU n 
2 136 LYS n 
2 137 LYS n 
2 138 GLU n 
2 139 GLU n 
2 140 GLY n 
2 141 SER n 
2 142 GLY n 
2 143 SER n 
2 144 GLY n 
2 145 SER n 
2 146 GLY n 
2 147 SER n 
2 148 GLY n 
2 149 SER n 
2 150 ILE n 
2 151 GLY n 
2 152 PHE n 
2 153 GLU n 
2 154 LEU n 
2 155 VAL n 
2 156 GLU n 
2 157 LYS n 
2 158 LEU n 
2 159 PHE n 
2 160 GLN n 
2 161 GLY n 
2 162 GLN n 
2 163 LEU n 
2 164 VAL n 
2 165 LEU n 
2 166 ARG n 
2 167 THR n 
2 168 ARG n 
2 169 CYS n 
2 170 LEU n 
2 171 GLU n 
2 172 CYS n 
2 173 GLU n 
2 174 SER n 
2 175 LEU n 
2 176 THR n 
2 177 GLU n 
2 178 ARG n 
2 179 ARG n 
2 180 GLU n 
2 181 ASP n 
2 182 PHE n 
2 183 GLN n 
2 184 ASP n 
2 185 ILE n 
2 186 SER n 
2 187 VAL n 
2 188 PRO n 
2 189 VAL n 
2 190 GLN n 
2 191 GLU n 
2 192 ASP n 
2 193 GLU n 
2 194 LEU n 
2 195 SER n 
2 196 LYS n 
2 197 VAL n 
2 198 GLU n 
2 199 GLU n 
2 200 SER n 
2 201 SER n 
2 202 GLU n 
2 203 ILE n 
2 204 SER n 
2 205 PRO n 
2 206 GLU n 
2 207 PRO n 
2 208 LYS n 
2 209 THR n 
2 210 GLU n 
2 211 MET n 
2 212 LYS n 
2 213 THR n 
2 214 LEU n 
2 215 ARG n 
2 216 TRP n 
2 217 ALA n 
2 218 ILE n 
2 219 SER n 
2 220 GLN n 
2 221 PHE n 
2 222 ALA n 
2 223 SER n 
2 224 VAL n 
2 225 GLU n 
2 226 ARG n 
2 227 ILE n 
2 228 VAL n 
2 229 GLY n 
2 230 GLU n 
2 231 ASP n 
2 232 LYS n 
2 233 TYR n 
2 234 PHE n 
2 235 CYS n 
2 236 GLU n 
2 237 ASN n 
2 238 CYS n 
2 239 HIS n 
2 240 HIS n 
2 241 TYR n 
2 242 THR n 
2 243 GLU n 
2 244 ALA n 
2 245 GLU n 
2 246 ARG n 
2 247 SER n 
2 248 LEU n 
2 249 LEU n 
2 250 PHE n 
2 251 ASP n 
2 252 LYS n 
2 253 MET n 
2 254 PRO n 
2 255 GLU n 
2 256 VAL n 
2 257 ILE n 
2 258 THR n 
2 259 ILE n 
2 260 HIS n 
2 261 LEU n 
2 262 LYS n 
2 263 CYS n 
2 264 PHE n 
2 265 ALA n 
2 266 ALA n 
2 267 SER n 
2 268 GLY n 
2 269 LEU n 
2 270 GLU n 
2 271 PHE n 
2 272 ASP n 
2 273 CYS n 
2 274 TYR n 
2 275 GLY n 
2 276 GLY n 
2 277 GLY n 
2 278 LEU n 
2 279 SER n 
2 280 LYS n 
2 281 ILE n 
2 282 ASN n 
2 283 THR n 
2 284 PRO n 
2 285 LEU n 
2 286 LEU n 
2 287 THR n 
2 288 PRO n 
2 289 LEU n 
2 290 LYS n 
2 291 LEU n 
2 292 SER n 
2 293 LEU n 
2 294 GLU n 
2 295 GLU n 
2 296 TRP n 
2 297 SER n 
2 298 THR n 
2 299 LYS n 
2 300 PRO n 
2 301 THR n 
2 302 ASN n 
2 303 ASP n 
2 304 SER n 
2 305 TYR n 
2 306 GLY n 
2 307 LEU n 
2 308 PHE n 
2 309 ALA n 
2 310 VAL n 
2 311 VAL n 
2 312 MET n 
2 313 HIS n 
2 314 SER n 
2 315 GLY n 
2 316 ILE n 
2 317 THR n 
2 318 ILE n 
2 319 SER n 
2 320 SER n 
2 321 GLY n 
2 322 HIS n 
2 323 TYR n 
2 324 THR n 
2 325 ALA n 
2 326 SER n 
2 327 VAL n 
2 328 LYS n 
2 329 VAL n 
2 330 THR n 
2 331 ASP n 
2 332 LEU n 
2 333 ASN n 
2 334 SER n 
2 335 SER n 
2 336 LEU n 
2 337 LYS n 
2 338 GLU n 
2 339 TYR n 
2 340 GLU n 
2 341 GLY n 
2 342 LYS n 
2 343 TRP n 
2 344 LEU n 
2 345 LEU n 
2 346 PHE n 
2 347 ASP n 
2 348 ASP n 
2 349 SER n 
2 350 GLU n 
2 351 VAL n 
2 352 LYS n 
2 353 VAL n 
2 354 THR n 
2 355 GLU n 
2 356 GLU n 
2 357 LYS n 
2 358 ASP n 
2 359 PHE n 
2 360 LEU n 
2 361 ASN n 
2 362 SER n 
2 363 LEU n 
2 364 SER n 
2 365 PRO n 
2 366 SER n 
2 367 THR n 
2 368 SER n 
2 369 PRO n 
2 370 THR n 
2 371 SER n 
2 372 THR n 
2 373 PRO n 
2 374 TYR n 
2 375 LEU n 
2 376 LEU n 
2 377 PHE n 
2 378 TYR n 
2 379 LYS n 
2 380 LYS n 
2 381 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   569 human ? 'WDR48, KIAA1449, UAF1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   149 human ? USP1                    ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 2 sample 'Biological sequence' 150 334 human ? USP1                    ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 3 sample 'Biological sequence' 335 381 human ? USP1                    ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1BWW non-polymer         . 
;2-(4-cyclopropyl-6-methoxypyrimidin-5-yl)-7-({4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl}methyl)-5H-pyrrolo[3,2-d]pyrimidine
;
? 'C26 H22 F3 N7 O' 505.494 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'      89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'  175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'     132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'      133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'    121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'    146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'      147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'      75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'  156.162 
HOH   non-polymer         . WATER ? 'H2 O'            18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'     131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'     131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'  147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'   149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'     165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'      115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'      105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'      119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'   204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'     181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'     117.146 
ZN    non-polymer         . 'ZINC ION' ? 'Zn 2'            65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   HIS 4   4   ?   ?   ?   A . n 
A 1 5   HIS 5   5   ?   ?   ?   A . n 
A 1 6   ARG 6   6   ?   ?   ?   A . n 
A 1 7   GLN 7   7   ?   ?   ?   A . n 
A 1 8   ASN 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  ALA 10  10  ?   ?   ?   A . n 
A 1 11  GLY 11  11  ?   ?   ?   A . n 
A 1 12  ARG 12  12  ?   ?   ?   A . n 
A 1 13  ARG 13  13  13  ARG ARG A . n 
A 1 14  LYS 14  14  14  LYS LYS A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  GLN 16  16  16  GLN GLN A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  SER 18  18  18  SER SER A . n 
A 1 19  TYR 19  19  19  TYR TYR A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  GLU 24  24  24  GLU GLU A . n 
A 1 25  VAL 25  25  25  VAL VAL A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  LYS 27  27  27  LYS LYS A . n 
A 1 28  TYR 28  28  28  TYR TYR A . n 
A 1 29  ASN 29  29  29  ASN ASN A . n 
A 1 30  ARG 30  30  30  ARG ARG A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  VAL 33  33  33  VAL VAL A . n 
A 1 34  ASN 34  34  34  ASN ASN A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ASP 39  39  39  ASP ASP A . n 
A 1 40  PRO 40  40  40  PRO PRO A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  ASN 43  43  43  ASN ASN A . n 
A 1 44  ARG 44  44  44  ARG ARG A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  PHE 46  46  46  PHE PHE A . n 
A 1 47  THR 47  47  47  THR THR A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  ARG 50  50  50  ARG ARG A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  ARG 55  55  55  ARG ARG A . n 
A 1 56  ILE 56  56  56  ILE ILE A . n 
A 1 57  TRP 57  57  57  TRP TRP A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  ASN 60  60  60  ASN ASN A . n 
A 1 61  GLN 61  61  61  GLN GLN A . n 
A 1 62  HIS 62  62  62  HIS HIS A . n 
A 1 63  LYS 63  63  63  LYS LYS A . n 
A 1 64  GLN 64  64  64  GLN GLN A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  PRO 66  66  66  PRO PRO A . n 
A 1 67  TYR 67  67  67  TYR TYR A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  SER 70  70  70  SER SER A . n 
A 1 71  MET 71  71  71  MET MET A . n 
A 1 72  GLU 72  72  72  GLU GLU A . n 
A 1 73  HIS 73  73  73  HIS HIS A . n 
A 1 74  HIS 74  74  74  HIS HIS A . n 
A 1 75  THR 75  75  75  THR THR A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  TRP 77  77  77  TRP TRP A . n 
A 1 78  VAL 78  78  78  VAL VAL A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  ASP 80  80  80  ASP ASP A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  VAL 82  82  82  VAL VAL A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  CYS 84  84  84  CYS CYS A . n 
A 1 85  CYS 85  85  85  CYS CYS A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  LEU 90  90  90  LEU LEU A . n 
A 1 91  ILE 91  91  91  ILE ILE A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  SER 95  95  95  SER SER A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  THR 97  97  97  THR THR A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 VAL 101 101 101 VAL VAL A . n 
A 1 102 TRP 102 102 102 TRP TRP A . n 
A 1 103 ASN 103 103 103 ASN ASN A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 HIS 105 105 105 HIS HIS A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 CYS 109 109 109 CYS CYS A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 ARG 114 114 114 ARG ARG A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 HIS 116 116 116 HIS HIS A . n 
A 1 117 LYS 117 117 117 LYS LYS A . n 
A 1 118 ASP 118 118 118 ASP ASP A . n 
A 1 119 TYR 119 119 119 TYR TYR A . n 
A 1 120 VAL 120 120 120 VAL VAL A . n 
A 1 121 LYS 121 121 121 LYS LYS A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 ASP 128 128 128 ASP ASP A . n 
A 1 129 LYS 129 129 129 LYS LYS A . n 
A 1 130 GLU 130 130 130 GLU GLU A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 ALA 135 135 135 ALA ALA A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 GLN 140 140 140 GLN GLN A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 TRP 144 144 144 TRP TRP A . n 
A 1 145 ASP 145 145 145 ASP ASP A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 ASN 147 147 147 ASN ASN A . n 
A 1 148 THR 148 148 148 THR THR A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 THR 150 150 150 THR THR A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 THR 153 153 153 THR THR A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 ASN 156 156 156 ASN ASN A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 THR 161 161 161 THR THR A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 SER 163 163 163 SER SER A . n 
A 1 164 LEU 164 164 164 LEU LEU A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 GLY 166 166 166 GLY GLY A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 LYS 168 168 168 LYS LYS A . n 
A 1 169 ASP 169 169 169 ASP ASP A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 ILE 171 171 171 ILE ILE A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 SER 173 173 173 SER SER A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 ALA 175 175 175 ALA ALA A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 ASN 177 177 177 ASN ASN A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 THR 181 181 181 THR THR A . n 
A 1 182 ILE 182 182 182 ILE ILE A . n 
A 1 183 ILE 183 183 183 ILE ILE A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 GLY 186 186 186 GLY GLY A . n 
A 1 187 SER 187 187 187 SER SER A . n 
A 1 188 THR 188 188 188 THR THR A . n 
A 1 189 GLU 189 189 189 GLU GLU A . n 
A 1 190 LYS 190 190 190 LYS LYS A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 TRP 195 195 195 TRP TRP A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 PRO 197 197 197 PRO PRO A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 CYS 200 200 200 CYS CYS A . n 
A 1 201 ALA 201 201 201 ALA ALA A . n 
A 1 202 LYS 202 202 202 LYS LYS A . n 
A 1 203 LEU 203 203 203 LEU LEU A . n 
A 1 204 MET 204 204 204 MET MET A . n 
A 1 205 LYS 205 205 205 LYS LYS A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 HIS 209 209 209 HIS HIS A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 ASP 211 211 211 ASP ASP A . n 
A 1 212 ASN 212 212 212 ASN ASN A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 LYS 214 214 214 LYS LYS A . n 
A 1 215 ALA 215 215 215 ALA ALA A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 ASN 219 219 219 ASN ASN A . n 
A 1 220 ARG 220 220 220 ARG ARG A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 GLY 222 222 222 GLY GLY A . n 
A 1 223 THR 223 223 223 THR THR A . n 
A 1 224 GLN 224 224 224 GLN GLN A . n 
A 1 225 CYS 225 225 225 CYS CYS A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 SER 227 227 227 SER SER A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 SER 229 229 229 SER SER A . n 
A 1 230 SER 230 230 230 SER SER A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 GLY 232 232 232 GLY GLY A . n 
A 1 233 THR 233 233 233 THR THR A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 ARG 235 235 235 ARG ARG A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 TRP 237 237 237 TRP TRP A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 GLN 241 241 241 GLN GLN A . n 
A 1 242 GLN 242 242 242 GLN GLN A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 CYS 244 244 244 CYS CYS A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 TYR 248 248 248 TYR TYR A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 VAL 250 250 250 VAL VAL A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 ASP 252 252 252 ASP ASP A . n 
A 1 253 GLU 253 253 253 GLU GLU A . n 
A 1 254 GLY 254 254 254 GLY GLY A . n 
A 1 255 VAL 255 255 255 VAL VAL A . n 
A 1 256 TRP 256 256 256 TRP TRP A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 GLN 259 259 259 GLN GLN A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 ASN 261 261 261 ASN ASN A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 ALA 263 263 263 ALA ALA A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 THR 265 265 265 THR THR A . n 
A 1 266 HIS 266 266 266 HIS HIS A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 TYR 268 268 268 TYR TYR A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 GLY 270 270 270 GLY GLY A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 ARG 272 272 272 ARG ARG A . n 
A 1 273 ASP 273 273 273 ASP ASP A . n 
A 1 274 ARG 274 274 274 ARG ARG A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 CYS 278 278 278 CYS CYS A . n 
A 1 279 THR 279 279 279 THR THR A . n 
A 1 280 ASP 280 280 280 ASP ASP A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 ARG 282 282 282 ARG ARG A . n 
A 1 283 ASN 283 283 283 ASN ASN A . n 
A 1 284 PRO 284 284 284 PRO PRO A . n 
A 1 285 ASP 285 285 285 ASP ASP A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 LEU 289 289 289 LEU LEU A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 CYS 291 291 291 CYS CYS A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 GLU 293 293 293 GLU GLU A . n 
A 1 294 LYS 294 294 294 LYS LYS A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 LYS 299 299 299 LYS LYS A . n 
A 1 300 MET 300 300 300 MET MET A . n 
A 1 301 GLU 301 301 301 GLU GLU A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 ARG 304 304 304 ARG ARG A . n 
A 1 305 SER 305 305 305 SER SER A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 PRO 308 308 308 PRO PRO A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 PRO 310 310 310 PRO PRO A . n 
A 1 311 ALA 311 311 311 ALA ALA A . n 
A 1 312 ILE 312 312 312 ILE ILE A . n 
A 1 313 TRP 313 313 313 TRP TRP A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 THR 317 317 317 THR THR A . n 
A 1 318 LYS 318 318 318 LYS LYS A . n 
A 1 319 SER 319 319 319 SER SER A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 VAL 321 321 321 VAL VAL A . n 
A 1 322 ASN 322 322 322 ASN ASN A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 TRP 324 324 324 TRP TRP A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 LYS 327 327 327 LYS LYS A . n 
A 1 328 GLY 328 328 328 GLY GLY A . n 
A 1 329 ILE 329 329 329 ILE ILE A . n 
A 1 330 HIS 330 330 ?   ?   ?   A . n 
A 1 331 ASN 331 331 ?   ?   ?   A . n 
A 1 332 PHE 332 332 ?   ?   ?   A . n 
A 1 333 ARG 333 333 ?   ?   ?   A . n 
A 1 334 ALA 334 334 ?   ?   ?   A . n 
A 1 335 SER 335 335 ?   ?   ?   A . n 
A 1 336 GLY 336 336 ?   ?   ?   A . n 
A 1 337 ASP 337 337 ?   ?   ?   A . n 
A 1 338 TYR 338 338 ?   ?   ?   A . n 
A 1 339 ASP 339 339 ?   ?   ?   A . n 
A 1 340 ASN 340 340 ?   ?   ?   A . n 
A 1 341 ASP 341 341 ?   ?   ?   A . n 
A 1 342 CYS 342 342 ?   ?   ?   A . n 
A 1 343 THR 343 343 343 THR THR A . n 
A 1 344 ASN 344 344 344 ASN ASN A . n 
A 1 345 PRO 345 345 345 PRO PRO A . n 
A 1 346 ILE 346 346 346 ILE ILE A . n 
A 1 347 THR 347 347 347 THR THR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 CYS 350 350 350 CYS CYS A . n 
A 1 351 THR 351 351 351 THR THR A . n 
A 1 352 GLN 352 352 352 GLN GLN A . n 
A 1 353 PRO 353 353 353 PRO PRO A . n 
A 1 354 ASP 354 354 354 ASP ASP A . n 
A 1 355 GLN 355 355 355 GLN GLN A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 LYS 358 358 358 LYS LYS A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 GLY 360 360 360 GLY GLY A . n 
A 1 361 ALA 361 361 361 ALA ALA A . n 
A 1 362 SER 362 362 362 SER SER A . n 
A 1 363 ILE 363 363 363 ILE ILE A . n 
A 1 364 ILE 364 364 364 ILE ILE A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 CYS 366 366 366 CYS CYS A . n 
A 1 367 HIS 367 367 367 HIS HIS A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 ASN 370 370 370 ASN ASN A . n 
A 1 371 ASP 371 371 371 ASP ASP A . n 
A 1 372 LYS 372 372 372 LYS LYS A . n 
A 1 373 ARG 373 373 373 ARG ARG A . n 
A 1 374 HIS 374 374 374 HIS HIS A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 LEU 376 376 376 LEU LEU A . n 
A 1 377 THR 377 377 377 THR THR A . n 
A 1 378 LYS 378 378 378 LYS LYS A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 THR 380 380 380 THR THR A . n 
A 1 381 ASN 381 381 381 ASN ASN A . n 
A 1 382 ASN 382 382 382 ASN ASN A . n 
A 1 383 ASN 383 383 383 ASN ASN A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 ALA 385 385 385 ALA ALA A . n 
A 1 386 TYR 386 386 386 TYR TYR A . n 
A 1 387 TRP 387 387 387 TRP TRP A . n 
A 1 388 ASP 388 388 388 ASP ASP A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 LYS 391 391 391 LYS LYS A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 CYS 393 393 393 CYS CYS A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 GLU 396 396 396 GLU GLU A . n 
A 1 397 ASP 397 397 397 ASP ASP A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 GLY 399 399 399 GLY GLY A . n 
A 1 400 LYS 400 400 400 LYS LYS A . n 
A 1 401 VAL 401 401 401 VAL VAL A . n 
A 1 402 ASP 402 402 402 ASP ASP A . n 
A 1 403 PHE 403 403 403 PHE PHE A . n 
A 1 404 GLU 404 404 404 GLU GLU A . n 
A 1 405 ASP 405 405 405 ASP ASP A . n 
A 1 406 GLU 406 406 406 GLU GLU A . n 
A 1 407 ILE 407 407 407 ILE ILE A . n 
A 1 408 LYS 408 408 408 LYS LYS A . n 
A 1 409 LYS 409 409 409 LYS LYS A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 PHE 411 411 411 PHE PHE A . n 
A 1 412 LYS 412 412 412 LYS LYS A . n 
A 1 413 MET 413 413 413 MET MET A . n 
A 1 414 VAL 414 414 414 VAL VAL A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 VAL 416 416 416 VAL VAL A . n 
A 1 417 PRO 417 417 417 PRO PRO A . n 
A 1 418 ASN 418 418 418 ASN ASN A . n 
A 1 419 TRP 419 419 419 TRP TRP A . n 
A 1 420 PHE 420 420 420 PHE PHE A . n 
A 1 421 SER 421 421 421 SER SER A . n 
A 1 422 VAL 422 422 422 VAL VAL A . n 
A 1 423 ASP 423 423 423 ASP ASP A . n 
A 1 424 LEU 424 424 424 LEU LEU A . n 
A 1 425 LYS 425 425 425 LYS LYS A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 GLY 427 427 427 GLY GLY A . n 
A 1 428 MET 428 428 428 MET MET A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 THR 430 430 430 THR THR A . n 
A 1 431 ILE 431 431 431 ILE ILE A . n 
A 1 432 THR 432 432 432 THR THR A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ASP 434 434 434 ASP ASP A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 ASP 437 437 437 ASP ASP A . n 
A 1 438 CYS 438 438 438 CYS CYS A . n 
A 1 439 PHE 439 439 439 PHE PHE A . n 
A 1 440 ALA 440 440 440 ALA ALA A . n 
A 1 441 ALA 441 441 441 ALA ALA A . n 
A 1 442 TRP 442 442 442 TRP TRP A . n 
A 1 443 VAL 443 443 443 VAL VAL A . n 
A 1 444 SER 444 444 444 SER SER A . n 
A 1 445 ALA 445 445 445 ALA ALA A . n 
A 1 446 LYS 446 446 446 LYS LYS A . n 
A 1 447 ASP 447 447 447 ASP ASP A . n 
A 1 448 ALA 448 448 448 ALA ALA A . n 
A 1 449 GLY 449 449 449 GLY GLY A . n 
A 1 450 PHE 450 450 450 PHE PHE A . n 
A 1 451 SER 451 451 451 SER SER A . n 
A 1 452 SER 452 452 452 SER SER A . n 
A 1 453 PRO 453 453 453 PRO PRO A . n 
A 1 454 ASP 454 454 454 ASP ASP A . n 
A 1 455 GLY 455 455 455 GLY GLY A . n 
A 1 456 SER 456 456 456 SER SER A . n 
A 1 457 ASP 457 457 457 ASP ASP A . n 
A 1 458 PRO 458 458 458 PRO PRO A . n 
A 1 459 LYS 459 459 459 LYS LYS A . n 
A 1 460 LEU 460 460 460 LEU LEU A . n 
A 1 461 ASN 461 461 461 ASN ASN A . n 
A 1 462 LEU 462 462 462 LEU LEU A . n 
A 1 463 GLY 463 463 463 GLY GLY A . n 
A 1 464 GLY 464 464 464 GLY GLY A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 LEU 466 466 466 LEU LEU A . n 
A 1 467 LEU 467 467 467 LEU LEU A . n 
A 1 468 GLN 468 468 468 GLN GLN A . n 
A 1 469 ALA 469 469 469 ALA ALA A . n 
A 1 470 LEU 470 470 470 LEU LEU A . n 
A 1 471 LEU 471 471 471 LEU LEU A . n 
A 1 472 GLU 472 472 472 GLU GLU A . n 
A 1 473 TYR 473 473 473 TYR TYR A . n 
A 1 474 TRP 474 474 474 TRP TRP A . n 
A 1 475 PRO 475 475 475 PRO PRO A . n 
A 1 476 ARG 476 476 476 ARG ARG A . n 
A 1 477 THR 477 477 477 THR THR A . n 
A 1 478 HIS 478 478 478 HIS HIS A . n 
A 1 479 VAL 479 479 479 VAL VAL A . n 
A 1 480 ASN 480 480 480 ASN ASN A . n 
A 1 481 PRO 481 481 ?   ?   ?   A . n 
A 1 482 MET 482 482 ?   ?   ?   A . n 
A 1 483 ASP 483 483 ?   ?   ?   A . n 
A 1 484 GLU 484 484 ?   ?   ?   A . n 
A 1 485 GLU 485 485 ?   ?   ?   A . n 
A 1 486 GLU 486 486 ?   ?   ?   A . n 
A 1 487 ASN 487 487 ?   ?   ?   A . n 
A 1 488 GLU 488 488 ?   ?   ?   A . n 
A 1 489 VAL 489 489 ?   ?   ?   A . n 
A 1 490 ASN 490 490 ?   ?   ?   A . n 
A 1 491 HIS 491 491 ?   ?   ?   A . n 
A 1 492 VAL 492 492 ?   ?   ?   A . n 
A 1 493 ASN 493 493 ?   ?   ?   A . n 
A 1 494 GLY 494 494 ?   ?   ?   A . n 
A 1 495 GLU 495 495 ?   ?   ?   A . n 
A 1 496 GLN 496 496 ?   ?   ?   A . n 
A 1 497 GLU 497 497 ?   ?   ?   A . n 
A 1 498 ASN 498 498 ?   ?   ?   A . n 
A 1 499 ARG 499 499 ?   ?   ?   A . n 
A 1 500 VAL 500 500 500 VAL VAL A . n 
A 1 501 GLN 501 501 501 GLN GLN A . n 
A 1 502 LYS 502 502 502 LYS LYS A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 ASN 504 504 504 ASN ASN A . n 
A 1 505 GLY 505 505 505 GLY GLY A . n 
A 1 506 TYR 506 506 506 TYR TYR A . n 
A 1 507 PHE 507 507 507 PHE PHE A . n 
A 1 508 GLN 508 508 508 GLN GLN A . n 
A 1 509 VAL 509 509 509 VAL VAL A . n 
A 1 510 PRO 510 510 510 PRO PRO A . n 
A 1 511 PRO 511 511 511 PRO PRO A . n 
A 1 512 HIS 512 512 512 HIS HIS A . n 
A 1 513 THR 513 513 513 THR THR A . n 
A 1 514 PRO 514 514 514 PRO PRO A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 ILE 516 516 516 ILE ILE A . n 
A 1 517 PHE 517 517 517 PHE PHE A . n 
A 1 518 GLY 518 518 518 GLY GLY A . n 
A 1 519 GLU 519 519 519 GLU GLU A . n 
A 1 520 ALA 520 520 520 ALA ALA A . n 
A 1 521 GLY 521 521 521 GLY GLY A . n 
A 1 522 GLY 522 522 522 GLY GLY A . n 
A 1 523 ARG 523 523 523 ARG ARG A . n 
A 1 524 THR 524 524 524 THR THR A . n 
A 1 525 LEU 525 525 525 LEU LEU A . n 
A 1 526 PHE 526 526 526 PHE PHE A . n 
A 1 527 ARG 527 527 527 ARG ARG A . n 
A 1 528 LEU 528 528 528 LEU LEU A . n 
A 1 529 LEU 529 529 529 LEU LEU A . n 
A 1 530 CYS 530 530 530 CYS CYS A . n 
A 1 531 ARG 531 531 531 ARG ARG A . n 
A 1 532 ASP 532 532 532 ASP ASP A . n 
A 1 533 SER 533 533 533 SER SER A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 GLU 536 536 536 GLU GLU A . n 
A 1 537 THR 537 537 537 THR THR A . n 
A 1 538 GLU 538 538 538 GLU GLU A . n 
A 1 539 SER 539 539 539 SER SER A . n 
A 1 540 MET 540 540 540 MET MET A . n 
A 1 541 LEU 541 541 541 LEU LEU A . n 
A 1 542 LEU 542 542 542 LEU LEU A . n 
A 1 543 ASN 543 543 543 ASN ASN A . n 
A 1 544 GLU 544 544 544 GLU GLU A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 PRO 547 547 547 PRO PRO A . n 
A 1 548 GLN 548 548 548 GLN GLN A . n 
A 1 549 TRP 549 549 549 TRP TRP A . n 
A 1 550 VAL 550 550 550 VAL VAL A . n 
A 1 551 ILE 551 551 551 ILE ILE A . n 
A 1 552 ASP 552 552 552 ASP ASP A . n 
A 1 553 ILE 553 553 553 ILE ILE A . n 
A 1 554 THR 554 554 554 THR THR A . n 
A 1 555 VAL 555 555 555 VAL VAL A . n 
A 1 556 ASP 556 556 556 ASP ASP A . n 
A 1 557 LYS 557 557 557 LYS LYS A . n 
A 1 558 ASN 558 558 558 ASN ASN A . n 
A 1 559 MET 559 559 559 MET MET A . n 
A 1 560 PRO 560 560 560 PRO PRO A . n 
A 1 561 LYS 561 561 561 LYS LYS A . n 
A 1 562 PHE 562 562 562 PHE PHE A . n 
A 1 563 ASN 563 563 563 ASN ASN A . n 
A 1 564 GLU 564 564 ?   ?   ?   A . n 
A 1 565 ASN 565 565 ?   ?   ?   A . n 
A 1 566 LEU 566 566 ?   ?   ?   A . n 
A 1 567 TYR 567 567 ?   ?   ?   A . n 
A 1 568 PHE 568 568 ?   ?   ?   A . n 
A 1 569 GLN 569 569 ?   ?   ?   A . n 
B 2 1   GLY 1   84  ?   ?   ?   B . n 
B 2 2   ASN 2   85  ?   ?   ?   B . n 
B 2 3   LEU 3   86  ?   ?   ?   B . n 
B 2 4   GLY 4   87  87  GLY GLY B . n 
B 2 5   ASN 5   88  88  ASN ASN B . n 
B 2 6   THR 6   89  89  THR THR B . n 
B 2 7   CYS 7   90  90  CYS CYS B . n 
B 2 8   TYR 8   91  91  TYR TYR B . n 
B 2 9   LEU 9   92  92  LEU LEU B . n 
B 2 10  ASN 10  93  93  ASN ASN B . n 
B 2 11  SER 11  94  94  SER SER B . n 
B 2 12  ILE 12  95  95  ILE ILE B . n 
B 2 13  LEU 13  96  96  LEU LEU B . n 
B 2 14  GLN 14  97  97  GLN GLN B . n 
B 2 15  VAL 15  98  98  VAL VAL B . n 
B 2 16  LEU 16  99  99  LEU LEU B . n 
B 2 17  TYR 17  100 100 TYR TYR B . n 
B 2 18  PHE 18  101 101 PHE PHE B . n 
B 2 19  CYS 19  102 102 CYS CYS B . n 
B 2 20  PRO 20  103 103 PRO PRO B . n 
B 2 21  GLY 21  104 104 GLY GLY B . n 
B 2 22  PHE 22  105 105 PHE PHE B . n 
B 2 23  LYS 23  106 106 LYS LYS B . n 
B 2 24  SER 24  107 107 SER SER B . n 
B 2 25  GLY 25  108 108 GLY GLY B . n 
B 2 26  VAL 26  109 109 VAL VAL B . n 
B 2 27  LYS 27  110 110 LYS LYS B . n 
B 2 28  HIS 28  111 111 HIS HIS B . n 
B 2 29  LEU 29  112 112 LEU LEU B . n 
B 2 30  PHE 30  113 113 PHE PHE B . n 
B 2 31  ASN 31  114 114 ASN ASN B . n 
B 2 32  ILE 32  115 115 ILE ILE B . n 
B 2 33  ILE 33  116 116 ILE ILE B . n 
B 2 34  SER 34  117 117 SER SER B . n 
B 2 35  ARG 35  118 118 ARG ARG B . n 
B 2 36  LYS 36  119 119 LYS LYS B . n 
B 2 37  LYS 37  120 120 LYS LYS B . n 
B 2 38  GLU 38  121 121 GLU GLU B . n 
B 2 39  ALA 39  122 122 ALA ALA B . n 
B 2 40  LEU 40  123 123 LEU LEU B . n 
B 2 41  LYS 41  124 124 LYS LYS B . n 
B 2 42  ASP 42  125 125 ASP ASP B . n 
B 2 43  GLU 43  126 126 GLU GLU B . n 
B 2 44  ALA 44  127 ?   ?   ?   B . n 
B 2 45  ASN 45  128 ?   ?   ?   B . n 
B 2 46  GLN 46  129 ?   ?   ?   B . n 
B 2 47  LYS 47  130 ?   ?   ?   B . n 
B 2 48  ASP 48  131 ?   ?   ?   B . n 
B 2 49  LYS 49  132 ?   ?   ?   B . n 
B 2 50  GLY 50  133 ?   ?   ?   B . n 
B 2 51  ASN 51  134 134 ASN ASN B . n 
B 2 52  CYS 52  135 135 CYS CYS B . n 
B 2 53  LYS 53  136 136 LYS LYS B . n 
B 2 54  GLU 54  137 137 GLU GLU B . n 
B 2 55  ASP 55  138 138 ASP ASP B . n 
B 2 56  SER 56  139 139 SER SER B . n 
B 2 57  LEU 57  140 140 LEU LEU B . n 
B 2 58  ALA 58  141 141 ALA ALA B . n 
B 2 59  SER 59  142 142 SER SER B . n 
B 2 60  TYR 60  143 143 TYR TYR B . n 
B 2 61  GLU 61  144 144 GLU GLU B . n 
B 2 62  LEU 62  145 145 LEU LEU B . n 
B 2 63  ILE 63  146 146 ILE ILE B . n 
B 2 64  CYS 64  147 147 CYS CYS B . n 
B 2 65  SER 65  148 148 SER SER B . n 
B 2 66  LEU 66  149 149 LEU LEU B . n 
B 2 67  GLN 67  150 150 GLN GLN B . n 
B 2 68  SER 68  151 151 SER SER B . n 
B 2 69  LEU 69  152 152 LEU LEU B . n 
B 2 70  ILE 70  153 153 ILE ILE B . n 
B 2 71  ILE 71  154 154 ILE ILE B . n 
B 2 72  SER 72  155 155 SER SER B . n 
B 2 73  VAL 73  156 156 VAL VAL B . n 
B 2 74  GLU 74  157 157 GLU GLU B . n 
B 2 75  GLN 75  158 158 GLN GLN B . n 
B 2 76  LEU 76  159 159 LEU LEU B . n 
B 2 77  GLN 77  160 160 GLN GLN B . n 
B 2 78  ALA 78  161 161 ALA ALA B . n 
B 2 79  SER 79  162 162 SER SER B . n 
B 2 80  PHE 80  163 163 PHE PHE B . n 
B 2 81  LEU 81  164 164 LEU LEU B . n 
B 2 82  LEU 82  165 165 LEU LEU B . n 
B 2 83  ASN 83  166 166 ASN ASN B . n 
B 2 84  PRO 84  167 167 PRO PRO B . n 
B 2 85  GLU 85  168 168 GLU ALA B . n 
B 2 86  LYS 86  169 169 LYS ALA B . n 
B 2 87  TYR 87  170 170 TYR TYR B . n 
B 2 88  THR 88  171 171 THR THR B . n 
B 2 89  ASP 89  172 172 ASP ASP B . n 
B 2 90  GLU 90  173 173 GLU GLU B . n 
B 2 91  LEU 91  174 174 LEU LEU B . n 
B 2 92  ALA 92  175 175 ALA ALA B . n 
B 2 93  THR 93  176 176 THR THR B . n 
B 2 94  GLN 94  177 177 GLN GLN B . n 
B 2 95  PRO 95  178 178 PRO PRO B . n 
B 2 96  ARG 96  179 179 ARG ARG B . n 
B 2 97  ARG 97  180 180 ARG ARG B . n 
B 2 98  LEU 98  181 181 LEU LEU B . n 
B 2 99  LEU 99  182 182 LEU LEU B . n 
B 2 100 ASN 100 183 183 ASN ASN B . n 
B 2 101 THR 101 184 184 THR THR B . n 
B 2 102 LEU 102 185 185 LEU LEU B . n 
B 2 103 ARG 103 186 186 ARG ARG B . n 
B 2 104 GLU 104 187 187 GLU GLU B . n 
B 2 105 LEU 105 188 188 LEU LEU B . n 
B 2 106 ASN 106 189 189 ASN ASN B . n 
B 2 107 PRO 107 190 190 PRO PRO B . n 
B 2 108 MET 108 191 191 MET MET B . n 
B 2 109 TYR 109 192 192 TYR TYR B . n 
B 2 110 GLU 110 193 ?   ?   ?   B . n 
B 2 111 GLY 111 194 ?   ?   ?   B . n 
B 2 112 TYR 112 195 ?   ?   ?   B . n 
B 2 113 LEU 113 196 196 LEU LEU B . n 
B 2 114 GLN 114 197 197 GLN GLN B . n 
B 2 115 HIS 115 198 198 HIS HIS B . n 
B 2 116 ASP 116 199 199 ASP ASP B . n 
B 2 117 ALA 117 200 200 ALA ALA B . n 
B 2 118 GLN 118 201 201 GLN GLN B . n 
B 2 119 GLU 119 202 202 GLU GLU B . n 
B 2 120 VAL 120 203 203 VAL VAL B . n 
B 2 121 LEU 121 204 204 LEU LEU B . n 
B 2 122 GLN 122 205 205 GLN GLN B . n 
B 2 123 CYS 123 206 206 CYS CYS B . n 
B 2 124 ILE 124 207 207 ILE ILE B . n 
B 2 125 LEU 125 208 208 LEU LEU B . n 
B 2 126 GLY 126 209 209 GLY GLY B . n 
B 2 127 ASN 127 210 210 ASN ASN B . n 
B 2 128 ILE 128 211 211 ILE ILE B . n 
B 2 129 GLN 129 212 212 GLN GLN B . n 
B 2 130 GLU 130 213 213 GLU GLU B . n 
B 2 131 THR 131 214 214 THR THR B . n 
B 2 132 CYS 132 215 215 CYS CYS B . n 
B 2 133 GLN 133 216 216 GLN GLN B . n 
B 2 134 LEU 134 217 217 LEU LEU B . n 
B 2 135 LEU 135 218 218 LEU LEU B . n 
B 2 136 LYS 136 219 219 LYS LYS B . n 
B 2 137 LYS 137 220 220 LYS LYS B . n 
B 2 138 GLU 138 221 221 GLU GLU B . n 
B 2 139 GLU 139 222 222 GLU GLU B . n 
B 2 140 GLY 140 223 223 GLY GLY B . n 
B 2 141 SER 141 224 224 SER SER B . n 
B 2 142 GLY 142 225 225 GLY GLY B . n 
B 2 143 SER 143 414 ?   ?   ?   B . n 
B 2 144 GLY 144 415 ?   ?   ?   B . n 
B 2 145 SER 145 416 ?   ?   ?   B . n 
B 2 146 GLY 146 417 ?   ?   ?   B . n 
B 2 147 SER 147 418 ?   ?   ?   B . n 
B 2 148 GLY 148 419 ?   ?   ?   B . n 
B 2 149 SER 149 420 ?   ?   ?   B . n 
B 2 150 ILE 150 421 421 ILE ILE B . n 
B 2 151 GLY 151 422 422 GLY GLY B . n 
B 2 152 PHE 152 423 423 PHE PHE B . n 
B 2 153 GLU 153 424 424 GLU GLU B . n 
B 2 154 LEU 154 425 425 LEU LEU B . n 
B 2 155 VAL 155 426 426 VAL VAL B . n 
B 2 156 GLU 156 427 427 GLU GLU B . n 
B 2 157 LYS 157 428 428 LYS LYS B . n 
B 2 158 LEU 158 429 429 LEU LEU B . n 
B 2 159 PHE 159 430 430 PHE PHE B . n 
B 2 160 GLN 160 431 431 GLN GLN B . n 
B 2 161 GLY 161 432 432 GLY GLY B . n 
B 2 162 GLN 162 433 433 GLN GLN B . n 
B 2 163 LEU 163 434 434 LEU LEU B . n 
B 2 164 VAL 164 435 435 VAL VAL B . n 
B 2 165 LEU 165 436 436 LEU LEU B . n 
B 2 166 ARG 166 437 437 ARG ARG B . n 
B 2 167 THR 167 438 438 THR THR B . n 
B 2 168 ARG 168 439 439 ARG ARG B . n 
B 2 169 CYS 169 440 440 CYS CYS B . n 
B 2 170 LEU 170 441 441 LEU LEU B . n 
B 2 171 GLU 171 442 442 GLU GLU B . n 
B 2 172 CYS 172 443 443 CYS CYS B . n 
B 2 173 GLU 173 444 444 GLU GLU B . n 
B 2 174 SER 174 445 445 SER SER B . n 
B 2 175 LEU 175 446 446 LEU LEU B . n 
B 2 176 THR 176 447 447 THR THR B . n 
B 2 177 GLU 177 448 448 GLU GLU B . n 
B 2 178 ARG 178 449 449 ARG ARG B . n 
B 2 179 ARG 179 450 450 ARG ARG B . n 
B 2 180 GLU 180 451 451 GLU GLU B . n 
B 2 181 ASP 181 452 452 ASP ASP B . n 
B 2 182 PHE 182 453 453 PHE PHE B . n 
B 2 183 GLN 183 454 454 GLN GLN B . n 
B 2 184 ASP 184 455 455 ASP ASP B . n 
B 2 185 ILE 185 456 456 ILE ILE B . n 
B 2 186 SER 186 457 457 SER SER B . n 
B 2 187 VAL 187 458 458 VAL VAL B . n 
B 2 188 PRO 188 459 459 PRO PRO B . n 
B 2 189 VAL 189 460 460 VAL VAL B . n 
B 2 190 GLN 190 461 461 GLN GLN B . n 
B 2 191 GLU 191 462 462 GLU GLU B . n 
B 2 192 ASP 192 463 463 ASP ASP B . n 
B 2 193 GLU 193 464 ?   ?   ?   B . n 
B 2 194 LEU 194 465 ?   ?   ?   B . n 
B 2 195 SER 195 466 ?   ?   ?   B . n 
B 2 196 LYS 196 467 ?   ?   ?   B . n 
B 2 197 VAL 197 468 ?   ?   ?   B . n 
B 2 198 GLU 198 469 ?   ?   ?   B . n 
B 2 199 GLU 199 470 ?   ?   ?   B . n 
B 2 200 SER 200 471 ?   ?   ?   B . n 
B 2 201 SER 201 472 ?   ?   ?   B . n 
B 2 202 GLU 202 473 ?   ?   ?   B . n 
B 2 203 ILE 203 474 ?   ?   ?   B . n 
B 2 204 SER 204 475 ?   ?   ?   B . n 
B 2 205 PRO 205 476 ?   ?   ?   B . n 
B 2 206 GLU 206 477 ?   ?   ?   B . n 
B 2 207 PRO 207 478 ?   ?   ?   B . n 
B 2 208 LYS 208 479 ?   ?   ?   B . n 
B 2 209 THR 209 480 ?   ?   ?   B . n 
B 2 210 GLU 210 481 481 GLU GLU B . n 
B 2 211 MET 211 482 482 MET MET B . n 
B 2 212 LYS 212 483 483 LYS LYS B . n 
B 2 213 THR 213 484 484 THR THR B . n 
B 2 214 LEU 214 485 485 LEU LEU B . n 
B 2 215 ARG 215 486 486 ARG ARG B . n 
B 2 216 TRP 216 487 487 TRP TRP B . n 
B 2 217 ALA 217 488 488 ALA ALA B . n 
B 2 218 ILE 218 489 489 ILE ILE B . n 
B 2 219 SER 219 490 490 SER SER B . n 
B 2 220 GLN 220 491 491 GLN GLN B . n 
B 2 221 PHE 221 492 492 PHE PHE B . n 
B 2 222 ALA 222 493 493 ALA ALA B . n 
B 2 223 SER 223 494 494 SER SER B . n 
B 2 224 VAL 224 495 495 VAL VAL B . n 
B 2 225 GLU 225 496 496 GLU GLU B . n 
B 2 226 ARG 226 497 497 ARG ARG B . n 
B 2 227 ILE 227 498 498 ILE ILE B . n 
B 2 228 VAL 228 499 499 VAL VAL B . n 
B 2 229 GLY 229 500 500 GLY GLY B . n 
B 2 230 GLU 230 501 501 GLU GLU B . n 
B 2 231 ASP 231 502 502 ASP ASP B . n 
B 2 232 LYS 232 503 503 LYS LYS B . n 
B 2 233 TYR 233 504 504 TYR TYR B . n 
B 2 234 PHE 234 505 505 PHE PHE B . n 
B 2 235 CYS 235 506 506 CYS CYS B . n 
B 2 236 GLU 236 507 507 GLU GLU B . n 
B 2 237 ASN 237 508 508 ASN ASN B . n 
B 2 238 CYS 238 509 509 CYS CYS B . n 
B 2 239 HIS 239 510 510 HIS HIS B . n 
B 2 240 HIS 240 511 511 HIS HIS B . n 
B 2 241 TYR 241 512 512 TYR TYR B . n 
B 2 242 THR 242 513 513 THR THR B . n 
B 2 243 GLU 243 514 514 GLU GLU B . n 
B 2 244 ALA 244 515 515 ALA ALA B . n 
B 2 245 GLU 245 516 516 GLU GLU B . n 
B 2 246 ARG 246 517 517 ARG ARG B . n 
B 2 247 SER 247 518 518 SER SER B . n 
B 2 248 LEU 248 519 519 LEU LEU B . n 
B 2 249 LEU 249 520 520 LEU LEU B . n 
B 2 250 PHE 250 521 521 PHE PHE B . n 
B 2 251 ASP 251 522 522 ASP ASP B . n 
B 2 252 LYS 252 523 523 LYS LYS B . n 
B 2 253 MET 253 524 524 MET MET B . n 
B 2 254 PRO 254 525 525 PRO PRO B . n 
B 2 255 GLU 255 526 526 GLU GLU B . n 
B 2 256 VAL 256 527 527 VAL VAL B . n 
B 2 257 ILE 257 528 528 ILE ILE B . n 
B 2 258 THR 258 529 529 THR THR B . n 
B 2 259 ILE 259 530 530 ILE ILE B . n 
B 2 260 HIS 260 531 531 HIS HIS B . n 
B 2 261 LEU 261 532 532 LEU LEU B . n 
B 2 262 LYS 262 533 533 LYS LYS B . n 
B 2 263 CYS 263 534 534 CYS CYS B . n 
B 2 264 PHE 264 535 ?   ?   ?   B . n 
B 2 265 ALA 265 536 ?   ?   ?   B . n 
B 2 266 ALA 266 537 ?   ?   ?   B . n 
B 2 267 SER 267 538 ?   ?   ?   B . n 
B 2 268 GLY 268 539 ?   ?   ?   B . n 
B 2 269 LEU 269 540 ?   ?   ?   B . n 
B 2 270 GLU 270 541 ?   ?   ?   B . n 
B 2 271 PHE 271 542 ?   ?   ?   B . n 
B 2 272 ASP 272 543 ?   ?   ?   B . n 
B 2 273 CYS 273 544 ?   ?   ?   B . n 
B 2 274 TYR 274 545 ?   ?   ?   B . n 
B 2 275 GLY 275 546 ?   ?   ?   B . n 
B 2 276 GLY 276 547 ?   ?   ?   B . n 
B 2 277 GLY 277 548 ?   ?   ?   B . n 
B 2 278 LEU 278 549 ?   ?   ?   B . n 
B 2 279 SER 279 550 ?   ?   ?   B . n 
B 2 280 LYS 280 551 551 LYS LYS B . n 
B 2 281 ILE 281 552 552 ILE ILE B . n 
B 2 282 ASN 282 553 553 ASN ASN B . n 
B 2 283 THR 283 554 554 THR THR B . n 
B 2 284 PRO 284 555 555 PRO PRO B . n 
B 2 285 LEU 285 556 556 LEU LEU B . n 
B 2 286 LEU 286 557 557 LEU LEU B . n 
B 2 287 THR 287 558 558 THR THR B . n 
B 2 288 PRO 288 559 559 PRO PRO B . n 
B 2 289 LEU 289 560 560 LEU LEU B . n 
B 2 290 LYS 290 561 561 LYS LYS B . n 
B 2 291 LEU 291 562 562 LEU LEU B . n 
B 2 292 SER 292 563 563 SER SER B . n 
B 2 293 LEU 293 564 564 LEU LEU B . n 
B 2 294 GLU 294 565 565 GLU GLU B . n 
B 2 295 GLU 295 566 566 GLU GLU B . n 
B 2 296 TRP 296 567 567 TRP TRP B . n 
B 2 297 SER 297 568 568 SER SER B . n 
B 2 298 THR 298 569 569 THR THR B . n 
B 2 299 LYS 299 570 570 LYS LYS B . n 
B 2 300 PRO 300 571 571 PRO PRO B . n 
B 2 301 THR 301 572 572 THR THR B . n 
B 2 302 ASN 302 573 573 ASN ASN B . n 
B 2 303 ASP 303 574 574 ASP ASP B . n 
B 2 304 SER 304 575 575 SER SER B . n 
B 2 305 TYR 305 576 576 TYR TYR B . n 
B 2 306 GLY 306 577 577 GLY GLY B . n 
B 2 307 LEU 307 578 578 LEU LEU B . n 
B 2 308 PHE 308 579 579 PHE PHE B . n 
B 2 309 ALA 309 580 580 ALA ALA B . n 
B 2 310 VAL 310 581 581 VAL VAL B . n 
B 2 311 VAL 311 582 582 VAL VAL B . n 
B 2 312 MET 312 583 583 MET MET B . n 
B 2 313 HIS 313 584 584 HIS HIS B . n 
B 2 314 SER 314 585 585 SER SER B . n 
B 2 315 GLY 315 586 586 GLY GLY B . n 
B 2 316 ILE 316 587 587 ILE ILE B . n 
B 2 317 THR 317 588 588 THR THR B . n 
B 2 318 ILE 318 589 589 ILE ILE B . n 
B 2 319 SER 319 590 590 SER SER B . n 
B 2 320 SER 320 591 591 SER SER B . n 
B 2 321 GLY 321 592 592 GLY GLY B . n 
B 2 322 HIS 322 593 593 HIS HIS B . n 
B 2 323 TYR 323 594 594 TYR TYR B . n 
B 2 324 THR 324 595 595 THR THR B . n 
B 2 325 ALA 325 596 596 ALA ALA B . n 
B 2 326 SER 326 597 597 SER SER B . n 
B 2 327 VAL 327 598 598 VAL VAL B . n 
B 2 328 LYS 328 599 599 LYS LYS B . n 
B 2 329 VAL 329 600 600 VAL VAL B . n 
B 2 330 THR 330 601 601 THR THR B . n 
B 2 331 ASP 331 602 602 ASP ASP B . n 
B 2 332 LEU 332 603 603 LEU LEU B . n 
B 2 333 ASN 333 604 604 ASN ASN B . n 
B 2 334 SER 334 605 605 SER SER B . n 
B 2 335 SER 335 739 739 SER SER B . n 
B 2 336 LEU 336 740 740 LEU LEU B . n 
B 2 337 LYS 337 741 741 LYS LYS B . n 
B 2 338 GLU 338 742 742 GLU GLU B . n 
B 2 339 TYR 339 743 743 TYR TYR B . n 
B 2 340 GLU 340 744 744 GLU GLU B . n 
B 2 341 GLY 341 745 745 GLY GLY B . n 
B 2 342 LYS 342 746 746 LYS LYS B . n 
B 2 343 TRP 343 747 747 TRP TRP B . n 
B 2 344 LEU 344 748 748 LEU LEU B . n 
B 2 345 LEU 345 749 749 LEU LEU B . n 
B 2 346 PHE 346 750 750 PHE PHE B . n 
B 2 347 ASP 347 751 751 ASP ASP B . n 
B 2 348 ASP 348 752 752 ASP ASP B . n 
B 2 349 SER 349 753 753 SER SER B . n 
B 2 350 GLU 350 754 754 GLU GLU B . n 
B 2 351 VAL 351 755 755 VAL VAL B . n 
B 2 352 LYS 352 756 756 LYS LYS B . n 
B 2 353 VAL 353 757 757 VAL VAL B . n 
B 2 354 THR 354 758 758 THR THR B . n 
B 2 355 GLU 355 759 759 GLU GLU B . n 
B 2 356 GLU 356 760 760 GLU GLU B . n 
B 2 357 LYS 357 761 761 LYS LYS B . n 
B 2 358 ASP 358 762 762 ASP ASP B . n 
B 2 359 PHE 359 763 763 PHE PHE B . n 
B 2 360 LEU 360 764 764 LEU LEU B . n 
B 2 361 ASN 361 765 765 ASN ASN B . n 
B 2 362 SER 362 766 766 SER SER B . n 
B 2 363 LEU 363 767 767 LEU LEU B . n 
B 2 364 SER 364 768 768 SER SER B . n 
B 2 365 PRO 365 769 769 PRO PRO B . n 
B 2 366 SER 366 770 ?   ?   ?   B . n 
B 2 367 THR 367 771 ?   ?   ?   B . n 
B 2 368 SER 368 772 ?   ?   ?   B . n 
B 2 369 PRO 369 773 773 PRO PRO B . n 
B 2 370 THR 370 774 774 THR THR B . n 
B 2 371 SER 371 775 775 SER SER B . n 
B 2 372 THR 372 776 776 THR THR B . n 
B 2 373 PRO 373 777 777 PRO PRO B . n 
B 2 374 TYR 374 778 778 TYR TYR B . n 
B 2 375 LEU 375 779 779 LEU LEU B . n 
B 2 376 LEU 376 780 780 LEU LEU B . n 
B 2 377 PHE 377 781 781 PHE PHE B . n 
B 2 378 TYR 378 782 782 TYR TYR B . n 
B 2 379 LYS 379 783 783 LYS LYS B . n 
B 2 380 LYS 380 784 784 LYS LYS B . n 
B 2 381 LEU 381 785 785 LEU LEU B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1BWW 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1BWW 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 ZN    1 801 1  ZN    ZN  B . 
D 4 A1BWW 1 802 1  A1BWW LIG B . 
E 5 HOH   1 601 8  HOH   HOH A . 
E 5 HOH   2 602 7  HOH   HOH A . 
E 5 HOH   3 603 2  HOH   HOH A . 
E 5 HOH   4 604 10 HOH   HOH A . 
E 5 HOH   5 605 4  HOH   HOH A . 
E 5 HOH   6 606 3  HOH   HOH A . 
E 5 HOH   7 607 6  HOH   HOH A . 
F 5 HOH   1 901 9  HOH   HOH B . 
F 5 HOH   2 902 5  HOH   HOH B . 
F 5 HOH   3 903 1  HOH   HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B GLU 168 ? CG  ? B GLU 85 CG  
2 1 Y 1 B GLU 168 ? CD  ? B GLU 85 CD  
3 1 Y 1 B GLU 168 ? OE1 ? B GLU 85 OE1 
4 1 Y 1 B GLU 168 ? OE2 ? B GLU 85 OE2 
5 1 Y 1 B LYS 169 ? CG  ? B LYS 86 CG  
6 1 Y 1 B LYS 169 ? CD  ? B LYS 86 CD  
7 1 Y 1 B LYS 169 ? CE  ? B LYS 86 CE  
8 1 Y 1 B LYS 169 ? NZ  ? B LYS 86 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20.1_4487 1 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0267    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           3 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           4 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           5 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9N9Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     123.200 
_cell.length_a_esd                 ? 
_cell.length_b                     161.880 
_cell.length_b_esd                 ? 
_cell.length_c                     160.480 
_cell.length_c_esd                 ? 
_cell.volume                       3200551.496 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9N9Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                23 
_symmetry.space_group_name_Hall            'I 2 2' 
_symmetry.space_group_name_H-M             'I 2 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9N9Y 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.74 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          67.11 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '1M sodium citrate (pH 6.5)' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-08-15 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.18064 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'CLSI BEAMLINE 08B1-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.18064 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   08B1-1 
_diffrn_source.pdbx_synchrotron_site       CLSI 
# 
_reflns.B_iso_Wilson_estimate                          87.01 
_reflns.entry_id                                       9N9Y 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.15 
_reflns.d_resolution_low                               49.43 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     13245 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           46.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.4 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.095 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
3.15 3.37  ? 3.6  ? ? ? ? 193  ? ? ? ? ? ? ? ? ? ? ? ?   ? ? ? ? ? ? 1 1 0.876 ? ? ? ? 0.434 ? ? ? ? ? ? ? ? ? 
8.91 49.43 ? 36.5 ? ? ? ? 1339 ? ? ? ? ? ? ? ? ? ? ? 5.9 ? ? ? ? ? ? 2 1 0.999 ? ? ? ? 0.031 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               83.98 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9N9Y 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.15 
_refine.ls_d_res_low                             49.43 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     13237 
_refine.ls_number_reflns_R_free                  677 
_refine.ls_number_reflns_R_work                  12560 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    47.13 
_refine.ls_percent_reflns_R_free                 5.11 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2399 
_refine.ls_R_factor_R_free                       0.2915 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2371 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 34.2497 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.4099 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.15 
_refine_hist.d_res_low                        49.43 
_refine_hist.number_atoms_solvent             10 
_refine_hist.number_atoms_total               6739 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6691 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         38 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0017  ? 6860 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.4751  ? 9297 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0408  ? 1063 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0033  ? 1173 ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 11.6778 ? 2528 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.15 3.39  . . 9   220  4.14  . . . . 0.4019 . . . . . . . . . . . 0.4139 
'X-RAY DIFFRACTION' 3.40 3.74  . . 43  746  14.25 . . . . 0.3139 . . . . . . . . . . . 0.3542 
'X-RAY DIFFRACTION' 3.74 4.28  . . 122 1823 35.00 . . . . 0.2510 . . . . . . . . . . . 0.3570 
'X-RAY DIFFRACTION' 4.28 5.39  . . 211 4274 79.75 . . . . 0.2333 . . . . . . . . . . . 0.2961 
'X-RAY DIFFRACTION' 5.39 49.43 . . 292 5497 99.79 . . . . 0.2313 . . . . . . . . . . . 0.2693 
# 
_struct.entry_id                     9N9Y 
_struct.title                        'Crystal structure of truncated USP1:UAF1 in complex with compound 18' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9N9Y 
_struct_keywords.text            'ubiquitin, cysteine protease, allosteric inhibitor, HYDROLASE, HYDROLASE-INHIBITOR complex' 
_struct_keywords.pdbx_keywords   HYDROLASE/INHIBITOR 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP WDR48_HUMAN Q8TAF3 ? 1 
;MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVND
IVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKST
VNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMP
KFN
;
1   
2 UNP UBP1_HUMAN  O94782 ? 2 
;NLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFL
LNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEE
;
85  
3 UNP UBP1_HUMAN  O94782 ? 2 
;IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVG
EDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFA
VVMHSGITISSGHYTASVKVTDLNS
;
421 
4 UNP UBP1_HUMAN  O94782 ? 2 SLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL 739 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9N9Y A 1   ? 563 ? Q8TAF3 1   ? 563 ? 1   563 
2 2 9N9Y B 2   ? 139 ? O94782 85  ? 222 ? 85  222 
3 3 9N9Y B 150 ? 334 ? O94782 421 ? 605 ? 421 605 
4 4 9N9Y B 335 ? 381 ? O94782 739 ? 785 ? 739 785 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9N9Y GLU A 564 ? UNP Q8TAF3 ? ? 'expression tag' 564 1  
1 9N9Y ASN A 565 ? UNP Q8TAF3 ? ? 'expression tag' 565 2  
1 9N9Y LEU A 566 ? UNP Q8TAF3 ? ? 'expression tag' 566 3  
1 9N9Y TYR A 567 ? UNP Q8TAF3 ? ? 'expression tag' 567 4  
1 9N9Y PHE A 568 ? UNP Q8TAF3 ? ? 'expression tag' 568 5  
1 9N9Y GLN A 569 ? UNP Q8TAF3 ? ? 'expression tag' 569 6  
2 9N9Y GLY B 1   ? UNP O94782 ? ? 'expression tag' 84  7  
2 9N9Y GLY B 140 ? UNP O94782 ? ? linker           223 8  
2 9N9Y SER B 141 ? UNP O94782 ? ? linker           224 9  
2 9N9Y GLY B 142 ? UNP O94782 ? ? linker           225 10 
2 9N9Y SER B 143 ? UNP O94782 ? ? linker           414 11 
2 9N9Y GLY B 144 ? UNP O94782 ? ? linker           415 12 
2 9N9Y SER B 145 ? UNP O94782 ? ? linker           416 13 
2 9N9Y GLY B 146 ? UNP O94782 ? ? linker           417 14 
2 9N9Y SER B 147 ? UNP O94782 ? ? linker           418 15 
2 9N9Y GLY B 148 ? UNP O94782 ? ? linker           419 16 
2 9N9Y SER B 149 ? UNP O94782 ? ? linker           420 17 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 146 ? ALA A 151 ? VAL A 146 ALA A 151 1 ? 6  
HELX_P HELX_P2  AA2 ASP A 402 ? ARG A 410 ? ASP A 402 ARG A 410 1 ? 9  
HELX_P HELX_P3  AA3 LEU A 462 ? LEU A 471 ? LEU A 462 LEU A 471 1 ? 10 
HELX_P HELX_P4  AA4 ARG A 531 ? GLY A 534 ? ARG A 531 GLY A 534 5 ? 4  
HELX_P HELX_P5  AA5 GLY A 535 ? VAL A 546 ? GLY A 535 VAL A 546 1 ? 12 
HELX_P HELX_P6  AA6 PRO A 547 ? VAL A 555 ? PRO A 547 VAL A 555 1 ? 9  
HELX_P HELX_P7  AA7 THR B 6   ? PHE B 18  ? THR B 89  PHE B 101 1 ? 13 
HELX_P HELX_P8  AA8 GLY B 21  ? GLU B 43  ? GLY B 104 GLU B 126 1 ? 23 
HELX_P HELX_P9  AA9 LYS B 53  ? PHE B 80  ? LYS B 136 PHE B 163 1 ? 28 
HELX_P HELX_P10 AB1 ASN B 83  ? THR B 88  ? ASN B 166 THR B 171 5 ? 6  
HELX_P HELX_P11 AB2 ASP B 89  ? LEU B 105 ? ASP B 172 LEU B 188 1 ? 17 
HELX_P HELX_P12 AB3 ASP B 116 ? LYS B 137 ? ASP B 199 LYS B 220 1 ? 22 
HELX_P HELX_P13 AB4 THR B 213 ? SER B 223 ? THR B 484 SER B 494 1 ? 11 
HELX_P HELX_P14 AB5 GLU B 294 ? SER B 297 ? GLU B 565 SER B 568 5 ? 4  
HELX_P HELX_P15 AB6 THR B 317 ? GLY B 321 ? THR B 588 GLY B 592 5 ? 5  
HELX_P HELX_P16 AB7 GLU B 355 ? SER B 364 ? GLU B 759 SER B 768 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? B CYS 169 SG ? ? ? 1_555 C ZN . ZN ? ? B CYS 440 B ZN 801 1_555 ? ? ? ? ? ? ? 2.326 ? ? 
metalc2 metalc ? ? B CYS 172 SG ? ? ? 1_555 C ZN . ZN ? ? B CYS 443 B ZN 801 1_555 ? ? ? ? ? ? ? 2.325 ? ? 
metalc3 metalc ? ? B CYS 235 SG ? ? ? 1_555 C ZN . ZN ? ? B CYS 506 B ZN 801 1_555 ? ? ? ? ? ? ? 2.326 ? ? 
metalc4 metalc ? ? B CYS 238 SG ? ? ? 1_555 C ZN . ZN ? ? B CYS 509 B ZN 801 1_555 ? ? ? ? ? ? ? 2.330 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 SG ? B CYS 169 ? B CYS 440 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 172 ? B CYS 443 ? 1_555 108.4 ? 
2 SG ? B CYS 169 ? B CYS 440 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 235 ? B CYS 506 ? 1_555 102.9 ? 
3 SG ? B CYS 172 ? B CYS 443 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 235 ? B CYS 506 ? 1_555 113.9 ? 
4 SG ? B CYS 169 ? B CYS 440 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 238 ? B CYS 509 ? 1_555 115.7 ? 
5 SG ? B CYS 172 ? B CYS 443 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 238 ? B CYS 509 ? 1_555 106.3 ? 
6 SG ? B CYS 235 ? B CYS 506 ? 1_555 ZN ? C ZN . ? B ZN 801 ? 1_555 SG ? B CYS 238 ? B CYS 509 ? 1_555 109.7 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 3 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 7 ? 
AB6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB5 6 7 ? anti-parallel 
AB6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 421 ? ASP A 423 ? SER A 421 ASP A 423 
AA1 2 LEU A 429 ? ASP A 434 ? LEU A 429 ASP A 434 
AA1 3 VAL A 15  ? ILE A 21  ? VAL A 15  ILE A 21  
AA1 4 PRO A 514 ? GLU A 519 ? PRO A 514 GLU A 519 
AA1 5 THR A 524 ? LEU A 529 ? THR A 524 LEU A 529 
AA2 1 VAL A 33  ? ASP A 39  ? VAL A 33  ASP A 39  
AA2 2 ARG A 44  ? GLY A 49  ? ARG A 44  GLY A 49  
AA2 3 ILE A 54  ? SER A 58  ? ILE A 54  SER A 58  
AA2 4 TYR A 67  ? MET A 71  ? TYR A 67  MET A 71  
AA3 1 VAL A 78  ? CYS A 84  ? VAL A 78  CYS A 84  
AA3 2 THR A 89  ? SER A 94  ? THR A 89  SER A 94  
AA3 3 VAL A 99  ? ASN A 103 ? VAL A 99  ASN A 103 
AA3 4 PHE A 108 ? LEU A 113 ? PHE A 108 LEU A 113 
AA4 1 VAL A 120 ? ALA A 126 ? VAL A 120 ALA A 126 
AA4 2 LEU A 131 ? GLY A 136 ? LEU A 131 GLY A 136 
AA4 3 ILE A 141 ? ASP A 145 ? ILE A 141 ASP A 145 
AA5 1 ILE A 171 ? MET A 176 ? ILE A 171 MET A 176 
AA5 2 ILE A 183 ? SER A 187 ? ILE A 183 SER A 187 
AA5 3 LEU A 192 ? ASP A 196 ? LEU A 192 ASP A 196 
AA5 4 ALA A 201 ? LEU A 206 ? ALA A 201 LEU A 206 
AA6 1 VAL A 213 ? LEU A 218 ? VAL A 213 LEU A 218 
AA6 2 GLN A 224 ? SER A 229 ? GLN A 224 SER A 229 
AA6 3 ILE A 234 ? SER A 238 ? ILE A 234 SER A 238 
AA6 4 ARG A 243 ? TYR A 248 ? ARG A 243 TYR A 248 
AA7 1 VAL A 255 ? VAL A 260 ? VAL A 255 VAL A 260 
AA7 2 HIS A 266 ? GLY A 271 ? HIS A 266 GLY A 271 
AA7 3 LYS A 275 ? ASP A 280 ? LYS A 275 ASP A 280 
AA7 4 ASN A 283 ? GLU A 292 ? ASN A 283 GLU A 292 
AA8 1 VAL A 297 ? LEU A 302 ? VAL A 297 LEU A 302 
AA8 2 ALA A 311 ? THR A 316 ? ALA A 311 THR A 316 
AA8 3 VAL A 321 ? THR A 325 ? VAL A 321 THR A 325 
AA8 4 GLN A 355 ? ILE A 357 ? GLN A 355 ILE A 357 
AA9 1 GLN A 365 ? ILE A 368 ? GLN A 365 ILE A 368 
AA9 2 HIS A 374 ? LYS A 378 ? HIS A 374 LYS A 378 
AA9 3 VAL A 384 ? ASP A 388 ? VAL A 384 ASP A 388 
AA9 4 CYS A 393 ? GLY A 399 ? CYS A 393 GLY A 399 
AB1 1 TRP A 442 ? SER A 444 ? TRP A 442 SER A 444 
AB1 2 LYS A 459 ? ASN A 461 ? LYS A 459 ASN A 461 
AB2 1 ARG B 179 ? PHE B 182 ? ARG B 450 PHE B 453 
AB2 2 GLY B 161 ? VAL B 164 ? GLY B 432 VAL B 435 
AB2 3 LEU B 249 ? LYS B 252 ? LEU B 520 LYS B 523 
AB3 1 SER B 174 ? THR B 176 ? SER B 445 THR B 447 
AB3 2 THR B 167 ? CYS B 169 ? THR B 438 CYS B 440 
AB3 3 ALA B 244 ? ARG B 246 ? ALA B 515 ARG B 517 
AB3 4 GLU B 225 ? ILE B 227 ? GLU B 496 ILE B 498 
AB4 1 ASP B 184 ? VAL B 187 ? ASP B 455 VAL B 458 
AB4 2 VAL B 256 ? LEU B 261 ? VAL B 527 LEU B 532 
AB4 3 THR B 372 ? LYS B 380 ? THR B 776 LYS B 784 
AB4 4 SER B 304 ? SER B 314 ? SER B 575 SER B 585 
AB4 5 LYS B 290 ? SER B 292 ? LYS B 561 SER B 563 
AB5 1 ASP B 184 ? VAL B 187 ? ASP B 455 VAL B 458 
AB5 2 VAL B 256 ? LEU B 261 ? VAL B 527 LEU B 532 
AB5 3 THR B 372 ? LYS B 380 ? THR B 776 LYS B 784 
AB5 4 SER B 304 ? SER B 314 ? SER B 575 SER B 585 
AB5 5 HIS B 322 ? LYS B 328 ? HIS B 593 LYS B 599 
AB5 6 TRP B 343 ? ASP B 347 ? TRP B 747 ASP B 751 
AB5 7 GLU B 350 ? THR B 354 ? GLU B 754 THR B 758 
AB6 1 TYR B 233 ? CYS B 235 ? TYR B 504 CYS B 506 
AB6 2 HIS B 240 ? THR B 242 ? HIS B 511 THR B 513 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 421 ? N SER A 421 O THR A 432 ? O THR A 432 
AA1 2 3 O ILE A 431 ? O ILE A 431 N TYR A 19  ? N TYR A 19  
AA1 3 4 N GLN A 16  ? N GLN A 16  O GLY A 518 ? O GLY A 518 
AA1 4 5 N PHE A 517 ? N PHE A 517 O PHE A 526 ? O PHE A 526 
AA2 1 2 N ASP A 39  ? N ASP A 39  O ARG A 44  ? O ARG A 44  
AA2 2 3 N THR A 47  ? N THR A 47  O ARG A 55  ? O ARG A 55  
AA2 3 4 N ILE A 54  ? N ILE A 54  O MET A 71  ? O MET A 71  
AA3 1 2 N ASP A 80  ? N ASP A 80  O ALA A 93  ? O ALA A 93  
AA3 2 3 N LEU A 90  ? N LEU A 90  O TRP A 102 ? O TRP A 102 
AA3 3 4 N VAL A 101 ? N VAL A 101 O MET A 110 ? O MET A 110 
AA4 1 2 N ALA A 122 ? N ALA A 122 O ALA A 135 ? O ALA A 135 
AA4 2 3 N VAL A 132 ? N VAL A 132 O TRP A 144 ? O TRP A 144 
AA5 1 2 N TYR A 172 ? N TYR A 172 O GLY A 186 ? O GLY A 186 
AA5 2 3 N ILE A 183 ? N ILE A 183 O TRP A 195 ? O TRP A 195 
AA5 3 4 N VAL A 194 ? N VAL A 194 O LEU A 203 ? O LEU A 203 
AA6 1 2 N ALA A 215 ? N ALA A 215 O GLY A 228 ? O GLY A 228 
AA6 2 3 N CYS A 225 ? N CYS A 225 O TRP A 237 ? O TRP A 237 
AA6 3 4 N ILE A 234 ? N ILE A 234 O TYR A 248 ? O TYR A 248 
AA7 1 2 N GLN A 259 ? N GLN A 259 O TYR A 268 ? O TYR A 268 
AA7 2 3 N VAL A 267 ? N VAL A 267 O THR A 279 ? O THR A 279 
AA7 3 4 N ILE A 276 ? N ILE A 276 O ILE A 290 ? O ILE A 290 
AA8 1 2 N GLU A 301 ? N GLU A 301 O TRP A 313 ? O TRP A 313 
AA8 2 3 N VAL A 314 ? N VAL A 314 O ASN A 322 ? O ASN A 322 
AA8 3 4 N VAL A 321 ? N VAL A 321 O ILE A 357 ? O ILE A 357 
AA9 1 2 N HIS A 367 ? N HIS A 367 O LEU A 376 ? O LEU A 376 
AA9 2 3 N ILE A 375 ? N ILE A 375 O TRP A 387 ? O TRP A 387 
AA9 3 4 N TYR A 386 ? N TYR A 386 O VAL A 395 ? O VAL A 395 
AB1 1 2 N VAL A 443 ? N VAL A 443 O LEU A 460 ? O LEU A 460 
AB2 1 2 O GLU B 180 ? O GLU B 451 N LEU B 163 ? N LEU B 434 
AB2 2 3 N GLN B 162 ? N GLN B 433 O ASP B 251 ? O ASP B 522 
AB3 1 2 O THR B 176 ? O THR B 447 N THR B 167 ? N THR B 438 
AB3 2 3 N ARG B 168 ? N ARG B 439 O GLU B 245 ? O GLU B 516 
AB3 3 4 O ARG B 246 ? O ARG B 517 N GLU B 225 ? N GLU B 496 
AB4 1 2 N VAL B 187 ? N VAL B 458 O HIS B 260 ? O HIS B 531 
AB4 2 3 N ILE B 257 ? N ILE B 528 O TYR B 378 ? O TYR B 782 
AB4 3 4 O TYR B 374 ? O TYR B 778 N VAL B 311 ? N VAL B 582 
AB4 4 5 O TYR B 305 ? O TYR B 576 N LEU B 291 ? N LEU B 562 
AB5 1 2 N VAL B 187 ? N VAL B 458 O HIS B 260 ? O HIS B 531 
AB5 2 3 N ILE B 257 ? N ILE B 528 O TYR B 378 ? O TYR B 782 
AB5 3 4 O TYR B 374 ? O TYR B 778 N VAL B 311 ? N VAL B 582 
AB5 4 5 N MET B 312 ? N MET B 583 O THR B 324 ? O THR B 595 
AB5 5 6 N VAL B 327 ? N VAL B 598 O LEU B 344 ? O LEU B 748 
AB5 6 7 N ASP B 347 ? N ASP B 751 O GLU B 350 ? O GLU B 754 
AB6 1 2 N TYR B 233 ? N TYR B 504 O THR B 242 ? O THR B 513 
# 
_pdbx_entry_details.entry_id                   9N9Y 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 76  ? ? -112.17 -156.28 
2  1 ARG A 114 ? ? -104.07 58.86   
3  1 ASP A 118 ? ? -121.43 -156.78 
4  1 ALA A 151 ? ? -99.03  38.91   
5  1 VAL A 159 ? ? -168.83 110.73  
6  1 LYS A 207 ? ? -117.88 77.78   
7  1 GLU A 253 ? ? -109.11 -153.66 
8  1 ARG A 304 ? ? -109.66 47.28   
9  1 THR A 316 ? ? -113.21 -167.94 
10 1 ASN A 344 ? ? -133.40 -64.21  
11 1 PRO A 345 ? ? -83.96  -110.57 
12 1 PHE A 439 ? ? -97.98  32.00   
13 1 ASP A 457 ? ? -151.21 85.13   
14 1 LEU A 471 ? ? -93.33  30.88   
15 1 TYR A 506 ? ? -143.66 -41.61  
16 1 LYS A 561 ? ? 61.64   -176.34 
17 1 TYR B 170 ? ? -103.22 -62.14  
18 1 LEU B 429 ? ? -134.67 -45.27  
19 1 LEU B 436 ? ? -117.21 68.22   
20 1 GLU B 442 ? ? -76.43  -73.30  
21 1 SER B 494 ? ? -74.03  -164.30 
22 1 ASP B 522 ? ? -99.02  -62.06  
23 1 PRO B 571 ? ? -58.37  105.38  
24 1 ASN B 573 ? ? -92.60  35.47   
25 1 SER B 591 ? ? -144.11 47.84   
26 1 SER B 739 ? ? -160.50 -46.05  
27 1 ASP B 752 ? ? 55.79   -131.70 
28 1 THR B 774 ? ? -74.96  -77.60  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z             
4 -x,-y,z             
5 x+1/2,y+1/2,z+1/2   
6 x+1/2,-y+1/2,-z+1/2 
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ALA 2   ? A ALA 2   
3   1 Y 1 A ALA 3   ? A ALA 3   
4   1 Y 1 A HIS 4   ? A HIS 4   
5   1 Y 1 A HIS 5   ? A HIS 5   
6   1 Y 1 A ARG 6   ? A ARG 6   
7   1 Y 1 A GLN 7   ? A GLN 7   
8   1 Y 1 A ASN 8   ? A ASN 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A ALA 10  ? A ALA 10  
11  1 Y 1 A GLY 11  ? A GLY 11  
12  1 Y 1 A ARG 12  ? A ARG 12  
13  1 Y 1 A HIS 330 ? A HIS 330 
14  1 Y 1 A ASN 331 ? A ASN 331 
15  1 Y 1 A PHE 332 ? A PHE 332 
16  1 Y 1 A ARG 333 ? A ARG 333 
17  1 Y 1 A ALA 334 ? A ALA 334 
18  1 Y 1 A SER 335 ? A SER 335 
19  1 Y 1 A GLY 336 ? A GLY 336 
20  1 Y 1 A ASP 337 ? A ASP 337 
21  1 Y 1 A TYR 338 ? A TYR 338 
22  1 Y 1 A ASP 339 ? A ASP 339 
23  1 Y 1 A ASN 340 ? A ASN 340 
24  1 Y 1 A ASP 341 ? A ASP 341 
25  1 Y 1 A CYS 342 ? A CYS 342 
26  1 Y 1 A PRO 481 ? A PRO 481 
27  1 Y 1 A MET 482 ? A MET 482 
28  1 Y 1 A ASP 483 ? A ASP 483 
29  1 Y 1 A GLU 484 ? A GLU 484 
30  1 Y 1 A GLU 485 ? A GLU 485 
31  1 Y 1 A GLU 486 ? A GLU 486 
32  1 Y 1 A ASN 487 ? A ASN 487 
33  1 Y 1 A GLU 488 ? A GLU 488 
34  1 Y 1 A VAL 489 ? A VAL 489 
35  1 Y 1 A ASN 490 ? A ASN 490 
36  1 Y 1 A HIS 491 ? A HIS 491 
37  1 Y 1 A VAL 492 ? A VAL 492 
38  1 Y 1 A ASN 493 ? A ASN 493 
39  1 Y 1 A GLY 494 ? A GLY 494 
40  1 Y 1 A GLU 495 ? A GLU 495 
41  1 Y 1 A GLN 496 ? A GLN 496 
42  1 Y 1 A GLU 497 ? A GLU 497 
43  1 Y 1 A ASN 498 ? A ASN 498 
44  1 Y 1 A ARG 499 ? A ARG 499 
45  1 Y 1 A GLU 564 ? A GLU 564 
46  1 Y 1 A ASN 565 ? A ASN 565 
47  1 Y 1 A LEU 566 ? A LEU 566 
48  1 Y 1 A TYR 567 ? A TYR 567 
49  1 Y 1 A PHE 568 ? A PHE 568 
50  1 Y 1 A GLN 569 ? A GLN 569 
51  1 Y 1 B GLY 84  ? B GLY 1   
52  1 Y 1 B ASN 85  ? B ASN 2   
53  1 Y 1 B LEU 86  ? B LEU 3   
54  1 Y 1 B ALA 127 ? B ALA 44  
55  1 Y 1 B ASN 128 ? B ASN 45  
56  1 Y 1 B GLN 129 ? B GLN 46  
57  1 Y 1 B LYS 130 ? B LYS 47  
58  1 Y 1 B ASP 131 ? B ASP 48  
59  1 Y 1 B LYS 132 ? B LYS 49  
60  1 Y 1 B GLY 133 ? B GLY 50  
61  1 Y 1 B GLU 193 ? B GLU 110 
62  1 Y 1 B GLY 194 ? B GLY 111 
63  1 Y 1 B TYR 195 ? B TYR 112 
64  1 Y 1 B SER 414 ? B SER 143 
65  1 Y 1 B GLY 415 ? B GLY 144 
66  1 Y 1 B SER 416 ? B SER 145 
67  1 Y 1 B GLY 417 ? B GLY 146 
68  1 Y 1 B SER 418 ? B SER 147 
69  1 Y 1 B GLY 419 ? B GLY 148 
70  1 Y 1 B SER 420 ? B SER 149 
71  1 Y 1 B GLU 464 ? B GLU 193 
72  1 Y 1 B LEU 465 ? B LEU 194 
73  1 Y 1 B SER 466 ? B SER 195 
74  1 Y 1 B LYS 467 ? B LYS 196 
75  1 Y 1 B VAL 468 ? B VAL 197 
76  1 Y 1 B GLU 469 ? B GLU 198 
77  1 Y 1 B GLU 470 ? B GLU 199 
78  1 Y 1 B SER 471 ? B SER 200 
79  1 Y 1 B SER 472 ? B SER 201 
80  1 Y 1 B GLU 473 ? B GLU 202 
81  1 Y 1 B ILE 474 ? B ILE 203 
82  1 Y 1 B SER 475 ? B SER 204 
83  1 Y 1 B PRO 476 ? B PRO 205 
84  1 Y 1 B GLU 477 ? B GLU 206 
85  1 Y 1 B PRO 478 ? B PRO 207 
86  1 Y 1 B LYS 479 ? B LYS 208 
87  1 Y 1 B THR 480 ? B THR 209 
88  1 Y 1 B PHE 535 ? B PHE 264 
89  1 Y 1 B ALA 536 ? B ALA 265 
90  1 Y 1 B ALA 537 ? B ALA 266 
91  1 Y 1 B SER 538 ? B SER 267 
92  1 Y 1 B GLY 539 ? B GLY 268 
93  1 Y 1 B LEU 540 ? B LEU 269 
94  1 Y 1 B GLU 541 ? B GLU 270 
95  1 Y 1 B PHE 542 ? B PHE 271 
96  1 Y 1 B ASP 543 ? B ASP 272 
97  1 Y 1 B CYS 544 ? B CYS 273 
98  1 Y 1 B TYR 545 ? B TYR 274 
99  1 Y 1 B GLY 546 ? B GLY 275 
100 1 Y 1 B GLY 547 ? B GLY 276 
101 1 Y 1 B GLY 548 ? B GLY 277 
102 1 Y 1 B LEU 549 ? B LEU 278 
103 1 Y 1 B SER 550 ? B SER 279 
104 1 Y 1 B SER 770 ? B SER 366 
105 1 Y 1 B THR 771 ? B THR 367 
106 1 Y 1 B SER 772 ? B SER 368 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1BWW C5   C  Y N 1   
A1BWW C7   C  Y N 2   
A1BWW C8   C  N N 3   
A1BWW C10  C  N N 4   
A1BWW C15  C  Y N 5   
A1BWW C17  C  Y N 6   
A1BWW C20  C  Y N 7   
A1BWW C21  C  Y N 8   
A1BWW C22  C  Y N 9   
A1BWW C24  C  Y N 10  
A1BWW C26  C  Y N 11  
A1BWW C28  C  Y N 12  
A1BWW C1   C  N N 13  
A1BWW C11  C  Y N 14  
A1BWW C12  C  Y N 15  
A1BWW C14  C  Y N 16  
A1BWW C18  C  Y N 17  
A1BWW C19  C  N N 18  
A1BWW C23  C  Y N 19  
A1BWW C25  C  Y N 20  
A1BWW C29  C  Y N 21  
A1BWW C3   C  Y N 22  
A1BWW C31  C  N N 23  
A1BWW C32  C  N N 24  
A1BWW C36  C  Y N 25  
A1BWW C9   C  N N 26  
A1BWW F33  F  N N 27  
A1BWW F34  F  N N 28  
A1BWW F35  F  N N 29  
A1BWW N13  N  Y N 30  
A1BWW N16  N  Y N 31  
A1BWW N27  N  Y N 32  
A1BWW N30  N  Y N 33  
A1BWW N37  N  Y N 34  
A1BWW N4   N  Y N 35  
A1BWW N6   N  Y N 36  
A1BWW O2   O  N N 37  
A1BWW H41  H  N N 38  
A1BWW H42  H  N N 39  
A1BWW H46  H  N N 40  
A1BWW H45  H  N N 41  
A1BWW H49  H  N N 42  
A1BWW H52  H  N N 43  
A1BWW H53  H  N N 44  
A1BWW H54  H  N N 45  
A1BWW H40  H  N N 46  
A1BWW H39  H  N N 47  
A1BWW H38  H  N N 48  
A1BWW H47  H  N N 49  
A1BWW H51  H  N N 50  
A1BWW H50  H  N N 51  
A1BWW H55  H  N N 52  
A1BWW H56  H  N N 53  
A1BWW H58  H  N N 54  
A1BWW H59  H  N N 55  
A1BWW H57  H  N N 56  
A1BWW H43  H  N N 57  
A1BWW H44  H  N N 58  
A1BWW H48  H  N N 59  
ALA   N    N  N N 60  
ALA   CA   C  N S 61  
ALA   C    C  N N 62  
ALA   O    O  N N 63  
ALA   CB   C  N N 64  
ALA   OXT  O  N N 65  
ALA   H    H  N N 66  
ALA   H2   H  N N 67  
ALA   HA   H  N N 68  
ALA   HB1  H  N N 69  
ALA   HB2  H  N N 70  
ALA   HB3  H  N N 71  
ALA   HXT  H  N N 72  
ARG   N    N  N N 73  
ARG   CA   C  N S 74  
ARG   C    C  N N 75  
ARG   O    O  N N 76  
ARG   CB   C  N N 77  
ARG   CG   C  N N 78  
ARG   CD   C  N N 79  
ARG   NE   N  N N 80  
ARG   CZ   C  N N 81  
ARG   NH1  N  N N 82  
ARG   NH2  N  N N 83  
ARG   OXT  O  N N 84  
ARG   H    H  N N 85  
ARG   H2   H  N N 86  
ARG   HA   H  N N 87  
ARG   HB2  H  N N 88  
ARG   HB3  H  N N 89  
ARG   HG2  H  N N 90  
ARG   HG3  H  N N 91  
ARG   HD2  H  N N 92  
ARG   HD3  H  N N 93  
ARG   HE   H  N N 94  
ARG   HH11 H  N N 95  
ARG   HH12 H  N N 96  
ARG   HH21 H  N N 97  
ARG   HH22 H  N N 98  
ARG   HXT  H  N N 99  
ASN   N    N  N N 100 
ASN   CA   C  N S 101 
ASN   C    C  N N 102 
ASN   O    O  N N 103 
ASN   CB   C  N N 104 
ASN   CG   C  N N 105 
ASN   OD1  O  N N 106 
ASN   ND2  N  N N 107 
ASN   OXT  O  N N 108 
ASN   H    H  N N 109 
ASN   H2   H  N N 110 
ASN   HA   H  N N 111 
ASN   HB2  H  N N 112 
ASN   HB3  H  N N 113 
ASN   HD21 H  N N 114 
ASN   HD22 H  N N 115 
ASN   HXT  H  N N 116 
ASP   N    N  N N 117 
ASP   CA   C  N S 118 
ASP   C    C  N N 119 
ASP   O    O  N N 120 
ASP   CB   C  N N 121 
ASP   CG   C  N N 122 
ASP   OD1  O  N N 123 
ASP   OD2  O  N N 124 
ASP   OXT  O  N N 125 
ASP   H    H  N N 126 
ASP   H2   H  N N 127 
ASP   HA   H  N N 128 
ASP   HB2  H  N N 129 
ASP   HB3  H  N N 130 
ASP   HD2  H  N N 131 
ASP   HXT  H  N N 132 
CYS   N    N  N N 133 
CYS   CA   C  N R 134 
CYS   C    C  N N 135 
CYS   O    O  N N 136 
CYS   CB   C  N N 137 
CYS   SG   S  N N 138 
CYS   OXT  O  N N 139 
CYS   H    H  N N 140 
CYS   H2   H  N N 141 
CYS   HA   H  N N 142 
CYS   HB2  H  N N 143 
CYS   HB3  H  N N 144 
CYS   HG   H  N N 145 
CYS   HXT  H  N N 146 
GLN   N    N  N N 147 
GLN   CA   C  N S 148 
GLN   C    C  N N 149 
GLN   O    O  N N 150 
GLN   CB   C  N N 151 
GLN   CG   C  N N 152 
GLN   CD   C  N N 153 
GLN   OE1  O  N N 154 
GLN   NE2  N  N N 155 
GLN   OXT  O  N N 156 
GLN   H    H  N N 157 
GLN   H2   H  N N 158 
GLN   HA   H  N N 159 
GLN   HB2  H  N N 160 
GLN   HB3  H  N N 161 
GLN   HG2  H  N N 162 
GLN   HG3  H  N N 163 
GLN   HE21 H  N N 164 
GLN   HE22 H  N N 165 
GLN   HXT  H  N N 166 
GLU   N    N  N N 167 
GLU   CA   C  N S 168 
GLU   C    C  N N 169 
GLU   O    O  N N 170 
GLU   CB   C  N N 171 
GLU   CG   C  N N 172 
GLU   CD   C  N N 173 
GLU   OE1  O  N N 174 
GLU   OE2  O  N N 175 
GLU   OXT  O  N N 176 
GLU   H    H  N N 177 
GLU   H2   H  N N 178 
GLU   HA   H  N N 179 
GLU   HB2  H  N N 180 
GLU   HB3  H  N N 181 
GLU   HG2  H  N N 182 
GLU   HG3  H  N N 183 
GLU   HE2  H  N N 184 
GLU   HXT  H  N N 185 
GLY   N    N  N N 186 
GLY   CA   C  N N 187 
GLY   C    C  N N 188 
GLY   O    O  N N 189 
GLY   OXT  O  N N 190 
GLY   H    H  N N 191 
GLY   H2   H  N N 192 
GLY   HA2  H  N N 193 
GLY   HA3  H  N N 194 
GLY   HXT  H  N N 195 
HIS   N    N  N N 196 
HIS   CA   C  N S 197 
HIS   C    C  N N 198 
HIS   O    O  N N 199 
HIS   CB   C  N N 200 
HIS   CG   C  Y N 201 
HIS   ND1  N  Y N 202 
HIS   CD2  C  Y N 203 
HIS   CE1  C  Y N 204 
HIS   NE2  N  Y N 205 
HIS   OXT  O  N N 206 
HIS   H    H  N N 207 
HIS   H2   H  N N 208 
HIS   HA   H  N N 209 
HIS   HB2  H  N N 210 
HIS   HB3  H  N N 211 
HIS   HD1  H  N N 212 
HIS   HD2  H  N N 213 
HIS   HE1  H  N N 214 
HIS   HE2  H  N N 215 
HIS   HXT  H  N N 216 
HOH   O    O  N N 217 
HOH   H1   H  N N 218 
HOH   H2   H  N N 219 
ILE   N    N  N N 220 
ILE   CA   C  N S 221 
ILE   C    C  N N 222 
ILE   O    O  N N 223 
ILE   CB   C  N S 224 
ILE   CG1  C  N N 225 
ILE   CG2  C  N N 226 
ILE   CD1  C  N N 227 
ILE   OXT  O  N N 228 
ILE   H    H  N N 229 
ILE   H2   H  N N 230 
ILE   HA   H  N N 231 
ILE   HB   H  N N 232 
ILE   HG12 H  N N 233 
ILE   HG13 H  N N 234 
ILE   HG21 H  N N 235 
ILE   HG22 H  N N 236 
ILE   HG23 H  N N 237 
ILE   HD11 H  N N 238 
ILE   HD12 H  N N 239 
ILE   HD13 H  N N 240 
ILE   HXT  H  N N 241 
LEU   N    N  N N 242 
LEU   CA   C  N S 243 
LEU   C    C  N N 244 
LEU   O    O  N N 245 
LEU   CB   C  N N 246 
LEU   CG   C  N N 247 
LEU   CD1  C  N N 248 
LEU   CD2  C  N N 249 
LEU   OXT  O  N N 250 
LEU   H    H  N N 251 
LEU   H2   H  N N 252 
LEU   HA   H  N N 253 
LEU   HB2  H  N N 254 
LEU   HB3  H  N N 255 
LEU   HG   H  N N 256 
LEU   HD11 H  N N 257 
LEU   HD12 H  N N 258 
LEU   HD13 H  N N 259 
LEU   HD21 H  N N 260 
LEU   HD22 H  N N 261 
LEU   HD23 H  N N 262 
LEU   HXT  H  N N 263 
LYS   N    N  N N 264 
LYS   CA   C  N S 265 
LYS   C    C  N N 266 
LYS   O    O  N N 267 
LYS   CB   C  N N 268 
LYS   CG   C  N N 269 
LYS   CD   C  N N 270 
LYS   CE   C  N N 271 
LYS   NZ   N  N N 272 
LYS   OXT  O  N N 273 
LYS   H    H  N N 274 
LYS   H2   H  N N 275 
LYS   HA   H  N N 276 
LYS   HB2  H  N N 277 
LYS   HB3  H  N N 278 
LYS   HG2  H  N N 279 
LYS   HG3  H  N N 280 
LYS   HD2  H  N N 281 
LYS   HD3  H  N N 282 
LYS   HE2  H  N N 283 
LYS   HE3  H  N N 284 
LYS   HZ1  H  N N 285 
LYS   HZ2  H  N N 286 
LYS   HZ3  H  N N 287 
LYS   HXT  H  N N 288 
MET   N    N  N N 289 
MET   CA   C  N S 290 
MET   C    C  N N 291 
MET   O    O  N N 292 
MET   CB   C  N N 293 
MET   CG   C  N N 294 
MET   SD   S  N N 295 
MET   CE   C  N N 296 
MET   OXT  O  N N 297 
MET   H    H  N N 298 
MET   H2   H  N N 299 
MET   HA   H  N N 300 
MET   HB2  H  N N 301 
MET   HB3  H  N N 302 
MET   HG2  H  N N 303 
MET   HG3  H  N N 304 
MET   HE1  H  N N 305 
MET   HE2  H  N N 306 
MET   HE3  H  N N 307 
MET   HXT  H  N N 308 
PHE   N    N  N N 309 
PHE   CA   C  N S 310 
PHE   C    C  N N 311 
PHE   O    O  N N 312 
PHE   CB   C  N N 313 
PHE   CG   C  Y N 314 
PHE   CD1  C  Y N 315 
PHE   CD2  C  Y N 316 
PHE   CE1  C  Y N 317 
PHE   CE2  C  Y N 318 
PHE   CZ   C  Y N 319 
PHE   OXT  O  N N 320 
PHE   H    H  N N 321 
PHE   H2   H  N N 322 
PHE   HA   H  N N 323 
PHE   HB2  H  N N 324 
PHE   HB3  H  N N 325 
PHE   HD1  H  N N 326 
PHE   HD2  H  N N 327 
PHE   HE1  H  N N 328 
PHE   HE2  H  N N 329 
PHE   HZ   H  N N 330 
PHE   HXT  H  N N 331 
PRO   N    N  N N 332 
PRO   CA   C  N S 333 
PRO   C    C  N N 334 
PRO   O    O  N N 335 
PRO   CB   C  N N 336 
PRO   CG   C  N N 337 
PRO   CD   C  N N 338 
PRO   OXT  O  N N 339 
PRO   H    H  N N 340 
PRO   HA   H  N N 341 
PRO   HB2  H  N N 342 
PRO   HB3  H  N N 343 
PRO   HG2  H  N N 344 
PRO   HG3  H  N N 345 
PRO   HD2  H  N N 346 
PRO   HD3  H  N N 347 
PRO   HXT  H  N N 348 
SER   N    N  N N 349 
SER   CA   C  N S 350 
SER   C    C  N N 351 
SER   O    O  N N 352 
SER   CB   C  N N 353 
SER   OG   O  N N 354 
SER   OXT  O  N N 355 
SER   H    H  N N 356 
SER   H2   H  N N 357 
SER   HA   H  N N 358 
SER   HB2  H  N N 359 
SER   HB3  H  N N 360 
SER   HG   H  N N 361 
SER   HXT  H  N N 362 
THR   N    N  N N 363 
THR   CA   C  N S 364 
THR   C    C  N N 365 
THR   O    O  N N 366 
THR   CB   C  N R 367 
THR   OG1  O  N N 368 
THR   CG2  C  N N 369 
THR   OXT  O  N N 370 
THR   H    H  N N 371 
THR   H2   H  N N 372 
THR   HA   H  N N 373 
THR   HB   H  N N 374 
THR   HG1  H  N N 375 
THR   HG21 H  N N 376 
THR   HG22 H  N N 377 
THR   HG23 H  N N 378 
THR   HXT  H  N N 379 
TRP   N    N  N N 380 
TRP   CA   C  N S 381 
TRP   C    C  N N 382 
TRP   O    O  N N 383 
TRP   CB   C  N N 384 
TRP   CG   C  Y N 385 
TRP   CD1  C  Y N 386 
TRP   CD2  C  Y N 387 
TRP   NE1  N  Y N 388 
TRP   CE2  C  Y N 389 
TRP   CE3  C  Y N 390 
TRP   CZ2  C  Y N 391 
TRP   CZ3  C  Y N 392 
TRP   CH2  C  Y N 393 
TRP   OXT  O  N N 394 
TRP   H    H  N N 395 
TRP   H2   H  N N 396 
TRP   HA   H  N N 397 
TRP   HB2  H  N N 398 
TRP   HB3  H  N N 399 
TRP   HD1  H  N N 400 
TRP   HE1  H  N N 401 
TRP   HE3  H  N N 402 
TRP   HZ2  H  N N 403 
TRP   HZ3  H  N N 404 
TRP   HH2  H  N N 405 
TRP   HXT  H  N N 406 
TYR   N    N  N N 407 
TYR   CA   C  N S 408 
TYR   C    C  N N 409 
TYR   O    O  N N 410 
TYR   CB   C  N N 411 
TYR   CG   C  Y N 412 
TYR   CD1  C  Y N 413 
TYR   CD2  C  Y N 414 
TYR   CE1  C  Y N 415 
TYR   CE2  C  Y N 416 
TYR   CZ   C  Y N 417 
TYR   OH   O  N N 418 
TYR   OXT  O  N N 419 
TYR   H    H  N N 420 
TYR   H2   H  N N 421 
TYR   HA   H  N N 422 
TYR   HB2  H  N N 423 
TYR   HB3  H  N N 424 
TYR   HD1  H  N N 425 
TYR   HD2  H  N N 426 
TYR   HE1  H  N N 427 
TYR   HE2  H  N N 428 
TYR   HH   H  N N 429 
TYR   HXT  H  N N 430 
VAL   N    N  N N 431 
VAL   CA   C  N S 432 
VAL   C    C  N N 433 
VAL   O    O  N N 434 
VAL   CB   C  N N 435 
VAL   CG1  C  N N 436 
VAL   CG2  C  N N 437 
VAL   OXT  O  N N 438 
VAL   H    H  N N 439 
VAL   H2   H  N N 440 
VAL   HA   H  N N 441 
VAL   HB   H  N N 442 
VAL   HG11 H  N N 443 
VAL   HG12 H  N N 444 
VAL   HG13 H  N N 445 
VAL   HG21 H  N N 446 
VAL   HG22 H  N N 447 
VAL   HG23 H  N N 448 
VAL   HXT  H  N N 449 
ZN    ZN   ZN N N 450 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1BWW C1  O2   sing N N 1   
A1BWW O2  C3   sing N N 2   
A1BWW C3  N4   doub Y N 3   
A1BWW C3  C11  sing Y N 4   
A1BWW N4  C5   sing Y N 5   
A1BWW C5  N6   doub Y N 6   
A1BWW N6  C7   sing Y N 7   
A1BWW C7  C8   sing N N 8   
A1BWW C7  C11  doub Y N 9   
A1BWW C8  C9   sing N N 10  
A1BWW C8  C10  sing N N 11  
A1BWW C9  C10  sing N N 12  
A1BWW C11 C12  sing N N 13  
A1BWW C12 N13  sing Y N 14  
A1BWW C12 N37  doub Y N 15  
A1BWW N13 C14  doub Y N 16  
A1BWW C14 C15  sing Y N 17  
A1BWW C15 N16  sing Y N 18  
A1BWW C15 C36  doub Y N 19  
A1BWW N16 C17  sing Y N 20  
A1BWW C17 C18  doub Y N 21  
A1BWW C18 C19  sing N N 22  
A1BWW C18 C36  sing Y N 23  
A1BWW C19 C20  sing N N 24  
A1BWW C20 C21  doub Y N 25  
A1BWW C20 C25  sing Y N 26  
A1BWW C21 C22  sing Y N 27  
A1BWW C22 C23  doub Y N 28  
A1BWW C23 C24  sing Y N 29  
A1BWW C23 C26  sing N N 30  
A1BWW C24 C25  doub Y N 31  
A1BWW C26 N27  doub Y N 32  
A1BWW C26 N30  sing Y N 33  
A1BWW N27 C28  sing Y N 34  
A1BWW C28 C29  doub Y N 35  
A1BWW C28 C32  sing N N 36  
A1BWW C29 N30  sing Y N 37  
A1BWW N30 C31  sing N N 38  
A1BWW C32 F33  sing N N 39  
A1BWW C32 F34  sing N N 40  
A1BWW C32 F35  sing N N 41  
A1BWW C36 N37  sing Y N 42  
A1BWW C5  H41  sing N N 43  
A1BWW C8  H42  sing N N 44  
A1BWW C10 H46  sing N N 45  
A1BWW C10 H45  sing N N 46  
A1BWW C17 H49  sing N N 47  
A1BWW C21 H52  sing N N 48  
A1BWW C22 H53  sing N N 49  
A1BWW C24 H54  sing N N 50  
A1BWW C1  H40  sing N N 51  
A1BWW C1  H39  sing N N 52  
A1BWW C1  H38  sing N N 53  
A1BWW C14 H47  sing N N 54  
A1BWW C19 H51  sing N N 55  
A1BWW C19 H50  sing N N 56  
A1BWW C25 H55  sing N N 57  
A1BWW C29 H56  sing N N 58  
A1BWW C31 H58  sing N N 59  
A1BWW C31 H59  sing N N 60  
A1BWW C31 H57  sing N N 61  
A1BWW C9  H43  sing N N 62  
A1BWW C9  H44  sing N N 63  
A1BWW N16 H48  sing N N 64  
ALA   N   CA   sing N N 65  
ALA   N   H    sing N N 66  
ALA   N   H2   sing N N 67  
ALA   CA  C    sing N N 68  
ALA   CA  CB   sing N N 69  
ALA   CA  HA   sing N N 70  
ALA   C   O    doub N N 71  
ALA   C   OXT  sing N N 72  
ALA   CB  HB1  sing N N 73  
ALA   CB  HB2  sing N N 74  
ALA   CB  HB3  sing N N 75  
ALA   OXT HXT  sing N N 76  
ARG   N   CA   sing N N 77  
ARG   N   H    sing N N 78  
ARG   N   H2   sing N N 79  
ARG   CA  C    sing N N 80  
ARG   CA  CB   sing N N 81  
ARG   CA  HA   sing N N 82  
ARG   C   O    doub N N 83  
ARG   C   OXT  sing N N 84  
ARG   CB  CG   sing N N 85  
ARG   CB  HB2  sing N N 86  
ARG   CB  HB3  sing N N 87  
ARG   CG  CD   sing N N 88  
ARG   CG  HG2  sing N N 89  
ARG   CG  HG3  sing N N 90  
ARG   CD  NE   sing N N 91  
ARG   CD  HD2  sing N N 92  
ARG   CD  HD3  sing N N 93  
ARG   NE  CZ   sing N N 94  
ARG   NE  HE   sing N N 95  
ARG   CZ  NH1  sing N N 96  
ARG   CZ  NH2  doub N N 97  
ARG   NH1 HH11 sing N N 98  
ARG   NH1 HH12 sing N N 99  
ARG   NH2 HH21 sing N N 100 
ARG   NH2 HH22 sing N N 101 
ARG   OXT HXT  sing N N 102 
ASN   N   CA   sing N N 103 
ASN   N   H    sing N N 104 
ASN   N   H2   sing N N 105 
ASN   CA  C    sing N N 106 
ASN   CA  CB   sing N N 107 
ASN   CA  HA   sing N N 108 
ASN   C   O    doub N N 109 
ASN   C   OXT  sing N N 110 
ASN   CB  CG   sing N N 111 
ASN   CB  HB2  sing N N 112 
ASN   CB  HB3  sing N N 113 
ASN   CG  OD1  doub N N 114 
ASN   CG  ND2  sing N N 115 
ASN   ND2 HD21 sing N N 116 
ASN   ND2 HD22 sing N N 117 
ASN   OXT HXT  sing N N 118 
ASP   N   CA   sing N N 119 
ASP   N   H    sing N N 120 
ASP   N   H2   sing N N 121 
ASP   CA  C    sing N N 122 
ASP   CA  CB   sing N N 123 
ASP   CA  HA   sing N N 124 
ASP   C   O    doub N N 125 
ASP   C   OXT  sing N N 126 
ASP   CB  CG   sing N N 127 
ASP   CB  HB2  sing N N 128 
ASP   CB  HB3  sing N N 129 
ASP   CG  OD1  doub N N 130 
ASP   CG  OD2  sing N N 131 
ASP   OD2 HD2  sing N N 132 
ASP   OXT HXT  sing N N 133 
CYS   N   CA   sing N N 134 
CYS   N   H    sing N N 135 
CYS   N   H2   sing N N 136 
CYS   CA  C    sing N N 137 
CYS   CA  CB   sing N N 138 
CYS   CA  HA   sing N N 139 
CYS   C   O    doub N N 140 
CYS   C   OXT  sing N N 141 
CYS   CB  SG   sing N N 142 
CYS   CB  HB2  sing N N 143 
CYS   CB  HB3  sing N N 144 
CYS   SG  HG   sing N N 145 
CYS   OXT HXT  sing N N 146 
GLN   N   CA   sing N N 147 
GLN   N   H    sing N N 148 
GLN   N   H2   sing N N 149 
GLN   CA  C    sing N N 150 
GLN   CA  CB   sing N N 151 
GLN   CA  HA   sing N N 152 
GLN   C   O    doub N N 153 
GLN   C   OXT  sing N N 154 
GLN   CB  CG   sing N N 155 
GLN   CB  HB2  sing N N 156 
GLN   CB  HB3  sing N N 157 
GLN   CG  CD   sing N N 158 
GLN   CG  HG2  sing N N 159 
GLN   CG  HG3  sing N N 160 
GLN   CD  OE1  doub N N 161 
GLN   CD  NE2  sing N N 162 
GLN   NE2 HE21 sing N N 163 
GLN   NE2 HE22 sing N N 164 
GLN   OXT HXT  sing N N 165 
GLU   N   CA   sing N N 166 
GLU   N   H    sing N N 167 
GLU   N   H2   sing N N 168 
GLU   CA  C    sing N N 169 
GLU   CA  CB   sing N N 170 
GLU   CA  HA   sing N N 171 
GLU   C   O    doub N N 172 
GLU   C   OXT  sing N N 173 
GLU   CB  CG   sing N N 174 
GLU   CB  HB2  sing N N 175 
GLU   CB  HB3  sing N N 176 
GLU   CG  CD   sing N N 177 
GLU   CG  HG2  sing N N 178 
GLU   CG  HG3  sing N N 179 
GLU   CD  OE1  doub N N 180 
GLU   CD  OE2  sing N N 181 
GLU   OE2 HE2  sing N N 182 
GLU   OXT HXT  sing N N 183 
GLY   N   CA   sing N N 184 
GLY   N   H    sing N N 185 
GLY   N   H2   sing N N 186 
GLY   CA  C    sing N N 187 
GLY   CA  HA2  sing N N 188 
GLY   CA  HA3  sing N N 189 
GLY   C   O    doub N N 190 
GLY   C   OXT  sing N N 191 
GLY   OXT HXT  sing N N 192 
HIS   N   CA   sing N N 193 
HIS   N   H    sing N N 194 
HIS   N   H2   sing N N 195 
HIS   CA  C    sing N N 196 
HIS   CA  CB   sing N N 197 
HIS   CA  HA   sing N N 198 
HIS   C   O    doub N N 199 
HIS   C   OXT  sing N N 200 
HIS   CB  CG   sing N N 201 
HIS   CB  HB2  sing N N 202 
HIS   CB  HB3  sing N N 203 
HIS   CG  ND1  sing Y N 204 
HIS   CG  CD2  doub Y N 205 
HIS   ND1 CE1  doub Y N 206 
HIS   ND1 HD1  sing N N 207 
HIS   CD2 NE2  sing Y N 208 
HIS   CD2 HD2  sing N N 209 
HIS   CE1 NE2  sing Y N 210 
HIS   CE1 HE1  sing N N 211 
HIS   NE2 HE2  sing N N 212 
HIS   OXT HXT  sing N N 213 
HOH   O   H1   sing N N 214 
HOH   O   H2   sing N N 215 
ILE   N   CA   sing N N 216 
ILE   N   H    sing N N 217 
ILE   N   H2   sing N N 218 
ILE   CA  C    sing N N 219 
ILE   CA  CB   sing N N 220 
ILE   CA  HA   sing N N 221 
ILE   C   O    doub N N 222 
ILE   C   OXT  sing N N 223 
ILE   CB  CG1  sing N N 224 
ILE   CB  CG2  sing N N 225 
ILE   CB  HB   sing N N 226 
ILE   CG1 CD1  sing N N 227 
ILE   CG1 HG12 sing N N 228 
ILE   CG1 HG13 sing N N 229 
ILE   CG2 HG21 sing N N 230 
ILE   CG2 HG22 sing N N 231 
ILE   CG2 HG23 sing N N 232 
ILE   CD1 HD11 sing N N 233 
ILE   CD1 HD12 sing N N 234 
ILE   CD1 HD13 sing N N 235 
ILE   OXT HXT  sing N N 236 
LEU   N   CA   sing N N 237 
LEU   N   H    sing N N 238 
LEU   N   H2   sing N N 239 
LEU   CA  C    sing N N 240 
LEU   CA  CB   sing N N 241 
LEU   CA  HA   sing N N 242 
LEU   C   O    doub N N 243 
LEU   C   OXT  sing N N 244 
LEU   CB  CG   sing N N 245 
LEU   CB  HB2  sing N N 246 
LEU   CB  HB3  sing N N 247 
LEU   CG  CD1  sing N N 248 
LEU   CG  CD2  sing N N 249 
LEU   CG  HG   sing N N 250 
LEU   CD1 HD11 sing N N 251 
LEU   CD1 HD12 sing N N 252 
LEU   CD1 HD13 sing N N 253 
LEU   CD2 HD21 sing N N 254 
LEU   CD2 HD22 sing N N 255 
LEU   CD2 HD23 sing N N 256 
LEU   OXT HXT  sing N N 257 
LYS   N   CA   sing N N 258 
LYS   N   H    sing N N 259 
LYS   N   H2   sing N N 260 
LYS   CA  C    sing N N 261 
LYS   CA  CB   sing N N 262 
LYS   CA  HA   sing N N 263 
LYS   C   O    doub N N 264 
LYS   C   OXT  sing N N 265 
LYS   CB  CG   sing N N 266 
LYS   CB  HB2  sing N N 267 
LYS   CB  HB3  sing N N 268 
LYS   CG  CD   sing N N 269 
LYS   CG  HG2  sing N N 270 
LYS   CG  HG3  sing N N 271 
LYS   CD  CE   sing N N 272 
LYS   CD  HD2  sing N N 273 
LYS   CD  HD3  sing N N 274 
LYS   CE  NZ   sing N N 275 
LYS   CE  HE2  sing N N 276 
LYS   CE  HE3  sing N N 277 
LYS   NZ  HZ1  sing N N 278 
LYS   NZ  HZ2  sing N N 279 
LYS   NZ  HZ3  sing N N 280 
LYS   OXT HXT  sing N N 281 
MET   N   CA   sing N N 282 
MET   N   H    sing N N 283 
MET   N   H2   sing N N 284 
MET   CA  C    sing N N 285 
MET   CA  CB   sing N N 286 
MET   CA  HA   sing N N 287 
MET   C   O    doub N N 288 
MET   C   OXT  sing N N 289 
MET   CB  CG   sing N N 290 
MET   CB  HB2  sing N N 291 
MET   CB  HB3  sing N N 292 
MET   CG  SD   sing N N 293 
MET   CG  HG2  sing N N 294 
MET   CG  HG3  sing N N 295 
MET   SD  CE   sing N N 296 
MET   CE  HE1  sing N N 297 
MET   CE  HE2  sing N N 298 
MET   CE  HE3  sing N N 299 
MET   OXT HXT  sing N N 300 
PHE   N   CA   sing N N 301 
PHE   N   H    sing N N 302 
PHE   N   H2   sing N N 303 
PHE   CA  C    sing N N 304 
PHE   CA  CB   sing N N 305 
PHE   CA  HA   sing N N 306 
PHE   C   O    doub N N 307 
PHE   C   OXT  sing N N 308 
PHE   CB  CG   sing N N 309 
PHE   CB  HB2  sing N N 310 
PHE   CB  HB3  sing N N 311 
PHE   CG  CD1  doub Y N 312 
PHE   CG  CD2  sing Y N 313 
PHE   CD1 CE1  sing Y N 314 
PHE   CD1 HD1  sing N N 315 
PHE   CD2 CE2  doub Y N 316 
PHE   CD2 HD2  sing N N 317 
PHE   CE1 CZ   doub Y N 318 
PHE   CE1 HE1  sing N N 319 
PHE   CE2 CZ   sing Y N 320 
PHE   CE2 HE2  sing N N 321 
PHE   CZ  HZ   sing N N 322 
PHE   OXT HXT  sing N N 323 
PRO   N   CA   sing N N 324 
PRO   N   CD   sing N N 325 
PRO   N   H    sing N N 326 
PRO   CA  C    sing N N 327 
PRO   CA  CB   sing N N 328 
PRO   CA  HA   sing N N 329 
PRO   C   O    doub N N 330 
PRO   C   OXT  sing N N 331 
PRO   CB  CG   sing N N 332 
PRO   CB  HB2  sing N N 333 
PRO   CB  HB3  sing N N 334 
PRO   CG  CD   sing N N 335 
PRO   CG  HG2  sing N N 336 
PRO   CG  HG3  sing N N 337 
PRO   CD  HD2  sing N N 338 
PRO   CD  HD3  sing N N 339 
PRO   OXT HXT  sing N N 340 
SER   N   CA   sing N N 341 
SER   N   H    sing N N 342 
SER   N   H2   sing N N 343 
SER   CA  C    sing N N 344 
SER   CA  CB   sing N N 345 
SER   CA  HA   sing N N 346 
SER   C   O    doub N N 347 
SER   C   OXT  sing N N 348 
SER   CB  OG   sing N N 349 
SER   CB  HB2  sing N N 350 
SER   CB  HB3  sing N N 351 
SER   OG  HG   sing N N 352 
SER   OXT HXT  sing N N 353 
THR   N   CA   sing N N 354 
THR   N   H    sing N N 355 
THR   N   H2   sing N N 356 
THR   CA  C    sing N N 357 
THR   CA  CB   sing N N 358 
THR   CA  HA   sing N N 359 
THR   C   O    doub N N 360 
THR   C   OXT  sing N N 361 
THR   CB  OG1  sing N N 362 
THR   CB  CG2  sing N N 363 
THR   CB  HB   sing N N 364 
THR   OG1 HG1  sing N N 365 
THR   CG2 HG21 sing N N 366 
THR   CG2 HG22 sing N N 367 
THR   CG2 HG23 sing N N 368 
THR   OXT HXT  sing N N 369 
TRP   N   CA   sing N N 370 
TRP   N   H    sing N N 371 
TRP   N   H2   sing N N 372 
TRP   CA  C    sing N N 373 
TRP   CA  CB   sing N N 374 
TRP   CA  HA   sing N N 375 
TRP   C   O    doub N N 376 
TRP   C   OXT  sing N N 377 
TRP   CB  CG   sing N N 378 
TRP   CB  HB2  sing N N 379 
TRP   CB  HB3  sing N N 380 
TRP   CG  CD1  doub Y N 381 
TRP   CG  CD2  sing Y N 382 
TRP   CD1 NE1  sing Y N 383 
TRP   CD1 HD1  sing N N 384 
TRP   CD2 CE2  doub Y N 385 
TRP   CD2 CE3  sing Y N 386 
TRP   NE1 CE2  sing Y N 387 
TRP   NE1 HE1  sing N N 388 
TRP   CE2 CZ2  sing Y N 389 
TRP   CE3 CZ3  doub Y N 390 
TRP   CE3 HE3  sing N N 391 
TRP   CZ2 CH2  doub Y N 392 
TRP   CZ2 HZ2  sing N N 393 
TRP   CZ3 CH2  sing Y N 394 
TRP   CZ3 HZ3  sing N N 395 
TRP   CH2 HH2  sing N N 396 
TRP   OXT HXT  sing N N 397 
TYR   N   CA   sing N N 398 
TYR   N   H    sing N N 399 
TYR   N   H2   sing N N 400 
TYR   CA  C    sing N N 401 
TYR   CA  CB   sing N N 402 
TYR   CA  HA   sing N N 403 
TYR   C   O    doub N N 404 
TYR   C   OXT  sing N N 405 
TYR   CB  CG   sing N N 406 
TYR   CB  HB2  sing N N 407 
TYR   CB  HB3  sing N N 408 
TYR   CG  CD1  doub Y N 409 
TYR   CG  CD2  sing Y N 410 
TYR   CD1 CE1  sing Y N 411 
TYR   CD1 HD1  sing N N 412 
TYR   CD2 CE2  doub Y N 413 
TYR   CD2 HD2  sing N N 414 
TYR   CE1 CZ   doub Y N 415 
TYR   CE1 HE1  sing N N 416 
TYR   CE2 CZ   sing Y N 417 
TYR   CE2 HE2  sing N N 418 
TYR   CZ  OH   sing N N 419 
TYR   OH  HH   sing N N 420 
TYR   OXT HXT  sing N N 421 
VAL   N   CA   sing N N 422 
VAL   N   H    sing N N 423 
VAL   N   H2   sing N N 424 
VAL   CA  C    sing N N 425 
VAL   CA  CB   sing N N 426 
VAL   CA  HA   sing N N 427 
VAL   C   O    doub N N 428 
VAL   C   OXT  sing N N 429 
VAL   CB  CG1  sing N N 430 
VAL   CB  CG2  sing N N 431 
VAL   CB  HB   sing N N 432 
VAL   CG1 HG11 sing N N 433 
VAL   CG1 HG12 sing N N 434 
VAL   CG1 HG13 sing N N 435 
VAL   CG2 HG21 sing N N 436 
VAL   CG2 HG22 sing N N 437 
VAL   CG2 HG23 sing N N 438 
VAL   OXT HXT  sing N N 439 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7AY2 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'I 2 2 2' 
_space_group.name_Hall        'I 2 2' 
_space_group.IT_number        23 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9N9Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.008117 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006177 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006231 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F  ? ? 8.95735  ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 6.96715  ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
ZN ? ? 29.81721 ?       ? ? 5.87945  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ARG   A 1 13  ? 51.23253 -7.07494  49.19326  1.000 86.18545  ? 13  ARG   A N   1 
ATOM   2    C  CA  . ARG   A 1 13  ? 51.64597 -8.20553  50.01600  1.000 92.19837  ? 13  ARG   A CA  1 
ATOM   3    C  C   . ARG   A 1 13  ? 50.54404 -9.25763  50.10193  1.000 98.16875  ? 13  ARG   A C   1 
ATOM   4    O  O   . ARG   A 1 13  ? 50.68277 -10.35723 49.56568  1.000 99.83198  ? 13  ARG   A O   1 
ATOM   5    C  CB  . ARG   A 1 13  ? 52.03863 -7.73222  51.41742  1.000 91.44899  ? 13  ARG   A CB  1 
ATOM   6    C  CG  . ARG   A 1 13  ? 53.30761 -6.89490  51.45197  1.000 90.15168  ? 13  ARG   A CG  1 
ATOM   7    C  CD  . ARG   A 1 13  ? 53.58067 -6.35016  52.84463  1.000 97.07992  ? 13  ARG   A CD  1 
ATOM   8    N  NE  . ARG   A 1 13  ? 54.83918 -5.61596  52.90320  1.000 113.97524 ? 13  ARG   A NE  1 
ATOM   9    C  CZ  . ARG   A 1 13  ? 55.26447 -4.93928  53.96136  1.000 112.44571 ? 13  ARG   A CZ  1 
ATOM   10   N  NH1 . ARG   A 1 13  ? 54.54865 -4.87113  55.07185  1.000 110.49196 ? 13  ARG   A NH1 1 
ATOM   11   N  NH2 . ARG   A 1 13  ? 56.43662 -4.31331  53.90313  1.000 109.55841 ? 13  ARG   A NH2 1 
ATOM   12   N  N   . LYS   A 1 14  ? 49.44966 -8.91531  50.77778  1.000 95.69291  ? 14  LYS   A N   1 
ATOM   13   C  CA  . LYS   A 1 14  ? 48.33291 -9.84099  50.92345  1.000 94.76594  ? 14  LYS   A CA  1 
ATOM   14   C  C   . LYS   A 1 14  ? 47.59657 -9.97204  49.59490  1.000 94.61179  ? 14  LYS   A C   1 
ATOM   15   O  O   . LYS   A 1 14  ? 47.12029 -8.97612  49.03999  1.000 99.87522  ? 14  LYS   A O   1 
ATOM   16   C  CB  . LYS   A 1 14  ? 47.38643 -9.35957  52.02028  1.000 95.20037  ? 14  LYS   A CB  1 
ATOM   17   C  CG  . LYS   A 1 14  ? 46.38455 -10.40738 52.47903  1.000 94.93604  ? 14  LYS   A CG  1 
ATOM   18   C  CD  . LYS   A 1 14  ? 45.31705 -9.80134  53.37778  1.000 98.70815  ? 14  LYS   A CD  1 
ATOM   19   C  CE  . LYS   A 1 14  ? 45.92187 -9.14241  54.60683  1.000 95.73746  ? 14  LYS   A CE  1 
ATOM   20   N  NZ  . LYS   A 1 14  ? 44.87417 -8.52908  55.47105  1.000 65.40174  ? 14  LYS   A NZ  1 
ATOM   21   N  N   . VAL   A 1 15  ? 47.50246 -11.19857 49.08621  1.000 90.04489  ? 15  VAL   A N   1 
ATOM   22   C  CA  . VAL   A 1 15  ? 46.89134 -11.47566 47.79053  1.000 86.80561  ? 15  VAL   A CA  1 
ATOM   23   C  C   . VAL   A 1 15  ? 45.50072 -12.05276 48.00818  1.000 84.36991  ? 15  VAL   A C   1 
ATOM   24   O  O   . VAL   A 1 15  ? 45.29447 -12.89760 48.88940  1.000 79.78435  ? 15  VAL   A O   1 
ATOM   25   C  CB  . VAL   A 1 15  ? 47.76654 -12.43546 46.96055  1.000 79.11745  ? 15  VAL   A CB  1 
ATOM   26   C  CG1 . VAL   A 1 15  ? 47.12684 -12.71506 45.60760  1.000 71.09797  ? 15  VAL   A CG1 1 
ATOM   27   C  CG2 . VAL   A 1 15  ? 49.16249 -11.85909 46.78487  1.000 78.76009  ? 15  VAL   A CG2 1 
ATOM   28   N  N   . GLN   A 1 16  ? 44.54251 -11.59531 47.20507  1.000 79.91567  ? 16  GLN   A N   1 
ATOM   29   C  CA  . GLN   A 1 16  ? 43.17248 -12.07400 47.23363  1.000 75.12012  ? 16  GLN   A CA  1 
ATOM   30   C  C   . GLN   A 1 16  ? 42.80833 -12.64115 45.86849  1.000 72.56424  ? 16  GLN   A C   1 
ATOM   31   O  O   . GLN   A 1 16  ? 43.30695 -12.18552 44.82879  1.000 73.69160  ? 16  GLN   A O   1 
ATOM   32   C  CB  . GLN   A 1 16  ? 42.19937 -10.94938 47.61008  1.000 72.77929  ? 16  GLN   A CB  1 
ATOM   33   C  CG  . GLN   A 1 16  ? 42.46122 -10.32752 48.97289  1.000 77.70995  ? 16  GLN   A CG  1 
ATOM   34   C  CD  . GLN   A 1 16  ? 41.75410 -8.99741  49.15135  1.000 80.20090  ? 16  GLN   A CD  1 
ATOM   35   O  OE1 . GLN   A 1 16  ? 41.68151 -8.19091  48.22383  1.000 80.72114  ? 16  GLN   A OE1 1 
ATOM   36   N  NE2 . GLN   A 1 16  ? 41.22562 -8.76297  50.34716  1.000 77.81462  ? 16  GLN   A NE2 1 
ATOM   37   N  N   . VAL   A 1 17  ? 41.93459 -13.64357 45.88248  1.000 64.90036  ? 17  VAL   A N   1 
ATOM   38   C  CA  . VAL   A 1 17  ? 41.50066 -14.33090 44.67096  1.000 60.29596  ? 17  VAL   A CA  1 
ATOM   39   C  C   . VAL   A 1 17  ? 40.05310 -13.94021 44.41311  1.000 59.63062  ? 17  VAL   A C   1 
ATOM   40   O  O   . VAL   A 1 17  ? 39.16048 -14.27445 45.19947  1.000 61.44918  ? 17  VAL   A O   1 
ATOM   41   C  CB  . VAL   A 1 17  ? 41.65378 -15.85282 44.78948  1.000 56.73942  ? 17  VAL   A CB  1 
ATOM   42   C  CG1 . VAL   A 1 17  ? 41.11858 -16.53651 43.54107  1.000 50.05302  ? 17  VAL   A CG1 1 
ATOM   43   C  CG2 . VAL   A 1 17  ? 43.11101 -16.22043 45.02015  1.000 68.71277  ? 17  VAL   A CG2 1 
ATOM   44   N  N   . SER   A 1 18  ? 39.81482 -13.22376 43.32288  1.000 57.80887  ? 18  SER   A N   1 
ATOM   45   C  CA  . SER   A 1 18  ? 38.48114 -12.77922 42.95701  1.000 54.35994  ? 18  SER   A CA  1 
ATOM   46   C  C   . SER   A 1 18  ? 38.02649 -13.48583 41.68725  1.000 57.69145  ? 18  SER   A C   1 
ATOM   47   O  O   . SER   A 1 18  ? 38.81560 -14.09526 40.96389  1.000 58.80929  ? 18  SER   A O   1 
ATOM   48   C  CB  . SER   A 1 18  ? 38.45061 -11.25904 42.76137  1.000 56.64539  ? 18  SER   A CB  1 
ATOM   49   O  OG  . SER   A 1 18  ? 38.97141 -10.58821 43.89512  1.000 62.01656  ? 18  SER   A OG  1 
ATOM   50   N  N   . TYR   A 1 19  ? 36.72723 -13.39853 41.42671  1.000 59.13988  ? 19  TYR   A N   1 
ATOM   51   C  CA  . TYR   A 1 19  ? 36.18252 -13.89224 40.17003  1.000 64.05465  ? 19  TYR   A CA  1 
ATOM   52   C  C   . TYR   A 1 19  ? 34.85257 -13.20526 39.90418  1.000 67.86448  ? 19  TYR   A C   1 
ATOM   53   O  O   . TYR   A 1 19  ? 34.09636 -12.89943 40.83037  1.000 66.67979  ? 19  TYR   A O   1 
ATOM   54   C  CB  . TYR   A 1 19  ? 36.01896 -15.41725 40.17086  1.000 58.38322  ? 19  TYR   A CB  1 
ATOM   55   C  CG  . TYR   A 1 19  ? 34.98685 -15.93815 41.13830  1.000 61.30690  ? 19  TYR   A CG  1 
ATOM   56   C  CD1 . TYR   A 1 19  ? 35.31549 -16.19261 42.46148  1.000 66.11119  ? 19  TYR   A CD1 1 
ATOM   57   C  CD2 . TYR   A 1 19  ? 33.68577 -16.18977 40.72477  1.000 65.29910  ? 19  TYR   A CD2 1 
ATOM   58   C  CE1 . TYR   A 1 19  ? 34.37622 -16.67369 43.34733  1.000 67.26363  ? 19  TYR   A CE1 1 
ATOM   59   C  CE2 . TYR   A 1 19  ? 32.73872 -16.66991 41.60401  1.000 71.65078  ? 19  TYR   A CE2 1 
ATOM   60   C  CZ  . TYR   A 1 19  ? 33.08846 -16.91167 42.91386  1.000 71.69048  ? 19  TYR   A CZ  1 
ATOM   61   O  OH  . TYR   A 1 19  ? 32.14460 -17.39160 43.79169  1.000 69.82796  ? 19  TYR   A OH  1 
ATOM   62   N  N   . VAL   A 1 20  ? 34.58197 -12.96987 38.62464  1.000 65.11070  ? 20  VAL   A N   1 
ATOM   63   C  CA  . VAL   A 1 20  ? 33.40909 -12.21765 38.19097  1.000 57.29331  ? 20  VAL   A CA  1 
ATOM   64   C  C   . VAL   A 1 20  ? 32.29786 -13.19082 37.82433  1.000 63.08911  ? 20  VAL   A C   1 
ATOM   65   O  O   . VAL   A 1 20  ? 32.51099 -14.12353 37.03928  1.000 70.07092  ? 20  VAL   A O   1 
ATOM   66   C  CB  . VAL   A 1 20  ? 33.74454 -11.29731 37.00529  1.000 58.86863  ? 20  VAL   A CB  1 
ATOM   67   C  CG1 . VAL   A 1 20  ? 32.51848 -10.49766 36.59270  1.000 61.38831  ? 20  VAL   A CG1 1 
ATOM   68   C  CG2 . VAL   A 1 20  ? 34.89434 -10.37051 37.36414  1.000 65.55364  ? 20  VAL   A CG2 1 
ATOM   69   N  N   . ILE   A 1 21  ? 31.11336 -12.97513 38.39029  1.000 62.18748  ? 21  ILE   A N   1 
ATOM   70   C  CA  . ILE   A 1 21  ? 29.92375 -13.74123 38.03311  1.000 57.09376  ? 21  ILE   A CA  1 
ATOM   71   C  C   . ILE   A 1 21  ? 29.18475 -12.95511 36.95678  1.000 60.26616  ? 21  ILE   A C   1 
ATOM   72   O  O   . ILE   A 1 21  ? 28.63429 -11.88395 37.22476  1.000 65.80230  ? 21  ILE   A O   1 
ATOM   73   C  CB  . ILE   A 1 21  ? 29.02836 -14.00129 39.24972  1.000 54.20897  ? 21  ILE   A CB  1 
ATOM   74   C  CG1 . ILE   A 1 21  ? 29.77677 -14.83097 40.29507  1.000 57.86978  ? 21  ILE   A CG1 1 
ATOM   75   C  CG2 . ILE   A 1 21  ? 27.74805 -14.70454 38.82544  1.000 54.73551  ? 21  ILE   A CG2 1 
ATOM   76   C  CD1 . ILE   A 1 21  ? 28.95422 -15.15042 41.52436  1.000 62.78626  ? 21  ILE   A CD1 1 
ATOM   77   N  N   . ARG   A 1 22  ? 29.16902 -13.48718 35.73803  1.000 64.43302  ? 22  ARG   A N   1 
ATOM   78   C  CA  . ARG   A 1 22  ? 28.68038 -12.73774 34.58946  1.000 70.79403  ? 22  ARG   A CA  1 
ATOM   79   C  C   . ARG   A 1 22  ? 28.30036 -13.70987 33.48370  1.000 75.45315  ? 22  ARG   A C   1 
ATOM   80   O  O   . ARG   A 1 22  ? 28.55189 -14.91423 33.56975  1.000 81.83683  ? 22  ARG   A O   1 
ATOM   81   C  CB  . ARG   A 1 22  ? 29.74102 -11.75534 34.08471  1.000 68.27281  ? 22  ARG   A CB  1 
ATOM   82   C  CG  . ARG   A 1 22  ? 31.03976 -12.44752 33.68760  1.000 67.62705  ? 22  ARG   A CG  1 
ATOM   83   C  CD  . ARG   A 1 22  ? 32.05620 -11.48873 33.09238  1.000 66.25118  ? 22  ARG   A CD  1 
ATOM   84   N  NE  . ARG   A 1 22  ? 31.64251 -10.97856 31.79128  1.000 63.46233  ? 22  ARG   A NE  1 
ATOM   85   C  CZ  . ARG   A 1 22  ? 32.43817 -10.31843 30.96112  1.000 68.11776  ? 22  ARG   A CZ  1 
ATOM   86   N  NH1 . ARG   A 1 22  ? 33.70664 -10.08617 31.25771  1.000 68.19371  ? 22  ARG   A NH1 1 
ATOM   87   N  NH2 . ARG   A 1 22  ? 31.95006 -9.88323  29.80315  1.000 73.72705  ? 22  ARG   A NH2 1 
ATOM   88   N  N   . ASP   A 1 23  ? 27.68627 -13.16370 32.43863  1.000 78.14419  ? 23  ASP   A N   1 
ATOM   89   C  CA  . ASP   A 1 23  ? 27.56120 -13.88382 31.18462  1.000 78.84440  ? 23  ASP   A CA  1 
ATOM   90   C  C   . ASP   A 1 23  ? 28.88144 -13.80481 30.42381  1.000 77.14351  ? 23  ASP   A C   1 
ATOM   91   O  O   . ASP   A 1 23  ? 29.73221 -12.95361 30.69777  1.000 76.49864  ? 23  ASP   A O   1 
ATOM   92   C  CB  . ASP   A 1 23  ? 26.42067 -13.31257 30.34072  1.000 75.35655  ? 23  ASP   A CB  1 
ATOM   93   C  CG  . ASP   A 1 23  ? 25.10209 -13.27368 31.09111  1.000 76.18082  ? 23  ASP   A CG  1 
ATOM   94   O  OD1 . ASP   A 1 23  ? 24.93118 -14.06772 32.04037  1.000 71.33857  ? 23  ASP   A OD1 1 
ATOM   95   O  OD2 . ASP   A 1 23  ? 24.23563 -12.44929 30.73051  1.000 73.62331  ? 23  ASP   A OD2 1 
ATOM   96   N  N   . GLU   A 1 24  ? 29.05206 -14.71346 29.46046  1.000 80.62838  ? 24  GLU   A N   1 
ATOM   97   C  CA  . GLU   A 1 24  ? 30.31957 -14.77945 28.73817  1.000 82.22383  ? 24  GLU   A CA  1 
ATOM   98   C  C   . GLU   A 1 24  ? 30.59804 -13.48505 27.98393  1.000 81.89091  ? 24  GLU   A C   1 
ATOM   99   O  O   . GLU   A 1 24  ? 31.73886 -13.00805 27.95536  1.000 86.50720  ? 24  GLU   A O   1 
ATOM   100  C  CB  . GLU   A 1 24  ? 30.32533 -15.97172 27.78180  1.000 82.09674  ? 24  GLU   A CB  1 
ATOM   101  C  CG  . GLU   A 1 24  ? 31.62414 -16.12050 27.00305  1.000 80.28250  ? 24  GLU   A CG  1 
ATOM   102  C  CD  . GLU   A 1 24  ? 31.69631 -17.41709 26.22274  1.000 87.61567  ? 24  GLU   A CD  1 
ATOM   103  O  OE1 . GLU   A 1 24  ? 30.86808 -18.31553 26.48076  1.000 83.04170  ? 24  GLU   A OE1 1 
ATOM   104  O  OE2 . GLU   A 1 24  ? 32.58267 -17.53769 25.35084  1.000 96.77015  ? 24  GLU   A OE2 1 
ATOM   105  N  N   . VAL   A 1 25  ? 29.57132 -12.89807 27.37403  1.000 76.10513  ? 25  VAL   A N   1 
ATOM   106  C  CA  . VAL   A 1 25  ? 29.70317 -11.64641 26.63747  1.000 77.45437  ? 25  VAL   A CA  1 
ATOM   107  C  C   . VAL   A 1 25  ? 28.59334 -10.70880 27.08904  1.000 73.88398  ? 25  VAL   A C   1 
ATOM   108  O  O   . VAL   A 1 25  ? 27.40929 -10.99253 26.87099  1.000 74.58150  ? 25  VAL   A O   1 
ATOM   109  C  CB  . VAL   A 1 25  ? 29.64375 -11.85796 25.11514  1.000 69.31605  ? 25  VAL   A CB  1 
ATOM   110  C  CG1 . VAL   A 1 25  ? 29.64271 -10.51764 24.39655  1.000 78.93576  ? 25  VAL   A CG1 1 
ATOM   111  C  CG2 . VAL   A 1 25  ? 30.81341 -12.71161 24.64912  1.000 78.92191  ? 25  VAL   A CG2 1 
ATOM   112  N  N   . GLU   A 1 26  ? 28.97301 -9.59955  27.71831  1.000 68.68911  ? 26  GLU   A N   1 
ATOM   113  C  CA  . GLU   A 1 26  ? 28.02915 -8.55640  28.10437  1.000 73.05767  ? 26  GLU   A CA  1 
ATOM   114  C  C   . GLU   A 1 26  ? 27.98532 -7.51929  26.98812  1.000 80.02977  ? 26  GLU   A C   1 
ATOM   115  O  O   . GLU   A 1 26  ? 28.93136 -6.74407  26.81420  1.000 82.56225  ? 26  GLU   A O   1 
ATOM   116  C  CB  . GLU   A 1 26  ? 28.43320 -7.92287  29.43350  1.000 71.05381  ? 26  GLU   A CB  1 
ATOM   117  C  CG  . GLU   A 1 26  ? 28.39193 -8.87212  30.62227  1.000 70.37256  ? 26  GLU   A CG  1 
ATOM   118  C  CD  . GLU   A 1 26  ? 26.97801 -9.20232  31.06332  1.000 70.43024  ? 26  GLU   A CD  1 
ATOM   119  O  OE1 . GLU   A 1 26  ? 26.04023 -8.48562  30.65417  1.000 65.83837  ? 26  GLU   A OE1 1 
ATOM   120  O  OE2 . GLU   A 1 26  ? 26.80492 -10.17935 31.82226  1.000 70.44834  ? 26  GLU   A OE2 1 
ATOM   121  N  N   . LYS   A 1 27  ? 26.88800 -7.50900  26.22755  1.000 80.20680  ? 27  LYS   A N   1 
ATOM   122  C  CA  . LYS   A 1 27  ? 26.78603 -6.59789  25.09165  1.000 74.51882  ? 27  LYS   A CA  1 
ATOM   123  C  C   . LYS   A 1 27  ? 26.72539 -5.14396  25.54167  1.000 73.07355  ? 27  LYS   A C   1 
ATOM   124  O  O   . LYS   A 1 27  ? 27.31334 -4.26612  24.89950  1.000 77.70702  ? 27  LYS   A O   1 
ATOM   125  C  CB  . LYS   A 1 27  ? 25.55897 -6.93967  24.24734  1.000 78.00950  ? 27  LYS   A CB  1 
ATOM   126  C  CG  . LYS   A 1 27  ? 25.73542 -8.13744  23.33066  1.000 79.67523  ? 27  LYS   A CG  1 
ATOM   127  C  CD  . LYS   A 1 27  ? 24.56376 -8.28588  22.36275  1.000 92.88322  ? 27  LYS   A CD  1 
ATOM   128  C  CE  . LYS   A 1 27  ? 24.59670 -7.24217  21.24689  1.000 95.42159  ? 27  LYS   A CE  1 
ATOM   129  N  NZ  . LYS   A 1 27  ? 24.09054 -5.89965  21.65768  1.000 78.24415  ? 27  LYS   A NZ  1 
ATOM   130  N  N   . TYR   A 1 28  ? 26.02302 -4.86838  26.63509  1.000 76.91776  ? 28  TYR   A N   1 
ATOM   131  C  CA  . TYR   A 1 28  ? 25.78302 -3.50772  27.08709  1.000 81.15172  ? 28  TYR   A CA  1 
ATOM   132  C  C   . TYR   A 1 28  ? 26.58541 -3.21221  28.34777  1.000 78.33760  ? 28  TYR   A C   1 
ATOM   133  O  O   . TYR   A 1 28  ? 26.95005 -4.11305  29.10862  1.000 76.75806  ? 28  TYR   A O   1 
ATOM   134  C  CB  . TYR   A 1 28  ? 24.29011 -3.27812  27.34351  1.000 79.66644  ? 28  TYR   A CB  1 
ATOM   135  C  CG  . TYR   A 1 28  ? 23.39878 -3.89159  26.28796  1.000 86.11742  ? 28  TYR   A CG  1 
ATOM   136  C  CD1 . TYR   A 1 28  ? 23.34081 -3.36134  25.00565  1.000 86.82440  ? 28  TYR   A CD1 1 
ATOM   137  C  CD2 . TYR   A 1 28  ? 22.61676 -5.00307  26.57326  1.000 94.36519  ? 28  TYR   A CD2 1 
ATOM   138  C  CE1 . TYR   A 1 28  ? 22.52910 -3.92154  24.03675  1.000 94.00412  ? 28  TYR   A CE1 1 
ATOM   139  C  CE2 . TYR   A 1 28  ? 21.80131 -5.56944  25.61165  1.000 99.19156  ? 28  TYR   A CE2 1 
ATOM   140  C  CZ  . TYR   A 1 28  ? 21.76116 -5.02506  24.34551  1.000 100.46470 ? 28  TYR   A CZ  1 
ATOM   141  O  OH  . TYR   A 1 28  ? 20.95049 -5.58663  23.38586  1.000 102.64797 ? 28  TYR   A OH  1 
ATOM   142  N  N   . ASN   A 1 29  ? 26.85599 -1.92569  28.55838  1.000 79.63412  ? 29  ASN   A N   1 
ATOM   143  C  CA  . ASN   A 1 29  ? 27.65190 -1.49365  29.70057  1.000 79.61708  ? 29  ASN   A CA  1 
ATOM   144  C  C   . ASN   A 1 29  ? 26.85401 -1.65777  30.98743  1.000 72.92321  ? 29  ASN   A C   1 
ATOM   145  O  O   . ASN   A 1 29  ? 25.80832 -1.02443  31.16280  1.000 75.04179  ? 29  ASN   A O   1 
ATOM   146  C  CB  . ASN   A 1 29  ? 28.08644 -0.04002  29.52540  1.000 73.46998  ? 29  ASN   A CB  1 
ATOM   147  C  CG  . ASN   A 1 29  ? 28.92029 0.17508   28.27778  1.000 72.19363  ? 29  ASN   A CG  1 
ATOM   148  O  OD1 . ASN   A 1 29  ? 30.13559 -0.02417  28.28656  1.000 65.24947  ? 29  ASN   A OD1 1 
ATOM   149  N  ND2 . ASN   A 1 29  ? 28.27077 0.59143   27.19711  1.000 76.12736  ? 29  ASN   A ND2 1 
ATOM   150  N  N   . ARG   A 1 30  ? 27.34841 -2.50190  31.88994  1.000 65.39840  ? 30  ARG   A N   1 
ATOM   151  C  CA  . ARG   A 1 30  ? 26.73444 -2.67139  33.19989  1.000 67.91356  ? 30  ARG   A CA  1 
ATOM   152  C  C   . ARG   A 1 30  ? 27.10073 -1.55121  34.16710  1.000 69.80327  ? 30  ARG   A C   1 
ATOM   153  O  O   . ARG   A 1 30  ? 26.82197 -1.66915  35.36479  1.000 69.35423  ? 30  ARG   A O   1 
ATOM   154  C  CB  . ARG   A 1 30  ? 27.12853 -4.02608  33.79580  1.000 69.39210  ? 30  ARG   A CB  1 
ATOM   155  C  CG  . ARG   A 1 30  ? 26.92727 -5.20428  32.85218  1.000 78.31324  ? 30  ARG   A CG  1 
ATOM   156  C  CD  . ARG   A 1 30  ? 25.46237 -5.40046  32.48331  1.000 85.85521  ? 30  ARG   A CD  1 
ATOM   157  N  NE  . ARG   A 1 30  ? 24.67796 -5.93608  33.58989  1.000 85.31386  ? 30  ARG   A NE  1 
ATOM   158  C  CZ  . ARG   A 1 30  ? 23.42074 -6.34608  33.48714  1.000 84.68596  ? 30  ARG   A CZ  1 
ATOM   159  N  NH1 . ARG   A 1 30  ? 22.76925 -6.29715  32.33653  1.000 81.90017  ? 30  ARG   A NH1 1 
ATOM   160  N  NH2 . ARG   A 1 30  ? 22.80258 -6.82045  34.56507  1.000 89.14124  ? 30  ARG   A NH2 1 
ATOM   161  N  N   . ASN   A 1 31  ? 27.71873 -0.47960  33.67603  1.000 70.24584  ? 31  ASN   A N   1 
ATOM   162  C  CA  . ASN   A 1 31  ? 28.07420 0.66655   34.50114  1.000 67.83100  ? 31  ASN   A CA  1 
ATOM   163  C  C   . ASN   A 1 31  ? 28.26453 1.86753   33.58459  1.000 63.59458  ? 31  ASN   A C   1 
ATOM   164  O  O   . ASN   A 1 31  ? 28.21275 1.75124   32.35779  1.000 64.59505  ? 31  ASN   A O   1 
ATOM   165  C  CB  . ASN   A 1 31  ? 29.33538 0.39215   35.32813  1.000 64.60260  ? 31  ASN   A CB  1 
ATOM   166  C  CG  . ASN   A 1 31  ? 29.43827 1.28445   36.55085  1.000 58.83147  ? 31  ASN   A CG  1 
ATOM   167  O  OD1 . ASN   A 1 31  ? 28.79050 2.32814   36.62843  1.000 52.32583  ? 31  ASN   A OD1 1 
ATOM   168  N  ND2 . ASN   A 1 31  ? 30.25944 0.87863   37.51208  1.000 61.52717  ? 31  ASN   A ND2 1 
ATOM   169  N  N   . GLY   A 1 32  ? 28.48655 3.02688   34.19793  1.000 62.43593  ? 32  GLY   A N   1 
ATOM   170  C  CA  . GLY   A 1 32  ? 28.68452 4.24684   33.44344  1.000 59.81732  ? 32  GLY   A CA  1 
ATOM   171  C  C   . GLY   A 1 32  ? 29.97196 4.23390   32.63952  1.000 59.34508  ? 32  GLY   A C   1 
ATOM   172  O  O   . GLY   A 1 32  ? 30.82370 3.35404   32.76643  1.000 65.52440  ? 32  GLY   A O   1 
ATOM   173  N  N   . VAL   A 1 33  ? 30.11080 5.24795   31.78899  1.000 54.73989  ? 33  VAL   A N   1 
ATOM   174  C  CA  . VAL   A 1 33  ? 31.25536 5.39162   30.89564  1.000 60.55822  ? 33  VAL   A CA  1 
ATOM   175  C  C   . VAL   A 1 33  ? 32.03795 6.62954   31.31104  1.000 57.25937  ? 33  VAL   A C   1 
ATOM   176  O  O   . VAL   A 1 33  ? 31.44962 7.69056   31.55301  1.000 55.68610  ? 33  VAL   A O   1 
ATOM   177  C  CB  . VAL   A 1 33  ? 30.81022 5.48537   29.42577  1.000 57.22903  ? 33  VAL   A CB  1 
ATOM   178  C  CG1 . VAL   A 1 33  ? 32.01392 5.62408   28.51115  1.000 62.54541  ? 33  VAL   A CG1 1 
ATOM   179  C  CG2 . VAL   A 1 33  ? 29.98359 4.26708   29.04449  1.000 61.52271  ? 33  VAL   A CG2 1 
ATOM   180  N  N   . ASN   A 1 34  ? 33.36408 6.49627   31.38940  1.000 55.78599  ? 34  ASN   A N   1 
ATOM   181  C  CA  . ASN   A 1 34  ? 34.21790 7.58825   31.83847  1.000 55.70199  ? 34  ASN   A CA  1 
ATOM   182  C  C   . ASN   A 1 34  ? 34.89973 8.34391   30.70623  1.000 66.28276  ? 34  ASN   A C   1 
ATOM   183  O  O   . ASN   A 1 34  ? 35.33273 9.48107   30.92154  1.000 73.40489  ? 34  ASN   A O   1 
ATOM   184  C  CB  . ASN   A 1 34  ? 35.29618 7.06702   32.79584  1.000 58.94564  ? 34  ASN   A CB  1 
ATOM   185  C  CG  . ASN   A 1 34  ? 34.73621 6.66496   34.14338  1.000 65.40438  ? 34  ASN   A CG  1 
ATOM   186  O  OD1 . ASN   A 1 34  ? 33.64876 7.09307   34.52967  1.000 64.23565  ? 34  ASN   A OD1 1 
ATOM   187  N  ND2 . ASN   A 1 34  ? 35.48391 5.84456   34.87331  1.000 68.70322  ? 34  ASN   A ND2 1 
ATOM   188  N  N   . ALA   A 1 35  ? 35.01698 7.75203   29.51927  1.000 66.01060  ? 35  ALA   A N   1 
ATOM   189  C  CA  . ALA   A 1 35  ? 35.69738 8.41567   28.41700  1.000 66.92874  ? 35  ALA   A CA  1 
ATOM   190  C  C   . ALA   A 1 35  ? 35.16608 7.88592   27.09503  1.000 63.11067  ? 35  ALA   A C   1 
ATOM   191  O  O   . ALA   A 1 35  ? 34.60853 6.78768   27.01981  1.000 62.58817  ? 35  ALA   A O   1 
ATOM   192  C  CB  . ALA   A 1 35  ? 37.21562 8.22554   28.49450  1.000 71.19451  ? 35  ALA   A CB  1 
ATOM   193  N  N   . LEU   A 1 36  ? 35.36197 8.68284   26.04573  1.000 66.70628  ? 36  LEU   A N   1 
ATOM   194  C  CA  . LEU   A 1 36  ? 34.88232 8.36340   24.71005  1.000 67.27723  ? 36  LEU   A CA  1 
ATOM   195  C  C   . LEU   A 1 36  ? 35.98810 8.59992   23.69157  1.000 68.80290  ? 36  LEU   A C   1 
ATOM   196  O  O   . LEU   A 1 36  ? 36.78741 9.53125   23.83103  1.000 75.59079  ? 36  LEU   A O   1 
ATOM   197  C  CB  . LEU   A 1 36  ? 33.65452 9.20763   24.34523  1.000 66.91448  ? 36  LEU   A CB  1 
ATOM   198  C  CG  . LEU   A 1 36  ? 32.41960 9.05852   25.23751  1.000 65.32634  ? 36  LEU   A CG  1 
ATOM   199  C  CD1 . LEU   A 1 36  ? 31.34291 10.05633  24.83742  1.000 65.49383  ? 36  LEU   A CD1 1 
ATOM   200  C  CD2 . LEU   A 1 36  ? 31.88462 7.63735   25.17468  1.000 66.32278  ? 36  LEU   A CD2 1 
ATOM   201  N  N   . GLN   A 1 37  ? 36.02642 7.74986   22.66731  1.000 65.33713  ? 37  GLN   A N   1 
ATOM   202  C  CA  . GLN   A 1 37  ? 36.94940 7.89660   21.55119  1.000 70.68464  ? 37  GLN   A CA  1 
ATOM   203  C  C   . GLN   A 1 37  ? 36.23217 7.51401   20.26693  1.000 77.05866  ? 37  GLN   A C   1 
ATOM   204  O  O   . GLN   A 1 37  ? 35.49379 6.52606   20.23184  1.000 74.91036  ? 37  GLN   A O   1 
ATOM   205  C  CB  . GLN   A 1 37  ? 38.20633 7.03400   21.73175  1.000 68.80489  ? 37  GLN   A CB  1 
ATOM   206  C  CG  . GLN   A 1 37  ? 39.34365 7.72522   22.47130  1.000 67.55395  ? 37  GLN   A CG  1 
ATOM   207  C  CD  . GLN   A 1 37  ? 40.05474 8.76856   21.62307  1.000 77.00123  ? 37  GLN   A CD  1 
ATOM   208  O  OE1 . GLN   A 1 37  ? 39.72387 8.97095   20.45396  1.000 80.67011  ? 37  GLN   A OE1 1 
ATOM   209  N  NE2 . GLN   A 1 37  ? 41.04216 9.43387   22.21172  1.000 78.40659  ? 37  GLN   A NE2 1 
ATOM   210  N  N   . LEU   A 1 38  ? 36.45559 8.29597   19.21469  1.000 78.06751  ? 38  LEU   A N   1 
ATOM   211  C  CA  . LEU   A 1 38  ? 35.75312 8.13023   17.95145  1.000 76.88082  ? 38  LEU   A CA  1 
ATOM   212  C  C   . LEU   A 1 38  ? 36.74661 7.88011   16.82491  1.000 82.59896  ? 38  LEU   A C   1 
ATOM   213  O  O   . LEU   A 1 38  ? 37.77781 8.55364   16.73131  1.000 84.36829  ? 38  LEU   A O   1 
ATOM   214  C  CB  . LEU   A 1 38  ? 34.90330 9.36647   17.63674  1.000 67.85282  ? 38  LEU   A CB  1 
ATOM   215  C  CG  . LEU   A 1 38  ? 33.69885 9.16898   16.71539  1.000 71.39563  ? 38  LEU   A CG  1 
ATOM   216  C  CD1 . LEU   A 1 38  ? 32.67056 8.26019   17.37015  1.000 69.36469  ? 38  LEU   A CD1 1 
ATOM   217  C  CD2 . LEU   A 1 38  ? 33.07778 10.50760  16.34939  1.000 62.79658  ? 38  LEU   A CD2 1 
ATOM   218  N  N   . ASP   A 1 39  ? 36.42748 6.90597   15.97010  1.000 83.79132  ? 39  ASP   A N   1 
ATOM   219  C  CA  . ASP   A 1 39  ? 37.23032 6.61566   14.79161  1.000 87.36002  ? 39  ASP   A CA  1 
ATOM   220  C  C   . ASP   A 1 39  ? 36.52536 7.18900   13.57432  1.000 86.09296  ? 39  ASP   A C   1 
ATOM   221  O  O   . ASP   A 1 39  ? 35.46498 6.67445   13.18513  1.000 82.89958  ? 39  ASP   A O   1 
ATOM   222  C  CB  . ASP   A 1 39  ? 37.43647 5.10864   14.63382  1.000 95.04482  ? 39  ASP   A CB  1 
ATOM   223  C  CG  . ASP   A 1 39  ? 38.55773 4.76491   13.66253  1.000 94.22525  ? 39  ASP   A CG  1 
ATOM   224  O  OD1 . ASP   A 1 39  ? 38.73680 5.49049   12.66194  1.000 91.26825  ? 39  ASP   A OD1 1 
ATOM   225  O  OD2 . ASP   A 1 39  ? 39.26544 3.76345   13.90185  1.000 88.41045  ? 39  ASP   A OD2 1 
ATOM   226  N  N   . PRO   A 1 40  ? 37.05940 8.23507   12.93864  1.000 90.10237  ? 40  PRO   A N   1 
ATOM   227  C  CA  . PRO   A 1 40  ? 36.33527 8.88184   11.83590  1.000 95.59540  ? 40  PRO   A CA  1 
ATOM   228  C  C   . PRO   A 1 40  ? 36.34461 8.07430   10.54674  1.000 99.33367  ? 40  PRO   A C   1 
ATOM   229  O  O   . PRO   A 1 40  ? 35.34310 8.03493   9.82517   1.000 98.85782  ? 40  PRO   A O   1 
ATOM   230  C  CB  . PRO   A 1 40  ? 37.08033 10.21152  11.66850  1.000 90.50652  ? 40  PRO   A CB  1 
ATOM   231  C  CG  . PRO   A 1 40  ? 38.46968 9.91497   12.12963  1.000 82.68284  ? 40  PRO   A CG  1 
ATOM   232  C  CD  . PRO   A 1 40  ? 38.33184 8.91364   13.24767  1.000 83.38602  ? 40  PRO   A CD  1 
ATOM   233  N  N   . ALA   A 1 41  ? 37.47284 7.42863   10.24585  1.000 100.37572 ? 41  ALA   A N   1 
ATOM   234  C  CA  . ALA   A 1 41  ? 37.59682 6.71345   8.98077   1.000 97.33179  ? 41  ALA   A CA  1 
ATOM   235  C  C   . ALA   A 1 41  ? 36.76847 5.43590   8.96670   1.000 93.11632  ? 41  ALA   A C   1 
ATOM   236  O  O   . ALA   A 1 41  ? 36.26066 5.04086   7.91107   1.000 88.96567  ? 41  ALA   A O   1 
ATOM   237  C  CB  . ALA   A 1 41  ? 39.06596 6.39731   8.69794   1.000 96.08515  ? 41  ALA   A CB  1 
ATOM   238  N  N   . LEU   A 1 42  ? 36.61077 4.78610   10.11686  1.000 91.53772  ? 42  LEU   A N   1 
ATOM   239  C  CA  . LEU   A 1 42  ? 35.91902 3.50809   10.19878  1.000 96.23638  ? 42  LEU   A CA  1 
ATOM   240  C  C   . LEU   A 1 42  ? 34.51570 3.61900   10.78195  1.000 91.15323  ? 42  LEU   A C   1 
ATOM   241  O  O   . LEU   A 1 42  ? 33.80422 2.61035   10.83316  1.000 87.88374  ? 42  LEU   A O   1 
ATOM   242  C  CB  . LEU   A 1 42  ? 36.74606 2.51997   11.02795  1.000 91.85231  ? 42  LEU   A CB  1 
ATOM   243  C  CG  . LEU   A 1 42  ? 38.19804 2.31115   10.59286  1.000 92.00962  ? 42  LEU   A CG  1 
ATOM   244  C  CD1 . LEU   A 1 42  ? 38.89386 1.31032   11.50295  1.000 86.05906  ? 42  LEU   A CD1 1 
ATOM   245  C  CD2 . LEU   A 1 42  ? 38.26955 1.86183   9.14088   1.000 101.36066 ? 42  LEU   A CD2 1 
ATOM   246  N  N   . ASN   A 1 43  ? 34.10252 4.81196   11.21597  1.000 86.48518  ? 43  ASN   A N   1 
ATOM   247  C  CA  . ASN   A 1 43  ? 32.79000 5.03545   11.82596  1.000 86.88529  ? 43  ASN   A CA  1 
ATOM   248  C  C   . ASN   A 1 43  ? 32.56986 4.09942   13.01686  1.000 89.78965  ? 43  ASN   A C   1 
ATOM   249  O  O   . ASN   A 1 43  ? 31.59577 3.34617   13.08450  1.000 86.10452  ? 43  ASN   A O   1 
ATOM   250  C  CB  . ASN   A 1 43  ? 31.66736 4.88707   10.79224  1.000 85.40955  ? 43  ASN   A CB  1 
ATOM   251  C  CG  . ASN   A 1 43  ? 31.29457 6.20449   10.14216  1.000 84.58476  ? 43  ASN   A CG  1 
ATOM   252  O  OD1 . ASN   A 1 43  ? 32.11063 7.12168   10.05662  1.000 84.80646  ? 43  ASN   A OD1 1 
ATOM   253  N  ND2 . ASN   A 1 43  ? 30.05125 6.30731   9.68624   1.000 84.84620  ? 43  ASN   A ND2 1 
ATOM   254  N  N   . ARG   A 1 44  ? 33.50312 4.16249   13.96447  1.000 92.16910  ? 44  ARG   A N   1 
ATOM   255  C  CA  . ARG   A 1 44  ? 33.46852 3.32365   15.15218  1.000 91.60698  ? 44  ARG   A CA  1 
ATOM   256  C  C   . ARG   A 1 44  ? 33.65189 4.18258   16.39510  1.000 81.32894  ? 44  ARG   A C   1 
ATOM   257  O  O   . ARG   A 1 44  ? 34.37657 5.18136   16.38159  1.000 81.42242  ? 44  ARG   A O   1 
ATOM   258  C  CB  . ARG   A 1 44  ? 34.54645 2.23070   15.09525  1.000 103.56325 ? 44  ARG   A CB  1 
ATOM   259  C  CG  . ARG   A 1 44  ? 34.38718 1.27963   13.91687  1.000 110.42963 ? 44  ARG   A CG  1 
ATOM   260  C  CD  . ARG   A 1 44  ? 35.63670 0.44455   13.68859  1.000 111.31004 ? 44  ARG   A CD  1 
ATOM   261  N  NE  . ARG   A 1 44  ? 35.78838 -0.62499  14.66701  1.000 115.65080 ? 44  ARG   A NE  1 
ATOM   262  C  CZ  . ARG   A 1 44  ? 36.83591 -1.43578  14.72836  1.000 114.86618 ? 44  ARG   A CZ  1 
ATOM   263  N  NH1 . ARG   A 1 44  ? 37.85412 -1.31385  13.89210  1.000 113.15760 ? 44  ARG   A NH1 1 
ATOM   264  N  NH2 . ARG   A 1 44  ? 36.86352 -2.39187  15.65236  1.000 114.49607 ? 44  ARG   A NH2 1 
ATOM   265  N  N   . LEU   A 1 45  ? 32.98166 3.77945   17.47094  1.000 80.16446  ? 45  LEU   A N   1 
ATOM   266  C  CA  . LEU   A 1 45  ? 32.99222 4.49950   18.73724  1.000 74.73894  ? 45  LEU   A CA  1 
ATOM   267  C  C   . LEU   A 1 45  ? 33.48167 3.57296   19.83925  1.000 73.01686  ? 45  LEU   A C   1 
ATOM   268  O  O   . LEU   A 1 45  ? 33.02745 2.42947   19.94010  1.000 76.00738  ? 45  LEU   A O   1 
ATOM   269  C  CB  . LEU   A 1 45  ? 31.59748 5.03383   19.07580  1.000 72.93946  ? 45  LEU   A CB  1 
ATOM   270  C  CG  . LEU   A 1 45  ? 31.37638 5.59317   20.48340  1.000 72.37336  ? 45  LEU   A CG  1 
ATOM   271  C  CD1 . LEU   A 1 45  ? 32.28406 6.78261   20.74692  1.000 73.79733  ? 45  LEU   A CD1 1 
ATOM   272  C  CD2 . LEU   A 1 45  ? 29.91805 5.97547   20.68258  1.000 73.89778  ? 45  LEU   A CD2 1 
ATOM   273  N  N   . PHE   A 1 46  ? 34.39881 4.06839   20.66377  1.000 69.43651  ? 46  PHE   A N   1 
ATOM   274  C  CA  . PHE   A 1 46  ? 34.96510 3.30702   21.76986  1.000 69.05317  ? 46  PHE   A CA  1 
ATOM   275  C  C   . PHE   A 1 46  ? 34.47588 3.90868   23.07971  1.000 71.61901  ? 46  PHE   A C   1 
ATOM   276  O  O   . PHE   A 1 46  ? 34.78577 5.06452   23.38861  1.000 82.91963  ? 46  PHE   A O   1 
ATOM   277  C  CB  . PHE   A 1 46  ? 36.49319 3.30962   21.71200  1.000 69.20699  ? 46  PHE   A CB  1 
ATOM   278  C  CG  . PHE   A 1 46  ? 37.05677 2.61453   20.50489  1.000 79.71205  ? 46  PHE   A CG  1 
ATOM   279  C  CD1 . PHE   A 1 46  ? 37.10348 3.25532   19.27718  1.000 90.07765  ? 46  PHE   A CD1 1 
ATOM   280  C  CD2 . PHE   A 1 46  ? 37.54562 1.32238   20.59897  1.000 80.80026  ? 46  PHE   A CD2 1 
ATOM   281  C  CE1 . PHE   A 1 46  ? 37.62135 2.61867   18.16529  1.000 92.31110  ? 46  PHE   A CE1 1 
ATOM   282  C  CE2 . PHE   A 1 46  ? 38.06799 0.68186   19.49033  1.000 89.33894  ? 46  PHE   A CE2 1 
ATOM   283  C  CZ  . PHE   A 1 46  ? 38.10451 1.33032   18.27240  1.000 91.71668  ? 46  PHE   A CZ  1 
ATOM   284  N  N   . THR   A 1 47  ? 33.71234 3.13027   23.84178  1.000 67.85895  ? 47  THR   A N   1 
ATOM   285  C  CA  . THR   A 1 47  ? 33.19228 3.55519   25.13480  1.000 64.71964  ? 47  THR   A CA  1 
ATOM   286  C  C   . THR   A 1 47  ? 33.97280 2.84813   26.23357  1.000 67.42615  ? 47  THR   A C   1 
ATOM   287  O  O   . THR   A 1 47  ? 34.03805 1.61280   26.25754  1.000 73.36728  ? 47  THR   A O   1 
ATOM   288  C  CB  . THR   A 1 47  ? 31.69933 3.25154   25.26023  1.000 66.66292  ? 47  THR   A CB  1 
ATOM   289  O  OG1 . THR   A 1 47  ? 31.49211 1.83397   25.21843  1.000 79.86591  ? 47  THR   A OG1 1 
ATOM   290  C  CG2 . THR   A 1 47  ? 30.92588 3.90782   24.12716  1.000 66.29419  ? 47  THR   A CG2 1 
ATOM   291  N  N   . ALA   A 1 48  ? 34.55992 3.63359   27.13509  1.000 63.04219  ? 48  ALA   A N   1 
ATOM   292  C  CA  . ALA   A 1 48  ? 35.33295 3.11933   28.26426  1.000 67.30273  ? 48  ALA   A CA  1 
ATOM   293  C  C   . ALA   A 1 48  ? 34.40809 3.07333   29.47613  1.000 70.29668  ? 48  ALA   A C   1 
ATOM   294  O  O   . ALA   A 1 48  ? 34.36147 4.00165   30.28463  1.000 70.57212  ? 48  ALA   A O   1 
ATOM   295  C  CB  . ALA   A 1 48  ? 36.56126 3.98452   28.51975  1.000 64.40367  ? 48  ALA   A CB  1 
ATOM   296  N  N   . GLY   A 1 49  ? 33.66595 1.97652   29.59885  1.000 72.00597  ? 49  GLY   A N   1 
ATOM   297  C  CA  . GLY   A 1 49  ? 32.72015 1.85182   30.68818  1.000 65.49525  ? 49  GLY   A CA  1 
ATOM   298  C  C   . GLY   A 1 49  ? 33.40230 1.57217   32.01369  1.000 62.74896  ? 49  GLY   A C   1 
ATOM   299  O  O   . GLY   A 1 49  ? 34.50066 1.01957   32.07750  1.000 63.46236  ? 49  GLY   A O   1 
ATOM   300  N  N   . ARG   A 1 50  ? 32.72778 1.96709   33.09534  1.000 61.11070  ? 50  ARG   A N   1 
ATOM   301  C  CA  . ARG   A 1 50  ? 33.22528 1.69520   34.43785  1.000 61.07732  ? 50  ARG   A CA  1 
ATOM   302  C  C   . ARG   A 1 50  ? 33.12449 0.22414   34.81522  1.000 68.21734  ? 50  ARG   A C   1 
ATOM   303  O  O   . ARG   A 1 50  ? 33.62541 -0.15957  35.87763  1.000 71.64222  ? 50  ARG   A O   1 
ATOM   304  C  CB  . ARG   A 1 50  ? 32.46781 2.54430   35.46052  1.000 64.26667  ? 50  ARG   A CB  1 
ATOM   305  C  CG  . ARG   A 1 50  ? 32.80931 4.02293   35.40902  1.000 68.66772  ? 50  ARG   A CG  1 
ATOM   306  C  CD  . ARG   A 1 50  ? 31.89864 4.84296   36.30868  1.000 64.36065  ? 50  ARG   A CD  1 
ATOM   307  N  NE  . ARG   A 1 50  ? 32.39898 6.20002   36.49405  1.000 57.56745  ? 50  ARG   A NE  1 
ATOM   308  C  CZ  . ARG   A 1 50  ? 31.72496 7.17283   37.09195  1.000 57.98141  ? 50  ARG   A CZ  1 
ATOM   309  N  NH1 . ARG   A 1 50  ? 30.49995 6.98238   37.55364  1.000 64.39026  ? 50  ARG   A NH1 1 
ATOM   310  N  NH2 . ARG   A 1 50  ? 32.29326 8.36775   37.22744  1.000 52.37086  ? 50  ARG   A NH2 1 
ATOM   311  N  N   . ASP   A 1 51  ? 32.49425 -0.60203  33.98006  1.000 69.43963  ? 51  ASP   A N   1 
ATOM   312  C  CA  . ASP   A 1 51  ? 32.38290 -2.03259  34.22188  1.000 69.96613  ? 51  ASP   A CA  1 
ATOM   313  C  C   . ASP   A 1 51  ? 33.58151 -2.81277  33.69307  1.000 69.94272  ? 51  ASP   A C   1 
ATOM   314  O  O   . ASP   A 1 51  ? 33.45219 -4.01013  33.41126  1.000 76.34145  ? 51  ASP   A O   1 
ATOM   315  C  CB  . ASP   A 1 51  ? 31.08881 -2.57176  33.60765  1.000 67.53274  ? 51  ASP   A CB  1 
ATOM   316  C  CG  . ASP   A 1 51  ? 31.00100 -2.31779  32.11660  1.000 66.01451  ? 51  ASP   A CG  1 
ATOM   317  O  OD1 . ASP   A 1 51  ? 31.59521 -1.32578  31.64443  1.000 68.84975  ? 51  ASP   A OD1 1 
ATOM   318  O  OD2 . ASP   A 1 51  ? 30.33543 -3.10947  31.41673  1.000 63.69839  ? 51  ASP   A OD2 1 
ATOM   319  N  N   . SER   A 1 52  ? 34.73471 -2.15581  33.54343  1.000 69.17120  ? 52  SER   A N   1 
ATOM   320  C  CA  . SER   A 1 52  ? 35.98491 -2.80246  33.13992  1.000 71.97674  ? 52  SER   A CA  1 
ATOM   321  C  C   . SER   A 1 52  ? 35.89112 -3.41360  31.74539  1.000 72.28383  ? 52  SER   A C   1 
ATOM   322  O  O   . SER   A 1 52  ? 36.58689 -4.38369  31.43431  1.000 73.67503  ? 52  SER   A O   1 
ATOM   323  C  CB  . SER   A 1 52  ? 36.41156 -3.86509  34.15677  1.000 75.52449  ? 52  SER   A CB  1 
ATOM   324  O  OG  . SER   A 1 52  ? 36.24583 -3.38729  35.47921  1.000 76.40104  ? 52  SER   A OG  1 
ATOM   325  N  N   . ILE   A 1 53  ? 35.03463 -2.85418  30.89241  1.000 67.55642  ? 53  ILE   A N   1 
ATOM   326  C  CA  . ILE   A 1 53  ? 34.81503 -3.37860  29.54856  1.000 70.16950  ? 53  ILE   A CA  1 
ATOM   327  C  C   . ILE   A 1 53  ? 34.79250 -2.20918  28.57468  1.000 69.77790  ? 53  ILE   A C   1 
ATOM   328  O  O   . ILE   A 1 53  ? 33.93746 -1.32315  28.68440  1.000 71.17711  ? 53  ILE   A O   1 
ATOM   329  C  CB  . ILE   A 1 53  ? 33.50824 -4.18502  29.44265  1.000 70.78777  ? 53  ILE   A CB  1 
ATOM   330  C  CG1 . ILE   A 1 53  ? 33.54550 -5.39766  30.37699  1.000 77.35732  ? 53  ILE   A CG1 1 
ATOM   331  C  CG2 . ILE   A 1 53  ? 33.26931 -4.62000  28.00515  1.000 73.97750  ? 53  ILE   A CG2 1 
ATOM   332  C  CD1 . ILE   A 1 53  ? 32.26443 -6.20194  30.39296  1.000 75.21241  ? 53  ILE   A CD1 1 
ATOM   333  N  N   . ILE   A 1 54  ? 35.72426 -2.20412  27.62673  1.000 69.07769  ? 54  ILE   A N   1 
ATOM   334  C  CA  . ILE   A 1 54  ? 35.76170 -1.19504  26.57394  1.000 69.15319  ? 54  ILE   A CA  1 
ATOM   335  C  C   . ILE   A 1 54  ? 34.97892 -1.72918  25.38306  1.000 72.45638  ? 54  ILE   A C   1 
ATOM   336  O  O   . ILE   A 1 54  ? 35.34106 -2.75671  24.80245  1.000 73.23524  ? 54  ILE   A O   1 
ATOM   337  C  CB  . ILE   A 1 54  ? 37.20520 -0.85607  26.17790  1.000 70.34954  ? 54  ILE   A CB  1 
ATOM   338  C  CG1 . ILE   A 1 54  ? 37.98682 -0.36391  27.39492  1.000 65.61566  ? 54  ILE   A CG1 1 
ATOM   339  C  CG2 . ILE   A 1 54  ? 37.22322 0.18453   25.06768  1.000 67.82509  ? 54  ILE   A CG2 1 
ATOM   340  C  CD1 . ILE   A 1 54  ? 39.44735 -0.14729  27.11700  1.000 65.54939  ? 54  ILE   A CD1 1 
ATOM   341  N  N   . ARG   A 1 55  ? 33.90855 -1.03708  25.01339  1.000 74.45848  ? 55  ARG   A N   1 
ATOM   342  C  CA  . ARG   A 1 55  ? 32.98541 -1.53363  24.00158  1.000 75.17807  ? 55  ARG   A CA  1 
ATOM   343  C  C   . ARG   A 1 55  ? 33.10123 -0.71748  22.72176  1.000 74.73907  ? 55  ARG   A C   1 
ATOM   344  O  O   . ARG   A 1 55  ? 33.07792 0.51749   22.75842  1.000 76.05720  ? 55  ARG   A O   1 
ATOM   345  C  CB  . ARG   A 1 55  ? 31.54884 -1.51946  24.52594  1.000 75.08214  ? 55  ARG   A CB  1 
ATOM   346  C  CG  . ARG   A 1 55  ? 31.27822 -2.62117  25.53882  1.000 70.42560  ? 55  ARG   A CG  1 
ATOM   347  C  CD  . ARG   A 1 55  ? 29.87305 -2.54300  26.10065  1.000 72.27790  ? 55  ARG   A CD  1 
ATOM   348  N  NE  . ARG   A 1 55  ? 29.58093 -3.66284  26.98687  1.000 70.03164  ? 55  ARG   A NE  1 
ATOM   349  C  CZ  . ARG   A 1 55  ? 29.92471 -3.71346  28.26621  1.000 65.46666  ? 55  ARG   A CZ  1 
ATOM   350  N  NH1 . ARG   A 1 55  ? 30.59001 -2.72584  28.84250  1.000 68.02839  ? 55  ARG   A NH1 1 
ATOM   351  N  NH2 . ARG   A 1 55  ? 29.59271 -4.78155  28.98537  1.000 63.82141  ? 55  ARG   A NH2 1 
ATOM   352  N  N   . ILE   A 1 56  ? 33.23158 -1.41594  21.59612  1.000 74.05464  ? 56  ILE   A N   1 
ATOM   353  C  CA  . ILE   A 1 56  ? 33.29997 -0.80411  20.27594  1.000 70.11646  ? 56  ILE   A CA  1 
ATOM   354  C  C   . ILE   A 1 56  ? 31.93282 -0.93441  19.62419  1.000 75.49529  ? 56  ILE   A C   1 
ATOM   355  O  O   . ILE   A 1 56  ? 31.37069 -2.03734  19.56532  1.000 82.35049  ? 56  ILE   A O   1 
ATOM   356  C  CB  . ILE   A 1 56  ? 34.38147 -1.46864  19.40761  1.000 67.75924  ? 56  ILE   A CB  1 
ATOM   357  C  CG1 . ILE   A 1 56  ? 35.63405 -1.75763  20.23536  1.000 70.77439  ? 56  ILE   A CG1 1 
ATOM   358  C  CG2 . ILE   A 1 56  ? 34.71768 -0.58999  18.21221  1.000 74.14421  ? 56  ILE   A CG2 1 
ATOM   359  C  CD1 . ILE   A 1 56  ? 36.67688 -2.56462  19.49275  1.000 64.82937  ? 56  ILE   A CD1 1 
ATOM   360  N  N   . TRP   A 1 57  ? 31.40889 0.18675   19.12892  1.000 75.71803  ? 57  TRP   A N   1 
ATOM   361  C  CA  . TRP   A 1 57  ? 30.10814 0.26694   18.48055  1.000 83.55590  ? 57  TRP   A CA  1 
ATOM   362  C  C   . TRP   A 1 57  ? 30.25841 0.93319   17.11892  1.000 83.76084  ? 57  TRP   A C   1 
ATOM   363  O  O   . TRP   A 1 57  ? 31.29181 1.52775   16.80390  1.000 83.61789  ? 57  TRP   A O   1 
ATOM   364  C  CB  . TRP   A 1 57  ? 29.09976 1.06528   19.32001  1.000 82.37148  ? 57  TRP   A CB  1 
ATOM   365  C  CG  . TRP   A 1 57  ? 29.16558 0.82006   20.79238  1.000 79.18387  ? 57  TRP   A CG  1 
ATOM   366  C  CD1 . TRP   A 1 57  ? 30.08667 1.31927   21.66678  1.000 74.40335  ? 57  TRP   A CD1 1 
ATOM   367  C  CD2 . TRP   A 1 57  ? 28.25364 0.03910   21.57243  1.000 85.42364  ? 57  TRP   A CD2 1 
ATOM   368  N  NE1 . TRP   A 1 57  ? 29.81326 0.88502   22.94039  1.000 78.34883  ? 57  TRP   A NE1 1 
ATOM   369  C  CE2 . TRP   A 1 57  ? 28.69200 0.09818   22.90962  1.000 81.29662  ? 57  TRP   A CE2 1 
ATOM   370  C  CE3 . TRP   A 1 57  ? 27.11284 -0.71034  21.26883  1.000 89.28871  ? 57  TRP   A CE3 1 
ATOM   371  C  CZ2 . TRP   A 1 57  ? 28.02960 -0.56212  23.94147  1.000 83.85224  ? 57  TRP   A CZ2 1 
ATOM   372  C  CZ3 . TRP   A 1 57  ? 26.45719 -1.36637  22.29502  1.000 83.39701  ? 57  TRP   A CZ3 1 
ATOM   373  C  CH2 . TRP   A 1 57  ? 26.91763 -1.28819  23.61471  1.000 80.35069  ? 57  TRP   A CH2 1 
ATOM   374  N  N   . SER   A 1 58  ? 29.19676 0.85311   16.32008  1.000 87.67026  ? 58  SER   A N   1 
ATOM   375  C  CA  . SER   A 1 58  ? 29.12001 1.53712   15.03625  1.000 86.33914  ? 58  SER   A CA  1 
ATOM   376  C  C   . SER   A 1 58  ? 28.23019 2.76773   15.16145  1.000 91.58386  ? 58  SER   A C   1 
ATOM   377  O  O   . SER   A 1 58  ? 27.17611 2.72135   15.80198  1.000 98.40390  ? 58  SER   A O   1 
ATOM   378  C  CB  . SER   A 1 58  ? 28.57797 0.60661   13.94928  1.000 93.57512  ? 58  SER   A CB  1 
ATOM   379  O  OG  . SER   A 1 58  ? 28.50496 1.27089   12.69953  1.000 98.44906  ? 58  SER   A OG  1 
ATOM   380  N  N   . VAL   A 1 59  ? 28.65725 3.86816   14.54058  1.000 92.06487  ? 59  VAL   A N   1 
ATOM   381  C  CA  . VAL   A 1 59  ? 27.97599 5.15177   14.67651  1.000 99.53302  ? 59  VAL   A CA  1 
ATOM   382  C  C   . VAL   A 1 59  ? 27.03872 5.43469   13.50625  1.000 104.42646 ? 59  VAL   A C   1 
ATOM   383  O  O   . VAL   A 1 59  ? 26.57808 6.56955   13.34849  1.000 101.16765 ? 59  VAL   A O   1 
ATOM   384  C  CB  . VAL   A 1 59  ? 28.98706 6.29688   14.84648  1.000 96.96702  ? 59  VAL   A CB  1 
ATOM   385  C  CG1 . VAL   A 1 59  ? 29.88193 6.04088   16.04658  1.000 89.60061  ? 59  VAL   A CG1 1 
ATOM   386  C  CG2 . VAL   A 1 59  ? 29.81553 6.46595   13.58146  1.000 99.88263  ? 59  VAL   A CG2 1 
ATOM   387  N  N   . ASN   A 1 60  ? 26.73924 4.43214   12.68667  1.000 109.28813 ? 60  ASN   A N   1 
ATOM   388  C  CA  . ASN   A 1 60  ? 25.90533 4.64139   11.51216  1.000 111.46186 ? 60  ASN   A CA  1 
ATOM   389  C  C   . ASN   A 1 60  ? 24.43168 4.70217   11.89300  1.000 114.79636 ? 60  ASN   A C   1 
ATOM   390  O  O   . ASN   A 1 60  ? 23.97343 3.98018   12.78336  1.000 114.13421 ? 60  ASN   A O   1 
ATOM   391  C  CB  . ASN   A 1 60  ? 26.13023 3.52307   10.49425  1.000 110.49007 ? 60  ASN   A CB  1 
ATOM   392  C  CG  . ASN   A 1 60  ? 27.57304 3.42828   10.04109  1.000 106.19051 ? 60  ASN   A CG  1 
ATOM   393  O  OD1 . ASN   A 1 60  ? 28.46026 4.05707   10.61796  1.000 99.15413  ? 60  ASN   A OD1 1 
ATOM   394  N  ND2 . ASN   A 1 60  ? 27.81606 2.63419   9.00492   1.000 107.26825 ? 60  ASN   A ND2 1 
ATOM   395  N  N   . GLN   A 1 61  ? 23.68813 5.57749   11.21012  1.000 117.52257 ? 61  GLN   A N   1 
ATOM   396  C  CA  . GLN   A 1 61  ? 22.23658 5.58309   11.34690  1.000 121.85670 ? 61  GLN   A CA  1 
ATOM   397  C  C   . GLN   A 1 61  ? 21.60945 4.31575   10.78490  1.000 129.46952 ? 61  GLN   A C   1 
ATOM   398  O  O   . GLN   A 1 61  ? 20.49119 3.96337   11.17527  1.000 125.98544 ? 61  GLN   A O   1 
ATOM   399  C  CB  . GLN   A 1 61  ? 21.63667 6.80385   10.64540  1.000 121.51093 ? 61  GLN   A CB  1 
ATOM   400  C  CG  . GLN   A 1 61  ? 22.01474 8.14122   11.25846  1.000 114.85106 ? 61  GLN   A CG  1 
ATOM   401  C  CD  . GLN   A 1 61  ? 21.35734 9.30949   10.54772  1.000 125.30760 ? 61  GLN   A CD  1 
ATOM   402  O  OE1 . GLN   A 1 61  ? 20.75854 9.14653   9.48392   1.000 127.91825 ? 61  GLN   A OE1 1 
ATOM   403  N  NE2 . GLN   A 1 61  ? 21.46335 10.49594  11.13531  1.000 116.75361 ? 61  GLN   A NE2 1 
ATOM   404  N  N   . HIS   A 1 62  ? 22.30677 3.62688   9.87967   1.000 132.77296 ? 62  HIS   A N   1 
ATOM   405  C  CA  . HIS   A 1 62  ? 21.79516 2.40960   9.26517   1.000 136.99635 ? 62  HIS   A CA  1 
ATOM   406  C  C   . HIS   A 1 62  ? 21.75578 1.23356   10.23055  1.000 129.13821 ? 62  HIS   A C   1 
ATOM   407  O  O   . HIS   A 1 62  ? 21.11995 0.22059   9.91956   1.000 121.67671 ? 62  HIS   A O   1 
ATOM   408  C  CB  . HIS   A 1 62  ? 22.65081 2.04852   8.04935   1.000 143.30136 ? 62  HIS   A CB  1 
ATOM   409  C  CG  . HIS   A 1 62  ? 23.15227 3.23797   7.29017   1.000 142.82757 ? 62  HIS   A CG  1 
ATOM   410  N  ND1 . HIS   A 1 62  ? 24.47867 3.39921   6.95154   1.000 143.59152 ? 62  HIS   A ND1 1 
ATOM   411  C  CD2 . HIS   A 1 62  ? 22.50590 4.32471   6.80535   1.000 139.48735 ? 62  HIS   A CD2 1 
ATOM   412  C  CE1 . HIS   A 1 62  ? 24.62791 4.53389   6.29157   1.000 143.06379 ? 62  HIS   A CE1 1 
ATOM   413  N  NE2 . HIS   A 1 62  ? 23.44599 5.11458   6.18906   1.000 144.75883 ? 62  HIS   A NE2 1 
ATOM   414  N  N   . LYS   A 1 63  ? 22.41271 1.33976   11.38164  1.000 126.66931 ? 63  LYS   A N   1 
ATOM   415  C  CA  . LYS   A 1 63  ? 22.47243 0.24861   12.34158  1.000 125.75108 ? 63  LYS   A CA  1 
ATOM   416  C  C   . LYS   A 1 63  ? 21.33265 0.35486   13.34556  1.000 123.28060 ? 63  LYS   A C   1 
ATOM   417  O  O   . LYS   A 1 63  ? 21.01091 1.44418   13.82896  1.000 116.51298 ? 63  LYS   A O   1 
ATOM   418  C  CB  . LYS   A 1 63  ? 23.81392 0.25227   13.07681  1.000 114.08922 ? 63  LYS   A CB  1 
ATOM   419  C  CG  . LYS   A 1 63  ? 25.02614 0.21115   12.16157  1.000 109.45071 ? 63  LYS   A CG  1 
ATOM   420  C  CD  . LYS   A 1 63  ? 25.02191 -1.03463  11.29190  1.000 108.25983 ? 63  LYS   A CD  1 
ATOM   421  C  CE  . LYS   A 1 63  ? 26.22924 -1.06433  10.36932  1.000 109.72739 ? 63  LYS   A CE  1 
ATOM   422  N  NZ  . LYS   A 1 63  ? 26.22827 -2.26597  9.49052   1.000 105.99899 ? 63  LYS   A NZ  1 
ATOM   423  N  N   . GLN   A 1 64  ? 20.72233 -0.78859  13.65214  1.000 124.49501 ? 64  GLN   A N   1 
ATOM   424  C  CA  . GLN   A 1 64  ? 19.70161 -0.87431  14.68850  1.000 118.62815 ? 64  GLN   A CA  1 
ATOM   425  C  C   . GLN   A 1 64  ? 20.23341 -1.45506  15.98944  1.000 110.67652 ? 64  GLN   A C   1 
ATOM   426  O  O   . GLN   A 1 64  ? 19.79611 -1.03895  17.06703  1.000 112.05557 ? 64  GLN   A O   1 
ATOM   427  C  CB  . GLN   A 1 64  ? 18.51485 -1.71746  14.20446  1.000 123.38182 ? 64  GLN   A CB  1 
ATOM   428  C  CG  . GLN   A 1 64  ? 17.78939 -1.15056  12.98755  1.000 129.14722 ? 64  GLN   A CG  1 
ATOM   429  C  CD  . GLN   A 1 64  ? 18.52332 -1.41647  11.68534  1.000 122.97286 ? 64  GLN   A CD  1 
ATOM   430  O  OE1 . GLN   A 1 64  ? 19.43143 -2.24595  11.62991  1.000 120.18653 ? 64  GLN   A OE1 1 
ATOM   431  N  NE2 . GLN   A 1 64  ? 18.13444 -0.70887  10.63059  1.000 112.45263 ? 64  GLN   A NE2 1 
ATOM   432  N  N   . ASP   A 1 65  ? 21.16270 -2.40840  15.90888  1.000 103.38752 ? 65  ASP   A N   1 
ATOM   433  C  CA  . ASP   A 1 65  ? 21.90109 -2.92706  17.05930  1.000 97.12331  ? 65  ASP   A CA  1 
ATOM   434  C  C   . ASP   A 1 65  ? 23.37133 -2.63872  16.78655  1.000 92.97934  ? 65  ASP   A C   1 
ATOM   435  O  O   . ASP   A 1 65  ? 24.08412 -3.47762  16.21285  1.000 87.63529  ? 65  ASP   A O   1 
ATOM   436  C  CB  . ASP   A 1 65  ? 21.64492 -4.41907  17.26279  1.000 100.65327 ? 65  ASP   A CB  1 
ATOM   437  C  CG  . ASP   A 1 65  ? 22.17980 -4.92924  18.58728  1.000 95.83888  ? 65  ASP   A CG  1 
ATOM   438  O  OD1 . ASP   A 1 65  ? 22.72640 -4.11918  19.36513  1.000 97.03667  ? 65  ASP   A OD1 1 
ATOM   439  O  OD2 . ASP   A 1 65  ? 22.05003 -6.14342  18.85149  1.000 90.54583  ? 65  ASP   A OD2 1 
ATOM   440  N  N   . PRO   A 1 66  ? 23.86877 -1.46357  17.17691  1.000 94.04508  ? 66  PRO   A N   1 
ATOM   441  C  CA  . PRO   A 1 66  ? 25.19048 -1.02610  16.70718  1.000 90.00877  ? 66  PRO   A CA  1 
ATOM   442  C  C   . PRO   A 1 66  ? 26.36218 -1.63813  17.45954  1.000 82.68390  ? 66  PRO   A C   1 
ATOM   443  O  O   . PRO   A 1 66  ? 27.47926 -1.11933  17.37982  1.000 84.18733  ? 66  PRO   A O   1 
ATOM   444  C  CB  . PRO   A 1 66  ? 25.13654 0.49102   16.91471  1.000 87.60356  ? 66  PRO   A CB  1 
ATOM   445  C  CG  . PRO   A 1 66  ? 24.24293 0.65732   18.09663  1.000 85.33379  ? 66  PRO   A CG  1 
ATOM   446  C  CD  . PRO   A 1 66  ? 23.20731 -0.43900  18.00448  1.000 94.26843  ? 66  PRO   A CD  1 
ATOM   447  N  N   . TYR   A 1 67  ? 26.13363 -2.72915  18.18505  1.000 83.74497  ? 67  TYR   A N   1 
ATOM   448  C  CA  . TYR   A 1 67  ? 27.22034 -3.38641  18.89845  1.000 85.63063  ? 67  TYR   A CA  1 
ATOM   449  C  C   . TYR   A 1 67  ? 28.21510 -3.99004  17.91403  1.000 87.25358  ? 67  TYR   A C   1 
ATOM   450  O  O   . TYR   A 1 67  ? 27.83077 -4.62500  16.92786  1.000 97.06480  ? 67  TYR   A O   1 
ATOM   451  C  CB  . TYR   A 1 67  ? 26.66897 -4.47161  19.82520  1.000 87.47288  ? 67  TYR   A CB  1 
ATOM   452  C  CG  . TYR   A 1 67  ? 27.72986 -5.24094  20.58501  1.000 80.43942  ? 67  TYR   A CG  1 
ATOM   453  C  CD1 . TYR   A 1 67  ? 28.20318 -4.78644  21.80934  1.000 79.73005  ? 67  TYR   A CD1 1 
ATOM   454  C  CD2 . TYR   A 1 67  ? 28.25192 -6.42625  20.08095  1.000 83.79564  ? 67  TYR   A CD2 1 
ATOM   455  C  CE1 . TYR   A 1 67  ? 29.17039 -5.48758  22.50649  1.000 77.78669  ? 67  TYR   A CE1 1 
ATOM   456  C  CE2 . TYR   A 1 67  ? 29.21891 -7.13198  20.76958  1.000 81.45243  ? 67  TYR   A CE2 1 
ATOM   457  C  CZ  . TYR   A 1 67  ? 29.67361 -6.65926  21.98097  1.000 75.83676  ? 67  TYR   A CZ  1 
ATOM   458  O  OH  . TYR   A 1 67  ? 30.63490 -7.36362  22.66689  1.000 72.40742  ? 67  TYR   A OH  1 
ATOM   459  N  N   . ILE   A 1 68  ? 29.50428 -3.78595  18.18418  1.000 82.07287  ? 68  ILE   A N   1 
ATOM   460  C  CA  . ILE   A 1 68  ? 30.55329 -4.36326  17.35082  1.000 84.39682  ? 68  ILE   A CA  1 
ATOM   461  C  C   . ILE   A 1 68  ? 31.35966 -5.37093  18.15927  1.000 85.02027  ? 68  ILE   A C   1 
ATOM   462  O  O   . ILE   A 1 68  ? 31.40893 -6.55632  17.81178  1.000 88.65663  ? 68  ILE   A O   1 
ATOM   463  C  CB  . ILE   A 1 68  ? 31.47131 -3.28056  16.75260  1.000 79.79177  ? 68  ILE   A CB  1 
ATOM   464  C  CG1 . ILE   A 1 68  ? 30.71532 -2.44479  15.71808  1.000 87.41960  ? 68  ILE   A CG1 1 
ATOM   465  C  CG2 . ILE   A 1 68  ? 32.70849 -3.91375  16.13220  1.000 78.15249  ? 68  ILE   A CG2 1 
ATOM   466  C  CD1 . ILE   A 1 68  ? 31.59106 -1.45829  14.97324  1.000 85.84994  ? 68  ILE   A CD1 1 
ATOM   467  N  N   . ALA   A 1 69  ? 31.99358 -4.92089  19.24106  1.000 82.24833  ? 69  ALA   A N   1 
ATOM   468  C  CA  . ALA   A 1 69  ? 32.90508 -5.80861  19.95609  1.000 75.51352  ? 69  ALA   A CA  1 
ATOM   469  C  C   . ALA   A 1 69  ? 33.08603 -5.34470  21.39501  1.000 78.71412  ? 69  ALA   A C   1 
ATOM   470  O  O   . ALA   A 1 69  ? 32.68209 -4.24386  21.77523  1.000 81.32076  ? 69  ALA   A O   1 
ATOM   471  C  CB  . ALA   A 1 69  ? 34.26041 -5.89578  19.24653  1.000 76.46429  ? 69  ALA   A CB  1 
ATOM   472  N  N   . SER   A 1 70  ? 33.72466 -6.20768  22.18765  1.000 76.22320  ? 70  SER   A N   1 
ATOM   473  C  CA  . SER   A 1 70  ? 34.04264 -5.93054  23.58031  1.000 73.63304  ? 70  SER   A CA  1 
ATOM   474  C  C   . SER   A 1 70  ? 35.50549 -6.25461  23.85211  1.000 73.76896  ? 70  SER   A C   1 
ATOM   475  O  O   . SER   A 1 70  ? 36.09351 -7.13784  23.22166  1.000 67.62606  ? 70  SER   A O   1 
ATOM   476  C  CB  . SER   A 1 70  ? 33.15303 -6.73744  24.53877  1.000 66.87821  ? 70  SER   A CB  1 
ATOM   477  O  OG  . SER   A 1 70  ? 31.78608 -6.40394  24.37558  1.000 73.91648  ? 70  SER   A OG  1 
ATOM   478  N  N   . MET   A 1 71  ? 36.08474 -5.52497  24.80394  1.000 76.38044  ? 71  MET   A N   1 
ATOM   479  C  CA  . MET   A 1 71  ? 37.46047 -5.72231  25.25672  1.000 72.22304  ? 71  MET   A CA  1 
ATOM   480  C  C   . MET   A 1 71  ? 37.40400 -5.73482  26.78096  1.000 75.49362  ? 71  MET   A C   1 
ATOM   481  O  O   . MET   A 1 71  ? 37.24095 -4.68454  27.41069  1.000 76.67521  ? 71  MET   A O   1 
ATOM   482  C  CB  . MET   A 1 71  ? 38.37752 -4.62288  24.72903  1.000 76.31941  ? 71  MET   A CB  1 
ATOM   483  C  CG  . MET   A 1 71  ? 38.37153 -4.49220  23.21258  1.000 84.25370  ? 71  MET   A CG  1 
ATOM   484  S  SD  . MET   A 1 71  ? 38.54227 -2.79171  22.63222  1.000 84.40025  ? 71  MET   A SD  1 
ATOM   485  C  CE  . MET   A 1 71  ? 40.17383 -2.37889  23.23640  1.000 74.32956  ? 71  MET   A CE  1 
ATOM   486  N  N   . GLU   A 1 72  ? 37.53263 -6.92362  27.36985  1.000 75.33166  ? 72  GLU   A N   1 
ATOM   487  C  CA  . GLU   A 1 72  ? 37.18955 -7.14885  28.76884  1.000 78.50046  ? 72  GLU   A CA  1 
ATOM   488  C  C   . GLU   A 1 72  ? 38.39385 -7.57443  29.60306  1.000 76.82204  ? 72  GLU   A C   1 
ATOM   489  O  O   . GLU   A 1 72  ? 38.24014 -8.27050  30.60799  1.000 82.47993  ? 72  GLU   A O   1 
ATOM   490  C  CB  . GLU   A 1 72  ? 36.07918 -8.19342  28.87282  1.000 78.33617  ? 72  GLU   A CB  1 
ATOM   491  C  CG  . GLU   A 1 72  ? 34.88296 -7.90972  27.97915  1.000 82.99067  ? 72  GLU   A CG  1 
ATOM   492  C  CD  . GLU   A 1 72  ? 34.14277 -9.16937  27.57552  1.000 81.26182  ? 72  GLU   A CD  1 
ATOM   493  O  OE1 . GLU   A 1 72  ? 34.74730 -10.26111 27.63400  1.000 83.79132  ? 72  GLU   A OE1 1 
ATOM   494  O  OE2 . GLU   A 1 72  ? 32.95620 -9.06729  27.19855  1.000 72.81641  ? 72  GLU   A OE2 1 
ATOM   495  N  N   . HIS   A 1 73  ? 39.59825 -7.16078  29.21008  1.000 76.15914  ? 73  HIS   A N   1 
ATOM   496  C  CA  . HIS   A 1 73  ? 40.79115 -7.56386  29.94417  1.000 76.31530  ? 73  HIS   A CA  1 
ATOM   497  C  C   . HIS   A 1 73  ? 41.06020 -6.69805  31.16910  1.000 67.34913  ? 73  HIS   A C   1 
ATOM   498  O  O   . HIS   A 1 73  ? 41.98138 -7.00747  31.93187  1.000 67.58021  ? 73  HIS   A O   1 
ATOM   499  C  CB  . HIS   A 1 73  ? 42.01296 -7.54259  29.02100  1.000 74.78988  ? 73  HIS   A CB  1 
ATOM   500  C  CG  . HIS   A 1 73  ? 43.02416 -8.60181  29.33216  1.000 76.71745  ? 73  HIS   A CG  1 
ATOM   501  N  ND1 . HIS   A 1 73  ? 43.60889 -8.73204  30.57337  1.000 75.02389  ? 73  HIS   A ND1 1 
ATOM   502  C  CD2 . HIS   A 1 73  ? 43.55500 -9.58088  28.56176  1.000 78.33241  ? 73  HIS   A CD2 1 
ATOM   503  C  CE1 . HIS   A 1 73  ? 44.45478 -9.74669  30.55485  1.000 81.56939  ? 73  HIS   A CE1 1 
ATOM   504  N  NE2 . HIS   A 1 73  ? 44.44132 -10.27845 29.34583  1.000 82.56917  ? 73  HIS   A NE2 1 
ATOM   505  N  N   . HIS   A 1 74  ? 40.28602 -5.63682  31.38138  1.000 63.24815  ? 74  HIS   A N   1 
ATOM   506  C  CA  . HIS   A 1 74  ? 40.48945 -4.76888  32.53010  1.000 67.26526  ? 74  HIS   A CA  1 
ATOM   507  C  C   . HIS   A 1 74  ? 39.83221 -5.35695  33.77833  1.000 73.25828  ? 74  HIS   A C   1 
ATOM   508  O  O   . HIS   A 1 74  ? 39.07200 -6.32721  33.72102  1.000 73.23309  ? 74  HIS   A O   1 
ATOM   509  C  CB  . HIS   A 1 74  ? 39.94669 -3.36874  32.24758  1.000 64.63057  ? 74  HIS   A CB  1 
ATOM   510  C  CG  . HIS   A 1 74  ? 40.98954 -2.40048  31.78317  1.000 63.83453  ? 74  HIS   A CG  1 
ATOM   511  N  ND1 . HIS   A 1 74  ? 42.26710 -2.37950  32.29997  1.000 59.90442  ? 74  HIS   A ND1 1 
ATOM   512  C  CD2 . HIS   A 1 74  ? 40.94582 -1.42167  30.84851  1.000 68.41789  ? 74  HIS   A CD2 1 
ATOM   513  C  CE1 . HIS   A 1 74  ? 42.96484 -1.42850  31.70492  1.000 64.37194  ? 74  HIS   A CE1 1 
ATOM   514  N  NE2 . HIS   A 1 74  ? 42.18643 -0.83227  30.82006  1.000 67.70328  ? 74  HIS   A NE2 1 
ATOM   515  N  N   . THR   A 1 75  ? 40.13600 -4.74605  34.92348  1.000 77.44063  ? 75  THR   A N   1 
ATOM   516  C  CA  . THR   A 1 75  ? 39.66946 -5.21273  36.22378  1.000 77.02286  ? 75  THR   A CA  1 
ATOM   517  C  C   . THR   A 1 75  ? 38.72760 -4.23307  36.90786  1.000 84.10239  ? 75  THR   A C   1 
ATOM   518  O  O   . THR   A 1 75  ? 37.64160 -4.62555  37.34631  1.000 87.19125  ? 75  THR   A O   1 
ATOM   519  C  CB  . THR   A 1 75  ? 40.86960 -5.49856  37.13982  1.000 65.25280  ? 75  THR   A CB  1 
ATOM   520  O  OG1 . THR   A 1 75  ? 41.64598 -6.57156  36.59293  1.000 67.20466  ? 75  THR   A OG1 1 
ATOM   521  C  CG2 . THR   A 1 75  ? 40.40046 -5.87656  38.53818  1.000 59.80033  ? 75  THR   A CG2 1 
ATOM   522  N  N   . ASP   A 1 76  ? 39.11121 -2.96073  37.01222  1.000 85.04249  ? 76  ASP   A N   1 
ATOM   523  C  CA  . ASP   A 1 76  ? 38.31069 -1.94966  37.68413  1.000 78.16710  ? 76  ASP   A CA  1 
ATOM   524  C  C   . ASP   A 1 76  ? 37.78903 -0.93373  36.66121  1.000 76.96375  ? 76  ASP   A C   1 
ATOM   525  O  O   . ASP   A 1 76  ? 37.66705 -1.24419  35.46722  1.000 78.55020  ? 76  ASP   A O   1 
ATOM   526  C  CB  . ASP   A 1 76  ? 39.14964 -1.30347  38.79175  1.000 72.60399  ? 76  ASP   A CB  1 
ATOM   527  C  CG  . ASP   A 1 76  ? 38.29910 -0.71848  39.90523  1.000 68.98831  ? 76  ASP   A CG  1 
ATOM   528  O  OD1 . ASP   A 1 76  ? 37.14611 -0.32156  39.63225  1.000 64.92380  ? 76  ASP   A OD1 1 
ATOM   529  O  OD2 . ASP   A 1 76  ? 38.78491 -0.65701  41.05425  1.000 73.60876  ? 76  ASP   A OD2 1 
ATOM   530  N  N   . TRP   A 1 77  ? 37.47510 0.27377   37.13272  1.000 76.43478  ? 77  TRP   A N   1 
ATOM   531  C  CA  . TRP   A 1 77  ? 36.98957 1.33242   36.25596  1.000 75.76824  ? 77  TRP   A CA  1 
ATOM   532  C  C   . TRP   A 1 77  ? 37.96533 1.58133   35.11302  1.000 75.10798  ? 77  TRP   A C   1 
ATOM   533  O  O   . TRP   A 1 77  ? 39.17975 1.44520   35.26568  1.000 74.33377  ? 77  TRP   A O   1 
ATOM   534  C  CB  . TRP   A 1 77  ? 36.79437 2.63352   37.03752  1.000 78.25567  ? 77  TRP   A CB  1 
ATOM   535  C  CG  . TRP   A 1 77  ? 35.56820 2.68862   37.88835  1.000 74.82108  ? 77  TRP   A CG  1 
ATOM   536  C  CD1 . TRP   A 1 77  ? 34.76115 1.64823   38.23865  1.000 71.90787  ? 77  TRP   A CD1 1 
ATOM   537  C  CD2 . TRP   A 1 77  ? 35.00331 3.85757   38.49394  1.000 72.36243  ? 77  TRP   A CD2 1 
ATOM   538  N  NE1 . TRP   A 1 77  ? 33.72952 2.09515   39.02937  1.000 65.49619  ? 77  TRP   A NE1 1 
ATOM   539  C  CE2 . TRP   A 1 77  ? 33.85572 3.44868   39.20015  1.000 67.34758  ? 77  TRP   A CE2 1 
ATOM   540  C  CE3 . TRP   A 1 77  ? 35.35846 5.21049   38.50830  1.000 70.37123  ? 77  TRP   A CE3 1 
ATOM   541  C  CZ2 . TRP   A 1 77  ? 33.06015 4.34316   39.91337  1.000 70.57098  ? 77  TRP   A CZ2 1 
ATOM   542  C  CZ3 . TRP   A 1 77  ? 34.56794 6.09677   39.21653  1.000 71.89154  ? 77  TRP   A CZ3 1 
ATOM   543  C  CH2 . TRP   A 1 77  ? 33.43220 5.65979   39.90922  1.000 72.08148  ? 77  TRP   A CH2 1 
ATOM   544  N  N   . VAL   A 1 78  ? 37.42094 1.95108   33.95794  1.000 72.60970  ? 78  VAL   A N   1 
ATOM   545  C  CA  . VAL   A 1 78  ? 38.20973 2.38457   32.81010  1.000 71.37562  ? 78  VAL   A CA  1 
ATOM   546  C  C   . VAL   A 1 78  ? 37.95660 3.87602   32.64219  1.000 79.36228  ? 78  VAL   A C   1 
ATOM   547  O  O   . VAL   A 1 78  ? 36.84781 4.28978   32.28174  1.000 81.29133  ? 78  VAL   A O   1 
ATOM   548  C  CB  . VAL   A 1 78  ? 37.85248 1.60655   31.53699  1.000 65.14509  ? 78  VAL   A CB  1 
ATOM   549  C  CG1 . VAL   A 1 78  ? 38.84386 1.92299   30.42670  1.000 63.03762  ? 78  VAL   A CG1 1 
ATOM   550  C  CG2 . VAL   A 1 78  ? 37.82310 0.11443   31.81963  1.000 72.58647  ? 78  VAL   A CG2 1 
ATOM   551  N  N   . ASN   A 1 79  ? 38.98092 4.68704   32.90197  1.000 74.79019  ? 79  ASN   A N   1 
ATOM   552  C  CA  . ASN   A 1 79  ? 38.80907 6.12957   33.01596  1.000 63.71597  ? 79  ASN   A CA  1 
ATOM   553  C  C   . ASN   A 1 79  ? 39.12169 6.89449   31.73801  1.000 64.71796  ? 79  ASN   A C   1 
ATOM   554  O  O   . ASN   A 1 79  ? 38.48859 7.92408   31.48293  1.000 67.90363  ? 79  ASN   A O   1 
ATOM   555  C  CB  . ASN   A 1 79  ? 39.68187 6.67278   34.15259  1.000 64.05410  ? 79  ASN   A CB  1 
ATOM   556  C  CG  . ASN   A 1 79  ? 39.26795 6.13613   35.50957  1.000 64.11945  ? 79  ASN   A CG  1 
ATOM   557  O  OD1 . ASN   A 1 79  ? 38.50244 6.77237   36.23403  1.000 62.43223  ? 79  ASN   A OD1 1 
ATOM   558  N  ND2 . ASN   A 1 79  ? 39.76774 4.95569   35.85745  1.000 63.40305  ? 79  ASN   A ND2 1 
ATOM   559  N  N   . ASP   A 1 80  ? 40.07409 6.43359   30.92953  1.000 65.70853  ? 80  ASP   A N   1 
ATOM   560  C  CA  . ASP   A 1 80  ? 40.44672 7.16821   29.72958  1.000 68.85769  ? 80  ASP   A CA  1 
ATOM   561  C  C   . ASP   A 1 80  ? 40.97317 6.20181   28.67925  1.000 68.75669  ? 80  ASP   A C   1 
ATOM   562  O  O   . ASP   A 1 80  ? 41.61150 5.19632   29.00185  1.000 70.97577  ? 80  ASP   A O   1 
ATOM   563  C  CB  . ASP   A 1 80  ? 41.49517 8.24513   30.03581  1.000 68.86190  ? 80  ASP   A CB  1 
ATOM   564  C  CG  . ASP   A 1 80  ? 41.41236 9.42671   29.08787  1.000 70.26680  ? 80  ASP   A CG  1 
ATOM   565  O  OD1 . ASP   A 1 80  ? 40.98732 9.23784   27.92828  1.000 73.67339  ? 80  ASP   A OD1 1 
ATOM   566  O  OD2 . ASP   A 1 80  ? 41.76874 10.54803  29.50613  1.000 71.27694  ? 80  ASP   A OD2 1 
ATOM   567  N  N   . ILE   A 1 81  ? 40.69592 6.52102   27.41504  1.000 68.84061  ? 81  ILE   A N   1 
ATOM   568  C  CA  . ILE   A 1 81  ? 41.15185 5.72869   26.28031  1.000 69.12877  ? 81  ILE   A CA  1 
ATOM   569  C  C   . ILE   A 1 81  ? 41.65511 6.67247   25.19635  1.000 73.20489  ? 81  ILE   A C   1 
ATOM   570  O  O   . ILE   A 1 81  ? 41.25235 7.83730   25.12609  1.000 73.34090  ? 81  ILE   A O   1 
ATOM   571  C  CB  . ILE   A 1 81  ? 40.03782 4.80686   25.73665  1.000 70.13086  ? 81  ILE   A CB  1 
ATOM   572  C  CG1 . ILE   A 1 81  ? 38.73610 5.58971   25.55286  1.000 71.73627  ? 81  ILE   A CG1 1 
ATOM   573  C  CG2 . ILE   A 1 81  ? 39.82765 3.61789   26.66412  1.000 68.42685  ? 81  ILE   A CG2 1 
ATOM   574  C  CD1 . ILE   A 1 81  ? 37.58741 4.74953   25.04393  1.000 71.07214  ? 81  ILE   A CD1 1 
ATOM   575  N  N   . VAL   A 1 82  ? 42.54402 6.16211   24.34503  1.000 75.35444  ? 82  VAL   A N   1 
ATOM   576  C  CA  . VAL   A 1 82  ? 43.19610 6.95630   23.30724  1.000 73.25660  ? 82  VAL   A CA  1 
ATOM   577  C  C   . VAL   A 1 82  ? 43.36053 6.09900   22.05949  1.000 77.60173  ? 82  VAL   A C   1 
ATOM   578  O  O   . VAL   A 1 82  ? 43.88331 4.98222   22.13327  1.000 78.75123  ? 82  VAL   A O   1 
ATOM   579  C  CB  . VAL   A 1 82  ? 44.56757 7.48807   23.77135  1.000 73.61622  ? 82  VAL   A CB  1 
ATOM   580  C  CG1 . VAL   A 1 82  ? 45.39940 7.92021   22.57841  1.000 79.32510  ? 82  VAL   A CG1 1 
ATOM   581  C  CG2 . VAL   A 1 82  ? 44.39634 8.64279   24.74722  1.000 75.18226  ? 82  VAL   A CG2 1 
ATOM   582  N  N   . LEU   A 1 83  ? 42.91688 6.61781   20.91740  1.000 78.31421  ? 83  LEU   A N   1 
ATOM   583  C  CA  . LEU   A 1 83  ? 43.14438 5.97406   19.63169  1.000 83.56327  ? 83  LEU   A CA  1 
ATOM   584  C  C   . LEU   A 1 83  ? 44.45631 6.45793   19.02385  1.000 84.22444  ? 83  LEU   A C   1 
ATOM   585  O  O   . LEU   A 1 83  ? 44.85999 7.60955   19.20647  1.000 91.04775  ? 83  LEU   A O   1 
ATOM   586  C  CB  . LEU   A 1 83  ? 41.98845 6.25587   18.67025  1.000 81.48792  ? 83  LEU   A CB  1 
ATOM   587  C  CG  . LEU   A 1 83  ? 40.71556 5.42905   18.85771  1.000 74.92328  ? 83  LEU   A CG  1 
ATOM   588  C  CD1 . LEU   A 1 83  ? 39.59974 5.95906   17.97195  1.000 71.74083  ? 83  LEU   A CD1 1 
ATOM   589  C  CD2 . LEU   A 1 83  ? 40.98811 3.96405   18.55515  1.000 79.54514  ? 83  LEU   A CD2 1 
ATOM   590  N  N   . CYS   A 1 84  ? 45.12192 5.56431   18.29253  1.000 84.45506  ? 84  CYS   A N   1 
ATOM   591  C  CA  . CYS   A 1 84  ? 46.43019 5.85986   17.72673  1.000 83.85930  ? 84  CYS   A CA  1 
ATOM   592  C  C   . CYS   A 1 84  ? 46.57376 5.21024   16.35865  1.000 88.30747  ? 84  CYS   A C   1 
ATOM   593  O  O   . CYS   A 1 84  ? 45.93015 4.20039   16.06068  1.000 88.25537  ? 84  CYS   A O   1 
ATOM   594  C  CB  . CYS   A 1 84  ? 47.56554 5.37075   18.63709  1.000 83.46387  ? 84  CYS   A CB  1 
ATOM   595  S  SG  . CYS   A 1 84  ? 47.53543 6.02768   20.31672  1.000 85.95611  ? 84  CYS   A SG  1 
ATOM   596  N  N   . CYS   A 1 85  ? 47.43448 5.80881   15.53268  1.000 93.77710  ? 85  CYS   A N   1 
ATOM   597  C  CA  . CYS   A 1 85  ? 47.85529 5.24345   14.25033  1.000 99.46150  ? 85  CYS   A CA  1 
ATOM   598  C  C   . CYS   A 1 85  ? 46.65436 4.94394   13.34899  1.000 104.61175 ? 85  CYS   A C   1 
ATOM   599  O  O   . CYS   A 1 85  ? 46.38894 3.79856   12.97898  1.000 103.28211 ? 85  CYS   A O   1 
ATOM   600  C  CB  . CYS   A 1 85  ? 48.71078 3.99066   14.47033  1.000 95.81234  ? 85  CYS   A CB  1 
ATOM   601  S  SG  . CYS   A 1 85  ? 50.15680 4.24438   15.53181  1.000 100.72822 ? 85  CYS   A SG  1 
ATOM   602  N  N   . ASN   A 1 86  ? 45.93142 6.01023   12.99606  1.000 108.13180 ? 86  ASN   A N   1 
ATOM   603  C  CA  . ASN   A 1 86  ? 44.73156 5.92357   12.15815  1.000 109.96855 ? 86  ASN   A CA  1 
ATOM   604  C  C   . ASN   A 1 86  ? 43.70675 4.94457   12.72733  1.000 101.30149 ? 86  ASN   A C   1 
ATOM   605  O  O   . ASN   A 1 86  ? 42.93015 4.34159   11.98143  1.000 94.51533  ? 86  ASN   A O   1 
ATOM   606  C  CB  . ASN   A 1 86  ? 45.07814 5.54106   10.71405  1.000 109.24571 ? 86  ASN   A CB  1 
ATOM   607  C  CG  . ASN   A 1 86  ? 45.98726 6.55250   10.04064  1.000 110.99021 ? 86  ASN   A CG  1 
ATOM   608  O  OD1 . ASN   A 1 86  ? 47.19887 6.55830   10.26011  1.000 113.39693 ? 86  ASN   A OD1 1 
ATOM   609  N  ND2 . ASN   A 1 86  ? 45.40602 7.41010   9.20863   1.000 109.31581 ? 86  ASN   A ND2 1 
ATOM   610  N  N   . GLY   A 1 87  ? 43.69741 4.77055   14.04764  1.000 92.59218  ? 87  GLY   A N   1 
ATOM   611  C  CA  . GLY   A 1 87  ? 42.75815 3.85838   14.66664  1.000 89.14949  ? 87  GLY   A CA  1 
ATOM   612  C  C   . GLY   A 1 87  ? 43.21997 2.42307   14.75562  1.000 96.69365  ? 87  GLY   A C   1 
ATOM   613  O  O   . GLY   A 1 87  ? 42.38516 1.52811   14.91553  1.000 100.89626 ? 87  GLY   A O   1 
ATOM   614  N  N   . LYS   A 1 88  ? 44.52666 2.17007   14.66139  1.000 94.38885  ? 88  LYS   A N   1 
ATOM   615  C  CA  . LYS   A 1 88  ? 45.04614 0.80904   14.73571  1.000 93.19150  ? 88  LYS   A CA  1 
ATOM   616  C  C   . LYS   A 1 88  ? 45.28929 0.35110   16.16957  1.000 89.16751  ? 88  LYS   A C   1 
ATOM   617  O  O   . LYS   A 1 88  ? 45.05425 -0.81853  16.49098  1.000 93.07356  ? 88  LYS   A O   1 
ATOM   618  C  CB  . LYS   A 1 88  ? 46.34253 0.69088   13.92729  1.000 95.88349  ? 88  LYS   A CB  1 
ATOM   619  C  CG  . LYS   A 1 88  ? 46.13506 0.64383   12.42076  1.000 105.12625 ? 88  LYS   A CG  1 
ATOM   620  C  CD  . LYS   A 1 88  ? 47.43468 0.34387   11.68739  1.000 108.10392 ? 88  LYS   A CD  1 
ATOM   621  C  CE  . LYS   A 1 88  ? 48.46477 1.43902   11.90785  1.000 95.97195  ? 88  LYS   A CE  1 
ATOM   622  N  NZ  . LYS   A 1 88  ? 49.73466 1.16346   11.17989  1.000 82.15912  ? 88  LYS   A NZ  1 
ATOM   623  N  N   . THR   A 1 89  ? 45.75550 1.24399   17.03863  1.000 85.61445  ? 89  THR   A N   1 
ATOM   624  C  CA  . THR   A 1 89  ? 46.08803 0.90335   18.41318  1.000 86.84284  ? 89  THR   A CA  1 
ATOM   625  C  C   . THR   A 1 89  ? 45.24949 1.73794   19.37227  1.000 83.07460  ? 89  THR   A C   1 
ATOM   626  O  O   . THR   A 1 89  ? 44.85718 2.86582   19.05757  1.000 83.82267  ? 89  THR   A O   1 
ATOM   627  C  CB  . THR   A 1 89  ? 47.58131 1.13363   18.69444  1.000 88.62665  ? 89  THR   A CB  1 
ATOM   628  O  OG1 . THR   A 1 89  ? 48.35884 0.64339   17.59468  1.000 85.19298  ? 89  THR   A OG1 1 
ATOM   629  C  CG2 . THR   A 1 89  ? 48.00695 0.41149   19.96407  1.000 98.18885  ? 89  THR   A CG2 1 
ATOM   630  N  N   . LEU   A 1 90  ? 44.97198 1.17464   20.54793  1.000 84.43172  ? 90  LEU   A N   1 
ATOM   631  C  CA  . LEU   A 1 90  ? 44.27275 1.89138   21.60243  1.000 79.33198  ? 90  LEU   A CA  1 
ATOM   632  C  C   . LEU   A 1 90  ? 45.02535 1.72009   22.91437  1.000 76.90168  ? 90  LEU   A C   1 
ATOM   633  O  O   . LEU   A 1 90  ? 45.64618 0.68413   23.16210  1.000 76.94817  ? 90  LEU   A O   1 
ATOM   634  C  CB  . LEU   A 1 90  ? 42.82129 1.40573   21.75180  1.000 79.39398  ? 90  LEU   A CB  1 
ATOM   635  C  CG  . LEU   A 1 90  ? 41.91288 2.22865   22.67040  1.000 69.05393  ? 90  LEU   A CG  1 
ATOM   636  C  CD1 . LEU   A 1 90  ? 40.60317 2.56689   21.97599  1.000 67.82423  ? 90  LEU   A CD1 1 
ATOM   637  C  CD2 . LEU   A 1 90  ? 41.65154 1.49152   23.97487  1.000 66.96488  ? 90  LEU   A CD2 1 
ATOM   638  N  N   . ILE   A 1 91  ? 44.98303 2.75711   23.74677  1.000 76.12672  ? 91  ILE   A N   1 
ATOM   639  C  CA  . ILE   A 1 91  ? 45.61790 2.74353   25.05922  1.000 74.41068  ? 91  ILE   A CA  1 
ATOM   640  C  C   . ILE   A 1 91  ? 44.58069 3.16805   26.08791  1.000 76.32289  ? 91  ILE   A C   1 
ATOM   641  O  O   . ILE   A 1 91  ? 43.92003 4.19861   25.91918  1.000 77.27339  ? 91  ILE   A O   1 
ATOM   642  C  CB  . ILE   A 1 91  ? 46.85439 3.66304   25.11719  1.000 75.48090  ? 91  ILE   A CB  1 
ATOM   643  C  CG1 . ILE   A 1 91  ? 48.00656 3.07956   24.29215  1.000 80.95933  ? 91  ILE   A CG1 1 
ATOM   644  C  CG2 . ILE   A 1 91  ? 47.29674 3.87671   26.55664  1.000 69.51731  ? 91  ILE   A CG2 1 
ATOM   645  C  CD1 . ILE   A 1 91  ? 47.99533 3.47612   22.82990  1.000 85.02816  ? 91  ILE   A CD1 1 
ATOM   646  N  N   . SER   A 1 92  ? 44.43904 2.37716   27.14835  1.000 79.21833  ? 92  SER   A N   1 
ATOM   647  C  CA  . SER   A 1 92  ? 43.40429 2.57761   28.15072  1.000 77.36638  ? 92  SER   A CA  1 
ATOM   648  C  C   . SER   A 1 92  ? 44.01971 2.72469   29.53416  1.000 69.40173  ? 92  SER   A C   1 
ATOM   649  O  O   . SER   A 1 92  ? 44.93183 1.97729   29.90391  1.000 69.59887  ? 92  SER   A O   1 
ATOM   650  C  CB  . SER   A 1 92  ? 42.41365 1.41223   28.15553  1.000 77.11756  ? 92  SER   A CB  1 
ATOM   651  O  OG  . SER   A 1 92  ? 43.05413 0.19943   28.51344  1.000 71.97399  ? 92  SER   A OG  1 
ATOM   652  N  N   . ALA   A 1 93  ? 43.50688 3.68993   30.29184  1.000 65.35122  ? 93  ALA   A N   1 
ATOM   653  C  CA  . ALA   A 1 93  ? 43.85685 3.87895   31.69130  1.000 67.94759  ? 93  ALA   A CA  1 
ATOM   654  C  C   . ALA   A 1 93  ? 42.72891 3.34891   32.56426  1.000 64.67624  ? 93  ALA   A C   1 
ATOM   655  O  O   . ALA   A 1 93  ? 41.55005 3.53190   32.24852  1.000 61.81344  ? 93  ALA   A O   1 
ATOM   656  C  CB  . ALA   A 1 93  ? 44.10778 5.35538   32.00071  1.000 67.82444  ? 93  ALA   A CB  1 
ATOM   657  N  N   . SER   A 1 94  ? 43.08987 2.69772   33.66674  1.000 65.75914  ? 94  SER   A N   1 
ATOM   658  C  CA  . SER   A 1 94  ? 42.09704 2.05336   34.51090  1.000 66.30588  ? 94  SER   A CA  1 
ATOM   659  C  C   . SER   A 1 94  ? 42.42478 2.27630   35.97954  1.000 68.18672  ? 94  SER   A C   1 
ATOM   660  O  O   . SER   A 1 94  ? 43.54411 2.64541   36.34280  1.000 69.50588  ? 94  SER   A O   1 
ATOM   661  C  CB  . SER   A 1 94  ? 42.00170 0.55157   34.21715  1.000 70.64357  ? 94  SER   A CB  1 
ATOM   662  O  OG  . SER   A 1 94  ? 41.07072 -0.07849  35.07984  1.000 68.77604  ? 94  SER   A OG  1 
ATOM   663  N  N   . SER   A 1 95  ? 41.41987 2.04096   36.82399  1.000 72.82684  ? 95  SER   A N   1 
ATOM   664  C  CA  . SER   A 1 95  ? 41.56828 2.15031   38.26934  1.000 75.24031  ? 95  SER   A CA  1 
ATOM   665  C  C   . SER   A 1 95  ? 42.25345 0.93978   38.88815  1.000 78.15231  ? 95  SER   A C   1 
ATOM   666  O  O   . SER   A 1 95  ? 42.49264 0.93819   40.10053  1.000 83.36534  ? 95  SER   A O   1 
ATOM   667  C  CB  . SER   A 1 95  ? 40.20057 2.35810   38.92714  1.000 72.24193  ? 95  SER   A CB  1 
ATOM   668  O  OG  . SER   A 1 95  ? 39.63354 3.60039   38.54816  1.000 75.94214  ? 95  SER   A OG  1 
ATOM   669  N  N   . ASP   A 1 96  ? 42.56916 -0.08581  38.09659  1.000 75.43602  ? 96  ASP   A N   1 
ATOM   670  C  CA  . ASP   A 1 96  ? 43.32304 -1.23469  38.57920  1.000 71.11438  ? 96  ASP   A CA  1 
ATOM   671  C  C   . ASP   A 1 96  ? 44.82855 -0.98961  38.58145  1.000 73.93311  ? 96  ASP   A C   1 
ATOM   672  O  O   . ASP   A 1 96  ? 45.60146 -1.95559  38.60252  1.000 77.12679  ? 96  ASP   A O   1 
ATOM   673  C  CB  . ASP   A 1 96  ? 42.98565 -2.47670  37.74689  1.000 75.60606  ? 96  ASP   A CB  1 
ATOM   674  C  CG  . ASP   A 1 96  ? 43.22636 -2.27554  36.25897  1.000 76.52105  ? 96  ASP   A CG  1 
ATOM   675  O  OD1 . ASP   A 1 96  ? 43.88020 -1.28230  35.87826  1.000 72.73438  ? 96  ASP   A OD1 1 
ATOM   676  O  OD2 . ASP   A 1 96  ? 42.75681 -3.11712  35.46390  1.000 74.12457  ? 96  ASP   A OD2 1 
ATOM   677  N  N   . THR   A 1 97  ? 45.24228 0.28066   38.55092  1.000 80.03233  ? 97  THR   A N   1 
ATOM   678  C  CA  . THR   A 1 97  ? 46.65049 0.68429   38.57222  1.000 80.24276  ? 97  THR   A CA  1 
ATOM   679  C  C   . THR   A 1 97  ? 47.41874 0.15158   37.36451  1.000 77.76791  ? 97  THR   A C   1 
ATOM   680  O  O   . THR   A 1 97  ? 48.62768 -0.08074  37.44031  1.000 81.86690  ? 97  THR   A O   1 
ATOM   681  C  CB  . THR   A 1 97  ? 47.34256 0.25521   39.87235  1.000 88.15191  ? 97  THR   A CB  1 
ATOM   682  O  OG1 . THR   A 1 97  ? 47.54298 -1.16379  39.86724  1.000 94.55419  ? 97  THR   A OG1 1 
ATOM   683  C  CG2 . THR   A 1 97  ? 46.49714 0.63532   41.08273  1.000 88.01049  ? 97  THR   A CG2 1 
ATOM   684  N  N   . THR   A 1 98  ? 46.73273 -0.04117  36.23860  1.000 74.47924  ? 98  THR   A N   1 
ATOM   685  C  CA  . THR   A 1 98  ? 47.35997 -0.53890  35.02298  1.000 78.95675  ? 98  THR   A CA  1 
ATOM   686  C  C   . THR   A 1 98  ? 47.00800 0.36207   33.84754  1.000 75.19810  ? 98  THR   A C   1 
ATOM   687  O  O   . THR   A 1 98  ? 45.98350 1.04949   33.84511  1.000 68.56243  ? 98  THR   A O   1 
ATOM   688  C  CB  . THR   A 1 98  ? 46.93273 -1.98011  34.69753  1.000 72.45844  ? 98  THR   A CB  1 
ATOM   689  O  OG1 . THR   A 1 98  ? 45.54609 -2.00064  34.33687  1.000 64.29607  ? 98  THR   A OG1 1 
ATOM   690  C  CG2 . THR   A 1 98  ? 47.15984 -2.89719  35.89046  1.000 80.98324  ? 98  THR   A CG2 1 
ATOM   691  N  N   . VAL   A 1 99  ? 47.88039 0.34738   32.84293  1.000 78.27756  ? 99  VAL   A N   1 
ATOM   692  C  CA  . VAL   A 1 99  ? 47.65151 1.02533   31.57107  1.000 75.95240  ? 99  VAL   A CA  1 
ATOM   693  C  C   . VAL   A 1 99  ? 47.79200 -0.02875  30.48346  1.000 81.93722  ? 99  VAL   A C   1 
ATOM   694  O  O   . VAL   A 1 99  ? 48.88705 -0.55800  30.26268  1.000 86.07439  ? 99  VAL   A O   1 
ATOM   695  C  CB  . VAL   A 1 99  ? 48.62974 2.18534   31.34448  1.000 78.56986  ? 99  VAL   A CB  1 
ATOM   696  C  CG1 . VAL   A 1 99  ? 48.27684 2.93343   30.06716  1.000 82.04857  ? 99  VAL   A CG1 1 
ATOM   697  C  CG2 . VAL   A 1 99  ? 48.62942 3.12444   32.53844  1.000 79.06512  ? 99  VAL   A CG2 1 
ATOM   698  N  N   . LYS   A 1 100 ? 46.69609 -0.34110  29.80539  1.000 77.77472  ? 100 LYS   A N   1 
ATOM   699  C  CA  . LYS   A 1 100 ? 46.68622 -1.44607  28.85736  1.000 78.23965  ? 100 LYS   A CA  1 
ATOM   700  C  C   . LYS   A 1 100 ? 46.76281 -0.94305  27.42181  1.000 76.46651  ? 100 LYS   A C   1 
ATOM   701  O  O   . LYS   A 1 100 ? 46.20607 0.10463   27.08376  1.000 78.93822  ? 100 LYS   A O   1 
ATOM   702  C  CB  . LYS   A 1 100 ? 45.44399 -2.31776  29.04850  1.000 79.16729  ? 100 LYS   A CB  1 
ATOM   703  C  CG  . LYS   A 1 100 ? 45.53174 -3.23328  30.26046  1.000 76.32167  ? 100 LYS   A CG  1 
ATOM   704  C  CD  . LYS   A 1 100 ? 44.35380 -4.18894  30.32912  1.000 78.31504  ? 100 LYS   A CD  1 
ATOM   705  C  CE  . LYS   A 1 100 ? 44.43849 -5.07602  31.55913  1.000 79.36136  ? 100 LYS   A CE  1 
ATOM   706  N  NZ  . LYS   A 1 100 ? 45.55826 -6.05157  31.47097  1.000 77.48571  ? 100 LYS   A NZ  1 
ATOM   707  N  N   . VAL   A 1 101 ? 47.46794 -1.69938  26.58517  1.000 77.17389  ? 101 VAL   A N   1 
ATOM   708  C  CA  . VAL   A 1 101 ? 47.62975 -1.40420  25.16664  1.000 83.06512  ? 101 VAL   A CA  1 
ATOM   709  C  C   . VAL   A 1 101 ? 46.95006 -2.52075  24.38900  1.000 81.78450  ? 101 VAL   A C   1 
ATOM   710  O  O   . VAL   A 1 101 ? 47.27223 -3.70120  24.58136  1.000 89.52670  ? 101 VAL   A O   1 
ATOM   711  C  CB  . VAL   A 1 101 ? 49.11081 -1.28047  24.77773  1.000 91.45794  ? 101 VAL   A CB  1 
ATOM   712  C  CG1 . VAL   A 1 101 ? 49.24518 -0.84712  23.32524  1.000 95.74659  ? 101 VAL   A CG1 1 
ATOM   713  C  CG2 . VAL   A 1 101 ? 49.82431 -0.30908  25.70552  1.000 90.71463  ? 101 VAL   A CG2 1 
ATOM   714  N  N   . TRP   A 1 102 ? 46.02068 -2.14502  23.50911  1.000 80.19345  ? 102 TRP   A N   1 
ATOM   715  C  CA  . TRP   A 1 102 ? 45.17596 -3.07810  22.78225  1.000 86.39802  ? 102 TRP   A CA  1 
ATOM   716  C  C   . TRP   A 1 102 ? 45.25338 -2.79738  21.28803  1.000 87.06357  ? 102 TRP   A C   1 
ATOM   717  O  O   . TRP   A 1 102 ? 45.55501 -1.68091  20.85364  1.000 85.75858  ? 102 TRP   A O   1 
ATOM   718  C  CB  . TRP   A 1 102 ? 43.69754 -2.98239  23.20406  1.000 80.32429  ? 102 TRP   A CB  1 
ATOM   719  C  CG  . TRP   A 1 102 ? 43.42319 -2.65088  24.64560  1.000 74.02102  ? 102 TRP   A CG  1 
ATOM   720  C  CD1 . TRP   A 1 102 ? 43.81742 -1.53368  25.32703  1.000 74.09702  ? 102 TRP   A CD1 1 
ATOM   721  C  CD2 . TRP   A 1 102 ? 42.63675 -3.42005  25.56285  1.000 73.73574  ? 102 TRP   A CD2 1 
ATOM   722  N  NE1 . TRP   A 1 102 ? 43.35209 -1.57706  26.61769  1.000 73.72693  ? 102 TRP   A NE1 1 
ATOM   723  C  CE2 . TRP   A 1 102 ? 42.62227 -2.72382  26.78754  1.000 75.96131  ? 102 TRP   A CE2 1 
ATOM   724  C  CE3 . TRP   A 1 102 ? 41.95390 -4.63638  25.47070  1.000 74.63743  ? 102 TRP   A CE3 1 
ATOM   725  C  CZ2 . TRP   A 1 102 ? 41.95302 -3.20370  27.91039  1.000 77.89454  ? 102 TRP   A CZ2 1 
ATOM   726  C  CZ3 . TRP   A 1 102 ? 41.29237 -5.11151  26.58665  1.000 72.64471  ? 102 TRP   A CZ3 1 
ATOM   727  C  CH2 . TRP   A 1 102 ? 41.29493 -4.39572  27.78975  1.000 73.19519  ? 102 TRP   A CH2 1 
ATOM   728  N  N   . ASN   A 1 103 ? 44.94429 -3.82822  20.50551  1.000 88.57028  ? 103 ASN   A N   1 
ATOM   729  C  CA  . ASN   A 1 103 ? 44.71224 -3.66836  19.07632  1.000 92.34560  ? 103 ASN   A CA  1 
ATOM   730  C  C   . ASN   A 1 103 ? 43.29007 -3.15909  18.87147  1.000 90.37231  ? 103 ASN   A C   1 
ATOM   731  O  O   . ASN   A 1 103 ? 42.32421 -3.83937  19.23323  1.000 90.38146  ? 103 ASN   A O   1 
ATOM   732  C  CB  . ASN   A 1 103 ? 44.92861 -4.99527  18.35051  1.000 91.62090  ? 103 ASN   A CB  1 
ATOM   733  C  CG  . ASN   A 1 103 ? 44.95039 -4.84624  16.83729  1.000 89.06899  ? 103 ASN   A CG  1 
ATOM   734  O  OD1 . ASN   A 1 103 ? 44.43523 -3.87499  16.28355  1.000 89.15398  ? 103 ASN   A OD1 1 
ATOM   735  N  ND2 . ASN   A 1 103 ? 45.54718 -5.82063  16.16036  1.000 85.54738  ? 103 ASN   A ND2 1 
ATOM   736  N  N   . ALA   A 1 104 ? 43.15990 -1.96123  18.29716  1.000 88.30306  ? 104 ALA   A N   1 
ATOM   737  C  CA  . ALA   A 1 104 ? 41.83752 -1.36717  18.13071  1.000 86.91394  ? 104 ALA   A CA  1 
ATOM   738  C  C   . ALA   A 1 104 ? 41.03890 -2.05080  17.02829  1.000 93.49346  ? 104 ALA   A C   1 
ATOM   739  O  O   . ALA   A 1 104 ? 39.80341 -2.02577  17.05593  1.000 93.46931  ? 104 ALA   A O   1 
ATOM   740  C  CB  . ALA   A 1 104 ? 41.96503 0.12840   17.84256  1.000 83.98608  ? 104 ALA   A CB  1 
ATOM   741  N  N   . HIS   A 1 105 ? 41.71582 -2.66416  16.05579  1.000 94.57252  ? 105 HIS   A N   1 
ATOM   742  C  CA  . HIS   A 1 105 ? 41.00137 -3.28155  14.94264  1.000 93.20665  ? 105 HIS   A CA  1 
ATOM   743  C  C   . HIS   A 1 105 ? 40.34930 -4.59544  15.35618  1.000 91.23933  ? 105 HIS   A C   1 
ATOM   744  O  O   . HIS   A 1 105 ? 39.20408 -4.87136  14.97886  1.000 92.29305  ? 105 HIS   A O   1 
ATOM   745  C  CB  . HIS   A 1 105 ? 41.95047 -3.49885  13.76262  1.000 99.92651  ? 105 HIS   A CB  1 
ATOM   746  C  CG  . HIS   A 1 105 ? 42.26385 -2.24871  13.00148  1.000 107.28107 ? 105 HIS   A CG  1 
ATOM   747  N  ND1 . HIS   A 1 105 ? 41.56748 -1.07324  13.18323  1.000 102.81115 ? 105 HIS   A ND1 1 
ATOM   748  C  CD2 . HIS   A 1 105 ? 43.19612 -1.99133  12.05378  1.000 107.87602 ? 105 HIS   A CD2 1 
ATOM   749  C  CE1 . HIS   A 1 105 ? 42.05765 -0.14566  12.38056  1.000 103.25617 ? 105 HIS   A CE1 1 
ATOM   750  N  NE2 . HIS   A 1 105 ? 43.04715 -0.67661  11.68506  1.000 106.27724 ? 105 HIS   A NE2 1 
ATOM   751  N  N   . LYS   A 1 106 ? 41.05791 -5.41747  16.12812  1.000 90.42523  ? 106 LYS   A N   1 
ATOM   752  C  CA  . LYS   A 1 106 ? 40.57341 -6.73663  16.50884  1.000 95.19878  ? 106 LYS   A CA  1 
ATOM   753  C  C   . LYS   A 1 106 ? 40.21700 -6.84378  17.98537  1.000 92.18978  ? 106 LYS   A C   1 
ATOM   754  O  O   . LYS   A 1 106 ? 39.79255 -7.91651  18.42860  1.000 98.18981  ? 106 LYS   A O   1 
ATOM   755  C  CB  . LYS   A 1 106 ? 41.61089 -7.80098  16.13135  1.000 101.51958 ? 106 LYS   A CB  1 
ATOM   756  C  CG  . LYS   A 1 106 ? 41.73621 -7.99003  14.62495  1.000 99.69925  ? 106 LYS   A CG  1 
ATOM   757  C  CD  . LYS   A 1 106 ? 43.03526 -8.66841  14.22824  1.000 95.17853  ? 106 LYS   A CD  1 
ATOM   758  C  CE  . LYS   A 1 106 ? 43.16036 -8.74401  12.71327  1.000 90.72067  ? 106 LYS   A CE  1 
ATOM   759  N  NZ  . LYS   A 1 106 ? 44.49259 -9.24673  12.28033  1.000 99.55020  ? 106 LYS   A NZ  1 
ATOM   760  N  N   . GLY   A 1 107 ? 40.37450 -5.76711  18.75299  1.000 94.25947  ? 107 GLY   A N   1 
ATOM   761  C  CA  . GLY   A 1 107 ? 39.87249 -5.69837  20.11272  1.000 96.49264  ? 107 GLY   A CA  1 
ATOM   762  C  C   . GLY   A 1 107 ? 40.39816 -6.74359  21.07517  1.000 97.68541  ? 107 GLY   A C   1 
ATOM   763  O  O   . GLY   A 1 107 ? 39.61594 -7.49921  21.65994  1.000 92.33177  ? 107 GLY   A O   1 
ATOM   764  N  N   . PHE   A 1 108 ? 41.71580 -6.79671  21.25721  1.000 100.92152 ? 108 PHE   A N   1 
ATOM   765  C  CA  . PHE   A 1 108 ? 42.31817 -7.68252  22.24177  1.000 98.78753  ? 108 PHE   A CA  1 
ATOM   766  C  C   . PHE   A 1 108 ? 43.50532 -6.98082  22.88315  1.000 87.13553  ? 108 PHE   A C   1 
ATOM   767  O  O   . PHE   A 1 108 ? 44.19287 -6.17972  22.24464  1.000 86.79191  ? 108 PHE   A O   1 
ATOM   768  C  CB  . PHE   A 1 108 ? 42.75500 -9.02132  21.62312  1.000 102.54844 ? 108 PHE   A CB  1 
ATOM   769  C  CG  . PHE   A 1 108 ? 43.92325 -8.91105  20.68304  1.000 99.13674  ? 108 PHE   A CG  1 
ATOM   770  C  CD1 . PHE   A 1 108 ? 43.72953 -8.59080  19.34961  1.000 97.65484  ? 108 PHE   A CD1 1 
ATOM   771  C  CD2 . PHE   A 1 108 ? 45.21454 -9.14592  21.12987  1.000 97.45030  ? 108 PHE   A CD2 1 
ATOM   772  C  CE1 . PHE   A 1 108 ? 44.80196 -8.49582  18.48203  1.000 100.32230 ? 108 PHE   A CE1 1 
ATOM   773  C  CE2 . PHE   A 1 108 ? 46.29052 -9.05054  20.26808  1.000 102.11706 ? 108 PHE   A CE2 1 
ATOM   774  C  CZ  . PHE   A 1 108 ? 46.08393 -8.72529  18.94233  1.000 107.82621 ? 108 PHE   A CZ  1 
ATOM   775  N  N   . CYS   A 1 109 ? 43.73757 -7.29153  24.15555  1.000 79.90192  ? 109 CYS   A N   1 
ATOM   776  C  CA  . CYS   A 1 109 ? 44.80767 -6.64484  24.90180  1.000 80.16914  ? 109 CYS   A CA  1 
ATOM   777  C  C   . CYS   A 1 109 ? 46.16454 -7.17349  24.45443  1.000 80.98209  ? 109 CYS   A C   1 
ATOM   778  O  O   . CYS   A 1 109 ? 46.38501 -8.38736  24.40075  1.000 88.58213  ? 109 CYS   A O   1 
ATOM   779  C  CB  . CYS   A 1 109 ? 44.61738 -6.87080  26.40072  1.000 78.97839  ? 109 CYS   A CB  1 
ATOM   780  S  SG  . CYS   A 1 109 ? 45.81770 -6.01314  27.44489  1.000 66.38732  ? 109 CYS   A SG  1 
ATOM   781  N  N   . MET   A 1 110 ? 47.07398 -6.25601  24.13014  1.000 83.15835  ? 110 MET   A N   1 
ATOM   782  C  CA  . MET   A 1 110 ? 48.43425 -6.60021  23.73559  1.000 85.33711  ? 110 MET   A CA  1 
ATOM   783  C  C   . MET   A 1 110 ? 49.42146 -6.52341  24.89045  1.000 85.51066  ? 110 MET   A C   1 
ATOM   784  O  O   . MET   A 1 110 ? 50.25409 -7.42138  25.04846  1.000 88.36498  ? 110 MET   A O   1 
ATOM   785  C  CB  . MET   A 1 110 ? 48.90996 -5.67946  22.60670  1.000 85.47784  ? 110 MET   A CB  1 
ATOM   786  C  CG  . MET   A 1 110 ? 48.08066 -5.75811  21.33732  1.000 91.75186  ? 110 MET   A CG  1 
ATOM   787  S  SD  . MET   A 1 110 ? 48.64313 -4.58765  20.08616  1.000 93.99873  ? 110 MET   A SD  1 
ATOM   788  C  CE  . MET   A 1 110 ? 50.35705 -5.07802  19.90980  1.000 100.24813 ? 110 MET   A CE  1 
ATOM   789  N  N   . SER   A 1 111 ? 49.34728 -5.47162  25.70264  1.000 86.66927  ? 111 SER   A N   1 
ATOM   790  C  CA  . SER   A 1 111 ? 50.29223 -5.28357  26.79540  1.000 86.94307  ? 111 SER   A CA  1 
ATOM   791  C  C   . SER   A 1 111 ? 49.58697 -4.64705  27.98407  1.000 89.32971  ? 111 SER   A C   1 
ATOM   792  O  O   . SER   A 1 111 ? 48.51276 -4.05871  27.85154  1.000 91.96280  ? 111 SER   A O   1 
ATOM   793  C  CB  . SER   A 1 111 ? 51.48629 -4.41921  26.36653  1.000 90.57891  ? 111 SER   A CB  1 
ATOM   794  O  OG  . SER   A 1 111 ? 52.18884 -5.01529  25.28990  1.000 102.27760 ? 111 SER   A OG  1 
ATOM   795  N  N   . THR   A 1 112 ? 50.21931 -4.75626  29.15354  1.000 91.82676  ? 112 THR   A N   1 
ATOM   796  C  CA  . THR   A 1 112 ? 49.67774 -4.19627  30.39376  1.000 89.98707  ? 112 THR   A CA  1 
ATOM   797  C  C   . THR   A 1 112 ? 50.83104 -3.59667  31.19435  1.000 92.91752  ? 112 THR   A C   1 
ATOM   798  O  O   . THR   A 1 112 ? 51.53794 -4.31596  31.90760  1.000 95.31488  ? 112 THR   A O   1 
ATOM   799  C  CB  . THR   A 1 112 ? 48.93788 -5.25544  31.20395  1.000 89.58470  ? 112 THR   A CB  1 
ATOM   800  O  OG1 . THR   A 1 112 ? 47.86522 -5.79687  30.42227  1.000 94.52101  ? 112 THR   A OG1 1 
ATOM   801  C  CG2 . THR   A 1 112 ? 48.37150 -4.64892  32.48115  1.000 84.34786  ? 112 THR   A CG2 1 
ATOM   802  N  N   . LEU   A 1 113 ? 51.02027 -2.28353  31.06905  1.000 89.39537  ? 113 LEU   A N   1 
ATOM   803  C  CA  . LEU   A 1 113 ? 52.01669 -1.57475  31.85980  1.000 86.04642  ? 113 LEU   A CA  1 
ATOM   804  C  C   . LEU   A 1 113 ? 51.51115 -1.41578  33.28848  1.000 86.61935  ? 113 LEU   A C   1 
ATOM   805  O  O   . LEU   A 1 113 ? 50.50090 -0.74353  33.52596  1.000 87.58450  ? 113 LEU   A O   1 
ATOM   806  C  CB  . LEU   A 1 113 ? 52.30364 -0.20889  31.24048  1.000 77.96224  ? 113 LEU   A CB  1 
ATOM   807  C  CG  . LEU   A 1 113 ? 52.33045 -0.12914  29.71124  1.000 73.85760  ? 113 LEU   A CG  1 
ATOM   808  C  CD1 . LEU   A 1 113 ? 52.45696 1.31550   29.25236  1.000 77.20453  ? 113 LEU   A CD1 1 
ATOM   809  C  CD2 . LEU   A 1 113 ? 53.45772 -0.97515  29.14207  1.000 82.43972  ? 113 LEU   A CD2 1 
ATOM   810  N  N   . ARG   A 1 114 ? 52.20668 -2.03586  34.23526  1.000 86.58164  ? 114 ARG   A N   1 
ATOM   811  C  CA  . ARG   A 1 114 ? 51.83655 -1.96630  35.64849  1.000 88.53566  ? 114 ARG   A CA  1 
ATOM   812  C  C   . ARG   A 1 114 ? 52.77346 -1.01473  36.39106  1.000 92.56963  ? 114 ARG   A C   1 
ATOM   813  O  O   . ARG   A 1 114 ? 53.45868 -1.37926  37.34720  1.000 100.36386 ? 114 ARG   A O   1 
ATOM   814  C  CB  . ARG   A 1 114 ? 51.85343 -3.36287  36.26397  1.000 94.39725  ? 114 ARG   A CB  1 
ATOM   815  C  CG  . ARG   A 1 114 ? 51.73246 -4.48375  35.23963  1.000 98.50545  ? 114 ARG   A CG  1 
ATOM   816  C  CD  . ARG   A 1 114 ? 51.63770 -5.84961  35.90060  1.000 102.72826 ? 114 ARG   A CD  1 
ATOM   817  N  NE  . ARG   A 1 114 ? 50.28843 -6.13823  36.37183  1.000 108.52300 ? 114 ARG   A NE  1 
ATOM   818  C  CZ  . ARG   A 1 114 ? 49.36842 -6.77638  35.66100  1.000 98.81499  ? 114 ARG   A CZ  1 
ATOM   819  N  NH1 . ARG   A 1 114 ? 49.61947 -7.21168  34.43690  1.000 94.99356  ? 114 ARG   A NH1 1 
ATOM   820  N  NH2 . ARG   A 1 114 ? 48.16668 -6.98402  36.19186  1.000 91.37088  ? 114 ARG   A NH2 1 
ATOM   821  N  N   . THR   A 1 115 ? 52.78860 0.23387   35.92574  1.000 79.74237  ? 115 THR   A N   1 
ATOM   822  C  CA  . THR   A 1 115 ? 53.72485 1.24538   36.40197  1.000 78.97705  ? 115 THR   A CA  1 
ATOM   823  C  C   . THR   A 1 115 ? 53.14968 2.14162   37.49110  1.000 88.89488  ? 115 THR   A C   1 
ATOM   824  O  O   . THR   A 1 115 ? 53.86418 2.48918   38.43639  1.000 95.47402  ? 115 THR   A O   1 
ATOM   825  C  CB  . THR   A 1 115 ? 54.19513 2.11695   35.23302  1.000 76.03687  ? 115 THR   A CB  1 
ATOM   826  O  OG1 . THR   A 1 115 ? 53.06915 2.78970   34.65699  1.000 83.98982  ? 115 THR   A OG1 1 
ATOM   827  C  CG2 . THR   A 1 115 ? 54.86459 1.26306   34.16674  1.000 76.89887  ? 115 THR   A CG2 1 
ATOM   828  N  N   . HIS   A 1 116 ? 51.88089 2.52880   37.38395  1.000 87.97988  ? 116 HIS   A N   1 
ATOM   829  C  CA  . HIS   A 1 116 ? 51.29874 3.45461   38.34700  1.000 84.04721  ? 116 HIS   A CA  1 
ATOM   830  C  C   . HIS   A 1 116 ? 51.15929 2.80590   39.71932  1.000 83.72627  ? 116 HIS   A C   1 
ATOM   831  O  O   . HIS   A 1 116 ? 50.82844 1.62249   39.83663  1.000 84.17303  ? 116 HIS   A O   1 
ATOM   832  C  CB  . HIS   A 1 116 ? 49.93310 3.94010   37.86193  1.000 76.91894  ? 116 HIS   A CB  1 
ATOM   833  C  CG  . HIS   A 1 116 ? 50.00542 4.98704   36.79444  1.000 75.00931  ? 116 HIS   A CG  1 
ATOM   834  N  ND1 . HIS   A 1 116 ? 49.96214 6.33617   37.07281  1.000 77.45592  ? 116 HIS   A ND1 1 
ATOM   835  C  CD2 . HIS   A 1 116 ? 50.11230 4.88410   35.44853  1.000 75.69355  ? 116 HIS   A CD2 1 
ATOM   836  C  CE1 . HIS   A 1 116 ? 50.04195 7.01939   35.94501  1.000 79.87687  ? 116 HIS   A CE1 1 
ATOM   837  N  NE2 . HIS   A 1 116 ? 50.13385 6.16200   34.94449  1.000 78.28254  ? 116 HIS   A NE2 1 
ATOM   838  N  N   . LYS   A 1 117 ? 51.41638 3.59702   40.76519  1.000 80.04968  ? 117 LYS   A N   1 
ATOM   839  C  CA  . LYS   A 1 117 ? 51.23243 3.12218   42.13224  1.000 80.26533  ? 117 LYS   A CA  1 
ATOM   840  C  C   . LYS   A 1 117 ? 49.76525 3.13412   42.54495  1.000 85.78207  ? 117 LYS   A C   1 
ATOM   841  O  O   . LYS   A 1 117 ? 49.33205 2.26094   43.30836  1.000 81.36252  ? 117 LYS   A O   1 
ATOM   842  C  CB  . LYS   A 1 117 ? 52.04447 3.97728   43.10787  1.000 87.58437  ? 117 LYS   A CB  1 
ATOM   843  C  CG  . LYS   A 1 117 ? 53.54283 3.71710   43.10003  1.000 93.34861  ? 117 LYS   A CG  1 
ATOM   844  C  CD  . LYS   A 1 117 ? 54.21985 4.48034   44.23244  1.000 99.59995  ? 117 LYS   A CD  1 
ATOM   845  C  CE  . LYS   A 1 117 ? 55.68916 4.11399   44.36349  1.000 95.59798  ? 117 LYS   A CE  1 
ATOM   846  N  NZ  . LYS   A 1 117 ? 56.47101 4.51629   43.16443  1.000 96.80111  ? 117 LYS   A NZ  1 
ATOM   847  N  N   . ASP   A 1 118 ? 48.99125 4.10593   42.05283  1.000 95.11387  ? 118 ASP   A N   1 
ATOM   848  C  CA  . ASP   A 1 118 ? 47.58114 4.22039   42.40710  1.000 91.26984  ? 118 ASP   A CA  1 
ATOM   849  C  C   . ASP   A 1 118 ? 46.70419 4.15122   41.15905  1.000 82.95921  ? 118 ASP   A C   1 
ATOM   850  O  O   . ASP   A 1 118 ? 47.12381 3.61316   40.12661  1.000 84.57645  ? 118 ASP   A O   1 
ATOM   851  C  CB  . ASP   A 1 118 ? 47.32897 5.51890   43.17551  1.000 89.46291  ? 118 ASP   A CB  1 
ATOM   852  C  CG  . ASP   A 1 118 ? 46.15663 5.41116   44.13616  1.000 89.52711  ? 118 ASP   A CG  1 
ATOM   853  O  OD1 . ASP   A 1 118 ? 45.26714 4.57572   43.89623  1.000 81.87510  ? 118 ASP   A OD1 1 
ATOM   854  O  OD2 . ASP   A 1 118 ? 46.12449 6.17125   45.12906  1.000 92.27766  ? 118 ASP   A OD2 1 
ATOM   855  N  N   . TYR   A 1 119 ? 45.49118 4.70036   41.24197  1.000 75.85261  ? 119 TYR   A N   1 
ATOM   856  C  CA  . TYR   A 1 119 ? 44.58742 4.70254   40.09850  1.000 72.25673  ? 119 TYR   A CA  1 
ATOM   857  C  C   . TYR   A 1 119 ? 45.20508 5.48116   38.94550  1.000 69.75716  ? 119 TYR   A C   1 
ATOM   858  O  O   . TYR   A 1 119 ? 45.89826 6.48032   39.15146  1.000 77.39886  ? 119 TYR   A O   1 
ATOM   859  C  CB  . TYR   A 1 119 ? 43.23592 5.32634   40.46601  1.000 78.03425  ? 119 TYR   A CB  1 
ATOM   860  C  CG  . TYR   A 1 119 ? 42.38098 4.54357   41.44479  1.000 81.49351  ? 119 TYR   A CG  1 
ATOM   861  C  CD1 . TYR   A 1 119 ? 42.87296 3.42597   42.10745  1.000 84.45101  ? 119 TYR   A CD1 1 
ATOM   862  C  CD2 . TYR   A 1 119 ? 41.06684 4.92414   41.69443  1.000 79.03096  ? 119 TYR   A CD2 1 
ATOM   863  C  CE1 . TYR   A 1 119 ? 42.08168 2.71742   42.99902  1.000 89.63074  ? 119 TYR   A CE1 1 
ATOM   864  C  CE2 . TYR   A 1 119 ? 40.27188 4.22279   42.57788  1.000 68.90520  ? 119 TYR   A CE2 1 
ATOM   865  C  CZ  . TYR   A 1 119 ? 40.78366 3.11991   43.22806  1.000 78.40697  ? 119 TYR   A CZ  1 
ATOM   866  O  OH  . TYR   A 1 119 ? 39.99641 2.41644   44.11022  1.000 78.28374  ? 119 TYR   A OH  1 
ATOM   867  N  N   . VAL   A 1 120 ? 44.96386 5.00959   37.72704  1.000 65.29955  ? 120 VAL   A N   1 
ATOM   868  C  CA  . VAL   A 1 120 ? 45.35683 5.72013   36.51613  1.000 68.36803  ? 120 VAL   A CA  1 
ATOM   869  C  C   . VAL   A 1 120 ? 44.13180 6.46728   36.01228  1.000 69.70093  ? 120 VAL   A C   1 
ATOM   870  O  O   . VAL   A 1 120 ? 43.12656 5.84797   35.64309  1.000 70.82987  ? 120 VAL   A O   1 
ATOM   871  C  CB  . VAL   A 1 120 ? 45.90411 4.76250   35.44773  1.000 66.54106  ? 120 VAL   A CB  1 
ATOM   872  C  CG1 . VAL   A 1 120 ? 46.72931 5.53070   34.43738  1.000 63.85732  ? 120 VAL   A CG1 1 
ATOM   873  C  CG2 . VAL   A 1 120 ? 46.72439 3.65484   36.09734  1.000 74.99406  ? 120 VAL   A CG2 1 
ATOM   874  N  N   . LYS   A 1 121 ? 44.21080 7.79630   35.99473  1.000 65.66946  ? 121 LYS   A N   1 
ATOM   875  C  CA  . LYS   A 1 121 ? 43.02948 8.62850   35.80947  1.000 60.70936  ? 121 LYS   A CA  1 
ATOM   876  C  C   . LYS   A 1 121 ? 42.89305 9.20515   34.40633  1.000 59.22645  ? 121 LYS   A C   1 
ATOM   877  O  O   . LYS   A 1 121 ? 41.78005 9.24668   33.87373  1.000 63.63413  ? 121 LYS   A O   1 
ATOM   878  C  CB  . LYS   A 1 121 ? 43.03225 9.77375   36.82620  1.000 68.28595  ? 121 LYS   A CB  1 
ATOM   879  C  CG  . LYS   A 1 121 ? 41.64801 10.30695  37.14766  1.000 73.02273  ? 121 LYS   A CG  1 
ATOM   880  C  CD  . LYS   A 1 121 ? 40.83761 9.27818   37.92046  1.000 65.17688  ? 121 LYS   A CD  1 
ATOM   881  C  CE  . LYS   A 1 121 ? 39.38445 9.69981   38.05419  1.000 65.62633  ? 121 LYS   A CE  1 
ATOM   882  N  NZ  . LYS   A 1 121 ? 38.66958 9.65463   36.74907  1.000 67.26177  ? 121 LYS   A NZ  1 
ATOM   883  N  N   . ALA   A 1 122 ? 43.98202 9.65925   33.78727  1.000 57.15392  ? 122 ALA   A N   1 
ATOM   884  C  CA  . ALA   A 1 122 ? 43.87610 10.39040  32.53330  1.000 65.98558  ? 122 ALA   A CA  1 
ATOM   885  C  C   . ALA   A 1 122 ? 45.00701 10.01140  31.58738  1.000 68.02484  ? 122 ALA   A C   1 
ATOM   886  O  O   . ALA   A 1 122 ? 46.07099 9.53910   32.00082  1.000 67.54481  ? 122 ALA   A O   1 
ATOM   887  C  CB  . ALA   A 1 122 ? 43.88061 11.90676  32.76747  1.000 80.12071  ? 122 ALA   A CB  1 
ATOM   888  N  N   . LEU   A 1 123 ? 44.75382 10.24224  30.29864  1.000 69.40155  ? 123 LEU   A N   1 
ATOM   889  C  CA  . LEU   A 1 123 ? 45.71135 10.00301  29.22977  1.000 73.41394  ? 123 LEU   A CA  1 
ATOM   890  C  C   . LEU   A 1 123 ? 45.74968 11.20997  28.30310  1.000 76.90894  ? 123 LEU   A C   1 
ATOM   891  O  O   . LEU   A 1 123 ? 44.70584 11.76112  27.94071  1.000 70.56523  ? 123 LEU   A O   1 
ATOM   892  C  CB  . LEU   A 1 123 ? 45.35241 8.74785   28.42271  1.000 67.54845  ? 123 LEU   A CB  1 
ATOM   893  C  CG  . LEU   A 1 123 ? 45.23313 7.42443   29.17815  1.000 69.12903  ? 123 LEU   A CG  1 
ATOM   894  C  CD1 . LEU   A 1 123 ? 44.80725 6.31163   28.23549  1.000 72.18864  ? 123 LEU   A CD1 1 
ATOM   895  C  CD2 . LEU   A 1 123 ? 46.54370 7.07651   29.85514  1.000 73.10645  ? 123 LEU   A CD2 1 
ATOM   896  N  N   . ALA   A 1 124 ? 46.95811 11.61410  27.92622  1.000 77.41426  ? 124 ALA   A N   1 
ATOM   897  C  CA  . ALA   A 1 124 ? 47.18088 12.67783  26.95771  1.000 70.00916  ? 124 ALA   A CA  1 
ATOM   898  C  C   . ALA   A 1 124 ? 47.78822 12.08760  25.69318  1.000 74.51324  ? 124 ALA   A C   1 
ATOM   899  O  O   . ALA   A 1 124 ? 48.58655 11.14782  25.76067  1.000 82.50668  ? 124 ALA   A O   1 
ATOM   900  C  CB  . ALA   A 1 124 ? 48.10079 13.76107  27.52421  1.000 73.30011  ? 124 ALA   A CB  1 
ATOM   901  N  N   . TYR   A 1 125 ? 47.41710 12.64684  24.54215  1.000 76.42125  ? 125 TYR   A N   1 
ATOM   902  C  CA  . TYR   A 1 125 ? 47.81068 12.08814  23.25691  1.000 84.02609  ? 125 TYR   A CA  1 
ATOM   903  C  C   . TYR   A 1 125 ? 48.25809 13.18768  22.30545  1.000 85.41313  ? 125 TYR   A C   1 
ATOM   904  O  O   . TYR   A 1 125 ? 47.70893 14.29289  22.31252  1.000 86.18050  ? 125 TYR   A O   1 
ATOM   905  C  CB  . TYR   A 1 125 ? 46.65924 11.29426  22.62723  1.000 85.44114  ? 125 TYR   A CB  1 
ATOM   906  C  CG  . TYR   A 1 125 ? 46.98098 10.71187  21.26961  1.000 89.72900  ? 125 TYR   A CG  1 
ATOM   907  C  CD1 . TYR   A 1 125 ? 48.09282 9.90063   21.08728  1.000 94.11073  ? 125 TYR   A CD1 1 
ATOM   908  C  CD2 . TYR   A 1 125 ? 46.16477 10.96027  20.17410  1.000 89.67844  ? 125 TYR   A CD2 1 
ATOM   909  C  CE1 . TYR   A 1 125 ? 48.39107 9.36329   19.85021  1.000 97.16539  ? 125 TYR   A CE1 1 
ATOM   910  C  CE2 . TYR   A 1 125 ? 46.45263 10.42384  18.93337  1.000 93.77089  ? 125 TYR   A CE2 1 
ATOM   911  C  CZ  . TYR   A 1 125 ? 47.56716 9.62635   18.77700  1.000 97.55413  ? 125 TYR   A CZ  1 
ATOM   912  O  OH  . TYR   A 1 125 ? 47.86085 9.09036   17.54383  1.000 97.39659  ? 125 TYR   A OH  1 
ATOM   913  N  N   . ALA   A 1 126 ? 49.26258 12.86963  21.48983  1.000 84.59036  ? 126 ALA   A N   1 
ATOM   914  C  CA  . ALA   A 1 126 ? 49.72324 13.72745  20.40295  1.000 87.59602  ? 126 ALA   A CA  1 
ATOM   915  C  C   . ALA   A 1 126 ? 49.83598 12.85845  19.15809  1.000 92.88324  ? 126 ALA   A C   1 
ATOM   916  O  O   . ALA   A 1 126 ? 50.65369 11.93064  19.11793  1.000 98.48579  ? 126 ALA   A O   1 
ATOM   917  C  CB  . ALA   A 1 126 ? 51.06029 14.38690  20.73966  1.000 88.36004  ? 126 ALA   A CB  1 
ATOM   918  N  N   . LYS   A 1 127 ? 49.01093 13.15304  18.14845  1.000 93.13268  ? 127 LYS   A N   1 
ATOM   919  C  CA  . LYS   A 1 127 ? 48.92844 12.30010  16.96888  1.000 100.23139 ? 127 LYS   A CA  1 
ATOM   920  C  C   . LYS   A 1 127 ? 50.00667 12.60354  15.93763  1.000 108.63009 ? 127 LYS   A C   1 
ATOM   921  O  O   . LYS   A 1 127 ? 50.32668 11.72851  15.12576  1.000 115.40325 ? 127 LYS   A O   1 
ATOM   922  C  CB  . LYS   A 1 127 ? 47.54514 12.41938  16.31920  1.000 101.68713 ? 127 LYS   A CB  1 
ATOM   923  C  CG  . LYS   A 1 127 ? 47.43836 13.45934  15.21432  1.000 104.27884 ? 127 LYS   A CG  1 
ATOM   924  C  CD  . LYS   A 1 127 ? 46.13379 13.30210  14.44674  1.000 104.32103 ? 127 LYS   A CD  1 
ATOM   925  C  CE  . LYS   A 1 127 ? 46.10856 14.17506  13.20228  1.000 99.61944  ? 127 LYS   A CE  1 
ATOM   926  N  NZ  . LYS   A 1 127 ? 44.87965 13.94676  12.39131  1.000 99.19133  ? 127 LYS   A NZ  1 
ATOM   927  N  N   . ASP   A 1 128 ? 50.57009 13.81401  15.94256  1.000 108.11286 ? 128 ASP   A N   1 
ATOM   928  C  CA  . ASP   A 1 128 ? 51.66826 14.10725  15.02750  1.000 115.20354 ? 128 ASP   A CA  1 
ATOM   929  C  C   . ASP   A 1 128 ? 52.93715 13.37716  15.44733  1.000 110.45029 ? 128 ASP   A C   1 
ATOM   930  O  O   . ASP   A 1 128 ? 53.71986 12.93770  14.59666  1.000 113.97251 ? 128 ASP   A O   1 
ATOM   931  C  CB  . ASP   A 1 128 ? 51.91139 15.61489  14.95547  1.000 113.22432 ? 128 ASP   A CB  1 
ATOM   932  C  CG  . ASP   A 1 128 ? 50.75907 16.36188  14.31162  1.000 106.11023 ? 128 ASP   A CG  1 
ATOM   933  O  OD1 . ASP   A 1 128 ? 49.68405 15.75440  14.12371  1.000 105.82153 ? 128 ASP   A OD1 1 
ATOM   934  O  OD2 . ASP   A 1 128 ? 50.93083 17.55565  13.98685  1.000 97.37142  ? 128 ASP   A OD2 1 
ATOM   935  N  N   . LYS   A 1 129 ? 53.15292 13.23450  16.75316  1.000 99.40326  ? 129 LYS   A N   1 
ATOM   936  C  CA  . LYS   A 1 129 ? 54.29434 12.50359  17.28263  1.000 98.49078  ? 129 LYS   A CA  1 
ATOM   937  C  C   . LYS   A 1 129 ? 53.98213 11.04455  17.58273  1.000 107.00514 ? 129 LYS   A C   1 
ATOM   938  O  O   . LYS   A 1 129 ? 54.91577 10.26625  17.80871  1.000 113.69500 ? 129 LYS   A O   1 
ATOM   939  C  CB  . LYS   A 1 129 ? 54.80486 13.17592  18.56257  1.000 97.42399  ? 129 LYS   A CB  1 
ATOM   940  C  CG  . LYS   A 1 129 ? 55.48652 14.51576  18.34842  1.000 99.40002  ? 129 LYS   A CG  1 
ATOM   941  C  CD  . LYS   A 1 129 ? 56.89159 14.33938  17.79814  1.000 107.35729 ? 129 LYS   A CD  1 
ATOM   942  C  CE  . LYS   A 1 129 ? 57.63638 15.66384  17.75842  1.000 101.48463 ? 129 LYS   A CE  1 
ATOM   943  N  NZ  . LYS   A 1 129 ? 59.04724 15.49612  17.31319  1.000 103.75443 ? 129 LYS   A NZ  1 
ATOM   944  N  N   . GLU   A 1 130 ? 52.70640 10.65868  17.58079  1.000 108.63953 ? 130 GLU   A N   1 
ATOM   945  C  CA  . GLU   A 1 130 ? 52.27042 9.34300   18.04547  1.000 101.87019 ? 130 GLU   A CA  1 
ATOM   946  C  C   . GLU   A 1 130 ? 52.81621 9.07485   19.44797  1.000 96.95349  ? 130 GLU   A C   1 
ATOM   947  O  O   . GLU   A 1 130 ? 53.49217 8.07899   19.71193  1.000 92.72666  ? 130 GLU   A O   1 
ATOM   948  C  CB  . GLU   A 1 130 ? 52.68356 8.24247   17.06309  1.000 92.58104  ? 130 GLU   A CB  1 
ATOM   949  C  CG  . GLU   A 1 130 ? 51.96578 8.29869   15.72271  1.000 88.96677  ? 130 GLU   A CG  1 
ATOM   950  C  CD  . GLU   A 1 130 ? 50.50157 7.91458   15.82563  1.000 94.63259  ? 130 GLU   A CD  1 
ATOM   951  O  OE1 . GLU   A 1 130 ? 50.12448 7.25609   16.81818  1.000 92.36190  ? 130 GLU   A OE1 1 
ATOM   952  O  OE2 . GLU   A 1 130 ? 49.72678 8.27124   14.91317  1.000 102.74557 ? 130 GLU   A OE2 1 
ATOM   953  N  N   . LEU   A 1 131 ? 52.51180 10.00566  20.35060  1.000 94.11286  ? 131 LEU   A N   1 
ATOM   954  C  CA  . LEU   A 1 131 ? 53.07138 10.01882  21.69527  1.000 89.41003  ? 131 LEU   A CA  1 
ATOM   955  C  C   . LEU   A 1 131 ? 51.94338 10.05254  22.71507  1.000 88.49706  ? 131 LEU   A C   1 
ATOM   956  O  O   . LEU   A 1 131 ? 50.96851 10.78981  22.54403  1.000 90.40901  ? 131 LEU   A O   1 
ATOM   957  C  CB  . LEU   A 1 131 ? 53.99804 11.23060  21.87796  1.000 89.10264  ? 131 LEU   A CB  1 
ATOM   958  C  CG  . LEU   A 1 131 ? 54.55618 11.57420  23.25970  1.000 93.08270  ? 131 LEU   A CG  1 
ATOM   959  C  CD1 . LEU   A 1 131 ? 55.50232 10.49700  23.75415  1.000 90.28222  ? 131 LEU   A CD1 1 
ATOM   960  C  CD2 . LEU   A 1 131 ? 55.25914 12.92228  23.21319  1.000 105.08336 ? 131 LEU   A CD2 1 
ATOM   961  N  N   . VAL   A 1 132 ? 52.06693 9.25233   23.77743  1.000 88.71352  ? 132 VAL   A N   1 
ATOM   962  C  CA  . VAL   A 1 132 ? 51.02651 9.17714   24.79275  1.000 85.18528  ? 132 VAL   A CA  1 
ATOM   963  C  C   . VAL   A 1 132 ? 51.63452 9.43229   26.16491  1.000 79.23067  ? 132 VAL   A C   1 
ATOM   964  O  O   . VAL   A 1 132 ? 52.84442 9.32138   26.37099  1.000 79.92312  ? 132 VAL   A O   1 
ATOM   965  C  CB  . VAL   A 1 132 ? 50.28702 7.82138   24.77709  1.000 89.02576  ? 132 VAL   A CB  1 
ATOM   966  C  CG1 . VAL   A 1 132 ? 49.47621 7.67272   23.49932  1.000 88.31388  ? 132 VAL   A CG1 1 
ATOM   967  C  CG2 . VAL   A 1 132 ? 51.27328 6.67833   24.92012  1.000 94.39922  ? 132 VAL   A CG2 1 
ATOM   968  N  N   . ALA   A 1 133 ? 50.76629 9.78717   27.10787  1.000 76.69604  ? 133 ALA   A N   1 
ATOM   969  C  CA  . ALA   A 1 133 ? 51.17695 10.03261  28.48189  1.000 76.36394  ? 133 ALA   A CA  1 
ATOM   970  C  C   . ALA   A 1 133 ? 50.05482 9.60512   29.41454  1.000 75.22102  ? 133 ALA   A C   1 
ATOM   971  O  O   . ALA   A 1 133 ? 48.87976 9.83928   29.12735  1.000 79.03721  ? 133 ALA   A O   1 
ATOM   972  C  CB  . ALA   A 1 133 ? 51.52773 11.50696  28.71082  1.000 75.83244  ? 133 ALA   A CB  1 
ATOM   973  N  N   . SER   A 1 134 ? 50.42761 8.98420   30.52860  1.000 75.73310  ? 134 SER   A N   1 
ATOM   974  C  CA  . SER   A 1 134 ? 49.48197 8.48280   31.51537  1.000 74.85909  ? 134 SER   A CA  1 
ATOM   975  C  C   . SER   A 1 134 ? 49.69412 9.19387   32.84341  1.000 80.57621  ? 134 SER   A C   1 
ATOM   976  O  O   . SER   A 1 134 ? 50.83360 9.37534   33.28418  1.000 82.59324  ? 134 SER   A O   1 
ATOM   977  C  CB  . SER   A 1 134 ? 49.63397 6.97037   31.70838  1.000 78.37355  ? 134 SER   A CB  1 
ATOM   978  O  OG  . SER   A 1 134 ? 50.91445 6.64929   32.22359  1.000 82.50634  ? 134 SER   A OG  1 
ATOM   979  N  N   . ALA   A 1 135 ? 48.59356 9.58870   33.48333  1.000 78.75108  ? 135 ALA   A N   1 
ATOM   980  C  CA  . ALA   A 1 135 ? 48.65097 10.24737  34.77922  1.000 75.86438  ? 135 ALA   A CA  1 
ATOM   981  C  C   . ALA   A 1 135 ? 47.54699 9.70116   35.67140  1.000 70.66091  ? 135 ALA   A C   1 
ATOM   982  O  O   . ALA   A 1 135 ? 46.48749 9.28889   35.19234  1.000 65.55667  ? 135 ALA   A O   1 
ATOM   983  C  CB  . ALA   A 1 135 ? 48.51823 11.77046  34.64854  1.000 77.18383  ? 135 ALA   A CB  1 
ATOM   984  N  N   . GLY   A 1 136 ? 47.80240 9.70526   36.96980  1.000 70.69436  ? 136 GLY   A N   1 
ATOM   985  C  CA  . GLY   A 1 136 ? 46.84098 9.19720   37.91790  1.000 67.26982  ? 136 GLY   A CA  1 
ATOM   986  C  C   . GLY   A 1 136 ? 47.04413 9.76677   39.30164  1.000 67.51472  ? 136 GLY   A C   1 
ATOM   987  O  O   . GLY   A 1 136 ? 47.66729 10.81447  39.47886  1.000 72.18515  ? 136 GLY   A O   1 
ATOM   988  N  N   . LEU   A 1 137 ? 46.50787 9.05449   40.29176  1.000 67.93925  ? 137 LEU   A N   1 
ATOM   989  C  CA  . LEU   A 1 137 ? 46.56597 9.49006   41.68143  1.000 69.07896  ? 137 LEU   A CA  1 
ATOM   990  C  C   . LEU   A 1 137 ? 47.92870 9.26390   42.32265  1.000 70.49462  ? 137 LEU   A C   1 
ATOM   991  O  O   . LEU   A 1 137 ? 48.12186 9.65635   43.47847  1.000 67.85821  ? 137 LEU   A O   1 
ATOM   992  C  CB  . LEU   A 1 137 ? 45.49061 8.77233   42.50192  1.000 69.80958  ? 137 LEU   A CB  1 
ATOM   993  C  CG  . LEU   A 1 137 ? 44.07477 8.76400   41.92125  1.000 71.10442  ? 137 LEU   A CG  1 
ATOM   994  C  CD1 . LEU   A 1 137 ? 43.09765 8.13517   42.90405  1.000 73.46170  ? 137 LEU   A CD1 1 
ATOM   995  C  CD2 . LEU   A 1 137 ? 43.63086 10.16782  41.53599  1.000 69.91035  ? 137 LEU   A CD2 1 
ATOM   996  N  N   . ASP   A 1 138 ? 48.87026 8.64656   41.61237  1.000 72.75500  ? 138 ASP   A N   1 
ATOM   997  C  CA  . ASP   A 1 138 ? 50.20208 8.38809   42.14345  1.000 71.95255  ? 138 ASP   A CA  1 
ATOM   998  C  C   . ASP   A 1 138 ? 51.14023 9.58161   42.00563  1.000 73.51285  ? 138 ASP   A C   1 
ATOM   999  O  O   . ASP   A 1 138 ? 52.34276 9.43007   42.24837  1.000 79.88987  ? 138 ASP   A O   1 
ATOM   1000 C  CB  . ASP   A 1 138 ? 50.81355 7.16539   41.45402  1.000 76.08067  ? 138 ASP   A CB  1 
ATOM   1001 C  CG  . ASP   A 1 138 ? 50.92087 7.33694   39.95218  1.000 80.65716  ? 138 ASP   A CG  1 
ATOM   1002 O  OD1 . ASP   A 1 138 ? 50.12577 8.11431   39.38310  1.000 76.75942  ? 138 ASP   A OD1 1 
ATOM   1003 O  OD2 . ASP   A 1 138 ? 51.79846 6.69288   39.33988  1.000 86.24260  ? 138 ASP   A OD2 1 
ATOM   1004 N  N   . ARG   A 1 139 ? 50.62304 10.74843  41.61579  1.000 74.06435  ? 139 ARG   A N   1 
ATOM   1005 C  CA  . ARG   A 1 139 ? 51.39186 11.98895  41.51860  1.000 73.56447  ? 139 ARG   A CA  1 
ATOM   1006 C  C   . ARG   A 1 139 ? 52.52889 11.89648  40.50604  1.000 79.65855  ? 139 ARG   A C   1 
ATOM   1007 O  O   . ARG   A 1 139 ? 53.50608 12.64682  40.59692  1.000 82.83824  ? 139 ARG   A O   1 
ATOM   1008 C  CB  . ARG   A 1 139 ? 51.94345 12.40543  42.88742  1.000 70.16961  ? 139 ARG   A CB  1 
ATOM   1009 C  CG  . ARG   A 1 139 ? 50.89684 12.46686  43.98399  1.000 70.27865  ? 139 ARG   A CG  1 
ATOM   1010 C  CD  . ARG   A 1 139 ? 51.51982 12.21239  45.34517  1.000 66.98644  ? 139 ARG   A CD  1 
ATOM   1011 N  NE  . ARG   A 1 139 ? 50.53839 12.30422  46.41868  1.000 67.56659  ? 139 ARG   A NE  1 
ATOM   1012 C  CZ  . ARG   A 1 139 ? 50.32898 13.39144  47.14758  1.000 77.08457  ? 139 ARG   A CZ  1 
ATOM   1013 N  NH1 . ARG   A 1 139 ? 51.02612 14.49853  46.95241  1.000 78.03943  ? 139 ARG   A NH1 1 
ATOM   1014 N  NH2 . ARG   A 1 139 ? 49.39884 13.36651  48.09773  1.000 82.04450  ? 139 ARG   A NH2 1 
ATOM   1015 N  N   . GLN   A 1 140 ? 52.42439 10.99041  39.53633  1.000 81.37101  ? 140 GLN   A N   1 
ATOM   1016 C  CA  . GLN   A 1 140 ? 53.46810 10.80134  38.54023  1.000 84.65823  ? 140 GLN   A CA  1 
ATOM   1017 C  C   . GLN   A 1 140 ? 52.84430 10.67040  37.15978  1.000 81.40749  ? 140 GLN   A C   1 
ATOM   1018 O  O   . GLN   A 1 140 ? 51.79674 10.03761  36.99960  1.000 78.31138  ? 140 GLN   A O   1 
ATOM   1019 C  CB  . GLN   A 1 140 ? 54.32022 9.56261   38.84785  1.000 86.60127  ? 140 GLN   A CB  1 
ATOM   1020 C  CG  . GLN   A 1 140 ? 55.24406 9.71836   40.04485  1.000 90.91622  ? 140 GLN   A CG  1 
ATOM   1021 C  CD  . GLN   A 1 140 ? 56.12328 8.50236   40.26330  1.000 98.49633  ? 140 GLN   A CD  1 
ATOM   1022 O  OE1 . GLN   A 1 140 ? 55.75019 7.38131   39.91699  1.000 94.51134  ? 140 GLN   A OE1 1 
ATOM   1023 N  NE2 . GLN   A 1 140 ? 57.30235 8.71989   40.83466  1.000 118.25803 ? 140 GLN   A NE2 1 
ATOM   1024 N  N   . ILE   A 1 141 ? 53.49592 11.27217  36.16746  1.000 82.94504  ? 141 ILE   A N   1 
ATOM   1025 C  CA  . ILE   A 1 141 ? 53.07405 11.19862  34.77402  1.000 85.00362  ? 141 ILE   A CA  1 
ATOM   1026 C  C   . ILE   A 1 141 ? 54.15017 10.45701  33.99624  1.000 90.52631  ? 141 ILE   A C   1 
ATOM   1027 O  O   . ILE   A 1 141 ? 55.33977 10.76886  34.12211  1.000 96.24025  ? 141 ILE   A O   1 
ATOM   1028 C  CB  . ILE   A 1 141 ? 52.83017 12.59343  34.16869  1.000 89.64881  ? 141 ILE   A CB  1 
ATOM   1029 C  CG1 . ILE   A 1 141 ? 51.93085 13.43110  35.07897  1.000 92.98189  ? 141 ILE   A CG1 1 
ATOM   1030 C  CG2 . ILE   A 1 141 ? 52.21394 12.47036  32.78331  1.000 89.22377  ? 141 ILE   A CG2 1 
ATOM   1031 C  CD1 . ILE   A 1 141 ? 52.68744 14.39951  35.96097  1.000 96.14145  ? 141 ILE   A CD1 1 
ATOM   1032 N  N   . PHE   A 1 142 ? 53.73230 9.48387   33.19283  1.000 87.50952  ? 142 PHE   A N   1 
ATOM   1033 C  CA  . PHE   A 1 142 ? 54.64445 8.62579   32.44907  1.000 89.28488  ? 142 PHE   A CA  1 
ATOM   1034 C  C   . PHE   A 1 142 ? 54.44232 8.84021   30.95618  1.000 87.32962  ? 142 PHE   A C   1 
ATOM   1035 O  O   . PHE   A 1 142 ? 53.30446 8.85235   30.47751  1.000 90.13741  ? 142 PHE   A O   1 
ATOM   1036 C  CB  . PHE   A 1 142 ? 54.42025 7.15402   32.80405  1.000 87.29713  ? 142 PHE   A CB  1 
ATOM   1037 C  CG  . PHE   A 1 142 ? 54.48670 6.86180   34.27822  1.000 90.69497  ? 142 PHE   A CG  1 
ATOM   1038 C  CD1 . PHE   A 1 142 ? 55.36754 7.54499   35.10022  1.000 97.95218  ? 142 PHE   A CD1 1 
ATOM   1039 C  CD2 . PHE   A 1 142 ? 53.66392 5.90034   34.84138  1.000 91.19576  ? 142 PHE   A CD2 1 
ATOM   1040 C  CE1 . PHE   A 1 142 ? 55.42951 7.27258   36.45419  1.000 92.41728  ? 142 PHE   A CE1 1 
ATOM   1041 C  CE2 . PHE   A 1 142 ? 53.71962 5.62462   36.19572  1.000 90.61930  ? 142 PHE   A CE2 1 
ATOM   1042 C  CZ  . PHE   A 1 142 ? 54.60352 6.31235   37.00297  1.000 84.74574  ? 142 PHE   A CZ  1 
ATOM   1043 N  N   . LEU   A 1 143 ? 55.54265 8.99693   30.22536  1.000 82.78898  ? 143 LEU   A N   1 
ATOM   1044 C  CA  . LEU   A 1 143 ? 55.50741 9.20096   28.78361  1.000 88.41189  ? 143 LEU   A CA  1 
ATOM   1045 C  C   . LEU   A 1 143 ? 55.81191 7.89565   28.05896  1.000 92.96325  ? 143 LEU   A C   1 
ATOM   1046 O  O   . LEU   A 1 143 ? 56.62339 7.08936   28.52467  1.000 90.28153  ? 143 LEU   A O   1 
ATOM   1047 C  CB  . LEU   A 1 143 ? 56.50780 10.27916  28.36549  1.000 87.50079  ? 143 LEU   A CB  1 
ATOM   1048 C  CG  . LEU   A 1 143 ? 56.15488 11.70926  28.77591  1.000 95.16122  ? 143 LEU   A CG  1 
ATOM   1049 C  CD1 . LEU   A 1 143 ? 57.38808 12.59600  28.74494  1.000 108.16681 ? 143 LEU   A CD1 1 
ATOM   1050 C  CD2 . LEU   A 1 143 ? 55.07384 12.26573  27.86327  1.000 95.72940  ? 143 LEU   A CD2 1 
ATOM   1051 N  N   . TRP   A 1 144 ? 55.15857 7.69155   26.91450  1.000 92.94138  ? 144 TRP   A N   1 
ATOM   1052 C  CA  . TRP   A 1 144 ? 55.30508 6.45345   26.16377  1.000 97.46774  ? 144 TRP   A CA  1 
ATOM   1053 C  C   . TRP   A 1 144 ? 55.22752 6.73238   24.66939  1.000 98.67246  ? 144 TRP   A C   1 
ATOM   1054 O  O   . TRP   A 1 144 ? 54.45225 7.58492   24.22228  1.000 102.51263 ? 144 TRP   A O   1 
ATOM   1055 C  CB  . TRP   A 1 144 ? 54.22518 5.43025   26.53926  1.000 95.84619  ? 144 TRP   A CB  1 
ATOM   1056 C  CG  . TRP   A 1 144 ? 53.97369 5.28632   28.00647  1.000 91.83947  ? 144 TRP   A CG  1 
ATOM   1057 C  CD1 . TRP   A 1 144 ? 52.93664 5.81871   28.71483  1.000 87.19763  ? 144 TRP   A CD1 1 
ATOM   1058 C  CD2 . TRP   A 1 144 ? 54.76820 4.55475   28.94658  1.000 96.67521  ? 144 TRP   A CD2 1 
ATOM   1059 N  NE1 . TRP   A 1 144 ? 53.03735 5.46581   30.03856  1.000 93.24411  ? 144 TRP   A NE1 1 
ATOM   1060 C  CE2 . TRP   A 1 144 ? 54.15402 4.69004   30.20679  1.000 92.89783  ? 144 TRP   A CE2 1 
ATOM   1061 C  CE3 . TRP   A 1 144 ? 55.94011 3.80066   28.84595  1.000 101.78168 ? 144 TRP   A CE3 1 
ATOM   1062 C  CZ2 . TRP   A 1 144 ? 54.67106 4.09681   31.35623  1.000 89.53061  ? 144 TRP   A CZ2 1 
ATOM   1063 C  CZ3 . TRP   A 1 144 ? 56.45125 3.21561   29.98921  1.000 103.28956 ? 144 TRP   A CZ3 1 
ATOM   1064 C  CH2 . TRP   A 1 144 ? 55.81883 3.36766   31.22696  1.000 93.86829  ? 144 TRP   A CH2 1 
ATOM   1065 N  N   . ASP   A 1 145 ? 56.03207 5.99724   23.90589  1.000 94.11407  ? 145 ASP   A N   1 
ATOM   1066 C  CA  . ASP   A 1 145 ? 55.93751 5.98698   22.45394  1.000 96.69407  ? 145 ASP   A CA  1 
ATOM   1067 C  C   . ASP   A 1 145 ? 54.97924 4.88426   22.02339  1.000 97.70531  ? 145 ASP   A C   1 
ATOM   1068 O  O   . ASP   A 1 145 ? 55.01130 3.77343   22.56043  1.000 94.45556  ? 145 ASP   A O   1 
ATOM   1069 C  CB  . ASP   A 1 145 ? 57.31757 5.77711   21.82286  1.000 102.00338 ? 145 ASP   A CB  1 
ATOM   1070 C  CG  . ASP   A 1 145 ? 57.28886 5.83679   20.30287  1.000 105.34881 ? 145 ASP   A CG  1 
ATOM   1071 O  OD1 . ASP   A 1 145 ? 56.68799 4.94124   19.67193  1.000 103.54361 ? 145 ASP   A OD1 1 
ATOM   1072 O  OD2 . ASP   A 1 145 ? 57.87016 6.78652   19.73641  1.000 102.42592 ? 145 ASP   A OD2 1 
ATOM   1073 N  N   . VAL   A 1 146 ? 54.12221 5.20041   21.05109  1.000 100.89185 ? 146 VAL   A N   1 
ATOM   1074 C  CA  . VAL   A 1 146 ? 53.10589 4.24573   20.61636  1.000 104.65913 ? 146 VAL   A CA  1 
ATOM   1075 C  C   . VAL   A 1 146 ? 53.74982 3.06793   19.89374  1.000 107.56083 ? 146 VAL   A C   1 
ATOM   1076 O  O   . VAL   A 1 146 ? 53.43198 1.90355   20.16564  1.000 107.76252 ? 146 VAL   A O   1 
ATOM   1077 C  CB  . VAL   A 1 146 ? 52.05473 4.94509   19.73563  1.000 96.72154  ? 146 VAL   A CB  1 
ATOM   1078 C  CG1 . VAL   A 1 146 ? 51.13046 3.92105   19.09621  1.000 94.51708  ? 146 VAL   A CG1 1 
ATOM   1079 C  CG2 . VAL   A 1 146 ? 51.25466 5.94048   20.56066  1.000 97.23586  ? 146 VAL   A CG2 1 
ATOM   1080 N  N   . ASN   A 1 147 ? 54.66467 3.35169   18.96258  1.000 101.19931 ? 147 ASN   A N   1 
ATOM   1081 C  CA  . ASN   A 1 147 ? 55.29792 2.28034   18.20031  1.000 100.30926 ? 147 ASN   A CA  1 
ATOM   1082 C  C   . ASN   A 1 147 ? 56.17007 1.39621   19.08287  1.000 99.17229  ? 147 ASN   A C   1 
ATOM   1083 O  O   . ASN   A 1 147 ? 56.36822 0.21645   18.77059  1.000 101.67854 ? 147 ASN   A O   1 
ATOM   1084 C  CB  . ASN   A 1 147 ? 56.11834 2.86652   17.05192  1.000 98.04098  ? 147 ASN   A CB  1 
ATOM   1085 C  CG  . ASN   A 1 147 ? 55.26151 3.61082   16.04654  1.000 96.31075  ? 147 ASN   A CG  1 
ATOM   1086 O  OD1 . ASN   A 1 147 ? 54.70125 3.01278   15.12767  1.000 94.46616  ? 147 ASN   A OD1 1 
ATOM   1087 N  ND2 . ASN   A 1 147 ? 55.15463 4.92352   16.21679  1.000 94.27005  ? 147 ASN   A ND2 1 
ATOM   1088 N  N   . THR   A 1 148 ? 56.69733 1.94090   20.18158  1.000 93.51916  ? 148 THR   A N   1 
ATOM   1089 C  CA  . THR   A 1 148 ? 57.45481 1.11811   21.11881  1.000 95.03541  ? 148 THR   A CA  1 
ATOM   1090 C  C   . THR   A 1 148 ? 56.54143 0.14489   21.85452  1.000 105.11409 ? 148 THR   A C   1 
ATOM   1091 O  O   . THR   A 1 148 ? 56.90422 -1.01834  22.06714  1.000 110.82198 ? 148 THR   A O   1 
ATOM   1092 C  CB  . THR   A 1 148 ? 58.20626 2.00733   22.11128  1.000 85.24575  ? 148 THR   A CB  1 
ATOM   1093 O  OG1 . THR   A 1 148 ? 59.11102 2.86173   21.40053  1.000 86.74022  ? 148 THR   A OG1 1 
ATOM   1094 C  CG2 . THR   A 1 148 ? 58.99319 1.16232   23.10368  1.000 80.83187  ? 148 THR   A CG2 1 
ATOM   1095 N  N   . LEU   A 1 149 ? 55.34630 0.59948   22.23944  1.000 104.47860 ? 149 LEU   A N   1 
ATOM   1096 C  CA  . LEU   A 1 149 ? 54.41489 -0.27137  22.94801  1.000 103.55609 ? 149 LEU   A CA  1 
ATOM   1097 C  C   . LEU   A 1 149 ? 53.78516 -1.30278  22.02070  1.000 100.55298 ? 149 LEU   A C   1 
ATOM   1098 O  O   . LEU   A 1 149 ? 53.49792 -2.42540  22.45179  1.000 100.68881 ? 149 LEU   A O   1 
ATOM   1099 C  CB  . LEU   A 1 149 ? 53.32792 0.56287   23.62560  1.000 101.42091 ? 149 LEU   A CB  1 
ATOM   1100 C  CG  . LEU   A 1 149 ? 53.78691 1.52574   24.72176  1.000 94.96139  ? 149 LEU   A CG  1 
ATOM   1101 C  CD1 . LEU   A 1 149 ? 52.62076 2.36621   25.21505  1.000 94.39891  ? 149 LEU   A CD1 1 
ATOM   1102 C  CD2 . LEU   A 1 149 ? 54.42421 0.76284   25.87201  1.000 88.47357  ? 149 LEU   A CD2 1 
ATOM   1103 N  N   . THR   A 1 150 ? 53.56005 -0.94729  20.75310  1.000 96.38744  ? 150 THR   A N   1 
ATOM   1104 C  CA  . THR   A 1 150 ? 52.94573 -1.88726  19.82138  1.000 105.25379 ? 150 THR   A CA  1 
ATOM   1105 C  C   . THR   A 1 150 ? 53.87443 -3.03782  19.45633  1.000 109.43443 ? 150 THR   A C   1 
ATOM   1106 O  O   . THR   A 1 150 ? 53.39687 -4.07818  18.99127  1.000 107.21991 ? 150 THR   A O   1 
ATOM   1107 C  CB  . THR   A 1 150 ? 52.50131 -1.16701  18.54699  1.000 106.98760 ? 150 THR   A CB  1 
ATOM   1108 O  OG1 . THR   A 1 150 ? 53.61842 -0.48332  17.96624  1.000 109.49605 ? 150 THR   A OG1 1 
ATOM   1109 C  CG2 . THR   A 1 150 ? 51.39975 -0.16669  18.85449  1.000 98.09535  ? 150 THR   A CG2 1 
ATOM   1110 N  N   . ALA   A 1 151 ? 55.18144 -2.87801  19.65205  1.000 108.32624 ? 151 ALA   A N   1 
ATOM   1111 C  CA  . ALA   A 1 151 ? 56.16131 -3.92019  19.35267  1.000 112.62615 ? 151 ALA   A CA  1 
ATOM   1112 C  C   . ALA   A 1 151 ? 56.57039 -4.68770  20.60252  1.000 114.53807 ? 151 ALA   A C   1 
ATOM   1113 O  O   . ALA   A 1 151 ? 57.74100 -5.04113  20.77166  1.000 120.34211 ? 151 ALA   A O   1 
ATOM   1114 C  CB  . ALA   A 1 151 ? 57.38337 -3.31566  18.66843  1.000 108.02792 ? 151 ALA   A CB  1 
ATOM   1115 N  N   . LEU   A 1 152 ? 55.62154 -4.96023  21.49355  1.000 106.41709 ? 152 LEU   A N   1 
ATOM   1116 C  CA  . LEU   A 1 152 ? 55.88905 -5.64564  22.74862  1.000 106.26357 ? 152 LEU   A CA  1 
ATOM   1117 C  C   . LEU   A 1 152 ? 55.21934 -7.01243  22.75979  1.000 110.81455 ? 152 LEU   A C   1 
ATOM   1118 O  O   . LEU   A 1 152 ? 54.08409 -7.16499  22.29775  1.000 110.42043 ? 152 LEU   A O   1 
ATOM   1119 C  CB  . LEU   A 1 152 ? 55.39646 -4.82303  23.94136  1.000 104.88771 ? 152 LEU   A CB  1 
ATOM   1120 C  CG  . LEU   A 1 152 ? 56.11158 -3.49835  24.20772  1.000 105.41982 ? 152 LEU   A CG  1 
ATOM   1121 C  CD1 . LEU   A 1 152 ? 55.51657 -2.81368  25.42713  1.000 106.51373 ? 152 LEU   A CD1 1 
ATOM   1122 C  CD2 . LEU   A 1 152 ? 57.60412 -3.72392  24.38886  1.000 114.09364 ? 152 LEU   A CD2 1 
ATOM   1123 N  N   . THR   A 1 153 ? 55.93360 -8.00212  23.28903  1.000 118.10889 ? 153 THR   A N   1 
ATOM   1124 C  CA  . THR   A 1 153 ? 55.41304 -9.34996  23.48052  1.000 119.55815 ? 153 THR   A CA  1 
ATOM   1125 C  C   . THR   A 1 153 ? 55.84338 -9.82267  24.86473  1.000 118.58683 ? 153 THR   A C   1 
ATOM   1126 O  O   . THR   A 1 153 ? 56.31324 -9.03661  25.69349  1.000 110.83025 ? 153 THR   A O   1 
ATOM   1127 C  CB  . THR   A 1 153 ? 55.90869 -10.30075 22.38067  1.000 114.76299 ? 153 THR   A CB  1 
ATOM   1128 O  OG1 . THR   A 1 153 ? 57.34020 -10.25660 22.31775  1.000 112.82889 ? 153 THR   A OG1 1 
ATOM   1129 C  CG2 . THR   A 1 153 ? 55.33039 -9.91815  21.02470  1.000 106.68937 ? 153 THR   A CG2 1 
ATOM   1130 N  N   . ALA   A 1 154 ? 55.67862 -11.12214 25.11987  1.000 120.98596 ? 154 ALA   A N   1 
ATOM   1131 C  CA  . ALA   A 1 154 ? 56.25291 -11.71406 26.32105  1.000 121.71550 ? 154 ALA   A CA  1 
ATOM   1132 C  C   . ALA   A 1 154 ? 57.76334 -11.86247 26.21028  1.000 128.03950 ? 154 ALA   A C   1 
ATOM   1133 O  O   . ALA   A 1 154 ? 58.45007 -11.88896 27.23716  1.000 127.80405 ? 154 ALA   A O   1 
ATOM   1134 C  CB  . ALA   A 1 154 ? 55.61101 -13.07301 26.60403  1.000 109.60881 ? 154 ALA   A CB  1 
ATOM   1135 N  N   . SER   A 1 155 ? 58.29095 -11.96117 24.98905  1.000 130.40145 ? 155 SER   A N   1 
ATOM   1136 C  CA  . SER   A 1 155 ? 59.73542 -11.98341 24.78656  1.000 130.63047 ? 155 SER   A CA  1 
ATOM   1137 C  C   . SER   A 1 155 ? 60.30639 -10.56976 24.81681  1.000 135.87117 ? 155 SER   A C   1 
ATOM   1138 O  O   . SER   A 1 155 ? 61.19316 -10.26111 25.62038  1.000 138.72741 ? 155 SER   A O   1 
ATOM   1139 C  CB  . SER   A 1 155 ? 60.06910 -12.67532 23.46154  1.000 122.74556 ? 155 SER   A CB  1 
ATOM   1140 O  OG  . SER   A 1 155 ? 59.50342 -13.97359 23.40653  1.000 117.71328 ? 155 SER   A OG  1 
ATOM   1141 N  N   . ASN   A 1 156 ? 59.80468 -9.69691  23.94313  1.000 129.81464 ? 156 ASN   A N   1 
ATOM   1142 C  CA  . ASN   A 1 156 ? 60.17868 -8.28897  23.96799  1.000 127.51033 ? 156 ASN   A CA  1 
ATOM   1143 C  C   . ASN   A 1 156 ? 59.52245 -7.61589  25.16661  1.000 120.11857 ? 156 ASN   A C   1 
ATOM   1144 O  O   . ASN   A 1 156 ? 58.41877 -7.07219  25.05634  1.000 116.77937 ? 156 ASN   A O   1 
ATOM   1145 C  CB  . ASN   A 1 156 ? 59.77195 -7.59990  22.66339  1.000 125.18474 ? 156 ASN   A CB  1 
ATOM   1146 C  CG  . ASN   A 1 156 ? 60.49021 -6.28111  22.44953  1.000 121.62541 ? 156 ASN   A CG  1 
ATOM   1147 O  OD1 . ASN   A 1 156 ? 61.00356 -5.67802  23.39198  1.000 111.38575 ? 156 ASN   A OD1 1 
ATOM   1148 N  ND2 . ASN   A 1 156 ? 60.52836 -5.82555  21.20257  1.000 118.81549 ? 156 ASN   A ND2 1 
ATOM   1149 N  N   . ASN   A 1 157 ? 60.19561 -7.65064  26.31653  1.000 118.44645 ? 157 ASN   A N   1 
ATOM   1150 C  CA  . ASN   A 1 157 ? 59.62601 -7.20546  27.58593  1.000 123.74682 ? 157 ASN   A CA  1 
ATOM   1151 C  C   . ASN   A 1 157 ? 60.53202 -6.14025  28.20912  1.000 127.28784 ? 157 ASN   A C   1 
ATOM   1152 O  O   . ASN   A 1 157 ? 61.11147 -6.32971  29.27791  1.000 121.37700 ? 157 ASN   A O   1 
ATOM   1153 C  CB  . ASN   A 1 157 ? 59.43739 -8.40136  28.52067  1.000 121.95119 ? 157 ASN   A CB  1 
ATOM   1154 C  CG  . ASN   A 1 157 ? 58.47157 -8.11742  29.65436  1.000 124.13616 ? 157 ASN   A CG  1 
ATOM   1155 O  OD1 . ASN   A 1 157 ? 58.35300 -6.98481  30.12030  1.000 123.13422 ? 157 ASN   A OD1 1 
ATOM   1156 N  ND2 . ASN   A 1 157 ? 57.77423 -9.15386  30.10645  1.000 119.28649 ? 157 ASN   A ND2 1 
ATOM   1157 N  N   . THR   A 1 158 ? 60.65400 -5.00028  27.52654  1.000 129.59476 ? 158 THR   A N   1 
ATOM   1158 C  CA  . THR   A 1 158 ? 61.55186 -3.92535  27.94977  1.000 117.40107 ? 158 THR   A CA  1 
ATOM   1159 C  C   . THR   A 1 158 ? 60.87879 -2.58228  27.69388  1.000 110.91817 ? 158 THR   A C   1 
ATOM   1160 O  O   . THR   A 1 158 ? 60.78368 -2.15122  26.54030  1.000 107.62527 ? 158 THR   A O   1 
ATOM   1161 C  CB  . THR   A 1 158 ? 62.89159 -3.99680  27.21006  1.000 107.22505 ? 158 THR   A CB  1 
ATOM   1162 O  OG1 . THR   A 1 158 ? 62.65942 -4.00289  25.79583  1.000 107.90391 ? 158 THR   A OG1 1 
ATOM   1163 C  CG2 . THR   A 1 158 ? 63.67419 -5.24871  27.59888  1.000 99.78304  ? 158 THR   A CG2 1 
ATOM   1164 N  N   . VAL   A 1 159 ? 60.42975 -1.91687  28.76325  1.000 114.30250 ? 159 VAL   A N   1 
ATOM   1165 C  CA  . VAL   A 1 159 ? 59.86051 -0.57222  28.67613  1.000 117.93654 ? 159 VAL   A CA  1 
ATOM   1166 C  C   . VAL   A 1 159 ? 59.69269 0.03511   30.06946  1.000 121.60974 ? 159 VAL   A C   1 
ATOM   1167 O  O   . VAL   A 1 159 ? 58.85255 -0.41065  30.85972  1.000 125.84311 ? 159 VAL   A O   1 
ATOM   1168 C  CB  . VAL   A 1 159 ? 58.52289 -0.58495  27.90687  1.000 119.33488 ? 159 VAL   A CB  1 
ATOM   1169 C  CG1 . VAL   A 1 159 ? 57.60636 -1.70430  28.40320  1.000 111.66701 ? 159 VAL   A CG1 1 
ATOM   1170 C  CG2 . VAL   A 1 159 ? 57.83978 0.76779   27.99849  1.000 116.85259 ? 159 VAL   A CG2 1 
ATOM   1171 N  N   . THR   A 1 160 ? 60.49420 1.05685   30.38489  1.000 124.43001 ? 160 THR   A N   1 
ATOM   1172 C  CA  . THR   A 1 160 ? 60.40701 1.77732   31.64943  1.000 122.90912 ? 160 THR   A CA  1 
ATOM   1173 C  C   . THR   A 1 160 ? 59.85533 3.18175   31.40231  1.000 125.60126 ? 160 THR   A C   1 
ATOM   1174 O  O   . THR   A 1 160 ? 59.47002 3.53340   30.28333  1.000 121.58943 ? 160 THR   A O   1 
ATOM   1175 C  CB  . THR   A 1 160 ? 61.77039 1.81947   32.35331  1.000 105.77530 ? 160 THR   A CB  1 
ATOM   1176 O  OG1 . THR   A 1 160 ? 61.57903 2.06349   33.75220  1.000 97.12835  ? 160 THR   A OG1 1 
ATOM   1177 C  CG2 . THR   A 1 160 ? 62.65978 2.92111   31.77717  1.000 102.76773 ? 160 THR   A CG2 1 
ATOM   1178 N  N   . THR   A 1 161 ? 59.81801 3.99057   32.45585  1.000 122.89329 ? 161 THR   A N   1 
ATOM   1179 C  CA  . THR   A 1 161 ? 59.17792 5.29432   32.39410  1.000 121.81929 ? 161 THR   A CA  1 
ATOM   1180 C  C   . THR   A 1 161 ? 60.17512 6.41055   32.09553  1.000 119.46554 ? 161 THR   A C   1 
ATOM   1181 O  O   . THR   A 1 161 ? 61.39083 6.25794   32.23463  1.000 117.80628 ? 161 THR   A O   1 
ATOM   1182 C  CB  . THR   A 1 161 ? 58.46168 5.60487   33.70715  1.000 124.50457 ? 161 THR   A CB  1 
ATOM   1183 O  OG1 . THR   A 1 161 ? 57.97829 6.95255   33.67127  1.000 119.48111 ? 161 THR   A OG1 1 
ATOM   1184 C  CG2 . THR   A 1 161 ? 59.41883 5.44958   34.88091  1.000 120.42055 ? 161 THR   A CG2 1 
ATOM   1185 N  N   . SER   A 1 162 ? 59.62463 7.54988   31.66918  1.000 117.57421 ? 162 SER   A N   1 
ATOM   1186 C  CA  . SER   A 1 162 ? 60.33266 8.82679   31.60624  1.000 112.32479 ? 162 SER   A CA  1 
ATOM   1187 C  C   . SER   A 1 162 ? 59.48438 9.82863   32.39288  1.000 106.85019 ? 162 SER   A C   1 
ATOM   1188 O  O   . SER   A 1 162 ? 58.83676 10.71013  31.82621  1.000 109.70727 ? 162 SER   A O   1 
ATOM   1189 C  CB  . SER   A 1 162 ? 60.56032 9.27472   30.16193  1.000 109.04026 ? 162 SER   A CB  1 
ATOM   1190 O  OG  . SER   A 1 162 ? 61.29076 10.48828  30.11194  1.000 106.20113 ? 162 SER   A OG  1 
ATOM   1191 N  N   . SER   A 1 163 ? 59.49506 9.67698   33.71379  1.000 102.20520 ? 163 SER   A N   1 
ATOM   1192 C  CA  . SER   A 1 163 ? 58.47678 10.26929  34.56778  1.000 100.93930 ? 163 SER   A CA  1 
ATOM   1193 C  C   . SER   A 1 163 ? 58.67790 11.76703  34.75864  1.000 105.82944 ? 163 SER   A C   1 
ATOM   1194 O  O   . SER   A 1 163 ? 59.80285 12.27147  34.78342  1.000 104.20671 ? 163 SER   A O   1 
ATOM   1195 C  CB  . SER   A 1 163 ? 58.46495 9.57778   35.93179  1.000 103.30849 ? 163 SER   A CB  1 
ATOM   1196 O  OG  . SER   A 1 163 ? 59.71509 9.71679   36.58692  1.000 107.34862 ? 163 SER   A OG  1 
ATOM   1197 N  N   . LEU   A 1 164 ? 57.55833 12.47160  34.90417  1.000 106.90385 ? 164 LEU   A N   1 
ATOM   1198 C  CA  . LEU   A 1 164 ? 57.53583 13.87878  35.27826  1.000 103.03472 ? 164 LEU   A CA  1 
ATOM   1199 C  C   . LEU   A 1 164 ? 57.08328 13.98807  36.72872  1.000 102.07777 ? 164 LEU   A C   1 
ATOM   1200 O  O   . LEU   A 1 164 ? 56.11338 13.33627  37.13046  1.000 95.45861  ? 164 LEU   A O   1 
ATOM   1201 C  CB  . LEU   A 1 164 ? 56.59445 14.67295  34.37130  1.000 98.21701  ? 164 LEU   A CB  1 
ATOM   1202 C  CG  . LEU   A 1 164 ? 56.70946 14.43161  32.86342  1.000 97.97831  ? 164 LEU   A CG  1 
ATOM   1203 C  CD1 . LEU   A 1 164 ? 55.64643 15.21672  32.11077  1.000 96.45546  ? 164 LEU   A CD1 1 
ATOM   1204 C  CD2 . LEU   A 1 164 ? 58.09600 14.79166  32.35955  1.000 98.55081  ? 164 LEU   A CD2 1 
ATOM   1205 N  N   . SER   A 1 165 ? 57.78430 14.80375  37.51159  1.000 108.94056 ? 165 SER   A N   1 
ATOM   1206 C  CA  . SER   A 1 165 ? 57.51209 14.92785  38.93542  1.000 116.76655 ? 165 SER   A CA  1 
ATOM   1207 C  C   . SER   A 1 165 ? 57.27874 16.38739  39.29844  1.000 107.44488 ? 165 SER   A C   1 
ATOM   1208 O  O   . SER   A 1 165 ? 57.65336 17.30322  38.56160  1.000 99.17257  ? 165 SER   A O   1 
ATOM   1209 C  CB  . SER   A 1 165 ? 58.66022 14.35207  39.77741  1.000 126.93979 ? 165 SER   A CB  1 
ATOM   1210 O  OG  . SER   A 1 165 ? 59.88514 14.99809  39.47854  1.000 137.18920 ? 165 SER   A OG  1 
ATOM   1211 N  N   . GLY   A 1 166 ? 56.64809 16.59008  40.45283  1.000 98.63506  ? 166 GLY   A N   1 
ATOM   1212 C  CA  . GLY   A 1 166 ? 56.39425 17.92568  40.95218  1.000 94.06198  ? 166 GLY   A CA  1 
ATOM   1213 C  C   . GLY   A 1 166 ? 55.02567 18.09795  41.57877  1.000 91.98324  ? 166 GLY   A C   1 
ATOM   1214 O  O   . GLY   A 1 166 ? 54.82908 18.98892  42.41058  1.000 89.74030  ? 166 GLY   A O   1 
ATOM   1215 N  N   . ASN   A 1 167 ? 54.07330 17.25073  41.19232  1.000 88.29427  ? 167 ASN   A N   1 
ATOM   1216 C  CA  . ASN   A 1 167 ? 52.70094 17.37972  41.66948  1.000 81.15517  ? 167 ASN   A CA  1 
ATOM   1217 C  C   . ASN   A 1 167 ? 52.63645 17.12523  43.17002  1.000 83.68100  ? 167 ASN   A C   1 
ATOM   1218 O  O   . ASN   A 1 167 ? 53.00298 16.04379  43.64187  1.000 89.91385  ? 167 ASN   A O   1 
ATOM   1219 C  CB  . ASN   A 1 167 ? 51.78976 16.40880  40.92459  1.000 78.49409  ? 167 ASN   A CB  1 
ATOM   1220 C  CG  . ASN   A 1 167 ? 51.84177 16.59920  39.42448  1.000 83.41190  ? 167 ASN   A CG  1 
ATOM   1221 O  OD1 . ASN   A 1 167 ? 52.63683 15.96185  38.73597  1.000 85.67347  ? 167 ASN   A OD1 1 
ATOM   1222 N  ND2 . ASN   A 1 167 ? 50.99385 17.48168  38.90867  1.000 79.27440  ? 167 ASN   A ND2 1 
ATOM   1223 N  N   . LYS   A 1 168 ? 52.16537 18.11966  43.91735  1.000 85.33427  ? 168 LYS   A N   1 
ATOM   1224 C  CA  . LYS   A 1 168 ? 52.02397 18.01383  45.36179  1.000 89.58176  ? 168 LYS   A CA  1 
ATOM   1225 C  C   . LYS   A 1 168 ? 50.70088 17.38381  45.78057  1.000 84.10917  ? 168 LYS   A C   1 
ATOM   1226 O  O   . LYS   A 1 168 ? 50.38107 17.38264  46.97391  1.000 80.73799  ? 168 LYS   A O   1 
ATOM   1227 C  CB  . LYS   A 1 168 ? 52.17783 19.39530  46.00539  1.000 92.13154  ? 168 LYS   A CB  1 
ATOM   1228 C  CG  . LYS   A 1 168 ? 53.54736 20.02268  45.78231  1.000 88.00535  ? 168 LYS   A CG  1 
ATOM   1229 C  CD  . LYS   A 1 168 ? 53.59825 21.46437  46.26547  1.000 85.60357  ? 168 LYS   A CD  1 
ATOM   1230 C  CE  . LYS   A 1 168 ? 54.96119 22.08562  45.99139  1.000 77.21357  ? 168 LYS   A CE  1 
ATOM   1231 N  NZ  . LYS   A 1 168 ? 55.00516 23.53189  46.34462  1.000 61.08415  ? 168 LYS   A NZ  1 
ATOM   1232 N  N   . ASP   A 1 169 ? 49.93278 16.84934  44.83427  1.000 81.57451  ? 169 ASP   A N   1 
ATOM   1233 C  CA  . ASP   A 1 169 ? 48.68425 16.16300  45.14197  1.000 83.63323  ? 169 ASP   A CA  1 
ATOM   1234 C  C   . ASP   A 1 169 ? 48.31048 15.29172  43.94692  1.000 80.95731  ? 169 ASP   A C   1 
ATOM   1235 O  O   . ASP   A 1 169 ? 49.03039 15.23406  42.94593  1.000 76.20817  ? 169 ASP   A O   1 
ATOM   1236 C  CB  . ASP   A 1 169 ? 47.57539 17.15946  45.49304  1.000 84.50464  ? 169 ASP   A CB  1 
ATOM   1237 C  CG  . ASP   A 1 169 ? 46.59308 16.60265  46.50489  1.000 83.25786  ? 169 ASP   A CG  1 
ATOM   1238 O  OD1 . ASP   A 1 169 ? 46.22819 15.41339  46.39055  1.000 75.62133  ? 169 ASP   A OD1 1 
ATOM   1239 O  OD2 . ASP   A 1 169 ? 46.18843 17.35275  47.41764  1.000 90.23307  ? 169 ASP   A OD2 1 
ATOM   1240 N  N   . SER   A 1 170 ? 47.17059 14.61321  44.05986  1.000 74.50750  ? 170 SER   A N   1 
ATOM   1241 C  CA  . SER   A 1 170 ? 46.75537 13.65859  43.04138  1.000 64.07319  ? 170 SER   A CA  1 
ATOM   1242 C  C   . SER   A 1 170 ? 46.28650 14.36864  41.77520  1.000 65.16666  ? 170 SER   A C   1 
ATOM   1243 O  O   . SER   A 1 170 ? 45.74559 15.47588  41.81782  1.000 68.23869  ? 170 SER   A O   1 
ATOM   1244 C  CB  . SER   A 1 170 ? 45.64002 12.76201  43.57667  1.000 61.24898  ? 170 SER   A CB  1 
ATOM   1245 O  OG  . SER   A 1 170 ? 46.06918 12.03729  44.71597  1.000 63.65079  ? 170 SER   A OG  1 
ATOM   1246 N  N   . ILE   A 1 171 ? 46.48786 13.70277  40.63870  1.000 68.63201  ? 171 ILE   A N   1 
ATOM   1247 C  CA  . ILE   A 1 171 ? 46.15092 14.23542  39.32354  1.000 68.75736  ? 171 ILE   A CA  1 
ATOM   1248 C  C   . ILE   A 1 171 ? 44.78197 13.71278  38.91341  1.000 66.11974  ? 171 ILE   A C   1 
ATOM   1249 O  O   . ILE   A 1 171 ? 44.38613 12.59837  39.27560  1.000 70.64229  ? 171 ILE   A O   1 
ATOM   1250 C  CB  . ILE   A 1 171 ? 47.22791 13.84964  38.28689  1.000 66.70736  ? 171 ILE   A CB  1 
ATOM   1251 C  CG1 . ILE   A 1 171 ? 48.62428 14.00925  38.89077  1.000 74.57491  ? 171 ILE   A CG1 1 
ATOM   1252 C  CG2 . ILE   A 1 171 ? 47.09500 14.68997  37.02617  1.000 70.13663  ? 171 ILE   A CG2 1 
ATOM   1253 C  CD1 . ILE   A 1 171 ? 49.72938 13.45063  38.02584  1.000 78.34756  ? 171 ILE   A CD1 1 
ATOM   1254 N  N   . TYR   A 1 172 ? 44.04451 14.52232  38.14641  1.000 65.55460  ? 172 TYR   A N   1 
ATOM   1255 C  CA  . TYR   A 1 172 ? 42.73489 14.11894  37.65214  1.000 64.20799  ? 172 TYR   A CA  1 
ATOM   1256 C  C   . TYR   A 1 172 ? 42.52257 14.37397  36.16710  1.000 65.74077  ? 172 TYR   A C   1 
ATOM   1257 O  O   . TYR   A 1 172 ? 41.49080 13.95029  35.63433  1.000 66.64276  ? 172 TYR   A O   1 
ATOM   1258 C  CB  . TYR   A 1 172 ? 41.61917 14.82754  38.43683  1.000 66.60831  ? 172 TYR   A CB  1 
ATOM   1259 C  CG  . TYR   A 1 172 ? 41.13480 14.06141  39.64766  1.000 63.05276  ? 172 TYR   A CG  1 
ATOM   1260 C  CD1 . TYR   A 1 172 ? 41.85762 14.06603  40.83318  1.000 65.63704  ? 172 TYR   A CD1 1 
ATOM   1261 C  CD2 . TYR   A 1 172 ? 39.94990 13.33781  39.60603  1.000 66.63276  ? 172 TYR   A CD2 1 
ATOM   1262 C  CE1 . TYR   A 1 172 ? 41.41630 13.36739  41.94246  1.000 67.51114  ? 172 TYR   A CE1 1 
ATOM   1263 C  CE2 . TYR   A 1 172 ? 39.50016 12.63706  40.71025  1.000 76.63964  ? 172 TYR   A CE2 1 
ATOM   1264 C  CZ  . TYR   A 1 172 ? 40.23718 12.65574  41.87568  1.000 71.60644  ? 172 TYR   A CZ  1 
ATOM   1265 O  OH  . TYR   A 1 172 ? 39.79467 11.96014  42.97795  1.000 66.39663  ? 172 TYR   A OH  1 
ATOM   1266 N  N   . SER   A 1 173 ? 43.44999 15.04165  35.48441  1.000 62.56191  ? 173 SER   A N   1 
ATOM   1267 C  CA  . SER   A 1 173 ? 43.29525 15.32577  34.06594  1.000 60.66741  ? 173 SER   A CA  1 
ATOM   1268 C  C   . SER   A 1 173 ? 44.67055 15.48196  33.43478  1.000 63.35824  ? 173 SER   A C   1 
ATOM   1269 O  O   . SER   A 1 173 ? 45.67233 15.69396  34.12306  1.000 67.07923  ? 173 SER   A O   1 
ATOM   1270 C  CB  . SER   A 1 173 ? 42.44701 16.58201  33.83307  1.000 70.71242  ? 173 SER   A CB  1 
ATOM   1271 O  OG  . SER   A 1 173 ? 42.98448 17.69629  34.52422  1.000 68.13552  ? 173 SER   A OG  1 
ATOM   1272 N  N   . LEU   A 1 174 ? 44.70414 15.37532  32.10841  1.000 62.16513  ? 174 LEU   A N   1 
ATOM   1273 C  CA  . LEU   A 1 174 ? 45.94960 15.45993  31.35981  1.000 63.72152  ? 174 LEU   A CA  1 
ATOM   1274 C  C   . LEU   A 1 174 ? 45.62069 15.78239  29.90962  1.000 66.20269  ? 174 LEU   A C   1 
ATOM   1275 O  O   . LEU   A 1 174 ? 44.58570 15.35832  29.38847  1.000 67.94683  ? 174 LEU   A O   1 
ATOM   1276 C  CB  . LEU   A 1 174 ? 46.74638 14.15350  31.45657  1.000 66.41875  ? 174 LEU   A CB  1 
ATOM   1277 C  CG  . LEU   A 1 174 ? 48.23960 14.20889  31.13274  1.000 66.52227  ? 174 LEU   A CG  1 
ATOM   1278 C  CD1 . LEU   A 1 174 ? 48.97891 15.05154  32.15934  1.000 67.79423  ? 174 LEU   A CD1 1 
ATOM   1279 C  CD2 . LEU   A 1 174 ? 48.82325 12.80576  31.06295  1.000 65.24170  ? 174 LEU   A CD2 1 
ATOM   1280 N  N   . ALA   A 1 175 ? 46.50969 16.53558  29.26443  1.000 66.59321  ? 175 ALA   A N   1 
ATOM   1281 C  CA  . ALA   A 1 175 ? 46.27774 16.94719  27.88701  1.000 67.34551  ? 175 ALA   A CA  1 
ATOM   1282 C  C   . ALA   A 1 175 ? 47.59859 17.32765  27.23407  1.000 69.91635  ? 175 ALA   A C   1 
ATOM   1283 O  O   . ALA   A 1 175 ? 48.51834 17.81540  27.89637  1.000 65.70997  ? 175 ALA   A O   1 
ATOM   1284 C  CB  . ALA   A 1 175 ? 45.29274 18.11947  27.81128  1.000 62.24384  ? 175 ALA   A CB  1 
ATOM   1285 N  N   . MET   A 1 176 ? 47.67516 17.09619  25.92413  1.000 75.35116  ? 176 MET   A N   1 
ATOM   1286 C  CA  . MET   A 1 176 ? 48.80961 17.50133  25.10791  1.000 76.15739  ? 176 MET   A CA  1 
ATOM   1287 C  C   . MET   A 1 176 ? 48.30687 18.16013  23.83249  1.000 74.67844  ? 176 MET   A C   1 
ATOM   1288 O  O   . MET   A 1 176 ? 47.20579 17.86972  23.35690  1.000 73.30927  ? 176 MET   A O   1 
ATOM   1289 C  CB  . MET   A 1 176 ? 49.71440 16.31421  24.74228  1.000 83.17487  ? 176 MET   A CB  1 
ATOM   1290 C  CG  . MET   A 1 176 ? 50.64008 15.86200  25.85376  1.000 84.80191  ? 176 MET   A CG  1 
ATOM   1291 S  SD  . MET   A 1 176 ? 51.94802 14.76589  25.26910  1.000 106.54777 ? 176 MET   A SD  1 
ATOM   1292 C  CE  . MET   A 1 176 ? 50.98706 13.40077  24.62280  1.000 94.69969  ? 176 MET   A CE  1 
ATOM   1293 N  N   . ASN   A 1 177 ? 49.12644 19.05129  23.28131  1.000 75.59447  ? 177 ASN   A N   1 
ATOM   1294 C  CA  . ASN   A 1 177 ? 48.79584 19.67363  22.01077  1.000 80.09145  ? 177 ASN   A CA  1 
ATOM   1295 C  C   . ASN   A 1 177 ? 48.99176 18.67583  20.86961  1.000 89.36970  ? 177 ASN   A C   1 
ATOM   1296 O  O   . ASN   A 1 177 ? 49.56247 17.59422  21.04025  1.000 90.51264  ? 177 ASN   A O   1 
ATOM   1297 C  CB  . ASN   A 1 177 ? 49.64455 20.92580  21.78925  1.000 83.20625  ? 177 ASN   A CB  1 
ATOM   1298 C  CG  . ASN   A 1 177 ? 51.13167 20.64612  21.87584  1.000 86.10888  ? 177 ASN   A CG  1 
ATOM   1299 O  OD1 . ASN   A 1 177 ? 51.55784 19.68453  22.51517  1.000 87.76713  ? 177 ASN   A OD1 1 
ATOM   1300 N  ND2 . ASN   A 1 177 ? 51.93120 21.49130  21.23518  1.000 83.60918  ? 177 ASN   A ND2 1 
ATOM   1301 N  N   . GLN   A 1 178 ? 48.50053 19.05267  19.68624  1.000 92.04087  ? 178 GLN   A N   1 
ATOM   1302 C  CA  . GLN   A 1 178 ? 48.58347 18.15660  18.53667  1.000 90.91205  ? 178 GLN   A CA  1 
ATOM   1303 C  C   . GLN   A 1 178 ? 50.03041 17.91205  18.12754  1.000 92.20494  ? 178 GLN   A C   1 
ATOM   1304 O  O   . GLN   A 1 178 ? 50.41267 16.77713  17.81847  1.000 92.33289  ? 178 GLN   A O   1 
ATOM   1305 C  CB  . GLN   A 1 178 ? 47.78556 18.72672  17.36463  1.000 87.75818  ? 178 GLN   A CB  1 
ATOM   1306 C  CG  . GLN   A 1 178 ? 47.77217 17.82948  16.13755  1.000 92.36845  ? 178 GLN   A CG  1 
ATOM   1307 C  CD  . GLN   A 1 178 ? 47.10536 18.48199  14.94377  1.000 103.62086 ? 178 GLN   A CD  1 
ATOM   1308 O  OE1 . GLN   A 1 178 ? 46.76263 19.66382  14.97863  1.000 106.15980 ? 178 GLN   A OE1 1 
ATOM   1309 N  NE2 . GLN   A 1 178 ? 46.91822 17.71295  13.87703  1.000 100.23577 ? 178 GLN   A NE2 1 
ATOM   1310 N  N   . LEU   A 1 179 ? 50.85154 18.96472  18.12076  1.000 95.27444  ? 179 LEU   A N   1 
ATOM   1311 C  CA  . LEU   A 1 179 ? 52.25405 18.81330  17.75274  1.000 95.85013  ? 179 LEU   A CA  1 
ATOM   1312 C  C   . LEU   A 1 179 ? 53.04615 18.03058  18.79116  1.000 95.93777  ? 179 LEU   A C   1 
ATOM   1313 O  O   . LEU   A 1 179 ? 54.09359 17.46747  18.45632  1.000 101.93044 ? 179 LEU   A O   1 
ATOM   1314 C  CB  . LEU   A 1 179 ? 52.89505 20.18574  17.53914  1.000 95.85003  ? 179 LEU   A CB  1 
ATOM   1315 C  CG  . LEU   A 1 179 ? 52.34388 21.02856  16.38734  1.000 97.36914  ? 179 LEU   A CG  1 
ATOM   1316 C  CD1 . LEU   A 1 179 ? 53.06116 22.36745  16.31283  1.000 90.19099  ? 179 LEU   A CD1 1 
ATOM   1317 C  CD2 . LEU   A 1 179 ? 52.46209 20.28008  15.06855  1.000 94.34859  ? 179 LEU   A CD2 1 
ATOM   1318 N  N   . GLY   A 1 180 ? 52.57570 17.98129  20.03271  1.000 93.09064  ? 180 GLY   A N   1 
ATOM   1319 C  CA  . GLY   A 1 180 ? 53.28162 17.25496  21.07063  1.000 96.52976  ? 180 GLY   A CA  1 
ATOM   1320 C  C   . GLY   A 1 180 ? 54.47736 17.98365  21.64018  1.000 95.85109  ? 180 GLY   A C   1 
ATOM   1321 O  O   . GLY   A 1 180 ? 55.52654 17.36676  21.86496  1.000 96.08506  ? 180 GLY   A O   1 
ATOM   1322 N  N   . THR   A 1 181 ? 54.35023 19.28944  21.88424  1.000 92.81204  ? 181 THR   A N   1 
ATOM   1323 C  CA  . THR   A 1 181 ? 55.44682 20.08836  22.41008  1.000 95.12225  ? 181 THR   A CA  1 
ATOM   1324 C  C   . THR   A 1 181 ? 55.21322 20.59770  23.82442  1.000 93.00630  ? 181 THR   A C   1 
ATOM   1325 O  O   . THR   A 1 181 ? 56.18018 20.98351  24.48831  1.000 90.74026  ? 181 THR   A O   1 
ATOM   1326 C  CB  . THR   A 1 181 ? 55.71877 21.29127  21.49367  1.000 91.43176  ? 181 THR   A CB  1 
ATOM   1327 O  OG1 . THR   A 1 181 ? 54.55089 22.11938  21.42859  1.000 83.75991  ? 181 THR   A OG1 1 
ATOM   1328 C  CG2 . THR   A 1 181 ? 56.07942 20.82192  20.09196  1.000 84.02535  ? 181 THR   A CG2 1 
ATOM   1329 N  N   . ILE   A 1 182 ? 53.96851 20.61172  24.29684  1.000 88.12233  ? 182 ILE   A N   1 
ATOM   1330 C  CA  . ILE   A 1 182 ? 53.62521 21.10644  25.62584  1.000 82.49852  ? 182 ILE   A CA  1 
ATOM   1331 C  C   . ILE   A 1 182 ? 52.62830 20.14288  26.25543  1.000 85.42318  ? 182 ILE   A C   1 
ATOM   1332 O  O   . ILE   A 1 182 ? 51.68382 19.69588  25.59587  1.000 83.59947  ? 182 ILE   A O   1 
ATOM   1333 C  CB  . ILE   A 1 182 ? 53.03755 22.53431  25.56746  1.000 90.02777  ? 182 ILE   A CB  1 
ATOM   1334 C  CG1 . ILE   A 1 182 ? 54.04461 23.51980  24.96790  1.000 97.53716  ? 182 ILE   A CG1 1 
ATOM   1335 C  CG2 . ILE   A 1 182 ? 52.60299 22.99626  26.94961  1.000 89.87521  ? 182 ILE   A CG2 1 
ATOM   1336 C  CD1 . ILE   A 1 182 ? 55.26403 23.75278  25.83028  1.000 97.99241  ? 182 ILE   A CD1 1 
ATOM   1337 N  N   . ILE   A 1 183 ? 52.83739 19.81804  27.53231  1.000 88.51806  ? 183 ILE   A N   1 
ATOM   1338 C  CA  . ILE   A 1 183 ? 51.90055 18.98748  28.27909  1.000 84.88806  ? 183 ILE   A CA  1 
ATOM   1339 C  C   . ILE   A 1 183 ? 51.50992 19.72413  29.55342  1.000 87.10624  ? 183 ILE   A C   1 
ATOM   1340 O  O   . ILE   A 1 183 ? 52.29823 20.48970  30.11590  1.000 90.49922  ? 183 ILE   A O   1 
ATOM   1341 C  CB  . ILE   A 1 183 ? 52.48671 17.58866  28.59453  1.000 85.75346  ? 183 ILE   A CB  1 
ATOM   1342 C  CG1 . ILE   A 1 183 ? 51.42047 16.67135  29.19878  1.000 82.54413  ? 183 ILE   A CG1 1 
ATOM   1343 C  CG2 . ILE   A 1 183 ? 53.67992 17.69446  29.52662  1.000 90.28332  ? 183 ILE   A CG2 1 
ATOM   1344 C  CD1 . ILE   A 1 183 ? 51.87659 15.23952  29.37664  1.000 78.69791  ? 183 ILE   A CD1 1 
ATOM   1345 N  N   . VAL   A 1 184 ? 50.27428 19.50480  29.99913  1.000 81.89265  ? 184 VAL   A N   1 
ATOM   1346 C  CA  . VAL   A 1 184 ? 49.73905 20.16555  31.18456  1.000 77.29767  ? 184 VAL   A CA  1 
ATOM   1347 C  C   . VAL   A 1 184 ? 49.00390 19.13438  32.03111  1.000 71.03369  ? 184 VAL   A C   1 
ATOM   1348 O  O   . VAL   A 1 184 ? 48.36391 18.21939  31.50042  1.000 65.06086  ? 184 VAL   A O   1 
ATOM   1349 C  CB  . VAL   A 1 184 ? 48.81427 21.34435  30.80516  1.000 72.93294  ? 184 VAL   A CB  1 
ATOM   1350 C  CG1 . VAL   A 1 184 ? 47.62627 20.85949  29.98325  1.000 71.84114  ? 184 VAL   A CG1 1 
ATOM   1351 C  CG2 . VAL   A 1 184 ? 48.35175 22.09486  32.04755  1.000 76.71675  ? 184 VAL   A CG2 1 
ATOM   1352 N  N   . SER   A 1 185 ? 49.10905 19.27605  33.35163  1.000 74.71727  ? 185 SER   A N   1 
ATOM   1353 C  CA  . SER   A 1 185 ? 48.45908 18.38283  34.29901  1.000 75.10651  ? 185 SER   A CA  1 
ATOM   1354 C  C   . SER   A 1 185 ? 47.59874 19.19646  35.25334  1.000 75.81373  ? 185 SER   A C   1 
ATOM   1355 O  O   . SER   A 1 185 ? 48.04482 20.22680  35.77700  1.000 77.96321  ? 185 SER   A O   1 
ATOM   1356 C  CB  . SER   A 1 185 ? 49.48596 17.56617  35.08783  1.000 76.88317  ? 185 SER   A CB  1 
ATOM   1357 O  OG  . SER   A 1 185 ? 50.11371 18.36268  36.07847  1.000 75.04389  ? 185 SER   A OG  1 
ATOM   1358 N  N   . GLY   A 1 186 ? 46.37289 18.72781  35.47122  1.000 67.52322  ? 186 GLY   A N   1 
ATOM   1359 C  CA  . GLY   A 1 186 ? 45.45987 19.31488  36.43608  1.000 65.24392  ? 186 GLY   A CA  1 
ATOM   1360 C  C   . GLY   A 1 186 ? 45.28057 18.38210  37.61937  1.000 65.26322  ? 186 GLY   A C   1 
ATOM   1361 O  O   . GLY   A 1 186 ? 45.08000 17.17510  37.45099  1.000 65.30012  ? 186 GLY   A O   1 
ATOM   1362 N  N   . SER   A 1 187 ? 45.35184 18.95631  38.81659  1.000 64.44642  ? 187 SER   A N   1 
ATOM   1363 C  CA  . SER   A 1 187 ? 45.36648 18.18783  40.04916  1.000 70.01044  ? 187 SER   A CA  1 
ATOM   1364 C  C   . SER   A 1 187 ? 44.33630 18.74427  41.02107  1.000 66.51362  ? 187 SER   A C   1 
ATOM   1365 O  O   . SER   A 1 187 ? 43.72818 19.79298  40.79025  1.000 69.21219  ? 187 SER   A O   1 
ATOM   1366 C  CB  . SER   A 1 187 ? 46.76028 18.20942  40.69322  1.000 73.93277  ? 187 SER   A CB  1 
ATOM   1367 O  OG  . SER   A 1 187 ? 47.76227 17.85023  39.75824  1.000 89.04793  ? 187 SER   A OG  1 
ATOM   1368 N  N   . THR   A 1 188 ? 44.14374 18.01900  42.12473  1.000 65.78430  ? 188 THR   A N   1 
ATOM   1369 C  CA  . THR   A 1 188 ? 43.43768 18.57594  43.27164  1.000 67.01118  ? 188 THR   A CA  1 
ATOM   1370 C  C   . THR   A 1 188 ? 44.26203 19.63405  43.98791  1.000 72.10665  ? 188 THR   A C   1 
ATOM   1371 O  O   . THR   A 1 188 ? 43.77216 20.24416  44.94505  1.000 72.00695  ? 188 THR   A O   1 
ATOM   1372 C  CB  . THR   A 1 188 ? 43.05323 17.46733  44.25373  1.000 68.14570  ? 188 THR   A CB  1 
ATOM   1373 O  OG1 . THR   A 1 188 ? 44.23687 16.82173  44.73514  1.000 76.39309  ? 188 THR   A OG1 1 
ATOM   1374 C  CG2 . THR   A 1 188 ? 42.16877 16.43650  43.57480  1.000 77.26468  ? 188 THR   A CG2 1 
ATOM   1375 N  N   . GLU   A 1 189 ? 45.50192 19.85076  43.54314  1.000 73.85565  ? 189 GLU   A N   1 
ATOM   1376 C  CA  . GLU   A 1 189 ? 46.36082 20.91853  44.03471  1.000 76.30786  ? 189 GLU   A CA  1 
ATOM   1377 C  C   . GLU   A 1 189 ? 45.86068 22.30148  43.63424  1.000 73.05191  ? 189 GLU   A C   1 
ATOM   1378 O  O   . GLU   A 1 189 ? 46.44074 23.30134  44.07210  1.000 76.33693  ? 189 GLU   A O   1 
ATOM   1379 C  CB  . GLU   A 1 189 ? 47.78285 20.69581  43.50901  1.000 75.79917  ? 189 GLU   A CB  1 
ATOM   1380 C  CG  . GLU   A 1 189 ? 48.88124 21.45581  44.23329  1.000 83.04378  ? 189 GLU   A CG  1 
ATOM   1381 C  CD  . GLU   A 1 189 ? 50.24249 21.23148  43.60442  1.000 82.84702  ? 189 GLU   A CD  1 
ATOM   1382 O  OE1 . GLU   A 1 189 ? 50.36557 20.31065  42.76902  1.000 81.47561  ? 189 GLU   A OE1 1 
ATOM   1383 O  OE2 . GLU   A 1 189 ? 51.18706 21.97631  43.94037  1.000 82.13176  ? 189 GLU   A OE2 1 
ATOM   1384 N  N   . LYS   A 1 190 ? 44.80806 22.37811  42.81594  1.000 69.86082  ? 190 LYS   A N   1 
ATOM   1385 C  CA  . LYS   A 1 190 ? 44.21910 23.63222  42.34800  1.000 70.32323  ? 190 LYS   A CA  1 
ATOM   1386 C  C   . LYS   A 1 190 ? 45.19234 24.44646  41.50199  1.000 76.19612  ? 190 LYS   A C   1 
ATOM   1387 O  O   . LYS   A 1 190 ? 45.01485 25.65823  41.33781  1.000 84.08446  ? 190 LYS   A O   1 
ATOM   1388 C  CB  . LYS   A 1 190 ? 43.70190 24.47549  43.52035  1.000 69.94241  ? 190 LYS   A CB  1 
ATOM   1389 C  CG  . LYS   A 1 190 ? 42.81709 23.70517  44.48935  1.000 75.62794  ? 190 LYS   A CG  1 
ATOM   1390 C  CD  . LYS   A 1 190 ? 42.68667 24.42960  45.81970  1.000 74.40841  ? 190 LYS   A CD  1 
ATOM   1391 C  CE  . LYS   A 1 190 ? 41.94755 23.57946  46.84304  1.000 80.61643  ? 190 LYS   A CE  1 
ATOM   1392 N  NZ  . LYS   A 1 190 ? 41.93360 24.22149  48.18714  1.000 78.43743  ? 190 LYS   A NZ  1 
ATOM   1393 N  N   . VAL   A 1 191 ? 46.21770 23.79718  40.95375  1.000 72.56098  ? 191 VAL   A N   1 
ATOM   1394 C  CA  . VAL   A 1 191 ? 47.25668 24.46004  40.17266  1.000 73.92704  ? 191 VAL   A CA  1 
ATOM   1395 C  C   . VAL   A 1 191 ? 47.55027 23.61240  38.94341  1.000 70.70849  ? 191 VAL   A C   1 
ATOM   1396 O  O   . VAL   A 1 191 ? 47.70881 22.39149  39.04937  1.000 83.78134  ? 191 VAL   A O   1 
ATOM   1397 C  CB  . VAL   A 1 191 ? 48.54023 24.67815  41.00067  1.000 84.26047  ? 191 VAL   A CB  1 
ATOM   1398 C  CG1 . VAL   A 1 191 ? 49.71982 25.01116  40.09749  1.000 80.27640  ? 191 VAL   A CG1 1 
ATOM   1399 C  CG2 . VAL   A 1 191 ? 48.32959 25.77997  42.03092  1.000 89.48341  ? 191 VAL   A CG2 1 
ATOM   1400 N  N   . LEU   A 1 192 ? 47.61612 24.25454  37.77898  1.000 69.42677  ? 192 LEU   A N   1 
ATOM   1401 C  CA  . LEU   A 1 192 ? 47.98925 23.57298  36.54687  1.000 78.27424  ? 192 LEU   A CA  1 
ATOM   1402 C  C   . LEU   A 1 192 ? 49.50631 23.53812  36.43099  1.000 82.97648  ? 192 LEU   A C   1 
ATOM   1403 O  O   . LEU   A 1 192 ? 50.16152 24.58081  36.49894  1.000 87.34003  ? 192 LEU   A O   1 
ATOM   1404 C  CB  . LEU   A 1 192 ? 47.38590 24.27073  35.32788  1.000 73.07932  ? 192 LEU   A CB  1 
ATOM   1405 C  CG  . LEU   A 1 192 ? 45.96231 23.88884  34.92355  1.000 72.97712  ? 192 LEU   A CG  1 
ATOM   1406 C  CD1 . LEU   A 1 192 ? 44.93832 24.49130  35.87199  1.000 75.67959  ? 192 LEU   A CD1 1 
ATOM   1407 C  CD2 . LEU   A 1 192 ? 45.70451 24.32203  33.49294  1.000 69.00400  ? 192 LEU   A CD2 1 
ATOM   1408 N  N   . ARG   A 1 193 ? 50.06536 22.34583  36.25446  1.000 81.30498  ? 193 ARG   A N   1 
ATOM   1409 C  CA  . ARG   A 1 193 ? 51.51240 22.18619  36.15790  1.000 80.16145  ? 193 ARG   A CA  1 
ATOM   1410 C  C   . ARG   A 1 193 ? 51.87837 21.83140  34.72390  1.000 78.43321  ? 193 ARG   A C   1 
ATOM   1411 O  O   . ARG   A 1 193 ? 51.38402 20.83675  34.18404  1.000 80.35480  ? 193 ARG   A O   1 
ATOM   1412 C  CB  . ARG   A 1 193 ? 52.01300 21.12334  37.13498  1.000 80.30351  ? 193 ARG   A CB  1 
ATOM   1413 C  CG  . ARG   A 1 193 ? 52.02996 21.59382  38.58108  1.000 71.43090  ? 193 ARG   A CG  1 
ATOM   1414 C  CD  . ARG   A 1 193 ? 52.62064 20.54783  39.50831  1.000 75.24992  ? 193 ARG   A CD  1 
ATOM   1415 N  NE  . ARG   A 1 193 ? 52.85603 21.08362  40.84377  1.000 74.45446  ? 193 ARG   A NE  1 
ATOM   1416 C  CZ  . ARG   A 1 193 ? 53.99525 21.63633  41.23765  1.000 77.92220  ? 193 ARG   A CZ  1 
ATOM   1417 N  NH1 . ARG   A 1 193 ? 55.03347 21.73434  40.42355  1.000 84.55766  ? 193 ARG   A NH1 1 
ATOM   1418 N  NH2 . ARG   A 1 193 ? 54.09694 22.09828  42.48082  1.000 74.04479  ? 193 ARG   A NH2 1 
ATOM   1419 N  N   . VAL   A 1 194 ? 52.73863 22.64198  34.10824  1.000 78.51977  ? 194 VAL   A N   1 
ATOM   1420 C  CA  . VAL   A 1 194 ? 53.08626 22.48963  32.70021  1.000 85.78213  ? 194 VAL   A CA  1 
ATOM   1421 C  C   . VAL   A 1 194 ? 54.49565 21.92464  32.58586  1.000 94.23698  ? 194 VAL   A C   1 
ATOM   1422 O  O   . VAL   A 1 194 ? 55.40801 22.34529  33.30712  1.000 98.83256  ? 194 VAL   A O   1 
ATOM   1423 C  CB  . VAL   A 1 194 ? 52.96126 23.82893  31.94768  1.000 85.74460  ? 194 VAL   A CB  1 
ATOM   1424 C  CG1 . VAL   A 1 194 ? 53.33214 23.66005  30.48346  1.000 84.50328  ? 194 VAL   A CG1 1 
ATOM   1425 C  CG2 . VAL   A 1 194 ? 51.54725 24.37352  32.08073  1.000 86.83414  ? 194 VAL   A CG2 1 
ATOM   1426 N  N   . TRP   A 1 195 ? 54.66661 20.96562  31.67696  1.000 94.15588  ? 195 TRP   A N   1 
ATOM   1427 C  CA  . TRP   A 1 195 ? 55.95351 20.35019  31.39558  1.000 94.25446  ? 195 TRP   A CA  1 
ATOM   1428 C  C   . TRP   A 1 195 ? 56.19470 20.31734  29.89158  1.000 88.56254  ? 195 TRP   A C   1 
ATOM   1429 O  O   . TRP   A 1 195 ? 55.26579 20.42020  29.08218  1.000 83.59791  ? 195 TRP   A O   1 
ATOM   1430 C  CB  . TRP   A 1 195 ? 56.04082 18.91956  31.95036  1.000 95.39672  ? 195 TRP   A CB  1 
ATOM   1431 C  CG  . TRP   A 1 195 ? 56.23458 18.83023  33.43063  1.000 94.27146  ? 195 TRP   A CG  1 
ATOM   1432 C  CD1 . TRP   A 1 195 ? 57.41006 18.95153  34.11047  1.000 101.99245 ? 195 TRP   A CD1 1 
ATOM   1433 C  CD2 . TRP   A 1 195 ? 55.22640 18.57513  34.41511  1.000 89.62119  ? 195 TRP   A CD2 1 
ATOM   1434 N  NE1 . TRP   A 1 195 ? 57.19596 18.80093  35.45887  1.000 103.35535 ? 195 TRP   A NE1 1 
ATOM   1435 C  CE2 . TRP   A 1 195 ? 55.86311 18.56763  35.67215  1.000 96.93114  ? 195 TRP   A CE2 1 
ATOM   1436 C  CE3 . TRP   A 1 195 ? 53.84690 18.35833  34.35661  1.000 87.13983  ? 195 TRP   A CE3 1 
ATOM   1437 C  CZ2 . TRP   A 1 195 ? 55.16820 18.35194  36.85953  1.000 94.74587  ? 195 TRP   A CZ2 1 
ATOM   1438 C  CZ3 . TRP   A 1 195 ? 53.15947 18.14372  35.53626  1.000 91.30280  ? 195 TRP   A CZ3 1 
ATOM   1439 C  CH2 . TRP   A 1 195 ? 53.82046 18.14189  36.77076  1.000 92.05278  ? 195 TRP   A CH2 1 
ATOM   1440 N  N   . ASP   A 1 196 ? 57.47012 20.16761  29.53048  1.000 89.10145  ? 196 ASP   A N   1 
ATOM   1441 C  CA  . ASP   A 1 196 ? 57.87077 19.94149  28.15101  1.000 91.76584  ? 196 ASP   A CA  1 
ATOM   1442 C  C   . ASP   A 1 196 ? 58.02299 18.44309  27.94380  1.000 94.40274  ? 196 ASP   A C   1 
ATOM   1443 O  O   . ASP   A 1 196 ? 58.93182 17.83582  28.53334  1.000 91.52493  ? 196 ASP   A O   1 
ATOM   1444 C  CB  . ASP   A 1 196 ? 59.18416 20.66066  27.84567  1.000 95.61798  ? 196 ASP   A CB  1 
ATOM   1445 C  CG  . ASP   A 1 196 ? 59.50195 20.70746  26.35720  1.000 95.89921  ? 196 ASP   A CG  1 
ATOM   1446 O  OD1 . ASP   A 1 196 ? 58.95637 19.88639  25.59072  1.000 92.85220  ? 196 ASP   A OD1 1 
ATOM   1447 O  OD2 . ASP   A 1 196 ? 60.31059 21.57087  25.95566  1.000 93.09507  ? 196 ASP   A OD2 1 
ATOM   1448 N  N   . PRO   A 1 197 ? 57.17536 17.80042  27.13423  1.000 96.78921  ? 197 PRO   A N   1 
ATOM   1449 C  CA  . PRO   A 1 197 ? 57.28421 16.34216  26.96596  1.000 98.95775  ? 197 PRO   A CA  1 
ATOM   1450 C  C   . PRO   A 1 197 ? 58.56606 15.89766  26.28392  1.000 101.02438 ? 197 PRO   A C   1 
ATOM   1451 O  O   . PRO   A 1 197 ? 58.93136 14.72116  26.39996  1.000 104.64277 ? 197 PRO   A O   1 
ATOM   1452 C  CB  . PRO   A 1 197 ? 56.05306 15.99363  26.11861  1.000 97.11148  ? 197 PRO   A CB  1 
ATOM   1453 C  CG  . PRO   A 1 197 ? 55.72932 17.26001  25.39130  1.000 95.61720  ? 197 PRO   A CG  1 
ATOM   1454 C  CD  . PRO   A 1 197 ? 56.07264 18.37030  26.34312  1.000 95.39204  ? 197 PRO   A CD  1 
ATOM   1455 N  N   . ARG   A 1 198 ? 59.25984 16.79323  25.58091  1.000 98.56373  ? 198 ARG   A N   1 
ATOM   1456 C  CA  . ARG   A 1 198 ? 60.49340 16.41519  24.90098  1.000 98.84273  ? 198 ARG   A CA  1 
ATOM   1457 C  C   . ARG   A 1 198 ? 61.67522 16.39420  25.86328  1.000 98.50760  ? 198 ARG   A C   1 
ATOM   1458 O  O   . ARG   A 1 198 ? 62.45885 15.43852  25.87591  1.000 104.57010 ? 198 ARG   A O   1 
ATOM   1459 C  CB  . ARG   A 1 198 ? 60.76624 17.37630  23.74377  1.000 96.81685  ? 198 ARG   A CB  1 
ATOM   1460 C  CG  . ARG   A 1 198 ? 59.64521 17.46241  22.72349  1.000 90.51532  ? 198 ARG   A CG  1 
ATOM   1461 C  CD  . ARG   A 1 198 ? 59.73500 18.76205  21.94568  1.000 93.15715  ? 198 ARG   A CD  1 
ATOM   1462 N  NE  . ARG   A 1 198 ? 59.57318 19.91671  22.82127  1.000 89.68028  ? 198 ARG   A NE  1 
ATOM   1463 C  CZ  . ARG   A 1 198 ? 59.82285 21.16953  22.46639  1.000 87.85938  ? 198 ARG   A CZ  1 
ATOM   1464 N  NH1 . ARG   A 1 198 ? 60.26614 21.47016  21.25678  1.000 91.31122  ? 198 ARG   A NH1 1 
ATOM   1465 N  NH2 . ARG   A 1 198 ? 59.62652 22.14504  23.34889  1.000 85.16805  ? 198 ARG   A NH2 1 
ATOM   1466 N  N   . THR   A 1 199 ? 61.81700 17.44002  26.67731  1.000 92.56006  ? 199 THR   A N   1 
ATOM   1467 C  CA  . THR   A 1 199 ? 62.95710 17.58067  27.57209  1.000 96.61915  ? 199 THR   A CA  1 
ATOM   1468 C  C   . THR   A 1 199 ? 62.65878 17.16072  29.00509  1.000 103.11458 ? 199 THR   A C   1 
ATOM   1469 O  O   . THR   A 1 199 ? 63.60066 16.99032  29.78719  1.000 111.33449 ? 199 THR   A O   1 
ATOM   1470 C  CB  . THR   A 1 199 ? 63.45627 19.03111  27.57039  1.000 96.68180  ? 199 THR   A CB  1 
ATOM   1471 O  OG1 . THR   A 1 199 ? 62.47850 19.87515  28.19120  1.000 91.74436  ? 199 THR   A OG1 1 
ATOM   1472 C  CG2 . THR   A 1 199 ? 63.69555 19.50754  26.14575  1.000 95.77217  ? 199 THR   A CG2 1 
ATOM   1473 N  N   . CYS   A 1 200 ? 61.38428 16.99672  29.36507  1.000 98.51030  ? 200 CYS   A N   1 
ATOM   1474 C  CA  . CYS   A 1 200 ? 60.97435 16.60394  30.71408  1.000 98.06365  ? 200 CYS   A CA  1 
ATOM   1475 C  C   . CYS   A 1 200 ? 61.48421 17.60496  31.75406  1.000 95.90360  ? 200 CYS   A C   1 
ATOM   1476 O  O   . CYS   A 1 200 ? 62.28682 17.28368  32.63309  1.000 99.65633  ? 200 CYS   A O   1 
ATOM   1477 C  CB  . CYS   A 1 200 ? 61.44037 15.17918  31.03627  1.000 99.43124  ? 200 CYS   A CB  1 
ATOM   1478 S  SG  . CYS   A 1 200 ? 60.78958 13.91235  29.92220  1.000 91.25008  ? 200 CYS   A SG  1 
ATOM   1479 N  N   . ALA   A 1 201 ? 60.99593 18.83808  31.63563  1.000 91.25957  ? 201 ALA   A N   1 
ATOM   1480 C  CA  . ALA   A 1 201 ? 61.38292 19.91630  32.53248  1.000 97.25643  ? 201 ALA   A CA  1 
ATOM   1481 C  C   . ALA   A 1 201 ? 60.15205 20.71697  32.92649  1.000 94.88949  ? 201 ALA   A C   1 
ATOM   1482 O  O   . ALA   A 1 201 ? 59.25809 20.94179  32.10539  1.000 90.94142  ? 201 ALA   A O   1 
ATOM   1483 C  CB  . ALA   A 1 201 ? 62.42381 20.83893  31.88608  1.000 106.92141 ? 201 ALA   A CB  1 
ATOM   1484 N  N   . LYS   A 1 202 ? 60.11412 21.14432  34.18642  1.000 89.90148  ? 202 LYS   A N   1 
ATOM   1485 C  CA  . LYS   A 1 202 ? 58.99021 21.92801  34.67941  1.000 93.93191  ? 202 LYS   A CA  1 
ATOM   1486 C  C   . LYS   A 1 202 ? 58.99176 23.30435  34.02856  1.000 98.70959  ? 202 LYS   A C   1 
ATOM   1487 O  O   . LYS   A 1 202 ? 60.00912 24.00349  34.03109  1.000 99.02469  ? 202 LYS   A O   1 
ATOM   1488 C  CB  . LYS   A 1 202 ? 59.05770 22.05742  36.19993  1.000 95.22659  ? 202 LYS   A CB  1 
ATOM   1489 C  CG  . LYS   A 1 202 ? 57.79395 22.61931  36.83025  1.000 94.65331  ? 202 LYS   A CG  1 
ATOM   1490 C  CD  . LYS   A 1 202 ? 58.02888 23.00279  38.28080  1.000 90.61501  ? 202 LYS   A CD  1 
ATOM   1491 C  CE  . LYS   A 1 202 ? 58.52232 21.82193  39.10142  1.000 94.36421  ? 202 LYS   A CE  1 
ATOM   1492 N  NZ  . LYS   A 1 202 ? 58.78975 22.21189  40.51440  1.000 88.71643  ? 202 LYS   A NZ  1 
ATOM   1493 N  N   . LEU   A 1 203 ? 57.84723 23.69364  33.46801  1.000 102.27701 ? 203 LEU   A N   1 
ATOM   1494 C  CA  . LEU   A 1 203 ? 57.73103 24.94798  32.73214  1.000 95.85430  ? 203 LEU   A CA  1 
ATOM   1495 C  C   . LEU   A 1 203 ? 57.07605 26.04833  33.56175  1.000 93.52398  ? 203 LEU   A C   1 
ATOM   1496 O  O   . LEU   A 1 203 ? 57.65935 27.12151  33.73737  1.000 97.23983  ? 203 LEU   A O   1 
ATOM   1497 C  CB  . LEU   A 1 203 ? 56.95290 24.72002  31.43004  1.000 92.05248  ? 203 LEU   A CB  1 
ATOM   1498 C  CG  . LEU   A 1 203 ? 57.56095 23.69681  30.46673  1.000 93.88559  ? 203 LEU   A CG  1 
ATOM   1499 C  CD1 . LEU   A 1 203 ? 56.81591 23.68731  29.14252  1.000 92.53933  ? 203 LEU   A CD1 1 
ATOM   1500 C  CD2 . LEU   A 1 203 ? 59.04464 23.96642  30.24957  1.000 95.16595  ? 203 LEU   A CD2 1 
ATOM   1501 N  N   . MET   A 1 204 ? 55.87491 25.80253  34.08058  1.000 90.73833  ? 204 MET   A N   1 
ATOM   1502 C  CA  . MET   A 1 204 ? 55.17290 26.83432  34.83081  1.000 89.77982  ? 204 MET   A CA  1 
ATOM   1503 C  C   . MET   A 1 204 ? 54.12991 26.19769  35.73889  1.000 92.23519  ? 204 MET   A C   1 
ATOM   1504 O  O   . MET   A 1 204 ? 53.66754 25.07352  35.50823  1.000 93.80578  ? 204 MET   A O   1 
ATOM   1505 C  CB  . MET   A 1 204 ? 54.52132 27.85890  33.89444  1.000 85.78687  ? 204 MET   A CB  1 
ATOM   1506 C  CG  . MET   A 1 204 ? 53.48483 27.27384  32.95755  1.000 82.38823  ? 204 MET   A CG  1 
ATOM   1507 S  SD  . MET   A 1 204 ? 53.03604 28.39063  31.61574  1.000 85.10079  ? 204 MET   A SD  1 
ATOM   1508 C  CE  . MET   A 1 204 ? 54.58578 28.48200  30.72240  1.000 96.56169  ? 204 MET   A CE  1 
ATOM   1509 N  N   . LYS   A 1 205 ? 53.77354 26.94412  36.78369  1.000 94.33519  ? 205 LYS   A N   1 
ATOM   1510 C  CA  . LYS   A 1 205 ? 52.75935 26.56343  37.76510  1.000 92.41898  ? 205 LYS   A CA  1 
ATOM   1511 C  C   . LYS   A 1 205 ? 51.64423 27.60441  37.69537  1.000 94.65860  ? 205 LYS   A C   1 
ATOM   1512 O  O   . LYS   A 1 205 ? 51.66326 28.59804  38.42620  1.000 105.75037 ? 205 LYS   A O   1 
ATOM   1513 C  CB  . LYS   A 1 205 ? 53.35145 26.47697  39.17991  1.000 87.33896  ? 205 LYS   A CB  1 
ATOM   1514 C  CG  . LYS   A 1 205 ? 54.59374 25.61014  39.30919  1.000 94.37300  ? 205 LYS   A CG  1 
ATOM   1515 C  CD  . LYS   A 1 205 ? 55.12330 25.64057  40.73849  1.000 97.83636  ? 205 LYS   A CD  1 
ATOM   1516 C  CE  . LYS   A 1 205 ? 56.38206 24.80102  40.89568  1.000 92.84942  ? 205 LYS   A CE  1 
ATOM   1517 N  NZ  . LYS   A 1 205 ? 56.89287 24.80657  42.29658  1.000 72.46218  ? 205 LYS   A NZ  1 
ATOM   1518 N  N   . LEU   A 1 206 ? 50.67713 27.37702  36.81001  1.000 86.63464  ? 206 LEU   A N   1 
ATOM   1519 C  CA  . LEU   A 1 206 ? 49.54417 28.28324  36.67681  1.000 79.02989  ? 206 LEU   A CA  1 
ATOM   1520 C  C   . LEU   A 1 206 ? 48.65907 28.18224  37.91274  1.000 76.91301  ? 206 LEU   A C   1 
ATOM   1521 O  O   . LEU   A 1 206 ? 48.14535 27.10414  38.23372  1.000 78.50035  ? 206 LEU   A O   1 
ATOM   1522 C  CB  . LEU   A 1 206 ? 48.75635 27.95792  35.41153  1.000 73.09412  ? 206 LEU   A CB  1 
ATOM   1523 C  CG  . LEU   A 1 206 ? 49.58136 27.96957  34.12265  1.000 65.29721  ? 206 LEU   A CG  1 
ATOM   1524 C  CD1 . LEU   A 1 206 ? 48.69882 27.75484  32.90279  1.000 64.02380  ? 206 LEU   A CD1 1 
ATOM   1525 C  CD2 . LEU   A 1 206 ? 50.37454 29.26383  33.99690  1.000 73.21722  ? 206 LEU   A CD2 1 
ATOM   1526 N  N   . LYS   A 1 207 ? 48.47954 29.31013  38.59655  1.000 66.02935  ? 207 LYS   A N   1 
ATOM   1527 C  CA  . LYS   A 1 207 ? 47.85719 29.38369  39.91758  1.000 66.85477  ? 207 LYS   A CA  1 
ATOM   1528 C  C   . LYS   A 1 207 ? 46.59210 30.22942  39.80765  1.000 67.59237  ? 207 LYS   A C   1 
ATOM   1529 O  O   . LYS   A 1 207 ? 46.57801 31.40035  40.19366  1.000 77.09761  ? 207 LYS   A O   1 
ATOM   1530 C  CB  . LYS   A 1 207 ? 48.86071 29.97909  40.91974  1.000 68.44486  ? 207 LYS   A CB  1 
ATOM   1531 C  CG  . LYS   A 1 207 ? 48.46696 29.88744  42.38219  1.000 69.42256  ? 207 LYS   A CG  1 
ATOM   1532 C  CD  . LYS   A 1 207 ? 49.29743 30.85818  43.21477  1.000 75.89498  ? 207 LYS   A CD  1 
ATOM   1533 C  CE  . LYS   A 1 207 ? 50.77562 30.78220  42.85539  1.000 74.16001  ? 207 LYS   A CE  1 
ATOM   1534 N  NZ  . LYS   A 1 207 ? 51.56390 31.86847  43.50291  1.000 67.10810  ? 207 LYS   A NZ  1 
ATOM   1535 N  N   . GLY   A 1 208 ? 45.52614 29.63126  39.27974  1.000 62.61163  ? 208 GLY   A N   1 
ATOM   1536 C  CA  . GLY   A 1 208 ? 44.29843 30.36785  39.04905  1.000 61.08884  ? 208 GLY   A CA  1 
ATOM   1537 C  C   . GLY   A 1 208 ? 43.05859 29.76215  39.67536  1.000 63.28338  ? 208 GLY   A C   1 
ATOM   1538 O  O   . GLY   A 1 208 ? 42.24594 30.47866  40.26753  1.000 57.56937  ? 208 GLY   A O   1 
ATOM   1539 N  N   . HIS   A 1 209 ? 42.89953 28.44656  39.55570  1.000 68.18675  ? 209 HIS   A N   1 
ATOM   1540 C  CA  . HIS   A 1 209 ? 41.68456 27.79555  40.02004  1.000 65.10051  ? 209 HIS   A CA  1 
ATOM   1541 C  C   . HIS   A 1 209 ? 41.62794 27.76183  41.54683  1.000 64.92688  ? 209 HIS   A C   1 
ATOM   1542 O  O   . HIS   A 1 209 ? 42.59772 28.06582  42.24771  1.000 65.18047  ? 209 HIS   A O   1 
ATOM   1543 C  CB  . HIS   A 1 209 ? 41.58641 26.37779  39.45984  1.000 60.30402  ? 209 HIS   A CB  1 
ATOM   1544 C  CG  . HIS   A 1 209 ? 41.16581 26.32393  38.02514  1.000 64.33396  ? 209 HIS   A CG  1 
ATOM   1545 N  ND1 . HIS   A 1 209 ? 39.87724 26.59445  37.61802  1.000 68.66428  ? 209 HIS   A ND1 1 
ATOM   1546 C  CD2 . HIS   A 1 209 ? 41.86131 26.02887  36.90176  1.000 65.67910  ? 209 HIS   A CD2 1 
ATOM   1547 C  CE1 . HIS   A 1 209 ? 39.79609 26.46528  36.30597  1.000 67.19675  ? 209 HIS   A CE1 1 
ATOM   1548 N  NE2 . HIS   A 1 209 ? 40.98704 26.12614  35.84674  1.000 64.55762  ? 209 HIS   A NE2 1 
ATOM   1549 N  N   . THR   A 1 210 ? 40.45513 27.38011  42.05955  1.000 63.08232  ? 210 THR   A N   1 
ATOM   1550 C  CA  . THR   A 1 210 ? 40.23133 27.25683  43.49387  1.000 64.14654  ? 210 THR   A CA  1 
ATOM   1551 C  C   . THR   A 1 210 ? 39.69847 25.88310  43.88393  1.000 63.14868  ? 210 THR   A C   1 
ATOM   1552 O  O   . THR   A 1 210 ? 39.27628 25.70029  45.03203  1.000 60.69302  ? 210 THR   A O   1 
ATOM   1553 C  CB  . THR   A 1 210 ? 39.26564 28.34139  43.98811  1.000 66.21867  ? 210 THR   A CB  1 
ATOM   1554 O  OG1 . THR   A 1 210 ? 39.03768 28.17659  45.39331  1.000 74.37380  ? 210 THR   A OG1 1 
ATOM   1555 C  CG2 . THR   A 1 210 ? 37.93827 28.24810  43.25301  1.000 58.70312  ? 210 THR   A CG2 1 
ATOM   1556 N  N   . ASP   A 1 211 ? 39.70446 24.91872  42.96825  1.000 70.64767  ? 211 ASP   A N   1 
ATOM   1557 C  CA  . ASP   A 1 211 ? 39.20752 23.57892  43.25295  1.000 68.52393  ? 211 ASP   A CA  1 
ATOM   1558 C  C   . ASP   A 1 211 ? 39.87204 22.60775  42.28301  1.000 59.74983  ? 211 ASP   A C   1 
ATOM   1559 O  O   . ASP   A 1 211 ? 40.74874 22.98327  41.49972  1.000 62.20726  ? 211 ASP   A O   1 
ATOM   1560 C  CB  . ASP   A 1 211 ? 37.67885 23.52836  43.15797  1.000 67.13132  ? 211 ASP   A CB  1 
ATOM   1561 C  CG  . ASP   A 1 211 ? 37.08083 22.38443  43.95477  1.000 65.96732  ? 211 ASP   A CG  1 
ATOM   1562 O  OD1 . ASP   A 1 211 ? 37.85489 21.57104  44.50254  1.000 60.23064  ? 211 ASP   A OD1 1 
ATOM   1563 O  OD2 . ASP   A 1 211 ? 35.83721 22.30123  44.03552  1.000 70.03335  ? 211 ASP   A OD2 1 
ATOM   1564 N  N   . ASN   A 1 212 ? 39.44442 21.34918  42.34305  1.000 60.30789  ? 212 ASN   A N   1 
ATOM   1565 C  CA  . ASN   A 1 212 ? 40.03001 20.31091  41.50616  1.000 69.49152  ? 212 ASN   A CA  1 
ATOM   1566 C  C   . ASN   A 1 212 ? 39.64524 20.50927  40.04490  1.000 64.18542  ? 212 ASN   A C   1 
ATOM   1567 O  O   . ASN   A 1 212 ? 38.51003 20.87314  39.72761  1.000 65.10684  ? 212 ASN   A O   1 
ATOM   1568 C  CB  . ASN   A 1 212 ? 39.57779 18.93100  41.98489  1.000 72.69164  ? 212 ASN   A CB  1 
ATOM   1569 C  CG  . ASN   A 1 212 ? 40.16370 17.80406  41.15711  1.000 64.50471  ? 212 ASN   A CG  1 
ATOM   1570 O  OD1 . ASN   A 1 212 ? 41.23523 17.94266  40.56649  1.000 62.96740  ? 212 ASN   A OD1 1 
ATOM   1571 N  ND2 . ASN   A 1 212 ? 39.46203 16.67735  41.11244  1.000 67.62439  ? 212 ASN   A ND2 1 
ATOM   1572 N  N   . VAL   A 1 213 ? 40.60234 20.25964  39.15360  1.000 61.77171  ? 213 VAL   A N   1 
ATOM   1573 C  CA  . VAL   A 1 213 ? 40.40553 20.38248  37.71307  1.000 61.48049  ? 213 VAL   A CA  1 
ATOM   1574 C  C   . VAL   A 1 213 ? 40.25404 18.98533  37.12875  1.000 62.41701  ? 213 VAL   A C   1 
ATOM   1575 O  O   . VAL   A 1 213 ? 41.05845 18.09213  37.42369  1.000 64.38898  ? 213 VAL   A O   1 
ATOM   1576 C  CB  . VAL   A 1 213 ? 41.57755 21.13107  37.05543  1.000 66.01016  ? 213 VAL   A CB  1 
ATOM   1577 C  CG1 . VAL   A 1 213 ? 41.25001 21.47487  35.61146  1.000 66.47684  ? 213 VAL   A CG1 1 
ATOM   1578 C  CG2 . VAL   A 1 213 ? 41.92180 22.38357  37.84960  1.000 70.07113  ? 213 VAL   A CG2 1 
ATOM   1579 N  N   . LYS   A 1 214 ? 39.22777 18.78998  36.29787  1.000 59.50977  ? 214 LYS   A N   1 
ATOM   1580 C  CA  . LYS   A 1 214 ? 38.93027 17.47253  35.75225  1.000 58.08002  ? 214 LYS   A CA  1 
ATOM   1581 C  C   . LYS   A 1 214 ? 38.92731 17.41583  34.23076  1.000 69.21584  ? 214 LYS   A C   1 
ATOM   1582 O  O   . LYS   A 1 214 ? 38.61043 16.35947  33.67107  1.000 75.17538  ? 214 LYS   A O   1 
ATOM   1583 C  CB  . LYS   A 1 214 ? 37.57683 16.97101  36.27676  1.000 49.27417  ? 214 LYS   A CB  1 
ATOM   1584 C  CG  . LYS   A 1 214 ? 37.60831 16.48721  37.71714  1.000 51.09895  ? 214 LYS   A CG  1 
ATOM   1585 C  CD  . LYS   A 1 214 ? 36.27465 15.88188  38.12578  1.000 50.78459  ? 214 LYS   A CD  1 
ATOM   1586 C  CE  . LYS   A 1 214 ? 36.35024 15.26318  39.51285  1.000 48.67784  ? 214 LYS   A CE  1 
ATOM   1587 N  NZ  . LYS   A 1 214 ? 35.04471 14.68507  39.93647  1.000 49.41068  ? 214 LYS   A NZ  1 
ATOM   1588 N  N   . ALA   A 1 215 ? 39.26924 18.50392  33.54448  1.000 64.01894  ? 215 ALA   A N   1 
ATOM   1589 C  CA  . ALA   A 1 215 ? 39.28658 18.49802  32.08870  1.000 60.72881  ? 215 ALA   A CA  1 
ATOM   1590 C  C   . ALA   A 1 215 ? 40.23592 19.58001  31.59677  1.000 61.92536  ? 215 ALA   A C   1 
ATOM   1591 O  O   . ALA   A 1 215 ? 40.21102 20.70729  32.09610  1.000 62.97664  ? 215 ALA   A O   1 
ATOM   1592 C  CB  . ALA   A 1 215 ? 37.88310 18.71511  31.51063  1.000 58.65135  ? 215 ALA   A CB  1 
ATOM   1593 N  N   . LEU   A 1 216 ? 41.06650 19.22721  30.61681  1.000 70.56369  ? 216 LEU   A N   1 
ATOM   1594 C  CA  . LEU   A 1 216 ? 42.03329 20.14980  30.04008  1.000 62.68882  ? 216 LEU   A CA  1 
ATOM   1595 C  C   . LEU   A 1 216 ? 42.00690 20.02150  28.52348  1.000 66.14247  ? 216 LEU   A C   1 
ATOM   1596 O  O   . LEU   A 1 216 ? 41.57681 19.00493  27.97296  1.000 70.89109  ? 216 LEU   A O   1 
ATOM   1597 C  CB  . LEU   A 1 216 ? 43.45199 19.88720  30.56623  1.000 59.70158  ? 216 LEU   A CB  1 
ATOM   1598 C  CG  . LEU   A 1 216 ? 43.66740 19.97700  32.07829  1.000 57.35430  ? 216 LEU   A CG  1 
ATOM   1599 C  CD1 . LEU   A 1 216 ? 45.08556 19.56641  32.44056  1.000 63.44772  ? 216 LEU   A CD1 1 
ATOM   1600 C  CD2 . LEU   A 1 216 ? 43.36944 21.37985  32.58039  1.000 63.02380  ? 216 LEU   A CD2 1 
ATOM   1601 N  N   . LEU   A 1 217 ? 42.47900 21.06975  27.85074  1.000 65.02919  ? 217 LEU   A N   1 
ATOM   1602 C  CA  . LEU   A 1 217 ? 42.53478 21.08526  26.39606  1.000 67.41738  ? 217 LEU   A CA  1 
ATOM   1603 C  C   . LEU   A 1 217 ? 43.63481 22.03189  25.93983  1.000 65.99882  ? 217 LEU   A C   1 
ATOM   1604 O  O   . LEU   A 1 217 ? 44.04545 22.93967  26.66724  1.000 69.80753  ? 217 LEU   A O   1 
ATOM   1605 C  CB  . LEU   A 1 217 ? 41.19212 21.49625  25.77987  1.000 68.07976  ? 217 LEU   A CB  1 
ATOM   1606 C  CG  . LEU   A 1 217 ? 40.28016 20.35890  25.31928  1.000 68.35775  ? 217 LEU   A CG  1 
ATOM   1607 C  CD1 . LEU   A 1 217 ? 38.95878 20.91055  24.82151  1.000 63.62991  ? 217 LEU   A CD1 1 
ATOM   1608 C  CD2 . LEU   A 1 217 ? 40.96146 19.53593  24.23656  1.000 69.66581  ? 217 LEU   A CD2 1 
ATOM   1609 N  N   . LEU   A 1 218 ? 44.10553 21.80502  24.71538  1.000 65.14758  ? 218 LEU   A N   1 
ATOM   1610 C  CA  . LEU   A 1 218 ? 45.14712 22.61903  24.10785  1.000 70.28518  ? 218 LEU   A CA  1 
ATOM   1611 C  C   . LEU   A 1 218 ? 44.85339 22.76963  22.62276  1.000 78.23880  ? 218 LEU   A C   1 
ATOM   1612 O  O   . LEU   A 1 218 ? 44.15876 21.94708  22.02075  1.000 79.96662  ? 218 LEU   A O   1 
ATOM   1613 C  CB  . LEU   A 1 218 ? 46.53947 22.00472  24.31383  1.000 70.25203  ? 218 LEU   A CB  1 
ATOM   1614 C  CG  . LEU   A 1 218 ? 47.13572 22.08957  25.71949  1.000 64.76763  ? 218 LEU   A CG  1 
ATOM   1615 C  CD1 . LEU   A 1 218 ? 48.27965 21.10301  25.88035  1.000 68.98464  ? 218 LEU   A CD1 1 
ATOM   1616 C  CD2 . LEU   A 1 218 ? 47.61058 23.50402  26.00235  1.000 73.39442  ? 218 LEU   A CD2 1 
ATOM   1617 N  N   . ASN   A 1 219 ? 45.39258 23.83360  22.03354  1.000 77.99294  ? 219 ASN   A N   1 
ATOM   1618 C  CA  . ASN   A 1 219 ? 45.21576 24.07999  20.60873  1.000 85.98400  ? 219 ASN   A CA  1 
ATOM   1619 C  C   . ASN   A 1 219 ? 46.22187 23.24130  19.82002  1.000 87.01659  ? 219 ASN   A C   1 
ATOM   1620 O  O   . ASN   A 1 219 ? 46.92529 22.38829  20.36856  1.000 83.02124  ? 219 ASN   A O   1 
ATOM   1621 C  CB  . ASN   A 1 219 ? 45.33818 25.57110  20.30479  1.000 87.18978  ? 219 ASN   A CB  1 
ATOM   1622 C  CG  . ASN   A 1 219 ? 46.71298 26.12098  20.62051  1.000 89.98231  ? 219 ASN   A CG  1 
ATOM   1623 O  OD1 . ASN   A 1 219 ? 47.33691 25.73499  21.60823  1.000 87.98336  ? 219 ASN   A OD1 1 
ATOM   1624 N  ND2 . ASN   A 1 219 ? 47.19385 27.02932  19.77894  1.000 91.92528  ? 219 ASN   A ND2 1 
ATOM   1625 N  N   . ARG   A 1 220 ? 46.30405 23.48265  18.50993  1.000 89.93580  ? 220 ARG   A N   1 
ATOM   1626 C  CA  . ARG   A 1 220 ? 47.13624 22.64263  17.65384  1.000 89.04492  ? 220 ARG   A CA  1 
ATOM   1627 C  C   . ARG   A 1 220 ? 48.62103 22.88944  17.89972  1.000 87.83538  ? 220 ARG   A C   1 
ATOM   1628 O  O   . ARG   A 1 220 ? 49.39657 21.94158  18.07010  1.000 91.14667  ? 220 ARG   A O   1 
ATOM   1629 C  CB  . ARG   A 1 220 ? 46.78347 22.87715  16.18381  1.000 89.52474  ? 220 ARG   A CB  1 
ATOM   1630 C  CG  . ARG   A 1 220 ? 46.65142 24.34055  15.78891  1.000 87.10328  ? 220 ARG   A CG  1 
ATOM   1631 C  CD  . ARG   A 1 220 ? 46.79816 24.52889  14.28554  1.000 92.77645  ? 220 ARG   A CD  1 
ATOM   1632 N  NE  . ARG   A 1 220 ? 48.16690 24.30076  13.83529  1.000 99.36216  ? 220 ARG   A NE  1 
ATOM   1633 C  CZ  . ARG   A 1 220 ? 48.60727 23.16593  13.30838  1.000 102.55371 ? 220 ARG   A CZ  1 
ATOM   1634 N  NH1 . ARG   A 1 220 ? 47.80699 22.12631  13.13704  1.000 97.84826  ? 220 ARG   A NH1 1 
ATOM   1635 N  NH2 . ARG   A 1 220 ? 49.88288 23.07210  12.94351  1.000 101.10553 ? 220 ARG   A NH2 1 
ATOM   1636 N  N   . ASP   A 1 221 ? 49.03730 24.15342  17.92269  1.000 89.82171  ? 221 ASP   A N   1 
ATOM   1637 C  CA  . ASP   A 1 221 ? 50.44429 24.50392  18.05925  1.000 90.53235  ? 221 ASP   A CA  1 
ATOM   1638 C  C   . ASP   A 1 221 ? 50.86257 24.74627  19.50518  1.000 86.40399  ? 221 ASP   A C   1 
ATOM   1639 O  O   . ASP   A 1 221 ? 52.00197 25.15868  19.74518  1.000 86.30155  ? 221 ASP   A O   1 
ATOM   1640 C  CB  . ASP   A 1 221 ? 50.76485 25.73609  17.20774  1.000 88.85452  ? 221 ASP   A CB  1 
ATOM   1641 C  CG  . ASP   A 1 221 ? 49.78369 26.86926  17.42794  1.000 87.98649  ? 221 ASP   A CG  1 
ATOM   1642 O  OD1 . ASP   A 1 221 ? 48.59192 26.58677  17.67215  1.000 93.61539  ? 221 ASP   A OD1 1 
ATOM   1643 O  OD2 . ASP   A 1 221 ? 50.20375 28.04291  17.35374  1.000 85.60697  ? 221 ASP   A OD2 1 
ATOM   1644 N  N   . GLY   A 1 222 ? 49.97663 24.49968  20.46695  1.000 81.60050  ? 222 GLY   A N   1 
ATOM   1645 C  CA  . GLY   A 1 222 ? 50.32420 24.63051  21.86862  1.000 78.51964  ? 222 GLY   A CA  1 
ATOM   1646 C  C   . GLY   A 1 222 ? 50.63539 26.04816  22.30289  1.000 81.74173  ? 222 GLY   A C   1 
ATOM   1647 O  O   . GLY   A 1 222 ? 51.70717 26.31120  22.85644  1.000 79.54043  ? 222 GLY   A O   1 
ATOM   1648 N  N   . THR   A 1 223 ? 49.70647 26.97227  22.05890  1.000 85.64798  ? 223 THR   A N   1 
ATOM   1649 C  CA  . THR   A 1 223 ? 49.86940 28.36407  22.45899  1.000 83.19381  ? 223 THR   A CA  1 
ATOM   1650 C  C   . THR   A 1 223 ? 48.86385 28.82118  23.50324  1.000 78.16568  ? 223 THR   A C   1 
ATOM   1651 O  O   . THR   A 1 223 ? 49.17560 29.72003  24.28693  1.000 76.87823  ? 223 THR   A O   1 
ATOM   1652 C  CB  . THR   A 1 223 ? 49.76943 29.29056  21.23862  1.000 85.07203  ? 223 THR   A CB  1 
ATOM   1653 O  OG1 . THR   A 1 223 ? 48.58217 28.98706  20.49485  1.000 80.99170  ? 223 THR   A OG1 1 
ATOM   1654 C  CG2 . THR   A 1 223 ? 50.98667 29.12490  20.34065  1.000 82.40932  ? 223 THR   A CG2 1 
ATOM   1655 N  N   . GLN   A 1 224 ? 47.67093 28.23102  23.53427  1.000 77.47418  ? 224 GLN   A N   1 
ATOM   1656 C  CA  . GLN   A 1 224 ? 46.65696 28.56698  24.52180  1.000 78.12512  ? 224 GLN   A CA  1 
ATOM   1657 C  C   . GLN   A 1 224 ? 46.13558 27.29252  25.16771  1.000 79.68304  ? 224 GLN   A C   1 
ATOM   1658 O  O   . GLN   A 1 224 ? 46.17972 26.21228  24.57052  1.000 78.42104  ? 224 GLN   A O   1 
ATOM   1659 C  CB  . GLN   A 1 224 ? 45.49383 29.34897  23.89899  1.000 78.43218  ? 224 GLN   A CB  1 
ATOM   1660 C  CG  . GLN   A 1 224 ? 45.91647 30.61139  23.16972  1.000 80.87731  ? 224 GLN   A CG  1 
ATOM   1661 C  CD  . GLN   A 1 224 ? 44.75769 31.55607  22.92696  1.000 85.06469  ? 224 GLN   A CD  1 
ATOM   1662 O  OE1 . GLN   A 1 224 ? 44.33946 31.76673  21.78839  1.000 88.66613  ? 224 GLN   A OE1 1 
ATOM   1663 N  NE2 . GLN   A 1 224 ? 44.23426 32.13593  24.00087  1.000 86.29408  ? 224 GLN   A NE2 1 
ATOM   1664 N  N   . CYS   A 1 225 ? 45.63491 27.42776  26.39605  1.000 80.43302  ? 225 CYS   A N   1 
ATOM   1665 C  CA  . CYS   A 1 225 ? 45.16024 26.28179  27.15949  1.000 72.86374  ? 225 CYS   A CA  1 
ATOM   1666 C  C   . CYS   A 1 225 ? 43.77590 26.55291  27.73056  1.000 70.46386  ? 225 CYS   A C   1 
ATOM   1667 O  O   . CYS   A 1 225 ? 43.45806 27.68287  28.11340  1.000 75.76518  ? 225 CYS   A O   1 
ATOM   1668 C  CB  . CYS   A 1 225 ? 46.12532 25.93056  28.29808  1.000 67.08848  ? 225 CYS   A CB  1 
ATOM   1669 S  SG  . CYS   A 1 225 ? 45.60030 24.52932  29.31674  1.000 60.98863  ? 225 CYS   A SG  1 
ATOM   1670 N  N   . LEU   A 1 226 ? 42.96055 25.50265  27.78615  1.000 62.24589  ? 226 LEU   A N   1 
ATOM   1671 C  CA  . LEU   A 1 226 ? 41.63822 25.53811  28.39330  1.000 57.51855  ? 226 LEU   A CA  1 
ATOM   1672 C  C   . LEU   A 1 226 ? 41.62392 24.63876  29.62020  1.000 64.63356  ? 226 LEU   A C   1 
ATOM   1673 O  O   . LEU   A 1 226 ? 42.24808 23.57291  29.62587  1.000 71.33320  ? 226 LEU   A O   1 
ATOM   1674 C  CB  . LEU   A 1 226 ? 40.56127 25.08467  27.40402  1.000 58.98648  ? 226 LEU   A CB  1 
ATOM   1675 C  CG  . LEU   A 1 226 ? 40.21662 26.06135  26.28035  1.000 60.88614  ? 226 LEU   A CG  1 
ATOM   1676 C  CD1 . LEU   A 1 226 ? 39.28092 25.41566  25.27088  1.000 71.61292  ? 226 LEU   A CD1 1 
ATOM   1677 C  CD2 . LEU   A 1 226 ? 39.59571 27.32348  26.85460  1.000 56.61022  ? 226 LEU   A CD2 1 
ATOM   1678 N  N   . SER   A 1 227 ? 40.90761 25.06955  30.65590  1.000 66.70423  ? 227 SER   A N   1 
ATOM   1679 C  CA  . SER   A 1 227 ? 40.87133 24.34215  31.91553  1.000 67.86377  ? 227 SER   A CA  1 
ATOM   1680 C  C   . SER   A 1 227 ? 39.45308 24.32090  32.46304  1.000 63.53078  ? 227 SER   A C   1 
ATOM   1681 O  O   . SER   A 1 227 ? 38.75598 25.33895  32.43959  1.000 71.30661  ? 227 SER   A O   1 
ATOM   1682 C  CB  . SER   A 1 227 ? 41.81336 24.97419  32.94490  1.000 68.40384  ? 227 SER   A CB  1 
ATOM   1683 O  OG  . SER   A 1 227 ? 43.00508 25.42670  32.32865  1.000 71.94107  ? 227 SER   A OG  1 
ATOM   1684 N  N   . GLY   A 1 228 ? 39.04004 23.15875  32.96520  1.000 62.17877  ? 228 GLY   A N   1 
ATOM   1685 C  CA  . GLY   A 1 228 ? 37.72898 22.99994  33.56353  1.000 63.16141  ? 228 GLY   A CA  1 
ATOM   1686 C  C   . GLY   A 1 228 ? 37.79593 22.38907  34.94783  1.000 67.69732  ? 228 GLY   A C   1 
ATOM   1687 O  O   . GLY   A 1 228 ? 38.08402 21.19639  35.09787  1.000 69.42736  ? 228 GLY   A O   1 
ATOM   1688 N  N   . SER   A 1 229 ? 37.52812 23.19620  35.96752  1.000 69.27047  ? 229 SER   A N   1 
ATOM   1689 C  CA  . SER   A 1 229 ? 37.63789 22.76387  37.35112  1.000 68.17602  ? 229 SER   A CA  1 
ATOM   1690 C  C   . SER   A 1 229 ? 36.26053 22.52385  37.96041  1.000 61.90858  ? 229 SER   A C   1 
ATOM   1691 O  O   . SER   A 1 229 ? 35.22160 22.82862  37.37015  1.000 59.40732  ? 229 SER   A O   1 
ATOM   1692 C  CB  . SER   A 1 229 ? 38.41264 23.79541  38.17566  1.000 65.81920  ? 229 SER   A CB  1 
ATOM   1693 O  OG  . SER   A 1 229 ? 38.45026 23.43191  39.54466  1.000 68.26850  ? 229 SER   A OG  1 
ATOM   1694 N  N   . SER   A 1 230 ? 36.27013 21.96653  39.17164  1.000 60.68185  ? 230 SER   A N   1 
ATOM   1695 C  CA  . SER   A 1 230 ? 35.05788 21.65487  39.91638  1.000 59.59787  ? 230 SER   A CA  1 
ATOM   1696 C  C   . SER   A 1 230 ? 34.48400 22.85988  40.65012  1.000 59.66156  ? 230 SER   A C   1 
ATOM   1697 O  O   . SER   A 1 230 ? 33.64241 22.68749  41.54034  1.000 59.06278  ? 230 SER   A O   1 
ATOM   1698 C  CB  . SER   A 1 230 ? 35.33058 20.52301  40.90893  1.000 61.25108  ? 230 SER   A CB  1 
ATOM   1699 O  OG  . SER   A 1 230 ? 35.72105 19.33882  40.23512  1.000 55.40862  ? 230 SER   A OG  1 
ATOM   1700 N  N   . ASP   A 1 231 ? 34.92188 24.06754  40.30572  1.000 59.44132  ? 231 ASP   A N   1 
ATOM   1701 C  CA  . ASP   A 1 231 ? 34.39931 25.29067  40.89503  1.000 63.90965  ? 231 ASP   A CA  1 
ATOM   1702 C  C   . ASP   A 1 231 ? 33.39438 25.99386  39.99350  1.000 67.30211  ? 231 ASP   A C   1 
ATOM   1703 O  O   . ASP   A 1 231 ? 32.92205 27.08045  40.34226  1.000 69.81568  ? 231 ASP   A O   1 
ATOM   1704 C  CB  . ASP   A 1 231 ? 35.55169 26.24331  41.23257  1.000 64.97276  ? 231 ASP   A CB  1 
ATOM   1705 C  CG  . ASP   A 1 231 ? 36.48451 26.47056  40.05684  1.000 61.86496  ? 231 ASP   A CG  1 
ATOM   1706 O  OD1 . ASP   A 1 231 ? 36.20736 25.93814  38.96151  1.000 59.31890  ? 231 ASP   A OD1 1 
ATOM   1707 O  OD2 . ASP   A 1 231 ? 37.49677 27.18197  40.22645  1.000 57.20656  ? 231 ASP   A OD2 1 
ATOM   1708 N  N   . GLY   A 1 232 ? 33.05404 25.40031  38.85139  1.000 67.68088  ? 232 GLY   A N   1 
ATOM   1709 C  CA  . GLY   A 1 232 ? 32.17142 26.03474  37.89643  1.000 66.03977  ? 232 GLY   A CA  1 
ATOM   1710 C  C   . GLY   A 1 232 ? 32.83844 27.03683  36.98566  1.000 62.01479  ? 232 GLY   A C   1 
ATOM   1711 O  O   . GLY   A 1 232 ? 32.14211 27.72217  36.22800  1.000 63.84682  ? 232 GLY   A O   1 
ATOM   1712 N  N   . THR   A 1 233 ? 34.16302 27.14048  37.02790  1.000 60.86521  ? 233 THR   A N   1 
ATOM   1713 C  CA  . THR   A 1 233 ? 34.90635 28.13502  36.26706  1.000 61.26303  ? 233 THR   A CA  1 
ATOM   1714 C  C   . THR   A 1 233 ? 35.65888 27.44529  35.13861  1.000 59.07493  ? 233 THR   A C   1 
ATOM   1715 O  O   . THR   A 1 233 ? 36.47264 26.54920  35.38785  1.000 57.48121  ? 233 THR   A O   1 
ATOM   1716 C  CB  . THR   A 1 233 ? 35.88668 28.89245  37.16394  1.000 61.63971  ? 233 THR   A CB  1 
ATOM   1717 O  OG1 . THR   A 1 233 ? 37.01422 28.05622  37.45371  1.000 62.08173  ? 233 THR   A OG1 1 
ATOM   1718 C  CG2 . THR   A 1 233 ? 35.21829 29.28880  38.47000  1.000 66.54429  ? 233 THR   A CG2 1 
ATOM   1719 N  N   . ILE   A 1 234 ? 35.38380 27.85559  33.90960  1.000 61.72851  ? 234 ILE   A N   1 
ATOM   1720 C  CA  . ILE   A 1 234 ? 36.22569 27.50342  32.77292  1.000 61.49592  ? 234 ILE   A CA  1 
ATOM   1721 C  C   . ILE   A 1 234 ? 37.27101 28.59634  32.63091  1.000 65.45550  ? 234 ILE   A C   1 
ATOM   1722 O  O   . ILE   A 1 234 ? 36.97608 29.77199  32.85357  1.000 73.57776  ? 234 ILE   A O   1 
ATOM   1723 C  CB  . ILE   A 1 234 ? 35.38972 27.35434  31.48931  1.000 55.69682  ? 234 ILE   A CB  1 
ATOM   1724 C  CG1 . ILE   A 1 234 ? 34.18200 26.45395  31.74418  1.000 59.18169  ? 234 ILE   A CG1 1 
ATOM   1725 C  CG2 . ILE   A 1 234 ? 36.24001 26.79369  30.36078  1.000 56.45465  ? 234 ILE   A CG2 1 
ATOM   1726 C  CD1 . ILE   A 1 234 ? 33.22607 26.38984  30.58360  1.000 59.97112  ? 234 ILE   A CD1 1 
ATOM   1727 N  N   . ARG   A 1 235 ? 38.49837 28.23103  32.28156  1.000 60.78969  ? 235 ARG   A N   1 
ATOM   1728 C  CA  . ARG   A 1 235 ? 39.56132 29.22437  32.22338  1.000 60.53015  ? 235 ARG   A CA  1 
ATOM   1729 C  C   . ARG   A 1 235 ? 40.38161 29.07393  30.95199  1.000 60.12811  ? 235 ARG   A C   1 
ATOM   1730 O  O   . ARG   A 1 235 ? 40.75765 27.96402  30.56687  1.000 67.84392  ? 235 ARG   A O   1 
ATOM   1731 C  CB  . ARG   A 1 235 ? 40.46946 29.13668  33.45701  1.000 67.51187  ? 235 ARG   A CB  1 
ATOM   1732 C  CG  . ARG   A 1 235 ? 39.77706 29.56165  34.74653  1.000 69.09378  ? 235 ARG   A CG  1 
ATOM   1733 C  CD  . ARG   A 1 235 ? 40.75155 29.69196  35.90487  1.000 78.15050  ? 235 ARG   A CD  1 
ATOM   1734 N  NE  . ARG   A 1 235 ? 40.05681 29.82767  37.18001  1.000 83.24110  ? 235 ARG   A NE  1 
ATOM   1735 C  CZ  . ARG   A 1 235 ? 39.76820 30.98438  37.76095  1.000 79.14812  ? 235 ARG   A CZ  1 
ATOM   1736 N  NH1 . ARG   A 1 235 ? 40.11186 32.13857  37.21301  1.000 74.78661  ? 235 ARG   A NH1 1 
ATOM   1737 N  NH2 . ARG   A 1 235 ? 39.11995 30.98278  38.92242  1.000 78.03736  ? 235 ARG   A NH2 1 
ATOM   1738 N  N   . LEU   A 1 236 ? 40.64981 30.20449  30.30603  1.000 57.19425  ? 236 LEU   A N   1 
ATOM   1739 C  CA  . LEU   A 1 236 ? 41.49472 30.27571  29.12092  1.000 64.93611  ? 236 LEU   A CA  1 
ATOM   1740 C  C   . LEU   A 1 236 ? 42.79323 30.97217  29.50059  1.000 72.37590  ? 236 LEU   A C   1 
ATOM   1741 O  O   . LEU   A 1 236 ? 42.76866 32.10686  29.99843  1.000 80.19213  ? 236 LEU   A O   1 
ATOM   1742 C  CB  . LEU   A 1 236 ? 40.79450 31.01717  27.98167  1.000 69.00627  ? 236 LEU   A CB  1 
ATOM   1743 C  CG  . LEU   A 1 236 ? 41.61578 31.22904  26.70689  1.000 72.78064  ? 236 LEU   A CG  1 
ATOM   1744 C  CD1 . LEU   A 1 236 ? 42.14721 29.91081  26.16030  1.000 69.43761  ? 236 LEU   A CD1 1 
ATOM   1745 C  CD2 . LEU   A 1 236 ? 40.78744 31.94637  25.65407  1.000 76.18480  ? 236 LEU   A CD2 1 
ATOM   1746 N  N   . TRP   A 1 237 ? 43.91367 30.29048  29.25814  1.000 68.21756  ? 237 TRP   A N   1 
ATOM   1747 C  CA  . TRP   A 1 237 ? 45.23891 30.71793  29.68061  1.000 73.71732  ? 237 TRP   A CA  1 
ATOM   1748 C  C   . TRP   A 1 237 ? 46.13737 30.90903  28.46763  1.000 80.44984  ? 237 TRP   A C   1 
ATOM   1749 O  O   . TRP   A 1 237 ? 46.10314 30.10689  27.52683  1.000 78.03347  ? 237 TRP   A O   1 
ATOM   1750 C  CB  . TRP   A 1 237 ? 45.89453 29.68749  30.60599  1.000 64.86401  ? 237 TRP   A CB  1 
ATOM   1751 C  CG  . TRP   A 1 237 ? 45.00096 29.07080  31.62231  1.000 68.70190  ? 237 TRP   A CG  1 
ATOM   1752 C  CD1 . TRP   A 1 237 ? 43.95490 28.22467  31.39564  1.000 72.56659  ? 237 TRP   A CD1 1 
ATOM   1753 C  CD2 . TRP   A 1 237 ? 45.10543 29.21032  33.04002  1.000 74.44667  ? 237 TRP   A CD2 1 
ATOM   1754 N  NE1 . TRP   A 1 237 ? 43.38639 27.84807  32.58691  1.000 75.98255  ? 237 TRP   A NE1 1 
ATOM   1755 C  CE2 . TRP   A 1 237 ? 44.07655 28.43890  33.61269  1.000 77.86376  ? 237 TRP   A CE2 1 
ATOM   1756 C  CE3 . TRP   A 1 237 ? 45.96565 29.92066  33.88172  1.000 73.43108  ? 237 TRP   A CE3 1 
ATOM   1757 C  CZ2 . TRP   A 1 237 ? 43.88372 28.35925  34.98911  1.000 76.23408  ? 237 TRP   A CZ2 1 
ATOM   1758 C  CZ3 . TRP   A 1 237 ? 45.77177 29.84384  35.24597  1.000 68.93163  ? 237 TRP   A CZ3 1 
ATOM   1759 C  CH2 . TRP   A 1 237 ? 44.73999 29.06794  35.78736  1.000 72.25570  ? 237 TRP   A CH2 1 
ATOM   1760 N  N   . SER   A 1 238 ? 46.95803 31.95733  28.50594  1.000 83.95253  ? 238 SER   A N   1 
ATOM   1761 C  CA  . SER   A 1 238 ? 47.99538 32.17201  27.50360  1.000 83.40512  ? 238 SER   A CA  1 
ATOM   1762 C  C   . SER   A 1 238 ? 49.30115 31.57380  28.01750  1.000 82.56948  ? 238 SER   A C   1 
ATOM   1763 O  O   . SER   A 1 238 ? 49.75855 31.92074  29.11207  1.000 80.90887  ? 238 SER   A O   1 
ATOM   1764 C  CB  . SER   A 1 238 ? 48.15814 33.66161  27.19813  1.000 85.03636  ? 238 SER   A CB  1 
ATOM   1765 O  OG  . SER   A 1 238 ? 49.16324 33.89022  26.22287  1.000 83.47161  ? 238 SER   A OG  1 
ATOM   1766 N  N   . LEU   A 1 239 ? 49.90337 30.68301  27.22471  1.000 80.71899  ? 239 LEU   A N   1 
ATOM   1767 C  CA  . LEU   A 1 239 ? 51.06799 29.93640  27.69675  1.000 83.61539  ? 239 LEU   A CA  1 
ATOM   1768 C  C   . LEU   A 1 239 ? 52.29385 30.83299  27.82779  1.000 89.55296  ? 239 LEU   A C   1 
ATOM   1769 O  O   . LEU   A 1 239 ? 52.99461 30.79564  28.84616  1.000 88.38917  ? 239 LEU   A O   1 
ATOM   1770 C  CB  . LEU   A 1 239 ? 51.36053 28.76182  26.76046  1.000 84.50000  ? 239 LEU   A CB  1 
ATOM   1771 C  CG  . LEU   A 1 239 ? 50.67062 27.42747  27.06464  1.000 84.29353  ? 239 LEU   A CG  1 
ATOM   1772 C  CD1 . LEU   A 1 239 ? 49.15443 27.55924  27.04171  1.000 82.47374  ? 239 LEU   A CD1 1 
ATOM   1773 C  CD2 . LEU   A 1 239 ? 51.12944 26.35182  26.09084  1.000 76.45630  ? 239 LEU   A CD2 1 
ATOM   1774 N  N   . GLY   A 1 240 ? 52.57621 31.63887  26.80167  1.000 90.44396  ? 240 GLY   A N   1 
ATOM   1775 C  CA  . GLY   A 1 240 ? 53.75835 32.48283  26.83689  1.000 92.54485  ? 240 GLY   A CA  1 
ATOM   1776 C  C   . GLY   A 1 240 ? 53.70721 33.55506  27.90628  1.000 101.05728 ? 240 GLY   A C   1 
ATOM   1777 O  O   . GLY   A 1 240 ? 54.75152 34.00698  28.38548  1.000 112.84603 ? 240 GLY   A O   1 
ATOM   1778 N  N   . GLN   A 1 241 ? 52.50550 33.97353  28.29930  1.000 96.38459  ? 241 GLN   A N   1 
ATOM   1779 C  CA  . GLN   A 1 241 ? 52.34447 35.02506  29.29366  1.000 92.13359  ? 241 GLN   A CA  1 
ATOM   1780 C  C   . GLN   A 1 241 ? 52.22086 34.49272  30.71584  1.000 94.18425  ? 241 GLN   A C   1 
ATOM   1781 O  O   . GLN   A 1 241 ? 52.30434 35.28402  31.66190  1.000 99.83591  ? 241 GLN   A O   1 
ATOM   1782 C  CB  . GLN   A 1 241 ? 51.11911 35.88176  28.95545  1.000 87.36042  ? 241 GLN   A CB  1 
ATOM   1783 C  CG  . GLN   A 1 241 ? 51.13715 36.44019  27.53895  1.000 91.28881  ? 241 GLN   A CG  1 
ATOM   1784 C  CD  . GLN   A 1 241 ? 49.96678 37.36068  27.25377  1.000 91.79651  ? 241 GLN   A CD  1 
ATOM   1785 O  OE1 . GLN   A 1 241 ? 49.35800 37.91214  28.17027  1.000 96.55316  ? 241 GLN   A OE1 1 
ATOM   1786 N  NE2 . GLN   A 1 241 ? 49.64472 37.53002  25.97605  1.000 86.03366  ? 241 GLN   A NE2 1 
ATOM   1787 N  N   . GLN   A 1 242 ? 52.03104 33.18149  30.88469  1.000 93.55537  ? 242 GLN   A N   1 
ATOM   1788 C  CA  . GLN   A 1 242 ? 51.91733 32.54871  32.20137  1.000 90.46547  ? 242 GLN   A CA  1 
ATOM   1789 C  C   . GLN   A 1 242 ? 50.81453 33.19495  33.03923  1.000 85.10881  ? 242 GLN   A C   1 
ATOM   1790 O  O   . GLN   A 1 242 ? 51.00783 33.53185  34.20908  1.000 79.11544  ? 242 GLN   A O   1 
ATOM   1791 C  CB  . GLN   A 1 242 ? 53.25299 32.57842  32.94965  1.000 89.66195  ? 242 GLN   A CB  1 
ATOM   1792 C  CG  . GLN   A 1 242 ? 54.36495 31.78886  32.28891  1.000 88.93846  ? 242 GLN   A CG  1 
ATOM   1793 C  CD  . GLN   A 1 242 ? 55.53940 31.56131  33.21932  1.000 98.78280  ? 242 GLN   A CD  1 
ATOM   1794 O  OE1 . GLN   A 1 242 ? 55.36063 31.28097  34.40506  1.000 94.97884  ? 242 GLN   A OE1 1 
ATOM   1795 N  NE2 . GLN   A 1 242 ? 56.74948 31.68759  32.68795  1.000 104.31675 ? 242 GLN   A NE2 1 
ATOM   1796 N  N   . ARG   A 1 243 ? 49.64298 33.36505  32.43228  1.000 86.17169  ? 243 ARG   A N   1 
ATOM   1797 C  CA  . ARG   A 1 243 ? 48.53138 33.97706  33.14471  1.000 87.52879  ? 243 ARG   A CA  1 
ATOM   1798 C  C   . ARG   A 1 243 ? 47.21896 33.51863  32.52843  1.000 78.71010  ? 243 ARG   A C   1 
ATOM   1799 O  O   . ARG   A 1 243 ? 47.15702 33.18017  31.34302  1.000 71.99268  ? 243 ARG   A O   1 
ATOM   1800 C  CB  . ARG   A 1 243 ? 48.62411 35.50730  33.11989  1.000 91.02620  ? 243 ARG   A CB  1 
ATOM   1801 C  CG  . ARG   A 1 243 ? 48.42632 36.12363  31.74465  1.000 91.23933  ? 243 ARG   A CG  1 
ATOM   1802 C  CD  . ARG   A 1 243 ? 48.50153 37.63942  31.80899  1.000 94.07076  ? 243 ARG   A CD  1 
ATOM   1803 N  NE  . ARG   A 1 243 ? 48.08187 38.25821  30.55770  1.000 98.44545  ? 243 ARG   A NE  1 
ATOM   1804 C  CZ  . ARG   A 1 243 ? 46.83317 38.60559  30.27766  1.000 98.52557  ? 243 ARG   A CZ  1 
ATOM   1805 N  NH1 . ARG   A 1 243 ? 45.85100 38.41102  31.14266  1.000 96.00463  ? 243 ARG   A NH1 1 
ATOM   1806 N  NH2 . ARG   A 1 243 ? 46.56296 39.16256  29.10052  1.000 96.15829  ? 243 ARG   A NH2 1 
ATOM   1807 N  N   . CYS   A 1 244 ? 46.17300 33.51440  33.35211  1.000 75.59850  ? 244 CYS   A N   1 
ATOM   1808 C  CA  . CYS   A 1 244 ? 44.82577 33.21252  32.88652  1.000 71.29162  ? 244 CYS   A CA  1 
ATOM   1809 C  C   . CYS   A 1 244 ? 44.21425 34.46089  32.26548  1.000 69.74644  ? 244 CYS   A C   1 
ATOM   1810 O  O   . CYS   A 1 244 ? 44.04109 35.47496  32.94996  1.000 77.23503  ? 244 CYS   A O   1 
ATOM   1811 C  CB  . CYS   A 1 244 ? 43.96322 32.71507  34.04296  1.000 71.59549  ? 244 CYS   A CB  1 
ATOM   1812 S  SG  . CYS   A 1 244 ? 42.24144 32.41775  33.60458  1.000 81.82608  ? 244 CYS   A SG  1 
ATOM   1813 N  N   . ILE   A 1 245 ? 43.87765 34.38907  30.97841  1.000 67.51864  ? 245 ILE   A N   1 
ATOM   1814 C  CA  . ILE   A 1 245 ? 43.31111 35.55317  30.30736  1.000 73.16867  ? 245 ILE   A CA  1 
ATOM   1815 C  C   . ILE   A 1 245 ? 41.79380 35.64025  30.46795  1.000 73.75534  ? 245 ILE   A C   1 
ATOM   1816 O  O   . ILE   A 1 245 ? 41.23587 36.74160  30.41155  1.000 73.45682  ? 245 ILE   A O   1 
ATOM   1817 C  CB  . ILE   A 1 245 ? 43.69628 35.57995  28.81729  1.000 72.77228  ? 245 ILE   A CB  1 
ATOM   1818 C  CG1 . ILE   A 1 245 ? 42.84764 34.59568  28.01255  1.000 64.34957  ? 245 ILE   A CG1 1 
ATOM   1819 C  CG2 . ILE   A 1 245 ? 45.18468 35.30257  28.63736  1.000 80.17139  ? 245 ILE   A CG2 1 
ATOM   1820 C  CD1 . ILE   A 1 245 ? 43.00753 34.73871  26.51301  1.000 59.04392  ? 245 ILE   A CD1 1 
ATOM   1821 N  N   . ALA   A 1 246 ? 41.10021 34.51715  30.66357  1.000 72.26451  ? 246 ALA   A N   1 
ATOM   1822 C  CA  . ALA   A 1 246 ? 39.64731 34.60022  30.77669  1.000 72.75369  ? 246 ALA   A CA  1 
ATOM   1823 C  C   . ALA   A 1 246 ? 39.11077 33.54451  31.73098  1.000 70.52975  ? 246 ALA   A C   1 
ATOM   1824 O  O   . ALA   A 1 246 ? 39.63462 32.43242  31.79000  1.000 77.78696  ? 246 ALA   A O   1 
ATOM   1825 C  CB  . ALA   A 1 246 ? 38.97421 34.45200  29.40702  1.000 78.99569  ? 246 ALA   A CB  1 
ATOM   1826 N  N   . THR   A 1 247 ? 38.04517 33.89578  32.45276  1.000 65.20863  ? 247 THR   A N   1 
ATOM   1827 C  CA  . THR   A 1 247 ? 37.36539 32.98591  33.37180  1.000 65.89416  ? 247 THR   A CA  1 
ATOM   1828 C  C   . THR   A 1 247 ? 35.86474 33.08681  33.13200  1.000 63.46519  ? 247 THR   A C   1 
ATOM   1829 O  O   . THR   A 1 247 ? 35.24446 34.10114  33.46797  1.000 67.47432  ? 247 THR   A O   1 
ATOM   1830 C  CB  . THR   A 1 247 ? 37.69863 33.30732  34.82726  1.000 71.23797  ? 247 THR   A CB  1 
ATOM   1831 O  OG1 . THR   A 1 247 ? 39.11569 33.23251  35.02593  1.000 78.06312  ? 247 THR   A OG1 1 
ATOM   1832 C  CG2 . THR   A 1 247 ? 37.01043 32.31471  35.74885  1.000 69.75014  ? 247 THR   A CG2 1 
ATOM   1833 N  N   . TYR   A 1 248 ? 35.29274 32.03769  32.55088  1.000 65.00266  ? 248 TYR   A N   1 
ATOM   1834 C  CA  . TYR   A 1 248 ? 33.87905 31.96887  32.21508  1.000 66.92857  ? 248 TYR   A CA  1 
ATOM   1835 C  C   . TYR   A 1 248 ? 33.11603 31.19970  33.28670  1.000 70.37527  ? 248 TYR   A C   1 
ATOM   1836 O  O   . TYR   A 1 248 ? 33.58997 30.17487  33.79057  1.000 64.43940  ? 248 TYR   A O   1 
ATOM   1837 C  CB  . TYR   A 1 248 ? 33.68164 31.29471  30.85587  1.000 62.24225  ? 248 TYR   A CB  1 
ATOM   1838 C  CG  . TYR   A 1 248 ? 34.65983 31.74939  29.79437  1.000 61.85164  ? 248 TYR   A CG  1 
ATOM   1839 C  CD1 . TYR   A 1 248 ? 35.88657 31.11525  29.63396  1.000 63.34361  ? 248 TYR   A CD1 1 
ATOM   1840 C  CD2 . TYR   A 1 248 ? 34.35547 32.80839  28.94950  1.000 67.24707  ? 248 TYR   A CD2 1 
ATOM   1841 C  CE1 . TYR   A 1 248 ? 36.78293 31.52691  28.66707  1.000 61.09711  ? 248 TYR   A CE1 1 
ATOM   1842 C  CE2 . TYR   A 1 248 ? 35.24577 33.22563  27.97742  1.000 62.86959  ? 248 TYR   A CE2 1 
ATOM   1843 C  CZ  . TYR   A 1 248 ? 36.45684 32.58097  27.84060  1.000 58.14918  ? 248 TYR   A CZ  1 
ATOM   1844 O  OH  . TYR   A 1 248 ? 37.34610 32.99278  26.87490  1.000 63.76083  ? 248 TYR   A OH  1 
ATOM   1845 N  N   . ARG   A 1 249 ? 31.92304 31.69419  33.61470  1.000 79.28150  ? 249 ARG   A N   1 
ATOM   1846 C  CA  . ARG   A 1 249 ? 31.04934 31.12432  34.64138  1.000 78.88965  ? 249 ARG   A CA  1 
ATOM   1847 C  C   . ARG   A 1 249 ? 29.72006 30.76283  33.98394  1.000 74.12683  ? 249 ARG   A C   1 
ATOM   1848 O  O   . ARG   A 1 249 ? 28.75965 31.53482  34.02990  1.000 76.71243  ? 249 ARG   A O   1 
ATOM   1849 C  CB  . ARG   A 1 249 ? 30.85154 32.11777  35.79656  1.000 81.76490  ? 249 ARG   A CB  1 
ATOM   1850 C  CG  . ARG   A 1 249 ? 32.13659 32.70566  36.35092  1.000 72.92563  ? 249 ARG   A CG  1 
ATOM   1851 C  CD  . ARG   A 1 249 ? 32.90712 31.67747  37.15329  1.000 79.60554  ? 249 ARG   A CD  1 
ATOM   1852 N  NE  . ARG   A 1 249 ? 32.09424 31.10099  38.21774  1.000 74.74704  ? 249 ARG   A NE  1 
ATOM   1853 C  CZ  . ARG   A 1 249 ? 31.94291 31.63879  39.42023  1.000 73.99484  ? 249 ARG   A CZ  1 
ATOM   1854 N  NH1 . ARG   A 1 249 ? 32.53653 32.77454  39.74915  1.000 78.95333  ? 249 ARG   A NH1 1 
ATOM   1855 N  NH2 . ARG   A 1 249 ? 31.17524 31.02247  40.31461  1.000 68.59340  ? 249 ARG   A NH2 1 
ATOM   1856 N  N   . VAL   A 1 250 ? 29.66327 29.57886  33.37623  1.000 64.03840  ? 250 VAL   A N   1 
ATOM   1857 C  CA  . VAL   A 1 250 ? 28.47038 29.13943  32.65826  1.000 66.47737  ? 250 VAL   A CA  1 
ATOM   1858 C  C   . VAL   A 1 250 ? 27.76092 27.97642  33.33286  1.000 67.53486  ? 250 VAL   A C   1 
ATOM   1859 O  O   . VAL   A 1 250 ? 26.66597 27.59926  32.88336  1.000 73.71822  ? 250 VAL   A O   1 
ATOM   1860 C  CB  . VAL   A 1 250 ? 28.79387 28.77485  31.19353  1.000 65.62641  ? 250 VAL   A CB  1 
ATOM   1861 C  CG1 . VAL   A 1 250 ? 29.33134 29.98789  30.44917  1.000 71.12873  ? 250 VAL   A CG1 1 
ATOM   1862 C  CG2 . VAL   A 1 250 ? 29.78577 27.62682  31.13938  1.000 64.99805  ? 250 VAL   A CG2 1 
ATOM   1863 N  N   . HIS   A 1 251 ? 28.32957 27.40015  34.38817  1.000 68.89085  ? 251 HIS   A N   1 
ATOM   1864 C  CA  . HIS   A 1 251 ? 27.74140 26.25187  35.05979  1.000 67.89978  ? 251 HIS   A CA  1 
ATOM   1865 C  C   . HIS   A 1 251 ? 27.41109 26.59035  36.50728  1.000 71.93144  ? 251 HIS   A C   1 
ATOM   1866 O  O   . HIS   A 1 251 ? 28.07128 27.42260  37.13680  1.000 76.40708  ? 251 HIS   A O   1 
ATOM   1867 C  CB  . HIS   A 1 251 ? 28.68119 25.03990  35.01382  1.000 67.60799  ? 251 HIS   A CB  1 
ATOM   1868 C  CG  . HIS   A 1 251 ? 28.86325 24.46900  33.64218  1.000 64.24728  ? 251 HIS   A CG  1 
ATOM   1869 N  ND1 . HIS   A 1 251 ? 27.91213 23.67892  33.03329  1.000 63.84195  ? 251 HIS   A ND1 1 
ATOM   1870 C  CD2 . HIS   A 1 251 ? 29.88633 24.57210  32.76134  1.000 60.92201  ? 251 HIS   A CD2 1 
ATOM   1871 C  CE1 . HIS   A 1 251 ? 28.34063 23.32127  31.83598  1.000 64.76626  ? 251 HIS   A CE1 1 
ATOM   1872 N  NE2 . HIS   A 1 251 ? 29.53599 23.85002  31.64650  1.000 58.68026  ? 251 HIS   A NE2 1 
ATOM   1873 N  N   . ASP   A 1 252 ? 26.37380 25.93173  37.02934  1.000 74.37149  ? 252 ASP   A N   1 
ATOM   1874 C  CA  . ASP   A 1 252 ? 26.02077 26.08909  38.43629  1.000 77.36700  ? 252 ASP   A CA  1 
ATOM   1875 C  C   . ASP   A 1 252 ? 26.95413 25.29046  39.33868  1.000 72.92757  ? 252 ASP   A C   1 
ATOM   1876 O  O   . ASP   A 1 252 ? 27.40664 25.79583  40.37179  1.000 77.81396  ? 252 ASP   A O   1 
ATOM   1877 C  CB  . ASP   A 1 252 ? 24.56897 25.66269  38.67154  1.000 78.82296  ? 252 ASP   A CB  1 
ATOM   1878 C  CG  . ASP   A 1 252 ? 23.57292 26.53612  37.93203  1.000 93.31686  ? 252 ASP   A CG  1 
ATOM   1879 O  OD1 . ASP   A 1 252 ? 23.52184 26.46052  36.68723  1.000 88.54070  ? 252 ASP   A OD1 1 
ATOM   1880 O  OD2 . ASP   A 1 252 ? 22.83572 27.29729  38.59441  1.000 111.01216 ? 252 ASP   A OD2 1 
ATOM   1881 N  N   . GLU   A 1 253 ? 27.24714 24.04492  38.97233  1.000 62.53830  ? 253 GLU   A N   1 
ATOM   1882 C  CA  . GLU   A 1 253 ? 28.11435 23.18505  39.75598  1.000 60.58473  ? 253 GLU   A CA  1 
ATOM   1883 C  C   . GLU   A 1 253 ? 29.44912 22.98688  39.03093  1.000 56.61411  ? 253 GLU   A C   1 
ATOM   1884 O  O   . GLU   A 1 253 ? 29.86835 23.83609  38.22997  1.000 60.23892  ? 253 GLU   A O   1 
ATOM   1885 C  CB  . GLU   A 1 253 ? 27.38711 21.86991  40.04167  1.000 72.69922  ? 253 GLU   A CB  1 
ATOM   1886 C  CG  . GLU   A 1 253 ? 26.13652 22.03032  40.90040  1.000 78.62872  ? 253 GLU   A CG  1 
ATOM   1887 C  CD  . GLU   A 1 253 ? 25.33943 20.74549  41.03459  1.000 77.36569  ? 253 GLU   A CD  1 
ATOM   1888 O  OE1 . GLU   A 1 253 ? 25.19443 20.02280  40.02626  1.000 76.17774  ? 253 GLU   A OE1 1 
ATOM   1889 O  OE2 . GLU   A 1 253 ? 24.86024 20.46212  42.15373  1.000 76.19305  ? 253 GLU   A OE2 1 
ATOM   1890 N  N   . GLY   A 1 254 ? 30.10873 21.86417  39.30060  1.000 55.61050  ? 254 GLY   A N   1 
ATOM   1891 C  CA  . GLY   A 1 254 ? 31.45019 21.66936  38.79355  1.000 56.08998  ? 254 GLY   A CA  1 
ATOM   1892 C  C   . GLY   A 1 254 ? 31.47572 21.37331  37.30576  1.000 54.58596  ? 254 GLY   A C   1 
ATOM   1893 O  O   . GLY   A 1 254 ? 30.57168 20.75542  36.74518  1.000 55.40817  ? 254 GLY   A O   1 
ATOM   1894 N  N   . VAL   A 1 255 ? 32.55198 21.81024  36.66289  1.000 53.62301  ? 255 VAL   A N   1 
ATOM   1895 C  CA  . VAL   A 1 255 ? 32.78450 21.54770  35.24594  1.000 53.94122  ? 255 VAL   A CA  1 
ATOM   1896 C  C   . VAL   A 1 255 ? 33.67606 20.31800  35.13868  1.000 62.14109  ? 255 VAL   A C   1 
ATOM   1897 O  O   . VAL   A 1 255 ? 34.78800 20.29842  35.67936  1.000 64.36709  ? 255 VAL   A O   1 
ATOM   1898 C  CB  . VAL   A 1 255 ? 33.42739 22.75676  34.54867  1.000 45.88816  ? 255 VAL   A CB  1 
ATOM   1899 C  CG1 . VAL   A 1 255 ? 33.53930 22.51125  33.05342  1.000 44.92407  ? 255 VAL   A CG1 1 
ATOM   1900 C  CG2 . VAL   A 1 255 ? 32.63007 24.01731  34.82931  1.000 59.98875  ? 255 VAL   A CG2 1 
ATOM   1901 N  N   . TRP   A 1 256 ? 33.18937 19.28612  34.44476  1.000 61.51578  ? 256 TRP   A N   1 
ATOM   1902 C  CA  . TRP   A 1 256 ? 33.87986 18.00725  34.38859  1.000 56.94093  ? 256 TRP   A CA  1 
ATOM   1903 C  C   . TRP   A 1 256 ? 34.33012 17.59545  32.99526  1.000 56.24130  ? 256 TRP   A C   1 
ATOM   1904 O  O   . TRP   A 1 256 ? 35.24092 16.76807  32.88745  1.000 59.71781  ? 256 TRP   A O   1 
ATOM   1905 C  CB  . TRP   A 1 256 ? 32.99073 16.89220  34.96444  1.000 59.56349  ? 256 TRP   A CB  1 
ATOM   1906 C  CG  . TRP   A 1 256 ? 32.70408 17.04043  36.43166  1.000 56.38474  ? 256 TRP   A CG  1 
ATOM   1907 C  CD1 . TRP   A 1 256 ? 33.20610 17.98869  37.27528  1.000 56.33786  ? 256 TRP   A CD1 1 
ATOM   1908 C  CD2 . TRP   A 1 256 ? 31.84777 16.21148  37.22657  1.000 52.99610  ? 256 TRP   A CD2 1 
ATOM   1909 N  NE1 . TRP   A 1 256 ? 32.71495 17.80325  38.54399  1.000 62.44614  ? 256 TRP   A NE1 1 
ATOM   1910 C  CE2 . TRP   A 1 256 ? 31.87904 16.71789  38.54130  1.000 56.87079  ? 256 TRP   A CE2 1 
ATOM   1911 C  CE3 . TRP   A 1 256 ? 31.05785 15.09057  36.95429  1.000 53.26517  ? 256 TRP   A CE3 1 
ATOM   1912 C  CZ2 . TRP   A 1 256 ? 31.15112 16.14222  39.58037  1.000 58.03559  ? 256 TRP   A CZ2 1 
ATOM   1913 C  CZ3 . TRP   A 1 256 ? 30.33675 14.52085  37.98661  1.000 57.87971  ? 256 TRP   A CZ3 1 
ATOM   1914 C  CH2 . TRP   A 1 256 ? 30.38810 15.04706  39.28340  1.000 61.24481  ? 256 TRP   A CH2 1 
ATOM   1915 N  N   . ALA   A 1 257 ? 33.73307 18.13591  31.93543  1.000 52.99906  ? 257 ALA   A N   1 
ATOM   1916 C  CA  . ALA   A 1 257 ? 34.08687 17.76227  30.57393  1.000 62.99406  ? 257 ALA   A CA  1 
ATOM   1917 C  C   . ALA   A 1 257 ? 34.23763 19.00886  29.71390  1.000 63.19937  ? 257 ALA   A C   1 
ATOM   1918 O  O   . ALA   A 1 257 ? 33.51013 19.99152  29.88291  1.000 58.77472  ? 257 ALA   A O   1 
ATOM   1919 C  CB  . ALA   A 1 257 ? 33.03932 16.82660  29.95496  1.000 72.89000  ? 257 ALA   A CB  1 
ATOM   1920 N  N   . LEU   A 1 258 ? 35.18926 18.95604  28.78096  1.000 71.71003  ? 258 LEU   A N   1 
ATOM   1921 C  CA  . LEU   A 1 258 ? 35.48091 20.08068  27.90282  1.000 65.47878  ? 258 LEU   A CA  1 
ATOM   1922 C  C   . LEU   A 1 258 ? 35.74934 19.59313  26.48712  1.000 64.97791  ? 258 LEU   A C   1 
ATOM   1923 O  O   . LEU   A 1 258 ? 36.41513 18.57357  26.28560  1.000 63.83115  ? 258 LEU   A O   1 
ATOM   1924 C  CB  . LEU   A 1 258 ? 36.68907 20.88723  28.39784  1.000 61.96068  ? 258 LEU   A CB  1 
ATOM   1925 C  CG  . LEU   A 1 258 ? 36.49541 21.76859  29.63115  1.000 66.41239  ? 258 LEU   A CG  1 
ATOM   1926 C  CD1 . LEU   A 1 258 ? 37.77106 22.53607  29.92769  1.000 69.11008  ? 258 LEU   A CD1 1 
ATOM   1927 C  CD2 . LEU   A 1 258 ? 35.33038 22.72213  29.43071  1.000 67.58957  ? 258 LEU   A CD2 1 
ATOM   1928 N  N   . GLN   A 1 259 ? 35.22703 20.33511  25.51243  1.000 64.87744  ? 259 GLN   A N   1 
ATOM   1929 C  CA  . GLN   A 1 259 ? 35.51488 20.11345  24.10334  1.000 64.42625  ? 259 GLN   A CA  1 
ATOM   1930 C  C   . GLN   A 1 259 ? 35.65901 21.46636  23.42135  1.000 69.49741  ? 259 GLN   A C   1 
ATOM   1931 O  O   . GLN   A 1 259 ? 35.12174 22.47559  23.88282  1.000 70.15859  ? 259 GLN   A O   1 
ATOM   1932 C  CB  . GLN   A 1 259 ? 34.42445 19.27874  23.41548  1.000 70.28657  ? 259 GLN   A CB  1 
ATOM   1933 C  CG  . GLN   A 1 259 ? 34.42944 17.80305  23.79117  1.000 70.18034  ? 259 GLN   A CG  1 
ATOM   1934 C  CD  . GLN   A 1 259 ? 35.63909 17.06178  23.24928  1.000 68.05568  ? 259 GLN   A CD  1 
ATOM   1935 O  OE1 . GLN   A 1 259 ? 36.31498 17.53380  22.33416  1.000 69.66165  ? 259 GLN   A OE1 1 
ATOM   1936 N  NE2 . GLN   A 1 259 ? 35.91701 15.89247  23.81424  1.000 64.29188  ? 259 GLN   A NE2 1 
ATOM   1937 N  N   . VAL   A 1 260 ? 36.39973 21.48097  22.31474  1.000 72.35117  ? 260 VAL   A N   1 
ATOM   1938 C  CA  . VAL   A 1 260 ? 36.66434 22.70702  21.57299  1.000 67.98559  ? 260 VAL   A CA  1 
ATOM   1939 C  C   . VAL   A 1 260 ? 36.63398 22.39163  20.08389  1.000 76.02018  ? 260 VAL   A C   1 
ATOM   1940 O  O   . VAL   A 1 260 ? 36.94904 21.27568  19.65891  1.000 81.93385  ? 260 VAL   A O   1 
ATOM   1941 C  CB  . VAL   A 1 260 ? 38.01529 23.34404  21.98448  1.000 61.89104  ? 260 VAL   A CB  1 
ATOM   1942 C  CG1 . VAL   A 1 260 ? 39.18654 22.50296  21.49180  1.000 67.92367  ? 260 VAL   A CG1 1 
ATOM   1943 C  CG2 . VAL   A 1 260 ? 38.11828 24.77843  21.48244  1.000 66.10392  ? 260 VAL   A CG2 1 
ATOM   1944 N  N   . ASN   A 1 261 ? 36.23177 23.38075  19.28885  1.000 72.32238  ? 261 ASN   A N   1 
ATOM   1945 C  CA  . ASN   A 1 261 ? 36.18696 23.20886  17.84650  1.000 80.88681  ? 261 ASN   A CA  1 
ATOM   1946 C  C   . ASN   A 1 261 ? 37.59930 23.25578  17.26576  1.000 84.84592  ? 261 ASN   A C   1 
ATOM   1947 O  O   . ASN   A 1 261 ? 38.58749 23.49449  17.96758  1.000 82.44314  ? 261 ASN   A O   1 
ATOM   1948 C  CB  . ASN   A 1 261 ? 35.29192 24.26766  17.20593  1.000 72.81856  ? 261 ASN   A CB  1 
ATOM   1949 C  CG  . ASN   A 1 261 ? 35.84126 25.67080  17.36317  1.000 76.81437  ? 261 ASN   A CG  1 
ATOM   1950 O  OD1 . ASN   A 1 261 ? 36.49189 25.98829  18.35790  1.000 80.73336  ? 261 ASN   A OD1 1 
ATOM   1951 N  ND2 . ASN   A 1 261 ? 35.58003 26.52131  16.37671  1.000 77.52214  ? 261 ASN   A ND2 1 
ATOM   1952 N  N   . ASP   A 1 262 ? 37.68963 23.02693  15.95331  1.000 85.61876  ? 262 ASP   A N   1 
ATOM   1953 C  CA  . ASP   A 1 262 ? 38.99079 22.94462  15.29719  1.000 82.84022  ? 262 ASP   A CA  1 
ATOM   1954 C  C   . ASP   A 1 262 ? 39.72917 24.27622  15.35006  1.000 82.58370  ? 262 ASP   A C   1 
ATOM   1955 O  O   . ASP   A 1 262 ? 40.94536 24.30874  15.57060  1.000 82.17486  ? 262 ASP   A O   1 
ATOM   1956 C  CB  . ASP   A 1 262 ? 38.81723 22.48525  13.84954  1.000 81.77405  ? 262 ASP   A CB  1 
ATOM   1957 C  CG  . ASP   A 1 262 ? 38.18747 21.11057  13.74620  1.000 83.97630  ? 262 ASP   A CG  1 
ATOM   1958 O  OD1 . ASP   A 1 262 ? 37.01488 20.96021  14.14965  1.000 86.88882  ? 262 ASP   A OD1 1 
ATOM   1959 O  OD2 . ASP   A 1 262 ? 38.86384 20.18017  13.26034  1.000 86.76093  ? 262 ASP   A OD2 1 
ATOM   1960 N  N   . ALA   A 1 263 ? 39.01541 25.38329  15.15528  1.000 81.48854  ? 263 ALA   A N   1 
ATOM   1961 C  CA  . ALA   A 1 263 ? 39.63465 26.70243  15.15564  1.000 78.83566  ? 263 ALA   A CA  1 
ATOM   1962 C  C   . ALA   A 1 263 ? 39.92758 27.22749  16.55494  1.000 78.14815  ? 263 ALA   A C   1 
ATOM   1963 O  O   . ALA   A 1 263 ? 40.37218 28.37419  16.68159  1.000 72.26448  ? 263 ALA   A O   1 
ATOM   1964 C  CB  . ALA   A 1 263 ? 38.74536 27.70050  14.40974  1.000 80.75001  ? 263 ALA   A CB  1 
ATOM   1965 N  N   . PHE   A 1 264 ? 39.69473 26.42390  17.59588  1.000 79.22473  ? 264 PHE   A N   1 
ATOM   1966 C  CA  . PHE   A 1 264 ? 39.90775 26.83657  18.98425  1.000 75.88604  ? 264 PHE   A CA  1 
ATOM   1967 C  C   . PHE   A 1 264 ? 39.11398 28.10501  19.29644  1.000 69.51297  ? 264 PHE   A C   1 
ATOM   1968 O  O   . PHE   A 1 264 ? 39.65316 29.10944  19.76525  1.000 62.28207  ? 264 PHE   A O   1 
ATOM   1969 C  CB  . PHE   A 1 264 ? 41.39907 27.02487  19.27984  1.000 78.23663  ? 264 PHE   A CB  1 
ATOM   1970 C  CG  . PHE   A 1 264 ? 41.75231 26.90159  20.73584  1.000 75.49689  ? 264 PHE   A CG  1 
ATOM   1971 C  CD1 . PHE   A 1 264 ? 41.83733 25.65615  21.33723  1.000 74.71478  ? 264 PHE   A CD1 1 
ATOM   1972 C  CD2 . PHE   A 1 264 ? 42.01215 28.02756  21.49969  1.000 74.82351  ? 264 PHE   A CD2 1 
ATOM   1973 C  CE1 . PHE   A 1 264 ? 42.16568 25.53687  22.67517  1.000 66.38190  ? 264 PHE   A CE1 1 
ATOM   1974 C  CE2 . PHE   A 1 264 ? 42.34089 27.91452  22.83698  1.000 71.22127  ? 264 PHE   A CE2 1 
ATOM   1975 C  CZ  . PHE   A 1 264 ? 42.41814 26.66760  23.42512  1.000 66.88587  ? 264 PHE   A CZ  1 
ATOM   1976 N  N   . THR   A 1 265 ? 37.81101 28.05067  19.02056  1.000 72.43587  ? 265 THR   A N   1 
ATOM   1977 C  CA  . THR   A 1 265 ? 36.93596 29.20985  19.15806  1.000 68.83995  ? 265 THR   A CA  1 
ATOM   1978 C  C   . THR   A 1 265 ? 35.84287 28.98416  20.19296  1.000 64.30634  ? 265 THR   A C   1 
ATOM   1979 O  O   . THR   A 1 265 ? 35.72673 29.76968  21.13877  1.000 54.96988  ? 265 THR   A O   1 
ATOM   1980 C  CB  . THR   A 1 265 ? 36.31922 29.56251  17.79858  1.000 75.30329  ? 265 THR   A CB  1 
ATOM   1981 O  OG1 . THR   A 1 265 ? 37.35721 29.92404  16.87922  1.000 84.24189  ? 265 THR   A OG1 1 
ATOM   1982 C  CG2 . THR   A 1 265 ? 35.34747 30.71843  17.94331  1.000 76.74406  ? 265 THR   A CG2 1 
ATOM   1983 N  N   . HIS   A 1 266 ? 35.03222 27.94198  20.03986  1.000 69.68771  ? 266 HIS   A N   1 
ATOM   1984 C  CA  . HIS   A 1 266 ? 33.94644 27.64948  20.96365  1.000 69.02612  ? 266 HIS   A CA  1 
ATOM   1985 C  C   . HIS   A 1 266 ? 34.32222 26.47788  21.85951  1.000 70.24879  ? 266 HIS   A C   1 
ATOM   1986 O  O   . HIS   A 1 266 ? 34.91358 25.49602  21.40102  1.000 76.73688  ? 266 HIS   A O   1 
ATOM   1987 C  CB  . HIS   A 1 266 ? 32.65517 27.33015  20.20813  1.000 67.87752  ? 266 HIS   A CB  1 
ATOM   1988 C  CG  . HIS   A 1 266 ? 32.16060 28.45505  19.35438  1.000 73.47891  ? 266 HIS   A CG  1 
ATOM   1989 N  ND1 . HIS   A 1 266 ? 32.60099 28.65998  18.06471  1.000 71.43772  ? 266 HIS   A ND1 1 
ATOM   1990 C  CD2 . HIS   A 1 266 ? 31.26499 29.43862  19.60702  1.000 79.09021  ? 266 HIS   A CD2 1 
ATOM   1991 C  CE1 . HIS   A 1 266 ? 31.99631 29.71992  17.55882  1.000 79.85169  ? 266 HIS   A CE1 1 
ATOM   1992 N  NE2 . HIS   A 1 266 ? 31.18101 30.21130  18.47444  1.000 82.80795  ? 266 HIS   A NE2 1 
ATOM   1993 N  N   . VAL   A 1 267 ? 33.97227 26.58547  23.13835  1.000 66.55538  ? 267 VAL   A N   1 
ATOM   1994 C  CA  . VAL   A 1 267 ? 34.23090 25.54217  24.12265  1.000 63.53864  ? 267 VAL   A CA  1 
ATOM   1995 C  C   . VAL   A 1 267 ? 32.91461 24.84598  24.44313  1.000 66.10900  ? 267 VAL   A C   1 
ATOM   1996 O  O   . VAL   A 1 267 ? 31.88890 25.50400  24.66142  1.000 64.33916  ? 267 VAL   A O   1 
ATOM   1997 C  CB  . VAL   A 1 267 ? 34.89421 26.10956  25.39188  1.000 52.96529  ? 267 VAL   A CB  1 
ATOM   1998 C  CG1 . VAL   A 1 267 ? 34.05343 27.22476  26.00012  1.000 54.12646  ? 267 VAL   A CG1 1 
ATOM   1999 C  CG2 . VAL   A 1 267 ? 35.14428 25.00178  26.40614  1.000 60.75665  ? 267 VAL   A CG2 1 
ATOM   2000 N  N   . TYR   A 1 268 ? 32.94168 23.51616  24.44673  1.000 66.04839  ? 268 TYR   A N   1 
ATOM   2001 C  CA  . TYR   A 1 268 ? 31.78576 22.68931  24.76924  1.000 60.88076  ? 268 TYR   A CA  1 
ATOM   2002 C  C   . TYR   A 1 268 ? 32.00167 22.10274  26.15659  1.000 60.22823  ? 268 TYR   A C   1 
ATOM   2003 O  O   . TYR   A 1 268 ? 32.94456 21.33281  26.36738  1.000 63.25141  ? 268 TYR   A O   1 
ATOM   2004 C  CB  . TYR   A 1 268 ? 31.59460 21.58202  23.73198  1.000 66.17316  ? 268 TYR   A CB  1 
ATOM   2005 C  CG  . TYR   A 1 268 ? 31.38519 22.08596  22.31954  1.000 70.01232  ? 268 TYR   A CG  1 
ATOM   2006 C  CD1 . TYR   A 1 268 ? 32.45445 22.53792  21.55518  1.000 71.35685  ? 268 TYR   A CD1 1 
ATOM   2007 C  CD2 . TYR   A 1 268 ? 30.12005 22.10132  21.74746  1.000 69.41110  ? 268 TYR   A CD2 1 
ATOM   2008 C  CE1 . TYR   A 1 268 ? 32.26884 22.99816  20.26577  1.000 69.48446  ? 268 TYR   A CE1 1 
ATOM   2009 C  CE2 . TYR   A 1 268 ? 29.92499 22.55715  20.45640  1.000 68.49574  ? 268 TYR   A CE2 1 
ATOM   2010 C  CZ  . TYR   A 1 268 ? 31.00284 23.00509  19.72101  1.000 71.83061  ? 268 TYR   A CZ  1 
ATOM   2011 O  OH  . TYR   A 1 268 ? 30.81535 23.46138  18.43633  1.000 77.58147  ? 268 TYR   A OH  1 
ATOM   2012 N  N   . SER   A 1 269 ? 31.13388 22.46614  27.09604  1.000 58.30163  ? 269 SER   A N   1 
ATOM   2013 C  CA  . SER   A 1 269 ? 31.35449 22.16345  28.50131  1.000 58.35607  ? 269 SER   A CA  1 
ATOM   2014 C  C   . SER   A 1 269 ? 30.11302 21.55186  29.13298  1.000 61.77608  ? 269 SER   A C   1 
ATOM   2015 O  O   . SER   A 1 269 ? 28.97953 21.86726  28.75861  1.000 63.61752  ? 269 SER   A O   1 
ATOM   2016 C  CB  . SER   A 1 269 ? 31.75522 23.41978  29.28016  1.000 61.81746  ? 269 SER   A CB  1 
ATOM   2017 O  OG  . SER   A 1 269 ? 30.73419 24.40092  29.22435  1.000 64.93633  ? 269 SER   A OG  1 
ATOM   2018 N  N   . GLY   A 1 270 ? 30.35319 20.67654  30.10701  1.000 62.77734  ? 270 GLY   A N   1 
ATOM   2019 C  CA  . GLY   A 1 270 ? 29.31505 20.06783  30.91501  1.000 58.34674  ? 270 GLY   A CA  1 
ATOM   2020 C  C   . GLY   A 1 270 ? 29.89828 19.65670  32.25007  1.000 56.34329  ? 270 GLY   A C   1 
ATOM   2021 O  O   . GLY   A 1 270 ? 31.07835 19.87593  32.53247  1.000 62.50960  ? 270 GLY   A O   1 
ATOM   2022 N  N   . GLY   A 1 271 ? 29.05566 19.05079  33.08187  1.000 52.19322  ? 271 GLY   A N   1 
ATOM   2023 C  CA  . GLY   A 1 271 ? 29.52452 18.60558  34.38012  1.000 57.49000  ? 271 GLY   A CA  1 
ATOM   2024 C  C   . GLY   A 1 271 ? 28.44363 18.09282  35.30758  1.000 65.47312  ? 271 GLY   A C   1 
ATOM   2025 O  O   . GLY   A 1 271 ? 27.54068 17.36722  34.87916  1.000 66.03791  ? 271 GLY   A O   1 
ATOM   2026 N  N   . ARG   A 1 272 ? 28.53628 18.45855  36.58962  1.000 66.50056  ? 272 ARG   A N   1 
ATOM   2027 C  CA  . ARG   A 1 272 ? 27.54974 18.00723  37.56667  1.000 69.10426  ? 272 ARG   A CA  1 
ATOM   2028 C  C   . ARG   A 1 272 ? 26.15486 18.49374  37.19443  1.000 71.27017  ? 272 ARG   A C   1 
ATOM   2029 O  O   . ARG   A 1 272 ? 25.19464 17.71491  37.18399  1.000 68.26087  ? 272 ARG   A O   1 
ATOM   2030 C  CB  . ARG   A 1 272 ? 27.94013 18.48545  38.96534  1.000 68.72138  ? 272 ARG   A CB  1 
ATOM   2031 C  CG  . ARG   A 1 272 ? 27.58851 17.50744  40.07551  1.000 70.70263  ? 272 ARG   A CG  1 
ATOM   2032 C  CD  . ARG   A 1 272 ? 27.99327 18.04365  41.44014  1.000 71.25981  ? 272 ARG   A CD  1 
ATOM   2033 N  NE  . ARG   A 1 272 ? 27.91533 17.01756  42.47348  1.000 73.30579  ? 272 ARG   A NE  1 
ATOM   2034 C  CZ  . ARG   A 1 272 ? 26.80905 16.69524  43.13005  1.000 77.75761  ? 272 ARG   A CZ  1 
ATOM   2035 N  NH1 . ARG   A 1 272 ? 25.65759 17.29807  42.88276  1.000 79.18842  ? 272 ARG   A NH1 1 
ATOM   2036 N  NH2 . ARG   A 1 272 ? 26.85882 15.74236  44.05680  1.000 75.64966  ? 272 ARG   A NH2 1 
ATOM   2037 N  N   . ASP   A 1 273 ? 26.02236 19.78144  36.88720  1.000 72.66722  ? 273 ASP   A N   1 
ATOM   2038 C  CA  . ASP   A 1 273 ? 24.79595 20.27355  36.27609  1.000 67.09765  ? 273 ASP   A CA  1 
ATOM   2039 C  C   . ASP   A 1 273 ? 24.71986 19.74415  34.84962  1.000 67.96868  ? 273 ASP   A C   1 
ATOM   2040 O  O   . ASP   A 1 273 ? 25.60866 20.00723  34.03322  1.000 68.28325  ? 273 ASP   A O   1 
ATOM   2041 C  CB  . ASP   A 1 273 ? 24.75260 21.80037  36.30414  1.000 63.76829  ? 273 ASP   A CB  1 
ATOM   2042 C  CG  . ASP   A 1 273 ? 25.99696 22.43500  35.71245  1.000 64.34704  ? 273 ASP   A CG  1 
ATOM   2043 O  OD1 . ASP   A 1 273 ? 27.10175 21.89291  35.92272  1.000 64.21722  ? 273 ASP   A OD1 1 
ATOM   2044 O  OD2 . ASP   A 1 273 ? 25.86795 23.47596  35.03381  1.000 67.37041  ? 273 ASP   A OD2 1 
ATOM   2045 N  N   . ARG   A 1 274 ? 23.66559 18.98436  34.55128  1.000 66.87098  ? 274 ARG   A N   1 
ATOM   2046 C  CA  . ARG   A 1 274 ? 23.60543 18.23859  33.29878  1.000 70.54714  ? 274 ARG   A CA  1 
ATOM   2047 C  C   . ARG   A 1 274 ? 23.53753 19.13737  32.07090  1.000 72.80491  ? 274 ARG   A C   1 
ATOM   2048 O  O   . ARG   A 1 274 ? 23.56345 18.62441  30.94675  1.000 77.33582  ? 274 ARG   A O   1 
ATOM   2049 C  CB  . ARG   A 1 274 ? 22.40677 17.28810  33.31598  1.000 72.19603  ? 274 ARG   A CB  1 
ATOM   2050 C  CG  . ARG   A 1 274 ? 22.29562 16.44871  34.58173  1.000 70.60744  ? 274 ARG   A CG  1 
ATOM   2051 C  CD  . ARG   A 1 274 ? 21.34871 17.08548  35.58797  1.000 70.90404  ? 274 ARG   A CD  1 
ATOM   2052 N  NE  . ARG   A 1 274 ? 21.53606 16.54455  36.92815  1.000 72.67022  ? 274 ARG   A NE  1 
ATOM   2053 C  CZ  . ARG   A 1 274 ? 20.94974 15.44546  37.38134  1.000 71.41670  ? 274 ARG   A CZ  1 
ATOM   2054 N  NH1 . ARG   A 1 274 ? 20.12492 14.73986  36.62500  1.000 65.44383  ? 274 ARG   A NH1 1 
ATOM   2055 N  NH2 . ARG   A 1 274 ? 21.19939 15.04268  38.62383  1.000 75.60214  ? 274 ARG   A NH2 1 
ATOM   2056 N  N   . LYS   A 1 275 ? 23.45926 20.45103  32.25376  1.000 64.09460  ? 275 LYS   A N   1 
ATOM   2057 C  CA  . LYS   A 1 275 ? 23.40080 21.36914  31.12702  1.000 60.25141  ? 275 LYS   A CA  1 
ATOM   2058 C  C   . LYS   A 1 275 ? 24.74504 21.42710  30.41095  1.000 57.50809  ? 275 LYS   A C   1 
ATOM   2059 O  O   . LYS   A 1 275 ? 25.80341 21.49181  31.04253  1.000 57.11818  ? 275 LYS   A O   1 
ATOM   2060 C  CB  . LYS   A 1 275 ? 22.99369 22.75772  31.61478  1.000 70.55964  ? 275 LYS   A CB  1 
ATOM   2061 C  CG  . LYS   A 1 275 ? 21.73378 22.74292  32.46480  1.000 77.31807  ? 275 LYS   A CG  1 
ATOM   2062 C  CD  . LYS   A 1 275 ? 21.71432 23.88426  33.46567  1.000 83.64224  ? 275 LYS   A CD  1 
ATOM   2063 C  CE  . LYS   A 1 275 ? 20.62464 23.67311  34.50533  1.000 83.96658  ? 275 LYS   A CE  1 
ATOM   2064 N  NZ  . LYS   A 1 275 ? 20.78259 22.37055  35.21260  1.000 71.17212  ? 275 LYS   A NZ  1 
ATOM   2065 N  N   . ILE   A 1 276 ? 24.69771 21.39770  29.08145  1.000 58.06979  ? 276 ILE   A N   1 
ATOM   2066 C  CA  . ILE   A 1 276 ? 25.88723 21.44126  28.24059  1.000 57.27296  ? 276 ILE   A CA  1 
ATOM   2067 C  C   . ILE   A 1 276 ? 25.83433 22.71546  27.41134  1.000 66.04957  ? 276 ILE   A C   1 
ATOM   2068 O  O   . ILE   A 1 276 ? 24.79011 23.04563  26.83699  1.000 68.97175  ? 276 ILE   A O   1 
ATOM   2069 C  CB  . ILE   A 1 276 ? 25.98801 20.19733  27.33972  1.000 51.17877  ? 276 ILE   A CB  1 
ATOM   2070 C  CG1 . ILE   A 1 276 ? 26.04734 18.93221  28.19757  1.000 57.12360  ? 276 ILE   A CG1 1 
ATOM   2071 C  CG2 . ILE   A 1 276 ? 27.20506 20.28776  26.43228  1.000 53.12516  ? 276 ILE   A CG2 1 
ATOM   2072 C  CD1 . ILE   A 1 276 ? 26.08285 17.65402  27.39874  1.000 60.24166  ? 276 ILE   A CD1 1 
ATOM   2073 N  N   . TYR   A 1 277 ? 26.95726 23.42620  27.34975  1.000 67.07161  ? 277 TYR   A N   1 
ATOM   2074 C  CA  . TYR   A 1 277 ? 27.01191 24.73453  26.71308  1.000 65.63059  ? 277 TYR   A CA  1 
ATOM   2075 C  C   . TYR   A 1 277 ? 28.11058 24.78153  25.66305  1.000 64.22252  ? 277 TYR   A C   1 
ATOM   2076 O  O   . TYR   A 1 277 ? 29.20319 24.24401  25.86566  1.000 62.87659  ? 277 TYR   A O   1 
ATOM   2077 C  CB  . TYR   A 1 277 ? 27.24663 25.84465  27.74394  1.000 64.22693  ? 277 TYR   A CB  1 
ATOM   2078 C  CG  . TYR   A 1 277 ? 26.13691 25.98269  28.75830  1.000 65.51382  ? 277 TYR   A CG  1 
ATOM   2079 C  CD1 . TYR   A 1 277 ? 25.03187 26.78266  28.50152  1.000 68.16973  ? 277 TYR   A CD1 1 
ATOM   2080 C  CD2 . TYR   A 1 277 ? 26.19451 25.31472  29.97371  1.000 69.05211  ? 277 TYR   A CD2 1 
ATOM   2081 C  CE1 . TYR   A 1 277 ? 24.01444 26.91309  29.42649  1.000 71.04044  ? 277 TYR   A CE1 1 
ATOM   2082 C  CE2 . TYR   A 1 277 ? 25.18261 25.43919  30.90512  1.000 70.91304  ? 277 TYR   A CE2 1 
ATOM   2083 C  CZ  . TYR   A 1 277 ? 24.09483 26.23908  30.62638  1.000 73.55470  ? 277 TYR   A CZ  1 
ATOM   2084 O  OH  . TYR   A 1 277 ? 23.08420 26.36573  31.55133  1.000 81.59379  ? 277 TYR   A OH  1 
ATOM   2085 N  N   . CYS   A 1 278 ? 27.80872 25.43333  24.54365  1.000 63.87975  ? 278 CYS   A N   1 
ATOM   2086 C  CA  . CYS   A 1 278 ? 28.78250 25.76653  23.50648  1.000 59.61035  ? 278 CYS   A CA  1 
ATOM   2087 C  C   . CYS   A 1 278 ? 28.98609 27.27813  23.57419  1.000 59.05708  ? 278 CYS   A C   1 
ATOM   2088 O  O   . CYS   A 1 278 ? 28.23666 28.04909  22.97238  1.000 64.01650  ? 278 CYS   A O   1 
ATOM   2089 C  CB  . CYS   A 1 278 ? 28.30515 25.32103  22.12779  1.000 65.39592  ? 278 CYS   A CB  1 
ATOM   2090 S  SG  . CYS   A 1 278 ? 29.30091 25.95619  20.75819  1.000 78.46965  ? 278 CYS   A SG  1 
ATOM   2091 N  N   . THR   A 1 279 ? 30.00664 27.69637  24.31603  1.000 60.61681  ? 279 THR   A N   1 
ATOM   2092 C  CA  . THR   A 1 279 ? 30.23830 29.10326  24.61668  1.000 57.61129  ? 279 THR   A CA  1 
ATOM   2093 C  C   . THR   A 1 279 ? 31.40332 29.62980  23.79036  1.000 57.92943  ? 279 THR   A C   1 
ATOM   2094 O  O   . THR   A 1 279 ? 32.44860 28.97851  23.69655  1.000 64.99736  ? 279 THR   A O   1 
ATOM   2095 C  CB  . THR   A 1 279 ? 30.52033 29.30378  26.10760  1.000 59.86171  ? 279 THR   A CB  1 
ATOM   2096 O  OG1 . THR   A 1 279 ? 29.48051 28.68976  26.87901  1.000 65.53589  ? 279 THR   A OG1 1 
ATOM   2097 C  CG2 . THR   A 1 279 ? 30.58189 30.78670  26.44352  1.000 61.30677  ? 279 THR   A CG2 1 
ATOM   2098 N  N   . ASP   A 1 280 ? 31.22042 30.80772  23.19840  1.000 56.88964  ? 280 ASP   A N   1 
ATOM   2099 C  CA  . ASP   A 1 280 ? 32.27985 31.44946  22.43321  1.000 64.46930  ? 280 ASP   A CA  1 
ATOM   2100 C  C   . ASP   A 1 280 ? 33.31422 32.04416  23.38070  1.000 63.50283  ? 280 ASP   A C   1 
ATOM   2101 O  O   . ASP   A 1 280 ? 32.97551 32.83591  24.26594  1.000 60.59128  ? 280 ASP   A O   1 
ATOM   2102 C  CB  . ASP   A 1 280 ? 31.70024 32.53555  21.52680  1.000 67.73325  ? 280 ASP   A CB  1 
ATOM   2103 C  CG  . ASP   A 1 280 ? 32.74672 33.16601  20.62771  1.000 66.90677  ? 280 ASP   A CG  1 
ATOM   2104 O  OD1 . ASP   A 1 280 ? 33.19954 32.49294  19.67903  1.000 72.19753  ? 280 ASP   A OD1 1 
ATOM   2105 O  OD2 . ASP   A 1 280 ? 33.11492 34.33506  20.86810  1.000 62.08381  ? 280 ASP   A OD2 1 
ATOM   2106 N  N   . LEU   A 1 281 ? 34.57870 31.65695  23.19449  1.000 67.90368  ? 281 LEU   A N   1 
ATOM   2107 C  CA  . LEU   A 1 281 ? 35.64061 32.15843  24.06109  1.000 67.62980  ? 281 LEU   A CA  1 
ATOM   2108 C  C   . LEU   A 1 281 ? 35.86241 33.65418  23.87811  1.000 67.37237  ? 281 LEU   A C   1 
ATOM   2109 O  O   . LEU   A 1 281 ? 36.20248 34.35084  24.84110  1.000 70.11940  ? 281 LEU   A O   1 
ATOM   2110 C  CB  . LEU   A 1 281 ? 36.93924 31.39623  23.79631  1.000 69.96173  ? 281 LEU   A CB  1 
ATOM   2111 C  CG  . LEU   A 1 281 ? 36.94013 29.90234  24.12573  1.000 65.98096  ? 281 LEU   A CG  1 
ATOM   2112 C  CD1 . LEU   A 1 281 ? 38.21802 29.24526  23.62890  1.000 72.28533  ? 281 LEU   A CD1 1 
ATOM   2113 C  CD2 . LEU   A 1 281 ? 36.77068 29.68424  25.61899  1.000 65.03197  ? 281 LEU   A CD2 1 
ATOM   2114 N  N   . ARG   A 1 282 ? 35.67612 34.16483  22.65959  1.000 69.68374  ? 282 ARG   A N   1 
ATOM   2115 C  CA  . ARG   A 1 282 ? 35.89270 35.58341  22.40403  1.000 72.01862  ? 282 ARG   A CA  1 
ATOM   2116 C  C   . ARG   A 1 282 ? 34.77520 36.45010  22.97006  1.000 67.78901  ? 282 ARG   A C   1 
ATOM   2117 O  O   . ARG   A 1 282 ? 34.97300 37.65684  23.14862  1.000 61.80106  ? 282 ARG   A O   1 
ATOM   2118 C  CB  . ARG   A 1 282 ? 36.03997 35.81876  20.90086  1.000 69.03753  ? 282 ARG   A CB  1 
ATOM   2119 C  CG  . ARG   A 1 282 ? 36.98156 34.83171  20.22642  1.000 62.92809  ? 282 ARG   A CG  1 
ATOM   2120 C  CD  . ARG   A 1 282 ? 36.32796 34.17468  19.02143  1.000 59.60513  ? 282 ARG   A CD  1 
ATOM   2121 N  NE  . ARG   A 1 282 ? 36.30058 35.05908  17.86288  1.000 88.44387  ? 282 ARG   A NE  1 
ATOM   2122 C  CZ  . ARG   A 1 282 ? 35.67585 34.78644  16.72528  1.000 93.25441  ? 282 ARG   A CZ  1 
ATOM   2123 N  NH1 . ARG   A 1 282 ? 34.98792 33.66809  16.56476  1.000 80.66455  ? 282 ARG   A NH1 1 
ATOM   2124 N  NH2 . ARG   A 1 282 ? 35.73887 35.66057  15.72479  1.000 91.69822  ? 282 ARG   A NH2 1 
ATOM   2125 N  N   . ASN   A 1 283 ? 33.61416 35.86464  23.25643  1.000 67.93387  ? 283 ASN   A N   1 
ATOM   2126 C  CA  . ASN   A 1 283 ? 32.50221 36.57833  23.86995  1.000 59.44557  ? 283 ASN   A CA  1 
ATOM   2127 C  C   . ASN   A 1 283 ? 31.63201 35.59001  24.63691  1.000 64.08937  ? 283 ASN   A C   1 
ATOM   2128 O  O   . ASN   A 1 283 ? 30.89541 34.80523  24.02539  1.000 67.16583  ? 283 ASN   A O   1 
ATOM   2129 C  CB  . ASN   A 1 283 ? 31.67950 37.31869  22.81385  1.000 60.15630  ? 283 ASN   A CB  1 
ATOM   2130 C  CG  . ASN   A 1 283 ? 30.58001 38.17034  23.42138  1.000 68.77596  ? 283 ASN   A CG  1 
ATOM   2131 O  OD1 . ASN   A 1 283 ? 30.59236 38.46208  24.61737  1.000 70.98619  ? 283 ASN   A OD1 1 
ATOM   2132 N  ND2 . ASN   A 1 283 ? 29.62378 38.57837  22.59546  1.000 71.83844  ? 283 ASN   A ND2 1 
ATOM   2133 N  N   . PRO   A 1 284 ? 31.68889 35.59505  25.97232  1.000 68.00731  ? 284 PRO   A N   1 
ATOM   2134 C  CA  . PRO   A 1 284 ? 30.90782 34.61434  26.74388  1.000 63.47064  ? 284 PRO   A CA  1 
ATOM   2135 C  C   . PRO   A 1 284 ? 29.40670 34.80913  26.63773  1.000 65.17676  ? 284 PRO   A C   1 
ATOM   2136 O  O   . PRO   A 1 284 ? 28.65633 33.88341  26.97150  1.000 65.15688  ? 284 PRO   A O   1 
ATOM   2137 C  CB  . PRO   A 1 284 ? 31.39669 34.83091  28.18164  1.000 65.13835  ? 284 PRO   A CB  1 
ATOM   2138 C  CG  . PRO   A 1 284 ? 31.86304 36.24872  28.20015  1.000 75.36753  ? 284 PRO   A CG  1 
ATOM   2139 C  CD  . PRO   A 1 284 ? 32.45288 36.50491  26.84249  1.000 76.69178  ? 284 PRO   A CD  1 
ATOM   2140 N  N   . ASP   A 1 285 ? 28.94347 35.97701  26.18655  1.000 66.41172  ? 285 ASP   A N   1 
ATOM   2141 C  CA  . ASP   A 1 285 ? 27.51328 36.19421  26.01005  1.000 64.61369  ? 285 ASP   A CA  1 
ATOM   2142 C  C   . ASP   A 1 285 ? 26.93364 35.33952  24.89101  1.000 63.74628  ? 285 ASP   A C   1 
ATOM   2143 O  O   . ASP   A 1 285 ? 25.70986 35.18624  24.81554  1.000 64.32969  ? 285 ASP   A O   1 
ATOM   2144 C  CB  . ASP   A 1 285 ? 27.23750 37.67192  25.73056  1.000 63.09657  ? 285 ASP   A CB  1 
ATOM   2145 C  CG  . ASP   A 1 285 ? 27.70117 38.57553  26.85522  1.000 63.48151  ? 285 ASP   A CG  1 
ATOM   2146 O  OD1 . ASP   A 1 285 ? 28.10795 38.05120  27.91339  1.000 67.41854  ? 285 ASP   A OD1 1 
ATOM   2147 O  OD2 . ASP   A 1 285 ? 27.66129 39.81148  26.67888  1.000 59.53774  ? 285 ASP   A OD2 1 
ATOM   2148 N  N   . ILE   A 1 286 ? 27.77997 34.78247  24.02573  1.000 64.46561  ? 286 ILE   A N   1 
ATOM   2149 C  CA  . ILE   A 1 286 ? 27.32501 33.94561  22.92187  1.000 61.48797  ? 286 ILE   A CA  1 
ATOM   2150 C  C   . ILE   A 1 286 ? 27.44428 32.48118  23.32265  1.000 60.39650  ? 286 ILE   A C   1 
ATOM   2151 O  O   . ILE   A 1 286 ? 28.33252 31.76441  22.84657  1.000 59.66326  ? 286 ILE   A O   1 
ATOM   2152 C  CB  . ILE   A 1 286 ? 28.12251 34.23348  21.63661  1.000 63.84483  ? 286 ILE   A CB  1 
ATOM   2153 C  CG1 . ILE   A 1 286 ? 28.32427 35.73852  21.45962  1.000 64.29700  ? 286 ILE   A CG1 1 
ATOM   2154 C  CG2 . ILE   A 1 286 ? 27.40454 33.65915  20.42545  1.000 61.84302  ? 286 ILE   A CG2 1 
ATOM   2155 C  CD1 . ILE   A 1 286 ? 29.18023 36.10234  20.26650  1.000 66.42743  ? 286 ILE   A CD1 1 
ATOM   2156 N  N   . ARG   A 1 287 ? 26.55671 32.03017  24.20654  1.000 62.56211  ? 287 ARG   A N   1 
ATOM   2157 C  CA  . ARG   A 1 287 ? 26.51426 30.64047  24.63684  1.000 66.01501  ? 287 ARG   A CA  1 
ATOM   2158 C  C   . ARG   A 1 287 ? 25.11671 30.08390  24.41254  1.000 61.60054  ? 287 ARG   A C   1 
ATOM   2159 O  O   . ARG   A 1 287 ? 24.12147 30.79646  24.57231  1.000 67.15422  ? 287 ARG   A O   1 
ATOM   2160 C  CB  . ARG   A 1 287 ? 26.90731 30.49183  26.11356  1.000 71.45671  ? 287 ARG   A CB  1 
ATOM   2161 C  CG  . ARG   A 1 287 ? 26.16349 31.41532  27.06539  1.000 72.13319  ? 287 ARG   A CG  1 
ATOM   2162 C  CD  . ARG   A 1 287 ? 26.27143 30.91701  28.49819  1.000 71.55198  ? 287 ARG   A CD  1 
ATOM   2163 N  NE  . ARG   A 1 287 ? 25.90247 31.94017  29.46869  1.000 92.49321  ? 287 ARG   A NE  1 
ATOM   2164 C  CZ  . ARG   A 1 287 ? 25.69463 31.70700  30.75724  1.000 99.04026  ? 287 ARG   A CZ  1 
ATOM   2165 N  NH1 . ARG   A 1 287 ? 25.77628 30.48620  31.26017  1.000 92.59859  ? 287 ARG   A NH1 1 
ATOM   2166 N  NH2 . ARG   A 1 287 ? 25.39397 32.72341  31.56065  1.000 98.78767  ? 287 ARG   A NH2 1 
ATOM   2167 N  N   . VAL   A 1 288 ? 25.04744 28.80815  24.04074  1.000 54.50983  ? 288 VAL   A N   1 
ATOM   2168 C  CA  . VAL   A 1 288 ? 23.78813 28.13705  23.74395  1.000 55.55882  ? 288 VAL   A CA  1 
ATOM   2169 C  C   . VAL   A 1 288 ? 23.70013 26.87603  24.58970  1.000 56.00523  ? 288 VAL   A C   1 
ATOM   2170 O  O   . VAL   A 1 288 ? 24.64806 26.08355  24.63123  1.000 57.75015  ? 288 VAL   A O   1 
ATOM   2171 C  CB  . VAL   A 1 288 ? 23.66165 27.78848  22.24822  1.000 61.30238  ? 288 VAL   A CB  1 
ATOM   2172 C  CG1 . VAL   A 1 288 ? 22.33774 27.08955  21.97785  1.000 60.79529  ? 288 VAL   A CG1 1 
ATOM   2173 C  CG2 . VAL   A 1 288 ? 23.79649 29.03983  21.39488  1.000 70.58350  ? 288 VAL   A CG2 1 
ATOM   2174 N  N   . LEU   A 1 289 ? 22.56894 26.69426  25.26491  1.000 59.54757  ? 289 LEU   A N   1 
ATOM   2175 C  CA  . LEU   A 1 289 ? 22.30382 25.46005  25.99866  1.000 62.74140  ? 289 LEU   A CA  1 
ATOM   2176 C  C   . LEU   A 1 289 ? 22.02732 24.35285  24.99147  1.000 64.65890  ? 289 LEU   A C   1 
ATOM   2177 O  O   . LEU   A 1 289 ? 20.95715 24.30154  24.38119  1.000 69.84315  ? 289 LEU   A O   1 
ATOM   2178 C  CB  . LEU   A 1 289 ? 21.13155 25.64435  26.95528  1.000 69.74256  ? 289 LEU   A CB  1 
ATOM   2179 C  CG  . LEU   A 1 289 ? 20.60962 24.37599  27.63664  1.000 64.78959  ? 289 LEU   A CG  1 
ATOM   2180 C  CD1 . LEU   A 1 289 ? 21.72813 23.65322  28.36912  1.000 62.02700  ? 289 LEU   A CD1 1 
ATOM   2181 C  CD2 . LEU   A 1 289 ? 19.46781 24.70384  28.58720  1.000 77.53271  ? 289 LEU   A CD2 1 
ATOM   2182 N  N   . ILE   A 1 290 ? 23.00235 23.46242  24.80671  1.000 62.37779  ? 290 ILE   A N   1 
ATOM   2183 C  CA  . ILE   A 1 290 ? 22.83809 22.37094  23.85244  1.000 61.80673  ? 290 ILE   A CA  1 
ATOM   2184 C  C   . ILE   A 1 290 ? 21.76212 21.40443  24.33108  1.000 63.22716  ? 290 ILE   A C   1 
ATOM   2185 O  O   . ILE   A 1 290 ? 20.79083 21.12862  23.61697  1.000 65.57029  ? 290 ILE   A O   1 
ATOM   2186 C  CB  . ILE   A 1 290 ? 24.18025 21.65509  23.62050  1.000 57.04974  ? 290 ILE   A CB  1 
ATOM   2187 C  CG1 . ILE   A 1 290 ? 25.22639 22.64444  23.10172  1.000 54.43166  ? 290 ILE   A CG1 1 
ATOM   2188 C  CG2 . ILE   A 1 290 ? 24.00353 20.49781  22.65017  1.000 55.26480  ? 290 ILE   A CG2 1 
ATOM   2189 C  CD1 . ILE   A 1 290 ? 26.59501 22.03498  22.89187  1.000 57.32763  ? 290 ILE   A CD1 1 
ATOM   2190 N  N   . CYS   A 1 291 ? 21.91308 20.88539  25.54703  1.000 61.20004  ? 291 CYS   A N   1 
ATOM   2191 C  CA  . CYS   A 1 291 ? 20.95328 19.94799  26.11453  1.000 62.62073  ? 291 CYS   A CA  1 
ATOM   2192 C  C   . CYS   A 1 291 ? 21.26878 19.75828  27.58959  1.000 62.86680  ? 291 CYS   A C   1 
ATOM   2193 O  O   . CYS   A 1 291 ? 22.39974 19.97437  28.03430  1.000 66.19031  ? 291 CYS   A O   1 
ATOM   2194 C  CB  . CYS   A 1 291 ? 20.98671 18.59697  25.39425  1.000 66.93323  ? 291 CYS   A CB  1 
ATOM   2195 S  SG  . CYS   A 1 291 ? 22.52589 17.68666  25.64440  1.000 66.01871  ? 291 CYS   A SG  1 
ATOM   2196 N  N   . GLU   A 1 292 ? 20.25414 19.33873  28.33904  1.000 62.45207  ? 292 GLU   A N   1 
ATOM   2197 C  CA  . GLU   A 1 292 ? 20.40751 18.94368  29.73449  1.000 68.76667  ? 292 GLU   A CA  1 
ATOM   2198 C  C   . GLU   A 1 292 ? 20.18582 17.43863  29.81655  1.000 69.68585  ? 292 GLU   A C   1 
ATOM   2199 O  O   . GLU   A 1 292 ? 19.05984 16.96138  29.63910  1.000 75.11601  ? 292 GLU   A O   1 
ATOM   2200 C  CB  . GLU   A 1 292 ? 19.43146 19.69587  30.63635  1.000 71.75406  ? 292 GLU   A CB  1 
ATOM   2201 C  CG  . GLU   A 1 292 ? 19.47470 19.24764  32.08953  1.000 79.11425  ? 292 GLU   A CG  1 
ATOM   2202 C  CD  . GLU   A 1 292 ? 18.46962 19.97545  32.95950  1.000 89.50117  ? 292 GLU   A CD  1 
ATOM   2203 O  OE1 . GLU   A 1 292 ? 17.99206 21.05304  32.54583  1.000 82.52413  ? 292 GLU   A OE1 1 
ATOM   2204 O  OE2 . GLU   A 1 292 ? 18.15494 19.46701  34.05656  1.000 100.04596 ? 292 GLU   A OE2 1 
ATOM   2205 N  N   . GLU   A 1 293 ? 21.25812 16.69580  30.08018  1.000 67.02155  ? 293 GLU   A N   1 
ATOM   2206 C  CA  . GLU   A 1 293 ? 21.17733 15.24564  30.16203  1.000 65.66152  ? 293 GLU   A CA  1 
ATOM   2207 C  C   . GLU   A 1 293 ? 20.37556 14.82393  31.39346  1.000 70.79311  ? 293 GLU   A C   1 
ATOM   2208 O  O   . GLU   A 1 293 ? 19.95200 15.64408  32.21294  1.000 72.82409  ? 293 GLU   A O   1 
ATOM   2209 C  CB  . GLU   A 1 293 ? 22.57840 14.63812  30.19113  1.000 62.89478  ? 293 GLU   A CB  1 
ATOM   2210 C  CG  . GLU   A 1 293 ? 23.14425 14.27983  28.82423  1.000 64.45261  ? 293 GLU   A CG  1 
ATOM   2211 C  CD  . GLU   A 1 293 ? 22.67907 12.91908  28.33479  1.000 64.35976  ? 293 GLU   A CD  1 
ATOM   2212 O  OE1 . GLU   A 1 293 ? 21.67581 12.39771  28.86653  1.000 66.83935  ? 293 GLU   A OE1 1 
ATOM   2213 O  OE2 . GLU   A 1 293 ? 23.32255 12.36547  27.41861  1.000 59.19259  ? 293 GLU   A OE2 1 
ATOM   2214 N  N   . LYS   A 1 294 ? 20.15901 13.51354  31.51946  1.000 73.18643  ? 294 LYS   A N   1 
ATOM   2215 C  CA  . LYS   A 1 294 ? 19.45994 12.99103  32.68706  1.000 70.34468  ? 294 LYS   A CA  1 
ATOM   2216 C  C   . LYS   A 1 294 ? 20.39779 12.80164  33.87171  1.000 76.56230  ? 294 LYS   A C   1 
ATOM   2217 O  O   . LYS   A 1 294 ? 19.97265 12.94647  35.02344  1.000 76.68581  ? 294 LYS   A O   1 
ATOM   2218 C  CB  . LYS   A 1 294 ? 18.77267 11.66748  32.34519  1.000 63.72830  ? 294 LYS   A CB  1 
ATOM   2219 C  CG  . LYS   A 1 294 ? 17.72443 11.77391  31.24938  1.000 75.43159  ? 294 LYS   A CG  1 
ATOM   2220 C  CD  . LYS   A 1 294 ? 16.91739 10.49028  31.12991  1.000 88.70610  ? 294 LYS   A CD  1 
ATOM   2221 C  CE  . LYS   A 1 294 ? 15.80312 10.63403  30.10581  1.000 90.80069  ? 294 LYS   A CE  1 
ATOM   2222 N  NZ  . LYS   A 1 294 ? 14.91308 9.44075   30.07998  1.000 72.34420  ? 294 LYS   A NZ  1 
ATOM   2223 N  N   . ALA   A 1 295 ? 21.66070 12.48797  33.61287  1.000 78.86350  ? 295 ALA   A N   1 
ATOM   2224 C  CA  . ALA   A 1 295 ? 22.67080 12.26314  34.63140  1.000 75.62842  ? 295 ALA   A CA  1 
ATOM   2225 C  C   . ALA   A 1 295 ? 23.80103 13.27344  34.47993  1.000 69.24686  ? 295 ALA   A C   1 
ATOM   2226 O  O   . ALA   A 1 295 ? 23.97734 13.86196  33.40614  1.000 74.86700  ? 295 ALA   A O   1 
ATOM   2227 C  CB  . ALA   A 1 295 ? 23.22900 10.83542  34.53458  1.000 75.29588  ? 295 ALA   A CB  1 
ATOM   2228 N  N   . PRO   A 1 296 ? 24.57256 13.51675  35.54184  1.000 64.15867  ? 296 PRO   A N   1 
ATOM   2229 C  CA  . PRO   A 1 296 ? 25.71422 14.43217  35.42594  1.000 66.69071  ? 296 PRO   A CA  1 
ATOM   2230 C  C   . PRO   A 1 296 ? 26.69749 13.96942  34.36030  1.000 61.51757  ? 296 PRO   A C   1 
ATOM   2231 O  O   . PRO   A 1 296 ? 27.01322 12.78489  34.24543  1.000 55.87266  ? 296 PRO   A O   1 
ATOM   2232 C  CB  . PRO   A 1 296 ? 26.33960 14.39554  36.82326  1.000 71.34270  ? 296 PRO   A CB  1 
ATOM   2233 C  CG  . PRO   A 1 296 ? 25.20371 14.05652  37.72246  1.000 73.04874  ? 296 PRO   A CG  1 
ATOM   2234 C  CD  . PRO   A 1 296 ? 24.33027 13.11619  36.93880  1.000 69.28599  ? 296 PRO   A CD  1 
ATOM   2235 N  N   . VAL   A 1 297 ? 27.18159 14.92773  33.57324  1.000 61.05162  ? 297 VAL   A N   1 
ATOM   2236 C  CA  . VAL   A 1 297 ? 28.04489 14.61477  32.43993  1.000 56.63639  ? 297 VAL   A CA  1 
ATOM   2237 C  C   . VAL   A 1 297 ? 29.42577 14.22320  32.94175  1.000 58.06530  ? 297 VAL   A C   1 
ATOM   2238 O  O   . VAL   A 1 297 ? 30.03184 14.92550  33.76339  1.000 54.57388  ? 297 VAL   A O   1 
ATOM   2239 C  CB  . VAL   A 1 297 ? 28.12159 15.80699  31.47215  1.000 54.75030  ? 297 VAL   A CB  1 
ATOM   2240 C  CG1 . VAL   A 1 297 ? 29.03749 15.48360  30.30272  1.000 55.66219  ? 297 VAL   A CG1 1 
ATOM   2241 C  CG2 . VAL   A 1 297 ? 26.73216 16.17858  30.97754  1.000 60.42563  ? 297 VAL   A CG2 1 
ATOM   2242 N  N   . LEU   A 1 298 ? 29.93405 13.09642  32.44516  1.000 67.48476  ? 298 LEU   A N   1 
ATOM   2243 C  CA  . LEU   A 1 298 ? 31.28331 12.64388  32.75478  1.000 65.53984  ? 298 LEU   A CA  1 
ATOM   2244 C  C   . LEU   A 1 298 ? 32.28372 13.02716  31.67184  1.000 68.23196  ? 298 LEU   A C   1 
ATOM   2245 O  O   . LEU   A 1 298 ? 33.31583 13.63247  31.97431  1.000 66.25053  ? 298 LEU   A O   1 
ATOM   2246 C  CB  . LEU   A 1 298 ? 31.29893 11.12668  32.97324  1.000 61.38683  ? 298 LEU   A CB  1 
ATOM   2247 C  CG  . LEU   A 1 298 ? 30.46673 10.62226  34.15342  1.000 62.87302  ? 298 LEU   A CG  1 
ATOM   2248 C  CD1 . LEU   A 1 298 ? 30.68844 9.13476   34.37093  1.000 63.40750  ? 298 LEU   A CD1 1 
ATOM   2249 C  CD2 . LEU   A 1 298 ? 30.78744 11.40847  35.41626  1.000 66.07273  ? 298 LEU   A CD2 1 
ATOM   2250 N  N   . LYS   A 1 299 ? 32.00134 12.69433  30.41257  1.000 68.98990  ? 299 LYS   A N   1 
ATOM   2251 C  CA  . LYS   A 1 299 ? 32.88567 13.09970  29.32788  1.000 65.33261  ? 299 LYS   A CA  1 
ATOM   2252 C  C   . LYS   A 1 299 ? 32.09130 13.29110  28.04402  1.000 71.97751  ? 299 LYS   A C   1 
ATOM   2253 O  O   . LYS   A 1 299 ? 30.94246 12.85494  27.92103  1.000 76.52779  ? 299 LYS   A O   1 
ATOM   2254 C  CB  . LYS   A 1 299 ? 34.02158 12.09221  29.10447  1.000 62.44163  ? 299 LYS   A CB  1 
ATOM   2255 C  CG  . LYS   A 1 299 ? 35.33361 12.49718  29.76367  1.000 58.14455  ? 299 LYS   A CG  1 
ATOM   2256 C  CD  . LYS   A 1 299 ? 36.53365 11.91615  29.03343  1.000 59.23125  ? 299 LYS   A CD  1 
ATOM   2257 C  CE  . LYS   A 1 299 ? 37.83786 12.38582  29.65856  1.000 65.19840  ? 299 LYS   A CE  1 
ATOM   2258 N  NZ  . LYS   A 1 299 ? 39.02475 11.92325  28.88757  1.000 70.77605  ? 299 LYS   A NZ  1 
ATOM   2259 N  N   . MET   A 1 300 ? 32.72784 13.96434  27.08655  1.000 69.84424  ? 300 MET   A N   1 
ATOM   2260 C  CA  . MET   A 1 300 ? 32.12401 14.26329  25.79773  1.000 68.57583  ? 300 MET   A CA  1 
ATOM   2261 C  C   . MET   A 1 300 ? 33.16076 14.06965  24.69980  1.000 69.54955  ? 300 MET   A C   1 
ATOM   2262 O  O   . MET   A 1 300 ? 34.36916 14.06406  24.94817  1.000 67.51976  ? 300 MET   A O   1 
ATOM   2263 C  CB  . MET   A 1 300 ? 31.56396 15.69310  25.75176  1.000 64.75522  ? 300 MET   A CB  1 
ATOM   2264 C  CG  . MET   A 1 300 ? 30.45578 15.96594  26.75825  1.000 58.52870  ? 300 MET   A CG  1 
ATOM   2265 S  SD  . MET   A 1 300 ? 29.87314 17.67174  26.71617  1.000 63.52057  ? 300 MET   A SD  1 
ATOM   2266 C  CE  . MET   A 1 300 ? 31.37248 18.55433  27.13923  1.000 60.25617  ? 300 MET   A CE  1 
ATOM   2267 N  N   . GLU   A 1 301 ? 32.66643 13.90784  23.47480  1.000 70.52523  ? 301 GLU   A N   1 
ATOM   2268 C  CA  . GLU   A 1 301 ? 33.52836 13.70815  22.31301  1.000 65.19446  ? 301 GLU   A CA  1 
ATOM   2269 C  C   . GLU   A 1 301 ? 32.84435 14.30358  21.09293  1.000 61.18085  ? 301 GLU   A C   1 
ATOM   2270 O  O   . GLU   A 1 301 ? 31.72370 13.91129  20.75688  1.000 58.54102  ? 301 GLU   A O   1 
ATOM   2271 C  CB  . GLU   A 1 301 ? 33.82709 12.22180  22.09786  1.000 65.67455  ? 301 GLU   A CB  1 
ATOM   2272 C  CG  . GLU   A 1 301 ? 34.74412 11.92275  20.91828  1.000 73.24532  ? 301 GLU   A CG  1 
ATOM   2273 C  CD  . GLU   A 1 301 ? 36.20438 12.23330  21.20207  1.000 75.07840  ? 301 GLU   A CD  1 
ATOM   2274 O  OE1 . GLU   A 1 301 ? 36.51954 12.69191  22.32073  1.000 75.51876  ? 301 GLU   A OE1 1 
ATOM   2275 O  OE2 . GLU   A 1 301 ? 37.04164 12.01169  20.30208  1.000 79.93367  ? 301 GLU   A OE2 1 
ATOM   2276 N  N   . LEU   A 1 302 ? 33.51399 15.24273  20.43312  1.000 62.69998  ? 302 LEU   A N   1 
ATOM   2277 C  CA  . LEU   A 1 302 ? 32.92031 15.93501  19.30006  1.000 63.91942  ? 302 LEU   A CA  1 
ATOM   2278 C  C   . LEU   A 1 302 ? 33.10863 15.14995  18.00820  1.000 68.68383  ? 302 LEU   A C   1 
ATOM   2279 O  O   . LEU   A 1 302 ? 34.12699 14.48432  17.79862  1.000 71.23153  ? 302 LEU   A O   1 
ATOM   2280 C  CB  . LEU   A 1 302 ? 33.52818 17.32845  19.14259  1.000 61.59004  ? 302 LEU   A CB  1 
ATOM   2281 C  CG  . LEU   A 1 302 ? 32.86511 18.46093  19.92424  1.000 67.52594  ? 302 LEU   A CG  1 
ATOM   2282 C  CD1 . LEU   A 1 302 ? 33.67515 19.73686  19.78537  1.000 72.23011  ? 302 LEU   A CD1 1 
ATOM   2283 C  CD2 . LEU   A 1 302 ? 31.44160 18.67400  19.43674  1.000 67.41774  ? 302 LEU   A CD2 1 
ATOM   2284 N  N   . ASP   A 1 303 ? 32.10417 15.23482  17.13915  1.000 65.92469  ? 303 ASP   A N   1 
ATOM   2285 C  CA  . ASP   A 1 303 ? 32.22046 14.71602  15.78446  1.000 64.65503  ? 303 ASP   A CA  1 
ATOM   2286 C  C   . ASP   A 1 303 ? 32.90378 15.76211  14.91441  1.000 69.58068  ? 303 ASP   A C   1 
ATOM   2287 O  O   . ASP   A 1 303 ? 32.45580 16.91073  14.84307  1.000 77.76055  ? 303 ASP   A O   1 
ATOM   2288 C  CB  . ASP   A 1 303 ? 30.84201 14.36612  15.22246  1.000 66.65834  ? 303 ASP   A CB  1 
ATOM   2289 C  CG  . ASP   A 1 303 ? 30.91610 13.52852  13.95458  1.000 77.08527  ? 303 ASP   A CG  1 
ATOM   2290 O  OD1 . ASP   A 1 303 ? 31.92460 13.61837  13.22286  1.000 73.29431  ? 303 ASP   A OD1 1 
ATOM   2291 O  OD2 . ASP   A 1 303 ? 29.95575 12.77609  13.68747  1.000 86.29057  ? 303 ASP   A OD2 1 
ATOM   2292 N  N   . ARG   A 1 304 ? 33.99021 15.36564  14.25501  1.000 76.69805  ? 304 ARG   A N   1 
ATOM   2293 C  CA  . ARG   A 1 304 ? 34.78255 16.31493  13.48458  1.000 84.56148  ? 304 ARG   A CA  1 
ATOM   2294 C  C   . ARG   A 1 304 ? 34.63229 16.06855  11.98872  1.000 89.45513  ? 304 ARG   A C   1 
ATOM   2295 O  O   . ARG   A 1 304 ? 35.62584 16.02484  11.25585  1.000 89.86055  ? 304 ARG   A O   1 
ATOM   2296 C  CB  . ARG   A 1 304 ? 36.25227 16.23672  13.90292  1.000 85.95060  ? 304 ARG   A CB  1 
ATOM   2297 C  CG  . ARG   A 1 304 ? 36.44494 16.05188  15.40185  1.000 81.83128  ? 304 ARG   A CG  1 
ATOM   2298 C  CD  . ARG   A 1 304 ? 37.88276 16.29815  15.82648  1.000 86.69920  ? 304 ARG   A CD  1 
ATOM   2299 N  NE  . ARG   A 1 304 ? 38.16415 17.71785  16.00291  1.000 96.05659  ? 304 ARG   A NE  1 
ATOM   2300 C  CZ  . ARG   A 1 304 ? 37.98892 18.37912  17.13922  1.000 92.95385  ? 304 ARG   A CZ  1 
ATOM   2301 N  NH1 . ARG   A 1 304 ? 37.52885 17.77849  18.22493  1.000 83.07150  ? 304 ARG   A NH1 1 
ATOM   2302 N  NH2 . ARG   A 1 304 ? 38.28244 19.67546  17.18770  1.000 86.29139  ? 304 ARG   A NH2 1 
ATOM   2303 N  N   . SER   A 1 305 ? 33.39355 15.90683  11.52941  1.000 87.04385  ? 305 SER   A N   1 
ATOM   2304 C  CA  . SER   A 1 305 ? 33.10014 15.74718  10.11202  1.000 86.74958  ? 305 SER   A CA  1 
ATOM   2305 C  C   . SER   A 1 305 ? 32.92649 17.07874  9.39356   1.000 100.28719 ? 305 SER   A C   1 
ATOM   2306 O  O   . SER   A 1 305 ? 32.70157 17.08639  8.17866   1.000 111.91891 ? 305 SER   A O   1 
ATOM   2307 C  CB  . SER   A 1 305 ? 31.84181 14.89216  9.92622   1.000 78.60758  ? 305 SER   A CB  1 
ATOM   2308 O  OG  . SER   A 1 305 ? 32.02003 13.59666  10.47206  1.000 74.90305  ? 305 SER   A OG  1 
ATOM   2309 N  N   . ALA   A 1 306 ? 33.02472 18.19496  10.11114  1.000 98.29943  ? 306 ALA   A N   1 
ATOM   2310 C  CA  . ALA   A 1 306 ? 32.90870 19.52723  9.53464   1.000 102.77225 ? 306 ALA   A CA  1 
ATOM   2311 C  C   . ALA   A 1 306 ? 33.43131 20.53358  10.54688  1.000 101.53336 ? 306 ALA   A C   1 
ATOM   2312 O  O   . ALA   A 1 306 ? 33.39833 20.28264  11.75561  1.000 94.18268  ? 306 ALA   A O   1 
ATOM   2313 C  CB  . ALA   A 1 306 ? 31.45914 19.85720  9.15526   1.000 99.60819  ? 306 ALA   A CB  1 
ATOM   2314 N  N   . ASP   A 1 307 ? 33.92146 21.66696  10.04217  1.000 107.59350 ? 307 ASP   A N   1 
ATOM   2315 C  CA  . ASP   A 1 307 ? 34.35543 22.73437  10.93963  1.000 110.95988 ? 307 ASP   A CA  1 
ATOM   2316 C  C   . ASP   A 1 307 ? 33.23122 23.20767  11.85477  1.000 105.32504 ? 307 ASP   A C   1 
ATOM   2317 O  O   . ASP   A 1 307 ? 33.51648 23.51047  13.02679  1.000 98.82111  ? 307 ASP   A O   1 
ATOM   2318 C  CB  . ASP   A 1 307 ? 34.94915 23.89526  10.12956  1.000 106.79158 ? 307 ASP   A CB  1 
ATOM   2319 C  CG  . ASP   A 1 307 ? 35.76733 24.84654  10.98493  1.000 99.38215  ? 307 ASP   A CG  1 
ATOM   2320 O  OD1 . ASP   A 1 307 ? 35.98377 24.54631  12.17817  1.000 84.21059  ? 307 ASP   A OD1 1 
ATOM   2321 O  OD2 . ASP   A 1 307 ? 36.19692 25.89591  10.46218  1.000 109.39788 ? 307 ASP   A OD2 1 
ATOM   2322 N  N   . PRO   A 1 308 ? 31.97813 23.31114  11.41410  1.000 98.58656  ? 308 PRO   A N   1 
ATOM   2323 C  CA  . PRO   A 1 308 ? 30.86588 23.31528  12.36698  1.000 92.77471  ? 308 PRO   A CA  1 
ATOM   2324 C  C   . PRO   A 1 308 ? 30.50719 21.89349  12.75934  1.000 96.82057  ? 308 PRO   A C   1 
ATOM   2325 O  O   . PRO   A 1 308 ? 29.94649 21.14069  11.94787  1.000 93.70547  ? 308 PRO   A O   1 
ATOM   2326 C  CB  . PRO   A 1 308 ? 29.72890 23.98875  11.58480  1.000 84.03113  ? 308 PRO   A CB  1 
ATOM   2327 C  CG  . PRO   A 1 308 ? 30.03477 23.69742  10.16372  1.000 88.01704  ? 308 PRO   A CG  1 
ATOM   2328 C  CD  . PRO   A 1 308 ? 31.53295 23.67447  10.05394  1.000 94.06879  ? 308 PRO   A CD  1 
ATOM   2329 N  N   . PRO   A 1 309 ? 30.82837 21.48321  13.98448  1.000 91.46098  ? 309 PRO   A N   1 
ATOM   2330 C  CA  . PRO   A 1 309 ? 30.64933 20.07774  14.37873  1.000 79.76754  ? 309 PRO   A CA  1 
ATOM   2331 C  C   . PRO   A 1 309 ? 29.19584 19.65511  14.27516  1.000 83.87307  ? 309 PRO   A C   1 
ATOM   2332 O  O   . PRO   A 1 309 ? 28.29965 20.34103  14.78986  1.000 88.13456  ? 309 PRO   A O   1 
ATOM   2333 C  CB  . PRO   A 1 309 ? 31.13440 20.05567  15.83632  1.000 70.82744  ? 309 PRO   A CB  1 
ATOM   2334 C  CG  . PRO   A 1 309 ? 32.04041 21.23860  15.94988  1.000 70.84175  ? 309 PRO   A CG  1 
ATOM   2335 C  CD  . PRO   A 1 309 ? 31.43348 22.28295  15.06230  1.000 87.27567  ? 309 PRO   A CD  1 
ATOM   2336 N  N   . PRO   A 1 310 ? 28.92085 18.52644  13.61456  1.000 79.05008  ? 310 PRO   A N   1 
ATOM   2337 C  CA  . PRO   A 1 310 ? 27.51694 18.12433  13.43326  1.000 80.27503  ? 310 PRO   A CA  1 
ATOM   2338 C  C   . PRO   A 1 310 ? 26.86484 17.62049  14.70711  1.000 78.96554  ? 310 PRO   A C   1 
ATOM   2339 O  O   . PRO   A 1 310 ? 25.71112 17.97089  14.98388  1.000 77.90914  ? 310 PRO   A O   1 
ATOM   2340 C  CB  . PRO   A 1 310 ? 27.60854 17.02775  12.36359  1.000 78.59279  ? 310 PRO   A CB  1 
ATOM   2341 C  CG  . PRO   A 1 310 ? 28.97447 16.45151  12.54251  1.000 74.30862  ? 310 PRO   A CG  1 
ATOM   2342 C  CD  . PRO   A 1 310 ? 29.85787 17.59787  12.95785  1.000 74.62387  ? 310 PRO   A CD  1 
ATOM   2343 N  N   . ALA   A 1 311 ? 27.56399 16.80619  15.49310  1.000 77.48508  ? 311 ALA   A N   1 
ATOM   2344 C  CA  . ALA   A 1 311 ? 26.97899 16.22966  16.69306  1.000 70.18378  ? 311 ALA   A CA  1 
ATOM   2345 C  C   . ALA   A 1 311 ? 28.06730 16.03045  17.73583  1.000 65.71212  ? 311 ALA   A C   1 
ATOM   2346 O  O   . ALA   A 1 311 ? 29.25942 16.19599  17.46539  1.000 66.30499  ? 311 ALA   A O   1 
ATOM   2347 C  CB  . ALA   A 1 311 ? 26.27031 14.90545  16.38943  1.000 69.27076  ? 311 ALA   A CB  1 
ATOM   2348 N  N   . ILE   A 1 312 ? 27.63874 15.66870  18.94064  1.000 67.80189  ? 312 ILE   A N   1 
ATOM   2349 C  CA  . ILE   A 1 312 ? 28.55430 15.40328  20.04289  1.000 66.38429  ? 312 ILE   A CA  1 
ATOM   2350 C  C   . ILE   A 1 312 ? 28.02677 14.22009  20.84462  1.000 68.95739  ? 312 ILE   A C   1 
ATOM   2351 O  O   . ILE   A 1 312 ? 26.81980 14.10296  21.08774  1.000 69.10094  ? 312 ILE   A O   1 
ATOM   2352 C  CB  . ILE   A 1 312 ? 28.75293 16.65480  20.92928  1.000 63.23576  ? 312 ILE   A CB  1 
ATOM   2353 C  CG1 . ILE   A 1 312 ? 29.75964 16.38038  22.05065  1.000 62.79350  ? 312 ILE   A CG1 1 
ATOM   2354 C  CG2 . ILE   A 1 312 ? 27.42460 17.15661  21.48224  1.000 65.69404  ? 312 ILE   A CG2 1 
ATOM   2355 C  CD1 . ILE   A 1 312 ? 30.09397 17.60508  22.88307  1.000 59.81010  ? 312 ILE   A CD1 1 
ATOM   2356 N  N   . TRP   A 1 313 ? 28.93602 13.32418  21.22417  1.000 68.08386  ? 313 TRP   A N   1 
ATOM   2357 C  CA  . TRP   A 1 313 ? 28.61287 12.17947  22.06011  1.000 65.60934  ? 313 TRP   A CA  1 
ATOM   2358 C  C   . TRP   A 1 313 ? 28.87474 12.51534  23.52048  1.000 60.76930  ? 313 TRP   A C   1 
ATOM   2359 O  O   . TRP   A 1 313 ? 29.90568 13.10151  23.86177  1.000 58.57531  ? 313 TRP   A O   1 
ATOM   2360 C  CB  . TRP   A 1 313 ? 29.43844 10.95795  21.65288  1.000 65.84956  ? 313 TRP   A CB  1 
ATOM   2361 C  CG  . TRP   A 1 313 ? 28.97269 10.30279  20.39199  1.000 63.05114  ? 313 TRP   A CG  1 
ATOM   2362 C  CD1 . TRP   A 1 313 ? 29.39447 10.57212  19.12313  1.000 56.97518  ? 313 TRP   A CD1 1 
ATOM   2363 C  CD2 . TRP   A 1 313 ? 27.99649 9.26004   20.27818  1.000 70.79137  ? 313 TRP   A CD2 1 
ATOM   2364 N  NE1 . TRP   A 1 313 ? 28.73973 9.76360   18.22559  1.000 65.26358  ? 313 TRP   A NE1 1 
ATOM   2365 C  CE2 . TRP   A 1 313 ? 27.87737 8.94760   18.90977  1.000 72.40495  ? 313 TRP   A CE2 1 
ATOM   2366 C  CE3 . TRP   A 1 313 ? 27.21235 8.55996   21.20087  1.000 73.36518  ? 313 TRP   A CE3 1 
ATOM   2367 C  CZ2 . TRP   A 1 313 ? 27.00323 7.96821   18.44082  1.000 80.70994  ? 313 TRP   A CZ2 1 
ATOM   2368 C  CZ3 . TRP   A 1 313 ? 26.34543 7.58784   20.73363  1.000 74.03424  ? 313 TRP   A CZ3 1 
ATOM   2369 C  CH2 . TRP   A 1 313 ? 26.24805 7.30123   19.36631  1.000 79.48705  ? 313 TRP   A CH2 1 
ATOM   2370 N  N   . VAL   A 1 314 ? 27.93408 12.13151  24.37672  1.000 58.41848  ? 314 VAL   A N   1 
ATOM   2371 C  CA  . VAL   A 1 314 ? 27.98120 12.41145  25.80454  1.000 52.83144  ? 314 VAL   A CA  1 
ATOM   2372 C  C   . VAL   A 1 314 ? 27.89903 11.09133  26.55542  1.000 57.76117  ? 314 VAL   A C   1 
ATOM   2373 O  O   . VAL   A 1 314 ? 27.00402 10.27383  26.29297  1.000 65.28706  ? 314 VAL   A O   1 
ATOM   2374 C  CB  . VAL   A 1 314 ? 26.84258 13.35465  26.23320  1.000 57.82146  ? 314 VAL   A CB  1 
ATOM   2375 C  CG1 . VAL   A 1 314 ? 26.87330 13.57892  27.73613  1.000 69.61221  ? 314 VAL   A CG1 1 
ATOM   2376 C  CG2 . VAL   A 1 314 ? 26.94226 14.67469  25.48730  1.000 63.68846  ? 314 VAL   A CG2 1 
ATOM   2377 N  N   . ALA   A 1 315 ? 28.83853 10.88428  27.47883  1.000 56.14838  ? 315 ALA   A N   1 
ATOM   2378 C  CA  . ALA   A 1 315 ? 28.84166 9.74277   28.38270  1.000 64.03450  ? 315 ALA   A CA  1 
ATOM   2379 C  C   . ALA   A 1 315 ? 28.71861 10.26887  29.80451  1.000 63.66826  ? 315 ALA   A C   1 
ATOM   2380 O  O   . ALA   A 1 315 ? 29.55440 11.06545  30.25030  1.000 59.91696  ? 315 ALA   A O   1 
ATOM   2381 C  CB  . ALA   A 1 315 ? 30.11390 8.90945   28.22013  1.000 65.64625  ? 315 ALA   A CB  1 
ATOM   2382 N  N   . THR   A 1 316 ? 27.67679 9.82987   30.50556  1.000 66.27845  ? 316 THR   A N   1 
ATOM   2383 C  CA  . THR   A 1 316 ? 27.35604 10.26650  31.85433  1.000 61.64840  ? 316 THR   A CA  1 
ATOM   2384 C  C   . THR   A 1 316 ? 27.53109 9.10731   32.83442  1.000 62.12283  ? 316 THR   A C   1 
ATOM   2385 O  O   . THR   A 1 316 ? 28.10001 8.06171   32.50116  1.000 63.45935  ? 316 THR   A O   1 
ATOM   2386 C  CB  . THR   A 1 316 ? 25.93098 10.82309  31.89554  1.000 58.22327  ? 316 THR   A CB  1 
ATOM   2387 O  OG1 . THR   A 1 316 ? 25.01069 9.80271   31.48780  1.000 59.06361  ? 316 THR   A OG1 1 
ATOM   2388 C  CG2 . THR   A 1 316 ? 25.79751 12.01671  30.96301  1.000 60.49506  ? 316 THR   A CG2 1 
ATOM   2389 N  N   . THR   A 1 317 ? 27.03343 9.29832   34.05969  1.000 62.45473  ? 317 THR   A N   1 
ATOM   2390 C  CA  . THR   A 1 317 ? 27.07613 8.23467   35.05595  1.000 62.52005  ? 317 THR   A CA  1 
ATOM   2391 C  C   . THR   A 1 317 ? 26.14349 7.08349   34.70402  1.000 65.11450  ? 317 THR   A C   1 
ATOM   2392 O  O   . THR   A 1 317 ? 26.38492 5.95102   35.13698  1.000 73.56850  ? 317 THR   A O   1 
ATOM   2393 C  CB  . THR   A 1 317 ? 26.71643 8.77875   36.43979  1.000 60.41406  ? 317 THR   A CB  1 
ATOM   2394 O  OG1 . THR   A 1 317 ? 25.37128 9.26808   36.42746  1.000 65.57439  ? 317 THR   A OG1 1 
ATOM   2395 C  CG2 . THR   A 1 317 ? 27.65958 9.90506   36.83882  1.000 59.17088  ? 317 THR   A CG2 1 
ATOM   2396 N  N   . LYS   A 1 318 ? 25.08426 7.34564   33.94158  1.000 64.71270  ? 318 LYS   A N   1 
ATOM   2397 C  CA  . LYS   A 1 318 ? 24.21003 6.27503   33.49230  1.000 70.08469  ? 318 LYS   A CA  1 
ATOM   2398 C  C   . LYS   A 1 318 ? 24.92740 5.39332   32.47363  1.000 68.39327  ? 318 LYS   A C   1 
ATOM   2399 O  O   . LYS   A 1 318 ? 25.93766 5.77684   31.87618  1.000 66.48416  ? 318 LYS   A O   1 
ATOM   2400 C  CB  . LYS   A 1 318 ? 22.92429 6.84255   32.88981  1.000 68.94115  ? 318 LYS   A CB  1 
ATOM   2401 C  CG  . LYS   A 1 318 ? 21.96399 7.43200   33.91332  1.000 66.63908  ? 318 LYS   A CG  1 
ATOM   2402 C  CD  . LYS   A 1 318 ? 20.75142 8.05567   33.24158  1.000 72.00707  ? 318 LYS   A CD  1 
ATOM   2403 C  CE  . LYS   A 1 318 ? 19.71299 8.47824   34.26707  1.000 69.70508  ? 318 LYS   A CE  1 
ATOM   2404 N  NZ  . LYS   A 1 318 ? 19.14411 7.30588   34.99099  1.000 77.63803  ? 318 LYS   A NZ  1 
ATOM   2405 N  N   . SER   A 1 319 ? 24.38296 4.18976   32.28265  1.000 65.26325  ? 319 SER   A N   1 
ATOM   2406 C  CA  . SER   A 1 319 ? 24.98777 3.20200   31.39767  1.000 71.62702  ? 319 SER   A CA  1 
ATOM   2407 C  C   . SER   A 1 319 ? 24.81308 3.53711   29.92198  1.000 72.87004  ? 319 SER   A C   1 
ATOM   2408 O  O   . SER   A 1 319 ? 25.61416 3.07914   29.09910  1.000 73.58268  ? 319 SER   A O   1 
ATOM   2409 C  CB  . SER   A 1 319 ? 24.39662 1.81580   31.67107  1.000 73.44579  ? 319 SER   A CB  1 
ATOM   2410 O  OG  . SER   A 1 319 ? 24.61345 1.41371   33.01708  1.000 73.14784  ? 319 SER   A OG  1 
ATOM   2411 N  N   . THR   A 1 320 ? 23.79134 4.31047   29.56506  1.000 63.92995  ? 320 THR   A N   1 
ATOM   2412 C  CA  . THR   A 1 320 ? 23.56282 4.65015   28.16883  1.000 61.15969  ? 320 THR   A CA  1 
ATOM   2413 C  C   . THR   A 1 320 ? 24.41123 5.84911   27.75760  1.000 65.55642  ? 320 THR   A C   1 
ATOM   2414 O  O   . THR   A 1 320 ? 24.72213 6.72647   28.56823  1.000 66.70890  ? 320 THR   A O   1 
ATOM   2415 C  CB  . THR   A 1 320 ? 22.08345 4.94542   27.92011  1.000 64.62703  ? 320 THR   A CB  1 
ATOM   2416 O  OG1 . THR   A 1 320 ? 21.90583 5.38040   26.56791  1.000 73.30311  ? 320 THR   A OG1 1 
ATOM   2417 C  CG2 . THR   A 1 320 ? 21.58526 6.03246   28.86737  1.000 75.83055  ? 320 THR   A CG2 1 
ATOM   2418 N  N   . VAL   A 1 321 ? 24.79915 5.86875   26.48372  1.000 62.03984  ? 321 VAL   A N   1 
ATOM   2419 C  CA  . VAL   A 1 321 ? 25.60239 6.94179   25.90595  1.000 69.12666  ? 321 VAL   A CA  1 
ATOM   2420 C  C   . VAL   A 1 321 ? 24.77611 7.61534   24.82008  1.000 71.81246  ? 321 VAL   A C   1 
ATOM   2421 O  O   . VAL   A 1 321 ? 24.13670 6.93405   24.01072  1.000 73.39305  ? 321 VAL   A O   1 
ATOM   2422 C  CB  . VAL   A 1 321 ? 26.93095 6.41021   25.33701  1.000 69.66163  ? 321 VAL   A CB  1 
ATOM   2423 C  CG1 . VAL   A 1 321 ? 27.72080 7.52751   24.68173  1.000 71.48606  ? 321 VAL   A CG1 1 
ATOM   2424 C  CG2 . VAL   A 1 321 ? 27.74565 5.74649   26.43828  1.000 66.38241  ? 321 VAL   A CG2 1 
ATOM   2425 N  N   . ASN   A 1 322 ? 24.78253 8.94486   24.79505  1.000 64.83345  ? 322 ASN   A N   1 
ATOM   2426 C  CA  . ASN   A 1 322 ? 23.90327 9.65779   23.87974  1.000 60.64609  ? 322 ASN   A CA  1 
ATOM   2427 C  C   . ASN   A 1 322 ? 24.69530 10.39812  22.80927  1.000 65.81488  ? 322 ASN   A C   1 
ATOM   2428 O  O   . ASN   A 1 322 ? 25.86687 10.72846  22.98757  1.000 68.99516  ? 322 ASN   A O   1 
ATOM   2429 C  CB  . ASN   A 1 322 ? 23.00386 10.63450  24.64348  1.000 59.11576  ? 322 ASN   A CB  1 
ATOM   2430 C  CG  . ASN   A 1 322 ? 21.96425 9.92460   25.48708  1.000 58.02612  ? 322 ASN   A CG  1 
ATOM   2431 O  OD1 . ASN   A 1 322 ? 21.58741 8.78806   25.20019  1.000 54.13648  ? 322 ASN   A OD1 1 
ATOM   2432 N  ND2 . ASN   A 1 322 ? 21.49141 10.59343  26.53205  1.000 59.81180  ? 322 ASN   A ND2 1 
ATOM   2433 N  N   . LYS   A 1 323 ? 24.03304 10.65368  21.68223  1.000 69.41941  ? 323 LYS   A N   1 
ATOM   2434 C  CA  . LYS   A 1 323 ? 24.58899 11.44695  20.59119  1.000 72.07879  ? 323 LYS   A CA  1 
ATOM   2435 C  C   . LYS   A 1 323 ? 23.59287 12.54438  20.25677  1.000 75.02210  ? 323 LYS   A C   1 
ATOM   2436 O  O   . LYS   A 1 323 ? 22.51612 12.26265  19.71166  1.000 79.73674  ? 323 LYS   A O   1 
ATOM   2437 C  CB  . LYS   A 1 323 ? 24.87485 10.60124  19.35329  1.000 74.57844  ? 323 LYS   A CB  1 
ATOM   2438 C  CG  . LYS   A 1 323 ? 25.60153 11.38982  18.27236  1.000 77.34264  ? 323 LYS   A CG  1 
ATOM   2439 C  CD  . LYS   A 1 323 ? 25.37687 10.81746  16.88648  1.000 79.39358  ? 323 LYS   A CD  1 
ATOM   2440 C  CE  . LYS   A 1 323 ? 24.00161 11.17993  16.35735  1.000 79.27984  ? 323 LYS   A CE  1 
ATOM   2441 N  NZ  . LYS   A 1 323 ? 23.80152 10.67695  14.97120  1.000 86.10098  ? 323 LYS   A NZ  1 
ATOM   2442 N  N   . TRP   A 1 324 ? 23.96472 13.78370  20.57332  1.000 71.78643  ? 324 TRP   A N   1 
ATOM   2443 C  CA  . TRP   A 1 324 ? 23.11897 14.95212  20.38032  1.000 74.35184  ? 324 TRP   A CA  1 
ATOM   2444 C  C   . TRP   A 1 324 ? 23.58302 15.72062  19.15259  1.000 76.99820  ? 324 TRP   A C   1 
ATOM   2445 O  O   . TRP   A 1 324 ? 24.75980 16.08072  19.05132  1.000 75.33238  ? 324 TRP   A O   1 
ATOM   2446 C  CB  . TRP   A 1 324 ? 23.17173 15.86608  21.60347  1.000 70.64168  ? 324 TRP   A CB  1 
ATOM   2447 C  CG  . TRP   A 1 324 ? 22.94536 15.17790  22.89847  1.000 71.35976  ? 324 TRP   A CG  1 
ATOM   2448 C  CD1 . TRP   A 1 324 ? 23.86559 14.50111  23.64284  1.000 70.39233  ? 324 TRP   A CD1 1 
ATOM   2449 C  CD2 . TRP   A 1 324 ? 21.71714 15.11624  23.62149  1.000 73.28122  ? 324 TRP   A CD2 1 
ATOM   2450 N  NE1 . TRP   A 1 324 ? 23.28051 14.01410  24.78629  1.000 70.13082  ? 324 TRP   A NE1 1 
ATOM   2451 C  CE2 . TRP   A 1 324 ? 21.95997 14.38007  24.79634  1.000 69.08359  ? 324 TRP   A CE2 1 
ATOM   2452 C  CE3 . TRP   A 1 324 ? 20.43293 15.61311  23.38867  1.000 75.44899  ? 324 TRP   A CE3 1 
ATOM   2453 C  CZ2 . TRP   A 1 324 ? 20.96443 14.12694  25.73413  1.000 66.43466  ? 324 TRP   A CZ2 1 
ATOM   2454 C  CZ3 . TRP   A 1 324 ? 19.44793 15.36205  24.31688  1.000 73.94525  ? 324 TRP   A CZ3 1 
ATOM   2455 C  CH2 . TRP   A 1 324 ? 19.71702 14.62552  25.47691  1.000 68.31062  ? 324 TRP   A CH2 1 
ATOM   2456 N  N   . THR   A 1 325 ? 22.65817 15.98269  18.23621  1.000 75.01715  ? 325 THR   A N   1 
ATOM   2457 C  CA  . THR   A 1 325 ? 22.97554 16.72531  17.02867  1.000 75.36610  ? 325 THR   A CA  1 
ATOM   2458 C  C   . THR   A 1 325 ? 23.11375 18.21649  17.33372  1.000 76.37725  ? 325 THR   A C   1 
ATOM   2459 O  O   . THR   A 1 325 ? 22.61302 18.72281  18.34114  1.000 78.65260  ? 325 THR   A O   1 
ATOM   2460 C  CB  . THR   A 1 325 ? 21.89770 16.49989  15.96807  1.000 79.35556  ? 325 THR   A CB  1 
ATOM   2461 O  OG1 . THR   A 1 325 ? 22.15246 17.33554  14.83276  1.000 92.88227  ? 325 THR   A OG1 1 
ATOM   2462 C  CG2 . THR   A 1 325 ? 20.52429 16.81917  16.53200  1.000 74.31897  ? 325 THR   A CG2 1 
ATOM   2463 N  N   . LEU   A 1 326 ? 23.80805 18.92254  16.44314  1.000 75.56017  ? 326 LEU   A N   1 
ATOM   2464 C  CA  . LEU   A 1 326 ? 24.06405 20.35800  16.58303  1.000 84.35139  ? 326 LEU   A CA  1 
ATOM   2465 C  C   . LEU   A 1 326 ? 23.55399 21.05904  15.32744  1.000 92.95320  ? 326 LEU   A C   1 
ATOM   2466 O  O   . LEU   A 1 326 ? 24.32709 21.38879  14.42523  1.000 97.73340  ? 326 LEU   A O   1 
ATOM   2467 C  CB  . LEU   A 1 326 ? 25.56249 20.63020  16.81666  1.000 83.47426  ? 326 LEU   A CB  1 
ATOM   2468 C  CG  . LEU   A 1 326 ? 26.20966 19.91765  18.00509  1.000 79.04348  ? 326 LEU   A CG  1 
ATOM   2469 C  CD1 . LEU   A 1 326 ? 27.71038 20.15568  18.01850  1.000 72.10256  ? 326 LEU   A CD1 1 
ATOM   2470 C  CD2 . LEU   A 1 326 ? 25.58189 20.37436  19.31186  1.000 77.84306  ? 326 LEU   A CD2 1 
ATOM   2471 N  N   . LYS   A 1 327 ? 22.24208 21.29405  15.27623  1.000 94.58968  ? 327 LYS   A N   1 
ATOM   2472 C  CA  . LYS   A 1 327 ? 21.58960 21.90554  14.11655  1.000 100.30707 ? 327 LYS   A CA  1 
ATOM   2473 C  C   . LYS   A 1 327 ? 20.75589 23.09409  14.58623  1.000 101.23655 ? 327 LYS   A C   1 
ATOM   2474 O  O   . LYS   A 1 327 ? 19.60192 22.93598  14.99382  1.000 95.99477  ? 327 LYS   A O   1 
ATOM   2475 C  CB  . LYS   A 1 327 ? 20.73788 20.88443  13.36731  1.000 95.00012  ? 327 LYS   A CB  1 
ATOM   2476 C  CG  . LYS   A 1 327 ? 21.52828 19.70259  12.84119  1.000 88.71889  ? 327 LYS   A CG  1 
ATOM   2477 C  CD  . LYS   A 1 327 ? 22.65081 20.15787  11.92409  1.000 84.81751  ? 327 LYS   A CD  1 
ATOM   2478 C  CE  . LYS   A 1 327 ? 23.72669 19.09159  11.79711  1.000 81.69081  ? 327 LYS   A CE  1 
ATOM   2479 N  NZ  . LYS   A 1 327 ? 23.16793 17.77958  11.37140  1.000 83.60183  ? 327 LYS   A NZ  1 
ATOM   2480 N  N   . GLY   A 1 328 ? 21.34492 24.28399  14.52346  1.000 110.46486 ? 328 GLY   A N   1 
ATOM   2481 C  CA  . GLY   A 1 328 ? 20.63649 25.51760  14.77870  1.000 116.30828 ? 328 GLY   A CA  1 
ATOM   2482 C  C   . GLY   A 1 328 ? 20.09311 26.19576  13.54420  1.000 123.98803 ? 328 GLY   A C   1 
ATOM   2483 O  O   . GLY   A 1 328 ? 19.54218 27.29728  13.63848  1.000 113.33466 ? 328 GLY   A O   1 
ATOM   2484 N  N   . ILE   A 1 329 ? 20.23324 25.56754  12.38094  1.000 128.16596 ? 329 ILE   A N   1 
ATOM   2485 C  CA  . ILE   A 1 329 ? 19.75303 26.13482  11.12908  1.000 117.19824 ? 329 ILE   A CA  1 
ATOM   2486 C  C   . ILE   A 1 329 ? 19.13088 25.04183  10.26795  1.000 110.62307 ? 329 ILE   A C   1 
ATOM   2487 O  O   . ILE   A 1 329 ? 19.41990 23.85768  10.44578  1.000 107.25905 ? 329 ILE   A O   1 
ATOM   2488 C  CB  . ILE   A 1 329 ? 20.88547 26.84910  10.37146  1.000 115.94340 ? 329 ILE   A CB  1 
ATOM   2489 C  CG1 . ILE   A 1 329 ? 20.34280 27.51817  9.10696   1.000 109.91517 ? 329 ILE   A CG1 1 
ATOM   2490 C  CG2 . ILE   A 1 329 ? 21.99868 25.86900  10.02828  1.000 111.54474 ? 329 ILE   A CG2 1 
ATOM   2491 C  CD1 . ILE   A 1 329 ? 19.31446 28.59369  9.38079   1.000 100.49075 ? 329 ILE   A CD1 1 
ATOM   2492 N  N   . THR   A 1 343 ? 16.74445 27.85960  19.90483  1.000 96.58162  ? 343 THR   A N   1 
ATOM   2493 C  CA  . THR   A 1 343 ? 15.97773 28.93567  19.28825  1.000 105.12538 ? 343 THR   A CA  1 
ATOM   2494 C  C   . THR   A 1 343 ? 16.46221 30.30522  19.75897  1.000 111.57259 ? 343 THR   A C   1 
ATOM   2495 O  O   . THR   A 1 343 ? 17.29340 30.93157  19.10155  1.000 104.79145 ? 343 THR   A O   1 
ATOM   2496 C  CB  . THR   A 1 343 ? 14.47363 28.79857  19.58589  1.000 106.42691 ? 343 THR   A CB  1 
ATOM   2497 O  OG1 . THR   A 1 343 ? 14.27083 28.69827  21.00065  1.000 113.59860 ? 343 THR   A OG1 1 
ATOM   2498 C  CG2 . THR   A 1 343 ? 13.90654 27.56147  18.90422  1.000 93.65390  ? 343 THR   A CG2 1 
ATOM   2499 N  N   . ASN   A 1 344 ? 15.94230 30.77357  20.89684  1.000 116.85859 ? 344 ASN   A N   1 
ATOM   2500 C  CA  . ASN   A 1 344 ? 16.32054 32.09716  21.38103  1.000 112.38047 ? 344 ASN   A CA  1 
ATOM   2501 C  C   . ASN   A 1 344 ? 16.66797 32.09544  22.86998  1.000 114.07705 ? 344 ASN   A C   1 
ATOM   2502 O  O   . ASN   A 1 344 ? 17.82321 32.36499  23.22120  1.000 109.12119 ? 344 ASN   A O   1 
ATOM   2503 C  CB  . ASN   A 1 344 ? 15.20965 33.11601  21.09941  1.000 105.07918 ? 344 ASN   A CB  1 
ATOM   2504 C  CG  . ASN   A 1 344 ? 14.51023 32.86933  19.77870  1.000 106.96972 ? 344 ASN   A CG  1 
ATOM   2505 O  OD1 . ASN   A 1 344 ? 13.47060 32.21151  19.72841  1.000 113.41372 ? 344 ASN   A OD1 1 
ATOM   2506 N  ND2 . ASN   A 1 344 ? 15.07823 33.39489  18.69996  1.000 100.80301 ? 344 ASN   A ND2 1 
ATOM   2507 N  N   . PRO   A 1 345 ? 15.72021 31.79688  23.78650  1.000 115.33248 ? 345 PRO   A N   1 
ATOM   2508 C  CA  . PRO   A 1 345 ? 15.98314 32.07433  25.20450  1.000 100.96586 ? 345 PRO   A CA  1 
ATOM   2509 C  C   . PRO   A 1 345 ? 16.76611 30.97299  25.90134  1.000 97.47590  ? 345 PRO   A C   1 
ATOM   2510 O  O   . PRO   A 1 345 ? 17.95611 30.77424  25.63698  1.000 94.49373  ? 345 PRO   A O   1 
ATOM   2511 C  CB  . PRO   A 1 345 ? 14.57288 32.21336  25.79930  1.000 94.18859  ? 345 PRO   A CB  1 
ATOM   2512 C  CG  . PRO   A 1 345 ? 13.60986 31.68636  24.72414  1.000 101.86445 ? 345 PRO   A CG  1 
ATOM   2513 C  CD  . PRO   A 1 345 ? 14.44505 31.07730  23.63829  1.000 110.13315 ? 345 PRO   A CD  1 
ATOM   2514 N  N   . ILE   A 1 346 ? 16.09979 30.26040  26.80429  1.000 95.89508  ? 346 ILE   A N   1 
ATOM   2515 C  CA  . ILE   A 1 346 ? 16.72496 29.20544  27.58870  1.000 92.21855  ? 346 ILE   A CA  1 
ATOM   2516 C  C   . ILE   A 1 346 ? 16.41587 27.82241  27.00490  1.000 93.19973  ? 346 ILE   A C   1 
ATOM   2517 O  O   . ILE   A 1 346 ? 16.61013 26.80506  27.67104  1.000 86.03402  ? 346 ILE   A O   1 
ATOM   2518 C  CB  . ILE   A 1 346 ? 16.31700 29.30537  29.06979  1.000 81.95570  ? 346 ILE   A CB  1 
ATOM   2519 C  CG1 . ILE   A 1 346 ? 17.31791 28.57965  29.97698  1.000 76.01928  ? 346 ILE   A CG1 1 
ATOM   2520 C  CG2 . ILE   A 1 346 ? 14.88523 28.80966  29.28048  1.000 85.35928  ? 346 ILE   A CG2 1 
ATOM   2521 C  CD1 . ILE   A 1 346 ? 18.71433 29.15851  29.93032  1.000 76.35645  ? 346 ILE   A CD1 1 
ATOM   2522 N  N   . THR   A 1 347 ? 15.96060 27.77147  25.75981  1.000 96.80791  ? 347 THR   A N   1 
ATOM   2523 C  CA  . THR   A 1 347 ? 15.54896 26.50728  25.16169  1.000 92.07435  ? 347 THR   A CA  1 
ATOM   2524 C  C   . THR   A 1 347 ? 16.75276 25.59621  24.95032  1.000 80.97048  ? 347 THR   A C   1 
ATOM   2525 O  O   . THR   A 1 347 ? 17.74474 26.01769  24.34296  1.000 81.47145  ? 347 THR   A O   1 
ATOM   2526 C  CB  . THR   A 1 347 ? 14.84725 26.75054  23.82763  1.000 98.70080  ? 347 THR   A CB  1 
ATOM   2527 O  OG1 . THR   A 1 347 ? 15.73242 27.44646  22.93995  1.000 95.80812  ? 347 THR   A OG1 1 
ATOM   2528 C  CG2 . THR   A 1 347 ? 13.58701 27.57467  24.03211  1.000 96.77939  ? 347 THR   A CG2 1 
ATOM   2529 N  N   . PRO   A 1 348 ? 16.71288 24.35793  25.43759  1.000 74.48692  ? 348 PRO   A N   1 
ATOM   2530 C  CA  . PRO   A 1 348 ? 17.74911 23.38886  25.06321  1.000 76.14587  ? 348 PRO   A CA  1 
ATOM   2531 C  C   . PRO   A 1 348 ? 17.69997 23.11973  23.56702  1.000 79.40570  ? 348 PRO   A C   1 
ATOM   2532 O  O   . PRO   A 1 348 ? 16.62653 22.93753  22.98783  1.000 82.15161  ? 348 PRO   A O   1 
ATOM   2533 C  CB  . PRO   A 1 348 ? 17.38441 22.14236  25.87919  1.000 78.12013  ? 348 PRO   A CB  1 
ATOM   2534 C  CG  . PRO   A 1 348 ? 16.51796 22.64683  26.99184  1.000 85.88838  ? 348 PRO   A CG  1 
ATOM   2535 C  CD  . PRO   A 1 348 ? 15.76411 23.80607  26.41807  1.000 81.30959  ? 348 PRO   A CD  1 
ATOM   2536 N  N   . LEU   A 1 349 ? 18.87868 23.10404  22.93932  1.000 76.01318  ? 349 LEU   A N   1 
ATOM   2537 C  CA  . LEU   A 1 349 ? 18.94075 22.92205  21.49263  1.000 70.60673  ? 349 LEU   A CA  1 
ATOM   2538 C  C   . LEU   A 1 349 ? 18.36406 21.57705  21.06882  1.000 79.07418  ? 349 LEU   A C   1 
ATOM   2539 O  O   . LEU   A 1 349 ? 17.86752 21.44136  19.94452  1.000 82.98850  ? 349 LEU   A O   1 
ATOM   2540 C  CB  . LEU   A 1 349 ? 20.38467 23.06395  21.00903  1.000 62.25024  ? 349 LEU   A CB  1 
ATOM   2541 C  CG  . LEU   A 1 349 ? 20.60804 23.06225  19.49577  1.000 67.63544  ? 349 LEU   A CG  1 
ATOM   2542 C  CD1 . LEU   A 1 349 ? 19.79926 24.16759  18.83465  1.000 77.15884  ? 349 LEU   A CD1 1 
ATOM   2543 C  CD2 . LEU   A 1 349 ? 22.08591 23.20861  19.17306  1.000 75.84557  ? 349 LEU   A CD2 1 
ATOM   2544 N  N   . CYS   A 1 350 ? 18.40573 20.58055  21.95067  1.000 79.66074  ? 350 CYS   A N   1 
ATOM   2545 C  CA  . CYS   A 1 350 ? 17.86570 19.25858  21.66607  1.000 81.56555  ? 350 CYS   A CA  1 
ATOM   2546 C  C   . CYS   A 1 350 ? 16.91258 18.85097  22.77798  1.000 80.89401  ? 350 CYS   A C   1 
ATOM   2547 O  O   . CYS   A 1 350 ? 17.28349 18.86909  23.95614  1.000 76.83540  ? 350 CYS   A O   1 
ATOM   2548 C  CB  . CYS   A 1 350 ? 18.98280 18.22008  21.52673  1.000 72.90518  ? 350 CYS   A CB  1 
ATOM   2549 S  SG  . CYS   A 1 350 ? 20.19902 18.60090  20.25346  1.000 65.72749  ? 350 CYS   A SG  1 
ATOM   2550 N  N   . THR   A 1 351 ? 15.68542 18.48851  22.40130  1.000 87.64728  ? 351 THR   A N   1 
ATOM   2551 C  CA  . THR   A 1 351 ? 14.74010 17.93236  23.35993  1.000 86.11087  ? 351 THR   A CA  1 
ATOM   2552 C  C   . THR   A 1 351 ? 14.98710 16.45355  23.62123  1.000 86.15600  ? 351 THR   A C   1 
ATOM   2553 O  O   . THR   A 1 351 ? 14.55596 15.93863  24.65837  1.000 91.63202  ? 351 THR   A O   1 
ATOM   2554 C  CB  . THR   A 1 351 ? 13.30379 18.13166  22.86970  1.000 87.39379  ? 351 THR   A CB  1 
ATOM   2555 O  OG1 . THR   A 1 351 ? 13.15375 17.54527  21.57035  1.000 89.10063  ? 351 THR   A OG1 1 
ATOM   2556 C  CG2 . THR   A 1 351 ? 12.96651 19.61329  22.79585  1.000 89.70233  ? 351 THR   A CG2 1 
ATOM   2557 N  N   . GLN   A 1 352 ? 15.67263 15.76744  22.70944  1.000 83.20727  ? 352 GLN   A N   1 
ATOM   2558 C  CA  . GLN   A 1 352 ? 15.99625 14.35620  22.85843  1.000 81.65077  ? 352 GLN   A CA  1 
ATOM   2559 C  C   . GLN   A 1 352 ? 17.15056 14.03944  21.92244  1.000 77.97774  ? 352 GLN   A C   1 
ATOM   2560 O  O   . GLN   A 1 352 ? 17.25115 14.64439  20.84904  1.000 76.15815  ? 352 GLN   A O   1 
ATOM   2561 C  CB  . GLN   A 1 352 ? 14.77888 13.47285  22.54796  1.000 81.33452  ? 352 GLN   A CB  1 
ATOM   2562 C  CG  . GLN   A 1 352 ? 14.01766 13.87564  21.29668  1.000 92.08147  ? 352 GLN   A CG  1 
ATOM   2563 C  CD  . GLN   A 1 352 ? 12.67261 13.18513  21.19363  1.000 103.45304 ? 352 GLN   A CD  1 
ATOM   2564 O  OE1 . GLN   A 1 352 ? 11.87402 13.48316  20.30555  1.000 113.03559 ? 352 GLN   A OE1 1 
ATOM   2565 N  NE2 . GLN   A 1 352 ? 12.41338 12.25726  22.10819  1.000 104.66925 ? 352 GLN   A NE2 1 
ATOM   2566 N  N   . PRO   A 1 353 ? 18.03558 13.11661  22.29439  1.000 77.22640  ? 353 PRO   A N   1 
ATOM   2567 C  CA  . PRO   A 1 353 ? 19.23759 12.87986  21.48789  1.000 75.66189  ? 353 PRO   A CA  1 
ATOM   2568 C  C   . PRO   A 1 353 ? 18.91099 12.24029  20.14920  1.000 74.19159  ? 353 PRO   A C   1 
ATOM   2569 O  O   . PRO   A 1 353 ? 17.89143 11.56860  19.97421  1.000 70.56163  ? 353 PRO   A O   1 
ATOM   2570 C  CB  . PRO   A 1 353 ? 20.06854 11.93309  22.35895  1.000 72.11959  ? 353 PRO   A CB  1 
ATOM   2571 C  CG  . PRO   A 1 353 ? 19.05787 11.22246  23.19247  1.000 67.74999  ? 353 PRO   A CG  1 
ATOM   2572 C  CD  . PRO   A 1 353 ? 17.97685 12.22947  23.46957  1.000 75.84653  ? 353 PRO   A CD  1 
ATOM   2573 N  N   . ASP   A 1 354 ? 19.81094 12.45959  19.18903  1.000 76.95387  ? 354 ASP   A N   1 
ATOM   2574 C  CA  . ASP   A 1 354 ? 19.63822 11.83626  17.88379  1.000 78.45755  ? 354 ASP   A CA  1 
ATOM   2575 C  C   . ASP   A 1 354 ? 19.88822 10.33483  17.96020  1.000 79.80637  ? 354 ASP   A C   1 
ATOM   2576 O  O   . ASP   A 1 354 ? 19.08869 9.54010   17.45171  1.000 88.43113  ? 354 ASP   A O   1 
ATOM   2577 C  CB  . ASP   A 1 354 ? 20.55504 12.48874  16.85018  1.000 81.60861  ? 354 ASP   A CB  1 
ATOM   2578 C  CG  . ASP   A 1 354 ? 20.30643 11.96733  15.45209  1.000 88.01904  ? 354 ASP   A CG  1 
ATOM   2579 O  OD1 . ASP   A 1 354 ? 19.38143 12.47190  14.78185  1.000 90.67363  ? 354 ASP   A OD1 1 
ATOM   2580 O  OD2 . ASP   A 1 354 ? 21.02199 11.03690  15.03070  1.000 90.38687  ? 354 ASP   A OD2 1 
ATOM   2581 N  N   . GLN   A 1 355 ? 20.98736 9.91947   18.59343  1.000 77.78882  ? 355 GLN   A N   1 
ATOM   2582 C  CA  . GLN   A 1 355 ? 21.29012 8.49672   18.70269  1.000 76.77092  ? 355 GLN   A CA  1 
ATOM   2583 C  C   . GLN   A 1 355 ? 21.50195 8.09461   20.15789  1.000 77.93418  ? 355 GLN   A C   1 
ATOM   2584 O  O   . GLN   A 1 355 ? 21.92718 8.89912   20.98788  1.000 77.34286  ? 355 GLN   A O   1 
ATOM   2585 C  CB  . GLN   A 1 355 ? 22.51511 8.11570   17.85640  1.000 78.42076  ? 355 GLN   A CB  1 
ATOM   2586 C  CG  . GLN   A 1 355 ? 22.21413 8.06420   16.35916  1.000 88.72146  ? 355 GLN   A CG  1 
ATOM   2587 C  CD  . GLN   A 1 355 ? 23.30729 7.38855   15.55481  1.000 100.19868 ? 355 GLN   A CD  1 
ATOM   2588 O  OE1 . GLN   A 1 355 ? 24.06446 6.57181   16.07841  1.000 96.15071  ? 355 GLN   A OE1 1 
ATOM   2589 N  NE2 . GLN   A 1 355 ? 23.39297 7.72536   14.27236  1.000 102.35967 ? 355 GLN   A NE2 1 
ATOM   2590 N  N   . VAL   A 1 356 ? 21.18679 6.83674   20.46605  1.000 79.29778  ? 356 VAL   A N   1 
ATOM   2591 C  CA  . VAL   A 1 356 ? 21.26270 6.32147   21.83104  1.000 80.68154  ? 356 VAL   A CA  1 
ATOM   2592 C  C   . VAL   A 1 356 ? 21.87939 4.93057   21.79040  1.000 75.56482  ? 356 VAL   A C   1 
ATOM   2593 O  O   . VAL   A 1 356 ? 21.33979 4.03032   21.13660  1.000 78.84724  ? 356 VAL   A O   1 
ATOM   2594 C  CB  . VAL   A 1 356 ? 19.88406 6.26241   22.51552  1.000 78.34734  ? 356 VAL   A CB  1 
ATOM   2595 C  CG1 . VAL   A 1 356 ? 20.00901 5.63921   23.89676  1.000 78.69796  ? 356 VAL   A CG1 1 
ATOM   2596 C  CG2 . VAL   A 1 356 ? 19.26342 7.64689   22.61071  1.000 76.31506  ? 356 VAL   A CG2 1 
ATOM   2597 N  N   . ILE   A 1 357 ? 23.00170 4.75160   22.48302  1.000 71.77129  ? 357 ILE   A N   1 
ATOM   2598 C  CA  . ILE   A 1 357 ? 23.59883 3.44049   22.69919  1.000 74.95805  ? 357 ILE   A CA  1 
ATOM   2599 C  C   . ILE   A 1 357 ? 23.21007 3.02315   24.11231  1.000 78.06822  ? 357 ILE   A C   1 
ATOM   2600 O  O   . ILE   A 1 357 ? 23.75330 3.53256   25.09731  1.000 78.47971  ? 357 ILE   A O   1 
ATOM   2601 C  CB  . ILE   A 1 357 ? 25.11665 3.46377   22.50561  1.000 70.66954  ? 357 ILE   A CB  1 
ATOM   2602 C  CG1 . ILE   A 1 357 ? 25.46240 3.80088   21.05447  1.000 73.20342  ? 357 ILE   A CG1 1 
ATOM   2603 C  CG2 . ILE   A 1 357 ? 25.72286 2.12835   22.90308  1.000 64.07601  ? 357 ILE   A CG2 1 
ATOM   2604 C  CD1 . ILE   A 1 357 ? 26.94316 3.76319   20.75312  1.000 69.77161  ? 357 ILE   A CD1 1 
ATOM   2605 N  N   . LYS   A 1 358 ? 22.25572 2.10198   24.21405  1.000 76.04925  ? 358 LYS   A N   1 
ATOM   2606 C  CA  . LYS   A 1 358 ? 21.72500 1.69825   25.50770  1.000 71.78345  ? 358 LYS   A CA  1 
ATOM   2607 C  C   . LYS   A 1 358 ? 22.70310 0.78330   26.23145  1.000 77.85175  ? 358 LYS   A C   1 
ATOM   2608 O  O   . LYS   A 1 358 ? 23.21708 -0.17887  25.65186  1.000 80.76989  ? 358 LYS   A O   1 
ATOM   2609 C  CB  . LYS   A 1 358 ? 20.37668 0.99965   25.33728  1.000 62.13972  ? 358 LYS   A CB  1 
ATOM   2610 C  CG  . LYS   A 1 358 ? 19.18003 1.91945   25.51002  1.000 69.23445  ? 358 LYS   A CG  1 
ATOM   2611 C  CD  . LYS   A 1 358 ? 19.17522 2.55402   26.89373  1.000 70.23188  ? 358 LYS   A CD  1 
ATOM   2612 C  CE  . LYS   A 1 358 ? 19.11570 1.49865   27.98894  1.000 67.99569  ? 358 LYS   A CE  1 
ATOM   2613 N  NZ  . LYS   A 1 358 ? 19.26994 2.09545   29.34395  1.000 78.04540  ? 358 LYS   A NZ  1 
ATOM   2614 N  N   . GLY   A 1 359 ? 22.95919 1.09148   27.50362  1.000 82.52954  ? 359 GLY   A N   1 
ATOM   2615 C  CA  . GLY   A 1 359 ? 23.77032 0.25321   28.35441  1.000 80.46550  ? 359 GLY   A CA  1 
ATOM   2616 C  C   . GLY   A 1 359 ? 22.91815 -0.63113  29.25316  1.000 81.98061  ? 359 GLY   A C   1 
ATOM   2617 O  O   . GLY   A 1 359 ? 21.69093 -0.56872  29.26612  1.000 81.51848  ? 359 GLY   A O   1 
ATOM   2618 N  N   . GLY   A 1 360 ? 23.60621 -1.47129  30.01865  1.000 81.37335  ? 360 GLY   A N   1 
ATOM   2619 C  CA  . GLY   A 1 360 ? 22.95003 -2.39659  30.91640  1.000 79.66970  ? 360 GLY   A CA  1 
ATOM   2620 C  C   . GLY   A 1 360 ? 22.46513 -1.72576  32.18515  1.000 75.00258  ? 360 GLY   A C   1 
ATOM   2621 O  O   . GLY   A 1 360 ? 22.20625 -0.52215  32.23101  1.000 68.05986  ? 360 GLY   A O   1 
ATOM   2622 N  N   . ALA   A 1 361 ? 22.33844 -2.53603  33.23207  1.000 74.62945  ? 361 ALA   A N   1 
ATOM   2623 C  CA  . ALA   A 1 361 ? 21.89445 -2.07224  34.53865  1.000 71.86196  ? 361 ALA   A CA  1 
ATOM   2624 C  C   . ALA   A 1 361 ? 22.89841 -2.52768  35.58484  1.000 73.03662  ? 361 ALA   A C   1 
ATOM   2625 O  O   . ALA   A 1 361 ? 23.27349 -3.70401  35.61893  1.000 71.32893  ? 361 ALA   A O   1 
ATOM   2626 C  CB  . ALA   A 1 361 ? 20.49535 -2.60189  34.87132  1.000 74.02622  ? 361 ALA   A CB  1 
ATOM   2627 N  N   . SER   A 1 362 ? 23.33311 -1.59756  36.43007  1.000 67.08729  ? 362 SER   A N   1 
ATOM   2628 C  CA  . SER   A 1 362 ? 24.32607 -1.90197  37.44999  1.000 69.50376  ? 362 SER   A CA  1 
ATOM   2629 C  C   . SER   A 1 362 ? 23.66636 -2.57460  38.64669  1.000 71.28164  ? 362 SER   A C   1 
ATOM   2630 O  O   . SER   A 1 362 ? 22.62883 -2.11575  39.13428  1.000 73.17743  ? 362 SER   A O   1 
ATOM   2631 C  CB  . SER   A 1 362 ? 25.04205 -0.62578  37.89054  1.000 61.10952  ? 362 SER   A CB  1 
ATOM   2632 O  OG  . SER   A 1 362 ? 25.64832 0.02542   36.78810  1.000 60.20022  ? 362 SER   A OG  1 
ATOM   2633 N  N   . ILE   A 1 363 ? 24.26779 -3.66690  39.11521  1.000 62.20455  ? 363 ILE   A N   1 
ATOM   2634 C  CA  . ILE   A 1 363 ? 23.81636 -4.32829  40.33394  1.000 59.69862  ? 363 ILE   A CA  1 
ATOM   2635 C  C   . ILE   A 1 363 ? 24.15281 -3.42534  41.51220  1.000 65.41188  ? 363 ILE   A C   1 
ATOM   2636 O  O   . ILE   A 1 363 ? 25.31613 -3.32535  41.91756  1.000 64.74749  ? 363 ILE   A O   1 
ATOM   2637 C  CB  . ILE   A 1 363 ? 24.45920 -5.71794  40.49207  1.000 59.90364  ? 363 ILE   A CB  1 
ATOM   2638 C  CG1 . ILE   A 1 363 ? 24.16187 -6.58429  39.26638  1.000 63.92051  ? 363 ILE   A CG1 1 
ATOM   2639 C  CG2 . ILE   A 1 363 ? 23.96754 -6.39167  41.76317  1.000 60.90475  ? 363 ILE   A CG2 1 
ATOM   2640 C  CD1 . ILE   A 1 363 ? 24.82789 -7.94276  39.29917  1.000 61.83010  ? 363 ILE   A CD1 1 
ATOM   2641 N  N   . ILE   A 1 364 ? 23.14240 -2.75863  42.06646  1.000 70.95705  ? 364 ILE   A N   1 
ATOM   2642 C  CA  . ILE   A 1 364 ? 23.39847 -1.73426  43.07261  1.000 68.71379  ? 364 ILE   A CA  1 
ATOM   2643 C  C   . ILE   A 1 364 ? 23.40186 -2.29176  44.49500  1.000 69.88524  ? 364 ILE   A C   1 
ATOM   2644 O  O   . ILE   A 1 364 ? 24.11295 -1.76601  45.35748  1.000 70.63007  ? 364 ILE   A O   1 
ATOM   2645 C  CB  . ILE   A 1 364 ? 22.38311 -0.58503  42.94060  1.000 66.67113  ? 364 ILE   A CB  1 
ATOM   2646 C  CG1 . ILE   A 1 364 ? 20.96238 -1.07896  43.22341  1.000 73.12960  ? 364 ILE   A CG1 1 
ATOM   2647 C  CG2 . ILE   A 1 364 ? 22.46712 0.04292   41.55809  1.000 68.24177  ? 364 ILE   A CG2 1 
ATOM   2648 C  CD1 . ILE   A 1 364 ? 19.93660 0.02967   43.31826  1.000 75.27759  ? 364 ILE   A CD1 1 
ATOM   2649 N  N   . GLN   A 1 365 ? 22.62890 -3.34145  44.77005  1.000 65.65623  ? 365 GLN   A N   1 
ATOM   2650 C  CA  . GLN   A 1 365 ? 22.52178 -3.85655  46.12749  1.000 66.76482  ? 365 GLN   A CA  1 
ATOM   2651 C  C   . GLN   A 1 365 ? 22.62233 -5.37439  46.11230  1.000 75.29342  ? 365 GLN   A C   1 
ATOM   2652 O  O   . GLN   A 1 365 ? 22.26107 -6.02580  45.13053  1.000 79.87757  ? 365 GLN   A O   1 
ATOM   2653 C  CB  . GLN   A 1 365 ? 21.20887 -3.41446  46.79212  1.000 74.61109  ? 365 GLN   A CB  1 
ATOM   2654 C  CG  . GLN   A 1 365 ? 21.16381 -3.63719  48.29650  1.000 80.29043  ? 365 GLN   A CG  1 
ATOM   2655 C  CD  . GLN   A 1 365 ? 19.90766 -3.07882  48.93339  1.000 85.72909  ? 365 GLN   A CD  1 
ATOM   2656 O  OE1 . GLN   A 1 365 ? 19.21900 -2.24325  48.34785  1.000 84.55646  ? 365 GLN   A OE1 1 
ATOM   2657 N  NE2 . GLN   A 1 365 ? 19.60120 -3.54089  50.14015  1.000 86.64075  ? 365 GLN   A NE2 1 
ATOM   2658 N  N   . CYS   A 1 366 ? 23.11137 -5.93157  47.21828  1.000 76.22896  ? 366 CYS   A N   1 
ATOM   2659 C  CA  . CYS   A 1 366 ? 23.29286 -7.36968  47.33959  1.000 71.76514  ? 366 CYS   A CA  1 
ATOM   2660 C  C   . CYS   A 1 366 ? 23.12262 -7.78246  48.79377  1.000 74.23470  ? 366 CYS   A C   1 
ATOM   2661 O  O   . CYS   A 1 366 ? 23.35342 -6.98988  49.71100  1.000 82.25850  ? 366 CYS   A O   1 
ATOM   2662 C  CB  . CYS   A 1 366 ? 24.66996 -7.80349  46.82530  1.000 74.68532  ? 366 CYS   A CB  1 
ATOM   2663 S  SG  . CYS   A 1 366 ? 25.28250 -9.33908  47.54815  1.000 84.35879  ? 366 CYS   A SG  1 
ATOM   2664 N  N   . HIS   A 1 367 ? 22.71210 -9.03378  48.99245  1.000 71.91948  ? 367 HIS   A N   1 
ATOM   2665 C  CA  . HIS   A 1 367 ? 22.58488 -9.59734  50.32854  1.000 68.53700  ? 367 HIS   A CA  1 
ATOM   2666 C  C   . HIS   A 1 367 ? 22.92057 -11.08014 50.28363  1.000 67.60898  ? 367 HIS   A C   1 
ATOM   2667 O  O   . HIS   A 1 367 ? 22.46687 -11.80278 49.39203  1.000 74.27029  ? 367 HIS   A O   1 
ATOM   2668 C  CB  . HIS   A 1 367 ? 21.17655 -9.39810  50.89791  1.000 71.37013  ? 367 HIS   A CB  1 
ATOM   2669 C  CG  . HIS   A 1 367 ? 20.96262 -10.06402 52.22193  1.000 73.80945  ? 367 HIS   A CG  1 
ATOM   2670 N  ND1 . HIS   A 1 367 ? 21.51015 -9.58641  53.39329  1.000 83.12404  ? 367 HIS   A ND1 1 
ATOM   2671 C  CD2 . HIS   A 1 367 ? 20.26621 -11.17546 52.55851  1.000 76.54678  ? 367 HIS   A CD2 1 
ATOM   2672 C  CE1 . HIS   A 1 367 ? 21.15657 -10.37212 54.39488  1.000 84.84339  ? 367 HIS   A CE1 1 
ATOM   2673 N  NE2 . HIS   A 1 367 ? 20.40151 -11.34397 53.91527  1.000 80.84105  ? 367 HIS   A NE2 1 
ATOM   2674 N  N   . ILE   A 1 368 ? 23.71185 -11.52671 51.25395  1.000 67.24489  ? 368 ILE   A N   1 
ATOM   2675 C  CA  . ILE   A 1 368 ? 24.10177 -12.92611 51.37443  1.000 71.93537  ? 368 ILE   A CA  1 
ATOM   2676 C  C   . ILE   A 1 368 ? 23.16059 -13.60298 52.35987  1.000 74.78363  ? 368 ILE   A C   1 
ATOM   2677 O  O   . ILE   A 1 368 ? 22.91869 -13.08323 53.45688  1.000 77.81976  ? 368 ILE   A O   1 
ATOM   2678 C  CB  . ILE   A 1 368 ? 25.56595 -13.05960 51.82497  1.000 67.14574  ? 368 ILE   A CB  1 
ATOM   2679 C  CG1 . ILE   A 1 368 ? 26.46576 -12.16571 50.96956  1.000 69.89557  ? 368 ILE   A CG1 1 
ATOM   2680 C  CG2 . ILE   A 1 368 ? 26.01974 -14.50864 51.73560  1.000 61.36389  ? 368 ILE   A CG2 1 
ATOM   2681 C  CD1 . ILE   A 1 368 ? 27.92282 -12.20091 51.37122  1.000 70.37304  ? 368 ILE   A CD1 1 
ATOM   2682 N  N   . LEU   A 1 369 ? 22.62959 -14.76022 51.97254  1.000 69.77038  ? 369 LEU   A N   1 
ATOM   2683 C  CA  . LEU   A 1 369 ? 21.67320 -15.46612 52.80994  1.000 69.58343  ? 369 LEU   A CA  1 
ATOM   2684 C  C   . LEU   A 1 369 ? 22.36643 -16.06296 54.03463  1.000 71.91767  ? 369 LEU   A C   1 
ATOM   2685 O  O   . LEU   A 1 369 ? 23.59194 -16.02333 54.17774  1.000 78.20328  ? 369 LEU   A O   1 
ATOM   2686 C  CB  . LEU   A 1 369 ? 20.96216 -16.56019 52.01254  1.000 70.76553  ? 369 LEU   A CB  1 
ATOM   2687 C  CG  . LEU   A 1 369 ? 19.82284 -16.13115 51.08157  1.000 75.89395  ? 369 LEU   A CG  1 
ATOM   2688 C  CD1 . LEU   A 1 369 ? 18.84358 -15.22559 51.81683  1.000 75.80355  ? 369 LEU   A CD1 1 
ATOM   2689 C  CD2 . LEU   A 1 369 ? 20.34027 -15.46010 49.81400  1.000 73.98154  ? 369 LEU   A CD2 1 
ATOM   2690 N  N   . ASN   A 1 370 ? 21.55293 -16.62898 54.92984  1.000 71.65788  ? 370 ASN   A N   1 
ATOM   2691 C  CA  . ASN   A 1 370 ? 22.07214 -17.16601 56.18233  1.000 76.48125  ? 370 ASN   A CA  1 
ATOM   2692 C  C   . ASN   A 1 370 ? 22.91707 -18.41668 55.97895  1.000 65.58261  ? 370 ASN   A C   1 
ATOM   2693 O  O   . ASN   A 1 370 ? 23.71919 -18.75450 56.85613  1.000 65.15851  ? 370 ASN   A O   1 
ATOM   2694 C  CB  . ASN   A 1 370 ? 20.91996 -17.46826 57.14146  1.000 81.38976  ? 370 ASN   A CB  1 
ATOM   2695 C  CG  . ASN   A 1 370 ? 20.08316 -16.24242 57.45195  1.000 84.65869  ? 370 ASN   A CG  1 
ATOM   2696 O  OD1 . ASN   A 1 370 ? 20.08589 -15.26739 56.70010  1.000 87.29795  ? 370 ASN   A OD1 1 
ATOM   2697 N  ND2 . ASN   A 1 370 ? 19.36067 -16.28598 58.56539  1.000 84.28274  ? 370 ASN   A ND2 1 
ATOM   2698 N  N   . ASP   A 1 371 ? 22.75816 -19.10901 54.85405  1.000 62.58945  ? 371 ASP   A N   1 
ATOM   2699 C  CA  . ASP   A 1 371 ? 23.55085 -20.29433 54.55799  1.000 69.24391  ? 371 ASP   A CA  1 
ATOM   2700 C  C   . ASP   A 1 371 ? 24.88115 -19.96575 53.89316  1.000 66.92080  ? 371 ASP   A C   1 
ATOM   2701 O  O   . ASP   A 1 371 ? 25.67543 -20.88026 53.64877  1.000 62.93142  ? 371 ASP   A O   1 
ATOM   2702 C  CB  . ASP   A 1 371 ? 22.75341 -21.25730 53.66934  1.000 74.55488  ? 371 ASP   A CB  1 
ATOM   2703 C  CG  . ASP   A 1 371 ? 22.30363 -20.61867 52.36676  1.000 71.66461  ? 371 ASP   A CG  1 
ATOM   2704 O  OD1 . ASP   A 1 371 ? 22.49185 -19.39564 52.20031  1.000 74.53126  ? 371 ASP   A OD1 1 
ATOM   2705 O  OD2 . ASP   A 1 371 ? 21.76045 -21.34274 51.50586  1.000 65.12859  ? 371 ASP   A OD2 1 
ATOM   2706 N  N   . LYS   A 1 372 ? 25.13282 -18.68952 53.58901  1.000 63.98584  ? 372 LYS   A N   1 
ATOM   2707 C  CA  . LYS   A 1 372 ? 26.36656 -18.24791 52.93075  1.000 61.44353  ? 372 LYS   A CA  1 
ATOM   2708 C  C   . LYS   A 1 372 ? 26.63805 -19.03604 51.65148  1.000 65.44299  ? 372 LYS   A C   1 
ATOM   2709 O  O   . LYS   A 1 372 ? 27.78735 -19.20243 51.23667  1.000 65.43658  ? 372 LYS   A O   1 
ATOM   2710 C  CB  . LYS   A 1 372 ? 27.56441 -18.33422 53.87889  1.000 57.36038  ? 372 LYS   A CB  1 
ATOM   2711 C  CG  . LYS   A 1 372 ? 27.32767 -17.70799 55.24140  1.000 58.97737  ? 372 LYS   A CG  1 
ATOM   2712 C  CD  . LYS   A 1 372 ? 26.85046 -16.27039 55.13994  1.000 61.22284  ? 372 LYS   A CD  1 
ATOM   2713 C  CE  . LYS   A 1 372 ? 26.65095 -15.66573 56.52220  1.000 56.43194  ? 372 LYS   A CE  1 
ATOM   2714 N  NZ  . LYS   A 1 372 ? 25.74718 -16.49017 57.37185  1.000 61.61545  ? 372 LYS   A NZ  1 
ATOM   2715 N  N   . ARG   A 1 373 ? 25.57521 -19.53377 51.02269  1.000 65.42730  ? 373 ARG   A N   1 
ATOM   2716 C  CA  . ARG   A 1 373 ? 25.67214 -20.27064 49.77165  1.000 64.06210  ? 373 ARG   A CA  1 
ATOM   2717 C  C   . ARG   A 1 373 ? 25.08052 -19.52858 48.58746  1.000 63.62372  ? 373 ARG   A C   1 
ATOM   2718 O  O   . ARG   A 1 373 ? 25.59104 -19.66075 47.47357  1.000 63.07141  ? 373 ARG   A O   1 
ATOM   2719 C  CB  . ARG   A 1 373 ? 24.96759 -21.62722 49.89271  1.000 73.64991  ? 373 ARG   A CB  1 
ATOM   2720 C  CG  . ARG   A 1 373 ? 25.64339 -22.62488 50.81352  1.000 76.71612  ? 373 ARG   A CG  1 
ATOM   2721 C  CD  . ARG   A 1 373 ? 25.08788 -24.00824 50.54596  1.000 65.96465  ? 373 ARG   A CD  1 
ATOM   2722 N  NE  . ARG   A 1 373 ? 25.23165 -24.35684 49.13772  1.000 66.73286  ? 373 ARG   A NE  1 
ATOM   2723 C  CZ  . ARG   A 1 373 ? 24.42810 -25.18251 48.48238  1.000 76.35189  ? 373 ARG   A CZ  1 
ATOM   2724 N  NH1 . ARG   A 1 373 ? 23.39476 -25.75727 49.07570  1.000 79.16689  ? 373 ARG   A NH1 1 
ATOM   2725 N  NH2 . ARG   A 1 373 ? 24.66211 -25.43071 47.19683  1.000 81.47321  ? 373 ARG   A NH2 1 
ATOM   2726 N  N   . HIS   A 1 374 ? 24.02119 -18.75557 48.80102  1.000 63.04178  ? 374 HIS   A N   1 
ATOM   2727 C  CA  . HIS   A 1 374 ? 23.32975 -18.06149 47.72970  1.000 67.01687  ? 374 HIS   A CA  1 
ATOM   2728 C  C   . HIS   A 1 374 ? 23.28956 -16.56544 48.01080  1.000 68.50882  ? 374 HIS   A C   1 
ATOM   2729 O  O   . HIS   A 1 374 ? 23.52642 -16.11182 49.13382  1.000 70.92818  ? 374 HIS   A O   1 
ATOM   2730 C  CB  . HIS   A 1 374 ? 21.91191 -18.61028 47.54821  1.000 72.62766  ? 374 HIS   A CB  1 
ATOM   2731 C  CG  . HIS   A 1 374 ? 21.87441 -20.05123 47.14289  1.000 69.13128  ? 374 HIS   A CG  1 
ATOM   2732 N  ND1 . HIS   A 1 374 ? 22.01142 -21.08236 48.04707  1.000 69.05174  ? 374 HIS   A ND1 1 
ATOM   2733 C  CD2 . HIS   A 1 374 ? 21.72450 -20.63308 45.92931  1.000 65.64404  ? 374 HIS   A CD2 1 
ATOM   2734 C  CE1 . HIS   A 1 374 ? 21.94218 -22.23727 47.40927  1.000 75.04634  ? 374 HIS   A CE1 1 
ATOM   2735 N  NE2 . HIS   A 1 374 ? 21.76863 -21.99262 46.12298  1.000 73.46577  ? 374 HIS   A NE2 1 
ATOM   2736 N  N   . ILE   A 1 375 ? 22.98289 -15.80148 46.96630  1.000 66.73430  ? 375 ILE   A N   1 
ATOM   2737 C  CA  . ILE   A 1 375 ? 23.04519 -14.34542 47.00349  1.000 63.95037  ? 375 ILE   A CA  1 
ATOM   2738 C  C   . ILE   A 1 375 ? 21.78620 -13.78777 46.35351  1.000 69.52622  ? 375 ILE   A C   1 
ATOM   2739 O  O   . ILE   A 1 375 ? 21.28450 -14.34411 45.37177  1.000 71.35438  ? 375 ILE   A O   1 
ATOM   2740 C  CB  . ILE   A 1 375 ? 24.31867 -13.82975 46.29634  1.000 66.62186  ? 375 ILE   A CB  1 
ATOM   2741 C  CG1 . ILE   A 1 375 ? 25.56643 -14.18595 47.10959  1.000 76.09552  ? 375 ILE   A CG1 1 
ATOM   2742 C  CG2 . ILE   A 1 375 ? 24.25221 -12.33627 46.05936  1.000 59.97014  ? 375 ILE   A CG2 1 
ATOM   2743 C  CD1 . ILE   A 1 375 ? 26.85456 -13.67027 46.50675  1.000 78.76769  ? 375 ILE   A CD1 1 
ATOM   2744 N  N   . LEU   A 1 376 ? 21.26445 -12.69663 46.91077  1.000 72.80960  ? 376 LEU   A N   1 
ATOM   2745 C  CA  . LEU   A 1 376 ? 20.10429 -12.00652 46.36230  1.000 71.15953  ? 376 LEU   A CA  1 
ATOM   2746 C  C   . LEU   A 1 376 ? 20.52979 -10.59790 45.97402  1.000 67.33610  ? 376 LEU   A C   1 
ATOM   2747 O  O   . LEU   A 1 376 ? 20.93474 -9.81076  46.83615  1.000 70.77723  ? 376 LEU   A O   1 
ATOM   2748 C  CB  . LEU   A 1 376 ? 18.95893 -11.97604 47.37568  1.000 66.57542  ? 376 LEU   A CB  1 
ATOM   2749 C  CG  . LEU   A 1 376 ? 17.54125 -11.94841 46.80639  1.000 68.79974  ? 376 LEU   A CG  1 
ATOM   2750 C  CD1 . LEU   A 1 376 ? 17.31705 -13.12933 45.87462  1.000 62.27080  ? 376 LEU   A CD1 1 
ATOM   2751 C  CD2 . LEU   A 1 376 ? 16.52027 -11.95009 47.93089  1.000 76.76172  ? 376 LEU   A CD2 1 
ATOM   2752 N  N   . THR   A 1 377 ? 20.44891 -10.28655 44.68348  1.000 64.30970  ? 377 THR   A N   1 
ATOM   2753 C  CA  . THR   A 1 377 ? 20.92826 -9.01928  44.15257  1.000 68.37642  ? 377 THR   A CA  1 
ATOM   2754 C  C   . THR   A 1 377 ? 19.77694 -8.18545  43.60673  1.000 74.50375  ? 377 THR   A C   1 
ATOM   2755 O  O   . THR   A 1 377 ? 18.72990 -8.70649  43.21677  1.000 79.92099  ? 377 THR   A O   1 
ATOM   2756 C  CB  . THR   A 1 377 ? 21.96447 -9.23982  43.04532  1.000 62.14394  ? 377 THR   A CB  1 
ATOM   2757 O  OG1 . THR   A 1 377 ? 21.37700 -10.00091 41.98230  1.000 62.08647  ? 377 THR   A OG1 1 
ATOM   2758 C  CG2 . THR   A 1 377 ? 23.16914 -9.98110  43.58764  1.000 64.75713  ? 377 THR   A CG2 1 
ATOM   2759 N  N   . LYS   A 1 378 ? 20.00339 -6.87374  43.56544  1.000 70.83610  ? 378 LYS   A N   1 
ATOM   2760 C  CA  . LYS   A 1 378 ? 19.03492 -5.90534  43.07135  1.000 72.72770  ? 378 LYS   A CA  1 
ATOM   2761 C  C   . LYS   A 1 378 ? 19.77413 -4.86675  42.24247  1.000 75.57877  ? 378 LYS   A C   1 
ATOM   2762 O  O   . LYS   A 1 378 ? 20.73629 -4.25772  42.72302  1.000 74.73104  ? 378 LYS   A O   1 
ATOM   2763 C  CB  . LYS   A 1 378 ? 18.28586 -5.23519  44.22928  1.000 74.24569  ? 378 LYS   A CB  1 
ATOM   2764 C  CG  . LYS   A 1 378 ? 17.26358 -4.19432  43.80783  1.000 78.29992  ? 378 LYS   A CG  1 
ATOM   2765 C  CD  . LYS   A 1 378 ? 16.55216 -3.61532  45.02158  1.000 76.04272  ? 378 LYS   A CD  1 
ATOM   2766 C  CE  . LYS   A 1 378 ? 15.49662 -2.59949  44.61911  1.000 72.43366  ? 378 LYS   A CE  1 
ATOM   2767 N  NZ  . LYS   A 1 378 ? 14.76031 -2.06883  45.80005  1.000 72.49413  ? 378 LYS   A NZ  1 
ATOM   2768 N  N   . ASP   A 1 379 ? 19.32625 -4.67114  41.00565  1.000 73.57975  ? 379 ASP   A N   1 
ATOM   2769 C  CA  . ASP   A 1 379 ? 19.97812 -3.78564  40.05570  1.000 67.91363  ? 379 ASP   A CA  1 
ATOM   2770 C  C   . ASP   A 1 379 ? 19.31138 -2.40664  40.07696  1.000 71.24462  ? 379 ASP   A C   1 
ATOM   2771 O  O   . ASP   A 1 379 ? 18.61656 -2.05036  41.03572  1.000 75.50479  ? 379 ASP   A O   1 
ATOM   2772 C  CB  . ASP   A 1 379 ? 19.95521 -4.42991  38.66256  1.000 72.41640  ? 379 ASP   A CB  1 
ATOM   2773 C  CG  . ASP   A 1 379 ? 18.56248 -4.86398  38.23807  1.000 74.68459  ? 379 ASP   A CG  1 
ATOM   2774 O  OD1 . ASP   A 1 379 ? 17.65639 -4.00616  38.17675  1.000 75.49751  ? 379 ASP   A OD1 1 
ATOM   2775 O  OD2 . ASP   A 1 379 ? 18.37696 -6.06590  37.95330  1.000 68.67712  ? 379 ASP   A OD2 1 
ATOM   2776 N  N   . THR   A 1 380 ? 19.52012 -1.62202  39.01558  1.000 71.89146  ? 380 THR   A N   1 
ATOM   2777 C  CA  . THR   A 1 380 ? 18.94533 -0.28196  38.95578  1.000 74.76700  ? 380 THR   A CA  1 
ATOM   2778 C  C   . THR   A 1 380 ? 17.44349 -0.32146  38.70642  1.000 82.24853  ? 380 THR   A C   1 
ATOM   2779 O  O   . THR   A 1 380 ? 16.70763 0.52309   39.22970  1.000 86.46028  ? 380 THR   A O   1 
ATOM   2780 C  CB  . THR   A 1 380 ? 19.63248 0.54102   37.86529  1.000 69.09763  ? 380 THR   A CB  1 
ATOM   2781 O  OG1 . THR   A 1 380 ? 19.35972 -0.03857  36.58323  1.000 67.38066  ? 380 THR   A OG1 1 
ATOM   2782 C  CG2 . THR   A 1 380 ? 21.13623 0.57413   38.08892  1.000 71.32225  ? 380 THR   A CG2 1 
ATOM   2783 N  N   . ASN   A 1 381 ? 16.97288 -1.28296  37.91508  1.000 80.60392  ? 381 ASN   A N   1 
ATOM   2784 C  CA  . ASN   A 1 381 ? 15.55692 -1.41336  37.59715  1.000 74.13450  ? 381 ASN   A CA  1 
ATOM   2785 C  C   . ASN   A 1 381 ? 14.77427 -2.15578  38.67278  1.000 73.78178  ? 381 ASN   A C   1 
ATOM   2786 O  O   . ASN   A 1 381 ? 13.64357 -2.57993  38.40967  1.000 75.84402  ? 381 ASN   A O   1 
ATOM   2787 C  CB  . ASN   A 1 381 ? 15.38808 -2.12262  36.25127  1.000 73.05086  ? 381 ASN   A CB  1 
ATOM   2788 C  CG  . ASN   A 1 381 ? 16.20995 -1.48352  35.15030  1.000 73.07788  ? 381 ASN   A CG  1 
ATOM   2789 O  OD1 . ASN   A 1 381 ? 16.35202 -0.26208  35.09497  1.000 85.37373  ? 381 ASN   A OD1 1 
ATOM   2790 N  ND2 . ASN   A 1 381 ? 16.76287 -2.30941  34.26956  1.000 66.52794  ? 381 ASN   A ND2 1 
ATOM   2791 N  N   . ASN   A 1 382 ? 15.35447 -2.32721  39.86174  1.000 73.05278  ? 382 ASN   A N   1 
ATOM   2792 C  CA  . ASN   A 1 382 ? 14.73095 -3.01668  40.99051  1.000 71.51666  ? 382 ASN   A CA  1 
ATOM   2793 C  C   . ASN   A 1 382 ? 14.41840 -4.47862  40.68496  1.000 72.30007  ? 382 ASN   A C   1 
ATOM   2794 O  O   . ASN   A 1 382 ? 13.63085 -5.10834  41.39812  1.000 75.80470  ? 382 ASN   A O   1 
ATOM   2795 C  CB  . ASN   A 1 382 ? 13.46142 -2.29284  41.45682  1.000 74.73283  ? 382 ASN   A CB  1 
ATOM   2796 C  CG  . ASN   A 1 382 ? 13.71940 -0.84696  41.83114  1.000 77.65404  ? 382 ASN   A CG  1 
ATOM   2797 O  OD1 . ASN   A 1 382 ? 14.82902 -0.48216  42.21990  1.000 78.68985  ? 382 ASN   A OD1 1 
ATOM   2798 N  ND2 . ASN   A 1 382 ? 12.69165 -0.01404  41.71594  1.000 82.57127  ? 382 ASN   A ND2 1 
ATOM   2799 N  N   . ASN   A 1 383 ? 15.02090 -5.03883  39.63849  1.000 74.63364  ? 383 ASN   A N   1 
ATOM   2800 C  CA  . ASN   A 1 383 ? 14.83979 -6.45036  39.32388  1.000 83.19851  ? 383 ASN   A CA  1 
ATOM   2801 C  C   . ASN   A 1 383 ? 15.75084 -7.28586  40.21432  1.000 83.93667  ? 383 ASN   A C   1 
ATOM   2802 O  O   . ASN   A 1 383 ? 16.97660 -7.13160  40.18109  1.000 81.57571  ? 383 ASN   A O   1 
ATOM   2803 C  CB  . ASN   A 1 383 ? 15.12663 -6.71944  37.84818  1.000 87.93035  ? 383 ASN   A CB  1 
ATOM   2804 C  CG  . ASN   A 1 383 ? 13.94442 -6.39350  36.95553  1.000 90.51003  ? 383 ASN   A CG  1 
ATOM   2805 O  OD1 . ASN   A 1 383 ? 13.16629 -5.48422  37.24272  1.000 89.86312  ? 383 ASN   A OD1 1 
ATOM   2806 N  ND2 . ASN   A 1 383 ? 13.79840 -7.14479  35.86956  1.000 95.79833  ? 383 ASN   A ND2 1 
ATOM   2807 N  N   . VAL   A 1 384 ? 15.15355 -8.16291  41.00614  1.000 84.10511  ? 384 VAL   A N   1 
ATOM   2808 C  CA  . VAL   A 1 384 ? 15.88336 -8.99489  41.95357  1.000 74.07155  ? 384 VAL   A CA  1 
ATOM   2809 C  C   . VAL   A 1 384 ? 16.30118 -10.28538 41.26455  1.000 74.52152  ? 384 VAL   A C   1 
ATOM   2810 O  O   . VAL   A 1 384 ? 15.55644 -10.84796 40.45336  1.000 83.41786  ? 384 VAL   A O   1 
ATOM   2811 C  CB  . VAL   A 1 384 ? 15.02593 -9.27268  43.20257  1.000 66.82164  ? 384 VAL   A CB  1 
ATOM   2812 C  CG1 . VAL   A 1 384 ? 15.80121 -10.09600 44.21466  1.000 65.26881  ? 384 VAL   A CG1 1 
ATOM   2813 C  CG2 . VAL   A 1 384 ? 14.56336 -7.96279  43.82205  1.000 74.55567  ? 384 VAL   A CG2 1 
ATOM   2814 N  N   . ALA   A 1 385 ? 17.50621 -10.74944 41.58155  1.000 70.99946  ? 385 ALA   A N   1 
ATOM   2815 C  CA  . ALA   A 1 385 ? 18.05732 -11.96712 41.00862  1.000 73.89741  ? 385 ALA   A CA  1 
ATOM   2816 C  C   . ALA   A 1 385 ? 18.63076 -12.84414 42.11260  1.000 67.63235  ? 385 ALA   A C   1 
ATOM   2817 O  O   . ALA   A 1 385 ? 19.09477 -12.35085 43.14476  1.000 67.71173  ? 385 ALA   A O   1 
ATOM   2818 C  CB  . ALA   A 1 385 ? 19.13915 -11.65845 39.96497  1.000 73.93166  ? 385 ALA   A CB  1 
ATOM   2819 N  N   . TYR   A 1 386 ? 18.59581 -14.15401 41.87728  1.000 68.74581  ? 386 TYR   A N   1 
ATOM   2820 C  CA  . TYR   A 1 386 ? 19.04424 -15.15758 42.83374  1.000 66.62458  ? 386 TYR   A CA  1 
ATOM   2821 C  C   . TYR   A 1 386 ? 20.23358 -15.90275 42.24433  1.000 66.36561  ? 386 TYR   A C   1 
ATOM   2822 O  O   . TYR   A 1 386 ? 20.16070 -16.39895 41.11528  1.000 67.28986  ? 386 TYR   A O   1 
ATOM   2823 C  CB  . TYR   A 1 386 ? 17.90294 -16.12354 43.16845  1.000 71.52824  ? 386 TYR   A CB  1 
ATOM   2824 C  CG  . TYR   A 1 386 ? 18.17889 -17.08170 44.30562  1.000 71.94244  ? 386 TYR   A CG  1 
ATOM   2825 C  CD1 . TYR   A 1 386 ? 18.34575 -16.62222 45.60554  1.000 67.08428  ? 386 TYR   A CD1 1 
ATOM   2826 C  CD2 . TYR   A 1 386 ? 18.23873 -18.45040 44.08300  1.000 74.03588  ? 386 TYR   A CD2 1 
ATOM   2827 C  CE1 . TYR   A 1 386 ? 18.58595 -17.49966 46.64749  1.000 63.18730  ? 386 TYR   A CE1 1 
ATOM   2828 C  CE2 . TYR   A 1 386 ? 18.47756 -19.33415 45.11623  1.000 68.23247  ? 386 TYR   A CE2 1 
ATOM   2829 C  CZ  . TYR   A 1 386 ? 18.64949 -18.85446 46.39586  1.000 67.00017  ? 386 TYR   A CZ  1 
ATOM   2830 O  OH  . TYR   A 1 386 ? 18.88574 -19.73457 47.42640  1.000 78.84313  ? 386 TYR   A OH  1 
ATOM   2831 N  N   . TRP   A 1 387 ? 21.32303 -15.97946 43.00668  1.000 61.94723  ? 387 TRP   A N   1 
ATOM   2832 C  CA  . TRP   A 1 387 ? 22.58641 -16.51337 42.52318  1.000 61.18805  ? 387 TRP   A CA  1 
ATOM   2833 C  C   . TRP   A 1 387 ? 23.12098 -17.54864 43.50198  1.000 63.93806  ? 387 TRP   A C   1 
ATOM   2834 O  O   . TRP   A 1 387 ? 22.74650 -17.57778 44.67672  1.000 71.60817  ? 387 TRP   A O   1 
ATOM   2835 C  CB  . TRP   A 1 387 ? 23.63820 -15.40660 42.34169  1.000 60.92417  ? 387 TRP   A CB  1 
ATOM   2836 C  CG  . TRP   A 1 387 ? 23.12255 -14.14876 41.70957  1.000 62.51866  ? 387 TRP   A CG  1 
ATOM   2837 C  CD1 . TRP   A 1 387 ? 22.28544 -13.22992 42.27408  1.000 63.34660  ? 387 TRP   A CD1 1 
ATOM   2838 C  CD2 . TRP   A 1 387 ? 23.43335 -13.65592 40.40093  1.000 62.37261  ? 387 TRP   A CD2 1 
ATOM   2839 N  NE1 . TRP   A 1 387 ? 22.04413 -12.20552 41.39338  1.000 64.48076  ? 387 TRP   A NE1 1 
ATOM   2840 C  CE2 . TRP   A 1 387 ? 22.73876 -12.44126 40.23659  1.000 61.43629  ? 387 TRP   A CE2 1 
ATOM   2841 C  CE3 . TRP   A 1 387 ? 24.22841 -14.12528 39.35142  1.000 64.26154  ? 387 TRP   A CE3 1 
ATOM   2842 C  CZ2 . TRP   A 1 387 ? 22.81310 -11.69132 39.06531  1.000 63.03682  ? 387 TRP   A CZ2 1 
ATOM   2843 C  CZ3 . TRP   A 1 387 ? 24.30048 -13.37955 38.18914  1.000 68.85503  ? 387 TRP   A CZ3 1 
ATOM   2844 C  CH2 . TRP   A 1 387 ? 23.59781 -12.17569 38.05600  1.000 65.89309  ? 387 TRP   A CH2 1 
ATOM   2845 N  N   . ASP   A 1 388 ? 24.01804 -18.39414 43.00088  1.000 60.54315  ? 388 ASP   A N   1 
ATOM   2846 C  CA  . ASP   A 1 388 ? 24.75860 -19.35533 43.81561  1.000 56.28225  ? 388 ASP   A CA  1 
ATOM   2847 C  C   . ASP   A 1 388 ? 26.23399 -18.98310 43.70757  1.000 55.85738  ? 388 ASP   A C   1 
ATOM   2848 O  O   . ASP   A 1 388 ? 26.87948 -19.26610 42.69319  1.000 61.55212  ? 388 ASP   A O   1 
ATOM   2849 C  CB  . ASP   A 1 388 ? 24.50087 -20.78951 43.35776  1.000 61.64488  ? 388 ASP   A CB  1 
ATOM   2850 C  CG  . ASP   A 1 388 ? 25.12888 -21.82242 44.28031  1.000 69.39172  ? 388 ASP   A CG  1 
ATOM   2851 O  OD1 . ASP   A 1 388 ? 25.71186 -21.43324 45.31360  1.000 70.97927  ? 388 ASP   A OD1 1 
ATOM   2852 O  OD2 . ASP   A 1 388 ? 25.03798 -23.02899 43.97200  1.000 69.43067  ? 388 ASP   A OD2 1 
ATOM   2853 N  N   . VAL   A 1 389 ? 26.76194 -18.34246 44.75432  1.000 56.63002  ? 389 VAL   A N   1 
ATOM   2854 C  CA  . VAL   A 1 389 ? 28.14943 -17.88649 44.73284  1.000 61.46708  ? 389 VAL   A CA  1 
ATOM   2855 C  C   . VAL   A 1 389 ? 29.10721 -19.06690 44.63768  1.000 60.58258  ? 389 VAL   A C   1 
ATOM   2856 O  O   . VAL   A 1 389 ? 30.18988 -18.95443 44.04793  1.000 56.88981  ? 389 VAL   A O   1 
ATOM   2857 C  CB  . VAL   A 1 389 ? 28.43538 -17.00910 45.97072  1.000 59.27156  ? 389 VAL   A CB  1 
ATOM   2858 C  CG1 . VAL   A 1 389 ? 28.17729 -17.78198 47.25461  1.000 61.40352  ? 389 VAL   A CG1 1 
ATOM   2859 C  CG2 . VAL   A 1 389 ? 29.85703 -16.47691 45.94104  1.000 58.01539  ? 389 VAL   A CG2 1 
ATOM   2860 N  N   . LEU   A 1 390 ? 28.72343 -20.21739 45.19378  1.000 65.60030  ? 390 LEU   A N   1 
ATOM   2861 C  CA  . LEU   A 1 390 ? 29.56270 -21.40756 45.10548  1.000 67.37770  ? 390 LEU   A CA  1 
ATOM   2862 C  C   . LEU   A 1 390 ? 29.67040 -21.89328 43.66416  1.000 61.96094  ? 390 LEU   A C   1 
ATOM   2863 O  O   . LEU   A 1 390 ? 30.77155 -22.02148 43.11881  1.000 59.64744  ? 390 LEU   A O   1 
ATOM   2864 C  CB  . LEU   A 1 390 ? 29.00453 -22.50619 46.01249  1.000 65.95966  ? 390 LEU   A CB  1 
ATOM   2865 C  CG  . LEU   A 1 390 ? 29.84586 -23.77442 46.15969  1.000 56.31527  ? 390 LEU   A CG  1 
ATOM   2866 C  CD1 . LEU   A 1 390 ? 31.21903 -23.44576 46.72477  1.000 59.07372  ? 390 LEU   A CD1 1 
ATOM   2867 C  CD2 . LEU   A 1 390 ? 29.12765 -24.78142 47.04115  1.000 55.39024  ? 390 LEU   A CD2 1 
ATOM   2868 N  N   . LYS   A 1 391 ? 28.53108 -22.16471 43.02489  1.000 62.25451  ? 391 LYS   A N   1 
ATOM   2869 C  CA  . LYS   A 1 391 ? 28.55083 -22.59703 41.63216  1.000 65.00553  ? 391 LYS   A CA  1 
ATOM   2870 C  C   . LYS   A 1 391 ? 28.92187 -21.46991 40.67804  1.000 66.39290  ? 391 LYS   A C   1 
ATOM   2871 O  O   . LYS   A 1 391 ? 29.23890 -21.74413 39.51505  1.000 62.62622  ? 391 LYS   A O   1 
ATOM   2872 C  CB  . LYS   A 1 391 ? 27.19259 -23.18334 41.24130  1.000 67.68092  ? 391 LYS   A CB  1 
ATOM   2873 C  CG  . LYS   A 1 391 ? 26.92539 -24.58105 41.77828  1.000 62.35686  ? 391 LYS   A CG  1 
ATOM   2874 C  CD  . LYS   A 1 391 ? 25.50917 -25.01818 41.43548  1.000 60.18998  ? 391 LYS   A CD  1 
ATOM   2875 C  CE  . LYS   A 1 391 ? 25.28688 -26.49439 41.71725  1.000 60.35559  ? 391 LYS   A CE  1 
ATOM   2876 N  NZ  . LYS   A 1 391 ? 26.07423 -27.35807 40.79523  1.000 62.00598  ? 391 LYS   A NZ  1 
ATOM   2877 N  N   . ALA   A 1 392 ? 28.89095 -20.22010 41.14451  1.000 66.07499  ? 392 ALA   A N   1 
ATOM   2878 C  CA  . ALA   A 1 392 ? 29.22722 -19.04816 40.33648  1.000 64.15101  ? 392 ALA   A CA  1 
ATOM   2879 C  C   . ALA   A 1 392 ? 28.33011 -18.95839 39.09987  1.000 65.91599  ? 392 ALA   A C   1 
ATOM   2880 O  O   . ALA   A 1 392 ? 28.78841 -18.99338 37.95555  1.000 68.78886  ? 392 ALA   A O   1 
ATOM   2881 C  CB  . ALA   A 1 392 ? 30.70980 -19.05313 39.94770  1.000 64.60395  ? 392 ALA   A CB  1 
ATOM   2882 N  N   . CYS   A 1 393 ? 27.02981 -18.83451 39.35548  1.000 65.52428  ? 393 CYS   A N   1 
ATOM   2883 C  CA  . CYS   A 1 393 ? 26.04855 -18.74691 38.28403  1.000 64.30520  ? 393 CYS   A CA  1 
ATOM   2884 C  C   . CYS   A 1 393 ? 24.74477 -18.20362 38.84713  1.000 64.49351  ? 393 CYS   A C   1 
ATOM   2885 O  O   . CYS   A 1 393 ? 24.47697 -18.29617 40.04816  1.000 64.35025  ? 393 CYS   A O   1 
ATOM   2886 C  CB  . CYS   A 1 393 ? 25.81609 -20.10863 37.62161  1.000 64.27724  ? 393 CYS   A CB  1 
ATOM   2887 S  SG  . CYS   A 1 393 ? 25.05708 -21.33869 38.70556  1.000 71.63961  ? 393 CYS   A SG  1 
ATOM   2888 N  N   . LYS   A 1 394 ? 23.93684 -17.63587 37.95696  1.000 66.45240  ? 394 LYS   A N   1 
ATOM   2889 C  CA  . LYS   A 1 394 ? 22.61230 -17.16396 38.32614  1.000 65.07853  ? 394 LYS   A CA  1 
ATOM   2890 C  C   . LYS   A 1 394 ? 21.63375 -18.33083 38.37986  1.000 73.04114  ? 394 LYS   A C   1 
ATOM   2891 O  O   . LYS   A 1 394 ? 21.72093 -19.28006 37.59573  1.000 85.48310  ? 394 LYS   A O   1 
ATOM   2892 C  CB  . LYS   A 1 394 ? 22.11553 -16.11438 37.32982  1.000 60.55754  ? 394 LYS   A CB  1 
ATOM   2893 C  CG  . LYS   A 1 394 ? 20.81208 -15.43755 37.73232  1.000 65.14840  ? 394 LYS   A CG  1 
ATOM   2894 C  CD  . LYS   A 1 394 ? 20.18297 -14.69607 36.56350  1.000 70.75996  ? 394 LYS   A CD  1 
ATOM   2895 C  CE  . LYS   A 1 394 ? 21.10717 -13.61998 36.01991  1.000 65.90451  ? 394 LYS   A CE  1 
ATOM   2896 N  NZ  . LYS   A 1 394 ? 20.50381 -12.90540 34.86092  1.000 59.68813  ? 394 LYS   A NZ  1 
ATOM   2897 N  N   . VAL   A 1 395 ? 20.69838 -18.25558 39.31934  1.000 68.42739  ? 395 VAL   A N   1 
ATOM   2898 C  CA  . VAL   A 1 395 ? 19.66333 -19.27134 39.47389  1.000 70.50030  ? 395 VAL   A CA  1 
ATOM   2899 C  C   . VAL   A 1 395 ? 18.38699 -18.88270 38.74014  1.000 78.12716  ? 395 VAL   A C   1 
ATOM   2900 O  O   . VAL   A 1 395 ? 17.83636 -19.67624 37.97664  1.000 80.23936  ? 395 VAL   A O   1 
ATOM   2901 C  CB  . VAL   A 1 395 ? 19.39128 -19.53663 40.97116  1.000 67.07015  ? 395 VAL   A CB  1 
ATOM   2902 C  CG1 . VAL   A 1 395 ? 18.31407 -20.59720 41.13506  1.000 70.33444  ? 395 VAL   A CG1 1 
ATOM   2903 C  CG2 . VAL   A 1 395 ? 20.67234 -19.95270 41.67717  1.000 70.78107  ? 395 VAL   A CG2 1 
ATOM   2904 N  N   . GLU   A 1 396 ? 17.90726 -17.65959 38.95378  1.000 78.93829  ? 396 GLU   A N   1 
ATOM   2905 C  CA  . GLU   A 1 396 ? 16.67361 -17.19859 38.33014  1.000 87.28533  ? 396 GLU   A CA  1 
ATOM   2906 C  C   . GLU   A 1 396 ? 16.56988 -15.68906 38.48666  1.000 82.31555  ? 396 GLU   A C   1 
ATOM   2907 O  O   . GLU   A 1 396 ? 17.22084 -15.08827 39.34643  1.000 75.74107  ? 396 GLU   A O   1 
ATOM   2908 C  CB  . GLU   A 1 396 ? 15.44508 -17.88191 38.94041  1.000 84.64385  ? 396 GLU   A CB  1 
ATOM   2909 C  CG  . GLU   A 1 396 ? 15.44332 -17.89674 40.46012  1.000 83.44793  ? 396 GLU   A CG  1 
ATOM   2910 C  CD  . GLU   A 1 396 ? 14.16364 -18.46675 41.03642  1.000 91.33433  ? 396 GLU   A CD  1 
ATOM   2911 O  OE1 . GLU   A 1 396 ? 13.07363 -18.06350 40.57899  1.000 90.83181  ? 396 GLU   A OE1 1 
ATOM   2912 O  OE2 . GLU   A 1 396 ? 14.24803 -19.32278 41.94246  1.000 95.43281  ? 396 GLU   A OE2 1 
ATOM   2913 N  N   . ASP   A 1 397 ? 15.74059 -15.08743 37.63856  1.000 83.88167  ? 397 ASP   A N   1 
ATOM   2914 C  CA  . ASP   A 1 397 ? 15.40101 -13.67405 37.72817  1.000 84.26814  ? 397 ASP   A CA  1 
ATOM   2915 C  C   . ASP   A 1 397 ? 14.01631 -13.54013 38.34651  1.000 80.59788  ? 397 ASP   A C   1 
ATOM   2916 O  O   . ASP   A 1 397 ? 13.07772 -14.22874 37.93262  1.000 86.48596  ? 397 ASP   A O   1 
ATOM   2917 C  CB  . ASP   A 1 397 ? 15.44082 -13.01140 36.35051  1.000 96.27852  ? 397 ASP   A CB  1 
ATOM   2918 C  CG  . ASP   A 1 397 ? 16.84640 -12.92011 35.78941  1.000 93.77877  ? 397 ASP   A CG  1 
ATOM   2919 O  OD1 . ASP   A 1 397 ? 17.76558 -12.54257 36.54614  1.000 90.17707  ? 397 ASP   A OD1 1 
ATOM   2920 O  OD2 . ASP   A 1 397 ? 17.03338 -13.23101 34.59398  1.000 88.51957  ? 397 ASP   A OD2 1 
ATOM   2921 N  N   . LEU   A 1 398 ? 13.89246 -12.65440 39.33353  1.000 76.25117  ? 398 LEU   A N   1 
ATOM   2922 C  CA  . LEU   A 1 398 ? 12.68363 -12.56312 40.14089  1.000 77.29845  ? 398 LEU   A CA  1 
ATOM   2923 C  C   . LEU   A 1 398 ? 11.78313 -11.39458 39.76142  1.000 84.40540  ? 398 LEU   A C   1 
ATOM   2924 O  O   . LEU   A 1 398 ? 10.63148 -11.35458 40.20733  1.000 82.30262  ? 398 LEU   A O   1 
ATOM   2925 C  CB  . LEU   A 1 398 ? 13.04887 -12.46106 41.62892  1.000 75.80670  ? 398 LEU   A CB  1 
ATOM   2926 C  CG  . LEU   A 1 398 ? 13.36639 -13.75010 42.39694  1.000 79.86542  ? 398 LEU   A CG  1 
ATOM   2927 C  CD1 . LEU   A 1 398 ? 14.48842 -14.55650 41.75637  1.000 83.54143  ? 398 LEU   A CD1 1 
ATOM   2928 C  CD2 . LEU   A 1 398 ? 13.71978 -13.41849 43.83159  1.000 75.08252  ? 398 LEU   A CD2 1 
ATOM   2929 N  N   . GLY   A 1 399 ? 12.26796 -10.45191 38.95880  1.000 81.41992  ? 399 GLY   A N   1 
ATOM   2930 C  CA  . GLY   A 1 399 ? 11.44760 -9.32744  38.55864  1.000 69.85574  ? 399 GLY   A CA  1 
ATOM   2931 C  C   . GLY   A 1 399 ? 11.43989 -8.21672  39.59488  1.000 70.75800  ? 399 GLY   A C   1 
ATOM   2932 O  O   . GLY   A 1 399 ? 12.31562 -8.11595  40.45912  1.000 75.37089  ? 399 GLY   A O   1 
ATOM   2933 N  N   . LYS   A 1 400 ? 10.41643 -7.36985  39.50060  1.000 78.56300  ? 400 LYS   A N   1 
ATOM   2934 C  CA  . LYS   A 1 400 ? 10.28366 -6.20934  40.38264  1.000 87.16546  ? 400 LYS   A CA  1 
ATOM   2935 C  C   . LYS   A 1 400 ? 9.56353  -6.58805  41.67902  1.000 89.55053  ? 400 LYS   A C   1 
ATOM   2936 O  O   . LYS   A 1 400 ? 8.48843  -6.08532  42.00492  1.000 96.48049  ? 400 LYS   A O   1 
ATOM   2937 C  CB  . LYS   A 1 400 ? 9.56257  -5.07743  39.65954  1.000 86.53557  ? 400 LYS   A CB  1 
ATOM   2938 C  CG  . LYS   A 1 400 ? 10.43008 -4.31173  38.67488  1.000 84.26655  ? 400 LYS   A CG  1 
ATOM   2939 C  CD  . LYS   A 1 400 ? 9.64105  -3.20452  37.99422  1.000 93.83226  ? 400 LYS   A CD  1 
ATOM   2940 C  CE  . LYS   A 1 400 ? 10.55882 -2.24347  37.25546  1.000 99.37531  ? 400 LYS   A CE  1 
ATOM   2941 N  NZ  . LYS   A 1 400 ? 11.42301 -2.94154  36.26479  1.000 93.28281  ? 400 LYS   A NZ  1 
ATOM   2942 N  N   . VAL   A 1 401 ? 10.18804 -7.49121  42.42777  1.000 84.39567  ? 401 VAL   A N   1 
ATOM   2943 C  CA  . VAL   A 1 401 ? 9.66707  -7.90244  43.72240  1.000 79.46443  ? 401 VAL   A CA  1 
ATOM   2944 C  C   . VAL   A 1 401 ? 10.33832 -7.07766  44.81366  1.000 77.89400  ? 401 VAL   A C   1 
ATOM   2945 O  O   . VAL   A 1 401 ? 11.37027 -6.43596  44.60021  1.000 71.74207  ? 401 VAL   A O   1 
ATOM   2946 C  CB  . VAL   A 1 401 ? 9.86631  -9.41261  43.96424  1.000 76.70101  ? 401 VAL   A CB  1 
ATOM   2947 C  CG1 . VAL   A 1 401 ? 9.12862  -10.22033 42.90843  1.000 76.31270  ? 401 VAL   A CG1 1 
ATOM   2948 C  CG2 . VAL   A 1 401 ? 11.34645 -9.75984  43.97246  1.000 77.27662  ? 401 VAL   A CG2 1 
ATOM   2949 N  N   . ASP   A 1 402 ? 9.73806  -7.09004  46.00148  1.000 80.78213  ? 402 ASP   A N   1 
ATOM   2950 C  CA  . ASP   A 1 402 ? 10.30075 -6.36017  47.12935  1.000 79.84097  ? 402 ASP   A CA  1 
ATOM   2951 C  C   . ASP   A 1 402 ? 11.58158 -7.04068  47.59580  1.000 77.05476  ? 402 ASP   A C   1 
ATOM   2952 O  O   . ASP   A 1 402 ? 11.61747 -8.26083  47.78083  1.000 75.40513  ? 402 ASP   A O   1 
ATOM   2953 C  CB  . ASP   A 1 402 ? 9.28638  -6.27999  48.26959  1.000 80.67752  ? 402 ASP   A CB  1 
ATOM   2954 C  CG  . ASP   A 1 402 ? 9.60634  -5.17607  49.26309  1.000 88.15342  ? 402 ASP   A CG  1 
ATOM   2955 O  OD1 . ASP   A 1 402 ? 10.80078 -4.95121  49.55122  1.000 88.57582  ? 402 ASP   A OD1 1 
ATOM   2956 O  OD2 . ASP   A 1 402 ? 8.65860  -4.52765  49.75463  1.000 91.34966  ? 402 ASP   A OD2 1 
ATOM   2957 N  N   . PHE   A 1 403 ? 12.63600 -6.24582  47.78757  1.000 81.22582  ? 403 PHE   A N   1 
ATOM   2958 C  CA  . PHE   A 1 403 ? 13.94435 -6.81496  48.09406  1.000 80.84638  ? 403 PHE   A CA  1 
ATOM   2959 C  C   . PHE   A 1 403 ? 13.99357 -7.35745  49.51774  1.000 77.81809  ? 403 PHE   A C   1 
ATOM   2960 O  O   . PHE   A 1 403 ? 14.41180 -8.49861  49.74129  1.000 76.55482  ? 403 PHE   A O   1 
ATOM   2961 C  CB  . PHE   A 1 403 ? 15.03545 -5.76718  47.87113  1.000 82.73391  ? 403 PHE   A CB  1 
ATOM   2962 C  CG  . PHE   A 1 403 ? 16.42214 -6.34082  47.80746  1.000 83.18232  ? 403 PHE   A CG  1 
ATOM   2963 C  CD1 . PHE   A 1 403 ? 16.77226 -7.22748  46.80190  1.000 77.81419  ? 403 PHE   A CD1 1 
ATOM   2964 C  CD2 . PHE   A 1 403 ? 17.37854 -5.98611  48.74411  1.000 85.55651  ? 403 PHE   A CD2 1 
ATOM   2965 C  CE1 . PHE   A 1 403 ? 18.04752 -7.75705  46.73703  1.000 76.01379  ? 403 PHE   A CE1 1 
ATOM   2966 C  CE2 . PHE   A 1 403 ? 18.65670 -6.51067  48.68288  1.000 85.72721  ? 403 PHE   A CE2 1 
ATOM   2967 C  CZ  . PHE   A 1 403 ? 18.99080 -7.39748  47.67834  1.000 78.88622  ? 403 PHE   A CZ  1 
ATOM   2968 N  N   . GLU   A 1 404 ? 13.56684 -6.55533  50.49619  1.000 78.28689  ? 404 GLU   A N   1 
ATOM   2969 C  CA  . GLU   A 1 404 ? 13.60212 -7.00733  51.88436  1.000 76.53957  ? 404 GLU   A CA  1 
ATOM   2970 C  C   . GLU   A 1 404 ? 12.59402 -8.12408  52.12740  1.000 80.87095  ? 404 GLU   A C   1 
ATOM   2971 O  O   . GLU   A 1 404 ? 12.87447 -9.07292  52.87202  1.000 79.67778  ? 404 GLU   A O   1 
ATOM   2972 C  CB  . GLU   A 1 404 ? 13.34005 -5.83404  52.82923  1.000 77.88373  ? 404 GLU   A CB  1 
ATOM   2973 C  CG  . GLU   A 1 404 ? 14.17100 -4.59343  52.53520  1.000 91.01538  ? 404 GLU   A CG  1 
ATOM   2974 C  CD  . GLU   A 1 404 ? 13.50341 -3.66567  51.53647  1.000 96.60347  ? 404 GLU   A CD  1 
ATOM   2975 O  OE1 . GLU   A 1 404 ? 12.26289 -3.52837  51.58931  1.000 95.87641  ? 404 GLU   A OE1 1 
ATOM   2976 O  OE2 . GLU   A 1 404 ? 14.21732 -3.07892  50.69588  1.000 92.25372  ? 404 GLU   A OE2 1 
ATOM   2977 N  N   . ASP   A 1 405 ? 11.41447 -8.02748  51.50851  1.000 86.74550  ? 405 ASP   A N   1 
ATOM   2978 C  CA  . ASP   A 1 405 ? 10.41630 -9.08129  51.65308  1.000 84.11427  ? 405 ASP   A CA  1 
ATOM   2979 C  C   . ASP   A 1 405 ? 10.91580 -10.39427 51.06611  1.000 84.38552  ? 405 ASP   A C   1 
ATOM   2980 O  O   . ASP   A 1 405 ? 10.64801 -11.46808 51.61451  1.000 88.01407  ? 405 ASP   A O   1 
ATOM   2981 C  CB  . ASP   A 1 405 ? 9.10502  -8.66038  50.99004  1.000 88.37519  ? 405 ASP   A CB  1 
ATOM   2982 C  CG  . ASP   A 1 405 ? 8.51173  -7.41194  51.61241  1.000 105.33171 ? 405 ASP   A CG  1 
ATOM   2983 O  OD1 . ASP   A 1 405 ? 9.09265  -6.90027  52.59282  1.000 106.98201 ? 405 ASP   A OD1 1 
ATOM   2984 O  OD2 . ASP   A 1 405 ? 7.46448  -6.94131  51.12041  1.000 111.35533 ? 405 ASP   A OD2 1 
ATOM   2985 N  N   . GLU   A 1 406 ? 11.65528 -10.33007 49.95621  1.000 79.58353  ? 406 GLU   A N   1 
ATOM   2986 C  CA  . GLU   A 1 406 ? 12.20223 -11.54976 49.37197  1.000 73.20239  ? 406 GLU   A CA  1 
ATOM   2987 C  C   . GLU   A 1 406 ? 13.38030 -12.07895 50.18028  1.000 75.48980  ? 406 GLU   A C   1 
ATOM   2988 O  O   . GLU   A 1 406 ? 13.58217 -13.29689 50.25254  1.000 75.67762  ? 406 GLU   A O   1 
ATOM   2989 C  CB  . GLU   A 1 406 ? 12.61977 -11.30041 47.92385  1.000 68.10457  ? 406 GLU   A CB  1 
ATOM   2990 C  CG  . GLU   A 1 406 ? 12.98511 -12.56087 47.16338  1.000 70.27404  ? 406 GLU   A CG  1 
ATOM   2991 C  CD  . GLU   A 1 406 ? 11.77691 -13.41248 46.82307  1.000 76.71478  ? 406 GLU   A CD  1 
ATOM   2992 O  OE1 . GLU   A 1 406 ? 10.64568 -12.88307 46.85061  1.000 81.30156  ? 406 GLU   A OE1 1 
ATOM   2993 O  OE2 . GLU   A 1 406 ? 11.95839 -14.61223 46.52654  1.000 70.44379  ? 406 GLU   A OE2 1 
ATOM   2994 N  N   . ILE   A 1 407 ? 14.16872 -11.18553 50.78371  1.000 77.96621  ? 407 ILE   A N   1 
ATOM   2995 C  CA  . ILE   A 1 407 ? 15.24214 -11.61577 51.67720  1.000 81.33804  ? 407 ILE   A CA  1 
ATOM   2996 C  C   . ILE   A 1 407 ? 14.66607 -12.39216 52.85326  1.000 85.70300  ? 407 ILE   A C   1 
ATOM   2997 O  O   . ILE   A 1 407 ? 15.13658 -13.48361 53.19485  1.000 90.14453  ? 407 ILE   A O   1 
ATOM   2998 C  CB  . ILE   A 1 407 ? 16.06365 -10.40433 52.15400  1.000 80.57805  ? 407 ILE   A CB  1 
ATOM   2999 C  CG1 . ILE   A 1 407 ? 16.95134 -9.87553  51.02650  1.000 81.68984  ? 407 ILE   A CG1 1 
ATOM   3000 C  CG2 . ILE   A 1 407 ? 16.89708 -10.76955 53.37495  1.000 78.23604  ? 407 ILE   A CG2 1 
ATOM   3001 C  CD1 . ILE   A 1 407 ? 17.66179 -8.58879  51.37391  1.000 87.50232  ? 407 ILE   A CD1 1 
ATOM   3002 N  N   . LYS   A 1 408 ? 13.63356 -11.83796 53.48963  1.000 82.47014  ? 408 LYS   A N   1 
ATOM   3003 C  CA  . LYS   A 1 408 ? 12.97762 -12.53568 54.58912  1.000 79.69531  ? 408 LYS   A CA  1 
ATOM   3004 C  C   . LYS   A 1 408 ? 12.14230 -13.71496 54.10887  1.000 82.46499  ? 408 LYS   A C   1 
ATOM   3005 O  O   . LYS   A 1 408 ? 11.76596 -14.56437 54.92303  1.000 82.50738  ? 408 LYS   A O   1 
ATOM   3006 C  CB  . LYS   A 1 408 ? 12.10777 -11.55783 55.37858  1.000 83.06444  ? 408 LYS   A CB  1 
ATOM   3007 C  CG  . LYS   A 1 408 ? 12.85614 -10.31874 55.84084  1.000 92.21067  ? 408 LYS   A CG  1 
ATOM   3008 C  CD  . LYS   A 1 408 ? 11.90073 -9.20493  56.22736  1.000 89.89959  ? 408 LYS   A CD  1 
ATOM   3009 C  CE  . LYS   A 1 408 ? 12.64097 -7.88908  56.40777  1.000 86.81537  ? 408 LYS   A CE  1 
ATOM   3010 N  NZ  . LYS   A 1 408 ? 11.70874 -6.75909  56.67645  1.000 99.05195  ? 408 LYS   A NZ  1 
ATOM   3011 N  N   . LYS   A 1 409 ? 11.85163 -13.78598 52.80923  1.000 84.02887  ? 409 LYS   A N   1 
ATOM   3012 C  CA  . LYS   A 1 409 ? 11.07037 -14.88780 52.26199  1.000 85.54761  ? 409 LYS   A CA  1 
ATOM   3013 C  C   . LYS   A 1 409 ? 11.91266 -16.14254 52.07230  1.000 87.24745  ? 409 LYS   A C   1 
ATOM   3014 O  O   . LYS   A 1 409 ? 11.38755 -17.25750 52.17087  1.000 90.79206  ? 409 LYS   A O   1 
ATOM   3015 C  CB  . LYS   A 1 409 ? 10.43952 -14.46295 50.93333  1.000 85.81816  ? 409 LYS   A CB  1 
ATOM   3016 C  CG  . LYS   A 1 409 ? 9.26954  -15.31724 50.47729  1.000 97.31778  ? 409 LYS   A CG  1 
ATOM   3017 C  CD  . LYS   A 1 409 ? 8.58378  -14.68960 49.27265  1.000 103.59514 ? 409 LYS   A CD  1 
ATOM   3018 C  CE  . LYS   A 1 409 ? 7.32970  -15.45226 48.88186  1.000 100.15944 ? 409 LYS   A CE  1 
ATOM   3019 N  NZ  . LYS   A 1 409 ? 6.61642  -14.79553 47.75118  1.000 86.17202  ? 409 LYS   A NZ  1 
ATOM   3020 N  N   . ARG   A 1 410 ? 13.20661 -15.98497 51.80043  1.000 85.55811  ? 410 ARG   A N   1 
ATOM   3021 C  CA  . ARG   A 1 410 ? 14.13855 -17.10764 51.70481  1.000 85.52477  ? 410 ARG   A CA  1 
ATOM   3022 C  C   . ARG   A 1 410 ? 14.96975 -17.10742 52.98339  1.000 79.29673  ? 410 ARG   A C   1 
ATOM   3023 O  O   . ARG   A 1 410 ? 16.05342 -16.52622 53.04531  1.000 76.18914  ? 410 ARG   A O   1 
ATOM   3024 C  CB  . ARG   A 1 410 ? 15.00654 -16.99708 50.45689  1.000 80.66761  ? 410 ARG   A CB  1 
ATOM   3025 C  CG  . ARG   A 1 410 ? 14.21684 -16.78575 49.17646  1.000 76.52588  ? 410 ARG   A CG  1 
ATOM   3026 C  CD  . ARG   A 1 410 ? 14.83983 -17.53638 48.01235  1.000 82.59139  ? 410 ARG   A CD  1 
ATOM   3027 N  NE  . ARG   A 1 410 ? 14.10512 -17.32178 46.77154  1.000 84.29498  ? 410 ARG   A NE  1 
ATOM   3028 C  CZ  . ARG   A 1 410 ? 14.25336 -18.05546 45.67708  1.000 86.13238  ? 410 ARG   A CZ  1 
ATOM   3029 N  NH1 . ARG   A 1 410 ? 15.09171 -19.07834 45.63894  1.000 86.27166  ? 410 ARG   A NH1 1 
ATOM   3030 N  NH2 . ARG   A 1 410 ? 13.53881 -17.75864 44.59529  1.000 82.02061  ? 410 ARG   A NH2 1 
ATOM   3031 N  N   . PHE   A 1 411 ? 14.44819 -17.76521 54.01455  1.000 75.17147  ? 411 PHE   A N   1 
ATOM   3032 C  CA  . PHE   A 1 411 ? 15.05118 -17.76828 55.34503  1.000 79.36838  ? 411 PHE   A CA  1 
ATOM   3033 C  C   . PHE   A 1 411 ? 15.39130 -19.20688 55.72176  1.000 88.59385  ? 411 PHE   A C   1 
ATOM   3034 O  O   . PHE   A 1 411 ? 14.50650 -19.98627 56.08998  1.000 95.65616  ? 411 PHE   A O   1 
ATOM   3035 C  CB  . PHE   A 1 411 ? 14.11073 -17.13087 56.36445  1.000 88.49350  ? 411 PHE   A CB  1 
ATOM   3036 C  CG  . PHE   A 1 411 ? 14.69736 -17.01241 57.74215  1.000 98.94289  ? 411 PHE   A CG  1 
ATOM   3037 C  CD1 . PHE   A 1 411 ? 15.47093 -15.91644 58.08838  1.000 101.01090 ? 411 PHE   A CD1 1 
ATOM   3038 C  CD2 . PHE   A 1 411 ? 14.46863 -17.99238 58.69408  1.000 94.52201  ? 411 PHE   A CD2 1 
ATOM   3039 C  CE1 . PHE   A 1 411 ? 16.00981 -15.80313 59.35667  1.000 100.72063 ? 411 PHE   A CE1 1 
ATOM   3040 C  CE2 . PHE   A 1 411 ? 15.00466 -17.88502 59.96284  1.000 99.24851  ? 411 PHE   A CE2 1 
ATOM   3041 C  CZ  . PHE   A 1 411 ? 15.77587 -16.78898 60.29469  1.000 105.29783 ? 411 PHE   A CZ  1 
ATOM   3042 N  N   . LYS   A 1 412 ? 16.67229 -19.55311 55.63253  1.000 97.22462  ? 412 LYS   A N   1 
ATOM   3043 C  CA  . LYS   A 1 412 ? 17.17333 -20.86144 56.03078  1.000 105.10586 ? 412 LYS   A CA  1 
ATOM   3044 C  C   . LYS   A 1 412 ? 17.91306 -20.72204 57.35509  1.000 96.94346  ? 412 LYS   A C   1 
ATOM   3045 O  O   . LYS   A 1 412 ? 18.75010 -19.82680 57.51258  1.000 93.66177  ? 412 LYS   A O   1 
ATOM   3046 C  CB  . LYS   A 1 412 ? 18.08619 -21.44712 54.95095  1.000 103.93302 ? 412 LYS   A CB  1 
ATOM   3047 C  CG  . LYS   A 1 412 ? 17.40512 -21.58447 53.59353  1.000 106.56451 ? 412 LYS   A CG  1 
ATOM   3048 C  CD  . LYS   A 1 412 ? 18.36907 -22.04291 52.50915  1.000 105.94595 ? 412 LYS   A CD  1 
ATOM   3049 C  CE  . LYS   A 1 412 ? 18.82071 -23.47807 52.72603  1.000 104.81652 ? 412 LYS   A CE  1 
ATOM   3050 N  NZ  . LYS   A 1 412 ? 19.69416 -23.95149 51.61503  1.000 102.32722 ? 412 LYS   A NZ  1 
ATOM   3051 N  N   . MET   A 1 413 ? 17.60140 -21.60829 58.30340  1.000 93.19732  ? 413 MET   A N   1 
ATOM   3052 C  CA  . MET   A 1 413 ? 18.06206 -21.43219 59.67702  1.000 88.90064  ? 413 MET   A CA  1 
ATOM   3053 C  C   . MET   A 1 413 ? 19.51494 -21.85299 59.87350  1.000 90.92047  ? 413 MET   A C   1 
ATOM   3054 O  O   . MET   A 1 413 ? 20.17453 -21.35807 60.79354  1.000 95.30357  ? 413 MET   A O   1 
ATOM   3055 C  CB  . MET   A 1 413 ? 17.15291 -22.21232 60.63172  1.000 90.58912  ? 413 MET   A CB  1 
ATOM   3056 C  CG  . MET   A 1 413 ? 17.49273 -22.05012 62.10761  1.000 100.70591 ? 413 MET   A CG  1 
ATOM   3057 S  SD  . MET   A 1 413 ? 16.31252 -22.85759 63.20586  1.000 109.23840 ? 413 MET   A SD  1 
ATOM   3058 C  CE  . MET   A 1 413 ? 14.86953 -21.82408 62.96812  1.000 98.80234  ? 413 MET   A CE  1 
ATOM   3059 N  N   . VAL   A 1 414 ? 20.03454 -22.74902 59.03122  1.000 90.14088  ? 414 VAL   A N   1 
ATOM   3060 C  CA  . VAL   A 1 414 ? 21.38302 -23.26338 59.24114  1.000 88.72927  ? 414 VAL   A CA  1 
ATOM   3061 C  C   . VAL   A 1 414 ? 22.40113 -22.13151 59.16364  1.000 80.02632  ? 414 VAL   A C   1 
ATOM   3062 O  O   . VAL   A 1 414 ? 22.33506 -21.26196 58.28465  1.000 86.92808  ? 414 VAL   A O   1 
ATOM   3063 C  CB  . VAL   A 1 414 ? 21.69681 -24.37284 58.22348  1.000 105.62587 ? 414 VAL   A CB  1 
ATOM   3064 C  CG1 . VAL   A 1 414 ? 20.92141 -25.63606 58.56670  1.000 101.25854 ? 414 VAL   A CG1 1 
ATOM   3065 C  CG2 . VAL   A 1 414 ? 21.36373 -23.91274 56.81179  1.000 102.40269 ? 414 VAL   A CG2 1 
ATOM   3066 N  N   . TYR   A 1 415 ? 23.34512 -22.13274 60.10340  1.000 67.44516  ? 415 TYR   A N   1 
ATOM   3067 C  CA  . TYR   A 1 415 ? 24.38254 -21.11222 60.16539  1.000 64.31434  ? 415 TYR   A CA  1 
ATOM   3068 C  C   . TYR   A 1 415 ? 25.63666 -21.57270 59.43720  1.000 72.74949  ? 415 TYR   A C   1 
ATOM   3069 O  O   . TYR   A 1 415 ? 26.06640 -22.72176 59.57421  1.000 74.69118  ? 415 TYR   A O   1 
ATOM   3070 C  CB  . TYR   A 1 415 ? 24.72942 -20.77128 61.61617  1.000 63.04820  ? 415 TYR   A CB  1 
ATOM   3071 C  CG  . TYR   A 1 415 ? 26.11838 -20.19559 61.79714  1.000 68.68352  ? 415 TYR   A CG  1 
ATOM   3072 C  CD1 . TYR   A 1 415 ? 26.39094 -18.87132 61.47936  1.000 77.19406  ? 415 TYR   A CD1 1 
ATOM   3073 C  CD2 . TYR   A 1 415 ? 27.15674 -20.97708 62.28980  1.000 66.68696  ? 415 TYR   A CD2 1 
ATOM   3074 C  CE1 . TYR   A 1 415 ? 27.65950 -18.34297 61.64301  1.000 70.90668  ? 415 TYR   A CE1 1 
ATOM   3075 C  CE2 . TYR   A 1 415 ? 28.42665 -20.45748 62.45548  1.000 58.88948  ? 415 TYR   A CE2 1 
ATOM   3076 C  CZ  . TYR   A 1 415 ? 28.67255 -19.14090 62.13175  1.000 61.69922  ? 415 TYR   A CZ  1 
ATOM   3077 O  OH  . TYR   A 1 415 ? 29.93593 -18.62109 62.29718  1.000 60.11708  ? 415 TYR   A OH  1 
ATOM   3078 N  N   . VAL   A 1 416 ? 26.22018 -20.66220 58.66480  1.000 72.94316  ? 416 VAL   A N   1 
ATOM   3079 C  CA  . VAL   A 1 416 ? 27.48476 -20.89635 57.97277  1.000 64.82534  ? 416 VAL   A CA  1 
ATOM   3080 C  C   . VAL   A 1 416 ? 28.35356 -19.66116 58.18439  1.000 60.60498  ? 416 VAL   A C   1 
ATOM   3081 O  O   . VAL   A 1 416 ? 27.83680 -18.53501 58.15990  1.000 60.75811  ? 416 VAL   A O   1 
ATOM   3082 C  CB  . VAL   A 1 416 ? 27.26055 -21.19468 56.48001  1.000 60.99626  ? 416 VAL   A CB  1 
ATOM   3083 C  CG1 . VAL   A 1 416 ? 28.58584 -21.31789 55.74371  1.000 57.69644  ? 416 VAL   A CG1 1 
ATOM   3084 C  CG2 . VAL   A 1 416 ? 26.44140 -22.46818 56.30534  1.000 66.81861  ? 416 VAL   A CG2 1 
ATOM   3085 N  N   . PRO   A 1 417 ? 29.65154 -19.81246 58.43370  1.000 55.57837  ? 417 PRO   A N   1 
ATOM   3086 C  CA  . PRO   A 1 417 ? 30.50790 -18.63505 58.60910  1.000 61.39012  ? 417 PRO   A CA  1 
ATOM   3087 C  C   . PRO   A 1 417 ? 30.73199 -17.89587 57.29761  1.000 66.97561  ? 417 PRO   A C   1 
ATOM   3088 O  O   . PRO   A 1 417 ? 30.56847 -18.43819 56.20229  1.000 68.15060  ? 417 PRO   A O   1 
ATOM   3089 C  CB  . PRO   A 1 417 ? 31.82103 -19.22214 59.14081  1.000 62.67283  ? 417 PRO   A CB  1 
ATOM   3090 C  CG  . PRO   A 1 417 ? 31.45500 -20.57096 59.67656  1.000 60.76795  ? 417 PRO   A CG  1 
ATOM   3091 C  CD  . PRO   A 1 417 ? 30.34671 -21.05754 58.79858  1.000 59.91551  ? 417 PRO   A CD  1 
ATOM   3092 N  N   . ASN   A 1 418 ? 31.11190 -16.62624 57.42943  1.000 74.83962  ? 418 ASN   A N   1 
ATOM   3093 C  CA  . ASN   A 1 418 ? 31.47451 -15.82404 56.26847  1.000 70.11296  ? 418 ASN   A CA  1 
ATOM   3094 C  C   . ASN   A 1 418 ? 32.83774 -16.25508 55.74504  1.000 72.15480  ? 418 ASN   A C   1 
ATOM   3095 O  O   . ASN   A 1 418 ? 33.82094 -16.27982 56.49143  1.000 77.62411  ? 418 ASN   A O   1 
ATOM   3096 C  CB  . ASN   A 1 418 ? 31.49081 -14.33968 56.62982  1.000 73.66062  ? 418 ASN   A CB  1 
ATOM   3097 C  CG  . ASN   A 1 418 ? 30.10799 -13.72384 56.62450  1.000 90.98650  ? 418 ASN   A CG  1 
ATOM   3098 O  OD1 . ASN   A 1 418 ? 29.27909 -14.04120 55.77292  1.000 92.55888  ? 418 ASN   A OD1 1 
ATOM   3099 N  ND2 . ASN   A 1 418 ? 29.85201 -12.83438 57.57730  1.000 97.86865  ? 418 ASN   A ND2 1 
ATOM   3100 N  N   . TRP   A 1 419 ? 32.89799 -16.59430 54.45555  1.000 68.84306  ? 419 TRP   A N   1 
ATOM   3101 C  CA  . TRP   A 1 419 ? 34.12706 -17.09392 53.85352  1.000 69.92108  ? 419 TRP   A CA  1 
ATOM   3102 C  C   . TRP   A 1 419 ? 34.53606 -16.32379 52.60320  1.000 71.74186  ? 419 TRP   A C   1 
ATOM   3103 O  O   . TRP   A 1 419 ? 35.46887 -16.74726 51.90973  1.000 74.34866  ? 419 TRP   A O   1 
ATOM   3104 C  CB  . TRP   A 1 419 ? 33.99410 -18.58676 53.52455  1.000 64.58302  ? 419 TRP   A CB  1 
ATOM   3105 C  CG  . TRP   A 1 419 ? 32.83213 -18.91296 52.63377  1.000 64.99969  ? 419 TRP   A CG  1 
ATOM   3106 C  CD1 . TRP   A 1 419 ? 31.51570 -18.96653 52.99032  1.000 64.39218  ? 419 TRP   A CD1 1 
ATOM   3107 C  CD2 . TRP   A 1 419 ? 32.88322 -19.24333 51.24021  1.000 68.06259  ? 419 TRP   A CD2 1 
ATOM   3108 N  NE1 . TRP   A 1 419 ? 30.74396 -19.30297 51.90514  1.000 64.79810  ? 419 TRP   A NE1 1 
ATOM   3109 C  CE2 . TRP   A 1 419 ? 31.55933 -19.47948 50.81848  1.000 67.59793  ? 419 TRP   A CE2 1 
ATOM   3110 C  CE3 . TRP   A 1 419 ? 33.91886 -19.35977 50.30798  1.000 72.02789  ? 419 TRP   A CE3 1 
ATOM   3111 C  CZ2 . TRP   A 1 419 ? 31.24393 -19.82385 49.50592  1.000 67.21852  ? 419 TRP   A CZ2 1 
ATOM   3112 C  CZ3 . TRP   A 1 419 ? 33.60325 -19.70244 49.00503  1.000 70.69692  ? 419 TRP   A CZ3 1 
ATOM   3113 C  CH2 . TRP   A 1 419 ? 32.27708 -19.93036 48.61654  1.000 66.79599  ? 419 TRP   A CH2 1 
ATOM   3114 N  N   . PHE   A 1 420 ? 33.88074 -15.20807 52.30227  1.000 65.07792  ? 420 PHE   A N   1 
ATOM   3115 C  CA  . PHE   A 1 420 ? 34.17687 -14.43937 51.09955  1.000 62.61774  ? 420 PHE   A CA  1 
ATOM   3116 C  C   . PHE   A 1 420 ? 33.62599 -13.02995 51.28128  1.000 67.67123  ? 420 PHE   A C   1 
ATOM   3117 O  O   . PHE   A 1 420 ? 33.14556 -12.66509 52.35975  1.000 69.81018  ? 420 PHE   A O   1 
ATOM   3118 C  CB  . PHE   A 1 420 ? 33.59163 -15.11977 49.85722  1.000 62.12587  ? 420 PHE   A CB  1 
ATOM   3119 C  CG  . PHE   A 1 420 ? 32.08950 -15.15767 49.83761  1.000 63.51075  ? 420 PHE   A CG  1 
ATOM   3120 C  CD1 . PHE   A 1 420 ? 31.39804 -16.13193 50.53837  1.000 67.21399  ? 420 PHE   A CD1 1 
ATOM   3121 C  CD2 . PHE   A 1 420 ? 31.36882 -14.22114 49.11499  1.000 61.46449  ? 420 PHE   A CD2 1 
ATOM   3122 C  CE1 . PHE   A 1 420 ? 30.01723 -16.16952 50.52243  1.000 66.97205  ? 420 PHE   A CE1 1 
ATOM   3123 C  CE2 . PHE   A 1 420 ? 29.98761 -14.25345 49.09483  1.000 63.48123  ? 420 PHE   A CE2 1 
ATOM   3124 C  CZ  . PHE   A 1 420 ? 29.31106 -15.22928 49.79934  1.000 64.11902  ? 420 PHE   A CZ  1 
ATOM   3125 N  N   . SER   A 1 421 ? 33.69730 -12.23503 50.21623  1.000 68.47378  ? 421 SER   A N   1 
ATOM   3126 C  CA  . SER   A 1 421 ? 33.12393 -10.89912 50.19689  1.000 60.93701  ? 421 SER   A CA  1 
ATOM   3127 C  C   . SER   A 1 421 ? 32.58844 -10.61359 48.80232  1.000 63.66274  ? 421 SER   A C   1 
ATOM   3128 O  O   . SER   A 1 421 ? 33.06720 -11.16975 47.81072  1.000 67.34664  ? 421 SER   A O   1 
ATOM   3129 C  CB  . SER   A 1 421 ? 34.15077 -9.83254  50.60082  1.000 57.64807  ? 421 SER   A CB  1 
ATOM   3130 O  OG  . SER   A 1 421 ? 35.26213 -9.83956  49.72248  1.000 63.77807  ? 421 SER   A OG  1 
ATOM   3131 N  N   . VAL   A 1 422 ? 31.58317 -9.74883  48.73631  1.000 59.29018  ? 422 VAL   A N   1 
ATOM   3132 C  CA  . VAL   A 1 422 ? 30.96822 -9.35086  47.47557  1.000 61.56985  ? 422 VAL   A CA  1 
ATOM   3133 C  C   . VAL   A 1 422 ? 31.44901 -7.95048  47.12430  1.000 64.03214  ? 422 VAL   A C   1 
ATOM   3134 O  O   . VAL   A 1 422 ? 31.64963 -7.10864  48.00938  1.000 69.01215  ? 422 VAL   A O   1 
ATOM   3135 C  CB  . VAL   A 1 422 ? 29.42935 -9.42054  47.56174  1.000 60.00867  ? 422 VAL   A CB  1 
ATOM   3136 C  CG1 . VAL   A 1 422 ? 28.90126 -8.49166  48.64867  1.000 64.51527  ? 422 VAL   A CG1 1 
ATOM   3137 C  CG2 . VAL   A 1 422 ? 28.79306 -9.10470  46.21294  1.000 63.12398  ? 422 VAL   A CG2 1 
ATOM   3138 N  N   . ASP   A 1 423 ? 31.64997 -7.70102  45.83170  1.000 61.63904  ? 423 ASP   A N   1 
ATOM   3139 C  CA  . ASP   A 1 423 ? 32.15710 -6.42451  45.35884  1.000 64.56476  ? 423 ASP   A CA  1 
ATOM   3140 C  C   . ASP   A 1 423 ? 31.36345 -5.98620  44.13844  1.000 69.67824  ? 423 ASP   A C   1 
ATOM   3141 O  O   . ASP   A 1 423 ? 31.03782 -6.80122  43.26596  1.000 75.40701  ? 423 ASP   A O   1 
ATOM   3142 C  CB  . ASP   A 1 423 ? 33.65670 -6.51724  45.02773  1.000 63.34506  ? 423 ASP   A CB  1 
ATOM   3143 C  CG  . ASP   A 1 423 ? 34.19470 -5.26000  44.36673  1.000 71.32837  ? 423 ASP   A CG  1 
ATOM   3144 O  OD1 . ASP   A 1 423 ? 33.91008 -5.04370  43.17061  1.000 70.93186  ? 423 ASP   A OD1 1 
ATOM   3145 O  OD2 . ASP   A 1 423 ? 34.90296 -4.48585  45.04497  1.000 71.47302  ? 423 ASP   A OD2 1 
ATOM   3146 N  N   . LEU   A 1 424 ? 31.06215 -4.68645  44.09069  1.000 66.61190  ? 424 LEU   A N   1 
ATOM   3147 C  CA  . LEU   A 1 424 ? 30.32048 -4.06764  43.00003  1.000 64.06389  ? 424 LEU   A CA  1 
ATOM   3148 C  C   . LEU   A 1 424 ? 31.06215 -2.85034  42.45888  1.000 67.97230  ? 424 LEU   A C   1 
ATOM   3149 O  O   . LEU   A 1 424 ? 30.43770 -1.89434  41.99099  1.000 54.59158  ? 424 LEU   A O   1 
ATOM   3150 C  CB  . LEU   A 1 424 ? 28.91322 -3.67728  43.45207  1.000 55.87689  ? 424 LEU   A CB  1 
ATOM   3151 C  CG  . LEU   A 1 424 ? 28.08810 -4.76904  44.13727  1.000 55.33714  ? 424 LEU   A CG  1 
ATOM   3152 C  CD1 . LEU   A 1 424 ? 26.78254 -4.20300  44.67282  1.000 64.23281  ? 424 LEU   A CD1 1 
ATOM   3153 C  CD2 . LEU   A 1 424 ? 27.82342 -5.92385  43.18435  1.000 59.55670  ? 424 LEU   A CD2 1 
ATOM   3154 N  N   . LYS   A 1 425 ? 32.39748 -2.86616  42.52400  1.000 76.32849  ? 425 LYS   A N   1 
ATOM   3155 C  CA  . LYS   A 1 425 ? 33.18186 -1.75743  41.99024  1.000 73.70213  ? 425 LYS   A CA  1 
ATOM   3156 C  C   . LYS   A 1 425 ? 33.03511 -1.63162  40.48076  1.000 76.28042  ? 425 LYS   A C   1 
ATOM   3157 O  O   . LYS   A 1 425 ? 33.31053 -0.56170  39.92700  1.000 80.44852  ? 425 LYS   A O   1 
ATOM   3158 C  CB  . LYS   A 1 425 ? 34.65935 -1.92577  42.35586  1.000 76.22092  ? 425 LYS   A CB  1 
ATOM   3159 C  CG  . LYS   A 1 425 ? 35.41649 -2.90293  41.46575  1.000 78.22388  ? 425 LYS   A CG  1 
ATOM   3160 C  CD  . LYS   A 1 425 ? 36.81885 -3.16765  41.98903  1.000 80.14485  ? 425 LYS   A CD  1 
ATOM   3161 C  CE  . LYS   A 1 425 ? 37.56521 -4.14798  41.09571  1.000 77.41627  ? 425 LYS   A CE  1 
ATOM   3162 N  NZ  . LYS   A 1 425 ? 36.87084 -5.46317  41.00268  1.000 70.83859  ? 425 LYS   A NZ  1 
ATOM   3163 N  N   . THR   A 1 426 ? 32.60877 -2.69968  39.80679  1.000 79.44109  ? 426 THR   A N   1 
ATOM   3164 C  CA  . THR   A 1 426 ? 32.38144 -2.68101  38.36997  1.000 74.40737  ? 426 THR   A CA  1 
ATOM   3165 C  C   . THR   A 1 426 ? 30.91114 -2.55353  38.00046  1.000 68.37997  ? 426 THR   A C   1 
ATOM   3166 O  O   . THR   A 1 426 ? 30.60365 -2.20020  36.85744  1.000 64.88894  ? 426 THR   A O   1 
ATOM   3167 C  CB  . THR   A 1 426 ? 32.94058 -3.95750  37.72841  1.000 76.98551  ? 426 THR   A CB  1 
ATOM   3168 O  OG1 . THR   A 1 426 ? 32.21800 -5.09432  38.21807  1.000 71.57629  ? 426 THR   A OG1 1 
ATOM   3169 C  CG2 . THR   A 1 426 ? 34.41422 -4.12321  38.06629  1.000 79.60538  ? 426 THR   A CG2 1 
ATOM   3170 N  N   . GLY   A 1 427 ? 30.00314 -2.81897  38.93612  1.000 66.87466  ? 427 GLY   A N   1 
ATOM   3171 C  CA  . GLY   A 1 427 ? 28.59192 -2.91270  38.65350  1.000 63.77270  ? 427 GLY   A CA  1 
ATOM   3172 C  C   . GLY   A 1 427 ? 28.08386 -4.33313  38.52976  1.000 63.37610  ? 427 GLY   A C   1 
ATOM   3173 O  O   . GLY   A 1 427 ? 26.86900 -4.55265  38.59703  1.000 59.07415  ? 427 GLY   A O   1 
ATOM   3174 N  N   . MET   A 1 428 ? 28.98198 -5.29507  38.34828  1.000 62.74221  ? 428 MET   A N   1 
ATOM   3175 C  CA  . MET   A 1 428 ? 28.65688 -6.71137  38.31139  1.000 62.32029  ? 428 MET   A CA  1 
ATOM   3176 C  C   . MET   A 1 428 ? 29.18678 -7.38925  39.56863  1.000 65.53482  ? 428 MET   A C   1 
ATOM   3177 O  O   . MET   A 1 428 ? 29.96129 -6.81340  40.33753  1.000 68.52238  ? 428 MET   A O   1 
ATOM   3178 C  CB  . MET   A 1 428 ? 29.24106 -7.37008  37.05619  1.000 66.39809  ? 428 MET   A CB  1 
ATOM   3179 C  CG  . MET   A 1 428 ? 28.79311 -6.72558  35.75387  1.000 74.87867  ? 428 MET   A CG  1 
ATOM   3180 S  SD  . MET   A 1 428 ? 29.69003 -7.34665  34.31809  1.000 76.57504  ? 428 MET   A SD  1 
ATOM   3181 C  CE  . MET   A 1 428 ? 31.36273 -6.85083  34.72446  1.000 70.57619  ? 428 MET   A CE  1 
ATOM   3182 N  N   . LEU   A 1 429 ? 28.75787 -8.63129  39.77201  1.000 62.67225  ? 429 LEU   A N   1 
ATOM   3183 C  CA  . LEU   A 1 429 ? 29.16335 -9.38342  40.95284  1.000 59.69555  ? 429 LEU   A CA  1 
ATOM   3184 C  C   . LEU   A 1 429 ? 30.62999 -9.78092  40.84470  1.000 57.21560  ? 429 LEU   A C   1 
ATOM   3185 O  O   . LEU   A 1 429 ? 31.01930 -10.48897 39.90900  1.000 59.95252  ? 429 LEU   A O   1 
ATOM   3186 C  CB  . LEU   A 1 429 ? 28.28768 -10.62305 41.11343  1.000 60.30988  ? 429 LEU   A CB  1 
ATOM   3187 C  CG  . LEU   A 1 429 ? 26.80282 -10.37757 41.37428  1.000 62.09682  ? 429 LEU   A CG  1 
ATOM   3188 C  CD1 . LEU   A 1 429 ? 26.06008 -11.69662 41.50116  1.000 61.85689  ? 429 LEU   A CD1 1 
ATOM   3189 C  CD2 . LEU   A 1 429 ? 26.62546 -9.53362  42.62418  1.000 68.85786  ? 429 LEU   A CD2 1 
ATOM   3190 N  N   . THR   A 1 430 ? 31.44406 -9.34054  41.80471  1.000 55.80771  ? 430 THR   A N   1 
ATOM   3191 C  CA  . THR   A 1 430 ? 32.84118 -9.75085  41.89360  1.000 61.26801  ? 430 THR   A CA  1 
ATOM   3192 C  C   . THR   A 1 430 ? 33.05264 -10.37084 43.26885  1.000 62.94109  ? 430 THR   A C   1 
ATOM   3193 O  O   . THR   A 1 430 ? 33.05664 -9.66166  44.27936  1.000 65.87656  ? 430 THR   A O   1 
ATOM   3194 C  CB  . THR   A 1 430 ? 33.77932 -8.56454  41.67035  1.000 67.19157  ? 430 THR   A CB  1 
ATOM   3195 O  OG1 . THR   A 1 430 ? 33.32260 -7.79599  40.54991  1.000 61.35298  ? 430 THR   A OG1 1 
ATOM   3196 C  CG2 . THR   A 1 430 ? 35.19435 -9.05018  41.39511  1.000 70.73803  ? 430 THR   A CG2 1 
ATOM   3197 N  N   . ILE   A 1 431 ? 33.20552 -11.68772 43.31617  1.000 60.58465  ? 431 ILE   A N   1 
ATOM   3198 C  CA  . ILE   A 1 431 ? 33.38008 -12.39369 44.57909  1.000 65.09681  ? 431 ILE   A CA  1 
ATOM   3199 C  C   . ILE   A 1 431 ? 34.86570 -12.46132 44.89749  1.000 65.67374  ? 431 ILE   A C   1 
ATOM   3200 O  O   . ILE   A 1 431 ? 35.66279 -12.93584 44.08024  1.000 65.15634  ? 431 ILE   A O   1 
ATOM   3201 C  CB  . ILE   A 1 431 ? 32.76313 -13.79912 44.51543  1.000 63.86229  ? 431 ILE   A CB  1 
ATOM   3202 C  CG1 . ILE   A 1 431 ? 31.29445 -13.71592 44.09388  1.000 60.92847  ? 431 ILE   A CG1 1 
ATOM   3203 C  CG2 . ILE   A 1 431 ? 32.90798 -14.49915 45.85806  1.000 58.28060  ? 431 ILE   A CG2 1 
ATOM   3204 C  CD1 . ILE   A 1 431 ? 30.43667 -12.88831 45.02404  1.000 61.96317  ? 431 ILE   A CD1 1 
ATOM   3205 N  N   . THR   A 1 432 ? 35.23812 -11.98577 46.08312  1.000 62.28216  ? 432 THR   A N   1 
ATOM   3206 C  CA  . THR   A 1 432 ? 36.62591 -11.92297 46.51595  1.000 57.67478  ? 432 THR   A CA  1 
ATOM   3207 C  C   . THR   A 1 432 ? 36.84468 -12.86336 47.69408  1.000 61.61116  ? 432 THR   A C   1 
ATOM   3208 O  O   . THR   A 1 432 ? 35.98538 -12.98464 48.57424  1.000 64.54744  ? 432 THR   A O   1 
ATOM   3209 C  CB  . THR   A 1 432 ? 37.01337 -10.49251 46.90961  1.000 58.42044  ? 432 THR   A CB  1 
ATOM   3210 O  OG1 . THR   A 1 432 ? 36.64319 -9.58836  45.86084  1.000 71.54139  ? 432 THR   A OG1 1 
ATOM   3211 C  CG2 . THR   A 1 432 ? 38.51332 -10.38582 47.14954  1.000 62.87040  ? 432 THR   A CG2 1 
ATOM   3212 N  N   . LEU   A 1 433 ? 38.00154 -13.52352 47.70427  1.000 63.84597  ? 433 LEU   A N   1 
ATOM   3213 C  CA  . LEU   A 1 433 ? 38.38163 -14.46104 48.75126  1.000 61.38187  ? 433 LEU   A CA  1 
ATOM   3214 C  C   . LEU   A 1 433 ? 39.72880 -14.03092 49.30732  1.000 63.00086  ? 433 LEU   A C   1 
ATOM   3215 O  O   . LEU   A 1 433 ? 40.70196 -13.90487 48.55314  1.000 63.20255  ? 433 LEU   A O   1 
ATOM   3216 C  CB  . LEU   A 1 433 ? 38.45443 -15.88942 48.20574  1.000 51.93241  ? 433 LEU   A CB  1 
ATOM   3217 C  CG  . LEU   A 1 433 ? 37.17942 -16.40792 47.53990  1.000 51.78296  ? 433 LEU   A CG  1 
ATOM   3218 C  CD1 . LEU   A 1 433 ? 37.51235 -17.34506 46.39250  1.000 56.09429  ? 433 LEU   A CD1 1 
ATOM   3219 C  CD2 . LEU   A 1 433 ? 36.30037 -17.10781 48.56013  1.000 61.57874  ? 433 LEU   A CD2 1 
ATOM   3220 N  N   . ASP   A 1 434 ? 39.77744 -13.80103 50.61674  1.000 63.40996  ? 434 ASP   A N   1 
ATOM   3221 C  CA  . ASP   A 1 434 ? 40.98162 -13.38484 51.31679  1.000 68.10146  ? 434 ASP   A CA  1 
ATOM   3222 C  C   . ASP   A 1 434 ? 41.51425 -14.54222 52.15237  1.000 72.11676  ? 434 ASP   A C   1 
ATOM   3223 O  O   . ASP   A 1 434 ? 40.74726 -15.36003 52.66702  1.000 74.44118  ? 434 ASP   A O   1 
ATOM   3224 C  CB  . ASP   A 1 434 ? 40.70171 -12.17233 52.21202  1.000 66.66746  ? 434 ASP   A CB  1 
ATOM   3225 C  CG  . ASP   A 1 434 ? 41.96103 -11.40862 52.57702  1.000 76.98405  ? 434 ASP   A CG  1 
ATOM   3226 O  OD1 . ASP   A 1 434 ? 43.04723 -12.02333 52.61747  1.000 84.54058  ? 434 ASP   A OD1 1 
ATOM   3227 O  OD2 . ASP   A 1 434 ? 41.86308 -10.18805 52.82443  1.000 77.50114  ? 434 ASP   A OD2 1 
ATOM   3228 N  N   . GLU   A 1 435 ? 42.84292 -14.59023 52.29208  1.000 71.52369  ? 435 GLU   A N   1 
ATOM   3229 C  CA  . GLU   A 1 435 ? 43.49661 -15.71993 52.94952  1.000 67.63988  ? 435 GLU   A CA  1 
ATOM   3230 C  C   . GLU   A 1 435 ? 42.98844 -15.93946 54.36963  1.000 65.73177  ? 435 GLU   A C   1 
ATOM   3231 O  O   . GLU   A 1 435 ? 42.90871 -17.08549 54.82808  1.000 61.64815  ? 435 GLU   A O   1 
ATOM   3232 C  CB  . GLU   A 1 435 ? 45.01124 -15.50495 52.96263  1.000 72.75672  ? 435 GLU   A CB  1 
ATOM   3233 C  CG  . GLU   A 1 435 ? 45.78600 -16.53608 53.76943  1.000 77.71158  ? 435 GLU   A CG  1 
ATOM   3234 C  CD  . GLU   A 1 435 ? 47.27264 -16.24375 53.81914  1.000 84.06828  ? 435 GLU   A CD  1 
ATOM   3235 O  OE1 . GLU   A 1 435 ? 47.69911 -15.22095 53.24305  1.000 89.79114  ? 435 GLU   A OE1 1 
ATOM   3236 O  OE2 . GLU   A 1 435 ? 48.01507 -17.03703 54.43532  1.000 78.94972  ? 435 GLU   A OE2 1 
ATOM   3237 N  N   . SER   A 1 436 ? 42.62961 -14.86381 55.07366  1.000 63.86895  ? 436 SER   A N   1 
ATOM   3238 C  CA  . SER   A 1 436 ? 42.30231 -14.98011 56.49177  1.000 62.17659  ? 436 SER   A CA  1 
ATOM   3239 C  C   . SER   A 1 436 ? 41.05410 -15.82629 56.71916  1.000 68.64612  ? 436 SER   A C   1 
ATOM   3240 O  O   . SER   A 1 436 ? 41.00812 -16.63600 57.65298  1.000 67.71424  ? 436 SER   A O   1 
ATOM   3241 C  CB  . SER   A 1 436 ? 42.12480 -13.58932 57.10021  1.000 56.93077  ? 436 SER   A CB  1 
ATOM   3242 O  OG  . SER   A 1 436 ? 41.11300 -12.86306 56.42396  1.000 66.26256  ? 436 SER   A OG  1 
ATOM   3243 N  N   . ASP   A 1 437 ? 40.03065 -15.66018 55.87602  1.000 72.23742  ? 437 ASP   A N   1 
ATOM   3244 C  CA  . ASP   A 1 437 ? 38.75083 -16.32464 56.09886  1.000 69.26353  ? 437 ASP   A CA  1 
ATOM   3245 C  C   . ASP   A 1 437 ? 38.25130 -17.08386 54.87376  1.000 63.19979  ? 437 ASP   A C   1 
ATOM   3246 O  O   . ASP   A 1 437 ? 37.07003 -17.43242 54.81774  1.000 62.35110  ? 437 ASP   A O   1 
ATOM   3247 C  CB  . ASP   A 1 437 ? 37.69194 -15.31308 56.54605  1.000 72.24737  ? 437 ASP   A CB  1 
ATOM   3248 C  CG  . ASP   A 1 437 ? 37.39205 -14.27444 55.48237  1.000 76.94369  ? 437 ASP   A CG  1 
ATOM   3249 O  OD1 . ASP   A 1 437 ? 38.28805 -13.98785 54.65868  1.000 77.27469  ? 437 ASP   A OD1 1 
ATOM   3250 O  OD2 . ASP   A 1 437 ? 36.26261 -13.74440 55.47004  1.000 79.20523  ? 437 ASP   A OD2 1 
ATOM   3251 N  N   . CYS   A 1 438 ? 39.11647 -17.35535 53.89451  1.000 62.50197  ? 438 CYS   A N   1 
ATOM   3252 C  CA  . CYS   A 1 438 ? 38.66822 -18.07407 52.70418  1.000 62.61260  ? 438 CYS   A CA  1 
ATOM   3253 C  C   . CYS   A 1 438 ? 38.23506 -19.49526 53.04307  1.000 63.99500  ? 438 CYS   A C   1 
ATOM   3254 O  O   . CYS   A 1 438 ? 37.20353 -19.97212 52.55437  1.000 64.76041  ? 438 CYS   A O   1 
ATOM   3255 C  CB  . CYS   A 1 438 ? 39.77360 -18.09452 51.64797  1.000 67.55336  ? 438 CYS   A CB  1 
ATOM   3256 S  SG  . CYS   A 1 438 ? 39.35929 -19.01132 50.14789  1.000 60.82243  ? 438 CYS   A SG  1 
ATOM   3257 N  N   . PHE   A 1 439 ? 39.00704 -20.18644 53.88209  1.000 67.43156  ? 439 PHE   A N   1 
ATOM   3258 C  CA  . PHE   A 1 439 ? 38.74654 -21.57810 54.22702  1.000 60.57573  ? 439 PHE   A CA  1 
ATOM   3259 C  C   . PHE   A 1 439 ? 38.00598 -21.72181 55.55276  1.000 56.38914  ? 439 PHE   A C   1 
ATOM   3260 O  O   . PHE   A 1 439 ? 38.20261 -22.71016 56.26781  1.000 57.99856  ? 439 PHE   A O   1 
ATOM   3261 C  CB  . PHE   A 1 439 ? 40.05585 -22.36395 54.26901  1.000 58.57619  ? 439 PHE   A CB  1 
ATOM   3262 C  CG  . PHE   A 1 439 ? 40.92694 -22.16349 53.06100  1.000 68.15050  ? 439 PHE   A CG  1 
ATOM   3263 C  CD1 . PHE   A 1 439 ? 40.57906 -22.71482 51.83909  1.000 73.49742  ? 439 PHE   A CD1 1 
ATOM   3264 C  CD2 . PHE   A 1 439 ? 42.10185 -21.43459 53.15156  1.000 69.87714  ? 439 PHE   A CD2 1 
ATOM   3265 C  CE1 . PHE   A 1 439 ? 41.38100 -22.53443 50.72770  1.000 73.15049  ? 439 PHE   A CE1 1 
ATOM   3266 C  CE2 . PHE   A 1 439 ? 42.90853 -21.25174 52.04412  1.000 71.17237  ? 439 PHE   A CE2 1 
ATOM   3267 C  CZ  . PHE   A 1 439 ? 42.54740 -21.80246 50.83092  1.000 72.35657  ? 439 PHE   A CZ  1 
ATOM   3268 N  N   . ALA   A 1 440 ? 37.15093 -20.75784 55.89308  1.000 57.85941  ? 440 ALA   A N   1 
ATOM   3269 C  CA  . ALA   A 1 440 ? 36.43509 -20.78927 57.16259  1.000 59.53061  ? 440 ALA   A CA  1 
ATOM   3270 C  C   . ALA   A 1 440 ? 35.14850 -21.60123 57.10284  1.000 63.06743  ? 440 ALA   A C   1 
ATOM   3271 O  O   . ALA   A 1 440 ? 34.68919 -22.09522 58.13950  1.000 60.35089  ? 440 ALA   A O   1 
ATOM   3272 C  CB  . ALA   A 1 440 ? 36.11484 -19.36400 57.62305  1.000 60.62951  ? 440 ALA   A CB  1 
ATOM   3273 N  N   . ALA   A 1 441 ? 34.55828 -21.75542 55.92080  1.000 63.41943  ? 441 ALA   A N   1 
ATOM   3274 C  CA  . ALA   A 1 441 ? 33.27762 -22.43871 55.79070  1.000 61.37789  ? 441 ALA   A CA  1 
ATOM   3275 C  C   . ALA   A 1 441 ? 33.49405 -23.94410 55.69338  1.000 64.37729  ? 441 ALA   A C   1 
ATOM   3276 O  O   . ALA   A 1 441 ? 34.15357 -24.42357 54.76571  1.000 65.42864  ? 441 ALA   A O   1 
ATOM   3277 C  CB  . ALA   A 1 441 ? 32.52414 -21.92426 54.56689  1.000 62.59111  ? 441 ALA   A CB  1 
ATOM   3278 N  N   . TRP   A 1 442 ? 32.94184 -24.68555 56.65080  1.000 64.16492  ? 442 TRP   A N   1 
ATOM   3279 C  CA  . TRP   A 1 442 ? 32.93475 -26.14772 56.63345  1.000 63.85447  ? 442 TRP   A CA  1 
ATOM   3280 C  C   . TRP   A 1 442 ? 31.48340 -26.59597 56.76597  1.000 70.25634  ? 442 TRP   A C   1 
ATOM   3281 O  O   . TRP   A 1 442 ? 30.92437 -26.59615 57.86758  1.000 75.46990  ? 442 TRP   A O   1 
ATOM   3282 C  CB  . TRP   A 1 442 ? 33.80274 -26.72510 57.74767  1.000 58.84980  ? 442 TRP   A CB  1 
ATOM   3283 C  CG  . TRP   A 1 442 ? 35.25533 -26.79536 57.39864  1.000 62.58280  ? 442 TRP   A CG  1 
ATOM   3284 C  CD1 . TRP   A 1 442 ? 36.22868 -25.90863 57.75441  1.000 72.51126  ? 442 TRP   A CD1 1 
ATOM   3285 C  CD2 . TRP   A 1 442 ? 35.90121 -27.80894 56.61862  1.000 63.43697  ? 442 TRP   A CD2 1 
ATOM   3286 N  NE1 . TRP   A 1 442 ? 37.44152 -26.30823 57.24666  1.000 74.63473  ? 442 TRP   A NE1 1 
ATOM   3287 C  CE2 . TRP   A 1 442 ? 37.26721 -27.47197 56.54498  1.000 69.71841  ? 442 TRP   A CE2 1 
ATOM   3288 C  CE3 . TRP   A 1 442 ? 35.45718 -28.96891 55.97650  1.000 66.13684  ? 442 TRP   A CE3 1 
ATOM   3289 C  CZ2 . TRP   A 1 442 ? 38.19266 -28.25255 55.85528  1.000 75.40541  ? 442 TRP   A CZ2 1 
ATOM   3290 C  CZ3 . TRP   A 1 442 ? 36.37799 -29.74238 55.29245  1.000 67.66215  ? 442 TRP   A CZ3 1 
ATOM   3291 C  CH2 . TRP   A 1 442 ? 37.72916 -29.38110 55.23732  1.000 72.58743  ? 442 TRP   A CH2 1 
ATOM   3292 N  N   . VAL   A 1 443 ? 30.87655 -26.97997 55.64723  1.000 69.73301  ? 443 VAL   A N   1 
ATOM   3293 C  CA  . VAL   A 1 443 ? 29.45867 -27.30680 55.61317  1.000 65.72107  ? 443 VAL   A CA  1 
ATOM   3294 C  C   . VAL   A 1 443 ? 29.28248 -28.80632 55.41357  1.000 67.69927  ? 443 VAL   A C   1 
ATOM   3295 O  O   . VAL   A 1 443 ? 30.17165 -29.51415 54.92932  1.000 67.90740  ? 443 VAL   A O   1 
ATOM   3296 C  CB  . VAL   A 1 443 ? 28.71098 -26.51921 54.51740  1.000 66.61569  ? 443 VAL   A CB  1 
ATOM   3297 C  CG1 . VAL   A 1 443 ? 28.94246 -25.02510 54.68581  1.000 70.32997  ? 443 VAL   A CG1 1 
ATOM   3298 C  CG2 . VAL   A 1 443 ? 29.14477 -26.98473 53.13680  1.000 68.45020  ? 443 VAL   A CG2 1 
ATOM   3299 N  N   . SER   A 1 444 ? 28.10570 -29.29164 55.79959  1.000 70.06447  ? 444 SER   A N   1 
ATOM   3300 C  CA  . SER   A 1 444 ? 27.77499 -30.69656 55.61119  1.000 67.81598  ? 444 SER   A CA  1 
ATOM   3301 C  C   . SER   A 1 444 ? 27.48366 -30.96798 54.14067  1.000 62.18008  ? 444 SER   A C   1 
ATOM   3302 O  O   . SER   A 1 444 ? 26.74607 -30.21706 53.49467  1.000 65.31975  ? 444 SER   A O   1 
ATOM   3303 C  CB  . SER   A 1 444 ? 26.57306 -31.07622 56.47454  1.000 70.65540  ? 444 SER   A CB  1 
ATOM   3304 O  OG  . SER   A 1 444 ? 26.25046 -32.44759 56.33240  1.000 72.82003  ? 444 SER   A OG  1 
ATOM   3305 N  N   . ALA   A 1 445 ? 28.07241 -32.04301 53.60995  1.000 61.54039  ? 445 ALA   A N   1 
ATOM   3306 C  CA  . ALA   A 1 445 ? 27.88209 -32.36965 52.19998  1.000 60.43591  ? 445 ALA   A CA  1 
ATOM   3307 C  C   . ALA   A 1 445 ? 26.41947 -32.66425 51.89290  1.000 68.39803  ? 445 ALA   A C   1 
ATOM   3308 O  O   . ALA   A 1 445 ? 25.92080 -32.31591 50.81592  1.000 63.36118  ? 445 ALA   A O   1 
ATOM   3309 C  CB  . ALA   A 1 445 ? 28.76374 -33.55578 51.81181  1.000 60.39239  ? 445 ALA   A CB  1 
ATOM   3310 N  N   . LYS   A 1 446 ? 25.71530 -33.30686 52.82765  1.000 83.07016  ? 446 LYS   A N   1 
ATOM   3311 C  CA  . LYS   A 1 446 ? 24.28645 -33.53735 52.64429  1.000 83.43734  ? 446 LYS   A CA  1 
ATOM   3312 C  C   . LYS   A 1 446 ? 23.51446 -32.22347 52.65378  1.000 76.79237  ? 446 LYS   A C   1 
ATOM   3313 O  O   . LYS   A 1 446 ? 22.57738 -32.04147 51.86812  1.000 78.22994  ? 446 LYS   A O   1 
ATOM   3314 C  CB  . LYS   A 1 446 ? 23.76358 -34.48024 53.72856  1.000 86.94648  ? 446 LYS   A CB  1 
ATOM   3315 C  CG  . LYS   A 1 446 ? 22.28594 -34.81650 53.60625  1.000 99.95323  ? 446 LYS   A CG  1 
ATOM   3316 C  CD  . LYS   A 1 446 ? 21.83497 -35.74704 54.72140  1.000 114.91227 ? 446 LYS   A CD  1 
ATOM   3317 C  CE  . LYS   A 1 446 ? 20.35255 -36.06580 54.60870  1.000 134.12450 ? 446 LYS   A CE  1 
ATOM   3318 N  NZ  . LYS   A 1 446 ? 19.89432 -36.97044 55.69907  1.000 126.57081 ? 446 LYS   A NZ  1 
ATOM   3319 N  N   . ASP   A 1 447 ? 23.89605 -31.29259 53.53182  1.000 65.45223  ? 447 ASP   A N   1 
ATOM   3320 C  CA  . ASP   A 1 447 ? 23.24903 -29.98673 53.55584  1.000 68.67281  ? 447 ASP   A CA  1 
ATOM   3321 C  C   . ASP   A 1 447 ? 23.67080 -29.11832 52.37907  1.000 73.40626  ? 447 ASP   A C   1 
ATOM   3322 O  O   . ASP   A 1 447 ? 22.92648 -28.21016 51.99437  1.000 71.83167  ? 447 ASP   A O   1 
ATOM   3323 C  CB  . ASP   A 1 447 ? 23.55699 -29.26724 54.87013  1.000 69.34910  ? 447 ASP   A CB  1 
ATOM   3324 C  CG  . ASP   A 1 447 ? 23.08114 -30.04149 56.08481  1.000 70.52068  ? 447 ASP   A CG  1 
ATOM   3325 O  OD1 . ASP   A 1 447 ? 22.14370 -30.85407 55.94185  1.000 81.33838  ? 447 ASP   A OD1 1 
ATOM   3326 O  OD2 . ASP   A 1 447 ? 23.64142 -29.83151 57.18148  1.000 66.89070  ? 447 ASP   A OD2 1 
ATOM   3327 N  N   . ALA   A 1 448 ? 24.84309 -29.37754 51.79942  1.000 71.31210  ? 448 ALA   A N   1 
ATOM   3328 C  CA  . ALA   A 1 448 ? 25.32534 -28.60537 50.66267  1.000 65.33721  ? 448 ALA   A CA  1 
ATOM   3329 C  C   . ALA   A 1 448 ? 24.64506 -28.98302 49.35468  1.000 70.04496  ? 448 ALA   A C   1 
ATOM   3330 O  O   . ALA   A 1 448 ? 24.88594 -28.32141 48.33937  1.000 71.36412  ? 448 ALA   A O   1 
ATOM   3331 C  CB  . ALA   A 1 448 ? 26.83926 -28.77361 50.51618  1.000 61.57771  ? 448 ALA   A CB  1 
ATOM   3332 N  N   . GLY   A 1 449 ? 23.81302 -30.02262 49.34990  1.000 71.47093  ? 449 GLY   A N   1 
ATOM   3333 C  CA  . GLY   A 1 449 ? 23.10806 -30.43583 48.15652  1.000 72.77392  ? 449 GLY   A CA  1 
ATOM   3334 C  C   . GLY   A 1 449 ? 23.80996 -31.48095 47.31876  1.000 74.04592  ? 449 GLY   A C   1 
ATOM   3335 O  O   . GLY   A 1 449 ? 23.24459 -31.92187 46.30968  1.000 81.71829  ? 449 GLY   A O   1 
ATOM   3336 N  N   . PHE   A 1 450 ? 25.01745 -31.89218 47.69815  1.000 70.99058  ? 450 PHE   A N   1 
ATOM   3337 C  CA  . PHE   A 1 450 ? 25.77530 -32.89460 46.95188  1.000 72.02920  ? 450 PHE   A CA  1 
ATOM   3338 C  C   . PHE   A 1 450 ? 25.36550 -34.27186 47.45748  1.000 77.32632  ? 450 PHE   A C   1 
ATOM   3339 O  O   . PHE   A 1 450 ? 25.82462 -34.72442 48.50906  1.000 76.04191  ? 450 PHE   A O   1 
ATOM   3340 C  CB  . PHE   A 1 450 ? 27.27265 -32.65794 47.10692  1.000 68.57436  ? 450 PHE   A CB  1 
ATOM   3341 C  CG  . PHE   A 1 450 ? 27.71652 -31.29399 46.66429  1.000 66.37843  ? 450 PHE   A CG  1 
ATOM   3342 C  CD1 . PHE   A 1 450 ? 27.22892 -30.73896 45.49259  1.000 72.21468  ? 450 PHE   A CD1 1 
ATOM   3343 C  CD2 . PHE   A 1 450 ? 28.60990 -30.56031 47.42674  1.000 74.62508  ? 450 PHE   A CD2 1 
ATOM   3344 C  CE1 . PHE   A 1 450 ? 27.63239 -29.48132 45.08353  1.000 80.22801  ? 450 PHE   A CE1 1 
ATOM   3345 C  CE2 . PHE   A 1 450 ? 29.01656 -29.30168 47.02416  1.000 80.70505  ? 450 PHE   A CE2 1 
ATOM   3346 C  CZ  . PHE   A 1 450 ? 28.52691 -28.76163 45.85080  1.000 81.63286  ? 450 PHE   A CZ  1 
ATOM   3347 N  N   . SER   A 1 451 ? 24.49500 -34.94058 46.70596  1.000 80.84099  ? 451 SER   A N   1 
ATOM   3348 C  CA  . SER   A 1 451 ? 23.97441 -36.24836 47.08856  1.000 86.38388  ? 451 SER   A CA  1 
ATOM   3349 C  C   . SER   A 1 451 ? 24.91284 -37.32746 46.56169  1.000 83.60607  ? 451 SER   A C   1 
ATOM   3350 O  O   . SER   A 1 451 ? 25.05219 -37.50126 45.34651  1.000 94.16912  ? 451 SER   A O   1 
ATOM   3351 C  CB  . SER   A 1 451 ? 22.55855 -36.44156 46.55189  1.000 99.96520  ? 451 SER   A CB  1 
ATOM   3352 O  OG  . SER   A 1 451 ? 22.53232 -36.35190 45.13773  1.000 100.52391 ? 451 SER   A OG  1 
ATOM   3353 N  N   . SER   A 1 452 ? 25.55641 -38.04838 47.47418  1.000 74.50483  ? 452 SER   A N   1 
ATOM   3354 C  CA  . SER   A 1 452 ? 26.40949 -39.15797 47.07568  1.000 79.98389  ? 452 SER   A CA  1 
ATOM   3355 C  C   . SER   A 1 452 ? 25.56650 -40.41741 46.87824  1.000 76.46796  ? 452 SER   A C   1 
ATOM   3356 O  O   . SER   A 1 452 ? 24.59778 -40.63563 47.61122  1.000 76.89220  ? 452 SER   A O   1 
ATOM   3357 C  CB  . SER   A 1 452 ? 27.48866 -39.41000 48.12682  1.000 81.49518  ? 452 SER   A CB  1 
ATOM   3358 O  OG  . SER   A 1 452 ? 28.36968 -40.44346 47.72186  1.000 86.26281  ? 452 SER   A OG  1 
ATOM   3359 N  N   . PRO   A 1 453 ? 25.90264 -41.25179 45.89056  1.000 69.33958  ? 453 PRO   A N   1 
ATOM   3360 C  CA  . PRO   A 1 453 ? 25.09962 -42.46384 45.65630  1.000 69.06287  ? 453 PRO   A CA  1 
ATOM   3361 C  C   . PRO   A 1 453 ? 25.07370 -43.41255 46.84033  1.000 69.57692  ? 453 PRO   A C   1 
ATOM   3362 O  O   . PRO   A 1 453 ? 24.06756 -44.10249 47.04800  1.000 69.71570  ? 453 PRO   A O   1 
ATOM   3363 C  CB  . PRO   A 1 453 ? 25.78022 -43.10319 44.43712  1.000 74.19101  ? 453 PRO   A CB  1 
ATOM   3364 C  CG  . PRO   A 1 453 ? 26.49936 -41.97846 43.76635  1.000 71.91180  ? 453 PRO   A CG  1 
ATOM   3365 C  CD  . PRO   A 1 453 ? 26.95359 -41.07759 44.87412  1.000 71.27842  ? 453 PRO   A CD  1 
ATOM   3366 N  N   . ASP   A 1 454 ? 26.14632 -43.46760 47.62542  1.000 73.33882  ? 454 ASP   A N   1 
ATOM   3367 C  CA  . ASP   A 1 454 ? 26.22825 -44.35583 48.77574  1.000 73.53443  ? 454 ASP   A CA  1 
ATOM   3368 C  C   . ASP   A 1 454 ? 25.69103 -43.72299 50.05284  1.000 77.80170  ? 454 ASP   A C   1 
ATOM   3369 O  O   . ASP   A 1 454 ? 25.84545 -44.30506 51.13074  1.000 78.54258  ? 454 ASP   A O   1 
ATOM   3370 C  CB  . ASP   A 1 454 ? 27.67537 -44.81463 48.98260  1.000 70.29318  ? 454 ASP   A CB  1 
ATOM   3371 C  CG  . ASP   A 1 454 ? 28.66650 -43.66803 48.92975  1.000 74.44965  ? 454 ASP   A CG  1 
ATOM   3372 O  OD1 . ASP   A 1 454 ? 28.22884 -42.49858 48.89755  1.000 82.08071  ? 454 ASP   A OD1 1 
ATOM   3373 O  OD2 . ASP   A 1 454 ? 29.88571 -43.93849 48.91565  1.000 71.62847  ? 454 ASP   A OD2 1 
ATOM   3374 N  N   . GLY   A 1 455 ? 25.06589 -42.55456 49.95792  1.000 83.91277  ? 455 GLY   A N   1 
ATOM   3375 C  CA  . GLY   A 1 455 ? 24.49722 -41.92313 51.13716  1.000 89.84579  ? 455 GLY   A CA  1 
ATOM   3376 C  C   . GLY   A 1 455 ? 25.52591 -41.47614 52.15106  1.000 89.03764  ? 455 GLY   A C   1 
ATOM   3377 O  O   . GLY   A 1 455 ? 25.30659 -41.62058 53.36031  1.000 99.41436  ? 455 GLY   A O   1 
ATOM   3378 N  N   . SER   A 1 456 ? 26.64789 -40.93972 51.68634  1.000 77.92386  ? 456 SER   A N   1 
ATOM   3379 C  CA  . SER   A 1 456 ? 27.69875 -40.44481 52.56050  1.000 77.86763  ? 456 SER   A CA  1 
ATOM   3380 C  C   . SER   A 1 456 ? 27.53489 -38.95048 52.79905  1.000 81.52877  ? 456 SER   A C   1 
ATOM   3381 O  O   . SER   A 1 456 ? 26.85684 -38.24622 52.04820  1.000 80.65365  ? 456 SER   A O   1 
ATOM   3382 C  CB  . SER   A 1 456 ? 29.08286 -40.73136 51.97339  1.000 74.73987  ? 456 SER   A CB  1 
ATOM   3383 O  OG  . SER   A 1 456 ? 30.09339 -40.29908 52.86392  1.000 85.42960  ? 456 SER   A OG  1 
ATOM   3384 N  N   . ASP   A 1 457 ? 28.16543 -38.47422 53.86704  1.000 85.33271  ? 457 ASP   A N   1 
ATOM   3385 C  CA  . ASP   A 1 457 ? 28.09376 -37.05791 54.19450  1.000 81.59227  ? 457 ASP   A CA  1 
ATOM   3386 C  C   . ASP   A 1 457 ? 29.34675 -36.60101 54.93491  1.000 78.97462  ? 457 ASP   A C   1 
ATOM   3387 O  O   . ASP   A 1 457 ? 29.35977 -36.57837 56.17192  1.000 85.18054  ? 457 ASP   A O   1 
ATOM   3388 C  CB  . ASP   A 1 457 ? 26.84793 -36.77200 55.03408  1.000 79.77034  ? 457 ASP   A CB  1 
ATOM   3389 C  CG  . ASP   A 1 457 ? 26.77839 -35.33562 55.50263  1.000 76.24670  ? 457 ASP   A CG  1 
ATOM   3390 O  OD1 . ASP   A 1 457 ? 26.85678 -34.42866 54.65490  1.000 85.08125  ? 457 ASP   A OD1 1 
ATOM   3391 O  OD2 . ASP   A 1 457 ? 26.64908 -35.10743 56.72880  1.000 74.48873  ? 457 ASP   A OD2 1 
ATOM   3392 N  N   . PRO   A 1 458 ? 30.42481 -36.23714 54.22695  1.000 70.16809  ? 458 PRO   A N   1 
ATOM   3393 C  CA  . PRO   A 1 458 ? 31.57836 -35.64129 54.91305  1.000 71.70946  ? 458 PRO   A CA  1 
ATOM   3394 C  C   . PRO   A 1 458 ? 31.41138 -34.14045 55.08837  1.000 71.23166  ? 458 PRO   A C   1 
ATOM   3395 O  O   . PRO   A 1 458 ? 30.34324 -33.58781 54.80308  1.000 72.52944  ? 458 PRO   A O   1 
ATOM   3396 C  CB  . PRO   A 1 458 ? 32.74511 -35.97800 53.97974  1.000 71.55441  ? 458 PRO   A CB  1 
ATOM   3397 C  CG  . PRO   A 1 458 ? 32.11978 -35.97461 52.62730  1.000 69.59910  ? 458 PRO   A CG  1 
ATOM   3398 C  CD  . PRO   A 1 458 ? 30.70786 -36.49089 52.80211  1.000 67.46578  ? 458 PRO   A CD  1 
ATOM   3399 N  N   . LYS   A 1 459 ? 32.45432 -33.47396 55.56926  1.000 68.04768  ? 459 LYS   A N   1 
ATOM   3400 C  CA  . LYS   A 1 459 ? 32.45584 -32.02531 55.70843  1.000 64.89049  ? 459 LYS   A CA  1 
ATOM   3401 C  C   . LYS   A 1 459 ? 33.28656 -31.42496 54.58251  1.000 67.33059  ? 459 LYS   A C   1 
ATOM   3402 O  O   . LYS   A 1 459 ? 34.39265 -31.89807 54.30123  1.000 70.11020  ? 459 LYS   A O   1 
ATOM   3403 C  CB  . LYS   A 1 459 ? 33.00938 -31.60593 57.07111  1.000 66.92024  ? 459 LYS   A CB  1 
ATOM   3404 C  CG  . LYS   A 1 459 ? 32.59983 -32.52310 58.21947  1.000 67.22208  ? 459 LYS   A CG  1 
ATOM   3405 C  CD  . LYS   A 1 459 ? 31.08858 -32.66494 58.33423  1.000 70.19029  ? 459 LYS   A CD  1 
ATOM   3406 C  CE  . LYS   A 1 459 ? 30.72300 -33.91961 59.11253  1.000 70.31561  ? 459 LYS   A CE  1 
ATOM   3407 N  NZ  . LYS   A 1 459 ? 29.25453 -34.16447 59.13723  1.000 68.97289  ? 459 LYS   A NZ  1 
ATOM   3408 N  N   . LEU   A 1 460 ? 32.75298 -30.39142 53.93852  1.000 65.34847  ? 460 LEU   A N   1 
ATOM   3409 C  CA  . LEU   A 1 460 ? 33.37729 -29.79820 52.76651  1.000 62.35652  ? 460 LEU   A CA  1 
ATOM   3410 C  C   . LEU   A 1 460 ? 33.67853 -28.32930 53.02055  1.000 63.31996  ? 460 LEU   A C   1 
ATOM   3411 O  O   . LEU   A 1 460 ? 32.86164 -27.60680 53.60276  1.000 64.62213  ? 460 LEU   A O   1 
ATOM   3412 C  CB  . LEU   A 1 460 ? 32.48091 -29.94451 51.53282  1.000 63.41580  ? 460 LEU   A CB  1 
ATOM   3413 C  CG  . LEU   A 1 460 ? 32.07164 -31.37368 51.17060  1.000 61.12702  ? 460 LEU   A CG  1 
ATOM   3414 C  CD1 . LEU   A 1 460 ? 31.21937 -31.38586 49.91137  1.000 61.37157  ? 460 LEU   A CD1 1 
ATOM   3415 C  CD2 . LEU   A 1 460 ? 33.29838 -32.25700 51.00339  1.000 63.53992  ? 460 LEU   A CD2 1 
ATOM   3416 N  N   . ASN   A 1 461 ? 34.85805 -27.89806 52.58228  1.000 61.39383  ? 461 ASN   A N   1 
ATOM   3417 C  CA  . ASN   A 1 461 ? 35.27200 -26.50691 52.69636  1.000 60.29995  ? 461 ASN   A CA  1 
ATOM   3418 C  C   . ASN   A 1 461 ? 34.84175 -25.76110 51.43943  1.000 62.01513  ? 461 ASN   A C   1 
ATOM   3419 O  O   . ASN   A 1 461 ? 35.29778 -26.08100 50.33610  1.000 64.09765  ? 461 ASN   A O   1 
ATOM   3420 C  CB  . ASN   A 1 461 ? 36.78346 -26.40414 52.89619  1.000 61.21226  ? 461 ASN   A CB  1 
ATOM   3421 C  CG  . ASN   A 1 461 ? 37.22799 -25.00368 53.27494  1.000 59.07289  ? 461 ASN   A CG  1 
ATOM   3422 O  OD1 . ASN   A 1 461 ? 37.25911 -24.10110 52.43851  1.000 58.40758  ? 461 ASN   A OD1 1 
ATOM   3423 N  ND2 . ASN   A 1 461 ? 37.58173 -24.81807 54.54137  1.000 58.92227  ? 461 ASN   A ND2 1 
ATOM   3424 N  N   . LEU   A 1 462 ? 33.96228 -24.77084 51.60800  1.000 60.37382  ? 462 LEU   A N   1 
ATOM   3425 C  CA  . LEU   A 1 462 ? 33.46695 -24.01983 50.45890  1.000 64.94843  ? 462 LEU   A CA  1 
ATOM   3426 C  C   . LEU   A 1 462 ? 34.59195 -23.26076 49.76703  1.000 70.74070  ? 462 LEU   A C   1 
ATOM   3427 O  O   . LEU   A 1 462 ? 34.66816 -23.23823 48.53199  1.000 77.00483  ? 462 LEU   A O   1 
ATOM   3428 C  CB  . LEU   A 1 462 ? 32.36039 -23.06166 50.89831  1.000 64.71769  ? 462 LEU   A CB  1 
ATOM   3429 C  CG  . LEU   A 1 462 ? 31.11905 -23.72072 51.50145  1.000 60.07124  ? 462 LEU   A CG  1 
ATOM   3430 C  CD1 . LEU   A 1 462 ? 30.06568 -22.67883 51.84412  1.000 70.12324  ? 462 LEU   A CD1 1 
ATOM   3431 C  CD2 . LEU   A 1 462 ? 30.55717 -24.76485 50.54968  1.000 55.29045  ? 462 LEU   A CD2 1 
ATOM   3432 N  N   . GLY   A 1 463 ? 35.47721 -22.63631 50.54688  1.000 63.96731  ? 463 GLY   A N   1 
ATOM   3433 C  CA  . GLY   A 1 463 ? 36.59027 -21.91394 49.95330  1.000 60.28860  ? 463 GLY   A CA  1 
ATOM   3434 C  C   . GLY   A 1 463 ? 37.50530 -22.81166 49.14326  1.000 60.28043  ? 463 GLY   A C   1 
ATOM   3435 O  O   . GLY   A 1 463 ? 37.90313 -22.46426 48.02921  1.000 64.01474  ? 463 GLY   A O   1 
ATOM   3436 N  N   . GLY   A 1 464 ? 37.84163 -23.98355 49.68542  1.000 56.56534  ? 464 GLY   A N   1 
ATOM   3437 C  CA  . GLY   A 1 464 ? 38.70186 -24.90262 48.95805  1.000 61.98517  ? 464 GLY   A CA  1 
ATOM   3438 C  C   . GLY   A 1 464 ? 38.04647 -25.45509 47.70659  1.000 67.67495  ? 464 GLY   A C   1 
ATOM   3439 O  O   . GLY   A 1 464 ? 38.68492 -25.55571 46.65398  1.000 75.95379  ? 464 GLY   A O   1 
ATOM   3440 N  N   . LEU   A 1 465 ? 36.76659 -25.82693 47.80363  1.000 63.57812  ? 465 LEU   A N   1 
ATOM   3441 C  CA  . LEU   A 1 465 ? 36.04182 -26.30185 46.62902  1.000 65.85914  ? 465 LEU   A CA  1 
ATOM   3442 C  C   . LEU   A 1 465 ? 36.00199 -25.23701 45.54199  1.000 66.96378  ? 465 LEU   A C   1 
ATOM   3443 O  O   . LEU   A 1 465 ? 36.22556 -25.53261 44.36212  1.000 67.88676  ? 465 LEU   A O   1 
ATOM   3444 C  CB  . LEU   A 1 465 ? 34.62275 -26.71874 47.01711  1.000 61.68421  ? 465 LEU   A CB  1 
ATOM   3445 C  CG  . LEU   A 1 465 ? 34.45728 -27.99288 47.84577  1.000 59.89095  ? 465 LEU   A CG  1 
ATOM   3446 C  CD1 . LEU   A 1 465 ? 33.00729 -28.16295 48.26952  1.000 58.24818  ? 465 LEU   A CD1 1 
ATOM   3447 C  CD2 . LEU   A 1 465 ? 34.93252 -29.20488 47.06268  1.000 66.42153  ? 465 LEU   A CD2 1 
ATOM   3448 N  N   . LEU   A 1 466 ? 35.73279 -23.98691 45.92301  1.000 64.71856  ? 466 LEU   A N   1 
ATOM   3449 C  CA  . LEU   A 1 466 ? 35.66829 -22.91476 44.93673  1.000 70.11816  ? 466 LEU   A CA  1 
ATOM   3450 C  C   . LEU   A 1 466 ? 37.03953 -22.63189 44.33408  1.000 69.98457  ? 466 LEU   A C   1 
ATOM   3451 O  O   . LEU   A 1 466 ? 37.15110 -22.37334 43.12987  1.000 71.87180  ? 466 LEU   A O   1 
ATOM   3452 C  CB  . LEU   A 1 466 ? 35.08468 -21.65732 45.57710  1.000 75.20499  ? 466 LEU   A CB  1 
ATOM   3453 C  CG  . LEU   A 1 466 ? 34.80961 -20.46736 44.66047  1.000 75.42379  ? 466 LEU   A CG  1 
ATOM   3454 C  CD1 . LEU   A 1 466 ? 33.98410 -20.89206 43.45635  1.000 70.14735  ? 466 LEU   A CD1 1 
ATOM   3455 C  CD2 . LEU   A 1 466 ? 34.09562 -19.38528 45.44627  1.000 76.62077  ? 466 LEU   A CD2 1 
ATOM   3456 N  N   . LEU   A 1 467 ? 38.09536 -22.68179 45.15186  1.000 65.62874  ? 467 LEU   A N   1 
ATOM   3457 C  CA  . LEU   A 1 467 ? 39.44328 -22.47547 44.63198  1.000 64.84938  ? 467 LEU   A CA  1 
ATOM   3458 C  C   . LEU   A 1 467 ? 39.82589 -23.56894 43.64409  1.000 66.84270  ? 467 LEU   A C   1 
ATOM   3459 O  O   . LEU   A 1 467 ? 40.44898 -23.29384 42.61192  1.000 71.31445  ? 467 LEU   A O   1 
ATOM   3460 C  CB  . LEU   A 1 467 ? 40.44858 -22.41911 45.78232  1.000 62.06432  ? 467 LEU   A CB  1 
ATOM   3461 C  CG  . LEU   A 1 467 ? 40.99860 -21.04163 46.15717  1.000 59.75076  ? 467 LEU   A CG  1 
ATOM   3462 C  CD1 . LEU   A 1 467 ? 39.87359 -20.09540 46.53386  1.000 58.85207  ? 467 LEU   A CD1 1 
ATOM   3463 C  CD2 . LEU   A 1 467 ? 42.00429 -21.15967 47.29143  1.000 67.71479  ? 467 LEU   A CD2 1 
ATOM   3464 N  N   . GLN   A 1 468 ? 39.46176 -24.81796 43.94208  1.000 65.61574  ? 468 GLN   A N   1 
ATOM   3465 C  CA  . GLN   A 1 468 ? 39.76618 -25.90618 43.02006  1.000 76.13852  ? 468 GLN   A CA  1 
ATOM   3466 C  C   . GLN   A 1 468 ? 38.91075 -25.83165 41.76168  1.000 75.87467  ? 468 GLN   A C   1 
ATOM   3467 O  O   . GLN   A 1 468 ? 39.35409 -26.25378 40.68751  1.000 84.45477  ? 468 GLN   A O   1 
ATOM   3468 C  CB  . GLN   A 1 468 ? 39.58236 -27.25336 43.71789  1.000 76.49346  ? 468 GLN   A CB  1 
ATOM   3469 C  CG  . GLN   A 1 468 ? 40.59176 -27.51226 44.82533  1.000 72.53249  ? 468 GLN   A CG  1 
ATOM   3470 C  CD  . GLN   A 1 468 ? 40.38824 -28.85352 45.49986  1.000 86.52278  ? 468 GLN   A CD  1 
ATOM   3471 O  OE1 . GLN   A 1 468 ? 39.32193 -29.45961 45.39389  1.000 89.95182  ? 468 GLN   A OE1 1 
ATOM   3472 N  NE2 . GLN   A 1 468 ? 41.41516 -29.32697 46.19659  1.000 95.37418  ? 468 GLN   A NE2 1 
ATOM   3473 N  N   . ALA   A 1 469 ? 37.69097 -25.29996 41.86987  1.000 65.99468  ? 469 ALA   A N   1 
ATOM   3474 C  CA  . ALA   A 1 469 ? 36.85682 -25.13094 40.68490  1.000 68.98687  ? 469 ALA   A CA  1 
ATOM   3475 C  C   . ALA   A 1 469 ? 37.39125 -24.02216 39.78716  1.000 75.36014  ? 469 ALA   A C   1 
ATOM   3476 O  O   . ALA   A 1 469 ? 37.33324 -24.13032 38.55655  1.000 79.29136  ? 469 ALA   A O   1 
ATOM   3477 C  CB  . ALA   A 1 469 ? 35.41363 -24.84179 41.09429  1.000 71.94859  ? 469 ALA   A CB  1 
ATOM   3478 N  N   . LEU   A 1 470 ? 37.91326 -22.94708 40.38365  1.000 76.26641  ? 470 LEU   A N   1 
ATOM   3479 C  CA  . LEU   A 1 470 ? 38.47036 -21.85846 39.58617  1.000 75.99244  ? 470 LEU   A CA  1 
ATOM   3480 C  C   . LEU   A 1 470 ? 39.74428 -22.29243 38.87088  1.000 73.23841  ? 470 LEU   A C   1 
ATOM   3481 O  O   . LEU   A 1 470 ? 39.94842 -21.95900 37.69776  1.000 69.09485  ? 470 LEU   A O   1 
ATOM   3482 C  CB  . LEU   A 1 470 ? 38.73709 -20.64059 40.47121  1.000 71.85476  ? 470 LEU   A CB  1 
ATOM   3483 C  CG  . LEU   A 1 470 ? 37.51297 -19.95690 41.08556  1.000 62.95292  ? 470 LEU   A CG  1 
ATOM   3484 C  CD1 . LEU   A 1 470 ? 37.93501 -18.84630 42.03510  1.000 54.57223  ? 470 LEU   A CD1 1 
ATOM   3485 C  CD2 . LEU   A 1 470 ? 36.59263 -19.41789 40.00169  1.000 69.02760  ? 470 LEU   A CD2 1 
ATOM   3486 N  N   . LEU   A 1 471 ? 40.61394 -23.03498 39.55955  1.000 71.15839  ? 471 LEU   A N   1 
ATOM   3487 C  CA  . LEU   A 1 471 ? 41.83464 -23.56701 38.96575  1.000 73.35990  ? 471 LEU   A CA  1 
ATOM   3488 C  C   . LEU   A 1 471 ? 41.64992 -24.97747 38.41954  1.000 76.90311  ? 471 LEU   A C   1 
ATOM   3489 O  O   . LEU   A 1 471 ? 42.60157 -25.77057 38.41785  1.000 77.92524  ? 471 LEU   A O   1 
ATOM   3490 C  CB  . LEU   A 1 471 ? 42.97290 -23.53342 39.98635  1.000 76.09962  ? 471 LEU   A CB  1 
ATOM   3491 C  CG  . LEU   A 1 471 ? 43.29286 -22.16337 40.58804  1.000 68.86878  ? 471 LEU   A CG  1 
ATOM   3492 C  CD1 . LEU   A 1 471 ? 44.50815 -22.24531 41.49975  1.000 78.25771  ? 471 LEU   A CD1 1 
ATOM   3493 C  CD2 . LEU   A 1 471 ? 43.50524 -21.12833 39.49368  1.000 70.39828  ? 471 LEU   A CD2 1 
ATOM   3494 N  N   . GLU   A 1 472 ? 40.44244 -25.30908 37.95619  1.000 76.68685  ? 472 GLU   A N   1 
ATOM   3495 C  CA  . GLU   A 1 472 ? 40.17659 -26.64642 37.43787  1.000 83.89361  ? 472 GLU   A CA  1 
ATOM   3496 C  C   . GLU   A 1 472 ? 40.97317 -26.93264 36.17108  1.000 89.56463  ? 472 GLU   A C   1 
ATOM   3497 O  O   . GLU   A 1 472 ? 41.39981 -28.07253 35.95272  1.000 90.95916  ? 472 GLU   A O   1 
ATOM   3498 C  CB  . GLU   A 1 472 ? 38.67728 -26.80802 37.17985  1.000 85.49764  ? 472 GLU   A CB  1 
ATOM   3499 C  CG  . GLU   A 1 472 ? 38.28849 -28.07261 36.43489  1.000 88.13262  ? 472 GLU   A CG  1 
ATOM   3500 C  CD  . GLU   A 1 472 ? 36.78714 -28.27151 36.37839  1.000 87.94138  ? 472 GLU   A CD  1 
ATOM   3501 O  OE1 . GLU   A 1 472 ? 36.06686 -27.58206 37.13160  1.000 81.28725  ? 472 GLU   A OE1 1 
ATOM   3502 O  OE2 . GLU   A 1 472 ? 36.32685 -29.11519 35.58103  1.000 88.62500  ? 472 GLU   A OE2 1 
ATOM   3503 N  N   . TYR   A 1 473 ? 41.19503 -25.91998 35.33757  1.000 91.72323  ? 473 TYR   A N   1 
ATOM   3504 C  CA  . TYR   A 1 473 ? 41.89050 -26.08798 34.06968  1.000 91.57439  ? 473 TYR   A CA  1 
ATOM   3505 C  C   . TYR   A 1 473 ? 43.39652 -25.88394 34.18508  1.000 92.66891  ? 473 TYR   A C   1 
ATOM   3506 O  O   . TYR   A 1 473 ? 44.06922 -25.74219 33.15872  1.000 93.11340  ? 473 TYR   A O   1 
ATOM   3507 C  CB  . TYR   A 1 473 ? 41.31398 -25.12850 33.02445  1.000 90.18418  ? 473 TYR   A CB  1 
ATOM   3508 C  CG  . TYR   A 1 473 ? 39.86974 -25.40537 32.66938  1.000 87.02227  ? 473 TYR   A CG  1 
ATOM   3509 C  CD1 . TYR   A 1 473 ? 38.83657 -24.96228 33.48426  1.000 90.65090  ? 473 TYR   A CD1 1 
ATOM   3510 C  CD2 . TYR   A 1 473 ? 39.53955 -26.10699 31.51771  1.000 86.21362  ? 473 TYR   A CD2 1 
ATOM   3511 C  CE1 . TYR   A 1 473 ? 37.51612 -25.21238 33.16531  1.000 91.39325  ? 473 TYR   A CE1 1 
ATOM   3512 C  CE2 . TYR   A 1 473 ? 38.22097 -26.36140 31.18948  1.000 92.33406  ? 473 TYR   A CE2 1 
ATOM   3513 C  CZ  . TYR   A 1 473 ? 37.21384 -25.91171 32.01694  1.000 91.52170  ? 473 TYR   A CZ  1 
ATOM   3514 O  OH  . TYR   A 1 473 ? 35.89980 -26.16215 31.69545  1.000 97.60905  ? 473 TYR   A OH  1 
ATOM   3515 N  N   . TRP   A 1 474 ? 43.94045 -25.86503 35.40281  1.000 90.08291  ? 474 TRP   A N   1 
ATOM   3516 C  CA  . TRP   A 1 474 ? 45.37399 -25.70322 35.59425  1.000 91.70426  ? 474 TRP   A CA  1 
ATOM   3517 C  C   . TRP   A 1 474 ? 46.01729 -27.07065 35.74595  1.000 95.49303  ? 474 TRP   A C   1 
ATOM   3518 O  O   . TRP   A 1 474 ? 45.72313 -27.77527 36.72494  1.000 96.98620  ? 474 TRP   A O   1 
ATOM   3519 C  CB  . TRP   A 1 474 ? 45.66309 -24.84519 36.82081  1.000 89.02122  ? 474 TRP   A CB  1 
ATOM   3520 C  CG  . TRP   A 1 474 ? 47.06878 -24.32335 36.86482  1.000 92.02352  ? 474 TRP   A CG  1 
ATOM   3521 C  CD1 . TRP   A 1 474 ? 47.96912 -24.30960 35.83973  1.000 95.70077  ? 474 TRP   A CD1 1 
ATOM   3522 C  CD2 . TRP   A 1 474 ? 47.73630 -23.74199 37.99200  1.000 88.65018  ? 474 TRP   A CD2 1 
ATOM   3523 N  NE1 . TRP   A 1 474 ? 49.15421 -23.75439 36.25689  1.000 96.89763  ? 474 TRP   A NE1 1 
ATOM   3524 C  CE2 . TRP   A 1 474 ? 49.03756 -23.39810 37.57457  1.000 93.29020  ? 474 TRP   A CE2 1 
ATOM   3525 C  CE3 . TRP   A 1 474 ? 47.36006 -23.47821 39.31254  1.000 85.31959  ? 474 TRP   A CE3 1 
ATOM   3526 C  CZ2 . TRP   A 1 474 ? 49.96380 -22.80520 38.42983  1.000 93.08411  ? 474 TRP   A CZ2 1 
ATOM   3527 C  CZ3 . TRP   A 1 474 ? 48.28159 -22.88921 40.16034  1.000 90.26022  ? 474 TRP   A CZ3 1 
ATOM   3528 C  CH2 . TRP   A 1 474 ? 49.56773 -22.55923 39.71541  1.000 93.86791  ? 474 TRP   A CH2 1 
ATOM   3529 N  N   . PRO   A 1 475 ? 46.88172 -27.49172 34.81940  1.000 99.05142  ? 475 PRO   A N   1 
ATOM   3530 C  CA  . PRO   A 1 475 ? 47.48763 -28.82894 34.93468  1.000 93.66071  ? 475 PRO   A CA  1 
ATOM   3531 C  C   . PRO   A 1 475 ? 48.38639 -28.99457 36.14749  1.000 92.47376  ? 475 PRO   A C   1 
ATOM   3532 O  O   . PRO   A 1 475 ? 48.60494 -30.13236 36.58225  1.000 95.88808  ? 475 PRO   A O   1 
ATOM   3533 C  CB  . PRO   A 1 475 ? 48.28276 -28.96892 33.62828  1.000 99.53540  ? 475 PRO   A CB  1 
ATOM   3534 C  CG  . PRO   A 1 475 ? 47.66319 -27.97990 32.69114  1.000 105.11173 ? 475 PRO   A CG  1 
ATOM   3535 C  CD  . PRO   A 1 475 ? 47.23543 -26.83178 33.55231  1.000 104.04573 ? 475 PRO   A CD  1 
ATOM   3536 N  N   . ARG   A 1 476 ? 48.91979 -27.90463 36.70583  1.000 91.63698  ? 476 ARG   A N   1 
ATOM   3537 C  CA  . ARG   A 1 476 ? 49.76278 -28.02803 37.89029  1.000 95.53245  ? 476 ARG   A CA  1 
ATOM   3538 C  C   . ARG   A 1 476 ? 48.96732 -28.52516 39.09078  1.000 97.24553  ? 476 ARG   A C   1 
ATOM   3539 O  O   . ARG   A 1 476 ? 49.51972 -29.21123 39.95847  1.000 94.80079  ? 476 ARG   A O   1 
ATOM   3540 C  CB  . ARG   A 1 476 ? 50.43223 -26.68925 38.20226  1.000 95.11511  ? 476 ARG   A CB  1 
ATOM   3541 C  CG  . ARG   A 1 476 ? 51.50329 -26.76638 39.27944  1.000 93.90577  ? 476 ARG   A CG  1 
ATOM   3542 C  CD  . ARG   A 1 476 ? 52.30212 -25.47638 39.35953  1.000 96.19530  ? 476 ARG   A CD  1 
ATOM   3543 N  NE  . ARG   A 1 476 ? 53.34498 -25.54175 40.37640  1.000 100.53047 ? 476 ARG   A NE  1 
ATOM   3544 C  CZ  . ARG   A 1 476 ? 53.20661 -25.10462 41.62059  1.000 101.05858 ? 476 ARG   A CZ  1 
ATOM   3545 N  NH1 . ARG   A 1 476 ? 52.07777 -24.55607 42.03899  1.000 98.21952  ? 476 ARG   A NH1 1 
ATOM   3546 N  NH2 . ARG   A 1 476 ? 54.22729 -25.21847 42.46567  1.000 105.72163 ? 476 ARG   A NH2 1 
ATOM   3547 N  N   . THR   A 1 477 ? 47.67618 -28.19500 39.15751  1.000 100.27816 ? 477 THR   A N   1 
ATOM   3548 C  CA  . THR   A 1 477 ? 46.80728 -28.75640 40.18284  1.000 95.08243  ? 477 THR   A CA  1 
ATOM   3549 C  C   . THR   A 1 477 ? 46.39779 -30.18879 39.87103  1.000 94.32476  ? 477 THR   A C   1 
ATOM   3550 O  O   . THR   A 1 477 ? 46.05794 -30.93804 40.79322  1.000 96.29529  ? 477 THR   A O   1 
ATOM   3551 C  CB  . THR   A 1 477 ? 45.55247 -27.89590 40.34913  1.000 95.92625  ? 477 THR   A CB  1 
ATOM   3552 O  OG1 . THR   A 1 477 ? 44.80808 -27.89253 39.12479  1.000 101.24758 ? 477 THR   A OG1 1 
ATOM   3553 C  CG2 . THR   A 1 477 ? 45.92792 -26.46665 40.71232  1.000 93.61178  ? 477 THR   A CG2 1 
ATOM   3554 N  N   . HIS   A 1 478 ? 46.42244 -30.58173 38.59973  1.000 95.36550  ? 478 HIS   A N   1 
ATOM   3555 C  CA  . HIS   A 1 478 ? 46.06410 -31.93836 38.19237  1.000 103.71714 ? 478 HIS   A CA  1 
ATOM   3556 C  C   . HIS   A 1 478 ? 47.13686 -32.90131 38.68299  1.000 105.34935 ? 478 HIS   A C   1 
ATOM   3557 O  O   . HIS   A 1 478 ? 48.23439 -32.96824 38.12524  1.000 101.62117 ? 478 HIS   A O   1 
ATOM   3558 C  CB  . HIS   A 1 478 ? 45.90697 -32.01580 36.67814  1.000 105.49415 ? 478 HIS   A CB  1 
ATOM   3559 C  CG  . HIS   A 1 478 ? 44.71426 -31.27928 36.15280  1.000 100.65494 ? 478 HIS   A CG  1 
ATOM   3560 N  ND1 . HIS   A 1 478 ? 44.23861 -31.45512 34.87129  1.000 99.49485  ? 478 HIS   A ND1 1 
ATOM   3561 C  CD2 . HIS   A 1 478 ? 43.90093 -30.36569 36.73368  1.000 97.94815  ? 478 HIS   A CD2 1 
ATOM   3562 C  CE1 . HIS   A 1 478 ? 43.18360 -30.68232 34.68530  1.000 100.89538 ? 478 HIS   A CE1 1 
ATOM   3563 N  NE2 . HIS   A 1 478 ? 42.95781 -30.01062 35.79995  1.000 100.33142 ? 478 HIS   A NE2 1 
ATOM   3564 N  N   . VAL   A 1 479 ? 46.82164 -33.65316 39.73404  1.000 108.85637 ? 479 VAL   A N   1 
ATOM   3565 C  CA  . VAL   A 1 479 ? 47.74071 -34.61288 40.33420  1.000 115.96790 ? 479 VAL   A CA  1 
ATOM   3566 C  C   . VAL   A 1 479 ? 47.18404 -36.01217 40.11548  1.000 116.39317 ? 479 VAL   A C   1 
ATOM   3567 O  O   . VAL   A 1 479 ? 46.00612 -36.26961 40.39305  1.000 109.21489 ? 479 VAL   A O   1 
ATOM   3568 C  CB  . VAL   A 1 479 ? 47.95095 -34.33069 41.83221  1.000 116.44337 ? 479 VAL   A CB  1 
ATOM   3569 C  CG1 . VAL   A 1 479 ? 48.89617 -35.35601 42.44135  1.000 115.05513 ? 479 VAL   A CG1 1 
ATOM   3570 C  CG2 . VAL   A 1 479 ? 48.48215 -32.91959 42.03622  1.000 107.24446 ? 479 VAL   A CG2 1 
ATOM   3571 N  N   . ASN   A 1 480 ? 48.02746 -36.91110 39.61783  1.000 120.76340 ? 480 ASN   A N   1 
ATOM   3572 C  CA  . ASN   A 1 480 ? 47.62637 -38.29415 39.38933  1.000 120.63358 ? 480 ASN   A CA  1 
ATOM   3573 C  C   . ASN   A 1 480 ? 47.64103 -39.08562 40.69308  1.000 128.66768 ? 480 ASN   A C   1 
ATOM   3574 O  O   . ASN   A 1 480 ? 48.70474 -39.40049 41.22728  1.000 132.37436 ? 480 ASN   A O   1 
ATOM   3575 C  CB  . ASN   A 1 480 ? 48.54344 -38.95751 38.35980  1.000 117.06852 ? 480 ASN   A CB  1 
ATOM   3576 C  CG  . ASN   A 1 480 ? 48.16288 -40.39932 38.08331  1.000 123.57525 ? 480 ASN   A CG  1 
ATOM   3577 O  OD1 . ASN   A 1 480 ? 46.99918 -40.78207 38.20738  1.000 121.17593 ? 480 ASN   A OD1 1 
ATOM   3578 N  ND2 . ASN   A 1 480 ? 49.14674 -41.20907 37.70932  1.000 132.41995 ? 480 ASN   A ND2 1 
ATOM   3579 N  N   . VAL   A 1 500 ? 44.55801 -39.16944 36.95624  1.000 107.30594 ? 500 VAL   A N   1 
ATOM   3580 C  CA  . VAL   A 1 500 ? 44.55855 -37.72091 37.11032  1.000 113.78778 ? 500 VAL   A CA  1 
ATOM   3581 C  C   . VAL   A 1 500 ? 43.12035 -37.20777 37.17482  1.000 114.71814 ? 500 VAL   A C   1 
ATOM   3582 O  O   . VAL   A 1 500 ? 42.23917 -37.71181 36.47708  1.000 111.04380 ? 500 VAL   A O   1 
ATOM   3583 C  CB  . VAL   A 1 500 ? 45.35388 -37.04151 35.96964  1.000 111.78235 ? 500 VAL   A CB  1 
ATOM   3584 C  CG1 . VAL   A 1 500 ? 44.71196 -37.31893 34.61509  1.000 105.09699 ? 500 VAL   A CG1 1 
ATOM   3585 C  CG2 . VAL   A 1 500 ? 45.48320 -35.54764 36.21615  1.000 103.83993 ? 500 VAL   A CG2 1 
ATOM   3586 N  N   . GLN   A 1 501 ? 42.88169 -36.21839 38.02978  1.000 119.78372 ? 501 GLN   A N   1 
ATOM   3587 C  CA  . GLN   A 1 501 ? 41.56421 -35.62432 38.19859  1.000 115.89661 ? 501 GLN   A CA  1 
ATOM   3588 C  C   . GLN   A 1 501 ? 41.54305 -34.20998 37.63265  1.000 105.71301 ? 501 GLN   A C   1 
ATOM   3589 O  O   . GLN   A 1 501 ? 42.56471 -33.66235 37.20948  1.000 100.85940 ? 501 GLN   A O   1 
ATOM   3590 C  CB  . GLN   A 1 501 ? 41.15094 -35.61574 39.67492  1.000 121.16353 ? 501 GLN   A CB  1 
ATOM   3591 C  CG  . GLN   A 1 501 ? 40.82068 -36.98926 40.23351  1.000 122.41130 ? 501 GLN   A CG  1 
ATOM   3592 C  CD  . GLN   A 1 501 ? 40.14405 -36.91792 41.58796  1.000 130.06508 ? 501 GLN   A CD  1 
ATOM   3593 O  OE1 . GLN   A 1 501 ? 39.96268 -35.83668 42.14816  1.000 126.21969 ? 501 GLN   A OE1 1 
ATOM   3594 N  NE2 . GLN   A 1 501 ? 39.76235 -38.07309 42.12025  1.000 134.41136 ? 501 GLN   A NE2 1 
ATOM   3595 N  N   . LYS   A 1 502 ? 40.34815 -33.61745 37.63609  1.000 106.09847 ? 502 LYS   A N   1 
ATOM   3596 C  CA  . LYS   A 1 502 ? 40.14175 -32.29727 37.04249  1.000 105.99756 ? 502 LYS   A CA  1 
ATOM   3597 C  C   . LYS   A 1 502 ? 38.93347 -31.66354 37.72756  1.000 106.42568 ? 502 LYS   A C   1 
ATOM   3598 O  O   . LYS   A 1 502 ? 37.78895 -31.97951 37.38876  1.000 105.31827 ? 502 LYS   A O   1 
ATOM   3599 C  CB  . LYS   A 1 502 ? 39.94301 -32.40669 35.53615  1.000 104.20583 ? 502 LYS   A CB  1 
ATOM   3600 C  CG  . LYS   A 1 502 ? 39.65805 -31.09053 34.83137  1.000 99.12055  ? 502 LYS   A CG  1 
ATOM   3601 C  CD  . LYS   A 1 502 ? 39.55188 -31.29556 33.32680  1.000 91.75133  ? 502 LYS   A CD  1 
ATOM   3602 C  CE  . LYS   A 1 502 ? 39.20360 -30.00259 32.60733  1.000 86.30512  ? 502 LYS   A CE  1 
ATOM   3603 N  NZ  . LYS   A 1 502 ? 37.85657 -29.49700 32.98955  1.000 81.99306  ? 502 LYS   A NZ  1 
ATOM   3604 N  N   . GLY   A 1 503 ? 39.19422 -30.78236 38.68327  1.000 105.42690 ? 503 GLY   A N   1 
ATOM   3605 C  CA  . GLY   A 1 503 ? 38.15220 -30.06093 39.38494  1.000 98.85580  ? 503 GLY   A CA  1 
ATOM   3606 C  C   . GLY   A 1 503 ? 38.09997 -30.42151 40.85863  1.000 91.17669  ? 503 GLY   A C   1 
ATOM   3607 O  O   . GLY   A 1 503 ? 38.98641 -31.08186 41.40757  1.000 91.64619  ? 503 GLY   A O   1 
ATOM   3608 N  N   . ASN   A 1 504 ? 37.02616 -29.96420 41.50339  1.000 85.86347  ? 504 ASN   A N   1 
ATOM   3609 C  CA  . ASN   A 1 504 ? 36.80417 -30.24079 42.91587  1.000 78.51646  ? 504 ASN   A CA  1 
ATOM   3610 C  C   . ASN   A 1 504 ? 36.08825 -31.56131 43.15829  1.000 74.60268  ? 504 ASN   A C   1 
ATOM   3611 O  O   . ASN   A 1 504 ? 36.15922 -32.09339 44.27200  1.000 73.77700  ? 504 ASN   A O   1 
ATOM   3612 C  CB  . ASN   A 1 504 ? 36.00561 -29.10016 43.55993  1.000 74.50521  ? 504 ASN   A CB  1 
ATOM   3613 C  CG  . ASN   A 1 504 ? 34.69759 -28.81251 42.83756  1.000 72.20217  ? 504 ASN   A CG  1 
ATOM   3614 O  OD1 . ASN   A 1 504 ? 33.99800 -29.72369 42.39439  1.000 73.04882  ? 504 ASN   A OD1 1 
ATOM   3615 N  ND2 . ASN   A 1 504 ? 34.36432 -27.53422 42.71568  1.000 70.58172  ? 504 ASN   A ND2 1 
ATOM   3616 N  N   . GLY   A 1 505 ? 35.40255 -32.09504 42.15154  1.000 73.76495  ? 505 GLY   A N   1 
ATOM   3617 C  CA  . GLY   A 1 505 ? 34.68103 -33.34095 42.30018  1.000 69.84198  ? 505 GLY   A CA  1 
ATOM   3618 C  C   . GLY   A 1 505 ? 33.23562 -33.20371 42.71489  1.000 67.56043  ? 505 GLY   A C   1 
ATOM   3619 O  O   . GLY   A 1 505 ? 32.65076 -34.18194 43.19382  1.000 69.97312  ? 505 GLY   A O   1 
ATOM   3620 N  N   . TYR   A 1 506 ? 32.63641 -32.02451 42.54948  1.000 68.44208  ? 506 TYR   A N   1 
ATOM   3621 C  CA  . TYR   A 1 506 ? 31.24822 -31.81807 42.94427  1.000 70.99489  ? 506 TYR   A CA  1 
ATOM   3622 C  C   . TYR   A 1 506 ? 30.52535 -30.89081 41.97516  1.000 68.74266  ? 506 TYR   A C   1 
ATOM   3623 O  O   . TYR   A 1 506 ? 29.36735 -31.13599 41.62160  1.000 68.48211  ? 506 TYR   A O   1 
ATOM   3624 C  CB  . TYR   A 1 506 ? 31.17433 -31.25850 44.36670  1.000 73.52803  ? 506 TYR   A CB  1 
ATOM   3625 C  CG  . TYR   A 1 506 ? 31.58436 -32.24761 45.43383  1.000 68.98659  ? 506 TYR   A CG  1 
ATOM   3626 C  CD1 . TYR   A 1 506 ? 30.68050 -33.17993 45.92548  1.000 65.65052  ? 506 TYR   A CD1 1 
ATOM   3627 C  CD2 . TYR   A 1 506 ? 32.87367 -32.24919 45.95013  1.000 66.11226  ? 506 TYR   A CD2 1 
ATOM   3628 C  CE1 . TYR   A 1 506 ? 31.04845 -34.08703 46.90018  1.000 64.98200  ? 506 TYR   A CE1 1 
ATOM   3629 C  CE2 . TYR   A 1 506 ? 33.25110 -33.15282 46.92561  1.000 61.50185  ? 506 TYR   A CE2 1 
ATOM   3630 C  CZ  . TYR   A 1 506 ? 32.33423 -34.06901 47.39673  1.000 61.48733  ? 506 TYR   A CZ  1 
ATOM   3631 O  OH  . TYR   A 1 506 ? 32.70349 -34.97104 48.36797  1.000 67.49996  ? 506 TYR   A OH  1 
ATOM   3632 N  N   . PHE   A 1 507 ? 31.19370 -29.82417 41.54305  1.000 68.49618  ? 507 PHE   A N   1 
ATOM   3633 C  CA  . PHE   A 1 507 ? 30.59104 -28.86970 40.62500  1.000 67.82408  ? 507 PHE   A CA  1 
ATOM   3634 C  C   . PHE   A 1 507 ? 31.68398 -28.24451 39.77078  1.000 65.93819  ? 507 PHE   A C   1 
ATOM   3635 O  O   . PHE   A 1 507 ? 32.87838 -28.39640 40.03930  1.000 66.47553  ? 507 PHE   A O   1 
ATOM   3636 C  CB  . PHE   A 1 507 ? 29.80048 -27.79076 41.37554  1.000 69.27066  ? 507 PHE   A CB  1 
ATOM   3637 C  CG  . PHE   A 1 507 ? 30.65446 -26.89163 42.22478  1.000 64.51088  ? 507 PHE   A CG  1 
ATOM   3638 C  CD1 . PHE   A 1 507 ? 31.00371 -27.25968 43.51346  1.000 59.45401  ? 507 PHE   A CD1 1 
ATOM   3639 C  CD2 . PHE   A 1 507 ? 31.10299 -25.67492 41.73598  1.000 64.71362  ? 507 PHE   A CD2 1 
ATOM   3640 C  CE1 . PHE   A 1 507 ? 31.78770 -26.43364 44.29674  1.000 65.63915  ? 507 PHE   A CE1 1 
ATOM   3641 C  CE2 . PHE   A 1 507 ? 31.88822 -24.84650 42.51319  1.000 62.59102  ? 507 PHE   A CE2 1 
ATOM   3642 C  CZ  . PHE   A 1 507 ? 32.23046 -25.22541 43.79510  1.000 64.72687  ? 507 PHE   A CZ  1 
ATOM   3643 N  N   . GLN   A 1 508 ? 31.25653 -27.53122 38.73159  1.000 63.87795  ? 508 GLN   A N   1 
ATOM   3644 C  CA  . GLN   A 1 508 ? 32.16128 -26.83458 37.82814  1.000 69.92045  ? 508 GLN   A CA  1 
ATOM   3645 C  C   . GLN   A 1 508 ? 31.66128 -25.41494 37.61730  1.000 70.76034  ? 508 GLN   A C   1 
ATOM   3646 O  O   . GLN   A 1 508 ? 30.49817 -25.21078 37.25513  1.000 73.96894  ? 508 GLN   A O   1 
ATOM   3647 C  CB  . GLN   A 1 508 ? 32.27269 -27.55444 36.47912  1.000 76.11650  ? 508 GLN   A CB  1 
ATOM   3648 C  CG  . GLN   A 1 508 ? 32.91220 -28.92996 36.54652  1.000 76.72910  ? 508 GLN   A CG  1 
ATOM   3649 C  CD  . GLN   A 1 508 ? 33.06649 -29.56328 35.17707  1.000 71.33281  ? 508 GLN   A CD  1 
ATOM   3650 O  OE1 . GLN   A 1 508 ? 32.59974 -29.02220 34.17449  1.000 69.53671  ? 508 GLN   A OE1 1 
ATOM   3651 N  NE2 . GLN   A 1 508 ? 33.72654 -30.71447 35.12764  1.000 74.57677  ? 508 GLN   A NE2 1 
ATOM   3652 N  N   . VAL   A 1 509 ? 32.53574 -24.44095 37.84603  1.000 70.97057  ? 509 VAL   A N   1 
ATOM   3653 C  CA  . VAL   A 1 509 ? 32.22770 -23.04600 37.54546  1.000 69.82086  ? 509 VAL   A CA  1 
ATOM   3654 C  C   . VAL   A 1 509 ? 32.23034 -22.89034 36.02925  1.000 74.80649  ? 509 VAL   A C   1 
ATOM   3655 O  O   . VAL   A 1 509 ? 32.88366 -23.68167 35.33285  1.000 76.64563  ? 509 VAL   A O   1 
ATOM   3656 C  CB  . VAL   A 1 509 ? 33.22869 -22.09143 38.21621  1.000 71.00749  ? 509 VAL   A CB  1 
ATOM   3657 C  CG1 . VAL   A 1 509 ? 33.14939 -22.21892 39.72930  1.000 72.13109  ? 509 VAL   A CG1 1 
ATOM   3658 C  CG2 . VAL   A 1 509 ? 34.64126 -22.36976 37.72535  1.000 74.86722  ? 509 VAL   A CG2 1 
ATOM   3659 N  N   . PRO   A 1 510 ? 31.50894 -21.91996 35.47422  1.000 72.85530  ? 510 PRO   A N   1 
ATOM   3660 C  CA  . PRO   A 1 510 ? 31.52436 -21.71922 34.02083  1.000 72.25779  ? 510 PRO   A CA  1 
ATOM   3661 C  C   . PRO   A 1 510 ? 32.93293 -21.45114 33.52445  1.000 73.05863  ? 510 PRO   A C   1 
ATOM   3662 O  O   . PRO   A 1 510 ? 33.71969 -20.76975 34.19904  1.000 74.99994  ? 510 PRO   A O   1 
ATOM   3663 C  CB  . PRO   A 1 510 ? 30.61928 -20.49419 33.82425  1.000 70.41504  ? 510 PRO   A CB  1 
ATOM   3664 C  CG  . PRO   A 1 510 ? 29.71115 -20.51214 35.00460  1.000 72.58777  ? 510 PRO   A CG  1 
ATOM   3665 C  CD  . PRO   A 1 510 ? 30.54107 -21.03327 36.14358  1.000 71.29274  ? 510 PRO   A CD  1 
ATOM   3666 N  N   . PRO   A 1 511 ? 33.29436 -21.97884 32.35122  1.000 74.45736  ? 511 PRO   A N   1 
ATOM   3667 C  CA  . PRO   A 1 511 ? 34.66309 -21.77803 31.84957  1.000 78.72824  ? 511 PRO   A CA  1 
ATOM   3668 C  C   . PRO   A 1 511 ? 34.97886 -20.33485 31.50104  1.000 82.60361  ? 511 PRO   A C   1 
ATOM   3669 O  O   . PRO   A 1 511 ? 36.16144 -19.97424 31.45184  1.000 81.88779  ? 511 PRO   A O   1 
ATOM   3670 C  CB  . PRO   A 1 511 ? 34.71677 -22.67665 30.60696  1.000 76.30867  ? 511 PRO   A CB  1 
ATOM   3671 C  CG  . PRO   A 1 511 ? 33.29350 -22.78333 30.16421  1.000 76.69255  ? 511 PRO   A CG  1 
ATOM   3672 C  CD  . PRO   A 1 511 ? 32.47287 -22.77536 31.42384  1.000 74.60658  ? 511 PRO   A CD  1 
ATOM   3673 N  N   . HIS   A 1 512 ? 33.96845 -19.49918 31.26073  1.000 79.01398  ? 512 HIS   A N   1 
ATOM   3674 C  CA  . HIS   A 1 512 ? 34.20043 -18.09893 30.93440  1.000 73.78915  ? 512 HIS   A CA  1 
ATOM   3675 C  C   . HIS   A 1 512 ? 34.38966 -17.22438 32.16559  1.000 72.53144  ? 512 HIS   A C   1 
ATOM   3676 O  O   . HIS   A 1 512 ? 34.71315 -16.04173 32.01463  1.000 73.22605  ? 512 HIS   A O   1 
ATOM   3677 C  CB  . HIS   A 1 512 ? 33.03799 -17.55075 30.10203  1.000 77.84958  ? 512 HIS   A CB  1 
ATOM   3678 C  CG  . HIS   A 1 512 ? 31.77490 -17.35491 30.88271  1.000 75.46455  ? 512 HIS   A CG  1 
ATOM   3679 N  ND1 . HIS   A 1 512 ? 30.76932 -18.29666 30.92088  1.000 76.98125  ? 512 HIS   A ND1 1 
ATOM   3680 C  CD2 . HIS   A 1 512 ? 31.35419 -16.32461 31.65474  1.000 73.49726  ? 512 HIS   A CD2 1 
ATOM   3681 C  CE1 . HIS   A 1 512 ? 29.78397 -17.85520 31.68229  1.000 80.09675  ? 512 HIS   A CE1 1 
ATOM   3682 N  NE2 . HIS   A 1 512 ? 30.11406 -16.66109 32.14020  1.000 75.05361  ? 512 HIS   A NE2 1 
ATOM   3683 N  N   . THR   A 1 513 ? 34.19121 -17.77019 33.36720  1.000 78.10666  ? 513 THR   A N   1 
ATOM   3684 C  CA  . THR   A 1 513 ? 34.26051 -17.01286 34.61191  1.000 77.54557  ? 513 THR   A CA  1 
ATOM   3685 C  C   . THR   A 1 513 ? 35.63116 -16.36705 34.77675  1.000 75.54318  ? 513 THR   A C   1 
ATOM   3686 O  O   . THR   A 1 513 ? 36.63471 -17.07093 34.94861  1.000 78.15543  ? 513 THR   A O   1 
ATOM   3687 C  CB  . THR   A 1 513 ? 33.95611 -17.91666 35.80877  1.000 74.68493  ? 513 THR   A CB  1 
ATOM   3688 O  OG1 . THR   A 1 513 ? 32.65819 -18.50373 35.64970  1.000 75.58644  ? 513 THR   A OG1 1 
ATOM   3689 C  CG2 . THR   A 1 513 ? 33.99009 -17.11749 37.10263  1.000 73.85008  ? 513 THR   A CG2 1 
ATOM   3690 N  N   . PRO   A 1 514 ? 35.71523 -15.03665 34.72948  1.000 74.88535  ? 514 PRO   A N   1 
ATOM   3691 C  CA  . PRO   A 1 514 ? 37.02030 -14.36584 34.84039  1.000 76.56554  ? 514 PRO   A CA  1 
ATOM   3692 C  C   . PRO   A 1 514 ? 37.55953 -14.46026 36.26022  1.000 77.66814  ? 514 PRO   A C   1 
ATOM   3693 O  O   . PRO   A 1 514 ? 36.96010 -13.93195 37.20074  1.000 75.98775  ? 514 PRO   A O   1 
ATOM   3694 C  CB  . PRO   A 1 514 ? 36.71083 -12.91400 34.44804  1.000 73.41641  ? 514 PRO   A CB  1 
ATOM   3695 C  CG  . PRO   A 1 514 ? 35.34407 -12.94952 33.81408  1.000 69.83592  ? 514 PRO   A CG  1 
ATOM   3696 C  CD  . PRO   A 1 514 ? 34.62806 -14.07796 34.48036  1.000 73.63568  ? 514 PRO   A CD  1 
ATOM   3697 N  N   . VAL   A 1 515 ? 38.69450 -15.14816 36.40878  1.000 74.42526  ? 515 VAL   A N   1 
ATOM   3698 C  CA  . VAL   A 1 515 ? 39.40899 -15.27104 37.67258  1.000 69.45732  ? 515 VAL   A CA  1 
ATOM   3699 C  C   . VAL   A 1 515 ? 40.52183 -14.23325 37.70510  1.000 71.54119  ? 515 VAL   A C   1 
ATOM   3700 O  O   . VAL   A 1 515 ? 41.24495 -14.03527 36.71509  1.000 76.23003  ? 515 VAL   A O   1 
ATOM   3701 C  CB  . VAL   A 1 515 ? 39.97454 -16.69280 37.85482  1.000 65.43336  ? 515 VAL   A CB  1 
ATOM   3702 C  CG1 . VAL   A 1 515 ? 40.59934 -16.84841 39.23405  1.000 65.26583  ? 515 VAL   A CG1 1 
ATOM   3703 C  CG2 . VAL   A 1 515 ? 38.88581 -17.72990 37.63213  1.000 72.39117  ? 515 VAL   A CG2 1 
ATOM   3704 N  N   . ILE   A 1 516 ? 40.66334 -13.57079 38.85073  1.000 68.44455  ? 516 ILE   A N   1 
ATOM   3705 C  CA  . ILE   A 1 516 ? 41.61417 -12.48699 39.04693  1.000 71.08140  ? 516 ILE   A CA  1 
ATOM   3706 C  C   . ILE   A 1 516 ? 42.40949 -12.76935 40.31336  1.000 77.42145  ? 516 ILE   A C   1 
ATOM   3707 O  O   . ILE   A 1 516 ? 41.86568 -13.27471 41.30101  1.000 82.53115  ? 516 ILE   A O   1 
ATOM   3708 C  CB  . ILE   A 1 516 ? 40.90133 -11.12062 39.15679  1.000 65.05640  ? 516 ILE   A CB  1 
ATOM   3709 C  CG1 . ILE   A 1 516 ? 39.76458 -11.01477 38.13766  1.000 63.66537  ? 516 ILE   A CG1 1 
ATOM   3710 C  CG2 . ILE   A 1 516 ? 41.88891 -9.97953  38.96848  1.000 71.03940  ? 516 ILE   A CG2 1 
ATOM   3711 C  CD1 . ILE   A 1 516 ? 38.88732 -9.79685  38.32858  1.000 66.66156  ? 516 ILE   A CD1 1 
ATOM   3712 N  N   . PHE   A 1 517 ? 43.69737 -12.45225 40.27896  1.000 75.46546  ? 517 PHE   A N   1 
ATOM   3713 C  CA  . PHE   A 1 517 ? 44.55049 -12.42789 41.45900  1.000 73.45266  ? 517 PHE   A CA  1 
ATOM   3714 C  C   . PHE   A 1 517 ? 44.96646 -10.98226 41.67679  1.000 77.35592  ? 517 PHE   A C   1 
ATOM   3715 O  O   . PHE   A 1 517 ? 45.63097 -10.39516 40.81413  1.000 86.19747  ? 517 PHE   A O   1 
ATOM   3716 C  CB  . PHE   A 1 517 ? 45.77722 -13.32276 41.28040  1.000 73.96614  ? 517 PHE   A CB  1 
ATOM   3717 C  CG  . PHE   A 1 517 ? 45.44971 -14.77748 41.11007  1.000 75.22749  ? 517 PHE   A CG  1 
ATOM   3718 C  CD1 . PHE   A 1 517 ? 45.02524 -15.26772 39.88628  1.000 78.37055  ? 517 PHE   A CD1 1 
ATOM   3719 C  CD2 . PHE   A 1 517 ? 45.57734 -15.65761 42.17111  1.000 75.11530  ? 517 PHE   A CD2 1 
ATOM   3720 C  CE1 . PHE   A 1 517 ? 44.72411 -16.60476 39.72689  1.000 79.29797  ? 517 PHE   A CE1 1 
ATOM   3721 C  CE2 . PHE   A 1 517 ? 45.28042 -16.99784 42.01703  1.000 75.29695  ? 517 PHE   A CE2 1 
ATOM   3722 C  CZ  . PHE   A 1 517 ? 44.85366 -17.47195 40.79252  1.000 77.38500  ? 517 PHE   A CZ  1 
ATOM   3723 N  N   . GLY   A 1 518 ? 44.56517 -10.40730 42.80346  1.000 78.74029  ? 518 GLY   A N   1 
ATOM   3724 C  CA  . GLY   A 1 518 ? 44.78128 -8.99106  43.03728  1.000 84.95082  ? 518 GLY   A CA  1 
ATOM   3725 C  C   . GLY   A 1 518 ? 45.25139 -8.71814  44.44874  1.000 85.57790  ? 518 GLY   A C   1 
ATOM   3726 O  O   . GLY   A 1 518 ? 44.86370 -9.39721  45.39944  1.000 82.73986  ? 518 GLY   A O   1 
ATOM   3727 N  N   . GLU   A 1 519 ? 46.09317 -7.69770  44.57683  1.000 87.68407  ? 519 GLU   A N   1 
ATOM   3728 C  CA  . GLU   A 1 519 ? 46.56539 -7.27341  45.88596  1.000 90.46702  ? 519 GLU   A CA  1 
ATOM   3729 C  C   . GLU   A 1 519 ? 45.52073 -6.39655  46.56400  1.000 90.76330  ? 519 GLU   A C   1 
ATOM   3730 O  O   . GLU   A 1 519 ? 44.89114 -5.54858  45.92502  1.000 95.01886  ? 519 GLU   A O   1 
ATOM   3731 C  CB  . GLU   A 1 519 ? 47.88631 -6.51339  45.76226  1.000 94.08211  ? 519 GLU   A CB  1 
ATOM   3732 C  CG  . GLU   A 1 519 ? 48.41455 -5.98751  47.08679  1.000 97.10172  ? 519 GLU   A CG  1 
ATOM   3733 C  CD  . GLU   A 1 519 ? 49.40994 -4.85979  46.91460  1.000 97.36602  ? 519 GLU   A CD  1 
ATOM   3734 O  OE1 . GLU   A 1 519 ? 50.45700 -5.07915  46.27093  1.000 93.87637  ? 519 GLU   A OE1 1 
ATOM   3735 O  OE2 . GLU   A 1 519 ? 49.13837 -3.74878  47.41710  1.000 95.37758  ? 519 GLU   A OE2 1 
ATOM   3736 N  N   . ALA   A 1 520 ? 45.33482 -6.61167  47.86476  1.000 83.79551  ? 520 ALA   A N   1 
ATOM   3737 C  CA  . ALA   A 1 520 ? 44.38897 -5.80887  48.62746  1.000 91.71885  ? 520 ALA   A CA  1 
ATOM   3738 C  C   . ALA   A 1 520 ? 44.83141 -4.35127  48.65442  1.000 103.83783 ? 520 ALA   A C   1 
ATOM   3739 O  O   . ALA   A 1 520 ? 45.96162 -4.03836  49.03968  1.000 113.18621 ? 520 ALA   A O   1 
ATOM   3740 C  CB  . ALA   A 1 520 ? 44.26139 -6.35361  50.04979  1.000 88.93714  ? 520 ALA   A CB  1 
ATOM   3741 N  N   . GLY   A 1 521 ? 43.93664 -3.45943  48.23692  1.000 94.50439  ? 521 GLY   A N   1 
ATOM   3742 C  CA  . GLY   A 1 521 ? 44.24857 -2.04487  48.18985  1.000 97.37353  ? 521 GLY   A CA  1 
ATOM   3743 C  C   . GLY   A 1 521 ? 43.92813 -1.41201  46.85194  1.000 105.76539 ? 521 GLY   A C   1 
ATOM   3744 O  O   . GLY   A 1 521 ? 43.45170 -0.27423  46.79441  1.000 102.96597 ? 521 GLY   A O   1 
ATOM   3745 N  N   . GLY   A 1 522 ? 44.18708 -2.13977  45.76752  1.000 108.40283 ? 522 GLY   A N   1 
ATOM   3746 C  CA  . GLY   A 1 522 ? 43.88619 -1.64734  44.43760  1.000 112.67053 ? 522 GLY   A CA  1 
ATOM   3747 C  C   . GLY   A 1 522 ? 44.73622 -2.26916  43.34851  1.000 102.81543 ? 522 GLY   A C   1 
ATOM   3748 O  O   . GLY   A 1 522 ? 44.39147 -2.19398  42.16499  1.000 98.39427  ? 522 GLY   A O   1 
ATOM   3749 N  N   . ARG   A 1 523 ? 45.84813 -2.89011  43.73486  1.000 91.13172  ? 523 ARG   A N   1 
ATOM   3750 C  CA  . ARG   A 1 523 ? 46.76175 -3.46776  42.75813  1.000 84.94539  ? 523 ARG   A CA  1 
ATOM   3751 C  C   . ARG   A 1 523 ? 46.20467 -4.77858  42.21642  1.000 88.17653  ? 523 ARG   A C   1 
ATOM   3752 O  O   . ARG   A 1 523 ? 45.80283 -5.65993  42.98196  1.000 92.83670  ? 523 ARG   A O   1 
ATOM   3753 C  CB  . ARG   A 1 523 ? 48.13544 -3.69587  43.38844  1.000 89.51810  ? 523 ARG   A CB  1 
ATOM   3754 C  CG  . ARG   A 1 523 ? 49.20421 -4.16057  42.40821  1.000 91.80236  ? 523 ARG   A CG  1 
ATOM   3755 C  CD  . ARG   A 1 523 ? 50.54440 -4.36624  43.10290  1.000 94.03185  ? 523 ARG   A CD  1 
ATOM   3756 N  NE  . ARG   A 1 523 ? 50.88834 -3.23801  43.96042  1.000 104.28846 ? 523 ARG   A NE  1 
ATOM   3757 C  CZ  . ARG   A 1 523 ? 51.49852 -2.13633  43.54504  1.000 100.89422 ? 523 ARG   A CZ  1 
ATOM   3758 N  NH1 . ARG   A 1 523 ? 51.87418 -1.98685  42.28527  1.000 92.20805  ? 523 ARG   A NH1 1 
ATOM   3759 N  NH2 . ARG   A 1 523 ? 51.73190 -1.15705  44.41447  1.000 94.22385  ? 523 ARG   A NH2 1 
ATOM   3760 N  N   . THR   A 1 524 ? 46.17981 -4.90484  40.89327  1.000 85.02688  ? 524 THR   A N   1 
ATOM   3761 C  CA  . THR   A 1 524 ? 45.73518 -6.11804  40.22188  1.000 81.60822  ? 524 THR   A CA  1 
ATOM   3762 C  C   . THR   A 1 524 ? 46.94498 -6.82942  39.63425  1.000 81.55137  ? 524 THR   A C   1 
ATOM   3763 O  O   . THR   A 1 524 ? 47.71918 -6.22877  38.88196  1.000 78.14269  ? 524 THR   A O   1 
ATOM   3764 C  CB  . THR   A 1 524 ? 44.71834 -5.80220  39.12370  1.000 78.21169  ? 524 THR   A CB  1 
ATOM   3765 O  OG1 . THR   A 1 524 ? 43.53952 -5.23792  39.71133  1.000 72.49020  ? 524 THR   A OG1 1 
ATOM   3766 C  CG2 . THR   A 1 524 ? 44.34653 -7.06753  38.36549  1.000 79.78266  ? 524 THR   A CG2 1 
ATOM   3767 N  N   . LEU   A 1 525 ? 47.10633 -8.10499  39.97758  1.000 84.65037  ? 525 LEU   A N   1 
ATOM   3768 C  CA  . LEU   A 1 525 ? 48.29761 -8.83922  39.57208  1.000 84.08926  ? 525 LEU   A CA  1 
ATOM   3769 C  C   . LEU   A 1 525 ? 48.08105 -9.62463  38.28292  1.000 81.71970  ? 525 LEU   A C   1 
ATOM   3770 O  O   . LEU   A 1 525 ? 48.86695 -9.50013  37.33876  1.000 80.43158  ? 525 LEU   A O   1 
ATOM   3771 C  CB  . LEU   A 1 525 ? 48.74073 -9.77767  40.69825  1.000 87.02482  ? 525 LEU   A CB  1 
ATOM   3772 C  CG  . LEU   A 1 525 ? 48.91165 -9.14308  42.08098  1.000 93.79318  ? 525 LEU   A CG  1 
ATOM   3773 C  CD1 . LEU   A 1 525 ? 49.35153 -10.18815 43.09393  1.000 99.40773  ? 525 LEU   A CD1 1 
ATOM   3774 C  CD2 . LEU   A 1 525 ? 49.89784 -7.98188  42.03743  1.000 87.16187  ? 525 LEU   A CD2 1 
ATOM   3775 N  N   . PHE   A 1 526 ? 47.02431 -10.43090 38.22291  1.000 85.09810  ? 526 PHE   A N   1 
ATOM   3776 C  CA  . PHE   A 1 526 ? 46.80373 -11.27872 37.05963  1.000 85.26278  ? 526 PHE   A CA  1 
ATOM   3777 C  C   . PHE   A 1 526 ? 45.31014 -11.44936 36.82533  1.000 86.96340  ? 526 PHE   A C   1 
ATOM   3778 O  O   . PHE   A 1 526 ? 44.50908 -11.36017 37.75678  1.000 87.25623  ? 526 PHE   A O   1 
ATOM   3779 C  CB  . PHE   A 1 526 ? 47.48175 -12.64410 37.23454  1.000 86.05905  ? 526 PHE   A CB  1 
ATOM   3780 C  CG  . PHE   A 1 526 ? 47.45225 -13.50023 36.00153  1.000 87.77529  ? 526 PHE   A CG  1 
ATOM   3781 C  CD1 . PHE   A 1 526 ? 48.04934 -13.06841 34.82930  1.000 89.38222  ? 526 PHE   A CD1 1 
ATOM   3782 C  CD2 . PHE   A 1 526 ? 46.83902 -14.74169 36.01784  1.000 89.29256  ? 526 PHE   A CD2 1 
ATOM   3783 C  CE1 . PHE   A 1 526 ? 48.02555 -13.85283 33.69432  1.000 87.94420  ? 526 PHE   A CE1 1 
ATOM   3784 C  CE2 . PHE   A 1 526 ? 46.81567 -15.53165 34.88595  1.000 90.60856  ? 526 PHE   A CE2 1 
ATOM   3785 C  CZ  . PHE   A 1 526 ? 47.40926 -15.08634 33.72325  1.000 90.25141  ? 526 PHE   A CZ  1 
ATOM   3786 N  N   . ARG   A 1 527 ? 44.94488 -11.70061 35.56945  1.000 88.14031  ? 527 ARG   A N   1 
ATOM   3787 C  CA  . ARG   A 1 527 ? 43.55207 -11.90412 35.19651  1.000 84.63104  ? 527 ARG   A CA  1 
ATOM   3788 C  C   . ARG   A 1 527 ? 43.48805 -12.85848 34.01468  1.000 79.32222  ? 527 ARG   A C   1 
ATOM   3789 O  O   . ARG   A 1 527 ? 44.26582 -12.72741 33.06563  1.000 76.34795  ? 527 ARG   A O   1 
ATOM   3790 C  CB  . ARG   A 1 527 ? 42.86376 -10.58378 34.83251  1.000 81.22573  ? 527 ARG   A CB  1 
ATOM   3791 C  CG  . ARG   A 1 527 ? 41.41434 -10.75263 34.40777  1.000 75.60041  ? 527 ARG   A CG  1 
ATOM   3792 C  CD  . ARG   A 1 527 ? 41.00462 -9.70672  33.38972  1.000 67.20289  ? 527 ARG   A CD  1 
ATOM   3793 N  NE  . ARG   A 1 527 ? 39.64282 -9.92273  32.91700  1.000 68.70656  ? 527 ARG   A NE  1 
ATOM   3794 C  CZ  . ARG   A 1 527 ? 39.30888 -10.77902 31.96113  1.000 73.28654  ? 527 ARG   A CZ  1 
ATOM   3795 N  NH1 . ARG   A 1 527 ? 40.21696 -11.52401 31.35177  1.000 74.46682  ? 527 ARG   A NH1 1 
ATOM   3796 N  NH2 . ARG   A 1 527 ? 38.03148 -10.89089 31.60785  1.000 75.58936  ? 527 ARG   A NH2 1 
ATOM   3797 N  N   . LEU   A 1 528 ? 42.55722 -13.80909 34.07254  1.000 78.37444  ? 528 LEU   A N   1 
ATOM   3798 C  CA  . LEU   A 1 528 ? 42.38345 -14.75066 32.97200  1.000 80.33065  ? 528 LEU   A CA  1 
ATOM   3799 C  C   . LEU   A 1 528 ? 41.04795 -15.45540 33.14155  1.000 74.74224  ? 528 LEU   A C   1 
ATOM   3800 O  O   . LEU   A 1 528 ? 40.51687 -15.54780 34.24870  1.000 71.13246  ? 528 LEU   A O   1 
ATOM   3801 C  CB  . LEU   A 1 528 ? 43.52316 -15.77745 32.91084  1.000 81.21671  ? 528 LEU   A CB  1 
ATOM   3802 C  CG  . LEU   A 1 528 ? 43.44401 -17.00497 33.82687  1.000 81.15834  ? 528 LEU   A CG  1 
ATOM   3803 C  CD1 . LEU   A 1 528 ? 44.54765 -17.99563 33.48475  1.000 83.74542  ? 528 LEU   A CD1 1 
ATOM   3804 C  CD2 . LEU   A 1 528 ? 43.50430 -16.62666 35.30267  1.000 78.22425  ? 528 LEU   A CD2 1 
ATOM   3805 N  N   . LEU   A 1 529 ? 40.51241 -15.95441 32.03248  1.000 73.87342  ? 529 LEU   A N   1 
ATOM   3806 C  CA  . LEU   A 1 529 ? 39.32427 -16.78616 32.12189  1.000 80.84126  ? 529 LEU   A CA  1 
ATOM   3807 C  C   . LEU   A 1 529 ? 39.69621 -18.16953 32.64995  1.000 85.47335  ? 529 LEU   A C   1 
ATOM   3808 O  O   . LEU   A 1 529 ? 40.86099 -18.57693 32.63429  1.000 87.51874  ? 529 LEU   A O   1 
ATOM   3809 C  CB  . LEU   A 1 529 ? 38.63468 -16.89757 30.76191  1.000 79.70486  ? 529 LEU   A CB  1 
ATOM   3810 C  CG  . LEU   A 1 529 ? 38.20220 -15.58327 30.10727  1.000 74.51709  ? 529 LEU   A CG  1 
ATOM   3811 C  CD1 . LEU   A 1 529 ? 37.28956 -15.84990 28.91846  1.000 81.55906  ? 529 LEU   A CD1 1 
ATOM   3812 C  CD2 . LEU   A 1 529 ? 37.52714 -14.66297 31.11461  1.000 69.22157  ? 529 LEU   A CD2 1 
ATOM   3813 N  N   . CYS   A 1 530 ? 38.68364 -18.89317 33.13126  1.000 76.04732  ? 530 CYS   A N   1 
ATOM   3814 C  CA  . CYS   A 1 530 ? 38.92393 -20.20077 33.73455  1.000 73.41722  ? 530 CYS   A CA  1 
ATOM   3815 C  C   . CYS   A 1 530 ? 39.53355 -21.16621 32.72357  1.000 84.81580  ? 530 CYS   A C   1 
ATOM   3816 O  O   . CYS   A 1 530 ? 40.62790 -21.70384 32.93548  1.000 91.85939  ? 530 CYS   A O   1 
ATOM   3817 C  CB  . CYS   A 1 530 ? 37.61832 -20.75802 34.30525  1.000 78.66762  ? 530 CYS   A CB  1 
ATOM   3818 S  SG  . CYS   A 1 530 ? 37.81438 -22.23401 35.33053  1.000 78.46644  ? 530 CYS   A SG  1 
ATOM   3819 N  N   . ARG   A 1 531 ? 38.84070 -21.38177 31.60152  1.000 85.56765  ? 531 ARG   A N   1 
ATOM   3820 C  CA  . ARG   A 1 531 ? 39.33959 -22.27748 30.56328  1.000 86.33174  ? 531 ARG   A CA  1 
ATOM   3821 C  C   . ARG   A 1 531 ? 40.69978 -21.85003 30.02765  1.000 87.91348  ? 531 ARG   A C   1 
ATOM   3822 O  O   . ARG   A 1 531 ? 41.42384 -22.68328 29.47194  1.000 86.52014  ? 531 ARG   A O   1 
ATOM   3823 C  CB  . ARG   A 1 531 ? 38.33548 -22.35528 29.41294  1.000 87.84918  ? 531 ARG   A CB  1 
ATOM   3824 C  CG  . ARG   A 1 531 ? 37.99435 -21.00305 28.80956  1.000 89.15406  ? 531 ARG   A CG  1 
ATOM   3825 C  CD  . ARG   A 1 531 ? 37.17382 -21.14687 27.53997  1.000 93.85132  ? 531 ARG   A CD  1 
ATOM   3826 N  NE  . ARG   A 1 531 ? 36.78381 -19.84990 27.00028  1.000 93.33292  ? 531 ARG   A NE  1 
ATOM   3827 C  CZ  . ARG   A 1 531 ? 35.62466 -19.25506 27.24644  1.000 92.12770  ? 531 ARG   A CZ  1 
ATOM   3828 N  NH1 . ARG   A 1 531 ? 34.70531 -19.82223 28.01047  1.000 90.76249  ? 531 ARG   A NH1 1 
ATOM   3829 N  NH2 . ARG   A 1 531 ? 35.38100 -18.06204 26.71139  1.000 84.35038  ? 531 ARG   A NH2 1 
ATOM   3830 N  N   . ASP   A 1 532 ? 41.06454 -20.57648 30.18224  1.000 92.39487  ? 532 ASP   A N   1 
ATOM   3831 C  CA  . ASP   A 1 532 ? 42.36287 -20.09020 29.73201  1.000 97.33495  ? 532 ASP   A CA  1 
ATOM   3832 C  C   . ASP   A 1 532 ? 43.51636 -20.58047 30.59681  1.000 99.33484  ? 532 ASP   A C   1 
ATOM   3833 O  O   . ASP   A 1 532 ? 44.67105 -20.27361 30.27849  1.000 96.65086  ? 532 ASP   A O   1 
ATOM   3834 C  CB  . ASP   A 1 532 ? 42.36477 -18.56052 29.69414  1.000 101.00189 ? 532 ASP   A CB  1 
ATOM   3835 C  CG  . ASP   A 1 532 ? 41.30951 -17.99887 28.76229  1.000 100.25582 ? 532 ASP   A CG  1 
ATOM   3836 O  OD1 . ASP   A 1 532 ? 40.60646 -18.79685 28.10670  1.000 92.13135  ? 532 ASP   A OD1 1 
ATOM   3837 O  OD2 . ASP   A 1 532 ? 41.18213 -16.75839 28.68728  1.000 96.36584  ? 532 ASP   A OD2 1 
ATOM   3838 N  N   . SER   A 1 533 ? 43.24454 -21.32569 31.67242  1.000 102.64174 ? 533 SER   A N   1 
ATOM   3839 C  CA  . SER   A 1 533 ? 44.32320 -21.82570 32.51762  1.000 100.11307 ? 533 SER   A CA  1 
ATOM   3840 C  C   . SER   A 1 533 ? 45.18861 -22.86023 31.80853  1.000 104.13175 ? 533 SER   A C   1 
ATOM   3841 O  O   . SER   A 1 533 ? 46.30648 -23.12845 32.26179  1.000 102.13880 ? 533 SER   A O   1 
ATOM   3842 C  CB  . SER   A 1 533 ? 43.75170 -22.42319 33.80452  1.000 90.09729  ? 533 SER   A CB  1 
ATOM   3843 O  OG  . SER   A 1 533 ? 43.06379 -21.44341 34.56196  1.000 85.56531  ? 533 SER   A OG  1 
ATOM   3844 N  N   . GLY   A 1 534 ? 44.70330 -23.44246 30.70949  1.000 103.32730 ? 534 GLY   A N   1 
ATOM   3845 C  CA  . GLY   A 1 534 ? 45.46879 -24.45189 29.99954  1.000 97.27548  ? 534 GLY   A CA  1 
ATOM   3846 C  C   . GLY   A 1 534 ? 46.61620 -23.90221 29.17856  1.000 100.29746 ? 534 GLY   A C   1 
ATOM   3847 O  O   . GLY   A 1 534 ? 47.48956 -24.67163 28.76407  1.000 102.33754 ? 534 GLY   A O   1 
ATOM   3848 N  N   . GLY   A 1 535 ? 46.63488 -22.59507 28.93229  1.000 107.53395 ? 535 GLY   A N   1 
ATOM   3849 C  CA  . GLY   A 1 535 ? 47.71523 -22.01064 28.15707  1.000 115.38869 ? 535 GLY   A CA  1 
ATOM   3850 C  C   . GLY   A 1 535 ? 49.02671 -22.03595 28.92383  1.000 113.48654 ? 535 GLY   A C   1 
ATOM   3851 O  O   . GLY   A 1 535 ? 49.06645 -21.83454 30.13825  1.000 109.76930 ? 535 GLY   A O   1 
ATOM   3852 N  N   . GLU   A 1 536 ? 50.11730 -22.28747 28.19376  1.000 117.86363 ? 536 GLU   A N   1 
ATOM   3853 C  CA  . GLU   A 1 536 ? 51.42812 -22.39082 28.82957  1.000 113.40555 ? 536 GLU   A CA  1 
ATOM   3854 C  C   . GLU   A 1 536 ? 51.85652 -21.06124 29.43767  1.000 103.25657 ? 536 GLU   A C   1 
ATOM   3855 O  O   . GLU   A 1 536 ? 52.40958 -21.02523 30.54371  1.000 100.13368 ? 536 GLU   A O   1 
ATOM   3856 C  CB  . GLU   A 1 536 ? 52.46979 -22.87509 27.81915  1.000 116.70905 ? 536 GLU   A CB  1 
ATOM   3857 C  CG  . GLU   A 1 536 ? 52.15795 -24.21921 27.17409  1.000 124.11951 ? 536 GLU   A CG  1 
ATOM   3858 C  CD  . GLU   A 1 536 ? 51.28249 -24.09321 25.94055  1.000 125.53600 ? 536 GLU   A CD  1 
ATOM   3859 O  OE1 . GLU   A 1 536 ? 50.67887 -23.01807 25.74093  1.000 122.30746 ? 536 GLU   A OE1 1 
ATOM   3860 O  OE2 . GLU   A 1 536 ? 51.20384 -25.06965 25.16565  1.000 123.25674 ? 536 GLU   A OE2 1 
ATOM   3861 N  N   . THR   A 1 537 ? 51.61508 -19.95740 28.72731  1.000 104.50323 ? 537 THR   A N   1 
ATOM   3862 C  CA  . THR   A 1 537 ? 51.95177 -18.64248 29.26389  1.000 106.47979 ? 537 THR   A CA  1 
ATOM   3863 C  C   . THR   A 1 537 ? 51.12410 -18.33630 30.50637  1.000 106.18928 ? 537 THR   A C   1 
ATOM   3864 O  O   . THR   A 1 537 ? 51.65607 -17.88655 31.53074  1.000 103.70346 ? 537 THR   A O   1 
ATOM   3865 C  CB  . THR   A 1 537 ? 51.73685 -17.57037 28.19473  1.000 100.95744 ? 537 THR   A CB  1 
ATOM   3866 O  OG1 . THR   A 1 537 ? 52.33140 -17.99629 26.96260  1.000 99.03649  ? 537 THR   A OG1 1 
ATOM   3867 C  CG2 . THR   A 1 537 ? 52.36916 -16.25579 28.62444  1.000 93.65163  ? 537 THR   A CG2 1 
ATOM   3868 N  N   . GLU   A 1 538 ? 49.81165 -18.57549 30.43022  1.000 107.55316 ? 538 GLU   A N   1 
ATOM   3869 C  CA  . GLU   A 1 538 ? 48.95964 -18.40369 31.60111  1.000 103.30212 ? 538 GLU   A CA  1 
ATOM   3870 C  C   . GLU   A 1 538 ? 49.37430 -19.34551 32.72296  1.000 101.34583 ? 538 GLU   A C   1 
ATOM   3871 O  O   . GLU   A 1 538 ? 49.34168 -18.96964 33.89818  1.000 98.16354  ? 538 GLU   A O   1 
ATOM   3872 C  CB  . GLU   A 1 538 ? 47.49238 -18.62901 31.23103  1.000 103.39513 ? 538 GLU   A CB  1 
ATOM   3873 C  CG  . GLU   A 1 538 ? 46.88698 -17.56081 30.33088  1.000 99.32248  ? 538 GLU   A CG  1 
ATOM   3874 C  CD  . GLU   A 1 538 ? 47.07481 -17.85519 28.85480  1.000 101.26086 ? 538 GLU   A CD  1 
ATOM   3875 O  OE1 . GLU   A 1 538 ? 48.01801 -18.59526 28.50500  1.000 101.46465 ? 538 GLU   A OE1 1 
ATOM   3876 O  OE2 . GLU   A 1 538 ? 46.27086 -17.35043 28.04317  1.000 104.88142 ? 538 GLU   A OE2 1 
ATOM   3877 N  N   . SER   A 1 539 ? 49.78115 -20.57091 32.37976  1.000 105.23779 ? 539 SER   A N   1 
ATOM   3878 C  CA  . SER   A 1 539 ? 50.19525 -21.52403 33.40562  1.000 100.80787 ? 539 SER   A CA  1 
ATOM   3879 C  C   . SER   A 1 539 ? 51.44356 -21.04504 34.13599  1.000 100.26304 ? 539 SER   A C   1 
ATOM   3880 O  O   . SER   A 1 539 ? 51.53225 -21.15390 35.36429  1.000 97.31806  ? 539 SER   A O   1 
ATOM   3881 C  CB  . SER   A 1 539 ? 50.43294 -22.89996 32.78372  1.000 97.68200  ? 539 SER   A CB  1 
ATOM   3882 O  OG  . SER   A 1 539 ? 49.23808 -23.42105 32.22838  1.000 95.96151  ? 539 SER   A OG  1 
ATOM   3883 N  N   . MET   A 1 540 ? 52.41788 -20.50537 33.39982  1.000 101.09277 ? 540 MET   A N   1 
ATOM   3884 C  CA  . MET   A 1 540 ? 53.62563 -19.99988 34.04502  1.000 102.98093 ? 540 MET   A CA  1 
ATOM   3885 C  C   . MET   A 1 540 ? 53.32867 -18.75465 34.87150  1.000 101.62828 ? 540 MET   A C   1 
ATOM   3886 O  O   . MET   A 1 540 ? 53.84924 -18.60103 35.98455  1.000 107.06952 ? 540 MET   A O   1 
ATOM   3887 C  CB  . MET   A 1 540 ? 54.70208 -19.70535 33.00079  1.000 110.77603 ? 540 MET   A CB  1 
ATOM   3888 C  CG  . MET   A 1 540 ? 56.07707 -19.43644 33.59643  1.000 122.75584 ? 540 MET   A CG  1 
ATOM   3889 S  SD  . MET   A 1 540 ? 57.29335 -18.90651 32.37505  1.000 131.63479 ? 540 MET   A SD  1 
ATOM   3890 C  CE  . MET   A 1 540 ? 56.66301 -17.28430 31.95247  1.000 104.75937 ? 540 MET   A CE  1 
ATOM   3891 N  N   . LEU   A 1 541 ? 52.49101 -17.85420 34.34943  1.000 95.69517  ? 541 LEU   A N   1 
ATOM   3892 C  CA  . LEU   A 1 541 ? 52.14541 -16.66160 35.11574  1.000 98.88396  ? 541 LEU   A CA  1 
ATOM   3893 C  C   . LEU   A 1 541 ? 51.34513 -17.01174 36.36554  1.000 98.33868  ? 541 LEU   A C   1 
ATOM   3894 O  O   . LEU   A 1 541 ? 51.42674 -16.29745 37.36995  1.000 94.34193  ? 541 LEU   A O   1 
ATOM   3895 C  CB  . LEU   A 1 541 ? 51.38373 -15.66875 34.23601  1.000 99.33280  ? 541 LEU   A CB  1 
ATOM   3896 C  CG  . LEU   A 1 541 ? 52.24127 -14.58768 33.56357  1.000 100.02115 ? 541 LEU   A CG  1 
ATOM   3897 C  CD1 . LEU   A 1 541 ? 53.36660 -15.19462 32.73454  1.000 97.58451  ? 541 LEU   A CD1 1 
ATOM   3898 C  CD2 . LEU   A 1 541 ? 51.38811 -13.66456 32.70691  1.000 93.82301  ? 541 LEU   A CD2 1 
ATOM   3899 N  N   . LEU   A 1 542 ? 50.58916 -18.11185 36.33414  1.000 101.08680 ? 542 LEU   A N   1 
ATOM   3900 C  CA  . LEU   A 1 542 ? 49.91906 -18.58911 37.54001  1.000 93.94938  ? 542 LEU   A CA  1 
ATOM   3901 C  C   . LEU   A 1 542 ? 50.92275 -19.18252 38.52035  1.000 92.83454  ? 542 LEU   A C   1 
ATOM   3902 O  O   . LEU   A 1 542 ? 50.90887 -18.85706 39.71315  1.000 89.40307  ? 542 LEU   A O   1 
ATOM   3903 C  CB  . LEU   A 1 542 ? 48.85219 -19.62199 37.17460  1.000 93.46121  ? 542 LEU   A CB  1 
ATOM   3904 C  CG  . LEU   A 1 542 ? 47.57626 -19.12768 36.49261  1.000 92.44189  ? 542 LEU   A CG  1 
ATOM   3905 C  CD1 . LEU   A 1 542 ? 46.76551 -20.30486 35.97495  1.000 83.61740  ? 542 LEU   A CD1 1 
ATOM   3906 C  CD2 . LEU   A 1 542 ? 46.75222 -18.28989 37.45060  1.000 83.38920  ? 542 LEU   A CD2 1 
ATOM   3907 N  N   . ASN   A 1 543 ? 51.80316 -20.06053 38.02827  1.000 98.48070  ? 543 ASN   A N   1 
ATOM   3908 C  CA  . ASN   A 1 543 ? 52.86163 -20.62747 38.85796  1.000 102.24244 ? 543 ASN   A CA  1 
ATOM   3909 C  C   . ASN   A 1 543 ? 53.67519 -19.54380 39.55073  1.000 105.88763 ? 543 ASN   A C   1 
ATOM   3910 O  O   . ASN   A 1 543 ? 54.16349 -19.74727 40.66658  1.000 112.95572 ? 543 ASN   A O   1 
ATOM   3911 C  CB  . ASN   A 1 543 ? 53.77463 -21.50624 37.99939  1.000 97.68010  ? 543 ASN   A CB  1 
ATOM   3912 C  CG  . ASN   A 1 543 ? 54.48860 -22.57399 38.80432  1.000 104.19265 ? 543 ASN   A CG  1 
ATOM   3913 O  OD1 . ASN   A 1 543 ? 54.69328 -22.43242 40.00964  1.000 108.05803 ? 543 ASN   A OD1 1 
ATOM   3914 N  ND2 . ASN   A 1 543 ? 54.87216 -23.65506 38.13583  1.000 101.48375 ? 543 ASN   A ND2 1 
ATOM   3915 N  N   . GLU   A 1 544 ? 53.83139 -18.38798 38.91056  1.000 102.06324 ? 544 GLU   A N   1 
ATOM   3916 C  CA  . GLU   A 1 544 ? 54.55696 -17.29617 39.54972  1.000 107.91735 ? 544 GLU   A CA  1 
ATOM   3917 C  C   . GLU   A 1 544 ? 53.65914 -16.44554 40.44391  1.000 109.03727 ? 544 GLU   A C   1 
ATOM   3918 O  O   . GLU   A 1 544 ? 54.12642 -15.92815 41.46584  1.000 111.65735 ? 544 GLU   A O   1 
ATOM   3919 C  CB  . GLU   A 1 544 ? 55.22414 -16.41312 38.49263  1.000 110.87588 ? 544 GLU   A CB  1 
ATOM   3920 C  CG  . GLU   A 1 544 ? 56.25586 -17.12560 37.63204  1.000 114.66677 ? 544 GLU   A CG  1 
ATOM   3921 C  CD  . GLU   A 1 544 ? 56.87204 -16.19985 36.60459  1.000 120.27206 ? 544 GLU   A CD  1 
ATOM   3922 O  OE1 . GLU   A 1 544 ? 56.68976 -14.97154 36.73795  1.000 113.63867 ? 544 GLU   A OE1 1 
ATOM   3923 O  OE2 . GLU   A 1 544 ? 57.53097 -16.69333 35.66488  1.000 124.87985 ? 544 GLU   A OE2 1 
ATOM   3924 N  N   . THR   A 1 545 ? 52.37980 -16.30198 40.09291  1.000 104.05678 ? 545 THR   A N   1 
ATOM   3925 C  CA  . THR   A 1 545 ? 51.49142 -15.35169 40.75049  1.000 93.05295  ? 545 THR   A CA  1 
ATOM   3926 C  C   . THR   A 1 545 ? 50.63950 -15.96505 41.85499  1.000 89.17794  ? 545 THR   A C   1 
ATOM   3927 O  O   . THR   A 1 545 ? 50.36568 -15.28600 42.85082  1.000 86.65188  ? 545 THR   A O   1 
ATOM   3928 C  CB  . THR   A 1 545 ? 50.56702 -14.69915 39.71420  1.000 91.57204  ? 545 THR   A CB  1 
ATOM   3929 O  OG1 . THR   A 1 545 ? 51.34100 -14.24159 38.59967  1.000 102.78541 ? 545 THR   A OG1 1 
ATOM   3930 C  CG2 . THR   A 1 545 ? 49.82043 -13.51394 40.31864  1.000 86.44897  ? 545 THR   A CG2 1 
ATOM   3931 N  N   . VAL   A 1 546 ? 50.21073 -17.21657 41.70700  1.000 91.07280  ? 546 VAL   A N   1 
ATOM   3932 C  CA  . VAL   A 1 546 ? 49.30056 -17.81717 42.69216  1.000 84.66320  ? 546 VAL   A CA  1 
ATOM   3933 C  C   . VAL   A 1 546 ? 49.97958 -17.85113 44.05719  1.000 81.56605  ? 546 VAL   A C   1 
ATOM   3934 O  O   . VAL   A 1 546 ? 51.10222 -18.38128 44.18023  1.000 84.07947  ? 546 VAL   A O   1 
ATOM   3935 C  CB  . VAL   A 1 546 ? 48.87834 -19.22937 42.25080  1.000 86.22417  ? 546 VAL   A CB  1 
ATOM   3936 C  CG1 . VAL   A 1 546 ? 48.10086 -19.91796 43.35804  1.000 80.19308  ? 546 VAL   A CG1 1 
ATOM   3937 C  CG2 . VAL   A 1 546 ? 48.04022 -19.15996 40.98420  1.000 86.75924  ? 546 VAL   A CG2 1 
ATOM   3938 N  N   . PRO   A 1 547 ? 49.36252 -17.30619 45.10302  1.000 75.17452  ? 547 PRO   A N   1 
ATOM   3939 C  CA  . PRO   A 1 547 ? 50.01414 -17.26882 46.41694  1.000 77.30404  ? 547 PRO   A CA  1 
ATOM   3940 C  C   . PRO   A 1 547 ? 50.09917 -18.65423 47.04102  1.000 85.46073  ? 547 PRO   A C   1 
ATOM   3941 O  O   . PRO   A 1 547 ? 49.47915 -19.61970 46.59154  1.000 90.56157  ? 547 PRO   A O   1 
ATOM   3942 C  CB  . PRO   A 1 547 ? 49.11172 -16.33973 47.23263  1.000 79.05563  ? 547 PRO   A CB  1 
ATOM   3943 C  CG  . PRO   A 1 547 ? 47.77383 -16.46101 46.58396  1.000 75.22217  ? 547 PRO   A CG  1 
ATOM   3944 C  CD  . PRO   A 1 547 ? 48.03958 -16.65854 45.11912  1.000 75.59969  ? 547 PRO   A CD  1 
ATOM   3945 N  N   . GLN   A 1 548 ? 50.88920 -18.73338 48.11497  1.000 86.94776  ? 548 GLN   A N   1 
ATOM   3946 C  CA  . GLN   A 1 548 ? 51.14272 -20.01833 48.76017  1.000 89.50420  ? 548 GLN   A CA  1 
ATOM   3947 C  C   . GLN   A 1 548 ? 49.88935 -20.56442 49.43454  1.000 87.85909  ? 548 GLN   A C   1 
ATOM   3948 O  O   . GLN   A 1 548 ? 49.65681 -21.78033 49.43283  1.000 88.78617  ? 548 GLN   A O   1 
ATOM   3949 C  CB  . GLN   A 1 548 ? 52.28073 -19.87881 49.77184  1.000 93.28172  ? 548 GLN   A CB  1 
ATOM   3950 C  CG  . GLN   A 1 548 ? 52.64166 -21.17298 50.48233  1.000 95.64011  ? 548 GLN   A CG  1 
ATOM   3951 C  CD  . GLN   A 1 548 ? 53.06984 -22.26381 49.52106  1.000 98.91217  ? 548 GLN   A CD  1 
ATOM   3952 O  OE1 . GLN   A 1 548 ? 53.96922 -22.06927 48.70320  1.000 95.47528  ? 548 GLN   A OE1 1 
ATOM   3953 N  NE2 . GLN   A 1 548 ? 52.42093 -23.41889 49.61046  1.000 106.34885 ? 548 GLN   A NE2 1 
ATOM   3954 N  N   . TRP   A 1 549 ? 49.06882 -19.68557 50.01601  1.000 82.08915  ? 549 TRP   A N   1 
ATOM   3955 C  CA  . TRP   A 1 549 ? 47.85423 -20.13177 50.68798  1.000 76.00149  ? 549 TRP   A CA  1 
ATOM   3956 C  C   . TRP   A 1 549 ? 46.80456 -20.65869 49.71910  1.000 78.71932  ? 549 TRP   A C   1 
ATOM   3957 O  O   . TRP   A 1 549 ? 45.78514 -21.19296 50.16867  1.000 80.67825  ? 549 TRP   A O   1 
ATOM   3958 C  CB  . TRP   A 1 549 ? 47.26568 -18.99688 51.52820  1.000 76.41917  ? 549 TRP   A CB  1 
ATOM   3959 C  CG  . TRP   A 1 549 ? 46.74773 -17.83848 50.73090  1.000 83.52683  ? 549 TRP   A CG  1 
ATOM   3960 C  CD1 . TRP   A 1 549 ? 47.45690 -16.75376 50.30439  1.000 88.67934  ? 549 TRP   A CD1 1 
ATOM   3961 C  CD2 . TRP   A 1 549 ? 45.40170 -17.63998 50.28062  1.000 81.81507  ? 549 TRP   A CD2 1 
ATOM   3962 N  NE1 . TRP   A 1 549 ? 46.63782 -15.89529 49.61106  1.000 87.68284  ? 549 TRP   A NE1 1 
ATOM   3963 C  CE2 . TRP   A 1 549 ? 45.37122 -16.41681 49.58174  1.000 84.29213  ? 549 TRP   A CE2 1 
ATOM   3964 C  CE3 . TRP   A 1 549 ? 44.22054 -18.37895 50.39846  1.000 75.09140  ? 549 TRP   A CE3 1 
ATOM   3965 C  CZ2 . TRP   A 1 549 ? 44.20672 -15.91680 49.00240  1.000 77.34611  ? 549 TRP   A CZ2 1 
ATOM   3966 C  CZ3 . TRP   A 1 549 ? 43.06562 -17.88095 49.82230  1.000 71.33515  ? 549 TRP   A CZ3 1 
ATOM   3967 C  CH2 . TRP   A 1 549 ? 43.06727 -16.66191 49.13335  1.000 72.49292  ? 549 TRP   A CH2 1 
ATOM   3968 N  N   . VAL   A 1 550 ? 47.02645 -20.52365 48.41341  1.000 79.56404  ? 550 VAL   A N   1 
ATOM   3969 C  CA  . VAL   A 1 550 ? 46.15513 -21.11826 47.40764  1.000 78.98018  ? 550 VAL   A CA  1 
ATOM   3970 C  C   . VAL   A 1 550 ? 46.84342 -22.35830 46.85156  1.000 79.87468  ? 550 VAL   A C   1 
ATOM   3971 O  O   . VAL   A 1 550 ? 46.18611 -23.34392 46.49791  1.000 83.19621  ? 550 VAL   A O   1 
ATOM   3972 C  CB  . VAL   A 1 550 ? 45.81886 -20.10838 46.29413  1.000 78.95184  ? 550 VAL   A CB  1 
ATOM   3973 C  CG1 . VAL   A 1 550 ? 44.99624 -20.76681 45.19608  1.000 76.46088  ? 550 VAL   A CG1 1 
ATOM   3974 C  CG2 . VAL   A 1 550 ? 45.07647 -18.91358 46.87335  1.000 74.19798  ? 550 VAL   A CG2 1 
ATOM   3975 N  N   . ILE   A 1 551 ? 48.17667 -22.31979 46.78718  1.000 80.99080  ? 551 ILE   A N   1 
ATOM   3976 C  CA  . ILE   A 1 551 ? 48.93423 -23.45343 46.26483  1.000 84.97031  ? 551 ILE   A CA  1 
ATOM   3977 C  C   . ILE   A 1 551 ? 48.80106 -24.66142 47.18378  1.000 80.42476  ? 551 ILE   A C   1 
ATOM   3978 O  O   . ILE   A 1 551 ? 48.57995 -25.78744 46.72157  1.000 81.03131  ? 551 ILE   A O   1 
ATOM   3979 C  CB  . ILE   A 1 551 ? 50.40930 -23.06107 46.05880  1.000 89.37757  ? 551 ILE   A CB  1 
ATOM   3980 C  CG1 . ILE   A 1 551 ? 50.54844 -22.08986 44.88572  1.000 92.32935  ? 551 ILE   A CG1 1 
ATOM   3981 C  CG2 . ILE   A 1 551 ? 51.26851 -24.29640 45.83134  1.000 85.61325  ? 551 ILE   A CG2 1 
ATOM   3982 C  CD1 . ILE   A 1 551 ? 51.96770 -21.62014 44.64621  1.000 96.73440  ? 551 ILE   A CD1 1 
ATOM   3983 N  N   . ASP   A 1 552 ? 48.92366 -24.45158 48.49668  1.000 78.78515  ? 552 ASP   A N   1 
ATOM   3984 C  CA  . ASP   A 1 552 ? 48.90122 -25.57036 49.43352  1.000 84.87762  ? 552 ASP   A CA  1 
ATOM   3985 C  C   . ASP   A 1 552 ? 47.54853 -26.27078 49.49870  1.000 87.42756  ? 552 ASP   A C   1 
ATOM   3986 O  O   . ASP   A 1 552 ? 47.46474 -27.35783 50.08053  1.000 86.73336  ? 552 ASP   A O   1 
ATOM   3987 C  CB  . ASP   A 1 552 ? 49.30787 -25.09734 50.83139  1.000 87.16717  ? 552 ASP   A CB  1 
ATOM   3988 C  CG  . ASP   A 1 552 ? 48.32975 -24.10197 51.41781  1.000 96.21639  ? 552 ASP   A CG  1 
ATOM   3989 O  OD1 . ASP   A 1 552 ? 47.64766 -23.40901 50.63576  1.000 97.19645  ? 552 ASP   A OD1 1 
ATOM   3990 O  OD2 . ASP   A 1 552 ? 48.24158 -24.01271 52.66081  1.000 100.98758 ? 552 ASP   A OD2 1 
ATOM   3991 N  N   . ILE   A 1 553 ? 46.49920 -25.68802 48.92268  1.000 81.57327  ? 553 ILE   A N   1 
ATOM   3992 C  CA  . ILE   A 1 553 ? 45.18541 -26.31057 48.87289  1.000 79.50106  ? 553 ILE   A CA  1 
ATOM   3993 C  C   . ILE   A 1 553 ? 44.86362 -26.83485 47.47798  1.000 79.51955  ? 553 ILE   A C   1 
ATOM   3994 O  O   . ILE   A 1 553 ? 44.36394 -27.95299 47.33367  1.000 83.19614  ? 553 ILE   A O   1 
ATOM   3995 C  CB  . ILE   A 1 553 ? 44.09054 -25.33427 49.36406  1.000 73.78894  ? 553 ILE   A CB  1 
ATOM   3996 C  CG1 . ILE   A 1 553 ? 43.86120 -25.48532 50.87131  1.000 80.87028  ? 553 ILE   A CG1 1 
ATOM   3997 C  CG2 . ILE   A 1 553 ? 42.78037 -25.55406 48.61812  1.000 69.21216  ? 553 ILE   A CG2 1 
ATOM   3998 C  CD1 . ILE   A 1 553 ? 44.98219 -24.95502 51.73379  1.000 87.71889  ? 553 ILE   A CD1 1 
ATOM   3999 N  N   . THR   A 1 554 ? 45.15984 -26.05268 46.43745  1.000 78.70830  ? 554 THR   A N   1 
ATOM   4000 C  CA  . THR   A 1 554 ? 44.80470 -26.45133 45.08031  1.000 82.72964  ? 554 THR   A CA  1 
ATOM   4001 C  C   . THR   A 1 554 ? 45.83746 -27.38402 44.45922  1.000 91.56324  ? 554 THR   A C   1 
ATOM   4002 O  O   . THR   A 1 554 ? 45.47764 -28.24243 43.64574  1.000 99.65457  ? 554 THR   A O   1 
ATOM   4003 C  CB  . THR   A 1 554 ? 44.62583 -25.21331 44.19859  1.000 79.03182  ? 554 THR   A CB  1 
ATOM   4004 O  OG1 . THR   A 1 554 ? 45.83037 -24.43628 44.21100  1.000 86.63107  ? 554 THR   A OG1 1 
ATOM   4005 C  CG2 . THR   A 1 554 ? 43.47210 -24.35913 44.70636  1.000 73.83451  ? 554 THR   A CG2 1 
ATOM   4006 N  N   . VAL   A 1 555 ? 47.11107 -27.23672 44.82084  1.000 87.70853  ? 555 VAL   A N   1 
ATOM   4007 C  CA  . VAL   A 1 555 ? 48.17210 -28.05907 44.24927  1.000 86.71889  ? 555 VAL   A CA  1 
ATOM   4008 C  C   . VAL   A 1 555 ? 48.56452 -29.15069 45.23569  1.000 85.40689  ? 555 VAL   A C   1 
ATOM   4009 O  O   . VAL   A 1 555 ? 48.49565 -30.34346 44.91802  1.000 82.48019  ? 555 VAL   A O   1 
ATOM   4010 C  CB  . VAL   A 1 555 ? 49.39251 -27.20443 43.85967  1.000 87.96108  ? 555 VAL   A CB  1 
ATOM   4011 C  CG1 . VAL   A 1 555 ? 50.50276 -28.08429 43.30463  1.000 86.01049  ? 555 VAL   A CG1 1 
ATOM   4012 C  CG2 . VAL   A 1 555 ? 48.99350 -26.14037 42.84824  1.000 95.73188  ? 555 VAL   A CG2 1 
ATOM   4013 N  N   . ASP   A 1 556 ? 48.97763 -28.75099 46.44098  1.000 88.58423  ? 556 ASP   A N   1 
ATOM   4014 C  CA  . ASP   A 1 556 ? 49.43310 -29.72225 47.42895  1.000 92.57817  ? 556 ASP   A CA  1 
ATOM   4015 C  C   . ASP   A 1 556 ? 48.29081 -30.54686 48.00833  1.000 90.93962  ? 556 ASP   A C   1 
ATOM   4016 O  O   . ASP   A 1 556 ? 48.55096 -31.58387 48.62833  1.000 95.80913  ? 556 ASP   A O   1 
ATOM   4017 C  CB  . ASP   A 1 556 ? 50.18910 -29.01640 48.55686  1.000 89.75376  ? 556 ASP   A CB  1 
ATOM   4018 C  CG  . ASP   A 1 556 ? 51.41895 -28.27857 48.06257  1.000 89.26950  ? 556 ASP   A CG  1 
ATOM   4019 O  OD1 . ASP   A 1 556 ? 51.58999 -28.16631 46.83032  1.000 89.53504  ? 556 ASP   A OD1 1 
ATOM   4020 O  OD2 . ASP   A 1 556 ? 52.21577 -27.81378 48.90556  1.000 85.51814  ? 556 ASP   A OD2 1 
ATOM   4021 N  N   . LYS   A 1 557 ? 47.04207 -30.10823 47.82767  1.000 84.50264  ? 557 LYS   A N   1 
ATOM   4022 C  CA  . LYS   A 1 557 ? 45.86051 -30.85001 48.27435  1.000 82.37183  ? 557 LYS   A CA  1 
ATOM   4023 C  C   . LYS   A 1 557 ? 45.87236 -31.09247 49.78212  1.000 86.91387  ? 557 LYS   A C   1 
ATOM   4024 O  O   . LYS   A 1 557 ? 45.38209 -32.11873 50.25960  1.000 87.62402  ? 557 LYS   A O   1 
ATOM   4025 C  CB  . LYS   A 1 557 ? 45.72478 -32.17974 47.52446  1.000 90.89441  ? 557 LYS   A CB  1 
ATOM   4026 C  CG  . LYS   A 1 557 ? 45.62057 -32.04594 46.01167  1.000 90.40902  ? 557 LYS   A CG  1 
ATOM   4027 C  CD  . LYS   A 1 557 ? 44.18366 -31.82224 45.56827  1.000 87.78937  ? 557 LYS   A CD  1 
ATOM   4028 C  CE  . LYS   A 1 557 ? 44.08117 -31.72250 44.05426  1.000 83.87761  ? 557 LYS   A CE  1 
ATOM   4029 N  NZ  . LYS   A 1 557 ? 44.79566 -30.52696 43.52869  1.000 86.67428  ? 557 LYS   A NZ  1 
ATOM   4030 N  N   . ASN   A 1 558 ? 46.42776 -30.15499 50.54321  1.000 92.02656  ? 558 ASN   A N   1 
ATOM   4031 C  CA  . ASN   A 1 558 ? 46.52076 -30.29502 51.98755  1.000 98.58624  ? 558 ASN   A CA  1 
ATOM   4032 C  C   . ASN   A 1 558 ? 45.27405 -29.73577 52.66970  1.000 93.84863  ? 558 ASN   A C   1 
ATOM   4033 O  O   . ASN   A 1 558 ? 44.45091 -29.04806 52.06166  1.000 89.34677  ? 558 ASN   A O   1 
ATOM   4034 C  CB  . ASN   A 1 558 ? 47.77354 -29.59438 52.51489  1.000 98.09149  ? 558 ASN   A CB  1 
ATOM   4035 C  CG  . ASN   A 1 558 ? 49.05310 -30.27872 52.07702  1.000 102.90028 ? 558 ASN   A CG  1 
ATOM   4036 O  OD1 . ASN   A 1 558 ? 49.09086 -31.49640 51.90049  1.000 106.12357 ? 558 ASN   A OD1 1 
ATOM   4037 N  ND2 . ASN   A 1 558 ? 50.11221 -29.49671 51.90259  1.000 98.59371  ? 558 ASN   A ND2 1 
ATOM   4038 N  N   . MET   A 1 559 ? 45.14400 -30.04401 53.95686  1.000 97.08868  ? 559 MET   A N   1 
ATOM   4039 C  CA  . MET   A 1 559 ? 44.02744 -29.52866 54.73354  1.000 102.24006 ? 559 MET   A CA  1 
ATOM   4040 C  C   . MET   A 1 559 ? 44.22992 -28.04229 55.02025  1.000 101.65573 ? 559 MET   A C   1 
ATOM   4041 O  O   . MET   A 1 559 ? 45.36024 -27.60089 55.25128  1.000 110.91554 ? 559 MET   A O   1 
ATOM   4042 C  CB  . MET   A 1 559 ? 43.87990 -30.29970 56.04464  1.000 104.43086 ? 559 MET   A CB  1 
ATOM   4043 C  CG  . MET   A 1 559 ? 43.25284 -31.67500 55.88956  1.000 113.66974 ? 559 MET   A CG  1 
ATOM   4044 S  SD  . MET   A 1 559 ? 41.52464 -31.58725 55.38245  1.000 121.22518 ? 559 MET   A SD  1 
ATOM   4045 C  CE  . MET   A 1 559 ? 40.82397 -30.65400 56.74095  1.000 81.92621  ? 559 MET   A CE  1 
ATOM   4046 N  N   . PRO   A 1 560 ? 43.15799 -27.24597 55.00821  1.000 88.66238  ? 560 PRO   A N   1 
ATOM   4047 C  CA  . PRO   A 1 560 ? 43.32489 -25.79987 55.22022  1.000 86.02297  ? 560 PRO   A CA  1 
ATOM   4048 C  C   . PRO   A 1 560 ? 43.73851 -25.43462 56.63474  1.000 96.80886  ? 560 PRO   A C   1 
ATOM   4049 O  O   . PRO   A 1 560 ? 44.45929 -24.44457 56.81320  1.000 101.73882 ? 560 PRO   A O   1 
ATOM   4050 C  CB  . PRO   A 1 560 ? 41.93913 -25.23268 54.87901  1.000 79.00253  ? 560 PRO   A CB  1 
ATOM   4051 C  CG  . PRO   A 1 560 ? 41.24798 -26.31253 54.09743  1.000 66.75229  ? 560 PRO   A CG  1 
ATOM   4052 C  CD  . PRO   A 1 560 ? 41.77650 -27.59716 54.64409  1.000 80.06878  ? 560 PRO   A CD  1 
ATOM   4053 N  N   . LYS   A 1 561 ? 43.29223 -26.19231 57.64011  1.000 96.26746  ? 561 LYS   A N   1 
ATOM   4054 C  CA  . LYS   A 1 561 ? 43.56844 -25.91552 59.04832  1.000 97.68953  ? 561 LYS   A CA  1 
ATOM   4055 C  C   . LYS   A 1 561 ? 42.99756 -24.56851 59.48309  1.000 93.16982  ? 561 LYS   A C   1 
ATOM   4056 O  O   . LYS   A 1 561 ? 42.32590 -23.88752 58.70109  1.000 92.81684  ? 561 LYS   A O   1 
ATOM   4057 C  CB  . LYS   A 1 561 ? 45.07277 -25.98423 59.33137  1.000 95.11143  ? 561 LYS   A CB  1 
ATOM   4058 C  CG  . LYS   A 1 561 ? 45.61925 -27.40392 59.38862  1.000 99.25724  ? 561 LYS   A CG  1 
ATOM   4059 C  CD  . LYS   A 1 561 ? 46.66203 -27.65832 58.31285  1.000 100.47212 ? 561 LYS   A CD  1 
ATOM   4060 C  CE  . LYS   A 1 561 ? 47.13598 -29.10440 58.34329  1.000 99.86361  ? 561 LYS   A CE  1 
ATOM   4061 N  NZ  . LYS   A 1 561 ? 48.18668 -29.37059 57.32203  1.000 102.28900 ? 561 LYS   A NZ  1 
ATOM   4062 N  N   . PHE   A 1 562 ? 43.25424 -24.17831 60.72818  1.000 88.83590  ? 562 PHE   A N   1 
ATOM   4063 C  CA  . PHE   A 1 562 ? 42.60437 -23.02940 61.33944  1.000 91.22529  ? 562 PHE   A CA  1 
ATOM   4064 C  C   . PHE   A 1 562 ? 43.56915 -21.85447 61.46444  1.000 99.27038  ? 562 PHE   A C   1 
ATOM   4065 O  O   . PHE   A 1 562 ? 44.79036 -22.00551 61.36127  1.000 96.79157  ? 562 PHE   A O   1 
ATOM   4066 C  CB  . PHE   A 1 562 ? 42.04147 -23.40131 62.71662  1.000 89.06931  ? 562 PHE   A CB  1 
ATOM   4067 C  CG  . PHE   A 1 562 ? 40.98262 -22.45995 63.21493  1.000 97.59213  ? 562 PHE   A CG  1 
ATOM   4068 C  CD1 . PHE   A 1 562 ? 39.76561 -22.35724 62.56068  1.000 96.64069  ? 562 PHE   A CD1 1 
ATOM   4069 C  CD2 . PHE   A 1 562 ? 41.19856 -21.68643 64.34292  1.000 97.87632  ? 562 PHE   A CD2 1 
ATOM   4070 C  CE1 . PHE   A 1 562 ? 38.78724 -21.49306 63.01744  1.000 93.67694  ? 562 PHE   A CE1 1 
ATOM   4071 C  CE2 . PHE   A 1 562 ? 40.22430 -20.82223 64.80535  1.000 95.64534  ? 562 PHE   A CE2 1 
ATOM   4072 C  CZ  . PHE   A 1 562 ? 39.01707 -20.72540 64.14163  1.000 91.18037  ? 562 PHE   A CZ  1 
ATOM   4073 N  N   . ASN   A 1 563 ? 42.99196 -20.67432 61.68917  1.000 103.54568 ? 563 ASN   A N   1 
ATOM   4074 C  CA  . ASN   A 1 563 ? 43.73742 -19.42236 61.82820  1.000 100.13279 ? 563 ASN   A CA  1 
ATOM   4075 C  C   . ASN   A 1 563 ? 44.64271 -19.15753 60.62882  1.000 107.37584 ? 563 ASN   A C   1 
ATOM   4076 O  O   . ASN   A 1 563 ? 44.66514 -18.04998 60.09053  1.000 104.78340 ? 563 ASN   A O   1 
ATOM   4077 C  CB  . ASN   A 1 563 ? 44.56475 -19.42442 63.11788  1.000 98.93630  ? 563 ASN   A CB  1 
ATOM   4078 C  CG  . ASN   A 1 563 ? 43.70272 -19.36470 64.36365  1.000 97.27822  ? 563 ASN   A CG  1 
ATOM   4079 O  OD1 . ASN   A 1 563 ? 43.88211 -20.14823 65.29576  1.000 100.11865 ? 563 ASN   A OD1 1 
ATOM   4080 N  ND2 . ASN   A 1 563 ? 42.75582 -18.43286 64.38331  1.000 87.59196  ? 563 ASN   A ND2 1 
ATOM   4081 N  N   . GLY   B 2 4   ? 46.39755 32.61167  98.93618  1.000 89.51926  ? 87  GLY   B N   1 
ATOM   4082 C  CA  . GLY   B 2 4   ? 45.66389 31.53269  98.30156  1.000 106.30764 ? 87  GLY   B CA  1 
ATOM   4083 C  C   . GLY   B 2 4   ? 46.38005 30.94079  97.10327  1.000 118.27918 ? 87  GLY   B C   1 
ATOM   4084 O  O   . GLY   B 2 4   ? 47.23743 31.58606  96.50025  1.000 124.64115 ? 87  GLY   B O   1 
ATOM   4085 N  N   . ASN   B 2 5   ? 46.02374 29.70394  96.75443  1.000 110.74133 ? 88  ASN   B N   1 
ATOM   4086 C  CA  . ASN   B 2 5   ? 46.63411 28.98878  95.63560  1.000 101.08445 ? 88  ASN   B CA  1 
ATOM   4087 C  C   . ASN   B 2 5   ? 45.53872 28.35011  94.77810  1.000 97.95418  ? 88  ASN   B C   1 
ATOM   4088 O  O   . ASN   B 2 5   ? 45.50043 27.13921  94.56299  1.000 101.65495 ? 88  ASN   B O   1 
ATOM   4089 C  CB  . ASN   B 2 5   ? 47.63218 27.94591  96.13641  1.000 107.34600 ? 88  ASN   B CB  1 
ATOM   4090 C  CG  . ASN   B 2 5   ? 47.03998 27.03126  97.19053  1.000 103.01019 ? 88  ASN   B CG  1 
ATOM   4091 O  OD1 . ASN   B 2 5   ? 46.04382 27.36674  97.83111  1.000 95.91569  ? 88  ASN   B OD1 1 
ATOM   4092 N  ND2 . ASN   B 2 5   ? 47.65489 25.86963  97.37917  1.000 100.72851 ? 88  ASN   B ND2 1 
ATOM   4093 N  N   . THR   B 2 6   ? 44.63183 29.18899  94.28293  1.000 94.11592  ? 89  THR   B N   1 
ATOM   4094 C  CA  . THR   B 2 6   ? 43.53134 28.76970  93.42153  1.000 87.85263  ? 89  THR   B CA  1 
ATOM   4095 C  C   . THR   B 2 6   ? 43.45216 29.65913  92.18960  1.000 87.00982  ? 89  THR   B C   1 
ATOM   4096 O  O   . THR   B 2 6   ? 42.36659 30.03948  91.74204  1.000 84.42053  ? 89  THR   B O   1 
ATOM   4097 C  CB  . THR   B 2 6   ? 42.20288 28.78548  94.17584  1.000 84.05848  ? 89  THR   B CB  1 
ATOM   4098 O  OG1 . THR   B 2 6   ? 41.97723 30.09100  94.72311  1.000 78.58822  ? 89  THR   B OG1 1 
ATOM   4099 C  CG2 . THR   B 2 6   ? 42.20915 27.76022  95.30248  1.000 89.29075  ? 89  THR   B CG2 1 
ATOM   4100 N  N   . CYS   B 2 7   ? 44.61003 29.99817  91.61773  1.000 92.75739  ? 90  CYS   B N   1 
ATOM   4101 C  CA  . CYS   B 2 7   ? 44.64207 30.94900  90.51010  1.000 90.66290  ? 90  CYS   B CA  1 
ATOM   4102 C  C   . CYS   B 2 7   ? 43.99456 30.37585  89.25408  1.000 85.16288  ? 90  CYS   B C   1 
ATOM   4103 O  O   . CYS   B 2 7   ? 43.34402 31.10855  88.49749  1.000 76.49545  ? 90  CYS   B O   1 
ATOM   4104 C  CB  . CYS   B 2 7   ? 46.08434 31.37174  90.22897  1.000 95.08092  ? 90  CYS   B CB  1 
ATOM   4105 S  SG  . CYS   B 2 7   ? 47.24456 29.99607  90.03410  1.000 86.54971  ? 90  CYS   B SG  1 
ATOM   4106 N  N   . TYR   B 2 8   ? 44.15327 29.06948  89.01847  1.000 85.83068  ? 91  TYR   B N   1 
ATOM   4107 C  CA  . TYR   B 2 8   ? 43.63036 28.47030  87.79367  1.000 88.98124  ? 91  TYR   B CA  1 
ATOM   4108 C  C   . TYR   B 2 8   ? 42.11077 28.55846  87.72688  1.000 83.81421  ? 91  TYR   B C   1 
ATOM   4109 O  O   . TYR   B 2 8   ? 41.54226 28.64709  86.63241  1.000 86.08822  ? 91  TYR   B O   1 
ATOM   4110 C  CB  . TYR   B 2 8   ? 44.09311 27.01534  87.67800  1.000 90.25114  ? 91  TYR   B CB  1 
ATOM   4111 C  CG  . TYR   B 2 8   ? 43.59943 26.10903  88.78272  1.000 92.98460  ? 91  TYR   B CG  1 
ATOM   4112 C  CD1 . TYR   B 2 8   ? 44.29222 25.99965  89.98207  1.000 94.51903  ? 91  TYR   B CD1 1 
ATOM   4113 C  CD2 . TYR   B 2 8   ? 42.44619 25.35302  88.62097  1.000 88.64044  ? 91  TYR   B CD2 1 
ATOM   4114 C  CE1 . TYR   B 2 8   ? 43.84414 25.16965  90.99194  1.000 94.90388  ? 91  TYR   B CE1 1 
ATOM   4115 C  CE2 . TYR   B 2 8   ? 41.99070 24.52113  89.62415  1.000 84.28768  ? 91  TYR   B CE2 1 
ATOM   4116 C  CZ  . TYR   B 2 8   ? 42.69317 24.43282  90.80711  1.000 90.10629  ? 91  TYR   B CZ  1 
ATOM   4117 O  OH  . TYR   B 2 8   ? 42.24270 23.60427  91.80921  1.000 89.80076  ? 91  TYR   B OH  1 
ATOM   4118 N  N   . LEU   B 2 9   ? 41.44069 28.53927  88.87911  1.000 75.03431  ? 92  LEU   B N   1 
ATOM   4119 C  CA  . LEU   B 2 9   ? 39.99795 28.73237  88.95175  1.000 66.88362  ? 92  LEU   B CA  1 
ATOM   4120 C  C   . LEU   B 2 9   ? 39.61877 30.20700  88.99838  1.000 69.05197  ? 92  LEU   B C   1 
ATOM   4121 O  O   . LEU   B 2 9   ? 38.65083 30.61694  88.34814  1.000 67.52175  ? 92  LEU   B O   1 
ATOM   4122 C  CB  . LEU   B 2 9   ? 39.43068 28.01495  90.18181  1.000 68.02684  ? 92  LEU   B CB  1 
ATOM   4123 C  CG  . LEU   B 2 9   ? 37.95724 28.28637  90.51136  1.000 60.46404  ? 92  LEU   B CG  1 
ATOM   4124 C  CD1 . LEU   B 2 9   ? 37.06593 27.85022  89.36298  1.000 58.23429  ? 92  LEU   B CD1 1 
ATOM   4125 C  CD2 . LEU   B 2 9   ? 37.54374 27.60002  91.80803  1.000 77.20685  ? 92  LEU   B CD2 1 
ATOM   4126 N  N   . ASN   B 2 10  ? 40.36660 31.00957  89.76030  1.000 73.97492  ? 93  ASN   B N   1 
ATOM   4127 C  CA  . ASN   B 2 10  ? 40.01591 32.41563  89.92821  1.000 72.37657  ? 93  ASN   B CA  1 
ATOM   4128 C  C   . ASN   B 2 10  ? 40.11646 33.17452  88.61260  1.000 79.38940  ? 93  ASN   B C   1 
ATOM   4129 O  O   . ASN   B 2 10  ? 39.31974 34.08253  88.35448  1.000 80.89182  ? 93  ASN   B O   1 
ATOM   4130 C  CB  . ASN   B 2 10  ? 40.91040 33.05749  90.98862  1.000 71.37560  ? 93  ASN   B CB  1 
ATOM   4131 C  CG  . ASN   B 2 10  ? 40.66930 32.49282  92.37233  1.000 76.84841  ? 93  ASN   B CG  1 
ATOM   4132 O  OD1 . ASN   B 2 10  ? 40.01531 31.46204  92.53006  1.000 82.96764  ? 93  ASN   B OD1 1 
ATOM   4133 N  ND2 . ASN   B 2 10  ? 41.20160 33.16496  93.38538  1.000 83.90457  ? 93  ASN   B ND2 1 
ATOM   4134 N  N   . SER   B 2 11  ? 41.08353 32.81500  87.76377  1.000 77.69171  ? 94  SER   B N   1 
ATOM   4135 C  CA  . SER   B 2 11  ? 41.22513 33.49509  86.47869  1.000 72.39530  ? 94  SER   B CA  1 
ATOM   4136 C  C   . SER   B 2 11  ? 39.97998 33.30879  85.61929  1.000 71.94492  ? 94  SER   B C   1 
ATOM   4137 O  O   . SER   B 2 11  ? 39.40132 34.28194  85.11707  1.000 70.18332  ? 94  SER   B O   1 
ATOM   4138 C  CB  . SER   B 2 11  ? 42.46633 32.98334  85.74707  1.000 72.54178  ? 94  SER   B CB  1 
ATOM   4139 O  OG  . SER   B 2 11  ? 43.64141 33.25744  86.48870  1.000 75.55170  ? 94  SER   B OG  1 
ATOM   4140 N  N   . ILE   B 2 12  ? 39.54126 32.05995  85.44871  1.000 67.24520  ? 95  ILE   B N   1 
ATOM   4141 C  CA  . ILE   B 2 12  ? 38.37118 31.82029  84.61280  1.000 70.52529  ? 95  ILE   B CA  1 
ATOM   4142 C  C   . ILE   B 2 12  ? 37.10226 32.31524  85.29545  1.000 70.15558  ? 95  ILE   B C   1 
ATOM   4143 O  O   . ILE   B 2 12  ? 36.13068 32.66513  84.61793  1.000 70.03176  ? 95  ILE   B O   1 
ATOM   4144 C  CB  . ILE   B 2 12  ? 38.27691 30.33309  84.22185  1.000 59.56316  ? 95  ILE   B CB  1 
ATOM   4145 C  CG1 . ILE   B 2 12  ? 38.06167 29.45066  85.45117  1.000 68.97047  ? 95  ILE   B CG1 1 
ATOM   4146 C  CG2 . ILE   B 2 12  ? 39.52853 29.90639  83.46947  1.000 64.48195  ? 95  ILE   B CG2 1 
ATOM   4147 C  CD1 . ILE   B 2 12  ? 36.64187 28.94155  85.58421  1.000 69.28138  ? 95  ILE   B CD1 1 
ATOM   4148 N  N   . LEU   B 2 13  ? 37.08682 32.38653  86.63040  1.000 65.41867  ? 96  LEU   B N   1 
ATOM   4149 C  CA  . LEU   B 2 13  ? 35.94467 32.99099  87.31312  1.000 60.32183  ? 96  LEU   B CA  1 
ATOM   4150 C  C   . LEU   B 2 13  ? 35.84844 34.48261  87.00745  1.000 64.70451  ? 96  LEU   B C   1 
ATOM   4151 O  O   . LEU   B 2 13  ? 34.76491 34.99859  86.70218  1.000 65.50209  ? 96  LEU   B O   1 
ATOM   4152 C  CB  . LEU   B 2 13  ? 36.04268 32.75679  88.82059  1.000 59.47598  ? 96  LEU   B CB  1 
ATOM   4153 C  CG  . LEU   B 2 13  ? 35.71758 31.34804  89.31894  1.000 63.68664  ? 96  LEU   B CG  1 
ATOM   4154 C  CD1 . LEU   B 2 13  ? 35.81638 31.27853  90.83395  1.000 70.36111  ? 96  LEU   B CD1 1 
ATOM   4155 C  CD2 . LEU   B 2 13  ? 34.33854 30.91619  88.84763  1.000 64.54212  ? 96  LEU   B CD2 1 
ATOM   4156 N  N   . GLN   B 2 14  ? 36.97628 35.19334  87.09159  1.000 65.63660  ? 97  GLN   B N   1 
ATOM   4157 C  CA  . GLN   B 2 14  ? 36.99755 36.60641  86.72814  1.000 69.16303  ? 97  GLN   B CA  1 
ATOM   4158 C  C   . GLN   B 2 14  ? 36.63434 36.81025  85.26395  1.000 71.56897  ? 97  GLN   B C   1 
ATOM   4159 O  O   . GLN   B 2 14  ? 36.00969 37.81828  84.91297  1.000 69.46559  ? 97  GLN   B O   1 
ATOM   4160 C  CB  . GLN   B 2 14  ? 38.37531 37.20145  87.02021  1.000 71.06732  ? 97  GLN   B CB  1 
ATOM   4161 C  CG  . GLN   B 2 14  ? 38.76387 37.17346  88.48689  1.000 72.01393  ? 97  GLN   B CG  1 
ATOM   4162 C  CD  . GLN   B 2 14  ? 40.24401 36.92432  88.69205  1.000 77.76437  ? 97  GLN   B CD  1 
ATOM   4163 O  OE1 . GLN   B 2 14  ? 40.97097 36.62682  87.74455  1.000 80.69731  ? 97  GLN   B OE1 1 
ATOM   4164 N  NE2 . GLN   B 2 14  ? 40.69706 37.03498  89.93538  1.000 78.50514  ? 97  GLN   B NE2 1 
ATOM   4165 N  N   . VAL   B 2 15  ? 37.02042 35.87213  84.39731  1.000 73.19930  ? 98  VAL   B N   1 
ATOM   4166 C  CA  . VAL   B 2 15  ? 36.63675 35.96271  82.99026  1.000 69.69163  ? 98  VAL   B CA  1 
ATOM   4167 C  C   . VAL   B 2 15  ? 35.12812 35.79620  82.83529  1.000 66.11789  ? 98  VAL   B C   1 
ATOM   4168 O  O   . VAL   B 2 15  ? 34.47067 36.56853  82.12739  1.000 61.92479  ? 98  VAL   B O   1 
ATOM   4169 C  CB  . VAL   B 2 15  ? 37.40868 34.92639  82.15473  1.000 66.73733  ? 98  VAL   B CB  1 
ATOM   4170 C  CG1 . VAL   B 2 15  ? 36.82478 34.83409  80.75388  1.000 64.27214  ? 98  VAL   B CG1 1 
ATOM   4171 C  CG2 . VAL   B 2 15  ? 38.87953 35.29490  82.09285  1.000 74.87088  ? 98  VAL   B CG2 1 
ATOM   4172 N  N   . LEU   B 2 16  ? 34.55778 34.78584  83.49806  1.000 64.36213  ? 99  LEU   B N   1 
ATOM   4173 C  CA  . LEU   B 2 16  ? 33.12175 34.54241  83.40621  1.000 64.22316  ? 99  LEU   B CA  1 
ATOM   4174 C  C   . LEU   B 2 16  ? 32.31363 35.69077  83.99351  1.000 65.40822  ? 99  LEU   B C   1 
ATOM   4175 O  O   . LEU   B 2 16  ? 31.16686 35.91135  83.58631  1.000 63.55304  ? 99  LEU   B O   1 
ATOM   4176 C  CB  . LEU   B 2 16  ? 32.76443 33.23432  84.11354  1.000 53.52672  ? 99  LEU   B CB  1 
ATOM   4177 C  CG  . LEU   B 2 16  ? 33.18332 31.93249  83.43012  1.000 54.56345  ? 99  LEU   B CG  1 
ATOM   4178 C  CD1 . LEU   B 2 16  ? 33.00312 30.75137  84.37063  1.000 49.61990  ? 99  LEU   B CD1 1 
ATOM   4179 C  CD2 . LEU   B 2 16  ? 32.38658 31.72599  82.15318  1.000 61.55528  ? 99  LEU   B CD2 1 
ATOM   4180 N  N   . TYR   B 2 17  ? 32.88335 36.42110  84.95630  1.000 61.38618  ? 100 TYR   B N   1 
ATOM   4181 C  CA  . TYR   B 2 17  ? 32.15589 37.53783  85.55366  1.000 61.78305  ? 100 TYR   B CA  1 
ATOM   4182 C  C   . TYR   B 2 17  ? 31.77360 38.57780  84.50640  1.000 65.81637  ? 100 TYR   B C   1 
ATOM   4183 O  O   . TYR   B 2 17  ? 30.66272 39.12047  84.53705  1.000 68.68225  ? 100 TYR   B O   1 
ATOM   4184 C  CB  . TYR   B 2 17  ? 32.98508 38.18107  86.66490  1.000 65.60265  ? 100 TYR   B CB  1 
ATOM   4185 C  CG  . TYR   B 2 17  ? 32.27101 39.31818  87.36248  1.000 66.22415  ? 100 TYR   B CG  1 
ATOM   4186 C  CD1 . TYR   B 2 17  ? 31.37506 39.07067  88.39398  1.000 65.20359  ? 100 TYR   B CD1 1 
ATOM   4187 C  CD2 . TYR   B 2 17  ? 32.48644 40.63771  86.98468  1.000 67.54141  ? 100 TYR   B CD2 1 
ATOM   4188 C  CE1 . TYR   B 2 17  ? 30.71660 40.10387  89.03172  1.000 63.64703  ? 100 TYR   B CE1 1 
ATOM   4189 C  CE2 . TYR   B 2 17  ? 31.83403 41.67776  87.61751  1.000 74.14202  ? 100 TYR   B CE2 1 
ATOM   4190 C  CZ  . TYR   B 2 17  ? 30.95060 41.40558  88.64036  1.000 74.08983  ? 100 TYR   B CZ  1 
ATOM   4191 O  OH  . TYR   B 2 17  ? 30.29831 42.43920  89.27277  1.000 80.33642  ? 100 TYR   B OH  1 
ATOM   4192 N  N   . PHE   B 2 18  ? 32.67701 38.86935  83.57122  1.000 68.79338  ? 101 PHE   B N   1 
ATOM   4193 C  CA  . PHE   B 2 18  ? 32.41757 39.84248  82.52002  1.000 69.84152  ? 101 PHE   B CA  1 
ATOM   4194 C  C   . PHE   B 2 18  ? 31.85034 39.20902  81.25446  1.000 71.56217  ? 101 PHE   B C   1 
ATOM   4195 O  O   . PHE   B 2 18  ? 31.90547 39.82822  80.18559  1.000 66.95200  ? 101 PHE   B O   1 
ATOM   4196 C  CB  . PHE   B 2 18  ? 33.69320 40.61840  82.18699  1.000 67.66539  ? 101 PHE   B CB  1 
ATOM   4197 C  CG  . PHE   B 2 18  ? 34.16730 41.51423  83.29507  1.000 74.71702  ? 101 PHE   B CG  1 
ATOM   4198 C  CD1 . PHE   B 2 18  ? 33.49639 42.69035  83.58745  1.000 80.71272  ? 101 PHE   B CD1 1 
ATOM   4199 C  CD2 . PHE   B 2 18  ? 35.28975 41.18663  84.03697  1.000 76.89204  ? 101 PHE   B CD2 1 
ATOM   4200 C  CE1 . PHE   B 2 18  ? 33.93124 43.51889  84.60503  1.000 81.76642  ? 101 PHE   B CE1 1 
ATOM   4201 C  CE2 . PHE   B 2 18  ? 35.73080 42.01184  85.05340  1.000 77.27151  ? 101 PHE   B CE2 1 
ATOM   4202 C  CZ  . PHE   B 2 18  ? 35.05015 43.17872  85.33886  1.000 81.21298  ? 101 PHE   B CZ  1 
ATOM   4203 N  N   . CYS   B 2 19  ? 31.31502 37.99384  81.34716  1.000 72.59026  ? 102 CYS   B N   1 
ATOM   4204 C  CA  . CYS   B 2 19  ? 30.71729 37.46771  80.12658  1.000 73.27082  ? 102 CYS   B CA  1 
ATOM   4205 C  C   . CYS   B 2 19  ? 29.27689 37.95369  79.99283  1.000 77.83305  ? 102 CYS   B C   1 
ATOM   4206 O  O   . CYS   B 2 19  ? 28.53865 37.98701  80.98232  1.000 77.00915  ? 102 CYS   B O   1 
ATOM   4207 C  CB  . CYS   B 2 19  ? 30.74605 35.94310  80.11947  1.000 70.76003  ? 102 CYS   B CB  1 
ATOM   4208 S  SG  . CYS   B 2 19  ? 32.39790 35.23842  79.92773  1.000 72.16091  ? 102 CYS   B SG  1 
ATOM   4209 N  N   . PRO   B 2 20  ? 28.86371 38.33725  78.78640  1.000 76.76186  ? 103 PRO   B N   1 
ATOM   4210 C  CA  . PRO   B 2 20  ? 27.50664 38.86715  78.60976  1.000 82.71611  ? 103 PRO   B CA  1 
ATOM   4211 C  C   . PRO   B 2 20  ? 26.45502 37.78911  78.81809  1.000 87.71658  ? 103 PRO   B C   1 
ATOM   4212 O  O   . PRO   B 2 20  ? 26.59817 36.65504  78.35515  1.000 89.59466  ? 103 PRO   B O   1 
ATOM   4213 C  CB  . PRO   B 2 20  ? 27.51093 39.37595  77.16407  1.000 86.45161  ? 103 PRO   B CB  1 
ATOM   4214 C  CG  . PRO   B 2 20  ? 28.56557 38.55662  76.48539  1.000 80.78190  ? 103 PRO   B CG  1 
ATOM   4215 C  CD  . PRO   B 2 20  ? 29.62265 38.31113  77.52390  1.000 74.21322  ? 103 PRO   B CD  1 
ATOM   4216 N  N   . GLY   B 2 21  ? 25.38798 38.15729  79.52846  1.000 90.92932  ? 104 GLY   B N   1 
ATOM   4217 C  CA  . GLY   B 2 21  ? 24.30956 37.24352  79.83119  1.000 84.73215  ? 104 GLY   B CA  1 
ATOM   4218 C  C   . GLY   B 2 21  ? 24.58651 36.26554  80.94982  1.000 72.83545  ? 104 GLY   B C   1 
ATOM   4219 O  O   . GLY   B 2 21  ? 23.63709 35.70590  81.51106  1.000 73.29491  ? 104 GLY   B O   1 
ATOM   4220 N  N   . PHE   B 2 22  ? 25.85578 36.03709  81.29432  1.000 70.55968  ? 105 PHE   B N   1 
ATOM   4221 C  CA  . PHE   B 2 22  ? 26.17589 35.10446  82.36991  1.000 70.93940  ? 105 PHE   B CA  1 
ATOM   4222 C  C   . PHE   B 2 22  ? 25.64768 35.60397  83.70825  1.000 70.80242  ? 105 PHE   B C   1 
ATOM   4223 O  O   . PHE   B 2 22  ? 25.09001 34.82942  84.49231  1.000 71.17913  ? 105 PHE   B O   1 
ATOM   4224 C  CB  . PHE   B 2 22  ? 27.68797 34.87982  82.42620  1.000 64.74007  ? 105 PHE   B CB  1 
ATOM   4225 C  CG  . PHE   B 2 22  ? 28.12262 33.90732  83.48679  1.000 54.10497  ? 105 PHE   B CG  1 
ATOM   4226 C  CD1 . PHE   B 2 22  ? 28.09320 32.54380  83.24943  1.000 53.22118  ? 105 PHE   B CD1 1 
ATOM   4227 C  CD2 . PHE   B 2 22  ? 28.57464 34.35843  84.71707  1.000 58.96691  ? 105 PHE   B CD2 1 
ATOM   4228 C  CE1 . PHE   B 2 22  ? 28.49691 31.64585  84.22151  1.000 54.65553  ? 105 PHE   B CE1 1 
ATOM   4229 C  CE2 . PHE   B 2 22  ? 28.97952 33.46622  85.69356  1.000 59.09809  ? 105 PHE   B CE2 1 
ATOM   4230 C  CZ  . PHE   B 2 22  ? 28.94082 32.10818  85.44522  1.000 61.35830  ? 105 PHE   B CZ  1 
ATOM   4231 N  N   . LYS   B 2 23  ? 25.79636 36.90178  83.97226  1.000 66.94475  ? 106 LYS   B N   1 
ATOM   4232 C  CA  . LYS   B 2 23  ? 25.36786 37.48559  85.24141  1.000 67.85950  ? 106 LYS   B CA  1 
ATOM   4233 C  C   . LYS   B 2 23  ? 23.86296 37.36146  85.43733  1.000 73.30554  ? 106 LYS   B C   1 
ATOM   4234 O  O   . LYS   B 2 23  ? 23.39309 36.71682  86.38432  1.000 68.39458  ? 106 LYS   B O   1 
ATOM   4235 C  CB  . LYS   B 2 23  ? 25.79134 38.95552  85.30243  1.000 79.26254  ? 106 LYS   B CB  1 
ATOM   4236 C  CG  . LYS   B 2 23  ? 27.28186 39.18319  85.16315  1.000 79.44895  ? 106 LYS   B CG  1 
ATOM   4237 C  CD  . LYS   B 2 23  ? 27.89460 39.57204  86.49457  1.000 72.52309  ? 106 LYS   B CD  1 
ATOM   4238 C  CE  . LYS   B 2 23  ? 27.25242 40.83874  87.03398  1.000 71.89070  ? 106 LYS   B CE  1 
ATOM   4239 N  NZ  . LYS   B 2 23  ? 27.77076 41.19604  88.37900  1.000 79.21292  ? 106 LYS   B NZ  1 
ATOM   4240 N  N   . SER   B 2 24  ? 23.09041 38.00245  84.55962  1.000 78.85435  ? 107 SER   B N   1 
ATOM   4241 C  CA  . SER   B 2 24  ? 21.63842 37.92161  84.65775  1.000 76.16075  ? 107 SER   B CA  1 
ATOM   4242 C  C   . SER   B 2 24  ? 21.14657 36.49273  84.47331  1.000 74.71521  ? 107 SER   B C   1 
ATOM   4243 O  O   . SER   B 2 24  ? 20.12703 36.10422  85.05924  1.000 84.93879  ? 107 SER   B O   1 
ATOM   4244 C  CB  . SER   B 2 24  ? 20.98777 38.84597  83.62733  1.000 77.73544  ? 107 SER   B CB  1 
ATOM   4245 O  OG  . SER   B 2 24  ? 19.57756 38.80536  83.73196  1.000 89.49743  ? 107 SER   B OG  1 
ATOM   4246 N  N   . GLY   B 2 25  ? 21.86416 35.69496  83.68040  1.000 69.69730  ? 108 GLY   B N   1 
ATOM   4247 C  CA  . GLY   B 2 25  ? 21.48786 34.30094  83.51649  1.000 70.37190  ? 108 GLY   B CA  1 
ATOM   4248 C  C   . GLY   B 2 25  ? 21.52731 33.53307  84.82292  1.000 75.92586  ? 108 GLY   B C   1 
ATOM   4249 O  O   . GLY   B 2 25  ? 20.54551 32.89599  85.21351  1.000 77.46844  ? 108 GLY   B O   1 
ATOM   4250 N  N   . VAL   B 2 26  ? 22.66209 33.59293  85.52570  1.000 77.27331  ? 109 VAL   B N   1 
ATOM   4251 C  CA  . VAL   B 2 26  ? 22.75820 32.88527  86.79801  1.000 72.67133  ? 109 VAL   B CA  1 
ATOM   4252 C  C   . VAL   B 2 26  ? 21.84920 33.52207  87.84145  1.000 73.77946  ? 109 VAL   B C   1 
ATOM   4253 O  O   . VAL   B 2 26  ? 21.36426 32.83206  88.74402  1.000 70.31597  ? 109 VAL   B O   1 
ATOM   4254 C  CB  . VAL   B 2 26  ? 24.21801 32.81507  87.28813  1.000 62.04453  ? 109 VAL   B CB  1 
ATOM   4255 C  CG1 . VAL   B 2 26  ? 25.09876 32.13846  86.24886  1.000 64.36709  ? 109 VAL   B CG1 1 
ATOM   4256 C  CG2 . VAL   B 2 26  ? 24.74173 34.19516  87.63236  1.000 70.74730  ? 109 VAL   B CG2 1 
ATOM   4257 N  N   . LYS   B 2 27  ? 21.57223 34.82543  87.73020  1.000 71.80429  ? 110 LYS   B N   1 
ATOM   4258 C  CA  . LYS   B 2 27  ? 20.63904 35.45521  88.66155  1.000 70.61992  ? 110 LYS   B CA  1 
ATOM   4259 C  C   . LYS   B 2 27  ? 19.24009 34.86360  88.51750  1.000 74.92766  ? 110 LYS   B C   1 
ATOM   4260 O  O   . LYS   B 2 27  ? 18.64437 34.38509  89.49285  1.000 77.96203  ? 110 LYS   B O   1 
ATOM   4261 C  CB  . LYS   B 2 27  ? 20.60642 36.96869  88.43950  1.000 77.26267  ? 110 LYS   B CB  1 
ATOM   4262 C  CG  . LYS   B 2 27  ? 19.67295 37.70134  89.39501  1.000 76.54868  ? 110 LYS   B CG  1 
ATOM   4263 C  CD  . LYS   B 2 27  ? 19.15001 39.00211  88.80241  1.000 76.05961  ? 110 LYS   B CD  1 
ATOM   4264 C  CE  . LYS   B 2 27  ? 20.26310 40.00987  88.57813  1.000 67.45151  ? 110 LYS   B CE  1 
ATOM   4265 N  NZ  . LYS   B 2 27  ? 19.73213 41.29874  88.05276  1.000 70.93287  ? 110 LYS   B NZ  1 
ATOM   4266 N  N   . HIS   B 2 28  ? 18.69526 34.89583  87.29875  1.000 79.75479  ? 111 HIS   B N   1 
ATOM   4267 C  CA  . HIS   B 2 28  ? 17.36257 34.35531  87.06148  1.000 80.87295  ? 111 HIS   B CA  1 
ATOM   4268 C  C   . HIS   B 2 28  ? 17.32239 32.83416  87.11599  1.000 76.28189  ? 111 HIS   B C   1 
ATOM   4269 O  O   . HIS   B 2 28  ? 16.22614 32.26415  87.14246  1.000 77.29269  ? 111 HIS   B O   1 
ATOM   4270 C  CB  . HIS   B 2 28  ? 16.82140 34.84621  85.71756  1.000 88.92016  ? 111 HIS   B CB  1 
ATOM   4271 C  CG  . HIS   B 2 28  ? 15.96133 36.06728  85.82645  1.000 102.00736 ? 111 HIS   B CG  1 
ATOM   4272 N  ND1 . HIS   B 2 28  ? 16.47928 37.32965  86.02221  1.000 97.93023  ? 111 HIS   B ND1 1 
ATOM   4273 C  CD2 . HIS   B 2 28  ? 14.61614 36.21603  85.77994  1.000 100.16559 ? 111 HIS   B CD2 1 
ATOM   4274 C  CE1 . HIS   B 2 28  ? 15.49078 38.20403  86.08456  1.000 95.87942  ? 111 HIS   B CE1 1 
ATOM   4275 N  NE2 . HIS   B 2 28  ? 14.34992 37.55407  85.94076  1.000 99.89505  ? 111 HIS   B NE2 1 
ATOM   4276 N  N   . LEU   B 2 29  ? 18.47634 32.16626  87.12624  1.000 76.14938  ? 112 LEU   B N   1 
ATOM   4277 C  CA  . LEU   B 2 29  ? 18.50476 30.73240  87.38605  1.000 73.29480  ? 112 LEU   B CA  1 
ATOM   4278 C  C   . LEU   B 2 29  ? 18.49744 30.41925  88.87878  1.000 73.02027  ? 112 LEU   B C   1 
ATOM   4279 O  O   . LEU   B 2 29  ? 17.87728 29.43888  89.30168  1.000 70.82197  ? 112 LEU   B O   1 
ATOM   4280 C  CB  . LEU   B 2 29  ? 19.73245 30.10319  86.72158  1.000 66.00786  ? 112 LEU   B CB  1 
ATOM   4281 C  CG  . LEU   B 2 29  ? 19.62230 28.63250  86.31593  1.000 66.61434  ? 112 LEU   B CG  1 
ATOM   4282 C  CD1 . LEU   B 2 29  ? 18.61695 28.46563  85.18643  1.000 64.19321  ? 112 LEU   B CD1 1 
ATOM   4283 C  CD2 . LEU   B 2 29  ? 20.98326 28.09217  85.91266  1.000 68.88130  ? 112 LEU   B CD2 1 
ATOM   4284 N  N   . PHE   B 2 30  ? 19.17740 31.23585  89.68612  1.000 74.84357  ? 113 PHE   B N   1 
ATOM   4285 C  CA  . PHE   B 2 30  ? 19.17077 31.03906  91.13122  1.000 74.07083  ? 113 PHE   B CA  1 
ATOM   4286 C  C   . PHE   B 2 30  ? 17.85427 31.49127  91.75133  1.000 76.47324  ? 113 PHE   B C   1 
ATOM   4287 O  O   . PHE   B 2 30  ? 17.48530 31.02788  92.84241  1.000 84.13092  ? 113 PHE   B O   1 
ATOM   4288 C  CB  . PHE   B 2 30  ? 20.35475 31.78135  91.75564  1.000 67.64020  ? 113 PHE   B CB  1 
ATOM   4289 C  CG  . PHE   B 2 30  ? 20.19241 32.05932  93.21985  1.000 66.84207  ? 113 PHE   B CG  1 
ATOM   4290 C  CD1 . PHE   B 2 30  ? 20.41705 31.06677  94.15923  1.000 78.07420  ? 113 PHE   B CD1 1 
ATOM   4291 C  CD2 . PHE   B 2 30  ? 19.81697 33.31747  93.65777  1.000 65.17016  ? 113 PHE   B CD2 1 
ATOM   4292 C  CE1 . PHE   B 2 30  ? 20.26416 31.32526  95.50679  1.000 79.58445  ? 113 PHE   B CE1 1 
ATOM   4293 C  CE2 . PHE   B 2 30  ? 19.66359 33.58051  95.00074  1.000 74.78703  ? 113 PHE   B CE2 1 
ATOM   4294 C  CZ  . PHE   B 2 30  ? 19.88751 32.58380  95.92767  1.000 77.13822  ? 113 PHE   B CZ  1 
ATOM   4295 N  N   . ASN   B 2 31  ? 17.15129 32.41037  91.08469  1.000 73.28213  ? 114 ASN   B N   1 
ATOM   4296 C  CA  . ASN   B 2 31  ? 15.81137 32.77947  91.52957  1.000 81.00201  ? 114 ASN   B CA  1 
ATOM   4297 C  C   . ASN   B 2 31  ? 14.91664 31.55227  91.66337  1.000 85.93680  ? 114 ASN   B C   1 
ATOM   4298 O  O   . ASN   B 2 31  ? 14.16674 31.42243  92.63817  1.000 92.55996  ? 114 ASN   B O   1 
ATOM   4299 C  CB  . ASN   B 2 31  ? 15.19373 33.79026  90.56024  1.000 86.95092  ? 114 ASN   B CB  1 
ATOM   4300 C  CG  . ASN   B 2 31  ? 15.74438 35.19173  90.75053  1.000 93.77546  ? 114 ASN   B CG  1 
ATOM   4301 O  OD1 . ASN   B 2 31  ? 16.74371 35.38715  91.44301  1.000 96.78241  ? 114 ASN   B OD1 1 
ATOM   4302 N  ND2 . ASN   B 2 31  ? 15.09340 36.17549  90.13766  1.000 89.44581  ? 114 ASN   B ND2 1 
ATOM   4303 N  N   . ILE   B 2 32  ? 14.99741 30.63188  90.69945  1.000 75.14694  ? 115 ILE   B N   1 
ATOM   4304 C  CA  . ILE   B 2 32  ? 14.17047 29.42863  90.73698  1.000 78.32433  ? 115 ILE   B CA  1 
ATOM   4305 C  C   . ILE   B 2 32  ? 14.54795 28.55058  91.92468  1.000 82.42296  ? 115 ILE   B C   1 
ATOM   4306 O  O   . ILE   B 2 32  ? 13.67949 27.96231  92.58186  1.000 86.57296  ? 115 ILE   B O   1 
ATOM   4307 C  CB  . ILE   B 2 32  ? 14.29170 28.66376  89.40654  1.000 79.08545  ? 115 ILE   B CB  1 
ATOM   4308 C  CG1 . ILE   B 2 32  ? 13.99712 29.59779  88.23326  1.000 77.31249  ? 115 ILE   B CG1 1 
ATOM   4309 C  CG2 . ILE   B 2 32  ? 13.35836 27.46252  89.39002  1.000 83.02668  ? 115 ILE   B CG2 1 
ATOM   4310 C  CD1 . ILE   B 2 32  ? 14.19411 28.95819  86.88035  1.000 81.11754  ? 115 ILE   B CD1 1 
ATOM   4311 N  N   . ILE   B 2 33  ? 15.84517 28.44552  92.21910  1.000 80.31663  ? 116 ILE   B N   1 
ATOM   4312 C  CA  . ILE   B 2 33  ? 16.28589 27.61945  93.33844  1.000 78.48640  ? 116 ILE   B CA  1 
ATOM   4313 C  C   . ILE   B 2 33  ? 15.79792 28.20305  94.65788  1.000 82.50768  ? 116 ILE   B C   1 
ATOM   4314 O  O   . ILE   B 2 33  ? 15.36063 27.46979  95.55356  1.000 84.77418  ? 116 ILE   B O   1 
ATOM   4315 C  CB  . ILE   B 2 33  ? 17.81683 27.46557  93.31443  1.000 75.63577  ? 116 ILE   B CB  1 
ATOM   4316 C  CG1 . ILE   B 2 33  ? 18.26545 26.86872  91.97979  1.000 75.21367  ? 116 ILE   B CG1 1 
ATOM   4317 C  CG2 . ILE   B 2 33  ? 18.28688 26.59985  94.47363  1.000 79.84755  ? 116 ILE   B CG2 1 
ATOM   4318 C  CD1 . ILE   B 2 33  ? 19.75278 26.63494  91.88639  1.000 72.29217  ? 116 ILE   B CD1 1 
ATOM   4319 N  N   . SER   B 2 34  ? 15.85903 29.52891  94.79908  1.000 81.28494  ? 117 SER   B N   1 
ATOM   4320 C  CA  . SER   B 2 34  ? 15.34270 30.15790  96.01291  1.000 81.58858  ? 117 SER   B CA  1 
ATOM   4321 C  C   . SER   B 2 34  ? 13.83352 29.96611  96.13220  1.000 88.25330  ? 117 SER   B C   1 
ATOM   4322 O  O   . SER   B 2 34  ? 13.31518 29.69656  97.22779  1.000 97.22071  ? 117 SER   B O   1 
ATOM   4323 C  CB  . SER   B 2 34  ? 15.70148 31.64356  96.02986  1.000 77.06169  ? 117 SER   B CB  1 
ATOM   4324 O  OG  . SER   B 2 34  ? 15.16110 32.31376  94.90470  1.000 85.56046  ? 117 SER   B OG  1 
ATOM   4325 N  N   . ARG   B 2 35  ? 13.11420 30.10432  95.01290  1.000 82.90583  ? 118 ARG   B N   1 
ATOM   4326 C  CA  . ARG   B 2 35  ? 11.67666 29.85563  95.01386  1.000 89.88150  ? 118 ARG   B CA  1 
ATOM   4327 C  C   . ARG   B 2 35  ? 11.36616 28.43845  95.47019  1.000 94.56322  ? 118 ARG   B C   1 
ATOM   4328 O  O   . ARG   B 2 35  ? 10.44505 28.22528  96.26295  1.000 99.20069  ? 118 ARG   B O   1 
ATOM   4329 C  CB  . ARG   B 2 35  ? 11.09397 30.09836  93.62099  1.000 89.75643  ? 118 ARG   B CB  1 
ATOM   4330 C  CG  . ARG   B 2 35  ? 11.14423 31.53860  93.14753  1.000 96.53145  ? 118 ARG   B CG  1 
ATOM   4331 C  CD  . ARG   B 2 35  ? 10.84933 31.61884  91.65758  1.000 98.29339  ? 118 ARG   B CD  1 
ATOM   4332 N  NE  . ARG   B 2 35  ? 11.25558 32.89460  91.08052  1.000 104.60923 ? 118 ARG   B NE  1 
ATOM   4333 C  CZ  . ARG   B 2 35  ? 11.24570 33.16538  89.78233  1.000 98.73261  ? 118 ARG   B CZ  1 
ATOM   4334 N  NH1 . ARG   B 2 35  ? 10.85090 32.26945  88.89231  1.000 101.45763 ? 118 ARG   B NH1 1 
ATOM   4335 N  NH2 . ARG   B 2 35  ? 11.64512 34.36391  89.36622  1.000 89.78434  ? 118 ARG   B NH2 1 
ATOM   4336 N  N   . LYS   B 2 36  ? 12.12647 27.45567  94.98151  1.000 93.92038  ? 119 LYS   B N   1 
ATOM   4337 C  CA  . LYS   B 2 36  ? 11.87380 26.07026  95.36695  1.000 95.35480  ? 119 LYS   B CA  1 
ATOM   4338 C  C   . LYS   B 2 36  ? 12.21156 25.83059  96.83311  1.000 99.67199  ? 119 LYS   B C   1 
ATOM   4339 O  O   . LYS   B 2 36  ? 11.49339 25.09977  97.52722  1.000 100.78981 ? 119 LYS   B O   1 
ATOM   4340 C  CB  . LYS   B 2 36  ? 12.66066 25.11789  94.46806  1.000 88.47804  ? 119 LYS   B CB  1 
ATOM   4341 C  CG  . LYS   B 2 36  ? 12.13455 25.04697  93.04521  1.000 88.87974  ? 119 LYS   B CG  1 
ATOM   4342 C  CD  . LYS   B 2 36  ? 12.70750 23.85519  92.29951  1.000 86.76061  ? 119 LYS   B CD  1 
ATOM   4343 C  CE  . LYS   B 2 36  ? 12.07270 23.71234  90.92629  1.000 91.63793  ? 119 LYS   B CE  1 
ATOM   4344 N  NZ  . LYS   B 2 36  ? 12.54199 22.48715  90.22325  1.000 97.10073  ? 119 LYS   B NZ  1 
ATOM   4345 N  N   . LYS   B 2 37  ? 13.29853 26.43516  97.32179  1.000 100.89232 ? 120 LYS   B N   1 
ATOM   4346 C  CA  . LYS   B 2 37  ? 13.62371 26.33711  98.74190  1.000 99.93401  ? 120 LYS   B CA  1 
ATOM   4347 C  C   . LYS   B 2 37  ? 12.46483 26.82766  99.59940  1.000 108.06227 ? 120 LYS   B C   1 
ATOM   4348 O  O   . LYS   B 2 37  ? 12.00584 26.12591  100.50869 1.000 108.69474 ? 120 LYS   B O   1 
ATOM   4349 C  CB  . LYS   B 2 37  ? 14.89176 27.13340  99.05801  1.000 95.63253  ? 120 LYS   B CB  1 
ATOM   4350 C  CG  . LYS   B 2 37  ? 16.18625 26.48904  98.59102  1.000 94.04129  ? 120 LYS   B CG  1 
ATOM   4351 C  CD  . LYS   B 2 37  ? 17.33308 26.83157  99.53457  1.000 97.59854  ? 120 LYS   B CD  1 
ATOM   4352 C  CE  . LYS   B 2 37  ? 18.52728 27.40548  98.78941  1.000 96.06514  ? 120 LYS   B CE  1 
ATOM   4353 N  NZ  . LYS   B 2 37  ? 18.23175 28.74618  98.21271  1.000 97.13406  ? 120 LYS   B NZ  1 
ATOM   4354 N  N   . GLU   B 2 38  ? 11.95902 28.02786  99.30725  1.000 110.90716 ? 121 GLU   B N   1 
ATOM   4355 C  CA  . GLU   B 2 38  ? 10.88457 28.57224  100.13410 1.000 114.10152 ? 121 GLU   B CA  1 
ATOM   4356 C  C   . GLU   B 2 38  ? 9.56519  27.83256  99.92144  1.000 117.92094 ? 121 GLU   B C   1 
ATOM   4357 O  O   . GLU   B 2 38  ? 8.76122  27.72203  100.85659 1.000 120.45475 ? 121 GLU   B O   1 
ATOM   4358 C  CB  . GLU   B 2 38  ? 10.72748 30.06830  99.86802  1.000 105.90783 ? 121 GLU   B CB  1 
ATOM   4359 C  CG  . GLU   B 2 38  ? 11.89533 30.88822  100.39875 1.000 111.69627 ? 121 GLU   B CG  1 
ATOM   4360 C  CD  . GLU   B 2 38  ? 11.74244 32.37289  100.14406 1.000 126.24106 ? 121 GLU   B CD  1 
ATOM   4361 O  OE1 . GLU   B 2 38  ? 10.86183 32.75490  99.34566  1.000 120.51702 ? 121 GLU   B OE1 1 
ATOM   4362 O  OE2 . GLU   B 2 38  ? 12.50560 33.15864  100.74515 1.000 137.56757 ? 121 GLU   B OE2 1 
ATOM   4363 N  N   . ALA   B 2 39  ? 9.33265  27.29840  98.71928  1.000 117.91168 ? 122 ALA   B N   1 
ATOM   4364 C  CA  . ALA   B 2 39  ? 8.10955  26.54422  98.46727  1.000 121.52004 ? 122 ALA   B CA  1 
ATOM   4365 C  C   . ALA   B 2 39  ? 8.10068  25.23316  99.24075  1.000 123.51675 ? 122 ALA   B C   1 
ATOM   4366 O  O   . ALA   B 2 39  ? 7.05874  24.82426  99.76644  1.000 130.52863 ? 122 ALA   B O   1 
ATOM   4367 C  CB  . ALA   B 2 39  ? 7.94960  26.28718  96.96903  1.000 115.26330 ? 122 ALA   B CB  1 
ATOM   4368 N  N   . LEU   B 2 40  ? 9.24828  24.55466  99.31708  1.000 118.50390 ? 123 LEU   B N   1 
ATOM   4369 C  CA  . LEU   B 2 40  ? 9.34016  23.37623  100.16979 1.000 118.96701 ? 123 LEU   B CA  1 
ATOM   4370 C  C   . LEU   B 2 40  ? 9.35151  23.74385  101.64706 1.000 123.99571 ? 123 LEU   B C   1 
ATOM   4371 O  O   . LEU   B 2 40  ? 8.96937  22.91632  102.48145 1.000 128.91486 ? 123 LEU   B O   1 
ATOM   4372 C  CB  . LEU   B 2 40  ? 10.58085 22.55308  99.81874  1.000 109.61016 ? 123 LEU   B CB  1 
ATOM   4373 C  CG  . LEU   B 2 40  ? 10.39181 21.48670  98.73511  1.000 107.38277 ? 123 LEU   B CG  1 
ATOM   4374 C  CD1 . LEU   B 2 40  ? 9.19701  20.59762  99.05926  1.000 105.46403 ? 123 LEU   B CD1 1 
ATOM   4375 C  CD2 . LEU   B 2 40  ? 10.24310 22.10917  97.35392  1.000 110.79448 ? 123 LEU   B CD2 1 
ATOM   4376 N  N   . LYS   B 2 41  ? 9.78461  24.96105  101.98811 1.000 122.97665 ? 124 LYS   B N   1 
ATOM   4377 C  CA  . LYS   B 2 41  ? 9.61292  25.44181  103.35486 1.000 124.74803 ? 124 LYS   B CA  1 
ATOM   4378 C  C   . LYS   B 2 41  ? 8.14070  25.60091  103.70952 1.000 128.49949 ? 124 LYS   B C   1 
ATOM   4379 O  O   . LYS   B 2 41  ? 7.75243  25.36146  104.85849 1.000 131.44394 ? 124 LYS   B O   1 
ATOM   4380 C  CB  . LYS   B 2 41  ? 10.34520 26.76931  103.55199 1.000 114.53117 ? 124 LYS   B CB  1 
ATOM   4381 C  CG  . LYS   B 2 41  ? 11.85119 26.64252  103.68943 1.000 108.27706 ? 124 LYS   B CG  1 
ATOM   4382 C  CD  . LYS   B 2 41  ? 12.47817 27.98164  104.04068 1.000 100.69565 ? 124 LYS   B CD  1 
ATOM   4383 C  CE  . LYS   B 2 41  ? 13.97410 27.85076  104.27173 1.000 103.96223 ? 124 LYS   B CE  1 
ATOM   4384 N  NZ  . LYS   B 2 41  ? 14.58203 29.14129  104.69996 1.000 106.95704 ? 124 LYS   B NZ  1 
ATOM   4385 N  N   . ASP   B 2 42  ? 7.31069  26.00785  102.74688 1.000 127.16526 ? 125 ASP   B N   1 
ATOM   4386 C  CA  . ASP   B 2 42  ? 5.88092  26.12204  103.01780 1.000 131.07628 ? 125 ASP   B CA  1 
ATOM   4387 C  C   . ASP   B 2 42  ? 5.17753  24.77390  102.89232 1.000 134.52783 ? 125 ASP   B C   1 
ATOM   4388 O  O   . ASP   B 2 42  ? 4.33382  24.43278  103.72886 1.000 138.93578 ? 125 ASP   B O   1 
ATOM   4389 C  CB  . ASP   B 2 42  ? 5.24314  27.14821  102.07915 1.000 133.41356 ? 125 ASP   B CB  1 
ATOM   4390 C  CG  . ASP   B 2 42  ? 3.94493  27.71878  102.62977 1.000 136.84119 ? 125 ASP   B CG  1 
ATOM   4391 O  OD1 . ASP   B 2 42  ? 3.28856  27.04256  103.44999 1.000 141.19725 ? 125 ASP   B OD1 1 
ATOM   4392 O  OD2 . ASP   B 2 42  ? 3.58029  28.84904  102.24254 1.000 129.91210 ? 125 ASP   B OD2 1 
ATOM   4393 N  N   . GLU   B 2 43  ? 5.50955  23.99690  101.86526 1.000 131.51830 ? 126 GLU   B N   1 
ATOM   4394 C  CA  . GLU   B 2 43  ? 4.88888  22.69058  101.66143 1.000 122.09500 ? 126 GLU   B CA  1 
ATOM   4395 C  C   . GLU   B 2 43  ? 5.44790  21.66919  102.64769 1.000 119.55923 ? 126 GLU   B C   1 
ATOM   4396 O  O   . GLU   B 2 43  ? 4.70137  20.88785  103.23804 1.000 118.14737 ? 126 GLU   B O   1 
ATOM   4397 C  CB  . GLU   B 2 43  ? 5.09876  22.21292  100.21966 1.000 116.63930 ? 126 GLU   B CB  1 
ATOM   4398 C  CG  . GLU   B 2 43  ? 4.21425  21.04170  99.79988  1.000 117.75673 ? 126 GLU   B CG  1 
ATOM   4399 C  CD  . GLU   B 2 43  ? 4.75894  19.69511  100.24021 1.000 123.80304 ? 126 GLU   B CD  1 
ATOM   4400 O  OE1 . GLU   B 2 43  ? 5.99050  19.57553  100.41191 1.000 117.35384 ? 126 GLU   B OE1 1 
ATOM   4401 O  OE2 . GLU   B 2 43  ? 3.95370  18.75691  100.41768 1.000 128.72740 ? 126 GLU   B OE2 1 
ATOM   4402 N  N   . ASN   B 2 51  ? 11.24217 16.02980  97.83099  1.000 102.15560 ? 134 ASN   B N   1 
ATOM   4403 C  CA  . ASN   B 2 51  ? 12.25589 15.02185  98.11820  1.000 120.53979 ? 134 ASN   B CA  1 
ATOM   4404 C  C   . ASN   B 2 51  ? 13.06744 14.70686  96.86494  1.000 129.11776 ? 134 ASN   B C   1 
ATOM   4405 O  O   . ASN   B 2 51  ? 12.72707 13.79910  96.10629  1.000 128.10462 ? 134 ASN   B O   1 
ATOM   4406 C  CB  . ASN   B 2 51  ? 11.60611 13.74871  98.66517  1.000 123.00980 ? 134 ASN   B CB  1 
ATOM   4407 C  CG  . ASN   B 2 51  ? 12.61350 12.79748  99.28000  1.000 123.60563 ? 134 ASN   B CG  1 
ATOM   4408 O  OD1 . ASN   B 2 51  ? 13.68288 13.21221  99.72746  1.000 115.86571 ? 134 ASN   B OD1 1 
ATOM   4409 N  ND2 . ASN   B 2 51  ? 12.27559 11.51341  99.30718  1.000 125.67663 ? 134 ASN   B ND2 1 
ATOM   4410 N  N   . CYS   B 2 52  ? 14.14049 15.46118  96.65366  1.000 124.83897 ? 135 CYS   B N   1 
ATOM   4411 C  CA  . CYS   B 2 52  ? 14.97290 15.32653  95.46844  1.000 120.14310 ? 135 CYS   B CA  1 
ATOM   4412 C  C   . CYS   B 2 52  ? 16.23975 14.53755  95.78678  1.000 112.23288 ? 135 CYS   B C   1 
ATOM   4413 O  O   . CYS   B 2 52  ? 16.58211 14.29313  96.94565  1.000 104.17027 ? 135 CYS   B O   1 
ATOM   4414 C  CB  . CYS   B 2 52  ? 15.32582 16.70649  94.90399  1.000 112.30050 ? 135 CYS   B CB  1 
ATOM   4415 S  SG  . CYS   B 2 52  ? 16.21113 16.67144  93.32809  1.000 94.88205  ? 135 CYS   B SG  1 
ATOM   4416 N  N   . LYS   B 2 53  ? 16.94000 14.13969  94.72892  1.000 114.30088 ? 136 LYS   B N   1 
ATOM   4417 C  CA  . LYS   B 2 53  ? 18.15473 13.35213  94.87226  1.000 108.70794 ? 136 LYS   B CA  1 
ATOM   4418 C  C   . LYS   B 2 53  ? 19.31773 14.23212  95.32005  1.000 101.20448 ? 136 LYS   B C   1 
ATOM   4419 O  O   . LYS   B 2 53  ? 19.40658 15.41218  94.96741  1.000 101.46889 ? 136 LYS   B O   1 
ATOM   4420 C  CB  . LYS   B 2 53  ? 18.49615 12.65555  93.55311  1.000 100.71811 ? 136 LYS   B CB  1 
ATOM   4421 C  CG  . LYS   B 2 53  ? 19.65298 11.67118  93.63582  1.000 90.85602  ? 136 LYS   B CG  1 
ATOM   4422 C  CD  . LYS   B 2 53  ? 19.88497 10.98285  92.30114  1.000 85.71578  ? 136 LYS   B CD  1 
ATOM   4423 C  CE  . LYS   B 2 53  ? 21.06046 10.02255  92.36981  1.000 83.89267  ? 136 LYS   B CE  1 
ATOM   4424 N  NZ  . LYS   B 2 53  ? 20.86110 8.97108   93.40426  1.000 78.01255  ? 136 LYS   B NZ  1 
ATOM   4425 N  N   . GLU   B 2 54  ? 20.21546 13.64077  96.11383  1.000 102.30403 ? 137 GLU   B N   1 
ATOM   4426 C  CA  . GLU   B 2 54  ? 21.36452 14.38507  96.61965  1.000 110.15695 ? 137 GLU   B CA  1 
ATOM   4427 C  C   . GLU   B 2 54  ? 22.35405 14.71534  95.50820  1.000 107.16659 ? 137 GLU   B C   1 
ATOM   4428 O  O   . GLU   B 2 54  ? 23.00336 15.76905  95.55004  1.000 96.84660  ? 137 GLU   B O   1 
ATOM   4429 C  CB  . GLU   B 2 54  ? 22.04901 13.58853  97.73310  1.000 116.36028 ? 137 GLU   B CB  1 
ATOM   4430 C  CG  . GLU   B 2 54  ? 22.92134 14.41779  98.66821  1.000 127.96746 ? 137 GLU   B CG  1 
ATOM   4431 C  CD  . GLU   B 2 54  ? 24.29918 14.70226  98.10096  1.000 127.84415 ? 137 GLU   B CD  1 
ATOM   4432 O  OE1 . GLU   B 2 54  ? 24.76792 13.92135  97.24604  1.000 129.25354 ? 137 GLU   B OE1 1 
ATOM   4433 O  OE2 . GLU   B 2 54  ? 24.91254 15.71064  98.50979  1.000 114.65749 ? 137 GLU   B OE2 1 
ATOM   4434 N  N   . ASP   B 2 55  ? 22.48512 13.83135  94.51439  1.000 104.80843 ? 138 ASP   B N   1 
ATOM   4435 C  CA  . ASP   B 2 55  ? 23.38937 14.09534  93.39931  1.000 107.63271 ? 138 ASP   B CA  1 
ATOM   4436 C  C   . ASP   B 2 55  ? 22.98224 15.35881  92.65145  1.000 95.14869  ? 138 ASP   B C   1 
ATOM   4437 O  O   . ASP   B 2 55  ? 23.83641 16.16781  92.27033  1.000 86.42709  ? 138 ASP   B O   1 
ATOM   4438 C  CB  . ASP   B 2 55  ? 23.41831 12.89282  92.45473  1.000 113.35802 ? 138 ASP   B CB  1 
ATOM   4439 C  CG  . ASP   B 2 55  ? 24.52206 12.98867  91.41728  1.000 129.34081 ? 138 ASP   B CG  1 
ATOM   4440 O  OD1 . ASP   B 2 55  ? 25.41702 13.84660  91.57066  1.000 127.91791 ? 138 ASP   B OD1 1 
ATOM   4441 O  OD2 . ASP   B 2 55  ? 24.49343 12.20441  90.44542  1.000 127.90735 ? 138 ASP   B OD2 1 
ATOM   4442 N  N   . SER   B 2 56  ? 21.67839 15.54730  92.43663  1.000 90.84633  ? 139 SER   B N   1 
ATOM   4443 C  CA  . SER   B 2 56  ? 21.19933 16.77925  91.82040  1.000 83.61369  ? 139 SER   B CA  1 
ATOM   4444 C  C   . SER   B 2 56  ? 21.24898 17.94580  92.79826  1.000 81.11514  ? 139 SER   B C   1 
ATOM   4445 O  O   . SER   B 2 56  ? 21.40040 19.10008  92.38301  1.000 84.08756  ? 139 SER   B O   1 
ATOM   4446 C  CB  . SER   B 2 56  ? 19.77606 16.58103  91.30004  1.000 89.14481  ? 139 SER   B CB  1 
ATOM   4447 O  OG  . SER   B 2 56  ? 19.69703 15.44838  90.45183  1.000 91.25440  ? 139 SER   B OG  1 
ATOM   4448 N  N   . LEU   B 2 57  ? 21.12866 17.66085  94.09537  1.000 83.04563  ? 140 LEU   B N   1 
ATOM   4449 C  CA  . LEU   B 2 57  ? 21.17489 18.70701  95.11174  1.000 79.40802  ? 140 LEU   B CA  1 
ATOM   4450 C  C   . LEU   B 2 57  ? 22.54798 19.37264  95.15845  1.000 72.48024  ? 140 LEU   B C   1 
ATOM   4451 O  O   . LEU   B 2 57  ? 22.65506 20.59699  95.33642  1.000 64.24663  ? 140 LEU   B O   1 
ATOM   4452 C  CB  . LEU   B 2 57  ? 20.80413 18.09332  96.46236  1.000 81.47655  ? 140 LEU   B CB  1 
ATOM   4453 C  CG  . LEU   B 2 57  ? 20.66971 18.92507  97.73184  1.000 82.40240  ? 140 LEU   B CG  1 
ATOM   4454 C  CD1 . LEU   B 2 57  ? 19.42823 18.49016  98.49135  1.000 92.19795  ? 140 LEU   B CD1 1 
ATOM   4455 C  CD2 . LEU   B 2 57  ? 21.89641 18.74082  98.59578  1.000 82.94454  ? 140 LEU   B CD2 1 
ATOM   4456 N  N   . ALA   B 2 58  ? 23.60948 18.57908  94.99249  1.000 78.49813  ? 141 ALA   B N   1 
ATOM   4457 C  CA  . ALA   B 2 58  ? 24.95595 19.13989  94.95030  1.000 71.00444  ? 141 ALA   B CA  1 
ATOM   4458 C  C   . ALA   B 2 58  ? 25.11358 20.10673  93.78334  1.000 68.96463  ? 141 ALA   B C   1 
ATOM   4459 O  O   . ALA   B 2 58  ? 25.71827 21.17509  93.93064  1.000 65.49905  ? 141 ALA   B O   1 
ATOM   4460 C  CB  . ALA   B 2 58  ? 25.98983 18.01740  94.86416  1.000 81.09062  ? 141 ALA   B CB  1 
ATOM   4461 N  N   . SER   B 2 59  ? 24.57495 19.75039  92.61369  1.000 74.75384  ? 142 SER   B N   1 
ATOM   4462 C  CA  . SER   B 2 59  ? 24.62421 20.65931  91.47309  1.000 68.00244  ? 142 SER   B CA  1 
ATOM   4463 C  C   . SER   B 2 59  ? 23.74227 21.88075  91.69388  1.000 68.15241  ? 142 SER   B C   1 
ATOM   4464 O  O   . SER   B 2 59  ? 24.05045 22.96607  91.18832  1.000 67.67662  ? 142 SER   B O   1 
ATOM   4465 C  CB  . SER   B 2 59  ? 24.20817 19.92826  90.19673  1.000 66.44849  ? 142 SER   B CB  1 
ATOM   4466 O  OG  . SER   B 2 59  ? 25.09123 18.85807  89.91020  1.000 79.93378  ? 142 SER   B OG  1 
ATOM   4467 N  N   . TYR   B 2 60  ? 22.64212 21.72131  92.43326  1.000 72.92666  ? 143 TYR   B N   1 
ATOM   4468 C  CA  . TYR   B 2 60  ? 21.80354 22.86818  92.76861  1.000 68.37629  ? 143 TYR   B CA  1 
ATOM   4469 C  C   . TYR   B 2 60  ? 22.57037 23.88956  93.59927  1.000 64.51907  ? 143 TYR   B C   1 
ATOM   4470 O  O   . TYR   B 2 60  ? 22.47622 25.09803  93.35354  1.000 60.90755  ? 143 TYR   B O   1 
ATOM   4471 C  CB  . TYR   B 2 60  ? 20.55678 22.41606  93.53244  1.000 75.54610  ? 143 TYR   B CB  1 
ATOM   4472 C  CG  . TYR   B 2 60  ? 19.44414 21.83208  92.68865  1.000 83.69854  ? 143 TYR   B CG  1 
ATOM   4473 C  CD1 . TYR   B 2 60  ? 19.65549 21.46864  91.36526  1.000 97.26147  ? 143 TYR   B CD1 1 
ATOM   4474 C  CD2 . TYR   B 2 60  ? 18.17221 21.65645  93.22050  1.000 80.69159  ? 143 TYR   B CD2 1 
ATOM   4475 C  CE1 . TYR   B 2 60  ? 18.63264 20.93519  90.59921  1.000 102.63733 ? 143 TYR   B CE1 1 
ATOM   4476 C  CE2 . TYR   B 2 60  ? 17.14548 21.12782  92.46358  1.000 89.55691  ? 143 TYR   B CE2 1 
ATOM   4477 C  CZ  . TYR   B 2 60  ? 17.38003 20.76888  91.15416  1.000 100.71173 ? 143 TYR   B CZ  1 
ATOM   4478 O  OH  . TYR   B 2 60  ? 16.35792 20.24192  90.39857  1.000 101.75725 ? 143 TYR   B OH  1 
ATOM   4479 N  N   . GLU   B 2 61  ? 23.33324 23.42013  94.59143  1.000 62.88484  ? 144 GLU   B N   1 
ATOM   4480 C  CA  . GLU   B 2 61  ? 23.90520 24.33950  95.57733  1.000 61.79709  ? 144 GLU   B CA  1 
ATOM   4481 C  C   . GLU   B 2 61  ? 24.95579 25.27357  94.97630  1.000 64.19147  ? 144 GLU   B C   1 
ATOM   4482 O  O   . GLU   B 2 61  ? 25.10585 26.41641  95.43874  1.000 65.21844  ? 144 GLU   B O   1 
ATOM   4483 C  CB  . GLU   B 2 61  ? 24.50762 23.55143  96.73953  1.000 62.33341  ? 144 GLU   B CB  1 
ATOM   4484 C  CG  . GLU   B 2 61  ? 24.51757 24.29825  98.06996  1.000 72.00950  ? 144 GLU   B CG  1 
ATOM   4485 C  CD  . GLU   B 2 61  ? 25.61846 25.33702  98.16298  1.000 74.91297  ? 144 GLU   B CD  1 
ATOM   4486 O  OE1 . GLU   B 2 61  ? 26.68226 25.13735  97.53890  1.000 73.51656  ? 144 GLU   B OE1 1 
ATOM   4487 O  OE2 . GLU   B 2 61  ? 25.41670 26.35642  98.85639  1.000 70.17018  ? 144 GLU   B OE2 1 
ATOM   4488 N  N   . LEU   B 2 62  ? 25.70098 24.81799  93.96557  1.000 66.65481  ? 145 LEU   B N   1 
ATOM   4489 C  CA  . LEU   B 2 62  ? 26.76693 25.66122  93.43683  1.000 65.73345  ? 145 LEU   B CA  1 
ATOM   4490 C  C   . LEU   B 2 62  ? 26.22844 26.90780  92.75008  1.000 62.09424  ? 145 LEU   B C   1 
ATOM   4491 O  O   . LEU   B 2 62  ? 26.94899 27.90292  92.66065  1.000 60.99217  ? 145 LEU   B O   1 
ATOM   4492 C  CB  . LEU   B 2 62  ? 27.67157 24.87145  92.48206  1.000 60.44773  ? 145 LEU   B CB  1 
ATOM   4493 C  CG  . LEU   B 2 62  ? 27.24198 24.38126  91.09526  1.000 55.62839  ? 145 LEU   B CG  1 
ATOM   4494 C  CD1 . LEU   B 2 62  ? 27.23764 25.48645  90.04659  1.000 43.14423  ? 145 LEU   B CD1 1 
ATOM   4495 C  CD2 . LEU   B 2 62  ? 28.17943 23.27681  90.66274  1.000 65.04709  ? 145 LEU   B CD2 1 
ATOM   4496 N  N   . ILE   B 2 63  ? 24.98255 26.88550  92.27441  1.000 62.12167  ? 146 ILE   B N   1 
ATOM   4497 C  CA  . ILE   B 2 63  ? 24.39642 28.09550  91.70699  1.000 64.02202  ? 146 ILE   B CA  1 
ATOM   4498 C  C   . ILE   B 2 63  ? 24.20744 29.15000  92.79067  1.000 63.85889  ? 146 ILE   B C   1 
ATOM   4499 O  O   . ILE   B 2 63  ? 24.50222 30.33350  92.58414  1.000 63.55874  ? 146 ILE   B O   1 
ATOM   4500 C  CB  . ILE   B 2 63  ? 23.07353 27.76378  90.99398  1.000 63.60296  ? 146 ILE   B CB  1 
ATOM   4501 C  CG1 . ILE   B 2 63  ? 23.31355 26.75110  89.87359  1.000 67.19044  ? 146 ILE   B CG1 1 
ATOM   4502 C  CG2 . ILE   B 2 63  ? 22.43037 29.02406  90.43837  1.000 58.18640  ? 146 ILE   B CG2 1 
ATOM   4503 C  CD1 . ILE   B 2 63  ? 24.24592 27.24999  88.78983  1.000 63.37814  ? 146 ILE   B CD1 1 
ATOM   4504 N  N   . CYS   B 2 64  ? 23.72893 28.73679  93.96746  1.000 65.91226  ? 147 CYS   B N   1 
ATOM   4505 C  CA  . CYS   B 2 64  ? 23.61213 29.66497  95.08846  1.000 68.52825  ? 147 CYS   B CA  1 
ATOM   4506 C  C   . CYS   B 2 64  ? 24.98254 30.16584  95.52932  1.000 65.74818  ? 147 CYS   B C   1 
ATOM   4507 O  O   . CYS   B 2 64  ? 25.14575 31.34626  95.87265  1.000 70.99702  ? 147 CYS   B O   1 
ATOM   4508 C  CB  . CYS   B 2 64  ? 22.88918 28.98787  96.25335  1.000 77.95873  ? 147 CYS   B CB  1 
ATOM   4509 S  SG  . CYS   B 2 64  ? 21.42471 28.03989  95.77852  1.000 90.17890  ? 147 CYS   B SG  1 
ATOM   4510 N  N   . SER   B 2 65  ? 25.98123 29.27922  95.52715  1.000 63.69237  ? 148 SER   B N   1 
ATOM   4511 C  CA  . SER   B 2 65  ? 27.33874 29.70043  95.87189  1.000 63.28847  ? 148 SER   B CA  1 
ATOM   4512 C  C   . SER   B 2 65  ? 27.86420 30.73482  94.87847  1.000 68.24457  ? 148 SER   B C   1 
ATOM   4513 O  O   . SER   B 2 65  ? 28.46988 31.74345  95.26784  1.000 73.95943  ? 148 SER   B O   1 
ATOM   4514 C  CB  . SER   B 2 65  ? 28.26477 28.48694  95.93064  1.000 56.49331  ? 148 SER   B CB  1 
ATOM   4515 O  OG  . SER   B 2 65  ? 27.91337 27.63374  97.00412  1.000 56.99001  ? 148 SER   B OG  1 
ATOM   4516 N  N   . LEU   B 2 66  ? 27.63885 30.49475  93.58432  1.000 58.27104  ? 149 LEU   B N   1 
ATOM   4517 C  CA  . LEU   B 2 66  ? 28.04619 31.44476  92.55543  1.000 54.28857  ? 149 LEU   B CA  1 
ATOM   4518 C  C   . LEU   B 2 66  ? 27.32481 32.77344  92.71322  1.000 55.41661  ? 149 LEU   B C   1 
ATOM   4519 O  O   . LEU   B 2 66  ? 27.91064 33.83552  92.48105  1.000 53.02731  ? 149 LEU   B O   1 
ATOM   4520 C  CB  . LEU   B 2 66  ? 27.77461 30.86488  91.16827  1.000 52.11807  ? 149 LEU   B CB  1 
ATOM   4521 C  CG  . LEU   B 2 66  ? 28.89570 30.08530  90.48638  1.000 46.94812  ? 149 LEU   B CG  1 
ATOM   4522 C  CD1 . LEU   B 2 66  ? 28.35119 29.29658  89.30810  1.000 46.79050  ? 149 LEU   B CD1 1 
ATOM   4523 C  CD2 . LEU   B 2 66  ? 29.98348 31.03804  90.02651  1.000 45.85904  ? 149 LEU   B CD2 1 
ATOM   4524 N  N   . GLN   B 2 67  ? 26.04611 32.73486  93.09353  1.000 58.28938  ? 150 GLN   B N   1 
ATOM   4525 C  CA  . GLN   B 2 67  ? 25.30073 33.97611  93.26996  1.000 59.90896  ? 150 GLN   B CA  1 
ATOM   4526 C  C   . GLN   B 2 67  ? 25.84551 34.78187  94.44159  1.000 69.32691  ? 150 GLN   B C   1 
ATOM   4527 O  O   . GLN   B 2 67  ? 25.98196 36.00773  94.34581  1.000 80.49269  ? 150 GLN   B O   1 
ATOM   4528 C  CB  . GLN   B 2 67  ? 23.81255 33.68597  93.46537  1.000 65.10591  ? 150 GLN   B CB  1 
ATOM   4529 C  CG  . GLN   B 2 67  ? 22.94392 34.93718  93.41749  1.000 70.68260  ? 150 GLN   B CG  1 
ATOM   4530 C  CD  . GLN   B 2 67  ? 22.98182 35.61959  92.06173  1.000 70.97234  ? 150 GLN   B CD  1 
ATOM   4531 O  OE1 . GLN   B 2 67  ? 23.22573 34.97927  91.03821  1.000 77.60620  ? 150 GLN   B OE1 1 
ATOM   4532 N  NE2 . GLN   B 2 67  ? 22.74384 36.92679  92.04898  1.000 67.75814  ? 150 GLN   B NE2 1 
ATOM   4533 N  N   . SER   B 2 68  ? 26.15281 34.11598  95.55955  1.000 64.44713  ? 151 SER   B N   1 
ATOM   4534 C  CA  . SER   B 2 68  ? 26.79794 34.82177  96.66387  1.000 62.87496  ? 151 SER   B CA  1 
ATOM   4535 C  C   . SER   B 2 68  ? 28.12524 35.42409  96.22525  1.000 69.71679  ? 151 SER   B C   1 
ATOM   4536 O  O   . SER   B 2 68  ? 28.41942 36.58635  96.53818  1.000 80.16802  ? 151 SER   B O   1 
ATOM   4537 C  CB  . SER   B 2 68  ? 26.99875 33.88751  97.85550  1.000 58.53571  ? 151 SER   B CB  1 
ATOM   4538 O  OG  . SER   B 2 68  ? 25.75637 33.40847  98.33106  1.000 63.64879  ? 151 SER   B OG  1 
ATOM   4539 N  N   . LEU   B 2 69  ? 28.94226 34.63979  95.51308  1.000 60.96025  ? 152 LEU   B N   1 
ATOM   4540 C  CA  . LEU   B 2 69  ? 30.20520 35.14608  94.98070  1.000 63.92309  ? 152 LEU   B CA  1 
ATOM   4541 C  C   . LEU   B 2 69  ? 29.99701 36.40396  94.14480  1.000 62.13473  ? 152 LEU   B C   1 
ATOM   4542 O  O   . LEU   B 2 69  ? 30.71121 37.39962  94.31199  1.000 60.37210  ? 152 LEU   B O   1 
ATOM   4543 C  CB  . LEU   B 2 69  ? 30.89024 34.06678  94.14081  1.000 62.19692  ? 152 LEU   B CB  1 
ATOM   4544 C  CG  . LEU   B 2 69  ? 32.07657 34.52191  93.28019  1.000 54.82593  ? 152 LEU   B CG  1 
ATOM   4545 C  CD1 . LEU   B 2 69  ? 33.19562 35.07532  94.14819  1.000 55.82836  ? 152 LEU   B CD1 1 
ATOM   4546 C  CD2 . LEU   B 2 69  ? 32.58476 33.38445  92.40372  1.000 59.30905  ? 152 LEU   B CD2 1 
ATOM   4547 N  N   . ILE   B 2 70  ? 29.03505 36.36850  93.22035  1.000 58.68187  ? 153 ILE   B N   1 
ATOM   4548 C  CA  . ILE   B 2 70  ? 28.85073 37.49106  92.30597  1.000 58.86071  ? 153 ILE   B CA  1 
ATOM   4549 C  C   . ILE   B 2 70  ? 28.32667 38.70796  93.05559  1.000 61.31131  ? 153 ILE   B C   1 
ATOM   4550 O  O   . ILE   B 2 70  ? 28.69308 39.84801  92.74571  1.000 61.66316  ? 153 ILE   B O   1 
ATOM   4551 C  CB  . ILE   B 2 70  ? 27.92903 37.09379  91.13778  1.000 57.86817  ? 153 ILE   B CB  1 
ATOM   4552 C  CG1 . ILE   B 2 70  ? 28.58522 35.99823  90.29965  1.000 53.69944  ? 153 ILE   B CG1 1 
ATOM   4553 C  CG2 . ILE   B 2 70  ? 27.63030 38.29671  90.25347  1.000 62.96094  ? 153 ILE   B CG2 1 
ATOM   4554 C  CD1 . ILE   B 2 70  ? 27.69179 35.42345  89.23462  1.000 61.19657  ? 153 ILE   B CD1 1 
ATOM   4555 N  N   . ILE   B 2 71  ? 27.47809 38.49074  94.06318  1.000 62.69599  ? 154 ILE   B N   1 
ATOM   4556 C  CA  . ILE   B 2 71  ? 27.01849 39.60536  94.88783  1.000 64.56645  ? 154 ILE   B CA  1 
ATOM   4557 C  C   . ILE   B 2 71  ? 28.19415 40.24269  95.61617  1.000 66.93271  ? 154 ILE   B C   1 
ATOM   4558 O  O   . ILE   B 2 71  ? 28.30840 41.47364  95.69258  1.000 68.18444  ? 154 ILE   B O   1 
ATOM   4559 C  CB  . ILE   B 2 71  ? 25.92700 39.13221  95.86651  1.000 66.59788  ? 154 ILE   B CB  1 
ATOM   4560 C  CG1 . ILE   B 2 71  ? 24.66278 38.75288  95.09609  1.000 66.59378  ? 154 ILE   B CG1 1 
ATOM   4561 C  CG2 . ILE   B 2 71  ? 25.61148 40.21146  96.89520  1.000 73.31435  ? 154 ILE   B CG2 1 
ATOM   4562 C  CD1 . ILE   B 2 71  ? 23.55888 38.17541  95.95748  1.000 62.87055  ? 154 ILE   B CD1 1 
ATOM   4563 N  N   . SER   B 2 72  ? 29.09482 39.41495  96.14869  1.000 64.90780  ? 155 SER   B N   1 
ATOM   4564 C  CA  . SER   B 2 72  ? 30.26648 39.94374  96.83926  1.000 69.98754  ? 155 SER   B CA  1 
ATOM   4565 C  C   . SER   B 2 72  ? 31.17460 40.70651  95.87967  1.000 65.55306  ? 155 SER   B C   1 
ATOM   4566 O  O   . SER   B 2 72  ? 31.73036 41.75260  96.23799  1.000 65.96004  ? 155 SER   B O   1 
ATOM   4567 C  CB  . SER   B 2 72  ? 31.02761 38.80555  97.52416  1.000 70.47087  ? 155 SER   B CB  1 
ATOM   4568 O  OG  . SER   B 2 72  ? 30.24913 38.19542  98.54286  1.000 78.82128  ? 155 SER   B OG  1 
ATOM   4569 N  N   . VAL   B 2 73  ? 31.32504 40.20749  94.65133  1.000 60.28530  ? 156 VAL   B N   1 
ATOM   4570 C  CA  . VAL   B 2 73  ? 32.16207 40.89780  93.67388  1.000 60.15141  ? 156 VAL   B CA  1 
ATOM   4571 C  C   . VAL   B 2 73  ? 31.54084 42.23536  93.28557  1.000 65.72096  ? 156 VAL   B C   1 
ATOM   4572 O  O   . VAL   B 2 73  ? 32.24868 43.23397  93.10682  1.000 64.27829  ? 156 VAL   B O   1 
ATOM   4573 C  CB  . VAL   B 2 73  ? 32.40851 40.00610  92.44392  1.000 56.21748  ? 156 VAL   B CB  1 
ATOM   4574 C  CG1 . VAL   B 2 73  ? 33.20338 40.76798  91.40052  1.000 63.26708  ? 156 VAL   B CG1 1 
ATOM   4575 C  CG2 . VAL   B 2 73  ? 33.15128 38.74413  92.84743  1.000 66.01844  ? 156 VAL   B CG2 1 
ATOM   4576 N  N   . GLU   B 2 74  ? 30.21225 42.28219  93.15384  1.000 67.83094  ? 157 GLU   B N   1 
ATOM   4577 C  CA  . GLU   B 2 74  ? 29.54574 43.55309  92.88295  1.000 69.85066  ? 157 GLU   B CA  1 
ATOM   4578 C  C   . GLU   B 2 74  ? 29.73390 44.52752  94.03796  1.000 73.90350  ? 157 GLU   B C   1 
ATOM   4579 O  O   . GLU   B 2 74  ? 29.94011 45.72737  93.82145  1.000 77.12485  ? 157 GLU   B O   1 
ATOM   4580 C  CB  . GLU   B 2 74  ? 28.05799 43.32740  92.61765  1.000 70.41137  ? 157 GLU   B CB  1 
ATOM   4581 C  CG  . GLU   B 2 74  ? 27.75980 42.52219  91.36952  1.000 71.82952  ? 157 GLU   B CG  1 
ATOM   4582 C  CD  . GLU   B 2 74  ? 26.30337 42.11605  91.27966  1.000 81.19354  ? 157 GLU   B CD  1 
ATOM   4583 O  OE1 . GLU   B 2 74  ? 25.49168 42.64057  92.07054  1.000 85.68406  ? 157 GLU   B OE1 1 
ATOM   4584 O  OE2 . GLU   B 2 74  ? 25.97050 41.26940  90.42403  1.000 91.92278  ? 157 GLU   B OE2 1 
ATOM   4585 N  N   . GLN   B 2 75  ? 29.65904 44.02993  95.27463  1.000 71.47498  ? 158 GLN   B N   1 
ATOM   4586 C  CA  . GLN   B 2 75  ? 29.88885 44.89150  96.43049  1.000 74.98495  ? 158 GLN   B CA  1 
ATOM   4587 C  C   . GLN   B 2 75  ? 31.30950 45.44054  96.43206  1.000 75.76228  ? 158 GLN   B C   1 
ATOM   4588 O  O   . GLN   B 2 75  ? 31.53362 46.60687  96.77701  1.000 88.62880  ? 158 GLN   B O   1 
ATOM   4589 C  CB  . GLN   B 2 75  ? 29.61029 44.12453  97.72296  1.000 73.32799  ? 158 GLN   B CB  1 
ATOM   4590 C  CG  . GLN   B 2 75  ? 28.16011 43.71958  97.90512  1.000 73.93130  ? 158 GLN   B CG  1 
ATOM   4591 C  CD  . GLN   B 2 75  ? 27.94836 42.86967  99.13935  1.000 72.41131  ? 158 GLN   B CD  1 
ATOM   4592 O  OE1 . GLN   B 2 75  ? 28.89344 42.56993  99.86916  1.000 68.48427  ? 158 GLN   B OE1 1 
ATOM   4593 N  NE2 . GLN   B 2 75  ? 26.70390 42.47424  99.37978  1.000 73.23604  ? 158 GLN   B NE2 1 
ATOM   4594 N  N   . LEU   B 2 76  ? 32.28302 44.61321  96.04577  1.000 64.29862  ? 159 LEU   B N   1 
ATOM   4595 C  CA  . LEU   B 2 76  ? 33.66784 45.07313  96.01151  1.000 68.43299  ? 159 LEU   B CA  1 
ATOM   4596 C  C   . LEU   B 2 76  ? 33.92092 46.03125  94.85340  1.000 77.78175  ? 159 LEU   B C   1 
ATOM   4597 O  O   . LEU   B 2 76  ? 34.80859 46.88706  94.94482  1.000 82.22658  ? 159 LEU   B O   1 
ATOM   4598 C  CB  . LEU   B 2 76  ? 34.61829 43.87961  95.93212  1.000 65.32151  ? 159 LEU   B CB  1 
ATOM   4599 C  CG  . LEU   B 2 76  ? 34.76378 43.06286  97.21659  1.000 67.79687  ? 159 LEU   B CG  1 
ATOM   4600 C  CD1 . LEU   B 2 76  ? 35.67712 41.86853  96.99333  1.000 54.06922  ? 159 LEU   B CD1 1 
ATOM   4601 C  CD2 . LEU   B 2 76  ? 35.28757 43.93802  98.34527  1.000 70.10277  ? 159 LEU   B CD2 1 
ATOM   4602 N  N   . GLN   B 2 77  ? 33.16203 45.90619  93.76160  1.000 75.58925  ? 160 GLN   B N   1 
ATOM   4603 C  CA  . GLN   B 2 77  ? 33.33408 46.82339  92.63832  1.000 78.11083  ? 160 GLN   B CA  1 
ATOM   4604 C  C   . GLN   B 2 77  ? 32.84973 48.22571  92.98477  1.000 82.59838  ? 160 GLN   B C   1 
ATOM   4605 O  O   . GLN   B 2 77  ? 33.42542 49.21841  92.52351  1.000 87.86069  ? 160 GLN   B O   1 
ATOM   4606 C  CB  . GLN   B 2 77  ? 32.59542 46.30045  91.40681  1.000 72.81343  ? 160 GLN   B CB  1 
ATOM   4607 C  CG  . GLN   B 2 77  ? 33.40396 45.35595  90.53776  1.000 77.26327  ? 160 GLN   B CG  1 
ATOM   4608 C  CD  . GLN   B 2 77  ? 32.70038 45.03047  89.23488  1.000 83.20189  ? 160 GLN   B CD  1 
ATOM   4609 O  OE1 . GLN   B 2 77  ? 31.47782 45.13712  89.13323  1.000 77.50556  ? 160 GLN   B OE1 1 
ATOM   4610 N  NE2 . GLN   B 2 77  ? 33.47134 44.63953  88.22683  1.000 92.29124  ? 160 GLN   B NE2 1 
ATOM   4611 N  N   . ALA   B 2 78  ? 31.78978 48.32775  93.79051  1.000 79.18832  ? 161 ALA   B N   1 
ATOM   4612 C  CA  . ALA   B 2 78  ? 31.22928 49.63505  94.11471  1.000 81.08818  ? 161 ALA   B CA  1 
ATOM   4613 C  C   . ALA   B 2 78  ? 32.18853 50.47244  94.94971  1.000 81.77164  ? 161 ALA   B C   1 
ATOM   4614 O  O   . ALA   B 2 78  ? 32.16904 51.70547  94.86207  1.000 88.47005  ? 161 ALA   B O   1 
ATOM   4615 C  CB  . ALA   B 2 78  ? 29.89680 49.46809  94.84390  1.000 79.21211  ? 161 ALA   B CB  1 
ATOM   4616 N  N   . SER   B 2 79  ? 33.02970 49.83036  95.75700  1.000 79.81203  ? 162 SER   B N   1 
ATOM   4617 C  CA  . SER   B 2 79  ? 33.99312 50.53899  96.58677  1.000 89.32885  ? 162 SER   B CA  1 
ATOM   4618 C  C   . SER   B 2 79  ? 35.31080 50.80880  95.87384  1.000 91.61919  ? 162 SER   B C   1 
ATOM   4619 O  O   . SER   B 2 79  ? 36.13188 51.57040  96.39752  1.000 90.87617  ? 162 SER   B O   1 
ATOM   4620 C  CB  . SER   B 2 79  ? 34.26340 49.74849  97.87094  1.000 90.79133  ? 162 SER   B CB  1 
ATOM   4621 O  OG  . SER   B 2 79  ? 33.06692 49.54391  98.60164  1.000 86.04176  ? 162 SER   B OG  1 
ATOM   4622 N  N   . PHE   B 2 80  ? 35.52511 50.20865  94.70030  1.000 90.68825  ? 163 PHE   B N   1 
ATOM   4623 C  CA  . PHE   B 2 80  ? 36.76745 50.35978  93.93975  1.000 95.74819  ? 163 PHE   B CA  1 
ATOM   4624 C  C   . PHE   B 2 80  ? 37.97989 49.97044  94.78192  1.000 95.00050  ? 163 PHE   B C   1 
ATOM   4625 O  O   . PHE   B 2 80  ? 39.00998 50.64714  94.77946  1.000 94.34965  ? 163 PHE   B O   1 
ATOM   4626 C  CB  . PHE   B 2 80  ? 36.91029 51.77865  93.38594  1.000 100.33790 ? 163 PHE   B CB  1 
ATOM   4627 C  CG  . PHE   B 2 80  ? 35.76805 52.19700  92.50578  1.000 100.22097 ? 163 PHE   B CG  1 
ATOM   4628 C  CD1 . PHE   B 2 80  ? 35.58768 51.61399  91.26228  1.000 98.05909  ? 163 PHE   B CD1 1 
ATOM   4629 C  CD2 . PHE   B 2 80  ? 34.87203 53.16752  92.92224  1.000 96.49598  ? 163 PHE   B CD2 1 
ATOM   4630 C  CE1 . PHE   B 2 80  ? 34.53603 51.99141  90.44944  1.000 100.47575 ? 163 PHE   B CE1 1 
ATOM   4631 C  CE2 . PHE   B 2 80  ? 33.81855 53.55064  92.11374  1.000 98.01403  ? 163 PHE   B CE2 1 
ATOM   4632 C  CZ  . PHE   B 2 80  ? 33.65053 52.96162  90.87548  1.000 104.79022 ? 163 PHE   B CZ  1 
ATOM   4633 N  N   . LEU   B 2 81  ? 37.84520 48.87186  95.51818  1.000 86.61359  ? 164 LEU   B N   1 
ATOM   4634 C  CA  . LEU   B 2 81  ? 38.93007 48.31684  96.31634  1.000 87.26261  ? 164 LEU   B CA  1 
ATOM   4635 C  C   . LEU   B 2 81  ? 39.65359 47.26061  95.49077  1.000 85.61281  ? 164 LEU   B C   1 
ATOM   4636 O  O   . LEU   B 2 81  ? 39.05254 46.25539  95.09811  1.000 81.56031  ? 164 LEU   B O   1 
ATOM   4637 C  CB  . LEU   B 2 81  ? 38.38627 47.71900  97.61219  1.000 80.16886  ? 164 LEU   B CB  1 
ATOM   4638 C  CG  . LEU   B 2 81  ? 39.31029 46.81070  98.41776  1.000 88.93775  ? 164 LEU   B CG  1 
ATOM   4639 C  CD1 . LEU   B 2 81  ? 40.45273 47.59958  99.04202  1.000 84.69767  ? 164 LEU   B CD1 1 
ATOM   4640 C  CD2 . LEU   B 2 81  ? 38.50177 46.08597  99.47651  1.000 91.09000  ? 164 LEU   B CD2 1 
ATOM   4641 N  N   . LEU   B 2 82  ? 40.94065 47.48419  95.23319  1.000 82.58064  ? 165 LEU   B N   1 
ATOM   4642 C  CA  . LEU   B 2 82  ? 41.68652 46.65698  94.29582  1.000 80.11291  ? 165 LEU   B CA  1 
ATOM   4643 C  C   . LEU   B 2 82  ? 42.50610 45.55829  94.96641  1.000 81.39540  ? 165 LEU   B C   1 
ATOM   4644 O  O   . LEU   B 2 82  ? 43.06896 44.71384  94.26057  1.000 84.90156  ? 165 LEU   B O   1 
ATOM   4645 C  CB  . LEU   B 2 82  ? 42.60285 47.53876  93.43077  1.000 82.47161  ? 165 LEU   B CB  1 
ATOM   4646 C  CG  . LEU   B 2 82  ? 42.00359 48.22231  92.18960  1.000 80.48003  ? 165 LEU   B CG  1 
ATOM   4647 C  CD1 . LEU   B 2 82  ? 40.84342 49.14930  92.53095  1.000 84.95686  ? 165 LEU   B CD1 1 
ATOM   4648 C  CD2 . LEU   B 2 82  ? 43.07462 48.98511  91.41827  1.000 89.90214  ? 165 LEU   B CD2 1 
ATOM   4649 N  N   . ASN   B 2 83  ? 42.58110 45.53609  96.29619  1.000 77.25930  ? 166 ASN   B N   1 
ATOM   4650 C  CA  . ASN   B 2 83  ? 43.30284 44.48652  97.02025  1.000 84.09668  ? 166 ASN   B CA  1 
ATOM   4651 C  C   . ASN   B 2 83  ? 42.59972 44.23661  98.34486  1.000 82.35478  ? 166 ASN   B C   1 
ATOM   4652 O  O   . ASN   B 2 83  ? 42.99179 44.76671  99.39267  1.000 84.25670  ? 166 ASN   B O   1 
ATOM   4653 C  CB  . ASN   B 2 83  ? 44.76835 44.86987  97.23748  1.000 92.91532  ? 166 ASN   B CB  1 
ATOM   4654 C  CG  . ASN   B 2 83  ? 45.66536 43.66450  97.48790  1.000 95.94297  ? 166 ASN   B CG  1 
ATOM   4655 O  OD1 . ASN   B 2 83  ? 45.23646 42.65739  98.04838  1.000 96.31730  ? 166 ASN   B OD1 1 
ATOM   4656 N  ND2 . ASN   B 2 83  ? 46.92266 43.76788  97.06681  1.000 91.07567  ? 166 ASN   B ND2 1 
ATOM   4657 N  N   . PRO   B 2 84  ? 41.53886 43.42256  98.33853  1.000 77.01437  ? 167 PRO   B N   1 
ATOM   4658 C  CA  . PRO   B 2 84  ? 40.76264 43.21469  99.56975  1.000 71.12374  ? 167 PRO   B CA  1 
ATOM   4659 C  C   . PRO   B 2 84  ? 41.41939 42.24497  100.54407 1.000 73.51741  ? 167 PRO   B C   1 
ATOM   4660 O  O   . PRO   B 2 84  ? 40.79686 41.83897  101.53306 1.000 78.77749  ? 167 PRO   B O   1 
ATOM   4661 C  CB  . PRO   B 2 84  ? 39.42884 42.65532  99.05079  1.000 72.41246  ? 167 PRO   B CB  1 
ATOM   4662 C  CG  . PRO   B 2 84  ? 39.40780 42.98698  97.57432  1.000 77.47892  ? 167 PRO   B CG  1 
ATOM   4663 C  CD  . PRO   B 2 84  ? 40.84089 42.87675  97.16353  1.000 82.15753  ? 167 PRO   B CD  1 
ATOM   4664 N  N   . GLU   B 2 85  ? 42.67799 41.87411  100.28036 1.000 78.38246  ? 168 GLU   B N   1 
ATOM   4665 C  CA  . GLU   B 2 85  ? 43.36130 40.89650  101.12252 1.000 80.64918  ? 168 GLU   B CA  1 
ATOM   4666 C  C   . GLU   B 2 85  ? 43.49598 41.38199  102.55961 1.000 78.75973  ? 168 GLU   B C   1 
ATOM   4667 O  O   . GLU   B 2 85  ? 43.44477 40.57473  103.49371 1.000 82.42685  ? 168 GLU   B O   1 
ATOM   4668 C  CB  . GLU   B 2 85  ? 44.73629 40.57775  100.54049 1.000 81.54304  ? 168 GLU   B CB  1 
ATOM   4669 N  N   . LYS   B 2 86  ? 43.66550 42.68836  102.75743 1.000 73.43108  ? 169 LYS   B N   1 
ATOM   4670 C  CA  . LYS   B 2 86  ? 43.75118 43.27466  104.08765 1.000 76.88694  ? 169 LYS   B CA  1 
ATOM   4671 C  C   . LYS   B 2 86  ? 42.38852 43.57604  104.69684 1.000 78.95708  ? 169 LYS   B C   1 
ATOM   4672 O  O   . LYS   B 2 86  ? 42.30678 43.81289  105.90699 1.000 85.86946  ? 169 LYS   B O   1 
ATOM   4673 C  CB  . LYS   B 2 86  ? 44.58069 44.56207  104.04124 1.000 76.57630  ? 169 LYS   B CB  1 
ATOM   4674 N  N   . TYR   B 2 87  ? 41.32370 43.58141  103.89500 1.000 72.89529  ? 170 TYR   B N   1 
ATOM   4675 C  CA  . TYR   B 2 87  ? 39.98167 43.87686  104.38525 1.000 69.07732  ? 170 TYR   B CA  1 
ATOM   4676 C  C   . TYR   B 2 87  ? 39.13711 42.61600  104.53635 1.000 74.22036  ? 170 TYR   B C   1 
ATOM   4677 O  O   . TYR   B 2 87  ? 38.70972 42.28044  105.64478 1.000 76.69813  ? 170 TYR   B O   1 
ATOM   4678 C  CB  . TYR   B 2 87  ? 39.28341 44.87414  103.45002 1.000 69.60804  ? 170 TYR   B CB  1 
ATOM   4679 C  CG  . TYR   B 2 87  ? 39.79963 46.29295  103.55114 1.000 77.31865  ? 170 TYR   B CG  1 
ATOM   4680 C  CD1 . TYR   B 2 87  ? 40.55019 46.70682  104.64328 1.000 90.10380  ? 170 TYR   B CD1 1 
ATOM   4681 C  CD2 . TYR   B 2 87  ? 39.52761 47.22134  102.55586 1.000 70.38914  ? 170 TYR   B CD2 1 
ATOM   4682 C  CE1 . TYR   B 2 87  ? 41.01886 48.00514  104.73698 1.000 86.76124  ? 170 TYR   B CE1 1 
ATOM   4683 C  CE2 . TYR   B 2 87  ? 39.99228 48.51924  102.63914 1.000 76.49178  ? 170 TYR   B CE2 1 
ATOM   4684 C  CZ  . TYR   B 2 87  ? 40.73699 48.90662  103.73160 1.000 87.13150  ? 170 TYR   B CZ  1 
ATOM   4685 O  OH  . TYR   B 2 87  ? 41.20151 50.19932  103.81885 1.000 96.46251  ? 170 TYR   B OH  1 
ATOM   4686 N  N   . THR   B 2 88  ? 38.88569 41.91009  103.43577 1.000 79.59936  ? 171 THR   B N   1 
ATOM   4687 C  CA  . THR   B 2 88  ? 37.98670 40.76234  103.42247 1.000 73.19991  ? 171 THR   B CA  1 
ATOM   4688 C  C   . THR   B 2 88  ? 38.73509 39.53410  102.92703 1.000 76.88477  ? 171 THR   B C   1 
ATOM   4689 O  O   . THR   B 2 88  ? 39.26260 39.53242  101.80954 1.000 75.99551  ? 171 THR   B O   1 
ATOM   4690 C  CB  . THR   B 2 88  ? 36.76830 41.02802  102.53507 1.000 65.38829  ? 171 THR   B CB  1 
ATOM   4691 O  OG1 . THR   B 2 88  ? 37.19202 41.18262  101.17482 1.000 64.30270  ? 171 THR   B OG1 1 
ATOM   4692 C  CG2 . THR   B 2 88  ? 36.05100 42.29073  102.97765 1.000 72.42307  ? 171 THR   B CG2 1 
ATOM   4693 N  N   . ASP   B 2 89  ? 38.77254 38.48956  103.75562 1.000 76.83451  ? 172 ASP   B N   1 
ATOM   4694 C  CA  . ASP   B 2 89  ? 39.29091 37.20074  103.31735 1.000 74.14892  ? 172 ASP   B CA  1 
ATOM   4695 C  C   . ASP   B 2 89  ? 38.31636 36.46082  102.41163 1.000 76.29018  ? 172 ASP   B C   1 
ATOM   4696 O  O   . ASP   B 2 89  ? 38.69357 35.43774  101.83077 1.000 85.08829  ? 172 ASP   B O   1 
ATOM   4697 C  CB  . ASP   B 2 89  ? 39.62969 36.33220  104.53104 1.000 73.93392  ? 172 ASP   B CB  1 
ATOM   4698 C  CG  . ASP   B 2 89  ? 38.45338 36.16652  105.47787 1.000 79.46007  ? 172 ASP   B CG  1 
ATOM   4699 O  OD1 . ASP   B 2 89  ? 37.47752 35.47899  105.10863 1.000 70.29774  ? 172 ASP   B OD1 1 
ATOM   4700 O  OD2 . ASP   B 2 89  ? 38.50567 36.72306  106.59490 1.000 99.19812  ? 172 ASP   B OD2 1 
ATOM   4701 N  N   . GLU   B 2 90  ? 37.08406 36.96086  102.27557 1.000 71.52050  ? 173 GLU   B N   1 
ATOM   4702 C  CA  . GLU   B 2 90  ? 36.05484 36.26140  101.51149 1.000 75.52977  ? 173 GLU   B CA  1 
ATOM   4703 C  C   . GLU   B 2 90  ? 36.45780 36.06375  100.05521 1.000 73.57472  ? 173 GLU   B C   1 
ATOM   4704 O  O   . GLU   B 2 90  ? 36.09669 35.04728  99.44247  1.000 75.03394  ? 173 GLU   B O   1 
ATOM   4705 C  CB  . GLU   B 2 90  ? 34.73867 37.03454  101.60587 1.000 66.84948  ? 173 GLU   B CB  1 
ATOM   4706 C  CG  . GLU   B 2 90  ? 33.58417 36.42941  100.83150 1.000 68.18051  ? 173 GLU   B CG  1 
ATOM   4707 C  CD  . GLU   B 2 90  ? 32.28974 37.18769  101.04417 1.000 72.79837  ? 173 GLU   B CD  1 
ATOM   4708 O  OE1 . GLU   B 2 90  ? 32.20894 37.96615  102.01802 1.000 81.90543  ? 173 GLU   B OE1 1 
ATOM   4709 O  OE2 . GLU   B 2 90  ? 31.35431 37.00810  100.23728 1.000 83.22707  ? 173 GLU   B OE2 1 
ATOM   4710 N  N   . LEU   B 2 91  ? 37.21487 37.01399  99.49466  1.000 59.05691  ? 174 LEU   B N   1 
ATOM   4711 C  CA  . LEU   B 2 91  ? 37.64024 36.92531  98.10086  1.000 65.21804  ? 174 LEU   B CA  1 
ATOM   4712 C  C   . LEU   B 2 91  ? 38.39543 35.63298  97.82046  1.000 68.85856  ? 174 LEU   B C   1 
ATOM   4713 O  O   . LEU   B 2 91  ? 38.38073 35.13829  96.68759  1.000 69.24151  ? 174 LEU   B O   1 
ATOM   4714 C  CB  . LEU   B 2 91  ? 38.50694 38.13466  97.74554  1.000 70.33315  ? 174 LEU   B CB  1 
ATOM   4715 C  CG  . LEU   B 2 91  ? 38.86652 38.33618  96.27226  1.000 70.10010  ? 174 LEU   B CG  1 
ATOM   4716 C  CD1 . LEU   B 2 91  ? 37.61548 38.60155  95.45366  1.000 62.83839  ? 174 LEU   B CD1 1 
ATOM   4717 C  CD2 . LEU   B 2 91  ? 39.86567 39.47125  96.11237  1.000 72.32933  ? 174 LEU   B CD2 1 
ATOM   4718 N  N   . ALA   B 2 92  ? 39.05477 35.07198  98.83155  1.000 69.02828  ? 175 ALA   B N   1 
ATOM   4719 C  CA  . ALA   B 2 92  ? 39.74256 33.79687  98.69070  1.000 70.19244  ? 175 ALA   B CA  1 
ATOM   4720 C  C   . ALA   B 2 92  ? 38.94466 32.62081  99.23321  1.000 77.33141  ? 175 ALA   B C   1 
ATOM   4721 O  O   . ALA   B 2 92  ? 39.12506 31.49645  98.75650  1.000 83.36670  ? 175 ALA   B O   1 
ATOM   4722 C  CB  . ALA   B 2 92  ? 41.10365 33.84705  99.39318  1.000 75.84156  ? 175 ALA   B CB  1 
ATOM   4723 N  N   . THR   B 2 93  ? 38.06152 32.84806  100.20998 1.000 75.25638  ? 176 THR   B N   1 
ATOM   4724 C  CA  . THR   B 2 93  ? 37.31033 31.73885  100.79094 1.000 70.10265  ? 176 THR   B CA  1 
ATOM   4725 C  C   . THR   B 2 93  ? 36.19576 31.25840  99.86838  1.000 64.90660  ? 176 THR   B C   1 
ATOM   4726 O  O   . THR   B 2 93  ? 35.84438 30.07307  99.89426  1.000 67.62090  ? 176 THR   B O   1 
ATOM   4727 C  CB  . THR   B 2 93  ? 36.72294 32.13667  102.14598 1.000 67.92815  ? 176 THR   B CB  1 
ATOM   4728 O  OG1 . THR   B 2 93  ? 35.73726 33.15868  101.96271 1.000 65.21175  ? 176 THR   B OG1 1 
ATOM   4729 C  CG2 . THR   B 2 93  ? 37.81201 32.65017  103.07733 1.000 72.52548  ? 176 THR   B CG2 1 
ATOM   4730 N  N   . GLN   B 2 94  ? 35.62667 32.15026  99.05268  1.000 64.67056  ? 177 GLN   B N   1 
ATOM   4731 C  CA  . GLN   B 2 94  ? 34.53215 31.75212  98.16891  1.000 66.89332  ? 177 GLN   B CA  1 
ATOM   4732 C  C   . GLN   B 2 94  ? 34.98871 30.79466  97.06405  1.000 63.87283  ? 177 GLN   B C   1 
ATOM   4733 O  O   . GLN   B 2 94  ? 34.28149 29.81573  96.77462  1.000 59.94406  ? 177 GLN   B O   1 
ATOM   4734 C  CB  . GLN   B 2 94  ? 33.85819 32.98520  97.56049  1.000 66.84291  ? 177 GLN   B CB  1 
ATOM   4735 C  CG  . GLN   B 2 94  ? 32.51976 32.68501  96.92339  1.000 72.89816  ? 177 GLN   B CG  1 
ATOM   4736 C  CD  . GLN   B 2 94  ? 31.36361 33.20233  97.75110  1.000 71.25518  ? 177 GLN   B CD  1 
ATOM   4737 O  OE1 . GLN   B 2 94  ? 30.39015 32.49044  98.00414  1.000 76.99573  ? 177 GLN   B OE1 1 
ATOM   4738 N  NE2 . GLN   B 2 94  ? 31.46614 34.45269  98.18055  1.000 59.35916  ? 177 GLN   B NE2 1 
ATOM   4739 N  N   . PRO   B 2 95  ? 36.13080 31.03628  96.40336  1.000 66.15470  ? 178 PRO   B N   1 
ATOM   4740 C  CA  . PRO   B 2 95  ? 36.60459 30.05411  95.41479  1.000 57.97936  ? 178 PRO   B CA  1 
ATOM   4741 C  C   . PRO   B 2 95  ? 36.79442 28.65807  95.98118  1.000 62.24656  ? 178 PRO   B C   1 
ATOM   4742 O  O   . PRO   B 2 95  ? 36.56114 27.68053  95.26506  1.000 67.73719  ? 178 PRO   B O   1 
ATOM   4743 C  CB  . PRO   B 2 95  ? 37.93123 30.65821  94.93530  1.000 64.38089  ? 178 PRO   B CB  1 
ATOM   4744 C  CG  . PRO   B 2 95  ? 37.73383 32.12110  95.08421  1.000 70.86738  ? 178 PRO   B CG  1 
ATOM   4745 C  CD  . PRO   B 2 95  ? 36.94356 32.26741  96.35543  1.000 69.60027  ? 178 PRO   B CD  1 
ATOM   4746 N  N   . ARG   B 2 96  ? 37.21100 28.52665  97.24198  1.000 62.56321  ? 179 ARG   B N   1 
ATOM   4747 C  CA  . ARG   B 2 96  ? 37.29904 27.20099  97.85108  1.000 62.86172  ? 179 ARG   B CA  1 
ATOM   4748 C  C   . ARG   B 2 96  ? 35.91371 26.59031  98.03576  1.000 59.21597  ? 179 ARG   B C   1 
ATOM   4749 O  O   . ARG   B 2 96  ? 35.72102 25.38279  97.82922  1.000 62.39281  ? 179 ARG   B O   1 
ATOM   4750 C  CB  . ARG   B 2 96  ? 38.03059 27.28397  99.19269  1.000 65.79435  ? 179 ARG   B CB  1 
ATOM   4751 C  CG  . ARG   B 2 96  ? 39.55411 27.25861  99.10436  1.000 81.39373  ? 179 ARG   B CG  1 
ATOM   4752 C  CD  . ARG   B 2 96  ? 40.11176 28.50821  98.44244  1.000 86.11095  ? 179 ARG   B CD  1 
ATOM   4753 N  NE  . ARG   B 2 96  ? 41.54993 28.64764  98.63614  1.000 96.72202  ? 179 ARG   B NE  1 
ATOM   4754 C  CZ  . ARG   B 2 96  ? 42.10912 29.39648  99.57705  1.000 97.52436  ? 179 ARG   B CZ  1 
ATOM   4755 N  NH1 . ARG   B 2 96  ? 41.37810 30.09410  100.43119 1.000 92.40621  ? 179 ARG   B NH1 1 
ATOM   4756 N  NH2 . ARG   B 2 96  ? 43.43509 29.44883  99.66174  1.000 100.64552 ? 179 ARG   B NH2 1 
ATOM   4757 N  N   . ARG   B 2 97  ? 34.94082 27.41585  98.43162  1.000 58.20767  ? 180 ARG   B N   1 
ATOM   4758 C  CA  . ARG   B 2 97  ? 33.56180 26.95722  98.56045  1.000 61.39418  ? 180 ARG   B CA  1 
ATOM   4759 C  C   . ARG   B 2 97  ? 33.03691 26.41875  97.23633  1.000 63.21446  ? 180 ARG   B C   1 
ATOM   4760 O  O   . ARG   B 2 97  ? 32.27343 25.44606  97.21039  1.000 60.41844  ? 180 ARG   B O   1 
ATOM   4761 C  CB  . ARG   B 2 97  ? 32.68805 28.10636  99.06669  1.000 73.66385  ? 180 ARG   B CB  1 
ATOM   4762 C  CG  . ARG   B 2 97  ? 31.20217 27.80871  99.17783  1.000 69.54765  ? 180 ARG   B CG  1 
ATOM   4763 C  CD  . ARG   B 2 97  ? 30.44835 29.08166  99.53893  1.000 70.61678  ? 180 ARG   B CD  1 
ATOM   4764 N  NE  . ARG   B 2 97  ? 29.02680 28.85497  99.76728  1.000 72.26825  ? 180 ARG   B NE  1 
ATOM   4765 C  CZ  . ARG   B 2 97  ? 28.16032 29.80944  100.07879 1.000 74.27879  ? 180 ARG   B CZ  1 
ATOM   4766 N  NH1 . ARG   B 2 97  ? 28.53678 31.07237  100.19972 1.000 59.87802  ? 180 ARG   B NH1 1 
ATOM   4767 N  NH2 . ARG   B 2 97  ? 26.88439 29.48921  100.27416 1.000 82.23960  ? 180 ARG   B NH2 1 
ATOM   4768 N  N   . LEU   B 2 98  ? 33.44116 27.03460  96.12355  1.000 66.77971  ? 181 LEU   B N   1 
ATOM   4769 C  CA  . LEU   B 2 98  ? 33.02623 26.52956  94.81666  1.000 63.87220  ? 181 LEU   B CA  1 
ATOM   4770 C  C   . LEU   B 2 98  ? 33.83726 25.30572  94.39818  1.000 69.01567  ? 181 LEU   B C   1 
ATOM   4771 O  O   . LEU   B 2 98  ? 33.29618 24.37297  93.78906  1.000 78.91404  ? 181 LEU   B O   1 
ATOM   4772 C  CB  . LEU   B 2 98  ? 33.14976 27.63034  93.76231  1.000 52.59297  ? 181 LEU   B CB  1 
ATOM   4773 C  CG  . LEU   B 2 98  ? 31.96564 28.58190  93.56809  1.000 59.70046  ? 181 LEU   B CG  1 
ATOM   4774 C  CD1 . LEU   B 2 98  ? 31.67206 29.39313  94.82303  1.000 63.89130  ? 181 LEU   B CD1 1 
ATOM   4775 C  CD2 . LEU   B 2 98  ? 32.22848 29.50068  92.38765  1.000 68.06891  ? 181 LEU   B CD2 1 
ATOM   4776 N  N   . LEU   B 2 99  ? 35.13196 25.29297  94.72229  1.000 67.55341  ? 182 LEU   B N   1 
ATOM   4777 C  CA  . LEU   B 2 99  ? 36.01415 24.22482  94.27158  1.000 67.67627  ? 182 LEU   B CA  1 
ATOM   4778 C  C   . LEU   B 2 99  ? 35.70203 22.90665  94.96312  1.000 63.69960  ? 182 LEU   B C   1 
ATOM   4779 O  O   . LEU   B 2 99  ? 35.85248 21.84251  94.35414  1.000 68.94685  ? 182 LEU   B O   1 
ATOM   4780 C  CB  . LEU   B 2 99  ? 37.47105 24.62344  94.50977  1.000 73.98326  ? 182 LEU   B CB  1 
ATOM   4781 C  CG  . LEU   B 2 99  ? 38.55008 23.84025  93.76210  1.000 83.21977  ? 182 LEU   B CG  1 
ATOM   4782 C  CD1 . LEU   B 2 99  ? 38.33014 23.93385  92.26160  1.000 81.24620  ? 182 LEU   B CD1 1 
ATOM   4783 C  CD2 . LEU   B 2 99  ? 39.92926 24.35873  94.13467  1.000 88.78777  ? 182 LEU   B CD2 1 
ATOM   4784 N  N   . ASN   B 2 100 ? 35.27102 22.95027  96.22557  1.000 65.68827  ? 183 ASN   B N   1 
ATOM   4785 C  CA  . ASN   B 2 100 ? 34.86938 21.71823  96.89945  1.000 71.78663  ? 183 ASN   B CA  1 
ATOM   4786 C  C   . ASN   B 2 100 ? 33.68835 21.06830  96.18565  1.000 68.11551  ? 183 ASN   B C   1 
ATOM   4787 O  O   . ASN   B 2 100 ? 33.69990 19.86195  95.90809  1.000 71.04103  ? 183 ASN   B O   1 
ATOM   4788 C  CB  . ASN   B 2 100 ? 34.53343 22.00089  98.36433  1.000 73.16465  ? 183 ASN   B CB  1 
ATOM   4789 C  CG  . ASN   B 2 100 ? 35.76929 22.24821  99.20813  1.000 68.28219  ? 183 ASN   B CG  1 
ATOM   4790 O  OD1 . ASN   B 2 100 ? 36.41621 21.30847  99.67146  1.000 63.65120  ? 183 ASN   B OD1 1 
ATOM   4791 N  ND2 . ASN   B 2 100 ? 36.10266 23.51701  99.41332  1.000 68.17255  ? 183 ASN   B ND2 1 
ATOM   4792 N  N   . THR   B 2 101 ? 32.66333 21.86307  95.86387  1.000 64.27289  ? 184 THR   B N   1 
ATOM   4793 C  CA  . THR   B 2 101 ? 31.50830 21.33586  95.14300  1.000 64.31919  ? 184 THR   B CA  1 
ATOM   4794 C  C   . THR   B 2 101 ? 31.90433 20.82966  93.76170  1.000 70.98543  ? 184 THR   B C   1 
ATOM   4795 O  O   . THR   B 2 101 ? 31.42695 19.77746  93.31545  1.000 75.03601  ? 184 THR   B O   1 
ATOM   4796 C  CB  . THR   B 2 101 ? 30.42865 22.41109  95.02247  1.000 58.04327  ? 184 THR   B CB  1 
ATOM   4797 O  OG1 . THR   B 2 101 ? 30.86738 23.42729  94.11267  1.000 65.68891  ? 184 THR   B OG1 1 
ATOM   4798 C  CG2 . THR   B 2 101 ? 30.15468 23.04454  96.37712  1.000 56.61418  ? 184 THR   B CG2 1 
ATOM   4799 N  N   . LEU   B 2 102 ? 32.77265 21.56991  93.06695  1.000 67.37476  ? 185 LEU   B N   1 
ATOM   4800 C  CA  . LEU   B 2 102 ? 33.25411 21.11694  91.76543  1.000 64.14101  ? 185 LEU   B CA  1 
ATOM   4801 C  C   . LEU   B 2 102 ? 33.92332 19.75204  91.87398  1.000 73.51510  ? 185 LEU   B C   1 
ATOM   4802 O  O   . LEU   B 2 102 ? 33.55227 18.80868  91.16682  1.000 79.56529  ? 185 LEU   B O   1 
ATOM   4803 C  CB  . LEU   B 2 102 ? 34.21768 22.14558  91.17481  1.000 55.75196  ? 185 LEU   B CB  1 
ATOM   4804 C  CG  . LEU   B 2 102 ? 33.58652 23.42393  90.62529  1.000 59.49720  ? 185 LEU   B CG  1 
ATOM   4805 C  CD1 . LEU   B 2 102 ? 34.66486 24.38885  90.16269  1.000 64.43273  ? 185 LEU   B CD1 1 
ATOM   4806 C  CD2 . LEU   B 2 102 ? 32.63304 23.09242  89.48851  1.000 62.67322  ? 185 LEU   B CD2 1 
ATOM   4807 N  N   . ARG   B 2 103 ? 34.90565 19.62584  92.77125  1.000 74.01020  ? 186 ARG   B N   1 
ATOM   4808 C  CA  . ARG   B 2 103 ? 35.60242 18.35576  92.94754  1.000 72.89863  ? 186 ARG   B CA  1 
ATOM   4809 C  C   . ARG   B 2 103 ? 34.64137 17.24135  93.33760  1.000 74.10209  ? 186 ARG   B C   1 
ATOM   4810 O  O   . ARG   B 2 103 ? 34.84766 16.08308  92.95639  1.000 80.09074  ? 186 ARG   B O   1 
ATOM   4811 C  CB  . ARG   B 2 103 ? 36.70481 18.51148  93.99837  1.000 80.21779  ? 186 ARG   B CB  1 
ATOM   4812 C  CG  . ARG   B 2 103 ? 37.76263 17.41085  94.00201  1.000 90.59079  ? 186 ARG   B CG  1 
ATOM   4813 C  CD  . ARG   B 2 103 ? 37.45608 16.29632  95.00279  1.000 87.68457  ? 186 ARG   B CD  1 
ATOM   4814 N  NE  . ARG   B 2 103 ? 36.30447 16.59405  95.84719  1.000 94.03020  ? 186 ARG   B NE  1 
ATOM   4815 C  CZ  . ARG   B 2 103 ? 36.37612 17.09049  97.07503  1.000 91.24694  ? 186 ARG   B CZ  1 
ATOM   4816 N  NH1 . ARG   B 2 103 ? 37.53904 17.35331  97.64843  1.000 93.58801  ? 186 ARG   B NH1 1 
ATOM   4817 N  NH2 . ARG   B 2 103 ? 35.25163 17.33151  97.74338  1.000 90.04058  ? 186 ARG   B NH2 1 
ATOM   4818 N  N   . GLU   B 2 104 ? 33.58835 17.56748  94.09286  1.000 65.80165  ? 187 GLU   B N   1 
ATOM   4819 C  CA  . GLU   B 2 104 ? 32.59480 16.55576  94.43426  1.000 65.93866  ? 187 GLU   B CA  1 
ATOM   4820 C  C   . GLU   B 2 104 ? 31.79495 16.12598  93.21227  1.000 69.39146  ? 187 GLU   B C   1 
ATOM   4821 O  O   . GLU   B 2 104 ? 31.40117 14.95863  93.10974  1.000 81.76102  ? 187 GLU   B O   1 
ATOM   4822 C  CB  . GLU   B 2 104 ? 31.66209 17.08071  95.52801  1.000 67.55470  ? 187 GLU   B CB  1 
ATOM   4823 C  CG  . GLU   B 2 104 ? 30.84215 16.00383  96.23780  1.000 73.41038  ? 187 GLU   B CG  1 
ATOM   4824 C  CD  . GLU   B 2 104 ? 29.57225 15.62528  95.49282  1.000 80.86289  ? 187 GLU   B CD  1 
ATOM   4825 O  OE1 . GLU   B 2 104 ? 29.13696 16.40080  94.61588  1.000 84.20707  ? 187 GLU   B OE1 1 
ATOM   4826 O  OE2 . GLU   B 2 104 ? 29.00786 14.54992  95.78611  1.000 85.05996  ? 187 GLU   B OE2 1 
ATOM   4827 N  N   . LEU   B 2 105 ? 31.55148 17.04240  92.27844  1.000 66.19613  ? 188 LEU   B N   1 
ATOM   4828 C  CA  . LEU   B 2 105 ? 30.75669 16.72554  91.09807  1.000 74.40611  ? 188 LEU   B CA  1 
ATOM   4829 C  C   . LEU   B 2 105 ? 31.53249 15.99333  90.01010  1.000 74.71333  ? 188 LEU   B C   1 
ATOM   4830 O  O   . LEU   B 2 105 ? 30.97403 15.77368  88.93003  1.000 69.53879  ? 188 LEU   B O   1 
ATOM   4831 C  CB  . LEU   B 2 105 ? 30.15708 18.00317  90.50660  1.000 68.86871  ? 188 LEU   B CB  1 
ATOM   4832 C  CG  . LEU   B 2 105 ? 29.00189 18.63824  91.27511  1.000 69.72923  ? 188 LEU   B CG  1 
ATOM   4833 C  CD1 . LEU   B 2 105 ? 28.43070 19.78432  90.47248  1.000 68.94987  ? 188 LEU   B CD1 1 
ATOM   4834 C  CD2 . LEU   B 2 105 ? 27.92860 17.60636  91.57700  1.000 77.87281  ? 188 LEU   B CD2 1 
ATOM   4835 N  N   . ASN   B 2 106 ? 32.78589 15.61666  90.24656  1.000 75.59950  ? 189 ASN   B N   1 
ATOM   4836 C  CA  . ASN   B 2 106 ? 33.58958 15.03069  89.18564  1.000 78.86518  ? 189 ASN   B CA  1 
ATOM   4837 C  C   . ASN   B 2 106 ? 34.35660 13.81382  89.67992  1.000 83.92521  ? 189 ASN   B C   1 
ATOM   4838 O  O   . ASN   B 2 106 ? 34.65758 13.70088  90.87119  1.000 76.98017  ? 189 ASN   B O   1 
ATOM   4839 C  CB  . ASN   B 2 106 ? 34.59407 16.04241  88.61460  1.000 76.27463  ? 189 ASN   B CB  1 
ATOM   4840 C  CG  . ASN   B 2 106 ? 33.95773 17.36801  88.27573  1.000 75.30492  ? 189 ASN   B CG  1 
ATOM   4841 O  OD1 . ASN   B 2 106 ? 34.45715 18.42118  88.66737  1.000 82.64107  ? 189 ASN   B OD1 1 
ATOM   4842 N  ND2 . ASN   B 2 106 ? 32.85504 17.32900  87.53737  1.000 67.99438  ? 189 ASN   B ND2 1 
ATOM   4843 N  N   . PRO   B 2 107 ? 34.68246 12.88384  88.77772  1.000 91.60011  ? 190 PRO   B N   1 
ATOM   4844 C  CA  . PRO   B 2 107 ? 35.63093 11.82547  89.13966  1.000 89.19240  ? 190 PRO   B CA  1 
ATOM   4845 C  C   . PRO   B 2 107 ? 37.07657 12.26472  89.01272  1.000 95.48312  ? 190 PRO   B C   1 
ATOM   4846 O  O   . PRO   B 2 107 ? 37.95182 11.62835  89.61419  1.000 102.27820 ? 190 PRO   B O   1 
ATOM   4847 C  CB  . PRO   B 2 107 ? 35.29821 10.70788  88.14586  1.000 89.94994  ? 190 PRO   B CB  1 
ATOM   4848 C  CG  . PRO   B 2 107 ? 34.85237 11.45215  86.92412  1.000 84.20244  ? 190 PRO   B CG  1 
ATOM   4849 C  CD  . PRO   B 2 107 ? 34.11972 12.68233  87.42990  1.000 92.33582  ? 190 PRO   B CD  1 
ATOM   4850 N  N   . MET   B 2 108 ? 37.35313 13.33218  88.26600  1.000 95.86394  ? 191 MET   B N   1 
ATOM   4851 C  CA  . MET   B 2 108 ? 38.71652 13.81695  88.13109  1.000 96.39378  ? 191 MET   B CA  1 
ATOM   4852 C  C   . MET   B 2 108 ? 39.21380 14.40068  89.45237  1.000 103.57916 ? 191 MET   B C   1 
ATOM   4853 O  O   . MET   B 2 108 ? 38.43487 14.68468  90.36689  1.000 103.55180 ? 191 MET   B O   1 
ATOM   4854 C  CB  . MET   B 2 108 ? 38.80187 14.86656  87.02462  1.000 90.43524  ? 191 MET   B CB  1 
ATOM   4855 C  CG  . MET   B 2 108 ? 38.03548 16.14838  87.33253  1.000 94.72342  ? 191 MET   B CG  1 
ATOM   4856 S  SD  . MET   B 2 108 ? 38.12971 17.37401  86.01213  1.000 93.65840  ? 191 MET   B SD  1 
ATOM   4857 C  CE  . MET   B 2 108 ? 37.27265 16.52012  84.69097  1.000 83.80109  ? 191 MET   B CE  1 
ATOM   4858 N  N   . TYR   B 2 109 ? 40.53572 14.57507  89.52885  1.000 102.91405 ? 192 TYR   B N   1 
ATOM   4859 C  CA  . TYR   B 2 109 ? 41.27141 15.08499  90.69859  1.000 105.28735 ? 192 TYR   B CA  1 
ATOM   4860 C  C   . TYR   B 2 109 ? 40.44318 15.82618  91.74993  1.000 107.46194 ? 192 TYR   B C   1 
ATOM   4861 O  O   . TYR   B 2 109 ? 39.99084 15.23287  92.72909  1.000 100.18425 ? 192 TYR   B O   1 
ATOM   4862 C  CB  . TYR   B 2 109 ? 42.39838 16.01110  90.22393  1.000 102.52751 ? 192 TYR   B CB  1 
ATOM   4863 C  CG  . TYR   B 2 109 ? 41.94831 17.05005  89.21682  1.000 107.39489 ? 192 TYR   B CG  1 
ATOM   4864 C  CD1 . TYR   B 2 109 ? 41.32260 18.22287  89.62511  1.000 110.88667 ? 192 TYR   B CD1 1 
ATOM   4865 C  CD2 . TYR   B 2 109 ? 42.15413 16.85837  87.85731  1.000 104.26593 ? 192 TYR   B CD2 1 
ATOM   4866 C  CE1 . TYR   B 2 109 ? 40.91017 19.17005  88.70587  1.000 107.14847 ? 192 TYR   B CE1 1 
ATOM   4867 C  CE2 . TYR   B 2 109 ? 41.74673 17.79872  86.93249  1.000 105.91797 ? 192 TYR   B CE2 1 
ATOM   4868 C  CZ  . TYR   B 2 109 ? 41.12535 18.95289  87.36149  1.000 106.12000 ? 192 TYR   B CZ  1 
ATOM   4869 O  OH  . TYR   B 2 109 ? 40.71617 19.89538  86.44605  1.000 95.53193  ? 192 TYR   B OH  1 
ATOM   4870 N  N   . LEU   B 2 113 ? 47.91148 21.14337  93.66870  1.000 98.62246  ? 196 LEU   B N   1 
ATOM   4871 C  CA  . LEU   B 2 113 ? 47.36683 22.44122  94.04972  1.000 108.10509 ? 196 LEU   B CA  1 
ATOM   4872 C  C   . LEU   B 2 113 ? 47.09939 23.29709  92.81438  1.000 106.82242 ? 196 LEU   B C   1 
ATOM   4873 O  O   . LEU   B 2 113 ? 46.51118 24.37493  92.90644  1.000 100.17073 ? 196 LEU   B O   1 
ATOM   4874 C  CB  . LEU   B 2 113 ? 48.32181 23.16390  95.00245  1.000 105.60620 ? 196 LEU   B CB  1 
ATOM   4875 C  CG  . LEU   B 2 113 ? 48.78808 22.36445  96.22255  1.000 100.10768 ? 196 LEU   B CG  1 
ATOM   4876 C  CD1 . LEU   B 2 113 ? 49.69713 23.20656  97.10644  1.000 86.53961  ? 196 LEU   B CD1 1 
ATOM   4877 C  CD2 . LEU   B 2 113 ? 47.60136 21.83430  97.01514  1.000 88.99652  ? 196 LEU   B CD2 1 
ATOM   4878 N  N   . GLN   B 2 114 ? 47.54026 22.80433  91.65814  1.000 108.27879 ? 197 GLN   B N   1 
ATOM   4879 C  CA  . GLN   B 2 114 ? 47.33877 23.47446  90.38168  1.000 106.78558 ? 197 GLN   B CA  1 
ATOM   4880 C  C   . GLN   B 2 114 ? 46.92135 22.44443  89.34397  1.000 102.51703 ? 197 GLN   B C   1 
ATOM   4881 O  O   . GLN   B 2 114 ? 47.42817 21.31913  89.34030  1.000 100.80790 ? 197 GLN   B O   1 
ATOM   4882 C  CB  . GLN   B 2 114 ? 48.61133 24.19637  89.91457  1.000 112.79977 ? 197 GLN   B CB  1 
ATOM   4883 C  CG  . GLN   B 2 114 ? 49.06153 25.34438  90.80668  1.000 115.44598 ? 197 GLN   B CG  1 
ATOM   4884 C  CD  . GLN   B 2 114 ? 48.55503 26.69236  90.32923  1.000 112.22728 ? 197 GLN   B CD  1 
ATOM   4885 O  OE1 . GLN   B 2 114 ? 47.55902 26.77669  89.61070  1.000 107.87136 ? 197 GLN   B OE1 1 
ATOM   4886 N  NE2 . GLN   B 2 114 ? 49.24777 27.75624  90.72064  1.000 103.78576 ? 197 GLN   B NE2 1 
ATOM   4887 N  N   . HIS   B 2 115 ? 46.00069 22.83149  88.46601  1.000 97.30369  ? 198 HIS   B N   1 
ATOM   4888 C  CA  . HIS   B 2 115 ? 45.52798 21.94410  87.41079  1.000 97.19051  ? 198 HIS   B CA  1 
ATOM   4889 C  C   . HIS   B 2 115 ? 45.17938 22.78186  86.18538  1.000 96.39334  ? 198 HIS   B C   1 
ATOM   4890 O  O   . HIS   B 2 115 ? 45.50554 23.97040  86.10822  1.000 95.33944  ? 198 HIS   B O   1 
ATOM   4891 C  CB  . HIS   B 2 115 ? 44.33894 21.10335  87.89331  1.000 95.68793  ? 198 HIS   B CB  1 
ATOM   4892 C  CG  . HIS   B 2 115 ? 44.73118 19.93610  88.74425  1.000 95.67897  ? 198 HIS   B CG  1 
ATOM   4893 N  ND1 . HIS   B 2 115 ? 44.64303 19.95325  90.11952  1.000 95.45006  ? 198 HIS   B ND1 1 
ATOM   4894 C  CD2 . HIS   B 2 115 ? 45.21998 18.71729  88.41389  1.000 93.56627  ? 198 HIS   B CD2 1 
ATOM   4895 C  CE1 . HIS   B 2 115 ? 45.05612 18.79381  90.59954  1.000 93.01466  ? 198 HIS   B CE1 1 
ATOM   4896 N  NE2 . HIS   B 2 115 ? 45.41227 18.02616  89.58540  1.000 94.16261  ? 198 HIS   B NE2 1 
ATOM   4897 N  N   . ASP   B 2 116 ? 44.51056 22.15101  85.22357  1.000 93.20919  ? 199 ASP   B N   1 
ATOM   4898 C  CA  . ASP   B 2 116 ? 44.18478 22.81029  83.96713  1.000 89.11546  ? 199 ASP   B CA  1 
ATOM   4899 C  C   . ASP   B 2 116 ? 43.11508 23.87499  84.17645  1.000 83.04753  ? 199 ASP   B C   1 
ATOM   4900 O  O   . ASP   B 2 116 ? 42.11004 23.64624  84.85497  1.000 86.07045  ? 199 ASP   B O   1 
ATOM   4901 C  CB  . ASP   B 2 116 ? 43.70626 21.77885  82.94352  1.000 85.30907  ? 199 ASP   B CB  1 
ATOM   4902 C  CG  . ASP   B 2 116 ? 43.76226 22.29396  81.51541  1.000 86.61241  ? 199 ASP   B CG  1 
ATOM   4903 O  OD1 . ASP   B 2 116 ? 43.68423 23.52341  81.31028  1.000 93.04479  ? 199 ASP   B OD1 1 
ATOM   4904 O  OD2 . ASP   B 2 116 ? 43.88313 21.46133  80.59190  1.000 72.86183  ? 199 ASP   B OD2 1 
ATOM   4905 N  N   . ALA   B 2 117 ? 43.33820 25.04898  83.58134  1.000 78.89380  ? 200 ALA   B N   1 
ATOM   4906 C  CA  . ALA   B 2 117 ? 42.34187 26.11225  83.61028  1.000 84.02647  ? 200 ALA   B CA  1 
ATOM   4907 C  C   . ALA   B 2 117 ? 41.27000 25.94295  82.54403  1.000 83.85844  ? 200 ALA   B C   1 
ATOM   4908 O  O   . ALA   B 2 117 ? 40.21602 26.57997  82.63951  1.000 81.08804  ? 200 ALA   B O   1 
ATOM   4909 C  CB  . ALA   B 2 117 ? 43.01194 27.47760  83.44534  1.000 83.10501  ? 200 ALA   B CB  1 
ATOM   4910 N  N   . GLN   B 2 118 ? 41.51671 25.11725  81.52736  1.000 84.98490  ? 201 GLN   B N   1 
ATOM   4911 C  CA  . GLN   B 2 118 ? 40.48240 24.84727  80.53585  1.000 79.86557  ? 201 GLN   B CA  1 
ATOM   4912 C  C   . GLN   B 2 118 ? 39.55317 23.73305  80.99806  1.000 75.75707  ? 201 GLN   B C   1 
ATOM   4913 O  O   . GLN   B 2 118 ? 38.34360 23.78366  80.74379  1.000 75.33402  ? 201 GLN   B O   1 
ATOM   4914 C  CB  . GLN   B 2 118 ? 41.12334 24.50327  79.18903  1.000 81.72139  ? 201 GLN   B CB  1 
ATOM   4915 C  CG  . GLN   B 2 118 ? 40.13632 24.16152  78.08424  1.000 79.66489  ? 201 GLN   B CG  1 
ATOM   4916 C  CD  . GLN   B 2 118 ? 39.78857 22.68801  78.05384  1.000 84.62106  ? 201 GLN   B CD  1 
ATOM   4917 O  OE1 . GLN   B 2 118 ? 38.62656 22.30711  78.19706  1.000 91.29474  ? 201 GLN   B OE1 1 
ATOM   4918 N  NE2 . GLN   B 2 118 ? 40.80002 21.84842  77.87379  1.000 81.44163  ? 201 GLN   B NE2 1 
ATOM   4919 N  N   . GLU   B 2 119 ? 40.10235 22.72850  81.68424  1.000 75.77599  ? 202 GLU   B N   1 
ATOM   4920 C  CA  . GLU   B 2 119 ? 39.27796 21.63681  82.19114  1.000 76.76211  ? 202 GLU   B CA  1 
ATOM   4921 C  C   . GLU   B 2 119 ? 38.25503 22.14147  83.20257  1.000 67.64087  ? 202 GLU   B C   1 
ATOM   4922 O  O   . GLU   B 2 119 ? 37.09227 21.71822  83.18744  1.000 65.28664  ? 202 GLU   B O   1 
ATOM   4923 C  CB  . GLU   B 2 119 ? 40.16593 20.56158  82.81826  1.000 82.43743  ? 202 GLU   B CB  1 
ATOM   4924 C  CG  . GLU   B 2 119 ? 39.47898 19.22610  83.04365  1.000 85.31605  ? 202 GLU   B CG  1 
ATOM   4925 C  CD  . GLU   B 2 119 ? 39.28866 18.44341  81.75893  1.000 90.08782  ? 202 GLU   B CD  1 
ATOM   4926 O  OE1 . GLU   B 2 119 ? 39.92628 18.79372  80.74321  1.000 87.95175  ? 202 GLU   B OE1 1 
ATOM   4927 O  OE2 . GLU   B 2 119 ? 38.49958 17.47538  81.76537  1.000 94.86710  ? 202 GLU   B OE2 1 
ATOM   4928 N  N   . VAL   B 2 120 ? 38.66604 23.05728  84.08350  1.000 65.39505  ? 203 VAL   B N   1 
ATOM   4929 C  CA  . VAL   B 2 120 ? 37.73762 23.59465  85.07279  1.000 67.51297  ? 203 VAL   B CA  1 
ATOM   4930 C  C   . VAL   B 2 120 ? 36.67027 24.45375  84.40371  1.000 64.47272  ? 203 VAL   B C   1 
ATOM   4931 O  O   . VAL   B 2 120 ? 35.51668 24.47368  84.84662  1.000 66.43060  ? 203 VAL   B O   1 
ATOM   4932 C  CB  . VAL   B 2 120 ? 38.50380 24.37288  86.16185  1.000 70.85167  ? 203 VAL   B CB  1 
ATOM   4933 C  CG1 . VAL   B 2 120 ? 39.26414 25.54687  85.56182  1.000 69.27074  ? 203 VAL   B CG1 1 
ATOM   4934 C  CG2 . VAL   B 2 120 ? 37.55509 24.84253  87.25632  1.000 61.02849  ? 203 VAL   B CG2 1 
ATOM   4935 N  N   . LEU   B 2 121 ? 37.01857 25.15477  83.32169  1.000 63.72898  ? 204 LEU   B N   1 
ATOM   4936 C  CA  . LEU   B 2 121 ? 36.02807 25.95468  82.60620  1.000 62.67963  ? 204 LEU   B CA  1 
ATOM   4937 C  C   . LEU   B 2 121 ? 34.94527 25.06956  82.00215  1.000 64.71936  ? 204 LEU   B C   1 
ATOM   4938 O  O   . LEU   B 2 121 ? 33.74488 25.30234  82.20593  1.000 62.20173  ? 204 LEU   B O   1 
ATOM   4939 C  CB  . LEU   B 2 121 ? 36.71078 26.78158  81.51675  1.000 61.97868  ? 204 LEU   B CB  1 
ATOM   4940 C  CG  . LEU   B 2 121 ? 35.77584 27.59118  80.61556  1.000 63.02785  ? 204 LEU   B CG  1 
ATOM   4941 C  CD1 . LEU   B 2 121 ? 35.25954 28.82522  81.34216  1.000 63.24937  ? 204 LEU   B CD1 1 
ATOM   4942 C  CD2 . LEU   B 2 121 ? 36.46518 27.97064  79.31366  1.000 65.70410  ? 204 LEU   B CD2 1 
ATOM   4943 N  N   . GLN   B 2 122 ? 35.35747 24.05288  81.23949  1.000 71.80734  ? 205 GLN   B N   1 
ATOM   4944 C  CA  . GLN   B 2 122 ? 34.39774 23.11828  80.66500  1.000 70.85921  ? 205 GLN   B CA  1 
ATOM   4945 C  C   . GLN   B 2 122 ? 33.59847 22.41823  81.75311  1.000 63.20029  ? 205 GLN   B C   1 
ATOM   4946 O  O   . GLN   B 2 122 ? 32.40558 22.15322  81.58061  1.000 64.26533  ? 205 GLN   B O   1 
ATOM   4947 C  CB  . GLN   B 2 122 ? 35.11657 22.09295  79.78783  1.000 73.30825  ? 205 GLN   B CB  1 
ATOM   4948 C  CG  . GLN   B 2 122 ? 34.76986 22.18662  78.31084  1.000 80.88598  ? 205 GLN   B CG  1 
ATOM   4949 C  CD  . GLN   B 2 122 ? 35.17153 20.94485  77.53825  1.000 91.80605  ? 205 GLN   B CD  1 
ATOM   4950 O  OE1 . GLN   B 2 122 ? 35.78049 20.02698  78.08841  1.000 94.76006  ? 205 GLN   B OE1 1 
ATOM   4951 N  NE2 . GLN   B 2 122 ? 34.82575 20.90771  76.25627  1.000 88.04149  ? 205 GLN   B NE2 1 
ATOM   4952 N  N   . CYS   B 2 123 ? 34.23135 22.13324  82.89276  1.000 58.82383  ? 206 CYS   B N   1 
ATOM   4953 C  CA  . CYS   B 2 123 ? 33.52933 21.44070  83.96704  1.000 58.53273  ? 206 CYS   B CA  1 
ATOM   4954 C  C   . CYS   B 2 123 ? 32.45292 22.32312  84.58743  1.000 58.95307  ? 206 CYS   B C   1 
ATOM   4955 O  O   . CYS   B 2 123 ? 31.33332 21.86209  84.83831  1.000 62.01645  ? 206 CYS   B O   1 
ATOM   4956 C  CB  . CYS   B 2 123 ? 34.52587 20.98069  85.02684  1.000 59.06491  ? 206 CYS   B CB  1 
ATOM   4957 S  SG  . CYS   B 2 123 ? 34.12811 19.37613  85.72350  1.000 68.55447  ? 206 CYS   B SG  1 
ATOM   4958 N  N   . ILE   B 2 124 ? 32.77249 23.59350  84.84197  1.000 62.28207  ? 207 ILE   B N   1 
ATOM   4959 C  CA  . ILE   B 2 124 ? 31.78162 24.51798  85.38503  1.000 67.41497  ? 207 ILE   B CA  1 
ATOM   4960 C  C   . ILE   B 2 124 ? 30.63567 24.70554  84.40080  1.000 64.96196  ? 207 ILE   B C   1 
ATOM   4961 O  O   . ILE   B 2 124 ? 29.45804 24.68783  84.78433  1.000 67.15443  ? 207 ILE   B O   1 
ATOM   4962 C  CB  . ILE   B 2 124 ? 32.44450 25.86038  85.74692  1.000 61.81980  ? 207 ILE   B CB  1 
ATOM   4963 C  CG1 . ILE   B 2 124 ? 33.41795 25.67690  86.91229  1.000 61.80314  ? 207 ILE   B CG1 1 
ATOM   4964 C  CG2 . ILE   B 2 124 ? 31.39208 26.90640  86.08662  1.000 49.33186  ? 207 ILE   B CG2 1 
ATOM   4965 C  CD1 . ILE   B 2 124 ? 34.12618 26.94700  87.31927  1.000 53.99501  ? 207 ILE   B CD1 1 
ATOM   4966 N  N   . LEU   B 2 125 ? 30.95861 24.88238  83.11611  1.000 61.02804  ? 208 LEU   B N   1 
ATOM   4967 C  CA  . LEU   B 2 125 ? 29.90905 25.05627  82.11660  1.000 66.96185  ? 208 LEU   B CA  1 
ATOM   4968 C  C   . LEU   B 2 125 ? 29.02815 23.81541  82.01913  1.000 71.57649  ? 208 LEU   B C   1 
ATOM   4969 O  O   . LEU   B 2 125 ? 27.80048 23.92209  81.90337  1.000 77.93080  ? 208 LEU   B O   1 
ATOM   4970 C  CB  . LEU   B 2 125 ? 30.52899 25.39251  80.76074  1.000 73.48317  ? 208 LEU   B CB  1 
ATOM   4971 C  CG  . LEU   B 2 125 ? 31.26149 26.73442  80.68497  1.000 69.51359  ? 208 LEU   B CG  1 
ATOM   4972 C  CD1 . LEU   B 2 125 ? 31.86240 26.94699  79.30426  1.000 71.98847  ? 208 LEU   B CD1 1 
ATOM   4973 C  CD2 . LEU   B 2 125 ? 30.32655 27.87793  81.04917  1.000 63.54393  ? 208 LEU   B CD2 1 
ATOM   4974 N  N   . GLY   B 2 126 ? 29.63381 22.62848  82.08955  1.000 66.90390  ? 209 GLY   B N   1 
ATOM   4975 C  CA  . GLY   B 2 126 ? 28.85500 21.40524  82.02588  1.000 69.96484  ? 209 GLY   B CA  1 
ATOM   4976 C  C   . GLY   B 2 126 ? 27.98090 21.20415  83.24714  1.000 75.30320  ? 209 GLY   B C   1 
ATOM   4977 O  O   . GLY   B 2 126 ? 26.85917 20.70912  83.13806  1.000 83.92113  ? 209 GLY   B O   1 
ATOM   4978 N  N   . ASN   B 2 127 ? 28.47358 21.59343  84.42548  1.000 72.35028  ? 210 ASN   B N   1 
ATOM   4979 C  CA  . ASN   B 2 127 ? 27.65295 21.49287  85.62903  1.000 71.28606  ? 210 ASN   B CA  1 
ATOM   4980 C  C   . ASN   B 2 127 ? 26.48541 22.47274  85.58309  1.000 70.90884  ? 210 ASN   B C   1 
ATOM   4981 O  O   . ASN   B 2 127 ? 25.37041 22.14364  86.01339  1.000 75.61427  ? 210 ASN   B O   1 
ATOM   4982 C  CB  . ASN   B 2 127 ? 28.51189 21.72749  86.87185  1.000 68.84852  ? 210 ASN   B CB  1 
ATOM   4983 C  CG  . ASN   B 2 127 ? 29.52860 20.62256  87.09538  1.000 69.24248  ? 210 ASN   B CG  1 
ATOM   4984 O  OD1 . ASN   B 2 127 ? 29.25651 19.45022  86.83586  1.000 77.38203  ? 210 ASN   B OD1 1 
ATOM   4985 N  ND2 . ASN   B 2 127 ? 30.70868 20.99310  87.57835  1.000 65.60094  ? 210 ASN   B ND2 1 
ATOM   4986 N  N   . ILE   B 2 128 ? 26.71709 23.67803  85.05511  1.000 68.96440  ? 211 ILE   B N   1 
ATOM   4987 C  CA  . ILE   B 2 128 ? 25.62575 24.63934  84.91748  1.000 73.17649  ? 211 ILE   B CA  1 
ATOM   4988 C  C   . ILE   B 2 128 ? 24.59582 24.13094  83.91628  1.000 76.04852  ? 211 ILE   B C   1 
ATOM   4989 O  O   . ILE   B 2 128 ? 23.38579 24.25716  84.13057  1.000 77.69254  ? 211 ILE   B O   1 
ATOM   4990 C  CB  . ILE   B 2 128 ? 26.17006 26.02539  84.52442  1.000 69.10907  ? 211 ILE   B CB  1 
ATOM   4991 C  CG1 . ILE   B 2 128 ? 27.08758 26.56661  85.62172  1.000 64.38121  ? 211 ILE   B CG1 1 
ATOM   4992 C  CG2 . ILE   B 2 128 ? 25.02795 26.99781  84.28216  1.000 62.14459  ? 211 ILE   B CG2 1 
ATOM   4993 C  CD1 . ILE   B 2 128 ? 27.72590 27.89539  85.28557  1.000 62.37291  ? 211 ILE   B CD1 1 
ATOM   4994 N  N   . GLN   B 2 129 ? 25.05454 23.52967  82.81651  1.000 74.99287  ? 212 GLN   B N   1 
ATOM   4995 C  CA  . GLN   B 2 129 ? 24.11911 22.93615  81.86490  1.000 80.09018  ? 212 GLN   B CA  1 
ATOM   4996 C  C   . GLN   B 2 129 ? 23.36957 21.75550  82.47661  1.000 81.84780  ? 212 GLN   B C   1 
ATOM   4997 O  O   . GLN   B 2 129 ? 22.18350 21.55481  82.18695  1.000 84.76936  ? 212 GLN   B O   1 
ATOM   4998 C  CB  . GLN   B 2 129 ? 24.86768 22.50930  80.60151  1.000 82.28421  ? 212 GLN   B CB  1 
ATOM   4999 C  CG  . GLN   B 2 129 ? 23.98212 22.07627  79.44935  1.000 87.37751  ? 212 GLN   B CG  1 
ATOM   5000 C  CD  . GLN   B 2 129 ? 24.73713 22.01733  78.13433  1.000 99.51600  ? 212 GLN   B CD  1 
ATOM   5001 O  OE1 . GLN   B 2 129 ? 25.62689 22.83018  77.87624  1.000 99.35113  ? 212 GLN   B OE1 1 
ATOM   5002 N  NE2 . GLN   B 2 129 ? 24.39004 21.04780  77.29804  1.000 103.98373 ? 212 GLN   B NE2 1 
ATOM   5003 N  N   . GLU   B 2 130 ? 24.03709 20.98033  83.33416  1.000 79.56189  ? 213 GLU   B N   1 
ATOM   5004 C  CA  . GLU   B 2 130 ? 23.38956 19.85731  84.00241  1.000 79.98974  ? 213 GLU   B CA  1 
ATOM   5005 C  C   . GLU   B 2 130 ? 22.26702 20.33979  84.91054  1.000 81.43414  ? 213 GLU   B C   1 
ATOM   5006 O  O   . GLU   B 2 130 ? 21.15366 19.80164  84.88312  1.000 86.77755  ? 213 GLU   B O   1 
ATOM   5007 C  CB  . GLU   B 2 130 ? 24.42649 19.06382  84.80033  1.000 79.48395  ? 213 GLU   B CB  1 
ATOM   5008 C  CG  . GLU   B 2 130 ? 24.03123 17.62743  85.09897  1.000 87.74132  ? 213 GLU   B CG  1 
ATOM   5009 C  CD  . GLU   B 2 130 ? 24.40207 16.67925  83.97355  1.000 105.97977 ? 213 GLU   B CD  1 
ATOM   5010 O  OE1 . GLU   B 2 130 ? 24.87757 17.16092  82.92356  1.000 96.23928  ? 213 GLU   B OE1 1 
ATOM   5011 O  OE2 . GLU   B 2 130 ? 24.22676 15.45318  84.13952  1.000 117.22971 ? 213 GLU   B OE2 1 
ATOM   5012 N  N   . THR   B 2 131 ? 22.54101 21.36171  85.72632  1.000 81.31309  ? 214 THR   B N   1 
ATOM   5013 C  CA  . THR   B 2 131 ? 21.48620 21.88327  86.59074  1.000 86.56792  ? 214 THR   B CA  1 
ATOM   5014 C  C   . THR   B 2 131 ? 20.41046 22.60261  85.78214  1.000 87.36205  ? 214 THR   B C   1 
ATOM   5015 O  O   . THR   B 2 131 ? 19.24344 22.62202  86.18984  1.000 89.33352  ? 214 THR   B O   1 
ATOM   5016 C  CB  . THR   B 2 131 ? 22.06889 22.79760  87.67467  1.000 83.23581  ? 214 THR   B CB  1 
ATOM   5017 O  OG1 . THR   B 2 131 ? 21.04666 23.12429  88.62486  1.000 85.52571  ? 214 THR   B OG1 1 
ATOM   5018 C  CG2 . THR   B 2 131 ? 22.61981 24.08085  87.08486  1.000 80.22985  ? 214 THR   B CG2 1 
ATOM   5019 N  N   . CYS   B 2 132 ? 20.76666 23.15570  84.61787  1.000 85.39660  ? 215 CYS   B N   1 
ATOM   5020 C  CA  . CYS   B 2 132 ? 19.75424 23.71314  83.72695  1.000 85.28744  ? 215 CYS   B CA  1 
ATOM   5021 C  C   . CYS   B 2 132 ? 18.79902 22.63278  83.24007  1.000 88.87131  ? 215 CYS   B C   1 
ATOM   5022 O  O   . CYS   B 2 132 ? 17.58214 22.83857  83.21190  1.000 94.19269  ? 215 CYS   B O   1 
ATOM   5023 C  CB  . CYS   B 2 132 ? 20.41825 24.41197  82.53998  1.000 86.22166  ? 215 CYS   B CB  1 
ATOM   5024 S  SG  . CYS   B 2 132 ? 21.12811 26.03058  82.91510  1.000 94.40731  ? 215 CYS   B SG  1 
ATOM   5025 N  N   . GLN   B 2 133 ? 19.33314 21.47309  82.85162  1.000 86.35968  ? 216 GLN   B N   1 
ATOM   5026 C  CA  . GLN   B 2 133 ? 18.47169 20.36226  82.45113  1.000 89.80965  ? 216 GLN   B CA  1 
ATOM   5027 C  C   . GLN   B 2 133 ? 17.63912 19.85784  83.62508  1.000 88.52162  ? 216 GLN   B C   1 
ATOM   5028 O  O   . GLN   B 2 133 ? 16.45688 19.52275  83.46369  1.000 90.51909  ? 216 GLN   B O   1 
ATOM   5029 C  CB  . GLN   B 2 133 ? 19.31346 19.22760  81.86943  1.000 92.62833  ? 216 GLN   B CB  1 
ATOM   5030 C  CG  . GLN   B 2 133 ? 20.14985 19.62497  80.66804  1.000 92.65156  ? 216 GLN   B CG  1 
ATOM   5031 C  CD  . GLN   B 2 133 ? 21.11068 18.53290  80.24467  1.000 99.21186  ? 216 GLN   B CD  1 
ATOM   5032 O  OE1 . GLN   B 2 133 ? 20.90218 17.35659  80.54198  1.000 101.64120 ? 216 GLN   B OE1 1 
ATOM   5033 N  NE2 . GLN   B 2 133 ? 22.17623 18.91856  79.55281  1.000 102.41206 ? 216 GLN   B NE2 1 
ATOM   5034 N  N   . LEU   B 2 134 ? 18.24480 19.79348  84.81298  1.000 87.06446  ? 217 LEU   B N   1 
ATOM   5035 C  CA  . LEU   B 2 134 ? 17.53118 19.31799  85.99393  1.000 87.26551  ? 217 LEU   B CA  1 
ATOM   5036 C  C   . LEU   B 2 134 ? 16.39245 20.25452  86.37854  1.000 85.67935  ? 217 LEU   B C   1 
ATOM   5037 O  O   . LEU   B 2 134 ? 15.37783 19.80385  86.92236  1.000 87.98618  ? 217 LEU   B O   1 
ATOM   5038 C  CB  . LEU   B 2 134 ? 18.50564 19.15172  87.16125  1.000 84.30867  ? 217 LEU   B CB  1 
ATOM   5039 C  CG  . LEU   B 2 134 ? 19.25520 17.82344  87.32487  1.000 80.45166  ? 217 LEU   B CG  1 
ATOM   5040 C  CD1 . LEU   B 2 134 ? 19.56864 17.15925  85.98960  1.000 73.48277  ? 217 LEU   B CD1 1 
ATOM   5041 C  CD2 . LEU   B 2 134 ? 20.53618 18.05037  88.11219  1.000 80.51122  ? 217 LEU   B CD2 1 
ATOM   5042 N  N   . LEU   B 2 135 ? 16.54231 21.55347  86.11279  1.000 86.45482  ? 218 LEU   B N   1 
ATOM   5043 C  CA  . LEU   B 2 135 ? 15.45129 22.49206  86.35024  1.000 90.59047  ? 218 LEU   B CA  1 
ATOM   5044 C  C   . LEU   B 2 135 ? 14.44809 22.50422  85.20137  1.000 96.23649  ? 218 LEU   B C   1 
ATOM   5045 O  O   . LEU   B 2 135 ? 13.26465 22.78584  85.42201  1.000 93.71356  ? 218 LEU   B O   1 
ATOM   5046 C  CB  . LEU   B 2 135 ? 16.00951 23.89646  86.58310  1.000 86.10221  ? 218 LEU   B CB  1 
ATOM   5047 C  CG  . LEU   B 2 135 ? 16.83582 24.10717  87.85357  1.000 78.64873  ? 218 LEU   B CG  1 
ATOM   5048 C  CD1 . LEU   B 2 135 ? 17.49777 25.47545  87.84110  1.000 74.70005  ? 218 LEU   B CD1 1 
ATOM   5049 C  CD2 . LEU   B 2 135 ? 15.96763 23.94385  89.09099  1.000 83.11576  ? 218 LEU   B CD2 1 
ATOM   5050 N  N   . LYS   B 2 136 ? 14.90006 22.21330  83.97769  1.000 101.02037 ? 219 LYS   B N   1 
ATOM   5051 C  CA  . LYS   B 2 136 ? 13.97990 22.06662  82.85413  1.000 102.91101 ? 219 LYS   B CA  1 
ATOM   5052 C  C   . LYS   B 2 136 ? 13.01602 20.91448  83.08590  1.000 100.48480 ? 219 LYS   B C   1 
ATOM   5053 O  O   . LYS   B 2 136 ? 11.81799 21.02579  82.79993  1.000 101.65445 ? 219 LYS   B O   1 
ATOM   5054 C  CB  . LYS   B 2 136 ? 14.75958 21.84067  81.55787  1.000 107.76228 ? 219 LYS   B CB  1 
ATOM   5055 C  CG  . LYS   B 2 136 ? 14.94783 23.07799  80.70559  1.000 113.66351 ? 219 LYS   B CG  1 
ATOM   5056 C  CD  . LYS   B 2 136 ? 15.64549 22.74786  79.39388  1.000 119.85415 ? 219 LYS   B CD  1 
ATOM   5057 C  CE  . LYS   B 2 136 ? 17.03116 22.16895  79.62968  1.000 110.10587 ? 219 LYS   B CE  1 
ATOM   5058 N  NZ  . LYS   B 2 136 ? 17.72334 21.83938  78.35282  1.000 106.84956 ? 219 LYS   B NZ  1 
ATOM   5059 N  N   . LYS   B 2 137 ? 13.52340 19.79801  83.60509  1.000 101.29646 ? 220 LYS   B N   1 
ATOM   5060 C  CA  . LYS   B 2 137 ? 12.68939 18.62568  83.84697  1.000 102.66317 ? 220 LYS   B CA  1 
ATOM   5061 C  C   . LYS   B 2 137 ? 11.64076 18.84440  84.93402  1.000 100.59419 ? 220 LYS   B C   1 
ATOM   5062 O  O   . LYS   B 2 137 ? 10.87046 17.91876  85.21300  1.000 101.47902 ? 220 LYS   B O   1 
ATOM   5063 C  CB  . LYS   B 2 137 ? 13.57353 17.42990  84.20261  1.000 99.30586  ? 220 LYS   B CB  1 
ATOM   5064 C  CG  . LYS   B 2 137 ? 14.49677 17.00716  83.07214  1.000 94.35658  ? 220 LYS   B CG  1 
ATOM   5065 C  CD  . LYS   B 2 137 ? 15.67471 16.19866  83.58242  1.000 92.53076  ? 220 LYS   B CD  1 
ATOM   5066 C  CE  . LYS   B 2 137 ? 16.67968 15.94396  82.47145  1.000 88.82344  ? 220 LYS   B CE  1 
ATOM   5067 N  NZ  . LYS   B 2 137 ? 17.91316 15.28280  82.97694  1.000 80.23789  ? 220 LYS   B NZ  1 
ATOM   5068 N  N   . GLU   B 2 138 ? 11.58546 20.03015  85.55091  1.000 95.16770  ? 221 GLU   B N   1 
ATOM   5069 C  CA  . GLU   B 2 138 ? 10.57770 20.33780  86.55999  1.000 100.12320 ? 221 GLU   B CA  1 
ATOM   5070 C  C   . GLU   B 2 138 ? 9.89315  21.67489  86.29174  1.000 110.53492 ? 221 GLU   B C   1 
ATOM   5071 O  O   . GLU   B 2 138 ? 9.33660  22.27618  87.21637  1.000 107.73755 ? 221 GLU   B O   1 
ATOM   5072 C  CB  . GLU   B 2 138 ? 11.19244 20.33288  87.96261  1.000 99.20013  ? 221 GLU   B CB  1 
ATOM   5073 C  CG  . GLU   B 2 138 ? 11.89501 19.03512  88.32891  1.000 102.94781 ? 221 GLU   B CG  1 
ATOM   5074 C  CD  . GLU   B 2 138 ? 12.37330 19.01424  89.76639  1.000 119.30800 ? 221 GLU   B CD  1 
ATOM   5075 O  OE1 . GLU   B 2 138 ? 11.68646 19.59663  90.63169  1.000 125.21197 ? 221 GLU   B OE1 1 
ATOM   5076 O  OE2 . GLU   B 2 138 ? 13.43886 18.41877  90.03063  1.000 121.85434 ? 221 GLU   B OE2 1 
ATOM   5077 N  N   . GLU   B 2 139 ? 9.92628  22.15559  85.04786  1.000 117.80046 ? 222 GLU   B N   1 
ATOM   5078 C  CA  . GLU   B 2 139 ? 9.26470  23.40051  84.66730  1.000 121.02665 ? 222 GLU   B CA  1 
ATOM   5079 C  C   . GLU   B 2 139 ? 7.97621  23.13792  83.89330  1.000 123.97385 ? 222 GLU   B C   1 
ATOM   5080 O  O   . GLU   B 2 139 ? 6.89920  23.58310  84.30138  1.000 120.54801 ? 222 GLU   B O   1 
ATOM   5081 C  CB  . GLU   B 2 139 ? 10.22164 24.27319  83.84228  1.000 116.02601 ? 222 GLU   B CB  1 
ATOM   5082 C  CG  . GLU   B 2 139 ? 9.61662  25.58055  83.34162  1.000 122.79790 ? 222 GLU   B CG  1 
ATOM   5083 C  CD  . GLU   B 2 139 ? 9.55348  26.65580  84.41300  1.000 123.63728 ? 222 GLU   B CD  1 
ATOM   5084 O  OE1 . GLU   B 2 139 ? 9.91867  26.37003  85.57280  1.000 121.89623 ? 222 GLU   B OE1 1 
ATOM   5085 O  OE2 . GLU   B 2 139 ? 9.14404  27.79229  84.09203  1.000 118.87990 ? 222 GLU   B OE2 1 
ATOM   5086 N  N   . GLY   B 2 140 ? 8.07118  22.41725  82.77480  1.000 124.46040 ? 223 GLY   B N   1 
ATOM   5087 C  CA  . GLY   B 2 140 ? 6.89389  22.02588  82.02321  1.000 123.99023 ? 223 GLY   B CA  1 
ATOM   5088 C  C   . GLY   B 2 140 ? 6.16313  20.81782  82.56456  1.000 135.93133 ? 223 GLY   B C   1 
ATOM   5089 O  O   . GLY   B 2 140 ? 5.06681  20.50707  82.08846  1.000 141.34638 ? 223 GLY   B O   1 
ATOM   5090 N  N   . SER   B 2 141 ? 6.74466  20.12923  83.54709  1.000 136.44549 ? 224 SER   B N   1 
ATOM   5091 C  CA  . SER   B 2 141 ? 6.12661  18.97106  84.17954  1.000 133.49205 ? 224 SER   B CA  1 
ATOM   5092 C  C   . SER   B 2 141 ? 5.76432  19.24796  85.63601  1.000 127.70579 ? 224 SER   B C   1 
ATOM   5093 O  O   . SER   B 2 141 ? 5.82490  18.35013  86.47928  1.000 123.81246 ? 224 SER   B O   1 
ATOM   5094 C  CB  . SER   B 2 141 ? 7.04573  17.75465  84.08164  1.000 132.79033 ? 224 SER   B CB  1 
ATOM   5095 O  OG  . SER   B 2 141 ? 7.32599  17.43317  82.73038  1.000 143.49127 ? 224 SER   B OG  1 
ATOM   5096 N  N   . GLY   B 2 142 ? 5.38914  20.48575  85.94283  1.000 128.74888 ? 225 GLY   B N   1 
ATOM   5097 C  CA  . GLY   B 2 142 ? 5.02734  20.86290  87.29647  1.000 125.45990 ? 225 GLY   B CA  1 
ATOM   5098 C  C   . GLY   B 2 142 ? 4.56259  22.30160  87.40994  1.000 124.40690 ? 225 GLY   B C   1 
ATOM   5099 O  O   . GLY   B 2 142 ? 5.06424  23.18334  86.71225  1.000 121.84063 ? 225 GLY   B O   1 
ATOM   5100 N  N   . ILE   B 2 150 ? 14.94909 29.68217  76.82297  1.000 92.39180  ? 421 ILE   B N   1 
ATOM   5101 C  CA  . ILE   B 2 150 ? 15.50378 30.98891  77.15225  1.000 107.93433 ? 421 ILE   B CA  1 
ATOM   5102 C  C   . ILE   B 2 150 ? 16.15787 30.96120  78.52861  1.000 110.95778 ? 421 ILE   B C   1 
ATOM   5103 O  O   . ILE   B 2 150 ? 17.33070 31.30593  78.67696  1.000 104.17989 ? 421 ILE   B O   1 
ATOM   5104 C  CB  . ILE   B 2 150 ? 14.42383 32.08522  77.08968  1.000 106.71261 ? 421 ILE   B CB  1 
ATOM   5105 C  CG1 . ILE   B 2 150 ? 13.87039 32.21343  75.66897  1.000 99.19567  ? 421 ILE   B CG1 1 
ATOM   5106 C  CG2 . ILE   B 2 150 ? 14.98454 33.41535  77.57322  1.000 92.10417  ? 421 ILE   B CG2 1 
ATOM   5107 C  CD1 . ILE   B 2 150 ? 12.80994 33.28401  75.52099  1.000 79.31726  ? 421 ILE   B CD1 1 
ATOM   5108 N  N   . GLY   B 2 151 ? 15.38838 30.54515  79.53569  1.000 115.49982 ? 422 GLY   B N   1 
ATOM   5109 C  CA  . GLY   B 2 151 ? 15.89902 30.55934  80.89641  1.000 102.52075 ? 422 GLY   B CA  1 
ATOM   5110 C  C   . GLY   B 2 151 ? 16.97578 29.51885  81.13757  1.000 98.08719  ? 422 GLY   B C   1 
ATOM   5111 O  O   . GLY   B 2 151 ? 17.97409 29.79126  81.81000  1.000 101.02802 ? 422 GLY   B O   1 
ATOM   5112 N  N   . PHE   B 2 152 ? 16.79367 28.31594  80.59369  1.000 96.49499  ? 423 PHE   B N   1 
ATOM   5113 C  CA  . PHE   B 2 152 ? 17.72244 27.21477  80.80493  1.000 95.41863  ? 423 PHE   B CA  1 
ATOM   5114 C  C   . PHE   B 2 152 ? 18.60530 26.95495  79.58952  1.000 98.61454  ? 423 PHE   B C   1 
ATOM   5115 O  O   . PHE   B 2 152 ? 19.16092 25.85930  79.45533  1.000 94.38949  ? 423 PHE   B O   1 
ATOM   5116 C  CB  . PHE   B 2 152 ? 16.95505 25.94994  81.18690  1.000 98.31864  ? 423 PHE   B CB  1 
ATOM   5117 C  CG  . PHE   B 2 152 ? 15.88122 26.18243  82.21127  1.000 103.37906 ? 423 PHE   B CG  1 
ATOM   5118 C  CD1 . PHE   B 2 152 ? 16.19463 26.26895  83.55703  1.000 98.76813  ? 423 PHE   B CD1 1 
ATOM   5119 C  CD2 . PHE   B 2 152 ? 14.55712 26.31969  81.82698  1.000 110.61690 ? 423 PHE   B CD2 1 
ATOM   5120 C  CE1 . PHE   B 2 152 ? 15.20700 26.48725  84.49899  1.000 98.19558  ? 423 PHE   B CE1 1 
ATOM   5121 C  CE2 . PHE   B 2 152 ? 13.56588 26.53424  82.76493  1.000 111.07686 ? 423 PHE   B CE2 1 
ATOM   5122 C  CZ  . PHE   B 2 152 ? 13.89141 26.61778  84.10268  1.000 105.50515 ? 423 PHE   B CZ  1 
ATOM   5123 N  N   . GLU   B 2 153 ? 18.74193 27.93783  78.70347  1.000 103.26368 ? 424 GLU   B N   1 
ATOM   5124 C  CA  . GLU   B 2 153 ? 19.61825 27.85511  77.54038  1.000 100.54768 ? 424 GLU   B CA  1 
ATOM   5125 C  C   . GLU   B 2 153 ? 20.83303 28.76255  77.70867  1.000 98.16901  ? 424 GLU   B C   1 
ATOM   5126 O  O   . GLU   B 2 153 ? 21.28947 29.40307  76.75988  1.000 102.27844 ? 424 GLU   B O   1 
ATOM   5127 C  CB  . GLU   B 2 153 ? 18.85788 28.20624  76.26428  1.000 96.89087  ? 424 GLU   B CB  1 
ATOM   5128 C  CG  . GLU   B 2 153 ? 17.76986 27.21131  75.89846  1.000 97.56948  ? 424 GLU   B CG  1 
ATOM   5129 C  CD  . GLU   B 2 153 ? 18.33076 25.87506  75.45467  1.000 103.73209 ? 424 GLU   B CD  1 
ATOM   5130 O  OE1 . GLU   B 2 153 ? 19.41861 25.86104  74.84120  1.000 100.50119 ? 424 GLU   B OE1 1 
ATOM   5131 O  OE2 . GLU   B 2 153 ? 17.68710 24.83875  75.72255  1.000 110.11213 ? 424 GLU   B OE2 1 
ATOM   5132 N  N   . LEU   B 2 154 ? 21.36771 28.82192  78.92791  1.000 87.60544  ? 425 LEU   B N   1 
ATOM   5133 C  CA  . LEU   B 2 154 ? 22.47143 29.71949  79.24377  1.000 78.69960  ? 425 LEU   B CA  1 
ATOM   5134 C  C   . LEU   B 2 154 ? 23.76517 29.25512  78.58684  1.000 76.58030  ? 425 LEU   B C   1 
ATOM   5135 O  O   . LEU   B 2 154 ? 24.26899 29.90819  77.66783  1.000 80.96932  ? 425 LEU   B O   1 
ATOM   5136 C  CB  . LEU   B 2 154 ? 22.65117 29.82526  80.75985  1.000 76.14277  ? 425 LEU   B CB  1 
ATOM   5137 C  CG  . LEU   B 2 154 ? 23.57559 30.93355  81.26600  1.000 72.21382  ? 425 LEU   B CG  1 
ATOM   5138 C  CD1 . LEU   B 2 154 ? 23.05754 32.29542  80.83355  1.000 75.73226  ? 425 LEU   B CD1 1 
ATOM   5139 C  CD2 . LEU   B 2 154 ? 23.71415 30.86674  82.77884  1.000 65.97014  ? 425 LEU   B CD2 1 
ATOM   5140 N  N   . VAL   B 2 155 ? 24.30783 28.12658  79.04994  1.000 71.57225  ? 426 VAL   B N   1 
ATOM   5141 C  CA  . VAL   B 2 155 ? 25.56594 27.62846  78.50228  1.000 79.81278  ? 426 VAL   B CA  1 
ATOM   5142 C  C   . VAL   B 2 155 ? 25.40568 27.23248  77.04016  1.000 85.84430  ? 426 VAL   B C   1 
ATOM   5143 O  O   . VAL   B 2 155 ? 26.34762 27.36062  76.24753  1.000 85.00853  ? 426 VAL   B O   1 
ATOM   5144 C  CB  . VAL   B 2 155 ? 26.08218 26.45122  79.35055  1.000 78.03060  ? 426 VAL   B CB  1 
ATOM   5145 C  CG1 . VAL   B 2 155 ? 27.45057 25.99681  78.86372  1.000 75.77449  ? 426 VAL   B CG1 1 
ATOM   5146 C  CG2 . VAL   B 2 155 ? 26.13596 26.84036  80.81673  1.000 77.39022  ? 426 VAL   B CG2 1 
ATOM   5147 N  N   . GLU   B 2 156 ? 24.21883 26.75942  76.65380  1.000 88.50801  ? 427 GLU   B N   1 
ATOM   5148 C  CA  . GLU   B 2 156 ? 24.01779 26.28894  75.28720  1.000 88.40680  ? 427 GLU   B CA  1 
ATOM   5149 C  C   . GLU   B 2 156 ? 24.12077 27.42908  74.28136  1.000 88.17077  ? 427 GLU   B C   1 
ATOM   5150 O  O   . GLU   B 2 156 ? 24.63350 27.23930  73.17243  1.000 90.19967  ? 427 GLU   B O   1 
ATOM   5151 C  CB  . GLU   B 2 156 ? 22.66213 25.59154  75.16429  1.000 93.79232  ? 427 GLU   B CB  1 
ATOM   5152 C  CG  . GLU   B 2 156 ? 22.49245 24.35926  76.04500  1.000 96.74526  ? 427 GLU   B CG  1 
ATOM   5153 C  CD  . GLU   B 2 156 ? 22.04586 24.69335  77.45829  1.000 101.63291 ? 427 GLU   B CD  1 
ATOM   5154 O  OE1 . GLU   B 2 156 ? 22.23245 25.85016  77.89169  1.000 100.54158 ? 427 GLU   B OE1 1 
ATOM   5155 O  OE2 . GLU   B 2 156 ? 21.50092 23.79643  78.13570  1.000 98.43738  ? 427 GLU   B OE2 1 
ATOM   5156 N  N   . LYS   B 2 157 ? 23.64378 28.61636  74.64403  1.000 81.04813  ? 428 LYS   B N   1 
ATOM   5157 C  CA  . LYS   B 2 157 ? 23.61119 29.75646  73.73696  1.000 81.29939  ? 428 LYS   B CA  1 
ATOM   5158 C  C   . LYS   B 2 157 ? 24.47964 30.89889  74.25113  1.000 80.61006  ? 428 LYS   B C   1 
ATOM   5159 O  O   . LYS   B 2 157 ? 24.12550 32.07471  74.14266  1.000 81.70768  ? 428 LYS   B O   1 
ATOM   5160 C  CB  . LYS   B 2 157 ? 22.17554 30.21960  73.50242  1.000 88.03400  ? 428 LYS   B CB  1 
ATOM   5161 C  CG  . LYS   B 2 157 ? 21.27425 29.11746  72.96652  1.000 101.93766 ? 428 LYS   B CG  1 
ATOM   5162 C  CD  . LYS   B 2 157 ? 20.14769 29.66764  72.10951  1.000 108.12042 ? 428 LYS   B CD  1 
ATOM   5163 C  CE  . LYS   B 2 157 ? 19.37845 28.53913  71.43890  1.000 98.25230  ? 428 LYS   B CE  1 
ATOM   5164 N  NZ  . LYS   B 2 157 ? 18.36971 29.04309  70.46725  1.000 93.51457  ? 428 LYS   B NZ  1 
ATOM   5165 N  N   . LEU   B 2 158 ? 25.63484 30.55771  74.82017  1.000 81.52355  ? 429 LEU   B N   1 
ATOM   5166 C  CA  . LEU   B 2 158 ? 26.63845 31.55008  75.18434  1.000 82.85284  ? 429 LEU   B CA  1 
ATOM   5167 C  C   . LEU   B 2 158 ? 28.01908 31.08321  74.74564  1.000 85.55773  ? 429 LEU   B C   1 
ATOM   5168 O  O   . LEU   B 2 158 ? 28.79004 31.85811  74.17154  1.000 86.27398  ? 429 LEU   B O   1 
ATOM   5169 C  CB  . LEU   B 2 158 ? 26.62956 31.82239  76.69020  1.000 76.06606  ? 429 LEU   B CB  1 
ATOM   5170 C  CG  . LEU   B 2 158 ? 25.60986 32.82949  77.22319  1.000 74.06510  ? 429 LEU   B CG  1 
ATOM   5171 C  CD1 . LEU   B 2 158 ? 25.89408 33.14140  78.68363  1.000 70.53502  ? 429 LEU   B CD1 1 
ATOM   5172 C  CD2 . LEU   B 2 158 ? 25.61758 34.10044  76.39071  1.000 77.54809  ? 429 LEU   B CD2 1 
ATOM   5173 N  N   . PHE   B 2 159 ? 28.33586 29.81363  75.00787  1.000 77.38785  ? 430 PHE   B N   1 
ATOM   5174 C  CA  . PHE   B 2 159 ? 29.63882 29.25464  74.68279  1.000 74.78289  ? 430 PHE   B CA  1 
ATOM   5175 C  C   . PHE   B 2 159 ? 29.58905 28.08602  73.71147  1.000 82.26533  ? 430 PHE   B C   1 
ATOM   5176 O  O   . PHE   B 2 159 ? 30.60634 27.80164  73.06984  1.000 86.88687  ? 430 PHE   B O   1 
ATOM   5177 C  CB  . PHE   B 2 159 ? 30.35875 28.79084  75.96000  1.000 72.39251  ? 430 PHE   B CB  1 
ATOM   5178 C  CG  . PHE   B 2 159 ? 30.39922 29.82778  77.04596  1.000 76.08043  ? 430 PHE   B CG  1 
ATOM   5179 C  CD1 . PHE   B 2 159 ? 31.42050 30.76220  77.09305  1.000 85.04352  ? 430 PHE   B CD1 1 
ATOM   5180 C  CD2 . PHE   B 2 159 ? 29.41835 29.86436  78.02386  1.000 72.99893  ? 430 PHE   B CD2 1 
ATOM   5181 C  CE1 . PHE   B 2 159 ? 31.46065 31.71656  78.09274  1.000 78.11354  ? 430 PHE   B CE1 1 
ATOM   5182 C  CE2 . PHE   B 2 159 ? 29.45278 30.81611  79.02544  1.000 74.21431  ? 430 PHE   B CE2 1 
ATOM   5183 C  CZ  . PHE   B 2 159 ? 30.47534 31.74309  79.05990  1.000 73.59140  ? 430 PHE   B CZ  1 
ATOM   5184 N  N   . GLN   B 2 160 ? 28.45274 27.40882  73.58090  1.000 85.21003  ? 431 GLN   B N   1 
ATOM   5185 C  CA  . GLN   B 2 160 ? 28.34236 26.21246  72.75950  1.000 88.64556  ? 431 GLN   B CA  1 
ATOM   5186 C  C   . GLN   B 2 160 ? 27.71881 26.54988  71.41118  1.000 85.23833  ? 431 GLN   B C   1 
ATOM   5187 O  O   . GLN   B 2 160 ? 26.76852 27.33391  71.33138  1.000 77.57995  ? 431 GLN   B O   1 
ATOM   5188 C  CB  . GLN   B 2 160 ? 27.50994 25.14524  73.47282  1.000 87.85608  ? 431 GLN   B CB  1 
ATOM   5189 C  CG  . GLN   B 2 160 ? 27.67159 23.74474  72.90964  1.000 91.39013  ? 431 GLN   B CG  1 
ATOM   5190 C  CD  . GLN   B 2 160 ? 26.98940 22.69617  73.76543  1.000 92.36615  ? 431 GLN   B CD  1 
ATOM   5191 O  OE1 . GLN   B 2 160 ? 25.99911 22.97783  74.44046  1.000 98.42906  ? 431 GLN   B OE1 1 
ATOM   5192 N  NE2 . GLN   B 2 160 ? 27.52273 21.48023  73.74929  1.000 83.90933  ? 431 GLN   B NE2 1 
ATOM   5193 N  N   . GLY   B 2 161 ? 28.25932 25.94978  70.35327  1.000 84.11626  ? 432 GLY   B N   1 
ATOM   5194 C  CA  . GLY   B 2 161 ? 27.77866 26.20292  69.01002  1.000 82.56620  ? 432 GLY   B CA  1 
ATOM   5195 C  C   . GLY   B 2 161 ? 27.39437 24.94859  68.25375  1.000 83.52380  ? 432 GLY   B C   1 
ATOM   5196 O  O   . GLY   B 2 161 ? 27.15575 23.89754  68.85537  1.000 86.05067  ? 432 GLY   B O   1 
ATOM   5197 N  N   . GLN   B 2 162 ? 27.33334 25.04964  66.92748  1.000 84.62439  ? 433 GLN   B N   1 
ATOM   5198 C  CA  . GLN   B 2 162 ? 26.92308 23.94427  66.06297  1.000 88.54228  ? 433 GLN   B CA  1 
ATOM   5199 C  C   . GLN   B 2 162 ? 28.01771 23.70843  65.02573  1.000 87.78557  ? 433 GLN   B C   1 
ATOM   5200 O  O   . GLN   B 2 162 ? 28.11525 24.44284  64.03798  1.000 86.58074  ? 433 GLN   B O   1 
ATOM   5201 C  CB  . GLN   B 2 162 ? 25.58293 24.24371  65.39571  1.000 86.51593  ? 433 GLN   B CB  1 
ATOM   5202 C  CG  . GLN   B 2 162 ? 24.99078 23.08165  64.61214  1.000 95.35717  ? 433 GLN   B CG  1 
ATOM   5203 C  CD  . GLN   B 2 162 ? 24.32155 22.04979  65.50154  1.000 103.94154 ? 433 GLN   B CD  1 
ATOM   5204 O  OE1 . GLN   B 2 162 ? 24.32150 22.17132  66.72685  1.000 104.24507 ? 433 GLN   B OE1 1 
ATOM   5205 N  NE2 . GLN   B 2 162 ? 23.74027 21.02806  64.88423  1.000 98.71076  ? 433 GLN   B NE2 1 
ATOM   5206 N  N   . LEU   B 2 163 ? 28.83636 22.68634  65.25205  1.000 89.04246  ? 434 LEU   B N   1 
ATOM   5207 C  CA  . LEU   B 2 163 ? 29.87792 22.29773  64.31466  1.000 89.84110  ? 434 LEU   B CA  1 
ATOM   5208 C  C   . LEU   B 2 163 ? 29.29997 21.35919  63.26157  1.000 96.19689  ? 434 LEU   B C   1 
ATOM   5209 O  O   . LEU   B 2 163 ? 28.35894 20.60653  63.52415  1.000 96.64295  ? 434 LEU   B O   1 
ATOM   5210 C  CB  . LEU   B 2 163 ? 31.03144 21.61093  65.04951  1.000 86.84505  ? 434 LEU   B CB  1 
ATOM   5211 C  CG  . LEU   B 2 163 ? 32.35389 21.40403  64.30445  1.000 81.88267  ? 434 LEU   B CG  1 
ATOM   5212 C  CD1 . LEU   B 2 163 ? 33.15841 22.69332  64.27442  1.000 85.19805  ? 434 LEU   B CD1 1 
ATOM   5213 C  CD2 . LEU   B 2 163 ? 33.16099 20.27571  64.93098  1.000 77.55479  ? 434 LEU   B CD2 1 
ATOM   5214 N  N   . VAL   B 2 164 ? 29.87440 21.40503  62.06238  1.000 93.23412  ? 435 VAL   B N   1 
ATOM   5215 C  CA  . VAL   B 2 164 ? 29.42440 20.58153  60.94648  1.000 84.32893  ? 435 VAL   B CA  1 
ATOM   5216 C  C   . VAL   B 2 164 ? 30.61652 19.80838  60.40067  1.000 80.41315  ? 435 VAL   B C   1 
ATOM   5217 O  O   . VAL   B 2 164 ? 31.69649 20.37792  60.20711  1.000 79.45728  ? 435 VAL   B O   1 
ATOM   5218 C  CB  . VAL   B 2 164 ? 28.76651 21.42894  59.84114  1.000 85.85250  ? 435 VAL   B CB  1 
ATOM   5219 C  CG1 . VAL   B 2 164 ? 28.41901 20.56582  58.65042  1.000 85.10608  ? 435 VAL   B CG1 1 
ATOM   5220 C  CG2 . VAL   B 2 164 ? 27.51733 22.10112  60.37487  1.000 88.94029  ? 435 VAL   B CG2 1 
ATOM   5221 N  N   . LEU   B 2 165 ? 30.42053 18.51691  60.15713  1.000 84.84249  ? 436 LEU   B N   1 
ATOM   5222 C  CA  . LEU   B 2 165 ? 31.47253 17.62214  59.68116  1.000 87.68456  ? 436 LEU   B CA  1 
ATOM   5223 C  C   . LEU   B 2 165 ? 31.08430 17.09410  58.30158  1.000 92.26715  ? 436 LEU   B C   1 
ATOM   5224 O  O   . LEU   B 2 165 ? 30.79771 15.90472  58.13727  1.000 90.43113  ? 436 LEU   B O   1 
ATOM   5225 C  CB  . LEU   B 2 165 ? 31.71026 16.46774  60.67698  1.000 92.58097  ? 436 LEU   B CB  1 
ATOM   5226 C  CG  . LEU   B 2 165 ? 32.18044 16.78537  62.10031  1.000 98.81718  ? 436 LEU   B CG  1 
ATOM   5227 C  CD1 . LEU   B 2 165 ? 31.02041 17.19550  62.99912  1.000 92.98190  ? 436 LEU   B CD1 1 
ATOM   5228 C  CD2 . LEU   B 2 165 ? 32.92105 15.59457  62.69136  1.000 107.22456 ? 436 LEU   B CD2 1 
ATOM   5229 N  N   . ARG   B 2 166 ? 31.07415 17.98084  57.30930  1.000 92.72709  ? 437 ARG   B N   1 
ATOM   5230 C  CA  . ARG   B 2 166 ? 30.81850 17.57132  55.93517  1.000 88.13673  ? 437 ARG   B CA  1 
ATOM   5231 C  C   . ARG   B 2 166 ? 32.09701 17.03670  55.30651  1.000 83.66107  ? 437 ARG   B C   1 
ATOM   5232 O  O   . ARG   B 2 166 ? 33.15727 17.66171  55.41094  1.000 79.71604  ? 437 ARG   B O   1 
ATOM   5233 C  CB  . ARG   B 2 166 ? 30.28935 18.74081  55.10452  1.000 95.88829  ? 437 ARG   B CB  1 
ATOM   5234 C  CG  . ARG   B 2 166 ? 28.89261 19.19966  55.46210  1.000 97.60950  ? 437 ARG   B CG  1 
ATOM   5235 C  CD  . ARG   B 2 166 ? 28.34343 20.15341  54.41281  1.000 98.52178  ? 437 ARG   B CD  1 
ATOM   5236 N  NE  . ARG   B 2 166 ? 29.29267 21.20864  54.07887  1.000 104.57664 ? 437 ARG   B NE  1 
ATOM   5237 C  CZ  . ARG   B 2 166 ? 29.07001 22.15885  53.18103  1.000 116.36724 ? 437 ARG   B CZ  1 
ATOM   5238 N  NH1 . ARG   B 2 166 ? 27.93071 22.22413  52.51174  1.000 125.58907 ? 437 ARG   B NH1 1 
ATOM   5239 N  NH2 . ARG   B 2 166 ? 30.01442 23.06576  52.94777  1.000 111.67074 ? 437 ARG   B NH2 1 
ATOM   5240 N  N   . THR   B 2 167 ? 31.99948 15.88251  54.65286  1.000 84.94991  ? 438 THR   B N   1 
ATOM   5241 C  CA  . THR   B 2 167 ? 33.09213 15.37392  53.83888  1.000 85.29582  ? 438 THR   B CA  1 
ATOM   5242 C  C   . THR   B 2 167 ? 32.59760 15.14191  52.41684  1.000 71.95759  ? 438 THR   B C   1 
ATOM   5243 O  O   . THR   B 2 167 ? 31.43508 14.78723  52.18898  1.000 68.31240  ? 438 THR   B O   1 
ATOM   5244 C  CB  . THR   B 2 167 ? 33.70506 14.08617  54.42304  1.000 82.78549  ? 438 THR   B CB  1 
ATOM   5245 O  OG1 . THR   B 2 167 ? 34.76027 13.62542  53.56900  1.000 82.90834  ? 438 THR   B OG1 1 
ATOM   5246 C  CG2 . THR   B 2 167 ? 32.66757 12.99668  54.56788  1.000 72.30999  ? 438 THR   B CG2 1 
ATOM   5247 N  N   . ARG   B 2 168 ? 33.49811 15.35808  51.46177  1.000 67.57946  ? 439 ARG   B N   1 
ATOM   5248 C  CA  . ARG   B 2 168 ? 33.16050 15.45146  50.04735  1.000 66.88103  ? 439 ARG   B CA  1 
ATOM   5249 C  C   . ARG   B 2 168 ? 33.86824 14.34133  49.28588  1.000 68.63227  ? 439 ARG   B C   1 
ATOM   5250 O  O   . ARG   B 2 168 ? 35.09588 14.22094  49.35669  1.000 71.25896  ? 439 ARG   B O   1 
ATOM   5251 C  CB  . ARG   B 2 168 ? 33.55728 16.82376  49.49939  1.000 66.17972  ? 439 ARG   B CB  1 
ATOM   5252 C  CG  . ARG   B 2 168 ? 33.36939 17.01077  48.00762  1.000 61.51728  ? 439 ARG   B CG  1 
ATOM   5253 C  CD  . ARG   B 2 168 ? 33.87799 18.38306  47.60068  1.000 57.18790  ? 439 ARG   B CD  1 
ATOM   5254 N  NE  . ARG   B 2 168 ? 33.73189 18.64036  46.17421  1.000 56.02082  ? 439 ARG   B NE  1 
ATOM   5255 C  CZ  . ARG   B 2 168 ? 34.13832 19.75013  45.57348  1.000 57.98083  ? 439 ARG   B CZ  1 
ATOM   5256 N  NH1 . ARG   B 2 168 ? 34.72405 20.72577  46.24817  1.000 69.83718  ? 439 ARG   B NH1 1 
ATOM   5257 N  NH2 . ARG   B 2 168 ? 33.95320 19.88441  44.26346  1.000 67.95752  ? 439 ARG   B NH2 1 
ATOM   5258 N  N   . CYS   B 2 169 ? 33.09708 13.53617  48.56003  1.000 63.76359  ? 440 CYS   B N   1 
ATOM   5259 C  CA  . CYS   B 2 169 ? 33.66769 12.47225  47.73361  1.000 64.93787  ? 440 CYS   B CA  1 
ATOM   5260 C  C   . CYS   B 2 169 ? 34.21547 13.09748  46.45850  1.000 63.16662  ? 440 CYS   B C   1 
ATOM   5261 O  O   . CYS   B 2 169 ? 33.46117 13.41393  45.53977  1.000 65.95823  ? 440 CYS   B O   1 
ATOM   5262 C  CB  . CYS   B 2 169 ? 32.62495 11.40881  47.41402  1.000 70.57389  ? 440 CYS   B CB  1 
ATOM   5263 S  SG  . CYS   B 2 169 ? 33.14871 10.27207  46.10178  1.000 78.12040  ? 440 CYS   B SG  1 
ATOM   5264 N  N   . LEU   B 2 170 ? 35.54021 13.24934  46.38147  1.000 60.85942  ? 441 LEU   B N   1 
ATOM   5265 C  CA  . LEU   B 2 170 ? 36.14249 14.01202  45.29041  1.000 63.81478  ? 441 LEU   B CA  1 
ATOM   5266 C  C   . LEU   B 2 170 ? 35.81812 13.44814  43.91055  1.000 64.35407  ? 441 LEU   B C   1 
ATOM   5267 O  O   . LEU   B 2 170 ? 36.03346 14.13959  42.90854  1.000 64.98184  ? 441 LEU   B O   1 
ATOM   5268 C  CB  . LEU   B 2 170 ? 37.65659 14.08809  45.48048  1.000 66.51364  ? 441 LEU   B CB  1 
ATOM   5269 C  CG  . LEU   B 2 170 ? 38.12945 15.03497  46.58188  1.000 66.64588  ? 441 LEU   B CG  1 
ATOM   5270 C  CD1 . LEU   B 2 170 ? 39.63130 14.92439  46.76338  1.000 72.03610  ? 441 LEU   B CD1 1 
ATOM   5271 C  CD2 . LEU   B 2 170 ? 37.73044 16.47397  46.27186  1.000 67.70361  ? 441 LEU   B CD2 1 
ATOM   5272 N  N   . GLU   B 2 171 ? 35.30439 12.22033  43.82895  1.000 59.69081  ? 442 GLU   B N   1 
ATOM   5273 C  CA  . GLU   B 2 171 ? 34.88939 11.67481  42.53627  1.000 62.44714  ? 442 GLU   B CA  1 
ATOM   5274 C  C   . GLU   B 2 171 ? 33.55725 12.27375  42.09201  1.000 62.37648  ? 442 GLU   B C   1 
ATOM   5275 O  O   . GLU   B 2 171 ? 33.51017 13.10136  41.17696  1.000 63.19213  ? 442 GLU   B O   1 
ATOM   5276 C  CB  . GLU   B 2 171 ? 34.81427 10.14656  42.60688  1.000 69.41105  ? 442 GLU   B CB  1 
ATOM   5277 C  CG  . GLU   B 2 171 ? 36.11049 9.44763   42.22894  1.000 73.93112  ? 442 GLU   B CG  1 
ATOM   5278 C  CD  . GLU   B 2 171 ? 36.31839 9.36714   40.72862  1.000 72.57639  ? 442 GLU   B CD  1 
ATOM   5279 O  OE1 . GLU   B 2 171 ? 35.48284 9.91092   39.97592  1.000 66.01098  ? 442 GLU   B OE1 1 
ATOM   5280 O  OE2 . GLU   B 2 171 ? 37.31614 8.75122   40.30039  1.000 74.59668  ? 442 GLU   B OE2 1 
ATOM   5281 N  N   . CYS   B 2 172 ? 32.46049 11.86256  42.73058  1.000 59.85622  ? 443 CYS   B N   1 
ATOM   5282 C  CA  . CYS   B 2 172 ? 31.14907 12.40458  42.39627  1.000 56.58580  ? 443 CYS   B CA  1 
ATOM   5283 C  C   . CYS   B 2 172 ? 30.90766 13.78416  42.99535  1.000 53.96369  ? 443 CYS   B C   1 
ATOM   5284 O  O   . CYS   B 2 172 ? 29.89568 14.41309  42.66545  1.000 53.94403  ? 443 CYS   B O   1 
ATOM   5285 C  CB  . CYS   B 2 172 ? 30.04548 11.44737  42.85594  1.000 58.27253  ? 443 CYS   B CB  1 
ATOM   5286 S  SG  . CYS   B 2 172 ? 29.83554 11.34370  44.64868  1.000 65.63848  ? 443 CYS   B SG  1 
ATOM   5287 N  N   . GLU   B 2 173 ? 31.80413 14.25871  43.86348  1.000 57.11254  ? 444 GLU   B N   1 
ATOM   5288 C  CA  . GLU   B 2 173 ? 31.70906 15.59026  44.46625  1.000 54.43823  ? 444 GLU   B CA  1 
ATOM   5289 C  C   . GLU   B 2 173 ? 30.39368 15.76876  45.21852  1.000 56.33193  ? 444 GLU   B C   1 
ATOM   5290 O  O   . GLU   B 2 173 ? 29.74490 16.81370  45.14015  1.000 64.96192  ? 444 GLU   B O   1 
ATOM   5291 C  CB  . GLU   B 2 173 ? 31.91045 16.68231  43.41597  1.000 54.53330  ? 444 GLU   B CB  1 
ATOM   5292 C  CG  . GLU   B 2 173 ? 33.29536 16.62959  42.79308  1.000 55.91076  ? 444 GLU   B CG  1 
ATOM   5293 C  CD  . GLU   B 2 173 ? 33.47122 17.60504  41.65349  1.000 51.27390  ? 444 GLU   B CD  1 
ATOM   5294 O  OE1 . GLU   B 2 173 ? 32.59300 18.47273  41.46696  1.000 55.14200  ? 444 GLU   B OE1 1 
ATOM   5295 O  OE2 . GLU   B 2 173 ? 34.49080 17.49800  40.94083  1.000 45.71302  ? 444 GLU   B OE2 1 
ATOM   5296 N  N   . SER   B 2 174 ? 30.00155 14.73492  45.95560  1.000 55.31265  ? 445 SER   B N   1 
ATOM   5297 C  CA  . SER   B 2 174 ? 28.83941 14.78350  46.82665  1.000 60.18824  ? 445 SER   B CA  1 
ATOM   5298 C  C   . SER   B 2 174 ? 29.27909 15.02642  48.26416  1.000 72.00027  ? 445 SER   B C   1 
ATOM   5299 O  O   . SER   B 2 174 ? 30.35917 14.60028  48.68645  1.000 76.09639  ? 445 SER   B O   1 
ATOM   5300 C  CB  . SER   B 2 174 ? 28.02908 13.48871  46.74177  1.000 61.85153  ? 445 SER   B CB  1 
ATOM   5301 O  OG  . SER   B 2 174 ? 27.59127 13.24800  45.41620  1.000 65.58328  ? 445 SER   B OG  1 
ATOM   5302 N  N   . LEU   B 2 175 ? 28.42223 15.71629  49.01104  1.000 70.71215  ? 446 LEU   B N   1 
ATOM   5303 C  CA  . LEU   B 2 175 ? 28.68984 16.10638  50.38782  1.000 73.26534  ? 446 LEU   B CA  1 
ATOM   5304 C  C   . LEU   B 2 175 ? 27.86441 15.24442  51.33170  1.000 77.40685  ? 446 LEU   B C   1 
ATOM   5305 O  O   . LEU   B 2 175 ? 26.65127 15.10104  51.14496  1.000 69.46059  ? 446 LEU   B O   1 
ATOM   5306 C  CB  . LEU   B 2 175 ? 28.35682 17.58511  50.61426  1.000 74.88151  ? 446 LEU   B CB  1 
ATOM   5307 C  CG  . LEU   B 2 175 ? 29.31224 18.68454  50.13663  1.000 81.08097  ? 446 LEU   B CG  1 
ATOM   5308 C  CD1 . LEU   B 2 175 ? 30.67527 18.53194  50.79258  1.000 82.42168  ? 446 LEU   B CD1 1 
ATOM   5309 C  CD2 . LEU   B 2 175 ? 29.43638 18.72514  48.61638  1.000 78.09533  ? 446 LEU   B CD2 1 
ATOM   5310 N  N   . THR   B 2 176 ? 28.51812 14.67372  52.33934  1.000 77.63673  ? 447 THR   B N   1 
ATOM   5311 C  CA  . THR   B 2 176 ? 27.83160 14.01489  53.44155  1.000 74.36199  ? 447 THR   B CA  1 
ATOM   5312 C  C   . THR   B 2 176 ? 28.04312 14.84562  54.69926  1.000 80.55516  ? 447 THR   B C   1 
ATOM   5313 O  O   . THR   B 2 176 ? 29.18348 15.17609  55.04764  1.000 75.52808  ? 447 THR   B O   1 
ATOM   5314 C  CB  . THR   B 2 176 ? 28.33023 12.58236  53.64384  1.000 77.92568  ? 447 THR   B CB  1 
ATOM   5315 O  OG1 . THR   B 2 176 ? 29.72390 12.59875  53.96078  1.000 78.63489  ? 447 THR   B OG1 1 
ATOM   5316 C  CG2 . THR   B 2 176 ? 28.11432 11.75947  52.38162  1.000 78.23386  ? 447 THR   B CG2 1 
ATOM   5317 N  N   . GLU   B 2 177 ? 26.94425 15.18619  55.36680  1.000 87.66509  ? 448 GLU   B N   1 
ATOM   5318 C  CA  . GLU   B 2 177 ? 26.93356 16.17908  56.43037  1.000 89.03043  ? 448 GLU   B CA  1 
ATOM   5319 C  C   . GLU   B 2 177 ? 26.59249 15.53663  57.76811  1.000 91.34782  ? 448 GLU   B C   1 
ATOM   5320 O  O   . GLU   B 2 177 ? 25.70422 14.68238  57.85212  1.000 95.23712  ? 448 GLU   B O   1 
ATOM   5321 C  CB  . GLU   B 2 177 ? 25.92742 17.29090  56.11252  1.000 91.26312  ? 448 GLU   B CB  1 
ATOM   5322 C  CG  . GLU   B 2 177 ? 25.78751 18.35282  57.19018  1.000 93.39859  ? 448 GLU   B CG  1 
ATOM   5323 C  CD  . GLU   B 2 177 ? 24.92490 19.51800  56.74541  1.000 101.16265 ? 448 GLU   B CD  1 
ATOM   5324 O  OE1 . GLU   B 2 177 ? 24.85083 19.77187  55.52434  1.000 110.36005 ? 448 GLU   B OE1 1 
ATOM   5325 O  OE2 . GLU   B 2 177 ? 24.31777 20.17716  57.61523  1.000 99.10978  ? 448 GLU   B OE2 1 
ATOM   5326 N  N   . ARG   B 2 178 ? 27.30699 15.95555  58.81075  1.000 84.28440  ? 449 ARG   B N   1 
ATOM   5327 C  CA  . ARG   B 2 178 ? 27.02814 15.54026  60.17611  1.000 80.59208  ? 449 ARG   B CA  1 
ATOM   5328 C  C   . ARG   B 2 178 ? 27.12829 16.75859  61.08109  1.000 91.86814  ? 449 ARG   B C   1 
ATOM   5329 O  O   . ARG   B 2 178 ? 27.85983 17.70765  60.78725  1.000 94.82694  ? 449 ARG   B O   1 
ATOM   5330 C  CB  . ARG   B 2 178 ? 27.99335 14.44655  60.64912  1.000 82.09174  ? 449 ARG   B CB  1 
ATOM   5331 C  CG  . ARG   B 2 178 ? 27.32569 13.33339  61.43805  1.000 91.82695  ? 449 ARG   B CG  1 
ATOM   5332 C  CD  . ARG   B 2 178 ? 28.35543 12.40850  62.06130  1.000 100.58269 ? 449 ARG   B CD  1 
ATOM   5333 N  NE  . ARG   B 2 178 ? 29.03218 13.03463  63.19047  1.000 106.57597 ? 449 ARG   B NE  1 
ATOM   5334 C  CZ  . ARG   B 2 178 ? 30.05396 12.49779  63.84282  1.000 112.77136 ? 449 ARG   B CZ  1 
ATOM   5335 N  NH1 . ARG   B 2 178 ? 30.56222 11.32861  63.48971  1.000 108.24687 ? 449 ARG   B NH1 1 
ATOM   5336 N  NH2 . ARG   B 2 178 ? 30.57994 13.15088  64.87463  1.000 121.92645 ? 449 ARG   B NH2 1 
ATOM   5337 N  N   . ARG   B 2 179 ? 26.38556 16.72819  62.18402  1.000 97.84268  ? 450 ARG   B N   1 
ATOM   5338 C  CA  . ARG   B 2 179 ? 26.30158 17.85899  63.09636  1.000 95.65888  ? 450 ARG   B CA  1 
ATOM   5339 C  C   . ARG   B 2 179 ? 26.80450 17.45852  64.47623  1.000 94.09570  ? 450 ARG   B C   1 
ATOM   5340 O  O   . ARG   B 2 179 ? 26.58805 16.32835  64.92475  1.000 96.12439  ? 450 ARG   B O   1 
ATOM   5341 C  CB  . ARG   B 2 179 ? 24.86412 18.38416  63.18998  1.000 90.99088  ? 450 ARG   B CB  1 
ATOM   5342 C  CG  . ARG   B 2 179 ? 24.04315 18.15938  61.92850  1.000 92.52071  ? 450 ARG   B CG  1 
ATOM   5343 C  CD  . ARG   B 2 179 ? 22.98089 19.23120  61.74509  1.000 94.09666  ? 450 ARG   B CD  1 
ATOM   5344 N  NE  . ARG   B 2 179 ? 23.51429 20.41570  61.08269  1.000 94.08219  ? 450 ARG   B NE  1 
ATOM   5345 C  CZ  . ARG   B 2 179 ? 22.79044 21.47139  60.73615  1.000 99.34707  ? 450 ARG   B CZ  1 
ATOM   5346 N  NH1 . ARG   B 2 179 ? 21.49320 21.53350  60.98863  1.000 101.74995 ? 450 ARG   B NH1 1 
ATOM   5347 N  NH2 . ARG   B 2 179 ? 23.38257 22.48950  60.11846  1.000 102.32026 ? 450 ARG   B NH2 1 
ATOM   5348 N  N   . GLU   B 2 180 ? 27.47556 18.39586  65.14240  1.000 88.18430  ? 451 GLU   B N   1 
ATOM   5349 C  CA  . GLU   B 2 180 ? 28.02383 18.18033  66.47297  1.000 90.61297  ? 451 GLU   B CA  1 
ATOM   5350 C  C   . GLU   B 2 180 ? 27.93376 19.47867  67.26083  1.000 92.72713  ? 451 GLU   B C   1 
ATOM   5351 O  O   . GLU   B 2 180 ? 27.59822 20.53615  66.72345  1.000 93.79422  ? 451 GLU   B O   1 
ATOM   5352 C  CB  . GLU   B 2 180 ? 29.47966 17.70372  66.41749  1.000 89.10299  ? 451 GLU   B CB  1 
ATOM   5353 C  CG  . GLU   B 2 180 ? 29.66238 16.20404  66.29585  1.000 101.59874 ? 451 GLU   B CG  1 
ATOM   5354 C  CD  . GLU   B 2 180 ? 31.12038 15.79972  66.39839  1.000 112.72878 ? 451 GLU   B CD  1 
ATOM   5355 O  OE1 . GLU   B 2 180 ? 31.99186 16.67457  66.21081  1.000 108.00550 ? 451 GLU   B OE1 1 
ATOM   5356 O  OE2 . GLU   B 2 180 ? 31.39606 14.61265  66.67180  1.000 133.25412 ? 451 GLU   B OE2 1 
ATOM   5357 N  N   . ASP   B 2 181 ? 28.26685 19.39100  68.54435  1.000 91.67730  ? 452 ASP   B N   1 
ATOM   5358 C  CA  . ASP   B 2 181 ? 28.32030 20.54704  69.42312  1.000 88.45517  ? 452 ASP   B CA  1 
ATOM   5359 C  C   . ASP   B 2 181 ? 29.74856 20.75565  69.90908  1.000 90.41927  ? 452 ASP   B C   1 
ATOM   5360 O  O   . ASP   B 2 181 ? 30.57480 19.83893  69.88869  1.000 90.04515  ? 452 ASP   B O   1 
ATOM   5361 C  CB  . ASP   B 2 181 ? 27.37004 20.38289  70.61527  1.000 87.20279  ? 452 ASP   B CB  1 
ATOM   5362 C  CG  . ASP   B 2 181 ? 25.91330 20.36108  70.19783  1.000 81.97101  ? 452 ASP   B CG  1 
ATOM   5363 O  OD1 . ASP   B 2 181 ? 25.52982 21.17519  69.33144  1.000 78.29000  ? 452 ASP   B OD1 1 
ATOM   5364 O  OD2 . ASP   B 2 181 ? 25.15326 19.52625  70.73161  1.000 85.29618  ? 452 ASP   B OD2 1 
ATOM   5365 N  N   . PHE   B 2 182 ? 30.03324 21.98043  70.34640  1.000 88.27563  ? 453 PHE   B N   1 
ATOM   5366 C  CA  . PHE   B 2 182 ? 31.37441 22.33172  70.78889  1.000 85.83731  ? 453 PHE   B CA  1 
ATOM   5367 C  C   . PHE   B 2 182 ? 31.30414 23.56729  71.67329  1.000 85.84282  ? 453 PHE   B C   1 
ATOM   5368 O  O   . PHE   B 2 182 ? 30.49700 24.46683  71.42889  1.000 87.04748  ? 453 PHE   B O   1 
ATOM   5369 C  CB  . PHE   B 2 182 ? 32.30522 22.58902  69.59650  1.000 84.43606  ? 453 PHE   B CB  1 
ATOM   5370 C  CG  . PHE   B 2 182 ? 31.94918 23.81555  68.80072  1.000 88.44253  ? 453 PHE   B CG  1 
ATOM   5371 C  CD1 . PHE   B 2 182 ? 30.95121 23.77036  67.84122  1.000 88.93480  ? 453 PHE   B CD1 1 
ATOM   5372 C  CD2 . PHE   B 2 182 ? 32.61604 25.01273  69.00983  1.000 91.57899  ? 453 PHE   B CD2 1 
ATOM   5373 C  CE1 . PHE   B 2 182 ? 30.62239 24.89514  67.10777  1.000 89.02506  ? 453 PHE   B CE1 1 
ATOM   5374 C  CE2 . PHE   B 2 182 ? 32.29086 26.14138  68.28014  1.000 93.41425  ? 453 PHE   B CE2 1 
ATOM   5375 C  CZ  . PHE   B 2 182 ? 31.29294 26.08186  67.32776  1.000 94.12430  ? 453 PHE   B CZ  1 
ATOM   5376 N  N   . GLN   B 2 183 ? 32.15674 23.60216  72.69647  1.000 88.54087  ? 454 GLN   B N   1 
ATOM   5377 C  CA  . GLN   B 2 183 ? 32.31806 24.77559  73.54477  1.000 84.75208  ? 454 GLN   B CA  1 
ATOM   5378 C  C   . GLN   B 2 183 ? 33.67438 25.43420  73.33041  1.000 81.53987  ? 454 GLN   B C   1 
ATOM   5379 O  O   . GLN   B 2 183 ? 33.74634 26.62170  73.00099  1.000 73.09316  ? 454 GLN   B O   1 
ATOM   5380 C  CB  . GLN   B 2 183 ? 32.13864 24.39733  75.02189  1.000 87.38639  ? 454 GLN   B CB  1 
ATOM   5381 C  CG  . GLN   B 2 183 ? 30.77563 23.82282  75.36460  1.000 89.08386  ? 454 GLN   B CG  1 
ATOM   5382 C  CD  . GLN   B 2 183 ? 30.63218 23.51795  76.84305  1.000 78.35877  ? 454 GLN   B CD  1 
ATOM   5383 O  OE1 . GLN   B 2 183 ? 31.49682 23.86726  77.64697  1.000 72.93006  ? 454 GLN   B OE1 1 
ATOM   5384 N  NE2 . GLN   B 2 183 ? 29.53728 22.86171  77.20915  1.000 71.79628  ? 454 GLN   B NE2 1 
ATOM   5385 N  N   . ASP   B 2 184 ? 34.75624 24.68477  73.50715  1.000 87.89081  ? 455 ASP   B N   1 
ATOM   5386 C  CA  . ASP   B 2 184 ? 36.10850 25.18236  73.31584  1.000 81.17189  ? 455 ASP   B CA  1 
ATOM   5387 C  C   . ASP   B 2 184 ? 36.61696 24.81109  71.92795  1.000 76.78871  ? 455 ASP   B C   1 
ATOM   5388 O  O   . ASP   B 2 184 ? 36.12137 23.88307  71.28381  1.000 74.14027  ? 455 ASP   B O   1 
ATOM   5389 C  CB  . ASP   B 2 184 ? 37.04719 24.61928  74.38626  1.000 84.52691  ? 455 ASP   B CB  1 
ATOM   5390 C  CG  . ASP   B 2 184 ? 36.49077 24.77342  75.78843  1.000 88.17830  ? 455 ASP   B CG  1 
ATOM   5391 O  OD1 . ASP   B 2 184 ? 35.39767 25.35961  75.93584  1.000 95.69847  ? 455 ASP   B OD1 1 
ATOM   5392 O  OD2 . ASP   B 2 184 ? 37.14409 24.30478  76.74358  1.000 80.90046  ? 455 ASP   B OD2 1 
ATOM   5393 N  N   . ILE   B 2 185 ? 37.62061 25.55606  71.47117  1.000 78.42643  ? 456 ILE   B N   1 
ATOM   5394 C  CA  . ILE   B 2 185 ? 38.24752 25.33281  70.16804  1.000 82.94293  ? 456 ILE   B CA  1 
ATOM   5395 C  C   . ILE   B 2 185 ? 39.74056 25.16962  70.42756  1.000 86.87330  ? 456 ILE   B C   1 
ATOM   5396 O  O   . ILE   B 2 185 ? 40.50560 26.14024  70.39325  1.000 90.88829  ? 456 ILE   B O   1 
ATOM   5397 C  CB  . ILE   B 2 185 ? 37.97398 26.46904  69.17711  1.000 75.05007  ? 456 ILE   B CB  1 
ATOM   5398 C  CG1 . ILE   B 2 185 ? 36.46868 26.70889  69.04268  1.000 75.26151  ? 456 ILE   B CG1 1 
ATOM   5399 C  CG2 . ILE   B 2 185 ? 38.57919 26.14837  67.81829  1.000 79.15052  ? 456 ILE   B CG2 1 
ATOM   5400 C  CD1 . ILE   B 2 185 ? 36.11027 27.81148  68.07229  1.000 73.56774  ? 456 ILE   B CD1 1 
ATOM   5401 N  N   . SER   B 2 186 ? 40.16748 23.93785  70.70073  1.000 91.36865  ? 457 SER   B N   1 
ATOM   5402 C  CA  . SER   B 2 186 ? 41.58092 23.66841  70.92316  1.000 93.82672  ? 457 SER   B CA  1 
ATOM   5403 C  C   . SER   B 2 186 ? 42.37242 23.93002  69.64767  1.000 91.08260  ? 457 SER   B C   1 
ATOM   5404 O  O   . SER   B 2 186 ? 41.94880 23.56532  68.54748  1.000 93.16061  ? 457 SER   B O   1 
ATOM   5405 C  CB  . SER   B 2 186 ? 41.77799 22.22593  71.38975  1.000 99.04070  ? 457 SER   B CB  1 
ATOM   5406 O  OG  . SER   B 2 186 ? 41.12164 21.99576  72.62485  1.000 97.97201  ? 457 SER   B OG  1 
ATOM   5407 N  N   . VAL   B 2 187 ? 43.52973 24.56614  69.80004  1.000 94.14215  ? 458 VAL   B N   1 
ATOM   5408 C  CA  . VAL   B 2 187 ? 44.27793 25.08212  68.65619  1.000 101.49063 ? 458 VAL   B CA  1 
ATOM   5409 C  C   . VAL   B 2 187 ? 45.77695 25.00289  68.93139  1.000 104.95658 ? 458 VAL   B C   1 
ATOM   5410 O  O   . VAL   B 2 187 ? 46.22431 25.34935  70.03481  1.000 104.22829 ? 458 VAL   B O   1 
ATOM   5411 C  CB  . VAL   B 2 187 ? 43.83366 26.51858  68.33061  1.000 95.96127  ? 458 VAL   B CB  1 
ATOM   5412 C  CG1 . VAL   B 2 187 ? 45.00016 27.35798  67.86342  1.000 94.63341  ? 458 VAL   B CG1 1 
ATOM   5413 C  CG2 . VAL   B 2 187 ? 42.73116 26.50693  67.28030  1.000 95.07518  ? 458 VAL   B CG2 1 
ATOM   5414 N  N   . PRO   B 2 188 ? 46.58231 24.54721  67.97485  1.000 103.94890 ? 459 PRO   B N   1 
ATOM   5415 C  CA  . PRO   B 2 188 ? 48.03175 24.47932  68.18252  1.000 101.11180 ? 459 PRO   B CA  1 
ATOM   5416 C  C   . PRO   B 2 188 ? 48.70457 25.81740  67.89662  1.000 108.12415 ? 459 PRO   B C   1 
ATOM   5417 O  O   . PRO   B 2 188 ? 48.08779 26.77442  67.42849  1.000 102.78223 ? 459 PRO   B O   1 
ATOM   5418 C  CB  . PRO   B 2 188 ? 48.47354 23.41236  67.17839  1.000 102.39894 ? 459 PRO   B CB  1 
ATOM   5419 C  CG  . PRO   B 2 188 ? 47.49774 23.55566  66.05867  1.000 101.33676 ? 459 PRO   B CG  1 
ATOM   5420 C  CD  . PRO   B 2 188 ? 46.18100 23.95518  66.68596  1.000 103.42748 ? 459 PRO   B CD  1 
ATOM   5421 N  N   . VAL   B 2 189 ? 50.00382 25.86242  68.18068  1.000 120.72821 ? 460 VAL   B N   1 
ATOM   5422 C  CA  . VAL   B 2 189 ? 50.80664 27.07192  68.04081  1.000 121.72610 ? 460 VAL   B CA  1 
ATOM   5423 C  C   . VAL   B 2 189 ? 51.72518 26.99839  66.82509  1.000 133.17846 ? 460 VAL   B C   1 
ATOM   5424 O  O   . VAL   B 2 189 ? 51.70829 27.88520  65.97064  1.000 133.49807 ? 460 VAL   B O   1 
ATOM   5425 C  CB  . VAL   B 2 189 ? 51.61445 27.35269  69.32797  1.000 114.49693 ? 460 VAL   B CB  1 
ATOM   5426 C  CG1 . VAL   B 2 189 ? 52.65166 28.43562  69.07723  1.000 119.99870 ? 460 VAL   B CG1 1 
ATOM   5427 C  CG2 . VAL   B 2 189 ? 50.68360 27.76202  70.45467  1.000 110.90385 ? 460 VAL   B CG2 1 
ATOM   5428 N  N   . GLN   B 2 190 ? 52.54054 25.95233  66.73610  1.000 140.00570 ? 461 GLN   B N   1 
ATOM   5429 C  CA  . GLN   B 2 190 ? 53.51097 25.81076  65.66130  1.000 140.59394 ? 461 GLN   B CA  1 
ATOM   5430 C  C   . GLN   B 2 190 ? 53.28003 24.50662  64.90685  1.000 141.12817 ? 461 GLN   B C   1 
ATOM   5431 O  O   . GLN   B 2 190 ? 52.46918 23.66338  65.29906  1.000 139.53562 ? 461 GLN   B O   1 
ATOM   5432 C  CB  . GLN   B 2 190 ? 54.94463 25.88168  66.20326  1.000 142.16661 ? 461 GLN   B CB  1 
ATOM   5433 C  CG  . GLN   B 2 190 ? 55.36552 27.28586  66.61523  1.000 142.04898 ? 461 GLN   B CG  1 
ATOM   5434 C  CD  . GLN   B 2 190 ? 56.74442 27.32847  67.24187  1.000 146.78139 ? 461 GLN   B CD  1 
ATOM   5435 O  OE1 . GLN   B 2 190 ? 57.10648 26.45881  68.03391  1.000 145.68767 ? 461 GLN   B OE1 1 
ATOM   5436 N  NE2 . GLN   B 2 190 ? 57.52387 28.34413  66.88761  1.000 142.32473 ? 461 GLN   B NE2 1 
ATOM   5437 N  N   . GLU   B 2 191 ? 54.01468 24.35202  63.81075  1.000 140.32683 ? 462 GLU   B N   1 
ATOM   5438 C  CA  . GLU   B 2 191 ? 53.80028 23.28133  62.84979  1.000 139.39419 ? 462 GLU   B CA  1 
ATOM   5439 C  C   . GLU   B 2 191 ? 54.76967 22.12726  63.08771  1.000 139.73849 ? 462 GLU   B C   1 
ATOM   5440 O  O   . GLU   B 2 191 ? 55.82420 22.28310  63.70857  1.000 137.57743 ? 462 GLU   B O   1 
ATOM   5441 C  CB  . GLU   B 2 191 ? 53.95501 23.81769  61.42285  1.000 137.17879 ? 462 GLU   B CB  1 
ATOM   5442 C  CG  . GLU   B 2 191 ? 53.27276 22.98940  60.34754  1.000 138.87431 ? 462 GLU   B CG  1 
ATOM   5443 C  CD  . GLU   B 2 191 ? 53.28049 23.67987  58.99780  1.000 135.82979 ? 462 GLU   B CD  1 
ATOM   5444 O  OE1 . GLU   B 2 191 ? 53.68177 24.86154  58.93698  1.000 121.95207 ? 462 GLU   B OE1 1 
ATOM   5445 O  OE2 . GLU   B 2 191 ? 52.88571 23.04287  57.99868  1.000 139.69749 ? 462 GLU   B OE2 1 
ATOM   5446 N  N   . ASP   B 2 192 ? 54.39068 20.95647  62.58258  1.000 137.50129 ? 463 ASP   B N   1 
ATOM   5447 C  CA  . ASP   B 2 192 ? 55.22254 19.76163  62.67701  1.000 130.82120 ? 463 ASP   B CA  1 
ATOM   5448 C  C   . ASP   B 2 192 ? 54.88699 18.77446  61.56308  1.000 122.43037 ? 463 ASP   B C   1 
ATOM   5449 O  O   . ASP   B 2 192 ? 55.36322 18.90889  60.43566  1.000 108.95397 ? 463 ASP   B O   1 
ATOM   5450 C  CB  . ASP   B 2 192 ? 55.05282 19.09133  64.04181  1.000 125.26421 ? 463 ASP   B CB  1 
ATOM   5451 C  CG  . ASP   B 2 192 ? 55.74225 17.74253  64.11771  1.000 126.84208 ? 463 ASP   B CG  1 
ATOM   5452 O  OD1 . ASP   B 2 192 ? 56.97336 17.68975  63.91306  1.000 127.75378 ? 463 ASP   B OD1 1 
ATOM   5453 O  OD2 . ASP   B 2 192 ? 55.05342 16.73512  64.38434  1.000 120.70569 ? 463 ASP   B OD2 1 
ATOM   5454 N  N   . GLU   B 2 210 ? 57.66279 31.75496  61.51126  1.000 130.97425 ? 481 GLU   B N   1 
ATOM   5455 C  CA  . GLU   B 2 210 ? 57.47024 31.25916  62.86970  1.000 139.47924 ? 481 GLU   B CA  1 
ATOM   5456 C  C   . GLU   B 2 210 ? 56.30189 31.96505  63.55002  1.000 145.09167 ? 481 GLU   B C   1 
ATOM   5457 O  O   . GLU   B 2 210 ? 55.54552 31.34973  64.30131  1.000 142.47787 ? 481 GLU   B O   1 
ATOM   5458 C  CB  . GLU   B 2 210 ? 58.74879 31.43750  63.68985  1.000 137.68132 ? 481 GLU   B CB  1 
ATOM   5459 C  CG  . GLU   B 2 210 ? 59.91710 30.60017  63.19610  1.000 140.24438 ? 481 GLU   B CG  1 
ATOM   5460 C  CD  . GLU   B 2 210 ? 61.18831 30.84930  63.98275  1.000 154.38216 ? 481 GLU   B CD  1 
ATOM   5461 O  OE1 . GLU   B 2 210 ? 61.27841 31.89899  64.65400  1.000 150.83424 ? 481 GLU   B OE1 1 
ATOM   5462 O  OE2 . GLU   B 2 210 ? 62.09704 29.99413  63.93151  1.000 165.29957 ? 481 GLU   B OE2 1 
ATOM   5463 N  N   . MET   B 2 211 ? 56.16154 33.26134  63.28405  1.000 145.23178 ? 482 MET   B N   1 
ATOM   5464 C  CA  . MET   B 2 211 ? 55.04345 34.04116  63.81057  1.000 143.67723 ? 482 MET   B CA  1 
ATOM   5465 C  C   . MET   B 2 211 ? 53.80697 33.72431  62.98045  1.000 137.37836 ? 482 MET   B C   1 
ATOM   5466 O  O   . MET   B 2 211 ? 53.66770 34.18917  61.84668  1.000 131.00562 ? 482 MET   B O   1 
ATOM   5467 C  CB  . MET   B 2 211 ? 55.36605 35.53074  63.78968  1.000 147.60077 ? 482 MET   B CB  1 
ATOM   5468 C  CG  . MET   B 2 211 ? 56.47182 35.93840  64.74914  1.000 161.55625 ? 482 MET   B CG  1 
ATOM   5469 S  SD  . MET   B 2 211 ? 56.05179 35.61694  66.47379  1.000 180.72096 ? 482 MET   B SD  1 
ATOM   5470 C  CE  . MET   B 2 211 ? 54.62815 36.68279  66.68355  1.000 134.91302 ? 482 MET   B CE  1 
ATOM   5471 N  N   . LYS   B 2 212 ? 52.90580 32.92596  63.54588  1.000 132.07434 ? 483 LYS   B N   1 
ATOM   5472 C  CA  . LYS   B 2 212 ? 51.70391 32.48182  62.85520  1.000 121.86220 ? 483 LYS   B CA  1 
ATOM   5473 C  C   . LYS   B 2 212 ? 50.51869 33.33673  63.28179  1.000 116.49036 ? 483 LYS   B C   1 
ATOM   5474 O  O   . LYS   B 2 212 ? 50.27653 33.51769  64.47948  1.000 117.86719 ? 483 LYS   B O   1 
ATOM   5475 C  CB  . LYS   B 2 212 ? 51.42125 31.00920  63.15337  1.000 117.66535 ? 483 LYS   B CB  1 
ATOM   5476 C  CG  . LYS   B 2 212 ? 52.58778 30.07566  62.87456  1.000 118.38424 ? 483 LYS   B CG  1 
ATOM   5477 C  CD  . LYS   B 2 212 ? 52.90827 30.01406  61.39176  1.000 123.08670 ? 483 LYS   B CD  1 
ATOM   5478 C  CE  . LYS   B 2 212 ? 54.01856 29.01453  61.11240  1.000 124.17371 ? 483 LYS   B CE  1 
ATOM   5479 N  NZ  . LYS   B 2 212 ? 54.30871 28.89564  59.65709  1.000 122.58242 ? 483 LYS   B NZ  1 
ATOM   5480 N  N   . THR   B 2 213 ? 49.78445 33.85830  62.30383  1.000 112.39913 ? 484 THR   B N   1 
ATOM   5481 C  CA  . THR   B 2 213 ? 48.56459 34.58682  62.60807  1.000 106.85726 ? 484 THR   B CA  1 
ATOM   5482 C  C   . THR   B 2 213 ? 47.49195 33.62655  63.11439  1.000 105.99160 ? 484 THR   B C   1 
ATOM   5483 O  O   . THR   B 2 213 ? 47.60041 32.40384  62.98169  1.000 97.31670  ? 484 THR   B O   1 
ATOM   5484 C  CB  . THR   B 2 213 ? 48.05869 35.33700  61.37526  1.000 100.93685 ? 484 THR   B CB  1 
ATOM   5485 O  OG1 . THR   B 2 213 ? 46.83862 36.01758  61.69473  1.000 97.91897  ? 484 THR   B OG1 1 
ATOM   5486 C  CG2 . THR   B 2 213 ? 47.80893 34.36857  60.22815  1.000 94.20373  ? 484 THR   B CG2 1 
ATOM   5487 N  N   . LEU   B 2 214 ? 46.44211 34.19987  63.70855  1.000 104.20019 ? 485 LEU   B N   1 
ATOM   5488 C  CA  . LEU   B 2 214 ? 45.35299 33.37800  64.22620  1.000 95.64501  ? 485 LEU   B CA  1 
ATOM   5489 C  C   . LEU   B 2 214 ? 44.65817 32.60471  63.11385  1.000 94.42215  ? 485 LEU   B C   1 
ATOM   5490 O  O   . LEU   B 2 214 ? 44.09584 31.53353  63.36189  1.000 94.09539  ? 485 LEU   B O   1 
ATOM   5491 C  CB  . LEU   B 2 214 ? 44.34653 34.24923  64.97855  1.000 90.62291  ? 485 LEU   B CB  1 
ATOM   5492 C  CG  . LEU   B 2 214 ? 43.15833 33.53131  65.62428  1.000 78.28295  ? 485 LEU   B CG  1 
ATOM   5493 C  CD1 . LEU   B 2 214 ? 43.63830 32.46874  66.60119  1.000 78.22934  ? 485 LEU   B CD1 1 
ATOM   5494 C  CD2 . LEU   B 2 214 ? 42.23393 34.52151  66.31523  1.000 84.14242  ? 485 LEU   B CD2 1 
ATOM   5495 N  N   . ARG   B 2 215 ? 44.69013 33.12618  61.88583  1.000 96.02755  ? 486 ARG   B N   1 
ATOM   5496 C  CA  . ARG   B 2 215 ? 44.08535 32.42076  60.76042  1.000 97.91111  ? 486 ARG   B CA  1 
ATOM   5497 C  C   . ARG   B 2 215 ? 44.76223 31.07554  60.52172  1.000 97.71953  ? 486 ARG   B C   1 
ATOM   5498 O  O   . ARG   B 2 215 ? 44.08749 30.06145  60.30379  1.000 98.43782  ? 486 ARG   B O   1 
ATOM   5499 C  CB  . ARG   B 2 215 ? 44.15415 33.29957  59.51165  1.000 99.58153  ? 486 ARG   B CB  1 
ATOM   5500 C  CG  . ARG   B 2 215 ? 43.83069 32.59928  58.20599  1.000 102.69962 ? 486 ARG   B CG  1 
ATOM   5501 C  CD  . ARG   B 2 215 ? 43.78111 33.61139  57.07317  1.000 96.91794  ? 486 ARG   B CD  1 
ATOM   5502 N  NE  . ARG   B 2 215 ? 43.90025 32.99137  55.75968  1.000 103.44837 ? 486 ARG   B NE  1 
ATOM   5503 C  CZ  . ARG   B 2 215 ? 43.86930 33.65939  54.61470  1.000 107.02765 ? 486 ARG   B CZ  1 
ATOM   5504 N  NH1 . ARG   B 2 215 ? 43.70634 34.97214  54.58485  1.000 91.47634  ? 486 ARG   B NH1 1 
ATOM   5505 N  NH2 . ARG   B 2 215 ? 44.00547 32.99414  53.47116  1.000 115.26354 ? 486 ARG   B NH2 1 
ATOM   5506 N  N   . TRP   B 2 216 ? 46.09657 31.04571  60.57222  1.000 96.66330  ? 487 TRP   B N   1 
ATOM   5507 C  CA  . TRP   B 2 216 ? 46.82247 29.79044  60.40173  1.000 99.77089  ? 487 TRP   B CA  1 
ATOM   5508 C  C   . TRP   B 2 216 ? 46.47323 28.79740  61.50317  1.000 99.87128  ? 487 TRP   B C   1 
ATOM   5509 O  O   . TRP   B 2 216 ? 46.25160 27.60974  61.23523  1.000 101.48313 ? 487 TRP   B O   1 
ATOM   5510 C  CB  . TRP   B 2 216 ? 48.32741 30.06345  60.37961  1.000 106.47703 ? 487 TRP   B CB  1 
ATOM   5511 C  CG  . TRP   B 2 216 ? 49.17937 28.83726  60.23445  1.000 114.08179 ? 487 TRP   B CG  1 
ATOM   5512 C  CD1 . TRP   B 2 216 ? 49.65112 28.30059  59.07202  1.000 115.05136 ? 487 TRP   B CD1 1 
ATOM   5513 C  CD2 . TRP   B 2 216 ? 49.67214 28.00202  61.29040  1.000 115.46747 ? 487 TRP   B CD2 1 
ATOM   5514 N  NE1 . TRP   B 2 216 ? 50.40218 27.18099  59.33749  1.000 120.62639 ? 487 TRP   B NE1 1 
ATOM   5515 C  CE2 . TRP   B 2 216 ? 50.43034 26.97609  60.69189  1.000 120.32400 ? 487 TRP   B CE2 1 
ATOM   5516 C  CE3 . TRP   B 2 216 ? 49.54262 28.02013  62.68254  1.000 109.54614 ? 487 TRP   B CE3 1 
ATOM   5517 C  CZ2 . TRP   B 2 216 ? 51.05617 25.97863  61.43681  1.000 121.48965 ? 487 TRP   B CZ2 1 
ATOM   5518 C  CZ3 . TRP   B 2 216 ? 50.16428 27.02907  63.41966  1.000 111.88215 ? 487 TRP   B CZ3 1 
ATOM   5519 C  CH2 . TRP   B 2 216 ? 50.91199 26.02293  62.79600  1.000 118.76525 ? 487 TRP   B CH2 1 
ATOM   5520 N  N   . ALA   B 2 217 ? 46.41404 29.26899  62.75014  1.000 97.84066  ? 488 ALA   B N   1 
ATOM   5521 C  CA  . ALA   B 2 217 ? 46.11813 28.38276  63.86937  1.000 100.28219 ? 488 ALA   B CA  1 
ATOM   5522 C  C   . ALA   B 2 217 ? 44.68347 27.87038  63.82290  1.000 99.23664  ? 488 ALA   B C   1 
ATOM   5523 O  O   . ALA   B 2 217 ? 44.41514 26.74424  64.25715  1.000 99.38794  ? 488 ALA   B O   1 
ATOM   5524 C  CB  . ALA   B 2 217 ? 46.39029 29.10762  65.18556  1.000 98.13576  ? 488 ALA   B CB  1 
ATOM   5525 N  N   . ILE   B 2 218 ? 43.75302 28.67733  63.30872  1.000 96.88582  ? 489 ILE   B N   1 
ATOM   5526 C  CA  . ILE   B 2 218 ? 42.38057 28.21478  63.12882  1.000 89.80687  ? 489 ILE   B CA  1 
ATOM   5527 C  C   . ILE   B 2 218 ? 42.31201 27.18750  62.00704  1.000 95.79350  ? 489 ILE   B C   1 
ATOM   5528 O  O   . ILE   B 2 218 ? 41.57173 26.19915  62.09366  1.000 97.32076  ? 489 ILE   B O   1 
ATOM   5529 C  CB  . ILE   B 2 218 ? 41.44563 29.41009  62.86419  1.000 79.17729  ? 489 ILE   B CB  1 
ATOM   5530 C  CG1 . ILE   B 2 218 ? 41.29392 30.26185  64.12503  1.000 82.12816  ? 489 ILE   B CG1 1 
ATOM   5531 C  CG2 . ILE   B 2 218 ? 40.08306 28.93859  62.37472  1.000 80.60037  ? 489 ILE   B CG2 1 
ATOM   5532 C  CD1 . ILE   B 2 218 ? 40.42758 31.48629  63.92929  1.000 88.22576  ? 489 ILE   B CD1 1 
ATOM   5533 N  N   . SER   B 2 219 ? 43.08353 27.40237  60.93827  1.000 92.64046  ? 490 SER   B N   1 
ATOM   5534 C  CA  . SER   B 2 219 ? 43.12104 26.43650  59.84615  1.000 94.04796  ? 490 SER   B CA  1 
ATOM   5535 C  C   . SER   B 2 219 ? 43.68253 25.09936  60.31238  1.000 96.90355  ? 490 SER   B C   1 
ATOM   5536 O  O   . SER   B 2 219 ? 43.20428 24.03841  59.89614  1.000 97.42092  ? 490 SER   B O   1 
ATOM   5537 C  CB  . SER   B 2 219 ? 43.94722 26.99119  58.68580  1.000 97.06824  ? 490 SER   B CB  1 
ATOM   5538 O  OG  . SER   B 2 219 ? 43.42338 28.22672  58.23141  1.000 93.76014  ? 490 SER   B OG  1 
ATOM   5539 N  N   . GLN   B 2 220 ? 44.69480 25.12967  61.18375  1.000 94.74034  ? 491 GLN   B N   1 
ATOM   5540 C  CA  . GLN   B 2 220 ? 45.27994 23.88280  61.67275  1.000 99.05751  ? 491 GLN   B CA  1 
ATOM   5541 C  C   . GLN   B 2 220 ? 44.24555 23.00813  62.37144  1.000 102.58906 ? 491 GLN   B C   1 
ATOM   5542 O  O   . GLN   B 2 220 ? 44.38834 21.78012  62.40004  1.000 105.63848 ? 491 GLN   B O   1 
ATOM   5543 C  CB  . GLN   B 2 220 ? 46.44417 24.17336  62.62047  1.000 107.64567 ? 491 GLN   B CB  1 
ATOM   5544 C  CG  . GLN   B 2 220 ? 47.58837 24.94489  61.98967  1.000 109.93395 ? 491 GLN   B CG  1 
ATOM   5545 C  CD  . GLN   B 2 220 ? 47.94669 24.43476  60.60887  1.000 111.72532 ? 491 GLN   B CD  1 
ATOM   5546 O  OE1 . GLN   B 2 220 ? 48.25487 23.25673  60.42898  1.000 115.84826 ? 491 GLN   B OE1 1 
ATOM   5547 N  NE2 . GLN   B 2 220 ? 47.90031 25.32167  59.62144  1.000 116.05925 ? 491 GLN   B NE2 1 
ATOM   5548 N  N   . PHE   B 2 221 ? 43.20052 23.61618  62.93265  1.000 104.33165 ? 492 PHE   B N   1 
ATOM   5549 C  CA  . PHE   B 2 221 ? 42.15078 22.87629  63.62151  1.000 106.57416 ? 492 PHE   B CA  1 
ATOM   5550 C  C   . PHE   B 2 221 ? 40.97348 22.54339  62.71206  1.000 103.85582 ? 492 PHE   B C   1 
ATOM   5551 O  O   . PHE   B 2 221 ? 40.45535 21.42238  62.75987  1.000 104.40412 ? 492 PHE   B O   1 
ATOM   5552 C  CB  . PHE   B 2 221 ? 41.65779 23.67149  64.83660  1.000 101.75779 ? 492 PHE   B CB  1 
ATOM   5553 C  CG  . PHE   B 2 221 ? 40.34863 23.18033  65.39534  1.000 104.23481 ? 492 PHE   B CG  1 
ATOM   5554 C  CD1 . PHE   B 2 221 ? 40.30781 22.07846  66.23322  1.000 111.18018 ? 492 PHE   B CD1 1 
ATOM   5555 C  CD2 . PHE   B 2 221 ? 39.15920 23.82359  65.08503  1.000 94.41724  ? 492 PHE   B CD2 1 
ATOM   5556 C  CE1 . PHE   B 2 221 ? 39.10760 21.62341  66.74766  1.000 109.26492 ? 492 PHE   B CE1 1 
ATOM   5557 C  CE2 . PHE   B 2 221 ? 37.95501 23.37199  65.59532  1.000 93.88755  ? 492 PHE   B CE2 1 
ATOM   5558 C  CZ  . PHE   B 2 221 ? 37.93011 22.27106  66.42865  1.000 103.25320 ? 492 PHE   B CZ  1 
ATOM   5559 N  N   . ALA   B 2 222 ? 40.54282 23.48926  61.87636  1.000 94.05750  ? 493 ALA   B N   1 
ATOM   5560 C  CA  . ALA   B 2 222 ? 39.28126 23.34942  61.16192  1.000 89.26235  ? 493 ALA   B CA  1 
ATOM   5561 C  C   . ALA   B 2 222 ? 39.43242 22.96641  59.69506  1.000 90.55267  ? 493 ALA   B C   1 
ATOM   5562 O  O   . ALA   B 2 222 ? 38.45458 22.50476  59.09520  1.000 94.48406  ? 493 ALA   B O   1 
ATOM   5563 C  CB  . ALA   B 2 222 ? 38.47649 24.65223  61.25328  1.000 89.53799  ? 493 ALA   B CB  1 
ATOM   5564 N  N   . SER   B 2 223 ? 40.61649 23.13172  59.10134  1.000 94.01482  ? 494 SER   B N   1 
ATOM   5565 C  CA  . SER   B 2 223 ? 40.75730 22.90063  57.66629  1.000 103.27908 ? 494 SER   B CA  1 
ATOM   5566 C  C   . SER   B 2 223 ? 40.73862 21.41694  57.30722  1.000 98.05867  ? 494 SER   B C   1 
ATOM   5567 O  O   . SER   B 2 223 ? 40.34100 20.56838  58.11404  1.000 88.05012  ? 494 SER   B O   1 
ATOM   5568 C  CB  . SER   B 2 223 ? 42.03745 23.54012  57.12855  1.000 104.80944 ? 494 SER   B CB  1 
ATOM   5569 O  OG  . SER   B 2 223 ? 41.94397 24.96409  57.14387  1.000 100.49760 ? 494 SER   B OG  1 
ATOM   5570 N  N   . VAL   B 2 224 ? 41.17915 21.09998  56.08936  1.000 95.61152  ? 495 VAL   B N   1 
ATOM   5571 C  CA  . VAL   B 2 224 ? 40.89832 19.82138  55.44815  1.000 94.69439  ? 495 VAL   B CA  1 
ATOM   5572 C  C   . VAL   B 2 224 ? 42.03811 18.84146  55.68149  1.000 90.22098  ? 495 VAL   B C   1 
ATOM   5573 O  O   . VAL   B 2 224 ? 43.22025 19.19226  55.58173  1.000 90.12979  ? 495 VAL   B O   1 
ATOM   5574 C  CB  . VAL   B 2 224 ? 40.65101 20.02844  53.94233  1.000 92.40831  ? 495 VAL   B CB  1 
ATOM   5575 C  CG1 . VAL   B 2 224 ? 40.48185 18.69590  53.24123  1.000 95.16723  ? 495 VAL   B CG1 1 
ATOM   5576 C  CG2 . VAL   B 2 224 ? 39.43828 20.91337  53.72153  1.000 73.57749  ? 495 VAL   B CG2 1 
ATOM   5577 N  N   . GLU   B 2 225 ? 41.66999 17.60359  55.99888  1.000 87.01892  ? 496 GLU   B N   1 
ATOM   5578 C  CA  . GLU   B 2 225 ? 42.55698 16.45118  55.92999  1.000 86.30688  ? 496 GLU   B CA  1 
ATOM   5579 C  C   . GLU   B 2 225 ? 42.11204 15.58566  54.75885  1.000 82.62611  ? 496 GLU   B C   1 
ATOM   5580 O  O   . GLU   B 2 225 ? 40.93565 15.22259  54.66520  1.000 86.47863  ? 496 GLU   B O   1 
ATOM   5581 C  CB  . GLU   B 2 225 ? 42.52403 15.64745  57.23252  1.000 87.04229  ? 496 GLU   B CB  1 
ATOM   5582 C  CG  . GLU   B 2 225 ? 43.26446 14.32115  57.16148  1.000 90.06969  ? 496 GLU   B CG  1 
ATOM   5583 C  CD  . GLU   B 2 225 ? 43.07764 13.47657  58.40867  1.000 99.68156  ? 496 GLU   B CD  1 
ATOM   5584 O  OE1 . GLU   B 2 225 ? 42.56845 14.00960  59.41642  1.000 100.77082 ? 496 GLU   B OE1 1 
ATOM   5585 O  OE2 . GLU   B 2 225 ? 43.43605 12.27915  58.38077  1.000 98.55397  ? 496 GLU   B OE2 1 
ATOM   5586 N  N   . ARG   B 2 226 ? 43.03924 15.26708  53.86239  1.000 79.20565  ? 497 ARG   B N   1 
ATOM   5587 C  CA  . ARG   B 2 226 ? 42.69105 14.56070  52.63799  1.000 79.10542  ? 497 ARG   B CA  1 
ATOM   5588 C  C   . ARG   B 2 226 ? 42.79585 13.05348  52.83236  1.000 83.24543  ? 497 ARG   B C   1 
ATOM   5589 O  O   . ARG   B 2 226 ? 43.76638 12.55337  53.40822  1.000 94.68544  ? 497 ARG   B O   1 
ATOM   5590 C  CB  . ARG   B 2 226 ? 43.59049 15.00476  51.48390  1.000 80.44746  ? 497 ARG   B CB  1 
ATOM   5591 C  CG  . ARG   B 2 226 ? 43.08134 14.57584  50.11832  1.000 87.18883  ? 497 ARG   B CG  1 
ATOM   5592 C  CD  . ARG   B 2 226 ? 43.97266 15.08952  49.00456  1.000 83.83014  ? 497 ARG   B CD  1 
ATOM   5593 N  NE  . ARG   B 2 226 ? 44.08909 16.54267  49.01401  1.000 81.58345  ? 497 ARG   B NE  1 
ATOM   5594 C  CZ  . ARG   B 2 226 ? 43.23578 17.36648  48.42149  1.000 84.23898  ? 497 ARG   B CZ  1 
ATOM   5595 N  NH1 . ARG   B 2 226 ? 42.15856 16.91580  47.80015  1.000 83.12439  ? 497 ARG   B NH1 1 
ATOM   5596 N  NH2 . ARG   B 2 226 ? 43.47211 18.67507  48.44856  1.000 85.52204  ? 497 ARG   B NH2 1 
ATOM   5597 N  N   . ILE   B 2 227 ? 41.78488 12.33652  52.34947  1.000 79.30924  ? 498 ILE   B N   1 
ATOM   5598 C  CA  . ILE   B 2 227 ? 41.74109 10.87984  52.38843  1.000 76.75511  ? 498 ILE   B CA  1 
ATOM   5599 C  C   . ILE   B 2 227 ? 42.08562 10.37566  50.99423  1.000 74.36091  ? 498 ILE   B C   1 
ATOM   5600 O  O   . ILE   B 2 227 ? 41.28582 10.51106  50.05977  1.000 79.24786  ? 498 ILE   B O   1 
ATOM   5601 C  CB  . ILE   B 2 227 ? 40.36807 10.36128  52.83609  1.000 70.90071  ? 498 ILE   B CB  1 
ATOM   5602 C  CG1 . ILE   B 2 227 ? 40.04803 10.81636  54.25979  1.000 81.14201  ? 498 ILE   B CG1 1 
ATOM   5603 C  CG2 . ILE   B 2 227 ? 40.31415 8.84273   52.73784  1.000 71.15188  ? 498 ILE   B CG2 1 
ATOM   5604 C  CD1 . ILE   B 2 227 ? 38.71713 10.29896  54.76631  1.000 83.16596  ? 498 ILE   B CD1 1 
ATOM   5605 N  N   . VAL   B 2 228 ? 43.27559 9.78995   50.85904  1.000 73.69650  ? 499 VAL   B N   1 
ATOM   5606 C  CA  . VAL   B 2 228 ? 43.76154 9.25415   49.59200  1.000 77.66451  ? 499 VAL   B CA  1 
ATOM   5607 C  C   . VAL   B 2 228 ? 44.97563 8.37430   49.86633  1.000 81.90867  ? 499 VAL   B C   1 
ATOM   5608 O  O   . VAL   B 2 228 ? 45.81163 8.69880   50.71745  1.000 92.44093  ? 499 VAL   B O   1 
ATOM   5609 C  CB  . VAL   B 2 228 ? 44.09815 10.38482  48.59897  1.000 76.72606  ? 499 VAL   B CB  1 
ATOM   5610 C  CG1 . VAL   B 2 228 ? 45.03665 11.39996  49.23673  1.000 72.45739  ? 499 VAL   B CG1 1 
ATOM   5611 C  CG2 . VAL   B 2 228 ? 44.70188 9.82146   47.31928  1.000 84.47850  ? 499 VAL   B CG2 1 
ATOM   5612 N  N   . GLY   B 2 229 ? 45.07389 7.24812   49.16308  1.000 73.69786  ? 500 GLY   B N   1 
ATOM   5613 C  CA  . GLY   B 2 229 ? 46.21927 6.37193   49.31000  1.000 81.11660  ? 500 GLY   B CA  1 
ATOM   5614 C  C   . GLY   B 2 229 ? 45.84975 4.93351   49.60442  1.000 93.20510  ? 500 GLY   B C   1 
ATOM   5615 O  O   . GLY   B 2 229 ? 45.03118 4.33856   48.89675  1.000 95.70515  ? 500 GLY   B O   1 
ATOM   5616 N  N   . GLU   B 2 230 ? 46.45542 4.36197   50.64747  1.000 97.90241  ? 501 GLU   B N   1 
ATOM   5617 C  CA  . GLU   B 2 230 ? 46.15396 2.98494   51.02528  1.000 100.21794 ? 501 GLU   B CA  1 
ATOM   5618 C  C   . GLU   B 2 230 ? 44.70203 2.84779   51.46779  1.000 103.72348 ? 501 GLU   B C   1 
ATOM   5619 O  O   . GLU   B 2 230 ? 43.94470 2.03458   50.92567  1.000 103.63529 ? 501 GLU   B O   1 
ATOM   5620 C  CB  . GLU   B 2 230 ? 47.10650 2.52688   52.13201  1.000 97.59565  ? 501 GLU   B CB  1 
ATOM   5621 C  CG  . GLU   B 2 230 ? 48.55454 2.39158   51.68923  1.000 97.25856  ? 501 GLU   B CG  1 
ATOM   5622 C  CD  . GLU   B 2 230 ? 48.76999 1.21978   50.75137  1.000 103.98567 ? 501 GLU   B CD  1 
ATOM   5623 O  OE1 . GLU   B 2 230 ? 48.09102 0.18535   50.92386  1.000 100.18750 ? 501 GLU   B OE1 1 
ATOM   5624 O  OE2 . GLU   B 2 230 ? 49.61533 1.33440   49.83913  1.000 106.52376 ? 501 GLU   B OE2 1 
ATOM   5625 N  N   . ASP   B 2 231 ? 44.29542 3.64214   52.45469  1.000 103.77579 ? 502 ASP   B N   1 
ATOM   5626 C  CA  . ASP   B 2 231 ? 42.92134 3.64649   52.95082  1.000 101.67694 ? 502 ASP   B CA  1 
ATOM   5627 C  C   . ASP   B 2 231 ? 42.18907 4.82124   52.31243  1.000 94.89407  ? 502 ASP   B C   1 
ATOM   5628 O  O   . ASP   B 2 231 ? 42.35150 5.97058   52.73027  1.000 89.47085  ? 502 ASP   B O   1 
ATOM   5629 C  CB  . ASP   B 2 231 ? 42.88977 3.72985   54.47339  1.000 104.64355 ? 502 ASP   B CB  1 
ATOM   5630 C  CG  . ASP   B 2 231 ? 43.29954 2.43049   55.13710  1.000 118.54212 ? 502 ASP   B CG  1 
ATOM   5631 O  OD1 . ASP   B 2 231 ? 43.66347 1.47992   54.41319  1.000 117.16583 ? 502 ASP   B OD1 1 
ATOM   5632 O  OD2 . ASP   B 2 231 ? 43.25229 2.35802   56.38295  1.000 130.24502 ? 502 ASP   B OD2 1 
ATOM   5633 N  N   . LYS   B 2 232 ? 41.38608 4.52921   51.29283  1.000 94.22377  ? 503 LYS   B N   1 
ATOM   5634 C  CA  . LYS   B 2 232 ? 40.55206 5.53526   50.65987  1.000 87.02236  ? 503 LYS   B CA  1 
ATOM   5635 C  C   . LYS   B 2 232 ? 39.17898 5.55935   51.32900  1.000 81.55271  ? 503 LYS   B C   1 
ATOM   5636 O  O   . LYS   B 2 232 ? 38.90113 4.81037   52.26923  1.000 85.70589  ? 503 LYS   B O   1 
ATOM   5637 C  CB  . LYS   B 2 232 ? 40.43401 5.26841   49.15977  1.000 80.03918  ? 503 LYS   B CB  1 
ATOM   5638 C  CG  . LYS   B 2 232 ? 41.76441 5.24157   48.42466  1.000 78.79573  ? 503 LYS   B CG  1 
ATOM   5639 C  CD  . LYS   B 2 232 ? 41.56315 5.04803   46.93082  1.000 70.39755  ? 503 LYS   B CD  1 
ATOM   5640 C  CE  . LYS   B 2 232 ? 42.89275 4.92503   46.20670  1.000 69.09462  ? 503 LYS   B CE  1 
ATOM   5641 N  NZ  . LYS   B 2 232 ? 43.76624 6.10682   46.44481  1.000 72.97521  ? 503 LYS   B NZ  1 
ATOM   5642 N  N   . TYR   B 2 233 ? 38.30646 6.43450   50.84055  1.000 75.15978  ? 504 TYR   B N   1 
ATOM   5643 C  CA  . TYR   B 2 233 ? 36.95791 6.57567   51.37252  1.000 76.30478  ? 504 TYR   B CA  1 
ATOM   5644 C  C   . TYR   B 2 233 ? 35.97629 5.85164   50.46260  1.000 81.41897  ? 504 TYR   B C   1 
ATOM   5645 O  O   . TYR   B 2 233 ? 35.93996 6.10635   49.25634  1.000 87.58986  ? 504 TYR   B O   1 
ATOM   5646 C  CB  . TYR   B 2 233 ? 36.57917 8.05226   51.50132  1.000 80.55503  ? 504 TYR   B CB  1 
ATOM   5647 C  CG  . TYR   B 2 233 ? 35.09716 8.31143   51.66464  1.000 83.39537  ? 504 TYR   B CG  1 
ATOM   5648 C  CD1 . TYR   B 2 233 ? 34.47606 8.15896   52.89727  1.000 92.96189  ? 504 TYR   B CD1 1 
ATOM   5649 C  CD2 . TYR   B 2 233 ? 34.32150 8.72140   50.58679  1.000 78.83064  ? 504 TYR   B CD2 1 
ATOM   5650 C  CE1 . TYR   B 2 233 ? 33.12158 8.39812   53.05043  1.000 91.01466  ? 504 TYR   B CE1 1 
ATOM   5651 C  CE2 . TYR   B 2 233 ? 32.96687 8.96244   50.72995  1.000 80.90590  ? 504 TYR   B CE2 1 
ATOM   5652 C  CZ  . TYR   B 2 233 ? 32.37245 8.79981   51.96376  1.000 84.07990  ? 504 TYR   B CZ  1 
ATOM   5653 O  OH  . TYR   B 2 233 ? 31.02529 9.03973   52.11073  1.000 74.09369  ? 504 TYR   B OH  1 
ATOM   5654 N  N   . PHE   B 2 234 ? 35.18900 4.94695   51.03611  1.000 80.81382  ? 505 PHE   B N   1 
ATOM   5655 C  CA  . PHE   B 2 234 ? 34.18975 4.21988   50.26119  1.000 79.48673  ? 505 PHE   B CA  1 
ATOM   5656 C  C   . PHE   B 2 234 ? 32.96262 5.10433   50.08091  1.000 82.99774  ? 505 PHE   B C   1 
ATOM   5657 O  O   . PHE   B 2 234 ? 32.24594 5.38858   51.04628  1.000 80.94308  ? 505 PHE   B O   1 
ATOM   5658 C  CB  . PHE   B 2 234 ? 33.81962 2.90774   50.94440  1.000 76.32680  ? 505 PHE   B CB  1 
ATOM   5659 C  CG  . PHE   B 2 234 ? 32.71877 2.15913   50.24878  1.000 78.08552  ? 505 PHE   B CG  1 
ATOM   5660 C  CD1 . PHE   B 2 234 ? 32.99226 1.36809   49.14563  1.000 76.80475  ? 505 PHE   B CD1 1 
ATOM   5661 C  CD2 . PHE   B 2 234 ? 31.40953 2.25186   50.69299  1.000 83.80606  ? 505 PHE   B CD2 1 
ATOM   5662 C  CE1 . PHE   B 2 234 ? 31.98266 0.68145   48.50036  1.000 78.67455  ? 505 PHE   B CE1 1 
ATOM   5663 C  CE2 . PHE   B 2 234 ? 30.39534 1.56804   50.05179  1.000 85.16615  ? 505 PHE   B CE2 1 
ATOM   5664 C  CZ  . PHE   B 2 234 ? 30.68242 0.78130   48.95413  1.000 79.54107  ? 505 PHE   B CZ  1 
ATOM   5665 N  N   . CYS   B 2 235 ? 32.71804 5.54136   48.84821  1.000 84.12410  ? 506 CYS   B N   1 
ATOM   5666 C  CA  . CYS   B 2 235 ? 31.53634 6.32315   48.52361  1.000 76.00796  ? 506 CYS   B CA  1 
ATOM   5667 C  C   . CYS   B 2 235 ? 30.37345 5.39233   48.20939  1.000 73.28530  ? 506 CYS   B C   1 
ATOM   5668 O  O   . CYS   B 2 235 ? 30.49351 4.49586   47.36133  1.000 78.90660  ? 506 CYS   B O   1 
ATOM   5669 C  CB  . CYS   B 2 235 ? 31.80148 7.24900   47.33694  1.000 74.02804  ? 506 CYS   B CB  1 
ATOM   5670 S  SG  . CYS   B 2 235 ? 30.31420 8.07309   46.71820  1.000 77.13483  ? 506 CYS   B SG  1 
ATOM   5671 N  N   . GLU   B 2 236 ? 29.25510 5.60912   48.90932  1.000 70.00148  ? 507 GLU   B N   1 
ATOM   5672 C  CA  . GLU   B 2 236 ? 28.02542 4.87898   48.62268  1.000 79.11376  ? 507 GLU   B CA  1 
ATOM   5673 C  C   . GLU   B 2 236 ? 27.42402 5.31598   47.29395  1.000 74.20329  ? 507 GLU   B C   1 
ATOM   5674 O  O   . GLU   B 2 236 ? 26.87077 4.49302   46.55543  1.000 78.40766  ? 507 GLU   B O   1 
ATOM   5675 C  CB  . GLU   B 2 236 ? 27.01625 5.09050   49.75216  1.000 88.13067  ? 507 GLU   B CB  1 
ATOM   5676 C  CG  . GLU   B 2 236 ? 27.41881 4.50065   51.09285  1.000 95.51817  ? 507 GLU   B CG  1 
ATOM   5677 C  CD  . GLU   B 2 236 ? 26.69851 3.20094   51.39196  1.000 115.24095 ? 507 GLU   B CD  1 
ATOM   5678 O  OE1 . GLU   B 2 236 ? 26.43718 2.43271   50.44242  1.000 104.90606 ? 507 GLU   B OE1 1 
ATOM   5679 O  OE2 . GLU   B 2 236 ? 26.38306 2.95305   52.57511  1.000 133.06237 ? 507 GLU   B OE2 1 
ATOM   5680 N  N   . ASN   B 2 237 ? 27.51153 6.61032   46.97930  1.000 67.01772  ? 508 ASN   B N   1 
ATOM   5681 C  CA  . ASN   B 2 237 ? 26.96108 7.10740   45.72287  1.000 67.70486  ? 508 ASN   B CA  1 
ATOM   5682 C  C   . ASN   B 2 237 ? 27.75676 6.58015   44.53508  1.000 71.83115  ? 508 ASN   B C   1 
ATOM   5683 O  O   . ASN   B 2 237 ? 27.18019 6.11632   43.54444  1.000 72.08694  ? 508 ASN   B O   1 
ATOM   5684 C  CB  . ASN   B 2 237 ? 26.93986 8.63643   45.72985  1.000 70.95117  ? 508 ASN   B CB  1 
ATOM   5685 C  CG  . ASN   B 2 237 ? 26.04619 9.21194   44.65027  1.000 76.57432  ? 508 ASN   B CG  1 
ATOM   5686 O  OD1 . ASN   B 2 237 ? 25.07383 8.58279   44.23308  1.000 85.33947  ? 508 ASN   B OD1 1 
ATOM   5687 N  ND2 . ASN   B 2 237 ? 26.37110 10.41521  44.19182  1.000 68.62748  ? 508 ASN   B ND2 1 
ATOM   5688 N  N   . CYS   B 2 238 ? 29.08744 6.64408   44.61657  1.000 74.12602  ? 509 CYS   B N   1 
ATOM   5689 C  CA  . CYS   B 2 238 ? 29.93429 6.03472   43.59941  1.000 71.86874  ? 509 CYS   B CA  1 
ATOM   5690 C  C   . CYS   B 2 238 ? 30.04315 4.52548   43.76106  1.000 69.33184  ? 509 CYS   B C   1 
ATOM   5691 O  O   . CYS   B 2 238 ? 30.47012 3.84693   42.81999  1.000 63.84658  ? 509 CYS   B O   1 
ATOM   5692 C  CB  . CYS   B 2 238 ? 31.33881 6.64502   43.63437  1.000 74.46817  ? 509 CYS   B CB  1 
ATOM   5693 S  SG  . CYS   B 2 238 ? 31.45152 8.36653   43.09642  1.000 68.63964  ? 509 CYS   B SG  1 
ATOM   5694 N  N   . HIS   B 2 239 ? 29.66612 3.99296   44.92680  1.000 73.78561  ? 510 HIS   B N   1 
ATOM   5695 C  CA  . HIS   B 2 239 ? 29.82312 2.57181   45.24017  1.000 70.12695  ? 510 HIS   B CA  1 
ATOM   5696 C  C   . HIS   B 2 239 ? 31.27324 2.12976   45.06342  1.000 68.33522  ? 510 HIS   B C   1 
ATOM   5697 O  O   . HIS   B 2 239 ? 31.54729 1.02319   44.59438  1.000 72.73723  ? 510 HIS   B O   1 
ATOM   5698 C  CB  . HIS   B 2 239 ? 28.89412 1.70139   44.38695  1.000 62.30598  ? 510 HIS   B CB  1 
ATOM   5699 C  CG  . HIS   B 2 239 ? 27.45250 2.09912   44.45110  1.000 66.73172  ? 510 HIS   B CG  1 
ATOM   5700 N  ND1 . HIS   B 2 239 ? 26.53201 1.43724   45.23489  1.000 70.62578  ? 510 HIS   B ND1 1 
ATOM   5701 C  CD2 . HIS   B 2 239 ? 26.76943 3.08154   43.81738  1.000 69.17446  ? 510 HIS   B CD2 1 
ATOM   5702 C  CE1 . HIS   B 2 239 ? 25.34578 1.99978   45.08760  1.000 76.96301  ? 510 HIS   B CE1 1 
ATOM   5703 N  NE2 . HIS   B 2 239 ? 25.46260 3.00034   44.23325  1.000 77.34764  ? 510 HIS   B NE2 1 
ATOM   5704 N  N   . HIS   B 2 240 ? 32.21593 2.99414   45.43642  1.000 70.11984  ? 511 HIS   B N   1 
ATOM   5705 C  CA  . HIS   B 2 240 ? 33.59689 2.73401   45.04485  1.000 72.72762  ? 511 HIS   B CA  1 
ATOM   5706 C  C   . HIS   B 2 240 ? 34.55806 3.48445   45.95551  1.000 78.90189  ? 511 HIS   B C   1 
ATOM   5707 O  O   . HIS   B 2 240 ? 34.18176 4.43683   46.64065  1.000 77.78520  ? 511 HIS   B O   1 
ATOM   5708 C  CB  . HIS   B 2 240 ? 33.83273 3.12625   43.58034  1.000 68.90083  ? 511 HIS   B CB  1 
ATOM   5709 C  CG  . HIS   B 2 240 ? 35.10929 2.59544   43.00579  1.000 74.25790  ? 511 HIS   B CG  1 
ATOM   5710 N  ND1 . HIS   B 2 240 ? 35.83874 3.27932   42.05716  1.000 75.31370  ? 511 HIS   B ND1 1 
ATOM   5711 C  CD2 . HIS   B 2 240 ? 35.78209 1.44378   43.23906  1.000 78.51897  ? 511 HIS   B CD2 1 
ATOM   5712 C  CE1 . HIS   B 2 240 ? 36.90857 2.57465   41.73472  1.000 75.72617  ? 511 HIS   B CE1 1 
ATOM   5713 N  NE2 . HIS   B 2 240 ? 36.89780 1.45638   42.43752  1.000 81.57959  ? 511 HIS   B NE2 1 
ATOM   5714 N  N   . TYR   B 2 241 ? 35.81231 3.03474   45.94783  1.000 81.86632  ? 512 TYR   B N   1 
ATOM   5715 C  CA  . TYR   B 2 241 ? 36.87553 3.70920   46.68373  1.000 80.22245  ? 512 TYR   B CA  1 
ATOM   5716 C  C   . TYR   B 2 241 ? 37.26923 4.99446   45.96527  1.000 78.96317  ? 512 TYR   B C   1 
ATOM   5717 O  O   . TYR   B 2 241 ? 37.70672 4.95881   44.81014  1.000 82.81546  ? 512 TYR   B O   1 
ATOM   5718 C  CB  . TYR   B 2 241 ? 38.08300 2.78610   46.82694  1.000 80.85576  ? 512 TYR   B CB  1 
ATOM   5719 C  CG  . TYR   B 2 241 ? 38.07636 1.94122   48.07987  1.000 82.66817  ? 512 TYR   B CG  1 
ATOM   5720 C  CD1 . TYR   B 2 241 ? 36.95109 1.21600   48.44891  1.000 82.71212  ? 512 TYR   B CD1 1 
ATOM   5721 C  CD2 . TYR   B 2 241 ? 39.20342 1.85793   48.88678  1.000 88.63503  ? 512 TYR   B CD2 1 
ATOM   5722 C  CE1 . TYR   B 2 241 ? 36.94552 0.44029   49.59376  1.000 85.50591  ? 512 TYR   B CE1 1 
ATOM   5723 C  CE2 . TYR   B 2 241 ? 39.20809 1.08449   50.03109  1.000 94.15878  ? 512 TYR   B CE2 1 
ATOM   5724 C  CZ  . TYR   B 2 241 ? 38.07710 0.37792   50.37997  1.000 94.17648  ? 512 TYR   B CZ  1 
ATOM   5725 O  OH  . TYR   B 2 241 ? 38.07808 -0.39344  51.51954  1.000 104.16502 ? 512 TYR   B OH  1 
ATOM   5726 N  N   . THR   B 2 242 ? 37.11077 6.12866   46.64508  1.000 77.30414  ? 513 THR   B N   1 
ATOM   5727 C  CA  . THR   B 2 242 ? 37.41391 7.44191   46.10143  1.000 77.96297  ? 513 THR   B CA  1 
ATOM   5728 C  C   . THR   B 2 242 ? 38.21729 8.23201   47.12729  1.000 75.27141  ? 513 THR   B C   1 
ATOM   5729 O  O   . THR   B 2 242 ? 38.44043 7.78536   48.25731  1.000 79.26794  ? 513 THR   B O   1 
ATOM   5730 C  CB  . THR   B 2 242 ? 36.13366 8.21248   45.74170  1.000 74.70162  ? 513 THR   B CB  1 
ATOM   5731 O  OG1 . THR   B 2 242 ? 35.47263 8.62725   46.94497  1.000 80.03157  ? 513 THR   B OG1 1 
ATOM   5732 C  CG2 . THR   B 2 242 ? 35.17961 7.34056   44.93485  1.000 64.63358  ? 513 THR   B CG2 1 
ATOM   5733 N  N   . GLU   B 2 243 ? 38.64863 9.42301   46.72183  1.000 67.22406  ? 514 GLU   B N   1 
ATOM   5734 C  CA  . GLU   B 2 243 ? 39.31126 10.35671  47.61979  1.000 75.83358  ? 514 GLU   B CA  1 
ATOM   5735 C  C   . GLU   B 2 243 ? 38.27253 11.20076  48.34908  1.000 73.42715  ? 514 GLU   B C   1 
ATOM   5736 O  O   . GLU   B 2 243 ? 37.16270 11.41667  47.85419  1.000 68.27147  ? 514 GLU   B O   1 
ATOM   5737 C  CB  . GLU   B 2 243 ? 40.27151 11.26375  46.84874  1.000 81.26461  ? 514 GLU   B CB  1 
ATOM   5738 C  CG  . GLU   B 2 243 ? 41.31054 10.51880  46.02856  1.000 76.78235  ? 514 GLU   B CG  1 
ATOM   5739 C  CD  . GLU   B 2 243 ? 42.28652 11.45199  45.33778  1.000 76.16381  ? 514 GLU   B CD  1 
ATOM   5740 O  OE1 . GLU   B 2 243 ? 42.14619 12.68426  45.48924  1.000 73.31341  ? 514 GLU   B OE1 1 
ATOM   5741 O  OE2 . GLU   B 2 243 ? 43.19631 10.95245  44.64467  1.000 71.59030  ? 514 GLU   B OE2 1 
ATOM   5742 N  N   . ALA   B 2 244 ? 38.64042 11.68294  49.53524  1.000 72.10300  ? 515 ALA   B N   1 
ATOM   5743 C  CA  . ALA   B 2 244 ? 37.70965 12.44560  50.35657  1.000 66.10183  ? 515 ALA   B CA  1 
ATOM   5744 C  C   . ALA   B 2 244 ? 38.42747 13.61161  51.01947  1.000 70.55464  ? 515 ALA   B C   1 
ATOM   5745 O  O   . ALA   B 2 244 ? 39.65484 13.71272  50.99641  1.000 76.70798  ? 515 ALA   B O   1 
ATOM   5746 C  CB  . ALA   B 2 244 ? 37.04311 11.56364  51.41831  1.000 66.83784  ? 515 ALA   B CB  1 
ATOM   5747 N  N   . GLU   B 2 245 ? 37.63813 14.48646  51.64100  1.000 66.72157  ? 516 GLU   B N   1 
ATOM   5748 C  CA  . GLU   B 2 245 ? 38.15584 15.67684  52.31603  1.000 69.39508  ? 516 GLU   B CA  1 
ATOM   5749 C  C   . GLU   B 2 245 ? 37.40940 15.83866  53.63686  1.000 71.55249  ? 516 GLU   B C   1 
ATOM   5750 O  O   . GLU   B 2 245 ? 36.26017 16.28853  53.65046  1.000 68.52946  ? 516 GLU   B O   1 
ATOM   5751 C  CB  . GLU   B 2 245 ? 37.99757 16.91449  51.44054  1.000 74.63429  ? 516 GLU   B CB  1 
ATOM   5752 C  CG  . GLU   B 2 245 ? 38.87246 16.93551  50.20085  1.000 71.41052  ? 516 GLU   B CG  1 
ATOM   5753 C  CD  . GLU   B 2 245 ? 38.66624 18.18906  49.37344  1.000 74.82265  ? 516 GLU   B CD  1 
ATOM   5754 O  OE1 . GLU   B 2 245 ? 37.62483 18.85716  49.55016  1.000 66.38080  ? 516 GLU   B OE1 1 
ATOM   5755 O  OE2 . GLU   B 2 245 ? 39.54718 18.51027  48.55013  1.000 81.37571  ? 516 GLU   B OE2 1 
ATOM   5756 N  N   . ARG   B 2 246 ? 38.05705 15.46964  54.74099  1.000 79.04769  ? 517 ARG   B N   1 
ATOM   5757 C  CA  . ARG   B 2 246 ? 37.48064 15.66816  56.06607  1.000 83.07843  ? 517 ARG   B CA  1 
ATOM   5758 C  C   . ARG   B 2 246 ? 37.70836 17.11764  56.47655  1.000 86.00742  ? 517 ARG   B C   1 
ATOM   5759 O  O   . ARG   B 2 246 ? 38.84781 17.53268  56.71686  1.000 91.18376  ? 517 ARG   B O   1 
ATOM   5760 C  CB  . ARG   B 2 246 ? 38.09883 14.70611  57.07673  1.000 87.72252  ? 517 ARG   B CB  1 
ATOM   5761 C  CG  . ARG   B 2 246 ? 38.90421 13.58131  56.45317  1.000 84.05602  ? 517 ARG   B CG  1 
ATOM   5762 C  CD  . ARG   B 2 246 ? 39.30996 12.54203  57.48407  1.000 92.46900  ? 517 ARG   B CD  1 
ATOM   5763 N  NE  . ARG   B 2 246 ? 38.16946 11.75026  57.92872  1.000 106.04512 ? 517 ARG   B NE  1 
ATOM   5764 C  CZ  . ARG   B 2 246 ? 38.26389 10.61677  58.61019  1.000 119.63727 ? 517 ARG   B CZ  1 
ATOM   5765 N  NH1 . ARG   B 2 246 ? 39.43822 10.10398  58.93954  1.000 129.26998 ? 517 ARG   B NH1 1 
ATOM   5766 N  NH2 . ARG   B 2 246 ? 37.15219 9.97889   58.96559  1.000 115.43906 ? 517 ARG   B NH2 1 
ATOM   5767 N  N   . SER   B 2 247 ? 36.62804 17.89054  56.55125  1.000 82.32430  ? 518 SER   B N   1 
ATOM   5768 C  CA  . SER   B 2 247 ? 36.69929 19.30358  56.88541  1.000 83.21347  ? 518 SER   B CA  1 
ATOM   5769 C  C   . SER   B 2 247 ? 35.69667 19.62550  57.98274  1.000 83.66885  ? 518 SER   B C   1 
ATOM   5770 O  O   . SER   B 2 247 ? 34.64708 18.98622  58.09705  1.000 85.86394  ? 518 SER   B O   1 
ATOM   5771 C  CB  . SER   B 2 247 ? 36.42863 20.18508  55.65795  1.000 83.26061  ? 518 SER   B CB  1 
ATOM   5772 O  OG  . SER   B 2 247 ? 35.17258 19.87945  55.07747  1.000 89.04359  ? 518 SER   B OG  1 
ATOM   5773 N  N   . LEU   B 2 248 ? 36.03511 20.62443  58.79103  1.000 79.24637  ? 519 LEU   B N   1 
ATOM   5774 C  CA  . LEU   B 2 248 ? 35.16782 21.11299  59.85002  1.000 77.86205  ? 519 LEU   B CA  1 
ATOM   5775 C  C   . LEU   B 2 248 ? 34.60173 22.47236  59.46228  1.000 73.49082  ? 519 LEU   B C   1 
ATOM   5776 O  O   . LEU   B 2 248 ? 35.23958 23.24713  58.74367  1.000 74.29283  ? 519 LEU   B O   1 
ATOM   5777 C  CB  . LEU   B 2 248 ? 35.92230 21.21672  61.17870  1.000 80.02977  ? 519 LEU   B CB  1 
ATOM   5778 C  CG  . LEU   B 2 248 ? 36.59683 19.93064  61.66119  1.000 90.24479  ? 519 LEU   B CG  1 
ATOM   5779 C  CD1 . LEU   B 2 248 ? 37.21821 20.12759  63.03612  1.000 97.21199  ? 519 LEU   B CD1 1 
ATOM   5780 C  CD2 . LEU   B 2 248 ? 35.60783 18.77433  61.67304  1.000 85.46209  ? 519 LEU   B CD2 1 
ATOM   5781 N  N   . LEU   B 2 249 ? 33.39401 22.75585  59.94407  1.000 73.14835  ? 520 LEU   B N   1 
ATOM   5782 C  CA  . LEU   B 2 249 ? 32.70411 23.98372  59.58023  1.000 79.07228  ? 520 LEU   B CA  1 
ATOM   5783 C  C   . LEU   B 2 249 ? 31.86451 24.46484  60.75362  1.000 84.86357  ? 520 LEU   B C   1 
ATOM   5784 O  O   . LEU   B 2 249 ? 31.57437 23.71333  61.68772  1.000 87.07011  ? 520 LEU   B O   1 
ATOM   5785 C  CB  . LEU   B 2 249 ? 31.82593 23.78375  58.34103  1.000 82.42607  ? 520 LEU   B CB  1 
ATOM   5786 C  CG  . LEU   B 2 249 ? 32.50712 23.87931  56.97678  1.000 89.65828  ? 520 LEU   B CG  1 
ATOM   5787 C  CD1 . LEU   B 2 249 ? 31.54127 23.47833  55.87624  1.000 88.83318  ? 520 LEU   B CD1 1 
ATOM   5788 C  CD2 . LEU   B 2 249 ? 33.02783 25.28889  56.74671  1.000 92.50942  ? 520 LEU   B CD2 1 
ATOM   5789 N  N   . PHE   B 2 250 ? 31.47080 25.73465  60.68709  1.000 85.10906  ? 521 PHE   B N   1 
ATOM   5790 C  CA  . PHE   B 2 250 ? 30.68000 26.37970  61.72787  1.000 83.53457  ? 521 PHE   B CA  1 
ATOM   5791 C  C   . PHE   B 2 250 ? 29.31396 26.73526  61.15988  1.000 82.14213  ? 521 PHE   B C   1 
ATOM   5792 O  O   . PHE   B 2 250 ? 29.22253 27.46434  60.16626  1.000 86.89115  ? 521 PHE   B O   1 
ATOM   5793 C  CB  . PHE   B 2 250 ? 31.38637 27.62930  62.25650  1.000 89.68003  ? 521 PHE   B CB  1 
ATOM   5794 C  CG  . PHE   B 2 250 ? 32.70597 27.34728  62.91738  1.000 90.51054  ? 521 PHE   B CG  1 
ATOM   5795 C  CD1 . PHE   B 2 250 ? 32.75682 26.73874  64.16049  1.000 93.40103  ? 521 PHE   B CD1 1 
ATOM   5796 C  CD2 . PHE   B 2 250 ? 33.89495 27.69919  62.30045  1.000 85.82077  ? 521 PHE   B CD2 1 
ATOM   5797 C  CE1 . PHE   B 2 250 ? 33.96893 26.47950  64.77234  1.000 88.47142  ? 521 PHE   B CE1 1 
ATOM   5798 C  CE2 . PHE   B 2 250 ? 35.11011 27.44330  62.90709  1.000 80.25058  ? 521 PHE   B CE2 1 
ATOM   5799 C  CZ  . PHE   B 2 250 ? 35.14687 26.83286  64.14483  1.000 83.87702  ? 521 PHE   B CZ  1 
ATOM   5800 N  N   . ASP   B 2 251 ? 28.25661 26.22679  61.79411  1.000 80.96956  ? 522 ASP   B N   1 
ATOM   5801 C  CA  . ASP   B 2 251 ? 26.88810 26.44613  61.33534  1.000 85.64470  ? 522 ASP   B CA  1 
ATOM   5802 C  C   . ASP   B 2 251 ? 26.19586 27.56045  62.11325  1.000 87.75414  ? 522 ASP   B C   1 
ATOM   5803 O  O   . ASP   B 2 251 ? 25.80560 28.57856  61.53420  1.000 88.97295  ? 522 ASP   B O   1 
ATOM   5804 C  CB  . ASP   B 2 251 ? 26.08671 25.14203  61.44178  1.000 89.71130  ? 522 ASP   B CB  1 
ATOM   5805 C  CG  . ASP   B 2 251 ? 24.68476 25.27093  60.88264  1.000 90.66686  ? 522 ASP   B CG  1 
ATOM   5806 O  OD1 . ASP   B 2 251 ? 24.54823 25.60631  59.68736  1.000 86.90046  ? 522 ASP   B OD1 1 
ATOM   5807 O  OD2 . ASP   B 2 251 ? 23.71901 25.02776  61.63573  1.000 98.10083  ? 522 ASP   B OD2 1 
ATOM   5808 N  N   . LYS   B 2 252 ? 26.03212 27.38087  63.42219  1.000 89.26019  ? 523 LYS   B N   1 
ATOM   5809 C  CA  . LYS   B 2 252 ? 25.37564 28.35967  64.28073  1.000 92.38833  ? 523 LYS   B CA  1 
ATOM   5810 C  C   . LYS   B 2 252 ? 26.29885 28.66446  65.44947  1.000 83.03043  ? 523 LYS   B C   1 
ATOM   5811 O  O   . LYS   B 2 252 ? 26.66912 27.75872  66.20237  1.000 78.67665  ? 523 LYS   B O   1 
ATOM   5812 C  CB  . LYS   B 2 252 ? 24.01956 27.83918  64.76622  1.000 91.72999  ? 523 LYS   B CB  1 
ATOM   5813 C  CG  . LYS   B 2 252 ? 23.02878 27.60340  63.63387  1.000 97.05039  ? 523 LYS   B CG  1 
ATOM   5814 C  CD  . LYS   B 2 252 ? 21.90760 26.66164  64.03827  1.000 100.38982 ? 523 LYS   B CD  1 
ATOM   5815 C  CE  . LYS   B 2 252 ? 20.99785 26.36595  62.85431  1.000 93.67425  ? 523 LYS   B CE  1 
ATOM   5816 N  NZ  . LYS   B 2 252 ? 19.98887 25.31640  63.16450  1.000 92.79444  ? 523 LYS   B NZ  1 
ATOM   5817 N  N   . MET   B 2 253 ? 26.66853 29.93897  65.60104  1.000 84.07892  ? 524 MET   B N   1 
ATOM   5818 C  CA  . MET   B 2 253 ? 27.71034 30.26027  66.56182  1.000 79.08356  ? 524 MET   B CA  1 
ATOM   5819 C  C   . MET   B 2 253 ? 27.12191 30.80925  67.85685  1.000 82.97844  ? 524 MET   B C   1 
ATOM   5820 O  O   . MET   B 2 253 ? 26.07505 31.46479  67.84668  1.000 84.06694  ? 524 MET   B O   1 
ATOM   5821 C  CB  . MET   B 2 253 ? 28.68524 31.28298  65.97177  1.000 80.19269  ? 524 MET   B CB  1 
ATOM   5822 C  CG  . MET   B 2 253 ? 29.45535 30.76093  64.77477  1.000 87.27903  ? 524 MET   B CG  1 
ATOM   5823 S  SD  . MET   B 2 253 ? 30.24052 29.18071  65.14146  1.000 91.71045  ? 524 MET   B SD  1 
ATOM   5824 C  CE  . MET   B 2 253 ? 31.41400 29.66234  66.40471  1.000 83.62938  ? 524 MET   B CE  1 
ATOM   5825 N  N   . PRO   B 2 254 ? 27.78397 30.55294  68.99181  1.000 85.71644  ? 525 PRO   B N   1 
ATOM   5826 C  CA  . PRO   B 2 254 ? 27.28532 31.07279  70.27177  1.000 82.33961  ? 525 PRO   B CA  1 
ATOM   5827 C  C   . PRO   B 2 254 ? 27.52751 32.56439  70.42816  1.000 80.16659  ? 525 PRO   B C   1 
ATOM   5828 O  O   . PRO   B 2 254 ? 28.05230 33.21711  69.52029  1.000 85.57035  ? 525 PRO   B O   1 
ATOM   5829 C  CB  . PRO   B 2 254 ? 28.08067 30.26762  71.30533  1.000 84.01688  ? 525 PRO   B CB  1 
ATOM   5830 C  CG  . PRO   B 2 254 ? 29.35945 29.94814  70.60911  1.000 81.87506  ? 525 PRO   B CG  1 
ATOM   5831 C  CD  . PRO   B 2 254 ? 28.99177 29.72568  69.16450  1.000 86.64751  ? 525 PRO   B CD  1 
ATOM   5832 N  N   . GLU   B 2 255 ? 27.15193 33.11239  71.58508  1.000 79.20662  ? 526 GLU   B N   1 
ATOM   5833 C  CA  . GLU   B 2 255 ? 27.36765 34.53190  71.83648  1.000 85.74126  ? 526 GLU   B CA  1 
ATOM   5834 C  C   . GLU   B 2 255 ? 28.82287 34.83528  72.16951  1.000 79.84977  ? 526 GLU   B C   1 
ATOM   5835 O  O   . GLU   B 2 255 ? 29.30498 35.93583  71.87775  1.000 77.01678  ? 526 GLU   B O   1 
ATOM   5836 C  CB  . GLU   B 2 255 ? 26.45921 35.00971  72.97088  1.000 86.57419  ? 526 GLU   B CB  1 
ATOM   5837 C  CG  . GLU   B 2 255 ? 26.25635 36.51582  73.01555  1.000 94.23702  ? 526 GLU   B CG  1 
ATOM   5838 C  CD  . GLU   B 2 255 ? 25.37502 37.01636  71.88662  1.000 101.33061 ? 526 GLU   B CD  1 
ATOM   5839 O  OE1 . GLU   B 2 255 ? 24.52744 36.23607  71.40345  1.000 100.51492 ? 526 GLU   B OE1 1 
ATOM   5840 O  OE2 . GLU   B 2 255 ? 25.52979 38.18713  71.47998  1.000 98.71010  ? 526 GLU   B OE2 1 
ATOM   5841 N  N   . VAL   B 2 256 ? 29.53193 33.88355  72.77326  1.000 72.35783  ? 527 VAL   B N   1 
ATOM   5842 C  CA  . VAL   B 2 256 ? 30.93295 34.04689  73.14168  1.000 71.04567  ? 527 VAL   B CA  1 
ATOM   5843 C  C   . VAL   B 2 256 ? 31.70337 32.82524  72.66113  1.000 78.28732  ? 527 VAL   B C   1 
ATOM   5844 O  O   . VAL   B 2 256 ? 31.30257 31.68666  72.92696  1.000 83.28314  ? 527 VAL   B O   1 
ATOM   5845 C  CB  . VAL   B 2 256 ? 31.11082 34.23561  74.66114  1.000 75.54434  ? 527 VAL   B CB  1 
ATOM   5846 C  CG1 . VAL   B 2 256 ? 32.58788 34.24812  75.02731  1.000 72.11450  ? 527 VAL   B CG1 1 
ATOM   5847 C  CG2 . VAL   B 2 256 ? 30.43652 35.51917  75.12223  1.000 80.27016  ? 527 VAL   B CG2 1 
ATOM   5848 N  N   . ILE   B 2 257 ? 32.80378 33.06436  71.95656  1.000 80.46180  ? 528 ILE   B N   1 
ATOM   5849 C  CA  . ILE   B 2 257 ? 33.67662 32.01665  71.44643  1.000 76.57093  ? 528 ILE   B CA  1 
ATOM   5850 C  C   . ILE   B 2 257 ? 34.84533 31.86671  72.40862  1.000 71.46544  ? 528 ILE   B C   1 
ATOM   5851 O  O   . ILE   B 2 257 ? 35.55265 32.84237  72.69678  1.000 77.02729  ? 528 ILE   B O   1 
ATOM   5852 C  CB  . ILE   B 2 257 ? 34.17255 32.34335  70.02984  1.000 71.21595  ? 528 ILE   B CB  1 
ATOM   5853 C  CG1 . ILE   B 2 257 ? 32.99579 32.70992  69.12485  1.000 76.07161  ? 528 ILE   B CG1 1 
ATOM   5854 C  CG2 . ILE   B 2 257 ? 34.95496 31.17153  69.45565  1.000 70.46427  ? 528 ILE   B CG2 1 
ATOM   5855 C  CD1 . ILE   B 2 257 ? 33.41357 33.30687  67.80285  1.000 82.92966  ? 528 ILE   B CD1 1 
ATOM   5856 N  N   . THR   B 2 258 ? 35.03767 30.64899  72.90831  1.000 60.18833  ? 529 THR   B N   1 
ATOM   5857 C  CA  . THR   B 2 258 ? 36.17030 30.30019  73.75417  1.000 65.06717  ? 529 THR   B CA  1 
ATOM   5858 C  C   . THR   B 2 258 ? 37.21212 29.58246  72.90709  1.000 72.71792  ? 529 THR   B C   1 
ATOM   5859 O  O   . THR   B 2 258 ? 36.87602 28.66594  72.15020  1.000 79.45620  ? 529 THR   B O   1 
ATOM   5860 C  CB  . THR   B 2 258 ? 35.73043 29.41030  74.91913  1.000 66.52836  ? 529 THR   B CB  1 
ATOM   5861 O  OG1 . THR   B 2 258 ? 34.72304 30.08301  75.68556  1.000 65.76058  ? 529 THR   B OG1 1 
ATOM   5862 C  CG2 . THR   B 2 258 ? 36.91177 29.08201  75.82031  1.000 68.69428  ? 529 THR   B CG2 1 
ATOM   5863 N  N   . ILE   B 2 259 ? 38.46959 29.99848  73.03194  1.000 71.33926  ? 530 ILE   B N   1 
ATOM   5864 C  CA  . ILE   B 2 259 ? 39.56108 29.47365  72.22073  1.000 73.41428  ? 530 ILE   B CA  1 
ATOM   5865 C  C   . ILE   B 2 259 ? 40.63662 28.93755  73.15412  1.000 76.63170  ? 530 ILE   B C   1 
ATOM   5866 O  O   . ILE   B 2 259 ? 41.23173 29.69978  73.92865  1.000 76.09053  ? 530 ILE   B O   1 
ATOM   5867 C  CB  . ILE   B 2 259 ? 40.13852 30.54286  71.28065  1.000 70.74308  ? 530 ILE   B CB  1 
ATOM   5868 C  CG1 . ILE   B 2 259 ? 39.02704 31.16072  70.43065  1.000 66.43827  ? 530 ILE   B CG1 1 
ATOM   5869 C  CG2 . ILE   B 2 259 ? 41.21970 29.94283  70.39551  1.000 72.61015  ? 530 ILE   B CG2 1 
ATOM   5870 C  CD1 . ILE   B 2 259 ? 39.49498 32.29025  69.54302  1.000 75.73826  ? 530 ILE   B CD1 1 
ATOM   5871 N  N   . HIS   B 2 260 ? 40.87940 27.63064  73.07819  1.000 83.85456  ? 531 HIS   B N   1 
ATOM   5872 C  CA  . HIS   B 2 260 ? 41.94406 26.97592  73.82395  1.000 85.22799  ? 531 HIS   B CA  1 
ATOM   5873 C  C   . HIS   B 2 260 ? 43.20845 26.93139  72.97635  1.000 84.43368  ? 531 HIS   B C   1 
ATOM   5874 O  O   . HIS   B 2 260 ? 43.14900 26.71848  71.76201  1.000 86.97820  ? 531 HIS   B O   1 
ATOM   5875 C  CB  . HIS   B 2 260 ? 41.52104 25.56021  74.22444  1.000 86.49502  ? 531 HIS   B CB  1 
ATOM   5876 C  CG  . HIS   B 2 260 ? 42.58660 24.78064  74.93089  1.000 84.78728  ? 531 HIS   B CG  1 
ATOM   5877 N  ND1 . HIS   B 2 260 ? 42.77104 23.42910  74.73305  1.000 86.49526  ? 531 HIS   B ND1 1 
ATOM   5878 C  CD2 . HIS   B 2 260 ? 43.51515 25.15730  75.84172  1.000 83.46231  ? 531 HIS   B CD2 1 
ATOM   5879 C  CE1 . HIS   B 2 260 ? 43.77205 23.00835  75.48532  1.000 89.04046  ? 531 HIS   B CE1 1 
ATOM   5880 N  NE2 . HIS   B 2 260 ? 44.24107 24.03733  76.16781  1.000 83.78127  ? 531 HIS   B NE2 1 
ATOM   5881 N  N   . LEU   B 2 261 ? 44.35341 27.13703  73.62264  1.000 81.77869  ? 532 LEU   B N   1 
ATOM   5882 C  CA  . LEU   B 2 261 ? 45.64180 27.21837  72.94170  1.000 79.69791  ? 532 LEU   B CA  1 
ATOM   5883 C  C   . LEU   B 2 261 ? 46.52963 26.08255  73.43404  1.000 88.39547  ? 532 LEU   B C   1 
ATOM   5884 O  O   . LEU   B 2 261 ? 46.92628 26.06095  74.60430  1.000 94.16452  ? 532 LEU   B O   1 
ATOM   5885 C  CB  . LEU   B 2 261 ? 46.29696 28.57685  73.18570  1.000 78.58186  ? 532 LEU   B CB  1 
ATOM   5886 C  CG  . LEU   B 2 261 ? 45.39012 29.78994  72.96083  1.000 79.47303  ? 532 LEU   B CG  1 
ATOM   5887 C  CD1 . LEU   B 2 261 ? 46.13318 31.08630  73.24833  1.000 74.76755  ? 532 LEU   B CD1 1 
ATOM   5888 C  CD2 . LEU   B 2 261 ? 44.82463 29.79100  71.54739  1.000 72.92207  ? 532 LEU   B CD2 1 
ATOM   5889 N  N   . LYS   B 2 262 ? 46.84079 25.14460  72.54283  1.000 94.90220  ? 533 LYS   B N   1 
ATOM   5890 C  CA  . LYS   B 2 262 ? 47.70683 24.02936  72.89590  1.000 101.13591 ? 533 LYS   B CA  1 
ATOM   5891 C  C   . LYS   B 2 262 ? 49.15696 24.48741  73.01008  1.000 103.52224 ? 533 LYS   B C   1 
ATOM   5892 O  O   . LYS   B 2 262 ? 49.60610 25.39021  72.29960  1.000 101.14978 ? 533 LYS   B O   1 
ATOM   5893 C  CB  . LYS   B 2 262 ? 47.60149 22.91541  71.85358  1.000 96.56918  ? 533 LYS   B CB  1 
ATOM   5894 C  CG  . LYS   B 2 262 ? 46.20890 22.33528  71.67521  1.000 91.92022  ? 533 LYS   B CG  1 
ATOM   5895 C  CD  . LYS   B 2 262 ? 46.20536 21.28130  70.57725  1.000 97.38700  ? 533 LYS   B CD  1 
ATOM   5896 C  CE  . LYS   B 2 262 ? 44.82495 20.68050  70.38013  1.000 92.13498  ? 533 LYS   B CE  1 
ATOM   5897 N  NZ  . LYS   B 2 262 ? 44.80138 19.69132  69.26738  1.000 86.35338  ? 533 LYS   B NZ  1 
ATOM   5898 N  N   . CYS   B 2 263 ? 49.89206 23.84811  73.91447  1.000 104.24047 ? 534 CYS   B N   1 
ATOM   5899 C  CA  . CYS   B 2 263 ? 51.31177 24.13486  74.09377  1.000 97.62836  ? 534 CYS   B CA  1 
ATOM   5900 C  C   . CYS   B 2 263 ? 52.08618 22.86449  74.42872  1.000 100.28201 ? 534 CYS   B C   1 
ATOM   5901 O  O   . CYS   B 2 263 ? 52.35681 22.58052  75.59558  1.000 100.68468 ? 534 CYS   B O   1 
ATOM   5902 C  CB  . CYS   B 2 263 ? 51.52013 25.18166  75.19087  1.000 95.05696  ? 534 CYS   B CB  1 
ATOM   5903 S  SG  . CYS   B 2 263 ? 51.03508 26.86275  74.73295  1.000 96.40062  ? 534 CYS   B SG  1 
ATOM   5904 N  N   . LYS   B 2 280 ? 55.50290 22.87107  77.37896  1.000 99.07645  ? 551 LYS   B N   1 
ATOM   5905 C  CA  . LYS   B 2 280 ? 55.07858 24.24343  77.12990  1.000 112.08423 ? 551 LYS   B CA  1 
ATOM   5906 C  C   . LYS   B 2 280 ? 55.91896 24.88030  76.02571  1.000 116.87241 ? 551 LYS   B C   1 
ATOM   5907 O  O   . LYS   B 2 280 ? 57.08702 24.53641  75.84580  1.000 118.91455 ? 551 LYS   B O   1 
ATOM   5908 C  CB  . LYS   B 2 280 ? 55.17258 25.07630  78.41154  1.000 115.28902 ? 551 LYS   B CB  1 
ATOM   5909 C  CG  . LYS   B 2 280 ? 54.55431 26.46157  78.29787  1.000 115.74637 ? 551 LYS   B CG  1 
ATOM   5910 C  CD  . LYS   B 2 280 ? 54.95918 27.35672  79.45477  1.000 113.41723 ? 551 LYS   B CD  1 
ATOM   5911 C  CE  . LYS   B 2 280 ? 54.41791 28.76489  79.26547  1.000 110.53469 ? 551 LYS   B CE  1 
ATOM   5912 N  NZ  . LYS   B 2 280 ? 54.87343 29.69014  80.33849  1.000 115.33107 ? 551 LYS   B NZ  1 
ATOM   5913 N  N   . ILE   B 2 281 ? 55.31536 25.80733  75.28655  1.000 120.01690 ? 552 ILE   B N   1 
ATOM   5914 C  CA  . ILE   B 2 281 ? 55.98667 26.54004  74.21934  1.000 127.56911 ? 552 ILE   B CA  1 
ATOM   5915 C  C   . ILE   B 2 281 ? 55.97878 28.01615  74.58981  1.000 136.79478 ? 552 ILE   B C   1 
ATOM   5916 O  O   . ILE   B 2 281 ? 54.91027 28.60142  74.80570  1.000 138.50591 ? 552 ILE   B O   1 
ATOM   5917 C  CB  . ILE   B 2 281 ? 55.31253 26.31299  72.85729  1.000 128.24880 ? 552 ILE   B CB  1 
ATOM   5918 C  CG1 . ILE   B 2 281 ? 55.29641 24.82198  72.51267  1.000 121.39352 ? 552 ILE   B CG1 1 
ATOM   5919 C  CG2 . ILE   B 2 281 ? 56.02286 27.10830  71.77100  1.000 129.33748 ? 552 ILE   B CG2 1 
ATOM   5920 C  CD1 . ILE   B 2 281 ? 54.60363 24.50387  71.20524  1.000 109.95884 ? 552 ILE   B CD1 1 
ATOM   5921 N  N   . ASN   B 2 282 ? 57.16634 28.61620  74.66506  1.000 140.00572 ? 553 ASN   B N   1 
ATOM   5922 C  CA  . ASN   B 2 282 ? 57.31221 30.02718  74.99628  1.000 141.55441 ? 553 ASN   B CA  1 
ATOM   5923 C  C   . ASN   B 2 282 ? 57.28815 30.92992  73.76745  1.000 146.36588 ? 553 ASN   B C   1 
ATOM   5924 O  O   . ASN   B 2 282 ? 57.67790 32.10000  73.86207  1.000 142.62322 ? 553 ASN   B O   1 
ATOM   5925 C  CB  . ASN   B 2 282 ? 58.60288 30.25599  75.78709  1.000 132.06873 ? 553 ASN   B CB  1 
ATOM   5926 C  CG  . ASN   B 2 282 ? 58.41292 30.06931  77.27877  1.000 131.30649 ? 553 ASN   B CG  1 
ATOM   5927 O  OD1 . ASN   B 2 282 ? 57.96790 30.98045  77.97714  1.000 129.19798 ? 553 ASN   B OD1 1 
ATOM   5928 N  ND2 . ASN   B 2 282 ? 58.75734 28.88848  77.77696  1.000 124.85331 ? 553 ASN   B ND2 1 
ATOM   5929 N  N   . THR   B 2 283 ? 56.84163 30.41591  72.62167  1.000 149.50942 ? 554 THR   B N   1 
ATOM   5930 C  CA  . THR   B 2 283 ? 56.76199 31.21070  71.40617  1.000 149.42442 ? 554 THR   B CA  1 
ATOM   5931 C  C   . THR   B 2 283 ? 55.31670 31.61757  71.16819  1.000 145.80803 ? 554 THR   B C   1 
ATOM   5932 O  O   . THR   B 2 283 ? 54.50492 30.77113  70.76341  1.000 141.14258 ? 554 THR   B O   1 
ATOM   5933 C  CB  . THR   B 2 283 ? 57.29859 30.42724  70.20905  1.000 146.13033 ? 554 THR   B CB  1 
ATOM   5934 O  OG1 . THR   B 2 283 ? 58.67186 30.08551  70.43577  1.000 147.74700 ? 554 THR   B OG1 1 
ATOM   5935 C  CG2 . THR   B 2 283 ? 57.19303 31.25765  68.93630  1.000 140.50409 ? 554 THR   B CG2 1 
ATOM   5936 N  N   . PRO   B 2 284 ? 54.94574 32.87001  71.39995  1.000 149.55345 ? 555 PRO   B N   1 
ATOM   5937 C  CA  . PRO   B 2 284 ? 53.56135 33.30105  71.18943  1.000 145.58744 ? 555 PRO   B CA  1 
ATOM   5938 C  C   . PRO   B 2 284 ? 53.27360 33.50237  69.70461  1.000 137.42667 ? 555 PRO   B C   1 
ATOM   5939 O  O   . PRO   B 2 284 ? 54.13827 33.33836  68.84591  1.000 131.68537 ? 555 PRO   B O   1 
ATOM   5940 C  CB  . PRO   B 2 284 ? 53.48975 34.61970  71.96135  1.000 140.05125 ? 555 PRO   B CB  1 
ATOM   5941 C  CG  . PRO   B 2 284 ? 54.87824 35.15562  71.88832  1.000 143.80528 ? 555 PRO   B CG  1 
ATOM   5942 C  CD  . PRO   B 2 284 ? 55.78957 33.95593  71.92966  1.000 147.09909 ? 555 PRO   B CD  1 
ATOM   5943 N  N   . LEU   B 2 285 ? 52.02727 33.86814  69.41605  1.000 127.82252 ? 556 LEU   B N   1 
ATOM   5944 C  CA  . LEU   B 2 285 ? 51.55978 34.10213  68.05799  1.000 121.54988 ? 556 LEU   B CA  1 
ATOM   5945 C  C   . LEU   B 2 285 ? 50.86498 35.45762  67.99586  1.000 119.09523 ? 556 LEU   B C   1 
ATOM   5946 O  O   . LEU   B 2 285 ? 50.78594 36.18810  68.98841  1.000 111.02144 ? 556 LEU   B O   1 
ATOM   5947 C  CB  . LEU   B 2 285 ? 50.61561 32.98407  67.59685  1.000 120.17383 ? 556 LEU   B CB  1 
ATOM   5948 C  CG  . LEU   B 2 285 ? 51.17483 31.56020  67.56729  1.000 126.27663 ? 556 LEU   B CG  1 
ATOM   5949 C  CD1 . LEU   B 2 285 ? 50.12065 30.58662  67.06304  1.000 120.87407 ? 556 LEU   B CD1 1 
ATOM   5950 C  CD2 . LEU   B 2 285 ? 52.43058 31.48723  66.71196  1.000 121.09034 ? 556 LEU   B CD2 1 
ATOM   5951 N  N   . LEU   B 2 286 ? 50.35764 35.79415  66.81246  1.000 126.73315 ? 557 LEU   B N   1 
ATOM   5952 C  CA  . LEU   B 2 286 ? 49.61019 37.03055  66.63061  1.000 117.74169 ? 557 LEU   B CA  1 
ATOM   5953 C  C   . LEU   B 2 286 ? 48.20614 36.87728  67.20074  1.000 106.63331 ? 557 LEU   B C   1 
ATOM   5954 O  O   . LEU   B 2 286 ? 47.53113 35.87311  66.95288  1.000 101.68261 ? 557 LEU   B O   1 
ATOM   5955 C  CB  . LEU   B 2 286 ? 49.54373 37.40632  65.15052  1.000 114.51750 ? 557 LEU   B CB  1 
ATOM   5956 C  CG  . LEU   B 2 286 ? 50.36344 38.62469  64.71879  1.000 118.81803 ? 557 LEU   B CG  1 
ATOM   5957 C  CD1 . LEU   B 2 286 ? 51.84537 38.39754  64.96949  1.000 108.97510 ? 557 LEU   B CD1 1 
ATOM   5958 C  CD2 . LEU   B 2 286 ? 50.10697 38.95781  63.25601  1.000 123.52669 ? 557 LEU   B CD2 1 
ATOM   5959 N  N   . THR   B 2 287 ? 47.76764 37.87790  67.96560  1.000 102.64426 ? 558 THR   B N   1 
ATOM   5960 C  CA  . THR   B 2 287 ? 46.45589 37.87765  68.61170  1.000 100.05545 ? 558 THR   B CA  1 
ATOM   5961 C  C   . THR   B 2 287 ? 45.64647 39.04506  68.06232  1.000 103.43447 ? 558 THR   B C   1 
ATOM   5962 O  O   . THR   B 2 287 ? 45.75617 40.17787  68.55804  1.000 106.69828 ? 558 THR   B O   1 
ATOM   5963 C  CB  . THR   B 2 287 ? 46.59084 37.96855  70.13038  1.000 99.89939  ? 558 THR   B CB  1 
ATOM   5964 O  OG1 . THR   B 2 287 ? 47.56522 37.01969  70.58120  1.000 94.72081  ? 558 THR   B OG1 1 
ATOM   5965 C  CG2 . THR   B 2 287 ? 45.25934 37.66683  70.79936  1.000 96.14352  ? 558 THR   B CG2 1 
ATOM   5966 N  N   . PRO   B 2 288 ? 44.82452 38.81953  67.04032  1.000 97.47920  ? 559 PRO   B N   1 
ATOM   5967 C  CA  . PRO   B 2 288 ? 44.04487 39.92091  66.46769  1.000 96.02457  ? 559 PRO   B CA  1 
ATOM   5968 C  C   . PRO   B 2 288 ? 42.88719 40.32246  67.36673  1.000 92.49625  ? 559 PRO   B C   1 
ATOM   5969 O  O   . PRO   B 2 288 ? 42.27046 39.49262  68.03796  1.000 88.55073  ? 559 PRO   B O   1 
ATOM   5970 C  CB  . PRO   B 2 288 ? 43.54400 39.34412  65.13895  1.000 90.58083  ? 559 PRO   B CB  1 
ATOM   5971 C  CG  . PRO   B 2 288 ? 43.47984 37.87392  65.38074  1.000 82.58955  ? 559 PRO   B CG  1 
ATOM   5972 C  CD  . PRO   B 2 288 ? 44.62164 37.55630  66.31070  1.000 88.77266  ? 559 PRO   B CD  1 
ATOM   5973 N  N   . LEU   B 2 289 ? 42.59752 41.62294  67.37057  1.000 92.37026  ? 560 LEU   B N   1 
ATOM   5974 C  CA  . LEU   B 2 289 ? 41.49185 42.16385  68.15125  1.000 88.97492  ? 560 LEU   B CA  1 
ATOM   5975 C  C   . LEU   B 2 289 ? 40.15732 41.77173  67.52910  1.000 89.77257  ? 560 LEU   B C   1 
ATOM   5976 O  O   . LEU   B 2 289 ? 39.38391 41.01554  68.12605  1.000 85.56360  ? 560 LEU   B O   1 
ATOM   5977 C  CB  . LEU   B 2 289 ? 41.61091 43.68604  68.25644  1.000 91.12949  ? 560 LEU   B CB  1 
ATOM   5978 C  CG  . LEU   B 2 289 ? 42.85714 44.21666  68.96810  1.000 86.59542  ? 560 LEU   B CG  1 
ATOM   5979 C  CD1 . LEU   B 2 289 ? 43.10615 45.67089  68.60246  1.000 89.61678  ? 560 LEU   B CD1 1 
ATOM   5980 C  CD2 . LEU   B 2 289 ? 42.71823 44.06036  70.47459  1.000 82.67511  ? 560 LEU   B CD2 1 
ATOM   5981 N  N   . LYS   B 2 290 ? 39.88036 42.28349  66.33275  1.000 98.59741  ? 561 LYS   B N   1 
ATOM   5982 C  CA  . LYS   B 2 290 ? 38.67144 41.90974  65.61418  1.000 100.04165 ? 561 LYS   B CA  1 
ATOM   5983 C  C   . LYS   B 2 290 ? 38.81162 40.50160  65.04432  1.000 96.92279  ? 561 LYS   B C   1 
ATOM   5984 O  O   . LYS   B 2 290 ? 39.91488 40.03359  64.75047  1.000 92.29384  ? 561 LYS   B O   1 
ATOM   5985 C  CB  . LYS   B 2 290 ? 38.39199 42.90871  64.49011  1.000 104.12263 ? 561 LYS   B CB  1 
ATOM   5986 C  CG  . LYS   B 2 290 ? 37.00124 42.80940  63.88150  1.000 110.38688 ? 561 LYS   B CG  1 
ATOM   5987 C  CD  . LYS   B 2 290 ? 37.05526 42.95807  62.36924  1.000 122.30043 ? 561 LYS   B CD  1 
ATOM   5988 C  CE  . LYS   B 2 290 ? 35.66392 43.07226  61.76965  1.000 123.13574 ? 561 LYS   B CE  1 
ATOM   5989 N  NZ  . LYS   B 2 290 ? 35.01378 44.36274  62.12901  1.000 120.76507 ? 561 LYS   B NZ  1 
ATOM   5990 N  N   . LEU   B 2 291 ? 37.67721 39.82113  64.89013  1.000 98.27110  ? 562 LEU   B N   1 
ATOM   5991 C  CA  . LEU   B 2 291 ? 37.68026 38.45437  64.38969  1.000 93.81475  ? 562 LEU   B CA  1 
ATOM   5992 C  C   . LEU   B 2 291 ? 36.36009 38.15571  63.69494  1.000 91.04333  ? 562 LEU   B C   1 
ATOM   5993 O  O   . LEU   B 2 291 ? 35.29604 38.57590  64.15736  1.000 89.12163  ? 562 LEU   B O   1 
ATOM   5994 C  CB  . LEU   B 2 291 ? 37.91939 37.44837  65.52197  1.000 81.96761  ? 562 LEU   B CB  1 
ATOM   5995 C  CG  . LEU   B 2 291 ? 37.94193 35.97007  65.12872  1.000 77.95704  ? 562 LEU   B CG  1 
ATOM   5996 C  CD1 . LEU   B 2 291 ? 39.01188 35.70885  64.07932  1.000 78.38168  ? 562 LEU   B CD1 1 
ATOM   5997 C  CD2 . LEU   B 2 291 ? 38.15935 35.09375  66.35122  1.000 80.39096  ? 562 LEU   B CD2 1 
ATOM   5998 N  N   . SER   B 2 292 ? 36.44297 37.42849  62.58190  1.000 88.18623  ? 563 SER   B N   1 
ATOM   5999 C  CA  . SER   B 2 292 ? 35.27528 36.96041  61.85072  1.000 86.91654  ? 563 SER   B CA  1 
ATOM   6000 C  C   . SER   B 2 292 ? 35.55171 35.55507  61.33921  1.000 90.37363  ? 563 SER   B C   1 
ATOM   6001 O  O   . SER   B 2 292 ? 36.63085 35.28299  60.80549  1.000 93.19516  ? 563 SER   B O   1 
ATOM   6002 C  CB  . SER   B 2 292 ? 34.92762 37.89225  60.68217  1.000 95.80118  ? 563 SER   B CB  1 
ATOM   6003 O  OG  . SER   B 2 292 ? 33.75484 37.45817  60.01503  1.000 94.90076  ? 563 SER   B OG  1 
ATOM   6004 N  N   . LEU   B 2 293 ? 34.57387 34.66447  61.50707  1.000 93.70495  ? 564 LEU   B N   1 
ATOM   6005 C  CA  . LEU   B 2 293 ? 34.72019 33.26100  61.14542  1.000 96.06715  ? 564 LEU   B CA  1 
ATOM   6006 C  C   . LEU   B 2 293 ? 34.06553 32.92780  59.80942  1.000 96.88522  ? 564 LEU   B C   1 
ATOM   6007 O  O   . LEU   B 2 293 ? 33.72171 31.76550  59.56759  1.000 93.45623  ? 564 LEU   B O   1 
ATOM   6008 C  CB  . LEU   B 2 293 ? 34.14250 32.37119  62.24621  1.000 92.93181  ? 564 LEU   B CB  1 
ATOM   6009 C  CG  . LEU   B 2 293 ? 34.60124 32.65805  63.67619  1.000 81.38649  ? 564 LEU   B CG  1 
ATOM   6010 C  CD1 . LEU   B 2 293 ? 34.00080 31.64192  64.63147  1.000 77.06602  ? 564 LEU   B CD1 1 
ATOM   6011 C  CD2 . LEU   B 2 293 ? 36.11892 32.66055  63.77164  1.000 77.88092  ? 564 LEU   B CD2 1 
ATOM   6012 N  N   . GLU   B 2 294 ? 33.88931 33.92138  58.93628  1.000 99.40572  ? 565 GLU   B N   1 
ATOM   6013 C  CA  . GLU   B 2 294 ? 33.22387 33.68302  57.66143  1.000 99.92917  ? 565 GLU   B CA  1 
ATOM   6014 C  C   . GLU   B 2 294 ? 34.05965 32.82066  56.72302  1.000 102.50408 ? 565 GLU   B C   1 
ATOM   6015 O  O   . GLU   B 2 294 ? 33.50496 32.21288  55.80092  1.000 101.57155 ? 565 GLU   B O   1 
ATOM   6016 C  CB  . GLU   B 2 294 ? 32.88331 35.01955  56.99798  1.000 100.98380 ? 565 GLU   B CB  1 
ATOM   6017 C  CG  . GLU   B 2 294 ? 31.87454 34.92097  55.86620  1.000 104.01522 ? 565 GLU   B CG  1 
ATOM   6018 C  CD  . GLU   B 2 294 ? 31.26065 36.26158  55.51435  1.000 108.79135 ? 565 GLU   B CD  1 
ATOM   6019 O  OE1 . GLU   B 2 294 ? 31.45792 37.22669  56.28248  1.000 112.61699 ? 565 GLU   B OE1 1 
ATOM   6020 O  OE2 . GLU   B 2 294 ? 30.57917 36.35009  54.47125  1.000 108.97403 ? 565 GLU   B OE2 1 
ATOM   6021 N  N   . GLU   B 2 295 ? 35.37464 32.74312  56.94256  1.000 101.66877 ? 566 GLU   B N   1 
ATOM   6022 C  CA  . GLU   B 2 295 ? 36.22028 31.92030  56.08416  1.000 100.02556 ? 566 GLU   B CA  1 
ATOM   6023 C  C   . GLU   B 2 295 ? 35.96758 30.43285  56.30078  1.000 95.21549  ? 566 GLU   B C   1 
ATOM   6024 O  O   . GLU   B 2 295 ? 36.10073 29.64004  55.36137  1.000 106.12373 ? 566 GLU   B O   1 
ATOM   6025 C  CB  . GLU   B 2 295 ? 37.69366 32.25394  56.32775  1.000 101.15474 ? 566 GLU   B CB  1 
ATOM   6026 C  CG  . GLU   B 2 295 ? 38.66889 31.49000  55.44292  1.000 101.03123 ? 566 GLU   B CG  1 
ATOM   6027 C  CD  . GLU   B 2 295 ? 40.11448 31.86742  55.70433  1.000 105.77972 ? 566 GLU   B CD  1 
ATOM   6028 O  OE1 . GLU   B 2 295 ? 40.35067 32.88013  56.39657  1.000 104.86047 ? 566 GLU   B OE1 1 
ATOM   6029 O  OE2 . GLU   B 2 295 ? 41.01484 31.14970  55.21979  1.000 107.56823 ? 566 GLU   B OE2 1 
ATOM   6030 N  N   . TRP   B 2 296 ? 35.59523 30.03686  57.51497  1.000 84.78363  ? 567 TRP   B N   1 
ATOM   6031 C  CA  . TRP   B 2 296 ? 35.37448 28.63863  57.86270  1.000 87.05755  ? 567 TRP   B CA  1 
ATOM   6032 C  C   . TRP   B 2 296 ? 33.93326 28.40207  58.30029  1.000 86.69255  ? 567 TRP   B C   1 
ATOM   6033 O  O   . TRP   B 2 296 ? 33.66224 27.61316  59.20735  1.000 91.00274  ? 567 TRP   B O   1 
ATOM   6034 C  CB  . TRP   B 2 296 ? 36.34212 28.19264  58.95669  1.000 95.13693  ? 567 TRP   B CB  1 
ATOM   6035 C  CG  . TRP   B 2 296 ? 37.76177 28.61221  58.72238  1.000 97.97032  ? 567 TRP   B CG  1 
ATOM   6036 C  CD1 . TRP   B 2 296 ? 38.73353 27.89939  58.08208  1.000 94.00034  ? 567 TRP   B CD1 1 
ATOM   6037 C  CD2 . TRP   B 2 296 ? 38.37139 29.84274  59.13271  1.000 106.42236 ? 567 TRP   B CD2 1 
ATOM   6038 N  NE1 . TRP   B 2 296 ? 39.90936 28.61043  58.06622  1.000 93.59156  ? 567 TRP   B NE1 1 
ATOM   6039 C  CE2 . TRP   B 2 296 ? 39.71350 29.80694  58.70463  1.000 104.89318 ? 567 TRP   B CE2 1 
ATOM   6040 C  CE3 . TRP   B 2 296 ? 37.91199 30.97154  59.81909  1.000 102.41018 ? 567 TRP   B CE3 1 
ATOM   6041 C  CZ2 . TRP   B 2 296 ? 40.60069 30.85577  58.94057  1.000 106.75925 ? 567 TRP   B CZ2 1 
ATOM   6042 C  CZ3 . TRP   B 2 296 ? 38.79441 32.01193  60.05212  1.000 95.26472  ? 567 TRP   B CZ3 1 
ATOM   6043 C  CH2 . TRP   B 2 296 ? 40.12285 31.94670  59.61397  1.000 99.16089  ? 567 TRP   B CH2 1 
ATOM   6044 N  N   . SER   B 2 297 ? 32.98820 29.07856  57.65569  1.000 84.72312  ? 568 SER   B N   1 
ATOM   6045 C  CA  . SER   B 2 297 ? 31.58301 29.00214  58.02322  1.000 87.51078  ? 568 SER   B CA  1 
ATOM   6046 C  C   . SER   B 2 297 ? 30.78846 28.25473  56.95954  1.000 92.72353  ? 568 SER   B C   1 
ATOM   6047 O  O   . SER   B 2 297 ? 31.09716 28.32313  55.76635  1.000 95.50032  ? 568 SER   B O   1 
ATOM   6048 C  CB  . SER   B 2 297 ? 30.99289 30.40219  58.22140  1.000 86.37247  ? 568 SER   B CB  1 
ATOM   6049 O  OG  . SER   B 2 297 ? 29.62241 30.33445  58.57385  1.000 87.49735  ? 568 SER   B OG  1 
ATOM   6050 N  N   . THR   B 2 298 ? 29.75940 27.53215  57.40963  1.000 93.30967  ? 569 THR   B N   1 
ATOM   6051 C  CA  . THR   B 2 298 ? 28.84898 26.86811  56.48137  1.000 91.50639  ? 569 THR   B CA  1 
ATOM   6052 C  C   . THR   B 2 298 ? 28.11161 27.89100  55.62760  1.000 97.80231  ? 569 THR   B C   1 
ATOM   6053 O  O   . THR   B 2 298 ? 28.27121 27.93647  54.40246  1.000 100.64336 ? 569 THR   B O   1 
ATOM   6054 C  CB  . THR   B 2 298 ? 27.84674 26.00156  57.24840  1.000 90.91750  ? 569 THR   B CB  1 
ATOM   6055 O  OG1 . THR   B 2 298 ? 27.02402 26.83763  58.07189  1.000 97.56873  ? 569 THR   B OG1 1 
ATOM   6056 C  CG2 . THR   B 2 298 ? 28.56177 24.99300  58.12365  1.000 82.31833  ? 569 THR   B CG2 1 
ATOM   6057 N  N   . LYS   B 2 299 ? 27.28897 28.72114  56.26879  1.000 97.46103  ? 570 LYS   B N   1 
ATOM   6058 C  CA  . LYS   B 2 299 ? 26.56027 29.79336  55.61016  1.000 99.02691  ? 570 LYS   B CA  1 
ATOM   6059 C  C   . LYS   B 2 299 ? 27.29078 31.10167  55.87684  1.000 100.80350 ? 570 LYS   B C   1 
ATOM   6060 O  O   . LYS   B 2 299 ? 27.19165 31.64485  56.98795  1.000 105.21235 ? 570 LYS   B O   1 
ATOM   6061 C  CB  . LYS   B 2 299 ? 25.12108 29.85961  56.12664  1.000 103.66891 ? 570 LYS   B CB  1 
ATOM   6062 C  CG  . LYS   B 2 299 ? 24.36546 28.54533  55.99842  1.000 105.32954 ? 570 LYS   B CG  1 
ATOM   6063 C  CD  . LYS   B 2 299 ? 23.17379 28.49295  56.94039  1.000 112.93737 ? 570 LYS   B CD  1 
ATOM   6064 C  CE  . LYS   B 2 299 ? 23.62025 28.53008  58.39447  1.000 95.18688  ? 570 LYS   B CE  1 
ATOM   6065 N  NZ  . LYS   B 2 299 ? 22.47132 28.41848  59.33556  1.000 88.59212  ? 570 LYS   B NZ  1 
ATOM   6066 N  N   . PRO   B 2 300 ? 28.04336 31.64027  54.91016  1.000 99.75746  ? 571 PRO   B N   1 
ATOM   6067 C  CA  . PRO   B 2 300 ? 28.84513 32.84561  55.16958  1.000 102.13458 ? 571 PRO   B CA  1 
ATOM   6068 C  C   . PRO   B 2 300 ? 28.02358 34.03864  55.63387  1.000 105.58481 ? 571 PRO   B C   1 
ATOM   6069 O  O   . PRO   B 2 300 ? 27.32252 34.67256  54.83883  1.000 102.32259 ? 571 PRO   B O   1 
ATOM   6070 C  CB  . PRO   B 2 300 ? 29.50591 33.11964  53.81218  1.000 99.36206  ? 571 PRO   B CB  1 
ATOM   6071 C  CG  . PRO   B 2 300 ? 29.54529 31.78788  53.14000  1.000 99.18692  ? 571 PRO   B CG  1 
ATOM   6072 C  CD  . PRO   B 2 300 ? 28.28481 31.09323  53.56442  1.000 99.49553  ? 571 PRO   B CD  1 
ATOM   6073 N  N   . THR   B 2 301 ? 28.10859 34.34737  56.92608  1.000 110.72371 ? 572 THR   B N   1 
ATOM   6074 C  CA  . THR   B 2 301 ? 27.44205 35.49758  57.51630  1.000 111.25936 ? 572 THR   B CA  1 
ATOM   6075 C  C   . THR   B 2 301 ? 28.48146 36.44759  58.09669  1.000 106.47220 ? 572 THR   B C   1 
ATOM   6076 O  O   . THR   B 2 301 ? 29.58364 36.03492  58.47087  1.000 102.46331 ? 572 THR   B O   1 
ATOM   6077 C  CB  . THR   B 2 301 ? 26.45002 35.07425  58.60980  1.000 104.43666 ? 572 THR   B CB  1 
ATOM   6078 O  OG1 . THR   B 2 301 ? 25.91978 36.23841  59.25616  1.000 98.43355  ? 572 THR   B OG1 1 
ATOM   6079 C  CG2 . THR   B 2 301 ? 27.13425 34.19024  59.64205  1.000 97.43578  ? 572 THR   B CG2 1 
ATOM   6080 N  N   . ASN   B 2 302 ? 28.12056 37.72744  58.16879  1.000 109.12453 ? 573 ASN   B N   1 
ATOM   6081 C  CA  . ASN   B 2 302 ? 29.04041 38.77817  58.60628  1.000 107.47497 ? 573 ASN   B CA  1 
ATOM   6082 C  C   . ASN   B 2 302 ? 28.95329 39.05436  60.10011  1.000 101.01813 ? 573 ASN   B C   1 
ATOM   6083 O  O   . ASN   B 2 302 ? 29.09467 40.20257  60.53097  1.000 98.44228  ? 573 ASN   B O   1 
ATOM   6084 C  CB  . ASN   B 2 302 ? 28.78135 40.05080  57.80696  1.000 109.15621 ? 573 ASN   B CB  1 
ATOM   6085 C  CG  . ASN   B 2 302 ? 28.96350 39.84843  56.31659  1.000 116.98806 ? 573 ASN   B CG  1 
ATOM   6086 O  OD1 . ASN   B 2 302 ? 28.78804 38.74351  55.80313  1.000 114.33793 ? 573 ASN   B OD1 1 
ATOM   6087 N  ND2 . ASN   B 2 302 ? 29.32156 40.91645  55.61315  1.000 121.77476 ? 573 ASN   B ND2 1 
ATOM   6088 N  N   . ASP   B 2 303 ? 28.72341 38.02889  60.91594  1.000 100.73517 ? 574 ASP   B N   1 
ATOM   6089 C  CA  . ASP   B 2 303 ? 28.71820 38.18432  62.36892  1.000 95.15111  ? 574 ASP   B CA  1 
ATOM   6090 C  C   . ASP   B 2 303 ? 30.16161 38.17477  62.85504  1.000 91.87777  ? 574 ASP   B C   1 
ATOM   6091 O  O   . ASP   B 2 303 ? 30.77673 37.11545  62.99865  1.000 100.66242 ? 574 ASP   B O   1 
ATOM   6092 C  CB  . ASP   B 2 303 ? 27.89933 37.08065  63.02836  1.000 94.76457  ? 574 ASP   B CB  1 
ATOM   6093 C  CG  . ASP   B 2 303 ? 26.40753 37.34309  62.96286  1.000 87.88244  ? 574 ASP   B CG  1 
ATOM   6094 O  OD1 . ASP   B 2 303 ? 25.99792 38.50320  63.17717  1.000 87.70002  ? 574 ASP   B OD1 1 
ATOM   6095 O  OD2 . ASP   B 2 303 ? 25.64493 36.39053  62.69662  1.000 83.45124  ? 574 ASP   B OD2 1 
ATOM   6096 N  N   . SER   B 2 304 ? 30.70815 39.35960  63.10576  1.000 87.53744  ? 575 SER   B N   1 
ATOM   6097 C  CA  . SER   B 2 304 ? 32.08285 39.49457  63.56122  1.000 89.37621  ? 575 SER   B CA  1 
ATOM   6098 C  C   . SER   B 2 304 ? 32.14918 39.49174  65.08604  1.000 93.89535  ? 575 SER   B C   1 
ATOM   6099 O  O   . SER   B 2 304 ? 31.16331 39.75843  65.77820  1.000 93.22990  ? 575 SER   B O   1 
ATOM   6100 C  CB  . SER   B 2 304 ? 32.71109 40.77561  63.00999  1.000 91.60154  ? 575 SER   B CB  1 
ATOM   6101 O  OG  . SER   B 2 304 ? 31.99366 41.92035  63.43618  1.000 98.27091  ? 575 SER   B OG  1 
ATOM   6102 N  N   . TYR   B 2 305 ? 33.33802 39.18625  65.60426  1.000 95.57399  ? 576 TYR   B N   1 
ATOM   6103 C  CA  . TYR   B 2 305 ? 33.56432 39.07521  67.03706  1.000 95.94025  ? 576 TYR   B CA  1 
ATOM   6104 C  C   . TYR   B 2 305 ? 34.76804 39.91922  67.43694  1.000 92.86903  ? 576 TYR   B C   1 
ATOM   6105 O  O   . TYR   B 2 305 ? 35.59105 40.30381  66.60170  1.000 95.18328  ? 576 TYR   B O   1 
ATOM   6106 C  CB  . TYR   B 2 305 ? 33.77745 37.61195  67.45713  1.000 92.05790  ? 576 TYR   B CB  1 
ATOM   6107 C  CG  . TYR   B 2 305 ? 32.56393 36.74106  67.22407  1.000 90.42604  ? 576 TYR   B CG  1 
ATOM   6108 C  CD1 . TYR   B 2 305 ? 32.28919 36.22102  65.96623  1.000 93.81900  ? 576 TYR   B CD1 1 
ATOM   6109 C  CD2 . TYR   B 2 305 ? 31.68929 36.44536  68.25939  1.000 88.28589  ? 576 TYR   B CD2 1 
ATOM   6110 C  CE1 . TYR   B 2 305 ? 31.17702 35.43120  65.74553  1.000 88.07219  ? 576 TYR   B CE1 1 
ATOM   6111 C  CE2 . TYR   B 2 305 ? 30.57433 35.65748  68.04987  1.000 84.02459  ? 576 TYR   B CE2 1 
ATOM   6112 C  CZ  . TYR   B 2 305 ? 30.32362 35.15229  66.79121  1.000 86.66471  ? 576 TYR   B CZ  1 
ATOM   6113 O  OH  . TYR   B 2 305 ? 29.21479 34.36624  66.57910  1.000 99.46534  ? 576 TYR   B OH  1 
ATOM   6114 N  N   . GLY   B 2 306 ? 34.85936 40.21203  68.73345  1.000 86.36265  ? 577 GLY   B N   1 
ATOM   6115 C  CA  . GLY   B 2 306 ? 35.96215 41.00397  69.25006  1.000 83.74644  ? 577 GLY   B CA  1 
ATOM   6116 C  C   . GLY   B 2 306 ? 36.60005 40.42074  70.49646  1.000 82.62010  ? 577 GLY   B C   1 
ATOM   6117 O  O   . GLY   B 2 306 ? 35.89846 39.92504  71.38126  1.000 84.08408  ? 577 GLY   B O   1 
ATOM   6118 N  N   . LEU   B 2 307 ? 37.92792 40.47615  70.58262  1.000 82.25000  ? 578 LEU   B N   1 
ATOM   6119 C  CA  . LEU   B 2 307 ? 38.63325 39.93732  71.74020  1.000 81.66120  ? 578 LEU   B CA  1 
ATOM   6120 C  C   . LEU   B 2 307 ? 38.29736 40.74125  72.99022  1.000 75.88873  ? 578 LEU   B C   1 
ATOM   6121 O  O   . LEU   B 2 307 ? 38.35342 41.97501  72.98102  1.000 82.34258  ? 578 LEU   B O   1 
ATOM   6122 C  CB  . LEU   B 2 307 ? 40.14252 39.95148  71.49598  1.000 81.85319  ? 578 LEU   B CB  1 
ATOM   6123 C  CG  . LEU   B 2 307 ? 41.04229 39.52285  72.66043  1.000 79.26905  ? 578 LEU   B CG  1 
ATOM   6124 C  CD1 . LEU   B 2 307 ? 40.72749 38.10239  73.10580  1.000 83.73625  ? 578 LEU   B CD1 1 
ATOM   6125 C  CD2 . LEU   B 2 307 ? 42.51183 39.65671  72.28677  1.000 79.85433  ? 578 LEU   B CD2 1 
ATOM   6126 N  N   . PHE   B 2 308 ? 37.94490 40.04049  74.07078  1.000 72.86352  ? 579 PHE   B N   1 
ATOM   6127 C  CA  . PHE   B 2 308 ? 37.61691 40.71902  75.31986  1.000 79.17496  ? 579 PHE   B CA  1 
ATOM   6128 C  C   . PHE   B 2 308 ? 38.15704 40.04506  76.57293  1.000 80.82297  ? 579 PHE   B C   1 
ATOM   6129 O  O   . PHE   B 2 308 ? 38.00946 40.62458  77.65153  1.000 85.46181  ? 579 PHE   B O   1 
ATOM   6130 C  CB  . PHE   B 2 308 ? 36.09353 40.88138  75.46809  1.000 82.44323  ? 579 PHE   B CB  1 
ATOM   6131 C  CG  . PHE   B 2 308 ? 35.37722 39.61284  75.83742  1.000 79.99639  ? 579 PHE   B CG  1 
ATOM   6132 C  CD1 . PHE   B 2 308 ? 35.09111 38.66025  74.87521  1.000 79.27051  ? 579 PHE   B CD1 1 
ATOM   6133 C  CD2 . PHE   B 2 308 ? 34.97932 39.37810  77.14494  1.000 78.88481  ? 579 PHE   B CD2 1 
ATOM   6134 C  CE1 . PHE   B 2 308 ? 34.42975 37.49297  75.20937  1.000 78.23734  ? 579 PHE   B CE1 1 
ATOM   6135 C  CE2 . PHE   B 2 308 ? 34.31872 38.21267  77.48560  1.000 76.72858  ? 579 PHE   B CE2 1 
ATOM   6136 C  CZ  . PHE   B 2 308 ? 34.04341 37.26899  76.51613  1.000 75.66717  ? 579 PHE   B CZ  1 
ATOM   6137 N  N   . ALA   B 2 309 ? 38.77999 38.87109  76.48870  1.000 74.10757  ? 580 ALA   B N   1 
ATOM   6138 C  CA  . ALA   B 2 309 ? 39.30238 38.22711  77.68570  1.000 67.52869  ? 580 ALA   B CA  1 
ATOM   6139 C  C   . ALA   B 2 309 ? 40.45190 37.30551  77.30597  1.000 70.49972  ? 580 ALA   B C   1 
ATOM   6140 O  O   . ALA   B 2 309 ? 40.35739 36.55297  76.33093  1.000 76.76563  ? 580 ALA   B O   1 
ATOM   6141 C  CB  . ALA   B 2 309 ? 38.20807 37.44540  78.42120  1.000 69.19114  ? 580 ALA   B CB  1 
ATOM   6142 N  N   . VAL   B 2 310 ? 41.53116 37.37410  78.08564  1.000 69.45079  ? 581 VAL   B N   1 
ATOM   6143 C  CA  . VAL   B 2 310 ? 42.73301 36.57748  77.86192  1.000 71.41925  ? 581 VAL   B CA  1 
ATOM   6144 C  C   . VAL   B 2 310 ? 43.19201 35.99397  79.19243  1.000 72.63414  ? 581 VAL   B C   1 
ATOM   6145 O  O   . VAL   B 2 310 ? 43.34437 36.72150  80.18109  1.000 77.13617  ? 581 VAL   B O   1 
ATOM   6146 C  CB  . VAL   B 2 310 ? 43.86587 37.40654  77.22354  1.000 70.19939  ? 581 VAL   B CB  1 
ATOM   6147 C  CG1 . VAL   B 2 310 ? 45.12382 36.56480  77.08382  1.000 71.14545  ? 581 VAL   B CG1 1 
ATOM   6148 C  CG2 . VAL   B 2 310 ? 43.43489 37.95396  75.87033  1.000 72.98946  ? 581 VAL   B CG2 1 
ATOM   6149 N  N   . VAL   B 2 311 ? 43.41627 34.68269  79.21299  1.000 66.31470  ? 582 VAL   B N   1 
ATOM   6150 C  CA  . VAL   B 2 311 ? 43.98139 33.97906  80.35929  1.000 72.72849  ? 582 VAL   B CA  1 
ATOM   6151 C  C   . VAL   B 2 311 ? 45.38368 33.52889  79.97634  1.000 82.25418  ? 582 VAL   B C   1 
ATOM   6152 O  O   . VAL   B 2 311 ? 45.55926 32.78564  79.00140  1.000 85.14773  ? 582 VAL   B O   1 
ATOM   6153 C  CB  . VAL   B 2 311 ? 43.11482 32.78242  80.77909  1.000 72.06259  ? 582 VAL   B CB  1 
ATOM   6154 C  CG1 . VAL   B 2 311 ? 43.77707 32.02449  81.91950  1.000 76.39645  ? 582 VAL   B CG1 1 
ATOM   6155 C  CG2 . VAL   B 2 311 ? 41.72677 33.24795  81.17881  1.000 71.51616  ? 582 VAL   B CG2 1 
ATOM   6156 N  N   . MET   B 2 312 ? 46.37830 33.97205  80.74292  1.000 88.27149  ? 583 MET   B N   1 
ATOM   6157 C  CA  . MET   B 2 312 ? 47.77804 33.72481  80.44267  1.000 92.83448  ? 583 MET   B CA  1 
ATOM   6158 C  C   . MET   B 2 312 ? 48.41089 32.87336  81.53562  1.000 91.26978  ? 583 MET   B C   1 
ATOM   6159 O  O   . MET   B 2 312 ? 47.95820 32.85553  82.68454  1.000 89.24378  ? 583 MET   B O   1 
ATOM   6160 C  CB  . MET   B 2 312 ? 48.54764 35.04218  80.29397  1.000 94.33615  ? 583 MET   B CB  1 
ATOM   6161 C  CG  . MET   B 2 312 ? 47.70103 36.18401  79.75952  1.000 93.11089  ? 583 MET   B CG  1 
ATOM   6162 S  SD  . MET   B 2 312 ? 48.69464 37.56617  79.17755  1.000 122.65716 ? 583 MET   B SD  1 
ATOM   6163 C  CE  . MET   B 2 312 ? 49.53131 36.79874  77.79418  1.000 99.97567  ? 583 MET   B CE  1 
ATOM   6164 N  N   . HIS   B 2 313 ? 49.48012 32.17553  81.15946  1.000 96.14771  ? 584 HIS   B N   1 
ATOM   6165 C  CA  . HIS   B 2 313 ? 50.17856 31.24447  82.03466  1.000 99.86675  ? 584 HIS   B CA  1 
ATOM   6166 C  C   . HIS   B 2 313 ? 51.59534 31.74527  82.27410  1.000 101.64256 ? 584 HIS   B C   1 
ATOM   6167 O  O   . HIS   B 2 313 ? 52.29075 32.12640  81.32642  1.000 101.37661 ? 584 HIS   B O   1 
ATOM   6168 C  CB  . HIS   B 2 313 ? 50.20752 29.84100  81.42012  1.000 93.90918  ? 584 HIS   B CB  1 
ATOM   6169 C  CG  . HIS   B 2 313 ? 50.68736 28.77654  82.35689  1.000 103.57953 ? 584 HIS   B CG  1 
ATOM   6170 N  ND1 . HIS   B 2 313 ? 49.83317 27.88343  82.96700  1.000 113.01511 ? 584 HIS   B ND1 1 
ATOM   6171 C  CD2 . HIS   B 2 313 ? 51.93182 28.45982  82.78639  1.000 109.95333 ? 584 HIS   B CD2 1 
ATOM   6172 C  CE1 . HIS   B 2 313 ? 50.53033 27.06261  83.73207  1.000 111.69921 ? 584 HIS   B CE1 1 
ATOM   6173 N  NE2 . HIS   B 2 313 ? 51.80634 27.39119  83.64066  1.000 112.92047 ? 584 HIS   B NE2 1 
ATOM   6174 N  N   . SER   B 2 314 ? 52.02046 31.73978  83.53554  1.000 103.72063 ? 585 SER   B N   1 
ATOM   6175 C  CA  . SER   B 2 314 ? 53.36337 32.13984  83.92640  1.000 107.83951 ? 585 SER   B CA  1 
ATOM   6176 C  C   . SER   B 2 314 ? 54.06714 30.94280  84.54489  1.000 115.61186 ? 585 SER   B C   1 
ATOM   6177 O  O   . SER   B 2 314 ? 53.51967 30.29023  85.44176  1.000 115.49682 ? 585 SER   B O   1 
ATOM   6178 C  CB  . SER   B 2 314 ? 53.32704 33.30624  84.91748  1.000 103.44027 ? 585 SER   B CB  1 
ATOM   6179 O  OG  . SER   B 2 314 ? 52.60857 34.40527  84.38662  1.000 105.50702 ? 585 SER   B OG  1 
ATOM   6180 N  N   . GLY   B 2 315 ? 55.26742 30.66228  84.06825  1.000 122.54725 ? 586 GLY   B N   1 
ATOM   6181 C  CA  . GLY   B 2 315 ? 56.03135 29.51160  84.51513  1.000 122.33216 ? 586 GLY   B CA  1 
ATOM   6182 C  C   . GLY   B 2 315 ? 56.12457 28.47924  83.40649  1.000 126.52093 ? 586 GLY   B C   1 
ATOM   6183 O  O   . GLY   B 2 315 ? 55.17346 28.26462  82.64427  1.000 130.45952 ? 586 GLY   B O   1 
ATOM   6184 N  N   . ILE   B 2 316 ? 57.28619 27.83349  83.31058  1.000 128.16264 ? 587 ILE   B N   1 
ATOM   6185 C  CA  . ILE   B 2 316 ? 57.48605 26.81885  82.28235  1.000 128.93861 ? 587 ILE   B CA  1 
ATOM   6186 C  C   . ILE   B 2 316 ? 56.75538 25.53325  82.64569  1.000 128.33327 ? 587 ILE   B C   1 
ATOM   6187 O  O   . ILE   B 2 316 ? 56.18005 24.86576  81.77873  1.000 116.77215 ? 587 ILE   B O   1 
ATOM   6188 C  CB  . ILE   B 2 316 ? 58.99017 26.57588  82.06944  1.000 130.88442 ? 587 ILE   B CB  1 
ATOM   6189 C  CG1 . ILE   B 2 316 ? 59.72593 27.90838  81.91709  1.000 123.17961 ? 587 ILE   B CG1 1 
ATOM   6190 C  CG2 . ILE   B 2 316 ? 59.21999 25.69295  80.85148  1.000 123.88880 ? 587 ILE   B CG2 1 
ATOM   6191 C  CD1 . ILE   B 2 316 ? 61.22992 27.78680  82.01095  1.000 119.35048 ? 587 ILE   B CD1 1 
ATOM   6192 N  N   . THR   B 2 317 ? 56.76106 25.16961  83.92548  1.000 136.51249 ? 588 THR   B N   1 
ATOM   6193 C  CA  . THR   B 2 317 ? 56.11640 23.94452  84.37951  1.000 132.53892 ? 588 THR   B CA  1 
ATOM   6194 C  C   . THR   B 2 317 ? 54.63655 24.20631  84.63168  1.000 129.94886 ? 588 THR   B C   1 
ATOM   6195 O  O   . THR   B 2 317 ? 54.28064 25.01649  85.49466  1.000 129.36100 ? 588 THR   B O   1 
ATOM   6196 C  CB  . THR   B 2 317 ? 56.79116 23.42366  85.64673  1.000 132.92117 ? 588 THR   B CB  1 
ATOM   6197 O  OG1 . THR   B 2 317 ? 56.64981 24.38913  86.69671  1.000 135.22852 ? 588 THR   B OG1 1 
ATOM   6198 C  CG2 . THR   B 2 317 ? 58.27072 23.16914  85.39608  1.000 128.34102 ? 588 THR   B CG2 1 
ATOM   6199 N  N   . ILE   B 2 318 ? 53.77434 23.51986  83.87744  1.000 125.70136 ? 589 ILE   B N   1 
ATOM   6200 C  CA  . ILE   B 2 318 ? 52.33484 23.63036  84.08306  1.000 124.80094 ? 589 ILE   B CA  1 
ATOM   6201 C  C   . ILE   B 2 318 ? 51.88378 22.95047  85.36678  1.000 123.83356 ? 589 ILE   B C   1 
ATOM   6202 O  O   . ILE   B 2 318 ? 50.74721 23.16096  85.80693  1.000 118.55582 ? 589 ILE   B O   1 
ATOM   6203 C  CB  . ILE   B 2 318 ? 51.58794 23.05122  82.86251  1.000 116.99415 ? 589 ILE   B CB  1 
ATOM   6204 C  CG1 . ILE   B 2 318 ? 52.28151 23.48001  81.56807  1.000 113.33430 ? 589 ILE   B CG1 1 
ATOM   6205 C  CG2 . ILE   B 2 318 ? 50.13744 23.51471  82.83601  1.000 104.03998 ? 589 ILE   B CG2 1 
ATOM   6206 C  CD1 . ILE   B 2 318 ? 51.56793 23.02974  80.31096  1.000 96.72050  ? 589 ILE   B CD1 1 
ATOM   6207 N  N   . SER   B 2 319 ? 52.75486 22.15060  85.98847  1.000 127.03046 ? 590 SER   B N   1 
ATOM   6208 C  CA  . SER   B 2 319 ? 52.39340 21.48102  87.23396  1.000 126.80399 ? 590 SER   B CA  1 
ATOM   6209 C  C   . SER   B 2 319 ? 52.08310 22.48742  88.33519  1.000 123.38162 ? 590 SER   B C   1 
ATOM   6210 O  O   . SER   B 2 319 ? 51.18073 22.26664  89.15142  1.000 124.93984 ? 590 SER   B O   1 
ATOM   6211 C  CB  . SER   B 2 319 ? 53.51845 20.54159  87.66916  1.000 125.43144 ? 590 SER   B CB  1 
ATOM   6212 O  OG  . SER   B 2 319 ? 53.80673 19.58688  86.66253  1.000 127.38978 ? 590 SER   B OG  1 
ATOM   6213 N  N   . SER   B 2 320 ? 52.81507 23.59778  88.37358  1.000 117.40719 ? 591 SER   B N   1 
ATOM   6214 C  CA  . SER   B 2 320 ? 52.60966 24.63456  89.38076  1.000 112.16924 ? 591 SER   B CA  1 
ATOM   6215 C  C   . SER   B 2 320 ? 52.84358 26.01219  88.76791  1.000 111.04365 ? 591 SER   B C   1 
ATOM   6216 O  O   . SER   B 2 320 ? 53.55134 26.85576  89.31960  1.000 107.22216 ? 591 SER   B O   1 
ATOM   6217 C  CB  . SER   B 2 320 ? 53.51395 24.40770  90.59087  1.000 115.46274 ? 591 SER   B CB  1 
ATOM   6218 O  OG  . SER   B 2 320 ? 53.25638 25.36416  91.60436  1.000 115.30170 ? 591 SER   B OG  1 
ATOM   6219 N  N   . GLY   B 2 321 ? 52.24394 26.24902  87.60413  1.000 110.55315 ? 592 GLY   B N   1 
ATOM   6220 C  CA  . GLY   B 2 321 ? 52.29917 27.55354  86.97659  1.000 106.65066 ? 592 GLY   B CA  1 
ATOM   6221 C  C   . GLY   B 2 321 ? 51.16191 28.44644  87.44096  1.000 107.23859 ? 592 GLY   B C   1 
ATOM   6222 O  O   . GLY   B 2 321 ? 50.10243 27.97422  87.84378  1.000 110.13089 ? 592 GLY   B O   1 
ATOM   6223 N  N   . HIS   B 2 322 ? 51.39245 29.75485  87.38007  1.000 112.22464 ? 593 HIS   B N   1 
ATOM   6224 C  CA  . HIS   B 2 322 ? 50.43479 30.73278  87.88087  1.000 108.22027 ? 593 HIS   B CA  1 
ATOM   6225 C  C   . HIS   B 2 322 ? 49.61680 31.30096  86.72866  1.000 100.56841 ? 593 HIS   B C   1 
ATOM   6226 O  O   . HIS   B 2 322 ? 50.17658 31.77474  85.73600  1.000 97.92116  ? 593 HIS   B O   1 
ATOM   6227 C  CB  . HIS   B 2 322 ? 51.14508 31.86066  88.63095  1.000 107.15948 ? 593 HIS   B CB  1 
ATOM   6228 C  CG  . HIS   B 2 322 ? 50.21483 32.76949  89.37239  1.000 103.69763 ? 593 HIS   B CG  1 
ATOM   6229 N  ND1 . HIS   B 2 322 ? 49.70364 33.92417  88.82002  1.000 104.64362 ? 593 HIS   B ND1 1 
ATOM   6230 C  CD2 . HIS   B 2 322 ? 49.69931 32.69017  90.62203  1.000 101.88577 ? 593 HIS   B CD2 1 
ATOM   6231 C  CE1 . HIS   B 2 322 ? 48.91538 34.51823  89.69814  1.000 102.22046 ? 593 HIS   B CE1 1 
ATOM   6232 N  NE2 . HIS   B 2 322 ? 48.89541 33.78977  90.79975  1.000 105.21118 ? 593 HIS   B NE2 1 
ATOM   6233 N  N   . TYR   B 2 323 ? 48.29569 31.25603  86.86411  1.000 97.68151  ? 594 TYR   B N   1 
ATOM   6234 C  CA  . TYR   B 2 323 ? 47.40299 31.79446  85.84821  1.000 91.91806  ? 594 TYR   B CA  1 
ATOM   6235 C  C   . TYR   B 2 323 ? 47.04633 33.23657  86.18231  1.000 94.31803  ? 594 TYR   B C   1 
ATOM   6236 O  O   . TYR   B 2 323 ? 46.66468 33.54363  87.31635  1.000 99.62580  ? 594 TYR   B O   1 
ATOM   6237 C  CB  . TYR   B 2 323 ? 46.13531 30.94799  85.73412  1.000 86.62457  ? 594 TYR   B CB  1 
ATOM   6238 C  CG  . TYR   B 2 323 ? 46.35978 29.59353  85.10297  1.000 86.04591  ? 594 TYR   B CG  1 
ATOM   6239 C  CD1 . TYR   B 2 323 ? 46.69217 28.49125  85.87814  1.000 92.14500  ? 594 TYR   B CD1 1 
ATOM   6240 C  CD2 . TYR   B 2 323 ? 46.24035 29.41750  83.73083  1.000 86.65280  ? 594 TYR   B CD2 1 
ATOM   6241 C  CE1 . TYR   B 2 323 ? 46.89692 27.25004  85.30566  1.000 95.16181  ? 594 TYR   B CE1 1 
ATOM   6242 C  CE2 . TYR   B 2 323 ? 46.44532 28.18080  83.14846  1.000 95.40387  ? 594 TYR   B CE2 1 
ATOM   6243 C  CZ  . TYR   B 2 323 ? 46.77229 27.10036  83.94074  1.000 99.16675  ? 594 TYR   B CZ  1 
ATOM   6244 O  OH  . TYR   B 2 323 ? 46.97645 25.86632  83.36678  1.000 95.32737  ? 594 TYR   B OH  1 
ATOM   6245 N  N   . THR   B 2 324 ? 47.17788 34.11602  85.19400  1.000 93.55592  ? 595 THR   B N   1 
ATOM   6246 C  CA  . THR   B 2 324 ? 46.80714 35.51694  85.32715  1.000 97.33568  ? 595 THR   B CA  1 
ATOM   6247 C  C   . THR   B 2 324 ? 45.70418 35.83493  84.32841  1.000 93.70165  ? 595 THR   B C   1 
ATOM   6248 O  O   . THR   B 2 324 ? 45.67716 35.28503  83.22286  1.000 94.68337  ? 595 THR   B O   1 
ATOM   6249 C  CB  . THR   B 2 324 ? 48.01110 36.43923  85.10179  1.000 98.49911  ? 595 THR   B CB  1 
ATOM   6250 O  OG1 . THR   B 2 324 ? 48.59356 36.16663  83.82123  1.000 107.80759 ? 595 THR   B OG1 1 
ATOM   6251 C  CG2 . THR   B 2 324 ? 49.05694 36.22235  86.18676  1.000 89.48399  ? 595 THR   B CG2 1 
ATOM   6252 N  N   . ALA   B 2 325 ? 44.78527 36.71040  84.71877  1.000 81.81123  ? 596 ALA   B N   1 
ATOM   6253 C  CA  . ALA   B 2 325 ? 43.62793 37.00370  83.88754  1.000 74.53677  ? 596 ALA   B CA  1 
ATOM   6254 C  C   . ALA   B 2 325 ? 43.67647 38.44072  83.38794  1.000 78.15591  ? 596 ALA   B C   1 
ATOM   6255 O  O   . ALA   B 2 325 ? 44.35574 39.29579  83.95772  1.000 85.18301  ? 596 ALA   B O   1 
ATOM   6256 C  CB  . ALA   B 2 325 ? 42.32471 36.76072  84.65691  1.000 76.97267  ? 596 ALA   B CB  1 
ATOM   6257 N  N   . SER   B 2 326 ? 42.94179 38.70241  82.30911  1.000 75.98886  ? 597 SER   B N   1 
ATOM   6258 C  CA  . SER   B 2 326 ? 42.77328 40.07573  81.85809  1.000 70.01155  ? 597 SER   B CA  1 
ATOM   6259 C  C   . SER   B 2 326 ? 41.49818 40.17206  81.03610  1.000 69.24342  ? 597 SER   B C   1 
ATOM   6260 O  O   . SER   B 2 326 ? 41.22485 39.30908  80.20006  1.000 73.99970  ? 597 SER   B O   1 
ATOM   6261 C  CB  . SER   B 2 326 ? 43.97636 40.54972  81.04058  1.000 73.57052  ? 597 SER   B CB  1 
ATOM   6262 O  OG  . SER   B 2 326 ? 43.90604 41.94352  80.79512  1.000 81.12861  ? 597 SER   B OG  1 
ATOM   6263 N  N   . VAL   B 2 327 ? 40.71938 41.21939  81.29007  1.000 68.27773  ? 598 VAL   B N   1 
ATOM   6264 C  CA  . VAL   B 2 327 ? 39.42064 41.40121  80.65033  1.000 73.01589  ? 598 VAL   B CA  1 
ATOM   6265 C  C   . VAL   B 2 327 ? 39.26851 42.85227  80.21426  1.000 79.77612  ? 598 VAL   B C   1 
ATOM   6266 O  O   . VAL   B 2 327 ? 39.58032 43.77806  80.96958  1.000 78.49381  ? 598 VAL   B O   1 
ATOM   6267 C  CB  . VAL   B 2 327 ? 38.25744 40.99851  81.58334  1.000 73.35480  ? 598 VAL   B CB  1 
ATOM   6268 C  CG1 . VAL   B 2 327 ? 36.93374 41.12074  80.85183  1.000 75.24274  ? 598 VAL   B CG1 1 
ATOM   6269 C  CG2 . VAL   B 2 327 ? 38.44288 39.58189  82.11188  1.000 75.94737  ? 598 VAL   B CG2 1 
ATOM   6270 N  N   . LYS   B 2 328 ? 38.78279 43.04627  78.99313  1.000 80.97398  ? 599 LYS   B N   1 
ATOM   6271 C  CA  . LYS   B 2 328 ? 38.40745 44.35972  78.49641  1.000 78.77512  ? 599 LYS   B CA  1 
ATOM   6272 C  C   . LYS   B 2 328 ? 36.96389 44.65450  78.88308  1.000 80.85656  ? 599 LYS   B C   1 
ATOM   6273 O  O   . LYS   B 2 328 ? 36.14458 43.74449  79.03317  1.000 90.18742  ? 599 LYS   B O   1 
ATOM   6274 C  CB  . LYS   B 2 328 ? 38.57243 44.42515  76.97717  1.000 80.27479  ? 599 LYS   B CB  1 
ATOM   6275 C  CG  . LYS   B 2 328 ? 38.56788 45.82542  76.38912  1.000 81.12051  ? 599 LYS   B CG  1 
ATOM   6276 C  CD  . LYS   B 2 328 ? 38.81609 45.77561  74.88979  1.000 81.42529  ? 599 LYS   B CD  1 
ATOM   6277 C  CE  . LYS   B 2 328 ? 39.01526 47.16377  74.30796  1.000 89.59532  ? 599 LYS   B CE  1 
ATOM   6278 N  NZ  . LYS   B 2 328 ? 39.34582 47.10575  72.85687  1.000 94.02170  ? 599 LYS   B NZ  1 
ATOM   6279 N  N   . VAL   B 2 329 ? 36.65602 45.93718  79.04761  1.000 80.62314  ? 600 VAL   B N   1 
ATOM   6280 C  CA  . VAL   B 2 329 ? 35.33711 46.37573  79.48950  1.000 88.08621  ? 600 VAL   B CA  1 
ATOM   6281 C  C   . VAL   B 2 329 ? 34.74881 47.29551  78.42969  1.000 93.55216  ? 600 VAL   B C   1 
ATOM   6282 O  O   . VAL   B 2 329 ? 35.34407 48.32646  78.09111  1.000 94.65476  ? 600 VAL   B O   1 
ATOM   6283 C  CB  . VAL   B 2 329 ? 35.39607 47.07630  80.85531  1.000 82.30047  ? 600 VAL   B CB  1 
ATOM   6284 C  CG1 . VAL   B 2 329 ? 35.22844 46.06143  81.97300  1.000 76.23189  ? 600 VAL   B CG1 1 
ATOM   6285 C  CG2 . VAL   B 2 329 ? 36.71125 47.81635  81.00814  1.000 84.06097  ? 600 VAL   B CG2 1 
ATOM   6286 N  N   . THR   B 2 330 ? 33.58572 46.91754  77.90536  1.000 96.25909  ? 601 THR   B N   1 
ATOM   6287 C  CA  . THR   B 2 330 ? 32.82208 47.73254  76.97422  1.000 97.41990  ? 601 THR   B CA  1 
ATOM   6288 C  C   . THR   B 2 330 ? 31.36019 47.72515  77.39916  1.000 109.46870 ? 601 THR   B C   1 
ATOM   6289 O  O   . THR   B 2 330 ? 30.94877 46.96037  78.27667  1.000 112.38185 ? 601 THR   B O   1 
ATOM   6290 C  CB  . THR   B 2 330 ? 32.95230 47.22680  75.52951  1.000 93.91831  ? 601 THR   B CB  1 
ATOM   6291 O  OG1 . THR   B 2 330 ? 32.55501 45.85143  75.46462  1.000 93.68215  ? 601 THR   B OG1 1 
ATOM   6292 C  CG2 . THR   B 2 330 ? 34.38501 47.36430  75.03304  1.000 85.56250  ? 601 THR   B CG2 1 
ATOM   6293 N  N   . ASP   B 2 331 ? 30.57475 48.59540  76.76213  1.000 111.80351 ? 602 ASP   B N   1 
ATOM   6294 C  CA  . ASP   B 2 331 ? 29.13166 48.68231  76.99174  1.000 115.56048 ? 602 ASP   B CA  1 
ATOM   6295 C  C   . ASP   B 2 331 ? 28.80199 48.98998  78.45000  1.000 127.17711 ? 602 ASP   B C   1 
ATOM   6296 O  O   . ASP   B 2 331 ? 27.75152 48.58938  78.95688  1.000 132.70249 ? 602 ASP   B O   1 
ATOM   6297 C  CB  . ASP   B 2 331 ? 28.42012 47.40021  76.54764  1.000 111.46226 ? 602 ASP   B CB  1 
ATOM   6298 C  CG  . ASP   B 2 331 ? 28.90399 46.90185  75.20137  1.000 112.03103 ? 602 ASP   B CG  1 
ATOM   6299 O  OD1 . ASP   B 2 331 ? 29.33043 47.73512  74.37495  1.000 113.59111 ? 602 ASP   B OD1 1 
ATOM   6300 O  OD2 . ASP   B 2 331 ? 28.86132 45.67468  74.97148  1.000 106.73806 ? 602 ASP   B OD2 1 
ATOM   6301 N  N   . LEU   B 2 332 ? 29.69496 49.70007  79.13978  1.000 126.13402 ? 603 LEU   B N   1 
ATOM   6302 C  CA  . LEU   B 2 332 ? 29.46952 50.08530  80.53264  1.000 128.21057 ? 603 LEU   B CA  1 
ATOM   6303 C  C   . LEU   B 2 332 ? 28.42764 51.20120  80.55528  1.000 144.50783 ? 603 LEU   B C   1 
ATOM   6304 O  O   . LEU   B 2 332 ? 28.73356 52.39076  80.67030  1.000 137.37544 ? 603 LEU   B O   1 
ATOM   6305 C  CB  . LEU   B 2 332 ? 30.77787 50.50437  81.19226  1.000 124.42728 ? 603 LEU   B CB  1 
ATOM   6306 C  CG  . LEU   B 2 332 ? 31.82987 49.39424  81.27519  1.000 117.00757 ? 603 LEU   B CG  1 
ATOM   6307 C  CD1 . LEU   B 2 332 ? 33.15674 49.91790  81.80562  1.000 111.23056 ? 603 LEU   B CD1 1 
ATOM   6308 C  CD2 . LEU   B 2 332 ? 31.32527 48.24359  82.13423  1.000 113.48928 ? 603 LEU   B CD2 1 
ATOM   6309 N  N   . ASN   B 2 333 ? 27.16066 50.79201  80.44659  1.000 160.40498 ? 604 ASN   B N   1 
ATOM   6310 C  CA  . ASN   B 2 333 ? 26.05766 51.73461  80.29134  1.000 165.98814 ? 604 ASN   B CA  1 
ATOM   6311 C  C   . ASN   B 2 333 ? 25.70854 52.45128  81.59113  1.000 165.19912 ? 604 ASN   B C   1 
ATOM   6312 O  O   . ASN   B 2 333 ? 25.20747 53.58134  81.55046  1.000 158.84408 ? 604 ASN   B O   1 
ATOM   6313 C  CB  . ASN   B 2 333 ? 24.83076 50.99789  79.74125  1.000 160.20074 ? 604 ASN   B CB  1 
ATOM   6314 C  CG  . ASN   B 2 333 ? 23.52310 51.68555  80.08422  1.000 156.32981 ? 604 ASN   B CG  1 
ATOM   6315 O  OD1 . ASN   B 2 333 ? 23.12892 52.65794  79.44055  1.000 150.05519 ? 604 ASN   B OD1 1 
ATOM   6316 N  ND2 . ASN   B 2 333 ? 22.83663 51.17262  81.09907  1.000 157.67840 ? 604 ASN   B ND2 1 
ATOM   6317 N  N   . SER   B 2 334 ? 25.97473 51.83053  82.74302  1.000 164.43626 ? 605 SER   B N   1 
ATOM   6318 C  CA  . SER   B 2 334 ? 25.52323 52.39113  84.01418  1.000 152.53691 ? 605 SER   B CA  1 
ATOM   6319 C  C   . SER   B 2 334 ? 26.17185 53.74368  84.29450  1.000 146.30341 ? 605 SER   B C   1 
ATOM   6320 O  O   . SER   B 2 334 ? 25.47768 54.74883  84.48854  1.000 152.36264 ? 605 SER   B O   1 
ATOM   6321 C  CB  . SER   B 2 334 ? 25.80053 51.40561  85.15041  1.000 142.60523 ? 605 SER   B CB  1 
ATOM   6322 O  OG  . SER   B 2 334 ? 24.85621 50.34928  85.14953  1.000 143.86668 ? 605 SER   B OG  1 
ATOM   6323 N  N   . SER   B 2 335 ? 27.50535 53.79222  84.32213  1.000 135.51628 ? 739 SER   B N   1 
ATOM   6324 C  CA  . SER   B 2 335 ? 28.18470 55.03501  84.67441  1.000 132.57946 ? 739 SER   B CA  1 
ATOM   6325 C  C   . SER   B 2 335 ? 29.63865 55.07487  84.21508  1.000 130.51670 ? 739 SER   B C   1 
ATOM   6326 O  O   . SER   B 2 335 ? 30.08705 56.07681  83.64759  1.000 121.99391 ? 739 SER   B O   1 
ATOM   6327 C  CB  . SER   B 2 335 ? 28.12838 55.25911  86.18933  1.000 116.74893 ? 739 SER   B CB  1 
ATOM   6328 O  OG  . SER   B 2 335 ? 26.80662 55.52635  86.62683  1.000 105.79096 ? 739 SER   B OG  1 
ATOM   6329 N  N   . LEU   B 2 336 ? 30.38041 53.99488  84.45210  1.000 128.01181 ? 740 LEU   B N   1 
ATOM   6330 C  CA  . LEU   B 2 336 ? 31.84107 54.00700  84.35944  1.000 120.02539 ? 740 LEU   B CA  1 
ATOM   6331 C  C   . LEU   B 2 336 ? 32.29011 54.02950  82.90146  1.000 115.50208 ? 740 LEU   B C   1 
ATOM   6332 O  O   . LEU   B 2 336 ? 32.53597 52.99176  82.28373  1.000 121.96453 ? 740 LEU   B O   1 
ATOM   6333 C  CB  . LEU   B 2 336 ? 32.42045 52.80500  85.09316  1.000 114.45477 ? 740 LEU   B CB  1 
ATOM   6334 C  CG  . LEU   B 2 336 ? 32.15002 52.78492  86.59983  1.000 118.46761 ? 740 LEU   B CG  1 
ATOM   6335 C  CD1 . LEU   B 2 336 ? 32.69338 51.51414  87.22623  1.000 107.38037 ? 740 LEU   B CD1 1 
ATOM   6336 C  CD2 . LEU   B 2 336 ? 32.75754 54.01322  87.25760  1.000 109.52176 ? 740 LEU   B CD2 1 
ATOM   6337 N  N   . LYS   B 2 337 ? 32.41273 55.23472  82.34429  1.000 112.07687 ? 741 LYS   B N   1 
ATOM   6338 C  CA  . LYS   B 2 337 ? 33.11840 55.41181  81.08258  1.000 115.34250 ? 741 LYS   B CA  1 
ATOM   6339 C  C   . LYS   B 2 337 ? 34.61075 55.62893  81.29127  1.000 113.53609 ? 741 LYS   B C   1 
ATOM   6340 O  O   . LYS   B 2 337 ? 35.38604 55.49704  80.33686  1.000 117.43079 ? 741 LYS   B O   1 
ATOM   6341 C  CB  . LYS   B 2 337 ? 32.52458 56.58836  80.29590  1.000 120.72010 ? 741 LYS   B CB  1 
ATOM   6342 C  CG  . LYS   B 2 337 ? 32.89753 56.60366  78.81463  1.000 127.65309 ? 741 LYS   B CG  1 
ATOM   6343 C  CD  . LYS   B 2 337 ? 33.97998 57.63514  78.50449  1.000 133.17125 ? 741 LYS   B CD  1 
ATOM   6344 C  CE  . LYS   B 2 337 ? 34.96386 57.12590  77.45515  1.000 126.66464 ? 741 LYS   B CE  1 
ATOM   6345 N  NZ  . LYS   B 2 337 ? 35.90792 56.12391  78.02628  1.000 118.71723 ? 741 LYS   B NZ  1 
ATOM   6346 N  N   . GLU   B 2 338 ? 35.02509 55.95136  82.52028  1.000 108.58989 ? 742 GLU   B N   1 
ATOM   6347 C  CA  . GLU   B 2 338 ? 36.44638 56.08486  82.82077  1.000 106.31901 ? 742 GLU   B CA  1 
ATOM   6348 C  C   . GLU   B 2 338 ? 37.19982 54.80233  82.49406  1.000 105.85062 ? 742 GLU   B C   1 
ATOM   6349 O  O   . GLU   B 2 338 ? 38.33220 54.84691  81.99975  1.000 97.90233  ? 742 GLU   B O   1 
ATOM   6350 C  CB  . GLU   B 2 338 ? 36.63378 56.45717  84.29141  1.000 108.88784 ? 742 GLU   B CB  1 
ATOM   6351 C  CG  . GLU   B 2 338 ? 38.08347 56.46735  84.75222  1.000 110.88732 ? 742 GLU   B CG  1 
ATOM   6352 C  CD  . GLU   B 2 338 ? 38.21591 56.34491  86.25796  1.000 114.74996 ? 742 GLU   B CD  1 
ATOM   6353 O  OE1 . GLU   B 2 338 ? 37.18782 56.45646  86.95847  1.000 117.59995 ? 742 GLU   B OE1 1 
ATOM   6354 O  OE2 . GLU   B 2 338 ? 39.34745 56.12904  86.74074  1.000 109.72931 ? 742 GLU   B OE2 1 
ATOM   6355 N  N   . TYR   B 2 339 ? 36.58468 53.64980  82.75545  1.000 107.06438 ? 743 TYR   B N   1 
ATOM   6356 C  CA  . TYR   B 2 339 ? 37.19625 52.36188  82.46202  1.000 103.03411 ? 743 TYR   B CA  1 
ATOM   6357 C  C   . TYR   B 2 339 ? 36.90358 51.86930  81.05160  1.000 102.23322 ? 743 TYR   B C   1 
ATOM   6358 O  O   . TYR   B 2 339 ? 37.48540 50.86233  80.63441  1.000 100.14020 ? 743 TYR   B O   1 
ATOM   6359 C  CB  . TYR   B 2 339 ? 36.72472 51.30856  83.47168  1.000 99.30086  ? 743 TYR   B CB  1 
ATOM   6360 C  CG  . TYR   B 2 339 ? 36.97950 51.67784  84.91581  1.000 101.59495 ? 743 TYR   B CG  1 
ATOM   6361 C  CD1 . TYR   B 2 339 ? 38.23468 51.50826  85.48590  1.000 101.73207 ? 743 TYR   B CD1 1 
ATOM   6362 C  CD2 . TYR   B 2 339 ? 35.96265 52.18950  85.71114  1.000 102.59200 ? 743 TYR   B CD2 1 
ATOM   6363 C  CE1 . TYR   B 2 339 ? 38.47135 51.84333  86.80682  1.000 102.43791 ? 743 TYR   B CE1 1 
ATOM   6364 C  CE2 . TYR   B 2 339 ? 36.18941 52.52681  87.03276  1.000 102.65574 ? 743 TYR   B CE2 1 
ATOM   6365 C  CZ  . TYR   B 2 339 ? 37.44513 52.35157  87.57492  1.000 103.32915 ? 743 TYR   B CZ  1 
ATOM   6366 O  OH  . TYR   B 2 339 ? 37.67580 52.68569  88.88977  1.000 105.28144 ? 743 TYR   B OH  1 
ATOM   6367 N  N   . GLU   B 2 340 ? 36.02670 52.54884  80.31452  1.000 102.78973 ? 744 GLU   B N   1 
ATOM   6368 C  CA  . GLU   B 2 340 ? 35.65972 52.11113  78.97294  1.000 99.50197  ? 744 GLU   B CA  1 
ATOM   6369 C  C   . GLU   B 2 340 ? 36.88243 52.10704  78.06269  1.000 98.28096  ? 744 GLU   B C   1 
ATOM   6370 O  O   . GLU   B 2 340 ? 37.54482 53.13518  77.89055  1.000 97.83047  ? 744 GLU   B O   1 
ATOM   6371 C  CB  . GLU   B 2 340 ? 34.57202 53.02435  78.40667  1.000 102.10805 ? 744 GLU   B CB  1 
ATOM   6372 C  CG  . GLU   B 2 340 ? 33.91555 52.51820  77.12950  1.000 101.27339 ? 744 GLU   B CG  1 
ATOM   6373 C  CD  . GLU   B 2 340 ? 32.82318 51.49947  77.39426  1.000 102.16731 ? 744 GLU   B CD  1 
ATOM   6374 O  OE1 . GLU   B 2 340 ? 32.60279 51.15262  78.57336  1.000 101.31723 ? 744 GLU   B OE1 1 
ATOM   6375 O  OE2 . GLU   B 2 340 ? 32.18060 51.04906  76.42265  1.000 107.11177 ? 744 GLU   B OE2 1 
ATOM   6376 N  N   . GLY   B 2 341 ? 37.18173 50.94373  77.48454  1.000 98.61712  ? 745 GLY   B N   1 
ATOM   6377 C  CA  . GLY   B 2 341 ? 38.33406 50.76901  76.63353  1.000 94.24627  ? 745 GLY   B CA  1 
ATOM   6378 C  C   . GLY   B 2 341 ? 39.56841 50.24573  77.33698  1.000 88.86828  ? 745 GLY   B C   1 
ATOM   6379 O  O   . GLY   B 2 341 ? 40.43323 49.65140  76.68201  1.000 85.45367  ? 745 GLY   B O   1 
ATOM   6380 N  N   . LYS   B 2 342 ? 39.67691 50.44916  78.64782  1.000 88.38742  ? 746 LYS   B N   1 
ATOM   6381 C  CA  . LYS   B 2 342 ? 40.82849 49.96967  79.39166  1.000 83.83006  ? 746 LYS   B CA  1 
ATOM   6382 C  C   . LYS   B 2 342 ? 40.74174 48.45674  79.58762  1.000 81.97728  ? 746 LYS   B C   1 
ATOM   6383 O  O   . LYS   B 2 342 ? 39.73798 47.81177  79.26986  1.000 80.44776  ? 746 LYS   B O   1 
ATOM   6384 C  CB  . LYS   B 2 342 ? 40.92238 50.67586  80.74338  1.000 82.16237  ? 746 LYS   B CB  1 
ATOM   6385 C  CG  . LYS   B 2 342 ? 40.84220 52.19202  80.66086  1.000 89.43423  ? 746 LYS   B CG  1 
ATOM   6386 C  CD  . LYS   B 2 342 ? 42.01208 52.76802  79.88402  1.000 88.36905  ? 746 LYS   B CD  1 
ATOM   6387 C  CE  . LYS   B 2 342 ? 41.86892 54.27076  79.70729  1.000 82.02137  ? 746 LYS   B CE  1 
ATOM   6388 N  NZ  . LYS   B 2 342 ? 40.67841 54.62314  78.88567  1.000 72.74595  ? 746 LYS   B NZ  1 
ATOM   6389 N  N   . TRP   B 2 343 ? 41.81748 47.88976  80.12566  1.000 84.04826  ? 747 TRP   B N   1 
ATOM   6390 C  CA  . TRP   B 2 343 ? 41.90455 46.46200  80.39982  1.000 86.06295  ? 747 TRP   B CA  1 
ATOM   6391 C  C   . TRP   B 2 343 ? 42.18268 46.24292  81.88005  1.000 90.03949  ? 747 TRP   B C   1 
ATOM   6392 O  O   . TRP   B 2 343 ? 43.13773 46.80649  82.42743  1.000 94.02596  ? 747 TRP   B O   1 
ATOM   6393 C  CB  . TRP   B 2 343 ? 43.00218 45.80124  79.55743  1.000 89.10398  ? 747 TRP   B CB  1 
ATOM   6394 C  CG  . TRP   B 2 343 ? 42.61991 45.55059  78.12377  1.000 90.51184  ? 747 TRP   B CG  1 
ATOM   6395 C  CD1 . TRP   B 2 343 ? 42.61655 46.45801  77.10359  1.000 92.04618  ? 747 TRP   B CD1 1 
ATOM   6396 C  CD2 . TRP   B 2 343 ? 42.20237 44.30344  77.55124  1.000 93.54892  ? 747 TRP   B CD2 1 
ATOM   6397 N  NE1 . TRP   B 2 343 ? 42.21558 45.85560  75.93460  1.000 92.37034  ? 747 TRP   B NE1 1 
ATOM   6398 C  CE2 . TRP   B 2 343 ? 41.95638 44.53320  76.18237  1.000 89.00773  ? 747 TRP   B CE2 1 
ATOM   6399 C  CE3 . TRP   B 2 343 ? 42.00948 43.01661  78.06412  1.000 91.97123  ? 747 TRP   B CE3 1 
ATOM   6400 C  CZ2 . TRP   B 2 343 ? 41.52806 43.52418  75.32062  1.000 82.00843  ? 747 TRP   B CZ2 1 
ATOM   6401 C  CZ3 . TRP   B 2 343 ? 41.58331 42.01648  77.20670  1.000 85.91671  ? 747 TRP   B CZ3 1 
ATOM   6402 C  CH2 . TRP   B 2 343 ? 41.34690 42.27644  75.85109  1.000 83.98278  ? 747 TRP   B CH2 1 
ATOM   6403 N  N   . LEU   B 2 344 ? 41.35114 45.42851  82.52555  1.000 82.04590  ? 748 LEU   B N   1 
ATOM   6404 C  CA  . LEU   B 2 344 ? 41.60856 45.00302  83.89091  1.000 79.57859  ? 748 LEU   B CA  1 
ATOM   6405 C  C   . LEU   B 2 344 ? 42.50456 43.77365  83.88084  1.000 76.87945  ? 748 LEU   B C   1 
ATOM   6406 O  O   . LEU   B 2 344 ? 42.29217 42.84079  83.10180  1.000 77.34596  ? 748 LEU   B O   1 
ATOM   6407 C  CB  . LEU   B 2 344 ? 40.30665 44.68951  84.62840  1.000 76.29968  ? 748 LEU   B CB  1 
ATOM   6408 C  CG  . LEU   B 2 344 ? 39.37756 45.85612  84.97105  1.000 83.71991  ? 748 LEU   B CG  1 
ATOM   6409 C  CD1 . LEU   B 2 344 ? 38.39081 46.12011  83.84406  1.000 83.66086  ? 748 LEU   B CD1 1 
ATOM   6410 C  CD2 . LEU   B 2 344 ? 38.65195 45.58758  86.27923  1.000 82.62381  ? 748 LEU   B CD2 1 
ATOM   6411 N  N   . LEU   B 2 345 ? 43.51186 43.78609  84.74627  1.000 81.86272  ? 749 LEU   B N   1 
ATOM   6412 C  CA  . LEU   B 2 345 ? 44.45001 42.68504  84.89851  1.000 81.97149  ? 749 LEU   B CA  1 
ATOM   6413 C  C   . LEU   B 2 345 ? 44.31554 42.11017  86.30098  1.000 80.79347  ? 749 LEU   B C   1 
ATOM   6414 O  O   . LEU   B 2 345 ? 44.24131 42.85518  87.28102  1.000 82.34573  ? 749 LEU   B O   1 
ATOM   6415 C  CB  . LEU   B 2 345 ? 45.89024 43.15154  84.64090  1.000 79.71703  ? 749 LEU   B CB  1 
ATOM   6416 C  CG  . LEU   B 2 345 ? 47.01050 42.10837  84.59911  1.000 81.62993  ? 749 LEU   B CG  1 
ATOM   6417 C  CD1 . LEU   B 2 345 ? 48.06393 42.51991  83.58502  1.000 93.79732  ? 749 LEU   B CD1 1 
ATOM   6418 C  CD2 . LEU   B 2 345 ? 47.64667 41.92315  85.96995  1.000 81.01063  ? 749 LEU   B CD2 1 
ATOM   6419 N  N   . PHE   B 2 346 ? 44.28388 40.78407  86.39270  1.000 77.94204  ? 750 PHE   B N   1 
ATOM   6420 C  CA  . PHE   B 2 346 ? 44.09017 40.07290  87.65117  1.000 74.53704  ? 750 PHE   B CA  1 
ATOM   6421 C  C   . PHE   B 2 346 ? 45.30559 39.19073  87.89561  1.000 80.23651  ? 750 PHE   B C   1 
ATOM   6422 O  O   . PHE   B 2 346 ? 45.55743 38.24972  87.13071  1.000 85.13530  ? 750 PHE   B O   1 
ATOM   6423 C  CB  . PHE   B 2 346 ? 42.81364 39.23353  87.61898  1.000 73.09052  ? 750 PHE   B CB  1 
ATOM   6424 C  CG  . PHE   B 2 346 ? 41.55541 40.03924  87.47402  1.000 67.61146  ? 750 PHE   B CG  1 
ATOM   6425 C  CD1 . PHE   B 2 346 ? 41.13015 40.46918  86.22793  1.000 70.84897  ? 750 PHE   B CD1 1 
ATOM   6426 C  CD2 . PHE   B 2 346 ? 40.78854 40.35260  88.58324  1.000 71.98686  ? 750 PHE   B CD2 1 
ATOM   6427 C  CE1 . PHE   B 2 346 ? 39.97004 41.20629  86.09256  1.000 75.82939  ? 750 PHE   B CE1 1 
ATOM   6428 C  CE2 . PHE   B 2 346 ? 39.62636 41.08746  88.45453  1.000 75.35991  ? 750 PHE   B CE2 1 
ATOM   6429 C  CZ  . PHE   B 2 346 ? 39.21690 41.51565  87.20735  1.000 75.76528  ? 750 PHE   B CZ  1 
ATOM   6430 N  N   . ASP   B 2 347 ? 46.05354 39.49990  88.95580  1.000 79.22834  ? 751 ASP   B N   1 
ATOM   6431 C  CA  . ASP   B 2 347 ? 47.17156 38.68340  89.41601  1.000 88.12435  ? 751 ASP   B CA  1 
ATOM   6432 C  C   . ASP   B 2 347 ? 46.97224 38.44733  90.90642  1.000 89.24068  ? 751 ASP   B C   1 
ATOM   6433 O  O   . ASP   B 2 347 ? 47.07182 39.38713  91.70393  1.000 89.50067  ? 751 ASP   B O   1 
ATOM   6434 C  CB  . ASP   B 2 347 ? 48.51273 39.36370  89.13719  1.000 87.27587  ? 751 ASP   B CB  1 
ATOM   6435 C  CG  . ASP   B 2 347 ? 49.69072 38.57048  89.66991  1.000 97.91241  ? 751 ASP   B CG  1 
ATOM   6436 O  OD1 . ASP   B 2 347 ? 49.90577 37.43345  89.19930  1.000 99.94903  ? 751 ASP   B OD1 1 
ATOM   6437 O  OD2 . ASP   B 2 347 ? 50.40394 39.08464  90.55707  1.000 101.82496 ? 751 ASP   B OD2 1 
ATOM   6438 N  N   . ASP   B 2 348 ? 46.67773 37.20185  91.27380  1.000 88.57971  ? 752 ASP   B N   1 
ATOM   6439 C  CA  . ASP   B 2 348 ? 46.35640 36.82005  92.65564  1.000 91.71868  ? 752 ASP   B CA  1 
ATOM   6440 C  C   . ASP   B 2 348 ? 45.18790 37.69613  93.10380  1.000 89.23922  ? 752 ASP   B C   1 
ATOM   6441 O  O   . ASP   B 2 348 ? 44.20216 37.81837  92.35831  1.000 84.02455  ? 752 ASP   B O   1 
ATOM   6442 C  CB  . ASP   B 2 348 ? 47.61221 36.89922  93.51500  1.000 93.99971  ? 752 ASP   B CB  1 
ATOM   6443 C  CG  . ASP   B 2 348 ? 48.57920 35.76661  93.23624  1.000 97.73349  ? 752 ASP   B CG  1 
ATOM   6444 O  OD1 . ASP   B 2 348 ? 48.12397 34.60673  93.13589  1.000 99.55091  ? 752 ASP   B OD1 1 
ATOM   6445 O  OD2 . ASP   B 2 348 ? 49.79252 36.03422  93.11207  1.000 95.30222  ? 752 ASP   B OD2 1 
ATOM   6446 N  N   . SER   B 2 349 ? 45.24584 38.32042  94.27712  1.000 88.34418  ? 753 SER   B N   1 
ATOM   6447 C  CA  . SER   B 2 349 ? 44.16776 39.17252  94.75802  1.000 86.30286  ? 753 SER   B CA  1 
ATOM   6448 C  C   . SER   B 2 349 ? 44.27606 40.60714  94.26097  1.000 81.25050  ? 753 SER   B C   1 
ATOM   6449 O  O   . SER   B 2 349 ? 43.46343 41.44716  94.66152  1.000 73.43248  ? 753 SER   B O   1 
ATOM   6450 C  CB  . SER   B 2 349 ? 44.13462 39.16581  96.28979  1.000 82.12177  ? 753 SER   B CB  1 
ATOM   6451 O  OG  . SER   B 2 349 ? 45.32692 39.71263  96.82700  1.000 89.54246  ? 753 SER   B OG  1 
ATOM   6452 N  N   . GLU   B 2 350 ? 45.24714 40.91073  93.40395  1.000 85.24136  ? 754 GLU   B N   1 
ATOM   6453 C  CA  . GLU   B 2 350 ? 45.49118 42.27664  92.96101  1.000 83.41721  ? 754 GLU   B CA  1 
ATOM   6454 C  C   . GLU   B 2 350 ? 44.91926 42.47276  91.56203  1.000 80.73349  ? 754 GLU   B C   1 
ATOM   6455 O  O   . GLU   B 2 350 ? 45.34011 41.80321  90.61027  1.000 85.48630  ? 754 GLU   B O   1 
ATOM   6456 C  CB  . GLU   B 2 350 ? 46.98511 42.60017  92.98459  1.000 95.71065  ? 754 GLU   B CB  1 
ATOM   6457 C  CG  . GLU   B 2 350 ? 47.29472 44.08281  92.84452  1.000 94.82466  ? 754 GLU   B CG  1 
ATOM   6458 C  CD  . GLU   B 2 350 ? 48.75191 44.40531  93.11082  1.000 105.39222 ? 754 GLU   B CD  1 
ATOM   6459 O  OE1 . GLU   B 2 350 ? 49.57487 43.46622  93.14952  1.000 111.86541 ? 754 GLU   B OE1 1 
ATOM   6460 O  OE2 . GLU   B 2 350 ? 49.07307 45.59999  93.28463  1.000 107.25695 ? 754 GLU   B OE2 1 
ATOM   6461 N  N   . VAL   B 2 351 ? 43.96135 43.38795  91.44355  1.000 78.34172  ? 755 VAL   B N   1 
ATOM   6462 C  CA  . VAL   B 2 351 ? 43.41770 43.80852  90.15922  1.000 81.46227  ? 755 VAL   B CA  1 
ATOM   6463 C  C   . VAL   B 2 351 ? 43.96164 45.19604  89.84924  1.000 84.06515  ? 755 VAL   B C   1 
ATOM   6464 O  O   . VAL   B 2 351 ? 44.08982 46.04079  90.74321  1.000 87.46154  ? 755 VAL   B O   1 
ATOM   6465 C  CB  . VAL   B 2 351 ? 41.87471 43.79295  90.15336  1.000 80.87305  ? 755 VAL   B CB  1 
ATOM   6466 C  CG1 . VAL   B 2 351 ? 41.31691 44.71073  91.22797  1.000 82.69418  ? 755 VAL   B CG1 1 
ATOM   6467 C  CG2 . VAL   B 2 351 ? 41.33838 44.17937  88.78081  1.000 78.59450  ? 755 VAL   B CG2 1 
ATOM   6468 N  N   . LYS   B 2 352 ? 44.31227 45.41532  88.58591  1.000 89.94334  ? 756 LYS   B N   1 
ATOM   6469 C  CA  . LYS   B 2 352 ? 44.89952 46.66551  88.13147  1.000 97.90138  ? 756 LYS   B CA  1 
ATOM   6470 C  C   . LYS   B 2 352 ? 44.21148 47.11044  86.84945  1.000 94.27857  ? 756 LYS   B C   1 
ATOM   6471 O  O   . LYS   B 2 352 ? 43.61591 46.30704  86.12950  1.000 95.39037  ? 756 LYS   B O   1 
ATOM   6472 C  CB  . LYS   B 2 352 ? 46.40961 46.52470  87.88619  1.000 91.88578  ? 756 LYS   B CB  1 
ATOM   6473 C  CG  . LYS   B 2 352 ? 47.17968 45.90002  89.03783  1.000 89.55309  ? 756 LYS   B CG  1 
ATOM   6474 C  CD  . LYS   B 2 352 ? 48.59416 45.53675  88.61815  1.000 91.04464  ? 756 LYS   B CD  1 
ATOM   6475 C  CE  . LYS   B 2 352 ? 49.31182 44.76525  89.71252  1.000 98.41217  ? 756 LYS   B CE  1 
ATOM   6476 N  NZ  . LYS   B 2 352 ? 50.66747 44.32268  89.28547  1.000 100.82548 ? 756 LYS   B NZ  1 
ATOM   6477 N  N   . VAL   B 2 353 ? 44.30386 48.40642  86.56804  1.000 94.13414  ? 757 VAL   B N   1 
ATOM   6478 C  CA  . VAL   B 2 353 ? 43.79928 48.98895  85.33047  1.000 99.22569  ? 757 VAL   B CA  1 
ATOM   6479 C  C   . VAL   B 2 353 ? 44.99492 49.36419  84.46862  1.000 103.84376 ? 757 VAL   B C   1 
ATOM   6480 O  O   . VAL   B 2 353 ? 45.90739 50.05847  84.93355  1.000 110.24087 ? 757 VAL   B O   1 
ATOM   6481 C  CB  . VAL   B 2 353 ? 42.90815 50.21363  85.60136  1.000 104.09272 ? 757 VAL   B CB  1 
ATOM   6482 C  CG1 . VAL   B 2 353 ? 42.41927 50.81597  84.29110  1.000 93.95933  ? 757 VAL   B CG1 1 
ATOM   6483 C  CG2 . VAL   B 2 353 ? 41.73501 49.83066  86.48998  1.000 96.49943  ? 757 VAL   B CG2 1 
ATOM   6484 N  N   . THR   B 2 354 ? 44.99631 48.90413  83.21864  1.000 101.50588 ? 758 THR   B N   1 
ATOM   6485 C  CA  . THR   B 2 354 ? 46.08546 49.19195  82.30015  1.000 99.71863  ? 758 THR   B CA  1 
ATOM   6486 C  C   . THR   B 2 354 ? 45.51250 49.54125  80.93529  1.000 94.55160  ? 758 THR   B C   1 
ATOM   6487 O  O   . THR   B 2 354 ? 44.46233 49.03059  80.53486  1.000 92.11825  ? 758 THR   B O   1 
ATOM   6488 C  CB  . THR   B 2 354 ? 47.05790 48.00639  82.18260  1.000 96.17194  ? 758 THR   B CB  1 
ATOM   6489 O  OG1 . THR   B 2 354 ? 48.03617 48.28306  81.17349  1.000 93.32677  ? 758 THR   B OG1 1 
ATOM   6490 C  CG2 . THR   B 2 354 ? 46.31309 46.72766  81.82644  1.000 91.93210  ? 758 THR   B CG2 1 
ATOM   6491 N  N   . GLU   B 2 355 ? 46.21083 50.42768  80.22953  1.000 96.24845  ? 759 GLU   B N   1 
ATOM   6492 C  CA  . GLU   B 2 355 ? 45.79569 50.81980  78.89347  1.000 92.58012  ? 759 GLU   B CA  1 
ATOM   6493 C  C   . GLU   B 2 355 ? 45.89542 49.63469  77.93501  1.000 88.68463  ? 759 GLU   B C   1 
ATOM   6494 O  O   . GLU   B 2 355 ? 46.50297 48.60161  78.23221  1.000 93.75377  ? 759 GLU   B O   1 
ATOM   6495 C  CB  . GLU   B 2 355 ? 46.64307 51.98701  78.38654  1.000 91.96647  ? 759 GLU   B CB  1 
ATOM   6496 C  CG  . GLU   B 2 355 ? 46.25037 53.34637  78.95003  1.000 93.98272  ? 759 GLU   B CG  1 
ATOM   6497 C  CD  . GLU   B 2 355 ? 45.05009 53.95555  78.24375  1.000 100.07330 ? 759 GLU   B CD  1 
ATOM   6498 O  OE1 . GLU   B 2 355 ? 44.40309 53.25353  77.43784  1.000 101.00900 ? 759 GLU   B OE1 1 
ATOM   6499 O  OE2 . GLU   B 2 355 ? 44.75700 55.14449  78.49103  1.000 99.89726  ? 759 GLU   B OE2 1 
ATOM   6500 N  N   . GLU   B 2 356 ? 45.28374 49.79905  76.76092  1.000 77.85102  ? 760 GLU   B N   1 
ATOM   6501 C  CA  . GLU   B 2 356 ? 45.24991 48.70942  75.79200  1.000 86.92688  ? 760 GLU   B CA  1 
ATOM   6502 C  C   . GLU   B 2 356 ? 46.63685 48.42015  75.22996  1.000 93.84259  ? 760 GLU   B C   1 
ATOM   6503 O  O   . GLU   B 2 356 ? 47.00893 47.25341  75.05491  1.000 92.96262  ? 760 GLU   B O   1 
ATOM   6504 C  CB  . GLU   B 2 356 ? 44.26770 49.03910  74.66848  1.000 84.38325  ? 760 GLU   B CB  1 
ATOM   6505 C  CG  . GLU   B 2 356 ? 44.05411 47.90485  73.68070  1.000 86.12157  ? 760 GLU   B CG  1 
ATOM   6506 C  CD  . GLU   B 2 356 ? 42.94328 48.19571  72.69214  1.000 85.11038  ? 760 GLU   B CD  1 
ATOM   6507 O  OE1 . GLU   B 2 356 ? 42.28707 49.25027  72.82524  1.000 90.30992  ? 760 GLU   B OE1 1 
ATOM   6508 O  OE2 . GLU   B 2 356 ? 42.72567 47.36838  71.78243  1.000 81.87767  ? 760 GLU   B OE2 1 
ATOM   6509 N  N   . LYS   B 2 357 ? 47.42103 49.46492  74.95026  1.000 93.43157  ? 761 LYS   B N   1 
ATOM   6510 C  CA  . LYS   B 2 357 ? 48.73931 49.24891  74.36162  1.000 95.71825  ? 761 LYS   B CA  1 
ATOM   6511 C  C   . LYS   B 2 357 ? 49.68805 48.58317  75.35184  1.000 96.80949  ? 761 LYS   B C   1 
ATOM   6512 O  O   . LYS   B 2 357 ? 50.51240 47.74914  74.96098  1.000 102.01798 ? 761 LYS   B O   1 
ATOM   6513 C  CB  . LYS   B 2 357 ? 49.32293 50.56977  73.85470  1.000 97.03669  ? 761 LYS   B CB  1 
ATOM   6514 C  CG  . LYS   B 2 357 ? 49.61350 51.60564  74.92997  1.000 95.78374  ? 761 LYS   B CG  1 
ATOM   6515 C  CD  . LYS   B 2 357 ? 50.71772 52.55100  74.48076  1.000 92.58763  ? 761 LYS   B CD  1 
ATOM   6516 C  CE  . LYS   B 2 357 ? 50.99755 53.62271  75.52086  1.000 82.57946  ? 761 LYS   B CE  1 
ATOM   6517 N  NZ  . LYS   B 2 357 ? 49.86730 54.58295  75.64396  1.000 77.44198  ? 761 LYS   B NZ  1 
ATOM   6518 N  N   . ASP   B 2 358 ? 49.57777 48.92260  76.63905  1.000 93.52690  ? 762 ASP   B N   1 
ATOM   6519 C  CA  . ASP   B 2 358 ? 50.43044 48.28983  77.64046  1.000 92.93584  ? 762 ASP   B CA  1 
ATOM   6520 C  C   . ASP   B 2 358 ? 50.13524 46.79945  77.74775  1.000 95.87495  ? 762 ASP   B C   1 
ATOM   6521 O  O   . ASP   B 2 358 ? 51.05574 45.97984  77.83623  1.000 99.59897  ? 762 ASP   B O   1 
ATOM   6522 C  CB  . ASP   B 2 358 ? 50.24874 48.97382  78.99508  1.000 95.14752  ? 762 ASP   B CB  1 
ATOM   6523 C  CG  . ASP   B 2 358 ? 50.61532 50.44416  78.96022  1.000 103.48877 ? 762 ASP   B CG  1 
ATOM   6524 O  OD1 . ASP   B 2 358 ? 51.00889 50.93530  77.88122  1.000 105.57102 ? 762 ASP   B OD1 1 
ATOM   6525 O  OD2 . ASP   B 2 358 ? 50.51009 51.10874  80.01281  1.000 102.78582 ? 762 ASP   B OD2 1 
ATOM   6526 N  N   . PHE   B 2 359 ? 48.85463 46.42769  77.72118  1.000 97.41236  ? 763 PHE   B N   1 
ATOM   6527 C  CA  . PHE   B 2 359 ? 48.48962 45.01534  77.76195  1.000 100.08980 ? 763 PHE   B CA  1 
ATOM   6528 C  C   . PHE   B 2 359 ? 48.92953 44.29304  76.49253  1.000 99.34286  ? 763 PHE   B C   1 
ATOM   6529 O  O   . PHE   B 2 359 ? 49.44676 43.16831  76.55424  1.000 102.86770 ? 763 PHE   B O   1 
ATOM   6530 C  CB  . PHE   B 2 359 ? 46.98151 44.88492  77.97320  1.000 95.59594  ? 763 PHE   B CB  1 
ATOM   6531 C  CG  . PHE   B 2 359 ? 46.48066 43.47358  77.93818  1.000 94.47425  ? 763 PHE   B CG  1 
ATOM   6532 C  CD1 . PHE   B 2 359 ? 46.87983 42.55966  78.89706  1.000 97.14548  ? 763 PHE   B CD1 1 
ATOM   6533 C  CD2 . PHE   B 2 359 ? 45.59335 43.06564  76.95629  1.000 92.92404  ? 763 PHE   B CD2 1 
ATOM   6534 C  CE1 . PHE   B 2 359 ? 46.41659 41.26158  78.86818  1.000 101.62586 ? 763 PHE   B CE1 1 
ATOM   6535 C  CE2 . PHE   B 2 359 ? 45.12280 41.76810  76.92358  1.000 92.99216  ? 763 PHE   B CE2 1 
ATOM   6536 C  CZ  . PHE   B 2 359 ? 45.53169 40.86520  77.88260  1.000 97.33377  ? 763 PHE   B CZ  1 
ATOM   6537 N  N   . LEU   B 2 360 ? 48.74123 44.92872  75.33262  1.000 91.02473  ? 764 LEU   B N   1 
ATOM   6538 C  CA  . LEU   B 2 360 ? 49.16434 44.31980  74.07604  1.000 95.53707  ? 764 LEU   B CA  1 
ATOM   6539 C  C   . LEU   B 2 360 ? 50.67429 44.11956  74.03082  1.000 103.39815 ? 764 LEU   B C   1 
ATOM   6540 O  O   . LEU   B 2 360 ? 51.15254 43.14081  73.44558  1.000 106.69601 ? 764 LEU   B O   1 
ATOM   6541 C  CB  . LEU   B 2 360 ? 48.69964 45.17681  72.89703  1.000 97.09429  ? 764 LEU   B CB  1 
ATOM   6542 C  CG  . LEU   B 2 360 ? 47.34793 44.83985  72.25576  1.000 93.70525  ? 764 LEU   B CG  1 
ATOM   6543 C  CD1 . LEU   B 2 360 ? 46.24100 44.69871  73.29221  1.000 89.11129  ? 764 LEU   B CD1 1 
ATOM   6544 C  CD2 . LEU   B 2 360 ? 46.97595 45.89220  71.22098  1.000 85.75469  ? 764 LEU   B CD2 1 
ATOM   6545 N  N   . ASN   B 2 361 ? 51.43886 45.02976  74.64095  1.000 103.66254 ? 765 ASN   B N   1 
ATOM   6546 C  CA  . ASN   B 2 361 ? 52.88290 44.85163  74.73763  1.000 108.13161 ? 765 ASN   B CA  1 
ATOM   6547 C  C   . ASN   B 2 361 ? 53.25493 43.80616  75.78022  1.000 108.69189 ? 765 ASN   B C   1 
ATOM   6548 O  O   . ASN   B 2 361 ? 54.28686 43.14038  75.64338  1.000 109.94982 ? 765 ASN   B O   1 
ATOM   6549 C  CB  . ASN   B 2 361 ? 53.55780 46.18314  75.06822  1.000 107.95426 ? 765 ASN   B CB  1 
ATOM   6550 C  CG  . ASN   B 2 361 ? 53.47230 47.17884  73.92923  1.000 113.93800 ? 765 ASN   B CG  1 
ATOM   6551 O  OD1 . ASN   B 2 361 ? 52.72925 46.97880  72.96815  1.000 114.71485 ? 765 ASN   B OD1 1 
ATOM   6552 N  ND2 . ASN   B 2 361 ? 54.23421 48.26181  74.03231  1.000 114.79252 ? 765 ASN   B ND2 1 
ATOM   6553 N  N   . SER   B 2 362 ? 52.44354 43.66146  76.83119  1.000 106.40965 ? 766 SER   B N   1 
ATOM   6554 C  CA  . SER   B 2 362 ? 52.66172 42.58230  77.78694  1.000 108.40766 ? 766 SER   B CA  1 
ATOM   6555 C  C   . SER   B 2 362 ? 52.44555 41.22195  77.14017  1.000 114.78302 ? 766 SER   B C   1 
ATOM   6556 O  O   . SER   B 2 362 ? 53.07265 40.23681  77.54540  1.000 112.02359 ? 766 SER   B O   1 
ATOM   6557 C  CB  . SER   B 2 362 ? 51.73838 42.74970  78.99361  1.000 104.96105 ? 766 SER   B CB  1 
ATOM   6558 O  OG  . SER   B 2 362 ? 51.95210 43.99537  79.63449  1.000 109.51189 ? 766 SER   B OG  1 
ATOM   6559 N  N   . LEU   B 2 363 ? 51.56366 41.14747  76.14129  1.000 118.28627 ? 767 LEU   B N   1 
ATOM   6560 C  CA  . LEU   B 2 363 ? 51.38126 39.89868  75.40585  1.000 125.10634 ? 767 LEU   B CA  1 
ATOM   6561 C  C   . LEU   B 2 363 ? 52.59596 39.58926  74.53842  1.000 134.52957 ? 767 LEU   B C   1 
ATOM   6562 O  O   . LEU   B 2 363 ? 53.21617 38.52751  74.66811  1.000 139.61788 ? 767 LEU   B O   1 
ATOM   6563 C  CB  . LEU   B 2 363 ? 50.11694 39.96957  74.54692  1.000 125.66164 ? 767 LEU   B CB  1 
ATOM   6564 C  CG  . LEU   B 2 363 ? 48.85820 39.33043  75.12951  1.000 122.86850 ? 767 LEU   B CG  1 
ATOM   6565 C  CD1 . LEU   B 2 363 ? 48.50604 39.99697  76.43750  1.000 117.31875 ? 767 LEU   B CD1 1 
ATOM   6566 C  CD2 . LEU   B 2 363 ? 47.69947 39.41707  74.14751  1.000 108.11186 ? 767 LEU   B CD2 1 
ATOM   6567 N  N   . SER   B 2 364 ? 52.94781 40.50889  73.64655  1.000 134.13407 ? 768 SER   B N   1 
ATOM   6568 C  CA  . SER   B 2 364 ? 54.00339 40.29054  72.67294  1.000 134.78086 ? 768 SER   B CA  1 
ATOM   6569 C  C   . SER   B 2 364 ? 55.38175 40.42071  73.31648  1.000 135.74020 ? 768 SER   B C   1 
ATOM   6570 O  O   . SER   B 2 364 ? 55.53041 41.03912  74.37312  1.000 127.96520 ? 768 SER   B O   1 
ATOM   6571 C  CB  . SER   B 2 364 ? 53.85934 41.28777  71.52683  1.000 126.32297 ? 768 SER   B CB  1 
ATOM   6572 O  OG  . SER   B 2 364 ? 52.59777 41.15502  70.89497  1.000 123.87356 ? 768 SER   B OG  1 
ATOM   6573 N  N   . PRO   B 2 365 ? 56.41852 39.82810  72.69854  1.000 136.10851 ? 769 PRO   B N   1 
ATOM   6574 C  CA  . PRO   B 2 365 ? 57.79146 39.98275  73.19338  1.000 125.54276 ? 769 PRO   B CA  1 
ATOM   6575 C  C   . PRO   B 2 365 ? 58.28101 41.42682  73.12991  1.000 124.19242 ? 769 PRO   B C   1 
ATOM   6576 O  O   . PRO   B 2 365 ? 58.56552 42.00624  74.17811  1.000 119.61118 ? 769 PRO   B O   1 
ATOM   6577 C  CB  . PRO   B 2 365 ? 58.60908 39.09064  72.25010  1.000 119.47228 ? 769 PRO   B CB  1 
ATOM   6578 C  CG  . PRO   B 2 365 ? 57.75872 38.92824  71.03570  1.000 124.69238 ? 769 PRO   B CG  1 
ATOM   6579 C  CD  . PRO   B 2 365 ? 56.35520 38.91222  71.54673  1.000 129.67426 ? 769 PRO   B CD  1 
ATOM   6580 N  N   . PRO   B 2 369 ? 58.41318 37.35909  75.98472  1.000 125.29763 ? 773 PRO   B N   1 
ATOM   6581 C  CA  . PRO   B 2 369 ? 58.00329 35.95645  76.11036  1.000 128.85455 ? 773 PRO   B CA  1 
ATOM   6582 C  C   . PRO   B 2 369 ? 57.88828 35.52340  77.56754  1.000 127.56439 ? 773 PRO   B C   1 
ATOM   6583 O  O   . PRO   B 2 369 ? 58.23954 34.39319  77.90612  1.000 123.71388 ? 773 PRO   B O   1 
ATOM   6584 C  CB  . PRO   B 2 369 ? 59.12902 35.19413  75.40091  1.000 125.74866 ? 773 PRO   B CB  1 
ATOM   6585 C  CG  . PRO   B 2 369 ? 59.77251 36.20313  74.50575  1.000 130.97206 ? 773 PRO   B CG  1 
ATOM   6586 C  CD  . PRO   B 2 369 ? 59.68027 37.49699  75.24917  1.000 122.40707 ? 773 PRO   B CD  1 
ATOM   6587 N  N   . THR   B 2 370 ? 57.40025 36.42468  78.41903  1.000 128.36059 ? 774 THR   B N   1 
ATOM   6588 C  CA  . THR   B 2 370 ? 57.26800 36.14064  79.84256  1.000 128.97906 ? 774 THR   B CA  1 
ATOM   6589 C  C   . THR   B 2 370 ? 56.08814 35.21239  80.10165  1.000 123.42147 ? 774 THR   B C   1 
ATOM   6590 O  O   . THR   B 2 370 ? 56.27149 34.01137  80.32634  1.000 114.60692 ? 774 THR   B O   1 
ATOM   6591 C  CB  . THR   B 2 370 ? 57.10419 37.43921  80.63645  1.000 123.34511 ? 774 THR   B CB  1 
ATOM   6592 O  OG1 . THR   B 2 370 ? 58.17575 38.33544  80.31647  1.000 127.19283 ? 774 THR   B OG1 1 
ATOM   6593 C  CG2 . THR   B 2 370 ? 57.12020 37.15571  82.13140  1.000 113.88222 ? 774 THR   B CG2 1 
ATOM   6594 N  N   . SER   B 2 371 ? 54.87652 35.76027  80.07246  1.000 120.41444 ? 775 SER   B N   1 
ATOM   6595 C  CA  . SER   B 2 371 ? 53.65295 34.99937  80.28962  1.000 114.77442 ? 775 SER   B CA  1 
ATOM   6596 C  C   . SER   B 2 371 ? 52.92631 34.85490  78.95980  1.000 109.28585 ? 775 SER   B C   1 
ATOM   6597 O  O   . SER   B 2 371 ? 52.52312 35.85578  78.35789  1.000 108.55570 ? 775 SER   B O   1 
ATOM   6598 C  CB  . SER   B 2 371 ? 52.75795 35.68325  81.32367  1.000 109.92738 ? 775 SER   B CB  1 
ATOM   6599 O  OG  . SER   B 2 371 ? 53.42992 35.82867  82.56333  1.000 110.98511 ? 775 SER   B OG  1 
ATOM   6600 N  N   . THR   B 2 372 ? 52.76552 33.60749  78.50158  1.000 105.20767 ? 776 THR   B N   1 
ATOM   6601 C  CA  . THR   B 2 372 ? 52.08147 33.33198  77.24805  1.000 101.86352 ? 776 THR   B CA  1 
ATOM   6602 C  C   . THR   B 2 372 ? 50.59408 33.08931  77.48985  1.000 97.24217  ? 776 THR   B C   1 
ATOM   6603 O  O   . THR   B 2 372 ? 50.21020 32.51699  78.51517  1.000 96.39339  ? 776 THR   B O   1 
ATOM   6604 C  CB  . THR   B 2 372 ? 52.69446 32.11299  76.56275  1.000 97.42224  ? 776 THR   B CB  1 
ATOM   6605 O  OG1 . THR   B 2 372 ? 52.67249 30.99544  77.45968  1.000 94.16192  ? 776 THR   B OG1 1 
ATOM   6606 C  CG2 . THR   B 2 372 ? 54.13180 32.40094  76.15381  1.000 109.24443 ? 776 THR   B CG2 1 
ATOM   6607 N  N   . PRO   B 2 373 ? 49.73623 33.51605  76.56441  1.000 95.29455  ? 777 PRO   B N   1 
ATOM   6608 C  CA  . PRO   B 2 373 ? 48.29410 33.34586  76.76730  1.000 90.13380  ? 777 PRO   B CA  1 
ATOM   6609 C  C   . PRO   B 2 373 ? 47.87540 31.89073  76.63755  1.000 81.14458  ? 777 PRO   B C   1 
ATOM   6610 O  O   . PRO   B 2 373 ? 48.44440 31.11931  75.86140  1.000 82.58770  ? 777 PRO   B O   1 
ATOM   6611 C  CB  . PRO   B 2 373 ? 47.67767 34.20211  75.65611  1.000 90.98737  ? 777 PRO   B CB  1 
ATOM   6612 C  CG  . PRO   B 2 373 ? 48.70923 34.19887  74.58034  1.000 89.94838  ? 777 PRO   B CG  1 
ATOM   6613 C  CD  . PRO   B 2 373 ? 50.03996 34.18352  75.28594  1.000 97.50317  ? 777 PRO   B CD  1 
ATOM   6614 N  N   . TYR   B 2 374 ? 46.86069 31.52124  77.41500  1.000 77.79798  ? 778 TYR   B N   1 
ATOM   6615 C  CA  . TYR   B 2 374 ? 46.33271 30.16227  77.42217  1.000 77.83116  ? 778 TYR   B CA  1 
ATOM   6616 C  C   . TYR   B 2 374 ? 44.90754 30.06247  76.90474  1.000 76.72704  ? 778 TYR   B C   1 
ATOM   6617 O  O   . TYR   B 2 374 ? 44.56480 29.07486  76.25118  1.000 80.69713  ? 778 TYR   B O   1 
ATOM   6618 C  CB  . TYR   B 2 374 ? 46.39728 29.57591  78.83784  1.000 84.55736  ? 778 TYR   B CB  1 
ATOM   6619 C  CG  . TYR   B 2 374 ? 45.85151 28.16936  78.93900  1.000 81.80047  ? 778 TYR   B CG  1 
ATOM   6620 C  CD1 . TYR   B 2 374 ? 46.43007 27.12804  78.22594  1.000 85.79256  ? 778 TYR   B CD1 1 
ATOM   6621 C  CD2 . TYR   B 2 374 ? 44.76352 27.88109  79.75239  1.000 80.94128  ? 778 TYR   B CD2 1 
ATOM   6622 C  CE1 . TYR   B 2 374 ? 45.93670 25.84072  78.31369  1.000 89.27012  ? 778 TYR   B CE1 1 
ATOM   6623 C  CE2 . TYR   B 2 374 ? 44.26274 26.59570  79.84722  1.000 84.66753  ? 778 TYR   B CE2 1 
ATOM   6624 C  CZ  . TYR   B 2 374 ? 44.85397 25.57971  79.12568  1.000 89.81249  ? 778 TYR   B CZ  1 
ATOM   6625 O  OH  . TYR   B 2 374 ? 44.36293 24.29759  79.21459  1.000 92.26323  ? 778 TYR   B OH  1 
ATOM   6626 N  N   . LEU   B 2 375 ? 44.06423 31.05714  77.17493  1.000 75.52560  ? 779 LEU   B N   1 
ATOM   6627 C  CA  . LEU   B 2 375 ? 42.68097 31.03623  76.72011  1.000 72.75451  ? 779 LEU   B CA  1 
ATOM   6628 C  C   . LEU   B 2 375 ? 42.30650 32.39683  76.15542  1.000 69.34985  ? 779 LEU   B C   1 
ATOM   6629 O  O   . LEU   B 2 375 ? 42.68261 33.43079  76.71331  1.000 72.53386  ? 779 LEU   B O   1 
ATOM   6630 C  CB  . LEU   B 2 375 ? 41.71966 30.66565  77.85796  1.000 71.17696  ? 779 LEU   B CB  1 
ATOM   6631 C  CG  . LEU   B 2 375 ? 41.79921 29.23698  78.39719  1.000 72.44138  ? 779 LEU   B CG  1 
ATOM   6632 C  CD1 . LEU   B 2 375 ? 40.87232 29.06160  79.58938  1.000 79.22354  ? 779 LEU   B CD1 1 
ATOM   6633 C  CD2 . LEU   B 2 375 ? 41.46590 28.23394  77.30516  1.000 74.44471  ? 779 LEU   B CD2 1 
ATOM   6634 N  N   . LEU   B 2 376 ? 41.55946 32.38981  75.05375  1.000 63.49642  ? 780 LEU   B N   1 
ATOM   6635 C  CA  . LEU   B 2 376 ? 41.06486 33.61162  74.43651  1.000 67.76369  ? 780 LEU   B CA  1 
ATOM   6636 C  C   . LEU   B 2 376 ? 39.54241 33.59335  74.40757  1.000 70.35862  ? 780 LEU   B C   1 
ATOM   6637 O  O   . LEU   B 2 376 ? 38.92180 32.53020  74.32548  1.000 73.90622  ? 780 LEU   B O   1 
ATOM   6638 C  CB  . LEU   B 2 376 ? 41.61235 33.78120  73.01394  1.000 69.35351  ? 780 LEU   B CB  1 
ATOM   6639 C  CG  . LEU   B 2 376 ? 43.13539 33.80911  72.87109  1.000 67.88750  ? 780 LEU   B CG  1 
ATOM   6640 C  CD1 . LEU   B 2 376 ? 43.53383 34.09680  71.43189  1.000 72.15808  ? 780 LEU   B CD1 1 
ATOM   6641 C  CD2 . LEU   B 2 376 ? 43.74749 34.83090  73.81611  1.000 73.84667  ? 780 LEU   B CD2 1 
ATOM   6642 N  N   . PHE   B 2 377 ? 38.93827 34.77822  74.48178  1.000 65.93265  ? 781 PHE   B N   1 
ATOM   6643 C  CA  . PHE   B 2 377 ? 37.48414 34.87991  74.46865  1.000 67.29237  ? 781 PHE   B CA  1 
ATOM   6644 C  C   . PHE   B 2 377 ? 37.05959 36.01796  73.55321  1.000 71.57449  ? 781 PHE   B C   1 
ATOM   6645 O  O   . PHE   B 2 377 ? 37.60551 37.12179  73.63856  1.000 78.55027  ? 781 PHE   B O   1 
ATOM   6646 C  CB  . PHE   B 2 377 ? 36.93874 35.09290  75.88632  1.000 68.73132  ? 781 PHE   B CB  1 
ATOM   6647 C  CG  . PHE   B 2 377 ? 37.34868 34.02001  76.85974  1.000 66.67189  ? 781 PHE   B CG  1 
ATOM   6648 C  CD1 . PHE   B 2 377 ? 38.54868 34.10996  77.54822  1.000 66.10686  ? 781 PHE   B CD1 1 
ATOM   6649 C  CD2 . PHE   B 2 377 ? 36.53740 32.91982  77.08218  1.000 65.10771  ? 781 PHE   B CD2 1 
ATOM   6650 C  CE1 . PHE   B 2 377 ? 38.93107 33.12587  78.43947  1.000 67.71016  ? 781 PHE   B CE1 1 
ATOM   6651 C  CE2 . PHE   B 2 377 ? 36.91398 31.93201  77.97443  1.000 61.87449  ? 781 PHE   B CE2 1 
ATOM   6652 C  CZ  . PHE   B 2 377 ? 38.11239 32.03563  78.65337  1.000 63.93451  ? 781 PHE   B CZ  1 
ATOM   6653 N  N   . TYR   B 2 378 ? 36.08928 35.74568  72.67955  1.000 76.50810  ? 782 TYR   B N   1 
ATOM   6654 C  CA  . TYR   B 2 378 ? 35.61522 36.72135  71.69972  1.000 80.72660  ? 782 TYR   B CA  1 
ATOM   6655 C  C   . TYR   B 2 378 ? 34.09775 36.81206  71.76897  1.000 83.61687  ? 782 TYR   B C   1 
ATOM   6656 O  O   . TYR   B 2 378 ? 33.40924 35.80898  71.57075  1.000 88.68277  ? 782 TYR   B O   1 
ATOM   6657 C  CB  . TYR   B 2 378 ? 36.05407 36.33853  70.28126  1.000 83.31738  ? 782 TYR   B CB  1 
ATOM   6658 C  CG  . TYR   B 2 378 ? 37.52525 36.54501  69.99261  1.000 82.65788  ? 782 TYR   B CG  1 
ATOM   6659 C  CD1 . TYR   B 2 378 ? 38.48742 35.70646  70.54079  1.000 83.96051  ? 782 TYR   B CD1 1 
ATOM   6660 C  CD2 . TYR   B 2 378 ? 37.94956 37.56651  69.15293  1.000 79.55615  ? 782 TYR   B CD2 1 
ATOM   6661 C  CE1 . TYR   B 2 378 ? 39.83157 35.88969  70.27429  1.000 79.13480  ? 782 TYR   B CE1 1 
ATOM   6662 C  CE2 . TYR   B 2 378 ? 39.29147 37.75674  68.87906  1.000 83.59935  ? 782 TYR   B CE2 1 
ATOM   6663 C  CZ  . TYR   B 2 378 ? 40.22768 36.91558  69.44262  1.000 81.69728  ? 782 TYR   B CZ  1 
ATOM   6664 O  OH  . TYR   B 2 378 ? 41.56470 37.09999  69.17359  1.000 80.88278  ? 782 TYR   B OH  1 
ATOM   6665 N  N   . LYS   B 2 379 ? 33.57340 38.00590  72.02496  1.000 78.88514  ? 783 LYS   B N   1 
ATOM   6666 C  CA  . LYS   B 2 379 ? 32.13129 38.19773  72.08463  1.000 77.95931  ? 783 LYS   B CA  1 
ATOM   6667 C  C   . LYS   B 2 379 ? 31.61507 38.81725  70.78945  1.000 85.75587  ? 783 LYS   B C   1 
ATOM   6668 O  O   . LYS   B 2 379 ? 32.35065 39.47129  70.04597  1.000 86.80637  ? 783 LYS   B O   1 
ATOM   6669 C  CB  . LYS   B 2 379 ? 31.73884 39.07177  73.27979  1.000 76.29258  ? 783 LYS   B CB  1 
ATOM   6670 C  CG  . LYS   B 2 379 ? 31.96512 40.55970  73.08146  1.000 80.72828  ? 783 LYS   B CG  1 
ATOM   6671 C  CD  . LYS   B 2 379 ? 31.33307 41.35518  74.21269  1.000 78.89090  ? 783 LYS   B CD  1 
ATOM   6672 C  CE  . LYS   B 2 379 ? 31.46763 42.85121  73.98641  1.000 90.07491  ? 783 LYS   B CE  1 
ATOM   6673 N  NZ  . LYS   B 2 379 ? 30.81413 43.63354  75.07216  1.000 93.13142  ? 783 LYS   B NZ  1 
ATOM   6674 N  N   . LYS   B 2 380 ? 30.32768 38.59849  70.52889  1.000 90.18023  ? 784 LYS   B N   1 
ATOM   6675 C  CA  . LYS   B 2 380 ? 29.71756 39.07906  69.29636  1.000 91.21849  ? 784 LYS   B CA  1 
ATOM   6676 C  C   . LYS   B 2 380 ? 29.59956 40.59771  69.30736  1.000 90.59472  ? 784 LYS   B C   1 
ATOM   6677 O  O   . LYS   B 2 380 ? 29.21880 41.20227  70.31363  1.000 101.54591 ? 784 LYS   B O   1 
ATOM   6678 C  CB  . LYS   B 2 380 ? 28.34029 38.44344  69.10119  1.000 92.74784  ? 784 LYS   B CB  1 
ATOM   6679 C  CG  . LYS   B 2 380 ? 27.63366 38.87087  67.82263  1.000 96.55674  ? 784 LYS   B CG  1 
ATOM   6680 C  CD  . LYS   B 2 380 ? 26.32955 38.11420  67.62239  1.000 97.74601  ? 784 LYS   B CD  1 
ATOM   6681 C  CE  . LYS   B 2 380 ? 26.57699 36.62748  67.42432  1.000 94.42406  ? 784 LYS   B CE  1 
ATOM   6682 N  NZ  . LYS   B 2 380 ? 25.31441 35.88324  67.15998  1.000 102.97937 ? 784 LYS   B NZ  1 
ATOM   6683 N  N   . LEU   B 2 381 ? 29.92952 41.21220  68.17591  1.000 84.07685  ? 785 LEU   B N   1 
ATOM   6684 C  CA  . LEU   B 2 381 ? 29.88947 42.66334  68.04970  1.000 96.62295  ? 785 LEU   B CA  1 
ATOM   6685 C  C   . LEU   B 2 381 ? 28.65234 43.11396  67.27959  1.000 104.88033 ? 785 LEU   B C   1 
ATOM   6686 O  O   . LEU   B 2 381 ? 28.13062 44.20709  67.50090  1.000 99.71340  ? 785 LEU   B O   1 
ATOM   6687 C  CB  . LEU   B 2 381 ? 31.15491 43.17217  67.35769  1.000 93.15992  ? 785 LEU   B CB  1 
ATOM   6688 C  CG  . LEU   B 2 381 ? 32.48081 42.67138  67.93440  1.000 87.82496  ? 785 LEU   B CG  1 
ATOM   6689 C  CD1 . LEU   B 2 381 ? 33.65665 43.27848  67.18476  1.000 88.34852  ? 785 LEU   B CD1 1 
ATOM   6690 C  CD2 . LEU   B 2 381 ? 32.57230 42.97385  69.42235  1.000 89.00716  ? 785 LEU   B CD2 1 
ATOM   6691 O  OXT . LEU   B 2 381 ? 28.14545 42.39428  66.41853  1.000 104.08883 ? 785 LEU   B OXT 1 
HETATM 6692 ZN ZN  . ZN    C 3 .   ? 31.18775 9.50878   45.10956  1.000 70.56118  ? 801 ZN    B ZN  1 
HETATM 6693 C  C5  . A1BWW D 4 .   ? 34.81291 37.08909  89.79331  1.000 73.96276  ? 802 A1BWW B C5  1 
HETATM 6694 C  C7  . A1BWW D 4 .   ? 36.46369 37.15674  91.40073  1.000 80.56154  ? 802 A1BWW B C7  1 
HETATM 6695 C  C8  . A1BWW D 4 .   ? 37.17723 36.48055  92.54343  1.000 73.49627  ? 802 A1BWW B C8  1 
HETATM 6696 C  C10 . A1BWW D 4 .   ? 37.94611 35.19528  92.22905  1.000 74.73076  ? 802 A1BWW B C10 1 
HETATM 6697 C  C15 . A1BWW D 4 .   ? 39.94089 40.66793  92.61001  1.000 76.74518  ? 802 A1BWW B C15 1 
HETATM 6698 C  C17 . A1BWW D 4 .   ? 39.93548 42.67306  93.61269  1.000 83.20735  ? 802 A1BWW B C17 1 
HETATM 6699 C  C20 . A1BWW D 4 .   ? 37.28421 44.27138  92.34637  1.000 81.06166  ? 802 A1BWW B C20 1 
HETATM 6700 C  C21 . A1BWW D 4 .   ? 37.07978 45.62701  92.53944  1.000 89.57713  ? 802 A1BWW B C21 1 
HETATM 6701 C  C22 . A1BWW D 4 .   ? 36.89586 46.46285  91.45536  1.000 90.78147  ? 802 A1BWW B C22 1 
HETATM 6702 C  C24 . A1BWW D 4 .   ? 37.12033 44.57459  89.97419  1.000 83.26646  ? 802 A1BWW B C24 1 
HETATM 6703 C  C26 . A1BWW D 4 .   ? 36.72120 46.81693  88.97858  1.000 86.49975  ? 802 A1BWW B C26 1 
HETATM 6704 C  C28 . A1BWW D 4 .   ? 35.87301 47.62878  87.15742  1.000 89.15965  ? 802 A1BWW B C28 1 
HETATM 6705 C  C1  . A1BWW D 4 .   ? 35.71297 40.69453  88.28732  1.000 74.65587  ? 802 A1BWW B C1  1 
HETATM 6706 C  C11 . A1BWW D 4 .   ? 36.83540 38.42701  90.94958  1.000 79.31956  ? 802 A1BWW B C11 1 
HETATM 6707 C  C12 . A1BWW D 4 .   ? 37.94105 39.21513  91.54909  1.000 81.34112  ? 802 A1BWW B C12 1 
HETATM 6708 C  C14 . A1BWW D 4 .   ? 40.19381 39.42913  92.03330  1.000 77.75034  ? 802 A1BWW B C14 1 
HETATM 6709 C  C18 . A1BWW D 4 .   ? 38.65211 42.44372  93.27807  1.000 80.03383  ? 802 A1BWW B C18 1 
HETATM 6710 C  C19 . A1BWW D 4 .   ? 37.48257 43.36122  93.53283  1.000 79.55555  ? 802 A1BWW B C19 1 
HETATM 6711 C  C23 . A1BWW D 4 .   ? 36.91709 45.94235  90.15930  1.000 82.47098  ? 802 A1BWW B C23 1 
HETATM 6712 C  C25 . A1BWW D 4 .   ? 37.30197 43.74893  91.06478  1.000 78.08210  ? 802 A1BWW B C25 1 
HETATM 6713 C  C29 . A1BWW D 4 .   ? 36.94773 48.38674  87.45359  1.000 94.35390  ? 802 A1BWW B C29 1 
HETATM 6714 C  C3  . A1BWW D 4 .   ? 36.11501 38.97889  89.87858  1.000 74.14928  ? 802 A1BWW B C3  1 
HETATM 6715 C  C31 . A1BWW D 4 .   ? 38.68444 48.40258  89.28353  1.000 99.03128  ? 802 A1BWW B C31 1 
HETATM 6716 C  C32 . A1BWW D 4 .   ? 34.96027 47.81663  85.97276  1.000 84.21245  ? 802 A1BWW B C32 1 
HETATM 6717 C  C36 . A1BWW D 4 .   ? 38.61131 41.14140  92.61924  1.000 79.15239  ? 802 A1BWW B C36 1 
HETATM 6718 C  C9  . A1BWW D 4 .   ? 36.63656 35.13015  93.01690  1.000 73.35794  ? 802 A1BWW B C9  1 
HETATM 6719 F  F33 . A1BWW D 4 .   ? 34.35318 46.59745  85.65393  1.000 83.25991  ? 802 A1BWW B F33 1 
HETATM 6720 F  F34 . A1BWW D 4 .   ? 35.70572 48.26314  84.87664  1.000 83.00438  ? 802 A1BWW B F34 1 
HETATM 6721 F  F35 . A1BWW D 4 .   ? 33.97654 48.76089  86.28172  1.000 90.86823  ? 802 A1BWW B F35 1 
HETATM 6722 N  N13 . A1BWW D 4 .   ? 39.18734 38.74812  91.51412  1.000 80.89389  ? 802 A1BWW B N13 1 
HETATM 6723 N  N16 . A1BWW D 4 .   ? 40.71671 41.62383  93.22185  1.000 78.82513  ? 802 A1BWW B N16 1 
HETATM 6724 N  N27 . A1BWW D 4 .   ? 35.75690 46.68197  88.09517  1.000 84.84974  ? 802 A1BWW B N27 1 
HETATM 6725 N  N30 . A1BWW D 4 .   ? 37.49503 47.88124  88.60271  1.000 98.16393  ? 802 A1BWW B N30 1 
HETATM 6726 N  N37 . A1BWW D 4 .   ? 37.65272 40.39336  92.07979  1.000 82.71450  ? 802 A1BWW B N37 1 
HETATM 6727 N  N4  . A1BWW D 4 .   ? 35.12429 38.28402  89.33529  1.000 66.60089  ? 802 A1BWW B N4  1 
HETATM 6728 N  N6  . A1BWW D 4 .   ? 35.46244 36.53526  90.79766  1.000 81.98149  ? 802 A1BWW B N6  1 
HETATM 6729 O  O2  . A1BWW D 4 .   ? 36.44132 40.20708  89.41288  1.000 80.39139  ? 802 A1BWW B O2  1 
HETATM 6730 O  O   . HOH   E 5 .   ? 18.71336 3.09955   12.88126  1.000 91.03660  ? 601 HOH   A O   1 
HETATM 6731 O  O   . HOH   E 5 .   ? 38.72775 14.01088  23.44127  1.000 47.34287  ? 602 HOH   A O   1 
HETATM 6732 O  O   . HOH   E 5 .   ? 36.59853 -29.41151 50.95410  1.000 32.06890  ? 603 HOH   A O   1 
HETATM 6733 O  O   . HOH   E 5 .   ? 20.36913 29.80731  26.79284  1.000 55.44801  ? 604 HOH   A O   1 
HETATM 6734 O  O   . HOH   E 5 .   ? 34.66021 -31.56151 32.40985  1.000 43.40279  ? 605 HOH   A O   1 
HETATM 6735 O  O   . HOH   E 5 .   ? 35.39155 -8.59218  33.26144  1.000 52.78618  ? 606 HOH   A O   1 
HETATM 6736 O  O   . HOH   E 5 .   ? 23.13910 3.20118   15.57415  1.000 82.79835  ? 607 HOH   A O   1 
HETATM 6737 O  O   . HOH   F 5 .   ? 35.25932 18.45799  75.38667  1.000 53.12377  ? 901 HOH   B O   1 
HETATM 6738 O  O   . HOH   F 5 .   ? 42.04154 20.18025  60.18895  1.000 76.40770  ? 902 HOH   B O   1 
HETATM 6739 O  O   . HOH   F 5 .   ? 26.54703 27.26773  101.85590 1.000 45.89790  ? 903 HOH   B O   1 
# 
