data_9N17
# 
_entry.id   9N17 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9N17         pdb_00009n17 10.2210/pdb9n17/pdb 
WWPDB D_1000290927 ?            ?                   
EMDB  EMD-48808    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'Structure model' 1 1 2025-05-21 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_last'               
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9N17 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain (Deletion 33Pro34Arg)' 
_pdbx_database_related.db_id          EMD-48808 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              james.rini@utoronto.ca 
_pdbx_contact_author.name_first         James 
_pdbx_contact_author.name_last          Rini 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0952-2409 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Jin, M.'    1 0009-0009-1155-9890 
'Rini, J.M.' 2 0000-0002-0952-2409 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                4158 
_citation.page_last                 4158 
_citation.title                     
;Human coronavirus HKU1 spike structures reveal the basis for sialoglycan specificity and carbohydrate-promoted conformational changes.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-59137-y 
_citation.pdbx_database_id_PubMed   40324974 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Jin, M.'           1  ? 
primary 'Hassan, Z.'        2  ? 
primary 'Li, Z.'            3  ? 
primary 'Liu, Y.'           4  ? 
primary 'Marakhovskaia, A.' 5  ? 
primary 'Wong, A.H.M.'      6  ? 
primary 'Forman, A.'        7  ? 
primary 'Nitz, M.'          8  ? 
primary 'Gilbert, M.'       9  ? 
primary 'Yu, H.'            10 ? 
primary 'Chen, X.'          11 ? 
primary 'Rini, J.M.'        12 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Spike glycoprotein' 150378.422 1 ? ? ? ? 
2 branched    man 
;alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
;
910.823    1 ? ? ? ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401    1 ? ? ? ? 
4 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208    6 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'S glycoprotein,E2,Peplomer protein' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;VIGDFNCTNFAINDLNTTVISEYVVDVSYGLGTYYILDRVYLNTTILFTGYFPKSGANFRDLSLKGTTYLSTLWYQKPFL
SDFNNGIFSRVKNTKLYVNKTLYSEFSTIVIGSVFINNSYTIVVQPHNGVLEITACQYTMCEYPHTICKSKGSSRNESWH
FDKSEPLCLFKKNFTYNVSTDWLYFHFYQERGTFYAYYADSGMPTTFLFSLYLGTLLSHYYVLPLTCNAISSNTDNETLQ
YWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGVYDLSGFTVKPVATVHRRIPDLPDCDIDKWLNN
FNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSIVLDKFAIPNSRRSDLQLGSSGFLQSSNYK
IDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSASC
PIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFL
GWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDSNG
NIIGFKDFVTNKTYNIFPCYAGRVSAAFHQNASSLALLYRNLKCSYVLNNISLTTQPYFDSYLGCVFNADNLTDYSVSSC
ALRMGSGFCVDYNSPSSSSSRRKRRSISASYRFVTFEPFNVSFVNDSIESVGGLYEIKIPTNFTIVGQEEFIQTNSPKVT
IDCSLFVCSNYAACHDLLSEYGTFCDNINSILDEVNGLLDTTQLHVADTLMQGVTLSSNLNTNLHFDVDNINFKSLVGCL
GPHCGSSSRSFFEDLLFDKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSESQISGYTTAATVAAMFPPW
SAAAGIPFSLNVQYRINGLGVTMDVLNKNQKLIATAFNNALLSIQNGFSAPNSALAKIQSVVNSNAQALNSLLQQLFNKF
GAISSSLQEILSRLDPPEAQVQIDRLINGRLTALNAYVSQQLSDISLVKFGAALAMEKVNECVKSQSPRINFCGNGNHIL
SLVQNAPYGLLFMHFSYKPISFKTVLVSPGLCISGDVGIAPKQGYFIKHNDHWMFTGSSYYYPEPISDKNVVFMNTCSVN
FTKAPLVYLNHSVPKLSDFESELSHWFKNQTSIAPNLTLNLHTINATFLDLYYEMNLIQESIKSLNNSYINLKDIGTYEM
YVKSGGYIPEAPRDGQAYVRKDGEWVLLSTFLNSGRAHHHHHHGAGGLNDIFEAQKIEWHEDTAAA
;
_entity_poly.pdbx_seq_one_letter_code_can   
;VIGDFNCTNFAINDLNTTVISEYVVDVSYGLGTYYILDRVYLNTTILFTGYFPKSGANFRDLSLKGTTYLSTLWYQKPFL
SDFNNGIFSRVKNTKLYVNKTLYSEFSTIVIGSVFINNSYTIVVQPHNGVLEITACQYTMCEYPHTICKSKGSSRNESWH
FDKSEPLCLFKKNFTYNVSTDWLYFHFYQERGTFYAYYADSGMPTTFLFSLYLGTLLSHYYVLPLTCNAISSNTDNETLQ
YWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGVYDLSGFTVKPVATVHRRIPDLPDCDIDKWLNN
FNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSIVLDKFAIPNSRRSDLQLGSSGFLQSSNYK
IDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSASC
PIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFL
GWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDSNG
NIIGFKDFVTNKTYNIFPCYAGRVSAAFHQNASSLALLYRNLKCSYVLNNISLTTQPYFDSYLGCVFNADNLTDYSVSSC
ALRMGSGFCVDYNSPSSSSSRRKRRSISASYRFVTFEPFNVSFVNDSIESVGGLYEIKIPTNFTIVGQEEFIQTNSPKVT
IDCSLFVCSNYAACHDLLSEYGTFCDNINSILDEVNGLLDTTQLHVADTLMQGVTLSSNLNTNLHFDVDNINFKSLVGCL
GPHCGSSSRSFFEDLLFDKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSESQISGYTTAATVAAMFPPW
SAAAGIPFSLNVQYRINGLGVTMDVLNKNQKLIATAFNNALLSIQNGFSAPNSALAKIQSVVNSNAQALNSLLQQLFNKF
GAISSSLQEILSRLDPPEAQVQIDRLINGRLTALNAYVSQQLSDISLVKFGAALAMEKVNECVKSQSPRINFCGNGNHIL
SLVQNAPYGLLFMHFSYKPISFKTVLVSPGLCISGDVGIAPKQGYFIKHNDHWMFTGSSYYYPEPISDKNVVFMNTCSVN
FTKAPLVYLNHSVPKLSDFESELSHWFKNQTSIAPNLTLNLHTINATFLDLYYEMNLIQESIKSLNNSYINLKDIGTYEM
YVKSGGYIPEAPRDGQAYVRKDGEWVLLSTFLNSGRAHHHHHHGAGGLNDIFEAQKIEWHEDTAAA
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    VAL n 
1 2    ILE n 
1 3    GLY n 
1 4    ASP n 
1 5    PHE n 
1 6    ASN n 
1 7    CYS n 
1 8    THR n 
1 9    ASN n 
1 10   PHE n 
1 11   ALA n 
1 12   ILE n 
1 13   ASN n 
1 14   ASP n 
1 15   LEU n 
1 16   ASN n 
1 17   THR n 
1 18   THR n 
1 19   VAL n 
1 20   ILE n 
1 21   SER n 
1 22   GLU n 
1 23   TYR n 
1 24   VAL n 
1 25   VAL n 
1 26   ASP n 
1 27   VAL n 
1 28   SER n 
1 29   TYR n 
1 30   GLY n 
1 31   LEU n 
1 32   GLY n 
1 33   THR n 
1 34   TYR n 
1 35   TYR n 
1 36   ILE n 
1 37   LEU n 
1 38   ASP n 
1 39   ARG n 
1 40   VAL n 
1 41   TYR n 
1 42   LEU n 
1 43   ASN n 
1 44   THR n 
1 45   THR n 
1 46   ILE n 
1 47   LEU n 
1 48   PHE n 
1 49   THR n 
1 50   GLY n 
1 51   TYR n 
1 52   PHE n 
1 53   PRO n 
1 54   LYS n 
1 55   SER n 
1 56   GLY n 
1 57   ALA n 
1 58   ASN n 
1 59   PHE n 
1 60   ARG n 
1 61   ASP n 
1 62   LEU n 
1 63   SER n 
1 64   LEU n 
1 65   LYS n 
1 66   GLY n 
1 67   THR n 
1 68   THR n 
1 69   TYR n 
1 70   LEU n 
1 71   SER n 
1 72   THR n 
1 73   LEU n 
1 74   TRP n 
1 75   TYR n 
1 76   GLN n 
1 77   LYS n 
1 78   PRO n 
1 79   PHE n 
1 80   LEU n 
1 81   SER n 
1 82   ASP n 
1 83   PHE n 
1 84   ASN n 
1 85   ASN n 
1 86   GLY n 
1 87   ILE n 
1 88   PHE n 
1 89   SER n 
1 90   ARG n 
1 91   VAL n 
1 92   LYS n 
1 93   ASN n 
1 94   THR n 
1 95   LYS n 
1 96   LEU n 
1 97   TYR n 
1 98   VAL n 
1 99   ASN n 
1 100  LYS n 
1 101  THR n 
1 102  LEU n 
1 103  TYR n 
1 104  SER n 
1 105  GLU n 
1 106  PHE n 
1 107  SER n 
1 108  THR n 
1 109  ILE n 
1 110  VAL n 
1 111  ILE n 
1 112  GLY n 
1 113  SER n 
1 114  VAL n 
1 115  PHE n 
1 116  ILE n 
1 117  ASN n 
1 118  ASN n 
1 119  SER n 
1 120  TYR n 
1 121  THR n 
1 122  ILE n 
1 123  VAL n 
1 124  VAL n 
1 125  GLN n 
1 126  PRO n 
1 127  HIS n 
1 128  ASN n 
1 129  GLY n 
1 130  VAL n 
1 131  LEU n 
1 132  GLU n 
1 133  ILE n 
1 134  THR n 
1 135  ALA n 
1 136  CYS n 
1 137  GLN n 
1 138  TYR n 
1 139  THR n 
1 140  MET n 
1 141  CYS n 
1 142  GLU n 
1 143  TYR n 
1 144  PRO n 
1 145  HIS n 
1 146  THR n 
1 147  ILE n 
1 148  CYS n 
1 149  LYS n 
1 150  SER n 
1 151  LYS n 
1 152  GLY n 
1 153  SER n 
1 154  SER n 
1 155  ARG n 
1 156  ASN n 
1 157  GLU n 
1 158  SER n 
1 159  TRP n 
1 160  HIS n 
1 161  PHE n 
1 162  ASP n 
1 163  LYS n 
1 164  SER n 
1 165  GLU n 
1 166  PRO n 
1 167  LEU n 
1 168  CYS n 
1 169  LEU n 
1 170  PHE n 
1 171  LYS n 
1 172  LYS n 
1 173  ASN n 
1 174  PHE n 
1 175  THR n 
1 176  TYR n 
1 177  ASN n 
1 178  VAL n 
1 179  SER n 
1 180  THR n 
1 181  ASP n 
1 182  TRP n 
1 183  LEU n 
1 184  TYR n 
1 185  PHE n 
1 186  HIS n 
1 187  PHE n 
1 188  TYR n 
1 189  GLN n 
1 190  GLU n 
1 191  ARG n 
1 192  GLY n 
1 193  THR n 
1 194  PHE n 
1 195  TYR n 
1 196  ALA n 
1 197  TYR n 
1 198  TYR n 
1 199  ALA n 
1 200  ASP n 
1 201  SER n 
1 202  GLY n 
1 203  MET n 
1 204  PRO n 
1 205  THR n 
1 206  THR n 
1 207  PHE n 
1 208  LEU n 
1 209  PHE n 
1 210  SER n 
1 211  LEU n 
1 212  TYR n 
1 213  LEU n 
1 214  GLY n 
1 215  THR n 
1 216  LEU n 
1 217  LEU n 
1 218  SER n 
1 219  HIS n 
1 220  TYR n 
1 221  TYR n 
1 222  VAL n 
1 223  LEU n 
1 224  PRO n 
1 225  LEU n 
1 226  THR n 
1 227  CYS n 
1 228  ASN n 
1 229  ALA n 
1 230  ILE n 
1 231  SER n 
1 232  SER n 
1 233  ASN n 
1 234  THR n 
1 235  ASP n 
1 236  ASN n 
1 237  GLU n 
1 238  THR n 
1 239  LEU n 
1 240  GLN n 
1 241  TYR n 
1 242  TRP n 
1 243  VAL n 
1 244  THR n 
1 245  PRO n 
1 246  LEU n 
1 247  SER n 
1 248  LYS n 
1 249  ARG n 
1 250  GLN n 
1 251  TYR n 
1 252  LEU n 
1 253  LEU n 
1 254  LYS n 
1 255  PHE n 
1 256  ASP n 
1 257  ASN n 
1 258  ARG n 
1 259  GLY n 
1 260  VAL n 
1 261  ILE n 
1 262  THR n 
1 263  ASN n 
1 264  ALA n 
1 265  VAL n 
1 266  ASP n 
1 267  CYS n 
1 268  SER n 
1 269  SER n 
1 270  SER n 
1 271  PHE n 
1 272  PHE n 
1 273  SER n 
1 274  GLU n 
1 275  ILE n 
1 276  GLN n 
1 277  CYS n 
1 278  LYS n 
1 279  THR n 
1 280  LYS n 
1 281  SER n 
1 282  LEU n 
1 283  LEU n 
1 284  PRO n 
1 285  ASN n 
1 286  THR n 
1 287  GLY n 
1 288  VAL n 
1 289  TYR n 
1 290  ASP n 
1 291  LEU n 
1 292  SER n 
1 293  GLY n 
1 294  PHE n 
1 295  THR n 
1 296  VAL n 
1 297  LYS n 
1 298  PRO n 
1 299  VAL n 
1 300  ALA n 
1 301  THR n 
1 302  VAL n 
1 303  HIS n 
1 304  ARG n 
1 305  ARG n 
1 306  ILE n 
1 307  PRO n 
1 308  ASP n 
1 309  LEU n 
1 310  PRO n 
1 311  ASP n 
1 312  CYS n 
1 313  ASP n 
1 314  ILE n 
1 315  ASP n 
1 316  LYS n 
1 317  TRP n 
1 318  LEU n 
1 319  ASN n 
1 320  ASN n 
1 321  PHE n 
1 322  ASN n 
1 323  VAL n 
1 324  PRO n 
1 325  SER n 
1 326  PRO n 
1 327  LEU n 
1 328  ASN n 
1 329  TRP n 
1 330  GLU n 
1 331  ARG n 
1 332  LYS n 
1 333  ILE n 
1 334  PHE n 
1 335  SER n 
1 336  ASN n 
1 337  CYS n 
1 338  ASN n 
1 339  PHE n 
1 340  ASN n 
1 341  LEU n 
1 342  SER n 
1 343  THR n 
1 344  LEU n 
1 345  LEU n 
1 346  ARG n 
1 347  LEU n 
1 348  VAL n 
1 349  HIS n 
1 350  THR n 
1 351  ASP n 
1 352  SER n 
1 353  PHE n 
1 354  SER n 
1 355  CYS n 
1 356  ASN n 
1 357  ASN n 
1 358  PHE n 
1 359  ASP n 
1 360  GLU n 
1 361  SER n 
1 362  LYS n 
1 363  ILE n 
1 364  TYR n 
1 365  GLY n 
1 366  SER n 
1 367  CYS n 
1 368  PHE n 
1 369  LYS n 
1 370  SER n 
1 371  ILE n 
1 372  VAL n 
1 373  LEU n 
1 374  ASP n 
1 375  LYS n 
1 376  PHE n 
1 377  ALA n 
1 378  ILE n 
1 379  PRO n 
1 380  ASN n 
1 381  SER n 
1 382  ARG n 
1 383  ARG n 
1 384  SER n 
1 385  ASP n 
1 386  LEU n 
1 387  GLN n 
1 388  LEU n 
1 389  GLY n 
1 390  SER n 
1 391  SER n 
1 392  GLY n 
1 393  PHE n 
1 394  LEU n 
1 395  GLN n 
1 396  SER n 
1 397  SER n 
1 398  ASN n 
1 399  TYR n 
1 400  LYS n 
1 401  ILE n 
1 402  ASP n 
1 403  THR n 
1 404  THR n 
1 405  SER n 
1 406  SER n 
1 407  SER n 
1 408  CYS n 
1 409  GLN n 
1 410  LEU n 
1 411  TYR n 
1 412  TYR n 
1 413  SER n 
1 414  LEU n 
1 415  PRO n 
1 416  ALA n 
1 417  ILE n 
1 418  ASN n 
1 419  VAL n 
1 420  THR n 
1 421  ILE n 
1 422  ASN n 
1 423  ASN n 
1 424  TYR n 
1 425  ASN n 
1 426  PRO n 
1 427  SER n 
1 428  SER n 
1 429  TRP n 
1 430  ASN n 
1 431  ARG n 
1 432  ARG n 
1 433  TYR n 
1 434  GLY n 
1 435  PHE n 
1 436  ASN n 
1 437  ASN n 
1 438  PHE n 
1 439  ASN n 
1 440  LEU n 
1 441  SER n 
1 442  SER n 
1 443  HIS n 
1 444  SER n 
1 445  VAL n 
1 446  VAL n 
1 447  TYR n 
1 448  SER n 
1 449  ARG n 
1 450  TYR n 
1 451  CYS n 
1 452  PHE n 
1 453  SER n 
1 454  VAL n 
1 455  ASN n 
1 456  ASN n 
1 457  THR n 
1 458  PHE n 
1 459  CYS n 
1 460  PRO n 
1 461  CYS n 
1 462  ALA n 
1 463  LYS n 
1 464  PRO n 
1 465  SER n 
1 466  PHE n 
1 467  ALA n 
1 468  SER n 
1 469  SER n 
1 470  CYS n 
1 471  LYS n 
1 472  SER n 
1 473  HIS n 
1 474  LYS n 
1 475  PRO n 
1 476  PRO n 
1 477  SER n 
1 478  ALA n 
1 479  SER n 
1 480  CYS n 
1 481  PRO n 
1 482  ILE n 
1 483  GLY n 
1 484  THR n 
1 485  ASN n 
1 486  TYR n 
1 487  ARG n 
1 488  SER n 
1 489  CYS n 
1 490  GLU n 
1 491  SER n 
1 492  THR n 
1 493  THR n 
1 494  VAL n 
1 495  LEU n 
1 496  ASP n 
1 497  HIS n 
1 498  THR n 
1 499  ASP n 
1 500  TRP n 
1 501  CYS n 
1 502  ARG n 
1 503  CYS n 
1 504  SER n 
1 505  CYS n 
1 506  LEU n 
1 507  PRO n 
1 508  ASP n 
1 509  PRO n 
1 510  ILE n 
1 511  THR n 
1 512  ALA n 
1 513  TYR n 
1 514  ASP n 
1 515  PRO n 
1 516  ARG n 
1 517  SER n 
1 518  CYS n 
1 519  SER n 
1 520  GLN n 
1 521  LYS n 
1 522  LYS n 
1 523  SER n 
1 524  LEU n 
1 525  VAL n 
1 526  GLY n 
1 527  VAL n 
1 528  GLY n 
1 529  GLU n 
1 530  HIS n 
1 531  CYS n 
1 532  ALA n 
1 533  GLY n 
1 534  PHE n 
1 535  GLY n 
1 536  VAL n 
1 537  ASP n 
1 538  GLU n 
1 539  GLU n 
1 540  LYS n 
1 541  CYS n 
1 542  GLY n 
1 543  VAL n 
1 544  LEU n 
1 545  ASP n 
1 546  GLY n 
1 547  SER n 
1 548  TYR n 
1 549  ASN n 
1 550  VAL n 
1 551  SER n 
1 552  CYS n 
1 553  LEU n 
1 554  CYS n 
1 555  SER n 
1 556  THR n 
1 557  ASP n 
1 558  ALA n 
1 559  PHE n 
1 560  LEU n 
1 561  GLY n 
1 562  TRP n 
1 563  SER n 
1 564  TYR n 
1 565  ASP n 
1 566  THR n 
1 567  CYS n 
1 568  VAL n 
1 569  SER n 
1 570  ASN n 
1 571  ASN n 
1 572  ARG n 
1 573  CYS n 
1 574  ASN n 
1 575  ILE n 
1 576  PHE n 
1 577  SER n 
1 578  ASN n 
1 579  PHE n 
1 580  ILE n 
1 581  LEU n 
1 582  ASN n 
1 583  GLY n 
1 584  ILE n 
1 585  ASN n 
1 586  SER n 
1 587  GLY n 
1 588  THR n 
1 589  THR n 
1 590  CYS n 
1 591  SER n 
1 592  ASN n 
1 593  ASP n 
1 594  LEU n 
1 595  LEU n 
1 596  GLN n 
1 597  PRO n 
1 598  ASN n 
1 599  THR n 
1 600  GLU n 
1 601  VAL n 
1 602  PHE n 
1 603  THR n 
1 604  ASP n 
1 605  VAL n 
1 606  CYS n 
1 607  VAL n 
1 608  ASP n 
1 609  TYR n 
1 610  ASP n 
1 611  LEU n 
1 612  TYR n 
1 613  GLY n 
1 614  ILE n 
1 615  THR n 
1 616  GLY n 
1 617  GLN n 
1 618  GLY n 
1 619  ILE n 
1 620  PHE n 
1 621  LYS n 
1 622  GLU n 
1 623  VAL n 
1 624  SER n 
1 625  ALA n 
1 626  VAL n 
1 627  TYR n 
1 628  TYR n 
1 629  ASN n 
1 630  SER n 
1 631  TRP n 
1 632  GLN n 
1 633  ASN n 
1 634  LEU n 
1 635  LEU n 
1 636  TYR n 
1 637  ASP n 
1 638  SER n 
1 639  ASN n 
1 640  GLY n 
1 641  ASN n 
1 642  ILE n 
1 643  ILE n 
1 644  GLY n 
1 645  PHE n 
1 646  LYS n 
1 647  ASP n 
1 648  PHE n 
1 649  VAL n 
1 650  THR n 
1 651  ASN n 
1 652  LYS n 
1 653  THR n 
1 654  TYR n 
1 655  ASN n 
1 656  ILE n 
1 657  PHE n 
1 658  PRO n 
1 659  CYS n 
1 660  TYR n 
1 661  ALA n 
1 662  GLY n 
1 663  ARG n 
1 664  VAL n 
1 665  SER n 
1 666  ALA n 
1 667  ALA n 
1 668  PHE n 
1 669  HIS n 
1 670  GLN n 
1 671  ASN n 
1 672  ALA n 
1 673  SER n 
1 674  SER n 
1 675  LEU n 
1 676  ALA n 
1 677  LEU n 
1 678  LEU n 
1 679  TYR n 
1 680  ARG n 
1 681  ASN n 
1 682  LEU n 
1 683  LYS n 
1 684  CYS n 
1 685  SER n 
1 686  TYR n 
1 687  VAL n 
1 688  LEU n 
1 689  ASN n 
1 690  ASN n 
1 691  ILE n 
1 692  SER n 
1 693  LEU n 
1 694  THR n 
1 695  THR n 
1 696  GLN n 
1 697  PRO n 
1 698  TYR n 
1 699  PHE n 
1 700  ASP n 
1 701  SER n 
1 702  TYR n 
1 703  LEU n 
1 704  GLY n 
1 705  CYS n 
1 706  VAL n 
1 707  PHE n 
1 708  ASN n 
1 709  ALA n 
1 710  ASP n 
1 711  ASN n 
1 712  LEU n 
1 713  THR n 
1 714  ASP n 
1 715  TYR n 
1 716  SER n 
1 717  VAL n 
1 718  SER n 
1 719  SER n 
1 720  CYS n 
1 721  ALA n 
1 722  LEU n 
1 723  ARG n 
1 724  MET n 
1 725  GLY n 
1 726  SER n 
1 727  GLY n 
1 728  PHE n 
1 729  CYS n 
1 730  VAL n 
1 731  ASP n 
1 732  TYR n 
1 733  ASN n 
1 734  SER n 
1 735  PRO n 
1 736  SER n 
1 737  SER n 
1 738  SER n 
1 739  SER n 
1 740  SER n 
1 741  ARG n 
1 742  ARG n 
1 743  LYS n 
1 744  ARG n 
1 745  ARG n 
1 746  SER n 
1 747  ILE n 
1 748  SER n 
1 749  ALA n 
1 750  SER n 
1 751  TYR n 
1 752  ARG n 
1 753  PHE n 
1 754  VAL n 
1 755  THR n 
1 756  PHE n 
1 757  GLU n 
1 758  PRO n 
1 759  PHE n 
1 760  ASN n 
1 761  VAL n 
1 762  SER n 
1 763  PHE n 
1 764  VAL n 
1 765  ASN n 
1 766  ASP n 
1 767  SER n 
1 768  ILE n 
1 769  GLU n 
1 770  SER n 
1 771  VAL n 
1 772  GLY n 
1 773  GLY n 
1 774  LEU n 
1 775  TYR n 
1 776  GLU n 
1 777  ILE n 
1 778  LYS n 
1 779  ILE n 
1 780  PRO n 
1 781  THR n 
1 782  ASN n 
1 783  PHE n 
1 784  THR n 
1 785  ILE n 
1 786  VAL n 
1 787  GLY n 
1 788  GLN n 
1 789  GLU n 
1 790  GLU n 
1 791  PHE n 
1 792  ILE n 
1 793  GLN n 
1 794  THR n 
1 795  ASN n 
1 796  SER n 
1 797  PRO n 
1 798  LYS n 
1 799  VAL n 
1 800  THR n 
1 801  ILE n 
1 802  ASP n 
1 803  CYS n 
1 804  SER n 
1 805  LEU n 
1 806  PHE n 
1 807  VAL n 
1 808  CYS n 
1 809  SER n 
1 810  ASN n 
1 811  TYR n 
1 812  ALA n 
1 813  ALA n 
1 814  CYS n 
1 815  HIS n 
1 816  ASP n 
1 817  LEU n 
1 818  LEU n 
1 819  SER n 
1 820  GLU n 
1 821  TYR n 
1 822  GLY n 
1 823  THR n 
1 824  PHE n 
1 825  CYS n 
1 826  ASP n 
1 827  ASN n 
1 828  ILE n 
1 829  ASN n 
1 830  SER n 
1 831  ILE n 
1 832  LEU n 
1 833  ASP n 
1 834  GLU n 
1 835  VAL n 
1 836  ASN n 
1 837  GLY n 
1 838  LEU n 
1 839  LEU n 
1 840  ASP n 
1 841  THR n 
1 842  THR n 
1 843  GLN n 
1 844  LEU n 
1 845  HIS n 
1 846  VAL n 
1 847  ALA n 
1 848  ASP n 
1 849  THR n 
1 850  LEU n 
1 851  MET n 
1 852  GLN n 
1 853  GLY n 
1 854  VAL n 
1 855  THR n 
1 856  LEU n 
1 857  SER n 
1 858  SER n 
1 859  ASN n 
1 860  LEU n 
1 861  ASN n 
1 862  THR n 
1 863  ASN n 
1 864  LEU n 
1 865  HIS n 
1 866  PHE n 
1 867  ASP n 
1 868  VAL n 
1 869  ASP n 
1 870  ASN n 
1 871  ILE n 
1 872  ASN n 
1 873  PHE n 
1 874  LYS n 
1 875  SER n 
1 876  LEU n 
1 877  VAL n 
1 878  GLY n 
1 879  CYS n 
1 880  LEU n 
1 881  GLY n 
1 882  PRO n 
1 883  HIS n 
1 884  CYS n 
1 885  GLY n 
1 886  SER n 
1 887  SER n 
1 888  SER n 
1 889  ARG n 
1 890  SER n 
1 891  PHE n 
1 892  PHE n 
1 893  GLU n 
1 894  ASP n 
1 895  LEU n 
1 896  LEU n 
1 897  PHE n 
1 898  ASP n 
1 899  LYS n 
1 900  VAL n 
1 901  LYS n 
1 902  LEU n 
1 903  SER n 
1 904  ASP n 
1 905  VAL n 
1 906  GLY n 
1 907  PHE n 
1 908  VAL n 
1 909  GLU n 
1 910  ALA n 
1 911  TYR n 
1 912  ASN n 
1 913  ASN n 
1 914  CYS n 
1 915  THR n 
1 916  GLY n 
1 917  GLY n 
1 918  SER n 
1 919  GLU n 
1 920  ILE n 
1 921  ARG n 
1 922  ASP n 
1 923  LEU n 
1 924  LEU n 
1 925  CYS n 
1 926  VAL n 
1 927  GLN n 
1 928  SER n 
1 929  PHE n 
1 930  ASN n 
1 931  GLY n 
1 932  ILE n 
1 933  LYS n 
1 934  VAL n 
1 935  LEU n 
1 936  PRO n 
1 937  PRO n 
1 938  ILE n 
1 939  LEU n 
1 940  SER n 
1 941  GLU n 
1 942  SER n 
1 943  GLN n 
1 944  ILE n 
1 945  SER n 
1 946  GLY n 
1 947  TYR n 
1 948  THR n 
1 949  THR n 
1 950  ALA n 
1 951  ALA n 
1 952  THR n 
1 953  VAL n 
1 954  ALA n 
1 955  ALA n 
1 956  MET n 
1 957  PHE n 
1 958  PRO n 
1 959  PRO n 
1 960  TRP n 
1 961  SER n 
1 962  ALA n 
1 963  ALA n 
1 964  ALA n 
1 965  GLY n 
1 966  ILE n 
1 967  PRO n 
1 968  PHE n 
1 969  SER n 
1 970  LEU n 
1 971  ASN n 
1 972  VAL n 
1 973  GLN n 
1 974  TYR n 
1 975  ARG n 
1 976  ILE n 
1 977  ASN n 
1 978  GLY n 
1 979  LEU n 
1 980  GLY n 
1 981  VAL n 
1 982  THR n 
1 983  MET n 
1 984  ASP n 
1 985  VAL n 
1 986  LEU n 
1 987  ASN n 
1 988  LYS n 
1 989  ASN n 
1 990  GLN n 
1 991  LYS n 
1 992  LEU n 
1 993  ILE n 
1 994  ALA n 
1 995  THR n 
1 996  ALA n 
1 997  PHE n 
1 998  ASN n 
1 999  ASN n 
1 1000 ALA n 
1 1001 LEU n 
1 1002 LEU n 
1 1003 SER n 
1 1004 ILE n 
1 1005 GLN n 
1 1006 ASN n 
1 1007 GLY n 
1 1008 PHE n 
1 1009 SER n 
1 1010 ALA n 
1 1011 PRO n 
1 1012 ASN n 
1 1013 SER n 
1 1014 ALA n 
1 1015 LEU n 
1 1016 ALA n 
1 1017 LYS n 
1 1018 ILE n 
1 1019 GLN n 
1 1020 SER n 
1 1021 VAL n 
1 1022 VAL n 
1 1023 ASN n 
1 1024 SER n 
1 1025 ASN n 
1 1026 ALA n 
1 1027 GLN n 
1 1028 ALA n 
1 1029 LEU n 
1 1030 ASN n 
1 1031 SER n 
1 1032 LEU n 
1 1033 LEU n 
1 1034 GLN n 
1 1035 GLN n 
1 1036 LEU n 
1 1037 PHE n 
1 1038 ASN n 
1 1039 LYS n 
1 1040 PHE n 
1 1041 GLY n 
1 1042 ALA n 
1 1043 ILE n 
1 1044 SER n 
1 1045 SER n 
1 1046 SER n 
1 1047 LEU n 
1 1048 GLN n 
1 1049 GLU n 
1 1050 ILE n 
1 1051 LEU n 
1 1052 SER n 
1 1053 ARG n 
1 1054 LEU n 
1 1055 ASP n 
1 1056 PRO n 
1 1057 PRO n 
1 1058 GLU n 
1 1059 ALA n 
1 1060 GLN n 
1 1061 VAL n 
1 1062 GLN n 
1 1063 ILE n 
1 1064 ASP n 
1 1065 ARG n 
1 1066 LEU n 
1 1067 ILE n 
1 1068 ASN n 
1 1069 GLY n 
1 1070 ARG n 
1 1071 LEU n 
1 1072 THR n 
1 1073 ALA n 
1 1074 LEU n 
1 1075 ASN n 
1 1076 ALA n 
1 1077 TYR n 
1 1078 VAL n 
1 1079 SER n 
1 1080 GLN n 
1 1081 GLN n 
1 1082 LEU n 
1 1083 SER n 
1 1084 ASP n 
1 1085 ILE n 
1 1086 SER n 
1 1087 LEU n 
1 1088 VAL n 
1 1089 LYS n 
1 1090 PHE n 
1 1091 GLY n 
1 1092 ALA n 
1 1093 ALA n 
1 1094 LEU n 
1 1095 ALA n 
1 1096 MET n 
1 1097 GLU n 
1 1098 LYS n 
1 1099 VAL n 
1 1100 ASN n 
1 1101 GLU n 
1 1102 CYS n 
1 1103 VAL n 
1 1104 LYS n 
1 1105 SER n 
1 1106 GLN n 
1 1107 SER n 
1 1108 PRO n 
1 1109 ARG n 
1 1110 ILE n 
1 1111 ASN n 
1 1112 PHE n 
1 1113 CYS n 
1 1114 GLY n 
1 1115 ASN n 
1 1116 GLY n 
1 1117 ASN n 
1 1118 HIS n 
1 1119 ILE n 
1 1120 LEU n 
1 1121 SER n 
1 1122 LEU n 
1 1123 VAL n 
1 1124 GLN n 
1 1125 ASN n 
1 1126 ALA n 
1 1127 PRO n 
1 1128 TYR n 
1 1129 GLY n 
1 1130 LEU n 
1 1131 LEU n 
1 1132 PHE n 
1 1133 MET n 
1 1134 HIS n 
1 1135 PHE n 
1 1136 SER n 
1 1137 TYR n 
1 1138 LYS n 
1 1139 PRO n 
1 1140 ILE n 
1 1141 SER n 
1 1142 PHE n 
1 1143 LYS n 
1 1144 THR n 
1 1145 VAL n 
1 1146 LEU n 
1 1147 VAL n 
1 1148 SER n 
1 1149 PRO n 
1 1150 GLY n 
1 1151 LEU n 
1 1152 CYS n 
1 1153 ILE n 
1 1154 SER n 
1 1155 GLY n 
1 1156 ASP n 
1 1157 VAL n 
1 1158 GLY n 
1 1159 ILE n 
1 1160 ALA n 
1 1161 PRO n 
1 1162 LYS n 
1 1163 GLN n 
1 1164 GLY n 
1 1165 TYR n 
1 1166 PHE n 
1 1167 ILE n 
1 1168 LYS n 
1 1169 HIS n 
1 1170 ASN n 
1 1171 ASP n 
1 1172 HIS n 
1 1173 TRP n 
1 1174 MET n 
1 1175 PHE n 
1 1176 THR n 
1 1177 GLY n 
1 1178 SER n 
1 1179 SER n 
1 1180 TYR n 
1 1181 TYR n 
1 1182 TYR n 
1 1183 PRO n 
1 1184 GLU n 
1 1185 PRO n 
1 1186 ILE n 
1 1187 SER n 
1 1188 ASP n 
1 1189 LYS n 
1 1190 ASN n 
1 1191 VAL n 
1 1192 VAL n 
1 1193 PHE n 
1 1194 MET n 
1 1195 ASN n 
1 1196 THR n 
1 1197 CYS n 
1 1198 SER n 
1 1199 VAL n 
1 1200 ASN n 
1 1201 PHE n 
1 1202 THR n 
1 1203 LYS n 
1 1204 ALA n 
1 1205 PRO n 
1 1206 LEU n 
1 1207 VAL n 
1 1208 TYR n 
1 1209 LEU n 
1 1210 ASN n 
1 1211 HIS n 
1 1212 SER n 
1 1213 VAL n 
1 1214 PRO n 
1 1215 LYS n 
1 1216 LEU n 
1 1217 SER n 
1 1218 ASP n 
1 1219 PHE n 
1 1220 GLU n 
1 1221 SER n 
1 1222 GLU n 
1 1223 LEU n 
1 1224 SER n 
1 1225 HIS n 
1 1226 TRP n 
1 1227 PHE n 
1 1228 LYS n 
1 1229 ASN n 
1 1230 GLN n 
1 1231 THR n 
1 1232 SER n 
1 1233 ILE n 
1 1234 ALA n 
1 1235 PRO n 
1 1236 ASN n 
1 1237 LEU n 
1 1238 THR n 
1 1239 LEU n 
1 1240 ASN n 
1 1241 LEU n 
1 1242 HIS n 
1 1243 THR n 
1 1244 ILE n 
1 1245 ASN n 
1 1246 ALA n 
1 1247 THR n 
1 1248 PHE n 
1 1249 LEU n 
1 1250 ASP n 
1 1251 LEU n 
1 1252 TYR n 
1 1253 TYR n 
1 1254 GLU n 
1 1255 MET n 
1 1256 ASN n 
1 1257 LEU n 
1 1258 ILE n 
1 1259 GLN n 
1 1260 GLU n 
1 1261 SER n 
1 1262 ILE n 
1 1263 LYS n 
1 1264 SER n 
1 1265 LEU n 
1 1266 ASN n 
1 1267 ASN n 
1 1268 SER n 
1 1269 TYR n 
1 1270 ILE n 
1 1271 ASN n 
1 1272 LEU n 
1 1273 LYS n 
1 1274 ASP n 
1 1275 ILE n 
1 1276 GLY n 
1 1277 THR n 
1 1278 TYR n 
1 1279 GLU n 
1 1280 MET n 
1 1281 TYR n 
1 1282 VAL n 
1 1283 LYS n 
1 1284 SER n 
1 1285 GLY n 
1 1286 GLY n 
1 1287 TYR n 
1 1288 ILE n 
1 1289 PRO n 
1 1290 GLU n 
1 1291 ALA n 
1 1292 PRO n 
1 1293 ARG n 
1 1294 ASP n 
1 1295 GLY n 
1 1296 GLN n 
1 1297 ALA n 
1 1298 TYR n 
1 1299 VAL n 
1 1300 ARG n 
1 1301 LYS n 
1 1302 ASP n 
1 1303 GLY n 
1 1304 GLU n 
1 1305 TRP n 
1 1306 VAL n 
1 1307 LEU n 
1 1308 LEU n 
1 1309 SER n 
1 1310 THR n 
1 1311 PHE n 
1 1312 LEU n 
1 1313 ASN n 
1 1314 SER n 
1 1315 GLY n 
1 1316 ARG n 
1 1317 ALA n 
1 1318 HIS n 
1 1319 HIS n 
1 1320 HIS n 
1 1321 HIS n 
1 1322 HIS n 
1 1323 HIS n 
1 1324 GLY n 
1 1325 ALA n 
1 1326 GLY n 
1 1327 GLY n 
1 1328 LEU n 
1 1329 ASN n 
1 1330 ASP n 
1 1331 ILE n 
1 1332 PHE n 
1 1333 GLU n 
1 1334 ALA n 
1 1335 GLN n 
1 1336 LYS n 
1 1337 ILE n 
1 1338 GLU n 
1 1339 TRP n 
1 1340 HIS n 
1 1341 GLU n 
1 1342 ASP n 
1 1343 THR n 
1 1344 ALA n 
1 1345 ALA n 
1 1346 ALA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1346 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'S, 3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Human coronavirus HKU1' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     290028 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               human 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 'DManpa1-3[DManpa1-6]DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH'                                                   
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/3,5,4/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1122h-1a_1-5]/1-1-2-3-3/a4-b1_b4-c1_c3-d1_c6-e1' WURCS PDB2Glycan 
1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{[(3+1)][a-D-Manp]{}[(6+1)][a-D-Manp]{}}}}'    LINUCS PDB-CARE   
?     
4 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                                  
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1'                                                       WURCS PDB2Glycan 
1.1.0 
6 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'                                                             LINUCS PDB-CARE   
?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 2 4 MAN C1 O1 3 BMA O3 HO3 sing ? 
4 2 5 MAN C1 O1 3 BMA O6 HO6 sing ? 
5 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose                    'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6' 
180.156 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                         
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose              
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                       
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    VAL 1    14   14  VAL VAL A . n 
A 1 2    ILE 2    15   15  ILE ILE A . n 
A 1 3    GLY 3    16   16  GLY GLY A . n 
A 1 4    ASP 4    17   17  ASP ASP A . n 
A 1 5    PHE 5    18   18  PHE PHE A . n 
A 1 6    ASN 6    19   19  ASN ASN A . n 
A 1 7    CYS 7    20   20  CYS CYS A . n 
A 1 8    THR 8    21   21  THR THR A . n 
A 1 9    ASN 9    22   22  ASN ASN A . n 
A 1 10   PHE 10   23   23  PHE PHE A . n 
A 1 11   ALA 11   24   24  ALA ALA A . n 
A 1 12   ILE 12   25   25  ILE ILE A . n 
A 1 13   ASN 13   26   26  ASN ASN A . n 
A 1 14   ASP 14   27   27  ASP ASP A . n 
A 1 15   LEU 15   28   28  LEU LEU A . n 
A 1 16   ASN 16   29   29  ASN ASN A . n 
A 1 17   THR 17   30   30  THR THR A . n 
A 1 18   THR 18   31   31  THR THR A . n 
A 1 19   VAL 19   32   32  VAL VAL A . n 
A 1 20   ILE 20   35   35  ILE ILE A . n 
A 1 21   SER 21   36   36  SER SER A . n 
A 1 22   GLU 22   37   37  GLU GLU A . n 
A 1 23   TYR 23   38   38  TYR TYR A . n 
A 1 24   VAL 24   39   39  VAL VAL A . n 
A 1 25   VAL 25   40   40  VAL VAL A . n 
A 1 26   ASP 26   41   41  ASP ASP A . n 
A 1 27   VAL 27   42   42  VAL VAL A . n 
A 1 28   SER 28   43   43  SER SER A . n 
A 1 29   TYR 29   44   44  TYR TYR A . n 
A 1 30   GLY 30   45   45  GLY GLY A . n 
A 1 31   LEU 31   46   46  LEU LEU A . n 
A 1 32   GLY 32   47   47  GLY GLY A . n 
A 1 33   THR 33   48   48  THR THR A . n 
A 1 34   TYR 34   49   49  TYR TYR A . n 
A 1 35   TYR 35   50   50  TYR TYR A . n 
A 1 36   ILE 36   51   51  ILE ILE A . n 
A 1 37   LEU 37   52   52  LEU LEU A . n 
A 1 38   ASP 38   53   53  ASP ASP A . n 
A 1 39   ARG 39   54   54  ARG ARG A . n 
A 1 40   VAL 40   55   55  VAL VAL A . n 
A 1 41   TYR 41   56   56  TYR TYR A . n 
A 1 42   LEU 42   57   57  LEU LEU A . n 
A 1 43   ASN 43   58   58  ASN ASN A . n 
A 1 44   THR 44   59   59  THR THR A . n 
A 1 45   THR 45   60   60  THR THR A . n 
A 1 46   ILE 46   61   61  ILE ILE A . n 
A 1 47   LEU 47   62   62  LEU LEU A . n 
A 1 48   PHE 48   63   63  PHE PHE A . n 
A 1 49   THR 49   64   64  THR THR A . n 
A 1 50   GLY 50   65   65  GLY GLY A . n 
A 1 51   TYR 51   66   66  TYR TYR A . n 
A 1 52   PHE 52   67   67  PHE PHE A . n 
A 1 53   PRO 53   68   68  PRO PRO A . n 
A 1 54   LYS 54   69   69  LYS LYS A . n 
A 1 55   SER 55   70   70  SER SER A . n 
A 1 56   GLY 56   71   71  GLY GLY A . n 
A 1 57   ALA 57   72   72  ALA ALA A . n 
A 1 58   ASN 58   73   73  ASN ASN A . n 
A 1 59   PHE 59   74   74  PHE PHE A . n 
A 1 60   ARG 60   75   75  ARG ARG A . n 
A 1 61   ASP 61   76   76  ASP ASP A . n 
A 1 62   LEU 62   77   77  LEU LEU A . n 
A 1 63   SER 63   78   78  SER SER A . n 
A 1 64   LEU 64   79   79  LEU LEU A . n 
A 1 65   LYS 65   80   80  LYS LYS A . n 
A 1 66   GLY 66   81   81  GLY GLY A . n 
A 1 67   THR 67   82   82  THR THR A . n 
A 1 68   THR 68   83   83  THR THR A . n 
A 1 69   TYR 69   84   84  TYR TYR A . n 
A 1 70   LEU 70   85   85  LEU LEU A . n 
A 1 71   SER 71   86   86  SER SER A . n 
A 1 72   THR 72   87   87  THR THR A . n 
A 1 73   LEU 73   88   88  LEU LEU A . n 
A 1 74   TRP 74   89   89  TRP TRP A . n 
A 1 75   TYR 75   90   90  TYR TYR A . n 
A 1 76   GLN 76   91   91  GLN GLN A . n 
A 1 77   LYS 77   92   92  LYS LYS A . n 
A 1 78   PRO 78   93   93  PRO PRO A . n 
A 1 79   PHE 79   94   94  PHE PHE A . n 
A 1 80   LEU 80   95   95  LEU LEU A . n 
A 1 81   SER 81   96   96  SER SER A . n 
A 1 82   ASP 82   97   97  ASP ASP A . n 
A 1 83   PHE 83   98   98  PHE PHE A . n 
A 1 84   ASN 84   99   99  ASN ASN A . n 
A 1 85   ASN 85   100  100 ASN ASN A . n 
A 1 86   GLY 86   101  101 GLY GLY A . n 
A 1 87   ILE 87   102  102 ILE ILE A . n 
A 1 88   PHE 88   103  103 PHE PHE A . n 
A 1 89   SER 89   104  104 SER SER A . n 
A 1 90   ARG 90   105  105 ARG ARG A . n 
A 1 91   VAL 91   106  106 VAL VAL A . n 
A 1 92   LYS 92   107  107 LYS LYS A . n 
A 1 93   ASN 93   108  108 ASN ASN A . n 
A 1 94   THR 94   109  109 THR THR A . n 
A 1 95   LYS 95   110  110 LYS LYS A . n 
A 1 96   LEU 96   111  111 LEU LEU A . n 
A 1 97   TYR 97   112  112 TYR TYR A . n 
A 1 98   VAL 98   113  113 VAL VAL A . n 
A 1 99   ASN 99   114  114 ASN ASN A . n 
A 1 100  LYS 100  115  115 LYS LYS A . n 
A 1 101  THR 101  116  116 THR THR A . n 
A 1 102  LEU 102  117  117 LEU LEU A . n 
A 1 103  TYR 103  118  118 TYR TYR A . n 
A 1 104  SER 104  119  119 SER SER A . n 
A 1 105  GLU 105  120  120 GLU GLU A . n 
A 1 106  PHE 106  121  121 PHE PHE A . n 
A 1 107  SER 107  122  122 SER SER A . n 
A 1 108  THR 108  123  123 THR THR A . n 
A 1 109  ILE 109  124  124 ILE ILE A . n 
A 1 110  VAL 110  125  125 VAL VAL A . n 
A 1 111  ILE 111  126  126 ILE ILE A . n 
A 1 112  GLY 112  127  127 GLY GLY A . n 
A 1 113  SER 113  128  128 SER SER A . n 
A 1 114  VAL 114  129  129 VAL VAL A . n 
A 1 115  PHE 115  130  130 PHE PHE A . n 
A 1 116  ILE 116  131  131 ILE ILE A . n 
A 1 117  ASN 117  132  132 ASN ASN A . n 
A 1 118  ASN 118  133  133 ASN ASN A . n 
A 1 119  SER 119  134  134 SER SER A . n 
A 1 120  TYR 120  135  135 TYR TYR A . n 
A 1 121  THR 121  136  136 THR THR A . n 
A 1 122  ILE 122  137  137 ILE ILE A . n 
A 1 123  VAL 123  138  138 VAL VAL A . n 
A 1 124  VAL 124  139  139 VAL VAL A . n 
A 1 125  GLN 125  140  140 GLN GLN A . n 
A 1 126  PRO 126  141  141 PRO PRO A . n 
A 1 127  HIS 127  142  142 HIS HIS A . n 
A 1 128  ASN 128  143  143 ASN ASN A . n 
A 1 129  GLY 129  144  144 GLY GLY A . n 
A 1 130  VAL 130  145  145 VAL VAL A . n 
A 1 131  LEU 131  146  146 LEU LEU A . n 
A 1 132  GLU 132  147  147 GLU GLU A . n 
A 1 133  ILE 133  148  148 ILE ILE A . n 
A 1 134  THR 134  149  149 THR THR A . n 
A 1 135  ALA 135  150  150 ALA ALA A . n 
A 1 136  CYS 136  151  151 CYS CYS A . n 
A 1 137  GLN 137  152  152 GLN GLN A . n 
A 1 138  TYR 138  153  153 TYR TYR A . n 
A 1 139  THR 139  154  154 THR THR A . n 
A 1 140  MET 140  155  155 MET MET A . n 
A 1 141  CYS 141  156  156 CYS CYS A . n 
A 1 142  GLU 142  157  157 GLU GLU A . n 
A 1 143  TYR 143  158  158 TYR TYR A . n 
A 1 144  PRO 144  159  159 PRO PRO A . n 
A 1 145  HIS 145  160  160 HIS HIS A . n 
A 1 146  THR 146  161  161 THR THR A . n 
A 1 147  ILE 147  162  162 ILE ILE A . n 
A 1 148  CYS 148  163  163 CYS CYS A . n 
A 1 149  LYS 149  164  164 LYS LYS A . n 
A 1 150  SER 150  165  165 SER SER A . n 
A 1 151  LYS 151  166  166 LYS LYS A . n 
A 1 152  GLY 152  167  167 GLY GLY A . n 
A 1 153  SER 153  168  168 SER SER A . n 
A 1 154  SER 154  169  169 SER SER A . n 
A 1 155  ARG 155  170  170 ARG ARG A . n 
A 1 156  ASN 156  171  171 ASN ASN A . n 
A 1 157  GLU 157  172  172 GLU GLU A . n 
A 1 158  SER 158  173  173 SER SER A . n 
A 1 159  TRP 159  174  174 TRP TRP A . n 
A 1 160  HIS 160  175  175 HIS HIS A . n 
A 1 161  PHE 161  176  176 PHE PHE A . n 
A 1 162  ASP 162  177  177 ASP ASP A . n 
A 1 163  LYS 163  178  178 LYS LYS A . n 
A 1 164  SER 164  179  179 SER SER A . n 
A 1 165  GLU 165  180  180 GLU GLU A . n 
A 1 166  PRO 166  181  181 PRO PRO A . n 
A 1 167  LEU 167  182  182 LEU LEU A . n 
A 1 168  CYS 168  183  183 CYS CYS A . n 
A 1 169  LEU 169  184  184 LEU LEU A . n 
A 1 170  PHE 170  185  185 PHE PHE A . n 
A 1 171  LYS 171  186  186 LYS LYS A . n 
A 1 172  LYS 172  187  187 LYS LYS A . n 
A 1 173  ASN 173  188  188 ASN ASN A . n 
A 1 174  PHE 174  189  189 PHE PHE A . n 
A 1 175  THR 175  190  190 THR THR A . n 
A 1 176  TYR 176  191  191 TYR TYR A . n 
A 1 177  ASN 177  192  192 ASN ASN A . n 
A 1 178  VAL 178  193  193 VAL VAL A . n 
A 1 179  SER 179  194  194 SER SER A . n 
A 1 180  THR 180  195  195 THR THR A . n 
A 1 181  ASP 181  196  196 ASP ASP A . n 
A 1 182  TRP 182  197  197 TRP TRP A . n 
A 1 183  LEU 183  198  198 LEU LEU A . n 
A 1 184  TYR 184  199  199 TYR TYR A . n 
A 1 185  PHE 185  200  200 PHE PHE A . n 
A 1 186  HIS 186  201  201 HIS HIS A . n 
A 1 187  PHE 187  202  202 PHE PHE A . n 
A 1 188  TYR 188  203  203 TYR TYR A . n 
A 1 189  GLN 189  204  204 GLN GLN A . n 
A 1 190  GLU 190  205  205 GLU GLU A . n 
A 1 191  ARG 191  206  206 ARG ARG A . n 
A 1 192  GLY 192  207  207 GLY GLY A . n 
A 1 193  THR 193  208  208 THR THR A . n 
A 1 194  PHE 194  209  209 PHE PHE A . n 
A 1 195  TYR 195  210  210 TYR TYR A . n 
A 1 196  ALA 196  211  211 ALA ALA A . n 
A 1 197  TYR 197  212  212 TYR TYR A . n 
A 1 198  TYR 198  213  213 TYR TYR A . n 
A 1 199  ALA 199  214  214 ALA ALA A . n 
A 1 200  ASP 200  215  215 ASP ASP A . n 
A 1 201  SER 201  216  216 SER SER A . n 
A 1 202  GLY 202  217  217 GLY GLY A . n 
A 1 203  MET 203  218  218 MET MET A . n 
A 1 204  PRO 204  219  219 PRO PRO A . n 
A 1 205  THR 205  220  220 THR THR A . n 
A 1 206  THR 206  221  221 THR THR A . n 
A 1 207  PHE 207  222  222 PHE PHE A . n 
A 1 208  LEU 208  223  223 LEU LEU A . n 
A 1 209  PHE 209  224  224 PHE PHE A . n 
A 1 210  SER 210  225  225 SER SER A . n 
A 1 211  LEU 211  226  226 LEU LEU A . n 
A 1 212  TYR 212  227  227 TYR TYR A . n 
A 1 213  LEU 213  228  228 LEU LEU A . n 
A 1 214  GLY 214  229  229 GLY GLY A . n 
A 1 215  THR 215  230  230 THR THR A . n 
A 1 216  LEU 216  231  231 LEU LEU A . n 
A 1 217  LEU 217  232  232 LEU LEU A . n 
A 1 218  SER 218  233  233 SER SER A . n 
A 1 219  HIS 219  234  234 HIS HIS A . n 
A 1 220  TYR 220  235  235 TYR TYR A . n 
A 1 221  TYR 221  236  236 TYR TYR A . n 
A 1 222  VAL 222  237  237 VAL VAL A . n 
A 1 223  LEU 223  238  238 LEU LEU A . n 
A 1 224  PRO 224  239  239 PRO PRO A . n 
A 1 225  LEU 225  240  240 LEU LEU A . n 
A 1 226  THR 226  241  241 THR THR A . n 
A 1 227  CYS 227  242  242 CYS CYS A . n 
A 1 228  ASN 228  243  243 ASN ASN A . n 
A 1 229  ALA 229  244  244 ALA ALA A . n 
A 1 230  ILE 230  245  245 ILE ILE A . n 
A 1 231  SER 231  246  246 SER SER A . n 
A 1 232  SER 232  247  247 SER SER A . n 
A 1 233  ASN 233  248  248 ASN ASN A . n 
A 1 234  THR 234  249  249 THR THR A . n 
A 1 235  ASP 235  250  250 ASP ASP A . n 
A 1 236  ASN 236  251  251 ASN ASN A . n 
A 1 237  GLU 237  252  252 GLU GLU A . n 
A 1 238  THR 238  253  253 THR THR A . n 
A 1 239  LEU 239  254  254 LEU LEU A . n 
A 1 240  GLN 240  255  255 GLN GLN A . n 
A 1 241  TYR 241  256  256 TYR TYR A . n 
A 1 242  TRP 242  257  257 TRP TRP A . n 
A 1 243  VAL 243  258  258 VAL VAL A . n 
A 1 244  THR 244  259  259 THR THR A . n 
A 1 245  PRO 245  260  260 PRO PRO A . n 
A 1 246  LEU 246  261  261 LEU LEU A . n 
A 1 247  SER 247  262  262 SER SER A . n 
A 1 248  LYS 248  263  263 LYS LYS A . n 
A 1 249  ARG 249  264  264 ARG ARG A . n 
A 1 250  GLN 250  265  265 GLN GLN A . n 
A 1 251  TYR 251  266  266 TYR TYR A . n 
A 1 252  LEU 252  267  267 LEU LEU A . n 
A 1 253  LEU 253  268  268 LEU LEU A . n 
A 1 254  LYS 254  269  269 LYS LYS A . n 
A 1 255  PHE 255  270  270 PHE PHE A . n 
A 1 256  ASP 256  271  271 ASP ASP A . n 
A 1 257  ASN 257  272  272 ASN ASN A . n 
A 1 258  ARG 258  273  273 ARG ARG A . n 
A 1 259  GLY 259  274  274 GLY GLY A . n 
A 1 260  VAL 260  275  275 VAL VAL A . n 
A 1 261  ILE 261  276  276 ILE ILE A . n 
A 1 262  THR 262  277  277 THR THR A . n 
A 1 263  ASN 263  278  278 ASN ASN A . n 
A 1 264  ALA 264  279  279 ALA ALA A . n 
A 1 265  VAL 265  280  280 VAL VAL A . n 
A 1 266  ASP 266  281  281 ASP ASP A . n 
A 1 267  CYS 267  282  282 CYS CYS A . n 
A 1 268  SER 268  283  283 SER SER A . n 
A 1 269  SER 269  284  ?   ?   ?   A . n 
A 1 270  SER 270  285  ?   ?   ?   A . n 
A 1 271  PHE 271  286  ?   ?   ?   A . n 
A 1 272  PHE 272  287  ?   ?   ?   A . n 
A 1 273  SER 273  288  ?   ?   ?   A . n 
A 1 274  GLU 274  289  ?   ?   ?   A . n 
A 1 275  ILE 275  290  ?   ?   ?   A . n 
A 1 276  GLN 276  291  ?   ?   ?   A . n 
A 1 277  CYS 277  292  ?   ?   ?   A . n 
A 1 278  LYS 278  293  ?   ?   ?   A . n 
A 1 279  THR 279  294  ?   ?   ?   A . n 
A 1 280  LYS 280  295  ?   ?   ?   A . n 
A 1 281  SER 281  296  ?   ?   ?   A . n 
A 1 282  LEU 282  297  ?   ?   ?   A . n 
A 1 283  LEU 283  298  ?   ?   ?   A . n 
A 1 284  PRO 284  299  ?   ?   ?   A . n 
A 1 285  ASN 285  300  ?   ?   ?   A . n 
A 1 286  THR 286  301  ?   ?   ?   A . n 
A 1 287  GLY 287  302  ?   ?   ?   A . n 
A 1 288  VAL 288  303  ?   ?   ?   A . n 
A 1 289  TYR 289  304  ?   ?   ?   A . n 
A 1 290  ASP 290  305  ?   ?   ?   A . n 
A 1 291  LEU 291  306  ?   ?   ?   A . n 
A 1 292  SER 292  307  ?   ?   ?   A . n 
A 1 293  GLY 293  308  ?   ?   ?   A . n 
A 1 294  PHE 294  309  ?   ?   ?   A . n 
A 1 295  THR 295  310  ?   ?   ?   A . n 
A 1 296  VAL 296  311  ?   ?   ?   A . n 
A 1 297  LYS 297  312  ?   ?   ?   A . n 
A 1 298  PRO 298  313  ?   ?   ?   A . n 
A 1 299  VAL 299  314  ?   ?   ?   A . n 
A 1 300  ALA 300  315  ?   ?   ?   A . n 
A 1 301  THR 301  316  ?   ?   ?   A . n 
A 1 302  VAL 302  317  ?   ?   ?   A . n 
A 1 303  HIS 303  318  ?   ?   ?   A . n 
A 1 304  ARG 304  319  ?   ?   ?   A . n 
A 1 305  ARG 305  320  ?   ?   ?   A . n 
A 1 306  ILE 306  321  ?   ?   ?   A . n 
A 1 307  PRO 307  322  ?   ?   ?   A . n 
A 1 308  ASP 308  323  ?   ?   ?   A . n 
A 1 309  LEU 309  324  ?   ?   ?   A . n 
A 1 310  PRO 310  325  ?   ?   ?   A . n 
A 1 311  ASP 311  326  ?   ?   ?   A . n 
A 1 312  CYS 312  327  ?   ?   ?   A . n 
A 1 313  ASP 313  328  ?   ?   ?   A . n 
A 1 314  ILE 314  329  ?   ?   ?   A . n 
A 1 315  ASP 315  330  ?   ?   ?   A . n 
A 1 316  LYS 316  331  ?   ?   ?   A . n 
A 1 317  TRP 317  332  ?   ?   ?   A . n 
A 1 318  LEU 318  333  ?   ?   ?   A . n 
A 1 319  ASN 319  334  ?   ?   ?   A . n 
A 1 320  ASN 320  335  ?   ?   ?   A . n 
A 1 321  PHE 321  336  ?   ?   ?   A . n 
A 1 322  ASN 322  337  ?   ?   ?   A . n 
A 1 323  VAL 323  338  ?   ?   ?   A . n 
A 1 324  PRO 324  339  ?   ?   ?   A . n 
A 1 325  SER 325  340  ?   ?   ?   A . n 
A 1 326  PRO 326  341  ?   ?   ?   A . n 
A 1 327  LEU 327  342  ?   ?   ?   A . n 
A 1 328  ASN 328  343  ?   ?   ?   A . n 
A 1 329  TRP 329  344  ?   ?   ?   A . n 
A 1 330  GLU 330  345  ?   ?   ?   A . n 
A 1 331  ARG 331  346  ?   ?   ?   A . n 
A 1 332  LYS 332  347  ?   ?   ?   A . n 
A 1 333  ILE 333  348  ?   ?   ?   A . n 
A 1 334  PHE 334  349  ?   ?   ?   A . n 
A 1 335  SER 335  350  ?   ?   ?   A . n 
A 1 336  ASN 336  351  ?   ?   ?   A . n 
A 1 337  CYS 337  352  ?   ?   ?   A . n 
A 1 338  ASN 338  353  ?   ?   ?   A . n 
A 1 339  PHE 339  354  ?   ?   ?   A . n 
A 1 340  ASN 340  355  ?   ?   ?   A . n 
A 1 341  LEU 341  356  ?   ?   ?   A . n 
A 1 342  SER 342  357  ?   ?   ?   A . n 
A 1 343  THR 343  358  ?   ?   ?   A . n 
A 1 344  LEU 344  359  ?   ?   ?   A . n 
A 1 345  LEU 345  360  ?   ?   ?   A . n 
A 1 346  ARG 346  361  ?   ?   ?   A . n 
A 1 347  LEU 347  362  ?   ?   ?   A . n 
A 1 348  VAL 348  363  ?   ?   ?   A . n 
A 1 349  HIS 349  364  ?   ?   ?   A . n 
A 1 350  THR 350  365  ?   ?   ?   A . n 
A 1 351  ASP 351  366  ?   ?   ?   A . n 
A 1 352  SER 352  367  ?   ?   ?   A . n 
A 1 353  PHE 353  368  ?   ?   ?   A . n 
A 1 354  SER 354  369  ?   ?   ?   A . n 
A 1 355  CYS 355  370  ?   ?   ?   A . n 
A 1 356  ASN 356  371  ?   ?   ?   A . n 
A 1 357  ASN 357  372  ?   ?   ?   A . n 
A 1 358  PHE 358  373  ?   ?   ?   A . n 
A 1 359  ASP 359  374  ?   ?   ?   A . n 
A 1 360  GLU 360  375  ?   ?   ?   A . n 
A 1 361  SER 361  376  ?   ?   ?   A . n 
A 1 362  LYS 362  377  ?   ?   ?   A . n 
A 1 363  ILE 363  378  ?   ?   ?   A . n 
A 1 364  TYR 364  379  ?   ?   ?   A . n 
A 1 365  GLY 365  380  ?   ?   ?   A . n 
A 1 366  SER 366  381  ?   ?   ?   A . n 
A 1 367  CYS 367  382  ?   ?   ?   A . n 
A 1 368  PHE 368  383  ?   ?   ?   A . n 
A 1 369  LYS 369  384  ?   ?   ?   A . n 
A 1 370  SER 370  385  ?   ?   ?   A . n 
A 1 371  ILE 371  386  ?   ?   ?   A . n 
A 1 372  VAL 372  387  ?   ?   ?   A . n 
A 1 373  LEU 373  388  ?   ?   ?   A . n 
A 1 374  ASP 374  389  ?   ?   ?   A . n 
A 1 375  LYS 375  390  ?   ?   ?   A . n 
A 1 376  PHE 376  391  ?   ?   ?   A . n 
A 1 377  ALA 377  392  ?   ?   ?   A . n 
A 1 378  ILE 378  393  ?   ?   ?   A . n 
A 1 379  PRO 379  394  ?   ?   ?   A . n 
A 1 380  ASN 380  395  ?   ?   ?   A . n 
A 1 381  SER 381  396  ?   ?   ?   A . n 
A 1 382  ARG 382  397  ?   ?   ?   A . n 
A 1 383  ARG 383  398  ?   ?   ?   A . n 
A 1 384  SER 384  399  ?   ?   ?   A . n 
A 1 385  ASP 385  400  ?   ?   ?   A . n 
A 1 386  LEU 386  401  ?   ?   ?   A . n 
A 1 387  GLN 387  402  ?   ?   ?   A . n 
A 1 388  LEU 388  403  ?   ?   ?   A . n 
A 1 389  GLY 389  404  ?   ?   ?   A . n 
A 1 390  SER 390  405  ?   ?   ?   A . n 
A 1 391  SER 391  406  ?   ?   ?   A . n 
A 1 392  GLY 392  407  ?   ?   ?   A . n 
A 1 393  PHE 393  408  ?   ?   ?   A . n 
A 1 394  LEU 394  409  ?   ?   ?   A . n 
A 1 395  GLN 395  410  ?   ?   ?   A . n 
A 1 396  SER 396  411  ?   ?   ?   A . n 
A 1 397  SER 397  412  ?   ?   ?   A . n 
A 1 398  ASN 398  413  ?   ?   ?   A . n 
A 1 399  TYR 399  414  ?   ?   ?   A . n 
A 1 400  LYS 400  415  ?   ?   ?   A . n 
A 1 401  ILE 401  416  ?   ?   ?   A . n 
A 1 402  ASP 402  417  ?   ?   ?   A . n 
A 1 403  THR 403  418  ?   ?   ?   A . n 
A 1 404  THR 404  419  ?   ?   ?   A . n 
A 1 405  SER 405  420  ?   ?   ?   A . n 
A 1 406  SER 406  421  ?   ?   ?   A . n 
A 1 407  SER 407  422  ?   ?   ?   A . n 
A 1 408  CYS 408  423  ?   ?   ?   A . n 
A 1 409  GLN 409  424  ?   ?   ?   A . n 
A 1 410  LEU 410  425  ?   ?   ?   A . n 
A 1 411  TYR 411  426  ?   ?   ?   A . n 
A 1 412  TYR 412  427  ?   ?   ?   A . n 
A 1 413  SER 413  428  ?   ?   ?   A . n 
A 1 414  LEU 414  429  ?   ?   ?   A . n 
A 1 415  PRO 415  430  ?   ?   ?   A . n 
A 1 416  ALA 416  431  ?   ?   ?   A . n 
A 1 417  ILE 417  432  ?   ?   ?   A . n 
A 1 418  ASN 418  433  ?   ?   ?   A . n 
A 1 419  VAL 419  434  ?   ?   ?   A . n 
A 1 420  THR 420  435  ?   ?   ?   A . n 
A 1 421  ILE 421  436  ?   ?   ?   A . n 
A 1 422  ASN 422  437  ?   ?   ?   A . n 
A 1 423  ASN 423  438  ?   ?   ?   A . n 
A 1 424  TYR 424  439  ?   ?   ?   A . n 
A 1 425  ASN 425  440  ?   ?   ?   A . n 
A 1 426  PRO 426  441  ?   ?   ?   A . n 
A 1 427  SER 427  442  ?   ?   ?   A . n 
A 1 428  SER 428  443  ?   ?   ?   A . n 
A 1 429  TRP 429  444  ?   ?   ?   A . n 
A 1 430  ASN 430  445  ?   ?   ?   A . n 
A 1 431  ARG 431  446  ?   ?   ?   A . n 
A 1 432  ARG 432  447  ?   ?   ?   A . n 
A 1 433  TYR 433  448  ?   ?   ?   A . n 
A 1 434  GLY 434  449  ?   ?   ?   A . n 
A 1 435  PHE 435  450  ?   ?   ?   A . n 
A 1 436  ASN 436  451  ?   ?   ?   A . n 
A 1 437  ASN 437  452  ?   ?   ?   A . n 
A 1 438  PHE 438  453  ?   ?   ?   A . n 
A 1 439  ASN 439  454  ?   ?   ?   A . n 
A 1 440  LEU 440  455  ?   ?   ?   A . n 
A 1 441  SER 441  456  ?   ?   ?   A . n 
A 1 442  SER 442  457  ?   ?   ?   A . n 
A 1 443  HIS 443  458  ?   ?   ?   A . n 
A 1 444  SER 444  459  ?   ?   ?   A . n 
A 1 445  VAL 445  460  ?   ?   ?   A . n 
A 1 446  VAL 446  461  ?   ?   ?   A . n 
A 1 447  TYR 447  462  ?   ?   ?   A . n 
A 1 448  SER 448  463  ?   ?   ?   A . n 
A 1 449  ARG 449  464  ?   ?   ?   A . n 
A 1 450  TYR 450  465  ?   ?   ?   A . n 
A 1 451  CYS 451  466  ?   ?   ?   A . n 
A 1 452  PHE 452  467  ?   ?   ?   A . n 
A 1 453  SER 453  468  ?   ?   ?   A . n 
A 1 454  VAL 454  469  ?   ?   ?   A . n 
A 1 455  ASN 455  470  ?   ?   ?   A . n 
A 1 456  ASN 456  471  ?   ?   ?   A . n 
A 1 457  THR 457  472  ?   ?   ?   A . n 
A 1 458  PHE 458  473  ?   ?   ?   A . n 
A 1 459  CYS 459  474  ?   ?   ?   A . n 
A 1 460  PRO 460  475  ?   ?   ?   A . n 
A 1 461  CYS 461  476  ?   ?   ?   A . n 
A 1 462  ALA 462  477  ?   ?   ?   A . n 
A 1 463  LYS 463  478  ?   ?   ?   A . n 
A 1 464  PRO 464  479  ?   ?   ?   A . n 
A 1 465  SER 465  480  ?   ?   ?   A . n 
A 1 466  PHE 466  481  ?   ?   ?   A . n 
A 1 467  ALA 467  482  ?   ?   ?   A . n 
A 1 468  SER 468  483  ?   ?   ?   A . n 
A 1 469  SER 469  484  ?   ?   ?   A . n 
A 1 470  CYS 470  485  ?   ?   ?   A . n 
A 1 471  LYS 471  486  ?   ?   ?   A . n 
A 1 472  SER 472  487  ?   ?   ?   A . n 
A 1 473  HIS 473  488  ?   ?   ?   A . n 
A 1 474  LYS 474  489  ?   ?   ?   A . n 
A 1 475  PRO 475  490  ?   ?   ?   A . n 
A 1 476  PRO 476  491  ?   ?   ?   A . n 
A 1 477  SER 477  492  ?   ?   ?   A . n 
A 1 478  ALA 478  493  ?   ?   ?   A . n 
A 1 479  SER 479  494  ?   ?   ?   A . n 
A 1 480  CYS 480  495  ?   ?   ?   A . n 
A 1 481  PRO 481  496  ?   ?   ?   A . n 
A 1 482  ILE 482  497  ?   ?   ?   A . n 
A 1 483  GLY 483  498  ?   ?   ?   A . n 
A 1 484  THR 484  499  ?   ?   ?   A . n 
A 1 485  ASN 485  500  ?   ?   ?   A . n 
A 1 486  TYR 486  501  ?   ?   ?   A . n 
A 1 487  ARG 487  502  ?   ?   ?   A . n 
A 1 488  SER 488  503  ?   ?   ?   A . n 
A 1 489  CYS 489  504  ?   ?   ?   A . n 
A 1 490  GLU 490  505  ?   ?   ?   A . n 
A 1 491  SER 491  506  ?   ?   ?   A . n 
A 1 492  THR 492  507  ?   ?   ?   A . n 
A 1 493  THR 493  508  ?   ?   ?   A . n 
A 1 494  VAL 494  509  ?   ?   ?   A . n 
A 1 495  LEU 495  510  ?   ?   ?   A . n 
A 1 496  ASP 496  511  ?   ?   ?   A . n 
A 1 497  HIS 497  512  ?   ?   ?   A . n 
A 1 498  THR 498  513  ?   ?   ?   A . n 
A 1 499  ASP 499  514  ?   ?   ?   A . n 
A 1 500  TRP 500  515  ?   ?   ?   A . n 
A 1 501  CYS 501  516  ?   ?   ?   A . n 
A 1 502  ARG 502  517  ?   ?   ?   A . n 
A 1 503  CYS 503  518  ?   ?   ?   A . n 
A 1 504  SER 504  519  ?   ?   ?   A . n 
A 1 505  CYS 505  520  ?   ?   ?   A . n 
A 1 506  LEU 506  521  ?   ?   ?   A . n 
A 1 507  PRO 507  522  ?   ?   ?   A . n 
A 1 508  ASP 508  523  ?   ?   ?   A . n 
A 1 509  PRO 509  524  ?   ?   ?   A . n 
A 1 510  ILE 510  525  ?   ?   ?   A . n 
A 1 511  THR 511  526  ?   ?   ?   A . n 
A 1 512  ALA 512  527  ?   ?   ?   A . n 
A 1 513  TYR 513  528  ?   ?   ?   A . n 
A 1 514  ASP 514  529  ?   ?   ?   A . n 
A 1 515  PRO 515  530  ?   ?   ?   A . n 
A 1 516  ARG 516  531  ?   ?   ?   A . n 
A 1 517  SER 517  532  ?   ?   ?   A . n 
A 1 518  CYS 518  533  ?   ?   ?   A . n 
A 1 519  SER 519  534  ?   ?   ?   A . n 
A 1 520  GLN 520  535  ?   ?   ?   A . n 
A 1 521  LYS 521  536  ?   ?   ?   A . n 
A 1 522  LYS 522  537  ?   ?   ?   A . n 
A 1 523  SER 523  538  ?   ?   ?   A . n 
A 1 524  LEU 524  539  ?   ?   ?   A . n 
A 1 525  VAL 525  540  ?   ?   ?   A . n 
A 1 526  GLY 526  541  ?   ?   ?   A . n 
A 1 527  VAL 527  542  ?   ?   ?   A . n 
A 1 528  GLY 528  543  ?   ?   ?   A . n 
A 1 529  GLU 529  544  ?   ?   ?   A . n 
A 1 530  HIS 530  545  ?   ?   ?   A . n 
A 1 531  CYS 531  546  ?   ?   ?   A . n 
A 1 532  ALA 532  547  ?   ?   ?   A . n 
A 1 533  GLY 533  548  ?   ?   ?   A . n 
A 1 534  PHE 534  549  ?   ?   ?   A . n 
A 1 535  GLY 535  550  ?   ?   ?   A . n 
A 1 536  VAL 536  551  ?   ?   ?   A . n 
A 1 537  ASP 537  552  ?   ?   ?   A . n 
A 1 538  GLU 538  553  ?   ?   ?   A . n 
A 1 539  GLU 539  554  ?   ?   ?   A . n 
A 1 540  LYS 540  555  ?   ?   ?   A . n 
A 1 541  CYS 541  556  ?   ?   ?   A . n 
A 1 542  GLY 542  557  ?   ?   ?   A . n 
A 1 543  VAL 543  558  ?   ?   ?   A . n 
A 1 544  LEU 544  559  ?   ?   ?   A . n 
A 1 545  ASP 545  560  ?   ?   ?   A . n 
A 1 546  GLY 546  561  ?   ?   ?   A . n 
A 1 547  SER 547  562  ?   ?   ?   A . n 
A 1 548  TYR 548  563  ?   ?   ?   A . n 
A 1 549  ASN 549  564  ?   ?   ?   A . n 
A 1 550  VAL 550  565  ?   ?   ?   A . n 
A 1 551  SER 551  566  ?   ?   ?   A . n 
A 1 552  CYS 552  567  ?   ?   ?   A . n 
A 1 553  LEU 553  568  ?   ?   ?   A . n 
A 1 554  CYS 554  569  ?   ?   ?   A . n 
A 1 555  SER 555  570  ?   ?   ?   A . n 
A 1 556  THR 556  571  ?   ?   ?   A . n 
A 1 557  ASP 557  572  ?   ?   ?   A . n 
A 1 558  ALA 558  573  ?   ?   ?   A . n 
A 1 559  PHE 559  574  ?   ?   ?   A . n 
A 1 560  LEU 560  575  ?   ?   ?   A . n 
A 1 561  GLY 561  576  ?   ?   ?   A . n 
A 1 562  TRP 562  577  ?   ?   ?   A . n 
A 1 563  SER 563  578  ?   ?   ?   A . n 
A 1 564  TYR 564  579  ?   ?   ?   A . n 
A 1 565  ASP 565  580  ?   ?   ?   A . n 
A 1 566  THR 566  581  ?   ?   ?   A . n 
A 1 567  CYS 567  582  ?   ?   ?   A . n 
A 1 568  VAL 568  583  ?   ?   ?   A . n 
A 1 569  SER 569  584  ?   ?   ?   A . n 
A 1 570  ASN 570  585  ?   ?   ?   A . n 
A 1 571  ASN 571  586  ?   ?   ?   A . n 
A 1 572  ARG 572  587  ?   ?   ?   A . n 
A 1 573  CYS 573  588  ?   ?   ?   A . n 
A 1 574  ASN 574  589  ?   ?   ?   A . n 
A 1 575  ILE 575  590  ?   ?   ?   A . n 
A 1 576  PHE 576  591  ?   ?   ?   A . n 
A 1 577  SER 577  592  ?   ?   ?   A . n 
A 1 578  ASN 578  593  ?   ?   ?   A . n 
A 1 579  PHE 579  594  ?   ?   ?   A . n 
A 1 580  ILE 580  595  ?   ?   ?   A . n 
A 1 581  LEU 581  596  ?   ?   ?   A . n 
A 1 582  ASN 582  597  ?   ?   ?   A . n 
A 1 583  GLY 583  598  ?   ?   ?   A . n 
A 1 584  ILE 584  599  ?   ?   ?   A . n 
A 1 585  ASN 585  600  ?   ?   ?   A . n 
A 1 586  SER 586  601  ?   ?   ?   A . n 
A 1 587  GLY 587  602  ?   ?   ?   A . n 
A 1 588  THR 588  603  ?   ?   ?   A . n 
A 1 589  THR 589  604  ?   ?   ?   A . n 
A 1 590  CYS 590  605  ?   ?   ?   A . n 
A 1 591  SER 591  606  ?   ?   ?   A . n 
A 1 592  ASN 592  607  ?   ?   ?   A . n 
A 1 593  ASP 593  608  ?   ?   ?   A . n 
A 1 594  LEU 594  609  ?   ?   ?   A . n 
A 1 595  LEU 595  610  ?   ?   ?   A . n 
A 1 596  GLN 596  611  ?   ?   ?   A . n 
A 1 597  PRO 597  612  ?   ?   ?   A . n 
A 1 598  ASN 598  613  ?   ?   ?   A . n 
A 1 599  THR 599  614  ?   ?   ?   A . n 
A 1 600  GLU 600  615  ?   ?   ?   A . n 
A 1 601  VAL 601  616  ?   ?   ?   A . n 
A 1 602  PHE 602  617  ?   ?   ?   A . n 
A 1 603  THR 603  618  ?   ?   ?   A . n 
A 1 604  ASP 604  619  ?   ?   ?   A . n 
A 1 605  VAL 605  620  ?   ?   ?   A . n 
A 1 606  CYS 606  621  ?   ?   ?   A . n 
A 1 607  VAL 607  622  ?   ?   ?   A . n 
A 1 608  ASP 608  623  ?   ?   ?   A . n 
A 1 609  TYR 609  624  ?   ?   ?   A . n 
A 1 610  ASP 610  625  ?   ?   ?   A . n 
A 1 611  LEU 611  626  ?   ?   ?   A . n 
A 1 612  TYR 612  627  ?   ?   ?   A . n 
A 1 613  GLY 613  628  ?   ?   ?   A . n 
A 1 614  ILE 614  629  ?   ?   ?   A . n 
A 1 615  THR 615  630  ?   ?   ?   A . n 
A 1 616  GLY 616  631  ?   ?   ?   A . n 
A 1 617  GLN 617  632  ?   ?   ?   A . n 
A 1 618  GLY 618  633  ?   ?   ?   A . n 
A 1 619  ILE 619  634  ?   ?   ?   A . n 
A 1 620  PHE 620  635  ?   ?   ?   A . n 
A 1 621  LYS 621  636  ?   ?   ?   A . n 
A 1 622  GLU 622  637  ?   ?   ?   A . n 
A 1 623  VAL 623  638  ?   ?   ?   A . n 
A 1 624  SER 624  639  ?   ?   ?   A . n 
A 1 625  ALA 625  640  ?   ?   ?   A . n 
A 1 626  VAL 626  641  ?   ?   ?   A . n 
A 1 627  TYR 627  642  ?   ?   ?   A . n 
A 1 628  TYR 628  643  ?   ?   ?   A . n 
A 1 629  ASN 629  644  ?   ?   ?   A . n 
A 1 630  SER 630  645  ?   ?   ?   A . n 
A 1 631  TRP 631  646  ?   ?   ?   A . n 
A 1 632  GLN 632  647  ?   ?   ?   A . n 
A 1 633  ASN 633  648  ?   ?   ?   A . n 
A 1 634  LEU 634  649  ?   ?   ?   A . n 
A 1 635  LEU 635  650  ?   ?   ?   A . n 
A 1 636  TYR 636  651  ?   ?   ?   A . n 
A 1 637  ASP 637  652  ?   ?   ?   A . n 
A 1 638  SER 638  653  ?   ?   ?   A . n 
A 1 639  ASN 639  654  ?   ?   ?   A . n 
A 1 640  GLY 640  655  ?   ?   ?   A . n 
A 1 641  ASN 641  656  ?   ?   ?   A . n 
A 1 642  ILE 642  657  ?   ?   ?   A . n 
A 1 643  ILE 643  658  ?   ?   ?   A . n 
A 1 644  GLY 644  659  ?   ?   ?   A . n 
A 1 645  PHE 645  660  ?   ?   ?   A . n 
A 1 646  LYS 646  661  ?   ?   ?   A . n 
A 1 647  ASP 647  662  ?   ?   ?   A . n 
A 1 648  PHE 648  663  ?   ?   ?   A . n 
A 1 649  VAL 649  664  ?   ?   ?   A . n 
A 1 650  THR 650  665  ?   ?   ?   A . n 
A 1 651  ASN 651  666  ?   ?   ?   A . n 
A 1 652  LYS 652  667  ?   ?   ?   A . n 
A 1 653  THR 653  668  ?   ?   ?   A . n 
A 1 654  TYR 654  669  ?   ?   ?   A . n 
A 1 655  ASN 655  670  ?   ?   ?   A . n 
A 1 656  ILE 656  671  ?   ?   ?   A . n 
A 1 657  PHE 657  672  ?   ?   ?   A . n 
A 1 658  PRO 658  673  ?   ?   ?   A . n 
A 1 659  CYS 659  674  ?   ?   ?   A . n 
A 1 660  TYR 660  675  ?   ?   ?   A . n 
A 1 661  ALA 661  676  ?   ?   ?   A . n 
A 1 662  GLY 662  677  ?   ?   ?   A . n 
A 1 663  ARG 663  678  ?   ?   ?   A . n 
A 1 664  VAL 664  679  ?   ?   ?   A . n 
A 1 665  SER 665  680  ?   ?   ?   A . n 
A 1 666  ALA 666  681  ?   ?   ?   A . n 
A 1 667  ALA 667  682  ?   ?   ?   A . n 
A 1 668  PHE 668  683  ?   ?   ?   A . n 
A 1 669  HIS 669  684  ?   ?   ?   A . n 
A 1 670  GLN 670  685  ?   ?   ?   A . n 
A 1 671  ASN 671  686  ?   ?   ?   A . n 
A 1 672  ALA 672  687  ?   ?   ?   A . n 
A 1 673  SER 673  688  ?   ?   ?   A . n 
A 1 674  SER 674  689  ?   ?   ?   A . n 
A 1 675  LEU 675  690  ?   ?   ?   A . n 
A 1 676  ALA 676  691  ?   ?   ?   A . n 
A 1 677  LEU 677  692  ?   ?   ?   A . n 
A 1 678  LEU 678  693  ?   ?   ?   A . n 
A 1 679  TYR 679  694  ?   ?   ?   A . n 
A 1 680  ARG 680  695  ?   ?   ?   A . n 
A 1 681  ASN 681  696  ?   ?   ?   A . n 
A 1 682  LEU 682  697  ?   ?   ?   A . n 
A 1 683  LYS 683  698  ?   ?   ?   A . n 
A 1 684  CYS 684  699  ?   ?   ?   A . n 
A 1 685  SER 685  700  ?   ?   ?   A . n 
A 1 686  TYR 686  701  ?   ?   ?   A . n 
A 1 687  VAL 687  702  ?   ?   ?   A . n 
A 1 688  LEU 688  703  ?   ?   ?   A . n 
A 1 689  ASN 689  704  ?   ?   ?   A . n 
A 1 690  ASN 690  705  ?   ?   ?   A . n 
A 1 691  ILE 691  706  ?   ?   ?   A . n 
A 1 692  SER 692  707  ?   ?   ?   A . n 
A 1 693  LEU 693  708  ?   ?   ?   A . n 
A 1 694  THR 694  709  ?   ?   ?   A . n 
A 1 695  THR 695  710  ?   ?   ?   A . n 
A 1 696  GLN 696  711  ?   ?   ?   A . n 
A 1 697  PRO 697  712  ?   ?   ?   A . n 
A 1 698  TYR 698  713  ?   ?   ?   A . n 
A 1 699  PHE 699  714  ?   ?   ?   A . n 
A 1 700  ASP 700  715  ?   ?   ?   A . n 
A 1 701  SER 701  716  ?   ?   ?   A . n 
A 1 702  TYR 702  717  ?   ?   ?   A . n 
A 1 703  LEU 703  718  ?   ?   ?   A . n 
A 1 704  GLY 704  719  ?   ?   ?   A . n 
A 1 705  CYS 705  720  ?   ?   ?   A . n 
A 1 706  VAL 706  721  ?   ?   ?   A . n 
A 1 707  PHE 707  722  ?   ?   ?   A . n 
A 1 708  ASN 708  723  ?   ?   ?   A . n 
A 1 709  ALA 709  724  ?   ?   ?   A . n 
A 1 710  ASP 710  725  ?   ?   ?   A . n 
A 1 711  ASN 711  726  ?   ?   ?   A . n 
A 1 712  LEU 712  727  ?   ?   ?   A . n 
A 1 713  THR 713  728  ?   ?   ?   A . n 
A 1 714  ASP 714  729  ?   ?   ?   A . n 
A 1 715  TYR 715  730  ?   ?   ?   A . n 
A 1 716  SER 716  731  ?   ?   ?   A . n 
A 1 717  VAL 717  732  ?   ?   ?   A . n 
A 1 718  SER 718  733  ?   ?   ?   A . n 
A 1 719  SER 719  734  ?   ?   ?   A . n 
A 1 720  CYS 720  735  ?   ?   ?   A . n 
A 1 721  ALA 721  736  ?   ?   ?   A . n 
A 1 722  LEU 722  737  ?   ?   ?   A . n 
A 1 723  ARG 723  738  ?   ?   ?   A . n 
A 1 724  MET 724  739  ?   ?   ?   A . n 
A 1 725  GLY 725  740  ?   ?   ?   A . n 
A 1 726  SER 726  741  ?   ?   ?   A . n 
A 1 727  GLY 727  742  ?   ?   ?   A . n 
A 1 728  PHE 728  743  ?   ?   ?   A . n 
A 1 729  CYS 729  744  ?   ?   ?   A . n 
A 1 730  VAL 730  745  ?   ?   ?   A . n 
A 1 731  ASP 731  746  ?   ?   ?   A . n 
A 1 732  TYR 732  747  ?   ?   ?   A . n 
A 1 733  ASN 733  748  ?   ?   ?   A . n 
A 1 734  SER 734  749  ?   ?   ?   A . n 
A 1 735  PRO 735  750  ?   ?   ?   A . n 
A 1 736  SER 736  751  ?   ?   ?   A . n 
A 1 737  SER 737  752  ?   ?   ?   A . n 
A 1 738  SER 738  753  ?   ?   ?   A . n 
A 1 739  SER 739  754  ?   ?   ?   A . n 
A 1 740  SER 740  755  ?   ?   ?   A . n 
A 1 741  ARG 741  756  ?   ?   ?   A . n 
A 1 742  ARG 742  757  ?   ?   ?   A . n 
A 1 743  LYS 743  758  ?   ?   ?   A . n 
A 1 744  ARG 744  759  ?   ?   ?   A . n 
A 1 745  ARG 745  760  ?   ?   ?   A . n 
A 1 746  SER 746  761  ?   ?   ?   A . n 
A 1 747  ILE 747  762  ?   ?   ?   A . n 
A 1 748  SER 748  763  ?   ?   ?   A . n 
A 1 749  ALA 749  764  ?   ?   ?   A . n 
A 1 750  SER 750  765  ?   ?   ?   A . n 
A 1 751  TYR 751  766  ?   ?   ?   A . n 
A 1 752  ARG 752  767  ?   ?   ?   A . n 
A 1 753  PHE 753  768  ?   ?   ?   A . n 
A 1 754  VAL 754  769  ?   ?   ?   A . n 
A 1 755  THR 755  770  ?   ?   ?   A . n 
A 1 756  PHE 756  771  ?   ?   ?   A . n 
A 1 757  GLU 757  772  ?   ?   ?   A . n 
A 1 758  PRO 758  773  ?   ?   ?   A . n 
A 1 759  PHE 759  774  ?   ?   ?   A . n 
A 1 760  ASN 760  775  ?   ?   ?   A . n 
A 1 761  VAL 761  776  ?   ?   ?   A . n 
A 1 762  SER 762  777  ?   ?   ?   A . n 
A 1 763  PHE 763  778  ?   ?   ?   A . n 
A 1 764  VAL 764  779  ?   ?   ?   A . n 
A 1 765  ASN 765  780  ?   ?   ?   A . n 
A 1 766  ASP 766  781  ?   ?   ?   A . n 
A 1 767  SER 767  782  ?   ?   ?   A . n 
A 1 768  ILE 768  783  ?   ?   ?   A . n 
A 1 769  GLU 769  784  ?   ?   ?   A . n 
A 1 770  SER 770  785  ?   ?   ?   A . n 
A 1 771  VAL 771  786  ?   ?   ?   A . n 
A 1 772  GLY 772  787  ?   ?   ?   A . n 
A 1 773  GLY 773  788  ?   ?   ?   A . n 
A 1 774  LEU 774  789  ?   ?   ?   A . n 
A 1 775  TYR 775  790  ?   ?   ?   A . n 
A 1 776  GLU 776  791  ?   ?   ?   A . n 
A 1 777  ILE 777  792  ?   ?   ?   A . n 
A 1 778  LYS 778  793  ?   ?   ?   A . n 
A 1 779  ILE 779  794  ?   ?   ?   A . n 
A 1 780  PRO 780  795  ?   ?   ?   A . n 
A 1 781  THR 781  796  ?   ?   ?   A . n 
A 1 782  ASN 782  797  ?   ?   ?   A . n 
A 1 783  PHE 783  798  ?   ?   ?   A . n 
A 1 784  THR 784  799  ?   ?   ?   A . n 
A 1 785  ILE 785  800  ?   ?   ?   A . n 
A 1 786  VAL 786  801  ?   ?   ?   A . n 
A 1 787  GLY 787  802  ?   ?   ?   A . n 
A 1 788  GLN 788  803  ?   ?   ?   A . n 
A 1 789  GLU 789  804  ?   ?   ?   A . n 
A 1 790  GLU 790  805  ?   ?   ?   A . n 
A 1 791  PHE 791  806  ?   ?   ?   A . n 
A 1 792  ILE 792  807  ?   ?   ?   A . n 
A 1 793  GLN 793  808  ?   ?   ?   A . n 
A 1 794  THR 794  809  ?   ?   ?   A . n 
A 1 795  ASN 795  810  ?   ?   ?   A . n 
A 1 796  SER 796  811  ?   ?   ?   A . n 
A 1 797  PRO 797  812  ?   ?   ?   A . n 
A 1 798  LYS 798  813  ?   ?   ?   A . n 
A 1 799  VAL 799  814  ?   ?   ?   A . n 
A 1 800  THR 800  815  ?   ?   ?   A . n 
A 1 801  ILE 801  816  ?   ?   ?   A . n 
A 1 802  ASP 802  817  ?   ?   ?   A . n 
A 1 803  CYS 803  818  ?   ?   ?   A . n 
A 1 804  SER 804  819  ?   ?   ?   A . n 
A 1 805  LEU 805  820  ?   ?   ?   A . n 
A 1 806  PHE 806  821  ?   ?   ?   A . n 
A 1 807  VAL 807  822  ?   ?   ?   A . n 
A 1 808  CYS 808  823  ?   ?   ?   A . n 
A 1 809  SER 809  824  ?   ?   ?   A . n 
A 1 810  ASN 810  825  ?   ?   ?   A . n 
A 1 811  TYR 811  826  ?   ?   ?   A . n 
A 1 812  ALA 812  827  ?   ?   ?   A . n 
A 1 813  ALA 813  828  ?   ?   ?   A . n 
A 1 814  CYS 814  829  ?   ?   ?   A . n 
A 1 815  HIS 815  830  ?   ?   ?   A . n 
A 1 816  ASP 816  831  ?   ?   ?   A . n 
A 1 817  LEU 817  832  ?   ?   ?   A . n 
A 1 818  LEU 818  833  ?   ?   ?   A . n 
A 1 819  SER 819  834  ?   ?   ?   A . n 
A 1 820  GLU 820  835  ?   ?   ?   A . n 
A 1 821  TYR 821  836  ?   ?   ?   A . n 
A 1 822  GLY 822  837  ?   ?   ?   A . n 
A 1 823  THR 823  838  ?   ?   ?   A . n 
A 1 824  PHE 824  839  ?   ?   ?   A . n 
A 1 825  CYS 825  840  ?   ?   ?   A . n 
A 1 826  ASP 826  841  ?   ?   ?   A . n 
A 1 827  ASN 827  842  ?   ?   ?   A . n 
A 1 828  ILE 828  843  ?   ?   ?   A . n 
A 1 829  ASN 829  844  ?   ?   ?   A . n 
A 1 830  SER 830  845  ?   ?   ?   A . n 
A 1 831  ILE 831  846  ?   ?   ?   A . n 
A 1 832  LEU 832  847  ?   ?   ?   A . n 
A 1 833  ASP 833  848  ?   ?   ?   A . n 
A 1 834  GLU 834  849  ?   ?   ?   A . n 
A 1 835  VAL 835  850  ?   ?   ?   A . n 
A 1 836  ASN 836  851  ?   ?   ?   A . n 
A 1 837  GLY 837  852  ?   ?   ?   A . n 
A 1 838  LEU 838  853  ?   ?   ?   A . n 
A 1 839  LEU 839  854  ?   ?   ?   A . n 
A 1 840  ASP 840  855  ?   ?   ?   A . n 
A 1 841  THR 841  856  ?   ?   ?   A . n 
A 1 842  THR 842  857  ?   ?   ?   A . n 
A 1 843  GLN 843  858  ?   ?   ?   A . n 
A 1 844  LEU 844  859  ?   ?   ?   A . n 
A 1 845  HIS 845  860  ?   ?   ?   A . n 
A 1 846  VAL 846  861  ?   ?   ?   A . n 
A 1 847  ALA 847  862  ?   ?   ?   A . n 
A 1 848  ASP 848  863  ?   ?   ?   A . n 
A 1 849  THR 849  864  ?   ?   ?   A . n 
A 1 850  LEU 850  865  ?   ?   ?   A . n 
A 1 851  MET 851  866  ?   ?   ?   A . n 
A 1 852  GLN 852  867  ?   ?   ?   A . n 
A 1 853  GLY 853  868  ?   ?   ?   A . n 
A 1 854  VAL 854  869  ?   ?   ?   A . n 
A 1 855  THR 855  870  ?   ?   ?   A . n 
A 1 856  LEU 856  871  ?   ?   ?   A . n 
A 1 857  SER 857  872  ?   ?   ?   A . n 
A 1 858  SER 858  873  ?   ?   ?   A . n 
A 1 859  ASN 859  874  ?   ?   ?   A . n 
A 1 860  LEU 860  875  ?   ?   ?   A . n 
A 1 861  ASN 861  876  ?   ?   ?   A . n 
A 1 862  THR 862  877  ?   ?   ?   A . n 
A 1 863  ASN 863  878  ?   ?   ?   A . n 
A 1 864  LEU 864  879  ?   ?   ?   A . n 
A 1 865  HIS 865  880  ?   ?   ?   A . n 
A 1 866  PHE 866  881  ?   ?   ?   A . n 
A 1 867  ASP 867  882  ?   ?   ?   A . n 
A 1 868  VAL 868  883  ?   ?   ?   A . n 
A 1 869  ASP 869  884  ?   ?   ?   A . n 
A 1 870  ASN 870  885  ?   ?   ?   A . n 
A 1 871  ILE 871  886  ?   ?   ?   A . n 
A 1 872  ASN 872  887  ?   ?   ?   A . n 
A 1 873  PHE 873  888  ?   ?   ?   A . n 
A 1 874  LYS 874  889  ?   ?   ?   A . n 
A 1 875  SER 875  890  ?   ?   ?   A . n 
A 1 876  LEU 876  891  ?   ?   ?   A . n 
A 1 877  VAL 877  892  ?   ?   ?   A . n 
A 1 878  GLY 878  893  ?   ?   ?   A . n 
A 1 879  CYS 879  894  ?   ?   ?   A . n 
A 1 880  LEU 880  895  ?   ?   ?   A . n 
A 1 881  GLY 881  896  ?   ?   ?   A . n 
A 1 882  PRO 882  897  ?   ?   ?   A . n 
A 1 883  HIS 883  898  ?   ?   ?   A . n 
A 1 884  CYS 884  899  ?   ?   ?   A . n 
A 1 885  GLY 885  900  ?   ?   ?   A . n 
A 1 886  SER 886  901  ?   ?   ?   A . n 
A 1 887  SER 887  902  ?   ?   ?   A . n 
A 1 888  SER 888  903  ?   ?   ?   A . n 
A 1 889  ARG 889  904  ?   ?   ?   A . n 
A 1 890  SER 890  905  ?   ?   ?   A . n 
A 1 891  PHE 891  906  ?   ?   ?   A . n 
A 1 892  PHE 892  907  ?   ?   ?   A . n 
A 1 893  GLU 893  908  ?   ?   ?   A . n 
A 1 894  ASP 894  909  ?   ?   ?   A . n 
A 1 895  LEU 895  910  ?   ?   ?   A . n 
A 1 896  LEU 896  911  ?   ?   ?   A . n 
A 1 897  PHE 897  912  ?   ?   ?   A . n 
A 1 898  ASP 898  913  ?   ?   ?   A . n 
A 1 899  LYS 899  914  ?   ?   ?   A . n 
A 1 900  VAL 900  915  ?   ?   ?   A . n 
A 1 901  LYS 901  916  ?   ?   ?   A . n 
A 1 902  LEU 902  917  ?   ?   ?   A . n 
A 1 903  SER 903  918  ?   ?   ?   A . n 
A 1 904  ASP 904  919  ?   ?   ?   A . n 
A 1 905  VAL 905  920  ?   ?   ?   A . n 
A 1 906  GLY 906  921  ?   ?   ?   A . n 
A 1 907  PHE 907  922  ?   ?   ?   A . n 
A 1 908  VAL 908  923  ?   ?   ?   A . n 
A 1 909  GLU 909  924  ?   ?   ?   A . n 
A 1 910  ALA 910  925  ?   ?   ?   A . n 
A 1 911  TYR 911  926  ?   ?   ?   A . n 
A 1 912  ASN 912  927  ?   ?   ?   A . n 
A 1 913  ASN 913  928  ?   ?   ?   A . n 
A 1 914  CYS 914  929  ?   ?   ?   A . n 
A 1 915  THR 915  930  ?   ?   ?   A . n 
A 1 916  GLY 916  931  ?   ?   ?   A . n 
A 1 917  GLY 917  932  ?   ?   ?   A . n 
A 1 918  SER 918  933  ?   ?   ?   A . n 
A 1 919  GLU 919  934  ?   ?   ?   A . n 
A 1 920  ILE 920  935  ?   ?   ?   A . n 
A 1 921  ARG 921  936  ?   ?   ?   A . n 
A 1 922  ASP 922  937  ?   ?   ?   A . n 
A 1 923  LEU 923  938  ?   ?   ?   A . n 
A 1 924  LEU 924  939  ?   ?   ?   A . n 
A 1 925  CYS 925  940  ?   ?   ?   A . n 
A 1 926  VAL 926  941  ?   ?   ?   A . n 
A 1 927  GLN 927  942  ?   ?   ?   A . n 
A 1 928  SER 928  943  ?   ?   ?   A . n 
A 1 929  PHE 929  944  ?   ?   ?   A . n 
A 1 930  ASN 930  945  ?   ?   ?   A . n 
A 1 931  GLY 931  946  ?   ?   ?   A . n 
A 1 932  ILE 932  947  ?   ?   ?   A . n 
A 1 933  LYS 933  948  ?   ?   ?   A . n 
A 1 934  VAL 934  949  ?   ?   ?   A . n 
A 1 935  LEU 935  950  ?   ?   ?   A . n 
A 1 936  PRO 936  951  ?   ?   ?   A . n 
A 1 937  PRO 937  952  ?   ?   ?   A . n 
A 1 938  ILE 938  953  ?   ?   ?   A . n 
A 1 939  LEU 939  954  ?   ?   ?   A . n 
A 1 940  SER 940  955  ?   ?   ?   A . n 
A 1 941  GLU 941  956  ?   ?   ?   A . n 
A 1 942  SER 942  957  ?   ?   ?   A . n 
A 1 943  GLN 943  958  ?   ?   ?   A . n 
A 1 944  ILE 944  959  ?   ?   ?   A . n 
A 1 945  SER 945  960  ?   ?   ?   A . n 
A 1 946  GLY 946  961  ?   ?   ?   A . n 
A 1 947  TYR 947  962  ?   ?   ?   A . n 
A 1 948  THR 948  963  ?   ?   ?   A . n 
A 1 949  THR 949  964  ?   ?   ?   A . n 
A 1 950  ALA 950  965  ?   ?   ?   A . n 
A 1 951  ALA 951  966  ?   ?   ?   A . n 
A 1 952  THR 952  967  ?   ?   ?   A . n 
A 1 953  VAL 953  968  ?   ?   ?   A . n 
A 1 954  ALA 954  969  ?   ?   ?   A . n 
A 1 955  ALA 955  970  ?   ?   ?   A . n 
A 1 956  MET 956  971  ?   ?   ?   A . n 
A 1 957  PHE 957  972  ?   ?   ?   A . n 
A 1 958  PRO 958  973  ?   ?   ?   A . n 
A 1 959  PRO 959  974  ?   ?   ?   A . n 
A 1 960  TRP 960  975  ?   ?   ?   A . n 
A 1 961  SER 961  976  ?   ?   ?   A . n 
A 1 962  ALA 962  977  ?   ?   ?   A . n 
A 1 963  ALA 963  978  ?   ?   ?   A . n 
A 1 964  ALA 964  979  ?   ?   ?   A . n 
A 1 965  GLY 965  980  ?   ?   ?   A . n 
A 1 966  ILE 966  981  ?   ?   ?   A . n 
A 1 967  PRO 967  982  ?   ?   ?   A . n 
A 1 968  PHE 968  983  ?   ?   ?   A . n 
A 1 969  SER 969  984  ?   ?   ?   A . n 
A 1 970  LEU 970  985  ?   ?   ?   A . n 
A 1 971  ASN 971  986  ?   ?   ?   A . n 
A 1 972  VAL 972  987  ?   ?   ?   A . n 
A 1 973  GLN 973  988  ?   ?   ?   A . n 
A 1 974  TYR 974  989  ?   ?   ?   A . n 
A 1 975  ARG 975  990  ?   ?   ?   A . n 
A 1 976  ILE 976  991  ?   ?   ?   A . n 
A 1 977  ASN 977  992  ?   ?   ?   A . n 
A 1 978  GLY 978  993  ?   ?   ?   A . n 
A 1 979  LEU 979  994  ?   ?   ?   A . n 
A 1 980  GLY 980  995  ?   ?   ?   A . n 
A 1 981  VAL 981  996  ?   ?   ?   A . n 
A 1 982  THR 982  997  ?   ?   ?   A . n 
A 1 983  MET 983  998  ?   ?   ?   A . n 
A 1 984  ASP 984  999  ?   ?   ?   A . n 
A 1 985  VAL 985  1000 ?   ?   ?   A . n 
A 1 986  LEU 986  1001 ?   ?   ?   A . n 
A 1 987  ASN 987  1002 ?   ?   ?   A . n 
A 1 988  LYS 988  1003 ?   ?   ?   A . n 
A 1 989  ASN 989  1004 ?   ?   ?   A . n 
A 1 990  GLN 990  1005 ?   ?   ?   A . n 
A 1 991  LYS 991  1006 ?   ?   ?   A . n 
A 1 992  LEU 992  1007 ?   ?   ?   A . n 
A 1 993  ILE 993  1008 ?   ?   ?   A . n 
A 1 994  ALA 994  1009 ?   ?   ?   A . n 
A 1 995  THR 995  1010 ?   ?   ?   A . n 
A 1 996  ALA 996  1011 ?   ?   ?   A . n 
A 1 997  PHE 997  1012 ?   ?   ?   A . n 
A 1 998  ASN 998  1013 ?   ?   ?   A . n 
A 1 999  ASN 999  1014 ?   ?   ?   A . n 
A 1 1000 ALA 1000 1015 ?   ?   ?   A . n 
A 1 1001 LEU 1001 1016 ?   ?   ?   A . n 
A 1 1002 LEU 1002 1017 ?   ?   ?   A . n 
A 1 1003 SER 1003 1018 ?   ?   ?   A . n 
A 1 1004 ILE 1004 1019 ?   ?   ?   A . n 
A 1 1005 GLN 1005 1020 ?   ?   ?   A . n 
A 1 1006 ASN 1006 1021 ?   ?   ?   A . n 
A 1 1007 GLY 1007 1022 ?   ?   ?   A . n 
A 1 1008 PHE 1008 1023 ?   ?   ?   A . n 
A 1 1009 SER 1009 1024 ?   ?   ?   A . n 
A 1 1010 ALA 1010 1025 ?   ?   ?   A . n 
A 1 1011 PRO 1011 1026 ?   ?   ?   A . n 
A 1 1012 ASN 1012 1027 ?   ?   ?   A . n 
A 1 1013 SER 1013 1028 ?   ?   ?   A . n 
A 1 1014 ALA 1014 1029 ?   ?   ?   A . n 
A 1 1015 LEU 1015 1030 ?   ?   ?   A . n 
A 1 1016 ALA 1016 1031 ?   ?   ?   A . n 
A 1 1017 LYS 1017 1032 ?   ?   ?   A . n 
A 1 1018 ILE 1018 1033 ?   ?   ?   A . n 
A 1 1019 GLN 1019 1034 ?   ?   ?   A . n 
A 1 1020 SER 1020 1035 ?   ?   ?   A . n 
A 1 1021 VAL 1021 1036 ?   ?   ?   A . n 
A 1 1022 VAL 1022 1037 ?   ?   ?   A . n 
A 1 1023 ASN 1023 1038 ?   ?   ?   A . n 
A 1 1024 SER 1024 1039 ?   ?   ?   A . n 
A 1 1025 ASN 1025 1040 ?   ?   ?   A . n 
A 1 1026 ALA 1026 1041 ?   ?   ?   A . n 
A 1 1027 GLN 1027 1042 ?   ?   ?   A . n 
A 1 1028 ALA 1028 1043 ?   ?   ?   A . n 
A 1 1029 LEU 1029 1044 ?   ?   ?   A . n 
A 1 1030 ASN 1030 1045 ?   ?   ?   A . n 
A 1 1031 SER 1031 1046 ?   ?   ?   A . n 
A 1 1032 LEU 1032 1047 ?   ?   ?   A . n 
A 1 1033 LEU 1033 1048 ?   ?   ?   A . n 
A 1 1034 GLN 1034 1049 ?   ?   ?   A . n 
A 1 1035 GLN 1035 1050 ?   ?   ?   A . n 
A 1 1036 LEU 1036 1051 ?   ?   ?   A . n 
A 1 1037 PHE 1037 1052 ?   ?   ?   A . n 
A 1 1038 ASN 1038 1053 ?   ?   ?   A . n 
A 1 1039 LYS 1039 1054 ?   ?   ?   A . n 
A 1 1040 PHE 1040 1055 ?   ?   ?   A . n 
A 1 1041 GLY 1041 1056 ?   ?   ?   A . n 
A 1 1042 ALA 1042 1057 ?   ?   ?   A . n 
A 1 1043 ILE 1043 1058 ?   ?   ?   A . n 
A 1 1044 SER 1044 1059 ?   ?   ?   A . n 
A 1 1045 SER 1045 1060 ?   ?   ?   A . n 
A 1 1046 SER 1046 1061 ?   ?   ?   A . n 
A 1 1047 LEU 1047 1062 ?   ?   ?   A . n 
A 1 1048 GLN 1048 1063 ?   ?   ?   A . n 
A 1 1049 GLU 1049 1064 ?   ?   ?   A . n 
A 1 1050 ILE 1050 1065 ?   ?   ?   A . n 
A 1 1051 LEU 1051 1066 ?   ?   ?   A . n 
A 1 1052 SER 1052 1067 ?   ?   ?   A . n 
A 1 1053 ARG 1053 1068 ?   ?   ?   A . n 
A 1 1054 LEU 1054 1069 ?   ?   ?   A . n 
A 1 1055 ASP 1055 1070 ?   ?   ?   A . n 
A 1 1056 PRO 1056 1071 ?   ?   ?   A . n 
A 1 1057 PRO 1057 1072 ?   ?   ?   A . n 
A 1 1058 GLU 1058 1073 ?   ?   ?   A . n 
A 1 1059 ALA 1059 1074 ?   ?   ?   A . n 
A 1 1060 GLN 1060 1075 ?   ?   ?   A . n 
A 1 1061 VAL 1061 1076 ?   ?   ?   A . n 
A 1 1062 GLN 1062 1077 ?   ?   ?   A . n 
A 1 1063 ILE 1063 1078 ?   ?   ?   A . n 
A 1 1064 ASP 1064 1079 ?   ?   ?   A . n 
A 1 1065 ARG 1065 1080 ?   ?   ?   A . n 
A 1 1066 LEU 1066 1081 ?   ?   ?   A . n 
A 1 1067 ILE 1067 1082 ?   ?   ?   A . n 
A 1 1068 ASN 1068 1083 ?   ?   ?   A . n 
A 1 1069 GLY 1069 1084 ?   ?   ?   A . n 
A 1 1070 ARG 1070 1085 ?   ?   ?   A . n 
A 1 1071 LEU 1071 1086 ?   ?   ?   A . n 
A 1 1072 THR 1072 1087 ?   ?   ?   A . n 
A 1 1073 ALA 1073 1088 ?   ?   ?   A . n 
A 1 1074 LEU 1074 1089 ?   ?   ?   A . n 
A 1 1075 ASN 1075 1090 ?   ?   ?   A . n 
A 1 1076 ALA 1076 1091 ?   ?   ?   A . n 
A 1 1077 TYR 1077 1092 ?   ?   ?   A . n 
A 1 1078 VAL 1078 1093 ?   ?   ?   A . n 
A 1 1079 SER 1079 1094 ?   ?   ?   A . n 
A 1 1080 GLN 1080 1095 ?   ?   ?   A . n 
A 1 1081 GLN 1081 1096 ?   ?   ?   A . n 
A 1 1082 LEU 1082 1097 ?   ?   ?   A . n 
A 1 1083 SER 1083 1098 ?   ?   ?   A . n 
A 1 1084 ASP 1084 1099 ?   ?   ?   A . n 
A 1 1085 ILE 1085 1100 ?   ?   ?   A . n 
A 1 1086 SER 1086 1101 ?   ?   ?   A . n 
A 1 1087 LEU 1087 1102 ?   ?   ?   A . n 
A 1 1088 VAL 1088 1103 ?   ?   ?   A . n 
A 1 1089 LYS 1089 1104 ?   ?   ?   A . n 
A 1 1090 PHE 1090 1105 ?   ?   ?   A . n 
A 1 1091 GLY 1091 1106 ?   ?   ?   A . n 
A 1 1092 ALA 1092 1107 ?   ?   ?   A . n 
A 1 1093 ALA 1093 1108 ?   ?   ?   A . n 
A 1 1094 LEU 1094 1109 ?   ?   ?   A . n 
A 1 1095 ALA 1095 1110 ?   ?   ?   A . n 
A 1 1096 MET 1096 1111 ?   ?   ?   A . n 
A 1 1097 GLU 1097 1112 ?   ?   ?   A . n 
A 1 1098 LYS 1098 1113 ?   ?   ?   A . n 
A 1 1099 VAL 1099 1114 ?   ?   ?   A . n 
A 1 1100 ASN 1100 1115 ?   ?   ?   A . n 
A 1 1101 GLU 1101 1116 ?   ?   ?   A . n 
A 1 1102 CYS 1102 1117 ?   ?   ?   A . n 
A 1 1103 VAL 1103 1118 ?   ?   ?   A . n 
A 1 1104 LYS 1104 1119 ?   ?   ?   A . n 
A 1 1105 SER 1105 1120 ?   ?   ?   A . n 
A 1 1106 GLN 1106 1121 ?   ?   ?   A . n 
A 1 1107 SER 1107 1122 ?   ?   ?   A . n 
A 1 1108 PRO 1108 1123 ?   ?   ?   A . n 
A 1 1109 ARG 1109 1124 ?   ?   ?   A . n 
A 1 1110 ILE 1110 1125 ?   ?   ?   A . n 
A 1 1111 ASN 1111 1126 ?   ?   ?   A . n 
A 1 1112 PHE 1112 1127 ?   ?   ?   A . n 
A 1 1113 CYS 1113 1128 ?   ?   ?   A . n 
A 1 1114 GLY 1114 1129 ?   ?   ?   A . n 
A 1 1115 ASN 1115 1130 ?   ?   ?   A . n 
A 1 1116 GLY 1116 1131 ?   ?   ?   A . n 
A 1 1117 ASN 1117 1132 ?   ?   ?   A . n 
A 1 1118 HIS 1118 1133 ?   ?   ?   A . n 
A 1 1119 ILE 1119 1134 ?   ?   ?   A . n 
A 1 1120 LEU 1120 1135 ?   ?   ?   A . n 
A 1 1121 SER 1121 1136 ?   ?   ?   A . n 
A 1 1122 LEU 1122 1137 ?   ?   ?   A . n 
A 1 1123 VAL 1123 1138 ?   ?   ?   A . n 
A 1 1124 GLN 1124 1139 ?   ?   ?   A . n 
A 1 1125 ASN 1125 1140 ?   ?   ?   A . n 
A 1 1126 ALA 1126 1141 ?   ?   ?   A . n 
A 1 1127 PRO 1127 1142 ?   ?   ?   A . n 
A 1 1128 TYR 1128 1143 ?   ?   ?   A . n 
A 1 1129 GLY 1129 1144 ?   ?   ?   A . n 
A 1 1130 LEU 1130 1145 ?   ?   ?   A . n 
A 1 1131 LEU 1131 1146 ?   ?   ?   A . n 
A 1 1132 PHE 1132 1147 ?   ?   ?   A . n 
A 1 1133 MET 1133 1148 ?   ?   ?   A . n 
A 1 1134 HIS 1134 1149 ?   ?   ?   A . n 
A 1 1135 PHE 1135 1150 ?   ?   ?   A . n 
A 1 1136 SER 1136 1151 ?   ?   ?   A . n 
A 1 1137 TYR 1137 1152 ?   ?   ?   A . n 
A 1 1138 LYS 1138 1153 ?   ?   ?   A . n 
A 1 1139 PRO 1139 1154 ?   ?   ?   A . n 
A 1 1140 ILE 1140 1155 ?   ?   ?   A . n 
A 1 1141 SER 1141 1156 ?   ?   ?   A . n 
A 1 1142 PHE 1142 1157 ?   ?   ?   A . n 
A 1 1143 LYS 1143 1158 ?   ?   ?   A . n 
A 1 1144 THR 1144 1159 ?   ?   ?   A . n 
A 1 1145 VAL 1145 1160 ?   ?   ?   A . n 
A 1 1146 LEU 1146 1161 ?   ?   ?   A . n 
A 1 1147 VAL 1147 1162 ?   ?   ?   A . n 
A 1 1148 SER 1148 1163 ?   ?   ?   A . n 
A 1 1149 PRO 1149 1164 ?   ?   ?   A . n 
A 1 1150 GLY 1150 1165 ?   ?   ?   A . n 
A 1 1151 LEU 1151 1166 ?   ?   ?   A . n 
A 1 1152 CYS 1152 1167 ?   ?   ?   A . n 
A 1 1153 ILE 1153 1168 ?   ?   ?   A . n 
A 1 1154 SER 1154 1169 ?   ?   ?   A . n 
A 1 1155 GLY 1155 1170 ?   ?   ?   A . n 
A 1 1156 ASP 1156 1171 ?   ?   ?   A . n 
A 1 1157 VAL 1157 1172 ?   ?   ?   A . n 
A 1 1158 GLY 1158 1173 ?   ?   ?   A . n 
A 1 1159 ILE 1159 1174 ?   ?   ?   A . n 
A 1 1160 ALA 1160 1175 ?   ?   ?   A . n 
A 1 1161 PRO 1161 1176 ?   ?   ?   A . n 
A 1 1162 LYS 1162 1177 ?   ?   ?   A . n 
A 1 1163 GLN 1163 1178 ?   ?   ?   A . n 
A 1 1164 GLY 1164 1179 ?   ?   ?   A . n 
A 1 1165 TYR 1165 1180 ?   ?   ?   A . n 
A 1 1166 PHE 1166 1181 ?   ?   ?   A . n 
A 1 1167 ILE 1167 1182 ?   ?   ?   A . n 
A 1 1168 LYS 1168 1183 ?   ?   ?   A . n 
A 1 1169 HIS 1169 1184 ?   ?   ?   A . n 
A 1 1170 ASN 1170 1185 ?   ?   ?   A . n 
A 1 1171 ASP 1171 1186 ?   ?   ?   A . n 
A 1 1172 HIS 1172 1187 ?   ?   ?   A . n 
A 1 1173 TRP 1173 1188 ?   ?   ?   A . n 
A 1 1174 MET 1174 1189 ?   ?   ?   A . n 
A 1 1175 PHE 1175 1190 ?   ?   ?   A . n 
A 1 1176 THR 1176 1191 ?   ?   ?   A . n 
A 1 1177 GLY 1177 1192 ?   ?   ?   A . n 
A 1 1178 SER 1178 1193 ?   ?   ?   A . n 
A 1 1179 SER 1179 1194 ?   ?   ?   A . n 
A 1 1180 TYR 1180 1195 ?   ?   ?   A . n 
A 1 1181 TYR 1181 1196 ?   ?   ?   A . n 
A 1 1182 TYR 1182 1197 ?   ?   ?   A . n 
A 1 1183 PRO 1183 1198 ?   ?   ?   A . n 
A 1 1184 GLU 1184 1199 ?   ?   ?   A . n 
A 1 1185 PRO 1185 1200 ?   ?   ?   A . n 
A 1 1186 ILE 1186 1201 ?   ?   ?   A . n 
A 1 1187 SER 1187 1202 ?   ?   ?   A . n 
A 1 1188 ASP 1188 1203 ?   ?   ?   A . n 
A 1 1189 LYS 1189 1204 ?   ?   ?   A . n 
A 1 1190 ASN 1190 1205 ?   ?   ?   A . n 
A 1 1191 VAL 1191 1206 ?   ?   ?   A . n 
A 1 1192 VAL 1192 1207 ?   ?   ?   A . n 
A 1 1193 PHE 1193 1208 ?   ?   ?   A . n 
A 1 1194 MET 1194 1209 ?   ?   ?   A . n 
A 1 1195 ASN 1195 1210 ?   ?   ?   A . n 
A 1 1196 THR 1196 1211 ?   ?   ?   A . n 
A 1 1197 CYS 1197 1212 ?   ?   ?   A . n 
A 1 1198 SER 1198 1213 ?   ?   ?   A . n 
A 1 1199 VAL 1199 1214 ?   ?   ?   A . n 
A 1 1200 ASN 1200 1215 ?   ?   ?   A . n 
A 1 1201 PHE 1201 1216 ?   ?   ?   A . n 
A 1 1202 THR 1202 1217 ?   ?   ?   A . n 
A 1 1203 LYS 1203 1218 ?   ?   ?   A . n 
A 1 1204 ALA 1204 1219 ?   ?   ?   A . n 
A 1 1205 PRO 1205 1220 ?   ?   ?   A . n 
A 1 1206 LEU 1206 1221 ?   ?   ?   A . n 
A 1 1207 VAL 1207 1222 ?   ?   ?   A . n 
A 1 1208 TYR 1208 1223 ?   ?   ?   A . n 
A 1 1209 LEU 1209 1224 ?   ?   ?   A . n 
A 1 1210 ASN 1210 1225 ?   ?   ?   A . n 
A 1 1211 HIS 1211 1226 ?   ?   ?   A . n 
A 1 1212 SER 1212 1227 ?   ?   ?   A . n 
A 1 1213 VAL 1213 1228 ?   ?   ?   A . n 
A 1 1214 PRO 1214 1229 ?   ?   ?   A . n 
A 1 1215 LYS 1215 1230 ?   ?   ?   A . n 
A 1 1216 LEU 1216 1231 ?   ?   ?   A . n 
A 1 1217 SER 1217 1232 ?   ?   ?   A . n 
A 1 1218 ASP 1218 1233 ?   ?   ?   A . n 
A 1 1219 PHE 1219 1234 ?   ?   ?   A . n 
A 1 1220 GLU 1220 1235 ?   ?   ?   A . n 
A 1 1221 SER 1221 1236 ?   ?   ?   A . n 
A 1 1222 GLU 1222 1237 ?   ?   ?   A . n 
A 1 1223 LEU 1223 1238 ?   ?   ?   A . n 
A 1 1224 SER 1224 1239 ?   ?   ?   A . n 
A 1 1225 HIS 1225 1240 ?   ?   ?   A . n 
A 1 1226 TRP 1226 1241 ?   ?   ?   A . n 
A 1 1227 PHE 1227 1242 ?   ?   ?   A . n 
A 1 1228 LYS 1228 1243 ?   ?   ?   A . n 
A 1 1229 ASN 1229 1244 ?   ?   ?   A . n 
A 1 1230 GLN 1230 1245 ?   ?   ?   A . n 
A 1 1231 THR 1231 1246 ?   ?   ?   A . n 
A 1 1232 SER 1232 1247 ?   ?   ?   A . n 
A 1 1233 ILE 1233 1248 ?   ?   ?   A . n 
A 1 1234 ALA 1234 1249 ?   ?   ?   A . n 
A 1 1235 PRO 1235 1250 ?   ?   ?   A . n 
A 1 1236 ASN 1236 1251 ?   ?   ?   A . n 
A 1 1237 LEU 1237 1252 ?   ?   ?   A . n 
A 1 1238 THR 1238 1253 ?   ?   ?   A . n 
A 1 1239 LEU 1239 1254 ?   ?   ?   A . n 
A 1 1240 ASN 1240 1255 ?   ?   ?   A . n 
A 1 1241 LEU 1241 1256 ?   ?   ?   A . n 
A 1 1242 HIS 1242 1257 ?   ?   ?   A . n 
A 1 1243 THR 1243 1258 ?   ?   ?   A . n 
A 1 1244 ILE 1244 1259 ?   ?   ?   A . n 
A 1 1245 ASN 1245 1260 ?   ?   ?   A . n 
A 1 1246 ALA 1246 1261 ?   ?   ?   A . n 
A 1 1247 THR 1247 1262 ?   ?   ?   A . n 
A 1 1248 PHE 1248 1263 ?   ?   ?   A . n 
A 1 1249 LEU 1249 1264 ?   ?   ?   A . n 
A 1 1250 ASP 1250 1265 ?   ?   ?   A . n 
A 1 1251 LEU 1251 1266 ?   ?   ?   A . n 
A 1 1252 TYR 1252 1267 ?   ?   ?   A . n 
A 1 1253 TYR 1253 1268 ?   ?   ?   A . n 
A 1 1254 GLU 1254 1269 ?   ?   ?   A . n 
A 1 1255 MET 1255 1270 ?   ?   ?   A . n 
A 1 1256 ASN 1256 1271 ?   ?   ?   A . n 
A 1 1257 LEU 1257 1272 ?   ?   ?   A . n 
A 1 1258 ILE 1258 1273 ?   ?   ?   A . n 
A 1 1259 GLN 1259 1274 ?   ?   ?   A . n 
A 1 1260 GLU 1260 1275 ?   ?   ?   A . n 
A 1 1261 SER 1261 1276 ?   ?   ?   A . n 
A 1 1262 ILE 1262 1277 ?   ?   ?   A . n 
A 1 1263 LYS 1263 1278 ?   ?   ?   A . n 
A 1 1264 SER 1264 1279 ?   ?   ?   A . n 
A 1 1265 LEU 1265 1280 ?   ?   ?   A . n 
A 1 1266 ASN 1266 1281 ?   ?   ?   A . n 
A 1 1267 ASN 1267 1282 ?   ?   ?   A . n 
A 1 1268 SER 1268 1283 ?   ?   ?   A . n 
A 1 1269 TYR 1269 1284 ?   ?   ?   A . n 
A 1 1270 ILE 1270 1285 ?   ?   ?   A . n 
A 1 1271 ASN 1271 1286 ?   ?   ?   A . n 
A 1 1272 LEU 1272 1287 ?   ?   ?   A . n 
A 1 1273 LYS 1273 1288 ?   ?   ?   A . n 
A 1 1274 ASP 1274 1289 ?   ?   ?   A . n 
A 1 1275 ILE 1275 1290 ?   ?   ?   A . n 
A 1 1276 GLY 1276 1291 ?   ?   ?   A . n 
A 1 1277 THR 1277 1292 ?   ?   ?   A . n 
A 1 1278 TYR 1278 1293 ?   ?   ?   A . n 
A 1 1279 GLU 1279 1294 ?   ?   ?   A . n 
A 1 1280 MET 1280 1295 ?   ?   ?   A . n 
A 1 1281 TYR 1281 1296 ?   ?   ?   A . n 
A 1 1282 VAL 1282 1297 ?   ?   ?   A . n 
A 1 1283 LYS 1283 1298 ?   ?   ?   A . n 
A 1 1284 SER 1284 1299 ?   ?   ?   A . n 
A 1 1285 GLY 1285 1300 ?   ?   ?   A . n 
A 1 1286 GLY 1286 1301 ?   ?   ?   A . n 
A 1 1287 TYR 1287 1302 ?   ?   ?   A . n 
A 1 1288 ILE 1288 1303 ?   ?   ?   A . n 
A 1 1289 PRO 1289 1304 ?   ?   ?   A . n 
A 1 1290 GLU 1290 1305 ?   ?   ?   A . n 
A 1 1291 ALA 1291 1306 ?   ?   ?   A . n 
A 1 1292 PRO 1292 1307 ?   ?   ?   A . n 
A 1 1293 ARG 1293 1308 ?   ?   ?   A . n 
A 1 1294 ASP 1294 1309 ?   ?   ?   A . n 
A 1 1295 GLY 1295 1310 ?   ?   ?   A . n 
A 1 1296 GLN 1296 1311 ?   ?   ?   A . n 
A 1 1297 ALA 1297 1312 ?   ?   ?   A . n 
A 1 1298 TYR 1298 1313 ?   ?   ?   A . n 
A 1 1299 VAL 1299 1314 ?   ?   ?   A . n 
A 1 1300 ARG 1300 1315 ?   ?   ?   A . n 
A 1 1301 LYS 1301 1316 ?   ?   ?   A . n 
A 1 1302 ASP 1302 1317 ?   ?   ?   A . n 
A 1 1303 GLY 1303 1318 ?   ?   ?   A . n 
A 1 1304 GLU 1304 1319 ?   ?   ?   A . n 
A 1 1305 TRP 1305 1320 ?   ?   ?   A . n 
A 1 1306 VAL 1306 1321 ?   ?   ?   A . n 
A 1 1307 LEU 1307 1322 ?   ?   ?   A . n 
A 1 1308 LEU 1308 1323 ?   ?   ?   A . n 
A 1 1309 SER 1309 1324 ?   ?   ?   A . n 
A 1 1310 THR 1310 1325 ?   ?   ?   A . n 
A 1 1311 PHE 1311 1326 ?   ?   ?   A . n 
A 1 1312 LEU 1312 1327 ?   ?   ?   A . n 
A 1 1313 ASN 1313 1328 ?   ?   ?   A . n 
A 1 1314 SER 1314 1329 ?   ?   ?   A . n 
A 1 1315 GLY 1315 1330 ?   ?   ?   A . n 
A 1 1316 ARG 1316 1331 ?   ?   ?   A . n 
A 1 1317 ALA 1317 1332 ?   ?   ?   A . n 
A 1 1318 HIS 1318 1333 ?   ?   ?   A . n 
A 1 1319 HIS 1319 1334 ?   ?   ?   A . n 
A 1 1320 HIS 1320 1335 ?   ?   ?   A . n 
A 1 1321 HIS 1321 1336 ?   ?   ?   A . n 
A 1 1322 HIS 1322 1337 ?   ?   ?   A . n 
A 1 1323 HIS 1323 1338 ?   ?   ?   A . n 
A 1 1324 GLY 1324 1339 ?   ?   ?   A . n 
A 1 1325 ALA 1325 1340 ?   ?   ?   A . n 
A 1 1326 GLY 1326 1341 ?   ?   ?   A . n 
A 1 1327 GLY 1327 1342 ?   ?   ?   A . n 
A 1 1328 LEU 1328 1343 ?   ?   ?   A . n 
A 1 1329 ASN 1329 1344 ?   ?   ?   A . n 
A 1 1330 ASP 1330 1345 ?   ?   ?   A . n 
A 1 1331 ILE 1331 1346 ?   ?   ?   A . n 
A 1 1332 PHE 1332 1347 ?   ?   ?   A . n 
A 1 1333 GLU 1333 1348 ?   ?   ?   A . n 
A 1 1334 ALA 1334 1349 ?   ?   ?   A . n 
A 1 1335 GLN 1335 1350 ?   ?   ?   A . n 
A 1 1336 LYS 1336 1351 ?   ?   ?   A . n 
A 1 1337 ILE 1337 1352 ?   ?   ?   A . n 
A 1 1338 GLU 1338 1353 ?   ?   ?   A . n 
A 1 1339 TRP 1339 1354 ?   ?   ?   A . n 
A 1 1340 HIS 1340 1355 ?   ?   ?   A . n 
A 1 1341 GLU 1341 1356 ?   ?   ?   A . n 
A 1 1342 ASP 1342 1357 ?   ?   ?   A . n 
A 1 1343 THR 1343 1358 ?   ?   ?   A . n 
A 1 1344 ALA 1344 1359 ?   ?   ?   A . n 
A 1 1345 ALA 1345 1360 ?   ?   ?   A . n 
A 1 1346 ALA 1346 1361 ?   ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
B 2 NAG 1 B NAG 1 A NAG 1227 n 
B 2 NAG 2 B NAG 2 A NAG 1228 n 
B 2 BMA 3 B BMA 3 A BMA 1229 n 
B 2 MAN 4 B MAN 4 A MAN 1230 n 
B 2 MAN 5 B MAN 5 A MAN 1231 n 
C 3 NAG 1 C NAG 1 A NAG 1233 n 
C 3 NAG 2 C NAG 2 A NAG 1234 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 NAG 1 1401 1224 NAG NAG A . 
E 4 NAG 1 1402 1226 NAG NAG A . 
F 4 NAG 1 1403 1232 NAG NAG A . 
G 4 NAG 1 1404 1235 NAG NAG A . 
H 4 NAG 1 1405 1236 NAG NAG A . 
I 4 NAG 1 1406 1237 NAG NAG A . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9N17 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9N17 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9N17 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9N17 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.09 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_struct.entry_id                     9N17 
_struct.title                        'Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain (Deletion 33Pro34Arg)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9N17 
_struct_keywords.text            'HCoV-HKU1 spike glycoprotein ectodomain, proline stablized, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SPIKE_CVHN1 
_struct_ref.pdbx_db_accession          Q5MQD0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;VIGDFNCTNFAINDLNTTVPRISEYVVDVSYGLGTYYILDRVYLNTTILFTGYFPKSGANFRDLSLKGTTYLSTLWYQKP
FLSDFNNGIFSRVKNTKLYVNKTLYSEFSTIVIGSVFINNSYTIVVQPHNGVLEITACQYTMCEYPHTICKSKGSSRNES
WHFDKSEPLCLFKKNFTYNVSTDWLYFHFYQERGTFYAYYADSGMPTTFLFSLYLGTLLSHYYVLPLTCNAISSNTDNET
LQYWVTPLSKRQYLLKFDNRGVITNAVDCSSSFFSEIQCKTKSLLPNTGVYDLSGFTVKPVATVHRRIPDLPDCDIDKWL
NNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSIVLDKFAIPNSRRSDLQLGSSGFLQSSN
YKIDTTSSSCQLYYSLPAINVTINNYNPSSWNRRYGFNNFNLSSHSVVYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSA
SCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLVGVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDA
FLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDVCVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDS
NGNIIGFKDFVTNKTYNIFPCYAGRVSAAFHQNASSLALLYRNLKCSYVLNNISLTTQPYFDSYLGCVFNADNLTDYSVS
SCALRMGSGFCVDYNSPSSSSSRRKRRSISASYRFVTFEPFNVSFVNDSIESVGGLYEIKIPTNFTIVGQEEFIQTNSPK
VTIDCSLFVCSNYAACHDLLSEYGTFCDNINSILDEVNGLLDTTQLHVADTLMQGVTLSSNLNTNLHFDVDNINFKSLVG
CLGPHCGSSSRSFFEDLLFDKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSESQISGYTTAATVAAMFP
PWSAAAGIPFSLNVQYRINGLGVTMDVLNKNQKLIATAFNNALLSIQNGFSATNSALAKIQSVVNSNAQALNSLLQQLFN
KFGAISSSLQEILSRLDALEAQVQIDRLINGRLTALNAYVSQQLSDISLVKFGAALAMEKVNECVKSQSPRINFCGNGNH
ILSLVQNAPYGLLFMHFSYKPISFKTVLVSPGLCISGDVGIAPKQGYFIKHNDHWMFTGSSYYYPEPISDKNVVFMNTCS
VNFTKAPLVYLNHSVPKLSDFESELSHWFKNQTSIAPNLTLNLHTINATFLDLYYEMNLIQESIKSLNNSYINLKDIGTY
EMYVK
;
_struct_ref.pdbx_align_begin           14 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9N17 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1283 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q5MQD0 
_struct_ref_seq.db_align_beg                  14 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1298 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       14 
_struct_ref_seq.pdbx_auth_seq_align_end       1298 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9N17 ?   A ?    ? UNP Q5MQD0 PRO 33   deletion         ?    1  
1 9N17 ?   A ?    ? UNP Q5MQD0 ARG 34   deletion         ?    2  
1 9N17 PRO A 1011 ? UNP Q5MQD0 THR 1026 conflict         1026 3  
1 9N17 PRO A 1056 ? UNP Q5MQD0 ALA 1071 conflict         1071 4  
1 9N17 PRO A 1057 ? UNP Q5MQD0 LEU 1072 conflict         1072 5  
1 9N17 SER A 1284 ? UNP Q5MQD0 ?   ?    'expression tag' 1299 6  
1 9N17 GLY A 1285 ? UNP Q5MQD0 ?   ?    'expression tag' 1300 7  
1 9N17 GLY A 1286 ? UNP Q5MQD0 ?   ?    'expression tag' 1301 8  
1 9N17 TYR A 1287 ? UNP Q5MQD0 ?   ?    'expression tag' 1302 9  
1 9N17 ILE A 1288 ? UNP Q5MQD0 ?   ?    'expression tag' 1303 10 
1 9N17 PRO A 1289 ? UNP Q5MQD0 ?   ?    'expression tag' 1304 11 
1 9N17 GLU A 1290 ? UNP Q5MQD0 ?   ?    'expression tag' 1305 12 
1 9N17 ALA A 1291 ? UNP Q5MQD0 ?   ?    'expression tag' 1306 13 
1 9N17 PRO A 1292 ? UNP Q5MQD0 ?   ?    'expression tag' 1307 14 
1 9N17 ARG A 1293 ? UNP Q5MQD0 ?   ?    'expression tag' 1308 15 
1 9N17 ASP A 1294 ? UNP Q5MQD0 ?   ?    'expression tag' 1309 16 
1 9N17 GLY A 1295 ? UNP Q5MQD0 ?   ?    'expression tag' 1310 17 
1 9N17 GLN A 1296 ? UNP Q5MQD0 ?   ?    'expression tag' 1311 18 
1 9N17 ALA A 1297 ? UNP Q5MQD0 ?   ?    'expression tag' 1312 19 
1 9N17 TYR A 1298 ? UNP Q5MQD0 ?   ?    'expression tag' 1313 20 
1 9N17 VAL A 1299 ? UNP Q5MQD0 ?   ?    'expression tag' 1314 21 
1 9N17 ARG A 1300 ? UNP Q5MQD0 ?   ?    'expression tag' 1315 22 
1 9N17 LYS A 1301 ? UNP Q5MQD0 ?   ?    'expression tag' 1316 23 
1 9N17 ASP A 1302 ? UNP Q5MQD0 ?   ?    'expression tag' 1317 24 
1 9N17 GLY A 1303 ? UNP Q5MQD0 ?   ?    'expression tag' 1318 25 
1 9N17 GLU A 1304 ? UNP Q5MQD0 ?   ?    'expression tag' 1319 26 
1 9N17 TRP A 1305 ? UNP Q5MQD0 ?   ?    'expression tag' 1320 27 
1 9N17 VAL A 1306 ? UNP Q5MQD0 ?   ?    'expression tag' 1321 28 
1 9N17 LEU A 1307 ? UNP Q5MQD0 ?   ?    'expression tag' 1322 29 
1 9N17 LEU A 1308 ? UNP Q5MQD0 ?   ?    'expression tag' 1323 30 
1 9N17 SER A 1309 ? UNP Q5MQD0 ?   ?    'expression tag' 1324 31 
1 9N17 THR A 1310 ? UNP Q5MQD0 ?   ?    'expression tag' 1325 32 
1 9N17 PHE A 1311 ? UNP Q5MQD0 ?   ?    'expression tag' 1326 33 
1 9N17 LEU A 1312 ? UNP Q5MQD0 ?   ?    'expression tag' 1327 34 
1 9N17 ASN A 1313 ? UNP Q5MQD0 ?   ?    'expression tag' 1328 35 
1 9N17 SER A 1314 ? UNP Q5MQD0 ?   ?    'expression tag' 1329 36 
1 9N17 GLY A 1315 ? UNP Q5MQD0 ?   ?    'expression tag' 1330 37 
1 9N17 ARG A 1316 ? UNP Q5MQD0 ?   ?    'expression tag' 1331 38 
1 9N17 ALA A 1317 ? UNP Q5MQD0 ?   ?    'expression tag' 1332 39 
1 9N17 HIS A 1318 ? UNP Q5MQD0 ?   ?    'expression tag' 1333 40 
1 9N17 HIS A 1319 ? UNP Q5MQD0 ?   ?    'expression tag' 1334 41 
1 9N17 HIS A 1320 ? UNP Q5MQD0 ?   ?    'expression tag' 1335 42 
1 9N17 HIS A 1321 ? UNP Q5MQD0 ?   ?    'expression tag' 1336 43 
1 9N17 HIS A 1322 ? UNP Q5MQD0 ?   ?    'expression tag' 1337 44 
1 9N17 HIS A 1323 ? UNP Q5MQD0 ?   ?    'expression tag' 1338 45 
1 9N17 GLY A 1324 ? UNP Q5MQD0 ?   ?    'expression tag' 1339 46 
1 9N17 ALA A 1325 ? UNP Q5MQD0 ?   ?    'expression tag' 1340 47 
1 9N17 GLY A 1326 ? UNP Q5MQD0 ?   ?    'expression tag' 1341 48 
1 9N17 GLY A 1327 ? UNP Q5MQD0 ?   ?    'expression tag' 1342 49 
1 9N17 LEU A 1328 ? UNP Q5MQD0 ?   ?    'expression tag' 1343 50 
1 9N17 ASN A 1329 ? UNP Q5MQD0 ?   ?    'expression tag' 1344 51 
1 9N17 ASP A 1330 ? UNP Q5MQD0 ?   ?    'expression tag' 1345 52 
1 9N17 ILE A 1331 ? UNP Q5MQD0 ?   ?    'expression tag' 1346 53 
1 9N17 PHE A 1332 ? UNP Q5MQD0 ?   ?    'expression tag' 1347 54 
1 9N17 GLU A 1333 ? UNP Q5MQD0 ?   ?    'expression tag' 1348 55 
1 9N17 ALA A 1334 ? UNP Q5MQD0 ?   ?    'expression tag' 1349 56 
1 9N17 GLN A 1335 ? UNP Q5MQD0 ?   ?    'expression tag' 1350 57 
1 9N17 LYS A 1336 ? UNP Q5MQD0 ?   ?    'expression tag' 1351 58 
1 9N17 ILE A 1337 ? UNP Q5MQD0 ?   ?    'expression tag' 1352 59 
1 9N17 GLU A 1338 ? UNP Q5MQD0 ?   ?    'expression tag' 1353 60 
1 9N17 TRP A 1339 ? UNP Q5MQD0 ?   ?    'expression tag' 1354 61 
1 9N17 HIS A 1340 ? UNP Q5MQD0 ?   ?    'expression tag' 1355 62 
1 9N17 GLU A 1341 ? UNP Q5MQD0 ?   ?    'expression tag' 1356 63 
1 9N17 ASP A 1342 ? UNP Q5MQD0 ?   ?    'expression tag' 1357 64 
1 9N17 THR A 1343 ? UNP Q5MQD0 ?   ?    'expression tag' 1358 65 
1 9N17 ALA A 1344 ? UNP Q5MQD0 ?   ?    'expression tag' 1359 66 
1 9N17 ALA A 1345 ? UNP Q5MQD0 ?   ?    'expression tag' 1360 67 
1 9N17 ALA A 1346 ? UNP Q5MQD0 ?   ?    'expression tag' 1361 68 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
_struct_conf.conf_type_id            HELX_P 
_struct_conf.id                      HELX_P1 
_struct_conf.pdbx_PDB_helix_id       AA1 
_struct_conf.beg_label_comp_id       LEU 
_struct_conf.beg_label_asym_id       A 
_struct_conf.beg_label_seq_id        73 
_struct_conf.pdbx_beg_PDB_ins_code   ? 
_struct_conf.end_label_comp_id       GLN 
_struct_conf.end_label_asym_id       A 
_struct_conf.end_label_seq_id        76 
_struct_conf.pdbx_end_PDB_ins_code   ? 
_struct_conf.beg_auth_comp_id        LEU 
_struct_conf.beg_auth_asym_id        A 
_struct_conf.beg_auth_seq_id         88 
_struct_conf.end_auth_comp_id        GLN 
_struct_conf.end_auth_asym_id        A 
_struct_conf.end_auth_seq_id         91 
_struct_conf.pdbx_PDB_helix_class    5 
_struct_conf.details                 ? 
_struct_conf.pdbx_PDB_helix_length   4 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 7   SG  ? ? ? 1_555 A CYS 141 SG ? ? A CYS 20  A CYS 156  1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf2  disulf ?    ? A CYS 136 SG  ? ? ? 1_555 A CYS 168 SG ? ? A CYS 151 A CYS 183  1_555 ? ? ? ? ? ? ? 2.041 ? ?               
disulf3  disulf ?    ? A CYS 148 SG  ? ? ? 1_555 A CYS 227 SG ? ? A CYS 163 A CYS 242  1_555 ? ? ? ? ? ? ? 2.029 ? ?               
covale1  covale one  ? A ASN 6   ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 19  A NAG 1401 1_555 ? ? ? ? ? ? ? 1.447 ? N-Glycosylation 
covale2  covale one  ? A ASN 16  ND2 ? ? ? 1_555 I NAG .   C1 ? ? A ASN 29  A NAG 1406 1_555 ? ? ? ? ? ? ? 1.450 ? N-Glycosylation 
covale3  covale one  ? A ASN 43  ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 58  A NAG 1402 1_555 ? ? ? ? ? ? ? 1.449 ? N-Glycosylation 
covale4  covale one  ? A ASN 117 ND2 ? ? ? 1_555 B NAG .   C1 ? ? A ASN 132 B NAG 1    1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale5  covale one  ? A ASN 156 ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 171 A NAG 1403 1_555 ? ? ? ? ? ? ? 1.451 ? N-Glycosylation 
covale6  covale one  ? A ASN 173 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 188 C NAG 1    1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale7  covale one  ? A ASN 177 ND2 ? ? ? 1_555 G NAG .   C1 ? ? A ASN 192 A NAG 1404 1_555 ? ? ? ? ? ? ? 1.448 ? N-Glycosylation 
covale8  covale one  ? A ASN 236 ND2 ? ? ? 1_555 H NAG .   C1 ? ? A ASN 251 A NAG 1405 1_555 ? ? ? ? ? ? ? 1.448 ? N-Glycosylation 
covale9  covale both ? B NAG .   O4  ? ? ? 1_555 B NAG .   C1 ? ? B NAG 1   B NAG 2    1_555 ? ? ? ? ? ? ? 1.459 ? ?               
covale10 covale both ? B NAG .   O4  ? ? ? 1_555 B BMA .   C1 ? ? B NAG 2   B BMA 3    1_555 ? ? ? ? ? ? ? 1.460 ? ?               
covale11 covale both ? B BMA .   O3  ? ? ? 1_555 B MAN .   C1 ? ? B BMA 3   B MAN 4    1_555 ? ? ? ? ? ? ? 1.462 ? ?               
covale12 covale both ? B BMA .   O6  ? ? ? 1_555 B MAN .   C1 ? ? B BMA 3   B MAN 5    1_555 ? ? ? ? ? ? ? 1.463 ? ?               
covale13 covale both ? C NAG .   O4  ? ? ? 1_555 C NAG .   C1 ? ? C NAG 1   C NAG 2    1_555 ? ? ? ? ? ? ? 1.464 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG B .   ? ASN A 117 ? NAG B 1    ? 1_555 ASN A 132 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG C .   ? ASN A 173 ? NAG C 1    ? 1_555 ASN A 188 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG D .   ? ASN A 6   ? NAG A 1401 ? 1_555 ASN A 19  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG E .   ? ASN A 43  ? NAG A 1402 ? 1_555 ASN A 58  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG F .   ? ASN A 156 ? NAG A 1403 ? 1_555 ASN A 171 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG G .   ? ASN A 177 ? NAG A 1404 ? 1_555 ASN A 192 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG H .   ? ASN A 236 ? NAG A 1405 ? 1_555 ASN A 251 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG I .   ? ASN A 16  ? NAG A 1406 ? 1_555 ASN A 29  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  CYS A 7   ? CYS A 141 ? CYS A 20   ? 1_555 CYS A 156 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS A 136 ? CYS A 168 ? CYS A 151  ? 1_555 CYS A 183 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS A 148 ? CYS A 227 ? CYS A 163  ? 1_555 CYS A 242 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LYS 
_struct_mon_prot_cis.label_seq_id           77 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LYS 
_struct_mon_prot_cis.auth_seq_id            92 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    78 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     93 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       8.67 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 7 ? 
AA3 ? 3 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 12  ? ASN A 13  ? ILE A 25  ASN A 26  
AA1 2 LEU A 70  ? SER A 71  ? LEU A 85  SER A 86  
AA2 1 SER A 21  ? VAL A 24  ? SER A 36  VAL A 39  
AA2 2 ASN A 58  ? ASP A 61  ? ASN A 73  ASP A 76  
AA2 3 TYR A 241 ? PHE A 255 ? TYR A 256 PHE A 270 
AA2 4 GLY A 86  ? LYS A 92  ? GLY A 101 LYS A 107 
AA2 5 TRP A 182 ? GLU A 190 ? TRP A 197 GLU A 205 
AA2 6 THR A 193 ? ALA A 199 ? THR A 208 ALA A 214 
AA2 7 THR A 206 ? TYR A 212 ? THR A 221 TYR A 227 
AA3 1 THR A 44  ? PRO A 53  ? THR A 59  PRO A 68  
AA3 2 TYR A 241 ? PHE A 255 ? TYR A 256 PHE A 270 
AA3 3 ILE A 261 ? ASP A 266 ? ILE A 276 ASP A 281 
AA4 1 LYS A 65  ? GLY A 66  ? LYS A 80  GLY A 81  
AA4 2 LEU A 225 ? THR A 226 ? LEU A 240 THR A 241 
AA4 3 MET A 140 ? ILE A 147 ? MET A 155 ILE A 162 
AA4 4 SER A 158 ? HIS A 160 ? SER A 173 HIS A 175 
AA5 1 SER A 81  ? ASP A 82  ? SER A 96  ASP A 97  
AA5 2 HIS A 219 ? VAL A 222 ? HIS A 234 VAL A 237 
AA5 3 ILE A 109 ? GLY A 112 ? ILE A 124 GLY A 127 
AA5 4 THR A 121 ? HIS A 127 ? THR A 136 HIS A 142 
AA5 5 VAL A 130 ? CYS A 136 ? VAL A 145 CYS A 151 
AA5 6 CYS A 168 ? THR A 175 ? CYS A 183 THR A 190 
AA6 1 THR A 94  ? VAL A 98  ? THR A 109 VAL A 113 
AA6 2 THR A 101 ? GLU A 105 ? THR A 116 GLU A 120 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ASN A 13  ? N ASN A 26  O LEU A 70  ? O LEU A 85  
AA2 1 2 N TYR A 23  ? N TYR A 38  O PHE A 59  ? O PHE A 74  
AA2 2 3 N ARG A 60  ? N ARG A 75  O VAL A 243 ? O VAL A 258 
AA2 3 4 O TRP A 242 ? O TRP A 257 N ARG A 90  ? N ARG A 105 
AA2 4 5 N VAL A 91  ? N VAL A 106 O LEU A 183 ? O LEU A 198 
AA2 5 6 N TYR A 188 ? N TYR A 203 O TYR A 195 ? O TYR A 210 
AA2 6 7 N PHE A 194 ? N PHE A 209 O LEU A 211 ? O LEU A 226 
AA3 1 2 N PHE A 48  ? N PHE A 63  O TYR A 251 ? O TYR A 266 
AA3 2 3 N LYS A 254 ? N LYS A 269 O ASN A 263 ? O ASN A 278 
AA4 1 2 N GLY A 66  ? N GLY A 81  O LEU A 225 ? O LEU A 240 
AA4 2 3 O THR A 226 ? O THR A 241 N THR A 146 ? N THR A 161 
AA4 3 4 N CYS A 141 ? N CYS A 156 O TRP A 159 ? O TRP A 174 
AA5 1 2 N SER A 81  ? N SER A 96  O TYR A 220 ? O TYR A 235 
AA5 2 3 O HIS A 219 ? O HIS A 234 N GLY A 112 ? N GLY A 127 
AA5 3 4 N ILE A 111 ? N ILE A 126 O ILE A 122 ? O ILE A 137 
AA5 4 5 N HIS A 127 ? N HIS A 142 O VAL A 130 ? O VAL A 145 
AA5 5 6 N LEU A 131 ? N LEU A 146 O PHE A 174 ? O PHE A 189 
AA6 1 2 N LEU A 96  ? N LEU A 111 O TYR A 103 ? O TYR A 118 
# 
_pdbx_entry_details.entry_id                   9N17 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 NE A ARG 170 ? ? CZ A ARG 170 ? ? NH2 A ARG 170 ? ? 123.53 120.30 3.23 0.50 N 
2 1 NE A ARG 264 ? ? CZ A ARG 264 ? ? NH2 A ARG 264 ? ? 123.40 120.30 3.10 0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 17  ? ? -155.98 5.15    
2  1 THR A 30  ? ? -81.47  48.01   
3  1 LEU A 52  ? ? 49.36   -122.12 
4  1 ASN A 58  ? ? 37.09   54.53   
5  1 THR A 83  ? ? -140.64 -62.63  
6  1 ASN A 99  ? ? 48.47   -126.97 
7  1 LYS A 115 ? ? 57.82   18.87   
8  1 SER A 128 ? ? -129.34 -80.42  
9  1 ASN A 132 ? ? -64.81  13.12   
10 1 LYS A 186 ? ? -160.91 108.17  
11 1 ASP A 250 ? ? -155.65 -5.44   
12 1 ASN A 251 ? ? 55.39   15.57   
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    A 
_pdbx_validate_planes.auth_seq_id     206 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.080 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9N17 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_reconstruction.entry_id                    9N17 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.09 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               419307 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human coronavirus HKU1 spike glycoprotein' 
_em_entity_assembly.details              'Ectodomain generated by recombinant expression in HEK293 Freestyle cells' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9N17 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS GLACIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           92000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        C-flat-2/2 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.virus_type            VIRION 
_em_virus_entity.virus_isolate         ? 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.enveloped             ? 
_em_virus_entity.empty                 ? 
_em_virus_entity.details               ? 
# 
_em_vitrification.entry_id              9N17 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9N17 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1    1 Y 1 A SER 284  ? A SER 269  
2    1 Y 1 A SER 285  ? A SER 270  
3    1 Y 1 A PHE 286  ? A PHE 271  
4    1 Y 1 A PHE 287  ? A PHE 272  
5    1 Y 1 A SER 288  ? A SER 273  
6    1 Y 1 A GLU 289  ? A GLU 274  
7    1 Y 1 A ILE 290  ? A ILE 275  
8    1 Y 1 A GLN 291  ? A GLN 276  
9    1 Y 1 A CYS 292  ? A CYS 277  
10   1 Y 1 A LYS 293  ? A LYS 278  
11   1 Y 1 A THR 294  ? A THR 279  
12   1 Y 1 A LYS 295  ? A LYS 280  
13   1 Y 1 A SER 296  ? A SER 281  
14   1 Y 1 A LEU 297  ? A LEU 282  
15   1 Y 1 A LEU 298  ? A LEU 283  
16   1 Y 1 A PRO 299  ? A PRO 284  
17   1 Y 1 A ASN 300  ? A ASN 285  
18   1 Y 1 A THR 301  ? A THR 286  
19   1 Y 1 A GLY 302  ? A GLY 287  
20   1 Y 1 A VAL 303  ? A VAL 288  
21   1 Y 1 A TYR 304  ? A TYR 289  
22   1 Y 1 A ASP 305  ? A ASP 290  
23   1 Y 1 A LEU 306  ? A LEU 291  
24   1 Y 1 A SER 307  ? A SER 292  
25   1 Y 1 A GLY 308  ? A GLY 293  
26   1 Y 1 A PHE 309  ? A PHE 294  
27   1 Y 1 A THR 310  ? A THR 295  
28   1 Y 1 A VAL 311  ? A VAL 296  
29   1 Y 1 A LYS 312  ? A LYS 297  
30   1 Y 1 A PRO 313  ? A PRO 298  
31   1 Y 1 A VAL 314  ? A VAL 299  
32   1 Y 1 A ALA 315  ? A ALA 300  
33   1 Y 1 A THR 316  ? A THR 301  
34   1 Y 1 A VAL 317  ? A VAL 302  
35   1 Y 1 A HIS 318  ? A HIS 303  
36   1 Y 1 A ARG 319  ? A ARG 304  
37   1 Y 1 A ARG 320  ? A ARG 305  
38   1 Y 1 A ILE 321  ? A ILE 306  
39   1 Y 1 A PRO 322  ? A PRO 307  
40   1 Y 1 A ASP 323  ? A ASP 308  
41   1 Y 1 A LEU 324  ? A LEU 309  
42   1 Y 1 A PRO 325  ? A PRO 310  
43   1 Y 1 A ASP 326  ? A ASP 311  
44   1 Y 1 A CYS 327  ? A CYS 312  
45   1 Y 1 A ASP 328  ? A ASP 313  
46   1 Y 1 A ILE 329  ? A ILE 314  
47   1 Y 1 A ASP 330  ? A ASP 315  
48   1 Y 1 A LYS 331  ? A LYS 316  
49   1 Y 1 A TRP 332  ? A TRP 317  
50   1 Y 1 A LEU 333  ? A LEU 318  
51   1 Y 1 A ASN 334  ? A ASN 319  
52   1 Y 1 A ASN 335  ? A ASN 320  
53   1 Y 1 A PHE 336  ? A PHE 321  
54   1 Y 1 A ASN 337  ? A ASN 322  
55   1 Y 1 A VAL 338  ? A VAL 323  
56   1 Y 1 A PRO 339  ? A PRO 324  
57   1 Y 1 A SER 340  ? A SER 325  
58   1 Y 1 A PRO 341  ? A PRO 326  
59   1 Y 1 A LEU 342  ? A LEU 327  
60   1 Y 1 A ASN 343  ? A ASN 328  
61   1 Y 1 A TRP 344  ? A TRP 329  
62   1 Y 1 A GLU 345  ? A GLU 330  
63   1 Y 1 A ARG 346  ? A ARG 331  
64   1 Y 1 A LYS 347  ? A LYS 332  
65   1 Y 1 A ILE 348  ? A ILE 333  
66   1 Y 1 A PHE 349  ? A PHE 334  
67   1 Y 1 A SER 350  ? A SER 335  
68   1 Y 1 A ASN 351  ? A ASN 336  
69   1 Y 1 A CYS 352  ? A CYS 337  
70   1 Y 1 A ASN 353  ? A ASN 338  
71   1 Y 1 A PHE 354  ? A PHE 339  
72   1 Y 1 A ASN 355  ? A ASN 340  
73   1 Y 1 A LEU 356  ? A LEU 341  
74   1 Y 1 A SER 357  ? A SER 342  
75   1 Y 1 A THR 358  ? A THR 343  
76   1 Y 1 A LEU 359  ? A LEU 344  
77   1 Y 1 A LEU 360  ? A LEU 345  
78   1 Y 1 A ARG 361  ? A ARG 346  
79   1 Y 1 A LEU 362  ? A LEU 347  
80   1 Y 1 A VAL 363  ? A VAL 348  
81   1 Y 1 A HIS 364  ? A HIS 349  
82   1 Y 1 A THR 365  ? A THR 350  
83   1 Y 1 A ASP 366  ? A ASP 351  
84   1 Y 1 A SER 367  ? A SER 352  
85   1 Y 1 A PHE 368  ? A PHE 353  
86   1 Y 1 A SER 369  ? A SER 354  
87   1 Y 1 A CYS 370  ? A CYS 355  
88   1 Y 1 A ASN 371  ? A ASN 356  
89   1 Y 1 A ASN 372  ? A ASN 357  
90   1 Y 1 A PHE 373  ? A PHE 358  
91   1 Y 1 A ASP 374  ? A ASP 359  
92   1 Y 1 A GLU 375  ? A GLU 360  
93   1 Y 1 A SER 376  ? A SER 361  
94   1 Y 1 A LYS 377  ? A LYS 362  
95   1 Y 1 A ILE 378  ? A ILE 363  
96   1 Y 1 A TYR 379  ? A TYR 364  
97   1 Y 1 A GLY 380  ? A GLY 365  
98   1 Y 1 A SER 381  ? A SER 366  
99   1 Y 1 A CYS 382  ? A CYS 367  
100  1 Y 1 A PHE 383  ? A PHE 368  
101  1 Y 1 A LYS 384  ? A LYS 369  
102  1 Y 1 A SER 385  ? A SER 370  
103  1 Y 1 A ILE 386  ? A ILE 371  
104  1 Y 1 A VAL 387  ? A VAL 372  
105  1 Y 1 A LEU 388  ? A LEU 373  
106  1 Y 1 A ASP 389  ? A ASP 374  
107  1 Y 1 A LYS 390  ? A LYS 375  
108  1 Y 1 A PHE 391  ? A PHE 376  
109  1 Y 1 A ALA 392  ? A ALA 377  
110  1 Y 1 A ILE 393  ? A ILE 378  
111  1 Y 1 A PRO 394  ? A PRO 379  
112  1 Y 1 A ASN 395  ? A ASN 380  
113  1 Y 1 A SER 396  ? A SER 381  
114  1 Y 1 A ARG 397  ? A ARG 382  
115  1 Y 1 A ARG 398  ? A ARG 383  
116  1 Y 1 A SER 399  ? A SER 384  
117  1 Y 1 A ASP 400  ? A ASP 385  
118  1 Y 1 A LEU 401  ? A LEU 386  
119  1 Y 1 A GLN 402  ? A GLN 387  
120  1 Y 1 A LEU 403  ? A LEU 388  
121  1 Y 1 A GLY 404  ? A GLY 389  
122  1 Y 1 A SER 405  ? A SER 390  
123  1 Y 1 A SER 406  ? A SER 391  
124  1 Y 1 A GLY 407  ? A GLY 392  
125  1 Y 1 A PHE 408  ? A PHE 393  
126  1 Y 1 A LEU 409  ? A LEU 394  
127  1 Y 1 A GLN 410  ? A GLN 395  
128  1 Y 1 A SER 411  ? A SER 396  
129  1 Y 1 A SER 412  ? A SER 397  
130  1 Y 1 A ASN 413  ? A ASN 398  
131  1 Y 1 A TYR 414  ? A TYR 399  
132  1 Y 1 A LYS 415  ? A LYS 400  
133  1 Y 1 A ILE 416  ? A ILE 401  
134  1 Y 1 A ASP 417  ? A ASP 402  
135  1 Y 1 A THR 418  ? A THR 403  
136  1 Y 1 A THR 419  ? A THR 404  
137  1 Y 1 A SER 420  ? A SER 405  
138  1 Y 1 A SER 421  ? A SER 406  
139  1 Y 1 A SER 422  ? A SER 407  
140  1 Y 1 A CYS 423  ? A CYS 408  
141  1 Y 1 A GLN 424  ? A GLN 409  
142  1 Y 1 A LEU 425  ? A LEU 410  
143  1 Y 1 A TYR 426  ? A TYR 411  
144  1 Y 1 A TYR 427  ? A TYR 412  
145  1 Y 1 A SER 428  ? A SER 413  
146  1 Y 1 A LEU 429  ? A LEU 414  
147  1 Y 1 A PRO 430  ? A PRO 415  
148  1 Y 1 A ALA 431  ? A ALA 416  
149  1 Y 1 A ILE 432  ? A ILE 417  
150  1 Y 1 A ASN 433  ? A ASN 418  
151  1 Y 1 A VAL 434  ? A VAL 419  
152  1 Y 1 A THR 435  ? A THR 420  
153  1 Y 1 A ILE 436  ? A ILE 421  
154  1 Y 1 A ASN 437  ? A ASN 422  
155  1 Y 1 A ASN 438  ? A ASN 423  
156  1 Y 1 A TYR 439  ? A TYR 424  
157  1 Y 1 A ASN 440  ? A ASN 425  
158  1 Y 1 A PRO 441  ? A PRO 426  
159  1 Y 1 A SER 442  ? A SER 427  
160  1 Y 1 A SER 443  ? A SER 428  
161  1 Y 1 A TRP 444  ? A TRP 429  
162  1 Y 1 A ASN 445  ? A ASN 430  
163  1 Y 1 A ARG 446  ? A ARG 431  
164  1 Y 1 A ARG 447  ? A ARG 432  
165  1 Y 1 A TYR 448  ? A TYR 433  
166  1 Y 1 A GLY 449  ? A GLY 434  
167  1 Y 1 A PHE 450  ? A PHE 435  
168  1 Y 1 A ASN 451  ? A ASN 436  
169  1 Y 1 A ASN 452  ? A ASN 437  
170  1 Y 1 A PHE 453  ? A PHE 438  
171  1 Y 1 A ASN 454  ? A ASN 439  
172  1 Y 1 A LEU 455  ? A LEU 440  
173  1 Y 1 A SER 456  ? A SER 441  
174  1 Y 1 A SER 457  ? A SER 442  
175  1 Y 1 A HIS 458  ? A HIS 443  
176  1 Y 1 A SER 459  ? A SER 444  
177  1 Y 1 A VAL 460  ? A VAL 445  
178  1 Y 1 A VAL 461  ? A VAL 446  
179  1 Y 1 A TYR 462  ? A TYR 447  
180  1 Y 1 A SER 463  ? A SER 448  
181  1 Y 1 A ARG 464  ? A ARG 449  
182  1 Y 1 A TYR 465  ? A TYR 450  
183  1 Y 1 A CYS 466  ? A CYS 451  
184  1 Y 1 A PHE 467  ? A PHE 452  
185  1 Y 1 A SER 468  ? A SER 453  
186  1 Y 1 A VAL 469  ? A VAL 454  
187  1 Y 1 A ASN 470  ? A ASN 455  
188  1 Y 1 A ASN 471  ? A ASN 456  
189  1 Y 1 A THR 472  ? A THR 457  
190  1 Y 1 A PHE 473  ? A PHE 458  
191  1 Y 1 A CYS 474  ? A CYS 459  
192  1 Y 1 A PRO 475  ? A PRO 460  
193  1 Y 1 A CYS 476  ? A CYS 461  
194  1 Y 1 A ALA 477  ? A ALA 462  
195  1 Y 1 A LYS 478  ? A LYS 463  
196  1 Y 1 A PRO 479  ? A PRO 464  
197  1 Y 1 A SER 480  ? A SER 465  
198  1 Y 1 A PHE 481  ? A PHE 466  
199  1 Y 1 A ALA 482  ? A ALA 467  
200  1 Y 1 A SER 483  ? A SER 468  
201  1 Y 1 A SER 484  ? A SER 469  
202  1 Y 1 A CYS 485  ? A CYS 470  
203  1 Y 1 A LYS 486  ? A LYS 471  
204  1 Y 1 A SER 487  ? A SER 472  
205  1 Y 1 A HIS 488  ? A HIS 473  
206  1 Y 1 A LYS 489  ? A LYS 474  
207  1 Y 1 A PRO 490  ? A PRO 475  
208  1 Y 1 A PRO 491  ? A PRO 476  
209  1 Y 1 A SER 492  ? A SER 477  
210  1 Y 1 A ALA 493  ? A ALA 478  
211  1 Y 1 A SER 494  ? A SER 479  
212  1 Y 1 A CYS 495  ? A CYS 480  
213  1 Y 1 A PRO 496  ? A PRO 481  
214  1 Y 1 A ILE 497  ? A ILE 482  
215  1 Y 1 A GLY 498  ? A GLY 483  
216  1 Y 1 A THR 499  ? A THR 484  
217  1 Y 1 A ASN 500  ? A ASN 485  
218  1 Y 1 A TYR 501  ? A TYR 486  
219  1 Y 1 A ARG 502  ? A ARG 487  
220  1 Y 1 A SER 503  ? A SER 488  
221  1 Y 1 A CYS 504  ? A CYS 489  
222  1 Y 1 A GLU 505  ? A GLU 490  
223  1 Y 1 A SER 506  ? A SER 491  
224  1 Y 1 A THR 507  ? A THR 492  
225  1 Y 1 A THR 508  ? A THR 493  
226  1 Y 1 A VAL 509  ? A VAL 494  
227  1 Y 1 A LEU 510  ? A LEU 495  
228  1 Y 1 A ASP 511  ? A ASP 496  
229  1 Y 1 A HIS 512  ? A HIS 497  
230  1 Y 1 A THR 513  ? A THR 498  
231  1 Y 1 A ASP 514  ? A ASP 499  
232  1 Y 1 A TRP 515  ? A TRP 500  
233  1 Y 1 A CYS 516  ? A CYS 501  
234  1 Y 1 A ARG 517  ? A ARG 502  
235  1 Y 1 A CYS 518  ? A CYS 503  
236  1 Y 1 A SER 519  ? A SER 504  
237  1 Y 1 A CYS 520  ? A CYS 505  
238  1 Y 1 A LEU 521  ? A LEU 506  
239  1 Y 1 A PRO 522  ? A PRO 507  
240  1 Y 1 A ASP 523  ? A ASP 508  
241  1 Y 1 A PRO 524  ? A PRO 509  
242  1 Y 1 A ILE 525  ? A ILE 510  
243  1 Y 1 A THR 526  ? A THR 511  
244  1 Y 1 A ALA 527  ? A ALA 512  
245  1 Y 1 A TYR 528  ? A TYR 513  
246  1 Y 1 A ASP 529  ? A ASP 514  
247  1 Y 1 A PRO 530  ? A PRO 515  
248  1 Y 1 A ARG 531  ? A ARG 516  
249  1 Y 1 A SER 532  ? A SER 517  
250  1 Y 1 A CYS 533  ? A CYS 518  
251  1 Y 1 A SER 534  ? A SER 519  
252  1 Y 1 A GLN 535  ? A GLN 520  
253  1 Y 1 A LYS 536  ? A LYS 521  
254  1 Y 1 A LYS 537  ? A LYS 522  
255  1 Y 1 A SER 538  ? A SER 523  
256  1 Y 1 A LEU 539  ? A LEU 524  
257  1 Y 1 A VAL 540  ? A VAL 525  
258  1 Y 1 A GLY 541  ? A GLY 526  
259  1 Y 1 A VAL 542  ? A VAL 527  
260  1 Y 1 A GLY 543  ? A GLY 528  
261  1 Y 1 A GLU 544  ? A GLU 529  
262  1 Y 1 A HIS 545  ? A HIS 530  
263  1 Y 1 A CYS 546  ? A CYS 531  
264  1 Y 1 A ALA 547  ? A ALA 532  
265  1 Y 1 A GLY 548  ? A GLY 533  
266  1 Y 1 A PHE 549  ? A PHE 534  
267  1 Y 1 A GLY 550  ? A GLY 535  
268  1 Y 1 A VAL 551  ? A VAL 536  
269  1 Y 1 A ASP 552  ? A ASP 537  
270  1 Y 1 A GLU 553  ? A GLU 538  
271  1 Y 1 A GLU 554  ? A GLU 539  
272  1 Y 1 A LYS 555  ? A LYS 540  
273  1 Y 1 A CYS 556  ? A CYS 541  
274  1 Y 1 A GLY 557  ? A GLY 542  
275  1 Y 1 A VAL 558  ? A VAL 543  
276  1 Y 1 A LEU 559  ? A LEU 544  
277  1 Y 1 A ASP 560  ? A ASP 545  
278  1 Y 1 A GLY 561  ? A GLY 546  
279  1 Y 1 A SER 562  ? A SER 547  
280  1 Y 1 A TYR 563  ? A TYR 548  
281  1 Y 1 A ASN 564  ? A ASN 549  
282  1 Y 1 A VAL 565  ? A VAL 550  
283  1 Y 1 A SER 566  ? A SER 551  
284  1 Y 1 A CYS 567  ? A CYS 552  
285  1 Y 1 A LEU 568  ? A LEU 553  
286  1 Y 1 A CYS 569  ? A CYS 554  
287  1 Y 1 A SER 570  ? A SER 555  
288  1 Y 1 A THR 571  ? A THR 556  
289  1 Y 1 A ASP 572  ? A ASP 557  
290  1 Y 1 A ALA 573  ? A ALA 558  
291  1 Y 1 A PHE 574  ? A PHE 559  
292  1 Y 1 A LEU 575  ? A LEU 560  
293  1 Y 1 A GLY 576  ? A GLY 561  
294  1 Y 1 A TRP 577  ? A TRP 562  
295  1 Y 1 A SER 578  ? A SER 563  
296  1 Y 1 A TYR 579  ? A TYR 564  
297  1 Y 1 A ASP 580  ? A ASP 565  
298  1 Y 1 A THR 581  ? A THR 566  
299  1 Y 1 A CYS 582  ? A CYS 567  
300  1 Y 1 A VAL 583  ? A VAL 568  
301  1 Y 1 A SER 584  ? A SER 569  
302  1 Y 1 A ASN 585  ? A ASN 570  
303  1 Y 1 A ASN 586  ? A ASN 571  
304  1 Y 1 A ARG 587  ? A ARG 572  
305  1 Y 1 A CYS 588  ? A CYS 573  
306  1 Y 1 A ASN 589  ? A ASN 574  
307  1 Y 1 A ILE 590  ? A ILE 575  
308  1 Y 1 A PHE 591  ? A PHE 576  
309  1 Y 1 A SER 592  ? A SER 577  
310  1 Y 1 A ASN 593  ? A ASN 578  
311  1 Y 1 A PHE 594  ? A PHE 579  
312  1 Y 1 A ILE 595  ? A ILE 580  
313  1 Y 1 A LEU 596  ? A LEU 581  
314  1 Y 1 A ASN 597  ? A ASN 582  
315  1 Y 1 A GLY 598  ? A GLY 583  
316  1 Y 1 A ILE 599  ? A ILE 584  
317  1 Y 1 A ASN 600  ? A ASN 585  
318  1 Y 1 A SER 601  ? A SER 586  
319  1 Y 1 A GLY 602  ? A GLY 587  
320  1 Y 1 A THR 603  ? A THR 588  
321  1 Y 1 A THR 604  ? A THR 589  
322  1 Y 1 A CYS 605  ? A CYS 590  
323  1 Y 1 A SER 606  ? A SER 591  
324  1 Y 1 A ASN 607  ? A ASN 592  
325  1 Y 1 A ASP 608  ? A ASP 593  
326  1 Y 1 A LEU 609  ? A LEU 594  
327  1 Y 1 A LEU 610  ? A LEU 595  
328  1 Y 1 A GLN 611  ? A GLN 596  
329  1 Y 1 A PRO 612  ? A PRO 597  
330  1 Y 1 A ASN 613  ? A ASN 598  
331  1 Y 1 A THR 614  ? A THR 599  
332  1 Y 1 A GLU 615  ? A GLU 600  
333  1 Y 1 A VAL 616  ? A VAL 601  
334  1 Y 1 A PHE 617  ? A PHE 602  
335  1 Y 1 A THR 618  ? A THR 603  
336  1 Y 1 A ASP 619  ? A ASP 604  
337  1 Y 1 A VAL 620  ? A VAL 605  
338  1 Y 1 A CYS 621  ? A CYS 606  
339  1 Y 1 A VAL 622  ? A VAL 607  
340  1 Y 1 A ASP 623  ? A ASP 608  
341  1 Y 1 A TYR 624  ? A TYR 609  
342  1 Y 1 A ASP 625  ? A ASP 610  
343  1 Y 1 A LEU 626  ? A LEU 611  
344  1 Y 1 A TYR 627  ? A TYR 612  
345  1 Y 1 A GLY 628  ? A GLY 613  
346  1 Y 1 A ILE 629  ? A ILE 614  
347  1 Y 1 A THR 630  ? A THR 615  
348  1 Y 1 A GLY 631  ? A GLY 616  
349  1 Y 1 A GLN 632  ? A GLN 617  
350  1 Y 1 A GLY 633  ? A GLY 618  
351  1 Y 1 A ILE 634  ? A ILE 619  
352  1 Y 1 A PHE 635  ? A PHE 620  
353  1 Y 1 A LYS 636  ? A LYS 621  
354  1 Y 1 A GLU 637  ? A GLU 622  
355  1 Y 1 A VAL 638  ? A VAL 623  
356  1 Y 1 A SER 639  ? A SER 624  
357  1 Y 1 A ALA 640  ? A ALA 625  
358  1 Y 1 A VAL 641  ? A VAL 626  
359  1 Y 1 A TYR 642  ? A TYR 627  
360  1 Y 1 A TYR 643  ? A TYR 628  
361  1 Y 1 A ASN 644  ? A ASN 629  
362  1 Y 1 A SER 645  ? A SER 630  
363  1 Y 1 A TRP 646  ? A TRP 631  
364  1 Y 1 A GLN 647  ? A GLN 632  
365  1 Y 1 A ASN 648  ? A ASN 633  
366  1 Y 1 A LEU 649  ? A LEU 634  
367  1 Y 1 A LEU 650  ? A LEU 635  
368  1 Y 1 A TYR 651  ? A TYR 636  
369  1 Y 1 A ASP 652  ? A ASP 637  
370  1 Y 1 A SER 653  ? A SER 638  
371  1 Y 1 A ASN 654  ? A ASN 639  
372  1 Y 1 A GLY 655  ? A GLY 640  
373  1 Y 1 A ASN 656  ? A ASN 641  
374  1 Y 1 A ILE 657  ? A ILE 642  
375  1 Y 1 A ILE 658  ? A ILE 643  
376  1 Y 1 A GLY 659  ? A GLY 644  
377  1 Y 1 A PHE 660  ? A PHE 645  
378  1 Y 1 A LYS 661  ? A LYS 646  
379  1 Y 1 A ASP 662  ? A ASP 647  
380  1 Y 1 A PHE 663  ? A PHE 648  
381  1 Y 1 A VAL 664  ? A VAL 649  
382  1 Y 1 A THR 665  ? A THR 650  
383  1 Y 1 A ASN 666  ? A ASN 651  
384  1 Y 1 A LYS 667  ? A LYS 652  
385  1 Y 1 A THR 668  ? A THR 653  
386  1 Y 1 A TYR 669  ? A TYR 654  
387  1 Y 1 A ASN 670  ? A ASN 655  
388  1 Y 1 A ILE 671  ? A ILE 656  
389  1 Y 1 A PHE 672  ? A PHE 657  
390  1 Y 1 A PRO 673  ? A PRO 658  
391  1 Y 1 A CYS 674  ? A CYS 659  
392  1 Y 1 A TYR 675  ? A TYR 660  
393  1 Y 1 A ALA 676  ? A ALA 661  
394  1 Y 1 A GLY 677  ? A GLY 662  
395  1 Y 1 A ARG 678  ? A ARG 663  
396  1 Y 1 A VAL 679  ? A VAL 664  
397  1 Y 1 A SER 680  ? A SER 665  
398  1 Y 1 A ALA 681  ? A ALA 666  
399  1 Y 1 A ALA 682  ? A ALA 667  
400  1 Y 1 A PHE 683  ? A PHE 668  
401  1 Y 1 A HIS 684  ? A HIS 669  
402  1 Y 1 A GLN 685  ? A GLN 670  
403  1 Y 1 A ASN 686  ? A ASN 671  
404  1 Y 1 A ALA 687  ? A ALA 672  
405  1 Y 1 A SER 688  ? A SER 673  
406  1 Y 1 A SER 689  ? A SER 674  
407  1 Y 1 A LEU 690  ? A LEU 675  
408  1 Y 1 A ALA 691  ? A ALA 676  
409  1 Y 1 A LEU 692  ? A LEU 677  
410  1 Y 1 A LEU 693  ? A LEU 678  
411  1 Y 1 A TYR 694  ? A TYR 679  
412  1 Y 1 A ARG 695  ? A ARG 680  
413  1 Y 1 A ASN 696  ? A ASN 681  
414  1 Y 1 A LEU 697  ? A LEU 682  
415  1 Y 1 A LYS 698  ? A LYS 683  
416  1 Y 1 A CYS 699  ? A CYS 684  
417  1 Y 1 A SER 700  ? A SER 685  
418  1 Y 1 A TYR 701  ? A TYR 686  
419  1 Y 1 A VAL 702  ? A VAL 687  
420  1 Y 1 A LEU 703  ? A LEU 688  
421  1 Y 1 A ASN 704  ? A ASN 689  
422  1 Y 1 A ASN 705  ? A ASN 690  
423  1 Y 1 A ILE 706  ? A ILE 691  
424  1 Y 1 A SER 707  ? A SER 692  
425  1 Y 1 A LEU 708  ? A LEU 693  
426  1 Y 1 A THR 709  ? A THR 694  
427  1 Y 1 A THR 710  ? A THR 695  
428  1 Y 1 A GLN 711  ? A GLN 696  
429  1 Y 1 A PRO 712  ? A PRO 697  
430  1 Y 1 A TYR 713  ? A TYR 698  
431  1 Y 1 A PHE 714  ? A PHE 699  
432  1 Y 1 A ASP 715  ? A ASP 700  
433  1 Y 1 A SER 716  ? A SER 701  
434  1 Y 1 A TYR 717  ? A TYR 702  
435  1 Y 1 A LEU 718  ? A LEU 703  
436  1 Y 1 A GLY 719  ? A GLY 704  
437  1 Y 1 A CYS 720  ? A CYS 705  
438  1 Y 1 A VAL 721  ? A VAL 706  
439  1 Y 1 A PHE 722  ? A PHE 707  
440  1 Y 1 A ASN 723  ? A ASN 708  
441  1 Y 1 A ALA 724  ? A ALA 709  
442  1 Y 1 A ASP 725  ? A ASP 710  
443  1 Y 1 A ASN 726  ? A ASN 711  
444  1 Y 1 A LEU 727  ? A LEU 712  
445  1 Y 1 A THR 728  ? A THR 713  
446  1 Y 1 A ASP 729  ? A ASP 714  
447  1 Y 1 A TYR 730  ? A TYR 715  
448  1 Y 1 A SER 731  ? A SER 716  
449  1 Y 1 A VAL 732  ? A VAL 717  
450  1 Y 1 A SER 733  ? A SER 718  
451  1 Y 1 A SER 734  ? A SER 719  
452  1 Y 1 A CYS 735  ? A CYS 720  
453  1 Y 1 A ALA 736  ? A ALA 721  
454  1 Y 1 A LEU 737  ? A LEU 722  
455  1 Y 1 A ARG 738  ? A ARG 723  
456  1 Y 1 A MET 739  ? A MET 724  
457  1 Y 1 A GLY 740  ? A GLY 725  
458  1 Y 1 A SER 741  ? A SER 726  
459  1 Y 1 A GLY 742  ? A GLY 727  
460  1 Y 1 A PHE 743  ? A PHE 728  
461  1 Y 1 A CYS 744  ? A CYS 729  
462  1 Y 1 A VAL 745  ? A VAL 730  
463  1 Y 1 A ASP 746  ? A ASP 731  
464  1 Y 1 A TYR 747  ? A TYR 732  
465  1 Y 1 A ASN 748  ? A ASN 733  
466  1 Y 1 A SER 749  ? A SER 734  
467  1 Y 1 A PRO 750  ? A PRO 735  
468  1 Y 1 A SER 751  ? A SER 736  
469  1 Y 1 A SER 752  ? A SER 737  
470  1 Y 1 A SER 753  ? A SER 738  
471  1 Y 1 A SER 754  ? A SER 739  
472  1 Y 1 A SER 755  ? A SER 740  
473  1 Y 1 A ARG 756  ? A ARG 741  
474  1 Y 1 A ARG 757  ? A ARG 742  
475  1 Y 1 A LYS 758  ? A LYS 743  
476  1 Y 1 A ARG 759  ? A ARG 744  
477  1 Y 1 A ARG 760  ? A ARG 745  
478  1 Y 1 A SER 761  ? A SER 746  
479  1 Y 1 A ILE 762  ? A ILE 747  
480  1 Y 1 A SER 763  ? A SER 748  
481  1 Y 1 A ALA 764  ? A ALA 749  
482  1 Y 1 A SER 765  ? A SER 750  
483  1 Y 1 A TYR 766  ? A TYR 751  
484  1 Y 1 A ARG 767  ? A ARG 752  
485  1 Y 1 A PHE 768  ? A PHE 753  
486  1 Y 1 A VAL 769  ? A VAL 754  
487  1 Y 1 A THR 770  ? A THR 755  
488  1 Y 1 A PHE 771  ? A PHE 756  
489  1 Y 1 A GLU 772  ? A GLU 757  
490  1 Y 1 A PRO 773  ? A PRO 758  
491  1 Y 1 A PHE 774  ? A PHE 759  
492  1 Y 1 A ASN 775  ? A ASN 760  
493  1 Y 1 A VAL 776  ? A VAL 761  
494  1 Y 1 A SER 777  ? A SER 762  
495  1 Y 1 A PHE 778  ? A PHE 763  
496  1 Y 1 A VAL 779  ? A VAL 764  
497  1 Y 1 A ASN 780  ? A ASN 765  
498  1 Y 1 A ASP 781  ? A ASP 766  
499  1 Y 1 A SER 782  ? A SER 767  
500  1 Y 1 A ILE 783  ? A ILE 768  
501  1 Y 1 A GLU 784  ? A GLU 769  
502  1 Y 1 A SER 785  ? A SER 770  
503  1 Y 1 A VAL 786  ? A VAL 771  
504  1 Y 1 A GLY 787  ? A GLY 772  
505  1 Y 1 A GLY 788  ? A GLY 773  
506  1 Y 1 A LEU 789  ? A LEU 774  
507  1 Y 1 A TYR 790  ? A TYR 775  
508  1 Y 1 A GLU 791  ? A GLU 776  
509  1 Y 1 A ILE 792  ? A ILE 777  
510  1 Y 1 A LYS 793  ? A LYS 778  
511  1 Y 1 A ILE 794  ? A ILE 779  
512  1 Y 1 A PRO 795  ? A PRO 780  
513  1 Y 1 A THR 796  ? A THR 781  
514  1 Y 1 A ASN 797  ? A ASN 782  
515  1 Y 1 A PHE 798  ? A PHE 783  
516  1 Y 1 A THR 799  ? A THR 784  
517  1 Y 1 A ILE 800  ? A ILE 785  
518  1 Y 1 A VAL 801  ? A VAL 786  
519  1 Y 1 A GLY 802  ? A GLY 787  
520  1 Y 1 A GLN 803  ? A GLN 788  
521  1 Y 1 A GLU 804  ? A GLU 789  
522  1 Y 1 A GLU 805  ? A GLU 790  
523  1 Y 1 A PHE 806  ? A PHE 791  
524  1 Y 1 A ILE 807  ? A ILE 792  
525  1 Y 1 A GLN 808  ? A GLN 793  
526  1 Y 1 A THR 809  ? A THR 794  
527  1 Y 1 A ASN 810  ? A ASN 795  
528  1 Y 1 A SER 811  ? A SER 796  
529  1 Y 1 A PRO 812  ? A PRO 797  
530  1 Y 1 A LYS 813  ? A LYS 798  
531  1 Y 1 A VAL 814  ? A VAL 799  
532  1 Y 1 A THR 815  ? A THR 800  
533  1 Y 1 A ILE 816  ? A ILE 801  
534  1 Y 1 A ASP 817  ? A ASP 802  
535  1 Y 1 A CYS 818  ? A CYS 803  
536  1 Y 1 A SER 819  ? A SER 804  
537  1 Y 1 A LEU 820  ? A LEU 805  
538  1 Y 1 A PHE 821  ? A PHE 806  
539  1 Y 1 A VAL 822  ? A VAL 807  
540  1 Y 1 A CYS 823  ? A CYS 808  
541  1 Y 1 A SER 824  ? A SER 809  
542  1 Y 1 A ASN 825  ? A ASN 810  
543  1 Y 1 A TYR 826  ? A TYR 811  
544  1 Y 1 A ALA 827  ? A ALA 812  
545  1 Y 1 A ALA 828  ? A ALA 813  
546  1 Y 1 A CYS 829  ? A CYS 814  
547  1 Y 1 A HIS 830  ? A HIS 815  
548  1 Y 1 A ASP 831  ? A ASP 816  
549  1 Y 1 A LEU 832  ? A LEU 817  
550  1 Y 1 A LEU 833  ? A LEU 818  
551  1 Y 1 A SER 834  ? A SER 819  
552  1 Y 1 A GLU 835  ? A GLU 820  
553  1 Y 1 A TYR 836  ? A TYR 821  
554  1 Y 1 A GLY 837  ? A GLY 822  
555  1 Y 1 A THR 838  ? A THR 823  
556  1 Y 1 A PHE 839  ? A PHE 824  
557  1 Y 1 A CYS 840  ? A CYS 825  
558  1 Y 1 A ASP 841  ? A ASP 826  
559  1 Y 1 A ASN 842  ? A ASN 827  
560  1 Y 1 A ILE 843  ? A ILE 828  
561  1 Y 1 A ASN 844  ? A ASN 829  
562  1 Y 1 A SER 845  ? A SER 830  
563  1 Y 1 A ILE 846  ? A ILE 831  
564  1 Y 1 A LEU 847  ? A LEU 832  
565  1 Y 1 A ASP 848  ? A ASP 833  
566  1 Y 1 A GLU 849  ? A GLU 834  
567  1 Y 1 A VAL 850  ? A VAL 835  
568  1 Y 1 A ASN 851  ? A ASN 836  
569  1 Y 1 A GLY 852  ? A GLY 837  
570  1 Y 1 A LEU 853  ? A LEU 838  
571  1 Y 1 A LEU 854  ? A LEU 839  
572  1 Y 1 A ASP 855  ? A ASP 840  
573  1 Y 1 A THR 856  ? A THR 841  
574  1 Y 1 A THR 857  ? A THR 842  
575  1 Y 1 A GLN 858  ? A GLN 843  
576  1 Y 1 A LEU 859  ? A LEU 844  
577  1 Y 1 A HIS 860  ? A HIS 845  
578  1 Y 1 A VAL 861  ? A VAL 846  
579  1 Y 1 A ALA 862  ? A ALA 847  
580  1 Y 1 A ASP 863  ? A ASP 848  
581  1 Y 1 A THR 864  ? A THR 849  
582  1 Y 1 A LEU 865  ? A LEU 850  
583  1 Y 1 A MET 866  ? A MET 851  
584  1 Y 1 A GLN 867  ? A GLN 852  
585  1 Y 1 A GLY 868  ? A GLY 853  
586  1 Y 1 A VAL 869  ? A VAL 854  
587  1 Y 1 A THR 870  ? A THR 855  
588  1 Y 1 A LEU 871  ? A LEU 856  
589  1 Y 1 A SER 872  ? A SER 857  
590  1 Y 1 A SER 873  ? A SER 858  
591  1 Y 1 A ASN 874  ? A ASN 859  
592  1 Y 1 A LEU 875  ? A LEU 860  
593  1 Y 1 A ASN 876  ? A ASN 861  
594  1 Y 1 A THR 877  ? A THR 862  
595  1 Y 1 A ASN 878  ? A ASN 863  
596  1 Y 1 A LEU 879  ? A LEU 864  
597  1 Y 1 A HIS 880  ? A HIS 865  
598  1 Y 1 A PHE 881  ? A PHE 866  
599  1 Y 1 A ASP 882  ? A ASP 867  
600  1 Y 1 A VAL 883  ? A VAL 868  
601  1 Y 1 A ASP 884  ? A ASP 869  
602  1 Y 1 A ASN 885  ? A ASN 870  
603  1 Y 1 A ILE 886  ? A ILE 871  
604  1 Y 1 A ASN 887  ? A ASN 872  
605  1 Y 1 A PHE 888  ? A PHE 873  
606  1 Y 1 A LYS 889  ? A LYS 874  
607  1 Y 1 A SER 890  ? A SER 875  
608  1 Y 1 A LEU 891  ? A LEU 876  
609  1 Y 1 A VAL 892  ? A VAL 877  
610  1 Y 1 A GLY 893  ? A GLY 878  
611  1 Y 1 A CYS 894  ? A CYS 879  
612  1 Y 1 A LEU 895  ? A LEU 880  
613  1 Y 1 A GLY 896  ? A GLY 881  
614  1 Y 1 A PRO 897  ? A PRO 882  
615  1 Y 1 A HIS 898  ? A HIS 883  
616  1 Y 1 A CYS 899  ? A CYS 884  
617  1 Y 1 A GLY 900  ? A GLY 885  
618  1 Y 1 A SER 901  ? A SER 886  
619  1 Y 1 A SER 902  ? A SER 887  
620  1 Y 1 A SER 903  ? A SER 888  
621  1 Y 1 A ARG 904  ? A ARG 889  
622  1 Y 1 A SER 905  ? A SER 890  
623  1 Y 1 A PHE 906  ? A PHE 891  
624  1 Y 1 A PHE 907  ? A PHE 892  
625  1 Y 1 A GLU 908  ? A GLU 893  
626  1 Y 1 A ASP 909  ? A ASP 894  
627  1 Y 1 A LEU 910  ? A LEU 895  
628  1 Y 1 A LEU 911  ? A LEU 896  
629  1 Y 1 A PHE 912  ? A PHE 897  
630  1 Y 1 A ASP 913  ? A ASP 898  
631  1 Y 1 A LYS 914  ? A LYS 899  
632  1 Y 1 A VAL 915  ? A VAL 900  
633  1 Y 1 A LYS 916  ? A LYS 901  
634  1 Y 1 A LEU 917  ? A LEU 902  
635  1 Y 1 A SER 918  ? A SER 903  
636  1 Y 1 A ASP 919  ? A ASP 904  
637  1 Y 1 A VAL 920  ? A VAL 905  
638  1 Y 1 A GLY 921  ? A GLY 906  
639  1 Y 1 A PHE 922  ? A PHE 907  
640  1 Y 1 A VAL 923  ? A VAL 908  
641  1 Y 1 A GLU 924  ? A GLU 909  
642  1 Y 1 A ALA 925  ? A ALA 910  
643  1 Y 1 A TYR 926  ? A TYR 911  
644  1 Y 1 A ASN 927  ? A ASN 912  
645  1 Y 1 A ASN 928  ? A ASN 913  
646  1 Y 1 A CYS 929  ? A CYS 914  
647  1 Y 1 A THR 930  ? A THR 915  
648  1 Y 1 A GLY 931  ? A GLY 916  
649  1 Y 1 A GLY 932  ? A GLY 917  
650  1 Y 1 A SER 933  ? A SER 918  
651  1 Y 1 A GLU 934  ? A GLU 919  
652  1 Y 1 A ILE 935  ? A ILE 920  
653  1 Y 1 A ARG 936  ? A ARG 921  
654  1 Y 1 A ASP 937  ? A ASP 922  
655  1 Y 1 A LEU 938  ? A LEU 923  
656  1 Y 1 A LEU 939  ? A LEU 924  
657  1 Y 1 A CYS 940  ? A CYS 925  
658  1 Y 1 A VAL 941  ? A VAL 926  
659  1 Y 1 A GLN 942  ? A GLN 927  
660  1 Y 1 A SER 943  ? A SER 928  
661  1 Y 1 A PHE 944  ? A PHE 929  
662  1 Y 1 A ASN 945  ? A ASN 930  
663  1 Y 1 A GLY 946  ? A GLY 931  
664  1 Y 1 A ILE 947  ? A ILE 932  
665  1 Y 1 A LYS 948  ? A LYS 933  
666  1 Y 1 A VAL 949  ? A VAL 934  
667  1 Y 1 A LEU 950  ? A LEU 935  
668  1 Y 1 A PRO 951  ? A PRO 936  
669  1 Y 1 A PRO 952  ? A PRO 937  
670  1 Y 1 A ILE 953  ? A ILE 938  
671  1 Y 1 A LEU 954  ? A LEU 939  
672  1 Y 1 A SER 955  ? A SER 940  
673  1 Y 1 A GLU 956  ? A GLU 941  
674  1 Y 1 A SER 957  ? A SER 942  
675  1 Y 1 A GLN 958  ? A GLN 943  
676  1 Y 1 A ILE 959  ? A ILE 944  
677  1 Y 1 A SER 960  ? A SER 945  
678  1 Y 1 A GLY 961  ? A GLY 946  
679  1 Y 1 A TYR 962  ? A TYR 947  
680  1 Y 1 A THR 963  ? A THR 948  
681  1 Y 1 A THR 964  ? A THR 949  
682  1 Y 1 A ALA 965  ? A ALA 950  
683  1 Y 1 A ALA 966  ? A ALA 951  
684  1 Y 1 A THR 967  ? A THR 952  
685  1 Y 1 A VAL 968  ? A VAL 953  
686  1 Y 1 A ALA 969  ? A ALA 954  
687  1 Y 1 A ALA 970  ? A ALA 955  
688  1 Y 1 A MET 971  ? A MET 956  
689  1 Y 1 A PHE 972  ? A PHE 957  
690  1 Y 1 A PRO 973  ? A PRO 958  
691  1 Y 1 A PRO 974  ? A PRO 959  
692  1 Y 1 A TRP 975  ? A TRP 960  
693  1 Y 1 A SER 976  ? A SER 961  
694  1 Y 1 A ALA 977  ? A ALA 962  
695  1 Y 1 A ALA 978  ? A ALA 963  
696  1 Y 1 A ALA 979  ? A ALA 964  
697  1 Y 1 A GLY 980  ? A GLY 965  
698  1 Y 1 A ILE 981  ? A ILE 966  
699  1 Y 1 A PRO 982  ? A PRO 967  
700  1 Y 1 A PHE 983  ? A PHE 968  
701  1 Y 1 A SER 984  ? A SER 969  
702  1 Y 1 A LEU 985  ? A LEU 970  
703  1 Y 1 A ASN 986  ? A ASN 971  
704  1 Y 1 A VAL 987  ? A VAL 972  
705  1 Y 1 A GLN 988  ? A GLN 973  
706  1 Y 1 A TYR 989  ? A TYR 974  
707  1 Y 1 A ARG 990  ? A ARG 975  
708  1 Y 1 A ILE 991  ? A ILE 976  
709  1 Y 1 A ASN 992  ? A ASN 977  
710  1 Y 1 A GLY 993  ? A GLY 978  
711  1 Y 1 A LEU 994  ? A LEU 979  
712  1 Y 1 A GLY 995  ? A GLY 980  
713  1 Y 1 A VAL 996  ? A VAL 981  
714  1 Y 1 A THR 997  ? A THR 982  
715  1 Y 1 A MET 998  ? A MET 983  
716  1 Y 1 A ASP 999  ? A ASP 984  
717  1 Y 1 A VAL 1000 ? A VAL 985  
718  1 Y 1 A LEU 1001 ? A LEU 986  
719  1 Y 1 A ASN 1002 ? A ASN 987  
720  1 Y 1 A LYS 1003 ? A LYS 988  
721  1 Y 1 A ASN 1004 ? A ASN 989  
722  1 Y 1 A GLN 1005 ? A GLN 990  
723  1 Y 1 A LYS 1006 ? A LYS 991  
724  1 Y 1 A LEU 1007 ? A LEU 992  
725  1 Y 1 A ILE 1008 ? A ILE 993  
726  1 Y 1 A ALA 1009 ? A ALA 994  
727  1 Y 1 A THR 1010 ? A THR 995  
728  1 Y 1 A ALA 1011 ? A ALA 996  
729  1 Y 1 A PHE 1012 ? A PHE 997  
730  1 Y 1 A ASN 1013 ? A ASN 998  
731  1 Y 1 A ASN 1014 ? A ASN 999  
732  1 Y 1 A ALA 1015 ? A ALA 1000 
733  1 Y 1 A LEU 1016 ? A LEU 1001 
734  1 Y 1 A LEU 1017 ? A LEU 1002 
735  1 Y 1 A SER 1018 ? A SER 1003 
736  1 Y 1 A ILE 1019 ? A ILE 1004 
737  1 Y 1 A GLN 1020 ? A GLN 1005 
738  1 Y 1 A ASN 1021 ? A ASN 1006 
739  1 Y 1 A GLY 1022 ? A GLY 1007 
740  1 Y 1 A PHE 1023 ? A PHE 1008 
741  1 Y 1 A SER 1024 ? A SER 1009 
742  1 Y 1 A ALA 1025 ? A ALA 1010 
743  1 Y 1 A PRO 1026 ? A PRO 1011 
744  1 Y 1 A ASN 1027 ? A ASN 1012 
745  1 Y 1 A SER 1028 ? A SER 1013 
746  1 Y 1 A ALA 1029 ? A ALA 1014 
747  1 Y 1 A LEU 1030 ? A LEU 1015 
748  1 Y 1 A ALA 1031 ? A ALA 1016 
749  1 Y 1 A LYS 1032 ? A LYS 1017 
750  1 Y 1 A ILE 1033 ? A ILE 1018 
751  1 Y 1 A GLN 1034 ? A GLN 1019 
752  1 Y 1 A SER 1035 ? A SER 1020 
753  1 Y 1 A VAL 1036 ? A VAL 1021 
754  1 Y 1 A VAL 1037 ? A VAL 1022 
755  1 Y 1 A ASN 1038 ? A ASN 1023 
756  1 Y 1 A SER 1039 ? A SER 1024 
757  1 Y 1 A ASN 1040 ? A ASN 1025 
758  1 Y 1 A ALA 1041 ? A ALA 1026 
759  1 Y 1 A GLN 1042 ? A GLN 1027 
760  1 Y 1 A ALA 1043 ? A ALA 1028 
761  1 Y 1 A LEU 1044 ? A LEU 1029 
762  1 Y 1 A ASN 1045 ? A ASN 1030 
763  1 Y 1 A SER 1046 ? A SER 1031 
764  1 Y 1 A LEU 1047 ? A LEU 1032 
765  1 Y 1 A LEU 1048 ? A LEU 1033 
766  1 Y 1 A GLN 1049 ? A GLN 1034 
767  1 Y 1 A GLN 1050 ? A GLN 1035 
768  1 Y 1 A LEU 1051 ? A LEU 1036 
769  1 Y 1 A PHE 1052 ? A PHE 1037 
770  1 Y 1 A ASN 1053 ? A ASN 1038 
771  1 Y 1 A LYS 1054 ? A LYS 1039 
772  1 Y 1 A PHE 1055 ? A PHE 1040 
773  1 Y 1 A GLY 1056 ? A GLY 1041 
774  1 Y 1 A ALA 1057 ? A ALA 1042 
775  1 Y 1 A ILE 1058 ? A ILE 1043 
776  1 Y 1 A SER 1059 ? A SER 1044 
777  1 Y 1 A SER 1060 ? A SER 1045 
778  1 Y 1 A SER 1061 ? A SER 1046 
779  1 Y 1 A LEU 1062 ? A LEU 1047 
780  1 Y 1 A GLN 1063 ? A GLN 1048 
781  1 Y 1 A GLU 1064 ? A GLU 1049 
782  1 Y 1 A ILE 1065 ? A ILE 1050 
783  1 Y 1 A LEU 1066 ? A LEU 1051 
784  1 Y 1 A SER 1067 ? A SER 1052 
785  1 Y 1 A ARG 1068 ? A ARG 1053 
786  1 Y 1 A LEU 1069 ? A LEU 1054 
787  1 Y 1 A ASP 1070 ? A ASP 1055 
788  1 Y 1 A PRO 1071 ? A PRO 1056 
789  1 Y 1 A PRO 1072 ? A PRO 1057 
790  1 Y 1 A GLU 1073 ? A GLU 1058 
791  1 Y 1 A ALA 1074 ? A ALA 1059 
792  1 Y 1 A GLN 1075 ? A GLN 1060 
793  1 Y 1 A VAL 1076 ? A VAL 1061 
794  1 Y 1 A GLN 1077 ? A GLN 1062 
795  1 Y 1 A ILE 1078 ? A ILE 1063 
796  1 Y 1 A ASP 1079 ? A ASP 1064 
797  1 Y 1 A ARG 1080 ? A ARG 1065 
798  1 Y 1 A LEU 1081 ? A LEU 1066 
799  1 Y 1 A ILE 1082 ? A ILE 1067 
800  1 Y 1 A ASN 1083 ? A ASN 1068 
801  1 Y 1 A GLY 1084 ? A GLY 1069 
802  1 Y 1 A ARG 1085 ? A ARG 1070 
803  1 Y 1 A LEU 1086 ? A LEU 1071 
804  1 Y 1 A THR 1087 ? A THR 1072 
805  1 Y 1 A ALA 1088 ? A ALA 1073 
806  1 Y 1 A LEU 1089 ? A LEU 1074 
807  1 Y 1 A ASN 1090 ? A ASN 1075 
808  1 Y 1 A ALA 1091 ? A ALA 1076 
809  1 Y 1 A TYR 1092 ? A TYR 1077 
810  1 Y 1 A VAL 1093 ? A VAL 1078 
811  1 Y 1 A SER 1094 ? A SER 1079 
812  1 Y 1 A GLN 1095 ? A GLN 1080 
813  1 Y 1 A GLN 1096 ? A GLN 1081 
814  1 Y 1 A LEU 1097 ? A LEU 1082 
815  1 Y 1 A SER 1098 ? A SER 1083 
816  1 Y 1 A ASP 1099 ? A ASP 1084 
817  1 Y 1 A ILE 1100 ? A ILE 1085 
818  1 Y 1 A SER 1101 ? A SER 1086 
819  1 Y 1 A LEU 1102 ? A LEU 1087 
820  1 Y 1 A VAL 1103 ? A VAL 1088 
821  1 Y 1 A LYS 1104 ? A LYS 1089 
822  1 Y 1 A PHE 1105 ? A PHE 1090 
823  1 Y 1 A GLY 1106 ? A GLY 1091 
824  1 Y 1 A ALA 1107 ? A ALA 1092 
825  1 Y 1 A ALA 1108 ? A ALA 1093 
826  1 Y 1 A LEU 1109 ? A LEU 1094 
827  1 Y 1 A ALA 1110 ? A ALA 1095 
828  1 Y 1 A MET 1111 ? A MET 1096 
829  1 Y 1 A GLU 1112 ? A GLU 1097 
830  1 Y 1 A LYS 1113 ? A LYS 1098 
831  1 Y 1 A VAL 1114 ? A VAL 1099 
832  1 Y 1 A ASN 1115 ? A ASN 1100 
833  1 Y 1 A GLU 1116 ? A GLU 1101 
834  1 Y 1 A CYS 1117 ? A CYS 1102 
835  1 Y 1 A VAL 1118 ? A VAL 1103 
836  1 Y 1 A LYS 1119 ? A LYS 1104 
837  1 Y 1 A SER 1120 ? A SER 1105 
838  1 Y 1 A GLN 1121 ? A GLN 1106 
839  1 Y 1 A SER 1122 ? A SER 1107 
840  1 Y 1 A PRO 1123 ? A PRO 1108 
841  1 Y 1 A ARG 1124 ? A ARG 1109 
842  1 Y 1 A ILE 1125 ? A ILE 1110 
843  1 Y 1 A ASN 1126 ? A ASN 1111 
844  1 Y 1 A PHE 1127 ? A PHE 1112 
845  1 Y 1 A CYS 1128 ? A CYS 1113 
846  1 Y 1 A GLY 1129 ? A GLY 1114 
847  1 Y 1 A ASN 1130 ? A ASN 1115 
848  1 Y 1 A GLY 1131 ? A GLY 1116 
849  1 Y 1 A ASN 1132 ? A ASN 1117 
850  1 Y 1 A HIS 1133 ? A HIS 1118 
851  1 Y 1 A ILE 1134 ? A ILE 1119 
852  1 Y 1 A LEU 1135 ? A LEU 1120 
853  1 Y 1 A SER 1136 ? A SER 1121 
854  1 Y 1 A LEU 1137 ? A LEU 1122 
855  1 Y 1 A VAL 1138 ? A VAL 1123 
856  1 Y 1 A GLN 1139 ? A GLN 1124 
857  1 Y 1 A ASN 1140 ? A ASN 1125 
858  1 Y 1 A ALA 1141 ? A ALA 1126 
859  1 Y 1 A PRO 1142 ? A PRO 1127 
860  1 Y 1 A TYR 1143 ? A TYR 1128 
861  1 Y 1 A GLY 1144 ? A GLY 1129 
862  1 Y 1 A LEU 1145 ? A LEU 1130 
863  1 Y 1 A LEU 1146 ? A LEU 1131 
864  1 Y 1 A PHE 1147 ? A PHE 1132 
865  1 Y 1 A MET 1148 ? A MET 1133 
866  1 Y 1 A HIS 1149 ? A HIS 1134 
867  1 Y 1 A PHE 1150 ? A PHE 1135 
868  1 Y 1 A SER 1151 ? A SER 1136 
869  1 Y 1 A TYR 1152 ? A TYR 1137 
870  1 Y 1 A LYS 1153 ? A LYS 1138 
871  1 Y 1 A PRO 1154 ? A PRO 1139 
872  1 Y 1 A ILE 1155 ? A ILE 1140 
873  1 Y 1 A SER 1156 ? A SER 1141 
874  1 Y 1 A PHE 1157 ? A PHE 1142 
875  1 Y 1 A LYS 1158 ? A LYS 1143 
876  1 Y 1 A THR 1159 ? A THR 1144 
877  1 Y 1 A VAL 1160 ? A VAL 1145 
878  1 Y 1 A LEU 1161 ? A LEU 1146 
879  1 Y 1 A VAL 1162 ? A VAL 1147 
880  1 Y 1 A SER 1163 ? A SER 1148 
881  1 Y 1 A PRO 1164 ? A PRO 1149 
882  1 Y 1 A GLY 1165 ? A GLY 1150 
883  1 Y 1 A LEU 1166 ? A LEU 1151 
884  1 Y 1 A CYS 1167 ? A CYS 1152 
885  1 Y 1 A ILE 1168 ? A ILE 1153 
886  1 Y 1 A SER 1169 ? A SER 1154 
887  1 Y 1 A GLY 1170 ? A GLY 1155 
888  1 Y 1 A ASP 1171 ? A ASP 1156 
889  1 Y 1 A VAL 1172 ? A VAL 1157 
890  1 Y 1 A GLY 1173 ? A GLY 1158 
891  1 Y 1 A ILE 1174 ? A ILE 1159 
892  1 Y 1 A ALA 1175 ? A ALA 1160 
893  1 Y 1 A PRO 1176 ? A PRO 1161 
894  1 Y 1 A LYS 1177 ? A LYS 1162 
895  1 Y 1 A GLN 1178 ? A GLN 1163 
896  1 Y 1 A GLY 1179 ? A GLY 1164 
897  1 Y 1 A TYR 1180 ? A TYR 1165 
898  1 Y 1 A PHE 1181 ? A PHE 1166 
899  1 Y 1 A ILE 1182 ? A ILE 1167 
900  1 Y 1 A LYS 1183 ? A LYS 1168 
901  1 Y 1 A HIS 1184 ? A HIS 1169 
902  1 Y 1 A ASN 1185 ? A ASN 1170 
903  1 Y 1 A ASP 1186 ? A ASP 1171 
904  1 Y 1 A HIS 1187 ? A HIS 1172 
905  1 Y 1 A TRP 1188 ? A TRP 1173 
906  1 Y 1 A MET 1189 ? A MET 1174 
907  1 Y 1 A PHE 1190 ? A PHE 1175 
908  1 Y 1 A THR 1191 ? A THR 1176 
909  1 Y 1 A GLY 1192 ? A GLY 1177 
910  1 Y 1 A SER 1193 ? A SER 1178 
911  1 Y 1 A SER 1194 ? A SER 1179 
912  1 Y 1 A TYR 1195 ? A TYR 1180 
913  1 Y 1 A TYR 1196 ? A TYR 1181 
914  1 Y 1 A TYR 1197 ? A TYR 1182 
915  1 Y 1 A PRO 1198 ? A PRO 1183 
916  1 Y 1 A GLU 1199 ? A GLU 1184 
917  1 Y 1 A PRO 1200 ? A PRO 1185 
918  1 Y 1 A ILE 1201 ? A ILE 1186 
919  1 Y 1 A SER 1202 ? A SER 1187 
920  1 Y 1 A ASP 1203 ? A ASP 1188 
921  1 Y 1 A LYS 1204 ? A LYS 1189 
922  1 Y 1 A ASN 1205 ? A ASN 1190 
923  1 Y 1 A VAL 1206 ? A VAL 1191 
924  1 Y 1 A VAL 1207 ? A VAL 1192 
925  1 Y 1 A PHE 1208 ? A PHE 1193 
926  1 Y 1 A MET 1209 ? A MET 1194 
927  1 Y 1 A ASN 1210 ? A ASN 1195 
928  1 Y 1 A THR 1211 ? A THR 1196 
929  1 Y 1 A CYS 1212 ? A CYS 1197 
930  1 Y 1 A SER 1213 ? A SER 1198 
931  1 Y 1 A VAL 1214 ? A VAL 1199 
932  1 Y 1 A ASN 1215 ? A ASN 1200 
933  1 Y 1 A PHE 1216 ? A PHE 1201 
934  1 Y 1 A THR 1217 ? A THR 1202 
935  1 Y 1 A LYS 1218 ? A LYS 1203 
936  1 Y 1 A ALA 1219 ? A ALA 1204 
937  1 Y 1 A PRO 1220 ? A PRO 1205 
938  1 Y 1 A LEU 1221 ? A LEU 1206 
939  1 Y 1 A VAL 1222 ? A VAL 1207 
940  1 Y 1 A TYR 1223 ? A TYR 1208 
941  1 Y 1 A LEU 1224 ? A LEU 1209 
942  1 Y 1 A ASN 1225 ? A ASN 1210 
943  1 Y 1 A HIS 1226 ? A HIS 1211 
944  1 Y 1 A SER 1227 ? A SER 1212 
945  1 Y 1 A VAL 1228 ? A VAL 1213 
946  1 Y 1 A PRO 1229 ? A PRO 1214 
947  1 Y 1 A LYS 1230 ? A LYS 1215 
948  1 Y 1 A LEU 1231 ? A LEU 1216 
949  1 Y 1 A SER 1232 ? A SER 1217 
950  1 Y 1 A ASP 1233 ? A ASP 1218 
951  1 Y 1 A PHE 1234 ? A PHE 1219 
952  1 Y 1 A GLU 1235 ? A GLU 1220 
953  1 Y 1 A SER 1236 ? A SER 1221 
954  1 Y 1 A GLU 1237 ? A GLU 1222 
955  1 Y 1 A LEU 1238 ? A LEU 1223 
956  1 Y 1 A SER 1239 ? A SER 1224 
957  1 Y 1 A HIS 1240 ? A HIS 1225 
958  1 Y 1 A TRP 1241 ? A TRP 1226 
959  1 Y 1 A PHE 1242 ? A PHE 1227 
960  1 Y 1 A LYS 1243 ? A LYS 1228 
961  1 Y 1 A ASN 1244 ? A ASN 1229 
962  1 Y 1 A GLN 1245 ? A GLN 1230 
963  1 Y 1 A THR 1246 ? A THR 1231 
964  1 Y 1 A SER 1247 ? A SER 1232 
965  1 Y 1 A ILE 1248 ? A ILE 1233 
966  1 Y 1 A ALA 1249 ? A ALA 1234 
967  1 Y 1 A PRO 1250 ? A PRO 1235 
968  1 Y 1 A ASN 1251 ? A ASN 1236 
969  1 Y 1 A LEU 1252 ? A LEU 1237 
970  1 Y 1 A THR 1253 ? A THR 1238 
971  1 Y 1 A LEU 1254 ? A LEU 1239 
972  1 Y 1 A ASN 1255 ? A ASN 1240 
973  1 Y 1 A LEU 1256 ? A LEU 1241 
974  1 Y 1 A HIS 1257 ? A HIS 1242 
975  1 Y 1 A THR 1258 ? A THR 1243 
976  1 Y 1 A ILE 1259 ? A ILE 1244 
977  1 Y 1 A ASN 1260 ? A ASN 1245 
978  1 Y 1 A ALA 1261 ? A ALA 1246 
979  1 Y 1 A THR 1262 ? A THR 1247 
980  1 Y 1 A PHE 1263 ? A PHE 1248 
981  1 Y 1 A LEU 1264 ? A LEU 1249 
982  1 Y 1 A ASP 1265 ? A ASP 1250 
983  1 Y 1 A LEU 1266 ? A LEU 1251 
984  1 Y 1 A TYR 1267 ? A TYR 1252 
985  1 Y 1 A TYR 1268 ? A TYR 1253 
986  1 Y 1 A GLU 1269 ? A GLU 1254 
987  1 Y 1 A MET 1270 ? A MET 1255 
988  1 Y 1 A ASN 1271 ? A ASN 1256 
989  1 Y 1 A LEU 1272 ? A LEU 1257 
990  1 Y 1 A ILE 1273 ? A ILE 1258 
991  1 Y 1 A GLN 1274 ? A GLN 1259 
992  1 Y 1 A GLU 1275 ? A GLU 1260 
993  1 Y 1 A SER 1276 ? A SER 1261 
994  1 Y 1 A ILE 1277 ? A ILE 1262 
995  1 Y 1 A LYS 1278 ? A LYS 1263 
996  1 Y 1 A SER 1279 ? A SER 1264 
997  1 Y 1 A LEU 1280 ? A LEU 1265 
998  1 Y 1 A ASN 1281 ? A ASN 1266 
999  1 Y 1 A ASN 1282 ? A ASN 1267 
1000 1 Y 1 A SER 1283 ? A SER 1268 
1001 1 Y 1 A TYR 1284 ? A TYR 1269 
1002 1 Y 1 A ILE 1285 ? A ILE 1270 
1003 1 Y 1 A ASN 1286 ? A ASN 1271 
1004 1 Y 1 A LEU 1287 ? A LEU 1272 
1005 1 Y 1 A LYS 1288 ? A LYS 1273 
1006 1 Y 1 A ASP 1289 ? A ASP 1274 
1007 1 Y 1 A ILE 1290 ? A ILE 1275 
1008 1 Y 1 A GLY 1291 ? A GLY 1276 
1009 1 Y 1 A THR 1292 ? A THR 1277 
1010 1 Y 1 A TYR 1293 ? A TYR 1278 
1011 1 Y 1 A GLU 1294 ? A GLU 1279 
1012 1 Y 1 A MET 1295 ? A MET 1280 
1013 1 Y 1 A TYR 1296 ? A TYR 1281 
1014 1 Y 1 A VAL 1297 ? A VAL 1282 
1015 1 Y 1 A LYS 1298 ? A LYS 1283 
1016 1 Y 1 A SER 1299 ? A SER 1284 
1017 1 Y 1 A GLY 1300 ? A GLY 1285 
1018 1 Y 1 A GLY 1301 ? A GLY 1286 
1019 1 Y 1 A TYR 1302 ? A TYR 1287 
1020 1 Y 1 A ILE 1303 ? A ILE 1288 
1021 1 Y 1 A PRO 1304 ? A PRO 1289 
1022 1 Y 1 A GLU 1305 ? A GLU 1290 
1023 1 Y 1 A ALA 1306 ? A ALA 1291 
1024 1 Y 1 A PRO 1307 ? A PRO 1292 
1025 1 Y 1 A ARG 1308 ? A ARG 1293 
1026 1 Y 1 A ASP 1309 ? A ASP 1294 
1027 1 Y 1 A GLY 1310 ? A GLY 1295 
1028 1 Y 1 A GLN 1311 ? A GLN 1296 
1029 1 Y 1 A ALA 1312 ? A ALA 1297 
1030 1 Y 1 A TYR 1313 ? A TYR 1298 
1031 1 Y 1 A VAL 1314 ? A VAL 1299 
1032 1 Y 1 A ARG 1315 ? A ARG 1300 
1033 1 Y 1 A LYS 1316 ? A LYS 1301 
1034 1 Y 1 A ASP 1317 ? A ASP 1302 
1035 1 Y 1 A GLY 1318 ? A GLY 1303 
1036 1 Y 1 A GLU 1319 ? A GLU 1304 
1037 1 Y 1 A TRP 1320 ? A TRP 1305 
1038 1 Y 1 A VAL 1321 ? A VAL 1306 
1039 1 Y 1 A LEU 1322 ? A LEU 1307 
1040 1 Y 1 A LEU 1323 ? A LEU 1308 
1041 1 Y 1 A SER 1324 ? A SER 1309 
1042 1 Y 1 A THR 1325 ? A THR 1310 
1043 1 Y 1 A PHE 1326 ? A PHE 1311 
1044 1 Y 1 A LEU 1327 ? A LEU 1312 
1045 1 Y 1 A ASN 1328 ? A ASN 1313 
1046 1 Y 1 A SER 1329 ? A SER 1314 
1047 1 Y 1 A GLY 1330 ? A GLY 1315 
1048 1 Y 1 A ARG 1331 ? A ARG 1316 
1049 1 Y 1 A ALA 1332 ? A ALA 1317 
1050 1 Y 1 A HIS 1333 ? A HIS 1318 
1051 1 Y 1 A HIS 1334 ? A HIS 1319 
1052 1 Y 1 A HIS 1335 ? A HIS 1320 
1053 1 Y 1 A HIS 1336 ? A HIS 1321 
1054 1 Y 1 A HIS 1337 ? A HIS 1322 
1055 1 Y 1 A HIS 1338 ? A HIS 1323 
1056 1 Y 1 A GLY 1339 ? A GLY 1324 
1057 1 Y 1 A ALA 1340 ? A ALA 1325 
1058 1 Y 1 A GLY 1341 ? A GLY 1326 
1059 1 Y 1 A GLY 1342 ? A GLY 1327 
1060 1 Y 1 A LEU 1343 ? A LEU 1328 
1061 1 Y 1 A ASN 1344 ? A ASN 1329 
1062 1 Y 1 A ASP 1345 ? A ASP 1330 
1063 1 Y 1 A ILE 1346 ? A ILE 1331 
1064 1 Y 1 A PHE 1347 ? A PHE 1332 
1065 1 Y 1 A GLU 1348 ? A GLU 1333 
1066 1 Y 1 A ALA 1349 ? A ALA 1334 
1067 1 Y 1 A GLN 1350 ? A GLN 1335 
1068 1 Y 1 A LYS 1351 ? A LYS 1336 
1069 1 Y 1 A ILE 1352 ? A ILE 1337 
1070 1 Y 1 A GLU 1353 ? A GLU 1338 
1071 1 Y 1 A TRP 1354 ? A TRP 1339 
1072 1 Y 1 A HIS 1355 ? A HIS 1340 
1073 1 Y 1 A GLU 1356 ? A GLU 1341 
1074 1 Y 1 A ASP 1357 ? A ASP 1342 
1075 1 Y 1 A THR 1358 ? A THR 1343 
1076 1 Y 1 A ALA 1359 ? A ALA 1344 
1077 1 Y 1 A ALA 1360 ? A ALA 1345 
1078 1 Y 1 A ALA 1361 ? A ALA 1346 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MAN C1   C N S 251 
MAN C2   C N S 252 
MAN C3   C N S 253 
MAN C4   C N S 254 
MAN C5   C N R 255 
MAN C6   C N N 256 
MAN O1   O N N 257 
MAN O2   O N N 258 
MAN O3   O N N 259 
MAN O4   O N N 260 
MAN O5   O N N 261 
MAN O6   O N N 262 
MAN H1   H N N 263 
MAN H2   H N N 264 
MAN H3   H N N 265 
MAN H4   H N N 266 
MAN H5   H N N 267 
MAN H61  H N N 268 
MAN H62  H N N 269 
MAN HO1  H N N 270 
MAN HO2  H N N 271 
MAN HO3  H N N 272 
MAN HO4  H N N 273 
MAN HO6  H N N 274 
MET N    N N N 275 
MET CA   C N S 276 
MET C    C N N 277 
MET O    O N N 278 
MET CB   C N N 279 
MET CG   C N N 280 
MET SD   S N N 281 
MET CE   C N N 282 
MET OXT  O N N 283 
MET H    H N N 284 
MET H2   H N N 285 
MET HA   H N N 286 
MET HB2  H N N 287 
MET HB3  H N N 288 
MET HG2  H N N 289 
MET HG3  H N N 290 
MET HE1  H N N 291 
MET HE2  H N N 292 
MET HE3  H N N 293 
MET HXT  H N N 294 
NAG C1   C N R 295 
NAG C2   C N R 296 
NAG C3   C N R 297 
NAG C4   C N S 298 
NAG C5   C N R 299 
NAG C6   C N N 300 
NAG C7   C N N 301 
NAG C8   C N N 302 
NAG N2   N N N 303 
NAG O1   O N N 304 
NAG O3   O N N 305 
NAG O4   O N N 306 
NAG O5   O N N 307 
NAG O6   O N N 308 
NAG O7   O N N 309 
NAG H1   H N N 310 
NAG H2   H N N 311 
NAG H3   H N N 312 
NAG H4   H N N 313 
NAG H5   H N N 314 
NAG H61  H N N 315 
NAG H62  H N N 316 
NAG H81  H N N 317 
NAG H82  H N N 318 
NAG H83  H N N 319 
NAG HN2  H N N 320 
NAG HO1  H N N 321 
NAG HO3  H N N 322 
NAG HO4  H N N 323 
NAG HO6  H N N 324 
PHE N    N N N 325 
PHE CA   C N S 326 
PHE C    C N N 327 
PHE O    O N N 328 
PHE CB   C N N 329 
PHE CG   C Y N 330 
PHE CD1  C Y N 331 
PHE CD2  C Y N 332 
PHE CE1  C Y N 333 
PHE CE2  C Y N 334 
PHE CZ   C Y N 335 
PHE OXT  O N N 336 
PHE H    H N N 337 
PHE H2   H N N 338 
PHE HA   H N N 339 
PHE HB2  H N N 340 
PHE HB3  H N N 341 
PHE HD1  H N N 342 
PHE HD2  H N N 343 
PHE HE1  H N N 344 
PHE HE2  H N N 345 
PHE HZ   H N N 346 
PHE HXT  H N N 347 
PRO N    N N N 348 
PRO CA   C N S 349 
PRO C    C N N 350 
PRO O    O N N 351 
PRO CB   C N N 352 
PRO CG   C N N 353 
PRO CD   C N N 354 
PRO OXT  O N N 355 
PRO H    H N N 356 
PRO HA   H N N 357 
PRO HB2  H N N 358 
PRO HB3  H N N 359 
PRO HG2  H N N 360 
PRO HG3  H N N 361 
PRO HD2  H N N 362 
PRO HD3  H N N 363 
PRO HXT  H N N 364 
SER N    N N N 365 
SER CA   C N S 366 
SER C    C N N 367 
SER O    O N N 368 
SER CB   C N N 369 
SER OG   O N N 370 
SER OXT  O N N 371 
SER H    H N N 372 
SER H2   H N N 373 
SER HA   H N N 374 
SER HB2  H N N 375 
SER HB3  H N N 376 
SER HG   H N N 377 
SER HXT  H N N 378 
THR N    N N N 379 
THR CA   C N S 380 
THR C    C N N 381 
THR O    O N N 382 
THR CB   C N R 383 
THR OG1  O N N 384 
THR CG2  C N N 385 
THR OXT  O N N 386 
THR H    H N N 387 
THR H2   H N N 388 
THR HA   H N N 389 
THR HB   H N N 390 
THR HG1  H N N 391 
THR HG21 H N N 392 
THR HG22 H N N 393 
THR HG23 H N N 394 
THR HXT  H N N 395 
TRP N    N N N 396 
TRP CA   C N S 397 
TRP C    C N N 398 
TRP O    O N N 399 
TRP CB   C N N 400 
TRP CG   C Y N 401 
TRP CD1  C Y N 402 
TRP CD2  C Y N 403 
TRP NE1  N Y N 404 
TRP CE2  C Y N 405 
TRP CE3  C Y N 406 
TRP CZ2  C Y N 407 
TRP CZ3  C Y N 408 
TRP CH2  C Y N 409 
TRP OXT  O N N 410 
TRP H    H N N 411 
TRP H2   H N N 412 
TRP HA   H N N 413 
TRP HB2  H N N 414 
TRP HB3  H N N 415 
TRP HD1  H N N 416 
TRP HE1  H N N 417 
TRP HE3  H N N 418 
TRP HZ2  H N N 419 
TRP HZ3  H N N 420 
TRP HH2  H N N 421 
TRP HXT  H N N 422 
TYR N    N N N 423 
TYR CA   C N S 424 
TYR C    C N N 425 
TYR O    O N N 426 
TYR CB   C N N 427 
TYR CG   C Y N 428 
TYR CD1  C Y N 429 
TYR CD2  C Y N 430 
TYR CE1  C Y N 431 
TYR CE2  C Y N 432 
TYR CZ   C Y N 433 
TYR OH   O N N 434 
TYR OXT  O N N 435 
TYR H    H N N 436 
TYR H2   H N N 437 
TYR HA   H N N 438 
TYR HB2  H N N 439 
TYR HB3  H N N 440 
TYR HD1  H N N 441 
TYR HD2  H N N 442 
TYR HE1  H N N 443 
TYR HE2  H N N 444 
TYR HH   H N N 445 
TYR HXT  H N N 446 
VAL N    N N N 447 
VAL CA   C N S 448 
VAL C    C N N 449 
VAL O    O N N 450 
VAL CB   C N N 451 
VAL CG1  C N N 452 
VAL CG2  C N N 453 
VAL OXT  O N N 454 
VAL H    H N N 455 
VAL H2   H N N 456 
VAL HA   H N N 457 
VAL HB   H N N 458 
VAL HG11 H N N 459 
VAL HG12 H N N 460 
VAL HG13 H N N 461 
VAL HG21 H N N 462 
VAL HG22 H N N 463 
VAL HG23 H N N 464 
VAL HXT  H N N 465 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MAN C1  C2   sing N N 240 
MAN C1  O1   sing N N 241 
MAN C1  O5   sing N N 242 
MAN C1  H1   sing N N 243 
MAN C2  C3   sing N N 244 
MAN C2  O2   sing N N 245 
MAN C2  H2   sing N N 246 
MAN C3  C4   sing N N 247 
MAN C3  O3   sing N N 248 
MAN C3  H3   sing N N 249 
MAN C4  C5   sing N N 250 
MAN C4  O4   sing N N 251 
MAN C4  H4   sing N N 252 
MAN C5  C6   sing N N 253 
MAN C5  O5   sing N N 254 
MAN C5  H5   sing N N 255 
MAN C6  O6   sing N N 256 
MAN C6  H61  sing N N 257 
MAN C6  H62  sing N N 258 
MAN O1  HO1  sing N N 259 
MAN O2  HO2  sing N N 260 
MAN O3  HO3  sing N N 261 
MAN O4  HO4  sing N N 262 
MAN O6  HO6  sing N N 263 
MET N   CA   sing N N 264 
MET N   H    sing N N 265 
MET N   H2   sing N N 266 
MET CA  C    sing N N 267 
MET CA  CB   sing N N 268 
MET CA  HA   sing N N 269 
MET C   O    doub N N 270 
MET C   OXT  sing N N 271 
MET CB  CG   sing N N 272 
MET CB  HB2  sing N N 273 
MET CB  HB3  sing N N 274 
MET CG  SD   sing N N 275 
MET CG  HG2  sing N N 276 
MET CG  HG3  sing N N 277 
MET SD  CE   sing N N 278 
MET CE  HE1  sing N N 279 
MET CE  HE2  sing N N 280 
MET CE  HE3  sing N N 281 
MET OXT HXT  sing N N 282 
NAG C1  C2   sing N N 283 
NAG C1  O1   sing N N 284 
NAG C1  O5   sing N N 285 
NAG C1  H1   sing N N 286 
NAG C2  C3   sing N N 287 
NAG C2  N2   sing N N 288 
NAG C2  H2   sing N N 289 
NAG C3  C4   sing N N 290 
NAG C3  O3   sing N N 291 
NAG C3  H3   sing N N 292 
NAG C4  C5   sing N N 293 
NAG C4  O4   sing N N 294 
NAG C4  H4   sing N N 295 
NAG C5  C6   sing N N 296 
NAG C5  O5   sing N N 297 
NAG C5  H5   sing N N 298 
NAG C6  O6   sing N N 299 
NAG C6  H61  sing N N 300 
NAG C6  H62  sing N N 301 
NAG C7  C8   sing N N 302 
NAG C7  N2   sing N N 303 
NAG C7  O7   doub N N 304 
NAG C8  H81  sing N N 305 
NAG C8  H82  sing N N 306 
NAG C8  H83  sing N N 307 
NAG N2  HN2  sing N N 308 
NAG O1  HO1  sing N N 309 
NAG O3  HO3  sing N N 310 
NAG O4  HO4  sing N N 311 
NAG O6  HO6  sing N N 312 
PHE N   CA   sing N N 313 
PHE N   H    sing N N 314 
PHE N   H2   sing N N 315 
PHE CA  C    sing N N 316 
PHE CA  CB   sing N N 317 
PHE CA  HA   sing N N 318 
PHE C   O    doub N N 319 
PHE C   OXT  sing N N 320 
PHE CB  CG   sing N N 321 
PHE CB  HB2  sing N N 322 
PHE CB  HB3  sing N N 323 
PHE CG  CD1  doub Y N 324 
PHE CG  CD2  sing Y N 325 
PHE CD1 CE1  sing Y N 326 
PHE CD1 HD1  sing N N 327 
PHE CD2 CE2  doub Y N 328 
PHE CD2 HD2  sing N N 329 
PHE CE1 CZ   doub Y N 330 
PHE CE1 HE1  sing N N 331 
PHE CE2 CZ   sing Y N 332 
PHE CE2 HE2  sing N N 333 
PHE CZ  HZ   sing N N 334 
PHE OXT HXT  sing N N 335 
PRO N   CA   sing N N 336 
PRO N   CD   sing N N 337 
PRO N   H    sing N N 338 
PRO CA  C    sing N N 339 
PRO CA  CB   sing N N 340 
PRO CA  HA   sing N N 341 
PRO C   O    doub N N 342 
PRO C   OXT  sing N N 343 
PRO CB  CG   sing N N 344 
PRO CB  HB2  sing N N 345 
PRO CB  HB3  sing N N 346 
PRO CG  CD   sing N N 347 
PRO CG  HG2  sing N N 348 
PRO CG  HG3  sing N N 349 
PRO CD  HD2  sing N N 350 
PRO CD  HD3  sing N N 351 
PRO OXT HXT  sing N N 352 
SER N   CA   sing N N 353 
SER N   H    sing N N 354 
SER N   H2   sing N N 355 
SER CA  C    sing N N 356 
SER CA  CB   sing N N 357 
SER CA  HA   sing N N 358 
SER C   O    doub N N 359 
SER C   OXT  sing N N 360 
SER CB  OG   sing N N 361 
SER CB  HB2  sing N N 362 
SER CB  HB3  sing N N 363 
SER OG  HG   sing N N 364 
SER OXT HXT  sing N N 365 
THR N   CA   sing N N 366 
THR N   H    sing N N 367 
THR N   H2   sing N N 368 
THR CA  C    sing N N 369 
THR CA  CB   sing N N 370 
THR CA  HA   sing N N 371 
THR C   O    doub N N 372 
THR C   OXT  sing N N 373 
THR CB  OG1  sing N N 374 
THR CB  CG2  sing N N 375 
THR CB  HB   sing N N 376 
THR OG1 HG1  sing N N 377 
THR CG2 HG21 sing N N 378 
THR CG2 HG22 sing N N 379 
THR CG2 HG23 sing N N 380 
THR OXT HXT  sing N N 381 
TRP N   CA   sing N N 382 
TRP N   H    sing N N 383 
TRP N   H2   sing N N 384 
TRP CA  C    sing N N 385 
TRP CA  CB   sing N N 386 
TRP CA  HA   sing N N 387 
TRP C   O    doub N N 388 
TRP C   OXT  sing N N 389 
TRP CB  CG   sing N N 390 
TRP CB  HB2  sing N N 391 
TRP CB  HB3  sing N N 392 
TRP CG  CD1  doub Y N 393 
TRP CG  CD2  sing Y N 394 
TRP CD1 NE1  sing Y N 395 
TRP CD1 HD1  sing N N 396 
TRP CD2 CE2  doub Y N 397 
TRP CD2 CE3  sing Y N 398 
TRP NE1 CE2  sing Y N 399 
TRP NE1 HE1  sing N N 400 
TRP CE2 CZ2  sing Y N 401 
TRP CE3 CZ3  doub Y N 402 
TRP CE3 HE3  sing N N 403 
TRP CZ2 CH2  doub Y N 404 
TRP CZ2 HZ2  sing N N 405 
TRP CZ3 CH2  sing Y N 406 
TRP CZ3 HZ3  sing N N 407 
TRP CH2 HH2  sing N N 408 
TRP OXT HXT  sing N N 409 
TYR N   CA   sing N N 410 
TYR N   H    sing N N 411 
TYR N   H2   sing N N 412 
TYR CA  C    sing N N 413 
TYR CA  CB   sing N N 414 
TYR CA  HA   sing N N 415 
TYR C   O    doub N N 416 
TYR C   OXT  sing N N 417 
TYR CB  CG   sing N N 418 
TYR CB  HB2  sing N N 419 
TYR CB  HB3  sing N N 420 
TYR CG  CD1  doub Y N 421 
TYR CG  CD2  sing Y N 422 
TYR CD1 CE1  sing Y N 423 
TYR CD1 HD1  sing N N 424 
TYR CD2 CE2  doub Y N 425 
TYR CD2 HD2  sing N N 426 
TYR CE1 CZ   doub Y N 427 
TYR CE1 HE1  sing N N 428 
TYR CE2 CZ   sing Y N 429 
TYR CE2 HE2  sing N N 430 
TYR CZ  OH   sing N N 431 
TYR OH  HH   sing N N 432 
TYR OXT HXT  sing N N 433 
VAL N   CA   sing N N 434 
VAL N   H    sing N N 435 
VAL N   H2   sing N N 436 
VAL CA  C    sing N N 437 
VAL CA  CB   sing N N 438 
VAL CA  HA   sing N N 439 
VAL C   O    doub N N 440 
VAL C   OXT  sing N N 441 
VAL CB  CG1  sing N N 442 
VAL CB  CG2  sing N N 443 
VAL CB  HB   sing N N 444 
VAL CG1 HG11 sing N N 445 
VAL CG1 HG12 sing N N 446 
VAL CG1 HG13 sing N N 447 
VAL CG2 HG21 sing N N 448 
VAL CG2 HG22 sing N N 449 
VAL CG2 HG23 sing N N 450 
VAL OXT HXT  sing N N 451 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-01-24 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9N17 
_em_admin.last_update        2025-05-21 
_em_admin.map_release_date   2025-05-14 
_em_admin.title              'Cryo-EM structure of HCoV-HKU1 glycoprotein D1 Domain (Deletion 33Pro34Arg)' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 10 mM C4H11NO3 1 Tris 
1 50 mM NaCl     2 NaCl 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.457593 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          290028 
_em_entity_assembly_naturalsource.organism             'Human coronavirus HKU1' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         36 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? 1 ? Coot   ? 
OTHER                           ? 8  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 9  ? 1 ? PHENIX ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           1.15 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Canadian Institutes of Health Research (CIHR)' 
_pdbx_audit_support.country                Canada 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
2 MAN 4 n 
2 MAN 5 n 
3 NAG 1 n 
3 NAG 2 n 
# 
_atom_sites.entry_id                    9N17 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . VAL A 1 1   ? 200.075 150.785 190.726 1.00 146.94 ? 14   VAL A N    1 
ATOM   2    C CA   . VAL A 1 1   ? 200.198 149.414 191.287 1.00 145.88 ? 14   VAL A CA   1 
ATOM   3    C C    . VAL A 1 1   ? 198.944 148.615 190.956 1.00 149.19 ? 14   VAL A C    1 
ATOM   4    O O    . VAL A 1 1   ? 197.852 149.175 190.923 1.00 145.08 ? 14   VAL A O    1 
ATOM   5    C CB   . VAL A 1 1   ? 200.459 149.415 192.802 1.00 148.50 ? 14   VAL A CB   1 
ATOM   6    C CG1  . VAL A 1 1   ? 201.769 150.123 193.139 1.00 145.51 ? 14   VAL A CG1  1 
ATOM   7    C CG2  . VAL A 1 1   ? 199.355 150.060 193.648 1.00 150.82 ? 14   VAL A CG2  1 
ATOM   8    H H1   . VAL A 1 1   ? 199.985 150.746 189.721 1.00 148.53 ? 14   VAL A H1   1 
ATOM   9    H H2   . VAL A 1 1   ? 200.879 151.347 190.965 1.00 147.59 ? 14   VAL A H2   1 
ATOM   10   H H3   . VAL A 1 1   ? 199.247 151.233 191.093 1.00 148.44 ? 14   VAL A H3   1 
ATOM   11   H HA   . VAL A 1 1   ? 201.043 148.910 190.817 1.00 147.76 ? 14   VAL A HA   1 
ATOM   12   H HB   . VAL A 1 1   ? 200.571 148.382 193.132 1.00 148.41 ? 14   VAL A HB   1 
ATOM   13   H HG11 . VAL A 1 1   ? 202.585 149.685 192.563 1.00 147.09 ? 14   VAL A HG11 1 
ATOM   14   H HG12 . VAL A 1 1   ? 201.993 149.980 194.196 1.00 148.52 ? 14   VAL A HG12 1 
ATOM   15   H HG13 . VAL A 1 1   ? 201.709 151.194 192.947 1.00 147.47 ? 14   VAL A HG13 1 
ATOM   16   H HG21 . VAL A 1 1   ? 199.619 149.978 194.702 1.00 148.35 ? 14   VAL A HG21 1 
ATOM   17   H HG22 . VAL A 1 1   ? 198.410 149.535 193.509 1.00 148.45 ? 14   VAL A HG22 1 
ATOM   18   H HG23 . VAL A 1 1   ? 199.231 151.116 193.407 1.00 148.38 ? 14   VAL A HG23 1 
ATOM   19   N N    . ILE A 1 2   ? 199.077 147.311 190.724 1.00 152.04 ? 15   ILE A N    1 
ATOM   20   C CA   . ILE A 1 2   ? 197.978 146.355 190.959 1.00 145.92 ? 15   ILE A CA   1 
ATOM   21   C C    . ILE A 1 2   ? 197.951 146.128 192.483 1.00 149.27 ? 15   ILE A C    1 
ATOM   22   O O    . ILE A 1 2   ? 198.933 146.443 193.139 1.00 153.03 ? 15   ILE A O    1 
ATOM   23   C CB   . ILE A 1 2   ? 198.253 145.025 190.227 1.00 148.76 ? 15   ILE A CB   1 
ATOM   24   C CG1  . ILE A 1 2   ? 198.879 145.213 188.835 1.00 151.42 ? 15   ILE A CG1  1 
ATOM   25   C CG2  . ILE A 1 2   ? 196.984 144.165 190.135 1.00 144.88 ? 15   ILE A CG2  1 
ATOM   26   C CD1  . ILE A 1 2   ? 198.005 145.998 187.852 1.00 151.01 ? 15   ILE A CD1  1 
ATOM   27   H H    . ILE A 1 2   ? 200.005 146.919 190.805 1.00 150.06 ? 15   ILE A H    1 
ATOM   28   H HA   . ILE A 1 2   ? 197.028 146.772 190.628 1.00 148.11 ? 15   ILE A HA   1 
ATOM   29   H HB   . ILE A 1 2   ? 198.983 144.468 190.815 1.00 149.72 ? 15   ILE A HB   1 
ATOM   30   H HG12 . ILE A 1 2   ? 199.839 145.718 188.937 1.00 149.58 ? 15   ILE A HG12 1 
ATOM   31   H HG13 . ILE A 1 2   ? 199.079 144.231 188.406 1.00 149.60 ? 15   ILE A HG13 1 
ATOM   32   H HG21 . ILE A 1 2   ? 196.163 144.735 189.701 1.00 148.41 ? 15   ILE A HG21 1 
ATOM   33   H HG22 . ILE A 1 2   ? 196.690 143.806 191.122 1.00 149.06 ? 15   ILE A HG22 1 
ATOM   34   H HG23 . ILE A 1 2   ? 197.172 143.293 189.509 1.00 148.82 ? 15   ILE A HG23 1 
ATOM   35   H HD11 . ILE A 1 2   ? 197.740 146.972 188.264 1.00 149.11 ? 15   ILE A HD11 1 
ATOM   36   H HD12 . ILE A 1 2   ? 197.097 145.436 187.631 1.00 149.64 ? 15   ILE A HD12 1 
ATOM   37   H HD13 . ILE A 1 2   ? 198.556 146.149 186.924 1.00 149.56 ? 15   ILE A HD13 1 
ATOM   38   N N    . GLY A 1 3   ? 196.905 145.578 193.090 1.00 156.67 ? 16   GLY A N    1 
ATOM   39   C CA   . GLY A 1 3   ? 196.988 145.185 194.508 1.00 157.66 ? 16   GLY A CA   1 
ATOM   40   C C    . GLY A 1 3   ? 197.307 146.330 195.476 1.00 158.08 ? 16   GLY A C    1 
ATOM   41   O O    . GLY A 1 3   ? 197.096 147.501 195.167 1.00 162.07 ? 16   GLY A O    1 
ATOM   42   H H    . GLY A 1 3   ? 196.077 145.356 192.557 1.00 157.03 ? 16   GLY A H    1 
ATOM   43   H HA2  . GLY A 1 3   ? 196.043 144.738 194.818 1.00 157.61 ? 16   GLY A HA2  1 
ATOM   44   H HA3  . GLY A 1 3   ? 197.765 144.427 194.609 1.00 157.25 ? 16   GLY A HA3  1 
ATOM   45   N N    . ASP A 1 4   ? 197.839 145.992 196.651 1.00 158.32 ? 17   ASP A N    1 
ATOM   46   C CA   . ASP A 1 4   ? 198.611 146.932 197.479 1.00 157.49 ? 17   ASP A CA   1 
ATOM   47   C C    . ASP A 1 4   ? 199.601 146.262 198.454 1.00 158.54 ? 17   ASP A C    1 
ATOM   48   O O    . ASP A 1 4   ? 200.238 146.952 199.248 1.00 160.00 ? 17   ASP A O    1 
ATOM   49   C CB   . ASP A 1 4   ? 197.700 147.925 198.222 1.00 159.86 ? 17   ASP A CB   1 
ATOM   50   C CG   . ASP A 1 4   ? 196.814 147.322 199.312 1.00 163.36 ? 17   ASP A CG   1 
ATOM   51   O OD1  . ASP A 1 4   ? 196.876 146.102 199.582 1.00 164.71 ? 17   ASP A OD1  1 
ATOM   52   O OD2  . ASP A 1 4   ? 196.053 148.097 199.931 1.00 163.40 ? 17   ASP A OD2  1 
ATOM   53   H H    . ASP A 1 4   ? 197.854 145.012 196.895 1.00 159.55 ? 17   ASP A H    1 
ATOM   54   H HA   . ASP A 1 4   ? 199.224 147.525 196.801 1.00 158.98 ? 17   ASP A HA   1 
ATOM   55   H HB2  . ASP A 1 4   ? 198.331 148.690 198.675 1.00 159.67 ? 17   ASP A HB2  1 
ATOM   56   H HB3  . ASP A 1 4   ? 197.063 148.442 197.505 1.00 159.90 ? 17   ASP A HB3  1 
ATOM   57   N N    . PHE A 1 5   ? 199.773 144.938 198.419 1.00 157.67 ? 18   PHE A N    1 
ATOM   58   C CA   . PHE A 1 5   ? 200.681 144.251 199.333 1.00 155.49 ? 18   PHE A CA   1 
ATOM   59   C C    . PHE A 1 5   ? 202.142 144.293 198.858 1.00 160.44 ? 18   PHE A C    1 
ATOM   60   O O    . PHE A 1 5   ? 202.442 143.941 197.716 1.00 168.53 ? 18   PHE A O    1 
ATOM   61   C CB   . PHE A 1 5   ? 200.186 142.821 199.527 1.00 153.80 ? 18   PHE A CB   1 
ATOM   62   C CG   . PHE A 1 5   ? 200.889 142.116 200.664 1.00 156.08 ? 18   PHE A CG   1 
ATOM   63   C CD1  . PHE A 1 5   ? 202.140 141.515 200.457 1.00 157.40 ? 18   PHE A CD1  1 
ATOM   64   C CD2  . PHE A 1 5   ? 200.307 142.092 201.940 1.00 158.18 ? 18   PHE A CD2  1 
ATOM   65   C CE1  . PHE A 1 5   ? 202.813 140.901 201.524 1.00 158.38 ? 18   PHE A CE1  1 
ATOM   66   C CE2  . PHE A 1 5   ? 200.971 141.465 203.005 1.00 161.30 ? 18   PHE A CE2  1 
ATOM   67   C CZ   . PHE A 1 5   ? 202.231 140.881 202.800 1.00 160.55 ? 18   PHE A CZ   1 
ATOM   68   H H    . PHE A 1 5   ? 199.267 144.380 197.747 1.00 159.89 ? 18   PHE A H    1 
ATOM   69   H HA   . PHE A 1 5   ? 200.631 144.741 200.306 1.00 159.33 ? 18   PHE A HA   1 
ATOM   70   H HB2  . PHE A 1 5   ? 199.118 142.850 199.742 1.00 159.20 ? 18   PHE A HB2  1 
ATOM   71   H HB3  . PHE A 1 5   ? 200.329 142.254 198.608 1.00 159.35 ? 18   PHE A HB3  1 
ATOM   72   H HD1  . PHE A 1 5   ? 202.593 141.533 199.477 1.00 159.86 ? 18   PHE A HD1  1 
ATOM   73   H HD2  . PHE A 1 5   ? 199.342 142.550 202.103 1.00 159.46 ? 18   PHE A HD2  1 
ATOM   74   H HE1  . PHE A 1 5   ? 203.777 140.442 201.361 1.00 159.50 ? 18   PHE A HE1  1 
ATOM   75   H HE2  . PHE A 1 5   ? 200.507 141.423 203.979 1.00 160.29 ? 18   PHE A HE2  1 
ATOM   76   H HZ   . PHE A 1 5   ? 202.745 140.399 203.619 1.00 159.90 ? 18   PHE A HZ   1 
ATOM   77   N N    . ASN A 1 6   ? 203.071 144.678 199.734 1.00 161.52 ? 19   ASN A N    1 
ATOM   78   C CA   . ASN A 1 6   ? 204.505 144.741 199.440 1.00 164.23 ? 19   ASN A CA   1 
ATOM   79   C C    . ASN A 1 6   ? 205.165 143.348 199.467 1.00 168.36 ? 19   ASN A C    1 
ATOM   80   O O    . ASN A 1 6   ? 205.687 142.910 200.491 1.00 165.64 ? 19   ASN A O    1 
ATOM   81   C CB   . ASN A 1 6   ? 205.145 145.709 200.443 1.00 163.47 ? 19   ASN A CB   1 
ATOM   82   C CG   . ASN A 1 6   ? 206.643 145.896 200.244 1.00 170.69 ? 19   ASN A CG   1 
ATOM   83   O OD1  . ASN A 1 6   ? 207.278 145.325 199.364 1.00 175.10 ? 19   ASN A OD1  1 
ATOM   84   N ND2  . ASN A 1 6   ? 207.181 146.727 201.117 1.00 172.52 ? 19   ASN A ND2  1 
ATOM   85   H H    . ASN A 1 6   ? 202.769 144.946 200.659 1.00 166.40 ? 19   ASN A H    1 
ATOM   86   H HA   . ASN A 1 6   ? 204.645 145.155 198.441 1.00 167.47 ? 19   ASN A HA   1 
ATOM   87   H HB2  . ASN A 1 6   ? 204.666 146.683 200.345 1.00 166.93 ? 19   ASN A HB2  1 
ATOM   88   H HB3  . ASN A 1 6   ? 204.977 145.345 201.456 1.00 167.04 ? 19   ASN A HB3  1 
ATOM   89   H HD21 . ASN A 1 6   ? 206.559 147.247 201.720 1.00 168.33 ? 19   ASN A HD21 1 
ATOM   90   N N    . CYS A 1 7   ? 205.096 142.618 198.355 1.00 181.74 ? 20   CYS A N    1 
ATOM   91   C CA   . CYS A 1 7   ? 205.657 141.270 198.239 1.00 179.62 ? 20   CYS A CA   1 
ATOM   92   C C    . CYS A 1 7   ? 207.193 141.237 198.190 1.00 177.48 ? 20   CYS A C    1 
ATOM   93   O O    . CYS A 1 7   ? 207.814 140.365 198.796 1.00 177.89 ? 20   CYS A O    1 
ATOM   94   C CB   . CYS A 1 7   ? 205.070 140.612 196.985 1.00 181.94 ? 20   CYS A CB   1 
ATOM   95   S SG   . CYS A 1 7   ? 203.289 140.314 197.111 1.00 202.62 ? 20   CYS A SG   1 
ATOM   96   H H    . CYS A 1 7   ? 204.551 142.981 197.585 1.00 181.02 ? 20   CYS A H    1 
ATOM   97   H HA   . CYS A 1 7   ? 205.347 140.681 199.103 1.00 180.74 ? 20   CYS A HA   1 
ATOM   98   H HB2  . CYS A 1 7   ? 205.268 141.242 196.119 1.00 181.21 ? 20   CYS A HB2  1 
ATOM   99   H HB3  . CYS A 1 7   ? 205.563 139.653 196.825 1.00 181.28 ? 20   CYS A HB3  1 
ATOM   100  N N    . THR A 1 8   ? 207.824 142.197 197.506 1.00 172.30 ? 21   THR A N    1 
ATOM   101  C CA   . THR A 1 8   ? 209.278 142.407 197.569 1.00 176.82 ? 21   THR A CA   1 
ATOM   102  C C    . THR A 1 8   ? 209.684 143.824 197.158 1.00 174.64 ? 21   THR A C    1 
ATOM   103  O O    . THR A 1 8   ? 209.003 144.471 196.365 1.00 171.40 ? 21   THR A O    1 
ATOM   104  C CB   . THR A 1 8   ? 210.025 141.371 196.712 1.00 179.37 ? 21   THR A CB   1 
ATOM   105  O OG1  . THR A 1 8   ? 211.409 141.463 196.962 1.00 180.33 ? 21   THR A OG1  1 
ATOM   106  C CG2  . THR A 1 8   ? 209.835 141.547 195.206 1.00 176.52 ? 21   THR A CG2  1 
ATOM   107  H H    . THR A 1 8   ? 207.271 142.899 197.037 1.00 175.23 ? 21   THR A H    1 
ATOM   108  H HA   . THR A 1 8   ? 209.588 142.265 198.604 1.00 175.76 ? 21   THR A HA   1 
ATOM   109  H HB   . THR A 1 8   ? 209.691 140.370 196.983 1.00 175.94 ? 21   THR A HB   1 
ATOM   110  H HG1  . THR A 1 8   ? 211.616 140.808 197.629 1.00 175.83 ? 21   THR A HG1  1 
ATOM   111  H HG21 . THR A 1 8   ? 210.335 140.731 194.688 1.00 175.59 ? 21   THR A HG21 1 
ATOM   112  H HG22 . THR A 1 8   ? 208.775 141.518 194.962 1.00 175.69 ? 21   THR A HG22 1 
ATOM   113  H HG23 . THR A 1 8   ? 210.258 142.491 194.870 1.00 175.82 ? 21   THR A HG23 1 
ATOM   114  N N    . ASN A 1 9   ? 210.845 144.275 197.634 1.00 176.83 ? 22   ASN A N    1 
ATOM   115  C CA   . ASN A 1 9   ? 211.530 145.474 197.152 1.00 177.83 ? 22   ASN A CA   1 
ATOM   116  C C    . ASN A 1 9   ? 212.568 145.168 196.048 1.00 182.21 ? 22   ASN A C    1 
ATOM   117  O O    . ASN A 1 9   ? 213.149 146.090 195.482 1.00 181.14 ? 22   ASN A O    1 
ATOM   118  C CB   . ASN A 1 9   ? 212.198 146.160 198.354 1.00 177.17 ? 22   ASN A CB   1 
ATOM   119  C CG   . ASN A 1 9   ? 213.335 145.340 198.938 1.00 179.83 ? 22   ASN A CG   1 
ATOM   120  O OD1  . ASN A 1 9   ? 214.466 145.402 198.489 1.00 180.44 ? 22   ASN A OD1  1 
ATOM   121  N ND2  . ASN A 1 9   ? 213.082 144.518 199.928 1.00 178.55 ? 22   ASN A ND2  1 
ATOM   122  H H    . ASN A 1 9   ? 211.352 143.671 198.265 1.00 178.28 ? 22   ASN A H    1 
ATOM   123  H HA   . ASN A 1 9   ? 210.800 146.165 196.733 1.00 178.05 ? 22   ASN A HA   1 
ATOM   124  H HB2  . ASN A 1 9   ? 212.606 147.117 198.033 1.00 177.96 ? 22   ASN A HB2  1 
ATOM   125  H HB3  . ASN A 1 9   ? 211.454 146.364 199.123 1.00 178.08 ? 22   ASN A HB3  1 
ATOM   126  H HD21 . ASN A 1 9   ? 212.163 144.460 200.337 1.00 178.38 ? 22   ASN A HD21 1 
ATOM   127  H HD22 . ASN A 1 9   ? 213.855 143.989 200.301 1.00 178.54 ? 22   ASN A HD22 1 
ATOM   128  N N    . PHE A 1 10  ? 212.853 143.892 195.776 1.00 180.15 ? 23   PHE A N    1 
ATOM   129  C CA   . PHE A 1 10  ? 214.016 143.488 194.986 1.00 176.22 ? 23   PHE A CA   1 
ATOM   130  C C    . PHE A 1 10  ? 213.951 143.956 193.525 1.00 174.26 ? 23   PHE A C    1 
ATOM   131  O O    . PHE A 1 10  ? 213.028 143.601 192.793 1.00 172.26 ? 23   PHE A O    1 
ATOM   132  C CB   . PHE A 1 10  ? 214.173 141.966 195.065 1.00 172.09 ? 23   PHE A CB   1 
ATOM   133  C CG   . PHE A 1 10  ? 215.276 141.423 194.182 1.00 174.12 ? 23   PHE A CG   1 
ATOM   134  C CD1  . PHE A 1 10  ? 216.617 141.706 194.489 1.00 174.60 ? 23   PHE A CD1  1 
ATOM   135  C CD2  . PHE A 1 10  ? 214.971 140.650 193.048 1.00 173.49 ? 23   PHE A CD2  1 
ATOM   136  C CE1  . PHE A 1 10  ? 217.646 141.231 193.662 1.00 174.94 ? 23   PHE A CE1  1 
ATOM   137  C CE2  . PHE A 1 10  ? 216.001 140.163 192.226 1.00 172.88 ? 23   PHE A CE2  1 
ATOM   138  C CZ   . PHE A 1 10  ? 217.338 140.460 192.531 1.00 175.37 ? 23   PHE A CZ   1 
ATOM   139  H H    . PHE A 1 10  ? 212.326 143.161 196.229 1.00 175.15 ? 23   PHE A H    1 
ATOM   140  H HA   . PHE A 1 10  ? 214.900 143.931 195.442 1.00 174.56 ? 23   PHE A HA   1 
ATOM   141  H HB2  . PHE A 1 10  ? 214.383 141.683 196.095 1.00 173.88 ? 23   PHE A HB2  1 
ATOM   142  H HB3  . PHE A 1 10  ? 213.232 141.500 194.777 1.00 173.96 ? 23   PHE A HB3  1 
ATOM   143  H HD1  . PHE A 1 10  ? 216.857 142.293 195.363 1.00 174.15 ? 23   PHE A HD1  1 
ATOM   144  H HD2  . PHE A 1 10  ? 213.943 140.428 192.806 1.00 174.19 ? 23   PHE A HD2  1 
ATOM   145  H HE1  . PHE A 1 10  ? 218.676 141.454 193.896 1.00 174.25 ? 23   PHE A HE1  1 
ATOM   146  H HE2  . PHE A 1 10  ? 215.770 139.568 191.356 1.00 174.02 ? 23   PHE A HE2  1 
ATOM   147  H HZ   . PHE A 1 10  ? 218.130 140.095 191.895 1.00 174.74 ? 23   PHE A HZ   1 
ATOM   148  N N    . ALA A 1 11  ? 214.979 144.690 193.097 1.00 172.21 ? 24   ALA A N    1 
ATOM   149  C CA   . ALA A 1 11  ? 215.241 145.075 191.711 1.00 175.40 ? 24   ALA A CA   1 
ATOM   150  C C    . ALA A 1 11  ? 214.024 145.685 190.986 1.00 177.96 ? 24   ALA A C    1 
ATOM   151  O O    . ALA A 1 11  ? 213.514 145.140 190.007 1.00 181.35 ? 24   ALA A O    1 
ATOM   152  C CB   . ALA A 1 11  ? 215.903 143.896 190.987 1.00 176.80 ? 24   ALA A CB   1 
ATOM   153  H H    . ALA A 1 11  ? 215.681 144.937 193.779 1.00 174.81 ? 24   ALA A H    1 
ATOM   154  H HA   . ALA A 1 11  ? 215.983 145.872 191.740 1.00 175.08 ? 24   ALA A HA   1 
ATOM   155  H HB1  . ALA A 1 11  ? 215.239 143.033 190.979 1.00 175.40 ? 24   ALA A HB1  1 
ATOM   156  H HB2  . ALA A 1 11  ? 216.825 143.623 191.496 1.00 175.33 ? 24   ALA A HB2  1 
ATOM   157  H HB3  . ALA A 1 11  ? 216.139 144.174 189.962 1.00 175.75 ? 24   ALA A HB3  1 
ATOM   158  N N    . ILE A 1 12  ? 213.563 146.841 191.455 1.00 169.69 ? 25   ILE A N    1 
ATOM   159  C CA   . ILE A 1 12  ? 212.501 147.636 190.822 1.00 169.33 ? 25   ILE A CA   1 
ATOM   160  C C    . ILE A 1 12  ? 213.062 149.000 190.429 1.00 166.55 ? 25   ILE A C    1 
ATOM   161  O O    . ILE A 1 12  ? 213.857 149.582 191.166 1.00 168.69 ? 25   ILE A O    1 
ATOM   162  C CB   . ILE A 1 12  ? 211.290 147.737 191.766 1.00 167.79 ? 25   ILE A CB   1 
ATOM   163  C CG1  . ILE A 1 12  ? 210.560 146.381 191.827 1.00 166.61 ? 25   ILE A CG1  1 
ATOM   164  C CG2  . ILE A 1 12  ? 210.290 148.820 191.332 1.00 165.03 ? 25   ILE A CG2  1 
ATOM   165  C CD1  . ILE A 1 12  ? 209.829 146.176 193.153 1.00 168.87 ? 25   ILE A CD1  1 
ATOM   166  H H    . ILE A 1 12  ? 214.018 147.241 192.262 1.00 167.41 ? 25   ILE A H    1 
ATOM   167  H HA   . ILE A 1 12  ? 212.169 147.150 189.905 1.00 167.61 ? 25   ILE A HA   1 
ATOM   168  H HB   . ILE A 1 12  ? 211.656 147.995 192.759 1.00 167.26 ? 25   ILE A HB   1 
ATOM   169  H HG12 . ILE A 1 12  ? 209.846 146.303 191.008 1.00 166.99 ? 25   ILE A HG12 1 
ATOM   170  H HG13 . ILE A 1 12  ? 211.270 145.562 191.723 1.00 166.99 ? 25   ILE A HG13 1 
ATOM   171  H HG21 . ILE A 1 12  ? 209.413 148.804 191.977 1.00 166.78 ? 25   ILE A HG21 1 
ATOM   172  H HG22 . ILE A 1 12  ? 209.973 148.651 190.305 1.00 166.91 ? 25   ILE A HG22 1 
ATOM   173  H HG23 . ILE A 1 12  ? 210.739 149.808 191.417 1.00 166.66 ? 25   ILE A HG23 1 
ATOM   174  H HD11 . ILE A 1 12  ? 209.116 146.979 193.320 1.00 167.49 ? 25   ILE A HD11 1 
ATOM   175  H HD12 . ILE A 1 12  ? 210.546 146.160 193.970 1.00 167.58 ? 25   ILE A HD12 1 
ATOM   176  H HD13 . ILE A 1 12  ? 209.300 145.226 193.131 1.00 167.54 ? 25   ILE A HD13 1 
ATOM   177  N N    . ASN A 1 13  ? 212.655 149.527 189.274 1.00 163.76 ? 26   ASN A N    1 
ATOM   178  C CA   . ASN A 1 13  ? 213.069 150.842 188.783 1.00 166.50 ? 26   ASN A CA   1 
ATOM   179  C C    . ASN A 1 13  ? 211.936 151.518 187.997 1.00 169.84 ? 26   ASN A C    1 
ATOM   180  O O    . ASN A 1 13  ? 210.840 150.982 187.890 1.00 170.61 ? 26   ASN A O    1 
ATOM   181  C CB   . ASN A 1 13  ? 214.373 150.700 187.974 1.00 167.33 ? 26   ASN A CB   1 
ATOM   182  C CG   . ASN A 1 13  ? 214.230 149.916 186.685 1.00 168.73 ? 26   ASN A CG   1 
ATOM   183  O OD1  . ASN A 1 13  ? 213.250 150.014 185.968 1.00 169.45 ? 26   ASN A OD1  1 
ATOM   184  N ND2  . ASN A 1 13  ? 215.222 149.137 186.327 1.00 170.02 ? 26   ASN A ND2  1 
ATOM   185  H H    . ASN A 1 13  ? 211.964 149.027 188.734 1.00 167.94 ? 26   ASN A H    1 
ATOM   186  H HA   . ASN A 1 13  ? 213.275 151.489 189.635 1.00 167.98 ? 26   ASN A HA   1 
ATOM   187  H HB2  . ASN A 1 13  ? 214.763 151.685 187.721 1.00 168.33 ? 26   ASN A HB2  1 
ATOM   188  H HB3  . ASN A 1 13  ? 215.119 150.215 188.602 1.00 167.89 ? 26   ASN A HB3  1 
ATOM   189  H HD21 . ASN A 1 13  ? 216.051 149.066 186.897 1.00 168.34 ? 26   ASN A HD21 1 
ATOM   190  H HD22 . ASN A 1 13  ? 215.141 148.637 185.454 1.00 168.66 ? 26   ASN A HD22 1 
ATOM   191  N N    . ASP A 1 14  ? 212.189 152.702 187.437 1.00 177.46 ? 27   ASP A N    1 
ATOM   192  C CA   . ASP A 1 14  ? 211.194 153.475 186.684 1.00 176.14 ? 27   ASP A CA   1 
ATOM   193  C C    . ASP A 1 14  ? 211.490 153.513 185.171 1.00 175.85 ? 27   ASP A C    1 
ATOM   194  O O    . ASP A 1 14  ? 211.232 154.515 184.504 1.00 176.13 ? 27   ASP A O    1 
ATOM   195  C CB   . ASP A 1 14  ? 211.058 154.873 187.305 1.00 176.69 ? 27   ASP A CB   1 
ATOM   196  C CG   . ASP A 1 14  ? 210.682 154.853 188.791 1.00 180.30 ? 27   ASP A CG   1 
ATOM   197  O OD1  . ASP A 1 14  ? 209.978 153.923 189.238 1.00 182.77 ? 27   ASP A OD1  1 
ATOM   198  O OD2  . ASP A 1 14  ? 211.068 155.807 189.505 1.00 181.78 ? 27   ASP A OD2  1 
ATOM   199  H H    . ASP A 1 14  ? 213.106 153.103 187.564 1.00 176.86 ? 27   ASP A H    1 
ATOM   200  H HA   . ASP A 1 14  ? 210.220 152.996 186.776 1.00 176.81 ? 27   ASP A HA   1 
ATOM   201  H HB2  . ASP A 1 14  ? 212.001 155.400 187.179 1.00 176.85 ? 27   ASP A HB2  1 
ATOM   202  H HB3  . ASP A 1 14  ? 210.288 155.423 186.768 1.00 176.83 ? 27   ASP A HB3  1 
ATOM   203  N N    . LEU A 1 15  ? 212.081 152.452 184.611 1.00 179.20 ? 28   LEU A N    1 
ATOM   204  C CA   . LEU A 1 15  ? 212.475 152.411 183.199 1.00 180.01 ? 28   LEU A CA   1 
ATOM   205  C C    . LEU A 1 15  ? 211.267 152.586 182.262 1.00 180.51 ? 28   LEU A C    1 
ATOM   206  O O    . LEU A 1 15  ? 210.261 151.893 182.395 1.00 181.14 ? 28   LEU A O    1 
ATOM   207  C CB   . LEU A 1 15  ? 213.232 151.100 182.933 1.00 181.56 ? 28   LEU A CB   1 
ATOM   208  C CG   . LEU A 1 15  ? 213.719 150.913 181.487 1.00 183.94 ? 28   LEU A CG   1 
ATOM   209  C CD1  . LEU A 1 15  ? 214.763 151.956 181.093 1.00 182.43 ? 28   LEU A CD1  1 
ATOM   210  C CD2  . LEU A 1 15  ? 214.350 149.532 181.333 1.00 183.51 ? 28   LEU A CD2  1 
ATOM   211  H H    . LEU A 1 15  ? 212.296 151.652 185.188 1.00 180.57 ? 28   LEU A H    1 
ATOM   212  H HA   . LEU A 1 15  ? 213.161 153.241 183.028 1.00 180.69 ? 28   LEU A HA   1 
ATOM   213  H HB2  . LEU A 1 15  ? 214.093 151.052 183.598 1.00 180.96 ? 28   LEU A HB2  1 
ATOM   214  H HB3  . LEU A 1 15  ? 212.573 150.268 183.180 1.00 181.16 ? 28   LEU A HB3  1 
ATOM   215  H HG   . LEU A 1 15  ? 212.873 150.977 180.804 1.00 181.33 ? 28   LEU A HG   1 
ATOM   216  H HD11 . LEU A 1 15  ? 215.607 151.916 181.777 1.00 180.95 ? 28   LEU A HD11 1 
ATOM   217  H HD12 . LEU A 1 15  ? 214.332 152.955 181.111 1.00 181.01 ? 28   LEU A HD12 1 
ATOM   218  H HD13 . LEU A 1 15  ? 215.119 151.755 180.085 1.00 181.51 ? 28   LEU A HD13 1 
ATOM   219  H HD21 . LEU A 1 15  ? 214.673 149.389 180.303 1.00 181.29 ? 28   LEU A HD21 1 
ATOM   220  H HD22 . LEU A 1 15  ? 215.208 149.435 181.997 1.00 181.37 ? 28   LEU A HD22 1 
ATOM   221  H HD23 . LEU A 1 15  ? 213.619 148.765 181.581 1.00 181.27 ? 28   LEU A HD23 1 
ATOM   222  N N    . ASN A 1 16  ? 211.372 153.505 181.305 1.00 191.58 ? 29   ASN A N    1 
ATOM   223  C CA   . ASN A 1 16  ? 210.255 153.965 180.475 1.00 192.57 ? 29   ASN A CA   1 
ATOM   224  C C    . ASN A 1 16  ? 210.202 153.334 179.069 1.00 193.43 ? 29   ASN A C    1 
ATOM   225  O O    . ASN A 1 16  ? 209.275 153.587 178.306 1.00 193.25 ? 29   ASN A O    1 
ATOM   226  C CB   . ASN A 1 16  ? 210.394 155.494 180.400 1.00 193.52 ? 29   ASN A CB   1 
ATOM   227  C CG   . ASN A 1 16  ? 209.151 156.205 179.897 1.00 196.78 ? 29   ASN A CG   1 
ATOM   228  O OD1  . ASN A 1 16  ? 208.031 155.743 180.082 1.00 197.35 ? 29   ASN A OD1  1 
ATOM   229  N ND2  . ASN A 1 16  ? 209.361 157.398 179.367 1.00 199.71 ? 29   ASN A ND2  1 
ATOM   230  H H    . ASN A 1 16  ? 212.215 154.057 181.282 1.00 193.57 ? 29   ASN A H    1 
ATOM   231  H HA   . ASN A 1 16  ? 209.315 153.720 180.969 1.00 194.04 ? 29   ASN A HA   1 
ATOM   232  H HB2  . ASN A 1 16  ? 210.601 155.889 181.393 1.00 194.00 ? 29   ASN A HB2  1 
ATOM   233  H HB3  . ASN A 1 16  ? 211.239 155.741 179.759 1.00 193.86 ? 29   ASN A HB3  1 
ATOM   234  H HD21 . ASN A 1 16  ? 210.314 157.715 179.279 1.00 194.56 ? 29   ASN A HD21 1 
ATOM   235  N N    . THR A 1 17  ? 211.252 152.629 178.648 1.00 198.29 ? 30   THR A N    1 
ATOM   236  C CA   . THR A 1 17  ? 211.518 152.272 177.240 1.00 200.43 ? 30   THR A CA   1 
ATOM   237  C C    . THR A 1 17  ? 210.734 151.045 176.743 1.00 199.13 ? 30   THR A C    1 
ATOM   238  O O    . THR A 1 17  ? 211.301 150.134 176.140 1.00 200.03 ? 30   THR A O    1 
ATOM   239  C CB   . THR A 1 17  ? 213.028 152.130 176.989 1.00 200.22 ? 30   THR A CB   1 
ATOM   240  O OG1  . THR A 1 17  ? 213.561 151.075 177.754 1.00 201.55 ? 30   THR A OG1  1 
ATOM   241  C CG2  . THR A 1 17  ? 213.800 153.400 177.343 1.00 197.08 ? 30   THR A CG2  1 
ATOM   242  H H    . THR A 1 17  ? 211.984 152.433 179.315 1.00 197.35 ? 30   THR A H    1 
ATOM   243  H HA   . THR A 1 17  ? 211.183 153.102 176.620 1.00 197.80 ? 30   THR A HA   1 
ATOM   244  H HB   . THR A 1 17  ? 213.195 151.923 175.933 1.00 197.92 ? 30   THR A HB   1 
ATOM   245  H HG1  . THR A 1 17  ? 213.201 150.268 177.386 1.00 197.92 ? 30   THR A HG1  1 
ATOM   246  H HG21 . THR A 1 17  ? 213.749 153.601 178.411 1.00 197.40 ? 30   THR A HG21 1 
ATOM   247  H HG22 . THR A 1 17  ? 214.842 153.279 177.058 1.00 197.57 ? 30   THR A HG22 1 
ATOM   248  H HG23 . THR A 1 17  ? 213.386 154.243 176.795 1.00 197.33 ? 30   THR A HG23 1 
ATOM   249  N N    . THR A 1 18  ? 209.431 151.001 176.996 1.00 173.33 ? 31   THR A N    1 
ATOM   250  C CA   . THR A 1 18  ? 208.515 149.954 176.508 1.00 172.67 ? 31   THR A CA   1 
ATOM   251  C C    . THR A 1 18  ? 207.230 150.563 175.971 1.00 175.78 ? 31   THR A C    1 
ATOM   252  O O    . THR A 1 18  ? 206.632 151.410 176.631 1.00 174.11 ? 31   THR A O    1 
ATOM   253  C CB   . THR A 1 18  ? 208.170 148.938 177.605 1.00 171.00 ? 31   THR A CB   1 
ATOM   254  O OG1  . THR A 1 18  ? 207.731 149.579 178.782 1.00 171.80 ? 31   THR A OG1  1 
ATOM   255  C CG2  . THR A 1 18  ? 209.358 148.056 177.974 1.00 169.89 ? 31   THR A CG2  1 
ATOM   256  H H    . THR A 1 18  ? 209.023 151.782 177.488 1.00 172.08 ? 31   THR A H    1 
ATOM   257  H HA   . THR A 1 18  ? 208.988 149.411 175.690 1.00 171.60 ? 31   THR A HA   1 
ATOM   258  H HB   . THR A 1 18  ? 207.375 148.289 177.241 1.00 171.03 ? 31   THR A HB   1 
ATOM   259  H HG1  . THR A 1 18  ? 207.087 150.239 178.523 1.00 171.38 ? 31   THR A HG1  1 
ATOM   260  H HG21 . THR A 1 18  ? 209.763 147.589 177.079 1.00 171.18 ? 31   THR A HG21 1 
ATOM   261  H HG22 . THR A 1 18  ? 209.030 147.271 178.654 1.00 171.11 ? 31   THR A HG22 1 
ATOM   262  H HG23 . THR A 1 18  ? 210.137 148.648 178.451 1.00 171.71 ? 31   THR A HG23 1 
ATOM   263  N N    . VAL A 1 19  ? 206.770 150.105 174.806 1.00 161.72 ? 32   VAL A N    1 
ATOM   264  C CA   . VAL A 1 19  ? 205.571 150.625 174.124 1.00 157.66 ? 32   VAL A CA   1 
ATOM   265  C C    . VAL A 1 19  ? 204.642 149.506 173.673 1.00 152.05 ? 32   VAL A C    1 
ATOM   266  O O    . VAL A 1 19  ? 205.086 148.410 173.333 1.00 151.11 ? 32   VAL A O    1 
ATOM   267  C CB   . VAL A 1 19  ? 205.925 151.527 172.928 1.00 148.05 ? 32   VAL A CB   1 
ATOM   268  C CG1  . VAL A 1 19  ? 206.668 152.781 173.382 1.00 148.95 ? 32   VAL A CG1  1 
ATOM   269  C CG2  . VAL A 1 19  ? 206.755 150.824 171.855 1.00 146.96 ? 32   VAL A CG2  1 
ATOM   270  H H    . VAL A 1 19  ? 207.284 149.374 174.337 1.00 152.84 ? 32   VAL A H    1 
ATOM   271  H HA   . VAL A 1 19  ? 205.004 151.239 174.822 1.00 153.14 ? 32   VAL A HA   1 
ATOM   272  H HB   . VAL A 1 19  ? 204.996 151.854 172.469 1.00 150.75 ? 32   VAL A HB   1 
ATOM   273  H HG11 . VAL A 1 19  ? 206.093 153.286 174.151 1.00 151.31 ? 32   VAL A HG11 1 
ATOM   274  H HG12 . VAL A 1 19  ? 207.644 152.523 173.777 1.00 152.14 ? 32   VAL A HG12 1 
ATOM   275  H HG13 . VAL A 1 19  ? 206.796 153.459 172.541 1.00 151.58 ? 32   VAL A HG13 1 
ATOM   276  H HG21 . VAL A 1 19  ? 206.951 151.512 171.036 1.00 151.60 ? 32   VAL A HG21 1 
ATOM   277  H HG22 . VAL A 1 19  ? 207.701 150.490 172.263 1.00 151.45 ? 32   VAL A HG22 1 
ATOM   278  H HG23 . VAL A 1 19  ? 206.210 149.975 171.459 1.00 150.84 ? 32   VAL A HG23 1 
ATOM   279  N N    . ILE A 1 20  ? 203.337 149.780 173.660 1.00 145.16 ? 35   ILE A N    1 
ATOM   280  C CA   . ILE A 1 20  ? 202.327 148.828 173.208 1.00 146.91 ? 35   ILE A CA   1 
ATOM   281  C C    . ILE A 1 20  ? 202.457 148.635 171.699 1.00 145.74 ? 35   ILE A C    1 
ATOM   282  O O    . ILE A 1 20  ? 202.344 149.592 170.937 1.00 143.91 ? 35   ILE A O    1 
ATOM   283  C CB   . ILE A 1 20  ? 200.915 149.327 173.568 1.00 146.11 ? 35   ILE A CB   1 
ATOM   284  C CG1  . ILE A 1 20  ? 200.742 149.708 175.050 1.00 141.79 ? 35   ILE A CG1  1 
ATOM   285  C CG2  . ILE A 1 20  ? 199.870 148.277 173.179 1.00 145.35 ? 35   ILE A CG2  1 
ATOM   286  C CD1  . ILE A 1 20  ? 201.042 148.582 176.035 1.00 142.23 ? 35   ILE A CD1  1 
ATOM   287  H H    . ILE A 1 20  ? 203.037 150.705 173.927 1.00 144.45 ? 35   ILE A H    1 
ATOM   288  H HA   . ILE A 1 20  ? 202.491 147.871 173.701 1.00 144.11 ? 35   ILE A HA   1 
ATOM   289  H HB   . ILE A 1 20  ? 200.709 150.225 172.988 1.00 144.09 ? 35   ILE A HB   1 
ATOM   290  H HG12 . ILE A 1 20  ? 201.392 150.550 175.283 1.00 143.92 ? 35   ILE A HG12 1 
ATOM   291  H HG13 . ILE A 1 20  ? 199.719 150.045 175.214 1.00 143.37 ? 35   ILE A HG13 1 
ATOM   292  H HG21 . ILE A 1 20  ? 198.899 148.575 173.569 1.00 143.75 ? 35   ILE A HG21 1 
ATOM   293  H HG22 . ILE A 1 20  ? 199.795 148.206 172.095 1.00 144.54 ? 35   ILE A HG22 1 
ATOM   294  H HG23 . ILE A 1 20  ? 200.135 147.301 173.582 1.00 143.35 ? 35   ILE A HG23 1 
ATOM   295  H HD11 . ILE A 1 20  ? 200.864 148.944 177.046 1.00 144.11 ? 35   ILE A HD11 1 
ATOM   296  H HD12 . ILE A 1 20  ? 202.082 148.276 175.946 1.00 143.90 ? 35   ILE A HD12 1 
ATOM   297  H HD13 . ILE A 1 20  ? 200.395 147.726 175.854 1.00 143.16 ? 35   ILE A HD13 1 
ATOM   298  N N    . SER A 1 21  ? 202.685 147.406 171.249 1.00 140.35 ? 36   SER A N    1 
ATOM   299  C CA   . SER A 1 21  ? 202.595 147.058 169.832 1.00 137.40 ? 36   SER A CA   1 
ATOM   300  C C    . SER A 1 21  ? 201.134 146.833 169.445 1.00 143.61 ? 36   SER A C    1 
ATOM   301  O O    . SER A 1 21  ? 200.364 146.314 170.250 1.00 150.72 ? 36   SER A O    1 
ATOM   302  C CB   . SER A 1 21  ? 203.448 145.826 169.557 1.00 137.63 ? 36   SER A CB   1 
ATOM   303  O OG   . SER A 1 21  ? 203.492 145.562 168.171 1.00 141.94 ? 36   SER A OG   1 
ATOM   304  H H    . SER A 1 21  ? 202.776 146.658 171.921 1.00 141.45 ? 36   SER A H    1 
ATOM   305  H HA   . SER A 1 21  ? 202.989 147.879 169.233 1.00 140.81 ? 36   SER A HA   1 
ATOM   306  H HB2  . SER A 1 21  ? 204.459 146.010 169.916 1.00 140.85 ? 36   SER A HB2  1 
ATOM   307  H HB3  . SER A 1 21  ? 203.037 144.968 170.085 1.00 141.33 ? 36   SER A HB3  1 
ATOM   308  H HG   . SER A 1 21  ? 204.148 144.881 168.024 1.00 141.39 ? 36   SER A HG   1 
ATOM   309  N N    . GLU A 1 22  ? 200.724 147.214 168.236 1.00 149.61 ? 37   GLU A N    1 
ATOM   310  C CA   . GLU A 1 22  ? 199.326 147.138 167.795 1.00 149.52 ? 37   GLU A CA   1 
ATOM   311  C C    . GLU A 1 22  ? 199.156 146.489 166.417 1.00 147.66 ? 37   GLU A C    1 
ATOM   312  O O    . GLU A 1 22  ? 200.049 146.520 165.573 1.00 150.46 ? 37   GLU A O    1 
ATOM   313  C CB   . GLU A 1 22  ? 198.654 148.514 167.829 1.00 148.42 ? 37   GLU A CB   1 
ATOM   314  C CG   . GLU A 1 22  ? 198.539 149.060 169.255 1.00 152.41 ? 37   GLU A CG   1 
ATOM   315  C CD   . GLU A 1 22  ? 197.766 150.382 169.326 1.00 159.67 ? 37   GLU A CD   1 
ATOM   316  O OE1  . GLU A 1 22  ? 196.823 150.593 168.533 1.00 160.89 ? 37   GLU A OE1  1 
ATOM   317  O OE2  . GLU A 1 22  ? 198.090 151.222 170.192 1.00 161.79 ? 37   GLU A OE2  1 
ATOM   318  H H    . GLU A 1 22  ? 201.406 147.579 167.588 1.00 150.17 ? 37   GLU A H    1 
ATOM   319  H HA   . GLU A 1 22  ? 198.772 146.510 168.492 1.00 150.76 ? 37   GLU A HA   1 
ATOM   320  H HB2  . GLU A 1 22  ? 199.219 149.212 167.213 1.00 150.74 ? 37   GLU A HB2  1 
ATOM   321  H HB3  . GLU A 1 22  ? 197.656 148.415 167.408 1.00 150.05 ? 37   GLU A HB3  1 
ATOM   322  H HG2  . GLU A 1 22  ? 198.028 148.322 169.867 1.00 150.92 ? 37   GLU A HG2  1 
ATOM   323  H HG3  . GLU A 1 22  ? 199.538 149.204 169.657 1.00 150.70 ? 37   GLU A HG3  1 
ATOM   324  N N    . TYR A 1 23  ? 197.992 145.888 166.207 1.00 132.63 ? 38   TYR A N    1 
ATOM   325  C CA   . TYR A 1 23  ? 197.645 145.026 165.075 1.00 132.09 ? 38   TYR A CA   1 
ATOM   326  C C    . TYR A 1 23  ? 196.142 145.130 164.807 1.00 135.70 ? 38   TYR A C    1 
ATOM   327  O O    . TYR A 1 23  ? 195.406 145.520 165.703 1.00 144.20 ? 38   TYR A O    1 
ATOM   328  C CB   . TYR A 1 23  ? 198.084 143.608 165.455 1.00 137.06 ? 38   TYR A CB   1 
ATOM   329  C CG   . TYR A 1 23  ? 197.574 142.475 164.601 1.00 133.98 ? 38   TYR A CG   1 
ATOM   330  C CD1  . TYR A 1 23  ? 197.994 142.360 163.268 1.00 138.53 ? 38   TYR A CD1  1 
ATOM   331  C CD2  . TYR A 1 23  ? 196.740 141.495 165.164 1.00 129.31 ? 38   TYR A CD2  1 
ATOM   332  C CE1  . TYR A 1 23  ? 197.557 141.275 162.487 1.00 142.14 ? 38   TYR A CE1  1 
ATOM   333  C CE2  . TYR A 1 23  ? 196.288 140.417 164.386 1.00 136.63 ? 38   TYR A CE2  1 
ATOM   334  C CZ   . TYR A 1 23  ? 196.691 140.310 163.039 1.00 146.31 ? 38   TYR A CZ   1 
ATOM   335  O OH   . TYR A 1 23  ? 196.253 139.280 162.271 1.00 148.44 ? 38   TYR A OH   1 
ATOM   336  H H    . TYR A 1 23  ? 197.297 145.959 166.935 1.00 137.49 ? 38   TYR A H    1 
ATOM   337  H HA   . TYR A 1 23  ? 198.177 145.339 164.177 1.00 136.33 ? 38   TYR A HA   1 
ATOM   338  H HB2  . TYR A 1 23  ? 199.172 143.573 165.449 1.00 137.74 ? 38   TYR A HB2  1 
ATOM   339  H HB3  . TYR A 1 23  ? 197.767 143.413 166.479 1.00 138.08 ? 38   TYR A HB3  1 
ATOM   340  H HD1  . TYR A 1 23  ? 198.662 143.094 162.845 1.00 136.92 ? 38   TYR A HD1  1 
ATOM   341  H HD2  . TYR A 1 23  ? 196.455 141.557 166.202 1.00 136.37 ? 38   TYR A HD2  1 
ATOM   342  H HE1  . TYR A 1 23  ? 197.874 141.181 161.460 1.00 137.22 ? 38   TYR A HE1  1 
ATOM   343  H HE2  . TYR A 1 23  ? 195.636 139.673 164.816 1.00 136.83 ? 38   TYR A HE2  1 
ATOM   344  H HH   . TYR A 1 23  ? 195.560 138.784 162.699 1.00 138.50 ? 38   TYR A HH   1 
ATOM   345  N N    . VAL A 1 24  ? 195.642 144.823 163.609 1.00 122.97 ? 39   VAL A N    1 
ATOM   346  C CA   . VAL A 1 24  ? 194.251 145.147 163.223 1.00 122.75 ? 39   VAL A CA   1 
ATOM   347  C C    . VAL A 1 24  ? 193.347 143.917 163.219 1.00 127.93 ? 39   VAL A C    1 
ATOM   348  O O    . VAL A 1 24  ? 193.666 142.908 162.600 1.00 128.39 ? 39   VAL A O    1 
ATOM   349  C CB   . VAL A 1 24  ? 194.206 145.860 161.867 1.00 124.58 ? 39   VAL A CB   1 
ATOM   350  C CG1  . VAL A 1 24  ? 192.779 146.242 161.478 1.00 128.14 ? 39   VAL A CG1  1 
ATOM   351  C CG2  . VAL A 1 24  ? 195.034 147.147 161.905 1.00 123.66 ? 39   VAL A CG2  1 
ATOM   352  H H    . VAL A 1 24  ? 196.257 144.436 162.909 1.00 126.59 ? 39   VAL A H    1 
ATOM   353  H HA   . VAL A 1 24  ? 193.833 145.848 163.946 1.00 125.73 ? 39   VAL A HA   1 
ATOM   354  H HB   . VAL A 1 24  ? 194.614 145.203 161.101 1.00 126.49 ? 39   VAL A HB   1 
ATOM   355  H HG11 . VAL A 1 24  ? 192.182 145.349 161.302 1.00 126.23 ? 39   VAL A HG11 1 
ATOM   356  H HG12 . VAL A 1 24  ? 192.790 146.824 160.558 1.00 127.31 ? 39   VAL A HG12 1 
ATOM   357  H HG13 . VAL A 1 24  ? 192.325 146.841 162.265 1.00 126.55 ? 39   VAL A HG13 1 
ATOM   358  H HG21 . VAL A 1 24  ? 196.079 146.917 162.093 1.00 126.80 ? 39   VAL A HG21 1 
ATOM   359  H HG22 . VAL A 1 24  ? 194.663 147.805 162.687 1.00 125.46 ? 39   VAL A HG22 1 
ATOM   360  H HG23 . VAL A 1 24  ? 194.968 147.657 160.947 1.00 126.14 ? 39   VAL A HG23 1 
ATOM   361  N N    . VAL A 1 25  ? 192.202 143.998 163.892 1.00 132.17 ? 40   VAL A N    1 
ATOM   362  C CA   . VAL A 1 25  ? 191.198 142.930 163.972 1.00 128.87 ? 40   VAL A CA   1 
ATOM   363  C C    . VAL A 1 25  ? 190.609 142.671 162.594 1.00 133.93 ? 40   VAL A C    1 
ATOM   364  O O    . VAL A 1 25  ? 190.102 143.586 161.951 1.00 136.73 ? 40   VAL A O    1 
ATOM   365  C CB   . VAL A 1 25  ? 190.078 143.302 164.954 1.00 128.05 ? 40   VAL A CB   1 
ATOM   366  C CG1  . VAL A 1 25  ? 188.974 142.244 165.006 1.00 127.90 ? 40   VAL A CG1  1 
ATOM   367  C CG2  . VAL A 1 25  ? 190.595 143.442 166.384 1.00 130.13 ? 40   VAL A CG2  1 
ATOM   368  H H    . VAL A 1 25  ? 191.996 144.870 164.357 1.00 131.59 ? 40   VAL A H    1 
ATOM   369  H HA   . VAL A 1 25  ? 191.678 142.019 164.327 1.00 130.74 ? 40   VAL A HA   1 
ATOM   370  H HB   . VAL A 1 25  ? 189.635 144.249 164.649 1.00 131.28 ? 40   VAL A HB   1 
ATOM   371  H HG11 . VAL A 1 25  ? 188.221 142.552 165.732 1.00 131.18 ? 40   VAL A HG11 1 
ATOM   372  H HG12 . VAL A 1 25  ? 189.387 141.279 165.299 1.00 130.78 ? 40   VAL A HG12 1 
ATOM   373  H HG13 . VAL A 1 25  ? 188.487 142.152 164.036 1.00 131.41 ? 40   VAL A HG13 1 
ATOM   374  H HG21 . VAL A 1 25  ? 191.454 144.112 166.425 1.00 131.49 ? 40   VAL A HG21 1 
ATOM   375  H HG22 . VAL A 1 25  ? 190.890 142.468 166.776 1.00 131.74 ? 40   VAL A HG22 1 
ATOM   376  H HG23 . VAL A 1 25  ? 189.807 143.857 167.012 1.00 131.66 ? 40   VAL A HG23 1 
ATOM   377  N N    . ASP A 1 26  ? 190.611 141.416 162.164 1.00 141.10 ? 41   ASP A N    1 
ATOM   378  C CA   . ASP A 1 26  ? 190.026 140.976 160.899 1.00 141.72 ? 41   ASP A CA   1 
ATOM   379  C C    . ASP A 1 26  ? 189.274 139.666 161.112 1.00 139.21 ? 41   ASP A C    1 
ATOM   380  O O    . ASP A 1 26  ? 189.870 138.601 161.249 1.00 141.76 ? 41   ASP A O    1 
ATOM   381  C CB   . ASP A 1 26  ? 191.127 140.837 159.846 1.00 144.93 ? 41   ASP A CB   1 
ATOM   382  C CG   . ASP A 1 26  ? 190.626 140.275 158.510 1.00 150.64 ? 41   ASP A CG   1 
ATOM   383  O OD1  . ASP A 1 26  ? 189.412 140.001 158.352 1.00 151.00 ? 41   ASP A OD1  1 
ATOM   384  O OD2  . ASP A 1 26  ? 191.465 140.103 157.602 1.00 151.66 ? 41   ASP A OD2  1 
ATOM   385  H H    . ASP A 1 26  ? 191.066 140.714 162.729 1.00 142.12 ? 41   ASP A H    1 
ATOM   386  H HA   . ASP A 1 26  ? 189.315 141.721 160.538 1.00 142.60 ? 41   ASP A HA   1 
ATOM   387  H HB2  . ASP A 1 26  ? 191.569 141.818 159.673 1.00 142.63 ? 41   ASP A HB2  1 
ATOM   388  H HB3  . ASP A 1 26  ? 191.909 140.182 160.232 1.00 143.21 ? 41   ASP A HB3  1 
ATOM   389  N N    . VAL A 1 27  ? 187.949 139.752 161.156 1.00 124.61 ? 42   VAL A N    1 
ATOM   390  C CA   . VAL A 1 27  ? 187.079 138.615 161.458 1.00 128.96 ? 42   VAL A CA   1 
ATOM   391  C C    . VAL A 1 27  ? 186.676 137.813 160.226 1.00 130.04 ? 42   VAL A C    1 
ATOM   392  O O    . VAL A 1 27  ? 185.901 136.868 160.341 1.00 131.89 ? 42   VAL A O    1 
ATOM   393  C CB   . VAL A 1 27  ? 185.863 139.073 162.264 1.00 128.24 ? 42   VAL A CB   1 
ATOM   394  C CG1  . VAL A 1 27  ? 186.322 139.860 163.492 1.00 132.05 ? 42   VAL A CG1  1 
ATOM   395  C CG2  . VAL A 1 27  ? 184.907 139.948 161.452 1.00 126.93 ? 42   VAL A CG2  1 
ATOM   396  H H    . VAL A 1 27  ? 187.522 140.658 161.031 1.00 129.56 ? 42   VAL A H    1 
ATOM   397  H HA   . VAL A 1 27  ? 187.628 137.925 162.099 1.00 130.03 ? 42   VAL A HA   1 
ATOM   398  H HB   . VAL A 1 27  ? 185.319 138.193 162.604 1.00 130.96 ? 42   VAL A HB   1 
ATOM   399  H HG11 . VAL A 1 27  ? 187.204 139.390 163.929 1.00 130.72 ? 42   VAL A HG11 1 
ATOM   400  H HG12 . VAL A 1 27  ? 185.533 139.841 164.243 1.00 131.17 ? 42   VAL A HG12 1 
ATOM   401  H HG13 . VAL A 1 27  ? 186.554 140.893 163.232 1.00 130.10 ? 42   VAL A HG13 1 
ATOM   402  H HG21 . VAL A 1 27  ? 184.086 140.272 162.092 1.00 130.07 ? 42   VAL A HG21 1 
ATOM   403  H HG22 . VAL A 1 27  ? 184.491 139.373 160.625 1.00 130.35 ? 42   VAL A HG22 1 
ATOM   404  H HG23 . VAL A 1 27  ? 185.422 140.825 161.062 1.00 129.79 ? 42   VAL A HG23 1 
ATOM   405  N N    . SER A 1 28  ? 187.185 138.134 159.039 1.00 120.35 ? 43   SER A N    1 
ATOM   406  C CA   . SER A 1 28  ? 186.725 137.511 157.794 1.00 118.42 ? 43   SER A CA   1 
ATOM   407  C C    . SER A 1 28  ? 186.958 135.999 157.703 1.00 121.35 ? 43   SER A C    1 
ATOM   408  O O    . SER A 1 28  ? 186.290 135.340 156.909 1.00 131.06 ? 43   SER A O    1 
ATOM   409  C CB   . SER A 1 28  ? 187.346 138.221 156.600 1.00 123.97 ? 43   SER A CB   1 
ATOM   410  O OG   . SER A 1 28  ? 188.749 138.134 156.654 1.00 133.13 ? 43   SER A OG   1 
ATOM   411  H H    . SER A 1 28  ? 187.868 138.876 158.981 1.00 125.80 ? 43   SER A H    1 
ATOM   412  H HA   . SER A 1 28  ? 185.647 137.663 157.725 1.00 125.39 ? 43   SER A HA   1 
ATOM   413  H HB2  . SER A 1 28  ? 186.988 137.761 155.679 1.00 126.14 ? 43   SER A HB2  1 
ATOM   414  H HB3  . SER A 1 28  ? 187.052 139.270 156.606 1.00 125.88 ? 43   SER A HB3  1 
ATOM   415  H HG   . SER A 1 28  ? 189.049 138.812 157.263 1.00 127.95 ? 43   SER A HG   1 
ATOM   416  N N    . TYR A 1 29  ? 187.814 135.424 158.551 1.00 122.09 ? 44   TYR A N    1 
ATOM   417  C CA   . TYR A 1 29  ? 188.033 133.977 158.690 1.00 122.32 ? 44   TYR A CA   1 
ATOM   418  C C    . TYR A 1 29  ? 187.537 133.399 160.025 1.00 126.35 ? 44   TYR A C    1 
ATOM   419  O O    . TYR A 1 29  ? 188.003 132.358 160.477 1.00 127.32 ? 44   TYR A O    1 
ATOM   420  C CB   . TYR A 1 29  ? 189.499 133.651 158.407 1.00 128.32 ? 44   TYR A CB   1 
ATOM   421  C CG   . TYR A 1 29  ? 189.900 134.000 156.996 1.00 130.18 ? 44   TYR A CG   1 
ATOM   422  C CD1  . TYR A 1 29  ? 189.479 133.176 155.938 1.00 126.46 ? 44   TYR A CD1  1 
ATOM   423  C CD2  . TYR A 1 29  ? 190.651 135.156 156.736 1.00 127.78 ? 44   TYR A CD2  1 
ATOM   424  C CE1  . TYR A 1 29  ? 189.806 133.509 154.614 1.00 131.49 ? 44   TYR A CE1  1 
ATOM   425  C CE2  . TYR A 1 29  ? 190.980 135.494 155.413 1.00 129.44 ? 44   TYR A CE2  1 
ATOM   426  C CZ   . TYR A 1 29  ? 190.557 134.671 154.350 1.00 139.50 ? 44   TYR A CZ   1 
ATOM   427  O OH   . TYR A 1 29  ? 190.875 135.001 153.073 1.00 144.82 ? 44   TYR A OH   1 
ATOM   428  H H    . TYR A 1 29  ? 188.360 136.040 159.137 1.00 129.43 ? 44   TYR A H    1 
ATOM   429  H HA   . TYR A 1 29  ? 187.449 133.467 157.924 1.00 128.30 ? 44   TYR A HA   1 
ATOM   430  H HB2  . TYR A 1 29  ? 190.135 134.182 159.116 1.00 129.93 ? 44   TYR A HB2  1 
ATOM   431  H HB3  . TYR A 1 29  ? 189.667 132.583 158.545 1.00 129.10 ? 44   TYR A HB3  1 
ATOM   432  H HD1  . TYR A 1 29  ? 188.896 132.291 156.144 1.00 128.19 ? 44   TYR A HD1  1 
ATOM   433  H HD2  . TYR A 1 29  ? 190.964 135.796 157.547 1.00 129.31 ? 44   TYR A HD2  1 
ATOM   434  H HE1  . TYR A 1 29  ? 189.482 132.877 153.800 1.00 129.15 ? 44   TYR A HE1  1 
ATOM   435  H HE2  . TYR A 1 29  ? 191.550 136.386 155.201 1.00 129.07 ? 44   TYR A HE2  1 
ATOM   436  H HH   . TYR A 1 29  ? 190.530 134.358 152.449 1.00 131.29 ? 44   TYR A HH   1 
ATOM   437  N N    . GLY A 1 30  ? 186.596 134.066 160.693 1.00 127.53 ? 45   GLY A N    1 
ATOM   438  C CA   . GLY A 1 30  ? 185.946 133.565 161.909 1.00 126.27 ? 45   GLY A CA   1 
ATOM   439  C C    . GLY A 1 30  ? 186.637 133.947 163.216 1.00 129.70 ? 45   GLY A C    1 
ATOM   440  O O    . GLY A 1 30  ? 186.080 133.697 164.283 1.00 129.99 ? 45   GLY A O    1 
ATOM   441  H H    . GLY A 1 30  ? 186.288 134.956 160.327 1.00 128.49 ? 45   GLY A H    1 
ATOM   442  H HA2  . GLY A 1 30  ? 184.930 133.958 161.947 1.00 128.49 ? 45   GLY A HA2  1 
ATOM   443  H HA3  . GLY A 1 30  ? 185.883 132.478 161.869 1.00 127.82 ? 45   GLY A HA3  1 
ATOM   444  N N    . LEU A 1 31  ? 187.803 134.590 163.173 1.00 131.65 ? 46   LEU A N    1 
ATOM   445  C CA   . LEU A 1 31  ? 188.449 135.159 164.353 1.00 129.46 ? 46   LEU A CA   1 
ATOM   446  C C    . LEU A 1 31  ? 187.482 136.058 165.121 1.00 130.33 ? 46   LEU A C    1 
ATOM   447  O O    . LEU A 1 31  ? 186.724 136.808 164.526 1.00 136.28 ? 46   LEU A O    1 
ATOM   448  C CB   . LEU A 1 31  ? 189.727 135.887 163.913 1.00 126.90 ? 46   LEU A CB   1 
ATOM   449  C CG   . LEU A 1 31  ? 190.454 136.634 165.044 1.00 126.41 ? 46   LEU A CG   1 
ATOM   450  C CD1  . LEU A 1 31  ? 191.963 136.604 164.832 1.00 127.92 ? 46   LEU A CD1  1 
ATOM   451  C CD2  . LEU A 1 31  ? 190.049 138.104 165.097 1.00 131.31 ? 46   LEU A CD2  1 
ATOM   452  H H    . LEU A 1 31  ? 188.226 134.751 162.270 1.00 130.06 ? 46   LEU A H    1 
ATOM   453  H HA   . LEU A 1 31  ? 188.736 134.348 165.023 1.00 129.97 ? 46   LEU A HA   1 
ATOM   454  H HB2  . LEU A 1 31  ? 190.402 135.137 163.500 1.00 129.65 ? 46   LEU A HB2  1 
ATOM   455  H HB3  . LEU A 1 31  ? 189.493 136.589 163.113 1.00 129.57 ? 46   LEU A HB3  1 
ATOM   456  H HG   . LEU A 1 31  ? 190.242 136.157 166.001 1.00 129.39 ? 46   LEU A HG   1 
ATOM   457  H HD11 . LEU A 1 31  ? 192.310 135.571 164.831 1.00 129.26 ? 46   LEU A HD11 1 
ATOM   458  H HD12 . LEU A 1 31  ? 192.461 137.143 165.638 1.00 129.84 ? 46   LEU A HD12 1 
ATOM   459  H HD13 . LEU A 1 31  ? 192.213 137.067 163.878 1.00 130.60 ? 46   LEU A HD13 1 
ATOM   460  H HD21 . LEU A 1 31  ? 188.985 138.206 165.310 1.00 130.32 ? 46   LEU A HD21 1 
ATOM   461  H HD22 . LEU A 1 31  ? 190.267 138.582 164.142 1.00 131.17 ? 46   LEU A HD22 1 
ATOM   462  H HD23 . LEU A 1 31  ? 190.605 138.617 165.882 1.00 130.20 ? 46   LEU A HD23 1 
ATOM   463  N N    . GLY A 1 32  ? 187.485 135.977 166.446 1.00 123.86 ? 47   GLY A N    1 
ATOM   464  C CA   . GLY A 1 32  ? 186.604 136.789 167.285 1.00 120.73 ? 47   GLY A CA   1 
ATOM   465  C C    . GLY A 1 32  ? 185.173 136.272 167.410 1.00 118.58 ? 47   GLY A C    1 
ATOM   466  O O    . GLY A 1 32  ? 184.414 136.825 168.197 1.00 129.77 ? 47   GLY A O    1 
ATOM   467  H H    . GLY A 1 32  ? 188.123 135.340 166.900 1.00 125.31 ? 47   GLY A H    1 
ATOM   468  H HA2  . GLY A 1 32  ? 187.026 136.858 168.288 1.00 125.03 ? 47   GLY A HA2  1 
ATOM   469  H HA3  . GLY A 1 32  ? 186.554 137.796 166.873 1.00 123.89 ? 47   GLY A HA3  1 
ATOM   470  N N    . THR A 1 33  ? 184.782 135.217 166.701 1.00 116.24 ? 48   THR A N    1 
ATOM   471  C CA   . THR A 1 33  ? 183.452 134.606 166.844 1.00 125.01 ? 48   THR A CA   1 
ATOM   472  C C    . THR A 1 33  ? 183.442 133.464 167.855 1.00 121.24 ? 48   THR A C    1 
ATOM   473  O O    . THR A 1 33  ? 184.496 133.022 168.310 1.00 127.55 ? 48   THR A O    1 
ATOM   474  C CB   . THR A 1 33  ? 182.930 134.093 165.506 1.00 129.77 ? 48   THR A CB   1 
ATOM   475  O OG1  . THR A 1 33  ? 183.662 132.984 165.073 1.00 131.07 ? 48   THR A OG1  1 
ATOM   476  C CG2  . THR A 1 33  ? 182.979 135.146 164.412 1.00 125.88 ? 48   THR A CG2  1 
ATOM   477  H H    . THR A 1 33  ? 185.438 134.794 166.059 1.00 124.48 ? 48   THR A H    1 
ATOM   478  H HA   . THR A 1 33  ? 182.744 135.358 167.190 1.00 126.01 ? 48   THR A HA   1 
ATOM   479  H HB   . THR A 1 33  ? 181.892 133.787 165.634 1.00 125.99 ? 48   THR A HB   1 
ATOM   480  H HG1  . THR A 1 33  ? 184.539 133.283 164.822 1.00 126.26 ? 48   THR A HG1  1 
ATOM   481  H HG21 . THR A 1 33  ? 182.492 134.742 163.525 1.00 126.11 ? 48   THR A HG21 1 
ATOM   482  H HG22 . THR A 1 33  ? 182.440 136.033 164.743 1.00 125.56 ? 48   THR A HG22 1 
ATOM   483  H HG23 . THR A 1 33  ? 184.007 135.417 164.168 1.00 125.88 ? 48   THR A HG23 1 
ATOM   484  N N    . TYR A 1 34  ? 182.261 132.954 168.202 1.00 118.85 ? 49   TYR A N    1 
ATOM   485  C CA   . TYR A 1 34  ? 182.109 131.797 169.079 1.00 124.11 ? 49   TYR A CA   1 
ATOM   486  C C    . TYR A 1 34  ? 180.913 130.933 168.690 1.00 126.92 ? 49   TYR A C    1 
ATOM   487  O O    . TYR A 1 34  ? 179.964 131.419 168.082 1.00 131.67 ? 49   TYR A O    1 
ATOM   488  C CB   . TYR A 1 34  ? 182.017 132.254 170.537 1.00 128.02 ? 49   TYR A CB   1 
ATOM   489  C CG   . TYR A 1 34  ? 180.922 133.240 170.891 1.00 126.46 ? 49   TYR A CG   1 
ATOM   490  C CD1  . TYR A 1 34  ? 179.579 132.840 170.965 1.00 129.89 ? 49   TYR A CD1  1 
ATOM   491  C CD2  . TYR A 1 34  ? 181.270 134.552 171.247 1.00 126.53 ? 49   TYR A CD2  1 
ATOM   492  C CE1  . TYR A 1 34  ? 178.587 133.747 171.383 1.00 131.72 ? 49   TYR A CE1  1 
ATOM   493  C CE2  . TYR A 1 34  ? 180.286 135.457 171.676 1.00 126.60 ? 49   TYR A CE2  1 
ATOM   494  C CZ   . TYR A 1 34  ? 178.942 135.061 171.746 1.00 129.54 ? 49   TYR A CZ   1 
ATOM   495  O OH   . TYR A 1 34  ? 178.005 135.938 172.189 1.00 130.72 ? 49   TYR A OH   1 
ATOM   496  H H    . TYR A 1 34  ? 181.415 133.330 167.797 1.00 127.72 ? 49   TYR A H    1 
ATOM   497  H HA   . TYR A 1 34  ? 182.996 131.169 168.985 1.00 128.02 ? 49   TYR A HA   1 
ATOM   498  H HB2  . TYR A 1 34  ? 181.914 131.377 171.175 1.00 128.73 ? 49   TYR A HB2  1 
ATOM   499  H HB3  . TYR A 1 34  ? 182.969 132.724 170.786 1.00 129.37 ? 49   TYR A HB3  1 
ATOM   500  H HD1  . TYR A 1 34  ? 179.301 131.824 170.724 1.00 128.97 ? 49   TYR A HD1  1 
ATOM   501  H HD2  . TYR A 1 34  ? 182.304 134.863 171.224 1.00 128.65 ? 49   TYR A HD2  1 
ATOM   502  H HE1  . TYR A 1 34  ? 177.557 133.430 171.442 1.00 129.44 ? 49   TYR A HE1  1 
ATOM   503  H HE2  . TYR A 1 34  ? 180.559 136.457 171.978 1.00 128.63 ? 49   TYR A HE2  1 
ATOM   504  H HH   . TYR A 1 34  ? 177.203 135.477 172.444 1.00 128.92 ? 49   TYR A HH   1 
ATOM   505  N N    . TYR A 1 35  ? 180.935 129.653 169.048 1.00 126.54 ? 50   TYR A N    1 
ATOM   506  C CA   . TYR A 1 35  ? 179.814 128.746 168.816 1.00 122.38 ? 50   TYR A CA   1 
ATOM   507  C C    . TYR A 1 35  ? 178.619 129.062 169.713 1.00 127.51 ? 50   TYR A C    1 
ATOM   508  O O    . TYR A 1 35  ? 178.764 129.321 170.906 1.00 128.53 ? 50   TYR A O    1 
ATOM   509  C CB   . TYR A 1 35  ? 180.266 127.301 168.991 1.00 124.70 ? 50   TYR A CB   1 
ATOM   510  C CG   . TYR A 1 35  ? 181.226 126.873 167.908 1.00 127.28 ? 50   TYR A CG   1 
ATOM   511  C CD1  . TYR A 1 35  ? 180.751 126.690 166.600 1.00 130.85 ? 50   TYR A CD1  1 
ATOM   512  C CD2  . TYR A 1 35  ? 182.586 126.690 168.192 1.00 130.01 ? 50   TYR A CD2  1 
ATOM   513  C CE1  . TYR A 1 35  ? 181.637 126.337 165.572 1.00 128.82 ? 50   TYR A CE1  1 
ATOM   514  C CE2  . TYR A 1 35  ? 183.476 126.322 167.169 1.00 131.59 ? 50   TYR A CE2  1 
ATOM   515  C CZ   . TYR A 1 35  ? 183.001 126.155 165.854 1.00 130.87 ? 50   TYR A CZ   1 
ATOM   516  O OH   . TYR A 1 35  ? 183.858 125.827 164.858 1.00 135.97 ? 50   TYR A OH   1 
ATOM   517  H H    . TYR A 1 35  ? 181.747 129.306 169.538 1.00 130.05 ? 50   TYR A H    1 
ATOM   518  H HA   . TYR A 1 35  ? 179.489 128.867 167.783 1.00 128.43 ? 50   TYR A HA   1 
ATOM   519  H HB2  . TYR A 1 35  ? 180.726 127.177 169.971 1.00 129.58 ? 50   TYR A HB2  1 
ATOM   520  H HB3  . TYR A 1 35  ? 179.393 126.649 168.947 1.00 128.82 ? 50   TYR A HB3  1 
ATOM   521  H HD1  . TYR A 1 35  ? 179.703 126.824 166.381 1.00 129.89 ? 50   TYR A HD1  1 
ATOM   522  H HD2  . TYR A 1 35  ? 182.954 126.840 169.196 1.00 130.01 ? 50   TYR A HD2  1 
ATOM   523  H HE1  . TYR A 1 35  ? 181.273 126.194 164.565 1.00 129.55 ? 50   TYR A HE1  1 
ATOM   524  H HE2  . TYR A 1 35  ? 184.524 126.190 167.389 1.00 130.07 ? 50   TYR A HE2  1 
ATOM   525  H HH   . TYR A 1 35  ? 184.705 125.547 165.212 1.00 130.27 ? 50   TYR A HH   1 
ATOM   526  N N    . ILE A 1 36  ? 177.421 129.053 169.135 1.00 136.92 ? 51   ILE A N    1 
ATOM   527  C CA   . ILE A 1 36  ? 176.208 129.557 169.779 1.00 136.96 ? 51   ILE A CA   1 
ATOM   528  C C    . ILE A 1 36  ? 175.587 128.490 170.680 1.00 137.86 ? 51   ILE A C    1 
ATOM   529  O O    . ILE A 1 36  ? 175.047 127.504 170.186 1.00 142.70 ? 51   ILE A O    1 
ATOM   530  C CB   . ILE A 1 36  ? 175.216 130.042 168.704 1.00 136.41 ? 51   ILE A CB   1 
ATOM   531  C CG1  . ILE A 1 36  ? 175.823 131.209 167.897 1.00 137.97 ? 51   ILE A CG1  1 
ATOM   532  C CG2  . ILE A 1 36  ? 173.893 130.487 169.350 1.00 134.19 ? 51   ILE A CG2  1 
ATOM   533  C CD1  . ILE A 1 36  ? 175.051 131.540 166.620 1.00 141.76 ? 51   ILE A CD1  1 
ATOM   534  H H    . ILE A 1 36  ? 177.357 128.775 168.166 1.00 136.41 ? 51   ILE A H    1 
ATOM   535  H HA   . ILE A 1 36  ? 176.465 130.416 170.398 1.00 136.47 ? 51   ILE A HA   1 
ATOM   536  H HB   . ILE A 1 36  ? 175.008 129.218 168.023 1.00 136.73 ? 51   ILE A HB   1 
ATOM   537  H HG12 . ILE A 1 36  ? 175.874 132.099 168.526 1.00 136.45 ? 51   ILE A HG12 1 
ATOM   538  H HG13 . ILE A 1 36  ? 176.840 130.965 167.589 1.00 136.84 ? 51   ILE A HG13 1 
ATOM   539  H HG21 . ILE A 1 36  ? 173.194 130.832 168.588 1.00 136.33 ? 51   ILE A HG21 1 
ATOM   540  H HG22 . ILE A 1 36  ? 174.076 131.299 170.054 1.00 137.31 ? 51   ILE A HG22 1 
ATOM   541  H HG23 . ILE A 1 36  ? 173.416 129.658 169.871 1.00 136.09 ? 51   ILE A HG23 1 
ATOM   542  H HD11 . ILE A 1 36  ? 175.570 132.336 166.085 1.00 137.42 ? 51   ILE A HD11 1 
ATOM   543  H HD12 . ILE A 1 36  ? 174.998 130.659 165.978 1.00 137.28 ? 51   ILE A HD12 1 
ATOM   544  H HD13 . ILE A 1 36  ? 174.043 131.883 166.850 1.00 137.53 ? 51   ILE A HD13 1 
ATOM   545  N N    . LEU A 1 37  ? 175.598 128.715 171.995 1.00 143.64 ? 52   LEU A N    1 
ATOM   546  C CA   . LEU A 1 37  ? 174.922 127.866 172.982 1.00 144.16 ? 52   LEU A CA   1 
ATOM   547  C C    . LEU A 1 37  ? 175.260 126.380 172.771 1.00 146.25 ? 52   LEU A C    1 
ATOM   548  O O    . LEU A 1 37  ? 176.429 126.003 172.784 1.00 149.67 ? 52   LEU A O    1 
ATOM   549  C CB   . LEU A 1 37  ? 173.410 128.176 172.981 1.00 148.42 ? 52   LEU A CB   1 
ATOM   550  C CG   . LEU A 1 37  ? 173.049 129.643 173.251 1.00 149.62 ? 52   LEU A CG   1 
ATOM   551  C CD1  . LEU A 1 37  ? 171.545 129.833 173.091 1.00 149.30 ? 52   LEU A CD1  1 
ATOM   552  C CD2  . LEU A 1 37  ? 173.437 130.071 174.664 1.00 145.60 ? 52   LEU A CD2  1 
ATOM   553  H H    . LEU A 1 37  ? 176.102 129.523 172.332 1.00 145.55 ? 52   LEU A H    1 
ATOM   554  H HA   . LEU A 1 37  ? 175.311 128.114 173.970 1.00 145.85 ? 52   LEU A HA   1 
ATOM   555  H HB2  . LEU A 1 37  ? 172.998 127.900 172.011 1.00 146.63 ? 52   LEU A HB2  1 
ATOM   556  H HB3  . LEU A 1 37  ? 172.924 127.562 173.741 1.00 146.36 ? 52   LEU A HB3  1 
ATOM   557  H HG   . LEU A 1 37  ? 173.550 130.293 172.533 1.00 146.67 ? 52   LEU A HG   1 
ATOM   558  H HD11 . LEU A 1 37  ? 171.247 129.565 172.078 1.00 146.37 ? 52   LEU A HD11 1 
ATOM   559  H HD12 . LEU A 1 37  ? 171.010 129.204 173.803 1.00 147.07 ? 52   LEU A HD12 1 
ATOM   560  H HD13 . LEU A 1 37  ? 171.285 130.877 173.267 1.00 146.71 ? 52   LEU A HD13 1 
ATOM   561  H HD21 . LEU A 1 37  ? 174.520 130.031 174.783 1.00 145.86 ? 52   LEU A HD21 1 
ATOM   562  H HD22 . LEU A 1 37  ? 173.112 131.098 174.838 1.00 146.16 ? 52   LEU A HD22 1 
ATOM   563  H HD23 . LEU A 1 37  ? 172.967 129.416 175.397 1.00 146.83 ? 52   LEU A HD23 1 
ATOM   564  N N    . ASP A 1 38  ? 174.252 125.537 172.559 1.00 157.77 ? 53   ASP A N    1 
ATOM   565  C CA   . ASP A 1 38  ? 174.365 124.122 172.206 1.00 162.79 ? 53   ASP A CA   1 
ATOM   566  C C    . ASP A 1 38  ? 173.850 123.828 170.785 1.00 162.27 ? 53   ASP A C    1 
ATOM   567  O O    . ASP A 1 38  ? 173.598 122.673 170.443 1.00 161.46 ? 53   ASP A O    1 
ATOM   568  C CB   . ASP A 1 38  ? 173.623 123.274 173.250 1.00 165.04 ? 53   ASP A CB   1 
ATOM   569  C CG   . ASP A 1 38  ? 172.113 123.543 173.327 1.00 165.81 ? 53   ASP A CG   1 
ATOM   570  O OD1  . ASP A 1 38  ? 171.628 124.550 172.764 1.00 159.89 ? 53   ASP A OD1  1 
ATOM   571  O OD2  . ASP A 1 38  ? 171.408 122.746 173.987 1.00 168.84 ? 53   ASP A OD2  1 
ATOM   572  H H    . ASP A 1 38  ? 173.311 125.899 172.602 1.00 159.35 ? 53   ASP A H    1 
ATOM   573  H HA   . ASP A 1 38  ? 175.414 123.827 172.226 1.00 160.92 ? 53   ASP A HA   1 
ATOM   574  H HB2  . ASP A 1 38  ? 173.791 122.220 173.033 1.00 161.06 ? 53   ASP A HB2  1 
ATOM   575  H HB3  . ASP A 1 38  ? 174.061 123.474 174.228 1.00 161.61 ? 53   ASP A HB3  1 
ATOM   576  N N    . ARG A 1 39  ? 173.664 124.854 169.952 1.00 139.29 ? 54   ARG A N    1 
ATOM   577  C CA   . ARG A 1 39  ? 173.128 124.726 168.593 1.00 133.42 ? 54   ARG A CA   1 
ATOM   578  C C    . ARG A 1 39  ? 174.179 124.282 167.587 1.00 137.46 ? 54   ARG A C    1 
ATOM   579  O O    . ARG A 1 39  ? 175.346 124.647 167.697 1.00 144.17 ? 54   ARG A O    1 
ATOM   580  C CB   . ARG A 1 39  ? 172.548 126.067 168.150 1.00 138.13 ? 54   ARG A CB   1 
ATOM   581  C CG   . ARG A 1 39  ? 171.381 126.480 169.043 1.00 141.04 ? 54   ARG A CG   1 
ATOM   582  C CD   . ARG A 1 39  ? 170.764 127.768 168.518 1.00 141.12 ? 54   ARG A CD   1 
ATOM   583  N NE   . ARG A 1 39  ? 169.617 128.152 169.348 1.00 144.42 ? 54   ARG A NE   1 
ATOM   584  C CZ   . ARG A 1 39  ? 168.894 129.241 169.214 1.00 146.37 ? 54   ARG A CZ   1 
ATOM   585  N NH1  . ARG A 1 39  ? 167.889 129.453 170.007 1.00 148.92 ? 54   ARG A NH1  1 
ATOM   586  N NH2  . ARG A 1 39  ? 169.148 130.132 168.300 1.00 143.14 ? 54   ARG A NH2  1 
ATOM   587  H H    . ARG A 1 39  ? 173.974 125.764 170.257 1.00 141.79 ? 54   ARG A H    1 
ATOM   588  H HA   . ARG A 1 39  ? 172.334 123.980 168.590 1.00 140.86 ? 54   ARG A HA   1 
ATOM   589  H HB2  . ARG A 1 39  ? 173.321 126.834 168.180 1.00 141.33 ? 54   ARG A HB2  1 
ATOM   590  H HB3  . ARG A 1 39  ? 172.190 125.976 167.125 1.00 141.79 ? 54   ARG A HB3  1 
ATOM   591  H HG2  . ARG A 1 39  ? 170.628 125.693 169.037 1.00 141.42 ? 54   ARG A HG2  1 
ATOM   592  H HG3  . ARG A 1 39  ? 171.728 126.642 170.064 1.00 141.32 ? 54   ARG A HG3  1 
ATOM   593  H HD2  . ARG A 1 39  ? 171.517 128.555 168.536 1.00 140.44 ? 54   ARG A HD2  1 
ATOM   594  H HD3  . ARG A 1 39  ? 170.435 127.610 167.491 1.00 141.00 ? 54   ARG A HD3  1 
ATOM   595  H HE   . ARG A 1 39  ? 169.338 127.513 170.080 1.00 141.62 ? 54   ARG A HE   1 
ATOM   596  H HH11 . ARG A 1 39  ? 167.659 128.777 170.722 1.00 141.78 ? 54   ARG A HH11 1 
ATOM   597  H HH12 . ARG A 1 39  ? 167.327 130.285 169.903 1.00 142.49 ? 54   ARG A HH12 1 
ATOM   598  H HH21 . ARG A 1 39  ? 169.907 129.969 167.654 1.00 140.88 ? 54   ARG A HH21 1 
ATOM   599  H HH22 . ARG A 1 39  ? 168.579 130.963 168.229 1.00 141.56 ? 54   ARG A HH22 1 
ATOM   600  N N    . VAL A 1 40  ? 173.753 123.570 166.549 1.00 118.84 ? 55   VAL A N    1 
ATOM   601  C CA   . VAL A 1 40  ? 174.560 123.318 165.350 1.00 114.70 ? 55   VAL A CA   1 
ATOM   602  C C    . VAL A 1 40  ? 173.826 123.834 164.127 1.00 118.42 ? 55   VAL A C    1 
ATOM   603  O O    . VAL A 1 40  ? 172.716 123.393 163.842 1.00 126.39 ? 55   VAL A O    1 
ATOM   604  C CB   . VAL A 1 40  ? 174.906 121.832 165.204 1.00 120.77 ? 55   VAL A CB   1 
ATOM   605  C CG1  . VAL A 1 40  ? 175.707 121.564 163.928 1.00 121.78 ? 55   VAL A CG1  1 
ATOM   606  C CG2  . VAL A 1 40  ? 175.749 121.352 166.386 1.00 127.48 ? 55   VAL A CG2  1 
ATOM   607  H H    . VAL A 1 40  ? 172.780 123.302 166.525 1.00 122.28 ? 55   VAL A H    1 
ATOM   608  H HA   . VAL A 1 40  ? 175.504 123.860 165.421 1.00 122.01 ? 55   VAL A HA   1 
ATOM   609  H HB   . VAL A 1 40  ? 173.988 121.246 165.170 1.00 122.99 ? 55   VAL A HB   1 
ATOM   610  H HG11 . VAL A 1 40  ? 175.105 121.786 163.046 1.00 122.19 ? 55   VAL A HG11 1 
ATOM   611  H HG12 . VAL A 1 40  ? 176.609 122.175 163.915 1.00 122.69 ? 55   VAL A HG12 1 
ATOM   612  H HG13 . VAL A 1 40  ? 175.990 120.512 163.885 1.00 122.48 ? 55   VAL A HG13 1 
ATOM   613  H HG21 . VAL A 1 40  ? 175.183 121.442 167.312 1.00 123.92 ? 55   VAL A HG21 1 
ATOM   614  H HG22 . VAL A 1 40  ? 176.014 120.304 166.250 1.00 123.25 ? 55   VAL A HG22 1 
ATOM   615  H HG23 . VAL A 1 40  ? 176.660 121.947 166.463 1.00 122.17 ? 55   VAL A HG23 1 
ATOM   616  N N    . TYR A 1 41  ? 174.454 124.735 163.383 1.00 114.82 ? 56   TYR A N    1 
ATOM   617  C CA   . TYR A 1 41  ? 173.993 125.220 162.086 1.00 119.22 ? 56   TYR A CA   1 
ATOM   618  C C    . TYR A 1 41  ? 174.851 124.593 160.990 1.00 120.59 ? 56   TYR A C    1 
ATOM   619  O O    . TYR A 1 41  ? 176.050 124.446 161.185 1.00 130.03 ? 56   TYR A O    1 
ATOM   620  C CB   . TYR A 1 41  ? 174.110 126.742 162.049 1.00 118.55 ? 56   TYR A CB   1 
ATOM   621  C CG   . TYR A 1 41  ? 173.225 127.481 163.029 1.00 116.05 ? 56   TYR A CG   1 
ATOM   622  C CD1  . TYR A 1 41  ? 173.690 127.787 164.317 1.00 118.75 ? 56   TYR A CD1  1 
ATOM   623  C CD2  . TYR A 1 41  ? 171.948 127.904 162.632 1.00 122.69 ? 56   TYR A CD2  1 
ATOM   624  C CE1  . TYR A 1 41  ? 172.886 128.519 165.206 1.00 120.69 ? 56   TYR A CE1  1 
ATOM   625  C CE2  . TYR A 1 41  ? 171.144 128.645 163.512 1.00 124.75 ? 56   TYR A CE2  1 
ATOM   626  C CZ   . TYR A 1 41  ? 171.614 128.957 164.800 1.00 123.73 ? 56   TYR A CZ   1 
ATOM   627  O OH   . TYR A 1 41  ? 170.829 129.673 165.644 1.00 128.00 ? 56   TYR A OH   1 
ATOM   628  H H    . TYR A 1 41  ? 175.377 125.026 163.673 1.00 122.68 ? 56   TYR A H    1 
ATOM   629  H HA   . TYR A 1 41  ? 172.952 124.945 161.920 1.00 123.86 ? 56   TYR A HA   1 
ATOM   630  H HB2  . TYR A 1 41  ? 175.146 127.020 162.240 1.00 122.99 ? 56   TYR A HB2  1 
ATOM   631  H HB3  . TYR A 1 41  ? 173.867 127.084 161.043 1.00 122.59 ? 56   TYR A HB3  1 
ATOM   632  H HD1  . TYR A 1 41  ? 174.678 127.472 164.621 1.00 124.12 ? 56   TYR A HD1  1 
ATOM   633  H HD2  . TYR A 1 41  ? 171.588 127.672 161.641 1.00 123.92 ? 56   TYR A HD2  1 
ATOM   634  H HE1  . TYR A 1 41  ? 173.242 128.763 166.196 1.00 123.88 ? 56   TYR A HE1  1 
ATOM   635  H HE2  . TYR A 1 41  ? 170.165 128.974 163.197 1.00 124.26 ? 56   TYR A HE2  1 
ATOM   636  H HH   . TYR A 1 41  ? 170.080 130.037 165.168 1.00 124.18 ? 56   TYR A HH   1 
ATOM   637  N N    . LEU A 1 42  ? 174.285 124.211 159.846 1.00 117.84 ? 57   LEU A N    1 
ATOM   638  C CA   . LEU A 1 42  ? 175.033 123.563 158.764 1.00 120.11 ? 57   LEU A CA   1 
ATOM   639  C C    . LEU A 1 42  ? 174.851 124.283 157.434 1.00 124.73 ? 57   LEU A C    1 
ATOM   640  O O    . LEU A 1 42  ? 173.744 124.692 157.105 1.00 129.77 ? 57   LEU A O    1 
ATOM   641  C CB   . LEU A 1 42  ? 174.580 122.106 158.603 1.00 117.69 ? 57   LEU A CB   1 
ATOM   642  C CG   . LEU A 1 42  ? 174.880 121.188 159.789 1.00 126.70 ? 57   LEU A CG   1 
ATOM   643  C CD1  . LEU A 1 42  ? 174.332 119.799 159.488 1.00 129.05 ? 57   LEU A CD1  1 
ATOM   644  C CD2  . LEU A 1 42  ? 176.377 121.051 160.040 1.00 131.89 ? 57   LEU A CD2  1 
ATOM   645  H H    . LEU A 1 42  ? 173.295 124.362 159.715 1.00 125.09 ? 57   LEU A H    1 
ATOM   646  H HA   . LEU A 1 42  ? 176.100 123.572 158.983 1.00 125.75 ? 57   LEU A HA   1 
ATOM   647  H HB2  . LEU A 1 42  ? 173.505 122.097 158.421 1.00 124.47 ? 57   LEU A HB2  1 
ATOM   648  H HB3  . LEU A 1 42  ? 175.066 121.688 157.721 1.00 125.10 ? 57   LEU A HB3  1 
ATOM   649  H HG   . LEU A 1 42  ? 174.394 121.570 160.687 1.00 126.21 ? 57   LEU A HG   1 
ATOM   650  H HD11 . LEU A 1 42  ? 174.517 119.140 160.337 1.00 126.16 ? 57   LEU A HD11 1 
ATOM   651  H HD12 . LEU A 1 42  ? 173.256 119.858 159.321 1.00 126.23 ? 57   LEU A HD12 1 
ATOM   652  H HD13 . LEU A 1 42  ? 174.813 119.387 158.601 1.00 126.51 ? 57   LEU A HD13 1 
ATOM   653  H HD21 . LEU A 1 42  ? 176.778 122.011 160.365 1.00 126.49 ? 57   LEU A HD21 1 
ATOM   654  H HD22 . LEU A 1 42  ? 176.884 120.724 159.132 1.00 126.31 ? 57   LEU A HD22 1 
ATOM   655  H HD23 . LEU A 1 42  ? 176.551 120.325 160.834 1.00 127.12 ? 57   LEU A HD23 1 
ATOM   656  N N    . ASN A 1 43  ? 175.925 124.364 156.650 1.00 138.17 ? 58   ASN A N    1 
ATOM   657  C CA   . ASN A 1 43  ? 175.982 124.902 155.288 1.00 137.77 ? 58   ASN A CA   1 
ATOM   658  C C    . ASN A 1 43  ? 175.080 126.126 155.053 1.00 140.60 ? 58   ASN A C    1 
ATOM   659  O O    . ASN A 1 43  ? 174.158 126.080 154.239 1.00 145.45 ? 58   ASN A O    1 
ATOM   660  C CB   . ASN A 1 43  ? 175.726 123.760 154.289 1.00 136.89 ? 58   ASN A CB   1 
ATOM   661  C CG   . ASN A 1 43  ? 176.041 124.179 152.864 1.00 144.66 ? 58   ASN A CG   1 
ATOM   662  O OD1  . ASN A 1 43  ? 176.817 125.107 152.651 1.00 145.80 ? 58   ASN A OD1  1 
ATOM   663  N ND2  . ASN A 1 43  ? 175.460 123.512 151.884 1.00 147.51 ? 58   ASN A ND2  1 
ATOM   664  H H    . ASN A 1 43  ? 176.796 124.031 157.039 1.00 141.89 ? 58   ASN A H    1 
ATOM   665  H HA   . ASN A 1 43  ? 177.004 125.249 155.132 1.00 141.97 ? 58   ASN A HA   1 
ATOM   666  H HB2  . ASN A 1 43  ? 176.355 122.903 154.530 1.00 141.13 ? 58   ASN A HB2  1 
ATOM   667  H HB3  . ASN A 1 43  ? 174.684 123.450 154.353 1.00 140.84 ? 58   ASN A HB3  1 
ATOM   668  H HD21 . ASN A 1 43  ? 174.958 122.664 152.106 1.00 141.55 ? 58   ASN A HD21 1 
ATOM   669  N N    . THR A 1 44  ? 175.225 127.170 155.867 1.00 138.91 ? 59   THR A N    1 
ATOM   670  C CA   . THR A 1 44  ? 174.273 128.292 155.903 1.00 143.46 ? 59   THR A CA   1 
ATOM   671  C C    . THR A 1 44  ? 174.899 129.566 156.453 1.00 141.07 ? 59   THR A C    1 
ATOM   672  O O    . THR A 1 44  ? 175.931 129.513 157.119 1.00 147.15 ? 59   THR A O    1 
ATOM   673  C CB   . THR A 1 44  ? 173.028 127.907 156.717 1.00 146.65 ? 59   THR A CB   1 
ATOM   674  O OG1  . THR A 1 44  ? 172.017 128.860 156.508 1.00 151.37 ? 59   THR A OG1  1 
ATOM   675  C CG2  . THR A 1 44  ? 173.259 127.839 158.225 1.00 140.40 ? 59   THR A CG2  1 
ATOM   676  H H    . THR A 1 44  ? 176.011 127.183 156.500 1.00 140.48 ? 59   THR A H    1 
ATOM   677  H HA   . THR A 1 44  ? 173.949 128.506 154.886 1.00 141.36 ? 59   THR A HA   1 
ATOM   678  H HB   . THR A 1 44  ? 172.658 126.943 156.368 1.00 141.60 ? 59   THR A HB   1 
ATOM   679  H HG1  . THR A 1 44  ? 171.218 128.519 156.915 1.00 141.67 ? 59   THR A HG1  1 
ATOM   680  H HG21 . THR A 1 44  ? 172.365 127.453 158.714 1.00 140.29 ? 59   THR A HG21 1 
ATOM   681  H HG22 . THR A 1 44  ? 173.484 128.828 158.625 1.00 140.38 ? 59   THR A HG22 1 
ATOM   682  H HG23 . THR A 1 44  ? 174.091 127.169 158.440 1.00 140.47 ? 59   THR A HG23 1 
ATOM   683  N N    . THR A 1 45  ? 174.281 130.717 156.198 1.00 125.37 ? 60   THR A N    1 
ATOM   684  C CA   . THR A 1 45  ? 174.645 131.998 156.806 1.00 118.17 ? 60   THR A CA   1 
ATOM   685  C C    . THR A 1 45  ? 173.562 132.475 157.763 1.00 120.32 ? 60   THR A C    1 
ATOM   686  O O    . THR A 1 45  ? 172.373 132.417 157.467 1.00 125.81 ? 60   THR A O    1 
ATOM   687  C CB   . THR A 1 45  ? 174.972 133.083 155.781 1.00 124.42 ? 60   THR A CB   1 
ATOM   688  O OG1  . THR A 1 45  ? 173.880 133.343 154.938 1.00 138.14 ? 60   THR A OG1  1 
ATOM   689  C CG2  . THR A 1 45  ? 176.150 132.697 154.898 1.00 127.19 ? 60   THR A CG2  1 
ATOM   690  H H    . THR A 1 45  ? 173.408 130.683 155.690 1.00 127.40 ? 60   THR A H    1 
ATOM   691  H HA   . THR A 1 45  ? 175.551 131.849 157.393 1.00 126.34 ? 60   THR A HA   1 
ATOM   692  H HB   . THR A 1 45  ? 175.231 133.995 156.318 1.00 126.24 ? 60   THR A HB   1 
ATOM   693  H HG1  . THR A 1 45  ? 174.149 134.024 154.318 1.00 127.94 ? 60   THR A HG1  1 
ATOM   694  H HG21 . THR A 1 45  ? 176.398 133.523 154.232 1.00 127.78 ? 60   THR A HG21 1 
ATOM   695  H HG22 . THR A 1 45  ? 177.013 132.488 155.530 1.00 125.64 ? 60   THR A HG22 1 
ATOM   696  H HG23 . THR A 1 45  ? 175.911 131.814 154.306 1.00 126.47 ? 60   THR A HG23 1 
ATOM   697  N N    . ILE A 1 46  ? 173.972 132.951 158.930 1.00 125.14 ? 61   ILE A N    1 
ATOM   698  C CA   . ILE A 1 46  ? 173.104 133.398 160.017 1.00 124.20 ? 61   ILE A CA   1 
ATOM   699  C C    . ILE A 1 46  ? 173.449 134.832 160.370 1.00 127.97 ? 61   ILE A C    1 
ATOM   700  O O    . ILE A 1 46  ? 174.626 135.170 160.421 1.00 138.07 ? 61   ILE A O    1 
ATOM   701  C CB   . ILE A 1 46  ? 173.318 132.484 161.237 1.00 124.92 ? 61   ILE A CB   1 
ATOM   702  C CG1  . ILE A 1 46  ? 172.913 131.029 160.962 1.00 132.00 ? 61   ILE A CG1  1 
ATOM   703  C CG2  . ILE A 1 46  ? 172.608 132.985 162.496 1.00 124.66 ? 61   ILE A CG2  1 
ATOM   704  C CD1  . ILE A 1 46  ? 171.441 130.826 160.594 1.00 139.28 ? 61   ILE A CD1  1 
ATOM   705  H H    . ILE A 1 46  ? 174.968 132.979 159.100 1.00 130.51 ? 61   ILE A H    1 
ATOM   706  H HA   . ILE A 1 46  ? 172.057 133.367 159.717 1.00 129.23 ? 61   ILE A HA   1 
ATOM   707  H HB   . ILE A 1 46  ? 174.385 132.479 161.463 1.00 129.70 ? 61   ILE A HB   1 
ATOM   708  H HG12 . ILE A 1 46  ? 173.529 130.635 160.153 1.00 129.82 ? 61   ILE A HG12 1 
ATOM   709  H HG13 . ILE A 1 46  ? 173.135 130.432 161.847 1.00 129.42 ? 61   ILE A HG13 1 
ATOM   710  H HG21 . ILE A 1 46  ? 173.086 133.899 162.850 1.00 128.88 ? 61   ILE A HG21 1 
ATOM   711  H HG22 . ILE A 1 46  ? 171.556 133.181 162.293 1.00 129.32 ? 61   ILE A HG22 1 
ATOM   712  H HG23 . ILE A 1 46  ? 172.690 132.242 163.289 1.00 129.08 ? 61   ILE A HG23 1 
ATOM   713  H HD11 . ILE A 1 46  ? 171.263 129.767 160.407 1.00 131.17 ? 61   ILE A HD11 1 
ATOM   714  H HD12 . ILE A 1 46  ? 171.186 131.378 159.690 1.00 130.64 ? 61   ILE A HD12 1 
ATOM   715  H HD13 . ILE A 1 46  ? 170.796 131.146 161.412 1.00 131.25 ? 61   ILE A HD13 1 
ATOM   716  N N    . LEU A 1 47  ? 172.460 135.663 160.682 1.00 126.14 ? 62   LEU A N    1 
ATOM   717  C CA   . LEU A 1 47  ? 172.701 136.907 161.402 1.00 126.94 ? 62   LEU A CA   1 
ATOM   718  C C    . LEU A 1 47  ? 172.504 136.638 162.885 1.00 129.53 ? 62   LEU A C    1 
ATOM   719  O O    . LEU A 1 47  ? 171.468 136.121 163.294 1.00 133.63 ? 62   LEU A O    1 
ATOM   720  C CB   . LEU A 1 47  ? 171.751 138.005 160.923 1.00 128.97 ? 62   LEU A CB   1 
ATOM   721  C CG   . LEU A 1 47  ? 172.076 138.527 159.520 1.00 131.44 ? 62   LEU A CG   1 
ATOM   722  C CD1  . LEU A 1 47  ? 170.912 139.363 159.003 1.00 133.48 ? 62   LEU A CD1  1 
ATOM   723  C CD2  . LEU A 1 47  ? 173.321 139.412 159.524 1.00 134.62 ? 62   LEU A CD2  1 
ATOM   724  H H    . LEU A 1 47  ? 171.509 135.326 160.629 1.00 129.76 ? 62   LEU A H    1 
ATOM   725  H HA   . LEU A 1 47  ? 173.728 137.241 161.252 1.00 129.79 ? 62   LEU A HA   1 
ATOM   726  H HB2  . LEU A 1 47  ? 170.734 137.611 160.932 1.00 130.90 ? 62   LEU A HB2  1 
ATOM   727  H HB3  . LEU A 1 47  ? 171.791 138.841 161.622 1.00 129.11 ? 62   LEU A HB3  1 
ATOM   728  H HG   . LEU A 1 47  ? 172.230 137.691 158.838 1.00 130.41 ? 62   LEU A HG   1 
ATOM   729  H HD11 . LEU A 1 47  ? 171.139 139.731 158.003 1.00 131.07 ? 62   LEU A HD11 1 
ATOM   730  H HD12 . LEU A 1 47  ? 170.733 140.210 159.666 1.00 130.32 ? 62   LEU A HD12 1 
ATOM   731  H HD13 . LEU A 1 47  ? 170.013 138.748 158.952 1.00 130.77 ? 62   LEU A HD13 1 
ATOM   732  H HD21 . LEU A 1 47  ? 174.190 138.840 159.847 1.00 130.89 ? 62   LEU A HD21 1 
ATOM   733  H HD22 . LEU A 1 47  ? 173.178 140.262 160.192 1.00 129.92 ? 62   LEU A HD22 1 
ATOM   734  H HD23 . LEU A 1 47  ? 173.510 139.780 158.516 1.00 131.63 ? 62   LEU A HD23 1 
ATOM   735  N N    . PHE A 1 48  ? 173.486 136.989 163.696 1.00 128.26 ? 63   PHE A N    1 
ATOM   736  C CA   . PHE A 1 48  ? 173.472 136.749 165.131 1.00 126.97 ? 63   PHE A CA   1 
ATOM   737  C C    . PHE A 1 48  ? 174.024 137.959 165.872 1.00 129.13 ? 63   PHE A C    1 
ATOM   738  O O    . PHE A 1 48  ? 174.936 138.618 165.385 1.00 128.92 ? 63   PHE A O    1 
ATOM   739  C CB   . PHE A 1 48  ? 174.275 135.483 165.422 1.00 124.01 ? 63   PHE A CB   1 
ATOM   740  C CG   . PHE A 1 48  ? 174.368 135.141 166.888 1.00 125.17 ? 63   PHE A CG   1 
ATOM   741  C CD1  . PHE A 1 48  ? 173.261 134.599 167.559 1.00 126.96 ? 63   PHE A CD1  1 
ATOM   742  C CD2  . PHE A 1 48  ? 175.563 135.364 167.580 1.00 129.16 ? 63   PHE A CD2  1 
ATOM   743  C CE1  . PHE A 1 48  ? 173.356 134.281 168.922 1.00 128.88 ? 63   PHE A CE1  1 
ATOM   744  C CE2  . PHE A 1 48  ? 175.662 135.047 168.942 1.00 129.25 ? 63   PHE A CE2  1 
ATOM   745  C CZ   . PHE A 1 48  ? 174.556 134.507 169.616 1.00 129.27 ? 63   PHE A CZ   1 
ATOM   746  H H    . PHE A 1 48  ? 174.320 137.400 163.300 1.00 128.61 ? 63   PHE A H    1 
ATOM   747  H HA   . PHE A 1 48  ? 172.449 136.590 165.472 1.00 128.02 ? 63   PHE A HA   1 
ATOM   748  H HB2  . PHE A 1 48  ? 173.809 134.642 164.908 1.00 127.91 ? 63   PHE A HB2  1 
ATOM   749  H HB3  . PHE A 1 48  ? 175.280 135.601 165.017 1.00 127.93 ? 63   PHE A HB3  1 
ATOM   750  H HD1  . PHE A 1 48  ? 172.339 134.417 167.026 1.00 128.09 ? 63   PHE A HD1  1 
ATOM   751  H HD2  . PHE A 1 48  ? 176.408 135.786 167.057 1.00 128.72 ? 63   PHE A HD2  1 
ATOM   752  H HE1  . PHE A 1 48  ? 172.508 133.857 169.438 1.00 128.66 ? 63   PHE A HE1  1 
ATOM   753  H HE2  . PHE A 1 48  ? 176.587 135.217 169.471 1.00 128.67 ? 63   PHE A HE2  1 
ATOM   754  H HZ   . PHE A 1 48  ? 174.627 134.260 170.665 1.00 128.94 ? 63   PHE A HZ   1 
ATOM   755  N N    . THR A 1 49  ? 173.479 138.271 167.044 1.00 131.69 ? 64   THR A N    1 
ATOM   756  C CA   . THR A 1 49  ? 173.979 139.361 167.887 1.00 130.07 ? 64   THR A CA   1 
ATOM   757  C C    . THR A 1 49  ? 174.648 138.782 169.119 1.00 136.08 ? 64   THR A C    1 
ATOM   758  O O    . THR A 1 49  ? 174.030 138.021 169.857 1.00 137.63 ? 64   THR A O    1 
ATOM   759  C CB   . THR A 1 49  ? 172.854 140.312 168.279 1.00 132.48 ? 64   THR A CB   1 
ATOM   760  O OG1  . THR A 1 49  ? 172.294 140.872 167.117 1.00 140.70 ? 64   THR A OG1  1 
ATOM   761  C CG2  . THR A 1 49  ? 173.334 141.479 169.132 1.00 133.24 ? 64   THR A CG2  1 
ATOM   762  H H    . THR A 1 49  ? 172.773 137.659 167.426 1.00 133.33 ? 64   THR A H    1 
ATOM   763  H HA   . THR A 1 49  ? 174.718 139.943 167.337 1.00 133.18 ? 64   THR A HA   1 
ATOM   764  H HB   . THR A 1 49  ? 172.083 139.767 168.822 1.00 133.82 ? 64   THR A HB   1 
ATOM   765  H HG1  . THR A 1 49  ? 171.821 140.170 166.665 1.00 134.94 ? 64   THR A HG1  1 
ATOM   766  H HG21 . THR A 1 49  ? 172.497 142.145 169.337 1.00 134.23 ? 64   THR A HG21 1 
ATOM   767  H HG22 . THR A 1 49  ? 174.110 142.033 168.605 1.00 133.63 ? 64   THR A HG22 1 
ATOM   768  H HG23 . THR A 1 49  ? 173.727 141.113 170.081 1.00 133.46 ? 64   THR A HG23 1 
ATOM   769  N N    . GLY A 1 50  ? 175.898 139.152 169.371 1.00 131.80 ? 65   GLY A N    1 
ATOM   770  C CA   . GLY A 1 50  ? 176.713 138.577 170.440 1.00 130.72 ? 65   GLY A CA   1 
ATOM   771  C C    . GLY A 1 50  ? 177.783 139.542 170.931 1.00 129.65 ? 65   GLY A C    1 
ATOM   772  O O    . GLY A 1 50  ? 177.897 140.661 170.432 1.00 131.44 ? 65   GLY A O    1 
ATOM   773  H H    . GLY A 1 50  ? 176.336 139.828 168.762 1.00 131.14 ? 65   GLY A H    1 
ATOM   774  H HA2  . GLY A 1 50  ? 176.087 138.301 171.288 1.00 131.40 ? 65   GLY A HA2  1 
ATOM   775  H HA3  . GLY A 1 50  ? 177.208 137.679 170.069 1.00 131.01 ? 65   GLY A HA3  1 
ATOM   776  N N    . TYR A 1 51  ? 178.555 139.136 171.933 1.00 135.48 ? 66   TYR A N    1 
ATOM   777  C CA   . TYR A 1 51  ? 179.704 139.912 172.380 1.00 136.15 ? 66   TYR A CA   1 
ATOM   778  C C    . TYR A 1 51  ? 180.876 139.649 171.445 1.00 138.97 ? 66   TYR A C    1 
ATOM   779  O O    . TYR A 1 51  ? 181.535 138.621 171.557 1.00 143.04 ? 66   TYR A O    1 
ATOM   780  C CB   . TYR A 1 51  ? 180.031 139.578 173.835 1.00 138.64 ? 66   TYR A CB   1 
ATOM   781  C CG   . TYR A 1 51  ? 178.980 140.107 174.780 1.00 140.36 ? 66   TYR A CG   1 
ATOM   782  C CD1  . TYR A 1 51  ? 179.015 141.456 175.170 1.00 140.42 ? 66   TYR A CD1  1 
ATOM   783  C CD2  . TYR A 1 51  ? 177.945 139.271 175.216 1.00 139.38 ? 66   TYR A CD2  1 
ATOM   784  C CE1  . TYR A 1 51  ? 178.017 141.968 176.012 1.00 138.79 ? 66   TYR A CE1  1 
ATOM   785  C CE2  . TYR A 1 51  ? 176.948 139.777 176.061 1.00 139.50 ? 66   TYR A CE2  1 
ATOM   786  C CZ   . TYR A 1 51  ? 176.987 141.124 176.466 1.00 142.30 ? 66   TYR A CZ   1 
ATOM   787  O OH   . TYR A 1 51  ? 176.014 141.624 177.262 1.00 149.81 ? 66   TYR A OH   1 
ATOM   788  H H    . TYR A 1 51  ? 178.440 138.199 172.291 1.00 138.55 ? 66   TYR A H    1 
ATOM   789  H HA   . TYR A 1 51  ? 179.464 140.975 172.336 1.00 138.68 ? 66   TYR A HA   1 
ATOM   790  H HB2  . TYR A 1 51  ? 180.130 138.499 173.955 1.00 138.71 ? 66   TYR A HB2  1 
ATOM   791  H HB3  . TYR A 1 51  ? 180.986 140.033 174.097 1.00 139.50 ? 66   TYR A HB3  1 
ATOM   792  H HD1  . TYR A 1 51  ? 179.808 142.100 174.819 1.00 139.56 ? 66   TYR A HD1  1 
ATOM   793  H HD2  . TYR A 1 51  ? 177.920 138.235 174.911 1.00 139.24 ? 66   TYR A HD2  1 
ATOM   794  H HE1  . TYR A 1 51  ? 178.029 143.005 176.316 1.00 138.93 ? 66   TYR A HE1  1 
ATOM   795  H HE2  . TYR A 1 51  ? 176.156 139.127 176.406 1.00 139.60 ? 66   TYR A HE2  1 
ATOM   796  H HH   . TYR A 1 51  ? 175.383 140.937 177.488 1.00 140.84 ? 66   TYR A HH   1 
ATOM   797  N N    . PHE A 1 52  ? 181.157 140.573 170.531 1.00 128.26 ? 67   PHE A N    1 
ATOM   798  C CA   . PHE A 1 52  ? 182.176 140.401 169.498 1.00 121.44 ? 67   PHE A CA   1 
ATOM   799  C C    . PHE A 1 52  ? 183.127 141.594 169.421 1.00 122.72 ? 67   PHE A C    1 
ATOM   800  O O    . PHE A 1 52  ? 182.761 142.693 169.838 1.00 129.13 ? 67   PHE A O    1 
ATOM   801  C CB   . PHE A 1 52  ? 181.495 140.182 168.149 1.00 122.70 ? 67   PHE A CB   1 
ATOM   802  C CG   . PHE A 1 52  ? 180.620 138.953 168.044 1.00 122.43 ? 67   PHE A CG   1 
ATOM   803  C CD1  . PHE A 1 52  ? 181.101 137.710 168.484 1.00 126.77 ? 67   PHE A CD1  1 
ATOM   804  C CD2  . PHE A 1 52  ? 179.358 139.028 167.440 1.00 123.85 ? 67   PHE A CD2  1 
ATOM   805  C CE1  . PHE A 1 52  ? 180.329 136.553 168.319 1.00 129.20 ? 67   PHE A CE1  1 
ATOM   806  C CE2  . PHE A 1 52  ? 178.589 137.867 167.265 1.00 121.61 ? 67   PHE A CE2  1 
ATOM   807  C CZ   . PHE A 1 52  ? 179.080 136.627 167.695 1.00 123.63 ? 67   PHE A CZ   1 
ATOM   808  H H    . PHE A 1 52  ? 180.604 141.416 170.514 1.00 127.62 ? 67   PHE A H    1 
ATOM   809  H HA   . PHE A 1 52  ? 182.773 139.519 169.728 1.00 125.39 ? 67   PHE A HA   1 
ATOM   810  H HB2  . PHE A 1 52  ? 180.906 141.067 167.908 1.00 126.60 ? 67   PHE A HB2  1 
ATOM   811  H HB3  . PHE A 1 52  ? 182.272 140.087 167.391 1.00 125.32 ? 67   PHE A HB3  1 
ATOM   812  H HD1  . PHE A 1 52  ? 182.073 137.632 168.948 1.00 127.00 ? 67   PHE A HD1  1 
ATOM   813  H HD2  . PHE A 1 52  ? 178.978 139.977 167.091 1.00 127.23 ? 67   PHE A HD2  1 
ATOM   814  H HE1  . PHE A 1 52  ? 180.699 135.602 168.670 1.00 126.95 ? 67   PHE A HE1  1 
ATOM   815  H HE2  . PHE A 1 52  ? 177.621 137.932 166.791 1.00 126.70 ? 67   PHE A HE2  1 
ATOM   816  H HZ   . PHE A 1 52  ? 178.504 135.724 167.555 1.00 126.60 ? 67   PHE A HZ   1 
ATOM   817  N N    . PRO A 1 53  ? 184.351 141.421 168.900 1.00 117.12 ? 68   PRO A N    1 
ATOM   818  C CA   . PRO A 1 53  ? 185.221 142.532 168.565 1.00 116.01 ? 68   PRO A CA   1 
ATOM   819  C C    . PRO A 1 53  ? 184.573 143.457 167.545 1.00 121.21 ? 68   PRO A C    1 
ATOM   820  O O    . PRO A 1 53  ? 183.749 143.021 166.745 1.00 130.64 ? 68   PRO A O    1 
ATOM   821  C CB   . PRO A 1 53  ? 186.471 141.913 167.953 1.00 118.90 ? 68   PRO A CB   1 
ATOM   822  C CG   . PRO A 1 53  ? 186.473 140.499 168.500 1.00 126.49 ? 68   PRO A CG   1 
ATOM   823  C CD   . PRO A 1 53  ? 184.988 140.172 168.553 1.00 123.11 ? 68   PRO A CD   1 
ATOM   824  H HA   . PRO A 1 53  ? 185.479 143.082 169.470 1.00 122.35 ? 68   PRO A HA   1 
ATOM   825  H HB2  . PRO A 1 53  ? 186.371 141.862 166.869 1.00 123.29 ? 68   PRO A HB2  1 
ATOM   826  H HB3  . PRO A 1 53  ? 187.373 142.458 168.231 1.00 122.72 ? 68   PRO A HB3  1 
ATOM   827  H HG2  . PRO A 1 53  ? 187.023 139.816 167.854 1.00 124.32 ? 68   PRO A HG2  1 
ATOM   828  H HG3  . PRO A 1 53  ? 186.886 140.498 169.509 1.00 124.26 ? 68   PRO A HG3  1 
ATOM   829  H HD2  . PRO A 1 53  ? 184.645 139.842 167.572 1.00 123.20 ? 68   PRO A HD2  1 
ATOM   830  H HD3  . PRO A 1 53  ? 184.812 139.399 169.301 1.00 124.06 ? 68   PRO A HD3  1 
ATOM   831  N N    . LYS A 1 54  ? 184.986 144.717 167.500 1.00 128.54 ? 69   LYS A N    1 
ATOM   832  C CA   . LYS A 1 54  ? 184.720 145.578 166.350 1.00 132.96 ? 69   LYS A CA   1 
ATOM   833  C C    . LYS A 1 54  ? 185.724 145.258 165.247 1.00 133.03 ? 69   LYS A C    1 
ATOM   834  O O    . LYS A 1 54  ? 186.923 145.405 165.457 1.00 141.11 ? 69   LYS A O    1 
ATOM   835  C CB   . LYS A 1 54  ? 184.787 147.031 166.818 1.00 132.30 ? 69   LYS A CB   1 
ATOM   836  C CG   . LYS A 1 54  ? 184.491 148.022 165.686 1.00 130.80 ? 69   LYS A CG   1 
ATOM   837  C CD   . LYS A 1 54  ? 184.625 149.483 166.124 1.00 139.53 ? 69   LYS A CD   1 
ATOM   838  C CE   . LYS A 1 54  ? 183.633 149.848 167.230 1.00 141.01 ? 69   LYS A CE   1 
ATOM   839  N NZ   . LYS A 1 54  ? 183.734 151.283 167.590 1.00 145.84 ? 69   LYS A NZ   1 
ATOM   840  H H    . LYS A 1 54  ? 185.669 145.022 168.178 1.00 134.37 ? 69   LYS A H    1 
ATOM   841  H HA   . LYS A 1 54  ? 183.720 145.383 165.962 1.00 135.76 ? 69   LYS A HA   1 
ATOM   842  H HB2  . LYS A 1 54  ? 184.051 147.166 167.610 1.00 134.71 ? 69   LYS A HB2  1 
ATOM   843  H HB3  . LYS A 1 54  ? 185.774 147.235 167.233 1.00 135.45 ? 69   LYS A HB3  1 
ATOM   844  H HG2  . LYS A 1 54  ? 185.195 147.857 164.870 1.00 134.53 ? 69   LYS A HG2  1 
ATOM   845  H HG3  . LYS A 1 54  ? 183.482 147.850 165.309 1.00 134.75 ? 69   LYS A HG3  1 
ATOM   846  H HD2  . LYS A 1 54  ? 185.644 149.658 166.471 1.00 136.25 ? 69   LYS A HD2  1 
ATOM   847  H HD3  . LYS A 1 54  ? 184.445 150.116 165.255 1.00 135.99 ? 69   LYS A HD3  1 
ATOM   848  H HE2  . LYS A 1 54  ? 182.624 149.622 166.885 1.00 135.73 ? 69   LYS A HE2  1 
ATOM   849  H HE3  . LYS A 1 54  ? 183.838 149.235 168.107 1.00 135.54 ? 69   LYS A HE3  1 
ATOM   850  H HZ1  . LYS A 1 54  ? 183.082 151.523 168.322 1.00 136.50 ? 69   LYS A HZ1  1 
ATOM   851  H HZ2  . LYS A 1 54  ? 184.663 151.512 167.916 1.00 136.62 ? 69   LYS A HZ2  1 
ATOM   852  H HZ3  . LYS A 1 54  ? 183.533 151.872 166.794 1.00 136.90 ? 69   LYS A HZ3  1 
ATOM   853  N N    . SER A 1 55  ? 185.277 144.837 164.073 1.00 129.79 ? 70   SER A N    1 
ATOM   854  C CA   . SER A 1 55  ? 186.191 144.624 162.946 1.00 131.92 ? 70   SER A CA   1 
ATOM   855  C C    . SER A 1 55  ? 186.914 145.917 162.581 1.00 129.28 ? 70   SER A C    1 
ATOM   856  O O    . SER A 1 55  ? 186.320 146.991 162.616 1.00 132.03 ? 70   SER A O    1 
ATOM   857  C CB   . SER A 1 55  ? 185.432 144.097 161.739 1.00 137.90 ? 70   SER A CB   1 
ATOM   858  O OG   . SER A 1 55  ? 186.336 143.848 160.686 1.00 139.60 ? 70   SER A OG   1 
ATOM   859  H H    . SER A 1 55  ? 184.280 144.742 163.941 1.00 133.95 ? 70   SER A H    1 
ATOM   860  H HA   . SER A 1 55  ? 186.934 143.879 163.232 1.00 133.92 ? 70   SER A HA   1 
ATOM   861  H HB2  . SER A 1 55  ? 184.921 143.172 162.007 1.00 134.53 ? 70   SER A HB2  1 
ATOM   862  H HB3  . SER A 1 55  ? 184.700 144.840 161.425 1.00 134.17 ? 70   SER A HB3  1 
ATOM   863  H HG   . SER A 1 55  ? 185.840 143.747 159.870 1.00 134.47 ? 70   SER A HG   1 
ATOM   864  N N    . GLY A 1 56  ? 188.204 145.858 162.262 1.00 130.51 ? 71   GLY A N    1 
ATOM   865  C CA   . GLY A 1 56  ? 189.003 147.053 161.990 1.00 135.34 ? 71   GLY A CA   1 
ATOM   866  C C    . GLY A 1 56  ? 189.393 147.880 163.224 1.00 135.76 ? 71   GLY A C    1 
ATOM   867  O O    . GLY A 1 56  ? 190.108 148.869 163.077 1.00 133.02 ? 71   GLY A O    1 
ATOM   868  H H    . GLY A 1 56  ? 188.656 144.958 162.186 1.00 132.95 ? 71   GLY A H    1 
ATOM   869  H HA2  . GLY A 1 56  ? 189.922 146.744 161.492 1.00 132.86 ? 71   GLY A HA2  1 
ATOM   870  H HA3  . GLY A 1 56  ? 188.456 147.703 161.306 1.00 133.57 ? 71   GLY A HA3  1 
ATOM   871  N N    . ALA A 1 57  ? 188.984 147.503 164.438 1.00 138.89 ? 72   ALA A N    1 
ATOM   872  C CA   . ALA A 1 57  ? 189.622 148.002 165.654 1.00 137.22 ? 72   ALA A CA   1 
ATOM   873  C C    . ALA A 1 57  ? 191.018 147.398 165.826 1.00 138.41 ? 72   ALA A C    1 
ATOM   874  O O    . ALA A 1 57  ? 191.351 146.386 165.212 1.00 141.45 ? 72   ALA A O    1 
ATOM   875  C CB   . ALA A 1 57  ? 188.750 147.674 166.865 1.00 134.70 ? 72   ALA A CB   1 
ATOM   876  H H    . ALA A 1 57  ? 188.381 146.697 164.524 1.00 136.61 ? 72   ALA A H    1 
ATOM   877  H HA   . ALA A 1 57  ? 189.722 149.085 165.590 1.00 136.33 ? 72   ALA A HA   1 
ATOM   878  H HB1  . ALA A 1 57  ? 187.762 148.112 166.724 1.00 136.17 ? 72   ALA A HB1  1 
ATOM   879  H HB2  . ALA A 1 57  ? 188.665 146.594 166.987 1.00 136.86 ? 72   ALA A HB2  1 
ATOM   880  H HB3  . ALA A 1 57  ? 189.192 148.097 167.767 1.00 136.03 ? 72   ALA A HB3  1 
ATOM   881  N N    . ASN A 1 58  ? 191.818 147.975 166.713 1.00 137.22 ? 73   ASN A N    1 
ATOM   882  C CA   . ASN A 1 58  ? 193.132 147.440 167.025 1.00 136.99 ? 73   ASN A CA   1 
ATOM   883  C C    . ASN A 1 58  ? 193.086 146.403 168.151 1.00 137.89 ? 73   ASN A C    1 
ATOM   884  O O    . ASN A 1 58  ? 192.351 146.531 169.129 1.00 137.56 ? 73   ASN A O    1 
ATOM   885  C CB   . ASN A 1 58  ? 194.111 148.584 167.314 1.00 136.07 ? 73   ASN A CB   1 
ATOM   886  C CG   . ASN A 1 58  ? 194.451 149.399 166.081 1.00 142.69 ? 73   ASN A CG   1 
ATOM   887  O OD1  . ASN A 1 58  ? 193.872 149.267 165.015 1.00 141.97 ? 73   ASN A OD1  1 
ATOM   888  N ND2  . ASN A 1 58  ? 195.422 150.268 166.173 1.00 143.05 ? 73   ASN A ND2  1 
ATOM   889  H H    . ASN A 1 58  ? 191.496 148.790 167.213 1.00 137.99 ? 73   ASN A H    1 
ATOM   890  H HA   . ASN A 1 58  ? 193.505 146.926 166.140 1.00 137.67 ? 73   ASN A HA   1 
ATOM   891  H HB2  . ASN A 1 58  ? 193.706 149.241 168.081 1.00 137.34 ? 73   ASN A HB2  1 
ATOM   892  H HB3  . ASN A 1 58  ? 195.042 148.161 167.688 1.00 137.96 ? 73   ASN A HB3  1 
ATOM   893  H HD21 . ASN A 1 58  ? 195.911 150.393 167.046 1.00 138.59 ? 73   ASN A HD21 1 
ATOM   894  H HD22 . ASN A 1 58  ? 195.663 150.813 165.360 1.00 138.33 ? 73   ASN A HD22 1 
ATOM   895  N N    . PHE A 1 59  ? 193.928 145.386 168.028 1.00 129.12 ? 74   PHE A N    1 
ATOM   896  C CA   . PHE A 1 59  ? 194.484 144.645 169.138 1.00 123.49 ? 74   PHE A CA   1 
ATOM   897  C C    . PHE A 1 59  ? 195.668 145.402 169.733 1.00 132.10 ? 74   PHE A C    1 
ATOM   898  O O    . PHE A 1 59  ? 196.445 146.013 169.000 1.00 135.42 ? 74   PHE A O    1 
ATOM   899  C CB   . PHE A 1 59  ? 195.033 143.318 168.636 1.00 124.05 ? 74   PHE A CB   1 
ATOM   900  C CG   . PHE A 1 59  ? 194.026 142.243 168.344 1.00 121.05 ? 74   PHE A CG   1 
ATOM   901  C CD1  . PHE A 1 59  ? 193.444 141.543 169.407 1.00 121.49 ? 74   PHE A CD1  1 
ATOM   902  C CD2  . PHE A 1 59  ? 193.778 141.841 167.025 1.00 129.81 ? 74   PHE A CD2  1 
ATOM   903  C CE1  . PHE A 1 59  ? 192.634 140.432 169.163 1.00 125.49 ? 74   PHE A CE1  1 
ATOM   904  C CE2  . PHE A 1 59  ? 192.981 140.718 166.779 1.00 131.26 ? 74   PHE A CE2  1 
ATOM   905  C CZ   . PHE A 1 59  ? 192.417 140.013 167.848 1.00 126.46 ? 74   PHE A CZ   1 
ATOM   906  H H    . PHE A 1 59  ? 194.459 145.353 167.170 1.00 130.32 ? 74   PHE A H    1 
ATOM   907  H HA   . PHE A 1 59  ? 193.728 144.470 169.902 1.00 128.09 ? 74   PHE A HA   1 
ATOM   908  H HB2  . PHE A 1 59  ? 195.652 143.489 167.757 1.00 129.62 ? 74   PHE A HB2  1 
ATOM   909  H HB3  . PHE A 1 59  ? 195.688 142.927 169.414 1.00 128.23 ? 74   PHE A HB3  1 
ATOM   910  H HD1  . PHE A 1 59  ? 193.651 141.839 170.425 1.00 128.60 ? 74   PHE A HD1  1 
ATOM   911  H HD2  . PHE A 1 59  ? 194.225 142.373 166.199 1.00 129.69 ? 74   PHE A HD2  1 
ATOM   912  H HE1  . PHE A 1 59  ? 192.203 139.887 169.988 1.00 129.32 ? 74   PHE A HE1  1 
ATOM   913  H HE2  . PHE A 1 59  ? 192.813 140.388 165.765 1.00 129.83 ? 74   PHE A HE2  1 
ATOM   914  H HZ   . PHE A 1 59  ? 191.814 139.139 167.656 1.00 128.84 ? 74   PHE A HZ   1 
ATOM   915  N N    . ARG A 1 60  ? 195.875 145.269 171.041 1.00 136.80 ? 75   ARG A N    1 
ATOM   916  C CA   . ARG A 1 60  ? 197.074 145.711 171.759 1.00 131.72 ? 75   ARG A CA   1 
ATOM   917  C C    . ARG A 1 60  ? 197.822 144.497 172.286 1.00 135.49 ? 75   ARG A C    1 
ATOM   918  O O    . ARG A 1 60  ? 197.207 143.682 172.963 1.00 146.55 ? 75   ARG A O    1 
ATOM   919  C CB   . ARG A 1 60  ? 196.618 146.610 172.911 1.00 131.40 ? 75   ARG A CB   1 
ATOM   920  C CG   . ARG A 1 60  ? 196.124 147.976 172.417 1.00 129.71 ? 75   ARG A CG   1 
ATOM   921  C CD   . ARG A 1 60  ? 195.094 148.607 173.360 1.00 134.63 ? 75   ARG A CD   1 
ATOM   922  N NE   . ARG A 1 60  ? 195.595 148.791 174.738 1.00 139.13 ? 75   ARG A NE   1 
ATOM   923  C CZ   . ARG A 1 60  ? 194.974 148.448 175.854 1.00 140.72 ? 75   ARG A CZ   1 
ATOM   924  N NH1  . ARG A 1 60  ? 195.478 148.727 177.013 1.00 140.75 ? 75   ARG A NH1  1 
ATOM   925  N NH2  . ARG A 1 60  ? 193.833 147.827 175.853 1.00 138.24 ? 75   ARG A NH2  1 
ATOM   926  H H    . ARG A 1 60  ? 195.172 144.773 171.570 1.00 136.91 ? 75   ARG A H    1 
ATOM   927  H HA   . ARG A 1 60  ? 197.746 146.270 171.108 1.00 136.35 ? 75   ARG A HA   1 
ATOM   928  H HB2  . ARG A 1 60  ? 195.818 146.106 173.452 1.00 136.46 ? 75   ARG A HB2  1 
ATOM   929  H HB3  . ARG A 1 60  ? 197.442 146.761 173.608 1.00 136.79 ? 75   ARG A HB3  1 
ATOM   930  H HG2  . ARG A 1 60  ? 196.970 148.652 172.296 1.00 136.28 ? 75   ARG A HG2  1 
ATOM   931  H HG3  . ARG A 1 60  ? 195.652 147.869 171.441 1.00 136.29 ? 75   ARG A HG3  1 
ATOM   932  H HD2  . ARG A 1 60  ? 194.815 149.578 172.954 1.00 136.78 ? 75   ARG A HD2  1 
ATOM   933  H HD3  . ARG A 1 60  ? 194.204 147.978 173.346 1.00 136.96 ? 75   ARG A HD3  1 
ATOM   934  H HE   . ARG A 1 60  ? 196.461 149.295 174.850 1.00 136.72 ? 75   ARG A HE   1 
ATOM   935  H HH11 . ARG A 1 60  ? 196.329 149.261 177.112 1.00 137.53 ? 75   ARG A HH11 1 
ATOM   936  H HH12 . ARG A 1 60  ? 195.027 148.413 177.860 1.00 136.84 ? 75   ARG A HH12 1 
ATOM   937  H HH21 . ARG A 1 60  ? 193.372 147.662 174.972 1.00 137.43 ? 75   ARG A HH21 1 
ATOM   938  H HH22 . ARG A 1 60  ? 193.357 147.650 176.725 1.00 136.58 ? 75   ARG A HH22 1 
ATOM   939  N N    . ASP A 1 61  ? 199.111 144.344 172.005 1.00 131.40 ? 76   ASP A N    1 
ATOM   940  C CA   . ASP A 1 61  ? 199.914 143.293 172.639 1.00 133.62 ? 76   ASP A CA   1 
ATOM   941  C C    . ASP A 1 61  ? 200.343 143.729 174.033 1.00 142.18 ? 76   ASP A C    1 
ATOM   942  O O    . ASP A 1 61  ? 201.259 144.532 174.183 1.00 137.65 ? 76   ASP A O    1 
ATOM   943  C CB   . ASP A 1 61  ? 201.147 142.943 171.809 1.00 131.88 ? 76   ASP A CB   1 
ATOM   944  C CG   . ASP A 1 61  ? 202.042 141.905 172.492 1.00 142.67 ? 76   ASP A CG   1 
ATOM   945  O OD1  . ASP A 1 61  ? 201.592 141.200 173.425 1.00 156.05 ? 76   ASP A OD1  1 
ATOM   946  O OD2  . ASP A 1 61  ? 203.211 141.783 172.073 1.00 141.43 ? 76   ASP A OD2  1 
ATOM   947  H H    . ASP A 1 61  ? 199.578 145.027 171.427 1.00 138.35 ? 76   ASP A H    1 
ATOM   948  H HA   . ASP A 1 61  ? 199.314 142.387 172.728 1.00 138.68 ? 76   ASP A HA   1 
ATOM   949  H HB2  . ASP A 1 61  ? 200.828 142.530 170.853 1.00 137.61 ? 76   ASP A HB2  1 
ATOM   950  H HB3  . ASP A 1 61  ? 201.717 143.851 171.619 1.00 137.76 ? 76   ASP A HB3  1 
ATOM   951  N N    . LEU A 1 62  ? 199.692 143.199 175.060 1.00 139.38 ? 77   LEU A N    1 
ATOM   952  C CA   . LEU A 1 62  ? 199.990 143.542 176.445 1.00 130.05 ? 77   LEU A CA   1 
ATOM   953  C C    . LEU A 1 62  ? 201.025 142.625 177.093 1.00 130.77 ? 77   LEU A C    1 
ATOM   954  O O    . LEU A 1 62  ? 201.318 142.787 178.272 1.00 137.02 ? 77   LEU A O    1 
ATOM   955  C CB   . LEU A 1 62  ? 198.698 143.560 177.259 1.00 128.56 ? 77   LEU A CB   1 
ATOM   956  C CG   . LEU A 1 62  ? 197.624 144.508 176.733 1.00 125.53 ? 77   LEU A CG   1 
ATOM   957  C CD1  . LEU A 1 62  ? 196.509 144.572 177.762 1.00 129.98 ? 77   LEU A CD1  1 
ATOM   958  C CD2  . LEU A 1 62  ? 198.142 145.920 176.518 1.00 130.94 ? 77   LEU A CD2  1 
ATOM   959  H H    . LEU A 1 62  ? 198.974 142.518 174.868 1.00 133.61 ? 77   LEU A H    1 
ATOM   960  H HA   . LEU A 1 62  ? 200.424 144.541 176.480 1.00 131.93 ? 77   LEU A HA   1 
ATOM   961  H HB2  . LEU A 1 62  ? 198.292 142.550 177.291 1.00 132.13 ? 77   LEU A HB2  1 
ATOM   962  H HB3  . LEU A 1 62  ? 198.943 143.856 178.279 1.00 132.29 ? 77   LEU A HB3  1 
ATOM   963  H HG   . LEU A 1 62  ? 197.227 144.129 175.792 1.00 132.04 ? 77   LEU A HG   1 
ATOM   964  H HD11 . LEU A 1 62  ? 196.131 143.566 177.936 1.00 132.79 ? 77   LEU A HD11 1 
ATOM   965  H HD12 . LEU A 1 62  ? 196.884 144.980 178.699 1.00 133.09 ? 77   LEU A HD12 1 
ATOM   966  H HD13 . LEU A 1 62  ? 195.706 145.211 177.396 1.00 131.78 ? 77   LEU A HD13 1 
ATOM   967  H HD21 . LEU A 1 62  ? 197.315 146.581 176.267 1.00 132.81 ? 77   LEU A HD21 1 
ATOM   968  H HD22 . LEU A 1 62  ? 198.633 146.281 177.420 1.00 132.38 ? 77   LEU A HD22 1 
ATOM   969  H HD23 . LEU A 1 62  ? 198.848 145.929 175.689 1.00 132.97 ? 77   LEU A HD23 1 
ATOM   970  N N    . SER A 1 63  ? 201.584 141.649 176.388 1.00 137.26 ? 78   SER A N    1 
ATOM   971  C CA   . SER A 1 63  ? 202.590 140.781 176.997 1.00 135.19 ? 78   SER A CA   1 
ATOM   972  C C    . SER A 1 63  ? 203.867 141.555 177.318 1.00 130.79 ? 78   SER A C    1 
ATOM   973  O O    . SER A 1 63  ? 204.363 142.326 176.501 1.00 128.01 ? 78   SER A O    1 
ATOM   974  C CB   . SER A 1 63  ? 202.882 139.585 176.099 1.00 142.88 ? 78   SER A CB   1 
ATOM   975  O OG   . SER A 1 63  ? 203.428 139.973 174.863 1.00 151.73 ? 78   SER A OG   1 
ATOM   976  H H    . SER A 1 63  ? 201.401 141.570 175.398 1.00 138.73 ? 78   SER A H    1 
ATOM   977  H HA   . SER A 1 63  ? 202.183 140.389 177.929 1.00 137.45 ? 78   SER A HA   1 
ATOM   978  H HB2  . SER A 1 63  ? 203.586 138.927 176.610 1.00 138.22 ? 78   SER A HB2  1 
ATOM   979  H HB3  . SER A 1 63  ? 201.960 139.034 175.917 1.00 137.89 ? 78   SER A HB3  1 
ATOM   980  H HG   . SER A 1 63  ? 202.760 140.422 174.342 1.00 140.26 ? 78   SER A HG   1 
ATOM   981  N N    . LEU A 1 64  ? 204.410 141.355 178.517 1.00 133.10 ? 79   LEU A N    1 
ATOM   982  C CA   . LEU A 1 64  ? 205.683 141.928 178.949 1.00 130.66 ? 79   LEU A CA   1 
ATOM   983  C C    . LEU A 1 64  ? 206.632 140.817 179.379 1.00 137.63 ? 79   LEU A C    1 
ATOM   984  O O    . LEU A 1 64  ? 206.317 140.054 180.291 1.00 142.29 ? 79   LEU A O    1 
ATOM   985  C CB   . LEU A 1 64  ? 205.439 142.905 180.105 1.00 134.15 ? 79   LEU A CB   1 
ATOM   986  C CG   . LEU A 1 64  ? 204.775 144.218 179.678 1.00 139.63 ? 79   LEU A CG   1 
ATOM   987  C CD1  . LEU A 1 64  ? 204.329 144.957 180.930 1.00 139.53 ? 79   LEU A CD1  1 
ATOM   988  C CD2  . LEU A 1 64  ? 205.751 145.113 178.920 1.00 144.03 ? 79   LEU A CD2  1 
ATOM   989  H H    . LEU A 1 64  ? 203.946 140.727 179.156 1.00 138.96 ? 79   LEU A H    1 
ATOM   990  H HA   . LEU A 1 64  ? 206.159 142.466 178.130 1.00 137.99 ? 79   LEU A HA   1 
ATOM   991  H HB2  . LEU A 1 64  ? 204.806 142.417 180.844 1.00 138.65 ? 79   LEU A HB2  1 
ATOM   992  H HB3  . LEU A 1 64  ? 206.388 143.136 180.587 1.00 138.66 ? 79   LEU A HB3  1 
ATOM   993  H HG   . LEU A 1 64  ? 203.901 144.025 179.058 1.00 138.96 ? 79   LEU A HG   1 
ATOM   994  H HD11 . LEU A 1 64  ? 203.546 144.389 181.430 1.00 139.52 ? 79   LEU A HD11 1 
ATOM   995  H HD12 . LEU A 1 64  ? 203.935 145.938 180.668 1.00 138.87 ? 79   LEU A HD12 1 
ATOM   996  H HD13 . LEU A 1 64  ? 205.179 145.075 181.600 1.00 138.75 ? 79   LEU A HD13 1 
ATOM   997  H HD21 . LEU A 1 64  ? 205.278 146.067 178.697 1.00 139.86 ? 79   LEU A HD21 1 
ATOM   998  H HD22 . LEU A 1 64  ? 206.636 145.296 179.524 1.00 139.39 ? 79   LEU A HD22 1 
ATOM   999  H HD23 . LEU A 1 64  ? 206.041 144.649 177.980 1.00 139.89 ? 79   LEU A HD23 1 
ATOM   1000 N N    . LYS A 1 65  ? 207.806 140.736 178.757 1.00 155.06 ? 80   LYS A N    1 
ATOM   1001 C CA   . LYS A 1 65  ? 208.860 139.794 179.156 1.00 152.45 ? 80   LYS A CA   1 
ATOM   1002 C C    . LYS A 1 65  ? 209.946 140.564 179.894 1.00 151.84 ? 80   LYS A C    1 
ATOM   1003 O O    . LYS A 1 65  ? 210.505 141.509 179.347 1.00 154.56 ? 80   LYS A O    1 
ATOM   1004 C CB   . LYS A 1 65  ? 209.410 139.041 177.930 1.00 153.18 ? 80   LYS A CB   1 
ATOM   1005 C CG   . LYS A 1 65  ? 210.370 137.904 178.311 1.00 153.53 ? 80   LYS A CG   1 
ATOM   1006 C CD   . LYS A 1 65  ? 211.840 138.336 178.422 1.00 157.16 ? 80   LYS A CD   1 
ATOM   1007 C CE   . LYS A 1 65  ? 212.636 137.154 178.970 1.00 159.79 ? 80   LYS A CE   1 
ATOM   1008 N NZ   . LYS A 1 65  ? 214.088 137.438 179.103 1.00 159.13 ? 80   LYS A NZ   1 
ATOM   1009 H H    . LYS A 1 65  ? 208.012 141.394 178.019 1.00 156.16 ? 80   LYS A H    1 
ATOM   1010 H HA   . LYS A 1 65  ? 208.440 139.054 179.836 1.00 155.94 ? 80   LYS A HA   1 
ATOM   1011 H HB2  . LYS A 1 65  ? 208.568 138.597 177.399 1.00 156.20 ? 80   LYS A HB2  1 
ATOM   1012 H HB3  . LYS A 1 65  ? 209.904 139.732 177.245 1.00 156.13 ? 80   LYS A HB3  1 
ATOM   1013 H HG2  . LYS A 1 65  ? 210.040 137.459 179.249 1.00 156.19 ? 80   LYS A HG2  1 
ATOM   1014 H HG3  . LYS A 1 65  ? 210.305 137.137 177.539 1.00 155.98 ? 80   LYS A HG3  1 
ATOM   1015 H HD2  . LYS A 1 65  ? 212.209 138.616 177.435 1.00 156.38 ? 80   LYS A HD2  1 
ATOM   1016 H HD3  . LYS A 1 65  ? 211.955 139.183 179.097 1.00 156.62 ? 80   LYS A HD3  1 
ATOM   1017 H HE2  . LYS A 1 65  ? 212.224 136.893 179.945 1.00 157.33 ? 80   LYS A HE2  1 
ATOM   1018 H HE3  . LYS A 1 65  ? 212.489 136.304 178.302 1.00 156.55 ? 80   LYS A HE3  1 
ATOM   1019 H HZ1  . LYS A 1 65  ? 214.268 138.233 179.699 1.00 157.13 ? 80   LYS A HZ1  1 
ATOM   1020 H HZ2  . LYS A 1 65  ? 214.544 136.646 179.534 1.00 156.81 ? 80   LYS A HZ2  1 
ATOM   1021 H HZ3  . LYS A 1 65  ? 214.513 137.591 178.200 1.00 156.19 ? 80   LYS A HZ3  1 
ATOM   1022 N N    . GLY A 1 66  ? 210.276 140.142 181.107 1.00 153.61 ? 81   GLY A N    1 
ATOM   1023 C CA   . GLY A 1 66  ? 211.393 140.683 181.890 1.00 152.95 ? 81   GLY A CA   1 
ATOM   1024 C C    . GLY A 1 66  ? 212.510 139.661 182.102 1.00 160.36 ? 81   GLY A C    1 
ATOM   1025 O O    . GLY A 1 66  ? 212.349 138.478 181.796 1.00 168.41 ? 81   GLY A O    1 
ATOM   1026 H H    . GLY A 1 66  ? 209.765 139.353 181.478 1.00 158.46 ? 81   GLY A H    1 
ATOM   1027 H HA2  . GLY A 1 66  ? 211.823 141.555 181.396 1.00 157.53 ? 81   GLY A HA2  1 
ATOM   1028 H HA3  . GLY A 1 66  ? 211.029 141.004 182.866 1.00 157.73 ? 81   GLY A HA3  1 
ATOM   1029 N N    . THR A 1 67  ? 213.633 140.091 182.670 1.00 169.10 ? 82   THR A N    1 
ATOM   1030 C CA   . THR A 1 67  ? 214.750 139.194 183.023 1.00 171.94 ? 82   THR A CA   1 
ATOM   1031 C C    . THR A 1 67  ? 215.127 139.292 184.502 1.00 170.98 ? 82   THR A C    1 
ATOM   1032 O O    . THR A 1 67  ? 215.192 138.271 185.184 1.00 175.70 ? 82   THR A O    1 
ATOM   1033 C CB   . THR A 1 67  ? 215.976 139.440 182.133 1.00 172.59 ? 82   THR A CB   1 
ATOM   1034 O OG1  . THR A 1 67  ? 215.638 139.279 180.772 1.00 174.89 ? 82   THR A OG1  1 
ATOM   1035 C CG2  . THR A 1 67  ? 217.114 138.460 182.410 1.00 170.16 ? 82   THR A CG2  1 
ATOM   1036 H H    . THR A 1 67  ? 213.717 141.081 182.853 1.00 169.96 ? 82   THR A H    1 
ATOM   1037 H HA   . THR A 1 67  ? 214.455 138.158 182.859 1.00 170.99 ? 82   THR A HA   1 
ATOM   1038 H HB   . THR A 1 67  ? 216.335 140.457 182.287 1.00 170.85 ? 82   THR A HB   1 
ATOM   1039 H HG1  . THR A 1 67  ? 216.364 139.664 180.275 1.00 171.24 ? 82   THR A HG1  1 
ATOM   1040 H HG21 . THR A 1 67  ? 217.922 138.619 181.697 1.00 170.83 ? 82   THR A HG21 1 
ATOM   1041 H HG22 . THR A 1 67  ? 216.753 137.435 182.322 1.00 170.35 ? 82   THR A HG22 1 
ATOM   1042 H HG23 . THR A 1 67  ? 217.512 138.616 183.413 1.00 170.80 ? 82   THR A HG23 1 
ATOM   1043 N N    . THR A 1 68  ? 215.272 140.514 185.030 1.00 172.42 ? 83   THR A N    1 
ATOM   1044 C CA   . THR A 1 68  ? 215.583 140.789 186.447 1.00 177.21 ? 83   THR A CA   1 
ATOM   1045 C C    . THR A 1 68  ? 214.815 141.989 186.983 1.00 175.22 ? 83   THR A C    1 
ATOM   1046 O O    . THR A 1 68  ? 214.006 141.836 187.899 1.00 177.29 ? 83   THR A O    1 
ATOM   1047 C CB   . THR A 1 68  ? 217.094 140.981 186.672 1.00 176.00 ? 83   THR A CB   1 
ATOM   1048 O OG1  . THR A 1 68  ? 217.798 139.835 186.267 1.00 180.17 ? 83   THR A OG1  1 
ATOM   1049 C CG2  . THR A 1 68  ? 217.457 141.228 188.132 1.00 173.74 ? 83   THR A CG2  1 
ATOM   1050 H H    . THR A 1 68  ? 215.174 141.306 184.411 1.00 174.08 ? 83   THR A H    1 
ATOM   1051 H HA   . THR A 1 68  ? 215.259 139.945 187.056 1.00 175.53 ? 83   THR A HA   1 
ATOM   1052 H HB   . THR A 1 68  ? 217.444 141.824 186.077 1.00 174.41 ? 83   THR A HB   1 
ATOM   1053 H HG1  . THR A 1 68  ? 217.470 139.110 186.802 1.00 175.77 ? 83   THR A HG1  1 
ATOM   1054 H HG21 . THR A 1 68  ? 217.051 140.437 188.761 1.00 175.12 ? 83   THR A HG21 1 
ATOM   1055 H HG22 . THR A 1 68  ? 218.541 141.252 188.241 1.00 174.49 ? 83   THR A HG22 1 
ATOM   1056 H HG23 . THR A 1 68  ? 217.067 142.190 188.461 1.00 174.38 ? 83   THR A HG23 1 
ATOM   1057 N N    . TYR A 1 69  ? 215.039 143.182 186.432 1.00 162.81 ? 84   TYR A N    1 
ATOM   1058 C CA   . TYR A 1 69  ? 214.368 144.396 186.884 1.00 163.32 ? 84   TYR A CA   1 
ATOM   1059 C C    . TYR A 1 69  ? 212.925 144.483 186.403 1.00 166.01 ? 84   TYR A C    1 
ATOM   1060 O O    . TYR A 1 69  ? 212.627 144.135 185.264 1.00 169.94 ? 84   TYR A O    1 
ATOM   1061 C CB   . TYR A 1 69  ? 215.143 145.633 186.436 1.00 159.47 ? 84   TYR A CB   1 
ATOM   1062 C CG   . TYR A 1 69  ? 216.403 145.850 187.236 1.00 165.45 ? 84   TYR A CG   1 
ATOM   1063 C CD1  . TYR A 1 69  ? 217.610 145.242 186.844 1.00 167.65 ? 84   TYR A CD1  1 
ATOM   1064 C CD2  . TYR A 1 69  ? 216.354 146.626 188.405 1.00 167.51 ? 84   TYR A CD2  1 
ATOM   1065 C CE1  . TYR A 1 69  ? 218.758 145.393 187.639 1.00 169.18 ? 84   TYR A CE1  1 
ATOM   1066 C CE2  . TYR A 1 69  ? 217.502 146.784 189.200 1.00 167.67 ? 84   TYR A CE2  1 
ATOM   1067 C CZ   . TYR A 1 69  ? 218.706 146.156 188.820 1.00 168.07 ? 84   TYR A CZ   1 
ATOM   1068 O OH   . TYR A 1 69  ? 219.812 146.285 189.594 1.00 167.00 ? 84   TYR A OH   1 
ATOM   1069 H H    . TYR A 1 69  ? 215.698 143.263 185.672 1.00 165.49 ? 84   TYR A H    1 
ATOM   1070 H HA   . TYR A 1 69  ? 214.358 144.390 187.974 1.00 166.32 ? 84   TYR A HA   1 
ATOM   1071 H HB2  . TYR A 1 69  ? 215.386 145.554 185.377 1.00 165.07 ? 84   TYR A HB2  1 
ATOM   1072 H HB3  . TYR A 1 69  ? 214.502 146.505 186.561 1.00 165.10 ? 84   TYR A HB3  1 
ATOM   1073 H HD1  . TYR A 1 69  ? 217.654 144.657 185.938 1.00 165.94 ? 84   TYR A HD1  1 
ATOM   1074 H HD2  . TYR A 1 69  ? 215.428 147.089 188.710 1.00 166.03 ? 84   TYR A HD2  1 
ATOM   1075 H HE1  . TYR A 1 69  ? 219.686 144.925 187.348 1.00 166.40 ? 84   TYR A HE1  1 
ATOM   1076 H HE2  . TYR A 1 69  ? 217.465 147.374 190.103 1.00 166.12 ? 84   TYR A HE2  1 
ATOM   1077 H HH   . TYR A 1 69  ? 219.649 146.849 190.351 1.00 166.42 ? 84   TYR A HH   1 
ATOM   1078 N N    . LEU A 1 70  ? 212.039 145.004 187.252 1.00 162.46 ? 85   LEU A N    1 
ATOM   1079 C CA   . LEU A 1 70  ? 210.657 145.341 186.910 1.00 157.98 ? 85   LEU A CA   1 
ATOM   1080 C C    . LEU A 1 70  ? 210.483 146.858 186.862 1.00 163.08 ? 85   LEU A C    1 
ATOM   1081 O O    . LEU A 1 70  ? 210.844 147.548 187.812 1.00 167.25 ? 85   LEU A O    1 
ATOM   1082 C CB   . LEU A 1 70  ? 209.704 144.741 187.953 1.00 157.18 ? 85   LEU A CB   1 
ATOM   1083 C CG   . LEU A 1 70  ? 209.738 143.211 188.051 1.00 160.41 ? 85   LEU A CG   1 
ATOM   1084 C CD1  . LEU A 1 70  ? 208.842 142.751 189.193 1.00 162.60 ? 85   LEU A CD1  1 
ATOM   1085 C CD2  . LEU A 1 70  ? 209.257 142.554 186.764 1.00 161.75 ? 85   LEU A CD2  1 
ATOM   1086 H H    . LEU A 1 70  ? 212.369 145.257 188.171 1.00 162.17 ? 85   LEU A H    1 
ATOM   1087 H HA   . LEU A 1 70  ? 210.401 144.943 185.928 1.00 160.48 ? 85   LEU A HA   1 
ATOM   1088 H HB2  . LEU A 1 70  ? 209.963 145.153 188.927 1.00 161.00 ? 85   LEU A HB2  1 
ATOM   1089 H HB3  . LEU A 1 70  ? 208.687 145.055 187.719 1.00 160.66 ? 85   LEU A HB3  1 
ATOM   1090 H HG   . LEU A 1 70  ? 210.754 142.878 188.260 1.00 161.10 ? 85   LEU A HG   1 
ATOM   1091 H HD11 . LEU A 1 70  ? 208.911 141.669 189.295 1.00 161.26 ? 85   LEU A HD11 1 
ATOM   1092 H HD12 . LEU A 1 70  ? 207.808 143.030 188.995 1.00 161.58 ? 85   LEU A HD12 1 
ATOM   1093 H HD13 . LEU A 1 70  ? 209.165 143.214 190.123 1.00 161.13 ? 85   LEU A HD13 1 
ATOM   1094 H HD21 . LEU A 1 70  ? 209.976 142.742 185.968 1.00 161.09 ? 85   LEU A HD21 1 
ATOM   1095 H HD22 . LEU A 1 70  ? 208.281 142.948 186.484 1.00 161.04 ? 85   LEU A HD22 1 
ATOM   1096 H HD23 . LEU A 1 70  ? 209.180 141.477 186.908 1.00 162.07 ? 85   LEU A HD23 1 
ATOM   1097 N N    . SER A 1 71  ? 209.911 147.390 185.786 1.00 165.32 ? 86   SER A N    1 
ATOM   1098 C CA   . SER A 1 71  ? 209.538 148.805 185.763 1.00 167.59 ? 86   SER A CA   1 
ATOM   1099 C C    . SER A 1 71  ? 208.243 149.046 186.531 1.00 166.18 ? 86   SER A C    1 
ATOM   1100 O O    . SER A 1 71  ? 207.236 148.395 186.268 1.00 163.60 ? 86   SER A O    1 
ATOM   1101 C CB   . SER A 1 71  ? 209.378 149.325 184.340 1.00 167.72 ? 86   SER A CB   1 
ATOM   1102 O OG   . SER A 1 71  ? 208.985 150.682 184.388 1.00 168.35 ? 86   SER A OG   1 
ATOM   1103 H H    . SER A 1 71  ? 209.606 146.787 185.037 1.00 164.75 ? 86   SER A H    1 
ATOM   1104 H HA   . SER A 1 71  ? 210.339 149.385 186.222 1.00 165.62 ? 86   SER A HA   1 
ATOM   1105 H HB2  . SER A 1 71  ? 210.325 149.233 183.809 1.00 165.72 ? 86   SER A HB2  1 
ATOM   1106 H HB3  . SER A 1 71  ? 208.614 148.747 183.822 1.00 165.44 ? 86   SER A HB3  1 
ATOM   1107 H HG   . SER A 1 71  ? 209.393 151.126 183.642 1.00 166.24 ? 86   SER A HG   1 
ATOM   1108 N N    . THR A 1 72  ? 208.207 150.034 187.418 1.00 156.97 ? 87   THR A N    1 
ATOM   1109 C CA   . THR A 1 72  ? 206.955 150.481 188.041 1.00 153.42 ? 87   THR A CA   1 
ATOM   1110 C C    . THR A 1 72  ? 205.922 150.908 187.007 1.00 152.81 ? 87   THR A C    1 
ATOM   1111 O O    . THR A 1 72  ? 204.727 150.734 187.223 1.00 153.19 ? 87   THR A O    1 
ATOM   1112 C CB   . THR A 1 72  ? 207.199 151.667 188.971 1.00 154.29 ? 87   THR A CB   1 
ATOM   1113 O OG1  . THR A 1 72  ? 207.808 152.713 188.258 1.00 157.60 ? 87   THR A OG1  1 
ATOM   1114 C CG2  . THR A 1 72  ? 208.085 151.307 190.152 1.00 153.79 ? 87   THR A CG2  1 
ATOM   1115 H H    . THR A 1 72  ? 209.051 150.554 187.603 1.00 156.81 ? 87   THR A H    1 
ATOM   1116 H HA   . THR A 1 72  ? 206.530 149.664 188.624 1.00 155.73 ? 87   THR A HA   1 
ATOM   1117 H HB   . THR A 1 72  ? 206.242 152.013 189.358 1.00 155.41 ? 87   THR A HB   1 
ATOM   1118 H HG1  . THR A 1 72  ? 208.622 152.951 188.707 1.00 157.06 ? 87   THR A HG1  1 
ATOM   1119 H HG21 . THR A 1 72  ? 208.147 152.155 190.829 1.00 156.18 ? 87   THR A HG21 1 
ATOM   1120 H HG22 . THR A 1 72  ? 207.661 150.459 190.683 1.00 155.15 ? 87   THR A HG22 1 
ATOM   1121 H HG23 . THR A 1 72  ? 209.086 151.053 189.811 1.00 155.97 ? 87   THR A HG23 1 
ATOM   1122 N N    . LEU A 1 73  ? 206.350 151.416 185.853 1.00 150.40 ? 88   LEU A N    1 
ATOM   1123 C CA   . LEU A 1 73  ? 205.461 151.919 184.813 1.00 152.23 ? 88   LEU A CA   1 
ATOM   1124 C C    . LEU A 1 73  ? 204.682 150.808 184.108 1.00 151.79 ? 88   LEU A C    1 
ATOM   1125 O O    . LEU A 1 73  ? 203.669 151.084 183.478 1.00 155.65 ? 88   LEU A O    1 
ATOM   1126 C CB   . LEU A 1 73  ? 206.267 152.759 183.813 1.00 149.09 ? 88   LEU A CB   1 
ATOM   1127 C CG   . LEU A 1 73  ? 206.963 153.970 184.455 1.00 151.85 ? 88   LEU A CG   1 
ATOM   1128 C CD1  . LEU A 1 73  ? 207.853 154.647 183.426 1.00 154.46 ? 88   LEU A CD1  1 
ATOM   1129 C CD2  . LEU A 1 73  ? 205.958 155.003 184.959 1.00 153.44 ? 88   LEU A CD2  1 
ATOM   1130 H H    . LEU A 1 73  ? 207.347 151.482 185.712 1.00 153.74 ? 88   LEU A H    1 
ATOM   1131 H HA   . LEU A 1 73  ? 204.714 152.562 185.275 1.00 154.10 ? 88   LEU A HA   1 
ATOM   1132 H HB2  . LEU A 1 73  ? 207.016 152.130 183.335 1.00 153.73 ? 88   LEU A HB2  1 
ATOM   1133 H HB3  . LEU A 1 73  ? 205.591 153.116 183.037 1.00 153.10 ? 88   LEU A HB3  1 
ATOM   1134 H HG   . LEU A 1 73  ? 207.597 153.651 185.281 1.00 153.84 ? 88   LEU A HG   1 
ATOM   1135 H HD11 . LEU A 1 73  ? 208.348 155.509 183.871 1.00 155.01 ? 88   LEU A HD11 1 
ATOM   1136 H HD12 . LEU A 1 73  ? 207.261 154.968 182.571 1.00 154.70 ? 88   LEU A HD12 1 
ATOM   1137 H HD13 . LEU A 1 73  ? 208.621 153.948 183.102 1.00 154.94 ? 88   LEU A HD13 1 
ATOM   1138 H HD21 . LEU A 1 73  ? 205.384 154.590 185.785 1.00 153.40 ? 88   LEU A HD21 1 
ATOM   1139 H HD22 . LEU A 1 73  ? 206.486 155.883 185.322 1.00 154.02 ? 88   LEU A HD22 1 
ATOM   1140 H HD23 . LEU A 1 73  ? 205.284 155.294 184.156 1.00 153.52 ? 88   LEU A HD23 1 
ATOM   1141 N N    . TRP A 1 74  ? 205.089 149.548 184.243 1.00 144.54 ? 89   TRP A N    1 
ATOM   1142 C CA   . TRP A 1 74  ? 204.318 148.414 183.736 1.00 146.67 ? 89   TRP A CA   1 
ATOM   1143 C C    . TRP A 1 74  ? 203.042 148.155 184.532 1.00 146.66 ? 89   TRP A C    1 
ATOM   1144 O O    . TRP A 1 74  ? 202.181 147.413 184.077 1.00 151.70 ? 89   TRP A O    1 
ATOM   1145 C CB   . TRP A 1 74  ? 205.192 147.164 183.767 1.00 148.57 ? 89   TRP A CB   1 
ATOM   1146 C CG   . TRP A 1 74  ? 206.404 147.189 182.899 1.00 145.19 ? 89   TRP A CG   1 
ATOM   1147 C CD1  . TRP A 1 74  ? 206.659 148.069 181.907 1.00 148.51 ? 89   TRP A CD1  1 
ATOM   1148 C CD2  . TRP A 1 74  ? 207.506 146.245 182.881 1.00 142.05 ? 89   TRP A CD2  1 
ATOM   1149 N NE1  . TRP A 1 74  ? 207.848 147.747 181.294 1.00 147.29 ? 89   TRP A NE1  1 
ATOM   1150 C CE2  . TRP A 1 74  ? 208.409 146.623 181.850 1.00 145.04 ? 89   TRP A CE2  1 
ATOM   1151 C CE3  . TRP A 1 74  ? 207.825 145.099 183.631 1.00 142.26 ? 89   TRP A CE3  1 
ATOM   1152 C CZ2  . TRP A 1 74  ? 209.572 145.904 181.573 1.00 147.59 ? 89   TRP A CZ2  1 
ATOM   1153 C CZ3  . TRP A 1 74  ? 208.982 144.355 183.350 1.00 146.25 ? 89   TRP A CZ3  1 
ATOM   1154 C CH2  . TRP A 1 74  ? 209.856 144.756 182.329 1.00 149.79 ? 89   TRP A CH2  1 
ATOM   1155 H H    . TRP A 1 74  ? 205.928 149.365 184.772 1.00 147.72 ? 89   TRP A H    1 
ATOM   1156 H HA   . TRP A 1 74  ? 204.015 148.603 182.706 1.00 147.62 ? 89   TRP A HA   1 
ATOM   1157 H HB2  . TRP A 1 74  ? 205.507 146.975 184.792 1.00 148.20 ? 89   TRP A HB2  1 
ATOM   1158 H HB3  . TRP A 1 74  ? 204.583 146.314 183.460 1.00 147.75 ? 89   TRP A HB3  1 
ATOM   1159 H HD1  . TRP A 1 74  ? 206.021 148.890 181.619 1.00 148.21 ? 89   TRP A HD1  1 
ATOM   1160 H HE1  . TRP A 1 74  ? 208.202 148.258 180.500 1.00 148.37 ? 89   TRP A HE1  1 
ATOM   1161 H HE3  . TRP A 1 74  ? 207.159 144.783 184.420 1.00 146.99 ? 89   TRP A HE3  1 
ATOM   1162 H HZ2  . TRP A 1 74  ? 210.234 146.223 180.782 1.00 147.78 ? 89   TRP A HZ2  1 
ATOM   1163 H HZ3  . TRP A 1 74  ? 209.203 143.464 183.919 1.00 147.64 ? 89   TRP A HZ3  1 
ATOM   1164 H HH2  . TRP A 1 74  ? 210.745 144.180 182.122 1.00 148.26 ? 89   TRP A HH2  1 
ATOM   1165 N N    . TYR A 1 75  ? 202.905 148.737 185.720 1.00 144.69 ? 90   TYR A N    1 
ATOM   1166 C CA   . TYR A 1 75  ? 201.805 148.481 186.647 1.00 145.68 ? 90   TYR A CA   1 
ATOM   1167 C C    . TYR A 1 75  ? 200.853 149.672 186.752 1.00 147.45 ? 90   TYR A C    1 
ATOM   1168 O O    . TYR A 1 75  ? 200.360 150.012 187.829 1.00 151.17 ? 90   TYR A O    1 
ATOM   1169 C CB   . TYR A 1 75  ? 202.400 148.042 187.982 1.00 145.92 ? 90   TYR A CB   1 
ATOM   1170 C CG   . TYR A 1 75  ? 203.209 146.778 187.864 1.00 140.91 ? 90   TYR A CG   1 
ATOM   1171 C CD1  . TYR A 1 75  ? 202.544 145.568 187.664 1.00 138.83 ? 90   TYR A CD1  1 
ATOM   1172 C CD2  . TYR A 1 75  ? 204.610 146.810 187.928 1.00 143.94 ? 90   TYR A CD2  1 
ATOM   1173 C CE1  . TYR A 1 75  ? 203.265 144.375 187.581 1.00 143.45 ? 90   TYR A CE1  1 
ATOM   1174 C CE2  . TYR A 1 75  ? 205.339 145.612 187.853 1.00 144.04 ? 90   TYR A CE2  1 
ATOM   1175 C CZ   . TYR A 1 75  ? 204.663 144.391 187.694 1.00 147.94 ? 90   TYR A CZ   1 
ATOM   1176 O OH   . TYR A 1 75  ? 205.339 143.222 187.665 1.00 155.85 ? 90   TYR A OH   1 
ATOM   1177 H H    . TYR A 1 75  ? 203.656 149.329 186.042 1.00 146.75 ? 90   TYR A H    1 
ATOM   1178 H HA   . TYR A 1 75  ? 201.203 147.653 186.274 1.00 146.52 ? 90   TYR A HA   1 
ATOM   1179 H HB2  . TYR A 1 75  ? 203.026 148.840 188.380 1.00 147.23 ? 90   TYR A HB2  1 
ATOM   1180 H HB3  . TYR A 1 75  ? 201.592 147.860 188.689 1.00 146.92 ? 90   TYR A HB3  1 
ATOM   1181 H HD1  . TYR A 1 75  ? 201.471 145.550 187.545 1.00 146.07 ? 90   TYR A HD1  1 
ATOM   1182 H HD2  . TYR A 1 75  ? 205.126 147.750 188.051 1.00 147.15 ? 90   TYR A HD2  1 
ATOM   1183 H HE1  . TYR A 1 75  ? 202.747 143.443 187.412 1.00 146.90 ? 90   TYR A HE1  1 
ATOM   1184 H HE2  . TYR A 1 75  ? 206.415 145.628 187.927 1.00 146.82 ? 90   TYR A HE2  1 
ATOM   1185 H HH   . TYR A 1 75  ? 204.732 142.483 187.750 1.00 147.83 ? 90   TYR A HH   1 
ATOM   1186 N N    . GLN A 1 76  ? 200.633 150.341 185.626 1.00 146.16 ? 91   GLN A N    1 
ATOM   1187 C CA   . GLN A 1 76  ? 199.855 151.568 185.481 1.00 143.27 ? 91   GLN A CA   1 
ATOM   1188 C C    . GLN A 1 76  ? 199.128 151.556 184.132 1.00 148.03 ? 91   GLN A C    1 
ATOM   1189 O O    . GLN A 1 76  ? 199.361 150.674 183.302 1.00 154.98 ? 91   GLN A O    1 
ATOM   1190 C CB   . GLN A 1 76  ? 200.790 152.783 185.567 1.00 139.04 ? 91   GLN A CB   1 
ATOM   1191 C CG   . GLN A 1 76  ? 201.569 152.873 186.885 1.00 144.54 ? 91   GLN A CG   1 
ATOM   1192 C CD   . GLN A 1 76  ? 202.296 154.198 187.072 1.00 150.55 ? 91   GLN A CD   1 
ATOM   1193 O OE1  . GLN A 1 76  ? 202.092 155.174 186.365 1.00 153.48 ? 91   GLN A OE1  1 
ATOM   1194 N NE2  . GLN A 1 76  ? 203.169 154.293 188.048 1.00 150.98 ? 91   GLN A NE2  1 
ATOM   1195 H H    . GLN A 1 76  ? 201.039 149.972 184.778 1.00 147.62 ? 91   GLN A H    1 
ATOM   1196 H HA   . GLN A 1 76  ? 199.106 151.635 186.271 1.00 146.84 ? 91   GLN A HA   1 
ATOM   1197 H HB2  . GLN A 1 76  ? 201.500 152.754 184.739 1.00 146.22 ? 91   GLN A HB2  1 
ATOM   1198 H HB3  . GLN A 1 76  ? 200.182 153.681 185.464 1.00 145.94 ? 91   GLN A HB3  1 
ATOM   1199 H HG2  . GLN A 1 76  ? 200.874 152.754 187.717 1.00 146.79 ? 91   GLN A HG2  1 
ATOM   1200 H HG3  . GLN A 1 76  ? 202.305 152.069 186.926 1.00 147.16 ? 91   GLN A HG3  1 
ATOM   1201 H HE21 . GLN A 1 76  ? 203.367 153.499 188.640 1.00 147.37 ? 91   GLN A HE21 1 
ATOM   1202 H HE22 . GLN A 1 76  ? 203.648 155.173 188.174 1.00 147.93 ? 91   GLN A HE22 1 
ATOM   1203 N N    . LYS A 1 77  ? 198.254 152.527 183.858 1.00 150.06 ? 92   LYS A N    1 
ATOM   1204 C CA   . LYS A 1 77  ? 197.829 152.780 182.473 1.00 150.35 ? 92   LYS A CA   1 
ATOM   1205 C C    . LYS A 1 77  ? 199.069 153.086 181.616 1.00 152.96 ? 92   LYS A C    1 
ATOM   1206 O O    . LYS A 1 77  ? 199.980 153.748 182.111 1.00 153.08 ? 92   LYS A O    1 
ATOM   1207 C CB   . LYS A 1 77  ? 196.818 153.931 182.413 1.00 150.06 ? 92   LYS A CB   1 
ATOM   1208 C CG   . LYS A 1 77  ? 195.482 153.533 183.056 1.00 155.24 ? 92   LYS A CG   1 
ATOM   1209 C CD   . LYS A 1 77  ? 194.369 154.562 182.831 1.00 158.58 ? 92   LYS A CD   1 
ATOM   1210 C CE   . LYS A 1 77  ? 194.677 155.903 183.503 1.00 160.38 ? 92   LYS A CE   1 
ATOM   1211 N NZ   . LYS A 1 77  ? 193.567 156.866 183.308 1.00 158.56 ? 92   LYS A NZ   1 
ATOM   1212 H H    . LYS A 1 77  ? 198.073 153.230 184.560 1.00 152.06 ? 92   LYS A H    1 
ATOM   1213 H HA   . LYS A 1 77  ? 197.351 151.879 182.086 1.00 152.49 ? 92   LYS A HA   1 
ATOM   1214 H HB2  . LYS A 1 77  ? 197.228 154.807 182.916 1.00 152.49 ? 92   LYS A HB2  1 
ATOM   1215 H HB3  . LYS A 1 77  ? 196.635 154.188 181.370 1.00 152.56 ? 92   LYS A HB3  1 
ATOM   1216 H HG2  . LYS A 1 77  ? 195.151 152.595 182.610 1.00 153.34 ? 92   LYS A HG2  1 
ATOM   1217 H HG3  . LYS A 1 77  ? 195.619 153.379 184.127 1.00 153.21 ? 92   LYS A HG3  1 
ATOM   1218 H HD2  . LYS A 1 77  ? 194.232 154.710 181.759 1.00 153.63 ? 92   LYS A HD2  1 
ATOM   1219 H HD3  . LYS A 1 77  ? 193.445 154.159 183.243 1.00 153.33 ? 92   LYS A HD3  1 
ATOM   1220 H HE2  . LYS A 1 77  ? 194.839 155.731 184.567 1.00 153.95 ? 92   LYS A HE2  1 
ATOM   1221 H HE3  . LYS A 1 77  ? 195.597 156.307 183.082 1.00 153.97 ? 92   LYS A HE3  1 
ATOM   1222 H HZ1  . LYS A 1 77  ? 193.769 157.749 183.754 1.00 153.82 ? 92   LYS A HZ1  1 
ATOM   1223 H HZ2  . LYS A 1 77  ? 192.706 156.512 183.701 1.00 153.55 ? 92   LYS A HZ2  1 
ATOM   1224 H HZ3  . LYS A 1 77  ? 193.409 157.044 182.326 1.00 153.39 ? 92   LYS A HZ3  1 
ATOM   1225 N N    . PRO A 1 78  ? 199.138 152.659 180.347 1.00 143.07 ? 93   PRO A N    1 
ATOM   1226 C CA   . PRO A 1 78  ? 198.078 152.048 179.556 1.00 139.28 ? 93   PRO A CA   1 
ATOM   1227 C C    . PRO A 1 78  ? 197.935 150.529 179.716 1.00 142.13 ? 93   PRO A C    1 
ATOM   1228 O O    . PRO A 1 78  ? 197.084 149.944 179.057 1.00 147.48 ? 93   PRO A O    1 
ATOM   1229 C CB   . PRO A 1 78  ? 198.457 152.395 178.116 1.00 140.80 ? 93   PRO A CB   1 
ATOM   1230 C CG   . PRO A 1 78  ? 199.978 152.313 178.146 1.00 141.25 ? 93   PRO A CG   1 
ATOM   1231 C CD   . PRO A 1 78  ? 200.289 152.931 179.501 1.00 140.14 ? 93   PRO A CD   1 
ATOM   1232 H HA   . PRO A 1 78  ? 197.117 152.503 179.791 1.00 140.91 ? 93   PRO A HA   1 
ATOM   1233 H HB2  . PRO A 1 78  ? 198.029 151.712 177.385 1.00 141.10 ? 93   PRO A HB2  1 
ATOM   1234 H HB3  . PRO A 1 78  ? 198.153 153.418 177.896 1.00 141.87 ? 93   PRO A HB3  1 
ATOM   1235 H HG2  . PRO A 1 78  ? 200.299 151.273 178.128 1.00 141.39 ? 93   PRO A HG2  1 
ATOM   1236 H HG3  . PRO A 1 78  ? 200.433 152.873 177.330 1.00 141.55 ? 93   PRO A HG3  1 
ATOM   1237 H HD2  . PRO A 1 78  ? 201.196 152.494 179.917 1.00 141.04 ? 93   PRO A HD2  1 
ATOM   1238 H HD3  . PRO A 1 78  ? 200.409 154.007 179.388 1.00 141.13 ? 93   PRO A HD3  1 
ATOM   1239 N N    . PHE A 1 79  ? 198.753 149.858 180.526 1.00 136.48 ? 94   PHE A N    1 
ATOM   1240 C CA   . PHE A 1 79  ? 198.705 148.401 180.665 1.00 135.43 ? 94   PHE A CA   1 
ATOM   1241 C C    . PHE A 1 79  ? 197.532 147.935 181.531 1.00 134.69 ? 94   PHE A C    1 
ATOM   1242 O O    . PHE A 1 79  ? 196.733 147.108 181.099 1.00 134.77 ? 94   PHE A O    1 
ATOM   1243 C CB   . PHE A 1 79  ? 200.029 147.886 181.223 1.00 135.92 ? 94   PHE A CB   1 
ATOM   1244 C CG   . PHE A 1 79  ? 201.240 148.265 180.403 1.00 133.08 ? 94   PHE A CG   1 
ATOM   1245 C CD1  . PHE A 1 79  ? 201.693 147.412 179.385 1.00 133.91 ? 94   PHE A CD1  1 
ATOM   1246 C CD2  . PHE A 1 79  ? 201.940 149.448 180.682 1.00 135.89 ? 94   PHE A CD2  1 
ATOM   1247 C CE1  . PHE A 1 79  ? 202.845 147.737 178.657 1.00 135.47 ? 94   PHE A CE1  1 
ATOM   1248 C CE2  . PHE A 1 79  ? 203.085 149.781 179.945 1.00 136.34 ? 94   PHE A CE2  1 
ATOM   1249 C CZ   . PHE A 1 79  ? 203.536 148.926 178.928 1.00 133.29 ? 94   PHE A CZ   1 
ATOM   1250 H H    . PHE A 1 79  ? 199.437 150.364 181.069 1.00 137.26 ? 94   PHE A H    1 
ATOM   1251 H HA   . PHE A 1 79  ? 198.574 147.956 179.679 1.00 136.84 ? 94   PHE A HA   1 
ATOM   1252 H HB2  . PHE A 1 79  ? 200.164 148.263 182.236 1.00 138.11 ? 94   PHE A HB2  1 
ATOM   1253 H HB3  . PHE A 1 79  ? 199.979 146.799 181.279 1.00 136.56 ? 94   PHE A HB3  1 
ATOM   1254 H HD1  . PHE A 1 79  ? 201.167 146.494 179.174 1.00 136.28 ? 94   PHE A HD1  1 
ATOM   1255 H HD2  . PHE A 1 79  ? 201.613 150.101 181.477 1.00 137.47 ? 94   PHE A HD2  1 
ATOM   1256 H HE1  . PHE A 1 79  ? 203.197 147.073 177.882 1.00 137.27 ? 94   PHE A HE1  1 
ATOM   1257 H HE2  . PHE A 1 79  ? 203.619 150.694 180.162 1.00 137.04 ? 94   PHE A HE2  1 
ATOM   1258 H HZ   . PHE A 1 79  ? 204.418 149.179 178.360 1.00 136.48 ? 94   PHE A HZ   1 
ATOM   1259 N N    . LEU A 1 80  ? 197.379 148.487 182.737 1.00 138.82 ? 95   LEU A N    1 
ATOM   1260 C CA   . LEU A 1 80  ? 196.190 148.283 183.560 1.00 139.01 ? 95   LEU A CA   1 
ATOM   1261 C C    . LEU A 1 80  ? 194.989 148.870 182.815 1.00 139.93 ? 95   LEU A C    1 
ATOM   1262 O O    . LEU A 1 80  ? 194.942 150.074 182.585 1.00 145.30 ? 95   LEU A O    1 
ATOM   1263 C CB   . LEU A 1 80  ? 196.428 148.926 184.933 1.00 137.64 ? 95   LEU A CB   1 
ATOM   1264 C CG   . LEU A 1 80  ? 195.203 148.906 185.854 1.00 139.15 ? 95   LEU A CG   1 
ATOM   1265 C CD1  . LEU A 1 80  ? 194.725 147.490 186.143 1.00 146.05 ? 95   LEU A CD1  1 
ATOM   1266 C CD2  . LEU A 1 80  ? 195.560 149.564 187.181 1.00 137.87 ? 95   LEU A CD2  1 
ATOM   1267 H H    . LEU A 1 80  ? 198.060 149.172 183.030 1.00 141.40 ? 95   LEU A H    1 
ATOM   1268 H HA   . LEU A 1 80  ? 196.026 147.214 183.696 1.00 141.10 ? 95   LEU A HA   1 
ATOM   1269 H HB2  . LEU A 1 80  ? 197.252 148.408 185.424 1.00 140.83 ? 95   LEU A HB2  1 
ATOM   1270 H HB3  . LEU A 1 80  ? 196.718 149.966 184.785 1.00 140.73 ? 95   LEU A HB3  1 
ATOM   1271 H HG   . LEU A 1 80  ? 194.388 149.469 185.399 1.00 140.96 ? 95   LEU A HG   1 
ATOM   1272 H HD11 . LEU A 1 80  ? 194.346 147.024 185.233 1.00 142.14 ? 95   LEU A HD11 1 
ATOM   1273 H HD12 . LEU A 1 80  ? 193.918 147.522 186.874 1.00 141.56 ? 95   LEU A HD12 1 
ATOM   1274 H HD13 . LEU A 1 80  ? 195.544 146.892 186.544 1.00 142.33 ? 95   LEU A HD13 1 
ATOM   1275 H HD21 . LEU A 1 80  ? 195.882 150.591 187.006 1.00 140.81 ? 95   LEU A HD21 1 
ATOM   1276 H HD22 . LEU A 1 80  ? 196.361 149.012 187.671 1.00 140.78 ? 95   LEU A HD22 1 
ATOM   1277 H HD23 . LEU A 1 80  ? 194.684 149.580 187.829 1.00 141.30 ? 95   LEU A HD23 1 
ATOM   1278 N N    . SER A 1 81  ? 194.054 148.027 182.390 1.00 135.88 ? 96   SER A N    1 
ATOM   1279 C CA   . SER A 1 81  ? 193.082 148.373 181.349 1.00 138.45 ? 96   SER A CA   1 
ATOM   1280 C C    . SER A 1 81  ? 191.643 148.240 181.825 1.00 139.71 ? 96   SER A C    1 
ATOM   1281 O O    . SER A 1 81  ? 191.333 147.365 182.626 1.00 142.53 ? 96   SER A O    1 
ATOM   1282 C CB   . SER A 1 81  ? 193.290 147.450 180.155 1.00 143.69 ? 96   SER A CB   1 
ATOM   1283 O OG   . SER A 1 81  ? 194.550 147.653 179.554 1.00 139.40 ? 96   SER A OG   1 
ATOM   1284 H H    . SER A 1 81  ? 194.118 147.055 182.656 1.00 139.98 ? 96   SER A H    1 
ATOM   1285 H HA   . SER A 1 81  ? 193.231 149.398 181.010 1.00 139.78 ? 96   SER A HA   1 
ATOM   1286 H HB2  . SER A 1 81  ? 193.221 146.417 180.495 1.00 140.20 ? 96   SER A HB2  1 
ATOM   1287 H HB3  . SER A 1 81  ? 192.510 147.637 179.417 1.00 141.02 ? 96   SER A HB3  1 
ATOM   1288 H HG   . SER A 1 81  ? 195.230 147.385 180.177 1.00 139.58 ? 96   SER A HG   1 
ATOM   1289 N N    . ASP A 1 82  ? 190.746 149.082 181.318 1.00 149.29 ? 97   ASP A N    1 
ATOM   1290 C CA   . ASP A 1 82  ? 189.322 149.026 181.657 1.00 150.06 ? 97   ASP A CA   1 
ATOM   1291 C C    . ASP A 1 82  ? 188.640 147.818 181.003 1.00 148.82 ? 97   ASP A C    1 
ATOM   1292 O O    . ASP A 1 82  ? 188.783 147.601 179.802 1.00 149.17 ? 97   ASP A O    1 
ATOM   1293 C CB   . ASP A 1 82  ? 188.608 150.311 181.218 1.00 155.47 ? 97   ASP A CB   1 
ATOM   1294 C CG   . ASP A 1 82  ? 189.190 151.603 181.804 1.00 162.77 ? 97   ASP A CG   1 
ATOM   1295 O OD1  . ASP A 1 82  ? 189.771 151.581 182.912 1.00 162.41 ? 97   ASP A OD1  1 
ATOM   1296 O OD2  . ASP A 1 82  ? 189.043 152.663 181.154 1.00 166.36 ? 97   ASP A OD2  1 
ATOM   1297 H H    . ASP A 1 82  ? 191.051 149.775 180.651 1.00 152.89 ? 97   ASP A H    1 
ATOM   1298 H HA   . ASP A 1 82  ? 189.223 148.938 182.739 1.00 153.22 ? 97   ASP A HA   1 
ATOM   1299 H HB2  . ASP A 1 82  ? 188.640 150.372 180.130 1.00 153.97 ? 97   ASP A HB2  1 
ATOM   1300 H HB3  . ASP A 1 82  ? 187.561 150.239 181.515 1.00 153.31 ? 97   ASP A HB3  1 
ATOM   1301 N N    . PHE A 1 83  ? 187.874 147.037 181.764 1.00 134.82 ? 98   PHE A N    1 
ATOM   1302 C CA   . PHE A 1 83  ? 187.259 145.803 181.267 1.00 136.20 ? 98   PHE A CA   1 
ATOM   1303 C C    . PHE A 1 83  ? 185.927 146.017 180.533 1.00 139.46 ? 98   PHE A C    1 
ATOM   1304 O O    . PHE A 1 83  ? 185.636 145.294 179.586 1.00 141.91 ? 98   PHE A O    1 
ATOM   1305 C CB   . PHE A 1 83  ? 187.107 144.836 182.439 1.00 133.37 ? 98   PHE A CB   1 
ATOM   1306 C CG   . PHE A 1 83  ? 186.614 143.462 182.053 1.00 128.11 ? 98   PHE A CG   1 
ATOM   1307 C CD1  . PHE A 1 83  ? 187.465 142.567 181.386 1.00 128.43 ? 98   PHE A CD1  1 
ATOM   1308 C CD2  . PHE A 1 83  ? 185.313 143.060 182.385 1.00 132.20 ? 98   PHE A CD2  1 
ATOM   1309 C CE1  . PHE A 1 83  ? 187.023 141.276 181.069 1.00 133.01 ? 98   PHE A CE1  1 
ATOM   1310 C CE2  . PHE A 1 83  ? 184.869 141.768 182.068 1.00 134.32 ? 98   PHE A CE2  1 
ATOM   1311 C CZ   . PHE A 1 83  ? 185.725 140.874 181.410 1.00 135.40 ? 98   PHE A CZ   1 
ATOM   1312 H H    . PHE A 1 83  ? 187.785 147.268 182.743 1.00 135.90 ? 98   PHE A H    1 
ATOM   1313 H HA   . PHE A 1 83  ? 187.935 145.341 180.547 1.00 136.01 ? 98   PHE A HA   1 
ATOM   1314 H HB2  . PHE A 1 83  ? 188.074 144.719 182.929 1.00 135.55 ? 98   PHE A HB2  1 
ATOM   1315 H HB3  . PHE A 1 83  ? 186.423 145.269 183.169 1.00 135.16 ? 98   PHE A HB3  1 
ATOM   1316 H HD1  . PHE A 1 83  ? 188.470 142.865 181.125 1.00 135.32 ? 98   PHE A HD1  1 
ATOM   1317 H HD2  . PHE A 1 83  ? 184.654 143.743 182.900 1.00 135.39 ? 98   PHE A HD2  1 
ATOM   1318 H HE1  . PHE A 1 83  ? 187.686 140.586 180.570 1.00 135.57 ? 98   PHE A HE1  1 
ATOM   1319 H HE2  . PHE A 1 83  ? 183.870 141.458 182.336 1.00 135.18 ? 98   PHE A HE2  1 
ATOM   1320 H HZ   . PHE A 1 83  ? 185.383 139.880 181.165 1.00 135.38 ? 98   PHE A HZ   1 
ATOM   1321 N N    . ASN A 1 84  ? 185.127 147.018 180.915 1.00 140.80 ? 99   ASN A N    1 
ATOM   1322 C CA   . ASN A 1 84  ? 183.834 147.333 180.290 1.00 136.31 ? 99   ASN A CA   1 
ATOM   1323 C C    . ASN A 1 84  ? 182.941 146.085 180.123 1.00 141.36 ? 99   ASN A C    1 
ATOM   1324 O O    . ASN A 1 84  ? 182.694 145.377 181.097 1.00 149.37 ? 99   ASN A O    1 
ATOM   1325 C CB   . ASN A 1 84  ? 184.061 148.149 179.003 1.00 136.43 ? 99   ASN A CB   1 
ATOM   1326 C CG   . ASN A 1 84  ? 184.767 149.466 179.256 1.00 145.41 ? 99   ASN A CG   1 
ATOM   1327 O OD1  . ASN A 1 84  ? 184.712 150.037 180.334 1.00 149.24 ? 99   ASN A OD1  1 
ATOM   1328 N ND2  . ASN A 1 84  ? 185.433 150.005 178.265 1.00 145.85 ? 99   ASN A ND2  1 
ATOM   1329 H H    . ASN A 1 84  ? 185.432 147.601 181.681 1.00 141.98 ? 99   ASN A H    1 
ATOM   1330 H HA   . ASN A 1 84  ? 183.284 147.976 180.978 1.00 141.69 ? 99   ASN A HA   1 
ATOM   1331 H HB2  . ASN A 1 84  ? 184.651 147.562 178.299 1.00 141.71 ? 99   ASN A HB2  1 
ATOM   1332 H HB3  . ASN A 1 84  ? 183.103 148.388 178.542 1.00 141.38 ? 99   ASN A HB3  1 
ATOM   1333 H HD21 . ASN A 1 84  ? 185.476 149.545 177.367 1.00 142.71 ? 99   ASN A HD21 1 
ATOM   1334 H HD22 . ASN A 1 84  ? 185.897 150.888 178.426 1.00 142.96 ? 99   ASN A HD22 1 
ATOM   1335 N N    . ASN A 1 85  ? 182.431 145.797 178.923 1.00 135.97 ? 100  ASN A N    1 
ATOM   1336 C CA   . ASN A 1 85  ? 181.646 144.587 178.679 1.00 139.20 ? 100  ASN A CA   1 
ATOM   1337 C C    . ASN A 1 85  ? 182.499 143.318 178.661 1.00 140.65 ? 100  ASN A C    1 
ATOM   1338 O O    . ASN A 1 85  ? 182.011 142.259 179.044 1.00 143.65 ? 100  ASN A O    1 
ATOM   1339 C CB   . ASN A 1 85  ? 180.903 144.719 177.347 1.00 139.39 ? 100  ASN A CB   1 
ATOM   1340 C CG   . ASN A 1 85  ? 179.952 145.892 177.326 1.00 146.15 ? 100  ASN A CG   1 
ATOM   1341 O OD1  . ASN A 1 85  ? 180.211 146.918 176.718 1.00 149.62 ? 100  ASN A OD1  1 
ATOM   1342 N ND2  . ASN A 1 85  ? 178.830 145.793 177.995 1.00 146.33 ? 100  ASN A ND2  1 
ATOM   1343 H H    . ASN A 1 85  ? 182.622 146.417 178.149 1.00 139.80 ? 100  ASN A H    1 
ATOM   1344 H HA   . ASN A 1 85  ? 180.912 144.470 179.475 1.00 141.15 ? 100  ASN A HA   1 
ATOM   1345 H HB2  . ASN A 1 85  ? 181.621 144.836 176.534 1.00 140.35 ? 100  ASN A HB2  1 
ATOM   1346 H HB3  . ASN A 1 85  ? 180.332 143.808 177.167 1.00 140.73 ? 100  ASN A HB3  1 
ATOM   1347 H HD21 . ASN A 1 85  ? 178.609 144.951 178.508 1.00 141.43 ? 100  ASN A HD21 1 
ATOM   1348 H HD22 . ASN A 1 85  ? 178.204 146.586 177.996 1.00 141.96 ? 100  ASN A HD22 1 
ATOM   1349 N N    . GLY A 1 86  ? 183.745 143.394 178.199 1.00 128.32 ? 101  GLY A N    1 
ATOM   1350 C CA   . GLY A 1 86  ? 184.626 142.241 178.055 1.00 129.78 ? 101  GLY A CA   1 
ATOM   1351 C C    . GLY A 1 86  ? 185.775 142.466 177.079 1.00 128.07 ? 101  GLY A C    1 
ATOM   1352 O O    . GLY A 1 86  ? 185.912 143.537 176.488 1.00 127.81 ? 101  GLY A O    1 
ATOM   1353 H H    . GLY A 1 86  ? 184.127 144.301 177.967 1.00 129.95 ? 101  GLY A H    1 
ATOM   1354 H HA2  . GLY A 1 86  ? 185.044 141.983 179.028 1.00 129.99 ? 101  GLY A HA2  1 
ATOM   1355 H HA3  . GLY A 1 86  ? 184.046 141.393 177.693 1.00 130.94 ? 101  GLY A HA3  1 
ATOM   1356 N N    . ILE A 1 87  ? 186.571 141.426 176.855 1.00 128.89 ? 102  ILE A N    1 
ATOM   1357 C CA   . ILE A 1 87  ? 187.719 141.414 175.953 1.00 129.76 ? 102  ILE A CA   1 
ATOM   1358 C C    . ILE A 1 87  ? 187.807 140.107 175.174 1.00 129.04 ? 102  ILE A C    1 
ATOM   1359 O O    . ILE A 1 87  ? 187.402 139.050 175.648 1.00 127.04 ? 102  ILE A O    1 
ATOM   1360 C CB   . ILE A 1 87  ? 189.033 141.660 176.708 1.00 123.92 ? 102  ILE A CB   1 
ATOM   1361 C CG1  . ILE A 1 87  ? 189.336 140.545 177.726 1.00 121.10 ? 102  ILE A CG1  1 
ATOM   1362 C CG2  . ILE A 1 87  ? 189.012 143.048 177.351 1.00 129.15 ? 102  ILE A CG2  1 
ATOM   1363 C CD1  . ILE A 1 87  ? 190.632 140.748 178.507 1.00 126.75 ? 102  ILE A CD1  1 
ATOM   1364 H H    . ILE A 1 87  ? 186.347 140.561 177.324 1.00 127.85 ? 102  ILE A H    1 
ATOM   1365 H HA   . ILE A 1 87  ? 187.599 142.216 175.224 1.00 127.90 ? 102  ILE A HA   1 
ATOM   1366 H HB   . ILE A 1 87  ? 189.838 141.662 175.972 1.00 126.75 ? 102  ILE A HB   1 
ATOM   1367 H HG12 . ILE A 1 87  ? 188.513 140.469 178.438 1.00 126.81 ? 102  ILE A HG12 1 
ATOM   1368 H HG13 . ILE A 1 87  ? 189.424 139.594 177.202 1.00 126.55 ? 102  ILE A HG13 1 
ATOM   1369 H HG21 . ILE A 1 87  ? 188.684 143.791 176.625 1.00 127.62 ? 102  ILE A HG21 1 
ATOM   1370 H HG22 . ILE A 1 87  ? 188.343 143.062 178.212 1.00 127.98 ? 102  ILE A HG22 1 
ATOM   1371 H HG23 . ILE A 1 87  ? 190.018 143.313 177.677 1.00 127.71 ? 102  ILE A HG23 1 
ATOM   1372 H HD11 . ILE A 1 87  ? 190.815 139.865 179.119 1.00 127.06 ? 102  ILE A HD11 1 
ATOM   1373 H HD12 . ILE A 1 87  ? 190.548 141.613 179.165 1.00 127.76 ? 102  ILE A HD12 1 
ATOM   1374 H HD13 . ILE A 1 87  ? 191.464 140.886 177.817 1.00 127.27 ? 102  ILE A HD13 1 
ATOM   1375 N N    . PHE A 1 88  ? 188.374 140.191 173.981 1.00 124.11 ? 103  PHE A N    1 
ATOM   1376 C CA   . PHE A 1 88  ? 188.803 139.054 173.189 1.00 112.73 ? 103  PHE A CA   1 
ATOM   1377 C C    . PHE A 1 88  ? 190.325 138.993 173.201 1.00 116.47 ? 103  PHE A C    1 
ATOM   1378 O O    . PHE A 1 88  ? 190.964 140.010 172.938 1.00 125.02 ? 103  PHE A O    1 
ATOM   1379 C CB   . PHE A 1 88  ? 188.274 139.210 171.770 1.00 114.50 ? 103  PHE A CB   1 
ATOM   1380 C CG   . PHE A 1 88  ? 188.692 138.094 170.854 1.00 110.05 ? 103  PHE A CG   1 
ATOM   1381 C CD1  . PHE A 1 88  ? 188.218 136.800 171.097 1.00 117.84 ? 103  PHE A CD1  1 
ATOM   1382 C CD2  . PHE A 1 88  ? 189.541 138.333 169.765 1.00 116.35 ? 103  PHE A CD2  1 
ATOM   1383 C CE1  . PHE A 1 88  ? 188.611 135.736 170.275 1.00 125.45 ? 103  PHE A CE1  1 
ATOM   1384 C CE2  . PHE A 1 88  ? 189.929 137.269 168.939 1.00 122.10 ? 103  PHE A CE2  1 
ATOM   1385 C CZ   . PHE A 1 88  ? 189.470 135.970 169.196 1.00 124.69 ? 103  PHE A CZ   1 
ATOM   1386 H H    . PHE A 1 88  ? 188.654 141.104 173.653 1.00 123.42 ? 103  PHE A H    1 
ATOM   1387 H HA   . PHE A 1 88  ? 188.404 138.132 173.613 1.00 120.84 ? 103  PHE A HA   1 
ATOM   1388 H HB2  . PHE A 1 88  ? 187.185 139.230 171.800 1.00 122.23 ? 103  PHE A HB2  1 
ATOM   1389 H HB3  . PHE A 1 88  ? 188.613 140.162 171.361 1.00 121.33 ? 103  PHE A HB3  1 
ATOM   1390 H HD1  . PHE A 1 88  ? 187.559 136.615 171.933 1.00 122.10 ? 103  PHE A HD1  1 
ATOM   1391 H HD2  . PHE A 1 88  ? 189.897 139.332 169.562 1.00 121.51 ? 103  PHE A HD2  1 
ATOM   1392 H HE1  . PHE A 1 88  ? 188.260 134.737 170.484 1.00 123.89 ? 103  PHE A HE1  1 
ATOM   1393 H HE2  . PHE A 1 88  ? 190.590 137.441 168.102 1.00 121.91 ? 103  PHE A HE2  1 
ATOM   1394 H HZ   . PHE A 1 88  ? 189.774 135.150 168.563 1.00 122.80 ? 103  PHE A HZ   1 
ATOM   1395 N N    . SER A 1 89  ? 190.907 137.839 173.502 1.00 124.62 ? 104  SER A N    1 
ATOM   1396 C CA   . SER A 1 89  ? 192.353 137.622 173.521 1.00 120.00 ? 104  SER A CA   1 
ATOM   1397 C C    . SER A 1 89  ? 192.785 136.697 172.397 1.00 121.16 ? 104  SER A C    1 
ATOM   1398 O O    . SER A 1 89  ? 192.209 135.627 172.246 1.00 139.01 ? 104  SER A O    1 
ATOM   1399 C CB   . SER A 1 89  ? 192.825 136.980 174.822 1.00 129.22 ? 104  SER A CB   1 
ATOM   1400 O OG   . SER A 1 89  ? 192.404 137.687 175.967 1.00 141.36 ? 104  SER A OG   1 
ATOM   1401 H H    . SER A 1 89  ? 190.310 137.050 173.702 1.00 129.18 ? 104  SER A H    1 
ATOM   1402 H HA   . SER A 1 89  ? 192.862 138.580 173.421 1.00 127.46 ? 104  SER A HA   1 
ATOM   1403 H HB2  . SER A 1 89  ? 192.447 135.959 174.878 1.00 128.98 ? 104  SER A HB2  1 
ATOM   1404 H HB3  . SER A 1 89  ? 193.914 136.941 174.815 1.00 129.08 ? 104  SER A HB3  1 
ATOM   1405 H HG   . SER A 1 89  ? 192.871 137.320 176.722 1.00 130.88 ? 104  SER A HG   1 
ATOM   1406 N N    . ARG A 1 90  ? 193.846 137.044 171.677 1.00 112.90 ? 105  ARG A N    1 
ATOM   1407 C CA   . ARG A 1 90  ? 194.592 136.154 170.779 1.00 117.43 ? 105  ARG A CA   1 
ATOM   1408 C C    . ARG A 1 90  ? 195.974 135.973 171.385 1.00 127.70 ? 105  ARG A C    1 
ATOM   1409 O O    . ARG A 1 90  ? 196.714 136.938 171.532 1.00 139.78 ? 105  ARG A O    1 
ATOM   1410 C CB   . ARG A 1 90  ? 194.598 136.786 169.377 1.00 126.71 ? 105  ARG A CB   1 
ATOM   1411 C CG   . ARG A 1 90  ? 195.704 136.310 168.431 1.00 123.45 ? 105  ARG A CG   1 
ATOM   1412 C CD   . ARG A 1 90  ? 195.552 137.020 167.082 1.00 128.24 ? 105  ARG A CD   1 
ATOM   1413 N NE   . ARG A 1 90  ? 196.826 137.102 166.352 1.00 134.25 ? 105  ARG A NE   1 
ATOM   1414 C CZ   . ARG A 1 90  ? 197.389 136.174 165.604 1.00 137.78 ? 105  ARG A CZ   1 
ATOM   1415 N NH1  . ARG A 1 90  ? 198.495 136.439 164.979 1.00 138.93 ? 105  ARG A NH1  1 
ATOM   1416 N NH2  . ARG A 1 90  ? 196.872 134.992 165.438 1.00 130.42 ? 105  ARG A NH2  1 
ATOM   1417 H H    . ARG A 1 90  ? 194.258 137.944 171.878 1.00 128.41 ? 105  ARG A H    1 
ATOM   1418 H HA   . ARG A 1 90  ? 194.117 135.175 170.720 1.00 127.94 ? 105  ARG A HA   1 
ATOM   1419 H HB2  . ARG A 1 90  ? 193.628 136.597 168.916 1.00 129.42 ? 105  ARG A HB2  1 
ATOM   1420 H HB3  . ARG A 1 90  ? 194.694 137.866 169.483 1.00 130.14 ? 105  ARG A HB3  1 
ATOM   1421 H HG2  . ARG A 1 90  ? 196.674 136.566 168.856 1.00 128.89 ? 105  ARG A HG2  1 
ATOM   1422 H HG3  . ARG A 1 90  ? 195.648 135.229 168.295 1.00 128.14 ? 105  ARG A HG3  1 
ATOM   1423 H HD2  . ARG A 1 90  ? 194.794 136.519 166.481 1.00 129.15 ? 105  ARG A HD2  1 
ATOM   1424 H HD3  . ARG A 1 90  ? 195.208 138.039 167.257 1.00 129.11 ? 105  ARG A HD3  1 
ATOM   1425 H HE   . ARG A 1 90  ? 197.324 137.980 166.406 1.00 129.13 ? 105  ARG A HE   1 
ATOM   1426 H HH11 . ARG A 1 90  ? 198.928 137.347 165.070 1.00 130.27 ? 105  ARG A HH11 1 
ATOM   1427 H HH12 . ARG A 1 90  ? 198.948 135.722 164.430 1.00 129.93 ? 105  ARG A HH12 1 
ATOM   1428 H HH21 . ARG A 1 90  ? 195.999 134.757 165.887 1.00 128.82 ? 105  ARG A HH21 1 
ATOM   1429 H HH22 . ARG A 1 90  ? 197.353 134.309 164.870 1.00 129.40 ? 105  ARG A HH22 1 
ATOM   1430 N N    . VAL A 1 91  ? 196.320 134.756 171.774 1.00 129.84 ? 106  VAL A N    1 
ATOM   1431 C CA   . VAL A 1 91  ? 197.474 134.479 172.634 1.00 124.51 ? 106  VAL A CA   1 
ATOM   1432 C C    . VAL A 1 91  ? 198.452 133.566 171.930 1.00 125.46 ? 106  VAL A C    1 
ATOM   1433 O O    . VAL A 1 91  ? 198.079 132.453 171.575 1.00 132.55 ? 106  VAL A O    1 
ATOM   1434 C CB   . VAL A 1 91  ? 197.009 133.827 173.939 1.00 122.72 ? 106  VAL A CB   1 
ATOM   1435 C CG1  . VAL A 1 91  ? 198.184 133.663 174.895 1.00 129.55 ? 106  VAL A CG1  1 
ATOM   1436 C CG2  . VAL A 1 91  ? 195.932 134.663 174.626 1.00 132.23 ? 106  VAL A CG2  1 
ATOM   1437 H H    . VAL A 1 91  ? 195.658 134.006 171.641 1.00 130.77 ? 106  VAL A H    1 
ATOM   1438 H HA   . VAL A 1 91  ? 197.989 135.405 172.887 1.00 129.94 ? 106  VAL A HA   1 
ATOM   1439 H HB   . VAL A 1 91  ? 196.589 132.842 173.735 1.00 129.35 ? 106  VAL A HB   1 
ATOM   1440 H HG11 . VAL A 1 91  ? 197.826 133.298 175.857 1.00 130.71 ? 106  VAL A HG11 1 
ATOM   1441 H HG12 . VAL A 1 91  ? 198.692 134.617 175.033 1.00 130.74 ? 106  VAL A HG12 1 
ATOM   1442 H HG13 . VAL A 1 91  ? 198.891 132.931 174.502 1.00 129.96 ? 106  VAL A HG13 1 
ATOM   1443 H HG21 . VAL A 1 91  ? 195.020 134.663 174.029 1.00 130.66 ? 106  VAL A HG21 1 
ATOM   1444 H HG22 . VAL A 1 91  ? 196.282 135.686 174.758 1.00 130.74 ? 106  VAL A HG22 1 
ATOM   1445 H HG23 . VAL A 1 91  ? 195.695 134.230 175.598 1.00 130.50 ? 106  VAL A HG23 1 
ATOM   1446 N N    . LYS A 1 92  ? 199.704 133.982 171.746 1.00 139.09 ? 107  LYS A N    1 
ATOM   1447 C CA   . LYS A 1 92  ? 200.734 133.087 171.212 1.00 144.26 ? 107  LYS A CA   1 
ATOM   1448 C C    . LYS A 1 92  ? 201.113 132.081 172.283 1.00 142.20 ? 107  LYS A C    1 
ATOM   1449 O O    . LYS A 1 92  ? 201.457 132.476 173.389 1.00 146.35 ? 107  LYS A O    1 
ATOM   1450 C CB   . LYS A 1 92  ? 201.952 133.894 170.745 1.00 146.90 ? 107  LYS A CB   1 
ATOM   1451 C CG   . LYS A 1 92  ? 203.102 132.991 170.281 1.00 146.14 ? 107  LYS A CG   1 
ATOM   1452 C CD   . LYS A 1 92  ? 204.286 133.804 169.750 1.00 146.12 ? 107  LYS A CD   1 
ATOM   1453 C CE   . LYS A 1 92  ? 205.494 132.869 169.648 1.00 145.22 ? 107  LYS A CE   1 
ATOM   1454 N NZ   . LYS A 1 92  ? 206.723 133.573 169.209 1.00 151.27 ? 107  LYS A NZ   1 
ATOM   1455 H H    . LYS A 1 92  ? 199.985 134.871 172.132 1.00 144.51 ? 107  LYS A H    1 
ATOM   1456 H HA   . LYS A 1 92  ? 200.334 132.543 170.356 1.00 145.36 ? 107  LYS A HA   1 
ATOM   1457 H HB2  . LYS A 1 92  ? 201.654 134.537 169.917 1.00 144.90 ? 107  LYS A HB2  1 
ATOM   1458 H HB3  . LYS A 1 92  ? 202.305 134.515 171.568 1.00 145.44 ? 107  LYS A HB3  1 
ATOM   1459 H HG2  . LYS A 1 92  ? 203.446 132.396 171.127 1.00 145.08 ? 107  LYS A HG2  1 
ATOM   1460 H HG3  . LYS A 1 92  ? 202.748 132.320 169.499 1.00 144.86 ? 107  LYS A HG3  1 
ATOM   1461 H HD2  . LYS A 1 92  ? 204.040 134.220 168.773 1.00 144.64 ? 107  LYS A HD2  1 
ATOM   1462 H HD3  . LYS A 1 92  ? 204.513 134.612 170.445 1.00 145.83 ? 107  LYS A HD3  1 
ATOM   1463 H HE2  . LYS A 1 92  ? 205.664 132.432 170.632 1.00 144.94 ? 107  LYS A HE2  1 
ATOM   1464 H HE3  . LYS A 1 92  ? 205.258 132.057 168.961 1.00 144.49 ? 107  LYS A HE3  1 
ATOM   1465 H HZ1  . LYS A 1 92  ? 207.523 132.982 169.388 1.00 146.10 ? 107  LYS A HZ1  1 
ATOM   1466 H HZ2  . LYS A 1 92  ? 206.868 134.432 169.719 1.00 145.91 ? 107  LYS A HZ2  1 
ATOM   1467 H HZ3  . LYS A 1 92  ? 206.692 133.782 168.221 1.00 145.69 ? 107  LYS A HZ3  1 
ATOM   1468 N N    . ASN A 1 93  ? 201.118 130.797 171.965 1.00 143.72 ? 108  ASN A N    1 
ATOM   1469 C CA   . ASN A 1 93  ? 201.689 129.780 172.838 1.00 142.77 ? 108  ASN A CA   1 
ATOM   1470 C C    . ASN A 1 93  ? 203.206 129.704 172.617 1.00 142.97 ? 108  ASN A C    1 
ATOM   1471 O O    . ASN A 1 93  ? 203.663 129.150 171.620 1.00 146.05 ? 108  ASN A O    1 
ATOM   1472 C CB   . ASN A 1 93  ? 200.984 128.466 172.521 1.00 141.47 ? 108  ASN A CB   1 
ATOM   1473 C CG   . ASN A 1 93  ? 201.592 127.286 173.235 1.00 144.93 ? 108  ASN A CG   1 
ATOM   1474 O OD1  . ASN A 1 93  ? 202.273 127.405 174.239 1.00 149.25 ? 108  ASN A OD1  1 
ATOM   1475 N ND2  . ASN A 1 93  ? 201.357 126.105 172.732 1.00 151.76 ? 108  ASN A ND2  1 
ATOM   1476 H H    . ASN A 1 93  ? 200.836 130.531 171.032 1.00 146.06 ? 108  ASN A H    1 
ATOM   1477 H HA   . ASN A 1 93  ? 201.506 130.028 173.884 1.00 146.10 ? 108  ASN A HA   1 
ATOM   1478 H HB2  . ASN A 1 93  ? 199.933 128.535 172.802 1.00 145.60 ? 108  ASN A HB2  1 
ATOM   1479 H HB3  . ASN A 1 93  ? 201.046 128.288 171.447 1.00 145.91 ? 108  ASN A HB3  1 
ATOM   1480 H HD21 . ASN A 1 93  ? 200.850 126.055 171.860 1.00 146.99 ? 108  ASN A HD21 1 
ATOM   1481 H HD22 . ASN A 1 93  ? 201.830 125.288 173.091 1.00 146.87 ? 108  ASN A HD22 1 
ATOM   1482 N N    . THR A 1 94  ? 204.007 130.274 173.509 1.00 148.64 ? 109  THR A N    1 
ATOM   1483 C CA   . THR A 1 94  ? 205.465 130.296 173.369 1.00 148.49 ? 109  THR A CA   1 
ATOM   1484 C C    . THR A 1 94  ? 206.041 128.923 173.699 1.00 150.48 ? 109  THR A C    1 
ATOM   1485 O O    . THR A 1 94  ? 206.233 128.578 174.861 1.00 155.43 ? 109  THR A O    1 
ATOM   1486 C CB   . THR A 1 94  ? 206.070 131.384 174.258 1.00 153.05 ? 109  THR A CB   1 
ATOM   1487 O OG1  . THR A 1 94  ? 205.485 132.624 173.934 1.00 153.01 ? 109  THR A OG1  1 
ATOM   1488 C CG2  . THR A 1 94  ? 207.575 131.530 174.067 1.00 154.13 ? 109  THR A CG2  1 
ATOM   1489 H H    . THR A 1 94  ? 203.615 130.686 174.344 1.00 152.41 ? 109  THR A H    1 
ATOM   1490 H HA   . THR A 1 94  ? 205.722 130.536 172.336 1.00 151.46 ? 109  THR A HA   1 
ATOM   1491 H HB   . THR A 1 94  ? 205.868 131.163 175.306 1.00 152.84 ? 109  THR A HB   1 
ATOM   1492 H HG1  . THR A 1 94  ? 206.046 133.086 173.306 1.00 152.85 ? 109  THR A HG1  1 
ATOM   1493 H HG21 . THR A 1 94  ? 207.943 132.360 174.670 1.00 152.98 ? 109  THR A HG21 1 
ATOM   1494 H HG22 . THR A 1 94  ? 208.077 130.620 174.391 1.00 152.21 ? 109  THR A HG22 1 
ATOM   1495 H HG23 . THR A 1 94  ? 207.806 131.714 173.017 1.00 152.91 ? 109  THR A HG23 1 
ATOM   1496 N N    . LYS A 1 95  ? 206.291 128.115 172.668 1.00 147.22 ? 110  LYS A N    1 
ATOM   1497 C CA   . LYS A 1 95  ? 206.797 126.742 172.781 1.00 147.79 ? 110  LYS A CA   1 
ATOM   1498 C C    . LYS A 1 95  ? 208.316 126.730 172.951 1.00 148.96 ? 110  LYS A C    1 
ATOM   1499 O O    . LYS A 1 95  ? 209.052 126.880 171.979 1.00 151.67 ? 110  LYS A O    1 
ATOM   1500 C CB   . LYS A 1 95  ? 206.341 125.966 171.537 1.00 146.83 ? 110  LYS A CB   1 
ATOM   1501 C CG   . LYS A 1 95  ? 204.840 125.634 171.611 1.00 147.27 ? 110  LYS A CG   1 
ATOM   1502 C CD   . LYS A 1 95  ? 204.122 125.630 170.254 1.00 148.82 ? 110  LYS A CD   1 
ATOM   1503 C CE   . LYS A 1 95  ? 204.811 124.753 169.207 1.00 149.41 ? 110  LYS A CE   1 
ATOM   1504 N NZ   . LYS A 1 95  ? 204.011 124.670 167.959 1.00 155.58 ? 110  LYS A NZ   1 
ATOM   1505 H H    . LYS A 1 95  ? 206.048 128.449 171.747 1.00 150.05 ? 110  LYS A H    1 
ATOM   1506 H HA   . LYS A 1 95  ? 206.367 126.261 173.661 1.00 150.08 ? 110  LYS A HA   1 
ATOM   1507 H HB2  . LYS A 1 95  ? 206.553 126.561 170.649 1.00 150.21 ? 110  LYS A HB2  1 
ATOM   1508 H HB3  . LYS A 1 95  ? 206.897 125.031 171.462 1.00 149.60 ? 110  LYS A HB3  1 
ATOM   1509 H HG2  . LYS A 1 95  ? 204.722 124.660 172.086 1.00 149.84 ? 110  LYS A HG2  1 
ATOM   1510 H HG3  . LYS A 1 95  ? 204.333 126.365 172.242 1.00 150.12 ? 110  LYS A HG3  1 
ATOM   1511 H HD2  . LYS A 1 95  ? 203.103 125.275 170.412 1.00 150.31 ? 110  LYS A HD2  1 
ATOM   1512 H HD3  . LYS A 1 95  ? 204.073 126.653 169.883 1.00 150.33 ? 110  LYS A HD3  1 
ATOM   1513 H HE2  . LYS A 1 95  ? 205.791 125.177 168.990 1.00 150.41 ? 110  LYS A HE2  1 
ATOM   1514 H HE3  . LYS A 1 95  ? 204.964 123.756 169.623 1.00 149.72 ? 110  LYS A HE3  1 
ATOM   1515 H HZ1  . LYS A 1 95  ? 203.765 125.580 167.596 1.00 151.02 ? 110  LYS A HZ1  1 
ATOM   1516 H HZ2  . LYS A 1 95  ? 203.138 124.186 168.115 1.00 150.82 ? 110  LYS A HZ2  1 
ATOM   1517 H HZ3  . LYS A 1 95  ? 204.513 124.181 167.232 1.00 151.41 ? 110  LYS A HZ3  1 
ATOM   1518 N N    . LEU A 1 96  ? 208.787 126.565 174.181 1.00 156.59 ? 111  LEU A N    1 
ATOM   1519 C CA   . LEU A 1 96  ? 210.205 126.407 174.516 1.00 153.27 ? 111  LEU A CA   1 
ATOM   1520 C C    . LEU A 1 96  ? 210.634 124.942 174.458 1.00 157.95 ? 111  LEU A C    1 
ATOM   1521 O O    . LEU A 1 96  ? 209.798 124.041 174.480 1.00 162.64 ? 111  LEU A O    1 
ATOM   1522 C CB   . LEU A 1 96  ? 210.479 126.996 175.909 1.00 153.08 ? 111  LEU A CB   1 
ATOM   1523 C CG   . LEU A 1 96  ? 210.061 128.466 176.053 1.00 156.36 ? 111  LEU A CG   1 
ATOM   1524 C CD1  . LEU A 1 96  ? 210.499 128.979 177.418 1.00 158.16 ? 111  LEU A CD1  1 
ATOM   1525 C CD2  . LEU A 1 96  ? 210.690 129.349 174.979 1.00 160.07 ? 111  LEU A CD2  1 
ATOM   1526 H H    . LEU A 1 96  ? 208.111 126.389 174.912 1.00 158.41 ? 111  LEU A H    1 
ATOM   1527 H HA   . LEU A 1 96  ? 210.813 126.938 173.783 1.00 157.71 ? 111  LEU A HA   1 
ATOM   1528 H HB2  . LEU A 1 96  ? 209.943 126.410 176.654 1.00 157.99 ? 111  LEU A HB2  1 
ATOM   1529 H HB3  . LEU A 1 96  ? 211.546 126.918 176.119 1.00 157.41 ? 111  LEU A HB3  1 
ATOM   1530 H HG   . LEU A 1 96  ? 208.976 128.546 175.988 1.00 158.43 ? 111  LEU A HG   1 
ATOM   1531 H HD11 . LEU A 1 96  ? 210.129 129.995 177.561 1.00 159.12 ? 111  LEU A HD11 1 
ATOM   1532 H HD12 . LEU A 1 96  ? 210.087 128.343 178.201 1.00 158.37 ? 111  LEU A HD12 1 
ATOM   1533 H HD13 . LEU A 1 96  ? 211.587 128.983 177.486 1.00 158.19 ? 111  LEU A HD13 1 
ATOM   1534 H HD21 . LEU A 1 96  ? 210.358 130.377 175.123 1.00 158.50 ? 111  LEU A HD21 1 
ATOM   1535 H HD22 . LEU A 1 96  ? 210.357 129.041 173.989 1.00 158.79 ? 111  LEU A HD22 1 
ATOM   1536 H HD23 . LEU A 1 96  ? 211.777 129.305 175.036 1.00 158.87 ? 111  LEU A HD23 1 
ATOM   1537 N N    . TYR A 1 97  ? 211.944 124.699 174.459 1.00 158.81 ? 112  TYR A N    1 
ATOM   1538 C CA   . TYR A 1 97  ? 212.511 123.355 174.554 1.00 162.09 ? 112  TYR A CA   1 
ATOM   1539 C C    . TYR A 1 97  ? 213.628 123.275 175.594 1.00 163.35 ? 112  TYR A C    1 
ATOM   1540 O O    . TYR A 1 97  ? 214.482 124.159 175.673 1.00 164.54 ? 112  TYR A O    1 
ATOM   1541 C CB   . TYR A 1 97  ? 213.020 122.893 173.187 1.00 158.63 ? 112  TYR A CB   1 
ATOM   1542 C CG   . TYR A 1 97  ? 211.933 122.726 172.151 1.00 160.52 ? 112  TYR A CG   1 
ATOM   1543 C CD1  . TYR A 1 97  ? 211.250 121.501 172.050 1.00 161.37 ? 112  TYR A CD1  1 
ATOM   1544 C CD2  . TYR A 1 97  ? 211.610 123.786 171.287 1.00 156.71 ? 112  TYR A CD2  1 
ATOM   1545 C CE1  . TYR A 1 97  ? 210.251 121.329 171.076 1.00 160.62 ? 112  TYR A CE1  1 
ATOM   1546 C CE2  . TYR A 1 97  ? 210.605 123.620 170.319 1.00 158.43 ? 112  TYR A CE2  1 
ATOM   1547 C CZ   . TYR A 1 97  ? 209.927 122.391 170.208 1.00 161.84 ? 112  TYR A CZ   1 
ATOM   1548 O OH   . TYR A 1 97  ? 208.975 122.228 169.255 1.00 164.67 ? 112  TYR A OH   1 
ATOM   1549 H H    . TYR A 1 97  ? 212.583 125.480 174.447 1.00 159.96 ? 112  TYR A H    1 
ATOM   1550 H HA   . TYR A 1 97  ? 211.729 122.661 174.862 1.00 161.11 ? 112  TYR A HA   1 
ATOM   1551 H HB2  . TYR A 1 97  ? 213.760 123.606 172.821 1.00 160.42 ? 112  TYR A HB2  1 
ATOM   1552 H HB3  . TYR A 1 97  ? 213.527 121.935 173.308 1.00 160.08 ? 112  TYR A HB3  1 
ATOM   1553 H HD1  . TYR A 1 97  ? 211.497 120.689 172.717 1.00 160.82 ? 112  TYR A HD1  1 
ATOM   1554 H HD2  . TYR A 1 97  ? 212.132 124.728 171.365 1.00 160.06 ? 112  TYR A HD2  1 
ATOM   1555 H HE1  . TYR A 1 97  ? 209.735 120.383 170.990 1.00 160.75 ? 112  TYR A HE1  1 
ATOM   1556 H HE2  . TYR A 1 97  ? 210.350 124.431 169.651 1.00 160.65 ? 112  TYR A HE2  1 
ATOM   1557 H HH   . TYR A 1 97  ? 208.679 121.318 169.203 1.00 161.42 ? 112  TYR A HH   1 
ATOM   1558 N N    . VAL A 1 98  ? 213.659 122.182 176.356 1.00 174.17 ? 113  VAL A N    1 
ATOM   1559 C CA   . VAL A 1 98  ? 214.792 121.792 177.213 1.00 175.99 ? 113  VAL A CA   1 
ATOM   1560 C C    . VAL A 1 98  ? 215.106 120.322 176.942 1.00 178.58 ? 113  VAL A C    1 
ATOM   1561 O O    . VAL A 1 98  ? 214.202 119.493 176.997 1.00 178.65 ? 113  VAL A O    1 
ATOM   1562 C CB   . VAL A 1 98  ? 214.480 122.030 178.700 1.00 174.10 ? 113  VAL A CB   1 
ATOM   1563 C CG1  . VAL A 1 98  ? 215.642 121.601 179.599 1.00 172.86 ? 113  VAL A CG1  1 
ATOM   1564 C CG2  . VAL A 1 98  ? 214.193 123.505 178.996 1.00 174.37 ? 113  VAL A CG2  1 
ATOM   1565 H H    . VAL A 1 98  ? 212.900 121.523 176.262 1.00 174.16 ? 113  VAL A H    1 
ATOM   1566 H HA   . VAL A 1 98  ? 215.672 122.381 176.953 1.00 174.73 ? 113  VAL A HA   1 
ATOM   1567 H HB   . VAL A 1 98  ? 213.602 121.448 178.982 1.00 174.42 ? 113  VAL A HB   1 
ATOM   1568 H HG11 . VAL A 1 98  ? 215.406 121.825 180.639 1.00 174.52 ? 113  VAL A HG11 1 
ATOM   1569 H HG12 . VAL A 1 98  ? 216.552 122.133 179.318 1.00 174.36 ? 113  VAL A HG12 1 
ATOM   1570 H HG13 . VAL A 1 98  ? 215.810 120.527 179.518 1.00 174.61 ? 113  VAL A HG13 1 
ATOM   1571 H HG21 . VAL A 1 98  ? 213.324 123.842 178.432 1.00 174.80 ? 113  VAL A HG21 1 
ATOM   1572 H HG22 . VAL A 1 98  ? 215.064 124.107 178.733 1.00 174.62 ? 113  VAL A HG22 1 
ATOM   1573 H HG23 . VAL A 1 98  ? 213.977 123.634 180.057 1.00 174.44 ? 113  VAL A HG23 1 
ATOM   1574 N N    . ASN A 1 99  ? 216.357 119.984 176.615 1.00 192.70 ? 114  ASN A N    1 
ATOM   1575 C CA   . ASN A 1 99  ? 216.779 118.626 176.225 1.00 193.64 ? 114  ASN A CA   1 
ATOM   1576 C C    . ASN A 1 99  ? 215.817 117.957 175.212 1.00 192.71 ? 114  ASN A C    1 
ATOM   1577 O O    . ASN A 1 99  ? 215.412 116.805 175.378 1.00 190.76 ? 114  ASN A O    1 
ATOM   1578 C CB   . ASN A 1 99  ? 217.060 117.767 177.478 1.00 193.26 ? 114  ASN A CB   1 
ATOM   1579 C CG   . ASN A 1 99  ? 218.220 118.255 178.328 1.00 193.10 ? 114  ASN A CG   1 
ATOM   1580 O OD1  . ASN A 1 99  ? 218.991 119.127 177.953 1.00 192.17 ? 114  ASN A OD1  1 
ATOM   1581 N ND2  . ASN A 1 99  ? 218.395 117.690 179.499 1.00 189.03 ? 114  ASN A ND2  1 
ATOM   1582 H H    . ASN A 1 99  ? 217.065 120.705 176.622 1.00 189.78 ? 114  ASN A H    1 
ATOM   1583 H HA   . ASN A 1 99  ? 217.723 118.724 175.688 1.00 190.28 ? 114  ASN A HA   1 
ATOM   1584 H HB2  . ASN A 1 99  ? 216.163 117.725 178.095 1.00 190.18 ? 114  ASN A HB2  1 
ATOM   1585 H HB3  . ASN A 1 99  ? 217.301 116.750 177.168 1.00 190.37 ? 114  ASN A HB3  1 
ATOM   1586 H HD21 . ASN A 1 99  ? 217.770 116.960 179.809 1.00 189.64 ? 114  ASN A HD21 1 
ATOM   1587 H HD22 . ASN A 1 99  ? 219.169 117.996 180.071 1.00 189.77 ? 114  ASN A HD22 1 
ATOM   1588 N N    . LYS A 1 100 ? 215.394 118.709 174.186 1.00 186.27 ? 115  LYS A N    1 
ATOM   1589 C CA   . LYS A 1 100 ? 214.405 118.304 173.161 1.00 184.90 ? 115  LYS A CA   1 
ATOM   1590 C C    . LYS A 1 100 ? 213.018 117.886 173.695 1.00 185.68 ? 115  LYS A C    1 
ATOM   1591 O O    . LYS A 1 100 ? 212.239 117.274 172.965 1.00 184.63 ? 115  LYS A O    1 
ATOM   1592 C CB   . LYS A 1 100 ? 215.007 117.265 172.192 1.00 184.95 ? 115  LYS A CB   1 
ATOM   1593 C CG   . LYS A 1 100 ? 216.243 117.787 171.444 1.00 184.95 ? 115  LYS A CG   1 
ATOM   1594 C CD   . LYS A 1 100 ? 216.748 116.745 170.442 1.00 185.38 ? 115  LYS A CD   1 
ATOM   1595 C CE   . LYS A 1 100 ? 217.969 117.292 169.700 1.00 187.42 ? 115  LYS A CE   1 
ATOM   1596 N NZ   . LYS A 1 100 ? 218.492 116.312 168.719 1.00 187.80 ? 115  LYS A NZ   1 
ATOM   1597 H H    . LYS A 1 100 ? 215.791 119.635 174.113 1.00 184.50 ? 115  LYS A H    1 
ATOM   1598 H HA   . LYS A 1 100 ? 214.195 119.191 172.562 1.00 184.24 ? 115  LYS A HA   1 
ATOM   1599 H HB2  . LYS A 1 100 ? 215.271 116.360 172.738 1.00 184.99 ? 115  LYS A HB2  1 
ATOM   1600 H HB3  . LYS A 1 100 ? 214.259 117.001 171.445 1.00 184.94 ? 115  LYS A HB3  1 
ATOM   1601 H HG2  . LYS A 1 100 ? 215.979 118.700 170.911 1.00 184.96 ? 115  LYS A HG2  1 
ATOM   1602 H HG3  . LYS A 1 100 ? 217.037 118.009 172.157 1.00 184.93 ? 115  LYS A HG3  1 
ATOM   1603 H HD2  . LYS A 1 100 ? 217.020 115.835 170.975 1.00 184.80 ? 115  LYS A HD2  1 
ATOM   1604 H HD3  . LYS A 1 100 ? 215.957 116.518 169.727 1.00 185.04 ? 115  LYS A HD3  1 
ATOM   1605 H HE2  . LYS A 1 100 ? 217.684 118.214 169.190 1.00 185.41 ? 115  LYS A HE2  1 
ATOM   1606 H HE3  . LYS A 1 100 ? 218.741 117.538 170.430 1.00 185.30 ? 115  LYS A HE3  1 
ATOM   1607 H HZ1  . LYS A 1 100 ? 219.297 116.681 168.232 1.00 185.27 ? 115  LYS A HZ1  1 
ATOM   1608 H HZ2  . LYS A 1 100 ? 218.775 115.457 169.175 1.00 185.21 ? 115  LYS A HZ2  1 
ATOM   1609 H HZ3  . LYS A 1 100 ? 217.793 116.081 168.028 1.00 185.28 ? 115  LYS A HZ3  1 
ATOM   1610 N N    . THR A 1 101 ? 212.661 118.260 174.924 1.00 176.57 ? 116  THR A N    1 
ATOM   1611 C CA   . THR A 1 101 ? 211.292 118.159 175.464 1.00 174.23 ? 116  THR A CA   1 
ATOM   1612 C C    . THR A 1 101 ? 210.606 119.520 175.395 1.00 174.03 ? 116  THR A C    1 
ATOM   1613 O O    . THR A 1 101 ? 211.189 120.524 175.801 1.00 174.15 ? 116  THR A O    1 
ATOM   1614 C CB   . THR A 1 101 ? 211.305 117.664 176.914 1.00 172.58 ? 116  THR A CB   1 
ATOM   1615 O OG1  . THR A 1 101 ? 211.827 116.357 176.953 1.00 173.09 ? 116  THR A OG1  1 
ATOM   1616 C CG2  . THR A 1 101 ? 209.912 117.588 177.533 1.00 171.00 ? 116  THR A CG2  1 
ATOM   1617 H H    . THR A 1 101 ? 213.346 118.740 175.490 1.00 173.90 ? 116  THR A H    1 
ATOM   1618 H HA   . THR A 1 101 ? 210.709 117.449 174.878 1.00 173.14 ? 116  THR A HA   1 
ATOM   1619 H HB   . THR A 1 101 ? 211.926 118.319 177.527 1.00 173.14 ? 116  THR A HB   1 
ATOM   1620 H HG1  . THR A 1 101 ? 212.734 116.411 176.641 1.00 173.15 ? 116  THR A HG1  1 
ATOM   1621 H HG21 . THR A 1 101 ? 209.973 117.114 178.512 1.00 172.96 ? 116  THR A HG21 1 
ATOM   1622 H HG22 . THR A 1 101 ? 209.503 118.590 177.667 1.00 172.76 ? 116  THR A HG22 1 
ATOM   1623 H HG23 . THR A 1 101 ? 209.248 117.006 176.893 1.00 172.55 ? 116  THR A HG23 1 
ATOM   1624 N N    . LEU A 1 102 ? 209.386 119.563 174.860 1.00 158.05 ? 117  LEU A N    1 
ATOM   1625 C CA   . LEU A 1 102 ? 208.599 120.785 174.687 1.00 157.20 ? 117  LEU A CA   1 
ATOM   1626 C C    . LEU A 1 102 ? 208.012 121.284 176.012 1.00 160.99 ? 117  LEU A C    1 
ATOM   1627 O O    . LEU A 1 102 ? 207.489 120.492 176.793 1.00 159.66 ? 117  LEU A O    1 
ATOM   1628 C CB   . LEU A 1 102 ? 207.513 120.495 173.635 1.00 156.55 ? 117  LEU A CB   1 
ATOM   1629 C CG   . LEU A 1 102 ? 206.605 121.692 173.296 1.00 160.33 ? 117  LEU A CG   1 
ATOM   1630 C CD1  . LEU A 1 102 ? 206.215 121.656 171.822 1.00 159.92 ? 117  LEU A CD1  1 
ATOM   1631 C CD2  . LEU A 1 102 ? 205.305 121.671 174.098 1.00 159.73 ? 117  LEU A CD2  1 
ATOM   1632 H H    . LEU A 1 102 ? 208.963 118.695 174.565 1.00 159.13 ? 117  LEU A H    1 
ATOM   1633 H HA   . LEU A 1 102 ? 209.253 121.563 174.291 1.00 158.89 ? 117  LEU A HA   1 
ATOM   1634 H HB2  . LEU A 1 102 ? 208.025 120.179 172.726 1.00 158.73 ? 117  LEU A HB2  1 
ATOM   1635 H HB3  . LEU A 1 102 ? 206.896 119.659 173.966 1.00 158.96 ? 117  LEU A HB3  1 
ATOM   1636 H HG   . LEU A 1 102 ? 207.136 122.624 173.485 1.00 159.16 ? 117  LEU A HG   1 
ATOM   1637 H HD11 . LEU A 1 102 ? 207.109 121.755 171.207 1.00 159.01 ? 117  LEU A HD11 1 
ATOM   1638 H HD12 . LEU A 1 102 ? 205.542 122.482 171.596 1.00 158.77 ? 117  LEU A HD12 1 
ATOM   1639 H HD13 . LEU A 1 102 ? 205.718 120.714 171.590 1.00 158.91 ? 117  LEU A HD13 1 
ATOM   1640 H HD21 . LEU A 1 102 ? 205.509 121.704 175.168 1.00 158.70 ? 117  LEU A HD21 1 
ATOM   1641 H HD22 . LEU A 1 102 ? 204.745 120.764 173.873 1.00 159.01 ? 117  LEU A HD22 1 
ATOM   1642 H HD23 . LEU A 1 102 ? 204.699 122.538 173.833 1.00 159.44 ? 117  LEU A HD23 1 
ATOM   1643 N N    . TYR A 1 103 ? 208.017 122.600 176.221 1.00 161.84 ? 118  TYR A N    1 
ATOM   1644 C CA   . TYR A 1 103 ? 207.305 123.281 177.303 1.00 156.73 ? 118  TYR A CA   1 
ATOM   1645 C C    . TYR A 1 103 ? 206.506 124.456 176.748 1.00 157.58 ? 118  TYR A C    1 
ATOM   1646 O O    . TYR A 1 103 ? 206.999 125.210 175.915 1.00 161.50 ? 118  TYR A O    1 
ATOM   1647 C CB   . TYR A 1 103 ? 208.278 123.783 178.372 1.00 154.40 ? 118  TYR A CB   1 
ATOM   1648 C CG   . TYR A 1 103 ? 208.982 122.698 179.153 1.00 161.01 ? 118  TYR A CG   1 
ATOM   1649 C CD1  . TYR A 1 103 ? 210.105 122.050 178.610 1.00 164.97 ? 118  TYR A CD1  1 
ATOM   1650 C CD2  . TYR A 1 103 ? 208.510 122.336 180.426 1.00 160.24 ? 118  TYR A CD2  1 
ATOM   1651 C CE1  . TYR A 1 103 ? 210.744 121.023 179.328 1.00 167.89 ? 118  TYR A CE1  1 
ATOM   1652 C CE2  . TYR A 1 103 ? 209.160 121.328 181.159 1.00 163.20 ? 118  TYR A CE2  1 
ATOM   1653 C CZ   . TYR A 1 103 ? 210.275 120.665 180.608 1.00 168.88 ? 118  TYR A CZ   1 
ATOM   1654 O OH   . TYR A 1 103 ? 210.890 119.682 181.315 1.00 168.79 ? 118  TYR A OH   1 
ATOM   1655 H H    . TYR A 1 103 ? 208.485 123.184 175.543 1.00 162.15 ? 118  TYR A H    1 
ATOM   1656 H HA   . TYR A 1 103 ? 206.609 122.588 177.776 1.00 161.75 ? 118  TYR A HA   1 
ATOM   1657 H HB2  . TYR A 1 103 ? 209.029 124.418 177.901 1.00 161.19 ? 118  TYR A HB2  1 
ATOM   1658 H HB3  . TYR A 1 103 ? 207.725 124.409 179.072 1.00 161.14 ? 118  TYR A HB3  1 
ATOM   1659 H HD1  . TYR A 1 103 ? 210.465 122.323 177.630 1.00 162.61 ? 118  TYR A HD1  1 
ATOM   1660 H HD2  . TYR A 1 103 ? 207.645 122.829 180.846 1.00 161.76 ? 118  TYR A HD2  1 
ATOM   1661 H HE1  . TYR A 1 103 ? 211.583 120.501 178.891 1.00 163.14 ? 118  TYR A HE1  1 
ATOM   1662 H HE2  . TYR A 1 103 ? 208.804 121.045 182.139 1.00 162.18 ? 118  TYR A HE2  1 
ATOM   1663 H HH   . TYR A 1 103 ? 211.644 119.322 180.841 1.00 163.25 ? 118  TYR A HH   1 
ATOM   1664 N N    . SER A 1 104 ? 205.284 124.642 177.230 1.00 154.00 ? 119  SER A N    1 
ATOM   1665 C CA   . SER A 1 104 ? 204.386 125.716 176.811 1.00 155.41 ? 119  SER A CA   1 
ATOM   1666 C C    . SER A 1 104 ? 204.331 126.815 177.870 1.00 156.69 ? 119  SER A C    1 
ATOM   1667 O O    . SER A 1 104 ? 203.998 126.550 179.023 1.00 160.82 ? 119  SER A O    1 
ATOM   1668 C CB   . SER A 1 104 ? 203.004 125.107 176.564 1.00 155.86 ? 119  SER A CB   1 
ATOM   1669 O OG   . SER A 1 104 ? 201.994 126.085 176.469 1.00 161.34 ? 119  SER A OG   1 
ATOM   1670 H H    . SER A 1 104 ? 204.942 123.982 177.915 1.00 157.26 ? 119  SER A H    1 
ATOM   1671 H HA   . SER A 1 104 ? 204.731 126.154 175.874 1.00 156.65 ? 119  SER A HA   1 
ATOM   1672 H HB2  . SER A 1 104 ? 203.030 124.517 175.647 1.00 156.22 ? 119  SER A HB2  1 
ATOM   1673 H HB3  . SER A 1 104 ? 202.756 124.443 177.393 1.00 156.93 ? 119  SER A HB3  1 
ATOM   1674 H HG   . SER A 1 104 ? 202.146 126.598 175.672 1.00 157.44 ? 119  SER A HG   1 
ATOM   1675 N N    . GLU A 1 105 ? 204.629 128.053 177.481 1.00 156.49 ? 120  GLU A N    1 
ATOM   1676 C CA   . GLU A 1 105 ? 204.519 129.248 178.321 1.00 153.20 ? 120  GLU A CA   1 
ATOM   1677 C C    . GLU A 1 105 ? 203.637 130.297 177.632 1.00 154.67 ? 120  GLU A C    1 
ATOM   1678 O O    . GLU A 1 105 ? 203.703 130.455 176.417 1.00 161.98 ? 120  GLU A O    1 
ATOM   1679 C CB   . GLU A 1 105 ? 205.902 129.875 178.573 1.00 159.08 ? 120  GLU A CB   1 
ATOM   1680 C CG   . GLU A 1 105 ? 206.989 128.956 179.156 1.00 166.81 ? 120  GLU A CG   1 
ATOM   1681 C CD   . GLU A 1 105 ? 206.698 128.408 180.564 1.00 170.36 ? 120  GLU A CD   1 
ATOM   1682 O OE1  . GLU A 1 105 ? 205.737 128.867 181.217 1.00 168.46 ? 120  GLU A OE1  1 
ATOM   1683 O OE2  . GLU A 1 105 ? 207.479 127.546 181.037 1.00 171.86 ? 120  GLU A OE2  1 
ATOM   1684 H H    . GLU A 1 105 ? 204.930 128.202 176.528 1.00 160.50 ? 120  GLU A H    1 
ATOM   1685 H HA   . GLU A 1 105 ? 204.064 128.996 179.280 1.00 159.97 ? 120  GLU A HA   1 
ATOM   1686 H HB2  . GLU A 1 105 ? 206.281 130.254 177.625 1.00 160.56 ? 120  GLU A HB2  1 
ATOM   1687 H HB3  . GLU A 1 105 ? 205.783 130.735 179.233 1.00 160.63 ? 120  GLU A HB3  1 
ATOM   1688 H HG2  . GLU A 1 105 ? 207.159 128.127 178.468 1.00 161.70 ? 120  GLU A HG2  1 
ATOM   1689 H HG3  . GLU A 1 105 ? 207.915 129.530 179.196 1.00 161.41 ? 120  GLU A HG3  1 
ATOM   1690 N N    . PHE A 1 106 ? 202.858 131.061 178.392 1.00 134.20 ? 121  PHE A N    1 
ATOM   1691 C CA   . PHE A 1 106 ? 202.284 132.341 177.962 1.00 135.81 ? 121  PHE A CA   1 
ATOM   1692 C C    . PHE A 1 106 ? 201.863 133.172 179.179 1.00 137.71 ? 121  PHE A C    1 
ATOM   1693 O O    . PHE A 1 106 ? 201.835 132.672 180.301 1.00 145.30 ? 121  PHE A O    1 
ATOM   1694 C CB   . PHE A 1 106 ? 201.133 132.159 176.960 1.00 135.31 ? 121  PHE A CB   1 
ATOM   1695 C CG   . PHE A 1 106 ? 199.965 131.296 177.374 1.00 132.59 ? 121  PHE A CG   1 
ATOM   1696 C CD1  . PHE A 1 106 ? 198.874 131.858 178.053 1.00 132.04 ? 121  PHE A CD1  1 
ATOM   1697 C CD2  . PHE A 1 106 ? 199.917 129.950 176.980 1.00 128.85 ? 121  PHE A CD2  1 
ATOM   1698 C CE1  . PHE A 1 106 ? 197.736 131.083 178.327 1.00 131.04 ? 121  PHE A CE1  1 
ATOM   1699 C CE2  . PHE A 1 106 ? 198.775 129.178 177.244 1.00 130.07 ? 121  PHE A CE2  1 
ATOM   1700 C CZ   . PHE A 1 106 ? 197.682 129.746 177.909 1.00 132.25 ? 121  PHE A CZ   1 
ATOM   1701 H H    . PHE A 1 106 ? 202.816 130.872 179.384 1.00 136.63 ? 121  PHE A H    1 
ATOM   1702 H HA   . PHE A 1 106 ? 203.066 132.906 177.454 1.00 136.12 ? 121  PHE A HA   1 
ATOM   1703 H HB2  . PHE A 1 106 ? 200.748 133.144 176.692 1.00 136.10 ? 121  PHE A HB2  1 
ATOM   1704 H HB3  . PHE A 1 106 ? 201.544 131.747 176.038 1.00 137.06 ? 121  PHE A HB3  1 
ATOM   1705 H HD1  . PHE A 1 106 ? 198.895 132.897 178.347 1.00 135.28 ? 121  PHE A HD1  1 
ATOM   1706 H HD2  . PHE A 1 106 ? 200.749 129.515 176.447 1.00 135.80 ? 121  PHE A HD2  1 
ATOM   1707 H HE1  . PHE A 1 106 ? 196.895 131.520 178.844 1.00 135.59 ? 121  PHE A HE1  1 
ATOM   1708 H HE2  . PHE A 1 106 ? 198.730 128.148 176.921 1.00 135.35 ? 121  PHE A HE2  1 
ATOM   1709 H HZ   . PHE A 1 106 ? 196.802 129.152 178.103 1.00 136.30 ? 121  PHE A HZ   1 
ATOM   1710 N N    . SER A 1 107 ? 201.583 134.461 178.997 1.00 139.93 ? 122  SER A N    1 
ATOM   1711 C CA   . SER A 1 107 ? 201.261 135.361 180.108 1.00 144.88 ? 122  SER A CA   1 
ATOM   1712 C C    . SER A 1 107 ? 199.970 134.985 180.845 1.00 146.01 ? 122  SER A C    1 
ATOM   1713 O O    . SER A 1 107 ? 198.935 134.759 180.227 1.00 149.27 ? 122  SER A O    1 
ATOM   1714 C CB   . SER A 1 107 ? 201.117 136.793 179.595 1.00 146.05 ? 122  SER A CB   1 
ATOM   1715 O OG   . SER A 1 107 ? 202.282 137.204 178.907 1.00 146.37 ? 122  SER A OG   1 
ATOM   1716 H H    . SER A 1 107 ? 201.658 134.859 178.071 1.00 143.30 ? 122  SER A H    1 
ATOM   1717 H HA   . SER A 1 107 ? 202.083 135.338 180.823 1.00 144.19 ? 122  SER A HA   1 
ATOM   1718 H HB2  . SER A 1 107 ? 200.266 136.849 178.915 1.00 144.79 ? 122  SER A HB2  1 
ATOM   1719 H HB3  . SER A 1 107 ? 200.935 137.460 180.438 1.00 145.17 ? 122  SER A HB3  1 
ATOM   1720 H HG   . SER A 1 107 ? 202.968 137.365 179.558 1.00 144.68 ? 122  SER A HG   1 
ATOM   1721 N N    . THR A 1 108 ? 199.996 135.005 182.174 1.00 132.71 ? 123  THR A N    1 
ATOM   1722 C CA   . THR A 1 108 ? 198.783 134.991 183.004 1.00 131.55 ? 123  THR A CA   1 
ATOM   1723 C C    . THR A 1 108 ? 197.988 136.272 182.814 1.00 129.51 ? 123  THR A C    1 
ATOM   1724 O O    . THR A 1 108 ? 198.578 137.345 182.731 1.00 136.82 ? 123  THR A O    1 
ATOM   1725 C CB   . THR A 1 108 ? 199.168 134.858 184.480 1.00 141.70 ? 123  THR A CB   1 
ATOM   1726 O OG1  . THR A 1 108 ? 199.671 133.569 184.673 1.00 150.56 ? 123  THR A OG1  1 
ATOM   1727 C CG2  . THR A 1 108 ? 198.044 135.041 185.493 1.00 142.81 ? 123  THR A CG2  1 
ATOM   1728 H H    . THR A 1 108 ? 200.881 135.150 182.639 1.00 137.84 ? 123  THR A H    1 
ATOM   1729 H HA   . THR A 1 108 ? 198.158 134.143 182.725 1.00 137.73 ? 123  THR A HA   1 
ATOM   1730 H HB   . THR A 1 108 ? 199.952 135.578 184.709 1.00 138.37 ? 123  THR A HB   1 
ATOM   1731 H HG1  . THR A 1 108 ? 199.842 133.450 185.611 1.00 140.15 ? 123  THR A HG1  1 
ATOM   1732 H HG21 . THR A 1 108 ? 198.416 134.817 186.493 1.00 139.65 ? 123  THR A HG21 1 
ATOM   1733 H HG22 . THR A 1 108 ? 197.214 134.372 185.267 1.00 139.40 ? 123  THR A HG22 1 
ATOM   1734 H HG23 . THR A 1 108 ? 197.691 136.072 185.485 1.00 138.25 ? 123  THR A HG23 1 
ATOM   1735 N N    . ILE A 1 109 ? 196.661 136.201 182.830 1.00 121.58 ? 124  ILE A N    1 
ATOM   1736 C CA   . ILE A 1 109 ? 195.793 137.385 182.903 1.00 127.22 ? 124  ILE A CA   1 
ATOM   1737 C C    . ILE A 1 109 ? 195.032 137.395 184.224 1.00 128.37 ? 124  ILE A C    1 
ATOM   1738 O O    . ILE A 1 109 ? 194.581 136.350 184.689 1.00 141.72 ? 124  ILE A O    1 
ATOM   1739 C CB   . ILE A 1 109 ? 194.879 137.498 181.669 1.00 128.35 ? 124  ILE A CB   1 
ATOM   1740 C CG1  . ILE A 1 109 ? 194.083 138.814 181.692 1.00 131.21 ? 124  ILE A CG1  1 
ATOM   1741 C CG2  . ILE A 1 109 ? 193.936 136.299 181.539 1.00 126.37 ? 124  ILE A CG2  1 
ATOM   1742 C CD1  . ILE A 1 109 ? 193.392 139.132 180.366 1.00 127.97 ? 124  ILE A CD1  1 
ATOM   1743 H H    . ILE A 1 109 ? 196.230 135.295 182.951 1.00 129.89 ? 124  ILE A H    1 
ATOM   1744 H HA   . ILE A 1 109 ? 196.417 138.279 182.902 1.00 130.84 ? 124  ILE A HA   1 
ATOM   1745 H HB   . ILE A 1 109 ? 195.524 137.516 180.790 1.00 130.49 ? 124  ILE A HB   1 
ATOM   1746 H HG12 . ILE A 1 109 ? 193.331 138.783 182.481 1.00 130.55 ? 124  ILE A HG12 1 
ATOM   1747 H HG13 . ILE A 1 109 ? 194.770 139.633 181.902 1.00 131.19 ? 124  ILE A HG13 1 
ATOM   1748 H HG21 . ILE A 1 109 ? 194.518 135.378 181.505 1.00 130.27 ? 124  ILE A HG21 1 
ATOM   1749 H HG22 . ILE A 1 109 ? 193.363 136.361 180.614 1.00 130.32 ? 124  ILE A HG22 1 
ATOM   1750 H HG23 . ILE A 1 109 ? 193.242 136.266 182.378 1.00 129.61 ? 124  ILE A HG23 1 
ATOM   1751 H HD11 . ILE A 1 109 ? 192.938 140.121 180.428 1.00 130.23 ? 124  ILE A HD11 1 
ATOM   1752 H HD12 . ILE A 1 109 ? 194.120 139.128 179.555 1.00 130.30 ? 124  ILE A HD12 1 
ATOM   1753 H HD13 . ILE A 1 109 ? 192.606 138.406 180.159 1.00 130.04 ? 124  ILE A HD13 1 
ATOM   1754 N N    . VAL A 1 110 ? 194.887 138.570 184.831 1.00 124.13 ? 125  VAL A N    1 
ATOM   1755 C CA   . VAL A 1 110 ? 194.037 138.788 186.004 1.00 124.21 ? 125  VAL A CA   1 
ATOM   1756 C C    . VAL A 1 110 ? 192.929 139.761 185.651 1.00 127.90 ? 125  VAL A C    1 
ATOM   1757 O O    . VAL A 1 110 ? 193.157 140.732 184.935 1.00 137.66 ? 125  VAL A O    1 
ATOM   1758 C CB   . VAL A 1 110 ? 194.823 139.245 187.241 1.00 125.17 ? 125  VAL A CB   1 
ATOM   1759 C CG1  . VAL A 1 110 ? 195.973 138.284 187.529 1.00 129.47 ? 125  VAL A CG1  1 
ATOM   1760 C CG2  . VAL A 1 110 ? 195.417 140.646 187.131 1.00 134.87 ? 125  VAL A CG2  1 
ATOM   1761 H H    . VAL A 1 110 ? 195.291 139.389 184.400 1.00 131.42 ? 125  VAL A H    1 
ATOM   1762 H HA   . VAL A 1 110 ? 193.564 137.842 186.269 1.00 131.66 ? 125  VAL A HA   1 
ATOM   1763 H HB   . VAL A 1 110 ? 194.145 139.231 188.093 1.00 130.66 ? 125  VAL A HB   1 
ATOM   1764 H HG11 . VAL A 1 110 ? 195.604 137.258 187.506 1.00 132.16 ? 125  VAL A HG11 1 
ATOM   1765 H HG12 . VAL A 1 110 ? 196.392 138.492 188.513 1.00 131.72 ? 125  VAL A HG12 1 
ATOM   1766 H HG13 . VAL A 1 110 ? 196.755 138.389 186.776 1.00 130.75 ? 125  VAL A HG13 1 
ATOM   1767 H HG21 . VAL A 1 110 ? 194.626 141.385 187.007 1.00 132.91 ? 125  VAL A HG21 1 
ATOM   1768 H HG22 . VAL A 1 110 ? 195.965 140.885 188.042 1.00 132.53 ? 125  VAL A HG22 1 
ATOM   1769 H HG23 . VAL A 1 110 ? 196.097 140.695 186.281 1.00 131.56 ? 125  VAL A HG23 1 
ATOM   1770 N N    . ILE A 1 111 ? 191.721 139.509 186.138 1.00 127.35 ? 126  ILE A N    1 
ATOM   1771 C CA   . ILE A 1 111 ? 190.538 140.336 185.895 1.00 126.62 ? 126  ILE A CA   1 
ATOM   1772 C C    . ILE A 1 111 ? 189.886 140.604 187.249 1.00 130.08 ? 126  ILE A C    1 
ATOM   1773 O O    . ILE A 1 111 ? 189.751 139.688 188.055 1.00 138.19 ? 126  ILE A O    1 
ATOM   1774 C CB   . ILE A 1 111 ? 189.569 139.656 184.904 1.00 127.72 ? 126  ILE A CB   1 
ATOM   1775 C CG1  . ILE A 1 111 ? 190.258 139.201 183.600 1.00 130.42 ? 126  ILE A CG1  1 
ATOM   1776 C CG2  . ILE A 1 111 ? 188.415 140.614 184.589 1.00 127.05 ? 126  ILE A CG2  1 
ATOM   1777 C CD1  . ILE A 1 111 ? 189.354 138.380 182.681 1.00 133.62 ? 126  ILE A CD1  1 
ATOM   1778 H H    . ILE A 1 111 ? 191.608 138.700 186.731 1.00 131.47 ? 126  ILE A H    1 
ATOM   1779 H HA   . ILE A 1 111 ? 190.841 141.294 185.471 1.00 131.11 ? 126  ILE A HA   1 
ATOM   1780 H HB   . ILE A 1 111 ? 189.154 138.771 185.388 1.00 131.59 ? 126  ILE A HB   1 
ATOM   1781 H HG12 . ILE A 1 111 ? 190.623 140.071 183.055 1.00 131.59 ? 126  ILE A HG12 1 
ATOM   1782 H HG13 . ILE A 1 111 ? 191.111 138.567 183.841 1.00 131.67 ? 126  ILE A HG13 1 
ATOM   1783 H HG21 . ILE A 1 111 ? 187.675 140.128 183.954 1.00 131.09 ? 126  ILE A HG21 1 
ATOM   1784 H HG22 . ILE A 1 111 ? 187.906 140.918 185.504 1.00 130.78 ? 126  ILE A HG22 1 
ATOM   1785 H HG23 . ILE A 1 111 ? 188.791 141.501 184.080 1.00 131.22 ? 126  ILE A HG23 1 
ATOM   1786 H HD11 . ILE A 1 111 ? 189.949 137.985 181.857 1.00 131.77 ? 126  ILE A HD11 1 
ATOM   1787 H HD12 . ILE A 1 111 ? 188.560 138.998 182.264 1.00 131.71 ? 126  ILE A HD12 1 
ATOM   1788 H HD13 . ILE A 1 111 ? 188.924 137.548 183.238 1.00 132.20 ? 126  ILE A HD13 1 
ATOM   1789 N N    . GLY A 1 112 ? 189.493 141.837 187.543 1.00 137.59 ? 127  GLY A N    1 
ATOM   1790 C CA   . GLY A 1 112 ? 189.036 142.201 188.880 1.00 139.63 ? 127  GLY A CA   1 
ATOM   1791 C C    . GLY A 1 112 ? 188.448 143.603 188.959 1.00 142.28 ? 127  GLY A C    1 
ATOM   1792 O O    . GLY A 1 112 ? 187.973 144.161 187.968 1.00 148.52 ? 127  GLY A O    1 
ATOM   1793 H H    . GLY A 1 112 ? 189.587 142.566 186.850 1.00 141.21 ? 127  GLY A H    1 
ATOM   1794 H HA2  . GLY A 1 112 ? 188.278 141.496 189.222 1.00 141.52 ? 127  GLY A HA2  1 
ATOM   1795 H HA3  . GLY A 1 112 ? 189.883 142.140 189.563 1.00 140.73 ? 127  GLY A HA3  1 
ATOM   1796 N N    . SER A 1 113 ? 188.485 144.183 190.154 1.00 138.12 ? 128  SER A N    1 
ATOM   1797 C CA   . SER A 1 113 ? 188.092 145.569 190.392 1.00 142.04 ? 128  SER A CA   1 
ATOM   1798 C C    . SER A 1 113 ? 189.168 146.327 191.169 1.00 142.44 ? 128  SER A C    1 
ATOM   1799 O O    . SER A 1 113 ? 189.973 147.026 190.565 1.00 140.87 ? 128  SER A O    1 
ATOM   1800 C CB   . SER A 1 113 ? 186.705 145.631 191.032 1.00 143.26 ? 128  SER A CB   1 
ATOM   1801 O OG   . SER A 1 113 ? 186.696 144.927 192.262 1.00 143.44 ? 128  SER A OG   1 
ATOM   1802 H H    . SER A 1 113 ? 188.809 143.641 190.942 1.00 141.22 ? 128  SER A H    1 
ATOM   1803 H HA   . SER A 1 113 ? 188.018 146.078 189.430 1.00 142.27 ? 128  SER A HA   1 
ATOM   1804 H HB2  . SER A 1 113 ? 186.428 146.672 191.200 1.00 142.61 ? 128  SER A HB2  1 
ATOM   1805 H HB3  . SER A 1 113 ? 185.982 145.182 190.352 1.00 141.72 ? 128  SER A HB3  1 
ATOM   1806 H HG   . SER A 1 113 ? 185.782 144.839 192.543 1.00 142.22 ? 128  SER A HG   1 
ATOM   1807 N N    . VAL A 1 114 ? 189.234 146.175 192.490 1.00 147.24 ? 129  VAL A N    1 
ATOM   1808 C CA   . VAL A 1 114 ? 190.242 146.841 193.335 1.00 149.83 ? 129  VAL A CA   1 
ATOM   1809 C C    . VAL A 1 114 ? 191.483 145.991 193.600 1.00 151.76 ? 129  VAL A C    1 
ATOM   1810 O O    . VAL A 1 114 ? 192.482 146.519 194.072 1.00 149.60 ? 129  VAL A O    1 
ATOM   1811 C CB   . VAL A 1 114 ? 189.626 147.340 194.653 1.00 153.13 ? 129  VAL A CB   1 
ATOM   1812 C CG1  . VAL A 1 114 ? 188.554 148.397 194.383 1.00 150.95 ? 129  VAL A CG1  1 
ATOM   1813 C CG2  . VAL A 1 114 ? 189.001 146.226 195.493 1.00 151.22 ? 129  VAL A CG2  1 
ATOM   1814 H H    . VAL A 1 114 ? 188.502 145.635 192.928 1.00 148.74 ? 129  VAL A H    1 
ATOM   1815 H HA   . VAL A 1 114 ? 190.602 147.728 192.814 1.00 148.92 ? 129  VAL A HA   1 
ATOM   1816 H HB   . VAL A 1 114 ? 190.410 147.813 195.244 1.00 150.23 ? 129  VAL A HB   1 
ATOM   1817 H HG11 . VAL A 1 114 ? 188.979 149.208 193.791 1.00 149.47 ? 129  VAL A HG11 1 
ATOM   1818 H HG12 . VAL A 1 114 ? 188.197 148.806 195.328 1.00 149.83 ? 129  VAL A HG12 1 
ATOM   1819 H HG13 . VAL A 1 114 ? 187.712 147.963 193.843 1.00 149.35 ? 129  VAL A HG13 1 
ATOM   1820 H HG21 . VAL A 1 114 ? 189.739 145.456 195.713 1.00 149.70 ? 129  VAL A HG21 1 
ATOM   1821 H HG22 . VAL A 1 114 ? 188.650 146.641 196.438 1.00 149.64 ? 129  VAL A HG22 1 
ATOM   1822 H HG23 . VAL A 1 114 ? 188.153 145.781 194.973 1.00 149.24 ? 129  VAL A HG23 1 
ATOM   1823 N N    . PHE A 1 115 ? 191.449 144.688 193.303 1.00 146.50 ? 130  PHE A N    1 
ATOM   1824 C CA   . PHE A 1 115 ? 192.548 143.738 193.542 1.00 143.82 ? 130  PHE A CA   1 
ATOM   1825 C C    . PHE A 1 115 ? 192.960 143.583 195.024 1.00 146.92 ? 130  PHE A C    1 
ATOM   1826 O O    . PHE A 1 115 ? 194.034 143.075 195.328 1.00 148.33 ? 130  PHE A O    1 
ATOM   1827 C CB   . PHE A 1 115 ? 193.724 144.036 192.596 1.00 141.87 ? 130  PHE A CB   1 
ATOM   1828 C CG   . PHE A 1 115 ? 193.365 144.058 191.125 1.00 141.16 ? 130  PHE A CG   1 
ATOM   1829 C CD1  . PHE A 1 115 ? 193.170 142.853 190.434 1.00 143.66 ? 130  PHE A CD1  1 
ATOM   1830 C CD2  . PHE A 1 115 ? 193.212 145.281 190.453 1.00 141.81 ? 130  PHE A CD2  1 
ATOM   1831 C CE1  . PHE A 1 115 ? 192.827 142.869 189.073 1.00 142.13 ? 130  PHE A CE1  1 
ATOM   1832 C CE2  . PHE A 1 115 ? 192.876 145.296 189.092 1.00 139.62 ? 130  PHE A CE2  1 
ATOM   1833 C CZ   . PHE A 1 115 ? 192.684 144.091 188.400 1.00 138.89 ? 130  PHE A CZ   1 
ATOM   1834 H H    . PHE A 1 115 ? 190.605 144.330 192.881 1.00 143.83 ? 130  PHE A H    1 
ATOM   1835 H HA   . PHE A 1 115 ? 192.173 142.755 193.257 1.00 143.42 ? 130  PHE A HA   1 
ATOM   1836 H HB2  . PHE A 1 115 ? 194.166 144.994 192.868 1.00 143.72 ? 130  PHE A HB2  1 
ATOM   1837 H HB3  . PHE A 1 115 ? 194.494 143.279 192.739 1.00 144.32 ? 130  PHE A HB3  1 
ATOM   1838 H HD1  . PHE A 1 115 ? 193.279 141.911 190.950 1.00 143.93 ? 130  PHE A HD1  1 
ATOM   1839 H HD2  . PHE A 1 115 ? 193.350 146.213 190.981 1.00 144.33 ? 130  PHE A HD2  1 
ATOM   1840 H HE1  . PHE A 1 115 ? 192.677 141.940 188.544 1.00 143.49 ? 130  PHE A HE1  1 
ATOM   1841 H HE2  . PHE A 1 115 ? 192.762 146.240 188.579 1.00 143.34 ? 130  PHE A HE2  1 
ATOM   1842 H HZ   . PHE A 1 115 ? 192.423 144.103 187.352 1.00 143.35 ? 130  PHE A HZ   1 
ATOM   1843 N N    . ILE A 1 116 ? 192.108 144.000 195.964 1.00 151.56 ? 131  ILE A N    1 
ATOM   1844 C CA   . ILE A 1 116 ? 192.283 143.827 197.415 1.00 145.52 ? 131  ILE A CA   1 
ATOM   1845 C C    . ILE A 1 116 ? 191.574 142.546 197.865 1.00 148.04 ? 131  ILE A C    1 
ATOM   1846 O O    . ILE A 1 116 ? 190.505 142.219 197.345 1.00 153.86 ? 131  ILE A O    1 
ATOM   1847 C CB   . ILE A 1 116 ? 191.712 145.042 198.182 1.00 146.01 ? 131  ILE A CB   1 
ATOM   1848 C CG1  . ILE A 1 116 ? 192.319 146.371 197.690 1.00 151.08 ? 131  ILE A CG1  1 
ATOM   1849 C CG2  . ILE A 1 116 ? 191.913 144.909 199.701 1.00 148.11 ? 131  ILE A CG2  1 
ATOM   1850 C CD1  . ILE A 1 116 ? 191.650 147.628 198.261 1.00 148.62 ? 131  ILE A CD1  1 
ATOM   1851 H H    . ILE A 1 116 ? 191.232 144.388 195.645 1.00 150.14 ? 131  ILE A H    1 
ATOM   1852 H HA   . ILE A 1 116 ? 193.344 143.742 197.648 1.00 148.75 ? 131  ILE A HA   1 
ATOM   1853 H HB   . ILE A 1 116 ? 190.639 145.082 197.990 1.00 149.01 ? 131  ILE A HB   1 
ATOM   1854 H HG12 . ILE A 1 116 ? 193.383 146.393 197.927 1.00 149.56 ? 131  ILE A HG12 1 
ATOM   1855 H HG13 . ILE A 1 116 ? 192.216 146.439 196.607 1.00 150.19 ? 131  ILE A HG13 1 
ATOM   1856 H HG21 . ILE A 1 116 ? 191.384 144.043 200.101 1.00 149.56 ? 131  ILE A HG21 1 
ATOM   1857 H HG22 . ILE A 1 116 ? 191.502 145.777 200.219 1.00 149.84 ? 131  ILE A HG22 1 
ATOM   1858 H HG23 . ILE A 1 116 ? 192.974 144.831 199.935 1.00 149.12 ? 131  ILE A HG23 1 
ATOM   1859 H HD11 . ILE A 1 116 ? 192.025 148.506 197.734 1.00 148.89 ? 131  ILE A HD11 1 
ATOM   1860 H HD12 . ILE A 1 116 ? 190.570 147.571 198.127 1.00 149.48 ? 131  ILE A HD12 1 
ATOM   1861 H HD13 . ILE A 1 116 ? 191.883 147.744 199.320 1.00 149.12 ? 131  ILE A HD13 1 
ATOM   1862 N N    . ASN A 1 117 ? 192.092 141.863 198.886 1.00 147.70 ? 132  ASN A N    1 
ATOM   1863 C CA   . ASN A 1 117 ? 191.522 140.637 199.460 1.00 149.01 ? 132  ASN A CA   1 
ATOM   1864 C C    . ASN A 1 117 ? 190.140 140.771 200.142 1.00 148.80 ? 132  ASN A C    1 
ATOM   1865 O O    . ASN A 1 117 ? 189.709 139.848 200.826 1.00 150.13 ? 132  ASN A O    1 
ATOM   1866 C CB   . ASN A 1 117 ? 192.559 139.991 200.393 1.00 151.38 ? 132  ASN A CB   1 
ATOM   1867 C CG   . ASN A 1 117 ? 192.821 140.761 201.672 1.00 151.49 ? 132  ASN A CG   1 
ATOM   1868 O OD1  . ASN A 1 117 ? 192.039 141.625 202.055 1.00 152.16 ? 132  ASN A OD1  1 
ATOM   1869 N ND2  . ASN A 1 117 ? 193.951 140.506 202.308 1.00 153.03 ? 132  ASN A ND2  1 
ATOM   1870 H H    . ASN A 1 117 ? 192.944 142.219 199.299 1.00 150.14 ? 132  ASN A H    1 
ATOM   1871 H HA   . ASN A 1 117 ? 191.368 139.949 198.629 1.00 150.79 ? 132  ASN A HA   1 
ATOM   1872 H HB2  . ASN A 1 117 ? 192.221 138.993 200.673 1.00 151.02 ? 132  ASN A HB2  1 
ATOM   1873 H HB3  . ASN A 1 117 ? 193.496 139.874 199.847 1.00 150.89 ? 132  ASN A HB3  1 
ATOM   1874 H HD21 . ASN A 1 117 ? 194.585 139.823 201.920 1.00 151.41 ? 132  ASN A HD21 1 
ATOM   1875 N N    . ASN A 1 118 ? 189.421 141.879 199.957 1.00 154.32 ? 133  ASN A N    1 
ATOM   1876 C CA   . ASN A 1 118 ? 187.995 142.008 200.282 1.00 151.75 ? 133  ASN A CA   1 
ATOM   1877 C C    . ASN A 1 118 ? 187.114 142.030 199.014 1.00 153.93 ? 133  ASN A C    1 
ATOM   1878 O O    . ASN A 1 118 ? 185.950 142.425 199.062 1.00 152.50 ? 133  ASN A O    1 
ATOM   1879 C CB   . ASN A 1 118 ? 187.779 143.202 201.223 1.00 151.21 ? 133  ASN A CB   1 
ATOM   1880 C CG   . ASN A 1 118 ? 188.106 144.545 200.608 1.00 157.42 ? 133  ASN A CG   1 
ATOM   1881 O OD1  . ASN A 1 118 ? 188.395 144.673 199.430 1.00 157.51 ? 133  ASN A OD1  1 
ATOM   1882 N ND2  . ASN A 1 118 ? 188.086 145.593 201.395 1.00 156.41 ? 133  ASN A ND2  1 
ATOM   1883 H H    . ASN A 1 118 ? 189.826 142.613 199.395 1.00 154.07 ? 133  ASN A H    1 
ATOM   1884 H HA   . ASN A 1 118 ? 187.679 141.121 200.829 1.00 152.99 ? 133  ASN A HA   1 
ATOM   1885 H HB2  . ASN A 1 118 ? 186.737 143.221 201.543 1.00 153.35 ? 133  ASN A HB2  1 
ATOM   1886 H HB3  . ASN A 1 118 ? 188.396 143.069 202.111 1.00 152.75 ? 133  ASN A HB3  1 
ATOM   1887 H HD21 . ASN A 1 118 ? 187.853 145.490 202.372 1.00 153.35 ? 133  ASN A HD21 1 
ATOM   1888 H HD22 . ASN A 1 118 ? 188.305 146.495 200.998 1.00 153.70 ? 133  ASN A HD22 1 
ATOM   1889 N N    . SER A 1 119 ? 187.674 141.618 197.874 1.00 162.82 ? 134  SER A N    1 
ATOM   1890 C CA   . SER A 1 119 ? 187.018 141.510 196.568 1.00 162.12 ? 134  SER A CA   1 
ATOM   1891 C C    . SER A 1 119 ? 187.578 140.315 195.798 1.00 160.28 ? 134  SER A C    1 
ATOM   1892 O O    . SER A 1 119 ? 188.720 139.921 196.025 1.00 164.98 ? 134  SER A O    1 
ATOM   1893 C CB   . SER A 1 119 ? 187.250 142.796 195.774 1.00 161.01 ? 134  SER A CB   1 
ATOM   1894 O OG   . SER A 1 119 ? 188.610 142.904 195.393 1.00 161.79 ? 134  SER A OG   1 
ATOM   1895 H H    . SER A 1 119 ? 188.643 141.335 197.904 1.00 160.59 ? 134  SER A H    1 
ATOM   1896 H HA   . SER A 1 119 ? 185.946 141.369 196.705 1.00 160.74 ? 134  SER A HA   1 
ATOM   1897 H HB2  . SER A 1 119 ? 186.630 142.784 194.878 1.00 159.99 ? 134  SER A HB2  1 
ATOM   1898 H HB3  . SER A 1 119 ? 186.968 143.656 196.382 1.00 160.50 ? 134  SER A HB3  1 
ATOM   1899 H HG   . SER A 1 119 ? 189.154 142.665 196.146 1.00 160.84 ? 134  SER A HG   1 
ATOM   1900 N N    . TYR A 1 120 ? 186.809 139.725 194.886 1.00 144.63 ? 135  TYR A N    1 
ATOM   1901 C CA   . TYR A 1 120 ? 187.274 138.570 194.118 1.00 143.58 ? 135  TYR A CA   1 
ATOM   1902 C C    . TYR A 1 120 ? 188.043 139.000 192.871 1.00 143.80 ? 135  TYR A C    1 
ATOM   1903 O O    . TYR A 1 120 ? 187.560 139.810 192.086 1.00 146.00 ? 135  TYR A O    1 
ATOM   1904 C CB   . TYR A 1 120 ? 186.101 137.657 193.762 1.00 143.53 ? 135  TYR A CB   1 
ATOM   1905 C CG   . TYR A 1 120 ? 185.422 137.084 194.985 1.00 144.76 ? 135  TYR A CG   1 
ATOM   1906 C CD1  . TYR A 1 120 ? 185.946 135.942 195.613 1.00 145.30 ? 135  TYR A CD1  1 
ATOM   1907 C CD2  . TYR A 1 120 ? 184.290 137.723 195.516 1.00 148.39 ? 135  TYR A CD2  1 
ATOM   1908 C CE1  . TYR A 1 120 ? 185.340 135.436 196.777 1.00 149.31 ? 135  TYR A CE1  1 
ATOM   1909 C CE2  . TYR A 1 120 ? 183.679 137.220 196.674 1.00 149.91 ? 135  TYR A CE2  1 
ATOM   1910 C CZ   . TYR A 1 120 ? 184.200 136.075 197.305 1.00 151.32 ? 135  TYR A CZ   1 
ATOM   1911 O OH   . TYR A 1 120 ? 183.584 135.585 198.412 1.00 153.81 ? 135  TYR A OH   1 
ATOM   1912 H H    . TYR A 1 120 ? 185.880 140.080 194.711 1.00 148.01 ? 135  TYR A H    1 
ATOM   1913 H HA   . TYR A 1 120 ? 187.947 137.983 194.742 1.00 147.89 ? 135  TYR A HA   1 
ATOM   1914 H HB2  . TYR A 1 120 ? 185.375 138.212 193.168 1.00 147.77 ? 135  TYR A HB2  1 
ATOM   1915 H HB3  . TYR A 1 120 ? 186.468 136.832 193.150 1.00 147.52 ? 135  TYR A HB3  1 
ATOM   1916 H HD1  . TYR A 1 120 ? 186.813 135.450 195.196 1.00 147.70 ? 135  TYR A HD1  1 
ATOM   1917 H HD2  . TYR A 1 120 ? 183.884 138.600 195.032 1.00 148.42 ? 135  TYR A HD2  1 
ATOM   1918 H HE1  . TYR A 1 120 ? 185.743 134.556 197.256 1.00 148.36 ? 135  TYR A HE1  1 
ATOM   1919 H HE2  . TYR A 1 120 ? 182.804 137.702 197.085 1.00 148.52 ? 135  TYR A HE2  1 
ATOM   1920 H HH   . TYR A 1 120 ? 183.921 134.723 198.663 1.00 148.36 ? 135  TYR A HH   1 
ATOM   1921 N N    . THR A 1 121 ? 189.223 138.422 192.668 1.00 144.34 ? 136  THR A N    1 
ATOM   1922 C CA   . THR A 1 121 ? 190.018 138.554 191.442 1.00 142.20 ? 136  THR A CA   1 
ATOM   1923 C C    . THR A 1 121 ? 189.978 137.232 190.693 1.00 141.90 ? 136  THR A C    1 
ATOM   1924 O O    . THR A 1 121 ? 190.278 136.193 191.277 1.00 144.55 ? 136  THR A O    1 
ATOM   1925 C CB   . THR A 1 121 ? 191.467 138.920 191.775 1.00 145.28 ? 136  THR A CB   1 
ATOM   1926 O OG1  . THR A 1 121 ? 191.492 140.158 192.444 1.00 146.54 ? 136  THR A OG1  1 
ATOM   1927 C CG2  . THR A 1 121 ? 192.344 139.069 190.540 1.00 145.41 ? 136  THR A CG2  1 
ATOM   1928 H H    . THR A 1 121 ? 189.543 137.749 193.350 1.00 145.00 ? 136  THR A H    1 
ATOM   1929 H HA   . THR A 1 121 ? 189.609 139.333 190.799 1.00 143.82 ? 136  THR A HA   1 
ATOM   1930 H HB   . THR A 1 121 ? 191.898 138.158 192.425 1.00 144.23 ? 136  THR A HB   1 
ATOM   1931 H HG1  . THR A 1 121 ? 190.990 140.049 193.255 1.00 144.92 ? 136  THR A HG1  1 
ATOM   1932 H HG21 . THR A 1 121 ? 193.335 139.412 190.838 1.00 143.88 ? 136  THR A HG21 1 
ATOM   1933 H HG22 . THR A 1 121 ? 192.452 138.107 190.040 1.00 144.40 ? 136  THR A HG22 1 
ATOM   1934 H HG23 . THR A 1 121 ? 191.901 139.790 189.853 1.00 144.21 ? 136  THR A HG23 1 
ATOM   1935 N N    . ILE A 1 122 ? 189.606 137.243 189.417 1.00 129.71 ? 137  ILE A N    1 
ATOM   1936 C CA   . ILE A 1 122 ? 189.742 136.084 188.535 1.00 124.99 ? 137  ILE A CA   1 
ATOM   1937 C C    . ILE A 1 122 ? 191.179 136.020 188.031 1.00 122.81 ? 137  ILE A C    1 
ATOM   1938 O O    . ILE A 1 122 ? 191.732 137.034 187.618 1.00 129.27 ? 137  ILE A O    1 
ATOM   1939 C CB   . ILE A 1 122 ? 188.745 136.159 187.369 1.00 120.39 ? 137  ILE A CB   1 
ATOM   1940 C CG1  . ILE A 1 122 ? 187.303 136.005 187.882 1.00 126.33 ? 137  ILE A CG1  1 
ATOM   1941 C CG2  . ILE A 1 122 ? 189.037 135.076 186.318 1.00 121.78 ? 137  ILE A CG2  1 
ATOM   1942 C CD1  . ILE A 1 122 ? 186.279 136.577 186.907 1.00 129.24 ? 137  ILE A CD1  1 
ATOM   1943 H H    . ILE A 1 122 ? 189.439 138.137 188.978 1.00 129.52 ? 137  ILE A H    1 
ATOM   1944 H HA   . ILE A 1 122 ? 189.532 135.176 189.100 1.00 128.78 ? 137  ILE A HA   1 
ATOM   1945 H HB   . ILE A 1 122 ? 188.850 137.136 186.896 1.00 127.77 ? 137  ILE A HB   1 
ATOM   1946 H HG12 . ILE A 1 122 ? 187.087 134.950 188.053 1.00 128.64 ? 137  ILE A HG12 1 
ATOM   1947 H HG13 . ILE A 1 122 ? 187.180 136.533 188.828 1.00 129.03 ? 137  ILE A HG13 1 
ATOM   1948 H HG21 . ILE A 1 122 ? 188.274 135.080 185.540 1.00 127.68 ? 137  ILE A HG21 1 
ATOM   1949 H HG22 . ILE A 1 122 ? 189.055 134.093 186.788 1.00 127.97 ? 137  ILE A HG22 1 
ATOM   1950 H HG23 . ILE A 1 122 ? 189.994 135.264 185.830 1.00 127.30 ? 137  ILE A HG23 1 
ATOM   1951 H HD11 . ILE A 1 122 ? 185.277 136.392 187.293 1.00 128.19 ? 137  ILE A HD11 1 
ATOM   1952 H HD12 . ILE A 1 122 ? 186.435 137.650 186.795 1.00 128.41 ? 137  ILE A HD12 1 
ATOM   1953 H HD13 . ILE A 1 122 ? 186.368 136.096 185.932 1.00 128.54 ? 137  ILE A HD13 1 
ATOM   1954 N N    . VAL A 1 123 ? 191.779 134.836 188.006 1.00 126.75 ? 138  VAL A N    1 
ATOM   1955 C CA   . VAL A 1 123 ? 193.128 134.607 187.482 1.00 127.26 ? 138  VAL A CA   1 
ATOM   1956 C C    . VAL A 1 123 ? 193.093 133.436 186.521 1.00 128.51 ? 138  VAL A C    1 
ATOM   1957 O O    . VAL A 1 123 ? 192.543 132.390 186.852 1.00 133.86 ? 138  VAL A O    1 
ATOM   1958 C CB   . VAL A 1 123 ? 194.124 134.331 188.616 1.00 132.40 ? 138  VAL A CB   1 
ATOM   1959 C CG1  . VAL A 1 123 ? 195.549 134.129 188.096 1.00 132.46 ? 138  VAL A CG1  1 
ATOM   1960 C CG2  . VAL A 1 123 ? 194.131 135.480 189.624 1.00 140.51 ? 138  VAL A CG2  1 
ATOM   1961 H H    . VAL A 1 123 ? 191.265 134.037 188.349 1.00 134.27 ? 138  VAL A H    1 
ATOM   1962 H HA   . VAL A 1 123 ? 193.470 135.487 186.936 1.00 133.97 ? 138  VAL A HA   1 
ATOM   1963 H HB   . VAL A 1 123 ? 193.828 133.423 189.143 1.00 133.61 ? 138  VAL A HB   1 
ATOM   1964 H HG11 . VAL A 1 123 ? 195.605 133.226 187.488 1.00 133.58 ? 138  VAL A HG11 1 
ATOM   1965 H HG12 . VAL A 1 123 ? 196.235 134.013 188.935 1.00 133.51 ? 138  VAL A HG12 1 
ATOM   1966 H HG13 . VAL A 1 123 ? 195.855 134.989 187.499 1.00 134.88 ? 138  VAL A HG13 1 
ATOM   1967 H HG21 . VAL A 1 123 ? 193.177 135.522 190.150 1.00 135.23 ? 138  VAL A HG21 1 
ATOM   1968 H HG22 . VAL A 1 123 ? 194.298 136.431 189.117 1.00 135.04 ? 138  VAL A HG22 1 
ATOM   1969 H HG23 . VAL A 1 123 ? 194.917 135.321 190.363 1.00 134.70 ? 138  VAL A HG23 1 
ATOM   1970 N N    . VAL A 1 124 ? 193.696 133.589 185.345 1.00 128.37 ? 139  VAL A N    1 
ATOM   1971 C CA   . VAL A 1 124 ? 193.831 132.529 184.340 1.00 126.49 ? 139  VAL A CA   1 
ATOM   1972 C C    . VAL A 1 124 ? 195.309 132.339 184.040 1.00 127.47 ? 139  VAL A C    1 
ATOM   1973 O O    . VAL A 1 124 ? 195.935 133.225 183.461 1.00 127.64 ? 139  VAL A O    1 
ATOM   1974 C CB   . VAL A 1 124 ? 193.052 132.901 183.071 1.00 122.74 ? 139  VAL A CB   1 
ATOM   1975 C CG1  . VAL A 1 124 ? 193.258 131.890 181.946 1.00 128.33 ? 139  VAL A CG1  1 
ATOM   1976 C CG2  . VAL A 1 124 ? 191.552 133.016 183.334 1.00 123.22 ? 139  VAL A CG2  1 
ATOM   1977 H H    . VAL A 1 124 ? 194.101 134.490 185.132 1.00 130.44 ? 139  VAL A H    1 
ATOM   1978 H HA   . VAL A 1 124 ? 193.432 131.589 184.720 1.00 129.22 ? 139  VAL A HA   1 
ATOM   1979 H HB   . VAL A 1 124 ? 193.399 133.872 182.719 1.00 128.57 ? 139  VAL A HB   1 
ATOM   1980 H HG11 . VAL A 1 124 ? 192.631 132.150 181.093 1.00 129.28 ? 139  VAL A HG11 1 
ATOM   1981 H HG12 . VAL A 1 124 ? 193.001 130.888 182.288 1.00 129.49 ? 139  VAL A HG12 1 
ATOM   1982 H HG13 . VAL A 1 124 ? 194.296 131.910 181.617 1.00 130.16 ? 139  VAL A HG13 1 
ATOM   1983 H HG21 . VAL A 1 124 ? 191.036 133.291 182.414 1.00 128.68 ? 139  VAL A HG21 1 
ATOM   1984 H HG22 . VAL A 1 124 ? 191.162 132.064 183.694 1.00 128.62 ? 139  VAL A HG22 1 
ATOM   1985 H HG23 . VAL A 1 124 ? 191.357 133.790 184.077 1.00 128.82 ? 139  VAL A HG23 1 
ATOM   1986 N N    . GLN A 1 125 ? 195.877 131.199 184.425 1.00 139.21 ? 140  GLN A N    1 
ATOM   1987 C CA   . GLN A 1 125 ? 197.317 130.954 184.364 1.00 136.81 ? 140  GLN A CA   1 
ATOM   1988 C C    . GLN A 1 125 ? 197.632 129.600 183.724 1.00 142.49 ? 140  GLN A C    1 
ATOM   1989 O O    . GLN A 1 125 ? 197.075 128.588 184.143 1.00 152.45 ? 140  GLN A O    1 
ATOM   1990 C CB   . GLN A 1 125 ? 197.872 131.022 185.789 1.00 135.91 ? 140  GLN A CB   1 
ATOM   1991 C CG   . GLN A 1 125 ? 199.353 130.634 185.880 1.00 141.19 ? 140  GLN A CG   1 
ATOM   1992 C CD   . GLN A 1 125 ? 199.952 131.186 187.156 1.00 144.32 ? 140  GLN A CD   1 
ATOM   1993 O OE1  . GLN A 1 125 ? 200.283 132.358 187.239 1.00 148.83 ? 140  GLN A OE1  1 
ATOM   1994 N NE2  . GLN A 1 125 ? 200.080 130.386 188.188 1.00 142.73 ? 140  GLN A NE2  1 
ATOM   1995 H H    . GLN A 1 125 ? 195.302 130.497 184.867 1.00 142.07 ? 140  GLN A H    1 
ATOM   1996 H HA   . GLN A 1 125 ? 197.795 131.746 183.790 1.00 141.00 ? 140  GLN A HA   1 
ATOM   1997 H HB2  . GLN A 1 125 ? 197.744 132.043 186.151 1.00 141.36 ? 140  GLN A HB2  1 
ATOM   1998 H HB3  . GLN A 1 125 ? 197.301 130.360 186.439 1.00 141.15 ? 140  GLN A HB3  1 
ATOM   1999 H HG2  . GLN A 1 125 ? 199.449 129.549 185.850 1.00 142.14 ? 140  GLN A HG2  1 
ATOM   2000 H HG3  . GLN A 1 125 ? 199.905 131.041 185.034 1.00 142.25 ? 140  GLN A HG3  1 
ATOM   2001 H HE21 . GLN A 1 125 ? 199.813 129.415 188.100 1.00 142.69 ? 140  GLN A HE21 1 
ATOM   2002 H HE22 . GLN A 1 125 ? 200.478 130.745 189.043 1.00 142.14 ? 140  GLN A HE22 1 
ATOM   2003 N N    . PRO A 1 126 ? 198.548 129.522 182.751 1.00 133.84 ? 141  PRO A N    1 
ATOM   2004 C CA   . PRO A 1 126 ? 198.990 128.255 182.208 1.00 135.93 ? 141  PRO A CA   1 
ATOM   2005 C C    . PRO A 1 126 ? 200.053 127.597 183.087 1.00 135.96 ? 141  PRO A C    1 
ATOM   2006 O O    . PRO A 1 126 ? 200.925 128.252 183.649 1.00 140.28 ? 141  PRO A O    1 
ATOM   2007 C CB   . PRO A 1 126 ? 199.539 128.593 180.832 1.00 135.08 ? 141  PRO A CB   1 
ATOM   2008 C CG   . PRO A 1 126 ? 200.123 129.982 181.040 1.00 141.36 ? 141  PRO A CG   1 
ATOM   2009 C CD   . PRO A 1 126 ? 199.158 130.622 182.033 1.00 137.77 ? 141  PRO A CD   1 
ATOM   2010 H HA   . PRO A 1 126 ? 198.145 127.576 182.092 1.00 139.71 ? 141  PRO A HA   1 
ATOM   2011 H HB2  . PRO A 1 126 ? 200.291 127.881 180.495 1.00 139.29 ? 141  PRO A HB2  1 
ATOM   2012 H HB3  . PRO A 1 126 ? 198.713 128.642 180.122 1.00 138.36 ? 141  PRO A HB3  1 
ATOM   2013 H HG2  . PRO A 1 126 ? 201.114 129.906 181.487 1.00 139.29 ? 141  PRO A HG2  1 
ATOM   2014 H HG3  . PRO A 1 126 ? 200.168 130.539 180.105 1.00 140.31 ? 141  PRO A HG3  1 
ATOM   2015 H HD2  . PRO A 1 126 ? 199.698 131.289 182.704 1.00 139.11 ? 141  PRO A HD2  1 
ATOM   2016 H HD3  . PRO A 1 126 ? 198.388 131.170 181.491 1.00 139.29 ? 141  PRO A HD3  1 
ATOM   2017 N N    . HIS A 1 127 ? 200.016 126.273 183.124 1.00 151.11 ? 142  HIS A N    1 
ATOM   2018 C CA   . HIS A 1 127 ? 200.987 125.376 183.734 1.00 153.49 ? 142  HIS A CA   1 
ATOM   2019 C C    . HIS A 1 127 ? 201.272 124.230 182.754 1.00 157.44 ? 142  HIS A C    1 
ATOM   2020 O O    . HIS A 1 127 ? 200.844 123.095 182.956 1.00 160.29 ? 142  HIS A O    1 
ATOM   2021 C CB   . HIS A 1 127 ? 200.442 124.874 185.079 1.00 156.76 ? 142  HIS A CB   1 
ATOM   2022 C CG   . HIS A 1 127 ? 200.419 125.918 186.153 1.00 160.75 ? 142  HIS A CG   1 
ATOM   2023 N ND1  . HIS A 1 127 ? 201.528 126.390 186.809 1.00 165.58 ? 142  HIS A ND1  1 
ATOM   2024 C CD2  . HIS A 1 127 ? 199.338 126.604 186.627 1.00 158.21 ? 142  HIS A CD2  1 
ATOM   2025 C CE1  . HIS A 1 127 ? 201.131 127.328 187.676 1.00 164.40 ? 142  HIS A CE1  1 
ATOM   2026 N NE2  . HIS A 1 127 ? 199.801 127.494 187.604 1.00 165.39 ? 142  HIS A NE2  1 
ATOM   2027 H H    . HIS A 1 127 ? 199.205 125.835 182.713 1.00 157.59 ? 142  HIS A H    1 
ATOM   2028 H HA   . HIS A 1 127 ? 201.925 125.901 183.909 1.00 157.39 ? 142  HIS A HA   1 
ATOM   2029 H HB2  . HIS A 1 127 ? 199.435 124.481 184.943 1.00 157.29 ? 142  HIS A HB2  1 
ATOM   2030 H HB3  . HIS A 1 127 ? 201.075 124.059 185.430 1.00 158.60 ? 142  HIS A HB3  1 
ATOM   2031 H HD1  . HIS A 1 127 ? 202.482 126.094 186.661 1.00 158.62 ? 142  HIS A HD1  1 
ATOM   2032 H HD2  . HIS A 1 127 ? 198.316 126.483 186.299 1.00 156.84 ? 142  HIS A HD2  1 
ATOM   2033 H HE1  . HIS A 1 127 ? 201.788 127.877 188.334 1.00 157.90 ? 142  HIS A HE1  1 
ATOM   2034 N N    . ASN A 1 128 ? 201.937 124.541 181.640 1.00 150.02 ? 143  ASN A N    1 
ATOM   2035 C CA   . ASN A 1 128 ? 202.399 123.576 180.638 1.00 150.39 ? 143  ASN A CA   1 
ATOM   2036 C C    . ASN A 1 128 ? 201.346 122.525 180.221 1.00 150.78 ? 143  ASN A C    1 
ATOM   2037 O O    . ASN A 1 128 ? 201.495 121.330 180.467 1.00 151.87 ? 143  ASN A O    1 
ATOM   2038 C CB   . ASN A 1 128 ? 203.715 122.956 181.131 1.00 153.61 ? 143  ASN A CB   1 
ATOM   2039 C CG   . ASN A 1 128 ? 204.354 122.118 180.045 1.00 158.34 ? 143  ASN A CG   1 
ATOM   2040 O OD1  . ASN A 1 128 ? 204.340 122.476 178.878 1.00 163.15 ? 143  ASN A OD1  1 
ATOM   2041 N ND2  . ASN A 1 128 ? 204.942 120.997 180.385 1.00 155.51 ? 143  ASN A ND2  1 
ATOM   2042 H H    . ASN A 1 128 ? 202.231 125.500 181.527 1.00 153.38 ? 143  ASN A H    1 
ATOM   2043 H HA   . ASN A 1 128 ? 202.626 124.147 179.738 1.00 153.65 ? 143  ASN A HA   1 
ATOM   2044 H HB2  . ASN A 1 128 ? 204.416 123.741 181.411 1.00 154.21 ? 143  ASN A HB2  1 
ATOM   2045 H HB3  . ASN A 1 128 ? 203.520 122.336 182.006 1.00 153.64 ? 143  ASN A HB3  1 
ATOM   2046 H HD21 . ASN A 1 128 ? 204.940 120.690 181.347 1.00 153.99 ? 143  ASN A HD21 1 
ATOM   2047 H HD22 . ASN A 1 128 ? 205.363 120.439 179.657 1.00 154.16 ? 143  ASN A HD22 1 
ATOM   2048 N N    . GLY A 1 129 ? 200.253 122.974 179.605 1.00 147.36 ? 144  GLY A N    1 
ATOM   2049 C CA   . GLY A 1 129 ? 199.167 122.112 179.122 1.00 149.54 ? 144  GLY A CA   1 
ATOM   2050 C C    . GLY A 1 129 ? 197.968 122.015 180.059 1.00 151.58 ? 144  GLY A C    1 
ATOM   2051 O O    . GLY A 1 129 ? 196.898 121.582 179.638 1.00 155.50 ? 144  GLY A O    1 
ATOM   2052 H H    . GLY A 1 129 ? 200.184 123.964 179.419 1.00 149.87 ? 144  GLY A H    1 
ATOM   2053 H HA2  . GLY A 1 129 ? 198.805 122.499 178.169 1.00 150.09 ? 144  GLY A HA2  1 
ATOM   2054 H HA3  . GLY A 1 129 ? 199.540 121.101 178.956 1.00 149.93 ? 144  GLY A HA3  1 
ATOM   2055 N N    . VAL A 1 130 ? 198.105 122.486 181.296 1.00 149.57 ? 145  VAL A N    1 
ATOM   2056 C CA   . VAL A 1 130 ? 196.984 122.729 182.207 1.00 146.58 ? 145  VAL A CA   1 
ATOM   2057 C C    . VAL A 1 130 ? 196.733 124.225 182.272 1.00 145.17 ? 145  VAL A C    1 
ATOM   2058 O O    . VAL A 1 130 ? 197.644 124.980 182.580 1.00 152.11 ? 145  VAL A O    1 
ATOM   2059 C CB   . VAL A 1 130 ? 197.304 122.179 183.604 1.00 145.48 ? 145  VAL A CB   1 
ATOM   2060 C CG1  . VAL A 1 130 ? 196.190 122.501 184.598 1.00 148.46 ? 145  VAL A CG1  1 
ATOM   2061 C CG2  . VAL A 1 130 ? 197.476 120.661 183.567 1.00 149.26 ? 145  VAL A CG2  1 
ATOM   2062 H H    . VAL A 1 130 ? 199.025 122.773 181.599 1.00 149.24 ? 145  VAL A H    1 
ATOM   2063 H HA   . VAL A 1 130 ? 196.081 122.238 181.846 1.00 148.97 ? 145  VAL A HA   1 
ATOM   2064 H HB   . VAL A 1 130 ? 198.230 122.621 183.970 1.00 148.31 ? 145  VAL A HB   1 
ATOM   2065 H HG11 . VAL A 1 130 ? 196.399 122.017 185.552 1.00 149.24 ? 145  VAL A HG11 1 
ATOM   2066 H HG12 . VAL A 1 130 ? 196.133 123.576 184.771 1.00 148.70 ? 145  VAL A HG12 1 
ATOM   2067 H HG13 . VAL A 1 130 ? 195.243 122.139 184.200 1.00 148.90 ? 145  VAL A HG13 1 
ATOM   2068 H HG21 . VAL A 1 130 ? 197.688 120.289 184.570 1.00 149.28 ? 145  VAL A HG21 1 
ATOM   2069 H HG22 . VAL A 1 130 ? 196.567 120.190 183.192 1.00 149.27 ? 145  VAL A HG22 1 
ATOM   2070 H HG23 . VAL A 1 130 ? 198.312 120.394 182.921 1.00 149.10 ? 145  VAL A HG23 1 
ATOM   2071 N N    . LEU A 1 131 ? 195.521 124.674 181.988 1.00 138.92 ? 146  LEU A N    1 
ATOM   2072 C CA   . LEU A 1 131 ? 195.078 126.041 182.218 1.00 140.71 ? 146  LEU A CA   1 
ATOM   2073 C C    . LEU A 1 131 ? 194.370 126.080 183.570 1.00 142.46 ? 146  LEU A C    1 
ATOM   2074 O O    . LEU A 1 131 ? 193.266 125.557 183.702 1.00 147.01 ? 146  LEU A O    1 
ATOM   2075 C CB   . LEU A 1 131 ? 194.159 126.460 181.057 1.00 141.89 ? 146  LEU A CB   1 
ATOM   2076 C CG   . LEU A 1 131 ? 193.769 127.936 181.097 1.00 143.36 ? 146  LEU A CG   1 
ATOM   2077 C CD1  . LEU A 1 131 ? 194.986 128.815 180.820 1.00 143.34 ? 146  LEU A CD1  1 
ATOM   2078 C CD2  . LEU A 1 131 ? 192.721 128.216 180.034 1.00 141.22 ? 146  LEU A CD2  1 
ATOM   2079 H H    . LEU A 1 131 ? 194.813 124.015 181.694 1.00 142.83 ? 146  LEU A H    1 
ATOM   2080 H HA   . LEU A 1 131 ? 195.942 126.706 182.251 1.00 142.40 ? 146  LEU A HA   1 
ATOM   2081 H HB2  . LEU A 1 131 ? 194.660 126.259 180.110 1.00 142.27 ? 146  LEU A HB2  1 
ATOM   2082 H HB3  . LEU A 1 131 ? 193.250 125.859 181.089 1.00 142.40 ? 146  LEU A HB3  1 
ATOM   2083 H HG   . LEU A 1 131 ? 193.353 128.189 182.072 1.00 142.63 ? 146  LEU A HG   1 
ATOM   2084 H HD11 . LEU A 1 131 ? 194.670 129.843 180.641 1.00 143.26 ? 146  LEU A HD11 1 
ATOM   2085 H HD12 . LEU A 1 131 ? 195.661 128.804 181.676 1.00 141.81 ? 146  LEU A HD12 1 
ATOM   2086 H HD13 . LEU A 1 131 ? 195.512 128.456 179.936 1.00 142.64 ? 146  LEU A HD13 1 
ATOM   2087 H HD21 . LEU A 1 131 ? 192.413 129.259 180.106 1.00 142.48 ? 146  LEU A HD21 1 
ATOM   2088 H HD22 . LEU A 1 131 ? 193.127 128.018 179.043 1.00 142.31 ? 146  LEU A HD22 1 
ATOM   2089 H HD23 . LEU A 1 131 ? 191.848 127.583 180.199 1.00 141.93 ? 146  LEU A HD23 1 
ATOM   2090 N N    . GLU A 1 132 ? 195.000 126.648 184.589 1.00 150.29 ? 147  GLU A N    1 
ATOM   2091 C CA   . GLU A 1 132 ? 194.387 126.803 185.905 1.00 148.84 ? 147  GLU A CA   1 
ATOM   2092 C C    . GLU A 1 132 ? 193.583 128.100 185.938 1.00 151.52 ? 147  GLU A C    1 
ATOM   2093 O O    . GLU A 1 132 ? 194.120 129.175 185.675 1.00 156.41 ? 147  GLU A O    1 
ATOM   2094 C CB   . GLU A 1 132 ? 195.465 126.766 186.994 1.00 150.60 ? 147  GLU A CB   1 
ATOM   2095 C CG   . GLU A 1 132 ? 194.874 127.039 188.385 1.00 156.83 ? 147  GLU A CG   1 
ATOM   2096 C CD   . GLU A 1 132 ? 195.872 126.845 189.537 1.00 163.53 ? 147  GLU A CD   1 
ATOM   2097 O OE1  . GLU A 1 132 ? 197.028 126.433 189.308 1.00 164.33 ? 147  GLU A OE1  1 
ATOM   2098 O OE2  . GLU A 1 132 ? 195.490 127.117 190.699 1.00 161.62 ? 147  GLU A OE2  1 
ATOM   2099 H H    . GLU A 1 132 ? 195.873 127.128 184.421 1.00 154.04 ? 147  GLU A H    1 
ATOM   2100 H HA   . GLU A 1 132 ? 193.703 125.976 186.094 1.00 154.07 ? 147  GLU A HA   1 
ATOM   2101 H HB2  . GLU A 1 132 ? 195.926 125.778 186.980 1.00 154.32 ? 147  GLU A HB2  1 
ATOM   2102 H HB3  . GLU A 1 132 ? 196.224 127.519 186.780 1.00 153.63 ? 147  GLU A HB3  1 
ATOM   2103 H HG2  . GLU A 1 132 ? 194.509 128.065 188.411 1.00 154.79 ? 147  GLU A HG2  1 
ATOM   2104 H HG3  . GLU A 1 132 ? 194.020 126.380 188.537 1.00 154.71 ? 147  GLU A HG3  1 
ATOM   2105 N N    . ILE A 1 133 ? 192.299 128.009 186.273 1.00 135.41 ? 148  ILE A N    1 
ATOM   2106 C CA   . ILE A 1 133 ? 191.412 129.161 186.407 1.00 131.16 ? 148  ILE A CA   1 
ATOM   2107 C C    . ILE A 1 133 ? 190.855 129.217 187.818 1.00 133.63 ? 148  ILE A C    1 
ATOM   2108 O O    . ILE A 1 133 ? 190.277 128.244 188.305 1.00 140.74 ? 148  ILE A O    1 
ATOM   2109 C CB   . ILE A 1 133 ? 190.287 129.132 185.364 1.00 130.01 ? 148  ILE A CB   1 
ATOM   2110 C CG1  . ILE A 1 133 ? 190.897 129.068 183.952 1.00 138.26 ? 148  ILE A CG1  1 
ATOM   2111 C CG2  . ILE A 1 133 ? 189.398 130.369 185.564 1.00 130.98 ? 148  ILE A CG2  1 
ATOM   2112 C CD1  . ILE A 1 133 ? 189.902 129.246 182.803 1.00 141.85 ? 148  ILE A CD1  1 
ATOM   2113 H H    . ILE A 1 133 ? 191.908 127.101 186.481 1.00 138.27 ? 148  ILE A H    1 
ATOM   2114 H HA   . ILE A 1 133 ? 191.983 130.074 186.243 1.00 137.19 ? 148  ILE A HA   1 
ATOM   2115 H HB   . ILE A 1 133 ? 189.677 128.243 185.516 1.00 136.74 ? 148  ILE A HB   1 
ATOM   2116 H HG12 . ILE A 1 133 ? 191.675 129.826 183.861 1.00 137.85 ? 148  ILE A HG12 1 
ATOM   2117 H HG13 . ILE A 1 133 ? 191.366 128.093 183.821 1.00 137.99 ? 148  ILE A HG13 1 
ATOM   2118 H HG21 . ILE A 1 133 ? 188.896 130.332 186.530 1.00 136.42 ? 148  ILE A HG21 1 
ATOM   2119 H HG22 . ILE A 1 133 ? 189.995 131.278 185.506 1.00 136.63 ? 148  ILE A HG22 1 
ATOM   2120 H HG23 . ILE A 1 133 ? 188.616 130.401 184.804 1.00 136.96 ? 148  ILE A HG23 1 
ATOM   2121 H HD11 . ILE A 1 133 ? 190.388 128.983 181.864 1.00 138.34 ? 148  ILE A HD11 1 
ATOM   2122 H HD12 . ILE A 1 133 ? 189.583 130.287 182.741 1.00 138.60 ? 148  ILE A HD12 1 
ATOM   2123 H HD13 . ILE A 1 133 ? 189.037 128.599 182.950 1.00 137.45 ? 148  ILE A HD13 1 
ATOM   2124 N N    . THR A 1 134 ? 190.972 130.367 188.469 1.00 143.24 ? 149  THR A N    1 
ATOM   2125 C CA   . THR A 1 134 ? 190.472 130.579 189.829 1.00 143.89 ? 149  THR A CA   1 
ATOM   2126 C C    . THR A 1 134 ? 189.807 131.937 189.967 1.00 145.22 ? 149  THR A C    1 
ATOM   2127 O O    . THR A 1 134 ? 190.053 132.846 189.180 1.00 153.72 ? 149  THR A O    1 
ATOM   2128 C CB   . THR A 1 134 ? 191.584 130.460 190.874 1.00 144.46 ? 149  THR A CB   1 
ATOM   2129 O OG1  . THR A 1 134 ? 192.526 131.477 190.696 1.00 145.02 ? 149  THR A OG1  1 
ATOM   2130 C CG2  . THR A 1 134 ? 192.336 129.138 190.821 1.00 146.37 ? 149  THR A CG2  1 
ATOM   2131 H H    . THR A 1 134 ? 191.457 131.132 188.024 1.00 145.60 ? 149  THR A H    1 
ATOM   2132 H HA   . THR A 1 134 ? 189.720 129.825 190.059 1.00 145.90 ? 149  THR A HA   1 
ATOM   2133 H HB   . THR A 1 134 ? 191.141 130.565 191.865 1.00 145.89 ? 149  THR A HB   1 
ATOM   2134 H HG1  . THR A 1 134 ? 193.068 131.500 191.488 1.00 146.13 ? 149  THR A HG1  1 
ATOM   2135 H HG21 . THR A 1 134 ? 192.995 129.053 191.683 1.00 145.92 ? 149  THR A HG21 1 
ATOM   2136 H HG22 . THR A 1 134 ? 192.931 129.074 189.909 1.00 146.22 ? 149  THR A HG22 1 
ATOM   2137 H HG23 . THR A 1 134 ? 191.619 128.317 190.836 1.00 145.85 ? 149  THR A HG23 1 
ATOM   2138 N N    . ALA A 1 135 ? 188.954 132.083 190.976 1.00 143.08 ? 150  ALA A N    1 
ATOM   2139 C CA   . ALA A 1 135 ? 188.342 133.347 191.354 1.00 143.03 ? 150  ALA A CA   1 
ATOM   2140 C C    . ALA A 1 135 ? 188.304 133.431 192.877 1.00 146.74 ? 150  ALA A C    1 
ATOM   2141 O O    . ALA A 1 135 ? 187.476 132.782 193.514 1.00 151.18 ? 150  ALA A O    1 
ATOM   2142 C CB   . ALA A 1 135 ? 186.952 133.446 190.727 1.00 142.28 ? 150  ALA A CB   1 
ATOM   2143 H H    . ALA A 1 135 ? 188.739 131.274 191.542 1.00 146.33 ? 150  ALA A H    1 
ATOM   2144 H HA   . ALA A 1 135 ? 188.945 134.173 190.978 1.00 145.69 ? 150  ALA A HA   1 
ATOM   2145 H HB1  . ALA A 1 135 ? 187.019 133.288 189.651 1.00 145.76 ? 150  ALA A HB1  1 
ATOM   2146 H HB2  . ALA A 1 135 ? 186.532 134.433 190.920 1.00 145.95 ? 150  ALA A HB2  1 
ATOM   2147 H HB3  . ALA A 1 135 ? 186.293 132.691 191.158 1.00 145.27 ? 150  ALA A HB3  1 
ATOM   2148 N N    . CYS A 1 136 ? 189.225 134.186 193.465 1.00 160.87 ? 151  CYS A N    1 
ATOM   2149 C CA   . CYS A 1 136 ? 189.476 134.177 194.902 1.00 159.98 ? 151  CYS A CA   1 
ATOM   2150 C C    . CYS A 1 136 ? 189.729 135.579 195.433 1.00 160.94 ? 151  CYS A C    1 
ATOM   2151 O O    . CYS A 1 136 ? 190.063 136.497 194.688 1.00 166.86 ? 151  CYS A O    1 
ATOM   2152 C CB   . CYS A 1 136 ? 190.673 133.277 195.219 1.00 164.06 ? 151  CYS A CB   1 
ATOM   2153 S SG   . CYS A 1 136 ? 190.605 131.584 194.590 1.00 189.04 ? 151  CYS A SG   1 
ATOM   2154 H H    . CYS A 1 136 ? 189.841 134.738 192.884 1.00 163.01 ? 151  CYS A H    1 
ATOM   2155 H HA   . CYS A 1 136 ? 188.602 133.786 195.423 1.00 163.42 ? 151  CYS A HA   1 
ATOM   2156 H HB2  . CYS A 1 136 ? 191.566 133.748 194.805 1.00 163.73 ? 151  CYS A HB2  1 
ATOM   2157 H HB3  . CYS A 1 136 ? 190.807 133.229 196.299 1.00 164.32 ? 151  CYS A HB3  1 
ATOM   2158 N N    . GLN A 1 137 ? 189.603 135.751 196.741 1.00 157.84 ? 152  GLN A N    1 
ATOM   2159 C CA   . GLN A 1 137 ? 189.995 136.978 197.424 1.00 159.35 ? 152  GLN A CA   1 
ATOM   2160 C C    . GLN A 1 137 ? 191.516 137.062 197.609 1.00 159.31 ? 152  GLN A C    1 
ATOM   2161 O O    . GLN A 1 137 ? 192.019 137.090 198.727 1.00 160.65 ? 152  GLN A O    1 
ATOM   2162 C CB   . GLN A 1 137 ? 189.239 137.080 198.751 1.00 160.41 ? 152  GLN A CB   1 
ATOM   2163 C CG   . GLN A 1 137 ? 187.721 137.130 198.551 1.00 161.59 ? 152  GLN A CG   1 
ATOM   2164 C CD   . GLN A 1 137 ? 187.017 137.849 199.695 1.00 161.68 ? 152  GLN A CD   1 
ATOM   2165 O OE1  . GLN A 1 137 ? 186.368 138.869 199.516 1.00 161.02 ? 152  GLN A OE1  1 
ATOM   2166 N NE2  . GLN A 1 137 ? 187.136 137.376 200.915 1.00 162.22 ? 152  GLN A NE2  1 
ATOM   2167 H H    . GLN A 1 137 ? 189.281 134.973 197.300 1.00 160.15 ? 152  GLN A H    1 
ATOM   2168 H HA   . GLN A 1 137 ? 189.706 137.830 196.809 1.00 159.85 ? 152  GLN A HA   1 
ATOM   2169 H HB2  . GLN A 1 137 ? 189.495 136.243 199.400 1.00 159.98 ? 152  GLN A HB2  1 
ATOM   2170 H HB3  . GLN A 1 137 ? 189.555 138.006 199.231 1.00 159.88 ? 152  GLN A HB3  1 
ATOM   2171 H HG2  . GLN A 1 137 ? 187.491 137.657 197.625 1.00 159.58 ? 152  GLN A HG2  1 
ATOM   2172 H HG3  . GLN A 1 137 ? 187.341 136.112 198.482 1.00 160.37 ? 152  GLN A HG3  1 
ATOM   2173 H HE21 . GLN A 1 137 ? 187.708 136.565 201.104 1.00 159.98 ? 152  GLN A HE21 1 
ATOM   2174 H HE22 . GLN A 1 137 ? 186.686 137.881 201.665 1.00 160.55 ? 152  GLN A HE22 1 
ATOM   2175 N N    . TYR A 1 138 ? 192.269 137.057 196.513 1.00 149.80 ? 153  TYR A N    1 
ATOM   2176 C CA   . TYR A 1 138 ? 193.725 137.106 196.553 1.00 148.85 ? 153  TYR A CA   1 
ATOM   2177 C C    . TYR A 1 138 ? 194.257 138.409 197.144 1.00 152.47 ? 153  TYR A C    1 
ATOM   2178 O O    . TYR A 1 138 ? 193.818 139.495 196.771 1.00 152.67 ? 153  TYR A O    1 
ATOM   2179 C CB   . TYR A 1 138 ? 194.281 136.920 195.140 1.00 147.35 ? 153  TYR A CB   1 
ATOM   2180 C CG   . TYR A 1 138 ? 194.133 135.518 194.596 1.00 145.78 ? 153  TYR A CG   1 
ATOM   2181 C CD1  . TYR A 1 138 ? 194.775 134.459 195.256 1.00 149.30 ? 153  TYR A CD1  1 
ATOM   2182 C CD2  . TYR A 1 138 ? 193.412 135.274 193.415 1.00 146.51 ? 153  TYR A CD2  1 
ATOM   2183 C CE1  . TYR A 1 138 ? 194.697 133.152 194.750 1.00 154.19 ? 153  TYR A CE1  1 
ATOM   2184 C CE2  . TYR A 1 138 ? 193.337 133.969 192.900 1.00 151.12 ? 153  TYR A CE2  1 
ATOM   2185 C CZ   . TYR A 1 138 ? 193.976 132.906 193.568 1.00 156.20 ? 153  TYR A CZ   1 
ATOM   2186 O OH   . TYR A 1 138 ? 193.906 131.642 193.076 1.00 157.51 ? 153  TYR A OH   1 
ATOM   2187 H H    . TYR A 1 138 ? 191.809 137.018 195.614 1.00 152.07 ? 153  TYR A H    1 
ATOM   2188 H HA   . TYR A 1 138 ? 194.081 136.288 197.179 1.00 151.30 ? 153  TYR A HA   1 
ATOM   2189 H HB2  . TYR A 1 138 ? 193.805 137.633 194.467 1.00 151.21 ? 153  TYR A HB2  1 
ATOM   2190 H HB3  . TYR A 1 138 ? 195.346 137.151 195.154 1.00 151.41 ? 153  TYR A HB3  1 
ATOM   2191 H HD1  . TYR A 1 138 ? 195.344 134.651 196.154 1.00 151.54 ? 153  TYR A HD1  1 
ATOM   2192 H HD2  . TYR A 1 138 ? 192.930 136.086 192.892 1.00 150.93 ? 153  TYR A HD2  1 
ATOM   2193 H HE1  . TYR A 1 138 ? 195.199 132.344 195.263 1.00 151.82 ? 153  TYR A HE1  1 
ATOM   2194 H HE2  . TYR A 1 138 ? 192.791 133.778 191.987 1.00 151.72 ? 153  TYR A HE2  1 
ATOM   2195 H HH   . TYR A 1 138 ? 194.409 131.037 193.626 1.00 152.24 ? 153  TYR A HH   1 
ATOM   2196 N N    . THR A 1 139 ? 195.265 138.324 198.004 1.00 156.85 ? 154  THR A N    1 
ATOM   2197 C CA   . THR A 1 139 ? 196.078 139.475 198.404 1.00 153.93 ? 154  THR A CA   1 
ATOM   2198 C C    . THR A 1 139 ? 197.079 139.777 197.295 1.00 158.74 ? 154  THR A C    1 
ATOM   2199 O O    . THR A 1 139 ? 198.223 139.332 197.352 1.00 165.96 ? 154  THR A O    1 
ATOM   2200 C CB   . THR A 1 139 ? 196.795 139.194 199.729 1.00 158.04 ? 154  THR A CB   1 
ATOM   2201 O OG1  . THR A 1 139 ? 195.859 138.857 200.721 1.00 163.16 ? 154  THR A OG1  1 
ATOM   2202 C CG2  . THR A 1 139 ? 197.564 140.400 200.252 1.00 159.83 ? 154  THR A CG2  1 
ATOM   2203 H H    . THR A 1 139 ? 195.558 137.406 198.311 1.00 159.58 ? 154  THR A H    1 
ATOM   2204 H HA   . THR A 1 139 ? 195.444 140.352 198.539 1.00 158.42 ? 154  THR A HA   1 
ATOM   2205 H HB   . THR A 1 139 ? 197.480 138.356 199.604 1.00 159.83 ? 154  THR A HB   1 
ATOM   2206 H HG1  . THR A 1 139 ? 195.716 137.916 200.599 1.00 160.24 ? 154  THR A HG1  1 
ATOM   2207 H HG21 . THR A 1 139 ? 197.970 140.173 201.237 1.00 159.71 ? 154  THR A HG21 1 
ATOM   2208 H HG22 . THR A 1 139 ? 198.399 140.620 199.586 1.00 159.76 ? 154  THR A HG22 1 
ATOM   2209 H HG23 . THR A 1 139 ? 196.909 141.269 200.318 1.00 159.67 ? 154  THR A HG23 1 
ATOM   2210 N N    . MET A 1 140 ? 196.650 140.470 196.241 1.00 150.04 ? 155  MET A N    1 
ATOM   2211 C CA   . MET A 1 140 ? 197.512 140.759 195.093 1.00 147.09 ? 155  MET A CA   1 
ATOM   2212 C C    . MET A 1 140 ? 198.705 141.635 195.489 1.00 149.53 ? 155  MET A C    1 
ATOM   2213 O O    . MET A 1 140 ? 198.560 142.592 196.252 1.00 154.28 ? 155  MET A O    1 
ATOM   2214 C CB   . MET A 1 140 ? 196.724 141.443 193.973 1.00 151.31 ? 155  MET A CB   1 
ATOM   2215 C CG   . MET A 1 140 ? 195.611 140.572 193.385 1.00 157.15 ? 155  MET A CG   1 
ATOM   2216 S SD   . MET A 1 140 ? 196.181 139.049 192.609 1.00 165.65 ? 155  MET A SD   1 
ATOM   2217 C CE   . MET A 1 140 ? 197.135 139.706 191.221 1.00 155.80 ? 155  MET A CE   1 
ATOM   2218 H H    . MET A 1 140 ? 195.686 140.772 196.213 1.00 153.69 ? 155  MET A H    1 
ATOM   2219 H HA   . MET A 1 140 ? 197.900 139.815 194.709 1.00 153.23 ? 155  MET A HA   1 
ATOM   2220 H HB2  . MET A 1 140 ? 196.285 142.362 194.362 1.00 153.92 ? 155  MET A HB2  1 
ATOM   2221 H HB3  . MET A 1 140 ? 197.411 141.724 193.175 1.00 153.46 ? 155  MET A HB3  1 
ATOM   2222 H HG2  . MET A 1 140 ? 194.905 140.315 194.174 1.00 154.36 ? 155  MET A HG2  1 
ATOM   2223 H HG3  . MET A 1 140 ? 195.073 141.150 192.632 1.00 154.18 ? 155  MET A HG3  1 
ATOM   2224 H HE1  . MET A 1 140 ? 197.487 138.879 190.604 1.00 153.85 ? 155  MET A HE1  1 
ATOM   2225 H HE2  . MET A 1 140 ? 197.999 140.258 191.590 1.00 153.70 ? 155  MET A HE2  1 
ATOM   2226 H HE3  . MET A 1 140 ? 196.506 140.363 190.620 1.00 153.99 ? 155  MET A HE3  1 
ATOM   2227 N N    . CYS A 1 141 ? 199.881 141.334 194.946 1.00 160.75 ? 156  CYS A N    1 
ATOM   2228 C CA   . CYS A 1 141 ? 201.070 142.160 195.139 1.00 165.21 ? 156  CYS A CA   1 
ATOM   2229 C C    . CYS A 1 141 ? 200.927 143.543 194.491 1.00 162.51 ? 156  CYS A C    1 
ATOM   2230 O O    . CYS A 1 141 ? 200.162 143.700 193.548 1.00 163.19 ? 156  CYS A O    1 
ATOM   2231 C CB   . CYS A 1 141 ? 202.280 141.454 194.530 1.00 168.01 ? 156  CYS A CB   1 
ATOM   2232 S SG   . CYS A 1 141 ? 202.652 139.843 195.244 1.00 186.08 ? 156  CYS A SG   1 
ATOM   2233 H H    . CYS A 1 141 ? 199.936 140.539 194.326 1.00 165.45 ? 156  CYS A H    1 
ATOM   2234 H HA   . CYS A 1 141 ? 201.239 142.291 196.208 1.00 166.37 ? 156  CYS A HA   1 
ATOM   2235 H HB2  . CYS A 1 141 ? 202.105 141.324 193.463 1.00 166.20 ? 156  CYS A HB2  1 
ATOM   2236 H HB3  . CYS A 1 141 ? 203.161 142.084 194.654 1.00 166.32 ? 156  CYS A HB3  1 
ATOM   2237 N N    . GLU A 1 142 ? 201.734 144.519 194.910 1.00 161.33 ? 157  GLU A N    1 
ATOM   2238 C CA   . GLU A 1 142 ? 201.864 145.806 194.204 1.00 159.92 ? 157  GLU A CA   1 
ATOM   2239 C C    . GLU A 1 142 ? 202.376 145.651 192.767 1.00 163.47 ? 157  GLU A C    1 
ATOM   2240 O O    . GLU A 1 142 ? 201.924 146.340 191.851 1.00 169.24 ? 157  GLU A O    1 
ATOM   2241 C CB   . GLU A 1 142 ? 202.839 146.713 194.953 1.00 162.22 ? 157  GLU A CB   1 
ATOM   2242 C CG   . GLU A 1 142 ? 202.231 147.254 196.247 1.00 167.30 ? 157  GLU A CG   1 
ATOM   2243 C CD   . GLU A 1 142 ? 203.233 148.107 197.035 1.00 172.67 ? 157  GLU A CD   1 
ATOM   2244 O OE1  . GLU A 1 142 ? 204.362 147.641 197.304 1.00 170.04 ? 157  GLU A OE1  1 
ATOM   2245 O OE2  . GLU A 1 142 ? 202.886 149.255 197.391 1.00 174.16 ? 157  GLU A OE2  1 
ATOM   2246 H H    . GLU A 1 142 ? 202.259 144.380 195.761 1.00 164.85 ? 157  GLU A H    1 
ATOM   2247 H HA   . GLU A 1 142 ? 200.898 146.312 194.181 1.00 163.65 ? 157  GLU A HA   1 
ATOM   2248 H HB2  . GLU A 1 142 ? 203.752 146.157 195.169 1.00 164.23 ? 157  GLU A HB2  1 
ATOM   2249 H HB3  . GLU A 1 142 ? 203.096 147.563 194.321 1.00 164.44 ? 157  GLU A HB3  1 
ATOM   2250 H HG2  . GLU A 1 142 ? 201.353 147.846 195.991 1.00 164.63 ? 157  GLU A HG2  1 
ATOM   2251 H HG3  . GLU A 1 142 ? 201.905 146.420 196.868 1.00 164.57 ? 157  GLU A HG3  1 
ATOM   2252 N N    . TYR A 1 143 ? 203.312 144.720 192.585 1.00 145.34 ? 158  TYR A N    1 
ATOM   2253 C CA   . TYR A 1 143 ? 204.047 144.488 191.351 1.00 146.83 ? 158  TYR A CA   1 
ATOM   2254 C C    . TYR A 1 143 ? 204.023 142.991 191.005 1.00 146.35 ? 158  TYR A C    1 
ATOM   2255 O O    . TYR A 1 143 ? 205.026 142.298 191.165 1.00 143.24 ? 158  TYR A O    1 
ATOM   2256 C CB   . TYR A 1 143 ? 205.472 145.035 191.528 1.00 141.90 ? 158  TYR A CB   1 
ATOM   2257 C CG   . TYR A 1 143 ? 205.570 146.463 192.029 1.00 140.63 ? 158  TYR A CG   1 
ATOM   2258 C CD1  . TYR A 1 143 ? 204.961 147.508 191.323 1.00 143.51 ? 158  TYR A CD1  1 
ATOM   2259 C CD2  . TYR A 1 143 ? 206.287 146.745 193.200 1.00 142.05 ? 158  TYR A CD2  1 
ATOM   2260 C CE1  . TYR A 1 143 ? 205.089 148.837 191.759 1.00 141.41 ? 158  TYR A CE1  1 
ATOM   2261 C CE2  . TYR A 1 143 ? 206.401 148.068 193.654 1.00 142.91 ? 158  TYR A CE2  1 
ATOM   2262 C CZ   . TYR A 1 143 ? 205.805 149.116 192.934 1.00 142.89 ? 158  TYR A CZ   1 
ATOM   2263 O OH   . TYR A 1 143 ? 205.924 150.390 193.375 1.00 151.94 ? 158  TYR A OH   1 
ATOM   2264 H H    . TYR A 1 143 ? 203.622 144.222 193.407 1.00 146.01 ? 158  TYR A H    1 
ATOM   2265 H HA   . TYR A 1 143 ? 203.580 145.030 190.530 1.00 146.39 ? 158  TYR A HA   1 
ATOM   2266 H HB2  . TYR A 1 143 ? 206.008 144.395 192.227 1.00 145.20 ? 158  TYR A HB2  1 
ATOM   2267 H HB3  . TYR A 1 143 ? 205.990 144.973 190.572 1.00 145.30 ? 158  TYR A HB3  1 
ATOM   2268 H HD1  . TYR A 1 143 ? 204.381 147.287 190.443 1.00 146.68 ? 158  TYR A HD1  1 
ATOM   2269 H HD2  . TYR A 1 143 ? 206.751 145.945 193.755 1.00 146.20 ? 158  TYR A HD2  1 
ATOM   2270 H HE1  . TYR A 1 143 ? 204.632 149.638 191.201 1.00 145.90 ? 158  TYR A HE1  1 
ATOM   2271 H HE2  . TYR A 1 143 ? 206.945 148.287 194.557 1.00 146.15 ? 158  TYR A HE2  1 
ATOM   2272 H HH   . TYR A 1 143 ? 205.426 151.007 192.842 1.00 146.29 ? 158  TYR A HH   1 
ATOM   2273 N N    . PRO A 1 144 ? 202.869 142.432 190.614 1.00 145.14 ? 159  PRO A N    1 
ATOM   2274 C CA   . PRO A 1 144 ? 202.721 141.001 190.399 1.00 143.22 ? 159  PRO A CA   1 
ATOM   2275 C C    . PRO A 1 144 ? 203.458 140.541 189.143 1.00 144.77 ? 159  PRO A C    1 
ATOM   2276 O O    . PRO A 1 144 ? 203.483 141.250 188.143 1.00 150.01 ? 159  PRO A O    1 
ATOM   2277 C CB   . PRO A 1 144 ? 201.216 140.772 190.275 1.00 140.34 ? 159  PRO A CB   1 
ATOM   2278 C CG   . PRO A 1 144 ? 200.696 142.097 189.737 1.00 139.79 ? 159  PRO A CG   1 
ATOM   2279 C CD   . PRO A 1 144 ? 201.609 143.115 190.408 1.00 142.67 ? 159  PRO A CD   1 
ATOM   2280 H HA   . PRO A 1 144 ? 203.110 140.456 191.259 1.00 145.40 ? 159  PRO A HA   1 
ATOM   2281 H HB2  . PRO A 1 144 ? 200.974 139.945 189.606 1.00 144.56 ? 159  PRO A HB2  1 
ATOM   2282 H HB3  . PRO A 1 144 ? 200.787 140.603 191.263 1.00 145.60 ? 159  PRO A HB3  1 
ATOM   2283 H HG2  . PRO A 1 144 ? 200.835 142.142 188.657 1.00 145.34 ? 159  PRO A HG2  1 
ATOM   2284 H HG3  . PRO A 1 144 ? 199.649 142.253 189.998 1.00 144.78 ? 159  PRO A HG3  1 
ATOM   2285 H HD2  . PRO A 1 144 ? 201.722 143.999 189.782 1.00 145.04 ? 159  PRO A HD2  1 
ATOM   2286 H HD3  . PRO A 1 144 ? 201.190 143.397 191.374 1.00 146.18 ? 159  PRO A HD3  1 
ATOM   2287 N N    . HIS A 1 145 ? 204.022 139.338 189.137 1.00 143.16 ? 160  HIS A N    1 
ATOM   2288 C CA   . HIS A 1 145 ? 204.585 138.745 187.923 1.00 144.01 ? 160  HIS A CA   1 
ATOM   2289 C C    . HIS A 1 145 ? 204.683 137.221 188.041 1.00 148.52 ? 160  HIS A C    1 
ATOM   2290 O O    . HIS A 1 145 ? 204.654 136.676 189.143 1.00 155.36 ? 160  HIS A O    1 
ATOM   2291 C CB   . HIS A 1 145 ? 205.962 139.358 187.652 1.00 141.83 ? 160  HIS A CB   1 
ATOM   2292 C CG   . HIS A 1 145 ? 207.004 138.827 188.574 1.00 139.78 ? 160  HIS A CG   1 
ATOM   2293 N ND1  . HIS A 1 145 ? 207.648 137.624 188.433 1.00 147.83 ? 160  HIS A ND1  1 
ATOM   2294 C CD2  . HIS A 1 145 ? 207.350 139.347 189.785 1.00 139.17 ? 160  HIS A CD2  1 
ATOM   2295 C CE1  . HIS A 1 145 ? 208.382 137.428 189.532 1.00 147.20 ? 160  HIS A CE1  1 
ATOM   2296 N NE2  . HIS A 1 145 ? 208.242 138.457 190.383 1.00 143.18 ? 160  HIS A NE2  1 
ATOM   2297 H H    . HIS A 1 145 ? 204.051 138.793 189.987 1.00 146.63 ? 160  HIS A H    1 
ATOM   2298 H HA   . HIS A 1 145 ? 203.936 138.976 187.078 1.00 146.80 ? 160  HIS A HA   1 
ATOM   2299 H HB2  . HIS A 1 145 ? 206.275 139.121 186.636 1.00 146.85 ? 160  HIS A HB2  1 
ATOM   2300 H HB3  . HIS A 1 145 ? 205.924 140.444 187.735 1.00 146.46 ? 160  HIS A HB3  1 
ATOM   2301 H HD1  . HIS A 1 145 ? 207.505 136.962 187.683 1.00 147.45 ? 160  HIS A HD1  1 
ATOM   2302 H HD2  . HIS A 1 145 ? 206.959 140.256 190.220 1.00 146.13 ? 160  HIS A HD2  1 
ATOM   2303 H HE1  . HIS A 1 145 ? 209.005 136.562 189.705 1.00 146.72 ? 160  HIS A HE1  1 
ATOM   2304 N N    . THR A 1 146 ? 204.857 136.525 186.920 1.00 145.20 ? 161  THR A N    1 
ATOM   2305 C CA   . THR A 1 146 ? 205.090 135.070 186.885 1.00 143.97 ? 161  THR A CA   1 
ATOM   2306 C C    . THR A 1 146 ? 206.521 134.744 186.448 1.00 145.08 ? 161  THR A C    1 
ATOM   2307 O O    . THR A 1 146 ? 207.326 135.656 186.206 1.00 151.76 ? 161  THR A O    1 
ATOM   2308 C CB   . THR A 1 146 ? 204.051 134.371 186.001 1.00 145.61 ? 161  THR A CB   1 
ATOM   2309 O OG1  . THR A 1 146 ? 204.153 134.808 184.670 1.00 154.59 ? 161  THR A OG1  1 
ATOM   2310 C CG2  . THR A 1 146 ? 202.634 134.666 186.467 1.00 145.76 ? 161  THR A CG2  1 
ATOM   2311 H H    . THR A 1 146 ? 204.871 137.021 186.040 1.00 147.87 ? 161  THR A H    1 
ATOM   2312 H HA   . THR A 1 146 ? 204.969 134.660 187.887 1.00 148.18 ? 161  THR A HA   1 
ATOM   2313 H HB   . THR A 1 146 ? 204.213 133.293 186.025 1.00 147.96 ? 161  THR A HB   1 
ATOM   2314 H HG1  . THR A 1 146 ? 203.581 134.244 184.145 1.00 149.10 ? 161  THR A HG1  1 
ATOM   2315 H HG21 . THR A 1 146 ? 201.934 134.057 185.894 1.00 148.32 ? 161  THR A HG21 1 
ATOM   2316 H HG22 . THR A 1 146 ? 202.399 135.721 186.322 1.00 147.71 ? 161  THR A HG22 1 
ATOM   2317 H HG23 . THR A 1 146 ? 202.534 134.412 187.522 1.00 147.53 ? 161  THR A HG23 1 
ATOM   2318 N N    . ILE A 1 147 ? 206.882 133.460 186.378 1.00 153.38 ? 162  ILE A N    1 
ATOM   2319 C CA   . ILE A 1 147 ? 208.205 133.002 185.922 1.00 156.76 ? 162  ILE A CA   1 
ATOM   2320 C C    . ILE A 1 147 ? 208.123 131.873 184.895 1.00 159.36 ? 162  ILE A C    1 
ATOM   2321 O O    . ILE A 1 147 ? 207.196 131.070 184.916 1.00 158.69 ? 162  ILE A O    1 
ATOM   2322 C CB   . ILE A 1 147 ? 209.123 132.597 187.098 1.00 158.38 ? 162  ILE A CB   1 
ATOM   2323 C CG1  . ILE A 1 147 ? 208.750 131.241 187.733 1.00 160.08 ? 162  ILE A CG1  1 
ATOM   2324 C CG2  . ILE A 1 147 ? 209.196 133.727 188.133 1.00 160.98 ? 162  ILE A CG2  1 
ATOM   2325 C CD1  . ILE A 1 147 ? 209.656 130.824 188.898 1.00 161.03 ? 162  ILE A CD1  1 
ATOM   2326 H H    . ILE A 1 147 ? 206.218 132.765 186.687 1.00 160.50 ? 162  ILE A H    1 
ATOM   2327 H HA   . ILE A 1 147 ? 208.689 133.838 185.417 1.00 161.39 ? 162  ILE A HA   1 
ATOM   2328 H HB   . ILE A 1 147 ? 210.127 132.481 186.688 1.00 161.10 ? 162  ILE A HB   1 
ATOM   2329 H HG12 . ILE A 1 147 ? 207.718 131.273 188.081 1.00 161.24 ? 162  ILE A HG12 1 
ATOM   2330 H HG13 . ILE A 1 147 ? 208.830 130.457 186.979 1.00 161.53 ? 162  ILE A HG13 1 
ATOM   2331 H HG21 . ILE A 1 147 ? 209.982 133.521 188.860 1.00 161.44 ? 162  ILE A HG21 1 
ATOM   2332 H HG22 . ILE A 1 147 ? 208.241 133.823 188.650 1.00 161.38 ? 162  ILE A HG22 1 
ATOM   2333 H HG23 . ILE A 1 147 ? 209.437 134.666 187.635 1.00 161.42 ? 162  ILE A HG23 1 
ATOM   2334 H HD11 . ILE A 1 147 ? 209.415 129.805 189.198 1.00 161.50 ? 162  ILE A HD11 1 
ATOM   2335 H HD12 . ILE A 1 147 ? 210.701 130.861 188.587 1.00 161.53 ? 162  ILE A HD12 1 
ATOM   2336 H HD13 . ILE A 1 147 ? 209.506 131.480 189.756 1.00 161.15 ? 162  ILE A HD13 1 
ATOM   2337 N N    . CYS A 1 148 ? 209.148 131.744 184.053 1.00 186.26 ? 163  CYS A N    1 
ATOM   2338 C CA   . CYS A 1 148 ? 209.402 130.507 183.313 1.00 186.82 ? 163  CYS A CA   1 
ATOM   2339 C C    . CYS A 1 148 ? 209.746 129.366 184.274 1.00 188.88 ? 163  CYS A C    1 
ATOM   2340 O O    . CYS A 1 148 ? 210.884 129.255 184.728 1.00 189.61 ? 163  CYS A O    1 
ATOM   2341 C CB   . CYS A 1 148 ? 210.592 130.701 182.380 1.00 191.44 ? 163  CYS A CB   1 
ATOM   2342 S SG   . CYS A 1 148 ? 210.254 131.567 180.851 1.00 208.56 ? 163  CYS A SG   1 
ATOM   2343 H H    . CYS A 1 148 ? 209.846 132.474 184.024 1.00 188.18 ? 163  CYS A H    1 
ATOM   2344 H HA   . CYS A 1 148 ? 208.529 130.231 182.723 1.00 187.55 ? 163  CYS A HA   1 
ATOM   2345 H HB2  . CYS A 1 148 ? 211.383 131.226 182.915 1.00 189.41 ? 163  CYS A HB2  1 
ATOM   2346 H HB3  . CYS A 1 148 ? 210.985 129.724 182.099 1.00 188.76 ? 163  CYS A HB3  1 
ATOM   2347 N N    . LYS A 1 149 ? 208.802 128.474 184.562 1.00 185.35 ? 164  LYS A N    1 
ATOM   2348 C CA   . LYS A 1 149 ? 209.069 127.285 185.386 1.00 186.41 ? 164  LYS A CA   1 
ATOM   2349 C C    . LYS A 1 149 ? 209.953 126.264 184.662 1.00 184.53 ? 164  LYS A C    1 
ATOM   2350 O O    . LYS A 1 149 ? 210.721 125.551 185.301 1.00 181.86 ? 164  LYS A O    1 
ATOM   2351 C CB   . LYS A 1 149 ? 207.726 126.680 185.800 1.00 185.32 ? 164  LYS A CB   1 
ATOM   2352 C CG   . LYS A 1 149 ? 206.978 127.572 186.805 1.00 186.71 ? 164  LYS A CG   1 
ATOM   2353 C CD   . LYS A 1 149 ? 207.456 127.356 188.247 1.00 187.03 ? 164  LYS A CD   1 
ATOM   2354 C CE   . LYS A 1 149 ? 206.555 128.136 189.212 1.00 188.10 ? 164  LYS A CE   1 
ATOM   2355 N NZ   . LYS A 1 149 ? 206.871 127.828 190.631 1.00 187.85 ? 164  LYS A NZ   1 
ATOM   2356 H H    . LYS A 1 149 ? 207.867 128.631 184.213 1.00 184.03 ? 164  LYS A H    1 
ATOM   2357 H HA   . LYS A 1 149 ? 209.617 127.575 186.283 1.00 184.77 ? 164  LYS A HA   1 
ATOM   2358 H HB2  . LYS A 1 149 ? 207.104 126.547 184.914 1.00 184.00 ? 164  LYS A HB2  1 
ATOM   2359 H HB3  . LYS A 1 149 ? 207.882 125.697 186.242 1.00 184.36 ? 164  LYS A HB3  1 
ATOM   2360 H HG2  . LYS A 1 149 ? 207.068 128.625 186.536 1.00 184.43 ? 164  LYS A HG2  1 
ATOM   2361 H HG3  . LYS A 1 149 ? 205.923 127.305 186.759 1.00 184.35 ? 164  LYS A HG3  1 
ATOM   2362 H HD2  . LYS A 1 149 ? 207.396 126.293 188.483 1.00 184.37 ? 164  LYS A HD2  1 
ATOM   2363 H HD3  . LYS A 1 149 ? 208.490 127.685 188.348 1.00 184.76 ? 164  LYS A HD3  1 
ATOM   2364 H HE2  . LYS A 1 149 ? 206.668 129.203 189.019 1.00 184.70 ? 164  LYS A HE2  1 
ATOM   2365 H HE3  . LYS A 1 149 ? 205.518 127.873 189.005 1.00 184.62 ? 164  LYS A HE3  1 
ATOM   2366 H HZ1  . LYS A 1 149 ? 206.739 126.846 190.824 1.00 184.62 ? 164  LYS A HZ1  1 
ATOM   2367 H HZ2  . LYS A 1 149 ? 206.267 128.343 191.256 1.00 184.71 ? 164  LYS A HZ2  1 
ATOM   2368 H HZ3  . LYS A 1 149 ? 207.828 128.060 190.858 1.00 184.48 ? 164  LYS A HZ3  1 
ATOM   2369 N N    . SER A 1 150 ? 209.883 126.235 183.332 1.00 182.65 ? 165  SER A N    1 
ATOM   2370 C CA   . SER A 1 150 ? 210.728 125.425 182.444 1.00 181.90 ? 165  SER A CA   1 
ATOM   2371 C C    . SER A 1 150 ? 212.197 125.882 182.472 1.00 180.07 ? 165  SER A C    1 
ATOM   2372 O O    . SER A 1 150 ? 213.058 125.168 182.986 1.00 178.78 ? 165  SER A O    1 
ATOM   2373 C CB   . SER A 1 150 ? 210.140 125.458 181.023 1.00 183.39 ? 165  SER A CB   1 
ATOM   2374 O OG   . SER A 1 150 ? 209.905 126.794 180.642 1.00 185.59 ? 165  SER A OG   1 
ATOM   2375 H H    . SER A 1 150 ? 209.191 126.829 182.896 1.00 180.43 ? 165  SER A H    1 
ATOM   2376 H HA   . SER A 1 150 ? 210.705 124.389 182.782 1.00 179.92 ? 165  SER A HA   1 
ATOM   2377 H HB2  . SER A 1 150 ? 210.828 124.981 180.326 1.00 179.98 ? 165  SER A HB2  1 
ATOM   2378 H HB3  . SER A 1 150 ? 209.193 124.918 181.016 1.00 180.13 ? 165  SER A HB3  1 
ATOM   2379 H HG   . SER A 1 150 ? 208.977 127.002 180.767 1.00 180.65 ? 165  SER A HG   1 
ATOM   2380 N N    . LYS A 1 151 ? 212.496 127.075 181.947 1.00 178.96 ? 166  LYS A N    1 
ATOM   2381 C CA   . LYS A 1 151 ? 213.867 127.615 181.805 1.00 179.33 ? 166  LYS A CA   1 
ATOM   2382 C C    . LYS A 1 151 ? 214.434 128.317 183.050 1.00 177.88 ? 166  LYS A C    1 
ATOM   2383 O O    . LYS A 1 151 ? 215.644 128.531 183.117 1.00 174.48 ? 166  LYS A O    1 
ATOM   2384 C CB   . LYS A 1 151 ? 213.898 128.563 180.595 1.00 178.08 ? 166  LYS A CB   1 
ATOM   2385 C CG   . LYS A 1 151 ? 213.892 127.818 179.250 1.00 178.62 ? 166  LYS A CG   1 
ATOM   2386 C CD   . LYS A 1 151 ? 215.276 127.256 178.900 1.00 178.48 ? 166  LYS A CD   1 
ATOM   2387 C CE   . LYS A 1 151 ? 215.268 126.719 177.467 1.00 177.85 ? 166  LYS A CE   1 
ATOM   2388 N NZ   . LYS A 1 151 ? 216.626 126.306 177.030 1.00 178.28 ? 166  LYS A NZ   1 
ATOM   2389 H H    . LYS A 1 151 ? 211.741 127.541 181.465 1.00 177.71 ? 166  LYS A H    1 
ATOM   2390 H HA   . LYS A 1 151 ? 214.551 126.788 181.616 1.00 177.73 ? 166  LYS A HA   1 
ATOM   2391 H HB2  . LYS A 1 151 ? 213.034 129.227 180.636 1.00 177.69 ? 166  LYS A HB2  1 
ATOM   2392 H HB3  . LYS A 1 151 ? 214.788 129.191 180.640 1.00 177.24 ? 166  LYS A HB3  1 
ATOM   2393 H HG2  . LYS A 1 151 ? 213.157 127.013 179.268 1.00 177.32 ? 166  LYS A HG2  1 
ATOM   2394 H HG3  . LYS A 1 151 ? 213.601 128.522 178.470 1.00 177.40 ? 166  LYS A HG3  1 
ATOM   2395 H HD2  . LYS A 1 151 ? 216.017 128.051 178.980 1.00 177.49 ? 166  LYS A HD2  1 
ATOM   2396 H HD3  . LYS A 1 151 ? 215.539 126.458 179.594 1.00 177.40 ? 166  LYS A HD3  1 
ATOM   2397 H HE2  . LYS A 1 151 ? 214.578 125.877 177.410 1.00 177.15 ? 166  LYS A HE2  1 
ATOM   2398 H HE3  . LYS A 1 151 ? 214.893 127.499 176.804 1.00 177.39 ? 166  LYS A HE3  1 
ATOM   2399 H HZ1  . LYS A 1 151 ? 217.032 125.631 177.661 1.00 177.16 ? 166  LYS A HZ1  1 
ATOM   2400 H HZ2  . LYS A 1 151 ? 217.251 127.098 176.987 1.00 177.76 ? 166  LYS A HZ2  1 
ATOM   2401 H HZ3  . LYS A 1 151 ? 216.594 125.893 176.108 1.00 177.60 ? 166  LYS A HZ3  1 
ATOM   2402 N N    . GLY A 1 152 ? 213.607 128.674 184.028 1.00 183.06 ? 167  GLY A N    1 
ATOM   2403 C CA   . GLY A 1 152 ? 214.017 129.410 185.230 1.00 181.44 ? 167  GLY A CA   1 
ATOM   2404 C C    . GLY A 1 152 ? 214.110 130.931 185.048 1.00 183.90 ? 167  GLY A C    1 
ATOM   2405 O O    . GLY A 1 152 ? 214.052 131.462 183.935 1.00 185.81 ? 167  GLY A O    1 
ATOM   2406 H H    . GLY A 1 152 ? 212.622 128.480 183.921 1.00 182.84 ? 167  GLY A H    1 
ATOM   2407 H HA2  . GLY A 1 152 ? 213.297 129.209 186.024 1.00 182.48 ? 167  GLY A HA2  1 
ATOM   2408 H HA3  . GLY A 1 152 ? 214.987 129.050 185.574 1.00 182.47 ? 167  GLY A HA3  1 
ATOM   2409 N N    . SER A 1 153 ? 214.234 131.651 186.166 1.00 178.72 ? 168  SER A N    1 
ATOM   2410 C CA   . SER A 1 153 ? 214.250 133.119 186.226 1.00 180.08 ? 168  SER A CA   1 
ATOM   2411 C C    . SER A 1 153 ? 215.168 133.634 187.335 1.00 178.06 ? 168  SER A C    1 
ATOM   2412 O O    . SER A 1 153 ? 215.405 132.943 188.325 1.00 175.32 ? 168  SER A O    1 
ATOM   2413 C CB   . SER A 1 153 ? 212.826 133.642 186.429 1.00 177.56 ? 168  SER A CB   1 
ATOM   2414 O OG   . SER A 1 153 ? 212.834 135.058 186.391 1.00 179.32 ? 168  SER A OG   1 
ATOM   2415 H H    . SER A 1 153 ? 214.317 131.154 187.041 1.00 177.23 ? 168  SER A H    1 
ATOM   2416 H HA   . SER A 1 153 ? 214.618 133.512 185.279 1.00 178.02 ? 168  SER A HA   1 
ATOM   2417 H HB2  . SER A 1 153 ? 212.190 133.260 185.631 1.00 177.39 ? 168  SER A HB2  1 
ATOM   2418 H HB3  . SER A 1 153 ? 212.442 133.297 187.388 1.00 176.85 ? 168  SER A HB3  1 
ATOM   2419 H HG   . SER A 1 153 ? 211.933 135.383 186.454 1.00 177.90 ? 168  SER A HG   1 
ATOM   2420 N N    . SER A 1 154 ? 215.693 134.853 187.216 1.00 180.10 ? 169  SER A N    1 
ATOM   2421 C CA   . SER A 1 154 ? 216.568 135.444 188.245 1.00 178.99 ? 169  SER A CA   1 
ATOM   2422 C C    . SER A 1 154 ? 215.850 135.856 189.539 1.00 177.64 ? 169  SER A C    1 
ATOM   2423 O O    . SER A 1 154 ? 216.507 136.246 190.503 1.00 174.63 ? 169  SER A O    1 
ATOM   2424 C CB   . SER A 1 154 ? 217.341 136.628 187.675 1.00 180.64 ? 169  SER A CB   1 
ATOM   2425 O OG   . SER A 1 154 ? 216.496 137.742 187.468 1.00 184.44 ? 169  SER A OG   1 
ATOM   2426 H H    . SER A 1 154 ? 215.486 135.382 186.382 1.00 178.82 ? 169  SER A H    1 
ATOM   2427 H HA   . SER A 1 154 ? 217.308 134.695 188.527 1.00 178.46 ? 169  SER A HA   1 
ATOM   2428 H HB2  . SER A 1 154 ? 218.122 136.909 188.380 1.00 178.52 ? 169  SER A HB2  1 
ATOM   2429 H HB3  . SER A 1 154 ? 217.815 136.343 186.736 1.00 178.93 ? 169  SER A HB3  1 
ATOM   2430 H HG   . SER A 1 154 ? 216.002 137.633 186.653 1.00 179.20 ? 169  SER A HG   1 
ATOM   2431 N N    . ARG A 1 155 ? 214.514 135.764 189.586 1.00 175.91 ? 170  ARG A N    1 
ATOM   2432 C CA   . ARG A 1 155 ? 213.672 136.084 190.751 1.00 177.91 ? 170  ARG A CA   1 
ATOM   2433 C C    . ARG A 1 155 ? 212.573 135.039 190.971 1.00 178.37 ? 170  ARG A C    1 
ATOM   2434 O O    . ARG A 1 155 ? 212.169 134.364 190.028 1.00 175.63 ? 170  ARG A O    1 
ATOM   2435 C CB   . ARG A 1 155 ? 213.094 137.503 190.614 1.00 175.04 ? 170  ARG A CB   1 
ATOM   2436 C CG   . ARG A 1 155 ? 212.289 137.726 189.322 1.00 173.05 ? 170  ARG A CG   1 
ATOM   2437 C CD   . ARG A 1 155 ? 211.364 138.939 189.439 1.00 174.48 ? 170  ARG A CD   1 
ATOM   2438 N NE   . ARG A 1 155 ? 212.096 140.213 189.530 1.00 176.50 ? 170  ARG A NE   1 
ATOM   2439 C CZ   . ARG A 1 155 ? 211.997 141.115 190.484 1.00 174.90 ? 170  ARG A CZ   1 
ATOM   2440 N NH1  . ARG A 1 155 ? 212.710 142.190 190.401 1.00 174.35 ? 170  ARG A NH1  1 
ATOM   2441 N NH2  . ARG A 1 155 ? 211.218 140.987 191.513 1.00 172.59 ? 170  ARG A NH2  1 
ATOM   2442 H H    . ARG A 1 155 ? 214.054 135.399 188.765 1.00 174.50 ? 170  ARG A H    1 
ATOM   2443 H HA   . ARG A 1 155 ? 214.293 136.065 191.646 1.00 174.72 ? 170  ARG A HA   1 
ATOM   2444 H HB2  . ARG A 1 155 ? 212.457 137.694 191.477 1.00 174.43 ? 170  ARG A HB2  1 
ATOM   2445 H HB3  . ARG A 1 155 ? 213.907 138.227 190.640 1.00 174.19 ? 170  ARG A HB3  1 
ATOM   2446 H HG2  . ARG A 1 155 ? 212.966 137.857 188.479 1.00 174.08 ? 170  ARG A HG2  1 
ATOM   2447 H HG3  . ARG A 1 155 ? 211.667 136.854 189.129 1.00 173.88 ? 170  ARG A HG3  1 
ATOM   2448 H HD2  . ARG A 1 155 ? 210.713 138.966 188.567 1.00 173.82 ? 170  ARG A HD2  1 
ATOM   2449 H HD3  . ARG A 1 155 ? 210.740 138.794 190.320 1.00 173.83 ? 170  ARG A HD3  1 
ATOM   2450 H HE   . ARG A 1 155 ? 212.731 140.444 188.780 1.00 174.39 ? 170  ARG A HE   1 
ATOM   2451 H HH11 . ARG A 1 155 ? 213.287 142.334 189.586 1.00 174.39 ? 170  ARG A HH11 1 
ATOM   2452 H HH12 . ARG A 1 155 ? 212.714 142.861 191.154 1.00 173.87 ? 170  ARG A HH12 1 
ATOM   2453 H HH21 . ARG A 1 155 ? 210.602 140.190 191.572 1.00 173.86 ? 170  ARG A HH21 1 
ATOM   2454 H HH22 . ARG A 1 155 ? 211.170 141.723 192.201 1.00 173.63 ? 170  ARG A HH22 1 
ATOM   2455 N N    . ASN A 1 156 ? 212.087 134.910 192.206 1.00 178.06 ? 171  ASN A N    1 
ATOM   2456 C CA   . ASN A 1 156 ? 210.991 133.998 192.550 1.00 174.62 ? 171  ASN A CA   1 
ATOM   2457 C C    . ASN A 1 156 ? 209.647 134.495 191.999 1.00 174.45 ? 171  ASN A C    1 
ATOM   2458 O O    . ASN A 1 156 ? 209.447 135.693 191.849 1.00 173.64 ? 171  ASN A O    1 
ATOM   2459 C CB   . ASN A 1 156 ? 210.929 133.849 194.077 1.00 173.69 ? 171  ASN A CB   1 
ATOM   2460 C CG   . ASN A 1 156 ? 212.156 133.162 194.644 1.00 176.88 ? 171  ASN A CG   1 
ATOM   2461 O OD1  . ASN A 1 156 ? 212.601 132.154 194.103 1.00 179.48 ? 171  ASN A OD1  1 
ATOM   2462 N ND2  . ASN A 1 156 ? 212.722 133.693 195.716 1.00 178.58 ? 171  ASN A ND2  1 
ATOM   2463 H H    . ASN A 1 156 ? 212.439 135.530 192.920 1.00 175.87 ? 171  ASN A H    1 
ATOM   2464 H HA   . ASN A 1 156 ? 211.183 133.020 192.108 1.00 175.71 ? 171  ASN A HA   1 
ATOM   2465 H HB2  . ASN A 1 156 ? 210.808 134.829 194.535 1.00 175.26 ? 171  ASN A HB2  1 
ATOM   2466 H HB3  . ASN A 1 156 ? 210.064 133.247 194.353 1.00 175.77 ? 171  ASN A HB3  1 
ATOM   2467 H HD21 . ASN A 1 156 ? 212.366 134.566 196.069 1.00 175.80 ? 171  ASN A HD21 1 
ATOM   2468 N N    . GLU A 1 157 ? 208.672 133.605 191.828 1.00 169.60 ? 172  GLU A N    1 
ATOM   2469 C CA   . GLU A 1 157 ? 207.308 133.955 191.422 1.00 168.22 ? 172  GLU A CA   1 
ATOM   2470 C C    . GLU A 1 157 ? 206.540 134.637 192.556 1.00 168.68 ? 172  GLU A C    1 
ATOM   2471 O O    . GLU A 1 157 ? 206.525 134.136 193.680 1.00 170.91 ? 172  GLU A O    1 
ATOM   2472 C CB   . GLU A 1 157 ? 206.573 132.702 190.938 1.00 168.70 ? 172  GLU A CB   1 
ATOM   2473 C CG   . GLU A 1 157 ? 205.166 133.010 190.415 1.00 172.61 ? 172  GLU A CG   1 
ATOM   2474 C CD   . GLU A 1 157 ? 204.754 131.948 189.392 1.00 179.37 ? 172  GLU A CD   1 
ATOM   2475 O OE1  . GLU A 1 157 ? 204.286 130.869 189.819 1.00 179.21 ? 172  GLU A OE1  1 
ATOM   2476 O OE2  . GLU A 1 157 ? 204.956 132.185 188.180 1.00 180.30 ? 172  GLU A OE2  1 
ATOM   2477 H H    . GLU A 1 157 ? 208.873 132.640 192.049 1.00 170.64 ? 172  GLU A H    1 
ATOM   2478 H HA   . GLU A 1 157 ? 207.360 134.658 190.591 1.00 170.32 ? 172  GLU A HA   1 
ATOM   2479 H HB2  . GLU A 1 157 ? 207.163 132.262 190.134 1.00 171.01 ? 172  GLU A HB2  1 
ATOM   2480 H HB3  . GLU A 1 157 ? 206.507 131.973 191.746 1.00 170.40 ? 172  GLU A HB3  1 
ATOM   2481 H HG2  . GLU A 1 157 ? 204.464 133.042 191.249 1.00 171.00 ? 172  GLU A HG2  1 
ATOM   2482 H HG3  . GLU A 1 157 ? 205.169 133.994 189.946 1.00 170.68 ? 172  GLU A HG3  1 
ATOM   2483 N N    . SER A 1 158 ? 205.858 135.746 192.269 1.00 158.03 ? 173  SER A N    1 
ATOM   2484 C CA   . SER A 1 158 ? 204.962 136.387 193.230 1.00 157.44 ? 173  SER A CA   1 
ATOM   2485 C C    . SER A 1 158 ? 203.949 137.283 192.533 1.00 158.22 ? 173  SER A C    1 
ATOM   2486 O O    . SER A 1 158 ? 204.292 138.339 192.003 1.00 161.32 ? 173  SER A O    1 
ATOM   2487 C CB   . SER A 1 158 ? 205.748 137.204 194.257 1.00 156.66 ? 173  SER A CB   1 
ATOM   2488 O OG   . SER A 1 158 ? 206.476 138.260 193.653 1.00 159.19 ? 173  SER A OG   1 
ATOM   2489 H H    . SER A 1 158 ? 205.917 136.142 191.341 1.00 158.40 ? 173  SER A H    1 
ATOM   2490 H HA   . SER A 1 158 ? 204.419 135.615 193.775 1.00 158.08 ? 173  SER A HA   1 
ATOM   2491 H HB2  . SER A 1 158 ? 205.050 137.627 194.979 1.00 158.38 ? 173  SER A HB2  1 
ATOM   2492 H HB3  . SER A 1 158 ? 206.439 136.554 194.795 1.00 158.11 ? 173  SER A HB3  1 
ATOM   2493 H HG   . SER A 1 158 ? 205.902 138.649 192.990 1.00 158.64 ? 173  SER A HG   1 
ATOM   2494 N N    . TRP A 1 159 ? 202.679 136.897 192.577 1.00 142.65 ? 174  TRP A N    1 
ATOM   2495 C CA   . TRP A 1 159 ? 201.566 137.761 192.178 1.00 148.41 ? 174  TRP A CA   1 
ATOM   2496 C C    . TRP A 1 159 ? 200.516 137.922 193.272 1.00 152.12 ? 174  TRP A C    1 
ATOM   2497 O O    . TRP A 1 159 ? 199.748 138.878 193.235 1.00 157.06 ? 174  TRP A O    1 
ATOM   2498 C CB   . TRP A 1 159 ? 200.986 137.278 190.852 1.00 146.28 ? 174  TRP A CB   1 
ATOM   2499 C CG   . TRP A 1 159 ? 200.587 135.846 190.804 1.00 146.09 ? 174  TRP A CG   1 
ATOM   2500 C CD1  . TRP A 1 159 ? 201.384 134.833 190.411 1.00 148.10 ? 174  TRP A CD1  1 
ATOM   2501 C CD2  . TRP A 1 159 ? 199.328 135.238 191.194 1.00 141.76 ? 174  TRP A CD2  1 
ATOM   2502 N NE1  . TRP A 1 159 ? 200.702 133.643 190.521 1.00 143.59 ? 174  TRP A NE1  1 
ATOM   2503 C CE2  . TRP A 1 159 ? 199.426 133.834 190.993 1.00 140.25 ? 174  TRP A CE2  1 
ATOM   2504 C CE3  . TRP A 1 159 ? 198.116 135.733 191.705 1.00 143.80 ? 174  TRP A CE3  1 
ATOM   2505 C CZ2  . TRP A 1 159 ? 198.374 132.960 191.276 1.00 141.41 ? 174  TRP A CZ2  1 
ATOM   2506 C CZ3  . TRP A 1 159 ? 197.056 134.863 192.007 1.00 148.71 ? 174  TRP A CZ3  1 
ATOM   2507 C CH2  . TRP A 1 159 ? 197.179 133.482 191.787 1.00 147.45 ? 174  TRP A CH2  1 
ATOM   2508 H H    . TRP A 1 159 ? 202.470 135.960 192.893 1.00 146.40 ? 174  TRP A H    1 
ATOM   2509 H HA   . TRP A 1 159 ? 201.944 138.771 192.019 1.00 148.30 ? 174  TRP A HA   1 
ATOM   2510 H HB2  . TRP A 1 159 ? 200.115 137.885 190.604 1.00 146.80 ? 174  TRP A HB2  1 
ATOM   2511 H HB3  . TRP A 1 159 ? 201.732 137.446 190.076 1.00 147.55 ? 174  TRP A HB3  1 
ATOM   2512 H HD1  . TRP A 1 159 ? 202.401 134.946 190.064 1.00 147.77 ? 174  TRP A HD1  1 
ATOM   2513 H HE1  . TRP A 1 159 ? 201.104 132.749 190.277 1.00 146.73 ? 174  TRP A HE1  1 
ATOM   2514 H HE3  . TRP A 1 159 ? 198.005 136.794 191.877 1.00 146.79 ? 174  TRP A HE3  1 
ATOM   2515 H HZ2  . TRP A 1 159 ? 198.485 131.898 191.113 1.00 146.57 ? 174  TRP A HZ2  1 
ATOM   2516 H HZ3  . TRP A 1 159 ? 196.138 135.258 192.415 1.00 147.56 ? 174  TRP A HZ3  1 
ATOM   2517 H HH2  . TRP A 1 159 ? 196.355 132.823 192.018 1.00 147.67 ? 174  TRP A HH2  1 
ATOM   2518 N N    . HIS A 1 160 ? 200.551 137.085 194.303 1.00 151.74 ? 175  HIS A N    1 
ATOM   2519 C CA   . HIS A 1 160 ? 199.751 137.251 195.505 1.00 150.40 ? 175  HIS A CA   1 
ATOM   2520 C C    . HIS A 1 160 ? 200.526 136.756 196.727 1.00 149.96 ? 175  HIS A C    1 
ATOM   2521 O O    . HIS A 1 160 ? 201.442 135.943 196.596 1.00 150.00 ? 175  HIS A O    1 
ATOM   2522 C CB   . HIS A 1 160 ? 198.422 136.512 195.336 1.00 149.94 ? 175  HIS A CB   1 
ATOM   2523 C CG   . HIS A 1 160 ? 198.531 135.026 195.550 1.00 150.81 ? 175  HIS A CG   1 
ATOM   2524 N ND1  . HIS A 1 160 ? 198.042 134.356 196.641 1.00 153.32 ? 175  HIS A ND1  1 
ATOM   2525 C CD2  . HIS A 1 160 ? 199.179 134.110 194.770 1.00 152.24 ? 175  HIS A CD2  1 
ATOM   2526 C CE1  . HIS A 1 160 ? 198.375 133.062 196.524 1.00 150.27 ? 175  HIS A CE1  1 
ATOM   2527 N NE2  . HIS A 1 160 ? 199.082 132.862 195.399 1.00 150.40 ? 175  HIS A NE2  1 
ATOM   2528 H H    . HIS A 1 160 ? 201.242 136.348 194.320 1.00 151.22 ? 175  HIS A H    1 
ATOM   2529 H HA   . HIS A 1 160 ? 199.548 138.314 195.640 1.00 152.20 ? 175  HIS A HA   1 
ATOM   2530 H HB2  . HIS A 1 160 ? 197.719 136.906 196.070 1.00 151.92 ? 175  HIS A HB2  1 
ATOM   2531 H HB3  . HIS A 1 160 ? 198.003 136.712 194.350 1.00 151.77 ? 175  HIS A HB3  1 
ATOM   2532 H HD1  . HIS A 1 160 ? 197.440 134.754 197.346 1.00 152.58 ? 175  HIS A HD1  1 
ATOM   2533 H HD2  . HIS A 1 160 ? 199.689 134.319 193.841 1.00 151.54 ? 175  HIS A HD2  1 
ATOM   2534 H HE1  . HIS A 1 160 ? 198.096 132.289 197.224 1.00 151.45 ? 175  HIS A HE1  1 
ATOM   2535 N N    . PHE A 1 161 ? 200.156 137.220 197.917 1.00 162.27 ? 176  PHE A N    1 
ATOM   2536 C CA   . PHE A 1 161 ? 200.737 136.762 199.177 1.00 161.42 ? 176  PHE A CA   1 
ATOM   2537 C C    . PHE A 1 161 ? 199.638 136.376 200.164 1.00 163.84 ? 176  PHE A C    1 
ATOM   2538 O O    . PHE A 1 161 ? 199.294 137.127 201.072 1.00 167.78 ? 176  PHE A O    1 
ATOM   2539 C CB   . PHE A 1 161 ? 201.706 137.812 199.728 1.00 161.52 ? 176  PHE A CB   1 
ATOM   2540 C CG   . PHE A 1 161 ? 202.446 137.323 200.957 1.00 163.16 ? 176  PHE A CG   1 
ATOM   2541 C CD1  . PHE A 1 161 ? 203.529 136.437 200.812 1.00 164.07 ? 176  PHE A CD1  1 
ATOM   2542 C CD2  . PHE A 1 161 ? 202.023 137.694 202.244 1.00 162.30 ? 176  PHE A CD2  1 
ATOM   2543 C CE1  . PHE A 1 161 ? 204.184 135.931 201.947 1.00 166.15 ? 176  PHE A CE1  1 
ATOM   2544 C CE2  . PHE A 1 161 ? 202.677 137.188 203.380 1.00 161.54 ? 176  PHE A CE2  1 
ATOM   2545 C CZ   . PHE A 1 161 ? 203.758 136.305 203.231 1.00 164.48 ? 176  PHE A CZ   1 
ATOM   2546 H H    . PHE A 1 161 ? 199.423 137.914 197.949 1.00 163.20 ? 176  PHE A H    1 
ATOM   2547 H HA   . PHE A 1 161 ? 201.320 135.858 198.999 1.00 162.10 ? 176  PHE A HA   1 
ATOM   2548 H HB2  . PHE A 1 161 ? 202.442 138.052 198.961 1.00 162.87 ? 176  PHE A HB2  1 
ATOM   2549 H HB3  . PHE A 1 161 ? 201.162 138.727 199.966 1.00 162.50 ? 176  PHE A HB3  1 
ATOM   2550 H HD1  . PHE A 1 161 ? 203.853 136.140 199.825 1.00 162.59 ? 176  PHE A HD1  1 
ATOM   2551 H HD2  . PHE A 1 161 ? 201.184 138.362 202.364 1.00 162.93 ? 176  PHE A HD2  1 
ATOM   2552 H HE1  . PHE A 1 161 ? 205.014 135.250 201.830 1.00 163.30 ? 176  PHE A HE1  1 
ATOM   2553 H HE2  . PHE A 1 161 ? 202.346 137.477 204.366 1.00 162.48 ? 176  PHE A HE2  1 
ATOM   2554 H HZ   . PHE A 1 161 ? 204.261 135.914 204.103 1.00 162.98 ? 176  PHE A HZ   1 
ATOM   2555 N N    . ASP A 1 162 ? 199.066 135.190 199.979 1.00 171.19 ? 177  ASP A N    1 
ATOM   2556 C CA   . ASP A 1 162 ? 198.123 134.601 200.930 1.00 172.11 ? 177  ASP A CA   1 
ATOM   2557 C C    . ASP A 1 162 ? 198.780 133.407 201.610 1.00 171.50 ? 177  ASP A C    1 
ATOM   2558 O O    . ASP A 1 162 ? 199.142 132.424 200.962 1.00 169.41 ? 177  ASP A O    1 
ATOM   2559 C CB   . ASP A 1 162 ? 196.809 134.240 200.231 1.00 171.02 ? 177  ASP A CB   1 
ATOM   2560 C CG   . ASP A 1 162 ? 196.163 135.476 199.607 1.00 177.25 ? 177  ASP A CG   1 
ATOM   2561 O OD1  . ASP A 1 162 ? 195.617 136.317 200.354 1.00 179.22 ? 177  ASP A OD1  1 
ATOM   2562 O OD2  . ASP A 1 162 ? 196.249 135.625 198.368 1.00 180.37 ? 177  ASP A OD2  1 
ATOM   2563 H H    . ASP A 1 162 ? 199.392 134.609 199.220 1.00 170.99 ? 177  ASP A H    1 
ATOM   2564 H HA   . ASP A 1 162 ? 197.873 135.327 201.703 1.00 172.08 ? 177  ASP A HA   1 
ATOM   2565 H HB2  . ASP A 1 162 ? 196.998 133.489 199.463 1.00 171.60 ? 177  ASP A HB2  1 
ATOM   2566 H HB3  . ASP A 1 162 ? 196.124 133.813 200.962 1.00 171.51 ? 177  ASP A HB3  1 
ATOM   2567 N N    . LYS A 1 163 ? 198.978 133.515 202.925 1.00 179.61 ? 178  LYS A N    1 
ATOM   2568 C CA   . LYS A 1 163 ? 199.699 132.510 203.707 1.00 180.54 ? 178  LYS A CA   1 
ATOM   2569 C C    . LYS A 1 163 ? 198.805 131.324 204.064 1.00 181.95 ? 178  LYS A C    1 
ATOM   2570 O O    . LYS A 1 163 ? 199.189 130.172 203.867 1.00 180.54 ? 178  LYS A O    1 
ATOM   2571 C CB   . LYS A 1 163 ? 200.307 133.193 204.937 1.00 178.01 ? 178  LYS A CB   1 
ATOM   2572 C CG   . LYS A 1 163 ? 201.262 132.238 205.664 1.00 179.72 ? 178  LYS A CG   1 
ATOM   2573 C CD   . LYS A 1 163 ? 202.018 132.959 206.783 1.00 179.22 ? 178  LYS A CD   1 
ATOM   2574 C CE   . LYS A 1 163 ? 202.997 131.984 207.444 1.00 178.93 ? 178  LYS A CE   1 
ATOM   2575 N NZ   . LYS A 1 163 ? 203.786 132.646 208.509 1.00 179.27 ? 178  LYS A NZ   1 
ATOM   2576 H H    . LYS A 1 163 ? 198.682 134.365 203.383 1.00 178.51 ? 178  LYS A H    1 
ATOM   2577 H HA   . LYS A 1 163 ? 200.514 132.115 203.102 1.00 178.96 ? 178  LYS A HA   1 
ATOM   2578 H HB2  . LYS A 1 163 ? 200.871 134.067 204.610 1.00 178.03 ? 178  LYS A HB2  1 
ATOM   2579 H HB3  . LYS A 1 163 ? 199.522 133.518 205.619 1.00 178.48 ? 178  LYS A HB3  1 
ATOM   2580 H HG2  . LYS A 1 163 ? 200.696 131.409 206.090 1.00 178.59 ? 178  LYS A HG2  1 
ATOM   2581 H HG3  . LYS A 1 163 ? 201.983 131.844 204.948 1.00 179.13 ? 178  LYS A HG3  1 
ATOM   2582 H HD2  . LYS A 1 163 ? 202.569 133.800 206.360 1.00 178.58 ? 178  LYS A HD2  1 
ATOM   2583 H HD3  . LYS A 1 163 ? 201.307 133.329 207.521 1.00 178.73 ? 178  LYS A HD3  1 
ATOM   2584 H HE2  . LYS A 1 163 ? 202.432 131.151 207.861 1.00 178.60 ? 178  LYS A HE2  1 
ATOM   2585 H HE3  . LYS A 1 163 ? 203.664 131.587 206.680 1.00 178.88 ? 178  LYS A HE3  1 
ATOM   2586 H HZ1  . LYS A 1 163 ? 204.426 131.995 208.941 1.00 178.76 ? 178  LYS A HZ1  1 
ATOM   2587 H HZ2  . LYS A 1 163 ? 204.330 133.411 208.136 1.00 178.92 ? 178  LYS A HZ2  1 
ATOM   2588 H HZ3  . LYS A 1 163 ? 203.184 133.013 209.232 1.00 178.91 ? 178  LYS A HZ3  1 
ATOM   2589 N N    . SER A 1 164 ? 197.602 131.612 204.545 1.00 191.58 ? 179  SER A N    1 
ATOM   2590 C CA   . SER A 1 164 ? 196.465 130.689 204.557 1.00 189.75 ? 179  SER A CA   1 
ATOM   2591 C C    . SER A 1 164 ? 195.699 130.768 203.231 1.00 192.15 ? 179  SER A C    1 
ATOM   2592 O O    . SER A 1 164 ? 195.775 131.764 202.514 1.00 193.49 ? 179  SER A O    1 
ATOM   2593 C CB   . SER A 1 164 ? 195.559 131.010 205.751 1.00 186.58 ? 179  SER A CB   1 
ATOM   2594 O OG   . SER A 1 164 ? 195.174 132.376 205.759 1.00 188.98 ? 179  SER A OG   1 
ATOM   2595 H H    . SER A 1 164 ? 197.382 132.588 204.686 1.00 188.56 ? 179  SER A H    1 
ATOM   2596 H HA   . SER A 1 164 ? 196.824 129.666 204.677 1.00 188.33 ? 179  SER A HA   1 
ATOM   2597 H HB2  . SER A 1 164 ? 194.673 130.378 205.712 1.00 188.14 ? 179  SER A HB2  1 
ATOM   2598 H HB3  . SER A 1 164 ? 196.099 130.788 206.672 1.00 188.16 ? 179  SER A HB3  1 
ATOM   2599 H HG   . SER A 1 164 ? 194.563 132.508 206.488 1.00 188.63 ? 179  SER A HG   1 
ATOM   2600 N N    . GLU A 1 165 ? 194.961 129.722 202.867 1.00 184.68 ? 180  GLU A N    1 
ATOM   2601 C CA   . GLU A 1 165 ? 194.212 129.686 201.605 1.00 185.60 ? 180  GLU A CA   1 
ATOM   2602 C C    . GLU A 1 165 ? 193.062 130.720 201.598 1.00 183.75 ? 180  GLU A C    1 
ATOM   2603 O O    . GLU A 1 165 ? 192.257 130.727 202.533 1.00 181.92 ? 180  GLU A O    1 
ATOM   2604 C CB   . GLU A 1 165 ? 193.682 128.258 201.398 1.00 183.26 ? 180  GLU A CB   1 
ATOM   2605 C CG   . GLU A 1 165 ? 192.952 128.027 200.065 1.00 185.54 ? 180  GLU A CG   1 
ATOM   2606 C CD   . GLU A 1 165 ? 193.864 128.051 198.826 1.00 187.26 ? 180  GLU A CD   1 
ATOM   2607 O OE1  . GLU A 1 165 ? 195.092 128.253 198.956 1.00 187.24 ? 180  GLU A OE1  1 
ATOM   2608 O OE2  . GLU A 1 165 ? 193.340 127.837 197.708 1.00 184.93 ? 180  GLU A OE2  1 
ATOM   2609 H H    . GLU A 1 165 ? 194.914 128.916 203.475 1.00 183.05 ? 180  GLU A H    1 
ATOM   2610 H HA   . GLU A 1 165 ? 194.911 129.912 200.800 1.00 183.69 ? 180  GLU A HA   1 
ATOM   2611 H HB2  . GLU A 1 165 ? 194.507 127.550 201.476 1.00 182.93 ? 180  GLU A HB2  1 
ATOM   2612 H HB3  . GLU A 1 165 ? 192.985 128.030 202.204 1.00 182.89 ? 180  GLU A HB3  1 
ATOM   2613 H HG2  . GLU A 1 165 ? 192.473 127.048 200.121 1.00 183.24 ? 180  GLU A HG2  1 
ATOM   2614 H HG3  . GLU A 1 165 ? 192.160 128.766 199.956 1.00 183.48 ? 180  GLU A HG3  1 
ATOM   2615 N N    . PRO A 1 166 ? 192.934 131.585 200.576 1.00 161.95 ? 181  PRO A N    1 
ATOM   2616 C CA   . PRO A 1 166 ? 191.857 132.569 200.495 1.00 158.28 ? 181  PRO A CA   1 
ATOM   2617 C C    . PRO A 1 166 ? 190.518 131.936 200.127 1.00 158.81 ? 181  PRO A C    1 
ATOM   2618 O O    . PRO A 1 166 ? 190.452 130.840 199.571 1.00 161.24 ? 181  PRO A O    1 
ATOM   2619 C CB   . PRO A 1 166 ? 192.303 133.573 199.436 1.00 161.43 ? 181  PRO A CB   1 
ATOM   2620 C CG   . PRO A 1 166 ? 193.162 132.724 198.504 1.00 164.56 ? 181  PRO A CG   1 
ATOM   2621 C CD   . PRO A 1 166 ? 193.830 131.726 199.445 1.00 163.24 ? 181  PRO A CD   1 
ATOM   2622 H HA   . PRO A 1 166 ? 191.751 133.085 201.449 1.00 162.35 ? 181  PRO A HA   1 
ATOM   2623 H HB2  . PRO A 1 166 ? 191.466 134.031 198.909 1.00 162.23 ? 181  PRO A HB2  1 
ATOM   2624 H HB3  . PRO A 1 166 ? 192.923 134.339 199.901 1.00 162.59 ? 181  PRO A HB3  1 
ATOM   2625 H HG2  . PRO A 1 166 ? 192.524 132.189 197.802 1.00 162.70 ? 181  PRO A HG2  1 
ATOM   2626 H HG3  . PRO A 1 166 ? 193.897 133.327 197.970 1.00 162.98 ? 181  PRO A HG3  1 
ATOM   2627 H HD2  . PRO A 1 166 ? 193.979 130.777 198.929 1.00 163.28 ? 181  PRO A HD2  1 
ATOM   2628 H HD3  . PRO A 1 166 ? 194.786 132.123 199.787 1.00 163.29 ? 181  PRO A HD3  1 
ATOM   2629 N N    . LEU A 1 167 ? 189.430 132.652 200.395 1.00 161.92 ? 182  LEU A N    1 
ATOM   2630 C CA   . LEU A 1 167 ? 188.093 132.236 199.985 1.00 167.53 ? 182  LEU A CA   1 
ATOM   2631 C C    . LEU A 1 167 ? 187.942 132.311 198.461 1.00 170.32 ? 182  LEU A C    1 
ATOM   2632 O O    . LEU A 1 167 ? 188.282 133.334 197.863 1.00 173.80 ? 182  LEU A O    1 
ATOM   2633 C CB   . LEU A 1 167 ? 187.071 133.122 200.709 1.00 168.06 ? 182  LEU A CB   1 
ATOM   2634 C CG   . LEU A 1 167 ? 185.624 132.629 200.594 1.00 168.56 ? 182  LEU A CG   1 
ATOM   2635 C CD1  . LEU A 1 167 ? 185.409 131.268 201.254 1.00 166.23 ? 182  LEU A CD1  1 
ATOM   2636 C CD2  . LEU A 1 167 ? 184.703 133.637 201.275 1.00 164.56 ? 182  LEU A CD2  1 
ATOM   2637 H H    . LEU A 1 167 ? 189.538 133.544 200.858 1.00 165.32 ? 182  LEU A H    1 
ATOM   2638 H HA   . LEU A 1 167 ? 187.958 131.201 200.299 1.00 166.19 ? 182  LEU A HA   1 
ATOM   2639 H HB2  . LEU A 1 167 ? 187.330 133.165 201.767 1.00 166.05 ? 182  LEU A HB2  1 
ATOM   2640 H HB3  . LEU A 1 167 ? 187.136 134.133 200.306 1.00 165.84 ? 182  LEU A HB3  1 
ATOM   2641 H HG   . LEU A 1 167 ? 185.344 132.564 199.542 1.00 166.23 ? 182  LEU A HG   1 
ATOM   2642 H HD11 . LEU A 1 167 ? 185.954 130.492 200.717 1.00 166.10 ? 182  LEU A HD11 1 
ATOM   2643 H HD12 . LEU A 1 167 ? 184.350 131.015 201.231 1.00 165.92 ? 182  LEU A HD12 1 
ATOM   2644 H HD13 . LEU A 1 167 ? 185.746 131.299 202.291 1.00 165.84 ? 182  LEU A HD13 1 
ATOM   2645 H HD21 . LEU A 1 167 ? 184.840 134.625 200.837 1.00 165.62 ? 182  LEU A HD21 1 
ATOM   2646 H HD22 . LEU A 1 167 ? 183.663 133.332 201.144 1.00 165.62 ? 182  LEU A HD22 1 
ATOM   2647 H HD23 . LEU A 1 167 ? 184.929 133.687 202.339 1.00 166.08 ? 182  LEU A HD23 1 
ATOM   2648 N N    . CYS A 1 168 ? 187.399 131.266 197.836 1.00 163.67 ? 183  CYS A N    1 
ATOM   2649 C CA   . CYS A 1 168 ? 187.263 131.171 196.383 1.00 162.25 ? 183  CYS A CA   1 
ATOM   2650 C C    . CYS A 1 168 ? 185.832 130.856 195.956 1.00 156.33 ? 183  CYS A C    1 
ATOM   2651 O O    . CYS A 1 168 ? 185.216 129.927 196.473 1.00 155.63 ? 183  CYS A O    1 
ATOM   2652 C CB   . CYS A 1 168 ? 188.219 130.107 195.845 1.00 166.98 ? 183  CYS A CB   1 
ATOM   2653 S SG   . CYS A 1 168 ? 189.976 130.420 196.144 1.00 193.52 ? 183  CYS A SG   1 
ATOM   2654 H H    . CYS A 1 168 ? 187.130 130.461 198.384 1.00 164.95 ? 183  CYS A H    1 
ATOM   2655 H HA   . CYS A 1 168 ? 187.538 132.123 195.928 1.00 165.45 ? 183  CYS A HA   1 
ATOM   2656 H HB2  . CYS A 1 168 ? 187.964 129.154 196.308 1.00 165.23 ? 183  CYS A HB2  1 
ATOM   2657 H HB3  . CYS A 1 168 ? 188.072 130.001 194.770 1.00 165.37 ? 183  CYS A HB3  1 
ATOM   2658 N N    . LEU A 1 169 ? 185.322 131.587 194.965 1.00 145.94 ? 184  LEU A N    1 
ATOM   2659 C CA   . LEU A 1 169 ? 184.056 131.274 194.302 1.00 149.93 ? 184  LEU A CA   1 
ATOM   2660 C C    . LEU A 1 169 ? 184.224 130.162 193.264 1.00 152.76 ? 184  LEU A C    1 
ATOM   2661 O O    . LEU A 1 169 ? 183.289 129.407 193.010 1.00 154.72 ? 184  LEU A O    1 
ATOM   2662 C CB   . LEU A 1 169 ? 183.506 132.526 193.602 1.00 148.59 ? 184  LEU A CB   1 
ATOM   2663 C CG   . LEU A 1 169 ? 183.186 133.696 194.535 1.00 146.97 ? 184  LEU A CG   1 
ATOM   2664 C CD1  . LEU A 1 169 ? 182.827 134.921 193.704 1.00 145.06 ? 184  LEU A CD1  1 
ATOM   2665 C CD2  . LEU A 1 169 ? 182.023 133.379 195.470 1.00 145.33 ? 184  LEU A CD2  1 
ATOM   2666 H H    . LEU A 1 169 ? 185.903 132.309 194.563 1.00 148.91 ? 184  LEU A H    1 
ATOM   2667 H HA   . LEU A 1 169 ? 183.330 130.926 195.036 1.00 148.72 ? 184  LEU A HA   1 
ATOM   2668 H HB2  . LEU A 1 169 ? 184.231 132.857 192.859 1.00 148.38 ? 184  LEU A HB2  1 
ATOM   2669 H HB3  . LEU A 1 169 ? 182.589 132.252 193.082 1.00 148.15 ? 184  LEU A HB3  1 
ATOM   2670 H HG   . LEU A 1 169 ? 184.069 133.927 195.132 1.00 148.19 ? 184  LEU A HG   1 
ATOM   2671 H HD11 . LEU A 1 169 ? 183.676 135.205 193.083 1.00 147.51 ? 184  LEU A HD11 1 
ATOM   2672 H HD12 . LEU A 1 169 ? 182.586 135.754 194.364 1.00 148.42 ? 184  LEU A HD12 1 
ATOM   2673 H HD13 . LEU A 1 169 ? 181.967 134.705 193.072 1.00 148.06 ? 184  LEU A HD13 1 
ATOM   2674 H HD21 . LEU A 1 169 ? 182.289 132.555 196.133 1.00 148.13 ? 184  LEU A HD21 1 
ATOM   2675 H HD22 . LEU A 1 169 ? 181.140 133.111 194.892 1.00 148.16 ? 184  LEU A HD22 1 
ATOM   2676 H HD23 . LEU A 1 169 ? 181.800 134.253 196.081 1.00 147.90 ? 184  LEU A HD23 1 
ATOM   2677 N N    . PHE A 1 170 ? 185.404 130.066 192.650 1.00 156.81 ? 185  PHE A N    1 
ATOM   2678 C CA   . PHE A 1 170 ? 185.677 129.140 191.557 1.00 152.26 ? 185  PHE A CA   1 
ATOM   2679 C C    . PHE A 1 170 ? 187.132 128.686 191.568 1.00 152.14 ? 185  PHE A C    1 
ATOM   2680 O O    . PHE A 1 170 ? 188.031 129.471 191.868 1.00 157.19 ? 185  PHE A O    1 
ATOM   2681 C CB   . PHE A 1 170 ? 185.335 129.847 190.244 1.00 150.70 ? 185  PHE A CB   1 
ATOM   2682 C CG   . PHE A 1 170 ? 185.332 128.964 189.021 1.00 149.54 ? 185  PHE A CG   1 
ATOM   2683 C CD1  . PHE A 1 170 ? 184.273 128.067 188.815 1.00 147.12 ? 185  PHE A CD1  1 
ATOM   2684 C CD2  . PHE A 1 170 ? 186.362 129.064 188.075 1.00 150.81 ? 185  PHE A CD2  1 
ATOM   2685 C CE1  . PHE A 1 170 ? 184.235 127.279 187.654 1.00 149.11 ? 185  PHE A CE1  1 
ATOM   2686 C CE2  . PHE A 1 170 ? 186.322 128.279 186.913 1.00 151.62 ? 185  PHE A CE2  1 
ATOM   2687 C CZ   . PHE A 1 170 ? 185.256 127.393 186.700 1.00 151.01 ? 185  PHE A CZ   1 
ATOM   2688 H H    . PHE A 1 170 ? 186.138 130.708 192.914 1.00 151.66 ? 185  PHE A H    1 
ATOM   2689 H HA   . PHE A 1 170 ? 185.041 128.259 191.658 1.00 150.44 ? 185  PHE A HA   1 
ATOM   2690 H HB2  . PHE A 1 170 ? 184.341 130.284 190.335 1.00 151.05 ? 185  PHE A HB2  1 
ATOM   2691 H HB3  . PHE A 1 170 ? 186.038 130.665 190.087 1.00 150.59 ? 185  PHE A HB3  1 
ATOM   2692 H HD1  . PHE A 1 170 ? 183.475 127.996 189.539 1.00 149.97 ? 185  PHE A HD1  1 
ATOM   2693 H HD2  . PHE A 1 170 ? 187.177 129.755 188.227 1.00 150.36 ? 185  PHE A HD2  1 
ATOM   2694 H HE1  . PHE A 1 170 ? 183.412 126.600 187.489 1.00 150.54 ? 185  PHE A HE1  1 
ATOM   2695 H HE2  . PHE A 1 170 ? 187.102 128.373 186.171 1.00 150.70 ? 185  PHE A HE2  1 
ATOM   2696 H HZ   . PHE A 1 170 ? 185.218 126.809 185.792 1.00 150.70 ? 185  PHE A HZ   1 
ATOM   2697 N N    . LYS A 1 171 ? 187.370 127.434 191.190 1.00 147.57 ? 186  LYS A N    1 
ATOM   2698 C CA   . LYS A 1 171 ? 188.693 126.830 191.029 1.00 150.37 ? 186  LYS A CA   1 
ATOM   2699 C C    . LYS A 1 171 ? 188.550 125.592 190.154 1.00 153.06 ? 186  LYS A C    1 
ATOM   2700 O O    . LYS A 1 171 ? 188.001 124.589 190.608 1.00 150.49 ? 186  LYS A O    1 
ATOM   2701 C CB   . LYS A 1 171 ? 189.260 126.491 192.420 1.00 146.09 ? 186  LYS A CB   1 
ATOM   2702 C CG   . LYS A 1 171 ? 190.593 125.732 192.341 1.00 151.09 ? 186  LYS A CG   1 
ATOM   2703 C CD   . LYS A 1 171 ? 191.174 125.388 193.717 1.00 155.83 ? 186  LYS A CD   1 
ATOM   2704 C CE   . LYS A 1 171 ? 191.626 126.626 194.502 1.00 155.89 ? 186  LYS A CE   1 
ATOM   2705 N NZ   . LYS A 1 171 ? 192.310 126.224 195.755 1.00 159.05 ? 186  LYS A NZ   1 
ATOM   2706 H H    . LYS A 1 171 ? 186.566 126.859 190.976 1.00 150.86 ? 186  LYS A H    1 
ATOM   2707 H HA   . LYS A 1 171 ? 189.365 127.531 190.536 1.00 152.15 ? 186  LYS A HA   1 
ATOM   2708 H HB2  . LYS A 1 171 ? 189.411 127.418 192.973 1.00 150.98 ? 186  LYS A HB2  1 
ATOM   2709 H HB3  . LYS A 1 171 ? 188.542 125.880 192.967 1.00 150.90 ? 186  LYS A HB3  1 
ATOM   2710 H HG2  . LYS A 1 171 ? 190.445 124.793 191.809 1.00 151.75 ? 186  LYS A HG2  1 
ATOM   2711 H HG3  . LYS A 1 171 ? 191.322 126.322 191.785 1.00 151.51 ? 186  LYS A HG3  1 
ATOM   2712 H HD2  . LYS A 1 171 ? 190.430 124.839 194.293 1.00 152.35 ? 186  LYS A HD2  1 
ATOM   2713 H HD3  . LYS A 1 171 ? 192.034 124.737 193.560 1.00 152.46 ? 186  LYS A HD3  1 
ATOM   2714 H HE2  . LYS A 1 171 ? 192.306 127.208 193.878 1.00 152.25 ? 186  LYS A HE2  1 
ATOM   2715 H HE3  . LYS A 1 171 ? 190.758 127.244 194.727 1.00 152.27 ? 186  LYS A HE3  1 
ATOM   2716 H HZ1  . LYS A 1 171 ? 192.617 127.017 196.300 1.00 153.14 ? 186  LYS A HZ1  1 
ATOM   2717 H HZ2  . LYS A 1 171 ? 193.133 125.671 195.560 1.00 153.13 ? 186  LYS A HZ2  1 
ATOM   2718 H HZ3  . LYS A 1 171 ? 191.700 125.679 196.347 1.00 153.20 ? 186  LYS A HZ3  1 
ATOM   2719 N N    . LYS A 1 172 ? 189.025 125.644 188.911 1.00 159.97 ? 187  LYS A N    1 
ATOM   2720 C CA   . LYS A 1 172 ? 189.018 124.511 187.972 1.00 154.28 ? 187  LYS A CA   1 
ATOM   2721 C C    . LYS A 1 172 ? 190.242 124.529 187.074 1.00 155.52 ? 187  LYS A C    1 
ATOM   2722 O O    . LYS A 1 172 ? 190.808 125.582 186.801 1.00 164.56 ? 187  LYS A O    1 
ATOM   2723 C CB   . LYS A 1 172 ? 187.749 124.498 187.101 1.00 153.09 ? 187  LYS A CB   1 
ATOM   2724 C CG   . LYS A 1 172 ? 186.518 124.020 187.881 1.00 153.84 ? 187  LYS A CG   1 
ATOM   2725 C CD   . LYS A 1 172 ? 185.326 123.650 186.989 1.00 158.76 ? 187  LYS A CD   1 
ATOM   2726 C CE   . LYS A 1 172 ? 185.602 122.384 186.167 1.00 160.44 ? 187  LYS A CE   1 
ATOM   2727 N NZ   . LYS A 1 172 ? 184.384 121.911 185.464 1.00 163.88 ? 187  LYS A NZ   1 
ATOM   2728 H H    . LYS A 1 172 ? 189.467 126.501 188.610 1.00 156.67 ? 187  LYS A H    1 
ATOM   2729 H HA   . LYS A 1 172 ? 189.063 123.579 188.536 1.00 155.79 ? 187  LYS A HA   1 
ATOM   2730 H HB2  . LYS A 1 172 ? 187.565 125.493 186.694 1.00 156.01 ? 187  LYS A HB2  1 
ATOM   2731 H HB3  . LYS A 1 172 ? 187.910 123.820 186.264 1.00 155.82 ? 187  LYS A HB3  1 
ATOM   2732 H HG2  . LYS A 1 172 ? 186.781 123.147 188.478 1.00 155.53 ? 187  LYS A HG2  1 
ATOM   2733 H HG3  . LYS A 1 172 ? 186.204 124.817 188.557 1.00 155.77 ? 187  LYS A HG3  1 
ATOM   2734 H HD2  . LYS A 1 172 ? 184.466 123.472 187.636 1.00 156.51 ? 187  LYS A HD2  1 
ATOM   2735 H HD3  . LYS A 1 172 ? 185.091 124.481 186.324 1.00 156.64 ? 187  LYS A HD3  1 
ATOM   2736 H HE2  . LYS A 1 172 ? 186.391 122.594 185.444 1.00 156.42 ? 187  LYS A HE2  1 
ATOM   2737 H HE3  . LYS A 1 172 ? 185.962 121.605 186.839 1.00 156.76 ? 187  LYS A HE3  1 
ATOM   2738 H HZ1  . LYS A 1 172 ? 184.579 121.080 184.923 1.00 157.16 ? 187  LYS A HZ1  1 
ATOM   2739 H HZ2  . LYS A 1 172 ? 183.654 121.680 186.122 1.00 157.66 ? 187  LYS A HZ2  1 
ATOM   2740 H HZ3  . LYS A 1 172 ? 184.023 122.613 184.834 1.00 157.04 ? 187  LYS A HZ3  1 
ATOM   2741 N N    . ASN A 1 173 ? 190.588 123.359 186.557 1.00 140.32 ? 188  ASN A N    1 
ATOM   2742 C CA   . ASN A 1 173 ? 191.631 123.192 185.560 1.00 143.79 ? 188  ASN A CA   1 
ATOM   2743 C C    . ASN A 1 173 ? 191.006 122.735 184.249 1.00 145.78 ? 188  ASN A C    1 
ATOM   2744 O O    . ASN A 1 173 ? 190.203 121.804 184.241 1.00 148.31 ? 188  ASN A O    1 
ATOM   2745 C CB   . ASN A 1 173 ? 192.654 122.176 186.073 1.00 144.15 ? 188  ASN A CB   1 
ATOM   2746 C CG   . ASN A 1 173 ? 193.484 122.705 187.221 1.00 147.15 ? 188  ASN A CG   1 
ATOM   2747 O OD1  . ASN A 1 173 ? 193.326 123.839 187.647 1.00 148.60 ? 188  ASN A OD1  1 
ATOM   2748 N ND2  . ASN A 1 173 ? 194.362 121.867 187.735 1.00 148.29 ? 188  ASN A ND2  1 
ATOM   2749 H H    . ASN A 1 173 ? 190.039 122.547 186.803 1.00 146.19 ? 188  ASN A H    1 
ATOM   2750 H HA   . ASN A 1 173 ? 192.138 124.139 185.378 1.00 146.82 ? 188  ASN A HA   1 
ATOM   2751 H HB2  . ASN A 1 173 ? 192.143 121.269 186.393 1.00 146.35 ? 188  ASN A HB2  1 
ATOM   2752 H HB3  . ASN A 1 173 ? 193.328 121.907 185.259 1.00 146.33 ? 188  ASN A HB3  1 
ATOM   2753 H HD21 . ASN A 1 173 ? 194.444 120.940 187.343 1.00 146.33 ? 188  ASN A HD21 1 
ATOM   2754 N N    . PHE A 1 174 ? 191.493 123.265 183.138 1.00 142.38 ? 189  PHE A N    1 
ATOM   2755 C CA   . PHE A 1 174 ? 191.110 122.834 181.801 1.00 141.39 ? 189  PHE A CA   1 
ATOM   2756 C C    . PHE A 1 174 ? 192.373 122.491 181.028 1.00 145.18 ? 189  PHE A C    1 
ATOM   2757 O O    . PHE A 1 174 ? 193.327 123.258 181.051 1.00 152.24 ? 189  PHE A O    1 
ATOM   2758 C CB   . PHE A 1 174 ? 190.305 123.949 181.132 1.00 140.36 ? 189  PHE A CB   1 
ATOM   2759 C CG   . PHE A 1 174 ? 189.087 124.377 181.924 1.00 142.35 ? 189  PHE A CG   1 
ATOM   2760 C CD1  . PHE A 1 174 ? 187.884 123.664 181.799 1.00 142.90 ? 189  PHE A CD1  1 
ATOM   2761 C CD2  . PHE A 1 174 ? 189.156 125.480 182.790 1.00 145.04 ? 189  PHE A CD2  1 
ATOM   2762 C CE1  . PHE A 1 174 ? 186.751 124.062 182.524 1.00 141.73 ? 189  PHE A CE1  1 
ATOM   2763 C CE2  . PHE A 1 174 ? 188.025 125.872 183.523 1.00 148.54 ? 189  PHE A CE2  1 
ATOM   2764 C CZ   . PHE A 1 174 ? 186.821 125.166 183.388 1.00 144.78 ? 189  PHE A CZ   1 
ATOM   2765 H H    . PHE A 1 174 ? 192.168 124.014 183.211 1.00 144.89 ? 189  PHE A H    1 
ATOM   2766 H HA   . PHE A 1 174 ? 190.485 121.943 181.849 1.00 144.62 ? 189  PHE A HA   1 
ATOM   2767 H HB2  . PHE A 1 174 ? 190.949 124.815 180.983 1.00 143.77 ? 189  PHE A HB2  1 
ATOM   2768 H HB3  . PHE A 1 174 ? 189.983 123.607 180.148 1.00 144.36 ? 189  PHE A HB3  1 
ATOM   2769 H HD1  . PHE A 1 174 ? 187.826 122.817 181.133 1.00 144.93 ? 189  PHE A HD1  1 
ATOM   2770 H HD2  . PHE A 1 174 ? 190.081 126.029 182.892 1.00 144.40 ? 189  PHE A HD2  1 
ATOM   2771 H HE1  . PHE A 1 174 ? 185.822 123.523 182.410 1.00 144.37 ? 189  PHE A HE1  1 
ATOM   2772 H HE2  . PHE A 1 174 ? 188.079 126.722 184.188 1.00 145.45 ? 189  PHE A HE2  1 
ATOM   2773 H HZ   . PHE A 1 174 ? 185.946 125.476 183.940 1.00 144.72 ? 189  PHE A HZ   1 
ATOM   2774 N N    . THR A 1 175 ? 192.440 121.347 180.361 1.00 155.92 ? 190  THR A N    1 
ATOM   2775 C CA   . THR A 1 175 ? 193.610 121.025 179.536 1.00 159.82 ? 190  THR A CA   1 
ATOM   2776 C C    . THR A 1 175 ? 193.553 121.758 178.204 1.00 156.06 ? 190  THR A C    1 
ATOM   2777 O O    . THR A 1 175 ? 192.476 122.026 177.679 1.00 152.06 ? 190  THR A O    1 
ATOM   2778 C CB   . THR A 1 175 ? 193.754 119.521 179.308 1.00 158.08 ? 190  THR A CB   1 
ATOM   2779 O OG1  . THR A 1 175 ? 192.556 118.978 178.805 1.00 159.83 ? 190  THR A OG1  1 
ATOM   2780 C CG2  . THR A 1 175 ? 194.092 118.794 180.606 1.00 152.69 ? 190  THR A CG2  1 
ATOM   2781 H H    . THR A 1 175 ? 191.645 120.726 180.327 1.00 154.52 ? 190  THR A H    1 
ATOM   2782 H HA   . THR A 1 175 ? 194.508 121.356 180.055 1.00 155.42 ? 190  THR A HA   1 
ATOM   2783 H HB   . THR A 1 175 ? 194.557 119.344 178.594 1.00 155.09 ? 190  THR A HB   1 
ATOM   2784 H HG1  . THR A 1 175 ? 192.716 118.046 178.638 1.00 155.35 ? 190  THR A HG1  1 
ATOM   2785 H HG21 . THR A 1 175 ? 194.245 117.733 180.405 1.00 154.35 ? 190  THR A HG21 1 
ATOM   2786 H HG22 . THR A 1 175 ? 195.013 119.204 181.021 1.00 153.88 ? 190  THR A HG22 1 
ATOM   2787 H HG23 . THR A 1 175 ? 193.288 118.912 181.331 1.00 154.57 ? 190  THR A HG23 1 
ATOM   2788 N N    . TYR A 1 176 ? 194.713 122.060 177.632 1.00 141.75 ? 191  TYR A N    1 
ATOM   2789 C CA   . TYR A 1 176 ? 194.837 122.636 176.296 1.00 135.45 ? 191  TYR A CA   1 
ATOM   2790 C C    . TYR A 1 176 ? 195.991 121.968 175.551 1.00 140.27 ? 191  TYR A C    1 
ATOM   2791 O O    . TYR A 1 176 ? 196.966 121.527 176.157 1.00 146.54 ? 191  TYR A O    1 
ATOM   2792 C CB   . TYR A 1 176 ? 195.009 124.157 176.387 1.00 130.77 ? 191  TYR A CB   1 
ATOM   2793 C CG   . TYR A 1 176 ? 196.350 124.613 176.919 1.00 135.09 ? 191  TYR A CG   1 
ATOM   2794 C CD1  . TYR A 1 176 ? 196.548 124.763 178.300 1.00 135.09 ? 191  TYR A CD1  1 
ATOM   2795 C CD2  . TYR A 1 176 ? 197.407 124.865 176.028 1.00 143.10 ? 191  TYR A CD2  1 
ATOM   2796 C CE1  . TYR A 1 176 ? 197.800 125.168 178.791 1.00 141.39 ? 191  TYR A CE1  1 
ATOM   2797 C CE2  . TYR A 1 176 ? 198.664 125.259 176.514 1.00 140.77 ? 191  TYR A CE2  1 
ATOM   2798 C CZ   . TYR A 1 176 ? 198.862 125.406 177.899 1.00 142.85 ? 191  TYR A CZ   1 
ATOM   2799 O OH   . TYR A 1 176 ? 200.086 125.727 178.386 1.00 148.10 ? 191  TYR A OH   1 
ATOM   2800 H H    . TYR A 1 176 ? 195.568 121.837 178.119 1.00 142.47 ? 191  TYR A H    1 
ATOM   2801 H HA   . TYR A 1 176 ? 193.925 122.438 175.733 1.00 140.79 ? 191  TYR A HA   1 
ATOM   2802 H HB2  . TYR A 1 176 ? 194.878 124.574 175.388 1.00 140.64 ? 191  TYR A HB2  1 
ATOM   2803 H HB3  . TYR A 1 176 ? 194.217 124.570 177.011 1.00 139.96 ? 191  TYR A HB3  1 
ATOM   2804 H HD1  . TYR A 1 176 ? 195.736 124.559 178.984 1.00 140.98 ? 191  TYR A HD1  1 
ATOM   2805 H HD2  . TYR A 1 176 ? 197.256 124.751 174.965 1.00 142.43 ? 191  TYR A HD2  1 
ATOM   2806 H HE1  . TYR A 1 176 ? 197.957 125.294 179.852 1.00 142.35 ? 191  TYR A HE1  1 
ATOM   2807 H HE2  . TYR A 1 176 ? 199.475 125.443 175.825 1.00 141.20 ? 191  TYR A HE2  1 
ATOM   2808 H HH   . TYR A 1 176 ? 200.707 125.946 177.687 1.00 142.67 ? 191  TYR A HH   1 
ATOM   2809 N N    . ASN A 1 177 ? 195.893 121.851 174.232 1.00 143.03 ? 192  ASN A N    1 
ATOM   2810 C CA   . ASN A 1 177 ? 196.911 121.201 173.419 1.00 144.63 ? 192  ASN A CA   1 
ATOM   2811 C C    . ASN A 1 177 ? 198.190 122.060 173.347 1.00 144.22 ? 192  ASN A C    1 
ATOM   2812 O O    . ASN A 1 177 ? 198.273 122.985 172.535 1.00 148.41 ? 192  ASN A O    1 
ATOM   2813 C CB   . ASN A 1 177 ? 196.303 120.911 172.041 1.00 146.21 ? 192  ASN A CB   1 
ATOM   2814 C CG   . ASN A 1 177 ? 197.284 120.249 171.093 1.00 152.63 ? 192  ASN A CG   1 
ATOM   2815 O OD1  . ASN A 1 177 ? 198.432 119.970 171.431 1.00 154.64 ? 192  ASN A OD1  1 
ATOM   2816 N ND2  . ASN A 1 177 ? 196.819 120.047 169.877 1.00 152.73 ? 192  ASN A ND2  1 
ATOM   2817 H H    . ASN A 1 177 ? 195.054 122.182 173.779 1.00 147.78 ? 192  ASN A H    1 
ATOM   2818 H HA   . ASN A 1 177 ? 197.172 120.247 173.877 1.00 148.25 ? 192  ASN A HA   1 
ATOM   2819 H HB2  . ASN A 1 177 ? 195.446 120.249 172.163 1.00 148.23 ? 192  ASN A HB2  1 
ATOM   2820 H HB3  . ASN A 1 177 ? 195.951 121.842 171.597 1.00 147.85 ? 192  ASN A HB3  1 
ATOM   2821 H HD21 . ASN A 1 177 ? 195.835 120.201 169.708 1.00 148.20 ? 192  ASN A HD21 1 
ATOM   2822 N N    . VAL A 1 178 ? 199.235 121.662 174.085 1.00 142.16 ? 193  VAL A N    1 
ATOM   2823 C CA   . VAL A 1 178 ? 200.549 122.337 174.128 1.00 145.95 ? 193  VAL A CA   1 
ATOM   2824 C C    . VAL A 1 178 ? 201.221 122.496 172.769 1.00 151.92 ? 193  VAL A C    1 
ATOM   2825 O O    . VAL A 1 178 ? 202.109 123.333 172.642 1.00 159.53 ? 193  VAL A O    1 
ATOM   2826 C CB   . VAL A 1 178 ? 201.542 121.631 175.068 1.00 147.21 ? 193  VAL A CB   1 
ATOM   2827 C CG1  . VAL A 1 178 ? 201.039 121.681 176.503 1.00 150.44 ? 193  VAL A CG1  1 
ATOM   2828 C CG2  . VAL A 1 178 ? 201.819 120.178 174.681 1.00 146.75 ? 193  VAL A CG2  1 
ATOM   2829 H H    . VAL A 1 178 ? 199.081 120.900 174.729 1.00 148.75 ? 193  VAL A H    1 
ATOM   2830 H HA   . VAL A 1 178 ? 200.390 123.346 174.510 1.00 148.72 ? 193  VAL A HA   1 
ATOM   2831 H HB   . VAL A 1 178 ? 202.488 122.173 175.042 1.00 149.23 ? 193  VAL A HB   1 
ATOM   2832 H HG11 . VAL A 1 178 ? 200.831 122.716 176.778 1.00 149.64 ? 193  VAL A HG11 1 
ATOM   2833 H HG12 . VAL A 1 178 ? 200.134 121.084 176.607 1.00 149.55 ? 193  VAL A HG12 1 
ATOM   2834 H HG13 . VAL A 1 178 ? 201.804 121.286 177.171 1.00 149.57 ? 193  VAL A HG13 1 
ATOM   2835 H HG21 . VAL A 1 178 ? 202.246 120.128 173.680 1.00 148.99 ? 193  VAL A HG21 1 
ATOM   2836 H HG22 . VAL A 1 178 ? 202.540 119.750 175.378 1.00 149.22 ? 193  VAL A HG22 1 
ATOM   2837 H HG23 . VAL A 1 178 ? 200.904 119.587 174.717 1.00 149.05 ? 193  VAL A HG23 1 
ATOM   2838 N N    . SER A 1 179 ? 200.826 121.735 171.748 1.00 155.13 ? 194  SER A N    1 
ATOM   2839 C CA   . SER A 1 179 ? 201.429 121.841 170.418 1.00 154.57 ? 194  SER A CA   1 
ATOM   2840 C C    . SER A 1 179 ? 200.883 122.995 169.579 1.00 154.60 ? 194  SER A C    1 
ATOM   2841 O O    . SER A 1 179 ? 201.555 123.412 168.640 1.00 156.90 ? 194  SER A O    1 
ATOM   2842 C CB   . SER A 1 179 ? 201.242 120.540 169.641 1.00 159.69 ? 194  SER A CB   1 
ATOM   2843 O OG   . SER A 1 179 ? 201.864 119.467 170.320 1.00 164.28 ? 194  SER A OG   1 
ATOM   2844 H H    . SER A 1 179 ? 200.066 121.086 171.892 1.00 155.75 ? 194  SER A H    1 
ATOM   2845 H HA   . SER A 1 179 ? 202.501 122.003 170.528 1.00 155.50 ? 194  SER A HA   1 
ATOM   2846 H HB2  . SER A 1 179 ? 200.179 120.335 169.511 1.00 156.75 ? 194  SER A HB2  1 
ATOM   2847 H HB3  . SER A 1 179 ? 201.700 120.643 168.657 1.00 156.81 ? 194  SER A HB3  1 
ATOM   2848 H HG   . SER A 1 179 ? 201.303 119.201 171.053 1.00 157.02 ? 194  SER A HG   1 
ATOM   2849 N N    . THR A 1 180 ? 199.686 123.510 169.864 1.00 150.58 ? 195  THR A N    1 
ATOM   2850 C CA   . THR A 1 180 ? 199.047 124.542 169.019 1.00 149.62 ? 195  THR A CA   1 
ATOM   2851 C C    . THR A 1 180 ? 199.754 125.883 169.131 1.00 145.07 ? 195  THR A C    1 
ATOM   2852 O O    . THR A 1 180 ? 200.318 126.197 170.171 1.00 148.92 ? 195  THR A O    1 
ATOM   2853 C CB   . THR A 1 180 ? 197.564 124.744 169.336 1.00 149.91 ? 195  THR A CB   1 
ATOM   2854 O OG1  . THR A 1 180 ? 197.404 125.245 170.637 1.00 147.72 ? 195  THR A OG1  1 
ATOM   2855 C CG2  . THR A 1 180 ? 196.792 123.438 169.186 1.00 151.75 ? 195  THR A CG2  1 
ATOM   2856 H H    . THR A 1 180 ? 199.201 123.187 170.689 1.00 149.66 ? 195  THR A H    1 
ATOM   2857 H HA   . THR A 1 180 ? 199.114 124.219 167.980 1.00 149.51 ? 195  THR A HA   1 
ATOM   2858 H HB   . THR A 1 180 ? 197.154 125.470 168.634 1.00 148.92 ? 195  THR A HB   1 
ATOM   2859 H HG1  . THR A 1 180 ? 197.616 124.539 171.252 1.00 149.78 ? 195  THR A HG1  1 
ATOM   2860 H HG21 . THR A 1 180 ? 195.745 123.575 169.457 1.00 149.05 ? 195  THR A HG21 1 
ATOM   2861 H HG22 . THR A 1 180 ? 197.228 122.674 169.830 1.00 149.82 ? 195  THR A HG22 1 
ATOM   2862 H HG23 . THR A 1 180 ? 196.844 123.100 168.150 1.00 149.33 ? 195  THR A HG23 1 
ATOM   2863 N N    . ASP A 1 181 ? 199.748 126.688 168.074 1.00 139.13 ? 196  ASP A N    1 
ATOM   2864 C CA   . ASP A 1 181 ? 200.478 127.959 168.068 1.00 141.96 ? 196  ASP A CA   1 
ATOM   2865 C C    . ASP A 1 181 ? 199.711 129.119 168.710 1.00 142.73 ? 196  ASP A C    1 
ATOM   2866 O O    . ASP A 1 181 ? 200.332 130.058 169.205 1.00 147.96 ? 196  ASP A O    1 
ATOM   2867 C CB   . ASP A 1 181 ? 200.865 128.306 166.630 1.00 143.88 ? 196  ASP A CB   1 
ATOM   2868 C CG   . ASP A 1 181 ? 201.826 127.290 166.007 1.00 147.64 ? 196  ASP A CG   1 
ATOM   2869 O OD1  . ASP A 1 181 ? 202.700 126.753 166.726 1.00 149.95 ? 196  ASP A OD1  1 
ATOM   2870 O OD2  . ASP A 1 181 ? 201.716 127.042 164.786 1.00 147.08 ? 196  ASP A OD2  1 
ATOM   2871 H H    . ASP A 1 181 ? 199.291 126.392 167.223 1.00 143.69 ? 196  ASP A H    1 
ATOM   2872 H HA   . ASP A 1 181 ? 201.400 127.847 168.639 1.00 144.15 ? 196  ASP A HA   1 
ATOM   2873 H HB2  . ASP A 1 181 ? 199.959 128.372 166.028 1.00 143.61 ? 196  ASP A HB2  1 
ATOM   2874 H HB3  . ASP A 1 181 ? 201.346 129.284 166.621 1.00 144.18 ? 196  ASP A HB3  1 
ATOM   2875 N N    . TRP A 1 182 ? 198.379 129.069 168.731 1.00 131.18 ? 197  TRP A N    1 
ATOM   2876 C CA   . TRP A 1 182 ? 197.533 130.164 169.204 1.00 126.55 ? 197  TRP A CA   1 
ATOM   2877 C C    . TRP A 1 182 ? 196.372 129.687 170.061 1.00 129.46 ? 197  TRP A C    1 
ATOM   2878 O O    . TRP A 1 182 ? 195.667 128.769 169.665 1.00 135.11 ? 197  TRP A O    1 
ATOM   2879 C CB   . TRP A 1 182 ? 196.982 130.914 167.998 1.00 124.97 ? 197  TRP A CB   1 
ATOM   2880 C CG   . TRP A 1 182 ? 198.026 131.547 167.147 1.00 127.52 ? 197  TRP A CG   1 
ATOM   2881 C CD1  . TRP A 1 182 ? 198.571 131.009 166.037 1.00 132.54 ? 197  TRP A CD1  1 
ATOM   2882 C CD2  . TRP A 1 182 ? 198.709 132.809 167.358 1.00 125.58 ? 197  TRP A CD2  1 
ATOM   2883 N NE1  . TRP A 1 182 ? 199.560 131.842 165.561 1.00 137.08 ? 197  TRP A NE1  1 
ATOM   2884 C CE2  . TRP A 1 182 ? 199.691 132.963 166.342 1.00 131.37 ? 197  TRP A CE2  1 
ATOM   2885 C CE3  . TRP A 1 182 ? 198.594 133.840 168.307 1.00 126.73 ? 197  TRP A CE3  1 
ATOM   2886 C CZ2  . TRP A 1 182 ? 200.534 134.073 166.278 1.00 128.80 ? 197  TRP A CZ2  1 
ATOM   2887 C CZ3  . TRP A 1 182 ? 199.430 134.965 168.248 1.00 136.22 ? 197  TRP A CZ3  1 
ATOM   2888 C CH2  . TRP A 1 182 ? 200.402 135.079 167.244 1.00 132.11 ? 197  TRP A CH2  1 
ATOM   2889 H H    . TRP A 1 182 ? 197.922 128.252 168.350 1.00 132.25 ? 197  TRP A H    1 
ATOM   2890 H HA   . TRP A 1 182 ? 198.130 130.860 169.793 1.00 131.65 ? 197  TRP A HA   1 
ATOM   2891 H HB2  . TRP A 1 182 ? 196.392 130.231 167.385 1.00 131.32 ? 197  TRP A HB2  1 
ATOM   2892 H HB3  . TRP A 1 182 ? 196.315 131.699 168.352 1.00 130.64 ? 197  TRP A HB3  1 
ATOM   2893 H HD1  . TRP A 1 182 ? 198.294 130.055 165.612 1.00 131.46 ? 197  TRP A HD1  1 
ATOM   2894 H HE1  . TRP A 1 182 ? 200.124 131.627 164.751 1.00 132.61 ? 197  TRP A HE1  1 
ATOM   2895 H HE3  . TRP A 1 182 ? 197.856 133.750 169.091 1.00 131.25 ? 197  TRP A HE3  1 
ATOM   2896 H HZ2  . TRP A 1 182 ? 201.280 134.150 165.500 1.00 131.19 ? 197  TRP A HZ2  1 
ATOM   2897 H HZ3  . TRP A 1 182 ? 199.338 135.743 168.992 1.00 132.94 ? 197  TRP A HZ3  1 
ATOM   2898 H HH2  . TRP A 1 182 ? 201.049 135.944 167.212 1.00 131.49 ? 197  TRP A HH2  1 
ATOM   2899 N N    . LEU A 1 183 ? 196.102 130.366 171.172 1.00 126.86 ? 198  LEU A N    1 
ATOM   2900 C CA   . LEU A 1 183 ? 194.877 130.205 171.948 1.00 128.14 ? 198  LEU A CA   1 
ATOM   2901 C C    . LEU A 1 183 ? 194.029 131.466 171.837 1.00 133.03 ? 198  LEU A C    1 
ATOM   2902 O O    . LEU A 1 183 ? 194.553 132.574 171.883 1.00 142.23 ? 198  LEU A O    1 
ATOM   2903 C CB   . LEU A 1 183 ? 195.164 129.906 173.422 1.00 126.03 ? 198  LEU A CB   1 
ATOM   2904 C CG   . LEU A 1 183 ? 195.751 128.516 173.695 1.00 128.21 ? 198  LEU A CG   1 
ATOM   2905 C CD1  . LEU A 1 183 ? 197.271 128.493 173.606 1.00 135.29 ? 198  LEU A CD1  1 
ATOM   2906 C CD2  . LEU A 1 183 ? 195.370 128.075 175.104 1.00 135.70 ? 198  LEU A CD2  1 
ATOM   2907 H H    . LEU A 1 183 ? 196.715 131.129 171.421 1.00 132.83 ? 198  LEU A H    1 
ATOM   2908 H HA   . LEU A 1 183 ? 194.290 129.378 171.547 1.00 133.26 ? 198  LEU A HA   1 
ATOM   2909 H HB2  . LEU A 1 183 ? 195.816 130.672 173.843 1.00 132.87 ? 198  LEU A HB2  1 
ATOM   2910 H HB3  . LEU A 1 183 ? 194.210 129.973 173.944 1.00 132.77 ? 198  LEU A HB3  1 
ATOM   2911 H HG   . LEU A 1 183 ? 195.337 127.797 172.989 1.00 132.53 ? 198  LEU A HG   1 
ATOM   2912 H HD11 . LEU A 1 183 ? 197.586 128.734 172.591 1.00 133.84 ? 198  LEU A HD11 1 
ATOM   2913 H HD12 . LEU A 1 183 ? 197.636 127.496 173.853 1.00 134.54 ? 198  LEU A HD12 1 
ATOM   2914 H HD13 . LEU A 1 183 ? 197.699 129.213 174.303 1.00 134.13 ? 198  LEU A HD13 1 
ATOM   2915 H HD21 . LEU A 1 183 ? 195.800 127.097 175.315 1.00 134.21 ? 198  LEU A HD21 1 
ATOM   2916 H HD22 . LEU A 1 183 ? 195.742 128.795 175.833 1.00 134.02 ? 198  LEU A HD22 1 
ATOM   2917 H HD23 . LEU A 1 183 ? 194.285 128.002 175.189 1.00 133.75 ? 198  LEU A HD23 1 
ATOM   2918 N N    . TYR A 1 184 ? 192.719 131.309 171.725 1.00 123.10 ? 199  TYR A N    1 
ATOM   2919 C CA   . TYR A 1 184 ? 191.771 132.413 171.671 1.00 118.74 ? 199  TYR A CA   1 
ATOM   2920 C C    . TYR A 1 184 ? 190.849 132.374 172.877 1.00 122.95 ? 199  TYR A C    1 
ATOM   2921 O O    . TYR A 1 184 ? 190.407 131.295 173.250 1.00 134.97 ? 199  TYR A O    1 
ATOM   2922 C CB   . TYR A 1 184 ? 190.963 132.336 170.381 1.00 124.20 ? 199  TYR A CB   1 
ATOM   2923 C CG   . TYR A 1 184 ? 191.812 132.443 169.141 1.00 123.13 ? 199  TYR A CG   1 
ATOM   2924 C CD1  . TYR A 1 184 ? 192.228 133.704 168.690 1.00 128.77 ? 199  TYR A CD1  1 
ATOM   2925 C CD2  . TYR A 1 184 ? 192.223 131.283 168.469 1.00 126.50 ? 199  TYR A CD2  1 
ATOM   2926 C CE1  . TYR A 1 184 ? 193.045 133.806 167.553 1.00 133.15 ? 199  TYR A CE1  1 
ATOM   2927 C CE2  . TYR A 1 184 ? 193.061 131.378 167.347 1.00 127.83 ? 199  TYR A CE2  1 
ATOM   2928 C CZ   . TYR A 1 184 ? 193.477 132.643 166.894 1.00 132.28 ? 199  TYR A CZ   1 
ATOM   2929 O OH   . TYR A 1 184 ? 194.307 132.744 165.828 1.00 135.80 ? 199  TYR A OH   1 
ATOM   2930 H H    . TYR A 1 184 ? 192.350 130.368 171.710 1.00 129.30 ? 199  TYR A H    1 
ATOM   2931 H HA   . TYR A 1 184 ? 192.308 133.362 171.672 1.00 128.83 ? 199  TYR A HA   1 
ATOM   2932 H HB2  . TYR A 1 184 ? 190.416 131.393 170.358 1.00 129.28 ? 199  TYR A HB2  1 
ATOM   2933 H HB3  . TYR A 1 184 ? 190.231 133.144 170.375 1.00 129.43 ? 199  TYR A HB3  1 
ATOM   2934 H HD1  . TYR A 1 184 ? 191.930 134.594 169.225 1.00 129.56 ? 199  TYR A HD1  1 
ATOM   2935 H HD2  . TYR A 1 184 ? 191.909 130.312 168.823 1.00 129.90 ? 199  TYR A HD2  1 
ATOM   2936 H HE1  . TYR A 1 184 ? 193.356 134.774 167.188 1.00 129.88 ? 199  TYR A HE1  1 
ATOM   2937 H HE2  . TYR A 1 184 ? 193.388 130.481 166.844 1.00 129.39 ? 199  TYR A HE2  1 
ATOM   2938 H HH   . TYR A 1 184 ? 194.555 131.878 165.495 1.00 130.27 ? 199  TYR A HH   1 
ATOM   2939 N N    . PHE A 1 185 ? 190.521 133.522 173.466 1.00 113.28 ? 200  PHE A N    1 
ATOM   2940 C CA   . PHE A 1 185 ? 189.599 133.615 174.597 1.00 112.18 ? 200  PHE A CA   1 
ATOM   2941 C C    . PHE A 1 185 ? 188.596 134.747 174.423 1.00 116.90 ? 200  PHE A C    1 
ATOM   2942 O O    . PHE A 1 185 ? 188.993 135.839 174.043 1.00 130.03 ? 200  PHE A O    1 
ATOM   2943 C CB   . PHE A 1 185 ? 190.359 133.869 175.896 1.00 117.62 ? 200  PHE A CB   1 
ATOM   2944 C CG   . PHE A 1 185 ? 191.347 132.808 176.317 1.00 124.98 ? 200  PHE A CG   1 
ATOM   2945 C CD1  . PHE A 1 185 ? 190.921 131.763 177.146 1.00 124.71 ? 200  PHE A CD1  1 
ATOM   2946 C CD2  . PHE A 1 185 ? 192.693 132.886 175.930 1.00 121.93 ? 200  PHE A CD2  1 
ATOM   2947 C CE1  . PHE A 1 185 ? 191.831 130.787 177.568 1.00 123.21 ? 200  PHE A CE1  1 
ATOM   2948 C CE2  . PHE A 1 185 ? 193.608 131.915 176.363 1.00 122.21 ? 200  PHE A CE2  1 
ATOM   2949 C CZ   . PHE A 1 185 ? 193.176 130.862 177.180 1.00 125.68 ? 200  PHE A CZ   1 
ATOM   2950 H H    . PHE A 1 185 ? 190.910 134.378 173.096 1.00 124.33 ? 200  PHE A H    1 
ATOM   2951 H HA   . PHE A 1 185 ? 189.049 132.679 174.697 1.00 123.28 ? 200  PHE A HA   1 
ATOM   2952 H HB2  . PHE A 1 185 ? 190.880 134.824 175.826 1.00 122.50 ? 200  PHE A HB2  1 
ATOM   2953 H HB3  . PHE A 1 185 ? 189.625 133.975 176.695 1.00 123.89 ? 200  PHE A HB3  1 
ATOM   2954 H HD1  . PHE A 1 185 ? 189.887 131.706 177.455 1.00 124.47 ? 200  PHE A HD1  1 
ATOM   2955 H HD2  . PHE A 1 185 ? 193.028 133.694 175.295 1.00 123.53 ? 200  PHE A HD2  1 
ATOM   2956 H HE1  . PHE A 1 185 ? 191.488 129.970 178.185 1.00 123.92 ? 200  PHE A HE1  1 
ATOM   2957 H HE2  . PHE A 1 185 ? 194.645 131.972 176.063 1.00 123.79 ? 200  PHE A HE2  1 
ATOM   2958 H HZ   . PHE A 1 185 ? 193.877 130.110 177.508 1.00 124.95 ? 200  PHE A HZ   1 
ATOM   2959 N N    . HIS A 1 186 ? 187.340 134.548 174.810 1.00 115.21 ? 201  HIS A N    1 
ATOM   2960 C CA   . HIS A 1 186 ? 186.415 135.638 175.118 1.00 116.03 ? 201  HIS A CA   1 
ATOM   2961 C C    . HIS A 1 186 ? 186.182 135.657 176.614 1.00 121.77 ? 201  HIS A C    1 
ATOM   2962 O O    . HIS A 1 186 ? 185.745 134.653 177.164 1.00 134.78 ? 201  HIS A O    1 
ATOM   2963 C CB   . HIS A 1 186 ? 185.058 135.469 174.431 1.00 116.31 ? 201  HIS A CB   1 
ATOM   2964 C CG   . HIS A 1 186 ? 185.091 135.487 172.935 1.00 121.72 ? 201  HIS A CG   1 
ATOM   2965 N ND1  . HIS A 1 186 ? 185.703 134.531 172.130 1.00 130.84 ? 201  HIS A ND1  1 
ATOM   2966 C CD2  . HIS A 1 186 ? 184.473 136.406 172.146 1.00 124.36 ? 201  HIS A CD2  1 
ATOM   2967 C CE1  . HIS A 1 186 ? 185.442 134.901 170.869 1.00 137.45 ? 201  HIS A CE1  1 
ATOM   2968 N NE2  . HIS A 1 186 ? 184.719 136.027 170.851 1.00 133.43 ? 201  HIS A NE2  1 
ATOM   2969 H H    . HIS A 1 186 ? 187.095 133.625 175.139 1.00 126.21 ? 201  HIS A H    1 
ATOM   2970 H HA   . HIS A 1 186 ? 186.835 136.597 174.816 1.00 125.57 ? 201  HIS A HA   1 
ATOM   2971 H HB2  . HIS A 1 186 ? 184.591 134.540 174.760 1.00 125.33 ? 201  HIS A HB2  1 
ATOM   2972 H HB3  . HIS A 1 186 ? 184.410 136.280 174.761 1.00 125.69 ? 201  HIS A HB3  1 
ATOM   2973 H HD2  . HIS A 1 186 ? 183.882 137.246 172.478 1.00 126.11 ? 201  HIS A HD2  1 
ATOM   2974 H HE1  . HIS A 1 186 ? 185.775 134.370 169.989 1.00 128.59 ? 201  HIS A HE1  1 
ATOM   2975 H HE2  . HIS A 1 186 ? 184.405 136.496 170.014 1.00 127.95 ? 201  HIS A HE2  1 
ATOM   2976 N N    . PHE A 1 187 ? 186.415 136.788 177.262 1.00 114.80 ? 202  PHE A N    1 
ATOM   2977 C CA   . PHE A 1 187 ? 186.002 137.025 178.636 1.00 117.04 ? 202  PHE A CA   1 
ATOM   2978 C C    . PHE A 1 187 ? 185.007 138.174 178.620 1.00 123.44 ? 202  PHE A C    1 
ATOM   2979 O O    . PHE A 1 187 ? 185.357 139.263 178.178 1.00 134.23 ? 202  PHE A O    1 
ATOM   2980 C CB   . PHE A 1 187 ? 187.228 137.361 179.490 1.00 119.42 ? 202  PHE A CB   1 
ATOM   2981 C CG   . PHE A 1 187 ? 188.305 136.299 179.502 1.00 118.25 ? 202  PHE A CG   1 
ATOM   2982 C CD1  . PHE A 1 187 ? 188.035 135.029 180.029 1.00 117.53 ? 202  PHE A CD1  1 
ATOM   2983 C CD2  . PHE A 1 187 ? 189.580 136.586 178.994 1.00 120.51 ? 202  PHE A CD2  1 
ATOM   2984 C CE1  . PHE A 1 187 ? 189.043 134.054 180.068 1.00 124.13 ? 202  PHE A CE1  1 
ATOM   2985 C CE2  . PHE A 1 187 ? 190.587 135.611 179.028 1.00 126.49 ? 202  PHE A CE2  1 
ATOM   2986 C CZ   . PHE A 1 187 ? 190.320 134.346 179.569 1.00 127.38 ? 202  PHE A CZ   1 
ATOM   2987 H H    . PHE A 1 187 ? 186.776 137.578 176.747 1.00 123.39 ? 202  PHE A H    1 
ATOM   2988 H HA   . PHE A 1 187 ? 185.515 136.145 179.054 1.00 123.14 ? 202  PHE A HA   1 
ATOM   2989 H HB2  . PHE A 1 187 ? 187.659 138.296 179.135 1.00 124.07 ? 202  PHE A HB2  1 
ATOM   2990 H HB3  . PHE A 1 187 ? 186.897 137.527 180.516 1.00 123.73 ? 202  PHE A HB3  1 
ATOM   2991 H HD1  . PHE A 1 187 ? 187.052 134.800 180.411 1.00 122.52 ? 202  PHE A HD1  1 
ATOM   2992 H HD2  . PHE A 1 187 ? 189.796 137.561 178.581 1.00 123.39 ? 202  PHE A HD2  1 
ATOM   2993 H HE1  . PHE A 1 187 ? 188.836 133.078 180.481 1.00 124.67 ? 202  PHE A HE1  1 
ATOM   2994 H HE2  . PHE A 1 187 ? 191.569 135.835 178.639 1.00 124.45 ? 202  PHE A HE2  1 
ATOM   2995 H HZ   . PHE A 1 187 ? 191.095 133.594 179.595 1.00 124.42 ? 202  PHE A HZ   1 
ATOM   2996 N N    . TYR A 1 188 ? 183.778 137.982 179.083 1.00 124.96 ? 203  TYR A N    1 
ATOM   2997 C CA   . TYR A 1 188 ? 182.797 139.064 179.143 1.00 127.55 ? 203  TYR A CA   1 
ATOM   2998 C C    . TYR A 1 188 ? 181.887 138.938 180.353 1.00 134.03 ? 203  TYR A C    1 
ATOM   2999 O O    . TYR A 1 188 ? 181.826 137.888 180.985 1.00 140.19 ? 203  TYR A O    1 
ATOM   3000 C CB   . TYR A 1 188 ? 182.024 139.180 177.825 1.00 129.96 ? 203  TYR A CB   1 
ATOM   3001 C CG   . TYR A 1 188 ? 181.015 138.099 177.530 1.00 129.19 ? 203  TYR A CG   1 
ATOM   3002 C CD1  . TYR A 1 188 ? 179.728 138.175 178.083 1.00 129.88 ? 203  TYR A CD1  1 
ATOM   3003 C CD2  . TYR A 1 188 ? 181.339 137.061 176.642 1.00 133.13 ? 203  TYR A CD2  1 
ATOM   3004 C CE1  . TYR A 1 188 ? 178.769 137.198 177.776 1.00 134.11 ? 203  TYR A CE1  1 
ATOM   3005 C CE2  . TYR A 1 188 ? 180.376 136.094 176.315 1.00 134.80 ? 203  TYR A CE2  1 
ATOM   3006 C CZ   . TYR A 1 188 ? 179.092 136.157 176.887 1.00 137.22 ? 203  TYR A CZ   1 
ATOM   3007 O OH   . TYR A 1 188 ? 178.161 135.226 176.570 1.00 142.50 ? 203  TYR A OH   1 
ATOM   3008 H H    . TYR A 1 188 ? 183.520 137.078 179.451 1.00 132.85 ? 203  TYR A H    1 
ATOM   3009 H HA   . TYR A 1 188 ? 183.334 140.003 179.281 1.00 133.38 ? 203  TYR A HA   1 
ATOM   3010 H HB2  . TYR A 1 188 ? 181.485 140.128 177.819 1.00 133.31 ? 203  TYR A HB2  1 
ATOM   3011 H HB3  . TYR A 1 188 ? 182.738 139.228 177.003 1.00 133.83 ? 203  TYR A HB3  1 
ATOM   3012 H HD1  . TYR A 1 188 ? 179.463 138.995 178.734 1.00 133.24 ? 203  TYR A HD1  1 
ATOM   3013 H HD2  . TYR A 1 188 ? 182.321 137.015 176.197 1.00 133.93 ? 203  TYR A HD2  1 
ATOM   3014 H HE1  . TYR A 1 188 ? 177.780 137.256 178.207 1.00 134.03 ? 203  TYR A HE1  1 
ATOM   3015 H HE2  . TYR A 1 188 ? 180.611 135.302 175.618 1.00 134.15 ? 203  TYR A HE2  1 
ATOM   3016 H HH   . TYR A 1 188 ? 177.372 135.316 177.109 1.00 134.97 ? 203  TYR A HH   1 
ATOM   3017 N N    . GLN A 1 189 ? 181.191 140.012 180.704 1.00 141.89 ? 204  GLN A N    1 
ATOM   3018 C CA   . GLN A 1 189 ? 180.249 140.021 181.818 1.00 138.92 ? 204  GLN A CA   1 
ATOM   3019 C C    . GLN A 1 189 ? 178.876 140.521 181.387 1.00 137.55 ? 204  GLN A C    1 
ATOM   3020 O O    . GLN A 1 189 ? 178.756 141.475 180.626 1.00 137.40 ? 204  GLN A O    1 
ATOM   3021 C CB   . GLN A 1 189 ? 180.812 140.816 183.001 1.00 136.73 ? 204  GLN A CB   1 
ATOM   3022 C CG   . GLN A 1 189 ? 180.989 142.317 182.717 1.00 137.65 ? 204  GLN A CG   1 
ATOM   3023 C CD   . GLN A 1 189 ? 181.558 143.079 183.904 1.00 139.30 ? 204  GLN A CD   1 
ATOM   3024 O OE1  . GLN A 1 189 ? 181.494 142.659 185.049 1.00 142.64 ? 204  GLN A OE1  1 
ATOM   3025 N NE2  . GLN A 1 189 ? 182.131 144.237 183.681 1.00 141.27 ? 204  GLN A NE2  1 
ATOM   3026 H H    . GLN A 1 189 ? 181.285 140.852 180.150 1.00 139.63 ? 204  GLN A H    1 
ATOM   3027 H HA   . GLN A 1 189 ? 180.114 138.996 182.163 1.00 139.05 ? 204  GLN A HA   1 
ATOM   3028 H HB2  . GLN A 1 189 ? 180.130 140.696 183.844 1.00 139.39 ? 204  GLN A HB2  1 
ATOM   3029 H HB3  . GLN A 1 189 ? 181.773 140.390 183.285 1.00 138.77 ? 204  GLN A HB3  1 
ATOM   3030 H HG2  . GLN A 1 189 ? 181.656 142.446 181.864 1.00 139.63 ? 204  GLN A HG2  1 
ATOM   3031 H HG3  . GLN A 1 189 ? 180.027 142.767 182.472 1.00 139.30 ? 204  GLN A HG3  1 
ATOM   3032 H HE21 . GLN A 1 189 ? 182.218 144.599 182.741 1.00 140.09 ? 204  GLN A HE21 1 
ATOM   3033 H HE22 . GLN A 1 189 ? 182.577 144.712 184.453 1.00 140.17 ? 204  GLN A HE22 1 
ATOM   3034 N N    . GLU A 1 190 ? 177.826 139.898 181.902 1.00 145.44 ? 205  GLU A N    1 
ATOM   3035 C CA   . GLU A 1 190 ? 176.450 140.350 181.719 1.00 147.37 ? 205  GLU A CA   1 
ATOM   3036 C C    . GLU A 1 190 ? 175.680 140.139 183.026 1.00 146.26 ? 205  GLU A C    1 
ATOM   3037 O O    . GLU A 1 190 ? 175.785 139.075 183.632 1.00 149.22 ? 205  GLU A O    1 
ATOM   3038 C CB   . GLU A 1 190 ? 175.842 139.622 180.507 1.00 150.30 ? 205  GLU A CB   1 
ATOM   3039 C CG   . GLU A 1 190 ? 174.390 140.023 180.241 1.00 154.12 ? 205  GLU A CG   1 
ATOM   3040 C CD   . GLU A 1 190 ? 173.835 139.407 178.948 1.00 157.57 ? 205  GLU A CD   1 
ATOM   3041 O OE1  . GLU A 1 190 ? 174.281 139.816 177.855 1.00 160.41 ? 205  GLU A OE1  1 
ATOM   3042 O OE2  . GLU A 1 190 ? 172.896 138.579 179.019 1.00 161.11 ? 205  GLU A OE2  1 
ATOM   3043 H H    . GLU A 1 190 ? 177.988 139.126 182.532 1.00 149.71 ? 205  GLU A H    1 
ATOM   3044 H HA   . GLU A 1 190 ? 176.444 141.418 181.501 1.00 149.64 ? 205  GLU A HA   1 
ATOM   3045 H HB2  . GLU A 1 190 ? 176.439 139.854 179.626 1.00 149.75 ? 205  GLU A HB2  1 
ATOM   3046 H HB3  . GLU A 1 190 ? 175.879 138.544 180.672 1.00 150.36 ? 205  GLU A HB3  1 
ATOM   3047 H HG2  . GLU A 1 190 ? 173.782 139.711 181.091 1.00 151.27 ? 205  GLU A HG2  1 
ATOM   3048 H HG3  . GLU A 1 190 ? 174.334 141.110 180.175 1.00 150.50 ? 205  GLU A HG3  1 
ATOM   3049 N N    . ARG A 1 191 ? 174.936 141.148 183.491 1.00 139.96 ? 206  ARG A N    1 
ATOM   3050 C CA   . ARG A 1 191 ? 174.121 141.103 184.723 1.00 146.49 ? 206  ARG A CA   1 
ATOM   3051 C C    . ARG A 1 191 ? 174.840 140.470 185.923 1.00 149.50 ? 206  ARG A C    1 
ATOM   3052 O O    . ARG A 1 191 ? 174.332 139.548 186.559 1.00 150.89 ? 206  ARG A O    1 
ATOM   3053 C CB   . ARG A 1 191 ? 172.759 140.448 184.434 1.00 151.08 ? 206  ARG A CB   1 
ATOM   3054 C CG   . ARG A 1 191 ? 171.913 141.267 183.449 1.00 153.60 ? 206  ARG A CG   1 
ATOM   3055 C CD   . ARG A 1 191 ? 170.504 140.680 183.279 1.00 151.13 ? 206  ARG A CD   1 
ATOM   3056 N NE   . ARG A 1 191 ? 170.544 139.313 182.731 1.00 155.55 ? 206  ARG A NE   1 
ATOM   3057 C CZ   . ARG A 1 191 ? 170.878 138.991 181.497 1.00 153.96 ? 206  ARG A CZ   1 
ATOM   3058 N NH1  . ARG A 1 191 ? 171.202 137.774 181.186 1.00 152.88 ? 206  ARG A NH1  1 
ATOM   3059 N NH2  . ARG A 1 191 ? 170.943 139.867 180.541 1.00 153.43 ? 206  ARG A NH2  1 
ATOM   3060 H H    . ARG A 1 191 ? 174.914 142.001 182.950 1.00 148.68 ? 206  ARG A H    1 
ATOM   3061 H HA   . ARG A 1 191 ? 173.924 142.129 185.033 1.00 149.95 ? 206  ARG A HA   1 
ATOM   3062 H HB2  . ARG A 1 191 ? 172.918 139.443 184.041 1.00 150.30 ? 206  ARG A HB2  1 
ATOM   3063 H HB3  . ARG A 1 191 ? 172.199 140.369 185.365 1.00 150.07 ? 206  ARG A HB3  1 
ATOM   3064 H HG2  . ARG A 1 191 ? 171.815 142.284 183.831 1.00 150.86 ? 206  ARG A HG2  1 
ATOM   3065 H HG3  . ARG A 1 191 ? 172.412 141.313 182.481 1.00 150.40 ? 206  ARG A HG3  1 
ATOM   3066 H HD2  . ARG A 1 191 ? 170.012 140.663 184.251 1.00 150.45 ? 206  ARG A HD2  1 
ATOM   3067 H HD3  . ARG A 1 191 ? 169.921 141.331 182.626 1.00 149.41 ? 206  ARG A HD3  1 
ATOM   3068 H HE   . ARG A 1 191 ? 170.462 138.549 183.387 1.00 151.21 ? 206  ARG A HE   1 
ATOM   3069 H HH11 . ARG A 1 191 ? 171.178 137.038 181.877 1.00 150.08 ? 206  ARG A HH11 1 
ATOM   3070 H HH12 . ARG A 1 191 ? 171.638 137.628 180.286 1.00 150.88 ? 206  ARG A HH12 1 
ATOM   3071 H HH21 . ARG A 1 191 ? 170.665 140.823 180.710 1.00 149.80 ? 206  ARG A HH21 1 
ATOM   3072 H HH22 . ARG A 1 191 ? 171.347 139.566 179.666 1.00 151.46 ? 206  ARG A HH22 1 
ATOM   3073 N N    . GLY A 1 192 ? 176.057 140.922 186.217 1.00 150.63 ? 207  GLY A N    1 
ATOM   3074 C CA   . GLY A 1 192 ? 176.842 140.450 187.368 1.00 151.05 ? 207  GLY A CA   1 
ATOM   3075 C C    . GLY A 1 192 ? 177.360 139.011 187.265 1.00 149.42 ? 207  GLY A C    1 
ATOM   3076 O O    . GLY A 1 192 ? 177.838 138.457 188.256 1.00 149.31 ? 207  GLY A O    1 
ATOM   3077 H H    . GLY A 1 192 ? 176.426 141.675 185.655 1.00 148.59 ? 207  GLY A H    1 
ATOM   3078 H HA2  . GLY A 1 192 ? 177.707 141.103 187.487 1.00 148.39 ? 207  GLY A HA2  1 
ATOM   3079 H HA3  . GLY A 1 192 ? 176.235 140.527 188.270 1.00 149.12 ? 207  GLY A HA3  1 
ATOM   3080 N N    . THR A 1 193 ? 177.266 138.391 186.093 1.00 138.13 ? 208  THR A N    1 
ATOM   3081 C CA   . THR A 1 193 ? 177.816 137.064 185.800 1.00 137.60 ? 208  THR A CA   1 
ATOM   3082 C C    . THR A 1 193 ? 178.954 137.188 184.797 1.00 137.84 ? 208  THR A C    1 
ATOM   3083 O O    . THR A 1 193 ? 178.798 137.834 183.766 1.00 137.88 ? 208  THR A O    1 
ATOM   3084 C CB   . THR A 1 193 ? 176.720 136.143 185.261 1.00 137.77 ? 208  THR A CB   1 
ATOM   3085 O OG1  . THR A 1 193 ? 175.676 136.058 186.200 1.00 137.52 ? 208  THR A OG1  1 
ATOM   3086 C CG2  . THR A 1 193 ? 177.201 134.719 185.010 1.00 134.68 ? 208  THR A CG2  1 
ATOM   3087 H H    . THR A 1 193 ? 176.837 138.884 185.323 1.00 138.80 ? 208  THR A H    1 
ATOM   3088 H HA   . THR A 1 193 ? 178.212 136.616 186.711 1.00 137.92 ? 208  THR A HA   1 
ATOM   3089 H HB   . THR A 1 193 ? 176.325 136.550 184.330 1.00 138.25 ? 208  THR A HB   1 
ATOM   3090 H HG1  . THR A 1 193 ? 175.292 136.935 186.264 1.00 138.29 ? 208  THR A HG1  1 
ATOM   3091 H HG21 . THR A 1 193 ? 176.364 134.108 184.673 1.00 137.81 ? 208  THR A HG21 1 
ATOM   3092 H HG22 . THR A 1 193 ? 177.966 134.713 184.233 1.00 137.56 ? 208  THR A HG22 1 
ATOM   3093 H HG23 . THR A 1 193 ? 177.607 134.294 185.928 1.00 137.65 ? 208  THR A HG23 1 
ATOM   3094 N N    . PHE A 1 194 ? 180.097 136.581 185.089 1.00 133.53 ? 209  PHE A N    1 
ATOM   3095 C CA   . PHE A 1 194 ? 181.238 136.472 184.187 1.00 127.81 ? 209  PHE A CA   1 
ATOM   3096 C C    . PHE A 1 194 ? 181.103 135.234 183.300 1.00 132.21 ? 209  PHE A C    1 
ATOM   3097 O O    . PHE A 1 194 ? 180.651 134.197 183.774 1.00 139.63 ? 209  PHE A O    1 
ATOM   3098 C CB   . PHE A 1 194 ? 182.499 136.399 185.046 1.00 130.72 ? 209  PHE A CB   1 
ATOM   3099 C CG   . PHE A 1 194 ? 183.791 136.256 184.282 1.00 130.44 ? 209  PHE A CG   1 
ATOM   3100 C CD1  . PHE A 1 194 ? 184.413 137.396 183.753 1.00 134.73 ? 209  PHE A CD1  1 
ATOM   3101 C CD2  . PHE A 1 194 ? 184.398 134.999 184.142 1.00 129.94 ? 209  PHE A CD2  1 
ATOM   3102 C CE1  . PHE A 1 194 ? 185.666 137.292 183.139 1.00 134.06 ? 209  PHE A CE1  1 
ATOM   3103 C CE2  . PHE A 1 194 ? 185.642 134.894 183.502 1.00 128.05 ? 209  PHE A CE2  1 
ATOM   3104 C CZ   . PHE A 1 194 ? 186.282 136.041 183.017 1.00 128.72 ? 209  PHE A CZ   1 
ATOM   3105 H H    . PHE A 1 194 ? 180.144 136.045 185.945 1.00 133.71 ? 209  PHE A H    1 
ATOM   3106 H HA   . PHE A 1 194 ? 181.298 137.355 183.551 1.00 132.15 ? 209  PHE A HA   1 
ATOM   3107 H HB2  . PHE A 1 194 ? 182.558 137.305 185.649 1.00 133.49 ? 209  PHE A HB2  1 
ATOM   3108 H HB3  . PHE A 1 194 ? 182.408 135.560 185.736 1.00 132.68 ? 209  PHE A HB3  1 
ATOM   3109 H HD1  . PHE A 1 194 ? 183.936 138.361 183.840 1.00 133.53 ? 209  PHE A HD1  1 
ATOM   3110 H HD2  . PHE A 1 194 ? 183.921 134.116 184.540 1.00 132.45 ? 209  PHE A HD2  1 
ATOM   3111 H HE1  . PHE A 1 194 ? 186.160 138.178 182.767 1.00 133.30 ? 209  PHE A HE1  1 
ATOM   3112 H HE2  . PHE A 1 194 ? 186.118 133.930 183.397 1.00 131.93 ? 209  PHE A HE2  1 
ATOM   3113 H HZ   . PHE A 1 194 ? 187.254 135.960 182.552 1.00 131.98 ? 209  PHE A HZ   1 
ATOM   3114 N N    . TYR A 1 195 ? 181.521 135.314 182.041 1.00 132.64 ? 210  TYR A N    1 
ATOM   3115 C CA   . TYR A 1 195 ? 181.480 134.232 181.063 1.00 129.56 ? 210  TYR A CA   1 
ATOM   3116 C C    . TYR A 1 195 ? 182.839 134.096 180.387 1.00 133.99 ? 210  TYR A C    1 
ATOM   3117 O O    . TYR A 1 195 ? 183.416 135.098 179.968 1.00 145.11 ? 210  TYR A O    1 
ATOM   3118 C CB   . TYR A 1 195 ? 180.429 134.531 179.990 1.00 131.64 ? 210  TYR A CB   1 
ATOM   3119 C CG   . TYR A 1 195 ? 179.006 134.631 180.484 1.00 132.79 ? 210  TYR A CG   1 
ATOM   3120 C CD1  . TYR A 1 195 ? 178.541 135.828 181.053 1.00 136.83 ? 210  TYR A CD1  1 
ATOM   3121 C CD2  . TYR A 1 195 ? 178.135 133.539 180.345 1.00 130.36 ? 210  TYR A CD2  1 
ATOM   3122 C CE1  . TYR A 1 195 ? 177.215 135.933 181.501 1.00 136.74 ? 210  TYR A CE1  1 
ATOM   3123 C CE2  . TYR A 1 195 ? 176.808 133.636 180.797 1.00 135.66 ? 210  TYR A CE2  1 
ATOM   3124 C CZ   . TYR A 1 195 ? 176.346 134.833 181.376 1.00 138.91 ? 210  TYR A CZ   1 
ATOM   3125 O OH   . TYR A 1 195 ? 175.065 134.922 181.808 1.00 143.67 ? 210  TYR A OH   1 
ATOM   3126 H H    . TYR A 1 195 ? 181.867 136.205 181.714 1.00 136.11 ? 210  TYR A H    1 
ATOM   3127 H HA   . TYR A 1 195 ? 181.232 133.288 181.547 1.00 135.59 ? 210  TYR A HA   1 
ATOM   3128 H HB2  . TYR A 1 195 ? 180.687 135.467 179.496 1.00 135.42 ? 210  TYR A HB2  1 
ATOM   3129 H HB3  . TYR A 1 195 ? 180.479 133.746 179.235 1.00 135.08 ? 210  TYR A HB3  1 
ATOM   3130 H HD1  . TYR A 1 195 ? 179.208 136.673 181.144 1.00 136.65 ? 210  TYR A HD1  1 
ATOM   3131 H HD2  . TYR A 1 195 ? 178.481 132.626 179.885 1.00 135.33 ? 210  TYR A HD2  1 
ATOM   3132 H HE1  . TYR A 1 195 ? 176.868 136.852 181.947 1.00 136.65 ? 210  TYR A HE1  1 
ATOM   3133 H HE2  . TYR A 1 195 ? 176.132 132.800 180.695 1.00 136.63 ? 210  TYR A HE2  1 
ATOM   3134 H HH   . TYR A 1 195 ? 174.861 135.802 182.137 1.00 136.64 ? 210  TYR A HH   1 
ATOM   3135 N N    . ALA A 1 196 ? 183.324 132.870 180.220 1.00 130.50 ? 211  ALA A N    1 
ATOM   3136 C CA   . ALA A 1 196 ? 184.570 132.588 179.526 1.00 130.94 ? 211  ALA A CA   1 
ATOM   3137 C C    . ALA A 1 196 ? 184.358 131.576 178.408 1.00 129.22 ? 211  ALA A C    1 
ATOM   3138 O O    . ALA A 1 196 ? 183.826 130.491 178.632 1.00 136.70 ? 211  ALA A O    1 
ATOM   3139 C CB   . ALA A 1 196 ? 185.602 132.077 180.524 1.00 133.08 ? 211  ALA A CB   1 
ATOM   3140 H H    . ALA A 1 196 ? 182.822 132.084 180.607 1.00 133.35 ? 211  ALA A H    1 
ATOM   3141 H HA   . ALA A 1 196 ? 184.966 133.506 179.090 1.00 132.90 ? 211  ALA A HA   1 
ATOM   3142 H HB1  . ALA A 1 196 ? 185.765 132.821 181.303 1.00 133.05 ? 211  ALA A HB1  1 
ATOM   3143 H HB2  . ALA A 1 196 ? 186.543 131.882 180.011 1.00 132.46 ? 211  ALA A HB2  1 
ATOM   3144 H HB3  . ALA A 1 196 ? 185.243 131.153 180.977 1.00 133.71 ? 211  ALA A HB3  1 
ATOM   3145 N N    . TYR A 1 197 ? 184.840 131.894 177.215 1.00 124.84 ? 212  TYR A N    1 
ATOM   3146 C CA   . TYR A 1 197 ? 184.931 130.982 176.085 1.00 125.75 ? 212  TYR A CA   1 
ATOM   3147 C C    . TYR A 1 197 ? 186.388 130.889 175.664 1.00 127.21 ? 212  TYR A C    1 
ATOM   3148 O O    . TYR A 1 197 ? 187.111 131.874 175.761 1.00 138.87 ? 212  TYR A O    1 
ATOM   3149 C CB   . TYR A 1 197 ? 184.123 131.473 174.885 1.00 128.17 ? 212  TYR A CB   1 
ATOM   3150 C CG   . TYR A 1 197 ? 182.621 131.578 175.031 1.00 127.33 ? 212  TYR A CG   1 
ATOM   3151 C CD1  . TYR A 1 197 ? 182.037 132.443 175.972 1.00 126.89 ? 212  TYR A CD1  1 
ATOM   3152 C CD2  . TYR A 1 197 ? 181.801 130.845 174.160 1.00 130.35 ? 212  TYR A CD2  1 
ATOM   3153 C CE1  . TYR A 1 197 ? 180.640 132.513 176.090 1.00 129.48 ? 212  TYR A CE1  1 
ATOM   3154 C CE2  . TYR A 1 197 ? 180.403 130.923 174.263 1.00 131.96 ? 212  TYR A CE2  1 
ATOM   3155 C CZ   . TYR A 1 197 ? 179.822 131.745 175.245 1.00 135.52 ? 212  TYR A CZ   1 
ATOM   3156 O OH   . TYR A 1 197 ? 178.474 131.797 175.378 1.00 141.52 ? 212  TYR A OH   1 
ATOM   3157 H H    . TYR A 1 197 ? 185.281 132.797 177.115 1.00 131.80 ? 212  TYR A H    1 
ATOM   3158 H HA   . TYR A 1 197 ? 184.582 129.989 176.373 1.00 131.62 ? 212  TYR A HA   1 
ATOM   3159 H HB2  . TYR A 1 197 ? 184.512 132.440 174.568 1.00 131.31 ? 212  TYR A HB2  1 
ATOM   3160 H HB3  . TYR A 1 197 ? 184.328 130.782 174.066 1.00 131.33 ? 212  TYR A HB3  1 
ATOM   3161 H HD1  . TYR A 1 197 ? 182.651 133.064 176.605 1.00 131.44 ? 212  TYR A HD1  1 
ATOM   3162 H HD2  . TYR A 1 197 ? 182.241 130.225 173.393 1.00 131.87 ? 212  TYR A HD2  1 
ATOM   3163 H HE1  . TYR A 1 197 ? 180.181 133.159 176.826 1.00 131.28 ? 212  TYR A HE1  1 
ATOM   3164 H HE2  . TYR A 1 197 ? 179.779 130.351 173.593 1.00 131.72 ? 212  TYR A HE2  1 
ATOM   3165 H HH   . TYR A 1 197 ? 178.037 131.244 174.725 1.00 132.59 ? 212  TYR A HH   1 
ATOM   3166 N N    . TYR A 1 198 ? 186.832 129.748 175.158 1.00 129.24 ? 213  TYR A N    1 
ATOM   3167 C CA   . TYR A 1 198 ? 188.169 129.615 174.605 1.00 130.74 ? 213  TYR A CA   1 
ATOM   3168 C C    . TYR A 1 198 ? 188.215 128.700 173.388 1.00 134.81 ? 213  TYR A C    1 
ATOM   3169 O O    . TYR A 1 198 ? 187.269 127.972 173.112 1.00 137.12 ? 213  TYR A O    1 
ATOM   3170 C CB   . TYR A 1 198 ? 189.166 129.211 175.697 1.00 126.83 ? 213  TYR A CB   1 
ATOM   3171 C CG   . TYR A 1 198 ? 189.545 127.752 175.762 1.00 129.68 ? 213  TYR A CG   1 
ATOM   3172 C CD1  . TYR A 1 198 ? 188.554 126.757 175.719 1.00 132.50 ? 213  TYR A CD1  1 
ATOM   3173 C CD2  . TYR A 1 198 ? 190.901 127.393 175.812 1.00 131.60 ? 213  TYR A CD2  1 
ATOM   3174 C CE1  . TYR A 1 198 ? 188.918 125.403 175.708 1.00 134.62 ? 213  TYR A CE1  1 
ATOM   3175 C CE2  . TYR A 1 198 ? 191.269 126.041 175.808 1.00 137.33 ? 213  TYR A CE2  1 
ATOM   3176 C CZ   . TYR A 1 198 ? 190.279 125.044 175.750 1.00 140.44 ? 213  TYR A CZ   1 
ATOM   3177 O OH   . TYR A 1 198 ? 190.636 123.738 175.717 1.00 141.79 ? 213  TYR A OH   1 
ATOM   3178 H H    . TYR A 1 198 ? 186.187 128.978 175.043 1.00 134.38 ? 213  TYR A H    1 
ATOM   3179 H HA   . TYR A 1 198 ? 188.456 130.605 174.249 1.00 134.11 ? 213  TYR A HA   1 
ATOM   3180 H HB2  . TYR A 1 198 ? 190.078 129.774 175.499 1.00 133.13 ? 213  TYR A HB2  1 
ATOM   3181 H HB3  . TYR A 1 198 ? 188.802 129.529 176.674 1.00 133.72 ? 213  TYR A HB3  1 
ATOM   3182 H HD1  . TYR A 1 198 ? 187.510 127.028 175.672 1.00 133.71 ? 213  TYR A HD1  1 
ATOM   3183 H HD2  . TYR A 1 198 ? 191.664 128.156 175.845 1.00 133.07 ? 213  TYR A HD2  1 
ATOM   3184 H HE1  . TYR A 1 198 ? 188.156 124.639 175.661 1.00 133.58 ? 213  TYR A HE1  1 
ATOM   3185 H HE2  . TYR A 1 198 ? 192.311 125.756 175.839 1.00 134.20 ? 213  TYR A HE2  1 
ATOM   3186 H HH   . TYR A 1 198 ? 189.873 123.157 175.726 1.00 134.81 ? 213  TYR A HH   1 
ATOM   3187 N N    . ALA A 1 199 ? 189.305 128.737 172.641 1.00 133.26 ? 214  ALA A N    1 
ATOM   3188 C CA   . ALA A 1 199 ? 189.685 127.670 171.732 1.00 124.99 ? 214  ALA A CA   1 
ATOM   3189 C C    . ALA A 1 199 ? 191.201 127.531 171.724 1.00 128.55 ? 214  ALA A C    1 
ATOM   3190 O O    . ALA A 1 199 ? 191.908 128.530 171.628 1.00 135.36 ? 214  ALA A O    1 
ATOM   3191 C CB   . ALA A 1 199 ? 189.156 127.967 170.328 1.00 126.34 ? 214  ALA A CB   1 
ATOM   3192 H H    . ALA A 1 199 ? 190.004 129.432 172.861 1.00 132.67 ? 214  ALA A H    1 
ATOM   3193 H HA   . ALA A 1 199 ? 189.260 126.727 172.074 1.00 130.80 ? 214  ALA A HA   1 
ATOM   3194 H HB1  . ALA A 1 199 ? 189.655 127.322 169.605 1.00 131.86 ? 214  ALA A HB1  1 
ATOM   3195 H HB2  . ALA A 1 199 ? 189.338 129.007 170.058 1.00 131.89 ? 214  ALA A HB2  1 
ATOM   3196 H HB3  . ALA A 1 199 ? 188.090 127.743 170.291 1.00 131.44 ? 214  ALA A HB3  1 
ATOM   3197 N N    . ASP A 1 200 ? 191.708 126.305 171.780 1.00 138.93 ? 215  ASP A N    1 
ATOM   3198 C CA   . ASP A 1 200 ? 193.116 126.014 171.516 1.00 145.11 ? 215  ASP A CA   1 
ATOM   3199 C C    . ASP A 1 200 ? 193.355 125.588 170.063 1.00 145.56 ? 215  ASP A C    1 
ATOM   3200 O O    . ASP A 1 200 ? 194.466 125.703 169.565 1.00 146.06 ? 215  ASP A O    1 
ATOM   3201 C CB   . ASP A 1 200 ? 193.638 124.962 172.503 1.00 151.48 ? 215  ASP A CB   1 
ATOM   3202 C CG   . ASP A 1 200 ? 192.929 123.606 172.452 1.00 153.92 ? 215  ASP A CG   1 
ATOM   3203 O OD1  . ASP A 1 200 ? 191.837 123.502 171.851 1.00 156.28 ? 215  ASP A OD1  1 
ATOM   3204 O OD2  . ASP A 1 200 ? 193.489 122.641 173.016 1.00 152.01 ? 215  ASP A OD2  1 
ATOM   3205 H H    . ASP A 1 200 ? 191.098 125.512 171.910 1.00 145.64 ? 215  ASP A H    1 
ATOM   3206 H HA   . ASP A 1 200 ? 193.706 126.917 171.673 1.00 145.99 ? 215  ASP A HA   1 
ATOM   3207 H HB2  . ASP A 1 200 ? 194.701 124.816 172.315 1.00 147.77 ? 215  ASP A HB2  1 
ATOM   3208 H HB3  . ASP A 1 200 ? 193.538 125.368 173.510 1.00 146.94 ? 215  ASP A HB3  1 
ATOM   3209 N N    . SER A 1 201 ? 192.329 125.129 169.347 1.00 147.52 ? 216  SER A N    1 
ATOM   3210 C CA   . SER A 1 201 ? 192.426 124.711 167.948 1.00 147.23 ? 216  SER A CA   1 
ATOM   3211 C C    . SER A 1 201 ? 191.327 125.356 167.113 1.00 145.44 ? 216  SER A C    1 
ATOM   3212 O O    . SER A 1 201 ? 190.155 125.325 167.488 1.00 148.27 ? 216  SER A O    1 
ATOM   3213 C CB   . SER A 1 201 ? 192.360 123.186 167.871 1.00 150.36 ? 216  SER A CB   1 
ATOM   3214 O OG   . SER A 1 201 ? 192.411 122.745 166.528 1.00 156.23 ? 216  SER A OG   1 
ATOM   3215 H H    . SER A 1 201 ? 191.435 125.036 169.808 1.00 147.44 ? 216  SER A H    1 
ATOM   3216 H HA   . SER A 1 201 ? 193.386 125.019 167.532 1.00 147.20 ? 216  SER A HA   1 
ATOM   3217 H HB2  . SER A 1 201 ? 193.208 122.769 168.415 1.00 147.63 ? 216  SER A HB2  1 
ATOM   3218 H HB3  . SER A 1 201 ? 191.440 122.833 168.336 1.00 147.65 ? 216  SER A HB3  1 
ATOM   3219 H HG   . SER A 1 201 ? 191.513 122.704 166.190 1.00 148.40 ? 216  SER A HG   1 
ATOM   3220 N N    . GLY A 1 202 ? 191.689 125.924 165.965 1.00 133.09 ? 217  GLY A N    1 
ATOM   3221 C CA   . GLY A 1 202 ? 190.796 126.786 165.189 1.00 135.16 ? 217  GLY A CA   1 
ATOM   3222 C C    . GLY A 1 202 ? 190.557 128.140 165.859 1.00 135.54 ? 217  GLY A C    1 
ATOM   3223 O O    . GLY A 1 202 ? 191.003 128.385 166.976 1.00 142.20 ? 217  GLY A O    1 
ATOM   3224 H H    . GLY A 1 202 ? 192.664 125.887 165.700 1.00 136.37 ? 217  GLY A H    1 
ATOM   3225 H HA2  . GLY A 1 202 ? 191.233 126.962 164.206 1.00 136.73 ? 217  GLY A HA2  1 
ATOM   3226 H HA3  . GLY A 1 202 ? 189.833 126.295 165.046 1.00 136.79 ? 217  GLY A HA3  1 
ATOM   3227 N N    . MET A 1 203 ? 189.884 129.051 165.162 1.00 135.66 ? 218  MET A N    1 
ATOM   3228 C CA   . MET A 1 203 ? 189.644 130.411 165.651 1.00 136.54 ? 218  MET A CA   1 
ATOM   3229 C C    . MET A 1 203 ? 188.341 130.622 166.437 1.00 134.48 ? 218  MET A C    1 
ATOM   3230 O O    . MET A 1 203 ? 188.382 131.336 167.437 1.00 136.59 ? 218  MET A O    1 
ATOM   3231 C CB   . MET A 1 203 ? 189.725 131.398 164.488 1.00 133.38 ? 218  MET A CB   1 
ATOM   3232 C CG   . MET A 1 203 ? 191.155 131.546 163.985 1.00 140.38 ? 218  MET A CG   1 
ATOM   3233 S SD   . MET A 1 203 ? 191.286 132.597 162.528 1.00 160.08 ? 218  MET A SD   1 
ATOM   3234 C CE   . MET A 1 203 ? 193.083 132.634 162.347 1.00 141.55 ? 218  MET A CE   1 
ATOM   3235 H H    . MET A 1 203 ? 189.561 128.805 164.238 1.00 138.63 ? 218  MET A H    1 
ATOM   3236 H HA   . MET A 1 203 ? 190.445 130.681 166.340 1.00 138.98 ? 218  MET A HA   1 
ATOM   3237 H HB2  . MET A 1 203 ? 189.085 131.076 163.666 1.00 137.53 ? 218  MET A HB2  1 
ATOM   3238 H HB3  . MET A 1 203 ? 189.385 132.375 164.831 1.00 137.94 ? 218  MET A HB3  1 
ATOM   3239 H HG2  . MET A 1 203 ? 191.763 131.976 164.782 1.00 138.95 ? 218  MET A HG2  1 
ATOM   3240 H HG3  . MET A 1 203 ? 191.555 130.564 163.734 1.00 138.50 ? 218  MET A HG3  1 
ATOM   3241 H HE1  . MET A 1 203 ? 193.349 133.217 161.465 1.00 138.92 ? 218  MET A HE1  1 
ATOM   3242 H HE2  . MET A 1 203 ? 193.532 133.096 163.227 1.00 138.51 ? 218  MET A HE2  1 
ATOM   3243 H HE3  . MET A 1 203 ? 193.463 131.619 162.234 1.00 139.34 ? 218  MET A HE3  1 
ATOM   3244 N N    . PRO A 1 204 ? 187.176 130.082 166.041 1.00 123.86 ? 219  PRO A N    1 
ATOM   3245 C CA   . PRO A 1 204 ? 185.939 130.297 166.781 1.00 125.39 ? 219  PRO A CA   1 
ATOM   3246 C C    . PRO A 1 204 ? 186.027 129.668 168.168 1.00 125.52 ? 219  PRO A C    1 
ATOM   3247 O O    . PRO A 1 204 ? 186.362 128.493 168.283 1.00 127.42 ? 219  PRO A O    1 
ATOM   3248 C CB   . PRO A 1 204 ? 184.835 129.646 165.952 1.00 128.71 ? 219  PRO A CB   1 
ATOM   3249 C CG   . PRO A 1 204 ? 185.443 129.520 164.562 1.00 132.30 ? 219  PRO A CG   1 
ATOM   3250 C CD   . PRO A 1 204 ? 186.916 129.304 164.850 1.00 128.70 ? 219  PRO A CD   1 
ATOM   3251 H HA   . PRO A 1 204 ? 185.751 131.367 166.858 1.00 128.51 ? 219  PRO A HA   1 
ATOM   3252 H HB2  . PRO A 1 204 ? 184.606 128.649 166.329 1.00 127.78 ? 219  PRO A HB2  1 
ATOM   3253 H HB3  . PRO A 1 204 ? 183.934 130.259 165.942 1.00 129.54 ? 219  PRO A HB3  1 
ATOM   3254 H HG2  . PRO A 1 204 ? 185.021 128.681 164.010 1.00 129.13 ? 219  PRO A HG2  1 
ATOM   3255 H HG3  . PRO A 1 204 ? 185.311 130.455 164.018 1.00 129.54 ? 219  PRO A HG3  1 
ATOM   3256 H HD2  . PRO A 1 204 ? 187.101 128.250 165.056 1.00 128.16 ? 219  PRO A HD2  1 
ATOM   3257 H HD3  . PRO A 1 204 ? 187.506 129.635 163.994 1.00 129.22 ? 219  PRO A HD3  1 
ATOM   3258 N N    . THR A 1 205 ? 185.742 130.413 169.230 1.00 133.58 ? 220  THR A N    1 
ATOM   3259 C CA   . THR A 1 205 ? 185.831 129.878 170.596 1.00 133.44 ? 220  THR A CA   1 
ATOM   3260 C C    . THR A 1 205 ? 184.581 129.112 171.010 1.00 134.89 ? 220  THR A C    1 
ATOM   3261 O O    . THR A 1 205 ? 183.536 129.170 170.366 1.00 139.77 ? 220  THR A O    1 
ATOM   3262 C CB   . THR A 1 205 ? 186.137 130.957 171.626 1.00 133.27 ? 220  THR A CB   1 
ATOM   3263 O OG1  . THR A 1 205 ? 185.069 131.840 171.695 1.00 142.45 ? 220  THR A OG1  1 
ATOM   3264 C CG2  . THR A 1 205 ? 187.399 131.745 171.313 1.00 135.23 ? 220  THR A CG2  1 
ATOM   3265 H H    . THR A 1 205 ? 185.424 131.363 169.102 1.00 134.73 ? 220  THR A H    1 
ATOM   3266 H HA   . THR A 1 205 ? 186.658 129.171 170.646 1.00 134.37 ? 220  THR A HA   1 
ATOM   3267 H HB   . THR A 1 205 ? 186.262 130.492 172.605 1.00 134.12 ? 220  THR A HB   1 
ATOM   3268 H HG1  . THR A 1 205 ? 185.397 132.705 171.952 1.00 135.45 ? 220  THR A HG1  1 
ATOM   3269 H HG21 . THR A 1 205 ? 187.618 132.425 172.136 1.00 134.47 ? 220  THR A HG21 1 
ATOM   3270 H HG22 . THR A 1 205 ? 188.233 131.051 171.204 1.00 134.45 ? 220  THR A HG22 1 
ATOM   3271 H HG23 . THR A 1 205 ? 187.281 132.314 170.390 1.00 135.42 ? 220  THR A HG23 1 
ATOM   3272 N N    . THR A 1 206 ? 184.680 128.378 172.111 1.00 136.24 ? 221  THR A N    1 
ATOM   3273 C CA   . THR A 1 206 ? 183.595 127.607 172.717 1.00 134.26 ? 221  THR A CA   1 
ATOM   3274 C C    . THR A 1 206 ? 183.579 127.800 174.229 1.00 137.92 ? 221  THR A C    1 
ATOM   3275 O O    . THR A 1 206 ? 184.595 128.123 174.834 1.00 147.07 ? 221  THR A O    1 
ATOM   3276 C CB   . THR A 1 206 ? 183.712 126.133 172.337 1.00 142.64 ? 221  THR A CB   1 
ATOM   3277 O OG1  . THR A 1 206 ? 182.657 125.430 172.929 1.00 148.61 ? 221  THR A OG1  1 
ATOM   3278 C CG2  . THR A 1 206 ? 185.007 125.470 172.796 1.00 141.71 ? 221  THR A CG2  1 
ATOM   3279 H H    . THR A 1 206 ? 185.572 128.339 172.582 1.00 139.49 ? 221  THR A H    1 
ATOM   3280 H HA   . THR A 1 206 ? 182.642 127.965 172.330 1.00 139.02 ? 221  THR A HA   1 
ATOM   3281 H HB   . THR A 1 206 ? 183.635 126.038 171.253 1.00 140.58 ? 221  THR A HB   1 
ATOM   3282 H HG1  . THR A 1 206 ? 182.722 124.518 172.638 1.00 141.12 ? 221  THR A HG1  1 
ATOM   3283 H HG21 . THR A 1 206 ? 184.987 124.409 172.546 1.00 140.97 ? 221  THR A HG21 1 
ATOM   3284 H HG22 . THR A 1 206 ? 185.137 125.581 173.873 1.00 139.47 ? 221  THR A HG22 1 
ATOM   3285 H HG23 . THR A 1 206 ? 185.854 125.921 172.281 1.00 139.69 ? 221  THR A HG23 1 
ATOM   3286 N N    . PHE A 1 207 ? 182.417 127.666 174.852 1.00 126.05 ? 222  PHE A N    1 
ATOM   3287 C CA   . PHE A 1 207 ? 182.193 127.996 176.252 1.00 127.09 ? 222  PHE A CA   1 
ATOM   3288 C C    . PHE A 1 207 ? 183.011 127.117 177.213 1.00 128.67 ? 222  PHE A C    1 
ATOM   3289 O O    . PHE A 1 207 ? 182.924 125.894 177.149 1.00 128.19 ? 222  PHE A O    1 
ATOM   3290 C CB   . PHE A 1 207 ? 180.694 127.826 176.486 1.00 124.81 ? 222  PHE A CB   1 
ATOM   3291 C CG   . PHE A 1 207 ? 180.251 128.012 177.914 1.00 123.25 ? 222  PHE A CG   1 
ATOM   3292 C CD1  . PHE A 1 207 ? 180.059 129.305 178.421 1.00 131.09 ? 222  PHE A CD1  1 
ATOM   3293 C CD2  . PHE A 1 207 ? 179.998 126.895 178.724 1.00 125.17 ? 222  PHE A CD2  1 
ATOM   3294 C CE1  . PHE A 1 207 ? 179.590 129.479 179.731 1.00 133.36 ? 222  PHE A CE1  1 
ATOM   3295 C CE2  . PHE A 1 207 ? 179.526 127.070 180.033 1.00 130.08 ? 222  PHE A CE2  1 
ATOM   3296 C CZ   . PHE A 1 207 ? 179.310 128.362 180.533 1.00 130.21 ? 222  PHE A CZ   1 
ATOM   3297 H H    . PHE A 1 207 ? 181.634 127.313 174.321 1.00 129.29 ? 222  PHE A H    1 
ATOM   3298 H HA   . PHE A 1 207 ? 182.455 129.041 176.429 1.00 129.68 ? 222  PHE A HA   1 
ATOM   3299 H HB2  . PHE A 1 207 ? 180.156 128.540 175.863 1.00 129.68 ? 222  PHE A HB2  1 
ATOM   3300 H HB3  . PHE A 1 207 ? 180.398 126.828 176.165 1.00 129.10 ? 222  PHE A HB3  1 
ATOM   3301 H HD1  . PHE A 1 207 ? 180.261 130.166 177.802 1.00 129.87 ? 222  PHE A HD1  1 
ATOM   3302 H HD2  . PHE A 1 207 ? 180.150 125.898 178.336 1.00 128.79 ? 222  PHE A HD2  1 
ATOM   3303 H HE1  . PHE A 1 207 ? 179.440 130.476 180.116 1.00 130.12 ? 222  PHE A HE1  1 
ATOM   3304 H HE2  . PHE A 1 207 ? 179.317 126.209 180.652 1.00 129.57 ? 222  PHE A HE2  1 
ATOM   3305 H HZ   . PHE A 1 207 ? 178.930 128.497 181.534 1.00 129.03 ? 222  PHE A HZ   1 
ATOM   3306 N N    . LEU A 1 208 ? 183.769 127.722 178.132 1.00 142.34 ? 223  LEU A N    1 
ATOM   3307 C CA   . LEU A 1 208 ? 184.408 127.026 179.254 1.00 140.09 ? 223  LEU A CA   1 
ATOM   3308 C C    . LEU A 1 208 ? 183.487 126.980 180.473 1.00 142.34 ? 223  LEU A C    1 
ATOM   3309 O O    . LEU A 1 208 ? 183.127 125.901 180.939 1.00 145.22 ? 223  LEU A O    1 
ATOM   3310 C CB   . LEU A 1 208 ? 185.716 127.719 179.672 1.00 134.53 ? 223  LEU A CB   1 
ATOM   3311 C CG   . LEU A 1 208 ? 186.943 127.465 178.800 1.00 146.06 ? 223  LEU A CG   1 
ATOM   3312 C CD1  . LEU A 1 208 ? 188.116 128.258 179.368 1.00 145.75 ? 223  LEU A CD1  1 
ATOM   3313 C CD2  . LEU A 1 208 ? 187.323 125.988 178.815 1.00 142.69 ? 223  LEU A CD2  1 
ATOM   3314 H H    . LEU A 1 208 ? 183.779 128.732 178.148 1.00 140.58 ? 223  LEU A H    1 
ATOM   3315 H HA   . LEU A 1 208 ? 184.622 125.994 178.979 1.00 141.27 ? 223  LEU A HA   1 
ATOM   3316 H HB2  . LEU A 1 208 ? 185.547 128.794 179.743 1.00 139.82 ? 223  LEU A HB2  1 
ATOM   3317 H HB3  . LEU A 1 208 ? 185.971 127.355 180.667 1.00 139.38 ? 223  LEU A HB3  1 
ATOM   3318 H HG   . LEU A 1 208 ? 186.745 127.793 177.780 1.00 142.09 ? 223  LEU A HG   1 
ATOM   3319 H HD11 . LEU A 1 208 ? 189.000 128.095 178.752 1.00 142.12 ? 223  LEU A HD11 1 
ATOM   3320 H HD12 . LEU A 1 208 ? 188.330 127.934 180.386 1.00 140.91 ? 223  LEU A HD12 1 
ATOM   3321 H HD13 . LEU A 1 208 ? 187.880 129.321 179.368 1.00 140.90 ? 223  LEU A HD13 1 
ATOM   3322 H HD21 . LEU A 1 208 ? 188.306 125.854 178.364 1.00 141.79 ? 223  LEU A HD21 1 
ATOM   3323 H HD22 . LEU A 1 208 ? 186.598 125.407 178.245 1.00 141.16 ? 223  LEU A HD22 1 
ATOM   3324 H HD23 . LEU A 1 208 ? 187.362 125.623 179.841 1.00 140.23 ? 223  LEU A HD23 1 
ATOM   3325 N N    . PHE A 1 209 ? 183.142 128.147 181.020 1.00 136.81 ? 224  PHE A N    1 
ATOM   3326 C CA   . PHE A 1 209 ? 182.393 128.279 182.268 1.00 136.30 ? 224  PHE A CA   1 
ATOM   3327 C C    . PHE A 1 209 ? 181.742 129.657 182.384 1.00 134.62 ? 224  PHE A C    1 
ATOM   3328 O O    . PHE A 1 209 ? 182.121 130.606 181.698 1.00 138.85 ? 224  PHE A O    1 
ATOM   3329 C CB   . PHE A 1 209 ? 183.314 128.032 183.476 1.00 135.03 ? 224  PHE A CB   1 
ATOM   3330 C CG   . PHE A 1 209 ? 184.240 129.180 183.823 1.00 135.47 ? 224  PHE A CG   1 
ATOM   3331 C CD1  . PHE A 1 209 ? 185.468 129.318 183.162 1.00 134.30 ? 224  PHE A CD1  1 
ATOM   3332 C CD2  . PHE A 1 209 ? 183.881 130.113 184.811 1.00 139.97 ? 224  PHE A CD2  1 
ATOM   3333 C CE1  . PHE A 1 209 ? 186.317 130.392 183.460 1.00 136.29 ? 224  PHE A CE1  1 
ATOM   3334 C CE2  . PHE A 1 209 ? 184.739 131.180 185.125 1.00 140.22 ? 224  PHE A CE2  1 
ATOM   3335 C CZ   . PHE A 1 209 ? 185.959 131.318 184.450 1.00 136.07 ? 224  PHE A CZ   1 
ATOM   3336 H H    . PHE A 1 209 ? 183.422 128.999 180.558 1.00 136.47 ? 224  PHE A H    1 
ATOM   3337 H HA   . PHE A 1 209 ? 181.600 127.530 182.279 1.00 137.00 ? 224  PHE A HA   1 
ATOM   3338 H HB2  . PHE A 1 209 ? 182.686 127.831 184.344 1.00 137.02 ? 224  PHE A HB2  1 
ATOM   3339 H HB3  . PHE A 1 209 ? 183.908 127.135 183.307 1.00 136.83 ? 224  PHE A HB3  1 
ATOM   3340 H HD1  . PHE A 1 209 ? 185.764 128.596 182.415 1.00 136.37 ? 224  PHE A HD1  1 
ATOM   3341 H HD2  . PHE A 1 209 ? 182.948 130.005 185.344 1.00 137.64 ? 224  PHE A HD2  1 
ATOM   3342 H HE1  . PHE A 1 209 ? 187.249 130.504 182.928 1.00 137.40 ? 224  PHE A HE1  1 
ATOM   3343 H HE2  . PHE A 1 209 ? 184.468 131.889 185.894 1.00 137.91 ? 224  PHE A HE2  1 
ATOM   3344 H HZ   . PHE A 1 209 ? 186.626 132.129 184.701 1.00 137.09 ? 224  PHE A HZ   1 
ATOM   3345 N N    . SER A 1 210 ? 180.797 129.785 183.311 1.00 133.23 ? 225  SER A N    1 
ATOM   3346 C CA   . SER A 1 210 ? 180.272 131.065 183.772 1.00 137.38 ? 225  SER A CA   1 
ATOM   3347 C C    . SER A 1 210 ? 180.230 131.101 185.292 1.00 137.58 ? 225  SER A C    1 
ATOM   3348 O O    . SER A 1 210 ? 180.213 130.062 185.953 1.00 134.43 ? 225  SER A O    1 
ATOM   3349 C CB   . SER A 1 210 ? 178.891 131.355 183.191 1.00 135.60 ? 225  SER A CB   1 
ATOM   3350 O OG   . SER A 1 210 ? 177.950 130.396 183.635 1.00 132.38 ? 225  SER A OG   1 
ATOM   3351 H H    . SER A 1 210 ? 180.529 128.970 183.844 1.00 135.60 ? 225  SER A H    1 
ATOM   3352 H HA   . SER A 1 210 ? 180.949 131.855 183.444 1.00 136.49 ? 225  SER A HA   1 
ATOM   3353 H HB2  . SER A 1 210 ? 178.570 132.349 183.504 1.00 135.95 ? 225  SER A HB2  1 
ATOM   3354 H HB3  . SER A 1 210 ? 178.948 131.338 182.102 1.00 135.64 ? 225  SER A HB3  1 
ATOM   3355 H HG   . SER A 1 210 ? 177.101 130.595 183.233 1.00 135.59 ? 225  SER A HG   1 
ATOM   3356 N N    . LEU A 1 211 ? 180.258 132.299 185.861 1.00 141.89 ? 226  LEU A N    1 
ATOM   3357 C CA   . LEU A 1 211 ? 180.492 132.506 187.282 1.00 139.44 ? 226  LEU A CA   1 
ATOM   3358 C C    . LEU A 1 211 ? 179.730 133.733 187.766 1.00 143.85 ? 226  LEU A C    1 
ATOM   3359 O O    . LEU A 1 211 ? 179.987 134.846 187.319 1.00 146.83 ? 226  LEU A O    1 
ATOM   3360 C CB   . LEU A 1 211 ? 182.007 132.648 187.477 1.00 137.62 ? 226  LEU A CB   1 
ATOM   3361 C CG   . LEU A 1 211 ? 182.427 133.002 188.904 1.00 142.03 ? 226  LEU A CG   1 
ATOM   3362 C CD1  . LEU A 1 211 ? 181.983 131.917 189.877 1.00 146.46 ? 226  LEU A CD1  1 
ATOM   3363 C CD2  . LEU A 1 211 ? 183.943 133.127 188.966 1.00 137.48 ? 226  LEU A CD2  1 
ATOM   3364 H H    . LEU A 1 211 ? 180.293 133.106 185.255 1.00 141.24 ? 226  LEU A H    1 
ATOM   3365 H HA   . LEU A 1 211 ? 180.141 131.639 187.843 1.00 140.59 ? 226  LEU A HA   1 
ATOM   3366 H HB2  . LEU A 1 211 ? 182.482 131.708 187.196 1.00 140.55 ? 226  LEU A HB2  1 
ATOM   3367 H HB3  . LEU A 1 211 ? 182.378 133.426 186.810 1.00 140.62 ? 226  LEU A HB3  1 
ATOM   3368 H HG   . LEU A 1 211 ? 181.990 133.955 189.203 1.00 141.79 ? 226  LEU A HG   1 
ATOM   3369 H HD11 . LEU A 1 211 ? 180.900 131.940 189.999 1.00 142.22 ? 226  LEU A HD11 1 
ATOM   3370 H HD12 . LEU A 1 211 ? 182.283 130.936 189.509 1.00 142.11 ? 226  LEU A HD12 1 
ATOM   3371 H HD13 . LEU A 1 211 ? 182.439 132.091 190.851 1.00 142.15 ? 226  LEU A HD13 1 
ATOM   3372 H HD21 . LEU A 1 211 ? 184.238 133.396 189.980 1.00 140.73 ? 226  LEU A HD21 1 
ATOM   3373 H HD22 . LEU A 1 211 ? 184.412 132.185 188.681 1.00 141.22 ? 226  LEU A HD22 1 
ATOM   3374 H HD23 . LEU A 1 211 ? 184.274 133.913 188.286 1.00 140.38 ? 226  LEU A HD23 1 
ATOM   3375 N N    . TYR A 1 212 ? 178.787 133.548 188.682 1.00 142.34 ? 227  TYR A N    1 
ATOM   3376 C CA   . TYR A 1 212 ? 178.115 134.667 189.323 1.00 140.85 ? 227  TYR A CA   1 
ATOM   3377 C C    . TYR A 1 212 ? 179.054 135.367 190.302 1.00 141.30 ? 227  TYR A C    1 
ATOM   3378 O O    . TYR A 1 212 ? 179.573 134.733 191.215 1.00 143.65 ? 227  TYR A O    1 
ATOM   3379 C CB   . TYR A 1 212 ? 176.860 134.188 190.040 1.00 140.21 ? 227  TYR A CB   1 
ATOM   3380 C CG   . TYR A 1 212 ? 176.212 135.303 190.823 1.00 136.97 ? 227  TYR A CG   1 
ATOM   3381 C CD1  . TYR A 1 212 ? 175.537 136.329 190.142 1.00 136.28 ? 227  TYR A CD1  1 
ATOM   3382 C CD2  . TYR A 1 212 ? 176.346 135.352 192.219 1.00 136.60 ? 227  TYR A CD2  1 
ATOM   3383 C CE1  . TYR A 1 212 ? 174.986 137.401 190.861 1.00 136.65 ? 227  TYR A CE1  1 
ATOM   3384 C CE2  . TYR A 1 212 ? 175.786 136.419 192.942 1.00 139.99 ? 227  TYR A CE2  1 
ATOM   3385 C CZ   . TYR A 1 212 ? 175.103 137.443 192.262 1.00 141.59 ? 227  TYR A CZ   1 
ATOM   3386 O OH   . TYR A 1 212 ? 174.557 138.474 192.953 1.00 150.29 ? 227  TYR A OH   1 
ATOM   3387 H H    . TYR A 1 212 ? 178.593 132.613 189.016 1.00 140.92 ? 227  TYR A H    1 
ATOM   3388 H HA   . TYR A 1 212 ? 177.809 135.386 188.562 1.00 140.26 ? 227  TYR A HA   1 
ATOM   3389 H HB2  . TYR A 1 212 ? 176.151 133.806 189.306 1.00 140.68 ? 227  TYR A HB2  1 
ATOM   3390 H HB3  . TYR A 1 212 ? 177.118 133.374 190.718 1.00 140.35 ? 227  TYR A HB3  1 
ATOM   3391 H HD1  . TYR A 1 212 ? 175.444 136.296 189.067 1.00 140.49 ? 227  TYR A HD1  1 
ATOM   3392 H HD2  . TYR A 1 212 ? 176.884 134.573 192.739 1.00 140.54 ? 227  TYR A HD2  1 
ATOM   3393 H HE1  . TYR A 1 212 ? 174.460 138.192 190.346 1.00 140.69 ? 227  TYR A HE1  1 
ATOM   3394 H HE2  . TYR A 1 212 ? 175.885 136.454 194.017 1.00 141.32 ? 227  TYR A HE2  1 
ATOM   3395 H HH   . TYR A 1 212 ? 174.628 138.338 193.901 1.00 142.01 ? 227  TYR A HH   1 
ATOM   3396 N N    . LEU A 1 213 ? 179.238 136.675 190.136 1.00 140.91 ? 228  LEU A N    1 
ATOM   3397 C CA   . LEU A 1 213 ? 180.027 137.516 191.036 1.00 141.78 ? 228  LEU A CA   1 
ATOM   3398 C C    . LEU A 1 213 ? 179.158 138.517 191.804 1.00 144.44 ? 228  LEU A C    1 
ATOM   3399 O O    . LEU A 1 213 ? 179.534 138.967 192.883 1.00 145.63 ? 228  LEU A O    1 
ATOM   3400 C CB   . LEU A 1 213 ? 181.059 138.290 190.211 1.00 137.02 ? 228  LEU A CB   1 
ATOM   3401 C CG   . LEU A 1 213 ? 182.053 137.422 189.433 1.00 137.89 ? 228  LEU A CG   1 
ATOM   3402 C CD1  . LEU A 1 213 ? 182.926 138.341 188.594 1.00 136.76 ? 228  LEU A CD1  1 
ATOM   3403 C CD2  . LEU A 1 213 ? 182.959 136.617 190.359 1.00 140.88 ? 228  LEU A CD2  1 
ATOM   3404 H H    . LEU A 1 213 ? 178.791 137.122 189.348 1.00 141.18 ? 228  LEU A H    1 
ATOM   3405 H HA   . LEU A 1 213 ? 180.547 136.906 191.776 1.00 141.40 ? 228  LEU A HA   1 
ATOM   3406 H HB2  . LEU A 1 213 ? 180.526 138.923 189.503 1.00 140.68 ? 228  LEU A HB2  1 
ATOM   3407 H HB3  . LEU A 1 213 ? 181.620 138.941 190.881 1.00 140.68 ? 228  LEU A HB3  1 
ATOM   3408 H HG   . LEU A 1 213 ? 181.526 136.743 188.762 1.00 141.06 ? 228  LEU A HG   1 
ATOM   3409 H HD11 . LEU A 1 213 ? 182.306 138.910 187.904 1.00 140.91 ? 228  LEU A HD11 1 
ATOM   3410 H HD12 . LEU A 1 213 ? 183.634 137.744 188.017 1.00 140.37 ? 228  LEU A HD12 1 
ATOM   3411 H HD13 . LEU A 1 213 ? 183.473 139.027 189.241 1.00 140.79 ? 228  LEU A HD13 1 
ATOM   3412 H HD21 . LEU A 1 213 ? 182.366 135.879 190.900 1.00 141.26 ? 228  LEU A HD21 1 
ATOM   3413 H HD22 . LEU A 1 213 ? 183.455 137.277 191.069 1.00 141.37 ? 228  LEU A HD22 1 
ATOM   3414 H HD23 . LEU A 1 213 ? 183.711 136.091 189.770 1.00 141.00 ? 228  LEU A HD23 1 
ATOM   3415 N N    . GLY A 1 214 ? 178.016 138.912 191.242 1.00 147.38 ? 229  GLY A N    1 
ATOM   3416 C CA   . GLY A 1 214 ? 177.157 139.973 191.769 1.00 146.35 ? 229  GLY A CA   1 
ATOM   3417 C C    . GLY A 1 214 ? 177.705 141.371 191.491 1.00 144.79 ? 229  GLY A C    1 
ATOM   3418 O O    . GLY A 1 214 ? 176.993 142.237 190.989 1.00 141.59 ? 229  GLY A O    1 
ATOM   3419 H H    . GLY A 1 214 ? 177.774 138.523 190.342 1.00 144.80 ? 229  GLY A H    1 
ATOM   3420 H HA2  . GLY A 1 214 ? 176.171 139.901 191.310 1.00 144.91 ? 229  GLY A HA2  1 
ATOM   3421 H HA3  . GLY A 1 214 ? 177.049 139.854 192.846 1.00 144.61 ? 229  GLY A HA3  1 
ATOM   3422 N N    . THR A 1 215 ? 178.982 141.594 191.769 1.00 149.50 ? 230  THR A N    1 
ATOM   3423 C CA   . THR A 1 215 ? 179.669 142.862 191.523 1.00 153.97 ? 230  THR A CA   1 
ATOM   3424 C C    . THR A 1 215 ? 180.138 143.022 190.082 1.00 148.97 ? 230  THR A C    1 
ATOM   3425 O O    . THR A 1 215 ? 180.478 142.053 189.409 1.00 142.43 ? 230  THR A O    1 
ATOM   3426 C CB   . THR A 1 215 ? 180.879 142.994 192.448 1.00 153.41 ? 230  THR A CB   1 
ATOM   3427 O OG1  . THR A 1 215 ? 181.751 141.893 192.301 1.00 155.87 ? 230  THR A OG1  1 
ATOM   3428 C CG2  . THR A 1 215 ? 180.474 143.072 193.918 1.00 148.72 ? 230  THR A CG2  1 
ATOM   3429 H H    . THR A 1 215 ? 179.511 140.847 192.197 1.00 148.84 ? 230  THR A H    1 
ATOM   3430 H HA   . THR A 1 215 ? 178.989 143.684 191.748 1.00 150.12 ? 230  THR A HA   1 
ATOM   3431 H HB   . THR A 1 215 ? 181.418 143.906 192.196 1.00 149.42 ? 230  THR A HB   1 
ATOM   3432 H HG1  . THR A 1 215 ? 182.008 141.838 191.377 1.00 149.99 ? 230  THR A HG1  1 
ATOM   3433 H HG21 . THR A 1 215 ? 181.361 143.232 194.530 1.00 148.95 ? 230  THR A HG21 1 
ATOM   3434 H HG22 . THR A 1 215 ? 179.790 143.907 194.065 1.00 148.89 ? 230  THR A HG22 1 
ATOM   3435 H HG23 . THR A 1 215 ? 179.987 142.148 194.229 1.00 149.16 ? 230  THR A HG23 1 
ATOM   3436 N N    . LEU A 1 216 ? 180.234 144.265 189.624 1.00 148.83 ? 231  LEU A N    1 
ATOM   3437 C CA   . LEU A 1 216 ? 180.798 144.630 188.329 1.00 146.69 ? 231  LEU A CA   1 
ATOM   3438 C C    . LEU A 1 216 ? 182.328 144.481 188.332 1.00 151.02 ? 231  LEU A C    1 
ATOM   3439 O O    . LEU A 1 216 ? 182.996 145.090 189.166 1.00 149.84 ? 231  LEU A O    1 
ATOM   3440 C CB   . LEU A 1 216 ? 180.343 146.075 188.063 1.00 144.85 ? 231  LEU A CB   1 
ATOM   3441 C CG   . LEU A 1 216 ? 180.569 146.568 186.632 1.00 145.69 ? 231  LEU A CG   1 
ATOM   3442 C CD1  . LEU A 1 216 ? 179.588 145.917 185.658 1.00 147.83 ? 231  LEU A CD1  1 
ATOM   3443 C CD2  . LEU A 1 216 ? 180.357 148.078 186.577 1.00 146.08 ? 231  LEU A CD2  1 
ATOM   3444 H H    . LEU A 1 216 ? 179.948 145.020 190.232 1.00 147.33 ? 231  LEU A H    1 
ATOM   3445 H HA   . LEU A 1 216 ? 180.380 143.971 187.568 1.00 146.24 ? 231  LEU A HA   1 
ATOM   3446 H HB2  . LEU A 1 216 ? 179.280 146.164 188.284 1.00 146.85 ? 231  LEU A HB2  1 
ATOM   3447 H HB3  . LEU A 1 216 ? 180.877 146.733 188.748 1.00 146.21 ? 231  LEU A HB3  1 
ATOM   3448 H HG   . LEU A 1 216 ? 181.591 146.348 186.323 1.00 146.77 ? 231  LEU A HG   1 
ATOM   3449 H HD11 . LEU A 1 216 ? 179.761 146.305 184.655 1.00 147.12 ? 231  LEU A HD11 1 
ATOM   3450 H HD12 . LEU A 1 216 ? 178.563 146.137 185.956 1.00 146.63 ? 231  LEU A HD12 1 
ATOM   3451 H HD13 . LEU A 1 216 ? 179.736 144.838 185.641 1.00 146.69 ? 231  LEU A HD13 1 
ATOM   3452 H HD21 . LEU A 1 216 ? 180.521 148.434 185.560 1.00 147.03 ? 231  LEU A HD21 1 
ATOM   3453 H HD22 . LEU A 1 216 ? 179.343 148.326 186.889 1.00 146.76 ? 231  LEU A HD22 1 
ATOM   3454 H HD23 . LEU A 1 216 ? 181.069 148.572 187.238 1.00 146.39 ? 231  LEU A HD23 1 
ATOM   3455 N N    . LEU A 1 217 ? 182.906 143.712 187.408 1.00 143.78 ? 232  LEU A N    1 
ATOM   3456 C CA   . LEU A 1 217 ? 184.348 143.750 187.138 1.00 134.37 ? 232  LEU A CA   1 
ATOM   3457 C C    . LEU A 1 217 ? 184.682 145.043 186.401 1.00 133.21 ? 232  LEU A C    1 
ATOM   3458 O O    . LEU A 1 217 ? 183.893 145.487 185.569 1.00 137.55 ? 232  LEU A O    1 
ATOM   3459 C CB   . LEU A 1 217 ? 184.760 142.564 186.263 1.00 132.67 ? 232  LEU A CB   1 
ATOM   3460 C CG   . LEU A 1 217 ? 184.569 141.194 186.920 1.00 131.73 ? 232  LEU A CG   1 
ATOM   3461 C CD1  . LEU A 1 217 ? 184.660 140.121 185.846 1.00 135.98 ? 232  LEU A CD1  1 
ATOM   3462 C CD2  . LEU A 1 217 ? 185.644 140.932 187.970 1.00 130.04 ? 232  LEU A CD2  1 
ATOM   3463 H H    . LEU A 1 217 ? 182.317 143.240 186.736 1.00 137.19 ? 232  LEU A H    1 
ATOM   3464 H HA   . LEU A 1 217 ? 184.907 143.725 188.073 1.00 135.59 ? 232  LEU A HA   1 
ATOM   3465 H HB2  . LEU A 1 217 ? 184.175 142.600 185.344 1.00 135.77 ? 232  LEU A HB2  1 
ATOM   3466 H HB3  . LEU A 1 217 ? 185.808 142.674 185.982 1.00 135.60 ? 232  LEU A HB3  1 
ATOM   3467 H HG   . LEU A 1 217 ? 183.586 141.130 187.385 1.00 135.61 ? 232  LEU A HG   1 
ATOM   3468 H HD11 . LEU A 1 217 ? 184.543 139.135 186.296 1.00 135.89 ? 232  LEU A HD11 1 
ATOM   3469 H HD12 . LEU A 1 217 ? 183.860 140.274 185.122 1.00 136.20 ? 232  LEU A HD12 1 
ATOM   3470 H HD13 . LEU A 1 217 ? 185.622 140.173 185.337 1.00 135.77 ? 232  LEU A HD13 1 
ATOM   3471 H HD21 . LEU A 1 217 ? 185.554 141.655 188.781 1.00 135.59 ? 232  LEU A HD21 1 
ATOM   3472 H HD22 . LEU A 1 217 ? 186.632 141.007 187.517 1.00 135.01 ? 232  LEU A HD22 1 
ATOM   3473 H HD23 . LEU A 1 217 ? 185.520 139.930 188.380 1.00 135.50 ? 232  LEU A HD23 1 
ATOM   3474 N N    . SER A 1 218 ? 185.842 145.640 186.653 1.00 141.44 ? 233  SER A N    1 
ATOM   3475 C CA   . SER A 1 218 ? 186.180 146.947 186.081 1.00 145.41 ? 233  SER A CA   1 
ATOM   3476 C C    . SER A 1 218 ? 187.558 147.013 185.440 1.00 144.29 ? 233  SER A C    1 
ATOM   3477 O O    . SER A 1 218 ? 187.745 147.826 184.540 1.00 146.81 ? 233  SER A O    1 
ATOM   3478 C CB   . SER A 1 218 ? 186.022 148.040 187.137 1.00 146.75 ? 233  SER A CB   1 
ATOM   3479 O OG   . SER A 1 218 ? 186.910 147.856 188.223 1.00 148.81 ? 233  SER A OG   1 
ATOM   3480 H H    . SER A 1 218 ? 186.474 145.221 187.320 1.00 144.08 ? 233  SER A H    1 
ATOM   3481 H HA   . SER A 1 218 ? 185.478 147.190 185.283 1.00 144.35 ? 233  SER A HA   1 
ATOM   3482 H HB2  . SER A 1 218 ? 186.206 149.013 186.683 1.00 145.06 ? 233  SER A HB2  1 
ATOM   3483 H HB3  . SER A 1 218 ? 184.997 148.024 187.509 1.00 144.67 ? 233  SER A HB3  1 
ATOM   3484 H HG   . SER A 1 218 ? 187.780 148.161 187.956 1.00 145.28 ? 233  SER A HG   1 
ATOM   3485 N N    . HIS A 1 219 ? 188.497 146.146 185.805 1.00 138.25 ? 234  HIS A N    1 
ATOM   3486 C CA   . HIS A 1 219 ? 189.854 146.186 185.268 1.00 135.73 ? 234  HIS A CA   1 
ATOM   3487 C C    . HIS A 1 219 ? 190.380 144.808 184.931 1.00 140.90 ? 234  HIS A C    1 
ATOM   3488 O O    . HIS A 1 219 ? 190.011 143.822 185.558 1.00 148.87 ? 234  HIS A O    1 
ATOM   3489 C CB   . HIS A 1 219 ? 190.801 146.858 186.261 1.00 137.04 ? 234  HIS A CB   1 
ATOM   3490 C CG   . HIS A 1 219 ? 190.511 148.315 186.447 1.00 138.97 ? 234  HIS A CG   1 
ATOM   3491 N ND1  . HIS A 1 219 ? 189.533 148.847 187.290 1.00 142.17 ? 234  HIS A ND1  1 
ATOM   3492 C CD2  . HIS A 1 219 ? 191.038 149.313 185.691 1.00 143.11 ? 234  HIS A CD2  1 
ATOM   3493 C CE1  . HIS A 1 219 ? 189.514 150.164 187.034 1.00 144.41 ? 234  HIS A CE1  1 
ATOM   3494 N NE2  . HIS A 1 219 ? 190.403 150.468 186.076 1.00 145.98 ? 234  HIS A NE2  1 
ATOM   3495 H H    . HIS A 1 219 ? 188.290 145.454 186.511 1.00 142.08 ? 234  HIS A H    1 
ATOM   3496 H HA   . HIS A 1 219 ? 189.862 146.767 184.347 1.00 141.02 ? 234  HIS A HA   1 
ATOM   3497 H HB2  . HIS A 1 219 ? 190.732 146.353 187.224 1.00 141.71 ? 234  HIS A HB2  1 
ATOM   3498 H HB3  . HIS A 1 219 ? 191.824 146.760 185.899 1.00 140.91 ? 234  HIS A HB3  1 
ATOM   3499 H HD2  . HIS A 1 219 ? 191.761 149.200 184.898 1.00 142.11 ? 234  HIS A HD2  1 
ATOM   3500 H HE1  . HIS A 1 219 ? 188.855 150.877 187.507 1.00 142.24 ? 234  HIS A HE1  1 
ATOM   3501 H HE2  . HIS A 1 219 ? 190.515 151.378 185.655 1.00 142.25 ? 234  HIS A HE2  1 
ATOM   3502 N N    . TYR A 1 220 ? 191.315 144.753 183.993 1.00 128.49 ? 235  TYR A N    1 
ATOM   3503 C CA   . TYR A 1 220 ? 192.112 143.572 183.724 1.00 126.32 ? 235  TYR A CA   1 
ATOM   3504 C C    . TYR A 1 220 ? 193.563 143.957 183.518 1.00 127.75 ? 235  TYR A C    1 
ATOM   3505 O O    . TYR A 1 220 ? 193.883 145.104 183.211 1.00 138.15 ? 235  TYR A O    1 
ATOM   3506 C CB   . TYR A 1 220 ? 191.561 142.801 182.531 1.00 124.96 ? 235  TYR A CB   1 
ATOM   3507 C CG   . TYR A 1 220 ? 191.781 143.471 181.200 1.00 123.35 ? 235  TYR A CG   1 
ATOM   3508 C CD1  . TYR A 1 220 ? 190.866 144.426 180.736 1.00 130.46 ? 235  TYR A CD1  1 
ATOM   3509 C CD2  . TYR A 1 220 ? 192.903 143.142 180.428 1.00 125.73 ? 235  TYR A CD2  1 
ATOM   3510 C CE1  . TYR A 1 220 ? 191.058 145.037 179.489 1.00 129.87 ? 235  TYR A CE1  1 
ATOM   3511 C CE2  . TYR A 1 220 ? 193.105 143.762 179.187 1.00 127.60 ? 235  TYR A CE2  1 
ATOM   3512 C CZ   . TYR A 1 220 ? 192.177 144.707 178.712 1.00 125.08 ? 235  TYR A CZ   1 
ATOM   3513 O OH   . TYR A 1 220 ? 192.366 145.326 177.522 1.00 129.18 ? 235  TYR A OH   1 
ATOM   3514 H H    . TYR A 1 220 ? 191.570 145.604 183.512 1.00 131.05 ? 235  TYR A H    1 
ATOM   3515 H HA   . TYR A 1 220 ? 192.073 142.918 184.595 1.00 131.10 ? 235  TYR A HA   1 
ATOM   3516 H HB2  . TYR A 1 220 ? 192.045 141.825 182.505 1.00 129.97 ? 235  TYR A HB2  1 
ATOM   3517 H HB3  . TYR A 1 220 ? 190.495 142.629 182.676 1.00 130.89 ? 235  TYR A HB3  1 
ATOM   3518 H HD1  . TYR A 1 220 ? 190.016 144.696 181.344 1.00 131.61 ? 235  TYR A HD1  1 
ATOM   3519 H HD2  . TYR A 1 220 ? 193.616 142.417 180.789 1.00 129.52 ? 235  TYR A HD2  1 
ATOM   3520 H HE1  . TYR A 1 220 ? 190.351 145.765 179.118 1.00 131.26 ? 235  TYR A HE1  1 
ATOM   3521 H HE2  . TYR A 1 220 ? 193.982 143.507 178.609 1.00 131.10 ? 235  TYR A HE2  1 
ATOM   3522 H HH   . TYR A 1 220 ? 193.064 144.902 177.018 1.00 131.25 ? 235  TYR A HH   1 
ATOM   3523 N N    . TYR A 1 221 ? 194.452 142.997 183.715 1.00 131.69 ? 236  TYR A N    1 
ATOM   3524 C CA   . TYR A 1 221 ? 195.881 143.205 183.601 1.00 132.87 ? 236  TYR A CA   1 
ATOM   3525 C C    . TYR A 1 221 ? 196.570 141.909 183.175 1.00 134.84 ? 236  TYR A C    1 
ATOM   3526 O O    . TYR A 1 221 ? 196.220 140.832 183.650 1.00 142.89 ? 236  TYR A O    1 
ATOM   3527 C CB   . TYR A 1 221 ? 196.385 143.738 184.943 1.00 131.18 ? 236  TYR A CB   1 
ATOM   3528 C CG   . TYR A 1 221 ? 197.857 144.030 184.939 1.00 125.31 ? 236  TYR A CG   1 
ATOM   3529 C CD1  . TYR A 1 221 ? 198.349 145.046 184.111 1.00 129.15 ? 236  TYR A CD1  1 
ATOM   3530 C CD2  . TYR A 1 221 ? 198.727 143.274 185.732 1.00 130.85 ? 236  TYR A CD2  1 
ATOM   3531 C CE1  . TYR A 1 221 ? 199.725 145.295 184.062 1.00 133.44 ? 236  TYR A CE1  1 
ATOM   3532 C CE2  . TYR A 1 221 ? 200.111 143.501 185.662 1.00 138.56 ? 236  TYR A CE2  1 
ATOM   3533 C CZ   . TYR A 1 221 ? 200.608 144.508 184.817 1.00 136.25 ? 236  TYR A CZ   1 
ATOM   3534 O OH   . TYR A 1 221 ? 201.932 144.762 184.748 1.00 141.93 ? 236  TYR A OH   1 
ATOM   3535 H H    . TYR A 1 221 ? 194.128 142.087 184.011 1.00 135.21 ? 236  TYR A H    1 
ATOM   3536 H HA   . TYR A 1 221 ? 196.074 143.953 182.833 1.00 135.40 ? 236  TYR A HA   1 
ATOM   3537 H HB2  . TYR A 1 221 ? 195.859 144.662 185.182 1.00 135.59 ? 236  TYR A HB2  1 
ATOM   3538 H HB3  . TYR A 1 221 ? 196.157 143.018 185.729 1.00 135.31 ? 236  TYR A HB3  1 
ATOM   3539 H HD1  . TYR A 1 221 ? 197.672 145.634 183.510 1.00 135.10 ? 236  TYR A HD1  1 
ATOM   3540 H HD2  . TYR A 1 221 ? 198.328 142.523 186.399 1.00 135.61 ? 236  TYR A HD2  1 
ATOM   3541 H HE1  . TYR A 1 221 ? 200.118 146.082 183.437 1.00 136.27 ? 236  TYR A HE1  1 
ATOM   3542 H HE2  . TYR A 1 221 ? 200.796 142.912 186.255 1.00 137.20 ? 236  TYR A HE2  1 
ATOM   3543 H HH   . TYR A 1 221 ? 202.085 145.646 184.408 1.00 136.79 ? 236  TYR A HH   1 
ATOM   3544 N N    . VAL A 1 222 ? 197.553 141.989 182.282 1.00 125.69 ? 237  VAL A N    1 
ATOM   3545 C CA   . VAL A 1 222 ? 198.307 140.823 181.803 1.00 127.43 ? 237  VAL A CA   1 
ATOM   3546 C C    . VAL A 1 222 ? 199.646 140.822 182.519 1.00 127.47 ? 237  VAL A C    1 
ATOM   3547 O O    . VAL A 1 222 ? 200.409 141.774 182.392 1.00 125.22 ? 237  VAL A O    1 
ATOM   3548 C CB   . VAL A 1 222 ? 198.480 140.875 180.280 1.00 120.70 ? 237  VAL A CB   1 
ATOM   3549 C CG1  . VAL A 1 222 ? 199.338 139.726 179.758 1.00 127.98 ? 237  VAL A CG1  1 
ATOM   3550 C CG2  . VAL A 1 222 ? 197.111 140.775 179.606 1.00 123.55 ? 237  VAL A CG2  1 
ATOM   3551 H H    . VAL A 1 222 ? 197.841 142.902 181.962 1.00 128.03 ? 237  VAL A H    1 
ATOM   3552 H HA   . VAL A 1 222 ? 197.783 139.900 182.049 1.00 129.24 ? 237  VAL A HA   1 
ATOM   3553 H HB   . VAL A 1 222 ? 198.944 141.818 179.994 1.00 126.93 ? 237  VAL A HB   1 
ATOM   3554 H HG11 . VAL A 1 222 ? 199.392 139.772 178.670 1.00 128.42 ? 237  VAL A HG11 1 
ATOM   3555 H HG12 . VAL A 1 222 ? 198.898 138.774 180.055 1.00 129.08 ? 237  VAL A HG12 1 
ATOM   3556 H HG13 . VAL A 1 222 ? 200.350 139.804 180.153 1.00 128.68 ? 237  VAL A HG13 1 
ATOM   3557 H HG21 . VAL A 1 222 ? 196.486 141.622 179.890 1.00 127.45 ? 237  VAL A HG21 1 
ATOM   3558 H HG22 . VAL A 1 222 ? 196.618 139.848 179.897 1.00 128.14 ? 237  VAL A HG22 1 
ATOM   3559 H HG23 . VAL A 1 222 ? 197.231 140.786 178.522 1.00 128.62 ? 237  VAL A HG23 1 
ATOM   3560 N N    . LEU A 1 223 ? 199.940 139.787 183.301 1.00 136.80 ? 238  LEU A N    1 
ATOM   3561 C CA   . LEU A 1 223 ? 201.103 139.800 184.181 1.00 129.25 ? 238  LEU A CA   1 
ATOM   3562 C C    . LEU A 1 223 ? 202.404 139.741 183.379 1.00 130.15 ? 238  LEU A C    1 
ATOM   3563 O O    . LEU A 1 223 ? 202.528 138.894 182.493 1.00 134.09 ? 238  LEU A O    1 
ATOM   3564 C CB   . LEU A 1 223 ? 201.057 138.632 185.180 1.00 132.24 ? 238  LEU A CB   1 
ATOM   3565 C CG   . LEU A 1 223 ? 199.816 138.558 186.080 1.00 134.72 ? 238  LEU A CG   1 
ATOM   3566 C CD1  . LEU A 1 223 ? 200.049 137.546 187.195 1.00 137.30 ? 238  LEU A CD1  1 
ATOM   3567 C CD2  . LEU A 1 223 ? 199.525 139.890 186.748 1.00 136.76 ? 238  LEU A CD2  1 
ATOM   3568 H H    . LEU A 1 223 ? 199.334 138.979 183.294 1.00 136.66 ? 238  LEU A H    1 
ATOM   3569 H HA   . LEU A 1 223 ? 201.079 140.730 184.748 1.00 134.59 ? 238  LEU A HA   1 
ATOM   3570 H HB2  . LEU A 1 223 ? 201.136 137.695 184.629 1.00 135.57 ? 238  LEU A HB2  1 
ATOM   3571 H HB3  . LEU A 1 223 ? 201.939 138.714 185.816 1.00 135.67 ? 238  LEU A HB3  1 
ATOM   3572 H HG   . LEU A 1 223 ? 198.951 138.254 185.491 1.00 135.61 ? 238  LEU A HG   1 
ATOM   3573 H HD11 . LEU A 1 223 ? 199.159 137.470 187.819 1.00 137.04 ? 238  LEU A HD11 1 
ATOM   3574 H HD12 . LEU A 1 223 ? 200.253 136.563 186.771 1.00 136.38 ? 238  LEU A HD12 1 
ATOM   3575 H HD13 . LEU A 1 223 ? 200.894 137.851 187.812 1.00 136.07 ? 238  LEU A HD13 1 
ATOM   3576 H HD21 . LEU A 1 223 ? 198.730 139.778 187.484 1.00 136.33 ? 238  LEU A HD21 1 
ATOM   3577 H HD22 . LEU A 1 223 ? 199.189 140.587 185.980 1.00 135.96 ? 238  LEU A HD22 1 
ATOM   3578 H HD23 . LEU A 1 223 ? 200.426 140.270 187.230 1.00 136.16 ? 238  LEU A HD23 1 
ATOM   3579 N N    . PRO A 1 224 ? 203.410 140.565 183.699 1.00 129.18 ? 239  PRO A N    1 
ATOM   3580 C CA   . PRO A 1 224 ? 204.759 140.355 183.228 1.00 132.27 ? 239  PRO A CA   1 
ATOM   3581 C C    . PRO A 1 224 ? 205.250 138.958 183.575 1.00 136.01 ? 239  PRO A C    1 
ATOM   3582 O O    . PRO A 1 224 ? 204.979 138.447 184.662 1.00 139.69 ? 239  PRO A O    1 
ATOM   3583 C CB   . PRO A 1 224 ? 205.616 141.424 183.899 1.00 132.77 ? 239  PRO A CB   1 
ATOM   3584 C CG   . PRO A 1 224 ? 204.609 142.529 184.173 1.00 132.63 ? 239  PRO A CG   1 
ATOM   3585 C CD   . PRO A 1 224 ? 203.351 141.748 184.524 1.00 131.72 ? 239  PRO A CD   1 
ATOM   3586 H HA   . PRO A 1 224 ? 204.772 140.500 182.148 1.00 135.88 ? 239  PRO A HA   1 
ATOM   3587 H HB2  . PRO A 1 224 ? 206.014 141.059 184.846 1.00 136.15 ? 239  PRO A HB2  1 
ATOM   3588 H HB3  . PRO A 1 224 ? 206.422 141.764 183.249 1.00 136.88 ? 239  PRO A HB3  1 
ATOM   3589 H HG2  . PRO A 1 224 ? 204.927 143.182 184.986 1.00 136.60 ? 239  PRO A HG2  1 
ATOM   3590 H HG3  . PRO A 1 224 ? 204.442 143.107 183.263 1.00 136.58 ? 239  PRO A HG3  1 
ATOM   3591 H HD2  . PRO A 1 224 ? 203.367 141.463 185.576 1.00 136.39 ? 239  PRO A HD2  1 
ATOM   3592 H HD3  . PRO A 1 224 ? 202.465 142.339 184.295 1.00 136.27 ? 239  PRO A HD3  1 
ATOM   3593 N N    . LEU A 1 225 ? 205.995 138.345 182.668 1.00 150.49 ? 240  LEU A N    1 
ATOM   3594 C CA   . LEU A 1 225 ? 206.621 137.047 182.871 1.00 148.14 ? 240  LEU A CA   1 
ATOM   3595 C C    . LEU A 1 225 ? 208.128 137.243 182.859 1.00 150.22 ? 240  LEU A C    1 
ATOM   3596 O O    . LEU A 1 225 ? 208.664 137.846 181.936 1.00 157.01 ? 240  LEU A O    1 
ATOM   3597 C CB   . LEU A 1 225 ? 206.094 136.102 181.791 1.00 146.84 ? 240  LEU A CB   1 
ATOM   3598 C CG   . LEU A 1 225 ? 206.508 134.633 181.931 1.00 149.94 ? 240  LEU A CG   1 
ATOM   3599 C CD1  . LEU A 1 225 ? 205.559 133.773 181.101 1.00 150.53 ? 240  LEU A CD1  1 
ATOM   3600 C CD2  . LEU A 1 225 ? 207.916 134.352 181.422 1.00 154.30 ? 240  LEU A CD2  1 
ATOM   3601 H H    . LEU A 1 225 ? 206.186 138.830 181.803 1.00 151.85 ? 240  LEU A H    1 
ATOM   3602 H HA   . LEU A 1 225 ? 206.334 136.640 183.841 1.00 151.37 ? 240  LEU A HA   1 
ATOM   3603 H HB2  . LEU A 1 225 ? 205.006 136.147 181.838 1.00 151.03 ? 240  LEU A HB2  1 
ATOM   3604 H HB3  . LEU A 1 225 ? 206.396 136.476 180.813 1.00 151.62 ? 240  LEU A HB3  1 
ATOM   3605 H HG   . LEU A 1 225 ? 206.436 134.328 182.975 1.00 152.15 ? 240  LEU A HG   1 
ATOM   3606 H HD11 . LEU A 1 225 ? 204.536 133.895 181.456 1.00 151.37 ? 240  LEU A HD11 1 
ATOM   3607 H HD12 . LEU A 1 225 ? 205.831 132.722 181.198 1.00 152.26 ? 240  LEU A HD12 1 
ATOM   3608 H HD13 . LEU A 1 225 ? 205.613 134.061 180.051 1.00 151.86 ? 240  LEU A HD13 1 
ATOM   3609 H HD21 . LEU A 1 225 ? 208.663 134.816 182.066 1.00 152.63 ? 240  LEU A HD21 1 
ATOM   3610 H HD22 . LEU A 1 225 ? 208.090 133.276 181.434 1.00 152.91 ? 240  LEU A HD22 1 
ATOM   3611 H HD23 . LEU A 1 225 ? 208.030 134.718 180.401 1.00 152.92 ? 240  LEU A HD23 1 
ATOM   3612 N N    . THR A 1 226 ? 208.835 136.759 183.876 1.00 165.09 ? 241  THR A N    1 
ATOM   3613 C CA   . THR A 1 226 ? 210.299 136.893 183.932 1.00 166.14 ? 241  THR A CA   1 
ATOM   3614 C C    . THR A 1 226 ? 210.984 135.576 183.619 1.00 165.35 ? 241  THR A C    1 
ATOM   3615 O O    . THR A 1 226 ? 210.554 134.518 184.073 1.00 170.29 ? 241  THR A O    1 
ATOM   3616 C CB   . THR A 1 226 ? 210.802 137.492 185.240 1.00 169.94 ? 241  THR A CB   1 
ATOM   3617 O OG1  . THR A 1 226 ? 210.475 136.657 186.322 1.00 179.13 ? 241  THR A OG1  1 
ATOM   3618 C CG2  . THR A 1 226 ? 210.207 138.872 185.486 1.00 167.18 ? 241  THR A CG2  1 
ATOM   3619 H H    . THR A 1 226 ? 208.353 136.237 184.594 1.00 167.27 ? 241  THR A H    1 
ATOM   3620 H HA   . THR A 1 226 ? 210.612 137.593 183.158 1.00 167.09 ? 241  THR A HA   1 
ATOM   3621 H HB   . THR A 1 226 ? 211.887 137.589 185.185 1.00 168.01 ? 241  THR A HB   1 
ATOM   3622 H HG1  . THR A 1 226 ? 209.517 136.599 186.346 1.00 168.80 ? 241  THR A HG1  1 
ATOM   3623 H HG21 . THR A 1 226 ? 210.709 139.336 186.335 1.00 167.78 ? 241  THR A HG21 1 
ATOM   3624 H HG22 . THR A 1 226 ? 209.139 138.805 185.689 1.00 167.41 ? 241  THR A HG22 1 
ATOM   3625 H HG23 . THR A 1 226 ? 210.363 139.503 184.611 1.00 167.24 ? 241  THR A HG23 1 
ATOM   3626 N N    . CYS A 1 227 ? 212.014 135.620 182.783 1.00 172.22 ? 242  CYS A N    1 
ATOM   3627 C CA   . CYS A 1 227 ? 212.624 134.420 182.234 1.00 175.50 ? 242  CYS A CA   1 
ATOM   3628 C C    . CYS A 1 227 ? 214.093 134.641 181.895 1.00 176.83 ? 242  CYS A C    1 
ATOM   3629 O O    . CYS A 1 227 ? 214.448 135.691 181.356 1.00 177.86 ? 242  CYS A O    1 
ATOM   3630 C CB   . CYS A 1 227 ? 211.847 134.054 180.969 1.00 182.88 ? 242  CYS A CB   1 
ATOM   3631 S SG   . CYS A 1 227 ? 212.060 132.369 180.392 1.00 203.01 ? 242  CYS A SG   1 
ATOM   3632 H H    . CYS A 1 227 ? 212.333 136.514 182.437 1.00 178.24 ? 242  CYS A H    1 
ATOM   3633 H HA   . CYS A 1 227 ? 212.546 133.602 182.951 1.00 179.08 ? 242  CYS A HA   1 
ATOM   3634 H HB2  . CYS A 1 227 ? 210.782 134.200 181.149 1.00 179.99 ? 242  CYS A HB2  1 
ATOM   3635 H HB3  . CYS A 1 227 ? 212.136 134.727 180.162 1.00 179.50 ? 242  CYS A HB3  1 
ATOM   3636 N N    . ASN A 1 228 ? 214.933 133.633 182.103 1.00 176.40 ? 243  ASN A N    1 
ATOM   3637 C CA   . ASN A 1 228 ? 216.304 133.667 181.597 1.00 176.71 ? 243  ASN A CA   1 
ATOM   3638 C C    . ASN A 1 228 ? 216.383 133.337 180.089 1.00 177.10 ? 243  ASN A C    1 
ATOM   3639 O O    . ASN A 1 228 ? 217.364 133.688 179.438 1.00 173.91 ? 243  ASN A O    1 
ATOM   3640 C CB   . ASN A 1 228 ? 217.167 132.728 182.442 1.00 176.87 ? 243  ASN A CB   1 
ATOM   3641 C CG   . ASN A 1 228 ? 217.346 133.191 183.880 1.00 178.50 ? 243  ASN A CG   1 
ATOM   3642 O OD1  . ASN A 1 228 ? 216.936 134.267 184.291 1.00 178.40 ? 243  ASN A OD1  1 
ATOM   3643 N ND2  . ASN A 1 228 ? 217.990 132.389 184.691 1.00 175.06 ? 243  ASN A ND2  1 
ATOM   3644 H H    . ASN A 1 228 ? 214.612 132.809 182.591 1.00 176.27 ? 243  ASN A H    1 
ATOM   3645 H HA   . ASN A 1 228 ? 216.704 134.675 181.710 1.00 175.73 ? 243  ASN A HA   1 
ATOM   3646 H HB2  . ASN A 1 228 ? 216.734 131.727 182.444 1.00 176.09 ? 243  ASN A HB2  1 
ATOM   3647 H HB3  . ASN A 1 228 ? 218.160 132.660 181.996 1.00 175.83 ? 243  ASN A HB3  1 
ATOM   3648 H HD21 . ASN A 1 228 ? 218.350 131.508 184.353 1.00 175.64 ? 243  ASN A HD21 1 
ATOM   3649 H HD22 . ASN A 1 228 ? 218.163 132.694 185.638 1.00 175.76 ? 243  ASN A HD22 1 
ATOM   3650 N N    . ALA A 1 229 ? 215.352 132.694 179.529 1.00 180.56 ? 244  ALA A N    1 
ATOM   3651 C CA   . ALA A 1 229 ? 215.144 132.469 178.094 1.00 178.91 ? 244  ALA A CA   1 
ATOM   3652 C C    . ALA A 1 229 ? 214.206 133.535 177.482 1.00 178.04 ? 244  ALA A C    1 
ATOM   3653 O O    . ALA A 1 229 ? 213.954 134.565 178.108 1.00 177.87 ? 244  ALA A O    1 
ATOM   3654 C CB   . ALA A 1 229 ? 214.607 131.039 177.948 1.00 177.26 ? 244  ALA A CB   1 
ATOM   3655 H H    . ALA A 1 229 ? 214.588 132.435 180.138 1.00 177.55 ? 244  ALA A H    1 
ATOM   3656 H HA   . ALA A 1 229 ? 216.098 132.528 177.570 1.00 177.11 ? 244  ALA A HA   1 
ATOM   3657 H HB1  . ALA A 1 229 ? 215.287 130.350 178.448 1.00 177.30 ? 244  ALA A HB1  1 
ATOM   3658 H HB2  . ALA A 1 229 ? 214.550 130.754 176.898 1.00 176.73 ? 244  ALA A HB2  1 
ATOM   3659 H HB3  . ALA A 1 229 ? 213.614 130.961 178.390 1.00 177.35 ? 244  ALA A HB3  1 
ATOM   3660 N N    . ILE A 1 230 ? 213.642 133.286 176.295 1.00 166.17 ? 245  ILE A N    1 
ATOM   3661 C CA   . ILE A 1 230 ? 212.694 134.164 175.586 1.00 166.56 ? 245  ILE A CA   1 
ATOM   3662 C C    . ILE A 1 230 ? 213.328 135.523 175.261 1.00 166.66 ? 245  ILE A C    1 
ATOM   3663 O O    . ILE A 1 230 ? 212.880 136.569 175.735 1.00 168.89 ? 245  ILE A O    1 
ATOM   3664 C CB   . ILE A 1 230 ? 211.330 134.283 176.306 1.00 164.10 ? 245  ILE A CB   1 
ATOM   3665 C CG1  . ILE A 1 230 ? 210.820 132.927 176.820 1.00 162.56 ? 245  ILE A CG1  1 
ATOM   3666 C CG2  . ILE A 1 230 ? 210.287 134.892 175.353 1.00 161.33 ? 245  ILE A CG2  1 
ATOM   3667 C CD1  . ILE A 1 230 ? 209.482 133.011 177.562 1.00 161.87 ? 245  ILE A CD1  1 
ATOM   3668 H H    . ILE A 1 230 ? 213.911 132.444 175.808 1.00 164.90 ? 245  ILE A H    1 
ATOM   3669 H HA   . ILE A 1 230 ? 212.498 133.684 174.627 1.00 165.01 ? 245  ILE A HA   1 
ATOM   3670 H HB   . ILE A 1 230 ? 211.439 134.939 177.169 1.00 164.69 ? 245  ILE A HB   1 
ATOM   3671 H HG12 . ILE A 1 230 ? 210.713 132.255 175.968 1.00 164.54 ? 245  ILE A HG12 1 
ATOM   3672 H HG13 . ILE A 1 230 ? 211.544 132.494 177.511 1.00 165.18 ? 245  ILE A HG13 1 
ATOM   3673 H HG21 . ILE A 1 230 ? 210.657 135.813 174.904 1.00 164.29 ? 245  ILE A HG21 1 
ATOM   3674 H HG22 . ILE A 1 230 ? 209.376 135.138 175.900 1.00 164.08 ? 245  ILE A HG22 1 
ATOM   3675 H HG23 . ILE A 1 230 ? 210.052 134.183 174.559 1.00 164.49 ? 245  ILE A HG23 1 
ATOM   3676 H HD11 . ILE A 1 230 ? 209.261 132.052 178.032 1.00 164.89 ? 245  ILE A HD11 1 
ATOM   3677 H HD12 . ILE A 1 230 ? 208.674 133.237 176.866 1.00 164.25 ? 245  ILE A HD12 1 
ATOM   3678 H HD13 . ILE A 1 230 ? 209.530 133.777 178.336 1.00 164.71 ? 245  ILE A HD13 1 
ATOM   3679 N N    . SER A 1 231 ? 214.416 135.524 174.494 1.00 184.64 ? 246  SER A N    1 
ATOM   3680 C CA   . SER A 1 231 ? 215.013 136.752 173.953 1.00 186.40 ? 246  SER A CA   1 
ATOM   3681 C C    . SER A 1 231 ? 215.976 136.469 172.795 1.00 187.07 ? 246  SER A C    1 
ATOM   3682 O O    . SER A 1 231 ? 216.480 135.359 172.605 1.00 188.41 ? 246  SER A O    1 
ATOM   3683 C CB   . SER A 1 231 ? 215.714 137.580 175.049 1.00 186.61 ? 246  SER A CB   1 
ATOM   3684 O OG   . SER A 1 231 ? 216.755 136.877 175.708 1.00 184.00 ? 246  SER A OG   1 
ATOM   3685 H H    . SER A 1 231 ? 214.721 134.641 174.109 1.00 184.82 ? 246  SER A H    1 
ATOM   3686 H HA   . SER A 1 231 ? 214.207 137.366 173.549 1.00 184.75 ? 246  SER A HA   1 
ATOM   3687 H HB2  . SER A 1 231 ? 216.129 138.485 174.607 1.00 185.40 ? 246  SER A HB2  1 
ATOM   3688 H HB3  . SER A 1 231 ? 214.979 137.891 175.790 1.00 184.69 ? 246  SER A HB3  1 
ATOM   3689 H HG   . SER A 1 231 ? 217.614 137.123 175.357 1.00 185.14 ? 246  SER A HG   1 
ATOM   3690 N N    . SER A 1 232 ? 216.270 137.494 171.998 1.00 185.11 ? 247  SER A N    1 
ATOM   3691 C CA   . SER A 1 232 ? 217.048 137.359 170.759 1.00 184.72 ? 247  SER A CA   1 
ATOM   3692 C C    . SER A 1 232 ? 218.493 136.886 170.962 1.00 186.11 ? 247  SER A C    1 
ATOM   3693 O O    . SER A 1 232 ? 219.045 136.225 170.081 1.00 188.35 ? 247  SER A O    1 
ATOM   3694 C CB   . SER A 1 232 ? 217.040 138.693 170.012 1.00 184.01 ? 247  SER A CB   1 
ATOM   3695 O OG   . SER A 1 232 ? 217.610 139.712 170.817 1.00 183.14 ? 247  SER A OG   1 
ATOM   3696 H H    . SER A 1 232 ? 215.863 138.398 172.192 1.00 185.12 ? 247  SER A H    1 
ATOM   3697 H HA   . SER A 1 232 ? 216.556 136.617 170.130 1.00 185.37 ? 247  SER A HA   1 
ATOM   3698 H HB2  . SER A 1 232 ? 217.607 138.592 169.086 1.00 185.40 ? 247  SER A HB2  1 
ATOM   3699 H HB3  . SER A 1 232 ? 216.012 138.959 169.763 1.00 185.24 ? 247  SER A HB3  1 
ATOM   3700 H HG   . SER A 1 232 ? 217.590 140.531 170.317 1.00 185.30 ? 247  SER A HG   1 
ATOM   3701 N N    . ASN A 1 233 ? 219.102 137.150 172.122 1.00 192.45 ? 248  ASN A N    1 
ATOM   3702 C CA   . ASN A 1 233 ? 220.438 136.647 172.453 1.00 193.36 ? 248  ASN A CA   1 
ATOM   3703 C C    . ASN A 1 233 ? 220.461 135.187 172.947 1.00 194.06 ? 248  ASN A C    1 
ATOM   3704 O O    . ASN A 1 233 ? 221.551 134.638 173.098 1.00 193.22 ? 248  ASN A O    1 
ATOM   3705 C CB   . ASN A 1 233 ? 221.146 137.597 173.438 1.00 192.57 ? 248  ASN A CB   1 
ATOM   3706 C CG   . ASN A 1 233 ? 220.629 137.492 174.861 1.00 194.46 ? 248  ASN A CG   1 
ATOM   3707 O OD1  . ASN A 1 233 ? 219.424 137.520 175.092 1.00 195.68 ? 248  ASN A OD1  1 
ATOM   3708 N ND2  . ASN A 1 233 ? 221.491 137.366 175.841 1.00 193.73 ? 248  ASN A ND2  1 
ATOM   3709 H H    . ASN A 1 233 ? 218.626 137.736 172.793 1.00 192.24 ? 248  ASN A H    1 
ATOM   3710 H HA   . ASN A 1 233 ? 221.027 136.657 171.536 1.00 192.21 ? 248  ASN A HA   1 
ATOM   3711 H HB2  . ASN A 1 233 ? 222.210 137.359 173.436 1.00 192.42 ? 248  ASN A HB2  1 
ATOM   3712 H HB3  . ASN A 1 233 ? 221.042 138.629 173.102 1.00 192.06 ? 248  ASN A HB3  1 
ATOM   3713 H HD21 . ASN A 1 233 ? 222.482 137.345 175.649 1.00 192.66 ? 248  ASN A HD21 1 
ATOM   3714 H HD22 . ASN A 1 233 ? 221.138 137.295 176.784 1.00 192.43 ? 248  ASN A HD22 1 
ATOM   3715 N N    . THR A 1 234 ? 219.310 134.544 173.203 1.00 188.85 ? 249  THR A N    1 
ATOM   3716 C CA   . THR A 1 234 ? 219.273 133.158 173.715 1.00 188.46 ? 249  THR A CA   1 
ATOM   3717 C C    . THR A 1 234 ? 218.460 132.185 172.861 1.00 188.20 ? 249  THR A C    1 
ATOM   3718 O O    . THR A 1 234 ? 218.855 131.026 172.756 1.00 186.81 ? 249  THR A O    1 
ATOM   3719 C CB   . THR A 1 234 ? 218.798 133.070 175.176 1.00 189.42 ? 249  THR A CB   1 
ATOM   3720 O OG1  . THR A 1 234 ? 217.406 133.287 175.337 1.00 188.98 ? 249  THR A OG1  1 
ATOM   3721 C CG2  . THR A 1 234 ? 219.533 134.024 176.111 1.00 189.52 ? 249  THR A CG2  1 
ATOM   3722 H H    . THR A 1 234 ? 218.436 135.039 173.093 1.00 188.10 ? 249  THR A H    1 
ATOM   3723 H HA   . THR A 1 234 ? 220.285 132.755 173.712 1.00 188.08 ? 249  THR A HA   1 
ATOM   3724 H HB   . THR A 1 234 ? 219.005 132.056 175.520 1.00 188.08 ? 249  THR A HB   1 
ATOM   3725 H HG1  . THR A 1 234 ? 216.920 132.582 174.904 1.00 187.86 ? 249  THR A HG1  1 
ATOM   3726 H HG21 . THR A 1 234 ? 219.281 133.781 177.144 1.00 188.03 ? 249  THR A HG21 1 
ATOM   3727 H HG22 . THR A 1 234 ? 220.609 133.919 175.975 1.00 188.08 ? 249  THR A HG22 1 
ATOM   3728 H HG23 . THR A 1 234 ? 219.233 135.052 175.908 1.00 188.42 ? 249  THR A HG23 1 
ATOM   3729 N N    . ASP A 1 235 ? 217.343 132.597 172.250 1.00 189.51 ? 250  ASP A N    1 
ATOM   3730 C CA   . ASP A 1 235 ? 216.479 131.673 171.486 1.00 189.00 ? 250  ASP A CA   1 
ATOM   3731 C C    . ASP A 1 235 ? 215.598 132.305 170.389 1.00 188.51 ? 250  ASP A C    1 
ATOM   3732 O O    . ASP A 1 235 ? 214.950 131.563 169.649 1.00 186.53 ? 250  ASP A O    1 
ATOM   3733 C CB   . ASP A 1 235 ? 215.597 130.872 172.463 1.00 185.79 ? 250  ASP A CB   1 
ATOM   3734 C CG   . ASP A 1 235 ? 214.722 131.736 173.377 1.00 190.40 ? 250  ASP A CG   1 
ATOM   3735 O OD1  . ASP A 1 235 ? 214.436 132.901 173.024 1.00 194.37 ? 250  ASP A OD1  1 
ATOM   3736 O OD2  . ASP A 1 235 ? 214.402 131.251 174.482 1.00 187.37 ? 250  ASP A OD2  1 
ATOM   3737 H H    . ASP A 1 235 ? 217.005 133.530 172.437 1.00 187.88 ? 250  ASP A H    1 
ATOM   3738 H HA   . ASP A 1 235 ? 217.117 130.959 170.968 1.00 187.35 ? 250  ASP A HA   1 
ATOM   3739 H HB2  . ASP A 1 235 ? 214.958 130.193 171.900 1.00 186.73 ? 250  ASP A HB2  1 
ATOM   3740 H HB3  . ASP A 1 235 ? 216.247 130.253 173.082 1.00 186.74 ? 250  ASP A HB3  1 
ATOM   3741 N N    . ASN A 1 236 ? 215.563 133.635 170.247 1.00 185.15 ? 251  ASN A N    1 
ATOM   3742 C CA   . ASN A 1 236 ? 214.628 134.351 169.360 1.00 182.91 ? 251  ASN A CA   1 
ATOM   3743 C C    . ASN A 1 236 ? 213.134 134.048 169.603 1.00 182.92 ? 251  ASN A C    1 
ATOM   3744 O O    . ASN A 1 236 ? 212.298 134.445 168.789 1.00 182.74 ? 251  ASN A O    1 
ATOM   3745 C CB   . ASN A 1 236 ? 215.022 134.172 167.874 1.00 183.07 ? 251  ASN A CB   1 
ATOM   3746 C CG   . ASN A 1 236 ? 216.119 135.110 167.421 1.00 189.00 ? 251  ASN A CG   1 
ATOM   3747 O OD1  . ASN A 1 236 ? 216.129 136.284 167.779 1.00 191.49 ? 251  ASN A OD1  1 
ATOM   3748 N ND2  . ASN A 1 236 ? 217.040 134.595 166.624 1.00 191.73 ? 251  ASN A ND2  1 
ATOM   3749 H H    . ASN A 1 236 ? 216.066 134.184 170.929 1.00 185.95 ? 251  ASN A H    1 
ATOM   3750 H HA   . ASN A 1 236 ? 214.711 135.411 169.600 1.00 185.58 ? 251  ASN A HA   1 
ATOM   3751 H HB2  . ASN A 1 236 ? 215.310 133.138 167.684 1.00 185.22 ? 251  ASN A HB2  1 
ATOM   3752 H HB3  . ASN A 1 236 ? 214.172 134.385 167.228 1.00 185.31 ? 251  ASN A HB3  1 
ATOM   3753 H HD21 . ASN A 1 236 ? 216.941 133.633 166.333 1.00 186.12 ? 251  ASN A HD21 1 
ATOM   3754 N N    . GLU A 1 237 ? 212.745 133.453 170.729 1.00 170.40 ? 252  GLU A N    1 
ATOM   3755 C CA   . GLU A 1 237 ? 211.329 133.337 171.073 1.00 170.65 ? 252  GLU A CA   1 
ATOM   3756 C C    . GLU A 1 237 ? 210.754 134.616 171.689 1.00 171.27 ? 252  GLU A C    1 
ATOM   3757 O O    . GLU A 1 237 ? 211.473 135.483 172.182 1.00 172.12 ? 252  GLU A O    1 
ATOM   3758 C CB   . GLU A 1 237 ? 211.066 132.114 171.966 1.00 172.07 ? 252  GLU A CB   1 
ATOM   3759 C CG   . GLU A 1 237 ? 210.682 130.886 171.131 1.00 170.48 ? 252  GLU A CG   1 
ATOM   3760 C CD   . GLU A 1 237 ? 209.409 131.079 170.281 1.00 173.75 ? 252  GLU A CD   1 
ATOM   3761 O OE1  . GLU A 1 237 ? 208.720 132.121 170.406 1.00 177.29 ? 252  GLU A OE1  1 
ATOM   3762 O OE2  . GLU A 1 237 ? 209.106 130.189 169.456 1.00 175.14 ? 252  GLU A OE2  1 
ATOM   3763 H H    . GLU A 1 237 ? 213.428 133.228 171.438 1.00 172.11 ? 252  GLU A H    1 
ATOM   3764 H HA   . GLU A 1 237 ? 210.785 133.206 170.139 1.00 171.32 ? 252  GLU A HA   1 
ATOM   3765 H HB2  . GLU A 1 237 ? 211.946 131.884 172.565 1.00 171.57 ? 252  GLU A HB2  1 
ATOM   3766 H HB3  . GLU A 1 237 ? 210.249 132.321 172.657 1.00 171.71 ? 252  GLU A HB3  1 
ATOM   3767 H HG2  . GLU A 1 237 ? 211.521 130.640 170.479 1.00 171.07 ? 252  GLU A HG2  1 
ATOM   3768 H HG3  . GLU A 1 237 ? 210.533 130.046 171.809 1.00 170.76 ? 252  GLU A HG3  1 
ATOM   3769 N N    . THR A 1 238 ? 209.427 134.729 171.659 1.00 151.26 ? 253  THR A N    1 
ATOM   3770 C CA   . THR A 1 238 ? 208.682 135.894 172.158 1.00 146.99 ? 253  THR A CA   1 
ATOM   3771 C C    . THR A 1 238 ? 207.365 135.484 172.799 1.00 152.53 ? 253  THR A C    1 
ATOM   3772 O O    . THR A 1 238 ? 206.741 134.503 172.395 1.00 160.21 ? 253  THR A O    1 
ATOM   3773 C CB   . THR A 1 238 ? 208.381 136.914 171.048 1.00 144.94 ? 253  THR A CB   1 
ATOM   3774 O OG1  . THR A 1 238 ? 207.621 136.333 170.010 1.00 144.79 ? 253  THR A OG1  1 
ATOM   3775 C CG2  . THR A 1 238 ? 209.637 137.501 170.417 1.00 146.82 ? 253  THR A CG2  1 
ATOM   3776 H H    . THR A 1 238 ? 208.903 133.950 171.286 1.00 152.10 ? 253  THR A H    1 
ATOM   3777 H HA   . THR A 1 238 ? 209.277 136.399 172.918 1.00 150.46 ? 253  THR A HA   1 
ATOM   3778 H HB   . THR A 1 238 ? 207.810 137.735 171.481 1.00 149.94 ? 253  THR A HB   1 
ATOM   3779 H HG1  . THR A 1 238 ? 207.624 136.971 169.293 1.00 150.05 ? 253  THR A HG1  1 
ATOM   3780 H HG21 . THR A 1 238 ? 209.364 138.311 169.739 1.00 150.55 ? 253  THR A HG21 1 
ATOM   3781 H HG22 . THR A 1 238 ? 210.281 137.905 171.197 1.00 150.42 ? 253  THR A HG22 1 
ATOM   3782 H HG23 . THR A 1 238 ? 210.180 136.736 169.863 1.00 150.93 ? 253  THR A HG23 1 
ATOM   3783 N N    . LEU A 1 239 ? 206.916 136.266 173.777 1.00 145.84 ? 254  LEU A N    1 
ATOM   3784 C CA   . LEU A 1 239 ? 205.530 136.271 174.233 1.00 142.23 ? 254  LEU A CA   1 
ATOM   3785 C C    . LEU A 1 239 ? 204.710 137.176 173.311 1.00 141.42 ? 254  LEU A C    1 
ATOM   3786 O O    . LEU A 1 239 ? 205.226 138.186 172.842 1.00 139.87 ? 254  LEU A O    1 
ATOM   3787 C CB   . LEU A 1 239 ? 205.448 136.808 175.670 1.00 139.54 ? 254  LEU A CB   1 
ATOM   3788 C CG   . LEU A 1 239 ? 206.370 136.120 176.680 1.00 145.49 ? 254  LEU A CG   1 
ATOM   3789 C CD1  . LEU A 1 239 ? 206.236 136.792 178.035 1.00 149.21 ? 254  LEU A CD1  1 
ATOM   3790 C CD2  . LEU A 1 239 ? 206.034 134.648 176.861 1.00 146.62 ? 254  LEU A CD2  1 
ATOM   3791 H H    . LEU A 1 239 ? 207.481 137.058 174.047 1.00 145.50 ? 254  LEU A H    1 
ATOM   3792 H HA   . LEU A 1 239 ? 205.119 135.262 174.204 1.00 145.50 ? 254  LEU A HA   1 
ATOM   3793 H HB2  . LEU A 1 239 ? 205.701 137.867 175.653 1.00 145.14 ? 254  LEU A HB2  1 
ATOM   3794 H HB3  . LEU A 1 239 ? 204.418 136.715 176.017 1.00 144.69 ? 254  LEU A HB3  1 
ATOM   3795 H HG   . LEU A 1 239 ? 207.407 136.219 176.360 1.00 145.70 ? 254  LEU A HG   1 
ATOM   3796 H HD11 . LEU A 1 239 ? 207.007 136.397 178.695 1.00 146.45 ? 254  LEU A HD11 1 
ATOM   3797 H HD12 . LEU A 1 239 ? 206.379 137.868 177.936 1.00 146.33 ? 254  LEU A HD12 1 
ATOM   3798 H HD13 . LEU A 1 239 ? 205.249 136.598 178.455 1.00 146.13 ? 254  LEU A HD13 1 
ATOM   3799 H HD21 . LEU A 1 239 ? 206.257 134.107 175.941 1.00 146.16 ? 254  LEU A HD21 1 
ATOM   3800 H HD22 . LEU A 1 239 ? 204.978 134.530 177.106 1.00 145.50 ? 254  LEU A HD22 1 
ATOM   3801 H HD23 . LEU A 1 239 ? 206.637 134.227 177.666 1.00 146.07 ? 254  LEU A HD23 1 
ATOM   3802 N N    . GLN A 1 240 ? 203.439 136.853 173.084 1.00 135.28 ? 255  GLN A N    1 
ATOM   3803 C CA   . GLN A 1 240 ? 202.455 137.800 172.559 1.00 136.20 ? 255  GLN A CA   1 
ATOM   3804 C C    . GLN A 1 240 ? 201.104 137.544 173.211 1.00 135.32 ? 255  GLN A C    1 
ATOM   3805 O O    . GLN A 1 240 ? 200.646 136.405 173.244 1.00 141.76 ? 255  GLN A O    1 
ATOM   3806 C CB   . GLN A 1 240 ? 202.310 137.711 171.038 1.00 135.30 ? 255  GLN A CB   1 
ATOM   3807 C CG   . GLN A 1 240 ? 203.594 138.033 170.265 1.00 137.58 ? 255  GLN A CG   1 
ATOM   3808 C CD   . GLN A 1 240 ? 203.377 138.155 168.763 1.00 141.93 ? 255  GLN A CD   1 
ATOM   3809 O OE1  . GLN A 1 240 ? 202.312 137.893 168.227 1.00 147.10 ? 255  GLN A OE1  1 
ATOM   3810 N NE2  . GLN A 1 240 ? 204.381 138.554 168.018 1.00 142.21 ? 255  GLN A NE2  1 
ATOM   3811 H H    . GLN A 1 240 ? 203.083 135.993 173.477 1.00 139.13 ? 255  GLN A H    1 
ATOM   3812 H HA   . GLN A 1 240 ? 202.762 138.817 172.804 1.00 139.32 ? 255  GLN A HA   1 
ATOM   3813 H HB2  . GLN A 1 240 ? 201.959 136.718 170.757 1.00 138.52 ? 255  GLN A HB2  1 
ATOM   3814 H HB3  . GLN A 1 240 ? 201.547 138.433 170.747 1.00 138.74 ? 255  GLN A HB3  1 
ATOM   3815 H HG2  . GLN A 1 240 ? 203.991 138.983 170.623 1.00 138.91 ? 255  GLN A HG2  1 
ATOM   3816 H HG3  . GLN A 1 240 ? 204.334 137.252 170.442 1.00 139.10 ? 255  GLN A HG3  1 
ATOM   3817 H HE21 . GLN A 1 240 ? 205.261 138.817 168.440 1.00 139.27 ? 255  GLN A HE21 1 
ATOM   3818 H HE22 . GLN A 1 240 ? 204.233 138.640 167.023 1.00 140.16 ? 255  GLN A HE22 1 
ATOM   3819 N N    . TYR A 1 241 ? 200.430 138.589 173.676 1.00 121.49 ? 256  TYR A N    1 
ATOM   3820 C CA   . TYR A 1 241 ? 199.101 138.486 174.267 1.00 119.05 ? 256  TYR A CA   1 
ATOM   3821 C C    . TYR A 1 241 ? 198.266 139.657 173.760 1.00 127.10 ? 256  TYR A C    1 
ATOM   3822 O O    . TYR A 1 241 ? 198.237 140.732 174.354 1.00 133.41 ? 256  TYR A O    1 
ATOM   3823 C CB   . TYR A 1 241 ? 199.217 138.406 175.795 1.00 122.52 ? 256  TYR A CB   1 
ATOM   3824 C CG   . TYR A 1 241 ? 197.968 137.885 176.469 1.00 125.54 ? 256  TYR A CG   1 
ATOM   3825 C CD1  . TYR A 1 241 ? 196.813 138.676 176.525 1.00 127.00 ? 256  TYR A CD1  1 
ATOM   3826 C CD2  . TYR A 1 241 ? 197.947 136.589 177.008 1.00 128.61 ? 256  TYR A CD2  1 
ATOM   3827 C CE1  . TYR A 1 241 ? 195.626 138.158 177.062 1.00 124.19 ? 256  TYR A CE1  1 
ATOM   3828 C CE2  . TYR A 1 241 ? 196.764 136.069 177.560 1.00 129.59 ? 256  TYR A CE2  1 
ATOM   3829 C CZ   . TYR A 1 241 ? 195.593 136.846 177.558 1.00 126.90 ? 256  TYR A CZ   1 
ATOM   3830 O OH   . TYR A 1 241 ? 194.419 136.330 177.999 1.00 133.83 ? 256  TYR A OH   1 
ATOM   3831 H H    . TYR A 1 241 ? 200.855 139.503 173.612 1.00 129.55 ? 256  TYR A H    1 
ATOM   3832 H HA   . TYR A 1 241 ? 198.620 137.570 173.927 1.00 127.53 ? 256  TYR A HA   1 
ATOM   3833 H HB2  . TYR A 1 241 ? 200.036 137.732 176.044 1.00 127.43 ? 256  TYR A HB2  1 
ATOM   3834 H HB3  . TYR A 1 241 ? 199.468 139.386 176.202 1.00 128.31 ? 256  TYR A HB3  1 
ATOM   3835 H HD1  . TYR A 1 241 ? 196.836 139.687 176.148 1.00 128.98 ? 256  TYR A HD1  1 
ATOM   3836 H HD2  . TYR A 1 241 ? 198.838 135.980 176.988 1.00 128.93 ? 256  TYR A HD2  1 
ATOM   3837 H HE1  . TYR A 1 241 ? 194.731 138.761 177.099 1.00 128.45 ? 256  TYR A HE1  1 
ATOM   3838 H HE2  . TYR A 1 241 ? 196.753 135.065 177.957 1.00 128.97 ? 256  TYR A HE2  1 
ATOM   3839 H HH   . TYR A 1 241 ? 194.556 135.481 178.425 1.00 128.45 ? 256  TYR A HH   1 
ATOM   3840 N N    . TRP A 1 242 ? 197.658 139.483 172.594 1.00 129.31 ? 257  TRP A N    1 
ATOM   3841 C CA   . TRP A 1 242 ? 196.868 140.505 171.928 1.00 127.65 ? 257  TRP A CA   1 
ATOM   3842 C C    . TRP A 1 242 ? 195.473 140.571 172.529 1.00 124.98 ? 257  TRP A C    1 
ATOM   3843 O O    . TRP A 1 242 ? 194.789 139.556 172.536 1.00 130.34 ? 257  TRP A O    1 
ATOM   3844 C CB   . TRP A 1 242 ? 196.769 140.144 170.449 1.00 127.21 ? 257  TRP A CB   1 
ATOM   3845 C CG   . TRP A 1 242 ? 198.057 140.073 169.711 1.00 122.75 ? 257  TRP A CG   1 
ATOM   3846 C CD1  . TRP A 1 242 ? 198.723 138.942 169.414 1.00 122.91 ? 257  TRP A CD1  1 
ATOM   3847 C CD2  . TRP A 1 242 ? 198.863 141.160 169.181 1.00 122.02 ? 257  TRP A CD2  1 
ATOM   3848 N NE1  . TRP A 1 242 ? 199.877 139.254 168.733 1.00 130.03 ? 257  TRP A NE1  1 
ATOM   3849 C CE2  . TRP A 1 242 ? 200.020 140.608 168.574 1.00 126.89 ? 257  TRP A CE2  1 
ATOM   3850 C CE3  . TRP A 1 242 ? 198.741 142.559 169.163 1.00 126.15 ? 257  TRP A CE3  1 
ATOM   3851 C CZ2  . TRP A 1 242 ? 201.017 141.392 167.992 1.00 128.28 ? 257  TRP A CZ2  1 
ATOM   3852 C CZ3  . TRP A 1 242 ? 199.726 143.359 168.563 1.00 131.46 ? 257  TRP A CZ3  1 
ATOM   3853 C CH2  . TRP A 1 242 ? 200.864 142.783 167.984 1.00 129.78 ? 257  TRP A CH2  1 
ATOM   3854 H H    . TRP A 1 242 ? 197.673 138.570 172.166 1.00 129.76 ? 257  TRP A H    1 
ATOM   3855 H HA   . TRP A 1 242 ? 197.356 141.475 172.016 1.00 129.92 ? 257  TRP A HA   1 
ATOM   3856 H HB2  . TRP A 1 242 ? 196.263 139.185 170.346 1.00 129.56 ? 257  TRP A HB2  1 
ATOM   3857 H HB3  . TRP A 1 242 ? 196.142 140.883 169.952 1.00 129.15 ? 257  TRP A HB3  1 
ATOM   3858 H HD1  . TRP A 1 242 ? 198.402 137.947 169.685 1.00 129.17 ? 257  TRP A HD1  1 
ATOM   3859 H HE1  . TRP A 1 242 ? 200.567 138.576 168.446 1.00 130.74 ? 257  TRP A HE1  1 
ATOM   3860 H HE3  . TRP A 1 242 ? 197.889 143.026 169.632 1.00 129.05 ? 257  TRP A HE3  1 
ATOM   3861 H HZ2  . TRP A 1 242 ? 201.888 140.931 167.551 1.00 129.63 ? 257  TRP A HZ2  1 
ATOM   3862 H HZ3  . TRP A 1 242 ? 199.618 144.433 168.566 1.00 130.81 ? 257  TRP A HZ3  1 
ATOM   3863 H HH2  . TRP A 1 242 ? 201.618 143.412 167.535 1.00 130.04 ? 257  TRP A HH2  1 
ATOM   3864 N N    . VAL A 1 243 ? 195.003 141.738 172.966 1.00 117.96 ? 258  VAL A N    1 
ATOM   3865 C CA   . VAL A 1 243 ? 193.621 141.927 173.447 1.00 118.95 ? 258  VAL A CA   1 
ATOM   3866 C C    . VAL A 1 243 ? 192.899 143.036 172.705 1.00 122.03 ? 258  VAL A C    1 
ATOM   3867 O O    . VAL A 1 243 ? 193.523 143.997 172.262 1.00 127.47 ? 258  VAL A O    1 
ATOM   3868 C CB   . VAL A 1 243 ? 193.537 142.197 174.948 1.00 118.89 ? 258  VAL A CB   1 
ATOM   3869 C CG1  . VAL A 1 243 ? 194.216 141.110 175.762 1.00 124.77 ? 258  VAL A CG1  1 
ATOM   3870 C CG2  . VAL A 1 243 ? 194.164 143.534 175.322 1.00 128.13 ? 258  VAL A CG2  1 
ATOM   3871 H H    . VAL A 1 243 ? 195.629 142.531 172.976 1.00 125.86 ? 258  VAL A H    1 
ATOM   3872 H HA   . VAL A 1 243 ? 193.064 141.008 173.266 1.00 125.57 ? 258  VAL A HA   1 
ATOM   3873 H HB   . VAL A 1 243 ? 192.485 142.218 175.236 1.00 124.60 ? 258  VAL A HB   1 
ATOM   3874 H HG11 . VAL A 1 243 ? 195.293 141.150 175.600 1.00 125.59 ? 258  VAL A HG11 1 
ATOM   3875 H HG12 . VAL A 1 243 ? 194.005 141.250 176.822 1.00 125.94 ? 258  VAL A HG12 1 
ATOM   3876 H HG13 . VAL A 1 243 ? 193.834 140.139 175.446 1.00 125.65 ? 258  VAL A HG13 1 
ATOM   3877 H HG21 . VAL A 1 243 ? 193.581 144.357 174.908 1.00 126.10 ? 258  VAL A HG21 1 
ATOM   3878 H HG22 . VAL A 1 243 ? 195.183 143.589 174.937 1.00 126.13 ? 258  VAL A HG22 1 
ATOM   3879 H HG23 . VAL A 1 243 ? 194.194 143.624 176.407 1.00 127.05 ? 258  VAL A HG23 1 
ATOM   3880 N N    . THR A 1 244 ? 191.581 142.930 172.584 1.00 125.34 ? 259  THR A N    1 
ATOM   3881 C CA   . THR A 1 244 ? 190.730 143.993 172.042 1.00 123.03 ? 259  THR A CA   1 
ATOM   3882 C C    . THR A 1 244 ? 189.360 143.991 172.732 1.00 119.74 ? 259  THR A C    1 
ATOM   3883 O O    . THR A 1 244 ? 188.915 142.922 173.152 1.00 130.12 ? 259  THR A O    1 
ATOM   3884 C CB   . THR A 1 244 ? 190.616 143.843 170.524 1.00 127.05 ? 259  THR A CB   1 
ATOM   3885 O OG1  . THR A 1 244 ? 190.050 144.997 169.966 1.00 132.89 ? 259  THR A OG1  1 
ATOM   3886 C CG2  . THR A 1 244 ? 189.765 142.654 170.100 1.00 125.31 ? 259  THR A CG2  1 
ATOM   3887 H H    . THR A 1 244 ? 191.132 142.085 172.907 1.00 126.62 ? 259  THR A H    1 
ATOM   3888 H HA   . THR A 1 244 ? 191.223 144.944 172.241 1.00 126.00 ? 259  THR A HA   1 
ATOM   3889 H HB   . THR A 1 244 ? 191.615 143.720 170.104 1.00 126.20 ? 259  THR A HB   1 
ATOM   3890 H HG1  . THR A 1 244 ? 190.776 145.563 169.697 1.00 127.69 ? 259  THR A HG1  1 
ATOM   3891 H HG21 . THR A 1 244 ? 189.816 142.537 169.018 1.00 126.07 ? 259  THR A HG21 1 
ATOM   3892 H HG22 . THR A 1 244 ? 190.155 141.745 170.560 1.00 125.79 ? 259  THR A HG22 1 
ATOM   3893 H HG23 . THR A 1 244 ? 188.726 142.798 170.395 1.00 125.99 ? 259  THR A HG23 1 
ATOM   3894 N N    . PRO A 1 245 ? 188.683 145.136 172.915 1.00 106.32 ? 260  PRO A N    1 
ATOM   3895 C CA   . PRO A 1 245 ? 187.400 145.190 173.601 1.00 113.04 ? 260  PRO A CA   1 
ATOM   3896 C C    . PRO A 1 245 ? 186.296 144.421 172.887 1.00 115.53 ? 260  PRO A C    1 
ATOM   3897 O O    . PRO A 1 245 ? 186.178 144.487 171.667 1.00 116.82 ? 260  PRO A O    1 
ATOM   3898 C CB   . PRO A 1 245 ? 187.028 146.668 173.683 1.00 114.85 ? 260  PRO A CB   1 
ATOM   3899 C CG   . PRO A 1 245 ? 188.368 147.375 173.583 1.00 120.76 ? 260  PRO A CG   1 
ATOM   3900 C CD   . PRO A 1 245 ? 189.147 146.480 172.636 1.00 116.95 ? 260  PRO A CD   1 
ATOM   3901 H HA   . PRO A 1 245 ? 187.527 144.800 174.611 1.00 116.69 ? 260  PRO A HA   1 
ATOM   3902 H HB2  . PRO A 1 245 ? 186.413 146.956 172.830 1.00 115.80 ? 260  PRO A HB2  1 
ATOM   3903 H HB3  . PRO A 1 245 ? 186.517 146.902 174.617 1.00 116.47 ? 260  PRO A HB3  1 
ATOM   3904 H HG2  . PRO A 1 245 ? 188.265 148.388 173.192 1.00 117.55 ? 260  PRO A HG2  1 
ATOM   3905 H HG3  . PRO A 1 245 ? 188.850 147.384 174.560 1.00 117.18 ? 260  PRO A HG3  1 
ATOM   3906 H HD2  . PRO A 1 245 ? 188.907 146.743 171.606 1.00 116.64 ? 260  PRO A HD2  1 
ATOM   3907 H HD3  . PRO A 1 245 ? 190.214 146.604 172.824 1.00 117.33 ? 260  PRO A HD3  1 
ATOM   3908 N N    . LEU A 1 246 ? 185.430 143.761 173.649 1.00 123.70 ? 261  LEU A N    1 
ATOM   3909 C CA   . LEU A 1 246 ? 184.157 143.235 173.166 1.00 122.44 ? 261  LEU A CA   1 
ATOM   3910 C C    . LEU A 1 246 ? 183.046 144.269 173.302 1.00 125.74 ? 261  LEU A C    1 
ATOM   3911 O O    . LEU A 1 246 ? 183.063 145.111 174.196 1.00 126.94 ? 261  LEU A O    1 
ATOM   3912 C CB   . LEU A 1 246 ? 183.777 141.977 173.954 1.00 124.92 ? 261  LEU A CB   1 
ATOM   3913 C CG   . LEU A 1 246 ? 184.697 140.787 173.678 1.00 124.14 ? 261  LEU A CG   1 
ATOM   3914 C CD1  . LEU A 1 246 ? 184.306 139.612 174.561 1.00 124.92 ? 261  LEU A CD1  1 
ATOM   3915 C CD2  . LEU A 1 246 ? 184.594 140.336 172.231 1.00 127.69 ? 261  LEU A CD2  1 
ATOM   3916 H H    . LEU A 1 246 ? 185.577 143.778 174.648 1.00 126.13 ? 261  LEU A H    1 
ATOM   3917 H HA   . LEU A 1 246 ? 184.240 142.986 172.108 1.00 125.15 ? 261  LEU A HA   1 
ATOM   3918 H HB2  . LEU A 1 246 ? 183.795 142.207 175.019 1.00 126.36 ? 261  LEU A HB2  1 
ATOM   3919 H HB3  . LEU A 1 246 ? 182.757 141.690 173.697 1.00 125.96 ? 261  LEU A HB3  1 
ATOM   3920 H HG   . LEU A 1 246 ? 185.729 141.065 173.893 1.00 126.08 ? 261  LEU A HG   1 
ATOM   3921 H HD11 . LEU A 1 246 ? 184.976 138.774 174.372 1.00 126.28 ? 261  LEU A HD11 1 
ATOM   3922 H HD12 . LEU A 1 246 ? 184.407 139.897 175.608 1.00 126.63 ? 261  LEU A HD12 1 
ATOM   3923 H HD13 . LEU A 1 246 ? 183.279 139.308 174.357 1.00 125.72 ? 261  LEU A HD13 1 
ATOM   3924 H HD21 . LEU A 1 246 ? 183.545 140.269 171.943 1.00 125.64 ? 261  LEU A HD21 1 
ATOM   3925 H HD22 . LEU A 1 246 ? 185.118 141.044 171.589 1.00 126.70 ? 261  LEU A HD22 1 
ATOM   3926 H HD23 . LEU A 1 246 ? 185.046 139.352 172.110 1.00 126.62 ? 261  LEU A HD23 1 
ATOM   3927 N N    . SER A 1 247 ? 182.027 144.157 172.461 1.00 134.77 ? 262  SER A N    1 
ATOM   3928 C CA   . SER A 1 247 ? 180.775 144.904 172.576 1.00 134.00 ? 262  SER A CA   1 
ATOM   3929 C C    . SER A 1 247 ? 179.636 144.104 171.949 1.00 135.02 ? 262  SER A C    1 
ATOM   3930 O O    . SER A 1 247 ? 179.877 143.138 171.227 1.00 142.03 ? 262  SER A O    1 
ATOM   3931 C CB   . SER A 1 247 ? 180.922 146.284 171.933 1.00 137.75 ? 262  SER A CB   1 
ATOM   3932 O OG   . SER A 1 247 ? 181.317 146.175 170.580 1.00 136.59 ? 262  SER A OG   1 
ATOM   3933 H H    . SER A 1 247 ? 182.077 143.466 171.725 1.00 134.75 ? 262  SER A H    1 
ATOM   3934 H HA   . SER A 1 247 ? 180.534 145.047 173.630 1.00 134.72 ? 262  SER A HA   1 
ATOM   3935 H HB2  . SER A 1 247 ? 179.973 146.817 171.990 1.00 135.41 ? 262  SER A HB2  1 
ATOM   3936 H HB3  . SER A 1 247 ? 181.670 146.859 172.480 1.00 136.06 ? 262  SER A HB3  1 
ATOM   3937 H HG   . SER A 1 247 ? 182.186 145.767 170.569 1.00 135.57 ? 262  SER A HG   1 
ATOM   3938 N N    . LYS A 1 248 ? 178.385 144.445 172.253 1.00 135.46 ? 263  LYS A N    1 
ATOM   3939 C CA   . LYS A 1 248 ? 177.211 143.743 171.727 1.00 136.02 ? 263  LYS A CA   1 
ATOM   3940 C C    . LYS A 1 248 ? 176.990 144.153 170.260 1.00 138.23 ? 263  LYS A C    1 
ATOM   3941 O O    . LYS A 1 248 ? 176.540 145.267 170.006 1.00 138.56 ? 263  LYS A O    1 
ATOM   3942 C CB   . LYS A 1 248 ? 176.025 144.058 172.657 1.00 137.63 ? 263  LYS A CB   1 
ATOM   3943 C CG   . LYS A 1 248 ? 174.849 143.076 172.575 1.00 138.83 ? 263  LYS A CG   1 
ATOM   3944 C CD   . LYS A 1 248 ? 175.206 141.687 173.126 1.00 138.49 ? 263  LYS A CD   1 
ATOM   3945 C CE   . LYS A 1 248 ? 173.999 140.742 173.195 1.00 140.66 ? 263  LYS A CE   1 
ATOM   3946 N NZ   . LYS A 1 248 ? 173.061 141.092 174.293 1.00 145.45 ? 263  LYS A NZ   1 
ATOM   3947 H H    . LYS A 1 248 ? 178.235 145.243 172.854 1.00 137.35 ? 263  LYS A H    1 
ATOM   3948 H HA   . LYS A 1 248 ? 177.412 142.671 171.755 1.00 137.38 ? 263  LYS A HA   1 
ATOM   3949 H HB2  . LYS A 1 248 ? 176.373 144.059 173.690 1.00 137.67 ? 263  LYS A HB2  1 
ATOM   3950 H HB3  . LYS A 1 248 ? 175.656 145.062 172.445 1.00 138.70 ? 263  LYS A HB3  1 
ATOM   3951 H HG2  . LYS A 1 248 ? 174.029 143.492 173.159 1.00 138.88 ? 263  LYS A HG2  1 
ATOM   3952 H HG3  . LYS A 1 248 ? 174.524 142.989 171.539 1.00 137.81 ? 263  LYS A HG3  1 
ATOM   3953 H HD2  . LYS A 1 248 ? 175.951 141.229 172.476 1.00 137.96 ? 263  LYS A HD2  1 
ATOM   3954 H HD3  . LYS A 1 248 ? 175.644 141.787 174.120 1.00 137.61 ? 263  LYS A HD3  1 
ATOM   3955 H HE2  . LYS A 1 248 ? 173.478 140.764 172.237 1.00 137.96 ? 263  LYS A HE2  1 
ATOM   3956 H HE3  . LYS A 1 248 ? 174.366 139.727 173.348 1.00 138.26 ? 263  LYS A HE3  1 
ATOM   3957 H HZ1  . LYS A 1 248 ? 172.266 140.468 174.296 1.00 139.36 ? 263  LYS A HZ1  1 
ATOM   3958 H HZ2  . LYS A 1 248 ? 172.707 142.032 174.189 1.00 139.47 ? 263  LYS A HZ2  1 
ATOM   3959 H HZ3  . LYS A 1 248 ? 173.504 141.017 175.197 1.00 138.91 ? 263  LYS A HZ3  1 
ATOM   3960 N N    . ARG A 1 249 ? 177.346 143.300 169.294 1.00 133.77 ? 264  ARG A N    1 
ATOM   3961 C CA   . ARG A 1 249 ? 177.364 143.604 167.840 1.00 126.22 ? 264  ARG A CA   1 
ATOM   3962 C C    . ARG A 1 249 ? 176.607 142.562 167.040 1.00 134.91 ? 264  ARG A C    1 
ATOM   3963 O O    . ARG A 1 249 ? 176.544 141.411 167.455 1.00 141.68 ? 264  ARG A O    1 
ATOM   3964 C CB   . ARG A 1 249 ? 178.804 143.675 167.308 1.00 121.49 ? 264  ARG A CB   1 
ATOM   3965 C CG   . ARG A 1 249 ? 179.579 144.815 167.960 1.00 121.57 ? 264  ARG A CG   1 
ATOM   3966 C CD   . ARG A 1 249 ? 181.008 144.968 167.436 1.00 126.62 ? 264  ARG A CD   1 
ATOM   3967 N NE   . ARG A 1 249 ? 181.050 145.598 166.114 1.00 134.93 ? 264  ARG A NE   1 
ATOM   3968 C CZ   . ARG A 1 249 ? 180.733 146.834 165.805 1.00 139.29 ? 264  ARG A CZ   1 
ATOM   3969 N NH1  . ARG A 1 249 ? 180.778 147.192 164.568 1.00 142.83 ? 264  ARG A NH1  1 
ATOM   3970 N NH2  . ARG A 1 249 ? 180.369 147.721 166.684 1.00 137.51 ? 264  ARG A NH2  1 
ATOM   3971 H H    . ARG A 1 249 ? 177.693 142.398 169.587 1.00 134.05 ? 264  ARG A H    1 
ATOM   3972 H HA   . ARG A 1 249 ? 176.876 144.562 167.659 1.00 132.31 ? 264  ARG A HA   1 
ATOM   3973 H HB2  . ARG A 1 249 ? 179.313 142.731 167.503 1.00 132.58 ? 264  ARG A HB2  1 
ATOM   3974 H HB3  . ARG A 1 249 ? 178.782 143.842 166.231 1.00 131.89 ? 264  ARG A HB3  1 
ATOM   3975 H HG2  . ARG A 1 249 ? 179.023 145.744 167.839 1.00 131.90 ? 264  ARG A HG2  1 
ATOM   3976 H HG3  . ARG A 1 249 ? 179.649 144.610 169.028 1.00 132.60 ? 264  ARG A HG3  1 
ATOM   3977 H HD2  . ARG A 1 249 ? 181.587 145.573 168.134 1.00 132.18 ? 264  ARG A HD2  1 
ATOM   3978 H HD3  . ARG A 1 249 ? 181.472 143.983 167.392 1.00 133.16 ? 264  ARG A HD3  1 
ATOM   3979 H HE   . ARG A 1 249 ? 181.436 145.061 165.351 1.00 134.46 ? 264  ARG A HE   1 
ATOM   3980 H HH11 . ARG A 1 249 ? 180.918 146.452 163.895 1.00 135.50 ? 264  ARG A HH11 1 
ATOM   3981 H HH12 . ARG A 1 249 ? 180.340 148.054 164.278 1.00 134.02 ? 264  ARG A HH12 1 
ATOM   3982 H HH21 . ARG A 1 249 ? 180.309 147.454 167.656 1.00 133.29 ? 264  ARG A HH21 1 
ATOM   3983 H HH22 . ARG A 1 249 ? 180.082 148.642 166.387 1.00 134.05 ? 264  ARG A HH22 1 
ATOM   3984 N N    . GLN A 1 250 ? 176.086 142.936 165.876 1.00 133.34 ? 265  GLN A N    1 
ATOM   3985 C CA   . GLN A 1 250 ? 175.473 141.991 164.946 1.00 132.48 ? 265  GLN A CA   1 
ATOM   3986 C C    . GLN A 1 250 ? 176.498 141.533 163.915 1.00 131.23 ? 265  GLN A C    1 
ATOM   3987 O O    . GLN A 1 250 ? 177.084 142.351 163.210 1.00 130.47 ? 265  GLN A O    1 
ATOM   3988 C CB   . GLN A 1 250 ? 174.269 142.634 164.258 1.00 136.10 ? 265  GLN A CB   1 
ATOM   3989 C CG   . GLN A 1 250 ? 173.544 141.632 163.343 1.00 136.22 ? 265  GLN A CG   1 
ATOM   3990 C CD   . GLN A 1 250 ? 172.256 142.212 162.772 1.00 142.60 ? 265  GLN A CD   1 
ATOM   3991 O OE1  . GLN A 1 250 ? 172.176 143.373 162.399 1.00 147.45 ? 265  GLN A OE1  1 
ATOM   3992 N NE2  . GLN A 1 250 ? 171.197 141.440 162.677 1.00 138.64 ? 265  GLN A NE2  1 
ATOM   3993 H H    . GLN A 1 250 ? 176.194 143.895 165.580 1.00 134.72 ? 265  GLN A H    1 
ATOM   3994 H HA   . GLN A 1 250 ? 175.112 141.121 165.496 1.00 134.80 ? 265  GLN A HA   1 
ATOM   3995 H HB2  . GLN A 1 250 ? 173.572 142.977 165.023 1.00 135.68 ? 265  GLN A HB2  1 
ATOM   3996 H HB3  . GLN A 1 250 ? 174.595 143.493 163.673 1.00 135.41 ? 265  GLN A HB3  1 
ATOM   3997 H HG2  . GLN A 1 250 ? 174.187 141.347 162.511 1.00 134.60 ? 265  GLN A HG2  1 
ATOM   3998 H HG3  . GLN A 1 250 ? 173.309 140.737 163.919 1.00 134.90 ? 265  GLN A HG3  1 
ATOM   3999 H HE21 . GLN A 1 250 ? 171.217 140.487 163.010 1.00 134.65 ? 265  GLN A HE21 1 
ATOM   4000 H HE22 . GLN A 1 250 ? 170.352 141.846 162.301 1.00 136.03 ? 265  GLN A HE22 1 
ATOM   4001 N N    . TYR A 1 251 ? 176.691 140.226 163.804 1.00 131.94 ? 266  TYR A N    1 
ATOM   4002 C CA   . TYR A 1 251 ? 177.584 139.595 162.840 1.00 131.76 ? 266  TYR A CA   1 
ATOM   4003 C C    . TYR A 1 251 ? 176.780 138.723 161.890 1.00 134.76 ? 266  TYR A C    1 
ATOM   4004 O O    . TYR A 1 251 ? 175.852 138.037 162.307 1.00 141.31 ? 266  TYR A O    1 
ATOM   4005 C CB   . TYR A 1 251 ? 178.607 138.707 163.552 1.00 132.14 ? 266  TYR A CB   1 
ATOM   4006 C CG   . TYR A 1 251 ? 179.907 139.356 163.968 1.00 130.08 ? 266  TYR A CG   1 
ATOM   4007 C CD1  . TYR A 1 251 ? 179.969 140.686 164.415 1.00 135.61 ? 266  TYR A CD1  1 
ATOM   4008 C CD2  . TYR A 1 251 ? 181.083 138.596 163.898 1.00 127.90 ? 266  TYR A CD2  1 
ATOM   4009 C CE1  . TYR A 1 251 ? 181.197 141.251 164.794 1.00 133.69 ? 266  TYR A CE1  1 
ATOM   4010 C CE2  . TYR A 1 251 ? 182.315 139.159 164.256 1.00 129.35 ? 266  TYR A CE2  1 
ATOM   4011 C CZ   . TYR A 1 251 ? 182.368 140.485 164.708 1.00 131.16 ? 266  TYR A CZ   1 
ATOM   4012 O OH   . TYR A 1 251 ? 183.553 141.008 165.085 1.00 138.31 ? 266  TYR A OH   1 
ATOM   4013 H H    . TYR A 1 251 ? 176.144 139.610 164.388 1.00 132.94 ? 266  TYR A H    1 
ATOM   4014 H HA   . TYR A 1 251 ? 178.114 140.347 162.258 1.00 132.74 ? 266  TYR A HA   1 
ATOM   4015 H HB2  . TYR A 1 251 ? 178.144 138.246 164.425 1.00 132.96 ? 266  TYR A HB2  1 
ATOM   4016 H HB3  . TYR A 1 251 ? 178.866 137.892 162.877 1.00 133.15 ? 266  TYR A HB3  1 
ATOM   4017 H HD1  . TYR A 1 251 ? 179.072 141.285 164.488 1.00 133.89 ? 266  TYR A HD1  1 
ATOM   4018 H HD2  . TYR A 1 251 ? 181.039 137.568 163.568 1.00 132.69 ? 266  TYR A HD2  1 
ATOM   4019 H HE1  . TYR A 1 251 ? 181.248 142.269 165.150 1.00 133.20 ? 266  TYR A HE1  1 
ATOM   4020 H HE2  . TYR A 1 251 ? 183.222 138.575 164.201 1.00 133.00 ? 266  TYR A HE2  1 
ATOM   4021 H HH   . TYR A 1 251 ? 183.463 141.810 165.605 1.00 133.31 ? 266  TYR A HH   1 
ATOM   4022 N N    . LEU A 1 252 ? 177.187 138.681 160.629 1.00 121.03 ? 267  LEU A N    1 
ATOM   4023 C CA   . LEU A 1 252 ? 176.919 137.528 159.786 1.00 115.37 ? 267  LEU A CA   1 
ATOM   4024 C C    . LEU A 1 252 ? 177.915 136.431 160.153 1.00 121.25 ? 267  LEU A C    1 
ATOM   4025 O O    . LEU A 1 252 ? 179.103 136.710 160.276 1.00 135.76 ? 267  LEU A O    1 
ATOM   4026 C CB   . LEU A 1 252 ? 177.081 137.931 158.322 1.00 114.75 ? 267  LEU A CB   1 
ATOM   4027 C CG   . LEU A 1 252 ? 176.568 136.871 157.345 1.00 119.85 ? 267  LEU A CG   1 
ATOM   4028 C CD1  . LEU A 1 252 ? 175.051 136.952 157.215 1.00 131.10 ? 267  LEU A CD1  1 
ATOM   4029 C CD2  . LEU A 1 252 ? 177.179 137.088 155.968 1.00 124.35 ? 267  LEU A CD2  1 
ATOM   4030 H H    . LEU A 1 252 ? 177.969 139.266 160.373 1.00 124.95 ? 267  LEU A H    1 
ATOM   4031 H HA   . LEU A 1 252 ? 175.902 137.179 159.960 1.00 124.29 ? 267  LEU A HA   1 
ATOM   4032 H HB2  . LEU A 1 252 ? 176.564 138.873 158.135 1.00 124.21 ? 267  LEU A HB2  1 
ATOM   4033 H HB3  . LEU A 1 252 ? 178.144 138.084 158.137 1.00 123.65 ? 267  LEU A HB3  1 
ATOM   4034 H HG   . LEU A 1 252 ? 176.848 135.873 157.685 1.00 123.79 ? 267  LEU A HG   1 
ATOM   4035 H HD11 . LEU A 1 252 ? 174.583 136.748 158.177 1.00 125.76 ? 267  LEU A HD11 1 
ATOM   4036 H HD12 . LEU A 1 252 ? 174.758 137.947 156.880 1.00 126.52 ? 267  LEU A HD12 1 
ATOM   4037 H HD13 . LEU A 1 252 ? 174.699 136.219 156.491 1.00 125.80 ? 267  LEU A HD13 1 
ATOM   4038 H HD21 . LEU A 1 252 ? 178.264 137.001 156.028 1.00 124.54 ? 267  LEU A HD21 1 
ATOM   4039 H HD22 . LEU A 1 252 ? 176.919 138.080 155.597 1.00 125.92 ? 267  LEU A HD22 1 
ATOM   4040 H HD23 . LEU A 1 252 ? 176.806 136.334 155.275 1.00 124.95 ? 267  LEU A HD23 1 
ATOM   4041 N N    . LEU A 1 253 ? 177.467 135.191 160.271 1.00 113.04 ? 268  LEU A N    1 
ATOM   4042 C CA   . LEU A 1 253 ? 178.302 134.016 160.494 1.00 109.85 ? 268  LEU A CA   1 
ATOM   4043 C C    . LEU A 1 253 ? 178.031 133.008 159.388 1.00 117.89 ? 268  LEU A C    1 
ATOM   4044 O O    . LEU A 1 253 ? 176.869 132.749 159.092 1.00 135.41 ? 268  LEU A O    1 
ATOM   4045 C CB   . LEU A 1 253 ? 177.956 133.402 161.856 1.00 113.77 ? 268  LEU A CB   1 
ATOM   4046 C CG   . LEU A 1 253 ? 178.128 134.334 163.060 1.00 121.40 ? 268  LEU A CG   1 
ATOM   4047 C CD1  . LEU A 1 253 ? 177.636 133.630 164.314 1.00 124.26 ? 268  LEU A CD1  1 
ATOM   4048 C CD2  . LEU A 1 253 ? 179.584 134.714 163.281 1.00 125.92 ? 268  LEU A CD2  1 
ATOM   4049 H H    . LEU A 1 253 ? 176.471 135.045 160.195 1.00 123.61 ? 268  LEU A H    1 
ATOM   4050 H HA   . LEU A 1 253 ? 179.359 134.280 160.472 1.00 122.01 ? 268  LEU A HA   1 
ATOM   4051 H HB2  . LEU A 1 253 ? 176.915 133.080 161.828 1.00 122.70 ? 268  LEU A HB2  1 
ATOM   4052 H HB3  . LEU A 1 253 ? 178.572 132.516 162.006 1.00 121.90 ? 268  LEU A HB3  1 
ATOM   4053 H HG   . LEU A 1 253 ? 177.539 135.240 162.924 1.00 123.18 ? 268  LEU A HG   1 
ATOM   4054 H HD11 . LEU A 1 253 ? 177.739 134.291 165.174 1.00 122.95 ? 268  LEU A HD11 1 
ATOM   4055 H HD12 . LEU A 1 253 ? 176.583 133.374 164.194 1.00 123.35 ? 268  LEU A HD12 1 
ATOM   4056 H HD13 . LEU A 1 253 ? 178.210 132.719 164.487 1.00 123.34 ? 268  LEU A HD13 1 
ATOM   4057 H HD21 . LEU A 1 253 ? 179.667 135.334 164.174 1.00 123.18 ? 268  LEU A HD21 1 
ATOM   4058 H HD22 . LEU A 1 253 ? 180.188 133.816 163.403 1.00 123.85 ? 268  LEU A HD22 1 
ATOM   4059 H HD23 . LEU A 1 253 ? 179.946 135.286 162.426 1.00 124.12 ? 268  LEU A HD23 1 
ATOM   4060 N N    . LYS A 1 254 ? 179.060 132.416 158.785 1.00 117.84 ? 269  LYS A N    1 
ATOM   4061 C CA   . LYS A 1 254 ? 178.902 131.342 157.799 1.00 118.11 ? 269  LYS A CA   1 
ATOM   4062 C C    . LYS A 1 254 ? 179.393 130.019 158.358 1.00 124.63 ? 269  LYS A C    1 
ATOM   4063 O O    . LYS A 1 254 ? 180.560 129.897 158.719 1.00 137.04 ? 269  LYS A O    1 
ATOM   4064 C CB   . LYS A 1 254 ? 179.639 131.708 156.514 1.00 112.68 ? 269  LYS A CB   1 
ATOM   4065 C CG   . LYS A 1 254 ? 179.445 130.633 155.437 1.00 116.81 ? 269  LYS A CG   1 
ATOM   4066 C CD   . LYS A 1 254 ? 180.150 131.039 154.141 1.00 124.80 ? 269  LYS A CD   1 
ATOM   4067 C CE   . LYS A 1 254 ? 180.216 129.883 153.139 1.00 128.55 ? 269  LYS A CE   1 
ATOM   4068 N NZ   . LYS A 1 254 ? 178.879 129.497 152.624 1.00 131.18 ? 269  LYS A NZ   1 
ATOM   4069 H H    . LYS A 1 254 ? 179.996 132.687 159.051 1.00 124.77 ? 269  LYS A H    1 
ATOM   4070 H HA   . LYS A 1 254 ? 177.847 131.222 157.552 1.00 124.59 ? 269  LYS A HA   1 
ATOM   4071 H HB2  . LYS A 1 254 ? 179.269 132.664 156.145 1.00 122.68 ? 269  LYS A HB2  1 
ATOM   4072 H HB3  . LYS A 1 254 ? 180.703 131.810 156.731 1.00 123.47 ? 269  LYS A HB3  1 
ATOM   4073 H HG2  . LYS A 1 254 ? 179.875 129.693 155.784 1.00 123.20 ? 269  LYS A HG2  1 
ATOM   4074 H HG3  . LYS A 1 254 ? 178.381 130.491 155.253 1.00 123.54 ? 269  LYS A HG3  1 
ATOM   4075 H HD2  . LYS A 1 254 ? 179.643 131.894 153.695 1.00 124.78 ? 269  LYS A HD2  1 
ATOM   4076 H HD3  . LYS A 1 254 ? 181.173 131.333 154.375 1.00 123.91 ? 269  LYS A HD3  1 
ATOM   4077 H HE2  . LYS A 1 254 ? 180.850 130.190 152.308 1.00 124.73 ? 269  LYS A HE2  1 
ATOM   4078 H HE3  . LYS A 1 254 ? 180.697 129.030 153.618 1.00 124.79 ? 269  LYS A HE3  1 
ATOM   4079 H HZ1  . LYS A 1 254 ? 178.963 128.762 151.937 1.00 125.53 ? 269  LYS A HZ1  1 
ATOM   4080 H HZ2  . LYS A 1 254 ? 178.281 129.156 153.362 1.00 124.85 ? 269  LYS A HZ2  1 
ATOM   4081 H HZ3  . LYS A 1 254 ? 178.425 130.278 152.173 1.00 125.13 ? 269  LYS A HZ3  1 
ATOM   4082 N N    . PHE A 1 255 ? 178.527 129.022 158.366 1.00 118.89 ? 270  PHE A N    1 
ATOM   4083 C CA   . PHE A 1 255 ? 178.824 127.676 158.829 1.00 115.62 ? 270  PHE A CA   1 
ATOM   4084 C C    . PHE A 1 255 ? 178.976 126.746 157.635 1.00 121.89 ? 270  PHE A C    1 
ATOM   4085 O O    . PHE A 1 255 ? 178.134 126.770 156.739 1.00 128.43 ? 270  PHE A O    1 
ATOM   4086 C CB   . PHE A 1 255 ? 177.685 127.194 159.719 1.00 116.69 ? 270  PHE A CB   1 
ATOM   4087 C CG   . PHE A 1 255 ? 177.481 128.001 160.977 1.00 114.34 ? 270  PHE A CG   1 
ATOM   4088 C CD1  . PHE A 1 255 ? 176.693 129.162 160.952 1.00 116.37 ? 270  PHE A CD1  1 
ATOM   4089 C CD2  . PHE A 1 255 ? 178.038 127.565 162.186 1.00 120.61 ? 270  PHE A CD2  1 
ATOM   4090 C CE1  . PHE A 1 255 ? 176.481 129.890 162.131 1.00 119.49 ? 270  PHE A CE1  1 
ATOM   4091 C CE2  . PHE A 1 255 ? 177.814 128.286 163.368 1.00 123.61 ? 270  PHE A CE2  1 
ATOM   4092 C CZ   . PHE A 1 255 ? 177.041 129.455 163.339 1.00 120.84 ? 270  PHE A CZ   1 
ATOM   4093 H H    . PHE A 1 255 ? 177.602 129.192 157.998 1.00 124.02 ? 270  PHE A H    1 
ATOM   4094 H HA   . PHE A 1 255 ? 179.746 127.666 159.411 1.00 122.51 ? 270  PHE A HA   1 
ATOM   4095 H HB2  . PHE A 1 255 ? 176.756 127.200 159.148 1.00 123.23 ? 270  PHE A HB2  1 
ATOM   4096 H HB3  . PHE A 1 255 ? 177.885 126.159 159.999 1.00 122.55 ? 270  PHE A HB3  1 
ATOM   4097 H HD1  . PHE A 1 255 ? 176.245 129.496 160.028 1.00 123.23 ? 270  PHE A HD1  1 
ATOM   4098 H HD2  . PHE A 1 255 ? 178.633 126.664 162.215 1.00 122.13 ? 270  PHE A HD2  1 
ATOM   4099 H HE1  . PHE A 1 255 ? 175.878 130.786 162.113 1.00 122.80 ? 270  PHE A HE1  1 
ATOM   4100 H HE2  . PHE A 1 255 ? 178.242 127.945 164.298 1.00 122.73 ? 270  PHE A HE2  1 
ATOM   4101 H HZ   . PHE A 1 255 ? 176.875 130.016 164.245 1.00 122.61 ? 270  PHE A HZ   1 
ATOM   4102 N N    . ASP A 1 256 ? 180.023 125.930 157.590 1.00 134.67 ? 271  ASP A N    1 
ATOM   4103 C CA   . ASP A 1 256 ? 180.201 124.964 156.505 1.00 137.89 ? 271  ASP A CA   1 
ATOM   4104 C C    . ASP A 1 256 ? 179.338 123.702 156.673 1.00 144.29 ? 271  ASP A C    1 
ATOM   4105 O O    . ASP A 1 256 ? 178.543 123.570 157.602 1.00 149.32 ? 271  ASP A O    1 
ATOM   4106 C CB   . ASP A 1 256 ? 181.687 124.642 156.325 1.00 137.73 ? 271  ASP A CB   1 
ATOM   4107 C CG   . ASP A 1 256 ? 182.313 123.748 157.401 1.00 146.51 ? 271  ASP A CG   1 
ATOM   4108 O OD1  . ASP A 1 256 ? 181.595 123.314 158.330 1.00 149.08 ? 271  ASP A OD1  1 
ATOM   4109 O OD2  . ASP A 1 256 ? 183.514 123.431 157.240 1.00 148.08 ? 271  ASP A OD2  1 
ATOM   4110 H H    . ASP A 1 256 ? 180.679 125.927 158.357 1.00 140.58 ? 271  ASP A H    1 
ATOM   4111 H HA   . ASP A 1 256 ? 179.883 125.436 155.575 1.00 141.34 ? 271  ASP A HA   1 
ATOM   4112 H HB2  . ASP A 1 256 ? 181.806 124.150 155.360 1.00 141.09 ? 271  ASP A HB2  1 
ATOM   4113 H HB3  . ASP A 1 256 ? 182.237 125.581 156.266 1.00 140.74 ? 271  ASP A HB3  1 
ATOM   4114 N N    . ASN A 1 257 ? 179.463 122.740 155.761 1.00 143.09 ? 272  ASN A N    1 
ATOM   4115 C CA   . ASN A 1 257 ? 178.709 121.486 155.801 1.00 139.45 ? 272  ASN A CA   1 
ATOM   4116 C C    . ASN A 1 257 ? 179.143 120.507 156.912 1.00 133.35 ? 272  ASN A C    1 
ATOM   4117 O O    . ASN A 1 257 ? 178.629 119.391 156.948 1.00 133.96 ? 272  ASN A O    1 
ATOM   4118 C CB   . ASN A 1 257 ? 178.748 120.838 154.411 1.00 140.79 ? 272  ASN A CB   1 
ATOM   4119 C CG   . ASN A 1 257 ? 180.155 120.461 154.008 1.00 145.16 ? 272  ASN A CG   1 
ATOM   4120 O OD1  . ASN A 1 257 ? 180.937 121.297 153.586 1.00 145.70 ? 272  ASN A OD1  1 
ATOM   4121 N ND2  . ASN A 1 257 ? 180.526 119.212 154.141 1.00 149.57 ? 272  ASN A ND2  1 
ATOM   4122 H H    . ASN A 1 257 ? 180.122 122.866 155.005 1.00 141.65 ? 272  ASN A H    1 
ATOM   4123 H HA   . ASN A 1 257 ? 177.669 121.726 156.019 1.00 141.58 ? 272  ASN A HA   1 
ATOM   4124 H HB2  . ASN A 1 257 ? 178.112 119.952 154.399 1.00 141.52 ? 272  ASN A HB2  1 
ATOM   4125 H HB3  . ASN A 1 257 ? 178.356 121.536 153.671 1.00 141.30 ? 272  ASN A HB3  1 
ATOM   4126 H HD21 . ASN A 1 257 ? 179.884 118.527 154.513 1.00 142.61 ? 272  ASN A HD21 1 
ATOM   4127 H HD22 . ASN A 1 257 ? 181.465 118.959 153.868 1.00 142.72 ? 272  ASN A HD22 1 
ATOM   4128 N N    . ARG A 1 258 ? 180.041 120.888 157.830 1.00 138.41 ? 273  ARG A N    1 
ATOM   4129 C CA   . ARG A 1 258 ? 180.325 120.144 159.074 1.00 143.76 ? 273  ARG A CA   1 
ATOM   4130 C C    . ARG A 1 258 ? 180.193 121.004 160.333 1.00 143.90 ? 273  ARG A C    1 
ATOM   4131 O O    . ARG A 1 258 ? 180.619 120.595 161.409 1.00 142.47 ? 273  ARG A O    1 
ATOM   4132 C CB   . ARG A 1 258 ? 181.649 119.367 158.976 1.00 142.81 ? 273  ARG A CB   1 
ATOM   4133 C CG   . ARG A 1 258 ? 182.905 120.245 159.040 1.00 146.18 ? 273  ARG A CG   1 
ATOM   4134 C CD   . ARG A 1 258 ? 184.159 119.429 158.723 1.00 149.04 ? 273  ARG A CD   1 
ATOM   4135 N NE   . ARG A 1 258 ? 185.329 120.315 158.593 1.00 154.94 ? 273  ARG A NE   1 
ATOM   4136 C CZ   . ARG A 1 258 ? 186.259 120.555 159.497 1.00 156.74 ? 273  ARG A CZ   1 
ATOM   4137 N NH1  . ARG A 1 258 ? 187.213 121.401 159.243 1.00 153.73 ? 273  ARG A NH1  1 
ATOM   4138 N NH2  . ARG A 1 258 ? 186.272 119.973 160.661 1.00 157.94 ? 273  ARG A NH2  1 
ATOM   4139 H H    . ARG A 1 258 ? 180.463 121.801 157.739 1.00 145.91 ? 273  ARG A H    1 
ATOM   4140 H HA   . ARG A 1 258 ? 179.545 119.391 159.194 1.00 146.18 ? 273  ARG A HA   1 
ATOM   4141 H HB2  . ARG A 1 258 ? 181.693 118.644 159.790 1.00 145.86 ? 273  ARG A HB2  1 
ATOM   4142 H HB3  . ARG A 1 258 ? 181.651 118.808 158.040 1.00 145.66 ? 273  ARG A HB3  1 
ATOM   4143 H HG2  . ARG A 1 258 ? 182.817 121.028 158.288 1.00 146.64 ? 273  ARG A HG2  1 
ATOM   4144 H HG3  . ARG A 1 258 ? 183.000 120.697 160.028 1.00 146.41 ? 273  ARG A HG3  1 
ATOM   4145 H HD2  . ARG A 1 258 ? 184.311 118.677 159.497 1.00 146.53 ? 273  ARG A HD2  1 
ATOM   4146 H HD3  . ARG A 1 258 ? 184.010 118.910 157.777 1.00 146.47 ? 273  ARG A HD3  1 
ATOM   4147 H HE   . ARG A 1 258 ? 185.401 120.846 157.737 1.00 146.75 ? 273  ARG A HE   1 
ATOM   4148 H HH11 . ARG A 1 258 ? 187.238 121.879 158.354 1.00 147.15 ? 273  ARG A HH11 1 
ATOM   4149 H HH12 . ARG A 1 258 ? 187.931 121.578 159.931 1.00 147.41 ? 273  ARG A HH12 1 
ATOM   4150 H HH21 . ARG A 1 258 ? 185.543 119.310 160.887 1.00 147.82 ? 273  ARG A HH21 1 
ATOM   4151 H HH22 . ARG A 1 258 ? 187.003 120.178 161.327 1.00 147.71 ? 273  ARG A HH22 1 
ATOM   4152 N N    . GLY A 1 259 ? 179.566 122.172 160.222 1.00 128.54 ? 274  GLY A N    1 
ATOM   4153 C CA   . GLY A 1 259 ? 179.194 123.016 161.352 1.00 125.69 ? 274  GLY A CA   1 
ATOM   4154 C C    . GLY A 1 259 ? 180.312 123.893 161.904 1.00 127.95 ? 274  GLY A C    1 
ATOM   4155 O O    . GLY A 1 259 ? 180.144 124.463 162.977 1.00 129.01 ? 274  GLY A O    1 
ATOM   4156 H H    . GLY A 1 259 ? 179.297 122.480 159.299 1.00 131.22 ? 274  GLY A H    1 
ATOM   4157 H HA2  . GLY A 1 259 ? 178.395 123.681 161.025 1.00 129.99 ? 274  GLY A HA2  1 
ATOM   4158 H HA3  . GLY A 1 259 ? 178.811 122.394 162.161 1.00 129.42 ? 274  GLY A HA3  1 
ATOM   4159 N N    . VAL A 1 260 ? 181.442 124.028 161.215 1.00 130.70 ? 275  VAL A N    1 
ATOM   4160 C CA   . VAL A 1 260 ? 182.518 124.942 161.619 1.00 129.90 ? 275  VAL A CA   1 
ATOM   4161 C C    . VAL A 1 260 ? 182.226 126.346 161.101 1.00 134.78 ? 275  VAL A C    1 
ATOM   4162 O O    . VAL A 1 260 ? 181.849 126.499 159.943 1.00 142.21 ? 275  VAL A O    1 
ATOM   4163 C CB   . VAL A 1 260 ? 183.868 124.432 161.098 1.00 128.96 ? 275  VAL A CB   1 
ATOM   4164 C CG1  . VAL A 1 260 ? 185.009 125.428 161.315 1.00 134.65 ? 275  VAL A CG1  1 
ATOM   4165 C CG2  . VAL A 1 260 ? 184.256 123.141 161.823 1.00 129.04 ? 275  VAL A CG2  1 
ATOM   4166 H H    . VAL A 1 260 ? 181.499 123.610 160.297 1.00 133.20 ? 275  VAL A H    1 
ATOM   4167 H HA   . VAL A 1 260 ? 182.573 124.984 162.707 1.00 132.70 ? 275  VAL A HA   1 
ATOM   4168 H HB   . VAL A 1 260 ? 183.794 124.228 160.030 1.00 132.87 ? 275  VAL A HB   1 
ATOM   4169 H HG11 . VAL A 1 260 ? 185.954 124.976 161.013 1.00 133.29 ? 275  VAL A HG11 1 
ATOM   4170 H HG12 . VAL A 1 260 ? 185.069 125.712 162.365 1.00 133.32 ? 275  VAL A HG12 1 
ATOM   4171 H HG13 . VAL A 1 260 ? 184.856 126.316 160.702 1.00 133.46 ? 275  VAL A HG13 1 
ATOM   4172 H HG21 . VAL A 1 260 ? 183.495 122.377 161.664 1.00 132.58 ? 275  VAL A HG21 1 
ATOM   4173 H HG22 . VAL A 1 260 ? 185.205 122.771 161.436 1.00 132.36 ? 275  VAL A HG22 1 
ATOM   4174 H HG23 . VAL A 1 260 ? 184.352 123.329 162.892 1.00 133.24 ? 275  VAL A HG23 1 
ATOM   4175 N N    . ILE A 1 261 ? 182.420 127.389 161.913 1.00 123.84 ? 276  ILE A N    1 
ATOM   4176 C CA   . ILE A 1 261 ? 182.335 128.775 161.433 1.00 118.77 ? 276  ILE A CA   1 
ATOM   4177 C C    . ILE A 1 261 ? 183.573 129.064 160.592 1.00 118.39 ? 276  ILE A C    1 
ATOM   4178 O O    . ILE A 1 261 ? 184.669 129.163 161.135 1.00 125.53 ? 276  ILE A O    1 
ATOM   4179 C CB   . ILE A 1 261 ? 182.208 129.782 162.592 1.00 116.51 ? 276  ILE A CB   1 
ATOM   4180 C CG1  . ILE A 1 261 ? 180.896 129.564 163.356 1.00 122.62 ? 276  ILE A CG1  1 
ATOM   4181 C CG2  . ILE A 1 261 ? 182.266 131.219 162.056 1.00 123.85 ? 276  ILE A CG2  1 
ATOM   4182 C CD1  . ILE A 1 261 ? 180.778 130.381 164.645 1.00 119.77 ? 276  ILE A CD1  1 
ATOM   4183 H H    . ILE A 1 261 ? 182.749 127.220 162.853 1.00 124.45 ? 276  ILE A H    1 
ATOM   4184 H HA   . ILE A 1 261 ? 181.453 128.881 160.802 1.00 124.40 ? 276  ILE A HA   1 
ATOM   4185 H HB   . ILE A 1 261 ? 183.037 129.634 163.283 1.00 123.89 ? 276  ILE A HB   1 
ATOM   4186 H HG12 . ILE A 1 261 ? 180.058 129.810 162.705 1.00 124.48 ? 276  ILE A HG12 1 
ATOM   4187 H HG13 . ILE A 1 261 ? 180.812 128.514 163.635 1.00 124.61 ? 276  ILE A HG13 1 
ATOM   4188 H HG21 . ILE A 1 261 ? 182.184 131.935 162.875 1.00 124.45 ? 276  ILE A HG21 1 
ATOM   4189 H HG22 . ILE A 1 261 ? 183.217 131.417 161.562 1.00 124.42 ? 276  ILE A HG22 1 
ATOM   4190 H HG23 . ILE A 1 261 ? 181.452 131.389 161.351 1.00 124.88 ? 276  ILE A HG23 1 
ATOM   4191 H HD11 . ILE A 1 261 ? 179.878 130.078 165.179 1.00 124.41 ? 276  ILE A HD11 1 
ATOM   4192 H HD12 . ILE A 1 261 ? 181.643 130.199 165.283 1.00 123.99 ? 276  ILE A HD12 1 
ATOM   4193 H HD13 . ILE A 1 261 ? 180.700 131.446 164.424 1.00 122.91 ? 276  ILE A HD13 1 
ATOM   4194 N N    . THR A 1 262 ? 183.434 129.200 159.278 1.00 125.09 ? 277  THR A N    1 
ATOM   4195 C CA   . THR A 1 262 ? 184.582 129.463 158.395 1.00 129.54 ? 277  THR A CA   1 
ATOM   4196 C C    . THR A 1 262 ? 184.795 130.941 158.117 1.00 133.94 ? 277  THR A C    1 
ATOM   4197 O O    . THR A 1 262 ? 185.920 131.348 157.853 1.00 142.23 ? 277  THR A O    1 
ATOM   4198 C CB   . THR A 1 262 ? 184.451 128.741 157.055 1.00 132.03 ? 277  THR A CB   1 
ATOM   4199 O OG1  . THR A 1 262 ? 183.316 129.178 156.355 1.00 131.79 ? 277  THR A OG1  1 
ATOM   4200 C CG2  . THR A 1 262 ? 184.347 127.235 157.236 1.00 131.77 ? 277  THR A CG2  1 
ATOM   4201 H H    . THR A 1 262 ? 182.516 129.093 158.869 1.00 131.12 ? 277  THR A H    1 
ATOM   4202 H HA   . THR A 1 262 ? 185.494 129.094 158.862 1.00 130.90 ? 277  THR A HA   1 
ATOM   4203 H HB   . THR A 1 262 ? 185.334 128.952 156.453 1.00 132.08 ? 277  THR A HB   1 
ATOM   4204 H HG1  . THR A 1 262 ? 183.564 129.976 155.882 1.00 131.30 ? 277  THR A HG1  1 
ATOM   4205 H HG21 . THR A 1 262 ? 184.352 126.753 156.258 1.00 131.83 ? 277  THR A HG21 1 
ATOM   4206 H HG22 . THR A 1 262 ? 185.201 126.876 157.810 1.00 131.31 ? 277  THR A HG22 1 
ATOM   4207 H HG23 . THR A 1 262 ? 183.427 126.979 157.762 1.00 131.18 ? 277  THR A HG23 1 
ATOM   4208 N N    . ASN A 1 263 ? 183.744 131.758 158.161 1.00 119.63 ? 278  ASN A N    1 
ATOM   4209 C CA   . ASN A 1 263 ? 183.800 133.180 157.840 1.00 116.18 ? 278  ASN A CA   1 
ATOM   4210 C C    . ASN A 1 263 ? 182.802 133.966 158.678 1.00 111.60 ? 278  ASN A C    1 
ATOM   4211 O O    . ASN A 1 263 ? 181.797 133.427 159.129 1.00 123.51 ? 278  ASN A O    1 
ATOM   4212 C CB   . ASN A 1 263 ? 183.517 133.411 156.350 1.00 121.83 ? 278  ASN A CB   1 
ATOM   4213 C CG   . ASN A 1 263 ? 184.419 132.614 155.438 1.00 128.56 ? 278  ASN A CG   1 
ATOM   4214 O OD1  . ASN A 1 263 ? 184.134 131.475 155.095 1.00 132.27 ? 278  ASN A OD1  1 
ATOM   4215 N ND2  . ASN A 1 263 ? 185.523 133.180 155.024 1.00 126.34 ? 278  ASN A ND2  1 
ATOM   4216 H H    . ASN A 1 263 ? 182.845 131.371 158.415 1.00 124.06 ? 278  ASN A H    1 
ATOM   4217 H HA   . ASN A 1 263 ? 184.796 133.559 158.070 1.00 123.13 ? 278  ASN A HA   1 
ATOM   4218 H HB2  . ASN A 1 263 ? 182.485 133.140 156.128 1.00 123.31 ? 278  ASN A HB2  1 
ATOM   4219 H HB3  . ASN A 1 263 ? 183.633 134.470 156.119 1.00 123.36 ? 278  ASN A HB3  1 
ATOM   4220 H HD21 . ASN A 1 263 ? 185.800 134.071 155.410 1.00 124.46 ? 278  ASN A HD21 1 
ATOM   4221 H HD22 . ASN A 1 263 ? 186.139 132.654 154.421 1.00 123.83 ? 278  ASN A HD22 1 
ATOM   4222 N N    . ALA A 1 264 ? 183.049 135.256 158.841 1.00 98.29  ? 279  ALA A N    1 
ATOM   4223 C CA   . ALA A 1 264 ? 182.142 136.159 159.516 1.00 104.79 ? 279  ALA A CA   1 
ATOM   4224 C C    . ALA A 1 264 ? 182.228 137.560 158.928 1.00 117.80 ? 279  ALA A C    1 
ATOM   4225 O O    . ALA A 1 264 ? 183.196 137.896 158.251 1.00 124.69 ? 279  ALA A O    1 
ATOM   4226 C CB   . ALA A 1 264 ? 182.450 136.149 161.005 1.00 112.74 ? 279  ALA A CB   1 
ATOM   4227 H H    . ALA A 1 264 ? 183.867 135.666 158.416 1.00 117.26 ? 279  ALA A H    1 
ATOM   4228 H HA   . ALA A 1 264 ? 181.123 135.803 159.368 1.00 117.26 ? 279  ALA A HA   1 
ATOM   4229 H HB1  . ALA A 1 264 ? 182.364 135.126 161.374 1.00 117.51 ? 279  ALA A HB1  1 
ATOM   4230 H HB2  . ALA A 1 264 ? 181.734 136.781 161.529 1.00 117.60 ? 279  ALA A HB2  1 
ATOM   4231 H HB3  . ALA A 1 264 ? 183.458 136.520 161.188 1.00 118.64 ? 279  ALA A HB3  1 
ATOM   4232 N N    . VAL A 1 265 ? 181.222 138.389 159.174 1.00 126.44 ? 280  VAL A N    1 
ATOM   4233 C CA   . VAL A 1 265 ? 181.233 139.799 158.785 1.00 120.18 ? 280  VAL A CA   1 
ATOM   4234 C C    . VAL A 1 265 ? 180.631 140.625 159.905 1.00 123.80 ? 280  VAL A C    1 
ATOM   4235 O O    . VAL A 1 265 ? 179.488 140.410 160.287 1.00 131.54 ? 280  VAL A O    1 
ATOM   4236 C CB   . VAL A 1 265 ? 180.461 140.028 157.475 1.00 117.95 ? 280  VAL A CB   1 
ATOM   4237 C CG1  . VAL A 1 265 ? 180.497 141.496 157.047 1.00 127.38 ? 280  VAL A CG1  1 
ATOM   4238 C CG2  . VAL A 1 265 ? 181.016 139.195 156.318 1.00 122.00 ? 280  VAL A CG2  1 
ATOM   4239 H H    . VAL A 1 265 ? 180.439 138.040 159.708 1.00 126.04 ? 280  VAL A H    1 
ATOM   4240 H HA   . VAL A 1 265 ? 182.260 140.130 158.631 1.00 124.68 ? 280  VAL A HA   1 
ATOM   4241 H HB   . VAL A 1 265 ? 179.415 139.755 157.616 1.00 124.09 ? 280  VAL A HB   1 
ATOM   4242 H HG11 . VAL A 1 265 ? 179.981 141.616 156.093 1.00 126.44 ? 280  VAL A HG11 1 
ATOM   4243 H HG12 . VAL A 1 265 ? 179.987 142.118 157.782 1.00 125.87 ? 280  VAL A HG12 1 
ATOM   4244 H HG13 . VAL A 1 265 ? 181.528 141.830 156.939 1.00 125.37 ? 280  VAL A HG13 1 
ATOM   4245 H HG21 . VAL A 1 265 ? 180.885 138.132 156.522 1.00 124.94 ? 280  VAL A HG21 1 
ATOM   4246 H HG22 . VAL A 1 265 ? 180.477 139.429 155.400 1.00 125.26 ? 280  VAL A HG22 1 
ATOM   4247 H HG23 . VAL A 1 265 ? 182.076 139.411 156.178 1.00 125.84 ? 280  VAL A HG23 1 
ATOM   4248 N N    . ASP A 1 266 ? 181.368 141.603 160.409 1.00 132.47 ? 281  ASP A N    1 
ATOM   4249 C CA   . ASP A 1 266 ? 180.819 142.626 161.292 1.00 135.70 ? 281  ASP A CA   1 
ATOM   4250 C C    . ASP A 1 266 ? 179.952 143.562 160.446 1.00 141.18 ? 281  ASP A C    1 
ATOM   4251 O O    . ASP A 1 266 ? 180.462 144.225 159.543 1.00 148.02 ? 281  ASP A O    1 
ATOM   4252 C CB   . ASP A 1 266 ? 181.997 143.342 161.950 1.00 138.87 ? 281  ASP A CB   1 
ATOM   4253 C CG   . ASP A 1 266 ? 181.600 144.411 162.960 1.00 144.32 ? 281  ASP A CG   1 
ATOM   4254 O OD1  . ASP A 1 266 ? 180.511 145.014 162.847 1.00 149.15 ? 281  ASP A OD1  1 
ATOM   4255 O OD2  . ASP A 1 266 ? 182.412 144.694 163.863 1.00 148.83 ? 281  ASP A OD2  1 
ATOM   4256 H H    . ASP A 1 266 ? 182.301 141.742 160.048 1.00 138.31 ? 281  ASP A H    1 
ATOM   4257 H HA   . ASP A 1 266 ? 180.206 142.164 162.065 1.00 138.35 ? 281  ASP A HA   1 
ATOM   4258 H HB2  . ASP A 1 266 ? 182.610 142.597 162.457 1.00 139.41 ? 281  ASP A HB2  1 
ATOM   4259 H HB3  . ASP A 1 266 ? 182.607 143.807 161.175 1.00 139.29 ? 281  ASP A HB3  1 
ATOM   4260 N N    . CYS A 1 267 ? 178.643 143.603 160.683 1.00 138.04 ? 282  CYS A N    1 
ATOM   4261 C CA   . CYS A 1 267 ? 177.721 144.319 159.801 1.00 139.57 ? 282  CYS A CA   1 
ATOM   4262 C C    . CYS A 1 267 ? 177.819 145.852 159.875 1.00 139.39 ? 282  CYS A C    1 
ATOM   4263 O O    . CYS A 1 267 ? 177.106 146.537 159.141 1.00 142.80 ? 282  CYS A O    1 
ATOM   4264 C CB   . CYS A 1 267 ? 176.295 143.863 160.098 1.00 144.79 ? 282  CYS A CB   1 
ATOM   4265 S SG   . CYS A 1 267 ? 176.062 142.206 159.405 1.00 152.16 ? 282  CYS A SG   1 
ATOM   4266 H H    . CYS A 1 267 ? 178.262 143.072 161.452 1.00 140.47 ? 282  CYS A H    1 
ATOM   4267 H HA   . CYS A 1 267 ? 177.950 144.057 158.768 1.00 141.11 ? 282  CYS A HA   1 
ATOM   4268 H HB2  . CYS A 1 267 ? 176.110 143.863 161.173 1.00 141.65 ? 282  CYS A HB2  1 
ATOM   4269 H HB3  . CYS A 1 267 ? 175.584 144.539 159.621 1.00 141.83 ? 282  CYS A HB3  1 
ATOM   4270 H HG   . CYS A 1 267 ? 177.031 141.608 160.105 1.00 142.36 ? 282  CYS A HG   1 
ATOM   4271 N N    . SER A 1 268 ? 178.665 146.420 160.733 1.00 138.80 ? 283  SER A N    1 
ATOM   4272 C CA   . SER A 1 268 ? 178.840 147.875 160.832 1.00 141.88 ? 283  SER A CA   1 
ATOM   4273 C C    . SER A 1 268 ? 180.310 148.248 161.037 1.00 140.02 ? 283  SER A C    1 
ATOM   4274 O O    . SER A 1 268 ? 181.163 147.993 160.176 1.00 115.44 ? 283  SER A O    1 
ATOM   4275 C CB   . SER A 1 268 ? 177.982 148.443 161.966 1.00 143.32 ? 283  SER A CB   1 
ATOM   4276 O OG   . SER A 1 268 ? 178.386 147.927 163.218 1.00 146.24 ? 283  SER A OG   1 
ATOM   4277 H H    . SER A 1 268 ? 179.253 145.822 161.296 1.00 139.08 ? 283  SER A H    1 
ATOM   4278 H HA   . SER A 1 268 ? 178.524 148.355 159.907 1.00 138.62 ? 283  SER A HA   1 
ATOM   4279 H HB2  . SER A 1 268 ? 178.084 149.528 161.976 1.00 139.09 ? 283  SER A HB2  1 
ATOM   4280 H HB3  . SER A 1 268 ? 176.935 148.198 161.787 1.00 139.05 ? 283  SER A HB3  1 
ATOM   4281 H HG   . SER A 1 268 ? 178.075 147.021 163.268 1.00 139.48 ? 283  SER A HG   1 
HETATM 4282 C C1   . NAG B 2 .   ? 194.425 141.408 203.333 1.00 157.89 ? 1    NAG B C1   1 
HETATM 4283 C C2   . NAG B 2 .   ? 195.335 140.745 204.387 1.00 155.61 ? 1    NAG B C2   1 
HETATM 4284 C C3   . NAG B 2 .   ? 195.961 141.839 205.267 1.00 160.90 ? 1    NAG B C3   1 
HETATM 4285 C C4   . NAG B 2 .   ? 196.611 142.952 204.440 1.00 162.85 ? 1    NAG B C4   1 
HETATM 4286 C C5   . NAG B 2 .   ? 195.650 143.528 203.405 1.00 161.83 ? 1    NAG B C5   1 
HETATM 4287 C C6   . NAG B 2 .   ? 196.318 144.553 202.484 1.00 164.27 ? 1    NAG B C6   1 
HETATM 4288 C C7   . NAG B 2 .   ? 194.695 138.503 205.150 1.00 161.09 ? 1    NAG B C7   1 
HETATM 4289 C C8   . NAG B 2 .   ? 193.734 137.678 206.015 1.00 163.10 ? 1    NAG B C8   1 
HETATM 4290 N N2   . NAG B 2 .   ? 194.552 139.820 205.213 1.00 157.11 ? 1    NAG B N2   1 
HETATM 4291 O O3   . NAG B 2 .   ? 196.968 141.271 206.143 1.00 162.75 ? 1    NAG B O3   1 
HETATM 4292 O O4   . NAG B 2 .   ? 196.985 144.027 205.367 1.00 167.04 ? 1    NAG B O4   1 
HETATM 4293 O O5   . NAG B 2 .   ? 195.175 142.405 202.588 1.00 159.44 ? 1    NAG B O5   1 
HETATM 4294 O O6   . NAG B 2 .   ? 195.369 145.022 201.513 1.00 166.24 ? 1    NAG B O6   1 
HETATM 4295 O O7   . NAG B 2 .   ? 195.539 137.975 204.432 1.00 159.32 ? 1    NAG B O7   1 
HETATM 4296 H H1   . NAG B 2 .   ? 193.579 141.889 203.825 1.00 160.83 ? 1    NAG B H1   1 
HETATM 4297 H H2   . NAG B 2 .   ? 196.136 140.214 203.872 1.00 160.47 ? 1    NAG B H2   1 
HETATM 4298 H H3   . NAG B 2 .   ? 195.181 142.285 205.884 1.00 161.58 ? 1    NAG B H3   1 
HETATM 4299 H H4   . NAG B 2 .   ? 197.495 142.562 203.935 1.00 161.38 ? 1    NAG B H4   1 
HETATM 4300 H H5   . NAG B 2 .   ? 194.801 143.990 203.909 1.00 161.36 ? 1    NAG B H5   1 
HETATM 4301 H H61  . NAG B 2 .   ? 196.687 145.403 203.059 1.00 161.51 ? 1    NAG B H61  1 
HETATM 4302 H H62  . NAG B 2 .   ? 197.161 144.097 201.964 1.00 161.58 ? 1    NAG B H62  1 
HETATM 4303 H H81  . NAG B 2 .   ? 193.950 136.615 205.901 1.00 161.65 ? 1    NAG B H81  1 
HETATM 4304 H H82  . NAG B 2 .   ? 193.852 137.955 207.062 1.00 161.93 ? 1    NAG B H82  1 
HETATM 4305 H H83  . NAG B 2 .   ? 192.706 137.868 205.705 1.00 161.10 ? 1    NAG B H83  1 
HETATM 4306 H HN2  . NAG B 2 .   ? 193.848 140.206 205.825 1.00 160.93 ? 1    NAG B HN2  1 
HETATM 4307 H HO3  . NAG B 2 .   ? 197.545 141.977 206.448 1.00 161.78 ? 1    NAG B HO3  1 
HETATM 4308 H HO6  . NAG B 2 .   ? 195.863 145.459 200.816 1.00 161.90 ? 1    NAG B HO6  1 
HETATM 4309 C C1   . NAG B 2 .   ? 198.412 144.327 205.412 1.00 183.69 ? 2    NAG B C1   1 
HETATM 4310 C C2   . NAG B 2 .   ? 198.641 145.645 206.178 1.00 182.97 ? 2    NAG B C2   1 
HETATM 4311 C C3   . NAG B 2 .   ? 200.144 145.906 206.336 1.00 182.81 ? 2    NAG B C3   1 
HETATM 4312 C C4   . NAG B 2 .   ? 200.849 144.706 206.966 1.00 185.13 ? 2    NAG B C4   1 
HETATM 4313 C C5   . NAG B 2 .   ? 200.573 143.422 206.184 1.00 185.63 ? 2    NAG B C5   1 
HETATM 4314 C C6   . NAG B 2 .   ? 201.199 142.174 206.817 1.00 184.79 ? 2    NAG B C6   1 
HETATM 4315 C C7   . NAG B 2 .   ? 196.838 147.265 205.824 1.00 184.63 ? 2    NAG B C7   1 
HETATM 4316 C C8   . NAG B 2 .   ? 196.306 148.408 204.950 1.00 180.66 ? 2    NAG B C8   1 
HETATM 4317 N N2   . NAG B 2 .   ? 198.010 146.754 205.462 1.00 182.77 ? 2    NAG B N2   1 
HETATM 4318 O O3   . NAG B 2 .   ? 200.379 147.073 207.168 1.00 182.94 ? 2    NAG B O3   1 
HETATM 4319 O O4   . NAG B 2 .   ? 202.295 144.970 206.915 1.00 188.10 ? 2    NAG B O4   1 
HETATM 4320 O O5   . NAG B 2 .   ? 199.111 143.232 206.083 1.00 185.25 ? 2    NAG B O5   1 
HETATM 4321 O O6   . NAG B 2 .   ? 200.717 142.019 208.162 1.00 182.33 ? 2    NAG B O6   1 
HETATM 4322 O O7   . NAG B 2 .   ? 196.215 146.843 206.794 1.00 187.04 ? 2    NAG B O7   1 
HETATM 4323 H H1   . NAG B 2 .   ? 198.786 144.426 204.393 1.00 182.42 ? 2    NAG B H1   1 
HETATM 4324 H H2   . NAG B 2 .   ? 198.201 145.545 207.170 1.00 182.83 ? 2    NAG B H2   1 
HETATM 4325 H H3   . NAG B 2 .   ? 200.579 146.091 205.354 1.00 183.06 ? 2    NAG B H3   1 
HETATM 4326 H H4   . NAG B 2 .   ? 200.515 144.594 207.997 1.00 182.97 ? 2    NAG B H4   1 
HETATM 4327 H H5   . NAG B 2 .   ? 200.974 143.531 205.177 1.00 183.01 ? 2    NAG B H5   1 
HETATM 4328 H H61  . NAG B 2 .   ? 202.286 142.257 206.828 1.00 183.30 ? 2    NAG B H61  1 
HETATM 4329 H H62  . NAG B 2 .   ? 200.930 141.291 206.238 1.00 182.82 ? 2    NAG B H62  1 
HETATM 4330 H H81  . NAG B 2 .   ? 196.152 148.049 203.932 1.00 182.06 ? 2    NAG B H81  1 
HETATM 4331 H H82  . NAG B 2 .   ? 195.357 148.769 205.348 1.00 182.70 ? 2    NAG B H82  1 
HETATM 4332 H H83  . NAG B 2 .   ? 197.023 149.228 204.939 1.00 182.61 ? 2    NAG B H83  1 
HETATM 4333 H HN2  . NAG B 2 .   ? 198.494 147.157 204.672 1.00 182.44 ? 2    NAG B HN2  1 
HETATM 4334 H HO3  . NAG B 2 .   ? 201.285 147.047 207.483 1.00 182.99 ? 2    NAG B HO3  1 
HETATM 4335 H HO6  . NAG B 2 .   ? 200.975 141.153 208.485 1.00 182.87 ? 2    NAG B HO6  1 
HETATM 4336 C C1   . BMA B 2 .   ? 202.927 145.026 208.230 1.00 219.10 ? 3    BMA B C1   1 
HETATM 4337 C C2   . BMA B 2 .   ? 204.456 145.047 208.051 1.00 219.68 ? 3    BMA B C2   1 
HETATM 4338 C C3   . BMA B 2 .   ? 205.121 145.151 209.424 1.00 221.06 ? 3    BMA B C3   1 
HETATM 4339 C C4   . BMA B 2 .   ? 204.629 146.390 210.187 1.00 221.55 ? 3    BMA B C4   1 
HETATM 4340 C C5   . BMA B 2 .   ? 203.096 146.403 210.290 1.00 218.82 ? 3    BMA B C5   1 
HETATM 4341 C C6   . BMA B 2 .   ? 202.547 147.691 210.904 1.00 218.13 ? 3    BMA B C6   1 
HETATM 4342 O O2   . BMA B 2 .   ? 204.844 146.184 207.237 1.00 218.15 ? 3    BMA B O2   1 
HETATM 4343 O O3   . BMA B 2 .   ? 206.591 145.216 209.245 1.00 223.17 ? 3    BMA B O3   1 
HETATM 4344 O O4   . BMA B 2 .   ? 205.184 146.367 211.522 1.00 221.00 ? 3    BMA B O4   1 
HETATM 4345 O O5   . BMA B 2 .   ? 202.502 146.235 208.945 1.00 218.89 ? 3    BMA B O5   1 
HETATM 4346 O O6   . BMA B 2 .   ? 202.946 148.855 210.091 1.00 220.74 ? 3    BMA B O6   1 
HETATM 4347 H H1   . BMA B 2 .   ? 202.639 144.144 208.801 1.00 217.83 ? 3    BMA B H1   1 
HETATM 4348 H H2   . BMA B 2 .   ? 204.776 144.130 207.556 1.00 218.40 ? 3    BMA B H2   1 
HETATM 4349 H H3   . BMA B 2 .   ? 204.859 144.262 209.997 1.00 218.59 ? 3    BMA B H3   1 
HETATM 4350 H H4   . BMA B 2 .   ? 204.974 147.287 209.672 1.00 219.11 ? 3    BMA B H4   1 
HETATM 4351 H H5   . BMA B 2 .   ? 202.774 145.565 210.908 1.00 218.03 ? 3    BMA B H5   1 
HETATM 4352 H H61  . BMA B 2 .   ? 201.458 147.648 210.955 1.00 217.98 ? 3    BMA B H61  1 
HETATM 4353 H H62  . BMA B 2 .   ? 202.925 147.796 211.921 1.00 218.49 ? 3    BMA B H62  1 
HETATM 4354 H HO2  . BMA B 2 .   ? 205.788 146.150 207.065 1.00 218.42 ? 3    BMA B HO2  1 
HETATM 4355 H HO4  . BMA B 2 .   ? 205.788 147.108 211.614 1.00 218.97 ? 3    BMA B HO4  1 
HETATM 4356 C C1   . MAN B 2 .   ? 207.274 144.056 209.816 1.00 232.26 ? 4    MAN B C1   1 
HETATM 4357 C C2   . MAN B 2 .   ? 208.777 144.356 209.998 1.00 231.39 ? 4    MAN B C2   1 
HETATM 4358 C C3   . MAN B 2 .   ? 209.522 144.394 208.656 1.00 231.65 ? 4    MAN B C3   1 
HETATM 4359 C C4   . MAN B 2 .   ? 209.264 143.122 207.821 1.00 232.32 ? 4    MAN B C4   1 
HETATM 4360 C C5   . MAN B 2 .   ? 207.749 142.904 207.639 1.00 231.80 ? 4    MAN B C5   1 
HETATM 4361 C C6   . MAN B 2 .   ? 207.405 141.589 206.921 1.00 228.75 ? 4    MAN B C6   1 
HETATM 4362 O O2   . MAN B 2 .   ? 209.388 143.323 210.826 1.00 228.45 ? 4    MAN B O2   1 
HETATM 4363 O O3   . MAN B 2 .   ? 210.934 144.529 208.960 1.00 229.29 ? 4    MAN B O3   1 
HETATM 4364 O O4   . MAN B 2 .   ? 209.880 143.263 206.509 1.00 229.40 ? 4    MAN B O4   1 
HETATM 4365 O O5   . MAN B 2 .   ? 207.074 142.877 208.958 1.00 233.08 ? 4    MAN B O5   1 
HETATM 4366 O O6   . MAN B 2 .   ? 207.914 141.617 205.571 1.00 229.22 ? 4    MAN B O6   1 
HETATM 4367 H H1   . MAN B 2 .   ? 206.851 143.852 210.799 1.00 229.25 ? 4    MAN B H1   1 
HETATM 4368 H H2   . MAN B 2 .   ? 208.891 145.316 210.502 1.00 229.31 ? 4    MAN B H2   1 
HETATM 4369 H H3   . MAN B 2 .   ? 209.199 145.269 208.090 1.00 229.41 ? 4    MAN B H3   1 
HETATM 4370 H H4   . MAN B 2 .   ? 209.694 142.254 208.320 1.00 229.72 ? 4    MAN B H4   1 
HETATM 4371 H H5   . MAN B 2 .   ? 207.337 143.732 207.062 1.00 229.36 ? 4    MAN B H5   1 
HETATM 4372 H H61  . MAN B 2 .   ? 207.833 140.741 207.456 1.00 229.17 ? 4    MAN B H61  1 
HETATM 4373 H H62  . MAN B 2 .   ? 206.322 141.463 206.889 1.00 229.04 ? 4    MAN B H62  1 
HETATM 4374 H HO2  . MAN B 2 .   ? 209.026 143.365 211.715 1.00 228.97 ? 4    MAN B HO2  1 
HETATM 4375 H HO3  . MAN B 2 .   ? 211.106 143.950 209.707 1.00 229.20 ? 4    MAN B HO3  1 
HETATM 4376 H HO4  . MAN B 2 .   ? 209.445 142.625 205.939 1.00 229.21 ? 4    MAN B HO4  1 
HETATM 4377 H HO6  . MAN B 2 .   ? 207.551 140.869 205.091 1.00 229.32 ? 4    MAN B HO6  1 
HETATM 4378 C C1   . MAN B 2 .   ? 203.193 150.041 210.911 1.00 221.78 ? 5    MAN B C1   1 
HETATM 4379 C C2   . MAN B 2 .   ? 203.059 151.328 210.062 1.00 221.35 ? 5    MAN B C2   1 
HETATM 4380 C C3   . MAN B 2 .   ? 204.257 151.524 209.122 1.00 222.55 ? 5    MAN B C3   1 
HETATM 4381 C C4   . MAN B 2 .   ? 205.593 151.428 209.874 1.00 223.53 ? 5    MAN B C4   1 
HETATM 4382 C C5   . MAN B 2 .   ? 205.669 150.067 210.574 1.00 224.91 ? 5    MAN B C5   1 
HETATM 4383 C C6   . MAN B 2 .   ? 206.972 149.826 211.346 1.00 222.22 ? 5    MAN B C6   1 
HETATM 4384 O O2   . MAN B 2 .   ? 202.982 152.493 210.934 1.00 220.04 ? 5    MAN B O2   1 
HETATM 4385 O O3   . MAN B 2 .   ? 204.149 152.831 208.501 1.00 218.36 ? 5    MAN B O3   1 
HETATM 4386 O O4   . MAN B 2 .   ? 206.663 151.548 208.904 1.00 218.97 ? 5    MAN B O4   1 
HETATM 4387 O O5   . MAN B 2 .   ? 204.529 149.947 211.521 1.00 224.03 ? 5    MAN B O5   1 
HETATM 4388 O O6   . MAN B 2 .   ? 207.003 148.457 211.817 1.00 223.26 ? 5    MAN B O6   1 
HETATM 4389 H H1   . MAN B 2 .   ? 202.445 150.078 211.702 1.00 220.60 ? 5    MAN B H1   1 
HETATM 4390 H H2   . MAN B 2 .   ? 202.142 151.276 209.475 1.00 220.64 ? 5    MAN B H2   1 
HETATM 4391 H H3   . MAN B 2 .   ? 204.228 150.764 208.341 1.00 221.13 ? 5    MAN B H3   1 
HETATM 4392 H H4   . MAN B 2 .   ? 205.682 152.232 210.605 1.00 221.15 ? 5    MAN B H4   1 
HETATM 4393 H H5   . MAN B 2 .   ? 205.579 149.291 209.813 1.00 221.53 ? 5    MAN B H5   1 
HETATM 4394 H H61  . MAN B 2 .   ? 207.835 149.995 210.703 1.00 220.85 ? 5    MAN B H61  1 
HETATM 4395 H H62  . MAN B 2 .   ? 207.037 150.505 212.196 1.00 220.86 ? 5    MAN B H62  1 
HETATM 4396 H HO2  . MAN B 2 .   ? 202.186 152.443 211.469 1.00 220.55 ? 5    MAN B HO2  1 
HETATM 4397 H HO3  . MAN B 2 .   ? 203.775 153.413 209.167 1.00 220.75 ? 5    MAN B HO3  1 
HETATM 4398 H HO4  . MAN B 2 .   ? 206.440 152.286 208.333 1.00 220.43 ? 5    MAN B HO4  1 
HETATM 4399 H HO6  . MAN B 2 .   ? 207.786 148.359 212.365 1.00 221.01 ? 5    MAN B HO6  1 
HETATM 4400 C C1   . NAG C 3 .   ? 195.213 122.260 188.834 1.00 171.46 ? 1    NAG C C1   1 
HETATM 4401 C C2   . NAG C 3 .   ? 195.260 121.205 189.952 1.00 171.82 ? 1    NAG C C2   1 
HETATM 4402 C C3   . NAG C 3 .   ? 196.281 121.614 191.027 1.00 172.91 ? 1    NAG C C3   1 
HETATM 4403 C C4   . NAG C 3 .   ? 197.635 121.959 190.392 1.00 173.26 ? 1    NAG C C4   1 
HETATM 4404 C C5   . NAG C 3 .   ? 197.489 122.958 189.243 1.00 173.47 ? 1    NAG C C5   1 
HETATM 4405 C C6   . NAG C 3 .   ? 198.805 123.276 188.535 1.00 172.92 ? 1    NAG C C6   1 
HETATM 4406 C C7   . NAG C 3 .   ? 193.162 121.849 191.100 1.00 173.27 ? 1    NAG C C7   1 
HETATM 4407 C C8   . NAG C 3 .   ? 191.774 121.371 191.543 1.00 170.11 ? 1    NAG C C8   1 
HETATM 4408 N N2   . NAG C 3 .   ? 193.922 120.944 190.491 1.00 173.52 ? 1    NAG C N2   1 
HETATM 4409 O O3   . NAG C 3 .   ? 196.465 120.530 191.976 1.00 174.07 ? 1    NAG C O3   1 
HETATM 4410 O O4   . NAG C 3 .   ? 198.464 122.586 191.432 1.00 174.58 ? 1    NAG C O4   1 
HETATM 4411 O O5   . NAG C 3 .   ? 196.537 122.414 188.260 1.00 173.66 ? 1    NAG C O5   1 
HETATM 4412 O O6   . NAG C 3 .   ? 199.396 122.054 188.057 1.00 171.65 ? 1    NAG C O6   1 
HETATM 4413 O O7   . NAG C 3 .   ? 193.542 123.000 191.286 1.00 171.59 ? 1    NAG C O7   1 
HETATM 4414 H H1   . NAG C 3 .   ? 194.894 123.222 189.235 1.00 170.61 ? 1    NAG C H1   1 
HETATM 4415 H H2   . NAG C 3 .   ? 195.600 120.270 189.508 1.00 170.76 ? 1    NAG C H2   1 
HETATM 4416 H H3   . NAG C 3 .   ? 195.931 122.493 191.567 1.00 171.25 ? 1    NAG C H3   1 
HETATM 4417 H H4   . NAG C 3 .   ? 198.104 121.044 190.029 1.00 171.36 ? 1    NAG C H4   1 
HETATM 4418 H H5   . NAG C 3 .   ? 197.078 123.886 189.643 1.00 171.29 ? 1    NAG C H5   1 
HETATM 4419 H H61  . NAG C 3 .   ? 199.496 123.769 189.219 1.00 171.19 ? 1    NAG C H61  1 
HETATM 4420 H H62  . NAG C 3 .   ? 198.624 123.941 187.690 1.00 170.81 ? 1    NAG C H62  1 
HETATM 4421 H H81  . NAG C 3 .   ? 191.188 121.088 190.669 1.00 170.69 ? 1    NAG C H81  1 
HETATM 4422 H H82  . NAG C 3 .   ? 191.258 122.171 192.074 1.00 170.70 ? 1    NAG C H82  1 
HETATM 4423 H H83  . NAG C 3 .   ? 191.874 120.511 192.205 1.00 170.93 ? 1    NAG C H83  1 
HETATM 4424 H HN2  . NAG C 3 .   ? 193.579 119.998 190.412 1.00 170.97 ? 1    NAG C HN2  1 
HETATM 4425 H HO3  . NAG C 3 .   ? 197.313 120.642 192.410 1.00 171.89 ? 1    NAG C HO3  1 
HETATM 4426 H HO6  . NAG C 3 .   ? 200.222 122.257 187.611 1.00 171.19 ? 1    NAG C HO6  1 
HETATM 4427 C C1   . NAG C 3 .   ? 199.628 121.794 191.834 1.00 192.23 ? 2    NAG C C1   1 
HETATM 4428 C C2   . NAG C 3 .   ? 200.522 122.642 192.763 1.00 192.17 ? 2    NAG C C2   1 
HETATM 4429 C C3   . NAG C 3 .   ? 201.707 121.811 193.285 1.00 194.20 ? 2    NAG C C3   1 
HETATM 4430 C C4   . NAG C 3 .   ? 201.192 120.557 193.999 1.00 195.03 ? 2    NAG C C4   1 
HETATM 4431 C C5   . NAG C 3 .   ? 200.266 119.734 193.088 1.00 192.93 ? 2    NAG C C5   1 
HETATM 4432 C C6   . NAG C 3 .   ? 199.624 118.536 193.803 1.00 190.97 ? 2    NAG C C6   1 
HETATM 4433 C C7   . NAG C 3 .   ? 201.666 123.974 191.018 1.00 190.07 ? 2    NAG C C7   1 
HETATM 4434 C C8   . NAG C 3 .   ? 201.984 125.390 190.523 1.00 187.85 ? 2    NAG C C8   1 
HETATM 4435 N N2   . NAG C 3 .   ? 200.959 123.896 192.140 1.00 190.21 ? 2    NAG C N2   1 
HETATM 4436 O O3   . NAG C 3 .   ? 202.508 122.587 194.222 1.00 189.76 ? 2    NAG C O3   1 
HETATM 4437 O O4   . NAG C 3 .   ? 202.349 119.764 194.349 1.00 188.98 ? 2    NAG C O4   1 
HETATM 4438 O O5   . NAG C 3 .   ? 199.182 120.604 192.564 1.00 195.35 ? 2    NAG C O5   1 
HETATM 4439 O O6   . NAG C 3 .   ? 198.737 118.997 194.842 1.00 191.10 ? 2    NAG C O6   1 
HETATM 4440 O O7   . NAG C 3 .   ? 202.049 122.971 190.423 1.00 190.16 ? 2    NAG C O7   1 
HETATM 4441 H H1   . NAG C 3 .   ? 200.177 121.486 190.943 1.00 189.31 ? 2    NAG C H1   1 
HETATM 4442 H H2   . NAG C 3 .   ? 199.915 122.929 193.622 1.00 189.76 ? 2    NAG C H2   1 
HETATM 4443 H H3   . NAG C 3 .   ? 202.341 121.510 192.451 1.00 190.04 ? 2    NAG C H3   1 
HETATM 4444 H H4   . NAG C 3 .   ? 200.666 120.845 194.908 1.00 190.30 ? 2    NAG C H4   1 
HETATM 4445 H H5   . NAG C 3 .   ? 200.842 119.361 192.241 1.00 189.57 ? 2    NAG C H5   1 
HETATM 4446 H H61  . NAG C 3 .   ? 199.053 117.948 193.086 1.00 189.74 ? 2    NAG C H61  1 
HETATM 4447 H H62  . NAG C 3 .   ? 200.391 117.893 194.237 1.00 189.72 ? 2    NAG C H62  1 
HETATM 4448 H H81  . NAG C 3 .   ? 202.560 125.923 191.280 1.00 189.35 ? 2    NAG C H81  1 
HETATM 4449 H H82  . NAG C 3 .   ? 202.564 125.340 189.601 1.00 188.80 ? 2    NAG C H82  1 
HETATM 4450 H H83  . NAG C 3 .   ? 201.054 125.927 190.334 1.00 188.77 ? 2    NAG C H83  1 
HETATM 4451 H HN2  . NAG C 3 .   ? 200.616 124.750 192.556 1.00 189.62 ? 2    NAG C HN2  1 
HETATM 4452 H HO3  . NAG C 3 .   ? 202.762 123.415 193.807 1.00 189.42 ? 2    NAG C HO3  1 
HETATM 4453 H HO4  . NAG C 3 .   ? 202.967 120.360 194.778 1.00 189.34 ? 2    NAG C HO4  1 
HETATM 4454 H HO6  . NAG C 3 .   ? 198.329 118.232 195.253 1.00 189.90 ? 2    NAG C HO6  1 
HETATM 4455 C C1   . NAG D 4 .   ? 208.582 147.087 201.108 1.00 185.94 ? 1401 NAG A C1   1 
HETATM 4456 C C2   . NAG D 4 .   ? 208.798 148.515 201.649 1.00 186.63 ? 1401 NAG A C2   1 
HETATM 4457 C C3   . NAG D 4 .   ? 210.299 148.778 201.808 1.00 187.38 ? 1401 NAG A C3   1 
HETATM 4458 C C4   . NAG D 4 .   ? 210.885 147.762 202.797 1.00 187.96 ? 1401 NAG A C4   1 
HETATM 4459 C C5   . NAG D 4 .   ? 210.653 146.318 202.321 1.00 185.85 ? 1401 NAG A C5   1 
HETATM 4460 C C6   . NAG D 4 .   ? 211.049 145.270 203.370 1.00 183.70 ? 1401 NAG A C6   1 
HETATM 4461 C C7   . NAG D 4 .   ? 206.944 149.941 200.927 1.00 186.52 ? 1401 NAG A C7   1 
HETATM 4462 C C8   . NAG D 4 .   ? 206.459 150.999 199.928 1.00 183.49 ? 1401 NAG A C8   1 
HETATM 4463 N N2   . NAG D 4 .   ? 208.188 149.504 200.758 1.00 185.13 ? 1401 NAG A N2   1 
HETATM 4464 O O3   . NAG D 4 .   ? 210.540 150.122 202.314 1.00 187.84 ? 1401 NAG A O3   1 
HETATM 4465 O O4   . NAG D 4 .   ? 212.303 148.019 202.874 1.00 185.17 ? 1401 NAG A O4   1 
HETATM 4466 O O5   . NAG D 4 .   ? 209.223 146.108 201.985 1.00 186.12 ? 1401 NAG A O5   1 
HETATM 4467 O O6   . NAG D 4 .   ? 210.110 145.316 204.462 1.00 182.57 ? 1401 NAG A O6   1 
HETATM 4468 O O7   . NAG D 4 .   ? 206.238 149.522 201.843 1.00 188.13 ? 1401 NAG A O7   1 
HETATM 4469 H H1   . NAG D 4 .   ? 208.984 146.990 200.100 1.00 184.16 ? 1401 NAG A H1   1 
HETATM 4470 H H2   . NAG D 4 .   ? 208.337 148.592 202.634 1.00 184.92 ? 1401 NAG A H2   1 
HETATM 4471 H H3   . NAG D 4 .   ? 210.788 148.676 200.839 1.00 184.47 ? 1401 NAG A H3   1 
HETATM 4472 H H4   . NAG D 4 .   ? 210.440 147.912 203.780 1.00 184.87 ? 1401 NAG A H4   1 
HETATM 4473 H H5   . NAG D 4 .   ? 211.243 146.153 201.419 1.00 184.47 ? 1401 NAG A H5   1 
HETATM 4474 H H61  . NAG D 4 .   ? 211.023 144.275 202.926 1.00 184.60 ? 1401 NAG A H61  1 
HETATM 4475 H H62  . NAG D 4 .   ? 212.056 145.452 203.744 1.00 184.04 ? 1401 NAG A H62  1 
HETATM 4476 H H81  . NAG D 4 .   ? 207.065 151.900 200.026 1.00 184.24 ? 1401 NAG A H81  1 
HETATM 4477 H H82  . NAG D 4 .   ? 206.549 150.614 198.912 1.00 184.02 ? 1401 NAG A H82  1 
HETATM 4478 H H83  . NAG D 4 .   ? 205.417 151.248 200.127 1.00 184.45 ? 1401 NAG A H83  1 
HETATM 4479 H HN2  . NAG D 4 .   ? 208.689 149.783 199.927 1.00 184.30 ? 1401 NAG A HN2  1 
HETATM 4480 H HO3  . NAG D 4 .   ? 210.085 150.758 201.758 1.00 184.68 ? 1401 NAG A HO3  1 
HETATM 4481 H HO4  . NAG D 4 .   ? 212.401 148.968 202.987 1.00 184.61 ? 1401 NAG A HO4  1 
HETATM 4482 H HO6  . NAG D 4 .   ? 210.307 144.623 205.095 1.00 184.12 ? 1401 NAG A HO6  1 
HETATM 4483 C C1   . NAG E 4 .   ? 175.762 123.775 150.491 1.00 181.18 ? 1402 NAG A C1   1 
HETATM 4484 C C2   . NAG E 4 .   ? 175.435 122.575 149.576 1.00 181.89 ? 1402 NAG A C2   1 
HETATM 4485 C C3   . NAG E 4 .   ? 175.609 122.997 148.108 1.00 184.29 ? 1402 NAG A C3   1 
HETATM 4486 C C4   . NAG E 4 .   ? 174.749 124.225 147.779 1.00 184.87 ? 1402 NAG A C4   1 
HETATM 4487 C C5   . NAG E 4 .   ? 175.073 125.385 148.737 1.00 183.79 ? 1402 NAG A C5   1 
HETATM 4488 C C6   . NAG E 4 .   ? 174.182 126.621 148.555 1.00 182.27 ? 1402 NAG A C6   1 
HETATM 4489 C C7   . NAG E 4 .   ? 176.063 120.576 150.854 1.00 176.78 ? 1402 NAG A C7   1 
HETATM 4490 C C8   . NAG E 4 .   ? 177.083 119.443 151.026 1.00 173.79 ? 1402 NAG A C8   1 
HETATM 4491 N N2   . NAG E 4 .   ? 176.315 121.449 149.888 1.00 180.18 ? 1402 NAG A N2   1 
HETATM 4492 O O3   . NAG E 4 .   ? 175.239 121.914 147.211 1.00 181.86 ? 1402 NAG A O3   1 
HETATM 4493 O O4   . NAG E 4 .   ? 175.063 124.614 146.417 1.00 178.07 ? 1402 NAG A O4   1 
HETATM 4494 O O5   . NAG E 4 .   ? 174.926 124.915 150.131 1.00 181.94 ? 1402 NAG A O5   1 
HETATM 4495 O O6   . NAG E 4 .   ? 172.807 126.281 148.821 1.00 182.45 ? 1402 NAG A O6   1 
HETATM 4496 O O7   . NAG E 4 .   ? 175.081 120.693 151.586 1.00 174.50 ? 1402 NAG A O7   1 
HETATM 4497 H H1   . NAG E 4 .   ? 176.811 124.056 150.394 1.00 177.94 ? 1402 NAG A H1   1 
HETATM 4498 H H2   . NAG E 4 .   ? 174.400 122.273 149.739 1.00 177.89 ? 1402 NAG A H2   1 
HETATM 4499 H H3   . NAG E 4 .   ? 176.656 123.243 147.935 1.00 179.01 ? 1402 NAG A H3   1 
HETATM 4500 H H4   . NAG E 4 .   ? 173.694 123.961 147.844 1.00 178.66 ? 1402 NAG A H4   1 
HETATM 4501 H H5   . NAG E 4 .   ? 176.110 125.687 148.586 1.00 178.29 ? 1402 NAG A H5   1 
HETATM 4502 H H61  . NAG E 4 .   ? 174.494 127.402 149.248 1.00 178.35 ? 1402 NAG A H61  1 
HETATM 4503 H H62  . NAG E 4 .   ? 174.270 127.013 147.542 1.00 178.83 ? 1402 NAG A H62  1 
HETATM 4504 H H81  . NAG E 4 .   ? 176.787 118.800 151.855 1.00 177.38 ? 1402 NAG A H81  1 
HETATM 4505 H H82  . NAG E 4 .   ? 178.066 119.862 151.235 1.00 177.16 ? 1402 NAG A H82  1 
HETATM 4506 H H83  . NAG E 4 .   ? 177.130 118.849 150.112 1.00 178.05 ? 1402 NAG A H83  1 
HETATM 4507 H HN2  . NAG E 4 .   ? 177.136 121.323 149.313 1.00 178.29 ? 1402 NAG A HN2  1 
HETATM 4508 H HO3  . NAG E 4 .   ? 175.259 122.263 146.317 1.00 178.27 ? 1402 NAG A HO3  1 
HETATM 4509 H HO4  . NAG E 4 .   ? 174.365 125.182 146.082 1.00 177.87 ? 1402 NAG A HO4  1 
HETATM 4510 H HO6  . NAG E 4 .   ? 172.289 127.089 148.829 1.00 178.71 ? 1402 NAG A HO6  1 
HETATM 4511 C C1   . NAG F 4 .   ? 213.950 133.179 196.293 1.00 199.50 ? 1403 NAG A C1   1 
HETATM 4512 C C2   . NAG F 4 .   ? 214.753 134.268 197.042 1.00 200.57 ? 1403 NAG A C2   1 
HETATM 4513 C C3   . NAG F 4 .   ? 215.958 133.619 197.739 1.00 200.44 ? 1403 NAG A C3   1 
HETATM 4514 C C4   . NAG F 4 .   ? 215.501 132.502 198.684 1.00 199.21 ? 1403 NAG A C4   1 
HETATM 4515 C C5   . NAG F 4 .   ? 214.628 131.463 197.959 1.00 197.87 ? 1403 NAG A C5   1 
HETATM 4516 C C6   . NAG F 4 .   ? 214.030 130.412 198.904 1.00 195.18 ? 1403 NAG A C6   1 
HETATM 4517 C C7   . NAG F 4 .   ? 214.468 136.391 195.847 1.00 196.96 ? 1403 NAG A C7   1 
HETATM 4518 C C8   . NAG F 4 .   ? 215.090 137.429 194.904 1.00 193.96 ? 1403 NAG A C8   1 
HETATM 4519 N N2   . NAG F 4 .   ? 215.208 135.320 196.127 1.00 198.25 ? 1403 NAG A N2   1 
HETATM 4520 O O3   . NAG F 4 .   ? 216.700 134.604 198.511 1.00 197.92 ? 1403 NAG A O3   1 
HETATM 4521 O O4   . NAG F 4 .   ? 216.696 131.858 199.183 1.00 196.99 ? 1403 NAG A O4   1 
HETATM 4522 O O5   . NAG F 4 .   ? 213.525 132.147 197.238 1.00 198.17 ? 1403 NAG A O5   1 
HETATM 4523 O O6   . NAG F 4 .   ? 213.142 131.032 199.854 1.00 193.96 ? 1403 NAG A O6   1 
HETATM 4524 O O7   . NAG F 4 .   ? 213.339 136.525 196.313 1.00 197.40 ? 1403 NAG A O7   1 
HETATM 4525 H H1   . NAG F 4 .   ? 214.556 132.726 195.509 1.00 195.98 ? 1403 NAG A H1   1 
HETATM 4526 H H2   . NAG F 4 .   ? 214.115 134.714 197.804 1.00 196.06 ? 1403 NAG A H2   1 
HETATM 4527 H H3   . NAG F 4 .   ? 216.618 133.200 196.980 1.00 196.25 ? 1403 NAG A H3   1 
HETATM 4528 H H4   . NAG F 4 .   ? 214.950 132.933 199.519 1.00 195.98 ? 1403 NAG A H4   1 
HETATM 4529 H H5   . NAG F 4 .   ? 215.240 130.945 197.223 1.00 195.95 ? 1403 NAG A H5   1 
HETATM 4530 H H61  . NAG F 4 .   ? 213.468 129.679 198.328 1.00 195.64 ? 1403 NAG A H61  1 
HETATM 4531 H H62  . NAG F 4 .   ? 214.820 129.889 199.438 1.00 195.43 ? 1403 NAG A H62  1 
HETATM 4532 H H81  . NAG F 4 .   ? 215.884 137.895 195.353 1.00 195.00 ? 1403 NAG A H81  1 
HETATM 4533 H H82  . NAG F 4 .   ? 215.424 136.991 194.037 1.00 194.67 ? 1403 NAG A H82  1 
HETATM 4534 H H83  . NAG F 4 .   ? 214.406 138.151 194.644 1.00 195.18 ? 1403 NAG A H83  1 
HETATM 4535 H HN2  . NAG F 4 .   ? 216.075 135.189 195.632 1.00 195.76 ? 1403 NAG A HN2  1 
HETATM 4536 H HO3  . NAG F 4 .   ? 216.930 135.345 197.948 1.00 195.81 ? 1403 NAG A HO3  1 
HETATM 4537 H HO4  . NAG F 4 .   ? 217.274 132.557 199.489 1.00 195.91 ? 1403 NAG A HO4  1 
HETATM 4538 H HO6  . NAG F 4 .   ? 212.743 130.342 200.383 1.00 195.50 ? 1403 NAG A HO6  1 
HETATM 4539 C C1   . NAG G 4 .   ? 197.604 119.428 168.830 1.00 166.83 ? 1404 NAG A C1   1 
HETATM 4540 C C2   . NAG G 4 .   ? 196.791 118.363 168.080 1.00 166.78 ? 1404 NAG A C2   1 
HETATM 4541 C C3   . NAG G 4 .   ? 197.553 117.877 166.841 1.00 170.26 ? 1404 NAG A C3   1 
HETATM 4542 C C4   . NAG G 4 .   ? 197.946 119.062 165.951 1.00 171.51 ? 1404 NAG A C4   1 
HETATM 4543 C C5   . NAG G 4 .   ? 198.766 120.093 166.740 1.00 169.68 ? 1404 NAG A C5   1 
HETATM 4544 C C6   . NAG G 4 .   ? 199.128 121.340 165.929 1.00 166.38 ? 1404 NAG A C6   1 
HETATM 4545 C C7   . NAG G 4 .   ? 195.429 117.158 169.712 1.00 163.97 ? 1404 NAG A C7   1 
HETATM 4546 C C8   . NAG G 4 .   ? 195.321 115.942 170.639 1.00 162.66 ? 1404 NAG A C8   1 
HETATM 4547 N N2   . NAG G 4 .   ? 196.542 117.249 168.992 1.00 164.93 ? 1404 NAG A N2   1 
HETATM 4548 O O3   . NAG G 4 .   ? 196.733 116.955 166.067 1.00 167.38 ? 1404 NAG A O3   1 
HETATM 4549 O O4   . NAG G 4 .   ? 198.756 118.538 164.876 1.00 167.24 ? 1404 NAG A O4   1 
HETATM 4550 O O5   . NAG G 4 .   ? 198.003 120.512 167.940 1.00 166.91 ? 1404 NAG A O5   1 
HETATM 4551 O O6   . NAG G 4 .   ? 197.938 122.083 165.618 1.00 166.80 ? 1404 NAG A O6   1 
HETATM 4552 O O7   . NAG G 4 .   ? 194.542 118.005 169.638 1.00 164.33 ? 1404 NAG A O7   1 
HETATM 4553 H H1   . NAG G 4 .   ? 198.497 118.972 169.256 1.00 164.82 ? 1404 NAG A H1   1 
HETATM 4554 H H2   . NAG G 4 .   ? 195.846 118.799 167.754 1.00 164.75 ? 1404 NAG A H2   1 
HETATM 4555 H H3   . NAG G 4 .   ? 198.455 117.356 167.163 1.00 165.70 ? 1404 NAG A H3   1 
HETATM 4556 H H4   . NAG G 4 .   ? 197.051 119.527 165.536 1.00 165.56 ? 1404 NAG A H4   1 
HETATM 4557 H H5   . NAG G 4 .   ? 199.691 119.622 167.072 1.00 165.58 ? 1404 NAG A H5   1 
HETATM 4558 H H61  . NAG G 4 .   ? 199.799 121.972 166.510 1.00 164.67 ? 1404 NAG A H61  1 
HETATM 4559 H H62  . NAG G 4 .   ? 199.638 121.063 165.006 1.00 165.14 ? 1404 NAG A H62  1 
HETATM 4560 H H81  . NAG G 4 .   ? 194.391 115.987 171.205 1.00 164.91 ? 1404 NAG A H81  1 
HETATM 4561 H H82  . NAG G 4 .   ? 195.336 115.028 170.047 1.00 164.89 ? 1404 NAG A H82  1 
HETATM 4562 H H83  . NAG G 4 .   ? 196.162 115.935 171.334 1.00 164.39 ? 1404 NAG A H83  1 
HETATM 4563 H HN2  . NAG G 4 .   ? 197.279 116.577 169.149 1.00 164.73 ? 1404 NAG A HN2  1 
HETATM 4564 H HO3  . NAG G 4 .   ? 196.452 116.231 166.631 1.00 165.24 ? 1404 NAG A HO3  1 
HETATM 4565 H HO4  . NAG G 4 .   ? 198.274 117.794 164.505 1.00 164.82 ? 1404 NAG A HO4  1 
HETATM 4566 H HO6  . NAG G 4 .   ? 198.173 122.810 165.035 1.00 164.99 ? 1404 NAG A HO6  1 
HETATM 4567 C C1   . NAG H 4 .   ? 218.175 135.360 166.150 1.00 208.01 ? 1405 NAG A C1   1 
HETATM 4568 C C2   . NAG H 4 .   ? 219.509 134.616 166.352 1.00 209.35 ? 1405 NAG A C2   1 
HETATM 4569 C C3   . NAG H 4 .   ? 220.628 135.502 165.785 1.00 207.33 ? 1405 NAG A C3   1 
HETATM 4570 C C4   . NAG H 4 .   ? 220.373 135.770 164.293 1.00 206.54 ? 1405 NAG A C4   1 
HETATM 4571 C C5   . NAG H 4 .   ? 218.983 136.390 164.042 1.00 204.42 ? 1405 NAG A C5   1 
HETATM 4572 C C6   . NAG H 4 .   ? 218.624 136.498 162.552 1.00 203.18 ? 1405 NAG A C6   1 
HETATM 4573 C C7   . NAG H 4 .   ? 219.878 133.101 168.256 1.00 206.88 ? 1405 NAG A C7   1 
HETATM 4574 C C8   . NAG H 4 .   ? 220.042 132.994 169.779 1.00 205.48 ? 1405 NAG A C8   1 
HETATM 4575 N N2   . NAG H 4 .   ? 219.726 134.332 167.775 1.00 210.44 ? 1405 NAG A N2   1 
HETATM 4576 O O3   . NAG H 4 .   ? 221.929 134.867 165.938 1.00 207.37 ? 1405 NAG A O3   1 
HETATM 4577 O O4   . NAG H 4 .   ? 221.390 136.698 163.851 1.00 205.62 ? 1405 NAG A O4   1 
HETATM 4578 O O5   . NAG H 4 .   ? 217.935 135.586 164.726 1.00 203.06 ? 1405 NAG A O5   1 
HETATM 4579 O O6   . NAG H 4 .   ? 218.506 135.184 161.967 1.00 202.04 ? 1405 NAG A O6   1 
HETATM 4580 O O7   . NAG H 4 .   ? 219.895 132.112 167.526 1.00 203.42 ? 1405 NAG A O7   1 
HETATM 4581 H H1   . NAG H 4 .   ? 218.210 136.323 166.661 1.00 204.50 ? 1405 NAG A H1   1 
HETATM 4582 H H2   . NAG H 4 .   ? 219.479 133.685 165.786 1.00 204.72 ? 1405 NAG A H2   1 
HETATM 4583 H H3   . NAG H 4 .   ? 220.641 136.447 166.327 1.00 204.44 ? 1405 NAG A H3   1 
HETATM 4584 H H4   . NAG H 4 .   ? 220.473 134.839 163.737 1.00 204.55 ? 1405 NAG A H4   1 
HETATM 4585 H H5   . NAG H 4 .   ? 218.968 137.392 164.469 1.00 204.40 ? 1405 NAG A H5   1 
HETATM 4586 H H61  . NAG H 4 .   ? 217.673 137.019 162.444 1.00 204.06 ? 1405 NAG A H61  1 
HETATM 4587 H H62  . NAG H 4 .   ? 219.384 137.066 162.017 1.00 204.30 ? 1405 NAG A H62  1 
HETATM 4588 H H81  . NAG H 4 .   ? 220.112 131.947 170.073 1.00 204.10 ? 1405 NAG A H81  1 
HETATM 4589 H H82  . NAG H 4 .   ? 219.179 133.446 170.269 1.00 203.65 ? 1405 NAG A H82  1 
HETATM 4590 H H83  . NAG H 4 .   ? 220.947 133.515 170.090 1.00 204.21 ? 1405 NAG A H83  1 
HETATM 4591 H HN2  . NAG H 4 .   ? 219.653 135.098 168.430 1.00 204.62 ? 1405 NAG A HN2  1 
HETATM 4592 H HO3  . NAG H 4 .   ? 222.060 134.641 166.861 1.00 204.68 ? 1405 NAG A HO3  1 
HETATM 4593 H HO4  . NAG H 4 .   ? 222.229 136.352 164.166 1.00 204.39 ? 1405 NAG A HO4  1 
HETATM 4594 H HO6  . NAG H 4 .   ? 218.221 135.282 161.056 1.00 204.14 ? 1405 NAG A HO6  1 
HETATM 4595 C C1   . NAG I 4 .   ? 208.339 158.427 179.355 1.00 227.58 ? 1406 NAG A C1   1 
HETATM 4596 C C2   . NAG I 4 .   ? 208.927 159.858 179.256 1.00 228.11 ? 1406 NAG A C2   1 
HETATM 4597 C C3   . NAG I 4 .   ? 207.766 160.861 179.125 1.00 228.09 ? 1406 NAG A C3   1 
HETATM 4598 C C4   . NAG I 4 .   ? 206.888 160.519 177.909 1.00 228.20 ? 1406 NAG A C4   1 
HETATM 4599 C C5   . NAG I 4 .   ? 206.366 159.072 177.995 1.00 226.80 ? 1406 NAG A C5   1 
HETATM 4600 C C6   . NAG I 4 .   ? 205.552 158.614 176.778 1.00 224.65 ? 1406 NAG A C6   1 
HETATM 4601 C C7   . NAG I 4 .   ? 211.051 159.867 180.501 1.00 222.63 ? 1406 NAG A C7   1 
HETATM 4602 C C8   . NAG I 4 .   ? 211.802 160.387 181.733 1.00 219.82 ? 1406 NAG A C8   1 
HETATM 4603 N N2   . NAG I 4 .   ? 209.762 160.180 180.421 1.00 225.43 ? 1406 NAG A N2   1 
HETATM 4604 O O3   . NAG I 4 .   ? 208.260 162.221 178.981 1.00 224.71 ? 1406 NAG A O3   1 
HETATM 4605 O O4   . NAG I 4 .   ? 205.771 161.442 177.916 1.00 225.93 ? 1406 NAG A O4   1 
HETATM 4606 O O5   . NAG I 4 .   ? 207.517 158.154 178.173 1.00 227.72 ? 1406 NAG A O5   1 
HETATM 4607 O O6   . NAG I 4 .   ? 206.345 158.678 175.582 1.00 224.42 ? 1406 NAG A O6   1 
HETATM 4608 O O7   . NAG I 4 .   ? 211.599 159.181 179.639 1.00 222.17 ? 1406 NAG A O7   1 
HETATM 4609 H H1   . NAG I 4 .   ? 207.723 158.323 180.248 1.00 224.06 ? 1406 NAG A H1   1 
HETATM 4610 H H2   . NAG I 4 .   ? 209.542 159.921 178.359 1.00 224.36 ? 1406 NAG A H2   1 
HETATM 4611 H H3   . NAG I 4 .   ? 207.154 160.813 180.025 1.00 224.68 ? 1406 NAG A H3   1 
HETATM 4612 H H4   . NAG I 4 .   ? 207.462 160.662 176.995 1.00 224.68 ? 1406 NAG A H4   1 
HETATM 4613 H H5   . NAG I 4 .   ? 205.729 158.986 178.874 1.00 224.15 ? 1406 NAG A H5   1 
HETATM 4614 H H61  . NAG I 4 .   ? 205.224 157.588 176.925 1.00 224.05 ? 1406 NAG A H61  1 
HETATM 4615 H H62  . NAG I 4 .   ? 204.669 159.235 176.658 1.00 224.10 ? 1406 NAG A H62  1 
HETATM 4616 H H81  . NAG I 4 .   ? 211.362 159.964 182.633 1.00 223.57 ? 1406 NAG A H81  1 
HETATM 4617 H H82  . NAG I 4 .   ? 212.850 160.100 181.677 1.00 223.38 ? 1406 NAG A H82  1 
HETATM 4618 H H83  . NAG I 4 .   ? 211.732 161.471 181.775 1.00 223.61 ? 1406 NAG A H83  1 
HETATM 4619 H HN2  . NAG I 4 .   ? 209.340 160.720 181.160 1.00 224.10 ? 1406 NAG A HN2  1 
HETATM 4620 H HO3  . NAG I 4 .   ? 207.508 162.780 178.788 1.00 224.08 ? 1406 NAG A HO3  1 
HETATM 4621 H HO4  . NAG I 4 .   ? 205.342 161.425 177.062 1.00 224.24 ? 1406 NAG A HO4  1 
HETATM 4622 H HO6  . NAG I 4 .   ? 205.859 158.252 174.873 1.00 224.11 ? 1406 NAG A HO6  1 
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