data_9MZU
# 
_entry.id   9MZU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MZU         pdb_00009mzu 10.2210/pdb9mzu/pdb 
WWPDB D_1000290361 ?            ?                   
EMDB  EMD-48769    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-04-16 ? 
2  'EM metadata'     1 0 2025-04-16 ? 
3  'Additional map'  1 0 2025-04-16 1 
4  FSC               1 0 2025-04-16 ? 
5  'Half map'        1 0 2025-04-16 1 
6  'Half map'        1 0 2025-04-16 2 
7  Image             1 0 2025-04-16 ? 
8  Mask              1 0 2025-04-16 1 
9  Mask              1 0 2025-04-16 2 
10 'Primary map'     1 0 2025-04-16 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Additional map'  repository 'Initial release' ? ? 
4  4  FSC               repository 'Initial release' ? ? 
5  5  'Half map'        repository 'Initial release' ? ? 
6  6  'Half map'        repository 'Initial release' ? ? 
7  7  Image             repository 'Initial release' ? ? 
8  8  Mask              repository 'Initial release' ? ? 
9  9  Mask              repository 'Initial release' ? ? 
10 10 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MZU 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of PorKN from Porphyromonas gingivalis' 
_pdbx_database_related.db_id          EMD-48769 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              susan.lea@nih.gov 
_pdbx_contact_author.name_first         Susan 
_pdbx_contact_author.name_last          Lea 
_pdbx_contact_author.name_mi            M 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9287-8053 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lea, S.M.'   1 ? 
'Deme, J.C.'  2 ? 
'Berks, B.C.' 3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'A  central role for disulfide bonds in Bacteroidota protein transportation and gliding motility' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, X.'       1 ? 
primary 'Avaramova, M.' 2 ? 
primary 'Deme, J.C.'    3 ? 
primary 'Lundgren, C.'  4 ? 
primary 'Jones, R.M.'   5 ? 
primary 'Lea, S.M.'     6 ? 
primary 'Berks, B.C.'   7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     nat PorK 55967.539 3 ? ? ? ? 
2 polymer     nat 'Gliding motility protein GldN' 41729.207 3 ? ? ? ? 
3 branched    man 
;alpha-L-fucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose
;
810.702   6 ? ? ? ? 
4 non-polymer syn 'CALCIUM ION' 40.078    3 ? ? ? ? 
5 non-polymer syn alpha-D-mannopyranose 180.156   6 ? ? ? ? 
6 water       nat water 18.015    3 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MCRKNRFFALAGFFLFGVFTISSCGSSKRAVGGELTGAKLSSWNEPSPFGMIQVPRGSIVLGNKEADSLWGIPAESRPIS
VDAFWMDRTEITNAQYRQFVYYVRDSIIRERLADPAYGGNEEYKITENKFGEPVTPHLDWSKPIPSEKRATEEEIAAINS
VYYTNPVTHDRKLNPDQMVYRYEVYDYRSAALREHQLKAAKRNLNTDIKVDPNAVVMISKDTAFVDESGNIISETITRPL
SSEYDFLNTYIVPIYPDETCWVNDFPNARTEIYTRMYFNHPGYDDYPVVGISWEQAQAFCAWRSEFFRKGIRLPEGQIMD
DFRLPTEAEWEYAARMGDSNNKYPWSTEDLRTGRGCFLGNFKPGEGDYTADGHLIPSRVSSFSPNDFGLYDMAGNVAEWT
STAFSESGLKQMSDINPELEYKAALTDPYILKQKVVRGGSWKDVARFIRSATRSHEYQNVGRSYIGFRCVRTSIAFSSGK
APKSSRRSTKK
;
;MCRKNRFFALAGFFLFGVFTISSCGSSKRAVGGELTGAKLSSWNEPSPFGMIQVPRGSIVLGNKEADSLWGIPAESRPIS
VDAFWMDRTEITNAQYRQFVYYVRDSIIRERLADPAYGGNEEYKITENKFGEPVTPHLDWSKPIPSEKRATEEEIAAINS
VYYTNPVTHDRKLNPDQMVYRYEVYDYRSAALREHQLKAAKRNLNTDIKVDPNAVVMISKDTAFVDESGNIISETITRPL
SSEYDFLNTYIVPIYPDETCWVNDFPNARTEIYTRMYFNHPGYDDYPVVGISWEQAQAFCAWRSEFFRKGIRLPEGQIMD
DFRLPTEAEWEYAARMGDSNNKYPWSTEDLRTGRGCFLGNFKPGEGDYTADGHLIPSRVSSFSPNDFGLYDMAGNVAEWT
STAFSESGLKQMSDINPELEYKAALTDPYILKQKVVRGGSWKDVARFIRSATRSHEYQNVGRSYIGFRCVRTSIAFSSGK
APKSSRRSTKK
;
A,C,E ? 
2 'polypeptide(L)' no no 
;MFMKVFKAVIGAILAATVSISSVAQENTNNRSPQVGRAPRNTEVEQTTTLSNRAQEFNRRLTQKTDNAPWRRVVYRRVDL
MEESNAVLYYPPRPIGDRKNLFSTIFGLINSNSLDVYEYLDGFEAFTDQYKIKFQEFLDRFGIYYQPSTNKNAELFKVAD
SDIPSAEVKAYYVKEEWYFTPTNSDVDIKIQAICPIMTGQDEFGEVRNQPLFWIPYENIRPYIARERVMLSSLNNTRNST
IDDFFRLNLYKGDIVKTENLHNRALAEYCPTPDSMKMESKRIDKELQGFRDGLFVTQDTTWMKQAETKKSKGKKLEKARG
KNITSRTRGQGEGAAETEAVEPKKQKASKNKAATRSVRRRK
;
;MFMKVFKAVIGAILAATVSISSVAQENTNNRSPQVGRAPRNTEVEQTTTLSNRAQEFNRRLTQKTDNAPWRRVVYRRVDL
MEESNAVLYYPPRPIGDRKNLFSTIFGLINSNSLDVYEYLDGFEAFTDQYKIKFQEFLDRFGIYYQPSTNKNAELFKVAD
SDIPSAEVKAYYVKEEWYFTPTNSDVDIKIQAICPIMTGQDEFGEVRNQPLFWIPYENIRPYIARERVMLSSLNNTRNST
IDDFFRLNLYKGDIVKTENLHNRALAEYCPTPDSMKMESKRIDKELQGFRDGLFVTQDTTWMKQAETKKSKGKKLEKARG
KNITSRTRGQGEGAAETEAVEPKKQKASKNKAATRSVRRRK
;
B,D,F ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'CALCIUM ION'         CA  
5 alpha-D-mannopyranose MAN 
6 water                 HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   CYS n 
1 3   ARG n 
1 4   LYS n 
1 5   ASN n 
1 6   ARG n 
1 7   PHE n 
1 8   PHE n 
1 9   ALA n 
1 10  LEU n 
1 11  ALA n 
1 12  GLY n 
1 13  PHE n 
1 14  PHE n 
1 15  LEU n 
1 16  PHE n 
1 17  GLY n 
1 18  VAL n 
1 19  PHE n 
1 20  THR n 
1 21  ILE n 
1 22  SER n 
1 23  SER n 
1 24  CYS n 
1 25  GLY n 
1 26  SER n 
1 27  SER n 
1 28  LYS n 
1 29  ARG n 
1 30  ALA n 
1 31  VAL n 
1 32  GLY n 
1 33  GLY n 
1 34  GLU n 
1 35  LEU n 
1 36  THR n 
1 37  GLY n 
1 38  ALA n 
1 39  LYS n 
1 40  LEU n 
1 41  SER n 
1 42  SER n 
1 43  TRP n 
1 44  ASN n 
1 45  GLU n 
1 46  PRO n 
1 47  SER n 
1 48  PRO n 
1 49  PHE n 
1 50  GLY n 
1 51  MET n 
1 52  ILE n 
1 53  GLN n 
1 54  VAL n 
1 55  PRO n 
1 56  ARG n 
1 57  GLY n 
1 58  SER n 
1 59  ILE n 
1 60  VAL n 
1 61  LEU n 
1 62  GLY n 
1 63  ASN n 
1 64  LYS n 
1 65  GLU n 
1 66  ALA n 
1 67  ASP n 
1 68  SER n 
1 69  LEU n 
1 70  TRP n 
1 71  GLY n 
1 72  ILE n 
1 73  PRO n 
1 74  ALA n 
1 75  GLU n 
1 76  SER n 
1 77  ARG n 
1 78  PRO n 
1 79  ILE n 
1 80  SER n 
1 81  VAL n 
1 82  ASP n 
1 83  ALA n 
1 84  PHE n 
1 85  TRP n 
1 86  MET n 
1 87  ASP n 
1 88  ARG n 
1 89  THR n 
1 90  GLU n 
1 91  ILE n 
1 92  THR n 
1 93  ASN n 
1 94  ALA n 
1 95  GLN n 
1 96  TYR n 
1 97  ARG n 
1 98  GLN n 
1 99  PHE n 
1 100 VAL n 
1 101 TYR n 
1 102 TYR n 
1 103 VAL n 
1 104 ARG n 
1 105 ASP n 
1 106 SER n 
1 107 ILE n 
1 108 ILE n 
1 109 ARG n 
1 110 GLU n 
1 111 ARG n 
1 112 LEU n 
1 113 ALA n 
1 114 ASP n 
1 115 PRO n 
1 116 ALA n 
1 117 TYR n 
1 118 GLY n 
1 119 GLY n 
1 120 ASN n 
1 121 GLU n 
1 122 GLU n 
1 123 TYR n 
1 124 LYS n 
1 125 ILE n 
1 126 THR n 
1 127 GLU n 
1 128 ASN n 
1 129 LYS n 
1 130 PHE n 
1 131 GLY n 
1 132 GLU n 
1 133 PRO n 
1 134 VAL n 
1 135 THR n 
1 136 PRO n 
1 137 HIS n 
1 138 LEU n 
1 139 ASP n 
1 140 TRP n 
1 141 SER n 
1 142 LYS n 
1 143 PRO n 
1 144 ILE n 
1 145 PRO n 
1 146 SER n 
1 147 GLU n 
1 148 LYS n 
1 149 ARG n 
1 150 ALA n 
1 151 THR n 
1 152 GLU n 
1 153 GLU n 
1 154 GLU n 
1 155 ILE n 
1 156 ALA n 
1 157 ALA n 
1 158 ILE n 
1 159 ASN n 
1 160 SER n 
1 161 VAL n 
1 162 TYR n 
1 163 TYR n 
1 164 THR n 
1 165 ASN n 
1 166 PRO n 
1 167 VAL n 
1 168 THR n 
1 169 HIS n 
1 170 ASP n 
1 171 ARG n 
1 172 LYS n 
1 173 LEU n 
1 174 ASN n 
1 175 PRO n 
1 176 ASP n 
1 177 GLN n 
1 178 MET n 
1 179 VAL n 
1 180 TYR n 
1 181 ARG n 
1 182 TYR n 
1 183 GLU n 
1 184 VAL n 
1 185 TYR n 
1 186 ASP n 
1 187 TYR n 
1 188 ARG n 
1 189 SER n 
1 190 ALA n 
1 191 ALA n 
1 192 LEU n 
1 193 ARG n 
1 194 GLU n 
1 195 HIS n 
1 196 GLN n 
1 197 LEU n 
1 198 LYS n 
1 199 ALA n 
1 200 ALA n 
1 201 LYS n 
1 202 ARG n 
1 203 ASN n 
1 204 LEU n 
1 205 ASN n 
1 206 THR n 
1 207 ASP n 
1 208 ILE n 
1 209 LYS n 
1 210 VAL n 
1 211 ASP n 
1 212 PRO n 
1 213 ASN n 
1 214 ALA n 
1 215 VAL n 
1 216 VAL n 
1 217 MET n 
1 218 ILE n 
1 219 SER n 
1 220 LYS n 
1 221 ASP n 
1 222 THR n 
1 223 ALA n 
1 224 PHE n 
1 225 VAL n 
1 226 ASP n 
1 227 GLU n 
1 228 SER n 
1 229 GLY n 
1 230 ASN n 
1 231 ILE n 
1 232 ILE n 
1 233 SER n 
1 234 GLU n 
1 235 THR n 
1 236 ILE n 
1 237 THR n 
1 238 ARG n 
1 239 PRO n 
1 240 LEU n 
1 241 SER n 
1 242 SER n 
1 243 GLU n 
1 244 TYR n 
1 245 ASP n 
1 246 PHE n 
1 247 LEU n 
1 248 ASN n 
1 249 THR n 
1 250 TYR n 
1 251 ILE n 
1 252 VAL n 
1 253 PRO n 
1 254 ILE n 
1 255 TYR n 
1 256 PRO n 
1 257 ASP n 
1 258 GLU n 
1 259 THR n 
1 260 CYS n 
1 261 TRP n 
1 262 VAL n 
1 263 ASN n 
1 264 ASP n 
1 265 PHE n 
1 266 PRO n 
1 267 ASN n 
1 268 ALA n 
1 269 ARG n 
1 270 THR n 
1 271 GLU n 
1 272 ILE n 
1 273 TYR n 
1 274 THR n 
1 275 ARG n 
1 276 MET n 
1 277 TYR n 
1 278 PHE n 
1 279 ASN n 
1 280 HIS n 
1 281 PRO n 
1 282 GLY n 
1 283 TYR n 
1 284 ASP n 
1 285 ASP n 
1 286 TYR n 
1 287 PRO n 
1 288 VAL n 
1 289 VAL n 
1 290 GLY n 
1 291 ILE n 
1 292 SER n 
1 293 TRP n 
1 294 GLU n 
1 295 GLN n 
1 296 ALA n 
1 297 GLN n 
1 298 ALA n 
1 299 PHE n 
1 300 CYS n 
1 301 ALA n 
1 302 TRP n 
1 303 ARG n 
1 304 SER n 
1 305 GLU n 
1 306 PHE n 
1 307 PHE n 
1 308 ARG n 
1 309 LYS n 
1 310 GLY n 
1 311 ILE n 
1 312 ARG n 
1 313 LEU n 
1 314 PRO n 
1 315 GLU n 
1 316 GLY n 
1 317 GLN n 
1 318 ILE n 
1 319 MET n 
1 320 ASP n 
1 321 ASP n 
1 322 PHE n 
1 323 ARG n 
1 324 LEU n 
1 325 PRO n 
1 326 THR n 
1 327 GLU n 
1 328 ALA n 
1 329 GLU n 
1 330 TRP n 
1 331 GLU n 
1 332 TYR n 
1 333 ALA n 
1 334 ALA n 
1 335 ARG n 
1 336 MET n 
1 337 GLY n 
1 338 ASP n 
1 339 SER n 
1 340 ASN n 
1 341 ASN n 
1 342 LYS n 
1 343 TYR n 
1 344 PRO n 
1 345 TRP n 
1 346 SER n 
1 347 THR n 
1 348 GLU n 
1 349 ASP n 
1 350 LEU n 
1 351 ARG n 
1 352 THR n 
1 353 GLY n 
1 354 ARG n 
1 355 GLY n 
1 356 CYS n 
1 357 PHE n 
1 358 LEU n 
1 359 GLY n 
1 360 ASN n 
1 361 PHE n 
1 362 LYS n 
1 363 PRO n 
1 364 GLY n 
1 365 GLU n 
1 366 GLY n 
1 367 ASP n 
1 368 TYR n 
1 369 THR n 
1 370 ALA n 
1 371 ASP n 
1 372 GLY n 
1 373 HIS n 
1 374 LEU n 
1 375 ILE n 
1 376 PRO n 
1 377 SER n 
1 378 ARG n 
1 379 VAL n 
1 380 SER n 
1 381 SER n 
1 382 PHE n 
1 383 SER n 
1 384 PRO n 
1 385 ASN n 
1 386 ASP n 
1 387 PHE n 
1 388 GLY n 
1 389 LEU n 
1 390 TYR n 
1 391 ASP n 
1 392 MET n 
1 393 ALA n 
1 394 GLY n 
1 395 ASN n 
1 396 VAL n 
1 397 ALA n 
1 398 GLU n 
1 399 TRP n 
1 400 THR n 
1 401 SER n 
1 402 THR n 
1 403 ALA n 
1 404 PHE n 
1 405 SER n 
1 406 GLU n 
1 407 SER n 
1 408 GLY n 
1 409 LEU n 
1 410 LYS n 
1 411 GLN n 
1 412 MET n 
1 413 SER n 
1 414 ASP n 
1 415 ILE n 
1 416 ASN n 
1 417 PRO n 
1 418 GLU n 
1 419 LEU n 
1 420 GLU n 
1 421 TYR n 
1 422 LYS n 
1 423 ALA n 
1 424 ALA n 
1 425 LEU n 
1 426 THR n 
1 427 ASP n 
1 428 PRO n 
1 429 TYR n 
1 430 ILE n 
1 431 LEU n 
1 432 LYS n 
1 433 GLN n 
1 434 LYS n 
1 435 VAL n 
1 436 VAL n 
1 437 ARG n 
1 438 GLY n 
1 439 GLY n 
1 440 SER n 
1 441 TRP n 
1 442 LYS n 
1 443 ASP n 
1 444 VAL n 
1 445 ALA n 
1 446 ARG n 
1 447 PHE n 
1 448 ILE n 
1 449 ARG n 
1 450 SER n 
1 451 ALA n 
1 452 THR n 
1 453 ARG n 
1 454 SER n 
1 455 HIS n 
1 456 GLU n 
1 457 TYR n 
1 458 GLN n 
1 459 ASN n 
1 460 VAL n 
1 461 GLY n 
1 462 ARG n 
1 463 SER n 
1 464 TYR n 
1 465 ILE n 
1 466 GLY n 
1 467 PHE n 
1 468 ARG n 
1 469 CYS n 
1 470 VAL n 
1 471 ARG n 
1 472 THR n 
1 473 SER n 
1 474 ILE n 
1 475 ALA n 
1 476 PHE n 
1 477 SER n 
1 478 SER n 
1 479 GLY n 
1 480 LYS n 
1 481 ALA n 
1 482 PRO n 
1 483 LYS n 
1 484 SER n 
1 485 SER n 
1 486 ARG n 
1 487 ARG n 
1 488 SER n 
1 489 THR n 
1 490 LYS n 
1 491 LYS n 
2 1   MET n 
2 2   PHE n 
2 3   MET n 
2 4   LYS n 
2 5   VAL n 
2 6   PHE n 
2 7   LYS n 
2 8   ALA n 
2 9   VAL n 
2 10  ILE n 
2 11  GLY n 
2 12  ALA n 
2 13  ILE n 
2 14  LEU n 
2 15  ALA n 
2 16  ALA n 
2 17  THR n 
2 18  VAL n 
2 19  SER n 
2 20  ILE n 
2 21  SER n 
2 22  SER n 
2 23  VAL n 
2 24  ALA n 
2 25  GLN n 
2 26  GLU n 
2 27  ASN n 
2 28  THR n 
2 29  ASN n 
2 30  ASN n 
2 31  ARG n 
2 32  SER n 
2 33  PRO n 
2 34  GLN n 
2 35  VAL n 
2 36  GLY n 
2 37  ARG n 
2 38  ALA n 
2 39  PRO n 
2 40  ARG n 
2 41  ASN n 
2 42  THR n 
2 43  GLU n 
2 44  VAL n 
2 45  GLU n 
2 46  GLN n 
2 47  THR n 
2 48  THR n 
2 49  THR n 
2 50  LEU n 
2 51  SER n 
2 52  ASN n 
2 53  ARG n 
2 54  ALA n 
2 55  GLN n 
2 56  GLU n 
2 57  PHE n 
2 58  ASN n 
2 59  ARG n 
2 60  ARG n 
2 61  LEU n 
2 62  THR n 
2 63  GLN n 
2 64  LYS n 
2 65  THR n 
2 66  ASP n 
2 67  ASN n 
2 68  ALA n 
2 69  PRO n 
2 70  TRP n 
2 71  ARG n 
2 72  ARG n 
2 73  VAL n 
2 74  VAL n 
2 75  TYR n 
2 76  ARG n 
2 77  ARG n 
2 78  VAL n 
2 79  ASP n 
2 80  LEU n 
2 81  MET n 
2 82  GLU n 
2 83  GLU n 
2 84  SER n 
2 85  ASN n 
2 86  ALA n 
2 87  VAL n 
2 88  LEU n 
2 89  TYR n 
2 90  TYR n 
2 91  PRO n 
2 92  PRO n 
2 93  ARG n 
2 94  PRO n 
2 95  ILE n 
2 96  GLY n 
2 97  ASP n 
2 98  ARG n 
2 99  LYS n 
2 100 ASN n 
2 101 LEU n 
2 102 PHE n 
2 103 SER n 
2 104 THR n 
2 105 ILE n 
2 106 PHE n 
2 107 GLY n 
2 108 LEU n 
2 109 ILE n 
2 110 ASN n 
2 111 SER n 
2 112 ASN n 
2 113 SER n 
2 114 LEU n 
2 115 ASP n 
2 116 VAL n 
2 117 TYR n 
2 118 GLU n 
2 119 TYR n 
2 120 LEU n 
2 121 ASP n 
2 122 GLY n 
2 123 PHE n 
2 124 GLU n 
2 125 ALA n 
2 126 PHE n 
2 127 THR n 
2 128 ASP n 
2 129 GLN n 
2 130 TYR n 
2 131 LYS n 
2 132 ILE n 
2 133 LYS n 
2 134 PHE n 
2 135 GLN n 
2 136 GLU n 
2 137 PHE n 
2 138 LEU n 
2 139 ASP n 
2 140 ARG n 
2 141 PHE n 
2 142 GLY n 
2 143 ILE n 
2 144 TYR n 
2 145 TYR n 
2 146 GLN n 
2 147 PRO n 
2 148 SER n 
2 149 THR n 
2 150 ASN n 
2 151 LYS n 
2 152 ASN n 
2 153 ALA n 
2 154 GLU n 
2 155 LEU n 
2 156 PHE n 
2 157 LYS n 
2 158 VAL n 
2 159 ALA n 
2 160 ASP n 
2 161 SER n 
2 162 ASP n 
2 163 ILE n 
2 164 PRO n 
2 165 SER n 
2 166 ALA n 
2 167 GLU n 
2 168 VAL n 
2 169 LYS n 
2 170 ALA n 
2 171 TYR n 
2 172 TYR n 
2 173 VAL n 
2 174 LYS n 
2 175 GLU n 
2 176 GLU n 
2 177 TRP n 
2 178 TYR n 
2 179 PHE n 
2 180 THR n 
2 181 PRO n 
2 182 THR n 
2 183 ASN n 
2 184 SER n 
2 185 ASP n 
2 186 VAL n 
2 187 ASP n 
2 188 ILE n 
2 189 LYS n 
2 190 ILE n 
2 191 GLN n 
2 192 ALA n 
2 193 ILE n 
2 194 CYS n 
2 195 PRO n 
2 196 ILE n 
2 197 MET n 
2 198 THR n 
2 199 GLY n 
2 200 GLN n 
2 201 ASP n 
2 202 GLU n 
2 203 PHE n 
2 204 GLY n 
2 205 GLU n 
2 206 VAL n 
2 207 ARG n 
2 208 ASN n 
2 209 GLN n 
2 210 PRO n 
2 211 LEU n 
2 212 PHE n 
2 213 TRP n 
2 214 ILE n 
2 215 PRO n 
2 216 TYR n 
2 217 GLU n 
2 218 ASN n 
2 219 ILE n 
2 220 ARG n 
2 221 PRO n 
2 222 TYR n 
2 223 ILE n 
2 224 ALA n 
2 225 ARG n 
2 226 GLU n 
2 227 ARG n 
2 228 VAL n 
2 229 MET n 
2 230 LEU n 
2 231 SER n 
2 232 SER n 
2 233 LEU n 
2 234 ASN n 
2 235 ASN n 
2 236 THR n 
2 237 ARG n 
2 238 ASN n 
2 239 SER n 
2 240 THR n 
2 241 ILE n 
2 242 ASP n 
2 243 ASP n 
2 244 PHE n 
2 245 PHE n 
2 246 ARG n 
2 247 LEU n 
2 248 ASN n 
2 249 LEU n 
2 250 TYR n 
2 251 LYS n 
2 252 GLY n 
2 253 ASP n 
2 254 ILE n 
2 255 VAL n 
2 256 LYS n 
2 257 THR n 
2 258 GLU n 
2 259 ASN n 
2 260 LEU n 
2 261 HIS n 
2 262 ASN n 
2 263 ARG n 
2 264 ALA n 
2 265 LEU n 
2 266 ALA n 
2 267 GLU n 
2 268 TYR n 
2 269 CYS n 
2 270 PRO n 
2 271 THR n 
2 272 PRO n 
2 273 ASP n 
2 274 SER n 
2 275 MET n 
2 276 LYS n 
2 277 MET n 
2 278 GLU n 
2 279 SER n 
2 280 LYS n 
2 281 ARG n 
2 282 ILE n 
2 283 ASP n 
2 284 LYS n 
2 285 GLU n 
2 286 LEU n 
2 287 GLN n 
2 288 GLY n 
2 289 PHE n 
2 290 ARG n 
2 291 ASP n 
2 292 GLY n 
2 293 LEU n 
2 294 PHE n 
2 295 VAL n 
2 296 THR n 
2 297 GLN n 
2 298 ASP n 
2 299 THR n 
2 300 THR n 
2 301 TRP n 
2 302 MET n 
2 303 LYS n 
2 304 GLN n 
2 305 ALA n 
2 306 GLU n 
2 307 THR n 
2 308 LYS n 
2 309 LYS n 
2 310 SER n 
2 311 LYS n 
2 312 GLY n 
2 313 LYS n 
2 314 LYS n 
2 315 LEU n 
2 316 GLU n 
2 317 LYS n 
2 318 ALA n 
2 319 ARG n 
2 320 GLY n 
2 321 LYS n 
2 322 ASN n 
2 323 ILE n 
2 324 THR n 
2 325 SER n 
2 326 ARG n 
2 327 THR n 
2 328 ARG n 
2 329 GLY n 
2 330 GLN n 
2 331 GLY n 
2 332 GLU n 
2 333 GLY n 
2 334 ALA n 
2 335 ALA n 
2 336 GLU n 
2 337 THR n 
2 338 GLU n 
2 339 ALA n 
2 340 VAL n 
2 341 GLU n 
2 342 PRO n 
2 343 LYS n 
2 344 LYS n 
2 345 GLN n 
2 346 LYS n 
2 347 ALA n 
2 348 SER n 
2 349 LYS n 
2 350 ASN n 
2 351 LYS n 
2 352 ALA n 
2 353 ALA n 
2 354 THR n 
2 355 ARG n 
2 356 SER n 
2 357 VAL n 
2 358 ARG n 
2 359 ARG n 
2 360 ARG n 
2 361 LYS n 
# 
loop_
_entity_src_nat.entity_id 
_entity_src_nat.pdbx_src_id 
_entity_src_nat.pdbx_alt_source_flag 
_entity_src_nat.pdbx_beg_seq_num 
_entity_src_nat.pdbx_end_seq_num 
_entity_src_nat.common_name 
_entity_src_nat.pdbx_organism_scientific 
_entity_src_nat.pdbx_ncbi_taxonomy_id 
_entity_src_nat.genus 
_entity_src_nat.species 
_entity_src_nat.strain 
_entity_src_nat.tissue 
_entity_src_nat.tissue_fraction 
_entity_src_nat.pdbx_secretion 
_entity_src_nat.pdbx_fragment 
_entity_src_nat.pdbx_variant 
_entity_src_nat.pdbx_cell_line 
_entity_src_nat.pdbx_atcc 
_entity_src_nat.pdbx_cellular_location 
_entity_src_nat.pdbx_organ 
_entity_src_nat.pdbx_organelle 
_entity_src_nat.pdbx_cell 
_entity_src_nat.pdbx_plasmid_name 
_entity_src_nat.pdbx_plasmid_details 
_entity_src_nat.details 
1 1 sample 1 491 ? 'Porphyromonas gingivalis' 837 ? ? '(strain ATCC BAA-308 / W83)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 1 361 ? 'Porphyromonas gingivalis' 837 ? ? '(strain ATCC BAA-308 / W83)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   3 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 'LFucpa1-4DGlcpa1-4DGlcpAa1-2[LRhapa1-4]DManpa1-ROH' 'Glycam Condensed Sequence' GMML       1.0   
2 3 
'WURCS=2.0/5,5,4/[a1122h-1a_1-5][a2122A-1a_1-5][a2122h-1a_1-5][a1221m-1a_1-5][a2211m-1a_1-5]/1-2-3-4-5/a2-b1_a4-e1_b4-c1_c4-d1' 
WURCS                       PDB2Glycan 1.1.0 
3 3 '[][D-1-deoxy-Manp]{[(2+1)][a-D-GlcpA]{[(4+1)][a-D-Glcp]{[(4+1)][a-L-Fucp]{}}}[(4+1)][a-L-Rhap]{}}' LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 3 2 GCU C1 O1 1 MAN O2 HO2 sing ? 
2 3 3 GLC C1 O1 2 GCU O4 HO4 sing ? 
3 3 4 FUC C1 O1 3 GLC O4 HO4 sing ? 
4 3 5 RAM C1 O1 1 MAN O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                 ? 'C4 H7 N O4'     133.103 
CA  non-polymer                   . 'CALCIUM ION'                   ? 'Ca 2'           40.078  
CYS 'L-peptide linking'           y CYSTEINE                        ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose            
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose'     'C6 H12 O5'      164.156 
GCU 'D-saccharide, alpha linking' . 'alpha-D-glucopyranuronic acid' 'alpha-D-glucuronic acid; D-glucuronic acid; glucuronic acid' 
'C6 H10 O7'      194.139 
GLC 'D-saccharide, alpha linking' . alpha-D-glucopyranose           'alpha-D-glucose; D-glucose; glucose' 'C6 H12 O6'      180.156 
GLN 'L-peptide linking'           y GLUTAMINE                       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                 ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer                   . WATER                           ? 'H2 O'           18.015  
ILE 'L-peptide linking'           y ISOLEUCINE                      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                          ? 'C6 H15 N2 O2 1' 147.195 
MAN 'D-saccharide, alpha linking' . alpha-D-mannopyranose           'alpha-D-mannose; D-mannose; mannose' 'C6 H12 O6'      180.156 
MET 'L-peptide linking'           y METHIONINE                      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'           y PHENYLALANINE                   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                         ? 'C5 H9 N O2'     115.130 
RAM 'L-saccharide, alpha linking' . alpha-L-rhamnopyranose          
'alpha-L-rhamnose; 6-deoxy-alpha-L-mannopyranose; L-rhamnose; rhamnose' 'C6 H12 O5'      164.156 
SER 'L-peptide linking'           y SERINE                          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa                      
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose            
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp                    
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc                         
GCU 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpAa                     
GCU 'COMMON NAME'                         GMML     1.0 'a-D-glucopyranuronic acid' 
GCU 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-GlcpA                   
GCU 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcA                        
GLC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpa                      
GLC 'COMMON NAME'                         GMML     1.0 a-D-glucopyranose           
GLC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Glcp                    
GLC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Glc                         
MAN 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpa                      
MAN 'COMMON NAME'                         GMML     1.0 a-D-mannopyranose           
MAN 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-D-Manp                    
MAN 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                         
RAM 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LRhapa                      
RAM 'COMMON NAME'                         GMML     1.0 a-L-rhamnopyranose          
RAM 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Rhap                    
RAM 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Rha                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   CYS 2   2   ?   ?   ?   A . n 
A 1 3   ARG 3   3   ?   ?   ?   A . n 
A 1 4   LYS 4   4   ?   ?   ?   A . n 
A 1 5   ASN 5   5   ?   ?   ?   A . n 
A 1 6   ARG 6   6   ?   ?   ?   A . n 
A 1 7   PHE 7   7   ?   ?   ?   A . n 
A 1 8   PHE 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  LEU 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  GLY 12  12  ?   ?   ?   A . n 
A 1 13  PHE 13  13  ?   ?   ?   A . n 
A 1 14  PHE 14  14  ?   ?   ?   A . n 
A 1 15  LEU 15  15  ?   ?   ?   A . n 
A 1 16  PHE 16  16  ?   ?   ?   A . n 
A 1 17  GLY 17  17  ?   ?   ?   A . n 
A 1 18  VAL 18  18  ?   ?   ?   A . n 
A 1 19  PHE 19  19  ?   ?   ?   A . n 
A 1 20  THR 20  20  ?   ?   ?   A . n 
A 1 21  ILE 21  21  ?   ?   ?   A . n 
A 1 22  SER 22  22  ?   ?   ?   A . n 
A 1 23  SER 23  23  ?   ?   ?   A . n 
A 1 24  CYS 24  24  ?   ?   ?   A . n 
A 1 25  GLY 25  25  ?   ?   ?   A . n 
A 1 26  SER 26  26  ?   ?   ?   A . n 
A 1 27  SER 27  27  ?   ?   ?   A . n 
A 1 28  LYS 28  28  ?   ?   ?   A . n 
A 1 29  ARG 29  29  ?   ?   ?   A . n 
A 1 30  ALA 30  30  ?   ?   ?   A . n 
A 1 31  VAL 31  31  ?   ?   ?   A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  GLU 34  34  34  GLU GLU A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  THR 36  36  36  THR THR A . n 
A 1 37  GLY 37  37  37  GLY GLY A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  LYS 39  39  39  LYS LYS A . n 
A 1 40  LEU 40  40  40  LEU LEU A . n 
A 1 41  SER 41  41  41  SER SER A . n 
A 1 42  SER 42  42  42  SER SER A . n 
A 1 43  TRP 43  43  43  TRP TRP A . n 
A 1 44  ASN 44  44  44  ASN ASN A . n 
A 1 45  GLU 45  45  45  GLU GLU A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  PRO 48  48  48  PRO PRO A . n 
A 1 49  PHE 49  49  49  PHE PHE A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  MET 51  51  51  MET MET A . n 
A 1 52  ILE 52  52  52  ILE ILE A . n 
A 1 53  GLN 53  53  53  GLN GLN A . n 
A 1 54  VAL 54  54  54  VAL VAL A . n 
A 1 55  PRO 55  55  55  PRO PRO A . n 
A 1 56  ARG 56  56  56  ARG ARG A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  SER 58  58  58  SER SER A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  LYS 64  64  64  LYS LYS A . n 
A 1 65  GLU 65  65  65  GLU GLU A . n 
A 1 66  ALA 66  66  66  ALA ALA A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  SER 68  68  68  SER SER A . n 
A 1 69  LEU 69  69  69  LEU LEU A . n 
A 1 70  TRP 70  70  70  TRP TRP A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ILE 72  72  72  ILE ILE A . n 
A 1 73  PRO 73  73  73  PRO PRO A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  GLU 75  75  75  GLU GLU A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  ARG 77  77  77  ARG ARG A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  ILE 79  79  79  ILE ILE A . n 
A 1 80  SER 80  80  80  SER SER A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  ASP 82  82  82  ASP ASP A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  PHE 84  84  84  PHE PHE A . n 
A 1 85  TRP 85  85  85  TRP TRP A . n 
A 1 86  MET 86  86  86  MET MET A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  ILE 91  91  91  ILE ILE A . n 
A 1 92  THR 92  92  92  THR THR A . n 
A 1 93  ASN 93  93  93  ASN ASN A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  GLN 95  95  95  GLN GLN A . n 
A 1 96  TYR 96  96  96  TYR TYR A . n 
A 1 97  ARG 97  97  97  ARG ARG A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 VAL 100 100 100 VAL VAL A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 TYR 102 102 102 TYR TYR A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 ARG 104 104 104 ARG ARG A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ILE 108 108 108 ILE ILE A . n 
A 1 109 ARG 109 109 109 ARG ARG A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 TYR 117 117 117 TYR TYR A . n 
A 1 118 GLY 118 118 118 GLY GLY A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 GLU 122 122 122 GLU GLU A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 THR 126 126 126 THR THR A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 ASN 128 128 128 ASN ASN A . n 
A 1 129 LYS 129 129 129 LYS LYS A . n 
A 1 130 PHE 130 130 130 PHE PHE A . n 
A 1 131 GLY 131 131 131 GLY GLY A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 ASP 139 139 139 ASP ASP A . n 
A 1 140 TRP 140 140 140 TRP TRP A . n 
A 1 141 SER 141 141 141 SER SER A . n 
A 1 142 LYS 142 142 142 LYS LYS A . n 
A 1 143 PRO 143 143 143 PRO PRO A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 SER 146 146 146 SER SER A . n 
A 1 147 GLU 147 147 147 GLU GLU A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 THR 151 151 151 THR THR A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 GLU 154 154 154 GLU GLU A . n 
A 1 155 ILE 155 155 155 ILE ILE A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 ASN 159 159 159 ASN ASN A . n 
A 1 160 SER 160 160 160 SER SER A . n 
A 1 161 VAL 161 161 161 VAL VAL A . n 
A 1 162 TYR 162 162 162 TYR TYR A . n 
A 1 163 TYR 163 163 163 TYR TYR A . n 
A 1 164 THR 164 164 164 THR THR A . n 
A 1 165 ASN 165 165 165 ASN ASN A . n 
A 1 166 PRO 166 166 166 PRO PRO A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 THR 168 168 168 THR THR A . n 
A 1 169 HIS 169 169 169 HIS HIS A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 LYS 172 172 172 LYS LYS A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 ASN 174 174 174 ASN ASN A . n 
A 1 175 PRO 175 175 175 PRO PRO A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 MET 178 178 178 MET MET A . n 
A 1 179 VAL 179 179 179 VAL VAL A . n 
A 1 180 TYR 180 180 180 TYR TYR A . n 
A 1 181 ARG 181 181 181 ARG ARG A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 GLU 183 183 183 GLU GLU A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 TYR 185 185 185 TYR TYR A . n 
A 1 186 ASP 186 186 186 ASP ASP A . n 
A 1 187 TYR 187 187 187 TYR TYR A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 SER 189 189 189 SER SER A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 GLU 194 194 194 GLU GLU A . n 
A 1 195 HIS 195 195 195 HIS HIS A . n 
A 1 196 GLN 196 196 196 GLN GLN A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 LYS 198 198 198 LYS LYS A . n 
A 1 199 ALA 199 199 199 ALA ALA A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 LYS 201 201 201 LYS LYS A . n 
A 1 202 ARG 202 202 202 ARG ARG A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 ASN 205 205 205 ASN ASN A . n 
A 1 206 THR 206 206 206 THR THR A . n 
A 1 207 ASP 207 207 207 ASP ASP A . n 
A 1 208 ILE 208 208 208 ILE ILE A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 VAL 210 210 210 VAL VAL A . n 
A 1 211 ASP 211 211 211 ASP ASP A . n 
A 1 212 PRO 212 212 212 PRO PRO A . n 
A 1 213 ASN 213 213 213 ASN ASN A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 VAL 215 215 215 VAL VAL A . n 
A 1 216 VAL 216 216 216 VAL VAL A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 THR 222 222 222 THR THR A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 PHE 224 224 224 PHE PHE A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ASP 226 226 226 ASP ASP A . n 
A 1 227 GLU 227 227 227 GLU GLU A . n 
A 1 228 SER 228 228 228 SER SER A . n 
A 1 229 GLY 229 229 229 GLY GLY A . n 
A 1 230 ASN 230 230 230 ASN ASN A . n 
A 1 231 ILE 231 231 231 ILE ILE A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 THR 237 237 237 THR THR A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 TYR 244 244 244 TYR TYR A . n 
A 1 245 ASP 245 245 245 ASP ASP A . n 
A 1 246 PHE 246 246 246 PHE PHE A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 THR 249 249 249 THR THR A . n 
A 1 250 TYR 250 250 250 TYR TYR A . n 
A 1 251 ILE 251 251 251 ILE ILE A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 PRO 253 253 253 PRO PRO A . n 
A 1 254 ILE 254 254 254 ILE ILE A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 CYS 260 260 260 CYS CYS A . n 
A 1 261 TRP 261 261 261 TRP TRP A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 ASN 263 263 263 ASN ASN A . n 
A 1 264 ASP 264 264 264 ASP ASP A . n 
A 1 265 PHE 265 265 265 PHE PHE A . n 
A 1 266 PRO 266 266 266 PRO PRO A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 ARG 269 269 269 ARG ARG A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 GLU 271 271 271 GLU GLU A . n 
A 1 272 ILE 272 272 272 ILE ILE A . n 
A 1 273 TYR 273 273 273 TYR TYR A . n 
A 1 274 THR 274 274 274 THR THR A . n 
A 1 275 ARG 275 275 275 ARG ARG A . n 
A 1 276 MET 276 276 276 MET MET A . n 
A 1 277 TYR 277 277 277 TYR TYR A . n 
A 1 278 PHE 278 278 278 PHE PHE A . n 
A 1 279 ASN 279 279 279 ASN ASN A . n 
A 1 280 HIS 280 280 280 HIS HIS A . n 
A 1 281 PRO 281 281 281 PRO PRO A . n 
A 1 282 GLY 282 282 282 GLY GLY A . n 
A 1 283 TYR 283 283 283 TYR TYR A . n 
A 1 284 ASP 284 284 284 ASP ASP A . n 
A 1 285 ASP 285 285 285 ASP ASP A . n 
A 1 286 TYR 286 286 286 TYR TYR A . n 
A 1 287 PRO 287 287 287 PRO PRO A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 VAL 289 289 289 VAL VAL A . n 
A 1 290 GLY 290 290 290 GLY GLY A . n 
A 1 291 ILE 291 291 291 ILE ILE A . n 
A 1 292 SER 292 292 292 SER SER A . n 
A 1 293 TRP 293 293 293 TRP TRP A . n 
A 1 294 GLU 294 294 294 GLU GLU A . n 
A 1 295 GLN 295 295 295 GLN GLN A . n 
A 1 296 ALA 296 296 296 ALA ALA A . n 
A 1 297 GLN 297 297 297 GLN GLN A . n 
A 1 298 ALA 298 298 298 ALA ALA A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 CYS 300 300 300 CYS CYS A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 TRP 302 302 302 TRP TRP A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 SER 304 304 304 SER SER A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 LYS 309 309 309 LYS LYS A . n 
A 1 310 GLY 310 310 310 GLY GLY A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 ARG 312 312 312 ARG ARG A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 PRO 314 314 314 PRO PRO A . n 
A 1 315 GLU 315 315 315 GLU GLU A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 GLN 317 317 317 GLN GLN A . n 
A 1 318 ILE 318 318 318 ILE ILE A . n 
A 1 319 MET 319 319 319 MET MET A . n 
A 1 320 ASP 320 320 320 ASP ASP A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 THR 326 326 326 THR THR A . n 
A 1 327 GLU 327 327 327 GLU GLU A . n 
A 1 328 ALA 328 328 328 ALA ALA A . n 
A 1 329 GLU 329 329 329 GLU GLU A . n 
A 1 330 TRP 330 330 330 TRP TRP A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 TYR 332 332 332 TYR TYR A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 ALA 334 334 334 ALA ALA A . n 
A 1 335 ARG 335 335 335 ARG ARG A . n 
A 1 336 MET 336 336 336 MET MET A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 ASP 338 338 338 ASP ASP A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 ASN 340 340 340 ASN ASN A . n 
A 1 341 ASN 341 341 341 ASN ASN A . n 
A 1 342 LYS 342 342 342 LYS LYS A . n 
A 1 343 TYR 343 343 343 TYR TYR A . n 
A 1 344 PRO 344 344 344 PRO PRO A . n 
A 1 345 TRP 345 345 345 TRP TRP A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 THR 347 347 347 THR THR A . n 
A 1 348 GLU 348 348 348 GLU GLU A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 LEU 350 350 350 LEU LEU A . n 
A 1 351 ARG 351 351 351 ARG ARG A . n 
A 1 352 THR 352 352 352 THR THR A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 ARG 354 354 354 ARG ARG A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 CYS 356 356 356 CYS CYS A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 LEU 358 358 358 LEU LEU A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 ASN 360 360 360 ASN ASN A . n 
A 1 361 PHE 361 361 361 PHE PHE A . n 
A 1 362 LYS 362 362 362 LYS LYS A . n 
A 1 363 PRO 363 363 363 PRO PRO A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 GLU 365 365 365 GLU GLU A . n 
A 1 366 GLY 366 366 366 GLY GLY A . n 
A 1 367 ASP 367 367 367 ASP ASP A . n 
A 1 368 TYR 368 368 368 TYR TYR A . n 
A 1 369 THR 369 369 369 THR THR A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 ASP 371 371 371 ASP ASP A . n 
A 1 372 GLY 372 372 372 GLY GLY A . n 
A 1 373 HIS 373 373 373 HIS HIS A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 PRO 376 376 376 PRO PRO A . n 
A 1 377 SER 377 377 377 SER SER A . n 
A 1 378 ARG 378 378 378 ARG ARG A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 SER 380 380 380 SER SER A . n 
A 1 381 SER 381 381 381 SER SER A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 SER 383 383 383 SER SER A . n 
A 1 384 PRO 384 384 384 PRO PRO A . n 
A 1 385 ASN 385 385 385 ASN ASN A . n 
A 1 386 ASP 386 386 386 ASP ASP A . n 
A 1 387 PHE 387 387 387 PHE PHE A . n 
A 1 388 GLY 388 388 388 GLY GLY A . n 
A 1 389 LEU 389 389 389 LEU LEU A . n 
A 1 390 TYR 390 390 390 TYR TYR A . n 
A 1 391 ASP 391 391 391 ASP ASP A . n 
A 1 392 MET 392 392 392 MET MET A . n 
A 1 393 ALA 393 393 393 ALA ALA A . n 
A 1 394 GLY 394 394 394 GLY GLY A . n 
A 1 395 ASN 395 395 395 ASN ASN A . n 
A 1 396 VAL 396 396 396 VAL VAL A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 GLU 398 398 398 GLU GLU A . n 
A 1 399 TRP 399 399 399 TRP TRP A . n 
A 1 400 THR 400 400 400 THR THR A . n 
A 1 401 SER 401 401 401 SER SER A . n 
A 1 402 THR 402 402 402 THR THR A . n 
A 1 403 ALA 403 403 403 ALA ALA A . n 
A 1 404 PHE 404 404 404 PHE PHE A . n 
A 1 405 SER 405 405 405 SER SER A . n 
A 1 406 GLU 406 406 406 GLU GLU A . n 
A 1 407 SER 407 407 407 SER SER A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 LEU 409 409 409 LEU LEU A . n 
A 1 410 LYS 410 410 410 LYS LYS A . n 
A 1 411 GLN 411 411 411 GLN GLN A . n 
A 1 412 MET 412 412 412 MET MET A . n 
A 1 413 SER 413 413 413 SER SER A . n 
A 1 414 ASP 414 414 414 ASP ASP A . n 
A 1 415 ILE 415 415 415 ILE ILE A . n 
A 1 416 ASN 416 416 416 ASN ASN A . n 
A 1 417 PRO 417 417 417 PRO PRO A . n 
A 1 418 GLU 418 418 418 GLU GLU A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 TYR 421 421 421 TYR TYR A . n 
A 1 422 LYS 422 422 422 LYS LYS A . n 
A 1 423 ALA 423 423 423 ALA ALA A . n 
A 1 424 ALA 424 424 424 ALA ALA A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 PRO 428 428 428 PRO PRO A . n 
A 1 429 TYR 429 429 429 TYR TYR A . n 
A 1 430 ILE 430 430 430 ILE ILE A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 LYS 432 432 432 LYS LYS A . n 
A 1 433 GLN 433 433 433 GLN GLN A . n 
A 1 434 LYS 434 434 434 LYS LYS A . n 
A 1 435 VAL 435 435 435 VAL VAL A . n 
A 1 436 VAL 436 436 436 VAL VAL A . n 
A 1 437 ARG 437 437 437 ARG ARG A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 GLY 439 439 439 GLY GLY A . n 
A 1 440 SER 440 440 440 SER SER A . n 
A 1 441 TRP 441 441 441 TRP TRP A . n 
A 1 442 LYS 442 442 442 LYS LYS A . n 
A 1 443 ASP 443 443 443 ASP ASP A . n 
A 1 444 VAL 444 444 444 VAL VAL A . n 
A 1 445 ALA 445 445 445 ALA ALA A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 PHE 447 447 447 PHE PHE A . n 
A 1 448 ILE 448 448 448 ILE ILE A . n 
A 1 449 ARG 449 449 449 ARG ARG A . n 
A 1 450 SER 450 450 450 SER SER A . n 
A 1 451 ALA 451 451 451 ALA ALA A . n 
A 1 452 THR 452 452 452 THR THR A . n 
A 1 453 ARG 453 453 453 ARG ARG A . n 
A 1 454 SER 454 454 454 SER SER A . n 
A 1 455 HIS 455 455 455 HIS HIS A . n 
A 1 456 GLU 456 456 456 GLU GLU A . n 
A 1 457 TYR 457 457 457 TYR TYR A . n 
A 1 458 GLN 458 458 458 GLN GLN A . n 
A 1 459 ASN 459 459 459 ASN ASN A . n 
A 1 460 VAL 460 460 460 VAL VAL A . n 
A 1 461 GLY 461 461 461 GLY GLY A . n 
A 1 462 ARG 462 462 462 ARG ARG A . n 
A 1 463 SER 463 463 463 SER SER A . n 
A 1 464 TYR 464 464 464 TYR TYR A . n 
A 1 465 ILE 465 465 465 ILE ILE A . n 
A 1 466 GLY 466 466 466 GLY GLY A . n 
A 1 467 PHE 467 467 467 PHE PHE A . n 
A 1 468 ARG 468 468 468 ARG ARG A . n 
A 1 469 CYS 469 469 469 CYS CYS A . n 
A 1 470 VAL 470 470 470 VAL VAL A . n 
A 1 471 ARG 471 471 471 ARG ARG A . n 
A 1 472 THR 472 472 472 THR THR A . n 
A 1 473 SER 473 473 473 SER SER A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 ALA 475 475 475 ALA ALA A . n 
A 1 476 PHE 476 476 476 PHE PHE A . n 
A 1 477 SER 477 477 ?   ?   ?   A . n 
A 1 478 SER 478 478 ?   ?   ?   A . n 
A 1 479 GLY 479 479 ?   ?   ?   A . n 
A 1 480 LYS 480 480 ?   ?   ?   A . n 
A 1 481 ALA 481 481 ?   ?   ?   A . n 
A 1 482 PRO 482 482 ?   ?   ?   A . n 
A 1 483 LYS 483 483 ?   ?   ?   A . n 
A 1 484 SER 484 484 ?   ?   ?   A . n 
A 1 485 SER 485 485 ?   ?   ?   A . n 
A 1 486 ARG 486 486 ?   ?   ?   A . n 
A 1 487 ARG 487 487 ?   ?   ?   A . n 
A 1 488 SER 488 488 ?   ?   ?   A . n 
A 1 489 THR 489 489 ?   ?   ?   A . n 
A 1 490 LYS 490 490 ?   ?   ?   A . n 
A 1 491 LYS 491 491 ?   ?   ?   A . n 
B 2 1   MET 1   -1  ?   ?   ?   B . n 
B 2 2   PHE 2   0   ?   ?   ?   B . n 
B 2 3   MET 3   1   ?   ?   ?   B . n 
B 2 4   LYS 4   2   ?   ?   ?   B . n 
B 2 5   VAL 5   3   ?   ?   ?   B . n 
B 2 6   PHE 6   4   ?   ?   ?   B . n 
B 2 7   LYS 7   5   ?   ?   ?   B . n 
B 2 8   ALA 8   6   ?   ?   ?   B . n 
B 2 9   VAL 9   7   ?   ?   ?   B . n 
B 2 10  ILE 10  8   ?   ?   ?   B . n 
B 2 11  GLY 11  9   ?   ?   ?   B . n 
B 2 12  ALA 12  10  ?   ?   ?   B . n 
B 2 13  ILE 13  11  ?   ?   ?   B . n 
B 2 14  LEU 14  12  ?   ?   ?   B . n 
B 2 15  ALA 15  13  ?   ?   ?   B . n 
B 2 16  ALA 16  14  ?   ?   ?   B . n 
B 2 17  THR 17  15  ?   ?   ?   B . n 
B 2 18  VAL 18  16  ?   ?   ?   B . n 
B 2 19  SER 19  17  ?   ?   ?   B . n 
B 2 20  ILE 20  18  ?   ?   ?   B . n 
B 2 21  SER 21  19  ?   ?   ?   B . n 
B 2 22  SER 22  20  ?   ?   ?   B . n 
B 2 23  VAL 23  21  ?   ?   ?   B . n 
B 2 24  ALA 24  22  ?   ?   ?   B . n 
B 2 25  GLN 25  23  ?   ?   ?   B . n 
B 2 26  GLU 26  24  ?   ?   ?   B . n 
B 2 27  ASN 27  25  ?   ?   ?   B . n 
B 2 28  THR 28  26  ?   ?   ?   B . n 
B 2 29  ASN 29  27  ?   ?   ?   B . n 
B 2 30  ASN 30  28  ?   ?   ?   B . n 
B 2 31  ARG 31  29  ?   ?   ?   B . n 
B 2 32  SER 32  30  ?   ?   ?   B . n 
B 2 33  PRO 33  31  ?   ?   ?   B . n 
B 2 34  GLN 34  32  ?   ?   ?   B . n 
B 2 35  VAL 35  33  ?   ?   ?   B . n 
B 2 36  GLY 36  34  ?   ?   ?   B . n 
B 2 37  ARG 37  35  ?   ?   ?   B . n 
B 2 38  ALA 38  36  ?   ?   ?   B . n 
B 2 39  PRO 39  37  ?   ?   ?   B . n 
B 2 40  ARG 40  38  ?   ?   ?   B . n 
B 2 41  ASN 41  39  ?   ?   ?   B . n 
B 2 42  THR 42  40  ?   ?   ?   B . n 
B 2 43  GLU 43  41  ?   ?   ?   B . n 
B 2 44  VAL 44  42  ?   ?   ?   B . n 
B 2 45  GLU 45  43  ?   ?   ?   B . n 
B 2 46  GLN 46  44  ?   ?   ?   B . n 
B 2 47  THR 47  45  ?   ?   ?   B . n 
B 2 48  THR 48  46  ?   ?   ?   B . n 
B 2 49  THR 49  47  47  THR THR B . n 
B 2 50  LEU 50  48  48  LEU LEU B . n 
B 2 51  SER 51  49  49  SER SER B . n 
B 2 52  ASN 52  50  50  ASN ASN B . n 
B 2 53  ARG 53  51  51  ARG ARG B . n 
B 2 54  ALA 54  52  52  ALA ALA B . n 
B 2 55  GLN 55  53  53  GLN GLN B . n 
B 2 56  GLU 56  54  54  GLU GLU B . n 
B 2 57  PHE 57  55  55  PHE PHE B . n 
B 2 58  ASN 58  56  56  ASN ASN B . n 
B 2 59  ARG 59  57  57  ARG ARG B . n 
B 2 60  ARG 60  58  58  ARG ARG B . n 
B 2 61  LEU 61  59  59  LEU LEU B . n 
B 2 62  THR 62  60  60  THR THR B . n 
B 2 63  GLN 63  61  61  GLN GLN B . n 
B 2 64  LYS 64  62  62  LYS LYS B . n 
B 2 65  THR 65  63  63  THR THR B . n 
B 2 66  ASP 66  64  64  ASP ASP B . n 
B 2 67  ASN 67  65  65  ASN ASN B . n 
B 2 68  ALA 68  66  66  ALA ALA B . n 
B 2 69  PRO 69  67  67  PRO PRO B . n 
B 2 70  TRP 70  68  68  TRP TRP B . n 
B 2 71  ARG 71  69  69  ARG ARG B . n 
B 2 72  ARG 72  70  70  ARG ARG B . n 
B 2 73  VAL 73  71  71  VAL VAL B . n 
B 2 74  VAL 74  72  72  VAL VAL B . n 
B 2 75  TYR 75  73  73  TYR TYR B . n 
B 2 76  ARG 76  74  74  ARG ARG B . n 
B 2 77  ARG 77  75  75  ARG ARG B . n 
B 2 78  VAL 78  76  76  VAL VAL B . n 
B 2 79  ASP 79  77  77  ASP ASP B . n 
B 2 80  LEU 80  78  78  LEU LEU B . n 
B 2 81  MET 81  79  79  MET MET B . n 
B 2 82  GLU 82  80  80  GLU GLU B . n 
B 2 83  GLU 83  81  81  GLU GLU B . n 
B 2 84  SER 84  82  82  SER SER B . n 
B 2 85  ASN 85  83  83  ASN ASN B . n 
B 2 86  ALA 86  84  84  ALA ALA B . n 
B 2 87  VAL 87  85  85  VAL VAL B . n 
B 2 88  LEU 88  86  86  LEU LEU B . n 
B 2 89  TYR 89  87  87  TYR TYR B . n 
B 2 90  TYR 90  88  88  TYR TYR B . n 
B 2 91  PRO 91  89  89  PRO PRO B . n 
B 2 92  PRO 92  90  90  PRO PRO B . n 
B 2 93  ARG 93  91  91  ARG ARG B . n 
B 2 94  PRO 94  92  92  PRO PRO B . n 
B 2 95  ILE 95  93  93  ILE ILE B . n 
B 2 96  GLY 96  94  94  GLY GLY B . n 
B 2 97  ASP 97  95  95  ASP ASP B . n 
B 2 98  ARG 98  96  96  ARG ARG B . n 
B 2 99  LYS 99  97  97  LYS LYS B . n 
B 2 100 ASN 100 98  98  ASN ASN B . n 
B 2 101 LEU 101 99  99  LEU LEU B . n 
B 2 102 PHE 102 100 100 PHE PHE B . n 
B 2 103 SER 103 101 101 SER SER B . n 
B 2 104 THR 104 102 102 THR THR B . n 
B 2 105 ILE 105 103 103 ILE ILE B . n 
B 2 106 PHE 106 104 104 PHE PHE B . n 
B 2 107 GLY 107 105 105 GLY GLY B . n 
B 2 108 LEU 108 106 106 LEU LEU B . n 
B 2 109 ILE 109 107 107 ILE ILE B . n 
B 2 110 ASN 110 108 108 ASN ASN B . n 
B 2 111 SER 111 109 109 SER SER B . n 
B 2 112 ASN 112 110 110 ASN ASN B . n 
B 2 113 SER 113 111 111 SER SER B . n 
B 2 114 LEU 114 112 112 LEU LEU B . n 
B 2 115 ASP 115 113 113 ASP ASP B . n 
B 2 116 VAL 116 114 114 VAL VAL B . n 
B 2 117 TYR 117 115 115 TYR TYR B . n 
B 2 118 GLU 118 116 116 GLU GLU B . n 
B 2 119 TYR 119 117 117 TYR TYR B . n 
B 2 120 LEU 120 118 118 LEU LEU B . n 
B 2 121 ASP 121 119 119 ASP ASP B . n 
B 2 122 GLY 122 120 120 GLY GLY B . n 
B 2 123 PHE 123 121 121 PHE PHE B . n 
B 2 124 GLU 124 122 122 GLU GLU B . n 
B 2 125 ALA 125 123 123 ALA ALA B . n 
B 2 126 PHE 126 124 124 PHE PHE B . n 
B 2 127 THR 127 125 125 THR THR B . n 
B 2 128 ASP 128 126 126 ASP ASP B . n 
B 2 129 GLN 129 127 127 GLN GLN B . n 
B 2 130 TYR 130 128 128 TYR TYR B . n 
B 2 131 LYS 131 129 129 LYS LYS B . n 
B 2 132 ILE 132 130 130 ILE ILE B . n 
B 2 133 LYS 133 131 131 LYS LYS B . n 
B 2 134 PHE 134 132 132 PHE PHE B . n 
B 2 135 GLN 135 133 133 GLN GLN B . n 
B 2 136 GLU 136 134 134 GLU GLU B . n 
B 2 137 PHE 137 135 135 PHE PHE B . n 
B 2 138 LEU 138 136 136 LEU LEU B . n 
B 2 139 ASP 139 137 137 ASP ASP B . n 
B 2 140 ARG 140 138 138 ARG ARG B . n 
B 2 141 PHE 141 139 139 PHE PHE B . n 
B 2 142 GLY 142 140 140 GLY GLY B . n 
B 2 143 ILE 143 141 141 ILE ILE B . n 
B 2 144 TYR 144 142 142 TYR TYR B . n 
B 2 145 TYR 145 143 143 TYR TYR B . n 
B 2 146 GLN 146 144 144 GLN GLN B . n 
B 2 147 PRO 147 145 145 PRO PRO B . n 
B 2 148 SER 148 146 146 SER SER B . n 
B 2 149 THR 149 147 147 THR THR B . n 
B 2 150 ASN 150 148 148 ASN ASN B . n 
B 2 151 LYS 151 149 149 LYS LYS B . n 
B 2 152 ASN 152 150 150 ASN ASN B . n 
B 2 153 ALA 153 151 151 ALA ALA B . n 
B 2 154 GLU 154 152 152 GLU GLU B . n 
B 2 155 LEU 155 153 153 LEU LEU B . n 
B 2 156 PHE 156 154 154 PHE PHE B . n 
B 2 157 LYS 157 155 155 LYS LYS B . n 
B 2 158 VAL 158 156 156 VAL VAL B . n 
B 2 159 ALA 159 157 157 ALA ALA B . n 
B 2 160 ASP 160 158 158 ASP ASP B . n 
B 2 161 SER 161 159 159 SER SER B . n 
B 2 162 ASP 162 160 160 ASP ASP B . n 
B 2 163 ILE 163 161 161 ILE ILE B . n 
B 2 164 PRO 164 162 162 PRO PRO B . n 
B 2 165 SER 165 163 163 SER SER B . n 
B 2 166 ALA 166 164 164 ALA ALA B . n 
B 2 167 GLU 167 165 165 GLU GLU B . n 
B 2 168 VAL 168 166 166 VAL VAL B . n 
B 2 169 LYS 169 167 167 LYS LYS B . n 
B 2 170 ALA 170 168 168 ALA ALA B . n 
B 2 171 TYR 171 169 169 TYR TYR B . n 
B 2 172 TYR 172 170 170 TYR TYR B . n 
B 2 173 VAL 173 171 171 VAL VAL B . n 
B 2 174 LYS 174 172 172 LYS LYS B . n 
B 2 175 GLU 175 173 173 GLU GLU B . n 
B 2 176 GLU 176 174 174 GLU GLU B . n 
B 2 177 TRP 177 175 175 TRP TRP B . n 
B 2 178 TYR 178 176 176 TYR TYR B . n 
B 2 179 PHE 179 177 177 PHE PHE B . n 
B 2 180 THR 180 178 178 THR THR B . n 
B 2 181 PRO 181 179 179 PRO PRO B . n 
B 2 182 THR 182 180 180 THR THR B . n 
B 2 183 ASN 183 181 181 ASN ASN B . n 
B 2 184 SER 184 182 182 SER SER B . n 
B 2 185 ASP 185 183 183 ASP ASP B . n 
B 2 186 VAL 186 184 184 VAL VAL B . n 
B 2 187 ASP 187 185 185 ASP ASP B . n 
B 2 188 ILE 188 186 186 ILE ILE B . n 
B 2 189 LYS 189 187 187 LYS LYS B . n 
B 2 190 ILE 190 188 188 ILE ILE B . n 
B 2 191 GLN 191 189 189 GLN GLN B . n 
B 2 192 ALA 192 190 190 ALA ALA B . n 
B 2 193 ILE 193 191 191 ILE ILE B . n 
B 2 194 CYS 194 192 192 CYS CYS B . n 
B 2 195 PRO 195 193 193 PRO PRO B . n 
B 2 196 ILE 196 194 194 ILE ILE B . n 
B 2 197 MET 197 195 195 MET MET B . n 
B 2 198 THR 198 196 196 THR THR B . n 
B 2 199 GLY 199 197 197 GLY GLY B . n 
B 2 200 GLN 200 198 198 GLN GLN B . n 
B 2 201 ASP 201 199 199 ASP ASP B . n 
B 2 202 GLU 202 200 200 GLU GLU B . n 
B 2 203 PHE 203 201 201 PHE PHE B . n 
B 2 204 GLY 204 202 202 GLY GLY B . n 
B 2 205 GLU 205 203 203 GLU GLU B . n 
B 2 206 VAL 206 204 204 VAL VAL B . n 
B 2 207 ARG 207 205 205 ARG ARG B . n 
B 2 208 ASN 208 206 206 ASN ASN B . n 
B 2 209 GLN 209 207 207 GLN GLN B . n 
B 2 210 PRO 210 208 208 PRO PRO B . n 
B 2 211 LEU 211 209 209 LEU LEU B . n 
B 2 212 PHE 212 210 210 PHE PHE B . n 
B 2 213 TRP 213 211 211 TRP TRP B . n 
B 2 214 ILE 214 212 212 ILE ILE B . n 
B 2 215 PRO 215 213 213 PRO PRO B . n 
B 2 216 TYR 216 214 214 TYR TYR B . n 
B 2 217 GLU 217 215 215 GLU GLU B . n 
B 2 218 ASN 218 216 216 ASN ASN B . n 
B 2 219 ILE 219 217 217 ILE ILE B . n 
B 2 220 ARG 220 218 218 ARG ARG B . n 
B 2 221 PRO 221 219 219 PRO PRO B . n 
B 2 222 TYR 222 220 220 TYR TYR B . n 
B 2 223 ILE 223 221 221 ILE ILE B . n 
B 2 224 ALA 224 222 222 ALA ALA B . n 
B 2 225 ARG 225 223 223 ARG ARG B . n 
B 2 226 GLU 226 224 224 GLU GLU B . n 
B 2 227 ARG 227 225 225 ARG ARG B . n 
B 2 228 VAL 228 226 226 VAL VAL B . n 
B 2 229 MET 229 227 227 MET MET B . n 
B 2 230 LEU 230 228 228 LEU LEU B . n 
B 2 231 SER 231 229 229 SER SER B . n 
B 2 232 SER 232 230 230 SER SER B . n 
B 2 233 LEU 233 231 231 LEU LEU B . n 
B 2 234 ASN 234 232 232 ASN ASN B . n 
B 2 235 ASN 235 233 233 ASN ASN B . n 
B 2 236 THR 236 234 234 THR THR B . n 
B 2 237 ARG 237 235 235 ARG ARG B . n 
B 2 238 ASN 238 236 236 ASN ASN B . n 
B 2 239 SER 239 237 237 SER SER B . n 
B 2 240 THR 240 238 238 THR THR B . n 
B 2 241 ILE 241 239 239 ILE ILE B . n 
B 2 242 ASP 242 240 240 ASP ASP B . n 
B 2 243 ASP 243 241 241 ASP ASP B . n 
B 2 244 PHE 244 242 242 PHE PHE B . n 
B 2 245 PHE 245 243 243 PHE PHE B . n 
B 2 246 ARG 246 244 244 ARG ARG B . n 
B 2 247 LEU 247 245 245 LEU LEU B . n 
B 2 248 ASN 248 246 246 ASN ASN B . n 
B 2 249 LEU 249 247 247 LEU LEU B . n 
B 2 250 TYR 250 248 248 TYR TYR B . n 
B 2 251 LYS 251 249 249 LYS LYS B . n 
B 2 252 GLY 252 250 250 GLY GLY B . n 
B 2 253 ASP 253 251 251 ASP ASP B . n 
B 2 254 ILE 254 252 252 ILE ILE B . n 
B 2 255 VAL 255 253 253 VAL VAL B . n 
B 2 256 LYS 256 254 254 LYS LYS B . n 
B 2 257 THR 257 255 255 THR THR B . n 
B 2 258 GLU 258 256 256 GLU GLU B . n 
B 2 259 ASN 259 257 257 ASN ASN B . n 
B 2 260 LEU 260 258 258 LEU LEU B . n 
B 2 261 HIS 261 259 259 HIS HIS B . n 
B 2 262 ASN 262 260 260 ASN ASN B . n 
B 2 263 ARG 263 261 261 ARG ARG B . n 
B 2 264 ALA 264 262 262 ALA ALA B . n 
B 2 265 LEU 265 263 263 LEU LEU B . n 
B 2 266 ALA 266 264 264 ALA ALA B . n 
B 2 267 GLU 267 265 265 GLU GLU B . n 
B 2 268 TYR 268 266 266 TYR TYR B . n 
B 2 269 CYS 269 267 267 CYS CYS B . n 
B 2 270 PRO 270 268 268 PRO PRO B . n 
B 2 271 THR 271 269 269 THR THR B . n 
B 2 272 PRO 272 270 270 PRO PRO B . n 
B 2 273 ASP 273 271 271 ASP ASP B . n 
B 2 274 SER 274 272 272 SER SER B . n 
B 2 275 MET 275 273 273 MET MET B . n 
B 2 276 LYS 276 274 274 LYS LYS B . n 
B 2 277 MET 277 275 275 MET MET B . n 
B 2 278 GLU 278 276 276 GLU GLU B . n 
B 2 279 SER 279 277 277 SER SER B . n 
B 2 280 LYS 280 278 278 LYS LYS B . n 
B 2 281 ARG 281 279 279 ARG ARG B . n 
B 2 282 ILE 282 280 280 ILE ILE B . n 
B 2 283 ASP 283 281 281 ASP ASP B . n 
B 2 284 LYS 284 282 282 LYS LYS B . n 
B 2 285 GLU 285 283 283 GLU GLU B . n 
B 2 286 LEU 286 284 284 LEU LEU B . n 
B 2 287 GLN 287 285 285 GLN GLN B . n 
B 2 288 GLY 288 286 286 GLY GLY B . n 
B 2 289 PHE 289 287 287 PHE PHE B . n 
B 2 290 ARG 290 288 288 ARG ARG B . n 
B 2 291 ASP 291 289 289 ASP ASP B . n 
B 2 292 GLY 292 290 290 GLY GLY B . n 
B 2 293 LEU 293 291 291 LEU LEU B . n 
B 2 294 PHE 294 292 292 PHE PHE B . n 
B 2 295 VAL 295 293 293 VAL VAL B . n 
B 2 296 THR 296 294 294 THR THR B . n 
B 2 297 GLN 297 295 295 GLN GLN B . n 
B 2 298 ASP 298 296 296 ASP ASP B . n 
B 2 299 THR 299 297 297 THR THR B . n 
B 2 300 THR 300 298 298 THR THR B . n 
B 2 301 TRP 301 299 299 TRP TRP B . n 
B 2 302 MET 302 300 ?   ?   ?   B . n 
B 2 303 LYS 303 301 ?   ?   ?   B . n 
B 2 304 GLN 304 302 ?   ?   ?   B . n 
B 2 305 ALA 305 303 ?   ?   ?   B . n 
B 2 306 GLU 306 304 ?   ?   ?   B . n 
B 2 307 THR 307 305 ?   ?   ?   B . n 
B 2 308 LYS 308 306 ?   ?   ?   B . n 
B 2 309 LYS 309 307 ?   ?   ?   B . n 
B 2 310 SER 310 308 ?   ?   ?   B . n 
B 2 311 LYS 311 309 ?   ?   ?   B . n 
B 2 312 GLY 312 310 ?   ?   ?   B . n 
B 2 313 LYS 313 311 ?   ?   ?   B . n 
B 2 314 LYS 314 312 ?   ?   ?   B . n 
B 2 315 LEU 315 313 ?   ?   ?   B . n 
B 2 316 GLU 316 314 ?   ?   ?   B . n 
B 2 317 LYS 317 315 ?   ?   ?   B . n 
B 2 318 ALA 318 316 ?   ?   ?   B . n 
B 2 319 ARG 319 317 ?   ?   ?   B . n 
B 2 320 GLY 320 318 ?   ?   ?   B . n 
B 2 321 LYS 321 319 ?   ?   ?   B . n 
B 2 322 ASN 322 320 ?   ?   ?   B . n 
B 2 323 ILE 323 321 ?   ?   ?   B . n 
B 2 324 THR 324 322 ?   ?   ?   B . n 
B 2 325 SER 325 323 ?   ?   ?   B . n 
B 2 326 ARG 326 324 ?   ?   ?   B . n 
B 2 327 THR 327 325 ?   ?   ?   B . n 
B 2 328 ARG 328 326 ?   ?   ?   B . n 
B 2 329 GLY 329 327 ?   ?   ?   B . n 
B 2 330 GLN 330 328 ?   ?   ?   B . n 
B 2 331 GLY 331 329 ?   ?   ?   B . n 
B 2 332 GLU 332 330 ?   ?   ?   B . n 
B 2 333 GLY 333 331 ?   ?   ?   B . n 
B 2 334 ALA 334 332 ?   ?   ?   B . n 
B 2 335 ALA 335 333 ?   ?   ?   B . n 
B 2 336 GLU 336 334 ?   ?   ?   B . n 
B 2 337 THR 337 335 ?   ?   ?   B . n 
B 2 338 GLU 338 336 ?   ?   ?   B . n 
B 2 339 ALA 339 337 ?   ?   ?   B . n 
B 2 340 VAL 340 338 ?   ?   ?   B . n 
B 2 341 GLU 341 339 ?   ?   ?   B . n 
B 2 342 PRO 342 340 ?   ?   ?   B . n 
B 2 343 LYS 343 341 ?   ?   ?   B . n 
B 2 344 LYS 344 342 ?   ?   ?   B . n 
B 2 345 GLN 345 343 ?   ?   ?   B . n 
B 2 346 LYS 346 344 ?   ?   ?   B . n 
B 2 347 ALA 347 345 ?   ?   ?   B . n 
B 2 348 SER 348 346 ?   ?   ?   B . n 
B 2 349 LYS 349 347 ?   ?   ?   B . n 
B 2 350 ASN 350 348 ?   ?   ?   B . n 
B 2 351 LYS 351 349 ?   ?   ?   B . n 
B 2 352 ALA 352 350 ?   ?   ?   B . n 
B 2 353 ALA 353 351 ?   ?   ?   B . n 
B 2 354 THR 354 352 ?   ?   ?   B . n 
B 2 355 ARG 355 353 ?   ?   ?   B . n 
B 2 356 SER 356 354 ?   ?   ?   B . n 
B 2 357 VAL 357 355 ?   ?   ?   B . n 
B 2 358 ARG 358 356 ?   ?   ?   B . n 
B 2 359 ARG 359 357 ?   ?   ?   B . n 
B 2 360 ARG 360 358 ?   ?   ?   B . n 
B 2 361 LYS 361 359 ?   ?   ?   B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   CYS 2   2   ?   ?   ?   C . n 
C 1 3   ARG 3   3   ?   ?   ?   C . n 
C 1 4   LYS 4   4   ?   ?   ?   C . n 
C 1 5   ASN 5   5   ?   ?   ?   C . n 
C 1 6   ARG 6   6   ?   ?   ?   C . n 
C 1 7   PHE 7   7   ?   ?   ?   C . n 
C 1 8   PHE 8   8   ?   ?   ?   C . n 
C 1 9   ALA 9   9   ?   ?   ?   C . n 
C 1 10  LEU 10  10  ?   ?   ?   C . n 
C 1 11  ALA 11  11  ?   ?   ?   C . n 
C 1 12  GLY 12  12  ?   ?   ?   C . n 
C 1 13  PHE 13  13  ?   ?   ?   C . n 
C 1 14  PHE 14  14  ?   ?   ?   C . n 
C 1 15  LEU 15  15  ?   ?   ?   C . n 
C 1 16  PHE 16  16  ?   ?   ?   C . n 
C 1 17  GLY 17  17  ?   ?   ?   C . n 
C 1 18  VAL 18  18  ?   ?   ?   C . n 
C 1 19  PHE 19  19  ?   ?   ?   C . n 
C 1 20  THR 20  20  ?   ?   ?   C . n 
C 1 21  ILE 21  21  ?   ?   ?   C . n 
C 1 22  SER 22  22  ?   ?   ?   C . n 
C 1 23  SER 23  23  ?   ?   ?   C . n 
C 1 24  CYS 24  24  ?   ?   ?   C . n 
C 1 25  GLY 25  25  ?   ?   ?   C . n 
C 1 26  SER 26  26  ?   ?   ?   C . n 
C 1 27  SER 27  27  ?   ?   ?   C . n 
C 1 28  LYS 28  28  ?   ?   ?   C . n 
C 1 29  ARG 29  29  ?   ?   ?   C . n 
C 1 30  ALA 30  30  ?   ?   ?   C . n 
C 1 31  VAL 31  31  ?   ?   ?   C . n 
C 1 32  GLY 32  32  32  GLY GLY C . n 
C 1 33  GLY 33  33  33  GLY GLY C . n 
C 1 34  GLU 34  34  34  GLU GLU C . n 
C 1 35  LEU 35  35  35  LEU LEU C . n 
C 1 36  THR 36  36  36  THR THR C . n 
C 1 37  GLY 37  37  37  GLY GLY C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  LYS 39  39  39  LYS LYS C . n 
C 1 40  LEU 40  40  40  LEU LEU C . n 
C 1 41  SER 41  41  41  SER SER C . n 
C 1 42  SER 42  42  42  SER SER C . n 
C 1 43  TRP 43  43  43  TRP TRP C . n 
C 1 44  ASN 44  44  44  ASN ASN C . n 
C 1 45  GLU 45  45  45  GLU GLU C . n 
C 1 46  PRO 46  46  46  PRO PRO C . n 
C 1 47  SER 47  47  47  SER SER C . n 
C 1 48  PRO 48  48  48  PRO PRO C . n 
C 1 49  PHE 49  49  49  PHE PHE C . n 
C 1 50  GLY 50  50  50  GLY GLY C . n 
C 1 51  MET 51  51  51  MET MET C . n 
C 1 52  ILE 52  52  52  ILE ILE C . n 
C 1 53  GLN 53  53  53  GLN GLN C . n 
C 1 54  VAL 54  54  54  VAL VAL C . n 
C 1 55  PRO 55  55  55  PRO PRO C . n 
C 1 56  ARG 56  56  56  ARG ARG C . n 
C 1 57  GLY 57  57  57  GLY GLY C . n 
C 1 58  SER 58  58  58  SER SER C . n 
C 1 59  ILE 59  59  59  ILE ILE C . n 
C 1 60  VAL 60  60  60  VAL VAL C . n 
C 1 61  LEU 61  61  61  LEU LEU C . n 
C 1 62  GLY 62  62  62  GLY GLY C . n 
C 1 63  ASN 63  63  63  ASN ASN C . n 
C 1 64  LYS 64  64  64  LYS LYS C . n 
C 1 65  GLU 65  65  65  GLU GLU C . n 
C 1 66  ALA 66  66  66  ALA ALA C . n 
C 1 67  ASP 67  67  67  ASP ASP C . n 
C 1 68  SER 68  68  68  SER SER C . n 
C 1 69  LEU 69  69  69  LEU LEU C . n 
C 1 70  TRP 70  70  70  TRP TRP C . n 
C 1 71  GLY 71  71  71  GLY GLY C . n 
C 1 72  ILE 72  72  72  ILE ILE C . n 
C 1 73  PRO 73  73  73  PRO PRO C . n 
C 1 74  ALA 74  74  74  ALA ALA C . n 
C 1 75  GLU 75  75  75  GLU GLU C . n 
C 1 76  SER 76  76  76  SER SER C . n 
C 1 77  ARG 77  77  77  ARG ARG C . n 
C 1 78  PRO 78  78  78  PRO PRO C . n 
C 1 79  ILE 79  79  79  ILE ILE C . n 
C 1 80  SER 80  80  80  SER SER C . n 
C 1 81  VAL 81  81  81  VAL VAL C . n 
C 1 82  ASP 82  82  82  ASP ASP C . n 
C 1 83  ALA 83  83  83  ALA ALA C . n 
C 1 84  PHE 84  84  84  PHE PHE C . n 
C 1 85  TRP 85  85  85  TRP TRP C . n 
C 1 86  MET 86  86  86  MET MET C . n 
C 1 87  ASP 87  87  87  ASP ASP C . n 
C 1 88  ARG 88  88  88  ARG ARG C . n 
C 1 89  THR 89  89  89  THR THR C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  ILE 91  91  91  ILE ILE C . n 
C 1 92  THR 92  92  92  THR THR C . n 
C 1 93  ASN 93  93  93  ASN ASN C . n 
C 1 94  ALA 94  94  94  ALA ALA C . n 
C 1 95  GLN 95  95  95  GLN GLN C . n 
C 1 96  TYR 96  96  96  TYR TYR C . n 
C 1 97  ARG 97  97  97  ARG ARG C . n 
C 1 98  GLN 98  98  98  GLN GLN C . n 
C 1 99  PHE 99  99  99  PHE PHE C . n 
C 1 100 VAL 100 100 100 VAL VAL C . n 
C 1 101 TYR 101 101 101 TYR TYR C . n 
C 1 102 TYR 102 102 102 TYR TYR C . n 
C 1 103 VAL 103 103 103 VAL VAL C . n 
C 1 104 ARG 104 104 104 ARG ARG C . n 
C 1 105 ASP 105 105 105 ASP ASP C . n 
C 1 106 SER 106 106 106 SER SER C . n 
C 1 107 ILE 107 107 107 ILE ILE C . n 
C 1 108 ILE 108 108 108 ILE ILE C . n 
C 1 109 ARG 109 109 109 ARG ARG C . n 
C 1 110 GLU 110 110 110 GLU GLU C . n 
C 1 111 ARG 111 111 111 ARG ARG C . n 
C 1 112 LEU 112 112 112 LEU LEU C . n 
C 1 113 ALA 113 113 113 ALA ALA C . n 
C 1 114 ASP 114 114 114 ASP ASP C . n 
C 1 115 PRO 115 115 115 PRO PRO C . n 
C 1 116 ALA 116 116 116 ALA ALA C . n 
C 1 117 TYR 117 117 117 TYR TYR C . n 
C 1 118 GLY 118 118 118 GLY GLY C . n 
C 1 119 GLY 119 119 119 GLY GLY C . n 
C 1 120 ASN 120 120 120 ASN ASN C . n 
C 1 121 GLU 121 121 121 GLU GLU C . n 
C 1 122 GLU 122 122 122 GLU GLU C . n 
C 1 123 TYR 123 123 123 TYR TYR C . n 
C 1 124 LYS 124 124 124 LYS LYS C . n 
C 1 125 ILE 125 125 125 ILE ILE C . n 
C 1 126 THR 126 126 126 THR THR C . n 
C 1 127 GLU 127 127 127 GLU GLU C . n 
C 1 128 ASN 128 128 128 ASN ASN C . n 
C 1 129 LYS 129 129 129 LYS LYS C . n 
C 1 130 PHE 130 130 130 PHE PHE C . n 
C 1 131 GLY 131 131 131 GLY GLY C . n 
C 1 132 GLU 132 132 132 GLU GLU C . n 
C 1 133 PRO 133 133 133 PRO PRO C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 THR 135 135 135 THR THR C . n 
C 1 136 PRO 136 136 136 PRO PRO C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 LEU 138 138 138 LEU LEU C . n 
C 1 139 ASP 139 139 139 ASP ASP C . n 
C 1 140 TRP 140 140 140 TRP TRP C . n 
C 1 141 SER 141 141 141 SER SER C . n 
C 1 142 LYS 142 142 142 LYS LYS C . n 
C 1 143 PRO 143 143 143 PRO PRO C . n 
C 1 144 ILE 144 144 144 ILE ILE C . n 
C 1 145 PRO 145 145 145 PRO PRO C . n 
C 1 146 SER 146 146 146 SER SER C . n 
C 1 147 GLU 147 147 147 GLU GLU C . n 
C 1 148 LYS 148 148 148 LYS LYS C . n 
C 1 149 ARG 149 149 149 ARG ARG C . n 
C 1 150 ALA 150 150 150 ALA ALA C . n 
C 1 151 THR 151 151 151 THR THR C . n 
C 1 152 GLU 152 152 152 GLU GLU C . n 
C 1 153 GLU 153 153 153 GLU GLU C . n 
C 1 154 GLU 154 154 154 GLU GLU C . n 
C 1 155 ILE 155 155 155 ILE ILE C . n 
C 1 156 ALA 156 156 156 ALA ALA C . n 
C 1 157 ALA 157 157 157 ALA ALA C . n 
C 1 158 ILE 158 158 158 ILE ILE C . n 
C 1 159 ASN 159 159 159 ASN ASN C . n 
C 1 160 SER 160 160 160 SER SER C . n 
C 1 161 VAL 161 161 161 VAL VAL C . n 
C 1 162 TYR 162 162 162 TYR TYR C . n 
C 1 163 TYR 163 163 163 TYR TYR C . n 
C 1 164 THR 164 164 164 THR THR C . n 
C 1 165 ASN 165 165 165 ASN ASN C . n 
C 1 166 PRO 166 166 166 PRO PRO C . n 
C 1 167 VAL 167 167 167 VAL VAL C . n 
C 1 168 THR 168 168 168 THR THR C . n 
C 1 169 HIS 169 169 169 HIS HIS C . n 
C 1 170 ASP 170 170 170 ASP ASP C . n 
C 1 171 ARG 171 171 171 ARG ARG C . n 
C 1 172 LYS 172 172 172 LYS LYS C . n 
C 1 173 LEU 173 173 173 LEU LEU C . n 
C 1 174 ASN 174 174 174 ASN ASN C . n 
C 1 175 PRO 175 175 175 PRO PRO C . n 
C 1 176 ASP 176 176 176 ASP ASP C . n 
C 1 177 GLN 177 177 177 GLN GLN C . n 
C 1 178 MET 178 178 178 MET MET C . n 
C 1 179 VAL 179 179 179 VAL VAL C . n 
C 1 180 TYR 180 180 180 TYR TYR C . n 
C 1 181 ARG 181 181 181 ARG ARG C . n 
C 1 182 TYR 182 182 182 TYR TYR C . n 
C 1 183 GLU 183 183 183 GLU GLU C . n 
C 1 184 VAL 184 184 184 VAL VAL C . n 
C 1 185 TYR 185 185 185 TYR TYR C . n 
C 1 186 ASP 186 186 186 ASP ASP C . n 
C 1 187 TYR 187 187 187 TYR TYR C . n 
C 1 188 ARG 188 188 188 ARG ARG C . n 
C 1 189 SER 189 189 189 SER SER C . n 
C 1 190 ALA 190 190 190 ALA ALA C . n 
C 1 191 ALA 191 191 191 ALA ALA C . n 
C 1 192 LEU 192 192 192 LEU LEU C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 GLU 194 194 194 GLU GLU C . n 
C 1 195 HIS 195 195 195 HIS HIS C . n 
C 1 196 GLN 196 196 196 GLN GLN C . n 
C 1 197 LEU 197 197 197 LEU LEU C . n 
C 1 198 LYS 198 198 198 LYS LYS C . n 
C 1 199 ALA 199 199 199 ALA ALA C . n 
C 1 200 ALA 200 200 200 ALA ALA C . n 
C 1 201 LYS 201 201 201 LYS LYS C . n 
C 1 202 ARG 202 202 202 ARG ARG C . n 
C 1 203 ASN 203 203 203 ASN ASN C . n 
C 1 204 LEU 204 204 204 LEU LEU C . n 
C 1 205 ASN 205 205 205 ASN ASN C . n 
C 1 206 THR 206 206 206 THR THR C . n 
C 1 207 ASP 207 207 207 ASP ASP C . n 
C 1 208 ILE 208 208 208 ILE ILE C . n 
C 1 209 LYS 209 209 209 LYS LYS C . n 
C 1 210 VAL 210 210 210 VAL VAL C . n 
C 1 211 ASP 211 211 211 ASP ASP C . n 
C 1 212 PRO 212 212 212 PRO PRO C . n 
C 1 213 ASN 213 213 213 ASN ASN C . n 
C 1 214 ALA 214 214 214 ALA ALA C . n 
C 1 215 VAL 215 215 215 VAL VAL C . n 
C 1 216 VAL 216 216 216 VAL VAL C . n 
C 1 217 MET 217 217 217 MET MET C . n 
C 1 218 ILE 218 218 218 ILE ILE C . n 
C 1 219 SER 219 219 219 SER SER C . n 
C 1 220 LYS 220 220 220 LYS LYS C . n 
C 1 221 ASP 221 221 221 ASP ASP C . n 
C 1 222 THR 222 222 222 THR THR C . n 
C 1 223 ALA 223 223 223 ALA ALA C . n 
C 1 224 PHE 224 224 224 PHE PHE C . n 
C 1 225 VAL 225 225 225 VAL VAL C . n 
C 1 226 ASP 226 226 226 ASP ASP C . n 
C 1 227 GLU 227 227 227 GLU GLU C . n 
C 1 228 SER 228 228 228 SER SER C . n 
C 1 229 GLY 229 229 229 GLY GLY C . n 
C 1 230 ASN 230 230 230 ASN ASN C . n 
C 1 231 ILE 231 231 231 ILE ILE C . n 
C 1 232 ILE 232 232 232 ILE ILE C . n 
C 1 233 SER 233 233 233 SER SER C . n 
C 1 234 GLU 234 234 234 GLU GLU C . n 
C 1 235 THR 235 235 235 THR THR C . n 
C 1 236 ILE 236 236 236 ILE ILE C . n 
C 1 237 THR 237 237 237 THR THR C . n 
C 1 238 ARG 238 238 238 ARG ARG C . n 
C 1 239 PRO 239 239 239 PRO PRO C . n 
C 1 240 LEU 240 240 240 LEU LEU C . n 
C 1 241 SER 241 241 241 SER SER C . n 
C 1 242 SER 242 242 242 SER SER C . n 
C 1 243 GLU 243 243 243 GLU GLU C . n 
C 1 244 TYR 244 244 244 TYR TYR C . n 
C 1 245 ASP 245 245 245 ASP ASP C . n 
C 1 246 PHE 246 246 246 PHE PHE C . n 
C 1 247 LEU 247 247 247 LEU LEU C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 THR 249 249 249 THR THR C . n 
C 1 250 TYR 250 250 250 TYR TYR C . n 
C 1 251 ILE 251 251 251 ILE ILE C . n 
C 1 252 VAL 252 252 252 VAL VAL C . n 
C 1 253 PRO 253 253 253 PRO PRO C . n 
C 1 254 ILE 254 254 254 ILE ILE C . n 
C 1 255 TYR 255 255 255 TYR TYR C . n 
C 1 256 PRO 256 256 256 PRO PRO C . n 
C 1 257 ASP 257 257 257 ASP ASP C . n 
C 1 258 GLU 258 258 258 GLU GLU C . n 
C 1 259 THR 259 259 259 THR THR C . n 
C 1 260 CYS 260 260 260 CYS CYS C . n 
C 1 261 TRP 261 261 261 TRP TRP C . n 
C 1 262 VAL 262 262 262 VAL VAL C . n 
C 1 263 ASN 263 263 263 ASN ASN C . n 
C 1 264 ASP 264 264 264 ASP ASP C . n 
C 1 265 PHE 265 265 265 PHE PHE C . n 
C 1 266 PRO 266 266 266 PRO PRO C . n 
C 1 267 ASN 267 267 267 ASN ASN C . n 
C 1 268 ALA 268 268 268 ALA ALA C . n 
C 1 269 ARG 269 269 269 ARG ARG C . n 
C 1 270 THR 270 270 270 THR THR C . n 
C 1 271 GLU 271 271 271 GLU GLU C . n 
C 1 272 ILE 272 272 272 ILE ILE C . n 
C 1 273 TYR 273 273 273 TYR TYR C . n 
C 1 274 THR 274 274 274 THR THR C . n 
C 1 275 ARG 275 275 275 ARG ARG C . n 
C 1 276 MET 276 276 276 MET MET C . n 
C 1 277 TYR 277 277 277 TYR TYR C . n 
C 1 278 PHE 278 278 278 PHE PHE C . n 
C 1 279 ASN 279 279 279 ASN ASN C . n 
C 1 280 HIS 280 280 280 HIS HIS C . n 
C 1 281 PRO 281 281 281 PRO PRO C . n 
C 1 282 GLY 282 282 282 GLY GLY C . n 
C 1 283 TYR 283 283 283 TYR TYR C . n 
C 1 284 ASP 284 284 284 ASP ASP C . n 
C 1 285 ASP 285 285 285 ASP ASP C . n 
C 1 286 TYR 286 286 286 TYR TYR C . n 
C 1 287 PRO 287 287 287 PRO PRO C . n 
C 1 288 VAL 288 288 288 VAL VAL C . n 
C 1 289 VAL 289 289 289 VAL VAL C . n 
C 1 290 GLY 290 290 290 GLY GLY C . n 
C 1 291 ILE 291 291 291 ILE ILE C . n 
C 1 292 SER 292 292 292 SER SER C . n 
C 1 293 TRP 293 293 293 TRP TRP C . n 
C 1 294 GLU 294 294 294 GLU GLU C . n 
C 1 295 GLN 295 295 295 GLN GLN C . n 
C 1 296 ALA 296 296 296 ALA ALA C . n 
C 1 297 GLN 297 297 297 GLN GLN C . n 
C 1 298 ALA 298 298 298 ALA ALA C . n 
C 1 299 PHE 299 299 299 PHE PHE C . n 
C 1 300 CYS 300 300 300 CYS CYS C . n 
C 1 301 ALA 301 301 301 ALA ALA C . n 
C 1 302 TRP 302 302 302 TRP TRP C . n 
C 1 303 ARG 303 303 303 ARG ARG C . n 
C 1 304 SER 304 304 304 SER SER C . n 
C 1 305 GLU 305 305 305 GLU GLU C . n 
C 1 306 PHE 306 306 306 PHE PHE C . n 
C 1 307 PHE 307 307 307 PHE PHE C . n 
C 1 308 ARG 308 308 308 ARG ARG C . n 
C 1 309 LYS 309 309 309 LYS LYS C . n 
C 1 310 GLY 310 310 310 GLY GLY C . n 
C 1 311 ILE 311 311 311 ILE ILE C . n 
C 1 312 ARG 312 312 312 ARG ARG C . n 
C 1 313 LEU 313 313 313 LEU LEU C . n 
C 1 314 PRO 314 314 314 PRO PRO C . n 
C 1 315 GLU 315 315 315 GLU GLU C . n 
C 1 316 GLY 316 316 316 GLY GLY C . n 
C 1 317 GLN 317 317 317 GLN GLN C . n 
C 1 318 ILE 318 318 318 ILE ILE C . n 
C 1 319 MET 319 319 319 MET MET C . n 
C 1 320 ASP 320 320 320 ASP ASP C . n 
C 1 321 ASP 321 321 321 ASP ASP C . n 
C 1 322 PHE 322 322 322 PHE PHE C . n 
C 1 323 ARG 323 323 323 ARG ARG C . n 
C 1 324 LEU 324 324 324 LEU LEU C . n 
C 1 325 PRO 325 325 325 PRO PRO C . n 
C 1 326 THR 326 326 326 THR THR C . n 
C 1 327 GLU 327 327 327 GLU GLU C . n 
C 1 328 ALA 328 328 328 ALA ALA C . n 
C 1 329 GLU 329 329 329 GLU GLU C . n 
C 1 330 TRP 330 330 330 TRP TRP C . n 
C 1 331 GLU 331 331 331 GLU GLU C . n 
C 1 332 TYR 332 332 332 TYR TYR C . n 
C 1 333 ALA 333 333 333 ALA ALA C . n 
C 1 334 ALA 334 334 334 ALA ALA C . n 
C 1 335 ARG 335 335 335 ARG ARG C . n 
C 1 336 MET 336 336 336 MET MET C . n 
C 1 337 GLY 337 337 337 GLY GLY C . n 
C 1 338 ASP 338 338 338 ASP ASP C . n 
C 1 339 SER 339 339 339 SER SER C . n 
C 1 340 ASN 340 340 340 ASN ASN C . n 
C 1 341 ASN 341 341 341 ASN ASN C . n 
C 1 342 LYS 342 342 342 LYS LYS C . n 
C 1 343 TYR 343 343 343 TYR TYR C . n 
C 1 344 PRO 344 344 344 PRO PRO C . n 
C 1 345 TRP 345 345 345 TRP TRP C . n 
C 1 346 SER 346 346 346 SER SER C . n 
C 1 347 THR 347 347 347 THR THR C . n 
C 1 348 GLU 348 348 348 GLU GLU C . n 
C 1 349 ASP 349 349 349 ASP ASP C . n 
C 1 350 LEU 350 350 350 LEU LEU C . n 
C 1 351 ARG 351 351 351 ARG ARG C . n 
C 1 352 THR 352 352 352 THR THR C . n 
C 1 353 GLY 353 353 353 GLY GLY C . n 
C 1 354 ARG 354 354 354 ARG ARG C . n 
C 1 355 GLY 355 355 355 GLY GLY C . n 
C 1 356 CYS 356 356 356 CYS CYS C . n 
C 1 357 PHE 357 357 357 PHE PHE C . n 
C 1 358 LEU 358 358 358 LEU LEU C . n 
C 1 359 GLY 359 359 359 GLY GLY C . n 
C 1 360 ASN 360 360 360 ASN ASN C . n 
C 1 361 PHE 361 361 361 PHE PHE C . n 
C 1 362 LYS 362 362 362 LYS LYS C . n 
C 1 363 PRO 363 363 363 PRO PRO C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 GLU 365 365 365 GLU GLU C . n 
C 1 366 GLY 366 366 366 GLY GLY C . n 
C 1 367 ASP 367 367 367 ASP ASP C . n 
C 1 368 TYR 368 368 368 TYR TYR C . n 
C 1 369 THR 369 369 369 THR THR C . n 
C 1 370 ALA 370 370 370 ALA ALA C . n 
C 1 371 ASP 371 371 371 ASP ASP C . n 
C 1 372 GLY 372 372 372 GLY GLY C . n 
C 1 373 HIS 373 373 373 HIS HIS C . n 
C 1 374 LEU 374 374 374 LEU LEU C . n 
C 1 375 ILE 375 375 375 ILE ILE C . n 
C 1 376 PRO 376 376 376 PRO PRO C . n 
C 1 377 SER 377 377 377 SER SER C . n 
C 1 378 ARG 378 378 378 ARG ARG C . n 
C 1 379 VAL 379 379 379 VAL VAL C . n 
C 1 380 SER 380 380 380 SER SER C . n 
C 1 381 SER 381 381 381 SER SER C . n 
C 1 382 PHE 382 382 382 PHE PHE C . n 
C 1 383 SER 383 383 383 SER SER C . n 
C 1 384 PRO 384 384 384 PRO PRO C . n 
C 1 385 ASN 385 385 385 ASN ASN C . n 
C 1 386 ASP 386 386 386 ASP ASP C . n 
C 1 387 PHE 387 387 387 PHE PHE C . n 
C 1 388 GLY 388 388 388 GLY GLY C . n 
C 1 389 LEU 389 389 389 LEU LEU C . n 
C 1 390 TYR 390 390 390 TYR TYR C . n 
C 1 391 ASP 391 391 391 ASP ASP C . n 
C 1 392 MET 392 392 392 MET MET C . n 
C 1 393 ALA 393 393 393 ALA ALA C . n 
C 1 394 GLY 394 394 394 GLY GLY C . n 
C 1 395 ASN 395 395 395 ASN ASN C . n 
C 1 396 VAL 396 396 396 VAL VAL C . n 
C 1 397 ALA 397 397 397 ALA ALA C . n 
C 1 398 GLU 398 398 398 GLU GLU C . n 
C 1 399 TRP 399 399 399 TRP TRP C . n 
C 1 400 THR 400 400 400 THR THR C . n 
C 1 401 SER 401 401 401 SER SER C . n 
C 1 402 THR 402 402 402 THR THR C . n 
C 1 403 ALA 403 403 403 ALA ALA C . n 
C 1 404 PHE 404 404 404 PHE PHE C . n 
C 1 405 SER 405 405 405 SER SER C . n 
C 1 406 GLU 406 406 406 GLU GLU C . n 
C 1 407 SER 407 407 407 SER SER C . n 
C 1 408 GLY 408 408 408 GLY GLY C . n 
C 1 409 LEU 409 409 409 LEU LEU C . n 
C 1 410 LYS 410 410 410 LYS LYS C . n 
C 1 411 GLN 411 411 411 GLN GLN C . n 
C 1 412 MET 412 412 412 MET MET C . n 
C 1 413 SER 413 413 413 SER SER C . n 
C 1 414 ASP 414 414 414 ASP ASP C . n 
C 1 415 ILE 415 415 415 ILE ILE C . n 
C 1 416 ASN 416 416 416 ASN ASN C . n 
C 1 417 PRO 417 417 417 PRO PRO C . n 
C 1 418 GLU 418 418 418 GLU GLU C . n 
C 1 419 LEU 419 419 419 LEU LEU C . n 
C 1 420 GLU 420 420 420 GLU GLU C . n 
C 1 421 TYR 421 421 421 TYR TYR C . n 
C 1 422 LYS 422 422 422 LYS LYS C . n 
C 1 423 ALA 423 423 423 ALA ALA C . n 
C 1 424 ALA 424 424 424 ALA ALA C . n 
C 1 425 LEU 425 425 425 LEU LEU C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 ASP 427 427 427 ASP ASP C . n 
C 1 428 PRO 428 428 428 PRO PRO C . n 
C 1 429 TYR 429 429 429 TYR TYR C . n 
C 1 430 ILE 430 430 430 ILE ILE C . n 
C 1 431 LEU 431 431 431 LEU LEU C . n 
C 1 432 LYS 432 432 432 LYS LYS C . n 
C 1 433 GLN 433 433 433 GLN GLN C . n 
C 1 434 LYS 434 434 434 LYS LYS C . n 
C 1 435 VAL 435 435 435 VAL VAL C . n 
C 1 436 VAL 436 436 436 VAL VAL C . n 
C 1 437 ARG 437 437 437 ARG ARG C . n 
C 1 438 GLY 438 438 438 GLY GLY C . n 
C 1 439 GLY 439 439 439 GLY GLY C . n 
C 1 440 SER 440 440 440 SER SER C . n 
C 1 441 TRP 441 441 441 TRP TRP C . n 
C 1 442 LYS 442 442 442 LYS LYS C . n 
C 1 443 ASP 443 443 443 ASP ASP C . n 
C 1 444 VAL 444 444 444 VAL VAL C . n 
C 1 445 ALA 445 445 445 ALA ALA C . n 
C 1 446 ARG 446 446 446 ARG ARG C . n 
C 1 447 PHE 447 447 447 PHE PHE C . n 
C 1 448 ILE 448 448 448 ILE ILE C . n 
C 1 449 ARG 449 449 449 ARG ARG C . n 
C 1 450 SER 450 450 450 SER SER C . n 
C 1 451 ALA 451 451 451 ALA ALA C . n 
C 1 452 THR 452 452 452 THR THR C . n 
C 1 453 ARG 453 453 453 ARG ARG C . n 
C 1 454 SER 454 454 454 SER SER C . n 
C 1 455 HIS 455 455 455 HIS HIS C . n 
C 1 456 GLU 456 456 456 GLU GLU C . n 
C 1 457 TYR 457 457 457 TYR TYR C . n 
C 1 458 GLN 458 458 458 GLN GLN C . n 
C 1 459 ASN 459 459 459 ASN ASN C . n 
C 1 460 VAL 460 460 460 VAL VAL C . n 
C 1 461 GLY 461 461 461 GLY GLY C . n 
C 1 462 ARG 462 462 462 ARG ARG C . n 
C 1 463 SER 463 463 463 SER SER C . n 
C 1 464 TYR 464 464 464 TYR TYR C . n 
C 1 465 ILE 465 465 465 ILE ILE C . n 
C 1 466 GLY 466 466 466 GLY GLY C . n 
C 1 467 PHE 467 467 467 PHE PHE C . n 
C 1 468 ARG 468 468 468 ARG ARG C . n 
C 1 469 CYS 469 469 469 CYS CYS C . n 
C 1 470 VAL 470 470 470 VAL VAL C . n 
C 1 471 ARG 471 471 471 ARG ARG C . n 
C 1 472 THR 472 472 472 THR THR C . n 
C 1 473 SER 473 473 473 SER SER C . n 
C 1 474 ILE 474 474 474 ILE ILE C . n 
C 1 475 ALA 475 475 475 ALA ALA C . n 
C 1 476 PHE 476 476 476 PHE PHE C . n 
C 1 477 SER 477 477 ?   ?   ?   C . n 
C 1 478 SER 478 478 ?   ?   ?   C . n 
C 1 479 GLY 479 479 ?   ?   ?   C . n 
C 1 480 LYS 480 480 ?   ?   ?   C . n 
C 1 481 ALA 481 481 ?   ?   ?   C . n 
C 1 482 PRO 482 482 ?   ?   ?   C . n 
C 1 483 LYS 483 483 ?   ?   ?   C . n 
C 1 484 SER 484 484 ?   ?   ?   C . n 
C 1 485 SER 485 485 ?   ?   ?   C . n 
C 1 486 ARG 486 486 ?   ?   ?   C . n 
C 1 487 ARG 487 487 ?   ?   ?   C . n 
C 1 488 SER 488 488 ?   ?   ?   C . n 
C 1 489 THR 489 489 ?   ?   ?   C . n 
C 1 490 LYS 490 490 ?   ?   ?   C . n 
C 1 491 LYS 491 491 ?   ?   ?   C . n 
D 2 1   MET 1   -1  ?   ?   ?   D . n 
D 2 2   PHE 2   0   ?   ?   ?   D . n 
D 2 3   MET 3   1   ?   ?   ?   D . n 
D 2 4   LYS 4   2   ?   ?   ?   D . n 
D 2 5   VAL 5   3   ?   ?   ?   D . n 
D 2 6   PHE 6   4   ?   ?   ?   D . n 
D 2 7   LYS 7   5   ?   ?   ?   D . n 
D 2 8   ALA 8   6   ?   ?   ?   D . n 
D 2 9   VAL 9   7   ?   ?   ?   D . n 
D 2 10  ILE 10  8   ?   ?   ?   D . n 
D 2 11  GLY 11  9   ?   ?   ?   D . n 
D 2 12  ALA 12  10  ?   ?   ?   D . n 
D 2 13  ILE 13  11  ?   ?   ?   D . n 
D 2 14  LEU 14  12  ?   ?   ?   D . n 
D 2 15  ALA 15  13  ?   ?   ?   D . n 
D 2 16  ALA 16  14  ?   ?   ?   D . n 
D 2 17  THR 17  15  ?   ?   ?   D . n 
D 2 18  VAL 18  16  ?   ?   ?   D . n 
D 2 19  SER 19  17  ?   ?   ?   D . n 
D 2 20  ILE 20  18  ?   ?   ?   D . n 
D 2 21  SER 21  19  ?   ?   ?   D . n 
D 2 22  SER 22  20  ?   ?   ?   D . n 
D 2 23  VAL 23  21  ?   ?   ?   D . n 
D 2 24  ALA 24  22  ?   ?   ?   D . n 
D 2 25  GLN 25  23  ?   ?   ?   D . n 
D 2 26  GLU 26  24  ?   ?   ?   D . n 
D 2 27  ASN 27  25  ?   ?   ?   D . n 
D 2 28  THR 28  26  ?   ?   ?   D . n 
D 2 29  ASN 29  27  ?   ?   ?   D . n 
D 2 30  ASN 30  28  ?   ?   ?   D . n 
D 2 31  ARG 31  29  ?   ?   ?   D . n 
D 2 32  SER 32  30  ?   ?   ?   D . n 
D 2 33  PRO 33  31  ?   ?   ?   D . n 
D 2 34  GLN 34  32  ?   ?   ?   D . n 
D 2 35  VAL 35  33  ?   ?   ?   D . n 
D 2 36  GLY 36  34  ?   ?   ?   D . n 
D 2 37  ARG 37  35  ?   ?   ?   D . n 
D 2 38  ALA 38  36  ?   ?   ?   D . n 
D 2 39  PRO 39  37  ?   ?   ?   D . n 
D 2 40  ARG 40  38  ?   ?   ?   D . n 
D 2 41  ASN 41  39  ?   ?   ?   D . n 
D 2 42  THR 42  40  ?   ?   ?   D . n 
D 2 43  GLU 43  41  ?   ?   ?   D . n 
D 2 44  VAL 44  42  ?   ?   ?   D . n 
D 2 45  GLU 45  43  ?   ?   ?   D . n 
D 2 46  GLN 46  44  ?   ?   ?   D . n 
D 2 47  THR 47  45  ?   ?   ?   D . n 
D 2 48  THR 48  46  ?   ?   ?   D . n 
D 2 49  THR 49  47  47  THR THR D . n 
D 2 50  LEU 50  48  48  LEU LEU D . n 
D 2 51  SER 51  49  49  SER SER D . n 
D 2 52  ASN 52  50  50  ASN ASN D . n 
D 2 53  ARG 53  51  51  ARG ARG D . n 
D 2 54  ALA 54  52  52  ALA ALA D . n 
D 2 55  GLN 55  53  53  GLN GLN D . n 
D 2 56  GLU 56  54  54  GLU GLU D . n 
D 2 57  PHE 57  55  55  PHE PHE D . n 
D 2 58  ASN 58  56  56  ASN ASN D . n 
D 2 59  ARG 59  57  57  ARG ARG D . n 
D 2 60  ARG 60  58  58  ARG ARG D . n 
D 2 61  LEU 61  59  59  LEU LEU D . n 
D 2 62  THR 62  60  60  THR THR D . n 
D 2 63  GLN 63  61  61  GLN GLN D . n 
D 2 64  LYS 64  62  62  LYS LYS D . n 
D 2 65  THR 65  63  63  THR THR D . n 
D 2 66  ASP 66  64  64  ASP ASP D . n 
D 2 67  ASN 67  65  65  ASN ASN D . n 
D 2 68  ALA 68  66  66  ALA ALA D . n 
D 2 69  PRO 69  67  67  PRO PRO D . n 
D 2 70  TRP 70  68  68  TRP TRP D . n 
D 2 71  ARG 71  69  69  ARG ARG D . n 
D 2 72  ARG 72  70  70  ARG ARG D . n 
D 2 73  VAL 73  71  71  VAL VAL D . n 
D 2 74  VAL 74  72  72  VAL VAL D . n 
D 2 75  TYR 75  73  73  TYR TYR D . n 
D 2 76  ARG 76  74  74  ARG ARG D . n 
D 2 77  ARG 77  75  75  ARG ARG D . n 
D 2 78  VAL 78  76  76  VAL VAL D . n 
D 2 79  ASP 79  77  77  ASP ASP D . n 
D 2 80  LEU 80  78  78  LEU LEU D . n 
D 2 81  MET 81  79  79  MET MET D . n 
D 2 82  GLU 82  80  80  GLU GLU D . n 
D 2 83  GLU 83  81  81  GLU GLU D . n 
D 2 84  SER 84  82  82  SER SER D . n 
D 2 85  ASN 85  83  83  ASN ASN D . n 
D 2 86  ALA 86  84  84  ALA ALA D . n 
D 2 87  VAL 87  85  85  VAL VAL D . n 
D 2 88  LEU 88  86  86  LEU LEU D . n 
D 2 89  TYR 89  87  87  TYR TYR D . n 
D 2 90  TYR 90  88  88  TYR TYR D . n 
D 2 91  PRO 91  89  89  PRO PRO D . n 
D 2 92  PRO 92  90  90  PRO PRO D . n 
D 2 93  ARG 93  91  91  ARG ARG D . n 
D 2 94  PRO 94  92  92  PRO PRO D . n 
D 2 95  ILE 95  93  93  ILE ILE D . n 
D 2 96  GLY 96  94  94  GLY GLY D . n 
D 2 97  ASP 97  95  95  ASP ASP D . n 
D 2 98  ARG 98  96  96  ARG ARG D . n 
D 2 99  LYS 99  97  97  LYS LYS D . n 
D 2 100 ASN 100 98  98  ASN ASN D . n 
D 2 101 LEU 101 99  99  LEU LEU D . n 
D 2 102 PHE 102 100 100 PHE PHE D . n 
D 2 103 SER 103 101 101 SER SER D . n 
D 2 104 THR 104 102 102 THR THR D . n 
D 2 105 ILE 105 103 103 ILE ILE D . n 
D 2 106 PHE 106 104 104 PHE PHE D . n 
D 2 107 GLY 107 105 105 GLY GLY D . n 
D 2 108 LEU 108 106 106 LEU LEU D . n 
D 2 109 ILE 109 107 107 ILE ILE D . n 
D 2 110 ASN 110 108 108 ASN ASN D . n 
D 2 111 SER 111 109 109 SER SER D . n 
D 2 112 ASN 112 110 110 ASN ASN D . n 
D 2 113 SER 113 111 111 SER SER D . n 
D 2 114 LEU 114 112 112 LEU LEU D . n 
D 2 115 ASP 115 113 113 ASP ASP D . n 
D 2 116 VAL 116 114 114 VAL VAL D . n 
D 2 117 TYR 117 115 115 TYR TYR D . n 
D 2 118 GLU 118 116 116 GLU GLU D . n 
D 2 119 TYR 119 117 117 TYR TYR D . n 
D 2 120 LEU 120 118 118 LEU LEU D . n 
D 2 121 ASP 121 119 119 ASP ASP D . n 
D 2 122 GLY 122 120 120 GLY GLY D . n 
D 2 123 PHE 123 121 121 PHE PHE D . n 
D 2 124 GLU 124 122 122 GLU GLU D . n 
D 2 125 ALA 125 123 123 ALA ALA D . n 
D 2 126 PHE 126 124 124 PHE PHE D . n 
D 2 127 THR 127 125 125 THR THR D . n 
D 2 128 ASP 128 126 126 ASP ASP D . n 
D 2 129 GLN 129 127 127 GLN GLN D . n 
D 2 130 TYR 130 128 128 TYR TYR D . n 
D 2 131 LYS 131 129 129 LYS LYS D . n 
D 2 132 ILE 132 130 130 ILE ILE D . n 
D 2 133 LYS 133 131 131 LYS LYS D . n 
D 2 134 PHE 134 132 132 PHE PHE D . n 
D 2 135 GLN 135 133 133 GLN GLN D . n 
D 2 136 GLU 136 134 134 GLU GLU D . n 
D 2 137 PHE 137 135 135 PHE PHE D . n 
D 2 138 LEU 138 136 136 LEU LEU D . n 
D 2 139 ASP 139 137 137 ASP ASP D . n 
D 2 140 ARG 140 138 138 ARG ARG D . n 
D 2 141 PHE 141 139 139 PHE PHE D . n 
D 2 142 GLY 142 140 140 GLY GLY D . n 
D 2 143 ILE 143 141 141 ILE ILE D . n 
D 2 144 TYR 144 142 142 TYR TYR D . n 
D 2 145 TYR 145 143 143 TYR TYR D . n 
D 2 146 GLN 146 144 144 GLN GLN D . n 
D 2 147 PRO 147 145 145 PRO PRO D . n 
D 2 148 SER 148 146 146 SER SER D . n 
D 2 149 THR 149 147 147 THR THR D . n 
D 2 150 ASN 150 148 148 ASN ASN D . n 
D 2 151 LYS 151 149 149 LYS LYS D . n 
D 2 152 ASN 152 150 150 ASN ASN D . n 
D 2 153 ALA 153 151 151 ALA ALA D . n 
D 2 154 GLU 154 152 152 GLU GLU D . n 
D 2 155 LEU 155 153 153 LEU LEU D . n 
D 2 156 PHE 156 154 154 PHE PHE D . n 
D 2 157 LYS 157 155 155 LYS LYS D . n 
D 2 158 VAL 158 156 156 VAL VAL D . n 
D 2 159 ALA 159 157 157 ALA ALA D . n 
D 2 160 ASP 160 158 158 ASP ASP D . n 
D 2 161 SER 161 159 159 SER SER D . n 
D 2 162 ASP 162 160 160 ASP ASP D . n 
D 2 163 ILE 163 161 161 ILE ILE D . n 
D 2 164 PRO 164 162 162 PRO PRO D . n 
D 2 165 SER 165 163 163 SER SER D . n 
D 2 166 ALA 166 164 164 ALA ALA D . n 
D 2 167 GLU 167 165 165 GLU GLU D . n 
D 2 168 VAL 168 166 166 VAL VAL D . n 
D 2 169 LYS 169 167 167 LYS LYS D . n 
D 2 170 ALA 170 168 168 ALA ALA D . n 
D 2 171 TYR 171 169 169 TYR TYR D . n 
D 2 172 TYR 172 170 170 TYR TYR D . n 
D 2 173 VAL 173 171 171 VAL VAL D . n 
D 2 174 LYS 174 172 172 LYS LYS D . n 
D 2 175 GLU 175 173 173 GLU GLU D . n 
D 2 176 GLU 176 174 174 GLU GLU D . n 
D 2 177 TRP 177 175 175 TRP TRP D . n 
D 2 178 TYR 178 176 176 TYR TYR D . n 
D 2 179 PHE 179 177 177 PHE PHE D . n 
D 2 180 THR 180 178 178 THR THR D . n 
D 2 181 PRO 181 179 179 PRO PRO D . n 
D 2 182 THR 182 180 180 THR THR D . n 
D 2 183 ASN 183 181 181 ASN ASN D . n 
D 2 184 SER 184 182 182 SER SER D . n 
D 2 185 ASP 185 183 183 ASP ASP D . n 
D 2 186 VAL 186 184 184 VAL VAL D . n 
D 2 187 ASP 187 185 185 ASP ASP D . n 
D 2 188 ILE 188 186 186 ILE ILE D . n 
D 2 189 LYS 189 187 187 LYS LYS D . n 
D 2 190 ILE 190 188 188 ILE ILE D . n 
D 2 191 GLN 191 189 189 GLN GLN D . n 
D 2 192 ALA 192 190 190 ALA ALA D . n 
D 2 193 ILE 193 191 191 ILE ILE D . n 
D 2 194 CYS 194 192 192 CYS CYS D . n 
D 2 195 PRO 195 193 193 PRO PRO D . n 
D 2 196 ILE 196 194 194 ILE ILE D . n 
D 2 197 MET 197 195 195 MET MET D . n 
D 2 198 THR 198 196 196 THR THR D . n 
D 2 199 GLY 199 197 197 GLY GLY D . n 
D 2 200 GLN 200 198 198 GLN GLN D . n 
D 2 201 ASP 201 199 199 ASP ASP D . n 
D 2 202 GLU 202 200 200 GLU GLU D . n 
D 2 203 PHE 203 201 201 PHE PHE D . n 
D 2 204 GLY 204 202 202 GLY GLY D . n 
D 2 205 GLU 205 203 203 GLU GLU D . n 
D 2 206 VAL 206 204 204 VAL VAL D . n 
D 2 207 ARG 207 205 205 ARG ARG D . n 
D 2 208 ASN 208 206 206 ASN ASN D . n 
D 2 209 GLN 209 207 207 GLN GLN D . n 
D 2 210 PRO 210 208 208 PRO PRO D . n 
D 2 211 LEU 211 209 209 LEU LEU D . n 
D 2 212 PHE 212 210 210 PHE PHE D . n 
D 2 213 TRP 213 211 211 TRP TRP D . n 
D 2 214 ILE 214 212 212 ILE ILE D . n 
D 2 215 PRO 215 213 213 PRO PRO D . n 
D 2 216 TYR 216 214 214 TYR TYR D . n 
D 2 217 GLU 217 215 215 GLU GLU D . n 
D 2 218 ASN 218 216 216 ASN ASN D . n 
D 2 219 ILE 219 217 217 ILE ILE D . n 
D 2 220 ARG 220 218 218 ARG ARG D . n 
D 2 221 PRO 221 219 219 PRO PRO D . n 
D 2 222 TYR 222 220 220 TYR TYR D . n 
D 2 223 ILE 223 221 221 ILE ILE D . n 
D 2 224 ALA 224 222 222 ALA ALA D . n 
D 2 225 ARG 225 223 223 ARG ARG D . n 
D 2 226 GLU 226 224 224 GLU GLU D . n 
D 2 227 ARG 227 225 225 ARG ARG D . n 
D 2 228 VAL 228 226 226 VAL VAL D . n 
D 2 229 MET 229 227 227 MET MET D . n 
D 2 230 LEU 230 228 228 LEU LEU D . n 
D 2 231 SER 231 229 229 SER SER D . n 
D 2 232 SER 232 230 230 SER SER D . n 
D 2 233 LEU 233 231 231 LEU LEU D . n 
D 2 234 ASN 234 232 232 ASN ASN D . n 
D 2 235 ASN 235 233 233 ASN ASN D . n 
D 2 236 THR 236 234 234 THR THR D . n 
D 2 237 ARG 237 235 235 ARG ARG D . n 
D 2 238 ASN 238 236 236 ASN ASN D . n 
D 2 239 SER 239 237 237 SER SER D . n 
D 2 240 THR 240 238 238 THR THR D . n 
D 2 241 ILE 241 239 239 ILE ILE D . n 
D 2 242 ASP 242 240 240 ASP ASP D . n 
D 2 243 ASP 243 241 241 ASP ASP D . n 
D 2 244 PHE 244 242 242 PHE PHE D . n 
D 2 245 PHE 245 243 243 PHE PHE D . n 
D 2 246 ARG 246 244 244 ARG ARG D . n 
D 2 247 LEU 247 245 245 LEU LEU D . n 
D 2 248 ASN 248 246 246 ASN ASN D . n 
D 2 249 LEU 249 247 247 LEU LEU D . n 
D 2 250 TYR 250 248 248 TYR TYR D . n 
D 2 251 LYS 251 249 249 LYS LYS D . n 
D 2 252 GLY 252 250 250 GLY GLY D . n 
D 2 253 ASP 253 251 251 ASP ASP D . n 
D 2 254 ILE 254 252 252 ILE ILE D . n 
D 2 255 VAL 255 253 253 VAL VAL D . n 
D 2 256 LYS 256 254 254 LYS LYS D . n 
D 2 257 THR 257 255 255 THR THR D . n 
D 2 258 GLU 258 256 256 GLU GLU D . n 
D 2 259 ASN 259 257 257 ASN ASN D . n 
D 2 260 LEU 260 258 258 LEU LEU D . n 
D 2 261 HIS 261 259 259 HIS HIS D . n 
D 2 262 ASN 262 260 260 ASN ASN D . n 
D 2 263 ARG 263 261 261 ARG ARG D . n 
D 2 264 ALA 264 262 262 ALA ALA D . n 
D 2 265 LEU 265 263 263 LEU LEU D . n 
D 2 266 ALA 266 264 264 ALA ALA D . n 
D 2 267 GLU 267 265 265 GLU GLU D . n 
D 2 268 TYR 268 266 266 TYR TYR D . n 
D 2 269 CYS 269 267 267 CYS CYS D . n 
D 2 270 PRO 270 268 268 PRO PRO D . n 
D 2 271 THR 271 269 269 THR THR D . n 
D 2 272 PRO 272 270 270 PRO PRO D . n 
D 2 273 ASP 273 271 271 ASP ASP D . n 
D 2 274 SER 274 272 272 SER SER D . n 
D 2 275 MET 275 273 273 MET MET D . n 
D 2 276 LYS 276 274 274 LYS LYS D . n 
D 2 277 MET 277 275 275 MET MET D . n 
D 2 278 GLU 278 276 276 GLU GLU D . n 
D 2 279 SER 279 277 277 SER SER D . n 
D 2 280 LYS 280 278 278 LYS LYS D . n 
D 2 281 ARG 281 279 279 ARG ARG D . n 
D 2 282 ILE 282 280 280 ILE ILE D . n 
D 2 283 ASP 283 281 281 ASP ASP D . n 
D 2 284 LYS 284 282 282 LYS LYS D . n 
D 2 285 GLU 285 283 283 GLU GLU D . n 
D 2 286 LEU 286 284 284 LEU LEU D . n 
D 2 287 GLN 287 285 285 GLN GLN D . n 
D 2 288 GLY 288 286 286 GLY GLY D . n 
D 2 289 PHE 289 287 287 PHE PHE D . n 
D 2 290 ARG 290 288 288 ARG ARG D . n 
D 2 291 ASP 291 289 289 ASP ASP D . n 
D 2 292 GLY 292 290 290 GLY GLY D . n 
D 2 293 LEU 293 291 291 LEU LEU D . n 
D 2 294 PHE 294 292 292 PHE PHE D . n 
D 2 295 VAL 295 293 293 VAL VAL D . n 
D 2 296 THR 296 294 294 THR THR D . n 
D 2 297 GLN 297 295 295 GLN GLN D . n 
D 2 298 ASP 298 296 296 ASP ASP D . n 
D 2 299 THR 299 297 297 THR THR D . n 
D 2 300 THR 300 298 298 THR THR D . n 
D 2 301 TRP 301 299 299 TRP TRP D . n 
D 2 302 MET 302 300 ?   ?   ?   D . n 
D 2 303 LYS 303 301 ?   ?   ?   D . n 
D 2 304 GLN 304 302 ?   ?   ?   D . n 
D 2 305 ALA 305 303 ?   ?   ?   D . n 
D 2 306 GLU 306 304 ?   ?   ?   D . n 
D 2 307 THR 307 305 ?   ?   ?   D . n 
D 2 308 LYS 308 306 ?   ?   ?   D . n 
D 2 309 LYS 309 307 ?   ?   ?   D . n 
D 2 310 SER 310 308 ?   ?   ?   D . n 
D 2 311 LYS 311 309 ?   ?   ?   D . n 
D 2 312 GLY 312 310 ?   ?   ?   D . n 
D 2 313 LYS 313 311 ?   ?   ?   D . n 
D 2 314 LYS 314 312 ?   ?   ?   D . n 
D 2 315 LEU 315 313 ?   ?   ?   D . n 
D 2 316 GLU 316 314 ?   ?   ?   D . n 
D 2 317 LYS 317 315 ?   ?   ?   D . n 
D 2 318 ALA 318 316 ?   ?   ?   D . n 
D 2 319 ARG 319 317 ?   ?   ?   D . n 
D 2 320 GLY 320 318 ?   ?   ?   D . n 
D 2 321 LYS 321 319 ?   ?   ?   D . n 
D 2 322 ASN 322 320 ?   ?   ?   D . n 
D 2 323 ILE 323 321 ?   ?   ?   D . n 
D 2 324 THR 324 322 ?   ?   ?   D . n 
D 2 325 SER 325 323 ?   ?   ?   D . n 
D 2 326 ARG 326 324 ?   ?   ?   D . n 
D 2 327 THR 327 325 ?   ?   ?   D . n 
D 2 328 ARG 328 326 ?   ?   ?   D . n 
D 2 329 GLY 329 327 ?   ?   ?   D . n 
D 2 330 GLN 330 328 ?   ?   ?   D . n 
D 2 331 GLY 331 329 ?   ?   ?   D . n 
D 2 332 GLU 332 330 ?   ?   ?   D . n 
D 2 333 GLY 333 331 ?   ?   ?   D . n 
D 2 334 ALA 334 332 ?   ?   ?   D . n 
D 2 335 ALA 335 333 ?   ?   ?   D . n 
D 2 336 GLU 336 334 ?   ?   ?   D . n 
D 2 337 THR 337 335 ?   ?   ?   D . n 
D 2 338 GLU 338 336 ?   ?   ?   D . n 
D 2 339 ALA 339 337 ?   ?   ?   D . n 
D 2 340 VAL 340 338 ?   ?   ?   D . n 
D 2 341 GLU 341 339 ?   ?   ?   D . n 
D 2 342 PRO 342 340 ?   ?   ?   D . n 
D 2 343 LYS 343 341 ?   ?   ?   D . n 
D 2 344 LYS 344 342 ?   ?   ?   D . n 
D 2 345 GLN 345 343 ?   ?   ?   D . n 
D 2 346 LYS 346 344 ?   ?   ?   D . n 
D 2 347 ALA 347 345 ?   ?   ?   D . n 
D 2 348 SER 348 346 ?   ?   ?   D . n 
D 2 349 LYS 349 347 ?   ?   ?   D . n 
D 2 350 ASN 350 348 ?   ?   ?   D . n 
D 2 351 LYS 351 349 ?   ?   ?   D . n 
D 2 352 ALA 352 350 ?   ?   ?   D . n 
D 2 353 ALA 353 351 ?   ?   ?   D . n 
D 2 354 THR 354 352 ?   ?   ?   D . n 
D 2 355 ARG 355 353 ?   ?   ?   D . n 
D 2 356 SER 356 354 ?   ?   ?   D . n 
D 2 357 VAL 357 355 ?   ?   ?   D . n 
D 2 358 ARG 358 356 ?   ?   ?   D . n 
D 2 359 ARG 359 357 ?   ?   ?   D . n 
D 2 360 ARG 360 358 ?   ?   ?   D . n 
D 2 361 LYS 361 359 ?   ?   ?   D . n 
E 1 1   MET 1   1   ?   ?   ?   E . n 
E 1 2   CYS 2   2   ?   ?   ?   E . n 
E 1 3   ARG 3   3   ?   ?   ?   E . n 
E 1 4   LYS 4   4   ?   ?   ?   E . n 
E 1 5   ASN 5   5   ?   ?   ?   E . n 
E 1 6   ARG 6   6   ?   ?   ?   E . n 
E 1 7   PHE 7   7   ?   ?   ?   E . n 
E 1 8   PHE 8   8   ?   ?   ?   E . n 
E 1 9   ALA 9   9   ?   ?   ?   E . n 
E 1 10  LEU 10  10  ?   ?   ?   E . n 
E 1 11  ALA 11  11  ?   ?   ?   E . n 
E 1 12  GLY 12  12  ?   ?   ?   E . n 
E 1 13  PHE 13  13  ?   ?   ?   E . n 
E 1 14  PHE 14  14  ?   ?   ?   E . n 
E 1 15  LEU 15  15  ?   ?   ?   E . n 
E 1 16  PHE 16  16  ?   ?   ?   E . n 
E 1 17  GLY 17  17  ?   ?   ?   E . n 
E 1 18  VAL 18  18  ?   ?   ?   E . n 
E 1 19  PHE 19  19  ?   ?   ?   E . n 
E 1 20  THR 20  20  ?   ?   ?   E . n 
E 1 21  ILE 21  21  ?   ?   ?   E . n 
E 1 22  SER 22  22  ?   ?   ?   E . n 
E 1 23  SER 23  23  ?   ?   ?   E . n 
E 1 24  CYS 24  24  ?   ?   ?   E . n 
E 1 25  GLY 25  25  ?   ?   ?   E . n 
E 1 26  SER 26  26  ?   ?   ?   E . n 
E 1 27  SER 27  27  ?   ?   ?   E . n 
E 1 28  LYS 28  28  ?   ?   ?   E . n 
E 1 29  ARG 29  29  ?   ?   ?   E . n 
E 1 30  ALA 30  30  ?   ?   ?   E . n 
E 1 31  VAL 31  31  ?   ?   ?   E . n 
E 1 32  GLY 32  32  32  GLY GLY E . n 
E 1 33  GLY 33  33  33  GLY GLY E . n 
E 1 34  GLU 34  34  34  GLU GLU E . n 
E 1 35  LEU 35  35  35  LEU LEU E . n 
E 1 36  THR 36  36  36  THR THR E . n 
E 1 37  GLY 37  37  37  GLY GLY E . n 
E 1 38  ALA 38  38  38  ALA ALA E . n 
E 1 39  LYS 39  39  39  LYS LYS E . n 
E 1 40  LEU 40  40  40  LEU LEU E . n 
E 1 41  SER 41  41  41  SER SER E . n 
E 1 42  SER 42  42  42  SER SER E . n 
E 1 43  TRP 43  43  43  TRP TRP E . n 
E 1 44  ASN 44  44  44  ASN ASN E . n 
E 1 45  GLU 45  45  45  GLU GLU E . n 
E 1 46  PRO 46  46  46  PRO PRO E . n 
E 1 47  SER 47  47  47  SER SER E . n 
E 1 48  PRO 48  48  48  PRO PRO E . n 
E 1 49  PHE 49  49  49  PHE PHE E . n 
E 1 50  GLY 50  50  50  GLY GLY E . n 
E 1 51  MET 51  51  51  MET MET E . n 
E 1 52  ILE 52  52  52  ILE ILE E . n 
E 1 53  GLN 53  53  53  GLN GLN E . n 
E 1 54  VAL 54  54  54  VAL VAL E . n 
E 1 55  PRO 55  55  55  PRO PRO E . n 
E 1 56  ARG 56  56  56  ARG ARG E . n 
E 1 57  GLY 57  57  57  GLY GLY E . n 
E 1 58  SER 58  58  58  SER SER E . n 
E 1 59  ILE 59  59  59  ILE ILE E . n 
E 1 60  VAL 60  60  60  VAL VAL E . n 
E 1 61  LEU 61  61  61  LEU LEU E . n 
E 1 62  GLY 62  62  62  GLY GLY E . n 
E 1 63  ASN 63  63  63  ASN ASN E . n 
E 1 64  LYS 64  64  64  LYS LYS E . n 
E 1 65  GLU 65  65  65  GLU GLU E . n 
E 1 66  ALA 66  66  66  ALA ALA E . n 
E 1 67  ASP 67  67  67  ASP ASP E . n 
E 1 68  SER 68  68  68  SER SER E . n 
E 1 69  LEU 69  69  69  LEU LEU E . n 
E 1 70  TRP 70  70  70  TRP TRP E . n 
E 1 71  GLY 71  71  71  GLY GLY E . n 
E 1 72  ILE 72  72  72  ILE ILE E . n 
E 1 73  PRO 73  73  73  PRO PRO E . n 
E 1 74  ALA 74  74  74  ALA ALA E . n 
E 1 75  GLU 75  75  75  GLU GLU E . n 
E 1 76  SER 76  76  76  SER SER E . n 
E 1 77  ARG 77  77  77  ARG ARG E . n 
E 1 78  PRO 78  78  78  PRO PRO E . n 
E 1 79  ILE 79  79  79  ILE ILE E . n 
E 1 80  SER 80  80  80  SER SER E . n 
E 1 81  VAL 81  81  81  VAL VAL E . n 
E 1 82  ASP 82  82  82  ASP ASP E . n 
E 1 83  ALA 83  83  83  ALA ALA E . n 
E 1 84  PHE 84  84  84  PHE PHE E . n 
E 1 85  TRP 85  85  85  TRP TRP E . n 
E 1 86  MET 86  86  86  MET MET E . n 
E 1 87  ASP 87  87  87  ASP ASP E . n 
E 1 88  ARG 88  88  88  ARG ARG E . n 
E 1 89  THR 89  89  89  THR THR E . n 
E 1 90  GLU 90  90  90  GLU GLU E . n 
E 1 91  ILE 91  91  91  ILE ILE E . n 
E 1 92  THR 92  92  92  THR THR E . n 
E 1 93  ASN 93  93  93  ASN ASN E . n 
E 1 94  ALA 94  94  94  ALA ALA E . n 
E 1 95  GLN 95  95  95  GLN GLN E . n 
E 1 96  TYR 96  96  96  TYR TYR E . n 
E 1 97  ARG 97  97  97  ARG ARG E . n 
E 1 98  GLN 98  98  98  GLN GLN E . n 
E 1 99  PHE 99  99  99  PHE PHE E . n 
E 1 100 VAL 100 100 100 VAL VAL E . n 
E 1 101 TYR 101 101 101 TYR TYR E . n 
E 1 102 TYR 102 102 102 TYR TYR E . n 
E 1 103 VAL 103 103 103 VAL VAL E . n 
E 1 104 ARG 104 104 104 ARG ARG E . n 
E 1 105 ASP 105 105 105 ASP ASP E . n 
E 1 106 SER 106 106 106 SER SER E . n 
E 1 107 ILE 107 107 107 ILE ILE E . n 
E 1 108 ILE 108 108 108 ILE ILE E . n 
E 1 109 ARG 109 109 109 ARG ARG E . n 
E 1 110 GLU 110 110 110 GLU GLU E . n 
E 1 111 ARG 111 111 111 ARG ARG E . n 
E 1 112 LEU 112 112 112 LEU LEU E . n 
E 1 113 ALA 113 113 113 ALA ALA E . n 
E 1 114 ASP 114 114 114 ASP ASP E . n 
E 1 115 PRO 115 115 115 PRO PRO E . n 
E 1 116 ALA 116 116 116 ALA ALA E . n 
E 1 117 TYR 117 117 117 TYR TYR E . n 
E 1 118 GLY 118 118 118 GLY GLY E . n 
E 1 119 GLY 119 119 119 GLY GLY E . n 
E 1 120 ASN 120 120 120 ASN ASN E . n 
E 1 121 GLU 121 121 121 GLU GLU E . n 
E 1 122 GLU 122 122 122 GLU GLU E . n 
E 1 123 TYR 123 123 123 TYR TYR E . n 
E 1 124 LYS 124 124 124 LYS LYS E . n 
E 1 125 ILE 125 125 125 ILE ILE E . n 
E 1 126 THR 126 126 126 THR THR E . n 
E 1 127 GLU 127 127 127 GLU GLU E . n 
E 1 128 ASN 128 128 128 ASN ASN E . n 
E 1 129 LYS 129 129 129 LYS LYS E . n 
E 1 130 PHE 130 130 130 PHE PHE E . n 
E 1 131 GLY 131 131 131 GLY GLY E . n 
E 1 132 GLU 132 132 132 GLU GLU E . n 
E 1 133 PRO 133 133 133 PRO PRO E . n 
E 1 134 VAL 134 134 134 VAL VAL E . n 
E 1 135 THR 135 135 135 THR THR E . n 
E 1 136 PRO 136 136 136 PRO PRO E . n 
E 1 137 HIS 137 137 137 HIS HIS E . n 
E 1 138 LEU 138 138 138 LEU LEU E . n 
E 1 139 ASP 139 139 139 ASP ASP E . n 
E 1 140 TRP 140 140 140 TRP TRP E . n 
E 1 141 SER 141 141 141 SER SER E . n 
E 1 142 LYS 142 142 142 LYS LYS E . n 
E 1 143 PRO 143 143 143 PRO PRO E . n 
E 1 144 ILE 144 144 144 ILE ILE E . n 
E 1 145 PRO 145 145 145 PRO PRO E . n 
E 1 146 SER 146 146 146 SER SER E . n 
E 1 147 GLU 147 147 147 GLU GLU E . n 
E 1 148 LYS 148 148 148 LYS LYS E . n 
E 1 149 ARG 149 149 149 ARG ARG E . n 
E 1 150 ALA 150 150 150 ALA ALA E . n 
E 1 151 THR 151 151 151 THR THR E . n 
E 1 152 GLU 152 152 152 GLU GLU E . n 
E 1 153 GLU 153 153 153 GLU GLU E . n 
E 1 154 GLU 154 154 154 GLU GLU E . n 
E 1 155 ILE 155 155 155 ILE ILE E . n 
E 1 156 ALA 156 156 156 ALA ALA E . n 
E 1 157 ALA 157 157 157 ALA ALA E . n 
E 1 158 ILE 158 158 158 ILE ILE E . n 
E 1 159 ASN 159 159 159 ASN ASN E . n 
E 1 160 SER 160 160 160 SER SER E . n 
E 1 161 VAL 161 161 161 VAL VAL E . n 
E 1 162 TYR 162 162 162 TYR TYR E . n 
E 1 163 TYR 163 163 163 TYR TYR E . n 
E 1 164 THR 164 164 164 THR THR E . n 
E 1 165 ASN 165 165 165 ASN ASN E . n 
E 1 166 PRO 166 166 166 PRO PRO E . n 
E 1 167 VAL 167 167 167 VAL VAL E . n 
E 1 168 THR 168 168 168 THR THR E . n 
E 1 169 HIS 169 169 169 HIS HIS E . n 
E 1 170 ASP 170 170 170 ASP ASP E . n 
E 1 171 ARG 171 171 171 ARG ARG E . n 
E 1 172 LYS 172 172 172 LYS LYS E . n 
E 1 173 LEU 173 173 173 LEU LEU E . n 
E 1 174 ASN 174 174 174 ASN ASN E . n 
E 1 175 PRO 175 175 175 PRO PRO E . n 
E 1 176 ASP 176 176 176 ASP ASP E . n 
E 1 177 GLN 177 177 177 GLN GLN E . n 
E 1 178 MET 178 178 178 MET MET E . n 
E 1 179 VAL 179 179 179 VAL VAL E . n 
E 1 180 TYR 180 180 180 TYR TYR E . n 
E 1 181 ARG 181 181 181 ARG ARG E . n 
E 1 182 TYR 182 182 182 TYR TYR E . n 
E 1 183 GLU 183 183 183 GLU GLU E . n 
E 1 184 VAL 184 184 184 VAL VAL E . n 
E 1 185 TYR 185 185 185 TYR TYR E . n 
E 1 186 ASP 186 186 186 ASP ASP E . n 
E 1 187 TYR 187 187 187 TYR TYR E . n 
E 1 188 ARG 188 188 188 ARG ARG E . n 
E 1 189 SER 189 189 189 SER SER E . n 
E 1 190 ALA 190 190 190 ALA ALA E . n 
E 1 191 ALA 191 191 191 ALA ALA E . n 
E 1 192 LEU 192 192 192 LEU LEU E . n 
E 1 193 ARG 193 193 193 ARG ARG E . n 
E 1 194 GLU 194 194 194 GLU GLU E . n 
E 1 195 HIS 195 195 195 HIS HIS E . n 
E 1 196 GLN 196 196 196 GLN GLN E . n 
E 1 197 LEU 197 197 197 LEU LEU E . n 
E 1 198 LYS 198 198 198 LYS LYS E . n 
E 1 199 ALA 199 199 199 ALA ALA E . n 
E 1 200 ALA 200 200 200 ALA ALA E . n 
E 1 201 LYS 201 201 201 LYS LYS E . n 
E 1 202 ARG 202 202 202 ARG ARG E . n 
E 1 203 ASN 203 203 203 ASN ASN E . n 
E 1 204 LEU 204 204 204 LEU LEU E . n 
E 1 205 ASN 205 205 205 ASN ASN E . n 
E 1 206 THR 206 206 206 THR THR E . n 
E 1 207 ASP 207 207 207 ASP ASP E . n 
E 1 208 ILE 208 208 208 ILE ILE E . n 
E 1 209 LYS 209 209 209 LYS LYS E . n 
E 1 210 VAL 210 210 210 VAL VAL E . n 
E 1 211 ASP 211 211 211 ASP ASP E . n 
E 1 212 PRO 212 212 212 PRO PRO E . n 
E 1 213 ASN 213 213 213 ASN ASN E . n 
E 1 214 ALA 214 214 214 ALA ALA E . n 
E 1 215 VAL 215 215 215 VAL VAL E . n 
E 1 216 VAL 216 216 216 VAL VAL E . n 
E 1 217 MET 217 217 217 MET MET E . n 
E 1 218 ILE 218 218 218 ILE ILE E . n 
E 1 219 SER 219 219 219 SER SER E . n 
E 1 220 LYS 220 220 220 LYS LYS E . n 
E 1 221 ASP 221 221 221 ASP ASP E . n 
E 1 222 THR 222 222 222 THR THR E . n 
E 1 223 ALA 223 223 223 ALA ALA E . n 
E 1 224 PHE 224 224 224 PHE PHE E . n 
E 1 225 VAL 225 225 225 VAL VAL E . n 
E 1 226 ASP 226 226 226 ASP ASP E . n 
E 1 227 GLU 227 227 227 GLU GLU E . n 
E 1 228 SER 228 228 228 SER SER E . n 
E 1 229 GLY 229 229 229 GLY GLY E . n 
E 1 230 ASN 230 230 230 ASN ASN E . n 
E 1 231 ILE 231 231 231 ILE ILE E . n 
E 1 232 ILE 232 232 232 ILE ILE E . n 
E 1 233 SER 233 233 233 SER SER E . n 
E 1 234 GLU 234 234 234 GLU GLU E . n 
E 1 235 THR 235 235 235 THR THR E . n 
E 1 236 ILE 236 236 236 ILE ILE E . n 
E 1 237 THR 237 237 237 THR THR E . n 
E 1 238 ARG 238 238 238 ARG ARG E . n 
E 1 239 PRO 239 239 239 PRO PRO E . n 
E 1 240 LEU 240 240 240 LEU LEU E . n 
E 1 241 SER 241 241 241 SER SER E . n 
E 1 242 SER 242 242 242 SER SER E . n 
E 1 243 GLU 243 243 243 GLU GLU E . n 
E 1 244 TYR 244 244 244 TYR TYR E . n 
E 1 245 ASP 245 245 245 ASP ASP E . n 
E 1 246 PHE 246 246 246 PHE PHE E . n 
E 1 247 LEU 247 247 247 LEU LEU E . n 
E 1 248 ASN 248 248 248 ASN ASN E . n 
E 1 249 THR 249 249 249 THR THR E . n 
E 1 250 TYR 250 250 250 TYR TYR E . n 
E 1 251 ILE 251 251 251 ILE ILE E . n 
E 1 252 VAL 252 252 252 VAL VAL E . n 
E 1 253 PRO 253 253 253 PRO PRO E . n 
E 1 254 ILE 254 254 254 ILE ILE E . n 
E 1 255 TYR 255 255 255 TYR TYR E . n 
E 1 256 PRO 256 256 256 PRO PRO E . n 
E 1 257 ASP 257 257 257 ASP ASP E . n 
E 1 258 GLU 258 258 258 GLU GLU E . n 
E 1 259 THR 259 259 259 THR THR E . n 
E 1 260 CYS 260 260 260 CYS CYS E . n 
E 1 261 TRP 261 261 261 TRP TRP E . n 
E 1 262 VAL 262 262 262 VAL VAL E . n 
E 1 263 ASN 263 263 263 ASN ASN E . n 
E 1 264 ASP 264 264 264 ASP ASP E . n 
E 1 265 PHE 265 265 265 PHE PHE E . n 
E 1 266 PRO 266 266 266 PRO PRO E . n 
E 1 267 ASN 267 267 267 ASN ASN E . n 
E 1 268 ALA 268 268 268 ALA ALA E . n 
E 1 269 ARG 269 269 269 ARG ARG E . n 
E 1 270 THR 270 270 270 THR THR E . n 
E 1 271 GLU 271 271 271 GLU GLU E . n 
E 1 272 ILE 272 272 272 ILE ILE E . n 
E 1 273 TYR 273 273 273 TYR TYR E . n 
E 1 274 THR 274 274 274 THR THR E . n 
E 1 275 ARG 275 275 275 ARG ARG E . n 
E 1 276 MET 276 276 276 MET MET E . n 
E 1 277 TYR 277 277 277 TYR TYR E . n 
E 1 278 PHE 278 278 278 PHE PHE E . n 
E 1 279 ASN 279 279 279 ASN ASN E . n 
E 1 280 HIS 280 280 280 HIS HIS E . n 
E 1 281 PRO 281 281 281 PRO PRO E . n 
E 1 282 GLY 282 282 282 GLY GLY E . n 
E 1 283 TYR 283 283 283 TYR TYR E . n 
E 1 284 ASP 284 284 284 ASP ASP E . n 
E 1 285 ASP 285 285 285 ASP ASP E . n 
E 1 286 TYR 286 286 286 TYR TYR E . n 
E 1 287 PRO 287 287 287 PRO PRO E . n 
E 1 288 VAL 288 288 288 VAL VAL E . n 
E 1 289 VAL 289 289 289 VAL VAL E . n 
E 1 290 GLY 290 290 290 GLY GLY E . n 
E 1 291 ILE 291 291 291 ILE ILE E . n 
E 1 292 SER 292 292 292 SER SER E . n 
E 1 293 TRP 293 293 293 TRP TRP E . n 
E 1 294 GLU 294 294 294 GLU GLU E . n 
E 1 295 GLN 295 295 295 GLN GLN E . n 
E 1 296 ALA 296 296 296 ALA ALA E . n 
E 1 297 GLN 297 297 297 GLN GLN E . n 
E 1 298 ALA 298 298 298 ALA ALA E . n 
E 1 299 PHE 299 299 299 PHE PHE E . n 
E 1 300 CYS 300 300 300 CYS CYS E . n 
E 1 301 ALA 301 301 301 ALA ALA E . n 
E 1 302 TRP 302 302 302 TRP TRP E . n 
E 1 303 ARG 303 303 303 ARG ARG E . n 
E 1 304 SER 304 304 304 SER SER E . n 
E 1 305 GLU 305 305 305 GLU GLU E . n 
E 1 306 PHE 306 306 306 PHE PHE E . n 
E 1 307 PHE 307 307 307 PHE PHE E . n 
E 1 308 ARG 308 308 308 ARG ARG E . n 
E 1 309 LYS 309 309 309 LYS LYS E . n 
E 1 310 GLY 310 310 310 GLY GLY E . n 
E 1 311 ILE 311 311 311 ILE ILE E . n 
E 1 312 ARG 312 312 312 ARG ARG E . n 
E 1 313 LEU 313 313 313 LEU LEU E . n 
E 1 314 PRO 314 314 314 PRO PRO E . n 
E 1 315 GLU 315 315 315 GLU GLU E . n 
E 1 316 GLY 316 316 316 GLY GLY E . n 
E 1 317 GLN 317 317 317 GLN GLN E . n 
E 1 318 ILE 318 318 318 ILE ILE E . n 
E 1 319 MET 319 319 319 MET MET E . n 
E 1 320 ASP 320 320 320 ASP ASP E . n 
E 1 321 ASP 321 321 321 ASP ASP E . n 
E 1 322 PHE 322 322 322 PHE PHE E . n 
E 1 323 ARG 323 323 323 ARG ARG E . n 
E 1 324 LEU 324 324 324 LEU LEU E . n 
E 1 325 PRO 325 325 325 PRO PRO E . n 
E 1 326 THR 326 326 326 THR THR E . n 
E 1 327 GLU 327 327 327 GLU GLU E . n 
E 1 328 ALA 328 328 328 ALA ALA E . n 
E 1 329 GLU 329 329 329 GLU GLU E . n 
E 1 330 TRP 330 330 330 TRP TRP E . n 
E 1 331 GLU 331 331 331 GLU GLU E . n 
E 1 332 TYR 332 332 332 TYR TYR E . n 
E 1 333 ALA 333 333 333 ALA ALA E . n 
E 1 334 ALA 334 334 334 ALA ALA E . n 
E 1 335 ARG 335 335 335 ARG ARG E . n 
E 1 336 MET 336 336 336 MET MET E . n 
E 1 337 GLY 337 337 337 GLY GLY E . n 
E 1 338 ASP 338 338 338 ASP ASP E . n 
E 1 339 SER 339 339 339 SER SER E . n 
E 1 340 ASN 340 340 340 ASN ASN E . n 
E 1 341 ASN 341 341 341 ASN ASN E . n 
E 1 342 LYS 342 342 342 LYS LYS E . n 
E 1 343 TYR 343 343 343 TYR TYR E . n 
E 1 344 PRO 344 344 344 PRO PRO E . n 
E 1 345 TRP 345 345 345 TRP TRP E . n 
E 1 346 SER 346 346 346 SER SER E . n 
E 1 347 THR 347 347 347 THR THR E . n 
E 1 348 GLU 348 348 348 GLU GLU E . n 
E 1 349 ASP 349 349 349 ASP ASP E . n 
E 1 350 LEU 350 350 350 LEU LEU E . n 
E 1 351 ARG 351 351 351 ARG ARG E . n 
E 1 352 THR 352 352 352 THR THR E . n 
E 1 353 GLY 353 353 353 GLY GLY E . n 
E 1 354 ARG 354 354 354 ARG ARG E . n 
E 1 355 GLY 355 355 355 GLY GLY E . n 
E 1 356 CYS 356 356 356 CYS CYS E . n 
E 1 357 PHE 357 357 357 PHE PHE E . n 
E 1 358 LEU 358 358 358 LEU LEU E . n 
E 1 359 GLY 359 359 359 GLY GLY E . n 
E 1 360 ASN 360 360 360 ASN ASN E . n 
E 1 361 PHE 361 361 361 PHE PHE E . n 
E 1 362 LYS 362 362 362 LYS LYS E . n 
E 1 363 PRO 363 363 363 PRO PRO E . n 
E 1 364 GLY 364 364 364 GLY GLY E . n 
E 1 365 GLU 365 365 365 GLU GLU E . n 
E 1 366 GLY 366 366 366 GLY GLY E . n 
E 1 367 ASP 367 367 367 ASP ASP E . n 
E 1 368 TYR 368 368 368 TYR TYR E . n 
E 1 369 THR 369 369 369 THR THR E . n 
E 1 370 ALA 370 370 370 ALA ALA E . n 
E 1 371 ASP 371 371 371 ASP ASP E . n 
E 1 372 GLY 372 372 372 GLY GLY E . n 
E 1 373 HIS 373 373 373 HIS HIS E . n 
E 1 374 LEU 374 374 374 LEU LEU E . n 
E 1 375 ILE 375 375 375 ILE ILE E . n 
E 1 376 PRO 376 376 376 PRO PRO E . n 
E 1 377 SER 377 377 377 SER SER E . n 
E 1 378 ARG 378 378 378 ARG ARG E . n 
E 1 379 VAL 379 379 379 VAL VAL E . n 
E 1 380 SER 380 380 380 SER SER E . n 
E 1 381 SER 381 381 381 SER SER E . n 
E 1 382 PHE 382 382 382 PHE PHE E . n 
E 1 383 SER 383 383 383 SER SER E . n 
E 1 384 PRO 384 384 384 PRO PRO E . n 
E 1 385 ASN 385 385 385 ASN ASN E . n 
E 1 386 ASP 386 386 386 ASP ASP E . n 
E 1 387 PHE 387 387 387 PHE PHE E . n 
E 1 388 GLY 388 388 388 GLY GLY E . n 
E 1 389 LEU 389 389 389 LEU LEU E . n 
E 1 390 TYR 390 390 390 TYR TYR E . n 
E 1 391 ASP 391 391 391 ASP ASP E . n 
E 1 392 MET 392 392 392 MET MET E . n 
E 1 393 ALA 393 393 393 ALA ALA E . n 
E 1 394 GLY 394 394 394 GLY GLY E . n 
E 1 395 ASN 395 395 395 ASN ASN E . n 
E 1 396 VAL 396 396 396 VAL VAL E . n 
E 1 397 ALA 397 397 397 ALA ALA E . n 
E 1 398 GLU 398 398 398 GLU GLU E . n 
E 1 399 TRP 399 399 399 TRP TRP E . n 
E 1 400 THR 400 400 400 THR THR E . n 
E 1 401 SER 401 401 401 SER SER E . n 
E 1 402 THR 402 402 402 THR THR E . n 
E 1 403 ALA 403 403 403 ALA ALA E . n 
E 1 404 PHE 404 404 404 PHE PHE E . n 
E 1 405 SER 405 405 405 SER SER E . n 
E 1 406 GLU 406 406 406 GLU GLU E . n 
E 1 407 SER 407 407 407 SER SER E . n 
E 1 408 GLY 408 408 408 GLY GLY E . n 
E 1 409 LEU 409 409 409 LEU LEU E . n 
E 1 410 LYS 410 410 410 LYS LYS E . n 
E 1 411 GLN 411 411 411 GLN GLN E . n 
E 1 412 MET 412 412 412 MET MET E . n 
E 1 413 SER 413 413 413 SER SER E . n 
E 1 414 ASP 414 414 414 ASP ASP E . n 
E 1 415 ILE 415 415 415 ILE ILE E . n 
E 1 416 ASN 416 416 416 ASN ASN E . n 
E 1 417 PRO 417 417 417 PRO PRO E . n 
E 1 418 GLU 418 418 418 GLU GLU E . n 
E 1 419 LEU 419 419 419 LEU LEU E . n 
E 1 420 GLU 420 420 420 GLU GLU E . n 
E 1 421 TYR 421 421 421 TYR TYR E . n 
E 1 422 LYS 422 422 422 LYS LYS E . n 
E 1 423 ALA 423 423 423 ALA ALA E . n 
E 1 424 ALA 424 424 424 ALA ALA E . n 
E 1 425 LEU 425 425 425 LEU LEU E . n 
E 1 426 THR 426 426 426 THR THR E . n 
E 1 427 ASP 427 427 427 ASP ASP E . n 
E 1 428 PRO 428 428 428 PRO PRO E . n 
E 1 429 TYR 429 429 429 TYR TYR E . n 
E 1 430 ILE 430 430 430 ILE ILE E . n 
E 1 431 LEU 431 431 431 LEU LEU E . n 
E 1 432 LYS 432 432 432 LYS LYS E . n 
E 1 433 GLN 433 433 433 GLN GLN E . n 
E 1 434 LYS 434 434 434 LYS LYS E . n 
E 1 435 VAL 435 435 435 VAL VAL E . n 
E 1 436 VAL 436 436 436 VAL VAL E . n 
E 1 437 ARG 437 437 437 ARG ARG E . n 
E 1 438 GLY 438 438 438 GLY GLY E . n 
E 1 439 GLY 439 439 439 GLY GLY E . n 
E 1 440 SER 440 440 440 SER SER E . n 
E 1 441 TRP 441 441 441 TRP TRP E . n 
E 1 442 LYS 442 442 442 LYS LYS E . n 
E 1 443 ASP 443 443 443 ASP ASP E . n 
E 1 444 VAL 444 444 444 VAL VAL E . n 
E 1 445 ALA 445 445 445 ALA ALA E . n 
E 1 446 ARG 446 446 446 ARG ARG E . n 
E 1 447 PHE 447 447 447 PHE PHE E . n 
E 1 448 ILE 448 448 448 ILE ILE E . n 
E 1 449 ARG 449 449 449 ARG ARG E . n 
E 1 450 SER 450 450 450 SER SER E . n 
E 1 451 ALA 451 451 451 ALA ALA E . n 
E 1 452 THR 452 452 452 THR THR E . n 
E 1 453 ARG 453 453 453 ARG ARG E . n 
E 1 454 SER 454 454 454 SER SER E . n 
E 1 455 HIS 455 455 455 HIS HIS E . n 
E 1 456 GLU 456 456 456 GLU GLU E . n 
E 1 457 TYR 457 457 457 TYR TYR E . n 
E 1 458 GLN 458 458 458 GLN GLN E . n 
E 1 459 ASN 459 459 459 ASN ASN E . n 
E 1 460 VAL 460 460 460 VAL VAL E . n 
E 1 461 GLY 461 461 461 GLY GLY E . n 
E 1 462 ARG 462 462 462 ARG ARG E . n 
E 1 463 SER 463 463 463 SER SER E . n 
E 1 464 TYR 464 464 464 TYR TYR E . n 
E 1 465 ILE 465 465 465 ILE ILE E . n 
E 1 466 GLY 466 466 466 GLY GLY E . n 
E 1 467 PHE 467 467 467 PHE PHE E . n 
E 1 468 ARG 468 468 468 ARG ARG E . n 
E 1 469 CYS 469 469 469 CYS CYS E . n 
E 1 470 VAL 470 470 470 VAL VAL E . n 
E 1 471 ARG 471 471 471 ARG ARG E . n 
E 1 472 THR 472 472 472 THR THR E . n 
E 1 473 SER 473 473 473 SER SER E . n 
E 1 474 ILE 474 474 474 ILE ILE E . n 
E 1 475 ALA 475 475 475 ALA ALA E . n 
E 1 476 PHE 476 476 476 PHE PHE E . n 
E 1 477 SER 477 477 ?   ?   ?   E . n 
E 1 478 SER 478 478 ?   ?   ?   E . n 
E 1 479 GLY 479 479 ?   ?   ?   E . n 
E 1 480 LYS 480 480 ?   ?   ?   E . n 
E 1 481 ALA 481 481 ?   ?   ?   E . n 
E 1 482 PRO 482 482 ?   ?   ?   E . n 
E 1 483 LYS 483 483 ?   ?   ?   E . n 
E 1 484 SER 484 484 ?   ?   ?   E . n 
E 1 485 SER 485 485 ?   ?   ?   E . n 
E 1 486 ARG 486 486 ?   ?   ?   E . n 
E 1 487 ARG 487 487 ?   ?   ?   E . n 
E 1 488 SER 488 488 ?   ?   ?   E . n 
E 1 489 THR 489 489 ?   ?   ?   E . n 
E 1 490 LYS 490 490 ?   ?   ?   E . n 
E 1 491 LYS 491 491 ?   ?   ?   E . n 
F 2 1   MET 1   -1  ?   ?   ?   F . n 
F 2 2   PHE 2   0   ?   ?   ?   F . n 
F 2 3   MET 3   1   ?   ?   ?   F . n 
F 2 4   LYS 4   2   ?   ?   ?   F . n 
F 2 5   VAL 5   3   ?   ?   ?   F . n 
F 2 6   PHE 6   4   ?   ?   ?   F . n 
F 2 7   LYS 7   5   ?   ?   ?   F . n 
F 2 8   ALA 8   6   ?   ?   ?   F . n 
F 2 9   VAL 9   7   ?   ?   ?   F . n 
F 2 10  ILE 10  8   ?   ?   ?   F . n 
F 2 11  GLY 11  9   ?   ?   ?   F . n 
F 2 12  ALA 12  10  ?   ?   ?   F . n 
F 2 13  ILE 13  11  ?   ?   ?   F . n 
F 2 14  LEU 14  12  ?   ?   ?   F . n 
F 2 15  ALA 15  13  ?   ?   ?   F . n 
F 2 16  ALA 16  14  ?   ?   ?   F . n 
F 2 17  THR 17  15  ?   ?   ?   F . n 
F 2 18  VAL 18  16  ?   ?   ?   F . n 
F 2 19  SER 19  17  ?   ?   ?   F . n 
F 2 20  ILE 20  18  ?   ?   ?   F . n 
F 2 21  SER 21  19  ?   ?   ?   F . n 
F 2 22  SER 22  20  ?   ?   ?   F . n 
F 2 23  VAL 23  21  ?   ?   ?   F . n 
F 2 24  ALA 24  22  ?   ?   ?   F . n 
F 2 25  GLN 25  23  ?   ?   ?   F . n 
F 2 26  GLU 26  24  ?   ?   ?   F . n 
F 2 27  ASN 27  25  ?   ?   ?   F . n 
F 2 28  THR 28  26  ?   ?   ?   F . n 
F 2 29  ASN 29  27  ?   ?   ?   F . n 
F 2 30  ASN 30  28  ?   ?   ?   F . n 
F 2 31  ARG 31  29  ?   ?   ?   F . n 
F 2 32  SER 32  30  ?   ?   ?   F . n 
F 2 33  PRO 33  31  ?   ?   ?   F . n 
F 2 34  GLN 34  32  ?   ?   ?   F . n 
F 2 35  VAL 35  33  ?   ?   ?   F . n 
F 2 36  GLY 36  34  ?   ?   ?   F . n 
F 2 37  ARG 37  35  ?   ?   ?   F . n 
F 2 38  ALA 38  36  ?   ?   ?   F . n 
F 2 39  PRO 39  37  ?   ?   ?   F . n 
F 2 40  ARG 40  38  ?   ?   ?   F . n 
F 2 41  ASN 41  39  ?   ?   ?   F . n 
F 2 42  THR 42  40  ?   ?   ?   F . n 
F 2 43  GLU 43  41  ?   ?   ?   F . n 
F 2 44  VAL 44  42  ?   ?   ?   F . n 
F 2 45  GLU 45  43  ?   ?   ?   F . n 
F 2 46  GLN 46  44  ?   ?   ?   F . n 
F 2 47  THR 47  45  ?   ?   ?   F . n 
F 2 48  THR 48  46  ?   ?   ?   F . n 
F 2 49  THR 49  47  47  THR THR F . n 
F 2 50  LEU 50  48  48  LEU LEU F . n 
F 2 51  SER 51  49  49  SER SER F . n 
F 2 52  ASN 52  50  50  ASN ASN F . n 
F 2 53  ARG 53  51  51  ARG ARG F . n 
F 2 54  ALA 54  52  52  ALA ALA F . n 
F 2 55  GLN 55  53  53  GLN GLN F . n 
F 2 56  GLU 56  54  54  GLU GLU F . n 
F 2 57  PHE 57  55  55  PHE PHE F . n 
F 2 58  ASN 58  56  56  ASN ASN F . n 
F 2 59  ARG 59  57  57  ARG ARG F . n 
F 2 60  ARG 60  58  58  ARG ARG F . n 
F 2 61  LEU 61  59  59  LEU LEU F . n 
F 2 62  THR 62  60  60  THR THR F . n 
F 2 63  GLN 63  61  61  GLN GLN F . n 
F 2 64  LYS 64  62  62  LYS LYS F . n 
F 2 65  THR 65  63  63  THR THR F . n 
F 2 66  ASP 66  64  64  ASP ASP F . n 
F 2 67  ASN 67  65  65  ASN ASN F . n 
F 2 68  ALA 68  66  66  ALA ALA F . n 
F 2 69  PRO 69  67  67  PRO PRO F . n 
F 2 70  TRP 70  68  68  TRP TRP F . n 
F 2 71  ARG 71  69  69  ARG ARG F . n 
F 2 72  ARG 72  70  70  ARG ARG F . n 
F 2 73  VAL 73  71  71  VAL VAL F . n 
F 2 74  VAL 74  72  72  VAL VAL F . n 
F 2 75  TYR 75  73  73  TYR TYR F . n 
F 2 76  ARG 76  74  74  ARG ARG F . n 
F 2 77  ARG 77  75  75  ARG ARG F . n 
F 2 78  VAL 78  76  76  VAL VAL F . n 
F 2 79  ASP 79  77  77  ASP ASP F . n 
F 2 80  LEU 80  78  78  LEU LEU F . n 
F 2 81  MET 81  79  79  MET MET F . n 
F 2 82  GLU 82  80  80  GLU GLU F . n 
F 2 83  GLU 83  81  81  GLU GLU F . n 
F 2 84  SER 84  82  82  SER SER F . n 
F 2 85  ASN 85  83  83  ASN ASN F . n 
F 2 86  ALA 86  84  84  ALA ALA F . n 
F 2 87  VAL 87  85  85  VAL VAL F . n 
F 2 88  LEU 88  86  86  LEU LEU F . n 
F 2 89  TYR 89  87  87  TYR TYR F . n 
F 2 90  TYR 90  88  88  TYR TYR F . n 
F 2 91  PRO 91  89  89  PRO PRO F . n 
F 2 92  PRO 92  90  90  PRO PRO F . n 
F 2 93  ARG 93  91  91  ARG ARG F . n 
F 2 94  PRO 94  92  92  PRO PRO F . n 
F 2 95  ILE 95  93  93  ILE ILE F . n 
F 2 96  GLY 96  94  94  GLY GLY F . n 
F 2 97  ASP 97  95  95  ASP ASP F . n 
F 2 98  ARG 98  96  96  ARG ARG F . n 
F 2 99  LYS 99  97  97  LYS LYS F . n 
F 2 100 ASN 100 98  98  ASN ASN F . n 
F 2 101 LEU 101 99  99  LEU LEU F . n 
F 2 102 PHE 102 100 100 PHE PHE F . n 
F 2 103 SER 103 101 101 SER SER F . n 
F 2 104 THR 104 102 102 THR THR F . n 
F 2 105 ILE 105 103 103 ILE ILE F . n 
F 2 106 PHE 106 104 104 PHE PHE F . n 
F 2 107 GLY 107 105 105 GLY GLY F . n 
F 2 108 LEU 108 106 106 LEU LEU F . n 
F 2 109 ILE 109 107 107 ILE ILE F . n 
F 2 110 ASN 110 108 108 ASN ASN F . n 
F 2 111 SER 111 109 109 SER SER F . n 
F 2 112 ASN 112 110 110 ASN ASN F . n 
F 2 113 SER 113 111 111 SER SER F . n 
F 2 114 LEU 114 112 112 LEU LEU F . n 
F 2 115 ASP 115 113 113 ASP ASP F . n 
F 2 116 VAL 116 114 114 VAL VAL F . n 
F 2 117 TYR 117 115 115 TYR TYR F . n 
F 2 118 GLU 118 116 116 GLU GLU F . n 
F 2 119 TYR 119 117 117 TYR TYR F . n 
F 2 120 LEU 120 118 118 LEU LEU F . n 
F 2 121 ASP 121 119 119 ASP ASP F . n 
F 2 122 GLY 122 120 120 GLY GLY F . n 
F 2 123 PHE 123 121 121 PHE PHE F . n 
F 2 124 GLU 124 122 122 GLU GLU F . n 
F 2 125 ALA 125 123 123 ALA ALA F . n 
F 2 126 PHE 126 124 124 PHE PHE F . n 
F 2 127 THR 127 125 125 THR THR F . n 
F 2 128 ASP 128 126 126 ASP ASP F . n 
F 2 129 GLN 129 127 127 GLN GLN F . n 
F 2 130 TYR 130 128 128 TYR TYR F . n 
F 2 131 LYS 131 129 129 LYS LYS F . n 
F 2 132 ILE 132 130 130 ILE ILE F . n 
F 2 133 LYS 133 131 131 LYS LYS F . n 
F 2 134 PHE 134 132 132 PHE PHE F . n 
F 2 135 GLN 135 133 133 GLN GLN F . n 
F 2 136 GLU 136 134 134 GLU GLU F . n 
F 2 137 PHE 137 135 135 PHE PHE F . n 
F 2 138 LEU 138 136 136 LEU LEU F . n 
F 2 139 ASP 139 137 137 ASP ASP F . n 
F 2 140 ARG 140 138 138 ARG ARG F . n 
F 2 141 PHE 141 139 139 PHE PHE F . n 
F 2 142 GLY 142 140 140 GLY GLY F . n 
F 2 143 ILE 143 141 141 ILE ILE F . n 
F 2 144 TYR 144 142 142 TYR TYR F . n 
F 2 145 TYR 145 143 143 TYR TYR F . n 
F 2 146 GLN 146 144 144 GLN GLN F . n 
F 2 147 PRO 147 145 145 PRO PRO F . n 
F 2 148 SER 148 146 146 SER SER F . n 
F 2 149 THR 149 147 147 THR THR F . n 
F 2 150 ASN 150 148 148 ASN ASN F . n 
F 2 151 LYS 151 149 149 LYS LYS F . n 
F 2 152 ASN 152 150 150 ASN ASN F . n 
F 2 153 ALA 153 151 151 ALA ALA F . n 
F 2 154 GLU 154 152 152 GLU GLU F . n 
F 2 155 LEU 155 153 153 LEU LEU F . n 
F 2 156 PHE 156 154 154 PHE PHE F . n 
F 2 157 LYS 157 155 155 LYS LYS F . n 
F 2 158 VAL 158 156 156 VAL VAL F . n 
F 2 159 ALA 159 157 157 ALA ALA F . n 
F 2 160 ASP 160 158 158 ASP ASP F . n 
F 2 161 SER 161 159 159 SER SER F . n 
F 2 162 ASP 162 160 160 ASP ASP F . n 
F 2 163 ILE 163 161 161 ILE ILE F . n 
F 2 164 PRO 164 162 162 PRO PRO F . n 
F 2 165 SER 165 163 163 SER SER F . n 
F 2 166 ALA 166 164 164 ALA ALA F . n 
F 2 167 GLU 167 165 165 GLU GLU F . n 
F 2 168 VAL 168 166 166 VAL VAL F . n 
F 2 169 LYS 169 167 167 LYS LYS F . n 
F 2 170 ALA 170 168 168 ALA ALA F . n 
F 2 171 TYR 171 169 169 TYR TYR F . n 
F 2 172 TYR 172 170 170 TYR TYR F . n 
F 2 173 VAL 173 171 171 VAL VAL F . n 
F 2 174 LYS 174 172 172 LYS LYS F . n 
F 2 175 GLU 175 173 173 GLU GLU F . n 
F 2 176 GLU 176 174 174 GLU GLU F . n 
F 2 177 TRP 177 175 175 TRP TRP F . n 
F 2 178 TYR 178 176 176 TYR TYR F . n 
F 2 179 PHE 179 177 177 PHE PHE F . n 
F 2 180 THR 180 178 178 THR THR F . n 
F 2 181 PRO 181 179 179 PRO PRO F . n 
F 2 182 THR 182 180 180 THR THR F . n 
F 2 183 ASN 183 181 181 ASN ASN F . n 
F 2 184 SER 184 182 182 SER SER F . n 
F 2 185 ASP 185 183 183 ASP ASP F . n 
F 2 186 VAL 186 184 184 VAL VAL F . n 
F 2 187 ASP 187 185 185 ASP ASP F . n 
F 2 188 ILE 188 186 186 ILE ILE F . n 
F 2 189 LYS 189 187 187 LYS LYS F . n 
F 2 190 ILE 190 188 188 ILE ILE F . n 
F 2 191 GLN 191 189 189 GLN GLN F . n 
F 2 192 ALA 192 190 190 ALA ALA F . n 
F 2 193 ILE 193 191 191 ILE ILE F . n 
F 2 194 CYS 194 192 192 CYS CYS F . n 
F 2 195 PRO 195 193 193 PRO PRO F . n 
F 2 196 ILE 196 194 194 ILE ILE F . n 
F 2 197 MET 197 195 195 MET MET F . n 
F 2 198 THR 198 196 196 THR THR F . n 
F 2 199 GLY 199 197 197 GLY GLY F . n 
F 2 200 GLN 200 198 198 GLN GLN F . n 
F 2 201 ASP 201 199 199 ASP ASP F . n 
F 2 202 GLU 202 200 200 GLU GLU F . n 
F 2 203 PHE 203 201 201 PHE PHE F . n 
F 2 204 GLY 204 202 202 GLY GLY F . n 
F 2 205 GLU 205 203 203 GLU GLU F . n 
F 2 206 VAL 206 204 204 VAL VAL F . n 
F 2 207 ARG 207 205 205 ARG ARG F . n 
F 2 208 ASN 208 206 206 ASN ASN F . n 
F 2 209 GLN 209 207 207 GLN GLN F . n 
F 2 210 PRO 210 208 208 PRO PRO F . n 
F 2 211 LEU 211 209 209 LEU LEU F . n 
F 2 212 PHE 212 210 210 PHE PHE F . n 
F 2 213 TRP 213 211 211 TRP TRP F . n 
F 2 214 ILE 214 212 212 ILE ILE F . n 
F 2 215 PRO 215 213 213 PRO PRO F . n 
F 2 216 TYR 216 214 214 TYR TYR F . n 
F 2 217 GLU 217 215 215 GLU GLU F . n 
F 2 218 ASN 218 216 216 ASN ASN F . n 
F 2 219 ILE 219 217 217 ILE ILE F . n 
F 2 220 ARG 220 218 218 ARG ARG F . n 
F 2 221 PRO 221 219 219 PRO PRO F . n 
F 2 222 TYR 222 220 220 TYR TYR F . n 
F 2 223 ILE 223 221 221 ILE ILE F . n 
F 2 224 ALA 224 222 222 ALA ALA F . n 
F 2 225 ARG 225 223 223 ARG ARG F . n 
F 2 226 GLU 226 224 224 GLU GLU F . n 
F 2 227 ARG 227 225 225 ARG ARG F . n 
F 2 228 VAL 228 226 226 VAL VAL F . n 
F 2 229 MET 229 227 227 MET MET F . n 
F 2 230 LEU 230 228 228 LEU LEU F . n 
F 2 231 SER 231 229 229 SER SER F . n 
F 2 232 SER 232 230 230 SER SER F . n 
F 2 233 LEU 233 231 231 LEU LEU F . n 
F 2 234 ASN 234 232 232 ASN ASN F . n 
F 2 235 ASN 235 233 233 ASN ASN F . n 
F 2 236 THR 236 234 234 THR THR F . n 
F 2 237 ARG 237 235 235 ARG ARG F . n 
F 2 238 ASN 238 236 236 ASN ASN F . n 
F 2 239 SER 239 237 237 SER SER F . n 
F 2 240 THR 240 238 238 THR THR F . n 
F 2 241 ILE 241 239 239 ILE ILE F . n 
F 2 242 ASP 242 240 240 ASP ASP F . n 
F 2 243 ASP 243 241 241 ASP ASP F . n 
F 2 244 PHE 244 242 242 PHE PHE F . n 
F 2 245 PHE 245 243 243 PHE PHE F . n 
F 2 246 ARG 246 244 244 ARG ARG F . n 
F 2 247 LEU 247 245 245 LEU LEU F . n 
F 2 248 ASN 248 246 246 ASN ASN F . n 
F 2 249 LEU 249 247 247 LEU LEU F . n 
F 2 250 TYR 250 248 248 TYR TYR F . n 
F 2 251 LYS 251 249 249 LYS LYS F . n 
F 2 252 GLY 252 250 250 GLY GLY F . n 
F 2 253 ASP 253 251 251 ASP ASP F . n 
F 2 254 ILE 254 252 252 ILE ILE F . n 
F 2 255 VAL 255 253 253 VAL VAL F . n 
F 2 256 LYS 256 254 254 LYS LYS F . n 
F 2 257 THR 257 255 255 THR THR F . n 
F 2 258 GLU 258 256 256 GLU GLU F . n 
F 2 259 ASN 259 257 257 ASN ASN F . n 
F 2 260 LEU 260 258 258 LEU LEU F . n 
F 2 261 HIS 261 259 259 HIS HIS F . n 
F 2 262 ASN 262 260 260 ASN ASN F . n 
F 2 263 ARG 263 261 261 ARG ARG F . n 
F 2 264 ALA 264 262 262 ALA ALA F . n 
F 2 265 LEU 265 263 263 LEU LEU F . n 
F 2 266 ALA 266 264 264 ALA ALA F . n 
F 2 267 GLU 267 265 265 GLU GLU F . n 
F 2 268 TYR 268 266 266 TYR TYR F . n 
F 2 269 CYS 269 267 267 CYS CYS F . n 
F 2 270 PRO 270 268 268 PRO PRO F . n 
F 2 271 THR 271 269 269 THR THR F . n 
F 2 272 PRO 272 270 270 PRO PRO F . n 
F 2 273 ASP 273 271 271 ASP ASP F . n 
F 2 274 SER 274 272 272 SER SER F . n 
F 2 275 MET 275 273 273 MET MET F . n 
F 2 276 LYS 276 274 274 LYS LYS F . n 
F 2 277 MET 277 275 275 MET MET F . n 
F 2 278 GLU 278 276 276 GLU GLU F . n 
F 2 279 SER 279 277 277 SER SER F . n 
F 2 280 LYS 280 278 278 LYS LYS F . n 
F 2 281 ARG 281 279 279 ARG ARG F . n 
F 2 282 ILE 282 280 280 ILE ILE F . n 
F 2 283 ASP 283 281 281 ASP ASP F . n 
F 2 284 LYS 284 282 282 LYS LYS F . n 
F 2 285 GLU 285 283 283 GLU GLU F . n 
F 2 286 LEU 286 284 284 LEU LEU F . n 
F 2 287 GLN 287 285 285 GLN GLN F . n 
F 2 288 GLY 288 286 286 GLY GLY F . n 
F 2 289 PHE 289 287 287 PHE PHE F . n 
F 2 290 ARG 290 288 288 ARG ARG F . n 
F 2 291 ASP 291 289 289 ASP ASP F . n 
F 2 292 GLY 292 290 290 GLY GLY F . n 
F 2 293 LEU 293 291 291 LEU LEU F . n 
F 2 294 PHE 294 292 292 PHE PHE F . n 
F 2 295 VAL 295 293 293 VAL VAL F . n 
F 2 296 THR 296 294 294 THR THR F . n 
F 2 297 GLN 297 295 295 GLN GLN F . n 
F 2 298 ASP 298 296 296 ASP ASP F . n 
F 2 299 THR 299 297 297 THR THR F . n 
F 2 300 THR 300 298 298 THR THR F . n 
F 2 301 TRP 301 299 299 TRP TRP F . n 
F 2 302 MET 302 300 ?   ?   ?   F . n 
F 2 303 LYS 303 301 ?   ?   ?   F . n 
F 2 304 GLN 304 302 ?   ?   ?   F . n 
F 2 305 ALA 305 303 ?   ?   ?   F . n 
F 2 306 GLU 306 304 ?   ?   ?   F . n 
F 2 307 THR 307 305 ?   ?   ?   F . n 
F 2 308 LYS 308 306 ?   ?   ?   F . n 
F 2 309 LYS 309 307 ?   ?   ?   F . n 
F 2 310 SER 310 308 ?   ?   ?   F . n 
F 2 311 LYS 311 309 ?   ?   ?   F . n 
F 2 312 GLY 312 310 ?   ?   ?   F . n 
F 2 313 LYS 313 311 ?   ?   ?   F . n 
F 2 314 LYS 314 312 ?   ?   ?   F . n 
F 2 315 LEU 315 313 ?   ?   ?   F . n 
F 2 316 GLU 316 314 ?   ?   ?   F . n 
F 2 317 LYS 317 315 ?   ?   ?   F . n 
F 2 318 ALA 318 316 ?   ?   ?   F . n 
F 2 319 ARG 319 317 ?   ?   ?   F . n 
F 2 320 GLY 320 318 ?   ?   ?   F . n 
F 2 321 LYS 321 319 ?   ?   ?   F . n 
F 2 322 ASN 322 320 ?   ?   ?   F . n 
F 2 323 ILE 323 321 ?   ?   ?   F . n 
F 2 324 THR 324 322 ?   ?   ?   F . n 
F 2 325 SER 325 323 ?   ?   ?   F . n 
F 2 326 ARG 326 324 ?   ?   ?   F . n 
F 2 327 THR 327 325 ?   ?   ?   F . n 
F 2 328 ARG 328 326 ?   ?   ?   F . n 
F 2 329 GLY 329 327 ?   ?   ?   F . n 
F 2 330 GLN 330 328 ?   ?   ?   F . n 
F 2 331 GLY 331 329 ?   ?   ?   F . n 
F 2 332 GLU 332 330 ?   ?   ?   F . n 
F 2 333 GLY 333 331 ?   ?   ?   F . n 
F 2 334 ALA 334 332 ?   ?   ?   F . n 
F 2 335 ALA 335 333 ?   ?   ?   F . n 
F 2 336 GLU 336 334 ?   ?   ?   F . n 
F 2 337 THR 337 335 ?   ?   ?   F . n 
F 2 338 GLU 338 336 ?   ?   ?   F . n 
F 2 339 ALA 339 337 ?   ?   ?   F . n 
F 2 340 VAL 340 338 ?   ?   ?   F . n 
F 2 341 GLU 341 339 ?   ?   ?   F . n 
F 2 342 PRO 342 340 ?   ?   ?   F . n 
F 2 343 LYS 343 341 ?   ?   ?   F . n 
F 2 344 LYS 344 342 ?   ?   ?   F . n 
F 2 345 GLN 345 343 ?   ?   ?   F . n 
F 2 346 LYS 346 344 ?   ?   ?   F . n 
F 2 347 ALA 347 345 ?   ?   ?   F . n 
F 2 348 SER 348 346 ?   ?   ?   F . n 
F 2 349 LYS 349 347 ?   ?   ?   F . n 
F 2 350 ASN 350 348 ?   ?   ?   F . n 
F 2 351 LYS 351 349 ?   ?   ?   F . n 
F 2 352 ALA 352 350 ?   ?   ?   F . n 
F 2 353 ALA 353 351 ?   ?   ?   F . n 
F 2 354 THR 354 352 ?   ?   ?   F . n 
F 2 355 ARG 355 353 ?   ?   ?   F . n 
F 2 356 SER 356 354 ?   ?   ?   F . n 
F 2 357 VAL 357 355 ?   ?   ?   F . n 
F 2 358 ARG 358 356 ?   ?   ?   F . n 
F 2 359 ARG 359 357 ?   ?   ?   F . n 
F 2 360 ARG 360 358 ?   ?   ?   F . n 
F 2 361 LYS 361 359 ?   ?   ?   F . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
G 3 MAN 1 G MAN 1 A MAN 501 n 
G 3 GCU 2 G GCU 2 A GCU 503 n 
G 3 GLC 3 G GLC 3 A GLC 504 n 
G 3 FUC 4 G FUC 4 A FUC 505 n 
G 3 RAM 5 G RAM 5 A RAM 502 n 
H 3 MAN 1 H MAN 1 A MAN 511 n 
H 3 GCU 2 H GCU 2 A GCU 513 n 
H 3 GLC 3 H GLC 3 A GLC 514 n 
H 3 FUC 4 H FUC 4 A FUC 515 n 
H 3 RAM 5 H RAM 5 A RAM 512 n 
I 3 MAN 1 I MAN 1 C MAN 501 n 
I 3 GCU 2 I GCU 2 C GCU 503 n 
I 3 GLC 3 I GLC 3 C GLC 504 n 
I 3 FUC 4 I FUC 4 C FUC 505 n 
I 3 RAM 5 I RAM 5 C RAM 502 n 
J 3 MAN 1 J MAN 1 C MAN 511 n 
J 3 GCU 2 J GCU 2 C GCU 513 n 
J 3 GLC 3 J GLC 3 C GLC 514 n 
J 3 FUC 4 J FUC 4 C FUC 515 n 
J 3 RAM 5 J RAM 5 C RAM 512 n 
K 3 MAN 1 K MAN 1 E MAN 501 n 
K 3 GCU 2 K GCU 2 E GCU 503 n 
K 3 GLC 3 K GLC 3 E GLC 504 n 
K 3 FUC 4 K FUC 4 E FUC 505 n 
K 3 RAM 5 K RAM 5 E RAM 502 n 
L 3 MAN 1 L MAN 1 E MAN 511 n 
L 3 GCU 2 L GCU 2 E GCU 513 n 
L 3 GLC 3 L GLC 3 E GLC 514 n 
L 3 FUC 4 L FUC 4 E FUC 515 n 
L 3 RAM 5 L RAM 5 E RAM 512 n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
M 4 CA  1 501 517 CA  CA  A . 
N 5 MAN 1 401 301 MAN MAN B . 
O 5 MAN 1 402 302 MAN MAN B . 
P 4 CA  1 501 517 CA  CA  C . 
Q 5 MAN 1 401 301 MAN MAN D . 
R 5 MAN 1 402 302 MAN MAN D . 
S 4 CA  1 501 519 CA  CA  E . 
T 5 MAN 1 401 301 MAN MAN F . 
U 5 MAN 1 402 302 MAN MAN F . 
V 6 HOH 1 601 518 HOH HOH A . 
W 6 HOH 1 601 518 HOH HOH C . 
X 6 HOH 1 601 518 HOH HOH E . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 N 1 B MAN 402 ? O1 ? O MAN 1 O1 
2 1 N 1 D MAN 402 ? O1 ? R MAN 1 O1 
3 1 N 1 F MAN 402 ? O1 ? U MAN 1 O1 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MZU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MZU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MZU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9MZU 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.40 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               NONE 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 17988 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.481 ? 24429 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.346 ? 3117  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 2649  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 3147  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9MZU 
_struct.title                        'Structure of PorKN from Porphyromonas gingivalis' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MZU 
_struct_keywords.text            
'T9SS Type 9 Secretion System C33 assembly periplasmic assembly membrane protein, PROTEIN TRANSPORT' 
_struct_keywords.pdbx_keywords   'PROTEIN TRANSPORT' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 1 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
J N N 3 ? 
K N N 3 ? 
L N N 3 ? 
M N N 4 ? 
N N N 5 ? 
O N N 5 ? 
P N N 4 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 4 ? 
T N N 5 ? 
U N N 5 ? 
V N N 6 ? 
W N N 6 ? 
X N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q7MXB7_PORGI Q7MXB7 ? 1 
;MCRKNRFFALAGFFLFGVFTISSCGSSKRAVGGELTGAKLSSWNEPSPFGMIQVPRGSIVLGNKEADSLWGIPAESRPIS
VDAFWMDRTEITNAQYRQFVYYVRDSIIRERLADPAYGGNEEYKITENKFGEPVTPHLDWSKPIPSEKRATEEEIAAINS
VYYTNPVTHDRKLNPDQMVYRYEVYDYRSAALREHQLKAAKRNLNTDIKVDPNAVVMISKDTAFVDESGNIISETITRPL
SSEYDFLNTYIVPIYPDETCWVNDFPNARTEIYTRMYFNHPGYDDYPVVGISWEQAQAFCAWRSEFFRKGIRLPEGQIMD
DFRLPTEAEWEYAARMGDSNNKYPWSTEDLRTGRGCFLGNFKPGEGDYTADGHLIPSRVSSFSPNDFGLYDMAGNVAEWT
STAFSESGLKQMSDINPELEYKAALTDPYILKQKVVRGGSWKDVARFIRSATRSHEYQNVGRSYIGFRCVRTSIAFSSGK
APKSSRRSTKK
;
1 
2 UNP Q7MXB4_PORGI Q7MXB4 ? 2 
;MFMKVFKAVIGAILAATVSISSVAQENTNNRSPQVGRAPRNTEVEQTTTLSNRAQEFNRRLTQKTDNAPWRRVVYRRVDL
MEESNAVLYYPPRPIGDRKNLFSTIFGLINSNSLDVYEYLDGFEAFTDQYKIKFQEFLDRFGIYYQPSTNKNAELFKVAD
SDIPSAEVKAYYVKEEWYFTPTNSDVDIKIQAICPIMTGQDEFGEVRNQPLFWIPYENIRPYIARERVMLSSLNNTRNST
IDDFFRLNLYKGDIVKTENLHNRALAEYCPTPDSMKMESKRIDKELQGFRDGLFVTQDTTWMKQAETKKSKGKKLEKARG
KNITSRTRGQGEGAAETEAVEPKKQKASKNKAATRSVRRRK
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9MZU A 1 ? 491 ? Q7MXB7 1 ? 491 ? 1  491 
2 2 9MZU B 1 ? 361 ? Q7MXB4 1 ? 361 ? -1 359 
3 1 9MZU C 1 ? 491 ? Q7MXB7 1 ? 491 ? 1  491 
4 2 9MZU D 1 ? 361 ? Q7MXB4 1 ? 361 ? -1 359 
5 1 9MZU E 1 ? 491 ? Q7MXB7 1 ? 491 ? 1  491 
6 2 9MZU F 1 ? 361 ? Q7MXB4 1 ? 361 ? -1 359 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 92  ? ALA A 113 ? THR A 92  ALA A 113 1 ? 22 
HELX_P HELX_P2  AA2 ASN A 120 ? GLU A 122 ? ASN A 120 GLU A 122 5 ? 3  
HELX_P HELX_P3  AA3 THR A 151 ? SER A 160 ? THR A 151 SER A 160 1 ? 10 
HELX_P HELX_P4  AA4 ASP A 186 ? ALA A 191 ? ASP A 186 ALA A 191 1 ? 6  
HELX_P HELX_P5  AA5 LEU A 192 ? GLN A 196 ? LEU A 192 GLN A 196 5 ? 5  
HELX_P HELX_P6  AA6 LYS A 198 ? ASN A 203 ? LYS A 198 ASN A 203 5 ? 6  
HELX_P HELX_P7  AA7 SER A 242 ? ASP A 245 ? SER A 242 ASP A 245 5 ? 4  
HELX_P HELX_P8  AA8 THR A 259 ? PHE A 265 ? THR A 259 PHE A 265 1 ? 7  
HELX_P HELX_P9  AA9 THR A 270 ? TYR A 277 ? THR A 270 TYR A 277 1 ? 8  
HELX_P HELX_P10 AB1 HIS A 280 ? ASP A 284 ? HIS A 280 ASP A 284 5 ? 5  
HELX_P HELX_P11 AB2 SER A 292 ? GLY A 310 ? SER A 292 GLY A 310 1 ? 19 
HELX_P HELX_P12 AB3 THR A 326 ? ARG A 335 ? THR A 326 ARG A 335 1 ? 10 
HELX_P HELX_P13 AB4 TYR A 368 ? GLY A 372 ? TYR A 368 GLY A 372 5 ? 5  
HELX_P HELX_P14 AB5 PRO A 428 ? LEU A 431 ? PRO A 428 LEU A 431 5 ? 4  
HELX_P HELX_P15 AB6 SER B 51  ? LEU B 61  ? SER B 49  LEU B 59  1 ? 11 
HELX_P HELX_P16 AB7 ASN B 85  ? TYR B 89  ? ASN B 83  TYR B 87  5 ? 5  
HELX_P HELX_P17 AB8 ASN B 100 ? SER B 111 ? ASN B 98  SER B 109 1 ? 12 
HELX_P HELX_P18 AB9 PHE B 134 ? ASP B 139 ? PHE B 132 ASP B 137 1 ? 6  
HELX_P HELX_P19 AC1 TYR B 216 ? ALA B 224 ? TYR B 214 ALA B 222 1 ? 9  
HELX_P HELX_P20 AC2 ILE B 241 ? LEU B 247 ? ILE B 239 LEU B 245 1 ? 7  
HELX_P HELX_P21 AC3 ALA B 264 ? TYR B 268 ? ALA B 262 TYR B 266 5 ? 5  
HELX_P HELX_P22 AC4 THR B 271 ? LEU B 293 ? THR B 269 LEU B 291 1 ? 23 
HELX_P HELX_P23 AC5 THR C 92  ? ALA C 113 ? THR C 92  ALA C 113 1 ? 22 
HELX_P HELX_P24 AC6 ASN C 120 ? GLU C 122 ? ASN C 120 GLU C 122 5 ? 3  
HELX_P HELX_P25 AC7 THR C 151 ? SER C 160 ? THR C 151 SER C 160 1 ? 10 
HELX_P HELX_P26 AC8 ASP C 186 ? LEU C 192 ? ASP C 186 LEU C 192 1 ? 7  
HELX_P HELX_P27 AC9 ARG C 193 ? GLN C 196 ? ARG C 193 GLN C 196 5 ? 4  
HELX_P HELX_P28 AD1 LYS C 198 ? ARG C 202 ? LYS C 198 ARG C 202 5 ? 5  
HELX_P HELX_P29 AD2 SER C 242 ? ASP C 245 ? SER C 242 ASP C 245 5 ? 4  
HELX_P HELX_P30 AD3 THR C 259 ? PHE C 265 ? THR C 259 PHE C 265 1 ? 7  
HELX_P HELX_P31 AD4 THR C 270 ? TYR C 277 ? THR C 270 TYR C 277 1 ? 8  
HELX_P HELX_P32 AD5 HIS C 280 ? ASP C 284 ? HIS C 280 ASP C 284 5 ? 5  
HELX_P HELX_P33 AD6 SER C 292 ? GLY C 310 ? SER C 292 GLY C 310 1 ? 19 
HELX_P HELX_P34 AD7 THR C 326 ? ARG C 335 ? THR C 326 ARG C 335 1 ? 10 
HELX_P HELX_P35 AD8 TYR C 368 ? GLY C 372 ? TYR C 368 GLY C 372 5 ? 5  
HELX_P HELX_P36 AD9 SER C 407 ? MET C 412 ? SER C 407 MET C 412 1 ? 6  
HELX_P HELX_P37 AE1 PRO C 428 ? LEU C 431 ? PRO C 428 LEU C 431 5 ? 4  
HELX_P HELX_P38 AE2 SER D 51  ? LEU D 61  ? SER D 49  LEU D 59  1 ? 11 
HELX_P HELX_P39 AE3 ASN D 85  ? TYR D 89  ? ASN D 83  TYR D 87  5 ? 5  
HELX_P HELX_P40 AE4 ASN D 100 ? SER D 111 ? ASN D 98  SER D 109 1 ? 12 
HELX_P HELX_P41 AE5 THR D 127 ? LYS D 131 ? THR D 125 LYS D 129 5 ? 5  
HELX_P HELX_P42 AE6 PHE D 134 ? ASP D 139 ? PHE D 132 ASP D 137 1 ? 6  
HELX_P HELX_P43 AE7 TYR D 216 ? ALA D 224 ? TYR D 214 ALA D 222 1 ? 9  
HELX_P HELX_P44 AE8 ILE D 241 ? LEU D 247 ? ILE D 239 LEU D 245 1 ? 7  
HELX_P HELX_P45 AE9 ALA D 264 ? TYR D 268 ? ALA D 262 TYR D 266 5 ? 5  
HELX_P HELX_P46 AF1 THR D 271 ? PHE D 294 ? THR D 269 PHE D 292 1 ? 24 
HELX_P HELX_P47 AF2 THR E 92  ? ALA E 113 ? THR E 92  ALA E 113 1 ? 22 
HELX_P HELX_P48 AF3 ASN E 120 ? GLU E 122 ? ASN E 120 GLU E 122 5 ? 3  
HELX_P HELX_P49 AF4 THR E 151 ? SER E 160 ? THR E 151 SER E 160 1 ? 10 
HELX_P HELX_P50 AF5 PRO E 175 ? GLN E 177 ? PRO E 175 GLN E 177 5 ? 3  
HELX_P HELX_P51 AF6 ASP E 186 ? ALA E 191 ? ASP E 186 ALA E 191 1 ? 6  
HELX_P HELX_P52 AF7 LEU E 192 ? GLN E 196 ? LEU E 192 GLN E 196 5 ? 5  
HELX_P HELX_P53 AF8 LYS E 198 ? ASN E 203 ? LYS E 198 ASN E 203 5 ? 6  
HELX_P HELX_P54 AF9 SER E 242 ? ASP E 245 ? SER E 242 ASP E 245 5 ? 4  
HELX_P HELX_P55 AG1 THR E 259 ? PHE E 265 ? THR E 259 PHE E 265 1 ? 7  
HELX_P HELX_P56 AG2 THR E 270 ? TYR E 277 ? THR E 270 TYR E 277 1 ? 8  
HELX_P HELX_P57 AG3 HIS E 280 ? ASP E 284 ? HIS E 280 ASP E 284 5 ? 5  
HELX_P HELX_P58 AG4 SER E 292 ? GLY E 310 ? SER E 292 GLY E 310 1 ? 19 
HELX_P HELX_P59 AG5 THR E 326 ? ARG E 335 ? THR E 326 ARG E 335 1 ? 10 
HELX_P HELX_P60 AG6 TYR E 368 ? GLY E 372 ? TYR E 368 GLY E 372 5 ? 5  
HELX_P HELX_P61 AG7 PRO E 428 ? LEU E 431 ? PRO E 428 LEU E 431 5 ? 4  
HELX_P HELX_P62 AG8 SER F 51  ? LEU F 61  ? SER F 49  LEU F 59  1 ? 11 
HELX_P HELX_P63 AG9 ASN F 85  ? TYR F 89  ? ASN F 83  TYR F 87  5 ? 5  
HELX_P HELX_P64 AH1 ASN F 100 ? SER F 111 ? ASN F 98  SER F 109 1 ? 12 
HELX_P HELX_P65 AH2 PHE F 134 ? ASP F 139 ? PHE F 132 ASP F 137 1 ? 6  
HELX_P HELX_P66 AH3 TYR F 216 ? ALA F 224 ? TYR F 214 ALA F 222 1 ? 9  
HELX_P HELX_P67 AH4 ILE F 241 ? LEU F 247 ? ILE F 239 LEU F 245 1 ? 7  
HELX_P HELX_P68 AH5 ALA F 264 ? CYS F 269 ? ALA F 262 CYS F 267 5 ? 6  
HELX_P HELX_P69 AH6 THR F 271 ? LEU F 293 ? THR F 269 LEU F 291 1 ? 23 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale one  ? A SER 106 OG  ? ? ? 1_555 G MAN . C1 ? ? A SER 106 G MAN 1   1_555 ? ? ? ? ? ? ? 1.434 ? O-Glycosylation 
covale2  covale one  ? A THR 222 OG1 ? ? ? 1_555 H MAN . C1 ? ? A THR 222 H MAN 1   1_555 ? ? ? ? ? ? ? 1.444 ? O-Glycosylation 
covale3  covale one  ? B SER 274 OG  ? ? ? 1_555 N MAN . C1 ? ? B SER 272 B MAN 401 1_555 ? ? ? ? ? ? ? 1.439 ? O-Glycosylation 
covale4  covale one  ? C SER 106 OG  ? ? ? 1_555 I MAN . C1 ? ? C SER 106 I MAN 1   1_555 ? ? ? ? ? ? ? 1.435 ? O-Glycosylation 
covale5  covale one  ? C THR 222 OG1 ? ? ? 1_555 J MAN . C1 ? ? C THR 222 J MAN 1   1_555 ? ? ? ? ? ? ? 1.443 ? O-Glycosylation 
covale6  covale one  ? D SER 274 OG  ? ? ? 1_555 Q MAN . C1 ? ? D SER 272 D MAN 401 1_555 ? ? ? ? ? ? ? 1.439 ? O-Glycosylation 
covale7  covale one  ? E SER 106 OG  ? ? ? 1_555 K MAN . C1 ? ? E SER 106 K MAN 1   1_555 ? ? ? ? ? ? ? 1.435 ? O-Glycosylation 
covale8  covale one  ? E THR 222 OG1 ? ? ? 1_555 L MAN . C1 ? ? E THR 222 L MAN 1   1_555 ? ? ? ? ? ? ? 1.443 ? O-Glycosylation 
covale9  covale one  ? F SER 274 OG  ? ? ? 1_555 T MAN . C1 ? ? F SER 272 F MAN 401 1_555 ? ? ? ? ? ? ? 1.440 ? O-Glycosylation 
covale10 covale both ? G MAN .   O2  ? ? ? 1_555 G GCU . C1 ? ? G MAN 1   G GCU 2   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale11 covale both ? G MAN .   O4  ? ? ? 1_555 G RAM . C1 ? ? G MAN 1   G RAM 5   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale12 covale both ? G GCU .   O4  ? ? ? 1_555 G GLC . C1 ? ? G GCU 2   G GLC 3   1_555 ? ? ? ? ? ? ? 1.452 ? ?               
covale13 covale both ? G GLC .   O4  ? ? ? 1_555 G FUC . C1 ? ? G GLC 3   G FUC 4   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
covale14 covale both ? H MAN .   O2  ? ? ? 1_555 H GCU . C1 ? ? H MAN 1   H GCU 2   1_555 ? ? ? ? ? ? ? 1.436 ? ?               
covale15 covale both ? H MAN .   O4  ? ? ? 1_555 H RAM . C1 ? ? H MAN 1   H RAM 5   1_555 ? ? ? ? ? ? ? 1.491 ? ?               
covale16 covale both ? H GCU .   O4  ? ? ? 1_555 H GLC . C1 ? ? H GCU 2   H GLC 3   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
covale17 covale both ? H GLC .   O4  ? ? ? 1_555 H FUC . C1 ? ? H GLC 3   H FUC 4   1_555 ? ? ? ? ? ? ? 1.453 ? ?               
covale18 covale both ? I MAN .   O2  ? ? ? 1_555 I GCU . C1 ? ? I MAN 1   I GCU 2   1_555 ? ? ? ? ? ? ? 1.451 ? ?               
covale19 covale both ? I MAN .   O4  ? ? ? 1_555 I RAM . C1 ? ? I MAN 1   I RAM 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale20 covale both ? I GCU .   O4  ? ? ? 1_555 I GLC . C1 ? ? I GCU 2   I GLC 3   1_555 ? ? ? ? ? ? ? 1.453 ? ?               
covale21 covale both ? I GLC .   O4  ? ? ? 1_555 I FUC . C1 ? ? I GLC 3   I FUC 4   1_555 ? ? ? ? ? ? ? 1.453 ? ?               
covale22 covale both ? J MAN .   O2  ? ? ? 1_555 J GCU . C1 ? ? J MAN 1   J GCU 2   1_555 ? ? ? ? ? ? ? 1.437 ? ?               
covale23 covale both ? J MAN .   O4  ? ? ? 1_555 J RAM . C1 ? ? J MAN 1   J RAM 5   1_555 ? ? ? ? ? ? ? 1.491 ? ?               
covale24 covale both ? J GCU .   O4  ? ? ? 1_555 J GLC . C1 ? ? J GCU 2   J GLC 3   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale25 covale both ? J GLC .   O4  ? ? ? 1_555 J FUC . C1 ? ? J GLC 3   J FUC 4   1_555 ? ? ? ? ? ? ? 1.453 ? ?               
covale26 covale both ? K MAN .   O2  ? ? ? 1_555 K GCU . C1 ? ? K MAN 1   K GCU 2   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
covale27 covale both ? K MAN .   O4  ? ? ? 1_555 K RAM . C1 ? ? K MAN 1   K RAM 5   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale28 covale both ? K GCU .   O4  ? ? ? 1_555 K GLC . C1 ? ? K GCU 2   K GLC 3   1_555 ? ? ? ? ? ? ? 1.452 ? ?               
covale29 covale both ? K GLC .   O4  ? ? ? 1_555 K FUC . C1 ? ? K GLC 3   K FUC 4   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
covale30 covale both ? L MAN .   O2  ? ? ? 1_555 L GCU . C1 ? ? L MAN 1   L GCU 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale31 covale both ? L MAN .   O4  ? ? ? 1_555 L RAM . C1 ? ? L MAN 1   L RAM 5   1_555 ? ? ? ? ? ? ? 1.490 ? ?               
covale32 covale both ? L GCU .   O4  ? ? ? 1_555 L GLC . C1 ? ? L GCU 2   L GLC 3   1_555 ? ? ? ? ? ? ? 1.447 ? ?               
covale33 covale both ? L GLC .   O4  ? ? ? 1_555 L FUC . C1 ? ? L GLC 3   L FUC 4   1_555 ? ? ? ? ? ? ? 1.452 ? ?               
metalc1  metalc ?    ? A GLU 90  OE1 ? ? ? 1_555 M CA  . CA ? ? A GLU 90  A CA  501 1_555 ? ? ? ? ? ? ? 2.478 ? ?               
metalc2  metalc ?    ? A ASP 391 O   ? ? ? 1_555 M CA  . CA ? ? A ASP 391 A CA  501 1_555 ? ? ? ? ? ? ? 2.318 ? ?               
metalc3  metalc ?    ? A GLY 394 O   ? ? ? 1_555 M CA  . CA ? ? A GLY 394 A CA  501 1_555 ? ? ? ? ? ? ? 2.620 ? ?               
metalc4  metalc ?    ? A VAL 396 O   ? ? ? 1_555 M CA  . CA ? ? A VAL 396 A CA  501 1_555 ? ? ? ? ? ? ? 2.478 ? ?               
metalc5  metalc ?    ? A GLU 398 OE2 ? ? ? 1_555 M CA  . CA ? ? A GLU 398 A CA  501 1_555 ? ? ? ? ? ? ? 2.446 ? ?               
metalc6  metalc ?    ? M CA  .   CA  ? ? ? 1_555 V HOH . O  ? ? A CA  501 A HOH 601 1_555 ? ? ? ? ? ? ? 2.093 ? ?               
metalc7  metalc ?    ? C GLU 90  OE2 ? ? ? 1_555 P CA  . CA ? ? C GLU 90  C CA  501 1_555 ? ? ? ? ? ? ? 2.169 ? ?               
metalc8  metalc ?    ? C ASP 391 O   ? ? ? 1_555 P CA  . CA ? ? C ASP 391 C CA  501 1_555 ? ? ? ? ? ? ? 2.176 ? ?               
metalc9  metalc ?    ? C GLY 394 O   ? ? ? 1_555 P CA  . CA ? ? C GLY 394 C CA  501 1_555 ? ? ? ? ? ? ? 2.606 ? ?               
metalc10 metalc ?    ? C VAL 396 O   ? ? ? 1_555 P CA  . CA ? ? C VAL 396 C CA  501 1_555 ? ? ? ? ? ? ? 2.533 ? ?               
metalc11 metalc ?    ? C GLU 398 OE2 ? ? ? 1_555 P CA  . CA ? ? C GLU 398 C CA  501 1_555 ? ? ? ? ? ? ? 2.667 ? ?               
metalc12 metalc ?    ? P CA  .   CA  ? ? ? 1_555 W HOH . O  ? ? C CA  501 C HOH 601 1_555 ? ? ? ? ? ? ? 2.086 ? ?               
metalc13 metalc ?    ? E GLU 90  OE2 ? ? ? 1_555 S CA  . CA ? ? E GLU 90  E CA  501 1_555 ? ? ? ? ? ? ? 2.178 ? ?               
metalc14 metalc ?    ? E ASP 391 O   ? ? ? 1_555 S CA  . CA ? ? E ASP 391 E CA  501 1_555 ? ? ? ? ? ? ? 2.194 ? ?               
metalc15 metalc ?    ? E GLY 394 O   ? ? ? 1_555 S CA  . CA ? ? E GLY 394 E CA  501 1_555 ? ? ? ? ? ? ? 2.319 ? ?               
metalc16 metalc ?    ? E VAL 396 O   ? ? ? 1_555 S CA  . CA ? ? E VAL 396 E CA  501 1_555 ? ? ? ? ? ? ? 2.625 ? ?               
metalc17 metalc ?    ? E GLU 398 OE2 ? ? ? 1_555 S CA  . CA ? ? E GLU 398 E CA  501 1_555 ? ? ? ? ? ? ? 2.702 ? ?               
metalc18 metalc ?    ? S CA  .   CA  ? ? ? 1_555 X HOH . O  ? ? E CA  501 E HOH 601 1_555 ? ? ? ? ? ? ? 2.048 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE1 ? A GLU 90  ? A GLU 90  ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A ASP 391 ? A ASP 391 ? 1_555 105.1 ? 
2  OE1 ? A GLU 90  ? A GLU 90  ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A GLY 394 ? A GLY 394 ? 1_555 123.6 ? 
3  O   ? A ASP 391 ? A ASP 391 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A GLY 394 ? A GLY 394 ? 1_555 92.5  ? 
4  OE1 ? A GLU 90  ? A GLU 90  ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A VAL 396 ? A VAL 396 ? 1_555 90.1  ? 
5  O   ? A ASP 391 ? A ASP 391 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A VAL 396 ? A VAL 396 ? 1_555 163.1 ? 
6  O   ? A GLY 394 ? A GLY 394 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? A VAL 396 ? A VAL 396 ? 1_555 84.7  ? 
7  OE1 ? A GLU 90  ? A GLU 90  ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 OE2 ? A GLU 398 ? A GLU 398 ? 1_555 84.4  ? 
8  O   ? A ASP 391 ? A ASP 391 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 OE2 ? A GLU 398 ? A GLU 398 ? 1_555 84.9  ? 
9  O   ? A GLY 394 ? A GLY 394 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 OE2 ? A GLU 398 ? A GLU 398 ? 1_555 151.2 ? 
10 O   ? A VAL 396 ? A VAL 396 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 OE2 ? A GLU 398 ? A GLU 398 ? 1_555 89.5  ? 
11 OE1 ? A GLU 90  ? A GLU 90  ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? V HOH .   ? A HOH 601 ? 1_555 151.6 ? 
12 O   ? A ASP 391 ? A ASP 391 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? V HOH .   ? A HOH 601 ? 1_555 89.9  ? 
13 O   ? A GLY 394 ? A GLY 394 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? V HOH .   ? A HOH 601 ? 1_555 78.5  ? 
14 O   ? A VAL 396 ? A VAL 396 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? V HOH .   ? A HOH 601 ? 1_555 73.3  ? 
15 OE2 ? A GLU 398 ? A GLU 398 ? 1_555 CA ? M CA . ? A CA 501 ? 1_555 O   ? V HOH .   ? A HOH 601 ? 1_555 72.9  ? 
16 OE2 ? C GLU 90  ? C GLU 90  ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C ASP 391 ? C ASP 391 ? 1_555 99.9  ? 
17 OE2 ? C GLU 90  ? C GLU 90  ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C GLY 394 ? C GLY 394 ? 1_555 102.3 ? 
18 O   ? C ASP 391 ? C ASP 391 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C GLY 394 ? C GLY 394 ? 1_555 97.1  ? 
19 OE2 ? C GLU 90  ? C GLU 90  ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C VAL 396 ? C VAL 396 ? 1_555 86.6  ? 
20 O   ? C ASP 391 ? C ASP 391 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C VAL 396 ? C VAL 396 ? 1_555 173.0 ? 
21 O   ? C GLY 394 ? C GLY 394 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? C VAL 396 ? C VAL 396 ? 1_555 83.7  ? 
22 OE2 ? C GLU 90  ? C GLU 90  ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 OE2 ? C GLU 398 ? C GLU 398 ? 1_555 99.6  ? 
23 O   ? C ASP 391 ? C ASP 391 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 OE2 ? C GLU 398 ? C GLU 398 ? 1_555 87.5  ? 
24 O   ? C GLY 394 ? C GLY 394 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 OE2 ? C GLU 398 ? C GLU 398 ? 1_555 156.4 ? 
25 O   ? C VAL 396 ? C VAL 396 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 OE2 ? C GLU 398 ? C GLU 398 ? 1_555 89.1  ? 
26 OE2 ? C GLU 90  ? C GLU 90  ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? W HOH .   ? C HOH 601 ? 1_555 158.3 ? 
27 O   ? C ASP 391 ? C ASP 391 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? W HOH .   ? C HOH 601 ? 1_555 101.3 ? 
28 O   ? C GLY 394 ? C GLY 394 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? W HOH .   ? C HOH 601 ? 1_555 79.5  ? 
29 O   ? C VAL 396 ? C VAL 396 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? W HOH .   ? C HOH 601 ? 1_555 72.0  ? 
30 OE2 ? C GLU 398 ? C GLU 398 ? 1_555 CA ? P CA . ? C CA 501 ? 1_555 O   ? W HOH .   ? C HOH 601 ? 1_555 76.9  ? 
31 OE2 ? E GLU 90  ? E GLU 90  ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E ASP 391 ? E ASP 391 ? 1_555 101.0 ? 
32 OE2 ? E GLU 90  ? E GLU 90  ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E GLY 394 ? E GLY 394 ? 1_555 111.7 ? 
33 O   ? E ASP 391 ? E ASP 391 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E GLY 394 ? E GLY 394 ? 1_555 103.5 ? 
34 OE2 ? E GLU 90  ? E GLU 90  ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E VAL 396 ? E VAL 396 ? 1_555 90.1  ? 
35 O   ? E ASP 391 ? E ASP 391 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E VAL 396 ? E VAL 396 ? 1_555 158.5 ? 
36 O   ? E GLY 394 ? E GLY 394 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? E VAL 396 ? E VAL 396 ? 1_555 89.1  ? 
37 OE2 ? E GLU 90  ? E GLU 90  ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 OE2 ? E GLU 398 ? E GLU 398 ? 1_555 92.1  ? 
38 O   ? E ASP 391 ? E ASP 391 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 OE2 ? E GLU 398 ? E GLU 398 ? 1_555 83.4  ? 
39 O   ? E GLY 394 ? E GLY 394 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 OE2 ? E GLU 398 ? E GLU 398 ? 1_555 152.9 ? 
40 O   ? E VAL 396 ? E VAL 396 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 OE2 ? E GLU 398 ? E GLU 398 ? 1_555 77.8  ? 
41 OE2 ? E GLU 90  ? E GLU 90  ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? X HOH .   ? E HOH 601 ? 1_555 153.0 ? 
42 O   ? E ASP 391 ? E ASP 391 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? X HOH .   ? E HOH 601 ? 1_555 93.4  ? 
43 O   ? E GLY 394 ? E GLY 394 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? X HOH .   ? E HOH 601 ? 1_555 86.5  ? 
44 O   ? E VAL 396 ? E VAL 396 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? X HOH .   ? E HOH 601 ? 1_555 69.7  ? 
45 OE2 ? E GLU 398 ? E GLU 398 ? 1_555 CA ? S CA . ? E CA 501 ? 1_555 O   ? X HOH .   ? E HOH 601 ? 1_555 66.8  ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 MAN G . ? SER A 106 ? MAN G 1   ? 1_555 SER A 106 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
2 MAN H . ? THR A 222 ? MAN H 1   ? 1_555 THR A 222 ? 1_555 C1 OG1 THR 2 MAN O-Glycosylation Carbohydrate 
3 MAN I . ? SER C 106 ? MAN I 1   ? 1_555 SER C 106 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
4 MAN J . ? THR C 222 ? MAN J 1   ? 1_555 THR C 222 ? 1_555 C1 OG1 THR 2 MAN O-Glycosylation Carbohydrate 
5 MAN K . ? SER E 106 ? MAN K 1   ? 1_555 SER E 106 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
6 MAN L . ? THR E 222 ? MAN L 1   ? 1_555 THR E 222 ? 1_555 C1 OG1 THR 2 MAN O-Glycosylation Carbohydrate 
7 MAN N . ? SER B 274 ? MAN B 401 ? 1_555 SER B 272 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
8 MAN Q . ? SER D 274 ? MAN D 401 ? 1_555 SER D 272 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
9 MAN T . ? SER F 274 ? MAN F 401 ? 1_555 SER F 272 ? 1_555 C1 OG  SER 1 MAN O-Glycosylation Carbohydrate 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 90 B . ? TYR 88 B PRO 91 B ? PRO 89 B 1 -4.17 
2 TYR 90 D . ? TYR 88 D PRO 91 D ? PRO 89 D 1 -7.82 
3 TYR 90 F . ? TYR 88 F PRO 91 F ? PRO 89 F 1 -5.51 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 2 ? 
AB2 ? 3 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 2 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 6 ? 
AC2 ? 2 ? 
AC3 ? 2 ? 
AC4 ? 3 ? 
AC5 ? 2 ? 
AC6 ? 2 ? 
AC7 ? 2 ? 
AC8 ? 2 ? 
AC9 ? 2 ? 
AD1 ? 4 ? 
AD2 ? 4 ? 
AD3 ? 6 ? 
AD4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? parallel      
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC1 5 6 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC9 1 2 ? anti-parallel 
AD1 1 2 ? anti-parallel 
AD1 2 3 ? anti-parallel 
AD1 3 4 ? parallel      
AD2 1 2 ? anti-parallel 
AD2 2 3 ? anti-parallel 
AD2 3 4 ? anti-parallel 
AD3 1 2 ? anti-parallel 
AD3 2 3 ? anti-parallel 
AD3 3 4 ? anti-parallel 
AD3 4 5 ? anti-parallel 
AD3 5 6 ? anti-parallel 
AD4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 MET A 51  ? VAL A 54  ? MET A 51  VAL A 54  
AA1 2 PHE A 84  ? ASP A 87  ? PHE A 84  ASP A 87  
AA1 3 VAL A 470 ? THR A 472 ? VAL A 470 THR A 472 
AA2 1 GLY A 57  ? GLY A 62  ? GLY A 57  GLY A 62  
AA2 2 SER A 76  ? VAL A 81  ? SER A 76  VAL A 81  
AA3 1 LYS A 124 ? GLU A 127 ? LYS A 124 GLU A 127 
AA3 2 PRO A 133 ? LEU A 138 ? PRO A 133 LEU A 138 
AA4 1 TYR A 162 ? THR A 164 ? TYR A 162 THR A 164 
AA4 2 ARG A 171 ? LEU A 173 ? ARG A 171 LEU A 173 
AA5 1 VAL A 179 ? TYR A 185 ? VAL A 179 TYR A 185 
AA5 2 LEU A 247 ? PRO A 253 ? LEU A 247 PRO A 253 
AA6 1 MET A 217 ? VAL A 225 ? MET A 217 VAL A 225 
AA6 2 ILE A 231 ? PRO A 239 ? ILE A 231 PRO A 239 
AA7 1 ARG A 453 ? TYR A 457 ? ARG A 453 TYR A 457 
AA7 2 GLN A 433 ? ARG A 437 ? GLN A 433 ARG A 437 
AA7 3 ALA A 397 ? ALA A 403 ? ALA A 397 ALA A 403 
AA7 4 ILE A 465 ? GLY A 466 ? ILE A 465 GLY A 466 
AA8 1 TYR B 117 ? GLU B 118 ? TYR B 115 GLU B 116 
AA8 2 PHE B 212 ? PRO B 215 ? PHE B 210 PRO B 213 
AA8 3 VAL B 186 ? MET B 197 ? VAL B 184 MET B 195 
AA8 4 GLN B 209 ? PRO B 210 ? GLN B 207 PRO B 208 
AA9 1 TYR B 117 ? GLU B 118 ? TYR B 115 GLU B 116 
AA9 2 PHE B 212 ? PRO B 215 ? PHE B 210 PRO B 213 
AA9 3 VAL B 186 ? MET B 197 ? VAL B 184 MET B 195 
AA9 4 VAL B 168 ? PHE B 179 ? VAL B 166 PHE B 177 
AA9 5 ARG B 71  ? ASP B 79  ? ARG B 69  ASP B 77  
AA9 6 GLY B 252 ? THR B 257 ? GLY B 250 THR B 255 
AB1 1 ARG B 227 ? VAL B 228 ? ARG B 225 VAL B 226 
AB1 2 SER B 239 ? THR B 240 ? SER B 237 THR B 238 
AB2 1 MET C 51  ? VAL C 54  ? MET C 51  VAL C 54  
AB2 2 PHE C 84  ? ASP C 87  ? PHE C 84  ASP C 87  
AB2 3 VAL C 470 ? THR C 472 ? VAL C 470 THR C 472 
AB3 1 GLY C 57  ? GLY C 62  ? GLY C 57  GLY C 62  
AB3 2 SER C 76  ? VAL C 81  ? SER C 76  VAL C 81  
AB4 1 LYS C 124 ? GLU C 127 ? LYS C 124 GLU C 127 
AB4 2 PRO C 133 ? LEU C 138 ? PRO C 133 LEU C 138 
AB5 1 TYR C 162 ? THR C 164 ? TYR C 162 THR C 164 
AB5 2 ARG C 171 ? LEU C 173 ? ARG C 171 LEU C 173 
AB6 1 VAL C 179 ? TYR C 185 ? VAL C 179 TYR C 185 
AB6 2 LEU C 247 ? PRO C 253 ? LEU C 247 PRO C 253 
AB7 1 MET C 217 ? VAL C 225 ? MET C 217 VAL C 225 
AB7 2 ILE C 231 ? PRO C 239 ? ILE C 231 PRO C 239 
AB8 1 ARG C 453 ? TYR C 457 ? ARG C 453 TYR C 457 
AB8 2 GLN C 433 ? ARG C 437 ? GLN C 433 ARG C 437 
AB8 3 ALA C 397 ? ALA C 403 ? ALA C 397 ALA C 403 
AB8 4 ILE C 465 ? GLY C 466 ? ILE C 465 GLY C 466 
AB9 1 TYR D 117 ? GLU D 118 ? TYR D 115 GLU D 116 
AB9 2 PHE D 212 ? PRO D 215 ? PHE D 210 PRO D 213 
AB9 3 VAL D 186 ? MET D 197 ? VAL D 184 MET D 195 
AB9 4 GLN D 209 ? PRO D 210 ? GLN D 207 PRO D 208 
AC1 1 TYR D 117 ? GLU D 118 ? TYR D 115 GLU D 116 
AC1 2 PHE D 212 ? PRO D 215 ? PHE D 210 PRO D 213 
AC1 3 VAL D 186 ? MET D 197 ? VAL D 184 MET D 195 
AC1 4 VAL D 168 ? PHE D 179 ? VAL D 166 PHE D 177 
AC1 5 ARG D 71  ? ASP D 79  ? ARG D 69  ASP D 77  
AC1 6 GLY D 252 ? THR D 257 ? GLY D 250 THR D 255 
AC2 1 GLN D 146 ? PRO D 147 ? GLN D 144 PRO D 145 
AC2 2 PHE D 156 ? LYS D 157 ? PHE D 154 LYS D 155 
AC3 1 ARG D 227 ? VAL D 228 ? ARG D 225 VAL D 226 
AC3 2 SER D 239 ? THR D 240 ? SER D 237 THR D 238 
AC4 1 MET E 51  ? VAL E 54  ? MET E 51  VAL E 54  
AC4 2 PHE E 84  ? ASP E 87  ? PHE E 84  ASP E 87  
AC4 3 VAL E 470 ? THR E 472 ? VAL E 470 THR E 472 
AC5 1 GLY E 57  ? GLY E 62  ? GLY E 57  GLY E 62  
AC5 2 SER E 76  ? VAL E 81  ? SER E 76  VAL E 81  
AC6 1 LYS E 124 ? GLU E 127 ? LYS E 124 GLU E 127 
AC6 2 PRO E 133 ? LEU E 138 ? PRO E 133 LEU E 138 
AC7 1 TYR E 162 ? THR E 164 ? TYR E 162 THR E 164 
AC7 2 ARG E 171 ? LEU E 173 ? ARG E 171 LEU E 173 
AC8 1 VAL E 179 ? TYR E 185 ? VAL E 179 TYR E 185 
AC8 2 LEU E 247 ? PRO E 253 ? LEU E 247 PRO E 253 
AC9 1 MET E 217 ? VAL E 225 ? MET E 217 VAL E 225 
AC9 2 ILE E 231 ? PRO E 239 ? ILE E 231 PRO E 239 
AD1 1 ARG E 453 ? TYR E 457 ? ARG E 453 TYR E 457 
AD1 2 GLN E 433 ? ARG E 437 ? GLN E 433 ARG E 437 
AD1 3 ALA E 397 ? ALA E 403 ? ALA E 397 ALA E 403 
AD1 4 ILE E 465 ? GLY E 466 ? ILE E 465 GLY E 466 
AD2 1 TYR F 117 ? GLU F 118 ? TYR F 115 GLU F 116 
AD2 2 PHE F 212 ? PRO F 215 ? PHE F 210 PRO F 213 
AD2 3 VAL F 186 ? MET F 197 ? VAL F 184 MET F 195 
AD2 4 GLN F 209 ? PRO F 210 ? GLN F 207 PRO F 208 
AD3 1 TYR F 117 ? GLU F 118 ? TYR F 115 GLU F 116 
AD3 2 PHE F 212 ? PRO F 215 ? PHE F 210 PRO F 213 
AD3 3 VAL F 186 ? MET F 197 ? VAL F 184 MET F 195 
AD3 4 VAL F 168 ? PHE F 179 ? VAL F 166 PHE F 177 
AD3 5 ARG F 71  ? ASP F 79  ? ARG F 69  ASP F 77  
AD3 6 GLY F 252 ? THR F 257 ? GLY F 250 THR F 255 
AD4 1 ARG F 227 ? VAL F 228 ? ARG F 225 VAL F 226 
AD4 2 SER F 239 ? THR F 240 ? SER F 237 THR F 238 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 54  ? N VAL A 54  O PHE A 84  ? O PHE A 84  
AA1 2 3 N TRP A 85  ? N TRP A 85  O ARG A 471 ? O ARG A 471 
AA2 1 2 N ILE A 59  ? N ILE A 59  O ILE A 79  ? O ILE A 79  
AA3 1 2 N ILE A 125 ? N ILE A 125 O HIS A 137 ? O HIS A 137 
AA4 1 2 N TYR A 163 ? N TYR A 163 O LYS A 172 ? O LYS A 172 
AA5 1 2 N VAL A 184 ? N VAL A 184 O ASN A 248 ? O ASN A 248 
AA6 1 2 N PHE A 224 ? N PHE A 224 O ILE A 232 ? O ILE A 232 
AA7 1 2 O GLU A 456 ? O GLU A 456 N LYS A 434 ? N LYS A 434 
AA7 2 3 O ARG A 437 ? O ARG A 437 N GLU A 398 ? N GLU A 398 
AA7 3 4 N ALA A 397 ? N ALA A 397 O GLY A 466 ? O GLY A 466 
AA8 1 2 N TYR B 117 ? N TYR B 115 O TRP B 213 ? O TRP B 211 
AA8 2 3 O ILE B 214 ? O ILE B 212 N ILE B 193 ? N ILE B 191 
AA8 3 4 N MET B 197 ? N MET B 195 O GLN B 209 ? O GLN B 207 
AA9 1 2 N TYR B 117 ? N TYR B 115 O TRP B 213 ? O TRP B 211 
AA9 2 3 O ILE B 214 ? O ILE B 212 N ILE B 193 ? N ILE B 191 
AA9 3 4 O GLN B 191 ? O GLN B 189 N LYS B 174 ? N LYS B 172 
AA9 4 5 O GLU B 175 ? O GLU B 173 N VAL B 74  ? N VAL B 72  
AA9 5 6 N TYR B 75  ? N TYR B 73  O VAL B 255 ? O VAL B 253 
AB1 1 2 N VAL B 228 ? N VAL B 226 O SER B 239 ? O SER B 237 
AB2 1 2 N VAL C 54  ? N VAL C 54  O PHE C 84  ? O PHE C 84  
AB2 2 3 N TRP C 85  ? N TRP C 85  O ARG C 471 ? O ARG C 471 
AB3 1 2 N ILE C 59  ? N ILE C 59  O ILE C 79  ? O ILE C 79  
AB4 1 2 N ILE C 125 ? N ILE C 125 O HIS C 137 ? O HIS C 137 
AB5 1 2 N TYR C 163 ? N TYR C 163 O LYS C 172 ? O LYS C 172 
AB6 1 2 N VAL C 184 ? N VAL C 184 O ASN C 248 ? O ASN C 248 
AB7 1 2 N ILE C 218 ? N ILE C 218 O ARG C 238 ? O ARG C 238 
AB8 1 2 O GLU C 456 ? O GLU C 456 N LYS C 434 ? N LYS C 434 
AB8 2 3 O ARG C 437 ? O ARG C 437 N GLU C 398 ? N GLU C 398 
AB8 3 4 N ALA C 397 ? N ALA C 397 O GLY C 466 ? O GLY C 466 
AB9 1 2 N TYR D 117 ? N TYR D 115 O TRP D 213 ? O TRP D 211 
AB9 2 3 O ILE D 214 ? O ILE D 212 N ILE D 193 ? N ILE D 191 
AB9 3 4 N MET D 197 ? N MET D 195 O GLN D 209 ? O GLN D 207 
AC1 1 2 N TYR D 117 ? N TYR D 115 O TRP D 213 ? O TRP D 211 
AC1 2 3 O ILE D 214 ? O ILE D 212 N ILE D 193 ? N ILE D 191 
AC1 3 4 O GLN D 191 ? O GLN D 189 N LYS D 174 ? N LYS D 172 
AC1 4 5 O TRP D 177 ? O TRP D 175 N ARG D 72  ? N ARG D 70  
AC1 5 6 N TYR D 75  ? N TYR D 73  O VAL D 255 ? O VAL D 253 
AC2 1 2 N GLN D 146 ? N GLN D 144 O LYS D 157 ? O LYS D 155 
AC3 1 2 N VAL D 228 ? N VAL D 226 O SER D 239 ? O SER D 237 
AC4 1 2 N VAL E 54  ? N VAL E 54  O PHE E 84  ? O PHE E 84  
AC4 2 3 N TRP E 85  ? N TRP E 85  O ARG E 471 ? O ARG E 471 
AC5 1 2 N ILE E 59  ? N ILE E 59  O ILE E 79  ? O ILE E 79  
AC6 1 2 N ILE E 125 ? N ILE E 125 O HIS E 137 ? O HIS E 137 
AC7 1 2 N TYR E 163 ? N TYR E 163 O LYS E 172 ? O LYS E 172 
AC8 1 2 N VAL E 184 ? N VAL E 184 O ASN E 248 ? O ASN E 248 
AC9 1 2 N ILE E 218 ? N ILE E 218 O ARG E 238 ? O ARG E 238 
AD1 1 2 O GLU E 456 ? O GLU E 456 N LYS E 434 ? N LYS E 434 
AD1 2 3 O ARG E 437 ? O ARG E 437 N GLU E 398 ? N GLU E 398 
AD1 3 4 N ALA E 397 ? N ALA E 397 O GLY E 466 ? O GLY E 466 
AD2 1 2 N TYR F 117 ? N TYR F 115 O TRP F 213 ? O TRP F 211 
AD2 2 3 O ILE F 214 ? O ILE F 212 N ILE F 193 ? N ILE F 191 
AD2 3 4 N MET F 197 ? N MET F 195 O GLN F 209 ? O GLN F 207 
AD3 1 2 N TYR F 117 ? N TYR F 115 O TRP F 213 ? O TRP F 211 
AD3 2 3 O ILE F 214 ? O ILE F 212 N ILE F 193 ? N ILE F 191 
AD3 3 4 O GLN F 191 ? O GLN F 189 N LYS F 174 ? N LYS F 172 
AD3 4 5 O TRP F 177 ? O TRP F 175 N ARG F 72  ? N ARG F 70  
AD3 5 6 N TYR F 75  ? N TYR F 73  O VAL F 255 ? O VAL F 253 
AD4 1 2 N VAL F 228 ? N VAL F 226 O SER F 239 ? O SER F 237 
# 
_pdbx_entry_details.entry_id                   9MZU 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O4 J MAN 1   ? ? H1 J RAM 5   ? ? 1.50 
2 1 O4 H MAN 1   ? ? H1 H RAM 5   ? ? 1.50 
3 1 O4 L MAN 1   ? ? H1 L RAM 5   ? ? 1.50 
4 1 OG D SER 272 ? ? H1 D MAN 401 ? ? 1.54 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 68  ? ? 73.98   -5.95  
2  1 HIS A 169 ? ? 72.04   36.33  
3  1 PRO A 344 ? ? -77.86  45.30  
4  1 LEU A 374 ? ? -90.90  -60.22 
5  1 ASN A 395 ? ? 66.02   -96.77 
6  1 SER B 82  ? ? 77.77   -4.63  
7  1 GLU B 134 ? ? -90.85  46.05  
8  1 GLU B 203 ? ? 68.48   171.75 
9  1 SER C 68  ? ? 74.06   -6.33  
10 1 TYR C 117 ? ? -94.85  -60.83 
11 1 PRO C 344 ? ? -78.20  45.83  
12 1 LEU C 374 ? ? -91.18  -61.82 
13 1 ASN C 395 ? ? 64.84   -97.26 
14 1 SER D 82  ? ? 75.92   -5.92  
15 1 PHE D 124 ? ? -94.08  58.43  
16 1 GLU D 134 ? ? -91.83  47.68  
17 1 PHE D 135 ? ? -130.14 -39.78 
18 1 ALA D 151 ? ? 55.48   18.95  
19 1 PHE D 201 ? ? 75.45   -7.92  
20 1 GLU D 203 ? ? 66.36   168.66 
21 1 SER E 68  ? ? 74.60   -6.14  
22 1 PRO E 344 ? ? -79.82  44.86  
23 1 ASN E 395 ? ? 69.57   -95.16 
24 1 SER F 82  ? ? 76.78   -4.46  
25 1 PHE F 124 ? ? -94.19  58.80  
26 1 GLU F 134 ? ? -89.86  48.38  
27 1 PHE F 135 ? ? -133.11 -30.81 
28 1 THR F 196 ? ? -119.70 50.51  
29 1 PHE F 201 ? ? 76.27   -7.71  
30 1 GLU F 203 ? ? 68.77   166.21 
# 
_space_group_symop.id              1 
_space_group_symop.operation_xyz   x,y,z 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MZU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9MZU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               676608 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 PorKN 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2 
# 
_em_imaging.entry_id                        9MZU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             100 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_vitrification.entry_id              9MZU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9MZU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A CYS 2   ? A CYS 2   
3   1 Y 1 A ARG 3   ? A ARG 3   
4   1 Y 1 A LYS 4   ? A LYS 4   
5   1 Y 1 A ASN 5   ? A ASN 5   
6   1 Y 1 A ARG 6   ? A ARG 6   
7   1 Y 1 A PHE 7   ? A PHE 7   
8   1 Y 1 A PHE 8   ? A PHE 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A LEU 10  ? A LEU 10  
11  1 Y 1 A ALA 11  ? A ALA 11  
12  1 Y 1 A GLY 12  ? A GLY 12  
13  1 Y 1 A PHE 13  ? A PHE 13  
14  1 Y 1 A PHE 14  ? A PHE 14  
15  1 Y 1 A LEU 15  ? A LEU 15  
16  1 Y 1 A PHE 16  ? A PHE 16  
17  1 Y 1 A GLY 17  ? A GLY 17  
18  1 Y 1 A VAL 18  ? A VAL 18  
19  1 Y 1 A PHE 19  ? A PHE 19  
20  1 Y 1 A THR 20  ? A THR 20  
21  1 Y 1 A ILE 21  ? A ILE 21  
22  1 Y 1 A SER 22  ? A SER 22  
23  1 Y 1 A SER 23  ? A SER 23  
24  1 Y 1 A CYS 24  ? A CYS 24  
25  1 Y 1 A GLY 25  ? A GLY 25  
26  1 Y 1 A SER 26  ? A SER 26  
27  1 Y 1 A SER 27  ? A SER 27  
28  1 Y 1 A LYS 28  ? A LYS 28  
29  1 Y 1 A ARG 29  ? A ARG 29  
30  1 Y 1 A ALA 30  ? A ALA 30  
31  1 Y 1 A VAL 31  ? A VAL 31  
32  1 Y 1 A SER 477 ? A SER 477 
33  1 Y 1 A SER 478 ? A SER 478 
34  1 Y 1 A GLY 479 ? A GLY 479 
35  1 Y 1 A LYS 480 ? A LYS 480 
36  1 Y 1 A ALA 481 ? A ALA 481 
37  1 Y 1 A PRO 482 ? A PRO 482 
38  1 Y 1 A LYS 483 ? A LYS 483 
39  1 Y 1 A SER 484 ? A SER 484 
40  1 Y 1 A SER 485 ? A SER 485 
41  1 Y 1 A ARG 486 ? A ARG 486 
42  1 Y 1 A ARG 487 ? A ARG 487 
43  1 Y 1 A SER 488 ? A SER 488 
44  1 Y 1 A THR 489 ? A THR 489 
45  1 Y 1 A LYS 490 ? A LYS 490 
46  1 Y 1 A LYS 491 ? A LYS 491 
47  1 Y 1 B MET -1  ? B MET 1   
48  1 Y 1 B PHE 0   ? B PHE 2   
49  1 Y 1 B MET 1   ? B MET 3   
50  1 Y 1 B LYS 2   ? B LYS 4   
51  1 Y 1 B VAL 3   ? B VAL 5   
52  1 Y 1 B PHE 4   ? B PHE 6   
53  1 Y 1 B LYS 5   ? B LYS 7   
54  1 Y 1 B ALA 6   ? B ALA 8   
55  1 Y 1 B VAL 7   ? B VAL 9   
56  1 Y 1 B ILE 8   ? B ILE 10  
57  1 Y 1 B GLY 9   ? B GLY 11  
58  1 Y 1 B ALA 10  ? B ALA 12  
59  1 Y 1 B ILE 11  ? B ILE 13  
60  1 Y 1 B LEU 12  ? B LEU 14  
61  1 Y 1 B ALA 13  ? B ALA 15  
62  1 Y 1 B ALA 14  ? B ALA 16  
63  1 Y 1 B THR 15  ? B THR 17  
64  1 Y 1 B VAL 16  ? B VAL 18  
65  1 Y 1 B SER 17  ? B SER 19  
66  1 Y 1 B ILE 18  ? B ILE 20  
67  1 Y 1 B SER 19  ? B SER 21  
68  1 Y 1 B SER 20  ? B SER 22  
69  1 Y 1 B VAL 21  ? B VAL 23  
70  1 Y 1 B ALA 22  ? B ALA 24  
71  1 Y 1 B GLN 23  ? B GLN 25  
72  1 Y 1 B GLU 24  ? B GLU 26  
73  1 Y 1 B ASN 25  ? B ASN 27  
74  1 Y 1 B THR 26  ? B THR 28  
75  1 Y 1 B ASN 27  ? B ASN 29  
76  1 Y 1 B ASN 28  ? B ASN 30  
77  1 Y 1 B ARG 29  ? B ARG 31  
78  1 Y 1 B SER 30  ? B SER 32  
79  1 Y 1 B PRO 31  ? B PRO 33  
80  1 Y 1 B GLN 32  ? B GLN 34  
81  1 Y 1 B VAL 33  ? B VAL 35  
82  1 Y 1 B GLY 34  ? B GLY 36  
83  1 Y 1 B ARG 35  ? B ARG 37  
84  1 Y 1 B ALA 36  ? B ALA 38  
85  1 Y 1 B PRO 37  ? B PRO 39  
86  1 Y 1 B ARG 38  ? B ARG 40  
87  1 Y 1 B ASN 39  ? B ASN 41  
88  1 Y 1 B THR 40  ? B THR 42  
89  1 Y 1 B GLU 41  ? B GLU 43  
90  1 Y 1 B VAL 42  ? B VAL 44  
91  1 Y 1 B GLU 43  ? B GLU 45  
92  1 Y 1 B GLN 44  ? B GLN 46  
93  1 Y 1 B THR 45  ? B THR 47  
94  1 Y 1 B THR 46  ? B THR 48  
95  1 Y 1 B MET 300 ? B MET 302 
96  1 Y 1 B LYS 301 ? B LYS 303 
97  1 Y 1 B GLN 302 ? B GLN 304 
98  1 Y 1 B ALA 303 ? B ALA 305 
99  1 Y 1 B GLU 304 ? B GLU 306 
100 1 Y 1 B THR 305 ? B THR 307 
101 1 Y 1 B LYS 306 ? B LYS 308 
102 1 Y 1 B LYS 307 ? B LYS 309 
103 1 Y 1 B SER 308 ? B SER 310 
104 1 Y 1 B LYS 309 ? B LYS 311 
105 1 Y 1 B GLY 310 ? B GLY 312 
106 1 Y 1 B LYS 311 ? B LYS 313 
107 1 Y 1 B LYS 312 ? B LYS 314 
108 1 Y 1 B LEU 313 ? B LEU 315 
109 1 Y 1 B GLU 314 ? B GLU 316 
110 1 Y 1 B LYS 315 ? B LYS 317 
111 1 Y 1 B ALA 316 ? B ALA 318 
112 1 Y 1 B ARG 317 ? B ARG 319 
113 1 Y 1 B GLY 318 ? B GLY 320 
114 1 Y 1 B LYS 319 ? B LYS 321 
115 1 Y 1 B ASN 320 ? B ASN 322 
116 1 Y 1 B ILE 321 ? B ILE 323 
117 1 Y 1 B THR 322 ? B THR 324 
118 1 Y 1 B SER 323 ? B SER 325 
119 1 Y 1 B ARG 324 ? B ARG 326 
120 1 Y 1 B THR 325 ? B THR 327 
121 1 Y 1 B ARG 326 ? B ARG 328 
122 1 Y 1 B GLY 327 ? B GLY 329 
123 1 Y 1 B GLN 328 ? B GLN 330 
124 1 Y 1 B GLY 329 ? B GLY 331 
125 1 Y 1 B GLU 330 ? B GLU 332 
126 1 Y 1 B GLY 331 ? B GLY 333 
127 1 Y 1 B ALA 332 ? B ALA 334 
128 1 Y 1 B ALA 333 ? B ALA 335 
129 1 Y 1 B GLU 334 ? B GLU 336 
130 1 Y 1 B THR 335 ? B THR 337 
131 1 Y 1 B GLU 336 ? B GLU 338 
132 1 Y 1 B ALA 337 ? B ALA 339 
133 1 Y 1 B VAL 338 ? B VAL 340 
134 1 Y 1 B GLU 339 ? B GLU 341 
135 1 Y 1 B PRO 340 ? B PRO 342 
136 1 Y 1 B LYS 341 ? B LYS 343 
137 1 Y 1 B LYS 342 ? B LYS 344 
138 1 Y 1 B GLN 343 ? B GLN 345 
139 1 Y 1 B LYS 344 ? B LYS 346 
140 1 Y 1 B ALA 345 ? B ALA 347 
141 1 Y 1 B SER 346 ? B SER 348 
142 1 Y 1 B LYS 347 ? B LYS 349 
143 1 Y 1 B ASN 348 ? B ASN 350 
144 1 Y 1 B LYS 349 ? B LYS 351 
145 1 Y 1 B ALA 350 ? B ALA 352 
146 1 Y 1 B ALA 351 ? B ALA 353 
147 1 Y 1 B THR 352 ? B THR 354 
148 1 Y 1 B ARG 353 ? B ARG 355 
149 1 Y 1 B SER 354 ? B SER 356 
150 1 Y 1 B VAL 355 ? B VAL 357 
151 1 Y 1 B ARG 356 ? B ARG 358 
152 1 Y 1 B ARG 357 ? B ARG 359 
153 1 Y 1 B ARG 358 ? B ARG 360 
154 1 Y 1 B LYS 359 ? B LYS 361 
155 1 Y 1 C MET 1   ? C MET 1   
156 1 Y 1 C CYS 2   ? C CYS 2   
157 1 Y 1 C ARG 3   ? C ARG 3   
158 1 Y 1 C LYS 4   ? C LYS 4   
159 1 Y 1 C ASN 5   ? C ASN 5   
160 1 Y 1 C ARG 6   ? C ARG 6   
161 1 Y 1 C PHE 7   ? C PHE 7   
162 1 Y 1 C PHE 8   ? C PHE 8   
163 1 Y 1 C ALA 9   ? C ALA 9   
164 1 Y 1 C LEU 10  ? C LEU 10  
165 1 Y 1 C ALA 11  ? C ALA 11  
166 1 Y 1 C GLY 12  ? C GLY 12  
167 1 Y 1 C PHE 13  ? C PHE 13  
168 1 Y 1 C PHE 14  ? C PHE 14  
169 1 Y 1 C LEU 15  ? C LEU 15  
170 1 Y 1 C PHE 16  ? C PHE 16  
171 1 Y 1 C GLY 17  ? C GLY 17  
172 1 Y 1 C VAL 18  ? C VAL 18  
173 1 Y 1 C PHE 19  ? C PHE 19  
174 1 Y 1 C THR 20  ? C THR 20  
175 1 Y 1 C ILE 21  ? C ILE 21  
176 1 Y 1 C SER 22  ? C SER 22  
177 1 Y 1 C SER 23  ? C SER 23  
178 1 Y 1 C CYS 24  ? C CYS 24  
179 1 Y 1 C GLY 25  ? C GLY 25  
180 1 Y 1 C SER 26  ? C SER 26  
181 1 Y 1 C SER 27  ? C SER 27  
182 1 Y 1 C LYS 28  ? C LYS 28  
183 1 Y 1 C ARG 29  ? C ARG 29  
184 1 Y 1 C ALA 30  ? C ALA 30  
185 1 Y 1 C VAL 31  ? C VAL 31  
186 1 Y 1 C SER 477 ? C SER 477 
187 1 Y 1 C SER 478 ? C SER 478 
188 1 Y 1 C GLY 479 ? C GLY 479 
189 1 Y 1 C LYS 480 ? C LYS 480 
190 1 Y 1 C ALA 481 ? C ALA 481 
191 1 Y 1 C PRO 482 ? C PRO 482 
192 1 Y 1 C LYS 483 ? C LYS 483 
193 1 Y 1 C SER 484 ? C SER 484 
194 1 Y 1 C SER 485 ? C SER 485 
195 1 Y 1 C ARG 486 ? C ARG 486 
196 1 Y 1 C ARG 487 ? C ARG 487 
197 1 Y 1 C SER 488 ? C SER 488 
198 1 Y 1 C THR 489 ? C THR 489 
199 1 Y 1 C LYS 490 ? C LYS 490 
200 1 Y 1 C LYS 491 ? C LYS 491 
201 1 Y 1 D MET -1  ? D MET 1   
202 1 Y 1 D PHE 0   ? D PHE 2   
203 1 Y 1 D MET 1   ? D MET 3   
204 1 Y 1 D LYS 2   ? D LYS 4   
205 1 Y 1 D VAL 3   ? D VAL 5   
206 1 Y 1 D PHE 4   ? D PHE 6   
207 1 Y 1 D LYS 5   ? D LYS 7   
208 1 Y 1 D ALA 6   ? D ALA 8   
209 1 Y 1 D VAL 7   ? D VAL 9   
210 1 Y 1 D ILE 8   ? D ILE 10  
211 1 Y 1 D GLY 9   ? D GLY 11  
212 1 Y 1 D ALA 10  ? D ALA 12  
213 1 Y 1 D ILE 11  ? D ILE 13  
214 1 Y 1 D LEU 12  ? D LEU 14  
215 1 Y 1 D ALA 13  ? D ALA 15  
216 1 Y 1 D ALA 14  ? D ALA 16  
217 1 Y 1 D THR 15  ? D THR 17  
218 1 Y 1 D VAL 16  ? D VAL 18  
219 1 Y 1 D SER 17  ? D SER 19  
220 1 Y 1 D ILE 18  ? D ILE 20  
221 1 Y 1 D SER 19  ? D SER 21  
222 1 Y 1 D SER 20  ? D SER 22  
223 1 Y 1 D VAL 21  ? D VAL 23  
224 1 Y 1 D ALA 22  ? D ALA 24  
225 1 Y 1 D GLN 23  ? D GLN 25  
226 1 Y 1 D GLU 24  ? D GLU 26  
227 1 Y 1 D ASN 25  ? D ASN 27  
228 1 Y 1 D THR 26  ? D THR 28  
229 1 Y 1 D ASN 27  ? D ASN 29  
230 1 Y 1 D ASN 28  ? D ASN 30  
231 1 Y 1 D ARG 29  ? D ARG 31  
232 1 Y 1 D SER 30  ? D SER 32  
233 1 Y 1 D PRO 31  ? D PRO 33  
234 1 Y 1 D GLN 32  ? D GLN 34  
235 1 Y 1 D VAL 33  ? D VAL 35  
236 1 Y 1 D GLY 34  ? D GLY 36  
237 1 Y 1 D ARG 35  ? D ARG 37  
238 1 Y 1 D ALA 36  ? D ALA 38  
239 1 Y 1 D PRO 37  ? D PRO 39  
240 1 Y 1 D ARG 38  ? D ARG 40  
241 1 Y 1 D ASN 39  ? D ASN 41  
242 1 Y 1 D THR 40  ? D THR 42  
243 1 Y 1 D GLU 41  ? D GLU 43  
244 1 Y 1 D VAL 42  ? D VAL 44  
245 1 Y 1 D GLU 43  ? D GLU 45  
246 1 Y 1 D GLN 44  ? D GLN 46  
247 1 Y 1 D THR 45  ? D THR 47  
248 1 Y 1 D THR 46  ? D THR 48  
249 1 Y 1 D MET 300 ? D MET 302 
250 1 Y 1 D LYS 301 ? D LYS 303 
251 1 Y 1 D GLN 302 ? D GLN 304 
252 1 Y 1 D ALA 303 ? D ALA 305 
253 1 Y 1 D GLU 304 ? D GLU 306 
254 1 Y 1 D THR 305 ? D THR 307 
255 1 Y 1 D LYS 306 ? D LYS 308 
256 1 Y 1 D LYS 307 ? D LYS 309 
257 1 Y 1 D SER 308 ? D SER 310 
258 1 Y 1 D LYS 309 ? D LYS 311 
259 1 Y 1 D GLY 310 ? D GLY 312 
260 1 Y 1 D LYS 311 ? D LYS 313 
261 1 Y 1 D LYS 312 ? D LYS 314 
262 1 Y 1 D LEU 313 ? D LEU 315 
263 1 Y 1 D GLU 314 ? D GLU 316 
264 1 Y 1 D LYS 315 ? D LYS 317 
265 1 Y 1 D ALA 316 ? D ALA 318 
266 1 Y 1 D ARG 317 ? D ARG 319 
267 1 Y 1 D GLY 318 ? D GLY 320 
268 1 Y 1 D LYS 319 ? D LYS 321 
269 1 Y 1 D ASN 320 ? D ASN 322 
270 1 Y 1 D ILE 321 ? D ILE 323 
271 1 Y 1 D THR 322 ? D THR 324 
272 1 Y 1 D SER 323 ? D SER 325 
273 1 Y 1 D ARG 324 ? D ARG 326 
274 1 Y 1 D THR 325 ? D THR 327 
275 1 Y 1 D ARG 326 ? D ARG 328 
276 1 Y 1 D GLY 327 ? D GLY 329 
277 1 Y 1 D GLN 328 ? D GLN 330 
278 1 Y 1 D GLY 329 ? D GLY 331 
279 1 Y 1 D GLU 330 ? D GLU 332 
280 1 Y 1 D GLY 331 ? D GLY 333 
281 1 Y 1 D ALA 332 ? D ALA 334 
282 1 Y 1 D ALA 333 ? D ALA 335 
283 1 Y 1 D GLU 334 ? D GLU 336 
284 1 Y 1 D THR 335 ? D THR 337 
285 1 Y 1 D GLU 336 ? D GLU 338 
286 1 Y 1 D ALA 337 ? D ALA 339 
287 1 Y 1 D VAL 338 ? D VAL 340 
288 1 Y 1 D GLU 339 ? D GLU 341 
289 1 Y 1 D PRO 340 ? D PRO 342 
290 1 Y 1 D LYS 341 ? D LYS 343 
291 1 Y 1 D LYS 342 ? D LYS 344 
292 1 Y 1 D GLN 343 ? D GLN 345 
293 1 Y 1 D LYS 344 ? D LYS 346 
294 1 Y 1 D ALA 345 ? D ALA 347 
295 1 Y 1 D SER 346 ? D SER 348 
296 1 Y 1 D LYS 347 ? D LYS 349 
297 1 Y 1 D ASN 348 ? D ASN 350 
298 1 Y 1 D LYS 349 ? D LYS 351 
299 1 Y 1 D ALA 350 ? D ALA 352 
300 1 Y 1 D ALA 351 ? D ALA 353 
301 1 Y 1 D THR 352 ? D THR 354 
302 1 Y 1 D ARG 353 ? D ARG 355 
303 1 Y 1 D SER 354 ? D SER 356 
304 1 Y 1 D VAL 355 ? D VAL 357 
305 1 Y 1 D ARG 356 ? D ARG 358 
306 1 Y 1 D ARG 357 ? D ARG 359 
307 1 Y 1 D ARG 358 ? D ARG 360 
308 1 Y 1 D LYS 359 ? D LYS 361 
309 1 Y 1 E MET 1   ? E MET 1   
310 1 Y 1 E CYS 2   ? E CYS 2   
311 1 Y 1 E ARG 3   ? E ARG 3   
312 1 Y 1 E LYS 4   ? E LYS 4   
313 1 Y 1 E ASN 5   ? E ASN 5   
314 1 Y 1 E ARG 6   ? E ARG 6   
315 1 Y 1 E PHE 7   ? E PHE 7   
316 1 Y 1 E PHE 8   ? E PHE 8   
317 1 Y 1 E ALA 9   ? E ALA 9   
318 1 Y 1 E LEU 10  ? E LEU 10  
319 1 Y 1 E ALA 11  ? E ALA 11  
320 1 Y 1 E GLY 12  ? E GLY 12  
321 1 Y 1 E PHE 13  ? E PHE 13  
322 1 Y 1 E PHE 14  ? E PHE 14  
323 1 Y 1 E LEU 15  ? E LEU 15  
324 1 Y 1 E PHE 16  ? E PHE 16  
325 1 Y 1 E GLY 17  ? E GLY 17  
326 1 Y 1 E VAL 18  ? E VAL 18  
327 1 Y 1 E PHE 19  ? E PHE 19  
328 1 Y 1 E THR 20  ? E THR 20  
329 1 Y 1 E ILE 21  ? E ILE 21  
330 1 Y 1 E SER 22  ? E SER 22  
331 1 Y 1 E SER 23  ? E SER 23  
332 1 Y 1 E CYS 24  ? E CYS 24  
333 1 Y 1 E GLY 25  ? E GLY 25  
334 1 Y 1 E SER 26  ? E SER 26  
335 1 Y 1 E SER 27  ? E SER 27  
336 1 Y 1 E LYS 28  ? E LYS 28  
337 1 Y 1 E ARG 29  ? E ARG 29  
338 1 Y 1 E ALA 30  ? E ALA 30  
339 1 Y 1 E VAL 31  ? E VAL 31  
340 1 Y 1 E SER 477 ? E SER 477 
341 1 Y 1 E SER 478 ? E SER 478 
342 1 Y 1 E GLY 479 ? E GLY 479 
343 1 Y 1 E LYS 480 ? E LYS 480 
344 1 Y 1 E ALA 481 ? E ALA 481 
345 1 Y 1 E PRO 482 ? E PRO 482 
346 1 Y 1 E LYS 483 ? E LYS 483 
347 1 Y 1 E SER 484 ? E SER 484 
348 1 Y 1 E SER 485 ? E SER 485 
349 1 Y 1 E ARG 486 ? E ARG 486 
350 1 Y 1 E ARG 487 ? E ARG 487 
351 1 Y 1 E SER 488 ? E SER 488 
352 1 Y 1 E THR 489 ? E THR 489 
353 1 Y 1 E LYS 490 ? E LYS 490 
354 1 Y 1 E LYS 491 ? E LYS 491 
355 1 Y 1 F MET -1  ? F MET 1   
356 1 Y 1 F PHE 0   ? F PHE 2   
357 1 Y 1 F MET 1   ? F MET 3   
358 1 Y 1 F LYS 2   ? F LYS 4   
359 1 Y 1 F VAL 3   ? F VAL 5   
360 1 Y 1 F PHE 4   ? F PHE 6   
361 1 Y 1 F LYS 5   ? F LYS 7   
362 1 Y 1 F ALA 6   ? F ALA 8   
363 1 Y 1 F VAL 7   ? F VAL 9   
364 1 Y 1 F ILE 8   ? F ILE 10  
365 1 Y 1 F GLY 9   ? F GLY 11  
366 1 Y 1 F ALA 10  ? F ALA 12  
367 1 Y 1 F ILE 11  ? F ILE 13  
368 1 Y 1 F LEU 12  ? F LEU 14  
369 1 Y 1 F ALA 13  ? F ALA 15  
370 1 Y 1 F ALA 14  ? F ALA 16  
371 1 Y 1 F THR 15  ? F THR 17  
372 1 Y 1 F VAL 16  ? F VAL 18  
373 1 Y 1 F SER 17  ? F SER 19  
374 1 Y 1 F ILE 18  ? F ILE 20  
375 1 Y 1 F SER 19  ? F SER 21  
376 1 Y 1 F SER 20  ? F SER 22  
377 1 Y 1 F VAL 21  ? F VAL 23  
378 1 Y 1 F ALA 22  ? F ALA 24  
379 1 Y 1 F GLN 23  ? F GLN 25  
380 1 Y 1 F GLU 24  ? F GLU 26  
381 1 Y 1 F ASN 25  ? F ASN 27  
382 1 Y 1 F THR 26  ? F THR 28  
383 1 Y 1 F ASN 27  ? F ASN 29  
384 1 Y 1 F ASN 28  ? F ASN 30  
385 1 Y 1 F ARG 29  ? F ARG 31  
386 1 Y 1 F SER 30  ? F SER 32  
387 1 Y 1 F PRO 31  ? F PRO 33  
388 1 Y 1 F GLN 32  ? F GLN 34  
389 1 Y 1 F VAL 33  ? F VAL 35  
390 1 Y 1 F GLY 34  ? F GLY 36  
391 1 Y 1 F ARG 35  ? F ARG 37  
392 1 Y 1 F ALA 36  ? F ALA 38  
393 1 Y 1 F PRO 37  ? F PRO 39  
394 1 Y 1 F ARG 38  ? F ARG 40  
395 1 Y 1 F ASN 39  ? F ASN 41  
396 1 Y 1 F THR 40  ? F THR 42  
397 1 Y 1 F GLU 41  ? F GLU 43  
398 1 Y 1 F VAL 42  ? F VAL 44  
399 1 Y 1 F GLU 43  ? F GLU 45  
400 1 Y 1 F GLN 44  ? F GLN 46  
401 1 Y 1 F THR 45  ? F THR 47  
402 1 Y 1 F THR 46  ? F THR 48  
403 1 Y 1 F MET 300 ? F MET 302 
404 1 Y 1 F LYS 301 ? F LYS 303 
405 1 Y 1 F GLN 302 ? F GLN 304 
406 1 Y 1 F ALA 303 ? F ALA 305 
407 1 Y 1 F GLU 304 ? F GLU 306 
408 1 Y 1 F THR 305 ? F THR 307 
409 1 Y 1 F LYS 306 ? F LYS 308 
410 1 Y 1 F LYS 307 ? F LYS 309 
411 1 Y 1 F SER 308 ? F SER 310 
412 1 Y 1 F LYS 309 ? F LYS 311 
413 1 Y 1 F GLY 310 ? F GLY 312 
414 1 Y 1 F LYS 311 ? F LYS 313 
415 1 Y 1 F LYS 312 ? F LYS 314 
416 1 Y 1 F LEU 313 ? F LEU 315 
417 1 Y 1 F GLU 314 ? F GLU 316 
418 1 Y 1 F LYS 315 ? F LYS 317 
419 1 Y 1 F ALA 316 ? F ALA 318 
420 1 Y 1 F ARG 317 ? F ARG 319 
421 1 Y 1 F GLY 318 ? F GLY 320 
422 1 Y 1 F LYS 319 ? F LYS 321 
423 1 Y 1 F ASN 320 ? F ASN 322 
424 1 Y 1 F ILE 321 ? F ILE 323 
425 1 Y 1 F THR 322 ? F THR 324 
426 1 Y 1 F SER 323 ? F SER 325 
427 1 Y 1 F ARG 324 ? F ARG 326 
428 1 Y 1 F THR 325 ? F THR 327 
429 1 Y 1 F ARG 326 ? F ARG 328 
430 1 Y 1 F GLY 327 ? F GLY 329 
431 1 Y 1 F GLN 328 ? F GLN 330 
432 1 Y 1 F GLY 329 ? F GLY 331 
433 1 Y 1 F GLU 330 ? F GLU 332 
434 1 Y 1 F GLY 331 ? F GLY 333 
435 1 Y 1 F ALA 332 ? F ALA 334 
436 1 Y 1 F ALA 333 ? F ALA 335 
437 1 Y 1 F GLU 334 ? F GLU 336 
438 1 Y 1 F THR 335 ? F THR 337 
439 1 Y 1 F GLU 336 ? F GLU 338 
440 1 Y 1 F ALA 337 ? F ALA 339 
441 1 Y 1 F VAL 338 ? F VAL 340 
442 1 Y 1 F GLU 339 ? F GLU 341 
443 1 Y 1 F PRO 340 ? F PRO 342 
444 1 Y 1 F LYS 341 ? F LYS 343 
445 1 Y 1 F LYS 342 ? F LYS 344 
446 1 Y 1 F GLN 343 ? F GLN 345 
447 1 Y 1 F LYS 344 ? F LYS 346 
448 1 Y 1 F ALA 345 ? F ALA 347 
449 1 Y 1 F SER 346 ? F SER 348 
450 1 Y 1 F LYS 347 ? F LYS 349 
451 1 Y 1 F ASN 348 ? F ASN 350 
452 1 Y 1 F LYS 349 ? F LYS 351 
453 1 Y 1 F ALA 350 ? F ALA 352 
454 1 Y 1 F ALA 351 ? F ALA 353 
455 1 Y 1 F THR 352 ? F THR 354 
456 1 Y 1 F ARG 353 ? F ARG 355 
457 1 Y 1 F SER 354 ? F SER 356 
458 1 Y 1 F VAL 355 ? F VAL 357 
459 1 Y 1 F ARG 356 ? F ARG 358 
460 1 Y 1 F ARG 357 ? F ARG 359 
461 1 Y 1 F ARG 358 ? F ARG 360 
462 1 Y 1 F LYS 359 ? F LYS 361 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
FUC C1   C  N R 89  
FUC C2   C  N S 90  
FUC C3   C  N R 91  
FUC C4   C  N S 92  
FUC C5   C  N S 93  
FUC C6   C  N N 94  
FUC O1   O  N N 95  
FUC O2   O  N N 96  
FUC O3   O  N N 97  
FUC O4   O  N N 98  
FUC O5   O  N N 99  
FUC H1   H  N N 100 
FUC H2   H  N N 101 
FUC H3   H  N N 102 
FUC H4   H  N N 103 
FUC H5   H  N N 104 
FUC H61  H  N N 105 
FUC H62  H  N N 106 
FUC H63  H  N N 107 
FUC HO1  H  N N 108 
FUC HO2  H  N N 109 
FUC HO3  H  N N 110 
FUC HO4  H  N N 111 
GCU C1   C  N S 112 
GCU C2   C  N R 113 
GCU C3   C  N S 114 
GCU C4   C  N S 115 
GCU C5   C  N S 116 
GCU C6   C  N N 117 
GCU O1   O  N N 118 
GCU O2   O  N N 119 
GCU O3   O  N N 120 
GCU O4   O  N N 121 
GCU O5   O  N N 122 
GCU O6A  O  N N 123 
GCU O6B  O  N N 124 
GCU H1   H  N N 125 
GCU H2   H  N N 126 
GCU H3   H  N N 127 
GCU H4   H  N N 128 
GCU H5   H  N N 129 
GCU HO1  H  N N 130 
GCU HO2  H  N N 131 
GCU HO3  H  N N 132 
GCU HO4  H  N N 133 
GCU HO6B H  N N 134 
GLC C1   C  N S 135 
GLC C2   C  N R 136 
GLC C3   C  N S 137 
GLC C4   C  N S 138 
GLC C5   C  N R 139 
GLC C6   C  N N 140 
GLC O1   O  N N 141 
GLC O2   O  N N 142 
GLC O3   O  N N 143 
GLC O4   O  N N 144 
GLC O5   O  N N 145 
GLC O6   O  N N 146 
GLC H1   H  N N 147 
GLC H2   H  N N 148 
GLC H3   H  N N 149 
GLC H4   H  N N 150 
GLC H5   H  N N 151 
GLC H61  H  N N 152 
GLC H62  H  N N 153 
GLC HO1  H  N N 154 
GLC HO2  H  N N 155 
GLC HO3  H  N N 156 
GLC HO4  H  N N 157 
GLC HO6  H  N N 158 
GLN N    N  N N 159 
GLN CA   C  N S 160 
GLN C    C  N N 161 
GLN O    O  N N 162 
GLN CB   C  N N 163 
GLN CG   C  N N 164 
GLN CD   C  N N 165 
GLN OE1  O  N N 166 
GLN NE2  N  N N 167 
GLN OXT  O  N N 168 
GLN H    H  N N 169 
GLN H2   H  N N 170 
GLN HA   H  N N 171 
GLN HB2  H  N N 172 
GLN HB3  H  N N 173 
GLN HG2  H  N N 174 
GLN HG3  H  N N 175 
GLN HE21 H  N N 176 
GLN HE22 H  N N 177 
GLN HXT  H  N N 178 
GLU N    N  N N 179 
GLU CA   C  N S 180 
GLU C    C  N N 181 
GLU O    O  N N 182 
GLU CB   C  N N 183 
GLU CG   C  N N 184 
GLU CD   C  N N 185 
GLU OE1  O  N N 186 
GLU OE2  O  N N 187 
GLU OXT  O  N N 188 
GLU H    H  N N 189 
GLU H2   H  N N 190 
GLU HA   H  N N 191 
GLU HB2  H  N N 192 
GLU HB3  H  N N 193 
GLU HG2  H  N N 194 
GLU HG3  H  N N 195 
GLU HE2  H  N N 196 
GLU HXT  H  N N 197 
GLY N    N  N N 198 
GLY CA   C  N N 199 
GLY C    C  N N 200 
GLY O    O  N N 201 
GLY OXT  O  N N 202 
GLY H    H  N N 203 
GLY H2   H  N N 204 
GLY HA2  H  N N 205 
GLY HA3  H  N N 206 
GLY HXT  H  N N 207 
HIS N    N  N N 208 
HIS CA   C  N S 209 
HIS C    C  N N 210 
HIS O    O  N N 211 
HIS CB   C  N N 212 
HIS CG   C  Y N 213 
HIS ND1  N  Y N 214 
HIS CD2  C  Y N 215 
HIS CE1  C  Y N 216 
HIS NE2  N  Y N 217 
HIS OXT  O  N N 218 
HIS H    H  N N 219 
HIS H2   H  N N 220 
HIS HA   H  N N 221 
HIS HB2  H  N N 222 
HIS HB3  H  N N 223 
HIS HD1  H  N N 224 
HIS HD2  H  N N 225 
HIS HE1  H  N N 226 
HIS HE2  H  N N 227 
HIS HXT  H  N N 228 
HOH O    O  N N 229 
HOH H1   H  N N 230 
HOH H2   H  N N 231 
ILE N    N  N N 232 
ILE CA   C  N S 233 
ILE C    C  N N 234 
ILE O    O  N N 235 
ILE CB   C  N S 236 
ILE CG1  C  N N 237 
ILE CG2  C  N N 238 
ILE CD1  C  N N 239 
ILE OXT  O  N N 240 
ILE H    H  N N 241 
ILE H2   H  N N 242 
ILE HA   H  N N 243 
ILE HB   H  N N 244 
ILE HG12 H  N N 245 
ILE HG13 H  N N 246 
ILE HG21 H  N N 247 
ILE HG22 H  N N 248 
ILE HG23 H  N N 249 
ILE HD11 H  N N 250 
ILE HD12 H  N N 251 
ILE HD13 H  N N 252 
ILE HXT  H  N N 253 
LEU N    N  N N 254 
LEU CA   C  N S 255 
LEU C    C  N N 256 
LEU O    O  N N 257 
LEU CB   C  N N 258 
LEU CG   C  N N 259 
LEU CD1  C  N N 260 
LEU CD2  C  N N 261 
LEU OXT  O  N N 262 
LEU H    H  N N 263 
LEU H2   H  N N 264 
LEU HA   H  N N 265 
LEU HB2  H  N N 266 
LEU HB3  H  N N 267 
LEU HG   H  N N 268 
LEU HD11 H  N N 269 
LEU HD12 H  N N 270 
LEU HD13 H  N N 271 
LEU HD21 H  N N 272 
LEU HD22 H  N N 273 
LEU HD23 H  N N 274 
LEU HXT  H  N N 275 
LYS N    N  N N 276 
LYS CA   C  N S 277 
LYS C    C  N N 278 
LYS O    O  N N 279 
LYS CB   C  N N 280 
LYS CG   C  N N 281 
LYS CD   C  N N 282 
LYS CE   C  N N 283 
LYS NZ   N  N N 284 
LYS OXT  O  N N 285 
LYS H    H  N N 286 
LYS H2   H  N N 287 
LYS HA   H  N N 288 
LYS HB2  H  N N 289 
LYS HB3  H  N N 290 
LYS HG2  H  N N 291 
LYS HG3  H  N N 292 
LYS HD2  H  N N 293 
LYS HD3  H  N N 294 
LYS HE2  H  N N 295 
LYS HE3  H  N N 296 
LYS HZ1  H  N N 297 
LYS HZ2  H  N N 298 
LYS HZ3  H  N N 299 
LYS HXT  H  N N 300 
MAN C1   C  N S 301 
MAN C2   C  N S 302 
MAN C3   C  N S 303 
MAN C4   C  N S 304 
MAN C5   C  N R 305 
MAN C6   C  N N 306 
MAN O1   O  N N 307 
MAN O2   O  N N 308 
MAN O3   O  N N 309 
MAN O4   O  N N 310 
MAN O5   O  N N 311 
MAN O6   O  N N 312 
MAN H1   H  N N 313 
MAN H2   H  N N 314 
MAN H3   H  N N 315 
MAN H4   H  N N 316 
MAN H5   H  N N 317 
MAN H61  H  N N 318 
MAN H62  H  N N 319 
MAN HO1  H  N N 320 
MAN HO2  H  N N 321 
MAN HO3  H  N N 322 
MAN HO4  H  N N 323 
MAN HO6  H  N N 324 
MET N    N  N N 325 
MET CA   C  N S 326 
MET C    C  N N 327 
MET O    O  N N 328 
MET CB   C  N N 329 
MET CG   C  N N 330 
MET SD   S  N N 331 
MET CE   C  N N 332 
MET OXT  O  N N 333 
MET H    H  N N 334 
MET H2   H  N N 335 
MET HA   H  N N 336 
MET HB2  H  N N 337 
MET HB3  H  N N 338 
MET HG2  H  N N 339 
MET HG3  H  N N 340 
MET HE1  H  N N 341 
MET HE2  H  N N 342 
MET HE3  H  N N 343 
MET HXT  H  N N 344 
PHE N    N  N N 345 
PHE CA   C  N S 346 
PHE C    C  N N 347 
PHE O    O  N N 348 
PHE CB   C  N N 349 
PHE CG   C  Y N 350 
PHE CD1  C  Y N 351 
PHE CD2  C  Y N 352 
PHE CE1  C  Y N 353 
PHE CE2  C  Y N 354 
PHE CZ   C  Y N 355 
PHE OXT  O  N N 356 
PHE H    H  N N 357 
PHE H2   H  N N 358 
PHE HA   H  N N 359 
PHE HB2  H  N N 360 
PHE HB3  H  N N 361 
PHE HD1  H  N N 362 
PHE HD2  H  N N 363 
PHE HE1  H  N N 364 
PHE HE2  H  N N 365 
PHE HZ   H  N N 366 
PHE HXT  H  N N 367 
PRO N    N  N N 368 
PRO CA   C  N S 369 
PRO C    C  N N 370 
PRO O    O  N N 371 
PRO CB   C  N N 372 
PRO CG   C  N N 373 
PRO CD   C  N N 374 
PRO OXT  O  N N 375 
PRO H    H  N N 376 
PRO HA   H  N N 377 
PRO HB2  H  N N 378 
PRO HB3  H  N N 379 
PRO HG2  H  N N 380 
PRO HG3  H  N N 381 
PRO HD2  H  N N 382 
PRO HD3  H  N N 383 
PRO HXT  H  N N 384 
RAM C1   C  N R 385 
RAM C2   C  N R 386 
RAM C3   C  N R 387 
RAM C4   C  N R 388 
RAM C5   C  N S 389 
RAM C6   C  N N 390 
RAM O1   O  N N 391 
RAM O2   O  N N 392 
RAM O3   O  N N 393 
RAM O4   O  N N 394 
RAM O5   O  N N 395 
RAM H1   H  N N 396 
RAM H2   H  N N 397 
RAM H3   H  N N 398 
RAM H4   H  N N 399 
RAM H5   H  N N 400 
RAM H61  H  N N 401 
RAM H62  H  N N 402 
RAM H63  H  N N 403 
RAM HO1  H  N N 404 
RAM HO2  H  N N 405 
RAM HO3  H  N N 406 
RAM HO4  H  N N 407 
SER N    N  N N 408 
SER CA   C  N S 409 
SER C    C  N N 410 
SER O    O  N N 411 
SER CB   C  N N 412 
SER OG   O  N N 413 
SER OXT  O  N N 414 
SER H    H  N N 415 
SER H2   H  N N 416 
SER HA   H  N N 417 
SER HB2  H  N N 418 
SER HB3  H  N N 419 
SER HG   H  N N 420 
SER HXT  H  N N 421 
THR N    N  N N 422 
THR CA   C  N S 423 
THR C    C  N N 424 
THR O    O  N N 425 
THR CB   C  N R 426 
THR OG1  O  N N 427 
THR CG2  C  N N 428 
THR OXT  O  N N 429 
THR H    H  N N 430 
THR H2   H  N N 431 
THR HA   H  N N 432 
THR HB   H  N N 433 
THR HG1  H  N N 434 
THR HG21 H  N N 435 
THR HG22 H  N N 436 
THR HG23 H  N N 437 
THR HXT  H  N N 438 
TRP N    N  N N 439 
TRP CA   C  N S 440 
TRP C    C  N N 441 
TRP O    O  N N 442 
TRP CB   C  N N 443 
TRP CG   C  Y N 444 
TRP CD1  C  Y N 445 
TRP CD2  C  Y N 446 
TRP NE1  N  Y N 447 
TRP CE2  C  Y N 448 
TRP CE3  C  Y N 449 
TRP CZ2  C  Y N 450 
TRP CZ3  C  Y N 451 
TRP CH2  C  Y N 452 
TRP OXT  O  N N 453 
TRP H    H  N N 454 
TRP H2   H  N N 455 
TRP HA   H  N N 456 
TRP HB2  H  N N 457 
TRP HB3  H  N N 458 
TRP HD1  H  N N 459 
TRP HE1  H  N N 460 
TRP HE3  H  N N 461 
TRP HZ2  H  N N 462 
TRP HZ3  H  N N 463 
TRP HH2  H  N N 464 
TRP HXT  H  N N 465 
TYR N    N  N N 466 
TYR CA   C  N S 467 
TYR C    C  N N 468 
TYR O    O  N N 469 
TYR CB   C  N N 470 
TYR CG   C  Y N 471 
TYR CD1  C  Y N 472 
TYR CD2  C  Y N 473 
TYR CE1  C  Y N 474 
TYR CE2  C  Y N 475 
TYR CZ   C  Y N 476 
TYR OH   O  N N 477 
TYR OXT  O  N N 478 
TYR H    H  N N 479 
TYR H2   H  N N 480 
TYR HA   H  N N 481 
TYR HB2  H  N N 482 
TYR HB3  H  N N 483 
TYR HD1  H  N N 484 
TYR HD2  H  N N 485 
TYR HE1  H  N N 486 
TYR HE2  H  N N 487 
TYR HH   H  N N 488 
TYR HXT  H  N N 489 
VAL N    N  N N 490 
VAL CA   C  N S 491 
VAL C    C  N N 492 
VAL O    O  N N 493 
VAL CB   C  N N 494 
VAL CG1  C  N N 495 
VAL CG2  C  N N 496 
VAL OXT  O  N N 497 
VAL H    H  N N 498 
VAL H2   H  N N 499 
VAL HA   H  N N 500 
VAL HB   H  N N 501 
VAL HG11 H  N N 502 
VAL HG12 H  N N 503 
VAL HG13 H  N N 504 
VAL HG21 H  N N 505 
VAL HG22 H  N N 506 
VAL HG23 H  N N 507 
VAL HXT  H  N N 508 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
FUC C1  C2   sing N N 83  
FUC C1  O1   sing N N 84  
FUC C1  O5   sing N N 85  
FUC C1  H1   sing N N 86  
FUC C2  C3   sing N N 87  
FUC C2  O2   sing N N 88  
FUC C2  H2   sing N N 89  
FUC C3  C4   sing N N 90  
FUC C3  O3   sing N N 91  
FUC C3  H3   sing N N 92  
FUC C4  C5   sing N N 93  
FUC C4  O4   sing N N 94  
FUC C4  H4   sing N N 95  
FUC C5  C6   sing N N 96  
FUC C5  O5   sing N N 97  
FUC C5  H5   sing N N 98  
FUC C6  H61  sing N N 99  
FUC C6  H62  sing N N 100 
FUC C6  H63  sing N N 101 
FUC O1  HO1  sing N N 102 
FUC O2  HO2  sing N N 103 
FUC O3  HO3  sing N N 104 
FUC O4  HO4  sing N N 105 
GCU C1  C2   sing N N 106 
GCU C1  O1   sing N N 107 
GCU C1  O5   sing N N 108 
GCU C1  H1   sing N N 109 
GCU C2  C3   sing N N 110 
GCU C2  O2   sing N N 111 
GCU C2  H2   sing N N 112 
GCU C3  C4   sing N N 113 
GCU C3  O3   sing N N 114 
GCU C3  H3   sing N N 115 
GCU C4  C5   sing N N 116 
GCU C4  O4   sing N N 117 
GCU C4  H4   sing N N 118 
GCU C5  C6   sing N N 119 
GCU C5  O5   sing N N 120 
GCU C5  H5   sing N N 121 
GCU C6  O6A  doub N N 122 
GCU C6  O6B  sing N N 123 
GCU O1  HO1  sing N N 124 
GCU O2  HO2  sing N N 125 
GCU O3  HO3  sing N N 126 
GCU O4  HO4  sing N N 127 
GCU O6B HO6B sing N N 128 
GLC C1  C2   sing N N 129 
GLC C1  O1   sing N N 130 
GLC C1  O5   sing N N 131 
GLC C1  H1   sing N N 132 
GLC C2  C3   sing N N 133 
GLC C2  O2   sing N N 134 
GLC C2  H2   sing N N 135 
GLC C3  C4   sing N N 136 
GLC C3  O3   sing N N 137 
GLC C3  H3   sing N N 138 
GLC C4  C5   sing N N 139 
GLC C4  O4   sing N N 140 
GLC C4  H4   sing N N 141 
GLC C5  C6   sing N N 142 
GLC C5  O5   sing N N 143 
GLC C5  H5   sing N N 144 
GLC C6  O6   sing N N 145 
GLC C6  H61  sing N N 146 
GLC C6  H62  sing N N 147 
GLC O1  HO1  sing N N 148 
GLC O2  HO2  sing N N 149 
GLC O3  HO3  sing N N 150 
GLC O4  HO4  sing N N 151 
GLC O6  HO6  sing N N 152 
GLN N   CA   sing N N 153 
GLN N   H    sing N N 154 
GLN N   H2   sing N N 155 
GLN CA  C    sing N N 156 
GLN CA  CB   sing N N 157 
GLN CA  HA   sing N N 158 
GLN C   O    doub N N 159 
GLN C   OXT  sing N N 160 
GLN CB  CG   sing N N 161 
GLN CB  HB2  sing N N 162 
GLN CB  HB3  sing N N 163 
GLN CG  CD   sing N N 164 
GLN CG  HG2  sing N N 165 
GLN CG  HG3  sing N N 166 
GLN CD  OE1  doub N N 167 
GLN CD  NE2  sing N N 168 
GLN NE2 HE21 sing N N 169 
GLN NE2 HE22 sing N N 170 
GLN OXT HXT  sing N N 171 
GLU N   CA   sing N N 172 
GLU N   H    sing N N 173 
GLU N   H2   sing N N 174 
GLU CA  C    sing N N 175 
GLU CA  CB   sing N N 176 
GLU CA  HA   sing N N 177 
GLU C   O    doub N N 178 
GLU C   OXT  sing N N 179 
GLU CB  CG   sing N N 180 
GLU CB  HB2  sing N N 181 
GLU CB  HB3  sing N N 182 
GLU CG  CD   sing N N 183 
GLU CG  HG2  sing N N 184 
GLU CG  HG3  sing N N 185 
GLU CD  OE1  doub N N 186 
GLU CD  OE2  sing N N 187 
GLU OE2 HE2  sing N N 188 
GLU OXT HXT  sing N N 189 
GLY N   CA   sing N N 190 
GLY N   H    sing N N 191 
GLY N   H2   sing N N 192 
GLY CA  C    sing N N 193 
GLY CA  HA2  sing N N 194 
GLY CA  HA3  sing N N 195 
GLY C   O    doub N N 196 
GLY C   OXT  sing N N 197 
GLY OXT HXT  sing N N 198 
HIS N   CA   sing N N 199 
HIS N   H    sing N N 200 
HIS N   H2   sing N N 201 
HIS CA  C    sing N N 202 
HIS CA  CB   sing N N 203 
HIS CA  HA   sing N N 204 
HIS C   O    doub N N 205 
HIS C   OXT  sing N N 206 
HIS CB  CG   sing N N 207 
HIS CB  HB2  sing N N 208 
HIS CB  HB3  sing N N 209 
HIS CG  ND1  sing Y N 210 
HIS CG  CD2  doub Y N 211 
HIS ND1 CE1  doub Y N 212 
HIS ND1 HD1  sing N N 213 
HIS CD2 NE2  sing Y N 214 
HIS CD2 HD2  sing N N 215 
HIS CE1 NE2  sing Y N 216 
HIS CE1 HE1  sing N N 217 
HIS NE2 HE2  sing N N 218 
HIS OXT HXT  sing N N 219 
HOH O   H1   sing N N 220 
HOH O   H2   sing N N 221 
ILE N   CA   sing N N 222 
ILE N   H    sing N N 223 
ILE N   H2   sing N N 224 
ILE CA  C    sing N N 225 
ILE CA  CB   sing N N 226 
ILE CA  HA   sing N N 227 
ILE C   O    doub N N 228 
ILE C   OXT  sing N N 229 
ILE CB  CG1  sing N N 230 
ILE CB  CG2  sing N N 231 
ILE CB  HB   sing N N 232 
ILE CG1 CD1  sing N N 233 
ILE CG1 HG12 sing N N 234 
ILE CG1 HG13 sing N N 235 
ILE CG2 HG21 sing N N 236 
ILE CG2 HG22 sing N N 237 
ILE CG2 HG23 sing N N 238 
ILE CD1 HD11 sing N N 239 
ILE CD1 HD12 sing N N 240 
ILE CD1 HD13 sing N N 241 
ILE OXT HXT  sing N N 242 
LEU N   CA   sing N N 243 
LEU N   H    sing N N 244 
LEU N   H2   sing N N 245 
LEU CA  C    sing N N 246 
LEU CA  CB   sing N N 247 
LEU CA  HA   sing N N 248 
LEU C   O    doub N N 249 
LEU C   OXT  sing N N 250 
LEU CB  CG   sing N N 251 
LEU CB  HB2  sing N N 252 
LEU CB  HB3  sing N N 253 
LEU CG  CD1  sing N N 254 
LEU CG  CD2  sing N N 255 
LEU CG  HG   sing N N 256 
LEU CD1 HD11 sing N N 257 
LEU CD1 HD12 sing N N 258 
LEU CD1 HD13 sing N N 259 
LEU CD2 HD21 sing N N 260 
LEU CD2 HD22 sing N N 261 
LEU CD2 HD23 sing N N 262 
LEU OXT HXT  sing N N 263 
LYS N   CA   sing N N 264 
LYS N   H    sing N N 265 
LYS N   H2   sing N N 266 
LYS CA  C    sing N N 267 
LYS CA  CB   sing N N 268 
LYS CA  HA   sing N N 269 
LYS C   O    doub N N 270 
LYS C   OXT  sing N N 271 
LYS CB  CG   sing N N 272 
LYS CB  HB2  sing N N 273 
LYS CB  HB3  sing N N 274 
LYS CG  CD   sing N N 275 
LYS CG  HG2  sing N N 276 
LYS CG  HG3  sing N N 277 
LYS CD  CE   sing N N 278 
LYS CD  HD2  sing N N 279 
LYS CD  HD3  sing N N 280 
LYS CE  NZ   sing N N 281 
LYS CE  HE2  sing N N 282 
LYS CE  HE3  sing N N 283 
LYS NZ  HZ1  sing N N 284 
LYS NZ  HZ2  sing N N 285 
LYS NZ  HZ3  sing N N 286 
LYS OXT HXT  sing N N 287 
MAN C1  C2   sing N N 288 
MAN C1  O1   sing N N 289 
MAN C1  O5   sing N N 290 
MAN C1  H1   sing N N 291 
MAN C2  C3   sing N N 292 
MAN C2  O2   sing N N 293 
MAN C2  H2   sing N N 294 
MAN C3  C4   sing N N 295 
MAN C3  O3   sing N N 296 
MAN C3  H3   sing N N 297 
MAN C4  C5   sing N N 298 
MAN C4  O4   sing N N 299 
MAN C4  H4   sing N N 300 
MAN C5  C6   sing N N 301 
MAN C5  O5   sing N N 302 
MAN C5  H5   sing N N 303 
MAN C6  O6   sing N N 304 
MAN C6  H61  sing N N 305 
MAN C6  H62  sing N N 306 
MAN O1  HO1  sing N N 307 
MAN O2  HO2  sing N N 308 
MAN O3  HO3  sing N N 309 
MAN O4  HO4  sing N N 310 
MAN O6  HO6  sing N N 311 
MET N   CA   sing N N 312 
MET N   H    sing N N 313 
MET N   H2   sing N N 314 
MET CA  C    sing N N 315 
MET CA  CB   sing N N 316 
MET CA  HA   sing N N 317 
MET C   O    doub N N 318 
MET C   OXT  sing N N 319 
MET CB  CG   sing N N 320 
MET CB  HB2  sing N N 321 
MET CB  HB3  sing N N 322 
MET CG  SD   sing N N 323 
MET CG  HG2  sing N N 324 
MET CG  HG3  sing N N 325 
MET SD  CE   sing N N 326 
MET CE  HE1  sing N N 327 
MET CE  HE2  sing N N 328 
MET CE  HE3  sing N N 329 
MET OXT HXT  sing N N 330 
PHE N   CA   sing N N 331 
PHE N   H    sing N N 332 
PHE N   H2   sing N N 333 
PHE CA  C    sing N N 334 
PHE CA  CB   sing N N 335 
PHE CA  HA   sing N N 336 
PHE C   O    doub N N 337 
PHE C   OXT  sing N N 338 
PHE CB  CG   sing N N 339 
PHE CB  HB2  sing N N 340 
PHE CB  HB3  sing N N 341 
PHE CG  CD1  doub Y N 342 
PHE CG  CD2  sing Y N 343 
PHE CD1 CE1  sing Y N 344 
PHE CD1 HD1  sing N N 345 
PHE CD2 CE2  doub Y N 346 
PHE CD2 HD2  sing N N 347 
PHE CE1 CZ   doub Y N 348 
PHE CE1 HE1  sing N N 349 
PHE CE2 CZ   sing Y N 350 
PHE CE2 HE2  sing N N 351 
PHE CZ  HZ   sing N N 352 
PHE OXT HXT  sing N N 353 
PRO N   CA   sing N N 354 
PRO N   CD   sing N N 355 
PRO N   H    sing N N 356 
PRO CA  C    sing N N 357 
PRO CA  CB   sing N N 358 
PRO CA  HA   sing N N 359 
PRO C   O    doub N N 360 
PRO C   OXT  sing N N 361 
PRO CB  CG   sing N N 362 
PRO CB  HB2  sing N N 363 
PRO CB  HB3  sing N N 364 
PRO CG  CD   sing N N 365 
PRO CG  HG2  sing N N 366 
PRO CG  HG3  sing N N 367 
PRO CD  HD2  sing N N 368 
PRO CD  HD3  sing N N 369 
PRO OXT HXT  sing N N 370 
RAM C1  C2   sing N N 371 
RAM C1  O1   sing N N 372 
RAM C1  O5   sing N N 373 
RAM C1  H1   sing N N 374 
RAM C2  C3   sing N N 375 
RAM C2  O2   sing N N 376 
RAM C2  H2   sing N N 377 
RAM C3  C4   sing N N 378 
RAM C3  O3   sing N N 379 
RAM C3  H3   sing N N 380 
RAM C4  C5   sing N N 381 
RAM C4  O4   sing N N 382 
RAM C4  H4   sing N N 383 
RAM C5  C6   sing N N 384 
RAM C5  O5   sing N N 385 
RAM C5  H5   sing N N 386 
RAM C6  H61  sing N N 387 
RAM C6  H62  sing N N 388 
RAM C6  H63  sing N N 389 
RAM O1  HO1  sing N N 390 
RAM O2  HO2  sing N N 391 
RAM O3  HO3  sing N N 392 
RAM O4  HO4  sing N N 393 
SER N   CA   sing N N 394 
SER N   H    sing N N 395 
SER N   H2   sing N N 396 
SER CA  C    sing N N 397 
SER CA  CB   sing N N 398 
SER CA  HA   sing N N 399 
SER C   O    doub N N 400 
SER C   OXT  sing N N 401 
SER CB  OG   sing N N 402 
SER CB  HB2  sing N N 403 
SER CB  HB3  sing N N 404 
SER OG  HG   sing N N 405 
SER OXT HXT  sing N N 406 
THR N   CA   sing N N 407 
THR N   H    sing N N 408 
THR N   H2   sing N N 409 
THR CA  C    sing N N 410 
THR CA  CB   sing N N 411 
THR CA  HA   sing N N 412 
THR C   O    doub N N 413 
THR C   OXT  sing N N 414 
THR CB  OG1  sing N N 415 
THR CB  CG2  sing N N 416 
THR CB  HB   sing N N 417 
THR OG1 HG1  sing N N 418 
THR CG2 HG21 sing N N 419 
THR CG2 HG22 sing N N 420 
THR CG2 HG23 sing N N 421 
THR OXT HXT  sing N N 422 
TRP N   CA   sing N N 423 
TRP N   H    sing N N 424 
TRP N   H2   sing N N 425 
TRP CA  C    sing N N 426 
TRP CA  CB   sing N N 427 
TRP CA  HA   sing N N 428 
TRP C   O    doub N N 429 
TRP C   OXT  sing N N 430 
TRP CB  CG   sing N N 431 
TRP CB  HB2  sing N N 432 
TRP CB  HB3  sing N N 433 
TRP CG  CD1  doub Y N 434 
TRP CG  CD2  sing Y N 435 
TRP CD1 NE1  sing Y N 436 
TRP CD1 HD1  sing N N 437 
TRP CD2 CE2  doub Y N 438 
TRP CD2 CE3  sing Y N 439 
TRP NE1 CE2  sing Y N 440 
TRP NE1 HE1  sing N N 441 
TRP CE2 CZ2  sing Y N 442 
TRP CE3 CZ3  doub Y N 443 
TRP CE3 HE3  sing N N 444 
TRP CZ2 CH2  doub Y N 445 
TRP CZ2 HZ2  sing N N 446 
TRP CZ3 CH2  sing Y N 447 
TRP CZ3 HZ3  sing N N 448 
TRP CH2 HH2  sing N N 449 
TRP OXT HXT  sing N N 450 
TYR N   CA   sing N N 451 
TYR N   H    sing N N 452 
TYR N   H2   sing N N 453 
TYR CA  C    sing N N 454 
TYR CA  CB   sing N N 455 
TYR CA  HA   sing N N 456 
TYR C   O    doub N N 457 
TYR C   OXT  sing N N 458 
TYR CB  CG   sing N N 459 
TYR CB  HB2  sing N N 460 
TYR CB  HB3  sing N N 461 
TYR CG  CD1  doub Y N 462 
TYR CG  CD2  sing Y N 463 
TYR CD1 CE1  sing Y N 464 
TYR CD1 HD1  sing N N 465 
TYR CD2 CE2  doub Y N 466 
TYR CD2 HD2  sing N N 467 
TYR CE1 CZ   doub Y N 468 
TYR CE1 HE1  sing N N 469 
TYR CE2 CZ   sing Y N 470 
TYR CE2 HE2  sing N N 471 
TYR CZ  OH   sing N N 472 
TYR OH  HH   sing N N 473 
TYR OXT HXT  sing N N 474 
VAL N   CA   sing N N 475 
VAL N   H    sing N N 476 
VAL N   H2   sing N N 477 
VAL CA  C    sing N N 478 
VAL CA  CB   sing N N 479 
VAL CA  HA   sing N N 480 
VAL C   O    doub N N 481 
VAL C   OXT  sing N N 482 
VAL CB  CG1  sing N N 483 
VAL CB  CG2  sing N N 484 
VAL CB  HB   sing N N 485 
VAL CG1 HG11 sing N N 486 
VAL CG1 HG12 sing N N 487 
VAL CG1 HG13 sing N N 488 
VAL CG2 HG21 sing N N 489 
VAL CG2 HG22 sing N N 490 
VAL CG2 HG23 sing N N 491 
VAL OXT HXT  sing N N 492 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-01-23 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MZU 
_em_admin.last_update        2025-04-16 
_em_admin.map_release_date   2025-04-16 
_em_admin.title              'Structure of PorKN from Porphyromonas gingivalis' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          837 
_em_entity_assembly_naturalsource.organism             'Porphyromonas gingivalis' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         55 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'TFS FALCON 4i (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ?        
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX dev_5430 
'IMAGE ACQUISITION'             ? 3  ? ? 1 ?      ?        
MASKING                         ? 4  ? ? ? ?      ?        
'CTF CORRECTION'                ? 5  1 ? ? ?      ?        
'LAYERLINE INDEXING'            ? 6  ? ? ? ?      ?        
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?      ?        
'MODEL FITTING'                 ? 8  ? ? ? ?      ?        
OTHER                           ? 9  ? ? ? ?      ?        
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ?        
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ?        
CLASSIFICATION                  ? 12 1 ? ? ?      ?        
RECONSTRUCTION                  ? 13 1 ? ? ?      ?        
'VOLUME SELECTION'              ? 14 1 1 1 ?      ?        
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ?        
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ?        
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ?        
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ?        
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ?        
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 MAN 1 n 
3 GCU 2 n 
3 GLC 3 n 
3 FUC 4 n 
3 RAM 5 n 
# 
_space_group.crystal_system   triclinic 
_space_group.name_H-M_alt     'P 1' 
_space_group.IT_number        1 
_space_group.name_Hall        'P 1' 
_space_group.id               1 
# 
_atom_sites.entry_id                    9MZU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
H  
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . GLY A 1 32  ? 297.993 230.623 236.815 1.00 62.80  ? 32  GLY A N   1 
ATOM   2     C  CA  . GLY A 1 32  ? 297.189 231.779 237.166 1.00 62.25  ? 32  GLY A CA  1 
ATOM   3     C  C   . GLY A 1 32  ? 297.356 232.937 236.204 1.00 66.54  ? 32  GLY A C   1 
ATOM   4     O  O   . GLY A 1 32  ? 296.721 232.977 235.151 1.00 71.52  ? 32  GLY A O   1 
ATOM   5     N  N   . GLY A 1 33  ? 298.211 233.889 236.570 1.00 62.97  ? 33  GLY A N   1 
ATOM   6     C  CA  . GLY A 1 33  ? 298.473 235.031 235.717 1.00 61.17  ? 33  GLY A CA  1 
ATOM   7     C  C   . GLY A 1 33  ? 298.302 236.371 236.402 1.00 66.51  ? 33  GLY A C   1 
ATOM   8     O  O   . GLY A 1 33  ? 298.525 236.495 237.610 1.00 58.63  ? 33  GLY A O   1 
ATOM   9     N  N   . GLU A 1 34  ? 297.900 237.382 235.636 1.00 68.55  ? 34  GLU A N   1 
ATOM   10    C  CA  . GLU A 1 34  ? 297.792 238.741 236.137 1.00 63.95  ? 34  GLU A CA  1 
ATOM   11    C  C   . GLU A 1 34  ? 296.427 238.969 236.784 1.00 62.38  ? 34  GLU A C   1 
ATOM   12    O  O   . GLU A 1 34  ? 295.553 238.098 236.788 1.00 57.92  ? 34  GLU A O   1 
ATOM   13    C  CB  . GLU A 1 34  ? 298.044 239.742 235.011 1.00 61.71  ? 34  GLU A CB  1 
ATOM   14    C  CG  . GLU A 1 34  ? 299.386 239.566 234.321 1.00 63.91  ? 34  GLU A CG  1 
ATOM   15    C  CD  . GLU A 1 34  ? 300.485 240.390 234.961 1.00 69.84  ? 34  GLU A CD  1 
ATOM   16    O  OE1 . GLU A 1 34  ? 300.283 240.876 236.093 1.00 68.48  ? 34  GLU A OE1 1 
ATOM   17    O  OE2 . GLU A 1 34  ? 301.552 240.552 234.333 1.00 70.25  ? 34  GLU A OE2 1 
ATOM   18    N  N   . LEU A 1 35  ? 296.242 240.167 237.341 1.00 63.30  ? 35  LEU A N   1 
ATOM   19    C  CA  . LEU A 1 35  ? 295.028 240.506 238.081 1.00 57.20  ? 35  LEU A CA  1 
ATOM   20    C  C   . LEU A 1 35  ? 294.017 241.152 237.137 1.00 56.63  ? 35  LEU A C   1 
ATOM   21    O  O   . LEU A 1 35  ? 293.897 242.375 237.034 1.00 52.22  ? 35  LEU A O   1 
ATOM   22    C  CB  . LEU A 1 35  ? 295.353 241.416 239.258 1.00 47.24  ? 35  LEU A CB  1 
ATOM   23    C  CG  . LEU A 1 35  ? 294.137 241.946 240.021 1.00 40.56  ? 35  LEU A CG  1 
ATOM   24    C  CD1 . LEU A 1 35  ? 293.534 240.857 240.890 1.00 37.32  ? 35  LEU A CD1 1 
ATOM   25    C  CD2 . LEU A 1 35  ? 294.505 243.163 240.854 1.00 40.62  ? 35  LEU A CD2 1 
ATOM   26    N  N   . THR A 1 36  ? 293.278 240.302 236.433 1.00 58.00  ? 36  THR A N   1 
ATOM   27    C  CA  . THR A 1 36  ? 292.110 240.748 235.688 1.00 58.38  ? 36  THR A CA  1 
ATOM   28    C  C   . THR A 1 36  ? 290.943 240.873 236.667 1.00 56.67  ? 36  THR A C   1 
ATOM   29    O  O   . THR A 1 36  ? 291.120 240.831 237.887 1.00 54.54  ? 36  THR A O   1 
ATOM   30    C  CB  . THR A 1 36  ? 291.818 239.796 234.531 1.00 58.94  ? 36  THR A CB  1 
ATOM   31    O  OG1 . THR A 1 36  ? 291.306 238.559 235.041 1.00 60.39  ? 36  THR A OG1 1 
ATOM   32    C  CG2 . THR A 1 36  ? 293.087 239.522 233.740 1.00 58.15  ? 36  THR A CG2 1 
ATOM   33    N  N   . GLY A 1 37  ? 289.731 241.040 236.152 1.00 51.03  ? 37  GLY A N   1 
ATOM   34    C  CA  . GLY A 1 37  ? 288.559 241.205 236.987 1.00 41.55  ? 37  GLY A CA  1 
ATOM   35    C  C   . GLY A 1 37  ? 287.591 240.050 236.829 1.00 49.82  ? 37  GLY A C   1 
ATOM   36    O  O   . GLY A 1 37  ? 287.529 239.408 235.780 1.00 52.63  ? 37  GLY A O   1 
ATOM   37    N  N   . ALA A 1 38  ? 286.834 239.785 237.894 1.00 44.89  ? 38  ALA A N   1 
ATOM   38    C  CA  . ALA A 1 38  ? 285.746 238.811 237.858 1.00 41.81  ? 38  ALA A CA  1 
ATOM   39    C  C   . ALA A 1 38  ? 284.440 239.591 237.743 1.00 45.66  ? 38  ALA A C   1 
ATOM   40    O  O   . ALA A 1 38  ? 283.726 239.824 238.718 1.00 45.87  ? 38  ALA A O   1 
ATOM   41    C  CB  . ALA A 1 38  ? 285.777 237.915 239.091 1.00 38.76  ? 38  ALA A CB  1 
ATOM   42    N  N   . LYS A 1 39  ? 284.131 239.996 236.515 1.00 48.12  ? 39  LYS A N   1 
ATOM   43    C  CA  . LYS A 1 39  ? 282.974 240.843 236.270 1.00 49.38  ? 39  LYS A CA  1 
ATOM   44    C  C   . LYS A 1 39  ? 281.675 240.082 236.503 1.00 54.41  ? 39  LYS A C   1 
ATOM   45    O  O   . LYS A 1 39  ? 281.614 238.854 236.393 1.00 56.81  ? 39  LYS A O   1 
ATOM   46    C  CB  . LYS A 1 39  ? 283.005 241.385 234.842 1.00 55.06  ? 39  LYS A CB  1 
ATOM   47    C  CG  . LYS A 1 39  ? 283.969 242.539 234.633 1.00 56.26  ? 39  LYS A CG  1 
ATOM   48    C  CD  . LYS A 1 39  ? 284.116 242.867 233.158 1.00 64.71  ? 39  LYS A CD  1 
ATOM   49    C  CE  . LYS A 1 39  ? 284.945 244.124 232.951 1.00 74.42  ? 39  LYS A CE  1 
ATOM   50    N  NZ  . LYS A 1 39  ? 284.113 245.265 232.480 1.00 79.37  ? 39  LYS A NZ  1 
ATOM   51    N  N   . LEU A 1 40  ? 280.629 240.830 236.832 1.00 55.50  ? 40  LEU A N   1 
ATOM   52    C  CA  . LEU A 1 40  ? 279.294 240.278 236.980 1.00 54.94  ? 40  LEU A CA  1 
ATOM   53    C  C   . LEU A 1 40  ? 278.529 240.392 235.663 1.00 61.11  ? 40  LEU A C   1 
ATOM   54    O  O   . LEU A 1 40  ? 278.933 241.098 234.736 1.00 59.95  ? 40  LEU A O   1 
ATOM   55    C  CB  . LEU A 1 40  ? 278.543 240.992 238.104 1.00 50.31  ? 40  LEU A CB  1 
ATOM   56    C  CG  . LEU A 1 40  ? 279.017 240.710 239.530 1.00 43.56  ? 40  LEU A CG  1 
ATOM   57    C  CD1 . LEU A 1 40  ? 278.186 241.488 240.535 1.00 37.49  ? 40  LEU A CD1 1 
ATOM   58    C  CD2 . LEU A 1 40  ? 278.961 239.222 239.829 1.00 43.34  ? 40  LEU A CD2 1 
ATOM   59    N  N   . SER A 1 41  ? 277.409 239.680 235.586 1.00 66.65  ? 41  SER A N   1 
ATOM   60    C  CA  . SER A 1 41  ? 276.566 239.721 234.398 1.00 71.33  ? 41  SER A CA  1 
ATOM   61    C  C   . SER A 1 41  ? 275.713 240.983 234.412 1.00 74.72  ? 41  SER A C   1 
ATOM   62    O  O   . SER A 1 41  ? 275.044 241.279 235.406 1.00 76.43  ? 41  SER A O   1 
ATOM   63    C  CB  . SER A 1 41  ? 275.681 238.478 234.329 1.00 76.44  ? 41  SER A CB  1 
ATOM   64    O  OG  . SER A 1 41  ? 275.103 238.194 235.591 1.00 81.98  ? 41  SER A OG  1 
ATOM   65    N  N   . SER A 1 42  ? 275.727 241.718 233.303 1.00 78.56  ? 42  SER A N   1 
ATOM   66    C  CA  . SER A 1 42  ? 275.056 243.009 233.250 1.00 78.08  ? 42  SER A CA  1 
ATOM   67    C  C   . SER A 1 42  ? 273.556 242.854 233.471 1.00 78.87  ? 42  SER A C   1 
ATOM   68    O  O   . SER A 1 42  ? 272.943 241.859 233.076 1.00 81.68  ? 42  SER A O   1 
ATOM   69    C  CB  . SER A 1 42  ? 275.316 243.691 231.907 1.00 78.73  ? 42  SER A CB  1 
ATOM   70    O  OG  . SER A 1 42  ? 274.906 242.868 230.831 1.00 78.44  ? 42  SER A OG  1 
ATOM   71    N  N   . TRP A 1 43  ? 272.966 243.857 234.114 1.00 77.46  ? 43  TRP A N   1 
ATOM   72    C  CA  . TRP A 1 43  ? 271.543 243.888 234.408 1.00 84.96  ? 43  TRP A CA  1 
ATOM   73    C  C   . TRP A 1 43  ? 270.844 244.924 233.537 1.00 90.38  ? 43  TRP A C   1 
ATOM   74    O  O   . TRP A 1 43  ? 271.475 245.810 232.953 1.00 91.56  ? 43  TRP A O   1 
ATOM   75    C  CB  . TRP A 1 43  ? 271.296 244.202 235.887 1.00 80.98  ? 43  TRP A CB  1 
ATOM   76    C  CG  . TRP A 1 43  ? 271.854 243.181 236.829 1.00 79.11  ? 43  TRP A CG  1 
ATOM   77    C  CD1 . TRP A 1 43  ? 272.369 241.961 236.505 1.00 79.12  ? 43  TRP A CD1 1 
ATOM   78    C  CD2 . TRP A 1 43  ? 271.953 243.293 238.253 1.00 75.84  ? 43  TRP A CD2 1 
ATOM   79    N  NE1 . TRP A 1 43  ? 272.784 241.306 237.638 1.00 78.82  ? 43  TRP A NE1 1 
ATOM   80    C  CE2 . TRP A 1 43  ? 272.540 242.103 238.725 1.00 78.84  ? 43  TRP A CE2 1 
ATOM   81    C  CE3 . TRP A 1 43  ? 271.604 244.285 239.174 1.00 72.79  ? 43  TRP A CE3 1 
ATOM   82    C  CZ2 . TRP A 1 43  ? 272.785 241.878 240.077 1.00 75.82  ? 43  TRP A CZ2 1 
ATOM   83    C  CZ3 . TRP A 1 43  ? 271.846 244.058 240.516 1.00 72.00  ? 43  TRP A CZ3 1 
ATOM   84    C  CH2 . TRP A 1 43  ? 272.432 242.865 240.954 1.00 72.08  ? 43  TRP A CH2 1 
ATOM   85    N  N   . ASN A 1 44  ? 269.522 244.803 233.457 1.00 90.55  ? 44  ASN A N   1 
ATOM   86    C  CA  . ASN A 1 44  ? 268.679 245.732 232.716 1.00 93.89  ? 44  ASN A CA  1 
ATOM   87    C  C   . ASN A 1 44  ? 267.813 246.501 233.705 1.00 94.59  ? 44  ASN A C   1 
ATOM   88    O  O   . ASN A 1 44  ? 267.093 245.894 234.505 1.00 94.56  ? 44  ASN A O   1 
ATOM   89    C  CB  . ASN A 1 44  ? 267.812 244.992 231.697 1.00 93.98  ? 44  ASN A CB  1 
ATOM   90    C  CG  . ASN A 1 44  ? 267.059 245.934 230.778 1.00 94.68  ? 44  ASN A CG  1 
ATOM   91    O  OD1 . ASN A 1 44  ? 265.849 245.803 230.594 1.00 102.11 ? 44  ASN A OD1 1 
ATOM   92    N  ND2 . ASN A 1 44  ? 267.772 246.891 230.197 1.00 87.32  ? 44  ASN A ND2 1 
ATOM   93    N  N   . GLU A 1 45  ? 267.880 247.831 233.645 1.00 93.14  ? 45  GLU A N   1 
ATOM   94    C  CA  . GLU A 1 45  ? 267.173 248.676 234.596 1.00 90.50  ? 45  GLU A CA  1 
ATOM   95    C  C   . GLU A 1 45  ? 265.839 249.109 234.015 1.00 90.36  ? 45  GLU A C   1 
ATOM   96    O  O   . GLU A 1 45  ? 265.820 249.845 233.016 1.00 88.20  ? 45  GLU A O   1 
ATOM   97    C  CB  . GLU A 1 45  ? 268.012 249.899 234.949 1.00 90.33  ? 45  GLU A CB  1 
ATOM   98    C  CG  . GLU A 1 45  ? 267.226 251.020 235.608 1.00 88.00  ? 45  GLU A CG  1 
ATOM   99    C  CD  . GLU A 1 45  ? 266.823 250.689 237.031 1.00 89.24  ? 45  GLU A CD  1 
ATOM   100   O  OE1 . GLU A 1 45  ? 267.169 249.587 237.505 1.00 89.58  ? 45  GLU A OE1 1 
ATOM   101   O  OE2 . GLU A 1 45  ? 266.160 251.529 237.674 1.00 81.71  ? 45  GLU A OE2 1 
ATOM   102   N  N   . PRO A 1 46  ? 264.713 248.693 234.590 1.00 90.60  ? 46  PRO A N   1 
ATOM   103   C  CA  . PRO A 1 46  ? 263.415 249.175 234.105 1.00 88.09  ? 46  PRO A CA  1 
ATOM   104   C  C   . PRO A 1 46  ? 263.116 250.576 234.614 1.00 82.13  ? 46  PRO A C   1 
ATOM   105   O  O   . PRO A 1 46  ? 263.392 250.915 235.767 1.00 79.67  ? 46  PRO A O   1 
ATOM   106   C  CB  . PRO A 1 46  ? 262.416 248.155 234.672 1.00 84.49  ? 46  PRO A CB  1 
ATOM   107   C  CG  . PRO A 1 46  ? 263.244 247.071 235.324 1.00 83.53  ? 46  PRO A CG  1 
ATOM   108   C  CD  . PRO A 1 46  ? 264.566 247.680 235.645 1.00 85.13  ? 46  PRO A CD  1 
ATOM   109   N  N   . SER A 1 47  ? 262.544 251.395 233.734 1.00 78.98  ? 47  SER A N   1 
ATOM   110   C  CA  . SER A 1 47  ? 262.147 252.748 234.099 1.00 72.47  ? 47  SER A CA  1 
ATOM   111   C  C   . SER A 1 47  ? 260.694 252.738 234.555 1.00 70.34  ? 47  SER A C   1 
ATOM   112   O  O   . SER A 1 47  ? 259.807 252.435 233.746 1.00 67.66  ? 47  SER A O   1 
ATOM   113   C  CB  . SER A 1 47  ? 262.321 253.696 232.925 1.00 69.08  ? 47  SER A CB  1 
ATOM   114   O  OG  . SER A 1 47  ? 261.494 254.838 233.061 1.00 63.24  ? 47  SER A OG  1 
ATOM   115   N  N   . PRO A 1 48  ? 260.405 253.052 235.817 1.00 66.37  ? 48  PRO A N   1 
ATOM   116   C  CA  . PRO A 1 48  ? 259.025 252.938 236.301 1.00 59.52  ? 48  PRO A CA  1 
ATOM   117   C  C   . PRO A 1 48  ? 258.091 253.888 235.569 1.00 57.88  ? 48  PRO A C   1 
ATOM   118   O  O   . PRO A 1 48  ? 258.452 255.019 235.239 1.00 53.98  ? 48  PRO A O   1 
ATOM   119   C  CB  . PRO A 1 48  ? 259.136 253.289 237.791 1.00 51.71  ? 48  PRO A CB  1 
ATOM   120   C  CG  . PRO A 1 48  ? 260.599 253.252 238.108 1.00 51.00  ? 48  PRO A CG  1 
ATOM   121   C  CD  . PRO A 1 48  ? 261.309 253.591 236.844 1.00 53.98  ? 48  PRO A CD  1 
ATOM   122   N  N   . PHE A 1 49  ? 256.875 253.412 235.320 1.00 56.30  ? 49  PHE A N   1 
ATOM   123   C  CA  . PHE A 1 49  ? 255.868 254.222 234.653 1.00 52.77  ? 49  PHE A CA  1 
ATOM   124   C  C   . PHE A 1 49  ? 255.322 255.286 235.597 1.00 51.91  ? 49  PHE A C   1 
ATOM   125   O  O   . PHE A 1 49  ? 255.023 255.013 236.763 1.00 51.05  ? 49  PHE A O   1 
ATOM   126   C  CB  . PHE A 1 49  ? 254.736 253.331 234.144 1.00 53.24  ? 49  PHE A CB  1 
ATOM   127   C  CG  . PHE A 1 49  ? 253.627 254.085 233.480 1.00 57.78  ? 49  PHE A CG  1 
ATOM   128   C  CD1 . PHE A 1 49  ? 253.793 254.609 232.211 1.00 56.79  ? 49  PHE A CD1 1 
ATOM   129   C  CD2 . PHE A 1 49  ? 252.416 254.266 234.123 1.00 57.65  ? 49  PHE A CD2 1 
ATOM   130   C  CE1 . PHE A 1 49  ? 252.773 255.304 231.599 1.00 60.62  ? 49  PHE A CE1 1 
ATOM   131   C  CE2 . PHE A 1 49  ? 251.393 254.960 233.516 1.00 56.57  ? 49  PHE A CE2 1 
ATOM   132   C  CZ  . PHE A 1 49  ? 251.571 255.480 232.252 1.00 60.78  ? 49  PHE A CZ  1 
ATOM   133   N  N   . GLY A 1 50  ? 255.197 256.509 235.087 1.00 49.54  ? 50  GLY A N   1 
ATOM   134   C  CA  . GLY A 1 50  ? 254.664 257.605 235.869 1.00 41.02  ? 50  GLY A CA  1 
ATOM   135   C  C   . GLY A 1 50  ? 255.633 258.240 236.838 1.00 38.68  ? 50  GLY A C   1 
ATOM   136   O  O   . GLY A 1 50  ? 255.200 258.994 237.716 1.00 35.38  ? 50  GLY A O   1 
ATOM   137   N  N   . MET A 1 51  ? 256.928 257.962 236.713 1.00 38.07  ? 51  MET A N   1 
ATOM   138   C  CA  . MET A 1 51  ? 257.932 258.479 237.629 1.00 31.79  ? 51  MET A CA  1 
ATOM   139   C  C   . MET A 1 51  ? 259.000 259.246 236.862 1.00 32.56  ? 51  MET A C   1 
ATOM   140   O  O   . MET A 1 51  ? 259.325 258.920 235.717 1.00 37.20  ? 51  MET A O   1 
ATOM   141   C  CB  . MET A 1 51  ? 258.583 257.347 238.434 1.00 30.99  ? 51  MET A CB  1 
ATOM   142   C  CG  . MET A 1 51  ? 257.592 256.427 239.129 1.00 33.26  ? 51  MET A CG  1 
ATOM   143   S  SD  . MET A 1 51  ? 258.374 255.312 240.309 1.00 46.86  ? 51  MET A SD  1 
ATOM   144   C  CE  . MET A 1 51  ? 258.368 256.314 241.790 1.00 19.27  ? 51  MET A CE  1 
ATOM   145   N  N   . ILE A 1 52  ? 259.535 260.276 237.506 1.00 30.87  ? 52  ILE A N   1 
ATOM   146   C  CA  . ILE A 1 52  ? 260.656 261.036 236.977 1.00 28.59  ? 52  ILE A CA  1 
ATOM   147   C  C   . ILE A 1 52  ? 261.869 260.788 237.861 1.00 26.17  ? 52  ILE A C   1 
ATOM   148   O  O   . ILE A 1 52  ? 261.758 260.442 239.040 1.00 30.26  ? 52  ILE A O   1 
ATOM   149   C  CB  . ILE A 1 52  ? 260.348 262.545 236.878 1.00 27.88  ? 52  ILE A CB  1 
ATOM   150   C  CG1 . ILE A 1 52  ? 259.831 263.076 238.215 1.00 30.19  ? 52  ILE A CG1 1 
ATOM   151   C  CG2 . ILE A 1 52  ? 259.346 262.813 235.772 1.00 28.21  ? 52  ILE A CG2 1 
ATOM   152   C  CD1 . ILE A 1 52  ? 260.911 263.615 239.116 1.00 28.87  ? 52  ILE A CD1 1 
ATOM   153   N  N   . GLN A 1 53  ? 263.046 260.981 237.279 1.00 28.59  ? 53  GLN A N   1 
ATOM   154   C  CA  . GLN A 1 53  ? 264.300 260.757 237.983 1.00 28.08  ? 53  GLN A CA  1 
ATOM   155   C  C   . GLN A 1 53  ? 264.750 262.038 238.673 1.00 28.13  ? 53  GLN A C   1 
ATOM   156   O  O   . GLN A 1 53  ? 264.793 263.103 238.051 1.00 27.69  ? 53  GLN A O   1 
ATOM   157   C  CB  . GLN A 1 53  ? 265.376 260.271 237.013 1.00 34.86  ? 53  GLN A CB  1 
ATOM   158   C  CG  . GLN A 1 53  ? 266.791 260.429 237.530 1.00 39.48  ? 53  GLN A CG  1 
ATOM   159   C  CD  . GLN A 1 53  ? 267.298 259.180 238.216 1.00 39.40  ? 53  GLN A CD  1 
ATOM   160   O  OE1 . GLN A 1 53  ? 267.652 259.206 239.393 1.00 43.26  ? 53  GLN A OE1 1 
ATOM   161   N  NE2 . GLN A 1 53  ? 267.337 258.075 237.481 1.00 39.33  ? 53  GLN A NE2 1 
ATOM   162   N  N   . VAL A 1 54  ? 265.077 261.931 239.953 1.00 30.00  ? 54  VAL A N   1 
ATOM   163   C  CA  . VAL A 1 54  ? 265.631 263.015 240.756 1.00 27.67  ? 54  VAL A CA  1 
ATOM   164   C  C   . VAL A 1 54  ? 267.113 262.723 240.961 1.00 32.96  ? 54  VAL A C   1 
ATOM   165   O  O   . VAL A 1 54  ? 267.459 261.690 241.555 1.00 32.15  ? 54  VAL A O   1 
ATOM   166   C  CB  . VAL A 1 54  ? 264.907 263.153 242.104 1.00 24.12  ? 54  VAL A CB  1 
ATOM   167   C  CG1 . VAL A 1 54  ? 265.564 264.229 242.948 1.00 24.68  ? 54  VAL A CG1 1 
ATOM   168   C  CG2 . VAL A 1 54  ? 263.433 263.457 241.890 1.00 23.97  ? 54  VAL A CG2 1 
ATOM   169   N  N   . PRO A 1 55  ? 268.011 263.584 240.492 1.00 33.96  ? 55  PRO A N   1 
ATOM   170   C  CA  . PRO A 1 55  ? 269.443 263.296 240.597 1.00 26.42  ? 55  PRO A CA  1 
ATOM   171   C  C   . PRO A 1 55  ? 269.952 263.442 242.022 1.00 25.67  ? 55  PRO A C   1 
ATOM   172   O  O   . PRO A 1 55  ? 269.354 264.109 242.869 1.00 25.83  ? 55  PRO A O   1 
ATOM   173   C  CB  . PRO A 1 55  ? 270.074 264.343 239.677 1.00 27.61  ? 55  PRO A CB  1 
ATOM   174   C  CG  . PRO A 1 55  ? 269.129 265.490 239.749 1.00 25.27  ? 55  PRO A CG  1 
ATOM   175   C  CD  . PRO A 1 55  ? 267.756 264.879 239.840 1.00 26.27  ? 55  PRO A CD  1 
ATOM   176   N  N   . ARG A 1 56  ? 271.087 262.798 242.273 1.00 27.47  ? 56  ARG A N   1 
ATOM   177   C  CA  . ARG A 1 56  ? 271.770 262.950 243.546 1.00 22.90  ? 56  ARG A CA  1 
ATOM   178   C  C   . ARG A 1 56  ? 272.272 264.380 243.707 1.00 22.24  ? 56  ARG A C   1 
ATOM   179   O  O   . ARG A 1 56  ? 272.609 265.058 242.733 1.00 24.63  ? 56  ARG A O   1 
ATOM   180   C  CB  . ARG A 1 56  ? 272.941 261.974 243.641 1.00 25.92  ? 56  ARG A CB  1 
ATOM   181   C  CG  . ARG A 1 56  ? 274.195 262.461 242.939 1.00 26.64  ? 56  ARG A CG  1 
ATOM   182   C  CD  . ARG A 1 56  ? 275.358 261.513 243.154 1.00 29.37  ? 56  ARG A CD  1 
ATOM   183   N  NE  . ARG A 1 56  ? 275.139 260.234 242.493 1.00 36.56  ? 56  ARG A NE  1 
ATOM   184   C  CZ  . ARG A 1 56  ? 275.871 259.774 241.488 1.00 34.87  ? 56  ARG A CZ  1 
ATOM   185   N  NH1 . ARG A 1 56  ? 276.888 260.465 241.001 1.00 32.96  ? 56  ARG A NH1 1 
ATOM   186   N  NH2 . ARG A 1 56  ? 275.574 258.593 240.957 1.00 42.17  ? 56  ARG A NH2 1 
ATOM   187   N  N   . GLY A 1 57  ? 272.320 264.838 244.950 1.00 19.99  ? 57  GLY A N   1 
ATOM   188   C  CA  . GLY A 1 57  ? 272.747 266.199 245.200 1.00 18.83  ? 57  GLY A CA  1 
ATOM   189   C  C   . GLY A 1 57  ? 272.704 266.519 246.675 1.00 21.58  ? 57  GLY A C   1 
ATOM   190   O  O   . GLY A 1 57  ? 272.613 265.629 247.522 1.00 25.10  ? 57  GLY A O   1 
ATOM   191   N  N   . SER A 1 58  ? 272.785 267.813 246.969 1.00 23.22  ? 58  SER A N   1 
ATOM   192   C  CA  . SER A 1 58  ? 272.810 268.302 248.337 1.00 23.00  ? 58  SER A CA  1 
ATOM   193   C  C   . SER A 1 58  ? 271.899 269.512 248.456 1.00 22.36  ? 58  SER A C   1 
ATOM   194   O  O   . SER A 1 58  ? 271.670 270.235 247.483 1.00 29.52  ? 58  SER A O   1 
ATOM   195   C  CB  . SER A 1 58  ? 274.235 268.665 248.776 1.00 25.64  ? 58  SER A CB  1 
ATOM   196   O  OG  . SER A 1 58  ? 274.223 269.443 249.959 1.00 32.06  ? 58  SER A OG  1 
ATOM   197   N  N   . ILE A 1 59  ? 271.380 269.728 249.664 1.00 21.69  ? 59  ILE A N   1 
ATOM   198   C  CA  . ILE A 1 59  ? 270.489 270.855 249.915 1.00 23.54  ? 59  ILE A CA  1 
ATOM   199   C  C   . ILE A 1 59  ? 270.480 271.140 251.407 1.00 28.47  ? 59  ILE A C   1 
ATOM   200   O  O   . ILE A 1 59  ? 270.725 270.252 252.224 1.00 30.14  ? 59  ILE A O   1 
ATOM   201   C  CB  . ILE A 1 59  ? 269.063 270.575 249.375 1.00 27.04  ? 59  ILE A CB  1 
ATOM   202   C  CG1 . ILE A 1 59  ? 268.221 271.851 249.404 1.00 24.43  ? 59  ILE A CG1 1 
ATOM   203   C  CG2 . ILE A 1 59  ? 268.396 269.471 250.177 1.00 23.71  ? 59  ILE A CG2 1 
ATOM   204   C  CD1 . ILE A 1 59  ? 266.899 271.726 248.689 1.00 25.34  ? 59  ILE A CD1 1 
ATOM   205   N  N   . VAL A 1 60  ? 270.186 272.389 251.760 1.00 33.76  ? 60  VAL A N   1 
ATOM   206   C  CA  . VAL A 1 60  ? 270.074 272.805 253.153 1.00 29.04  ? 60  VAL A CA  1 
ATOM   207   C  C   . VAL A 1 60  ? 268.596 272.738 253.526 1.00 31.21  ? 60  VAL A C   1 
ATOM   208   O  O   . VAL A 1 60  ? 267.823 273.646 253.222 1.00 38.23  ? 60  VAL A O   1 
ATOM   209   C  CB  . VAL A 1 60  ? 270.653 274.204 253.377 1.00 29.65  ? 60  VAL A CB  1 
ATOM   210   C  CG1 . VAL A 1 60  ? 270.624 274.563 254.854 1.00 31.25  ? 60  VAL A CG1 1 
ATOM   211   C  CG2 . VAL A 1 60  ? 272.070 274.288 252.835 1.00 30.48  ? 60  VAL A CG2 1 
ATOM   212   N  N   . LEU A 1 61  ? 268.201 271.649 254.183 1.00 34.26  ? 61  LEU A N   1 
ATOM   213   C  CA  . LEU A 1 61  ? 266.835 271.523 254.664 1.00 31.33  ? 61  LEU A CA  1 
ATOM   214   C  C   . LEU A 1 61  ? 266.544 272.594 255.707 1.00 37.25  ? 61  LEU A C   1 
ATOM   215   O  O   . LEU A 1 61  ? 267.405 272.956 256.513 1.00 40.08  ? 61  LEU A O   1 
ATOM   216   C  CB  . LEU A 1 61  ? 266.607 270.138 255.271 1.00 28.75  ? 61  LEU A CB  1 
ATOM   217   C  CG  . LEU A 1 61  ? 266.923 268.918 254.408 1.00 32.71  ? 61  LEU A CG  1 
ATOM   218   C  CD1 . LEU A 1 61  ? 266.623 267.643 255.177 1.00 31.55  ? 61  LEU A CD1 1 
ATOM   219   C  CD2 . LEU A 1 61  ? 266.154 268.957 253.098 1.00 30.42  ? 61  LEU A CD2 1 
ATOM   220   N  N   . GLY A 1 62  ? 265.310 273.089 255.693 1.00 37.01  ? 62  GLY A N   1 
ATOM   221   C  CA  . GLY A 1 62  ? 264.895 274.124 256.615 1.00 40.26  ? 62  GLY A CA  1 
ATOM   222   C  C   . GLY A 1 62  ? 265.090 275.518 256.059 1.00 47.75  ? 62  GLY A C   1 
ATOM   223   O  O   . GLY A 1 62  ? 265.633 275.734 254.973 1.00 47.38  ? 62  GLY A O   1 
ATOM   224   N  N   . ASN A 1 63  ? 264.623 276.492 256.835 1.00 55.99  ? 63  ASN A N   1 
ATOM   225   C  CA  . ASN A 1 63  ? 264.734 277.900 256.487 1.00 62.19  ? 63  ASN A CA  1 
ATOM   226   C  C   . ASN A 1 63  ? 265.629 278.609 257.493 1.00 62.71  ? 63  ASN A C   1 
ATOM   227   O  O   . ASN A 1 63  ? 265.591 278.312 258.691 1.00 62.59  ? 63  ASN A O   1 
ATOM   228   C  CB  . ASN A 1 63  ? 263.356 278.571 256.435 1.00 62.27  ? 63  ASN A CB  1 
ATOM   229   C  CG  . ASN A 1 63  ? 262.667 278.602 257.786 1.00 66.02  ? 63  ASN A CG  1 
ATOM   230   O  OD1 . ASN A 1 63  ? 263.080 277.922 258.724 1.00 62.99  ? 63  ASN A OD1 1 
ATOM   231   N  ND2 . ASN A 1 63  ? 261.610 279.399 257.890 1.00 70.94  ? 63  ASN A ND2 1 
ATOM   232   N  N   . LYS A 1 64  ? 266.442 279.542 256.996 1.00 64.00  ? 64  LYS A N   1 
ATOM   233   C  CA  . LYS A 1 64  ? 267.366 280.265 257.862 1.00 65.89  ? 64  LYS A CA  1 
ATOM   234   C  C   . LYS A 1 64  ? 266.647 281.305 258.714 1.00 67.36  ? 64  LYS A C   1 
ATOM   235   O  O   . LYS A 1 64  ? 266.991 281.496 259.885 1.00 66.03  ? 64  LYS A O   1 
ATOM   236   C  CB  . LYS A 1 64  ? 268.459 280.929 257.024 1.00 61.69  ? 64  LYS A CB  1 
ATOM   237   C  CG  . LYS A 1 64  ? 269.509 279.963 256.497 1.00 64.28  ? 64  LYS A CG  1 
ATOM   238   C  CD  . LYS A 1 64  ? 270.172 279.193 257.628 1.00 65.39  ? 64  LYS A CD  1 
ATOM   239   C  CE  . LYS A 1 64  ? 271.647 278.961 257.345 1.00 62.82  ? 64  LYS A CE  1 
ATOM   240   N  NZ  . LYS A 1 64  ? 271.854 278.028 256.203 1.00 55.85  ? 64  LYS A NZ  1 
ATOM   241   N  N   . GLU A 1 65  ? 265.653 281.984 258.148 1.00 68.37  ? 65  GLU A N   1 
ATOM   242   C  CA  . GLU A 1 65  ? 264.942 283.056 258.828 1.00 69.11  ? 65  GLU A CA  1 
ATOM   243   C  C   . GLU A 1 65  ? 263.553 282.585 259.237 1.00 69.52  ? 65  GLU A C   1 
ATOM   244   O  O   . GLU A 1 65  ? 262.857 281.924 258.460 1.00 72.00  ? 65  GLU A O   1 
ATOM   245   C  CB  . GLU A 1 65  ? 264.836 284.295 257.936 1.00 70.27  ? 65  GLU A CB  1 
ATOM   246   C  CG  . GLU A 1 65  ? 264.035 284.082 256.664 1.00 73.52  ? 65  GLU A CG  1 
ATOM   247   C  CD  . GLU A 1 65  ? 262.682 284.764 256.708 1.00 83.23  ? 65  GLU A CD  1 
ATOM   248   O  OE1 . GLU A 1 65  ? 262.617 285.926 257.160 1.00 86.01  ? 65  GLU A OE1 1 
ATOM   249   O  OE2 . GLU A 1 65  ? 261.685 284.138 256.293 1.00 80.85  ? 65  GLU A OE2 1 
ATOM   250   N  N   . ALA A 1 66  ? 263.158 282.928 260.459 1.00 71.51  ? 66  ALA A N   1 
ATOM   251   C  CA  . ALA A 1 66  ? 261.874 282.521 261.006 1.00 71.40  ? 66  ALA A CA  1 
ATOM   252   C  C   . ALA A 1 66  ? 260.831 283.610 260.754 1.00 71.26  ? 66  ALA A C   1 
ATOM   253   O  O   . ALA A 1 66  ? 261.087 284.605 260.072 1.00 69.85  ? 66  ALA A O   1 
ATOM   254   C  CB  . ALA A 1 66  ? 262.014 282.203 262.493 1.00 66.55  ? 66  ALA A CB  1 
ATOM   255   N  N   . ASP A 1 67  ? 259.633 283.425 261.309 1.00 70.35  ? 67  ASP A N   1 
ATOM   256   C  CA  . ASP A 1 67  ? 258.555 284.395 261.155 1.00 64.75  ? 67  ASP A CA  1 
ATOM   257   C  C   . ASP A 1 67  ? 258.504 285.402 262.295 1.00 71.22  ? 67  ASP A C   1 
ATOM   258   O  O   . ASP A 1 67  ? 258.158 286.567 262.068 1.00 72.61  ? 67  ASP A O   1 
ATOM   259   C  CB  . ASP A 1 67  ? 257.206 283.676 261.053 1.00 62.52  ? 67  ASP A CB  1 
ATOM   260   C  CG  . ASP A 1 67  ? 257.256 282.456 260.150 1.00 66.05  ? 67  ASP A CG  1 
ATOM   261   O  OD1 . ASP A 1 67  ? 258.032 281.521 260.441 1.00 65.89  ? 67  ASP A OD1 1 
ATOM   262   O  OD2 . ASP A 1 67  ? 256.512 282.428 259.148 1.00 63.37  ? 67  ASP A OD2 1 
ATOM   263   N  N   . SER A 1 68  ? 258.827 284.973 263.514 1.00 67.97  ? 68  SER A N   1 
ATOM   264   C  CA  . SER A 1 68  ? 258.861 285.841 264.686 1.00 67.37  ? 68  SER A CA  1 
ATOM   265   C  C   . SER A 1 68  ? 257.457 286.194 265.160 1.00 66.56  ? 68  SER A C   1 
ATOM   266   O  O   . SER A 1 68  ? 257.294 286.833 266.203 1.00 71.79  ? 68  SER A O   1 
ATOM   267   C  CB  . SER A 1 68  ? 259.654 287.117 264.395 1.00 72.86  ? 68  SER A CB  1 
ATOM   268   O  OG  . SER A 1 68  ? 259.860 287.859 265.585 1.00 75.28  ? 68  SER A OG  1 
ATOM   269   N  N   . LEU A 1 69  ? 256.439 285.787 264.402 1.00 57.76  ? 69  LEU A N   1 
ATOM   270   C  CA  . LEU A 1 69  ? 255.065 285.832 264.878 1.00 51.31  ? 69  LEU A CA  1 
ATOM   271   C  C   . LEU A 1 69  ? 254.483 284.452 265.131 1.00 46.72  ? 69  LEU A C   1 
ATOM   272   O  O   . LEU A 1 69  ? 253.517 284.336 265.891 1.00 45.98  ? 69  LEU A O   1 
ATOM   273   C  CB  . LEU A 1 69  ? 254.170 286.588 263.885 1.00 55.73  ? 69  LEU A CB  1 
ATOM   274   C  CG  . LEU A 1 69  ? 254.144 288.105 264.091 1.00 56.33  ? 69  LEU A CG  1 
ATOM   275   C  CD1 . LEU A 1 69  ? 253.222 288.787 263.092 1.00 44.24  ? 69  LEU A CD1 1 
ATOM   276   C  CD2 . LEU A 1 69  ? 253.744 288.447 265.520 1.00 50.33  ? 69  LEU A CD2 1 
ATOM   277   N  N   . TRP A 1 70  ? 255.049 283.411 264.521 1.00 44.75  ? 70  TRP A N   1 
ATOM   278   C  CA  . TRP A 1 70  ? 254.679 282.037 264.819 1.00 41.19  ? 70  TRP A CA  1 
ATOM   279   C  C   . TRP A 1 70  ? 255.432 281.479 266.018 1.00 47.15  ? 70  TRP A C   1 
ATOM   280   O  O   . TRP A 1 70  ? 255.100 280.385 266.484 1.00 49.22  ? 70  TRP A O   1 
ATOM   281   C  CB  . TRP A 1 70  ? 254.925 281.151 263.594 1.00 38.94  ? 70  TRP A CB  1 
ATOM   282   C  CG  . TRP A 1 70  ? 253.799 281.162 262.603 1.00 37.12  ? 70  TRP A CG  1 
ATOM   283   C  CD1 . TRP A 1 70  ? 253.642 282.016 261.552 1.00 36.22  ? 70  TRP A CD1 1 
ATOM   284   C  CD2 . TRP A 1 70  ? 252.676 280.273 262.568 1.00 36.51  ? 70  TRP A CD2 1 
ATOM   285   N  NE1 . TRP A 1 70  ? 252.490 281.717 260.867 1.00 33.27  ? 70  TRP A NE1 1 
ATOM   286   C  CE2 . TRP A 1 70  ? 251.878 280.651 261.471 1.00 34.26  ? 70  TRP A CE2 1 
ATOM   287   C  CE3 . TRP A 1 70  ? 252.266 279.196 263.360 1.00 32.34  ? 70  TRP A CE3 1 
ATOM   288   C  CZ2 . TRP A 1 70  ? 250.697 279.991 261.145 1.00 30.43  ? 70  TRP A CZ2 1 
ATOM   289   C  CZ3 . TRP A 1 70  ? 251.093 278.543 263.034 1.00 32.83  ? 70  TRP A CZ3 1 
ATOM   290   C  CH2 . TRP A 1 70  ? 250.322 278.942 261.938 1.00 27.67  ? 70  TRP A CH2 1 
ATOM   291   N  N   . GLY A 1 71  ? 256.436 282.196 266.518 1.00 46.23  ? 71  GLY A N   1 
ATOM   292   C  CA  . GLY A 1 71  ? 257.184 281.740 267.676 1.00 47.11  ? 71  GLY A CA  1 
ATOM   293   C  C   . GLY A 1 71  ? 257.906 280.430 267.468 1.00 51.65  ? 71  GLY A C   1 
ATOM   294   O  O   . GLY A 1 71  ? 258.044 279.647 268.413 1.00 54.26  ? 71  GLY A O   1 
ATOM   295   N  N   . ILE A 1 72  ? 258.375 280.170 266.253 1.00 53.54  ? 72  ILE A N   1 
ATOM   296   C  CA  . ILE A 1 72  ? 259.064 278.922 265.940 1.00 58.08  ? 72  ILE A CA  1 
ATOM   297   C  C   . ILE A 1 72  ? 260.467 279.249 265.443 1.00 60.61  ? 72  ILE A C   1 
ATOM   298   O  O   . ILE A 1 72  ? 260.623 279.801 264.344 1.00 63.96  ? 72  ILE A O   1 
ATOM   299   C  CB  . ILE A 1 72  ? 258.279 278.097 264.908 1.00 53.93  ? 72  ILE A CB  1 
ATOM   300   C  CG1 . ILE A 1 72  ? 256.952 277.626 265.507 1.00 49.72  ? 72  ILE A CG1 1 
ATOM   301   C  CG2 . ILE A 1 72  ? 259.100 276.911 264.437 1.00 50.90  ? 72  ILE A CG2 1 
ATOM   302   C  CD1 . ILE A 1 72  ? 255.781 277.735 264.558 1.00 44.43  ? 72  ILE A CD1 1 
ATOM   303   N  N   . PRO A 1 73  ? 261.509 278.936 266.211 1.00 59.93  ? 73  PRO A N   1 
ATOM   304   C  CA  . PRO A 1 73  ? 262.868 279.286 265.785 1.00 62.66  ? 73  PRO A CA  1 
ATOM   305   C  C   . PRO A 1 73  ? 263.267 278.553 264.514 1.00 63.01  ? 73  PRO A C   1 
ATOM   306   O  O   . PRO A 1 73  ? 262.822 277.435 264.246 1.00 61.28  ? 73  PRO A O   1 
ATOM   307   C  CB  . PRO A 1 73  ? 263.734 278.858 266.975 1.00 61.40  ? 73  PRO A CB  1 
ATOM   308   C  CG  . PRO A 1 73  ? 262.925 277.819 267.678 1.00 56.09  ? 73  PRO A CG  1 
ATOM   309   C  CD  . PRO A 1 73  ? 261.494 278.228 267.502 1.00 55.05  ? 73  PRO A CD  1 
ATOM   310   N  N   . ALA A 1 74  ? 264.117 279.204 263.726 1.00 66.02  ? 74  ALA A N   1 
ATOM   311   C  CA  . ALA A 1 74  ? 264.596 278.611 262.486 1.00 65.94  ? 74  ALA A CA  1 
ATOM   312   C  C   . ALA A 1 74  ? 265.577 277.481 262.771 1.00 63.20  ? 74  ALA A C   1 
ATOM   313   O  O   . ALA A 1 74  ? 266.423 277.579 263.665 1.00 61.69  ? 74  ALA A O   1 
ATOM   314   C  CB  . ALA A 1 74  ? 265.260 279.673 261.611 1.00 65.15  ? 74  ALA A CB  1 
ATOM   315   N  N   . GLU A 1 75  ? 265.458 276.400 262.004 1.00 62.99  ? 75  GLU A N   1 
ATOM   316   C  CA  . GLU A 1 75  ? 266.363 275.262 262.108 1.00 57.71  ? 75  GLU A CA  1 
ATOM   317   C  C   . GLU A 1 75  ? 266.736 274.820 260.703 1.00 55.35  ? 75  GLU A C   1 
ATOM   318   O  O   . GLU A 1 75  ? 265.854 274.532 259.888 1.00 58.88  ? 75  GLU A O   1 
ATOM   319   C  CB  . GLU A 1 75  ? 265.724 274.109 262.887 1.00 57.29  ? 75  GLU A CB  1 
ATOM   320   C  CG  . GLU A 1 75  ? 265.868 274.224 264.399 1.00 64.99  ? 75  GLU A CG  1 
ATOM   321   C  CD  . GLU A 1 75  ? 267.298 274.020 264.870 1.00 71.53  ? 75  GLU A CD  1 
ATOM   322   O  OE1 . GLU A 1 75  ? 267.890 272.973 264.537 1.00 66.57  ? 75  GLU A OE1 1 
ATOM   323   O  OE2 . GLU A 1 75  ? 267.828 274.903 265.576 1.00 69.71  ? 75  GLU A OE2 1 
ATOM   324   N  N   . SER A 1 76  ? 268.035 274.768 260.421 1.00 49.94  ? 76  SER A N   1 
ATOM   325   C  CA  . SER A 1 76  ? 268.531 274.412 259.102 1.00 47.49  ? 76  SER A CA  1 
ATOM   326   C  C   . SER A 1 76  ? 269.640 273.378 259.228 1.00 48.31  ? 76  SER A C   1 
ATOM   327   O  O   . SER A 1 76  ? 270.399 273.369 260.200 1.00 49.89  ? 76  SER A O   1 
ATOM   328   C  CB  . SER A 1 76  ? 269.047 275.643 258.347 1.00 47.70  ? 76  SER A CB  1 
ATOM   329   O  OG  . SER A 1 76  ? 270.352 275.989 258.774 1.00 53.94  ? 76  SER A OG  1 
ATOM   330   N  N   . ARG A 1 77  ? 269.721 272.504 258.230 1.00 41.30  ? 77  ARG A N   1 
ATOM   331   C  CA  . ARG A 1 77  ? 270.742 271.463 258.205 1.00 38.49  ? 77  ARG A CA  1 
ATOM   332   C  C   . ARG A 1 77  ? 271.057 271.056 256.772 1.00 35.37  ? 77  ARG A C   1 
ATOM   333   O  O   . ARG A 1 77  ? 270.154 270.662 256.028 1.00 34.30  ? 77  ARG A O   1 
ATOM   334   C  CB  . ARG A 1 77  ? 270.288 270.246 259.012 1.00 36.02  ? 77  ARG A CB  1 
ATOM   335   C  CG  . ARG A 1 77  ? 271.251 269.073 258.956 1.00 38.59  ? 77  ARG A CG  1 
ATOM   336   C  CD  . ARG A 1 77  ? 271.709 268.668 260.345 1.00 36.74  ? 77  ARG A CD  1 
ATOM   337   N  NE  . ARG A 1 77  ? 272.880 267.801 260.300 1.00 38.84  ? 77  ARG A NE  1 
ATOM   338   C  CZ  . ARG A 1 77  ? 272.847 266.488 260.478 1.00 39.54  ? 77  ARG A CZ  1 
ATOM   339   N  NH1 . ARG A 1 77  ? 271.713 265.849 260.711 1.00 33.59  ? 77  ARG A NH1 1 
ATOM   340   N  NH2 . ARG A 1 77  ? 273.982 265.797 260.422 1.00 41.92  ? 77  ARG A NH2 1 
ATOM   341   N  N   . PRO A 1 78  ? 272.312 271.148 256.339 1.00 34.43  ? 78  PRO A N   1 
ATOM   342   C  CA  . PRO A 1 78  ? 272.657 270.690 254.989 1.00 32.37  ? 78  PRO A CA  1 
ATOM   343   C  C   . PRO A 1 78  ? 272.874 269.185 254.952 1.00 29.66  ? 78  PRO A C   1 
ATOM   344   O  O   . PRO A 1 78  ? 273.512 268.605 255.834 1.00 34.62  ? 78  PRO A O   1 
ATOM   345   C  CB  . PRO A 1 78  ? 273.950 271.452 254.678 1.00 31.49  ? 78  PRO A CB  1 
ATOM   346   C  CG  . PRO A 1 78  ? 274.560 271.718 256.007 1.00 28.99  ? 78  PRO A CG  1 
ATOM   347   C  CD  . PRO A 1 78  ? 273.455 271.769 257.030 1.00 29.30  ? 78  PRO A CD  1 
ATOM   348   N  N   . ILE A 1 79  ? 272.332 268.553 253.911 1.00 25.63  ? 79  ILE A N   1 
ATOM   349   C  CA  . ILE A 1 79  ? 272.363 267.105 253.750 1.00 24.75  ? 79  ILE A CA  1 
ATOM   350   C  C   . ILE A 1 79  ? 272.561 266.774 252.275 1.00 24.54  ? 79  ILE A C   1 
ATOM   351   O  O   . ILE A 1 79  ? 272.501 267.644 251.402 1.00 23.15  ? 79  ILE A O   1 
ATOM   352   C  CB  . ILE A 1 79  ? 271.081 266.428 254.286 1.00 26.13  ? 79  ILE A CB  1 
ATOM   353   C  CG1 . ILE A 1 79  ? 269.845 266.934 253.538 1.00 24.97  ? 79  ILE A CG1 1 
ATOM   354   C  CG2 . ILE A 1 79  ? 270.932 266.665 255.777 1.00 28.28  ? 79  ILE A CG2 1 
ATOM   355   C  CD1 . ILE A 1 79  ? 269.450 266.085 252.354 1.00 19.88  ? 79  ILE A CD1 1 
ATOM   356   N  N   . SER A 1 80  ? 272.801 265.490 252.010 1.00 23.90  ? 80  SER A N   1 
ATOM   357   C  CA  . SER A 1 80  ? 272.982 264.968 250.664 1.00 21.33  ? 80  SER A CA  1 
ATOM   358   C  C   . SER A 1 80  ? 272.126 263.724 250.480 1.00 22.45  ? 80  SER A C   1 
ATOM   359   O  O   . SER A 1 80  ? 271.945 262.942 251.417 1.00 25.70  ? 80  SER A O   1 
ATOM   360   C  CB  . SER A 1 80  ? 274.452 264.630 250.385 1.00 24.26  ? 80  SER A CB  1 
ATOM   361   O  OG  . SER A 1 80  ? 275.210 265.800 250.147 1.00 25.16  ? 80  SER A OG  1 
ATOM   362   N  N   . VAL A 1 81  ? 271.600 263.547 249.270 1.00 22.99  ? 81  VAL A N   1 
ATOM   363   C  CA  . VAL A 1 81  ? 270.799 262.381 248.930 1.00 23.99  ? 81  VAL A CA  1 
ATOM   364   C  C   . VAL A 1 81  ? 271.231 261.860 247.566 1.00 25.20  ? 81  VAL A C   1 
ATOM   365   O  O   . VAL A 1 81  ? 271.786 262.589 246.740 1.00 28.25  ? 81  VAL A O   1 
ATOM   366   C  CB  . VAL A 1 81  ? 269.284 262.682 248.932 1.00 22.88  ? 81  VAL A CB  1 
ATOM   367   C  CG1 . VAL A 1 81  ? 268.805 263.009 250.337 1.00 22.28  ? 81  VAL A CG1 1 
ATOM   368   C  CG2 . VAL A 1 81  ? 268.966 263.814 247.971 1.00 20.61  ? 81  VAL A CG2 1 
ATOM   369   N  N   . ASP A 1 82  ? 270.959 260.581 247.338 1.00 23.22  ? 82  ASP A N   1 
ATOM   370   C  CA  . ASP A 1 82  ? 271.264 259.945 246.068 1.00 25.44  ? 82  ASP A CA  1 
ATOM   371   C  C   . ASP A 1 82  ? 270.061 260.025 245.129 1.00 25.13  ? 82  ASP A C   1 
ATOM   372   O  O   . ASP A 1 82  ? 268.961 260.426 245.514 1.00 27.76  ? 82  ASP A O   1 
ATOM   373   C  CB  . ASP A 1 82  ? 271.686 258.494 246.288 1.00 24.80  ? 82  ASP A CB  1 
ATOM   374   C  CG  . ASP A 1 82  ? 272.859 258.093 245.421 1.00 34.26  ? 82  ASP A CG  1 
ATOM   375   O  OD1 . ASP A 1 82  ? 272.834 258.392 244.210 1.00 35.98  ? 82  ASP A OD1 1 
ATOM   376   O  OD2 . ASP A 1 82  ? 273.813 257.488 245.951 1.00 42.21  ? 82  ASP A OD2 1 
ATOM   377   N  N   . ALA A 1 83  ? 270.287 259.636 243.878 1.00 26.03  ? 83  ALA A N   1 
ATOM   378   C  CA  . ALA A 1 83  ? 269.243 259.698 242.866 1.00 24.65  ? 83  ALA A CA  1 
ATOM   379   C  C   . ALA A 1 83  ? 268.129 258.704 243.173 1.00 26.21  ? 83  ALA A C   1 
ATOM   380   O  O   . ALA A 1 83  ? 268.363 257.627 243.727 1.00 29.00  ? 83  ALA A O   1 
ATOM   381   C  CB  . ALA A 1 83  ? 269.826 259.416 241.484 1.00 25.32  ? 83  ALA A CB  1 
ATOM   382   N  N   . PHE A 1 84  ? 266.903 259.076 242.811 1.00 26.97  ? 84  PHE A N   1 
ATOM   383   C  CA  . PHE A 1 84  ? 265.771 258.183 243.025 1.00 26.86  ? 84  PHE A CA  1 
ATOM   384   C  C   . PHE A 1 84  ? 264.639 258.555 242.079 1.00 25.19  ? 84  PHE A C   1 
ATOM   385   O  O   . PHE A 1 84  ? 264.539 259.696 241.632 1.00 27.79  ? 84  PHE A O   1 
ATOM   386   C  CB  . PHE A 1 84  ? 265.289 258.223 244.483 1.00 24.14  ? 84  PHE A CB  1 
ATOM   387   C  CG  . PHE A 1 84  ? 264.935 259.602 244.978 1.00 23.06  ? 84  PHE A CG  1 
ATOM   388   C  CD1 . PHE A 1 84  ? 265.900 260.424 245.533 1.00 26.89  ? 84  PHE A CD1 1 
ATOM   389   C  CD2 . PHE A 1 84  ? 263.635 260.071 244.898 1.00 22.17  ? 84  PHE A CD2 1 
ATOM   390   C  CE1 . PHE A 1 84  ? 265.579 261.687 245.993 1.00 25.57  ? 84  PHE A CE1 1 
ATOM   391   C  CE2 . PHE A 1 84  ? 263.308 261.334 245.354 1.00 19.75  ? 84  PHE A CE2 1 
ATOM   392   C  CZ  . PHE A 1 84  ? 264.281 262.142 245.903 1.00 24.51  ? 84  PHE A CZ  1 
ATOM   393   N  N   . TRP A 1 85  ? 263.791 257.579 241.773 1.00 26.20  ? 85  TRP A N   1 
ATOM   394   C  CA  . TRP A 1 85  ? 262.579 257.842 241.014 1.00 25.99  ? 85  TRP A CA  1 
ATOM   395   C  C   . TRP A 1 85  ? 261.484 258.329 241.951 1.00 23.79  ? 85  TRP A C   1 
ATOM   396   O  O   . TRP A 1 85  ? 261.300 257.785 243.041 1.00 27.15  ? 85  TRP A O   1 
ATOM   397   C  CB  . TRP A 1 85  ? 262.112 256.580 240.292 1.00 28.03  ? 85  TRP A CB  1 
ATOM   398   C  CG  . TRP A 1 85  ? 263.136 255.971 239.398 1.00 32.61  ? 85  TRP A CG  1 
ATOM   399   C  CD1 . TRP A 1 85  ? 263.985 254.952 239.706 1.00 34.65  ? 85  TRP A CD1 1 
ATOM   400   C  CD2 . TRP A 1 85  ? 263.407 256.324 238.038 1.00 37.27  ? 85  TRP A CD2 1 
ATOM   401   N  NE1 . TRP A 1 85  ? 264.777 254.654 238.626 1.00 40.30  ? 85  TRP A NE1 1 
ATOM   402   C  CE2 . TRP A 1 85  ? 264.441 255.482 237.588 1.00 38.44  ? 85  TRP A CE2 1 
ATOM   403   C  CE3 . TRP A 1 85  ? 262.878 257.271 237.159 1.00 36.30  ? 85  TRP A CE3 1 
ATOM   404   C  CZ2 . TRP A 1 85  ? 264.956 255.559 236.300 1.00 43.15  ? 85  TRP A CZ2 1 
ATOM   405   C  CZ3 . TRP A 1 85  ? 263.390 257.347 235.881 1.00 38.26  ? 85  TRP A CZ3 1 
ATOM   406   C  CH2 . TRP A 1 85  ? 264.420 256.497 235.463 1.00 41.02  ? 85  TRP A CH2 1 
ATOM   407   N  N   . MET A 1 86  ? 260.752 259.352 241.518 1.00 24.51  ? 86  MET A N   1 
ATOM   408   C  CA  . MET A 1 86  ? 259.637 259.898 242.277 1.00 20.77  ? 86  MET A CA  1 
ATOM   409   C  C   . MET A 1 86  ? 258.418 260.010 241.377 1.00 22.86  ? 86  MET A C   1 
ATOM   410   O  O   . MET A 1 86  ? 258.530 260.408 240.214 1.00 27.33  ? 86  MET A O   1 
ATOM   411   C  CB  . MET A 1 86  ? 259.974 261.271 242.867 1.00 19.29  ? 86  MET A CB  1 
ATOM   412   C  CG  . MET A 1 86  ? 259.022 261.713 243.966 1.00 19.23  ? 86  MET A CG  1 
ATOM   413   S  SD  . MET A 1 86  ? 259.403 263.340 244.633 1.00 39.02  ? 86  MET A SD  1 
ATOM   414   C  CE  . MET A 1 86  ? 259.403 262.987 246.386 1.00 17.83  ? 86  MET A CE  1 
ATOM   415   N  N   . ASP A 1 87  ? 257.255 259.665 241.922 1.00 22.53  ? 87  ASP A N   1 
ATOM   416   C  CA  . ASP A 1 87  ? 256.017 259.766 241.163 1.00 20.09  ? 87  ASP A CA  1 
ATOM   417   C  C   . ASP A 1 87  ? 255.819 261.189 240.660 1.00 21.78  ? 87  ASP A C   1 
ATOM   418   O  O   . ASP A 1 87  ? 256.001 262.157 241.404 1.00 24.46  ? 87  ASP A O   1 
ATOM   419   C  CB  . ASP A 1 87  ? 254.831 259.340 242.026 1.00 20.00  ? 87  ASP A CB  1 
ATOM   420   C  CG  . ASP A 1 87  ? 254.517 257.867 241.898 1.00 28.52  ? 87  ASP A CG  1 
ATOM   421   O  OD1 . ASP A 1 87  ? 254.528 257.352 240.762 1.00 31.69  ? 87  ASP A OD1 1 
ATOM   422   O  OD2 . ASP A 1 87  ? 254.254 257.224 242.933 1.00 30.45  ? 87  ASP A OD2 1 
ATOM   423   N  N   . ARG A 1 88  ? 255.441 261.312 239.386 1.00 23.63  ? 88  ARG A N   1 
ATOM   424   C  CA  . ARG A 1 88  ? 255.236 262.632 238.799 1.00 22.51  ? 88  ARG A CA  1 
ATOM   425   C  C   . ARG A 1 88  ? 254.149 263.396 239.540 1.00 21.42  ? 88  ARG A C   1 
ATOM   426   O  O   . ARG A 1 88  ? 254.299 264.588 239.828 1.00 20.37  ? 88  ARG A O   1 
ATOM   427   C  CB  . ARG A 1 88  ? 254.881 262.490 237.321 1.00 26.09  ? 88  ARG A CB  1 
ATOM   428   C  CG  . ARG A 1 88  ? 255.402 263.604 236.440 1.00 33.15  ? 88  ARG A CG  1 
ATOM   429   C  CD  . ARG A 1 88  ? 255.087 263.324 234.984 1.00 35.28  ? 88  ARG A CD  1 
ATOM   430   N  NE  . ARG A 1 88  ? 255.297 261.919 234.657 1.00 41.09  ? 88  ARG A NE  1 
ATOM   431   C  CZ  . ARG A 1 88  ? 256.255 261.471 233.859 1.00 47.18  ? 88  ARG A CZ  1 
ATOM   432   N  NH1 . ARG A 1 88  ? 257.116 262.293 233.284 1.00 47.85  ? 88  ARG A NH1 1 
ATOM   433   N  NH2 . ARG A 1 88  ? 256.355 260.164 233.636 1.00 46.49  ? 88  ARG A NH2 1 
ATOM   434   N  N   . THR A 1 89  ? 253.049 262.726 239.859 1.00 21.78  ? 89  THR A N   1 
ATOM   435   C  CA  . THR A 1 89  ? 251.971 263.301 240.642 1.00 19.83  ? 89  THR A CA  1 
ATOM   436   C  C   . THR A 1 89  ? 251.713 262.426 241.860 1.00 21.97  ? 89  THR A C   1 
ATOM   437   O  O   . THR A 1 89  ? 252.180 261.288 241.951 1.00 27.77  ? 89  THR A O   1 
ATOM   438   C  CB  . THR A 1 89  ? 250.690 263.443 239.810 1.00 23.17  ? 89  THR A CB  1 
ATOM   439   O  OG1 . THR A 1 89  ? 249.990 262.195 239.795 1.00 24.79  ? 89  THR A OG1 1 
ATOM   440   C  CG2 . THR A 1 89  ? 251.021 263.843 238.383 1.00 21.06  ? 89  THR A CG2 1 
ATOM   441   N  N   . GLU A 1 90  ? 250.966 262.977 242.808 1.00 23.18  ? 90  GLU A N   1 
ATOM   442   C  CA  . GLU A 1 90  ? 250.533 262.205 243.958 1.00 22.85  ? 90  GLU A CA  1 
ATOM   443   C  C   . GLU A 1 90  ? 249.481 261.176 243.542 1.00 22.31  ? 90  GLU A C   1 
ATOM   444   O  O   . GLU A 1 90  ? 248.805 261.314 242.519 1.00 26.76  ? 90  GLU A O   1 
ATOM   445   C  CB  . GLU A 1 90  ? 250.009 263.145 245.043 1.00 20.45  ? 90  GLU A CB  1 
ATOM   446   C  CG  . GLU A 1 90  ? 248.773 263.923 244.647 1.00 25.72  ? 90  GLU A CG  1 
ATOM   447   C  CD  . GLU A 1 90  ? 248.821 265.366 245.118 1.00 25.14  ? 90  GLU A CD  1 
ATOM   448   O  OE1 . GLU A 1 90  ? 249.605 265.672 246.037 1.00 23.78  ? 90  GLU A OE1 1 
ATOM   449   O  OE2 . GLU A 1 90  ? 248.076 266.197 244.565 1.00 24.02  ? 90  GLU A OE2 1 
ATOM   450   N  N   . ILE A 1 91  ? 249.358 260.121 244.351 1.00 22.80  ? 91  ILE A N   1 
ATOM   451   C  CA  . ILE A 1 91  ? 248.527 258.981 243.979 1.00 18.93  ? 91  ILE A CA  1 
ATOM   452   C  C   . ILE A 1 91  ? 247.074 259.415 243.857 1.00 19.94  ? 91  ILE A C   1 
ATOM   453   O  O   . ILE A 1 91  ? 246.538 260.111 244.728 1.00 25.51  ? 91  ILE A O   1 
ATOM   454   C  CB  . ILE A 1 91  ? 248.694 257.846 245.002 1.00 20.33  ? 91  ILE A CB  1 
ATOM   455   C  CG1 . ILE A 1 91  ? 250.163 257.419 245.092 1.00 20.45  ? 91  ILE A CG1 1 
ATOM   456   C  CG2 . ILE A 1 91  ? 247.808 256.661 244.647 1.00 18.80  ? 91  ILE A CG2 1 
ATOM   457   C  CD1 . ILE A 1 91  ? 250.624 256.546 243.948 1.00 18.16  ? 91  ILE A CD1 1 
ATOM   458   N  N   . THR A 1 92  ? 246.429 259.001 242.770 1.00 21.77  ? 92  THR A N   1 
ATOM   459   C  CA  . THR A 1 92  ? 245.061 259.389 242.462 1.00 21.60  ? 92  THR A CA  1 
ATOM   460   C  C   . THR A 1 92  ? 244.072 258.337 242.957 1.00 17.65  ? 92  THR A C   1 
ATOM   461   O  O   . THR A 1 92  ? 244.446 257.275 243.456 1.00 18.20  ? 92  THR A O   1 
ATOM   462   C  CB  . THR A 1 92  ? 244.891 259.614 240.955 1.00 20.49  ? 92  THR A CB  1 
ATOM   463   O  OG1 . THR A 1 92  ? 244.988 258.362 240.266 1.00 19.89  ? 92  THR A OG1 1 
ATOM   464   C  CG2 . THR A 1 92  ? 245.961 260.557 240.432 1.00 18.06  ? 92  THR A CG2 1 
ATOM   465   N  N   . ASN A 1 93  ? 242.783 258.659 242.820 1.00 20.24  ? 93  ASN A N   1 
ATOM   466   C  CA  . ASN A 1 93  ? 241.736 257.747 243.271 1.00 19.85  ? 93  ASN A CA  1 
ATOM   467   C  C   . ASN A 1 93  ? 241.761 256.435 242.496 1.00 21.15  ? 93  ASN A C   1 
ATOM   468   O  O   . ASN A 1 93  ? 241.627 255.358 243.085 1.00 24.29  ? 93  ASN A O   1 
ATOM   469   C  CB  . ASN A 1 93  ? 240.366 258.417 243.145 1.00 20.88  ? 93  ASN A CB  1 
ATOM   470   C  CG  . ASN A 1 93  ? 240.073 259.372 244.287 1.00 20.10  ? 93  ASN A CG  1 
ATOM   471   O  OD1 . ASN A 1 93  ? 240.050 258.977 245.451 1.00 22.54  ? 93  ASN A OD1 1 
ATOM   472   N  ND2 . ASN A 1 93  ? 239.843 260.636 243.957 1.00 18.81  ? 93  ASN A ND2 1 
ATOM   473   N  N   . ALA A 1 94  ? 241.920 256.505 241.173 1.00 20.04  ? 94  ALA A N   1 
ATOM   474   C  CA  . ALA A 1 94  ? 241.920 255.293 240.358 1.00 21.85  ? 94  ALA A CA  1 
ATOM   475   C  C   . ALA A 1 94  ? 243.122 254.408 240.668 1.00 26.25  ? 94  ALA A C   1 
ATOM   476   O  O   . ALA A 1 94  ? 243.009 253.174 240.690 1.00 31.42  ? 94  ALA A O   1 
ATOM   477   C  CB  . ALA A 1 94  ? 241.892 255.664 238.877 1.00 23.51  ? 94  ALA A CB  1 
ATOM   478   N  N   . GLN A 1 95  ? 244.285 255.016 240.902 1.00 19.91  ? 95  GLN A N   1 
ATOM   479   C  CA  . GLN A 1 95  ? 245.481 254.232 241.189 1.00 22.05  ? 95  GLN A CA  1 
ATOM   480   C  C   . GLN A 1 95  ? 245.324 253.434 242.478 1.00 22.85  ? 95  GLN A C   1 
ATOM   481   O  O   . GLN A 1 95  ? 245.742 252.273 242.551 1.00 26.75  ? 95  GLN A O   1 
ATOM   482   C  CB  . GLN A 1 95  ? 246.699 255.151 241.255 1.00 23.60  ? 95  GLN A CB  1 
ATOM   483   C  CG  . GLN A 1 95  ? 247.234 255.541 239.886 1.00 23.74  ? 95  GLN A CG  1 
ATOM   484   C  CD  . GLN A 1 95  ? 247.993 256.850 239.903 1.00 23.85  ? 95  GLN A CD  1 
ATOM   485   O  OE1 . GLN A 1 95  ? 248.136 257.483 240.946 1.00 23.91  ? 95  GLN A OE1 1 
ATOM   486   N  NE2 . GLN A 1 95  ? 248.477 257.267 238.741 1.00 20.03  ? 95  GLN A NE2 1 
ATOM   487   N  N   . TYR A 1 96  ? 244.733 254.040 243.509 1.00 19.95  ? 96  TYR A N   1 
ATOM   488   C  CA  . TYR A 1 96  ? 244.461 253.304 244.740 1.00 19.01  ? 96  TYR A CA  1 
ATOM   489   C  C   . TYR A 1 96  ? 243.320 252.310 244.559 1.00 20.42  ? 96  TYR A C   1 
ATOM   490   O  O   . TYR A 1 96  ? 243.309 251.249 245.198 1.00 25.81  ? 96  TYR A O   1 
ATOM   491   C  CB  . TYR A 1 96  ? 244.148 254.279 245.873 1.00 16.88  ? 96  TYR A CB  1 
ATOM   492   C  CG  . TYR A 1 96  ? 244.363 253.698 247.249 1.00 16.58  ? 96  TYR A CG  1 
ATOM   493   C  CD1 . TYR A 1 96  ? 245.613 253.738 247.851 1.00 15.05  ? 96  TYR A CD1 1 
ATOM   494   C  CD2 . TYR A 1 96  ? 243.319 253.110 247.946 1.00 14.25  ? 96  TYR A CD2 1 
ATOM   495   C  CE1 . TYR A 1 96  ? 245.815 253.208 249.107 1.00 14.50  ? 96  TYR A CE1 1 
ATOM   496   C  CE2 . TYR A 1 96  ? 243.512 252.576 249.201 1.00 16.12  ? 96  TYR A CE2 1 
ATOM   497   C  CZ  . TYR A 1 96  ? 244.762 252.628 249.777 1.00 17.86  ? 96  TYR A CZ  1 
ATOM   498   O  OH  . TYR A 1 96  ? 244.957 252.099 251.029 1.00 24.43  ? 96  TYR A OH  1 
ATOM   499   N  N   . ARG A 1 97  ? 242.347 252.640 243.710 1.00 20.82  ? 97  ARG A N   1 
ATOM   500   C  CA  . ARG A 1 97  ? 241.276 251.698 243.418 1.00 21.85  ? 97  ARG A CA  1 
ATOM   501   C  C   . ARG A 1 97  ? 241.818 250.436 242.768 1.00 23.77  ? 97  ARG A C   1 
ATOM   502   O  O   . ARG A 1 97  ? 241.239 249.361 242.929 1.00 25.84  ? 97  ARG A O   1 
ATOM   503   C  CB  . ARG A 1 97  ? 240.226 252.352 242.521 1.00 25.74  ? 97  ARG A CB  1 
ATOM   504   C  CG  . ARG A 1 97  ? 238.810 251.888 242.796 1.00 23.43  ? 97  ARG A CG  1 
ATOM   505   C  CD  . ARG A 1 97  ? 237.813 252.595 241.899 1.00 27.73  ? 97  ARG A CD  1 
ATOM   506   N  NE  . ARG A 1 97  ? 237.547 253.957 242.342 1.00 28.14  ? 97  ARG A NE  1 
ATOM   507   C  CZ  . ARG A 1 97  ? 237.786 255.040 241.616 1.00 27.13  ? 97  ARG A CZ  1 
ATOM   508   N  NH1 . ARG A 1 97  ? 238.304 254.956 240.403 1.00 28.73  ? 97  ARG A NH1 1 
ATOM   509   N  NH2 . ARG A 1 97  ? 237.502 256.236 242.122 1.00 29.60  ? 97  ARG A NH2 1 
ATOM   510   N  N   . GLN A 1 98  ? 242.918 250.548 242.027 1.00 25.14  ? 98  GLN A N   1 
ATOM   511   C  CA  . GLN A 1 98  ? 243.562 249.351 241.491 1.00 26.32  ? 98  GLN A CA  1 
ATOM   512   C  C   . GLN A 1 98  ? 243.996 248.414 242.615 1.00 26.07  ? 98  GLN A C   1 
ATOM   513   O  O   . GLN A 1 98  ? 243.766 247.200 242.558 1.00 28.28  ? 98  GLN A O   1 
ATOM   514   C  CB  . GLN A 1 98  ? 244.757 249.745 240.626 1.00 29.78  ? 98  GLN A CB  1 
ATOM   515   C  CG  . GLN A 1 98  ? 244.881 248.949 239.347 1.00 36.94  ? 98  GLN A CG  1 
ATOM   516   C  CD  . GLN A 1 98  ? 246.292 248.944 238.808 1.00 47.98  ? 98  GLN A CD  1 
ATOM   517   O  OE1 . GLN A 1 98  ? 246.982 249.960 238.838 1.00 53.13  ? 98  GLN A OE1 1 
ATOM   518   N  NE2 . GLN A 1 98  ? 246.734 247.793 238.318 1.00 50.21  ? 98  GLN A NE2 1 
ATOM   519   N  N   . PHE A 1 99  ? 244.624 248.969 243.653 1.00 25.33  ? 99  PHE A N   1 
ATOM   520   C  CA  . PHE A 1 99  ? 245.030 248.176 244.811 1.00 21.73  ? 99  PHE A CA  1 
ATOM   521   C  C   . PHE A 1 99  ? 243.821 247.577 245.521 1.00 24.24  ? 99  PHE A C   1 
ATOM   522   O  O   . PHE A 1 99  ? 243.827 246.397 245.904 1.00 29.61  ? 99  PHE A O   1 
ATOM   523   C  CB  . PHE A 1 99  ? 245.835 249.067 245.758 1.00 18.92  ? 99  PHE A CB  1 
ATOM   524   C  CG  . PHE A 1 99  ? 246.219 248.412 247.050 1.00 20.25  ? 99  PHE A CG  1 
ATOM   525   C  CD1 . PHE A 1 99  ? 246.683 247.112 247.079 1.00 20.07  ? 99  PHE A CD1 1 
ATOM   526   C  CD2 . PHE A 1 99  ? 246.129 249.113 248.239 1.00 17.48  ? 99  PHE A CD2 1 
ATOM   527   C  CE1 . PHE A 1 99  ? 247.048 246.522 248.269 1.00 18.77  ? 99  PHE A CE1 1 
ATOM   528   C  CE2 . PHE A 1 99  ? 246.491 248.528 249.430 1.00 17.23  ? 99  PHE A CE2 1 
ATOM   529   C  CZ  . PHE A 1 99  ? 246.950 247.230 249.446 1.00 16.34  ? 99  PHE A CZ  1 
ATOM   530   N  N   . VAL A 1 100 ? 242.771 248.379 245.698 1.00 19.59  ? 100 VAL A N   1 
ATOM   531   C  CA  . VAL A 1 100 ? 241.569 247.894 246.372 1.00 20.22  ? 100 VAL A CA  1 
ATOM   532   C  C   . VAL A 1 100 ? 240.940 246.751 245.585 1.00 25.54  ? 100 VAL A C   1 
ATOM   533   O  O   . VAL A 1 100 ? 240.508 245.742 246.158 1.00 29.01  ? 100 VAL A O   1 
ATOM   534   C  CB  . VAL A 1 100 ? 240.574 249.050 246.587 1.00 22.06  ? 100 VAL A CB  1 
ATOM   535   C  CG1 . VAL A 1 100 ? 239.229 248.514 247.046 1.00 22.80  ? 100 VAL A CG1 1 
ATOM   536   C  CG2 . VAL A 1 100 ? 241.127 250.047 247.593 1.00 21.50  ? 100 VAL A CG2 1 
ATOM   537   N  N   . TYR A 1 101 ? 240.873 246.891 244.260 1.00 23.91  ? 101 TYR A N   1 
ATOM   538   C  CA  . TYR A 1 101 ? 240.284 245.854 243.423 1.00 21.64  ? 101 TYR A CA  1 
ATOM   539   C  C   . TYR A 1 101 ? 241.136 244.595 243.421 1.00 27.29  ? 101 TYR A C   1 
ATOM   540   O  O   . TYR A 1 101 ? 240.602 243.482 243.375 1.00 31.37  ? 101 TYR A O   1 
ATOM   541   C  CB  . TYR A 1 101 ? 240.094 246.374 241.999 1.00 27.67  ? 101 TYR A CB  1 
ATOM   542   C  CG  . TYR A 1 101 ? 238.911 247.299 241.834 1.00 31.61  ? 101 TYR A CG  1 
ATOM   543   C  CD1 . TYR A 1 101 ? 238.079 247.595 242.905 1.00 28.33  ? 101 TYR A CD1 1 
ATOM   544   C  CD2 . TYR A 1 101 ? 238.628 247.877 240.606 1.00 31.10  ? 101 TYR A CD2 1 
ATOM   545   C  CE1 . TYR A 1 101 ? 237.000 248.440 242.755 1.00 26.68  ? 101 TYR A CE1 1 
ATOM   546   C  CE2 . TYR A 1 101 ? 237.550 248.723 240.447 1.00 32.29  ? 101 TYR A CE2 1 
ATOM   547   C  CZ  . TYR A 1 101 ? 236.740 249.002 241.525 1.00 35.45  ? 101 TYR A CZ  1 
ATOM   548   O  OH  . TYR A 1 101 ? 235.664 249.844 241.374 1.00 43.99  ? 101 TYR A OH  1 
ATOM   549   N  N   . TYR A 1 102 ? 242.463 244.740 243.460 1.00 27.88  ? 102 TYR A N   1 
ATOM   550   C  CA  . TYR A 1 102 ? 243.308 243.557 243.580 1.00 23.85  ? 102 TYR A CA  1 
ATOM   551   C  C   . TYR A 1 102 ? 243.019 242.813 244.876 1.00 24.07  ? 102 TYR A C   1 
ATOM   552   O  O   . TYR A 1 102 ? 242.903 241.582 244.887 1.00 29.98  ? 102 TYR A O   1 
ATOM   553   C  CB  . TYR A 1 102 ? 244.788 243.932 243.510 1.00 24.25  ? 102 TYR A CB  1 
ATOM   554   C  CG  . TYR A 1 102 ? 245.686 242.779 243.902 1.00 27.39  ? 102 TYR A CG  1 
ATOM   555   C  CD1 . TYR A 1 102 ? 246.111 241.854 242.959 1.00 26.57  ? 102 TYR A CD1 1 
ATOM   556   C  CD2 . TYR A 1 102 ? 246.087 242.600 245.220 1.00 27.52  ? 102 TYR A CD2 1 
ATOM   557   C  CE1 . TYR A 1 102 ? 246.919 240.794 243.315 1.00 29.26  ? 102 TYR A CE1 1 
ATOM   558   C  CE2 . TYR A 1 102 ? 246.893 241.544 245.584 1.00 27.16  ? 102 TYR A CE2 1 
ATOM   559   C  CZ  . TYR A 1 102 ? 247.307 240.643 244.628 1.00 33.90  ? 102 TYR A CZ  1 
ATOM   560   O  OH  . TYR A 1 102 ? 248.113 239.589 244.986 1.00 43.57  ? 102 TYR A OH  1 
ATOM   561   N  N   . VAL A 1 103 ? 242.924 243.546 245.987 1.00 24.30  ? 103 VAL A N   1 
ATOM   562   C  CA  . VAL A 1 103 ? 242.631 242.896 247.263 1.00 21.89  ? 103 VAL A CA  1 
ATOM   563   C  C   . VAL A 1 103 ? 241.280 242.195 247.200 1.00 24.34  ? 103 VAL A C   1 
ATOM   564   O  O   . VAL A 1 103 ? 241.130 241.050 247.654 1.00 27.53  ? 103 VAL A O   1 
ATOM   565   C  CB  . VAL A 1 103 ? 242.692 243.917 248.415 1.00 22.94  ? 103 VAL A CB  1 
ATOM   566   C  CG1 . VAL A 1 103 ? 241.902 243.418 249.612 1.00 25.55  ? 103 VAL A CG1 1 
ATOM   567   C  CG2 . VAL A 1 103 ? 244.133 244.189 248.806 1.00 20.94  ? 103 VAL A CG2 1 
ATOM   568   N  N   . ARG A 1 104 ? 240.277 242.868 246.632 1.00 25.27  ? 104 ARG A N   1 
ATOM   569   C  CA  . ARG A 1 104 ? 238.950 242.273 246.506 1.00 24.60  ? 104 ARG A CA  1 
ATOM   570   C  C   . ARG A 1 104 ? 238.998 240.986 245.692 1.00 28.26  ? 104 ARG A C   1 
ATOM   571   O  O   . ARG A 1 104 ? 238.424 239.966 246.087 1.00 32.22  ? 104 ARG A O   1 
ATOM   572   C  CB  . ARG A 1 104 ? 237.993 243.279 245.868 1.00 24.56  ? 104 ARG A CB  1 
ATOM   573   C  CG  . ARG A 1 104 ? 236.647 242.703 245.469 1.00 27.11  ? 104 ARG A CG  1 
ATOM   574   C  CD  . ARG A 1 104 ? 236.036 243.486 244.320 1.00 27.64  ? 104 ARG A CD  1 
ATOM   575   N  NE  . ARG A 1 104 ? 236.837 243.384 243.107 1.00 35.50  ? 104 ARG A NE  1 
ATOM   576   C  CZ  . ARG A 1 104 ? 236.671 244.140 242.031 1.00 33.91  ? 104 ARG A CZ  1 
ATOM   577   N  NH1 . ARG A 1 104 ? 235.728 245.067 241.976 1.00 31.33  ? 104 ARG A NH1 1 
ATOM   578   N  NH2 . ARG A 1 104 ? 237.469 243.962 240.983 1.00 31.95  ? 104 ARG A NH2 1 
ATOM   579   N  N   . ASP A 1 105 ? 239.681 241.018 244.546 1.00 31.26  ? 105 ASP A N   1 
ATOM   580   C  CA  . ASP A 1 105 ? 239.741 239.846 243.681 1.00 29.93  ? 105 ASP A CA  1 
ATOM   581   C  C   . ASP A 1 105 ? 240.469 238.694 244.360 1.00 29.28  ? 105 ASP A C   1 
ATOM   582   O  O   . ASP A 1 105 ? 240.036 237.540 244.272 1.00 33.49  ? 105 ASP A O   1 
ATOM   583   C  CB  . ASP A 1 105 ? 240.417 240.206 242.359 1.00 31.19  ? 105 ASP A CB  1 
ATOM   584   C  CG  . ASP A 1 105 ? 239.536 241.058 241.471 1.00 42.35  ? 105 ASP A CG  1 
ATOM   585   O  OD1 . ASP A 1 105 ? 238.308 241.076 241.694 1.00 45.45  ? 105 ASP A OD1 1 
ATOM   586   O  OD2 . ASP A 1 105 ? 240.069 241.714 240.552 1.00 45.40  ? 105 ASP A OD2 1 
ATOM   587   N  N   . SER A 1 106 ? 241.580 238.983 245.039 1.00 29.31  ? 106 SER A N   1 
ATOM   588   C  CA  . SER A 1 106 ? 242.313 237.919 245.716 1.00 29.47  ? 106 SER A CA  1 
ATOM   589   C  C   . SER A 1 106 ? 241.474 237.286 246.817 1.00 31.57  ? 106 SER A C   1 
ATOM   590   O  O   . SER A 1 106 ? 241.446 236.057 246.957 1.00 35.01  ? 106 SER A O   1 
ATOM   591   C  CB  . SER A 1 106 ? 243.622 238.453 246.291 1.00 29.65  ? 106 SER A CB  1 
ATOM   592   O  OG  . SER A 1 106 ? 243.934 237.748 247.477 1.00 35.62  ? 106 SER A OG  1 
ATOM   593   N  N   . ILE A 1 107 ? 240.781 238.102 247.614 1.00 29.52  ? 107 ILE A N   1 
ATOM   594   C  CA  . ILE A 1 107 ? 239.963 237.537 248.682 1.00 33.13  ? 107 ILE A CA  1 
ATOM   595   C  C   . ILE A 1 107 ? 238.803 236.736 248.102 1.00 34.76  ? 107 ILE A C   1 
ATOM   596   O  O   . ILE A 1 107 ? 238.441 235.672 248.624 1.00 37.25  ? 107 ILE A O   1 
ATOM   597   C  CB  . ILE A 1 107 ? 239.476 238.646 249.632 1.00 34.83  ? 107 ILE A CB  1 
ATOM   598   C  CG1 . ILE A 1 107 ? 240.527 238.910 250.710 1.00 35.58  ? 107 ILE A CG1 1 
ATOM   599   C  CG2 . ILE A 1 107 ? 238.164 238.248 250.276 1.00 32.11  ? 107 ILE A CG2 1 
ATOM   600   C  CD1 . ILE A 1 107 ? 240.587 240.344 251.167 1.00 31.09  ? 107 ILE A CD1 1 
ATOM   601   N  N   . ILE A 1 108 ? 238.207 237.220 247.009 1.00 33.08  ? 108 ILE A N   1 
ATOM   602   C  CA  . ILE A 1 108 ? 237.100 236.495 246.392 1.00 35.06  ? 108 ILE A CA  1 
ATOM   603   C  C   . ILE A 1 108 ? 237.575 235.152 245.857 1.00 35.51  ? 108 ILE A C   1 
ATOM   604   O  O   . ILE A 1 108 ? 236.878 234.140 245.981 1.00 37.68  ? 108 ILE A O   1 
ATOM   605   C  CB  . ILE A 1 108 ? 236.446 237.348 245.290 1.00 37.87  ? 108 ILE A CB  1 
ATOM   606   C  CG1 . ILE A 1 108 ? 235.463 238.342 245.906 1.00 33.57  ? 108 ILE A CG1 1 
ATOM   607   C  CG2 . ILE A 1 108 ? 235.737 236.460 244.279 1.00 37.60  ? 108 ILE A CG2 1 
ATOM   608   C  CD1 . ILE A 1 108 ? 234.973 239.395 244.942 1.00 31.79  ? 108 ILE A CD1 1 
ATOM   609   N  N   . ARG A 1 109 ? 238.758 235.122 245.239 1.00 35.45  ? 109 ARG A N   1 
ATOM   610   C  CA  . ARG A 1 109 ? 239.304 233.857 244.755 1.00 35.61  ? 109 ARG A CA  1 
ATOM   611   C  C   . ARG A 1 109 ? 239.628 232.911 245.904 1.00 39.18  ? 109 ARG A C   1 
ATOM   612   O  O   . ARG A 1 109 ? 239.396 231.701 245.802 1.00 41.52  ? 109 ARG A O   1 
ATOM   613   C  CB  . ARG A 1 109 ? 240.544 234.111 243.902 1.00 30.06  ? 109 ARG A CB  1 
ATOM   614   C  CG  . ARG A 1 109 ? 240.238 234.798 242.591 1.00 34.23  ? 109 ARG A CG  1 
ATOM   615   C  CD  . ARG A 1 109 ? 241.444 235.540 242.057 1.00 37.10  ? 109 ARG A CD  1 
ATOM   616   N  NE  . ARG A 1 109 ? 241.226 236.012 240.696 1.00 41.94  ? 109 ARG A NE  1 
ATOM   617   C  CZ  . ARG A 1 109 ? 240.978 235.222 239.661 1.00 45.40  ? 109 ARG A CZ  1 
ATOM   618   N  NH1 . ARG A 1 109 ? 240.916 233.908 239.793 1.00 46.91  ? 109 ARG A NH1 1 
ATOM   619   N  NH2 . ARG A 1 109 ? 240.793 235.764 238.461 1.00 49.53  ? 109 ARG A NH2 1 
ATOM   620   N  N   . GLU A 1 110 ? 240.170 233.437 247.004 1.00 39.48  ? 110 GLU A N   1 
ATOM   621   C  CA  . GLU A 1 110 ? 240.420 232.587 248.163 1.00 36.98  ? 110 GLU A CA  1 
ATOM   622   C  C   . GLU A 1 110 ? 239.127 231.971 248.677 1.00 41.53  ? 110 GLU A C   1 
ATOM   623   O  O   . GLU A 1 110 ? 239.102 230.801 249.074 1.00 46.03  ? 110 GLU A O   1 
ATOM   624   C  CB  . GLU A 1 110 ? 241.111 233.383 249.269 1.00 38.88  ? 110 GLU A CB  1 
ATOM   625   C  CG  . GLU A 1 110 ? 242.608 233.530 249.090 1.00 43.58  ? 110 GLU A CG  1 
ATOM   626   C  CD  . GLU A 1 110 ? 243.382 232.406 249.753 1.00 52.69  ? 110 GLU A CD  1 
ATOM   627   O  OE1 . GLU A 1 110 ? 242.763 231.380 250.101 1.00 57.34  ? 110 GLU A OE1 1 
ATOM   628   O  OE2 . GLU A 1 110 ? 244.610 232.548 249.930 1.00 52.94  ? 110 GLU A OE2 1 
ATOM   629   N  N   . ARG A 1 111 ? 238.042 232.746 248.682 1.00 44.47  ? 111 ARG A N   1 
ATOM   630   C  CA  . ARG A 1 111 ? 236.764 232.208 249.138 1.00 45.94  ? 111 ARG A CA  1 
ATOM   631   C  C   . ARG A 1 111 ? 236.165 231.224 248.139 1.00 45.92  ? 111 ARG A C   1 
ATOM   632   O  O   . ARG A 1 111 ? 235.522 230.251 248.546 1.00 54.21  ? 111 ARG A O   1 
ATOM   633   C  CB  . ARG A 1 111 ? 235.790 233.347 249.425 1.00 42.77  ? 111 ARG A CB  1 
ATOM   634   C  CG  . ARG A 1 111 ? 235.734 233.719 250.892 1.00 43.90  ? 111 ARG A CG  1 
ATOM   635   C  CD  . ARG A 1 111 ? 235.717 235.216 251.091 1.00 42.75  ? 111 ARG A CD  1 
ATOM   636   N  NE  . ARG A 1 111 ? 236.152 235.578 252.433 1.00 43.68  ? 111 ARG A NE  1 
ATOM   637   C  CZ  . ARG A 1 111 ? 235.848 236.718 253.036 1.00 45.26  ? 111 ARG A CZ  1 
ATOM   638   N  NH1 . ARG A 1 111 ? 235.101 237.634 252.443 1.00 47.51  ? 111 ARG A NH1 1 
ATOM   639   N  NH2 . ARG A 1 111 ? 236.302 236.944 254.265 1.00 43.02  ? 111 ARG A NH2 1 
ATOM   640   N  N   . LEU A 1 112 ? 236.356 231.456 246.839 1.00 41.99  ? 112 LEU A N   1 
ATOM   641   C  CA  . LEU A 1 112 ? 235.821 230.541 245.835 1.00 42.11  ? 112 LEU A CA  1 
ATOM   642   C  C   . LEU A 1 112 ? 236.421 229.149 245.987 1.00 50.44  ? 112 LEU A C   1 
ATOM   643   O  O   . LEU A 1 112 ? 235.698 228.148 246.020 1.00 60.47  ? 112 LEU A O   1 
ATOM   644   C  CB  . LEU A 1 112 ? 236.089 231.086 244.432 1.00 48.54  ? 112 LEU A CB  1 
ATOM   645   C  CG  . LEU A 1 112 ? 235.166 232.191 243.920 1.00 46.39  ? 112 LEU A CG  1 
ATOM   646   C  CD1 . LEU A 1 112 ? 235.676 232.729 242.595 1.00 41.71  ? 112 LEU A CD1 1 
ATOM   647   C  CD2 . LEU A 1 112 ? 233.742 231.680 243.784 1.00 47.30  ? 112 LEU A CD2 1 
ATOM   648   N  N   . ALA A 1 113 ? 237.745 229.067 246.072 1.00 49.47  ? 113 ALA A N   1 
ATOM   649   C  CA  . ALA A 1 113 ? 238.430 227.800 246.319 1.00 53.20  ? 113 ALA A CA  1 
ATOM   650   C  C   . ALA A 1 113 ? 238.468 227.485 247.809 1.00 56.25  ? 113 ALA A C   1 
ATOM   651   O  O   . ALA A 1 113 ? 239.519 227.222 248.390 1.00 64.80  ? 113 ALA A O   1 
ATOM   652   C  CB  . ALA A 1 113 ? 239.834 227.843 245.730 1.00 56.22  ? 113 ALA A CB  1 
ATOM   653   N  N   . ASP A 1 114 ? 237.294 227.515 248.440 1.00 58.49  ? 114 ASP A N   1 
ATOM   654   C  CA  . ASP A 1 114 ? 237.169 227.301 249.867 1.00 62.28  ? 114 ASP A CA  1 
ATOM   655   C  C   . ASP A 1 114 ? 236.003 226.346 250.094 1.00 70.72  ? 114 ASP A C   1 
ATOM   656   O  O   . ASP A 1 114 ? 234.911 226.562 249.536 1.00 69.42  ? 114 ASP A O   1 
ATOM   657   C  CB  . ASP A 1 114 ? 236.943 228.616 250.615 1.00 60.69  ? 114 ASP A CB  1 
ATOM   658   C  CG  . ASP A 1 114 ? 237.178 228.487 252.105 1.00 68.21  ? 114 ASP A CG  1 
ATOM   659   O  OD1 . ASP A 1 114 ? 237.789 227.483 252.526 1.00 69.99  ? 114 ASP A OD1 1 
ATOM   660   O  OD2 . ASP A 1 114 ? 236.755 229.391 252.856 1.00 69.72  ? 114 ASP A OD2 1 
ATOM   661   N  N   . PRO A 1 115 ? 236.194 225.289 250.884 1.00 72.05  ? 115 PRO A N   1 
ATOM   662   C  CA  . PRO A 1 115 ? 235.075 224.368 251.137 1.00 69.05  ? 115 PRO A CA  1 
ATOM   663   C  C   . PRO A 1 115 ? 233.845 225.051 251.708 1.00 72.50  ? 115 PRO A C   1 
ATOM   664   O  O   . PRO A 1 115 ? 232.719 224.669 251.367 1.00 75.76  ? 115 PRO A O   1 
ATOM   665   C  CB  . PRO A 1 115 ? 235.679 223.362 252.125 1.00 65.14  ? 115 PRO A CB  1 
ATOM   666   C  CG  . PRO A 1 115 ? 237.133 223.356 251.799 1.00 69.01  ? 115 PRO A CG  1 
ATOM   667   C  CD  . PRO A 1 115 ? 237.475 224.763 251.384 1.00 67.58  ? 115 PRO A CD  1 
ATOM   668   N  N   . ALA A 1 116 ? 234.025 226.052 252.572 1.00 72.57  ? 116 ALA A N   1 
ATOM   669   C  CA  . ALA A 1 116 ? 232.879 226.674 253.229 1.00 74.33  ? 116 ALA A CA  1 
ATOM   670   C  C   . ALA A 1 116 ? 231.965 227.360 252.220 1.00 73.75  ? 116 ALA A C   1 
ATOM   671   O  O   . ALA A 1 116 ? 230.757 227.099 252.182 1.00 73.32  ? 116 ALA A O   1 
ATOM   672   C  CB  . ALA A 1 116 ? 233.357 227.669 254.286 1.00 68.47  ? 116 ALA A CB  1 
ATOM   673   N  N   . TYR A 1 117 ? 232.524 228.239 251.391 1.00 73.60  ? 117 TYR A N   1 
ATOM   674   C  CA  . TYR A 1 117 ? 231.723 228.958 250.405 1.00 69.73  ? 117 TYR A CA  1 
ATOM   675   C  C   . TYR A 1 117 ? 231.500 228.115 249.153 1.00 74.36  ? 117 TYR A C   1 
ATOM   676   O  O   . TYR A 1 117 ? 230.361 227.775 248.818 1.00 82.96  ? 117 TYR A O   1 
ATOM   677   C  CB  . TYR A 1 117 ? 232.400 230.287 250.047 1.00 62.85  ? 117 TYR A CB  1 
ATOM   678   C  CG  . TYR A 1 117 ? 232.436 231.289 251.179 1.00 60.93  ? 117 TYR A CG  1 
ATOM   679   C  CD1 . TYR A 1 117 ? 231.379 232.162 251.397 1.00 58.40  ? 117 TYR A CD1 1 
ATOM   680   C  CD2 . TYR A 1 117 ? 233.530 231.363 252.029 1.00 60.17  ? 117 TYR A CD2 1 
ATOM   681   C  CE1 . TYR A 1 117 ? 231.411 233.079 252.430 1.00 58.40  ? 117 TYR A CE1 1 
ATOM   682   C  CE2 . TYR A 1 117 ? 233.571 232.276 253.065 1.00 59.58  ? 117 TYR A CE2 1 
ATOM   683   C  CZ  . TYR A 1 117 ? 232.510 233.131 253.260 1.00 59.98  ? 117 TYR A CZ  1 
ATOM   684   O  OH  . TYR A 1 117 ? 232.550 234.041 254.291 1.00 58.20  ? 117 TYR A OH  1 
ATOM   685   N  N   . GLY A 1 118 ? 232.581 227.765 248.464 1.00 69.86  ? 118 GLY A N   1 
ATOM   686   C  CA  . GLY A 1 118 ? 232.498 226.953 247.268 1.00 70.97  ? 118 GLY A CA  1 
ATOM   687   C  C   . GLY A 1 118 ? 233.156 225.598 247.421 1.00 75.64  ? 118 GLY A C   1 
ATOM   688   O  O   . GLY A 1 118 ? 232.573 224.668 247.986 1.00 74.89  ? 118 GLY A O   1 
ATOM   689   N  N   . GLY A 1 119 ? 234.380 225.482 246.914 1.00 72.41  ? 119 GLY A N   1 
ATOM   690   C  CA  . GLY A 1 119 ? 235.114 224.234 246.943 1.00 68.84  ? 119 GLY A CA  1 
ATOM   691   C  C   . GLY A 1 119 ? 235.838 223.986 245.637 1.00 75.42  ? 119 GLY A C   1 
ATOM   692   O  O   . GLY A 1 119 ? 236.657 223.068 245.532 1.00 80.14  ? 119 GLY A O   1 
ATOM   693   N  N   . ASN A 1 120 ? 235.541 224.809 244.632 1.00 68.06  ? 120 ASN A N   1 
ATOM   694   C  CA  . ASN A 1 120 ? 236.164 224.684 243.322 1.00 65.87  ? 120 ASN A CA  1 
ATOM   695   C  C   . ASN A 1 120 ? 237.677 224.818 243.433 1.00 68.94  ? 120 ASN A C   1 
ATOM   696   O  O   . ASN A 1 120 ? 238.190 225.887 243.780 1.00 69.36  ? 120 ASN A O   1 
ATOM   697   C  CB  . ASN A 1 120 ? 235.599 225.734 242.364 1.00 67.19  ? 120 ASN A CB  1 
ATOM   698   C  CG  . ASN A 1 120 ? 236.034 225.511 240.931 1.00 69.87  ? 120 ASN A CG  1 
ATOM   699   O  OD1 . ASN A 1 120 ? 236.785 224.582 240.634 1.00 73.91  ? 120 ASN A OD1 1 
ATOM   700   N  ND2 . ASN A 1 120 ? 235.562 226.365 240.031 1.00 62.58  ? 120 ASN A ND2 1 
ATOM   701   N  N   . GLU A 1 121 ? 238.399 223.737 243.135 1.00 72.29  ? 121 GLU A N   1 
ATOM   702   C  CA  . GLU A 1 121 ? 239.849 223.718 243.268 1.00 71.38  ? 121 GLU A CA  1 
ATOM   703   C  C   . GLU A 1 121 ? 240.568 224.390 242.106 1.00 69.46  ? 121 GLU A C   1 
ATOM   704   O  O   . GLU A 1 121 ? 241.777 224.622 242.202 1.00 72.36  ? 121 GLU A O   1 
ATOM   705   C  CB  . GLU A 1 121 ? 240.343 222.276 243.402 1.00 77.28  ? 121 GLU A CB  1 
ATOM   706   C  CG  . GLU A 1 121 ? 239.494 221.413 244.320 1.00 78.68  ? 121 GLU A CG  1 
ATOM   707   C  CD  . GLU A 1 121 ? 239.556 221.866 245.764 1.00 84.77  ? 121 GLU A CD  1 
ATOM   708   O  OE1 . GLU A 1 121 ? 240.380 222.750 246.076 1.00 85.70  ? 121 GLU A OE1 1 
ATOM   709   O  OE2 . GLU A 1 121 ? 238.780 221.336 246.588 1.00 82.75  ? 121 GLU A OE2 1 
ATOM   710   N  N   . GLU A 1 122 ? 239.864 224.703 241.017 1.00 66.61  ? 122 GLU A N   1 
ATOM   711   C  CA  . GLU A 1 122 ? 240.514 225.336 239.876 1.00 71.67  ? 122 GLU A CA  1 
ATOM   712   C  C   . GLU A 1 122 ? 241.039 226.726 240.210 1.00 73.02  ? 122 GLU A C   1 
ATOM   713   O  O   . GLU A 1 122 ? 241.867 227.259 239.463 1.00 73.68  ? 122 GLU A O   1 
ATOM   714   C  CB  . GLU A 1 122 ? 239.545 225.417 238.697 1.00 73.45  ? 122 GLU A CB  1 
ATOM   715   C  CG  . GLU A 1 122 ? 239.516 224.178 237.819 1.00 76.97  ? 122 GLU A CG  1 
ATOM   716   C  CD  . GLU A 1 122 ? 238.222 224.053 237.041 1.00 81.64  ? 122 GLU A CD  1 
ATOM   717   O  OE1 . GLU A 1 122 ? 237.327 224.900 237.239 1.00 78.82  ? 122 GLU A OE1 1 
ATOM   718   O  OE2 . GLU A 1 122 ? 238.099 223.111 236.231 1.00 85.27  ? 122 GLU A OE2 1 
ATOM   719   N  N   . TYR A 1 123 ? 240.583 227.321 241.309 1.00 66.91  ? 123 TYR A N   1 
ATOM   720   C  CA  . TYR A 1 123 ? 241.005 228.657 241.704 1.00 62.06  ? 123 TYR A CA  1 
ATOM   721   C  C   . TYR A 1 123 ? 242.231 228.658 242.607 1.00 65.44  ? 123 TYR A C   1 
ATOM   722   O  O   . TYR A 1 123 ? 242.713 229.736 242.966 1.00 66.38  ? 123 TYR A O   1 
ATOM   723   C  CB  . TYR A 1 123 ? 239.855 229.387 242.406 1.00 57.50  ? 123 TYR A CB  1 
ATOM   724   C  CG  . TYR A 1 123 ? 238.742 229.807 241.477 1.00 57.32  ? 123 TYR A CG  1 
ATOM   725   C  CD1 . TYR A 1 123 ? 238.924 230.838 240.567 1.00 56.03  ? 123 TYR A CD1 1 
ATOM   726   C  CD2 . TYR A 1 123 ? 237.509 229.172 241.510 1.00 57.98  ? 123 TYR A CD2 1 
ATOM   727   C  CE1 . TYR A 1 123 ? 237.910 231.225 239.716 1.00 59.72  ? 123 TYR A CE1 1 
ATOM   728   C  CE2 . TYR A 1 123 ? 236.490 229.551 240.663 1.00 57.76  ? 123 TYR A CE2 1 
ATOM   729   C  CZ  . TYR A 1 123 ? 236.694 230.578 239.769 1.00 58.26  ? 123 TYR A CZ  1 
ATOM   730   O  OH  . TYR A 1 123 ? 235.678 230.959 238.924 1.00 59.19  ? 123 TYR A OH  1 
ATOM   731   N  N   . LYS A 1 124 ? 242.747 227.487 242.982 1.00 65.31  ? 124 LYS A N   1 
ATOM   732   C  CA  . LYS A 1 124 ? 243.900 227.393 243.882 1.00 65.30  ? 124 LYS A CA  1 
ATOM   733   C  C   . LYS A 1 124 ? 244.827 226.300 243.351 1.00 71.90  ? 124 LYS A C   1 
ATOM   734   O  O   . LYS A 1 124 ? 244.667 225.122 243.679 1.00 75.86  ? 124 LYS A O   1 
ATOM   735   C  CB  . LYS A 1 124 ? 243.458 227.114 245.312 1.00 61.95  ? 124 LYS A CB  1 
ATOM   736   C  CG  . LYS A 1 124 ? 244.576 227.191 246.335 1.00 61.97  ? 124 LYS A CG  1 
ATOM   737   C  CD  . LYS A 1 124 ? 244.765 228.606 246.846 1.00 61.71  ? 124 LYS A CD  1 
ATOM   738   C  CE  . LYS A 1 124 ? 245.010 228.617 248.345 1.00 63.63  ? 124 LYS A CE  1 
ATOM   739   N  NZ  . LYS A 1 124 ? 243.749 228.423 249.112 1.00 69.84  ? 124 LYS A NZ  1 
ATOM   740   N  N   . ILE A 1 125 ? 245.799 226.703 242.530 1.00 72.88  ? 125 ILE A N   1 
ATOM   741   C  CA  . ILE A 1 125 ? 246.775 225.755 242.007 1.00 78.31  ? 125 ILE A CA  1 
ATOM   742   C  C   . ILE A 1 125 ? 247.608 225.198 243.151 1.00 82.12  ? 125 ILE A C   1 
ATOM   743   O  O   . ILE A 1 125 ? 248.109 225.946 244.000 1.00 78.37  ? 125 ILE A O   1 
ATOM   744   C  CB  . ILE A 1 125 ? 247.659 226.428 240.947 1.00 75.42  ? 125 ILE A CB  1 
ATOM   745   C  CG1 . ILE A 1 125 ? 246.797 227.128 239.895 1.00 72.98  ? 125 ILE A CG1 1 
ATOM   746   C  CG2 . ILE A 1 125 ? 248.584 225.411 240.303 1.00 76.28  ? 125 ILE A CG2 1 
ATOM   747   C  CD1 . ILE A 1 125 ? 247.469 227.262 238.545 1.00 68.59  ? 125 ILE A CD1 1 
ATOM   748   N  N   . THR A 1 126 ? 247.765 223.875 243.175 1.00 89.98  ? 126 THR A N   1 
ATOM   749   C  CA  . THR A 1 126 ? 248.535 223.222 244.224 1.00 94.48  ? 126 THR A CA  1 
ATOM   750   C  C   . THR A 1 126 ? 249.475 222.142 243.710 1.00 101.66 ? 126 THR A C   1 
ATOM   751   O  O   . THR A 1 126 ? 250.098 221.457 244.528 1.00 101.87 ? 126 THR A O   1 
ATOM   752   C  CB  . THR A 1 126 ? 247.598 222.607 245.277 1.00 91.16  ? 126 THR A CB  1 
ATOM   753   O  OG1 . THR A 1 126 ? 246.927 221.472 244.715 1.00 93.35  ? 126 THR A OG1 1 
ATOM   754   C  CG2 . THR A 1 126 ? 246.566 223.624 245.733 1.00 86.70  ? 126 THR A CG2 1 
ATOM   755   N  N   . GLU A 1 127 ? 249.599 221.963 242.397 1.00 106.68 ? 127 GLU A N   1 
ATOM   756   C  CA  . GLU A 1 127 ? 250.457 220.924 241.848 1.00 112.57 ? 127 GLU A CA  1 
ATOM   757   C  C   . GLU A 1 127 ? 250.977 221.365 240.490 1.00 114.13 ? 127 GLU A C   1 
ATOM   758   O  O   . GLU A 1 127 ? 250.389 222.221 239.824 1.00 111.89 ? 127 GLU A O   1 
ATOM   759   C  CB  . GLU A 1 127 ? 249.713 219.589 241.715 1.00 112.41 ? 127 GLU A CB  1 
ATOM   760   C  CG  . GLU A 1 127 ? 249.380 218.916 243.034 1.00 109.32 ? 127 GLU A CG  1 
ATOM   761   C  CD  . GLU A 1 127 ? 248.104 218.101 242.960 1.00 106.70 ? 127 GLU A CD  1 
ATOM   762   O  OE1 . GLU A 1 127 ? 247.040 218.685 242.668 1.00 106.45 ? 127 GLU A OE1 1 
ATOM   763   O  OE2 . GLU A 1 127 ? 248.165 216.875 243.189 1.00 106.12 ? 127 GLU A OE2 1 
ATOM   764   N  N   . ASN A 1 128 ? 252.093 220.767 240.086 1.00 119.99 ? 128 ASN A N   1 
ATOM   765   C  CA  . ASN A 1 128 ? 252.614 220.972 238.747 1.00 125.28 ? 128 ASN A CA  1 
ATOM   766   C  C   . ASN A 1 128 ? 251.849 220.105 237.750 1.00 128.55 ? 128 ASN A C   1 
ATOM   767   O  O   . ASN A 1 128 ? 251.022 219.266 238.118 1.00 128.95 ? 128 ASN A O   1 
ATOM   768   C  CB  . ASN A 1 128 ? 254.108 220.651 238.693 1.00 124.60 ? 128 ASN A CB  1 
ATOM   769   C  CG  . ASN A 1 128 ? 254.959 221.718 239.349 1.00 123.11 ? 128 ASN A CG  1 
ATOM   770   O  OD1 . ASN A 1 128 ? 254.519 222.852 239.536 1.00 121.82 ? 128 ASN A OD1 1 
ATOM   771   N  ND2 . ASN A 1 128 ? 256.189 221.360 239.699 1.00 121.28 ? 128 ASN A ND2 1 
ATOM   772   N  N   . LYS A 1 129 ? 252.136 220.312 236.465 1.00 129.56 ? 129 LYS A N   1 
ATOM   773   C  CA  . LYS A 1 129 ? 251.530 219.471 235.441 1.00 131.38 ? 129 LYS A CA  1 
ATOM   774   C  C   . LYS A 1 129 ? 251.924 218.009 235.601 1.00 132.66 ? 129 LYS A C   1 
ATOM   775   O  O   . LYS A 1 129 ? 251.235 217.130 235.073 1.00 129.86 ? 129 LYS A O   1 
ATOM   776   C  CB  . LYS A 1 129 ? 251.917 219.970 234.048 1.00 127.54 ? 129 LYS A CB  1 
ATOM   777   C  CG  . LYS A 1 129 ? 251.139 221.194 233.594 1.00 124.26 ? 129 LYS A CG  1 
ATOM   778   C  CD  . LYS A 1 129 ? 251.949 222.466 233.780 1.00 127.48 ? 129 LYS A CD  1 
ATOM   779   C  CE  . LYS A 1 129 ? 251.342 223.625 233.007 1.00 123.80 ? 129 LYS A CE  1 
ATOM   780   N  NZ  . LYS A 1 129 ? 252.111 224.885 233.203 1.00 117.19 ? 129 LYS A NZ  1 
ATOM   781   N  N   . PHE A 1 130 ? 253.012 217.733 236.319 1.00 133.14 ? 130 PHE A N   1 
ATOM   782   C  CA  . PHE A 1 130 ? 253.487 216.377 236.547 1.00 131.91 ? 130 PHE A CA  1 
ATOM   783   C  C   . PHE A 1 130 ? 253.146 215.861 237.940 1.00 130.51 ? 130 PHE A C   1 
ATOM   784   O  O   . PHE A 1 130 ? 253.612 214.783 238.321 1.00 129.46 ? 130 PHE A O   1 
ATOM   785   C  CB  . PHE A 1 130 ? 254.998 216.308 236.322 1.00 131.58 ? 130 PHE A CB  1 
ATOM   786   C  CG  . PHE A 1 130 ? 255.557 217.503 235.605 1.00 132.94 ? 130 PHE A CG  1 
ATOM   787   C  CD1 . PHE A 1 130 ? 255.377 217.656 234.241 1.00 133.36 ? 130 PHE A CD1 1 
ATOM   788   C  CD2 . PHE A 1 130 ? 256.263 218.473 236.296 1.00 129.75 ? 130 PHE A CD2 1 
ATOM   789   C  CE1 . PHE A 1 130 ? 255.890 218.755 233.580 1.00 133.15 ? 130 PHE A CE1 1 
ATOM   790   C  CE2 . PHE A 1 130 ? 256.779 219.573 235.641 1.00 130.72 ? 130 PHE A CE2 1 
ATOM   791   C  CZ  . PHE A 1 130 ? 256.592 219.715 234.281 1.00 133.47 ? 130 PHE A CZ  1 
ATOM   792   N  N   . GLY A 1 131 ? 252.348 216.602 238.705 1.00 128.56 ? 131 GLY A N   1 
ATOM   793   C  CA  . GLY A 1 131 ? 251.973 216.180 240.038 1.00 124.77 ? 131 GLY A CA  1 
ATOM   794   C  C   . GLY A 1 131 ? 252.948 216.541 241.134 1.00 125.36 ? 131 GLY A C   1 
ATOM   795   O  O   . GLY A 1 131 ? 252.855 215.978 242.231 1.00 120.08 ? 131 GLY A O   1 
ATOM   796   N  N   . GLU A 1 132 ? 253.876 217.456 240.882 1.00 126.47 ? 132 GLU A N   1 
ATOM   797   C  CA  . GLU A 1 132 ? 254.854 217.835 241.894 1.00 124.60 ? 132 GLU A CA  1 
ATOM   798   C  C   . GLU A 1 132 ? 254.199 218.732 242.938 1.00 121.36 ? 132 GLU A C   1 
ATOM   799   O  O   . GLU A 1 132 ? 253.688 219.802 242.585 1.00 117.94 ? 132 GLU A O   1 
ATOM   800   C  CB  . GLU A 1 132 ? 256.035 218.552 241.254 1.00 124.14 ? 132 GLU A CB  1 
ATOM   801   C  CG  . GLU A 1 132 ? 256.481 217.960 239.925 1.00 127.78 ? 132 GLU A CG  1 
ATOM   802   C  CD  . GLU A 1 132 ? 257.139 216.603 240.079 1.00 128.53 ? 132 GLU A CD  1 
ATOM   803   O  OE1 . GLU A 1 132 ? 256.411 215.588 240.119 1.00 129.14 ? 132 GLU A OE1 1 
ATOM   804   O  OE2 . GLU A 1 132 ? 258.384 216.549 240.158 1.00 123.75 ? 132 GLU A OE2 1 
ATOM   805   N  N   . PRO A 1 133 ? 254.194 218.349 244.218 1.00 118.70 ? 133 PRO A N   1 
ATOM   806   C  CA  . PRO A 1 133 ? 253.579 219.206 245.241 1.00 113.12 ? 133 PRO A CA  1 
ATOM   807   C  C   . PRO A 1 133 ? 254.315 220.526 245.392 1.00 110.09 ? 133 PRO A C   1 
ATOM   808   O  O   . PRO A 1 133 ? 255.475 220.556 245.814 1.00 108.06 ? 133 PRO A O   1 
ATOM   809   C  CB  . PRO A 1 133 ? 253.672 218.360 246.520 1.00 109.10 ? 133 PRO A CB  1 
ATOM   810   C  CG  . PRO A 1 133 ? 253.964 216.965 246.056 1.00 111.67 ? 133 PRO A CG  1 
ATOM   811   C  CD  . PRO A 1 133 ? 254.739 217.108 244.789 1.00 114.28 ? 133 PRO A CD  1 
ATOM   812   N  N   . VAL A 1 134 ? 253.646 221.626 245.051 1.00 108.20 ? 134 VAL A N   1 
ATOM   813   C  CA  . VAL A 1 134 ? 254.271 222.943 245.069 1.00 103.32 ? 134 VAL A CA  1 
ATOM   814   C  C   . VAL A 1 134 ? 253.481 223.863 245.989 1.00 96.15  ? 134 VAL A C   1 
ATOM   815   O  O   . VAL A 1 134 ? 252.479 223.453 246.585 1.00 95.26  ? 134 VAL A O   1 
ATOM   816   C  CB  . VAL A 1 134 ? 254.373 223.527 243.647 1.00 102.89 ? 134 VAL A CB  1 
ATOM   817   C  CG1 . VAL A 1 134 ? 253.026 224.071 243.194 1.00 98.81  ? 134 VAL A CG1 1 
ATOM   818   C  CG2 . VAL A 1 134 ? 255.449 224.602 243.587 1.00 95.21  ? 134 VAL A CG2 1 
ATOM   819   N  N   . THR A 1 135 ? 253.930 225.107 246.113 1.00 93.92  ? 135 THR A N   1 
ATOM   820   C  CA  . THR A 1 135 ? 253.279 226.051 247.008 1.00 91.91  ? 135 THR A CA  1 
ATOM   821   C  C   . THR A 1 135 ? 251.846 226.309 246.549 1.00 88.20  ? 135 THR A C   1 
ATOM   822   O  O   . THR A 1 135 ? 251.616 226.546 245.354 1.00 86.30  ? 135 THR A O   1 
ATOM   823   C  CB  . THR A 1 135 ? 254.056 227.366 247.053 1.00 87.49  ? 135 THR A CB  1 
ATOM   824   O  OG1 . THR A 1 135 ? 253.240 228.387 247.639 1.00 85.07  ? 135 THR A OG1 1 
ATOM   825   C  CG2 . THR A 1 135 ? 254.461 227.789 245.649 1.00 87.38  ? 135 THR A CG2 1 
ATOM   826   N  N   . PRO A 1 136 ? 250.864 226.270 247.450 1.00 82.91  ? 136 PRO A N   1 
ATOM   827   C  CA  . PRO A 1 136 ? 249.477 226.564 247.055 1.00 80.96  ? 136 PRO A CA  1 
ATOM   828   C  C   . PRO A 1 136 ? 249.316 228.045 246.746 1.00 75.02  ? 136 PRO A C   1 
ATOM   829   O  O   . PRO A 1 136 ? 249.521 228.899 247.611 1.00 74.12  ? 136 PRO A O   1 
ATOM   830   C  CB  . PRO A 1 136 ? 248.656 226.147 248.283 1.00 78.41  ? 136 PRO A CB  1 
ATOM   831   C  CG  . PRO A 1 136 ? 249.601 225.389 249.174 1.00 80.57  ? 136 PRO A CG  1 
ATOM   832   C  CD  . PRO A 1 136 ? 250.970 225.891 248.866 1.00 78.53  ? 136 PRO A CD  1 
ATOM   833   N  N   . HIS A 1 137 ? 248.949 228.346 245.504 1.00 73.79  ? 137 HIS A N   1 
ATOM   834   C  CA  . HIS A 1 137 ? 248.788 229.720 245.059 1.00 67.42  ? 137 HIS A CA  1 
ATOM   835   C  C   . HIS A 1 137 ? 247.525 229.832 244.218 1.00 63.71  ? 137 HIS A C   1 
ATOM   836   O  O   . HIS A 1 137 ? 247.051 228.854 243.637 1.00 63.41  ? 137 HIS A O   1 
ATOM   837   C  CB  . HIS A 1 137 ? 250.007 230.200 244.259 1.00 64.51  ? 137 HIS A CB  1 
ATOM   838   C  CG  . HIS A 1 137 ? 250.192 229.486 242.957 1.00 70.11  ? 137 HIS A CG  1 
ATOM   839   N  ND1 . HIS A 1 137 ? 250.521 228.150 242.881 1.00 75.89  ? 137 HIS A ND1 1 
ATOM   840   C  CD2 . HIS A 1 137 ? 250.097 229.923 241.679 1.00 69.83  ? 137 HIS A CD2 1 
ATOM   841   C  CE1 . HIS A 1 137 ? 250.617 227.794 241.613 1.00 75.28  ? 137 HIS A CE1 1 
ATOM   842   N  NE2 . HIS A 1 137 ? 250.364 228.852 240.863 1.00 71.54  ? 137 HIS A NE2 1 
ATOM   843   N  N   . LEU A 1 138 ? 246.981 231.044 244.166 1.00 62.32  ? 138 LEU A N   1 
ATOM   844   C  CA  . LEU A 1 138 ? 245.786 231.296 243.378 1.00 57.17  ? 138 LEU A CA  1 
ATOM   845   C  C   . LEU A 1 138 ? 246.102 231.241 241.888 1.00 58.63  ? 138 LEU A C   1 
ATOM   846   O  O   . LEU A 1 138 ? 247.181 231.636 241.443 1.00 60.43  ? 138 LEU A O   1 
ATOM   847   C  CB  . LEU A 1 138 ? 245.189 232.657 243.732 1.00 49.43  ? 138 LEU A CB  1 
ATOM   848   C  CG  . LEU A 1 138 ? 244.659 232.828 245.156 1.00 47.09  ? 138 LEU A CG  1 
ATOM   849   C  CD1 . LEU A 1 138 ? 244.334 234.286 245.431 1.00 40.62  ? 138 LEU A CD1 1 
ATOM   850   C  CD2 . LEU A 1 138 ? 243.439 231.954 245.379 1.00 45.17  ? 138 LEU A CD2 1 
ATOM   851   N  N   . ASP A 1 139 ? 245.142 230.737 241.116 1.00 60.38  ? 139 ASP A N   1 
ATOM   852   C  CA  . ASP A 1 139 ? 245.254 230.698 239.660 1.00 58.76  ? 139 ASP A CA  1 
ATOM   853   C  C   . ASP A 1 139 ? 244.565 231.939 239.105 1.00 57.78  ? 139 ASP A C   1 
ATOM   854   O  O   . ASP A 1 139 ? 243.343 231.966 238.943 1.00 62.00  ? 139 ASP A O   1 
ATOM   855   C  CB  . ASP A 1 139 ? 244.639 229.420 239.102 1.00 60.77  ? 139 ASP A CB  1 
ATOM   856   C  CG  . ASP A 1 139 ? 244.794 229.310 237.597 1.00 64.85  ? 139 ASP A CG  1 
ATOM   857   O  OD1 . ASP A 1 139 ? 245.788 229.840 237.060 1.00 65.80  ? 139 ASP A OD1 1 
ATOM   858   O  OD2 . ASP A 1 139 ? 243.921 228.693 236.952 1.00 67.17  ? 139 ASP A OD2 1 
ATOM   859   N  N   . TRP A 1 140 ? 245.352 232.970 238.812 1.00 54.31  ? 140 TRP A N   1 
ATOM   860   C  CA  . TRP A 1 140 ? 244.810 234.230 238.322 1.00 54.67  ? 140 TRP A CA  1 
ATOM   861   C  C   . TRP A 1 140 ? 244.423 234.176 236.851 1.00 59.14  ? 140 TRP A C   1 
ATOM   862   O  O   . TRP A 1 140 ? 243.878 235.157 236.336 1.00 59.00  ? 140 TRP A O   1 
ATOM   863   C  CB  . TRP A 1 140 ? 245.821 235.358 238.552 1.00 50.59  ? 140 TRP A CB  1 
ATOM   864   C  CG  . TRP A 1 140 ? 245.982 235.725 239.997 1.00 51.93  ? 140 TRP A CG  1 
ATOM   865   C  CD1 . TRP A 1 140 ? 246.815 235.136 240.901 1.00 52.62  ? 140 TRP A CD1 1 
ATOM   866   C  CD2 . TRP A 1 140 ? 245.290 236.760 240.705 1.00 51.71  ? 140 TRP A CD2 1 
ATOM   867   N  NE1 . TRP A 1 140 ? 246.687 235.739 242.127 1.00 52.00  ? 140 TRP A NE1 1 
ATOM   868   C  CE2 . TRP A 1 140 ? 245.756 236.740 242.034 1.00 50.46  ? 140 TRP A CE2 1 
ATOM   869   C  CE3 . TRP A 1 140 ? 244.322 237.703 240.346 1.00 45.02  ? 140 TRP A CE3 1 
ATOM   870   C  CZ2 . TRP A 1 140 ? 245.288 237.624 243.003 1.00 40.54  ? 140 TRP A CZ2 1 
ATOM   871   C  CZ3 . TRP A 1 140 ? 243.860 238.579 241.308 1.00 38.91  ? 140 TRP A CZ3 1 
ATOM   872   C  CH2 . TRP A 1 140 ? 244.343 238.534 242.621 1.00 38.79  ? 140 TRP A CH2 1 
ATOM   873   N  N   . SER A 1 141 ? 244.691 233.063 236.163 1.00 63.21  ? 141 SER A N   1 
ATOM   874   C  CA  . SER A 1 141 ? 244.372 232.981 234.742 1.00 64.71  ? 141 SER A CA  1 
ATOM   875   C  C   . SER A 1 141 ? 242.875 232.808 234.513 1.00 66.02  ? 141 SER A C   1 
ATOM   876   O  O   . SER A 1 141 ? 242.311 233.411 233.593 1.00 69.73  ? 141 SER A O   1 
ATOM   877   C  CB  . SER A 1 141 ? 245.149 231.837 234.093 1.00 66.85  ? 141 SER A CB  1 
ATOM   878   O  OG  . SER A 1 141 ? 244.870 230.601 234.727 1.00 69.48  ? 141 SER A OG  1 
ATOM   879   N  N   . LYS A 1 142 ? 242.214 231.996 235.332 1.00 60.12  ? 142 LYS A N   1 
ATOM   880   C  CA  . LYS A 1 142 ? 240.796 231.725 235.125 1.00 66.67  ? 142 LYS A CA  1 
ATOM   881   C  C   . LYS A 1 142 ? 239.960 232.881 235.658 1.00 65.99  ? 142 LYS A C   1 
ATOM   882   O  O   . LYS A 1 142 ? 240.104 233.249 236.829 1.00 62.48  ? 142 LYS A O   1 
ATOM   883   C  CB  . LYS A 1 142 ? 240.386 230.424 235.800 1.00 66.61  ? 142 LYS A CB  1 
ATOM   884   C  CG  . LYS A 1 142 ? 240.808 230.291 237.246 1.00 64.34  ? 142 LYS A CG  1 
ATOM   885   C  CD  . LYS A 1 142 ? 240.095 229.115 237.883 1.00 63.51  ? 142 LYS A CD  1 
ATOM   886   C  CE  . LYS A 1 142 ? 238.647 229.053 237.422 1.00 63.77  ? 142 LYS A CE  1 
ATOM   887   N  NZ  . LYS A 1 142 ? 237.974 227.789 237.823 1.00 62.93  ? 142 LYS A NZ  1 
ATOM   888   N  N   . PRO A 1 143 ? 239.085 233.472 234.849 1.00 68.06  ? 143 PRO A N   1 
ATOM   889   C  CA  . PRO A 1 143 ? 238.333 234.647 235.303 1.00 67.77  ? 143 PRO A CA  1 
ATOM   890   C  C   . PRO A 1 143 ? 237.348 234.308 236.409 1.00 66.74  ? 143 PRO A C   1 
ATOM   891   O  O   . PRO A 1 143 ? 236.837 233.189 236.504 1.00 66.34  ? 143 PRO A O   1 
ATOM   892   C  CB  . PRO A 1 143 ? 237.606 235.112 234.037 1.00 64.63  ? 143 PRO A CB  1 
ATOM   893   C  CG  . PRO A 1 143 ? 237.500 233.886 233.196 1.00 66.04  ? 143 PRO A CG  1 
ATOM   894   C  CD  . PRO A 1 143 ? 238.729 233.076 233.476 1.00 62.04  ? 143 PRO A CD  1 
ATOM   895   N  N   . ILE A 1 144 ? 237.087 235.299 237.252 1.00 62.78  ? 144 ILE A N   1 
ATOM   896   C  CA  . ILE A 1 144 ? 236.093 235.141 238.319 1.00 60.57  ? 144 ILE A CA  1 
ATOM   897   C  C   . ILE A 1 144 ? 234.707 235.034 237.697 1.00 64.02  ? 144 ILE A C   1 
ATOM   898   O  O   . ILE A 1 144 ? 234.438 235.697 236.679 1.00 64.66  ? 144 ILE A O   1 
ATOM   899   C  CB  . ILE A 1 144 ? 236.172 236.317 239.296 1.00 60.00  ? 144 ILE A CB  1 
ATOM   900   C  CG1 . ILE A 1 144 ? 237.221 236.045 240.376 1.00 51.69  ? 144 ILE A CG1 1 
ATOM   901   C  CG2 . ILE A 1 144 ? 234.812 236.586 239.921 1.00 56.37  ? 144 ILE A CG2 1 
ATOM   902   C  CD1 . ILE A 1 144 ? 237.653 237.280 241.133 1.00 37.18  ? 144 ILE A CD1 1 
ATOM   903   N  N   . PRO A 1 145 ? 233.805 234.227 238.252 1.00 67.19  ? 145 PRO A N   1 
ATOM   904   C  CA  . PRO A 1 145 ? 232.476 234.089 237.645 1.00 68.12  ? 145 PRO A CA  1 
ATOM   905   C  C   . PRO A 1 145 ? 231.734 235.416 237.623 1.00 73.76  ? 145 PRO A C   1 
ATOM   906   O  O   . PRO A 1 145 ? 231.758 236.181 238.589 1.00 73.06  ? 145 PRO A O   1 
ATOM   907   C  CB  . PRO A 1 145 ? 231.772 233.066 238.548 1.00 69.57  ? 145 PRO A CB  1 
ATOM   908   C  CG  . PRO A 1 145 ? 232.847 232.468 239.404 1.00 67.16  ? 145 PRO A CG  1 
ATOM   909   C  CD  . PRO A 1 145 ? 233.917 233.494 239.522 1.00 66.87  ? 145 PRO A CD  1 
ATOM   910   N  N   . SER A 1 146 ? 231.064 235.683 236.506 1.00 80.53  ? 146 SER A N   1 
ATOM   911   C  CA  . SER A 1 146 ? 230.219 236.862 236.412 1.00 83.72  ? 146 SER A CA  1 
ATOM   912   C  C   . SER A 1 146 ? 229.008 236.712 237.324 1.00 84.94  ? 146 SER A C   1 
ATOM   913   O  O   . SER A 1 146 ? 228.500 235.610 237.542 1.00 85.26  ? 146 SER A O   1 
ATOM   914   C  CB  . SER A 1 146 ? 229.767 237.089 234.971 1.00 83.06  ? 146 SER A CB  1 
ATOM   915   O  OG  . SER A 1 146 ? 228.508 237.736 234.932 1.00 84.08  ? 146 SER A OG  1 
ATOM   916   N  N   . GLU A 1 147 ? 228.538 237.841 237.859 1.00 84.46  ? 147 GLU A N   1 
ATOM   917   C  CA  . GLU A 1 147 ? 227.435 237.791 238.812 1.00 85.10  ? 147 GLU A CA  1 
ATOM   918   C  C   . GLU A 1 147 ? 226.186 237.187 238.183 1.00 90.90  ? 147 GLU A C   1 
ATOM   919   O  O   . GLU A 1 147 ? 225.477 236.402 238.824 1.00 91.79  ? 147 GLU A O   1 
ATOM   920   C  CB  . GLU A 1 147 ? 227.151 239.189 239.359 1.00 86.94  ? 147 GLU A CB  1 
ATOM   921   C  CG  . GLU A 1 147 ? 228.295 239.766 240.178 1.00 84.24  ? 147 GLU A CG  1 
ATOM   922   C  CD  . GLU A 1 147 ? 227.929 241.065 240.865 1.00 79.15  ? 147 GLU A CD  1 
ATOM   923   O  OE1 . GLU A 1 147 ? 226.737 241.437 240.840 1.00 79.57  ? 147 GLU A OE1 1 
ATOM   924   O  OE2 . GLU A 1 147 ? 228.833 241.714 241.433 1.00 70.76  ? 147 GLU A OE2 1 
ATOM   925   N  N   . LYS A 1 148 ? 225.894 237.545 236.932 1.00 92.90  ? 148 LYS A N   1 
ATOM   926   C  CA  . LYS A 1 148 ? 224.752 236.959 236.240 1.00 92.59  ? 148 LYS A CA  1 
ATOM   927   C  C   . LYS A 1 148 ? 225.037 235.547 235.743 1.00 93.40  ? 148 LYS A C   1 
ATOM   928   O  O   . LYS A 1 148 ? 224.130 234.707 235.726 1.00 93.08  ? 148 LYS A O   1 
ATOM   929   C  CB  . LYS A 1 148 ? 224.332 237.848 235.069 1.00 99.77  ? 148 LYS A CB  1 
ATOM   930   C  CG  . LYS A 1 148 ? 225.366 237.943 233.958 1.00 100.39 ? 148 LYS A CG  1 
ATOM   931   C  CD  . LYS A 1 148 ? 224.836 238.739 232.777 1.00 100.00 ? 148 LYS A CD  1 
ATOM   932   C  CE  . LYS A 1 148 ? 223.497 238.198 232.302 1.00 102.60 ? 148 LYS A CE  1 
ATOM   933   N  NZ  . LYS A 1 148 ? 222.773 239.180 231.448 1.00 103.98 ? 148 LYS A NZ  1 
ATOM   934   N  N   . ARG A 1 149 ? 226.275 235.266 235.341 1.00 95.93  ? 149 ARG A N   1 
ATOM   935   C  CA  . ARG A 1 149 ? 226.640 233.994 234.731 1.00 97.20  ? 149 ARG A CA  1 
ATOM   936   C  C   . ARG A 1 149 ? 227.234 233.000 235.723 1.00 93.54  ? 149 ARG A C   1 
ATOM   937   O  O   . ARG A 1 149 ? 227.725 231.947 235.305 1.00 91.96  ? 149 ARG A O   1 
ATOM   938   C  CB  . ARG A 1 149 ? 227.626 234.231 233.584 1.00 97.74  ? 149 ARG A CB  1 
ATOM   939   C  CG  . ARG A 1 149 ? 226.972 234.469 232.234 1.00 101.55 ? 149 ARG A CG  1 
ATOM   940   C  CD  . ARG A 1 149 ? 226.558 233.161 231.584 1.00 105.12 ? 149 ARG A CD  1 
ATOM   941   N  NE  . ARG A 1 149 ? 227.465 232.071 231.924 1.00 108.21 ? 149 ARG A NE  1 
ATOM   942   C  CZ  . ARG A 1 149 ? 227.075 230.875 232.344 1.00 107.17 ? 149 ARG A CZ  1 
ATOM   943   N  NH1 . ARG A 1 149 ? 225.795 230.577 232.486 1.00 103.27 ? 149 ARG A NH1 1 
ATOM   944   N  NH2 . ARG A 1 149 ? 227.994 229.956 232.629 1.00 101.98 ? 149 ARG A NH2 1 
ATOM   945   N  N   . ALA A 1 150 ? 227.205 233.304 237.017 1.00 90.56  ? 150 ALA A N   1 
ATOM   946   C  CA  . ALA A 1 150 ? 227.830 232.455 238.019 1.00 86.18  ? 150 ALA A CA  1 
ATOM   947   C  C   . ALA A 1 150 ? 226.817 231.448 238.562 1.00 84.96  ? 150 ALA A C   1 
ATOM   948   O  O   . ALA A 1 150 ? 225.703 231.312 238.050 1.00 88.08  ? 150 ALA A O   1 
ATOM   949   C  CB  . ALA A 1 150 ? 228.433 233.306 239.133 1.00 79.18  ? 150 ALA A CB  1 
ATOM   950   N  N   . THR A 1 151 ? 227.204 230.725 239.608 1.00 83.35  ? 151 THR A N   1 
ATOM   951   C  CA  . THR A 1 151 ? 226.350 229.760 240.281 1.00 79.08  ? 151 THR A CA  1 
ATOM   952   C  C   . THR A 1 151 ? 226.012 230.264 241.682 1.00 76.61  ? 151 THR A C   1 
ATOM   953   O  O   . THR A 1 151 ? 226.414 231.355 242.090 1.00 80.68  ? 151 THR A O   1 
ATOM   954   C  CB  . THR A 1 151 ? 227.023 228.387 240.334 1.00 79.32  ? 151 THR A CB  1 
ATOM   955   O  OG1 . THR A 1 151 ? 226.023 227.363 240.396 1.00 84.42  ? 151 THR A OG1 1 
ATOM   956   C  CG2 . THR A 1 151 ? 227.924 228.280 241.552 1.00 80.43  ? 151 THR A CG2 1 
ATOM   957   N  N   . GLU A 1 152 ? 225.263 229.447 242.424 1.00 75.63  ? 152 GLU A N   1 
ATOM   958   C  CA  . GLU A 1 152 ? 224.810 229.857 243.751 1.00 80.41  ? 152 GLU A CA  1 
ATOM   959   C  C   . GLU A 1 152 ? 225.982 230.010 244.714 1.00 79.43  ? 152 GLU A C   1 
ATOM   960   O  O   . GLU A 1 152 ? 226.118 231.039 245.388 1.00 77.07  ? 152 GLU A O   1 
ATOM   961   C  CB  . GLU A 1 152 ? 223.797 228.847 244.287 1.00 85.79  ? 152 GLU A CB  1 
ATOM   962   C  CG  . GLU A 1 152 ? 222.953 229.358 245.441 1.00 86.85  ? 152 GLU A CG  1 
ATOM   963   C  CD  . GLU A 1 152 ? 223.342 228.733 246.764 1.00 93.61  ? 152 GLU A CD  1 
ATOM   964   O  OE1 . GLU A 1 152 ? 223.373 227.488 246.847 1.00 92.25  ? 152 GLU A OE1 1 
ATOM   965   O  OE2 . GLU A 1 152 ? 223.614 229.488 247.721 1.00 96.62  ? 152 GLU A OE2 1 
ATOM   966   N  N   . GLU A 1 153 ? 226.843 228.992 244.793 1.00 80.09  ? 153 GLU A N   1 
ATOM   967   C  CA  . GLU A 1 153 ? 227.998 229.071 245.681 1.00 77.59  ? 153 GLU A CA  1 
ATOM   968   C  C   . GLU A 1 153 ? 228.958 230.165 245.234 1.00 73.22  ? 153 GLU A C   1 
ATOM   969   O  O   . GLU A 1 153 ? 229.563 230.853 246.065 1.00 70.94  ? 153 GLU A O   1 
ATOM   970   C  CB  . GLU A 1 153 ? 228.705 227.718 245.743 1.00 81.55  ? 153 GLU A CB  1 
ATOM   971   C  CG  . GLU A 1 153 ? 228.047 226.726 246.687 1.00 87.72  ? 153 GLU A CG  1 
ATOM   972   C  CD  . GLU A 1 153 ? 226.888 225.990 246.043 1.00 94.00  ? 153 GLU A CD  1 
ATOM   973   O  OE1 . GLU A 1 153 ? 226.781 226.013 244.798 1.00 92.70  ? 153 GLU A OE1 1 
ATOM   974   O  OE2 . GLU A 1 153 ? 226.079 225.391 246.784 1.00 92.12  ? 153 GLU A OE2 1 
ATOM   975   N  N   . GLU A 1 154 ? 229.114 230.339 243.920 1.00 68.23  ? 154 GLU A N   1 
ATOM   976   C  CA  . GLU A 1 154 ? 229.920 231.444 243.417 1.00 68.12  ? 154 GLU A CA  1 
ATOM   977   C  C   . GLU A 1 154 ? 229.341 232.784 243.852 1.00 66.13  ? 154 GLU A C   1 
ATOM   978   O  O   . GLU A 1 154 ? 230.084 233.697 244.231 1.00 65.65  ? 154 GLU A O   1 
ATOM   979   C  CB  . GLU A 1 154 ? 230.019 231.371 241.894 1.00 73.55  ? 154 GLU A CB  1 
ATOM   980   C  CG  . GLU A 1 154 ? 230.609 230.074 241.370 1.00 74.75  ? 154 GLU A CG  1 
ATOM   981   C  CD  . GLU A 1 154 ? 230.759 230.073 239.862 1.00 83.00  ? 154 GLU A CD  1 
ATOM   982   O  OE1 . GLU A 1 154 ? 229.948 230.735 239.184 1.00 81.28  ? 154 GLU A OE1 1 
ATOM   983   O  OE2 . GLU A 1 154 ? 231.688 229.412 239.354 1.00 87.19  ? 154 GLU A OE2 1 
ATOM   984   N  N   . ILE A 1 155 ? 228.014 232.921 243.803 1.00 66.63  ? 155 ILE A N   1 
ATOM   985   C  CA  . ILE A 1 155 ? 227.381 234.163 244.234 1.00 63.99  ? 155 ILE A CA  1 
ATOM   986   C  C   . ILE A 1 155 ? 227.623 234.397 245.718 1.00 60.49  ? 155 ILE A C   1 
ATOM   987   O  O   . ILE A 1 155 ? 227.882 235.527 246.148 1.00 59.45  ? 155 ILE A O   1 
ATOM   988   C  CB  . ILE A 1 155 ? 225.878 234.146 243.900 1.00 70.19  ? 155 ILE A CB  1 
ATOM   989   C  CG1 . ILE A 1 155 ? 225.622 234.835 242.558 1.00 72.02  ? 155 ILE A CG1 1 
ATOM   990   C  CG2 . ILE A 1 155 ? 225.081 234.816 245.005 1.00 64.32  ? 155 ILE A CG2 1 
ATOM   991   C  CD1 . ILE A 1 155 ? 226.245 234.130 241.379 1.00 74.56  ? 155 ILE A CD1 1 
ATOM   992   N  N   . ALA A 1 156 ? 227.533 233.341 246.527 1.00 60.55  ? 156 ALA A N   1 
ATOM   993   C  CA  . ALA A 1 156 ? 227.816 233.486 247.952 1.00 58.41  ? 156 ALA A CA  1 
ATOM   994   C  C   . ALA A 1 156 ? 229.252 233.946 248.179 1.00 57.93  ? 156 ALA A C   1 
ATOM   995   O  O   . ALA A 1 156 ? 229.508 234.873 248.959 1.00 61.23  ? 156 ALA A O   1 
ATOM   996   C  CB  . ALA A 1 156 ? 227.549 232.167 248.677 1.00 59.49  ? 156 ALA A CB  1 
ATOM   997   N  N   . ALA A 1 157 ? 230.205 233.312 247.493 1.00 58.98  ? 157 ALA A N   1 
ATOM   998   C  CA  . ALA A 1 157 ? 231.606 233.683 247.661 1.00 53.54  ? 157 ALA A CA  1 
ATOM   999   C  C   . ALA A 1 157 ? 231.853 235.122 247.229 1.00 52.85  ? 157 ALA A C   1 
ATOM   1000  O  O   . ALA A 1 157 ? 232.638 235.840 247.858 1.00 54.88  ? 157 ALA A O   1 
ATOM   1001  C  CB  . ALA A 1 157 ? 232.502 232.727 246.874 1.00 52.73  ? 157 ALA A CB  1 
ATOM   1002  N  N   . ILE A 1 158 ? 231.200 235.559 246.153 1.00 53.36  ? 158 ILE A N   1 
ATOM   1003  C  CA  . ILE A 1 158 ? 231.381 236.930 245.685 1.00 48.05  ? 158 ILE A CA  1 
ATOM   1004  C  C   . ILE A 1 158 ? 230.783 237.918 246.680 1.00 47.65  ? 158 ILE A C   1 
ATOM   1005  O  O   . ILE A 1 158 ? 231.409 238.924 247.032 1.00 47.77  ? 158 ILE A O   1 
ATOM   1006  C  CB  . ILE A 1 158 ? 230.772 237.101 244.282 1.00 46.88  ? 158 ILE A CB  1 
ATOM   1007  C  CG1 . ILE A 1 158 ? 231.586 236.319 243.250 1.00 48.00  ? 158 ILE A CG1 1 
ATOM   1008  C  CG2 . ILE A 1 158 ? 230.710 238.572 243.910 1.00 45.06  ? 158 ILE A CG2 1 
ATOM   1009  C  CD1 . ILE A 1 158 ? 231.108 236.506 241.829 1.00 53.66  ? 158 ILE A CD1 1 
ATOM   1010  N  N   . ASN A 1 159 ? 229.563 237.648 247.149 1.00 49.54  ? 159 ASN A N   1 
ATOM   1011  C  CA  . ASN A 1 159 ? 228.896 238.555 248.075 1.00 48.25  ? 159 ASN A CA  1 
ATOM   1012  C  C   . ASN A 1 159 ? 229.546 238.570 249.450 1.00 44.95  ? 159 ASN A C   1 
ATOM   1013  O  O   . ASN A 1 159 ? 229.288 239.493 250.230 1.00 43.82  ? 159 ASN A O   1 
ATOM   1014  C  CB  . ASN A 1 159 ? 227.420 238.179 248.213 1.00 47.79  ? 159 ASN A CB  1 
ATOM   1015  C  CG  . ASN A 1 159 ? 226.662 238.297 246.908 1.00 55.65  ? 159 ASN A CG  1 
ATOM   1016  O  OD1 . ASN A 1 159 ? 227.171 238.839 245.927 1.00 58.92  ? 159 ASN A OD1 1 
ATOM   1017  N  ND2 . ASN A 1 159 ? 225.438 237.784 246.888 1.00 53.58  ? 159 ASN A ND2 1 
ATOM   1018  N  N   . SER A 1 160 ? 230.373 237.572 249.771 1.00 44.62  ? 160 SER A N   1 
ATOM   1019  C  CA  . SER A 1 160 ? 230.996 237.541 251.090 1.00 45.90  ? 160 SER A CA  1 
ATOM   1020  C  C   . SER A 1 160 ? 231.761 238.824 251.394 1.00 41.01  ? 160 SER A C   1 
ATOM   1021  O  O   . SER A 1 160 ? 231.839 239.235 252.557 1.00 43.02  ? 160 SER A O   1 
ATOM   1022  C  CB  . SER A 1 160 ? 231.927 236.333 251.203 1.00 48.71  ? 160 SER A CB  1 
ATOM   1023  O  OG  . SER A 1 160 ? 232.989 236.417 250.271 1.00 45.68  ? 160 SER A OG  1 
ATOM   1024  N  N   . VAL A 1 161 ? 232.327 239.475 250.372 1.00 38.03  ? 161 VAL A N   1 
ATOM   1025  C  CA  . VAL A 1 161 ? 233.137 240.671 250.597 1.00 36.95  ? 161 VAL A CA  1 
ATOM   1026  C  C   . VAL A 1 161 ? 232.340 241.964 250.500 1.00 33.55  ? 161 VAL A C   1 
ATOM   1027  O  O   . VAL A 1 161 ? 232.890 243.039 250.783 1.00 33.73  ? 161 VAL A O   1 
ATOM   1028  C  CB  . VAL A 1 161 ? 234.313 240.744 249.603 1.00 33.49  ? 161 VAL A CB  1 
ATOM   1029  C  CG1 . VAL A 1 161 ? 235.263 239.578 249.819 1.00 36.08  ? 161 VAL A CG1 1 
ATOM   1030  C  CG2 . VAL A 1 161 ? 233.801 240.774 248.174 1.00 34.85  ? 161 VAL A CG2 1 
ATOM   1031  N  N   . TYR A 1 162 ? 231.071 241.901 250.117 1.00 38.12  ? 162 TYR A N   1 
ATOM   1032  C  CA  . TYR A 1 162 ? 230.244 243.087 249.965 1.00 35.26  ? 162 TYR A CA  1 
ATOM   1033  C  C   . TYR A 1 162 ? 229.323 243.258 251.165 1.00 36.48  ? 162 TYR A C   1 
ATOM   1034  O  O   . TYR A 1 162 ? 228.972 242.292 251.847 1.00 40.65  ? 162 TYR A O   1 
ATOM   1035  C  CB  . TYR A 1 162 ? 229.412 243.013 248.685 1.00 35.05  ? 162 TYR A CB  1 
ATOM   1036  C  CG  . TYR A 1 162 ? 230.186 243.331 247.431 1.00 35.41  ? 162 TYR A CG  1 
ATOM   1037  C  CD1 . TYR A 1 162 ? 230.387 244.644 247.031 1.00 34.57  ? 162 TYR A CD1 1 
ATOM   1038  C  CD2 . TYR A 1 162 ? 230.719 242.319 246.648 1.00 38.00  ? 162 TYR A CD2 1 
ATOM   1039  C  CE1 . TYR A 1 162 ? 231.093 244.939 245.885 1.00 38.87  ? 162 TYR A CE1 1 
ATOM   1040  C  CE2 . TYR A 1 162 ? 231.428 242.606 245.499 1.00 37.34  ? 162 TYR A CE2 1 
ATOM   1041  C  CZ  . TYR A 1 162 ? 231.611 243.915 245.122 1.00 37.58  ? 162 TYR A CZ  1 
ATOM   1042  O  OH  . TYR A 1 162 ? 232.318 244.199 243.978 1.00 46.73  ? 162 TYR A OH  1 
ATOM   1043  N  N   . TYR A 1 163 ? 228.930 244.504 251.412 1.00 35.45  ? 163 TYR A N   1 
ATOM   1044  C  CA  . TYR A 1 163 ? 228.020 244.856 252.489 1.00 37.20  ? 163 TYR A CA  1 
ATOM   1045  C  C   . TYR A 1 163 ? 226.946 245.776 251.932 1.00 36.11  ? 163 TYR A C   1 
ATOM   1046  O  O   . TYR A 1 163 ? 227.251 246.718 251.193 1.00 39.78  ? 163 TYR A O   1 
ATOM   1047  C  CB  . TYR A 1 163 ? 228.772 245.527 253.644 1.00 37.20  ? 163 TYR A CB  1 
ATOM   1048  C  CG  . TYR A 1 163 ? 227.938 246.475 254.470 1.00 41.24  ? 163 TYR A CG  1 
ATOM   1049  C  CD1 . TYR A 1 163 ? 227.152 246.010 255.514 1.00 44.07  ? 163 TYR A CD1 1 
ATOM   1050  C  CD2 . TYR A 1 163 ? 227.954 247.840 254.220 1.00 42.95  ? 163 TYR A CD2 1 
ATOM   1051  C  CE1 . TYR A 1 163 ? 226.394 246.876 256.274 1.00 42.66  ? 163 TYR A CE1 1 
ATOM   1052  C  CE2 . TYR A 1 163 ? 227.201 248.712 254.975 1.00 38.53  ? 163 TYR A CE2 1 
ATOM   1053  C  CZ  . TYR A 1 163 ? 226.424 248.226 256.000 1.00 42.58  ? 163 TYR A CZ  1 
ATOM   1054  O  OH  . TYR A 1 163 ? 225.673 249.098 256.752 1.00 49.35  ? 163 TYR A OH  1 
ATOM   1055  N  N   . THR A 1 164 ? 225.695 245.491 252.273 1.00 38.44  ? 164 THR A N   1 
ATOM   1056  C  CA  . THR A 1 164 ? 224.550 246.263 251.812 1.00 42.04  ? 164 THR A CA  1 
ATOM   1057  C  C   . THR A 1 164 ? 223.915 246.980 252.993 1.00 45.61  ? 164 THR A C   1 
ATOM   1058  O  O   . THR A 1 164 ? 223.607 246.352 254.012 1.00 43.18  ? 164 THR A O   1 
ATOM   1059  C  CB  . THR A 1 164 ? 223.519 245.362 251.130 1.00 39.19  ? 164 THR A CB  1 
ATOM   1060  O  OG1 . THR A 1 164 ? 224.173 244.531 250.163 1.00 47.91  ? 164 THR A OG1 1 
ATOM   1061  C  CG2 . THR A 1 164 ? 222.458 246.197 250.435 1.00 41.55  ? 164 THR A CG2 1 
ATOM   1062  N  N   . ASN A 1 165 ? 223.724 248.283 252.858 1.00 42.09  ? 165 ASN A N   1 
ATOM   1063  C  CA  . ASN A 1 165 ? 223.047 249.045 253.896 1.00 39.90  ? 165 ASN A CA  1 
ATOM   1064  C  C   . ASN A 1 165 ? 221.590 248.610 253.961 1.00 40.07  ? 165 ASN A C   1 
ATOM   1065  O  O   . ASN A 1 165 ? 220.879 248.708 252.952 1.00 43.66  ? 165 ASN A O   1 
ATOM   1066  C  CB  . ASN A 1 165 ? 223.149 250.538 253.615 1.00 41.07  ? 165 ASN A CB  1 
ATOM   1067  C  CG  . ASN A 1 165 ? 222.827 251.382 254.829 1.00 41.86  ? 165 ASN A CG  1 
ATOM   1068  O  OD1 . ASN A 1 165 ? 221.736 251.293 255.390 1.00 45.07  ? 165 ASN A OD1 1 
ATOM   1069  N  ND2 . ASN A 1 165 ? 223.777 252.211 255.241 1.00 42.03  ? 165 ASN A ND2 1 
ATOM   1070  N  N   . PRO A 1 166 ? 221.103 248.127 255.105 1.00 38.96  ? 166 PRO A N   1 
ATOM   1071  C  CA  . PRO A 1 166 ? 219.715 247.647 255.163 1.00 39.27  ? 166 PRO A CA  1 
ATOM   1072  C  C   . PRO A 1 166 ? 218.684 248.738 254.938 1.00 43.85  ? 166 PRO A C   1 
ATOM   1073  O  O   . PRO A 1 166 ? 217.538 248.417 254.600 1.00 46.75  ? 166 PRO A O   1 
ATOM   1074  C  CB  . PRO A 1 166 ? 219.608 247.054 256.573 1.00 37.45  ? 166 PRO A CB  1 
ATOM   1075  C  CG  . PRO A 1 166 ? 220.644 247.771 257.361 1.00 38.97  ? 166 PRO A CG  1 
ATOM   1076  C  CD  . PRO A 1 166 ? 221.769 248.078 256.417 1.00 40.04  ? 166 PRO A CD  1 
ATOM   1077  N  N   . VAL A 1 167 ? 219.047 250.008 255.111 1.00 44.95  ? 167 VAL A N   1 
ATOM   1078  C  CA  . VAL A 1 167 ? 218.093 251.103 254.980 1.00 42.72  ? 167 VAL A CA  1 
ATOM   1079  C  C   . VAL A 1 167 ? 218.031 251.579 253.534 1.00 44.02  ? 167 VAL A C   1 
ATOM   1080  O  O   . VAL A 1 167 ? 216.984 251.481 252.885 1.00 49.60  ? 167 VAL A O   1 
ATOM   1081  C  CB  . VAL A 1 167 ? 218.453 252.266 255.922 1.00 39.67  ? 167 VAL A CB  1 
ATOM   1082  C  CG1 . VAL A 1 167 ? 217.616 253.493 255.595 1.00 32.70  ? 167 VAL A CG1 1 
ATOM   1083  C  CG2 . VAL A 1 167 ? 218.261 251.853 257.370 1.00 38.80  ? 167 VAL A CG2 1 
ATOM   1084  N  N   . THR A 1 168 ? 219.145 252.098 253.021 1.00 44.76  ? 168 THR A N   1 
ATOM   1085  C  CA  . THR A 1 168 ? 219.171 252.672 251.682 1.00 45.22  ? 168 THR A CA  1 
ATOM   1086  C  C   . THR A 1 168 ? 219.522 251.661 250.595 1.00 46.62  ? 168 THR A C   1 
ATOM   1087  O  O   . THR A 1 168 ? 219.360 251.972 249.411 1.00 49.15  ? 168 THR A O   1 
ATOM   1088  C  CB  . THR A 1 168 ? 220.148 253.852 251.630 1.00 47.25  ? 168 THR A CB  1 
ATOM   1089  O  OG1 . THR A 1 168 ? 221.460 253.383 251.311 1.00 45.19  ? 168 THR A OG1 1 
ATOM   1090  C  CG2 . THR A 1 168 ? 220.185 254.573 252.970 1.00 43.11  ? 168 THR A CG2 1 
ATOM   1091  N  N   . HIS A 1 169 ? 219.994 250.468 250.961 1.00 47.46  ? 169 HIS A N   1 
ATOM   1092  C  CA  . HIS A 1 169 ? 220.148 249.361 250.016 1.00 45.61  ? 169 HIS A CA  1 
ATOM   1093  C  C   . HIS A 1 169 ? 221.306 249.581 249.042 1.00 48.13  ? 169 HIS A C   1 
ATOM   1094  O  O   . HIS A 1 169 ? 221.221 249.205 247.873 1.00 50.06  ? 169 HIS A O   1 
ATOM   1095  C  CB  . HIS A 1 169 ? 218.849 249.116 249.243 1.00 44.61  ? 169 HIS A CB  1 
ATOM   1096  C  CG  . HIS A 1 169 ? 217.668 248.835 250.117 1.00 50.45  ? 169 HIS A CG  1 
ATOM   1097  N  ND1 . HIS A 1 169 ? 217.641 247.794 251.019 1.00 53.60  ? 169 HIS A ND1 1 
ATOM   1098  C  CD2 . HIS A 1 169 ? 216.471 249.458 250.225 1.00 53.04  ? 169 HIS A CD2 1 
ATOM   1099  C  CE1 . HIS A 1 169 ? 216.479 247.788 251.646 1.00 54.24  ? 169 HIS A CE1 1 
ATOM   1100  N  NE2 . HIS A 1 169 ? 215.751 248.788 251.184 1.00 53.27  ? 169 HIS A NE2 1 
ATOM   1101  N  N   . ASP A 1 170 ? 222.392 250.184 249.512 1.00 45.37  ? 170 ASP A N   1 
ATOM   1102  C  CA  . ASP A 1 170 ? 223.576 250.380 248.686 1.00 45.26  ? 170 ASP A CA  1 
ATOM   1103  C  C   . ASP A 1 170 ? 224.566 249.262 248.978 1.00 47.25  ? 170 ASP A C   1 
ATOM   1104  O  O   . ASP A 1 170 ? 224.857 248.974 250.143 1.00 47.99  ? 170 ASP A O   1 
ATOM   1105  C  CB  . ASP A 1 170 ? 224.235 251.743 248.929 1.00 48.87  ? 170 ASP A CB  1 
ATOM   1106  C  CG  . ASP A 1 170 ? 224.252 252.151 250.395 1.00 59.75  ? 170 ASP A CG  1 
ATOM   1107  O  OD1 . ASP A 1 170 ? 223.285 251.872 251.130 1.00 57.02  ? 170 ASP A OD1 1 
ATOM   1108  O  OD2 . ASP A 1 170 ? 225.253 252.771 250.814 1.00 64.31  ? 170 ASP A OD2 1 
ATOM   1109  N  N   . ARG A 1 171 ? 225.067 248.625 247.922 1.00 44.10  ? 171 ARG A N   1 
ATOM   1110  C  CA  . ARG A 1 171 ? 226.011 247.519 248.035 1.00 40.21  ? 171 ARG A CA  1 
ATOM   1111  C  C   . ARG A 1 171 ? 227.415 248.054 247.776 1.00 42.55  ? 171 ARG A C   1 
ATOM   1112  O  O   . ARG A 1 171 ? 227.746 248.420 246.643 1.00 47.17  ? 171 ARG A O   1 
ATOM   1113  C  CB  . ARG A 1 171 ? 225.652 246.407 247.050 1.00 39.36  ? 171 ARG A CB  1 
ATOM   1114  C  CG  . ARG A 1 171 ? 226.441 245.114 247.213 1.00 39.84  ? 171 ARG A CG  1 
ATOM   1115  C  CD  . ARG A 1 171 ? 225.763 243.978 246.456 1.00 42.98  ? 171 ARG A CD  1 
ATOM   1116  N  NE  . ARG A 1 171 ? 226.702 242.951 246.021 1.00 42.32  ? 171 ARG A NE  1 
ATOM   1117  C  CZ  . ARG A 1 171 ? 227.506 243.062 244.973 1.00 45.44  ? 171 ARG A CZ  1 
ATOM   1118  N  NH1 . ARG A 1 171 ? 227.515 244.151 244.221 1.00 43.74  ? 171 ARG A NH1 1 
ATOM   1119  N  NH2 . ARG A 1 171 ? 228.320 242.056 244.670 1.00 47.85  ? 171 ARG A NH2 1 
ATOM   1120  N  N   . LYS A 1 172 ? 228.239 248.095 248.819 1.00 39.74  ? 172 LYS A N   1 
ATOM   1121  C  CA  . LYS A 1 172 ? 229.603 248.591 248.712 1.00 35.89  ? 172 LYS A CA  1 
ATOM   1122  C  C   . LYS A 1 172 ? 230.565 247.571 249.302 1.00 37.50  ? 172 LYS A C   1 
ATOM   1123  O  O   . LYS A 1 172 ? 230.193 246.744 250.135 1.00 40.68  ? 172 LYS A O   1 
ATOM   1124  C  CB  . LYS A 1 172 ? 229.779 249.939 249.425 1.00 37.83  ? 172 LYS A CB  1 
ATOM   1125  C  CG  . LYS A 1 172 ? 228.795 251.013 248.999 1.00 49.41  ? 172 LYS A CG  1 
ATOM   1126  C  CD  . LYS A 1 172 ? 228.391 251.883 250.181 1.00 53.52  ? 172 LYS A CD  1 
ATOM   1127  C  CE  . LYS A 1 172 ? 229.475 252.891 250.531 1.00 53.61  ? 172 LYS A CE  1 
ATOM   1128  N  NZ  . LYS A 1 172 ? 229.496 253.200 251.990 1.00 52.30  ? 172 LYS A NZ  1 
ATOM   1129  N  N   . LEU A 1 173 ? 231.819 247.642 248.869 1.00 36.31  ? 173 LEU A N   1 
ATOM   1130  C  CA  . LEU A 1 173 ? 232.835 246.761 249.425 1.00 34.71  ? 173 LEU A CA  1 
ATOM   1131  C  C   . LEU A 1 173 ? 232.909 246.943 250.935 1.00 33.55  ? 173 LEU A C   1 
ATOM   1132  O  O   . LEU A 1 173 ? 232.954 248.070 251.434 1.00 38.60  ? 173 LEU A O   1 
ATOM   1133  C  CB  . LEU A 1 173 ? 234.194 247.048 248.790 1.00 35.85  ? 173 LEU A CB  1 
ATOM   1134  C  CG  . LEU A 1 173 ? 234.424 246.501 247.383 1.00 34.78  ? 173 LEU A CG  1 
ATOM   1135  C  CD1 . LEU A 1 173 ? 235.724 247.044 246.815 1.00 28.05  ? 173 LEU A CD1 1 
ATOM   1136  C  CD2 . LEU A 1 173 ? 234.425 244.983 247.390 1.00 27.74  ? 173 LEU A CD2 1 
ATOM   1137  N  N   . ASN A 1 174 ? 232.924 245.835 251.660 1.00 34.06  ? 174 ASN A N   1 
ATOM   1138  C  CA  . ASN A 1 174 ? 232.988 245.902 253.114 1.00 33.70  ? 174 ASN A CA  1 
ATOM   1139  C  C   . ASN A 1 174 ? 234.386 246.323 253.548 1.00 35.30  ? 174 ASN A C   1 
ATOM   1140  O  O   . ASN A 1 174 ? 235.351 245.594 253.285 1.00 34.73  ? 174 ASN A O   1 
ATOM   1141  C  CB  . ASN A 1 174 ? 232.628 244.550 253.721 1.00 36.45  ? 174 ASN A CB  1 
ATOM   1142  C  CG  . ASN A 1 174 ? 232.364 244.629 255.210 1.00 39.17  ? 174 ASN A CG  1 
ATOM   1143  O  OD1 . ASN A 1 174 ? 232.662 245.633 255.854 1.00 44.01  ? 174 ASN A OD1 1 
ATOM   1144  N  ND2 . ASN A 1 174 ? 231.803 243.563 255.766 1.00 36.72  ? 174 ASN A ND2 1 
ATOM   1145  N  N   . PRO A 1 175 ? 234.546 247.471 254.209 1.00 38.26  ? 175 PRO A N   1 
ATOM   1146  C  CA  . PRO A 1 175 ? 235.893 247.882 254.636 1.00 33.50  ? 175 PRO A CA  1 
ATOM   1147  C  C   . PRO A 1 175 ? 236.549 246.895 255.580 1.00 37.05  ? 175 PRO A C   1 
ATOM   1148  O  O   . PRO A 1 175 ? 237.777 246.744 255.551 1.00 37.41  ? 175 PRO A O   1 
ATOM   1149  C  CB  . PRO A 1 175 ? 235.646 249.238 255.313 1.00 33.58  ? 175 PRO A CB  1 
ATOM   1150  C  CG  . PRO A 1 175 ? 234.359 249.724 254.730 1.00 33.74  ? 175 PRO A CG  1 
ATOM   1151  C  CD  . PRO A 1 175 ? 233.533 248.495 254.513 1.00 36.99  ? 175 PRO A CD  1 
ATOM   1152  N  N   . ASP A 1 176 ? 235.767 246.217 256.421 1.00 36.35  ? 176 ASP A N   1 
ATOM   1153  C  CA  . ASP A 1 176 ? 236.316 245.241 257.351 1.00 38.58  ? 176 ASP A CA  1 
ATOM   1154  C  C   . ASP A 1 176 ? 236.849 243.998 256.653 1.00 42.16  ? 176 ASP A C   1 
ATOM   1155  O  O   . ASP A 1 176 ? 237.527 243.190 257.297 1.00 43.78  ? 176 ASP A O   1 
ATOM   1156  C  CB  . ASP A 1 176 ? 235.254 244.841 258.375 1.00 45.02  ? 176 ASP A CB  1 
ATOM   1157  C  CG  . ASP A 1 176 ? 235.104 245.859 259.487 1.00 57.88  ? 176 ASP A CG  1 
ATOM   1158  O  OD1 . ASP A 1 176 ? 234.362 245.580 260.451 1.00 61.09  ? 176 ASP A OD1 1 
ATOM   1159  O  OD2 . ASP A 1 176 ? 235.726 246.938 259.396 1.00 57.78  ? 176 ASP A OD2 1 
ATOM   1160  N  N   . GLN A 1 177 ? 236.559 243.825 255.363 1.00 39.00  ? 177 GLN A N   1 
ATOM   1161  C  CA  . GLN A 1 177 ? 237.024 242.667 254.614 1.00 33.40  ? 177 GLN A CA  1 
ATOM   1162  C  C   . GLN A 1 177 ? 238.170 242.985 253.666 1.00 30.59  ? 177 GLN A C   1 
ATOM   1163  O  O   . GLN A 1 177 ? 238.878 242.064 253.246 1.00 33.12  ? 177 GLN A O   1 
ATOM   1164  C  CB  . GLN A 1 177 ? 235.870 242.057 253.811 1.00 39.16  ? 177 GLN A CB  1 
ATOM   1165  C  CG  . GLN A 1 177 ? 234.661 241.692 254.649 1.00 38.63  ? 177 GLN A CG  1 
ATOM   1166  C  CD  . GLN A 1 177 ? 234.773 240.314 255.261 1.00 43.07  ? 177 GLN A CD  1 
ATOM   1167  O  OE1 . GLN A 1 177 ? 234.932 239.322 254.554 1.00 45.82  ? 177 GLN A OE1 1 
ATOM   1168  N  NE2 . GLN A 1 177 ? 234.693 240.245 256.584 1.00 46.47  ? 177 GLN A NE2 1 
ATOM   1169  N  N   . MET A 1 178 ? 238.368 244.257 253.320 1.00 30.13  ? 178 MET A N   1 
ATOM   1170  C  CA  . MET A 1 178 ? 239.448 244.667 252.423 1.00 27.35  ? 178 MET A CA  1 
ATOM   1171  C  C   . MET A 1 178 ? 240.730 244.795 253.239 1.00 27.83  ? 178 MET A C   1 
ATOM   1172  O  O   . MET A 1 178 ? 241.162 245.884 253.626 1.00 28.13  ? 178 MET A O   1 
ATOM   1173  C  CB  . MET A 1 178 ? 239.096 245.970 251.717 1.00 29.70  ? 178 MET A CB  1 
ATOM   1174  C  CG  . MET A 1 178 ? 237.775 245.949 250.966 1.00 30.95  ? 178 MET A CG  1 
ATOM   1175  S  SD  . MET A 1 178 ? 237.810 244.952 249.463 1.00 39.34  ? 178 MET A SD  1 
ATOM   1176  C  CE  . MET A 1 178 ? 237.774 243.295 250.138 1.00 26.60  ? 178 MET A CE  1 
ATOM   1177  N  N   . VAL A 1 179 ? 241.349 243.649 253.508 1.00 29.25  ? 179 VAL A N   1 
ATOM   1178  C  CA  . VAL A 1 179 ? 242.570 243.576 254.300 1.00 28.22  ? 179 VAL A CA  1 
ATOM   1179  C  C   . VAL A 1 179 ? 243.669 242.962 253.445 1.00 25.11  ? 179 VAL A C   1 
ATOM   1180  O  O   . VAL A 1 179 ? 243.460 241.929 252.799 1.00 30.42  ? 179 VAL A O   1 
ATOM   1181  C  CB  . VAL A 1 179 ? 242.362 242.771 255.596 1.00 26.85  ? 179 VAL A CB  1 
ATOM   1182  C  CG1 . VAL A 1 179 ? 241.370 243.479 256.500 1.00 26.23  ? 179 VAL A CG1 1 
ATOM   1183  C  CG2 . VAL A 1 179 ? 241.875 241.374 255.277 1.00 31.63  ? 179 VAL A CG2 1 
ATOM   1184  N  N   . TYR A 1 180 ? 244.832 243.605 253.439 1.00 24.38  ? 180 TYR A N   1 
ATOM   1185  C  CA  . TYR A 1 180 ? 245.997 243.162 252.688 1.00 22.92  ? 180 TYR A CA  1 
ATOM   1186  C  C   . TYR A 1 180 ? 247.038 242.611 253.652 1.00 24.37  ? 180 TYR A C   1 
ATOM   1187  O  O   . TYR A 1 180 ? 247.338 243.239 254.672 1.00 24.04  ? 180 TYR A O   1 
ATOM   1188  C  CB  . TYR A 1 180 ? 246.581 244.318 251.874 1.00 21.89  ? 180 TYR A CB  1 
ATOM   1189  C  CG  . TYR A 1 180 ? 247.728 243.936 250.971 1.00 22.51  ? 180 TYR A CG  1 
ATOM   1190  C  CD1 . TYR A 1 180 ? 247.554 243.027 249.938 1.00 23.56  ? 180 TYR A CD1 1 
ATOM   1191  C  CD2 . TYR A 1 180 ? 248.985 244.498 251.143 1.00 22.00  ? 180 TYR A CD2 1 
ATOM   1192  C  CE1 . TYR A 1 180 ? 248.599 242.683 249.109 1.00 23.38  ? 180 TYR A CE1 1 
ATOM   1193  C  CE2 . TYR A 1 180 ? 250.035 244.160 250.318 1.00 20.00  ? 180 TYR A CE2 1 
ATOM   1194  C  CZ  . TYR A 1 180 ? 249.837 243.252 249.304 1.00 23.78  ? 180 TYR A CZ  1 
ATOM   1195  O  OH  . TYR A 1 180 ? 250.883 242.912 248.479 1.00 31.27  ? 180 TYR A OH  1 
ATOM   1196  N  N   . ARG A 1 181 ? 247.575 241.437 253.330 1.00 27.16  ? 181 ARG A N   1 
ATOM   1197  C  CA  . ARG A 1 181 ? 248.616 240.790 254.115 1.00 26.78  ? 181 ARG A CA  1 
ATOM   1198  C  C   . ARG A 1 181 ? 249.950 240.905 253.391 1.00 29.47  ? 181 ARG A C   1 
ATOM   1199  O  O   . ARG A 1 181 ? 250.024 240.703 252.175 1.00 30.39  ? 181 ARG A O   1 
ATOM   1200  C  CB  . ARG A 1 181 ? 248.286 239.315 254.356 1.00 27.84  ? 181 ARG A CB  1 
ATOM   1201  C  CG  . ARG A 1 181 ? 249.194 238.639 255.368 1.00 31.40  ? 181 ARG A CG  1 
ATOM   1202  C  CD  . ARG A 1 181 ? 249.407 237.172 255.034 1.00 34.80  ? 181 ARG A CD  1 
ATOM   1203  N  NE  . ARG A 1 181 ? 250.056 236.992 253.739 1.00 41.59  ? 181 ARG A NE  1 
ATOM   1204  C  CZ  . ARG A 1 181 ? 251.358 237.125 253.525 1.00 43.59  ? 181 ARG A CZ  1 
ATOM   1205  N  NH1 . ARG A 1 181 ? 252.194 237.427 254.504 1.00 42.21  ? 181 ARG A NH1 1 
ATOM   1206  N  NH2 . ARG A 1 181 ? 251.834 236.949 252.296 1.00 43.40  ? 181 ARG A NH2 1 
ATOM   1207  N  N   . TYR A 1 182 ? 251.002 241.233 254.137 1.00 28.37  ? 182 TYR A N   1 
ATOM   1208  C  CA  . TYR A 1 182 ? 252.307 241.378 253.507 1.00 26.89  ? 182 TYR A CA  1 
ATOM   1209  C  C   . TYR A 1 182 ? 253.411 241.357 254.555 1.00 27.40  ? 182 TYR A C   1 
ATOM   1210  O  O   . TYR A 1 182 ? 253.215 241.773 255.700 1.00 29.66  ? 182 TYR A O   1 
ATOM   1211  C  CB  . TYR A 1 182 ? 252.378 242.661 252.670 1.00 26.55  ? 182 TYR A CB  1 
ATOM   1212  C  CG  . TYR A 1 182 ? 252.552 243.930 253.471 1.00 26.33  ? 182 TYR A CG  1 
ATOM   1213  C  CD1 . TYR A 1 182 ? 251.478 244.512 254.131 1.00 21.70  ? 182 TYR A CD1 1 
ATOM   1214  C  CD2 . TYR A 1 182 ? 253.790 244.550 253.564 1.00 23.54  ? 182 TYR A CD2 1 
ATOM   1215  C  CE1 . TYR A 1 182 ? 251.633 245.671 254.860 1.00 19.81  ? 182 TYR A CE1 1 
ATOM   1216  C  CE2 . TYR A 1 182 ? 253.954 245.708 254.291 1.00 22.45  ? 182 TYR A CE2 1 
ATOM   1217  C  CZ  . TYR A 1 182 ? 252.872 246.264 254.937 1.00 22.54  ? 182 TYR A CZ  1 
ATOM   1218  O  OH  . TYR A 1 182 ? 253.031 247.420 255.663 1.00 25.17  ? 182 TYR A OH  1 
ATOM   1219  N  N   . GLU A 1 183 ? 254.582 240.882 254.136 1.00 31.87  ? 183 GLU A N   1 
ATOM   1220  C  CA  . GLU A 1 183 ? 255.757 240.786 254.987 1.00 29.61  ? 183 GLU A CA  1 
ATOM   1221  C  C   . GLU A 1 183 ? 256.865 241.680 254.450 1.00 27.04  ? 183 GLU A C   1 
ATOM   1222  O  O   . GLU A 1 183 ? 256.973 241.908 253.242 1.00 31.50  ? 183 GLU A O   1 
ATOM   1223  C  CB  . GLU A 1 183 ? 256.274 239.348 255.075 1.00 31.88  ? 183 GLU A CB  1 
ATOM   1224  C  CG  . GLU A 1 183 ? 255.212 238.306 255.337 1.00 38.64  ? 183 GLU A CG  1 
ATOM   1225  C  CD  . GLU A 1 183 ? 255.696 236.910 255.010 1.00 50.32  ? 183 GLU A CD  1 
ATOM   1226  O  OE1 . GLU A 1 183 ? 256.599 236.783 254.158 1.00 50.71  ? 183 GLU A OE1 1 
ATOM   1227  O  OE2 . GLU A 1 183 ? 255.183 235.941 255.607 1.00 52.57  ? 183 GLU A OE2 1 
ATOM   1228  N  N   . VAL A 1 184 ? 257.688 242.184 255.364 1.00 26.55  ? 184 VAL A N   1 
ATOM   1229  C  CA  . VAL A 1 184 ? 258.847 242.999 255.025 1.00 26.02  ? 184 VAL A CA  1 
ATOM   1230  C  C   . VAL A 1 184 ? 260.039 242.496 255.825 1.00 29.30  ? 184 VAL A C   1 
ATOM   1231  O  O   . VAL A 1 184 ? 259.933 242.284 257.037 1.00 29.23  ? 184 VAL A O   1 
ATOM   1232  C  CB  . VAL A 1 184 ? 258.605 244.494 255.304 1.00 29.58  ? 184 VAL A CB  1 
ATOM   1233  C  CG1 . VAL A 1 184 ? 259.552 245.343 254.473 1.00 30.61  ? 184 VAL A CG1 1 
ATOM   1234  C  CG2 . VAL A 1 184 ? 257.160 244.863 255.019 1.00 30.55  ? 184 VAL A CG2 1 
ATOM   1235  N  N   . TYR A 1 185 ? 261.169 242.313 255.153 1.00 31.80  ? 185 TYR A N   1 
ATOM   1236  C  CA  . TYR A 1 185 ? 262.396 241.902 255.818 1.00 29.00  ? 185 TYR A CA  1 
ATOM   1237  C  C   . TYR A 1 185 ? 263.225 243.133 256.158 1.00 27.93  ? 185 TYR A C   1 
ATOM   1238  O  O   . TYR A 1 185 ? 263.523 243.949 255.280 1.00 33.21  ? 185 TYR A O   1 
ATOM   1239  C  CB  . TYR A 1 185 ? 263.195 240.947 254.935 1.00 28.90  ? 185 TYR A CB  1 
ATOM   1240  C  CG  . TYR A 1 185 ? 264.370 240.318 255.640 1.00 32.47  ? 185 TYR A CG  1 
ATOM   1241  C  CD1 . TYR A 1 185 ? 264.202 239.205 256.450 1.00 31.44  ? 185 TYR A CD1 1 
ATOM   1242  C  CD2 . TYR A 1 185 ? 265.648 240.838 255.499 1.00 31.80  ? 185 TYR A CD2 1 
ATOM   1243  C  CE1 . TYR A 1 185 ? 265.271 238.629 257.098 1.00 30.46  ? 185 TYR A CE1 1 
ATOM   1244  C  CE2 . TYR A 1 185 ? 266.722 240.268 256.142 1.00 29.08  ? 185 TYR A CE2 1 
ATOM   1245  C  CZ  . TYR A 1 185 ? 266.529 239.164 256.939 1.00 34.20  ? 185 TYR A CZ  1 
ATOM   1246  O  OH  . TYR A 1 185 ? 267.600 238.593 257.582 1.00 42.60  ? 185 TYR A OH  1 
ATOM   1247  N  N   . ASP A 1 186 ? 263.586 243.268 257.432 1.00 28.96  ? 186 ASP A N   1 
ATOM   1248  C  CA  . ASP A 1 186 ? 264.363 244.411 257.912 1.00 28.62  ? 186 ASP A CA  1 
ATOM   1249  C  C   . ASP A 1 186 ? 265.836 244.160 257.615 1.00 30.15  ? 186 ASP A C   1 
ATOM   1250  O  O   . ASP A 1 186 ? 266.570 243.593 258.424 1.00 32.28  ? 186 ASP A O   1 
ATOM   1251  C  CB  . ASP A 1 186 ? 264.124 244.637 259.399 1.00 27.88  ? 186 ASP A CB  1 
ATOM   1252  C  CG  . ASP A 1 186 ? 264.514 246.031 259.850 1.00 36.96  ? 186 ASP A CG  1 
ATOM   1253  O  OD1 . ASP A 1 186 ? 265.191 246.743 259.080 1.00 36.90  ? 186 ASP A OD1 1 
ATOM   1254  O  OD2 . ASP A 1 186 ? 264.144 246.414 260.978 1.00 38.76  ? 186 ASP A OD2 1 
ATOM   1255  N  N   . TYR A 1 187 ? 266.274 244.593 256.432 1.00 29.32  ? 187 TYR A N   1 
ATOM   1256  C  CA  . TYR A 1 187 ? 267.669 244.405 256.046 1.00 27.50  ? 187 TYR A CA  1 
ATOM   1257  C  C   . TYR A 1 187 ? 268.608 245.213 256.931 1.00 28.29  ? 187 TYR A C   1 
ATOM   1258  O  O   . TYR A 1 187 ? 269.683 244.731 257.306 1.00 34.41  ? 187 TYR A O   1 
ATOM   1259  C  CB  . TYR A 1 187 ? 267.863 244.785 254.580 1.00 28.96  ? 187 TYR A CB  1 
ATOM   1260  C  CG  . TYR A 1 187 ? 267.279 243.793 253.607 1.00 30.11  ? 187 TYR A CG  1 
ATOM   1261  C  CD1 . TYR A 1 187 ? 267.989 242.661 253.230 1.00 30.91  ? 187 TYR A CD1 1 
ATOM   1262  C  CD2 . TYR A 1 187 ? 266.018 243.985 253.064 1.00 28.43  ? 187 TYR A CD2 1 
ATOM   1263  C  CE1 . TYR A 1 187 ? 267.459 241.751 252.340 1.00 31.78  ? 187 TYR A CE1 1 
ATOM   1264  C  CE2 . TYR A 1 187 ? 265.481 243.081 252.174 1.00 28.54  ? 187 TYR A CE2 1 
ATOM   1265  C  CZ  . TYR A 1 187 ? 266.204 241.966 251.816 1.00 32.45  ? 187 TYR A CZ  1 
ATOM   1266  O  OH  . TYR A 1 187 ? 265.667 241.064 250.928 1.00 36.55  ? 187 TYR A OH  1 
ATOM   1267  N  N   . ARG A 1 188 ? 268.230 246.447 257.266 1.00 28.26  ? 188 ARG A N   1 
ATOM   1268  C  CA  . ARG A 1 188 ? 269.117 247.297 258.052 1.00 26.82  ? 188 ARG A CA  1 
ATOM   1269  C  C   . ARG A 1 188 ? 269.306 246.756 259.462 1.00 31.32  ? 188 ARG A C   1 
ATOM   1270  O  O   . ARG A 1 188 ? 270.417 246.794 260.002 1.00 33.57  ? 188 ARG A O   1 
ATOM   1271  C  CB  . ARG A 1 188 ? 268.580 248.725 258.095 1.00 26.25  ? 188 ARG A CB  1 
ATOM   1272  C  CG  . ARG A 1 188 ? 269.652 249.752 258.378 1.00 32.03  ? 188 ARG A CG  1 
ATOM   1273  C  CD  . ARG A 1 188 ? 269.066 251.122 258.634 1.00 33.89  ? 188 ARG A CD  1 
ATOM   1274  N  NE  . ARG A 1 188 ? 270.040 252.005 259.263 1.00 43.09  ? 188 ARG A NE  1 
ATOM   1275  C  CZ  . ARG A 1 188 ? 271.157 252.426 258.684 1.00 35.77  ? 188 ARG A CZ  1 
ATOM   1276  N  NH1 . ARG A 1 188 ? 271.473 252.069 257.451 1.00 33.26  ? 188 ARG A NH1 1 
ATOM   1277  N  NH2 . ARG A 1 188 ? 271.976 253.224 259.361 1.00 30.40  ? 188 ARG A NH2 1 
ATOM   1278  N  N   . SER A 1 189 ? 268.234 246.258 260.079 1.00 28.89  ? 189 SER A N   1 
ATOM   1279  C  CA  . SER A 1 189 ? 268.357 245.697 261.419 1.00 28.17  ? 189 SER A CA  1 
ATOM   1280  C  C   . SER A 1 189 ? 269.141 244.393 261.406 1.00 30.23  ? 189 SER A C   1 
ATOM   1281  O  O   . SER A 1 189 ? 269.874 244.101 262.356 1.00 33.47  ? 189 SER A O   1 
ATOM   1282  C  CB  . SER A 1 189 ? 266.972 245.483 262.027 1.00 30.33  ? 189 SER A CB  1 
ATOM   1283  O  OG  . SER A 1 189 ? 267.067 244.988 263.349 1.00 31.81  ? 189 SER A OG  1 
ATOM   1284  N  N   . ALA A 1 190 ? 269.000 243.599 260.342 1.00 27.06  ? 190 ALA A N   1 
ATOM   1285  C  CA  . ALA A 1 190 ? 269.756 242.356 260.241 1.00 26.86  ? 190 ALA A CA  1 
ATOM   1286  C  C   . ALA A 1 190 ? 271.242 242.616 260.034 1.00 30.45  ? 190 ALA A C   1 
ATOM   1287  O  O   . ALA A 1 190 ? 272.074 241.803 260.448 1.00 33.79  ? 190 ALA A O   1 
ATOM   1288  C  CB  . ALA A 1 190 ? 269.203 241.498 259.105 1.00 25.51  ? 190 ALA A CB  1 
ATOM   1289  N  N   . ALA A 1 191 ? 271.592 243.734 259.401 1.00 29.51  ? 191 ALA A N   1 
ATOM   1290  C  CA  . ALA A 1 191 ? 272.983 244.072 259.129 1.00 27.73  ? 191 ALA A CA  1 
ATOM   1291  C  C   . ALA A 1 191 ? 273.678 244.741 260.308 1.00 29.40  ? 191 ALA A C   1 
ATOM   1292  O  O   . ALA A 1 191 ? 274.884 244.993 260.229 1.00 34.61  ? 191 ALA A O   1 
ATOM   1293  C  CB  . ALA A 1 191 ? 273.072 244.981 257.901 1.00 25.10  ? 191 ALA A CB  1 
ATOM   1294  N  N   . LEU A 1 192 ? 272.959 245.035 261.387 1.00 28.82  ? 192 LEU A N   1 
ATOM   1295  C  CA  . LEU A 1 192 ? 273.573 245.695 262.530 1.00 28.69  ? 192 LEU A CA  1 
ATOM   1296  C  C   . LEU A 1 192 ? 274.629 244.800 263.163 1.00 32.42  ? 192 LEU A C   1 
ATOM   1297  O  O   . LEU A 1 192 ? 274.471 243.579 263.238 1.00 37.14  ? 192 LEU A O   1 
ATOM   1298  C  CB  . LEU A 1 192 ? 272.511 246.065 263.563 1.00 31.84  ? 192 LEU A CB  1 
ATOM   1299  C  CG  . LEU A 1 192 ? 271.783 247.388 263.335 1.00 38.96  ? 192 LEU A CG  1 
ATOM   1300  C  CD1 . LEU A 1 192 ? 270.768 247.635 264.438 1.00 40.45  ? 192 LEU A CD1 1 
ATOM   1301  C  CD2 . LEU A 1 192 ? 272.776 248.535 263.245 1.00 36.91  ? 192 LEU A CD2 1 
ATOM   1302  N  N   . ARG A 1 193 ? 275.716 245.419 263.627 1.00 35.34  ? 193 ARG A N   1 
ATOM   1303  C  CA  . ARG A 1 193 ? 276.794 244.654 264.241 1.00 33.29  ? 193 ARG A CA  1 
ATOM   1304  C  C   . ARG A 1 193 ? 276.315 243.942 265.499 1.00 34.64  ? 193 ARG A C   1 
ATOM   1305  O  O   . ARG A 1 193 ? 276.708 242.800 265.763 1.00 35.99  ? 193 ARG A O   1 
ATOM   1306  C  CB  . ARG A 1 193 ? 277.974 245.574 264.553 1.00 31.61  ? 193 ARG A CB  1 
ATOM   1307  C  CG  . ARG A 1 193 ? 279.004 244.973 265.490 1.00 33.35  ? 193 ARG A CG  1 
ATOM   1308  C  CD  . ARG A 1 193 ? 279.876 243.944 264.785 1.00 28.80  ? 193 ARG A CD  1 
ATOM   1309  N  NE  . ARG A 1 193 ? 280.333 244.408 263.481 1.00 28.64  ? 193 ARG A NE  1 
ATOM   1310  C  CZ  . ARG A 1 193 ? 280.858 243.626 262.549 1.00 31.64  ? 193 ARG A CZ  1 
ATOM   1311  N  NH1 . ARG A 1 193 ? 281.016 242.328 262.745 1.00 34.62  ? 193 ARG A NH1 1 
ATOM   1312  N  NH2 . ARG A 1 193 ? 281.235 244.159 261.392 1.00 28.19  ? 193 ARG A NH2 1 
ATOM   1313  N  N   . GLU A 1 194 ? 275.466 244.601 266.290 1.00 36.54  ? 194 GLU A N   1 
ATOM   1314  C  CA  . GLU A 1 194 ? 274.959 243.999 267.516 1.00 35.29  ? 194 GLU A CA  1 
ATOM   1315  C  C   . GLU A 1 194 ? 273.972 242.871 267.249 1.00 36.00  ? 194 GLU A C   1 
ATOM   1316  O  O   . GLU A 1 194 ? 273.702 242.077 268.155 1.00 33.93  ? 194 GLU A O   1 
ATOM   1317  C  CB  . GLU A 1 194 ? 274.293 245.058 268.401 1.00 38.54  ? 194 GLU A CB  1 
ATOM   1318  C  CG  . GLU A 1 194 ? 275.192 246.220 268.821 1.00 51.24  ? 194 GLU A CG  1 
ATOM   1319  C  CD  . GLU A 1 194 ? 275.536 247.166 267.684 1.00 61.85  ? 194 GLU A CD  1 
ATOM   1320  O  OE1 . GLU A 1 194 ? 276.499 247.947 267.834 1.00 60.55  ? 194 GLU A OE1 1 
ATOM   1321  O  OE2 . GLU A 1 194 ? 274.834 247.146 266.651 1.00 56.88  ? 194 GLU A OE2 1 
ATOM   1322  N  N   . HIS A 1 195 ? 273.434 242.778 266.034 1.00 39.27  ? 195 HIS A N   1 
ATOM   1323  C  CA  . HIS A 1 195 ? 272.434 241.777 265.692 1.00 32.59  ? 195 HIS A CA  1 
ATOM   1324  C  C   . HIS A 1 195 ? 273.022 240.596 264.932 1.00 34.81  ? 195 HIS A C   1 
ATOM   1325  O  O   . HIS A 1 195 ? 272.276 239.844 264.296 1.00 39.18  ? 195 HIS A O   1 
ATOM   1326  C  CB  . HIS A 1 195 ? 271.305 242.413 264.883 1.00 30.56  ? 195 HIS A CB  1 
ATOM   1327  C  CG  . HIS A 1 195 ? 270.397 243.282 265.695 1.00 31.67  ? 195 HIS A CG  1 
ATOM   1328  N  ND1 . HIS A 1 195 ? 269.503 244.161 265.125 1.00 32.12  ? 195 HIS A ND1 1 
ATOM   1329  C  CD2 . HIS A 1 195 ? 270.244 243.404 267.034 1.00 30.37  ? 195 HIS A CD2 1 
ATOM   1330  C  CE1 . HIS A 1 195 ? 268.840 244.790 266.078 1.00 31.26  ? 195 HIS A CE1 1 
ATOM   1331  N  NE2 . HIS A 1 195 ? 269.270 244.349 267.246 1.00 32.34  ? 195 HIS A NE2 1 
ATOM   1332  N  N   . GLN A 1 196 ? 274.339 240.420 264.976 1.00 36.20  ? 196 GLN A N   1 
ATOM   1333  C  CA  . GLN A 1 196 ? 274.949 239.261 264.342 1.00 36.46  ? 196 GLN A CA  1 
ATOM   1334  C  C   . GLN A 1 196 ? 274.468 237.983 265.016 1.00 38.41  ? 196 GLN A C   1 
ATOM   1335  O  O   . GLN A 1 196 ? 274.417 237.890 266.244 1.00 39.87  ? 196 GLN A O   1 
ATOM   1336  C  CB  . GLN A 1 196 ? 276.473 239.356 264.413 1.00 37.80  ? 196 GLN A CB  1 
ATOM   1337  C  CG  . GLN A 1 196 ? 277.070 240.435 263.529 1.00 39.21  ? 196 GLN A CG  1 
ATOM   1338  C  CD  . GLN A 1 196 ? 277.605 239.888 262.220 1.00 53.36  ? 196 GLN A CD  1 
ATOM   1339  O  OE1 . GLN A 1 196 ? 277.676 238.676 262.022 1.00 57.52  ? 196 GLN A OE1 1 
ATOM   1340  N  NE2 . GLN A 1 196 ? 277.986 240.784 261.318 1.00 49.28  ? 196 GLN A NE2 1 
ATOM   1341  N  N   . LEU A 1 197 ? 274.110 236.990 264.201 1.00 39.24  ? 197 LEU A N   1 
ATOM   1342  C  CA  . LEU A 1 197 ? 273.598 235.740 264.747 1.00 38.19  ? 197 LEU A CA  1 
ATOM   1343  C  C   . LEU A 1 197 ? 274.659 234.966 265.518 1.00 39.53  ? 197 LEU A C   1 
ATOM   1344  O  O   . LEU A 1 197 ? 274.311 234.064 266.286 1.00 44.82  ? 197 LEU A O   1 
ATOM   1345  C  CB  . LEU A 1 197 ? 273.020 234.873 263.628 1.00 41.94  ? 197 LEU A CB  1 
ATOM   1346  C  CG  . LEU A 1 197 ? 271.671 235.340 263.077 1.00 40.08  ? 197 LEU A CG  1 
ATOM   1347  C  CD1 . LEU A 1 197 ? 271.053 234.274 262.189 1.00 37.27  ? 197 LEU A CD1 1 
ATOM   1348  C  CD2 . LEU A 1 197 ? 270.731 235.707 264.213 1.00 36.10  ? 197 LEU A CD2 1 
ATOM   1349  N  N   . LYS A 1 198 ? 275.933 235.293 265.333 1.00 41.85  ? 198 LYS A N   1 
ATOM   1350  C  CA  . LYS A 1 198 ? 277.025 234.700 266.092 1.00 40.23  ? 198 LYS A CA  1 
ATOM   1351  C  C   . LYS A 1 198 ? 277.551 235.727 267.083 1.00 43.77  ? 198 LYS A C   1 
ATOM   1352  O  O   . LYS A 1 198 ? 277.910 236.843 266.694 1.00 47.69  ? 198 LYS A O   1 
ATOM   1353  C  CB  . LYS A 1 198 ? 278.149 234.231 265.167 1.00 43.22  ? 198 LYS A CB  1 
ATOM   1354  C  CG  . LYS A 1 198 ? 277.898 232.886 264.511 1.00 46.88  ? 198 LYS A CG  1 
ATOM   1355  C  CD  . LYS A 1 198 ? 278.964 232.575 263.474 1.00 52.37  ? 198 LYS A CD  1 
ATOM   1356  C  CE  . LYS A 1 198 ? 279.044 231.085 263.196 1.00 57.21  ? 198 LYS A CE  1 
ATOM   1357  N  NZ  . LYS A 1 198 ? 277.770 230.394 263.532 1.00 55.26  ? 198 LYS A NZ  1 
ATOM   1358  N  N   . ALA A 1 199 ? 277.601 235.346 268.361 1.00 40.70  ? 199 ALA A N   1 
ATOM   1359  C  CA  . ALA A 1 199 ? 278.011 236.290 269.396 1.00 40.31  ? 199 ALA A CA  1 
ATOM   1360  C  C   . ALA A 1 199 ? 279.444 236.761 269.183 1.00 44.71  ? 199 ALA A C   1 
ATOM   1361  O  O   . ALA A 1 199 ? 279.753 237.943 269.374 1.00 42.53  ? 199 ALA A O   1 
ATOM   1362  C  CB  . ALA A 1 199 ? 277.854 235.655 270.777 1.00 40.65  ? 199 ALA A CB  1 
ATOM   1363  N  N   . ALA A 1 200 ? 280.334 235.850 268.784 1.00 49.29  ? 200 ALA A N   1 
ATOM   1364  C  CA  . ALA A 1 200 ? 281.731 236.220 268.584 1.00 47.80  ? 200 ALA A CA  1 
ATOM   1365  C  C   . ALA A 1 200 ? 281.880 237.329 267.553 1.00 48.10  ? 200 ALA A C   1 
ATOM   1366  O  O   . ALA A 1 200 ? 282.862 238.079 267.587 1.00 49.19  ? 200 ALA A O   1 
ATOM   1367  C  CB  . ALA A 1 200 ? 282.543 234.995 268.167 1.00 46.77  ? 200 ALA A CB  1 
ATOM   1368  N  N   . LYS A 1 201 ? 280.925 237.452 266.635 1.00 43.18  ? 201 LYS A N   1 
ATOM   1369  C  CA  . LYS A 1 201 ? 280.975 238.453 265.580 1.00 39.61  ? 201 LYS A CA  1 
ATOM   1370  C  C   . LYS A 1 201 ? 280.261 239.746 265.953 1.00 39.22  ? 201 LYS A C   1 
ATOM   1371  O  O   . LYS A 1 201 ? 280.144 240.638 265.108 1.00 41.04  ? 201 LYS A O   1 
ATOM   1372  C  CB  . LYS A 1 201 ? 280.378 237.885 264.291 1.00 41.95  ? 201 LYS A CB  1 
ATOM   1373  C  CG  . LYS A 1 201 ? 281.000 236.573 263.851 1.00 49.05  ? 201 LYS A CG  1 
ATOM   1374  C  CD  . LYS A 1 201 ? 280.928 236.403 262.343 1.00 57.76  ? 201 LYS A CD  1 
ATOM   1375  C  CE  . LYS A 1 201 ? 281.034 237.740 261.627 1.00 58.93  ? 201 LYS A CE  1 
ATOM   1376  N  NZ  . LYS A 1 201 ? 281.021 237.578 260.146 1.00 60.27  ? 201 LYS A NZ  1 
ATOM   1377  N  N   . ARG A 1 202 ? 279.785 239.871 267.190 1.00 40.14  ? 202 ARG A N   1 
ATOM   1378  C  CA  . ARG A 1 202 ? 279.080 241.069 267.627 1.00 36.28  ? 202 ARG A CA  1 
ATOM   1379  C  C   . ARG A 1 202 ? 280.005 242.132 268.203 1.00 33.62  ? 202 ARG A C   1 
ATOM   1380  O  O   . ARG A 1 202 ? 279.535 243.223 268.539 1.00 34.35  ? 202 ARG A O   1 
ATOM   1381  C  CB  . ARG A 1 202 ? 278.013 240.708 268.664 1.00 32.47  ? 202 ARG A CB  1 
ATOM   1382  C  CG  . ARG A 1 202 ? 276.873 239.883 268.109 1.00 33.76  ? 202 ARG A CG  1 
ATOM   1383  C  CD  . ARG A 1 202 ? 275.848 239.577 269.180 1.00 37.16  ? 202 ARG A CD  1 
ATOM   1384  N  NE  . ARG A 1 202 ? 275.018 238.435 268.821 1.00 35.81  ? 202 ARG A NE  1 
ATOM   1385  C  CZ  . ARG A 1 202 ? 274.514 237.573 269.692 1.00 37.91  ? 202 ARG A CZ  1 
ATOM   1386  N  NH1 . ARG A 1 202 ? 274.728 237.699 270.991 1.00 38.90  ? 202 ARG A NH1 1 
ATOM   1387  N  NH2 . ARG A 1 202 ? 273.776 236.560 269.249 1.00 39.08  ? 202 ARG A NH2 1 
ATOM   1388  N  N   . ASN A 1 203 ? 281.298 241.846 268.325 1.00 35.21  ? 203 ASN A N   1 
ATOM   1389  C  CA  . ASN A 1 203 ? 282.255 242.818 268.841 1.00 37.37  ? 203 ASN A CA  1 
ATOM   1390  C  C   . ASN A 1 203 ? 283.625 242.480 268.280 1.00 37.76  ? 203 ASN A C   1 
ATOM   1391  O  O   . ASN A 1 203 ? 284.109 241.359 268.462 1.00 43.52  ? 203 ASN A O   1 
ATOM   1392  C  CB  . ASN A 1 203 ? 282.279 242.813 270.371 1.00 39.29  ? 203 ASN A CB  1 
ATOM   1393  C  CG  . ASN A 1 203 ? 283.068 243.973 270.945 1.00 44.55  ? 203 ASN A CG  1 
ATOM   1394  O  OD1 . ASN A 1 203 ? 283.671 243.860 272.011 1.00 52.62  ? 203 ASN A OD1 1 
ATOM   1395  N  ND2 . ASN A 1 203 ? 283.071 245.095 270.236 1.00 43.62  ? 203 ASN A ND2 1 
ATOM   1396  N  N   . LEU A 1 204 ? 284.246 243.444 267.603 1.00 36.99  ? 204 LEU A N   1 
ATOM   1397  C  CA  . LEU A 1 204 ? 285.543 243.218 266.982 1.00 32.76  ? 204 LEU A CA  1 
ATOM   1398  C  C   . LEU A 1 204 ? 286.709 243.528 267.907 1.00 35.73  ? 204 LEU A C   1 
ATOM   1399  O  O   . LEU A 1 204 ? 287.832 243.092 267.630 1.00 36.96  ? 204 LEU A O   1 
ATOM   1400  C  CB  . LEU A 1 204 ? 285.668 244.050 265.703 1.00 31.96  ? 204 LEU A CB  1 
ATOM   1401  C  CG  . LEU A 1 204 ? 284.764 243.613 264.549 1.00 34.31  ? 204 LEU A CG  1 
ATOM   1402  C  CD1 . LEU A 1 204 ? 285.043 244.433 263.302 1.00 30.18  ? 204 LEU A CD1 1 
ATOM   1403  C  CD2 . LEU A 1 204 ? 284.939 242.131 264.269 1.00 30.59  ? 204 LEU A CD2 1 
ATOM   1404  N  N   . ASN A 1 205 ? 286.476 244.256 268.994 1.00 35.32  ? 205 ASN A N   1 
ATOM   1405  C  CA  . ASN A 1 205 ? 287.532 244.513 269.963 1.00 33.28  ? 205 ASN A CA  1 
ATOM   1406  C  C   . ASN A 1 205 ? 287.959 243.203 270.613 1.00 35.09  ? 205 ASN A C   1 
ATOM   1407  O  O   . ASN A 1 205 ? 287.137 242.498 271.206 1.00 42.80  ? 205 ASN A O   1 
ATOM   1408  C  CB  . ASN A 1 205 ? 287.044 245.510 271.013 1.00 31.32  ? 205 ASN A CB  1 
ATOM   1409  C  CG  . ASN A 1 205 ? 288.135 245.931 271.978 1.00 35.24  ? 205 ASN A CG  1 
ATOM   1410  O  OD1 . ASN A 1 205 ? 289.064 245.175 272.253 1.00 38.20  ? 205 ASN A OD1 1 
ATOM   1411  N  ND2 . ASN A 1 205 ? 288.024 247.146 272.499 1.00 34.45  ? 205 ASN A ND2 1 
ATOM   1412  N  N   . THR A 1 206 ? 289.247 242.875 270.501 1.00 32.09  ? 206 THR A N   1 
ATOM   1413  C  CA  . THR A 1 206 ? 289.756 241.616 271.030 1.00 35.71  ? 206 THR A CA  1 
ATOM   1414  C  C   . THR A 1 206 ? 289.985 241.650 272.535 1.00 42.58  ? 206 THR A C   1 
ATOM   1415  O  O   . THR A 1 206 ? 290.200 240.592 273.135 1.00 45.57  ? 206 THR A O   1 
ATOM   1416  C  CB  . THR A 1 206 ? 291.062 241.230 270.327 1.00 34.14  ? 206 THR A CB  1 
ATOM   1417  O  OG1 . THR A 1 206 ? 292.121 242.089 270.767 1.00 40.47  ? 206 THR A OG1 1 
ATOM   1418  C  CG2 . THR A 1 206 ? 290.916 241.344 268.817 1.00 29.86  ? 206 THR A CG2 1 
ATOM   1419  N  N   . ASP A 1 207 ? 289.948 242.830 273.157 1.00 42.31  ? 207 ASP A N   1 
ATOM   1420  C  CA  . ASP A 1 207 ? 290.068 242.917 274.607 1.00 44.01  ? 207 ASP A CA  1 
ATOM   1421  C  C   . ASP A 1 207 ? 288.809 242.443 275.317 1.00 49.61  ? 207 ASP A C   1 
ATOM   1422  O  O   . ASP A 1 207 ? 288.879 242.064 276.490 1.00 55.92  ? 207 ASP A O   1 
ATOM   1423  C  CB  . ASP A 1 207 ? 290.381 244.353 275.026 1.00 41.43  ? 207 ASP A CB  1 
ATOM   1424  C  CG  . ASP A 1 207 ? 291.794 244.768 274.679 1.00 41.73  ? 207 ASP A CG  1 
ATOM   1425  O  OD1 . ASP A 1 207 ? 292.578 243.901 274.242 1.00 40.89  ? 207 ASP A OD1 1 
ATOM   1426  O  OD2 . ASP A 1 207 ? 292.120 245.961 274.843 1.00 40.81  ? 207 ASP A OD2 1 
ATOM   1427  N  N   . ILE A 1 208 ? 287.668 242.456 274.636 1.00 49.31  ? 208 ILE A N   1 
ATOM   1428  C  CA  . ILE A 1 208 ? 286.387 242.082 275.221 1.00 53.24  ? 208 ILE A CA  1 
ATOM   1429  C  C   . ILE A 1 208 ? 286.075 240.646 274.829 1.00 56.21  ? 208 ILE A C   1 
ATOM   1430  O  O   . ILE A 1 208 ? 286.182 240.277 273.652 1.00 58.30  ? 208 ILE A O   1 
ATOM   1431  C  CB  . ILE A 1 208 ? 285.272 243.039 274.768 1.00 48.72  ? 208 ILE A CB  1 
ATOM   1432  C  CG1 . ILE A 1 208 ? 285.578 244.462 275.241 1.00 47.64  ? 208 ILE A CG1 1 
ATOM   1433  C  CG2 . ILE A 1 208 ? 283.924 242.572 275.281 1.00 46.91  ? 208 ILE A CG2 1 
ATOM   1434  C  CD1 . ILE A 1 208 ? 284.681 245.518 274.642 1.00 48.92  ? 208 ILE A CD1 1 
ATOM   1435  N  N   . LYS A 1 209 ? 285.700 239.834 275.811 1.00 61.37  ? 209 LYS A N   1 
ATOM   1436  C  CA  . LYS A 1 209 ? 285.387 238.433 275.576 1.00 71.47  ? 209 LYS A CA  1 
ATOM   1437  C  C   . LYS A 1 209 ? 283.888 238.244 275.383 1.00 74.59  ? 209 LYS A C   1 
ATOM   1438  O  O   . LYS A 1 209 ? 283.069 238.945 275.983 1.00 74.71  ? 209 LYS A O   1 
ATOM   1439  C  CB  . LYS A 1 209 ? 285.879 237.568 276.737 1.00 70.65  ? 209 LYS A CB  1 
ATOM   1440  C  CG  . LYS A 1 209 ? 287.095 236.725 276.399 1.00 72.51  ? 209 LYS A CG  1 
ATOM   1441  C  CD  . LYS A 1 209 ? 288.202 237.575 275.791 1.00 69.79  ? 209 LYS A CD  1 
ATOM   1442  C  CE  . LYS A 1 209 ? 288.959 238.351 276.856 1.00 66.02  ? 209 LYS A CE  1 
ATOM   1443  N  NZ  . LYS A 1 209 ? 289.963 239.276 276.260 1.00 61.21  ? 209 LYS A NZ  1 
ATOM   1444  N  N   . VAL A 1 210 ? 283.537 237.281 274.534 1.00 75.44  ? 210 VAL A N   1 
ATOM   1445  C  CA  . VAL A 1 210 ? 282.145 237.022 274.169 1.00 80.52  ? 210 VAL A CA  1 
ATOM   1446  C  C   . VAL A 1 210 ? 281.486 236.290 275.335 1.00 86.84  ? 210 VAL A C   1 
ATOM   1447  O  O   . VAL A 1 210 ? 281.737 235.106 275.563 1.00 88.34  ? 210 VAL A O   1 
ATOM   1448  C  CB  . VAL A 1 210 ? 282.037 236.225 272.868 1.00 76.79  ? 210 VAL A CB  1 
ATOM   1449  C  CG1 . VAL A 1 210 ? 280.621 235.711 272.679 1.00 71.61  ? 210 VAL A CG1 1 
ATOM   1450  C  CG2 . VAL A 1 210 ? 282.459 237.086 271.688 1.00 73.25  ? 210 VAL A CG2 1 
ATOM   1451  N  N   . ASP A 1 211 ? 280.642 236.995 276.075 1.00 88.53  ? 211 ASP A N   1 
ATOM   1452  C  CA  . ASP A 1 211 ? 279.921 236.377 277.180 1.00 92.01  ? 211 ASP A CA  1 
ATOM   1453  C  C   . ASP A 1 211 ? 278.832 235.463 276.626 1.00 94.24  ? 211 ASP A C   1 
ATOM   1454  O  O   . ASP A 1 211 ? 278.041 235.893 275.779 1.00 92.31  ? 211 ASP A O   1 
ATOM   1455  C  CB  . ASP A 1 211 ? 279.316 237.454 278.082 1.00 92.69  ? 211 ASP A CB  1 
ATOM   1456  C  CG  . ASP A 1 211 ? 278.647 236.882 279.321 1.00 96.34  ? 211 ASP A CG  1 
ATOM   1457  O  OD1 . ASP A 1 211 ? 278.524 237.624 280.318 1.00 97.55  ? 211 ASP A OD1 1 
ATOM   1458  O  OD2 . ASP A 1 211 ? 278.247 235.700 279.309 1.00 93.84  ? 211 ASP A OD2 1 
ATOM   1459  N  N   . PRO A 1 212 ? 278.760 234.206 277.068 1.00 96.84  ? 212 PRO A N   1 
ATOM   1460  C  CA  . PRO A 1 212 ? 277.730 233.298 276.543 1.00 99.32  ? 212 PRO A CA  1 
ATOM   1461  C  C   . PRO A 1 212 ? 276.347 233.595 277.102 1.00 96.24  ? 212 PRO A C   1 
ATOM   1462  O  O   . PRO A 1 212 ? 275.341 233.440 276.403 1.00 90.19  ? 212 PRO A O   1 
ATOM   1463  C  CB  . PRO A 1 212 ? 278.223 231.909 276.978 1.00 98.59  ? 212 PRO A CB  1 
ATOM   1464  C  CG  . PRO A 1 212 ? 279.627 232.115 277.502 1.00 94.75  ? 212 PRO A CG  1 
ATOM   1465  C  CD  . PRO A 1 212 ? 279.676 233.521 277.991 1.00 93.53  ? 212 PRO A CD  1 
ATOM   1466  N  N   . ASN A 1 213 ? 276.287 234.027 278.364 1.00 97.85  ? 213 ASN A N   1 
ATOM   1467  C  CA  . ASN A 1 213 ? 275.005 234.330 278.988 1.00 94.53  ? 213 ASN A CA  1 
ATOM   1468  C  C   . ASN A 1 213 ? 274.326 235.544 278.369 1.00 91.35  ? 213 ASN A C   1 
ATOM   1469  O  O   . ASN A 1 213 ? 273.121 235.730 278.566 1.00 88.80  ? 213 ASN A O   1 
ATOM   1470  C  CB  . ASN A 1 213 ? 275.189 234.552 280.491 1.00 94.62  ? 213 ASN A CB  1 
ATOM   1471  C  CG  . ASN A 1 213 ? 275.885 233.390 281.172 1.00 98.47  ? 213 ASN A CG  1 
ATOM   1472  O  OD1 . ASN A 1 213 ? 277.072 233.148 280.955 1.00 100.32 ? 213 ASN A OD1 1 
ATOM   1473  N  ND2 . ASN A 1 213 ? 275.147 232.665 282.005 1.00 94.08  ? 213 ASN A ND2 1 
ATOM   1474  N  N   . ALA A 1 214 ? 275.064 236.370 277.631 1.00 90.63  ? 214 ALA A N   1 
ATOM   1475  C  CA  . ALA A 1 214 ? 274.483 237.570 277.046 1.00 81.67  ? 214 ALA A CA  1 
ATOM   1476  C  C   . ALA A 1 214 ? 273.445 237.201 275.994 1.00 76.64  ? 214 ALA A C   1 
ATOM   1477  O  O   . ALA A 1 214 ? 273.706 236.381 275.108 1.00 74.18  ? 214 ALA A O   1 
ATOM   1478  C  CB  . ALA A 1 214 ? 275.574 238.442 276.430 1.00 84.87  ? 214 ALA A CB  1 
ATOM   1479  N  N   . VAL A 1 215 ? 272.267 237.810 276.093 1.00 70.20  ? 215 VAL A N   1 
ATOM   1480  C  CA  . VAL A 1 215 ? 271.183 237.596 275.145 1.00 61.30  ? 215 VAL A CA  1 
ATOM   1481  C  C   . VAL A 1 215 ? 270.755 238.948 274.595 1.00 53.89  ? 215 VAL A C   1 
ATOM   1482  O  O   . VAL A 1 215 ? 270.675 239.934 275.336 1.00 55.33  ? 215 VAL A O   1 
ATOM   1483  C  CB  . VAL A 1 215 ? 269.986 236.868 275.793 1.00 61.60  ? 215 VAL A CB  1 
ATOM   1484  C  CG1 . VAL A 1 215 ? 270.475 235.788 276.745 1.00 66.90  ? 215 VAL A CG1 1 
ATOM   1485  C  CG2 . VAL A 1 215 ? 269.078 237.855 276.507 1.00 54.45  ? 215 VAL A CG2 1 
ATOM   1486  N  N   . VAL A 1 216 ? 270.498 238.998 273.293 1.00 51.07  ? 216 VAL A N   1 
ATOM   1487  C  CA  . VAL A 1 216 ? 270.026 240.207 272.631 1.00 44.89  ? 216 VAL A CA  1 
ATOM   1488  C  C   . VAL A 1 216 ? 268.530 240.062 272.398 1.00 42.89  ? 216 VAL A C   1 
ATOM   1489  O  O   . VAL A 1 216 ? 268.082 239.100 271.764 1.00 45.33  ? 216 VAL A O   1 
ATOM   1490  C  CB  . VAL A 1 216 ? 270.773 240.453 271.311 1.00 42.41  ? 216 VAL A CB  1 
ATOM   1491  C  CG1 . VAL A 1 216 ? 270.540 241.874 270.826 1.00 37.28  ? 216 VAL A CG1 1 
ATOM   1492  C  CG2 . VAL A 1 216 ? 272.255 240.186 271.490 1.00 41.56  ? 216 VAL A CG2 1 
ATOM   1493  N  N   . MET A 1 217 ? 267.756 241.013 272.910 1.00 41.66  ? 217 MET A N   1 
ATOM   1494  C  CA  . MET A 1 217 ? 266.314 241.018 272.719 1.00 40.00  ? 217 MET A CA  1 
ATOM   1495  C  C   . MET A 1 217 ? 265.975 241.780 271.447 1.00 40.34  ? 217 MET A C   1 
ATOM   1496  O  O   . MET A 1 217 ? 266.490 242.879 271.218 1.00 46.49  ? 217 MET A O   1 
ATOM   1497  C  CB  . MET A 1 217 ? 265.609 241.647 273.921 1.00 39.08  ? 217 MET A CB  1 
ATOM   1498  C  CG  . MET A 1 217 ? 265.546 240.749 275.141 1.00 40.06  ? 217 MET A CG  1 
ATOM   1499  S  SD  . MET A 1 217 ? 264.565 239.266 274.854 1.00 53.06  ? 217 MET A SD  1 
ATOM   1500  C  CE  . MET A 1 217 ? 265.438 238.084 275.874 1.00 42.37  ? 217 MET A CE  1 
ATOM   1501  N  N   . ILE A 1 218 ? 265.110 241.195 270.624 1.00 38.34  ? 218 ILE A N   1 
ATOM   1502  C  CA  . ILE A 1 218 ? 264.694 241.791 269.365 1.00 38.98  ? 218 ILE A CA  1 
ATOM   1503  C  C   . ILE A 1 218 ? 263.175 241.798 269.308 1.00 37.73  ? 218 ILE A C   1 
ATOM   1504  O  O   . ILE A 1 218 ? 262.507 240.916 269.859 1.00 42.67  ? 218 ILE A O   1 
ATOM   1505  C  CB  . ILE A 1 218 ? 265.282 241.039 268.150 1.00 39.13  ? 218 ILE A CB  1 
ATOM   1506  C  CG1 . ILE A 1 218 ? 264.985 239.543 268.252 1.00 36.49  ? 218 ILE A CG1 1 
ATOM   1507  C  CG2 . ILE A 1 218 ? 266.778 241.277 268.047 1.00 33.38  ? 218 ILE A CG2 1 
ATOM   1508  C  CD1 . ILE A 1 218 ? 263.666 239.138 267.637 1.00 35.74  ? 218 ILE A CD1 1 
ATOM   1509  N  N   . SER A 1 219 ? 262.633 242.801 268.623 1.00 36.75  ? 219 SER A N   1 
ATOM   1510  C  CA  . SER A 1 219 ? 261.198 242.967 268.450 1.00 35.47  ? 219 SER A CA  1 
ATOM   1511  C  C   . SER A 1 219 ? 260.829 242.833 266.980 1.00 33.63  ? 219 SER A C   1 
ATOM   1512  O  O   . SER A 1 219 ? 261.558 243.300 266.100 1.00 34.61  ? 219 SER A O   1 
ATOM   1513  C  CB  . SER A 1 219 ? 260.733 244.326 268.977 1.00 32.72  ? 219 SER A CB  1 
ATOM   1514  O  OG  . SER A 1 219 ? 260.522 244.288 270.377 1.00 37.78  ? 219 SER A OG  1 
ATOM   1515  N  N   . LYS A 1 220 ? 259.695 242.188 266.723 1.00 32.80  ? 220 LYS A N   1 
ATOM   1516  C  CA  . LYS A 1 220 ? 259.173 242.047 265.372 1.00 33.19  ? 220 LYS A CA  1 
ATOM   1517  C  C   . LYS A 1 220 ? 257.655 242.121 265.411 1.00 33.39  ? 220 LYS A C   1 
ATOM   1518  O  O   . LYS A 1 220 ? 257.031 241.919 266.451 1.00 34.66  ? 220 LYS A O   1 
ATOM   1519  C  CB  . LYS A 1 220 ? 259.618 240.734 264.716 1.00 31.24  ? 220 LYS A CB  1 
ATOM   1520  C  CG  . LYS A 1 220 ? 259.040 239.490 265.359 1.00 35.58  ? 220 LYS A CG  1 
ATOM   1521  C  CD  . LYS A 1 220 ? 259.412 238.255 264.567 1.00 33.14  ? 220 LYS A CD  1 
ATOM   1522  C  CE  . LYS A 1 220 ? 258.247 237.781 263.723 1.00 39.35  ? 220 LYS A CE  1 
ATOM   1523  N  NZ  . LYS A 1 220 ? 258.707 237.019 262.534 1.00 46.22  ? 220 LYS A NZ  1 
ATOM   1524  N  N   . ASP A 1 221 ? 257.064 242.427 264.264 1.00 34.87  ? 221 ASP A N   1 
ATOM   1525  C  CA  . ASP A 1 221 ? 255.618 242.512 264.129 1.00 30.77  ? 221 ASP A CA  1 
ATOM   1526  C  C   . ASP A 1 221 ? 255.087 241.259 263.447 1.00 32.14  ? 221 ASP A C   1 
ATOM   1527  O  O   . ASP A 1 221 ? 255.647 240.804 262.446 1.00 33.34  ? 221 ASP A O   1 
ATOM   1528  C  CB  . ASP A 1 221 ? 255.218 243.747 263.319 1.00 27.57  ? 221 ASP A CB  1 
ATOM   1529  C  CG  . ASP A 1 221 ? 255.378 245.031 264.099 1.00 34.79  ? 221 ASP A CG  1 
ATOM   1530  O  OD1 . ASP A 1 221 ? 254.888 245.096 265.244 1.00 43.72  ? 221 ASP A OD1 1 
ATOM   1531  O  OD2 . ASP A 1 221 ? 255.993 245.977 263.565 1.00 37.30  ? 221 ASP A OD2 1 
ATOM   1532  N  N   . THR A 1 222 ? 254.012 240.695 263.995 1.00 31.27  ? 222 THR A N   1 
ATOM   1533  C  CA  . THR A 1 222 ? 253.316 239.610 263.318 1.00 32.43  ? 222 THR A CA  1 
ATOM   1534  C  C   . THR A 1 222 ? 251.816 239.840 263.413 1.00 38.39  ? 222 THR A C   1 
ATOM   1535  O  O   . THR A 1 222 ? 251.325 240.555 264.289 1.00 39.11  ? 222 THR A O   1 
ATOM   1536  C  CB  . THR A 1 222 ? 253.679 238.223 263.879 1.00 42.33  ? 222 THR A CB  1 
ATOM   1537  O  OG1 . THR A 1 222 ? 253.034 237.210 263.090 1.00 46.91  ? 222 THR A OG1 1 
ATOM   1538  C  CG2 . THR A 1 222 ? 253.235 238.096 265.329 1.00 37.90  ? 222 THR A CG2 1 
ATOM   1539  N  N   . ALA A 1 223 ? 251.095 239.245 262.467 1.00 39.15  ? 223 ALA A N   1 
ATOM   1540  C  CA  . ALA A 1 223 ? 249.646 239.335 262.425 1.00 35.67  ? 223 ALA A CA  1 
ATOM   1541  C  C   . ALA A 1 223 ? 249.099 238.051 261.824 1.00 42.13  ? 223 ALA A C   1 
ATOM   1542  O  O   . ALA A 1 223 ? 249.764 237.394 261.020 1.00 44.81  ? 223 ALA A O   1 
ATOM   1543  C  CB  . ALA A 1 223 ? 249.176 240.549 261.616 1.00 30.07  ? 223 ALA A CB  1 
ATOM   1544  N  N   . PHE A 1 224 ? 247.883 237.697 262.227 1.00 47.50  ? 224 PHE A N   1 
ATOM   1545  C  CA  . PHE A 1 224 ? 247.246 236.507 261.681 1.00 49.11  ? 224 PHE A CA  1 
ATOM   1546  C  C   . PHE A 1 224 ? 245.745 236.587 261.899 1.00 50.63  ? 224 PHE A C   1 
ATOM   1547  O  O   . PHE A 1 224 ? 245.262 237.267 262.805 1.00 52.25  ? 224 PHE A O   1 
ATOM   1548  C  CB  . PHE A 1 224 ? 247.810 235.226 262.307 1.00 51.01  ? 224 PHE A CB  1 
ATOM   1549  C  CG  . PHE A 1 224 ? 247.812 235.232 263.809 1.00 53.28  ? 224 PHE A CG  1 
ATOM   1550  C  CD1 . PHE A 1 224 ? 248.886 235.752 264.512 1.00 52.45  ? 224 PHE A CD1 1 
ATOM   1551  C  CD2 . PHE A 1 224 ? 246.740 234.719 264.518 1.00 54.48  ? 224 PHE A CD2 1 
ATOM   1552  C  CE1 . PHE A 1 224 ? 248.890 235.760 265.890 1.00 50.02  ? 224 PHE A CE1 1 
ATOM   1553  C  CE2 . PHE A 1 224 ? 246.739 234.725 265.898 1.00 52.36  ? 224 PHE A CE2 1 
ATOM   1554  C  CZ  . PHE A 1 224 ? 247.815 235.246 266.584 1.00 51.69  ? 224 PHE A CZ  1 
ATOM   1555  N  N   . VAL A 1 225 ? 245.012 235.863 261.060 1.00 55.41  ? 225 VAL A N   1 
ATOM   1556  C  CA  . VAL A 1 225 ? 243.566 235.741 261.183 1.00 60.88  ? 225 VAL A CA  1 
ATOM   1557  C  C   . VAL A 1 225 ? 243.264 234.440 261.912 1.00 64.00  ? 225 VAL A C   1 
ATOM   1558  O  O   . VAL A 1 225 ? 243.732 233.368 261.508 1.00 62.83  ? 225 VAL A O   1 
ATOM   1559  C  CB  . VAL A 1 225 ? 242.880 235.788 259.806 1.00 61.41  ? 225 VAL A CB  1 
ATOM   1560  C  CG1 . VAL A 1 225 ? 243.510 236.868 258.940 1.00 55.09  ? 225 VAL A CG1 1 
ATOM   1561  C  CG2 . VAL A 1 225 ? 242.958 234.440 259.112 1.00 63.85  ? 225 VAL A CG2 1 
ATOM   1562  N  N   . ASP A 1 226 ? 242.512 234.535 263.003 1.00 69.62  ? 226 ASP A N   1 
ATOM   1563  C  CA  . ASP A 1 226 ? 242.160 233.364 263.787 1.00 76.61  ? 226 ASP A CA  1 
ATOM   1564  C  C   . ASP A 1 226 ? 240.889 232.723 263.232 1.00 81.30  ? 226 ASP A C   1 
ATOM   1565  O  O   . ASP A 1 226 ? 240.252 233.235 262.309 1.00 81.23  ? 226 ASP A O   1 
ATOM   1566  C  CB  . ASP A 1 226 ? 242.011 233.734 265.262 1.00 76.51  ? 226 ASP A CB  1 
ATOM   1567  C  CG  . ASP A 1 226 ? 240.899 234.735 265.508 1.00 82.39  ? 226 ASP A CG  1 
ATOM   1568  O  OD1 . ASP A 1 226 ? 240.201 235.111 264.543 1.00 79.82  ? 226 ASP A OD1 1 
ATOM   1569  O  OD2 . ASP A 1 226 ? 240.722 235.148 266.672 1.00 82.92  ? 226 ASP A OD2 1 
ATOM   1570  N  N   . GLU A 1 227 ? 240.514 231.578 263.808 1.00 84.40  ? 227 GLU A N   1 
ATOM   1571  C  CA  . GLU A 1 227 ? 239.345 230.850 263.325 1.00 87.64  ? 227 GLU A CA  1 
ATOM   1572  C  C   . GLU A 1 227 ? 238.088 231.710 263.355 1.00 86.66  ? 227 GLU A C   1 
ATOM   1573  O  O   . GLU A 1 227 ? 237.207 231.550 262.503 1.00 86.95  ? 227 GLU A O   1 
ATOM   1574  C  CB  . GLU A 1 227 ? 239.139 229.580 264.152 1.00 87.99  ? 227 GLU A CB  1 
ATOM   1575  C  CG  . GLU A 1 227 ? 238.644 229.822 265.573 1.00 93.22  ? 227 GLU A CG  1 
ATOM   1576  C  CD  . GLU A 1 227 ? 239.642 230.585 266.423 1.00 92.47  ? 227 GLU A CD  1 
ATOM   1577  O  OE1 . GLU A 1 227 ? 240.811 230.154 266.504 1.00 90.09  ? 227 GLU A OE1 1 
ATOM   1578  O  OE2 . GLU A 1 227 ? 239.258 231.618 267.010 1.00 88.99  ? 227 GLU A OE2 1 
ATOM   1579  N  N   . SER A 1 228 ? 237.985 232.627 264.318 1.00 86.41  ? 228 SER A N   1 
ATOM   1580  C  CA  . SER A 1 228 ? 236.819 233.497 264.409 1.00 85.29  ? 228 SER A CA  1 
ATOM   1581  C  C   . SER A 1 228 ? 236.782 234.550 263.310 1.00 85.18  ? 228 SER A C   1 
ATOM   1582  O  O   . SER A 1 228 ? 235.784 235.270 263.202 1.00 82.34  ? 228 SER A O   1 
ATOM   1583  C  CB  . SER A 1 228 ? 236.778 234.180 265.776 1.00 84.81  ? 228 SER A CB  1 
ATOM   1584  O  OG  . SER A 1 228 ? 237.248 233.314 266.795 1.00 85.68  ? 228 SER A OG  1 
ATOM   1585  N  N   . GLY A 1 229 ? 237.837 234.662 262.503 1.00 81.40  ? 229 GLY A N   1 
ATOM   1586  C  CA  . GLY A 1 229 ? 237.909 235.662 261.461 1.00 72.92  ? 229 GLY A CA  1 
ATOM   1587  C  C   . GLY A 1 229 ? 238.444 237.008 261.896 1.00 75.99  ? 229 GLY A C   1 
ATOM   1588  O  O   . GLY A 1 229 ? 238.437 237.947 261.090 1.00 72.50  ? 229 GLY A O   1 
ATOM   1589  N  N   . ASN A 1 230 ? 238.902 237.136 263.138 1.00 79.63  ? 230 ASN A N   1 
ATOM   1590  C  CA  . ASN A 1 230 ? 239.420 238.396 263.652 1.00 71.83  ? 230 ASN A CA  1 
ATOM   1591  C  C   . ASN A 1 230 ? 240.921 238.489 263.411 1.00 66.67  ? 230 ASN A C   1 
ATOM   1592  O  O   . ASN A 1 230 ? 241.642 237.492 263.511 1.00 64.56  ? 230 ASN A O   1 
ATOM   1593  C  CB  . ASN A 1 230 ? 239.129 238.533 265.148 1.00 73.38  ? 230 ASN A CB  1 
ATOM   1594  C  CG  . ASN A 1 230 ? 237.658 238.370 265.478 1.00 79.01  ? 230 ASN A CG  1 
ATOM   1595  O  OD1 . ASN A 1 230 ? 236.889 237.808 264.699 1.00 77.90  ? 230 ASN A OD1 1 
ATOM   1596  N  ND2 . ASN A 1 230 ? 237.259 238.864 266.644 1.00 80.57  ? 230 ASN A ND2 1 
ATOM   1597  N  N   . ILE A 1 231 ? 241.384 239.693 263.097 1.00 59.26  ? 231 ILE A N   1 
ATOM   1598  C  CA  . ILE A 1 231 ? 242.798 239.943 262.844 1.00 51.15  ? 231 ILE A CA  1 
ATOM   1599  C  C   . ILE A 1 231 ? 243.479 240.245 264.171 1.00 50.88  ? 231 ILE A C   1 
ATOM   1600  O  O   . ILE A 1 231 ? 243.125 241.212 264.855 1.00 48.43  ? 231 ILE A O   1 
ATOM   1601  C  CB  . ILE A 1 231 ? 242.991 241.101 261.853 1.00 51.85  ? 231 ILE A CB  1 
ATOM   1602  C  CG1 . ILE A 1 231 ? 242.118 240.901 260.614 1.00 53.94  ? 231 ILE A CG1 1 
ATOM   1603  C  CG2 . ILE A 1 231 ? 244.456 241.226 261.461 1.00 48.10  ? 231 ILE A CG2 1 
ATOM   1604  C  CD1 . ILE A 1 231 ? 242.597 239.800 259.702 1.00 55.44  ? 231 ILE A CD1 1 
ATOM   1605  N  N   . ILE A 1 232 ? 244.458 239.422 264.537 1.00 51.13  ? 232 ILE A N   1 
ATOM   1606  C  CA  . ILE A 1 232 ? 245.246 239.607 265.748 1.00 49.28  ? 232 ILE A CA  1 
ATOM   1607  C  C   . ILE A 1 232 ? 246.641 240.043 265.327 1.00 40.81  ? 232 ILE A C   1 
ATOM   1608  O  O   . ILE A 1 232 ? 247.321 239.332 264.577 1.00 45.49  ? 232 ILE A O   1 
ATOM   1609  C  CB  . ILE A 1 232 ? 245.297 238.326 266.593 1.00 48.74  ? 232 ILE A CB  1 
ATOM   1610  C  CG1 . ILE A 1 232 ? 243.885 237.800 266.852 1.00 51.75  ? 232 ILE A CG1 1 
ATOM   1611  C  CG2 . ILE A 1 232 ? 246.017 238.584 267.904 1.00 45.19  ? 232 ILE A CG2 1 
ATOM   1612  C  CD1 . ILE A 1 232 ? 242.977 238.803 267.530 1.00 53.83  ? 232 ILE A CD1 1 
ATOM   1613  N  N   . SER A 1 233 ? 247.059 241.213 265.800 1.00 36.66  ? 233 SER A N   1 
ATOM   1614  C  CA  . SER A 1 233 ? 248.382 241.756 265.537 1.00 39.50  ? 233 SER A CA  1 
ATOM   1615  C  C   . SER A 1 233 ? 249.129 241.906 266.852 1.00 42.34  ? 233 SER A C   1 
ATOM   1616  O  O   . SER A 1 233 ? 248.534 242.258 267.875 1.00 46.04  ? 233 SER A O   1 
ATOM   1617  C  CB  . SER A 1 233 ? 248.295 243.110 264.827 1.00 40.37  ? 233 SER A CB  1 
ATOM   1618  O  OG  . SER A 1 233 ? 248.041 242.947 263.443 1.00 46.43  ? 233 SER A OG  1 
ATOM   1619  N  N   . GLU A 1 234 ? 250.433 241.638 266.829 1.00 43.44  ? 234 GLU A N   1 
ATOM   1620  C  CA  . GLU A 1 234 ? 251.228 241.755 268.041 1.00 39.75  ? 234 GLU A CA  1 
ATOM   1621  C  C   . GLU A 1 234 ? 252.680 242.050 267.699 1.00 39.42  ? 234 GLU A C   1 
ATOM   1622  O  O   . GLU A 1 234 ? 253.137 241.855 266.567 1.00 41.24  ? 234 GLU A O   1 
ATOM   1623  C  CB  . GLU A 1 234 ? 251.142 240.490 268.901 1.00 41.06  ? 234 GLU A CB  1 
ATOM   1624  C  CG  . GLU A 1 234 ? 251.160 239.195 268.118 1.00 52.09  ? 234 GLU A CG  1 
ATOM   1625  C  CD  . GLU A 1 234 ? 251.458 237.999 268.996 1.00 62.88  ? 234 GLU A CD  1 
ATOM   1626  O  OE1 . GLU A 1 234 ? 252.106 238.186 270.047 1.00 62.39  ? 234 GLU A OE1 1 
ATOM   1627  O  OE2 . GLU A 1 234 ? 251.050 236.874 268.638 1.00 65.26  ? 234 GLU A OE2 1 
ATOM   1628  N  N   . THR A 1 235 ? 253.391 242.547 268.707 1.00 40.12  ? 235 THR A N   1 
ATOM   1629  C  CA  . THR A 1 235 ? 254.830 242.757 268.658 1.00 36.66  ? 235 THR A CA  1 
ATOM   1630  C  C   . THR A 1 235 ? 255.490 241.728 269.566 1.00 38.83  ? 235 THR A C   1 
ATOM   1631  O  O   . THR A 1 235 ? 255.291 241.750 270.785 1.00 41.23  ? 235 THR A O   1 
ATOM   1632  C  CB  . THR A 1 235 ? 255.197 244.177 269.089 1.00 36.22  ? 235 THR A CB  1 
ATOM   1633  O  OG1 . THR A 1 235 ? 254.317 245.112 268.456 1.00 39.97  ? 235 THR A OG1 1 
ATOM   1634  C  CG2 . THR A 1 235 ? 256.633 244.501 268.704 1.00 33.19  ? 235 THR A CG2 1 
ATOM   1635  N  N   . ILE A 1 236 ? 256.260 240.832 268.968 1.00 40.00  ? 236 ILE A N   1 
ATOM   1636  C  CA  . ILE A 1 236 ? 256.969 239.786 269.692 1.00 38.58  ? 236 ILE A CA  1 
ATOM   1637  C  C   . ILE A 1 236 ? 258.350 240.300 270.068 1.00 41.49  ? 236 ILE A C   1 
ATOM   1638  O  O   . ILE A 1 236 ? 259.095 240.789 269.210 1.00 42.23  ? 236 ILE A O   1 
ATOM   1639  C  CB  . ILE A 1 236 ? 257.074 238.508 268.844 1.00 40.14  ? 236 ILE A CB  1 
ATOM   1640  C  CG1 . ILE A 1 236 ? 255.710 237.828 268.722 1.00 41.02  ? 236 ILE A CG1 1 
ATOM   1641  C  CG2 . ILE A 1 236 ? 258.104 237.563 269.434 1.00 41.39  ? 236 ILE A CG2 1 
ATOM   1642  C  CD1 . ILE A 1 236 ? 255.676 236.725 267.693 1.00 47.66  ? 236 ILE A CD1 1 
ATOM   1643  N  N   . THR A 1 237 ? 258.689 240.192 271.349 1.00 39.02  ? 237 THR A N   1 
ATOM   1644  C  CA  . THR A 1 237 ? 260.019 240.512 271.856 1.00 39.24  ? 237 THR A CA  1 
ATOM   1645  C  C   . THR A 1 237 ? 260.634 239.217 272.368 1.00 39.34  ? 237 THR A C   1 
ATOM   1646  O  O   . THR A 1 237 ? 260.121 238.613 273.315 1.00 45.20  ? 237 THR A O   1 
ATOM   1647  C  CB  . THR A 1 237 ? 259.955 241.565 272.960 1.00 41.32  ? 237 THR A CB  1 
ATOM   1648  O  OG1 . THR A 1 237 ? 259.341 242.755 272.451 1.00 44.20  ? 237 THR A OG1 1 
ATOM   1649  C  CG2 . THR A 1 237 ? 261.353 241.899 273.457 1.00 38.54  ? 237 THR A CG2 1 
ATOM   1650  N  N   . ARG A 1 238 ? 261.725 238.789 271.744 1.00 39.69  ? 238 ARG A N   1 
ATOM   1651  C  CA  . ARG A 1 238 ? 262.322 237.507 272.083 1.00 37.53  ? 238 ARG A CA  1 
ATOM   1652  C  C   . ARG A 1 238 ? 263.821 237.580 271.855 1.00 37.79  ? 238 ARG A C   1 
ATOM   1653  O  O   . ARG A 1 238 ? 264.306 238.480 271.161 1.00 36.90  ? 238 ARG A O   1 
ATOM   1654  C  CB  . ARG A 1 238 ? 261.718 236.365 271.257 1.00 35.92  ? 238 ARG A CB  1 
ATOM   1655  C  CG  . ARG A 1 238 ? 262.017 236.452 269.775 1.00 37.15  ? 238 ARG A CG  1 
ATOM   1656  C  CD  . ARG A 1 238 ? 261.018 235.649 268.973 1.00 38.14  ? 238 ARG A CD  1 
ATOM   1657  N  NE  . ARG A 1 238 ? 261.474 235.419 267.609 1.00 39.46  ? 238 ARG A NE  1 
ATOM   1658  C  CZ  . ARG A 1 238 ? 260.702 234.976 266.628 1.00 44.62  ? 238 ARG A CZ  1 
ATOM   1659  N  NH1 . ARG A 1 238 ? 259.425 234.698 266.827 1.00 51.20  ? 238 ARG A NH1 1 
ATOM   1660  N  NH2 . ARG A 1 238 ? 261.224 234.806 265.417 1.00 41.13  ? 238 ARG A NH2 1 
ATOM   1661  N  N   . PRO A 1 239 ? 264.584 236.656 272.436 1.00 39.40  ? 239 PRO A N   1 
ATOM   1662  C  CA  . PRO A 1 239 ? 266.025 236.618 272.168 1.00 38.14  ? 239 PRO A CA  1 
ATOM   1663  C  C   . PRO A 1 239 ? 266.310 236.372 270.695 1.00 39.70  ? 239 PRO A C   1 
ATOM   1664  O  O   . PRO A 1 239 ? 265.584 235.650 270.008 1.00 36.84  ? 239 PRO A O   1 
ATOM   1665  C  CB  . PRO A 1 239 ? 266.519 235.453 273.034 1.00 35.05  ? 239 PRO A CB  1 
ATOM   1666  C  CG  . PRO A 1 239 ? 265.472 235.277 274.075 1.00 34.06  ? 239 PRO A CG  1 
ATOM   1667  C  CD  . PRO A 1 239 ? 264.176 235.659 273.437 1.00 34.24  ? 239 PRO A CD  1 
ATOM   1668  N  N   . LEU A 1 240 ? 267.389 236.982 270.216 1.00 41.16  ? 240 LEU A N   1 
ATOM   1669  C  CA  . LEU A 1 240 ? 267.769 236.864 268.815 1.00 36.86  ? 240 LEU A CA  1 
ATOM   1670  C  C   . LEU A 1 240 ? 268.387 235.496 268.555 1.00 40.26  ? 240 LEU A C   1 
ATOM   1671  O  O   . LEU A 1 240 ? 269.431 235.161 269.123 1.00 44.86  ? 240 LEU A O   1 
ATOM   1672  C  CB  . LEU A 1 240 ? 268.747 237.976 268.448 1.00 37.08  ? 240 LEU A CB  1 
ATOM   1673  C  CG  . LEU A 1 240 ? 269.687 237.701 267.275 1.00 41.36  ? 240 LEU A CG  1 
ATOM   1674  C  CD1 . LEU A 1 240 ? 268.952 237.873 265.958 1.00 37.99  ? 240 LEU A CD1 1 
ATOM   1675  C  CD2 . LEU A 1 240 ? 270.903 238.610 267.337 1.00 35.77  ? 240 LEU A CD2 1 
ATOM   1676  N  N   . SER A 1 241 ? 267.744 234.703 267.698 1.00 41.68  ? 241 SER A N   1 
ATOM   1677  C  CA  . SER A 1 241 ? 268.247 233.378 267.361 1.00 39.74  ? 241 SER A CA  1 
ATOM   1678  C  C   . SER A 1 241 ? 268.244 233.055 265.875 1.00 40.45  ? 241 SER A C   1 
ATOM   1679  O  O   . SER A 1 241 ? 269.023 232.189 265.460 1.00 44.58  ? 241 SER A O   1 
ATOM   1680  C  CB  . SER A 1 241 ? 267.442 232.295 268.095 1.00 38.43  ? 241 SER A CB  1 
ATOM   1681  O  OG  . SER A 1 241 ? 266.060 232.604 268.110 1.00 45.47  ? 241 SER A OG  1 
ATOM   1682  N  N   . SER A 1 242 ? 267.419 233.709 265.060 1.00 40.75  ? 242 SER A N   1 
ATOM   1683  C  CA  . SER A 1 242 ? 267.298 233.331 263.660 1.00 39.70  ? 242 SER A CA  1 
ATOM   1684  C  C   . SER A 1 242 ? 266.914 234.543 262.824 1.00 36.78  ? 242 SER A C   1 
ATOM   1685  O  O   . SER A 1 242 ? 266.616 235.620 263.344 1.00 38.03  ? 242 SER A O   1 
ATOM   1686  C  CB  . SER A 1 242 ? 266.277 232.204 263.475 1.00 39.38  ? 242 SER A CB  1 
ATOM   1687  O  OG  . SER A 1 242 ? 264.958 232.663 263.715 1.00 41.30  ? 242 SER A OG  1 
ATOM   1688  N  N   . GLU A 1 243 ? 266.925 234.343 261.504 1.00 36.19  ? 243 GLU A N   1 
ATOM   1689  C  CA  . GLU A 1 243 ? 266.607 235.408 260.562 1.00 38.77  ? 243 GLU A CA  1 
ATOM   1690  C  C   . GLU A 1 243 ? 265.138 235.801 260.607 1.00 38.38  ? 243 GLU A C   1 
ATOM   1691  O  O   . GLU A 1 243 ? 264.803 236.939 260.260 1.00 37.93  ? 243 GLU A O   1 
ATOM   1692  C  CB  . GLU A 1 243 ? 266.986 234.980 259.143 1.00 36.13  ? 243 GLU A CB  1 
ATOM   1693  C  CG  . GLU A 1 243 ? 268.458 234.639 258.958 1.00 42.25  ? 243 GLU A CG  1 
ATOM   1694  C  CD  . GLU A 1 243 ? 268.752 233.163 259.176 1.00 52.49  ? 243 GLU A CD  1 
ATOM   1695  O  OE1 . GLU A 1 243 ? 268.345 232.613 260.218 1.00 53.45  ? 243 GLU A OE1 1 
ATOM   1696  O  OE2 . GLU A 1 243 ? 269.389 232.547 258.298 1.00 51.63  ? 243 GLU A OE2 1 
ATOM   1697  N  N   . TYR A 1 244 ? 264.259 234.896 261.042 1.00 36.96  ? 244 TYR A N   1 
ATOM   1698  C  CA  . TYR A 1 244 ? 262.846 235.233 261.157 1.00 35.60  ? 244 TYR A CA  1 
ATOM   1699  C  C   . TYR A 1 244 ? 262.613 236.343 262.169 1.00 36.93  ? 244 TYR A C   1 
ATOM   1700  O  O   . TYR A 1 244 ? 261.533 236.940 262.182 1.00 41.30  ? 244 TYR A O   1 
ATOM   1701  C  CB  . TYR A 1 244 ? 262.036 233.997 261.542 1.00 41.73  ? 244 TYR A CB  1 
ATOM   1702  C  CG  . TYR A 1 244 ? 261.880 232.994 260.426 1.00 49.08  ? 244 TYR A CG  1 
ATOM   1703  C  CD1 . TYR A 1 244 ? 260.989 233.216 259.385 1.00 46.64  ? 244 TYR A CD1 1 
ATOM   1704  C  CD2 . TYR A 1 244 ? 262.618 231.819 260.415 1.00 50.93  ? 244 TYR A CD2 1 
ATOM   1705  C  CE1 . TYR A 1 244 ? 260.843 232.302 258.364 1.00 47.49  ? 244 TYR A CE1 1 
ATOM   1706  C  CE2 . TYR A 1 244 ? 262.478 230.899 259.398 1.00 54.28  ? 244 TYR A CE2 1 
ATOM   1707  C  CZ  . TYR A 1 244 ? 261.589 231.144 258.375 1.00 51.33  ? 244 TYR A CZ  1 
ATOM   1708  O  OH  . TYR A 1 244 ? 261.448 230.226 257.361 1.00 49.26  ? 244 TYR A OH  1 
ATOM   1709  N  N   . ASP A 1 245 ? 263.601 236.625 263.017 1.00 35.18  ? 245 ASP A N   1 
ATOM   1710  C  CA  . ASP A 1 245 ? 263.522 237.746 263.941 1.00 33.95  ? 245 ASP A CA  1 
ATOM   1711  C  C   . ASP A 1 245 ? 263.511 239.090 263.228 1.00 32.09  ? 245 ASP A C   1 
ATOM   1712  O  O   . ASP A 1 245 ? 263.195 240.103 263.860 1.00 36.02  ? 245 ASP A O   1 
ATOM   1713  C  CB  . ASP A 1 245 ? 264.694 237.696 264.921 1.00 35.08  ? 245 ASP A CB  1 
ATOM   1714  C  CG  . ASP A 1 245 ? 264.609 236.522 265.877 1.00 42.49  ? 245 ASP A CG  1 
ATOM   1715  O  OD1 . ASP A 1 245 ? 263.921 235.532 265.556 1.00 43.66  ? 245 ASP A OD1 1 
ATOM   1716  O  OD2 . ASP A 1 245 ? 265.237 236.588 266.952 1.00 44.80  ? 245 ASP A OD2 1 
ATOM   1717  N  N   . PHE A 1 246 ? 263.846 239.128 261.939 1.00 30.98  ? 246 PHE A N   1 
ATOM   1718  C  CA  . PHE A 1 246 ? 263.890 240.370 261.181 1.00 29.48  ? 246 PHE A CA  1 
ATOM   1719  C  C   . PHE A 1 246 ? 262.777 240.469 260.147 1.00 31.24  ? 246 PHE A C   1 
ATOM   1720  O  O   . PHE A 1 246 ? 262.832 241.340 259.273 1.00 34.43  ? 246 PHE A O   1 
ATOM   1721  C  CB  . PHE A 1 246 ? 265.256 240.527 260.509 1.00 27.44  ? 246 PHE A CB  1 
ATOM   1722  C  CG  . PHE A 1 246 ? 266.411 240.398 261.457 1.00 31.31  ? 246 PHE A CG  1 
ATOM   1723  C  CD1 . PHE A 1 246 ? 266.608 241.334 262.456 1.00 29.02  ? 246 PHE A CD1 1 
ATOM   1724  C  CD2 . PHE A 1 246 ? 267.297 239.339 261.354 1.00 30.65  ? 246 PHE A CD2 1 
ATOM   1725  C  CE1 . PHE A 1 246 ? 267.664 241.218 263.333 1.00 25.72  ? 246 PHE A CE1 1 
ATOM   1726  C  CE2 . PHE A 1 246 ? 268.357 239.220 262.229 1.00 29.97  ? 246 PHE A CE2 1 
ATOM   1727  C  CZ  . PHE A 1 246 ? 268.541 240.161 263.219 1.00 32.13  ? 246 PHE A CZ  1 
ATOM   1728  N  N   . LEU A 1 247 ? 261.769 239.607 260.226 1.00 32.50  ? 247 LEU A N   1 
ATOM   1729  C  CA  . LEU A 1 247 ? 260.629 239.636 259.319 1.00 31.55  ? 247 LEU A CA  1 
ATOM   1730  C  C   . LEU A 1 247 ? 259.417 240.198 260.049 1.00 29.34  ? 247 LEU A C   1 
ATOM   1731  O  O   . LEU A 1 247 ? 259.070 239.726 261.136 1.00 37.06  ? 247 LEU A O   1 
ATOM   1732  C  CB  . LEU A 1 247 ? 260.325 238.237 258.779 1.00 32.99  ? 247 LEU A CB  1 
ATOM   1733  C  CG  . LEU A 1 247 ? 259.112 238.122 257.854 1.00 34.58  ? 247 LEU A CG  1 
ATOM   1734  C  CD1 . LEU A 1 247 ? 259.405 238.750 256.501 1.00 28.30  ? 247 LEU A CD1 1 
ATOM   1735  C  CD2 . LEU A 1 247 ? 258.699 236.670 257.697 1.00 39.41  ? 247 LEU A CD2 1 
ATOM   1736  N  N   . ASN A 1 248 ? 258.778 241.201 259.452 1.00 29.08  ? 248 ASN A N   1 
ATOM   1737  C  CA  . ASN A 1 248 ? 257.612 241.857 260.031 1.00 27.35  ? 248 ASN A CA  1 
ATOM   1738  C  C   . ASN A 1 248 ? 256.408 241.586 259.143 1.00 26.92  ? 248 ASN A C   1 
ATOM   1739  O  O   . ASN A 1 248 ? 256.434 241.897 257.949 1.00 31.98  ? 248 ASN A O   1 
ATOM   1740  C  CB  . ASN A 1 248 ? 257.844 243.362 260.178 1.00 26.84  ? 248 ASN A CB  1 
ATOM   1741  C  CG  . ASN A 1 248 ? 258.944 243.688 261.164 1.00 30.83  ? 248 ASN A CG  1 
ATOM   1742  O  OD1 . ASN A 1 248 ? 258.762 243.574 262.374 1.00 34.99  ? 248 ASN A OD1 1 
ATOM   1743  N  ND2 . ASN A 1 248 ? 260.096 244.097 260.650 1.00 32.27  ? 248 ASN A ND2 1 
ATOM   1744  N  N   . THR A 1 249 ? 255.358 241.018 259.727 1.00 25.58  ? 249 THR A N   1 
ATOM   1745  C  CA  . THR A 1 249 ? 254.137 240.679 259.014 1.00 27.18  ? 249 THR A CA  1 
ATOM   1746  C  C   . THR A 1 249 ? 253.024 241.636 259.415 1.00 26.24  ? 249 THR A C   1 
ATOM   1747  O  O   . THR A 1 249 ? 252.842 241.926 260.600 1.00 27.65  ? 249 THR A O   1 
ATOM   1748  C  CB  . THR A 1 249 ? 253.711 239.239 259.307 1.00 33.09  ? 249 THR A CB  1 
ATOM   1749  O  OG1 . THR A 1 249 ? 254.839 238.368 259.162 1.00 41.87  ? 249 THR A OG1 1 
ATOM   1750  C  CG2 . THR A 1 249 ? 252.612 238.804 258.356 1.00 29.64  ? 249 THR A CG2 1 
ATOM   1751  N  N   . TYR A 1 250 ? 252.280 242.126 258.426 1.00 26.84  ? 250 TYR A N   1 
ATOM   1752  C  CA  . TYR A 1 250 ? 251.165 243.026 258.669 1.00 23.61  ? 250 TYR A CA  1 
ATOM   1753  C  C   . TYR A 1 250 ? 249.944 242.556 257.896 1.00 24.45  ? 250 TYR A C   1 
ATOM   1754  O  O   . TYR A 1 250 ? 250.056 242.002 256.798 1.00 30.36  ? 250 TYR A O   1 
ATOM   1755  C  CB  . TYR A 1 250 ? 251.501 244.471 258.271 1.00 23.62  ? 250 TYR A CB  1 
ATOM   1756  C  CG  . TYR A 1 250 ? 252.793 244.992 258.853 1.00 25.42  ? 250 TYR A CG  1 
ATOM   1757  C  CD1 . TYR A 1 250 ? 252.822 245.580 260.108 1.00 28.59  ? 250 TYR A CD1 1 
ATOM   1758  C  CD2 . TYR A 1 250 ? 253.983 244.902 258.145 1.00 25.76  ? 250 TYR A CD2 1 
ATOM   1759  C  CE1 . TYR A 1 250 ? 253.997 246.058 260.645 1.00 29.47  ? 250 TYR A CE1 1 
ATOM   1760  C  CE2 . TYR A 1 250 ? 255.164 245.377 258.675 1.00 25.78  ? 250 TYR A CE2 1 
ATOM   1761  C  CZ  . TYR A 1 250 ? 255.165 245.955 259.924 1.00 30.17  ? 250 TYR A CZ  1 
ATOM   1762  O  OH  . TYR A 1 250 ? 256.341 246.431 260.454 1.00 33.25  ? 250 TYR A OH  1 
ATOM   1763  N  N   . ILE A 1 251 ? 248.776 242.771 258.495 1.00 26.32  ? 251 ILE A N   1 
ATOM   1764  C  CA  . ILE A 1 251 ? 247.483 242.558 257.854 1.00 25.80  ? 251 ILE A CA  1 
ATOM   1765  C  C   . ILE A 1 251 ? 246.691 243.835 258.100 1.00 23.71  ? 251 ILE A C   1 
ATOM   1766  O  O   . ILE A 1 251 ? 246.151 244.040 259.192 1.00 27.53  ? 251 ILE A O   1 
ATOM   1767  C  CB  . ILE A 1 251 ? 246.745 241.330 258.396 1.00 28.36  ? 251 ILE A CB  1 
ATOM   1768  C  CG1 . ILE A 1 251 ? 247.665 240.108 258.383 1.00 28.53  ? 251 ILE A CG1 1 
ATOM   1769  C  CG2 . ILE A 1 251 ? 245.491 241.061 257.579 1.00 29.47  ? 251 ILE A CG2 1 
ATOM   1770  C  CD1 . ILE A 1 251 ? 246.970 238.817 258.743 1.00 32.78  ? 251 ILE A CD1 1 
ATOM   1771  N  N   . VAL A 1 252 ? 246.615 244.689 257.092 1.00 22.63  ? 252 VAL A N   1 
ATOM   1772  C  CA  . VAL A 1 252 ? 246.128 246.059 257.236 1.00 22.59  ? 252 VAL A CA  1 
ATOM   1773  C  C   . VAL A 1 252 ? 244.839 246.203 256.440 1.00 23.39  ? 252 VAL A C   1 
ATOM   1774  O  O   . VAL A 1 252 ? 244.808 245.828 255.264 1.00 22.70  ? 252 VAL A O   1 
ATOM   1775  C  CB  . VAL A 1 252 ? 247.171 247.087 256.758 1.00 23.61  ? 252 VAL A CB  1 
ATOM   1776  C  CG1 . VAL A 1 252 ? 246.732 248.497 257.114 1.00 19.55  ? 252 VAL A CG1 1 
ATOM   1777  C  CG2 . VAL A 1 252 ? 248.534 246.777 257.353 1.00 21.07  ? 252 VAL A CG2 1 
ATOM   1778  N  N   . PRO A 1 253 ? 243.765 246.729 257.031 1.00 26.56  ? 253 PRO A N   1 
ATOM   1779  C  CA  . PRO A 1 253 ? 242.577 247.086 256.240 1.00 22.85  ? 253 PRO A CA  1 
ATOM   1780  C  C   . PRO A 1 253 ? 242.874 248.322 255.404 1.00 21.49  ? 253 PRO A C   1 
ATOM   1781  O  O   . PRO A 1 253 ? 243.179 249.388 255.941 1.00 20.79  ? 253 PRO A O   1 
ATOM   1782  C  CB  . PRO A 1 253 ? 241.504 247.360 257.303 1.00 20.13  ? 253 PRO A CB  1 
ATOM   1783  C  CG  . PRO A 1 253 ? 242.099 246.933 258.614 1.00 21.09  ? 253 PRO A CG  1 
ATOM   1784  C  CD  . PRO A 1 253 ? 243.579 247.002 258.462 1.00 24.30  ? 253 PRO A CD  1 
ATOM   1785  N  N   . ILE A 1 254 ? 242.781 248.176 254.083 1.00 23.15  ? 254 ILE A N   1 
ATOM   1786  C  CA  . ILE A 1 254 ? 243.323 249.160 253.153 1.00 19.93  ? 254 ILE A CA  1 
ATOM   1787  C  C   . ILE A 1 254 ? 242.251 249.998 252.478 1.00 22.20  ? 254 ILE A C   1 
ATOM   1788  O  O   . ILE A 1 254 ? 242.588 250.835 251.629 1.00 23.43  ? 254 ILE A O   1 
ATOM   1789  C  CB  . ILE A 1 254 ? 244.220 248.487 252.097 1.00 17.67  ? 254 ILE A CB  1 
ATOM   1790  C  CG1 . ILE A 1 254 ? 243.531 247.254 251.506 1.00 17.79  ? 254 ILE A CG1 1 
ATOM   1791  C  CG2 . ILE A 1 254 ? 245.562 248.113 252.700 1.00 18.60  ? 254 ILE A CG2 1 
ATOM   1792  C  CD1 . ILE A 1 254 ? 242.717 247.541 250.268 1.00 18.75  ? 254 ILE A CD1 1 
ATOM   1793  N  N   . TYR A 1 255 ? 240.982 249.819 252.822 1.00 23.54  ? 255 TYR A N   1 
ATOM   1794  C  CA  . TYR A 1 255 ? 239.946 250.630 252.200 1.00 22.09  ? 255 TYR A CA  1 
ATOM   1795  C  C   . TYR A 1 255 ? 239.992 252.055 252.750 1.00 24.98  ? 255 TYR A C   1 
ATOM   1796  O  O   . TYR A 1 255 ? 240.134 252.250 253.960 1.00 27.48  ? 255 TYR A O   1 
ATOM   1797  C  CB  . TYR A 1 255 ? 238.566 250.026 252.432 1.00 24.81  ? 255 TYR A CB  1 
ATOM   1798  C  CG  . TYR A 1 255 ? 237.552 250.478 251.410 1.00 26.18  ? 255 TYR A CG  1 
ATOM   1799  C  CD1 . TYR A 1 255 ? 237.430 249.823 250.194 1.00 29.43  ? 255 TYR A CD1 1 
ATOM   1800  C  CD2 . TYR A 1 255 ? 236.734 251.570 251.651 1.00 26.21  ? 255 TYR A CD2 1 
ATOM   1801  C  CE1 . TYR A 1 255 ? 236.512 250.236 249.251 1.00 28.93  ? 255 TYR A CE1 1 
ATOM   1802  C  CE2 . TYR A 1 255 ? 235.813 251.991 250.715 1.00 24.92  ? 255 TYR A CE2 1 
ATOM   1803  C  CZ  . TYR A 1 255 ? 235.706 251.320 249.517 1.00 31.69  ? 255 TYR A CZ  1 
ATOM   1804  O  OH  . TYR A 1 255 ? 234.788 251.736 248.582 1.00 36.03  ? 255 TYR A OH  1 
ATOM   1805  N  N   . PRO A 1 256 ? 239.874 253.066 251.890 1.00 22.68  ? 256 PRO A N   1 
ATOM   1806  C  CA  . PRO A 1 256 ? 239.997 254.451 252.359 1.00 22.49  ? 256 PRO A CA  1 
ATOM   1807  C  C   . PRO A 1 256 ? 238.933 254.800 253.387 1.00 24.73  ? 256 PRO A C   1 
ATOM   1808  O  O   . PRO A 1 256 ? 237.808 254.298 253.350 1.00 29.97  ? 256 PRO A O   1 
ATOM   1809  C  CB  . PRO A 1 256 ? 239.824 255.278 251.081 1.00 20.94  ? 256 PRO A CB  1 
ATOM   1810  C  CG  . PRO A 1 256 ? 240.144 254.352 249.971 1.00 19.91  ? 256 PRO A CG  1 
ATOM   1811  C  CD  . PRO A 1 256 ? 239.757 252.980 250.425 1.00 18.43  ? 256 PRO A CD  1 
ATOM   1812  N  N   . ASP A 1 257 ? 239.309 255.671 254.320 1.00 25.48  ? 257 ASP A N   1 
ATOM   1813  C  CA  . ASP A 1 257 ? 238.382 256.210 255.313 1.00 27.06  ? 257 ASP A CA  1 
ATOM   1814  C  C   . ASP A 1 257 ? 237.666 257.396 254.682 1.00 25.91  ? 257 ASP A C   1 
ATOM   1815  O  O   . ASP A 1 257 ? 238.140 258.531 254.718 1.00 29.93  ? 257 ASP A O   1 
ATOM   1816  C  CB  . ASP A 1 257 ? 239.122 256.612 256.582 1.00 27.29  ? 257 ASP A CB  1 
ATOM   1817  C  CG  . ASP A 1 257 ? 238.221 257.285 257.596 1.00 35.50  ? 257 ASP A CG  1 
ATOM   1818  O  OD1 . ASP A 1 257 ? 237.060 256.850 257.743 1.00 37.57  ? 257 ASP A OD1 1 
ATOM   1819  O  OD2 . ASP A 1 257 ? 238.671 258.251 258.246 1.00 34.24  ? 257 ASP A OD2 1 
ATOM   1820  N  N   . GLU A 1 258 ? 236.503 257.128 254.086 1.00 28.62  ? 258 GLU A N   1 
ATOM   1821  C  CA  . GLU A 1 258 ? 235.770 258.175 253.385 1.00 24.56  ? 258 GLU A CA  1 
ATOM   1822  C  C   . GLU A 1 258 ? 235.070 259.132 254.336 1.00 26.44  ? 258 GLU A C   1 
ATOM   1823  O  O   . GLU A 1 258 ? 234.695 260.233 253.923 1.00 28.32  ? 258 GLU A O   1 
ATOM   1824  C  CB  . GLU A 1 258 ? 234.754 257.551 252.430 1.00 24.51  ? 258 GLU A CB  1 
ATOM   1825  C  CG  . GLU A 1 258 ? 235.359 256.565 251.451 1.00 29.02  ? 258 GLU A CG  1 
ATOM   1826  C  CD  . GLU A 1 258 ? 234.346 256.041 250.457 1.00 39.10  ? 258 GLU A CD  1 
ATOM   1827  O  OE1 . GLU A 1 258 ? 233.693 255.019 250.756 1.00 34.51  ? 258 GLU A OE1 1 
ATOM   1828  O  OE2 . GLU A 1 258 ? 234.201 256.651 249.378 1.00 44.83  ? 258 GLU A OE2 1 
ATOM   1829  N  N   . THR A 1 259 ? 234.893 258.744 255.599 1.00 28.27  ? 259 THR A N   1 
ATOM   1830  C  CA  . THR A 1 259 ? 234.236 259.606 256.572 1.00 24.39  ? 259 THR A CA  1 
ATOM   1831  C  C   . THR A 1 259 ? 235.108 260.774 257.012 1.00 23.11  ? 259 THR A C   1 
ATOM   1832  O  O   . THR A 1 259 ? 234.612 261.656 257.722 1.00 28.33  ? 259 THR A O   1 
ATOM   1833  C  CB  . THR A 1 259 ? 233.812 258.786 257.789 1.00 27.49  ? 259 THR A CB  1 
ATOM   1834  O  OG1 . THR A 1 259 ? 234.973 258.375 258.518 1.00 35.04  ? 259 THR A OG1 1 
ATOM   1835  C  CG2 . THR A 1 259 ? 233.033 257.558 257.352 1.00 21.14  ? 259 THR A CG2 1 
ATOM   1836  N  N   . CYS A 1 260 ? 236.380 260.809 256.607 1.00 24.26  ? 260 CYS A N   1 
ATOM   1837  C  CA  . CYS A 1 260 ? 237.259 261.901 257.013 1.00 22.33  ? 260 CYS A CA  1 
ATOM   1838  C  C   . CYS A 1 260 ? 236.649 263.257 256.682 1.00 25.34  ? 260 CYS A C   1 
ATOM   1839  O  O   . CYS A 1 260 ? 236.682 264.180 257.505 1.00 27.22  ? 260 CYS A O   1 
ATOM   1840  C  CB  . CYS A 1 260 ? 238.631 261.748 256.350 1.00 25.77  ? 260 CYS A CB  1 
ATOM   1841  S  SG  . CYS A 1 260 ? 238.607 261.592 254.549 1.00 29.47  ? 260 CYS A SG  1 
ATOM   1842  N  N   . TRP A 1 261 ? 236.064 263.389 255.488 1.00 23.71  ? 261 TRP A N   1 
ATOM   1843  C  CA  . TRP A 1 261 ? 235.440 264.648 255.096 1.00 23.52  ? 261 TRP A CA  1 
ATOM   1844  C  C   . TRP A 1 261 ? 234.458 265.134 256.153 1.00 24.14  ? 261 TRP A C   1 
ATOM   1845  O  O   . TRP A 1 261 ? 234.405 266.330 256.461 1.00 28.93  ? 261 TRP A O   1 
ATOM   1846  C  CB  . TRP A 1 261 ? 234.723 264.484 253.757 1.00 21.42  ? 261 TRP A CB  1 
ATOM   1847  C  CG  . TRP A 1 261 ? 235.626 264.157 252.615 1.00 21.00  ? 261 TRP A CG  1 
ATOM   1848  C  CD1 . TRP A 1 261 ? 235.853 262.925 252.085 1.00 21.93  ? 261 TRP A CD1 1 
ATOM   1849  C  CD2 . TRP A 1 261 ? 236.399 265.078 251.837 1.00 20.68  ? 261 TRP A CD2 1 
ATOM   1850  N  NE1 . TRP A 1 261 ? 236.732 263.015 251.036 1.00 21.50  ? 261 TRP A NE1 1 
ATOM   1851  C  CE2 . TRP A 1 261 ? 237.082 264.327 250.862 1.00 20.43  ? 261 TRP A CE2 1 
ATOM   1852  C  CE3 . TRP A 1 261 ? 236.587 266.462 251.875 1.00 18.61  ? 261 TRP A CE3 1 
ATOM   1853  C  CZ2 . TRP A 1 261 ? 237.936 264.912 249.934 1.00 19.28  ? 261 TRP A CZ2 1 
ATOM   1854  C  CZ3 . TRP A 1 261 ? 237.434 267.041 250.953 1.00 16.26  ? 261 TRP A CZ3 1 
ATOM   1855  C  CH2 . TRP A 1 261 ? 238.099 266.268 249.995 1.00 18.65  ? 261 TRP A CH2 1 
ATOM   1856  N  N   . VAL A 1 262 ? 233.657 264.222 256.706 1.00 26.03  ? 262 VAL A N   1 
ATOM   1857  C  CA  . VAL A 1 262 ? 232.693 264.610 257.729 1.00 25.08  ? 262 VAL A CA  1 
ATOM   1858  C  C   . VAL A 1 262 ? 233.400 264.941 259.037 1.00 24.10  ? 262 VAL A C   1 
ATOM   1859  O  O   . VAL A 1 262 ? 233.029 265.891 259.735 1.00 28.60  ? 262 VAL A O   1 
ATOM   1860  C  CB  . VAL A 1 262 ? 231.640 263.504 257.920 1.00 27.16  ? 262 VAL A CB  1 
ATOM   1861  C  CG1 . VAL A 1 262 ? 230.935 263.666 259.256 1.00 26.65  ? 262 VAL A CG1 1 
ATOM   1862  C  CG2 . VAL A 1 262 ? 230.640 263.520 256.777 1.00 24.54  ? 262 VAL A CG2 1 
ATOM   1863  N  N   . ASN A 1 263 ? 234.428 264.168 259.391 1.00 25.00  ? 263 ASN A N   1 
ATOM   1864  C  CA  . ASN A 1 263 ? 235.031 264.295 260.711 1.00 22.15  ? 263 ASN A CA  1 
ATOM   1865  C  C   . ASN A 1 263 ? 236.032 265.437 260.802 1.00 25.05  ? 263 ASN A C   1 
ATOM   1866  O  O   . ASN A 1 263 ? 236.253 265.961 261.898 1.00 28.89  ? 263 ASN A O   1 
ATOM   1867  C  CB  . ASN A 1 263 ? 235.708 262.982 261.106 1.00 21.65  ? 263 ASN A CB  1 
ATOM   1868  C  CG  . ASN A 1 263 ? 234.710 261.908 261.489 1.00 28.45  ? 263 ASN A CG  1 
ATOM   1869  O  OD1 . ASN A 1 263 ? 233.916 262.086 262.411 1.00 34.23  ? 263 ASN A OD1 1 
ATOM   1870  N  ND2 . ASN A 1 263 ? 234.746 260.786 260.783 1.00 27.00  ? 263 ASN A ND2 1 
ATOM   1871  N  N   . ASP A 1 264 ? 236.640 265.834 259.685 1.00 26.55  ? 264 ASP A N   1 
ATOM   1872  C  CA  . ASP A 1 264 ? 237.612 266.918 259.718 1.00 28.23  ? 264 ASP A CA  1 
ATOM   1873  C  C   . ASP A 1 264 ? 236.952 268.282 259.873 1.00 29.90  ? 264 ASP A C   1 
ATOM   1874  O  O   . ASP A 1 264 ? 237.559 269.196 260.441 1.00 35.47  ? 264 ASP A O   1 
ATOM   1875  C  CB  . ASP A 1 264 ? 238.471 266.894 258.452 1.00 26.39  ? 264 ASP A CB  1 
ATOM   1876  C  CG  . ASP A 1 264 ? 239.433 265.722 258.421 1.00 31.11  ? 264 ASP A CG  1 
ATOM   1877  O  OD1 . ASP A 1 264 ? 239.754 265.186 259.500 1.00 35.17  ? 264 ASP A OD1 1 
ATOM   1878  O  OD2 . ASP A 1 264 ? 239.867 265.339 257.317 1.00 33.00  ? 264 ASP A OD2 1 
ATOM   1879  N  N   . PHE A 1 265 ? 235.719 268.439 259.393 1.00 25.81  ? 265 PHE A N   1 
ATOM   1880  C  CA  . PHE A 1 265 ? 235.071 269.746 259.282 1.00 27.36  ? 265 PHE A CA  1 
ATOM   1881  C  C   . PHE A 1 265 ? 233.690 269.710 259.922 1.00 31.64  ? 265 PHE A C   1 
ATOM   1882  O  O   . PHE A 1 265 ? 232.677 269.526 259.236 1.00 32.80  ? 265 PHE A O   1 
ATOM   1883  C  CB  . PHE A 1 265 ? 234.985 270.180 257.820 1.00 24.03  ? 265 PHE A CB  1 
ATOM   1884  C  CG  . PHE A 1 265 ? 236.272 270.018 257.076 1.00 28.08  ? 265 PHE A CG  1 
ATOM   1885  C  CD1 . PHE A 1 265 ? 237.289 270.945 257.216 1.00 25.31  ? 265 PHE A CD1 1 
ATOM   1886  C  CD2 . PHE A 1 265 ? 236.473 268.929 256.249 1.00 27.22  ? 265 PHE A CD2 1 
ATOM   1887  C  CE1 . PHE A 1 265 ? 238.478 270.792 256.538 1.00 23.61  ? 265 PHE A CE1 1 
ATOM   1888  C  CE2 . PHE A 1 265 ? 237.659 268.771 255.568 1.00 27.28  ? 265 PHE A CE2 1 
ATOM   1889  C  CZ  . PHE A 1 265 ? 238.663 269.704 255.713 1.00 24.32  ? 265 PHE A CZ  1 
ATOM   1890  N  N   . PRO A 1 266 ? 233.613 269.887 261.240 1.00 29.72  ? 266 PRO A N   1 
ATOM   1891  C  CA  . PRO A 1 266 ? 232.303 270.009 261.888 1.00 28.61  ? 266 PRO A CA  1 
ATOM   1892  C  C   . PRO A 1 266 ? 231.556 271.243 261.403 1.00 27.38  ? 266 PRO A C   1 
ATOM   1893  O  O   . PRO A 1 266 ? 232.151 272.274 261.084 1.00 31.02  ? 266 PRO A O   1 
ATOM   1894  C  CB  . PRO A 1 266 ? 232.648 270.117 263.379 1.00 25.84  ? 266 PRO A CB  1 
ATOM   1895  C  CG  . PRO A 1 266 ? 234.065 269.667 263.497 1.00 28.19  ? 266 PRO A CG  1 
ATOM   1896  C  CD  . PRO A 1 266 ? 234.722 269.987 262.200 1.00 23.45  ? 266 PRO A CD  1 
ATOM   1897  N  N   . ASN A 1 267 ? 230.230 271.123 261.348 1.00 28.42  ? 267 ASN A N   1 
ATOM   1898  C  CA  . ASN A 1 267 ? 229.352 272.232 260.976 1.00 26.98  ? 267 ASN A CA  1 
ATOM   1899  C  C   . ASN A 1 267 ? 229.551 272.642 259.518 1.00 27.26  ? 267 ASN A C   1 
ATOM   1900  O  O   . ASN A 1 267 ? 229.551 273.828 259.187 1.00 28.92  ? 267 ASN A O   1 
ATOM   1901  C  CB  . ASN A 1 267 ? 229.548 273.430 261.907 1.00 25.15  ? 267 ASN A CB  1 
ATOM   1902  C  CG  . ASN A 1 267 ? 229.089 273.147 263.320 1.00 30.75  ? 267 ASN A CG  1 
ATOM   1903  O  OD1 . ASN A 1 267 ? 228.040 272.542 263.534 1.00 35.74  ? 267 ASN A OD1 1 
ATOM   1904  N  ND2 . ASN A 1 267 ? 229.875 273.584 264.296 1.00 34.54  ? 267 ASN A ND2 1 
ATOM   1905  N  N   . ALA A 1 268 ? 229.712 271.655 258.641 1.00 26.24  ? 268 ALA A N   1 
ATOM   1906  C  CA  . ALA A 1 268 ? 229.880 271.897 257.218 1.00 23.53  ? 268 ALA A CA  1 
ATOM   1907  C  C   . ALA A 1 268 ? 229.130 270.830 256.436 1.00 25.91  ? 268 ALA A C   1 
ATOM   1908  O  O   . ALA A 1 268 ? 228.866 269.735 256.937 1.00 32.66  ? 268 ALA A O   1 
ATOM   1909  C  CB  . ALA A 1 268 ? 231.360 271.908 256.814 1.00 25.29  ? 268 ALA A CB  1 
ATOM   1910  N  N   . ARG A 1 269 ? 228.785 271.165 255.192 1.00 26.05  ? 269 ARG A N   1 
ATOM   1911  C  CA  . ARG A 1 269 ? 228.132 270.219 254.289 1.00 25.26  ? 269 ARG A CA  1 
ATOM   1912  C  C   . ARG A 1 269 ? 229.211 269.537 253.454 1.00 27.83  ? 269 ARG A C   1 
ATOM   1913  O  O   . ARG A 1 269 ? 229.443 269.856 252.287 1.00 31.25  ? 269 ARG A O   1 
ATOM   1914  C  CB  . ARG A 1 269 ? 227.102 270.926 253.419 1.00 23.61  ? 269 ARG A CB  1 
ATOM   1915  C  CG  . ARG A 1 269 ? 225.807 271.252 254.134 1.00 27.50  ? 269 ARG A CG  1 
ATOM   1916  C  CD  . ARG A 1 269 ? 224.698 271.574 253.149 1.00 29.28  ? 269 ARG A CD  1 
ATOM   1917  N  NE  . ARG A 1 269 ? 224.506 270.507 252.175 1.00 27.19  ? 269 ARG A NE  1 
ATOM   1918  C  CZ  . ARG A 1 269 ? 223.580 269.564 252.273 1.00 31.57  ? 269 ARG A CZ  1 
ATOM   1919  N  NH1 . ARG A 1 269 ? 222.744 269.521 253.297 1.00 33.61  ? 269 ARG A NH1 1 
ATOM   1920  N  NH2 . ARG A 1 269 ? 223.492 268.640 251.322 1.00 30.66  ? 269 ARG A NH2 1 
ATOM   1921  N  N   . THR A 1 270 ? 229.886 268.576 254.080 1.00 29.02  ? 270 THR A N   1 
ATOM   1922  C  CA  . THR A 1 270 ? 230.963 267.839 253.437 1.00 27.11  ? 270 THR A CA  1 
ATOM   1923  C  C   . THR A 1 270 ? 230.654 266.360 253.257 1.00 25.86  ? 270 THR A C   1 
ATOM   1924  O  O   . THR A 1 270 ? 231.517 265.620 252.773 1.00 29.65  ? 270 THR A O   1 
ATOM   1925  C  CB  . THR A 1 270 ? 232.265 267.997 254.234 1.00 26.64  ? 270 THR A CB  1 
ATOM   1926  O  OG1 . THR A 1 270 ? 232.040 267.629 255.599 1.00 27.93  ? 270 THR A OG1 1 
ATOM   1927  C  CG2 . THR A 1 270 ? 232.745 269.434 254.181 1.00 26.58  ? 270 THR A CG2 1 
ATOM   1928  N  N   . GLU A 1 271 ? 229.457 265.907 253.635 1.00 27.54  ? 271 GLU A N   1 
ATOM   1929  C  CA  . GLU A 1 271 ? 229.090 264.510 253.436 1.00 27.43  ? 271 GLU A CA  1 
ATOM   1930  C  C   . GLU A 1 271 ? 228.990 264.148 251.960 1.00 26.30  ? 271 GLU A C   1 
ATOM   1931  O  O   . GLU A 1 271 ? 229.132 262.970 251.610 1.00 27.09  ? 271 GLU A O   1 
ATOM   1932  C  CB  . GLU A 1 271 ? 227.770 264.217 254.150 1.00 22.86  ? 271 GLU A CB  1 
ATOM   1933  C  CG  . GLU A 1 271 ? 226.596 265.032 253.633 1.00 34.82  ? 271 GLU A CG  1 
ATOM   1934  C  CD  . GLU A 1 271 ? 226.295 266.245 254.494 1.00 40.46  ? 271 GLU A CD  1 
ATOM   1935  O  OE1 . GLU A 1 271 ? 227.201 266.707 255.221 1.00 36.11  ? 271 GLU A OE1 1 
ATOM   1936  O  OE2 . GLU A 1 271 ? 225.151 266.739 254.443 1.00 43.05  ? 271 GLU A OE2 1 
ATOM   1937  N  N   . ILE A 1 272 ? 228.762 265.133 251.090 1.00 28.19  ? 272 ILE A N   1 
ATOM   1938  C  CA  . ILE A 1 272 ? 228.759 264.871 249.654 1.00 27.73  ? 272 ILE A CA  1 
ATOM   1939  C  C   . ILE A 1 272 ? 230.100 264.300 249.219 1.00 27.08  ? 272 ILE A C   1 
ATOM   1940  O  O   . ILE A 1 272 ? 230.164 263.397 248.376 1.00 29.19  ? 272 ILE A O   1 
ATOM   1941  C  CB  . ILE A 1 272 ? 228.411 266.155 248.876 1.00 26.40  ? 272 ILE A CB  1 
ATOM   1942  C  CG1 . ILE A 1 272 ? 228.285 265.856 247.382 1.00 29.30  ? 272 ILE A CG1 1 
ATOM   1943  C  CG2 . ILE A 1 272 ? 229.462 267.226 249.114 1.00 23.07  ? 272 ILE A CG2 1 
ATOM   1944  C  CD1 . ILE A 1 272 ? 227.213 264.853 247.050 1.00 31.75  ? 272 ILE A CD1 1 
ATOM   1945  N  N   . TYR A 1 273 ? 231.192 264.818 249.781 1.00 26.03  ? 273 TYR A N   1 
ATOM   1946  C  CA  . TYR A 1 273 ? 232.510 264.290 249.450 1.00 21.21  ? 273 TYR A CA  1 
ATOM   1947  C  C   . TYR A 1 273 ? 232.730 262.926 250.090 1.00 22.53  ? 273 TYR A C   1 
ATOM   1948  O  O   . TYR A 1 273 ? 233.385 262.058 249.504 1.00 28.90  ? 273 TYR A O   1 
ATOM   1949  C  CB  . TYR A 1 273 ? 233.588 265.280 249.885 1.00 19.08  ? 273 TYR A CB  1 
ATOM   1950  C  CG  . TYR A 1 273 ? 233.310 266.685 249.413 1.00 23.83  ? 273 TYR A CG  1 
ATOM   1951  C  CD1 . TYR A 1 273 ? 233.019 266.944 248.082 1.00 23.52  ? 273 TYR A CD1 1 
ATOM   1952  C  CD2 . TYR A 1 273 ? 233.318 267.750 250.300 1.00 27.02  ? 273 TYR A CD2 1 
ATOM   1953  C  CE1 . TYR A 1 273 ? 232.756 268.224 247.646 1.00 19.45  ? 273 TYR A CE1 1 
ATOM   1954  C  CE2 . TYR A 1 273 ? 233.055 269.034 249.874 1.00 27.14  ? 273 TYR A CE2 1 
ATOM   1955  C  CZ  . TYR A 1 273 ? 232.774 269.265 248.546 1.00 25.88  ? 273 TYR A CZ  1 
ATOM   1956  O  OH  . TYR A 1 273 ? 232.513 270.543 248.115 1.00 29.71  ? 273 TYR A OH  1 
ATOM   1957  N  N   . THR A 1 274 ? 232.190 262.718 251.291 1.00 22.90  ? 274 THR A N   1 
ATOM   1958  C  CA  . THR A 1 274 ? 232.239 261.397 251.900 1.00 24.29  ? 274 THR A CA  1 
ATOM   1959  C  C   . THR A 1 274 ? 231.504 260.363 251.062 1.00 25.34  ? 274 THR A C   1 
ATOM   1960  O  O   . THR A 1 274 ? 231.805 259.168 251.160 1.00 33.14  ? 274 THR A O   1 
ATOM   1961  C  CB  . THR A 1 274 ? 231.645 261.441 253.310 1.00 22.04  ? 274 THR A CB  1 
ATOM   1962  O  OG1 . THR A 1 274 ? 232.568 262.078 254.200 1.00 25.96  ? 274 THR A OG1 1 
ATOM   1963  C  CG2 . THR A 1 274 ? 231.359 260.038 253.812 1.00 14.48  ? 274 THR A CG2 1 
ATOM   1964  N  N   . ARG A 1 275 ? 230.554 260.795 250.236 1.00 24.99  ? 275 ARG A N   1 
ATOM   1965  C  CA  . ARG A 1 275 ? 229.784 259.879 249.406 1.00 25.17  ? 275 ARG A CA  1 
ATOM   1966  C  C   . ARG A 1 275 ? 230.326 259.725 247.991 1.00 29.05  ? 275 ARG A C   1 
ATOM   1967  O  O   . ARG A 1 275 ? 230.199 258.642 247.412 1.00 34.06  ? 275 ARG A O   1 
ATOM   1968  C  CB  . ARG A 1 275 ? 228.324 260.337 249.333 1.00 31.12  ? 275 ARG A CB  1 
ATOM   1969  C  CG  . ARG A 1 275 ? 227.641 260.430 250.685 1.00 31.46  ? 275 ARG A CG  1 
ATOM   1970  C  CD  . ARG A 1 275 ? 226.197 260.866 250.544 1.00 35.27  ? 275 ARG A CD  1 
ATOM   1971  N  NE  . ARG A 1 275 ? 225.421 259.927 249.744 1.00 43.95  ? 275 ARG A NE  1 
ATOM   1972  C  CZ  . ARG A 1 275 ? 224.315 260.242 249.086 1.00 47.68  ? 275 ARG A CZ  1 
ATOM   1973  N  NH1 . ARG A 1 275 ? 223.823 261.469 249.111 1.00 44.17  ? 275 ARG A NH1 1 
ATOM   1974  N  NH2 . ARG A 1 275 ? 223.689 259.304 248.382 1.00 48.90  ? 275 ARG A NH2 1 
ATOM   1975  N  N   . MET A 1 276 ? 230.931 260.769 247.415 1.00 27.02  ? 276 MET A N   1 
ATOM   1976  C  CA  . MET A 1 276 ? 231.256 260.773 245.994 1.00 29.20  ? 276 MET A CA  1 
ATOM   1977  C  C   . MET A 1 276 ? 232.740 260.811 245.660 1.00 27.99  ? 276 MET A C   1 
ATOM   1978  O  O   . MET A 1 276 ? 233.108 260.371 244.567 1.00 29.98  ? 276 MET A O   1 
ATOM   1979  C  CB  . MET A 1 276 ? 230.593 261.971 245.295 1.00 32.91  ? 276 MET A CB  1 
ATOM   1980  C  CG  . MET A 1 276 ? 229.248 262.372 245.861 1.00 42.81  ? 276 MET A CG  1 
ATOM   1981  S  SD  . MET A 1 276 ? 227.863 261.589 245.021 1.00 72.72  ? 276 MET A SD  1 
ATOM   1982  C  CE  . MET A 1 276 ? 226.624 261.659 246.312 1.00 54.88  ? 276 MET A CE  1 
ATOM   1983  N  N   . TYR A 1 277 ? 233.599 261.321 246.545 1.00 23.98  ? 277 TYR A N   1 
ATOM   1984  C  CA  . TYR A 1 277 ? 234.962 261.649 246.130 1.00 25.75  ? 277 TYR A CA  1 
ATOM   1985  C  C   . TYR A 1 277 ? 235.713 260.417 245.635 1.00 25.39  ? 277 TYR A C   1 
ATOM   1986  O  O   . TYR A 1 277 ? 236.371 260.458 244.590 1.00 27.42  ? 277 TYR A O   1 
ATOM   1987  C  CB  . TYR A 1 277 ? 235.720 262.316 247.278 1.00 21.86  ? 277 TYR A CB  1 
ATOM   1988  C  CG  . TYR A 1 277 ? 237.087 262.826 246.883 1.00 20.57  ? 277 TYR A CG  1 
ATOM   1989  C  CD1 . TYR A 1 277 ? 237.226 263.994 246.146 1.00 21.03  ? 277 TYR A CD1 1 
ATOM   1990  C  CD2 . TYR A 1 277 ? 238.238 262.138 247.239 1.00 20.28  ? 277 TYR A CD2 1 
ATOM   1991  C  CE1 . TYR A 1 277 ? 238.471 264.465 245.782 1.00 20.14  ? 277 TYR A CE1 1 
ATOM   1992  C  CE2 . TYR A 1 277 ? 239.487 262.601 246.880 1.00 17.31  ? 277 TYR A CE2 1 
ATOM   1993  C  CZ  . TYR A 1 277 ? 239.598 263.764 246.150 1.00 22.04  ? 277 TYR A CZ  1 
ATOM   1994  O  OH  . TYR A 1 277 ? 240.839 264.232 245.788 1.00 24.73  ? 277 TYR A OH  1 
ATOM   1995  N  N   . PHE A 1 278 ? 235.630 259.311 246.372 1.00 25.76  ? 278 PHE A N   1 
ATOM   1996  C  CA  . PHE A 1 278 ? 236.323 258.088 245.989 1.00 22.83  ? 278 PHE A CA  1 
ATOM   1997  C  C   . PHE A 1 278 ? 235.500 257.199 245.066 1.00 27.36  ? 278 PHE A C   1 
ATOM   1998  O  O   . PHE A 1 278 ? 236.020 256.192 244.575 1.00 33.73  ? 278 PHE A O   1 
ATOM   1999  C  CB  . PHE A 1 278 ? 236.727 257.296 247.240 1.00 24.24  ? 278 PHE A CB  1 
ATOM   2000  C  CG  . PHE A 1 278 ? 237.578 256.089 246.950 1.00 25.67  ? 278 PHE A CG  1 
ATOM   2001  C  CD1 . PHE A 1 278 ? 238.794 256.222 246.301 1.00 24.04  ? 278 PHE A CD1 1 
ATOM   2002  C  CD2 . PHE A 1 278 ? 237.158 254.823 247.320 1.00 23.53  ? 278 PHE A CD2 1 
ATOM   2003  C  CE1 . PHE A 1 278 ? 239.576 255.116 246.030 1.00 22.75  ? 278 PHE A CE1 1 
ATOM   2004  C  CE2 . PHE A 1 278 ? 237.936 253.714 247.052 1.00 23.39  ? 278 PHE A CE2 1 
ATOM   2005  C  CZ  . PHE A 1 278 ? 239.146 253.860 246.407 1.00 21.35  ? 278 PHE A CZ  1 
ATOM   2006  N  N   . ASN A 1 279 ? 234.241 257.547 244.807 1.00 32.48  ? 279 ASN A N   1 
ATOM   2007  C  CA  . ASN A 1 279 ? 233.352 256.713 244.012 1.00 33.04  ? 279 ASN A CA  1 
ATOM   2008  C  C   . ASN A 1 279 ? 232.880 257.375 242.725 1.00 37.48  ? 279 ASN A C   1 
ATOM   2009  O  O   . ASN A 1 279 ? 232.174 256.730 241.941 1.00 45.91  ? 279 ASN A O   1 
ATOM   2010  C  CB  . ASN A 1 279 ? 232.132 256.299 244.846 1.00 34.90  ? 279 ASN A CB  1 
ATOM   2011  C  CG  . ASN A 1 279 ? 232.491 255.993 246.287 1.00 34.55  ? 279 ASN A CG  1 
ATOM   2012  O  OD1 . ASN A 1 279 ? 232.787 254.851 246.635 1.00 36.99  ? 279 ASN A OD1 1 
ATOM   2013  N  ND2 . ASN A 1 279 ? 232.470 257.016 247.132 1.00 29.54  ? 279 ASN A ND2 1 
ATOM   2014  N  N   . HIS A 1 280 ? 233.241 258.629 242.481 1.00 34.42  ? 280 HIS A N   1 
ATOM   2015  C  CA  . HIS A 1 280 ? 232.755 259.257 241.261 1.00 34.86  ? 280 HIS A CA  1 
ATOM   2016  C  C   . HIS A 1 280 ? 233.804 259.180 240.160 1.00 36.82  ? 280 HIS A C   1 
ATOM   2017  O  O   . HIS A 1 280 ? 234.989 259.414 240.413 1.00 38.10  ? 280 HIS A O   1 
ATOM   2018  C  CB  . HIS A 1 280 ? 232.393 260.720 241.515 1.00 36.32  ? 280 HIS A CB  1 
ATOM   2019  C  CG  . HIS A 1 280 ? 231.442 261.290 240.510 1.00 45.09  ? 280 HIS A CG  1 
ATOM   2020  N  ND1 . HIS A 1 280 ? 231.743 261.386 239.169 1.00 44.97  ? 280 HIS A ND1 1 
ATOM   2021  C  CD2 . HIS A 1 280 ? 230.191 261.788 240.650 1.00 52.14  ? 280 HIS A CD2 1 
ATOM   2022  C  CE1 . HIS A 1 280 ? 230.721 261.921 238.527 1.00 46.10  ? 280 HIS A CE1 1 
ATOM   2023  N  NE2 . HIS A 1 280 ? 229.765 262.173 239.403 1.00 55.04  ? 280 HIS A NE2 1 
ATOM   2024  N  N   . PRO A 1 281 ? 233.404 258.847 238.932 1.00 39.90  ? 281 PRO A N   1 
ATOM   2025  C  CA  . PRO A 1 281 ? 234.379 258.820 237.830 1.00 37.36  ? 281 PRO A CA  1 
ATOM   2026  C  C   . PRO A 1 281 ? 234.999 260.172 237.541 1.00 35.16  ? 281 PRO A C   1 
ATOM   2027  O  O   . PRO A 1 281 ? 236.084 260.226 236.950 1.00 38.35  ? 281 PRO A O   1 
ATOM   2028  C  CB  . PRO A 1 281 ? 233.553 258.317 236.639 1.00 41.99  ? 281 PRO A CB  1 
ATOM   2029  C  CG  . PRO A 1 281 ? 232.358 257.663 237.242 1.00 48.23  ? 281 PRO A CG  1 
ATOM   2030  C  CD  . PRO A 1 281 ? 232.070 258.401 238.504 1.00 46.05  ? 281 PRO A CD  1 
ATOM   2031  N  N   . GLY A 1 282 ? 234.345 261.267 237.931 1.00 37.30  ? 282 GLY A N   1 
ATOM   2032  C  CA  . GLY A 1 282 ? 234.910 262.585 237.711 1.00 34.61  ? 282 GLY A CA  1 
ATOM   2033  C  C   . GLY A 1 282 ? 236.071 262.914 238.620 1.00 31.49  ? 282 GLY A C   1 
ATOM   2034  O  O   . GLY A 1 282 ? 236.875 263.790 238.289 1.00 36.17  ? 282 GLY A O   1 
ATOM   2035  N  N   . TYR A 1 283 ? 236.181 262.230 239.754 1.00 29.73  ? 283 TYR A N   1 
ATOM   2036  C  CA  . TYR A 1 283 ? 237.282 262.417 240.686 1.00 25.76  ? 283 TYR A CA  1 
ATOM   2037  C  C   . TYR A 1 283 ? 238.384 261.385 240.496 1.00 24.58  ? 283 TYR A C   1 
ATOM   2038  O  O   . TYR A 1 283 ? 239.253 261.257 241.363 1.00 24.18  ? 283 TYR A O   1 
ATOM   2039  C  CB  . TYR A 1 283 ? 236.766 262.368 242.124 1.00 25.28  ? 283 TYR A CB  1 
ATOM   2040  C  CG  . TYR A 1 283 ? 235.953 263.571 242.540 1.00 25.92  ? 283 TYR A CG  1 
ATOM   2041  C  CD1 . TYR A 1 283 ? 236.504 264.844 242.528 1.00 23.19  ? 283 TYR A CD1 1 
ATOM   2042  C  CD2 . TYR A 1 283 ? 234.636 263.432 242.953 1.00 26.42  ? 283 TYR A CD2 1 
ATOM   2043  C  CE1 . TYR A 1 283 ? 235.767 265.943 242.913 1.00 25.02  ? 283 TYR A CE1 1 
ATOM   2044  C  CE2 . TYR A 1 283 ? 233.891 264.525 243.340 1.00 26.20  ? 283 TYR A CE2 1 
ATOM   2045  C  CZ  . TYR A 1 283 ? 234.461 265.779 243.317 1.00 29.52  ? 283 TYR A CZ  1 
ATOM   2046  O  OH  . TYR A 1 283 ? 233.724 266.874 243.701 1.00 35.08  ? 283 TYR A OH  1 
ATOM   2047  N  N   . ASP A 1 284 ? 238.368 260.648 239.382 1.00 26.18  ? 284 ASP A N   1 
ATOM   2048  C  CA  . ASP A 1 284 ? 239.313 259.551 239.199 1.00 24.16  ? 284 ASP A CA  1 
ATOM   2049  C  C   . ASP A 1 284 ? 240.755 260.042 239.231 1.00 26.24  ? 284 ASP A C   1 
ATOM   2050  O  O   . ASP A 1 284 ? 241.621 259.406 239.842 1.00 25.02  ? 284 ASP A O   1 
ATOM   2051  C  CB  . ASP A 1 284 ? 239.026 258.828 237.884 1.00 25.28  ? 284 ASP A CB  1 
ATOM   2052  C  CG  . ASP A 1 284 ? 238.131 257.622 238.067 1.00 36.53  ? 284 ASP A CG  1 
ATOM   2053  O  OD1 . ASP A 1 284 ? 237.784 257.312 239.223 1.00 34.82  ? 284 ASP A OD1 1 
ATOM   2054  O  OD2 . ASP A 1 284 ? 237.779 256.983 237.055 1.00 46.31  ? 284 ASP A OD2 1 
ATOM   2055  N  N   . ASP A 1 285 ? 241.035 261.168 238.575 1.00 27.67  ? 285 ASP A N   1 
ATOM   2056  C  CA  . ASP A 1 285 ? 242.377 261.726 238.523 1.00 19.26  ? 285 ASP A CA  1 
ATOM   2057  C  C   . ASP A 1 285 ? 242.655 262.694 239.665 1.00 20.37  ? 285 ASP A C   1 
ATOM   2058  O  O   . ASP A 1 285 ? 243.604 263.482 239.583 1.00 26.28  ? 285 ASP A O   1 
ATOM   2059  C  CB  . ASP A 1 285 ? 242.610 262.417 237.179 1.00 23.26  ? 285 ASP A CB  1 
ATOM   2060  C  CG  . ASP A 1 285 ? 242.547 261.455 236.013 1.00 32.16  ? 285 ASP A CG  1 
ATOM   2061  O  OD1 . ASP A 1 285 ? 242.889 260.269 236.202 1.00 33.44  ? 285 ASP A OD1 1 
ATOM   2062  O  OD2 . ASP A 1 285 ? 242.162 261.883 234.906 1.00 40.71  ? 285 ASP A OD2 1 
ATOM   2063  N  N   . TYR A 1 286 ? 241.865 262.659 240.700 1.00 19.94  ? 286 TYR A N   1 
ATOM   2064  C  CA  . TYR A 1 286 ? 242.150 263.481 241.863 1.00 18.92  ? 286 TYR A CA  1 
ATOM   2065  C  C   . TYR A 1 286 ? 242.925 262.674 242.899 1.00 19.28  ? 286 TYR A C   1 
ATOM   2066  O  O   . TYR A 1 286 ? 242.784 261.450 242.974 1.00 20.41  ? 286 TYR A O   1 
ATOM   2067  C  CB  . TYR A 1 286 ? 240.857 264.002 242.485 1.00 20.05  ? 286 TYR A CB  1 
ATOM   2068  C  CG  . TYR A 1 286 ? 240.141 265.056 241.667 1.00 19.16  ? 286 TYR A CG  1 
ATOM   2069  C  CD1 . TYR A 1 286 ? 239.794 264.824 240.344 1.00 21.54  ? 286 TYR A CD1 1 
ATOM   2070  C  CD2 . TYR A 1 286 ? 239.812 266.285 242.222 1.00 19.47  ? 286 TYR A CD2 1 
ATOM   2071  C  CE1 . TYR A 1 286 ? 239.139 265.781 239.598 1.00 24.04  ? 286 TYR A CE1 1 
ATOM   2072  C  CE2 . TYR A 1 286 ? 239.156 267.249 241.483 1.00 18.73  ? 286 TYR A CE2 1 
ATOM   2073  C  CZ  . TYR A 1 286 ? 238.822 266.992 240.171 1.00 26.62  ? 286 TYR A CZ  1 
ATOM   2074  O  OH  . TYR A 1 286 ? 238.170 267.947 239.427 1.00 33.44  ? 286 TYR A OH  1 
ATOM   2075  N  N   . PRO A 1 287 ? 243.755 263.329 243.707 1.00 20.73  ? 287 PRO A N   1 
ATOM   2076  C  CA  . PRO A 1 287 ? 244.540 262.590 244.702 1.00 20.66  ? 287 PRO A CA  1 
ATOM   2077  C  C   . PRO A 1 287 ? 243.643 261.864 245.694 1.00 18.94  ? 287 PRO A C   1 
ATOM   2078  O  O   . PRO A 1 287 ? 242.599 262.372 246.107 1.00 19.34  ? 287 PRO A O   1 
ATOM   2079  C  CB  . PRO A 1 287 ? 245.373 263.681 245.383 1.00 19.46  ? 287 PRO A CB  1 
ATOM   2080  C  CG  . PRO A 1 287 ? 244.669 264.958 245.090 1.00 19.92  ? 287 PRO A CG  1 
ATOM   2081  C  CD  . PRO A 1 287 ? 243.977 264.781 243.777 1.00 18.32  ? 287 PRO A CD  1 
ATOM   2082  N  N   . VAL A 1 288 ? 244.066 260.665 246.077 1.00 19.53  ? 288 VAL A N   1 
ATOM   2083  C  CA  . VAL A 1 288 ? 243.336 259.863 247.052 1.00 15.87  ? 288 VAL A CA  1 
ATOM   2084  C  C   . VAL A 1 288 ? 243.594 260.421 248.445 1.00 18.80  ? 288 VAL A C   1 
ATOM   2085  O  O   . VAL A 1 288 ? 244.743 260.683 248.820 1.00 23.47  ? 288 VAL A O   1 
ATOM   2086  C  CB  . VAL A 1 288 ? 243.746 258.384 246.954 1.00 15.07  ? 288 VAL A CB  1 
ATOM   2087  C  CG1 . VAL A 1 288 ? 245.202 258.207 247.345 1.00 14.25  ? 288 VAL A CG1 1 
ATOM   2088  C  CG2 . VAL A 1 288 ? 242.844 257.511 247.819 1.00 16.97  ? 288 VAL A CG2 1 
ATOM   2089  N  N   . VAL A 1 289 ? 242.524 260.606 249.214 1.00 18.88  ? 289 VAL A N   1 
ATOM   2090  C  CA  . VAL A 1 289 ? 242.632 261.117 250.575 1.00 19.84  ? 289 VAL A CA  1 
ATOM   2091  C  C   . VAL A 1 289 ? 242.009 260.109 251.528 1.00 21.76  ? 289 VAL A C   1 
ATOM   2092  O  O   . VAL A 1 289 ? 241.523 259.056 251.102 1.00 22.72  ? 289 VAL A O   1 
ATOM   2093  C  CB  . VAL A 1 289 ? 241.969 262.499 250.715 1.00 19.29  ? 289 VAL A CB  1 
ATOM   2094  C  CG1 . VAL A 1 289 ? 242.700 263.520 249.866 1.00 16.98  ? 289 VAL A CG1 1 
ATOM   2095  C  CG2 . VAL A 1 289 ? 240.505 262.428 250.326 1.00 15.72  ? 289 VAL A CG2 1 
ATOM   2096  N  N   . GLY A 1 290 ? 242.021 260.419 252.821 1.00 18.64  ? 290 GLY A N   1 
ATOM   2097  C  CA  . GLY A 1 290 ? 241.552 259.466 253.805 1.00 19.10  ? 290 GLY A CA  1 
ATOM   2098  C  C   . GLY A 1 290 ? 242.413 258.234 253.926 1.00 23.53  ? 290 GLY A C   1 
ATOM   2099  O  O   . GLY A 1 290 ? 241.949 257.212 254.437 1.00 29.05  ? 290 GLY A O   1 
ATOM   2100  N  N   . ILE A 1 291 ? 243.659 258.301 253.468 1.00 21.82  ? 291 ILE A N   1 
ATOM   2101  C  CA  . ILE A 1 291 ? 244.578 257.171 253.492 1.00 18.97  ? 291 ILE A CA  1 
ATOM   2102  C  C   . ILE A 1 291 ? 245.526 257.345 254.667 1.00 18.88  ? 291 ILE A C   1 
ATOM   2103  O  O   . ILE A 1 291 ? 246.104 258.422 254.859 1.00 24.44  ? 291 ILE A O   1 
ATOM   2104  C  CB  . ILE A 1 291 ? 245.353 257.051 252.169 1.00 21.66  ? 291 ILE A CB  1 
ATOM   2105  C  CG1 . ILE A 1 291 ? 244.390 256.782 251.012 1.00 19.67  ? 291 ILE A CG1 1 
ATOM   2106  C  CG2 . ILE A 1 291 ? 246.394 255.946 252.254 1.00 15.99  ? 291 ILE A CG2 1 
ATOM   2107  C  CD1 . ILE A 1 291 ? 243.595 255.508 251.165 1.00 18.89  ? 291 ILE A CD1 1 
ATOM   2108  N  N   . SER A 1 292 ? 245.676 256.292 255.458 1.00 18.59  ? 292 SER A N   1 
ATOM   2109  C  CA  . SER A 1 292 ? 246.546 256.297 256.620 1.00 17.57  ? 292 SER A CA  1 
ATOM   2110  C  C   . SER A 1 292 ? 247.974 255.930 256.224 1.00 18.29  ? 292 SER A C   1 
ATOM   2111  O  O   . SER A 1 292 ? 248.228 255.379 255.151 1.00 20.74  ? 292 SER A O   1 
ATOM   2112  C  CB  . SER A 1 292 ? 246.016 255.327 257.676 1.00 15.01  ? 292 SER A CB  1 
ATOM   2113  O  OG  . SER A 1 292 ? 247.050 254.852 258.511 1.00 23.07  ? 292 SER A OG  1 
ATOM   2114  N  N   . TRP A 1 293 ? 248.913 256.251 257.116 1.00 18.28  ? 293 TRP A N   1 
ATOM   2115  C  CA  . TRP A 1 293 ? 250.317 255.925 256.879 1.00 15.60  ? 293 TRP A CA  1 
ATOM   2116  C  C   . TRP A 1 293 ? 250.508 254.427 256.666 1.00 20.20  ? 293 TRP A C   1 
ATOM   2117  O  O   . TRP A 1 293 ? 251.234 254.004 255.756 1.00 25.86  ? 293 TRP A O   1 
ATOM   2118  C  CB  . TRP A 1 293 ? 251.153 256.425 258.058 1.00 15.03  ? 293 TRP A CB  1 
ATOM   2119  C  CG  . TRP A 1 293 ? 252.636 256.315 257.894 1.00 17.59  ? 293 TRP A CG  1 
ATOM   2120  C  CD1 . TRP A 1 293 ? 253.460 257.196 257.262 1.00 17.81  ? 293 TRP A CD1 1 
ATOM   2121  C  CD2 . TRP A 1 293 ? 253.477 255.275 258.406 1.00 19.15  ? 293 TRP A CD2 1 
ATOM   2122  N  NE1 . TRP A 1 293 ? 254.760 256.763 257.334 1.00 19.28  ? 293 TRP A NE1 1 
ATOM   2123  C  CE2 . TRP A 1 293 ? 254.798 255.586 258.033 1.00 20.42  ? 293 TRP A CE2 1 
ATOM   2124  C  CE3 . TRP A 1 293 ? 253.240 254.109 259.139 1.00 17.37  ? 293 TRP A CE3 1 
ATOM   2125  C  CZ2 . TRP A 1 293 ? 255.877 254.772 258.365 1.00 22.07  ? 293 TRP A CZ2 1 
ATOM   2126  C  CZ3 . TRP A 1 293 ? 254.311 253.303 259.466 1.00 19.48  ? 293 TRP A CZ3 1 
ATOM   2127  C  CH2 . TRP A 1 293 ? 255.613 253.638 259.082 1.00 21.03  ? 293 TRP A CH2 1 
ATOM   2128  N  N   . GLU A 1 294 ? 249.854 253.609 257.493 1.00 16.55  ? 294 GLU A N   1 
ATOM   2129  C  CA  . GLU A 1 294 ? 249.959 252.161 257.353 1.00 18.29  ? 294 GLU A CA  1 
ATOM   2130  C  C   . GLU A 1 294 ? 249.364 251.686 256.033 1.00 22.34  ? 294 GLU A C   1 
ATOM   2131  O  O   . GLU A 1 294 ? 249.914 250.792 255.377 1.00 29.94  ? 294 GLU A O   1 
ATOM   2132  C  CB  . GLU A 1 294 ? 249.268 251.483 258.533 1.00 20.55  ? 294 GLU A CB  1 
ATOM   2133  C  CG  . GLU A 1 294 ? 249.651 252.077 259.878 1.00 22.50  ? 294 GLU A CG  1 
ATOM   2134  C  CD  . GLU A 1 294 ? 248.811 251.538 261.012 1.00 32.39  ? 294 GLU A CD  1 
ATOM   2135  O  OE1 . GLU A 1 294 ? 247.844 250.799 260.735 1.00 40.78  ? 294 GLU A OE1 1 
ATOM   2136  O  OE2 . GLU A 1 294 ? 249.112 251.855 262.181 1.00 34.05  ? 294 GLU A OE2 1 
ATOM   2137  N  N   . GLN A 1 295 ? 248.232 252.266 255.630 1.00 20.21  ? 295 GLN A N   1 
ATOM   2138  C  CA  . GLN A 1 295 ? 247.638 251.906 254.348 1.00 21.23  ? 295 GLN A CA  1 
ATOM   2139  C  C   . GLN A 1 295 ? 248.547 252.300 253.191 1.00 18.42  ? 295 GLN A C   1 
ATOM   2140  O  O   . GLN A 1 295 ? 248.640 251.577 252.194 1.00 19.44  ? 295 GLN A O   1 
ATOM   2141  C  CB  . GLN A 1 295 ? 246.264 252.558 254.205 1.00 19.53  ? 295 GLN A CB  1 
ATOM   2142  C  CG  . GLN A 1 295 ? 245.300 252.197 255.316 1.00 19.25  ? 295 GLN A CG  1 
ATOM   2143  C  CD  . GLN A 1 295 ? 243.975 252.911 255.193 1.00 22.71  ? 295 GLN A CD  1 
ATOM   2144  O  OE1 . GLN A 1 295 ? 243.927 254.127 255.020 1.00 28.85  ? 295 GLN A OE1 1 
ATOM   2145  N  NE2 . GLN A 1 295 ? 242.887 252.159 255.285 1.00 21.98  ? 295 GLN A NE2 1 
ATOM   2146  N  N   . ALA A 1 296 ? 249.219 253.448 253.300 1.00 19.58  ? 296 ALA A N   1 
ATOM   2147  C  CA  . ALA A 1 296 ? 250.161 253.854 252.261 1.00 18.97  ? 296 ALA A CA  1 
ATOM   2148  C  C   . ALA A 1 296 ? 251.337 252.890 252.177 1.00 24.50  ? 296 ALA A C   1 
ATOM   2149  O  O   . ALA A 1 296 ? 251.797 252.550 251.080 1.00 28.70  ? 296 ALA A O   1 
ATOM   2150  C  CB  . ALA A 1 296 ? 250.648 255.278 252.521 1.00 14.98  ? 296 ALA A CB  1 
ATOM   2151  N  N   . GLN A 1 297 ? 251.841 252.440 253.328 1.00 21.78  ? 297 GLN A N   1 
ATOM   2152  C  CA  . GLN A 1 297 ? 252.912 251.448 253.320 1.00 22.34  ? 297 GLN A CA  1 
ATOM   2153  C  C   . GLN A 1 297 ? 252.453 250.144 252.678 1.00 22.22  ? 297 GLN A C   1 
ATOM   2154  O  O   . GLN A 1 297 ? 253.191 249.531 251.896 1.00 28.36  ? 297 GLN A O   1 
ATOM   2155  C  CB  . GLN A 1 297 ? 253.400 251.201 254.744 1.00 24.46  ? 297 GLN A CB  1 
ATOM   2156  C  CG  . GLN A 1 297 ? 254.269 252.311 255.294 1.00 28.42  ? 297 GLN A CG  1 
ATOM   2157  C  CD  . GLN A 1 297 ? 255.244 251.812 256.331 1.00 39.90  ? 297 GLN A CD  1 
ATOM   2158  O  OE1 . GLN A 1 297 ? 256.378 252.280 256.411 1.00 41.88  ? 297 GLN A OE1 1 
ATOM   2159  N  NE2 . GLN A 1 297 ? 254.808 250.850 257.135 1.00 40.42  ? 297 GLN A NE2 1 
ATOM   2160  N  N   . ALA A 1 298 ? 251.236 249.702 253.002 1.00 23.07  ? 298 ALA A N   1 
ATOM   2161  C  CA  . ALA A 1 298 ? 250.706 248.491 252.386 1.00 18.76  ? 298 ALA A CA  1 
ATOM   2162  C  C   . ALA A 1 298 ? 250.552 248.661 250.879 1.00 22.00  ? 298 ALA A C   1 
ATOM   2163  O  O   . ALA A 1 298 ? 250.829 247.734 250.109 1.00 25.17  ? 298 ALA A O   1 
ATOM   2164  C  CB  . ALA A 1 298 ? 249.371 248.116 253.027 1.00 17.85  ? 298 ALA A CB  1 
ATOM   2165  N  N   . PHE A 1 299 ? 250.108 249.840 250.439 1.00 23.23  ? 299 PHE A N   1 
ATOM   2166  C  CA  . PHE A 1 299 ? 249.985 250.099 249.009 1.00 20.16  ? 299 PHE A CA  1 
ATOM   2167  C  C   . PHE A 1 299 ? 251.345 250.053 248.326 1.00 24.70  ? 299 PHE A C   1 
ATOM   2168  O  O   . PHE A 1 299 ? 251.472 249.520 247.220 1.00 27.47  ? 299 PHE A O   1 
ATOM   2169  C  CB  . PHE A 1 299 ? 249.303 251.449 248.770 1.00 16.92  ? 299 PHE A CB  1 
ATOM   2170  C  CG  . PHE A 1 299 ? 249.295 251.886 247.327 1.00 19.49  ? 299 PHE A CG  1 
ATOM   2171  C  CD1 . PHE A 1 299 ? 250.355 252.602 246.796 1.00 19.26  ? 299 PHE A CD1 1 
ATOM   2172  C  CD2 . PHE A 1 299 ? 248.225 251.580 246.502 1.00 19.34  ? 299 PHE A CD2 1 
ATOM   2173  C  CE1 . PHE A 1 299 ? 250.349 253.002 245.476 1.00 19.32  ? 299 PHE A CE1 1 
ATOM   2174  C  CE2 . PHE A 1 299 ? 248.214 251.981 245.180 1.00 18.04  ? 299 PHE A CE2 1 
ATOM   2175  C  CZ  . PHE A 1 299 ? 249.278 252.691 244.667 1.00 17.76  ? 299 PHE A CZ  1 
ATOM   2176  N  N   . CYS A 1 300 ? 252.373 250.615 248.965 1.00 22.72  ? 300 CYS A N   1 
ATOM   2177  C  CA  . CYS A 1 300 ? 253.710 250.568 248.380 1.00 20.21  ? 300 CYS A CA  1 
ATOM   2178  C  C   . CYS A 1 300 ? 254.223 249.135 248.289 1.00 22.49  ? 300 CYS A C   1 
ATOM   2179  O  O   . CYS A 1 300 ? 254.847 248.751 247.291 1.00 27.87  ? 300 CYS A O   1 
ATOM   2180  C  CB  . CYS A 1 300 ? 254.669 251.439 249.191 1.00 17.92  ? 300 CYS A CB  1 
ATOM   2181  S  SG  . CYS A 1 300 ? 254.306 253.208 249.117 1.00 35.54  ? 300 CYS A SG  1 
ATOM   2182  N  N   . ALA A 1 301 ? 253.971 248.327 249.321 1.00 22.51  ? 301 ALA A N   1 
ATOM   2183  C  CA  . ALA A 1 301 ? 254.375 246.924 249.266 1.00 22.16  ? 301 ALA A CA  1 
ATOM   2184  C  C   . ALA A 1 301 ? 253.655 246.186 248.143 1.00 22.66  ? 301 ALA A C   1 
ATOM   2185  O  O   . ALA A 1 301 ? 254.268 245.398 247.409 1.00 28.36  ? 301 ALA A O   1 
ATOM   2186  C  CB  . ALA A 1 301 ? 254.113 246.247 250.609 1.00 18.05  ? 301 ALA A CB  1 
ATOM   2187  N  N   . TRP A 1 302 ? 252.351 246.426 247.993 1.00 23.87  ? 302 TRP A N   1 
ATOM   2188  C  CA  . TRP A 1 302 ? 251.610 245.787 246.913 1.00 22.42  ? 302 TRP A CA  1 
ATOM   2189  C  C   . TRP A 1 302 ? 252.130 246.236 245.556 1.00 24.23  ? 302 TRP A C   1 
ATOM   2190  O  O   . TRP A 1 302 ? 252.197 245.441 244.614 1.00 29.06  ? 302 TRP A O   1 
ATOM   2191  C  CB  . TRP A 1 302 ? 250.119 246.090 247.033 1.00 21.88  ? 302 TRP A CB  1 
ATOM   2192  C  CG  . TRP A 1 302 ? 249.374 245.825 245.763 1.00 20.19  ? 302 TRP A CG  1 
ATOM   2193  C  CD1 . TRP A 1 302 ? 248.901 244.625 245.329 1.00 18.90  ? 302 TRP A CD1 1 
ATOM   2194  C  CD2 . TRP A 1 302 ? 249.042 246.778 244.747 1.00 20.13  ? 302 TRP A CD2 1 
ATOM   2195  N  NE1 . TRP A 1 302 ? 248.280 244.772 244.115 1.00 22.25  ? 302 TRP A NE1 1 
ATOM   2196  C  CE2 . TRP A 1 302 ? 248.354 246.085 243.735 1.00 21.09  ? 302 TRP A CE2 1 
ATOM   2197  C  CE3 . TRP A 1 302 ? 249.251 248.152 244.601 1.00 22.77  ? 302 TRP A CE3 1 
ATOM   2198  C  CZ2 . TRP A 1 302 ? 247.878 246.717 242.591 1.00 26.40  ? 302 TRP A CZ2 1 
ATOM   2199  C  CZ3 . TRP A 1 302 ? 248.780 248.776 243.465 1.00 22.44  ? 302 TRP A CZ3 1 
ATOM   2200  C  CH2 . TRP A 1 302 ? 248.099 248.061 242.475 1.00 27.49  ? 302 TRP A CH2 1 
ATOM   2201  N  N   . ARG A 1 303 ? 252.481 247.517 245.431 1.00 27.25  ? 303 ARG A N   1 
ATOM   2202  C  CA  . ARG A 1 303 ? 253.040 248.019 244.181 1.00 24.65  ? 303 ARG A CA  1 
ATOM   2203  C  C   . ARG A 1 303 ? 254.359 247.334 243.855 1.00 27.86  ? 303 ARG A C   1 
ATOM   2204  O  O   . ARG A 1 303 ? 254.611 246.975 242.700 1.00 29.80  ? 303 ARG A O   1 
ATOM   2205  C  CB  . ARG A 1 303 ? 253.226 249.532 244.269 1.00 23.63  ? 303 ARG A CB  1 
ATOM   2206  C  CG  . ARG A 1 303 ? 253.226 250.248 242.935 1.00 23.88  ? 303 ARG A CG  1 
ATOM   2207  C  CD  . ARG A 1 303 ? 253.809 251.639 243.081 1.00 24.33  ? 303 ARG A CD  1 
ATOM   2208  N  NE  . ARG A 1 303 ? 253.968 252.310 241.798 1.00 24.68  ? 303 ARG A NE  1 
ATOM   2209  C  CZ  . ARG A 1 303 ? 254.114 253.620 241.653 1.00 26.77  ? 303 ARG A CZ  1 
ATOM   2210  N  NH1 . ARG A 1 303 ? 254.119 254.432 242.696 1.00 21.47  ? 303 ARG A NH1 1 
ATOM   2211  N  NH2 . ARG A 1 303 ? 254.256 254.126 240.433 1.00 30.37  ? 303 ARG A NH2 1 
ATOM   2212  N  N   . SER A 1 304 ? 255.219 247.154 244.859 1.00 27.41  ? 304 SER A N   1 
ATOM   2213  C  CA  . SER A 1 304 ? 256.484 246.462 244.628 1.00 28.52  ? 304 SER A CA  1 
ATOM   2214  C  C   . SER A 1 304 ? 256.247 245.023 244.184 1.00 37.34  ? 304 SER A C   1 
ATOM   2215  O  O   . SER A 1 304 ? 256.880 244.536 243.239 1.00 42.57  ? 304 SER A O   1 
ATOM   2216  C  CB  . SER A 1 304 ? 257.344 246.501 245.891 1.00 28.10  ? 304 SER A CB  1 
ATOM   2217  O  OG  . SER A 1 304 ? 257.346 247.793 246.465 1.00 30.42  ? 304 SER A OG  1 
ATOM   2218  N  N   . GLU A 1 305 ? 255.328 244.326 244.858 1.00 38.26  ? 305 GLU A N   1 
ATOM   2219  C  CA  . GLU A 1 305 ? 255.025 242.950 244.476 1.00 38.64  ? 305 GLU A CA  1 
ATOM   2220  C  C   . GLU A 1 305 ? 254.467 242.881 243.059 1.00 40.05  ? 305 GLU A C   1 
ATOM   2221  O  O   . GLU A 1 305 ? 254.848 242.007 242.270 1.00 44.82  ? 305 GLU A O   1 
ATOM   2222  C  CB  . GLU A 1 305 ? 254.042 242.341 245.474 1.00 39.15  ? 305 GLU A CB  1 
ATOM   2223  C  CG  . GLU A 1 305 ? 254.099 240.830 245.572 1.00 49.76  ? 305 GLU A CG  1 
ATOM   2224  C  CD  . GLU A 1 305 ? 252.767 240.228 245.968 1.00 61.93  ? 305 GLU A CD  1 
ATOM   2225  O  OE1 . GLU A 1 305 ? 251.763 240.971 245.995 1.00 57.22  ? 305 GLU A OE1 1 
ATOM   2226  O  OE2 . GLU A 1 305 ? 252.722 239.013 246.252 1.00 63.04  ? 305 GLU A OE2 1 
ATOM   2227  N  N   . PHE A 1 306 ? 253.563 243.802 242.720 1.00 41.35  ? 306 PHE A N   1 
ATOM   2228  C  CA  . PHE A 1 306 ? 252.975 243.841 241.387 1.00 41.85  ? 306 PHE A CA  1 
ATOM   2229  C  C   . PHE A 1 306 ? 254.035 244.095 240.325 1.00 47.50  ? 306 PHE A C   1 
ATOM   2230  O  O   . PHE A 1 306 ? 254.027 243.463 239.262 1.00 48.38  ? 306 PHE A O   1 
ATOM   2231  C  CB  . PHE A 1 306 ? 251.897 244.926 241.352 1.00 40.41  ? 306 PHE A CB  1 
ATOM   2232  C  CG  . PHE A 1 306 ? 250.894 244.763 240.252 1.00 50.34  ? 306 PHE A CG  1 
ATOM   2233  C  CD1 . PHE A 1 306 ? 249.982 243.723 240.278 1.00 53.21  ? 306 PHE A CD1 1 
ATOM   2234  C  CD2 . PHE A 1 306 ? 250.841 245.669 239.207 1.00 53.42  ? 306 PHE A CD2 1 
ATOM   2235  C  CE1 . PHE A 1 306 ? 249.050 243.579 239.274 1.00 53.19  ? 306 PHE A CE1 1 
ATOM   2236  C  CE2 . PHE A 1 306 ? 249.911 245.529 238.201 1.00 54.56  ? 306 PHE A CE2 1 
ATOM   2237  C  CZ  . PHE A 1 306 ? 249.014 244.483 238.234 1.00 54.91  ? 306 PHE A CZ  1 
ATOM   2238  N  N   . PHE A 1 307 ? 254.954 245.024 240.593 1.00 48.00  ? 307 PHE A N   1 
ATOM   2239  C  CA  . PHE A 1 307 ? 256.020 245.312 239.642 1.00 46.04  ? 307 PHE A CA  1 
ATOM   2240  C  C   . PHE A 1 307 ? 256.931 244.108 239.454 1.00 51.80  ? 307 PHE A C   1 
ATOM   2241  O  O   . PHE A 1 307 ? 257.317 243.782 238.326 1.00 57.43  ? 307 PHE A O   1 
ATOM   2242  C  CB  . PHE A 1 307 ? 256.820 246.526 240.111 1.00 43.84  ? 307 PHE A CB  1 
ATOM   2243  C  CG  . PHE A 1 307 ? 257.748 247.082 239.072 1.00 55.69  ? 307 PHE A CG  1 
ATOM   2244  C  CD1 . PHE A 1 307 ? 257.368 248.159 238.293 1.00 55.79  ? 307 PHE A CD1 1 
ATOM   2245  C  CD2 . PHE A 1 307 ? 259.005 246.535 238.882 1.00 58.68  ? 307 PHE A CD2 1 
ATOM   2246  C  CE1 . PHE A 1 307 ? 258.219 248.674 237.338 1.00 60.98  ? 307 PHE A CE1 1 
ATOM   2247  C  CE2 . PHE A 1 307 ? 259.861 247.047 237.929 1.00 60.22  ? 307 PHE A CE2 1 
ATOM   2248  C  CZ  . PHE A 1 307 ? 259.468 248.117 237.157 1.00 62.84  ? 307 PHE A CZ  1 
ATOM   2249  N  N   . ARG A 1 308 ? 257.290 243.436 240.550 1.00 53.35  ? 308 ARG A N   1 
ATOM   2250  C  CA  . ARG A 1 308 ? 258.149 242.262 240.435 1.00 50.42  ? 308 ARG A CA  1 
ATOM   2251  C  C   . ARG A 1 308 ? 257.459 241.151 239.654 1.00 55.54  ? 308 ARG A C   1 
ATOM   2252  O  O   . ARG A 1 308 ? 258.096 240.454 238.856 1.00 63.63  ? 308 ARG A O   1 
ATOM   2253  C  CB  . ARG A 1 308 ? 258.558 241.768 241.821 1.00 44.74  ? 308 ARG A CB  1 
ATOM   2254  C  CG  . ARG A 1 308 ? 259.660 242.586 242.467 1.00 45.79  ? 308 ARG A CG  1 
ATOM   2255  C  CD  . ARG A 1 308 ? 260.194 241.900 243.710 1.00 51.02  ? 308 ARG A CD  1 
ATOM   2256  N  NE  . ARG A 1 308 ? 259.617 242.447 244.931 1.00 58.38  ? 308 ARG A NE  1 
ATOM   2257  C  CZ  . ARG A 1 308 ? 258.610 241.895 245.594 1.00 58.47  ? 308 ARG A CZ  1 
ATOM   2258  N  NH1 . ARG A 1 308 ? 258.040 240.775 245.179 1.00 53.07  ? 308 ARG A NH1 1 
ATOM   2259  N  NH2 . ARG A 1 308 ? 258.165 242.479 246.703 1.00 52.54  ? 308 ARG A NH2 1 
ATOM   2260  N  N   . LYS A 1 309 ? 256.155 240.973 239.867 1.00 57.32  ? 309 LYS A N   1 
ATOM   2261  C  CA  . LYS A 1 309 ? 255.440 239.877 239.225 1.00 60.94  ? 309 LYS A CA  1 
ATOM   2262  C  C   . LYS A 1 309 ? 255.413 239.998 237.706 1.00 62.87  ? 309 LYS A C   1 
ATOM   2263  O  O   . LYS A 1 309 ? 255.130 239.007 237.025 1.00 65.21  ? 309 LYS A O   1 
ATOM   2264  C  CB  . LYS A 1 309 ? 254.012 239.804 239.766 1.00 57.55  ? 309 LYS A CB  1 
ATOM   2265  C  CG  . LYS A 1 309 ? 253.458 238.397 239.862 1.00 59.12  ? 309 LYS A CG  1 
ATOM   2266  C  CD  . LYS A 1 309 ? 251.968 238.414 240.144 1.00 65.65  ? 309 LYS A CD  1 
ATOM   2267  C  CE  . LYS A 1 309 ? 251.680 238.853 241.571 1.00 69.22  ? 309 LYS A CE  1 
ATOM   2268  N  NZ  . LYS A 1 309 ? 250.268 238.580 241.956 1.00 64.50  ? 309 LYS A NZ  1 
ATOM   2269  N  N   . GLY A 1 310 ? 255.699 241.176 237.157 1.00 69.82  ? 310 GLY A N   1 
ATOM   2270  C  CA  . GLY A 1 310 ? 255.573 241.376 235.726 1.00 75.60  ? 310 GLY A CA  1 
ATOM   2271  C  C   . GLY A 1 310 ? 256.840 241.794 235.005 1.00 82.77  ? 310 GLY A C   1 
ATOM   2272  O  O   . GLY A 1 310 ? 256.782 242.589 234.062 1.00 84.20  ? 310 GLY A O   1 
ATOM   2273  N  N   . ILE A 1 311 ? 257.988 241.272 235.429 1.00 82.55  ? 311 ILE A N   1 
ATOM   2274  C  CA  . ILE A 1 311 ? 259.265 241.571 234.791 1.00 88.98  ? 311 ILE A CA  1 
ATOM   2275  C  C   . ILE A 1 311 ? 260.151 240.336 234.860 1.00 92.52  ? 311 ILE A C   1 
ATOM   2276  O  O   . ILE A 1 311 ? 260.114 239.585 235.840 1.00 91.20  ? 311 ILE A O   1 
ATOM   2277  C  CB  . ILE A 1 311 ? 259.968 242.778 235.447 1.00 92.19  ? 311 ILE A CB  1 
ATOM   2278  C  CG1 . ILE A 1 311 ? 259.080 244.021 235.377 1.00 85.96  ? 311 ILE A CG1 1 
ATOM   2279  C  CG2 . ILE A 1 311 ? 261.306 243.041 234.775 1.00 92.69  ? 311 ILE A CG2 1 
ATOM   2280  C  CD1 . ILE A 1 311 ? 259.278 244.844 234.122 1.00 84.12  ? 311 ILE A CD1 1 
ATOM   2281  N  N   . ARG A 1 312 ? 260.950 240.128 233.816 1.00 95.54  ? 312 ARG A N   1 
ATOM   2282  C  CA  . ARG A 1 312 ? 261.912 239.035 233.763 1.00 100.41 ? 312 ARG A CA  1 
ATOM   2283  C  C   . ARG A 1 312 ? 263.286 239.580 234.130 1.00 104.06 ? 312 ARG A C   1 
ATOM   2284  O  O   . ARG A 1 312 ? 263.820 240.449 233.432 1.00 100.77 ? 312 ARG A O   1 
ATOM   2285  C  CB  . ARG A 1 312 ? 261.934 238.394 232.375 1.00 106.61 ? 312 ARG A CB  1 
ATOM   2286  C  CG  . ARG A 1 312 ? 260.595 237.818 231.939 1.00 108.34 ? 312 ARG A CG  1 
ATOM   2287  C  CD  . ARG A 1 312 ? 260.301 236.499 232.636 1.00 109.40 ? 312 ARG A CD  1 
ATOM   2288  N  NE  . ARG A 1 312 ? 261.270 235.466 232.288 1.00 115.51 ? 312 ARG A NE  1 
ATOM   2289  C  CZ  . ARG A 1 312 ? 262.279 235.093 233.063 1.00 117.05 ? 312 ARG A CZ  1 
ATOM   2290  N  NH1 . ARG A 1 312 ? 262.486 235.652 234.245 1.00 109.45 ? 312 ARG A NH1 1 
ATOM   2291  N  NH2 . ARG A 1 312 ? 263.100 234.135 232.643 1.00 116.91 ? 312 ARG A NH2 1 
ATOM   2292  N  N   . LEU A 1 313 ? 263.855 239.069 235.221 1.00 104.47 ? 313 LEU A N   1 
ATOM   2293  C  CA  . LEU A 1 313 ? 265.094 239.601 235.770 1.00 102.35 ? 313 LEU A CA  1 
ATOM   2294  C  C   . LEU A 1 313 ? 266.237 238.626 235.542 1.00 104.14 ? 313 LEU A C   1 
ATOM   2295  O  O   . LEU A 1 313 ? 266.127 237.452 235.928 1.00 103.79 ? 313 LEU A O   1 
ATOM   2296  C  CB  . LEU A 1 313 ? 264.938 239.889 237.261 1.00 99.45  ? 313 LEU A CB  1 
ATOM   2297  C  CG  . LEU A 1 313 ? 264.316 241.231 237.649 1.00 97.75  ? 313 LEU A CG  1 
ATOM   2298  C  CD1 . LEU A 1 313 ? 264.800 241.651 239.027 1.00 91.58  ? 313 LEU A CD1 1 
ATOM   2299  C  CD2 . LEU A 1 313 ? 264.634 242.296 236.613 1.00 92.43  ? 313 LEU A CD2 1 
ATOM   2300  N  N   . PRO A 1 314 ? 267.337 239.053 234.924 1.00 106.23 ? 314 PRO A N   1 
ATOM   2301  C  CA  . PRO A 1 314 ? 268.513 238.184 234.829 1.00 105.46 ? 314 PRO A CA  1 
ATOM   2302  C  C   . PRO A 1 314 ? 268.965 237.720 236.206 1.00 107.82 ? 314 PRO A C   1 
ATOM   2303  O  O   . PRO A 1 314 ? 268.652 238.326 237.233 1.00 107.02 ? 314 PRO A O   1 
ATOM   2304  C  CB  . PRO A 1 314 ? 269.566 239.080 234.168 1.00 102.94 ? 314 PRO A CB  1 
ATOM   2305  C  CG  . PRO A 1 314 ? 268.773 240.075 233.393 1.00 103.13 ? 314 PRO A CG  1 
ATOM   2306  C  CD  . PRO A 1 314 ? 267.513 240.312 234.180 1.00 103.75 ? 314 PRO A CD  1 
ATOM   2307  N  N   . GLU A 1 315 ? 269.715 236.621 236.213 1.00 108.86 ? 315 GLU A N   1 
ATOM   2308  C  CA  . GLU A 1 315 ? 270.144 236.015 237.466 1.00 110.10 ? 315 GLU A CA  1 
ATOM   2309  C  C   . GLU A 1 315 ? 270.933 237.012 238.307 1.00 108.26 ? 315 GLU A C   1 
ATOM   2310  O  O   . GLU A 1 315 ? 271.811 237.715 237.800 1.00 103.38 ? 315 GLU A O   1 
ATOM   2311  C  CB  . GLU A 1 315 ? 270.992 234.774 237.183 1.00 109.09 ? 315 GLU A CB  1 
ATOM   2312  C  CG  . GLU A 1 315 ? 271.311 233.938 238.412 1.00 112.93 ? 315 GLU A CG  1 
ATOM   2313  C  CD  . GLU A 1 315 ? 270.101 233.719 239.299 1.00 118.18 ? 315 GLU A CD  1 
ATOM   2314  O  OE1 . GLU A 1 315 ? 269.361 232.739 239.066 1.00 118.74 ? 315 GLU A OE1 1 
ATOM   2315  O  OE2 . GLU A 1 315 ? 269.890 234.522 240.231 1.00 114.96 ? 315 GLU A OE2 1 
ATOM   2316  N  N   . GLY A 1 316 ? 270.609 237.072 239.599 1.00 105.29 ? 316 GLY A N   1 
ATOM   2317  C  CA  . GLY A 1 316 ? 271.317 237.905 240.542 1.00 100.26 ? 316 GLY A CA  1 
ATOM   2318  C  C   . GLY A 1 316 ? 270.779 239.313 240.695 1.00 92.73  ? 316 GLY A C   1 
ATOM   2319  O  O   . GLY A 1 316 ? 271.134 239.992 241.665 1.00 87.14  ? 316 GLY A O   1 
ATOM   2320  N  N   . GLN A 1 317 ? 269.934 239.770 239.775 1.00 92.23  ? 317 GLN A N   1 
ATOM   2321  C  CA  . GLN A 1 317 ? 269.440 241.140 239.823 1.00 88.28  ? 317 GLN A CA  1 
ATOM   2322  C  C   . GLN A 1 317 ? 268.544 241.333 241.040 1.00 90.27  ? 317 GLN A C   1 
ATOM   2323  O  O   . GLN A 1 317 ? 267.545 240.625 241.205 1.00 94.36  ? 317 GLN A O   1 
ATOM   2324  C  CB  . GLN A 1 317 ? 268.684 241.476 238.540 1.00 88.47  ? 317 GLN A CB  1 
ATOM   2325  C  CG  . GLN A 1 317 ? 268.341 242.950 238.389 1.00 85.69  ? 317 GLN A CG  1 
ATOM   2326  C  CD  . GLN A 1 317 ? 268.443 243.433 236.954 1.00 86.71  ? 317 GLN A CD  1 
ATOM   2327  O  OE1 . GLN A 1 317 ? 268.649 242.643 236.034 1.00 89.19  ? 317 GLN A OE1 1 
ATOM   2328  N  NE2 . GLN A 1 317 ? 268.297 244.738 236.758 1.00 83.97  ? 317 GLN A NE2 1 
ATOM   2329  N  N   . ILE A 1 318 ? 268.901 242.291 241.891 1.00 87.57  ? 318 ILE A N   1 
ATOM   2330  C  CA  . ILE A 1 318 ? 268.113 242.654 243.063 1.00 87.60  ? 318 ILE A CA  1 
ATOM   2331  C  C   . ILE A 1 318 ? 267.622 244.079 242.865 1.00 82.26  ? 318 ILE A C   1 
ATOM   2332  O  O   . ILE A 1 318 ? 268.429 244.997 242.671 1.00 79.45  ? 318 ILE A O   1 
ATOM   2333  C  CB  . ILE A 1 318 ? 268.922 242.528 244.363 1.00 87.32  ? 318 ILE A CB  1 
ATOM   2334  C  CG1 . ILE A 1 318 ? 269.225 241.059 244.664 1.00 86.69  ? 318 ILE A CG1 1 
ATOM   2335  C  CG2 . ILE A 1 318 ? 268.171 243.165 245.522 1.00 73.67  ? 318 ILE A CG2 1 
ATOM   2336  C  CD1 . ILE A 1 318 ? 268.023 240.272 245.126 1.00 79.34  ? 318 ILE A CD1 1 
ATOM   2337  N  N   . MET A 1 319 ? 266.307 244.265 242.910 1.00 79.55  ? 319 MET A N   1 
ATOM   2338  C  CA  . MET A 1 319 ? 265.694 245.572 242.738 1.00 74.53  ? 319 MET A CA  1 
ATOM   2339  C  C   . MET A 1 319 ? 265.252 246.128 244.084 1.00 66.39  ? 319 MET A C   1 
ATOM   2340  O  O   . MET A 1 319 ? 265.036 245.392 245.050 1.00 61.94  ? 319 MET A O   1 
ATOM   2341  C  CB  . MET A 1 319 ? 264.490 245.503 241.793 1.00 73.30  ? 319 MET A CB  1 
ATOM   2342  C  CG  . MET A 1 319 ? 264.570 244.409 240.748 1.00 83.77  ? 319 MET A CG  1 
ATOM   2343  S  SD  . MET A 1 319 ? 263.032 244.263 239.821 1.00 100.09 ? 319 MET A SD  1 
ATOM   2344  C  CE  . MET A 1 319 ? 262.497 245.971 239.791 1.00 78.29  ? 319 MET A CE  1 
ATOM   2345  N  N   . ASP A 1 320 ? 265.120 247.449 244.132 1.00 58.93  ? 320 ASP A N   1 
ATOM   2346  C  CA  . ASP A 1 320 ? 264.599 248.129 245.306 1.00 50.52  ? 320 ASP A CA  1 
ATOM   2347  C  C   . ASP A 1 320 ? 263.083 248.245 245.208 1.00 47.30  ? 320 ASP A C   1 
ATOM   2348  O  O   . ASP A 1 320 ? 262.516 248.338 244.116 1.00 52.05  ? 320 ASP A O   1 
ATOM   2349  C  CB  . ASP A 1 320 ? 265.229 249.515 245.451 1.00 48.84  ? 320 ASP A CB  1 
ATOM   2350  C  CG  . ASP A 1 320 ? 265.112 250.065 246.858 1.00 52.87  ? 320 ASP A CG  1 
ATOM   2351  O  OD1 . ASP A 1 320 ? 265.568 249.386 247.802 1.00 48.01  ? 320 ASP A OD1 1 
ATOM   2352  O  OD2 . ASP A 1 320 ? 264.563 251.175 247.021 1.00 51.18  ? 320 ASP A OD2 1 
ATOM   2353  N  N   . ASP A 1 321 ? 262.430 248.234 246.363 1.00 42.04  ? 321 ASP A N   1 
ATOM   2354  C  CA  . ASP A 1 321 ? 260.979 248.283 246.429 1.00 38.01  ? 321 ASP A CA  1 
ATOM   2355  C  C   . ASP A 1 321 ? 260.482 249.725 246.414 1.00 33.18  ? 321 ASP A C   1 
ATOM   2356  O  O   . ASP A 1 321 ? 261.211 250.666 246.736 1.00 33.80  ? 321 ASP A O   1 
ATOM   2357  C  CB  . ASP A 1 321 ? 260.476 247.576 247.688 1.00 38.09  ? 321 ASP A CB  1 
ATOM   2358  C  CG  . ASP A 1 321 ? 260.471 246.067 247.549 1.00 48.10  ? 321 ASP A CG  1 
ATOM   2359  O  OD1 . ASP A 1 321 ? 260.479 245.573 246.403 1.00 45.24  ? 321 ASP A OD1 1 
ATOM   2360  O  OD2 . ASP A 1 321 ? 260.459 245.374 248.588 1.00 56.35  ? 321 ASP A OD2 1 
ATOM   2361  N  N   . PHE A 1 322 ? 259.220 249.888 246.024 1.00 30.01  ? 322 PHE A N   1 
ATOM   2362  C  CA  . PHE A 1 322 ? 258.554 251.171 246.182 1.00 23.83  ? 322 PHE A CA  1 
ATOM   2363  C  C   . PHE A 1 322 ? 258.370 251.481 247.662 1.00 26.64  ? 322 PHE A C   1 
ATOM   2364  O  O   . PHE A 1 322 ? 258.199 250.583 248.491 1.00 29.05  ? 322 PHE A O   1 
ATOM   2365  C  CB  . PHE A 1 322 ? 257.196 251.168 245.480 1.00 24.63  ? 322 PHE A CB  1 
ATOM   2366  C  CG  . PHE A 1 322 ? 257.280 251.101 243.983 1.00 25.79  ? 322 PHE A CG  1 
ATOM   2367  C  CD1 . PHE A 1 322 ? 257.345 252.258 243.228 1.00 25.36  ? 322 PHE A CD1 1 
ATOM   2368  C  CD2 . PHE A 1 322 ? 257.276 249.882 243.329 1.00 26.67  ? 322 PHE A CD2 1 
ATOM   2369  C  CE1 . PHE A 1 322 ? 257.415 252.198 241.852 1.00 26.70  ? 322 PHE A CE1 1 
ATOM   2370  C  CE2 . PHE A 1 322 ? 257.344 249.817 241.955 1.00 27.50  ? 322 PHE A CE2 1 
ATOM   2371  C  CZ  . PHE A 1 322 ? 257.414 250.977 241.215 1.00 27.75  ? 322 PHE A CZ  1 
ATOM   2372  N  N   . ARG A 1 323 ? 258.401 252.766 247.994 1.00 22.66  ? 323 ARG A N   1 
ATOM   2373  C  CA  . ARG A 1 323 ? 258.317 253.180 249.387 1.00 19.36  ? 323 ARG A CA  1 
ATOM   2374  C  C   . ARG A 1 323 ? 257.844 254.623 249.444 1.00 19.23  ? 323 ARG A C   1 
ATOM   2375  O  O   . ARG A 1 323 ? 257.834 255.336 248.439 1.00 22.96  ? 323 ARG A O   1 
ATOM   2376  C  CB  . ARG A 1 323 ? 259.667 253.032 250.093 1.00 18.45  ? 323 ARG A CB  1 
ATOM   2377  C  CG  . ARG A 1 323 ? 260.842 253.401 249.214 1.00 20.74  ? 323 ARG A CG  1 
ATOM   2378  C  CD  . ARG A 1 323 ? 262.114 253.585 250.013 1.00 20.82  ? 323 ARG A CD  1 
ATOM   2379  N  NE  . ARG A 1 323 ? 263.189 254.100 249.175 1.00 23.66  ? 323 ARG A NE  1 
ATOM   2380  C  CZ  . ARG A 1 323 ? 263.706 255.315 249.284 1.00 27.18  ? 323 ARG A CZ  1 
ATOM   2381  N  NH1 . ARG A 1 323 ? 263.277 256.169 250.198 1.00 29.67  ? 323 ARG A NH1 1 
ATOM   2382  N  NH2 . ARG A 1 323 ? 264.677 255.684 248.455 1.00 26.75  ? 323 ARG A NH2 1 
ATOM   2383  N  N   . LEU A 1 324 ? 257.436 255.040 250.638 1.00 20.64  ? 324 LEU A N   1 
ATOM   2384  C  CA  . LEU A 1 324 ? 257.244 256.454 250.893 1.00 20.28  ? 324 LEU A CA  1 
ATOM   2385  C  C   . LEU A 1 324 ? 258.601 257.151 250.961 1.00 23.29  ? 324 LEU A C   1 
ATOM   2386  O  O   . LEU A 1 324 ? 259.582 256.572 251.433 1.00 26.58  ? 324 LEU A O   1 
ATOM   2387  C  CB  . LEU A 1 324 ? 256.485 256.673 252.197 1.00 19.82  ? 324 LEU A CB  1 
ATOM   2388  C  CG  . LEU A 1 324 ? 255.016 256.259 252.237 1.00 19.71  ? 324 LEU A CG  1 
ATOM   2389  C  CD1 . LEU A 1 324 ? 254.491 256.308 253.662 1.00 19.80  ? 324 LEU A CD1 1 
ATOM   2390  C  CD2 . LEU A 1 324 ? 254.195 257.153 251.329 1.00 20.39  ? 324 LEU A CD2 1 
ATOM   2391  N  N   . PRO A 1 325 ? 258.686 258.390 250.489 1.00 24.73  ? 325 PRO A N   1 
ATOM   2392  C  CA  . PRO A 1 325 ? 259.954 259.117 250.569 1.00 24.01  ? 325 PRO A CA  1 
ATOM   2393  C  C   . PRO A 1 325 ? 260.284 259.490 252.004 1.00 24.66  ? 325 PRO A C   1 
ATOM   2394  O  O   . PRO A 1 325 ? 259.411 259.624 252.863 1.00 27.96  ? 325 PRO A O   1 
ATOM   2395  C  CB  . PRO A 1 325 ? 259.699 260.364 249.720 1.00 21.63  ? 325 PRO A CB  1 
ATOM   2396  C  CG  . PRO A 1 325 ? 258.239 260.590 249.853 1.00 20.97  ? 325 PRO A CG  1 
ATOM   2397  C  CD  . PRO A 1 325 ? 257.615 259.219 249.913 1.00 21.03  ? 325 PRO A CD  1 
ATOM   2398  N  N   . THR A 1 326 ? 261.576 259.657 252.258 1.00 24.69  ? 326 THR A N   1 
ATOM   2399  C  CA  . THR A 1 326 ? 261.983 260.297 253.494 1.00 26.79  ? 326 THR A CA  1 
ATOM   2400  C  C   . THR A 1 326 ? 261.698 261.792 253.404 1.00 23.52  ? 326 THR A C   1 
ATOM   2401  O  O   . THR A 1 326 ? 261.581 262.363 252.317 1.00 26.69  ? 326 THR A O   1 
ATOM   2402  C  CB  . THR A 1 326 ? 263.465 260.047 253.772 1.00 24.97  ? 326 THR A CB  1 
ATOM   2403  O  OG1 . THR A 1 326 ? 264.262 260.887 252.930 1.00 29.94  ? 326 THR A OG1 1 
ATOM   2404  C  CG2 . THR A 1 326 ? 263.816 258.597 253.495 1.00 23.83  ? 326 THR A CG2 1 
ATOM   2405  N  N   . GLU A 1 327 ? 261.571 262.434 254.565 1.00 21.20  ? 327 GLU A N   1 
ATOM   2406  C  CA  . GLU A 1 327 ? 261.283 263.863 254.557 1.00 24.59  ? 327 GLU A CA  1 
ATOM   2407  C  C   . GLU A 1 327 ? 262.423 264.646 253.918 1.00 28.25  ? 327 GLU A C   1 
ATOM   2408  O  O   . GLU A 1 327 ? 262.189 265.651 253.237 1.00 31.01  ? 327 GLU A O   1 
ATOM   2409  C  CB  . GLU A 1 327 ? 260.996 264.355 255.975 1.00 22.89  ? 327 GLU A CB  1 
ATOM   2410  C  CG  . GLU A 1 327 ? 262.217 264.577 256.839 1.00 26.03  ? 327 GLU A CG  1 
ATOM   2411  C  CD  . GLU A 1 327 ? 261.882 265.322 258.114 1.00 33.50  ? 327 GLU A CD  1 
ATOM   2412  O  OE1 . GLU A 1 327 ? 261.248 266.393 258.025 1.00 30.25  ? 327 GLU A OE1 1 
ATOM   2413  O  OE2 . GLU A 1 327 ? 262.243 264.834 259.205 1.00 44.27  ? 327 GLU A OE2 1 
ATOM   2414  N  N   . ALA A 1 328 ? 263.663 264.191 254.108 1.00 23.16  ? 328 ALA A N   1 
ATOM   2415  C  CA  . ALA A 1 328 ? 264.795 264.831 253.447 1.00 19.25  ? 328 ALA A CA  1 
ATOM   2416  C  C   . ALA A 1 328 ? 264.715 264.661 251.934 1.00 21.95  ? 328 ALA A C   1 
ATOM   2417  O  O   . ALA A 1 328 ? 264.923 265.619 251.180 1.00 24.68  ? 328 ALA A O   1 
ATOM   2418  C  CB  . ALA A 1 328 ? 266.107 264.265 253.986 1.00 22.91  ? 328 ALA A CB  1 
ATOM   2419  N  N   . GLU A 1 329 ? 264.412 263.446 251.471 1.00 22.86  ? 329 GLU A N   1 
ATOM   2420  C  CA  . GLU A 1 329 ? 264.238 263.227 250.039 1.00 21.53  ? 329 GLU A CA  1 
ATOM   2421  C  C   . GLU A 1 329 ? 263.111 264.088 249.489 1.00 25.39  ? 329 GLU A C   1 
ATOM   2422  O  O   . GLU A 1 329 ? 263.243 264.694 248.418 1.00 28.66  ? 329 GLU A O   1 
ATOM   2423  C  CB  . GLU A 1 329 ? 263.950 261.752 249.764 1.00 23.41  ? 329 GLU A CB  1 
ATOM   2424  C  CG  . GLU A 1 329 ? 265.174 260.886 249.565 1.00 25.25  ? 329 GLU A CG  1 
ATOM   2425  C  CD  . GLU A 1 329 ? 264.840 259.409 249.601 1.00 27.30  ? 329 GLU A CD  1 
ATOM   2426  O  OE1 . GLU A 1 329 ? 263.760 259.056 250.117 1.00 31.34  ? 329 GLU A OE1 1 
ATOM   2427  O  OE2 . GLU A 1 329 ? 265.654 258.600 249.113 1.00 30.22  ? 329 GLU A OE2 1 
ATOM   2428  N  N   . TRP A 1 330 ? 261.989 264.144 250.207 1.00 20.51  ? 330 TRP A N   1 
ATOM   2429  C  CA  . TRP A 1 330 ? 260.851 264.930 249.751 1.00 19.78  ? 330 TRP A CA  1 
ATOM   2430  C  C   . TRP A 1 330 ? 261.212 266.404 249.640 1.00 22.82  ? 330 TRP A C   1 
ATOM   2431  O  O   . TRP A 1 330 ? 260.901 267.056 248.639 1.00 25.38  ? 330 TRP A O   1 
ATOM   2432  C  CB  . TRP A 1 330 ? 259.665 264.736 250.695 1.00 20.52  ? 330 TRP A CB  1 
ATOM   2433  C  CG  . TRP A 1 330 ? 258.394 265.281 250.136 1.00 21.50  ? 330 TRP A CG  1 
ATOM   2434  C  CD1 . TRP A 1 330 ? 257.421 264.582 249.490 1.00 20.62  ? 330 TRP A CD1 1 
ATOM   2435  C  CD2 . TRP A 1 330 ? 257.962 266.647 250.154 1.00 20.60  ? 330 TRP A CD2 1 
ATOM   2436  N  NE1 . TRP A 1 330 ? 256.409 265.423 249.110 1.00 22.68  ? 330 TRP A NE1 1 
ATOM   2437  C  CE2 . TRP A 1 330 ? 256.716 266.697 249.506 1.00 19.55  ? 330 TRP A CE2 1 
ATOM   2438  C  CE3 . TRP A 1 330 ? 258.507 267.830 250.659 1.00 21.42  ? 330 TRP A CE3 1 
ATOM   2439  C  CZ2 . TRP A 1 330 ? 256.006 267.882 249.347 1.00 21.67  ? 330 TRP A CZ2 1 
ATOM   2440  C  CZ3 . TRP A 1 330 ? 257.802 269.004 250.501 1.00 20.21  ? 330 TRP A CZ3 1 
ATOM   2441  C  CH2 . TRP A 1 330 ? 256.565 269.022 249.850 1.00 22.73  ? 330 TRP A CH2 1 
ATOM   2442  N  N   . GLU A 1 331 ? 261.863 266.952 250.668 1.00 23.63  ? 331 GLU A N   1 
ATOM   2443  C  CA  . GLU A 1 331 ? 262.210 268.367 250.632 1.00 23.40  ? 331 GLU A CA  1 
ATOM   2444  C  C   . GLU A 1 331 ? 263.250 268.662 249.562 1.00 26.44  ? 331 GLU A C   1 
ATOM   2445  O  O   . GLU A 1 331 ? 263.218 269.735 248.950 1.00 32.36  ? 331 GLU A O   1 
ATOM   2446  C  CB  . GLU A 1 331 ? 262.704 268.829 252.002 1.00 24.20  ? 331 GLU A CB  1 
ATOM   2447  C  CG  . GLU A 1 331 ? 262.796 270.340 252.131 1.00 29.69  ? 331 GLU A CG  1 
ATOM   2448  C  CD  . GLU A 1 331 ? 263.154 270.795 253.530 1.00 33.16  ? 331 GLU A CD  1 
ATOM   2449  O  OE1 . GLU A 1 331 ? 262.948 270.019 254.484 1.00 38.89  ? 331 GLU A OE1 1 
ATOM   2450  O  OE2 . GLU A 1 331 ? 263.630 271.939 253.676 1.00 34.32  ? 331 GLU A OE2 1 
ATOM   2451  N  N   . TYR A 1 332 ? 264.180 267.735 249.323 1.00 23.39  ? 332 TYR A N   1 
ATOM   2452  C  CA  . TYR A 1 332 ? 265.139 267.924 248.242 1.00 19.56  ? 332 TYR A CA  1 
ATOM   2453  C  C   . TYR A 1 332 ? 264.446 267.940 246.885 1.00 22.96  ? 332 TYR A C   1 
ATOM   2454  O  O   . TYR A 1 332 ? 264.771 268.766 246.026 1.00 22.37  ? 332 TYR A O   1 
ATOM   2455  C  CB  . TYR A 1 332 ? 266.203 266.830 248.294 1.00 20.08  ? 332 TYR A CB  1 
ATOM   2456  C  CG  . TYR A 1 332 ? 267.130 266.815 247.102 1.00 21.74  ? 332 TYR A CG  1 
ATOM   2457  C  CD1 . TYR A 1 332 ? 268.239 267.646 247.050 1.00 19.81  ? 332 TYR A CD1 1 
ATOM   2458  C  CD2 . TYR A 1 332 ? 266.898 265.966 246.032 1.00 20.76  ? 332 TYR A CD2 1 
ATOM   2459  C  CE1 . TYR A 1 332 ? 269.087 267.634 245.964 1.00 19.20  ? 332 TYR A CE1 1 
ATOM   2460  C  CE2 . TYR A 1 332 ? 267.740 265.947 244.944 1.00 23.61  ? 332 TYR A CE2 1 
ATOM   2461  C  CZ  . TYR A 1 332 ? 268.833 266.781 244.914 1.00 20.02  ? 332 TYR A CZ  1 
ATOM   2462  O  OH  . TYR A 1 332 ? 269.673 266.762 243.827 1.00 26.65  ? 332 TYR A OH  1 
ATOM   2463  N  N   . ALA A 1 333 ? 263.486 267.037 246.674 1.00 24.28  ? 333 ALA A N   1 
ATOM   2464  C  CA  . ALA A 1 333 ? 262.819 266.967 245.378 1.00 22.93  ? 333 ALA A CA  1 
ATOM   2465  C  C   . ALA A 1 333 ? 261.880 268.150 245.164 1.00 24.85  ? 333 ALA A C   1 
ATOM   2466  O  O   . ALA A 1 333 ? 261.761 268.660 244.045 1.00 27.68  ? 333 ALA A O   1 
ATOM   2467  C  CB  . ALA A 1 333 ? 262.060 265.648 245.248 1.00 19.15  ? 333 ALA A CB  1 
ATOM   2468  N  N   . ALA A 1 334 ? 261.204 268.600 246.224 1.00 22.51  ? 334 ALA A N   1 
ATOM   2469  C  CA  . ALA A 1 334 ? 260.243 269.689 246.085 1.00 20.70  ? 334 ALA A CA  1 
ATOM   2470  C  C   . ALA A 1 334 ? 260.927 270.994 245.701 1.00 24.56  ? 334 ALA A C   1 
ATOM   2471  O  O   . ALA A 1 334 ? 260.405 271.756 244.880 1.00 25.77  ? 334 ALA A O   1 
ATOM   2472  C  CB  . ALA A 1 334 ? 259.452 269.861 247.381 1.00 21.48  ? 334 ALA A CB  1 
ATOM   2473  N  N   . ARG A 1 335 ? 262.090 271.270 246.281 1.00 22.41  ? 335 ARG A N   1 
ATOM   2474  C  CA  . ARG A 1 335 ? 262.812 272.507 246.028 1.00 22.72  ? 335 ARG A CA  1 
ATOM   2475  C  C   . ARG A 1 335 ? 263.784 272.394 244.861 1.00 26.31  ? 335 ARG A C   1 
ATOM   2476  O  O   . ARG A 1 335 ? 264.616 273.286 244.675 1.00 30.54  ? 335 ARG A O   1 
ATOM   2477  C  CB  . ARG A 1 335 ? 263.552 272.946 247.292 1.00 21.83  ? 335 ARG A CB  1 
ATOM   2478  C  CG  . ARG A 1 335 ? 262.633 273.511 248.360 1.00 24.58  ? 335 ARG A CG  1 
ATOM   2479  C  CD  . ARG A 1 335 ? 263.273 273.467 249.731 1.00 25.40  ? 335 ARG A CD  1 
ATOM   2480  N  NE  . ARG A 1 335 ? 264.332 274.458 249.869 1.00 32.35  ? 335 ARG A NE  1 
ATOM   2481  C  CZ  . ARG A 1 335 ? 265.080 274.606 250.952 1.00 31.33  ? 335 ARG A CZ  1 
ATOM   2482  N  NH1 . ARG A 1 335 ? 264.910 273.842 252.018 1.00 30.41  ? 335 ARG A NH1 1 
ATOM   2483  N  NH2 . ARG A 1 335 ? 266.021 275.544 250.967 1.00 31.54  ? 335 ARG A NH2 1 
ATOM   2484  N  N   . MET A 1 336 ? 263.687 271.328 244.067 1.00 25.21  ? 336 MET A N   1 
ATOM   2485  C  CA  . MET A 1 336 ? 264.556 271.128 242.908 1.00 26.56  ? 336 MET A CA  1 
ATOM   2486  C  C   . MET A 1 336 ? 266.028 271.126 243.313 1.00 27.88  ? 336 MET A C   1 
ATOM   2487  O  O   . MET A 1 336 ? 266.891 271.625 242.589 1.00 32.91  ? 336 MET A O   1 
ATOM   2488  C  CB  . MET A 1 336 ? 264.293 272.183 241.832 1.00 28.98  ? 336 MET A CB  1 
ATOM   2489  C  CG  . MET A 1 336 ? 262.837 272.316 241.429 1.00 30.19  ? 336 MET A CG  1 
ATOM   2490  S  SD  . MET A 1 336 ? 262.055 273.785 242.121 1.00 40.56  ? 336 MET A SD  1 
ATOM   2491  C  CE  . MET A 1 336 ? 262.458 274.997 240.870 1.00 30.38  ? 336 MET A CE  1 
ATOM   2492  N  N   . GLY A 1 337 ? 266.315 270.561 244.483 1.00 26.00  ? 337 GLY A N   1 
ATOM   2493  C  CA  . GLY A 1 337 ? 267.684 270.476 244.952 1.00 24.51  ? 337 GLY A CA  1 
ATOM   2494  C  C   . GLY A 1 337 ? 268.393 271.803 245.061 1.00 30.57  ? 337 GLY A C   1 
ATOM   2495  O  O   . GLY A 1 337 ? 269.623 271.846 244.991 1.00 36.68  ? 337 GLY A O   1 
ATOM   2496  N  N   . ASP A 1 338 ? 267.651 272.894 245.233 1.00 31.59  ? 338 ASP A N   1 
ATOM   2497  C  CA  . ASP A 1 338 ? 268.216 274.232 245.316 1.00 31.45  ? 338 ASP A CA  1 
ATOM   2498  C  C   . ASP A 1 338 ? 267.837 274.845 246.655 1.00 33.25  ? 338 ASP A C   1 
ATOM   2499  O  O   . ASP A 1 338 ? 266.655 274.880 247.014 1.00 34.02  ? 338 ASP A O   1 
ATOM   2500  C  CB  . ASP A 1 338 ? 267.717 275.107 244.162 1.00 33.66  ? 338 ASP A CB  1 
ATOM   2501  C  CG  . ASP A 1 338 ? 268.535 276.370 243.990 1.00 45.51  ? 338 ASP A CG  1 
ATOM   2502  O  OD1 . ASP A 1 338 ? 268.703 277.114 244.977 1.00 43.68  ? 338 ASP A OD1 1 
ATOM   2503  O  OD2 . ASP A 1 338 ? 269.009 276.621 242.863 1.00 54.77  ? 338 ASP A OD2 1 
ATOM   2504  N  N   . SER A 1 339 ? 268.838 275.329 247.390 1.00 33.46  ? 339 SER A N   1 
ATOM   2505  C  CA  . SER A 1 339 ? 268.602 275.902 248.708 1.00 31.83  ? 339 SER A CA  1 
ATOM   2506  C  C   . SER A 1 339 ? 268.046 277.318 248.651 1.00 38.90  ? 339 SER A C   1 
ATOM   2507  O  O   . SER A 1 339 ? 267.638 277.847 249.690 1.00 40.36  ? 339 SER A O   1 
ATOM   2508  C  CB  . SER A 1 339 ? 269.896 275.892 249.524 1.00 32.51  ? 339 SER A CB  1 
ATOM   2509  O  OG  . SER A 1 339 ? 270.672 274.744 249.231 1.00 33.90  ? 339 SER A OG  1 
ATOM   2510  N  N   . ASN A 1 340 ? 268.017 277.939 247.475 1.00 38.61  ? 340 ASN A N   1 
ATOM   2511  C  CA  . ASN A 1 340 ? 267.477 279.282 247.321 1.00 35.83  ? 340 ASN A CA  1 
ATOM   2512  C  C   . ASN A 1 340 ? 265.971 279.298 247.103 1.00 37.26  ? 340 ASN A C   1 
ATOM   2513  O  O   . ASN A 1 340 ? 265.382 280.382 247.050 1.00 43.22  ? 340 ASN A O   1 
ATOM   2514  C  CB  . ASN A 1 340 ? 268.163 279.997 246.153 1.00 39.12  ? 340 ASN A CB  1 
ATOM   2515  C  CG  . ASN A 1 340 ? 269.578 280.419 246.481 1.00 42.45  ? 340 ASN A CG  1 
ATOM   2516  O  OD1 . ASN A 1 340 ? 269.853 280.913 247.574 1.00 45.67  ? 340 ASN A OD1 1 
ATOM   2517  N  ND2 . ASN A 1 340 ? 270.487 280.228 245.533 1.00 46.64  ? 340 ASN A ND2 1 
ATOM   2518  N  N   . ASN A 1 341 ? 265.339 278.136 246.979 1.00 33.57  ? 341 ASN A N   1 
ATOM   2519  C  CA  . ASN A 1 341 ? 263.910 278.043 246.718 1.00 28.15  ? 341 ASN A CA  1 
ATOM   2520  C  C   . ASN A 1 341 ? 263.162 277.805 248.021 1.00 29.44  ? 341 ASN A C   1 
ATOM   2521  O  O   . ASN A 1 341 ? 263.526 276.917 248.798 1.00 36.65  ? 341 ASN A O   1 
ATOM   2522  C  CB  . ASN A 1 341 ? 263.609 276.918 245.728 1.00 30.62  ? 341 ASN A CB  1 
ATOM   2523  C  CG  . ASN A 1 341 ? 264.279 277.125 244.387 1.00 34.15  ? 341 ASN A CG  1 
ATOM   2524  O  OD1 . ASN A 1 341 ? 264.517 278.256 243.967 1.00 40.01  ? 341 ASN A OD1 1 
ATOM   2525  N  ND2 . ASN A 1 341 ? 264.587 276.029 243.707 1.00 32.05  ? 341 ASN A ND2 1 
ATOM   2526  N  N   . LYS A 1 342 ? 262.125 278.605 248.261 1.00 30.87  ? 342 LYS A N   1 
ATOM   2527  C  CA  . LYS A 1 342 ? 261.218 278.362 249.374 1.00 32.03  ? 342 LYS A CA  1 
ATOM   2528  C  C   . LYS A 1 342 ? 260.015 277.524 248.972 1.00 27.03  ? 342 LYS A C   1 
ATOM   2529  O  O   . LYS A 1 342 ? 259.395 276.897 249.836 1.00 32.28  ? 342 LYS A O   1 
ATOM   2530  C  CB  . LYS A 1 342 ? 260.734 279.687 249.969 1.00 35.83  ? 342 LYS A CB  1 
ATOM   2531  C  CG  . LYS A 1 342 ? 261.500 280.133 251.200 1.00 43.24  ? 342 LYS A CG  1 
ATOM   2532  C  CD  . LYS A 1 342 ? 261.681 281.642 251.220 1.00 59.83  ? 342 LYS A CD  1 
ATOM   2533  C  CE  . LYS A 1 342 ? 260.487 282.331 251.864 1.00 58.56  ? 342 LYS A CE  1 
ATOM   2534  N  NZ  . LYS A 1 342 ? 260.344 281.978 253.302 1.00 58.64  ? 342 LYS A NZ  1 
ATOM   2535  N  N   . TYR A 1 343 ? 259.679 277.501 247.689 1.00 27.01  ? 343 TYR A N   1 
ATOM   2536  C  CA  . TYR A 1 343 ? 258.544 276.750 247.176 1.00 27.21  ? 343 TYR A CA  1 
ATOM   2537  C  C   . TYR A 1 343 ? 259.004 275.881 246.013 1.00 27.86  ? 343 TYR A C   1 
ATOM   2538  O  O   . TYR A 1 343 ? 260.175 275.945 245.619 1.00 27.87  ? 343 TYR A O   1 
ATOM   2539  C  CB  . TYR A 1 343 ? 257.432 277.696 246.726 1.00 29.30  ? 343 TYR A CB  1 
ATOM   2540  C  CG  . TYR A 1 343 ? 256.925 278.626 247.802 1.00 29.38  ? 343 TYR A CG  1 
ATOM   2541  C  CD1 . TYR A 1 343 ? 256.039 278.182 248.772 1.00 31.06  ? 343 TYR A CD1 1 
ATOM   2542  C  CD2 . TYR A 1 343 ? 257.327 279.953 247.842 1.00 29.26  ? 343 TYR A CD2 1 
ATOM   2543  C  CE1 . TYR A 1 343 ? 255.570 279.031 249.751 1.00 32.07  ? 343 TYR A CE1 1 
ATOM   2544  C  CE2 . TYR A 1 343 ? 256.863 280.810 248.817 1.00 34.08  ? 343 TYR A CE2 1 
ATOM   2545  C  CZ  . TYR A 1 343 ? 255.985 280.344 249.769 1.00 36.63  ? 343 TYR A CZ  1 
ATOM   2546  O  OH  . TYR A 1 343 ? 255.522 281.198 250.743 1.00 39.76  ? 343 TYR A OH  1 
ATOM   2547  N  N   . PRO A 1 344 ? 258.129 275.054 245.442 1.00 28.62  ? 344 PRO A N   1 
ATOM   2548  C  CA  . PRO A 1 344 ? 258.514 274.304 244.240 1.00 27.69  ? 344 PRO A CA  1 
ATOM   2549  C  C   . PRO A 1 344 ? 258.476 275.162 242.985 1.00 27.59  ? 344 PRO A C   1 
ATOM   2550  O  O   . PRO A 1 344 ? 257.968 274.735 241.944 1.00 30.32  ? 344 PRO A O   1 
ATOM   2551  C  CB  . PRO A 1 344 ? 257.475 273.175 244.181 1.00 24.01  ? 344 PRO A CB  1 
ATOM   2552  C  CG  . PRO A 1 344 ? 256.857 273.134 245.541 1.00 23.00  ? 344 PRO A CG  1 
ATOM   2553  C  CD  . PRO A 1 344 ? 256.881 274.543 246.027 1.00 24.39  ? 344 PRO A CD  1 
ATOM   2554  N  N   . TRP A 1 345 ? 259.023 276.371 243.074 1.00 28.05  ? 345 TRP A N   1 
ATOM   2555  C  CA  . TRP A 1 345 ? 259.168 277.246 241.919 1.00 30.52  ? 345 TRP A CA  1 
ATOM   2556  C  C   . TRP A 1 345 ? 260.255 278.265 242.220 1.00 37.82  ? 345 TRP A C   1 
ATOM   2557  O  O   . TRP A 1 345 ? 260.631 278.477 243.375 1.00 37.97  ? 345 TRP A O   1 
ATOM   2558  C  CB  . TRP A 1 345 ? 257.849 277.937 241.548 1.00 33.21  ? 345 TRP A CB  1 
ATOM   2559  C  CG  . TRP A 1 345 ? 257.103 278.542 242.701 1.00 32.14  ? 345 TRP A CG  1 
ATOM   2560  C  CD1 . TRP A 1 345 ? 257.363 279.729 243.317 1.00 33.59  ? 345 TRP A CD1 1 
ATOM   2561  C  CD2 . TRP A 1 345 ? 255.960 277.990 243.361 1.00 30.60  ? 345 TRP A CD2 1 
ATOM   2562  N  NE1 . TRP A 1 345 ? 256.457 279.949 244.325 1.00 32.11  ? 345 TRP A NE1 1 
ATOM   2563  C  CE2 . TRP A 1 345 ? 255.584 278.894 244.372 1.00 32.78  ? 345 TRP A CE2 1 
ATOM   2564  C  CE3 . TRP A 1 345 ? 255.219 276.817 243.196 1.00 26.06  ? 345 TRP A CE3 1 
ATOM   2565  C  CZ2 . TRP A 1 345 ? 254.502 278.661 245.215 1.00 27.80  ? 345 TRP A CZ2 1 
ATOM   2566  C  CZ3 . TRP A 1 345 ? 254.147 276.588 244.032 1.00 27.32  ? 345 TRP A CZ3 1 
ATOM   2567  C  CH2 . TRP A 1 345 ? 253.798 277.505 245.029 1.00 27.40  ? 345 TRP A CH2 1 
ATOM   2568  N  N   . SER A 1 346 ? 260.753 278.897 241.156 1.00 42.23  ? 346 SER A N   1 
ATOM   2569  C  CA  . SER A 1 346 ? 261.914 279.770 241.288 1.00 45.88  ? 346 SER A CA  1 
ATOM   2570  C  C   . SER A 1 346 ? 261.582 281.044 242.055 1.00 48.16  ? 346 SER A C   1 
ATOM   2571  O  O   . SER A 1 346 ? 262.340 281.457 242.940 1.00 50.02  ? 346 SER A O   1 
ATOM   2572  C  CB  . SER A 1 346 ? 262.469 280.110 239.906 1.00 47.65  ? 346 SER A CB  1 
ATOM   2573  O  OG  . SER A 1 346 ? 261.632 281.037 239.239 1.00 57.15  ? 346 SER A OG  1 
ATOM   2574  N  N   . THR A 1 347 ? 260.461 281.681 241.734 1.00 49.19  ? 347 THR A N   1 
ATOM   2575  C  CA  . THR A 1 347 ? 260.152 282.974 242.322 1.00 52.50  ? 347 THR A CA  1 
ATOM   2576  C  C   . THR A 1 347 ? 259.751 282.830 243.788 1.00 55.56  ? 347 THR A C   1 
ATOM   2577  O  O   . THR A 1 347 ? 259.384 281.752 244.263 1.00 56.13  ? 347 THR A O   1 
ATOM   2578  C  CB  . THR A 1 347 ? 259.035 283.666 241.542 1.00 59.12  ? 347 THR A CB  1 
ATOM   2579  O  OG1 . THR A 1 347 ? 258.901 285.019 241.994 1.00 61.51  ? 347 THR A OG1 1 
ATOM   2580  C  CG2 . THR A 1 347 ? 257.715 282.936 241.737 1.00 53.54  ? 347 THR A CG2 1 
ATOM   2581  N  N   . GLU A 1 348 ? 259.838 283.947 244.510 1.00 55.55  ? 348 GLU A N   1 
ATOM   2582  C  CA  . GLU A 1 348 ? 259.407 284.006 245.899 1.00 56.44  ? 348 GLU A CA  1 
ATOM   2583  C  C   . GLU A 1 348 ? 257.924 284.315 246.046 1.00 57.71  ? 348 GLU A C   1 
ATOM   2584  O  O   . GLU A 1 348 ? 257.365 284.108 247.129 1.00 55.59  ? 348 GLU A O   1 
ATOM   2585  C  CB  . GLU A 1 348 ? 260.224 285.057 246.656 1.00 63.77  ? 348 GLU A CB  1 
ATOM   2586  C  CG  . GLU A 1 348 ? 259.713 285.367 248.053 1.00 63.50  ? 348 GLU A CG  1 
ATOM   2587  C  CD  . GLU A 1 348 ? 259.900 284.211 249.011 1.00 67.38  ? 348 GLU A CD  1 
ATOM   2588  O  OE1 . GLU A 1 348 ? 260.982 284.117 249.625 1.00 72.35  ? 348 GLU A OE1 1 
ATOM   2589  O  OE2 . GLU A 1 348 ? 258.964 283.397 249.151 1.00 64.68  ? 348 GLU A OE2 1 
ATOM   2590  N  N   . ASP A 1 349 ? 257.277 284.798 244.990 1.00 56.90  ? 349 ASP A N   1 
ATOM   2591  C  CA  . ASP A 1 349 ? 255.858 285.106 245.042 1.00 53.32  ? 349 ASP A CA  1 
ATOM   2592  C  C   . ASP A 1 349 ? 255.038 283.819 244.985 1.00 49.67  ? 349 ASP A C   1 
ATOM   2593  O  O   . ASP A 1 349 ? 255.567 282.714 244.837 1.00 49.87  ? 349 ASP A O   1 
ATOM   2594  C  CB  . ASP A 1 349 ? 255.473 286.046 243.902 1.00 59.24  ? 349 ASP A CB  1 
ATOM   2595  C  CG  . ASP A 1 349 ? 256.556 287.057 243.587 1.00 70.01  ? 349 ASP A CG  1 
ATOM   2596  O  OD1 . ASP A 1 349 ? 257.041 287.725 244.525 1.00 69.33  ? 349 ASP A OD1 1 
ATOM   2597  O  OD2 . ASP A 1 349 ? 256.920 287.186 242.399 1.00 73.20  ? 349 ASP A OD2 1 
ATOM   2598  N  N   . LEU A 1 350 ? 253.721 283.963 245.111 1.00 43.54  ? 350 LEU A N   1 
ATOM   2599  C  CA  . LEU A 1 350 ? 252.802 282.841 245.004 1.00 38.30  ? 350 LEU A CA  1 
ATOM   2600  C  C   . LEU A 1 350 ? 251.949 282.897 243.746 1.00 38.47  ? 350 LEU A C   1 
ATOM   2601  O  O   . LEU A 1 350 ? 251.117 282.009 243.538 1.00 35.87  ? 350 LEU A O   1 
ATOM   2602  C  CB  . LEU A 1 350 ? 251.902 282.776 246.244 1.00 33.01  ? 350 LEU A CB  1 
ATOM   2603  C  CG  . LEU A 1 350 ? 252.596 282.439 247.566 1.00 33.83  ? 350 LEU A CG  1 
ATOM   2604  C  CD1 . LEU A 1 350 ? 252.070 283.316 248.689 1.00 34.91  ? 350 LEU A CD1 1 
ATOM   2605  C  CD2 . LEU A 1 350 ? 252.428 280.968 247.912 1.00 28.43  ? 350 LEU A CD2 1 
ATOM   2606  N  N   . ARG A 1 351 ? 252.133 283.910 242.902 1.00 40.35  ? 351 ARG A N   1 
ATOM   2607  C  CA  . ARG A 1 351 ? 251.370 284.045 241.671 1.00 39.47  ? 351 ARG A CA  1 
ATOM   2608  C  C   . ARG A 1 351 ? 252.311 284.424 240.539 1.00 42.82  ? 351 ARG A C   1 
ATOM   2609  O  O   . ARG A 1 351 ? 253.390 284.978 240.759 1.00 51.41  ? 351 ARG A O   1 
ATOM   2610  C  CB  . ARG A 1 351 ? 250.261 285.097 241.801 1.00 41.43  ? 351 ARG A CB  1 
ATOM   2611  C  CG  . ARG A 1 351 ? 249.620 285.150 243.170 1.00 37.74  ? 351 ARG A CG  1 
ATOM   2612  C  CD  . ARG A 1 351 ? 248.963 286.492 243.413 1.00 37.54  ? 351 ARG A CD  1 
ATOM   2613  N  NE  . ARG A 1 351 ? 247.648 286.567 242.790 1.00 43.85  ? 351 ARG A NE  1 
ATOM   2614  C  CZ  . ARG A 1 351 ? 246.605 287.190 243.319 1.00 43.64  ? 351 ARG A CZ  1 
ATOM   2615  N  NH1 . ARG A 1 351 ? 246.689 287.806 244.486 1.00 45.26  ? 351 ARG A NH1 1 
ATOM   2616  N  NH2 . ARG A 1 351 ? 245.449 287.191 242.663 1.00 37.73  ? 351 ARG A NH2 1 
ATOM   2617  N  N   . THR A 1 352 ? 251.887 284.115 239.317 1.00 45.58  ? 352 THR A N   1 
ATOM   2618  C  CA  . THR A 1 352 ? 252.641 284.500 238.136 1.00 46.30  ? 352 THR A CA  1 
ATOM   2619  C  C   . THR A 1 352 ? 252.455 285.991 237.861 1.00 52.92  ? 352 THR A C   1 
ATOM   2620  O  O   . THR A 1 352 ? 251.729 286.700 238.563 1.00 56.26  ? 352 THR A O   1 
ATOM   2621  C  CB  . THR A 1 352 ? 252.206 283.673 236.930 1.00 47.97  ? 352 THR A CB  1 
ATOM   2622  O  OG1 . THR A 1 352 ? 250.882 284.057 236.542 1.00 53.42  ? 352 THR A OG1 1 
ATOM   2623  C  CG2 . THR A 1 352 ? 252.217 282.194 237.268 1.00 46.00  ? 352 THR A CG2 1 
ATOM   2624  N  N   . GLY A 1 353 ? 253.129 286.475 236.817 1.00 53.57  ? 353 GLY A N   1 
ATOM   2625  C  CA  . GLY A 1 353 ? 252.974 287.863 236.426 1.00 53.37  ? 353 GLY A CA  1 
ATOM   2626  C  C   . GLY A 1 353 ? 251.568 288.219 235.996 1.00 56.41  ? 353 GLY A C   1 
ATOM   2627  O  O   . GLY A 1 353 ? 251.191 289.394 236.045 1.00 59.34  ? 353 GLY A O   1 
ATOM   2628  N  N   . ARG A 1 354 ? 250.782 287.231 235.576 1.00 57.81  ? 354 ARG A N   1 
ATOM   2629  C  CA  . ARG A 1 354 ? 249.403 287.442 235.161 1.00 59.84  ? 354 ARG A CA  1 
ATOM   2630  C  C   . ARG A 1 354 ? 248.408 287.247 236.299 1.00 56.94  ? 354 ARG A C   1 
ATOM   2631  O  O   . ARG A 1 354 ? 247.197 287.259 236.055 1.00 54.64  ? 354 ARG A O   1 
ATOM   2632  C  CB  . ARG A 1 354 ? 249.060 286.513 233.994 1.00 60.72  ? 354 ARG A CB  1 
ATOM   2633  C  CG  . ARG A 1 354 ? 249.112 287.192 232.634 1.00 66.65  ? 354 ARG A CG  1 
ATOM   2634  C  CD  . ARG A 1 354 ? 248.382 286.383 231.574 1.00 74.27  ? 354 ARG A CD  1 
ATOM   2635  N  NE  . ARG A 1 354 ? 247.211 285.697 232.107 1.00 78.78  ? 354 ARG A NE  1 
ATOM   2636  C  CZ  . ARG A 1 354 ? 247.041 284.382 232.082 1.00 77.67  ? 354 ARG A CZ  1 
ATOM   2637  N  NH1 . ARG A 1 354 ? 247.951 283.577 231.558 1.00 74.85  ? 354 ARG A NH1 1 
ATOM   2638  N  NH2 . ARG A 1 354 ? 245.931 283.862 232.598 1.00 75.24  ? 354 ARG A NH2 1 
ATOM   2639  N  N   . GLY A 1 355 ? 248.887 287.068 237.527 1.00 53.13  ? 355 GLY A N   1 
ATOM   2640  C  CA  . GLY A 1 355 ? 248.021 286.948 238.681 1.00 49.27  ? 355 GLY A CA  1 
ATOM   2641  C  C   . GLY A 1 355 ? 247.522 285.555 238.990 1.00 49.83  ? 355 GLY A C   1 
ATOM   2642  O  O   . GLY A 1 355 ? 246.708 285.399 239.907 1.00 46.99  ? 355 GLY A O   1 
ATOM   2643  N  N   . CYS A 1 356 ? 247.979 284.540 238.264 1.00 49.59  ? 356 CYS A N   1 
ATOM   2644  C  CA  . CYS A 1 356 ? 247.530 283.177 238.509 1.00 39.04  ? 356 CYS A CA  1 
ATOM   2645  C  C   . CYS A 1 356 ? 248.348 282.537 239.622 1.00 37.96  ? 356 CYS A C   1 
ATOM   2646  O  O   . CYS A 1 356 ? 249.574 282.662 239.662 1.00 42.85  ? 356 CYS A O   1 
ATOM   2647  C  CB  . CYS A 1 356 ? 247.636 282.346 237.232 1.00 45.27  ? 356 CYS A CB  1 
ATOM   2648  S  SG  . CYS A 1 356 ? 246.715 283.019 235.832 1.00 60.81  ? 356 CYS A SG  1 
ATOM   2649  N  N   . PHE A 1 357 ? 247.661 281.852 240.530 1.00 36.41  ? 357 PHE A N   1 
ATOM   2650  C  CA  . PHE A 1 357 ? 248.339 281.190 241.635 1.00 32.44  ? 357 PHE A CA  1 
ATOM   2651  C  C   . PHE A 1 357 ? 249.093 279.958 241.144 1.00 30.81  ? 357 PHE A C   1 
ATOM   2652  O  O   . PHE A 1 357 ? 248.746 279.351 240.128 1.00 32.65  ? 357 PHE A O   1 
ATOM   2653  C  CB  . PHE A 1 357 ? 247.336 280.805 242.722 1.00 29.90  ? 357 PHE A CB  1 
ATOM   2654  C  CG  . PHE A 1 357 ? 246.956 281.945 243.624 1.00 29.99  ? 357 PHE A CG  1 
ATOM   2655  C  CD1 . PHE A 1 357 ? 247.762 282.299 244.691 1.00 25.93  ? 357 PHE A CD1 1 
ATOM   2656  C  CD2 . PHE A 1 357 ? 245.795 282.664 243.402 1.00 27.80  ? 357 PHE A CD2 1 
ATOM   2657  C  CE1 . PHE A 1 357 ? 247.418 283.345 245.518 1.00 27.70  ? 357 PHE A CE1 1 
ATOM   2658  C  CE2 . PHE A 1 357 ? 245.446 283.712 244.228 1.00 26.21  ? 357 PHE A CE2 1 
ATOM   2659  C  CZ  . PHE A 1 357 ? 246.258 284.053 245.287 1.00 30.51  ? 357 PHE A CZ  1 
ATOM   2660  N  N   . LEU A 1 358 ? 250.141 279.595 241.879 1.00 29.85  ? 358 LEU A N   1 
ATOM   2661  C  CA  . LEU A 1 358 ? 251.033 278.513 241.489 1.00 27.26  ? 358 LEU A CA  1 
ATOM   2662  C  C   . LEU A 1 358 ? 250.662 277.172 242.106 1.00 27.65  ? 358 LEU A C   1 
ATOM   2663  O  O   . LEU A 1 358 ? 251.289 276.161 241.775 1.00 33.32  ? 358 LEU A O   1 
ATOM   2664  C  CB  . LEU A 1 358 ? 252.476 278.870 241.855 1.00 26.39  ? 358 LEU A CB  1 
ATOM   2665  C  CG  . LEU A 1 358 ? 253.012 280.132 241.178 1.00 29.88  ? 358 LEU A CG  1 
ATOM   2666  C  CD1 . LEU A 1 358 ? 254.278 280.615 241.859 1.00 35.90  ? 358 LEU A CD1 1 
ATOM   2667  C  CD2 . LEU A 1 358 ? 253.250 279.888 239.699 1.00 27.17  ? 358 LEU A CD2 1 
ATOM   2668  N  N   . GLY A 1 359 ? 249.666 277.133 242.984 1.00 26.17  ? 359 GLY A N   1 
ATOM   2669  C  CA  . GLY A 1 359 ? 249.260 275.889 243.607 1.00 19.84  ? 359 GLY A CA  1 
ATOM   2670  C  C   . GLY A 1 359 ? 247.860 276.016 244.163 1.00 21.57  ? 359 GLY A C   1 
ATOM   2671  O  O   . GLY A 1 359 ? 247.244 277.082 244.118 1.00 26.73  ? 359 GLY A O   1 
ATOM   2672  N  N   . ASN A 1 360 ? 247.360 274.906 244.696 1.00 19.47  ? 360 ASN A N   1 
ATOM   2673  C  CA  . ASN A 1 360 ? 246.008 274.826 245.241 1.00 15.88  ? 360 ASN A CA  1 
ATOM   2674  C  C   . ASN A 1 360 ? 246.108 274.767 246.761 1.00 17.20  ? 360 ASN A C   1 
ATOM   2675  O  O   . ASN A 1 360 ? 246.348 273.703 247.337 1.00 17.79  ? 360 ASN A O   1 
ATOM   2676  C  CB  . ASN A 1 360 ? 245.268 273.616 244.683 1.00 16.58  ? 360 ASN A CB  1 
ATOM   2677  C  CG  . ASN A 1 360 ? 243.911 273.412 245.327 1.00 17.56  ? 360 ASN A CG  1 
ATOM   2678  O  OD1 . ASN A 1 360 ? 243.360 274.319 245.948 1.00 25.91  ? 360 ASN A OD1 1 
ATOM   2679  N  ND2 . ASN A 1 360 ? 243.366 272.212 245.184 1.00 20.23  ? 360 ASN A ND2 1 
ATOM   2680  N  N   . PHE A 1 361 ? 245.921 275.914 247.403 1.00 18.29  ? 361 PHE A N   1 
ATOM   2681  C  CA  . PHE A 1 361 ? 245.948 276.021 248.857 1.00 17.26  ? 361 PHE A CA  1 
ATOM   2682  C  C   . PHE A 1 361 ? 244.846 276.997 249.256 1.00 18.95  ? 361 PHE A C   1 
ATOM   2683  O  O   . PHE A 1 361 ? 243.957 277.321 248.462 1.00 26.26  ? 361 PHE A O   1 
ATOM   2684  C  CB  . PHE A 1 361 ? 247.342 276.440 249.352 1.00 17.36  ? 361 PHE A CB  1 
ATOM   2685  C  CG  . PHE A 1 361 ? 247.742 277.833 248.950 1.00 18.68  ? 361 PHE A CG  1 
ATOM   2686  C  CD1 . PHE A 1 361 ? 247.977 278.147 247.623 1.00 16.91  ? 361 PHE A CD1 1 
ATOM   2687  C  CD2 . PHE A 1 361 ? 247.887 278.827 249.902 1.00 17.67  ? 361 PHE A CD2 1 
ATOM   2688  C  CE1 . PHE A 1 361 ? 248.341 279.423 247.255 1.00 18.22  ? 361 PHE A CE1 1 
ATOM   2689  C  CE2 . PHE A 1 361 ? 248.250 280.104 249.539 1.00 16.12  ? 361 PHE A CE2 1 
ATOM   2690  C  CZ  . PHE A 1 361 ? 248.480 280.403 248.214 1.00 19.74  ? 361 PHE A CZ  1 
ATOM   2691  N  N   . LYS A 1 362 ? 244.884 277.465 250.498 1.00 20.93  ? 362 LYS A N   1 
ATOM   2692  C  CA  . LYS A 1 362 ? 243.914 278.448 250.965 1.00 19.89  ? 362 LYS A CA  1 
ATOM   2693  C  C   . LYS A 1 362 ? 244.540 279.838 250.941 1.00 22.54  ? 362 LYS A C   1 
ATOM   2694  O  O   . LYS A 1 362 ? 245.129 280.270 251.939 1.00 24.16  ? 362 LYS A O   1 
ATOM   2695  C  CB  . LYS A 1 362 ? 243.430 278.095 252.372 1.00 20.61  ? 362 LYS A CB  1 
ATOM   2696  C  CG  . LYS A 1 362 ? 242.299 278.963 252.880 1.00 23.76  ? 362 LYS A CG  1 
ATOM   2697  C  CD  . LYS A 1 362 ? 242.223 278.932 254.396 1.00 27.06  ? 362 LYS A CD  1 
ATOM   2698  C  CE  . LYS A 1 362 ? 240.857 279.360 254.889 1.00 25.63  ? 362 LYS A CE  1 
ATOM   2699  N  NZ  . LYS A 1 362 ? 240.644 278.982 256.310 1.00 30.39  ? 362 LYS A NZ  1 
ATOM   2700  N  N   . PRO A 1 363 ? 244.436 280.566 249.825 1.00 22.72  ? 363 PRO A N   1 
ATOM   2701  C  CA  . PRO A 1 363 ? 245.159 281.845 249.728 1.00 23.01  ? 363 PRO A CA  1 
ATOM   2702  C  C   . PRO A 1 363 ? 244.577 282.946 250.594 1.00 24.35  ? 363 PRO A C   1 
ATOM   2703  O  O   . PRO A 1 363 ? 245.334 283.725 251.186 1.00 30.52  ? 363 PRO A O   1 
ATOM   2704  C  CB  . PRO A 1 363 ? 245.059 282.189 248.234 1.00 21.03  ? 363 PRO A CB  1 
ATOM   2705  C  CG  . PRO A 1 363 ? 244.699 280.912 247.556 1.00 19.48  ? 363 PRO A CG  1 
ATOM   2706  C  CD  . PRO A 1 363 ? 243.855 280.165 248.535 1.00 19.80  ? 363 PRO A CD  1 
ATOM   2707  N  N   . GLY A 1 364 ? 243.250 283.049 250.676 1.00 23.61  ? 364 GLY A N   1 
ATOM   2708  C  CA  . GLY A 1 364 ? 242.596 284.108 251.409 1.00 22.59  ? 364 GLY A CA  1 
ATOM   2709  C  C   . GLY A 1 364 ? 241.964 283.612 252.700 1.00 25.98  ? 364 GLY A C   1 
ATOM   2710  O  O   . GLY A 1 364 ? 241.898 282.419 252.984 1.00 31.12  ? 364 GLY A O   1 
ATOM   2711  N  N   . GLU A 1 365 ? 241.495 284.573 253.490 1.00 28.74  ? 365 GLU A N   1 
ATOM   2712  C  CA  . GLU A 1 365 ? 240.821 284.266 254.744 1.00 28.17  ? 365 GLU A CA  1 
ATOM   2713  C  C   . GLU A 1 365 ? 239.402 283.798 254.450 1.00 29.87  ? 365 GLU A C   1 
ATOM   2714  O  O   . GLU A 1 365 ? 238.593 284.558 253.907 1.00 33.20  ? 365 GLU A O   1 
ATOM   2715  C  CB  . GLU A 1 365 ? 240.806 285.488 255.654 1.00 26.90  ? 365 GLU A CB  1 
ATOM   2716  C  CG  . GLU A 1 365 ? 240.028 285.288 256.936 1.00 32.92  ? 365 GLU A CG  1 
ATOM   2717  C  CD  . GLU A 1 365 ? 239.847 286.578 257.700 1.00 46.53  ? 365 GLU A CD  1 
ATOM   2718  O  OE1 . GLU A 1 365 ? 239.865 287.650 257.060 1.00 49.72  ? 365 GLU A OE1 1 
ATOM   2719  O  OE2 . GLU A 1 365 ? 239.687 286.524 258.936 1.00 48.37  ? 365 GLU A OE2 1 
ATOM   2720  N  N   . GLY A 1 366 ? 239.100 282.553 254.806 1.00 33.08  ? 366 GLY A N   1 
ATOM   2721  C  CA  . GLY A 1 366 ? 237.819 281.974 254.460 1.00 22.38  ? 366 GLY A CA  1 
ATOM   2722  C  C   . GLY A 1 366 ? 237.671 281.836 252.961 1.00 24.72  ? 366 GLY A C   1 
ATOM   2723  O  O   . GLY A 1 366 ? 236.574 281.590 252.454 1.00 29.95  ? 366 GLY A O   1 
ATOM   2724  N  N   . ASP A 1 367 ? 238.779 281.992 252.242 1.00 29.46  ? 367 ASP A N   1 
ATOM   2725  C  CA  . ASP A 1 367 ? 238.799 282.035 250.782 1.00 24.27  ? 367 ASP A CA  1 
ATOM   2726  C  C   . ASP A 1 367 ? 239.704 280.913 250.281 1.00 23.79  ? 367 ASP A C   1 
ATOM   2727  O  O   . ASP A 1 367 ? 240.913 281.097 250.123 1.00 29.35  ? 367 ASP A O   1 
ATOM   2728  C  CB  . ASP A 1 367 ? 239.272 283.404 250.294 1.00 24.72  ? 367 ASP A CB  1 
ATOM   2729  C  CG  . ASP A 1 367 ? 239.161 283.562 248.794 1.00 30.98  ? 367 ASP A CG  1 
ATOM   2730  O  OD1 . ASP A 1 367 ? 238.782 282.588 248.114 1.00 36.44  ? 367 ASP A OD1 1 
ATOM   2731  O  OD2 . ASP A 1 367 ? 239.463 284.665 248.293 1.00 36.68  ? 367 ASP A OD2 1 
ATOM   2732  N  N   . TYR A 1 368 ? 239.113 279.744 250.038 1.00 23.98  ? 368 TYR A N   1 
ATOM   2733  C  CA  . TYR A 1 368 ? 239.845 278.612 249.487 1.00 22.15  ? 368 TYR A CA  1 
ATOM   2734  C  C   . TYR A 1 368 ? 239.934 278.651 247.969 1.00 25.34  ? 368 TYR A C   1 
ATOM   2735  O  O   . TYR A 1 368 ? 240.890 278.116 247.397 1.00 32.02  ? 368 TYR A O   1 
ATOM   2736  C  CB  . TYR A 1 368 ? 239.185 277.293 249.899 1.00 22.05  ? 368 TYR A CB  1 
ATOM   2737  C  CG  . TYR A 1 368 ? 239.062 277.077 251.389 1.00 23.84  ? 368 TYR A CG  1 
ATOM   2738  C  CD1 . TYR A 1 368 ? 238.099 277.747 252.131 1.00 22.14  ? 368 TYR A CD1 1 
ATOM   2739  C  CD2 . TYR A 1 368 ? 239.901 276.192 252.050 1.00 21.93  ? 368 TYR A CD2 1 
ATOM   2740  C  CE1 . TYR A 1 368 ? 237.981 277.547 253.489 1.00 22.69  ? 368 TYR A CE1 1 
ATOM   2741  C  CE2 . TYR A 1 368 ? 239.791 275.986 253.409 1.00 23.26  ? 368 TYR A CE2 1 
ATOM   2742  C  CZ  . TYR A 1 368 ? 238.830 276.666 254.123 1.00 27.40  ? 368 TYR A CZ  1 
ATOM   2743  O  OH  . TYR A 1 368 ? 238.718 276.462 255.477 1.00 34.72  ? 368 TYR A OH  1 
ATOM   2744  N  N   . THR A 1 369 ? 238.961 279.270 247.309 1.00 24.36  ? 369 THR A N   1 
ATOM   2745  C  CA  . THR A 1 369 ? 238.792 279.177 245.866 1.00 23.42  ? 369 THR A CA  1 
ATOM   2746  C  C   . THR A 1 369 ? 239.535 280.264 245.101 1.00 24.30  ? 369 THR A C   1 
ATOM   2747  O  O   . THR A 1 369 ? 239.356 280.376 243.885 1.00 25.10  ? 369 THR A O   1 
ATOM   2748  C  CB  . THR A 1 369 ? 237.305 279.230 245.513 1.00 22.75  ? 369 THR A CB  1 
ATOM   2749  O  OG1 . THR A 1 369 ? 236.703 280.350 246.172 1.00 25.47  ? 369 THR A OG1 1 
ATOM   2750  C  CG2 . THR A 1 369 ? 236.608 277.961 245.964 1.00 20.43  ? 369 THR A CG2 1 
ATOM   2751  N  N   . ALA A 1 370 ? 240.350 281.075 245.779 1.00 28.75  ? 370 ALA A N   1 
ATOM   2752  C  CA  . ALA A 1 370 ? 241.067 282.137 245.081 1.00 25.12  ? 370 ALA A CA  1 
ATOM   2753  C  C   . ALA A 1 370 ? 241.914 281.589 243.939 1.00 25.20  ? 370 ALA A C   1 
ATOM   2754  O  O   . ALA A 1 370 ? 242.095 282.268 242.923 1.00 29.72  ? 370 ALA A O   1 
ATOM   2755  C  CB  . ALA A 1 370 ? 241.938 282.919 246.063 1.00 19.76  ? 370 ALA A CB  1 
ATOM   2756  N  N   . ASP A 1 371 ? 242.430 280.370 244.080 1.00 23.48  ? 371 ASP A N   1 
ATOM   2757  C  CA  . ASP A 1 371 ? 243.206 279.725 243.029 1.00 23.34  ? 371 ASP A CA  1 
ATOM   2758  C  C   . ASP A 1 371 ? 242.346 278.911 242.072 1.00 25.08  ? 371 ASP A C   1 
ATOM   2759  O  O   . ASP A 1 371 ? 242.890 278.255 241.179 1.00 30.06  ? 371 ASP A O   1 
ATOM   2760  C  CB  . ASP A 1 371 ? 244.287 278.825 243.639 1.00 23.66  ? 371 ASP A CB  1 
ATOM   2761  C  CG  . ASP A 1 371 ? 243.795 278.051 244.844 1.00 22.37  ? 371 ASP A CG  1 
ATOM   2762  O  OD1 . ASP A 1 371 ? 242.659 277.537 244.811 1.00 22.17  ? 371 ASP A OD1 1 
ATOM   2763  O  OD2 . ASP A 1 371 ? 244.554 277.948 245.828 1.00 27.33  ? 371 ASP A OD2 1 
ATOM   2764  N  N   . GLY A 1 372 ? 241.025 278.938 242.233 1.00 25.33  ? 372 GLY A N   1 
ATOM   2765  C  CA  . GLY A 1 372 ? 240.119 278.223 241.364 1.00 19.72  ? 372 GLY A CA  1 
ATOM   2766  C  C   . GLY A 1 372 ? 239.624 276.899 241.904 1.00 23.06  ? 372 GLY A C   1 
ATOM   2767  O  O   . GLY A 1 372 ? 238.751 276.286 241.280 1.00 29.42  ? 372 GLY A O   1 
ATOM   2768  N  N   . HIS A 1 373 ? 240.150 276.441 243.038 1.00 23.11  ? 373 HIS A N   1 
ATOM   2769  C  CA  . HIS A 1 373 ? 239.783 275.144 243.589 1.00 20.29  ? 373 HIS A CA  1 
ATOM   2770  C  C   . HIS A 1 373 ? 239.567 275.270 245.087 1.00 22.22  ? 373 HIS A C   1 
ATOM   2771  O  O   . HIS A 1 373 ? 240.387 275.868 245.788 1.00 30.03  ? 373 HIS A O   1 
ATOM   2772  C  CB  . HIS A 1 373 ? 240.861 274.095 243.298 1.00 18.33  ? 373 HIS A CB  1 
ATOM   2773  C  CG  . HIS A 1 373 ? 241.145 273.916 241.841 1.00 21.56  ? 373 HIS A CG  1 
ATOM   2774  N  ND1 . HIS A 1 373 ? 240.400 273.084 241.035 1.00 22.76  ? 373 HIS A ND1 1 
ATOM   2775  C  CD2 . HIS A 1 373 ? 242.087 274.470 241.041 1.00 18.58  ? 373 HIS A CD2 1 
ATOM   2776  C  CE1 . HIS A 1 373 ? 240.873 273.129 239.803 1.00 20.31  ? 373 HIS A CE1 1 
ATOM   2777  N  NE2 . HIS A 1 373 ? 241.897 273.962 239.780 1.00 24.37  ? 373 HIS A NE2 1 
ATOM   2778  N  N   . LEU A 1 374 ? 238.463 274.703 245.569 1.00 20.12  ? 374 LEU A N   1 
ATOM   2779  C  CA  . LEU A 1 374 ? 238.172 274.673 246.998 1.00 21.89  ? 374 LEU A CA  1 
ATOM   2780  C  C   . LEU A 1 374 ? 238.732 273.408 247.643 1.00 24.21  ? 374 LEU A C   1 
ATOM   2781  O  O   . LEU A 1 374 ? 239.573 273.481 248.543 1.00 26.18  ? 374 LEU A O   1 
ATOM   2782  C  CB  . LEU A 1 374 ? 236.659 274.782 247.219 1.00 26.36  ? 374 LEU A CB  1 
ATOM   2783  C  CG  . LEU A 1 374 ? 236.098 274.308 248.559 1.00 28.13  ? 374 LEU A CG  1 
ATOM   2784  C  CD1 . LEU A 1 374 ? 236.697 275.102 249.702 1.00 28.29  ? 374 LEU A CD1 1 
ATOM   2785  C  CD2 . LEU A 1 374 ? 234.585 274.426 248.564 1.00 23.82  ? 374 LEU A CD2 1 
ATOM   2786  N  N   . ILE A 1 375 ? 238.277 272.247 247.185 1.00 25.64  ? 375 ILE A N   1 
ATOM   2787  C  CA  . ILE A 1 375 ? 238.816 270.957 247.607 1.00 21.61  ? 375 ILE A CA  1 
ATOM   2788  C  C   . ILE A 1 375 ? 239.945 270.588 246.651 1.00 22.93  ? 375 ILE A C   1 
ATOM   2789  O  O   . ILE A 1 375 ? 240.261 271.375 245.749 1.00 25.01  ? 375 ILE A O   1 
ATOM   2790  C  CB  . ILE A 1 375 ? 237.721 269.879 247.657 1.00 23.88  ? 375 ILE A CB  1 
ATOM   2791  C  CG1 . ILE A 1 375 ? 237.060 269.713 246.288 1.00 24.53  ? 375 ILE A CG1 1 
ATOM   2792  C  CG2 . ILE A 1 375 ? 236.692 270.219 248.723 1.00 20.19  ? 375 ILE A CG2 1 
ATOM   2793  C  CD1 . ILE A 1 375 ? 236.712 268.286 245.958 1.00 22.84  ? 375 ILE A CD1 1 
ATOM   2794  N  N   . PRO A 1 376 ? 240.594 269.435 246.812 1.00 24.20  ? 376 PRO A N   1 
ATOM   2795  C  CA  . PRO A 1 376 ? 241.722 269.103 245.935 1.00 22.77  ? 376 PRO A CA  1 
ATOM   2796  C  C   . PRO A 1 376 ? 241.324 269.133 244.467 1.00 22.21  ? 376 PRO A C   1 
ATOM   2797  O  O   . PRO A 1 376 ? 240.218 268.738 244.093 1.00 29.64  ? 376 PRO A O   1 
ATOM   2798  C  CB  . PRO A 1 376 ? 242.111 267.690 246.379 1.00 17.98  ? 376 PRO A CB  1 
ATOM   2799  C  CG  . PRO A 1 376 ? 241.646 267.599 247.778 1.00 23.13  ? 376 PRO A CG  1 
ATOM   2800  C  CD  . PRO A 1 376 ? 240.393 268.417 247.857 1.00 20.32  ? 376 PRO A CD  1 
ATOM   2801  N  N   . SER A 1 377 ? 242.242 269.610 243.635 1.00 20.20  ? 377 SER A N   1 
ATOM   2802  C  CA  . SER A 1 377 ? 242.032 269.674 242.199 1.00 17.43  ? 377 SER A CA  1 
ATOM   2803  C  C   . SER A 1 377 ? 242.608 268.436 241.518 1.00 21.17  ? 377 SER A C   1 
ATOM   2804  O  O   . SER A 1 377 ? 243.303 267.621 242.127 1.00 26.60  ? 377 SER A O   1 
ATOM   2805  C  CB  . SER A 1 377 ? 242.667 270.937 241.621 1.00 16.76  ? 377 SER A CB  1 
ATOM   2806  O  OG  . SER A 1 377 ? 244.050 270.997 241.919 1.00 26.48  ? 377 SER A OG  1 
ATOM   2807  N  N   . ARG A 1 378 ? 242.305 268.301 240.232 1.00 22.51  ? 378 ARG A N   1 
ATOM   2808  C  CA  . ARG A 1 378 ? 242.863 267.215 239.442 1.00 21.68  ? 378 ARG A CA  1 
ATOM   2809  C  C   . ARG A 1 378 ? 244.372 267.380 239.311 1.00 27.14  ? 378 ARG A C   1 
ATOM   2810  O  O   . ARG A 1 378 ? 244.880 268.492 239.146 1.00 30.90  ? 378 ARG A O   1 
ATOM   2811  C  CB  . ARG A 1 378 ? 242.204 267.179 238.065 1.00 23.09  ? 378 ARG A CB  1 
ATOM   2812  C  CG  . ARG A 1 378 ? 242.881 266.273 237.058 1.00 31.38  ? 378 ARG A CG  1 
ATOM   2813  C  CD  . ARG A 1 378 ? 242.071 266.218 235.778 1.00 37.65  ? 378 ARG A CD  1 
ATOM   2814  N  NE  . ARG A 1 378 ? 241.009 267.216 235.782 1.00 50.27  ? 378 ARG A NE  1 
ATOM   2815  C  CZ  . ARG A 1 378 ? 239.731 266.951 235.545 1.00 52.89  ? 378 ARG A CZ  1 
ATOM   2816  N  NH1 . ARG A 1 378 ? 239.318 265.724 235.274 1.00 49.94  ? 378 ARG A NH1 1 
ATOM   2817  N  NH2 . ARG A 1 378 ? 238.845 267.942 235.589 1.00 43.90  ? 378 ARG A NH2 1 
ATOM   2818  N  N   . VAL A 1 379 ? 245.093 266.259 239.382 1.00 25.30  ? 379 VAL A N   1 
ATOM   2819  C  CA  . VAL A 1 379 ? 246.547 266.320 239.378 1.00 25.05  ? 379 VAL A CA  1 
ATOM   2820  C  C   . VAL A 1 379 ? 247.044 266.925 238.068 1.00 26.92  ? 379 VAL A C   1 
ATOM   2821  O  O   . VAL A 1 379 ? 246.444 266.744 237.000 1.00 29.01  ? 379 VAL A O   1 
ATOM   2822  C  CB  . VAL A 1 379 ? 247.161 264.929 239.609 1.00 25.28  ? 379 VAL A CB  1 
ATOM   2823  C  CG1 . VAL A 1 379 ? 246.657 264.338 240.915 1.00 21.08  ? 379 VAL A CG1 1 
ATOM   2824  C  CG2 . VAL A 1 379 ? 246.857 264.005 238.441 1.00 18.57  ? 379 VAL A CG2 1 
ATOM   2825  N  N   . SER A 1 380 ? 248.151 267.664 238.159 1.00 25.33  ? 380 SER A N   1 
ATOM   2826  C  CA  . SER A 1 380 ? 248.771 268.311 237.008 1.00 25.22  ? 380 SER A CA  1 
ATOM   2827  C  C   . SER A 1 380 ? 247.977 269.528 236.548 1.00 27.12  ? 380 SER A C   1 
ATOM   2828  O  O   . SER A 1 380 ? 248.048 269.913 235.377 1.00 32.78  ? 380 SER A O   1 
ATOM   2829  C  CB  . SER A 1 380 ? 248.929 267.321 235.853 1.00 23.31  ? 380 SER A CB  1 
ATOM   2830  O  OG  . SER A 1 380 ? 249.961 266.389 236.117 1.00 29.88  ? 380 SER A OG  1 
ATOM   2831  N  N   . SER A 1 381 ? 247.216 270.140 237.456 1.00 25.47  ? 381 SER A N   1 
ATOM   2832  C  CA  . SER A 1 381 ? 246.459 271.340 237.125 1.00 22.78  ? 381 SER A CA  1 
ATOM   2833  C  C   . SER A 1 381 ? 247.311 272.603 237.129 1.00 24.25  ? 381 SER A C   1 
ATOM   2834  O  O   . SER A 1 381 ? 246.858 273.636 236.626 1.00 28.71  ? 381 SER A O   1 
ATOM   2835  C  CB  . SER A 1 381 ? 245.290 271.512 238.095 1.00 24.95  ? 381 SER A CB  1 
ATOM   2836  O  OG  . SER A 1 381 ? 244.234 270.623 237.783 1.00 29.34  ? 381 SER A OG  1 
ATOM   2837  N  N   . PHE A 1 382 ? 248.517 272.550 237.680 1.00 28.86  ? 382 PHE A N   1 
ATOM   2838  C  CA  . PHE A 1 382 ? 249.449 273.668 237.679 1.00 22.39  ? 382 PHE A CA  1 
ATOM   2839  C  C   . PHE A 1 382 ? 250.754 273.243 237.013 1.00 24.80  ? 382 PHE A C   1 
ATOM   2840  O  O   . PHE A 1 382 ? 250.895 272.120 236.526 1.00 30.28  ? 382 PHE A O   1 
ATOM   2841  C  CB  . PHE A 1 382 ? 249.691 274.177 239.103 1.00 22.58  ? 382 PHE A CB  1 
ATOM   2842  C  CG  . PHE A 1 382 ? 248.441 274.603 239.812 1.00 24.30  ? 382 PHE A CG  1 
ATOM   2843  C  CD1 . PHE A 1 382 ? 247.631 273.674 240.442 1.00 22.36  ? 382 PHE A CD1 1 
ATOM   2844  C  CD2 . PHE A 1 382 ? 248.074 275.935 239.846 1.00 24.56  ? 382 PHE A CD2 1 
ATOM   2845  C  CE1 . PHE A 1 382 ? 246.481 274.067 241.087 1.00 21.03  ? 382 PHE A CE1 1 
ATOM   2846  C  CE2 . PHE A 1 382 ? 246.927 276.334 240.495 1.00 21.85  ? 382 PHE A CE2 1 
ATOM   2847  C  CZ  . PHE A 1 382 ? 246.128 275.399 241.115 1.00 24.33  ? 382 PHE A CZ  1 
ATOM   2848  N  N   . SER A 1 383 ? 251.712 274.164 236.986 1.00 28.56  ? 383 SER A N   1 
ATOM   2849  C  CA  . SER A 1 383 ? 252.990 273.880 236.359 1.00 25.22  ? 383 SER A CA  1 
ATOM   2850  C  C   . SER A 1 383 ? 253.814 272.934 237.231 1.00 28.17  ? 383 SER A C   1 
ATOM   2851  O  O   . SER A 1 383 ? 253.651 272.901 238.453 1.00 30.27  ? 383 SER A O   1 
ATOM   2852  C  CB  . SER A 1 383 ? 253.763 275.172 236.118 1.00 26.11  ? 383 SER A CB  1 
ATOM   2853  O  OG  . SER A 1 383 ? 253.295 275.833 234.957 1.00 35.17  ? 383 SER A OG  1 
ATOM   2854  N  N   . PRO A 1 384 ? 254.703 272.150 236.626 1.00 26.84  ? 384 PRO A N   1 
ATOM   2855  C  CA  . PRO A 1 384 ? 255.532 271.235 237.418 1.00 23.27  ? 384 PRO A CA  1 
ATOM   2856  C  C   . PRO A 1 384 ? 256.816 271.875 237.921 1.00 27.97  ? 384 PRO A C   1 
ATOM   2857  O  O   . PRO A 1 384 ? 257.092 273.049 237.654 1.00 30.38  ? 384 PRO A O   1 
ATOM   2858  C  CB  . PRO A 1 384 ? 255.829 270.101 236.432 1.00 21.47  ? 384 PRO A CB  1 
ATOM   2859  C  CG  . PRO A 1 384 ? 255.848 270.780 235.109 1.00 24.57  ? 384 PRO A CG  1 
ATOM   2860  C  CD  . PRO A 1 384 ? 254.843 271.908 235.180 1.00 26.36  ? 384 PRO A CD  1 
ATOM   2861  N  N   . ASN A 1 385 ? 257.599 271.098 238.662 1.00 34.64  ? 385 ASN A N   1 
ATOM   2862  C  CA  . ASN A 1 385 ? 258.923 271.505 239.100 1.00 28.19  ? 385 ASN A CA  1 
ATOM   2863  C  C   . ASN A 1 385 ? 259.868 271.609 237.906 1.00 32.30  ? 385 ASN A C   1 
ATOM   2864  O  O   . ASN A 1 385 ? 259.522 271.282 236.767 1.00 32.45  ? 385 ASN A O   1 
ATOM   2865  C  CB  . ASN A 1 385 ? 259.476 270.498 240.104 1.00 27.58  ? 385 ASN A CB  1 
ATOM   2866  C  CG  . ASN A 1 385 ? 259.397 270.986 241.522 1.00 28.32  ? 385 ASN A CG  1 
ATOM   2867  O  OD1 . ASN A 1 385 ? 259.337 272.188 241.773 1.00 39.00  ? 385 ASN A OD1 1 
ATOM   2868  N  ND2 . ASN A 1 385 ? 259.400 270.055 242.466 1.00 25.60  ? 385 ASN A ND2 1 
ATOM   2869  N  N   . ASP A 1 386 ? 261.092 272.062 238.180 1.00 32.67  ? 386 ASP A N   1 
ATOM   2870  C  CA  . ASP A 1 386 ? 262.172 271.860 237.222 1.00 33.60  ? 386 ASP A CA  1 
ATOM   2871  C  C   . ASP A 1 386 ? 262.496 270.379 237.090 1.00 35.17  ? 386 ASP A C   1 
ATOM   2872  O  O   . ASP A 1 386 ? 262.846 269.905 236.003 1.00 39.94  ? 386 ASP A O   1 
ATOM   2873  C  CB  . ASP A 1 386 ? 263.409 272.651 237.645 1.00 37.40  ? 386 ASP A CB  1 
ATOM   2874  C  CG  . ASP A 1 386 ? 263.285 274.130 237.347 1.00 47.69  ? 386 ASP A CG  1 
ATOM   2875  O  OD1 . ASP A 1 386 ? 262.332 274.516 236.639 1.00 52.00  ? 386 ASP A OD1 1 
ATOM   2876  O  OD2 . ASP A 1 386 ? 264.138 274.907 237.822 1.00 57.06  ? 386 ASP A OD2 1 
ATOM   2877  N  N   . PHE A 1 387 ? 262.385 269.633 238.192 1.00 27.74  ? 387 PHE A N   1 
ATOM   2878  C  CA  . PHE A 1 387 ? 262.528 268.185 238.148 1.00 24.41  ? 387 PHE A CA  1 
ATOM   2879  C  C   . PHE A 1 387 ? 261.374 267.518 237.412 1.00 28.43  ? 387 PHE A C   1 
ATOM   2880  O  O   . PHE A 1 387 ? 261.519 266.377 236.962 1.00 36.64  ? 387 PHE A O   1 
ATOM   2881  C  CB  . PHE A 1 387 ? 262.623 267.624 239.568 1.00 26.66  ? 387 PHE A CB  1 
ATOM   2882  C  CG  . PHE A 1 387 ? 263.948 267.867 240.232 1.00 26.71  ? 387 PHE A CG  1 
ATOM   2883  C  CD1 . PHE A 1 387 ? 265.001 268.421 239.527 1.00 25.50  ? 387 PHE A CD1 1 
ATOM   2884  C  CD2 . PHE A 1 387 ? 264.137 267.548 241.565 1.00 22.01  ? 387 PHE A CD2 1 
ATOM   2885  C  CE1 . PHE A 1 387 ? 266.217 268.647 240.137 1.00 25.02  ? 387 PHE A CE1 1 
ATOM   2886  C  CE2 . PHE A 1 387 ? 265.351 267.769 242.179 1.00 23.72  ? 387 PHE A CE2 1 
ATOM   2887  C  CZ  . PHE A 1 387 ? 266.392 268.320 241.465 1.00 23.75  ? 387 PHE A CZ  1 
ATOM   2888  N  N   . GLY A 1 388 ? 260.242 268.197 237.278 1.00 29.30  ? 388 GLY A N   1 
ATOM   2889  C  CA  . GLY A 1 388 ? 259.075 267.637 236.640 1.00 23.92  ? 388 GLY A CA  1 
ATOM   2890  C  C   . GLY A 1 388 ? 258.031 267.066 237.573 1.00 26.67  ? 388 GLY A C   1 
ATOM   2891  O  O   . GLY A 1 388 ? 257.344 266.113 237.190 1.00 25.44  ? 388 GLY A O   1 
ATOM   2892  N  N   . LEU A 1 389 ? 257.882 267.617 238.774 1.00 26.06  ? 389 LEU A N   1 
ATOM   2893  C  CA  . LEU A 1 389 ? 256.945 267.110 239.765 1.00 22.59  ? 389 LEU A CA  1 
ATOM   2894  C  C   . LEU A 1 389 ? 255.772 268.070 239.912 1.00 25.40  ? 389 LEU A C   1 
ATOM   2895  O  O   . LEU A 1 389 ? 255.943 269.290 239.844 1.00 24.27  ? 389 LEU A O   1 
ATOM   2896  C  CB  . LEU A 1 389 ? 257.632 266.911 241.117 1.00 19.76  ? 389 LEU A CB  1 
ATOM   2897  C  CG  . LEU A 1 389 ? 258.817 265.945 241.119 1.00 21.07  ? 389 LEU A CG  1 
ATOM   2898  C  CD1 . LEU A 1 389 ? 259.787 266.277 242.237 1.00 18.39  ? 389 LEU A CD1 1 
ATOM   2899  C  CD2 . LEU A 1 389 ? 258.336 264.509 241.226 1.00 20.07  ? 389 LEU A CD2 1 
ATOM   2900  N  N   . TYR A 1 390 ? 254.584 267.512 240.119 1.00 28.30  ? 390 TYR A N   1 
ATOM   2901  C  CA  . TYR A 1 390 ? 253.352 268.280 240.207 1.00 20.14  ? 390 TYR A CA  1 
ATOM   2902  C  C   . TYR A 1 390 ? 252.822 268.281 241.633 1.00 20.96  ? 390 TYR A C   1 
ATOM   2903  O  O   . TYR A 1 390 ? 252.947 267.287 242.354 1.00 26.40  ? 390 TYR A O   1 
ATOM   2904  C  CB  . TYR A 1 390 ? 252.286 267.711 239.270 1.00 22.12  ? 390 TYR A CB  1 
ATOM   2905  C  CG  . TYR A 1 390 ? 252.543 267.964 237.805 1.00 21.97  ? 390 TYR A CG  1 
ATOM   2906  C  CD1 . TYR A 1 390 ? 252.112 269.135 237.199 1.00 21.95  ? 390 TYR A CD1 1 
ATOM   2907  C  CD2 . TYR A 1 390 ? 253.213 267.032 237.027 1.00 21.47  ? 390 TYR A CD2 1 
ATOM   2908  C  CE1 . TYR A 1 390 ? 252.337 269.369 235.862 1.00 23.83  ? 390 TYR A CE1 1 
ATOM   2909  C  CE2 . TYR A 1 390 ? 253.445 267.258 235.688 1.00 21.39  ? 390 TYR A CE2 1 
ATOM   2910  C  CZ  . TYR A 1 390 ? 253.006 268.429 235.110 1.00 24.43  ? 390 TYR A CZ  1 
ATOM   2911  O  OH  . TYR A 1 390 ? 253.235 268.659 233.775 1.00 24.90  ? 390 TYR A OH  1 
ATOM   2912  N  N   . ASP A 1 391 ? 252.229 269.407 242.029 1.00 22.75  ? 391 ASP A N   1 
ATOM   2913  C  CA  . ASP A 1 391 ? 251.503 269.522 243.294 1.00 20.13  ? 391 ASP A CA  1 
ATOM   2914  C  C   . ASP A 1 391 ? 252.389 269.202 244.495 1.00 21.05  ? 391 ASP A C   1 
ATOM   2915  O  O   . ASP A 1 391 ? 251.931 268.640 245.491 1.00 26.91  ? 391 ASP A O   1 
ATOM   2916  C  CB  . ASP A 1 391 ? 250.257 268.634 243.297 1.00 19.21  ? 391 ASP A CB  1 
ATOM   2917  C  CG  . ASP A 1 391 ? 249.367 268.870 242.095 1.00 25.66  ? 391 ASP A CG  1 
ATOM   2918  O  OD1 . ASP A 1 391 ? 248.936 270.023 241.887 1.00 33.78  ? 391 ASP A OD1 1 
ATOM   2919  O  OD2 . ASP A 1 391 ? 249.103 267.901 241.354 1.00 31.34  ? 391 ASP A OD2 1 
ATOM   2920  N  N   . MET A 1 392 ? 253.669 269.566 244.411 1.00 23.08  ? 392 MET A N   1 
ATOM   2921  C  CA  . MET A 1 392 ? 254.527 269.450 245.584 1.00 20.55  ? 392 MET A CA  1 
ATOM   2922  C  C   . MET A 1 392 ? 254.147 270.457 246.658 1.00 21.20  ? 392 MET A C   1 
ATOM   2923  O  O   . MET A 1 392 ? 254.480 270.254 247.829 1.00 27.94  ? 392 MET A O   1 
ATOM   2924  C  CB  . MET A 1 392 ? 255.995 269.620 245.194 1.00 23.64  ? 392 MET A CB  1 
ATOM   2925  C  CG  . MET A 1 392 ? 256.532 268.513 244.298 1.00 23.49  ? 392 MET A CG  1 
ATOM   2926  S  SD  . MET A 1 392 ? 256.349 266.873 245.025 1.00 31.33  ? 392 MET A SD  1 
ATOM   2927  C  CE  . MET A 1 392 ? 257.851 266.746 245.988 1.00 17.10  ? 392 MET A CE  1 
ATOM   2928  N  N   . ALA A 1 393 ? 253.454 271.530 246.285 1.00 23.61  ? 393 ALA A N   1 
ATOM   2929  C  CA  . ALA A 1 393 ? 252.876 272.479 247.226 1.00 20.17  ? 393 ALA A CA  1 
ATOM   2930  C  C   . ALA A 1 393 ? 251.371 272.512 247.006 1.00 23.15  ? 393 ALA A C   1 
ATOM   2931  O  O   . ALA A 1 393 ? 250.912 272.776 245.890 1.00 22.73  ? 393 ALA A O   1 
ATOM   2932  C  CB  . ALA A 1 393 ? 253.481 273.873 247.050 1.00 21.07  ? 393 ALA A CB  1 
ATOM   2933  N  N   . GLY A 1 394 ? 250.611 272.239 248.060 1.00 25.16  ? 394 GLY A N   1 
ATOM   2934  C  CA  . GLY A 1 394 ? 249.167 272.284 247.974 1.00 19.27  ? 394 GLY A CA  1 
ATOM   2935  C  C   . GLY A 1 394 ? 248.547 270.991 247.477 1.00 21.28  ? 394 GLY A C   1 
ATOM   2936  O  O   . GLY A 1 394 ? 249.187 269.942 247.376 1.00 22.59  ? 394 GLY A O   1 
ATOM   2937  N  N   . ASN A 1 395 ? 247.258 271.090 247.150 1.00 20.21  ? 395 ASN A N   1 
ATOM   2938  C  CA  . ASN A 1 395 ? 246.432 269.930 246.835 1.00 20.25  ? 395 ASN A CA  1 
ATOM   2939  C  C   . ASN A 1 395 ? 246.273 269.066 248.080 1.00 18.94  ? 395 ASN A C   1 
ATOM   2940  O  O   . ASN A 1 395 ? 245.407 269.339 248.916 1.00 21.70  ? 395 ASN A O   1 
ATOM   2941  C  CB  . ASN A 1 395 ? 247.022 269.128 245.673 1.00 20.21  ? 395 ASN A CB  1 
ATOM   2942  C  CG  . ASN A 1 395 ? 246.028 268.935 244.542 1.00 18.88  ? 395 ASN A CG  1 
ATOM   2943  O  OD1 . ASN A 1 395 ? 245.190 269.797 244.290 1.00 23.86  ? 395 ASN A OD1 1 
ATOM   2944  N  ND2 . ASN A 1 395 ? 246.117 267.804 243.856 1.00 18.71  ? 395 ASN A ND2 1 
ATOM   2945  N  N   . VAL A 1 396 ? 247.088 268.025 248.217 1.00 19.53  ? 396 VAL A N   1 
ATOM   2946  C  CA  . VAL A 1 396 ? 247.101 267.197 249.417 1.00 18.44  ? 396 VAL A CA  1 
ATOM   2947  C  C   . VAL A 1 396 ? 248.510 267.179 249.991 1.00 18.86  ? 396 VAL A C   1 
ATOM   2948  O  O   . VAL A 1 396 ? 249.492 267.077 249.249 1.00 25.23  ? 396 VAL A O   1 
ATOM   2949  C  CB  . VAL A 1 396 ? 246.611 265.760 249.139 1.00 18.38  ? 396 VAL A CB  1 
ATOM   2950  C  CG1 . VAL A 1 396 ? 245.112 265.747 248.899 1.00 17.67  ? 396 VAL A CG1 1 
ATOM   2951  C  CG2 . VAL A 1 396 ? 247.355 265.158 247.964 1.00 19.38  ? 396 VAL A CG2 1 
ATOM   2952  N  N   . ALA A 1 397 ? 248.605 267.286 251.313 1.00 19.35  ? 397 ALA A N   1 
ATOM   2953  C  CA  . ALA A 1 397 ? 249.869 267.049 251.993 1.00 17.85  ? 397 ALA A CA  1 
ATOM   2954  C  C   . ALA A 1 397 ? 250.213 265.566 251.923 1.00 20.22  ? 397 ALA A C   1 
ATOM   2955  O  O   . ALA A 1 397 ? 249.333 264.709 251.835 1.00 22.49  ? 397 ALA A O   1 
ATOM   2956  C  CB  . ALA A 1 397 ? 249.794 267.514 253.445 1.00 15.70  ? 397 ALA A CB  1 
ATOM   2957  N  N   . GLU A 1 398 ? 251.505 265.262 251.964 1.00 22.54  ? 398 GLU A N   1 
ATOM   2958  C  CA  . GLU A 1 398 ? 251.990 263.943 251.583 1.00 20.53  ? 398 GLU A CA  1 
ATOM   2959  C  C   . GLU A 1 398 ? 252.730 263.266 252.728 1.00 20.76  ? 398 GLU A C   1 
ATOM   2960  O  O   . GLU A 1 398 ? 253.528 263.895 253.428 1.00 25.07  ? 398 GLU A O   1 
ATOM   2961  C  CB  . GLU A 1 398 ? 252.891 264.048 250.351 1.00 23.17  ? 398 GLU A CB  1 
ATOM   2962  C  CG  . GLU A 1 398 ? 252.128 264.457 249.102 1.00 22.14  ? 398 GLU A CG  1 
ATOM   2963  C  CD  . GLU A 1 398 ? 252.960 265.271 248.137 1.00 23.02  ? 398 GLU A CD  1 
ATOM   2964  O  OE1 . GLU A 1 398 ? 254.125 264.902 247.899 1.00 25.62  ? 398 GLU A OE1 1 
ATOM   2965  O  OE2 . GLU A 1 398 ? 252.447 266.283 247.618 1.00 24.38  ? 398 GLU A OE2 1 
ATOM   2966  N  N   . TRP A 1 399 ? 252.452 261.976 252.906 1.00 21.57  ? 399 TRP A N   1 
ATOM   2967  C  CA  . TRP A 1 399 ? 253.132 261.167 253.906 1.00 18.29  ? 399 TRP A CA  1 
ATOM   2968  C  C   . TRP A 1 399 ? 254.608 260.991 253.569 1.00 17.33  ? 399 TRP A C   1 
ATOM   2969  O  O   . TRP A 1 399 ? 255.009 260.973 252.403 1.00 22.25  ? 399 TRP A O   1 
ATOM   2970  C  CB  . TRP A 1 399 ? 252.489 259.783 254.009 1.00 17.68  ? 399 TRP A CB  1 
ATOM   2971  C  CG  . TRP A 1 399 ? 251.195 259.714 254.754 1.00 16.25  ? 399 TRP A CG  1 
ATOM   2972  C  CD1 . TRP A 1 399 ? 249.979 259.377 254.244 1.00 17.46  ? 399 TRP A CD1 1 
ATOM   2973  C  CD2 . TRP A 1 399 ? 250.996 259.940 256.153 1.00 15.74  ? 399 TRP A CD2 1 
ATOM   2974  N  NE1 . TRP A 1 399 ? 249.028 259.401 255.233 1.00 16.03  ? 399 TRP A NE1 1 
ATOM   2975  C  CE2 . TRP A 1 399 ? 249.628 259.739 256.416 1.00 15.98  ? 399 TRP A CE2 1 
ATOM   2976  C  CE3 . TRP A 1 399 ? 251.838 260.303 257.208 1.00 15.30  ? 399 TRP A CE3 1 
ATOM   2977  C  CZ2 . TRP A 1 399 ? 249.083 259.889 257.687 1.00 13.71  ? 399 TRP A CZ2 1 
ATOM   2978  C  CZ3 . TRP A 1 399 ? 251.296 260.449 258.468 1.00 15.44  ? 399 TRP A CZ3 1 
ATOM   2979  C  CH2 . TRP A 1 399 ? 249.932 260.243 258.698 1.00 16.42  ? 399 TRP A CH2 1 
ATOM   2980  N  N   . THR A 1 400 ? 255.418 260.853 254.615 1.00 20.33  ? 400 THR A N   1 
ATOM   2981  C  CA  . THR A 1 400 ? 256.804 260.433 254.491 1.00 21.32  ? 400 THR A CA  1 
ATOM   2982  C  C   . THR A 1 400 ? 257.058 259.298 255.473 1.00 25.02  ? 400 THR A C   1 
ATOM   2983  O  O   . THR A 1 400 ? 256.310 259.100 256.433 1.00 27.05  ? 400 THR A O   1 
ATOM   2984  C  CB  . THR A 1 400 ? 257.788 261.584 254.753 1.00 24.38  ? 400 THR A CB  1 
ATOM   2985  O  OG1 . THR A 1 400 ? 258.047 261.686 256.158 1.00 26.93  ? 400 THR A OG1 1 
ATOM   2986  C  CG2 . THR A 1 400 ? 257.220 262.901 254.253 1.00 19.92  ? 400 THR A CG2 1 
ATOM   2987  N  N   . SER A 1 401 ? 258.130 258.548 255.224 1.00 25.04  ? 401 SER A N   1 
ATOM   2988  C  CA  . SER A 1 401 ? 258.481 257.418 256.074 1.00 23.22  ? 401 SER A CA  1 
ATOM   2989  C  C   . SER A 1 401 ? 259.171 257.832 257.366 1.00 25.68  ? 401 SER A C   1 
ATOM   2990  O  O   . SER A 1 401 ? 259.405 256.976 258.226 1.00 31.66  ? 401 SER A O   1 
ATOM   2991  C  CB  . SER A 1 401 ? 259.377 256.448 255.304 1.00 24.47  ? 401 SER A CB  1 
ATOM   2992  O  OG  . SER A 1 401 ? 260.557 257.096 254.868 1.00 26.93  ? 401 SER A OG  1 
ATOM   2993  N  N   . THR A 1 402 ? 259.487 259.112 257.529 1.00 25.46  ? 402 THR A N   1 
ATOM   2994  C  CA  . THR A 1 402 ? 260.244 259.575 258.684 1.00 22.55  ? 402 THR A CA  1 
ATOM   2995  C  C   . THR A 1 402 ? 259.342 259.719 259.902 1.00 25.29  ? 402 THR A C   1 
ATOM   2996  O  O   . THR A 1 402 ? 258.267 260.321 259.824 1.00 24.51  ? 402 THR A O   1 
ATOM   2997  C  CB  . THR A 1 402 ? 260.914 260.912 258.371 1.00 26.96  ? 402 THR A CB  1 
ATOM   2998  O  OG1 . THR A 1 402 ? 261.726 260.779 257.199 1.00 32.58  ? 402 THR A OG1 1 
ATOM   2999  C  CG2 . THR A 1 402 ? 261.776 261.365 259.535 1.00 22.89  ? 402 THR A CG2 1 
ATOM   3000  N  N   . ALA A 1 403 ? 259.781 259.163 261.027 1.00 27.95  ? 403 ALA A N   1 
ATOM   3001  C  CA  . ALA A 1 403 ? 259.109 259.411 262.292 1.00 25.15  ? 403 ALA A CA  1 
ATOM   3002  C  C   . ALA A 1 403 ? 259.354 260.848 262.737 1.00 27.52  ? 403 ALA A C   1 
ATOM   3003  O  O   . ALA A 1 403 ? 260.417 261.424 262.493 1.00 32.44  ? 403 ALA A O   1 
ATOM   3004  C  CB  . ALA A 1 403 ? 259.595 258.436 263.363 1.00 19.69  ? 403 ALA A CB  1 
ATOM   3005  N  N   . PHE A 1 404 ? 258.358 261.429 263.397 1.00 25.61  ? 404 PHE A N   1 
ATOM   3006  C  CA  . PHE A 1 404 ? 258.404 262.839 263.754 1.00 27.11  ? 404 PHE A CA  1 
ATOM   3007  C  C   . PHE A 1 404 ? 259.084 263.040 265.102 1.00 32.35  ? 404 PHE A C   1 
ATOM   3008  O  O   . PHE A 1 404 ? 258.727 262.395 266.092 1.00 35.00  ? 404 PHE A O   1 
ATOM   3009  C  CB  . PHE A 1 404 ? 257.001 263.444 263.786 1.00 23.62  ? 404 PHE A CB  1 
ATOM   3010  C  CG  . PHE A 1 404 ? 256.972 264.845 264.317 1.00 28.30  ? 404 PHE A CG  1 
ATOM   3011  C  CD1 . PHE A 1 404 ? 257.348 265.910 263.518 1.00 29.46  ? 404 PHE A CD1 1 
ATOM   3012  C  CD2 . PHE A 1 404 ? 256.583 265.097 265.620 1.00 30.98  ? 404 PHE A CD2 1 
ATOM   3013  C  CE1 . PHE A 1 404 ? 257.334 267.197 264.008 1.00 33.06  ? 404 PHE A CE1 1 
ATOM   3014  C  CE2 . PHE A 1 404 ? 256.564 266.382 266.114 1.00 30.46  ? 404 PHE A CE2 1 
ATOM   3015  C  CZ  . PHE A 1 404 ? 256.940 267.434 265.307 1.00 31.54  ? 404 PHE A CZ  1 
ATOM   3016  N  N   . SER A 1 405 ? 260.065 263.938 265.127 1.00 31.42  ? 405 SER A N   1 
ATOM   3017  C  CA  . SER A 1 405 ? 260.713 264.382 266.351 1.00 28.60  ? 405 SER A CA  1 
ATOM   3018  C  C   . SER A 1 405 ? 260.929 265.884 266.257 1.00 33.97  ? 405 SER A C   1 
ATOM   3019  O  O   . SER A 1 405 ? 261.312 266.394 265.201 1.00 36.33  ? 405 SER A O   1 
ATOM   3020  C  CB  . SER A 1 405 ? 262.049 263.661 266.575 1.00 35.52  ? 405 SER A CB  1 
ATOM   3021  O  OG  . SER A 1 405 ? 262.433 263.699 267.939 1.00 37.69  ? 405 SER A OG  1 
ATOM   3022  N  N   . GLU A 1 406 ? 260.682 266.591 267.361 1.00 38.66  ? 406 GLU A N   1 
ATOM   3023  C  CA  . GLU A 1 406 ? 260.858 268.040 267.348 1.00 39.91  ? 406 GLU A CA  1 
ATOM   3024  C  C   . GLU A 1 406 ? 262.287 268.422 266.997 1.00 41.68  ? 406 GLU A C   1 
ATOM   3025  O  O   . GLU A 1 406 ? 262.515 269.463 266.371 1.00 43.27  ? 406 GLU A O   1 
ATOM   3026  C  CB  . GLU A 1 406 ? 260.455 268.634 268.697 1.00 43.82  ? 406 GLU A CB  1 
ATOM   3027  C  CG  . GLU A 1 406 ? 258.955 268.652 268.923 1.00 48.72  ? 406 GLU A CG  1 
ATOM   3028  C  CD  . GLU A 1 406 ? 258.237 269.574 267.957 1.00 56.88  ? 406 GLU A CD  1 
ATOM   3029  O  OE1 . GLU A 1 406 ? 258.922 270.269 267.179 1.00 59.72  ? 406 GLU A OE1 1 
ATOM   3030  O  OE2 . GLU A 1 406 ? 256.988 269.602 267.970 1.00 57.54  ? 406 GLU A OE2 1 
ATOM   3031  N  N   . SER A 1 407 ? 263.256 267.601 267.389 1.00 41.05  ? 407 SER A N   1 
ATOM   3032  C  CA  . SER A 1 407 ? 264.640 267.729 266.942 1.00 36.96  ? 407 SER A CA  1 
ATOM   3033  C  C   . SER A 1 407 ? 264.966 266.462 266.161 1.00 39.53  ? 407 SER A C   1 
ATOM   3034  O  O   . SER A 1 407 ? 265.509 265.500 266.705 1.00 43.90  ? 407 SER A O   1 
ATOM   3035  C  CB  . SER A 1 407 ? 265.589 267.930 268.123 1.00 41.85  ? 407 SER A CB  1 
ATOM   3036  O  OG  . SER A 1 407 ? 265.550 266.821 269.003 1.00 43.02  ? 407 SER A OG  1 
ATOM   3037  N  N   . GLY A 1 408 ? 264.630 266.470 264.875 1.00 41.48  ? 408 GLY A N   1 
ATOM   3038  C  CA  . GLY A 1 408 ? 264.878 265.330 264.017 1.00 33.76  ? 408 GLY A CA  1 
ATOM   3039  C  C   . GLY A 1 408 ? 265.912 265.645 262.963 1.00 36.33  ? 408 GLY A C   1 
ATOM   3040  O  O   . GLY A 1 408 ? 266.645 264.763 262.509 1.00 37.17  ? 408 GLY A O   1 
ATOM   3041  N  N   . LEU A 1 409 ? 265.976 266.916 262.564 1.00 37.23  ? 409 LEU A N   1 
ATOM   3042  C  CA  . LEU A 1 409 ? 267.019 267.349 261.643 1.00 33.34  ? 409 LEU A CA  1 
ATOM   3043  C  C   . LEU A 1 409 ? 268.397 267.179 262.268 1.00 36.29  ? 409 LEU A C   1 
ATOM   3044  O  O   . LEU A 1 409 ? 269.363 266.837 261.578 1.00 42.97  ? 409 LEU A O   1 
ATOM   3045  C  CB  . LEU A 1 409 ? 266.784 268.803 261.235 1.00 34.22  ? 409 LEU A CB  1 
ATOM   3046  C  CG  . LEU A 1 409 ? 266.017 269.039 259.933 1.00 38.12  ? 409 LEU A CG  1 
ATOM   3047  C  CD1 . LEU A 1 409 ? 264.631 268.418 260.004 1.00 32.93  ? 409 LEU A CD1 1 
ATOM   3048  C  CD2 . LEU A 1 409 ? 265.930 270.525 259.621 1.00 37.35  ? 409 LEU A CD2 1 
ATOM   3049  N  N   . LYS A 1 410 ? 268.506 267.417 263.577 1.00 35.76  ? 410 LYS A N   1 
ATOM   3050  C  CA  . LYS A 1 410 ? 269.779 267.267 264.270 1.00 33.00  ? 410 LYS A CA  1 
ATOM   3051  C  C   . LYS A 1 410 ? 270.152 265.807 264.497 1.00 33.54  ? 410 LYS A C   1 
ATOM   3052  O  O   . LYS A 1 410 ? 271.342 265.480 264.537 1.00 40.78  ? 410 LYS A O   1 
ATOM   3053  C  CB  . LYS A 1 410 ? 269.734 267.999 265.612 1.00 38.39  ? 410 LYS A CB  1 
ATOM   3054  C  CG  . LYS A 1 410 ? 269.922 269.500 265.512 1.00 42.72  ? 410 LYS A CG  1 
ATOM   3055  C  CD  . LYS A 1 410 ? 271.327 269.910 265.913 1.00 45.17  ? 410 LYS A CD  1 
ATOM   3056  C  CE  . LYS A 1 410 ? 271.588 271.367 265.573 1.00 52.72  ? 410 LYS A CE  1 
ATOM   3057  N  NZ  . LYS A 1 410 ? 271.852 272.179 266.791 1.00 46.06  ? 410 LYS A NZ  1 
ATOM   3058  N  N   . GLN A 1 411 ? 269.169 264.923 264.649 1.00 34.22  ? 411 GLN A N   1 
ATOM   3059  C  CA  . GLN A 1 411 ? 269.443 263.533 264.987 1.00 33.29  ? 411 GLN A CA  1 
ATOM   3060  C  C   . GLN A 1 411 ? 269.613 262.632 263.772 1.00 34.07  ? 411 GLN A C   1 
ATOM   3061  O  O   . GLN A 1 411 ? 269.994 261.469 263.936 1.00 34.22  ? 411 GLN A O   1 
ATOM   3062  C  CB  . GLN A 1 411 ? 268.329 262.973 265.875 1.00 34.82  ? 411 GLN A CB  1 
ATOM   3063  C  CG  . GLN A 1 411 ? 268.254 263.613 267.247 1.00 35.46  ? 411 GLN A CG  1 
ATOM   3064  C  CD  . GLN A 1 411 ? 266.943 263.334 267.944 1.00 40.36  ? 411 GLN A CD  1 
ATOM   3065  O  OE1 . GLN A 1 411 ? 265.931 263.065 267.300 1.00 44.60  ? 411 GLN A OE1 1 
ATOM   3066  N  NE2 . GLN A 1 411 ? 266.951 263.400 269.270 1.00 42.41  ? 411 GLN A NE2 1 
ATOM   3067  N  N   . MET A 1 412 ? 269.344 263.126 262.570 1.00 36.26  ? 412 MET A N   1 
ATOM   3068  C  CA  . MET A 1 412 ? 269.526 262.321 261.374 1.00 33.75  ? 412 MET A CA  1 
ATOM   3069  C  C   . MET A 1 412 ? 270.968 262.410 260.881 1.00 35.05  ? 412 MET A C   1 
ATOM   3070  O  O   . MET A 1 412 ? 271.780 263.191 261.381 1.00 39.85  ? 412 MET A O   1 
ATOM   3071  C  CB  . MET A 1 412 ? 268.553 262.758 260.279 1.00 29.17  ? 412 MET A CB  1 
ATOM   3072  C  CG  . MET A 1 412 ? 267.098 262.479 260.607 1.00 36.50  ? 412 MET A CG  1 
ATOM   3073  S  SD  . MET A 1 412 ? 265.983 262.831 259.238 1.00 50.04  ? 412 MET A SD  1 
ATOM   3074  C  CE  . MET A 1 412 ? 266.606 264.420 258.700 1.00 33.10  ? 412 MET A CE  1 
ATOM   3075  N  N   . SER A 1 413 ? 271.283 261.585 259.888 1.00 33.38  ? 413 SER A N   1 
ATOM   3076  C  CA  . SER A 1 413 ? 272.614 261.555 259.307 1.00 29.95  ? 413 SER A CA  1 
ATOM   3077  C  C   . SER A 1 413 ? 272.764 262.636 258.238 1.00 33.75  ? 413 SER A C   1 
ATOM   3078  O  O   . SER A 1 413 ? 271.793 263.245 257.781 1.00 34.59  ? 413 SER A O   1 
ATOM   3079  C  CB  . SER A 1 413 ? 272.904 260.179 258.711 1.00 30.18  ? 413 SER A CB  1 
ATOM   3080  O  OG  . SER A 1 413 ? 274.286 260.013 258.453 1.00 32.48  ? 413 SER A OG  1 
ATOM   3081  N  N   . ASP A 1 414 ? 274.015 262.867 257.838 1.00 37.19  ? 414 ASP A N   1 
ATOM   3082  C  CA  . ASP A 1 414 ? 274.313 263.813 256.769 1.00 33.78  ? 414 ASP A CA  1 
ATOM   3083  C  C   . ASP A 1 414 ? 273.989 263.253 255.393 1.00 28.62  ? 414 ASP A C   1 
ATOM   3084  O  O   . ASP A 1 414 ? 273.612 264.011 254.493 1.00 28.93  ? 414 ASP A O   1 
ATOM   3085  C  CB  . ASP A 1 414 ? 275.787 264.211 256.819 1.00 35.57  ? 414 ASP A CB  1 
ATOM   3086  C  CG  . ASP A 1 414 ? 275.986 265.653 257.206 1.00 45.44  ? 414 ASP A CG  1 
ATOM   3087  O  OD1 . ASP A 1 414 ? 277.152 266.068 257.359 1.00 47.08  ? 414 ASP A OD1 1 
ATOM   3088  O  OD2 . ASP A 1 414 ? 274.978 266.373 257.349 1.00 48.40  ? 414 ASP A OD2 1 
ATOM   3089  N  N   . ILE A 1 415 ? 274.146 261.947 255.204 1.00 27.96  ? 415 ILE A N   1 
ATOM   3090  C  CA  . ILE A 1 415 ? 273.957 261.298 253.913 1.00 26.82  ? 415 ILE A CA  1 
ATOM   3091  C  C   . ILE A 1 415 ? 272.728 260.408 254.001 1.00 29.64  ? 415 ILE A C   1 
ATOM   3092  O  O   . ILE A 1 415 ? 272.599 259.608 254.936 1.00 32.60  ? 415 ILE A O   1 
ATOM   3093  C  CB  . ILE A 1 415 ? 275.200 260.488 253.502 1.00 30.34  ? 415 ILE A CB  1 
ATOM   3094  C  CG1 . ILE A 1 415 ? 274.839 259.467 252.421 1.00 32.42  ? 415 ILE A CG1 1 
ATOM   3095  C  CG2 . ILE A 1 415 ? 275.828 259.812 254.711 1.00 28.80  ? 415 ILE A CG2 1 
ATOM   3096  C  CD1 . ILE A 1 415 ? 275.983 258.566 252.023 1.00 40.69  ? 415 ILE A CD1 1 
ATOM   3097  N  N   . ASN A 1 416 ? 271.831 260.548 253.030 1.00 29.05  ? 416 ASN A N   1 
ATOM   3098  C  CA  . ASN A 1 416 ? 270.572 259.813 252.999 1.00 24.34  ? 416 ASN A CA  1 
ATOM   3099  C  C   . ASN A 1 416 ? 269.879 259.860 254.362 1.00 30.24  ? 416 ASN A C   1 
ATOM   3100  O  O   . ASN A 1 416 ? 269.600 258.813 254.960 1.00 35.63  ? 416 ASN A O   1 
ATOM   3101  C  CB  . ASN A 1 416 ? 270.792 258.374 252.555 1.00 26.56  ? 416 ASN A CB  1 
ATOM   3102  C  CG  . ASN A 1 416 ? 271.149 258.268 251.091 1.00 27.68  ? 416 ASN A CG  1 
ATOM   3103  O  OD1 . ASN A 1 416 ? 270.786 259.126 250.287 1.00 28.81  ? 416 ASN A OD1 1 
ATOM   3104  N  ND2 . ASN A 1 416 ? 271.860 257.210 250.733 1.00 30.09  ? 416 ASN A ND2 1 
ATOM   3105  N  N   . PRO A 1 417 ? 269.592 261.052 254.880 1.00 30.45  ? 417 PRO A N   1 
ATOM   3106  C  CA  . PRO A 1 417 ? 269.038 261.152 256.234 1.00 29.57  ? 417 PRO A CA  1 
ATOM   3107  C  C   . PRO A 1 417 ? 267.725 260.395 256.359 1.00 31.47  ? 417 PRO A C   1 
ATOM   3108  O  O   . PRO A 1 417 ? 266.882 260.420 255.460 1.00 35.47  ? 417 PRO A O   1 
ATOM   3109  C  CB  . PRO A 1 417 ? 268.837 262.660 256.426 1.00 26.90  ? 417 PRO A CB  1 
ATOM   3110  C  CG  . PRO A 1 417 ? 269.685 263.306 255.379 1.00 26.34  ? 417 PRO A CG  1 
ATOM   3111  C  CD  . PRO A 1 417 ? 269.698 262.365 254.226 1.00 27.33  ? 417 PRO A CD  1 
ATOM   3112  N  N   . GLU A 1 418 ? 267.556 259.720 257.493 1.00 32.37  ? 418 GLU A N   1 
ATOM   3113  C  CA  . GLU A 1 418 ? 266.323 258.996 257.764 1.00 29.41  ? 418 GLU A CA  1 
ATOM   3114  C  C   . GLU A 1 418 ? 266.189 258.784 259.263 1.00 28.92  ? 418 GLU A C   1 
ATOM   3115  O  O   . GLU A 1 418 ? 267.149 258.377 259.922 1.00 35.02  ? 418 GLU A O   1 
ATOM   3116  C  CB  . GLU A 1 418 ? 266.296 257.652 257.028 1.00 28.12  ? 418 GLU A CB  1 
ATOM   3117  C  CG  . GLU A 1 418 ? 265.115 256.745 257.376 1.00 34.24  ? 418 GLU A CG  1 
ATOM   3118  C  CD  . GLU A 1 418 ? 263.754 257.414 257.216 1.00 33.46  ? 418 GLU A CD  1 
ATOM   3119  O  OE1 . GLU A 1 418 ? 263.693 258.653 257.081 1.00 34.07  ? 418 GLU A OE1 1 
ATOM   3120  O  OE2 . GLU A 1 418 ? 262.738 256.691 257.220 1.00 32.46  ? 418 GLU A OE2 1 
ATOM   3121  N  N   . LEU A 1 419 ? 265.002 259.063 259.792 1.00 32.08  ? 419 LEU A N   1 
ATOM   3122  C  CA  . LEU A 1 419 ? 264.651 258.778 261.179 1.00 29.56  ? 419 LEU A CA  1 
ATOM   3123  C  C   . LEU A 1 419 ? 263.512 257.767 261.130 1.00 27.64  ? 419 LEU A C   1 
ATOM   3124  O  O   . LEU A 1 419 ? 262.342 258.135 261.006 1.00 32.33  ? 419 LEU A O   1 
ATOM   3125  C  CB  . LEU A 1 419 ? 264.262 260.043 261.929 1.00 29.62  ? 419 LEU A CB  1 
ATOM   3126  C  CG  . LEU A 1 419 ? 264.544 260.047 263.431 1.00 30.78  ? 419 LEU A CG  1 
ATOM   3127  C  CD1 . LEU A 1 419 ? 265.965 259.592 263.708 1.00 32.53  ? 419 LEU A CD1 1 
ATOM   3128  C  CD2 . LEU A 1 419 ? 264.300 261.429 264.008 1.00 35.78  ? 419 LEU A CD2 1 
ATOM   3129  N  N   . GLU A 1 420 ? 263.861 256.491 261.228 1.00 28.38  ? 420 GLU A N   1 
ATOM   3130  C  CA  . GLU A 1 420 ? 262.914 255.401 261.055 1.00 31.73  ? 420 GLU A CA  1 
ATOM   3131  C  C   . GLU A 1 420 ? 262.556 254.810 262.409 1.00 31.20  ? 420 GLU A C   1 
ATOM   3132  O  O   . GLU A 1 420 ? 263.439 254.551 263.233 1.00 40.32  ? 420 GLU A O   1 
ATOM   3133  C  CB  . GLU A 1 420 ? 263.495 254.319 260.146 1.00 33.96  ? 420 GLU A CB  1 
ATOM   3134  C  CG  . GLU A 1 420 ? 262.471 253.333 259.628 1.00 39.44  ? 420 GLU A CG  1 
ATOM   3135  C  CD  . GLU A 1 420 ? 262.490 252.027 260.390 1.00 50.23  ? 420 GLU A CD  1 
ATOM   3136  O  OE1 . GLU A 1 420 ? 263.527 251.713 261.009 1.00 52.26  ? 420 GLU A OE1 1 
ATOM   3137  O  OE2 . GLU A 1 420 ? 261.467 251.311 260.369 1.00 51.00  ? 420 GLU A OE2 1 
ATOM   3138  N  N   . TYR A 1 421 ? 261.264 254.604 262.636 1.00 28.89  ? 421 TYR A N   1 
ATOM   3139  C  CA  . TYR A 1 421 ? 260.791 253.994 263.867 1.00 27.23  ? 421 TYR A CA  1 
ATOM   3140  C  C   . TYR A 1 421 ? 259.648 253.046 263.549 1.00 28.13  ? 421 TYR A C   1 
ATOM   3141  O  O   . TYR A 1 421 ? 258.699 253.423 262.856 1.00 32.16  ? 421 TYR A O   1 
ATOM   3142  C  CB  . TYR A 1 421 ? 260.333 255.052 264.873 1.00 27.18  ? 421 TYR A CB  1 
ATOM   3143  C  CG  . TYR A 1 421 ? 259.993 254.479 266.224 1.00 27.13  ? 421 TYR A CG  1 
ATOM   3144  C  CD1 . TYR A 1 421 ? 260.922 253.732 266.932 1.00 28.93  ? 421 TYR A CD1 1 
ATOM   3145  C  CD2 . TYR A 1 421 ? 258.741 254.671 266.785 1.00 28.44  ? 421 TYR A CD2 1 
ATOM   3146  C  CE1 . TYR A 1 421 ? 260.617 253.202 268.163 1.00 26.77  ? 421 TYR A CE1 1 
ATOM   3147  C  CE2 . TYR A 1 421 ? 258.427 254.144 268.017 1.00 28.49  ? 421 TYR A CE2 1 
ATOM   3148  C  CZ  . TYR A 1 421 ? 259.370 253.410 268.701 1.00 28.74  ? 421 TYR A CZ  1 
ATOM   3149  O  OH  . TYR A 1 421 ? 259.068 252.880 269.930 1.00 35.56  ? 421 TYR A OH  1 
ATOM   3150  N  N   . LYS A 1 422 ? 259.747 251.819 264.048 1.00 28.40  ? 422 LYS A N   1 
ATOM   3151  C  CA  . LYS A 1 422 ? 258.664 250.844 263.968 1.00 28.77  ? 422 LYS A CA  1 
ATOM   3152  C  C   . LYS A 1 422 ? 258.045 250.757 265.356 1.00 29.00  ? 422 LYS A C   1 
ATOM   3153  O  O   . LYS A 1 422 ? 258.520 250.012 266.216 1.00 33.85  ? 422 LYS A O   1 
ATOM   3154  C  CB  . LYS A 1 422 ? 259.177 249.493 263.486 1.00 27.37  ? 422 LYS A CB  1 
ATOM   3155  C  CG  . LYS A 1 422 ? 259.427 249.428 261.992 1.00 29.49  ? 422 LYS A CG  1 
ATOM   3156  C  CD  . LYS A 1 422 ? 259.997 248.082 261.587 1.00 32.70  ? 422 LYS A CD  1 
ATOM   3157  C  CE  . LYS A 1 422 ? 261.370 248.230 260.962 1.00 36.50  ? 422 LYS A CE  1 
ATOM   3158  N  NZ  . LYS A 1 422 ? 261.321 248.084 259.485 1.00 37.97  ? 422 LYS A NZ  1 
ATOM   3159  N  N   . ALA A 1 423 ? 256.982 251.525 265.573 1.00 29.96  ? 423 ALA A N   1 
ATOM   3160  C  CA  . ALA A 1 423 ? 256.369 251.596 266.891 1.00 30.15  ? 423 ALA A CA  1 
ATOM   3161  C  C   . ALA A 1 423 ? 255.773 250.252 267.284 1.00 31.43  ? 423 ALA A C   1 
ATOM   3162  O  O   . ALA A 1 423 ? 255.264 249.507 266.443 1.00 39.20  ? 423 ALA A O   1 
ATOM   3163  C  CB  . ALA A 1 423 ? 255.288 252.678 266.913 1.00 27.47  ? 423 ALA A CB  1 
ATOM   3164  N  N   . ALA A 1 424 ? 255.847 249.940 268.573 1.00 28.61  ? 424 ALA A N   1 
ATOM   3165  C  CA  . ALA A 1 424 ? 255.190 248.755 269.093 1.00 29.52  ? 424 ALA A CA  1 
ATOM   3166  C  C   . ALA A 1 424 ? 253.697 249.016 269.274 1.00 33.98  ? 424 ALA A C   1 
ATOM   3167  O  O   . ALA A 1 424 ? 253.249 250.159 269.396 1.00 37.41  ? 424 ALA A O   1 
ATOM   3168  C  CB  . ALA A 1 424 ? 255.820 248.323 270.417 1.00 27.25  ? 424 ALA A CB  1 
ATOM   3169  N  N   . LEU A 1 425 ? 252.922 247.931 269.287 1.00 33.89  ? 425 LEU A N   1 
ATOM   3170  C  CA  . LEU A 1 425 ? 251.477 248.063 269.432 1.00 36.44  ? 425 LEU A CA  1 
ATOM   3171  C  C   . LEU A 1 425 ? 251.111 248.690 270.770 1.00 38.63  ? 425 LEU A C   1 
ATOM   3172  O  O   . LEU A 1 425 ? 250.177 249.497 270.852 1.00 38.45  ? 425 LEU A O   1 
ATOM   3173  C  CB  . LEU A 1 425 ? 250.805 246.700 269.278 1.00 37.76  ? 425 LEU A CB  1 
ATOM   3174  C  CG  . LEU A 1 425 ? 250.694 246.175 267.848 1.00 40.74  ? 425 LEU A CG  1 
ATOM   3175  C  CD1 . LEU A 1 425 ? 250.115 244.775 267.841 1.00 41.89  ? 425 LEU A CD1 1 
ATOM   3176  C  CD2 . LEU A 1 425 ? 249.855 247.112 266.995 1.00 41.67  ? 425 LEU A CD2 1 
ATOM   3177  N  N   . THR A 1 426 ? 251.833 248.335 271.828 1.00 35.97  ? 426 THR A N   1 
ATOM   3178  C  CA  . THR A 1 426 ? 251.567 248.853 273.161 1.00 34.18  ? 426 THR A CA  1 
ATOM   3179  C  C   . THR A 1 426 ? 252.316 250.145 273.454 1.00 36.92  ? 426 THR A C   1 
ATOM   3180  O  O   . THR A 1 426 ? 252.252 250.639 274.585 1.00 39.07  ? 426 THR A O   1 
ATOM   3181  C  CB  . THR A 1 426 ? 251.924 247.802 274.215 1.00 38.70  ? 426 THR A CB  1 
ATOM   3182  O  OG1 . THR A 1 426 ? 253.183 247.203 273.885 1.00 44.17  ? 426 THR A OG1 1 
ATOM   3183  C  CG2 . THR A 1 426 ? 250.857 246.725 274.266 1.00 36.04  ? 426 THR A CG2 1 
ATOM   3184  N  N   . ASP A 1 427 ? 253.020 250.701 272.472 1.00 33.27  ? 427 ASP A N   1 
ATOM   3185  C  CA  . ASP A 1 427 ? 253.709 251.963 272.672 1.00 31.89  ? 427 ASP A CA  1 
ATOM   3186  C  C   . ASP A 1 427 ? 252.703 253.082 272.937 1.00 35.32  ? 427 ASP A C   1 
ATOM   3187  O  O   . ASP A 1 427 ? 251.568 253.037 272.456 1.00 40.26  ? 427 ASP A O   1 
ATOM   3188  C  CB  . ASP A 1 427 ? 254.553 252.310 271.448 1.00 32.57  ? 427 ASP A CB  1 
ATOM   3189  C  CG  . ASP A 1 427 ? 256.005 251.933 271.618 1.00 34.19  ? 427 ASP A CG  1 
ATOM   3190  O  OD1 . ASP A 1 427 ? 256.366 251.420 272.695 1.00 38.82  ? 427 ASP A OD1 1 
ATOM   3191  O  OD2 . ASP A 1 427 ? 256.784 252.150 270.671 1.00 32.40  ? 427 ASP A OD2 1 
ATOM   3192  N  N   . PRO A 1 428 ? 253.091 254.095 273.709 1.00 36.28  ? 428 PRO A N   1 
ATOM   3193  C  CA  . PRO A 1 428 ? 252.213 255.255 273.886 1.00 33.71  ? 428 PRO A CA  1 
ATOM   3194  C  C   . PRO A 1 428 ? 251.914 255.919 272.551 1.00 35.47  ? 428 PRO A C   1 
ATOM   3195  O  O   . PRO A 1 428 ? 252.752 255.962 271.649 1.00 34.93  ? 428 PRO A O   1 
ATOM   3196  C  CB  . PRO A 1 428 ? 253.017 256.179 274.811 1.00 32.62  ? 428 PRO A CB  1 
ATOM   3197  C  CG  . PRO A 1 428 ? 254.416 255.654 274.782 1.00 33.54  ? 428 PRO A CG  1 
ATOM   3198  C  CD  . PRO A 1 428 ? 254.303 254.190 274.535 1.00 33.58  ? 428 PRO A CD  1 
ATOM   3199  N  N   . TYR A 1 429 ? 250.693 256.441 272.437 1.00 38.82  ? 429 TYR A N   1 
ATOM   3200  C  CA  . TYR A 1 429 ? 250.225 256.981 271.165 1.00 32.16  ? 429 TYR A CA  1 
ATOM   3201  C  C   . TYR A 1 429 ? 251.130 258.093 270.650 1.00 32.29  ? 429 TYR A C   1 
ATOM   3202  O  O   . TYR A 1 429 ? 251.183 258.337 269.439 1.00 31.68  ? 429 TYR A O   1 
ATOM   3203  C  CB  . TYR A 1 429 ? 248.792 257.489 271.323 1.00 30.96  ? 429 TYR A CB  1 
ATOM   3204  C  CG  . TYR A 1 429 ? 248.045 257.665 270.024 1.00 31.09  ? 429 TYR A CG  1 
ATOM   3205  C  CD1 . TYR A 1 429 ? 248.080 256.687 269.042 1.00 32.58  ? 429 TYR A CD1 1 
ATOM   3206  C  CD2 . TYR A 1 429 ? 247.296 258.807 269.784 1.00 27.47  ? 429 TYR A CD2 1 
ATOM   3207  C  CE1 . TYR A 1 429 ? 247.395 256.843 267.856 1.00 27.73  ? 429 TYR A CE1 1 
ATOM   3208  C  CE2 . TYR A 1 429 ? 246.608 258.971 268.603 1.00 25.97  ? 429 TYR A CE2 1 
ATOM   3209  C  CZ  . TYR A 1 429 ? 246.660 257.987 267.642 1.00 27.11  ? 429 TYR A CZ  1 
ATOM   3210  O  OH  . TYR A 1 429 ? 245.975 258.151 266.463 1.00 32.51  ? 429 TYR A OH  1 
ATOM   3211  N  N   . ILE A 1 430 ? 251.845 258.779 271.545 1.00 35.03  ? 430 ILE A N   1 
ATOM   3212  C  CA  . ILE A 1 430 ? 252.683 259.899 271.134 1.00 34.99  ? 430 ILE A CA  1 
ATOM   3213  C  C   . ILE A 1 430 ? 253.861 259.457 270.277 1.00 32.81  ? 430 ILE A C   1 
ATOM   3214  O  O   . ILE A 1 430 ? 254.441 260.279 269.558 1.00 32.39  ? 430 ILE A O   1 
ATOM   3215  C  CB  . ILE A 1 430 ? 253.180 260.676 272.367 1.00 36.00  ? 430 ILE A CB  1 
ATOM   3216  C  CG1 . ILE A 1 430 ? 253.953 261.924 271.937 1.00 38.28  ? 430 ILE A CG1 1 
ATOM   3217  C  CG2 . ILE A 1 430 ? 254.044 259.787 273.247 1.00 32.30  ? 430 ILE A CG2 1 
ATOM   3218  C  CD1 . ILE A 1 430 ? 253.084 263.146 271.756 1.00 38.37  ? 430 ILE A CD1 1 
ATOM   3219  N  N   . LEU A 1 431 ? 254.234 258.181 270.328 1.00 32.57  ? 431 LEU A N   1 
ATOM   3220  C  CA  . LEU A 1 431 ? 255.384 257.676 269.590 1.00 29.56  ? 431 LEU A CA  1 
ATOM   3221  C  C   . LEU A 1 431 ? 255.053 257.289 268.155 1.00 28.68  ? 431 LEU A C   1 
ATOM   3222  O  O   . LEU A 1 431 ? 255.952 256.867 267.422 1.00 29.88  ? 431 LEU A O   1 
ATOM   3223  C  CB  . LEU A 1 431 ? 255.986 256.468 270.317 1.00 27.62  ? 431 LEU A CB  1 
ATOM   3224  C  CG  . LEU A 1 431 ? 256.557 256.701 271.717 1.00 31.70  ? 431 LEU A CG  1 
ATOM   3225  C  CD1 . LEU A 1 431 ? 257.347 255.491 272.187 1.00 30.24  ? 431 LEU A CD1 1 
ATOM   3226  C  CD2 . LEU A 1 431 ? 257.423 257.948 271.745 1.00 30.02  ? 431 LEU A CD2 1 
ATOM   3227  N  N   . LYS A 1 432 ? 253.798 257.421 267.735 1.00 27.32  ? 432 LYS A N   1 
ATOM   3228  C  CA  . LYS A 1 432 ? 253.339 256.934 266.438 1.00 22.73  ? 432 LYS A CA  1 
ATOM   3229  C  C   . LYS A 1 432 ? 253.025 258.068 265.467 1.00 19.75  ? 432 LYS A C   1 
ATOM   3230  O  O   . LYS A 1 432 ? 252.115 257.962 264.644 1.00 24.96  ? 432 LYS A O   1 
ATOM   3231  C  CB  . LYS A 1 432 ? 252.119 256.034 266.609 1.00 23.97  ? 432 LYS A CB  1 
ATOM   3232  C  CG  . LYS A 1 432 ? 252.189 255.143 267.830 1.00 26.58  ? 432 LYS A CG  1 
ATOM   3233  C  CD  . LYS A 1 432 ? 251.271 253.946 267.693 1.00 29.26  ? 432 LYS A CD  1 
ATOM   3234  C  CE  . LYS A 1 432 ? 251.572 252.912 268.760 1.00 29.30  ? 432 LYS A CE  1 
ATOM   3235  N  NZ  . LYS A 1 432 ? 250.361 252.154 269.166 1.00 34.10  ? 432 LYS A NZ  1 
ATOM   3236  N  N   . GLN A 1 433 ? 253.773 259.162 265.540 1.00 21.89  ? 433 GLN A N   1 
ATOM   3237  C  CA  . GLN A 1 433 ? 253.572 260.293 264.645 1.00 21.89  ? 433 GLN A CA  1 
ATOM   3238  C  C   . GLN A 1 433 ? 254.601 260.274 263.523 1.00 22.70  ? 433 GLN A C   1 
ATOM   3239  O  O   . GLN A 1 433 ? 255.789 260.041 263.756 1.00 28.27  ? 433 GLN A O   1 
ATOM   3240  C  CB  . GLN A 1 433 ? 253.655 261.616 265.405 1.00 24.16  ? 433 GLN A CB  1 
ATOM   3241  C  CG  . GLN A 1 433 ? 252.796 261.665 266.650 1.00 26.78  ? 433 GLN A CG  1 
ATOM   3242  C  CD  . GLN A 1 433 ? 252.599 263.075 267.157 1.00 32.71  ? 433 GLN A CD  1 
ATOM   3243  O  OE1 . GLN A 1 433 ? 251.866 263.864 266.561 1.00 32.99  ? 433 GLN A OE1 1 
ATOM   3244  N  NE2 . GLN A 1 433 ? 253.261 263.404 268.258 1.00 32.40  ? 433 GLN A NE2 1 
ATOM   3245  N  N   . LYS A 1 434 ? 254.131 260.518 262.303 1.00 19.45  ? 434 LYS A N   1 
ATOM   3246  C  CA  . LYS A 1 434 ? 254.962 260.532 261.112 1.00 21.44  ? 434 LYS A CA  1 
ATOM   3247  C  C   . LYS A 1 434 ? 254.884 261.896 260.442 1.00 21.42  ? 434 LYS A C   1 
ATOM   3248  O  O   . LYS A 1 434 ? 253.849 262.572 260.485 1.00 25.20  ? 434 LYS A O   1 
ATOM   3249  C  CB  . LYS A 1 434 ? 254.537 259.447 260.119 1.00 18.66  ? 434 LYS A CB  1 
ATOM   3250  C  CG  . LYS A 1 434 ? 254.248 258.106 260.756 1.00 19.02  ? 434 LYS A CG  1 
ATOM   3251  C  CD  . LYS A 1 434 ? 255.526 257.342 261.034 1.00 18.31  ? 434 LYS A CD  1 
ATOM   3252  C  CE  . LYS A 1 434 ? 255.270 256.192 261.984 1.00 19.92  ? 434 LYS A CE  1 
ATOM   3253  N  NZ  . LYS A 1 434 ? 256.529 255.531 262.413 1.00 22.22  ? 434 LYS A NZ  1 
ATOM   3254  N  N   . VAL A 1 435 ? 255.993 262.281 259.810 1.00 23.24  ? 435 VAL A N   1 
ATOM   3255  C  CA  . VAL A 1 435 ? 256.117 263.605 259.215 1.00 23.89  ? 435 VAL A CA  1 
ATOM   3256  C  C   . VAL A 1 435 ? 255.275 263.702 257.951 1.00 22.27  ? 435 VAL A C   1 
ATOM   3257  O  O   . VAL A 1 435 ? 255.145 262.737 257.186 1.00 21.73  ? 435 VAL A O   1 
ATOM   3258  C  CB  . VAL A 1 435 ? 257.594 263.920 258.924 1.00 20.28  ? 435 VAL A CB  1 
ATOM   3259  C  CG1 . VAL A 1 435 ? 257.736 265.326 258.370 1.00 22.95  ? 435 VAL A CG1 1 
ATOM   3260  C  CG2 . VAL A 1 435 ? 258.426 263.755 260.184 1.00 21.61  ? 435 VAL A CG2 1 
ATOM   3261  N  N   . VAL A 1 436 ? 254.705 264.884 257.727 1.00 23.37  ? 436 VAL A N   1 
ATOM   3262  C  CA  . VAL A 1 436 ? 253.893 265.197 256.558 1.00 20.66  ? 436 VAL A CA  1 
ATOM   3263  C  C   . VAL A 1 436 ? 254.422 266.487 255.945 1.00 21.32  ? 436 VAL A C   1 
ATOM   3264  O  O   . VAL A 1 436 ? 254.851 267.399 256.664 1.00 28.68  ? 436 VAL A O   1 
ATOM   3265  C  CB  . VAL A 1 436 ? 252.398 265.327 256.918 1.00 21.75  ? 436 VAL A CB  1 
ATOM   3266  C  CG1 . VAL A 1 436 ? 251.600 265.810 255.722 1.00 22.91  ? 436 VAL A CG1 1 
ATOM   3267  C  CG2 . VAL A 1 436 ? 251.860 263.996 257.410 1.00 16.64  ? 436 VAL A CG2 1 
ATOM   3268  N  N   . ARG A 1 437 ? 254.405 266.557 254.616 1.00 18.60  ? 437 ARG A N   1 
ATOM   3269  C  CA  . ARG A 1 437 ? 255.081 267.619 253.888 1.00 20.13  ? 437 ARG A CA  1 
ATOM   3270  C  C   . ARG A 1 437 ? 254.192 268.170 252.784 1.00 20.71  ? 437 ARG A C   1 
ATOM   3271  O  O   . ARG A 1 437 ? 253.335 267.468 252.242 1.00 23.42  ? 437 ARG A O   1 
ATOM   3272  C  CB  . ARG A 1 437 ? 256.390 267.111 253.275 1.00 21.03  ? 437 ARG A CB  1 
ATOM   3273  C  CG  . ARG A 1 437 ? 257.433 266.738 254.304 1.00 22.10  ? 437 ARG A CG  1 
ATOM   3274  C  CD  . ARG A 1 437 ? 257.605 267.829 255.340 1.00 26.64  ? 437 ARG A CD  1 
ATOM   3275  N  NE  . ARG A 1 437 ? 258.965 267.869 255.859 1.00 33.77  ? 437 ARG A NE  1 
ATOM   3276  C  CZ  . ARG A 1 437 ? 259.905 268.706 255.445 1.00 28.76  ? 437 ARG A CZ  1 
ATOM   3277  N  NH1 . ARG A 1 437 ? 259.670 269.595 254.496 1.00 27.30  ? 437 ARG A NH1 1 
ATOM   3278  N  NH2 . ARG A 1 437 ? 261.112 268.650 255.999 1.00 28.60  ? 437 ARG A NH2 1 
ATOM   3279  N  N   . GLY A 1 438 ? 254.406 269.444 252.461 1.00 20.92  ? 438 GLY A N   1 
ATOM   3280  C  CA  . GLY A 1 438 ? 253.848 270.027 251.257 1.00 23.83  ? 438 GLY A CA  1 
ATOM   3281  C  C   . GLY A 1 438 ? 252.686 270.976 251.449 1.00 23.27  ? 438 GLY A C   1 
ATOM   3282  O  O   . GLY A 1 438 ? 252.547 271.944 250.697 1.00 27.54  ? 438 GLY A O   1 
ATOM   3283  N  N   . GLY A 1 439 ? 251.847 270.719 252.441 1.00 23.21  ? 439 GLY A N   1 
ATOM   3284  C  CA  . GLY A 1 439 ? 250.625 271.474 252.605 1.00 19.20  ? 439 GLY A CA  1 
ATOM   3285  C  C   . GLY A 1 439 ? 249.513 270.957 251.709 1.00 21.06  ? 439 GLY A C   1 
ATOM   3286  O  O   . GLY A 1 439 ? 249.724 270.174 250.786 1.00 24.74  ? 439 GLY A O   1 
ATOM   3287  N  N   . SER A 1 440 ? 248.298 271.419 251.993 1.00 21.40  ? 440 SER A N   1 
ATOM   3288  C  CA  . SER A 1 440 ? 247.132 270.926 251.270 1.00 15.95  ? 440 SER A CA  1 
ATOM   3289  C  C   . SER A 1 440 ? 246.245 272.060 250.777 1.00 19.98  ? 440 SER A C   1 
ATOM   3290  O  O   . SER A 1 440 ? 246.608 273.237 250.868 1.00 22.70  ? 440 SER A O   1 
ATOM   3291  C  CB  . SER A 1 440 ? 246.319 269.983 252.157 1.00 16.70  ? 440 SER A CB  1 
ATOM   3292  O  OG  . SER A 1 440 ? 246.022 270.595 253.398 1.00 20.60  ? 440 SER A OG  1 
ATOM   3293  N  N   . TRP A 1 441 ? 245.073 271.702 250.254 1.00 21.43  ? 441 TRP A N   1 
ATOM   3294  C  CA  . TRP A 1 441 ? 244.088 272.666 249.784 1.00 16.61  ? 441 TRP A CA  1 
ATOM   3295  C  C   . TRP A 1 441 ? 243.543 273.550 250.898 1.00 19.08  ? 441 TRP A C   1 
ATOM   3296  O  O   . TRP A 1 441 ? 242.933 274.582 250.601 1.00 25.62  ? 441 TRP A O   1 
ATOM   3297  C  CB  . TRP A 1 441 ? 242.936 271.925 249.103 1.00 16.17  ? 441 TRP A CB  1 
ATOM   3298  C  CG  . TRP A 1 441 ? 242.307 270.870 249.972 1.00 19.50  ? 441 TRP A CG  1 
ATOM   3299  C  CD1 . TRP A 1 441 ? 242.717 269.579 250.118 1.00 18.92  ? 441 TRP A CD1 1 
ATOM   3300  C  CD2 . TRP A 1 441 ? 241.158 271.022 250.814 1.00 21.02  ? 441 TRP A CD2 1 
ATOM   3301  N  NE1 . TRP A 1 441 ? 241.897 268.917 250.996 1.00 18.49  ? 441 TRP A NE1 1 
ATOM   3302  C  CE2 . TRP A 1 441 ? 240.931 269.781 251.438 1.00 18.51  ? 441 TRP A CE2 1 
ATOM   3303  C  CE3 . TRP A 1 441 ? 240.300 272.087 251.100 1.00 19.60  ? 441 TRP A CE3 1 
ATOM   3304  C  CZ2 . TRP A 1 441 ? 239.883 269.577 252.328 1.00 19.66  ? 441 TRP A CZ2 1 
ATOM   3305  C  CZ3 . TRP A 1 441 ? 239.262 271.881 251.984 1.00 19.15  ? 441 TRP A CZ3 1 
ATOM   3306  C  CH2 . TRP A 1 441 ? 239.061 270.637 252.587 1.00 20.45  ? 441 TRP A CH2 1 
ATOM   3307  N  N   . LYS A 1 442 ? 243.742 273.174 252.160 1.00 16.53  ? 442 LYS A N   1 
ATOM   3308  C  CA  . LYS A 1 442 ? 243.191 273.900 253.296 1.00 19.58  ? 442 LYS A CA  1 
ATOM   3309  C  C   . LYS A 1 442 ? 244.269 274.572 254.140 1.00 25.85  ? 442 LYS A C   1 
ATOM   3310  O  O   . LYS A 1 442 ? 244.021 274.905 255.302 1.00 27.34  ? 442 LYS A O   1 
ATOM   3311  C  CB  . LYS A 1 442 ? 242.356 272.958 254.164 1.00 21.69  ? 442 LYS A CB  1 
ATOM   3312  C  CG  . LYS A 1 442 ? 243.126 271.757 254.677 1.00 19.71  ? 442 LYS A CG  1 
ATOM   3313  C  CD  . LYS A 1 442 ? 243.638 271.996 256.087 1.00 22.11  ? 442 LYS A CD  1 
ATOM   3314  C  CE  . LYS A 1 442 ? 244.972 271.314 256.309 1.00 22.17  ? 442 LYS A CE  1 
ATOM   3315  N  NZ  . LYS A 1 442 ? 245.490 271.546 257.680 1.00 23.59  ? 442 LYS A NZ  1 
ATOM   3316  N  N   . ASP A 1 443 ? 245.458 274.783 253.582 1.00 23.91  ? 443 ASP A N   1 
ATOM   3317  C  CA  . ASP A 1 443 ? 246.595 275.300 254.328 1.00 22.88  ? 443 ASP A CA  1 
ATOM   3318  C  C   . ASP A 1 443 ? 246.959 276.697 253.845 1.00 21.69  ? 443 ASP A C   1 
ATOM   3319  O  O   . ASP A 1 443 ? 246.876 276.993 252.650 1.00 24.19  ? 443 ASP A O   1 
ATOM   3320  C  CB  . ASP A 1 443 ? 247.805 274.372 254.189 1.00 23.23  ? 443 ASP A CB  1 
ATOM   3321  C  CG  . ASP A 1 443 ? 247.870 273.329 255.286 1.00 31.92  ? 443 ASP A CG  1 
ATOM   3322  O  OD1 . ASP A 1 443 ? 247.713 273.696 256.468 1.00 36.00  ? 443 ASP A OD1 1 
ATOM   3323  O  OD2 . ASP A 1 443 ? 248.080 272.141 254.968 1.00 32.53  ? 443 ASP A OD2 1 
ATOM   3324  N  N   . VAL A 1 444 ? 247.359 277.551 254.784 1.00 25.43  ? 444 VAL A N   1 
ATOM   3325  C  CA  . VAL A 1 444 ? 247.831 278.894 254.467 1.00 25.10  ? 444 VAL A CA  1 
ATOM   3326  C  C   . VAL A 1 444 ? 249.185 278.791 253.777 1.00 22.98  ? 444 VAL A C   1 
ATOM   3327  O  O   . VAL A 1 444 ? 249.799 277.719 253.752 1.00 27.42  ? 444 VAL A O   1 
ATOM   3328  C  CB  . VAL A 1 444 ? 247.910 279.774 255.728 1.00 23.05  ? 444 VAL A CB  1 
ATOM   3329  C  CG1 . VAL A 1 444 ? 246.524 279.990 256.309 1.00 23.21  ? 444 VAL A CG1 1 
ATOM   3330  C  CG2 . VAL A 1 444 ? 248.827 279.142 256.759 1.00 23.55  ? 444 VAL A CG2 1 
ATOM   3331  N  N   . ALA A 1 445 ? 249.659 279.903 253.210 1.00 25.54  ? 445 ALA A N   1 
ATOM   3332  C  CA  . ALA A 1 445 ? 250.884 279.867 252.416 1.00 25.78  ? 445 ALA A CA  1 
ATOM   3333  C  C   . ALA A 1 445 ? 252.079 279.390 253.229 1.00 30.82  ? 445 ALA A C   1 
ATOM   3334  O  O   . ALA A 1 445 ? 253.038 278.854 252.665 1.00 35.92  ? 445 ALA A O   1 
ATOM   3335  C  CB  . ALA A 1 445 ? 251.168 281.246 251.822 1.00 21.73  ? 445 ALA A CB  1 
ATOM   3336  N  N   . ARG A 1 446 ? 252.046 279.577 254.548 1.00 29.33  ? 446 ARG A N   1 
ATOM   3337  C  CA  . ARG A 1 446 ? 253.171 279.162 255.377 1.00 25.65  ? 446 ARG A CA  1 
ATOM   3338  C  C   . ARG A 1 446 ? 253.371 277.652 255.330 1.00 30.41  ? 446 ARG A C   1 
ATOM   3339  O  O   . ARG A 1 446 ? 254.509 277.171 255.287 1.00 32.04  ? 446 ARG A O   1 
ATOM   3340  C  CB  . ARG A 1 446 ? 252.959 279.626 256.816 1.00 28.57  ? 446 ARG A CB  1 
ATOM   3341  C  CG  . ARG A 1 446 ? 254.193 279.509 257.684 1.00 37.05  ? 446 ARG A CG  1 
ATOM   3342  C  CD  . ARG A 1 446 ? 253.858 278.890 259.025 1.00 34.09  ? 446 ARG A CD  1 
ATOM   3343  N  NE  . ARG A 1 446 ? 255.049 278.703 259.843 1.00 41.51  ? 446 ARG A NE  1 
ATOM   3344  C  CZ  . ARG A 1 446 ? 255.212 277.716 260.711 1.00 41.88  ? 446 ARG A CZ  1 
ATOM   3345  N  NH1 . ARG A 1 446 ? 254.275 276.801 260.901 1.00 40.62  ? 446 ARG A NH1 1 
ATOM   3346  N  NH2 . ARG A 1 446 ? 256.343 277.642 261.406 1.00 45.76  ? 446 ARG A NH2 1 
ATOM   3347  N  N   . PHE A 1 447 ? 252.281 276.886 255.350 1.00 32.53  ? 447 PHE A N   1 
ATOM   3348  C  CA  . PHE A 1 447 ? 252.392 275.438 255.453 1.00 27.03  ? 447 PHE A CA  1 
ATOM   3349  C  C   . PHE A 1 447 ? 252.629 274.752 254.116 1.00 26.57  ? 447 PHE A C   1 
ATOM   3350  O  O   . PHE A 1 447 ? 253.022 273.581 254.106 1.00 27.58  ? 447 PHE A O   1 
ATOM   3351  C  CB  . PHE A 1 447 ? 251.141 274.864 256.117 1.00 21.55  ? 447 PHE A CB  1 
ATOM   3352  C  CG  . PHE A 1 447 ? 251.056 275.156 257.584 1.00 24.95  ? 447 PHE A CG  1 
ATOM   3353  C  CD1 . PHE A 1 447 ? 251.737 274.372 258.497 1.00 29.21  ? 447 PHE A CD1 1 
ATOM   3354  C  CD2 . PHE A 1 447 ? 250.301 276.216 258.049 1.00 28.99  ? 447 PHE A CD2 1 
ATOM   3355  C  CE1 . PHE A 1 447 ? 251.665 274.639 259.846 1.00 27.51  ? 447 PHE A CE1 1 
ATOM   3356  C  CE2 . PHE A 1 447 ? 250.225 276.488 259.400 1.00 28.03  ? 447 PHE A CE2 1 
ATOM   3357  C  CZ  . PHE A 1 447 ? 250.909 275.698 260.299 1.00 27.87  ? 447 PHE A CZ  1 
ATOM   3358  N  N   . ILE A 1 448 ? 252.413 275.440 252.990 1.00 24.79  ? 448 ILE A N   1 
ATOM   3359  C  CA  . ILE A 1 448 ? 252.788 274.887 251.694 1.00 23.42  ? 448 ILE A CA  1 
ATOM   3360  C  C   . ILE A 1 448 ? 254.239 275.184 251.350 1.00 26.77  ? 448 ILE A C   1 
ATOM   3361  O  O   . ILE A 1 448 ? 254.703 274.800 250.268 1.00 32.25  ? 448 ILE A O   1 
ATOM   3362  C  CB  . ILE A 1 448 ? 251.858 275.399 250.575 1.00 28.39  ? 448 ILE A CB  1 
ATOM   3363  C  CG1 . ILE A 1 448 ? 252.185 276.849 250.219 1.00 26.44  ? 448 ILE A CG1 1 
ATOM   3364  C  CG2 . ILE A 1 448 ? 250.403 275.259 250.989 1.00 25.51  ? 448 ILE A CG2 1 
ATOM   3365  C  CD1 . ILE A 1 448 ? 251.747 277.243 248.828 1.00 22.84  ? 448 ILE A CD1 1 
ATOM   3366  N  N   . ARG A 1 449 ? 254.968 275.859 252.235 1.00 27.15  ? 449 ARG A N   1 
ATOM   3367  C  CA  . ARG A 1 449 ? 256.404 276.020 252.065 1.00 24.85  ? 449 ARG A CA  1 
ATOM   3368  C  C   . ARG A 1 449 ? 257.096 274.669 252.179 1.00 32.01  ? 449 ARG A C   1 
ATOM   3369  O  O   . ARG A 1 449 ? 256.757 273.850 253.037 1.00 35.69  ? 449 ARG A O   1 
ATOM   3370  C  CB  . ARG A 1 449 ? 256.955 276.986 253.112 1.00 28.71  ? 449 ARG A CB  1 
ATOM   3371  C  CG  . ARG A 1 449 ? 257.296 278.361 252.573 1.00 31.62  ? 449 ARG A CG  1 
ATOM   3372  C  CD  . ARG A 1 449 ? 257.363 279.384 253.692 1.00 36.93  ? 449 ARG A CD  1 
ATOM   3373  N  NE  . ARG A 1 449 ? 256.324 280.397 253.561 1.00 44.15  ? 449 ARG A NE  1 
ATOM   3374  C  CZ  . ARG A 1 449 ? 256.013 281.281 254.499 1.00 46.96  ? 449 ARG A CZ  1 
ATOM   3375  N  NH1 . ARG A 1 449 ? 256.642 281.303 255.663 1.00 47.11  ? 449 ARG A NH1 1 
ATOM   3376  N  NH2 . ARG A 1 449 ? 255.047 282.163 254.265 1.00 40.20  ? 449 ARG A NH2 1 
ATOM   3377  N  N   . SER A 1 450 ? 258.078 274.437 251.307 1.00 29.20  ? 450 SER A N   1 
ATOM   3378  C  CA  . SER A 1 450 ? 258.721 273.131 251.248 1.00 24.19  ? 450 SER A CA  1 
ATOM   3379  C  C   . SER A 1 450 ? 259.524 272.802 252.498 1.00 29.07  ? 450 SER A C   1 
ATOM   3380  O  O   . SER A 1 450 ? 259.917 271.644 252.668 1.00 32.63  ? 450 SER A O   1 
ATOM   3381  C  CB  . SER A 1 450 ? 259.625 273.047 250.018 1.00 27.18  ? 450 SER A CB  1 
ATOM   3382  O  OG  . SER A 1 450 ? 258.866 273.124 248.825 1.00 27.53  ? 450 SER A OG  1 
ATOM   3383  N  N   . ALA A 1 451 ? 259.779 273.776 253.373 1.00 31.03  ? 451 ALA A N   1 
ATOM   3384  C  CA  . ALA A 1 451 ? 260.547 273.527 254.584 1.00 27.90  ? 451 ALA A CA  1 
ATOM   3385  C  C   . ALA A 1 451 ? 259.683 273.274 255.812 1.00 31.53  ? 451 ALA A C   1 
ATOM   3386  O  O   . ALA A 1 451 ? 260.193 272.750 256.807 1.00 33.15  ? 451 ALA A O   1 
ATOM   3387  C  CB  . ALA A 1 451 ? 261.487 274.703 254.870 1.00 30.20  ? 451 ALA A CB  1 
ATOM   3388  N  N   . THR A 1 452 ? 258.403 273.632 255.771 1.00 30.28  ? 452 THR A N   1 
ATOM   3389  C  CA  . THR A 1 452 ? 257.530 273.414 256.915 1.00 27.09  ? 452 THR A CA  1 
ATOM   3390  C  C   . THR A 1 452 ? 257.245 271.928 257.101 1.00 33.57  ? 452 THR A C   1 
ATOM   3391  O  O   . THR A 1 452 ? 256.961 271.207 256.141 1.00 35.19  ? 452 THR A O   1 
ATOM   3392  C  CB  . THR A 1 452 ? 256.219 274.180 256.741 1.00 31.68  ? 452 THR A CB  1 
ATOM   3393  O  OG1 . THR A 1 452 ? 256.501 275.526 256.340 1.00 35.13  ? 452 THR A OG1 1 
ATOM   3394  C  CG2 . THR A 1 452 ? 255.436 274.201 258.043 1.00 29.59  ? 452 THR A CG2 1 
ATOM   3395  N  N   . ARG A 1 453 ? 257.319 271.475 258.348 1.00 32.94  ? 453 ARG A N   1 
ATOM   3396  C  CA  . ARG A 1 453 ? 257.056 270.089 258.709 1.00 28.02  ? 453 ARG A CA  1 
ATOM   3397  C  C   . ARG A 1 453 ? 255.748 270.005 259.480 1.00 31.12  ? 453 ARG A C   1 
ATOM   3398  O  O   . ARG A 1 453 ? 255.535 270.770 260.426 1.00 37.59  ? 453 ARG A O   1 
ATOM   3399  C  CB  . ARG A 1 453 ? 258.191 269.521 259.563 1.00 27.06  ? 453 ARG A CB  1 
ATOM   3400  C  CG  . ARG A 1 453 ? 259.588 269.837 259.066 1.00 32.11  ? 453 ARG A CG  1 
ATOM   3401  C  CD  . ARG A 1 453 ? 260.615 269.614 260.163 1.00 31.35  ? 453 ARG A CD  1 
ATOM   3402  N  NE  . ARG A 1 453 ? 260.893 268.201 260.390 1.00 33.73  ? 453 ARG A NE  1 
ATOM   3403  C  CZ  . ARG A 1 453 ? 261.007 267.645 261.589 1.00 32.73  ? 453 ARG A CZ  1 
ATOM   3404  N  NH1 . ARG A 1 453 ? 260.865 268.355 262.696 1.00 27.86  ? 453 ARG A NH1 1 
ATOM   3405  N  NH2 . ARG A 1 453 ? 261.270 266.345 261.679 1.00 30.70  ? 453 ARG A NH2 1 
ATOM   3406  N  N   . SER A 1 454 ? 254.875 269.082 259.086 1.00 28.70  ? 454 SER A N   1 
ATOM   3407  C  CA  . SER A 1 454 ? 253.703 268.742 259.872 1.00 29.26  ? 454 SER A CA  1 
ATOM   3408  C  C   . SER A 1 454 ? 253.840 267.299 260.338 1.00 29.81  ? 454 SER A C   1 
ATOM   3409  O  O   . SER A 1 454 ? 254.798 266.605 260.000 1.00 27.66  ? 454 SER A O   1 
ATOM   3410  C  CB  . SER A 1 454 ? 252.425 268.951 259.059 1.00 27.73  ? 454 SER A CB  1 
ATOM   3411  O  OG  . SER A 1 454 ? 251.873 270.231 259.305 1.00 41.92  ? 454 SER A OG  1 
ATOM   3412  N  N   . HIS A 1 455 ? 252.859 266.831 261.102 1.00 26.20  ? 455 HIS A N   1 
ATOM   3413  C  CA  . HIS A 1 455 ? 252.892 265.449 261.548 1.00 26.60  ? 455 HIS A CA  1 
ATOM   3414  C  C   . HIS A 1 455 ? 251.471 264.936 261.702 1.00 28.46  ? 455 HIS A C   1 
ATOM   3415  O  O   . HIS A 1 455 ? 250.524 265.706 261.878 1.00 29.63  ? 455 HIS A O   1 
ATOM   3416  C  CB  . HIS A 1 455 ? 253.662 265.296 262.864 1.00 27.21  ? 455 HIS A CB  1 
ATOM   3417  C  CG  . HIS A 1 455 ? 253.369 266.371 263.863 1.00 28.45  ? 455 HIS A CG  1 
ATOM   3418  N  ND1 . HIS A 1 455 ? 252.520 266.181 264.931 1.00 33.71  ? 455 HIS A ND1 1 
ATOM   3419  C  CD2 . HIS A 1 455 ? 253.812 267.646 263.956 1.00 29.47  ? 455 HIS A CD2 1 
ATOM   3420  C  CE1 . HIS A 1 455 ? 252.452 267.294 265.639 1.00 35.51  ? 455 HIS A CE1 1 
ATOM   3421  N  NE2 . HIS A 1 455 ? 253.226 268.198 265.069 1.00 36.74  ? 455 HIS A NE2 1 
ATOM   3422  N  N   . GLU A 1 456 ? 251.337 263.616 261.630 1.00 24.32  ? 456 GLU A N   1 
ATOM   3423  C  CA  . GLU A 1 456 ? 250.046 262.978 261.835 1.00 21.18  ? 456 GLU A CA  1 
ATOM   3424  C  C   . GLU A 1 456 ? 250.266 261.582 262.394 1.00 22.60  ? 456 GLU A C   1 
ATOM   3425  O  O   . GLU A 1 456 ? 251.300 260.959 262.152 1.00 25.81  ? 456 GLU A O   1 
ATOM   3426  C  CB  . GLU A 1 456 ? 249.235 262.917 260.535 1.00 22.02  ? 456 GLU A CB  1 
ATOM   3427  C  CG  . GLU A 1 456 ? 247.805 262.441 260.719 1.00 21.96  ? 456 GLU A CG  1 
ATOM   3428  C  CD  . GLU A 1 456 ? 247.050 263.256 261.748 1.00 30.60  ? 456 GLU A CD  1 
ATOM   3429  O  OE1 . GLU A 1 456 ? 246.532 264.335 261.394 1.00 35.05  ? 456 GLU A OE1 1 
ATOM   3430  O  OE2 . GLU A 1 456 ? 246.975 262.818 262.915 1.00 33.92  ? 456 GLU A OE2 1 
ATOM   3431  N  N   . TYR A 1 457 ? 249.283 261.097 263.143 1.00 24.84  ? 457 TYR A N   1 
ATOM   3432  C  CA  . TYR A 1 457 ? 249.371 259.754 263.697 1.00 20.23  ? 457 TYR A CA  1 
ATOM   3433  C  C   . TYR A 1 457 ? 249.248 258.716 262.590 1.00 21.69  ? 457 TYR A C   1 
ATOM   3434  O  O   . TYR A 1 457 ? 248.483 258.884 261.638 1.00 24.63  ? 457 TYR A O   1 
ATOM   3435  C  CB  . TYR A 1 457 ? 248.294 259.547 264.757 1.00 24.47  ? 457 TYR A CB  1 
ATOM   3436  C  CG  . TYR A 1 457 ? 248.543 260.342 266.016 1.00 26.21  ? 457 TYR A CG  1 
ATOM   3437  C  CD1 . TYR A 1 457 ? 249.532 259.963 266.911 1.00 25.58  ? 457 TYR A CD1 1 
ATOM   3438  C  CD2 . TYR A 1 457 ? 247.800 261.477 266.303 1.00 25.64  ? 457 TYR A CD2 1 
ATOM   3439  C  CE1 . TYR A 1 457 ? 249.767 260.687 268.062 1.00 28.93  ? 457 TYR A CE1 1 
ATOM   3440  C  CE2 . TYR A 1 457 ? 248.028 262.207 267.448 1.00 24.00  ? 457 TYR A CE2 1 
ATOM   3441  C  CZ  . TYR A 1 457 ? 249.013 261.809 268.324 1.00 30.02  ? 457 TYR A CZ  1 
ATOM   3442  O  OH  . TYR A 1 457 ? 249.239 262.537 269.468 1.00 36.01  ? 457 TYR A OH  1 
ATOM   3443  N  N   . GLN A 1 458 ? 250.010 257.631 262.726 1.00 21.43  ? 458 GLN A N   1 
ATOM   3444  C  CA  . GLN A 1 458 ? 250.180 256.670 261.644 1.00 19.95  ? 458 GLN A CA  1 
ATOM   3445  C  C   . GLN A 1 458 ? 248.900 255.928 261.284 1.00 20.15  ? 458 GLN A C   1 
ATOM   3446  O  O   . GLN A 1 458 ? 248.863 255.282 260.233 1.00 22.54  ? 458 GLN A O   1 
ATOM   3447  C  CB  . GLN A 1 458 ? 251.269 255.663 262.012 1.00 20.06  ? 458 GLN A CB  1 
ATOM   3448  C  CG  . GLN A 1 458 ? 251.018 254.923 263.310 1.00 20.98  ? 458 GLN A CG  1 
ATOM   3449  C  CD  . GLN A 1 458 ? 251.986 253.781 263.519 1.00 26.40  ? 458 GLN A CD  1 
ATOM   3450  O  OE1 . GLN A 1 458 ? 253.200 253.976 263.526 1.00 28.67  ? 458 GLN A OE1 1 
ATOM   3451  N  NE2 . GLN A 1 458 ? 251.455 252.579 263.685 1.00 30.96  ? 458 GLN A NE2 1 
ATOM   3452  N  N   . ASN A 1 459 ? 247.867 255.983 262.121 1.00 22.42  ? 459 ASN A N   1 
ATOM   3453  C  CA  . ASN A 1 459 ? 246.614 255.291 261.849 1.00 21.30  ? 459 ASN A CA  1 
ATOM   3454  C  C   . ASN A 1 459 ? 245.478 256.245 261.504 1.00 21.73  ? 459 ASN A C   1 
ATOM   3455  O  O   . ASN A 1 459 ? 244.319 255.821 261.461 1.00 26.32  ? 459 ASN A O   1 
ATOM   3456  C  CB  . ASN A 1 459 ? 246.221 254.416 263.042 1.00 20.90  ? 459 ASN A CB  1 
ATOM   3457  C  CG  . ASN A 1 459 ? 246.020 255.214 264.316 1.00 23.83  ? 459 ASN A CG  1 
ATOM   3458  O  OD1 . ASN A 1 459 ? 246.566 256.305 264.475 1.00 28.63  ? 459 ASN A OD1 1 
ATOM   3459  N  ND2 . ASN A 1 459 ? 245.236 254.667 265.236 1.00 22.75  ? 459 ASN A ND2 1 
ATOM   3460  N  N   . VAL A 1 460 ? 245.778 257.515 261.248 1.00 20.33  ? 460 VAL A N   1 
ATOM   3461  C  CA  . VAL A 1 460 ? 244.768 258.538 261.012 1.00 20.67  ? 460 VAL A CA  1 
ATOM   3462  C  C   . VAL A 1 460 ? 244.792 258.927 259.542 1.00 23.71  ? 460 VAL A C   1 
ATOM   3463  O  O   . VAL A 1 460 ? 245.845 259.289 259.004 1.00 28.65  ? 460 VAL A O   1 
ATOM   3464  C  CB  . VAL A 1 460 ? 244.995 259.770 261.907 1.00 22.73  ? 460 VAL A CB  1 
ATOM   3465  C  CG1 . VAL A 1 460 ? 243.981 260.851 261.586 1.00 23.02  ? 460 VAL A CG1 1 
ATOM   3466  C  CG2 . VAL A 1 460 ? 244.920 259.381 263.371 1.00 23.43  ? 460 VAL A CG2 1 
ATOM   3467  N  N   . GLY A 1 461 ? 243.634 258.851 258.895 1.00 23.14  ? 461 GLY A N   1 
ATOM   3468  C  CA  . GLY A 1 461 ? 243.460 259.357 257.549 1.00 19.67  ? 461 GLY A CA  1 
ATOM   3469  C  C   . GLY A 1 461 ? 242.754 260.700 257.571 1.00 24.18  ? 461 GLY A C   1 
ATOM   3470  O  O   . GLY A 1 461 ? 241.897 260.953 258.414 1.00 26.95  ? 461 GLY A O   1 
ATOM   3471  N  N   . ARG A 1 462 ? 243.125 261.565 256.631 1.00 22.84  ? 462 ARG A N   1 
ATOM   3472  C  CA  . ARG A 1 462 ? 242.594 262.918 256.564 1.00 21.79  ? 462 ARG A CA  1 
ATOM   3473  C  C   . ARG A 1 462 ? 242.180 263.241 255.138 1.00 22.20  ? 462 ARG A C   1 
ATOM   3474  O  O   . ARG A 1 462 ? 242.724 262.689 254.178 1.00 27.24  ? 462 ARG A O   1 
ATOM   3475  C  CB  . ARG A 1 462 ? 243.620 263.950 257.045 1.00 19.54  ? 462 ARG A CB  1 
ATOM   3476  C  CG  . ARG A 1 462 ? 243.988 263.814 258.504 1.00 23.45  ? 462 ARG A CG  1 
ATOM   3477  C  CD  . ARG A 1 462 ? 243.011 264.547 259.394 1.00 23.19  ? 462 ARG A CD  1 
ATOM   3478  N  NE  . ARG A 1 462 ? 243.463 264.549 260.779 1.00 26.58  ? 462 ARG A NE  1 
ATOM   3479  C  CZ  . ARG A 1 462 ? 242.765 265.041 261.792 1.00 32.35  ? 462 ARG A CZ  1 
ATOM   3480  N  NH1 . ARG A 1 462 ? 241.573 265.583 261.611 1.00 38.51  ? 462 ARG A NH1 1 
ATOM   3481  N  NH2 . ARG A 1 462 ? 243.277 264.988 263.018 1.00 34.36  ? 462 ARG A NH2 1 
ATOM   3482  N  N   . SER A 1 463 ? 241.215 264.150 255.007 1.00 21.78  ? 463 SER A N   1 
ATOM   3483  C  CA  . SER A 1 463 ? 240.754 264.575 253.692 1.00 20.55  ? 463 SER A CA  1 
ATOM   3484  C  C   . SER A 1 463 ? 241.736 265.502 252.994 1.00 19.31  ? 463 SER A C   1 
ATOM   3485  O  O   . SER A 1 463 ? 241.430 265.992 251.903 1.00 20.22  ? 463 SER A O   1 
ATOM   3486  C  CB  . SER A 1 463 ? 239.392 265.261 253.807 1.00 18.79  ? 463 SER A CB  1 
ATOM   3487  O  OG  . SER A 1 463 ? 239.374 266.185 254.878 1.00 21.82  ? 463 SER A OG  1 
ATOM   3488  N  N   . TYR A 1 464 ? 242.902 265.753 253.590 1.00 20.22  ? 464 TYR A N   1 
ATOM   3489  C  CA  . TYR A 1 464 ? 243.898 266.630 252.993 1.00 18.18  ? 464 TYR A CA  1 
ATOM   3490  C  C   . TYR A 1 464 ? 245.289 266.009 252.959 1.00 17.72  ? 464 TYR A C   1 
ATOM   3491  O  O   . TYR A 1 464 ? 246.257 266.716 252.662 1.00 20.27  ? 464 TYR A O   1 
ATOM   3492  C  CB  . TYR A 1 464 ? 243.949 267.969 253.734 1.00 17.94  ? 464 TYR A CB  1 
ATOM   3493  C  CG  . TYR A 1 464 ? 244.013 267.845 255.237 1.00 18.41  ? 464 TYR A CG  1 
ATOM   3494  C  CD1 . TYR A 1 464 ? 245.231 267.750 255.895 1.00 16.13  ? 464 TYR A CD1 1 
ATOM   3495  C  CD2 . TYR A 1 464 ? 242.854 267.837 255.999 1.00 20.11  ? 464 TYR A CD2 1 
ATOM   3496  C  CE1 . TYR A 1 464 ? 245.291 267.642 257.266 1.00 16.80  ? 464 TYR A CE1 1 
ATOM   3497  C  CE2 . TYR A 1 464 ? 242.906 267.732 257.370 1.00 21.04  ? 464 TYR A CE2 1 
ATOM   3498  C  CZ  . TYR A 1 464 ? 244.126 267.638 257.999 1.00 23.64  ? 464 TYR A CZ  1 
ATOM   3499  O  OH  . TYR A 1 464 ? 244.179 267.533 259.366 1.00 33.27  ? 464 TYR A OH  1 
ATOM   3500  N  N   . ILE A 1 465 ? 245.419 264.718 253.245 1.00 15.78  ? 465 ILE A N   1 
ATOM   3501  C  CA  . ILE A 1 465 ? 246.707 264.036 253.226 1.00 17.37  ? 465 ILE A CA  1 
ATOM   3502  C  C   . ILE A 1 465 ? 246.642 262.916 252.198 1.00 19.69  ? 465 ILE A C   1 
ATOM   3503  O  O   . ILE A 1 465 ? 245.837 261.986 252.331 1.00 23.01  ? 465 ILE A O   1 
ATOM   3504  C  CB  . ILE A 1 465 ? 247.086 263.490 254.612 1.00 19.54  ? 465 ILE A CB  1 
ATOM   3505  C  CG1 . ILE A 1 465 ? 247.039 264.606 255.656 1.00 17.70  ? 465 ILE A CG1 1 
ATOM   3506  C  CG2 . ILE A 1 465 ? 248.469 262.857 254.575 1.00 13.17  ? 465 ILE A CG2 1 
ATOM   3507  C  CD1 . ILE A 1 465 ? 247.441 264.165 257.042 1.00 14.70  ? 465 ILE A CD1 1 
ATOM   3508  N  N   . GLY A 1 466 ? 247.486 263.009 251.176 1.00 18.50  ? 466 GLY A N   1 
ATOM   3509  C  CA  . GLY A 1 466 ? 247.680 261.936 250.224 1.00 17.42  ? 466 GLY A CA  1 
ATOM   3510  C  C   . GLY A 1 466 ? 249.094 261.405 250.316 1.00 18.32  ? 466 GLY A C   1 
ATOM   3511  O  O   . GLY A 1 466 ? 249.694 261.433 251.394 1.00 20.75  ? 466 GLY A O   1 
ATOM   3512  N  N   . PHE A 1 467 ? 249.647 260.927 249.206 1.00 22.42  ? 467 PHE A N   1 
ATOM   3513  C  CA  . PHE A 1 467 ? 251.018 260.438 249.220 1.00 19.37  ? 467 PHE A CA  1 
ATOM   3514  C  C   . PHE A 1 467 ? 251.440 260.097 247.801 1.00 19.28  ? 467 PHE A C   1 
ATOM   3515  O  O   . PHE A 1 467 ? 250.605 259.895 246.916 1.00 24.40  ? 467 PHE A O   1 
ATOM   3516  C  CB  . PHE A 1 467 ? 251.171 259.214 250.131 1.00 18.10  ? 467 PHE A CB  1 
ATOM   3517  C  CG  . PHE A 1 467 ? 250.567 257.959 249.569 1.00 18.71  ? 467 PHE A CG  1 
ATOM   3518  C  CD1 . PHE A 1 467 ? 249.198 257.761 249.591 1.00 15.83  ? 467 PHE A CD1 1 
ATOM   3519  C  CD2 . PHE A 1 467 ? 251.371 256.976 249.018 1.00 20.74  ? 467 PHE A CD2 1 
ATOM   3520  C  CE1 . PHE A 1 467 ? 248.643 256.610 249.075 1.00 14.26  ? 467 PHE A CE1 1 
ATOM   3521  C  CE2 . PHE A 1 467 ? 250.822 255.824 248.499 1.00 17.25  ? 467 PHE A CE2 1 
ATOM   3522  C  CZ  . PHE A 1 467 ? 249.456 255.640 248.528 1.00 16.39  ? 467 PHE A CZ  1 
ATOM   3523  N  N   . ARG A 1 468 ? 252.754 260.045 247.599 1.00 20.77  ? 468 ARG A N   1 
ATOM   3524  C  CA  . ARG A 1 468 ? 253.344 259.535 246.372 1.00 22.08  ? 468 ARG A CA  1 
ATOM   3525  C  C   . ARG A 1 468 ? 254.519 258.642 246.742 1.00 24.23  ? 468 ARG A C   1 
ATOM   3526  O  O   . ARG A 1 468 ? 255.067 258.730 247.843 1.00 25.37  ? 468 ARG A O   1 
ATOM   3527  C  CB  . ARG A 1 468 ? 253.796 260.662 245.433 1.00 19.80  ? 468 ARG A CB  1 
ATOM   3528  C  CG  . ARG A 1 468 ? 254.970 261.474 245.942 1.00 20.79  ? 468 ARG A CG  1 
ATOM   3529  C  CD  . ARG A 1 468 ? 255.291 262.612 244.993 1.00 22.67  ? 468 ARG A CD  1 
ATOM   3530  N  NE  . ARG A 1 468 ? 254.387 263.741 245.170 1.00 24.68  ? 468 ARG A NE  1 
ATOM   3531  C  CZ  . ARG A 1 468 ? 254.058 264.593 244.210 1.00 23.43  ? 468 ARG A CZ  1 
ATOM   3532  N  NH1 . ARG A 1 468 ? 254.542 264.476 242.986 1.00 19.74  ? 468 ARG A NH1 1 
ATOM   3533  N  NH2 . ARG A 1 468 ? 253.223 265.589 244.487 1.00 19.73  ? 468 ARG A NH2 1 
ATOM   3534  N  N   . CYS A 1 469 ? 254.897 257.774 245.813 1.00 23.69  ? 469 CYS A N   1 
ATOM   3535  C  CA  . CYS A 1 469 ? 255.929 256.780 246.057 1.00 19.75  ? 469 CYS A CA  1 
ATOM   3536  C  C   . CYS A 1 469 ? 257.266 257.212 245.466 1.00 18.76  ? 469 CYS A C   1 
ATOM   3537  O  O   . CYS A 1 469 ? 257.335 258.016 244.534 1.00 23.56  ? 469 CYS A O   1 
ATOM   3538  C  CB  . CYS A 1 469 ? 255.521 255.424 245.476 1.00 22.84  ? 469 CYS A CB  1 
ATOM   3539  S  SG  . CYS A 1 469 ? 253.909 254.829 246.028 1.00 41.56  ? 469 CYS A SG  1 
ATOM   3540  N  N   . VAL A 1 470 ? 258.337 256.660 246.034 1.00 19.21  ? 470 VAL A N   1 
ATOM   3541  C  CA  . VAL A 1 470 ? 259.682 256.814 245.505 1.00 20.05  ? 470 VAL A CA  1 
ATOM   3542  C  C   . VAL A 1 470 ? 260.317 255.434 245.416 1.00 21.89  ? 470 VAL A C   1 
ATOM   3543  O  O   . VAL A 1 470 ? 259.880 254.477 246.058 1.00 24.69  ? 470 VAL A O   1 
ATOM   3544  C  CB  . VAL A 1 470 ? 260.560 257.756 246.360 1.00 21.87  ? 470 VAL A CB  1 
ATOM   3545  C  CG1 . VAL A 1 470 ? 260.064 259.188 246.257 1.00 20.41  ? 470 VAL A CG1 1 
ATOM   3546  C  CG2 . VAL A 1 470 ? 260.589 257.293 247.806 1.00 19.14  ? 470 VAL A CG2 1 
ATOM   3547  N  N   . ARG A 1 471 ? 261.360 255.343 244.600 1.00 25.42  ? 471 ARG A N   1 
ATOM   3548  C  CA  . ARG A 1 471 ? 262.085 254.089 244.428 1.00 29.27  ? 471 ARG A CA  1 
ATOM   3549  C  C   . ARG A 1 471 ? 263.553 254.405 244.204 1.00 29.51  ? 471 ARG A C   1 
ATOM   3550  O  O   . ARG A 1 471 ? 263.891 255.134 243.270 1.00 31.88  ? 471 ARG A O   1 
ATOM   3551  C  CB  . ARG A 1 471 ? 261.521 253.279 243.259 1.00 29.17  ? 471 ARG A CB  1 
ATOM   3552  C  CG  . ARG A 1 471 ? 262.348 252.058 242.907 1.00 36.90  ? 471 ARG A CG  1 
ATOM   3553  C  CD  . ARG A 1 471 ? 261.471 250.911 242.442 1.00 38.58  ? 471 ARG A CD  1 
ATOM   3554  N  NE  . ARG A 1 471 ? 261.448 250.795 240.989 1.00 46.46  ? 471 ARG A NE  1 
ATOM   3555  C  CZ  . ARG A 1 471 ? 262.475 250.394 240.252 1.00 61.67  ? 471 ARG A CZ  1 
ATOM   3556  N  NH1 . ARG A 1 471 ? 263.631 250.062 240.801 1.00 63.53  ? 471 ARG A NH1 1 
ATOM   3557  N  NH2 . ARG A 1 471 ? 262.337 250.323 238.932 1.00 69.54  ? 471 ARG A NH2 1 
ATOM   3558  N  N   . THR A 1 472 ? 264.421 253.871 245.057 1.00 34.94  ? 472 THR A N   1 
ATOM   3559  C  CA  . THR A 1 472 ? 265.850 254.086 244.878 1.00 32.81  ? 472 THR A CA  1 
ATOM   3560  C  C   . THR A 1 472 ? 266.286 253.562 243.518 1.00 36.17  ? 472 THR A C   1 
ATOM   3561  O  O   . THR A 1 472 ? 265.942 252.442 243.128 1.00 35.82  ? 472 THR A O   1 
ATOM   3562  C  CB  . THR A 1 472 ? 266.639 253.399 245.992 1.00 34.32  ? 472 THR A CB  1 
ATOM   3563  O  OG1 . THR A 1 472 ? 266.633 254.226 247.161 1.00 39.56  ? 472 THR A OG1 1 
ATOM   3564  C  CG2 . THR A 1 472 ? 268.076 253.167 245.557 1.00 32.51  ? 472 THR A CG2 1 
ATOM   3565  N  N   . SER A 1 473 ? 267.044 254.377 242.795 1.00 38.60  ? 473 SER A N   1 
ATOM   3566  C  CA  . SER A 1 473 ? 267.463 254.067 241.438 1.00 44.61  ? 473 SER A CA  1 
ATOM   3567  C  C   . SER A 1 473 ? 268.940 253.700 241.419 1.00 53.01  ? 473 SER A C   1 
ATOM   3568  O  O   . SER A 1 473 ? 269.763 254.362 242.060 1.00 53.29  ? 473 SER A O   1 
ATOM   3569  C  CB  . SER A 1 473 ? 267.206 255.253 240.504 1.00 38.38  ? 473 SER A CB  1 
ATOM   3570  O  OG  . SER A 1 473 ? 268.071 256.332 240.803 1.00 40.64  ? 473 SER A OG  1 
ATOM   3571  N  N   . ILE A 1 474 ? 269.269 252.641 240.685 1.00 56.55  ? 474 ILE A N   1 
ATOM   3572  C  CA  . ILE A 1 474 ? 270.649 252.192 240.537 1.00 60.68  ? 474 ILE A CA  1 
ATOM   3573  C  C   . ILE A 1 474 ? 271.216 252.910 239.317 1.00 57.50  ? 474 ILE A C   1 
ATOM   3574  O  O   . ILE A 1 474 ? 270.975 252.514 238.176 1.00 58.89  ? 474 ILE A O   1 
ATOM   3575  C  CB  . ILE A 1 474 ? 270.742 250.671 240.399 1.00 66.31  ? 474 ILE A CB  1 
ATOM   3576  C  CG1 . ILE A 1 474 ? 269.455 250.006 240.894 1.00 61.25  ? 474 ILE A CG1 1 
ATOM   3577  C  CG2 . ILE A 1 474 ? 271.937 250.142 241.178 1.00 56.33  ? 474 ILE A CG2 1 
ATOM   3578  C  CD1 . ILE A 1 474 ? 269.220 250.144 242.382 1.00 54.28  ? 474 ILE A CD1 1 
ATOM   3579  N  N   . ALA A 1 475 ? 271.977 253.974 239.562 1.00 58.85  ? 475 ALA A N   1 
ATOM   3580  C  CA  . ALA A 1 475 ? 272.528 254.809 238.507 1.00 57.19  ? 475 ALA A CA  1 
ATOM   3581  C  C   . ALA A 1 475 ? 274.008 255.046 238.765 1.00 58.65  ? 475 ALA A C   1 
ATOM   3582  O  O   . ALA A 1 475 ? 274.469 255.013 239.909 1.00 58.06  ? 475 ALA A O   1 
ATOM   3583  C  CB  . ALA A 1 475 ? 271.791 256.152 238.410 1.00 49.59  ? 475 ALA A CB  1 
ATOM   3584  N  N   . PHE A 1 476 ? 274.748 255.286 237.688 1.00 59.35  ? 476 PHE A N   1 
ATOM   3585  C  CA  . PHE A 1 476 ? 276.193 255.456 237.783 1.00 55.42  ? 476 PHE A CA  1 
ATOM   3586  C  C   . PHE A 1 476 ? 276.657 256.719 237.064 1.00 52.99  ? 476 PHE A C   1 
ATOM   3587  O  O   . PHE A 1 476 ? 277.301 257.583 237.660 1.00 51.61  ? 476 PHE A O   1 
ATOM   3588  C  CB  . PHE A 1 476 ? 276.905 254.228 237.214 1.00 45.94  ? 476 PHE A CB  1 
ATOM   3589  C  CG  . PHE A 1 476 ? 276.312 252.925 237.667 1.00 50.85  ? 476 PHE A CG  1 
ATOM   3590  C  CD1 . PHE A 1 476 ? 276.760 252.309 238.822 1.00 45.60  ? 476 PHE A CD1 1 
ATOM   3591  C  CD2 . PHE A 1 476 ? 275.300 252.320 236.941 1.00 50.92  ? 476 PHE A CD2 1 
ATOM   3592  C  CE1 . PHE A 1 476 ? 276.211 251.116 239.244 1.00 42.36  ? 476 PHE A CE1 1 
ATOM   3593  C  CE2 . PHE A 1 476 ? 274.749 251.126 237.358 1.00 49.32  ? 476 PHE A CE2 1 
ATOM   3594  C  CZ  . PHE A 1 476 ? 275.204 250.524 238.511 1.00 47.10  ? 476 PHE A CZ  1 
ATOM   3595  N  N   . THR B 2 49  ? 259.365 250.224 281.792 1.00 50.19  ? 47  THR B N   1 
ATOM   3596  C  CA  . THR B 2 49  ? 258.108 250.645 281.186 1.00 55.84  ? 47  THR B CA  1 
ATOM   3597  C  C   . THR B 2 49  ? 258.266 250.845 279.682 1.00 56.64  ? 47  THR B C   1 
ATOM   3598  O  O   . THR B 2 49  ? 257.299 250.740 278.928 1.00 57.50  ? 47  THR B O   1 
ATOM   3599  C  CB  . THR B 2 49  ? 257.598 251.941 281.842 1.00 30.00  ? 47  THR B CB  1 
ATOM   3600  O  OG1 . THR B 2 49  ? 258.577 252.974 281.690 1.00 30.00  ? 47  THR B OG1 1 
ATOM   3601  C  CG2 . THR B 2 49  ? 257.498 251.772 283.351 1.00 30.00  ? 47  THR B CG2 1 
ATOM   3602  N  N   . LEU B 2 50  ? 259.489 251.139 279.252 1.00 48.92  ? 48  LEU B N   1 
ATOM   3603  C  CA  . LEU B 2 50  ? 259.769 251.301 277.834 1.00 44.29  ? 48  LEU B CA  1 
ATOM   3604  C  C   . LEU B 2 50  ? 259.711 249.960 277.113 1.00 45.81  ? 48  LEU B C   1 
ATOM   3605  O  O   . LEU B 2 50  ? 259.987 248.904 277.689 1.00 49.79  ? 48  LEU B O   1 
ATOM   3606  C  CB  . LEU B 2 50  ? 261.142 251.939 277.628 1.00 44.93  ? 48  LEU B CB  1 
ATOM   3607  C  CG  . LEU B 2 50  ? 261.165 253.358 277.062 1.00 46.56  ? 48  LEU B CG  1 
ATOM   3608  C  CD1 . LEU B 2 50  ? 260.361 254.299 277.942 1.00 45.85  ? 48  LEU B CD1 1 
ATOM   3609  C  CD2 . LEU B 2 50  ? 262.596 253.847 276.913 1.00 42.74  ? 48  LEU B CD2 1 
ATOM   3610  N  N   . SER B 2 51  ? 259.344 250.010 275.837 1.00 41.93  ? 49  SER B N   1 
ATOM   3611  C  CA  . SER B 2 51  ? 259.334 248.826 274.994 1.00 34.67  ? 49  SER B CA  1 
ATOM   3612  C  C   . SER B 2 51  ? 260.714 248.602 274.387 1.00 36.21  ? 49  SER B C   1 
ATOM   3613  O  O   . SER B 2 51  ? 261.546 249.509 274.320 1.00 38.49  ? 49  SER B O   1 
ATOM   3614  C  CB  . SER B 2 51  ? 258.288 248.958 273.887 1.00 32.31  ? 49  SER B CB  1 
ATOM   3615  O  OG  . SER B 2 51  ? 258.552 250.077 273.061 1.00 33.71  ? 49  SER B OG  1 
ATOM   3616  N  N   . ASN B 2 52  ? 260.952 247.367 273.942 1.00 32.21  ? 50  ASN B N   1 
ATOM   3617  C  CA  . ASN B 2 52  ? 262.227 247.054 273.306 1.00 33.37  ? 50  ASN B CA  1 
ATOM   3618  C  C   . ASN B 2 52  ? 262.452 247.930 272.080 1.00 33.77  ? 50  ASN B C   1 
ATOM   3619  O  O   . ASN B 2 52  ? 263.576 248.380 271.825 1.00 36.12  ? 50  ASN B O   1 
ATOM   3620  C  CB  . ASN B 2 52  ? 262.276 245.572 272.937 1.00 34.82  ? 50  ASN B CB  1 
ATOM   3621  C  CG  . ASN B 2 52  ? 263.620 245.155 272.381 1.00 33.50  ? 50  ASN B CG  1 
ATOM   3622  O  OD1 . ASN B 2 52  ? 263.781 244.992 271.173 1.00 37.92  ? 50  ASN B OD1 1 
ATOM   3623  N  ND2 . ASN B 2 52  ? 264.598 244.989 273.261 1.00 36.63  ? 50  ASN B ND2 1 
ATOM   3624  N  N   . ARG B 2 53  ? 261.390 248.190 271.316 1.00 33.38  ? 51  ARG B N   1 
ATOM   3625  C  CA  . ARG B 2 53  ? 261.490 249.121 270.198 1.00 32.46  ? 51  ARG B CA  1 
ATOM   3626  C  C   . ARG B 2 53  ? 261.952 250.492 270.675 1.00 33.25  ? 51  ARG B C   1 
ATOM   3627  O  O   . ARG B 2 53  ? 262.851 251.100 270.084 1.00 35.44  ? 51  ARG B O   1 
ATOM   3628  C  CB  . ARG B 2 53  ? 260.139 249.231 269.489 1.00 30.72  ? 51  ARG B CB  1 
ATOM   3629  C  CG  . ARG B 2 53  ? 259.678 247.969 268.785 1.00 29.12  ? 51  ARG B CG  1 
ATOM   3630  C  CD  . ARG B 2 53  ? 260.469 247.715 267.520 1.00 27.12  ? 51  ARG B CD  1 
ATOM   3631  N  NE  . ARG B 2 53  ? 259.667 247.029 266.515 1.00 29.73  ? 51  ARG B NE  1 
ATOM   3632  C  CZ  . ARG B 2 53  ? 260.167 246.359 265.487 1.00 29.69  ? 51  ARG B CZ  1 
ATOM   3633  N  NH1 . ARG B 2 53  ? 261.472 246.262 265.294 1.00 32.44  ? 51  ARG B NH1 1 
ATOM   3634  N  NH2 . ARG B 2 53  ? 259.338 245.773 264.629 1.00 30.10  ? 51  ARG B NH2 1 
ATOM   3635  N  N   . ALA B 2 54  ? 261.342 250.993 271.752 1.00 32.37  ? 52  ALA B N   1 
ATOM   3636  C  CA  . ALA B 2 54  ? 261.701 252.311 272.264 1.00 31.00  ? 52  ALA B CA  1 
ATOM   3637  C  C   . ALA B 2 54  ? 263.130 252.333 272.788 1.00 34.26  ? 52  ALA B C   1 
ATOM   3638  O  O   . ALA B 2 54  ? 263.857 253.308 272.576 1.00 35.90  ? 52  ALA B O   1 
ATOM   3639  C  CB  . ALA B 2 54  ? 260.720 252.736 273.355 1.00 32.57  ? 52  ALA B CB  1 
ATOM   3640  N  N   . GLN B 2 55  ? 263.551 251.272 273.478 1.00 36.08  ? 53  GLN B N   1 
ATOM   3641  C  CA  . GLN B 2 55  ? 264.920 251.215 273.981 1.00 34.83  ? 53  GLN B CA  1 
ATOM   3642  C  C   . GLN B 2 55  ? 265.923 251.231 272.835 1.00 33.86  ? 53  GLN B C   1 
ATOM   3643  O  O   . GLN B 2 55  ? 266.916 251.969 272.869 1.00 36.43  ? 53  GLN B O   1 
ATOM   3644  C  CB  . GLN B 2 55  ? 265.106 249.967 274.843 1.00 35.57  ? 53  GLN B CB  1 
ATOM   3645  C  CG  . GLN B 2 55  ? 264.390 250.021 276.179 1.00 36.41  ? 53  GLN B CG  1 
ATOM   3646  C  CD  . GLN B 2 55  ? 264.170 248.647 276.775 1.00 41.89  ? 53  GLN B CD  1 
ATOM   3647  O  OE1 . GLN B 2 55  ? 264.817 247.677 276.382 1.00 39.97  ? 53  GLN B OE1 1 
ATOM   3648  N  NE2 . GLN B 2 55  ? 263.244 248.554 277.721 1.00 41.63  ? 53  GLN B NE2 1 
ATOM   3649  N  N   . GLU B 2 56  ? 265.679 250.416 271.807 1.00 36.62  ? 54  GLU B N   1 
ATOM   3650  C  CA  . GLU B 2 56  ? 266.583 250.380 270.662 1.00 35.80  ? 54  GLU B CA  1 
ATOM   3651  C  C   . GLU B 2 56  ? 266.627 251.732 269.962 1.00 37.58  ? 54  GLU B C   1 
ATOM   3652  O  O   . GLU B 2 56  ? 267.706 252.239 269.628 1.00 43.40  ? 54  GLU B O   1 
ATOM   3653  C  CB  . GLU B 2 56  ? 266.149 249.276 269.697 1.00 36.87  ? 54  GLU B CB  1 
ATOM   3654  C  CG  . GLU B 2 56  ? 267.266 248.722 268.835 1.00 49.42  ? 54  GLU B CG  1 
ATOM   3655  C  CD  . GLU B 2 56  ? 267.140 249.133 267.384 1.00 54.98  ? 54  GLU B CD  1 
ATOM   3656  O  OE1 . GLU B 2 56  ? 267.695 248.426 266.517 1.00 56.51  ? 54  GLU B OE1 1 
ATOM   3657  O  OE2 . GLU B 2 56  ? 266.486 250.160 267.108 1.00 56.43  ? 54  GLU B OE2 1 
ATOM   3658  N  N   . PHE B 2 57  ? 265.460 252.344 269.749 1.00 35.51  ? 55  PHE B N   1 
ATOM   3659  C  CA  . PHE B 2 57  ? 265.417 253.644 269.091 1.00 34.16  ? 55  PHE B CA  1 
ATOM   3660  C  C   . PHE B 2 57  ? 266.164 254.696 269.899 1.00 36.97  ? 55  PHE B C   1 
ATOM   3661  O  O   . PHE B 2 57  ? 266.919 255.497 269.339 1.00 40.33  ? 55  PHE B O   1 
ATOM   3662  C  CB  . PHE B 2 57  ? 263.965 254.067 268.868 1.00 37.18  ? 55  PHE B CB  1 
ATOM   3663  C  CG  . PHE B 2 57  ? 263.813 255.303 268.034 1.00 34.85  ? 55  PHE B CG  1 
ATOM   3664  C  CD1 . PHE B 2 57  ? 264.100 255.281 266.681 1.00 35.25  ? 55  PHE B CD1 1 
ATOM   3665  C  CD2 . PHE B 2 57  ? 263.379 256.487 268.601 1.00 32.79  ? 55  PHE B CD2 1 
ATOM   3666  C  CE1 . PHE B 2 57  ? 263.959 256.415 265.911 1.00 35.11  ? 55  PHE B CE1 1 
ATOM   3667  C  CE2 . PHE B 2 57  ? 263.236 257.624 267.835 1.00 35.20  ? 55  PHE B CE2 1 
ATOM   3668  C  CZ  . PHE B 2 57  ? 263.525 257.588 266.489 1.00 32.01  ? 55  PHE B CZ  1 
ATOM   3669  N  N   . ASN B 2 58  ? 265.967 254.710 271.220 1.00 37.98  ? 56  ASN B N   1 
ATOM   3670  C  CA  . ASN B 2 58  ? 266.640 255.692 272.061 1.00 37.06  ? 56  ASN B CA  1 
ATOM   3671  C  C   . ASN B 2 58  ? 268.149 255.503 272.023 1.00 38.61  ? 56  ASN B C   1 
ATOM   3672  O  O   . ASN B 2 58  ? 268.903 256.467 271.846 1.00 40.65  ? 56  ASN B O   1 
ATOM   3673  C  CB  . ASN B 2 58  ? 266.122 255.596 273.495 1.00 33.92  ? 56  ASN B CB  1 
ATOM   3674  C  CG  . ASN B 2 58  ? 264.813 256.329 273.689 1.00 42.94  ? 56  ASN B CG  1 
ATOM   3675  O  OD1 . ASN B 2 58  ? 264.518 257.295 272.985 1.00 48.08  ? 56  ASN B OD1 1 
ATOM   3676  N  ND2 . ASN B 2 58  ? 264.015 255.871 274.645 1.00 48.26  ? 56  ASN B ND2 1 
ATOM   3677  N  N   . ARG B 2 59  ? 268.615 254.264 272.189 1.00 40.03  ? 57  ARG B N   1 
ATOM   3678  C  CA  . ARG B 2 59  ? 270.050 254.026 272.143 1.00 40.49  ? 57  ARG B CA  1 
ATOM   3679  C  C   . ARG B 2 59  ? 270.620 254.260 270.751 1.00 39.10  ? 57  ARG B C   1 
ATOM   3680  O  O   . ARG B 2 59  ? 271.841 254.382 270.607 1.00 45.35  ? 57  ARG B O   1 
ATOM   3681  C  CB  . ARG B 2 59  ? 270.371 252.613 272.631 1.00 39.21  ? 57  ARG B CB  1 
ATOM   3682  C  CG  . ARG B 2 59  ? 270.692 251.616 271.539 1.00 40.41  ? 57  ARG B CG  1 
ATOM   3683  C  CD  . ARG B 2 59  ? 271.235 250.330 272.139 1.00 40.73  ? 57  ARG B CD  1 
ATOM   3684  N  NE  . ARG B 2 59  ? 270.316 249.747 273.109 1.00 45.80  ? 57  ARG B NE  1 
ATOM   3685  C  CZ  . ARG B 2 59  ? 269.507 248.727 272.858 1.00 46.46  ? 57  ARG B CZ  1 
ATOM   3686  N  NH1 . ARG B 2 59  ? 269.471 248.150 271.669 1.00 43.00  ? 57  ARG B NH1 1 
ATOM   3687  N  NH2 . ARG B 2 59  ? 268.713 248.276 273.825 1.00 39.97  ? 57  ARG B NH2 1 
ATOM   3688  N  N   . ARG B 2 60  ? 269.768 254.327 269.728 1.00 41.59  ? 58  ARG B N   1 
ATOM   3689  C  CA  . ARG B 2 60  ? 270.221 254.728 268.402 1.00 42.15  ? 58  ARG B CA  1 
ATOM   3690  C  C   . ARG B 2 60  ? 270.335 256.242 268.253 1.00 42.23  ? 58  ARG B C   1 
ATOM   3691  O  O   . ARG B 2 60  ? 270.988 256.710 267.315 1.00 45.12  ? 58  ARG B O   1 
ATOM   3692  C  CB  . ARG B 2 60  ? 269.272 254.172 267.337 1.00 39.19  ? 58  ARG B CB  1 
ATOM   3693  C  CG  . ARG B 2 60  ? 269.455 254.773 265.957 1.00 38.79  ? 58  ARG B CG  1 
ATOM   3694  C  CD  . ARG B 2 60  ? 269.030 253.805 264.867 1.00 41.06  ? 58  ARG B CD  1 
ATOM   3695  N  NE  . ARG B 2 60  ? 267.829 253.064 265.231 1.00 44.41  ? 58  ARG B NE  1 
ATOM   3696  C  CZ  . ARG B 2 60  ? 266.620 253.317 264.751 1.00 43.42  ? 58  ARG B CZ  1 
ATOM   3697  N  NH1 . ARG B 2 60  ? 266.411 254.291 263.880 1.00 41.56  ? 58  ARG B NH1 1 
ATOM   3698  N  NH2 . ARG B 2 60  ? 265.593 252.576 265.156 1.00 43.38  ? 58  ARG B NH2 1 
ATOM   3699  N  N   . LEU B 2 61  ? 269.731 257.013 269.156 1.00 43.84  ? 59  LEU B N   1 
ATOM   3700  C  CA  . LEU B 2 61  ? 269.703 258.467 269.063 1.00 38.91  ? 59  LEU B CA  1 
ATOM   3701  C  C   . LEU B 2 61  ? 270.724 259.145 269.969 1.00 43.23  ? 59  LEU B C   1 
ATOM   3702  O  O   . LEU B 2 61  ? 270.719 260.375 270.075 1.00 45.33  ? 59  LEU B O   1 
ATOM   3703  C  CB  . LEU B 2 61  ? 268.302 258.988 269.390 1.00 40.50  ? 59  LEU B CB  1 
ATOM   3704  C  CG  . LEU B 2 61  ? 267.226 258.806 268.319 1.00 44.39  ? 59  LEU B CG  1 
ATOM   3705  C  CD1 . LEU B 2 61  ? 265.933 259.473 268.750 1.00 40.41  ? 59  LEU B CD1 1 
ATOM   3706  C  CD2 . LEU B 2 61  ? 267.695 259.354 266.981 1.00 40.95  ? 59  LEU B CD2 1 
ATOM   3707  N  N   . THR B 2 62  ? 271.589 258.380 270.626 1.00 45.80  ? 60  THR B N   1 
ATOM   3708  C  CA  . THR B 2 62  ? 272.586 258.964 271.511 1.00 47.95  ? 60  THR B CA  1 
ATOM   3709  C  C   . THR B 2 62  ? 273.813 259.397 270.720 1.00 48.88  ? 60  THR B C   1 
ATOM   3710  O  O   . THR B 2 62  ? 274.213 258.739 269.755 1.00 52.41  ? 60  THR B O   1 
ATOM   3711  C  CB  . THR B 2 62  ? 272.989 257.968 272.598 1.00 51.06  ? 60  THR B CB  1 
ATOM   3712  O  OG1 . THR B 2 62  ? 273.921 257.022 272.060 1.00 52.12  ? 60  THR B OG1 1 
ATOM   3713  C  CG2 . THR B 2 62  ? 271.768 257.231 273.120 1.00 44.10  ? 60  THR B CG2 1 
ATOM   3714  N  N   . GLN B 2 63  ? 274.410 260.510 271.136 1.00 48.01  ? 61  GLN B N   1 
ATOM   3715  C  CA  . GLN B 2 63  ? 275.595 261.047 270.481 1.00 49.53  ? 61  GLN B CA  1 
ATOM   3716  C  C   . GLN B 2 63  ? 276.844 260.412 271.074 1.00 51.45  ? 61  GLN B C   1 
ATOM   3717  O  O   . GLN B 2 63  ? 277.026 260.406 272.295 1.00 53.36  ? 61  GLN B O   1 
ATOM   3718  C  CB  . GLN B 2 63  ? 275.659 262.566 270.629 1.00 42.85  ? 61  GLN B CB  1 
ATOM   3719  C  CG  . GLN B 2 63  ? 274.313 263.238 270.787 1.00 38.53  ? 61  GLN B CG  1 
ATOM   3720  C  CD  . GLN B 2 63  ? 274.416 264.748 270.767 1.00 37.18  ? 61  GLN B CD  1 
ATOM   3721  O  OE1 . GLN B 2 63  ? 275.035 265.327 269.877 1.00 34.86  ? 61  GLN B OE1 1 
ATOM   3722  N  NE2 . GLN B 2 63  ? 273.814 265.394 271.756 1.00 35.87  ? 61  GLN B NE2 1 
ATOM   3723  N  N   . LYS B 2 64  ? 277.701 259.881 270.207 1.00 51.90  ? 62  LYS B N   1 
ATOM   3724  C  CA  . LYS B 2 64  ? 278.946 259.247 270.613 1.00 54.85  ? 62  LYS B CA  1 
ATOM   3725  C  C   . LYS B 2 64  ? 280.124 260.071 270.113 1.00 56.39  ? 62  LYS B C   1 
ATOM   3726  O  O   . LYS B 2 64  ? 280.213 260.373 268.918 1.00 54.60  ? 62  LYS B O   1 
ATOM   3727  C  CB  . LYS B 2 64  ? 279.035 257.818 270.076 1.00 60.81  ? 62  LYS B CB  1 
ATOM   3728  C  CG  . LYS B 2 64  ? 278.058 256.848 270.721 1.00 58.93  ? 62  LYS B CG  1 
ATOM   3729  C  CD  . LYS B 2 64  ? 277.055 256.318 269.711 1.00 59.31  ? 62  LYS B CD  1 
ATOM   3730  C  CE  . LYS B 2 64  ? 276.204 255.211 270.311 1.00 64.26  ? 62  LYS B CE  1 
ATOM   3731  N  NZ  . LYS B 2 64  ? 274.845 255.161 269.704 1.00 56.43  ? 62  LYS B NZ  1 
ATOM   3732  N  N   . THR B 2 65  ? 281.020 260.431 271.026 1.00 53.85  ? 63  THR B N   1 
ATOM   3733  C  CA  . THR B 2 65  ? 282.234 261.176 270.717 1.00 52.10  ? 63  THR B CA  1 
ATOM   3734  C  C   . THR B 2 65  ? 283.468 260.329 271.007 1.00 54.67  ? 63  THR B C   1 
ATOM   3735  O  O   . THR B 2 65  ? 284.514 260.835 271.419 1.00 54.14  ? 63  THR B O   1 
ATOM   3736  C  CB  . THR B 2 65  ? 282.281 262.487 271.499 1.00 51.42  ? 63  THR B CB  1 
ATOM   3737  O  OG1 . THR B 2 65  ? 282.901 262.266 272.772 1.00 58.51  ? 63  THR B OG1 1 
ATOM   3738  C  CG2 . THR B 2 65  ? 280.876 263.024 271.722 1.00 43.36  ? 63  THR B CG2 1 
ATOM   3739  N  N   . ASP B 2 66  ? 283.352 259.019 270.785 1.00 56.73  ? 64  ASP B N   1 
ATOM   3740  C  CA  . ASP B 2 66  ? 284.397 258.090 271.204 1.00 62.12  ? 64  ASP B CA  1 
ATOM   3741  C  C   . ASP B 2 66  ? 285.703 258.338 270.457 1.00 59.22  ? 64  ASP B C   1 
ATOM   3742  O  O   . ASP B 2 66  ? 286.767 258.481 271.071 1.00 57.19  ? 64  ASP B O   1 
ATOM   3743  C  CB  . ASP B 2 66  ? 283.925 256.650 270.996 1.00 68.88  ? 64  ASP B CB  1 
ATOM   3744  C  CG  . ASP B 2 66  ? 283.505 255.982 272.288 1.00 79.43  ? 64  ASP B CG  1 
ATOM   3745  O  OD1 . ASP B 2 66  ? 284.101 256.291 273.342 1.00 78.41  ? 64  ASP B OD1 1 
ATOM   3746  O  OD2 . ASP B 2 66  ? 282.578 255.146 272.250 1.00 82.24  ? 64  ASP B OD2 1 
ATOM   3747  N  N   . ASN B 2 67  ? 285.644 258.388 269.127 1.00 54.12  ? 65  ASN B N   1 
ATOM   3748  C  CA  . ASN B 2 67  ? 286.839 258.460 268.295 1.00 50.18  ? 65  ASN B CA  1 
ATOM   3749  C  C   . ASN B 2 67  ? 286.937 259.779 267.535 1.00 43.02  ? 65  ASN B C   1 
ATOM   3750  O  O   . ASN B 2 67  ? 287.476 259.824 266.428 1.00 42.61  ? 65  ASN B O   1 
ATOM   3751  C  CB  . ASN B 2 67  ? 286.875 257.284 267.320 1.00 54.41  ? 65  ASN B CB  1 
ATOM   3752  C  CG  . ASN B 2 67  ? 287.485 256.041 267.932 1.00 58.14  ? 65  ASN B CG  1 
ATOM   3753  O  OD1 . ASN B 2 67  ? 286.825 255.315 268.676 1.00 57.39  ? 65  ASN B OD1 1 
ATOM   3754  N  ND2 . ASN B 2 67  ? 288.751 255.788 267.624 1.00 53.16  ? 65  ASN B ND2 1 
ATOM   3755  N  N   . ALA B 2 68  ? 286.421 260.856 268.111 1.00 45.25  ? 66  ALA B N   1 
ATOM   3756  C  CA  . ALA B 2 68  ? 286.486 262.148 267.448 1.00 34.97  ? 66  ALA B CA  1 
ATOM   3757  C  C   . ALA B 2 68  ? 287.939 262.594 267.311 1.00 36.29  ? 66  ALA B C   1 
ATOM   3758  O  O   . ALA B 2 68  ? 288.683 262.578 268.301 1.00 36.93  ? 66  ALA B O   1 
ATOM   3759  C  CB  . ALA B 2 68  ? 285.684 263.190 268.225 1.00 33.06  ? 66  ALA B CB  1 
ATOM   3760  N  N   . PRO B 2 69  ? 288.384 262.990 266.115 1.00 35.18  ? 67  PRO B N   1 
ATOM   3761  C  CA  . PRO B 2 69  ? 289.748 263.525 265.984 1.00 29.07  ? 67  PRO B CA  1 
ATOM   3762  C  C   . PRO B 2 69  ? 289.911 264.914 266.574 1.00 33.32  ? 67  PRO B C   1 
ATOM   3763  O  O   . PRO B 2 69  ? 291.049 265.370 266.730 1.00 37.44  ? 67  PRO B O   1 
ATOM   3764  C  CB  . PRO B 2 69  ? 289.985 263.536 264.465 1.00 27.27  ? 67  PRO B CB  1 
ATOM   3765  C  CG  . PRO B 2 69  ? 288.800 262.843 263.851 1.00 31.32  ? 67  PRO B CG  1 
ATOM   3766  C  CD  . PRO B 2 69  ? 287.680 262.948 264.826 1.00 30.58  ? 67  PRO B CD  1 
ATOM   3767  N  N   . TRP B 2 70  ? 288.817 265.598 266.900 1.00 30.26  ? 68  TRP B N   1 
ATOM   3768  C  CA  . TRP B 2 70  ? 288.863 266.946 267.444 1.00 29.33  ? 68  TRP B CA  1 
ATOM   3769  C  C   . TRP B 2 70  ? 287.782 267.099 268.503 1.00 30.89  ? 68  TRP B C   1 
ATOM   3770  O  O   . TRP B 2 70  ? 286.662 266.611 268.332 1.00 34.70  ? 68  TRP B O   1 
ATOM   3771  C  CB  . TRP B 2 70  ? 288.682 267.993 266.338 1.00 26.74  ? 68  TRP B CB  1 
ATOM   3772  C  CG  . TRP B 2 70  ? 288.567 269.396 266.839 1.00 26.56  ? 68  TRP B CG  1 
ATOM   3773  C  CD1 . TRP B 2 70  ? 289.587 270.250 267.127 1.00 28.28  ? 68  TRP B CD1 1 
ATOM   3774  C  CD2 . TRP B 2 70  ? 287.357 270.112 267.102 1.00 28.90  ? 68  TRP B CD2 1 
ATOM   3775  N  NE1 . TRP B 2 70  ? 289.089 271.454 267.560 1.00 27.22  ? 68  TRP B NE1 1 
ATOM   3776  C  CE2 . TRP B 2 70  ? 287.721 271.394 267.553 1.00 27.34  ? 68  TRP B CE2 1 
ATOM   3777  C  CE3 . TRP B 2 70  ? 286.001 269.792 267.003 1.00 26.49  ? 68  TRP B CE3 1 
ATOM   3778  C  CZ2 . TRP B 2 70  ? 286.778 272.356 267.902 1.00 24.38  ? 68  TRP B CZ2 1 
ATOM   3779  C  CZ3 . TRP B 2 70  ? 285.069 270.746 267.351 1.00 25.59  ? 68  TRP B CZ3 1 
ATOM   3780  C  CH2 . TRP B 2 70  ? 285.460 272.013 267.794 1.00 25.83  ? 68  TRP B CH2 1 
ATOM   3781  N  N   . ARG B 2 71  ? 288.126 267.771 269.599 1.00 33.00  ? 69  ARG B N   1 
ATOM   3782  C  CA  . ARG B 2 71  ? 287.188 267.986 270.691 1.00 30.69  ? 69  ARG B CA  1 
ATOM   3783  C  C   . ARG B 2 71  ? 287.454 269.346 271.315 1.00 29.72  ? 69  ARG B C   1 
ATOM   3784  O  O   . ARG B 2 71  ? 288.557 269.889 271.223 1.00 31.98  ? 69  ARG B O   1 
ATOM   3785  C  CB  . ARG B 2 71  ? 287.301 266.893 271.760 1.00 33.75  ? 69  ARG B CB  1 
ATOM   3786  C  CG  . ARG B 2 71  ? 286.471 265.657 271.494 1.00 38.29  ? 69  ARG B CG  1 
ATOM   3787  C  CD  . ARG B 2 71  ? 286.425 264.771 272.723 1.00 44.71  ? 69  ARG B CD  1 
ATOM   3788  N  NE  . ARG B 2 71  ? 287.494 265.087 273.661 1.00 47.18  ? 69  ARG B NE  1 
ATOM   3789  C  CZ  . ARG B 2 71  ? 287.303 265.410 274.933 1.00 49.74  ? 69  ARG B CZ  1 
ATOM   3790  N  NH1 . ARG B 2 71  ? 286.090 265.474 275.455 1.00 45.74  ? 69  ARG B NH1 1 
ATOM   3791  N  NH2 . ARG B 2 71  ? 288.356 265.672 275.702 1.00 48.74  ? 69  ARG B NH2 1 
ATOM   3792  N  N   . ARG B 2 72  ? 286.424 269.892 271.959 1.00 30.50  ? 70  ARG B N   1 
ATOM   3793  C  CA  . ARG B 2 72  ? 286.583 271.127 272.717 1.00 27.12  ? 70  ARG B CA  1 
ATOM   3794  C  C   . ARG B 2 72  ? 285.464 271.229 273.740 1.00 27.27  ? 70  ARG B C   1 
ATOM   3795  O  O   . ARG B 2 72  ? 284.288 271.148 273.381 1.00 32.70  ? 70  ARG B O   1 
ATOM   3796  C  CB  . ARG B 2 72  ? 286.583 272.347 271.792 1.00 25.60  ? 70  ARG B CB  1 
ATOM   3797  C  CG  . ARG B 2 72  ? 287.972 272.790 271.369 1.00 28.25  ? 70  ARG B CG  1 
ATOM   3798  C  CD  . ARG B 2 72  ? 287.986 274.242 270.949 1.00 29.97  ? 70  ARG B CD  1 
ATOM   3799  N  NE  . ARG B 2 72  ? 288.569 275.102 271.971 1.00 33.35  ? 70  ARG B NE  1 
ATOM   3800  C  CZ  . ARG B 2 72  ? 288.690 276.416 271.858 1.00 36.42  ? 70  ARG B CZ  1 
ATOM   3801  N  NH1 . ARG B 2 72  ? 288.268 277.059 270.782 1.00 36.80  ? 70  ARG B NH1 1 
ATOM   3802  N  NH2 . ARG B 2 72  ? 289.250 277.103 272.849 1.00 32.54  ? 70  ARG B NH2 1 
ATOM   3803  N  N   . VAL B 2 73  ? 285.829 271.421 275.003 1.00 28.42  ? 71  VAL B N   1 
ATOM   3804  C  CA  . VAL B 2 73  ? 284.867 271.521 276.095 1.00 28.65  ? 71  VAL B CA  1 
ATOM   3805  C  C   . VAL B 2 73  ? 284.693 272.987 276.460 1.00 31.78  ? 71  VAL B C   1 
ATOM   3806  O  O   . VAL B 2 73  ? 285.678 273.718 276.619 1.00 36.03  ? 71  VAL B O   1 
ATOM   3807  C  CB  . VAL B 2 73  ? 285.319 270.697 277.312 1.00 29.67  ? 71  VAL B CB  1 
ATOM   3808  C  CG1 . VAL B 2 73  ? 284.509 271.080 278.537 1.00 30.80  ? 71  VAL B CG1 1 
ATOM   3809  C  CG2 . VAL B 2 73  ? 285.182 269.214 277.021 1.00 28.55  ? 71  VAL B CG2 1 
ATOM   3810  N  N   . VAL B 2 74  ? 283.440 273.418 276.586 1.00 30.99  ? 72  VAL B N   1 
ATOM   3811  C  CA  . VAL B 2 74  ? 283.099 274.813 276.839 1.00 28.62  ? 72  VAL B CA  1 
ATOM   3812  C  C   . VAL B 2 74  ? 282.082 274.874 277.970 1.00 31.08  ? 72  VAL B C   1 
ATOM   3813  O  O   . VAL B 2 74  ? 281.077 274.157 277.947 1.00 35.43  ? 72  VAL B O   1 
ATOM   3814  C  CB  . VAL B 2 74  ? 282.544 275.495 275.574 1.00 31.10  ? 72  VAL B CB  1 
ATOM   3815  C  CG1 . VAL B 2 74  ? 282.151 276.928 275.871 1.00 34.23  ? 72  VAL B CG1 1 
ATOM   3816  C  CG2 . VAL B 2 74  ? 283.570 275.441 274.455 1.00 35.46  ? 72  VAL B CG2 1 
ATOM   3817  N  N   . TYR B 2 75  ? 282.338 275.730 278.955 1.00 30.94  ? 73  TYR B N   1 
ATOM   3818  C  CA  . TYR B 2 75  ? 281.407 275.988 280.047 1.00 27.56  ? 73  TYR B CA  1 
ATOM   3819  C  C   . TYR B 2 75  ? 280.755 277.337 279.784 1.00 30.88  ? 73  TYR B C   1 
ATOM   3820  O  O   . TYR B 2 75  ? 281.412 278.380 279.892 1.00 33.27  ? 73  TYR B O   1 
ATOM   3821  C  CB  . TYR B 2 75  ? 282.118 275.996 281.398 1.00 25.46  ? 73  TYR B CB  1 
ATOM   3822  C  CG  . TYR B 2 75  ? 282.878 274.738 281.735 1.00 30.65  ? 73  TYR B CG  1 
ATOM   3823  C  CD1 . TYR B 2 75  ? 284.039 274.400 281.053 1.00 29.54  ? 73  TYR B CD1 1 
ATOM   3824  C  CD2 . TYR B 2 75  ? 282.454 273.903 282.759 1.00 30.65  ? 73  TYR B CD2 1 
ATOM   3825  C  CE1 . TYR B 2 75  ? 284.742 273.259 281.365 1.00 28.64  ? 73  TYR B CE1 1 
ATOM   3826  C  CE2 . TYR B 2 75  ? 283.152 272.760 283.080 1.00 33.35  ? 73  TYR B CE2 1 
ATOM   3827  C  CZ  . TYR B 2 75  ? 284.295 272.442 282.380 1.00 34.13  ? 73  TYR B CZ  1 
ATOM   3828  O  OH  . TYR B 2 75  ? 284.994 271.302 282.697 1.00 39.30  ? 73  TYR B OH  1 
ATOM   3829  N  N   . ARG B 2 76  ? 279.469 277.310 279.446 1.00 30.96  ? 74  ARG B N   1 
ATOM   3830  C  CA  . ARG B 2 76  ? 278.683 278.497 279.154 1.00 30.24  ? 74  ARG B CA  1 
ATOM   3831  C  C   . ARG B 2 76  ? 277.769 278.826 280.326 1.00 30.49  ? 74  ARG B C   1 
ATOM   3832  O  O   . ARG B 2 76  ? 277.340 277.942 281.071 1.00 31.78  ? 74  ARG B O   1 
ATOM   3833  C  CB  . ARG B 2 76  ? 277.836 278.292 277.897 1.00 31.09  ? 74  ARG B CB  1 
ATOM   3834  C  CG  . ARG B 2 76  ? 278.597 278.343 276.590 1.00 36.06  ? 74  ARG B CG  1 
ATOM   3835  C  CD  . ARG B 2 76  ? 277.627 278.370 275.424 1.00 33.47  ? 74  ARG B CD  1 
ATOM   3836  N  NE  . ARG B 2 76  ? 278.277 278.091 274.151 1.00 37.39  ? 74  ARG B NE  1 
ATOM   3837  C  CZ  . ARG B 2 76  ? 278.838 279.012 273.381 1.00 38.46  ? 74  ARG B CZ  1 
ATOM   3838  N  NH1 . ARG B 2 76  ? 278.841 280.289 273.722 1.00 40.03  ? 74  ARG B NH1 1 
ATOM   3839  N  NH2 . ARG B 2 76  ? 279.404 278.642 272.236 1.00 37.64  ? 74  ARG B NH2 1 
ATOM   3840  N  N   . ARG B 2 77  ? 277.468 280.111 280.477 1.00 33.30  ? 75  ARG B N   1 
ATOM   3841  C  CA  . ARG B 2 77  ? 276.509 280.589 281.464 1.00 33.80  ? 75  ARG B CA  1 
ATOM   3842  C  C   . ARG B 2 77  ? 275.274 281.093 280.732 1.00 36.47  ? 75  ARG B C   1 
ATOM   3843  O  O   . ARG B 2 77  ? 275.355 282.060 279.967 1.00 37.26  ? 75  ARG B O   1 
ATOM   3844  C  CB  . ARG B 2 77  ? 277.113 281.693 282.330 1.00 34.43  ? 75  ARG B CB  1 
ATOM   3845  C  CG  . ARG B 2 77  ? 276.285 282.049 283.548 1.00 35.96  ? 75  ARG B CG  1 
ATOM   3846  C  CD  . ARG B 2 77  ? 276.998 283.073 284.410 1.00 38.18  ? 75  ARG B CD  1 
ATOM   3847  N  NE  . ARG B 2 77  ? 276.262 283.371 285.633 1.00 43.61  ? 75  ARG B NE  1 
ATOM   3848  C  CZ  . ARG B 2 77  ? 275.256 284.231 285.709 1.00 48.12  ? 75  ARG B CZ  1 
ATOM   3849  N  NH1 . ARG B 2 77  ? 274.838 284.901 284.648 1.00 44.99  ? 75  ARG B NH1 1 
ATOM   3850  N  NH2 . ARG B 2 77  ? 274.657 284.426 286.880 1.00 51.57  ? 75  ARG B NH2 1 
ATOM   3851  N  N   . VAL B 2 78  ? 274.139 280.443 280.965 1.00 36.41  ? 76  VAL B N   1 
ATOM   3852  C  CA  . VAL B 2 78  ? 272.881 280.812 280.330 1.00 36.66  ? 76  VAL B CA  1 
ATOM   3853  C  C   . VAL B 2 78  ? 272.053 281.586 281.345 1.00 39.49  ? 76  VAL B C   1 
ATOM   3854  O  O   . VAL B 2 78  ? 271.770 281.089 282.442 1.00 37.82  ? 76  VAL B O   1 
ATOM   3855  C  CB  . VAL B 2 78  ? 272.128 279.578 279.804 1.00 38.11  ? 76  VAL B CB  1 
ATOM   3856  C  CG1 . VAL B 2 78  ? 273.094 278.626 279.112 1.00 40.47  ? 76  VAL B CG1 1 
ATOM   3857  C  CG2 . VAL B 2 78  ? 271.389 278.869 280.924 1.00 40.09  ? 76  VAL B CG2 1 
ATOM   3858  N  N   . ASP B 2 79  ? 271.687 282.814 280.987 1.00 42.77  ? 77  ASP B N   1 
ATOM   3859  C  CA  . ASP B 2 79  ? 270.932 283.697 281.864 1.00 45.32  ? 77  ASP B CA  1 
ATOM   3860  C  C   . ASP B 2 79  ? 269.443 283.529 281.587 1.00 46.41  ? 77  ASP B C   1 
ATOM   3861  O  O   . ASP B 2 79  ? 268.980 283.788 280.471 1.00 47.33  ? 77  ASP B O   1 
ATOM   3862  C  CB  . ASP B 2 79  ? 271.364 285.148 281.658 1.00 50.81  ? 77  ASP B CB  1 
ATOM   3863  C  CG  . ASP B 2 79  ? 270.741 286.093 282.665 1.00 59.49  ? 77  ASP B CG  1 
ATOM   3864  O  OD1 . ASP B 2 79  ? 270.438 285.651 283.793 1.00 56.68  ? 77  ASP B OD1 1 
ATOM   3865  O  OD2 . ASP B 2 79  ? 270.556 287.280 282.326 1.00 60.63  ? 77  ASP B OD2 1 
ATOM   3866  N  N   . LEU B 2 80  ? 268.695 283.099 282.605 1.00 44.31  ? 78  LEU B N   1 
ATOM   3867  C  CA  . LEU B 2 80  ? 267.269 282.843 282.450 1.00 46.92  ? 78  LEU B CA  1 
ATOM   3868  C  C   . LEU B 2 80  ? 266.453 284.112 282.257 1.00 48.84  ? 78  LEU B C   1 
ATOM   3869  O  O   . LEU B 2 80  ? 265.279 284.019 281.885 1.00 50.79  ? 78  LEU B O   1 
ATOM   3870  C  CB  . LEU B 2 80  ? 266.743 282.074 283.662 1.00 46.05  ? 78  LEU B CB  1 
ATOM   3871  C  CG  . LEU B 2 80  ? 267.359 280.694 283.890 1.00 40.22  ? 78  LEU B CG  1 
ATOM   3872  C  CD1 . LEU B 2 80  ? 266.460 279.848 284.771 1.00 37.81  ? 78  LEU B CD1 1 
ATOM   3873  C  CD2 . LEU B 2 80  ? 267.624 279.999 282.565 1.00 40.29  ? 78  LEU B CD2 1 
ATOM   3874  N  N   . MET B 2 81  ? 267.033 285.287 282.496 1.00 52.70  ? 79  MET B N   1 
ATOM   3875  C  CA  . MET B 2 81  ? 266.323 286.548 282.354 1.00 51.16  ? 79  MET B CA  1 
ATOM   3876  C  C   . MET B 2 81  ? 266.345 287.076 280.925 1.00 54.20  ? 79  MET B C   1 
ATOM   3877  O  O   . MET B 2 81  ? 266.119 288.272 280.710 1.00 62.09  ? 79  MET B O   1 
ATOM   3878  C  CB  . MET B 2 81  ? 266.904 287.590 283.311 1.00 51.59  ? 79  MET B CB  1 
ATOM   3879  C  CG  . MET B 2 81  ? 266.630 287.297 284.775 1.00 58.29  ? 79  MET B CG  1 
ATOM   3880  S  SD  . MET B 2 81  ? 264.868 287.272 285.159 1.00 81.02  ? 79  MET B SD  1 
ATOM   3881  C  CE  . MET B 2 81  ? 264.552 285.511 285.214 1.00 54.38  ? 79  MET B CE  1 
ATOM   3882  N  N   . GLU B 2 82  ? 266.609 286.213 279.949 1.00 56.90  ? 80  GLU B N   1 
ATOM   3883  C  CA  . GLU B 2 82  ? 266.607 286.582 278.543 1.00 55.65  ? 80  GLU B CA  1 
ATOM   3884  C  C   . GLU B 2 82  ? 265.587 285.735 277.798 1.00 53.39  ? 80  GLU B C   1 
ATOM   3885  O  O   . GLU B 2 82  ? 265.487 284.526 278.027 1.00 53.40  ? 80  GLU B O   1 
ATOM   3886  C  CB  . GLU B 2 82  ? 267.988 286.393 277.912 1.00 55.30  ? 80  GLU B CB  1 
ATOM   3887  C  CG  . GLU B 2 82  ? 269.094 287.188 278.572 1.00 62.27  ? 80  GLU B CG  1 
ATOM   3888  C  CD  . GLU B 2 82  ? 270.449 286.893 277.969 1.00 71.27  ? 80  GLU B CD  1 
ATOM   3889  O  OE1 . GLU B 2 82  ? 270.495 286.230 276.911 1.00 69.63  ? 80  GLU B OE1 1 
ATOM   3890  O  OE2 . GLU B 2 82  ? 271.468 287.320 278.550 1.00 74.30  ? 80  GLU B OE2 1 
ATOM   3891  N  N   . GLU B 2 83  ? 264.830 286.372 276.909 1.00 58.28  ? 81  GLU B N   1 
ATOM   3892  C  CA  . GLU B 2 83  ? 263.922 285.624 276.055 1.00 56.52  ? 81  GLU B CA  1 
ATOM   3893  C  C   . GLU B 2 83  ? 264.711 284.643 275.195 1.00 58.01  ? 81  GLU B C   1 
ATOM   3894  O  O   . GLU B 2 83  ? 265.839 284.916 274.778 1.00 59.91  ? 81  GLU B O   1 
ATOM   3895  C  CB  . GLU B 2 83  ? 263.106 286.572 275.177 1.00 54.83  ? 81  GLU B CB  1 
ATOM   3896  C  CG  . GLU B 2 83  ? 262.248 285.868 274.140 1.00 57.83  ? 81  GLU B CG  1 
ATOM   3897  C  CD  . GLU B 2 83  ? 260.804 285.721 274.576 1.00 59.88  ? 81  GLU B CD  1 
ATOM   3898  O  OE1 . GLU B 2 83  ? 260.460 286.201 275.677 1.00 60.26  ? 81  GLU B OE1 1 
ATOM   3899  O  OE2 . GLU B 2 83  ? 260.012 285.122 273.819 1.00 50.57  ? 81  GLU B OE2 1 
ATOM   3900  N  N   . SER B 2 84  ? 264.104 283.489 274.932 1.00 55.83  ? 82  SER B N   1 
ATOM   3901  C  CA  . SER B 2 84  ? 264.726 282.316 274.324 1.00 57.52  ? 82  SER B CA  1 
ATOM   3902  C  C   . SER B 2 84  ? 265.566 281.560 275.347 1.00 52.46  ? 82  SER B C   1 
ATOM   3903  O  O   . SER B 2 84  ? 266.099 280.494 275.021 1.00 55.42  ? 82  SER B O   1 
ATOM   3904  C  CB  . SER B 2 84  ? 265.599 282.659 273.106 1.00 57.28  ? 82  SER B CB  1 
ATOM   3905  O  OG  . SER B 2 84  ? 266.929 282.954 273.498 1.00 55.75  ? 82  SER B OG  1 
ATOM   3906  N  N   . ASN B 2 85  ? 265.706 282.077 276.568 1.00 45.43  ? 83  ASN B N   1 
ATOM   3907  C  CA  . ASN B 2 85  ? 266.307 281.350 277.675 1.00 42.98  ? 83  ASN B CA  1 
ATOM   3908  C  C   . ASN B 2 85  ? 265.342 281.093 278.820 1.00 43.55  ? 83  ASN B C   1 
ATOM   3909  O  O   . ASN B 2 85  ? 265.587 280.178 279.613 1.00 42.95  ? 83  ASN B O   1 
ATOM   3910  C  CB  . ASN B 2 85  ? 267.525 282.106 278.226 1.00 49.15  ? 83  ASN B CB  1 
ATOM   3911  C  CG  . ASN B 2 85  ? 268.798 281.799 277.465 1.00 46.92  ? 83  ASN B CG  1 
ATOM   3912  O  OD1 . ASN B 2 85  ? 268.796 281.023 276.510 1.00 48.02  ? 83  ASN B OD1 1 
ATOM   3913  N  ND2 . ASN B 2 85  ? 269.897 282.408 277.890 1.00 44.15  ? 83  ASN B ND2 1 
ATOM   3914  N  N   . ALA B 2 86  ? 264.265 281.871 278.933 1.00 46.15  ? 84  ALA B N   1 
ATOM   3915  C  CA  . ALA B 2 86  ? 263.258 281.662 279.964 1.00 39.96  ? 84  ALA B CA  1 
ATOM   3916  C  C   . ALA B 2 86  ? 262.420 280.417 279.722 1.00 38.54  ? 84  ALA B C   1 
ATOM   3917  O  O   . ALA B 2 86  ? 261.523 280.131 280.522 1.00 42.97  ? 84  ALA B O   1 
ATOM   3918  C  CB  . ALA B 2 86  ? 262.352 282.889 280.066 1.00 37.68  ? 84  ALA B CB  1 
ATOM   3919  N  N   . VAL B 2 87  ? 262.684 279.677 278.644 1.00 37.04  ? 85  VAL B N   1 
ATOM   3920  C  CA  . VAL B 2 87  ? 262.011 278.399 278.437 1.00 34.12  ? 85  VAL B CA  1 
ATOM   3921  C  C   . VAL B 2 87  ? 262.245 277.484 279.630 1.00 36.76  ? 85  VAL B C   1 
ATOM   3922  O  O   . VAL B 2 87  ? 261.363 276.714 280.025 1.00 42.74  ? 85  VAL B O   1 
ATOM   3923  C  CB  . VAL B 2 87  ? 262.485 277.752 277.123 1.00 35.53  ? 85  VAL B CB  1 
ATOM   3924  C  CG1 . VAL B 2 87  ? 261.797 276.416 276.911 1.00 37.99  ? 85  VAL B CG1 1 
ATOM   3925  C  CG2 . VAL B 2 87  ? 262.225 278.682 275.952 1.00 36.95  ? 85  VAL B CG2 1 
ATOM   3926  N  N   . LEU B 2 88  ? 263.437 277.554 280.219 1.00 37.37  ? 86  LEU B N   1 
ATOM   3927  C  CA  . LEU B 2 88  ? 263.765 276.781 281.408 1.00 40.25  ? 86  LEU B CA  1 
ATOM   3928  C  C   . LEU B 2 88  ? 263.293 277.448 282.691 1.00 38.32  ? 86  LEU B C   1 
ATOM   3929  O  O   . LEU B 2 88  ? 263.489 276.884 283.772 1.00 42.86  ? 86  LEU B O   1 
ATOM   3930  C  CB  . LEU B 2 88  ? 265.275 276.547 281.481 1.00 40.62  ? 86  LEU B CB  1 
ATOM   3931  C  CG  . LEU B 2 88  ? 265.944 276.075 280.191 1.00 34.72  ? 86  LEU B CG  1 
ATOM   3932  C  CD1 . LEU B 2 88  ? 267.451 276.245 280.280 1.00 29.43  ? 86  LEU B CD1 1 
ATOM   3933  C  CD2 . LEU B 2 88  ? 265.575 274.631 279.905 1.00 33.27  ? 86  LEU B CD2 1 
ATOM   3934  N  N   . TYR B 2 89  ? 262.690 278.630 282.598 1.00 36.24  ? 87  TYR B N   1 
ATOM   3935  C  CA  . TYR B 2 89  ? 262.229 279.381 283.758 1.00 38.44  ? 87  TYR B CA  1 
ATOM   3936  C  C   . TYR B 2 89  ? 260.728 279.277 283.979 1.00 42.87  ? 87  TYR B C   1 
ATOM   3937  O  O   . TYR B 2 89  ? 260.279 279.241 285.127 1.00 43.67  ? 87  TYR B O   1 
ATOM   3938  C  CB  . TYR B 2 89  ? 262.620 280.854 283.611 1.00 36.30  ? 87  TYR B CB  1 
ATOM   3939  C  CG  . TYR B 2 89  ? 262.481 281.661 284.879 1.00 44.48  ? 87  TYR B CG  1 
ATOM   3940  C  CD1 . TYR B 2 89  ? 263.146 281.292 286.041 1.00 43.49  ? 87  TYR B CD1 1 
ATOM   3941  C  CD2 . TYR B 2 89  ? 261.682 282.796 284.913 1.00 43.66  ? 87  TYR B CD2 1 
ATOM   3942  C  CE1 . TYR B 2 89  ? 263.019 282.031 287.199 1.00 42.11  ? 87  TYR B CE1 1 
ATOM   3943  C  CE2 . TYR B 2 89  ? 261.548 283.539 286.065 1.00 43.43  ? 87  TYR B CE2 1 
ATOM   3944  C  CZ  . TYR B 2 89  ? 262.219 283.154 287.205 1.00 45.98  ? 87  TYR B CZ  1 
ATOM   3945  O  OH  . TYR B 2 89  ? 262.087 283.896 288.354 1.00 49.40  ? 87  TYR B OH  1 
ATOM   3946  N  N   . TYR B 2 90  ? 259.946 279.224 282.910 1.00 41.00  ? 88  TYR B N   1 
ATOM   3947  C  CA  . TYR B 2 90  ? 258.494 279.226 283.037 1.00 42.29  ? 88  TYR B CA  1 
ATOM   3948  C  C   . TYR B 2 90  ? 257.999 277.856 283.488 1.00 44.92  ? 88  TYR B C   1 
ATOM   3949  O  O   . TYR B 2 90  ? 258.369 276.842 282.889 1.00 44.92  ? 88  TYR B O   1 
ATOM   3950  C  CB  . TYR B 2 90  ? 257.837 279.604 281.715 1.00 41.95  ? 88  TYR B CB  1 
ATOM   3951  C  CG  . TYR B 2 90  ? 256.347 279.827 281.826 1.00 47.45  ? 88  TYR B CG  1 
ATOM   3952  C  CD1 . TYR B 2 90  ? 255.840 281.016 282.328 1.00 47.02  ? 88  TYR B CD1 1 
ATOM   3953  C  CD2 . TYR B 2 90  ? 255.448 278.846 281.431 1.00 47.98  ? 88  TYR B CD2 1 
ATOM   3954  C  CE1 . TYR B 2 90  ? 254.481 281.223 282.434 1.00 45.90  ? 88  TYR B CE1 1 
ATOM   3955  C  CE2 . TYR B 2 90  ? 254.087 279.045 281.534 1.00 47.57  ? 88  TYR B CE2 1 
ATOM   3956  C  CZ  . TYR B 2 90  ? 253.609 280.235 282.035 1.00 52.11  ? 88  TYR B CZ  1 
ATOM   3957  O  OH  . TYR B 2 90  ? 252.252 280.438 282.139 1.00 56.84  ? 88  TYR B OH  1 
ATOM   3958  N  N   . PRO B 2 91  ? 257.170 277.785 284.535 1.00 48.17  ? 89  PRO B N   1 
ATOM   3959  C  CA  . PRO B 2 91  ? 256.718 278.886 285.393 1.00 44.43  ? 89  PRO B CA  1 
ATOM   3960  C  C   . PRO B 2 91  ? 257.658 279.095 286.572 1.00 45.88  ? 89  PRO B C   1 
ATOM   3961  O  O   . PRO B 2 91  ? 258.237 278.137 287.074 1.00 49.78  ? 89  PRO B O   1 
ATOM   3962  C  CB  . PRO B 2 91  ? 255.318 278.428 285.848 1.00 45.63  ? 89  PRO B CB  1 
ATOM   3963  C  CG  . PRO B 2 91  ? 255.089 277.044 285.245 1.00 47.28  ? 89  PRO B CG  1 
ATOM   3964  C  CD  . PRO B 2 91  ? 256.440 276.547 284.833 1.00 47.15  ? 89  PRO B CD  1 
ATOM   3965  N  N   . PRO B 2 92  ? 257.829 280.333 287.040 1.00 47.66  ? 90  PRO B N   1 
ATOM   3966  C  CA  . PRO B 2 92  ? 258.709 280.552 288.199 1.00 45.42  ? 90  PRO B CA  1 
ATOM   3967  C  C   . PRO B 2 92  ? 258.318 279.721 289.404 1.00 47.04  ? 90  PRO B C   1 
ATOM   3968  O  O   . PRO B 2 92  ? 259.196 279.275 290.153 1.00 48.03  ? 90  PRO B O   1 
ATOM   3969  C  CB  . PRO B 2 92  ? 258.559 282.054 288.470 1.00 43.06  ? 90  PRO B CB  1 
ATOM   3970  C  CG  . PRO B 2 92  ? 258.181 282.633 287.150 1.00 46.22  ? 90  PRO B CG  1 
ATOM   3971  C  CD  . PRO B 2 92  ? 257.332 281.597 286.471 1.00 45.87  ? 90  PRO B CD  1 
ATOM   3972  N  N   . ARG B 2 93  ? 257.027 279.500 289.614 1.00 53.69  ? 91  ARG B N   1 
ATOM   3973  C  CA  . ARG B 2 93  ? 256.537 278.601 290.642 1.00 52.65  ? 91  ARG B CA  1 
ATOM   3974  C  C   . ARG B 2 93  ? 255.509 277.661 290.034 1.00 52.82  ? 91  ARG B C   1 
ATOM   3975  O  O   . ARG B 2 93  ? 254.837 278.015 289.061 1.00 52.98  ? 91  ARG B O   1 
ATOM   3976  C  CB  . ARG B 2 93  ? 255.915 279.372 291.814 1.00 53.20  ? 91  ARG B CB  1 
ATOM   3977  C  CG  . ARG B 2 93  ? 256.920 280.209 292.586 1.00 56.86  ? 91  ARG B CG  1 
ATOM   3978  C  CD  . ARG B 2 93  ? 256.647 280.175 294.079 1.00 65.67  ? 91  ARG B CD  1 
ATOM   3979  N  NE  . ARG B 2 93  ? 257.632 280.937 294.840 1.00 71.21  ? 91  ARG B NE  1 
ATOM   3980  C  CZ  . ARG B 2 93  ? 257.928 282.212 294.628 1.00 71.86  ? 91  ARG B CZ  1 
ATOM   3981  N  NH1 . ARG B 2 93  ? 257.327 282.915 293.681 1.00 69.13  ? 91  ARG B NH1 1 
ATOM   3982  N  NH2 . ARG B 2 93  ? 258.848 282.799 295.388 1.00 65.98  ? 91  ARG B NH2 1 
ATOM   3983  N  N   . PRO B 2 94  ? 255.370 276.457 290.583 1.00 55.16  ? 92  PRO B N   1 
ATOM   3984  C  CA  . PRO B 2 94  ? 254.523 275.447 289.935 1.00 54.24  ? 92  PRO B CA  1 
ATOM   3985  C  C   . PRO B 2 94  ? 253.086 275.927 289.790 1.00 57.95  ? 92  PRO B C   1 
ATOM   3986  O  O   . PRO B 2 94  ? 252.440 276.322 290.763 1.00 56.84  ? 92  PRO B O   1 
ATOM   3987  C  CB  . PRO B 2 94  ? 254.626 274.242 290.877 1.00 57.10  ? 92  PRO B CB  1 
ATOM   3988  C  CG  . PRO B 2 94  ? 255.889 274.460 291.643 1.00 54.10  ? 92  PRO B CG  1 
ATOM   3989  C  CD  . PRO B 2 94  ? 256.027 275.941 291.794 1.00 53.60  ? 92  PRO B CD  1 
ATOM   3990  N  N   . ILE B 2 95  ? 252.589 275.887 288.555 1.00 57.30  ? 93  ILE B N   1 
ATOM   3991  C  CA  . ILE B 2 95  ? 251.200 276.218 288.261 1.00 55.84  ? 93  ILE B CA  1 
ATOM   3992  C  C   . ILE B 2 95  ? 250.451 274.920 287.994 1.00 59.40  ? 93  ILE B C   1 
ATOM   3993  O  O   . ILE B 2 95  ? 250.433 274.421 286.864 1.00 62.45  ? 93  ILE B O   1 
ATOM   3994  C  CB  . ILE B 2 95  ? 251.093 277.182 287.065 1.00 59.20  ? 93  ILE B CB  1 
ATOM   3995  C  CG1 . ILE B 2 95  ? 251.573 278.579 287.459 1.00 56.85  ? 93  ILE B CG1 1 
ATOM   3996  C  CG2 . ILE B 2 95  ? 249.665 277.235 286.543 1.00 59.56  ? 93  ILE B CG2 1 
ATOM   3997  C  CD1 . ILE B 2 95  ? 251.766 279.512 286.284 1.00 52.48  ? 93  ILE B CD1 1 
ATOM   3998  N  N   . GLY B 2 96  ? 249.830 274.365 289.030 1.00 55.97  ? 94  GLY B N   1 
ATOM   3999  C  CA  . GLY B 2 96  ? 249.194 273.070 288.901 1.00 56.87  ? 94  GLY B CA  1 
ATOM   4000  C  C   . GLY B 2 96  ? 250.215 271.974 288.691 1.00 60.56  ? 94  GLY B C   1 
ATOM   4001  O  O   . GLY B 2 96  ? 251.066 271.738 289.554 1.00 61.87  ? 94  GLY B O   1 
ATOM   4002  N  N   . ASP B 2 97  ? 250.146 271.299 287.548 1.00 63.20  ? 95  ASP B N   1 
ATOM   4003  C  CA  . ASP B 2 97  ? 251.128 270.285 287.189 1.00 64.10  ? 95  ASP B CA  1 
ATOM   4004  C  C   . ASP B 2 97  ? 252.272 270.842 286.351 1.00 60.91  ? 95  ASP B C   1 
ATOM   4005  O  O   . ASP B 2 97  ? 253.150 270.076 285.943 1.00 60.81  ? 95  ASP B O   1 
ATOM   4006  C  CB  . ASP B 2 97  ? 250.449 269.137 286.436 1.00 65.59  ? 95  ASP B CB  1 
ATOM   4007  C  CG  . ASP B 2 97  ? 251.164 267.815 286.625 1.00 74.80  ? 95  ASP B CG  1 
ATOM   4008  O  OD1 . ASP B 2 97  ? 252.257 267.812 287.230 1.00 75.45  ? 95  ASP B OD1 1 
ATOM   4009  O  OD2 . ASP B 2 97  ? 250.634 266.779 286.172 1.00 76.27  ? 95  ASP B OD2 1 
ATOM   4010  N  N   . ARG B 2 98  ? 252.285 272.146 286.092 1.00 59.55  ? 96  ARG B N   1 
ATOM   4011  C  CA  . ARG B 2 98  ? 253.329 272.772 285.294 1.00 54.51  ? 96  ARG B CA  1 
ATOM   4012  C  C   . ARG B 2 98  ? 254.482 273.200 286.192 1.00 54.98  ? 96  ARG B C   1 
ATOM   4013  O  O   . ARG B 2 98  ? 254.279 273.926 287.170 1.00 56.08  ? 96  ARG B O   1 
ATOM   4014  C  CB  . ARG B 2 98  ? 252.774 273.978 284.536 1.00 54.14  ? 96  ARG B CB  1 
ATOM   4015  C  CG  . ARG B 2 98  ? 252.871 273.859 283.027 1.00 54.37  ? 96  ARG B CG  1 
ATOM   4016  C  CD  . ARG B 2 98  ? 252.240 275.056 282.342 1.00 55.68  ? 96  ARG B CD  1 
ATOM   4017  N  NE  . ARG B 2 98  ? 252.978 275.453 281.150 1.00 61.26  ? 96  ARG B NE  1 
ATOM   4018  C  CZ  . ARG B 2 98  ? 252.537 276.322 280.250 1.00 61.84  ? 96  ARG B CZ  1 
ATOM   4019  N  NH1 . ARG B 2 98  ? 251.357 276.905 280.374 1.00 57.50  ? 96  ARG B NH1 1 
ATOM   4020  N  NH2 . ARG B 2 98  ? 253.300 276.612 279.201 1.00 58.13  ? 96  ARG B NH2 1 
ATOM   4021  N  N   . LYS B 2 99  ? 255.688 272.748 285.858 1.00 52.04  ? 97  LYS B N   1 
ATOM   4022  C  CA  . LYS B 2 99  ? 256.883 273.055 286.629 1.00 50.21  ? 97  LYS B CA  1 
ATOM   4023  C  C   . LYS B 2 99  ? 258.006 273.477 285.694 1.00 48.75  ? 97  LYS B C   1 
ATOM   4024  O  O   . LYS B 2 99  ? 258.102 273.001 284.560 1.00 54.25  ? 97  LYS B O   1 
ATOM   4025  C  CB  . LYS B 2 99  ? 257.343 271.854 287.465 1.00 48.15  ? 97  LYS B CB  1 
ATOM   4026  C  CG  . LYS B 2 99  ? 256.409 271.478 288.596 1.00 53.06  ? 97  LYS B CG  1 
ATOM   4027  C  CD  . LYS B 2 99  ? 257.117 270.598 289.614 1.00 52.21  ? 97  LYS B CD  1 
ATOM   4028  C  CE  . LYS B 2 99  ? 257.368 269.205 289.062 1.00 54.61  ? 97  LYS B CE  1 
ATOM   4029  N  NZ  . LYS B 2 99  ? 256.224 268.711 288.252 1.00 62.74  ? 97  LYS B NZ  1 
ATOM   4030  N  N   . ASN B 2 100 ? 258.858 274.373 286.183 1.00 47.07  ? 98  ASN B N   1 
ATOM   4031  C  CA  . ASN B 2 100 ? 260.057 274.742 285.449 1.00 44.10  ? 98  ASN B CA  1 
ATOM   4032  C  C   . ASN B 2 100 ? 261.154 273.710 285.709 1.00 42.96  ? 98  ASN B C   1 
ATOM   4033  O  O   . ASN B 2 100 ? 260.978 272.755 286.469 1.00 44.04  ? 98  ASN B O   1 
ATOM   4034  C  CB  . ASN B 2 100 ? 260.487 276.165 285.807 1.00 39.44  ? 98  ASN B CB  1 
ATOM   4035  C  CG  . ASN B 2 100 ? 261.061 276.281 287.207 1.00 40.66  ? 98  ASN B CG  1 
ATOM   4036  O  OD1 . ASN B 2 100 ? 261.143 275.304 287.948 1.00 44.28  ? 98  ASN B OD1 1 
ATOM   4037  N  ND2 . ASN B 2 100 ? 261.461 277.491 287.575 1.00 40.41  ? 98  ASN B ND2 1 
ATOM   4038  N  N   . LEU B 2 101 ? 262.305 273.898 285.060 1.00 43.64  ? 99  LEU B N   1 
ATOM   4039  C  CA  . LEU B 2 101 ? 263.347 272.876 285.100 1.00 40.27  ? 99  LEU B CA  1 
ATOM   4040  C  C   . LEU B 2 101 ? 263.820 272.608 286.525 1.00 38.96  ? 99  LEU B C   1 
ATOM   4041  O  O   . LEU B 2 101 ? 263.968 271.447 286.931 1.00 42.37  ? 99  LEU B O   1 
ATOM   4042  C  CB  . LEU B 2 101 ? 264.520 273.292 284.213 1.00 36.29  ? 99  LEU B CB  1 
ATOM   4043  C  CG  . LEU B 2 101 ? 265.721 272.348 284.187 1.00 37.43  ? 99  LEU B CG  1 
ATOM   4044  C  CD1 . LEU B 2 101 ? 265.272 270.920 283.934 1.00 35.27  ? 99  LEU B CD1 1 
ATOM   4045  C  CD2 . LEU B 2 101 ? 266.722 272.789 283.134 1.00 35.44  ? 99  LEU B CD2 1 
ATOM   4046  N  N   . PHE B 2 102 ? 264.059 273.664 287.304 1.00 36.72  ? 100 PHE B N   1 
ATOM   4047  C  CA  . PHE B 2 102 ? 264.567 273.452 288.654 1.00 39.75  ? 100 PHE B CA  1 
ATOM   4048  C  C   . PHE B 2 102 ? 263.531 272.790 289.549 1.00 42.12  ? 100 PHE B C   1 
ATOM   4049  O  O   . PHE B 2 102 ? 263.896 272.014 290.437 1.00 41.44  ? 100 PHE B O   1 
ATOM   4050  C  CB  . PHE B 2 102 ? 265.033 274.764 289.279 1.00 37.42  ? 100 PHE B CB  1 
ATOM   4051  C  CG  . PHE B 2 102 ? 265.672 274.583 290.624 1.00 41.88  ? 100 PHE B CG  1 
ATOM   4052  C  CD1 . PHE B 2 102 ? 266.928 274.012 290.735 1.00 39.47  ? 100 PHE B CD1 1 
ATOM   4053  C  CD2 . PHE B 2 102 ? 265.008 274.958 291.778 1.00 43.62  ? 100 PHE B CD2 1 
ATOM   4054  C  CE1 . PHE B 2 102 ? 267.515 273.834 291.970 1.00 36.18  ? 100 PHE B CE1 1 
ATOM   4055  C  CE2 . PHE B 2 102 ? 265.591 274.784 293.014 1.00 42.22  ? 100 PHE B CE2 1 
ATOM   4056  C  CZ  . PHE B 2 102 ? 266.846 274.220 293.111 1.00 39.53  ? 100 PHE B CZ  1 
ATOM   4057  N  N   . SER B 2 103 ? 262.247 273.089 289.353 1.00 43.91  ? 101 SER B N   1 
ATOM   4058  C  CA  . SER B 2 103 ? 261.219 272.393 290.119 1.00 40.73  ? 101 SER B CA  1 
ATOM   4059  C  C   . SER B 2 103 ? 261.262 270.897 289.844 1.00 46.22  ? 101 SER B C   1 
ATOM   4060  O  O   . SER B 2 103 ? 261.178 270.083 290.771 1.00 48.84  ? 101 SER B O   1 
ATOM   4061  C  CB  . SER B 2 103 ? 259.840 272.961 289.789 1.00 43.41  ? 101 SER B CB  1 
ATOM   4062  O  OG  . SER B 2 103 ? 259.538 274.080 290.601 1.00 46.26  ? 101 SER B OG  1 
ATOM   4063  N  N   . THR B 2 104 ? 261.404 270.518 288.573 1.00 43.57  ? 102 THR B N   1 
ATOM   4064  C  CA  . THR B 2 104 ? 261.514 269.106 288.228 1.00 40.30  ? 102 THR B CA  1 
ATOM   4065  C  C   . THR B 2 104 ? 262.752 268.480 288.854 1.00 43.65  ? 102 THR B C   1 
ATOM   4066  O  O   . THR B 2 104 ? 262.692 267.365 289.384 1.00 49.59  ? 102 THR B O   1 
ATOM   4067  C  CB  . THR B 2 104 ? 261.542 268.939 286.710 1.00 40.75  ? 102 THR B CB  1 
ATOM   4068  O  OG1 . THR B 2 104 ? 260.425 269.626 286.132 1.00 46.53  ? 102 THR B OG1 1 
ATOM   4069  C  CG2 . THR B 2 104 ? 261.482 267.469 286.333 1.00 44.02  ? 102 THR B CG2 1 
ATOM   4070  N  N   . ILE B 2 105 ? 263.886 269.182 288.805 1.00 43.39  ? 103 ILE B N   1 
ATOM   4071  C  CA  . ILE B 2 105 ? 265.119 268.642 289.376 1.00 44.18  ? 103 ILE B CA  1 
ATOM   4072  C  C   . ILE B 2 105 ? 264.964 268.436 290.879 1.00 47.49  ? 103 ILE B C   1 
ATOM   4073  O  O   . ILE B 2 105 ? 265.340 267.392 291.427 1.00 51.54  ? 103 ILE B O   1 
ATOM   4074  C  CB  . ILE B 2 105 ? 266.308 269.564 289.054 1.00 41.58  ? 103 ILE B CB  1 
ATOM   4075  C  CG1 . ILE B 2 105 ? 266.624 269.528 287.559 1.00 39.07  ? 103 ILE B CG1 1 
ATOM   4076  C  CG2 . ILE B 2 105 ? 267.525 269.173 289.873 1.00 42.96  ? 103 ILE B CG2 1 
ATOM   4077  C  CD1 . ILE B 2 105 ? 267.422 270.718 287.078 1.00 36.43  ? 103 ILE B CD1 1 
ATOM   4078  N  N   . PHE B 2 106 ? 264.416 269.438 291.570 1.00 46.46  ? 104 PHE B N   1 
ATOM   4079  C  CA  . PHE B 2 106 ? 264.236 269.343 293.014 1.00 48.24  ? 104 PHE B CA  1 
ATOM   4080  C  C   . PHE B 2 106 ? 263.275 268.218 293.376 1.00 53.80  ? 104 PHE B C   1 
ATOM   4081  O  O   . PHE B 2 106 ? 263.509 267.479 294.338 1.00 56.37  ? 104 PHE B O   1 
ATOM   4082  C  CB  . PHE B 2 106 ? 263.735 270.678 293.563 1.00 49.09  ? 104 PHE B CB  1 
ATOM   4083  C  CG  . PHE B 2 106 ? 263.910 270.831 295.047 1.00 56.01  ? 104 PHE B CG  1 
ATOM   4084  C  CD1 . PHE B 2 106 ? 263.016 270.248 295.928 1.00 53.35  ? 104 PHE B CD1 1 
ATOM   4085  C  CD2 . PHE B 2 106 ? 264.960 271.572 295.558 1.00 54.06  ? 104 PHE B CD2 1 
ATOM   4086  C  CE1 . PHE B 2 106 ? 263.174 270.393 297.290 1.00 56.77  ? 104 PHE B CE1 1 
ATOM   4087  C  CE2 . PHE B 2 106 ? 265.120 271.722 296.920 1.00 56.46  ? 104 PHE B CE2 1 
ATOM   4088  C  CZ  . PHE B 2 106 ? 264.227 271.131 297.786 1.00 57.65  ? 104 PHE B CZ  1 
ATOM   4089  N  N   . GLY B 2 107 ? 262.181 268.079 292.624 1.00 49.27  ? 105 GLY B N   1 
ATOM   4090  C  CA  . GLY B 2 107 ? 261.259 266.987 292.882 1.00 48.04  ? 105 GLY B CA  1 
ATOM   4091  C  C   . GLY B 2 107 ? 261.893 265.628 292.660 1.00 54.96  ? 105 GLY B C   1 
ATOM   4092  O  O   . GLY B 2 107 ? 261.668 264.693 293.432 1.00 62.33  ? 105 GLY B O   1 
ATOM   4093  N  N   . LEU B 2 108 ? 262.696 265.500 291.602 1.00 51.26  ? 106 LEU B N   1 
ATOM   4094  C  CA  . LEU B 2 108 ? 263.380 264.239 291.340 1.00 49.71  ? 106 LEU B CA  1 
ATOM   4095  C  C   . LEU B 2 108 ? 264.374 263.913 292.447 1.00 53.09  ? 106 LEU B C   1 
ATOM   4096  O  O   . LEU B 2 108 ? 264.548 262.745 292.813 1.00 56.78  ? 106 LEU B O   1 
ATOM   4097  C  CB  . LEU B 2 108 ? 264.081 264.301 289.984 1.00 50.26  ? 106 LEU B CB  1 
ATOM   4098  C  CG  . LEU B 2 108 ? 263.175 264.160 288.761 1.00 48.62  ? 106 LEU B CG  1 
ATOM   4099  C  CD1 . LEU B 2 108 ? 263.927 264.515 287.490 1.00 46.78  ? 106 LEU B CD1 1 
ATOM   4100  C  CD2 . LEU B 2 108 ? 262.608 262.755 288.678 1.00 49.49  ? 106 LEU B CD2 1 
ATOM   4101  N  N   . ILE B 2 109 ? 265.048 264.933 292.982 1.00 55.33  ? 107 ILE B N   1 
ATOM   4102  C  CA  . ILE B 2 109 ? 265.967 264.704 294.092 1.00 57.87  ? 107 ILE B CA  1 
ATOM   4103  C  C   . ILE B 2 109 ? 265.209 264.363 295.367 1.00 61.50  ? 107 ILE B C   1 
ATOM   4104  O  O   . ILE B 2 109 ? 265.726 263.643 296.229 1.00 64.92  ? 107 ILE B O   1 
ATOM   4105  C  CB  . ILE B 2 109 ? 266.886 265.920 294.297 1.00 59.60  ? 107 ILE B CB  1 
ATOM   4106  C  CG1 . ILE B 2 109 ? 267.752 266.150 293.059 1.00 53.17  ? 107 ILE B CG1 1 
ATOM   4107  C  CG2 . ILE B 2 109 ? 267.762 265.716 295.520 1.00 55.52  ? 107 ILE B CG2 1 
ATOM   4108  C  CD1 . ILE B 2 109 ? 268.683 267.331 293.184 1.00 47.25  ? 107 ILE B CD1 1 
ATOM   4109  N  N   . ASN B 2 110 ? 263.992 264.887 295.532 1.00 65.55  ? 108 ASN B N   1 
ATOM   4110  C  CA  . ASN B 2 110 ? 263.193 264.514 296.694 1.00 68.55  ? 108 ASN B CA  1 
ATOM   4111  C  C   . ASN B 2 110 ? 262.849 263.033 296.669 1.00 71.55  ? 108 ASN B C   1 
ATOM   4112  O  O   . ASN B 2 110 ? 262.717 262.407 297.727 1.00 73.46  ? 108 ASN B O   1 
ATOM   4113  C  CB  . ASN B 2 110 ? 261.923 265.361 296.764 1.00 66.79  ? 108 ASN B CB  1 
ATOM   4114  C  CG  . ASN B 2 110 ? 261.634 265.855 298.166 1.00 73.17  ? 108 ASN B CG  1 
ATOM   4115  O  OD1 . ASN B 2 110 ? 262.417 265.626 299.089 1.00 73.09  ? 108 ASN B OD1 1 
ATOM   4116  N  ND2 . ASN B 2 110 ? 260.506 266.533 298.335 1.00 75.83  ? 108 ASN B ND2 1 
ATOM   4117  N  N   . SER B 2 111 ? 262.687 262.462 295.481 1.00 68.02  ? 109 SER B N   1 
ATOM   4118  C  CA  . SER B 2 111 ? 262.713 261.018 295.313 1.00 68.18  ? 109 SER B CA  1 
ATOM   4119  C  C   . SER B 2 111 ? 264.175 260.579 295.268 1.00 69.76  ? 109 SER B C   1 
ATOM   4120  O  O   . SER B 2 111 ? 265.088 261.353 295.566 1.00 72.13  ? 109 SER B O   1 
ATOM   4121  C  CB  . SER B 2 111 ? 261.945 260.608 294.059 1.00 65.52  ? 109 SER B CB  1 
ATOM   4122  O  OG  . SER B 2 111 ? 260.832 261.455 293.840 1.00 68.66  ? 109 SER B OG  1 
ATOM   4123  N  N   . ASN B 2 112 ? 264.422 259.331 294.898 1.00 68.73  ? 110 ASN B N   1 
ATOM   4124  C  CA  . ASN B 2 112 ? 265.776 258.843 294.679 1.00 68.89  ? 110 ASN B CA  1 
ATOM   4125  C  C   . ASN B 2 112 ? 265.972 258.483 293.213 1.00 69.98  ? 110 ASN B C   1 
ATOM   4126  O  O   . ASN B 2 112 ? 266.627 257.497 292.871 1.00 76.95  ? 110 ASN B O   1 
ATOM   4127  C  CB  . ASN B 2 112 ? 266.084 257.656 295.586 1.00 76.14  ? 110 ASN B CB  1 
ATOM   4128  C  CG  . ASN B 2 112 ? 266.256 258.064 297.035 1.00 81.74  ? 110 ASN B CG  1 
ATOM   4129  O  OD1 . ASN B 2 112 ? 265.279 258.298 297.745 1.00 81.28  ? 110 ASN B OD1 1 
ATOM   4130  N  ND2 . ASN B 2 112 ? 267.504 258.159 297.480 1.00 82.56  ? 110 ASN B ND2 1 
ATOM   4131  N  N   . SER B 2 113 ? 265.395 259.295 292.328 1.00 62.95  ? 111 SER B N   1 
ATOM   4132  C  CA  . SER B 2 113 ? 265.420 259.052 290.894 1.00 64.44  ? 111 SER B CA  1 
ATOM   4133  C  C   . SER B 2 113 ? 266.428 259.927 290.159 1.00 65.39  ? 111 SER B C   1 
ATOM   4134  O  O   . SER B 2 113 ? 266.425 259.948 288.924 1.00 68.69  ? 111 SER B O   1 
ATOM   4135  C  CB  . SER B 2 113 ? 264.022 259.259 290.308 1.00 63.12  ? 111 SER B CB  1 
ATOM   4136  O  OG  . SER B 2 113 ? 263.362 260.343 290.937 1.00 65.62  ? 111 SER B OG  1 
ATOM   4137  N  N   . LEU B 2 114 ? 267.287 260.646 290.878 1.00 64.55  ? 112 LEU B N   1 
ATOM   4138  C  CA  . LEU B 2 114 ? 268.288 261.486 290.232 1.00 62.15  ? 112 LEU B CA  1 
ATOM   4139  C  C   . LEU B 2 114 ? 269.455 261.697 291.183 1.00 62.91  ? 112 LEU B C   1 
ATOM   4140  O  O   . LEU B 2 114 ? 269.251 262.065 292.343 1.00 65.05  ? 112 LEU B O   1 
ATOM   4141  C  CB  . LEU B 2 114 ? 267.696 262.835 289.810 1.00 60.28  ? 112 LEU B CB  1 
ATOM   4142  C  CG  . LEU B 2 114 ? 268.648 263.761 289.052 1.00 57.42  ? 112 LEU B CG  1 
ATOM   4143  C  CD1 . LEU B 2 114 ? 268.655 263.421 287.574 1.00 50.38  ? 112 LEU B CD1 1 
ATOM   4144  C  CD2 . LEU B 2 114 ? 268.272 265.220 289.264 1.00 51.99  ? 112 LEU B CD2 1 
ATOM   4145  N  N   . ASP B 2 115 ? 270.668 261.469 290.688 1.00 61.15  ? 113 ASP B N   1 
ATOM   4146  C  CA  . ASP B 2 115 ? 271.888 261.665 291.457 1.00 59.71  ? 113 ASP B CA  1 
ATOM   4147  C  C   . ASP B 2 115 ? 272.587 262.931 290.982 1.00 56.14  ? 113 ASP B C   1 
ATOM   4148  O  O   . ASP B 2 115 ? 272.843 263.092 289.784 1.00 54.20  ? 113 ASP B O   1 
ATOM   4149  C  CB  . ASP B 2 115 ? 272.820 260.459 291.321 1.00 63.49  ? 113 ASP B CB  1 
ATOM   4150  C  CG  . ASP B 2 115 ? 272.504 259.362 292.320 1.00 78.53  ? 113 ASP B CG  1 
ATOM   4151  O  OD1 . ASP B 2 115 ? 271.745 259.625 293.276 1.00 77.33  ? 113 ASP B OD1 1 
ATOM   4152  O  OD2 . ASP B 2 115 ? 273.013 258.234 292.148 1.00 81.78  ? 113 ASP B OD2 1 
ATOM   4153  N  N   . VAL B 2 116 ? 272.894 263.822 291.923 1.00 54.12  ? 114 VAL B N   1 
ATOM   4154  C  CA  . VAL B 2 116 ? 273.590 265.068 291.635 1.00 49.27  ? 114 VAL B CA  1 
ATOM   4155  C  C   . VAL B 2 116 ? 274.843 265.127 292.497 1.00 47.88  ? 114 VAL B C   1 
ATOM   4156  O  O   . VAL B 2 116 ? 274.930 264.501 293.556 1.00 56.98  ? 114 VAL B O   1 
ATOM   4157  C  CB  . VAL B 2 116 ? 272.704 266.309 291.871 1.00 47.27  ? 114 VAL B CB  1 
ATOM   4158  C  CG1 . VAL B 2 116 ? 271.544 266.325 290.889 1.00 45.06  ? 114 VAL B CG1 1 
ATOM   4159  C  CG2 . VAL B 2 116 ? 272.197 266.338 293.302 1.00 42.90  ? 114 VAL B CG2 1 
ATOM   4160  N  N   . TYR B 2 117 ? 275.822 265.897 292.029 1.00 46.77  ? 115 TYR B N   1 
ATOM   4161  C  CA  . TYR B 2 117 ? 277.147 265.917 292.628 1.00 51.40  ? 115 TYR B CA  1 
ATOM   4162  C  C   . TYR B 2 117 ? 277.544 267.343 292.980 1.00 50.02  ? 115 TYR B C   1 
ATOM   4163  O  O   . TYR B 2 117 ? 277.084 268.305 292.359 1.00 50.26  ? 115 TYR B O   1 
ATOM   4164  C  CB  . TYR B 2 117 ? 278.177 265.291 291.685 1.00 50.80  ? 115 TYR B CB  1 
ATOM   4165  C  CG  . TYR B 2 117 ? 277.738 263.949 291.146 1.00 53.36  ? 115 TYR B CG  1 
ATOM   4166  C  CD1 . TYR B 2 117 ? 276.975 263.861 289.991 1.00 54.02  ? 115 TYR B CD1 1 
ATOM   4167  C  CD2 . TYR B 2 117 ? 278.072 262.772 291.800 1.00 55.99  ? 115 TYR B CD2 1 
ATOM   4168  C  CE1 . TYR B 2 117 ? 276.564 262.642 289.497 1.00 54.22  ? 115 TYR B CE1 1 
ATOM   4169  C  CE2 . TYR B 2 117 ? 277.665 261.547 291.312 1.00 59.35  ? 115 TYR B CE2 1 
ATOM   4170  C  CZ  . TYR B 2 117 ? 276.911 261.488 290.160 1.00 57.84  ? 115 TYR B CZ  1 
ATOM   4171  O  OH  . TYR B 2 117 ? 276.503 260.271 289.667 1.00 61.59  ? 115 TYR B OH  1 
ATOM   4172  N  N   . GLU B 2 118 ? 278.407 267.465 293.985 1.00 53.16  ? 116 GLU B N   1 
ATOM   4173  C  CA  . GLU B 2 118 ? 278.786 268.775 294.496 1.00 54.99  ? 116 GLU B CA  1 
ATOM   4174  C  C   . GLU B 2 118 ? 279.488 269.596 293.423 1.00 50.26  ? 116 GLU B C   1 
ATOM   4175  O  O   . GLU B 2 118 ? 280.248 269.067 292.608 1.00 49.46  ? 116 GLU B O   1 
ATOM   4176  C  CB  . GLU B 2 118 ? 279.698 268.625 295.714 1.00 54.67  ? 116 GLU B CB  1 
ATOM   4177  C  CG  . GLU B 2 118 ? 279.403 267.402 296.562 1.00 67.01  ? 116 GLU B CG  1 
ATOM   4178  C  CD  . GLU B 2 118 ? 279.674 267.634 298.034 1.00 76.98  ? 116 GLU B CD  1 
ATOM   4179  O  OE1 . GLU B 2 118 ? 280.255 268.685 298.376 1.00 78.94  ? 116 GLU B OE1 1 
ATOM   4180  O  OE2 . GLU B 2 118 ? 279.308 266.763 298.851 1.00 76.35  ? 116 GLU B OE2 1 
ATOM   4181  N  N   . TYR B 2 119 ? 279.229 270.900 293.429 1.00 48.59  ? 117 TYR B N   1 
ATOM   4182  C  CA  . TYR B 2 119 ? 279.902 271.833 292.534 1.00 47.45  ? 117 TYR B CA  1 
ATOM   4183  C  C   . TYR B 2 119 ? 281.217 272.257 293.178 1.00 55.91  ? 117 TYR B C   1 
ATOM   4184  O  O   . TYR B 2 119 ? 281.227 273.058 294.117 1.00 59.48  ? 117 TYR B O   1 
ATOM   4185  C  CB  . TYR B 2 119 ? 279.020 273.044 292.243 1.00 45.62  ? 117 TYR B CB  1 
ATOM   4186  C  CG  . TYR B 2 119 ? 279.722 274.131 291.459 1.00 47.22  ? 117 TYR B CG  1 
ATOM   4187  C  CD1 . TYR B 2 119 ? 279.724 274.123 290.073 1.00 47.83  ? 117 TYR B CD1 1 
ATOM   4188  C  CD2 . TYR B 2 119 ? 280.384 275.164 292.108 1.00 45.85  ? 117 TYR B CD2 1 
ATOM   4189  C  CE1 . TYR B 2 119 ? 280.365 275.112 289.354 1.00 50.09  ? 117 TYR B CE1 1 
ATOM   4190  C  CE2 . TYR B 2 119 ? 281.027 276.156 291.399 1.00 49.95  ? 117 TYR B CE2 1 
ATOM   4191  C  CZ  . TYR B 2 119 ? 281.015 276.126 290.022 1.00 52.39  ? 117 TYR B CZ  1 
ATOM   4192  O  OH  . TYR B 2 119 ? 281.653 277.113 289.309 1.00 50.19  ? 117 TYR B OH  1 
ATOM   4193  N  N   . LEU B 2 120 ? 282.321 271.721 292.674 1.00 56.47  ? 118 LEU B N   1 
ATOM   4194  C  CA  . LEU B 2 120 ? 283.650 272.089 293.133 1.00 57.84  ? 118 LEU B CA  1 
ATOM   4195  C  C   . LEU B 2 120 ? 284.273 273.087 292.167 1.00 64.54  ? 118 LEU B C   1 
ATOM   4196  O  O   . LEU B 2 120 ? 283.992 273.075 290.966 1.00 63.80  ? 118 LEU B O   1 
ATOM   4197  C  CB  . LEU B 2 120 ? 284.545 270.856 293.263 1.00 55.93  ? 118 LEU B CB  1 
ATOM   4198  C  CG  . LEU B 2 120 ? 283.919 269.644 293.952 1.00 59.49  ? 118 LEU B CG  1 
ATOM   4199  C  CD1 . LEU B 2 120 ? 284.477 268.355 293.374 1.00 62.10  ? 118 LEU B CD1 1 
ATOM   4200  C  CD2 . LEU B 2 120 ? 284.142 269.705 295.454 1.00 56.28  ? 118 LEU B CD2 1 
ATOM   4201  N  N   . ASP B 2 121 ? 285.125 273.954 292.703 1.00 67.61  ? 119 ASP B N   1 
ATOM   4202  C  CA  . ASP B 2 121 ? 285.765 274.996 291.912 1.00 72.44  ? 119 ASP B CA  1 
ATOM   4203  C  C   . ASP B 2 121 ? 287.017 274.430 291.252 1.00 72.75  ? 119 ASP B C   1 
ATOM   4204  O  O   . ASP B 2 121 ? 287.959 274.024 291.941 1.00 73.38  ? 119 ASP B O   1 
ATOM   4205  C  CB  . ASP B 2 121 ? 286.115 276.199 292.786 1.00 75.69  ? 119 ASP B CB  1 
ATOM   4206  C  CG  . ASP B 2 121 ? 286.122 277.501 292.010 1.00 81.69  ? 119 ASP B CG  1 
ATOM   4207  O  OD1 . ASP B 2 121 ? 285.252 277.675 291.131 1.00 77.03  ? 119 ASP B OD1 1 
ATOM   4208  O  OD2 . ASP B 2 121 ? 286.998 278.350 292.279 1.00 83.69  ? 119 ASP B OD2 1 
ATOM   4209  N  N   . GLY B 2 122 ? 287.023 274.402 289.922 1.00 66.71  ? 120 GLY B N   1 
ATOM   4210  C  CA  . GLY B 2 122 ? 288.184 273.942 289.188 1.00 62.03  ? 120 GLY B CA  1 
ATOM   4211  C  C   . GLY B 2 122 ? 287.947 272.705 288.346 1.00 62.53  ? 120 GLY B C   1 
ATOM   4212  O  O   . GLY B 2 122 ? 288.473 272.602 287.234 1.00 64.61  ? 120 GLY B O   1 
ATOM   4213  N  N   . PHE B 2 123 ? 287.159 271.761 288.855 1.00 59.31  ? 121 PHE B N   1 
ATOM   4214  C  CA  . PHE B 2 123 ? 286.962 270.494 288.167 1.00 57.40  ? 121 PHE B CA  1 
ATOM   4215  C  C   . PHE B 2 123 ? 285.613 269.905 288.550 1.00 60.65  ? 121 PHE B C   1 
ATOM   4216  O  O   . PHE B 2 123 ? 284.995 270.305 289.540 1.00 60.85  ? 121 PHE B O   1 
ATOM   4217  C  CB  . PHE B 2 123 ? 288.082 269.499 288.494 1.00 57.65  ? 121 PHE B CB  1 
ATOM   4218  C  CG  . PHE B 2 123 ? 288.039 268.983 289.905 1.00 61.82  ? 121 PHE B CG  1 
ATOM   4219  C  CD1 . PHE B 2 123 ? 288.272 269.831 290.975 1.00 58.83  ? 121 PHE B CD1 1 
ATOM   4220  C  CD2 . PHE B 2 123 ? 287.763 267.652 290.160 1.00 60.48  ? 121 PHE B CD2 1 
ATOM   4221  C  CE1 . PHE B 2 123 ? 288.229 269.361 292.271 1.00 57.86  ? 121 PHE B CE1 1 
ATOM   4222  C  CE2 . PHE B 2 123 ? 287.721 267.175 291.455 1.00 63.79  ? 121 PHE B CE2 1 
ATOM   4223  C  CZ  . PHE B 2 123 ? 287.955 268.031 292.511 1.00 63.34  ? 121 PHE B CZ  1 
ATOM   4224  N  N   . GLU B 2 124 ? 285.163 268.945 287.746 1.00 61.38  ? 122 GLU B N   1 
ATOM   4225  C  CA  . GLU B 2 124 ? 283.933 268.205 287.994 1.00 60.55  ? 122 GLU B CA  1 
ATOM   4226  C  C   . GLU B 2 124 ? 284.266 266.727 288.140 1.00 61.69  ? 122 GLU B C   1 
ATOM   4227  O  O   . GLU B 2 124 ? 284.984 266.165 287.308 1.00 62.55  ? 122 GLU B O   1 
ATOM   4228  C  CB  . GLU B 2 124 ? 282.921 268.409 286.862 1.00 54.60  ? 122 GLU B CB  1 
ATOM   4229  C  CG  . GLU B 2 124 ? 282.502 269.852 286.638 1.00 51.02  ? 122 GLU B CG  1 
ATOM   4230  C  CD  . GLU B 2 124 ? 283.526 270.642 285.848 1.00 55.11  ? 122 GLU B CD  1 
ATOM   4231  O  OE1 . GLU B 2 124 ? 284.083 270.089 284.878 1.00 55.12  ? 122 GLU B OE1 1 
ATOM   4232  O  OE2 . GLU B 2 124 ? 283.773 271.815 286.195 1.00 56.85  ? 122 GLU B OE2 1 
ATOM   4233  N  N   . ALA B 2 125 ? 283.744 266.103 289.193 1.00 62.88  ? 123 ALA B N   1 
ATOM   4234  C  CA  . ALA B 2 125 ? 283.973 264.683 289.449 1.00 63.66  ? 123 ALA B CA  1 
ATOM   4235  C  C   . ALA B 2 125 ? 282.643 264.045 289.822 1.00 62.10  ? 123 ALA B C   1 
ATOM   4236  O  O   . ALA B 2 125 ? 282.137 264.265 290.927 1.00 64.73  ? 123 ALA B O   1 
ATOM   4237  C  CB  . ALA B 2 125 ? 285.008 264.479 290.556 1.00 66.76  ? 123 ALA B CB  1 
ATOM   4238  N  N   . PHE B 2 126 ? 282.080 263.260 288.908 1.00 58.80  ? 124 PHE B N   1 
ATOM   4239  C  CA  . PHE B 2 126 ? 280.796 262.601 289.137 1.00 62.50  ? 124 PHE B CA  1 
ATOM   4240  C  C   . PHE B 2 126 ? 281.028 261.168 289.614 1.00 64.82  ? 124 PHE B C   1 
ATOM   4241  O  O   . PHE B 2 126 ? 280.763 260.187 288.918 1.00 65.54  ? 124 PHE B O   1 
ATOM   4242  C  CB  . PHE B 2 126 ? 279.942 262.644 287.873 1.00 56.06  ? 124 PHE B CB  1 
ATOM   4243  C  CG  . PHE B 2 126 ? 279.827 264.012 287.263 1.00 53.09  ? 124 PHE B CG  1 
ATOM   4244  C  CD1 . PHE B 2 126 ? 279.905 265.146 288.051 1.00 54.36  ? 124 PHE B CD1 1 
ATOM   4245  C  CD2 . PHE B 2 126 ? 279.635 264.161 285.902 1.00 52.89  ? 124 PHE B CD2 1 
ATOM   4246  C  CE1 . PHE B 2 126 ? 279.799 266.401 287.493 1.00 54.43  ? 124 PHE B CE1 1 
ATOM   4247  C  CE2 . PHE B 2 126 ? 279.528 265.415 285.338 1.00 52.07  ? 124 PHE B CE2 1 
ATOM   4248  C  CZ  . PHE B 2 126 ? 279.611 266.536 286.135 1.00 54.58  ? 124 PHE B CZ  1 
ATOM   4249  N  N   . THR B 2 127 ? 281.537 261.067 290.838 1.00 70.05  ? 125 THR B N   1 
ATOM   4250  C  CA  . THR B 2 127 ? 281.803 259.791 291.481 1.00 68.79  ? 125 THR B CA  1 
ATOM   4251  C  C   . THR B 2 127 ? 281.086 259.739 292.824 1.00 70.62  ? 125 THR B C   1 
ATOM   4252  O  O   . THR B 2 127 ? 280.673 260.764 293.371 1.00 71.07  ? 125 THR B O   1 
ATOM   4253  C  CB  . THR B 2 127 ? 283.306 259.562 291.679 1.00 70.07  ? 125 THR B CB  1 
ATOM   4254  O  OG1 . THR B 2 127 ? 283.834 260.568 292.552 1.00 72.54  ? 125 THR B OG1 1 
ATOM   4255  C  CG2 . THR B 2 127 ? 284.034 259.623 290.346 1.00 61.73  ? 125 THR B CG2 1 
ATOM   4256  N  N   . ASP B 2 128 ? 280.950 258.523 293.356 1.00 74.21  ? 126 ASP B N   1 
ATOM   4257  C  CA  . ASP B 2 128 ? 280.207 258.332 294.597 1.00 72.95  ? 126 ASP B CA  1 
ATOM   4258  C  C   . ASP B 2 128 ? 280.796 259.128 295.752 1.00 70.80  ? 126 ASP B C   1 
ATOM   4259  O  O   . ASP B 2 128 ? 280.088 259.400 296.728 1.00 74.78  ? 126 ASP B O   1 
ATOM   4260  C  CB  . ASP B 2 128 ? 280.164 256.848 294.956 1.00 75.46  ? 126 ASP B CB  1 
ATOM   4261  C  CG  . ASP B 2 128 ? 279.646 255.990 293.821 1.00 86.50  ? 126 ASP B CG  1 
ATOM   4262  O  OD1 . ASP B 2 128 ? 278.500 256.218 293.379 1.00 87.79  ? 126 ASP B OD1 1 
ATOM   4263  O  OD2 . ASP B 2 128 ? 280.386 255.093 293.365 1.00 88.41  ? 126 ASP B OD2 1 
ATOM   4264  N  N   . GLN B 2 129 ? 282.072 259.504 295.671 1.00 70.12  ? 127 GLN B N   1 
ATOM   4265  C  CA  . GLN B 2 129 ? 282.656 260.339 296.714 1.00 71.23  ? 127 GLN B CA  1 
ATOM   4266  C  C   . GLN B 2 129 ? 281.966 261.694 296.783 1.00 73.13  ? 127 GLN B C   1 
ATOM   4267  O  O   . GLN B 2 129 ? 281.705 262.212 297.875 1.00 71.28  ? 127 GLN B O   1 
ATOM   4268  C  CB  . GLN B 2 129 ? 284.154 260.515 296.467 1.00 72.89  ? 127 GLN B CB  1 
ATOM   4269  C  CG  . GLN B 2 129 ? 284.685 261.875 296.882 1.00 75.81  ? 127 GLN B CG  1 
ATOM   4270  C  CD  . GLN B 2 129 ? 286.197 261.919 296.928 1.00 80.33  ? 127 GLN B CD  1 
ATOM   4271  O  OE1 . GLN B 2 129 ? 286.873 261.292 296.113 1.00 80.93  ? 127 GLN B OE1 1 
ATOM   4272  N  NE2 . GLN B 2 129 ? 286.738 262.658 297.889 1.00 82.12  ? 127 GLN B NE2 1 
ATOM   4273  N  N   . TYR B 2 130 ? 281.660 262.282 295.629 1.00 72.94  ? 128 TYR B N   1 
ATOM   4274  C  CA  . TYR B 2 130 ? 281.100 263.624 295.554 1.00 67.45  ? 128 TYR B CA  1 
ATOM   4275  C  C   . TYR B 2 130 ? 279.583 263.640 295.432 1.00 64.63  ? 128 TYR B C   1 
ATOM   4276  O  O   . TYR B 2 130 ? 279.004 264.718 295.269 1.00 61.86  ? 128 TYR B O   1 
ATOM   4277  C  CB  . TYR B 2 130 ? 281.721 264.385 294.380 1.00 62.92  ? 128 TYR B CB  1 
ATOM   4278  C  CG  . TYR B 2 130 ? 283.152 264.802 294.622 1.00 67.54  ? 128 TYR B CG  1 
ATOM   4279  C  CD1 . TYR B 2 130 ? 283.464 265.750 295.586 1.00 68.27  ? 128 TYR B CD1 1 
ATOM   4280  C  CD2 . TYR B 2 130 ? 284.192 264.244 293.892 1.00 69.28  ? 128 TYR B CD2 1 
ATOM   4281  C  CE1 . TYR B 2 130 ? 284.769 266.134 295.814 1.00 69.92  ? 128 TYR B CE1 1 
ATOM   4282  C  CE2 . TYR B 2 130 ? 285.501 264.621 294.113 1.00 71.34  ? 128 TYR B CE2 1 
ATOM   4283  C  CZ  . TYR B 2 130 ? 285.784 265.568 295.075 1.00 73.50  ? 128 TYR B CZ  1 
ATOM   4284  O  OH  . TYR B 2 130 ? 287.086 265.950 295.302 1.00 71.51  ? 128 TYR B OH  1 
ATOM   4285  N  N   . LYS B 2 131 ? 278.926 262.485 295.502 1.00 67.07  ? 129 LYS B N   1 
ATOM   4286  C  CA  . LYS B 2 131 ? 277.471 262.458 295.446 1.00 61.80  ? 129 LYS B CA  1 
ATOM   4287  C  C   . LYS B 2 131 ? 276.887 263.340 296.541 1.00 67.78  ? 129 LYS B C   1 
ATOM   4288  O  O   . LYS B 2 131 ? 277.309 263.277 297.699 1.00 74.87  ? 129 LYS B O   1 
ATOM   4289  C  CB  . LYS B 2 131 ? 276.961 261.026 295.591 1.00 64.14  ? 129 LYS B CB  1 
ATOM   4290  C  CG  . LYS B 2 131 ? 275.529 260.832 295.121 1.00 70.40  ? 129 LYS B CG  1 
ATOM   4291  C  CD  . LYS B 2 131 ? 275.202 259.363 294.913 1.00 72.48  ? 129 LYS B CD  1 
ATOM   4292  C  CE  . LYS B 2 131 ? 276.302 258.649 294.149 1.00 72.91  ? 129 LYS B CE  1 
ATOM   4293  N  NZ  . LYS B 2 131 ? 275.879 257.287 293.723 1.00 75.79  ? 129 LYS B NZ  1 
ATOM   4294  N  N   . ILE B 2 132 ? 275.910 264.161 296.173 1.00 64.33  ? 130 ILE B N   1 
ATOM   4295  C  CA  . ILE B 2 132 ? 275.312 265.104 297.111 1.00 68.15  ? 130 ILE B CA  1 
ATOM   4296  C  C   . ILE B 2 132 ? 274.273 264.390 297.962 1.00 74.02  ? 130 ILE B C   1 
ATOM   4297  O  O   . ILE B 2 132 ? 273.505 263.554 297.470 1.00 72.04  ? 130 ILE B O   1 
ATOM   4298  C  CB  . ILE B 2 132 ? 274.693 266.298 296.363 1.00 61.30  ? 130 ILE B CB  1 
ATOM   4299  C  CG1 . ILE B 2 132 ? 275.671 267.474 296.334 1.00 60.53  ? 130 ILE B CG1 1 
ATOM   4300  C  CG2 . ILE B 2 132 ? 273.373 266.704 297.001 1.00 59.75  ? 130 ILE B CG2 1 
ATOM   4301  C  CD1 . ILE B 2 132 ? 275.075 268.749 295.788 1.00 59.51  ? 130 ILE B CD1 1 
ATOM   4302  N  N   . LYS B 2 133 ? 274.249 264.721 299.249 1.00 76.05  ? 131 LYS B N   1 
ATOM   4303  C  CA  . LYS B 2 133 ? 273.244 264.219 300.175 1.00 77.92  ? 131 LYS B CA  1 
ATOM   4304  C  C   . LYS B 2 133 ? 272.167 265.283 300.332 1.00 80.19  ? 131 LYS B C   1 
ATOM   4305  O  O   . LYS B 2 133 ? 272.456 266.404 300.765 1.00 83.92  ? 131 LYS B O   1 
ATOM   4306  C  CB  . LYS B 2 133 ? 273.867 263.871 301.526 1.00 77.56  ? 131 LYS B CB  1 
ATOM   4307  C  CG  . LYS B 2 133 ? 274.676 262.586 301.522 1.00 80.02  ? 131 LYS B CG  1 
ATOM   4308  C  CD  . LYS B 2 133 ? 276.046 262.796 302.142 1.00 83.37  ? 131 LYS B CD  1 
ATOM   4309  C  CE  . LYS B 2 133 ? 277.058 261.798 301.603 1.00 80.33  ? 131 LYS B CE  1 
ATOM   4310  N  NZ  . LYS B 2 133 ? 276.572 260.396 301.713 1.00 81.92  ? 131 LYS B NZ  1 
ATOM   4311  N  N   . PHE B 2 134 ? 270.929 264.932 299.979 1.00 76.91  ? 132 PHE B N   1 
ATOM   4312  C  CA  . PHE B 2 134 ? 269.856 265.921 299.985 1.00 75.76  ? 132 PHE B CA  1 
ATOM   4313  C  C   . PHE B 2 134 ? 269.696 266.559 301.357 1.00 80.87  ? 132 PHE B C   1 
ATOM   4314  O  O   . PHE B 2 134 ? 269.364 267.745 301.462 1.00 80.89  ? 132 PHE B O   1 
ATOM   4315  C  CB  . PHE B 2 134 ? 268.545 265.281 299.535 1.00 74.49  ? 132 PHE B CB  1 
ATOM   4316  C  CG  . PHE B 2 134 ? 267.500 266.276 299.127 1.00 76.59  ? 132 PHE B CG  1 
ATOM   4317  C  CD1 . PHE B 2 134 ? 267.836 267.369 298.348 1.00 73.87  ? 132 PHE B CD1 1 
ATOM   4318  C  CD2 . PHE B 2 134 ? 266.183 266.119 299.519 1.00 78.70  ? 132 PHE B CD2 1 
ATOM   4319  C  CE1 . PHE B 2 134 ? 266.879 268.287 297.970 1.00 69.70  ? 132 PHE B CE1 1 
ATOM   4320  C  CE2 . PHE B 2 134 ? 265.222 267.034 299.143 1.00 72.64  ? 132 PHE B CE2 1 
ATOM   4321  C  CZ  . PHE B 2 134 ? 265.570 268.118 298.368 1.00 66.12  ? 132 PHE B CZ  1 
ATOM   4322  N  N   . GLN B 2 135 ? 269.926 265.790 302.423 1.00 82.76  ? 133 GLN B N   1 
ATOM   4323  C  CA  . GLN B 2 135 ? 269.810 266.348 303.765 1.00 81.24  ? 133 GLN B CA  1 
ATOM   4324  C  C   . GLN B 2 135 ? 270.799 267.488 303.973 1.00 82.52  ? 133 GLN B C   1 
ATOM   4325  O  O   . GLN B 2 135 ? 270.433 268.557 304.471 1.00 82.55  ? 133 GLN B O   1 
ATOM   4326  C  CB  . GLN B 2 135 ? 270.021 265.256 304.813 1.00 84.84  ? 133 GLN B CB  1 
ATOM   4327  C  CG  . GLN B 2 135 ? 270.431 265.794 306.174 1.00 84.85  ? 133 GLN B CG  1 
ATOM   4328  C  CD  . GLN B 2 135 ? 269.244 266.199 307.025 1.00 84.50  ? 133 GLN B CD  1 
ATOM   4329  O  OE1 . GLN B 2 135 ? 268.138 265.690 306.850 1.00 81.76  ? 133 GLN B OE1 1 
ATOM   4330  N  NE2 . GLN B 2 135 ? 269.468 267.126 307.949 1.00 81.31  ? 133 GLN B NE2 1 
ATOM   4331  N  N   . GLU B 2 136 ? 272.059 267.279 303.599 1.00 83.50  ? 134 GLU B N   1 
ATOM   4332  C  CA  . GLU B 2 136 ? 273.069 268.329 303.733 1.00 86.37  ? 134 GLU B CA  1 
ATOM   4333  C  C   . GLU B 2 136 ? 273.142 269.169 302.461 1.00 84.13  ? 134 GLU B C   1 
ATOM   4334  O  O   . GLU B 2 136 ? 274.206 269.445 301.915 1.00 87.37  ? 134 GLU B O   1 
ATOM   4335  C  CB  . GLU B 2 136 ? 274.421 267.709 304.076 1.00 88.47  ? 134 GLU B CB  1 
ATOM   4336  C  CG  . GLU B 2 136 ? 275.383 268.614 304.853 1.00 94.27  ? 134 GLU B CG  1 
ATOM   4337  C  CD  . GLU B 2 136 ? 275.913 269.795 304.058 1.00 102.33 ? 134 GLU B CD  1 
ATOM   4338  O  OE1 . GLU B 2 136 ? 276.401 269.588 302.927 1.00 102.24 ? 134 GLU B OE1 1 
ATOM   4339  O  OE2 . GLU B 2 136 ? 275.845 270.935 304.565 1.00 100.28 ? 134 GLU B OE2 1 
ATOM   4340  N  N   . PHE B 2 137 ? 271.973 269.552 301.962 1.00 81.58  ? 135 PHE B N   1 
ATOM   4341  C  CA  . PHE B 2 137 ? 271.860 270.586 300.940 1.00 77.27  ? 135 PHE B CA  1 
ATOM   4342  C  C   . PHE B 2 137 ? 270.782 271.616 301.238 1.00 78.56  ? 135 PHE B C   1 
ATOM   4343  O  O   . PHE B 2 137 ? 270.909 272.759 300.788 1.00 78.18  ? 135 PHE B O   1 
ATOM   4344  C  CB  . PHE B 2 137 ? 271.587 269.956 299.566 1.00 71.43  ? 135 PHE B CB  1 
ATOM   4345  C  CG  . PHE B 2 137 ? 271.125 270.939 298.529 1.00 69.11  ? 135 PHE B CG  1 
ATOM   4346  C  CD1 . PHE B 2 137 ? 272.040 271.664 297.788 1.00 69.87  ? 135 PHE B CD1 1 
ATOM   4347  C  CD2 . PHE B 2 137 ? 269.775 271.138 298.297 1.00 69.07  ? 135 PHE B CD2 1 
ATOM   4348  C  CE1 . PHE B 2 137 ? 271.618 272.570 296.836 1.00 69.07  ? 135 PHE B CE1 1 
ATOM   4349  C  CE2 . PHE B 2 137 ? 269.348 272.041 297.349 1.00 66.81  ? 135 PHE B CE2 1 
ATOM   4350  C  CZ  . PHE B 2 137 ? 270.270 272.758 296.616 1.00 67.48  ? 135 PHE B CZ  1 
ATOM   4351  N  N   . LEU B 2 138 ? 269.732 271.262 301.982 1.00 77.52  ? 136 LEU B N   1 
ATOM   4352  C  CA  . LEU B 2 138 ? 268.690 272.225 302.314 1.00 77.25  ? 136 LEU B CA  1 
ATOM   4353  C  C   . LEU B 2 138 ? 269.168 273.212 303.373 1.00 81.55  ? 136 LEU B C   1 
ATOM   4354  O  O   . LEU B 2 138 ? 268.962 274.424 303.244 1.00 82.00  ? 136 LEU B O   1 
ATOM   4355  C  CB  . LEU B 2 138 ? 267.436 271.486 302.783 1.00 76.82  ? 136 LEU B CB  1 
ATOM   4356  C  CG  . LEU B 2 138 ? 266.841 270.508 301.766 1.00 73.26  ? 136 LEU B CG  1 
ATOM   4357  C  CD1 . LEU B 2 138 ? 266.111 269.370 302.462 1.00 75.44  ? 136 LEU B CD1 1 
ATOM   4358  C  CD2 . LEU B 2 138 ? 265.916 271.235 300.803 1.00 73.02  ? 136 LEU B CD2 1 
ATOM   4359  N  N   . ASP B 2 139 ? 269.818 272.713 304.428 1.00 81.26  ? 137 ASP B N   1 
ATOM   4360  C  CA  . ASP B 2 139 ? 270.298 273.608 305.477 1.00 83.30  ? 137 ASP B CA  1 
ATOM   4361  C  C   . ASP B 2 139 ? 271.442 274.479 304.976 1.00 81.61  ? 137 ASP B C   1 
ATOM   4362  O  O   . ASP B 2 139 ? 271.528 275.662 305.323 1.00 77.57  ? 137 ASP B O   1 
ATOM   4363  C  CB  . ASP B 2 139 ? 270.732 272.813 306.711 1.00 82.53  ? 137 ASP B CB  1 
ATOM   4364  C  CG  . ASP B 2 139 ? 271.450 271.526 306.360 1.00 89.70  ? 137 ASP B CG  1 
ATOM   4365  O  OD1 . ASP B 2 139 ? 270.849 270.672 305.681 1.00 88.94  ? 137 ASP B OD1 1 
ATOM   4366  O  OD2 . ASP B 2 139 ? 272.620 271.367 306.769 1.00 94.41  ? 137 ASP B OD2 1 
ATOM   4367  N  N   . ARG B 2 140 ? 272.331 273.911 304.158 1.00 81.25  ? 138 ARG B N   1 
ATOM   4368  C  CA  . ARG B 2 140 ? 273.437 274.684 303.611 1.00 79.12  ? 138 ARG B CA  1 
ATOM   4369  C  C   . ARG B 2 140 ? 272.959 275.863 302.777 1.00 79.15  ? 138 ARG B C   1 
ATOM   4370  O  O   . ARG B 2 140 ? 273.695 276.845 302.633 1.00 76.20  ? 138 ARG B O   1 
ATOM   4371  C  CB  . ARG B 2 140 ? 274.340 273.781 302.768 1.00 79.11  ? 138 ARG B CB  1 
ATOM   4372  C  CG  . ARG B 2 140 ? 275.200 274.530 301.766 1.00 80.37  ? 138 ARG B CG  1 
ATOM   4373  C  CD  . ARG B 2 140 ? 276.557 273.872 301.595 1.00 86.06  ? 138 ARG B CD  1 
ATOM   4374  N  NE  . ARG B 2 140 ? 277.256 274.375 300.418 1.00 90.55  ? 138 ARG B NE  1 
ATOM   4375  C  CZ  . ARG B 2 140 ? 278.370 273.851 299.927 1.00 90.86  ? 138 ARG B CZ  1 
ATOM   4376  N  NH1 . ARG B 2 140 ? 278.947 272.801 300.488 1.00 90.02  ? 138 ARG B NH1 1 
ATOM   4377  N  NH2 . ARG B 2 140 ? 278.921 274.395 298.845 1.00 85.43  ? 138 ARG B NH2 1 
ATOM   4378  N  N   . PHE B 2 141 ? 271.746 275.792 302.226 1.00 79.86  ? 139 PHE B N   1 
ATOM   4379  C  CA  . PHE B 2 141 ? 271.209 276.853 301.381 1.00 77.90  ? 139 PHE B CA  1 
ATOM   4380  C  C   . PHE B 2 141 ? 269.918 277.440 301.942 1.00 78.54  ? 139 PHE B C   1 
ATOM   4381  O  O   . PHE B 2 141 ? 269.159 278.076 301.206 1.00 80.51  ? 139 PHE B O   1 
ATOM   4382  C  CB  . PHE B 2 141 ? 270.990 276.338 299.957 1.00 76.45  ? 139 PHE B CB  1 
ATOM   4383  C  CG  . PHE B 2 141 ? 272.263 276.014 299.230 1.00 74.40  ? 139 PHE B CG  1 
ATOM   4384  C  CD1 . PHE B 2 141 ? 272.991 277.010 298.602 1.00 73.81  ? 139 PHE B CD1 1 
ATOM   4385  C  CD2 . PHE B 2 141 ? 272.736 274.715 299.181 1.00 73.16  ? 139 PHE B CD2 1 
ATOM   4386  C  CE1 . PHE B 2 141 ? 274.164 276.715 297.935 1.00 73.40  ? 139 PHE B CE1 1 
ATOM   4387  C  CE2 . PHE B 2 141 ? 273.909 274.414 298.516 1.00 73.89  ? 139 PHE B CE2 1 
ATOM   4388  C  CZ  . PHE B 2 141 ? 274.623 275.415 297.892 1.00 71.17  ? 139 PHE B CZ  1 
ATOM   4389  N  N   . GLY B 2 142 ? 269.655 277.240 303.231 1.00 79.65  ? 140 GLY B N   1 
ATOM   4390  C  CA  . GLY B 2 142 ? 268.519 277.863 303.881 1.00 79.91  ? 140 GLY B CA  1 
ATOM   4391  C  C   . GLY B 2 142 ? 267.169 277.478 303.313 1.00 80.61  ? 140 GLY B C   1 
ATOM   4392  O  O   . GLY B 2 142 ? 266.324 278.345 303.071 1.00 82.88  ? 140 GLY B O   1 
ATOM   4393  N  N   . ILE B 2 143 ? 266.950 276.186 303.093 1.00 77.25  ? 141 ILE B N   1 
ATOM   4394  C  CA  . ILE B 2 143 ? 265.678 275.672 302.601 1.00 77.44  ? 141 ILE B CA  1 
ATOM   4395  C  C   . ILE B 2 143 ? 265.011 274.932 303.753 1.00 79.66  ? 141 ILE B C   1 
ATOM   4396  O  O   . ILE B 2 143 ? 265.503 273.891 304.204 1.00 79.10  ? 141 ILE B O   1 
ATOM   4397  C  CB  . ILE B 2 143 ? 265.860 274.762 301.380 1.00 76.21  ? 141 ILE B CB  1 
ATOM   4398  C  CG1 . ILE B 2 143 ? 266.506 275.537 300.231 1.00 73.64  ? 141 ILE B CG1 1 
ATOM   4399  C  CG2 . ILE B 2 143 ? 264.524 274.193 300.937 1.00 76.05  ? 141 ILE B CG2 1 
ATOM   4400  C  CD1 . ILE B 2 143 ? 267.687 274.833 299.610 1.00 74.04  ? 141 ILE B CD1 1 
ATOM   4401  N  N   . TYR B 2 144 ? 263.892 275.469 304.229 1.00 84.87  ? 142 TYR B N   1 
ATOM   4402  C  CA  . TYR B 2 144 ? 263.190 274.873 305.356 1.00 85.85  ? 142 TYR B CA  1 
ATOM   4403  C  C   . TYR B 2 144 ? 262.462 273.608 304.919 1.00 86.45  ? 142 TYR B C   1 
ATOM   4404  O  O   . TYR B 2 144 ? 261.917 273.534 303.814 1.00 83.54  ? 142 TYR B O   1 
ATOM   4405  C  CB  . TYR B 2 144 ? 262.205 275.878 305.951 1.00 87.06  ? 142 TYR B CB  1 
ATOM   4406  C  CG  . TYR B 2 144 ? 261.345 275.329 307.067 1.00 89.40  ? 142 TYR B CG  1 
ATOM   4407  C  CD1 . TYR B 2 144 ? 261.810 275.297 308.375 1.00 87.09  ? 142 TYR B CD1 1 
ATOM   4408  C  CD2 . TYR B 2 144 ? 260.067 274.853 306.816 1.00 89.69  ? 142 TYR B CD2 1 
ATOM   4409  C  CE1 . TYR B 2 144 ? 261.028 274.802 309.399 1.00 87.73  ? 142 TYR B CE1 1 
ATOM   4410  C  CE2 . TYR B 2 144 ? 259.278 274.355 307.833 1.00 91.00  ? 142 TYR B CE2 1 
ATOM   4411  C  CZ  . TYR B 2 144 ? 259.763 274.332 309.123 1.00 91.89  ? 142 TYR B CZ  1 
ATOM   4412  O  OH  . TYR B 2 144 ? 258.982 273.836 310.141 1.00 95.60  ? 142 TYR B OH  1 
ATOM   4413  N  N   . TYR B 2 145 ? 262.451 272.607 305.798 1.00 85.55  ? 143 TYR B N   1 
ATOM   4414  C  CA  . TYR B 2 145 ? 261.819 271.334 305.488 1.00 85.06  ? 143 TYR B CA  1 
ATOM   4415  C  C   . TYR B 2 145 ? 261.271 270.714 306.765 1.00 89.08  ? 143 TYR B C   1 
ATOM   4416  O  O   . TYR B 2 145 ? 261.670 271.070 307.876 1.00 91.54  ? 143 TYR B O   1 
ATOM   4417  C  CB  . TYR B 2 145 ? 262.795 270.372 304.801 1.00 83.21  ? 143 TYR B CB  1 
ATOM   4418  C  CG  . TYR B 2 145 ? 263.931 269.912 305.684 1.00 81.05  ? 143 TYR B CG  1 
ATOM   4419  C  CD1 . TYR B 2 145 ? 265.057 270.702 305.867 1.00 78.77  ? 143 TYR B CD1 1 
ATOM   4420  C  CD2 . TYR B 2 145 ? 263.879 268.687 306.330 1.00 83.42  ? 143 TYR B CD2 1 
ATOM   4421  C  CE1 . TYR B 2 145 ? 266.096 270.285 306.671 1.00 77.24  ? 143 TYR B CE1 1 
ATOM   4422  C  CE2 . TYR B 2 145 ? 264.913 268.262 307.136 1.00 82.88  ? 143 TYR B CE2 1 
ATOM   4423  C  CZ  . TYR B 2 145 ? 266.019 269.064 307.302 1.00 79.75  ? 143 TYR B CZ  1 
ATOM   4424  O  OH  . TYR B 2 145 ? 267.051 268.640 308.106 1.00 82.22  ? 143 TYR B OH  1 
ATOM   4425  N  N   . GLN B 2 146 ? 260.348 269.781 306.586 1.00 90.78  ? 144 GLN B N   1 
ATOM   4426  C  CA  . GLN B 2 146 ? 259.706 269.044 307.661 1.00 93.19  ? 144 GLN B CA  1 
ATOM   4427  C  C   . GLN B 2 146 ? 259.814 267.557 307.377 1.00 94.61  ? 144 GLN B C   1 
ATOM   4428  O  O   . GLN B 2 146 ? 260.012 267.149 306.227 1.00 91.25  ? 144 GLN B O   1 
ATOM   4429  C  CB  . GLN B 2 146 ? 258.227 269.435 307.803 1.00 94.13  ? 144 GLN B CB  1 
ATOM   4430  C  CG  . GLN B 2 146 ? 257.966 270.930 307.769 1.00 94.16  ? 144 GLN B CG  1 
ATOM   4431  C  CD  . GLN B 2 146 ? 257.371 271.444 309.064 1.00 97.01  ? 144 GLN B CD  1 
ATOM   4432  O  OE1 . GLN B 2 146 ? 257.612 270.886 310.135 1.00 99.42  ? 144 GLN B OE1 1 
ATOM   4433  N  NE2 . GLN B 2 146 ? 256.587 272.511 308.973 1.00 91.06  ? 144 GLN B NE2 1 
ATOM   4434  N  N   . PRO B 2 147 ? 259.695 266.718 308.403 1.00 98.74  ? 145 PRO B N   1 
ATOM   4435  C  CA  . PRO B 2 147 ? 259.709 265.271 308.165 1.00 97.44  ? 145 PRO B CA  1 
ATOM   4436  C  C   . PRO B 2 147 ? 258.613 264.875 307.189 1.00 96.36  ? 145 PRO B C   1 
ATOM   4437  O  O   . PRO B 2 147 ? 257.504 265.411 307.218 1.00 94.70  ? 145 PRO B O   1 
ATOM   4438  C  CB  . PRO B 2 147 ? 259.469 264.680 309.558 1.00 97.05  ? 145 PRO B CB  1 
ATOM   4439  C  CG  . PRO B 2 147 ? 259.957 265.729 310.495 1.00 96.11  ? 145 PRO B CG  1 
ATOM   4440  C  CD  . PRO B 2 147 ? 259.638 267.043 309.838 1.00 96.18  ? 145 PRO B CD  1 
ATOM   4441  N  N   . SER B 2 148 ? 258.938 263.929 306.314 1.00 97.97  ? 146 SER B N   1 
ATOM   4442  C  CA  . SER B 2 148 ? 258.003 263.497 305.288 1.00 96.91  ? 146 SER B CA  1 
ATOM   4443  C  C   . SER B 2 148 ? 256.951 262.569 305.879 1.00 101.18 ? 146 SER B C   1 
ATOM   4444  O  O   . SER B 2 148 ? 257.253 261.718 306.721 1.00 100.73 ? 146 SER B O   1 
ATOM   4445  C  CB  . SER B 2 148 ? 258.745 262.788 304.156 1.00 92.45  ? 146 SER B CB  1 
ATOM   4446  O  OG  . SER B 2 148 ? 259.591 261.773 304.664 1.00 93.93  ? 146 SER B OG  1 
ATOM   4447  N  N   . THR B 2 149 ? 255.707 262.741 305.431 1.00 104.48 ? 147 THR B N   1 
ATOM   4448  C  CA  . THR B 2 149 ? 254.652 261.814 305.817 1.00 109.02 ? 147 THR B CA  1 
ATOM   4449  C  C   . THR B 2 149 ? 254.818 260.460 305.145 1.00 109.29 ? 147 THR B C   1 
ATOM   4450  O  O   . THR B 2 149 ? 254.221 259.477 305.597 1.00 107.49 ? 147 THR B O   1 
ATOM   4451  C  CB  . THR B 2 149 ? 253.280 262.399 305.479 1.00 111.41 ? 147 THR B CB  1 
ATOM   4452  O  OG1 . THR B 2 149 ? 253.050 262.296 304.068 1.00 110.70 ? 147 THR B OG1 1 
ATOM   4453  C  CG2 . THR B 2 149 ? 253.212 263.862 305.893 1.00 102.94 ? 147 THR B CG2 1 
ATOM   4454  N  N   . ASN B 2 150 ? 255.613 260.390 304.080 1.00 109.25 ? 148 ASN B N   1 
ATOM   4455  C  CA  . ASN B 2 150 ? 255.923 259.139 303.409 1.00 108.67 ? 148 ASN B CA  1 
ATOM   4456  C  C   . ASN B 2 150 ? 257.413 259.097 303.110 1.00 105.14 ? 148 ASN B C   1 
ATOM   4457  O  O   . ASN B 2 150 ? 258.052 260.134 302.916 1.00 104.30 ? 148 ASN B O   1 
ATOM   4458  C  CB  . ASN B 2 150 ? 255.118 258.977 302.112 1.00 104.57 ? 148 ASN B CB  1 
ATOM   4459  C  CG  . ASN B 2 150 ? 255.158 257.561 301.575 1.00 108.03 ? 148 ASN B CG  1 
ATOM   4460  O  OD1 . ASN B 2 150 ? 255.679 256.654 302.223 1.00 107.93 ? 148 ASN B OD1 1 
ATOM   4461  N  ND2 . ASN B 2 150 ? 254.606 257.363 300.383 1.00 106.37 ? 148 ASN B ND2 1 
ATOM   4462  N  N   . LYS B 2 151 ? 257.962 257.886 303.079 1.00 105.45 ? 149 LYS B N   1 
ATOM   4463  C  CA  . LYS B 2 151 ? 259.357 257.671 302.722 1.00 104.24 ? 149 LYS B CA  1 
ATOM   4464  C  C   . LYS B 2 151 ? 259.524 257.194 301.288 1.00 105.37 ? 149 LYS B C   1 
ATOM   4465  O  O   . LYS B 2 151 ? 260.651 256.919 300.866 1.00 101.57 ? 149 LYS B O   1 
ATOM   4466  C  CB  . LYS B 2 151 ? 260.017 256.666 303.679 1.00 104.42 ? 149 LYS B CB  1 
ATOM   4467  C  CG  . LYS B 2 151 ? 260.101 257.084 305.153 1.00 103.30 ? 149 LYS B CG  1 
ATOM   4468  C  CD  . LYS B 2 151 ? 258.776 257.556 305.733 1.00 104.10 ? 149 LYS B CD  1 
ATOM   4469  C  CE  . LYS B 2 151 ? 257.748 256.438 305.743 1.00 103.61 ? 149 LYS B CE  1 
ATOM   4470  N  NZ  . LYS B 2 151 ? 256.415 256.917 306.200 1.00 103.03 ? 149 LYS B NZ  1 
ATOM   4471  N  N   . ASN B 2 152 ? 258.434 257.092 300.531 1.00 107.17 ? 150 ASN B N   1 
ATOM   4472  C  CA  . ASN B 2 152 ? 258.472 256.651 299.143 1.00 105.20 ? 150 ASN B CA  1 
ATOM   4473  C  C   . ASN B 2 152 ? 258.344 257.878 298.248 1.00 101.96 ? 150 ASN B C   1 
ATOM   4474  O  O   . ASN B 2 152 ? 257.310 258.554 298.252 1.00 101.41 ? 150 ASN B O   1 
ATOM   4475  C  CB  . ASN B 2 152 ? 257.361 255.642 298.863 1.00 106.24 ? 150 ASN B CB  1 
ATOM   4476  C  CG  . ASN B 2 152 ? 257.236 254.594 299.952 1.00 110.43 ? 150 ASN B CG  1 
ATOM   4477  O  OD1 . ASN B 2 152 ? 258.229 254.185 300.554 1.00 112.99 ? 150 ASN B OD1 1 
ATOM   4478  N  ND2 . ASN B 2 152 ? 256.010 254.155 300.213 1.00 106.77 ? 150 ASN B ND2 1 
ATOM   4479  N  N   . ALA B 2 153 ? 259.396 258.161 297.481 1.00 98.02  ? 151 ALA B N   1 
ATOM   4480  C  CA  . ALA B 2 153 ? 259.442 259.335 296.611 1.00 95.06  ? 151 ALA B CA  1 
ATOM   4481  C  C   . ALA B 2 153 ? 259.319 260.630 297.407 1.00 91.52  ? 151 ALA B C   1 
ATOM   4482  O  O   . ALA B 2 153 ? 258.877 261.655 296.882 1.00 88.34  ? 151 ALA B O   1 
ATOM   4483  C  CB  . ALA B 2 153 ? 258.358 259.269 295.532 1.00 91.09  ? 151 ALA B CB  1 
ATOM   4484  N  N   . GLU B 2 154 ? 259.709 260.593 298.684 1.00 89.37  ? 152 GLU B N   1 
ATOM   4485  C  CA  . GLU B 2 154 ? 259.700 261.796 299.516 1.00 85.87  ? 152 GLU B CA  1 
ATOM   4486  C  C   . GLU B 2 154 ? 260.722 261.599 300.635 1.00 84.91  ? 152 GLU B C   1 
ATOM   4487  O  O   . GLU B 2 154 ? 260.439 260.908 301.617 1.00 88.32  ? 152 GLU B O   1 
ATOM   4488  C  CB  . GLU B 2 154 ? 258.313 262.070 300.072 1.00 87.33  ? 152 GLU B CB  1 
ATOM   4489  C  CG  . GLU B 2 154 ? 258.080 263.521 300.452 1.00 87.15  ? 152 GLU B CG  1 
ATOM   4490  C  CD  . GLU B 2 154 ? 257.274 264.274 299.416 1.00 92.18  ? 152 GLU B CD  1 
ATOM   4491  O  OE1 . GLU B 2 154 ? 256.788 263.634 298.461 1.00 97.65  ? 152 GLU B OE1 1 
ATOM   4492  O  OE2 . GLU B 2 154 ? 257.126 265.505 299.555 1.00 91.48  ? 152 GLU B OE2 1 
ATOM   4493  N  N   . LEU B 2 155 ? 261.898 262.207 300.476 1.00 79.77  ? 153 LEU B N   1 
ATOM   4494  C  CA  . LEU B 2 155 ? 262.887 262.185 301.547 1.00 80.44  ? 153 LEU B CA  1 
ATOM   4495  C  C   . LEU B 2 155 ? 262.523 263.164 302.656 1.00 83.16  ? 153 LEU B C   1 
ATOM   4496  O  O   . LEU B 2 155 ? 262.736 262.874 303.839 1.00 83.01  ? 153 LEU B O   1 
ATOM   4497  C  CB  . LEU B 2 155 ? 264.275 262.502 300.991 1.00 82.05  ? 153 LEU B CB  1 
ATOM   4498  C  CG  . LEU B 2 155 ? 264.830 261.536 299.943 1.00 81.57  ? 153 LEU B CG  1 
ATOM   4499  C  CD1 . LEU B 2 155 ? 266.224 261.963 299.514 1.00 77.44  ? 153 LEU B CD1 1 
ATOM   4500  C  CD2 . LEU B 2 155 ? 264.839 260.112 300.473 1.00 76.55  ? 153 LEU B CD2 1 
ATOM   4501  N  N   . PHE B 2 156 ? 261.980 264.324 302.293 1.00 82.23  ? 154 PHE B N   1 
ATOM   4502  C  CA  . PHE B 2 156 ? 261.555 265.330 303.253 1.00 83.77  ? 154 PHE B CA  1 
ATOM   4503  C  C   . PHE B 2 156 ? 260.306 266.013 302.713 1.00 85.91  ? 154 PHE B C   1 
ATOM   4504  O  O   . PHE B 2 156 ? 259.760 265.627 301.676 1.00 84.51  ? 154 PHE B O   1 
ATOM   4505  C  CB  . PHE B 2 156 ? 262.671 266.345 303.533 1.00 80.37  ? 154 PHE B CB  1 
ATOM   4506  C  CG  . PHE B 2 156 ? 263.970 265.718 303.957 1.00 83.01  ? 154 PHE B CG  1 
ATOM   4507  C  CD1 . PHE B 2 156 ? 264.899 265.306 303.015 1.00 84.15  ? 154 PHE B CD1 1 
ATOM   4508  C  CD2 . PHE B 2 156 ? 264.256 265.529 305.299 1.00 79.81  ? 154 PHE B CD2 1 
ATOM   4509  C  CE1 . PHE B 2 156 ? 266.091 264.726 303.405 1.00 82.78  ? 154 PHE B CE1 1 
ATOM   4510  C  CE2 . PHE B 2 156 ? 265.446 264.949 305.694 1.00 78.33  ? 154 PHE B CE2 1 
ATOM   4511  C  CZ  . PHE B 2 156 ? 266.364 264.547 304.745 1.00 81.60  ? 154 PHE B CZ  1 
ATOM   4512  N  N   . LYS B 2 157 ? 259.846 267.037 303.429 1.00 89.63  ? 155 LYS B N   1 
ATOM   4513  C  CA  . LYS B 2 157 ? 258.677 267.817 303.036 1.00 88.42  ? 155 LYS B CA  1 
ATOM   4514  C  C   . LYS B 2 157 ? 259.108 269.267 302.866 1.00 86.00  ? 155 LYS B C   1 
ATOM   4515  O  O   . LYS B 2 157 ? 259.410 269.949 303.850 1.00 84.19  ? 155 LYS B O   1 
ATOM   4516  C  CB  . LYS B 2 157 ? 257.558 267.696 304.069 1.00 92.57  ? 155 LYS B CB  1 
ATOM   4517  C  CG  . LYS B 2 157 ? 256.363 268.593 303.787 1.00 93.95  ? 155 LYS B CG  1 
ATOM   4518  C  CD  . LYS B 2 157 ? 255.281 268.422 304.839 1.00 97.15  ? 155 LYS B CD  1 
ATOM   4519  C  CE  . LYS B 2 157 ? 254.247 267.396 304.407 1.00 97.08  ? 155 LYS B CE  1 
ATOM   4520  N  NZ  . LYS B 2 157 ? 253.719 267.682 303.044 1.00 95.13  ? 155 LYS B NZ  1 
ATOM   4521  N  N   . VAL B 2 158 ? 259.135 269.735 301.621 1.00 84.95  ? 156 VAL B N   1 
ATOM   4522  C  CA  . VAL B 2 158 ? 259.530 271.098 301.292 1.00 80.06  ? 156 VAL B CA  1 
ATOM   4523  C  C   . VAL B 2 158 ? 258.371 271.772 300.575 1.00 77.51  ? 156 VAL B C   1 
ATOM   4524  O  O   . VAL B 2 158 ? 257.837 271.230 299.600 1.00 78.47  ? 156 VAL B O   1 
ATOM   4525  C  CB  . VAL B 2 158 ? 260.802 271.128 300.427 1.00 73.24  ? 156 VAL B CB  1 
ATOM   4526  C  CG1 . VAL B 2 158 ? 261.457 272.498 300.491 1.00 72.74  ? 156 VAL B CG1 1 
ATOM   4527  C  CG2 . VAL B 2 158 ? 261.772 270.045 300.874 1.00 71.38  ? 156 VAL B CG2 1 
ATOM   4528  N  N   . ALA B 2 159 ? 257.981 272.948 301.059 1.00 77.80  ? 157 ALA B N   1 
ATOM   4529  C  CA  . ALA B 2 159 ? 256.903 273.696 300.434 1.00 76.95  ? 157 ALA B CA  1 
ATOM   4530  C  C   . ALA B 2 159 ? 257.378 274.331 299.130 1.00 77.11  ? 157 ALA B C   1 
ATOM   4531  O  O   . ALA B 2 159 ? 258.572 274.552 298.911 1.00 78.99  ? 157 ALA B O   1 
ATOM   4532  C  CB  . ALA B 2 159 ? 256.375 274.770 301.385 1.00 74.68  ? 157 ALA B CB  1 
ATOM   4533  N  N   . ASP B 2 160 ? 256.417 274.626 298.253 1.00 73.97  ? 158 ASP B N   1 
ATOM   4534  C  CA  . ASP B 2 160 ? 256.757 275.232 296.970 1.00 74.35  ? 158 ASP B CA  1 
ATOM   4535  C  C   . ASP B 2 160 ? 257.423 276.588 297.161 1.00 73.97  ? 158 ASP B C   1 
ATOM   4536  O  O   . ASP B 2 160 ? 258.388 276.919 296.462 1.00 74.13  ? 158 ASP B O   1 
ATOM   4537  C  CB  . ASP B 2 160 ? 255.508 275.365 296.101 1.00 76.31  ? 158 ASP B CB  1 
ATOM   4538  C  CG  . ASP B 2 160 ? 255.163 274.080 295.378 1.00 79.25  ? 158 ASP B CG  1 
ATOM   4539  O  OD1 . ASP B 2 160 ? 255.984 273.139 295.411 1.00 79.67  ? 158 ASP B OD1 1 
ATOM   4540  O  OD2 . ASP B 2 160 ? 254.072 274.011 294.775 1.00 76.46  ? 158 ASP B OD2 1 
ATOM   4541  N  N   . SER B 2 161 ? 256.920 277.391 298.101 1.00 75.24  ? 159 SER B N   1 
ATOM   4542  C  CA  . SER B 2 161 ? 257.528 278.691 298.361 1.00 74.65  ? 159 SER B CA  1 
ATOM   4543  C  C   . SER B 2 161 ? 258.961 278.549 298.858 1.00 77.10  ? 159 SER B C   1 
ATOM   4544  O  O   . SER B 2 161 ? 259.799 279.417 298.588 1.00 75.54  ? 159 SER B O   1 
ATOM   4545  C  CB  . SER B 2 161 ? 256.686 279.470 299.370 1.00 77.18  ? 159 SER B CB  1 
ATOM   4546  O  OG  . SER B 2 161 ? 256.314 278.650 300.464 1.00 77.90  ? 159 SER B OG  1 
ATOM   4547  N  N   . ASP B 2 162 ? 259.261 277.469 299.581 1.00 75.09  ? 160 ASP B N   1 
ATOM   4548  C  CA  . ASP B 2 162 ? 260.615 277.254 300.078 1.00 72.48  ? 160 ASP B CA  1 
ATOM   4549  C  C   . ASP B 2 162 ? 261.563 276.789 298.981 1.00 69.55  ? 160 ASP B C   1 
ATOM   4550  O  O   . ASP B 2 162 ? 262.753 277.122 299.017 1.00 66.19  ? 160 ASP B O   1 
ATOM   4551  C  CB  . ASP B 2 162 ? 260.601 276.238 301.221 1.00 77.96  ? 160 ASP B CB  1 
ATOM   4552  C  CG  . ASP B 2 162 ? 259.451 276.459 302.182 1.00 84.47  ? 160 ASP B CG  1 
ATOM   4553  O  OD1 . ASP B 2 162 ? 259.062 277.629 302.385 1.00 83.58  ? 160 ASP B OD1 1 
ATOM   4554  O  OD2 . ASP B 2 162 ? 258.935 275.464 302.732 1.00 83.89  ? 160 ASP B OD2 1 
ATOM   4555  N  N   . ILE B 2 163 ? 261.068 276.026 298.012 1.00 69.30  ? 161 ILE B N   1 
ATOM   4556  C  CA  . ILE B 2 163 ? 261.893 275.548 296.904 1.00 65.59  ? 161 ILE B CA  1 
ATOM   4557  C  C   . ILE B 2 163 ? 262.264 276.738 296.027 1.00 61.85  ? 161 ILE B C   1 
ATOM   4558  O  O   . ILE B 2 163 ? 261.375 277.442 295.529 1.00 59.29  ? 161 ILE B O   1 
ATOM   4559  C  CB  . ILE B 2 163 ? 261.170 274.461 296.095 1.00 60.61  ? 161 ILE B CB  1 
ATOM   4560  C  CG1 . ILE B 2 163 ? 260.680 273.346 297.019 1.00 62.22  ? 161 ILE B CG1 1 
ATOM   4561  C  CG2 . ILE B 2 163 ? 262.086 273.898 295.020 1.00 53.93  ? 161 ILE B CG2 1 
ATOM   4562  C  CD1 . ILE B 2 163 ? 259.754 272.358 296.345 1.00 61.52  ? 161 ILE B CD1 1 
ATOM   4563  N  N   . PRO B 2 164 ? 263.552 276.995 295.806 1.00 60.41  ? 162 PRO B N   1 
ATOM   4564  C  CA  . PRO B 2 164 ? 263.981 278.190 295.046 1.00 53.66  ? 162 PRO B CA  1 
ATOM   4565  C  C   . PRO B 2 164 ? 263.904 277.984 293.537 1.00 52.27  ? 162 PRO B C   1 
ATOM   4566  O  O   . PRO B 2 164 ? 264.907 277.931 292.820 1.00 54.82  ? 162 PRO B O   1 
ATOM   4567  C  CB  . PRO B 2 164 ? 265.419 278.400 295.540 1.00 54.34  ? 162 PRO B CB  1 
ATOM   4568  C  CG  . PRO B 2 164 ? 265.740 277.243 296.474 1.00 56.64  ? 162 PRO B CG  1 
ATOM   4569  C  CD  . PRO B 2 164 ? 264.695 276.206 296.281 1.00 57.28  ? 162 PRO B CD  1 
ATOM   4570  N  N   . SER B 2 165 ? 262.679 277.870 293.026 1.00 52.58  ? 163 SER B N   1 
ATOM   4571  C  CA  . SER B 2 165 ? 262.487 277.718 291.590 1.00 48.97  ? 163 SER B CA  1 
ATOM   4572  C  C   . SER B 2 165 ? 262.501 279.049 290.853 1.00 52.81  ? 163 SER B C   1 
ATOM   4573  O  O   . SER B 2 165 ? 262.776 279.072 289.649 1.00 56.72  ? 163 SER B O   1 
ATOM   4574  C  CB  . SER B 2 165 ? 261.176 276.985 291.307 1.00 49.27  ? 163 SER B CB  1 
ATOM   4575  O  OG  . SER B 2 165 ? 261.267 275.629 291.700 1.00 57.28  ? 163 SER B OG  1 
ATOM   4576  N  N   . ALA B 2 166 ? 262.209 280.152 291.542 1.00 51.33  ? 164 ALA B N   1 
ATOM   4577  C  CA  . ALA B 2 166 ? 262.286 281.475 290.941 1.00 51.18  ? 164 ALA B CA  1 
ATOM   4578  C  C   . ALA B 2 166 ? 263.611 282.172 291.202 1.00 54.19  ? 164 ALA B C   1 
ATOM   4579  O  O   . ALA B 2 166 ? 263.973 283.082 290.449 1.00 55.55  ? 164 ALA B O   1 
ATOM   4580  C  CB  . ALA B 2 166 ? 261.145 282.361 291.452 1.00 51.43  ? 164 ALA B CB  1 
ATOM   4581  N  N   . GLU B 2 167 ? 264.336 281.771 292.248 1.00 55.24  ? 165 GLU B N   1 
ATOM   4582  C  CA  . GLU B 2 167 ? 265.641 282.355 292.530 1.00 52.62  ? 165 GLU B CA  1 
ATOM   4583  C  C   . GLU B 2 167 ? 266.714 281.847 291.577 1.00 49.70  ? 165 GLU B C   1 
ATOM   4584  O  O   . GLU B 2 167 ? 267.688 282.560 291.312 1.00 54.10  ? 165 GLU B O   1 
ATOM   4585  C  CB  . GLU B 2 167 ? 266.043 282.067 293.976 1.00 54.94  ? 165 GLU B CB  1 
ATOM   4586  C  CG  . GLU B 2 167 ? 265.455 283.039 294.982 1.00 63.37  ? 165 GLU B CG  1 
ATOM   4587  C  CD  . GLU B 2 167 ? 263.946 282.946 295.071 1.00 68.11  ? 165 GLU B CD  1 
ATOM   4588  O  OE1 . GLU B 2 167 ? 263.436 281.876 295.461 1.00 67.33  ? 165 GLU B OE1 1 
ATOM   4589  O  OE2 . GLU B 2 167 ? 263.269 283.945 294.748 1.00 72.50  ? 165 GLU B OE2 1 
ATOM   4590  N  N   . VAL B 2 168 ? 266.561 280.630 291.061 1.00 45.74  ? 166 VAL B N   1 
ATOM   4591  C  CA  . VAL B 2 168 ? 267.515 280.059 290.112 1.00 44.14  ? 166 VAL B CA  1 
ATOM   4592  C  C   . VAL B 2 168 ? 267.259 280.723 288.763 1.00 45.64  ? 166 VAL B C   1 
ATOM   4593  O  O   . VAL B 2 168 ? 266.340 280.345 288.036 1.00 46.06  ? 166 VAL B O   1 
ATOM   4594  C  CB  . VAL B 2 168 ? 267.393 278.536 290.028 1.00 40.32  ? 166 VAL B CB  1 
ATOM   4595  C  CG1 . VAL B 2 168 ? 268.198 278.003 288.853 1.00 37.53  ? 166 VAL B CG1 1 
ATOM   4596  C  CG2 . VAL B 2 168 ? 267.843 277.898 291.331 1.00 36.58  ? 166 VAL B CG2 1 
ATOM   4597  N  N   . LYS B 2 169 ? 268.079 281.719 288.420 1.00 44.17  ? 167 LYS B N   1 
ATOM   4598  C  CA  . LYS B 2 169 ? 267.907 282.484 287.191 1.00 41.75  ? 167 LYS B CA  1 
ATOM   4599  C  C   . LYS B 2 169 ? 269.078 282.312 286.231 1.00 44.10  ? 167 LYS B C   1 
ATOM   4600  O  O   . LYS B 2 169 ? 269.233 283.110 285.302 1.00 45.23  ? 167 LYS B O   1 
ATOM   4601  C  CB  . LYS B 2 169 ? 267.703 283.965 287.510 1.00 50.32  ? 167 LYS B CB  1 
ATOM   4602  C  CG  . LYS B 2 169 ? 266.287 284.323 287.916 1.00 51.76  ? 167 LYS B CG  1 
ATOM   4603  C  CD  . LYS B 2 169 ? 266.282 285.153 289.185 1.00 54.77  ? 167 LYS B CD  1 
ATOM   4604  C  CE  . LYS B 2 169 ? 265.085 286.083 289.232 1.00 57.13  ? 167 LYS B CE  1 
ATOM   4605  N  NZ  . LYS B 2 169 ? 265.253 287.149 290.256 1.00 60.07  ? 167 LYS B NZ  1 
ATOM   4606  N  N   . ALA B 2 170 ? 269.907 281.291 286.432 1.00 43.91  ? 168 ALA B N   1 
ATOM   4607  C  CA  . ALA B 2 170 ? 271.042 281.061 285.552 1.00 37.83  ? 168 ALA B CA  1 
ATOM   4608  C  C   . ALA B 2 170 ? 271.460 279.603 285.645 1.00 34.60  ? 168 ALA B C   1 
ATOM   4609  O  O   . ALA B 2 170 ? 271.256 278.949 286.670 1.00 37.65  ? 168 ALA B O   1 
ATOM   4610  C  CB  . ALA B 2 170 ? 272.219 281.979 285.901 1.00 34.44  ? 168 ALA B CB  1 
ATOM   4611  N  N   . TYR B 2 171 ? 272.050 279.106 284.560 1.00 34.53  ? 169 TYR B N   1 
ATOM   4612  C  CA  . TYR B 2 171 ? 272.533 277.735 284.488 1.00 31.39  ? 169 TYR B CA  1 
ATOM   4613  C  C   . TYR B 2 171 ? 273.953 277.694 283.942 1.00 32.53  ? 169 TYR B C   1 
ATOM   4614  O  O   . TYR B 2 171 ? 274.343 278.519 283.113 1.00 35.46  ? 169 TYR B O   1 
ATOM   4615  C  CB  . TYR B 2 171 ? 271.634 276.856 283.607 1.00 34.01  ? 169 TYR B CB  1 
ATOM   4616  C  CG  . TYR B 2 171 ? 270.412 276.317 284.310 1.00 36.24  ? 169 TYR B CG  1 
ATOM   4617  C  CD1 . TYR B 2 171 ? 270.453 275.096 284.969 1.00 32.24  ? 169 TYR B CD1 1 
ATOM   4618  C  CD2 . TYR B 2 171 ? 269.219 277.022 284.311 1.00 36.91  ? 169 TYR B CD2 1 
ATOM   4619  C  CE1 . TYR B 2 171 ? 269.342 274.597 285.610 1.00 38.45  ? 169 TYR B CE1 1 
ATOM   4620  C  CE2 . TYR B 2 171 ? 268.104 276.532 284.952 1.00 36.14  ? 169 TYR B CE2 1 
ATOM   4621  C  CZ  . TYR B 2 171 ? 268.169 275.320 285.599 1.00 39.63  ? 169 TYR B CZ  1 
ATOM   4622  O  OH  . TYR B 2 171 ? 267.054 274.832 286.236 1.00 41.08  ? 169 TYR B OH  1 
ATOM   4623  N  N   . TYR B 2 172 ? 274.718 276.715 284.417 1.00 31.58  ? 170 TYR B N   1 
ATOM   4624  C  CA  . TYR B 2 172 ? 276.018 276.375 283.853 1.00 28.54  ? 170 TYR B CA  1 
ATOM   4625  C  C   . TYR B 2 172 ? 275.847 275.174 282.934 1.00 30.12  ? 170 TYR B C   1 
ATOM   4626  O  O   . TYR B 2 172 ? 275.453 274.095 283.388 1.00 34.75  ? 170 TYR B O   1 
ATOM   4627  C  CB  . TYR B 2 172 ? 277.033 276.056 284.950 1.00 29.54  ? 170 TYR B CB  1 
ATOM   4628  C  CG  . TYR B 2 172 ? 277.701 277.260 285.566 1.00 31.85  ? 170 TYR B CG  1 
ATOM   4629  C  CD1 . TYR B 2 172 ? 277.967 278.394 284.812 1.00 30.02  ? 170 TYR B CD1 1 
ATOM   4630  C  CD2 . TYR B 2 172 ? 278.071 277.259 286.902 1.00 33.17  ? 170 TYR B CD2 1 
ATOM   4631  C  CE1 . TYR B 2 172 ? 278.582 279.492 285.373 1.00 31.39  ? 170 TYR B CE1 1 
ATOM   4632  C  CE2 . TYR B 2 172 ? 278.685 278.352 287.472 1.00 34.38  ? 170 TYR B CE2 1 
ATOM   4633  C  CZ  . TYR B 2 172 ? 278.938 279.466 286.704 1.00 33.41  ? 170 TYR B CZ  1 
ATOM   4634  O  OH  . TYR B 2 172 ? 279.551 280.558 287.271 1.00 39.49  ? 170 TYR B OH  1 
ATOM   4635  N  N   . VAL B 2 173 ? 276.148 275.355 281.653 1.00 26.84  ? 171 VAL B N   1 
ATOM   4636  C  CA  . VAL B 2 173 ? 276.009 274.298 280.660 1.00 29.54  ? 171 VAL B CA  1 
ATOM   4637  C  C   . VAL B 2 173 ? 277.402 273.892 280.204 1.00 31.66  ? 171 VAL B C   1 
ATOM   4638  O  O   . VAL B 2 173 ? 278.174 274.726 279.715 1.00 30.55  ? 171 VAL B O   1 
ATOM   4639  C  CB  . VAL B 2 173 ? 275.141 274.744 279.474 1.00 34.16  ? 171 VAL B CB  1 
ATOM   4640  C  CG1 . VAL B 2 173 ? 274.930 273.589 278.512 1.00 30.04  ? 171 VAL B CG1 1 
ATOM   4641  C  CG2 . VAL B 2 173 ? 273.809 275.276 279.970 1.00 32.79  ? 171 VAL B CG2 1 
ATOM   4642  N  N   . LYS B 2 174 ? 277.724 272.613 280.367 1.00 32.40  ? 172 LYS B N   1 
ATOM   4643  C  CA  . LYS B 2 174 ? 279.008 272.060 279.958 1.00 28.14  ? 172 LYS B CA  1 
ATOM   4644  C  C   . LYS B 2 174 ? 278.812 271.339 278.631 1.00 28.19  ? 172 LYS B C   1 
ATOM   4645  O  O   . LYS B 2 174 ? 278.242 270.244 278.591 1.00 30.67  ? 172 LYS B O   1 
ATOM   4646  C  CB  . LYS B 2 174 ? 279.554 271.118 281.028 1.00 28.36  ? 172 LYS B CB  1 
ATOM   4647  C  CG  . LYS B 2 174 ? 281.001 270.715 280.827 1.00 33.60  ? 172 LYS B CG  1 
ATOM   4648  C  CD  . LYS B 2 174 ? 281.376 269.569 281.746 1.00 32.80  ? 172 LYS B CD  1 
ATOM   4649  C  CE  . LYS B 2 174 ? 282.878 269.348 281.772 1.00 37.51  ? 172 LYS B CE  1 
ATOM   4650  N  NZ  . LYS B 2 174 ? 283.224 267.931 282.065 1.00 40.36  ? 172 LYS B NZ  1 
ATOM   4651  N  N   . GLU B 2 175 ? 279.276 271.954 277.549 1.00 30.23  ? 173 GLU B N   1 
ATOM   4652  C  CA  . GLU B 2 175 ? 279.128 271.414 276.210 1.00 32.19  ? 173 GLU B CA  1 
ATOM   4653  C  C   . GLU B 2 175 ? 280.453 270.852 275.719 1.00 32.39  ? 173 GLU B C   1 
ATOM   4654  O  O   . GLU B 2 175 ? 281.529 271.286 276.135 1.00 36.26  ? 173 GLU B O   1 
ATOM   4655  C  CB  . GLU B 2 175 ? 278.650 272.479 275.221 1.00 33.04  ? 173 GLU B CB  1 
ATOM   4656  C  CG  . GLU B 2 175 ? 277.920 273.649 275.834 1.00 33.86  ? 173 GLU B CG  1 
ATOM   4657  C  CD  . GLU B 2 175 ? 277.594 274.709 274.805 1.00 40.30  ? 173 GLU B CD  1 
ATOM   4658  O  OE1 . GLU B 2 175 ? 278.424 274.926 273.898 1.00 33.79  ? 173 GLU B OE1 1 
ATOM   4659  O  OE2 . GLU B 2 175 ? 276.510 275.318 274.895 1.00 46.76  ? 173 GLU B OE2 1 
ATOM   4660  N  N   . GLU B 2 176 ? 280.352 269.889 274.812 1.00 35.34  ? 174 GLU B N   1 
ATOM   4661  C  CA  . GLU B 2 176 ? 281.500 269.290 274.145 1.00 30.70  ? 174 GLU B CA  1 
ATOM   4662  C  C   . GLU B 2 176 ? 281.243 269.364 272.647 1.00 33.18  ? 174 GLU B C   1 
ATOM   4663  O  O   . GLU B 2 176 ? 280.361 268.668 272.132 1.00 35.36  ? 174 GLU B O   1 
ATOM   4664  C  CB  . GLU B 2 176 ? 281.706 267.847 274.599 1.00 34.43  ? 174 GLU B CB  1 
ATOM   4665  C  CG  . GLU B 2 176 ? 282.735 267.076 273.806 1.00 41.11  ? 174 GLU B CG  1 
ATOM   4666  C  CD  . GLU B 2 176 ? 282.810 265.627 274.232 1.00 53.64  ? 174 GLU B CD  1 
ATOM   4667  O  OE1 . GLU B 2 176 ? 281.826 265.134 274.820 1.00 54.11  ? 174 GLU B OE1 1 
ATOM   4668  O  OE2 . GLU B 2 176 ? 283.845 264.980 273.979 1.00 55.01  ? 174 GLU B OE2 1 
ATOM   4669  N  N   . TRP B 2 177 ? 281.973 270.239 271.964 1.00 30.91  ? 175 TRP B N   1 
ATOM   4670  C  CA  . TRP B 2 177 ? 281.979 270.255 270.511 1.00 27.07  ? 175 TRP B CA  1 
ATOM   4671  C  C   . TRP B 2 177 ? 282.919 269.164 270.023 1.00 30.68  ? 175 TRP B C   1 
ATOM   4672  O  O   . TRP B 2 177 ? 284.034 269.024 270.534 1.00 36.24  ? 175 TRP B O   1 
ATOM   4673  C  CB  . TRP B 2 177 ? 282.432 271.617 269.983 1.00 28.74  ? 175 TRP B CB  1 
ATOM   4674  C  CG  . TRP B 2 177 ? 281.568 272.779 270.386 1.00 28.79  ? 175 TRP B CG  1 
ATOM   4675  C  CD1 . TRP B 2 177 ? 281.135 273.088 271.642 1.00 29.22  ? 175 TRP B CD1 1 
ATOM   4676  C  CD2 . TRP B 2 177 ? 281.058 273.802 269.524 1.00 28.29  ? 175 TRP B CD2 1 
ATOM   4677  N  NE1 . TRP B 2 177 ? 280.377 274.231 271.613 1.00 29.01  ? 175 TRP B NE1 1 
ATOM   4678  C  CE2 . TRP B 2 177 ? 280.316 274.690 270.324 1.00 27.82  ? 175 TRP B CE2 1 
ATOM   4679  C  CE3 . TRP B 2 177 ? 281.154 274.049 268.152 1.00 30.88  ? 175 TRP B CE3 1 
ATOM   4680  C  CZ2 . TRP B 2 177 ? 279.673 275.807 269.798 1.00 30.93  ? 175 TRP B CZ2 1 
ATOM   4681  C  CZ3 . TRP B 2 177 ? 280.516 275.157 267.633 1.00 32.94  ? 175 TRP B CZ3 1 
ATOM   4682  C  CH2 . TRP B 2 177 ? 279.785 276.022 268.453 1.00 34.78  ? 175 TRP B CH2 1 
ATOM   4683  N  N   . TYR B 2 178 ? 282.470 268.389 269.041 1.00 30.28  ? 176 TYR B N   1 
ATOM   4684  C  CA  . TYR B 2 178 ? 283.263 267.277 268.546 1.00 28.09  ? 176 TYR B CA  1 
ATOM   4685  C  C   . TYR B 2 178 ? 283.085 267.138 267.043 1.00 27.90  ? 176 TYR B C   1 
ATOM   4686  O  O   . TYR B 2 178 ? 282.078 267.559 266.465 1.00 31.77  ? 176 TYR B O   1 
ATOM   4687  C  CB  . TYR B 2 178 ? 282.899 265.960 269.247 1.00 31.67  ? 176 TYR B CB  1 
ATOM   4688  C  CG  . TYR B 2 178 ? 281.479 265.500 269.016 1.00 32.58  ? 176 TYR B CG  1 
ATOM   4689  C  CD1 . TYR B 2 178 ? 280.432 266.014 269.767 1.00 33.53  ? 176 TYR B CD1 1 
ATOM   4690  C  CD2 . TYR B 2 178 ? 281.187 264.545 268.053 1.00 33.02  ? 176 TYR B CD2 1 
ATOM   4691  C  CE1 . TYR B 2 178 ? 279.135 265.594 269.561 1.00 35.97  ? 176 TYR B CE1 1 
ATOM   4692  C  CE2 . TYR B 2 178 ? 279.894 264.119 267.840 1.00 39.30  ? 176 TYR B CE2 1 
ATOM   4693  C  CZ  . TYR B 2 178 ? 278.872 264.646 268.597 1.00 39.11  ? 176 TYR B CZ  1 
ATOM   4694  O  OH  . TYR B 2 178 ? 277.581 264.225 268.389 1.00 39.99  ? 176 TYR B OH  1 
ATOM   4695  N  N   . PHE B 2 179 ? 284.094 266.536 266.422 1.00 27.58  ? 177 PHE B N   1 
ATOM   4696  C  CA  . PHE B 2 179 ? 284.109 266.233 264.998 1.00 28.97  ? 177 PHE B CA  1 
ATOM   4697  C  C   . PHE B 2 179 ? 283.869 264.739 264.831 1.00 30.53  ? 177 PHE B C   1 
ATOM   4698  O  O   . PHE B 2 179 ? 284.606 263.923 265.393 1.00 33.93  ? 177 PHE B O   1 
ATOM   4699  C  CB  . PHE B 2 179 ? 285.443 266.649 264.376 1.00 28.77  ? 177 PHE B CB  1 
ATOM   4700  C  CG  . PHE B 2 179 ? 285.479 266.549 262.879 1.00 30.99  ? 177 PHE B CG  1 
ATOM   4701  C  CD1 . PHE B 2 179 ? 284.856 267.500 262.092 1.00 30.45  ? 177 PHE B CD1 1 
ATOM   4702  C  CD2 . PHE B 2 179 ? 286.154 265.512 262.258 1.00 29.38  ? 177 PHE B CD2 1 
ATOM   4703  C  CE1 . PHE B 2 179 ? 284.893 267.412 260.716 1.00 28.26  ? 177 PHE B CE1 1 
ATOM   4704  C  CE2 . PHE B 2 179 ? 286.195 265.420 260.885 1.00 25.97  ? 177 PHE B CE2 1 
ATOM   4705  C  CZ  . PHE B 2 179 ? 285.564 266.372 260.113 1.00 25.36  ? 177 PHE B CZ  1 
ATOM   4706  N  N   . THR B 2 180 ? 282.844 264.388 264.071 1.00 33.31  ? 178 THR B N   1 
ATOM   4707  C  CA  . THR B 2 180 ? 282.486 262.985 263.905 1.00 33.21  ? 178 THR B CA  1 
ATOM   4708  C  C   . THR B 2 180 ? 283.458 262.313 262.942 1.00 35.18  ? 178 THR B C   1 
ATOM   4709  O  O   . THR B 2 180 ? 283.627 262.784 261.813 1.00 34.38  ? 178 THR B O   1 
ATOM   4710  C  CB  . THR B 2 180 ? 281.058 262.849 263.387 1.00 35.93  ? 178 THR B CB  1 
ATOM   4711  O  OG1 . THR B 2 180 ? 280.140 262.965 264.481 1.00 36.42  ? 178 THR B OG1 1 
ATOM   4712  C  CG2 . THR B 2 180 ? 280.862 261.502 262.715 1.00 41.73  ? 178 THR B CG2 1 
ATOM   4713  N  N   . PRO B 2 181 ? 284.112 261.222 263.346 1.00 37.04  ? 179 PRO B N   1 
ATOM   4714  C  CA  . PRO B 2 181 ? 285.107 260.612 262.450 1.00 37.81  ? 179 PRO B CA  1 
ATOM   4715  C  C   . PRO B 2 181 ? 284.495 259.985 261.211 1.00 41.29  ? 179 PRO B C   1 
ATOM   4716  O  O   . PRO B 2 181 ? 285.029 260.159 260.109 1.00 41.59  ? 179 PRO B O   1 
ATOM   4717  C  CB  . PRO B 2 181 ? 285.787 259.568 263.346 1.00 34.45  ? 179 PRO B CB  1 
ATOM   4718  C  CG  . PRO B 2 181 ? 284.768 259.243 264.385 1.00 38.00  ? 179 PRO B CG  1 
ATOM   4719  C  CD  . PRO B 2 181 ? 283.998 260.506 264.629 1.00 36.05  ? 179 PRO B CD  1 
ATOM   4720  N  N   . THR B 2 182 ? 283.383 259.262 261.353 1.00 35.62  ? 180 THR B N   1 
ATOM   4721  C  CA  . THR B 2 182 ? 282.793 258.575 260.209 1.00 32.94  ? 180 THR B CA  1 
ATOM   4722  C  C   . THR B 2 182 ? 282.037 259.532 259.294 1.00 36.52  ? 180 THR B C   1 
ATOM   4723  O  O   . THR B 2 182 ? 282.045 259.357 258.071 1.00 36.31  ? 180 THR B O   1 
ATOM   4724  C  CB  . THR B 2 182 ? 281.858 257.463 260.685 1.00 37.25  ? 180 THR B CB  1 
ATOM   4725  O  OG1 . THR B 2 182 ? 280.836 258.022 261.518 1.00 47.07  ? 180 THR B OG1 1 
ATOM   4726  C  CG2 . THR B 2 182 ? 282.628 256.417 261.471 1.00 34.50  ? 180 THR B CG2 1 
ATOM   4727  N  N   . ASN B 2 183 ? 281.379 260.540 259.862 1.00 40.56  ? 181 ASN B N   1 
ATOM   4728  C  CA  . ASN B 2 183 ? 280.512 261.427 259.096 1.00 36.52  ? 181 ASN B CA  1 
ATOM   4729  C  C   . ASN B 2 183 ? 281.186 262.723 258.673 1.00 37.27  ? 181 ASN B C   1 
ATOM   4730  O  O   . ASN B 2 183 ? 280.784 263.315 257.667 1.00 33.73  ? 181 ASN B O   1 
ATOM   4731  C  CB  . ASN B 2 183 ? 279.253 261.759 259.904 1.00 35.09  ? 181 ASN B CB  1 
ATOM   4732  C  CG  . ASN B 2 183 ? 277.992 261.673 259.076 1.00 42.52  ? 181 ASN B CG  1 
ATOM   4733  O  OD1 . ASN B 2 183 ? 277.919 260.906 258.117 1.00 47.81  ? 181 ASN B OD1 1 
ATOM   4734  N  ND2 . ASN B 2 183 ? 276.990 262.465 259.437 1.00 42.23  ? 181 ASN B ND2 1 
ATOM   4735  N  N   . SER B 2 184 ? 282.193 263.183 259.416 1.00 37.82  ? 182 SER B N   1 
ATOM   4736  C  CA  . SER B 2 184 ? 282.921 264.407 259.081 1.00 31.70  ? 182 SER B CA  1 
ATOM   4737  C  C   . SER B 2 184 ? 282.050 265.650 259.263 1.00 34.69  ? 182 SER B C   1 
ATOM   4738  O  O   . SER B 2 184 ? 282.042 266.544 258.416 1.00 39.20  ? 182 SER B O   1 
ATOM   4739  C  CB  . SER B 2 184 ? 283.483 264.347 257.658 1.00 26.40  ? 182 SER B CB  1 
ATOM   4740  O  OG  . SER B 2 184 ? 284.697 263.620 257.615 1.00 32.63  ? 182 SER B OG  1 
ATOM   4741  N  N   . ASP B 2 185 ? 281.311 265.710 260.368 1.00 31.16  ? 183 ASP B N   1 
ATOM   4742  C  CA  . ASP B 2 185 ? 280.501 266.874 260.696 1.00 35.99  ? 183 ASP B CA  1 
ATOM   4743  C  C   . ASP B 2 185 ? 280.691 267.232 262.162 1.00 35.30  ? 183 ASP B C   1 
ATOM   4744  O  O   . ASP B 2 185 ? 281.024 266.380 262.988 1.00 34.41  ? 183 ASP B O   1 
ATOM   4745  C  CB  . ASP B 2 185 ? 279.002 266.653 260.411 1.00 36.94  ? 183 ASP B CB  1 
ATOM   4746  C  CG  . ASP B 2 185 ? 278.538 265.238 260.704 1.00 40.08  ? 183 ASP B CG  1 
ATOM   4747  O  OD1 . ASP B 2 185 ? 279.347 264.400 261.150 1.00 45.29  ? 183 ASP B OD1 1 
ATOM   4748  O  OD2 . ASP B 2 185 ? 277.343 264.961 260.481 1.00 41.47  ? 183 ASP B OD2 1 
ATOM   4749  N  N   . VAL B 2 186 ? 280.473 268.501 262.475 1.00 31.93  ? 184 VAL B N   1 
ATOM   4750  C  CA  . VAL B 2 186 ? 280.655 269.015 263.827 1.00 32.16  ? 184 VAL B CA  1 
ATOM   4751  C  C   . VAL B 2 186 ? 279.332 268.952 264.573 1.00 34.97  ? 184 VAL B C   1 
ATOM   4752  O  O   . VAL B 2 186 ? 278.267 269.224 264.008 1.00 38.69  ? 184 VAL B O   1 
ATOM   4753  C  CB  . VAL B 2 186 ? 281.210 270.450 263.799 1.00 33.66  ? 184 VAL B CB  1 
ATOM   4754  C  CG1 . VAL B 2 186 ? 281.508 270.926 265.210 1.00 34.24  ? 184 VAL B CG1 1 
ATOM   4755  C  CG2 . VAL B 2 186 ? 282.458 270.510 262.943 1.00 34.99  ? 184 VAL B CG2 1 
ATOM   4756  N  N   . ASP B 2 187 ? 279.398 268.587 265.851 1.00 32.75  ? 185 ASP B N   1 
ATOM   4757  C  CA  . ASP B 2 187 ? 278.201 268.502 266.673 1.00 30.74  ? 185 ASP B CA  1 
ATOM   4758  C  C   . ASP B 2 187 ? 278.531 268.919 268.097 1.00 31.90  ? 185 ASP B C   1 
ATOM   4759  O  O   . ASP B 2 187 ? 279.696 268.991 268.492 1.00 33.71  ? 185 ASP B O   1 
ATOM   4760  C  CB  . ASP B 2 187 ? 277.598 267.094 266.651 1.00 36.34  ? 185 ASP B CB  1 
ATOM   4761  C  CG  . ASP B 2 187 ? 276.084 267.108 266.724 1.00 43.85  ? 185 ASP B CG  1 
ATOM   4762  O  OD1 . ASP B 2 187 ? 275.518 268.146 267.125 1.00 47.12  ? 185 ASP B OD1 1 
ATOM   4763  O  OD2 . ASP B 2 187 ? 275.460 266.084 266.378 1.00 48.89  ? 185 ASP B OD2 1 
ATOM   4764  N  N   . ILE B 2 188 ? 277.482 269.210 268.861 1.00 34.51  ? 186 ILE B N   1 
ATOM   4765  C  CA  . ILE B 2 188 ? 277.598 269.627 270.253 1.00 34.17  ? 186 ILE B CA  1 
ATOM   4766  C  C   . ILE B 2 188 ? 276.854 268.619 271.116 1.00 35.22  ? 186 ILE B C   1 
ATOM   4767  O  O   . ILE B 2 188 ? 275.723 268.236 270.796 1.00 38.43  ? 186 ILE B O   1 
ATOM   4768  C  CB  . ILE B 2 188 ? 277.044 271.046 270.472 1.00 34.11  ? 186 ILE B CB  1 
ATOM   4769  C  CG1 . ILE B 2 188 ? 277.701 272.031 269.505 1.00 33.72  ? 186 ILE B CG1 1 
ATOM   4770  C  CG2 . ILE B 2 188 ? 277.269 271.488 271.906 1.00 31.10  ? 186 ILE B CG2 1 
ATOM   4771  C  CD1 . ILE B 2 188 ? 277.054 273.397 269.499 1.00 34.04  ? 186 ILE B CD1 1 
ATOM   4772  N  N   . LYS B 2 189 ? 277.489 268.192 272.202 1.00 32.70  ? 187 LYS B N   1 
ATOM   4773  C  CA  . LYS B 2 189 ? 276.899 267.263 273.154 1.00 28.95  ? 187 LYS B CA  1 
ATOM   4774  C  C   . LYS B 2 189 ? 276.872 267.901 274.534 1.00 34.51  ? 187 LYS B C   1 
ATOM   4775  O  O   . LYS B 2 189 ? 277.824 268.574 274.932 1.00 36.92  ? 187 LYS B O   1 
ATOM   4776  C  CB  . LYS B 2 189 ? 277.689 265.954 273.196 1.00 31.08  ? 187 LYS B CB  1 
ATOM   4777  C  CG  . LYS B 2 189 ? 276.981 264.810 273.886 1.00 37.05  ? 187 LYS B CG  1 
ATOM   4778  C  CD  . LYS B 2 189 ? 277.961 263.696 274.198 1.00 45.51  ? 187 LYS B CD  1 
ATOM   4779  C  CE  . LYS B 2 189 ? 277.498 262.851 275.369 1.00 47.12  ? 187 LYS B CE  1 
ATOM   4780  N  NZ  . LYS B 2 189 ? 276.258 262.094 275.053 1.00 52.62  ? 187 LYS B NZ  1 
ATOM   4781  N  N   . ILE B 2 190 ? 275.784 267.696 275.266 1.00 36.66  ? 188 ILE B N   1 
ATOM   4782  C  CA  . ILE B 2 190 ? 275.642 268.258 276.604 1.00 31.67  ? 188 ILE B CA  1 
ATOM   4783  C  C   . ILE B 2 190 ? 276.121 267.234 277.621 1.00 34.60  ? 188 ILE B C   1 
ATOM   4784  O  O   . ILE B 2 190 ? 275.693 266.074 277.601 1.00 41.47  ? 188 ILE B O   1 
ATOM   4785  C  CB  . ILE B 2 190 ? 274.188 268.675 276.881 1.00 35.52  ? 188 ILE B CB  1 
ATOM   4786  C  CG1 . ILE B 2 190 ? 273.641 269.500 275.717 1.00 34.96  ? 188 ILE B CG1 1 
ATOM   4787  C  CG2 . ILE B 2 190 ? 274.102 269.470 278.173 1.00 32.02  ? 188 ILE B CG2 1 
ATOM   4788  C  CD1 . ILE B 2 190 ? 273.827 270.985 275.887 1.00 31.87  ? 188 ILE B CD1 1 
ATOM   4789  N  N   . GLN B 2 191 ? 277.011 267.662 278.513 1.00 31.84  ? 189 GLN B N   1 
ATOM   4790  C  CA  . GLN B 2 191 ? 277.565 266.793 279.543 1.00 31.11  ? 189 GLN B CA  1 
ATOM   4791  C  C   . GLN B 2 191 ? 276.907 266.983 280.901 1.00 33.93  ? 189 GLN B C   1 
ATOM   4792  O  O   . GLN B 2 191 ? 276.572 265.997 281.563 1.00 41.74  ? 189 GLN B O   1 
ATOM   4793  C  CB  . GLN B 2 191 ? 279.073 267.029 279.676 1.00 33.78  ? 189 GLN B CB  1 
ATOM   4794  C  CG  . GLN B 2 191 ? 279.792 267.223 278.355 1.00 34.18  ? 189 GLN B CG  1 
ATOM   4795  C  CD  . GLN B 2 191 ? 280.553 265.989 277.926 1.00 43.08  ? 189 GLN B CD  1 
ATOM   4796  O  OE1 . GLN B 2 191 ? 279.961 264.963 277.596 1.00 45.83  ? 189 GLN B OE1 1 
ATOM   4797  N  NE2 . GLN B 2 191 ? 281.877 266.082 277.932 1.00 48.05  ? 189 GLN B NE2 1 
ATOM   4798  N  N   . ALA B 2 192 ? 276.720 268.226 281.336 1.00 33.53  ? 190 ALA B N   1 
ATOM   4799  C  CA  . ALA B 2 192 ? 276.132 268.490 282.640 1.00 33.95  ? 190 ALA B CA  1 
ATOM   4800  C  C   . ALA B 2 192 ? 275.590 269.910 282.666 1.00 34.40  ? 190 ALA B C   1 
ATOM   4801  O  O   . ALA B 2 192 ? 275.947 270.747 281.833 1.00 35.18  ? 190 ALA B O   1 
ATOM   4802  C  CB  . ALA B 2 192 ? 277.151 268.280 283.765 1.00 35.20  ? 190 ALA B CB  1 
ATOM   4803  N  N   . ILE B 2 193 ? 274.717 270.167 283.636 1.00 32.38  ? 191 ILE B N   1 
ATOM   4804  C  CA  . ILE B 2 193 ? 274.139 271.488 283.852 1.00 29.83  ? 191 ILE B CA  1 
ATOM   4805  C  C   . ILE B 2 193 ? 274.111 271.760 285.348 1.00 35.08  ? 191 ILE B C   1 
ATOM   4806  O  O   . ILE B 2 193 ? 273.815 270.866 286.147 1.00 39.63  ? 191 ILE B O   1 
ATOM   4807  C  CB  . ILE B 2 193 ? 272.725 271.602 283.245 1.00 33.67  ? 191 ILE B CB  1 
ATOM   4808  C  CG1 . ILE B 2 193 ? 271.775 270.602 283.908 1.00 35.18  ? 191 ILE B CG1 1 
ATOM   4809  C  CG2 . ILE B 2 193 ? 272.772 271.382 281.744 1.00 30.58  ? 191 ILE B CG2 1 
ATOM   4810  C  CD1 . ILE B 2 193 ? 270.312 270.895 283.667 1.00 30.15  ? 191 ILE B CD1 1 
ATOM   4811  N  N   . CYS B 2 194 ? 274.426 272.993 285.727 1.00 33.43  ? 192 CYS B N   1 
ATOM   4812  C  CA  . CYS B 2 194 ? 274.467 273.391 287.134 1.00 33.03  ? 192 CYS B CA  1 
ATOM   4813  C  C   . CYS B 2 194 ? 273.540 274.571 287.377 1.00 35.07  ? 192 CYS B C   1 
ATOM   4814  O  O   . CYS B 2 194 ? 273.785 275.668 286.839 1.00 35.75  ? 192 CYS B O   1 
ATOM   4815  C  CB  . CYS B 2 194 ? 275.894 273.745 287.552 1.00 32.54  ? 192 CYS B CB  1 
ATOM   4816  S  SG  . CYS B 2 194 ? 276.030 274.465 289.201 1.00 43.12  ? 192 CYS B SG  1 
ATOM   4817  N  N   . PRO B 2 195 ? 272.478 274.413 288.164 1.00 37.56  ? 193 PRO B N   1 
ATOM   4818  C  CA  . PRO B 2 195 ? 271.636 275.567 288.496 1.00 37.09  ? 193 PRO B CA  1 
ATOM   4819  C  C   . PRO B 2 195 ? 272.368 276.524 289.421 1.00 42.09  ? 193 PRO B C   1 
ATOM   4820  O  O   . PRO B 2 195 ? 273.035 276.111 290.372 1.00 43.74  ? 193 PRO B O   1 
ATOM   4821  C  CB  . PRO B 2 195 ? 270.418 274.940 289.189 1.00 35.37  ? 193 PRO B CB  1 
ATOM   4822  C  CG  . PRO B 2 195 ? 270.563 273.453 289.020 1.00 36.82  ? 193 PRO B CG  1 
ATOM   4823  C  CD  . PRO B 2 195 ? 272.010 273.180 288.811 1.00 37.36  ? 193 PRO B CD  1 
ATOM   4824  N  N   . ILE B 2 196 ? 272.236 277.816 289.136 1.00 42.27  ? 194 ILE B N   1 
ATOM   4825  C  CA  . ILE B 2 196 ? 272.868 278.867 289.924 1.00 45.74  ? 194 ILE B CA  1 
ATOM   4826  C  C   . ILE B 2 196 ? 271.772 279.648 290.634 1.00 46.12  ? 194 ILE B C   1 
ATOM   4827  O  O   . ILE B 2 196 ? 270.909 280.252 289.985 1.00 43.38  ? 194 ILE B O   1 
ATOM   4828  C  CB  . ILE B 2 196 ? 273.729 279.794 289.053 1.00 44.24  ? 194 ILE B CB  1 
ATOM   4829  C  CG1 . ILE B 2 196 ? 274.717 278.983 288.212 1.00 37.04  ? 194 ILE B CG1 1 
ATOM   4830  C  CG2 . ILE B 2 196 ? 274.467 280.801 289.917 1.00 47.45  ? 194 ILE B CG2 1 
ATOM   4831  C  CD1 . ILE B 2 196 ? 275.035 279.617 286.877 1.00 33.82  ? 194 ILE B CD1 1 
ATOM   4832  N  N   . MET B 2 197 ? 271.804 279.635 291.963 1.00 48.19  ? 195 MET B N   1 
ATOM   4833  C  CA  . MET B 2 197 ? 270.872 280.430 292.747 1.00 52.61  ? 195 MET B CA  1 
ATOM   4834  C  C   . MET B 2 197 ? 271.330 281.882 292.780 1.00 58.47  ? 195 MET B C   1 
ATOM   4835  O  O   . MET B 2 197 ? 272.514 282.172 292.971 1.00 60.88  ? 195 MET B O   1 
ATOM   4836  C  CB  . MET B 2 197 ? 270.755 279.879 294.167 1.00 54.26  ? 195 MET B CB  1 
ATOM   4837  C  CG  . MET B 2 197 ? 269.889 280.721 295.086 1.00 64.18  ? 195 MET B CG  1 
ATOM   4838  S  SD  . MET B 2 197 ? 268.690 279.740 296.003 1.00 81.87  ? 195 MET B SD  1 
ATOM   4839  C  CE  . MET B 2 197 ? 269.747 278.981 297.232 1.00 65.92  ? 195 MET B CE  1 
ATOM   4840  N  N   . THR B 2 198 ? 270.381 282.796 292.597 1.00 59.28  ? 196 THR B N   1 
ATOM   4841  C  CA  . THR B 2 198 ? 270.704 284.213 292.500 1.00 67.18  ? 196 THR B CA  1 
ATOM   4842  C  C   . THR B 2 198 ? 270.106 284.974 293.675 1.00 75.41  ? 196 THR B C   1 
ATOM   4843  O  O   . THR B 2 198 ? 269.528 286.052 293.499 1.00 79.61  ? 196 THR B O   1 
ATOM   4844  C  CB  . THR B 2 198 ? 270.203 284.790 291.173 1.00 69.21  ? 196 THR B CB  1 
ATOM   4845  O  OG1 . THR B 2 198 ? 270.675 283.979 290.090 1.00 64.25  ? 196 THR B OG1 1 
ATOM   4846  C  CG2 . THR B 2 198 ? 270.712 286.209 290.983 1.00 66.70  ? 196 THR B CG2 1 
ATOM   4847  N  N   . GLY B 2 199 ? 270.238 284.421 294.877 1.00 75.77  ? 197 GLY B N   1 
ATOM   4848  C  CA  . GLY B 2 199 ? 269.678 285.043 296.060 1.00 88.57  ? 197 GLY B CA  1 
ATOM   4849  C  C   . GLY B 2 199 ? 270.341 286.358 296.412 1.00 103.41 ? 197 GLY B C   1 
ATOM   4850  O  O   . GLY B 2 199 ? 271.029 286.956 295.579 1.00 101.00 ? 197 GLY B O   1 
ATOM   4851  N  N   . GLN B 2 200 ? 270.146 286.820 297.643 1.00 110.27 ? 198 GLN B N   1 
ATOM   4852  C  CA  . GLN B 2 200 ? 270.638 288.117 298.088 1.00 115.45 ? 198 GLN B CA  1 
ATOM   4853  C  C   . GLN B 2 200 ? 271.859 287.910 298.974 1.00 119.16 ? 198 GLN B C   1 
ATOM   4854  O  O   . GLN B 2 200 ? 271.786 287.198 299.981 1.00 118.08 ? 198 GLN B O   1 
ATOM   4855  C  CB  . GLN B 2 200 ? 269.554 288.886 298.843 1.00 113.12 ? 198 GLN B CB  1 
ATOM   4856  C  CG  . GLN B 2 200 ? 269.670 290.397 298.728 1.00 116.66 ? 198 GLN B CG  1 
ATOM   4857  C  CD  . GLN B 2 200 ? 269.318 290.904 297.344 1.00 119.63 ? 198 GLN B CD  1 
ATOM   4858  O  OE1 . GLN B 2 200 ? 270.161 291.459 296.639 1.00 115.08 ? 198 GLN B OE1 1 
ATOM   4859  N  NE2 . GLN B 2 200 ? 268.064 290.719 296.948 1.00 123.56 ? 198 GLN B NE2 1 
ATOM   4860  N  N   . ASP B 2 201 ? 272.972 288.535 298.599 1.00 119.40 ? 199 ASP B N   1 
ATOM   4861  C  CA  . ASP B 2 201 ? 274.185 288.437 299.398 1.00 121.15 ? 199 ASP B CA  1 
ATOM   4862  C  C   . ASP B 2 201 ? 273.947 289.015 300.786 1.00 126.88 ? 199 ASP B C   1 
ATOM   4863  O  O   . ASP B 2 201 ? 273.359 290.091 300.932 1.00 126.71 ? 199 ASP B O   1 
ATOM   4864  C  CB  . ASP B 2 201 ? 275.336 289.171 298.708 1.00 119.95 ? 199 ASP B CB  1 
ATOM   4865  C  CG  . ASP B 2 201 ? 276.693 288.776 299.258 1.00 120.85 ? 199 ASP B CG  1 
ATOM   4866  O  OD1 . ASP B 2 201 ? 276.737 287.983 300.222 1.00 119.78 ? 199 ASP B OD1 1 
ATOM   4867  O  OD2 . ASP B 2 201 ? 277.715 289.260 298.728 1.00 118.12 ? 199 ASP B OD2 1 
ATOM   4868  N  N   . GLU B 2 202 ? 274.404 288.296 301.807 1.00 128.00 ? 200 GLU B N   1 
ATOM   4869  C  CA  . GLU B 2 202 ? 274.277 288.790 303.169 1.00 129.35 ? 200 GLU B CA  1 
ATOM   4870  C  C   . GLU B 2 202 ? 275.046 290.096 303.324 1.00 131.66 ? 200 GLU B C   1 
ATOM   4871  O  O   . GLU B 2 202 ? 276.067 290.325 302.670 1.00 131.36 ? 200 GLU B O   1 
ATOM   4872  C  CB  . GLU B 2 202 ? 274.786 287.751 304.169 1.00 127.69 ? 200 GLU B CB  1 
ATOM   4873  C  CG  . GLU B 2 202 ? 273.782 286.655 304.489 1.00 127.86 ? 200 GLU B CG  1 
ATOM   4874  C  CD  . GLU B 2 202 ? 273.768 286.288 305.961 1.00 125.59 ? 200 GLU B CD  1 
ATOM   4875  O  OE1 . GLU B 2 202 ? 274.858 286.187 306.561 1.00 123.82 ? 200 GLU B OE1 1 
ATOM   4876  O  OE2 . GLU B 2 202 ? 272.665 286.102 306.518 1.00 122.73 ? 200 GLU B OE2 1 
ATOM   4877  N  N   . PHE B 2 203 ? 274.542 290.961 304.202 1.00 131.83 ? 201 PHE B N   1 
ATOM   4878  C  CA  . PHE B 2 203 ? 275.090 292.291 304.453 1.00 132.73 ? 201 PHE B CA  1 
ATOM   4879  C  C   . PHE B 2 203 ? 274.939 293.215 303.253 1.00 131.23 ? 201 PHE B C   1 
ATOM   4880  O  O   . PHE B 2 203 ? 275.650 294.224 303.163 1.00 129.41 ? 201 PHE B O   1 
ATOM   4881  C  CB  . PHE B 2 203 ? 276.567 292.234 304.865 1.00 132.82 ? 201 PHE B CB  1 
ATOM   4882  C  CG  . PHE B 2 203 ? 276.955 290.969 305.580 1.00 133.43 ? 201 PHE B CG  1 
ATOM   4883  C  CD1 . PHE B 2 203 ? 276.246 290.535 306.688 1.00 132.10 ? 201 PHE B CD1 1 
ATOM   4884  C  CD2 . PHE B 2 203 ? 278.024 290.210 305.137 1.00 131.54 ? 201 PHE B CD2 1 
ATOM   4885  C  CE1 . PHE B 2 203 ? 276.600 289.370 307.342 1.00 132.87 ? 201 PHE B CE1 1 
ATOM   4886  C  CE2 . PHE B 2 203 ? 278.383 289.045 305.786 1.00 130.22 ? 201 PHE B CE2 1 
ATOM   4887  C  CZ  . PHE B 2 203 ? 277.671 288.624 306.890 1.00 132.37 ? 201 PHE B CZ  1 
ATOM   4888  N  N   . GLY B 2 204 ? 274.039 292.905 302.332 1.00 129.64 ? 202 GLY B N   1 
ATOM   4889  C  CA  . GLY B 2 204 ? 273.844 293.685 301.128 1.00 126.02 ? 202 GLY B CA  1 
ATOM   4890  C  C   . GLY B 2 204 ? 274.476 293.024 299.914 1.00 126.11 ? 202 GLY B C   1 
ATOM   4891  O  O   . GLY B 2 204 ? 275.175 292.014 300.001 1.00 125.70 ? 202 GLY B O   1 
ATOM   4892  N  N   . GLU B 2 205 ? 274.205 293.627 298.757 1.00 123.37 ? 203 GLU B N   1 
ATOM   4893  C  CA  . GLU B 2 205 ? 274.745 293.143 297.492 1.00 123.44 ? 203 GLU B CA  1 
ATOM   4894  C  C   . GLU B 2 205 ? 274.131 291.800 297.115 1.00 122.71 ? 203 GLU B C   1 
ATOM   4895  O  O   . GLU B 2 205 ? 273.404 291.197 297.911 1.00 122.84 ? 203 GLU B O   1 
ATOM   4896  C  CB  . GLU B 2 205 ? 276.269 293.030 297.569 1.00 120.20 ? 203 GLU B CB  1 
ATOM   4897  C  CG  . GLU B 2 205 ? 276.966 293.086 296.220 1.00 118.39 ? 203 GLU B CG  1 
ATOM   4898  C  CD  . GLU B 2 205 ? 276.269 294.013 295.244 1.00 121.13 ? 203 GLU B CD  1 
ATOM   4899  O  OE1 . GLU B 2 205 ? 276.587 295.221 295.239 1.00 121.31 ? 203 GLU B OE1 1 
ATOM   4900  O  OE2 . GLU B 2 205 ? 275.404 293.535 294.481 1.00 121.21 ? 203 GLU B OE2 1 
ATOM   4901  N  N   . VAL B 2 206 ? 274.411 291.330 295.904 1.00 119.80 ? 204 VAL B N   1 
ATOM   4902  C  CA  . VAL B 2 206 ? 273.876 290.072 295.415 1.00 115.97 ? 204 VAL B CA  1 
ATOM   4903  C  C   . VAL B 2 206 ? 274.981 289.024 295.424 1.00 109.96 ? 204 VAL B C   1 
ATOM   4904  O  O   . VAL B 2 206 ? 276.175 289.334 295.443 1.00 110.09 ? 204 VAL B O   1 
ATOM   4905  C  CB  . VAL B 2 206 ? 273.265 290.219 294.004 1.00 115.75 ? 204 VAL B CB  1 
ATOM   4906  C  CG1 . VAL B 2 206 ? 272.400 291.467 293.930 1.00 116.12 ? 204 VAL B CG1 1 
ATOM   4907  C  CG2 . VAL B 2 206 ? 274.365 290.259 292.954 1.00 107.88 ? 204 VAL B CG2 1 
ATOM   4908  N  N   . ARG B 2 207 ? 274.574 287.757 295.412 1.00 104.11 ? 205 ARG B N   1 
ATOM   4909  C  CA  . ARG B 2 207 ? 275.518 286.647 295.417 1.00 96.59  ? 205 ARG B CA  1 
ATOM   4910  C  C   . ARG B 2 207 ? 274.933 285.489 294.624 1.00 84.11  ? 205 ARG B C   1 
ATOM   4911  O  O   . ARG B 2 207 ? 273.791 285.087 294.862 1.00 81.93  ? 205 ARG B O   1 
ATOM   4912  C  CB  . ARG B 2 207 ? 275.842 286.207 296.849 1.00 99.96  ? 205 ARG B CB  1 
ATOM   4913  C  CG  . ARG B 2 207 ? 276.925 285.151 296.940 1.00 93.89  ? 205 ARG B CG  1 
ATOM   4914  C  CD  . ARG B 2 207 ? 276.396 283.884 297.579 1.00 91.95  ? 205 ARG B CD  1 
ATOM   4915  N  NE  . ARG B 2 207 ? 275.566 284.167 298.743 1.00 101.72 ? 205 ARG B NE  1 
ATOM   4916  C  CZ  . ARG B 2 207 ? 275.923 283.911 299.994 1.00 107.04 ? 205 ARG B CZ  1 
ATOM   4917  N  NH1 . ARG B 2 207 ? 277.095 283.370 300.281 1.00 104.64 ? 205 ARG B NH1 1 
ATOM   4918  N  NH2 . ARG B 2 207 ? 275.082 284.205 300.981 1.00 108.17 ? 205 ARG B NH2 1 
ATOM   4919  N  N   . ASN B 2 208 ? 275.717 284.960 293.688 1.00 78.30  ? 206 ASN B N   1 
ATOM   4920  C  CA  . ASN B 2 208 ? 275.328 283.815 292.875 1.00 70.41  ? 206 ASN B CA  1 
ATOM   4921  C  C   . ASN B 2 208 ? 276.060 282.577 293.371 1.00 67.61  ? 206 ASN B C   1 
ATOM   4922  O  O   . ASN B 2 208 ? 277.293 282.571 293.451 1.00 72.39  ? 206 ASN B O   1 
ATOM   4923  C  CB  . ASN B 2 208 ? 275.645 284.057 291.398 1.00 69.33  ? 206 ASN B CB  1 
ATOM   4924  C  CG  . ASN B 2 208 ? 274.853 285.207 290.814 1.00 74.03  ? 206 ASN B CG  1 
ATOM   4925  O  OD1 . ASN B 2 208 ? 275.419 286.151 290.265 1.00 73.25  ? 206 ASN B OD1 1 
ATOM   4926  N  ND2 . ASN B 2 208 ? 273.534 285.131 290.925 1.00 74.73  ? 206 ASN B ND2 1 
ATOM   4927  N  N   . GLN B 2 209 ? 275.306 281.534 293.694 1.00 61.67  ? 207 GLN B N   1 
ATOM   4928  C  CA  . GLN B 2 209 ? 275.877 280.302 294.237 1.00 60.84  ? 207 GLN B CA  1 
ATOM   4929  C  C   . GLN B 2 209 ? 275.526 279.115 293.355 1.00 59.51  ? 207 GLN B C   1 
ATOM   4930  O  O   . GLN B 2 209 ? 274.344 278.727 293.288 1.00 54.98  ? 207 GLN B O   1 
ATOM   4931  C  CB  . GLN B 2 209 ? 275.373 280.059 295.659 1.00 64.44  ? 207 GLN B CB  1 
ATOM   4932  C  CG  . GLN B 2 209 ? 274.846 281.295 296.354 1.00 73.84  ? 207 GLN B CG  1 
ATOM   4933  C  CD  . GLN B 2 209 ? 274.478 281.028 297.798 1.00 82.11  ? 207 GLN B CD  1 
ATOM   4934  O  OE1 . GLN B 2 209 ? 274.825 279.987 298.356 1.00 77.96  ? 207 GLN B OE1 1 
ATOM   4935  N  NE2 . GLN B 2 209 ? 273.763 281.964 298.410 1.00 86.56  ? 207 GLN B NE2 1 
ATOM   4936  N  N   . PRO B 2 210 ? 276.487 278.506 292.663 1.00 60.01  ? 208 PRO B N   1 
ATOM   4937  C  CA  . PRO B 2 210 ? 276.206 277.232 291.994 1.00 53.74  ? 208 PRO B CA  1 
ATOM   4938  C  C   . PRO B 2 210 ? 275.807 276.175 293.012 1.00 51.24  ? 208 PRO B C   1 
ATOM   4939  O  O   . PRO B 2 210 ? 276.377 276.090 294.102 1.00 53.99  ? 208 PRO B O   1 
ATOM   4940  C  CB  . PRO B 2 210 ? 277.533 276.890 291.309 1.00 49.22  ? 208 PRO B CB  1 
ATOM   4941  C  CG  . PRO B 2 210 ? 278.230 278.203 291.167 1.00 49.06  ? 208 PRO B CG  1 
ATOM   4942  C  CD  . PRO B 2 210 ? 277.853 278.982 292.388 1.00 54.92  ? 208 PRO B CD  1 
ATOM   4943  N  N   . LEU B 2 211 ? 274.819 275.361 292.647 1.00 48.40  ? 209 LEU B N   1 
ATOM   4944  C  CA  . LEU B 2 211 ? 274.248 274.399 293.585 1.00 52.72  ? 209 LEU B CA  1 
ATOM   4945  C  C   . LEU B 2 211 ? 274.904 273.025 293.466 1.00 48.89  ? 209 LEU B C   1 
ATOM   4946  O  O   . LEU B 2 211 ? 275.486 272.524 294.433 1.00 50.98  ? 209 LEU B O   1 
ATOM   4947  C  CB  . LEU B 2 211 ? 272.733 274.302 293.370 1.00 50.79  ? 209 LEU B CB  1 
ATOM   4948  C  CG  . LEU B 2 211 ? 271.939 275.584 293.634 1.00 48.85  ? 209 LEU B CG  1 
ATOM   4949  C  CD1 . LEU B 2 211 ? 270.469 275.391 293.307 1.00 45.47  ? 209 LEU B CD1 1 
ATOM   4950  C  CD2 . LEU B 2 211 ? 272.115 276.037 295.074 1.00 52.84  ? 209 LEU B CD2 1 
ATOM   4951  N  N   . PHE B 2 212 ? 274.825 272.411 292.291 1.00 47.11  ? 210 PHE B N   1 
ATOM   4952  C  CA  . PHE B 2 212 ? 275.376 271.077 292.084 1.00 45.39  ? 210 PHE B CA  1 
ATOM   4953  C  C   . PHE B 2 212 ? 275.418 270.800 290.588 1.00 47.96  ? 210 PHE B C   1 
ATOM   4954  O  O   . PHE B 2 212 ? 274.870 271.555 289.781 1.00 46.78  ? 210 PHE B O   1 
ATOM   4955  C  CB  . PHE B 2 212 ? 274.558 270.010 292.817 1.00 43.72  ? 210 PHE B CB  1 
ATOM   4956  C  CG  . PHE B 2 212 ? 273.072 270.182 292.680 1.00 47.37  ? 210 PHE B CG  1 
ATOM   4957  C  CD1 . PHE B 2 212 ? 272.436 269.921 291.478 1.00 44.58  ? 210 PHE B CD1 1 
ATOM   4958  C  CD2 . PHE B 2 212 ? 272.310 270.606 293.755 1.00 49.14  ? 210 PHE B CD2 1 
ATOM   4959  C  CE1 . PHE B 2 212 ? 271.071 270.081 291.352 1.00 43.93  ? 210 PHE B CE1 1 
ATOM   4960  C  CE2 . PHE B 2 212 ? 270.945 270.767 293.633 1.00 46.93  ? 210 PHE B CE2 1 
ATOM   4961  C  CZ  . PHE B 2 212 ? 270.325 270.505 292.431 1.00 45.18  ? 210 PHE B CZ  1 
ATOM   4962  N  N   . TRP B 2 213 ? 276.075 269.701 290.231 1.00 44.21  ? 211 TRP B N   1 
ATOM   4963  C  CA  . TRP B 2 213 ? 276.201 269.279 288.843 1.00 42.11  ? 211 TRP B CA  1 
ATOM   4964  C  C   . TRP B 2 213 ? 275.240 268.131 288.570 1.00 41.59  ? 211 TRP B C   1 
ATOM   4965  O  O   . TRP B 2 213 ? 275.150 267.187 289.361 1.00 44.33  ? 211 TRP B O   1 
ATOM   4966  C  CB  . TRP B 2 213 ? 277.635 268.853 288.525 1.00 43.67  ? 211 TRP B CB  1 
ATOM   4967  C  CG  . TRP B 2 213 ? 278.553 270.001 288.245 1.00 40.42  ? 211 TRP B CG  1 
ATOM   4968  C  CD1 . TRP B 2 213 ? 279.520 270.495 289.067 1.00 41.00  ? 211 TRP B CD1 1 
ATOM   4969  C  CD2 . TRP B 2 213 ? 278.582 270.808 287.062 1.00 38.43  ? 211 TRP B CD2 1 
ATOM   4970  N  NE1 . TRP B 2 213 ? 280.155 271.554 288.469 1.00 41.60  ? 211 TRP B NE1 1 
ATOM   4971  C  CE2 . TRP B 2 213 ? 279.596 271.768 287.237 1.00 39.96  ? 211 TRP B CE2 1 
ATOM   4972  C  CE3 . TRP B 2 213 ? 277.851 270.810 285.871 1.00 37.04  ? 211 TRP B CE3 1 
ATOM   4973  C  CZ2 . TRP B 2 213 ? 279.897 272.720 286.267 1.00 36.69  ? 211 TRP B CZ2 1 
ATOM   4974  C  CZ3 . TRP B 2 213 ? 278.150 271.755 284.911 1.00 31.48  ? 211 TRP B CZ3 1 
ATOM   4975  C  CH2 . TRP B 2 213 ? 279.164 272.697 285.113 1.00 32.51  ? 211 TRP B CH2 1 
ATOM   4976  N  N   . ILE B 2 214 ? 274.523 268.220 287.456 1.00 42.37  ? 212 ILE B N   1 
ATOM   4977  C  CA  . ILE B 2 214 ? 273.585 267.180 287.047 1.00 39.31  ? 212 ILE B CA  1 
ATOM   4978  C  C   . ILE B 2 214 ? 274.047 266.607 285.713 1.00 41.72  ? 212 ILE B C   1 
ATOM   4979  O  O   . ILE B 2 214 ? 273.889 267.264 284.674 1.00 41.73  ? 212 ILE B O   1 
ATOM   4980  C  CB  . ILE B 2 214 ? 272.152 267.725 286.945 1.00 37.15  ? 212 ILE B CB  1 
ATOM   4981  C  CG1 . ILE B 2 214 ? 271.741 268.402 288.253 1.00 40.39  ? 212 ILE B CG1 1 
ATOM   4982  C  CG2 . ILE B 2 214 ? 271.181 266.610 286.585 1.00 38.71  ? 212 ILE B CG2 1 
ATOM   4983  C  CD1 . ILE B 2 214 ? 270.728 269.509 288.072 1.00 36.31  ? 212 ILE B CD1 1 
ATOM   4984  N  N   . PRO B 2 215 ? 274.629 265.409 285.687 1.00 43.84  ? 213 PRO B N   1 
ATOM   4985  C  CA  . PRO B 2 215 ? 274.997 264.809 284.400 1.00 39.55  ? 213 PRO B CA  1 
ATOM   4986  C  C   . PRO B 2 215 ? 273.778 264.707 283.497 1.00 38.18  ? 213 PRO B C   1 
ATOM   4987  O  O   . PRO B 2 215 ? 272.700 264.291 283.923 1.00 40.90  ? 213 PRO B O   1 
ATOM   4988  C  CB  . PRO B 2 215 ? 275.535 263.427 284.788 1.00 37.27  ? 213 PRO B CB  1 
ATOM   4989  C  CG  . PRO B 2 215 ? 275.874 263.529 286.236 1.00 41.14  ? 213 PRO B CG  1 
ATOM   4990  C  CD  . PRO B 2 215 ? 274.930 264.526 286.825 1.00 40.51  ? 213 PRO B CD  1 
ATOM   4991  N  N   . TYR B 2 216 ? 273.960 265.091 282.232 1.00 39.41  ? 214 TYR B N   1 
ATOM   4992  C  CA  . TYR B 2 216 ? 272.815 265.190 281.335 1.00 38.52  ? 214 TYR B CA  1 
ATOM   4993  C  C   . TYR B 2 216 ? 272.178 263.832 281.072 1.00 40.94  ? 214 TYR B C   1 
ATOM   4994  O  O   . TYR B 2 216 ? 270.968 263.755 280.840 1.00 45.58  ? 214 TYR B O   1 
ATOM   4995  C  CB  . TYR B 2 216 ? 273.221 265.848 280.018 1.00 33.83  ? 214 TYR B CB  1 
ATOM   4996  C  CG  . TYR B 2 216 ? 272.035 266.320 279.213 1.00 37.25  ? 214 TYR B CG  1 
ATOM   4997  C  CD1 . TYR B 2 216 ? 271.283 267.411 279.627 1.00 39.05  ? 214 TYR B CD1 1 
ATOM   4998  C  CD2 . TYR B 2 216 ? 271.652 265.664 278.052 1.00 36.84  ? 214 TYR B CD2 1 
ATOM   4999  C  CE1 . TYR B 2 216 ? 270.194 267.842 278.902 1.00 36.43  ? 214 TYR B CE1 1 
ATOM   5000  C  CE2 . TYR B 2 216 ? 270.564 266.089 277.321 1.00 37.75  ? 214 TYR B CE2 1 
ATOM   5001  C  CZ  . TYR B 2 216 ? 269.838 267.178 277.750 1.00 38.38  ? 214 TYR B CZ  1 
ATOM   5002  O  OH  . TYR B 2 216 ? 268.751 267.606 277.024 1.00 44.61  ? 214 TYR B OH  1 
ATOM   5003  N  N   . GLU B 2 217 ? 272.966 262.757 281.095 1.00 41.82  ? 215 GLU B N   1 
ATOM   5004  C  CA  . GLU B 2 217 ? 272.395 261.430 280.898 1.00 39.94  ? 215 GLU B CA  1 
ATOM   5005  C  C   . GLU B 2 217 ? 271.414 261.083 282.010 1.00 41.67  ? 215 GLU B C   1 
ATOM   5006  O  O   . GLU B 2 217 ? 270.399 260.419 281.771 1.00 46.49  ? 215 GLU B O   1 
ATOM   5007  C  CB  . GLU B 2 217 ? 273.508 260.386 280.816 1.00 40.62  ? 215 GLU B CB  1 
ATOM   5008  C  CG  . GLU B 2 217 ? 274.353 260.276 282.075 1.00 48.82  ? 215 GLU B CG  1 
ATOM   5009  C  CD  . GLU B 2 217 ? 275.706 260.946 281.933 1.00 55.67  ? 215 GLU B CD  1 
ATOM   5010  O  OE1 . GLU B 2 217 ? 275.747 262.133 281.548 1.00 52.60  ? 215 GLU B OE1 1 
ATOM   5011  O  OE2 . GLU B 2 217 ? 276.729 260.284 282.206 1.00 55.51  ? 215 GLU B OE2 1 
ATOM   5012  N  N   . ASN B 2 218 ? 271.701 261.523 283.237 1.00 41.27  ? 216 ASN B N   1 
ATOM   5013  C  CA  . ASN B 2 218 ? 270.816 261.227 284.358 1.00 40.96  ? 216 ASN B CA  1 
ATOM   5014  C  C   . ASN B 2 218 ? 269.454 261.889 284.186 1.00 48.85  ? 216 ASN B C   1 
ATOM   5015  O  O   . ASN B 2 218 ? 268.420 261.280 284.486 1.00 57.90  ? 216 ASN B O   1 
ATOM   5016  C  CB  . ASN B 2 218 ? 271.467 261.673 285.666 1.00 42.36  ? 216 ASN B CB  1 
ATOM   5017  C  CG  . ASN B 2 218 ? 272.664 260.825 286.041 1.00 45.89  ? 216 ASN B CG  1 
ATOM   5018  O  OD1 . ASN B 2 218 ? 273.179 260.063 285.223 1.00 46.69  ? 216 ASN B OD1 1 
ATOM   5019  N  ND2 . ASN B 2 218 ? 273.117 260.958 287.280 1.00 49.21  ? 216 ASN B ND2 1 
ATOM   5020  N  N   . ILE B 2 219 ? 269.429 263.136 283.708 1.00 46.10  ? 217 ILE B N   1 
ATOM   5021  C  CA  . ILE B 2 219 ? 268.183 263.895 283.628 1.00 43.97  ? 217 ILE B CA  1 
ATOM   5022  C  C   . ILE B 2 219 ? 267.487 263.776 282.279 1.00 46.76  ? 217 ILE B C   1 
ATOM   5023  O  O   . ILE B 2 219 ? 266.315 264.165 282.164 1.00 51.18  ? 217 ILE B O   1 
ATOM   5024  C  CB  . ILE B 2 219 ? 268.434 265.385 283.937 1.00 47.98  ? 217 ILE B CB  1 
ATOM   5025  C  CG1 . ILE B 2 219 ? 267.110 266.126 284.119 1.00 45.45  ? 217 ILE B CG1 1 
ATOM   5026  C  CG2 . ILE B 2 219 ? 269.264 266.027 282.838 1.00 42.06  ? 217 ILE B CG2 1 
ATOM   5027  C  CD1 . ILE B 2 219 ? 266.600 266.120 285.539 1.00 51.39  ? 217 ILE B CD1 1 
ATOM   5028  N  N   . ARG B 2 220 ? 268.160 263.247 281.259 1.00 44.68  ? 218 ARG B N   1 
ATOM   5029  C  CA  . ARG B 2 220 ? 267.573 263.216 279.921 1.00 48.94  ? 218 ARG B CA  1 
ATOM   5030  C  C   . ARG B 2 220 ? 266.232 262.499 279.877 1.00 55.86  ? 218 ARG B C   1 
ATOM   5031  O  O   . ARG B 2 220 ? 265.285 263.043 279.283 1.00 54.60  ? 218 ARG B O   1 
ATOM   5032  C  CB  . ARG B 2 220 ? 268.570 262.586 278.944 1.00 46.71  ? 218 ARG B CB  1 
ATOM   5033  C  CG  . ARG B 2 220 ? 268.181 262.723 277.484 1.00 48.28  ? 218 ARG B CG  1 
ATOM   5034  C  CD  . ARG B 2 220 ? 268.357 261.409 276.746 1.00 57.34  ? 218 ARG B CD  1 
ATOM   5035  N  NE  . ARG B 2 220 ? 267.090 260.712 276.564 1.00 64.96  ? 218 ARG B NE  1 
ATOM   5036  C  CZ  . ARG B 2 220 ? 266.782 259.553 277.131 1.00 62.62  ? 218 ARG B CZ  1 
ATOM   5037  N  NH1 . ARG B 2 220 ? 267.631 258.927 277.929 1.00 57.60  ? 218 ARG B NH1 1 
ATOM   5038  N  NH2 . ARG B 2 220 ? 265.592 259.010 276.892 1.00 55.69  ? 218 ARG B NH2 1 
ATOM   5039  N  N   . PRO B 2 221 ? 266.073 261.304 280.449 1.00 56.08  ? 219 PRO B N   1 
ATOM   5040  C  CA  . PRO B 2 221 ? 264.765 260.633 280.371 1.00 53.48  ? 219 PRO B CA  1 
ATOM   5041  C  C   . PRO B 2 221 ? 263.630 261.433 280.987 1.00 54.49  ? 219 PRO B C   1 
ATOM   5042  O  O   . PRO B 2 221 ? 262.499 261.372 280.489 1.00 54.88  ? 219 PRO B O   1 
ATOM   5043  C  CB  . PRO B 2 221 ? 265.000 259.315 281.125 1.00 52.52  ? 219 PRO B CB  1 
ATOM   5044  C  CG  . PRO B 2 221 ? 266.265 259.521 281.905 1.00 49.29  ? 219 PRO B CG  1 
ATOM   5045  C  CD  . PRO B 2 221 ? 267.090 260.456 281.089 1.00 48.50  ? 219 PRO B CD  1 
ATOM   5046  N  N   . TYR B 2 222 ? 263.895 262.187 282.056 1.00 52.92  ? 220 TYR B N   1 
ATOM   5047  C  CA  . TYR B 2 222 ? 262.826 262.887 282.758 1.00 52.64  ? 220 TYR B CA  1 
ATOM   5048  C  C   . TYR B 2 222 ? 262.369 264.145 282.031 1.00 52.76  ? 220 TYR B C   1 
ATOM   5049  O  O   . TYR B 2 222 ? 261.184 264.491 282.093 1.00 57.79  ? 220 TYR B O   1 
ATOM   5050  C  CB  . TYR B 2 222 ? 263.277 263.240 284.173 1.00 49.32  ? 220 TYR B CB  1 
ATOM   5051  C  CG  . TYR B 2 222 ? 263.587 262.032 285.022 1.00 53.65  ? 220 TYR B CG  1 
ATOM   5052  C  CD1 . TYR B 2 222 ? 262.594 261.122 285.353 1.00 51.51  ? 220 TYR B CD1 1 
ATOM   5053  C  CD2 . TYR B 2 222 ? 264.872 261.798 285.488 1.00 55.77  ? 220 TYR B CD2 1 
ATOM   5054  C  CE1 . TYR B 2 222 ? 262.871 260.017 286.127 1.00 57.48  ? 220 TYR B CE1 1 
ATOM   5055  C  CE2 . TYR B 2 222 ? 265.159 260.695 286.262 1.00 57.23  ? 220 TYR B CE2 1 
ATOM   5056  C  CZ  . TYR B 2 222 ? 264.155 259.807 286.579 1.00 61.31  ? 220 TYR B CZ  1 
ATOM   5057  O  OH  . TYR B 2 222 ? 264.436 258.705 287.351 1.00 64.48  ? 220 TYR B OH  1 
ATOM   5058  N  N   . ILE B 2 223 ? 263.279 264.845 281.346 1.00 49.96  ? 221 ILE B N   1 
ATOM   5059  C  CA  . ILE B 2 223 ? 262.917 266.082 280.664 1.00 48.61  ? 221 ILE B CA  1 
ATOM   5060  C  C   . ILE B 2 223 ? 262.550 265.859 279.206 1.00 50.92  ? 221 ILE B C   1 
ATOM   5061  O  O   . ILE B 2 223 ? 262.276 266.831 278.490 1.00 53.45  ? 221 ILE B O   1 
ATOM   5062  C  CB  . ILE B 2 223 ? 264.049 267.126 280.757 1.00 44.32  ? 221 ILE B CB  1 
ATOM   5063  C  CG1 . ILE B 2 223 ? 265.370 266.537 280.263 1.00 44.90  ? 221 ILE B CG1 1 
ATOM   5064  C  CG2 . ILE B 2 223 ? 264.184 267.633 282.180 1.00 42.71  ? 221 ILE B CG2 1 
ATOM   5065  C  CD1 . ILE B 2 223 ? 266.428 267.579 279.985 1.00 39.82  ? 221 ILE B CD1 1 
ATOM   5066  N  N   . ALA B 2 224 ? 262.538 264.614 278.741 1.00 52.98  ? 222 ALA B N   1 
ATOM   5067  C  CA  . ALA B 2 224 ? 262.106 264.295 277.389 1.00 49.88  ? 222 ALA B CA  1 
ATOM   5068  C  C   . ALA B 2 224 ? 260.606 264.064 277.293 1.00 51.32  ? 222 ALA B C   1 
ATOM   5069  O  O   . ALA B 2 224 ? 260.103 263.793 276.198 1.00 54.78  ? 222 ALA B O   1 
ATOM   5070  C  CB  . ALA B 2 224 ? 262.852 263.062 276.873 1.00 49.52  ? 222 ALA B CB  1 
ATOM   5071  N  N   . ARG B 2 225 ? 259.883 264.159 278.410 1.00 55.42  ? 223 ARG B N   1 
ATOM   5072  C  CA  . ARG B 2 225 ? 258.448 263.924 278.431 1.00 58.30  ? 223 ARG B CA  1 
ATOM   5073  C  C   . ARG B 2 225 ? 257.626 265.169 278.726 1.00 61.57  ? 223 ARG B C   1 
ATOM   5074  O  O   . ARG B 2 225 ? 256.448 265.210 278.357 1.00 64.39  ? 223 ARG B O   1 
ATOM   5075  C  CB  . ARG B 2 225 ? 258.103 262.846 279.469 1.00 62.09  ? 223 ARG B CB  1 
ATOM   5076  C  CG  . ARG B 2 225 ? 258.874 261.548 279.293 1.00 65.68  ? 223 ARG B CG  1 
ATOM   5077  C  CD  . ARG B 2 225 ? 258.371 260.474 280.243 1.00 72.67  ? 223 ARG B CD  1 
ATOM   5078  N  NE  . ARG B 2 225 ? 258.479 260.892 281.635 1.00 75.74  ? 223 ARG B NE  1 
ATOM   5079  C  CZ  . ARG B 2 225 ? 259.396 260.445 282.483 1.00 74.41  ? 223 ARG B CZ  1 
ATOM   5080  N  NH1 . ARG B 2 225 ? 260.307 259.560 282.113 1.00 71.19  ? 223 ARG B NH1 1 
ATOM   5081  N  NH2 . ARG B 2 225 ? 259.399 260.897 283.734 1.00 70.93  ? 223 ARG B NH2 1 
ATOM   5082  N  N   . GLU B 2 226 ? 258.207 266.177 279.370 1.00 61.69  ? 224 GLU B N   1 
ATOM   5083  C  CA  . GLU B 2 226 ? 257.485 267.390 279.724 1.00 62.99  ? 224 GLU B CA  1 
ATOM   5084  C  C   . GLU B 2 226 ? 257.497 268.365 278.554 1.00 57.79  ? 224 GLU B C   1 
ATOM   5085  O  O   . GLU B 2 226 ? 258.561 268.690 278.018 1.00 53.44  ? 224 GLU B O   1 
ATOM   5086  C  CB  . GLU B 2 226 ? 258.101 268.040 280.963 1.00 67.55  ? 224 GLU B CB  1 
ATOM   5087  C  CG  . GLU B 2 226 ? 257.779 267.327 282.270 1.00 71.54  ? 224 GLU B CG  1 
ATOM   5088  C  CD  . GLU B 2 226 ? 256.295 267.059 282.449 1.00 75.06  ? 224 GLU B CD  1 
ATOM   5089  O  OE1 . GLU B 2 226 ? 255.481 267.693 281.745 1.00 71.09  ? 224 GLU B OE1 1 
ATOM   5090  O  OE2 . GLU B 2 226 ? 255.942 266.214 283.298 1.00 77.79  ? 224 GLU B OE2 1 
ATOM   5091  N  N   . ARG B 2 227 ? 256.313 268.828 278.164 1.00 55.15  ? 225 ARG B N   1 
ATOM   5092  C  CA  . ARG B 2 227 ? 256.172 269.774 277.068 1.00 47.86  ? 225 ARG B CA  1 
ATOM   5093  C  C   . ARG B 2 227 ? 256.202 271.203 277.590 1.00 45.70  ? 225 ARG B C   1 
ATOM   5094  O  O   . ARG B 2 227 ? 255.667 271.498 278.662 1.00 54.46  ? 225 ARG B O   1 
ATOM   5095  C  CB  . ARG B 2 227 ? 254.870 269.529 276.304 1.00 49.30  ? 225 ARG B CB  1 
ATOM   5096  C  CG  . ARG B 2 227 ? 254.420 268.086 276.298 1.00 52.24  ? 225 ARG B CG  1 
ATOM   5097  C  CD  . ARG B 2 227 ? 255.241 267.271 275.321 1.00 52.39  ? 225 ARG B CD  1 
ATOM   5098  N  NE  . ARG B 2 227 ? 255.258 267.875 273.994 1.00 59.03  ? 225 ARG B NE  1 
ATOM   5099  C  CZ  . ARG B 2 227 ? 255.762 267.294 272.915 1.00 65.36  ? 225 ARG B CZ  1 
ATOM   5100  N  NH1 . ARG B 2 227 ? 256.304 266.088 272.968 1.00 61.13  ? 225 ARG B NH1 1 
ATOM   5101  N  NH2 . ARG B 2 227 ? 255.724 267.940 271.753 1.00 57.89  ? 225 ARG B NH2 1 
ATOM   5102  N  N   . VAL B 2 228 ? 256.827 272.089 276.819 1.00 44.57  ? 226 VAL B N   1 
ATOM   5103  C  CA  . VAL B 2 228 ? 256.962 273.496 277.168 1.00 41.75  ? 226 VAL B CA  1 
ATOM   5104  C  C   . VAL B 2 228 ? 256.718 274.329 275.916 1.00 39.96  ? 226 VAL B C   1 
ATOM   5105  O  O   . VAL B 2 228 ? 256.654 273.812 274.800 1.00 42.24  ? 226 VAL B O   1 
ATOM   5106  C  CB  . VAL B 2 228 ? 258.346 273.816 277.770 1.00 41.96  ? 226 VAL B CB  1 
ATOM   5107  C  CG1 . VAL B 2 228 ? 258.679 272.835 278.878 1.00 40.56  ? 226 VAL B CG1 1 
ATOM   5108  C  CG2 . VAL B 2 228 ? 259.414 273.784 276.688 1.00 36.97  ? 226 VAL B CG2 1 
ATOM   5109  N  N   . MET B 2 229 ? 256.575 275.634 276.115 1.00 38.44  ? 227 MET B N   1 
ATOM   5110  C  CA  . MET B 2 229 ? 256.439 276.580 275.016 1.00 38.19  ? 227 MET B CA  1 
ATOM   5111  C  C   . MET B 2 229 ? 257.752 277.333 274.845 1.00 37.19  ? 227 MET B C   1 
ATOM   5112  O  O   . MET B 2 229 ? 258.345 277.789 275.828 1.00 39.40  ? 227 MET B O   1 
ATOM   5113  C  CB  . MET B 2 229 ? 255.279 277.548 275.263 1.00 38.33  ? 227 MET B CB  1 
ATOM   5114  C  CG  . MET B 2 229 ? 255.649 278.829 275.986 1.00 38.55  ? 227 MET B CG  1 
ATOM   5115  S  SD  . MET B 2 229 ? 254.267 279.507 276.922 1.00 52.38  ? 227 MET B SD  1 
ATOM   5116  C  CE  . MET B 2 229 ? 255.084 280.791 277.863 1.00 39.70  ? 227 MET B CE  1 
ATOM   5117  N  N   . LEU B 2 230 ? 258.206 277.448 273.601 1.00 38.97  ? 228 LEU B N   1 
ATOM   5118  C  CA  . LEU B 2 230 ? 259.515 278.010 273.298 1.00 37.08  ? 228 LEU B CA  1 
ATOM   5119  C  C   . LEU B 2 230 ? 259.488 279.510 273.048 1.00 38.17  ? 228 LEU B C   1 
ATOM   5120  O  O   . LEU B 2 230 ? 260.542 280.093 272.778 1.00 42.40  ? 228 LEU B O   1 
ATOM   5121  C  CB  . LEU B 2 230 ? 260.117 277.307 272.078 1.00 38.82  ? 228 LEU B CB  1 
ATOM   5122  C  CG  . LEU B 2 230 ? 260.386 275.809 272.216 1.00 40.28  ? 228 LEU B CG  1 
ATOM   5123  C  CD1 . LEU B 2 230 ? 260.726 275.206 270.864 1.00 33.79  ? 228 LEU B CD1 1 
ATOM   5124  C  CD2 . LEU B 2 230 ? 261.497 275.556 273.220 1.00 35.30  ? 228 LEU B CD2 1 
ATOM   5125  N  N   . SER B 2 231 ? 258.326 280.150 273.133 1.00 40.42  ? 229 SER B N   1 
ATOM   5126  C  CA  . SER B 2 231 ? 258.227 281.565 272.815 1.00 36.52  ? 229 SER B CA  1 
ATOM   5127  C  C   . SER B 2 231 ? 257.129 282.198 273.654 1.00 36.64  ? 229 SER B C   1 
ATOM   5128  O  O   . SER B 2 231 ? 256.234 281.517 274.160 1.00 37.79  ? 229 SER B O   1 
ATOM   5129  C  CB  . SER B 2 231 ? 257.949 281.784 271.323 1.00 38.10  ? 229 SER B CB  1 
ATOM   5130  O  OG  . SER B 2 231 ? 258.234 283.116 270.933 1.00 43.71  ? 229 SER B OG  1 
ATOM   5131  N  N   . SER B 2 232 ? 257.217 283.518 273.803 1.00 37.49  ? 230 SER B N   1 
ATOM   5132  C  CA  . SER B 2 232 ? 256.133 284.292 274.388 1.00 38.00  ? 230 SER B CA  1 
ATOM   5133  C  C   . SER B 2 232 ? 255.092 284.709 273.361 1.00 37.43  ? 230 SER B C   1 
ATOM   5134  O  O   . SER B 2 232 ? 253.992 285.120 273.744 1.00 36.84  ? 230 SER B O   1 
ATOM   5135  C  CB  . SER B 2 232 ? 256.685 285.540 275.082 1.00 36.27  ? 230 SER B CB  1 
ATOM   5136  O  OG  . SER B 2 232 ? 257.349 285.201 276.285 1.00 45.99  ? 230 SER B OG  1 
ATOM   5137  N  N   . LEU B 2 233 ? 255.416 284.614 272.073 1.00 37.93  ? 231 LEU B N   1 
ATOM   5138  C  CA  . LEU B 2 233 ? 254.487 284.946 271.003 1.00 36.41  ? 231 LEU B CA  1 
ATOM   5139  C  C   . LEU B 2 233 ? 253.691 283.744 270.515 1.00 36.70  ? 231 LEU B C   1 
ATOM   5140  O  O   . LEU B 2 233 ? 252.786 283.913 269.692 1.00 38.53  ? 231 LEU B O   1 
ATOM   5141  C  CB  . LEU B 2 233 ? 255.243 285.572 269.828 1.00 34.79  ? 231 LEU B CB  1 
ATOM   5142  C  CG  . LEU B 2 233 ? 255.905 286.916 270.128 1.00 39.59  ? 231 LEU B CG  1 
ATOM   5143  C  CD1 . LEU B 2 233 ? 256.532 287.500 268.876 1.00 49.35  ? 231 LEU B CD1 1 
ATOM   5144  C  CD2 . LEU B 2 233 ? 254.899 287.882 270.725 1.00 36.92  ? 231 LEU B CD2 1 
ATOM   5145  N  N   . ASN B 2 234 ? 254.008 282.545 270.996 1.00 33.85  ? 232 ASN B N   1 
ATOM   5146  C  CA  . ASN B 2 234 ? 253.254 281.342 270.657 1.00 31.94  ? 232 ASN B CA  1 
ATOM   5147  C  C   . ASN B 2 234 ? 253.303 280.435 271.877 1.00 32.99  ? 232 ASN B C   1 
ATOM   5148  O  O   . ASN B 2 234 ? 254.360 279.885 272.198 1.00 38.23  ? 232 ASN B O   1 
ATOM   5149  C  CB  . ASN B 2 234 ? 253.830 280.647 269.424 1.00 33.34  ? 232 ASN B CB  1 
ATOM   5150  C  CG  . ASN B 2 234 ? 253.002 279.452 268.988 1.00 31.81  ? 232 ASN B CG  1 
ATOM   5151  O  OD1 . ASN B 2 234 ? 252.161 278.959 269.737 1.00 35.02  ? 232 ASN B OD1 1 
ATOM   5152  N  ND2 . ASN B 2 234 ? 253.238 278.980 267.771 1.00 31.12  ? 232 ASN B ND2 1 
ATOM   5153  N  N   . ASN B 2 235 ? 252.168 280.285 272.552 1.00 34.85  ? 233 ASN B N   1 
ATOM   5154  C  CA  . ASN B 2 235 ? 252.100 279.569 273.816 1.00 33.47  ? 233 ASN B CA  1 
ATOM   5155  C  C   . ASN B 2 235 ? 251.807 278.085 273.645 1.00 33.95  ? 233 ASN B C   1 
ATOM   5156  O  O   . ASN B 2 235 ? 251.500 277.410 274.631 1.00 41.31  ? 233 ASN B O   1 
ATOM   5157  C  CB  . ASN B 2 235 ? 251.045 280.207 274.723 1.00 32.47  ? 233 ASN B CB  1 
ATOM   5158  C  CG  . ASN B 2 235 ? 251.232 281.702 274.867 1.00 31.04  ? 233 ASN B CG  1 
ATOM   5159  O  OD1 . ASN B 2 235 ? 250.268 282.463 274.847 1.00 31.63  ? 233 ASN B OD1 1 
ATOM   5160  N  ND2 . ASN B 2 235 ? 252.479 282.130 275.016 1.00 32.81  ? 233 ASN B ND2 1 
ATOM   5161  N  N   . THR B 2 236 ? 251.878 277.567 272.423 1.00 36.23  ? 234 THR B N   1 
ATOM   5162  C  CA  . THR B 2 236 ? 251.729 276.134 272.217 1.00 38.92  ? 234 THR B CA  1 
ATOM   5163  C  C   . THR B 2 236 ? 252.897 275.393 272.855 1.00 40.18  ? 234 THR B C   1 
ATOM   5164  O  O   . THR B 2 236 ? 254.056 275.783 272.695 1.00 42.38  ? 234 THR B O   1 
ATOM   5165  C  CB  . THR B 2 236 ? 251.652 275.818 270.724 1.00 37.25  ? 234 THR B CB  1 
ATOM   5166  O  OG1 . THR B 2 236 ? 250.750 276.730 270.089 1.00 38.33  ? 234 THR B OG1 1 
ATOM   5167  C  CG2 . THR B 2 236 ? 251.161 274.399 270.504 1.00 39.35  ? 234 THR B CG2 1 
ATOM   5168  N  N   . ARG B 2 237 ? 252.587 274.325 273.584 1.00 41.01  ? 235 ARG B N   1 
ATOM   5169  C  CA  . ARG B 2 237 ? 253.609 273.516 274.245 1.00 40.75  ? 235 ARG B CA  1 
ATOM   5170  C  C   . ARG B 2 237 ? 253.965 272.325 273.358 1.00 41.11  ? 235 ARG B C   1 
ATOM   5171  O  O   . ARG B 2 237 ? 253.668 271.167 273.653 1.00 46.37  ? 235 ARG B O   1 
ATOM   5172  C  CB  . ARG B 2 237 ? 253.125 273.072 275.622 1.00 38.08  ? 235 ARG B CB  1 
ATOM   5173  C  CG  . ARG B 2 237 ? 253.040 274.194 276.639 1.00 44.40  ? 235 ARG B CG  1 
ATOM   5174  C  CD  . ARG B 2 237 ? 252.220 273.777 277.846 1.00 51.95  ? 235 ARG B CD  1 
ATOM   5175  N  NE  . ARG B 2 237 ? 252.817 272.648 278.547 1.00 52.85  ? 235 ARG B NE  1 
ATOM   5176  C  CZ  . ARG B 2 237 ? 252.253 272.018 279.569 1.00 59.46  ? 235 ARG B CZ  1 
ATOM   5177  N  NH1 . ARG B 2 237 ? 251.069 272.380 280.035 1.00 60.48  ? 235 ARG B NH1 1 
ATOM   5178  N  NH2 . ARG B 2 237 ? 252.892 270.999 280.135 1.00 53.78  ? 235 ARG B NH2 1 
ATOM   5179  N  N   . ASN B 2 238 ? 254.619 272.641 272.243 1.00 44.75  ? 236 ASN B N   1 
ATOM   5180  C  CA  . ASN B 2 238 ? 254.926 271.662 271.210 1.00 51.87  ? 236 ASN B CA  1 
ATOM   5181  C  C   . ASN B 2 238 ? 256.338 271.099 271.311 1.00 56.02  ? 236 ASN B C   1 
ATOM   5182  O  O   . ASN B 2 238 ? 256.740 270.323 270.439 1.00 60.23  ? 236 ASN B O   1 
ATOM   5183  C  CB  . ASN B 2 238 ? 254.722 272.274 269.817 1.00 50.08  ? 236 ASN B CB  1 
ATOM   5184  C  CG  . ASN B 2 238 ? 255.314 273.670 269.688 1.00 52.96  ? 236 ASN B CG  1 
ATOM   5185  O  OD1 . ASN B 2 238 ? 255.797 274.254 270.658 1.00 47.34  ? 236 ASN B OD1 1 
ATOM   5186  N  ND2 . ASN B 2 238 ? 255.278 274.211 268.476 1.00 56.23  ? 236 ASN B ND2 1 
ATOM   5187  N  N   . SER B 2 239 ? 257.098 271.462 272.340 1.00 51.93  ? 237 SER B N   1 
ATOM   5188  C  CA  . SER B 2 239 ? 258.479 271.020 272.478 1.00 46.59  ? 237 SER B CA  1 
ATOM   5189  C  C   . SER B 2 239 ? 258.728 270.561 273.909 1.00 42.78  ? 237 SER B C   1 
ATOM   5190  O  O   . SER B 2 239 ? 257.854 270.641 274.775 1.00 44.29  ? 237 SER B O   1 
ATOM   5191  C  CB  . SER B 2 239 ? 259.457 272.134 272.086 1.00 49.21  ? 237 SER B CB  1 
ATOM   5192  O  OG  . SER B 2 239 ? 259.826 272.029 270.722 1.00 56.94  ? 237 SER B OG  1 
ATOM   5193  N  N   . THR B 2 240 ? 259.940 270.069 274.150 1.00 43.05  ? 238 THR B N   1 
ATOM   5194  C  CA  . THR B 2 240 ? 260.367 269.609 275.462 1.00 43.15  ? 238 THR B CA  1 
ATOM   5195  C  C   . THR B 2 240 ? 261.714 270.235 275.800 1.00 42.21  ? 238 THR B C   1 
ATOM   5196  O  O   . THR B 2 240 ? 262.404 270.783 274.937 1.00 44.02  ? 238 THR B O   1 
ATOM   5197  C  CB  . THR B 2 240 ? 260.459 268.077 275.520 1.00 44.17  ? 238 THR B CB  1 
ATOM   5198  O  OG1 . THR B 2 240 ? 261.640 267.640 274.838 1.00 47.31  ? 238 THR B OG1 1 
ATOM   5199  C  CG2 . THR B 2 240 ? 259.246 267.446 274.863 1.00 46.73  ? 238 THR B CG2 1 
ATOM   5200  N  N   . ILE B 2 241 ? 262.082 270.158 277.080 1.00 40.63  ? 239 ILE B N   1 
ATOM   5201  C  CA  . ILE B 2 241 ? 263.371 270.691 277.514 1.00 39.68  ? 239 ILE B CA  1 
ATOM   5202  C  C   . ILE B 2 241 ? 264.510 269.947 276.829 1.00 39.77  ? 239 ILE B C   1 
ATOM   5203  O  O   . ILE B 2 241 ? 265.546 270.535 276.494 1.00 41.56  ? 239 ILE B O   1 
ATOM   5204  C  CB  . ILE B 2 241 ? 263.491 270.622 279.047 1.00 37.68  ? 239 ILE B CB  1 
ATOM   5205  C  CG1 . ILE B 2 241 ? 262.347 271.397 279.703 1.00 40.35  ? 239 ILE B CG1 1 
ATOM   5206  C  CG2 . ILE B 2 241 ? 264.842 271.149 279.502 1.00 36.95  ? 239 ILE B CG2 1 
ATOM   5207  C  CD1 . ILE B 2 241 ? 262.513 272.897 279.640 1.00 39.48  ? 239 ILE B CD1 1 
ATOM   5208  N  N   . ASP B 2 242 ? 264.339 268.642 276.616 1.00 40.31  ? 240 ASP B N   1 
ATOM   5209  C  CA  . ASP B 2 242 ? 265.344 267.875 275.890 1.00 41.33  ? 240 ASP B CA  1 
ATOM   5210  C  C   . ASP B 2 242 ? 265.517 268.407 274.474 1.00 41.87  ? 240 ASP B C   1 
ATOM   5211  O  O   . ASP B 2 242 ? 266.644 268.520 273.980 1.00 43.87  ? 240 ASP B O   1 
ATOM   5212  C  CB  . ASP B 2 242 ? 264.961 266.397 275.872 1.00 46.59  ? 240 ASP B CB  1 
ATOM   5213  C  CG  . ASP B 2 242 ? 266.065 265.517 275.330 1.00 54.90  ? 240 ASP B CG  1 
ATOM   5214  O  OD1 . ASP B 2 242 ? 267.232 265.717 275.724 1.00 50.94  ? 240 ASP B OD1 1 
ATOM   5215  O  OD2 . ASP B 2 242 ? 265.766 264.621 274.514 1.00 62.86  ? 240 ASP B OD2 1 
ATOM   5216  N  N   . ASP B 2 243 ? 264.412 268.734 273.801 1.00 42.22  ? 241 ASP B N   1 
ATOM   5217  C  CA  . ASP B 2 243 ? 264.511 269.361 272.487 1.00 40.78  ? 241 ASP B CA  1 
ATOM   5218  C  C   . ASP B 2 243 ? 265.181 270.724 272.582 1.00 39.20  ? 241 ASP B C   1 
ATOM   5219  O  O   . ASP B 2 243 ? 265.949 271.112 271.696 1.00 41.38  ? 241 ASP B O   1 
ATOM   5220  C  CB  . ASP B 2 243 ? 263.125 269.491 271.856 1.00 43.92  ? 241 ASP B CB  1 
ATOM   5221  C  CG  . ASP B 2 243 ? 262.502 268.149 271.535 1.00 49.30  ? 241 ASP B CG  1 
ATOM   5222  O  OD1 . ASP B 2 243 ? 263.231 267.251 271.065 1.00 48.40  ? 241 ASP B OD1 1 
ATOM   5223  O  OD2 . ASP B 2 243 ? 261.282 267.993 271.748 1.00 53.83  ? 241 ASP B OD2 1 
ATOM   5224  N  N   . PHE B 2 244 ? 264.894 271.468 273.651 1.00 37.16  ? 242 PHE B N   1 
ATOM   5225  C  CA  . PHE B 2 244 ? 265.502 272.782 273.826 1.00 37.59  ? 242 PHE B CA  1 
ATOM   5226  C  C   . PHE B 2 244 ? 267.019 272.680 273.920 1.00 36.64  ? 242 PHE B C   1 
ATOM   5227  O  O   . PHE B 2 244 ? 267.741 273.476 273.310 1.00 35.94  ? 242 PHE B O   1 
ATOM   5228  C  CB  . PHE B 2 244 ? 264.922 273.452 275.072 1.00 38.23  ? 242 PHE B CB  1 
ATOM   5229  C  CG  . PHE B 2 244 ? 265.537 274.782 275.393 1.00 36.13  ? 242 PHE B CG  1 
ATOM   5230  C  CD1 . PHE B 2 244 ? 265.177 275.915 274.687 1.00 35.24  ? 242 PHE B CD1 1 
ATOM   5231  C  CD2 . PHE B 2 244 ? 266.469 274.900 276.409 1.00 32.11  ? 242 PHE B CD2 1 
ATOM   5232  C  CE1 . PHE B 2 244 ? 265.736 277.137 274.984 1.00 33.15  ? 242 PHE B CE1 1 
ATOM   5233  C  CE2 . PHE B 2 244 ? 267.032 276.119 276.709 1.00 34.76  ? 242 PHE B CE2 1 
ATOM   5234  C  CZ  . PHE B 2 244 ? 266.665 277.239 275.997 1.00 36.33  ? 242 PHE B CZ  1 
ATOM   5235  N  N   . PHE B 2 245 ? 267.522 271.704 274.679 1.00 36.07  ? 243 PHE B N   1 
ATOM   5236  C  CA  . PHE B 2 245 ? 268.966 271.538 274.812 1.00 35.29  ? 243 PHE B CA  1 
ATOM   5237  C  C   . PHE B 2 245 ? 269.594 270.920 273.566 1.00 36.24  ? 243 PHE B C   1 
ATOM   5238  O  O   . PHE B 2 245 ? 270.675 271.340 273.142 1.00 36.31  ? 243 PHE B O   1 
ATOM   5239  C  CB  . PHE B 2 245 ? 269.288 270.691 276.042 1.00 30.43  ? 243 PHE B CB  1 
ATOM   5240  C  CG  . PHE B 2 245 ? 269.330 271.472 277.320 1.00 32.36  ? 243 PHE B CG  1 
ATOM   5241  C  CD1 . PHE B 2 245 ? 270.194 272.543 277.462 1.00 35.81  ? 243 PHE B CD1 1 
ATOM   5242  C  CD2 . PHE B 2 245 ? 268.508 271.135 278.380 1.00 31.82  ? 243 PHE B CD2 1 
ATOM   5243  C  CE1 . PHE B 2 245 ? 270.237 273.263 278.636 1.00 33.34  ? 243 PHE B CE1 1 
ATOM   5244  C  CE2 . PHE B 2 245 ? 268.547 271.851 279.557 1.00 30.17  ? 243 PHE B CE2 1 
ATOM   5245  C  CZ  . PHE B 2 245 ? 269.412 272.916 279.685 1.00 31.28  ? 243 PHE B CZ  1 
ATOM   5246  N  N   . ARG B 2 246 ? 268.936 269.923 272.969 1.00 35.50  ? 244 ARG B N   1 
ATOM   5247  C  CA  . ARG B 2 246 ? 269.515 269.228 271.825 1.00 33.07  ? 244 ARG B CA  1 
ATOM   5248  C  C   . ARG B 2 246 ? 269.610 270.128 270.602 1.00 38.26  ? 244 ARG B C   1 
ATOM   5249  O  O   . ARG B 2 246 ? 270.547 269.994 269.807 1.00 39.13  ? 244 ARG B O   1 
ATOM   5250  C  CB  . ARG B 2 246 ? 268.694 267.981 271.500 1.00 33.18  ? 244 ARG B CB  1 
ATOM   5251  C  CG  . ARG B 2 246 ? 269.221 267.174 270.324 1.00 33.23  ? 244 ARG B CG  1 
ATOM   5252  C  CD  . ARG B 2 246 ? 270.431 266.344 270.718 1.00 31.50  ? 244 ARG B CD  1 
ATOM   5253  N  NE  . ARG B 2 246 ? 270.884 265.486 269.631 1.00 34.39  ? 244 ARG B NE  1 
ATOM   5254  C  CZ  . ARG B 2 246 ? 271.779 265.838 268.719 1.00 34.31  ? 244 ARG B CZ  1 
ATOM   5255  N  NH1 . ARG B 2 246 ? 272.345 267.033 268.731 1.00 35.13  ? 244 ARG B NH1 1 
ATOM   5256  N  NH2 . ARG B 2 246 ? 272.116 264.969 267.771 1.00 34.66  ? 244 ARG B NH2 1 
ATOM   5257  N  N   . LEU B 2 247 ? 268.656 271.039 270.428 1.00 37.40  ? 245 LEU B N   1 
ATOM   5258  C  CA  . LEU B 2 247 ? 268.686 271.969 269.309 1.00 37.76  ? 245 LEU B CA  1 
ATOM   5259  C  C   . LEU B 2 247 ? 269.555 273.187 269.582 1.00 36.07  ? 245 LEU B C   1 
ATOM   5260  O  O   . LEU B 2 247 ? 269.700 274.034 268.695 1.00 41.89  ? 245 LEU B O   1 
ATOM   5261  C  CB  . LEU B 2 247 ? 267.265 272.416 268.957 1.00 38.70  ? 245 LEU B CB  1 
ATOM   5262  C  CG  . LEU B 2 247 ? 266.351 271.346 268.358 1.00 42.01  ? 245 LEU B CG  1 
ATOM   5263  C  CD1 . LEU B 2 247 ? 264.960 271.902 268.112 1.00 38.70  ? 245 LEU B CD1 1 
ATOM   5264  C  CD2 . LEU B 2 247 ? 266.943 270.794 267.073 1.00 43.50  ? 245 LEU B CD2 1 
ATOM   5265  N  N   . ASN B 2 248 ? 270.134 273.291 270.777 1.00 35.63  ? 246 ASN B N   1 
ATOM   5266  C  CA  . ASN B 2 248 ? 270.992 274.417 271.141 1.00 34.34  ? 246 ASN B CA  1 
ATOM   5267  C  C   . ASN B 2 248 ? 270.259 275.745 270.962 1.00 37.13  ? 246 ASN B C   1 
ATOM   5268  O  O   . ASN B 2 248 ? 270.736 276.662 270.290 1.00 39.75  ? 246 ASN B O   1 
ATOM   5269  C  CB  . ASN B 2 248 ? 272.295 274.392 270.339 1.00 39.90  ? 246 ASN B CB  1 
ATOM   5270  C  CG  . ASN B 2 248 ? 273.220 273.273 270.769 1.00 47.76  ? 246 ASN B CG  1 
ATOM   5271  O  OD1 . ASN B 2 248 ? 273.824 273.331 271.839 1.00 48.96  ? 246 ASN B OD1 1 
ATOM   5272  N  ND2 . ASN B 2 248 ? 273.334 272.245 269.936 1.00 46.17  ? 246 ASN B ND2 1 
ATOM   5273  N  N   . LEU B 2 249 ? 269.082 275.841 271.574 1.00 37.77  ? 247 LEU B N   1 
ATOM   5274  C  CA  . LEU B 2 249 ? 268.291 277.061 271.532 1.00 35.39  ? 247 LEU B CA  1 
ATOM   5275  C  C   . LEU B 2 249 ? 268.642 278.034 272.647 1.00 38.52  ? 247 LEU B C   1 
ATOM   5276  O  O   . LEU B 2 249 ? 268.150 279.167 272.637 1.00 41.22  ? 247 LEU B O   1 
ATOM   5277  C  CB  . LEU B 2 249 ? 266.798 276.726 271.598 1.00 36.82  ? 247 LEU B CB  1 
ATOM   5278  C  CG  . LEU B 2 249 ? 266.262 275.884 270.440 1.00 37.85  ? 247 LEU B CG  1 
ATOM   5279  C  CD1 . LEU B 2 249 ? 264.785 275.582 270.631 1.00 35.77  ? 247 LEU B CD1 1 
ATOM   5280  C  CD2 . LEU B 2 249 ? 266.505 276.584 269.114 1.00 36.72  ? 247 LEU B CD2 1 
ATOM   5281  N  N   . TYR B 2 250 ? 269.469 277.623 273.602 1.00 41.46  ? 248 TYR B N   1 
ATOM   5282  C  CA  . TYR B 2 250 ? 269.892 278.510 274.671 1.00 40.43  ? 248 TYR B CA  1 
ATOM   5283  C  C   . TYR B 2 250 ? 271.024 279.413 274.199 1.00 43.46  ? 248 TYR B C   1 
ATOM   5284  O  O   . TYR B 2 250 ? 271.825 279.044 273.336 1.00 40.83  ? 248 TYR B O   1 
ATOM   5285  C  CB  . TYR B 2 250 ? 270.338 277.707 275.892 1.00 37.71  ? 248 TYR B CB  1 
ATOM   5286  C  CG  . TYR B 2 250 ? 271.410 276.685 275.597 1.00 41.58  ? 248 TYR B CG  1 
ATOM   5287  C  CD1 . TYR B 2 250 ? 271.087 275.454 275.044 1.00 37.03  ? 248 TYR B CD1 1 
ATOM   5288  C  CD2 . TYR B 2 250 ? 272.744 276.950 275.872 1.00 40.02  ? 248 TYR B CD2 1 
ATOM   5289  C  CE1 . TYR B 2 250 ? 272.061 274.518 274.775 1.00 35.43  ? 248 TYR B CE1 1 
ATOM   5290  C  CE2 . TYR B 2 250 ? 273.723 276.020 275.605 1.00 36.38  ? 248 TYR B CE2 1 
ATOM   5291  C  CZ  . TYR B 2 250 ? 273.377 274.806 275.056 1.00 37.03  ? 248 TYR B CZ  1 
ATOM   5292  O  OH  . TYR B 2 250 ? 274.349 273.873 274.788 1.00 40.14  ? 248 TYR B OH  1 
ATOM   5293  N  N   . LYS B 2 251 ? 271.081 280.611 274.775 1.00 45.78  ? 249 LYS B N   1 
ATOM   5294  C  CA  . LYS B 2 251 ? 272.097 281.604 274.445 1.00 38.47  ? 249 LYS B CA  1 
ATOM   5295  C  C   . LYS B 2 251 ? 272.846 281.978 275.716 1.00 39.20  ? 249 LYS B C   1 
ATOM   5296  O  O   . LYS B 2 251 ? 272.325 282.722 276.555 1.00 46.63  ? 249 LYS B O   1 
ATOM   5297  C  CB  . LYS B 2 251 ? 271.471 282.837 273.795 1.00 42.05  ? 249 LYS B CB  1 
ATOM   5298  C  CG  . LYS B 2 251 ? 270.764 282.554 272.480 1.00 46.97  ? 249 LYS B CG  1 
ATOM   5299  C  CD  . LYS B 2 251 ? 271.756 282.503 271.330 1.00 51.21  ? 249 LYS B CD  1 
ATOM   5300  C  CE  . LYS B 2 251 ? 271.259 281.607 270.209 1.00 55.02  ? 249 LYS B CE  1 
ATOM   5301  N  NZ  . LYS B 2 251 ? 270.733 280.313 270.724 1.00 50.67  ? 249 LYS B NZ  1 
ATOM   5302  N  N   . GLY B 2 252 ? 274.070 281.461 275.857 1.00 39.19  ? 250 GLY B N   1 
ATOM   5303  C  CA  . GLY B 2 252 ? 274.921 281.812 276.969 1.00 38.07  ? 250 GLY B CA  1 
ATOM   5304  C  C   . GLY B 2 252 ? 276.295 282.236 276.481 1.00 41.69  ? 250 GLY B C   1 
ATOM   5305  O  O   . GLY B 2 252 ? 276.673 281.995 275.332 1.00 45.36  ? 250 GLY B O   1 
ATOM   5306  N  N   . ASP B 2 253 ? 277.035 282.879 277.376 1.00 39.67  ? 251 ASP B N   1 
ATOM   5307  C  CA  . ASP B 2 253 ? 278.397 283.300 277.090 1.00 39.11  ? 251 ASP B CA  1 
ATOM   5308  C  C   . ASP B 2 253 ? 279.395 282.319 277.698 1.00 36.45  ? 251 ASP B C   1 
ATOM   5309  O  O   . ASP B 2 253 ? 279.143 281.709 278.740 1.00 36.78  ? 251 ASP B O   1 
ATOM   5310  C  CB  . ASP B 2 253 ? 278.643 284.740 277.576 1.00 41.63  ? 251 ASP B CB  1 
ATOM   5311  C  CG  . ASP B 2 253 ? 278.928 284.843 279.076 1.00 54.08  ? 251 ASP B CG  1 
ATOM   5312  O  OD1 . ASP B 2 253 ? 279.145 285.982 279.549 1.00 64.80  ? 251 ASP B OD1 1 
ATOM   5313  O  OD2 . ASP B 2 253 ? 278.896 283.829 279.796 1.00 50.45  ? 251 ASP B OD2 1 
ATOM   5314  N  N   . ILE B 2 254 ? 280.518 282.139 277.005 1.00 35.43  ? 252 ILE B N   1 
ATOM   5315  C  CA  . ILE B 2 254 ? 281.543 281.214 277.471 1.00 32.90  ? 252 ILE B CA  1 
ATOM   5316  C  C   . ILE B 2 254 ? 282.162 281.772 278.743 1.00 32.64  ? 252 ILE B C   1 
ATOM   5317  O  O   . ILE B 2 254 ? 282.749 282.860 278.742 1.00 39.38  ? 252 ILE B O   1 
ATOM   5318  C  CB  . ILE B 2 254 ? 282.604 280.977 276.390 1.00 33.28  ? 252 ILE B CB  1 
ATOM   5319  C  CG1 . ILE B 2 254 ? 282.027 280.129 275.256 1.00 34.62  ? 252 ILE B CG1 1 
ATOM   5320  C  CG2 . ILE B 2 254 ? 283.824 280.290 276.981 1.00 29.94  ? 252 ILE B CG2 1 
ATOM   5321  C  CD1 . ILE B 2 254 ? 282.251 280.707 273.881 1.00 33.09  ? 252 ILE B CD1 1 
ATOM   5322  N  N   . VAL B 2 255 ? 282.032 281.028 279.838 1.00 31.44  ? 253 VAL B N   1 
ATOM   5323  C  CA  . VAL B 2 255 ? 282.678 281.399 281.087 1.00 31.83  ? 253 VAL B CA  1 
ATOM   5324  C  C   . VAL B 2 255 ? 283.934 280.576 281.339 1.00 32.90  ? 253 VAL B C   1 
ATOM   5325  O  O   . VAL B 2 255 ? 284.788 281.000 282.132 1.00 39.52  ? 253 VAL B O   1 
ATOM   5326  C  CB  . VAL B 2 255 ? 281.708 281.266 282.280 1.00 33.56  ? 253 VAL B CB  1 
ATOM   5327  C  CG1 . VAL B 2 255 ? 280.475 282.127 282.060 1.00 33.62  ? 253 VAL B CG1 1 
ATOM   5328  C  CG2 . VAL B 2 255 ? 281.323 279.814 282.490 1.00 28.61  ? 253 VAL B CG2 1 
ATOM   5329  N  N   . LYS B 2 256 ? 284.074 279.419 280.697 1.00 34.44  ? 254 LYS B N   1 
ATOM   5330  C  CA  . LYS B 2 256 ? 285.271 278.612 280.880 1.00 30.28  ? 254 LYS B CA  1 
ATOM   5331  C  C   . LYS B 2 256 ? 285.518 277.763 279.643 1.00 31.43  ? 254 LYS B C   1 
ATOM   5332  O  O   . LYS B 2 256 ? 284.605 277.469 278.871 1.00 33.11  ? 254 LYS B O   1 
ATOM   5333  C  CB  . LYS B 2 256 ? 285.159 277.721 282.121 1.00 30.18  ? 254 LYS B CB  1 
ATOM   5334  C  CG  . LYS B 2 256 ? 286.418 276.939 282.439 1.00 30.96  ? 254 LYS B CG  1 
ATOM   5335  C  CD  . LYS B 2 256 ? 286.306 276.244 283.780 1.00 34.77  ? 254 LYS B CD  1 
ATOM   5336  C  CE  . LYS B 2 256 ? 287.315 275.119 283.903 1.00 37.32  ? 254 LYS B CE  1 
ATOM   5337  N  NZ  . LYS B 2 256 ? 288.516 275.364 283.063 1.00 39.04  ? 254 LYS B NZ  1 
ATOM   5338  N  N   . THR B 2 257 ? 286.773 277.362 279.474 1.00 34.55  ? 255 THR B N   1 
ATOM   5339  C  CA  . THR B 2 257 ? 287.175 276.461 278.407 1.00 31.68  ? 255 THR B CA  1 
ATOM   5340  C  C   . THR B 2 257 ? 288.194 275.480 278.963 1.00 31.61  ? 255 THR B C   1 
ATOM   5341  O  O   . THR B 2 257 ? 288.922 275.794 279.906 1.00 39.78  ? 255 THR B O   1 
ATOM   5342  C  CB  . THR B 2 257 ? 287.756 277.232 277.210 1.00 34.65  ? 255 THR B CB  1 
ATOM   5343  O  OG1 . THR B 2 257 ? 286.701 277.594 276.312 1.00 34.36  ? 255 THR B OG1 1 
ATOM   5344  C  CG2 . THR B 2 257 ? 288.788 276.402 276.468 1.00 39.39  ? 255 THR B CG2 1 
ATOM   5345  N  N   . GLU B 2 258 ? 288.226 274.281 278.391 1.00 31.31  ? 256 GLU B N   1 
ATOM   5346  C  CA  . GLU B 2 258 ? 289.224 273.295 278.783 1.00 36.20  ? 256 GLU B CA  1 
ATOM   5347  C  C   . GLU B 2 258 ? 290.569 273.679 278.178 1.00 39.71  ? 256 GLU B C   1 
ATOM   5348  O  O   . GLU B 2 258 ? 290.730 273.678 276.954 1.00 44.14  ? 256 GLU B O   1 
ATOM   5349  C  CB  . GLU B 2 258 ? 288.811 271.895 278.338 1.00 34.09  ? 256 GLU B CB  1 
ATOM   5350  C  CG  . GLU B 2 258 ? 289.262 270.802 279.290 1.00 41.57  ? 256 GLU B CG  1 
ATOM   5351  C  CD  . GLU B 2 258 ? 289.224 269.424 278.668 1.00 46.77  ? 256 GLU B CD  1 
ATOM   5352  O  OE1 . GLU B 2 258 ? 290.162 269.085 277.920 1.00 51.99  ? 256 GLU B OE1 1 
ATOM   5353  O  OE2 . GLU B 2 258 ? 288.261 268.676 278.933 1.00 52.79  ? 256 GLU B OE2 1 
ATOM   5354  N  N   . ASN B 2 259 ? 291.531 274.011 279.035 1.00 39.31  ? 257 ASN B N   1 
ATOM   5355  C  CA  . ASN B 2 259 ? 292.857 274.408 278.591 1.00 36.87  ? 257 ASN B CA  1 
ATOM   5356  C  C   . ASN B 2 259 ? 293.893 273.750 279.488 1.00 39.45  ? 257 ASN B C   1 
ATOM   5357  O  O   . ASN B 2 259 ? 293.578 273.245 280.568 1.00 42.77  ? 257 ASN B O   1 
ATOM   5358  C  CB  . ASN B 2 259 ? 293.031 275.935 278.591 1.00 35.44  ? 257 ASN B CB  1 
ATOM   5359  C  CG  . ASN B 2 259 ? 292.622 276.572 279.902 1.00 39.58  ? 257 ASN B CG  1 
ATOM   5360  O  OD1 . ASN B 2 259 ? 293.446 276.770 280.793 1.00 46.97  ? 257 ASN B OD1 1 
ATOM   5361  N  ND2 . ASN B 2 259 ? 291.345 276.905 280.024 1.00 38.17  ? 257 ASN B ND2 1 
ATOM   5362  N  N   . LEU B 2 260 ? 295.142 273.757 279.021 1.00 40.31  ? 258 LEU B N   1 
ATOM   5363  C  CA  . LEU B 2 260 ? 296.203 273.042 279.718 1.00 40.53  ? 258 LEU B CA  1 
ATOM   5364  C  C   . LEU B 2 260 ? 296.490 273.617 281.098 1.00 41.10  ? 258 LEU B C   1 
ATOM   5365  O  O   . LEU B 2 260 ? 297.036 272.907 281.950 1.00 40.78  ? 258 LEU B O   1 
ATOM   5366  C  CB  . LEU B 2 260 ? 297.479 273.051 278.874 1.00 32.01  ? 258 LEU B CB  1 
ATOM   5367  C  CG  . LEU B 2 260 ? 297.396 272.303 277.542 1.00 31.68  ? 258 LEU B CG  1 
ATOM   5368  C  CD1 . LEU B 2 260 ? 298.516 272.727 276.606 1.00 38.18  ? 258 LEU B CD1 1 
ATOM   5369  C  CD2 . LEU B 2 260 ? 297.425 270.804 277.770 1.00 32.42  ? 258 LEU B CD2 1 
ATOM   5370  N  N   . HIS B 2 261 ? 296.136 274.875 281.341 1.00 41.48  ? 259 HIS B N   1 
ATOM   5371  C  CA  . HIS B 2 261 ? 296.386 275.514 282.625 1.00 42.99  ? 259 HIS B CA  1 
ATOM   5372  C  C   . HIS B 2 261 ? 295.198 275.442 283.574 1.00 46.02  ? 259 HIS B C   1 
ATOM   5373  O  O   . HIS B 2 261 ? 295.312 275.903 284.714 1.00 51.19  ? 259 HIS B O   1 
ATOM   5374  C  CB  . HIS B 2 261 ? 296.780 276.977 282.416 1.00 44.53  ? 259 HIS B CB  1 
ATOM   5375  C  CG  . HIS B 2 261 ? 298.120 277.154 281.776 1.00 51.30  ? 259 HIS B CG  1 
ATOM   5376  N  ND1 . HIS B 2 261 ? 298.274 277.648 280.499 1.00 55.98  ? 259 HIS B ND1 1 
ATOM   5377  C  CD2 . HIS B 2 261 ? 299.368 276.901 282.235 1.00 50.93  ? 259 HIS B CD2 1 
ATOM   5378  C  CE1 . HIS B 2 261 ? 299.560 277.693 280.199 1.00 57.38  ? 259 HIS B CE1 1 
ATOM   5379  N  NE2 . HIS B 2 261 ? 300.245 277.245 281.236 1.00 57.68  ? 259 HIS B NE2 1 
ATOM   5380  N  N   . ASN B 2 262 ? 294.073 274.876 283.143 1.00 42.59  ? 260 ASN B N   1 
ATOM   5381  C  CA  . ASN B 2 262 ? 292.855 274.845 283.950 1.00 42.73  ? 260 ASN B CA  1 
ATOM   5382  C  C   . ASN B 2 262 ? 292.456 276.255 284.380 1.00 47.34  ? 260 ASN B C   1 
ATOM   5383  O  O   . ASN B 2 262 ? 292.257 276.544 285.561 1.00 52.41  ? 260 ASN B O   1 
ATOM   5384  C  CB  . ASN B 2 262 ? 293.025 273.931 285.162 1.00 44.96  ? 260 ASN B CB  1 
ATOM   5385  C  CG  . ASN B 2 262 ? 291.720 273.301 285.603 1.00 51.27  ? 260 ASN B CG  1 
ATOM   5386  O  OD1 . ASN B 2 262 ? 290.741 273.289 284.859 1.00 55.54  ? 260 ASN B OD1 1 
ATOM   5387  N  ND2 . ASN B 2 262 ? 291.699 272.776 286.821 1.00 51.22  ? 260 ASN B ND2 1 
ATOM   5388  N  N   . ARG B 2 263 ? 292.343 277.141 283.397 1.00 49.02  ? 261 ARG B N   1 
ATOM   5389  C  CA  . ARG B 2 263 ? 292.032 278.542 283.636 1.00 48.91  ? 261 ARG B CA  1 
ATOM   5390  C  C   . ARG B 2 263 ? 290.580 278.834 283.286 1.00 49.97  ? 261 ARG B C   1 
ATOM   5391  O  O   . ARG B 2 263 ? 290.090 278.429 282.228 1.00 48.38  ? 261 ARG B O   1 
ATOM   5392  C  CB  . ARG B 2 263 ? 292.941 279.455 282.813 1.00 50.10  ? 261 ARG B CB  1 
ATOM   5393  C  CG  . ARG B 2 263 ? 294.154 279.982 283.549 1.00 57.35  ? 261 ARG B CG  1 
ATOM   5394  C  CD  . ARG B 2 263 ? 294.672 281.239 282.871 1.00 63.74  ? 261 ARG B CD  1 
ATOM   5395  N  NE  . ARG B 2 263 ? 294.474 281.200 281.427 1.00 65.17  ? 261 ARG B NE  1 
ATOM   5396  C  CZ  . ARG B 2 263 ? 294.854 282.160 280.594 1.00 65.66  ? 261 ARG B CZ  1 
ATOM   5397  N  NH1 . ARG B 2 263 ? 295.447 283.259 281.029 1.00 57.71  ? 261 ARG B NH1 1 
ATOM   5398  N  NH2 . ARG B 2 263 ? 294.627 282.016 279.291 1.00 64.57  ? 261 ARG B NH2 1 
ATOM   5399  N  N   . ALA B 2 264 ? 289.898 279.537 284.181 1.00 49.38  ? 262 ALA B N   1 
ATOM   5400  C  CA  . ALA B 2 264 ? 288.594 280.110 283.893 1.00 44.75  ? 262 ALA B CA  1 
ATOM   5401  C  C   . ALA B 2 264 ? 288.771 281.549 283.425 1.00 47.90  ? 262 ALA B C   1 
ATOM   5402  O  O   . ALA B 2 264 ? 289.758 282.210 283.755 1.00 53.30  ? 262 ALA B O   1 
ATOM   5403  C  CB  . ALA B 2 264 ? 287.685 280.060 285.121 1.00 41.36  ? 262 ALA B CB  1 
ATOM   5404  N  N   . LEU B 2 265 ? 287.804 282.029 282.641 1.00 46.35  ? 263 LEU B N   1 
ATOM   5405  C  CA  . LEU B 2 265 ? 287.894 283.388 282.118 1.00 46.05  ? 263 LEU B CA  1 
ATOM   5406  C  C   . LEU B 2 265 ? 287.974 284.417 283.237 1.00 49.91  ? 263 LEU B C   1 
ATOM   5407  O  O   . LEU B 2 265 ? 288.595 285.472 283.067 1.00 51.79  ? 263 LEU B O   1 
ATOM   5408  C  CB  . LEU B 2 265 ? 286.699 283.683 281.213 1.00 45.97  ? 263 LEU B CB  1 
ATOM   5409  C  CG  . LEU B 2 265 ? 286.923 283.524 279.709 1.00 42.74  ? 263 LEU B CG  1 
ATOM   5410  C  CD1 . LEU B 2 265 ? 287.194 282.072 279.354 1.00 39.24  ? 263 LEU B CD1 1 
ATOM   5411  C  CD2 . LEU B 2 265 ? 285.728 284.055 278.937 1.00 43.21  ? 263 LEU B CD2 1 
ATOM   5412  N  N   . ALA B 2 266 ? 287.356 284.134 284.385 1.00 53.53  ? 264 ALA B N   1 
ATOM   5413  C  CA  . ALA B 2 266 ? 287.344 285.086 285.488 1.00 54.39  ? 264 ALA B CA  1 
ATOM   5414  C  C   . ALA B 2 266 ? 288.723 285.322 286.088 1.00 57.68  ? 264 ALA B C   1 
ATOM   5415  O  O   . ALA B 2 266 ? 288.894 286.292 286.833 1.00 64.14  ? 264 ALA B O   1 
ATOM   5416  C  CB  . ALA B 2 266 ? 286.385 284.610 286.579 1.00 52.63  ? 264 ALA B CB  1 
ATOM   5417  N  N   . GLU B 2 267 ? 289.704 284.471 285.792 1.00 56.99  ? 265 GLU B N   1 
ATOM   5418  C  CA  . GLU B 2 267 ? 291.038 284.624 286.355 1.00 55.08  ? 265 GLU B CA  1 
ATOM   5419  C  C   . GLU B 2 267 ? 291.955 285.495 285.508 1.00 56.71  ? 265 GLU B C   1 
ATOM   5420  O  O   . GLU B 2 267 ? 293.053 285.831 285.964 1.00 61.64  ? 265 GLU B O   1 
ATOM   5421  C  CB  . GLU B 2 267 ? 291.684 283.251 286.562 1.00 58.91  ? 265 GLU B CB  1 
ATOM   5422  C  CG  . GLU B 2 267 ? 290.738 282.210 287.132 1.00 58.01  ? 265 GLU B CG  1 
ATOM   5423  C  CD  . GLU B 2 267 ? 291.378 280.844 287.250 1.00 63.29  ? 265 GLU B CD  1 
ATOM   5424  O  OE1 . GLU B 2 267 ? 292.614 280.780 287.416 1.00 68.10  ? 265 GLU B OE1 1 
ATOM   5425  O  OE2 . GLU B 2 267 ? 290.646 279.835 287.182 1.00 58.69  ? 265 GLU B OE2 1 
ATOM   5426  N  N   . TYR B 2 268 ? 291.541 285.870 284.296 1.00 57.63  ? 266 TYR B N   1 
ATOM   5427  C  CA  . TYR B 2 268 ? 292.332 286.790 283.489 1.00 56.64  ? 266 TYR B CA  1 
ATOM   5428  C  C   . TYR B 2 268 ? 291.480 287.823 282.760 1.00 61.99  ? 266 TYR B C   1 
ATOM   5429  O  O   . TYR B 2 268 ? 292.013 288.558 281.919 1.00 64.48  ? 266 TYR B O   1 
ATOM   5430  C  CB  . TYR B 2 268 ? 293.207 286.025 282.487 1.00 56.74  ? 266 TYR B CB  1 
ATOM   5431  C  CG  . TYR B 2 268 ? 292.452 285.161 281.504 1.00 57.06  ? 266 TYR B CG  1 
ATOM   5432  C  CD1 . TYR B 2 268 ? 291.991 283.904 281.868 1.00 56.21  ? 266 TYR B CD1 1 
ATOM   5433  C  CD2 . TYR B 2 268 ? 292.216 285.595 280.209 1.00 58.37  ? 266 TYR B CD2 1 
ATOM   5434  C  CE1 . TYR B 2 268 ? 291.310 283.109 280.972 1.00 53.59  ? 266 TYR B CE1 1 
ATOM   5435  C  CE2 . TYR B 2 268 ? 291.534 284.807 279.307 1.00 53.27  ? 266 TYR B CE2 1 
ATOM   5436  C  CZ  . TYR B 2 268 ? 291.084 283.565 279.693 1.00 53.78  ? 266 TYR B CZ  1 
ATOM   5437  O  OH  . TYR B 2 268 ? 290.404 282.777 278.795 1.00 54.50  ? 266 TYR B OH  1 
ATOM   5438  N  N   . CYS B 2 269 ? 290.184 287.904 283.049 1.00 66.88  ? 267 CYS B N   1 
ATOM   5439  C  CA  . CYS B 2 269 ? 289.319 288.970 282.542 1.00 67.89  ? 267 CYS B CA  1 
ATOM   5440  C  C   . CYS B 2 269 ? 288.731 289.709 283.735 1.00 71.13  ? 267 CYS B C   1 
ATOM   5441  O  O   . CYS B 2 269 ? 287.785 289.212 284.372 1.00 69.27  ? 267 CYS B O   1 
ATOM   5442  C  CB  . CYS B 2 269 ? 288.214 288.408 281.650 1.00 65.91  ? 267 CYS B CB  1 
ATOM   5443  S  SG  . CYS B 2 269 ? 288.773 287.165 280.464 1.00 61.93  ? 267 CYS B SG  1 
ATOM   5444  N  N   . PRO B 2 270 ? 289.252 290.890 284.083 1.00 76.05  ? 268 PRO B N   1 
ATOM   5445  C  CA  . PRO B 2 270 ? 288.848 291.528 285.345 1.00 71.85  ? 268 PRO B CA  1 
ATOM   5446  C  C   . PRO B 2 270 ? 287.478 292.183 285.322 1.00 72.64  ? 268 PRO B C   1 
ATOM   5447  O  O   . PRO B 2 270 ? 286.895 292.376 286.397 1.00 74.62  ? 268 PRO B O   1 
ATOM   5448  C  CB  . PRO B 2 270 ? 289.947 292.575 285.569 1.00 66.48  ? 268 PRO B CB  1 
ATOM   5449  C  CG  . PRO B 2 270 ? 290.395 292.924 284.192 1.00 69.73  ? 268 PRO B CG  1 
ATOM   5450  C  CD  . PRO B 2 270 ? 290.299 291.656 283.384 1.00 72.11  ? 268 PRO B CD  1 
ATOM   5451  N  N   . THR B 2 271 ? 286.943 292.527 284.159 1.00 73.32  ? 269 THR B N   1 
ATOM   5452  C  CA  . THR B 2 271 ? 285.697 293.268 284.066 1.00 73.57  ? 269 THR B CA  1 
ATOM   5453  C  C   . THR B 2 271 ? 284.696 292.542 283.177 1.00 72.88  ? 269 THR B C   1 
ATOM   5454  O  O   . THR B 2 271 ? 285.080 291.739 282.318 1.00 75.46  ? 269 THR B O   1 
ATOM   5455  C  CB  . THR B 2 271 ? 285.941 294.681 283.516 1.00 70.96  ? 269 THR B CB  1 
ATOM   5456  O  OG1 . THR B 2 271 ? 286.167 294.614 282.104 1.00 74.18  ? 269 THR B OG1 1 
ATOM   5457  C  CG2 . THR B 2 271 ? 287.153 295.306 284.184 1.00 63.02  ? 269 THR B CG2 1 
ATOM   5458  N  N   . PRO B 2 272 ? 283.398 292.799 283.362 1.00 69.99  ? 270 PRO B N   1 
ATOM   5459  C  CA  . PRO B 2 272 ? 282.396 292.116 282.525 1.00 71.03  ? 270 PRO B CA  1 
ATOM   5460  C  C   . PRO B 2 272 ? 282.586 292.363 281.040 1.00 71.16  ? 270 PRO B C   1 
ATOM   5461  O  O   . PRO B 2 272 ? 282.351 291.459 280.228 1.00 71.25  ? 270 PRO B O   1 
ATOM   5462  C  CB  . PRO B 2 272 ? 281.066 292.692 283.032 1.00 72.40  ? 270 PRO B CB  1 
ATOM   5463  C  CG  . PRO B 2 272 ? 281.364 293.229 284.394 1.00 71.40  ? 270 PRO B CG  1 
ATOM   5464  C  CD  . PRO B 2 272 ? 282.784 293.695 284.355 1.00 68.54  ? 270 PRO B CD  1 
ATOM   5465  N  N   . ASP B 2 273 ? 283.005 293.572 280.659 1.00 72.16  ? 271 ASP B N   1 
ATOM   5466  C  CA  . ASP B 2 273 ? 283.228 293.862 279.247 1.00 73.65  ? 271 ASP B CA  1 
ATOM   5467  C  C   . ASP B 2 273 ? 284.323 292.973 278.673 1.00 67.74  ? 271 ASP B C   1 
ATOM   5468  O  O   . ASP B 2 273 ? 284.187 292.437 277.566 1.00 64.98  ? 271 ASP B O   1 
ATOM   5469  C  CB  . ASP B 2 273 ? 283.584 295.338 279.069 1.00 72.98  ? 271 ASP B CB  1 
ATOM   5470  C  CG  . ASP B 2 273 ? 283.120 295.893 277.740 1.00 75.96  ? 271 ASP B CG  1 
ATOM   5471  O  OD1 . ASP B 2 273 ? 283.827 295.691 276.730 1.00 79.96  ? 271 ASP B OD1 1 
ATOM   5472  O  OD2 . ASP B 2 273 ? 282.048 296.532 277.705 1.00 73.93  ? 271 ASP B OD2 1 
ATOM   5473  N  N   . SER B 2 274 ? 285.411 292.791 279.421 1.00 65.56  ? 272 SER B N   1 
ATOM   5474  C  CA  . SER B 2 274 ? 286.491 291.932 278.954 1.00 65.79  ? 272 SER B CA  1 
ATOM   5475  C  C   . SER B 2 274 ? 286.056 290.474 278.902 1.00 64.54  ? 272 SER B C   1 
ATOM   5476  O  O   . SER B 2 274 ? 286.465 289.733 278.002 1.00 64.40  ? 272 SER B O   1 
ATOM   5477  C  CB  . SER B 2 274 ? 287.718 292.102 279.848 1.00 70.08  ? 272 SER B CB  1 
ATOM   5478  O  OG  . SER B 2 274 ? 288.507 293.193 279.409 1.00 74.48  ? 272 SER B OG  1 
ATOM   5479  N  N   . MET B 2 275 ? 285.233 290.038 279.859 1.00 64.03  ? 273 MET B N   1 
ATOM   5480  C  CA  . MET B 2 275 ? 284.721 288.673 279.813 1.00 59.03  ? 273 MET B CA  1 
ATOM   5481  C  C   . MET B 2 275 ? 283.863 288.452 278.574 1.00 58.52  ? 273 MET B C   1 
ATOM   5482  O  O   . MET B 2 275 ? 283.971 287.413 277.910 1.00 58.98  ? 273 MET B O   1 
ATOM   5483  C  CB  . MET B 2 275 ? 283.924 288.363 281.079 1.00 53.22  ? 273 MET B CB  1 
ATOM   5484  C  CG  . MET B 2 275 ? 284.729 288.465 282.359 1.00 60.41  ? 273 MET B CG  1 
ATOM   5485  S  SD  . MET B 2 275 ? 285.156 286.853 283.039 1.00 69.74  ? 273 MET B SD  1 
ATOM   5486  C  CE  . MET B 2 275 ? 283.552 286.060 283.064 1.00 52.18  ? 273 MET B CE  1 
ATOM   5487  N  N   . LYS B 2 276 ? 283.008 289.422 278.243 1.00 58.94  ? 274 LYS B N   1 
ATOM   5488  C  CA  . LYS B 2 276 ? 282.210 289.315 277.026 1.00 58.10  ? 274 LYS B CA  1 
ATOM   5489  C  C   . LYS B 2 276 ? 283.098 289.298 275.788 1.00 55.38  ? 274 LYS B C   1 
ATOM   5490  O  O   . LYS B 2 276 ? 282.843 288.545 274.840 1.00 55.88  ? 274 LYS B O   1 
ATOM   5491  C  CB  . LYS B 2 276 ? 281.206 290.464 276.954 1.00 60.65  ? 274 LYS B CB  1 
ATOM   5492  C  CG  . LYS B 2 276 ? 279.941 290.228 277.762 1.00 68.73  ? 274 LYS B CG  1 
ATOM   5493  C  CD  . LYS B 2 276 ? 279.285 291.539 278.157 1.00 79.05  ? 274 LYS B CD  1 
ATOM   5494  C  CE  . LYS B 2 276 ? 278.629 291.438 279.524 1.00 79.05  ? 274 LYS B CE  1 
ATOM   5495  N  NZ  . LYS B 2 276 ? 277.529 290.436 279.540 1.00 76.55  ? 274 LYS B NZ  1 
ATOM   5496  N  N   . MET B 2 277 ? 284.144 290.128 275.774 1.00 55.80  ? 275 MET B N   1 
ATOM   5497  C  CA  . MET B 2 277 ? 285.065 290.134 274.642 1.00 57.71  ? 275 MET B CA  1 
ATOM   5498  C  C   . MET B 2 277 ? 285.746 288.780 274.475 1.00 53.21  ? 275 MET B C   1 
ATOM   5499  O  O   . MET B 2 277 ? 285.876 288.271 273.354 1.00 51.49  ? 275 MET B O   1 
ATOM   5500  C  CB  . MET B 2 277 ? 286.105 291.240 274.825 1.00 59.58  ? 275 MET B CB  1 
ATOM   5501  C  CG  . MET B 2 277 ? 285.714 292.579 274.219 1.00 67.22  ? 275 MET B CG  1 
ATOM   5502  S  SD  . MET B 2 277 ? 284.761 292.423 272.696 1.00 88.03  ? 275 MET B SD  1 
ATOM   5503  C  CE  . MET B 2 277 ? 283.091 292.372 273.338 1.00 63.79  ? 275 MET B CE  1 
ATOM   5504  N  N   . GLU B 2 278 ? 286.189 288.181 275.582 1.00 50.92  ? 276 GLU B N   1 
ATOM   5505  C  CA  . GLU B 2 278 ? 286.839 286.876 275.515 1.00 49.80  ? 276 GLU B CA  1 
ATOM   5506  C  C   . GLU B 2 278 ? 285.868 285.800 275.045 1.00 51.51  ? 276 GLU B C   1 
ATOM   5507  O  O   . GLU B 2 278 ? 286.238 284.915 274.261 1.00 52.77  ? 276 GLU B O   1 
ATOM   5508  C  CB  . GLU B 2 278 ? 287.427 286.512 276.877 1.00 47.65  ? 276 GLU B CB  1 
ATOM   5509  C  CG  . GLU B 2 278 ? 288.107 285.155 276.916 1.00 52.30  ? 276 GLU B CG  1 
ATOM   5510  C  CD  . GLU B 2 278 ? 289.453 285.157 276.221 1.00 57.33  ? 276 GLU B CD  1 
ATOM   5511  O  OE1 . GLU B 2 278 ? 289.634 285.951 275.275 1.00 54.53  ? 276 GLU B OE1 1 
ATOM   5512  O  OE2 . GLU B 2 278 ? 290.331 284.365 276.620 1.00 56.19  ? 276 GLU B OE2 1 
ATOM   5513  N  N   . SER B 2 279 ? 284.624 285.851 275.524 1.00 46.35  ? 277 SER B N   1 
ATOM   5514  C  CA  . SER B 2 279 ? 283.622 284.899 275.059 1.00 41.10  ? 277 SER B CA  1 
ATOM   5515  C  C   . SER B 2 279 ? 283.391 285.039 273.559 1.00 44.04  ? 277 SER B C   1 
ATOM   5516  O  O   . SER B 2 279 ? 283.285 284.037 272.840 1.00 45.04  ? 277 SER B O   1 
ATOM   5517  C  CB  . SER B 2 279 ? 282.318 285.094 275.831 1.00 41.14  ? 277 SER B CB  1 
ATOM   5518  O  OG  . SER B 2 279 ? 281.282 284.290 275.298 1.00 42.53  ? 277 SER B OG  1 
ATOM   5519  N  N   . LYS B 2 280 ? 283.318 286.278 273.068 1.00 43.59  ? 278 LYS B N   1 
ATOM   5520  C  CA  . LYS B 2 280 ? 283.165 286.496 271.634 1.00 47.22  ? 278 LYS B CA  1 
ATOM   5521  C  C   . LYS B 2 280 ? 284.353 285.932 270.864 1.00 49.16  ? 278 LYS B C   1 
ATOM   5522  O  O   . LYS B 2 280 ? 284.183 285.314 269.807 1.00 47.81  ? 278 LYS B O   1 
ATOM   5523  C  CB  . LYS B 2 280 ? 282.996 287.988 271.350 1.00 50.94  ? 278 LYS B CB  1 
ATOM   5524  C  CG  . LYS B 2 280 ? 282.157 288.301 270.126 1.00 55.75  ? 278 LYS B CG  1 
ATOM   5525  C  CD  . LYS B 2 280 ? 281.773 289.771 270.080 1.00 64.81  ? 278 LYS B CD  1 
ATOM   5526  C  CE  . LYS B 2 280 ? 281.334 290.274 271.448 1.00 62.43  ? 278 LYS B CE  1 
ATOM   5527  N  NZ  . LYS B 2 280 ? 279.937 289.876 271.772 1.00 55.56  ? 278 LYS B NZ  1 
ATOM   5528  N  N   . ARG B 2 281 ? 285.566 286.131 271.384 1.00 47.13  ? 279 ARG B N   1 
ATOM   5529  C  CA  . ARG B 2 281 ? 286.758 285.610 270.717 1.00 41.53  ? 279 ARG B CA  1 
ATOM   5530  C  C   . ARG B 2 281 ? 286.738 284.085 270.642 1.00 44.50  ? 279 ARG B C   1 
ATOM   5531  O  O   . ARG B 2 281 ? 287.075 283.499 269.604 1.00 43.31  ? 279 ARG B O   1 
ATOM   5532  C  CB  . ARG B 2 281 ? 288.009 286.104 271.443 1.00 43.41  ? 279 ARG B CB  1 
ATOM   5533  C  CG  . ARG B 2 281 ? 289.266 286.103 270.596 1.00 45.83  ? 279 ARG B CG  1 
ATOM   5534  C  CD  . ARG B 2 281 ? 290.512 286.138 271.460 1.00 43.66  ? 279 ARG B CD  1 
ATOM   5535  N  NE  . ARG B 2 281 ? 290.463 285.150 272.530 1.00 48.92  ? 279 ARG B NE  1 
ATOM   5536  C  CZ  . ARG B 2 281 ? 290.860 283.891 272.406 1.00 51.21  ? 279 ARG B CZ  1 
ATOM   5537  N  NH1 . ARG B 2 281 ? 291.336 283.426 271.263 1.00 50.25  ? 279 ARG B NH1 1 
ATOM   5538  N  NH2 . ARG B 2 281 ? 290.775 283.078 273.454 1.00 49.38  ? 279 ARG B NH2 1 
ATOM   5539  N  N   . ILE B 2 282 ? 286.346 283.422 271.730 1.00 45.73  ? 280 ILE B N   1 
ATOM   5540  C  CA  . ILE B 2 282 ? 286.321 281.961 271.727 1.00 41.72  ? 280 ILE B CA  1 
ATOM   5541  C  C   . ILE B 2 282 ? 285.232 281.442 270.791 1.00 39.56  ? 280 ILE B C   1 
ATOM   5542  O  O   . ILE B 2 282 ? 285.422 280.444 270.078 1.00 42.74  ? 280 ILE B O   1 
ATOM   5543  C  CB  . ILE B 2 282 ? 286.152 281.430 273.161 1.00 41.34  ? 280 ILE B CB  1 
ATOM   5544  C  CG1 . ILE B 2 282 ? 287.330 281.882 274.027 1.00 38.20  ? 280 ILE B CG1 1 
ATOM   5545  C  CG2 . ILE B 2 282 ? 286.051 279.916 273.160 1.00 38.17  ? 280 ILE B CG2 1 
ATOM   5546  C  CD1 . ILE B 2 282 ? 287.055 281.851 275.510 1.00 38.01  ? 280 ILE B CD1 1 
ATOM   5547  N  N   . ASP B 2 283 ? 284.074 282.107 270.774 1.00 38.59  ? 281 ASP B N   1 
ATOM   5548  C  CA  . ASP B 2 283 ? 283.028 281.727 269.832 1.00 37.23  ? 281 ASP B CA  1 
ATOM   5549  C  C   . ASP B 2 283 ? 283.503 281.896 268.396 1.00 39.28  ? 281 ASP B C   1 
ATOM   5550  O  O   . ASP B 2 283 ? 283.178 281.082 267.522 1.00 40.23  ? 281 ASP B O   1 
ATOM   5551  C  CB  . ASP B 2 283 ? 281.770 282.555 270.088 1.00 45.83  ? 281 ASP B CB  1 
ATOM   5552  C  CG  . ASP B 2 283 ? 280.779 281.843 270.981 1.00 47.45  ? 281 ASP B CG  1 
ATOM   5553  O  OD1 . ASP B 2 283 ? 280.497 280.654 270.728 1.00 45.60  ? 281 ASP B OD1 1 
ATOM   5554  O  OD2 . ASP B 2 283 ? 280.287 282.471 271.941 1.00 50.07  ? 281 ASP B OD2 1 
ATOM   5555  N  N   . LYS B 2 284 ? 284.276 282.953 268.135 1.00 43.58  ? 282 LYS B N   1 
ATOM   5556  C  CA  . LYS B 2 284 ? 284.854 283.136 266.811 1.00 42.55  ? 282 LYS B CA  1 
ATOM   5557  C  C   . LYS B 2 284 ? 285.825 282.014 266.475 1.00 41.18  ? 282 LYS B C   1 
ATOM   5558  O  O   . LYS B 2 284 ? 285.881 281.563 265.330 1.00 40.52  ? 282 LYS B O   1 
ATOM   5559  C  CB  . LYS B 2 284 ? 285.550 284.493 266.719 1.00 42.82  ? 282 LYS B CB  1 
ATOM   5560  C  CG  . LYS B 2 284 ? 284.666 285.598 266.175 1.00 48.79  ? 282 LYS B CG  1 
ATOM   5561  C  CD  . LYS B 2 284 ? 285.497 286.776 265.706 1.00 61.78  ? 282 LYS B CD  1 
ATOM   5562  C  CE  . LYS B 2 284 ? 286.682 286.309 264.877 1.00 63.71  ? 282 LYS B CE  1 
ATOM   5563  N  NZ  . LYS B 2 284 ? 286.331 286.159 263.439 1.00 57.97  ? 282 LYS B NZ  1 
ATOM   5564  N  N   . GLU B 2 285 ? 286.602 281.552 267.455 1.00 40.26  ? 283 GLU B N   1 
ATOM   5565  C  CA  . GLU B 2 285 ? 287.491 280.418 267.207 1.00 38.02  ? 283 GLU B CA  1 
ATOM   5566  C  C   . GLU B 2 285 ? 286.703 279.173 266.809 1.00 38.99  ? 283 GLU B C   1 
ATOM   5567  O  O   . GLU B 2 285 ? 287.080 278.455 265.870 1.00 40.37  ? 283 GLU B O   1 
ATOM   5568  C  CB  . GLU B 2 285 ? 288.338 280.126 268.444 1.00 42.08  ? 283 GLU B CB  1 
ATOM   5569  C  CG  . GLU B 2 285 ? 289.403 281.156 268.748 1.00 47.34  ? 283 GLU B CG  1 
ATOM   5570  C  CD  . GLU B 2 285 ? 290.352 280.694 269.835 1.00 56.91  ? 283 GLU B CD  1 
ATOM   5571  O  OE1 . GLU B 2 285 ? 289.874 280.129 270.841 1.00 52.28  ? 283 GLU B OE1 1 
ATOM   5572  O  OE2 . GLU B 2 285 ? 291.575 280.899 269.689 1.00 64.74  ? 283 GLU B OE2 1 
ATOM   5573  N  N   . LEU B 2 286 ? 285.613 278.892 267.525 1.00 35.21  ? 284 LEU B N   1 
ATOM   5574  C  CA  . LEU B 2 286 ? 284.810 277.710 267.214 1.00 32.47  ? 284 LEU B CA  1 
ATOM   5575  C  C   . LEU B 2 286 ? 284.194 277.815 265.822 1.00 38.24  ? 284 LEU B C   1 
ATOM   5576  O  O   . LEU B 2 286 ? 284.257 276.870 265.017 1.00 42.29  ? 284 LEU B O   1 
ATOM   5577  C  CB  . LEU B 2 286 ? 283.724 277.526 268.273 1.00 28.06  ? 284 LEU B CB  1 
ATOM   5578  C  CG  . LEU B 2 286 ? 284.185 277.167 269.686 1.00 30.91  ? 284 LEU B CG  1 
ATOM   5579  C  CD1 . LEU B 2 286 ? 283.090 277.460 270.696 1.00 29.09  ? 284 LEU B CD1 1 
ATOM   5580  C  CD2 . LEU B 2 286 ? 284.604 275.708 269.762 1.00 28.72  ? 284 LEU B CD2 1 
ATOM   5581  N  N   . GLN B 2 287 ? 283.595 278.968 265.517 1.00 38.41  ? 285 GLN B N   1 
ATOM   5582  C  CA  . GLN B 2 287 ? 283.040 279.172 264.186 1.00 35.37  ? 285 GLN B CA  1 
ATOM   5583  C  C   . GLN B 2 287 ? 284.123 279.110 263.118 1.00 38.18  ? 285 GLN B C   1 
ATOM   5584  O  O   . GLN B 2 287 ? 283.863 278.660 261.999 1.00 39.03  ? 285 GLN B O   1 
ATOM   5585  C  CB  . GLN B 2 287 ? 282.300 280.508 264.123 1.00 39.10  ? 285 GLN B CB  1 
ATOM   5586  C  CG  . GLN B 2 287 ? 281.340 280.626 262.953 1.00 45.11  ? 285 GLN B CG  1 
ATOM   5587  C  CD  . GLN B 2 287 ? 280.319 279.507 262.922 1.00 53.56  ? 285 GLN B CD  1 
ATOM   5588  O  OE1 . GLN B 2 287 ? 279.849 279.051 263.965 1.00 50.04  ? 285 GLN B OE1 1 
ATOM   5589  N  NE2 . GLN B 2 287 ? 279.974 279.055 261.723 1.00 50.94  ? 285 GLN B NE2 1 
ATOM   5590  N  N   . GLY B 2 288 ? 285.338 279.551 263.444 1.00 36.09  ? 286 GLY B N   1 
ATOM   5591  C  CA  . GLY B 2 288 ? 286.421 279.491 262.480 1.00 36.50  ? 286 GLY B CA  1 
ATOM   5592  C  C   . GLY B 2 288 ? 286.833 278.070 262.162 1.00 38.62  ? 286 GLY B C   1 
ATOM   5593  O  O   . GLY B 2 288 ? 287.094 277.738 261.005 1.00 44.47  ? 286 GLY B O   1 
ATOM   5594  N  N   . PHE B 2 289 ? 286.902 277.212 263.180 1.00 37.22  ? 287 PHE B N   1 
ATOM   5595  C  CA  . PHE B 2 289 ? 287.135 275.796 262.907 1.00 35.87  ? 287 PHE B CA  1 
ATOM   5596  C  C   . PHE B 2 289 ? 286.041 275.233 262.006 1.00 35.77  ? 287 PHE B C   1 
ATOM   5597  O  O   . PHE B 2 289 ? 286.323 274.607 260.970 1.00 37.91  ? 287 PHE B O   1 
ATOM   5598  C  CB  . PHE B 2 289 ? 287.217 275.000 264.210 1.00 33.95  ? 287 PHE B CB  1 
ATOM   5599  C  CG  . PHE B 2 289 ? 287.344 273.518 263.999 1.00 31.16  ? 287 PHE B CG  1 
ATOM   5600  C  CD1 . PHE B 2 289 ? 288.583 272.936 263.794 1.00 31.94  ? 287 PHE B CD1 1 
ATOM   5601  C  CD2 . PHE B 2 289 ? 286.221 272.707 263.992 1.00 29.84  ? 287 PHE B CD2 1 
ATOM   5602  C  CE1 . PHE B 2 289 ? 288.700 271.577 263.590 1.00 29.03  ? 287 PHE B CE1 1 
ATOM   5603  C  CE2 . PHE B 2 289 ? 286.333 271.347 263.787 1.00 27.99  ? 287 PHE B CE2 1 
ATOM   5604  C  CZ  . PHE B 2 289 ? 287.574 270.782 263.588 1.00 27.70  ? 287 PHE B CZ  1 
ATOM   5605  N  N   . ARG B 2 290 ? 284.778 275.471 262.376 1.00 36.19  ? 288 ARG B N   1 
ATOM   5606  C  CA  . ARG B 2 290 ? 283.677 274.945 261.572 1.00 35.91  ? 288 ARG B CA  1 
ATOM   5607  C  C   . ARG B 2 290 ? 283.772 275.412 260.124 1.00 36.09  ? 288 ARG B C   1 
ATOM   5608  O  O   . ARG B 2 290 ? 283.572 274.621 259.195 1.00 38.93  ? 288 ARG B O   1 
ATOM   5609  C  CB  . ARG B 2 290 ? 282.332 275.352 262.169 1.00 40.33  ? 288 ARG B CB  1 
ATOM   5610  C  CG  . ARG B 2 290 ? 282.154 274.995 263.628 1.00 45.12  ? 288 ARG B CG  1 
ATOM   5611  C  CD  . ARG B 2 290 ? 280.698 275.131 264.031 1.00 47.33  ? 288 ARG B CD  1 
ATOM   5612  N  NE  . ARG B 2 290 ? 279.815 274.439 263.100 1.00 47.51  ? 288 ARG B NE  1 
ATOM   5613  C  CZ  . ARG B 2 290 ? 278.753 273.731 263.461 1.00 47.19  ? 288 ARG B CZ  1 
ATOM   5614  N  NH1 . ARG B 2 290 ? 278.410 273.600 264.731 1.00 44.47  ? 288 ARG B NH1 1 
ATOM   5615  N  NH2 . ARG B 2 290 ? 278.020 273.139 262.523 1.00 42.95  ? 288 ARG B NH2 1 
ATOM   5616  N  N   . ASP B 2 291 ? 284.069 276.695 259.910 1.00 37.69  ? 289 ASP B N   1 
ATOM   5617  C  CA  . ASP B 2 291 ? 284.106 277.228 258.552 1.00 38.43  ? 289 ASP B CA  1 
ATOM   5618  C  C   . ASP B 2 291 ? 285.318 276.717 257.784 1.00 41.50  ? 289 ASP B C   1 
ATOM   5619  O  O   . ASP B 2 291 ? 285.220 276.426 256.586 1.00 42.27  ? 289 ASP B O   1 
ATOM   5620  C  CB  . ASP B 2 291 ? 284.098 278.755 258.589 1.00 41.89  ? 289 ASP B CB  1 
ATOM   5621  C  CG  . ASP B 2 291 ? 282.817 279.318 259.175 1.00 54.60  ? 289 ASP B CG  1 
ATOM   5622  O  OD1 . ASP B 2 291 ? 281.751 278.689 258.999 1.00 53.44  ? 289 ASP B OD1 1 
ATOM   5623  O  OD2 . ASP B 2 291 ? 282.876 280.392 259.810 1.00 56.89  ? 289 ASP B OD2 1 
ATOM   5624  N  N   . GLY B 2 292 ? 286.467 276.597 258.451 1.00 38.28  ? 290 GLY B N   1 
ATOM   5625  C  CA  . GLY B 2 292 ? 287.659 276.103 257.792 1.00 36.48  ? 290 GLY B CA  1 
ATOM   5626  C  C   . GLY B 2 292 ? 287.606 274.632 257.457 1.00 32.99  ? 290 GLY B C   1 
ATOM   5627  O  O   . GLY B 2 292 ? 288.434 274.157 256.673 1.00 35.03  ? 290 GLY B O   1 
ATOM   5628  N  N   . LEU B 2 293 ? 286.657 273.894 258.038 1.00 35.51  ? 291 LEU B N   1 
ATOM   5629  C  CA  . LEU B 2 293 ? 286.501 272.494 257.653 1.00 30.29  ? 291 LEU B CA  1 
ATOM   5630  C  C   . LEU B 2 293 ? 286.264 272.339 256.153 1.00 28.19  ? 291 LEU B C   1 
ATOM   5631  O  O   . LEU B 2 293 ? 286.749 271.382 255.539 1.00 28.74  ? 291 LEU B O   1 
ATOM   5632  C  CB  . LEU B 2 293 ? 285.356 271.851 258.432 1.00 26.51  ? 291 LEU B CB  1 
ATOM   5633  C  CG  . LEU B 2 293 ? 285.635 271.447 259.876 1.00 29.21  ? 291 LEU B CG  1 
ATOM   5634  C  CD1 . LEU B 2 293 ? 284.417 270.759 260.462 1.00 27.37  ? 291 LEU B CD1 1 
ATOM   5635  C  CD2 . LEU B 2 293 ? 286.858 270.550 259.961 1.00 25.75  ? 291 LEU B CD2 1 
ATOM   5636  N  N   . PHE B 2 294 ? 285.528 273.264 255.542 1.00 32.45  ? 292 PHE B N   1 
ATOM   5637  C  CA  . PHE B 2 294 ? 285.015 273.072 254.193 1.00 30.29  ? 292 PHE B CA  1 
ATOM   5638  C  C   . PHE B 2 294 ? 285.526 274.150 253.247 1.00 29.34  ? 292 PHE B C   1 
ATOM   5639  O  O   . PHE B 2 294 ? 285.891 275.251 253.668 1.00 33.82  ? 292 PHE B O   1 
ATOM   5640  C  CB  . PHE B 2 294 ? 283.487 273.049 254.201 1.00 24.47  ? 292 PHE B CB  1 
ATOM   5641  C  CG  . PHE B 2 294 ? 282.915 272.023 255.129 1.00 25.18  ? 292 PHE B CG  1 
ATOM   5642  C  CD1 . PHE B 2 294 ? 282.998 270.675 254.828 1.00 24.97  ? 292 PHE B CD1 1 
ATOM   5643  C  CD2 . PHE B 2 294 ? 282.321 272.402 256.318 1.00 26.84  ? 292 PHE B CD2 1 
ATOM   5644  C  CE1 . PHE B 2 294 ? 282.482 269.728 255.685 1.00 26.64  ? 292 PHE B CE1 1 
ATOM   5645  C  CE2 . PHE B 2 294 ? 281.807 271.460 257.181 1.00 26.37  ? 292 PHE B CE2 1 
ATOM   5646  C  CZ  . PHE B 2 294 ? 281.887 270.122 256.864 1.00 26.52  ? 292 PHE B CZ  1 
ATOM   5647  N  N   . VAL B 2 295 ? 285.554 273.813 251.957 1.00 33.99  ? 293 VAL B N   1 
ATOM   5648  C  CA  . VAL B 2 295 ? 286.189 274.648 250.943 1.00 39.03  ? 293 VAL B CA  1 
ATOM   5649  C  C   . VAL B 2 295 ? 285.228 274.938 249.798 1.00 45.54  ? 293 VAL B C   1 
ATOM   5650  O  O   . VAL B 2 295 ? 285.650 275.368 248.719 1.00 55.10  ? 293 VAL B O   1 
ATOM   5651  C  CB  . VAL B 2 295 ? 287.470 273.980 250.411 1.00 36.21  ? 293 VAL B CB  1 
ATOM   5652  C  CG1 . VAL B 2 295 ? 288.291 273.416 251.558 1.00 31.98  ? 293 VAL B CG1 1 
ATOM   5653  C  CG2 . VAL B 2 295 ? 287.123 272.891 249.403 1.00 29.11  ? 293 VAL B CG2 1 
ATOM   5654  N  N   . THR B 2 296 ? 283.933 274.710 250.014 1.00 46.02  ? 294 THR B N   1 
ATOM   5655  C  CA  . THR B 2 296 ? 282.970 274.852 248.929 1.00 51.61  ? 294 THR B CA  1 
ATOM   5656  C  C   . THR B 2 296 ? 282.606 276.302 248.635 1.00 60.92  ? 294 THR B C   1 
ATOM   5657  O  O   . THR B 2 296 ? 281.892 276.556 247.660 1.00 60.94  ? 294 THR B O   1 
ATOM   5658  C  CB  . THR B 2 296 ? 281.697 274.059 249.240 1.00 50.95  ? 294 THR B CB  1 
ATOM   5659  O  OG1 . THR B 2 296 ? 281.024 273.735 248.018 1.00 46.21  ? 294 THR B OG1 1 
ATOM   5660  C  CG2 . THR B 2 296 ? 280.765 274.871 250.123 1.00 53.45  ? 294 THR B CG2 1 
ATOM   5661  N  N   . GLN B 2 297 ? 283.079 277.250 249.438 1.00 61.54  ? 295 GLN B N   1 
ATOM   5662  C  CA  . GLN B 2 297 ? 282.787 278.666 249.256 1.00 64.34  ? 295 GLN B CA  1 
ATOM   5663  C  C   . GLN B 2 297 ? 284.071 279.473 249.105 1.00 73.85  ? 295 GLN B C   1 
ATOM   5664  O  O   . GLN B 2 297 ? 284.221 280.551 249.682 1.00 80.23  ? 295 GLN B O   1 
ATOM   5665  C  CB  . GLN B 2 297 ? 281.951 279.199 250.415 1.00 64.83  ? 295 GLN B CB  1 
ATOM   5666  C  CG  . GLN B 2 297 ? 280.958 278.195 250.964 1.00 70.45  ? 295 GLN B CG  1 
ATOM   5667  C  CD  . GLN B 2 297 ? 280.050 278.793 252.015 1.00 77.34  ? 295 GLN B CD  1 
ATOM   5668  O  OE1 . GLN B 2 297 ? 280.400 279.775 252.668 1.00 75.99  ? 295 GLN B OE1 1 
ATOM   5669  N  NE2 . GLN B 2 297 ? 278.874 278.201 252.187 1.00 74.58  ? 295 GLN B NE2 1 
ATOM   5670  N  N   . ASP B 2 298 ? 285.015 278.953 248.321 1.00 75.39  ? 296 ASP B N   1 
ATOM   5671  C  CA  . ASP B 2 298 ? 286.311 279.591 248.092 1.00 78.82  ? 296 ASP B CA  1 
ATOM   5672  C  C   . ASP B 2 298 ? 286.505 279.715 246.584 1.00 85.71  ? 296 ASP B C   1 
ATOM   5673  O  O   . ASP B 2 298 ? 287.008 278.794 245.937 1.00 85.46  ? 296 ASP B O   1 
ATOM   5674  C  CB  . ASP B 2 298 ? 287.435 278.794 248.743 1.00 77.84  ? 296 ASP B CB  1 
ATOM   5675  C  CG  . ASP B 2 298 ? 287.860 279.371 250.077 1.00 89.96  ? 296 ASP B CG  1 
ATOM   5676  O  OD1 . ASP B 2 298 ? 288.212 280.569 250.121 1.00 91.97  ? 296 ASP B OD1 1 
ATOM   5677  O  OD2 . ASP B 2 298 ? 287.843 278.628 251.080 1.00 85.78  ? 296 ASP B OD2 1 
ATOM   5678  N  N   . THR B 2 299 ? 286.110 280.861 246.030 1.00 85.97  ? 297 THR B N   1 
ATOM   5679  C  CA  . THR B 2 299 ? 286.155 281.099 244.594 1.00 86.39  ? 297 THR B CA  1 
ATOM   5680  C  C   . THR B 2 299 ? 287.499 281.657 244.129 1.00 84.24  ? 297 THR B C   1 
ATOM   5681  O  O   . THR B 2 299 ? 287.567 282.283 243.065 1.00 83.18  ? 297 THR B O   1 
ATOM   5682  C  CB  . THR B 2 299 ? 285.014 282.036 244.187 1.00 87.87  ? 297 THR B CB  1 
ATOM   5683  O  OG1 . THR B 2 299 ? 285.137 282.389 242.804 1.00 92.26  ? 297 THR B OG1 1 
ATOM   5684  C  CG2 . THR B 2 299 ? 285.030 283.295 245.038 1.00 90.73  ? 297 THR B CG2 1 
ATOM   5685  N  N   . THR B 2 300 ? 288.568 281.437 244.892 1.00 83.25  ? 298 THR B N   1 
ATOM   5686  C  CA  . THR B 2 300 ? 289.892 281.918 244.514 1.00 83.86  ? 298 THR B CA  1 
ATOM   5687  C  C   . THR B 2 300 ? 290.550 281.058 243.441 1.00 82.74  ? 298 THR B C   1 
ATOM   5688  O  O   . THR B 2 300 ? 291.745 281.228 243.177 1.00 82.48  ? 298 THR B O   1 
ATOM   5689  C  CB  . THR B 2 300 ? 290.803 281.993 245.742 1.00 88.93  ? 298 THR B CB  1 
ATOM   5690  O  OG1 . THR B 2 300 ? 291.472 280.738 245.923 1.00 83.70  ? 298 THR B OG1 1 
ATOM   5691  C  CG2 . THR B 2 300 ? 289.993 282.314 246.988 1.00 89.50  ? 298 THR B CG2 1 
ATOM   5692  N  N   . TRP B 2 301 ? 289.804 280.148 242.824 1.00 80.11  ? 299 TRP B N   1 
ATOM   5693  C  CA  . TRP B 2 301 ? 290.332 279.308 241.756 1.00 77.74  ? 299 TRP B CA  1 
ATOM   5694  C  C   . TRP B 2 301 ? 290.173 279.985 240.399 1.00 80.11  ? 299 TRP B C   1 
ATOM   5695  O  O   . TRP B 2 301 ? 289.329 280.864 240.228 1.00 77.21  ? 299 TRP B O   1 
ATOM   5696  C  CB  . TRP B 2 301 ? 289.634 277.946 241.751 1.00 68.89  ? 299 TRP B CB  1 
ATOM   5697  C  CG  . TRP B 2 301 ? 288.154 278.025 241.984 1.00 65.79  ? 299 TRP B CG  1 
ATOM   5698  C  CD1 . TRP B 2 301 ? 287.518 278.037 243.188 1.00 65.08  ? 299 TRP B CD1 1 
ATOM   5699  C  CD2 . TRP B 2 301 ? 287.128 278.107 240.988 1.00 64.59  ? 299 TRP B CD2 1 
ATOM   5700  N  NE1 . TRP B 2 301 ? 286.160 278.120 243.007 1.00 60.58  ? 299 TRP B NE1 1 
ATOM   5701  C  CE2 . TRP B 2 301 ? 285.894 278.165 241.664 1.00 62.47  ? 299 TRP B CE2 1 
ATOM   5702  C  CE3 . TRP B 2 301 ? 287.132 278.138 239.590 1.00 60.77  ? 299 TRP B CE3 1 
ATOM   5703  C  CZ2 . TRP B 2 301 ? 284.677 278.249 240.992 1.00 57.01  ? 299 TRP B CZ2 1 
ATOM   5704  C  CZ3 . TRP B 2 301 ? 285.922 278.223 238.925 1.00 57.49  ? 299 TRP B CZ3 1 
ATOM   5705  C  CH2 . TRP B 2 301 ? 284.712 278.277 239.626 1.00 56.90  ? 299 TRP B CH2 1 
ATOM   5706  N  N   . GLY C 1 32  ? 345.741 229.469 237.572 1.00 82.65  ? 32  GLY C N   1 
ATOM   5707  C  CA  . GLY C 1 32  ? 344.581 230.330 237.711 1.00 91.12  ? 32  GLY C CA  1 
ATOM   5708  C  C   . GLY C 1 32  ? 344.471 231.372 236.615 1.00 99.20  ? 32  GLY C C   1 
ATOM   5709  O  O   . GLY C 1 32  ? 343.812 231.152 235.600 1.00 97.06  ? 32  GLY C O   1 
ATOM   5710  N  N   . GLY C 1 33  ? 345.120 232.518 236.825 1.00 101.70 ? 33  GLY C N   1 
ATOM   5711  C  CA  . GLY C 1 33  ? 345.130 233.601 235.870 1.00 97.00  ? 33  GLY C CA  1 
ATOM   5712  C  C   . GLY C 1 33  ? 344.677 234.890 236.517 1.00 96.29  ? 33  GLY C C   1 
ATOM   5713  O  O   . GLY C 1 33  ? 344.739 235.051 237.741 1.00 88.91  ? 33  GLY C O   1 
ATOM   5714  N  N   . GLU C 1 34  ? 344.213 235.814 235.681 1.00 99.28  ? 34  GLU C N   1 
ATOM   5715  C  CA  . GLU C 1 34  ? 343.775 237.118 236.149 1.00 95.41  ? 34  GLU C CA  1 
ATOM   5716  C  C   . GLU C 1 34  ? 342.397 237.021 236.800 1.00 90.48  ? 34  GLU C C   1 
ATOM   5717  O  O   . GLU C 1 34  ? 341.725 235.987 236.759 1.00 87.76  ? 34  GLU C O   1 
ATOM   5718  C  CB  . GLU C 1 34  ? 343.755 238.121 234.997 1.00 93.82  ? 34  GLU C CB  1 
ATOM   5719  C  CG  . GLU C 1 34  ? 345.085 238.257 234.275 1.00 98.15  ? 34  GLU C CG  1 
ATOM   5720  C  CD  . GLU C 1 34  ? 345.987 239.300 234.906 1.00 101.54 ? 34  GLU C CD  1 
ATOM   5721  O  OE1 . GLU C 1 34  ? 345.785 239.623 236.095 1.00 97.56  ? 34  GLU C OE1 1 
ATOM   5722  O  OE2 . GLU C 1 34  ? 346.899 239.797 234.212 1.00 105.68 ? 34  GLU C OE2 1 
ATOM   5723  N  N   . LEU C 1 35  ? 341.974 238.130 237.410 1.00 87.55  ? 35  LEU C N   1 
ATOM   5724  C  CA  . LEU C 1 35  ? 340.726 238.173 238.170 1.00 82.32  ? 35  LEU C CA  1 
ATOM   5725  C  C   . LEU C 1 35  ? 339.588 238.613 237.253 1.00 82.78  ? 35  LEU C C   1 
ATOM   5726  O  O   . LEU C 1 35  ? 339.212 239.784 237.183 1.00 80.61  ? 35  LEU C O   1 
ATOM   5727  C  CB  . LEU C 1 35  ? 340.864 239.096 239.374 1.00 75.32  ? 35  LEU C CB  1 
ATOM   5728  C  CG  . LEU C 1 35  ? 339.580 239.342 240.168 1.00 70.05  ? 35  LEU C CG  1 
ATOM   5729  C  CD1 . LEU C 1 35  ? 339.176 238.092 240.934 1.00 65.36  ? 35  LEU C CD1 1 
ATOM   5730  C  CD2 . LEU C 1 35  ? 339.745 240.524 241.110 1.00 60.33  ? 35  LEU C CD2 1 
ATOM   5731  N  N   . THR C 1 36  ? 339.032 237.641 236.537 1.00 80.94  ? 36  THR C N   1 
ATOM   5732  C  CA  . THR C 1 36  ? 337.804 237.860 235.786 1.00 80.77  ? 36  THR C CA  1 
ATOM   5733  C  C   . THR C 1 36  ? 336.626 237.776 236.756 1.00 79.77  ? 36  THR C C   1 
ATOM   5734  O  O   . THR C 1 36  ? 336.801 237.709 237.976 1.00 77.68  ? 36  THR C O   1 
ATOM   5735  C  CB  . THR C 1 36  ? 337.694 236.861 234.636 1.00 82.09  ? 36  THR C CB  1 
ATOM   5736  O  OG1 . THR C 1 36  ? 337.443 235.549 235.155 1.00 84.26  ? 36  THR C OG1 1 
ATOM   5737  C  CG2 . THR C 1 36  ? 338.981 236.841 233.826 1.00 80.85  ? 36  THR C CG2 1 
ATOM   5738  N  N   . GLY C 1 37  ? 335.405 237.782 236.231 1.00 78.94  ? 37  GLY C N   1 
ATOM   5739  C  CA  . GLY C 1 37  ? 334.209 237.727 237.050 1.00 72.38  ? 37  GLY C CA  1 
ATOM   5740  C  C   . GLY C 1 37  ? 333.445 236.435 236.841 1.00 70.23  ? 37  GLY C C   1 
ATOM   5741  O  O   . GLY C 1 37  ? 333.492 235.837 235.764 1.00 73.56  ? 37  GLY C O   1 
ATOM   5742  N  N   . ALA C 1 38  ? 332.741 236.002 237.886 1.00 65.19  ? 38  ALA C N   1 
ATOM   5743  C  CA  . ALA C 1 38  ? 331.850 234.848 237.810 1.00 65.70  ? 38  ALA C CA  1 
ATOM   5744  C  C   . ALA C 1 38  ? 330.430 235.372 237.618 1.00 67.75  ? 38  ALA C C   1 
ATOM   5745  O  O   . ALA C 1 38  ? 329.608 235.393 238.534 1.00 69.47  ? 38  ALA C O   1 
ATOM   5746  C  CB  . ALA C 1 38  ? 331.979 233.979 239.057 1.00 64.29  ? 38  ALA C CB  1 
ATOM   5747  N  N   . LYS C 1 39  ? 330.148 235.803 236.392 1.00 72.91  ? 39  LYS C N   1 
ATOM   5748  C  CA  . LYS C 1 39  ? 328.860 236.409 236.089 1.00 75.20  ? 39  LYS C CA  1 
ATOM   5749  C  C   . LYS C 1 39  ? 327.726 235.420 236.321 1.00 79.61  ? 39  LYS C C   1 
ATOM   5750  O  O   . LYS C 1 39  ? 327.854 234.223 236.051 1.00 84.37  ? 39  LYS C O   1 
ATOM   5751  C  CB  . LYS C 1 39  ? 328.838 236.901 234.643 1.00 75.42  ? 39  LYS C CB  1 
ATOM   5752  C  CG  . LYS C 1 39  ? 329.539 238.229 234.430 1.00 78.04  ? 39  LYS C CG  1 
ATOM   5753  C  CD  . LYS C 1 39  ? 329.647 238.557 232.952 1.00 85.57  ? 39  LYS C CD  1 
ATOM   5754  C  CE  . LYS C 1 39  ? 330.122 239.983 232.738 1.00 87.39  ? 39  LYS C CE  1 
ATOM   5755  N  NZ  . LYS C 1 39  ? 329.012 240.869 232.292 1.00 79.57  ? 39  LYS C NZ  1 
ATOM   5756  N  N   . LEU C 1 40  ? 326.609 235.931 236.828 1.00 77.81  ? 40  LEU C N   1 
ATOM   5757  C  CA  . LEU C 1 40  ? 325.412 235.133 237.030 1.00 80.13  ? 40  LEU C CA  1 
ATOM   5758  C  C   . LEU C 1 40  ? 324.606 235.054 235.735 1.00 84.60  ? 40  LEU C C   1 
ATOM   5759  O  O   . LEU C 1 40  ? 324.911 235.711 234.737 1.00 82.69  ? 40  LEU C O   1 
ATOM   5760  C  CB  . LEU C 1 40  ? 324.564 235.719 238.158 1.00 70.72  ? 40  LEU C CB  1 
ATOM   5761  C  CG  . LEU C 1 40  ? 325.075 235.488 239.581 1.00 68.62  ? 40  LEU C CG  1 
ATOM   5762  C  CD1 . LEU C 1 40  ? 324.117 236.080 240.600 1.00 59.21  ? 40  LEU C CD1 1 
ATOM   5763  C  CD2 . LEU C 1 40  ? 325.286 234.005 239.841 1.00 72.55  ? 40  LEU C CD2 1 
ATOM   5764  N  N   . SER C 1 41  ? 323.558 234.236 235.761 1.00 86.47  ? 41  SER C N   1 
ATOM   5765  C  CA  . SER C 1 41  ? 322.711 234.055 234.591 1.00 88.02  ? 41  SER C CA  1 
ATOM   5766  C  C   . SER C 1 41  ? 321.693 235.185 234.505 1.00 91.97  ? 41  SER C C   1 
ATOM   5767  O  O   . SER C 1 41  ? 321.051 235.532 235.501 1.00 96.70  ? 41  SER C O   1 
ATOM   5768  C  CB  . SER C 1 41  ? 322.004 232.702 234.648 1.00 90.84  ? 41  SER C CB  1 
ATOM   5769  O  OG  . SER C 1 41  ? 321.514 232.437 235.951 1.00 92.30  ? 41  SER C OG  1 
ATOM   5770  N  N   . SER C 1 42  ? 321.548 235.757 233.312 1.00 92.02  ? 42  SER C N   1 
ATOM   5771  C  CA  . SER C 1 42  ? 320.649 236.888 233.125 1.00 92.95  ? 42  SER C CA  1 
ATOM   5772  C  C   . SER C 1 42  ? 319.211 236.486 233.423 1.00 93.11  ? 42  SER C C   1 
ATOM   5773  O  O   . SER C 1 42  ? 318.740 235.435 232.981 1.00 95.67  ? 42  SER C O   1 
ATOM   5774  C  CB  . SER C 1 42  ? 320.762 237.420 231.697 1.00 93.02  ? 42  SER C CB  1 
ATOM   5775  O  OG  . SER C 1 42  ? 320.468 236.405 230.753 1.00 93.13  ? 42  SER C OG  1 
ATOM   5776  N  N   . TRP C 1 43  ? 318.514 237.331 234.174 1.00 93.08  ? 43  TRP C N   1 
ATOM   5777  C  CA  . TRP C 1 43  ? 317.118 237.112 234.519 1.00 97.60  ? 43  TRP C CA  1 
ATOM   5778  C  C   . TRP C 1 43  ? 316.207 237.904 233.584 1.00 99.07  ? 43  TRP C C   1 
ATOM   5779  O  O   . TRP C 1 43  ? 316.653 238.727 232.782 1.00 96.33  ? 43  TRP C O   1 
ATOM   5780  C  CB  . TRP C 1 43  ? 316.855 237.506 235.975 1.00 96.39  ? 43  TRP C CB  1 
ATOM   5781  C  CG  . TRP C 1 43  ? 317.559 236.646 236.979 1.00 97.14  ? 43  TRP C CG  1 
ATOM   5782  C  CD1 . TRP C 1 43  ? 318.292 235.524 236.727 1.00 98.38  ? 43  TRP C CD1 1 
ATOM   5783  C  CD2 . TRP C 1 43  ? 317.597 236.841 238.397 1.00 99.64  ? 43  TRP C CD2 1 
ATOM   5784  N  NE1 . TRP C 1 43  ? 318.784 235.008 237.901 1.00 98.94  ? 43  TRP C NE1 1 
ATOM   5785  C  CE2 . TRP C 1 43  ? 318.371 235.798 238.941 1.00 100.09 ? 43  TRP C CE2 1 
ATOM   5786  C  CE3 . TRP C 1 43  ? 317.050 237.796 239.259 1.00 99.27  ? 43  TRP C CE3 1 
ATOM   5787  C  CZ2 . TRP C 1 43  ? 318.614 235.685 240.308 1.00 95.93  ? 43  TRP C CZ2 1 
ATOM   5788  C  CZ3 . TRP C 1 43  ? 317.292 237.681 240.616 1.00 98.80  ? 43  TRP C CZ3 1 
ATOM   5789  C  CH2 . TRP C 1 43  ? 318.066 236.633 241.127 1.00 96.82  ? 43  TRP C CH2 1 
ATOM   5790  N  N   . ASN C 1 44  ? 314.908 237.639 233.698 1.00 102.37 ? 44  ASN C N   1 
ATOM   5791  C  CA  . ASN C 1 44  ? 313.883 238.354 232.950 1.00 99.83  ? 44  ASN C CA  1 
ATOM   5792  C  C   . ASN C 1 44  ? 312.893 238.968 233.928 1.00 99.34  ? 44  ASN C C   1 
ATOM   5793  O  O   . ASN C 1 44  ? 312.306 238.257 234.751 1.00 98.48  ? 44  ASN C O   1 
ATOM   5794  C  CB  . ASN C 1 44  ? 313.157 237.423 231.976 1.00 99.14  ? 44  ASN C CB  1 
ATOM   5795  C  CG  . ASN C 1 44  ? 312.043 238.124 231.225 1.00 102.62 ? 44  ASN C CG  1 
ATOM   5796  O  OD1 . ASN C 1 44  ? 310.898 237.670 231.222 1.00 102.14 ? 44  ASN C OD1 1 
ATOM   5797  N  ND2 . ASN C 1 44  ? 312.372 239.239 230.582 1.00 101.53 ? 44  ASN C ND2 1 
ATOM   5798  N  N   . GLU C 1 45  ? 312.699 240.283 233.829 1.00 95.20  ? 45  GLU C N   1 
ATOM   5799  C  CA  . GLU C 1 45  ? 311.822 240.992 234.748 1.00 91.22  ? 45  GLU C CA  1 
ATOM   5800  C  C   . GLU C 1 45  ? 310.453 241.173 234.111 1.00 89.80  ? 45  GLU C C   1 
ATOM   5801  O  O   . GLU C 1 45  ? 310.335 241.910 233.120 1.00 84.26  ? 45  GLU C O   1 
ATOM   5802  C  CB  . GLU C 1 45  ? 312.420 242.346 235.122 1.00 86.19  ? 45  GLU C CB  1 
ATOM   5803  C  CG  . GLU C 1 45  ? 311.397 243.457 235.294 1.00 82.89  ? 45  GLU C CG  1 
ATOM   5804  C  CD  . GLU C 1 45  ? 310.683 243.391 236.629 1.00 79.59  ? 45  GLU C CD  1 
ATOM   5805  O  OE1 . GLU C 1 45  ? 311.117 242.607 237.498 1.00 84.04  ? 45  GLU C OE1 1 
ATOM   5806  O  OE2 . GLU C 1 45  ? 309.688 244.121 236.808 1.00 69.46  ? 45  GLU C OE2 1 
ATOM   5807  N  N   . PRO C 1 46  ? 309.402 240.532 234.626 1.00 89.42  ? 46  PRO C N   1 
ATOM   5808  C  CA  . PRO C 1 46  ? 308.051 240.737 234.080 1.00 84.09  ? 46  PRO C CA  1 
ATOM   5809  C  C   . PRO C 1 46  ? 307.411 241.976 234.691 1.00 77.90  ? 46  PRO C C   1 
ATOM   5810  O  O   . PRO C 1 46  ? 307.242 242.065 235.909 1.00 74.86  ? 46  PRO C O   1 
ATOM   5811  C  CB  . PRO C 1 46  ? 307.304 239.458 234.486 1.00 78.06  ? 46  PRO C CB  1 
ATOM   5812  C  CG  . PRO C 1 46  ? 308.315 238.585 235.209 1.00 81.58  ? 46  PRO C CG  1 
ATOM   5813  C  CD  . PRO C 1 46  ? 309.421 239.481 235.652 1.00 84.71  ? 46  PRO C CD  1 
ATOM   5814  N  N   . SER C 1 47  ? 307.055 242.930 233.843 1.00 75.15  ? 47  SER C N   1 
ATOM   5815  C  CA  . SER C 1 47  ? 306.392 244.142 234.310 1.00 67.42  ? 47  SER C CA  1 
ATOM   5816  C  C   . SER C 1 47  ? 304.947 243.824 234.674 1.00 67.22  ? 47  SER C C   1 
ATOM   5817  O  O   . SER C 1 47  ? 304.199 243.328 233.821 1.00 67.38  ? 47  SER C O   1 
ATOM   5818  C  CB  . SER C 1 47  ? 306.449 245.225 233.237 1.00 61.84  ? 47  SER C CB  1 
ATOM   5819  O  OG  . SER C 1 47  ? 305.486 246.236 233.476 1.00 60.62  ? 47  SER C OG  1 
ATOM   5820  N  N   . PRO C 1 48  ? 304.514 244.082 235.904 1.00 60.85  ? 48  PRO C N   1 
ATOM   5821  C  CA  . PRO C 1 48  ? 303.155 243.698 236.298 1.00 57.06  ? 48  PRO C CA  1 
ATOM   5822  C  C   . PRO C 1 48  ? 302.104 244.480 235.526 1.00 53.45  ? 48  PRO C C   1 
ATOM   5823  O  O   . PRO C 1 48  ? 302.305 245.635 235.145 1.00 54.11  ? 48  PRO C O   1 
ATOM   5824  C  CB  . PRO C 1 48  ? 303.105 244.027 237.797 1.00 48.88  ? 48  PRO C CB  1 
ATOM   5825  C  CG  . PRO C 1 48  ? 304.524 244.310 238.201 1.00 46.54  ? 48  PRO C CG  1 
ATOM   5826  C  CD  . PRO C 1 48  ? 305.218 244.798 236.977 1.00 49.26  ? 48  PRO C CD  1 
ATOM   5827  N  N   . PHE C 1 49  ? 300.969 243.826 235.302 1.00 54.35  ? 49  PHE C N   1 
ATOM   5828  C  CA  . PHE C 1 49  ? 299.867 244.438 234.576 1.00 52.38  ? 49  PHE C CA  1 
ATOM   5829  C  C   . PHE C 1 49  ? 299.018 245.284 235.516 1.00 47.73  ? 49  PHE C C   1 
ATOM   5830  O  O   . PHE C 1 49  ? 298.723 244.880 236.644 1.00 48.78  ? 49  PHE C O   1 
ATOM   5831  C  CB  . PHE C 1 49  ? 299.011 243.360 233.911 1.00 49.26  ? 49  PHE C CB  1 
ATOM   5832  C  CG  . PHE C 1 49  ? 297.703 243.865 233.380 1.00 57.75  ? 49  PHE C CG  1 
ATOM   5833  C  CD1 . PHE C 1 49  ? 296.555 243.796 234.150 1.00 58.26  ? 49  PHE C CD1 1 
ATOM   5834  C  CD2 . PHE C 1 49  ? 297.621 244.409 232.111 1.00 56.81  ? 49  PHE C CD2 1 
ATOM   5835  C  CE1 . PHE C 1 49  ? 295.352 244.261 233.665 1.00 54.97  ? 49  PHE C CE1 1 
ATOM   5836  C  CE2 . PHE C 1 49  ? 296.420 244.877 231.620 1.00 55.76  ? 49  PHE C CE2 1 
ATOM   5837  C  CZ  . PHE C 1 49  ? 295.284 244.802 232.398 1.00 53.23  ? 49  PHE C CZ  1 
ATOM   5838  N  N   . GLY C 1 50  ? 298.628 246.466 235.045 1.00 42.75  ? 50  GLY C N   1 
ATOM   5839  C  CA  . GLY C 1 50  ? 297.864 247.385 235.861 1.00 38.08  ? 50  GLY C CA  1 
ATOM   5840  C  C   . GLY C 1 50  ? 298.682 248.202 236.831 1.00 36.83  ? 50  GLY C C   1 
ATOM   5841  O  O   . GLY C 1 50  ? 298.105 248.838 237.721 1.00 33.78  ? 50  GLY C O   1 
ATOM   5842  N  N   . MET C 1 51  ? 300.004 248.207 236.692 1.00 36.25  ? 51  MET C N   1 
ATOM   5843  C  CA  . MET C 1 51  ? 300.892 248.882 237.622 1.00 29.42  ? 51  MET C CA  1 
ATOM   5844  C  C   . MET C 1 51  ? 301.783 249.856 236.868 1.00 29.94  ? 51  MET C C   1 
ATOM   5845  O  O   . MET C 1 51  ? 302.134 249.633 235.706 1.00 35.52  ? 51  MET C O   1 
ATOM   5846  C  CB  . MET C 1 51  ? 301.758 247.875 238.389 1.00 28.04  ? 51  MET C CB  1 
ATOM   5847  C  CG  . MET C 1 51  ? 300.970 246.838 239.168 1.00 29.65  ? 51  MET C CG  1 
ATOM   5848  S  SD  . MET C 1 51  ? 301.949 246.020 240.440 1.00 37.95  ? 51  MET C SD  1 
ATOM   5849  C  CE  . MET C 1 51  ? 301.605 247.038 241.868 1.00 21.18  ? 51  MET C CE  1 
ATOM   5850  N  N   . ILE C 1 52  ? 302.142 250.942 237.541 1.00 27.11  ? 52  ILE C N   1 
ATOM   5851  C  CA  . ILE C 1 52  ? 303.098 251.905 237.020 1.00 25.91  ? 52  ILE C CA  1 
ATOM   5852  C  C   . ILE C 1 52  ? 304.356 251.850 237.875 1.00 22.85  ? 52  ILE C C   1 
ATOM   5853  O  O   . ILE C 1 52  ? 304.371 251.304 238.982 1.00 25.03  ? 52  ILE C O   1 
ATOM   5854  C  CB  . ILE C 1 52  ? 302.525 253.337 236.972 1.00 24.39  ? 52  ILE C CB  1 
ATOM   5855  C  CG1 . ILE C 1 52  ? 301.800 253.672 238.275 1.00 28.13  ? 52  ILE C CG1 1 
ATOM   5856  C  CG2 . ILE C 1 52  ? 301.587 253.493 235.793 1.00 26.18  ? 52  ILE C CG2 1 
ATOM   5857  C  CD1 . ILE C 1 52  ? 302.669 254.361 239.295 1.00 23.26  ? 52  ILE C CD1 1 
ATOM   5858  N  N   . GLN C 1 53  ? 305.430 252.419 237.342 1.00 25.18  ? 53  GLN C N   1 
ATOM   5859  C  CA  . GLN C 1 53  ? 306.728 252.417 238.000 1.00 24.92  ? 53  GLN C CA  1 
ATOM   5860  C  C   . GLN C 1 53  ? 306.943 253.740 238.722 1.00 26.97  ? 53  GLN C C   1 
ATOM   5861  O  O   . GLN C 1 53  ? 306.765 254.810 238.132 1.00 27.54  ? 53  GLN C O   1 
ATOM   5862  C  CB  . GLN C 1 53  ? 307.845 252.180 236.984 1.00 28.60  ? 53  GLN C CB  1 
ATOM   5863  C  CG  . GLN C 1 53  ? 309.239 252.412 237.528 1.00 34.90  ? 53  GLN C CG  1 
ATOM   5864  C  CD  . GLN C 1 53  ? 309.836 251.163 238.138 1.00 37.39  ? 53  GLN C CD  1 
ATOM   5865  O  OE1 . GLN C 1 53  ? 310.032 251.084 239.349 1.00 36.26  ? 53  GLN C OE1 1 
ATOM   5866  N  NE2 . GLN C 1 53  ? 310.128 250.177 237.299 1.00 39.52  ? 53  GLN C NE2 1 
ATOM   5867  N  N   . VAL C 1 54  ? 307.317 253.664 239.992 1.00 25.25  ? 54  VAL C N   1 
ATOM   5868  C  CA  . VAL C 1 54  ? 307.649 254.816 240.820 1.00 23.02  ? 54  VAL C CA  1 
ATOM   5869  C  C   . VAL C 1 54  ? 309.155 254.792 241.054 1.00 28.00  ? 54  VAL C C   1 
ATOM   5870  O  O   . VAL C 1 54  ? 309.668 253.834 241.651 1.00 28.25  ? 54  VAL C O   1 
ATOM   5871  C  CB  . VAL C 1 54  ? 306.883 254.798 242.152 1.00 21.08  ? 54  VAL C CB  1 
ATOM   5872  C  CG1 . VAL C 1 54  ? 307.134 256.077 242.928 1.00 20.51  ? 54  VAL C CG1 1 
ATOM   5873  C  CG2 . VAL C 1 54  ? 305.395 254.593 241.905 1.00 19.50  ? 54  VAL C CG2 1 
ATOM   5874  N  N   . PRO C 1 55  ? 309.895 255.797 240.601 1.00 27.96  ? 55  PRO C N   1 
ATOM   5875  C  CA  . PRO C 1 55  ? 311.353 255.770 240.731 1.00 22.08  ? 55  PRO C CA  1 
ATOM   5876  C  C   . PRO C 1 55  ? 311.812 256.037 242.156 1.00 24.29  ? 55  PRO C C   1 
ATOM   5877  O  O   . PRO C 1 55  ? 311.079 256.562 242.995 1.00 23.22  ? 55  PRO C O   1 
ATOM   5878  C  CB  . PRO C 1 55  ? 311.803 256.894 239.793 1.00 23.25  ? 55  PRO C CB  1 
ATOM   5879  C  CG  . PRO C 1 55  ? 310.670 257.853 239.816 1.00 22.35  ? 55  PRO C CG  1 
ATOM   5880  C  CD  . PRO C 1 55  ? 309.423 257.017 239.923 1.00 21.89  ? 55  PRO C CD  1 
ATOM   5881  N  N   . ARG C 1 56  ? 313.058 255.653 242.415 1.00 23.48  ? 56  ARG C N   1 
ATOM   5882  C  CA  . ARG C 1 56  ? 313.690 255.961 243.686 1.00 20.16  ? 56  ARG C CA  1 
ATOM   5883  C  C   . ARG C 1 56  ? 313.858 257.468 243.837 1.00 20.00  ? 56  ARG C C   1 
ATOM   5884  O  O   . ARG C 1 56  ? 313.969 258.205 242.854 1.00 21.69  ? 56  ARG C O   1 
ATOM   5885  C  CB  . ARG C 1 56  ? 315.047 255.269 243.783 1.00 20.24  ? 56  ARG C CB  1 
ATOM   5886  C  CG  . ARG C 1 56  ? 316.133 255.954 242.979 1.00 23.06  ? 56  ARG C CG  1 
ATOM   5887  C  CD  . ARG C 1 56  ? 317.461 255.240 243.104 1.00 25.36  ? 56  ARG C CD  1 
ATOM   5888  N  NE  . ARG C 1 56  ? 317.416 253.910 242.511 1.00 31.79  ? 56  ARG C NE  1 
ATOM   5889  C  CZ  . ARG C 1 56  ? 318.214 253.498 241.537 1.00 31.88  ? 56  ARG C CZ  1 
ATOM   5890  N  NH1 . ARG C 1 56  ? 319.137 254.290 241.018 1.00 32.14  ? 56  ARG C NH1 1 
ATOM   5891  N  NH2 . ARG C 1 56  ? 318.081 252.261 241.069 1.00 43.27  ? 56  ARG C NH2 1 
ATOM   5892  N  N   . GLY C 1 57  ? 313.865 257.929 245.080 1.00 17.03  ? 57  GLY C N   1 
ATOM   5893  C  CA  . GLY C 1 57  ? 313.961 259.355 245.309 1.00 15.80  ? 57  GLY C CA  1 
ATOM   5894  C  C   . GLY C 1 57  ? 313.860 259.679 246.780 1.00 16.48  ? 57  GLY C C   1 
ATOM   5895  O  O   . GLY C 1 57  ? 313.959 258.802 247.637 1.00 19.58  ? 57  GLY C O   1 
ATOM   5896  N  N   . SER C 1 58  ? 313.667 260.964 247.057 1.00 20.02  ? 58  SER C N   1 
ATOM   5897  C  CA  . SER C 1 58  ? 313.602 261.467 248.418 1.00 15.17  ? 58  SER C CA  1 
ATOM   5898  C  C   . SER C 1 58  ? 312.434 262.434 248.535 1.00 17.71  ? 58  SER C C   1 
ATOM   5899  O  O   . SER C 1 58  ? 312.021 263.053 247.552 1.00 22.89  ? 58  SER C O   1 
ATOM   5900  C  CB  . SER C 1 58  ? 314.913 262.159 248.821 1.00 14.93  ? 58  SER C CB  1 
ATOM   5901  O  OG  . SER C 1 58  ? 314.908 262.521 250.190 1.00 26.52  ? 58  SER C OG  1 
ATOM   5902  N  N   . ILE C 1 59  ? 311.896 262.548 249.748 1.00 16.50  ? 59  ILE C N   1 
ATOM   5903  C  CA  . ILE C 1 59  ? 310.788 263.460 250.007 1.00 17.09  ? 59  ILE C CA  1 
ATOM   5904  C  C   . ILE C 1 59  ? 310.745 263.753 251.496 1.00 20.98  ? 59  ILE C C   1 
ATOM   5905  O  O   . ILE C 1 59  ? 311.148 262.927 252.317 1.00 24.15  ? 59  ILE C O   1 
ATOM   5906  C  CB  . ILE C 1 59  ? 309.443 262.877 249.504 1.00 21.97  ? 59  ILE C CB  1 
ATOM   5907  C  CG1 . ILE C 1 59  ? 308.370 263.968 249.464 1.00 21.26  ? 59  ILE C CG1 1 
ATOM   5908  C  CG2 . ILE C 1 59  ? 308.995 261.723 250.383 1.00 18.69  ? 59  ILE C CG2 1 
ATOM   5909  C  CD1 . ILE C 1 59  ? 307.088 263.541 248.792 1.00 18.93  ? 59  ILE C CD1 1 
ATOM   5910  N  N   . VAL C 1 60  ? 310.241 264.934 251.844 1.00 23.36  ? 60  VAL C N   1 
ATOM   5911  C  CA  . VAL C 1 60  ? 310.040 265.315 253.237 1.00 24.35  ? 60  VAL C CA  1 
ATOM   5912  C  C   . VAL C 1 60  ? 308.615 264.916 253.608 1.00 25.77  ? 60  VAL C C   1 
ATOM   5913  O  O   . VAL C 1 60  ? 307.657 265.621 253.293 1.00 30.17  ? 60  VAL C O   1 
ATOM   5914  C  CB  . VAL C 1 60  ? 310.288 266.808 253.460 1.00 23.94  ? 60  VAL C CB  1 
ATOM   5915  C  CG1 . VAL C 1 60  ? 310.038 267.172 254.915 1.00 25.61  ? 60  VAL C CG1 1 
ATOM   5916  C  CG2 . VAL C 1 60  ? 311.702 267.180 253.050 1.00 19.08  ? 60  VAL C CG2 1 
ATOM   5917  N  N   . LEU C 1 61  ? 308.476 263.774 254.277 1.00 28.09  ? 61  LEU C N   1 
ATOM   5918  C  CA  . LEU C 1 61  ? 307.170 263.344 254.748 1.00 25.62  ? 61  LEU C CA  1 
ATOM   5919  C  C   . LEU C 1 61  ? 306.634 264.334 255.772 1.00 32.19  ? 61  LEU C C   1 
ATOM   5920  O  O   . LEU C 1 61  ? 307.384 264.869 256.593 1.00 36.17  ? 61  LEU C O   1 
ATOM   5921  C  CB  . LEU C 1 61  ? 307.264 261.952 255.373 1.00 22.98  ? 61  LEU C CB  1 
ATOM   5922  C  CG  . LEU C 1 61  ? 307.754 260.805 254.493 1.00 26.84  ? 61  LEU C CG  1 
ATOM   5923  C  CD1 . LEU C 1 61  ? 307.821 259.523 255.302 1.00 24.62  ? 61  LEU C CD1 1 
ATOM   5924  C  CD2 . LEU C 1 61  ? 306.857 260.632 253.281 1.00 24.62  ? 61  LEU C CD2 1 
ATOM   5925  N  N   . GLY C 1 62  ? 305.326 264.562 255.729 1.00 33.27  ? 62  GLY C N   1 
ATOM   5926  C  CA  . GLY C 1 62  ? 304.691 265.503 256.626 1.00 33.98  ? 62  GLY C CA  1 
ATOM   5927  C  C   . GLY C 1 62  ? 304.651 266.906 256.063 1.00 43.22  ? 62  GLY C C   1 
ATOM   5928  O  O   . GLY C 1 62  ? 305.160 267.206 254.980 1.00 47.07  ? 62  GLY C O   1 
ATOM   5929  N  N   . ASN C 1 63  ? 304.016 267.791 256.825 1.00 52.15  ? 63  ASN C N   1 
ATOM   5930  C  CA  . ASN C 1 63  ? 303.906 269.194 256.464 1.00 58.33  ? 63  ASN C CA  1 
ATOM   5931  C  C   . ASN C 1 63  ? 304.630 270.045 257.496 1.00 59.00  ? 63  ASN C C   1 
ATOM   5932  O  O   . ASN C 1 63  ? 304.682 269.706 258.682 1.00 56.00  ? 63  ASN C O   1 
ATOM   5933  C  CB  . ASN C 1 63  ? 302.440 269.636 256.352 1.00 51.91  ? 63  ASN C CB  1 
ATOM   5934  C  CG  . ASN C 1 63  ? 301.628 269.290 257.582 1.00 58.77  ? 63  ASN C CG  1 
ATOM   5935  O  OD1 . ASN C 1 63  ? 302.122 268.654 258.512 1.00 60.94  ? 63  ASN C OD1 1 
ATOM   5936  N  ND2 . ASN C 1 63  ? 300.368 269.708 257.592 1.00 61.46  ? 63  ASN C ND2 1 
ATOM   5937  N  N   . LYS C 1 64  ? 305.193 271.155 257.029 1.00 62.03  ? 64  LYS C N   1 
ATOM   5938  C  CA  . LYS C 1 64  ? 305.989 272.040 257.866 1.00 66.15  ? 64  LYS C CA  1 
ATOM   5939  C  C   . LYS C 1 64  ? 305.173 273.163 258.493 1.00 67.09  ? 64  LYS C C   1 
ATOM   5940  O  O   . LYS C 1 64  ? 305.728 273.958 259.258 1.00 67.42  ? 64  LYS C O   1 
ATOM   5941  C  CB  . LYS C 1 64  ? 307.148 272.628 257.052 1.00 67.01  ? 64  LYS C CB  1 
ATOM   5942  C  CG  . LYS C 1 64  ? 307.996 271.583 256.327 1.00 63.86  ? 64  LYS C CG  1 
ATOM   5943  C  CD  . LYS C 1 64  ? 307.353 271.149 255.012 1.00 64.59  ? 64  LYS C CD  1 
ATOM   5944  C  CE  . LYS C 1 64  ? 307.966 269.859 254.478 1.00 58.67  ? 64  LYS C CE  1 
ATOM   5945  N  NZ  . LYS C 1 64  ? 306.977 269.022 253.736 1.00 47.40  ? 64  LYS C NZ  1 
ATOM   5946  N  N   . GLU C 1 65  ? 303.878 273.249 258.195 1.00 67.23  ? 65  GLU C N   1 
ATOM   5947  C  CA  . GLU C 1 65  ? 303.002 274.246 258.792 1.00 67.37  ? 65  GLU C CA  1 
ATOM   5948  C  C   . GLU C 1 65  ? 301.760 273.561 259.342 1.00 69.16  ? 65  GLU C C   1 
ATOM   5949  O  O   . GLU C 1 65  ? 301.256 272.604 258.749 1.00 72.83  ? 65  GLU C O   1 
ATOM   5950  C  CB  . GLU C 1 65  ? 302.604 275.323 257.778 1.00 70.14  ? 65  GLU C CB  1 
ATOM   5951  C  CG  . GLU C 1 65  ? 303.727 275.727 256.838 1.00 80.57  ? 65  GLU C CG  1 
ATOM   5952  C  CD  . GLU C 1 65  ? 304.503 276.931 257.335 1.00 85.72  ? 65  GLU C CD  1 
ATOM   5953  O  OE1 . GLU C 1 65  ? 303.868 277.938 257.712 1.00 85.17  ? 65  GLU C OE1 1 
ATOM   5954  O  OE2 . GLU C 1 65  ? 305.751 276.870 257.346 1.00 80.39  ? 65  GLU C OE2 1 
ATOM   5955  N  N   . ALA C 1 66  ? 301.274 274.056 260.474 1.00 70.59  ? 66  ALA C N   1 
ATOM   5956  C  CA  . ALA C 1 66  ? 300.131 273.475 261.161 1.00 67.85  ? 66  ALA C CA  1 
ATOM   5957  C  C   . ALA C 1 66  ? 298.877 274.312 260.932 1.00 71.98  ? 66  ALA C C   1 
ATOM   5958  O  O   . ALA C 1 66  ? 298.931 275.463 260.491 1.00 74.44  ? 66  ALA C O   1 
ATOM   5959  C  CB  . ALA C 1 66  ? 300.419 273.343 262.659 1.00 65.51  ? 66  ALA C CB  1 
ATOM   5960  N  N   . ASP C 1 67  ? 297.728 273.707 261.239 1.00 71.34  ? 67  ASP C N   1 
ATOM   5961  C  CA  . ASP C 1 67  ? 296.457 274.412 261.103 1.00 70.30  ? 67  ASP C CA  1 
ATOM   5962  C  C   . ASP C 1 67  ? 296.271 275.435 262.215 1.00 71.88  ? 67  ASP C C   1 
ATOM   5963  O  O   . ASP C 1 67  ? 295.762 276.536 261.977 1.00 74.76  ? 67  ASP C O   1 
ATOM   5964  C  CB  . ASP C 1 67  ? 295.296 273.415 261.102 1.00 67.06  ? 67  ASP C CB  1 
ATOM   5965  C  CG  . ASP C 1 67  ? 295.553 272.208 260.217 1.00 67.25  ? 67  ASP C CG  1 
ATOM   5966  O  OD1 . ASP C 1 67  ? 296.600 271.547 260.380 1.00 64.70  ? 67  ASP C OD1 1 
ATOM   5967  O  OD2 . ASP C 1 67  ? 294.695 271.912 259.358 1.00 62.56  ? 67  ASP C OD2 1 
ATOM   5968  N  N   . SER C 1 68  ? 296.663 275.080 263.438 1.00 67.93  ? 68  SER C N   1 
ATOM   5969  C  CA  . SER C 1 68  ? 296.556 275.951 264.604 1.00 70.11  ? 68  SER C CA  1 
ATOM   5970  C  C   . SER C 1 68  ? 295.113 276.065 265.079 1.00 68.25  ? 68  SER C C   1 
ATOM   5971  O  O   . SER C 1 68  ? 294.846 276.663 266.126 1.00 72.42  ? 68  SER C O   1 
ATOM   5972  C  CB  . SER C 1 68  ? 297.124 277.338 264.301 1.00 73.08  ? 68  SER C CB  1 
ATOM   5973  O  OG  . SER C 1 68  ? 297.125 278.141 265.469 1.00 77.93  ? 68  SER C OG  1 
ATOM   5974  N  N   . LEU C 1 69  ? 294.176 275.493 264.323 1.00 61.38  ? 69  LEU C N   1 
ATOM   5975  C  CA  . LEU C 1 69  ? 292.816 275.296 264.799 1.00 51.66  ? 69  LEU C CA  1 
ATOM   5976  C  C   . LEU C 1 69  ? 292.492 273.837 265.064 1.00 46.97  ? 69  LEU C C   1 
ATOM   5977  O  O   . LEU C 1 69  ? 291.544 273.554 265.802 1.00 47.95  ? 69  LEU C O   1 
ATOM   5978  C  CB  . LEU C 1 69  ? 291.800 275.866 263.799 1.00 56.43  ? 69  LEU C CB  1 
ATOM   5979  C  CG  . LEU C 1 69  ? 291.460 277.344 264.003 1.00 58.69  ? 69  LEU C CG  1 
ATOM   5980  C  CD1 . LEU C 1 69  ? 290.395 277.805 263.020 1.00 51.78  ? 69  LEU C CD1 1 
ATOM   5981  C  CD2 . LEU C 1 69  ? 291.019 277.596 265.436 1.00 56.13  ? 69  LEU C CD2 1 
ATOM   5982  N  N   . TRP C 1 70  ? 293.255 272.913 264.481 1.00 46.44  ? 70  TRP C N   1 
ATOM   5983  C  CA  . TRP C 1 70  ? 293.146 271.497 264.789 1.00 39.97  ? 70  TRP C CA  1 
ATOM   5984  C  C   . TRP C 1 70  ? 293.978 271.101 265.999 1.00 44.21  ? 70  TRP C C   1 
ATOM   5985  O  O   . TRP C 1 70  ? 293.866 269.961 266.460 1.00 48.40  ? 70  TRP C O   1 
ATOM   5986  C  CB  . TRP C 1 70  ? 293.570 270.667 263.575 1.00 38.30  ? 70  TRP C CB  1 
ATOM   5987  C  CG  . TRP C 1 70  ? 292.473 270.443 262.580 1.00 37.28  ? 70  TRP C CG  1 
ATOM   5988  C  CD1 . TRP C 1 70  ? 292.174 271.221 261.503 1.00 36.03  ? 70  TRP C CD1 1 
ATOM   5989  C  CD2 . TRP C 1 70  ? 291.537 269.358 262.562 1.00 34.57  ? 70  TRP C CD2 1 
ATOM   5990  N  NE1 . TRP C 1 70  ? 291.108 270.695 260.818 1.00 35.55  ? 70  TRP C NE1 1 
ATOM   5991  C  CE2 . TRP C 1 70  ? 290.698 269.550 261.448 1.00 34.30  ? 70  TRP C CE2 1 
ATOM   5992  C  CE3 . TRP C 1 70  ? 291.327 268.246 263.381 1.00 31.23  ? 70  TRP C CE3 1 
ATOM   5993  C  CZ2 . TRP C 1 70  ? 289.665 268.672 261.132 1.00 28.36  ? 70  TRP C CZ2 1 
ATOM   5994  C  CZ3 . TRP C 1 70  ? 290.301 267.377 263.066 1.00 33.61  ? 70  TRP C CZ3 1 
ATOM   5995  C  CH2 . TRP C 1 70  ? 289.483 267.594 261.953 1.00 29.68  ? 70  TRP C CH2 1 
ATOM   5996  N  N   . GLY C 1 71  ? 294.807 272.004 266.512 1.00 41.87  ? 71  GLY C N   1 
ATOM   5997  C  CA  . GLY C 1 71  ? 295.603 271.716 267.694 1.00 41.58  ? 71  GLY C CA  1 
ATOM   5998  C  C   . GLY C 1 71  ? 296.540 270.541 267.527 1.00 46.46  ? 71  GLY C C   1 
ATOM   5999  O  O   . GLY C 1 71  ? 296.751 269.777 268.478 1.00 46.46  ? 71  GLY C O   1 
ATOM   6000  N  N   . ILE C 1 72  ? 297.111 270.379 266.340 1.00 48.50  ? 72  ILE C N   1 
ATOM   6001  C  CA  . ILE C 1 72  ? 297.984 269.257 266.025 1.00 50.79  ? 72  ILE C CA  1 
ATOM   6002  C  C   . ILE C 1 72  ? 299.329 269.811 265.570 1.00 55.43  ? 72  ILE C C   1 
ATOM   6003  O  O   . ILE C 1 72  ? 299.404 270.469 264.528 1.00 56.78  ? 72  ILE C O   1 
ATOM   6004  C  CB  . ILE C 1 72  ? 297.378 268.342 264.948 1.00 48.04  ? 72  ILE C CB  1 
ATOM   6005  C  CG1 . ILE C 1 72  ? 296.200 267.554 265.524 1.00 40.94  ? 72  ILE C CG1 1 
ATOM   6006  C  CG2 . ILE C 1 72  ? 298.432 267.403 264.392 1.00 48.67  ? 72  ILE C CG2 1 
ATOM   6007  C  CD1 . ILE C 1 72  ? 295.065 267.348 264.550 1.00 39.61  ? 72  ILE C CD1 1 
ATOM   6008  N  N   . PRO C 1 73  ? 300.412 269.577 266.308 1.00 56.10  ? 73  PRO C N   1 
ATOM   6009  C  CA  . PRO C 1 73  ? 301.717 270.097 265.884 1.00 53.61  ? 73  PRO C CA  1 
ATOM   6010  C  C   . PRO C 1 73  ? 302.161 269.485 264.564 1.00 54.53  ? 73  PRO C C   1 
ATOM   6011  O  O   . PRO C 1 73  ? 301.820 268.348 264.232 1.00 57.25  ? 73  PRO C O   1 
ATOM   6012  C  CB  . PRO C 1 73  ? 302.651 269.692 267.030 1.00 53.30  ? 73  PRO C CB  1 
ATOM   6013  C  CG  . PRO C 1 73  ? 301.962 268.549 267.698 1.00 53.00  ? 73  PRO C CG  1 
ATOM   6014  C  CD  . PRO C 1 73  ? 300.496 268.822 267.569 1.00 49.51  ? 73  PRO C CD  1 
ATOM   6015  N  N   . ALA C 1 74  ? 302.932 270.261 263.808 1.00 56.57  ? 74  ALA C N   1 
ATOM   6016  C  CA  . ALA C 1 74  ? 303.428 269.813 262.515 1.00 58.27  ? 74  ALA C CA  1 
ATOM   6017  C  C   . ALA C 1 74  ? 304.686 268.972 262.694 1.00 55.87  ? 74  ALA C C   1 
ATOM   6018  O  O   . ALA C 1 74  ? 305.632 269.387 263.372 1.00 52.19  ? 74  ALA C O   1 
ATOM   6019  C  CB  . ALA C 1 74  ? 303.714 271.009 261.610 1.00 61.08  ? 74  ALA C CB  1 
ATOM   6020  N  N   . GLU C 1 75  ? 304.693 267.790 262.085 1.00 55.84  ? 75  GLU C N   1 
ATOM   6021  C  CA  . GLU C 1 75  ? 305.829 266.881 262.122 1.00 53.99  ? 75  GLU C CA  1 
ATOM   6022  C  C   . GLU C 1 75  ? 306.294 266.608 260.699 1.00 48.03  ? 75  GLU C C   1 
ATOM   6023  O  O   . GLU C 1 75  ? 305.478 266.301 259.825 1.00 52.75  ? 75  GLU C O   1 
ATOM   6024  C  CB  . GLU C 1 75  ? 305.464 265.570 262.822 1.00 54.74  ? 75  GLU C CB  1 
ATOM   6025  C  CG  . GLU C 1 75  ? 306.406 265.180 263.949 1.00 63.25  ? 75  GLU C CG  1 
ATOM   6026  C  CD  . GLU C 1 75  ? 306.406 266.181 265.088 1.00 63.74  ? 75  GLU C CD  1 
ATOM   6027  O  OE1 . GLU C 1 75  ? 305.309 266.607 265.509 1.00 60.18  ? 75  GLU C OE1 1 
ATOM   6028  O  OE2 . GLU C 1 75  ? 307.503 266.538 265.567 1.00 60.35  ? 75  GLU C OE2 1 
ATOM   6029  N  N   . SER C 1 76  ? 307.600 266.721 260.471 1.00 42.62  ? 76  SER C N   1 
ATOM   6030  C  CA  . SER C 1 76  ? 308.170 266.507 259.150 1.00 38.97  ? 76  SER C CA  1 
ATOM   6031  C  C   . SER C 1 76  ? 309.485 265.753 259.277 1.00 36.11  ? 76  SER C C   1 
ATOM   6032  O  O   . SER C 1 76  ? 310.239 265.940 260.234 1.00 39.40  ? 76  SER C O   1 
ATOM   6033  C  CB  . SER C 1 76  ? 308.391 267.830 258.408 1.00 42.87  ? 76  SER C CB  1 
ATOM   6034  O  OG  . SER C 1 76  ? 309.622 268.423 258.779 1.00 50.86  ? 76  SER C OG  1 
ATOM   6035  N  N   . ARG C 1 77  ? 309.749 264.901 258.295 1.00 31.65  ? 77  ARG C N   1 
ATOM   6036  C  CA  . ARG C 1 77  ? 310.959 264.087 258.288 1.00 31.22  ? 77  ARG C CA  1 
ATOM   6037  C  C   . ARG C 1 77  ? 311.366 263.740 256.861 1.00 27.84  ? 77  ARG C C   1 
ATOM   6038  O  O   . ARG C 1 77  ? 310.577 263.147 256.120 1.00 26.70  ? 77  ARG C O   1 
ATOM   6039  C  CB  . ARG C 1 77  ? 310.748 262.812 259.105 1.00 28.24  ? 77  ARG C CB  1 
ATOM   6040  C  CG  . ARG C 1 77  ? 311.909 261.840 259.045 1.00 26.78  ? 77  ARG C CG  1 
ATOM   6041  C  CD  . ARG C 1 77  ? 312.432 261.519 260.430 1.00 25.61  ? 77  ARG C CD  1 
ATOM   6042  N  NE  . ARG C 1 77  ? 313.743 260.886 260.378 1.00 29.51  ? 77  ARG C NE  1 
ATOM   6043  C  CZ  . ARG C 1 77  ? 313.951 259.583 260.506 1.00 28.45  ? 77  ARG C CZ  1 
ATOM   6044  N  NH1 . ARG C 1 77  ? 312.951 258.740 260.699 1.00 27.86  ? 77  ARG C NH1 1 
ATOM   6045  N  NH2 . ARG C 1 77  ? 315.193 259.115 260.434 1.00 31.87  ? 77  ARG C NH2 1 
ATOM   6046  N  N   . PRO C 1 78  ? 312.569 264.109 256.429 1.00 24.98  ? 78  PRO C N   1 
ATOM   6047  C  CA  . PRO C 1 78  ? 313.022 263.707 255.092 1.00 21.87  ? 78  PRO C CA  1 
ATOM   6048  C  C   . PRO C 1 78  ? 313.452 262.248 255.064 1.00 22.27  ? 78  PRO C C   1 
ATOM   6049  O  O   . PRO C 1 78  ? 314.144 261.763 255.963 1.00 24.38  ? 78  PRO C O   1 
ATOM   6050  C  CB  . PRO C 1 78  ? 314.207 264.642 254.820 1.00 18.82  ? 78  PRO C CB  1 
ATOM   6051  C  CG  . PRO C 1 78  ? 314.674 265.076 256.157 1.00 19.45  ? 78  PRO C CG  1 
ATOM   6052  C  CD  . PRO C 1 78  ? 313.503 265.037 257.088 1.00 20.16  ? 78  PRO C CD  1 
ATOM   6053  N  N   . ILE C 1 79  ? 313.029 261.543 254.013 1.00 20.13  ? 79  ILE C N   1 
ATOM   6054  C  CA  . ILE C 1 79  ? 313.327 260.128 253.832 1.00 19.00  ? 79  ILE C CA  1 
ATOM   6055  C  C   . ILE C 1 79  ? 313.612 259.864 252.358 1.00 17.65  ? 79  ILE C C   1 
ATOM   6056  O  O   . ILE C 1 79  ? 313.354 260.699 251.489 1.00 18.55  ? 79  ILE C O   1 
ATOM   6057  C  CB  . ILE C 1 79  ? 312.183 259.215 254.328 1.00 20.35  ? 79  ILE C CB  1 
ATOM   6058  C  CG1 . ILE C 1 79  ? 310.918 259.426 253.492 1.00 19.49  ? 79  ILE C CG1 1 
ATOM   6059  C  CG2 . ILE C 1 79  ? 311.903 259.453 255.801 1.00 18.81  ? 79  ILE C CG2 1 
ATOM   6060  C  CD1 . ILE C 1 79  ? 310.717 258.391 252.410 1.00 15.71  ? 79  ILE C CD1 1 
ATOM   6061  N  N   . SER C 1 80  ? 314.157 258.678 252.091 1.00 17.96  ? 80  SER C N   1 
ATOM   6062  C  CA  . SER C 1 80  ? 314.472 258.222 250.745 1.00 14.67  ? 80  SER C CA  1 
ATOM   6063  C  C   . SER C 1 80  ? 313.926 256.816 250.549 1.00 17.67  ? 80  SER C C   1 
ATOM   6064  O  O   . SER C 1 80  ? 313.960 255.995 251.470 1.00 23.75  ? 80  SER C O   1 
ATOM   6065  C  CB  . SER C 1 80  ? 315.984 258.232 250.490 1.00 13.66  ? 80  SER C CB  1 
ATOM   6066  O  OG  . SER C 1 80  ? 316.434 259.524 250.136 1.00 18.89  ? 80  SER C OG  1 
ATOM   6067  N  N   . VAL C 1 81  ? 313.416 256.544 249.348 1.00 18.30  ? 81  VAL C N   1 
ATOM   6068  C  CA  . VAL C 1 81  ? 312.866 255.240 249.011 1.00 17.65  ? 81  VAL C CA  1 
ATOM   6069  C  C   . VAL C 1 81  ? 313.429 254.778 247.674 1.00 19.56  ? 81  VAL C C   1 
ATOM   6070  O  O   . VAL C 1 81  ? 313.864 255.576 246.840 1.00 23.61  ? 81  VAL C O   1 
ATOM   6071  C  CB  . VAL C 1 81  ? 311.322 255.247 248.960 1.00 17.82  ? 81  VAL C CB  1 
ATOM   6072  C  CG1 . VAL C 1 81  ? 310.744 255.304 250.363 1.00 18.28  ? 81  VAL C CG1 1 
ATOM   6073  C  CG2 . VAL C 1 81  ? 310.825 256.408 248.117 1.00 17.23  ? 81  VAL C CG2 1 
ATOM   6074  N  N   . ASP C 1 82  ? 313.408 253.463 247.482 1.00 18.38  ? 82  ASP C N   1 
ATOM   6075  C  CA  . ASP C 1 82  ? 313.816 252.838 246.236 1.00 20.22  ? 82  ASP C CA  1 
ATOM   6076  C  C   . ASP C 1 82  ? 312.621 252.713 245.292 1.00 20.04  ? 82  ASP C C   1 
ATOM   6077  O  O   . ASP C 1 82  ? 311.470 252.934 245.670 1.00 21.80  ? 82  ASP C O   1 
ATOM   6078  C  CB  . ASP C 1 82  ? 314.436 251.468 246.508 1.00 19.57  ? 82  ASP C CB  1 
ATOM   6079  C  CG  . ASP C 1 82  ? 315.699 251.232 245.708 1.00 30.32  ? 82  ASP C CG  1 
ATOM   6080  O  OD1 . ASP C 1 82  ? 315.799 251.758 244.581 1.00 26.75  ? 82  ASP C OD1 1 
ATOM   6081  O  OD2 . ASP C 1 82  ? 316.597 250.522 246.208 1.00 43.20  ? 82  ASP C OD2 1 
ATOM   6082  N  N   . ALA C 1 83  ? 312.909 252.349 244.047 1.00 19.03  ? 83  ALA C N   1 
ATOM   6083  C  CA  . ALA C 1 83  ? 311.867 252.241 243.037 1.00 19.00  ? 83  ALA C CA  1 
ATOM   6084  C  C   . ALA C 1 83  ? 310.953 251.054 243.324 1.00 21.53  ? 83  ALA C C   1 
ATOM   6085  O  O   . ALA C 1 83  ? 311.365 250.054 243.916 1.00 24.88  ? 83  ALA C O   1 
ATOM   6086  C  CB  . ALA C 1 83  ? 312.487 252.102 241.649 1.00 19.21  ? 83  ALA C CB  1 
ATOM   6087  N  N   . PHE C 1 84  ? 309.693 251.176 242.909 1.00 19.65  ? 84  PHE C N   1 
ATOM   6088  C  CA  . PHE C 1 84  ? 308.751 250.079 243.092 1.00 20.55  ? 84  PHE C CA  1 
ATOM   6089  C  C   . PHE C 1 84  ? 307.588 250.228 242.121 1.00 21.31  ? 84  PHE C C   1 
ATOM   6090  O  O   . PHE C 1 84  ? 307.307 251.316 241.621 1.00 24.31  ? 84  PHE C O   1 
ATOM   6091  C  CB  . PHE C 1 84  ? 308.240 250.011 244.538 1.00 20.24  ? 84  PHE C CB  1 
ATOM   6092  C  CG  . PHE C 1 84  ? 307.595 251.282 245.026 1.00 18.93  ? 84  PHE C CG  1 
ATOM   6093  C  CD1 . PHE C 1 84  ? 308.363 252.306 245.553 1.00 20.22  ? 84  PHE C CD1 1 
ATOM   6094  C  CD2 . PHE C 1 84  ? 306.222 251.445 244.971 1.00 19.80  ? 84  PHE C CD2 1 
ATOM   6095  C  CE1 . PHE C 1 84  ? 307.775 253.471 246.008 1.00 18.19  ? 84  PHE C CE1 1 
ATOM   6096  C  CE2 . PHE C 1 84  ? 305.628 252.609 245.423 1.00 15.49  ? 84  PHE C CE2 1 
ATOM   6097  C  CZ  . PHE C 1 84  ? 306.406 253.622 245.943 1.00 17.23  ? 84  PHE C CZ  1 
ATOM   6098  N  N   . TRP C 1 85  ? 306.908 249.115 241.871 1.00 21.74  ? 85  TRP C N   1 
ATOM   6099  C  CA  . TRP C 1 85  ? 305.675 249.116 241.100 1.00 20.27  ? 85  TRP C CA  1 
ATOM   6100  C  C   . TRP C 1 85  ? 304.503 249.402 242.026 1.00 19.57  ? 85  TRP C C   1 
ATOM   6101  O  O   . TRP C 1 85  ? 304.413 248.837 243.118 1.00 22.28  ? 85  TRP C O   1 
ATOM   6102  C  CB  . TRP C 1 85  ? 305.467 247.768 240.412 1.00 25.01  ? 85  TRP C CB  1 
ATOM   6103  C  CG  . TRP C 1 85  ? 306.546 247.391 239.456 1.00 30.52  ? 85  TRP C CG  1 
ATOM   6104  C  CD1 . TRP C 1 85  ? 307.602 246.567 239.702 1.00 31.14  ? 85  TRP C CD1 1 
ATOM   6105  C  CD2 . TRP C 1 85  ? 306.666 247.801 238.090 1.00 34.02  ? 85  TRP C CD2 1 
ATOM   6106  N  NE1 . TRP C 1 85  ? 308.380 246.448 238.579 1.00 35.76  ? 85  TRP C NE1 1 
ATOM   6107  C  CE2 . TRP C 1 85  ? 307.826 247.193 237.574 1.00 36.47  ? 85  TRP C CE2 1 
ATOM   6108  C  CE3 . TRP C 1 85  ? 305.906 248.624 237.254 1.00 33.61  ? 85  TRP C CE3 1 
ATOM   6109  C  CZ2 . TRP C 1 85  ? 308.247 247.385 236.263 1.00 38.97  ? 85  TRP C CZ2 1 
ATOM   6110  C  CZ3 . TRP C 1 85  ? 306.325 248.813 235.954 1.00 36.34  ? 85  TRP C CZ3 1 
ATOM   6111  C  CH2 . TRP C 1 85  ? 307.485 248.197 235.470 1.00 37.65  ? 85  TRP C CH2 1 
ATOM   6112  N  N   . MET C 1 86  ? 303.602 250.274 241.581 1.00 19.41  ? 86  MET C N   1 
ATOM   6113  C  CA  . MET C 1 86  ? 302.404 250.621 242.332 1.00 16.66  ? 86  MET C CA  1 
ATOM   6114  C  C   . MET C 1 86  ? 301.181 250.473 241.443 1.00 17.74  ? 86  MET C C   1 
ATOM   6115  O  O   . MET C 1 86  ? 301.212 250.843 240.267 1.00 23.39  ? 86  MET C O   1 
ATOM   6116  C  CB  . MET C 1 86  ? 302.470 252.051 242.877 1.00 17.61  ? 86  MET C CB  1 
ATOM   6117  C  CG  . MET C 1 86  ? 301.471 252.326 243.987 1.00 14.75  ? 86  MET C CG  1 
ATOM   6118  S  SD  . MET C 1 86  ? 301.605 253.982 244.671 1.00 38.62  ? 86  MET C SD  1 
ATOM   6119  C  CE  . MET C 1 86  ? 301.600 253.622 246.422 1.00 14.62  ? 86  MET C CE  1 
ATOM   6120  N  N   . ASP C 1 87  ? 300.101 249.946 242.013 1.00 19.75  ? 87  ASP C N   1 
ATOM   6121  C  CA  . ASP C 1 87  ? 298.862 249.802 241.262 1.00 19.30  ? 87  ASP C CA  1 
ATOM   6122  C  C   . ASP C 1 87  ? 298.382 251.155 240.758 1.00 21.65  ? 87  ASP C C   1 
ATOM   6123  O  O   . ASP C 1 87  ? 298.401 252.153 241.483 1.00 24.03  ? 87  ASP C O   1 
ATOM   6124  C  CB  . ASP C 1 87  ? 297.782 249.152 242.127 1.00 18.89  ? 87  ASP C CB  1 
ATOM   6125  C  CG  . ASP C 1 87  ? 297.709 247.655 241.938 1.00 27.39  ? 87  ASP C CG  1 
ATOM   6126  O  OD1 . ASP C 1 87  ? 297.868 247.192 240.790 1.00 32.28  ? 87  ASP C OD1 1 
ATOM   6127  O  OD2 . ASP C 1 87  ? 297.489 246.938 242.934 1.00 25.83  ? 87  ASP C OD2 1 
ATOM   6128  N  N   . ARG C 1 88  ? 297.940 251.180 239.499 1.00 22.32  ? 88  ARG C N   1 
ATOM   6129  C  CA  . ARG C 1 88  ? 297.467 252.425 238.906 1.00 21.28  ? 88  ARG C CA  1 
ATOM   6130  C  C   . ARG C 1 88  ? 296.249 252.962 239.647 1.00 20.49  ? 88  ARG C C   1 
ATOM   6131  O  O   . ARG C 1 88  ? 296.146 254.168 239.895 1.00 21.07  ? 88  ARG C O   1 
ATOM   6132  C  CB  . ARG C 1 88  ? 297.143 252.210 237.429 1.00 26.80  ? 88  ARG C CB  1 
ATOM   6133  C  CG  . ARG C 1 88  ? 297.391 253.421 236.555 1.00 33.39  ? 88  ARG C CG  1 
ATOM   6134  C  CD  . ARG C 1 88  ? 297.285 253.055 235.089 1.00 39.86  ? 88  ARG C CD  1 
ATOM   6135  N  NE  . ARG C 1 88  ? 298.476 252.357 234.623 1.00 46.41  ? 88  ARG C NE  1 
ATOM   6136  C  CZ  . ARG C 1 88  ? 298.463 251.165 234.043 1.00 49.15  ? 88  ARG C CZ  1 
ATOM   6137  N  NH1 . ARG C 1 88  ? 297.333 250.505 233.846 1.00 49.13  ? 88  ARG C NH1 1 
ATOM   6138  N  NH2 . ARG C 1 88  ? 299.612 250.620 233.654 1.00 43.68  ? 88  ARG C NH2 1 
ATOM   6139  N  N   . THR C 1 89  ? 295.315 252.084 240.001 1.00 19.10  ? 89  THR C N   1 
ATOM   6140  C  CA  . THR C 1 89  ? 294.105 252.463 240.713 1.00 16.70  ? 89  THR C CA  1 
ATOM   6141  C  C   . THR C 1 89  ? 293.949 251.599 241.956 1.00 18.38  ? 89  THR C C   1 
ATOM   6142  O  O   . THR C 1 89  ? 294.673 250.622 242.161 1.00 22.98  ? 89  THR C O   1 
ATOM   6143  C  CB  . THR C 1 89  ? 292.860 252.330 239.822 1.00 20.13  ? 89  THR C CB  1 
ATOM   6144  O  OG1 . THR C 1 89  ? 292.425 250.966 239.803 1.00 26.96  ? 89  THR C OG1 1 
ATOM   6145  C  CG2 . THR C 1 89  ? 293.167 252.776 238.405 1.00 22.43  ? 89  THR C CG2 1 
ATOM   6146  N  N   . GLU C 1 90  ? 292.991 251.978 242.795 1.00 18.69  ? 90  GLU C N   1 
ATOM   6147  C  CA  . GLU C 1 90  ? 292.628 251.158 243.939 1.00 16.17  ? 90  GLU C CA  1 
ATOM   6148  C  C   . GLU C 1 90  ? 291.982 249.857 243.473 1.00 19.92  ? 90  GLU C C   1 
ATOM   6149  O  O   . GLU C 1 90  ? 291.369 249.790 242.404 1.00 24.43  ? 90  GLU C O   1 
ATOM   6150  C  CB  . GLU C 1 90  ? 291.675 251.922 244.858 1.00 15.12  ? 90  GLU C CB  1 
ATOM   6151  C  CG  . GLU C 1 90  ? 292.081 253.367 245.107 1.00 20.58  ? 90  GLU C CG  1 
ATOM   6152  C  CD  . GLU C 1 90  ? 290.895 254.307 245.198 1.00 21.53  ? 90  GLU C CD  1 
ATOM   6153  O  OE1 . GLU C 1 90  ? 289.928 254.126 244.432 1.00 25.95  ? 90  GLU C OE1 1 
ATOM   6154  O  OE2 . GLU C 1 90  ? 290.931 255.232 246.033 1.00 19.61  ? 90  GLU C OE2 1 
ATOM   6155  N  N   . ILE C 1 91  ? 292.134 248.810 244.287 1.00 19.35  ? 91  ILE C N   1 
ATOM   6156  C  CA  . ILE C 1 91  ? 291.544 247.518 243.956 1.00 17.78  ? 91  ILE C CA  1 
ATOM   6157  C  C   . ILE C 1 91  ? 290.035 247.668 243.822 1.00 17.00  ? 91  ILE C C   1 
ATOM   6158  O  O   . ILE C 1 91  ? 289.372 248.255 244.686 1.00 19.83  ? 91  ILE C O   1 
ATOM   6159  C  CB  . ILE C 1 91  ? 291.915 246.473 245.020 1.00 18.43  ? 91  ILE C CB  1 
ATOM   6160  C  CG1 . ILE C 1 91  ? 293.436 246.356 245.150 1.00 16.82  ? 91  ILE C CG1 1 
ATOM   6161  C  CG2 . ILE C 1 91  ? 291.308 245.123 244.683 1.00 17.20  ? 91  ILE C CG2 1 
ATOM   6162  C  CD1 . ILE C 1 91  ? 294.114 245.792 243.925 1.00 17.93  ? 91  ILE C CD1 1 
ATOM   6163  N  N   . THR C 1 92  ? 289.484 247.128 242.739 1.00 18.58  ? 92  THR C N   1 
ATOM   6164  C  CA  . THR C 1 92  ? 288.066 247.245 242.435 1.00 18.64  ? 92  THR C CA  1 
ATOM   6165  C  C   . THR C 1 92  ? 287.292 246.037 242.957 1.00 19.15  ? 92  THR C C   1 
ATOM   6166  O  O   . THR C 1 92  ? 287.860 245.066 243.461 1.00 19.60  ? 92  THR C O   1 
ATOM   6167  C  CB  . THR C 1 92  ? 287.843 247.403 240.926 1.00 17.82  ? 92  THR C CB  1 
ATOM   6168  O  OG1 . THR C 1 92  ? 288.249 246.208 240.249 1.00 20.85  ? 92  THR C OG1 1 
ATOM   6169  C  CG2 . THR C 1 92  ? 288.630 248.584 240.384 1.00 14.75  ? 92  THR C CG2 1 
ATOM   6170  N  N   . ASN C 1 93  ? 285.965 246.119 242.831 1.00 19.96  ? 93  ASN C N   1 
ATOM   6171  C  CA  . ASN C 1 93  ? 285.102 245.030 243.278 1.00 18.54  ? 93  ASN C CA  1 
ATOM   6172  C  C   . ASN C 1 93  ? 285.353 243.753 242.485 1.00 21.46  ? 93  ASN C C   1 
ATOM   6173  O  O   . ASN C 1 93  ? 285.344 242.654 243.048 1.00 24.67  ? 93  ASN C O   1 
ATOM   6174  C  CB  . ASN C 1 93  ? 283.633 245.443 243.171 1.00 20.46  ? 93  ASN C CB  1 
ATOM   6175  C  CG  . ASN C 1 93  ? 283.196 246.352 244.303 1.00 21.26  ? 93  ASN C CG  1 
ATOM   6176  O  OD1 . ASN C 1 93  ? 283.353 246.019 245.476 1.00 22.57  ? 93  ASN C OD1 1 
ATOM   6177  N  ND2 . ASN C 1 93  ? 282.634 247.502 243.956 1.00 20.03  ? 93  ASN C ND2 1 
ATOM   6178  N  N   . ALA C 1 94  ? 285.566 243.875 241.173 1.00 19.18  ? 94  ALA C N   1 
ATOM   6179  C  CA  . ALA C 1 94  ? 285.803 242.692 240.349 1.00 23.07  ? 94  ALA C CA  1 
ATOM   6180  C  C   . ALA C 1 94  ? 287.158 242.062 240.652 1.00 27.25  ? 94  ALA C C   1 
ATOM   6181  O  O   . ALA C 1 94  ? 287.292 240.830 240.668 1.00 33.13  ? 94  ALA C O   1 
ATOM   6182  C  CB  . ALA C 1 94  ? 285.697 243.058 238.870 1.00 22.01  ? 94  ALA C CB  1 
ATOM   6183  N  N   . GLN C 1 95  ? 288.175 242.889 240.896 1.00 22.62  ? 95  GLN C N   1 
ATOM   6184  C  CA  . GLN C 1 95  ? 289.503 242.359 241.185 1.00 22.36  ? 95  GLN C CA  1 
ATOM   6185  C  C   . GLN C 1 95  ? 289.505 241.546 242.472 1.00 20.77  ? 95  GLN C C   1 
ATOM   6186  O  O   . GLN C 1 95  ? 290.153 240.496 242.551 1.00 27.89  ? 95  GLN C O   1 
ATOM   6187  C  CB  . GLN C 1 95  ? 290.513 243.502 241.260 1.00 25.08  ? 95  GLN C CB  1 
ATOM   6188  C  CG  . GLN C 1 95  ? 291.015 243.959 239.901 1.00 24.49  ? 95  GLN C CG  1 
ATOM   6189  C  CD  . GLN C 1 95  ? 291.407 245.418 239.882 1.00 22.44  ? 95  GLN C CD  1 
ATOM   6190  O  OE1 . GLN C 1 95  ? 291.312 246.112 240.891 1.00 23.81  ? 95  GLN C OE1 1 
ATOM   6191  N  NE2 . GLN C 1 95  ? 291.854 245.894 238.727 1.00 19.57  ? 95  GLN C NE2 1 
ATOM   6192  N  N   . TYR C 1 96  ? 288.797 242.020 243.498 1.00 19.72  ? 96  TYR C N   1 
ATOM   6193  C  CA  . TYR C 1 96  ? 288.684 241.253 244.734 1.00 18.74  ? 96  TYR C CA  1 
ATOM   6194  C  C   . TYR C 1 96  ? 287.740 240.067 244.570 1.00 21.96  ? 96  TYR C C   1 
ATOM   6195  O  O   . TYR C 1 96  ? 287.930 239.024 245.211 1.00 25.98  ? 96  TYR C O   1 
ATOM   6196  C  CB  . TYR C 1 96  ? 288.218 242.164 245.867 1.00 16.53  ? 96  TYR C CB  1 
ATOM   6197  C  CG  . TYR C 1 96  ? 288.502 241.617 247.243 1.00 17.46  ? 96  TYR C CG  1 
ATOM   6198  C  CD1 . TYR C 1 96  ? 289.716 241.862 247.870 1.00 16.02  ? 96  TYR C CD1 1 
ATOM   6199  C  CD2 . TYR C 1 96  ? 287.557 240.859 247.918 1.00 15.37  ? 96  TYR C CD2 1 
ATOM   6200  C  CE1 . TYR C 1 96  ? 289.982 241.363 249.127 1.00 15.62  ? 96  TYR C CE1 1 
ATOM   6201  C  CE2 . TYR C 1 96  ? 287.815 240.355 249.175 1.00 14.51  ? 96  TYR C CE2 1 
ATOM   6202  C  CZ  . TYR C 1 96  ? 289.028 240.611 249.775 1.00 16.47  ? 96  TYR C CZ  1 
ATOM   6203  O  OH  . TYR C 1 96  ? 289.285 240.111 251.028 1.00 22.19  ? 96  TYR C OH  1 
ATOM   6204  N  N   . ARG C 1 97  ? 286.717 240.209 243.726 1.00 22.48  ? 97  ARG C N   1 
ATOM   6205  C  CA  . ARG C 1 97  ? 285.839 239.084 243.438 1.00 22.97  ? 97  ARG C CA  1 
ATOM   6206  C  C   . ARG C 1 97  ? 286.603 237.941 242.791 1.00 24.81  ? 97  ARG C C   1 
ATOM   6207  O  O   . ARG C 1 97  ? 286.231 236.778 242.953 1.00 26.68  ? 97  ARG C O   1 
ATOM   6208  C  CB  . ARG C 1 97  ? 284.685 239.531 242.542 1.00 24.05  ? 97  ARG C CB  1 
ATOM   6209  C  CG  . ARG C 1 97  ? 283.384 238.794 242.797 1.00 22.62  ? 97  ARG C CG  1 
ATOM   6210  C  CD  . ARG C 1 97  ? 282.275 239.304 241.898 1.00 29.73  ? 97  ARG C CD  1 
ATOM   6211  N  NE  . ARG C 1 97  ? 281.749 240.586 242.351 1.00 26.71  ? 97  ARG C NE  1 
ATOM   6212  C  CZ  . ARG C 1 97  ? 281.825 241.712 241.657 1.00 27.53  ? 97  ARG C CZ  1 
ATOM   6213  N  NH1 . ARG C 1 97  ? 282.404 241.755 240.470 1.00 26.27  ? 97  ARG C NH1 1 
ATOM   6214  N  NH2 . ARG C 1 97  ? 281.305 242.824 242.167 1.00 30.78  ? 97  ARG C NH2 1 
ATOM   6215  N  N   . GLN C 1 98  ? 287.669 238.250 242.052 1.00 24.61  ? 98  GLN C N   1 
ATOM   6216  C  CA  . GLN C 1 98  ? 288.510 237.182 241.513 1.00 26.58  ? 98  GLN C CA  1 
ATOM   6217  C  C   . GLN C 1 98  ? 289.137 236.355 242.632 1.00 23.84  ? 98  GLN C C   1 
ATOM   6218  O  O   . GLN C 1 98  ? 289.157 235.119 242.570 1.00 26.36  ? 98  GLN C O   1 
ATOM   6219  C  CB  . GLN C 1 98  ? 289.590 237.769 240.607 1.00 27.42  ? 98  GLN C CB  1 
ATOM   6220  C  CG  . GLN C 1 98  ? 289.992 236.849 239.476 1.00 31.61  ? 98  GLN C CG  1 
ATOM   6221  C  CD  . GLN C 1 98  ? 291.312 237.238 238.853 1.00 43.93  ? 98  GLN C CD  1 
ATOM   6222  O  OE1 . GLN C 1 98  ? 291.558 238.409 238.578 1.00 50.73  ? 98  GLN C OE1 1 
ATOM   6223  N  NE2 . GLN C 1 98  ? 292.176 236.255 238.638 1.00 49.18  ? 98  GLN C NE2 1 
ATOM   6224  N  N   . PHE C 1 99  ? 289.649 237.021 243.669 1.00 22.32  ? 99  PHE C N   1 
ATOM   6225  C  CA  . PHE C 1 99  ? 290.190 236.317 244.829 1.00 19.12  ? 99  PHE C CA  1 
ATOM   6226  C  C   . PHE C 1 99  ? 289.110 235.502 245.533 1.00 20.70  ? 99  PHE C C   1 
ATOM   6227  O  O   . PHE C 1 99  ? 289.333 234.343 245.915 1.00 25.07  ? 99  PHE C O   1 
ATOM   6228  C  CB  . PHE C 1 99  ? 290.814 237.339 245.780 1.00 17.28  ? 99  PHE C CB  1 
ATOM   6229  C  CG  . PHE C 1 99  ? 291.340 236.757 247.056 1.00 18.59  ? 99  PHE C CG  1 
ATOM   6230  C  CD1 . PHE C 1 99  ? 291.972 235.529 247.071 1.00 18.14  ? 99  PHE C CD1 1 
ATOM   6231  C  CD2 . PHE C 1 99  ? 291.216 237.455 248.244 1.00 14.44  ? 99  PHE C CD2 1 
ATOM   6232  C  CE1 . PHE C 1 99  ? 292.461 235.005 248.247 1.00 15.94  ? 99  PHE C CE1 1 
ATOM   6233  C  CE2 . PHE C 1 99  ? 291.703 236.936 249.422 1.00 14.54  ? 99  PHE C CE2 1 
ATOM   6234  C  CZ  . PHE C 1 99  ? 292.329 235.710 249.423 1.00 15.31  ? 99  PHE C CZ  1 
ATOM   6235  N  N   . VAL C 1 100 ? 287.930 236.097 245.710 1.00 18.54  ? 100 VAL C N   1 
ATOM   6236  C  CA  . VAL C 1 100 ? 286.833 235.392 246.370 1.00 21.33  ? 100 VAL C CA  1 
ATOM   6237  C  C   . VAL C 1 100 ? 286.450 234.144 245.583 1.00 24.68  ? 100 VAL C C   1 
ATOM   6238  O  O   . VAL C 1 100 ? 286.210 233.073 246.158 1.00 26.28  ? 100 VAL C O   1 
ATOM   6239  C  CB  . VAL C 1 100 ? 285.631 236.337 246.560 1.00 20.56  ? 100 VAL C CB  1 
ATOM   6240  C  CG1 . VAL C 1 100 ? 284.432 235.571 247.089 1.00 22.67  ? 100 VAL C CG1 1 
ATOM   6241  C  CG2 . VAL C 1 100 ? 285.998 237.475 247.497 1.00 20.63  ? 100 VAL C CG2 1 
ATOM   6242  N  N   . TYR C 1 101 ? 286.388 234.261 244.256 1.00 25.94  ? 101 TYR C N   1 
ATOM   6243  C  CA  . TYR C 1 101 ? 286.014 233.130 243.418 1.00 21.58  ? 101 TYR C CA  1 
ATOM   6244  C  C   . TYR C 1 101 ? 287.090 232.055 243.426 1.00 24.49  ? 101 TYR C C   1 
ATOM   6245  O  O   . TYR C 1 101 ? 286.776 230.861 243.384 1.00 31.29  ? 101 TYR C O   1 
ATOM   6246  C  CB  . TYR C 1 101 ? 285.738 233.604 241.994 1.00 24.26  ? 101 TYR C CB  1 
ATOM   6247  C  CG  . TYR C 1 101 ? 284.393 234.268 241.823 1.00 28.32  ? 101 TYR C CG  1 
ATOM   6248  C  CD1 . TYR C 1 101 ? 283.528 234.419 242.899 1.00 28.22  ? 101 TYR C CD1 1 
ATOM   6249  C  CD2 . TYR C 1 101 ? 283.988 234.744 240.587 1.00 26.90  ? 101 TYR C CD2 1 
ATOM   6250  C  CE1 . TYR C 1 101 ? 282.300 235.024 242.745 1.00 26.91  ? 101 TYR C CE1 1 
ATOM   6251  C  CE2 . TYR C 1 101 ? 282.761 235.352 240.424 1.00 25.36  ? 101 TYR C CE2 1 
ATOM   6252  C  CZ  . TYR C 1 101 ? 281.920 235.489 241.505 1.00 26.47  ? 101 TYR C CZ  1 
ATOM   6253  O  OH  . TYR C 1 101 ? 280.695 236.093 241.348 1.00 37.37  ? 101 TYR C OH  1 
ATOM   6254  N  N   . TYR C 1 102 ? 288.365 232.449 243.474 1.00 25.81  ? 102 TYR C N   1 
ATOM   6255  C  CA  . TYR C 1 102 ? 289.418 231.448 243.614 1.00 24.11  ? 102 TYR C CA  1 
ATOM   6256  C  C   . TYR C 1 102 ? 289.252 230.664 244.907 1.00 21.14  ? 102 TYR C C   1 
ATOM   6257  O  O   . TYR C 1 102 ? 289.345 229.431 244.916 1.00 25.57  ? 102 TYR C O   1 
ATOM   6258  C  CB  . TYR C 1 102 ? 290.800 232.096 243.568 1.00 20.88  ? 102 TYR C CB  1 
ATOM   6259  C  CG  . TYR C 1 102 ? 291.893 231.117 243.933 1.00 23.96  ? 102 TYR C CG  1 
ATOM   6260  C  CD1 . TYR C 1 102 ? 292.453 230.281 242.978 1.00 23.28  ? 102 TYR C CD1 1 
ATOM   6261  C  CD2 . TYR C 1 102 ? 292.341 231.006 245.243 1.00 24.76  ? 102 TYR C CD2 1 
ATOM   6262  C  CE1 . TYR C 1 102 ? 293.440 229.377 243.314 1.00 24.73  ? 102 TYR C CE1 1 
ATOM   6263  C  CE2 . TYR C 1 102 ? 293.325 230.105 245.588 1.00 25.19  ? 102 TYR C CE2 1 
ATOM   6264  C  CZ  . TYR C 1 102 ? 293.872 229.293 244.621 1.00 30.80  ? 102 TYR C CZ  1 
ATOM   6265  O  OH  . TYR C 1 102 ? 294.855 228.395 244.965 1.00 38.91  ? 102 TYR C OH  1 
ATOM   6266  N  N   . VAL C 1 103 ? 289.027 231.368 246.018 1.00 22.55  ? 103 VAL C N   1 
ATOM   6267  C  CA  . VAL C 1 103 ? 288.852 230.675 247.293 1.00 22.69  ? 103 VAL C CA  1 
ATOM   6268  C  C   . VAL C 1 103 ? 287.658 229.731 247.223 1.00 26.91  ? 103 VAL C C   1 
ATOM   6269  O  O   . VAL C 1 103 ? 287.726 228.577 247.672 1.00 29.46  ? 103 VAL C O   1 
ATOM   6270  C  CB  . VAL C 1 103 ? 288.707 231.691 248.441 1.00 22.74  ? 103 VAL C CB  1 
ATOM   6271  C  CG1 . VAL C 1 103 ? 288.197 231.005 249.696 1.00 21.98  ? 103 VAL C CG1 1 
ATOM   6272  C  CG2 . VAL C 1 103 ? 290.033 232.381 248.709 1.00 20.64  ? 103 VAL C CG2 1 
ATOM   6273  N  N   . ARG C 1 104 ? 286.547 230.206 246.655 1.00 26.48  ? 104 ARG C N   1 
ATOM   6274  C  CA  . ARG C 1 104 ? 285.352 229.376 246.539 1.00 22.79  ? 104 ARG C CA  1 
ATOM   6275  C  C   . ARG C 1 104 ? 285.627 228.122 245.718 1.00 27.63  ? 104 ARG C C   1 
ATOM   6276  O  O   . ARG C 1 104 ? 285.251 227.012 246.112 1.00 34.21  ? 104 ARG C O   1 
ATOM   6277  C  CB  . ARG C 1 104 ? 284.217 230.187 245.917 1.00 21.43  ? 104 ARG C CB  1 
ATOM   6278  C  CG  . ARG C 1 104 ? 283.016 229.358 245.506 1.00 25.44  ? 104 ARG C CG  1 
ATOM   6279  C  CD  . ARG C 1 104 ? 282.247 230.023 244.380 1.00 28.51  ? 104 ARG C CD  1 
ATOM   6280  N  NE  . ARG C 1 104 ? 282.977 229.982 243.120 1.00 29.79  ? 104 ARG C NE  1 
ATOM   6281  C  CZ  . ARG C 1 104 ? 282.699 230.739 242.069 1.00 29.24  ? 104 ARG C CZ  1 
ATOM   6282  N  NH1 . ARG C 1 104 ? 281.707 231.613 242.090 1.00 28.27  ? 104 ARG C NH1 1 
ATOM   6283  N  NH2 . ARG C 1 104 ? 283.434 230.616 240.968 1.00 28.60  ? 104 ARG C NH2 1 
ATOM   6284  N  N   . ASP C 1 105 ? 286.277 228.282 244.563 1.00 27.07  ? 105 ASP C N   1 
ATOM   6285  C  CA  . ASP C 1 105 ? 286.540 227.141 243.693 1.00 26.59  ? 105 ASP C CA  1 
ATOM   6286  C  C   . ASP C 1 105 ? 287.485 226.147 244.354 1.00 27.48  ? 105 ASP C C   1 
ATOM   6287  O  O   . ASP C 1 105 ? 287.289 224.931 244.250 1.00 34.55  ? 105 ASP C O   1 
ATOM   6288  C  CB  . ASP C 1 105 ? 287.112 227.622 242.360 1.00 30.34  ? 105 ASP C CB  1 
ATOM   6289  C  CG  . ASP C 1 105 ? 286.102 228.398 241.539 1.00 40.56  ? 105 ASP C CG  1 
ATOM   6290  O  OD1 . ASP C 1 105 ? 284.897 228.337 241.862 1.00 42.39  ? 105 ASP C OD1 1 
ATOM   6291  O  OD2 . ASP C 1 105 ? 286.511 229.071 240.571 1.00 43.61  ? 105 ASP C OD2 1 
ATOM   6292  N  N   . SER C 1 106 ? 288.522 226.642 245.032 1.00 27.26  ? 106 SER C N   1 
ATOM   6293  C  CA  . SER C 1 106 ? 289.450 225.742 245.708 1.00 31.16  ? 106 SER C CA  1 
ATOM   6294  C  C   . SER C 1 106 ? 288.752 224.953 246.808 1.00 31.86  ? 106 SER C C   1 
ATOM   6295  O  O   . SER C 1 106 ? 288.974 223.745 246.951 1.00 34.33  ? 106 SER C O   1 
ATOM   6296  C  CB  . SER C 1 106 ? 290.627 226.524 246.288 1.00 30.97  ? 106 SER C CB  1 
ATOM   6297  O  OG  . SER C 1 106 ? 291.059 225.911 247.488 1.00 37.26  ? 106 SER C OG  1 
ATOM   6298  N  N   . ILE C 1 107 ? 287.909 225.616 247.602 1.00 29.92  ? 107 ILE C N   1 
ATOM   6299  C  CA  . ILE C 1 107 ? 287.203 224.900 248.661 1.00 34.11  ? 107 ILE C CA  1 
ATOM   6300  C  C   . ILE C 1 107 ? 286.235 223.883 248.066 1.00 36.12  ? 107 ILE C C   1 
ATOM   6301  O  O   . ILE C 1 107 ? 286.103 222.759 248.570 1.00 40.07  ? 107 ILE C O   1 
ATOM   6302  C  CB  . ILE C 1 107 ? 286.493 225.893 249.598 1.00 34.39  ? 107 ILE C CB  1 
ATOM   6303  C  CG1 . ILE C 1 107 ? 287.512 226.566 250.518 1.00 33.77  ? 107 ILE C CG1 1 
ATOM   6304  C  CG2 . ILE C 1 107 ? 285.438 225.181 250.422 1.00 30.66  ? 107 ILE C CG2 1 
ATOM   6305  C  CD1 . ILE C 1 107 ? 287.012 227.832 251.168 1.00 30.77  ? 107 ILE C CD1 1 
ATOM   6306  N  N   . ILE C 1 108 ? 285.548 224.252 246.982 1.00 32.77  ? 108 ILE C N   1 
ATOM   6307  C  CA  . ILE C 1 108 ? 284.620 223.323 246.344 1.00 33.20  ? 108 ILE C CA  1 
ATOM   6308  C  C   . ILE C 1 108 ? 285.361 222.096 245.831 1.00 33.67  ? 108 ILE C C   1 
ATOM   6309  O  O   . ILE C 1 108 ? 284.889 220.964 245.976 1.00 38.00  ? 108 ILE C O   1 
ATOM   6310  C  CB  . ILE C 1 108 ? 283.841 224.027 245.218 1.00 35.13  ? 108 ILE C CB  1 
ATOM   6311  C  CG1 . ILE C 1 108 ? 282.711 224.873 245.803 1.00 31.76  ? 108 ILE C CG1 1 
ATOM   6312  C  CG2 . ILE C 1 108 ? 283.284 223.008 244.239 1.00 36.81  ? 108 ILE C CG2 1 
ATOM   6313  C  CD1 . ILE C 1 108 ? 282.043 225.775 244.795 1.00 28.82  ? 108 ILE C CD1 1 
ATOM   6314  N  N   . ARG C 1 109 ? 286.526 222.299 245.211 1.00 36.11  ? 109 ARG C N   1 
ATOM   6315  C  CA  . ARG C 1 109 ? 287.307 221.165 244.726 1.00 36.01  ? 109 ARG C CA  1 
ATOM   6316  C  C   . ARG C 1 109 ? 287.810 220.302 245.876 1.00 38.92  ? 109 ARG C C   1 
ATOM   6317  O  O   . ARG C 1 109 ? 287.816 219.070 245.778 1.00 41.53  ? 109 ARG C O   1 
ATOM   6318  C  CB  . ARG C 1 109 ? 288.473 221.655 243.870 1.00 33.46  ? 109 ARG C CB  1 
ATOM   6319  C  CG  . ARG C 1 109 ? 288.039 222.345 242.595 1.00 32.33  ? 109 ARG C CG  1 
ATOM   6320  C  CD  . ARG C 1 109 ? 289.159 223.174 242.000 1.00 38.92  ? 109 ARG C CD  1 
ATOM   6321  N  NE  . ARG C 1 109 ? 288.815 223.657 240.669 1.00 42.48  ? 109 ARG C NE  1 
ATOM   6322  C  CZ  . ARG C 1 109 ? 288.707 222.886 239.597 1.00 47.64  ? 109 ARG C CZ  1 
ATOM   6323  N  NH1 . ARG C 1 109 ? 288.921 221.583 239.658 1.00 50.78  ? 109 ARG C NH1 1 
ATOM   6324  N  NH2 . ARG C 1 109 ? 288.374 223.436 238.433 1.00 50.03  ? 109 ARG C NH2 1 
ATOM   6325  N  N   . GLU C 1 110 ? 288.241 220.926 246.974 1.00 39.26  ? 110 GLU C N   1 
ATOM   6326  C  CA  . GLU C 1 110 ? 288.666 220.148 248.132 1.00 39.41  ? 110 GLU C CA  1 
ATOM   6327  C  C   . GLU C 1 110 ? 287.527 219.289 248.661 1.00 42.31  ? 110 GLU C C   1 
ATOM   6328  O  O   . GLU C 1 110 ? 287.746 218.153 249.097 1.00 45.51  ? 110 GLU C O   1 
ATOM   6329  C  CB  . GLU C 1 110 ? 289.197 221.071 249.228 1.00 37.75  ? 110 GLU C CB  1 
ATOM   6330  C  CG  . GLU C 1 110 ? 290.657 221.446 249.066 1.00 45.28  ? 110 GLU C CG  1 
ATOM   6331  C  CD  . GLU C 1 110 ? 291.587 220.452 249.734 1.00 51.91  ? 110 GLU C CD  1 
ATOM   6332  O  OE1 . GLU C 1 110 ? 291.114 219.366 250.127 1.00 55.02  ? 110 GLU C OE1 1 
ATOM   6333  O  OE2 . GLU C 1 110 ? 292.791 220.755 249.867 1.00 49.52  ? 110 GLU C OE2 1 
ATOM   6334  N  N   . ARG C 1 111 ? 286.302 219.816 248.638 1.00 41.78  ? 111 ARG C N   1 
ATOM   6335  C  CA  . ARG C 1 111 ? 285.164 219.036 249.110 1.00 46.82  ? 111 ARG C CA  1 
ATOM   6336  C  C   . ARG C 1 111 ? 284.744 217.960 248.115 1.00 45.29  ? 111 ARG C C   1 
ATOM   6337  O  O   . ARG C 1 111 ? 284.255 216.903 248.526 1.00 53.37  ? 111 ARG C O   1 
ATOM   6338  C  CB  . ARG C 1 111 ? 283.984 219.956 249.422 1.00 43.52  ? 111 ARG C CB  1 
ATOM   6339  C  CG  . ARG C 1 111 ? 284.362 221.147 250.274 1.00 41.19  ? 111 ARG C CG  1 
ATOM   6340  C  CD  . ARG C 1 111 ? 283.303 221.443 251.311 1.00 41.73  ? 111 ARG C CD  1 
ATOM   6341  N  NE  . ARG C 1 111 ? 283.858 222.166 252.447 1.00 44.31  ? 111 ARG C NE  1 
ATOM   6342  C  CZ  . ARG C 1 111 ? 283.342 223.277 252.951 1.00 45.92  ? 111 ARG C CZ  1 
ATOM   6343  N  NH1 . ARG C 1 111 ? 282.253 223.827 252.440 1.00 41.93  ? 111 ARG C NH1 1 
ATOM   6344  N  NH2 . ARG C 1 111 ? 283.936 223.854 253.991 1.00 46.36  ? 111 ARG C NH2 1 
ATOM   6345  N  N   . LEU C 1 112 ? 284.915 218.205 246.815 1.00 42.88  ? 112 LEU C N   1 
ATOM   6346  C  CA  . LEU C 1 112 ? 284.549 217.202 245.820 1.00 41.42  ? 112 LEU C CA  1 
ATOM   6347  C  C   . LEU C 1 112 ? 285.378 215.937 245.988 1.00 49.63  ? 112 LEU C C   1 
ATOM   6348  O  O   . LEU C 1 112 ? 284.838 214.826 246.032 1.00 58.71  ? 112 LEU C O   1 
ATOM   6349  C  CB  . LEU C 1 112 ? 284.720 217.772 244.412 1.00 42.95  ? 112 LEU C CB  1 
ATOM   6350  C  CG  . LEU C 1 112 ? 283.688 218.805 243.962 1.00 45.96  ? 112 LEU C CG  1 
ATOM   6351  C  CD1 . LEU C 1 112 ? 283.985 219.273 242.546 1.00 47.29  ? 112 LEU C CD1 1 
ATOM   6352  C  CD2 . LEU C 1 112 ? 282.285 218.232 244.060 1.00 44.69  ? 112 LEU C CD2 1 
ATOM   6353  N  N   . ALA C 1 113 ? 286.699 216.085 246.078 1.00 50.99  ? 113 ALA C N   1 
ATOM   6354  C  CA  . ALA C 1 113 ? 287.576 214.947 246.318 1.00 52.83  ? 113 ALA C CA  1 
ATOM   6355  C  C   . ALA C 1 113 ? 287.646 214.647 247.809 1.00 57.30  ? 113 ALA C C   1 
ATOM   6356  O  O   . ALA C 1 113 ? 288.736 214.579 248.385 1.00 65.00  ? 113 ALA C O   1 
ATOM   6357  C  CB  . ALA C 1 113 ? 288.974 215.217 245.760 1.00 54.65  ? 113 ALA C CB  1 
ATOM   6358  N  N   . ASP C 1 114 ? 286.486 214.466 248.441 1.00 56.34  ? 114 ASP C N   1 
ATOM   6359  C  CA  . ASP C 1 114 ? 286.411 214.258 249.874 1.00 61.45  ? 114 ASP C CA  1 
ATOM   6360  C  C   . ASP C 1 114 ? 285.347 213.204 250.164 1.00 70.85  ? 114 ASP C C   1 
ATOM   6361  O  O   . ASP C 1 114 ? 284.213 213.321 249.666 1.00 68.83  ? 114 ASP C O   1 
ATOM   6362  C  CB  . ASP C 1 114 ? 286.082 215.565 250.600 1.00 61.45  ? 114 ASP C CB  1 
ATOM   6363  C  CG  . ASP C 1 114 ? 286.184 215.439 252.104 1.00 71.08  ? 114 ASP C CG  1 
ATOM   6364  O  OD1 . ASP C 1 114 ? 286.992 214.617 252.581 1.00 73.48  ? 114 ASP C OD1 1 
ATOM   6365  O  OD2 . ASP C 1 114 ? 285.453 216.162 252.810 1.00 77.61  ? 114 ASP C OD2 1 
ATOM   6366  N  N   . PRO C 1 115 ? 285.669 212.176 250.951 1.00 76.05  ? 115 PRO C N   1 
ATOM   6367  C  CA  . PRO C 1 115 ? 284.646 211.173 251.290 1.00 72.48  ? 115 PRO C CA  1 
ATOM   6368  C  C   . PRO C 1 115 ? 283.448 211.756 252.016 1.00 72.33  ? 115 PRO C C   1 
ATOM   6369  O  O   . PRO C 1 115 ? 282.331 211.249 251.855 1.00 71.69  ? 115 PRO C O   1 
ATOM   6370  C  CB  . PRO C 1 115 ? 285.410 210.172 252.170 1.00 66.75  ? 115 PRO C CB  1 
ATOM   6371  C  CG  . PRO C 1 115 ? 286.861 210.437 251.905 1.00 67.04  ? 115 PRO C CG  1 
ATOM   6372  C  CD  . PRO C 1 115 ? 286.962 211.892 251.592 1.00 68.39  ? 115 PRO C CD  1 
ATOM   6373  N  N   . ALA C 1 116 ? 283.644 212.803 252.820 1.00 72.51  ? 116 ALA C N   1 
ATOM   6374  C  CA  . ALA C 1 116 ? 282.543 213.350 253.605 1.00 74.04  ? 116 ALA C CA  1 
ATOM   6375  C  C   . ALA C 1 116 ? 281.426 213.867 252.707 1.00 72.26  ? 116 ALA C C   1 
ATOM   6376  O  O   . ALA C 1 116 ? 280.245 213.582 252.938 1.00 70.11  ? 116 ALA C O   1 
ATOM   6377  C  CB  . ALA C 1 116 ? 283.055 214.460 254.523 1.00 72.73  ? 116 ALA C CB  1 
ATOM   6378  N  N   . TYR C 1 117 ? 281.778 214.633 251.676 1.00 71.86  ? 117 TYR C N   1 
ATOM   6379  C  CA  . TYR C 1 117 ? 280.780 215.147 250.743 1.00 69.39  ? 117 TYR C CA  1 
ATOM   6380  C  C   . TYR C 1 117 ? 280.641 214.245 249.519 1.00 73.57  ? 117 TYR C C   1 
ATOM   6381  O  O   . TYR C 1 117 ? 279.568 213.691 249.263 1.00 80.61  ? 117 TYR C O   1 
ATOM   6382  C  CB  . TYR C 1 117 ? 281.148 216.571 250.312 1.00 62.30  ? 117 TYR C CB  1 
ATOM   6383  C  CG  . TYR C 1 117 ? 280.938 217.625 251.375 1.00 58.67  ? 117 TYR C CG  1 
ATOM   6384  C  CD1 . TYR C 1 117 ? 279.704 218.238 251.538 1.00 56.38  ? 117 TYR C CD1 1 
ATOM   6385  C  CD2 . TYR C 1 117 ? 281.978 218.015 252.207 1.00 58.39  ? 117 TYR C CD2 1 
ATOM   6386  C  CE1 . TYR C 1 117 ? 279.511 219.206 252.505 1.00 57.68  ? 117 TYR C CE1 1 
ATOM   6387  C  CE2 . TYR C 1 117 ? 281.793 218.981 253.176 1.00 54.17  ? 117 TYR C CE2 1 
ATOM   6388  C  CZ  . TYR C 1 117 ? 280.558 219.573 253.320 1.00 54.74  ? 117 TYR C CZ  1 
ATOM   6389  O  OH  . TYR C 1 117 ? 280.370 220.536 254.283 1.00 59.89  ? 117 TYR C OH  1 
ATOM   6390  N  N   . GLY C 1 118 ? 281.726 214.082 248.766 1.00 67.47  ? 118 GLY C N   1 
ATOM   6391  C  CA  . GLY C 1 118 ? 281.721 213.263 247.570 1.00 69.00  ? 118 GLY C CA  1 
ATOM   6392  C  C   . GLY C 1 118 ? 282.615 212.046 247.678 1.00 76.79  ? 118 GLY C C   1 
ATOM   6393  O  O   . GLY C 1 118 ? 282.240 211.034 248.279 1.00 77.58  ? 118 GLY C O   1 
ATOM   6394  N  N   . GLY C 1 119 ? 283.808 212.139 247.097 1.00 70.73  ? 119 GLY C N   1 
ATOM   6395  C  CA  . GLY C 1 119 ? 284.759 211.048 247.128 1.00 67.26  ? 119 GLY C CA  1 
ATOM   6396  C  C   . GLY C 1 119 ? 285.537 210.908 245.837 1.00 72.14  ? 119 GLY C C   1 
ATOM   6397  O  O   . GLY C 1 119 ? 286.415 210.049 245.726 1.00 78.35  ? 119 GLY C O   1 
ATOM   6398  N  N   . ASN C 1 120 ? 285.225 211.750 244.852 1.00 68.27  ? 120 ASN C N   1 
ATOM   6399  C  CA  . ASN C 1 120 ? 285.896 211.698 243.559 1.00 69.19  ? 120 ASN C CA  1 
ATOM   6400  C  C   . ASN C 1 120 ? 287.381 212.009 243.700 1.00 70.70  ? 120 ASN C C   1 
ATOM   6401  O  O   . ASN C 1 120 ? 287.759 213.151 243.981 1.00 70.88  ? 120 ASN C O   1 
ATOM   6402  C  CB  . ASN C 1 120 ? 285.236 212.674 242.584 1.00 69.82  ? 120 ASN C CB  1 
ATOM   6403  C  CG  . ASN C 1 120 ? 285.367 212.236 241.142 1.00 74.52  ? 120 ASN C CG  1 
ATOM   6404  O  OD1 . ASN C 1 120 ? 286.056 211.264 240.836 1.00 78.70  ? 120 ASN C OD1 1 
ATOM   6405  N  ND2 . ASN C 1 120 ? 284.701 212.951 240.244 1.00 68.88  ? 120 ASN C ND2 1 
ATOM   6406  N  N   . GLU C 1 121 ? 288.232 210.999 243.496 1.00 76.34  ? 121 GLU C N   1 
ATOM   6407  C  CA  . GLU C 1 121 ? 289.671 211.186 243.649 1.00 76.34  ? 121 GLU C CA  1 
ATOM   6408  C  C   . GLU C 1 121 ? 290.273 212.038 242.540 1.00 71.95  ? 121 GLU C C   1 
ATOM   6409  O  O   . GLU C 1 121 ? 291.397 212.526 242.694 1.00 73.08  ? 121 GLU C O   1 
ATOM   6410  C  CB  . GLU C 1 121 ? 290.385 209.833 243.688 1.00 78.86  ? 121 GLU C CB  1 
ATOM   6411  C  CG  . GLU C 1 121 ? 289.536 208.673 244.182 1.00 83.60  ? 121 GLU C CG  1 
ATOM   6412  C  CD  . GLU C 1 121 ? 288.982 208.903 245.573 1.00 83.31  ? 121 GLU C CD  1 
ATOM   6413  O  OE1 . GLU C 1 121 ? 289.392 209.887 246.221 1.00 83.54  ? 121 GLU C OE1 1 
ATOM   6414  O  OE2 . GLU C 1 121 ? 288.135 208.100 246.018 1.00 79.11  ? 121 GLU C OE2 1 
ATOM   6415  N  N   . GLU C 1 122 ? 289.561 212.222 241.428 1.00 68.37  ? 122 GLU C N   1 
ATOM   6416  C  CA  . GLU C 1 122 ? 290.120 212.955 240.300 1.00 74.27  ? 122 GLU C CA  1 
ATOM   6417  C  C   . GLU C 1 122 ? 290.354 214.428 240.606 1.00 75.14  ? 122 GLU C C   1 
ATOM   6418  O  O   . GLU C 1 122 ? 291.054 215.096 239.838 1.00 77.63  ? 122 GLU C O   1 
ATOM   6419  C  CB  . GLU C 1 122 ? 289.207 212.817 239.080 1.00 80.55  ? 122 GLU C CB  1 
ATOM   6420  C  CG  . GLU C 1 122 ? 289.477 211.576 238.241 1.00 83.88  ? 122 GLU C CG  1 
ATOM   6421  C  CD  . GLU C 1 122 ? 288.204 210.878 237.803 1.00 92.33  ? 122 GLU C CD  1 
ATOM   6422  O  OE1 . GLU C 1 122 ? 287.108 211.355 238.166 1.00 91.87  ? 122 GLU C OE1 1 
ATOM   6423  O  OE2 . GLU C 1 122 ? 288.297 209.853 237.096 1.00 92.01  ? 122 GLU C OE2 1 
ATOM   6424  N  N   . TYR C 1 123 ? 289.798 214.947 241.697 1.00 68.27  ? 123 TYR C N   1 
ATOM   6425  C  CA  . TYR C 1 123 ? 289.970 216.343 242.072 1.00 62.78  ? 123 TYR C CA  1 
ATOM   6426  C  C   . TYR C 1 123 ? 291.129 216.558 243.038 1.00 67.68  ? 123 TYR C C   1 
ATOM   6427  O  O   . TYR C 1 123 ? 291.314 217.678 243.524 1.00 66.86  ? 123 TYR C O   1 
ATOM   6428  C  CB  . TYR C 1 123 ? 288.676 216.887 242.681 1.00 57.53  ? 123 TYR C CB  1 
ATOM   6429  C  CG  . TYR C 1 123 ? 287.548 217.006 241.686 1.00 61.29  ? 123 TYR C CG  1 
ATOM   6430  C  CD1 . TYR C 1 123 ? 287.524 218.035 240.756 1.00 62.85  ? 123 TYR C CD1 1 
ATOM   6431  C  CD2 . TYR C 1 123 ? 286.510 216.086 241.671 1.00 64.05  ? 123 TYR C CD2 1 
ATOM   6432  C  CE1 . TYR C 1 123 ? 286.497 218.146 239.842 1.00 61.97  ? 123 TYR C CE1 1 
ATOM   6433  C  CE2 . TYR C 1 123 ? 285.479 216.189 240.759 1.00 66.42  ? 123 TYR C CE2 1 
ATOM   6434  C  CZ  . TYR C 1 123 ? 285.478 217.221 239.847 1.00 62.27  ? 123 TYR C CZ  1 
ATOM   6435  O  OH  . TYR C 1 123 ? 284.453 217.331 238.938 1.00 66.42  ? 123 TYR C OH  1 
ATOM   6436  N  N   . LYS C 1 124 ? 291.906 215.515 243.331 1.00 67.57  ? 124 LYS C N   1 
ATOM   6437  C  CA  . LYS C 1 124 ? 293.051 215.638 244.231 1.00 65.28  ? 124 LYS C CA  1 
ATOM   6438  C  C   . LYS C 1 124 ? 294.121 214.667 243.739 1.00 71.50  ? 124 LYS C C   1 
ATOM   6439  O  O   . LYS C 1 124 ? 294.011 213.457 243.958 1.00 75.72  ? 124 LYS C O   1 
ATOM   6440  C  CB  . LYS C 1 124 ? 292.655 215.355 245.674 1.00 66.21  ? 124 LYS C CB  1 
ATOM   6441  C  CG  . LYS C 1 124 ? 293.663 215.840 246.704 1.00 62.08  ? 124 LYS C CG  1 
ATOM   6442  C  CD  . LYS C 1 124 ? 293.312 217.228 247.208 1.00 59.65  ? 124 LYS C CD  1 
ATOM   6443  C  CE  . LYS C 1 124 ? 293.459 217.322 248.720 1.00 56.41  ? 124 LYS C CE  1 
ATOM   6444  N  NZ  . LYS C 1 124 ? 294.881 217.234 249.148 1.00 63.31  ? 124 LYS C NZ  1 
ATOM   6445  N  N   . ILE C 1 125 ? 295.144 215.203 243.083 1.00 74.59  ? 125 ILE C N   1 
ATOM   6446  C  CA  . ILE C 1 125 ? 296.218 214.388 242.526 1.00 79.94  ? 125 ILE C CA  1 
ATOM   6447  C  C   . ILE C 1 125 ? 297.205 214.045 243.635 1.00 81.90  ? 125 ILE C C   1 
ATOM   6448  O  O   . ILE C 1 125 ? 297.735 214.935 244.308 1.00 79.81  ? 125 ILE C O   1 
ATOM   6449  C  CB  . ILE C 1 125 ? 296.920 215.116 241.372 1.00 80.32  ? 125 ILE C CB  1 
ATOM   6450  C  CG1 . ILE C 1 125 ? 296.015 215.157 240.138 1.00 77.79  ? 125 ILE C CG1 1 
ATOM   6451  C  CG2 . ILE C 1 125 ? 298.247 214.448 241.050 1.00 82.08  ? 125 ILE C CG2 1 
ATOM   6452  C  CD1 . ILE C 1 125 ? 296.766 215.348 238.837 1.00 73.71  ? 125 ILE C CD1 1 
ATOM   6453  N  N   . THR C 1 126 ? 297.454 212.748 243.826 1.00 88.71  ? 126 THR C N   1 
ATOM   6454  C  CA  . THR C 1 126 ? 298.426 212.277 244.800 1.00 95.03  ? 126 THR C CA  1 
ATOM   6455  C  C   . THR C 1 126 ? 299.600 211.530 244.188 1.00 101.72 ? 126 THR C C   1 
ATOM   6456  O  O   . THR C 1 126 ? 300.642 211.418 244.842 1.00 103.18 ? 126 THR C O   1 
ATOM   6457  C  CB  . THR C 1 126 ? 297.753 211.363 245.837 1.00 93.66  ? 126 THR C CB  1 
ATOM   6458  O  OG1 . THR C 1 126 ? 297.333 210.148 245.203 1.00 97.79  ? 126 THR C OG1 1 
ATOM   6459  C  CG2 . THR C 1 126 ? 296.545 212.052 246.451 1.00 86.94  ? 126 THR C CG2 1 
ATOM   6460  N  N   . GLU C 1 127 ? 299.470 211.023 242.965 1.00 105.66 ? 127 GLU C N   1 
ATOM   6461  C  CA  . GLU C 1 127 ? 300.549 210.327 242.283 1.00 114.05 ? 127 GLU C CA  1 
ATOM   6462  C  C   . GLU C 1 127 ? 300.721 210.904 240.886 1.00 117.81 ? 127 GLU C C   1 
ATOM   6463  O  O   . GLU C 1 127 ? 299.765 211.390 240.275 1.00 116.65 ? 127 GLU C O   1 
ATOM   6464  C  CB  . GLU C 1 127 ? 300.283 208.818 242.191 1.00 117.67 ? 127 GLU C CB  1 
ATOM   6465  C  CG  . GLU C 1 127 ? 300.472 208.069 243.497 1.00 117.35 ? 127 GLU C CG  1 
ATOM   6466  C  CD  . GLU C 1 127 ? 299.452 206.963 243.684 1.00 119.33 ? 127 GLU C CD  1 
ATOM   6467  O  OE1 . GLU C 1 127 ? 298.243 207.232 243.519 1.00 114.61 ? 127 GLU C OE1 1 
ATOM   6468  O  OE2 . GLU C 1 127 ? 299.858 205.824 243.995 1.00 121.49 ? 127 GLU C OE2 1 
ATOM   6469  N  N   . ASN C 1 128 ? 301.950 210.846 240.384 1.00 122.02 ? 128 ASN C N   1 
ATOM   6470  C  CA  . ASN C 1 128 ? 302.251 211.344 239.050 1.00 129.10 ? 128 ASN C CA  1 
ATOM   6471  C  C   . ASN C 1 128 ? 301.878 210.282 238.017 1.00 134.23 ? 128 ASN C C   1 
ATOM   6472  O  O   . ASN C 1 128 ? 301.279 209.251 238.336 1.00 133.42 ? 128 ASN C O   1 
ATOM   6473  C  CB  . ASN C 1 128 ? 303.719 211.751 238.956 1.00 129.19 ? 128 ASN C CB  1 
ATOM   6474  C  CG  . ASN C 1 128 ? 304.024 213.013 239.738 1.00 130.38 ? 128 ASN C CG  1 
ATOM   6475  O  OD1 . ASN C 1 128 ? 303.177 213.897 239.866 1.00 128.90 ? 128 ASN C OD1 1 
ATOM   6476  N  ND2 . ASN C 1 128 ? 305.237 213.101 240.272 1.00 129.77 ? 128 ASN C ND2 1 
ATOM   6477  N  N   . LYS C 1 129 ? 302.231 210.526 236.755 1.00 135.49 ? 129 LYS C N   1 
ATOM   6478  C  CA  . LYS C 1 129 ? 301.940 209.566 235.698 1.00 135.89 ? 129 LYS C CA  1 
ATOM   6479  C  C   . LYS C 1 129 ? 302.708 208.262 235.860 1.00 136.98 ? 129 LYS C C   1 
ATOM   6480  O  O   . LYS C 1 129 ? 302.368 207.278 235.194 1.00 135.71 ? 129 LYS C O   1 
ATOM   6481  C  CB  . LYS C 1 129 ? 302.255 210.178 234.331 1.00 133.92 ? 129 LYS C CB  1 
ATOM   6482  C  CG  . LYS C 1 129 ? 301.414 211.395 233.985 1.00 132.03 ? 129 LYS C CG  1 
ATOM   6483  C  CD  . LYS C 1 129 ? 302.216 212.677 234.133 1.00 130.69 ? 129 LYS C CD  1 
ATOM   6484  C  CE  . LYS C 1 129 ? 301.491 213.856 233.505 1.00 124.61 ? 129 LYS C CE  1 
ATOM   6485  N  NZ  . LYS C 1 129 ? 302.243 215.129 233.681 1.00 116.68 ? 129 LYS C NZ  1 
ATOM   6486  N  N   . PHE C 1 130 ? 303.725 208.229 236.720 1.00 136.83 ? 130 PHE C N   1 
ATOM   6487  C  CA  . PHE C 1 130 ? 304.560 207.051 236.901 1.00 135.56 ? 130 PHE C CA  1 
ATOM   6488  C  C   . PHE C 1 130 ? 304.285 206.316 238.205 1.00 133.86 ? 130 PHE C C   1 
ATOM   6489  O  O   . PHE C 1 130 ? 304.931 205.298 238.473 1.00 134.42 ? 130 PHE C O   1 
ATOM   6490  C  CB  . PHE C 1 130 ? 306.042 207.438 236.829 1.00 136.31 ? 130 PHE C CB  1 
ATOM   6491  C  CG  . PHE C 1 130 ? 306.346 208.503 235.809 1.00 136.60 ? 130 PHE C CG  1 
ATOM   6492  C  CD1 . PHE C 1 130 ? 305.739 208.484 234.563 1.00 137.16 ? 130 PHE C CD1 1 
ATOM   6493  C  CD2 . PHE C 1 130 ? 307.240 209.520 236.096 1.00 135.63 ? 130 PHE C CD2 1 
ATOM   6494  C  CE1 . PHE C 1 130 ? 306.016 209.460 233.627 1.00 137.61 ? 130 PHE C CE1 1 
ATOM   6495  C  CE2 . PHE C 1 130 ? 307.522 210.499 235.162 1.00 135.32 ? 130 PHE C CE2 1 
ATOM   6496  C  CZ  . PHE C 1 130 ? 306.909 210.469 233.927 1.00 137.27 ? 130 PHE C CZ  1 
ATOM   6497  N  N   . GLY C 1 131 ? 303.351 206.800 239.022 1.00 133.19 ? 131 GLY C N   1 
ATOM   6498  C  CA  . GLY C 1 131 ? 303.023 206.159 240.277 1.00 128.44 ? 131 GLY C CA  1 
ATOM   6499  C  C   . GLY C 1 131 ? 303.851 206.596 241.465 1.00 127.66 ? 131 GLY C C   1 
ATOM   6500  O  O   . GLY C 1 131 ? 303.577 206.150 242.586 1.00 124.13 ? 131 GLY C O   1 
ATOM   6501  N  N   . GLU C 1 132 ? 304.848 207.446 241.263 1.00 131.09 ? 132 GLU C N   1 
ATOM   6502  C  CA  . GLU C 1 132 ? 305.677 207.896 242.373 1.00 129.53 ? 132 GLU C CA  1 
ATOM   6503  C  C   . GLU C 1 132 ? 304.872 208.824 243.277 1.00 128.97 ? 132 GLU C C   1 
ATOM   6504  O  O   . GLU C 1 132 ? 304.256 209.778 242.786 1.00 126.36 ? 132 GLU C O   1 
ATOM   6505  C  CB  . GLU C 1 132 ? 306.929 208.608 241.860 1.00 128.65 ? 132 GLU C CB  1 
ATOM   6506  C  CG  . GLU C 1 132 ? 306.695 210.026 241.352 1.00 128.90 ? 132 GLU C CG  1 
ATOM   6507  C  CD  . GLU C 1 132 ? 306.357 210.078 239.873 1.00 132.28 ? 132 GLU C CD  1 
ATOM   6508  O  OE1 . GLU C 1 132 ? 305.623 209.190 239.392 1.00 131.98 ? 132 GLU C OE1 1 
ATOM   6509  O  OE2 . GLU C 1 132 ? 306.828 211.011 239.189 1.00 132.89 ? 132 GLU C OE2 1 
ATOM   6510  N  N   . PRO C 1 133 ? 304.841 208.580 244.585 1.00 127.05 ? 133 PRO C N   1 
ATOM   6511  C  CA  . PRO C 1 133 ? 304.081 209.464 245.477 1.00 119.91 ? 133 PRO C CA  1 
ATOM   6512  C  C   . PRO C 1 133 ? 304.580 210.898 245.383 1.00 117.77 ? 133 PRO C C   1 
ATOM   6513  O  O   . PRO C 1 133 ? 305.781 211.154 245.275 1.00 117.83 ? 133 PRO C O   1 
ATOM   6514  C  CB  . PRO C 1 133 ? 304.331 208.868 246.867 1.00 114.61 ? 133 PRO C CB  1 
ATOM   6515  C  CG  . PRO C 1 133 ? 304.740 207.453 246.612 1.00 116.87 ? 133 PRO C CG  1 
ATOM   6516  C  CD  . PRO C 1 133 ? 305.482 207.473 245.313 1.00 122.31 ? 133 PRO C CD  1 
ATOM   6517  N  N   . VAL C 1 134 ? 303.638 211.838 245.423 1.00 111.45 ? 134 VAL C N   1 
ATOM   6518  C  CA  . VAL C 1 134 ? 303.921 213.258 245.306 1.00 105.30 ? 134 VAL C CA  1 
ATOM   6519  C  C   . VAL C 1 134 ? 303.066 214.007 246.324 1.00 97.99  ? 134 VAL C C   1 
ATOM   6520  O  O   . VAL C 1 134 ? 302.274 213.414 247.055 1.00 96.36  ? 134 VAL C O   1 
ATOM   6521  C  CB  . VAL C 1 134 ? 303.672 213.785 243.877 1.00 104.89 ? 134 VAL C CB  1 
ATOM   6522  C  CG1 . VAL C 1 134 ? 302.184 213.965 243.628 1.00 99.28  ? 134 VAL C CG1 1 
ATOM   6523  C  CG2 . VAL C 1 134 ? 304.428 215.085 243.644 1.00 103.21 ? 134 VAL C CG2 1 
ATOM   6524  N  N   . THR C 1 135 ? 303.238 215.320 246.365 1.00 94.18  ? 135 THR C N   1 
ATOM   6525  C  CA  . THR C 1 135 ? 302.447 216.155 247.261 1.00 90.63  ? 135 THR C CA  1 
ATOM   6526  C  C   . THR C 1 135 ? 301.016 216.235 246.748 1.00 88.56  ? 135 THR C C   1 
ATOM   6527  O  O   . THR C 1 135 ? 300.802 216.668 245.608 1.00 84.67  ? 135 THR C O   1 
ATOM   6528  C  CB  . THR C 1 135 ? 303.051 217.554 247.361 1.00 86.51  ? 135 THR C CB  1 
ATOM   6529  O  OG1 . THR C 1 135 ? 304.479 217.468 247.280 1.00 87.70  ? 135 THR C OG1 1 
ATOM   6530  C  CG2 . THR C 1 135 ? 302.662 218.210 248.677 1.00 83.29  ? 135 THR C CG2 1 
ATOM   6531  N  N   . PRO C 1 136 ? 300.017 215.830 247.529 1.00 86.89  ? 136 PRO C N   1 
ATOM   6532  C  CA  . PRO C 1 136 ? 298.633 215.931 247.055 1.00 80.79  ? 136 PRO C CA  1 
ATOM   6533  C  C   . PRO C 1 136 ? 298.268 217.375 246.751 1.00 76.02  ? 136 PRO C C   1 
ATOM   6534  O  O   . PRO C 1 136 ? 298.628 218.296 247.486 1.00 75.65  ? 136 PRO C O   1 
ATOM   6535  C  CB  . PRO C 1 136 ? 297.811 215.372 248.222 1.00 78.39  ? 136 PRO C CB  1 
ATOM   6536  C  CG  . PRO C 1 136 ? 298.778 214.577 249.038 1.00 80.65  ? 136 PRO C CG  1 
ATOM   6537  C  CD  . PRO C 1 136 ? 300.106 215.244 248.876 1.00 81.61  ? 136 PRO C CD  1 
ATOM   6538  N  N   . HIS C 1 137 ? 297.542 217.567 245.653 1.00 72.07  ? 137 HIS C N   1 
ATOM   6539  C  CA  . HIS C 1 137 ? 297.167 218.905 245.221 1.00 67.90  ? 137 HIS C CA  1 
ATOM   6540  C  C   . HIS C 1 137 ? 295.965 218.804 244.298 1.00 64.33  ? 137 HIS C C   1 
ATOM   6541  O  O   . HIS C 1 137 ? 295.641 217.732 243.783 1.00 67.22  ? 137 HIS C O   1 
ATOM   6542  C  CB  . HIS C 1 137 ? 298.333 219.617 244.528 1.00 67.09  ? 137 HIS C CB  1 
ATOM   6543  C  CG  . HIS C 1 137 ? 298.812 218.926 243.291 1.00 68.87  ? 137 HIS C CG  1 
ATOM   6544  N  ND1 . HIS C 1 137 ? 299.501 217.733 243.326 1.00 73.53  ? 137 HIS C ND1 1 
ATOM   6545  C  CD2 . HIS C 1 137 ? 298.704 219.260 241.983 1.00 66.67  ? 137 HIS C CD2 1 
ATOM   6546  C  CE1 . HIS C 1 137 ? 299.794 217.360 242.093 1.00 75.47  ? 137 HIS C CE1 1 
ATOM   6547  N  NE2 . HIS C 1 137 ? 299.322 218.270 241.259 1.00 68.70  ? 137 HIS C NE2 1 
ATOM   6548  N  N   . LEU C 1 138 ? 295.307 219.940 244.097 1.00 59.00  ? 138 LEU C N   1 
ATOM   6549  C  CA  . LEU C 1 138 ? 294.098 219.988 243.294 1.00 59.06  ? 138 LEU C CA  1 
ATOM   6550  C  C   . LEU C 1 138 ? 294.426 219.930 241.809 1.00 59.64  ? 138 LEU C C   1 
ATOM   6551  O  O   . LEU C 1 138 ? 295.432 220.475 241.348 1.00 60.52  ? 138 LEU C O   1 
ATOM   6552  C  CB  . LEU C 1 138 ? 293.306 221.260 243.596 1.00 54.15  ? 138 LEU C CB  1 
ATOM   6553  C  CG  . LEU C 1 138 ? 292.883 221.460 245.049 1.00 49.28  ? 138 LEU C CG  1 
ATOM   6554  C  CD1 . LEU C 1 138 ? 292.187 222.799 245.212 1.00 42.29  ? 138 LEU C CD1 1 
ATOM   6555  C  CD2 . LEU C 1 138 ? 291.990 220.322 245.505 1.00 44.34  ? 138 LEU C CD2 1 
ATOM   6556  N  N   . ASP C 1 139 ? 293.557 219.258 241.058 1.00 60.83  ? 139 ASP C N   1 
ATOM   6557  C  CA  . ASP C 1 139 ? 293.667 219.183 239.604 1.00 65.04  ? 139 ASP C CA  1 
ATOM   6558  C  C   . ASP C 1 139 ? 292.769 220.271 239.025 1.00 65.31  ? 139 ASP C C   1 
ATOM   6559  O  O   . ASP C 1 139 ? 291.576 220.066 238.801 1.00 68.80  ? 139 ASP C O   1 
ATOM   6560  C  CB  . ASP C 1 139 ? 293.282 217.798 239.098 1.00 71.59  ? 139 ASP C CB  1 
ATOM   6561  C  CG  . ASP C 1 139 ? 293.773 217.537 237.691 1.00 75.98  ? 139 ASP C CG  1 
ATOM   6562  O  OD1 . ASP C 1 139 ? 294.463 218.414 237.131 1.00 72.03  ? 139 ASP C OD1 1 
ATOM   6563  O  OD2 . ASP C 1 139 ? 293.468 216.457 237.144 1.00 75.62  ? 139 ASP C OD2 1 
ATOM   6564  N  N   . TRP C 1 140 ? 293.353 221.444 238.782 1.00 60.93  ? 140 TRP C N   1 
ATOM   6565  C  CA  . TRP C 1 140 ? 292.584 222.573 238.278 1.00 60.71  ? 140 TRP C CA  1 
ATOM   6566  C  C   . TRP C 1 140 ? 292.216 222.430 236.807 1.00 63.59  ? 140 TRP C C   1 
ATOM   6567  O  O   . TRP C 1 140 ? 291.453 223.256 236.297 1.00 63.38  ? 140 TRP C O   1 
ATOM   6568  C  CB  . TRP C 1 140 ? 293.360 223.873 238.493 1.00 54.34  ? 140 TRP C CB  1 
ATOM   6569  C  CG  . TRP C 1 140 ? 293.465 224.275 239.933 1.00 54.16  ? 140 TRP C CG  1 
ATOM   6570  C  CD1 . TRP C 1 140 ? 294.415 223.878 240.825 1.00 54.29  ? 140 TRP C CD1 1 
ATOM   6571  C  CD2 . TRP C 1 140 ? 292.587 225.154 240.647 1.00 46.63  ? 140 TRP C CD2 1 
ATOM   6572  N  NE1 . TRP C 1 140 ? 294.185 224.454 242.050 1.00 49.09  ? 140 TRP C NE1 1 
ATOM   6573  C  CE2 . TRP C 1 140 ? 293.069 225.242 241.967 1.00 46.41  ? 140 TRP C CE2 1 
ATOM   6574  C  CE3 . TRP C 1 140 ? 291.442 225.875 240.298 1.00 40.22  ? 140 TRP C CE3 1 
ATOM   6575  C  CZ2 . TRP C 1 140 ? 292.445 226.020 242.938 1.00 40.18  ? 140 TRP C CZ2 1 
ATOM   6576  C  CZ3 . TRP C 1 140 ? 290.825 226.647 241.263 1.00 38.11  ? 140 TRP C CZ3 1 
ATOM   6577  C  CH2 . TRP C 1 140 ? 291.327 226.714 242.566 1.00 37.68  ? 140 TRP C CH2 1 
ATOM   6578  N  N   . SER C 1 141 ? 292.737 221.413 236.117 1.00 68.44  ? 141 SER C N   1 
ATOM   6579  C  CA  . SER C 1 141 ? 292.431 221.249 234.699 1.00 69.44  ? 141 SER C CA  1 
ATOM   6580  C  C   . SER C 1 141 ? 290.984 220.817 234.490 1.00 71.94  ? 141 SER C C   1 
ATOM   6581  O  O   . SER C 1 141 ? 290.283 221.361 233.630 1.00 75.34  ? 141 SER C O   1 
ATOM   6582  C  CB  . SER C 1 141 ? 293.391 220.240 234.069 1.00 71.53  ? 141 SER C CB  1 
ATOM   6583  O  OG  . SER C 1 141 ? 293.423 219.032 234.809 1.00 76.10  ? 141 SER C OG  1 
ATOM   6584  N  N   . LYS C 1 142 ? 290.519 219.844 235.265 1.00 68.14  ? 142 LYS C N   1 
ATOM   6585  C  CA  . LYS C 1 142 ? 289.170 219.324 235.070 1.00 68.20  ? 142 LYS C CA  1 
ATOM   6586  C  C   . LYS C 1 142 ? 288.143 220.319 235.601 1.00 67.42  ? 142 LYS C C   1 
ATOM   6587  O  O   . LYS C 1 142 ? 288.227 220.728 236.763 1.00 66.60  ? 142 LYS C O   1 
ATOM   6588  C  CB  . LYS C 1 142 ? 289.005 217.974 235.762 1.00 69.97  ? 142 LYS C CB  1 
ATOM   6589  C  CG  . LYS C 1 142 ? 289.054 218.027 237.276 1.00 72.41  ? 142 LYS C CG  1 
ATOM   6590  C  CD  . LYS C 1 142 ? 289.150 216.631 237.869 1.00 72.01  ? 142 LYS C CD  1 
ATOM   6591  C  CE  . LYS C 1 142 ? 288.371 215.615 237.044 1.00 73.81  ? 142 LYS C CE  1 
ATOM   6592  N  NZ  . LYS C 1 142 ? 286.955 216.019 236.826 1.00 72.25  ? 142 LYS C NZ  1 
ATOM   6593  N  N   . PRO C 1 143 ? 287.174 220.731 234.788 1.00 72.39  ? 143 PRO C N   1 
ATOM   6594  C  CA  . PRO C 1 143 ? 286.207 221.735 235.243 1.00 72.87  ? 143 PRO C CA  1 
ATOM   6595  C  C   . PRO C 1 143 ? 285.321 221.211 236.361 1.00 69.00  ? 143 PRO C C   1 
ATOM   6596  O  O   . PRO C 1 143 ? 285.049 220.012 236.466 1.00 70.79  ? 143 PRO C O   1 
ATOM   6597  C  CB  . PRO C 1 143 ? 285.385 222.037 233.982 1.00 67.50  ? 143 PRO C CB  1 
ATOM   6598  C  CG  . PRO C 1 143 ? 286.219 221.535 232.840 1.00 69.19  ? 143 PRO C CG  1 
ATOM   6599  C  CD  . PRO C 1 143 ? 286.966 220.360 233.380 1.00 69.84  ? 143 PRO C CD  1 
ATOM   6600  N  N   . ILE C 1 144 ? 284.876 222.133 237.205 1.00 65.47  ? 144 ILE C N   1 
ATOM   6601  C  CA  . ILE C 1 144 ? 283.930 221.786 238.272 1.00 63.94  ? 144 ILE C CA  1 
ATOM   6602  C  C   . ILE C 1 144 ? 282.597 221.396 237.648 1.00 68.75  ? 144 ILE C C   1 
ATOM   6603  O  O   . ILE C 1 144 ? 282.209 221.974 236.616 1.00 67.92  ? 144 ILE C O   1 
ATOM   6604  C  CB  . ILE C 1 144 ? 283.764 222.962 239.237 1.00 60.27  ? 144 ILE C CB  1 
ATOM   6605  C  CG1 . ILE C 1 144 ? 284.986 223.084 240.149 1.00 51.36  ? 144 ILE C CG1 1 
ATOM   6606  C  CG2 . ILE C 1 144 ? 282.494 222.807 240.060 1.00 53.78  ? 144 ILE C CG2 1 
ATOM   6607  C  CD1 . ILE C 1 144 ? 285.064 224.398 240.888 1.00 38.35  ? 144 ILE C CD1 1 
ATOM   6608  N  N   . PRO C 1 145 ? 281.867 220.437 238.215 1.00 68.27  ? 145 PRO C N   1 
ATOM   6609  C  CA  . PRO C 1 145 ? 280.567 220.072 237.640 1.00 68.19  ? 145 PRO C CA  1 
ATOM   6610  C  C   . PRO C 1 145 ? 279.615 221.258 237.630 1.00 71.85  ? 145 PRO C C   1 
ATOM   6611  O  O   . PRO C 1 145 ? 279.580 222.060 238.565 1.00 72.29  ? 145 PRO C O   1 
ATOM   6612  C  CB  . PRO C 1 145 ? 280.066 218.958 238.568 1.00 69.72  ? 145 PRO C CB  1 
ATOM   6613  C  CG  . PRO C 1 145 ? 281.269 218.483 239.310 1.00 67.66  ? 145 PRO C CG  1 
ATOM   6614  C  CD  . PRO C 1 145 ? 282.186 219.655 239.419 1.00 68.01  ? 145 PRO C CD  1 
ATOM   6615  N  N   . SER C 1 146 ? 278.837 221.363 236.557 1.00 75.01  ? 146 SER C N   1 
ATOM   6616  C  CA  . SER C 1 146 ? 277.799 222.378 236.481 1.00 77.70  ? 146 SER C CA  1 
ATOM   6617  C  C   . SER C 1 146 ? 276.599 221.957 237.319 1.00 83.89  ? 146 SER C C   1 
ATOM   6618  O  O   . SER C 1 146 ? 276.293 220.769 237.450 1.00 87.17  ? 146 SER C O   1 
ATOM   6619  C  CB  . SER C 1 146 ? 277.376 222.610 235.030 1.00 79.07  ? 146 SER C CB  1 
ATOM   6620  O  OG  . SER C 1 146 ? 276.083 223.185 234.963 1.00 82.70  ? 146 SER C OG  1 
ATOM   6621  N  N   . GLU C 1 147 ? 275.915 222.950 237.890 1.00 83.85  ? 147 GLU C N   1 
ATOM   6622  C  CA  . GLU C 1 147 ? 274.832 222.651 238.822 1.00 87.93  ? 147 GLU C CA  1 
ATOM   6623  C  C   . GLU C 1 147 ? 273.739 221.820 238.160 1.00 89.16  ? 147 GLU C C   1 
ATOM   6624  O  O   . GLU C 1 147 ? 273.207 220.885 238.768 1.00 87.81  ? 147 GLU C O   1 
ATOM   6625  C  CB  . GLU C 1 147 ? 274.256 223.947 239.393 1.00 88.06  ? 147 GLU C CB  1 
ATOM   6626  C  CG  . GLU C 1 147 ? 275.201 224.679 240.332 1.00 85.76  ? 147 GLU C CG  1 
ATOM   6627  C  CD  . GLU C 1 147 ? 274.523 225.809 241.082 1.00 88.71  ? 147 GLU C CD  1 
ATOM   6628  O  OE1 . GLU C 1 147 ? 273.312 226.024 240.867 1.00 92.11  ? 147 GLU C OE1 1 
ATOM   6629  O  OE2 . GLU C 1 147 ? 275.202 226.479 241.890 1.00 83.08  ? 147 GLU C OE2 1 
ATOM   6630  N  N   . LYS C 1 148 ? 273.390 222.144 236.913 1.00 89.32  ? 148 LYS C N   1 
ATOM   6631  C  CA  . LYS C 1 148 ? 272.343 221.393 236.229 1.00 89.67  ? 148 LYS C CA  1 
ATOM   6632  C  C   . LYS C 1 148 ? 272.813 220.002 235.822 1.00 91.89  ? 148 LYS C C   1 
ATOM   6633  O  O   . LYS C 1 148 ? 272.000 219.075 235.740 1.00 94.29  ? 148 LYS C O   1 
ATOM   6634  C  CB  . LYS C 1 148 ? 271.854 222.167 235.005 1.00 92.40  ? 148 LYS C CB  1 
ATOM   6635  C  CG  . LYS C 1 148 ? 272.934 222.449 233.974 1.00 92.24  ? 148 LYS C CG  1 
ATOM   6636  C  CD  . LYS C 1 148 ? 272.384 223.258 232.810 1.00 95.56  ? 148 LYS C CD  1 
ATOM   6637  C  CE  . LYS C 1 148 ? 271.165 222.587 232.198 1.00 98.89  ? 148 LYS C CE  1 
ATOM   6638  N  NZ  . LYS C 1 148 ? 270.327 223.546 231.426 1.00 91.98  ? 148 LYS C NZ  1 
ATOM   6639  N  N   . ARG C 1 149 ? 274.109 219.835 235.563 1.00 92.80  ? 149 ARG C N   1 
ATOM   6640  C  CA  . ARG C 1 149 ? 274.666 218.566 235.115 1.00 93.06  ? 149 ARG C CA  1 
ATOM   6641  C  C   . ARG C 1 149 ? 275.355 217.787 236.229 1.00 91.58  ? 149 ARG C C   1 
ATOM   6642  O  O   . ARG C 1 149 ? 275.967 216.750 235.956 1.00 91.70  ? 149 ARG C O   1 
ATOM   6643  C  CB  . ARG C 1 149 ? 275.649 218.803 233.967 1.00 91.85  ? 149 ARG C CB  1 
ATOM   6644  C  CG  . ARG C 1 149 ? 274.998 218.861 232.596 1.00 97.28  ? 149 ARG C CG  1 
ATOM   6645  C  CD  . ARG C 1 149 ? 274.691 217.466 232.076 1.00 97.34  ? 149 ARG C CD  1 
ATOM   6646  N  NE  . ARG C 1 149 ? 275.846 216.582 232.174 1.00 102.19 ? 149 ARG C NE  1 
ATOM   6647  C  CZ  . ARG C 1 149 ? 275.915 215.524 232.970 1.00 100.29 ? 149 ARG C CZ  1 
ATOM   6648  N  NH1 . ARG C 1 149 ? 274.907 215.183 233.756 1.00 96.21  ? 149 ARG C NH1 1 
ATOM   6649  N  NH2 . ARG C 1 149 ? 277.023 214.788 232.976 1.00 95.29  ? 149 ARG C NH2 1 
ATOM   6650  N  N   . ALA C 1 150 ? 275.274 218.255 237.469 1.00 87.29  ? 150 ALA C N   1 
ATOM   6651  C  CA  . ALA C 1 150 ? 275.990 217.629 238.569 1.00 81.64  ? 150 ALA C CA  1 
ATOM   6652  C  C   . ALA C 1 150 ? 275.133 216.563 239.246 1.00 80.55  ? 150 ALA C C   1 
ATOM   6653  O  O   . ALA C 1 150 ? 273.903 216.642 239.280 1.00 82.06  ? 150 ALA C O   1 
ATOM   6654  C  CB  . ALA C 1 150 ? 276.425 218.678 239.593 1.00 74.80  ? 150 ALA C CB  1 
ATOM   6655  N  N   . THR C 1 151 ? 275.809 215.556 239.793 1.00 75.70  ? 151 THR C N   1 
ATOM   6656  C  CA  . THR C 1 151 ? 275.149 214.494 240.531 1.00 75.44  ? 151 THR C CA  1 
ATOM   6657  C  C   . THR C 1 151 ? 274.876 214.958 241.963 1.00 73.46  ? 151 THR C C   1 
ATOM   6658  O  O   . THR C 1 151 ? 275.239 216.066 242.364 1.00 73.21  ? 151 THR C O   1 
ATOM   6659  C  CB  . THR C 1 151 ? 275.993 213.219 240.494 1.00 73.91  ? 151 THR C CB  1 
ATOM   6660  O  OG1 . THR C 1 151 ? 275.415 212.226 241.350 1.00 81.54  ? 151 THR C OG1 1 
ATOM   6661  C  CG2 . THR C 1 151 ? 277.412 213.506 240.942 1.00 73.19  ? 151 THR C CG2 1 
ATOM   6662  N  N   . GLU C 1 152 ? 274.218 214.103 242.748 1.00 75.67  ? 152 GLU C N   1 
ATOM   6663  C  CA  . GLU C 1 152 ? 273.813 214.504 244.092 1.00 77.98  ? 152 GLU C CA  1 
ATOM   6664  C  C   . GLU C 1 152 ? 275.017 214.855 244.958 1.00 77.63  ? 152 GLU C C   1 
ATOM   6665  O  O   . GLU C 1 152 ? 275.001 215.862 245.676 1.00 76.29  ? 152 GLU C O   1 
ATOM   6666  C  CB  . GLU C 1 152 ? 272.988 213.393 244.741 1.00 82.60  ? 152 GLU C CB  1 
ATOM   6667  C  CG  . GLU C 1 152 ? 272.057 213.871 245.839 1.00 87.89  ? 152 GLU C CG  1 
ATOM   6668  C  CD  . GLU C 1 152 ? 271.959 212.886 246.986 1.00 94.25  ? 152 GLU C CD  1 
ATOM   6669  O  OE1 . GLU C 1 152 ? 272.822 212.934 247.888 1.00 95.04  ? 152 GLU C OE1 1 
ATOM   6670  O  OE2 . GLU C 1 152 ? 271.021 212.062 246.985 1.00 97.68  ? 152 GLU C OE2 1 
ATOM   6671  N  N   . GLU C 1 153 ? 276.072 214.039 244.907 1.00 78.01  ? 153 GLU C N   1 
ATOM   6672  C  CA  . GLU C 1 153 ? 277.259 214.324 245.707 1.00 74.25  ? 153 GLU C CA  1 
ATOM   6673  C  C   . GLU C 1 153 ? 277.941 215.607 245.249 1.00 67.89  ? 153 GLU C C   1 
ATOM   6674  O  O   . GLU C 1 153 ? 278.339 216.437 246.077 1.00 66.12  ? 153 GLU C O   1 
ATOM   6675  C  CB  . GLU C 1 153 ? 278.229 213.145 245.642 1.00 76.97  ? 153 GLU C CB  1 
ATOM   6676  C  CG  . GLU C 1 153 ? 277.909 212.029 246.620 1.00 78.18  ? 153 GLU C CG  1 
ATOM   6677  C  CD  . GLU C 1 153 ? 277.003 210.971 246.022 1.00 86.76  ? 153 GLU C CD  1 
ATOM   6678  O  OE1 . GLU C 1 153 ? 276.376 211.242 244.977 1.00 86.12  ? 153 GLU C OE1 1 
ATOM   6679  O  OE2 . GLU C 1 153 ? 276.916 209.867 246.600 1.00 85.68  ? 153 GLU C OE2 1 
ATOM   6680  N  N   . GLU C 1 154 ? 278.088 215.787 243.936 1.00 64.48  ? 154 GLU C N   1 
ATOM   6681  C  CA  . GLU C 1 154 ? 278.697 217.008 243.423 1.00 64.62  ? 154 GLU C CA  1 
ATOM   6682  C  C   . GLU C 1 154 ? 277.861 218.229 243.779 1.00 61.79  ? 154 GLU C C   1 
ATOM   6683  O  O   . GLU C 1 154 ? 278.403 219.282 244.131 1.00 61.59  ? 154 GLU C O   1 
ATOM   6684  C  CB  . GLU C 1 154 ? 278.883 216.906 241.910 1.00 67.69  ? 154 GLU C CB  1 
ATOM   6685  C  CG  . GLU C 1 154 ? 279.765 215.754 241.473 1.00 68.46  ? 154 GLU C CG  1 
ATOM   6686  C  CD  . GLU C 1 154 ? 279.746 215.551 239.973 1.00 77.64  ? 154 GLU C CD  1 
ATOM   6687  O  OE1 . GLU C 1 154 ? 278.691 215.801 239.355 1.00 81.71  ? 154 GLU C OE1 1 
ATOM   6688  O  OE2 . GLU C 1 154 ? 280.784 215.143 239.411 1.00 78.33  ? 154 GLU C OE2 1 
ATOM   6689  N  N   . ILE C 1 155 ? 276.536 218.110 243.686 1.00 63.02  ? 155 ILE C N   1 
ATOM   6690  C  CA  . ILE C 1 155 ? 275.665 219.226 244.040 1.00 58.81  ? 155 ILE C CA  1 
ATOM   6691  C  C   . ILE C 1 155 ? 275.809 219.565 245.517 1.00 56.13  ? 155 ILE C C   1 
ATOM   6692  O  O   . ILE C 1 155 ? 275.853 220.741 245.896 1.00 58.06  ? 155 ILE C O   1 
ATOM   6693  C  CB  . ILE C 1 155 ? 274.206 218.905 243.670 1.00 69.36  ? 155 ILE C CB  1 
ATOM   6694  C  CG1 . ILE C 1 155 ? 273.944 219.248 242.202 1.00 74.23  ? 155 ILE C CG1 1 
ATOM   6695  C  CG2 . ILE C 1 155 ? 273.252 219.663 244.576 1.00 63.19  ? 155 ILE C CG2 1 
ATOM   6696  C  CD1 . ILE C 1 155 ? 272.483 219.216 241.818 1.00 73.58  ? 155 ILE C CD1 1 
ATOM   6697  N  N   . ALA C 1 156 ? 275.869 218.545 246.375 1.00 57.48  ? 156 ALA C N   1 
ATOM   6698  C  CA  . ALA C 1 156 ? 276.050 218.792 247.802 1.00 54.53  ? 156 ALA C CA  1 
ATOM   6699  C  C   . ALA C 1 156 ? 277.375 219.493 248.071 1.00 55.87  ? 156 ALA C C   1 
ATOM   6700  O  O   . ALA C 1 156 ? 277.441 220.449 248.853 1.00 58.05  ? 156 ALA C O   1 
ATOM   6701  C  CB  . ALA C 1 156 ? 275.966 217.477 248.578 1.00 55.54  ? 156 ALA C CB  1 
ATOM   6702  N  N   . ALA C 1 157 ? 278.447 219.032 247.424 1.00 56.88  ? 157 ALA C N   1 
ATOM   6703  C  CA  . ALA C 1 157 ? 279.744 219.677 247.603 1.00 50.97  ? 157 ALA C CA  1 
ATOM   6704  C  C   . ALA C 1 157 ? 279.705 221.127 247.137 1.00 51.57  ? 157 ALA C C   1 
ATOM   6705  O  O   . ALA C 1 157 ? 280.276 222.011 247.786 1.00 50.04  ? 157 ALA C O   1 
ATOM   6706  C  CB  . ALA C 1 157 ? 280.827 218.902 246.855 1.00 50.39  ? 157 ALA C CB  1 
ATOM   6707  N  N   . ILE C 1 158 ? 279.041 221.390 246.010 1.00 49.70  ? 158 ILE C N   1 
ATOM   6708  C  CA  . ILE C 1 158 ? 278.958 222.754 245.497 1.00 43.80  ? 158 ILE C CA  1 
ATOM   6709  C  C   . ILE C 1 158 ? 278.174 223.641 246.455 1.00 46.24  ? 158 ILE C C   1 
ATOM   6710  O  O   . ILE C 1 158 ? 278.564 224.783 246.726 1.00 48.72  ? 158 ILE C O   1 
ATOM   6711  C  CB  . ILE C 1 158 ? 278.337 222.757 244.089 1.00 47.74  ? 158 ILE C CB  1 
ATOM   6712  C  CG1 . ILE C 1 158 ? 279.279 222.085 243.089 1.00 44.73  ? 158 ILE C CG1 1 
ATOM   6713  C  CG2 . ILE C 1 158 ? 278.020 224.176 243.653 1.00 48.12  ? 158 ILE C CG2 1 
ATOM   6714  C  CD1 . ILE C 1 158 ? 278.831 222.210 241.653 1.00 50.27  ? 158 ILE C CD1 1 
ATOM   6715  N  N   . ASN C 1 159 ? 277.056 223.137 246.979 1.00 45.96  ? 159 ASN C N   1 
ATOM   6716  C  CA  . ASN C 1 159 ? 276.212 223.916 247.875 1.00 45.85  ? 159 ASN C CA  1 
ATOM   6717  C  C   . ASN C 1 159 ? 276.785 224.044 249.279 1.00 46.95  ? 159 ASN C C   1 
ATOM   6718  O  O   . ASN C 1 159 ? 276.309 224.887 250.047 1.00 46.60  ? 159 ASN C O   1 
ATOM   6719  C  CB  . ASN C 1 159 ? 274.815 223.294 247.954 1.00 51.20  ? 159 ASN C CB  1 
ATOM   6720  C  CG  . ASN C 1 159 ? 274.074 223.350 246.633 1.00 59.96  ? 159 ASN C CG  1 
ATOM   6721  O  OD1 . ASN C 1 159 ? 274.458 224.084 245.722 1.00 59.65  ? 159 ASN C OD1 1 
ATOM   6722  N  ND2 . ASN C 1 159 ? 273.008 222.567 246.520 1.00 57.03  ? 159 ASN C ND2 1 
ATOM   6723  N  N   . SER C 1 160 ? 277.785 223.234 249.636 1.00 45.27  ? 160 SER C N   1 
ATOM   6724  C  CA  . SER C 1 160 ? 278.339 223.310 250.984 1.00 46.39  ? 160 SER C CA  1 
ATOM   6725  C  C   . SER C 1 160 ? 278.931 224.682 251.283 1.00 44.17  ? 160 SER C C   1 
ATOM   6726  O  O   . SER C 1 160 ? 278.969 225.099 252.446 1.00 46.81  ? 160 SER C O   1 
ATOM   6727  C  CB  . SER C 1 160 ? 279.396 222.223 251.179 1.00 46.65  ? 160 SER C CB  1 
ATOM   6728  O  OG  . SER C 1 160 ? 280.510 222.424 250.328 1.00 47.97  ? 160 SER C OG  1 
ATOM   6729  N  N   . VAL C 1 161 ? 279.394 225.404 250.255 1.00 40.18  ? 161 VAL C N   1 
ATOM   6730  C  CA  . VAL C 1 161 ? 280.001 226.714 250.466 1.00 38.18  ? 161 VAL C CA  1 
ATOM   6731  C  C   . VAL C 1 161 ? 279.006 227.854 250.308 1.00 37.24  ? 161 VAL C C   1 
ATOM   6732  O  O   . VAL C 1 161 ? 279.395 229.024 250.422 1.00 36.81  ? 161 VAL C O   1 
ATOM   6733  C  CB  . VAL C 1 161 ? 281.191 226.930 249.508 1.00 35.51  ? 161 VAL C CB  1 
ATOM   6734  C  CG1 . VAL C 1 161 ? 282.279 225.906 249.781 1.00 39.69  ? 161 VAL C CG1 1 
ATOM   6735  C  CG2 . VAL C 1 161 ? 280.732 226.863 248.064 1.00 34.79  ? 161 VAL C CG2 1 
ATOM   6736  N  N   . TYR C 1 162 ? 277.738 227.555 250.055 1.00 42.53  ? 162 TYR C N   1 
ATOM   6737  C  CA  . TYR C 1 162 ? 276.701 228.565 249.926 1.00 35.83  ? 162 TYR C CA  1 
ATOM   6738  C  C   . TYR C 1 162 ? 275.795 228.553 251.149 1.00 38.62  ? 162 TYR C C   1 
ATOM   6739  O  O   . TYR C 1 162 ? 275.816 227.624 251.962 1.00 44.03  ? 162 TYR C O   1 
ATOM   6740  C  CB  . TYR C 1 162 ? 275.868 228.344 248.660 1.00 32.06  ? 162 TYR C CB  1 
ATOM   6741  C  CG  . TYR C 1 162 ? 276.548 228.779 247.384 1.00 36.61  ? 162 TYR C CG  1 
ATOM   6742  C  CD1 . TYR C 1 162 ? 276.400 230.073 246.905 1.00 35.44  ? 162 TYR C CD1 1 
ATOM   6743  C  CD2 . TYR C 1 162 ? 277.332 227.898 246.656 1.00 39.68  ? 162 TYR C CD2 1 
ATOM   6744  C  CE1 . TYR C 1 162 ? 277.014 230.476 245.737 1.00 33.83  ? 162 TYR C CE1 1 
ATOM   6745  C  CE2 . TYR C 1 162 ? 277.952 228.292 245.487 1.00 35.28  ? 162 TYR C CE2 1 
ATOM   6746  C  CZ  . TYR C 1 162 ? 277.790 229.581 245.032 1.00 35.37  ? 162 TYR C CZ  1 
ATOM   6747  O  OH  . TYR C 1 162 ? 278.405 229.975 243.868 1.00 40.58  ? 162 TYR C OH  1 
ATOM   6748  N  N   . TYR C 1 163 ? 274.992 229.606 251.267 1.00 36.88  ? 163 TYR C N   1 
ATOM   6749  C  CA  . TYR C 1 163 ? 274.062 229.779 252.371 1.00 38.28  ? 163 TYR C CA  1 
ATOM   6750  C  C   . TYR C 1 163 ? 272.832 230.507 251.859 1.00 36.99  ? 163 TYR C C   1 
ATOM   6751  O  O   . TYR C 1 163 ? 272.951 231.529 251.178 1.00 41.86  ? 163 TYR C O   1 
ATOM   6752  C  CB  . TYR C 1 163 ? 274.711 230.561 253.519 1.00 38.33  ? 163 TYR C CB  1 
ATOM   6753  C  CG  . TYR C 1 163 ? 273.730 231.327 254.373 1.00 43.78  ? 163 TYR C CG  1 
ATOM   6754  C  CD1 . TYR C 1 163 ? 272.904 230.677 255.280 1.00 44.48  ? 163 TYR C CD1 1 
ATOM   6755  C  CD2 . TYR C 1 163 ? 273.629 232.706 254.268 1.00 46.50  ? 163 TYR C CD2 1 
ATOM   6756  C  CE1 . TYR C 1 163 ? 272.007 231.383 256.058 1.00 42.18  ? 163 TYR C CE1 1 
ATOM   6757  C  CE2 . TYR C 1 163 ? 272.739 233.417 255.039 1.00 45.80  ? 163 TYR C CE2 1 
ATOM   6758  C  CZ  . TYR C 1 163 ? 271.931 232.754 255.931 1.00 49.10  ? 163 TYR C CZ  1 
ATOM   6759  O  OH  . TYR C 1 163 ? 271.045 233.473 256.697 1.00 54.73  ? 163 TYR C OH  1 
ATOM   6760  N  N   . THR C 1 164 ? 271.657 229.975 252.177 1.00 40.85  ? 164 THR C N   1 
ATOM   6761  C  CA  . THR C 1 164 ? 270.391 230.539 251.736 1.00 42.01  ? 164 THR C CA  1 
ATOM   6762  C  C   . THR C 1 164 ? 269.662 231.137 252.929 1.00 42.89  ? 164 THR C C   1 
ATOM   6763  O  O   . THR C 1 164 ? 269.532 230.487 253.971 1.00 42.98  ? 164 THR C O   1 
ATOM   6764  C  CB  . THR C 1 164 ? 269.518 229.476 251.065 1.00 37.53  ? 164 THR C CB  1 
ATOM   6765  O  OG1 . THR C 1 164 ? 270.301 228.739 250.119 1.00 43.58  ? 164 THR C OG1 1 
ATOM   6766  C  CG2 . THR C 1 164 ? 268.347 230.124 250.345 1.00 37.13  ? 164 THR C CG2 1 
ATOM   6767  N  N   . ASN C 1 165 ? 269.201 232.368 252.778 1.00 41.01  ? 165 ASN C N   1 
ATOM   6768  C  CA  . ASN C 1 165 ? 268.374 232.982 253.805 1.00 40.15  ? 165 ASN C CA  1 
ATOM   6769  C  C   . ASN C 1 165 ? 267.035 232.262 253.855 1.00 42.97  ? 165 ASN C C   1 
ATOM   6770  O  O   . ASN C 1 165 ? 266.338 232.201 252.835 1.00 44.73  ? 165 ASN C O   1 
ATOM   6771  C  CB  . ASN C 1 165 ? 268.177 234.465 253.511 1.00 39.69  ? 165 ASN C CB  1 
ATOM   6772  C  CG  . ASN C 1 165 ? 267.784 235.256 254.740 1.00 40.83  ? 165 ASN C CG  1 
ATOM   6773  O  OD1 . ASN C 1 165 ? 266.703 235.065 255.294 1.00 43.07  ? 165 ASN C OD1 1 
ATOM   6774  N  ND2 . ASN C 1 165 ? 268.661 236.151 255.173 1.00 42.29  ? 165 ASN C ND2 1 
ATOM   6775  N  N   . PRO C 1 166 ? 266.642 231.688 254.994 1.00 39.72  ? 166 PRO C N   1 
ATOM   6776  C  CA  . PRO C 1 166 ? 265.345 230.996 255.045 1.00 40.21  ? 166 PRO C CA  1 
ATOM   6777  C  C   . PRO C 1 166 ? 264.166 231.916 254.791 1.00 40.67  ? 166 PRO C C   1 
ATOM   6778  O  O   . PRO C 1 166 ? 263.111 231.447 254.345 1.00 41.56  ? 166 PRO C O   1 
ATOM   6779  C  CB  . PRO C 1 166 ? 265.317 230.410 256.463 1.00 41.76  ? 166 PRO C CB  1 
ATOM   6780  C  CG  . PRO C 1 166 ? 266.286 231.231 257.241 1.00 42.20  ? 166 PRO C CG  1 
ATOM   6781  C  CD  . PRO C 1 166 ? 267.357 231.635 256.278 1.00 40.15  ? 166 PRO C CD  1 
ATOM   6782  N  N   . VAL C 1 167 ? 264.311 233.212 255.056 1.00 40.34  ? 167 VAL C N   1 
ATOM   6783  C  CA  . VAL C 1 167 ? 263.219 234.164 254.891 1.00 39.40  ? 167 VAL C CA  1 
ATOM   6784  C  C   . VAL C 1 167 ? 263.207 234.698 253.466 1.00 41.76  ? 167 VAL C C   1 
ATOM   6785  O  O   . VAL C 1 167 ? 262.218 234.545 252.742 1.00 44.28  ? 167 VAL C O   1 
ATOM   6786  C  CB  . VAL C 1 167 ? 263.330 235.314 255.907 1.00 37.11  ? 167 VAL C CB  1 
ATOM   6787  C  CG1 . VAL C 1 167 ? 262.244 236.345 255.661 1.00 34.54  ? 167 VAL C CG1 1 
ATOM   6788  C  CG2 . VAL C 1 167 ? 263.249 234.776 257.325 1.00 37.91  ? 167 VAL C CG2 1 
ATOM   6789  N  N   . THR C 1 168 ? 264.304 235.333 253.053 1.00 41.91  ? 168 THR C N   1 
ATOM   6790  C  CA  . THR C 1 168 ? 264.377 235.926 251.725 1.00 40.86  ? 168 THR C CA  1 
ATOM   6791  C  C   . THR C 1 168 ? 264.687 234.910 250.634 1.00 44.05  ? 168 THR C C   1 
ATOM   6792  O  O   . THR C 1 168 ? 264.544 235.235 249.452 1.00 47.01  ? 168 THR C O   1 
ATOM   6793  C  CB  . THR C 1 168 ? 265.428 237.040 251.700 1.00 39.38  ? 168 THR C CB  1 
ATOM   6794  O  OG1 . THR C 1 168 ? 266.725 236.474 251.479 1.00 47.26  ? 168 THR C OG1 1 
ATOM   6795  C  CG2 . THR C 1 168 ? 265.431 237.800 253.015 1.00 35.39  ? 168 THR C CG2 1 
ATOM   6796  N  N   . HIS C 1 169 ? 265.098 233.696 250.999 1.00 45.75  ? 169 HIS C N   1 
ATOM   6797  C  CA  . HIS C 1 169 ? 265.425 232.650 250.032 1.00 44.18  ? 169 HIS C CA  1 
ATOM   6798  C  C   . HIS C 1 169 ? 266.549 233.078 249.093 1.00 47.01  ? 169 HIS C C   1 
ATOM   6799  O  O   . HIS C 1 169 ? 266.594 232.663 247.933 1.00 49.41  ? 169 HIS C O   1 
ATOM   6800  C  CB  . HIS C 1 169 ? 264.190 232.232 249.231 1.00 44.93  ? 169 HIS C CB  1 
ATOM   6801  C  CG  . HIS C 1 169 ? 263.024 231.843 250.084 1.00 48.37  ? 169 HIS C CG  1 
ATOM   6802  N  ND1 . HIS C 1 169 ? 263.099 230.850 251.036 1.00 49.57  ? 169 HIS C ND1 1 
ATOM   6803  C  CD2 . HIS C 1 169 ? 261.756 232.316 250.132 1.00 47.01  ? 169 HIS C CD2 1 
ATOM   6804  C  CE1 . HIS C 1 169 ? 261.927 230.727 251.633 1.00 51.62  ? 169 HIS C CE1 1 
ATOM   6805  N  NE2 . HIS C 1 169 ? 261.095 231.605 251.103 1.00 51.10  ? 169 HIS C NE2 1 
ATOM   6806  N  N   . ASP C 1 170 ? 267.467 233.902 249.587 1.00 46.73  ? 170 ASP C N   1 
ATOM   6807  C  CA  . ASP C 1 170 ? 268.587 234.393 248.797 1.00 46.05  ? 170 ASP C CA  1 
ATOM   6808  C  C   . ASP C 1 170 ? 269.815 233.535 249.064 1.00 46.51  ? 170 ASP C C   1 
ATOM   6809  O  O   . ASP C 1 170 ? 270.181 233.308 250.221 1.00 46.23  ? 170 ASP C O   1 
ATOM   6810  C  CB  . ASP C 1 170 ? 268.881 235.858 249.119 1.00 48.39  ? 170 ASP C CB  1 
ATOM   6811  C  CG  . ASP C 1 170 ? 269.877 236.475 248.159 1.00 62.58  ? 170 ASP C CG  1 
ATOM   6812  O  OD1 . ASP C 1 170 ? 270.067 235.914 247.059 1.00 66.31  ? 170 ASP C OD1 1 
ATOM   6813  O  OD2 . ASP C 1 170 ? 270.471 237.519 248.502 1.00 62.08  ? 170 ASP C OD2 1 
ATOM   6814  N  N   . ARG C 1 171 ? 270.447 233.064 247.992 1.00 46.84  ? 171 ARG C N   1 
ATOM   6815  C  CA  . ARG C 1 171 ? 271.604 232.182 248.077 1.00 43.71  ? 171 ARG C CA  1 
ATOM   6816  C  C   . ARG C 1 171 ? 272.871 232.990 247.825 1.00 46.63  ? 171 ARG C C   1 
ATOM   6817  O  O   . ARG C 1 171 ? 273.062 233.525 246.727 1.00 49.77  ? 171 ARG C O   1 
ATOM   6818  C  CB  . ARG C 1 171 ? 271.480 231.039 247.070 1.00 42.84  ? 171 ARG C CB  1 
ATOM   6819  C  CG  . ARG C 1 171 ? 272.469 229.903 247.266 1.00 42.39  ? 171 ARG C CG  1 
ATOM   6820  C  CD  . ARG C 1 171 ? 272.023 228.674 246.491 1.00 43.59  ? 171 ARG C CD  1 
ATOM   6821  N  NE  . ARG C 1 171 ? 273.116 227.748 246.222 1.00 46.42  ? 171 ARG C NE  1 
ATOM   6822  C  CZ  . ARG C 1 171 ? 273.916 227.820 245.167 1.00 48.03  ? 171 ARG C CZ  1 
ATOM   6823  N  NH1 . ARG C 1 171 ? 273.786 228.780 244.266 1.00 47.21  ? 171 ARG C NH1 1 
ATOM   6824  N  NH2 . ARG C 1 171 ? 274.867 226.905 245.011 1.00 46.50  ? 171 ARG C NH2 1 
ATOM   6825  N  N   . LYS C 1 172 ? 273.732 233.074 248.836 1.00 45.56  ? 172 LYS C N   1 
ATOM   6826  C  CA  . LYS C 1 172 ? 274.980 233.815 248.730 1.00 41.98  ? 172 LYS C CA  1 
ATOM   6827  C  C   . LYS C 1 172 ? 276.107 232.987 249.327 1.00 39.29  ? 172 LYS C C   1 
ATOM   6828  O  O   . LYS C 1 172 ? 275.883 232.105 250.157 1.00 41.86  ? 172 LYS C O   1 
ATOM   6829  C  CB  . LYS C 1 172 ? 274.895 235.175 249.435 1.00 42.58  ? 172 LYS C CB  1 
ATOM   6830  C  CG  . LYS C 1 172 ? 273.780 236.070 248.927 1.00 51.71  ? 172 LYS C CG  1 
ATOM   6831  C  CD  . LYS C 1 172 ? 273.141 236.852 250.064 1.00 57.49  ? 172 LYS C CD  1 
ATOM   6832  C  CE  . LYS C 1 172 ? 273.992 238.046 250.462 1.00 55.08  ? 172 LYS C CE  1 
ATOM   6833  N  NZ  . LYS C 1 172 ? 273.805 238.410 251.894 1.00 52.75  ? 172 LYS C NZ  1 
ATOM   6834  N  N   . LEU C 1 173 ? 277.329 233.279 248.895 1.00 37.07  ? 173 LEU C N   1 
ATOM   6835  C  CA  . LEU C 1 173 ? 278.487 232.583 249.436 1.00 35.34  ? 173 LEU C CA  1 
ATOM   6836  C  C   . LEU C 1 173 ? 278.567 232.791 250.942 1.00 35.93  ? 173 LEU C C   1 
ATOM   6837  O  O   . LEU C 1 173 ? 278.414 233.912 251.435 1.00 37.27  ? 173 LEU C O   1 
ATOM   6838  C  CB  . LEU C 1 173 ? 279.765 233.079 248.764 1.00 33.75  ? 173 LEU C CB  1 
ATOM   6839  C  CG  . LEU C 1 173 ? 280.050 232.534 247.367 1.00 30.21  ? 173 LEU C CG  1 
ATOM   6840  C  CD1 . LEU C 1 173 ? 281.312 233.165 246.806 1.00 26.97  ? 173 LEU C CD1 1 
ATOM   6841  C  CD2 . LEU C 1 173 ? 280.165 231.020 247.396 1.00 26.87  ? 173 LEU C CD2 1 
ATOM   6842  N  N   . ASN C 1 174 ? 278.812 231.712 251.669 1.00 35.42  ? 174 ASN C N   1 
ATOM   6843  C  CA  . ASN C 1 174 ? 278.862 231.792 253.123 1.00 36.46  ? 174 ASN C CA  1 
ATOM   6844  C  C   . ASN C 1 174 ? 280.139 232.500 253.557 1.00 40.50  ? 174 ASN C C   1 
ATOM   6845  O  O   . ASN C 1 174 ? 281.237 232.018 253.253 1.00 41.36  ? 174 ASN C O   1 
ATOM   6846  C  CB  . ASN C 1 174 ? 278.792 230.395 253.730 1.00 37.26  ? 174 ASN C CB  1 
ATOM   6847  C  CG  . ASN C 1 174 ? 278.494 230.419 255.214 1.00 42.53  ? 174 ASN C CG  1 
ATOM   6848  O  OD1 . ASN C 1 174 ? 278.704 231.427 255.886 1.00 45.43  ? 174 ASN C OD1 1 
ATOM   6849  N  ND2 . ASN C 1 174 ? 277.999 229.303 255.734 1.00 43.60  ? 174 ASN C ND2 1 
ATOM   6850  N  N   . PRO C 1 175 ? 280.050 233.633 254.256 1.00 40.44  ? 175 PRO C N   1 
ATOM   6851  C  CA  . PRO C 1 175 ? 281.276 234.323 254.686 1.00 36.11  ? 175 PRO C CA  1 
ATOM   6852  C  C   . PRO C 1 175 ? 282.144 233.488 255.606 1.00 39.91  ? 175 PRO C C   1 
ATOM   6853  O  O   . PRO C 1 175 ? 283.374 233.620 255.574 1.00 40.73  ? 175 PRO C O   1 
ATOM   6854  C  CB  . PRO C 1 175 ? 280.743 235.577 255.395 1.00 37.19  ? 175 PRO C CB  1 
ATOM   6855  C  CG  . PRO C 1 175 ? 279.334 235.731 254.910 1.00 36.00  ? 175 PRO C CG  1 
ATOM   6856  C  CD  . PRO C 1 175 ? 278.836 234.344 254.685 1.00 39.76  ? 175 PRO C CD  1 
ATOM   6857  N  N   . ASP C 1 176 ? 281.541 232.633 256.431 1.00 40.93  ? 176 ASP C N   1 
ATOM   6858  C  CA  . ASP C 1 176 ? 282.297 231.795 257.351 1.00 42.39  ? 176 ASP C CA  1 
ATOM   6859  C  C   . ASP C 1 176 ? 282.972 230.620 256.661 1.00 42.95  ? 176 ASP C C   1 
ATOM   6860  O  O   . ASP C 1 176 ? 283.804 229.952 257.284 1.00 44.26  ? 176 ASP C O   1 
ATOM   6861  C  CB  . ASP C 1 176 ? 281.379 231.285 258.463 1.00 48.35  ? 176 ASP C CB  1 
ATOM   6862  C  CG  . ASP C 1 176 ? 280.457 232.362 258.995 1.00 57.10  ? 176 ASP C CG  1 
ATOM   6863  O  OD1 . ASP C 1 176 ? 279.383 232.575 258.396 1.00 54.83  ? 176 ASP C OD1 1 
ATOM   6864  O  OD2 . ASP C 1 176 ? 280.807 232.998 260.011 1.00 61.92  ? 176 ASP C OD2 1 
ATOM   6865  N  N   . GLN C 1 177 ? 282.634 230.350 255.400 1.00 39.17  ? 177 GLN C N   1 
ATOM   6866  C  CA  . GLN C 1 177 ? 283.294 229.305 254.632 1.00 36.78  ? 177 GLN C CA  1 
ATOM   6867  C  C   . GLN C 1 177 ? 284.374 229.838 253.704 1.00 34.78  ? 177 GLN C C   1 
ATOM   6868  O  O   . GLN C 1 177 ? 285.234 229.063 253.273 1.00 38.64  ? 177 GLN C O   1 
ATOM   6869  C  CB  . GLN C 1 177 ? 282.266 228.525 253.801 1.00 41.67  ? 177 GLN C CB  1 
ATOM   6870  C  CG  . GLN C 1 177 ? 281.185 227.847 254.624 1.00 38.60  ? 177 GLN C CG  1 
ATOM   6871  C  CD  . GLN C 1 177 ? 281.670 226.580 255.294 1.00 44.54  ? 177 GLN C CD  1 
ATOM   6872  O  OE1 . GLN C 1 177 ? 281.952 225.584 254.631 1.00 45.74  ? 177 GLN C OE1 1 
ATOM   6873  N  NE2 . GLN C 1 177 ? 281.773 226.613 256.617 1.00 46.61  ? 177 GLN C NE2 1 
ATOM   6874  N  N   . MET C 1 178 ? 284.354 231.135 253.391 1.00 32.71  ? 178 MET C N   1 
ATOM   6875  C  CA  . MET C 1 178 ? 285.311 231.738 252.464 1.00 29.75  ? 178 MET C CA  1 
ATOM   6876  C  C   . MET C 1 178 ? 286.577 232.134 253.225 1.00 28.02  ? 178 MET C C   1 
ATOM   6877  O  O   . MET C 1 178 ? 286.852 233.305 253.494 1.00 28.24  ? 178 MET C O   1 
ATOM   6878  C  CB  . MET C 1 178 ? 284.687 232.935 251.760 1.00 30.24  ? 178 MET C CB  1 
ATOM   6879  C  CG  . MET C 1 178 ? 283.573 232.585 250.788 1.00 30.21  ? 178 MET C CG  1 
ATOM   6880  S  SD  . MET C 1 178 ? 284.126 231.596 249.389 1.00 39.72  ? 178 MET C SD  1 
ATOM   6881  C  CE  . MET C 1 178 ? 283.743 229.947 249.969 1.00 28.13  ? 178 MET C CE  1 
ATOM   6882  N  N   . VAL C 1 179 ? 287.367 231.120 253.565 1.00 27.30  ? 179 VAL C N   1 
ATOM   6883  C  CA  . VAL C 1 179 ? 288.587 231.295 254.342 1.00 28.46  ? 179 VAL C CA  1 
ATOM   6884  C  C   . VAL C 1 179 ? 289.780 230.906 253.482 1.00 25.17  ? 179 VAL C C   1 
ATOM   6885  O  O   . VAL C 1 179 ? 289.754 229.887 252.785 1.00 30.34  ? 179 VAL C O   1 
ATOM   6886  C  CB  . VAL C 1 179 ? 288.556 230.472 255.646 1.00 29.53  ? 179 VAL C CB  1 
ATOM   6887  C  CG1 . VAL C 1 179 ? 287.383 230.900 256.508 1.00 26.73  ? 179 VAL C CG1 1 
ATOM   6888  C  CG2 . VAL C 1 179 ? 288.472 228.992 255.332 1.00 36.39  ? 179 VAL C CG2 1 
ATOM   6889  N  N   . TYR C 1 180 ? 290.823 231.728 253.535 1.00 24.02  ? 180 TYR C N   1 
ATOM   6890  C  CA  . TYR C 1 180 ? 292.039 231.536 252.757 1.00 24.83  ? 180 TYR C CA  1 
ATOM   6891  C  C   . TYR C 1 180 ? 293.196 231.233 253.698 1.00 23.66  ? 180 TYR C C   1 
ATOM   6892  O  O   . TYR C 1 180 ? 293.373 231.918 254.710 1.00 24.51  ? 180 TYR C O   1 
ATOM   6893  C  CB  . TYR C 1 180 ? 292.343 232.779 251.918 1.00 21.43  ? 180 TYR C CB  1 
ATOM   6894  C  CG  . TYR C 1 180 ? 293.565 232.660 251.039 1.00 21.29  ? 180 TYR C CG  1 
ATOM   6895  C  CD1 . TYR C 1 180 ? 293.634 231.701 250.040 1.00 22.04  ? 180 TYR C CD1 1 
ATOM   6896  C  CD2 . TYR C 1 180 ? 294.644 233.518 251.199 1.00 20.43  ? 180 TYR C CD2 1 
ATOM   6897  C  CE1 . TYR C 1 180 ? 294.744 231.595 249.232 1.00 20.72  ? 180 TYR C CE1 1 
ATOM   6898  C  CE2 . TYR C 1 180 ? 295.758 233.419 250.395 1.00 18.51  ? 180 TYR C CE2 1 
ATOM   6899  C  CZ  . TYR C 1 180 ? 295.803 232.455 249.413 1.00 20.26  ? 180 TYR C CZ  1 
ATOM   6900  O  OH  . TYR C 1 180 ? 296.910 232.348 248.606 1.00 24.26  ? 180 TYR C OH  1 
ATOM   6901  N  N   . ARG C 1 181 ? 293.969 230.204 253.365 1.00 24.32  ? 181 ARG C N   1 
ATOM   6902  C  CA  . ARG C 1 181 ? 295.116 229.776 254.154 1.00 25.98  ? 181 ARG C CA  1 
ATOM   6903  C  C   . ARG C 1 181 ? 296.400 230.132 253.418 1.00 27.19  ? 181 ARG C C   1 
ATOM   6904  O  O   . ARG C 1 181 ? 296.526 229.864 252.219 1.00 28.08  ? 181 ARG C O   1 
ATOM   6905  C  CB  . ARG C 1 181 ? 295.064 228.271 254.423 1.00 29.17  ? 181 ARG C CB  1 
ATOM   6906  C  CG  . ARG C 1 181 ? 296.192 227.759 255.302 1.00 27.19  ? 181 ARG C CG  1 
ATOM   6907  C  CD  . ARG C 1 181 ? 296.705 226.412 254.824 1.00 33.71  ? 181 ARG C CD  1 
ATOM   6908  N  NE  . ARG C 1 181 ? 297.401 226.513 253.547 1.00 46.28  ? 181 ARG C NE  1 
ATOM   6909  C  CZ  . ARG C 1 181 ? 298.686 226.816 253.414 1.00 43.45  ? 181 ARG C CZ  1 
ATOM   6910  N  NH1 . ARG C 1 181 ? 299.455 227.047 254.465 1.00 40.33  ? 181 ARG C NH1 1 
ATOM   6911  N  NH2 . ARG C 1 181 ? 299.211 226.890 252.195 1.00 41.94  ? 181 ARG C NH2 1 
ATOM   6912  N  N   . TYR C 1 182 ? 297.347 230.732 254.135 1.00 28.10  ? 182 TYR C N   1 
ATOM   6913  C  CA  . TYR C 1 182 ? 298.613 231.106 253.522 1.00 26.30  ? 182 TYR C CA  1 
ATOM   6914  C  C   . TYR C 1 182 ? 299.689 231.249 254.588 1.00 24.21  ? 182 TYR C C   1 
ATOM   6915  O  O   . TYR C 1 182 ? 299.405 231.583 255.741 1.00 25.82  ? 182 TYR C O   1 
ATOM   6916  C  CB  . TYR C 1 182 ? 298.481 232.405 252.717 1.00 27.45  ? 182 TYR C CB  1 
ATOM   6917  C  CG  . TYR C 1 182 ? 298.357 233.655 253.558 1.00 25.84  ? 182 TYR C CG  1 
ATOM   6918  C  CD1 . TYR C 1 182 ? 297.163 233.975 254.188 1.00 19.80  ? 182 TYR C CD1 1 
ATOM   6919  C  CD2 . TYR C 1 182 ? 299.431 234.519 253.714 1.00 22.41  ? 182 TYR C CD2 1 
ATOM   6920  C  CE1 . TYR C 1 182 ? 297.044 235.116 254.951 1.00 19.66  ? 182 TYR C CE1 1 
ATOM   6921  C  CE2 . TYR C 1 182 ? 299.321 235.661 254.474 1.00 20.02  ? 182 TYR C CE2 1 
ATOM   6922  C  CZ  . TYR C 1 182 ? 298.126 235.955 255.090 1.00 20.81  ? 182 TYR C CZ  1 
ATOM   6923  O  OH  . TYR C 1 182 ? 298.014 237.094 255.850 1.00 23.49  ? 182 TYR C OH  1 
ATOM   6924  N  N   . GLU C 1 183 ? 300.932 231.012 254.177 1.00 29.29  ? 183 GLU C N   1 
ATOM   6925  C  CA  . GLU C 1 183 ? 302.092 231.145 255.044 1.00 27.91  ? 183 GLU C CA  1 
ATOM   6926  C  C   . GLU C 1 183 ? 303.028 232.214 254.501 1.00 26.64  ? 183 GLU C C   1 
ATOM   6927  O  O   . GLU C 1 183 ? 303.131 232.419 253.288 1.00 31.55  ? 183 GLU C O   1 
ATOM   6928  C  CB  . GLU C 1 183 ? 302.859 229.827 255.175 1.00 30.79  ? 183 GLU C CB  1 
ATOM   6929  C  CG  . GLU C 1 183 ? 301.997 228.591 255.283 1.00 36.29  ? 183 GLU C CG  1 
ATOM   6930  C  CD  . GLU C 1 183 ? 302.769 227.334 254.945 1.00 45.54  ? 183 GLU C CD  1 
ATOM   6931  O  OE1 . GLU C 1 183 ? 303.741 227.432 254.167 1.00 45.24  ? 183 GLU C OE1 1 
ATOM   6932  O  OE2 . GLU C 1 183 ? 302.416 226.254 255.461 1.00 54.07  ? 183 GLU C OE2 1 
ATOM   6933  N  N   . VAL C 1 184 ? 303.706 232.897 255.418 1.00 25.44  ? 184 VAL C N   1 
ATOM   6934  C  CA  . VAL C 1 184 ? 304.684 233.924 255.089 1.00 25.04  ? 184 VAL C CA  1 
ATOM   6935  C  C   . VAL C 1 184 ? 305.945 233.655 255.896 1.00 26.21  ? 184 VAL C C   1 
ATOM   6936  O  O   . VAL C 1 184 ? 305.878 233.441 257.111 1.00 25.08  ? 184 VAL C O   1 
ATOM   6937  C  CB  . VAL C 1 184 ? 304.153 235.340 255.377 1.00 27.18  ? 184 VAL C CB  1 
ATOM   6938  C  CG1 . VAL C 1 184 ? 304.881 236.362 254.520 1.00 26.44  ? 184 VAL C CG1 1 
ATOM   6939  C  CG2 . VAL C 1 184 ? 302.654 235.406 255.148 1.00 27.25  ? 184 VAL C CG2 1 
ATOM   6940  N  N   . TYR C 1 185 ? 307.091 233.663 255.224 1.00 28.12  ? 185 TYR C N   1 
ATOM   6941  C  CA  . TYR C 1 185 ? 308.371 233.483 255.889 1.00 24.25  ? 185 TYR C CA  1 
ATOM   6942  C  C   . TYR C 1 185 ? 308.948 234.845 256.250 1.00 26.71  ? 185 TYR C C   1 
ATOM   6943  O  O   . TYR C 1 185 ? 309.011 235.742 255.403 1.00 30.41  ? 185 TYR C O   1 
ATOM   6944  C  CB  . TYR C 1 185 ? 309.337 232.706 254.997 1.00 22.64  ? 185 TYR C CB  1 
ATOM   6945  C  CG  . TYR C 1 185 ? 310.596 232.268 255.701 1.00 27.10  ? 185 TYR C CG  1 
ATOM   6946  C  CD1 . TYR C 1 185 ? 310.599 231.151 256.523 1.00 28.30  ? 185 TYR C CD1 1 
ATOM   6947  C  CD2 . TYR C 1 185 ? 311.782 232.970 255.546 1.00 27.17  ? 185 TYR C CD2 1 
ATOM   6948  C  CE1 . TYR C 1 185 ? 311.745 230.746 257.170 1.00 27.99  ? 185 TYR C CE1 1 
ATOM   6949  C  CE2 . TYR C 1 185 ? 312.931 232.574 256.189 1.00 27.06  ? 185 TYR C CE2 1 
ATOM   6950  C  CZ  . TYR C 1 185 ? 312.909 231.460 256.998 1.00 32.63  ? 185 TYR C CZ  1 
ATOM   6951  O  OH  . TYR C 1 185 ? 314.057 231.063 257.639 1.00 39.71  ? 185 TYR C OH  1 
ATOM   6952  N  N   . ASP C 1 186 ? 309.359 234.999 257.508 1.00 26.63  ? 186 ASP C N   1 
ATOM   6953  C  CA  . ASP C 1 186 ? 309.914 236.258 258.004 1.00 26.36  ? 186 ASP C CA  1 
ATOM   6954  C  C   . ASP C 1 186 ? 311.405 236.272 257.700 1.00 26.73  ? 186 ASP C C   1 
ATOM   6955  O  O   . ASP C 1 186 ? 312.232 235.849 258.508 1.00 28.78  ? 186 ASP C O   1 
ATOM   6956  C  CB  . ASP C 1 186 ? 309.642 236.421 259.494 1.00 28.48  ? 186 ASP C CB  1 
ATOM   6957  C  CG  . ASP C 1 186 ? 309.677 237.871 259.941 1.00 34.73  ? 186 ASP C CG  1 
ATOM   6958  O  OD1 . ASP C 1 186 ? 310.133 238.729 259.158 1.00 34.91  ? 186 ASP C OD1 1 
ATOM   6959  O  OD2 . ASP C 1 186 ? 309.248 238.153 261.078 1.00 36.16  ? 186 ASP C OD2 1 
ATOM   6960  N  N   . TYR C 1 187 ? 311.752 236.760 256.510 1.00 25.53  ? 187 TYR C N   1 
ATOM   6961  C  CA  . TYR C 1 187 ? 313.157 236.844 256.129 1.00 24.09  ? 187 TYR C CA  1 
ATOM   6962  C  C   . TYR C 1 187 ? 313.916 237.820 257.020 1.00 24.93  ? 187 TYR C C   1 
ATOM   6963  O  O   . TYR C 1 187 ? 315.056 237.552 257.417 1.00 33.63  ? 187 TYR C O   1 
ATOM   6964  C  CB  . TYR C 1 187 ? 313.277 237.256 254.663 1.00 26.66  ? 187 TYR C CB  1 
ATOM   6965  C  CG  . TYR C 1 187 ? 312.912 236.171 253.679 1.00 28.50  ? 187 TYR C CG  1 
ATOM   6966  C  CD1 . TYR C 1 187 ? 313.844 235.221 253.286 1.00 26.62  ? 187 TYR C CD1 1 
ATOM   6967  C  CD2 . TYR C 1 187 ? 311.637 236.100 253.136 1.00 28.62  ? 187 TYR C CD2 1 
ATOM   6968  C  CE1 . TYR C 1 187 ? 313.516 234.231 252.383 1.00 28.83  ? 187 TYR C CE1 1 
ATOM   6969  C  CE2 . TYR C 1 187 ? 311.300 235.113 252.233 1.00 23.88  ? 187 TYR C CE2 1 
ATOM   6970  C  CZ  . TYR C 1 187 ? 312.242 234.181 251.860 1.00 31.58  ? 187 TYR C CZ  1 
ATOM   6971  O  OH  . TYR C 1 187 ? 311.909 233.197 250.960 1.00 39.73  ? 187 TYR C OH  1 
ATOM   6972  N  N   . ARG C 1 188 ? 313.304 238.961 257.339 1.00 22.87  ? 188 ARG C N   1 
ATOM   6973  C  CA  . ARG C 1 188 ? 314.002 239.978 258.118 1.00 21.10  ? 188 ARG C CA  1 
ATOM   6974  C  C   . ARG C 1 188 ? 314.300 239.490 259.530 1.00 27.83  ? 188 ARG C C   1 
ATOM   6975  O  O   . ARG C 1 188 ? 315.390 239.732 260.059 1.00 29.00  ? 188 ARG C O   1 
ATOM   6976  C  CB  . ARG C 1 188 ? 313.182 241.265 258.155 1.00 22.10  ? 188 ARG C CB  1 
ATOM   6977  C  CG  . ARG C 1 188 ? 314.023 242.511 258.330 1.00 26.94  ? 188 ARG C CG  1 
ATOM   6978  C  CD  . ARG C 1 188 ? 313.262 243.612 259.043 1.00 31.94  ? 188 ARG C CD  1 
ATOM   6979  N  NE  . ARG C 1 188 ? 314.159 244.645 259.548 1.00 48.66  ? 188 ARG C NE  1 
ATOM   6980  C  CZ  . ARG C 1 188 ? 314.964 245.377 258.789 1.00 40.74  ? 188 ARG C CZ  1 
ATOM   6981  N  NH1 . ARG C 1 188 ? 315.011 245.219 257.477 1.00 34.30  ? 188 ARG C NH1 1 
ATOM   6982  N  NH2 . ARG C 1 188 ? 315.743 246.290 259.362 1.00 35.49  ? 188 ARG C NH2 1 
ATOM   6983  N  N   . SER C 1 189 ? 313.341 238.808 260.159 1.00 27.56  ? 189 SER C N   1 
ATOM   6984  C  CA  . SER C 1 189 ? 313.572 238.282 261.499 1.00 22.89  ? 189 SER C CA  1 
ATOM   6985  C  C   . SER C 1 189 ? 314.613 237.171 261.483 1.00 28.05  ? 189 SER C C   1 
ATOM   6986  O  O   . SER C 1 189 ? 315.420 237.053 262.412 1.00 33.45  ? 189 SER C O   1 
ATOM   6987  C  CB  . SER C 1 189 ? 312.258 237.785 262.098 1.00 28.05  ? 189 SER C CB  1 
ATOM   6988  O  OG  . SER C 1 189 ? 312.412 237.460 263.467 1.00 36.35  ? 189 SER C OG  1 
ATOM   6989  N  N   . ALA C 1 190 ? 314.613 236.347 260.435 1.00 25.06  ? 190 ALA C N   1 
ATOM   6990  C  CA  . ALA C 1 190 ? 315.620 235.300 260.323 1.00 25.51  ? 190 ALA C CA  1 
ATOM   6991  C  C   . ALA C 1 190 ? 317.006 235.879 260.077 1.00 28.92  ? 190 ALA C C   1 
ATOM   6992  O  O   . ALA C 1 190 ? 318.009 235.264 260.454 1.00 30.84  ? 190 ALA C O   1 
ATOM   6993  C  CB  . ALA C 1 190 ? 315.244 234.327 259.208 1.00 23.69  ? 190 ALA C CB  1 
ATOM   6994  N  N   . ALA C 1 191 ? 317.084 237.054 259.451 1.00 30.60  ? 191 ALA C N   1 
ATOM   6995  C  CA  . ALA C 1 191 ? 318.366 237.694 259.187 1.00 25.88  ? 191 ALA C CA  1 
ATOM   6996  C  C   . ALA C 1 191 ? 318.922 238.444 260.390 1.00 26.70  ? 191 ALA C C   1 
ATOM   6997  O  O   . ALA C 1 191 ? 320.097 238.824 260.368 1.00 33.79  ? 191 ALA C O   1 
ATOM   6998  C  CB  . ALA C 1 191 ? 318.239 238.654 258.002 1.00 20.81  ? 191 ALA C CB  1 
ATOM   6999  N  N   . LEU C 1 192 ? 318.121 238.664 261.429 1.00 26.79  ? 192 LEU C N   1 
ATOM   7000  C  CA  . LEU C 1 192 ? 318.596 239.397 262.594 1.00 24.13  ? 192 LEU C CA  1 
ATOM   7001  C  C   . LEU C 1 192 ? 319.756 238.664 263.255 1.00 29.06  ? 192 LEU C C   1 
ATOM   7002  O  O   . LEU C 1 192 ? 319.766 237.434 263.345 1.00 33.97  ? 192 LEU C O   1 
ATOM   7003  C  CB  . LEU C 1 192 ? 317.456 239.593 263.593 1.00 29.51  ? 192 LEU C CB  1 
ATOM   7004  C  CG  . LEU C 1 192 ? 316.511 240.761 263.317 1.00 31.35  ? 192 LEU C CG  1 
ATOM   7005  C  CD1 . LEU C 1 192 ? 315.285 240.684 264.211 1.00 29.93  ? 192 LEU C CD1 1 
ATOM   7006  C  CD2 . LEU C 1 192 ? 317.233 242.084 263.506 1.00 28.44  ? 192 LEU C CD2 1 
ATOM   7007  N  N   . ARG C 1 193 ? 320.742 239.432 263.721 1.00 33.88  ? 193 ARG C N   1 
ATOM   7008  C  CA  . ARG C 1 193 ? 321.926 238.827 264.322 1.00 29.59  ? 193 ARG C CA  1 
ATOM   7009  C  C   . ARG C 1 193 ? 321.579 238.096 265.613 1.00 32.84  ? 193 ARG C C   1 
ATOM   7010  O  O   . ARG C 1 193 ? 322.166 237.052 265.919 1.00 36.13  ? 193 ARG C O   1 
ATOM   7011  C  CB  . ARG C 1 193 ? 322.989 239.896 264.569 1.00 26.23  ? 193 ARG C CB  1 
ATOM   7012  C  CG  . ARG C 1 193 ? 324.075 239.488 265.544 1.00 31.83  ? 193 ARG C CG  1 
ATOM   7013  C  CD  . ARG C 1 193 ? 325.129 238.634 264.866 1.00 32.52  ? 193 ARG C CD  1 
ATOM   7014  N  NE  . ARG C 1 193 ? 325.538 239.185 263.581 1.00 30.70  ? 193 ARG C NE  1 
ATOM   7015  C  CZ  . ARG C 1 193 ? 326.176 238.500 262.642 1.00 34.95  ? 193 ARG C CZ  1 
ATOM   7016  N  NH1 . ARG C 1 193 ? 326.488 237.226 262.809 1.00 37.68  ? 193 ARG C NH1 1 
ATOM   7017  N  NH2 . ARG C 1 193 ? 326.505 239.107 261.507 1.00 32.63  ? 193 ARG C NH2 1 
ATOM   7018  N  N   . GLU C 1 194 ? 320.628 238.627 266.383 1.00 34.31  ? 194 GLU C N   1 
ATOM   7019  C  CA  . GLU C 1 194 ? 320.189 237.977 267.610 1.00 33.30  ? 194 GLU C CA  1 
ATOM   7020  C  C   . GLU C 1 194 ? 319.463 236.663 267.356 1.00 34.36  ? 194 GLU C C   1 
ATOM   7021  O  O   . GLU C 1 194 ? 319.279 235.887 268.299 1.00 37.26  ? 194 GLU C O   1 
ATOM   7022  C  CB  . GLU C 1 194 ? 319.278 238.914 268.404 1.00 35.93  ? 194 GLU C CB  1 
ATOM   7023  C  CG  . GLU C 1 194 ? 319.987 240.107 269.025 1.00 40.39  ? 194 GLU C CG  1 
ATOM   7024  C  CD  . GLU C 1 194 ? 320.366 241.167 268.008 1.00 47.74  ? 194 GLU C CD  1 
ATOM   7025  O  OE1 . GLU C 1 194 ? 319.641 241.319 267.002 1.00 45.42  ? 194 GLU C OE1 1 
ATOM   7026  O  OE2 . GLU C 1 194 ? 321.389 241.852 268.218 1.00 47.87  ? 194 GLU C OE2 1 
ATOM   7027  N  N   . HIS C 1 195 ? 319.048 236.396 266.117 1.00 35.79  ? 195 HIS C N   1 
ATOM   7028  C  CA  . HIS C 1 195 ? 318.275 235.207 265.786 1.00 31.63  ? 195 HIS C CA  1 
ATOM   7029  C  C   . HIS C 1 195 ? 319.093 234.174 265.020 1.00 32.08  ? 195 HIS C C   1 
ATOM   7030  O  O   . HIS C 1 195 ? 318.520 233.273 264.401 1.00 35.77  ? 195 HIS C O   1 
ATOM   7031  C  CB  . HIS C 1 195 ? 317.029 235.590 264.989 1.00 29.94  ? 195 HIS C CB  1 
ATOM   7032  C  CG  . HIS C 1 195 ? 315.994 236.307 265.797 1.00 30.78  ? 195 HIS C CG  1 
ATOM   7033  N  ND1 . HIS C 1 195 ? 314.938 236.981 265.224 1.00 28.85  ? 195 HIS C ND1 1 
ATOM   7034  C  CD2 . HIS C 1 195 ? 315.853 236.453 267.135 1.00 32.41  ? 195 HIS C CD2 1 
ATOM   7035  C  CE1 . HIS C 1 195 ? 314.191 237.513 266.174 1.00 30.03  ? 195 HIS C CE1 1 
ATOM   7036  N  NE2 . HIS C 1 195 ? 314.724 237.207 267.343 1.00 31.49  ? 195 HIS C NE2 1 
ATOM   7037  N  N   . GLN C 1 196 ? 320.418 234.287 265.045 1.00 36.58  ? 196 GLN C N   1 
ATOM   7038  C  CA  . GLN C 1 196 ? 321.259 233.285 264.407 1.00 37.59  ? 196 GLN C CA  1 
ATOM   7039  C  C   . GLN C 1 196 ? 321.012 231.921 265.037 1.00 41.37  ? 196 GLN C C   1 
ATOM   7040  O  O   . GLN C 1 196 ? 320.973 231.788 266.262 1.00 43.40  ? 196 GLN C O   1 
ATOM   7041  C  CB  . GLN C 1 196 ? 322.732 233.672 264.535 1.00 40.56  ? 196 GLN C CB  1 
ATOM   7042  C  CG  . GLN C 1 196 ? 323.199 234.693 263.514 1.00 42.93  ? 196 GLN C CG  1 
ATOM   7043  C  CD  . GLN C 1 196 ? 323.564 234.061 262.187 1.00 54.31  ? 196 GLN C CD  1 
ATOM   7044  O  OE1 . GLN C 1 196 ? 323.239 232.903 261.929 1.00 58.87  ? 196 GLN C OE1 1 
ATOM   7045  N  NE2 . GLN C 1 196 ? 324.248 234.819 261.337 1.00 48.60  ? 196 GLN C NE2 1 
ATOM   7046  N  N   . LEU C 1 197 ? 320.843 230.903 264.193 1.00 41.54  ? 197 LEU C N   1 
ATOM   7047  C  CA  . LEU C 1 197 ? 320.544 229.571 264.705 1.00 42.77  ? 197 LEU C CA  1 
ATOM   7048  C  C   . LEU C 1 197 ? 321.689 229.001 265.529 1.00 43.24  ? 197 LEU C C   1 
ATOM   7049  O  O   . LEU C 1 197 ? 321.465 228.094 266.336 1.00 47.65  ? 197 LEU C O   1 
ATOM   7050  C  CB  . LEU C 1 197 ? 320.202 228.627 263.552 1.00 47.61  ? 197 LEU C CB  1 
ATOM   7051  C  CG  . LEU C 1 197 ? 318.819 228.825 262.928 1.00 39.89  ? 197 LEU C CG  1 
ATOM   7052  C  CD1 . LEU C 1 197 ? 318.496 227.702 261.958 1.00 39.74  ? 197 LEU C CD1 1 
ATOM   7053  C  CD2 . LEU C 1 197 ? 317.761 228.919 264.010 1.00 35.98  ? 197 LEU C CD2 1 
ATOM   7054  N  N   . LYS C 1 198 ? 322.905 229.507 265.346 1.00 48.47  ? 198 LYS C N   1 
ATOM   7055  C  CA  . LYS C 1 198 ? 324.054 229.108 266.145 1.00 45.61  ? 198 LYS C CA  1 
ATOM   7056  C  C   . LYS C 1 198 ? 324.345 230.190 267.175 1.00 48.06  ? 198 LYS C C   1 
ATOM   7057  O  O   . LYS C 1 198 ? 324.422 231.374 266.833 1.00 51.49  ? 198 LYS C O   1 
ATOM   7058  C  CB  . LYS C 1 198 ? 325.281 228.872 265.264 1.00 47.51  ? 198 LYS C CB  1 
ATOM   7059  C  CG  . LYS C 1 198 ? 325.268 227.549 264.520 1.00 55.09  ? 198 LYS C CG  1 
ATOM   7060  C  CD  . LYS C 1 198 ? 326.473 227.420 263.604 1.00 62.21  ? 198 LYS C CD  1 
ATOM   7061  C  CE  . LYS C 1 198 ? 326.656 225.989 263.130 1.00 72.03  ? 198 LYS C CE  1 
ATOM   7062  N  NZ  . LYS C 1 198 ? 325.358 225.263 263.051 1.00 71.23  ? 198 LYS C NZ  1 
ATOM   7063  N  N   . ALA C 1 199 ? 324.504 229.781 268.434 1.00 45.19  ? 199 ALA C N   1 
ATOM   7064  C  CA  . ALA C 1 199 ? 324.721 230.752 269.500 1.00 44.41  ? 199 ALA C CA  1 
ATOM   7065  C  C   . ALA C 1 199 ? 326.036 231.498 269.327 1.00 49.94  ? 199 ALA C C   1 
ATOM   7066  O  O   . ALA C 1 199 ? 326.140 232.670 269.704 1.00 49.67  ? 199 ALA C O   1 
ATOM   7067  C  CB  . ALA C 1 199 ? 324.679 230.057 270.860 1.00 47.37  ? 199 ALA C CB  1 
ATOM   7068  N  N   . ALA C 1 200 ? 327.051 230.841 268.762 1.00 50.36  ? 200 ALA C N   1 
ATOM   7069  C  CA  . ALA C 1 200 ? 328.355 231.472 268.611 1.00 48.99  ? 200 ALA C CA  1 
ATOM   7070  C  C   . ALA C 1 200 ? 328.332 232.640 267.636 1.00 50.76  ? 200 ALA C C   1 
ATOM   7071  O  O   . ALA C 1 200 ? 329.226 233.491 267.689 1.00 54.01  ? 200 ALA C O   1 
ATOM   7072  C  CB  . ALA C 1 200 ? 329.388 230.442 268.156 1.00 46.92  ? 200 ALA C CB  1 
ATOM   7073  N  N   . LYS C 1 201 ? 327.342 232.701 266.748 1.00 47.58  ? 201 LYS C N   1 
ATOM   7074  C  CA  . LYS C 1 201 ? 327.285 233.723 265.714 1.00 47.08  ? 201 LYS C CA  1 
ATOM   7075  C  C   . LYS C 1 201 ? 326.370 234.885 266.076 1.00 46.17  ? 201 LYS C C   1 
ATOM   7076  O  O   . LYS C 1 201 ? 326.136 235.757 265.236 1.00 45.25  ? 201 LYS C O   1 
ATOM   7077  C  CB  . LYS C 1 201 ? 326.837 233.103 264.389 1.00 45.73  ? 201 LYS C CB  1 
ATOM   7078  C  CG  . LYS C 1 201 ? 327.567 231.823 264.028 1.00 47.24  ? 201 LYS C CG  1 
ATOM   7079  C  CD  . LYS C 1 201 ? 327.338 231.444 262.573 1.00 54.55  ? 201 LYS C CD  1 
ATOM   7080  C  CE  . LYS C 1 201 ? 328.070 232.383 261.628 1.00 61.31  ? 201 LYS C CE  1 
ATOM   7081  N  NZ  . LYS C 1 201 ? 327.336 233.661 261.431 1.00 61.49  ? 201 LYS C NZ  1 
ATOM   7082  N  N   . ARG C 1 202 ? 325.847 234.917 267.299 1.00 44.04  ? 202 ARG C N   1 
ATOM   7083  C  CA  . ARG C 1 202 ? 324.959 235.991 267.720 1.00 36.97  ? 202 ARG C CA  1 
ATOM   7084  C  C   . ARG C 1 202 ? 325.696 237.171 268.337 1.00 39.56  ? 202 ARG C C   1 
ATOM   7085  O  O   . ARG C 1 202 ? 325.062 238.188 268.635 1.00 41.79  ? 202 ARG C O   1 
ATOM   7086  C  CB  . ARG C 1 202 ? 323.923 235.460 268.714 1.00 34.91  ? 202 ARG C CB  1 
ATOM   7087  C  CG  . ARG C 1 202 ? 323.103 234.304 268.180 1.00 36.66  ? 202 ARG C CG  1 
ATOM   7088  C  CD  . ARG C 1 202 ? 322.142 233.774 269.224 1.00 38.84  ? 202 ARG C CD  1 
ATOM   7089  N  NE  . ARG C 1 202 ? 321.572 232.493 268.828 1.00 37.71  ? 202 ARG C NE  1 
ATOM   7090  C  CZ  . ARG C 1 202 ? 321.126 231.576 269.676 1.00 38.62  ? 202 ARG C CZ  1 
ATOM   7091  N  NH1 . ARG C 1 202 ? 321.166 231.767 270.984 1.00 39.27  ? 202 ARG C NH1 1 
ATOM   7092  N  NH2 . ARG C 1 202 ? 320.628 230.440 269.199 1.00 40.02  ? 202 ARG C NH2 1 
ATOM   7093  N  N   . ASN C 1 203 ? 327.007 237.065 268.534 1.00 43.53  ? 203 ASN C N   1 
ATOM   7094  C  CA  . ASN C 1 203 ? 327.794 238.167 269.074 1.00 40.49  ? 203 ASN C CA  1 
ATOM   7095  C  C   . ASN C 1 203 ? 329.180 238.111 268.455 1.00 44.37  ? 203 ASN C C   1 
ATOM   7096  O  O   . ASN C 1 203 ? 329.917 237.145 268.673 1.00 47.80  ? 203 ASN C O   1 
ATOM   7097  C  CB  . ASN C 1 203 ? 327.880 238.092 270.598 1.00 45.86  ? 203 ASN C CB  1 
ATOM   7098  C  CG  . ASN C 1 203 ? 327.843 239.460 271.252 1.00 53.70  ? 203 ASN C CG  1 
ATOM   7099  O  OD1 . ASN C 1 203 ? 328.376 240.432 270.717 1.00 56.28  ? 203 ASN C OD1 1 
ATOM   7100  N  ND2 . ASN C 1 203 ? 327.208 239.542 272.415 1.00 57.15  ? 203 ASN C ND2 1 
ATOM   7101  N  N   . LEU C 1 204 ? 329.531 239.139 267.687 1.00 41.53  ? 204 LEU C N   1 
ATOM   7102  C  CA  . LEU C 1 204 ? 330.839 239.208 267.054 1.00 37.13  ? 204 LEU C CA  1 
ATOM   7103  C  C   . LEU C 1 204 ? 331.905 239.812 267.956 1.00 40.66  ? 204 LEU C C   1 
ATOM   7104  O  O   . LEU C 1 204 ? 333.078 239.838 267.571 1.00 48.58  ? 204 LEU C O   1 
ATOM   7105  C  CB  . LEU C 1 204 ? 330.753 240.007 265.748 1.00 35.35  ? 204 LEU C CB  1 
ATOM   7106  C  CG  . LEU C 1 204 ? 329.800 239.445 264.691 1.00 37.65  ? 204 LEU C CG  1 
ATOM   7107  C  CD1 . LEU C 1 204 ? 329.880 240.249 263.406 1.00 34.49  ? 204 LEU C CD1 1 
ATOM   7108  C  CD2 . LEU C 1 204 ? 330.099 237.979 264.428 1.00 34.72  ? 204 LEU C CD2 1 
ATOM   7109  N  N   . ASN C 1 205 ? 331.531 240.291 269.140 1.00 43.24  ? 205 ASN C N   1 
ATOM   7110  C  CA  . ASN C 1 205 ? 332.498 240.806 270.100 1.00 42.59  ? 205 ASN C CA  1 
ATOM   7111  C  C   . ASN C 1 205 ? 333.210 239.632 270.763 1.00 43.78  ? 205 ASN C C   1 
ATOM   7112  O  O   . ASN C 1 205 ? 332.571 238.805 271.422 1.00 51.94  ? 205 ASN C O   1 
ATOM   7113  C  CB  . ASN C 1 205 ? 331.795 241.683 271.135 1.00 39.85  ? 205 ASN C CB  1 
ATOM   7114  C  CG  . ASN C 1 205 ? 332.759 242.344 272.101 1.00 47.83  ? 205 ASN C CG  1 
ATOM   7115  O  OD1 . ASN C 1 205 ? 333.803 241.788 272.436 1.00 53.46  ? 205 ASN C OD1 1 
ATOM   7116  N  ND2 . ASN C 1 205 ? 332.410 243.541 272.554 1.00 43.25  ? 205 ASN C ND2 1 
ATOM   7117  N  N   . THR C 1 206 ? 334.531 239.556 270.588 1.00 43.11  ? 206 THR C N   1 
ATOM   7118  C  CA  . THR C 1 206 ? 335.287 238.431 271.128 1.00 47.83  ? 206 THR C CA  1 
ATOM   7119  C  C   . THR C 1 206 ? 335.437 238.501 272.642 1.00 51.55  ? 206 THR C C   1 
ATOM   7120  O  O   . THR C 1 206 ? 335.685 237.469 273.274 1.00 53.48  ? 206 THR C O   1 
ATOM   7121  C  CB  . THR C 1 206 ? 336.670 238.356 270.477 1.00 46.72  ? 206 THR C CB  1 
ATOM   7122  O  OG1 . THR C 1 206 ? 337.388 239.570 270.728 1.00 53.70  ? 206 THR C OG1 1 
ATOM   7123  C  CG2 . THR C 1 206 ? 336.545 238.145 268.978 1.00 42.05  ? 206 THR C CG2 1 
ATOM   7124  N  N   . ASP C 1 207 ? 335.294 239.687 273.235 1.00 52.85  ? 207 ASP C N   1 
ATOM   7125  C  CA  . ASP C 1 207 ? 335.372 239.813 274.685 1.00 56.77  ? 207 ASP C CA  1 
ATOM   7126  C  C   . ASP C 1 207 ? 334.252 239.064 275.393 1.00 61.24  ? 207 ASP C C   1 
ATOM   7127  O  O   . ASP C 1 207 ? 334.400 238.723 276.571 1.00 64.80  ? 207 ASP C O   1 
ATOM   7128  C  CB  . ASP C 1 207 ? 335.334 241.287 275.087 1.00 55.32  ? 207 ASP C CB  1 
ATOM   7129  C  CG  . ASP C 1 207 ? 336.644 241.997 274.829 1.00 60.95  ? 207 ASP C CG  1 
ATOM   7130  O  OD1 . ASP C 1 207 ? 337.665 241.309 274.624 1.00 63.74  ? 207 ASP C OD1 1 
ATOM   7131  O  OD2 . ASP C 1 207 ? 336.654 243.246 274.832 1.00 61.57  ? 207 ASP C OD2 1 
ATOM   7132  N  N   . ILE C 1 208 ? 333.143 238.803 274.709 1.00 60.49  ? 208 ILE C N   1 
ATOM   7133  C  CA  . ILE C 1 208 ? 331.961 238.198 275.312 1.00 60.80  ? 208 ILE C CA  1 
ATOM   7134  C  C   . ILE C 1 208 ? 331.938 236.716 274.973 1.00 64.09  ? 208 ILE C C   1 
ATOM   7135  O  O   . ILE C 1 208 ? 332.113 236.332 273.809 1.00 64.27  ? 208 ILE C O   1 
ATOM   7136  C  CB  . ILE C 1 208 ? 330.676 238.893 274.831 1.00 59.37  ? 208 ILE C CB  1 
ATOM   7137  C  CG1 . ILE C 1 208 ? 330.429 240.169 275.636 1.00 58.30  ? 208 ILE C CG1 1 
ATOM   7138  C  CG2 . ILE C 1 208 ? 329.487 237.953 274.942 1.00 59.82  ? 208 ILE C CG2 1 
ATOM   7139  C  CD1 . ILE C 1 208 ? 329.880 241.310 274.814 1.00 58.13  ? 208 ILE C CD1 1 
ATOM   7140  N  N   . LYS C 1 209 ? 331.725 235.882 275.986 1.00 69.58  ? 209 LYS C N   1 
ATOM   7141  C  CA  . LYS C 1 209 ? 331.642 234.439 275.815 1.00 75.36  ? 209 LYS C CA  1 
ATOM   7142  C  C   . LYS C 1 209 ? 330.182 234.010 275.757 1.00 78.25  ? 209 LYS C C   1 
ATOM   7143  O  O   . LYS C 1 209 ? 329.360 234.455 276.563 1.00 78.08  ? 209 LYS C O   1 
ATOM   7144  C  CB  . LYS C 1 209 ? 332.359 233.711 276.952 1.00 73.86  ? 209 LYS C CB  1 
ATOM   7145  C  CG  . LYS C 1 209 ? 333.814 234.115 277.121 1.00 75.21  ? 209 LYS C CG  1 
ATOM   7146  C  CD  . LYS C 1 209 ? 334.587 233.956 275.822 1.00 73.96  ? 209 LYS C CD  1 
ATOM   7147  C  CE  . LYS C 1 209 ? 335.915 234.692 275.880 1.00 72.93  ? 209 LYS C CE  1 
ATOM   7148  N  NZ  . LYS C 1 209 ? 337.069 233.752 275.893 1.00 76.17  ? 209 LYS C NZ  1 
ATOM   7149  N  N   . VAL C 1 210 ? 329.870 233.141 274.799 1.00 80.33  ? 210 VAL C N   1 
ATOM   7150  C  CA  . VAL C 1 210 ? 328.491 232.727 274.551 1.00 88.04  ? 210 VAL C CA  1 
ATOM   7151  C  C   . VAL C 1 210 ? 328.038 231.830 275.699 1.00 92.29  ? 210 VAL C C   1 
ATOM   7152  O  O   . VAL C 1 210 ? 328.588 230.745 275.907 1.00 92.84  ? 210 VAL C O   1 
ATOM   7153  C  CB  . VAL C 1 210 ? 328.356 232.013 273.202 1.00 82.81  ? 210 VAL C CB  1 
ATOM   7154  C  CG1 . VAL C 1 210 ? 326.939 231.498 273.017 1.00 78.39  ? 210 VAL C CG1 1 
ATOM   7155  C  CG2 . VAL C 1 210 ? 328.739 232.950 272.068 1.00 76.57  ? 210 VAL C CG2 1 
ATOM   7156  N  N   . ASP C 1 211 ? 327.034 232.279 276.444 1.00 93.12  ? 211 ASP C N   1 
ATOM   7157  C  CA  . ASP C 1 211 ? 326.479 231.459 277.508 1.00 100.59 ? 211 ASP C CA  1 
ATOM   7158  C  C   . ASP C 1 211 ? 325.800 230.227 276.915 1.00 103.81 ? 211 ASP C C   1 
ATOM   7159  O  O   . ASP C 1 211 ? 325.020 230.346 275.962 1.00 101.34 ? 211 ASP C O   1 
ATOM   7160  C  CB  . ASP C 1 211 ? 325.474 232.259 278.337 1.00 104.93 ? 211 ASP C CB  1 
ATOM   7161  C  CG  . ASP C 1 211 ? 326.070 232.787 279.626 1.00 109.49 ? 211 ASP C CG  1 
ATOM   7162  O  OD1 . ASP C 1 211 ? 327.260 233.166 279.622 1.00 108.43 ? 211 ASP C OD1 1 
ATOM   7163  O  OD2 . ASP C 1 211 ? 325.347 232.824 280.644 1.00 108.60 ? 211 ASP C OD2 1 
ATOM   7164  N  N   . PRO C 1 212 ? 326.073 229.031 277.443 1.00 109.62 ? 212 PRO C N   1 
ATOM   7165  C  CA  . PRO C 1 212 ? 325.346 227.850 276.949 1.00 109.97 ? 212 PRO C CA  1 
ATOM   7166  C  C   . PRO C 1 212 ? 323.883 227.852 277.349 1.00 107.12 ? 212 PRO C C   1 
ATOM   7167  O  O   . PRO C 1 212 ? 323.033 227.388 276.578 1.00 102.75 ? 212 PRO C O   1 
ATOM   7168  C  CB  . PRO C 1 212 ? 326.111 226.673 277.577 1.00 108.43 ? 212 PRO C CB  1 
ATOM   7169  C  CG  . PRO C 1 212 ? 327.398 227.257 278.098 1.00 105.74 ? 212 PRO C CG  1 
ATOM   7170  C  CD  . PRO C 1 212 ? 327.099 228.678 278.434 1.00 106.14 ? 212 PRO C CD  1 
ATOM   7171  N  N   . ASN C 1 213 ? 323.564 228.367 278.538 1.00 107.70 ? 213 ASN C N   1 
ATOM   7172  C  CA  . ASN C 1 213 ? 322.184 228.375 279.010 1.00 107.41 ? 213 ASN C CA  1 
ATOM   7173  C  C   . ASN C 1 213 ? 321.334 229.434 278.321 1.00 99.95  ? 213 ASN C C   1 
ATOM   7174  O  O   . ASN C 1 213 ? 320.103 229.326 278.342 1.00 93.63  ? 213 ASN C O   1 
ATOM   7175  C  CB  . ASN C 1 213 ? 322.147 228.593 280.524 1.00 108.54 ? 213 ASN C CB  1 
ATOM   7176  C  CG  . ASN C 1 213 ? 323.266 227.869 281.245 1.00 113.09 ? 213 ASN C CG  1 
ATOM   7177  O  OD1 . ASN C 1 213 ? 324.422 228.290 281.202 1.00 114.41 ? 213 ASN C OD1 1 
ATOM   7178  N  ND2 . ASN C 1 213 ? 322.926 226.776 281.918 1.00 110.12 ? 213 ASN C ND2 1 
ATOM   7179  N  N   . ALA C 1 214 ? 321.952 230.447 277.719 1.00 100.59 ? 214 ALA C N   1 
ATOM   7180  C  CA  . ALA C 1 214 ? 321.192 231.541 277.129 1.00 91.58  ? 214 ALA C CA  1 
ATOM   7181  C  C   . ALA C 1 214 ? 320.203 231.015 276.098 1.00 85.22  ? 214 ALA C C   1 
ATOM   7182  O  O   . ALA C 1 214 ? 320.566 230.248 275.202 1.00 82.89  ? 214 ALA C O   1 
ATOM   7183  C  CB  . ALA C 1 214 ? 322.138 232.554 276.486 1.00 92.55  ? 214 ALA C CB  1 
ATOM   7184  N  N   . VAL C 1 215 ? 318.948 231.440 276.223 1.00 76.67  ? 215 VAL C N   1 
ATOM   7185  C  CA  . VAL C 1 215 ? 317.872 231.016 275.338 1.00 65.31  ? 215 VAL C CA  1 
ATOM   7186  C  C   . VAL C 1 215 ? 317.217 232.252 274.741 1.00 56.39  ? 215 VAL C C   1 
ATOM   7187  O  O   . VAL C 1 215 ? 317.029 233.261 275.429 1.00 56.98  ? 215 VAL C O   1 
ATOM   7188  C  CB  . VAL C 1 215 ? 316.830 230.151 276.076 1.00 65.59  ? 215 VAL C CB  1 
ATOM   7189  C  CG1 . VAL C 1 215 ? 317.522 229.148 276.981 1.00 70.42  ? 215 VAL C CG1 1 
ATOM   7190  C  CG2 . VAL C 1 215 ? 315.873 231.026 276.868 1.00 61.47  ? 215 VAL C CG2 1 
ATOM   7191  N  N   . VAL C 1 216 ? 316.878 232.172 273.458 1.00 52.03  ? 216 VAL C N   1 
ATOM   7192  C  CA  . VAL C 1 216 ? 316.187 233.240 272.749 1.00 44.38  ? 216 VAL C CA  1 
ATOM   7193  C  C   . VAL C 1 216 ? 314.743 232.813 272.539 1.00 41.22  ? 216 VAL C C   1 
ATOM   7194  O  O   . VAL C 1 216 ? 314.480 231.732 272.000 1.00 44.30  ? 216 VAL C O   1 
ATOM   7195  C  CB  . VAL C 1 216 ? 316.868 233.563 271.408 1.00 41.26  ? 216 VAL C CB  1 
ATOM   7196  C  CG1 . VAL C 1 216 ? 316.308 234.850 270.823 1.00 33.97  ? 216 VAL C CG1 1 
ATOM   7197  C  CG2 . VAL C 1 216 ? 318.369 233.666 271.594 1.00 37.10  ? 216 VAL C CG2 1 
ATOM   7198  N  N   . MET C 1 217 ? 313.811 233.659 272.962 1.00 39.24  ? 217 MET C N   1 
ATOM   7199  C  CA  . MET C 1 217 ? 312.391 233.386 272.804 1.00 34.46  ? 217 MET C CA  1 
ATOM   7200  C  C   . MET C 1 217 ? 311.897 234.037 271.520 1.00 35.15  ? 217 MET C C   1 
ATOM   7201  O  O   . MET C 1 217 ? 312.139 235.225 271.288 1.00 43.37  ? 217 MET C O   1 
ATOM   7202  C  CB  . MET C 1 217 ? 311.603 233.913 274.003 1.00 36.27  ? 217 MET C CB  1 
ATOM   7203  C  CG  . MET C 1 217 ? 311.891 233.198 275.315 1.00 38.30  ? 217 MET C CG  1 
ATOM   7204  S  SD  . MET C 1 217 ? 310.877 231.730 275.570 1.00 50.25  ? 217 MET C SD  1 
ATOM   7205  C  CE  . MET C 1 217 ? 311.940 230.463 274.893 1.00 42.76  ? 217 MET C CE  1 
ATOM   7206  N  N   . ILE C 1 218 ? 311.211 233.260 270.688 1.00 33.07  ? 218 ILE C N   1 
ATOM   7207  C  CA  . ILE C 1 218 ? 310.676 233.751 269.428 1.00 32.41  ? 218 ILE C CA  1 
ATOM   7208  C  C   . ILE C 1 218 ? 309.175 233.514 269.412 1.00 32.09  ? 218 ILE C C   1 
ATOM   7209  O  O   . ILE C 1 218 ? 308.667 232.554 270.003 1.00 34.15  ? 218 ILE C O   1 
ATOM   7210  C  CB  . ILE C 1 218 ? 311.344 233.077 268.209 1.00 31.40  ? 218 ILE C CB  1 
ATOM   7211  C  CG1 . ILE C 1 218 ? 311.259 231.554 268.325 1.00 33.46  ? 218 ILE C CG1 1 
ATOM   7212  C  CG2 . ILE C 1 218 ? 312.787 233.527 268.074 1.00 30.24  ? 218 ILE C CG2 1 
ATOM   7213  C  CD1 . ILE C 1 218 ? 310.045 230.958 267.644 1.00 33.87  ? 218 ILE C CD1 1 
ATOM   7214  N  N   . SER C 1 219 ? 308.470 234.399 268.713 1.00 34.83  ? 219 SER C N   1 
ATOM   7215  C  CA  . SER C 1 219 ? 307.028 234.325 268.544 1.00 32.31  ? 219 SER C CA  1 
ATOM   7216  C  C   . SER C 1 219 ? 306.701 234.125 267.073 1.00 31.33  ? 219 SER C C   1 
ATOM   7217  O  O   . SER C 1 219 ? 307.341 234.716 266.198 1.00 35.69  ? 219 SER C O   1 
ATOM   7218  C  CB  . SER C 1 219 ? 306.347 235.595 269.062 1.00 28.17  ? 219 SER C CB  1 
ATOM   7219  O  OG  . SER C 1 219 ? 306.309 235.613 270.476 1.00 33.41  ? 219 SER C OG  1 
ATOM   7220  N  N   . LYS C 1 220 ? 305.707 233.283 266.806 1.00 30.85  ? 220 LYS C N   1 
ATOM   7221  C  CA  . LYS C 1 220 ? 305.230 233.057 265.449 1.00 33.59  ? 220 LYS C CA  1 
ATOM   7222  C  C   . LYS C 1 220 ? 303.726 232.832 265.486 1.00 33.89  ? 220 LYS C C   1 
ATOM   7223  O  O   . LYS C 1 220 ? 303.134 232.639 266.546 1.00 37.77  ? 220 LYS C O   1 
ATOM   7224  C  CB  . LYS C 1 220 ? 305.936 231.871 264.783 1.00 31.40  ? 220 LYS C CB  1 
ATOM   7225  C  CG  . LYS C 1 220 ? 305.637 230.530 265.420 1.00 35.49  ? 220 LYS C CG  1 
ATOM   7226  C  CD  . LYS C 1 220 ? 306.247 229.406 264.611 1.00 34.59  ? 220 LYS C CD  1 
ATOM   7227  C  CE  . LYS C 1 220 ? 305.177 228.661 263.839 1.00 39.40  ? 220 LYS C CE  1 
ATOM   7228  N  NZ  . LYS C 1 220 ? 305.697 228.145 262.546 1.00 46.29  ? 220 LYS C NZ  1 
ATOM   7229  N  N   . ASP C 1 221 ? 303.103 232.873 264.314 1.00 33.11  ? 221 ASP C N   1 
ATOM   7230  C  CA  . ASP C 1 221 ? 301.669 232.667 264.183 1.00 27.92  ? 221 ASP C CA  1 
ATOM   7231  C  C   . ASP C 1 221 ? 301.398 231.342 263.486 1.00 31.66  ? 221 ASP C C   1 
ATOM   7232  O  O   . ASP C 1 221 ? 302.053 231.007 262.495 1.00 33.20  ? 221 ASP C O   1 
ATOM   7233  C  CB  . ASP C 1 221 ? 301.017 233.806 263.393 1.00 28.58  ? 221 ASP C CB  1 
ATOM   7234  C  CG  . ASP C 1 221 ? 301.074 235.130 264.123 1.00 36.28  ? 221 ASP C CG  1 
ATOM   7235  O  OD1 . ASP C 1 221 ? 300.570 235.207 265.262 1.00 42.85  ? 221 ASP C OD1 1 
ATOM   7236  O  OD2 . ASP C 1 221 ? 301.616 236.099 263.552 1.00 35.62  ? 221 ASP C OD2 1 
ATOM   7237  N  N   . THR C 1 222 ? 300.435 230.586 264.009 1.00 33.39  ? 222 THR C N   1 
ATOM   7238  C  CA  . THR C 1 222 ? 299.964 229.385 263.336 1.00 33.83  ? 222 THR C CA  1 
ATOM   7239  C  C   . THR C 1 222 ? 298.444 229.349 263.390 1.00 35.60  ? 222 THR C C   1 
ATOM   7240  O  O   . THR C 1 222 ? 297.812 230.028 264.203 1.00 39.74  ? 222 THR C O   1 
ATOM   7241  C  CB  . THR C 1 222 ? 300.548 228.095 263.939 1.00 41.09  ? 222 THR C CB  1 
ATOM   7242  O  OG1 . THR C 1 222 ? 300.109 226.968 263.164 1.00 49.87  ? 222 THR C OG1 1 
ATOM   7243  C  CG2 . THR C 1 222 ? 300.090 227.923 265.378 1.00 41.16  ? 222 THR C CG2 1 
ATOM   7244  N  N   . ALA C 1 223 ? 297.863 228.564 262.488 1.00 36.94  ? 223 ALA C N   1 
ATOM   7245  C  CA  . ALA C 1 223 ? 296.421 228.392 262.433 1.00 36.62  ? 223 ALA C CA  1 
ATOM   7246  C  C   . ALA C 1 223 ? 296.116 227.040 261.811 1.00 45.16  ? 223 ALA C C   1 
ATOM   7247  O  O   . ALA C 1 223 ? 296.890 226.524 261.001 1.00 48.85  ? 223 ALA C O   1 
ATOM   7248  C  CB  . ALA C 1 223 ? 295.746 229.512 261.633 1.00 32.44  ? 223 ALA C CB  1 
ATOM   7249  N  N   . PHE C 1 224 ? 294.981 226.468 262.199 1.00 49.91  ? 224 PHE C N   1 
ATOM   7250  C  CA  . PHE C 1 224 ? 294.581 225.180 261.649 1.00 50.52  ? 224 PHE C CA  1 
ATOM   7251  C  C   . PHE C 1 224 ? 293.070 225.023 261.744 1.00 53.30  ? 224 PHE C C   1 
ATOM   7252  O  O   . PHE C 1 224 ? 292.376 225.797 262.410 1.00 53.67  ? 224 PHE C O   1 
ATOM   7253  C  CB  . PHE C 1 224 ? 295.295 224.017 262.349 1.00 54.04  ? 224 PHE C CB  1 
ATOM   7254  C  CG  . PHE C 1 224 ? 295.350 224.140 263.843 1.00 55.27  ? 224 PHE C CG  1 
ATOM   7255  C  CD1 . PHE C 1 224 ? 294.340 223.615 264.631 1.00 57.82  ? 224 PHE C CD1 1 
ATOM   7256  C  CD2 . PHE C 1 224 ? 296.419 224.764 264.462 1.00 54.10  ? 224 PHE C CD2 1 
ATOM   7257  C  CE1 . PHE C 1 224 ? 294.389 223.720 266.006 1.00 54.11  ? 224 PHE C CE1 1 
ATOM   7258  C  CE2 . PHE C 1 224 ? 296.472 224.873 265.835 1.00 54.71  ? 224 PHE C CE2 1 
ATOM   7259  C  CZ  . PHE C 1 224 ? 295.456 224.350 266.609 1.00 54.38  ? 224 PHE C CZ  1 
ATOM   7260  N  N   . VAL C 1 225 ? 292.573 224.011 261.038 1.00 61.02  ? 225 VAL C N   1 
ATOM   7261  C  CA  . VAL C 1 225 ? 291.167 223.627 261.051 1.00 64.49  ? 225 VAL C CA  1 
ATOM   7262  C  C   . VAL C 1 225 ? 291.055 222.342 261.858 1.00 67.54  ? 225 VAL C C   1 
ATOM   7263  O  O   . VAL C 1 225 ? 291.612 221.309 261.468 1.00 68.53  ? 225 VAL C O   1 
ATOM   7264  C  CB  . VAL C 1 225 ? 290.620 223.425 259.630 1.00 61.87  ? 225 VAL C CB  1 
ATOM   7265  C  CG1 . VAL C 1 225 ? 290.321 224.758 258.975 1.00 56.43  ? 225 VAL C CG1 1 
ATOM   7266  C  CG2 . VAL C 1 225 ? 291.604 222.621 258.795 1.00 61.96  ? 225 VAL C CG2 1 
ATOM   7267  N  N   . ASP C 1 226 ? 290.339 222.400 262.976 1.00 71.75  ? 226 ASP C N   1 
ATOM   7268  C  CA  . ASP C 1 226 ? 290.157 221.218 263.802 1.00 79.23  ? 226 ASP C CA  1 
ATOM   7269  C  C   . ASP C 1 226 ? 289.083 220.316 263.197 1.00 84.44  ? 226 ASP C C   1 
ATOM   7270  O  O   . ASP C 1 226 ? 288.424 220.660 262.212 1.00 82.40  ? 226 ASP C O   1 
ATOM   7271  C  CB  . ASP C 1 226 ? 289.815 221.619 265.236 1.00 80.24  ? 226 ASP C CB  1 
ATOM   7272  C  CG  . ASP C 1 226 ? 288.557 222.461 265.326 1.00 79.33  ? 226 ASP C CG  1 
ATOM   7273  O  OD1 . ASP C 1 226 ? 287.781 222.488 264.349 1.00 78.78  ? 226 ASP C OD1 1 
ATOM   7274  O  OD2 . ASP C 1 226 ? 288.343 223.097 266.378 1.00 76.22  ? 226 ASP C OD2 1 
ATOM   7275  N  N   . GLU C 1 227 ? 288.903 219.137 263.797 1.00 86.91  ? 227 GLU C N   1 
ATOM   7276  C  CA  . GLU C 1 227 ? 287.900 218.203 263.296 1.00 90.87  ? 227 GLU C CA  1 
ATOM   7277  C  C   . GLU C 1 227 ? 286.505 218.814 263.311 1.00 88.46  ? 227 GLU C C   1 
ATOM   7278  O  O   . GLU C 1 227 ? 285.681 218.498 262.445 1.00 87.84  ? 227 GLU C O   1 
ATOM   7279  C  CB  . GLU C 1 227 ? 287.927 216.910 264.112 1.00 92.77  ? 227 GLU C CB  1 
ATOM   7280  C  CG  . GLU C 1 227 ? 287.293 217.021 265.490 1.00 96.87  ? 227 GLU C CG  1 
ATOM   7281  C  CD  . GLU C 1 227 ? 288.007 218.016 266.383 1.00 91.61  ? 227 GLU C CD  1 
ATOM   7282  O  OE1 . GLU C 1 227 ? 289.218 217.834 266.627 1.00 89.51  ? 227 GLU C OE1 1 
ATOM   7283  O  OE2 . GLU C 1 227 ? 287.359 218.981 266.839 1.00 87.97  ? 227 GLU C OE2 1 
ATOM   7284  N  N   . SER C 1 228 ? 286.218 219.684 264.280 1.00 86.14  ? 228 SER C N   1 
ATOM   7285  C  CA  . SER C 1 228 ? 284.926 220.358 264.325 1.00 82.53  ? 228 SER C CA  1 
ATOM   7286  C  C   . SER C 1 228 ? 284.770 221.412 263.237 1.00 83.16  ? 228 SER C C   1 
ATOM   7287  O  O   . SER C 1 228 ? 283.660 221.921 263.051 1.00 78.59  ? 228 SER C O   1 
ATOM   7288  C  CB  . SER C 1 228 ? 284.716 221.000 265.697 1.00 83.93  ? 228 SER C CB  1 
ATOM   7289  O  OG  . SER C 1 228 ? 285.005 220.086 266.740 1.00 89.66  ? 228 SER C OG  1 
ATOM   7290  N  N   . GLY C 1 229 ? 285.845 221.754 262.527 1.00 81.31  ? 229 GLY C N   1 
ATOM   7291  C  CA  . GLY C 1 229 ? 285.793 222.732 261.463 1.00 73.48  ? 229 GLY C CA  1 
ATOM   7292  C  C   . GLY C 1 229 ? 286.065 224.162 261.877 1.00 73.74  ? 229 GLY C C   1 
ATOM   7293  O  O   . GLY C 1 229 ? 286.146 225.035 261.004 1.00 74.72  ? 229 GLY C O   1 
ATOM   7294  N  N   . ASN C 1 230 ? 286.210 224.435 263.171 1.00 76.24  ? 230 ASN C N   1 
ATOM   7295  C  CA  . ASN C 1 230 ? 286.480 225.789 263.633 1.00 68.83  ? 230 ASN C CA  1 
ATOM   7296  C  C   . ASN C 1 230 ? 287.943 226.155 263.414 1.00 62.98  ? 230 ASN C C   1 
ATOM   7297  O  O   . ASN C 1 230 ? 288.840 225.313 263.512 1.00 61.09  ? 230 ASN C O   1 
ATOM   7298  C  CB  . ASN C 1 230 ? 286.127 225.935 265.114 1.00 69.91  ? 230 ASN C CB  1 
ATOM   7299  C  CG  . ASN C 1 230 ? 284.951 225.071 265.522 1.00 76.57  ? 230 ASN C CG  1 
ATOM   7300  O  OD1 . ASN C 1 230 ? 285.098 223.872 265.752 1.00 78.95  ? 230 ASN C OD1 1 
ATOM   7301  N  ND2 . ASN C 1 230 ? 283.775 225.680 265.616 1.00 71.67  ? 230 ASN C ND2 1 
ATOM   7302  N  N   . ILE C 1 231 ? 288.177 227.430 263.122 1.00 57.59  ? 231 ILE C N   1 
ATOM   7303  C  CA  . ILE C 1 231 ? 289.525 227.919 262.850 1.00 53.65  ? 231 ILE C CA  1 
ATOM   7304  C  C   . ILE C 1 231 ? 290.193 228.252 264.177 1.00 51.74  ? 231 ILE C C   1 
ATOM   7305  O  O   . ILE C 1 231 ? 289.693 229.084 264.942 1.00 55.06  ? 231 ILE C O   1 
ATOM   7306  C  CB  . ILE C 1 231 ? 289.494 229.147 261.929 1.00 50.74  ? 231 ILE C CB  1 
ATOM   7307  C  CG1 . ILE C 1 231 ? 288.973 228.769 260.544 1.00 51.20  ? 231 ILE C CG1 1 
ATOM   7308  C  CG2 . ILE C 1 231 ? 290.882 229.756 261.813 1.00 46.01  ? 231 ILE C CG2 1 
ATOM   7309  C  CD1 . ILE C 1 231 ? 289.253 227.347 260.162 1.00 52.21  ? 231 ILE C CD1 1 
ATOM   7310  N  N   . ILE C 1 232 ? 291.323 227.607 264.455 1.00 48.12  ? 232 ILE C N   1 
ATOM   7311  C  CA  . ILE C 1 232 ? 292.106 227.883 265.654 1.00 49.77  ? 232 ILE C CA  1 
ATOM   7312  C  C   . ILE C 1 232 ? 293.363 228.623 265.228 1.00 43.90  ? 232 ILE C C   1 
ATOM   7313  O  O   . ILE C 1 232 ? 294.195 228.076 264.493 1.00 46.79  ? 232 ILE C O   1 
ATOM   7314  C  CB  . ILE C 1 232 ? 292.451 226.597 266.421 1.00 54.42  ? 232 ILE C CB  1 
ATOM   7315  C  CG1 . ILE C 1 232 ? 291.210 225.717 266.577 1.00 51.99  ? 232 ILE C CG1 1 
ATOM   7316  C  CG2 . ILE C 1 232 ? 293.040 226.932 267.781 1.00 45.36  ? 232 ILE C CG2 1 
ATOM   7317  C  CD1 . ILE C 1 232 ? 290.046 226.419 267.238 1.00 49.17  ? 232 ILE C CD1 1 
ATOM   7318  N  N   . SER C 1 233 ? 293.493 229.868 265.677 1.00 41.66  ? 233 SER C N   1 
ATOM   7319  C  CA  . SER C 1 233 ? 294.666 230.693 265.428 1.00 40.00  ? 233 SER C CA  1 
ATOM   7320  C  C   . SER C 1 233 ? 295.371 230.971 266.747 1.00 39.50  ? 233 SER C C   1 
ATOM   7321  O  O   . SER C 1 233 ? 294.722 231.235 267.763 1.00 45.02  ? 233 SER C O   1 
ATOM   7322  C  CB  . SER C 1 233 ? 294.282 232.013 264.755 1.00 37.84  ? 233 SER C CB  1 
ATOM   7323  O  OG  . SER C 1 233 ? 293.935 231.815 263.396 1.00 48.24  ? 233 SER C OG  1 
ATOM   7324  N  N   . GLU C 1 234 ? 296.700 230.911 266.733 1.00 39.96  ? 234 GLU C N   1 
ATOM   7325  C  CA  . GLU C 1 234 ? 297.457 231.068 267.964 1.00 43.95  ? 234 GLU C CA  1 
ATOM   7326  C  C   . GLU C 1 234 ? 298.817 231.684 267.671 1.00 40.16  ? 234 GLU C C   1 
ATOM   7327  O  O   . GLU C 1 234 ? 299.348 231.572 266.560 1.00 39.26  ? 234 GLU C O   1 
ATOM   7328  C  CB  . GLU C 1 234 ? 297.626 229.723 268.680 1.00 43.26  ? 234 GLU C CB  1 
ATOM   7329  C  CG  . GLU C 1 234 ? 298.520 229.774 269.902 1.00 44.82  ? 234 GLU C CG  1 
ATOM   7330  C  CD  . GLU C 1 234 ? 299.107 228.423 270.245 1.00 56.62  ? 234 GLU C CD  1 
ATOM   7331  O  OE1 . GLU C 1 234 ? 298.930 227.479 269.447 1.00 58.24  ? 234 GLU C OE1 1 
ATOM   7332  O  OE2 . GLU C 1 234 ? 299.750 228.305 271.310 1.00 58.79  ? 234 GLU C OE2 1 
ATOM   7333  N  N   . THR C 1 235 ? 299.362 232.355 268.681 1.00 37.80  ? 235 THR C N   1 
ATOM   7334  C  CA  . THR C 1 235 ? 300.731 232.853 268.667 1.00 35.82  ? 235 THR C CA  1 
ATOM   7335  C  C   . THR C 1 235 ? 301.567 231.964 269.578 1.00 36.56  ? 235 THR C C   1 
ATOM   7336  O  O   . THR C 1 235 ? 301.308 231.883 270.783 1.00 41.10  ? 235 THR C O   1 
ATOM   7337  C  CB  . THR C 1 235 ? 300.801 234.310 269.123 1.00 36.01  ? 235 THR C CB  1 
ATOM   7338  O  OG1 . THR C 1 235 ? 299.720 235.049 268.542 1.00 37.97  ? 235 THR C OG1 1 
ATOM   7339  C  CG2 . THR C 1 235 ? 302.119 234.937 268.699 1.00 29.19  ? 235 THR C CG2 1 
ATOM   7340  N  N   . ILE C 1 236 ? 302.566 231.308 269.001 1.00 36.37  ? 236 ILE C N   1 
ATOM   7341  C  CA  . ILE C 1 236 ? 303.430 230.380 269.717 1.00 39.43  ? 236 ILE C CA  1 
ATOM   7342  C  C   . ILE C 1 236 ? 304.719 231.096 270.086 1.00 38.64  ? 236 ILE C C   1 
ATOM   7343  O  O   . ILE C 1 236 ? 305.389 231.671 269.219 1.00 40.22  ? 236 ILE C O   1 
ATOM   7344  C  CB  . ILE C 1 236 ? 303.726 229.130 268.871 1.00 42.69  ? 236 ILE C CB  1 
ATOM   7345  C  CG1 . ILE C 1 236 ? 302.460 228.294 268.689 1.00 39.77  ? 236 ILE C CG1 1 
ATOM   7346  C  CG2 . ILE C 1 236 ? 304.830 228.309 269.510 1.00 40.20  ? 236 ILE C CG2 1 
ATOM   7347  C  CD1 . ILE C 1 236 ? 302.617 227.175 267.693 1.00 44.44  ? 236 ILE C CD1 1 
ATOM   7348  N  N   . THR C 1 237 ? 305.062 231.062 271.370 1.00 40.59  ? 237 THR C N   1 
ATOM   7349  C  CA  . THR C 1 237 ? 306.329 231.573 271.877 1.00 41.58  ? 237 THR C CA  1 
ATOM   7350  C  C   . THR C 1 237 ? 307.157 230.388 272.354 1.00 40.22  ? 237 THR C C   1 
ATOM   7351  O  O   . THR C 1 237 ? 306.707 229.617 273.208 1.00 45.29  ? 237 THR C O   1 
ATOM   7352  C  CB  . THR C 1 237 ? 306.108 232.570 273.015 1.00 38.07  ? 237 THR C CB  1 
ATOM   7353  O  OG1 . THR C 1 237 ? 305.354 233.688 272.531 1.00 34.86  ? 237 THR C OG1 1 
ATOM   7354  C  CG2 . THR C 1 237 ? 307.441 233.062 273.564 1.00 31.81  ? 237 THR C CG2 1 
ATOM   7355  N  N   . ARG C 1 238 ? 308.358 230.242 271.805 1.00 37.91  ? 238 ARG C N   1 
ATOM   7356  C  CA  . ARG C 1 238 ? 309.184 229.084 272.117 1.00 35.91  ? 238 ARG C CA  1 
ATOM   7357  C  C   . ARG C 1 238 ? 310.642 229.448 271.893 1.00 38.49  ? 238 ARG C C   1 
ATOM   7358  O  O   . ARG C 1 238 ? 310.942 230.444 271.227 1.00 37.78  ? 238 ARG C O   1 
ATOM   7359  C  CB  . ARG C 1 238 ? 308.798 227.872 271.257 1.00 35.45  ? 238 ARG C CB  1 
ATOM   7360  C  CG  . ARG C 1 238 ? 308.953 228.101 269.770 1.00 37.11  ? 238 ARG C CG  1 
ATOM   7361  C  CD  . ARG C 1 238 ? 308.342 226.968 268.979 1.00 37.08  ? 238 ARG C CD  1 
ATOM   7362  N  NE  . ARG C 1 238 ? 308.798 226.962 267.595 1.00 40.12  ? 238 ARG C NE  1 
ATOM   7363  C  CZ  . ARG C 1 238 ? 308.132 226.407 266.594 1.00 42.78  ? 238 ARG C CZ  1 
ATOM   7364  N  NH1 . ARG C 1 238 ? 306.974 225.798 266.788 1.00 46.98  ? 238 ARG C NH1 1 
ATOM   7365  N  NH2 . ARG C 1 238 ? 308.640 226.462 265.367 1.00 43.64  ? 238 ARG C NH2 1 
ATOM   7366  N  N   . PRO C 1 239 ? 311.569 228.668 272.444 1.00 42.59  ? 239 PRO C N   1 
ATOM   7367  C  CA  . PRO C 1 239 ? 312.991 228.925 272.191 1.00 38.98  ? 239 PRO C CA  1 
ATOM   7368  C  C   . PRO C 1 239 ? 313.319 228.800 270.712 1.00 38.38  ? 239 PRO C C   1 
ATOM   7369  O  O   . PRO C 1 239 ? 312.768 227.959 270.000 1.00 37.61  ? 239 PRO C O   1 
ATOM   7370  C  CB  . PRO C 1 239 ? 313.700 227.846 273.018 1.00 37.89  ? 239 PRO C CB  1 
ATOM   7371  C  CG  . PRO C 1 239 ? 312.695 227.420 274.036 1.00 36.84  ? 239 PRO C CG  1 
ATOM   7372  C  CD  . PRO C 1 239 ? 311.364 227.544 273.370 1.00 37.42  ? 239 PRO C CD  1 
ATOM   7373  N  N   . LEU C 1 240 ? 314.232 229.651 270.254 1.00 38.84  ? 240 LEU C N   1 
ATOM   7374  C  CA  . LEU C 1 240 ? 314.659 229.635 268.862 1.00 35.76  ? 240 LEU C CA  1 
ATOM   7375  C  C   . LEU C 1 240 ? 315.491 228.388 268.591 1.00 38.27  ? 240 LEU C C   1 
ATOM   7376  O  O   . LEU C 1 240 ? 316.563 228.211 269.178 1.00 43.95  ? 240 LEU C O   1 
ATOM   7377  C  CB  . LEU C 1 240 ? 315.458 230.897 268.551 1.00 36.01  ? 240 LEU C CB  1 
ATOM   7378  C  CG  . LEU C 1 240 ? 316.530 230.795 267.467 1.00 39.58  ? 240 LEU C CG  1 
ATOM   7379  C  CD1 . LEU C 1 240 ? 315.889 230.647 266.099 1.00 37.84  ? 240 LEU C CD1 1 
ATOM   7380  C  CD2 . LEU C 1 240 ? 317.448 232.003 267.508 1.00 33.61  ? 240 LEU C CD2 1 
ATOM   7381  N  N   . SER C 1 241 ? 315.001 227.519 267.706 1.00 39.00  ? 241 SER C N   1 
ATOM   7382  C  CA  . SER C 1 241 ? 315.688 226.267 267.414 1.00 38.80  ? 241 SER C CA  1 
ATOM   7383  C  C   . SER C 1 241 ? 315.818 225.930 265.936 1.00 40.78  ? 241 SER C C   1 
ATOM   7384  O  O   . SER C 1 241 ? 316.726 225.167 265.586 1.00 46.79  ? 241 SER C O   1 
ATOM   7385  C  CB  . SER C 1 241 ? 314.987 225.095 268.118 1.00 42.25  ? 241 SER C CB  1 
ATOM   7386  O  OG  . SER C 1 241 ? 313.585 225.141 267.921 1.00 47.33  ? 241 SER C OG  1 
ATOM   7387  N  N   . SER C 1 242 ? 314.967 226.460 265.059 1.00 41.82  ? 242 SER C N   1 
ATOM   7388  C  CA  . SER C 1 242 ? 314.971 226.042 263.663 1.00 42.56  ? 242 SER C CA  1 
ATOM   7389  C  C   . SER C 1 242 ? 314.394 227.152 262.793 1.00 39.96  ? 242 SER C C   1 
ATOM   7390  O  O   . SER C 1 242 ? 313.959 228.197 263.283 1.00 42.35  ? 242 SER C O   1 
ATOM   7391  C  CB  . SER C 1 242 ? 314.191 224.737 263.481 1.00 42.91  ? 242 SER C CB  1 
ATOM   7392  O  OG  . SER C 1 242 ? 312.901 224.827 264.061 1.00 42.44  ? 242 SER C OG  1 
ATOM   7393  N  N   . GLU C 1 243 ? 314.393 226.907 261.479 1.00 38.07  ? 243 GLU C N   1 
ATOM   7394  C  CA  . GLU C 1 243 ? 313.854 227.879 260.534 1.00 39.29  ? 243 GLU C CA  1 
ATOM   7395  C  C   . GLU C 1 243 ? 312.338 227.985 260.636 1.00 39.76  ? 243 GLU C C   1 
ATOM   7396  O  O   . GLU C 1 243 ? 311.771 229.042 260.337 1.00 37.63  ? 243 GLU C O   1 
ATOM   7397  C  CB  . GLU C 1 243 ? 314.260 227.508 259.107 1.00 33.49  ? 243 GLU C CB  1 
ATOM   7398  C  CG  . GLU C 1 243 ? 315.748 227.634 258.828 1.00 40.31  ? 243 GLU C CG  1 
ATOM   7399  C  CD  . GLU C 1 243 ? 316.486 226.320 258.994 1.00 53.46  ? 243 GLU C CD  1 
ATOM   7400  O  OE1 . GLU C 1 243 ? 316.051 225.494 259.823 1.00 53.79  ? 243 GLU C OE1 1 
ATOM   7401  O  OE2 . GLU C 1 243 ? 317.499 226.112 258.296 1.00 54.54  ? 243 GLU C OE2 1 
ATOM   7402  N  N   . TYR C 1 244 ? 311.668 226.915 261.069 1.00 39.77  ? 244 TYR C N   1 
ATOM   7403  C  CA  . TYR C 1 244 ? 310.218 226.959 261.201 1.00 38.23  ? 244 TYR C CA  1 
ATOM   7404  C  C   . TYR C 1 244 ? 309.775 227.993 262.223 1.00 39.35  ? 244 TYR C C   1 
ATOM   7405  O  O   . TYR C 1 244 ? 308.596 228.361 262.248 1.00 45.52  ? 244 TYR C O   1 
ATOM   7406  C  CB  . TYR C 1 244 ? 309.678 225.581 261.584 1.00 45.06  ? 244 TYR C CB  1 
ATOM   7407  C  CG  . TYR C 1 244 ? 309.699 224.576 260.457 1.00 53.25  ? 244 TYR C CG  1 
ATOM   7408  C  CD1 . TYR C 1 244 ? 308.801 224.667 259.404 1.00 54.06  ? 244 TYR C CD1 1 
ATOM   7409  C  CD2 . TYR C 1 244 ? 310.613 223.532 260.449 1.00 54.86  ? 244 TYR C CD2 1 
ATOM   7410  C  CE1 . TYR C 1 244 ? 308.815 223.751 258.373 1.00 55.19  ? 244 TYR C CE1 1 
ATOM   7411  C  CE2 . TYR C 1 244 ? 310.634 222.610 259.423 1.00 60.40  ? 244 TYR C CE2 1 
ATOM   7412  C  CZ  . TYR C 1 244 ? 309.734 222.724 258.387 1.00 61.05  ? 244 TYR C CZ  1 
ATOM   7413  O  OH  . TYR C 1 244 ? 309.753 221.806 257.362 1.00 67.56  ? 244 TYR C OH  1 
ATOM   7414  N  N   . ASP C 1 245 ? 310.691 228.467 263.066 1.00 36.72  ? 245 ASP C N   1 
ATOM   7415  C  CA  . ASP C 1 245 ? 310.380 229.534 264.005 1.00 36.15  ? 245 ASP C CA  1 
ATOM   7416  C  C   . ASP C 1 245 ? 310.076 230.854 263.311 1.00 33.41  ? 245 ASP C C   1 
ATOM   7417  O  O   . ASP C 1 245 ? 309.562 231.769 263.961 1.00 39.46  ? 245 ASP C O   1 
ATOM   7418  C  CB  . ASP C 1 245 ? 311.541 229.724 264.983 1.00 38.01  ? 245 ASP C CB  1 
ATOM   7419  C  CG  . ASP C 1 245 ? 311.749 228.523 265.887 1.00 43.78  ? 245 ASP C CG  1 
ATOM   7420  O  OD1 . ASP C 1 245 ? 311.457 227.388 265.459 1.00 46.43  ? 245 ASP C OD1 1 
ATOM   7421  O  OD2 . ASP C 1 245 ? 312.212 228.716 267.028 1.00 45.99  ? 245 ASP C OD2 1 
ATOM   7422  N  N   . PHE C 1 246 ? 310.380 230.977 262.018 1.00 32.68  ? 246 PHE C N   1 
ATOM   7423  C  CA  . PHE C 1 246 ? 310.193 232.221 261.284 1.00 31.31  ? 246 PHE C CA  1 
ATOM   7424  C  C   . PHE C 1 246 ? 309.076 232.127 260.249 1.00 32.43  ? 246 PHE C C   1 
ATOM   7425  O  O   . PHE C 1 246 ? 308.971 232.991 259.374 1.00 32.03  ? 246 PHE C O   1 
ATOM   7426  C  CB  . PHE C 1 246 ? 311.504 232.640 260.616 1.00 28.16  ? 246 PHE C CB  1 
ATOM   7427  C  CG  . PHE C 1 246 ? 312.665 232.717 261.564 1.00 31.64  ? 246 PHE C CG  1 
ATOM   7428  C  CD1 . PHE C 1 246 ? 312.691 233.668 262.567 1.00 25.84  ? 246 PHE C CD1 1 
ATOM   7429  C  CD2 . PHE C 1 246 ? 313.729 231.839 261.454 1.00 31.82  ? 246 PHE C CD2 1 
ATOM   7430  C  CE1 . PHE C 1 246 ? 313.751 233.742 263.442 1.00 25.52  ? 246 PHE C CE1 1 
ATOM   7431  C  CE2 . PHE C 1 246 ? 314.794 231.911 262.326 1.00 32.00  ? 246 PHE C CE2 1 
ATOM   7432  C  CZ  . PHE C 1 246 ? 314.804 232.864 263.321 1.00 32.77  ? 246 PHE C CZ  1 
ATOM   7433  N  N   . LEU C 1 247 ? 308.240 231.098 260.332 1.00 32.76  ? 247 LEU C N   1 
ATOM   7434  C  CA  . LEU C 1 247 ? 307.121 230.910 259.420 1.00 31.90  ? 247 LEU C CA  1 
ATOM   7435  C  C   . LEU C 1 247 ? 305.822 231.242 260.141 1.00 29.65  ? 247 LEU C C   1 
ATOM   7436  O  O   . LEU C 1 247 ? 305.564 230.724 261.231 1.00 33.54  ? 247 LEU C O   1 
ATOM   7437  C  CB  . LEU C 1 247 ? 307.086 229.475 258.892 1.00 34.06  ? 247 LEU C CB  1 
ATOM   7438  C  CG  . LEU C 1 247 ? 305.933 229.090 257.966 1.00 33.12  ? 247 LEU C CG  1 
ATOM   7439  C  CD1 . LEU C 1 247 ? 306.191 229.580 256.552 1.00 28.14  ? 247 LEU C CD1 1 
ATOM   7440  C  CD2 . LEU C 1 247 ? 305.729 227.588 257.983 1.00 38.42  ? 247 LEU C CD2 1 
ATOM   7441  N  N   . ASN C 1 248 ? 305.009 232.103 259.535 1.00 28.56  ? 248 ASN C N   1 
ATOM   7442  C  CA  . ASN C 1 248 ? 303.727 232.508 260.092 1.00 25.90  ? 248 ASN C CA  1 
ATOM   7443  C  C   . ASN C 1 248 ? 302.609 231.988 259.200 1.00 26.41  ? 248 ASN C C   1 
ATOM   7444  O  O   . ASN C 1 248 ? 302.636 232.193 257.985 1.00 29.58  ? 248 ASN C O   1 
ATOM   7445  C  CB  . ASN C 1 248 ? 303.643 234.030 260.219 1.00 26.03  ? 248 ASN C CB  1 
ATOM   7446  C  CG  . ASN C 1 248 ? 304.692 234.596 261.152 1.00 29.71  ? 248 ASN C CG  1 
ATOM   7447  O  OD1 . ASN C 1 248 ? 304.645 234.379 262.361 1.00 32.53  ? 248 ASN C OD1 1 
ATOM   7448  N  ND2 . ASN C 1 248 ? 305.648 235.328 260.594 1.00 33.00  ? 248 ASN C ND2 1 
ATOM   7449  N  N   . THR C 1 249 ? 301.630 231.323 259.804 1.00 26.15  ? 249 THR C N   1 
ATOM   7450  C  CA  . THR C 1 249 ? 300.520 230.714 259.082 1.00 26.28  ? 249 THR C CA  1 
ATOM   7451  C  C   . THR C 1 249 ? 299.225 231.414 259.466 1.00 22.12  ? 249 THR C C   1 
ATOM   7452  O  O   . THR C 1 249 ? 298.964 231.634 260.652 1.00 23.10  ? 249 THR C O   1 
ATOM   7453  C  CB  . THR C 1 249 ? 300.421 229.217 259.387 1.00 32.59  ? 249 THR C CB  1 
ATOM   7454  O  OG1 . THR C 1 249 ? 301.727 228.630 259.329 1.00 41.10  ? 249 THR C OG1 1 
ATOM   7455  C  CG2 . THR C 1 249 ? 299.514 228.524 258.384 1.00 27.33  ? 249 THR C CG2 1 
ATOM   7456  N  N   . TYR C 1 250 ? 298.419 231.766 258.466 1.00 24.82  ? 250 TYR C N   1 
ATOM   7457  C  CA  . TYR C 1 250 ? 297.157 232.452 258.691 1.00 22.70  ? 250 TYR C CA  1 
ATOM   7458  C  C   . TYR C 1 250 ? 296.046 231.772 257.909 1.00 22.87  ? 250 TYR C C   1 
ATOM   7459  O  O   . TYR C 1 250 ? 296.232 231.389 256.749 1.00 25.57  ? 250 TYR C O   1 
ATOM   7460  C  CB  . TYR C 1 250 ? 297.232 233.929 258.279 1.00 20.17  ? 250 TYR C CB  1 
ATOM   7461  C  CG  . TYR C 1 250 ? 298.401 234.685 258.858 1.00 22.68  ? 250 TYR C CG  1 
ATOM   7462  C  CD1 . TYR C 1 250 ? 299.627 234.709 258.211 1.00 21.03  ? 250 TYR C CD1 1 
ATOM   7463  C  CD2 . TYR C 1 250 ? 298.277 235.382 260.051 1.00 23.91  ? 250 TYR C CD2 1 
ATOM   7464  C  CE1 . TYR C 1 250 ? 300.696 235.400 258.736 1.00 21.80  ? 250 TYR C CE1 1 
ATOM   7465  C  CE2 . TYR C 1 250 ? 299.341 236.076 260.584 1.00 25.84  ? 250 TYR C CE2 1 
ATOM   7466  C  CZ  . TYR C 1 250 ? 300.548 236.082 259.923 1.00 25.73  ? 250 TYR C CZ  1 
ATOM   7467  O  OH  . TYR C 1 250 ? 301.611 236.774 260.451 1.00 25.19  ? 250 TYR C OH  1 
ATOM   7468  N  N   . ILE C 1 251 ? 294.893 231.626 258.553 1.00 27.52  ? 251 ILE C N   1 
ATOM   7469  C  CA  . ILE C 1 251 ? 293.644 231.270 257.891 1.00 25.57  ? 251 ILE C CA  1 
ATOM   7470  C  C   . ILE C 1 251 ? 292.675 232.409 258.170 1.00 24.81  ? 251 ILE C C   1 
ATOM   7471  O  O   . ILE C 1 251 ? 292.249 232.606 259.315 1.00 29.17  ? 251 ILE C O   1 
ATOM   7472  C  CB  . ILE C 1 251 ? 293.085 229.928 258.378 1.00 30.20  ? 251 ILE C CB  1 
ATOM   7473  C  CG1 . ILE C 1 251 ? 294.184 228.864 258.386 1.00 28.76  ? 251 ILE C CG1 1 
ATOM   7474  C  CG2 . ILE C 1 251 ? 291.926 229.489 257.499 1.00 31.73  ? 251 ILE C CG2 1 
ATOM   7475  C  CD1 . ILE C 1 251 ? 293.694 227.488 258.766 1.00 29.92  ? 251 ILE C CD1 1 
ATOM   7476  N  N   . VAL C 1 252 ? 292.326 233.158 257.130 1.00 21.04  ? 252 VAL C N   1 
ATOM   7477  C  CA  . VAL C 1 252 ? 291.611 234.420 257.261 1.00 22.18  ? 252 VAL C CA  1 
ATOM   7478  C  C   . VAL C 1 252 ? 290.304 234.315 256.488 1.00 23.11  ? 252 VAL C C   1 
ATOM   7479  O  O   . VAL C 1 252 ? 290.321 233.926 255.319 1.00 26.43  ? 252 VAL C O   1 
ATOM   7480  C  CB  . VAL C 1 252 ? 292.433 235.616 256.748 1.00 20.71  ? 252 VAL C CB  1 
ATOM   7481  C  CG1 . VAL C 1 252 ? 291.797 236.925 257.185 1.00 17.09  ? 252 VAL C CG1 1 
ATOM   7482  C  CG2 . VAL C 1 252 ? 293.868 235.523 257.238 1.00 19.57  ? 252 VAL C CG2 1 
ATOM   7483  N  N   . PRO C 1 253 ? 289.160 234.635 257.091 1.00 22.77  ? 253 PRO C N   1 
ATOM   7484  C  CA  . PRO C 1 253 ? 287.928 234.802 256.304 1.00 21.37  ? 253 PRO C CA  1 
ATOM   7485  C  C   . PRO C 1 253 ? 288.031 236.068 255.466 1.00 21.76  ? 253 PRO C C   1 
ATOM   7486  O  O   . PRO C 1 253 ? 288.225 237.162 255.999 1.00 22.86  ? 253 PRO C O   1 
ATOM   7487  C  CB  . PRO C 1 253 ? 286.830 234.908 257.369 1.00 20.86  ? 253 PRO C CB  1 
ATOM   7488  C  CG  . PRO C 1 253 ? 287.456 234.455 258.647 1.00 18.15  ? 253 PRO C CG  1 
ATOM   7489  C  CD  . PRO C 1 253 ? 288.917 234.727 258.538 1.00 20.82  ? 253 PRO C CD  1 
ATOM   7490  N  N   . ILE C 1 254 ? 287.899 235.918 254.150 1.00 22.54  ? 254 ILE C N   1 
ATOM   7491  C  CA  . ILE C 1 254 ? 288.258 236.977 253.214 1.00 20.00  ? 254 ILE C CA  1 
ATOM   7492  C  C   . ILE C 1 254 ? 287.058 237.596 252.521 1.00 21.70  ? 254 ILE C C   1 
ATOM   7493  O  O   . ILE C 1 254 ? 287.240 238.501 251.696 1.00 25.01  ? 254 ILE C O   1 
ATOM   7494  C  CB  . ILE C 1 254 ? 289.273 236.474 252.171 1.00 15.90  ? 254 ILE C CB  1 
ATOM   7495  C  CG1 . ILE C 1 254 ? 288.785 235.171 251.535 1.00 18.91  ? 254 ILE C CG1 1 
ATOM   7496  C  CG2 . ILE C 1 254 ? 290.639 236.287 252.811 1.00 20.17  ? 254 ILE C CG2 1 
ATOM   7497  C  CD1 . ILE C 1 254 ? 288.219 235.345 250.145 1.00 21.06  ? 254 ILE C CD1 1 
ATOM   7498  N  N   . TYR C 1 255 ? 285.843 237.153 252.820 1.00 22.65  ? 255 TYR C N   1 
ATOM   7499  C  CA  . TYR C 1 255 ? 284.687 237.759 252.177 1.00 21.41  ? 255 TYR C CA  1 
ATOM   7500  C  C   . TYR C 1 255 ? 284.474 239.176 252.705 1.00 23.25  ? 255 TYR C C   1 
ATOM   7501  O  O   . TYR C 1 255 ? 284.551 239.408 253.915 1.00 27.07  ? 255 TYR C O   1 
ATOM   7502  C  CB  . TYR C 1 255 ? 283.432 236.921 252.399 1.00 25.45  ? 255 TYR C CB  1 
ATOM   7503  C  CG  . TYR C 1 255 ? 282.384 237.151 251.336 1.00 27.90  ? 255 TYR C CG  1 
ATOM   7504  C  CD1 . TYR C 1 255 ? 282.459 236.506 250.111 1.00 27.82  ? 255 TYR C CD1 1 
ATOM   7505  C  CD2 . TYR C 1 255 ? 281.328 238.023 251.552 1.00 26.74  ? 255 TYR C CD2 1 
ATOM   7506  C  CE1 . TYR C 1 255 ? 281.510 236.718 249.134 1.00 24.93  ? 255 TYR C CE1 1 
ATOM   7507  C  CE2 . TYR C 1 255 ? 280.374 238.240 250.582 1.00 26.51  ? 255 TYR C CE2 1 
ATOM   7508  C  CZ  . TYR C 1 255 ? 280.469 237.585 249.375 1.00 28.96  ? 255 TYR C CZ  1 
ATOM   7509  O  OH  . TYR C 1 255 ? 279.520 237.797 248.403 1.00 33.74  ? 255 TYR C OH  1 
ATOM   7510  N  N   . PRO C 1 256 ? 284.210 240.143 251.826 1.00 23.34  ? 256 PRO C N   1 
ATOM   7511  C  CA  . PRO C 1 256 ? 284.082 241.532 252.277 1.00 22.12  ? 256 PRO C CA  1 
ATOM   7512  C  C   . PRO C 1 256 ? 282.958 241.696 253.288 1.00 23.62  ? 256 PRO C C   1 
ATOM   7513  O  O   . PRO C 1 256 ? 281.928 241.022 253.225 1.00 30.92  ? 256 PRO C O   1 
ATOM   7514  C  CB  . PRO C 1 256 ? 283.783 242.302 250.985 1.00 20.89  ? 256 PRO C CB  1 
ATOM   7515  C  CG  . PRO C 1 256 ? 284.269 241.428 249.889 1.00 19.30  ? 256 PRO C CG  1 
ATOM   7516  C  CD  . PRO C 1 256 ? 284.107 240.017 250.363 1.00 20.31  ? 256 PRO C CD  1 
ATOM   7517  N  N   . ASP C 1 257 ? 283.173 242.606 254.234 1.00 24.49  ? 257 ASP C N   1 
ATOM   7518  C  CA  . ASP C 1 257 ? 282.159 242.950 255.227 1.00 26.09  ? 257 ASP C CA  1 
ATOM   7519  C  C   . ASP C 1 257 ? 281.231 243.989 254.611 1.00 26.08  ? 257 ASP C C   1 
ATOM   7520  O  O   . ASP C 1 257 ? 281.521 245.186 254.627 1.00 32.10  ? 257 ASP C O   1 
ATOM   7521  C  CB  . ASP C 1 257 ? 282.811 243.473 256.501 1.00 26.12  ? 257 ASP C CB  1 
ATOM   7522  C  CG  . ASP C 1 257 ? 281.799 243.972 257.511 1.00 36.33  ? 257 ASP C CG  1 
ATOM   7523  O  OD1 . ASP C 1 257 ? 280.700 243.386 257.590 1.00 35.41  ? 257 ASP C OD1 1 
ATOM   7524  O  OD2 . ASP C 1 257 ? 282.098 244.955 258.220 1.00 38.06  ? 257 ASP C OD2 1 
ATOM   7525  N  N   . GLU C 1 258 ? 280.109 243.531 254.057 1.00 26.27  ? 258 GLU C N   1 
ATOM   7526  C  CA  . GLU C 1 258 ? 279.185 244.435 253.386 1.00 23.03  ? 258 GLU C CA  1 
ATOM   7527  C  C   . GLU C 1 258 ? 278.318 245.225 254.356 1.00 23.15  ? 258 GLU C C   1 
ATOM   7528  O  O   . GLU C 1 258 ? 277.751 246.249 253.963 1.00 25.35  ? 258 GLU C O   1 
ATOM   7529  C  CB  . GLU C 1 258 ? 278.294 243.654 252.422 1.00 24.37  ? 258 GLU C CB  1 
ATOM   7530  C  CG  . GLU C 1 258 ? 279.057 242.927 251.335 1.00 29.08  ? 258 GLU C CG  1 
ATOM   7531  C  CD  . GLU C 1 258 ? 278.252 241.811 250.709 1.00 38.79  ? 258 GLU C CD  1 
ATOM   7532  O  OE1 . GLU C 1 258 ? 277.921 240.842 251.423 1.00 37.13  ? 258 GLU C OE1 1 
ATOM   7533  O  OE2 . GLU C 1 258 ? 277.948 241.904 249.503 1.00 44.60  ? 258 GLU C OE2 1 
ATOM   7534  N  N   . THR C 1 259 ? 278.208 244.781 255.607 1.00 27.07  ? 259 THR C N   1 
ATOM   7535  C  CA  . THR C 1 259 ? 277.387 245.484 256.583 1.00 25.10  ? 259 THR C CA  1 
ATOM   7536  C  C   . THR C 1 259 ? 277.989 246.813 257.017 1.00 26.00  ? 259 THR C C   1 
ATOM   7537  O  O   . THR C 1 259 ? 277.300 247.595 257.681 1.00 29.80  ? 259 THR C O   1 
ATOM   7538  C  CB  . THR C 1 259 ? 277.157 244.595 257.804 1.00 26.45  ? 259 THR C CB  1 
ATOM   7539  O  OG1 . THR C 1 259 ? 278.384 244.451 258.529 1.00 34.99  ? 259 THR C OG1 1 
ATOM   7540  C  CG2 . THR C 1 259 ? 276.673 243.223 257.372 1.00 21.76  ? 259 THR C CG2 1 
ATOM   7541  N  N   . CYS C 1 260 ? 279.242 247.091 256.647 1.00 28.09  ? 260 CYS C N   1 
ATOM   7542  C  CA  . CYS C 1 260 ? 279.879 248.342 257.048 1.00 23.10  ? 260 CYS C CA  1 
ATOM   7543  C  C   . CYS C 1 260 ? 279.015 249.544 256.695 1.00 25.21  ? 260 CYS C C   1 
ATOM   7544  O  O   . CYS C 1 260 ? 278.863 250.468 257.502 1.00 28.08  ? 260 CYS C O   1 
ATOM   7545  C  CB  . CYS C 1 260 ? 281.256 248.461 256.392 1.00 23.79  ? 260 CYS C CB  1 
ATOM   7546  S  SG  . CYS C 1 260 ? 281.266 248.224 254.600 1.00 31.13  ? 260 CYS C SG  1 
ATOM   7547  N  N   . TRP C 1 261 ? 278.425 249.541 255.497 1.00 25.17  ? 261 TRP C N   1 
ATOM   7548  C  CA  . TRP C 1 261 ? 277.583 250.654 255.073 1.00 23.20  ? 261 TRP C CA  1 
ATOM   7549  C  C   . TRP C 1 261 ? 276.521 250.976 256.115 1.00 26.36  ? 261 TRP C C   1 
ATOM   7550  O  O   . TRP C 1 261 ? 276.257 252.148 256.405 1.00 30.91  ? 261 TRP C O   1 
ATOM   7551  C  CB  . TRP C 1 261 ? 276.918 250.328 253.738 1.00 21.09  ? 261 TRP C CB  1 
ATOM   7552  C  CG  . TRP C 1 261 ? 277.870 250.169 252.604 1.00 21.32  ? 261 TRP C CG  1 
ATOM   7553  C  CD1 . TRP C 1 261 ? 278.325 248.999 252.083 1.00 20.70  ? 261 TRP C CD1 1 
ATOM   7554  C  CD2 . TRP C 1 261 ? 278.469 251.214 251.830 1.00 19.28  ? 261 TRP C CD2 1 
ATOM   7555  N  NE1 . TRP C 1 261 ? 279.178 249.245 251.039 1.00 18.30  ? 261 TRP C NE1 1 
ATOM   7556  C  CE2 . TRP C 1 261 ? 279.284 250.599 250.863 1.00 17.91  ? 261 TRP C CE2 1 
ATOM   7557  C  CE3 . TRP C 1 261 ? 278.399 252.609 251.865 1.00 20.54  ? 261 TRP C CE3 1 
ATOM   7558  C  CZ2 . TRP C 1 261 ? 280.023 251.329 249.939 1.00 21.98  ? 261 TRP C CZ2 1 
ATOM   7559  C  CZ3 . TRP C 1 261 ? 279.132 253.331 250.947 1.00 16.13  ? 261 TRP C CZ3 1 
ATOM   7560  C  CH2 . TRP C 1 261 ? 279.935 252.691 249.997 1.00 20.10  ? 261 TRP C CH2 1 
ATOM   7561  N  N   . VAL C 1 262 ? 275.884 249.945 256.672 1.00 26.25  ? 262 VAL C N   1 
ATOM   7562  C  CA  . VAL C 1 262 ? 274.868 250.173 257.692 1.00 25.51  ? 262 VAL C CA  1 
ATOM   7563  C  C   . VAL C 1 262 ? 275.510 250.607 259.002 1.00 26.22  ? 262 VAL C C   1 
ATOM   7564  O  O   . VAL C 1 262 ? 274.991 251.484 259.702 1.00 30.79  ? 262 VAL C O   1 
ATOM   7565  C  CB  . VAL C 1 262 ? 274.003 248.914 257.876 1.00 26.31  ? 262 VAL C CB  1 
ATOM   7566  C  CG1 . VAL C 1 262 ? 273.369 248.906 259.257 1.00 26.23  ? 262 VAL C CG1 1 
ATOM   7567  C  CG2 . VAL C 1 262 ? 272.938 248.848 256.800 1.00 25.47  ? 262 VAL C CG2 1 
ATOM   7568  N  N   . ASN C 1 263 ? 276.642 250.001 259.360 1.00 26.33  ? 263 ASN C N   1 
ATOM   7569  C  CA  . ASN C 1 263 ? 277.218 250.240 260.677 1.00 25.98  ? 263 ASN C CA  1 
ATOM   7570  C  C   . ASN C 1 263 ? 277.940 251.576 260.761 1.00 29.71  ? 263 ASN C C   1 
ATOM   7571  O  O   . ASN C 1 263 ? 277.952 252.201 261.827 1.00 33.43  ? 263 ASN C O   1 
ATOM   7572  C  CB  . ASN C 1 263 ? 278.173 249.105 261.044 1.00 25.09  ? 263 ASN C CB  1 
ATOM   7573  C  CG  . ASN C 1 263 ? 277.444 247.846 261.458 1.00 29.92  ? 263 ASN C CG  1 
ATOM   7574  O  OD1 . ASN C 1 263 ? 276.584 247.875 262.336 1.00 35.33  ? 263 ASN C OD1 1 
ATOM   7575  N  ND2 . ASN C 1 263 ? 277.787 246.729 260.829 1.00 26.87  ? 263 ASN C ND2 1 
ATOM   7576  N  N   . ASP C 1 264 ? 278.540 252.028 259.661 1.00 27.49  ? 264 ASP C N   1 
ATOM   7577  C  CA  . ASP C 1 264 ? 279.323 253.257 259.699 1.00 27.74  ? 264 ASP C CA  1 
ATOM   7578  C  C   . ASP C 1 264 ? 278.441 254.489 259.860 1.00 30.95  ? 264 ASP C C   1 
ATOM   7579  O  O   . ASP C 1 264 ? 278.877 255.484 260.450 1.00 34.97  ? 264 ASP C O   1 
ATOM   7580  C  CB  . ASP C 1 264 ? 280.179 253.367 258.437 1.00 26.81  ? 264 ASP C CB  1 
ATOM   7581  C  CG  . ASP C 1 264 ? 281.345 252.395 258.437 1.00 32.21  ? 264 ASP C CG  1 
ATOM   7582  O  OD1 . ASP C 1 264 ? 281.645 251.827 259.507 1.00 35.17  ? 264 ASP C OD1 1 
ATOM   7583  O  OD2 . ASP C 1 264 ? 281.961 252.194 257.370 1.00 30.44  ? 264 ASP C OD2 1 
ATOM   7584  N  N   . PHE C 1 265 ? 277.206 254.448 259.359 1.00 29.32  ? 265 PHE C N   1 
ATOM   7585  C  CA  . PHE C 1 265 ? 276.337 255.623 259.310 1.00 28.89  ? 265 PHE C CA  1 
ATOM   7586  C  C   . PHE C 1 265 ? 274.981 255.310 259.927 1.00 30.80  ? 265 PHE C C   1 
ATOM   7587  O  O   . PHE C 1 265 ? 274.037 254.934 259.219 1.00 31.36  ? 265 PHE C O   1 
ATOM   7588  C  CB  . PHE C 1 265 ? 276.174 256.117 257.875 1.00 25.11  ? 265 PHE C CB  1 
ATOM   7589  C  CG  . PHE C 1 265 ? 277.465 256.207 257.123 1.00 31.34  ? 265 PHE C CG  1 
ATOM   7590  C  CD1 . PHE C 1 265 ? 278.324 257.273 257.318 1.00 30.17  ? 265 PHE C CD1 1 
ATOM   7591  C  CD2 . PHE C 1 265 ? 277.825 255.217 256.228 1.00 27.55  ? 265 PHE C CD2 1 
ATOM   7592  C  CE1 . PHE C 1 265 ? 279.516 257.352 256.630 1.00 26.06  ? 265 PHE C CE1 1 
ATOM   7593  C  CE2 . PHE C 1 265 ? 279.014 255.291 255.537 1.00 28.34  ? 265 PHE C CE2 1 
ATOM   7594  C  CZ  . PHE C 1 265 ? 279.862 256.360 255.740 1.00 24.85  ? 265 PHE C CZ  1 
ATOM   7595  N  N   . PRO C 1 266 ? 274.844 255.459 261.241 1.00 30.23  ? 266 PRO C N   1 
ATOM   7596  C  CA  . PRO C 1 266 ? 273.527 255.299 261.865 1.00 27.70  ? 266 PRO C CA  1 
ATOM   7597  C  C   . PRO C 1 266 ? 272.559 256.380 261.410 1.00 29.47  ? 266 PRO C C   1 
ATOM   7598  O  O   . PRO C 1 266 ? 272.945 257.513 261.117 1.00 33.54  ? 266 PRO C O   1 
ATOM   7599  C  CB  . PRO C 1 266 ? 273.822 255.416 263.367 1.00 26.48  ? 266 PRO C CB  1 
ATOM   7600  C  CG  . PRO C 1 266 ? 275.310 255.312 263.498 1.00 27.55  ? 266 PRO C CG  1 
ATOM   7601  C  CD  . PRO C 1 266 ? 275.879 255.820 262.220 1.00 26.37  ? 266 PRO C CD  1 
ATOM   7602  N  N   . ASN C 1 267 ? 271.279 256.012 261.353 1.00 31.92  ? 267 ASN C N   1 
ATOM   7603  C  CA  . ASN C 1 267 ? 270.210 256.935 260.971 1.00 28.16  ? 267 ASN C CA  1 
ATOM   7604  C  C   . ASN C 1 267 ? 270.362 257.404 259.524 1.00 29.28  ? 267 ASN C C   1 
ATOM   7605  O  O   . ASN C 1 267 ? 270.190 258.584 259.219 1.00 30.86  ? 267 ASN C O   1 
ATOM   7606  C  CB  . ASN C 1 267 ? 270.144 258.132 261.922 1.00 27.23  ? 267 ASN C CB  1 
ATOM   7607  C  CG  . ASN C 1 267 ? 269.696 257.743 263.316 1.00 35.16  ? 267 ASN C CG  1 
ATOM   7608  O  OD1 . ASN C 1 267 ? 268.827 256.889 263.484 1.00 40.56  ? 267 ASN C OD1 1 
ATOM   7609  N  ND2 . ASN C 1 267 ? 270.290 258.370 264.325 1.00 36.67  ? 267 ASN C ND2 1 
ATOM   7610  N  N   . ALA C 1 268 ? 270.683 256.474 258.629 1.00 29.83  ? 268 ALA C N   1 
ATOM   7611  C  CA  . ALA C 1 268 ? 270.796 256.766 257.209 1.00 26.19  ? 268 ALA C CA  1 
ATOM   7612  C  C   . ALA C 1 268 ? 270.267 255.582 256.415 1.00 29.90  ? 268 ALA C C   1 
ATOM   7613  O  O   . ALA C 1 268 ? 270.193 254.458 256.915 1.00 35.73  ? 268 ALA C O   1 
ATOM   7614  C  CB  . ALA C 1 268 ? 272.243 257.078 256.807 1.00 25.06  ? 268 ALA C CB  1 
ATOM   7615  N  N   . ARG C 1 269 ? 269.888 255.846 255.165 1.00 29.22  ? 269 ARG C N   1 
ATOM   7616  C  CA  . ARG C 1 269 ? 269.403 254.803 254.264 1.00 29.21  ? 269 ARG C CA  1 
ATOM   7617  C  C   . ARG C 1 269 ? 270.580 254.318 253.422 1.00 31.11  ? 269 ARG C C   1 
ATOM   7618  O  O   . ARG C 1 269 ? 270.733 254.663 252.252 1.00 37.91  ? 269 ARG C O   1 
ATOM   7619  C  CB  . ARG C 1 269 ? 268.257 255.321 253.400 1.00 28.75  ? 269 ARG C CB  1 
ATOM   7620  C  CG  . ARG C 1 269 ? 266.920 255.370 254.113 1.00 35.91  ? 269 ARG C CG  1 
ATOM   7621  C  CD  . ARG C 1 269 ? 265.769 255.455 253.128 1.00 35.29  ? 269 ARG C CD  1 
ATOM   7622  N  NE  . ARG C 1 269 ? 265.842 254.415 252.110 1.00 33.42  ? 269 ARG C NE  1 
ATOM   7623  C  CZ  . ARG C 1 269 ? 265.216 253.249 252.188 1.00 35.88  ? 269 ARG C CZ  1 
ATOM   7624  N  NH1 . ARG C 1 269 ? 264.462 252.938 253.229 1.00 34.03  ? 269 ARG C NH1 1 
ATOM   7625  N  NH2 . ARG C 1 269 ? 265.351 252.373 251.198 1.00 35.88  ? 269 ARG C NH2 1 
ATOM   7626  N  N   . THR C 1 270 ? 271.425 253.499 254.045 1.00 30.44  ? 270 THR C N   1 
ATOM   7627  C  CA  . THR C 1 270 ? 272.629 252.988 253.401 1.00 29.54  ? 270 THR C CA  1 
ATOM   7628  C  C   . THR C 1 270 ? 272.608 251.474 253.233 1.00 29.41  ? 270 THR C C   1 
ATOM   7629  O  O   . THR C 1 270 ? 273.617 250.895 252.815 1.00 34.95  ? 270 THR C O   1 
ATOM   7630  C  CB  . THR C 1 270 ? 273.872 253.411 254.190 1.00 27.72  ? 270 THR C CB  1 
ATOM   7631  O  OG1 . THR C 1 270 ? 273.715 253.049 255.567 1.00 29.04  ? 270 THR C OG1 1 
ATOM   7632  C  CG2 . THR C 1 270 ? 274.070 254.912 254.095 1.00 26.14  ? 270 THR C CG2 1 
ATOM   7633  N  N   . GLU C 1 271 ? 271.490 250.816 253.547 1.00 27.72  ? 271 GLU C N   1 
ATOM   7634  C  CA  . GLU C 1 271 ? 271.388 249.376 253.349 1.00 27.05  ? 271 GLU C CA  1 
ATOM   7635  C  C   . GLU C 1 271 ? 271.385 248.997 251.874 1.00 29.22  ? 271 GLU C C   1 
ATOM   7636  O  O   . GLU C 1 271 ? 271.753 247.867 251.532 1.00 33.86  ? 271 GLU C O   1 
ATOM   7637  C  CB  . GLU C 1 271 ? 270.129 248.843 254.033 1.00 28.42  ? 271 GLU C CB  1 
ATOM   7638  C  CG  . GLU C 1 271 ? 268.848 249.546 253.612 1.00 35.31  ? 271 GLU C CG  1 
ATOM   7639  C  CD  . GLU C 1 271 ? 268.479 250.698 254.529 1.00 40.78  ? 271 GLU C CD  1 
ATOM   7640  O  OE1 . GLU C 1 271 ? 269.354 251.169 255.285 1.00 39.19  ? 271 GLU C OE1 1 
ATOM   7641  O  OE2 . GLU C 1 271 ? 267.310 251.134 254.494 1.00 39.60  ? 271 GLU C OE2 1 
ATOM   7642  N  N   . ILE C 1 272 ? 270.986 249.918 250.995 1.00 29.12  ? 272 ILE C N   1 
ATOM   7643  C  CA  . ILE C 1 272 ? 271.032 249.647 249.563 1.00 30.40  ? 272 ILE C CA  1 
ATOM   7644  C  C   . ILE C 1 272 ? 272.454 249.313 249.135 1.00 29.66  ? 272 ILE C C   1 
ATOM   7645  O  O   . ILE C 1 272 ? 272.678 248.416 248.314 1.00 30.56  ? 272 ILE C O   1 
ATOM   7646  C  CB  . ILE C 1 272 ? 270.468 250.844 248.776 1.00 28.90  ? 272 ILE C CB  1 
ATOM   7647  C  CG1 . ILE C 1 272 ? 270.386 250.516 247.285 1.00 28.11  ? 272 ILE C CG1 1 
ATOM   7648  C  CG2 . ILE C 1 272 ? 271.315 252.085 249.007 1.00 29.11  ? 272 ILE C CG2 1 
ATOM   7649  C  CD1 . ILE C 1 272 ? 269.553 249.301 246.979 1.00 32.29  ? 272 ILE C CD1 1 
ATOM   7650  N  N   . TYR C 1 273 ? 273.437 250.028 249.684 1.00 29.44  ? 273 TYR C N   1 
ATOM   7651  C  CA  . TYR C 1 273 ? 274.828 249.745 249.350 1.00 24.82  ? 273 TYR C CA  1 
ATOM   7652  C  C   . TYR C 1 273 ? 275.293 248.449 249.997 1.00 25.09  ? 273 TYR C C   1 
ATOM   7653  O  O   . TYR C 1 273 ? 276.058 247.688 249.395 1.00 27.46  ? 273 TYR C O   1 
ATOM   7654  C  CB  . TYR C 1 273 ? 275.710 250.914 249.778 1.00 20.01  ? 273 TYR C CB  1 
ATOM   7655  C  CG  . TYR C 1 273 ? 275.196 252.244 249.290 1.00 26.61  ? 273 TYR C CG  1 
ATOM   7656  C  CD1 . TYR C 1 273 ? 275.019 252.487 247.936 1.00 25.14  ? 273 TYR C CD1 1 
ATOM   7657  C  CD2 . TYR C 1 273 ? 274.873 253.253 250.184 1.00 29.62  ? 273 TYR C CD2 1 
ATOM   7658  C  CE1 . TYR C 1 273 ? 274.545 253.699 247.488 1.00 23.32  ? 273 TYR C CE1 1 
ATOM   7659  C  CE2 . TYR C 1 273 ? 274.398 254.468 249.745 1.00 30.32  ? 273 TYR C CE2 1 
ATOM   7660  C  CZ  . TYR C 1 273 ? 274.235 254.685 248.396 1.00 28.39  ? 273 TYR C CZ  1 
ATOM   7661  O  OH  . TYR C 1 273 ? 273.762 255.897 247.957 1.00 32.35  ? 273 TYR C OH  1 
ATOM   7662  N  N   . THR C 1 274 ? 274.840 248.179 251.221 1.00 24.20  ? 274 THR C N   1 
ATOM   7663  C  CA  . THR C 1 274 ? 275.130 246.898 251.851 1.00 22.98  ? 274 THR C CA  1 
ATOM   7664  C  C   . THR C 1 274 ? 274.588 245.734 251.038 1.00 24.49  ? 274 THR C C   1 
ATOM   7665  O  O   . THR C 1 274 ? 275.105 244.618 251.150 1.00 33.34  ? 274 THR C O   1 
ATOM   7666  C  CB  . THR C 1 274 ? 274.549 246.862 253.268 1.00 22.92  ? 274 THR C CB  1 
ATOM   7667  O  OG1 . THR C 1 274 ? 275.405 247.586 254.158 1.00 26.58  ? 274 THR C OG1 1 
ATOM   7668  C  CG2 . THR C 1 274 ? 274.415 245.430 253.758 1.00 18.68  ? 274 THR C CG2 1 
ATOM   7669  N  N   . ARG C 1 275 ? 273.566 245.967 250.217 1.00 27.89  ? 275 ARG C N   1 
ATOM   7670  C  CA  . ARG C 1 275 ? 272.993 244.911 249.393 1.00 27.54  ? 275 ARG C CA  1 
ATOM   7671  C  C   . ARG C 1 275 ? 273.562 244.851 247.982 1.00 32.12  ? 275 ARG C C   1 
ATOM   7672  O  O   . ARG C 1 275 ? 273.641 243.759 247.411 1.00 37.31  ? 275 ARG C O   1 
ATOM   7673  C  CB  . ARG C 1 275 ? 271.471 245.069 249.308 1.00 32.80  ? 275 ARG C CB  1 
ATOM   7674  C  CG  . ARG C 1 275 ? 270.759 244.993 250.647 1.00 32.10  ? 275 ARG C CG  1 
ATOM   7675  C  CD  . ARG C 1 275 ? 269.260 245.171 250.480 1.00 34.20  ? 275 ARG C CD  1 
ATOM   7676  N  NE  . ARG C 1 275 ? 268.656 244.066 249.746 1.00 39.52  ? 275 ARG C NE  1 
ATOM   7677  C  CZ  . ARG C 1 275 ? 267.493 244.136 249.114 1.00 43.03  ? 275 ARG C CZ  1 
ATOM   7678  N  NH1 . ARG C 1 275 ? 266.774 245.246 249.110 1.00 36.75  ? 275 ARG C NH1 1 
ATOM   7679  N  NH2 . ARG C 1 275 ? 267.041 243.065 248.468 1.00 44.97  ? 275 ARG C NH2 1 
ATOM   7680  N  N   . MET C 1 276 ? 273.959 245.983 247.396 1.00 29.69  ? 276 MET C N   1 
ATOM   7681  C  CA  . MET C 1 276 ? 274.299 246.022 245.980 1.00 29.86  ? 276 MET C CA  1 
ATOM   7682  C  C   . MET C 1 276 ? 275.743 246.378 245.661 1.00 30.41  ? 276 MET C C   1 
ATOM   7683  O  O   . MET C 1 276 ? 276.205 246.035 244.569 1.00 33.78  ? 276 MET C O   1 
ATOM   7684  C  CB  . MET C 1 276 ? 273.395 247.020 245.239 1.00 33.87  ? 276 MET C CB  1 
ATOM   7685  C  CG  . MET C 1 276 ? 271.995 247.131 245.800 1.00 43.75  ? 276 MET C CG  1 
ATOM   7686  S  SD  . MET C 1 276 ? 270.837 246.037 244.961 1.00 82.04  ? 276 MET C SD  1 
ATOM   7687  C  CE  . MET C 1 276 ? 270.467 247.004 243.501 1.00 65.32  ? 276 MET C CE  1 
ATOM   7688  N  N   . TYR C 1 277 ? 276.467 247.052 246.556 1.00 26.41  ? 277 TYR C N   1 
ATOM   7689  C  CA  . TYR C 1 277 ? 277.748 247.633 246.161 1.00 24.60  ? 277 TYR C CA  1 
ATOM   7690  C  C   . TYR C 1 277 ? 278.717 246.566 245.666 1.00 26.50  ? 277 TYR C C   1 
ATOM   7691  O  O   . TYR C 1 277 ? 279.344 246.723 244.612 1.00 29.45  ? 277 TYR C O   1 
ATOM   7692  C  CB  . TYR C 1 277 ? 278.358 248.418 247.320 1.00 23.57  ? 277 TYR C CB  1 
ATOM   7693  C  CG  . TYR C 1 277 ? 279.597 249.188 246.927 1.00 21.17  ? 277 TYR C CG  1 
ATOM   7694  C  CD1 . TYR C 1 277 ? 279.505 250.351 246.176 1.00 22.76  ? 277 TYR C CD1 1 
ATOM   7695  C  CD2 . TYR C 1 277 ? 280.860 248.747 247.297 1.00 20.70  ? 277 TYR C CD2 1 
ATOM   7696  C  CE1 . TYR C 1 277 ? 280.633 251.056 245.811 1.00 22.24  ? 277 TYR C CE1 1 
ATOM   7697  C  CE2 . TYR C 1 277 ? 281.992 249.444 246.938 1.00 19.62  ? 277 TYR C CE2 1 
ATOM   7698  C  CZ  . TYR C 1 277 ? 281.874 250.598 246.194 1.00 23.21  ? 277 TYR C CZ  1 
ATOM   7699  O  OH  . TYR C 1 277 ? 283.000 251.298 245.833 1.00 19.28  ? 277 TYR C OH  1 
ATOM   7700  N  N   . PHE C 1 278 ? 278.852 245.470 246.409 1.00 27.19  ? 278 PHE C N   1 
ATOM   7701  C  CA  . PHE C 1 278 ? 279.748 244.389 246.017 1.00 25.61  ? 278 PHE C CA  1 
ATOM   7702  C  C   . PHE C 1 278 ? 279.098 243.381 245.077 1.00 30.32  ? 278 PHE C C   1 
ATOM   7703  O  O   . PHE C 1 278 ? 279.803 242.529 244.529 1.00 33.45  ? 278 PHE C O   1 
ATOM   7704  C  CB  . PHE C 1 278 ? 280.274 243.661 247.262 1.00 23.80  ? 278 PHE C CB  1 
ATOM   7705  C  CG  . PHE C 1 278 ? 281.335 242.635 246.963 1.00 25.18  ? 278 PHE C CG  1 
ATOM   7706  C  CD1 . PHE C 1 278 ? 282.497 242.992 246.301 1.00 23.04  ? 278 PHE C CD1 1 
ATOM   7707  C  CD2 . PHE C 1 278 ? 281.167 241.314 247.341 1.00 23.15  ? 278 PHE C CD2 1 
ATOM   7708  C  CE1 . PHE C 1 278 ? 283.469 242.053 246.021 1.00 22.99  ? 278 PHE C CE1 1 
ATOM   7709  C  CE2 . PHE C 1 278 ? 282.137 240.371 247.064 1.00 22.93  ? 278 PHE C CE2 1 
ATOM   7710  C  CZ  . PHE C 1 278 ? 283.290 240.741 246.404 1.00 21.06  ? 278 PHE C CZ  1 
ATOM   7711  N  N   . ASN C 1 279 ? 277.785 243.461 244.867 1.00 33.48  ? 279 ASN C N   1 
ATOM   7712  C  CA  . ASN C 1 279 ? 277.064 242.465 244.087 1.00 34.87  ? 279 ASN C CA  1 
ATOM   7713  C  C   . ASN C 1 279 ? 276.446 243.009 242.807 1.00 42.27  ? 279 ASN C C   1 
ATOM   7714  O  O   . ASN C 1 279 ? 275.823 242.240 242.067 1.00 49.83  ? 279 ASN C O   1 
ATOM   7715  C  CB  . ASN C 1 279 ? 275.965 241.823 244.943 1.00 35.15  ? 279 ASN C CB  1 
ATOM   7716  C  CG  . ASN C 1 279 ? 276.409 241.581 246.370 1.00 39.84  ? 279 ASN C CG  1 
ATOM   7717  O  OD1 . ASN C 1 279 ? 277.023 240.560 246.676 1.00 43.40  ? 279 ASN C OD1 1 
ATOM   7718  N  ND2 . ASN C 1 279 ? 276.105 242.525 247.251 1.00 35.71  ? 279 ASN C ND2 1 
ATOM   7719  N  N   . HIS C 1 280 ? 276.587 244.295 242.526 1.00 38.10  ? 280 HIS C N   1 
ATOM   7720  C  CA  . HIS C 1 280 ? 275.976 244.850 241.325 1.00 36.75  ? 280 HIS C CA  1 
ATOM   7721  C  C   . HIS C 1 280 ? 277.012 244.981 240.222 1.00 41.18  ? 280 HIS C C   1 
ATOM   7722  O  O   . HIS C 1 280 ? 278.114 245.486 240.475 1.00 42.17  ? 280 HIS C O   1 
ATOM   7723  C  CB  . HIS C 1 280 ? 275.358 246.212 241.621 1.00 39.27  ? 280 HIS C CB  1 
ATOM   7724  C  CG  . HIS C 1 280 ? 274.374 246.666 240.590 1.00 47.41  ? 280 HIS C CG  1 
ATOM   7725  N  ND1 . HIS C 1 280 ? 274.670 246.708 239.245 1.00 46.14  ? 280 HIS C ND1 1 
ATOM   7726  C  CD2 . HIS C 1 280 ? 273.094 247.092 240.706 1.00 54.07  ? 280 HIS C CD2 1 
ATOM   7727  C  CE1 . HIS C 1 280 ? 273.617 247.143 238.577 1.00 46.02  ? 280 HIS C CE1 1 
ATOM   7728  N  NE2 . HIS C 1 280 ? 272.647 247.383 239.440 1.00 53.67  ? 280 HIS C NE2 1 
ATOM   7729  N  N   . PRO C 1 281 ? 276.710 244.543 238.999 1.00 45.19  ? 281 PRO C N   1 
ATOM   7730  C  CA  . PRO C 1 281 ? 277.700 244.653 237.917 1.00 40.03  ? 281 PRO C CA  1 
ATOM   7731  C  C   . PRO C 1 281 ? 278.079 246.082 237.582 1.00 36.51  ? 281 PRO C C   1 
ATOM   7732  O  O   . PRO C 1 281 ? 279.149 246.302 237.003 1.00 38.23  ? 281 PRO C O   1 
ATOM   7733  C  CB  . PRO C 1 281 ? 277.009 243.963 236.732 1.00 44.18  ? 281 PRO C CB  1 
ATOM   7734  C  CG  . PRO C 1 281 ? 275.892 243.172 237.331 1.00 51.31  ? 281 PRO C CG  1 
ATOM   7735  C  CD  . PRO C 1 281 ? 275.460 243.916 238.544 1.00 50.40  ? 281 PRO C CD  1 
ATOM   7736  N  N   . GLY C 1 282 ? 277.238 247.062 237.917 1.00 38.63  ? 282 GLY C N   1 
ATOM   7737  C  CA  . GLY C 1 282 ? 277.578 248.447 237.652 1.00 36.37  ? 282 GLY C CA  1 
ATOM   7738  C  C   . GLY C 1 282 ? 278.648 249.000 238.565 1.00 34.83  ? 282 GLY C C   1 
ATOM   7739  O  O   . GLY C 1 282 ? 279.283 250.003 238.224 1.00 39.00  ? 282 GLY C O   1 
ATOM   7740  N  N   . TYR C 1 283 ? 278.864 248.368 239.715 1.00 32.33  ? 283 TYR C N   1 
ATOM   7741  C  CA  . TYR C 1 283 ? 279.893 248.772 240.659 1.00 25.19  ? 283 TYR C CA  1 
ATOM   7742  C  C   . TYR C 1 283 ? 281.183 247.984 240.482 1.00 26.69  ? 283 TYR C C   1 
ATOM   7743  O  O   . TYR C 1 283 ? 282.053 248.038 241.355 1.00 28.86  ? 283 TYR C O   1 
ATOM   7744  C  CB  . TYR C 1 283 ? 279.384 248.613 242.091 1.00 25.59  ? 283 TYR C CB  1 
ATOM   7745  C  CG  . TYR C 1 283 ? 278.377 249.654 242.514 1.00 27.07  ? 283 TYR C CG  1 
ATOM   7746  C  CD1 . TYR C 1 283 ? 278.657 251.008 242.397 1.00 24.12  ? 283 TYR C CD1 1 
ATOM   7747  C  CD2 . TYR C 1 283 ? 277.147 249.283 243.038 1.00 29.52  ? 283 TYR C CD2 1 
ATOM   7748  C  CE1 . TYR C 1 283 ? 277.739 251.962 242.787 1.00 25.50  ? 283 TYR C CE1 1 
ATOM   7749  C  CE2 . TYR C 1 283 ? 276.224 250.229 243.432 1.00 27.26  ? 283 TYR C CE2 1 
ATOM   7750  C  CZ  . TYR C 1 283 ? 276.526 251.567 243.303 1.00 30.95  ? 283 TYR C CZ  1 
ATOM   7751  O  OH  . TYR C 1 283 ? 275.610 252.515 243.693 1.00 33.63  ? 283 TYR C OH  1 
ATOM   7752  N  N   . ASP C 1 284 ? 281.325 247.257 239.372 1.00 25.83  ? 284 ASP C N   1 
ATOM   7753  C  CA  . ASP C 1 284 ? 282.472 246.369 239.206 1.00 23.37  ? 284 ASP C CA  1 
ATOM   7754  C  C   . ASP C 1 284 ? 283.786 247.137 239.257 1.00 25.59  ? 284 ASP C C   1 
ATOM   7755  O  O   . ASP C 1 284 ? 284.764 246.668 239.850 1.00 26.39  ? 284 ASP C O   1 
ATOM   7756  C  CB  . ASP C 1 284 ? 282.352 245.602 237.890 1.00 26.21  ? 284 ASP C CB  1 
ATOM   7757  C  CG  . ASP C 1 284 ? 281.745 244.227 238.069 1.00 37.39  ? 284 ASP C CG  1 
ATOM   7758  O  OD1 . ASP C 1 284 ? 281.293 243.916 239.189 1.00 37.17  ? 284 ASP C OD1 1 
ATOM   7759  O  OD2 . ASP C 1 284 ? 281.721 243.455 237.089 1.00 46.25  ? 284 ASP C OD2 1 
ATOM   7760  N  N   . ASP C 1 285 ? 283.833 248.316 238.642 1.00 29.35  ? 285 ASP C N   1 
ATOM   7761  C  CA  . ASP C 1 285 ? 285.046 249.118 238.592 1.00 18.93  ? 285 ASP C CA  1 
ATOM   7762  C  C   . ASP C 1 285 ? 285.146 250.111 239.741 1.00 20.66  ? 285 ASP C C   1 
ATOM   7763  O  O   . ASP C 1 285 ? 286.069 250.930 239.757 1.00 26.29  ? 285 ASP C O   1 
ATOM   7764  C  CB  . ASP C 1 285 ? 285.133 249.860 237.258 1.00 22.49  ? 285 ASP C CB  1 
ATOM   7765  C  CG  . ASP C 1 285 ? 285.217 248.920 236.077 1.00 32.15  ? 285 ASP C CG  1 
ATOM   7766  O  OD1 . ASP C 1 285 ? 285.410 247.707 236.298 1.00 36.48  ? 285 ASP C OD1 1 
ATOM   7767  O  OD2 . ASP C 1 285 ? 285.096 249.392 234.928 1.00 38.80  ? 285 ASP C OD2 1 
ATOM   7768  N  N   . TYR C 1 286 ? 284.218 250.071 240.681 1.00 19.74  ? 286 TYR C N   1 
ATOM   7769  C  CA  . TYR C 1 286 ? 284.356 250.888 241.872 1.00 18.48  ? 286 TYR C CA  1 
ATOM   7770  C  C   . TYR C 1 286 ? 285.275 250.197 242.879 1.00 18.78  ? 286 TYR C C   1 
ATOM   7771  O  O   . TYR C 1 286 ? 285.333 248.966 242.934 1.00 19.56  ? 286 TYR C O   1 
ATOM   7772  C  CB  . TYR C 1 286 ? 282.995 251.151 242.506 1.00 20.55  ? 286 TYR C CB  1 
ATOM   7773  C  CG  . TYR C 1 286 ? 282.103 252.081 241.712 1.00 19.64  ? 286 TYR C CG  1 
ATOM   7774  C  CD1 . TYR C 1 286 ? 281.830 251.844 240.372 1.00 22.09  ? 286 TYR C CD1 1 
ATOM   7775  C  CD2 . TYR C 1 286 ? 281.531 253.196 242.307 1.00 20.13  ? 286 TYR C CD2 1 
ATOM   7776  C  CE1 . TYR C 1 286 ? 281.017 252.690 239.649 1.00 25.33  ? 286 TYR C CE1 1 
ATOM   7777  C  CE2 . TYR C 1 286 ? 280.716 254.048 241.592 1.00 20.73  ? 286 TYR C CE2 1 
ATOM   7778  C  CZ  . TYR C 1 286 ? 280.461 253.790 240.263 1.00 26.88  ? 286 TYR C CZ  1 
ATOM   7779  O  OH  . TYR C 1 286 ? 279.649 254.635 239.544 1.00 32.71  ? 286 TYR C OH  1 
ATOM   7780  N  N   . PRO C 1 287 ? 286.005 250.969 243.680 1.00 19.08  ? 287 PRO C N   1 
ATOM   7781  C  CA  . PRO C 1 287 ? 286.923 250.360 244.649 1.00 19.02  ? 287 PRO C CA  1 
ATOM   7782  C  C   . PRO C 1 287 ? 286.184 249.482 245.648 1.00 16.92  ? 287 PRO C C   1 
ATOM   7783  O  O   . PRO C 1 287 ? 285.069 249.791 246.072 1.00 18.02  ? 287 PRO C O   1 
ATOM   7784  C  CB  . PRO C 1 287 ? 287.572 251.569 245.333 1.00 17.78  ? 287 PRO C CB  1 
ATOM   7785  C  CG  . PRO C 1 287 ? 286.646 252.709 245.072 1.00 15.48  ? 287 PRO C CG  1 
ATOM   7786  C  CD  . PRO C 1 287 ? 286.028 252.438 243.739 1.00 17.87  ? 287 PRO C CD  1 
ATOM   7787  N  N   . VAL C 1 288 ? 286.822 248.379 246.023 1.00 16.66  ? 288 VAL C N   1 
ATOM   7788  C  CA  . VAL C 1 288 ? 286.268 247.471 247.020 1.00 15.90  ? 288 VAL C CA  1 
ATOM   7789  C  C   . VAL C 1 288 ? 286.457 248.079 248.403 1.00 21.11  ? 288 VAL C C   1 
ATOM   7790  O  O   . VAL C 1 288 ? 287.545 248.562 248.740 1.00 25.44  ? 288 VAL C O   1 
ATOM   7791  C  CB  . VAL C 1 288 ? 286.927 246.085 246.923 1.00 15.46  ? 288 VAL C CB  1 
ATOM   7792  C  CG1 . VAL C 1 288 ? 288.390 246.156 247.330 1.00 12.07  ? 288 VAL C CG1 1 
ATOM   7793  C  CG2 . VAL C 1 288 ? 286.173 245.067 247.772 1.00 15.33  ? 288 VAL C CG2 1 
ATOM   7794  N  N   . VAL C 1 289 ? 285.397 248.061 249.205 1.00 19.81  ? 289 VAL C N   1 
ATOM   7795  C  CA  . VAL C 1 289 ? 285.455 248.567 250.571 1.00 19.46  ? 289 VAL C CA  1 
ATOM   7796  C  C   . VAL C 1 289 ? 285.069 247.445 251.522 1.00 19.98  ? 289 VAL C C   1 
ATOM   7797  O  O   . VAL C 1 289 ? 284.781 246.324 251.091 1.00 23.75  ? 289 VAL C O   1 
ATOM   7798  C  CB  . VAL C 1 289 ? 284.548 249.796 250.758 1.00 17.82  ? 289 VAL C CB  1 
ATOM   7799  C  CG1 . VAL C 1 289 ? 285.128 250.994 250.030 1.00 16.67  ? 289 VAL C CG1 1 
ATOM   7800  C  CG2 . VAL C 1 289 ? 283.144 249.498 250.265 1.00 16.81  ? 289 VAL C CG2 1 
ATOM   7801  N  N   . GLY C 1 290 ? 285.067 247.734 252.820 1.00 18.68  ? 290 GLY C N   1 
ATOM   7802  C  CA  . GLY C 1 290 ? 284.762 246.711 253.798 1.00 16.98  ? 290 GLY C CA  1 
ATOM   7803  C  C   . GLY C 1 290 ? 285.829 245.655 253.943 1.00 22.00  ? 290 GLY C C   1 
ATOM   7804  O  O   . GLY C 1 290 ? 285.564 244.591 254.507 1.00 24.63  ? 290 GLY C O   1 
ATOM   7805  N  N   . ILE C 1 291 ? 287.033 245.920 253.446 1.00 21.65  ? 291 ILE C N   1 
ATOM   7806  C  CA  . ILE C 1 291 ? 288.152 244.991 253.529 1.00 15.96  ? 291 ILE C CA  1 
ATOM   7807  C  C   . ILE C 1 291 ? 289.038 245.414 254.690 1.00 18.58  ? 291 ILE C C   1 
ATOM   7808  O  O   . ILE C 1 291 ? 289.454 246.576 254.772 1.00 25.73  ? 291 ILE C O   1 
ATOM   7809  C  CB  . ILE C 1 291 ? 288.947 244.956 252.213 1.00 16.81  ? 291 ILE C CB  1 
ATOM   7810  C  CG1 . ILE C 1 291 ? 288.019 244.645 251.038 1.00 16.65  ? 291 ILE C CG1 1 
ATOM   7811  C  CG2 . ILE C 1 291 ? 290.083 243.950 252.291 1.00 14.39  ? 291 ILE C CG2 1 
ATOM   7812  C  CD1 . ILE C 1 291 ? 287.204 243.384 251.217 1.00 16.06  ? 291 ILE C CD1 1 
ATOM   7813  N  N   . SER C 1 292 ? 289.314 244.483 255.592 1.00 17.39  ? 292 SER C N   1 
ATOM   7814  C  CA  . SER C 1 292 ? 290.190 244.765 256.715 1.00 16.36  ? 292 SER C CA  1 
ATOM   7815  C  C   . SER C 1 292 ? 291.652 244.593 256.308 1.00 16.14  ? 292 SER C C   1 
ATOM   7816  O  O   . SER C 1 292 ? 291.975 244.102 255.225 1.00 18.46  ? 292 SER C O   1 
ATOM   7817  C  CB  . SER C 1 292 ? 289.842 243.868 257.903 1.00 15.92  ? 292 SER C CB  1 
ATOM   7818  O  OG  . SER C 1 292 ? 290.311 242.548 257.708 1.00 23.50  ? 292 SER C OG  1 
ATOM   7819  N  N   . TRP C 1 293 ? 292.543 245.018 257.203 1.00 16.58  ? 293 TRP C N   1 
ATOM   7820  C  CA  . TRP C 1 293 ? 293.975 244.951 256.931 1.00 13.18  ? 293 TRP C CA  1 
ATOM   7821  C  C   . TRP C 1 293 ? 294.430 243.508 256.727 1.00 16.58  ? 293 TRP C C   1 
ATOM   7822  O  O   . TRP C 1 293 ? 295.219 243.215 255.818 1.00 19.64  ? 293 TRP C O   1 
ATOM   7823  C  CB  . TRP C 1 293 ? 294.725 245.626 258.082 1.00 12.97  ? 293 TRP C CB  1 
ATOM   7824  C  CG  . TRP C 1 293 ? 296.196 245.807 257.900 1.00 13.76  ? 293 TRP C CG  1 
ATOM   7825  C  CD1 . TRP C 1 293 ? 296.823 246.835 257.265 1.00 13.10  ? 293 TRP C CD1 1 
ATOM   7826  C  CD2 . TRP C 1 293 ? 297.230 244.960 258.410 1.00 15.31  ? 293 TRP C CD2 1 
ATOM   7827  N  NE1 . TRP C 1 293 ? 298.184 246.669 257.325 1.00 14.67  ? 293 TRP C NE1 1 
ATOM   7828  C  CE2 . TRP C 1 293 ? 298.459 245.525 258.025 1.00 15.68  ? 293 TRP C CE2 1 
ATOM   7829  C  CE3 . TRP C 1 293 ? 297.235 243.773 259.147 1.00 13.89  ? 293 TRP C CE3 1 
ATOM   7830  C  CZ2 . TRP C 1 293 ? 299.680 244.944 258.351 1.00 16.83  ? 293 TRP C CZ2 1 
ATOM   7831  C  CZ3 . TRP C 1 293 ? 298.446 243.197 259.466 1.00 15.22  ? 293 TRP C CZ3 1 
ATOM   7832  C  CH2 . TRP C 1 293 ? 299.652 243.783 259.071 1.00 16.32  ? 293 TRP C CH2 1 
ATOM   7833  N  N   . GLU C 1 294 ? 293.927 242.590 257.556 1.00 16.42  ? 294 GLU C N   1 
ATOM   7834  C  CA  . GLU C 1 294 ? 294.275 241.179 257.413 1.00 17.10  ? 294 GLU C CA  1 
ATOM   7835  C  C   . GLU C 1 294 ? 293.788 240.619 256.082 1.00 17.91  ? 294 GLU C C   1 
ATOM   7836  O  O   . GLU C 1 294 ? 294.494 239.843 255.428 1.00 22.75  ? 294 GLU C O   1 
ATOM   7837  C  CB  . GLU C 1 294 ? 293.687 240.383 258.577 1.00 20.05  ? 294 GLU C CB  1 
ATOM   7838  C  CG  . GLU C 1 294 ? 294.097 240.894 259.946 1.00 20.87  ? 294 GLU C CG  1 
ATOM   7839  C  CD  . GLU C 1 294 ? 293.168 240.421 261.044 1.00 31.66  ? 294 GLU C CD  1 
ATOM   7840  O  OE1 . GLU C 1 294 ? 292.133 239.803 260.721 1.00 39.07  ? 294 GLU C OE1 1 
ATOM   7841  O  OE2 . GLU C 1 294 ? 293.465 240.674 262.229 1.00 29.51  ? 294 GLU C OE2 1 
ATOM   7842  N  N   . GLN C 1 295 ? 292.576 240.993 255.669 1.00 18.60  ? 295 GLN C N   1 
ATOM   7843  C  CA  . GLN C 1 295 ? 292.061 240.527 254.386 1.00 18.26  ? 295 GLN C CA  1 
ATOM   7844  C  C   . GLN C 1 295 ? 292.873 241.090 253.226 1.00 16.43  ? 295 GLN C C   1 
ATOM   7845  O  O   . GLN C 1 295 ? 293.093 240.401 252.225 1.00 19.46  ? 295 GLN C O   1 
ATOM   7846  C  CB  . GLN C 1 295 ? 290.583 240.891 254.248 1.00 17.23  ? 295 GLN C CB  1 
ATOM   7847  C  CG  . GLN C 1 295 ? 289.693 240.227 255.286 1.00 18.35  ? 295 GLN C CG  1 
ATOM   7848  C  CD  . GLN C 1 295 ? 288.274 240.757 255.280 1.00 20.52  ? 295 GLN C CD  1 
ATOM   7849  O  OE1 . GLN C 1 295 ? 288.049 241.965 255.279 1.00 21.59  ? 295 GLN C OE1 1 
ATOM   7850  N  NE2 . GLN C 1 295 ? 287.307 239.849 255.285 1.00 21.55  ? 295 GLN C NE2 1 
ATOM   7851  N  N   . ALA C 1 296 ? 293.325 242.340 253.339 1.00 16.25  ? 296 ALA C N   1 
ATOM   7852  C  CA  . ALA C 1 296 ? 294.176 242.911 252.300 1.00 14.39  ? 296 ALA C CA  1 
ATOM   7853  C  C   . ALA C 1 296 ? 295.504 242.169 252.209 1.00 21.56  ? 296 ALA C C   1 
ATOM   7854  O  O   . ALA C 1 296 ? 296.003 241.903 251.108 1.00 25.93  ? 296 ALA C O   1 
ATOM   7855  C  CB  . ALA C 1 296 ? 294.403 244.399 252.563 1.00 11.04  ? 296 ALA C CB  1 
ATOM   7856  N  N   . GLN C 1 297 ? 296.093 241.824 253.356 1.00 18.84  ? 297 GLN C N   1 
ATOM   7857  C  CA  . GLN C 1 297 ? 297.326 241.041 253.340 1.00 18.73  ? 297 GLN C CA  1 
ATOM   7858  C  C   . GLN C 1 297 ? 297.103 239.667 252.718 1.00 20.81  ? 297 GLN C C   1 
ATOM   7859  O  O   . GLN C 1 297 ? 297.941 239.178 251.949 1.00 27.95  ? 297 GLN C O   1 
ATOM   7860  C  CB  . GLN C 1 297 ? 297.877 240.910 254.757 1.00 20.98  ? 297 GLN C CB  1 
ATOM   7861  C  CG  . GLN C 1 297 ? 298.484 242.189 255.294 1.00 22.21  ? 297 GLN C CG  1 
ATOM   7862  C  CD  . GLN C 1 297 ? 299.608 241.929 256.268 1.00 35.63  ? 297 GLN C CD  1 
ATOM   7863  O  OE1 . GLN C 1 297 ? 300.583 242.676 256.320 1.00 39.08  ? 297 GLN C OE1 1 
ATOM   7864  N  NE2 . GLN C 1 297 ? 299.478 240.865 257.050 1.00 34.98  ? 297 GLN C NE2 1 
ATOM   7865  N  N   . ALA C 1 298 ? 295.980 239.024 253.046 1.00 20.79  ? 298 ALA C N   1 
ATOM   7866  C  CA  . ALA C 1 298 ? 295.667 237.731 252.446 1.00 16.31  ? 298 ALA C CA  1 
ATOM   7867  C  C   . ALA C 1 298 ? 295.494 237.850 250.936 1.00 19.18  ? 298 ALA C C   1 
ATOM   7868  O  O   . ALA C 1 298 ? 295.947 236.982 250.179 1.00 22.67  ? 298 ALA C O   1 
ATOM   7869  C  CB  . ALA C 1 298 ? 294.411 237.146 253.089 1.00 15.44  ? 298 ALA C CB  1 
ATOM   7870  N  N   . PHE C 1 299 ? 294.836 238.918 250.478 1.00 19.79  ? 299 PHE C N   1 
ATOM   7871  C  CA  . PHE C 1 299 ? 294.688 239.142 249.044 1.00 16.41  ? 299 PHE C CA  1 
ATOM   7872  C  C   . PHE C 1 299 ? 296.042 239.341 248.378 1.00 20.37  ? 299 PHE C C   1 
ATOM   7873  O  O   . PHE C 1 299 ? 296.275 238.843 247.273 1.00 24.68  ? 299 PHE C O   1 
ATOM   7874  C  CB  . PHE C 1 299 ? 293.774 240.344 248.788 1.00 15.85  ? 299 PHE C CB  1 
ATOM   7875  C  CG  . PHE C 1 299 ? 293.713 240.774 247.343 1.00 17.88  ? 299 PHE C CG  1 
ATOM   7876  C  CD1 . PHE C 1 299 ? 294.652 241.650 246.822 1.00 17.24  ? 299 PHE C CD1 1 
ATOM   7877  C  CD2 . PHE C 1 299 ? 292.712 240.307 246.509 1.00 18.04  ? 299 PHE C CD2 1 
ATOM   7878  C  CE1 . PHE C 1 299 ? 294.597 242.042 245.502 1.00 18.06  ? 299 PHE C CE1 1 
ATOM   7879  C  CE2 . PHE C 1 299 ? 292.651 240.700 245.186 1.00 14.10  ? 299 PHE C CE2 1 
ATOM   7880  C  CZ  . PHE C 1 299 ? 293.596 241.568 244.683 1.00 17.04  ? 299 PHE C CZ  1 
ATOM   7881  N  N   . CYS C 1 300 ? 296.944 240.079 249.027 1.00 20.81  ? 300 CYS C N   1 
ATOM   7882  C  CA  . CYS C 1 300 ? 298.274 240.276 248.458 1.00 20.34  ? 300 CYS C CA  1 
ATOM   7883  C  C   . CYS C 1 300 ? 299.031 238.957 248.356 1.00 21.59  ? 300 CYS C C   1 
ATOM   7884  O  O   . CYS C 1 300 ? 299.713 238.697 247.357 1.00 23.77  ? 300 CYS C O   1 
ATOM   7885  C  CB  . CYS C 1 300 ? 299.062 241.286 249.291 1.00 17.73  ? 300 CYS C CB  1 
ATOM   7886  S  SG  . CYS C 1 300 ? 298.516 242.997 249.109 1.00 26.95  ? 300 CYS C SG  1 
ATOM   7887  N  N   . ALA C 1 301 ? 298.929 238.112 249.385 1.00 24.30  ? 301 ALA C N   1 
ATOM   7888  C  CA  . ALA C 1 301 ? 299.578 236.805 249.329 1.00 19.10  ? 301 ALA C CA  1 
ATOM   7889  C  C   . ALA C 1 301 ? 299.002 235.948 248.206 1.00 19.47  ? 301 ALA C C   1 
ATOM   7890  O  O   . ALA C 1 301 ? 299.747 235.285 247.469 1.00 25.59  ? 301 ALA C O   1 
ATOM   7891  C  CB  . ALA C 1 301 ? 299.443 236.092 250.674 1.00 18.57  ? 301 ALA C CB  1 
ATOM   7892  N  N   . TRP C 1 302 ? 297.675 235.950 248.060 1.00 19.52  ? 302 TRP C N   1 
ATOM   7893  C  CA  . TRP C 1 302 ? 297.058 235.206 246.969 1.00 18.88  ? 302 TRP C CA  1 
ATOM   7894  C  C   . TRP C 1 302 ? 297.518 235.732 245.618 1.00 22.11  ? 302 TRP C C   1 
ATOM   7895  O  O   . TRP C 1 302 ? 297.759 234.955 244.692 1.00 25.83  ? 302 TRP C O   1 
ATOM   7896  C  CB  . TRP C 1 302 ? 295.536 235.274 247.059 1.00 17.66  ? 302 TRP C CB  1 
ATOM   7897  C  CG  . TRP C 1 302 ? 294.885 234.887 245.766 1.00 18.37  ? 302 TRP C CG  1 
ATOM   7898  C  CD1 . TRP C 1 302 ? 294.643 233.624 245.318 1.00 17.17  ? 302 TRP C CD1 1 
ATOM   7899  C  CD2 . TRP C 1 302 ? 294.422 235.773 244.739 1.00 20.87  ? 302 TRP C CD2 1 
ATOM   7900  N  NE1 . TRP C 1 302 ? 294.050 233.666 244.082 1.00 19.09  ? 302 TRP C NE1 1 
ATOM   7901  C  CE2 . TRP C 1 302 ? 293.903 234.974 243.704 1.00 18.90  ? 302 TRP C CE2 1 
ATOM   7902  C  CE3 . TRP C 1 302 ? 294.395 237.163 244.597 1.00 20.14  ? 302 TRP C CE3 1 
ATOM   7903  C  CZ2 . TRP C 1 302 ? 293.359 235.518 242.545 1.00 23.38  ? 302 TRP C CZ2 1 
ATOM   7904  C  CZ3 . TRP C 1 302 ? 293.857 237.700 243.447 1.00 19.44  ? 302 TRP C CZ3 1 
ATOM   7905  C  CH2 . TRP C 1 302 ? 293.346 236.880 242.435 1.00 25.76  ? 302 TRP C CH2 1 
ATOM   7906  N  N   . ARG C 1 303 ? 297.617 237.055 245.481 1.00 24.41  ? 303 ARG C N   1 
ATOM   7907  C  CA  . ARG C 1 303 ? 298.068 237.642 244.226 1.00 20.18  ? 303 ARG C CA  1 
ATOM   7908  C  C   . ARG C 1 303 ? 299.499 237.232 243.911 1.00 25.11  ? 303 ARG C C   1 
ATOM   7909  O  O   . ARG C 1 303 ? 299.825 236.929 242.759 1.00 31.25  ? 303 ARG C O   1 
ATOM   7910  C  CB  . ARG C 1 303 ? 297.939 239.163 244.292 1.00 20.71  ? 303 ARG C CB  1 
ATOM   7911  C  CG  . ARG C 1 303 ? 297.929 239.858 242.946 1.00 22.29  ? 303 ARG C CG  1 
ATOM   7912  C  CD  . ARG C 1 303 ? 297.934 241.364 243.125 1.00 27.06  ? 303 ARG C CD  1 
ATOM   7913  N  NE  . ARG C 1 303 ? 298.322 242.069 241.911 1.00 27.18  ? 303 ARG C NE  1 
ATOM   7914  C  CZ  . ARG C 1 303 ? 298.111 243.360 241.699 1.00 26.08  ? 303 ARG C CZ  1 
ATOM   7915  N  NH1 . ARG C 1 303 ? 297.508 244.117 242.598 1.00 24.36  ? 303 ARG C NH1 1 
ATOM   7916  N  NH2 . ARG C 1 303 ? 298.514 243.904 240.555 1.00 30.10  ? 303 ARG C NH2 1 
ATOM   7917  N  N   . SER C 1 304 ? 300.368 237.215 244.923 1.00 24.93  ? 304 SER C N   1 
ATOM   7918  C  CA  . SER C 1 304 ? 301.742 236.771 244.703 1.00 26.76  ? 304 SER C CA  1 
ATOM   7919  C  C   . SER C 1 304 ? 301.781 235.322 244.233 1.00 33.51  ? 304 SER C C   1 
ATOM   7920  O  O   . SER C 1 304 ? 302.479 234.987 243.268 1.00 37.52  ? 304 SER C O   1 
ATOM   7921  C  CB  . SER C 1 304 ? 302.562 236.943 245.981 1.00 25.85  ? 304 SER C CB  1 
ATOM   7922  O  OG  . SER C 1 304 ? 302.345 238.215 246.560 1.00 31.46  ? 304 SER C OG  1 
ATOM   7923  N  N   . GLU C 1 305 ? 301.033 234.445 244.906 1.00 36.42  ? 305 GLU C N   1 
ATOM   7924  C  CA  . GLU C 1 305 ? 301.018 233.040 244.504 1.00 39.58  ? 305 GLU C CA  1 
ATOM   7925  C  C   . GLU C 1 305 ? 300.466 232.876 243.091 1.00 42.72  ? 305 GLU C C   1 
ATOM   7926  O  O   . GLU C 1 305 ? 301.012 232.116 242.280 1.00 46.76  ? 305 GLU C O   1 
ATOM   7927  C  CB  . GLU C 1 305 ? 300.200 232.223 245.502 1.00 39.40  ? 305 GLU C CB  1 
ATOM   7928  C  CG  . GLU C 1 305 ? 300.573 230.755 245.565 1.00 54.67  ? 305 GLU C CG  1 
ATOM   7929  C  CD  . GLU C 1 305 ? 299.507 229.913 246.239 1.00 69.02  ? 305 GLU C CD  1 
ATOM   7930  O  OE1 . GLU C 1 305 ? 298.308 230.159 245.989 1.00 65.90  ? 305 GLU C OE1 1 
ATOM   7931  O  OE2 . GLU C 1 305 ? 299.866 229.005 247.018 1.00 66.05  ? 305 GLU C OE2 1 
ATOM   7932  N  N   . PHE C 1 306 ? 299.381 233.588 242.784 1.00 40.09  ? 306 PHE C N   1 
ATOM   7933  C  CA  . PHE C 1 306 ? 298.759 233.514 241.468 1.00 40.78  ? 306 PHE C CA  1 
ATOM   7934  C  C   . PHE C 1 306 ? 299.716 233.983 240.382 1.00 44.96  ? 306 PHE C C   1 
ATOM   7935  O  O   . PHE C 1 306 ? 299.806 233.369 239.313 1.00 49.93  ? 306 PHE C O   1 
ATOM   7936  C  CB  . PHE C 1 306 ? 297.483 234.358 241.479 1.00 37.45  ? 306 PHE C CB  1 
ATOM   7937  C  CG  . PHE C 1 306 ? 296.470 233.961 240.451 1.00 43.96  ? 306 PHE C CG  1 
ATOM   7938  C  CD1 . PHE C 1 306 ? 295.578 232.935 240.704 1.00 49.26  ? 306 PHE C CD1 1 
ATOM   7939  C  CD2 . PHE C 1 306 ? 296.375 234.645 239.254 1.00 50.06  ? 306 PHE C CD2 1 
ATOM   7940  C  CE1 . PHE C 1 306 ? 294.632 232.577 239.769 1.00 49.44  ? 306 PHE C CE1 1 
ATOM   7941  C  CE2 . PHE C 1 306 ? 295.428 234.294 238.316 1.00 52.20  ? 306 PHE C CE2 1 
ATOM   7942  C  CZ  . PHE C 1 306 ? 294.557 233.257 238.573 1.00 53.85  ? 306 PHE C CZ  1 
ATOM   7943  N  N   . PHE C 1 307 ? 300.436 235.075 240.639 1.00 45.07  ? 307 PHE C N   1 
ATOM   7944  C  CA  . PHE C 1 307 ? 301.407 235.576 239.675 1.00 45.49  ? 307 PHE C CA  1 
ATOM   7945  C  C   . PHE C 1 307 ? 302.541 234.582 239.472 1.00 50.01  ? 307 PHE C C   1 
ATOM   7946  O  O   . PHE C 1 307 ? 302.954 234.325 238.336 1.00 58.60  ? 307 PHE C O   1 
ATOM   7947  C  CB  . PHE C 1 307 ? 301.941 236.931 240.146 1.00 42.92  ? 307 PHE C CB  1 
ATOM   7948  C  CG  . PHE C 1 307 ? 302.800 237.642 239.136 1.00 50.60  ? 307 PHE C CG  1 
ATOM   7949  C  CD1 . PHE C 1 307 ? 304.069 237.183 238.831 1.00 58.61  ? 307 PHE C CD1 1 
ATOM   7950  C  CD2 . PHE C 1 307 ? 302.333 238.777 238.497 1.00 56.22  ? 307 PHE C CD2 1 
ATOM   7951  C  CE1 . PHE C 1 307 ? 304.854 237.839 237.907 1.00 62.41  ? 307 PHE C CE1 1 
ATOM   7952  C  CE2 . PHE C 1 307 ? 303.115 239.437 237.573 1.00 59.90  ? 307 PHE C CE2 1 
ATOM   7953  C  CZ  . PHE C 1 307 ? 304.376 238.967 237.278 1.00 62.89  ? 307 PHE C CZ  1 
ATOM   7954  N  N   . ARG C 1 308 ? 303.056 234.006 240.561 1.00 51.79  ? 308 ARG C N   1 
ATOM   7955  C  CA  . ARG C 1 308 ? 304.163 233.064 240.431 1.00 51.78  ? 308 ARG C CA  1 
ATOM   7956  C  C   . ARG C 1 308 ? 303.748 231.827 239.644 1.00 54.97  ? 308 ARG C C   1 
ATOM   7957  O  O   . ARG C 1 308 ? 304.525 231.313 238.831 1.00 59.76  ? 308 ARG C O   1 
ATOM   7958  C  CB  . ARG C 1 308 ? 304.692 232.667 241.808 1.00 49.14  ? 308 ARG C CB  1 
ATOM   7959  C  CG  . ARG C 1 308 ? 305.895 233.476 242.259 1.00 48.78  ? 308 ARG C CG  1 
ATOM   7960  C  CD  . ARG C 1 308 ? 305.933 233.611 243.769 1.00 49.56  ? 308 ARG C CD  1 
ATOM   7961  N  NE  . ARG C 1 308 ? 305.190 232.543 244.426 1.00 56.47  ? 308 ARG C NE  1 
ATOM   7962  C  CZ  . ARG C 1 308 ? 304.623 232.649 245.620 1.00 59.40  ? 308 ARG C CZ  1 
ATOM   7963  N  NH1 . ARG C 1 308 ? 304.690 233.768 246.320 1.00 51.56  ? 308 ARG C NH1 1 
ATOM   7964  N  NH2 . ARG C 1 308 ? 303.972 231.604 246.123 1.00 56.28  ? 308 ARG C NH2 1 
ATOM   7965  N  N   . LYS C 1 309 ? 302.529 231.332 239.871 1.00 56.55  ? 309 LYS C N   1 
ATOM   7966  C  CA  . LYS C 1 309 ? 302.099 230.116 239.186 1.00 60.18  ? 309 LYS C CA  1 
ATOM   7967  C  C   . LYS C 1 309 ? 302.133 230.267 237.669 1.00 62.62  ? 309 LYS C C   1 
ATOM   7968  O  O   . LYS C 1 309 ? 302.365 229.284 236.956 1.00 67.47  ? 309 LYS C O   1 
ATOM   7969  C  CB  . LYS C 1 309 ? 300.694 229.719 239.641 1.00 54.88  ? 309 LYS C CB  1 
ATOM   7970  C  CG  . LYS C 1 309 ? 300.571 229.463 241.130 1.00 58.13  ? 309 LYS C CG  1 
ATOM   7971  C  CD  . LYS C 1 309 ? 301.587 228.432 241.593 1.00 68.78  ? 309 LYS C CD  1 
ATOM   7972  C  CE  . LYS C 1 309 ? 301.653 228.356 243.111 1.00 67.22  ? 309 LYS C CE  1 
ATOM   7973  N  NZ  . LYS C 1 309 ? 302.643 229.312 243.678 1.00 61.05  ? 309 LYS C NZ  1 
ATOM   7974  N  N   . GLY C 1 310 ? 301.910 231.474 237.157 1.00 66.28  ? 310 GLY C N   1 
ATOM   7975  C  CA  . GLY C 1 310 ? 301.758 231.658 235.726 1.00 72.24  ? 310 GLY C CA  1 
ATOM   7976  C  C   . GLY C 1 310 ? 302.947 232.246 234.993 1.00 78.25  ? 310 GLY C C   1 
ATOM   7977  O  O   . GLY C 1 310 ? 302.781 232.808 233.906 1.00 76.15  ? 310 GLY C O   1 
ATOM   7978  N  N   . ILE C 1 311 ? 304.147 232.131 235.558 1.00 78.86  ? 311 ILE C N   1 
ATOM   7979  C  CA  . ILE C 1 311 ? 305.343 232.691 234.942 1.00 85.48  ? 311 ILE C CA  1 
ATOM   7980  C  C   . ILE C 1 311 ? 306.454 231.649 234.947 1.00 90.99  ? 311 ILE C C   1 
ATOM   7981  O  O   . ILE C 1 311 ? 306.481 230.743 235.786 1.00 86.66  ? 311 ILE C O   1 
ATOM   7982  C  CB  . ILE C 1 311 ? 305.800 233.983 235.655 1.00 82.45  ? 311 ILE C CB  1 
ATOM   7983  C  CG1 . ILE C 1 311 ? 304.719 235.058 235.543 1.00 78.01  ? 311 ILE C CG1 1 
ATOM   7984  C  CG2 . ILE C 1 311 ? 307.103 234.495 235.066 1.00 85.20  ? 311 ILE C CG2 1 
ATOM   7985  C  CD1 . ILE C 1 311 ? 304.709 235.772 234.208 1.00 77.06  ? 311 ILE C CD1 1 
ATOM   7986  N  N   . ARG C 1 312 ? 307.375 231.785 233.995 1.00 96.16  ? 312 ARG C N   1 
ATOM   7987  C  CA  . ARG C 1 312 ? 308.529 230.902 233.871 1.00 102.11 ? 312 ARG C CA  1 
ATOM   7988  C  C   . ARG C 1 312 ? 309.775 231.653 234.323 1.00 103.87 ? 312 ARG C C   1 
ATOM   7989  O  O   . ARG C 1 312 ? 310.119 232.694 233.752 1.00 101.78 ? 312 ARG C O   1 
ATOM   7990  C  CB  . ARG C 1 312 ? 308.687 230.414 232.431 1.00 101.79 ? 312 ARG C CB  1 
ATOM   7991  C  CG  . ARG C 1 312 ? 307.526 229.576 231.927 1.00 103.22 ? 312 ARG C CG  1 
ATOM   7992  C  CD  . ARG C 1 312 ? 307.619 228.143 232.424 1.00 107.54 ? 312 ARG C CD  1 
ATOM   7993  N  NE  . ARG C 1 312 ? 308.801 227.462 231.907 1.00 114.41 ? 312 ARG C NE  1 
ATOM   7994  C  CZ  . ARG C 1 312 ? 309.834 227.085 232.647 1.00 113.75 ? 312 ARG C CZ  1 
ATOM   7995  N  NH1 . ARG C 1 312 ? 309.868 227.305 233.951 1.00 111.67 ? 312 ARG C NH1 1 
ATOM   7996  N  NH2 . ARG C 1 312 ? 310.859 226.469 232.064 1.00 109.90 ? 312 ARG C NH2 1 
ATOM   7997  N  N   . LEU C 1 313 ? 310.451 231.122 235.341 1.00 105.93 ? 313 LEU C N   1 
ATOM   7998  C  CA  . LEU C 1 313 ? 311.611 231.779 235.926 1.00 107.50 ? 313 LEU C CA  1 
ATOM   7999  C  C   . LEU C 1 313 ? 312.854 230.926 235.729 1.00 107.96 ? 313 LEU C C   1 
ATOM   8000  O  O   . LEU C 1 313 ? 312.867 229.757 236.144 1.00 107.02 ? 313 LEU C O   1 
ATOM   8001  C  CB  . LEU C 1 313 ? 311.385 232.047 237.412 1.00 104.92 ? 313 LEU C CB  1 
ATOM   8002  C  CG  . LEU C 1 313 ? 310.552 233.278 237.769 1.00 98.83  ? 313 LEU C CG  1 
ATOM   8003  C  CD1 . LEU C 1 313 ? 310.873 233.736 239.181 1.00 92.75  ? 313 LEU C CD1 1 
ATOM   8004  C  CD2 . LEU C 1 313 ? 310.785 234.400 236.768 1.00 96.11  ? 313 LEU C CD2 1 
ATOM   8005  N  N   . PRO C 1 314 ? 313.905 231.454 235.106 1.00 111.74 ? 314 PRO C N   1 
ATOM   8006  C  CA  . PRO C 1 314 ? 315.161 230.704 235.012 1.00 112.57 ? 314 PRO C CA  1 
ATOM   8007  C  C   . PRO C 1 314 ? 315.673 230.304 236.388 1.00 114.90 ? 314 PRO C C   1 
ATOM   8008  O  O   . PRO C 1 314 ? 315.238 230.818 237.421 1.00 112.84 ? 314 PRO C O   1 
ATOM   8009  C  CB  . PRO C 1 314 ? 316.114 231.691 234.331 1.00 110.23 ? 314 PRO C CB  1 
ATOM   8010  C  CG  . PRO C 1 314 ? 315.222 232.587 233.545 1.00 110.64 ? 314 PRO C CG  1 
ATOM   8011  C  CD  . PRO C 1 314 ? 313.940 232.702 234.324 1.00 110.12 ? 314 PRO C CD  1 
ATOM   8012  N  N   . GLU C 1 315 ? 316.614 229.361 236.390 1.00 117.59 ? 315 GLU C N   1 
ATOM   8013  C  CA  . GLU C 1 315 ? 317.212 228.910 237.640 1.00 119.07 ? 315 GLU C CA  1 
ATOM   8014  C  C   . GLU C 1 315 ? 317.861 230.079 238.370 1.00 119.21 ? 315 GLU C C   1 
ATOM   8015  O  O   . GLU C 1 315 ? 318.620 230.853 237.779 1.00 115.78 ? 315 GLU C O   1 
ATOM   8016  C  CB  . GLU C 1 315 ? 318.246 227.818 237.364 1.00 119.15 ? 315 GLU C CB  1 
ATOM   8017  C  CG  . GLU C 1 315 ? 319.010 227.349 238.595 1.00 119.59 ? 315 GLU C CG  1 
ATOM   8018  C  CD  . GLU C 1 315 ? 318.102 226.806 239.682 1.00 122.51 ? 315 GLU C CD  1 
ATOM   8019  O  OE1 . GLU C 1 315 ? 317.621 227.603 240.515 1.00 122.79 ? 315 GLU C OE1 1 
ATOM   8020  O  OE2 . GLU C 1 315 ? 317.872 225.578 239.707 1.00 121.55 ? 315 GLU C OE2 1 
ATOM   8021  N  N   . GLY C 1 316 ? 317.558 230.203 239.661 1.00 117.66 ? 316 GLY C N   1 
ATOM   8022  C  CA  . GLY C 1 316 ? 318.145 231.216 240.504 1.00 111.20 ? 316 GLY C CA  1 
ATOM   8023  C  C   . GLY C 1 316 ? 317.360 232.507 240.608 1.00 107.79 ? 316 GLY C C   1 
ATOM   8024  O  O   . GLY C 1 316 ? 317.578 233.271 241.554 1.00 106.82 ? 316 GLY C O   1 
ATOM   8025  N  N   . GLN C 1 317 ? 316.449 232.770 239.674 1.00 106.54 ? 317 GLN C N   1 
ATOM   8026  C  CA  . GLN C 1 317 ? 315.702 234.020 239.698 1.00 102.79 ? 317 GLN C CA  1 
ATOM   8027  C  C   . GLN C 1 317 ? 314.851 234.112 240.958 1.00 100.38 ? 317 GLN C C   1 
ATOM   8028  O  O   . GLN C 1 317 ? 314.197 233.146 241.360 1.00 98.51  ? 317 GLN C O   1 
ATOM   8029  C  CB  . GLN C 1 317 ? 314.819 234.139 238.456 1.00 102.84 ? 317 GLN C CB  1 
ATOM   8030  C  CG  . GLN C 1 317 ? 314.046 235.447 238.377 1.00 98.96  ? 317 GLN C CG  1 
ATOM   8031  C  CD  . GLN C 1 317 ? 314.163 236.119 237.023 1.00 99.46  ? 317 GLN C CD  1 
ATOM   8032  O  OE1 . GLN C 1 317 ? 314.679 235.537 236.070 1.00 100.99 ? 317 GLN C OE1 1 
ATOM   8033  N  NE2 . GLN C 1 317 ? 313.685 237.354 236.935 1.00 96.34  ? 317 GLN C NE2 1 
ATOM   8034  N  N   . ILE C 1 318 ? 314.864 235.288 241.582 1.00 99.40  ? 318 ILE C N   1 
ATOM   8035  C  CA  . ILE C 1 318 ? 314.114 235.545 242.805 1.00 94.70  ? 318 ILE C CA  1 
ATOM   8036  C  C   . ILE C 1 318 ? 313.337 236.840 242.631 1.00 86.14  ? 318 ILE C C   1 
ATOM   8037  O  O   . ILE C 1 318 ? 313.920 237.881 242.306 1.00 85.71  ? 318 ILE C O   1 
ATOM   8038  C  CB  . ILE C 1 318 ? 315.036 235.630 244.036 1.00 95.93  ? 318 ILE C CB  1 
ATOM   8039  C  CG1 . ILE C 1 318 ? 315.960 234.413 244.089 1.00 100.59 ? 318 ILE C CG1 1 
ATOM   8040  C  CG2 . ILE C 1 318 ? 314.214 235.735 245.309 1.00 87.66  ? 318 ILE C CG2 1 
ATOM   8041  C  CD1 . ILE C 1 318 ? 315.225 233.098 244.211 1.00 99.26  ? 318 ILE C CD1 1 
ATOM   8042  N  N   . MET C 1 319 ? 312.028 236.778 242.848 1.00 82.31  ? 319 MET C N   1 
ATOM   8043  C  CA  . MET C 1 319 ? 311.160 237.942 242.772 1.00 77.16  ? 319 MET C CA  1 
ATOM   8044  C  C   . MET C 1 319 ? 310.611 238.280 244.151 1.00 68.19  ? 319 MET C C   1 
ATOM   8045  O  O   . MET C 1 319 ? 310.658 237.471 245.081 1.00 62.00  ? 319 MET C O   1 
ATOM   8046  C  CB  . MET C 1 319 ? 309.999 237.710 241.799 1.00 68.40  ? 319 MET C CB  1 
ATOM   8047  C  CG  . MET C 1 319 ? 310.320 236.782 240.646 1.00 77.79  ? 319 MET C CG  1 
ATOM   8048  S  SD  . MET C 1 319 ? 308.825 236.203 239.822 1.00 101.34 ? 319 MET C SD  1 
ATOM   8049  C  CE  . MET C 1 319 ? 307.803 237.670 239.917 1.00 77.24  ? 319 MET C CE  1 
ATOM   8050  N  N   . ASP C 1 320 ? 310.091 239.495 244.270 1.00 61.39  ? 320 ASP C N   1 
ATOM   8051  C  CA  . ASP C 1 320 ? 309.434 239.948 245.484 1.00 49.46  ? 320 ASP C CA  1 
ATOM   8052  C  C   . ASP C 1 320 ? 307.921 239.842 245.330 1.00 49.09  ? 320 ASP C C   1 
ATOM   8053  O  O   . ASP C 1 320 ? 307.382 239.844 244.222 1.00 51.84  ? 320 ASP C O   1 
ATOM   8054  C  CB  . ASP C 1 320 ? 309.837 241.385 245.821 1.00 44.66  ? 320 ASP C CB  1 
ATOM   8055  C  CG  . ASP C 1 320 ? 309.923 241.628 247.314 1.00 50.77  ? 320 ASP C CG  1 
ATOM   8056  O  OD1 . ASP C 1 320 ? 309.846 240.644 248.077 1.00 51.81  ? 320 ASP C OD1 1 
ATOM   8057  O  OD2 . ASP C 1 320 ? 310.067 242.797 247.727 1.00 49.72  ? 320 ASP C OD2 1 
ATOM   8058  N  N   . ASP C 1 321 ? 307.242 239.746 246.465 1.00 44.81  ? 321 ASP C N   1 
ATOM   8059  C  CA  . ASP C 1 321 ? 305.808 239.514 246.491 1.00 35.60  ? 321 ASP C CA  1 
ATOM   8060  C  C   . ASP C 1 321 ? 305.038 240.830 246.490 1.00 30.48  ? 321 ASP C C   1 
ATOM   8061  O  O   . ASP C 1 321 ? 305.553 241.883 246.874 1.00 35.13  ? 321 ASP C O   1 
ATOM   8062  C  CB  . ASP C 1 321 ? 305.426 238.692 247.723 1.00 37.93  ? 321 ASP C CB  1 
ATOM   8063  C  CG  . ASP C 1 321 ? 305.735 237.217 247.560 1.00 49.98  ? 321 ASP C CG  1 
ATOM   8064  O  OD1 . ASP C 1 321 ? 305.865 236.759 246.407 1.00 50.96  ? 321 ASP C OD1 1 
ATOM   8065  O  OD2 . ASP C 1 321 ? 305.846 236.515 248.587 1.00 55.50  ? 321 ASP C OD2 1 
ATOM   8066  N  N   . PHE C 1 322 ? 303.786 240.755 246.044 1.00 26.87  ? 322 PHE C N   1 
ATOM   8067  C  CA  . PHE C 1 322 ? 302.867 241.870 246.211 1.00 21.18  ? 322 PHE C CA  1 
ATOM   8068  C  C   . PHE C 1 322 ? 302.637 242.135 247.693 1.00 23.30  ? 322 PHE C C   1 
ATOM   8069  O  O   . PHE C 1 322 ? 302.602 241.215 248.514 1.00 26.66  ? 322 PHE C O   1 
ATOM   8070  C  CB  . PHE C 1 322 ? 301.535 241.578 245.519 1.00 23.15  ? 322 PHE C CB  1 
ATOM   8071  C  CG  . PHE C 1 322 ? 301.611 241.589 244.021 1.00 22.34  ? 322 PHE C CG  1 
ATOM   8072  C  CD1 . PHE C 1 322 ? 301.608 242.784 243.326 1.00 22.83  ? 322 PHE C CD1 1 
ATOM   8073  C  CD2 . PHE C 1 322 ? 301.686 240.406 243.308 1.00 23.76  ? 322 PHE C CD2 1 
ATOM   8074  C  CE1 . PHE C 1 322 ? 301.676 242.800 241.950 1.00 24.61  ? 322 PHE C CE1 1 
ATOM   8075  C  CE2 . PHE C 1 322 ? 301.756 240.416 241.932 1.00 22.73  ? 322 PHE C CE2 1 
ATOM   8076  C  CZ  . PHE C 1 322 ? 301.751 241.614 241.251 1.00 24.44  ? 322 PHE C CZ  1 
ATOM   8077  N  N   . ARG C 1 323 ? 302.485 243.409 248.036 1.00 20.51  ? 323 ARG C N   1 
ATOM   8078  C  CA  . ARG C 1 323 ? 302.333 243.790 249.432 1.00 17.67  ? 323 ARG C CA  1 
ATOM   8079  C  C   . ARG C 1 323 ? 301.604 245.120 249.504 1.00 18.71  ? 323 ARG C C   1 
ATOM   8080  O  O   . ARG C 1 323 ? 301.483 245.837 248.509 1.00 20.47  ? 323 ARG C O   1 
ATOM   8081  C  CB  . ARG C 1 323 ? 303.690 243.893 250.132 1.00 16.33  ? 323 ARG C CB  1 
ATOM   8082  C  CG  . ARG C 1 323 ? 304.722 244.635 249.309 1.00 19.02  ? 323 ARG C CG  1 
ATOM   8083  C  CD  . ARG C 1 323 ? 305.948 244.997 250.117 1.00 19.61  ? 323 ARG C CD  1 
ATOM   8084  N  NE  . ARG C 1 323 ? 306.934 245.672 249.283 1.00 23.48  ? 323 ARG C NE  1 
ATOM   8085  C  CZ  . ARG C 1 323 ? 307.219 246.965 249.357 1.00 21.50  ? 323 ARG C CZ  1 
ATOM   8086  N  NH1 . ARG C 1 323 ? 306.615 247.757 250.226 1.00 22.91  ? 323 ARG C NH1 1 
ATOM   8087  N  NH2 . ARG C 1 323 ? 308.127 247.476 248.533 1.00 21.06  ? 323 ARG C NH2 1 
ATOM   8088  N  N   . LEU C 1 324 ? 301.107 245.432 250.695 1.00 20.04  ? 324 LEU C N   1 
ATOM   8089  C  CA  . LEU C 1 324 ? 300.632 246.777 250.954 1.00 16.16  ? 324 LEU C CA  1 
ATOM   8090  C  C   . LEU C 1 324 ? 301.819 247.735 251.009 1.00 19.16  ? 324 LEU C C   1 
ATOM   8091  O  O   . LEU C 1 324 ? 302.903 247.368 251.469 1.00 24.40  ? 324 LEU C O   1 
ATOM   8092  C  CB  . LEU C 1 324 ? 299.857 246.839 252.267 1.00 15.16  ? 324 LEU C CB  1 
ATOM   8093  C  CG  . LEU C 1 324 ? 298.523 246.098 252.340 1.00 17.19  ? 324 LEU C CG  1 
ATOM   8094  C  CD1 . LEU C 1 324 ? 298.019 246.063 253.773 1.00 13.93  ? 324 LEU C CD1 1 
ATOM   8095  C  CD2 . LEU C 1 324 ? 297.500 246.744 251.421 1.00 17.71  ? 324 LEU C CD2 1 
ATOM   8096  N  N   . PRO C 1 325 ? 301.645 248.965 250.538 1.00 20.02  ? 325 PRO C N   1 
ATOM   8097  C  CA  . PRO C 1 325 ? 302.734 249.940 250.621 1.00 17.56  ? 325 PRO C CA  1 
ATOM   8098  C  C   . PRO C 1 325 ? 302.998 250.353 252.057 1.00 19.20  ? 325 PRO C C   1 
ATOM   8099  O  O   . PRO C 1 325 ? 302.119 250.296 252.920 1.00 23.85  ? 325 PRO C O   1 
ATOM   8100  C  CB  . PRO C 1 325 ? 302.215 251.121 249.795 1.00 17.49  ? 325 PRO C CB  1 
ATOM   8101  C  CG  . PRO C 1 325 ? 300.733 250.999 249.876 1.00 13.88  ? 325 PRO C CG  1 
ATOM   8102  C  CD  . PRO C 1 325 ? 300.449 249.525 249.889 1.00 14.98  ? 325 PRO C CD  1 
ATOM   8103  N  N   . THR C 1 326 ? 304.234 250.768 252.312 1.00 20.14  ? 326 THR C N   1 
ATOM   8104  C  CA  . THR C 1 326 ? 304.514 251.469 253.552 1.00 19.29  ? 326 THR C CA  1 
ATOM   8105  C  C   . THR C 1 326 ? 303.937 252.879 253.474 1.00 17.47  ? 326 THR C C   1 
ATOM   8106  O  O   . THR C 1 326 ? 303.709 253.423 252.392 1.00 22.84  ? 326 THR C O   1 
ATOM   8107  C  CB  . THR C 1 326 ? 306.019 251.522 253.822 1.00 21.65  ? 326 THR C CB  1 
ATOM   8108  O  OG1 . THR C 1 326 ? 306.644 252.411 252.891 1.00 25.85  ? 326 THR C OG1 1 
ATOM   8109  C  CG2 . THR C 1 326 ? 306.638 250.143 253.681 1.00 19.12  ? 326 THR C CG2 1 
ATOM   8110  N  N   . GLU C 1 327 ? 303.684 253.472 254.640 1.00 17.35  ? 327 GLU C N   1 
ATOM   8111  C  CA  . GLU C 1 327 ? 303.122 254.817 254.643 1.00 19.03  ? 327 GLU C CA  1 
ATOM   8112  C  C   . GLU C 1 327 ? 304.090 255.814 254.017 1.00 19.92  ? 327 GLU C C   1 
ATOM   8113  O  O   . GLU C 1 327 ? 303.667 256.755 253.337 1.00 23.63  ? 327 GLU C O   1 
ATOM   8114  C  CB  . GLU C 1 327 ? 302.738 255.232 256.064 1.00 19.10  ? 327 GLU C CB  1 
ATOM   8115  C  CG  . GLU C 1 327 ? 303.898 255.606 256.963 1.00 21.23  ? 327 GLU C CG  1 
ATOM   8116  C  CD  . GLU C 1 327 ? 303.449 256.400 258.171 1.00 27.46  ? 327 GLU C CD  1 
ATOM   8117  O  OE1 . GLU C 1 327 ? 302.588 257.288 258.008 1.00 29.67  ? 327 GLU C OE1 1 
ATOM   8118  O  OE2 . GLU C 1 327 ? 303.954 256.141 259.282 1.00 33.85  ? 327 GLU C OE2 1 
ATOM   8119  N  N   . ALA C 1 328 ? 305.395 255.612 254.217 1.00 16.63  ? 328 ALA C N   1 
ATOM   8120  C  CA  . ALA C 1 328 ? 306.383 256.463 253.560 1.00 15.50  ? 328 ALA C CA  1 
ATOM   8121  C  C   . ALA C 1 328 ? 306.362 256.275 252.048 1.00 17.36  ? 328 ALA C C   1 
ATOM   8122  O  O   . ALA C 1 328 ? 306.401 257.253 251.294 1.00 21.33  ? 328 ALA C O   1 
ATOM   8123  C  CB  . ALA C 1 328 ? 307.776 256.178 254.118 1.00 15.41  ? 328 ALA C CB  1 
ATOM   8124  N  N   . GLU C 1 329 ? 306.298 255.024 251.587 1.00 19.31  ? 329 GLU C N   1 
ATOM   8125  C  CA  . GLU C 1 329 ? 306.198 254.764 250.154 1.00 17.30  ? 329 GLU C CA  1 
ATOM   8126  C  C   . GLU C 1 329 ? 304.931 255.376 249.573 1.00 16.74  ? 329 GLU C C   1 
ATOM   8127  O  O   . GLU C 1 329 ? 304.961 256.001 248.505 1.00 19.12  ? 329 GLU C O   1 
ATOM   8128  C  CB  . GLU C 1 329 ? 306.220 253.259 249.895 1.00 18.84  ? 329 GLU C CB  1 
ATOM   8129  C  CG  . GLU C 1 329 ? 307.584 252.685 249.584 1.00 20.26  ? 329 GLU C CG  1 
ATOM   8130  C  CD  . GLU C 1 329 ? 307.579 251.169 249.586 1.00 26.72  ? 329 GLU C CD  1 
ATOM   8131  O  OE1 . GLU C 1 329 ? 306.598 250.579 250.081 1.00 29.13  ? 329 GLU C OE1 1 
ATOM   8132  O  OE2 . GLU C 1 329 ? 308.553 250.568 249.092 1.00 31.18  ? 329 GLU C OE2 1 
ATOM   8133  N  N   . TRP C 1 330 ? 303.804 255.201 250.265 1.00 15.34  ? 330 TRP C N   1 
ATOM   8134  C  CA  . TRP C 1 330 ? 302.546 255.751 249.781 1.00 14.56  ? 330 TRP C CA  1 
ATOM   8135  C  C   . TRP C 1 330 ? 302.604 257.269 249.704 1.00 17.95  ? 330 TRP C C   1 
ATOM   8136  O  O   . TRP C 1 330 ? 302.155 257.862 248.718 1.00 22.41  ? 330 TRP C O   1 
ATOM   8137  C  CB  . TRP C 1 330 ? 301.394 255.300 250.681 1.00 14.54  ? 330 TRP C CB  1 
ATOM   8138  C  CG  . TRP C 1 330 ? 300.047 255.660 250.139 1.00 16.80  ? 330 TRP C CG  1 
ATOM   8139  C  CD1 . TRP C 1 330 ? 299.201 254.848 249.448 1.00 15.74  ? 330 TRP C CD1 1 
ATOM   8140  C  CD2 . TRP C 1 330 ? 299.393 256.931 250.237 1.00 18.00  ? 330 TRP C CD2 1 
ATOM   8141  N  NE1 . TRP C 1 330 ? 298.061 255.532 249.109 1.00 19.78  ? 330 TRP C NE1 1 
ATOM   8142  C  CE2 . TRP C 1 330 ? 298.154 256.813 249.583 1.00 19.37  ? 330 TRP C CE2 1 
ATOM   8143  C  CE3 . TRP C 1 330 ? 299.736 258.157 250.816 1.00 16.73  ? 330 TRP C CE3 1 
ATOM   8144  C  CZ2 . TRP C 1 330 ? 297.258 257.872 249.490 1.00 16.68  ? 330 TRP C CZ2 1 
ATOM   8145  C  CZ3 . TRP C 1 330 ? 298.846 259.205 250.722 1.00 15.38  ? 330 TRP C CZ3 1 
ATOM   8146  C  CH2 . TRP C 1 330 ? 297.621 259.057 250.066 1.00 16.58  ? 330 TRP C CH2 1 
ATOM   8147  N  N   . GLU C 1 331 ? 303.142 257.919 250.737 1.00 20.68  ? 331 GLU C N   1 
ATOM   8148  C  CA  . GLU C 1 331 ? 303.218 259.375 250.722 1.00 18.71  ? 331 GLU C CA  1 
ATOM   8149  C  C   . GLU C 1 331 ? 304.151 259.864 249.622 1.00 19.81  ? 331 GLU C C   1 
ATOM   8150  O  O   . GLU C 1 331 ? 303.868 260.870 248.962 1.00 24.95  ? 331 GLU C O   1 
ATOM   8151  C  CB  . GLU C 1 331 ? 303.661 259.900 252.087 1.00 22.11  ? 331 GLU C CB  1 
ATOM   8152  C  CG  . GLU C 1 331 ? 303.660 261.416 252.187 1.00 27.18  ? 331 GLU C CG  1 
ATOM   8153  C  CD  . GLU C 1 331 ? 303.671 261.913 253.617 1.00 34.66  ? 331 GLU C CD  1 
ATOM   8154  O  OE1 . GLU C 1 331 ? 303.665 261.076 254.542 1.00 37.47  ? 331 GLU C OE1 1 
ATOM   8155  O  OE2 . GLU C 1 331 ? 303.676 263.145 253.818 1.00 34.83  ? 331 GLU C OE2 1 
ATOM   8156  N  N   . TYR C 1 332 ? 305.269 259.167 249.408 1.00 18.53  ? 332 TYR C N   1 
ATOM   8157  C  CA  . TYR C 1 332 ? 306.173 259.546 248.327 1.00 16.76  ? 332 TYR C CA  1 
ATOM   8158  C  C   . TYR C 1 332 ? 305.492 259.421 246.970 1.00 18.95  ? 332 TYR C C   1 
ATOM   8159  O  O   . TYR C 1 332 ? 305.666 260.282 246.099 1.00 19.48  ? 332 TYR C O   1 
ATOM   8160  C  CB  . TYR C 1 332 ? 307.437 258.689 248.373 1.00 16.42  ? 332 TYR C CB  1 
ATOM   8161  C  CG  . TYR C 1 332 ? 308.347 258.877 247.181 1.00 16.95  ? 332 TYR C CG  1 
ATOM   8162  C  CD1 . TYR C 1 332 ? 309.285 259.900 247.154 1.00 13.30  ? 332 TYR C CD1 1 
ATOM   8163  C  CD2 . TYR C 1 332 ? 308.268 258.035 246.083 1.00 15.42  ? 332 TYR C CD2 1 
ATOM   8164  C  CE1 . TYR C 1 332 ? 310.116 260.075 246.068 1.00 14.06  ? 332 TYR C CE1 1 
ATOM   8165  C  CE2 . TYR C 1 332 ? 309.095 258.204 244.993 1.00 14.43  ? 332 TYR C CE2 1 
ATOM   8166  C  CZ  . TYR C 1 332 ? 310.016 259.225 244.991 1.00 14.43  ? 332 TYR C CZ  1 
ATOM   8167  O  OH  . TYR C 1 332 ? 310.843 259.395 243.906 1.00 20.94  ? 332 TYR C OH  1 
ATOM   8168  N  N   . ALA C 1 333 ? 304.718 258.352 246.768 1.00 19.96  ? 333 ALA C N   1 
ATOM   8169  C  CA  . ALA C 1 333 ? 304.069 258.152 245.476 1.00 16.19  ? 333 ALA C CA  1 
ATOM   8170  C  C   . ALA C 1 333 ? 302.910 259.119 245.264 1.00 20.57  ? 333 ALA C C   1 
ATOM   8171  O  O   . ALA C 1 333 ? 302.665 259.550 244.133 1.00 23.01  ? 333 ALA C O   1 
ATOM   8172  C  CB  . ALA C 1 333 ? 303.586 256.708 245.349 1.00 14.37  ? 333 ALA C CB  1 
ATOM   8173  N  N   . ALA C 1 334 ? 302.188 259.469 246.330 1.00 20.75  ? 334 ALA C N   1 
ATOM   8174  C  CA  . ALA C 1 334 ? 301.041 260.360 246.192 1.00 18.63  ? 334 ALA C CA  1 
ATOM   8175  C  C   . ALA C 1 334 ? 301.469 261.764 245.788 1.00 20.35  ? 334 ALA C C   1 
ATOM   8176  O  O   . ALA C 1 334 ? 300.796 262.416 244.982 1.00 22.77  ? 334 ALA C O   1 
ATOM   8177  C  CB  . ALA C 1 334 ? 300.247 260.400 247.495 1.00 18.00  ? 334 ALA C CB  1 
ATOM   8178  N  N   . ARG C 1 335 ? 302.579 262.247 246.336 1.00 20.66  ? 335 ARG C N   1 
ATOM   8179  C  CA  . ARG C 1 335 ? 303.047 263.598 246.077 1.00 20.21  ? 335 ARG C CA  1 
ATOM   8180  C  C   . ARG C 1 335 ? 304.035 263.670 244.922 1.00 21.79  ? 335 ARG C C   1 
ATOM   8181  O  O   . ARG C 1 335 ? 304.685 264.703 244.743 1.00 24.64  ? 335 ARG C O   1 
ATOM   8182  C  CB  . ARG C 1 335 ? 303.668 264.187 247.344 1.00 20.02  ? 335 ARG C CB  1 
ATOM   8183  C  CG  . ARG C 1 335 ? 302.637 264.551 248.396 1.00 20.89  ? 335 ARG C CG  1 
ATOM   8184  C  CD  . ARG C 1 335 ? 303.230 264.564 249.787 1.00 24.10  ? 335 ARG C CD  1 
ATOM   8185  N  NE  . ARG C 1 335 ? 304.108 265.710 249.985 1.00 26.91  ? 335 ARG C NE  1 
ATOM   8186  C  CZ  . ARG C 1 335 ? 304.826 265.923 251.078 1.00 26.73  ? 335 ARG C CZ  1 
ATOM   8187  N  NH1 . ARG C 1 335 ? 304.789 265.088 252.102 1.00 27.16  ? 335 ARG C NH1 1 
ATOM   8188  N  NH2 . ARG C 1 335 ? 305.600 267.002 251.146 1.00 33.44  ? 335 ARG C NH2 1 
ATOM   8189  N  N   . MET C 1 336 ? 304.157 262.602 244.135 1.00 19.85  ? 336 MET C N   1 
ATOM   8190  C  CA  . MET C 1 336 ? 305.022 262.592 242.956 1.00 18.46  ? 336 MET C CA  1 
ATOM   8191  C  C   . MET C 1 336 ? 306.474 262.876 243.331 1.00 24.25  ? 336 MET C C   1 
ATOM   8192  O  O   . MET C 1 336 ? 307.213 263.518 242.583 1.00 29.58  ? 336 MET C O   1 
ATOM   8193  C  CB  . MET C 1 336 ? 304.529 263.590 241.907 1.00 22.57  ? 336 MET C CB  1 
ATOM   8194  C  CG  . MET C 1 336 ? 303.128 263.314 241.400 1.00 28.62  ? 336 MET C CG  1 
ATOM   8195  S  SD  . MET C 1 336 ? 301.939 264.556 241.943 1.00 43.64  ? 336 MET C SD  1 
ATOM   8196  C  CE  . MET C 1 336 ? 302.355 265.920 240.865 1.00 29.41  ? 336 MET C CE  1 
ATOM   8197  N  N   . GLY C 1 337 ? 306.885 262.398 244.503 1.00 21.23  ? 337 GLY C N   1 
ATOM   8198  C  CA  . GLY C 1 337 ? 308.256 262.578 244.937 1.00 16.93  ? 337 GLY C CA  1 
ATOM   8199  C  C   . GLY C 1 337 ? 308.695 264.018 245.049 1.00 22.94  ? 337 GLY C C   1 
ATOM   8200  O  O   . GLY C 1 337 ? 309.894 264.298 244.990 1.00 33.39  ? 337 GLY C O   1 
ATOM   8201  N  N   . ASP C 1 338 ? 307.755 264.944 245.215 1.00 25.49  ? 338 ASP C N   1 
ATOM   8202  C  CA  . ASP C 1 338 ? 308.046 266.367 245.311 1.00 26.99  ? 338 ASP C CA  1 
ATOM   8203  C  C   . ASP C 1 338 ? 307.530 266.887 246.643 1.00 30.66  ? 338 ASP C C   1 
ATOM   8204  O  O   . ASP C 1 338 ? 306.361 266.678 246.985 1.00 30.07  ? 338 ASP C O   1 
ATOM   8205  C  CB  . ASP C 1 338 ? 307.410 267.134 244.148 1.00 32.38  ? 338 ASP C CB  1 
ATOM   8206  C  CG  . ASP C 1 338 ? 307.955 268.540 244.007 1.00 41.27  ? 338 ASP C CG  1 
ATOM   8207  O  OD1 . ASP C 1 338 ? 307.794 269.340 244.952 1.00 41.97  ? 338 ASP C OD1 1 
ATOM   8208  O  OD2 . ASP C 1 338 ? 308.545 268.847 242.951 1.00 51.92  ? 338 ASP C OD2 1 
ATOM   8209  N  N   . SER C 1 339 ? 308.401 267.563 247.391 1.00 32.25  ? 339 SER C N   1 
ATOM   8210  C  CA  . SER C 1 339 ? 308.053 268.042 248.722 1.00 30.61  ? 339 SER C CA  1 
ATOM   8211  C  C   . SER C 1 339 ? 307.203 269.304 248.699 1.00 34.68  ? 339 SER C C   1 
ATOM   8212  O  O   . SER C 1 339 ? 306.685 269.699 249.749 1.00 36.66  ? 339 SER C O   1 
ATOM   8213  C  CB  . SER C 1 339 ? 309.323 268.299 249.535 1.00 30.02  ? 339 SER C CB  1 
ATOM   8214  O  OG  . SER C 1 339 ? 310.261 267.254 249.355 1.00 28.28  ? 339 SER C OG  1 
ATOM   8215  N  N   . ASN C 1 340 ? 307.047 269.943 247.544 1.00 33.38  ? 340 ASN C N   1 
ATOM   8216  C  CA  . ASN C 1 340 ? 306.255 271.159 247.425 1.00 32.37  ? 340 ASN C CA  1 
ATOM   8217  C  C   . ASN C 1 340 ? 304.774 270.885 247.208 1.00 34.99  ? 340 ASN C C   1 
ATOM   8218  O  O   . ASN C 1 340 ? 303.982 271.832 247.190 1.00 37.73  ? 340 ASN C O   1 
ATOM   8219  C  CB  . ASN C 1 340 ? 306.790 272.025 246.281 1.00 37.57  ? 340 ASN C CB  1 
ATOM   8220  C  CG  . ASN C 1 340 ? 308.080 272.734 246.641 1.00 42.34  ? 340 ASN C CG  1 
ATOM   8221  O  OD1 . ASN C 1 340 ? 308.236 273.237 247.752 1.00 46.76  ? 340 ASN C OD1 1 
ATOM   8222  N  ND2 . ASN C 1 340 ? 309.014 272.778 245.698 1.00 41.50  ? 340 ASN C ND2 1 
ATOM   8223  N  N   . ASN C 1 341 ? 304.381 269.625 247.049 1.00 34.67  ? 341 ASN C N   1 
ATOM   8224  C  CA  . ASN C 1 341 ? 303.000 269.259 246.771 1.00 26.18  ? 341 ASN C CA  1 
ATOM   8225  C  C   . ASN C 1 341 ? 302.313 268.813 248.054 1.00 28.84  ? 341 ASN C C   1 
ATOM   8226  O  O   . ASN C 1 341 ? 302.811 267.922 248.750 1.00 34.38  ? 341 ASN C O   1 
ATOM   8227  C  CB  . ASN C 1 341 ? 302.932 268.140 245.731 1.00 27.10  ? 341 ASN C CB  1 
ATOM   8228  C  CG  . ASN C 1 341 ? 303.595 268.515 244.424 1.00 31.53  ? 341 ASN C CG  1 
ATOM   8229  O  OD1 . ASN C 1 341 ? 303.565 269.672 244.007 1.00 38.60  ? 341 ASN C OD1 1 
ATOM   8230  N  ND2 . ASN C 1 341 ? 304.198 267.534 243.767 1.00 31.68  ? 341 ASN C ND2 1 
ATOM   8231  N  N   . LYS C 1 342 ? 301.178 269.435 248.369 1.00 30.69  ? 342 LYS C N   1 
ATOM   8232  C  CA  . LYS C 1 342 ? 300.344 268.956 249.463 1.00 31.07  ? 342 LYS C CA  1 
ATOM   8233  C  C   . LYS C 1 342 ? 299.338 267.910 249.008 1.00 26.07  ? 342 LYS C C   1 
ATOM   8234  O  O   . LYS C 1 342 ? 298.920 267.069 249.810 1.00 27.76  ? 342 LYS C O   1 
ATOM   8235  C  CB  . LYS C 1 342 ? 299.600 270.117 250.129 1.00 31.43  ? 342 LYS C CB  1 
ATOM   8236  C  CG  . LYS C 1 342 ? 300.349 270.746 251.290 1.00 39.83  ? 342 LYS C CG  1 
ATOM   8237  C  CD  . LYS C 1 342 ? 300.118 272.243 251.355 1.00 49.26  ? 342 LYS C CD  1 
ATOM   8238  C  CE  . LYS C 1 342 ? 298.722 272.552 251.875 1.00 59.04  ? 342 LYS C CE  1 
ATOM   8239  N  NZ  . LYS C 1 342 ? 298.681 272.636 253.361 1.00 60.39  ? 342 LYS C NZ  1 
ATOM   8240  N  N   . TYR C 1 343 ? 298.944 267.947 247.741 1.00 27.08  ? 343 TYR C N   1 
ATOM   8241  C  CA  . TYR C 1 343 ? 297.980 267.004 247.197 1.00 25.43  ? 343 TYR C CA  1 
ATOM   8242  C  C   . TYR C 1 343 ? 298.612 266.259 246.031 1.00 26.41  ? 343 TYR C C   1 
ATOM   8243  O  O   . TYR C 1 343 ? 299.732 266.587 245.620 1.00 30.70  ? 343 TYR C O   1 
ATOM   8244  C  CB  . TYR C 1 343 ? 296.713 267.727 246.742 1.00 26.27  ? 343 TYR C CB  1 
ATOM   8245  C  CG  . TYR C 1 343 ? 296.029 268.531 247.822 1.00 25.75  ? 343 TYR C CG  1 
ATOM   8246  C  CD1 . TYR C 1 343 ? 295.190 267.922 248.743 1.00 28.98  ? 343 TYR C CD1 1 
ATOM   8247  C  CD2 . TYR C 1 343 ? 296.209 269.904 247.909 1.00 24.88  ? 343 TYR C CD2 1 
ATOM   8248  C  CE1 . TYR C 1 343 ? 294.559 268.656 249.726 1.00 29.10  ? 343 TYR C CE1 1 
ATOM   8249  C  CE2 . TYR C 1 343 ? 295.582 270.646 248.887 1.00 32.60  ? 343 TYR C CE2 1 
ATOM   8250  C  CZ  . TYR C 1 343 ? 294.759 270.018 249.794 1.00 33.88  ? 343 TYR C CZ  1 
ATOM   8251  O  OH  . TYR C 1 343 ? 294.133 270.756 250.771 1.00 36.68  ? 343 TYR C OH  1 
ATOM   8252  N  N   . PRO C 1 344 ? 297.942 265.251 245.476 1.00 24.22  ? 344 PRO C N   1 
ATOM   8253  C  CA  . PRO C 1 344 ? 298.496 264.563 244.304 1.00 26.06  ? 344 PRO C CA  1 
ATOM   8254  C  C   . PRO C 1 344 ? 298.294 265.353 243.021 1.00 28.64  ? 344 PRO C C   1 
ATOM   8255  O  O   . PRO C 1 344 ? 297.885 264.800 241.996 1.00 30.83  ? 344 PRO C O   1 
ATOM   8256  C  CB  . PRO C 1 344 ? 297.721 263.238 244.275 1.00 21.01  ? 344 PRO C CB  1 
ATOM   8257  C  CG  . PRO C 1 344 ? 297.041 263.139 245.608 1.00 19.41  ? 344 PRO C CG  1 
ATOM   8258  C  CD  . PRO C 1 344 ? 296.782 264.540 246.029 1.00 22.03  ? 344 PRO C CD  1 
ATOM   8259  N  N   . TRP C 1 345 ? 298.580 266.651 243.073 1.00 29.11  ? 345 TRP C N   1 
ATOM   8260  C  CA  . TRP C 1 345 ? 298.561 267.499 241.890 1.00 30.32  ? 345 TRP C CA  1 
ATOM   8261  C  C   . TRP C 1 345 ? 299.423 268.722 242.163 1.00 38.17  ? 345 TRP C C   1 
ATOM   8262  O  O   . TRP C 1 345 ? 299.650 269.100 243.315 1.00 37.44  ? 345 TRP C O   1 
ATOM   8263  C  CB  . TRP C 1 345 ? 297.134 267.900 241.495 1.00 29.80  ? 345 TRP C CB  1 
ATOM   8264  C  CG  . TRP C 1 345 ? 296.296 268.411 242.624 1.00 26.93  ? 345 TRP C CG  1 
ATOM   8265  C  CD1 . TRP C 1 345 ? 296.329 269.656 243.172 1.00 30.80  ? 345 TRP C CD1 1 
ATOM   8266  C  CD2 . TRP C 1 345 ? 295.288 267.686 243.336 1.00 27.87  ? 345 TRP C CD2 1 
ATOM   8267  N  NE1 . TRP C 1 345 ? 295.409 269.753 244.185 1.00 30.08  ? 345 TRP C NE1 1 
ATOM   8268  C  CE2 . TRP C 1 345 ? 294.755 268.556 244.305 1.00 28.62  ? 345 TRP C CE2 1 
ATOM   8269  C  CE3 . TRP C 1 345 ? 294.784 266.385 243.248 1.00 22.44  ? 345 TRP C CE3 1 
ATOM   8270  C  CZ2 . TRP C 1 345 ? 293.746 268.167 245.182 1.00 25.37  ? 345 TRP C CZ2 1 
ATOM   8271  C  CZ3 . TRP C 1 345 ? 293.784 266.002 244.118 1.00 24.41  ? 345 TRP C CZ3 1 
ATOM   8272  C  CH2 . TRP C 1 345 ? 293.276 266.888 245.072 1.00 24.26  ? 345 TRP C CH2 1 
ATOM   8273  N  N   . SER C 1 346 ? 299.902 269.335 241.080 1.00 44.43  ? 346 SER C N   1 
ATOM   8274  C  CA  . SER C 1 346 ? 300.849 270.439 241.209 1.00 45.57  ? 346 SER C CA  1 
ATOM   8275  C  C   . SER C 1 346 ? 300.213 271.653 241.873 1.00 49.69  ? 346 SER C C   1 
ATOM   8276  O  O   . SER C 1 346 ? 300.835 272.298 242.725 1.00 49.93  ? 346 SER C O   1 
ATOM   8277  C  CB  . SER C 1 346 ? 301.406 270.813 239.836 1.00 50.35  ? 346 SER C CB  1 
ATOM   8278  O  OG  . SER C 1 346 ? 300.566 271.750 239.186 1.00 56.06  ? 346 SER C OG  1 
ATOM   8279  N  N   . THR C 1 347 ? 298.981 271.981 241.500 1.00 49.25  ? 347 THR C N   1 
ATOM   8280  C  CA  . THR C 1 347 ? 298.347 273.184 242.014 1.00 53.54  ? 347 THR C CA  1 
ATOM   8281  C  C   . THR C 1 347 ? 298.044 273.038 243.503 1.00 56.70  ? 347 THR C C   1 
ATOM   8282  O  O   . THR C 1 347 ? 297.943 271.934 244.042 1.00 57.59  ? 347 THR C O   1 
ATOM   8283  C  CB  . THR C 1 347 ? 297.062 273.485 241.241 1.00 59.63  ? 347 THR C CB  1 
ATOM   8284  O  OG1 . THR C 1 347 ? 296.287 274.455 241.953 1.00 64.09  ? 347 THR C OG1 1 
ATOM   8285  C  CG2 . THR C 1 347 ? 296.239 272.219 241.063 1.00 47.50  ? 347 THR C CG2 1 
ATOM   8286  N  N   . GLU C 1 348 ? 297.912 274.182 244.173 1.00 58.94  ? 348 GLU C N   1 
ATOM   8287  C  CA  . GLU C 1 348 ? 297.571 274.212 245.588 1.00 61.88  ? 348 GLU C CA  1 
ATOM   8288  C  C   . GLU C 1 348 ? 296.074 274.319 245.840 1.00 60.92  ? 348 GLU C C   1 
ATOM   8289  O  O   . GLU C 1 348 ? 295.647 274.209 246.994 1.00 60.59  ? 348 GLU C O   1 
ATOM   8290  C  CB  . GLU C 1 348 ? 298.287 275.377 246.279 1.00 66.67  ? 348 GLU C CB  1 
ATOM   8291  C  CG  . GLU C 1 348 ? 298.965 274.995 247.582 1.00 68.92  ? 348 GLU C CG  1 
ATOM   8292  C  CD  . GLU C 1 348 ? 297.972 274.658 248.675 1.00 68.60  ? 348 GLU C CD  1 
ATOM   8293  O  OE1 . GLU C 1 348 ? 296.992 275.413 248.845 1.00 68.54  ? 348 GLU C OE1 1 
ATOM   8294  O  OE2 . GLU C 1 348 ? 298.162 273.629 249.354 1.00 62.60  ? 348 GLU C OE2 1 
ATOM   8295  N  N   . ASP C 1 349 ? 295.271 274.526 244.802 1.00 59.63  ? 349 ASP C N   1 
ATOM   8296  C  CA  . ASP C 1 349 ? 293.830 274.603 244.970 1.00 55.38  ? 349 ASP C CA  1 
ATOM   8297  C  C   . ASP C 1 349 ? 293.229 273.200 244.983 1.00 51.49  ? 349 ASP C C   1 
ATOM   8298  O  O   . ASP C 1 349 ? 293.935 272.188 244.960 1.00 53.22  ? 349 ASP C O   1 
ATOM   8299  C  CB  . ASP C 1 349 ? 293.211 275.459 243.868 1.00 60.83  ? 349 ASP C CB  1 
ATOM   8300  C  CG  . ASP C 1 349 ? 294.111 276.601 243.439 1.00 70.59  ? 349 ASP C CG  1 
ATOM   8301  O  OD1 . ASP C 1 349 ? 294.531 276.618 242.262 1.00 69.21  ? 349 ASP C OD1 1 
ATOM   8302  O  OD2 . ASP C 1 349 ? 294.402 277.480 244.277 1.00 72.90  ? 349 ASP C OD2 1 
ATOM   8303  N  N   . LEU C 1 350 ? 291.900 273.138 245.029 1.00 43.67  ? 350 LEU C N   1 
ATOM   8304  C  CA  . LEU C 1 350 ? 291.178 271.877 244.977 1.00 37.68  ? 350 LEU C CA  1 
ATOM   8305  C  C   . LEU C 1 350 ? 290.310 271.749 243.734 1.00 38.69  ? 350 LEU C C   1 
ATOM   8306  O  O   . LEU C 1 350 ? 289.661 270.713 243.554 1.00 39.68  ? 350 LEU C O   1 
ATOM   8307  C  CB  . LEU C 1 350 ? 290.312 271.706 246.232 1.00 31.03  ? 350 LEU C CB  1 
ATOM   8308  C  CG  . LEU C 1 350 ? 291.056 271.572 247.563 1.00 33.63  ? 350 LEU C CG  1 
ATOM   8309  C  CD1 . LEU C 1 350 ? 290.281 272.248 248.679 1.00 34.62  ? 350 LEU C CD1 1 
ATOM   8310  C  CD2 . LEU C 1 350 ? 291.313 270.112 247.897 1.00 32.33  ? 350 LEU C CD2 1 
ATOM   8311  N  N   . ARG C 1 351 ? 290.283 272.765 242.875 1.00 42.17  ? 351 ARG C N   1 
ATOM   8312  C  CA  . ARG C 1 351 ? 289.515 272.740 241.641 1.00 40.79  ? 351 ARG C CA  1 
ATOM   8313  C  C   . ARG C 1 351 ? 290.387 273.222 240.493 1.00 41.06  ? 351 ARG C C   1 
ATOM   8314  O  O   . ARG C 1 351 ? 291.354 273.963 240.688 1.00 46.26  ? 351 ARG C O   1 
ATOM   8315  C  CB  . ARG C 1 351 ? 288.260 273.616 241.738 1.00 41.81  ? 351 ARG C CB  1 
ATOM   8316  C  CG  . ARG C 1 351 ? 287.522 273.493 243.051 1.00 38.47  ? 351 ARG C CG  1 
ATOM   8317  C  CD  . ARG C 1 351 ? 286.715 274.740 243.337 1.00 44.98  ? 351 ARG C CD  1 
ATOM   8318  N  NE  . ARG C 1 351 ? 285.353 274.627 242.831 1.00 48.61  ? 351 ARG C NE  1 
ATOM   8319  C  CZ  . ARG C 1 351 ? 284.275 275.000 243.504 1.00 51.67  ? 351 ARG C CZ  1 
ATOM   8320  N  NH1 . ARG C 1 351 ? 284.364 275.517 244.719 1.00 54.14  ? 351 ARG C NH1 1 
ATOM   8321  N  NH2 . ARG C 1 351 ? 283.078 274.849 242.947 1.00 50.91  ? 351 ARG C NH2 1 
ATOM   8322  N  N   . THR C 1 352 ? 290.035 272.789 239.287 1.00 46.08  ? 352 THR C N   1 
ATOM   8323  C  CA  . THR C 1 352 ? 290.708 273.263 238.089 1.00 49.72  ? 352 THR C CA  1 
ATOM   8324  C  C   . THR C 1 352 ? 290.291 274.702 237.792 1.00 57.39  ? 352 THR C C   1 
ATOM   8325  O  O   . THR C 1 352 ? 289.495 275.313 238.510 1.00 58.11  ? 352 THR C O   1 
ATOM   8326  C  CB  . THR C 1 352 ? 290.397 272.354 236.904 1.00 49.55  ? 352 THR C CB  1 
ATOM   8327  O  OG1 . THR C 1 352 ? 289.156 272.752 236.310 1.00 58.96  ? 352 THR C OG1 1 
ATOM   8328  C  CG2 . THR C 1 352 ? 290.294 270.909 237.353 1.00 47.77  ? 352 THR C CG2 1 
ATOM   8329  N  N   . GLY C 1 353 ? 290.841 275.251 236.709 1.00 58.74  ? 353 GLY C N   1 
ATOM   8330  C  CA  . GLY C 1 353 ? 290.502 276.612 236.333 1.00 59.36  ? 353 GLY C CA  1 
ATOM   8331  C  C   . GLY C 1 353 ? 289.030 276.796 236.024 1.00 60.05  ? 353 GLY C C   1 
ATOM   8332  O  O   . GLY C 1 353 ? 288.503 277.906 236.134 1.00 62.06  ? 353 GLY C O   1 
ATOM   8333  N  N   . ARG C 1 354 ? 288.349 275.721 235.638 1.00 61.70  ? 354 ARG C N   1 
ATOM   8334  C  CA  . ARG C 1 354 ? 286.933 275.765 235.300 1.00 60.48  ? 354 ARG C CA  1 
ATOM   8335  C  C   . ARG C 1 354 ? 286.031 275.394 236.472 1.00 57.44  ? 354 ARG C C   1 
ATOM   8336  O  O   . ARG C 1 354 ? 284.815 275.283 236.289 1.00 60.14  ? 354 ARG C O   1 
ATOM   8337  C  CB  . ARG C 1 354 ? 286.650 274.842 234.114 1.00 64.70  ? 354 ARG C CB  1 
ATOM   8338  C  CG  . ARG C 1 354 ? 287.701 274.913 233.019 1.00 70.05  ? 354 ARG C CG  1 
ATOM   8339  C  CD  . ARG C 1 354 ? 287.080 274.783 231.638 1.00 77.71  ? 354 ARG C CD  1 
ATOM   8340  N  NE  . ARG C 1 354 ? 285.935 273.881 231.641 1.00 87.42  ? 354 ARG C NE  1 
ATOM   8341  C  CZ  . ARG C 1 354 ? 286.027 272.559 231.635 1.00 83.55  ? 354 ARG C CZ  1 
ATOM   8342  N  NH1 . ARG C 1 354 ? 287.200 271.947 231.621 1.00 80.26  ? 354 ARG C NH1 1 
ATOM   8343  N  NH2 . ARG C 1 354 ? 284.913 271.831 231.646 1.00 77.86  ? 354 ARG C NH2 1 
ATOM   8344  N  N   . GLY C 1 355 ? 286.594 275.196 237.660 1.00 53.54  ? 355 GLY C N   1 
ATOM   8345  C  CA  . GLY C 1 355 ? 285.805 274.895 238.835 1.00 49.56  ? 355 GLY C CA  1 
ATOM   8346  C  C   . GLY C 1 355 ? 285.564 273.429 239.110 1.00 51.51  ? 355 GLY C C   1 
ATOM   8347  O  O   . GLY C 1 355 ? 284.818 273.108 240.042 1.00 48.95  ? 355 GLY C O   1 
ATOM   8348  N  N   . CYS C 1 356 ? 286.166 272.528 238.338 1.00 49.16  ? 356 CYS C N   1 
ATOM   8349  C  CA  . CYS C 1 356 ? 285.984 271.101 238.558 1.00 42.91  ? 356 CYS C CA  1 
ATOM   8350  C  C   . CYS C 1 356 ? 286.921 270.615 239.656 1.00 38.60  ? 356 CYS C C   1 
ATOM   8351  O  O   . CYS C 1 356 ? 288.120 270.907 239.636 1.00 39.76  ? 356 CYS C O   1 
ATOM   8352  C  CB  . CYS C 1 356 ? 286.237 270.326 237.266 1.00 49.40  ? 356 CYS C CB  1 
ATOM   8353  S  SG  . CYS C 1 356 ? 285.111 270.735 235.916 1.00 70.25  ? 356 CYS C SG  1 
ATOM   8354  N  N   . PHE C 1 357 ? 286.375 269.869 240.611 1.00 35.19  ? 357 PHE C N   1 
ATOM   8355  C  CA  . PHE C 1 357 ? 287.186 269.338 241.696 1.00 32.03  ? 357 PHE C CA  1 
ATOM   8356  C  C   . PHE C 1 357 ? 288.143 268.270 241.177 1.00 30.64  ? 357 PHE C C   1 
ATOM   8357  O  O   . PHE C 1 357 ? 287.884 267.604 240.172 1.00 33.71  ? 357 PHE C O   1 
ATOM   8358  C  CB  . PHE C 1 357 ? 286.295 268.766 242.798 1.00 28.99  ? 357 PHE C CB  1 
ATOM   8359  C  CG  . PHE C 1 357 ? 285.642 269.814 243.652 1.00 30.40  ? 357 PHE C CG  1 
ATOM   8360  C  CD1 . PHE C 1 357 ? 286.321 270.381 244.716 1.00 27.61  ? 357 PHE C CD1 1 
ATOM   8361  C  CD2 . PHE C 1 357 ? 284.353 270.237 243.386 1.00 29.54  ? 357 PHE C CD2 1 
ATOM   8362  C  CE1 . PHE C 1 357 ? 285.724 271.346 245.500 1.00 28.17  ? 357 PHE C CE1 1 
ATOM   8363  C  CE2 . PHE C 1 357 ? 283.751 271.201 244.166 1.00 25.89  ? 357 PHE C CE2 1 
ATOM   8364  C  CZ  . PHE C 1 357 ? 284.438 271.756 245.223 1.00 30.24  ? 357 PHE C CZ  1 
ATOM   8365  N  N   . LEU C 1 358 ? 289.266 268.117 241.875 1.00 27.97  ? 358 LEU C N   1 
ATOM   8366  C  CA  . LEU C 1 358 ? 290.326 267.207 241.466 1.00 25.63  ? 358 LEU C CA  1 
ATOM   8367  C  C   . LEU C 1 358 ? 290.235 265.842 242.131 1.00 27.25  ? 358 LEU C C   1 
ATOM   8368  O  O   . LEU C 1 358 ? 291.065 264.973 241.848 1.00 30.98  ? 358 LEU C O   1 
ATOM   8369  C  CB  . LEU C 1 358 ? 291.693 267.833 241.756 1.00 29.23  ? 358 LEU C CB  1 
ATOM   8370  C  CG  . LEU C 1 358 ? 292.033 269.067 240.920 1.00 31.59  ? 358 LEU C CG  1 
ATOM   8371  C  CD1 . LEU C 1 358 ? 293.184 269.834 241.540 1.00 32.82  ? 358 LEU C CD1 1 
ATOM   8372  C  CD2 . LEU C 1 358 ? 292.355 268.670 239.491 1.00 30.47  ? 358 LEU C CD2 1 
ATOM   8373  N  N   . GLY C 1 359 ? 289.253 265.628 243.001 1.00 25.70  ? 359 GLY C N   1 
ATOM   8374  C  CA  . GLY C 1 359 ? 289.104 264.353 243.671 1.00 16.67  ? 359 GLY C CA  1 
ATOM   8375  C  C   . GLY C 1 359 ? 287.686 264.188 244.167 1.00 18.80  ? 359 GLY C C   1 
ATOM   8376  O  O   . GLY C 1 359 ? 286.855 265.090 244.052 1.00 22.86  ? 359 GLY C O   1 
ATOM   8377  N  N   . ASN C 1 360 ? 287.419 263.014 244.730 1.00 15.70  ? 360 ASN C N   1 
ATOM   8378  C  CA  . ASN C 1 360 ? 286.095 262.656 245.232 1.00 15.46  ? 360 ASN C CA  1 
ATOM   8379  C  C   . ASN C 1 360 ? 286.156 262.628 246.756 1.00 17.15  ? 360 ASN C C   1 
ATOM   8380  O  O   . ASN C 1 360 ? 286.559 261.628 247.353 1.00 18.19  ? 360 ASN C O   1 
ATOM   8381  C  CB  . ASN C 1 360 ? 285.643 261.315 244.664 1.00 16.86  ? 360 ASN C CB  1 
ATOM   8382  C  CG  . ASN C 1 360 ? 284.340 260.834 245.268 1.00 18.79  ? 360 ASN C CG  1 
ATOM   8383  O  OD1 . ASN C 1 360 ? 283.561 261.619 245.806 1.00 22.53  ? 360 ASN C OD1 1 
ATOM   8384  N  ND2 . ASN C 1 360 ? 284.098 259.533 245.184 1.00 20.94  ? 360 ASN C ND2 1 
ATOM   8385  N  N   . PHE C 1 361 ? 285.747 263.728 247.377 1.00 15.96  ? 361 PHE C N   1 
ATOM   8386  C  CA  . PHE C 1 361 ? 285.739 263.857 248.829 1.00 16.49  ? 361 PHE C CA  1 
ATOM   8387  C  C   . PHE C 1 361 ? 284.478 264.623 249.216 1.00 17.97  ? 361 PHE C C   1 
ATOM   8388  O  O   . PHE C 1 361 ? 283.552 264.786 248.414 1.00 27.13  ? 361 PHE C O   1 
ATOM   8389  C  CB  . PHE C 1 361 ? 287.033 264.525 249.324 1.00 19.50  ? 361 PHE C CB  1 
ATOM   8390  C  CG  . PHE C 1 361 ? 287.143 265.982 248.970 1.00 19.80  ? 361 PHE C CG  1 
ATOM   8391  C  CD1 . PHE C 1 361 ? 287.214 266.385 247.649 1.00 15.69  ? 361 PHE C CD1 1 
ATOM   8392  C  CD2 . PHE C 1 361 ? 287.178 266.949 249.960 1.00 17.31  ? 361 PHE C CD2 1 
ATOM   8393  C  CE1 . PHE C 1 361 ? 287.314 267.719 247.322 1.00 18.37  ? 361 PHE C CE1 1 
ATOM   8394  C  CE2 . PHE C 1 361 ? 287.277 268.284 249.639 1.00 16.74  ? 361 PHE C CE2 1 
ATOM   8395  C  CZ  . PHE C 1 361 ? 287.346 268.670 248.319 1.00 18.93  ? 361 PHE C CZ  1 
ATOM   8396  N  N   . LYS C 1 362 ? 284.425 265.090 250.459 1.00 19.97  ? 362 LYS C N   1 
ATOM   8397  C  CA  . LYS C 1 362 ? 283.297 265.869 250.951 1.00 20.88  ? 362 LYS C CA  1 
ATOM   8398  C  C   . LYS C 1 362 ? 283.674 267.345 250.996 1.00 23.13  ? 362 LYS C C   1 
ATOM   8399  O  O   . LYS C 1 362 ? 284.160 267.831 252.024 1.00 27.32  ? 362 LYS C O   1 
ATOM   8400  C  CB  . LYS C 1 362 ? 282.876 265.376 252.336 1.00 18.29  ? 362 LYS C CB  1 
ATOM   8401  C  CG  . LYS C 1 362 ? 281.682 266.093 252.927 1.00 24.51  ? 362 LYS C CG  1 
ATOM   8402  C  CD  . LYS C 1 362 ? 281.532 265.759 254.400 1.00 25.11  ? 362 LYS C CD  1 
ATOM   8403  C  CE  . LYS C 1 362 ? 280.240 266.312 254.967 1.00 26.07  ? 362 LYS C CE  1 
ATOM   8404  N  NZ  . LYS C 1 362 ? 279.905 265.681 256.270 1.00 31.28  ? 362 LYS C NZ  1 
ATOM   8405  N  N   . PRO C 1 363 ? 283.469 268.089 249.905 1.00 23.74  ? 363 PRO C N   1 
ATOM   8406  C  CA  . PRO C 1 363 ? 283.957 269.475 249.851 1.00 24.67  ? 363 PRO C CA  1 
ATOM   8407  C  C   . PRO C 1 363 ? 283.118 270.458 250.652 1.00 26.48  ? 363 PRO C C   1 
ATOM   8408  O  O   . PRO C 1 363 ? 283.649 271.437 251.183 1.00 31.37  ? 363 PRO C O   1 
ATOM   8409  C  CB  . PRO C 1 363 ? 283.909 269.806 248.351 1.00 24.38  ? 363 PRO C CB  1 
ATOM   8410  C  CG  . PRO C 1 363 ? 283.700 268.501 247.651 1.00 18.80  ? 363 PRO C CG  1 
ATOM   8411  C  CD  . PRO C 1 363 ? 282.954 267.639 248.604 1.00 22.22  ? 363 PRO C CD  1 
ATOM   8412  N  N   . GLY C 1 364 ? 281.812 270.224 250.739 1.00 25.00  ? 364 GLY C N   1 
ATOM   8413  C  CA  . GLY C 1 364 ? 280.940 271.147 251.436 1.00 23.98  ? 364 GLY C CA  1 
ATOM   8414  C  C   . GLY C 1 364 ? 280.333 270.574 252.698 1.00 25.94  ? 364 GLY C C   1 
ATOM   8415  O  O   . GLY C 1 364 ? 280.354 269.358 252.906 1.00 29.27  ? 364 GLY C O   1 
ATOM   8416  N  N   . GLU C 1 365 ? 279.785 271.438 253.548 1.00 28.12  ? 365 GLU C N   1 
ATOM   8417  C  CA  . GLU C 1 365 ? 279.161 270.982 254.783 1.00 28.25  ? 365 GLU C CA  1 
ATOM   8418  C  C   . GLU C 1 365 ? 277.900 270.193 254.460 1.00 31.99  ? 365 GLU C C   1 
ATOM   8419  O  O   . GLU C 1 365 ? 276.926 270.749 253.944 1.00 36.13  ? 365 GLU C O   1 
ATOM   8420  C  CB  . GLU C 1 365 ? 278.833 272.168 255.682 1.00 28.51  ? 365 GLU C CB  1 
ATOM   8421  C  CG  . GLU C 1 365 ? 278.015 271.797 256.905 1.00 36.97  ? 365 GLU C CG  1 
ATOM   8422  C  CD  . GLU C 1 365 ? 277.845 272.956 257.861 1.00 52.50  ? 365 GLU C CD  1 
ATOM   8423  O  OE1 . GLU C 1 365 ? 277.958 274.115 257.413 1.00 57.93  ? 365 GLU C OE1 1 
ATOM   8424  O  OE2 . GLU C 1 365 ? 277.593 272.709 259.058 1.00 54.55  ? 365 GLU C OE2 1 
ATOM   8425  N  N   . GLY C 1 366 ? 277.917 268.899 254.765 1.00 30.62  ? 366 GLY C N   1 
ATOM   8426  C  CA  . GLY C 1 366 ? 276.811 268.036 254.406 1.00 25.70  ? 366 GLY C CA  1 
ATOM   8427  C  C   . GLY C 1 366 ? 276.673 267.913 252.904 1.00 28.40  ? 366 GLY C C   1 
ATOM   8428  O  O   . GLY C 1 366 ? 275.656 267.431 252.401 1.00 31.93  ? 366 GLY C O   1 
ATOM   8429  N  N   . ASP C 1 367 ? 277.700 268.349 252.179 1.00 29.74  ? 367 ASP C N   1 
ATOM   8430  C  CA  . ASP C 1 367 ? 277.690 268.413 250.719 1.00 24.57  ? 367 ASP C CA  1 
ATOM   8431  C  C   . ASP C 1 367 ? 278.773 267.478 250.191 1.00 24.63  ? 367 ASP C C   1 
ATOM   8432  O  O   . ASP C 1 367 ? 279.902 267.894 249.926 1.00 29.16  ? 367 ASP C O   1 
ATOM   8433  C  CB  . ASP C 1 367 ? 277.906 269.856 250.255 1.00 28.22  ? 367 ASP C CB  1 
ATOM   8434  C  CG  . ASP C 1 367 ? 277.831 270.005 248.754 1.00 34.56  ? 367 ASP C CG  1 
ATOM   8435  O  OD1 . ASP C 1 367 ? 277.750 268.979 248.051 1.00 38.36  ? 367 ASP C OD1 1 
ATOM   8436  O  OD2 . ASP C 1 367 ? 277.863 271.155 248.272 1.00 38.75  ? 367 ASP C OD2 1 
ATOM   8437  N  N   . TYR C 1 368 ? 278.418 266.201 250.038 1.00 28.26  ? 368 TYR C N   1 
ATOM   8438  C  CA  . TYR C 1 368 ? 279.337 265.234 249.452 1.00 24.43  ? 368 TYR C CA  1 
ATOM   8439  C  C   . TYR C 1 368 ? 279.390 265.338 247.934 1.00 24.57  ? 368 TYR C C   1 
ATOM   8440  O  O   . TYR C 1 368 ? 280.443 265.091 247.337 1.00 28.91  ? 368 TYR C O   1 
ATOM   8441  C  CB  . TYR C 1 368 ? 278.936 263.810 249.842 1.00 22.00  ? 368 TYR C CB  1 
ATOM   8442  C  CG  . TYR C 1 368 ? 278.938 263.524 251.326 1.00 24.67  ? 368 TYR C CG  1 
ATOM   8443  C  CD1 . TYR C 1 368 ? 277.882 263.926 252.131 1.00 23.63  ? 368 TYR C CD1 1 
ATOM   8444  C  CD2 . TYR C 1 368 ? 279.986 262.833 251.919 1.00 24.28  ? 368 TYR C CD2 1 
ATOM   8445  C  CE1 . TYR C 1 368 ? 277.874 263.659 253.485 1.00 24.93  ? 368 TYR C CE1 1 
ATOM   8446  C  CE2 . TYR C 1 368 ? 279.987 262.562 253.272 1.00 23.25  ? 368 TYR C CE2 1 
ATOM   8447  C  CZ  . TYR C 1 368 ? 278.929 262.977 254.050 1.00 27.49  ? 368 TYR C CZ  1 
ATOM   8448  O  OH  . TYR C 1 368 ? 278.925 262.708 255.396 1.00 34.75  ? 368 TYR C OH  1 
ATOM   8449  N  N   . THR C 1 369 ? 278.277 265.697 247.301 1.00 24.54  ? 369 THR C N   1 
ATOM   8450  C  CA  . THR C 1 369 ? 278.128 265.596 245.855 1.00 25.90  ? 369 THR C CA  1 
ATOM   8451  C  C   . THR C 1 369 ? 278.691 266.792 245.098 1.00 25.44  ? 369 THR C C   1 
ATOM   8452  O  O   . THR C 1 369 ? 278.522 266.858 243.878 1.00 25.81  ? 369 THR C O   1 
ATOM   8453  C  CB  . THR C 1 369 ? 276.650 265.415 245.493 1.00 24.32  ? 369 THR C CB  1 
ATOM   8454  O  OG1 . THR C 1 369 ? 275.890 266.512 246.014 1.00 32.45  ? 369 THR C OG1 1 
ATOM   8455  C  CG2 . THR C 1 369 ? 276.114 264.121 246.076 1.00 20.64  ? 369 THR C CG2 1 
ATOM   8456  N  N   . ALA C 1 370 ? 279.350 267.732 245.779 1.00 26.57  ? 370 ALA C N   1 
ATOM   8457  C  CA  . ALA C 1 370 ? 279.867 268.909 245.089 1.00 24.04  ? 370 ALA C CA  1 
ATOM   8458  C  C   . ALA C 1 370 ? 280.822 268.534 243.963 1.00 24.94  ? 370 ALA C C   1 
ATOM   8459  O  O   . ALA C 1 370 ? 280.949 269.279 242.985 1.00 24.57  ? 370 ALA C O   1 
ATOM   8460  C  CB  . ALA C 1 370 ? 280.558 269.840 246.083 1.00 22.32  ? 370 ALA C CB  1 
ATOM   8461  N  N   . ASP C 1 371 ? 281.494 267.390 244.073 1.00 22.99  ? 371 ASP C N   1 
ATOM   8462  C  CA  . ASP C 1 371 ? 282.394 266.913 243.032 1.00 21.98  ? 371 ASP C CA  1 
ATOM   8463  C  C   . ASP C 1 371 ? 281.723 265.949 242.062 1.00 25.01  ? 371 ASP C C   1 
ATOM   8464  O  O   . ASP C 1 371 ? 282.391 265.440 241.157 1.00 27.73  ? 371 ASP C O   1 
ATOM   8465  C  CB  . ASP C 1 371 ? 283.622 266.241 243.655 1.00 21.19  ? 371 ASP C CB  1 
ATOM   8466  C  CG  . ASP C 1 371 ? 283.293 265.471 244.915 1.00 23.33  ? 371 ASP C CG  1 
ATOM   8467  O  OD1 . ASP C 1 371 ? 282.285 264.736 244.929 1.00 25.48  ? 371 ASP C OD1 1 
ATOM   8468  O  OD2 . ASP C 1 371 ? 284.055 265.593 245.894 1.00 29.56  ? 371 ASP C OD2 1 
ATOM   8469  N  N   . GLY C 1 372 ? 280.427 265.694 242.221 1.00 23.72  ? 372 GLY C N   1 
ATOM   8470  C  CA  . GLY C 1 372 ? 279.693 264.817 241.338 1.00 17.87  ? 372 GLY C CA  1 
ATOM   8471  C  C   . GLY C 1 372 ? 279.370 263.454 241.909 1.00 22.99  ? 372 GLY C C   1 
ATOM   8472  O  O   . GLY C 1 372 ? 278.547 262.739 241.327 1.00 27.68  ? 372 GLY C O   1 
ATOM   8473  N  N   . HIS C 1 373 ? 279.986 263.072 243.024 1.00 24.33  ? 373 HIS C N   1 
ATOM   8474  C  CA  . HIS C 1 373 ? 279.803 261.742 243.583 1.00 21.30  ? 373 HIS C CA  1 
ATOM   8475  C  C   . HIS C 1 373 ? 279.560 261.837 245.080 1.00 21.58  ? 373 HIS C C   1 
ATOM   8476  O  O   . HIS C 1 373 ? 280.212 262.619 245.775 1.00 30.78  ? 373 HIS C O   1 
ATOM   8477  C  CB  . HIS C 1 373 ? 281.020 260.855 243.302 1.00 17.81  ? 373 HIS C CB  1 
ATOM   8478  C  CG  . HIS C 1 373 ? 281.493 260.919 241.885 1.00 19.72  ? 373 HIS C CG  1 
ATOM   8479  N  ND1 . HIS C 1 373 ? 281.019 260.075 240.905 1.00 23.06  ? 373 HIS C ND1 1 
ATOM   8480  C  CD2 . HIS C 1 373 ? 282.385 261.737 241.278 1.00 20.46  ? 373 HIS C CD2 1 
ATOM   8481  C  CE1 . HIS C 1 373 ? 281.603 260.366 239.757 1.00 25.46  ? 373 HIS C CE1 1 
ATOM   8482  N  NE2 . HIS C 1 373 ? 282.436 261.371 239.956 1.00 27.80  ? 373 HIS C NE2 1 
ATOM   8483  N  N   . LEU C 1 374 ? 278.617 261.033 245.568 1.00 21.67  ? 374 LEU C N   1 
ATOM   8484  C  CA  . LEU C 1 374 ? 278.337 260.946 246.997 1.00 23.75  ? 374 LEU C CA  1 
ATOM   8485  C  C   . LEU C 1 374 ? 279.168 259.846 247.652 1.00 25.38  ? 374 LEU C C   1 
ATOM   8486  O  O   . LEU C 1 374 ? 279.991 260.118 248.531 1.00 27.55  ? 374 LEU C O   1 
ATOM   8487  C  CB  . LEU C 1 374 ? 276.840 260.702 247.218 1.00 25.05  ? 374 LEU C CB  1 
ATOM   8488  C  CG  . LEU C 1 374 ? 276.370 260.378 248.636 1.00 29.97  ? 374 LEU C CG  1 
ATOM   8489  C  CD1 . LEU C 1 374 ? 276.728 261.494 249.594 1.00 31.28  ? 374 LEU C CD1 1 
ATOM   8490  C  CD2 . LEU C 1 374 ? 274.874 260.119 248.654 1.00 26.36  ? 374 LEU C CD2 1 
ATOM   8491  N  N   . ILE C 1 375 ? 278.965 258.606 247.223 1.00 24.43  ? 375 ILE C N   1 
ATOM   8492  C  CA  . ILE C 1 375 ? 279.771 257.465 247.651 1.00 20.98  ? 375 ILE C CA  1 
ATOM   8493  C  C   . ILE C 1 375 ? 280.930 257.328 246.671 1.00 21.88  ? 375 ILE C C   1 
ATOM   8494  O  O   . ILE C 1 375 ? 281.049 258.150 245.752 1.00 23.38  ? 375 ILE C O   1 
ATOM   8495  C  CB  . ILE C 1 375 ? 278.926 256.184 247.740 1.00 24.73  ? 375 ILE C CB  1 
ATOM   8496  C  CG1 . ILE C 1 375 ? 278.279 255.866 246.391 1.00 24.17  ? 375 ILE C CG1 1 
ATOM   8497  C  CG2 . ILE C 1 375 ? 277.878 256.315 248.835 1.00 21.61  ? 375 ILE C CG2 1 
ATOM   8498  C  CD1 . ILE C 1 375 ? 277.983 254.400 246.196 1.00 21.15  ? 375 ILE C CD1 1 
ATOM   8499  N  N   . PRO C 1 376 ? 281.817 256.336 246.826 1.00 23.58  ? 376 PRO C N   1 
ATOM   8500  C  CA  . PRO C 1 376 ? 282.951 256.219 245.897 1.00 21.26  ? 376 PRO C CA  1 
ATOM   8501  C  C   . PRO C 1 376 ? 282.516 256.218 244.440 1.00 20.33  ? 376 PRO C C   1 
ATOM   8502  O  O   . PRO C 1 376 ? 281.336 256.025 244.135 1.00 27.41  ? 376 PRO C O   1 
ATOM   8503  C  CB  . PRO C 1 376 ? 283.590 254.882 246.289 1.00 15.92  ? 376 PRO C CB  1 
ATOM   8504  C  CG  . PRO C 1 376 ? 283.181 254.659 247.689 1.00 18.96  ? 376 PRO C CG  1 
ATOM   8505  C  CD  . PRO C 1 376 ? 281.833 255.282 247.853 1.00 19.82  ? 376 PRO C CD  1 
ATOM   8506  N  N   . SER C 1 377 ? 283.463 256.430 243.533 1.00 19.11  ? 377 SER C N   1 
ATOM   8507  C  CA  . SER C 1 377 ? 283.179 256.519 242.110 1.00 17.53  ? 377 SER C CA  1 
ATOM   8508  C  C   . SER C 1 377 ? 284.062 255.537 241.354 1.00 19.90  ? 377 SER C C   1 
ATOM   8509  O  O   . SER C 1 377 ? 285.001 254.957 241.901 1.00 25.04  ? 377 SER C O   1 
ATOM   8510  C  CB  . SER C 1 377 ? 283.398 257.942 241.583 1.00 17.55  ? 377 SER C CB  1 
ATOM   8511  O  OG  . SER C 1 377 ? 284.692 258.413 241.910 1.00 20.67  ? 377 SER C OG  1 
ATOM   8512  N  N   . ARG C 1 378 ? 283.737 255.351 240.079 1.00 22.35  ? 378 ARG C N   1 
ATOM   8513  C  CA  . ARG C 1 378 ? 284.537 254.494 239.218 1.00 22.03  ? 378 ARG C CA  1 
ATOM   8514  C  C   . ARG C 1 378 ? 285.982 254.973 239.203 1.00 26.41  ? 378 ARG C C   1 
ATOM   8515  O  O   . ARG C 1 378 ? 286.250 256.170 239.069 1.00 27.47  ? 378 ARG C O   1 
ATOM   8516  C  CB  . ARG C 1 378 ? 283.960 254.497 237.804 1.00 22.51  ? 378 ARG C CB  1 
ATOM   8517  C  CG  . ARG C 1 378 ? 284.317 253.289 236.965 1.00 29.28  ? 378 ARG C CG  1 
ATOM   8518  C  CD  . ARG C 1 378 ? 283.674 253.398 235.594 1.00 40.52  ? 378 ARG C CD  1 
ATOM   8519  N  NE  . ARG C 1 378 ? 282.604 254.389 235.594 1.00 50.52  ? 378 ARG C NE  1 
ATOM   8520  C  CZ  . ARG C 1 378 ? 281.312 254.101 235.679 1.00 52.48  ? 378 ARG C CZ  1 
ATOM   8521  N  NH1 . ARG C 1 378 ? 280.886 252.851 235.752 1.00 49.19  ? 378 ARG C NH1 1 
ATOM   8522  N  NH2 . ARG C 1 378 ? 280.426 255.092 235.695 1.00 47.09  ? 378 ARG C NH2 1 
ATOM   8523  N  N   . VAL C 1 379 ? 286.916 254.031 239.346 1.00 23.44  ? 379 VAL C N   1 
ATOM   8524  C  CA  . VAL C 1 379 ? 288.325 254.389 239.339 1.00 23.47  ? 379 VAL C CA  1 
ATOM   8525  C  C   . VAL C 1 379 ? 288.671 255.080 238.023 1.00 25.85  ? 379 VAL C C   1 
ATOM   8526  O  O   . VAL C 1 379 ? 288.127 254.757 236.960 1.00 28.78  ? 379 VAL C O   1 
ATOM   8527  C  CB  . VAL C 1 379 ? 289.212 253.153 239.568 1.00 23.44  ? 379 VAL C CB  1 
ATOM   8528  C  CG1 . VAL C 1 379 ? 288.772 252.410 240.819 1.00 19.09  ? 379 VAL C CG1 1 
ATOM   8529  C  CG2 . VAL C 1 379 ? 289.178 252.234 238.357 1.00 18.11  ? 379 VAL C CG2 1 
ATOM   8530  N  N   . SER C 1 380 ? 289.585 256.048 238.100 1.00 25.66  ? 380 SER C N   1 
ATOM   8531  C  CA  . SER C 1 380 ? 290.034 256.844 236.963 1.00 24.98  ? 380 SER C CA  1 
ATOM   8532  C  C   . SER C 1 380 ? 289.016 257.890 236.530 1.00 25.72  ? 380 SER C C   1 
ATOM   8533  O  O   . SER C 1 380 ? 289.023 258.311 235.369 1.00 31.14  ? 380 SER C O   1 
ATOM   8534  C  CB  . SER C 1 380 ? 290.393 255.958 235.766 1.00 22.50  ? 380 SER C CB  1 
ATOM   8535  O  OG  . SER C 1 380 ? 291.496 255.125 236.066 1.00 31.98  ? 380 SER C OG  1 
ATOM   8536  N  N   . SER C 1 381 ? 288.134 258.324 237.430 1.00 23.62  ? 381 SER C N   1 
ATOM   8537  C  CA  . SER C 1 381 ? 287.167 259.365 237.107 1.00 22.83  ? 381 SER C CA  1 
ATOM   8538  C  C   . SER C 1 381 ? 287.770 260.762 237.127 1.00 26.90  ? 381 SER C C   1 
ATOM   8539  O  O   . SER C 1 381 ? 287.103 261.712 236.703 1.00 28.44  ? 381 SER C O   1 
ATOM   8540  C  CB  . SER C 1 381 ? 285.986 259.308 238.078 1.00 23.04  ? 381 SER C CB  1 
ATOM   8541  O  OG  . SER C 1 381 ? 285.155 258.196 237.803 1.00 25.88  ? 381 SER C OG  1 
ATOM   8542  N  N   . PHE C 1 382 ? 288.999 260.912 237.611 1.00 24.50  ? 382 PHE C N   1 
ATOM   8543  C  CA  . PHE C 1 382 ? 289.692 262.190 237.637 1.00 19.98  ? 382 PHE C CA  1 
ATOM   8544  C  C   . PHE C 1 382 ? 291.054 262.031 236.979 1.00 25.08  ? 382 PHE C C   1 
ATOM   8545  O  O   . PHE C 1 382 ? 291.476 260.926 236.630 1.00 31.62  ? 382 PHE C O   1 
ATOM   8546  C  CB  . PHE C 1 382 ? 289.839 262.719 239.069 1.00 20.48  ? 382 PHE C CB  1 
ATOM   8547  C  CG  . PHE C 1 382 ? 288.534 262.873 239.792 1.00 22.92  ? 382 PHE C CG  1 
ATOM   8548  C  CD1 . PHE C 1 382 ? 287.922 261.783 240.383 1.00 20.66  ? 382 PHE C CD1 1 
ATOM   8549  C  CD2 . PHE C 1 382 ? 287.918 264.108 239.876 1.00 22.21  ? 382 PHE C CD2 1 
ATOM   8550  C  CE1 . PHE C 1 382 ? 286.722 261.922 241.042 1.00 19.42  ? 382 PHE C CE1 1 
ATOM   8551  C  CE2 . PHE C 1 382 ? 286.719 264.252 240.537 1.00 17.34  ? 382 PHE C CE2 1 
ATOM   8552  C  CZ  . PHE C 1 382 ? 286.120 263.158 241.120 1.00 19.18  ? 382 PHE C CZ  1 
ATOM   8553  N  N   . SER C 1 383 ? 291.741 263.154 236.802 1.00 28.35  ? 383 SER C N   1 
ATOM   8554  C  CA  . SER C 1 383 ? 293.050 263.131 236.175 1.00 24.73  ? 383 SER C CA  1 
ATOM   8555  C  C   . SER C 1 383 ? 294.059 262.422 237.078 1.00 23.40  ? 383 SER C C   1 
ATOM   8556  O  O   . SER C 1 383 ? 293.963 262.493 238.306 1.00 27.13  ? 383 SER C O   1 
ATOM   8557  C  CB  . SER C 1 383 ? 293.521 264.551 235.877 1.00 26.77  ? 383 SER C CB  1 
ATOM   8558  O  OG  . SER C 1 383 ? 294.338 264.585 234.722 1.00 41.22  ? 383 SER C OG  1 
ATOM   8559  N  N   . PRO C 1 384 ? 295.035 261.725 236.496 1.00 25.04  ? 384 PRO C N   1 
ATOM   8560  C  CA  . PRO C 1 384 ? 295.996 260.986 237.321 1.00 23.04  ? 384 PRO C CA  1 
ATOM   8561  C  C   . PRO C 1 384 ? 297.151 261.843 237.810 1.00 23.46  ? 384 PRO C C   1 
ATOM   8562  O  O   . PRO C 1 384 ? 297.198 263.054 237.572 1.00 25.37  ? 384 PRO C O   1 
ATOM   8563  C  CB  . PRO C 1 384 ? 296.482 259.886 236.373 1.00 20.89  ? 384 PRO C CB  1 
ATOM   8564  C  CG  . PRO C 1 384 ? 296.436 260.535 235.036 1.00 21.52  ? 384 PRO C CG  1 
ATOM   8565  C  CD  . PRO C 1 384 ? 295.260 261.494 235.058 1.00 25.72  ? 384 PRO C CD  1 
ATOM   8566  N  N   . ASN C 1 385 ? 298.087 261.205 238.503 1.00 27.22  ? 385 ASN C N   1 
ATOM   8567  C  CA  . ASN C 1 385 ? 299.300 261.837 238.986 1.00 25.15  ? 385 ASN C CA  1 
ATOM   8568  C  C   . ASN C 1 385 ? 300.283 262.065 237.842 1.00 29.06  ? 385 ASN C C   1 
ATOM   8569  O  O   . ASN C 1 385 ? 300.096 261.594 236.717 1.00 30.47  ? 385 ASN C O   1 
ATOM   8570  C  CB  . ASN C 1 385 ? 299.958 260.967 240.054 1.00 26.15  ? 385 ASN C CB  1 
ATOM   8571  C  CG  . ASN C 1 385 ? 299.960 261.614 241.408 1.00 30.62  ? 385 ASN C CG  1 
ATOM   8572  O  OD1 . ASN C 1 385 ? 299.454 262.721 241.579 1.00 35.40  ? 385 ASN C OD1 1 
ATOM   8573  N  ND2 . ASN C 1 385 ? 300.537 260.929 242.387 1.00 25.29  ? 385 ASN C ND2 1 
ATOM   8574  N  N   . ASP C 1 386 ? 301.353 262.799 238.147 1.00 27.35  ? 386 ASP C N   1 
ATOM   8575  C  CA  . ASP C 1 386 ? 302.493 262.829 237.240 1.00 29.84  ? 386 ASP C CA  1 
ATOM   8576  C  C   . ASP C 1 386 ? 303.130 261.451 237.125 1.00 30.12  ? 386 ASP C C   1 
ATOM   8577  O  O   . ASP C 1 386 ? 303.686 261.107 236.077 1.00 36.09  ? 386 ASP C O   1 
ATOM   8578  C  CB  . ASP C 1 386 ? 303.517 263.858 237.714 1.00 33.65  ? 386 ASP C CB  1 
ATOM   8579  C  CG  . ASP C 1 386 ? 303.078 265.281 237.441 1.00 42.53  ? 386 ASP C CG  1 
ATOM   8580  O  OD1 . ASP C 1 386 ? 301.996 265.466 236.847 1.00 48.70  ? 386 ASP C OD1 1 
ATOM   8581  O  OD2 . ASP C 1 386 ? 303.812 266.216 237.825 1.00 46.38  ? 386 ASP C OD2 1 
ATOM   8582  N  N   . PHE C 1 387 ? 303.056 260.652 238.191 1.00 27.42  ? 387 PHE C N   1 
ATOM   8583  C  CA  . PHE C 1 387 ? 303.495 259.265 238.140 1.00 23.72  ? 387 PHE C CA  1 
ATOM   8584  C  C   . PHE C 1 387 ? 302.511 258.375 237.395 1.00 23.85  ? 387 PHE C C   1 
ATOM   8585  O  O   . PHE C 1 387 ? 302.886 257.279 236.969 1.00 29.85  ? 387 PHE C O   1 
ATOM   8586  C  CB  . PHE C 1 387 ? 303.700 258.723 239.557 1.00 21.59  ? 387 PHE C CB  1 
ATOM   8587  C  CG  . PHE C 1 387 ? 304.950 259.222 240.228 1.00 19.32  ? 387 PHE C CG  1 
ATOM   8588  C  CD1 . PHE C 1 387 ? 305.892 259.943 239.519 1.00 18.82  ? 387 PHE C CD1 1 
ATOM   8589  C  CD2 . PHE C 1 387 ? 305.180 258.966 241.568 1.00 17.96  ? 387 PHE C CD2 1 
ATOM   8590  C  CE1 . PHE C 1 387 ? 307.040 260.402 240.135 1.00 19.03  ? 387 PHE C CE1 1 
ATOM   8591  C  CE2 . PHE C 1 387 ? 306.327 259.419 242.188 1.00 16.79  ? 387 PHE C CE2 1 
ATOM   8592  C  CZ  . PHE C 1 387 ? 307.257 260.139 241.471 1.00 15.02  ? 387 PHE C CZ  1 
ATOM   8593  N  N   . GLY C 1 388 ? 301.272 258.821 237.224 1.00 23.25  ? 388 GLY C N   1 
ATOM   8594  C  CA  . GLY C 1 388 ? 300.252 258.029 236.576 1.00 20.08  ? 388 GLY C CA  1 
ATOM   8595  C  C   . GLY C 1 388 ? 299.283 257.329 237.501 1.00 23.34  ? 388 GLY C C   1 
ATOM   8596  O  O   . GLY C 1 388 ? 298.620 256.381 237.066 1.00 24.19  ? 388 GLY C O   1 
ATOM   8597  N  N   . LEU C 1 389 ? 299.176 257.761 238.754 1.00 22.42  ? 389 LEU C N   1 
ATOM   8598  C  CA  . LEU C 1 389 ? 298.317 257.122 239.739 1.00 19.60  ? 389 LEU C CA  1 
ATOM   8599  C  C   . LEU C 1 389 ? 297.001 257.876 239.871 1.00 21.05  ? 389 LEU C C   1 
ATOM   8600  O  O   . LEU C 1 389 ? 296.973 259.109 239.845 1.00 23.93  ? 389 LEU C O   1 
ATOM   8601  C  CB  . LEU C 1 389 ? 299.012 257.047 241.099 1.00 20.48  ? 389 LEU C CB  1 
ATOM   8602  C  CG  . LEU C 1 389 ? 300.321 256.257 241.126 1.00 18.98  ? 389 LEU C CG  1 
ATOM   8603  C  CD1 . LEU C 1 389 ? 301.158 256.633 242.335 1.00 13.57  ? 389 LEU C CD1 1 
ATOM   8604  C  CD2 . LEU C 1 389 ? 300.036 254.765 241.108 1.00 18.16  ? 389 LEU C CD2 1 
ATOM   8605  N  N   . TYR C 1 390 ? 295.914 257.127 240.020 1.00 22.65  ? 390 TYR C N   1 
ATOM   8606  C  CA  . TYR C 1 390 ? 294.582 257.689 240.170 1.00 18.44  ? 390 TYR C CA  1 
ATOM   8607  C  C   . TYR C 1 390 ? 294.100 257.560 241.608 1.00 18.98  ? 390 TYR C C   1 
ATOM   8608  O  O   . TYR C 1 390 ? 294.403 256.586 242.300 1.00 23.05  ? 390 TYR C O   1 
ATOM   8609  C  CB  . TYR C 1 390 ? 293.578 256.996 239.245 1.00 21.06  ? 390 TYR C CB  1 
ATOM   8610  C  CG  . TYR C 1 390 ? 293.836 257.197 237.774 1.00 22.68  ? 390 TYR C CG  1 
ATOM   8611  C  CD1 . TYR C 1 390 ? 294.704 256.367 237.084 1.00 22.09  ? 390 TYR C CD1 1 
ATOM   8612  C  CD2 . TYR C 1 390 ? 293.197 258.208 237.071 1.00 20.89  ? 390 TYR C CD2 1 
ATOM   8613  C  CE1 . TYR C 1 390 ? 294.938 256.543 235.738 1.00 24.17  ? 390 TYR C CE1 1 
ATOM   8614  C  CE2 . TYR C 1 390 ? 293.422 258.390 235.724 1.00 21.58  ? 390 TYR C CE2 1 
ATOM   8615  C  CZ  . TYR C 1 390 ? 294.295 257.555 235.063 1.00 23.65  ? 390 TYR C CZ  1 
ATOM   8616  O  OH  . TYR C 1 390 ? 294.526 257.732 233.720 1.00 27.34  ? 390 TYR C OH  1 
ATOM   8617  N  N   . ASP C 1 391 ? 293.343 258.564 242.048 1.00 18.58  ? 391 ASP C N   1 
ATOM   8618  C  CA  . ASP C 1 391 ? 292.572 258.500 243.289 1.00 17.73  ? 391 ASP C CA  1 
ATOM   8619  C  C   . ASP C 1 391 ? 293.454 258.350 244.524 1.00 19.57  ? 391 ASP C C   1 
ATOM   8620  O  O   . ASP C 1 391 ? 293.043 257.750 245.517 1.00 23.96  ? 391 ASP C O   1 
ATOM   8621  C  CB  . ASP C 1 391 ? 291.542 257.367 243.240 1.00 19.31  ? 391 ASP C CB  1 
ATOM   8622  C  CG  . ASP C 1 391 ? 290.401 257.658 242.290 1.00 28.31  ? 391 ASP C CG  1 
ATOM   8623  O  OD1 . ASP C 1 391 ? 289.657 258.631 242.533 1.00 38.11  ? 391 ASP C OD1 1 
ATOM   8624  O  OD2 . ASP C 1 391 ? 290.251 256.917 241.297 1.00 35.33  ? 391 ASP C OD2 1 
ATOM   8625  N  N   . MET C 1 392 ? 294.670 258.897 244.491 1.00 20.50  ? 392 MET C N   1 
ATOM   8626  C  CA  . MET C 1 392 ? 295.479 258.896 245.703 1.00 17.80  ? 392 MET C CA  1 
ATOM   8627  C  C   . MET C 1 392 ? 294.954 259.885 246.733 1.00 19.88  ? 392 MET C C   1 
ATOM   8628  O  O   . MET C 1 392 ? 295.351 259.816 247.900 1.00 24.39  ? 392 MET C O   1 
ATOM   8629  C  CB  . MET C 1 392 ? 296.944 259.184 245.372 1.00 19.65  ? 392 MET C CB  1 
ATOM   8630  C  CG  . MET C 1 392 ? 297.533 258.242 244.332 1.00 21.83  ? 392 MET C CG  1 
ATOM   8631  S  SD  . MET C 1 392 ? 298.196 256.720 245.046 1.00 29.68  ? 392 MET C SD  1 
ATOM   8632  C  CE  . MET C 1 392 ? 299.516 257.346 246.074 1.00 19.45  ? 392 MET C CE  1 
ATOM   8633  N  N   . ALA C 1 393 ? 294.073 260.796 246.327 1.00 21.23  ? 393 ALA C N   1 
ATOM   8634  C  CA  . ALA C 1 393 ? 293.326 261.647 247.242 1.00 15.22  ? 393 ALA C CA  1 
ATOM   8635  C  C   . ALA C 1 393 ? 291.839 261.405 247.032 1.00 21.04  ? 393 ALA C C   1 
ATOM   8636  O  O   . ALA C 1 393 ? 291.349 261.475 245.900 1.00 21.74  ? 393 ALA C O   1 
ATOM   8637  C  CB  . ALA C 1 393 ? 293.662 263.125 247.030 1.00 15.71  ? 393 ALA C CB  1 
ATOM   8638  N  N   . GLY C 1 394 ? 291.128 261.114 248.116 1.00 20.00  ? 394 GLY C N   1 
ATOM   8639  C  CA  . GLY C 1 394 ? 289.701 260.886 248.044 1.00 17.80  ? 394 GLY C CA  1 
ATOM   8640  C  C   . GLY C 1 394 ? 289.332 259.495 247.561 1.00 20.13  ? 394 GLY C C   1 
ATOM   8641  O  O   . GLY C 1 394 ? 290.153 258.577 247.489 1.00 21.57  ? 394 GLY C O   1 
ATOM   8642  N  N   . ASN C 1 395 ? 288.053 259.355 247.213 1.00 18.33  ? 395 ASN C N   1 
ATOM   8643  C  CA  . ASN C 1 395 ? 287.456 258.063 246.891 1.00 17.45  ? 395 ASN C CA  1 
ATOM   8644  C  C   . ASN C 1 395 ? 287.456 257.167 248.122 1.00 18.04  ? 395 ASN C C   1 
ATOM   8645  O  O   . ASN C 1 395 ? 286.556 257.268 248.961 1.00 22.93  ? 395 ASN C O   1 
ATOM   8646  C  CB  . ASN C 1 395 ? 288.183 257.392 245.725 1.00 19.13  ? 395 ASN C CB  1 
ATOM   8647  C  CG  . ASN C 1 395 ? 287.227 256.888 244.662 1.00 20.45  ? 395 ASN C CG  1 
ATOM   8648  O  OD1 . ASN C 1 395 ? 286.071 257.302 244.610 1.00 21.11  ? 395 ASN C OD1 1 
ATOM   8649  N  ND2 . ASN C 1 395 ? 287.702 255.989 243.810 1.00 19.94  ? 395 ASN C ND2 1 
ATOM   8650  N  N   . VAL C 1 396 ? 288.443 256.284 248.243 1.00 19.38  ? 396 VAL C N   1 
ATOM   8651  C  CA  . VAL C 1 396 ? 288.602 255.443 249.423 1.00 16.61  ? 396 VAL C CA  1 
ATOM   8652  C  C   . VAL C 1 396 ? 290.003 255.639 249.984 1.00 17.40  ? 396 VAL C C   1 
ATOM   8653  O  O   . VAL C 1 396 ? 290.976 255.741 249.229 1.00 20.88  ? 396 VAL C O   1 
ATOM   8654  C  CB  . VAL C 1 396 ? 288.346 253.951 249.115 1.00 17.82  ? 396 VAL C CB  1 
ATOM   8655  C  CG1 . VAL C 1 396 ? 286.882 253.723 248.778 1.00 17.96  ? 396 VAL C CG1 1 
ATOM   8656  C  CG2 . VAL C 1 396 ? 289.253 253.464 247.996 1.00 16.99  ? 396 VAL C CG2 1 
ATOM   8657  N  N   . ALA C 1 397 ? 290.101 255.697 251.309 1.00 17.98  ? 397 ALA C N   1 
ATOM   8658  C  CA  . ALA C 1 397 ? 291.395 255.722 251.969 1.00 16.17  ? 397 ALA C CA  1 
ATOM   8659  C  C   . ALA C 1 397 ? 291.999 254.324 251.960 1.00 17.08  ? 397 ALA C C   1 
ATOM   8660  O  O   . ALA C 1 397 ? 291.285 253.319 251.966 1.00 20.27  ? 397 ALA C O   1 
ATOM   8661  C  CB  . ALA C 1 397 ? 291.263 256.237 253.401 1.00 14.02  ? 397 ALA C CB  1 
ATOM   8662  N  N   . GLU C 1 398 ? 293.325 254.260 251.948 1.00 17.55  ? 398 GLU C N   1 
ATOM   8663  C  CA  . GLU C 1 398 ? 294.028 253.033 251.605 1.00 16.01  ? 398 GLU C CA  1 
ATOM   8664  C  C   . GLU C 1 398 ? 294.865 252.523 252.770 1.00 16.36  ? 398 GLU C C   1 
ATOM   8665  O  O   . GLU C 1 398 ? 295.538 253.298 253.455 1.00 24.40  ? 398 GLU C O   1 
ATOM   8666  C  CB  . GLU C 1 398 ? 294.908 253.255 250.374 1.00 19.79  ? 398 GLU C CB  1 
ATOM   8667  C  CG  . GLU C 1 398 ? 294.105 253.595 249.129 1.00 18.73  ? 398 GLU C CG  1 
ATOM   8668  C  CD  . GLU C 1 398 ? 294.856 254.479 248.161 1.00 19.74  ? 398 GLU C CD  1 
ATOM   8669  O  OE1 . GLU C 1 398 ? 296.044 254.209 247.907 1.00 23.29  ? 398 GLU C OE1 1 
ATOM   8670  O  OE2 . GLU C 1 398 ? 294.257 255.450 247.657 1.00 20.92  ? 398 GLU C OE2 1 
ATOM   8671  N  N   . TRP C 1 399 ? 294.809 251.211 252.984 1.00 16.98  ? 399 TRP C N   1 
ATOM   8672  C  CA  . TRP C 1 399 ? 295.645 250.559 253.983 1.00 15.54  ? 399 TRP C CA  1 
ATOM   8673  C  C   . TRP C 1 399 ? 297.120 250.664 253.617 1.00 14.82  ? 399 TRP C C   1 
ATOM   8674  O  O   . TRP C 1 399 ? 297.493 250.591 252.443 1.00 19.82  ? 399 TRP C O   1 
ATOM   8675  C  CB  . TRP C 1 399 ? 295.273 249.082 254.108 1.00 14.72  ? 399 TRP C CB  1 
ATOM   8676  C  CG  . TRP C 1 399 ? 294.002 248.785 254.834 1.00 14.59  ? 399 TRP C CG  1 
ATOM   8677  C  CD1 . TRP C 1 399 ? 292.874 248.229 254.311 1.00 13.80  ? 399 TRP C CD1 1 
ATOM   8678  C  CD2 . TRP C 1 399 ? 293.745 248.977 256.229 1.00 14.84  ? 399 TRP C CD2 1 
ATOM   8679  N  NE1 . TRP C 1 399 ? 291.922 248.082 255.288 1.00 13.07  ? 399 TRP C NE1 1 
ATOM   8680  C  CE2 . TRP C 1 399 ? 292.433 248.533 256.476 1.00 14.67  ? 399 TRP C CE2 1 
ATOM   8681  C  CE3 . TRP C 1 399 ? 294.495 249.489 257.292 1.00 15.08  ? 399 TRP C CE3 1 
ATOM   8682  C  CZ2 . TRP C 1 399 ? 291.854 248.587 257.739 1.00 13.78  ? 399 TRP C CZ2 1 
ATOM   8683  C  CZ3 . TRP C 1 399 ? 293.919 249.540 258.543 1.00 14.65  ? 399 TRP C CZ3 1 
ATOM   8684  C  CH2 . TRP C 1 399 ? 292.612 249.093 258.757 1.00 15.26  ? 399 TRP C CH2 1 
ATOM   8685  N  N   . THR C 1 400 ? 297.959 250.830 254.633 1.00 15.78  ? 400 THR C N   1 
ATOM   8686  C  CA  . THR C 1 400 ? 299.398 250.657 254.508 1.00 17.50  ? 400 THR C CA  1 
ATOM   8687  C  C   . THR C 1 400 ? 299.845 249.549 255.454 1.00 19.20  ? 400 THR C C   1 
ATOM   8688  O  O   . THR C 1 400 ? 299.113 249.135 256.355 1.00 21.51  ? 400 THR C O   1 
ATOM   8689  C  CB  . THR C 1 400 ? 300.157 251.962 254.802 1.00 18.83  ? 400 THR C CB  1 
ATOM   8690  O  OG1 . THR C 1 400 ? 300.329 252.119 256.215 1.00 25.94  ? 400 THR C OG1 1 
ATOM   8691  C  CG2 . THR C 1 400 ? 299.404 253.161 254.251 1.00 15.95  ? 400 THR C CG2 1 
ATOM   8692  N  N   . SER C 1 401 ? 301.063 249.061 255.239 1.00 19.49  ? 401 SER C N   1 
ATOM   8693  C  CA  . SER C 1 401 ? 301.610 247.996 256.070 1.00 18.39  ? 401 SER C CA  1 
ATOM   8694  C  C   . SER C 1 401 ? 302.224 248.507 257.365 1.00 20.63  ? 401 SER C C   1 
ATOM   8695  O  O   . SER C 1 401 ? 302.640 247.695 258.198 1.00 22.27  ? 401 SER C O   1 
ATOM   8696  C  CB  . SER C 1 401 ? 302.658 247.207 255.285 1.00 18.14  ? 401 SER C CB  1 
ATOM   8697  O  OG  . SER C 1 401 ? 303.758 248.031 254.946 1.00 23.66  ? 401 SER C OG  1 
ATOM   8698  N  N   . THR C 1 402 ? 302.279 249.820 257.560 1.00 19.55  ? 402 THR C N   1 
ATOM   8699  C  CA  . THR C 1 402 ? 302.933 250.394 258.725 1.00 18.82  ? 402 THR C CA  1 
ATOM   8700  C  C   . THR C 1 402 ? 302.021 250.334 259.943 1.00 20.76  ? 402 THR C C   1 
ATOM   8701  O  O   . THR C 1 402 ? 300.836 250.670 259.863 1.00 23.09  ? 402 THR C O   1 
ATOM   8702  C  CB  . THR C 1 402 ? 303.336 251.840 258.443 1.00 22.11  ? 402 THR C CB  1 
ATOM   8703  O  OG1 . THR C 1 402 ? 304.178 251.886 257.285 1.00 26.14  ? 402 THR C OG1 1 
ATOM   8704  C  CG2 . THR C 1 402 ? 304.077 252.430 259.628 1.00 17.84  ? 402 THR C CG2 1 
ATOM   8705  N  N   . ALA C 1 403 ? 302.576 249.897 261.070 1.00 23.37  ? 403 ALA C N   1 
ATOM   8706  C  CA  . ALA C 1 403 ? 301.868 250.000 262.336 1.00 20.56  ? 403 ALA C CA  1 
ATOM   8707  C  C   . ALA C 1 403 ? 301.816 251.456 262.773 1.00 23.51  ? 403 ALA C C   1 
ATOM   8708  O  O   . ALA C 1 403 ? 302.755 252.222 262.546 1.00 29.49  ? 403 ALA C O   1 
ATOM   8709  C  CB  . ALA C 1 403 ? 302.551 249.148 263.404 1.00 17.08  ? 403 ALA C CB  1 
ATOM   8710  N  N   . PHE C 1 404 ? 300.712 251.841 263.403 1.00 24.71  ? 404 PHE C N   1 
ATOM   8711  C  CA  . PHE C 1 404 ? 300.492 253.234 263.756 1.00 24.60  ? 404 PHE C CA  1 
ATOM   8712  C  C   . PHE C 1 404 ? 301.164 253.567 265.082 1.00 27.48  ? 404 PHE C C   1 
ATOM   8713  O  O   . PHE C 1 404 ? 301.015 252.836 266.066 1.00 32.43  ? 404 PHE C O   1 
ATOM   8714  C  CB  . PHE C 1 404 ? 299.000 253.553 263.835 1.00 21.81  ? 404 PHE C CB  1 
ATOM   8715  C  CG  . PHE C 1 404 ? 298.717 254.940 264.319 1.00 27.53  ? 404 PHE C CG  1 
ATOM   8716  C  CD1 . PHE C 1 404 ? 298.805 256.018 263.456 1.00 25.61  ? 404 PHE C CD1 1 
ATOM   8717  C  CD2 . PHE C 1 404 ? 298.386 255.171 265.641 1.00 29.56  ? 404 PHE C CD2 1 
ATOM   8718  C  CE1 . PHE C 1 404 ? 298.556 257.297 263.902 1.00 27.98  ? 404 PHE C CE1 1 
ATOM   8719  C  CE2 . PHE C 1 404 ? 298.137 256.447 266.090 1.00 27.10  ? 404 PHE C CE2 1 
ATOM   8720  C  CZ  . PHE C 1 404 ? 298.222 257.511 265.221 1.00 27.36  ? 404 PHE C CZ  1 
ATOM   8721  N  N   . SER C 1 405 ? 301.906 254.671 265.095 1.00 28.93  ? 405 SER C N   1 
ATOM   8722  C  CA  . SER C 1 405 ? 302.489 255.228 266.305 1.00 26.71  ? 405 SER C CA  1 
ATOM   8723  C  C   . SER C 1 405 ? 302.480 256.743 266.183 1.00 30.01  ? 405 SER C C   1 
ATOM   8724  O  O   . SER C 1 405 ? 302.691 257.284 265.095 1.00 36.00  ? 405 SER C O   1 
ATOM   8725  C  CB  . SER C 1 405 ? 303.918 254.721 266.535 1.00 32.35  ? 405 SER C CB  1 
ATOM   8726  O  OG  . SER C 1 405 ? 304.436 255.197 267.765 1.00 36.92  ? 405 SER C OG  1 
ATOM   8727  N  N   . GLU C 1 406 ? 302.226 257.424 267.299 1.00 32.51  ? 406 GLU C N   1 
ATOM   8728  C  CA  . GLU C 1 406 ? 302.164 258.881 267.265 1.00 35.42  ? 406 GLU C CA  1 
ATOM   8729  C  C   . GLU C 1 406 ? 303.519 259.475 266.902 1.00 34.97  ? 406 GLU C C   1 
ATOM   8730  O  O   . GLU C 1 406 ? 303.601 260.476 266.181 1.00 37.86  ? 406 GLU C O   1 
ATOM   8731  C  CB  . GLU C 1 406 ? 301.673 259.416 268.609 1.00 42.68  ? 406 GLU C CB  1 
ATOM   8732  C  CG  . GLU C 1 406 ? 300.162 259.404 268.746 1.00 44.65  ? 406 GLU C CG  1 
ATOM   8733  C  CD  . GLU C 1 406 ? 299.530 260.702 268.290 1.00 56.39  ? 406 GLU C CD  1 
ATOM   8734  O  OE1 . GLU C 1 406 ? 298.499 260.648 267.587 1.00 55.18  ? 406 GLU C OE1 1 
ATOM   8735  O  OE2 . GLU C 1 406 ? 300.064 261.777 268.634 1.00 61.64  ? 406 GLU C OE2 1 
ATOM   8736  N  N   . SER C 1 407 ? 304.594 258.871 267.395 1.00 35.86  ? 407 SER C N   1 
ATOM   8737  C  CA  . SER C 1 407 ? 305.953 259.300 267.067 1.00 33.02  ? 407 SER C CA  1 
ATOM   8738  C  C   . SER C 1 407 ? 306.594 258.372 266.040 1.00 31.67  ? 407 SER C C   1 
ATOM   8739  O  O   . SER C 1 407 ? 307.808 258.185 266.011 1.00 34.07  ? 407 SER C O   1 
ATOM   8740  C  CB  . SER C 1 407 ? 306.789 259.377 268.338 1.00 36.69  ? 407 SER C CB  1 
ATOM   8741  O  OG  . SER C 1 407 ? 306.723 258.163 269.063 1.00 36.37  ? 407 SER C OG  1 
ATOM   8742  N  N   . GLY C 1 408 ? 305.762 257.782 265.178 1.00 35.24  ? 408 GLY C N   1 
ATOM   8743  C  CA  . GLY C 1 408 ? 306.261 256.821 264.211 1.00 30.92  ? 408 GLY C CA  1 
ATOM   8744  C  C   . GLY C 1 408 ? 307.218 257.401 263.195 1.00 30.10  ? 408 GLY C C   1 
ATOM   8745  O  O   . GLY C 1 408 ? 308.135 256.709 262.743 1.00 32.02  ? 408 GLY C O   1 
ATOM   8746  N  N   . LEU C 1 409 ? 307.030 258.668 262.818 1.00 29.15  ? 409 LEU C N   1 
ATOM   8747  C  CA  . LEU C 1 409 ? 307.929 259.285 261.850 1.00 30.29  ? 409 LEU C CA  1 
ATOM   8748  C  C   . LEU C 1 409 ? 309.343 259.419 262.400 1.00 30.36  ? 409 LEU C C   1 
ATOM   8749  O  O   . LEU C 1 409 ? 310.312 259.332 261.638 1.00 34.63  ? 409 LEU C O   1 
ATOM   8750  C  CB  . LEU C 1 409 ? 307.391 260.652 261.430 1.00 34.34  ? 409 LEU C CB  1 
ATOM   8751  C  CG  . LEU C 1 409 ? 306.749 260.730 260.043 1.00 36.95  ? 409 LEU C CG  1 
ATOM   8752  C  CD1 . LEU C 1 409 ? 305.544 259.806 259.957 1.00 25.70  ? 409 LEU C CD1 1 
ATOM   8753  C  CD2 . LEU C 1 409 ? 306.360 262.161 259.711 1.00 37.44  ? 409 LEU C CD2 1 
ATOM   8754  N  N   . LYS C 1 410 ? 309.481 259.640 263.709 1.00 33.67  ? 410 LYS C N   1 
ATOM   8755  C  CA  . LYS C 1 410 ? 310.802 259.745 264.317 1.00 31.46  ? 410 LYS C CA  1 
ATOM   8756  C  C   . LYS C 1 410 ? 311.442 258.383 264.544 1.00 30.85  ? 410 LYS C C   1 
ATOM   8757  O  O   . LYS C 1 410 ? 312.670 258.289 264.632 1.00 36.07  ? 410 LYS C O   1 
ATOM   8758  C  CB  . LYS C 1 410 ? 310.711 260.496 265.646 1.00 32.65  ? 410 LYS C CB  1 
ATOM   8759  C  CG  . LYS C 1 410 ? 310.606 262.002 265.510 1.00 39.28  ? 410 LYS C CG  1 
ATOM   8760  C  CD  . LYS C 1 410 ? 311.889 262.685 265.955 1.00 38.50  ? 410 LYS C CD  1 
ATOM   8761  C  CE  . LYS C 1 410 ? 311.901 264.149 265.550 1.00 44.40  ? 410 LYS C CE  1 
ATOM   8762  N  NZ  . LYS C 1 410 ? 311.898 265.052 266.732 1.00 46.25  ? 410 LYS C NZ  1 
ATOM   8763  N  N   . GLN C 1 411 ? 310.640 257.326 264.637 1.00 29.00  ? 411 GLN C N   1 
ATOM   8764  C  CA  . GLN C 1 411 ? 311.144 256.005 264.983 1.00 28.92  ? 411 GLN C CA  1 
ATOM   8765  C  C   . GLN C 1 411 ? 311.508 255.159 263.771 1.00 29.73  ? 411 GLN C C   1 
ATOM   8766  O  O   . GLN C 1 411 ? 312.193 254.144 263.931 1.00 33.30  ? 411 GLN C O   1 
ATOM   8767  C  CB  . GLN C 1 411 ? 310.113 255.261 265.833 1.00 30.09  ? 411 GLN C CB  1 
ATOM   8768  C  CG  . GLN C 1 411 ? 309.864 255.903 267.181 1.00 30.36  ? 411 GLN C CG  1 
ATOM   8769  C  CD  . GLN C 1 411 ? 308.624 255.367 267.854 1.00 38.51  ? 411 GLN C CD  1 
ATOM   8770  O  OE1 . GLN C 1 411 ? 307.625 255.077 267.198 1.00 40.86  ? 411 GLN C OE1 1 
ATOM   8771  N  NE2 . GLN C 1 411 ? 308.677 255.236 269.173 1.00 40.24  ? 411 GLN C NE2 1 
ATOM   8772  N  N   . MET C 1 412 ? 311.074 255.541 262.576 1.00 32.04  ? 412 MET C N   1 
ATOM   8773  C  CA  . MET C 1 412 ? 311.440 254.803 261.381 1.00 27.09  ? 412 MET C CA  1 
ATOM   8774  C  C   . MET C 1 412 ? 312.847 255.185 260.926 1.00 27.78  ? 412 MET C C   1 
ATOM   8775  O  O   . MET C 1 412 ? 313.478 256.102 261.457 1.00 30.46  ? 412 MET C O   1 
ATOM   8776  C  CB  . MET C 1 412 ? 310.426 255.049 260.267 1.00 23.56  ? 412 MET C CB  1 
ATOM   8777  C  CG  . MET C 1 412 ? 309.142 254.260 260.431 1.00 27.40  ? 412 MET C CG  1 
ATOM   8778  S  SD  . MET C 1 412 ? 307.816 254.793 259.335 1.00 40.51  ? 412 MET C SD  1 
ATOM   8779  C  CE  . MET C 1 412 ? 308.413 256.402 258.828 1.00 30.99  ? 412 MET C CE  1 
ATOM   8780  N  N   . SER C 1 413 ? 313.342 254.455 259.931 1.00 28.17  ? 413 SER C N   1 
ATOM   8781  C  CA  . SER C 1 413 ? 314.674 254.682 259.397 1.00 24.82  ? 413 SER C CA  1 
ATOM   8782  C  C   . SER C 1 413 ? 314.656 255.786 258.340 1.00 27.03  ? 413 SER C C   1 
ATOM   8783  O  O   . SER C 1 413 ? 313.605 256.278 257.922 1.00 27.13  ? 413 SER C O   1 
ATOM   8784  C  CB  . SER C 1 413 ? 315.238 253.392 258.806 1.00 26.20  ? 413 SER C CB  1 
ATOM   8785  O  OG  . SER C 1 413 ? 316.641 253.473 258.635 1.00 26.99  ? 413 SER C OG  1 
ATOM   8786  N  N   . ASP C 1 414 ? 315.858 256.178 257.915 1.00 34.57  ? 414 ASP C N   1 
ATOM   8787  C  CA  . ASP C 1 414 ? 316.014 257.152 256.839 1.00 33.15  ? 414 ASP C CA  1 
ATOM   8788  C  C   . ASP C 1 414 ? 315.768 256.531 255.471 1.00 26.34  ? 414 ASP C C   1 
ATOM   8789  O  O   . ASP C 1 414 ? 315.209 257.183 254.582 1.00 24.07  ? 414 ASP C O   1 
ATOM   8790  C  CB  . ASP C 1 414 ? 317.415 257.762 256.892 1.00 32.04  ? 414 ASP C CB  1 
ATOM   8791  C  CG  . ASP C 1 414 ? 317.404 259.199 257.340 1.00 42.04  ? 414 ASP C CG  1 
ATOM   8792  O  OD1 . ASP C 1 414 ? 318.480 259.830 257.336 1.00 49.72  ? 414 ASP C OD1 1 
ATOM   8793  O  OD2 . ASP C 1 414 ? 316.315 259.703 257.677 1.00 48.47  ? 414 ASP C OD2 1 
ATOM   8794  N  N   . ILE C 1 415 ? 316.184 255.284 255.281 1.00 23.01  ? 415 ILE C N   1 
ATOM   8795  C  CA  . ILE C 1 415 ? 316.088 254.596 254.001 1.00 25.00  ? 415 ILE C CA  1 
ATOM   8796  C  C   . ILE C 1 415 ? 315.013 253.527 254.108 1.00 26.78  ? 415 ILE C C   1 
ATOM   8797  O  O   . ILE C 1 415 ? 314.987 252.759 255.078 1.00 28.07  ? 415 ILE C O   1 
ATOM   8798  C  CB  . ILE C 1 415 ? 317.439 253.986 253.587 1.00 30.95  ? 415 ILE C CB  1 
ATOM   8799  C  CG1 . ILE C 1 415 ? 317.293 253.206 252.280 1.00 29.84  ? 415 ILE C CG1 1 
ATOM   8800  C  CG2 . ILE C 1 415 ? 317.998 253.111 254.697 1.00 24.57  ? 415 ILE C CG2 1 
ATOM   8801  C  CD1 . ILE C 1 415 ? 318.515 252.400 251.908 1.00 29.98  ? 415 ILE C CD1 1 
ATOM   8802  N  N   . ASN C 1 416 ? 314.125 253.485 253.118 1.00 24.78  ? 416 ASN C N   1 
ATOM   8803  C  CA  . ASN C 1 416 ? 313.020 252.536 253.075 1.00 18.65  ? 416 ASN C CA  1 
ATOM   8804  C  C   . ASN C 1 416 ? 312.306 252.456 254.429 1.00 21.87  ? 416 ASN C C   1 
ATOM   8805  O  O   . ASN C 1 416 ? 312.169 251.372 255.000 1.00 25.81  ? 416 ASN C O   1 
ATOM   8806  C  CB  . ASN C 1 416 ? 313.505 251.158 252.650 1.00 23.65  ? 416 ASN C CB  1 
ATOM   8807  C  CG  . ASN C 1 416 ? 313.993 251.130 251.218 1.00 20.41  ? 416 ASN C CG  1 
ATOM   8808  O  OD1 . ASN C 1 416 ? 313.628 251.979 250.407 1.00 25.38  ? 416 ASN C OD1 1 
ATOM   8809  N  ND2 . ASN C 1 416 ? 314.823 250.147 250.899 1.00 21.32  ? 416 ASN C ND2 1 
ATOM   8810  N  N   . PRO C 1 417 ? 311.843 253.585 254.961 1.00 24.42  ? 417 PRO C N   1 
ATOM   8811  C  CA  . PRO C 1 417 ? 311.284 253.582 256.318 1.00 22.43  ? 417 PRO C CA  1 
ATOM   8812  C  C   . PRO C 1 417 ? 310.113 252.620 256.446 1.00 21.49  ? 417 PRO C C   1 
ATOM   8813  O  O   . PRO C 1 417 ? 309.277 252.500 255.548 1.00 27.61  ? 417 PRO C O   1 
ATOM   8814  C  CB  . PRO C 1 417 ? 310.842 255.035 256.524 1.00 19.38  ? 417 PRO C CB  1 
ATOM   8815  C  CG  . PRO C 1 417 ? 311.598 255.821 255.512 1.00 19.30  ? 417 PRO C CG  1 
ATOM   8816  C  CD  . PRO C 1 417 ? 311.808 254.920 254.344 1.00 19.93  ? 417 PRO C CD  1 
ATOM   8817  N  N   . GLU C 1 418 ? 310.060 251.932 257.583 1.00 21.61  ? 418 GLU C N   1 
ATOM   8818  C  CA  . GLU C 1 418 ? 308.982 250.997 257.862 1.00 22.19  ? 418 GLU C CA  1 
ATOM   8819  C  C   . GLU C 1 418 ? 308.890 250.784 259.364 1.00 21.23  ? 418 GLU C C   1 
ATOM   8820  O  O   . GLU C 1 418 ? 309.911 250.730 260.053 1.00 23.89  ? 418 GLU C O   1 
ATOM   8821  C  CB  . GLU C 1 418 ? 309.206 249.661 257.141 1.00 20.51  ? 418 GLU C CB  1 
ATOM   8822  C  CG  . GLU C 1 418 ? 308.164 248.577 257.423 1.00 26.37  ? 418 GLU C CG  1 
ATOM   8823  C  CD  . GLU C 1 418 ? 306.721 249.053 257.307 1.00 27.98  ? 418 GLU C CD  1 
ATOM   8824  O  OE1 . GLU C 1 418 ? 306.480 250.268 257.168 1.00 29.01  ? 418 GLU C OE1 1 
ATOM   8825  O  OE2 . GLU C 1 418 ? 305.817 248.193 257.352 1.00 30.94  ? 418 GLU C OE2 1 
ATOM   8826  N  N   . LEU C 1 419 ? 307.663 250.673 259.862 1.00 25.38  ? 419 LEU C N   1 
ATOM   8827  C  CA  . LEU C 1 419 ? 307.387 250.363 261.262 1.00 25.69  ? 419 LEU C CA  1 
ATOM   8828  C  C   . LEU C 1 419 ? 306.483 249.136 261.269 1.00 26.10  ? 419 LEU C C   1 
ATOM   8829  O  O   . LEU C 1 419 ? 305.256 249.251 261.309 1.00 30.48  ? 419 LEU C O   1 
ATOM   8830  C  CB  . LEU C 1 419 ? 306.751 251.545 261.978 1.00 26.75  ? 419 LEU C CB  1 
ATOM   8831  C  CG  . LEU C 1 419 ? 307.082 251.690 263.463 1.00 27.68  ? 419 LEU C CG  1 
ATOM   8832  C  CD1 . LEU C 1 419 ? 308.576 251.872 263.662 1.00 26.80  ? 419 LEU C CD1 1 
ATOM   8833  C  CD2 . LEU C 1 419 ? 306.314 252.849 264.068 1.00 35.47  ? 419 LEU C CD2 1 
ATOM   8834  N  N   . GLU C 1 420 ? 307.097 247.960 261.233 1.00 29.64  ? 420 GLU C N   1 
ATOM   8835  C  CA  . GLU C 1 420 ? 306.380 246.702 261.091 1.00 26.80  ? 420 GLU C CA  1 
ATOM   8836  C  C   . GLU C 1 420 ? 306.152 246.079 262.459 1.00 29.28  ? 420 GLU C C   1 
ATOM   8837  O  O   . GLU C 1 420 ? 307.086 245.964 263.259 1.00 37.69  ? 420 GLU C O   1 
ATOM   8838  C  CB  . GLU C 1 420 ? 307.159 245.738 260.197 1.00 28.38  ? 420 GLU C CB  1 
ATOM   8839  C  CG  . GLU C 1 420 ? 306.333 244.592 259.652 1.00 36.30  ? 420 GLU C CG  1 
ATOM   8840  C  CD  . GLU C 1 420 ? 306.654 243.276 260.326 1.00 42.19  ? 420 GLU C CD  1 
ATOM   8841  O  OE1 . GLU C 1 420 ? 307.812 243.093 260.755 1.00 42.01  ? 420 GLU C OE1 1 
ATOM   8842  O  OE2 . GLU C 1 420 ? 305.748 242.425 260.428 1.00 43.01  ? 420 GLU C OE2 1 
ATOM   8843  N  N   . TYR C 1 421 ? 304.910 245.688 262.727 1.00 28.54  ? 421 TYR C N   1 
ATOM   8844  C  CA  . TYR C 1 421 ? 304.566 245.002 263.963 1.00 25.99  ? 421 TYR C CA  1 
ATOM   8845  C  C   . TYR C 1 421 ? 303.610 243.864 263.654 1.00 24.26  ? 421 TYR C C   1 
ATOM   8846  O  O   . TYR C 1 421 ? 302.576 244.076 263.015 1.00 30.23  ? 421 TYR C O   1 
ATOM   8847  C  CB  . TYR C 1 421 ? 303.933 245.959 264.977 1.00 25.31  ? 421 TYR C CB  1 
ATOM   8848  C  CG  . TYR C 1 421 ? 303.678 245.324 266.322 1.00 27.54  ? 421 TYR C CG  1 
ATOM   8849  C  CD1 . TYR C 1 421 ? 304.717 244.781 267.063 1.00 27.83  ? 421 TYR C CD1 1 
ATOM   8850  C  CD2 . TYR C 1 421 ? 302.396 245.255 266.845 1.00 27.00  ? 421 TYR C CD2 1 
ATOM   8851  C  CE1 . TYR C 1 421 ? 304.488 244.196 268.290 1.00 26.63  ? 421 TYR C CE1 1 
ATOM   8852  C  CE2 . TYR C 1 421 ? 302.158 244.673 268.071 1.00 26.82  ? 421 TYR C CE2 1 
ATOM   8853  C  CZ  . TYR C 1 421 ? 303.207 244.144 268.788 1.00 27.62  ? 421 TYR C CZ  1 
ATOM   8854  O  OH  . TYR C 1 421 ? 302.972 243.563 270.009 1.00 36.38  ? 421 TYR C OH  1 
ATOM   8855  N  N   . LYS C 1 422 ? 303.956 242.663 264.106 1.00 25.02  ? 422 LYS C N   1 
ATOM   8856  C  CA  . LYS C 1 422 ? 303.068 241.504 264.029 1.00 25.22  ? 422 LYS C CA  1 
ATOM   8857  C  C   . LYS C 1 422 ? 302.502 241.292 265.427 1.00 24.07  ? 422 LYS C C   1 
ATOM   8858  O  O   . LYS C 1 422 ? 303.117 240.648 266.277 1.00 28.68  ? 422 LYS C O   1 
ATOM   8859  C  CB  . LYS C 1 422 ? 303.809 240.276 263.517 1.00 25.86  ? 422 LYS C CB  1 
ATOM   8860  C  CG  . LYS C 1 422 ? 304.068 240.291 262.023 1.00 26.64  ? 422 LYS C CG  1 
ATOM   8861  C  CD  . LYS C 1 422 ? 304.847 239.066 261.587 1.00 24.41  ? 422 LYS C CD  1 
ATOM   8862  C  CE  . LYS C 1 422 ? 306.180 239.451 260.978 1.00 31.23  ? 422 LYS C CE  1 
ATOM   8863  N  NZ  . LYS C 1 422 ? 306.118 239.482 259.493 1.00 30.87  ? 422 LYS C NZ  1 
ATOM   8864  N  N   . ALA C 1 423 ? 301.318 241.846 265.665 1.00 27.27  ? 423 ALA C N   1 
ATOM   8865  C  CA  . ALA C 1 423 ? 300.728 241.810 266.995 1.00 29.30  ? 423 ALA C CA  1 
ATOM   8866  C  C   . ALA C 1 423 ? 300.384 240.384 267.404 1.00 32.81  ? 423 ALA C C   1 
ATOM   8867  O  O   . ALA C 1 423 ? 299.974 239.563 266.580 1.00 35.50  ? 423 ALA C O   1 
ATOM   8868  C  CB  . ALA C 1 423 ? 299.475 242.684 267.041 1.00 25.06  ? 423 ALA C CB  1 
ATOM   8869  N  N   . ALA C 1 424 ? 300.562 240.092 268.689 1.00 29.00  ? 424 ALA C N   1 
ATOM   8870  C  CA  . ALA C 1 424 ? 300.130 238.820 269.244 1.00 29.29  ? 424 ALA C CA  1 
ATOM   8871  C  C   . ALA C 1 424 ? 298.618 238.815 269.431 1.00 35.71  ? 424 ALA C C   1 
ATOM   8872  O  O   . ALA C 1 424 ? 297.993 239.858 269.638 1.00 38.53  ? 424 ALA C O   1 
ATOM   8873  C  CB  . ALA C 1 424 ? 300.824 238.549 270.577 1.00 28.97  ? 424 ALA C CB  1 
ATOM   8874  N  N   . LEU C 1 425 ? 298.030 237.620 269.355 1.00 34.97  ? 425 LEU C N   1 
ATOM   8875  C  CA  . LEU C 1 425 ? 296.579 237.511 269.472 1.00 36.49  ? 425 LEU C CA  1 
ATOM   8876  C  C   . LEU C 1 425 ? 296.094 238.021 270.822 1.00 39.93  ? 425 LEU C C   1 
ATOM   8877  O  O   . LEU C 1 425 ? 295.080 238.724 270.901 1.00 41.50  ? 425 LEU C O   1 
ATOM   8878  C  CB  . LEU C 1 425 ? 296.140 236.065 269.254 1.00 38.73  ? 425 LEU C CB  1 
ATOM   8879  C  CG  . LEU C 1 425 ? 295.991 235.647 267.791 1.00 42.62  ? 425 LEU C CG  1 
ATOM   8880  C  CD1 . LEU C 1 425 ? 296.473 234.223 267.582 1.00 41.06  ? 425 LEU C CD1 1 
ATOM   8881  C  CD2 . LEU C 1 425 ? 294.552 235.809 267.334 1.00 45.88  ? 425 LEU C CD2 1 
ATOM   8882  N  N   . THR C 1 426 ? 296.803 237.681 271.894 1.00 40.11  ? 426 THR C N   1 
ATOM   8883  C  CA  . THR C 1 426 ? 296.450 238.144 273.228 1.00 36.46  ? 426 THR C CA  1 
ATOM   8884  C  C   . THR C 1 426 ? 297.012 239.523 273.542 1.00 37.83  ? 426 THR C C   1 
ATOM   8885  O  O   . THR C 1 426 ? 297.011 239.927 274.709 1.00 43.00  ? 426 THR C O   1 
ATOM   8886  C  CB  . THR C 1 426 ? 296.929 237.140 274.277 1.00 41.43  ? 426 THR C CB  1 
ATOM   8887  O  OG1 . THR C 1 426 ? 298.294 236.794 274.018 1.00 49.03  ? 426 THR C OG1 1 
ATOM   8888  C  CG2 . THR C 1 426 ? 296.078 235.884 274.230 1.00 39.05  ? 426 THR C CG2 1 
ATOM   8889  N  N   . ASP C 1 427 ? 297.495 240.246 272.537 1.00 35.99  ? 427 ASP C N   1 
ATOM   8890  C  CA  . ASP C 1 427 ? 297.944 241.609 272.749 1.00 31.10  ? 427 ASP C CA  1 
ATOM   8891  C  C   . ASP C 1 427 ? 296.748 242.527 272.993 1.00 33.39  ? 427 ASP C C   1 
ATOM   8892  O  O   . ASP C 1 427 ? 295.636 242.244 272.540 1.00 38.40  ? 427 ASP C O   1 
ATOM   8893  C  CB  . ASP C 1 427 ? 298.737 242.104 271.544 1.00 31.42  ? 427 ASP C CB  1 
ATOM   8894  C  CG  . ASP C 1 427 ? 300.233 242.005 271.750 1.00 37.29  ? 427 ASP C CG  1 
ATOM   8895  O  OD1 . ASP C 1 427 ? 300.664 241.821 272.906 1.00 43.22  ? 427 ASP C OD1 1 
ATOM   8896  O  OD2 . ASP C 1 427 ? 300.976 242.108 270.754 1.00 36.05  ? 427 ASP C OD2 1 
ATOM   8897  N  N   . PRO C 1 428 ? 296.945 243.626 273.717 1.00 33.42  ? 428 PRO C N   1 
ATOM   8898  C  CA  . PRO C 1 428 ? 295.861 244.601 273.868 1.00 31.90  ? 428 PRO C CA  1 
ATOM   8899  C  C   . PRO C 1 428 ? 295.433 245.148 272.514 1.00 30.34  ? 428 PRO C C   1 
ATOM   8900  O  O   . PRO C 1 428 ? 296.240 245.306 271.597 1.00 30.95  ? 428 PRO C O   1 
ATOM   8901  C  CB  . PRO C 1 428 ? 296.476 245.694 274.752 1.00 28.07  ? 428 PRO C CB  1 
ATOM   8902  C  CG  . PRO C 1 428 ? 297.944 245.414 274.788 1.00 29.26  ? 428 PRO C CG  1 
ATOM   8903  C  CD  . PRO C 1 428 ? 298.112 243.956 274.548 1.00 30.82  ? 428 PRO C CD  1 
ATOM   8904  N  N   . TYR C 1 429 ? 294.135 245.431 272.399 1.00 32.29  ? 429 TYR C N   1 
ATOM   8905  C  CA  . TYR C 1 429 ? 293.584 245.898 271.131 1.00 27.81  ? 429 TYR C CA  1 
ATOM   8906  C  C   . TYR C 1 429 ? 294.276 247.163 270.643 1.00 28.56  ? 429 TYR C C   1 
ATOM   8907  O  O   . TYR C 1 429 ? 294.370 247.391 269.432 1.00 30.68  ? 429 TYR C O   1 
ATOM   8908  C  CB  . TYR C 1 429 ? 292.082 246.138 271.282 1.00 28.62  ? 429 TYR C CB  1 
ATOM   8909  C  CG  . TYR C 1 429 ? 291.310 246.109 269.985 1.00 25.70  ? 429 TYR C CG  1 
ATOM   8910  C  CD1 . TYR C 1 429 ? 291.534 245.119 269.042 1.00 26.99  ? 429 TYR C CD1 1 
ATOM   8911  C  CD2 . TYR C 1 429 ? 290.350 247.071 269.709 1.00 22.69  ? 429 TYR C CD2 1 
ATOM   8912  C  CE1 . TYR C 1 429 ? 290.827 245.090 267.860 1.00 25.43  ? 429 TYR C CE1 1 
ATOM   8913  C  CE2 . TYR C 1 429 ? 289.638 247.049 268.534 1.00 24.14  ? 429 TYR C CE2 1 
ATOM   8914  C  CZ  . TYR C 1 429 ? 289.880 246.058 267.612 1.00 24.48  ? 429 TYR C CZ  1 
ATOM   8915  O  OH  . TYR C 1 429 ? 289.171 246.037 266.436 1.00 24.09  ? 429 TYR C OH  1 
ATOM   8916  N  N   . ILE C 1 430 ? 294.772 247.992 271.564 1.00 29.87  ? 430 ILE C N   1 
ATOM   8917  C  CA  . ILE C 1 430 ? 295.369 249.269 271.193 1.00 29.69  ? 430 ILE C CA  1 
ATOM   8918  C  C   . ILE C 1 430 ? 296.610 249.099 270.329 1.00 28.19  ? 430 ILE C C   1 
ATOM   8919  O  O   . ILE C 1 430 ? 297.022 250.044 269.648 1.00 32.46  ? 430 ILE C O   1 
ATOM   8920  C  CB  . ILE C 1 430 ? 295.696 250.085 272.459 1.00 31.79  ? 430 ILE C CB  1 
ATOM   8921  C  CG1 . ILE C 1 430 ? 295.797 251.572 272.121 1.00 31.91  ? 430 ILE C CG1 1 
ATOM   8922  C  CG2 . ILE C 1 430 ? 296.982 249.587 273.093 1.00 25.37  ? 430 ILE C CG2 1 
ATOM   8923  C  CD1 . ILE C 1 430 ? 294.480 252.195 271.726 1.00 30.66  ? 430 ILE C CD1 1 
ATOM   8924  N  N   . LEU C 1 431 ? 297.222 247.918 270.337 1.00 27.39  ? 431 LEU C N   1 
ATOM   8925  C  CA  . LEU C 1 431 ? 298.452 247.670 269.597 1.00 26.05  ? 431 LEU C CA  1 
ATOM   8926  C  C   . LEU C 1 431 ? 298.208 247.160 268.183 1.00 26.16  ? 431 LEU C C   1 
ATOM   8927  O  O   . LEU C 1 431 ? 299.175 246.860 267.477 1.00 28.82  ? 431 LEU C O   1 
ATOM   8928  C  CB  . LEU C 1 431 ? 299.328 246.666 270.354 1.00 25.23  ? 431 LEU C CB  1 
ATOM   8929  C  CG  . LEU C 1 431 ? 299.789 247.053 271.760 1.00 26.28  ? 431 LEU C CG  1 
ATOM   8930  C  CD1 . LEU C 1 431 ? 300.625 245.942 272.371 1.00 25.45  ? 431 LEU C CD1 1 
ATOM   8931  C  CD2 . LEU C 1 431 ? 300.570 248.354 271.734 1.00 24.62  ? 431 LEU C CD2 1 
ATOM   8932  N  N   . LYS C 1 432 ? 296.953 247.058 267.750 1.00 24.80  ? 432 LYS C N   1 
ATOM   8933  C  CA  . LYS C 1 432 ? 296.611 246.476 266.459 1.00 22.74  ? 432 LYS C CA  1 
ATOM   8934  C  C   . LYS C 1 432 ? 296.126 247.520 265.458 1.00 21.32  ? 432 LYS C C   1 
ATOM   8935  O  O   . LYS C 1 432 ? 295.331 247.211 264.569 1.00 24.85  ? 432 LYS C O   1 
ATOM   8936  C  CB  . LYS C 1 432 ? 295.564 245.379 266.635 1.00 23.24  ? 432 LYS C CB  1 
ATOM   8937  C  CG  . LYS C 1 432 ? 295.764 244.546 267.885 1.00 25.62  ? 432 LYS C CG  1 
ATOM   8938  C  CD  . LYS C 1 432 ? 295.217 243.144 267.711 1.00 24.65  ? 432 LYS C CD  1 
ATOM   8939  C  CE  . LYS C 1 432 ? 295.618 242.258 268.875 1.00 26.53  ? 432 LYS C CE  1 
ATOM   8940  N  NZ  . LYS C 1 432 ? 294.530 241.331 269.275 1.00 31.16  ? 432 LYS C NZ  1 
ATOM   8941  N  N   . GLN C 1 433 ? 296.599 248.755 265.583 1.00 19.23  ? 433 GLN C N   1 
ATOM   8942  C  CA  . GLN C 1 433 ? 296.222 249.831 264.678 1.00 20.06  ? 433 GLN C CA  1 
ATOM   8943  C  C   . GLN C 1 433 ? 297.257 249.985 263.573 1.00 21.13  ? 433 GLN C C   1 
ATOM   8944  O  O   . GLN C 1 433 ? 298.464 249.919 263.821 1.00 22.50  ? 433 GLN C O   1 
ATOM   8945  C  CB  . GLN C 1 433 ? 296.068 251.152 265.429 1.00 22.07  ? 433 GLN C CB  1 
ATOM   8946  C  CG  . GLN C 1 433 ? 295.270 251.043 266.710 1.00 26.80  ? 433 GLN C CG  1 
ATOM   8947  C  CD  . GLN C 1 433 ? 294.739 252.381 267.172 1.00 31.37  ? 433 GLN C CD  1 
ATOM   8948  O  OE1 . GLN C 1 433 ? 293.760 252.894 266.630 1.00 33.51  ? 433 GLN C OE1 1 
ATOM   8949  N  NE2 . GLN C 1 433 ? 295.391 252.961 268.171 1.00 28.84  ? 433 GLN C NE2 1 
ATOM   8950  N  N   . LYS C 1 434 ? 296.774 250.192 262.352 1.00 22.02  ? 434 LYS C N   1 
ATOM   8951  C  CA  . LYS C 1 434 ? 297.612 250.380 261.180 1.00 17.99  ? 434 LYS C CA  1 
ATOM   8952  C  C   . LYS C 1 434 ? 297.274 251.702 260.507 1.00 19.15  ? 434 LYS C C   1 
ATOM   8953  O  O   . LYS C 1 434 ? 296.134 252.179 260.566 1.00 22.86  ? 434 LYS C O   1 
ATOM   8954  C  CB  . LYS C 1 434 ? 297.445 249.231 260.182 1.00 16.07  ? 434 LYS C CB  1 
ATOM   8955  C  CG  . LYS C 1 434 ? 297.371 247.860 260.822 1.00 15.21  ? 434 LYS C CG  1 
ATOM   8956  C  CD  . LYS C 1 434 ? 298.755 247.335 261.144 1.00 15.29  ? 434 LYS C CD  1 
ATOM   8957  C  CE  . LYS C 1 434 ? 298.684 246.122 262.047 1.00 15.56  ? 434 LYS C CE  1 
ATOM   8958  N  NZ  . LYS C 1 434 ? 300.027 245.732 262.544 1.00 22.74  ? 434 LYS C NZ  1 
ATOM   8959  N  N   . VAL C 1 435 ? 298.285 252.278 259.854 1.00 21.98  ? 435 VAL C N   1 
ATOM   8960  C  CA  . VAL C 1 435 ? 298.167 253.603 259.260 1.00 22.66  ? 435 VAL C CA  1 
ATOM   8961  C  C   . VAL C 1 435 ? 297.320 253.545 257.996 1.00 20.66  ? 435 VAL C C   1 
ATOM   8962  O  O   . VAL C 1 435 ? 297.403 252.595 257.207 1.00 21.95  ? 435 VAL C O   1 
ATOM   8963  C  CB  . VAL C 1 435 ? 299.564 254.176 258.965 1.00 20.41  ? 435 VAL C CB  1 
ATOM   8964  C  CG1 . VAL C 1 435 ? 299.454 255.544 258.316 1.00 23.23  ? 435 VAL C CG1 1 
ATOM   8965  C  CG2 . VAL C 1 435 ? 300.387 254.253 260.241 1.00 19.55  ? 435 VAL C CG2 1 
ATOM   8966  N  N   . VAL C 1 436 ? 296.499 254.574 257.802 1.00 21.33  ? 436 VAL C N   1 
ATOM   8967  C  CA  . VAL C 1 436 ? 295.659 254.738 256.622 1.00 19.33  ? 436 VAL C CA  1 
ATOM   8968  C  C   . VAL C 1 436 ? 295.966 256.095 256.001 1.00 20.56  ? 436 VAL C C   1 
ATOM   8969  O  O   . VAL C 1 436 ? 296.194 257.080 256.715 1.00 24.49  ? 436 VAL C O   1 
ATOM   8970  C  CB  . VAL C 1 436 ? 294.159 254.616 256.965 1.00 20.53  ? 436 VAL C CB  1 
ATOM   8971  C  CG1 . VAL C 1 436 ? 293.311 254.967 255.759 1.00 19.70  ? 436 VAL C CG1 1 
ATOM   8972  C  CG2 . VAL C 1 436 ? 293.841 253.214 257.447 1.00 15.43  ? 436 VAL C CG2 1 
ATOM   8973  N  N   . ARG C 1 437 ? 295.980 256.142 254.670 1.00 16.80  ? 437 ARG C N   1 
ATOM   8974  C  CA  . ARG C 1 437 ? 296.430 257.313 253.934 1.00 18.05  ? 437 ARG C CA  1 
ATOM   8975  C  C   . ARG C 1 437 ? 295.447 257.662 252.827 1.00 18.37  ? 437 ARG C C   1 
ATOM   8976  O  O   . ARG C 1 437 ? 294.768 256.792 252.277 1.00 20.67  ? 437 ARG C O   1 
ATOM   8977  C  CB  . ARG C 1 437 ? 297.813 257.076 253.320 1.00 14.91  ? 437 ARG C CB  1 
ATOM   8978  C  CG  . ARG C 1 437 ? 298.941 257.077 254.327 1.00 18.01  ? 437 ARG C CG  1 
ATOM   8979  C  CD  . ARG C 1 437 ? 298.747 258.147 255.379 1.00 24.08  ? 437 ARG C CD  1 
ATOM   8980  N  NE  . ARG C 1 437 ? 300.005 258.489 256.029 1.00 27.78  ? 437 ARG C NE  1 
ATOM   8981  C  CZ  . ARG C 1 437 ? 300.905 259.328 255.535 1.00 24.48  ? 437 ARG C CZ  1 
ATOM   8982  N  NH1 . ARG C 1 437 ? 300.720 259.935 254.377 1.00 24.55  ? 437 ARG C NH1 1 
ATOM   8983  N  NH2 . ARG C 1 437 ? 302.021 259.556 256.220 1.00 26.84  ? 437 ARG C NH2 1 
ATOM   8984  N  N   . GLY C 1 438 ? 295.376 258.954 252.510 1.00 17.92  ? 438 GLY C N   1 
ATOM   8985  C  CA  . GLY C 1 438 ? 294.700 259.400 251.309 1.00 20.12  ? 438 GLY C CA  1 
ATOM   8986  C  C   . GLY C 1 438 ? 293.411 260.168 251.508 1.00 18.89  ? 438 GLY C C   1 
ATOM   8987  O  O   . GLY C 1 438 ? 293.174 261.168 250.827 1.00 26.14  ? 438 GLY C O   1 
ATOM   8988  N  N   . GLY C 1 439 ? 292.572 259.714 252.429 1.00 20.46  ? 439 GLY C N   1 
ATOM   8989  C  CA  . GLY C 1 439 ? 291.243 260.266 252.574 1.00 18.05  ? 439 GLY C CA  1 
ATOM   8990  C  C   . GLY C 1 439 ? 290.237 259.584 251.662 1.00 17.99  ? 439 GLY C C   1 
ATOM   8991  O  O   . GLY C 1 439 ? 290.579 258.948 250.668 1.00 22.57  ? 439 GLY C O   1 
ATOM   8992  N  N   . SER C 1 440 ? 288.962 259.733 252.014 1.00 18.42  ? 440 SER C N   1 
ATOM   8993  C  CA  . SER C 1 440 ? 287.905 259.044 251.285 1.00 14.94  ? 440 SER C CA  1 
ATOM   8994  C  C   . SER C 1 440 ? 286.812 259.995 250.820 1.00 19.24  ? 440 SER C C   1 
ATOM   8995  O  O   . SER C 1 440 ? 286.940 261.217 250.936 1.00 23.76  ? 440 SER C O   1 
ATOM   8996  C  CB  . SER C 1 440 ? 287.292 257.943 252.151 1.00 17.28  ? 440 SER C CB  1 
ATOM   8997  O  OG  . SER C 1 440 ? 287.079 258.404 253.471 1.00 21.33  ? 440 SER C OG  1 
ATOM   8998  N  N   . TRP C 1 441 ? 285.727 259.423 250.294 1.00 20.20  ? 441 TRP C N   1 
ATOM   8999  C  CA  . TRP C 1 441 ? 284.597 260.208 249.818 1.00 16.71  ? 441 TRP C CA  1 
ATOM   9000  C  C   . TRP C 1 441 ? 283.898 260.967 250.937 1.00 17.79  ? 441 TRP C C   1 
ATOM   9001  O  O   . TRP C 1 441 ? 283.170 261.925 250.658 1.00 25.34  ? 441 TRP C O   1 
ATOM   9002  C  CB  . TRP C 1 441 ? 283.600 259.290 249.109 1.00 17.12  ? 441 TRP C CB  1 
ATOM   9003  C  CG  . TRP C 1 441 ? 283.168 258.114 249.944 1.00 17.65  ? 441 TRP C CG  1 
ATOM   9004  C  CD1 . TRP C 1 441 ? 283.805 256.914 250.055 1.00 17.88  ? 441 TRP C CD1 1 
ATOM   9005  C  CD2 . TRP C 1 441 ? 282.011 258.031 250.785 1.00 19.32  ? 441 TRP C CD2 1 
ATOM   9006  N  NE1 . TRP C 1 441 ? 283.118 256.090 250.909 1.00 17.09  ? 441 TRP C NE1 1 
ATOM   9007  C  CE2 . TRP C 1 441 ? 282.013 256.752 251.372 1.00 17.01  ? 441 TRP C CE2 1 
ATOM   9008  C  CE3 . TRP C 1 441 ? 280.975 258.915 251.100 1.00 19.52  ? 441 TRP C CE3 1 
ATOM   9009  C  CZ2 . TRP C 1 441 ? 281.020 256.333 252.252 1.00 18.34  ? 441 TRP C CZ2 1 
ATOM   9010  C  CZ3 . TRP C 1 441 ? 279.991 258.497 251.975 1.00 18.23  ? 441 TRP C CZ3 1 
ATOM   9011  C  CH2 . TRP C 1 441 ? 280.020 257.219 252.540 1.00 20.86  ? 441 TRP C CH2 1 
ATOM   9012  N  N   . LYS C 1 442 ? 284.092 260.561 252.190 1.00 16.36  ? 442 LYS C N   1 
ATOM   9013  C  CA  . LYS C 1 442 ? 283.432 261.188 253.326 1.00 19.47  ? 442 LYS C CA  1 
ATOM   9014  C  C   . LYS C 1 442 ? 284.365 262.082 254.134 1.00 23.18  ? 442 LYS C C   1 
ATOM   9015  O  O   . LYS C 1 442 ? 284.010 262.489 255.244 1.00 20.66  ? 442 LYS C O   1 
ATOM   9016  C  CB  . LYS C 1 442 ? 282.816 260.118 254.231 1.00 21.21  ? 442 LYS C CB  1 
ATOM   9017  C  CG  . LYS C 1 442 ? 283.816 259.116 254.768 1.00 20.43  ? 442 LYS C CG  1 
ATOM   9018  C  CD  . LYS C 1 442 ? 284.300 259.511 256.149 1.00 22.86  ? 442 LYS C CD  1 
ATOM   9019  C  CE  . LYS C 1 442 ? 285.673 258.938 256.427 1.00 19.74  ? 442 LYS C CE  1 
ATOM   9020  N  NZ  . LYS C 1 442 ? 286.208 259.402 257.730 1.00 22.65  ? 442 LYS C NZ  1 
ATOM   9021  N  N   . ASP C 1 443 ? 285.542 262.401 253.608 1.00 21.90  ? 443 ASP C N   1 
ATOM   9022  C  CA  . ASP C 1 443 ? 286.529 263.190 254.328 1.00 20.76  ? 443 ASP C CA  1 
ATOM   9023  C  C   . ASP C 1 443 ? 286.516 264.637 253.855 1.00 21.59  ? 443 ASP C C   1 
ATOM   9024  O  O   . ASP C 1 443 ? 286.171 264.935 252.710 1.00 23.25  ? 443 ASP C O   1 
ATOM   9025  C  CB  . ASP C 1 443 ? 287.932 262.603 254.150 1.00 22.16  ? 443 ASP C CB  1 
ATOM   9026  C  CG  . ASP C 1 443 ? 288.217 261.467 255.113 1.00 29.88  ? 443 ASP C CG  1 
ATOM   9027  O  OD1 . ASP C 1 443 ? 287.911 261.611 256.315 1.00 31.54  ? 443 ASP C OD1 1 
ATOM   9028  O  OD2 . ASP C 1 443 ? 288.750 260.429 254.670 1.00 32.12  ? 443 ASP C OD2 1 
ATOM   9029  N  N   . VAL C 1 444 ? 286.896 265.538 254.760 1.00 23.68  ? 444 VAL C N   1 
ATOM   9030  C  CA  . VAL C 1 444 ? 287.065 266.949 254.431 1.00 24.34  ? 444 VAL C CA  1 
ATOM   9031  C  C   . VAL C 1 444 ? 288.437 267.135 253.797 1.00 21.87  ? 444 VAL C C   1 
ATOM   9032  O  O   . VAL C 1 444 ? 289.277 266.230 253.836 1.00 28.05  ? 444 VAL C O   1 
ATOM   9033  C  CB  . VAL C 1 444 ? 286.891 267.847 255.670 1.00 23.06  ? 444 VAL C CB  1 
ATOM   9034  C  CG1 . VAL C 1 444 ? 285.520 267.638 256.290 1.00 25.68  ? 444 VAL C CG1 1 
ATOM   9035  C  CG2 . VAL C 1 444 ? 287.988 267.578 256.684 1.00 23.75  ? 444 VAL C CG2 1 
ATOM   9036  N  N   . ALA C 1 445 ? 288.671 268.308 253.204 1.00 23.73  ? 445 ALA C N   1 
ATOM   9037  C  CA  . ALA C 1 445 ? 289.890 268.519 252.428 1.00 24.24  ? 445 ALA C CA  1 
ATOM   9038  C  C   . ALA C 1 445 ? 291.146 268.292 253.259 1.00 29.28  ? 445 ALA C C   1 
ATOM   9039  O  O   . ALA C 1 445 ? 292.199 267.951 252.709 1.00 28.21  ? 445 ALA C O   1 
ATOM   9040  C  CB  . ALA C 1 445 ? 289.899 269.928 251.835 1.00 18.68  ? 445 ALA C CB  1 
ATOM   9041  N  N   . ARG C 1 446 ? 291.060 268.474 254.576 1.00 30.52  ? 446 ARG C N   1 
ATOM   9042  C  CA  . ARG C 1 446 ? 292.233 268.284 255.420 1.00 22.49  ? 446 ARG C CA  1 
ATOM   9043  C  C   . ARG C 1 446 ? 292.736 266.847 255.359 1.00 25.93  ? 446 ARG C C   1 
ATOM   9044  O  O   . ARG C 1 446 ? 293.947 266.608 255.290 1.00 29.71  ? 446 ARG C O   1 
ATOM   9045  C  CB  . ARG C 1 446 ? 291.912 268.671 256.861 1.00 24.21  ? 446 ARG C CB  1 
ATOM   9046  C  CG  . ARG C 1 446 ? 293.134 268.790 257.742 1.00 34.30  ? 446 ARG C CG  1 
ATOM   9047  C  CD  . ARG C 1 446 ? 292.967 268.001 259.022 1.00 32.72  ? 446 ARG C CD  1 
ATOM   9048  N  NE  . ARG C 1 446 ? 294.098 268.196 259.919 1.00 39.21  ? 446 ARG C NE  1 
ATOM   9049  C  CZ  . ARG C 1 446 ? 294.546 267.281 260.766 1.00 42.14  ? 446 ARG C CZ  1 
ATOM   9050  N  NH1 . ARG C 1 446 ? 293.978 266.091 260.863 1.00 41.58  ? 446 ARG C NH1 1 
ATOM   9051  N  NH2 . ARG C 1 446 ? 295.593 267.568 261.534 1.00 47.95  ? 446 ARG C NH2 1 
ATOM   9052  N  N   . PHE C 1 447 ? 291.825 265.877 255.385 1.00 26.47  ? 447 PHE C N   1 
ATOM   9053  C  CA  . PHE C 1 447 ? 292.223 264.479 255.465 1.00 23.02  ? 447 PHE C CA  1 
ATOM   9054  C  C   . PHE C 1 447 ? 292.544 263.866 254.111 1.00 23.05  ? 447 PHE C C   1 
ATOM   9055  O  O   . PHE C 1 447 ? 293.068 262.749 254.068 1.00 24.52  ? 447 PHE C O   1 
ATOM   9056  C  CB  . PHE C 1 447 ? 291.133 263.664 256.161 1.00 21.46  ? 447 PHE C CB  1 
ATOM   9057  C  CG  . PHE C 1 447 ? 291.038 263.927 257.633 1.00 24.65  ? 447 PHE C CG  1 
ATOM   9058  C  CD1 . PHE C 1 447 ? 291.809 263.208 258.526 1.00 29.31  ? 447 PHE C CD1 1 
ATOM   9059  C  CD2 . PHE C 1 447 ? 290.187 264.899 258.122 1.00 28.31  ? 447 PHE C CD2 1 
ATOM   9060  C  CE1 . PHE C 1 447 ? 291.730 263.450 259.879 1.00 29.12  ? 447 PHE C CE1 1 
ATOM   9061  C  CE2 . PHE C 1 447 ? 290.102 265.145 259.474 1.00 28.71  ? 447 PHE C CE2 1 
ATOM   9062  C  CZ  . PHE C 1 447 ? 290.875 264.419 260.354 1.00 29.46  ? 447 PHE C CZ  1 
ATOM   9063  N  N   . ILE C 1 448 ? 292.251 264.563 253.008 1.00 21.36  ? 448 ILE C N   1 
ATOM   9064  C  CA  . ILE C 1 448 ? 292.704 264.119 251.696 1.00 19.55  ? 448 ILE C CA  1 
ATOM   9065  C  C   . ILE C 1 448 ? 294.070 264.686 251.348 1.00 24.09  ? 448 ILE C C   1 
ATOM   9066  O  O   . ILE C 1 448 ? 294.594 264.401 250.263 1.00 27.95  ? 448 ILE C O   1 
ATOM   9067  C  CB  . ILE C 1 448 ? 291.676 264.479 250.603 1.00 23.77  ? 448 ILE C CB  1 
ATOM   9068  C  CG1 . ILE C 1 448 ? 291.640 265.988 250.366 1.00 23.59  ? 448 ILE C CG1 1 
ATOM   9069  C  CG2 . ILE C 1 448 ? 290.297 263.963 250.981 1.00 23.26  ? 448 ILE C CG2 1 
ATOM   9070  C  CD1 . ILE C 1 448 ? 291.332 266.366 248.940 1.00 17.55  ? 448 ILE C CD1 1 
ATOM   9071  N  N   . ARG C 1 449 ? 294.661 265.487 252.232 1.00 25.56  ? 449 ARG C N   1 
ATOM   9072  C  CA  . ARG C 1 449 ? 296.047 265.898 252.071 1.00 22.95  ? 449 ARG C CA  1 
ATOM   9073  C  C   . ARG C 1 449 ? 296.963 264.688 252.201 1.00 28.61  ? 449 ARG C C   1 
ATOM   9074  O  O   . ARG C 1 449 ? 296.760 263.826 253.060 1.00 31.67  ? 449 ARG C O   1 
ATOM   9075  C  CB  . ARG C 1 449 ? 296.411 266.952 253.115 1.00 26.27  ? 449 ARG C CB  1 
ATOM   9076  C  CG  . ARG C 1 449 ? 296.448 268.372 252.586 1.00 30.20  ? 449 ARG C CG  1 
ATOM   9077  C  CD  . ARG C 1 449 ? 296.300 269.380 253.713 1.00 33.31  ? 449 ARG C CD  1 
ATOM   9078  N  NE  . ARG C 1 449 ? 295.108 270.203 253.549 1.00 37.82  ? 449 ARG C NE  1 
ATOM   9079  C  CZ  . ARG C 1 449 ? 294.554 270.922 254.515 1.00 44.93  ? 449 ARG C CZ  1 
ATOM   9080  N  NH1 . ARG C 1 449 ? 295.059 270.945 255.737 1.00 41.90  ? 449 ARG C NH1 1 
ATOM   9081  N  NH2 . ARG C 1 449 ? 293.466 271.639 254.247 1.00 38.83  ? 449 ARG C NH2 1 
ATOM   9082  N  N   . SER C 1 450 ? 297.983 264.628 251.345 1.00 23.63  ? 450 SER C N   1 
ATOM   9083  C  CA  . SER C 1 450 ? 298.834 263.445 251.298 1.00 20.81  ? 450 SER C CA  1 
ATOM   9084  C  C   . SER C 1 450 ? 299.630 263.233 252.580 1.00 27.06  ? 450 SER C C   1 
ATOM   9085  O  O   . SER C 1 450 ? 300.059 262.106 252.842 1.00 31.88  ? 450 SER C O   1 
ATOM   9086  C  CB  . SER C 1 450 ? 299.789 263.529 250.107 1.00 24.64  ? 450 SER C CB  1 
ATOM   9087  O  OG  . SER C 1 450 ? 299.078 263.523 248.883 1.00 26.53  ? 450 SER C OG  1 
ATOM   9088  N  N   . ALA C 1 451 ? 299.839 264.276 253.381 1.00 26.95  ? 451 ALA C N   1 
ATOM   9089  C  CA  . ALA C 1 451 ? 300.641 264.149 254.590 1.00 25.16  ? 451 ALA C CA  1 
ATOM   9090  C  C   . ALA C 1 451 ? 299.827 263.779 255.823 1.00 27.94  ? 451 ALA C C   1 
ATOM   9091  O  O   . ALA C 1 451 ? 300.418 263.487 256.868 1.00 29.65  ? 451 ALA C O   1 
ATOM   9092  C  CB  . ALA C 1 451 ? 301.401 265.451 254.861 1.00 26.24  ? 451 ALA C CB  1 
ATOM   9093  N  N   . THR C 1 452 ? 298.501 263.783 255.734 1.00 26.36  ? 452 THR C N   1 
ATOM   9094  C  CA  . THR C 1 452 ? 297.663 263.466 256.882 1.00 24.11  ? 452 THR C CA  1 
ATOM   9095  C  C   . THR C 1 452 ? 297.616 261.959 257.099 1.00 28.00  ? 452 THR C C   1 
ATOM   9096  O  O   . THR C 1 452 ? 297.435 261.190 256.151 1.00 33.23  ? 452 THR C O   1 
ATOM   9097  C  CB  . THR C 1 452 ? 296.253 264.018 256.684 1.00 26.66  ? 452 THR C CB  1 
ATOM   9098  O  OG1 . THR C 1 452 ? 296.328 265.411 256.362 1.00 31.17  ? 452 THR C OG1 1 
ATOM   9099  C  CG2 . THR C 1 452 ? 295.432 263.845 257.950 1.00 25.85  ? 452 THR C CG2 1 
ATOM   9100  N  N   . ARG C 1 453 ? 297.788 261.541 258.349 1.00 26.31  ? 453 ARG C N   1 
ATOM   9101  C  CA  . ARG C 1 453 ? 297.777 260.136 258.729 1.00 24.98  ? 453 ARG C CA  1 
ATOM   9102  C  C   . ARG C 1 453 ? 296.498 259.826 259.491 1.00 28.16  ? 453 ARG C C   1 
ATOM   9103  O  O   . ARG C 1 453 ? 296.139 260.553 260.423 1.00 34.23  ? 453 ARG C O   1 
ATOM   9104  C  CB  . ARG C 1 453 ? 298.983 259.791 259.606 1.00 25.88  ? 453 ARG C CB  1 
ATOM   9105  C  CG  . ARG C 1 453 ? 300.292 260.429 259.190 1.00 27.98  ? 453 ARG C CG  1 
ATOM   9106  C  CD  . ARG C 1 453 ? 301.310 260.344 260.317 1.00 28.70  ? 453 ARG C CD  1 
ATOM   9107  N  NE  . ARG C 1 453 ? 301.846 258.999 260.490 1.00 33.89  ? 453 ARG C NE  1 
ATOM   9108  C  CZ  . ARG C 1 453 ? 302.084 258.434 261.666 1.00 32.12  ? 453 ARG C CZ  1 
ATOM   9109  N  NH1 . ARG C 1 453 ? 301.845 259.071 262.800 1.00 28.88  ? 453 ARG C NH1 1 
ATOM   9110  N  NH2 . ARG C 1 453 ? 302.577 257.200 261.706 1.00 27.29  ? 453 ARG C NH2 1 
ATOM   9111  N  N   . SER C 1 454 ? 295.816 258.756 259.105 1.00 24.98  ? 454 SER C N   1 
ATOM   9112  C  CA  . SER C 1 454 ? 294.741 258.198 259.904 1.00 26.30  ? 454 SER C CA  1 
ATOM   9113  C  C   . SER C 1 454 ? 295.161 256.804 260.348 1.00 24.88  ? 454 SER C C   1 
ATOM   9114  O  O   . SER C 1 454 ? 296.253 256.336 260.034 1.00 24.53  ? 454 SER C O   1 
ATOM   9115  C  CB  . SER C 1 454 ? 293.430 258.168 259.114 1.00 27.00  ? 454 SER C CB  1 
ATOM   9116  O  OG  . SER C 1 454 ? 292.655 259.322 259.380 1.00 36.26  ? 454 SER C OG  1 
ATOM   9117  N  N   . HIS C 1 455 ? 294.277 256.119 261.062 1.00 25.57  ? 455 HIS C N   1 
ATOM   9118  C  CA  . HIS C 1 455 ? 294.591 254.764 261.479 1.00 23.04  ? 455 HIS C CA  1 
ATOM   9119  C  C   . HIS C 1 455 ? 293.299 253.992 261.677 1.00 21.57  ? 455 HIS C C   1 
ATOM   9120  O  O   . HIS C 1 455 ? 292.224 254.570 261.848 1.00 25.50  ? 455 HIS C O   1 
ATOM   9121  C  CB  . HIS C 1 455 ? 295.432 254.750 262.759 1.00 23.72  ? 455 HIS C CB  1 
ATOM   9122  C  CG  . HIS C 1 455 ? 294.968 255.723 263.795 1.00 26.26  ? 455 HIS C CG  1 
ATOM   9123  N  ND1 . HIS C 1 455 ? 294.239 255.340 264.898 1.00 27.90  ? 455 HIS C ND1 1 
ATOM   9124  C  CD2 . HIS C 1 455 ? 295.119 257.065 263.890 1.00 25.49  ? 455 HIS C CD2 1 
ATOM   9125  C  CE1 . HIS C 1 455 ? 293.965 256.403 265.633 1.00 32.74  ? 455 HIS C CE1 1 
ATOM   9126  N  NE2 . HIS C 1 455 ? 294.487 257.463 265.042 1.00 33.73  ? 455 HIS C NE2 1 
ATOM   9127  N  N   . GLU C 1 456 ? 293.424 252.670 261.642 1.00 20.31  ? 456 GLU C N   1 
ATOM   9128  C  CA  . GLU C 1 456 ? 292.285 251.801 261.894 1.00 17.77  ? 456 GLU C CA  1 
ATOM   9129  C  C   . GLU C 1 456 ? 292.784 250.475 262.443 1.00 21.12  ? 456 GLU C C   1 
ATOM   9130  O  O   . GLU C 1 456 ? 293.918 250.070 262.183 1.00 22.42  ? 456 GLU C O   1 
ATOM   9131  C  CB  . GLU C 1 456 ? 291.454 251.581 260.623 1.00 19.03  ? 456 GLU C CB  1 
ATOM   9132  C  CG  . GLU C 1 456 ? 290.150 250.837 260.850 1.00 18.20  ? 456 GLU C CG  1 
ATOM   9133  C  CD  . GLU C 1 456 ? 289.252 251.523 261.860 1.00 28.67  ? 456 GLU C CD  1 
ATOM   9134  O  OE1 . GLU C 1 456 ? 288.537 252.472 261.476 1.00 36.99  ? 456 GLU C OE1 1 
ATOM   9135  O  OE2 . GLU C 1 456 ? 289.254 251.113 263.038 1.00 30.04  ? 456 GLU C OE2 1 
ATOM   9136  N  N   . TYR C 1 457 ? 291.930 249.803 263.206 1.00 23.17  ? 457 TYR C N   1 
ATOM   9137  C  CA  . TYR C 1 457 ? 292.281 248.494 263.734 1.00 16.69  ? 457 TYR C CA  1 
ATOM   9138  C  C   . TYR C 1 457 ? 292.349 247.469 262.610 1.00 19.81  ? 457 TYR C C   1 
ATOM   9139  O  O   . TYR C 1 457 ? 291.565 247.510 261.659 1.00 21.90  ? 457 TYR C O   1 
ATOM   9140  C  CB  . TYR C 1 457 ? 291.275 248.060 264.796 1.00 20.70  ? 457 TYR C CB  1 
ATOM   9141  C  CG  . TYR C 1 457 ? 291.280 248.938 266.023 1.00 21.47  ? 457 TYR C CG  1 
ATOM   9142  C  CD1 . TYR C 1 457 ? 292.273 248.811 266.984 1.00 20.96  ? 457 TYR C CD1 1 
ATOM   9143  C  CD2 . TYR C 1 457 ? 290.299 249.899 266.217 1.00 19.02  ? 457 TYR C CD2 1 
ATOM   9144  C  CE1 . TYR C 1 457 ? 292.284 249.610 268.106 1.00 21.65  ? 457 TYR C CE1 1 
ATOM   9145  C  CE2 . TYR C 1 457 ? 290.302 250.702 267.335 1.00 18.97  ? 457 TYR C CE2 1 
ATOM   9146  C  CZ  . TYR C 1 457 ? 291.297 250.554 268.276 1.00 24.24  ? 457 TYR C CZ  1 
ATOM   9147  O  OH  . TYR C 1 457 ? 291.304 251.355 269.394 1.00 38.42  ? 457 TYR C OH  1 
ATOM   9148  N  N   . GLN C 1 458 ? 293.291 246.533 262.736 1.00 19.84  ? 458 GLN C N   1 
ATOM   9149  C  CA  . GLN C 1 458 ? 293.616 245.636 261.635 1.00 17.50  ? 458 GLN C CA  1 
ATOM   9150  C  C   . GLN C 1 458 ? 292.461 244.721 261.250 1.00 19.86  ? 458 GLN C C   1 
ATOM   9151  O  O   . GLN C 1 458 ? 292.425 244.238 260.114 1.00 23.53  ? 458 GLN C O   1 
ATOM   9152  C  CB  . GLN C 1 458 ? 294.843 244.800 261.997 1.00 18.73  ? 458 GLN C CB  1 
ATOM   9153  C  CG  . GLN C 1 458 ? 294.677 243.963 263.251 1.00 18.72  ? 458 GLN C CG  1 
ATOM   9154  C  CD  . GLN C 1 458 ? 295.870 243.075 263.515 1.00 22.30  ? 458 GLN C CD  1 
ATOM   9155  O  OE1 . GLN C 1 458 ? 296.997 243.553 263.630 1.00 26.20  ? 458 GLN C OE1 1 
ATOM   9156  N  NE2 . GLN C 1 458 ? 295.632 241.775 263.605 1.00 29.83  ? 458 GLN C NE2 1 
ATOM   9157  N  N   . ASN C 1 459 ? 291.524 244.462 262.159 1.00 18.55  ? 459 ASN C N   1 
ATOM   9158  C  CA  . ASN C 1 459 ? 290.424 243.548 261.888 1.00 19.03  ? 459 ASN C CA  1 
ATOM   9159  C  C   . ASN C 1 459 ? 289.132 244.269 261.522 1.00 19.35  ? 459 ASN C C   1 
ATOM   9160  O  O   . ASN C 1 459 ? 288.074 243.635 261.475 1.00 20.81  ? 459 ASN C O   1 
ATOM   9161  C  CB  . ASN C 1 459 ? 290.192 242.630 263.090 1.00 17.87  ? 459 ASN C CB  1 
ATOM   9162  C  CG  . ASN C 1 459 ? 289.763 243.384 264.332 1.00 19.12  ? 459 ASN C CG  1 
ATOM   9163  O  OD1 . ASN C 1 459 ? 289.881 244.606 264.403 1.00 22.63  ? 459 ASN C OD1 1 
ATOM   9164  N  ND2 . ASN C 1 459 ? 289.261 242.656 265.320 1.00 19.97  ? 459 ASN C ND2 1 
ATOM   9165  N  N   . VAL C 1 460 ? 289.196 245.567 261.245 1.00 18.25  ? 460 VAL C N   1 
ATOM   9166  C  CA  . VAL C 1 460 ? 288.016 246.388 261.003 1.00 17.72  ? 460 VAL C CA  1 
ATOM   9167  C  C   . VAL C 1 460 ? 287.973 246.773 259.531 1.00 19.50  ? 460 VAL C C   1 
ATOM   9168  O  O   . VAL C 1 460 ? 288.976 247.228 258.970 1.00 22.95  ? 460 VAL C O   1 
ATOM   9169  C  CB  . VAL C 1 460 ? 288.012 247.641 261.895 1.00 20.95  ? 460 VAL C CB  1 
ATOM   9170  C  CG1 . VAL C 1 460 ? 286.902 248.586 261.473 1.00 20.20  ? 460 VAL C CG1 1 
ATOM   9171  C  CG2 . VAL C 1 460 ? 287.856 247.249 263.353 1.00 18.88  ? 460 VAL C CG2 1 
ATOM   9172  N  N   . GLY C 1 461 ? 286.815 246.582 258.909 1.00 17.82  ? 461 GLY C N   1 
ATOM   9173  C  CA  . GLY C 1 461 ? 286.568 247.024 257.545 1.00 18.54  ? 461 GLY C CA  1 
ATOM   9174  C  C   . GLY C 1 461 ? 285.585 248.181 257.547 1.00 21.52  ? 461 GLY C C   1 
ATOM   9175  O  O   . GLY C 1 461 ? 284.667 248.223 258.370 1.00 23.11  ? 461 GLY C O   1 
ATOM   9176  N  N   . ARG C 1 462 ? 285.787 249.120 256.627 1.00 21.47  ? 462 ARG C N   1 
ATOM   9177  C  CA  . ARG C 1 462 ? 284.985 250.331 256.556 1.00 22.26  ? 462 ARG C CA  1 
ATOM   9178  C  C   . ARG C 1 462 ? 284.513 250.557 255.129 1.00 21.59  ? 462 ARG C C   1 
ATOM   9179  O  O   . ARG C 1 462 ? 285.143 250.105 254.171 1.00 25.40  ? 462 ARG C O   1 
ATOM   9180  C  CB  . ARG C 1 462 ? 285.774 251.555 257.035 1.00 18.72  ? 462 ARG C CB  1 
ATOM   9181  C  CG  . ARG C 1 462 ? 286.179 251.498 258.492 1.00 21.22  ? 462 ARG C CG  1 
ATOM   9182  C  CD  . ARG C 1 462 ? 285.137 252.133 259.382 1.00 22.35  ? 462 ARG C CD  1 
ATOM   9183  N  NE  . ARG C 1 462 ? 285.493 252.026 260.791 1.00 26.29  ? 462 ARG C NE  1 
ATOM   9184  C  CZ  . ARG C 1 462 ? 284.715 252.417 261.789 1.00 29.59  ? 462 ARG C CZ  1 
ATOM   9185  N  NH1 . ARG C 1 462 ? 283.524 252.949 261.570 1.00 30.80  ? 462 ARG C NH1 1 
ATOM   9186  N  NH2 . ARG C 1 462 ? 285.142 252.271 263.039 1.00 28.11  ? 462 ARG C NH2 1 
ATOM   9187  N  N   . SER C 1 463 ? 283.398 251.268 254.996 1.00 21.10  ? 463 SER C N   1 
ATOM   9188  C  CA  . SER C 1 463 ? 282.853 251.616 253.686 1.00 20.96  ? 463 SER C CA  1 
ATOM   9189  C  C   . SER C 1 463 ? 283.619 252.729 253.009 1.00 18.31  ? 463 SER C C   1 
ATOM   9190  O  O   . SER C 1 463 ? 283.185 253.207 251.954 1.00 20.61  ? 463 SER C O   1 
ATOM   9191  C  CB  . SER C 1 463 ? 281.380 252.005 253.814 1.00 18.42  ? 463 SER C CB  1 
ATOM   9192  O  OG  . SER C 1 463 ? 281.165 252.824 254.948 1.00 21.42  ? 463 SER C OG  1 
ATOM   9193  N  N   . TYR C 1 464 ? 284.744 253.161 253.580 1.00 18.56  ? 464 TYR C N   1 
ATOM   9194  C  CA  . TYR C 1 464 ? 285.542 254.236 253.004 1.00 15.51  ? 464 TYR C CA  1 
ATOM   9195  C  C   . TYR C 1 464 ? 287.032 253.913 253.014 1.00 17.66  ? 464 TYR C C   1 
ATOM   9196  O  O   . TYR C 1 464 ? 287.855 254.814 252.827 1.00 19.83  ? 464 TYR C O   1 
ATOM   9197  C  CB  . TYR C 1 464 ? 285.279 255.553 253.736 1.00 17.38  ? 464 TYR C CB  1 
ATOM   9198  C  CG  . TYR C 1 464 ? 285.349 255.454 255.240 1.00 18.99  ? 464 TYR C CG  1 
ATOM   9199  C  CD1 . TYR C 1 464 ? 286.570 255.459 255.900 1.00 15.45  ? 464 TYR C CD1 1 
ATOM   9200  C  CD2 . TYR C 1 464 ? 284.193 255.365 256.002 1.00 20.42  ? 464 TYR C CD2 1 
ATOM   9201  C  CE1 . TYR C 1 464 ? 286.638 255.374 257.271 1.00 16.19  ? 464 TYR C CE1 1 
ATOM   9202  C  CE2 . TYR C 1 464 ? 284.252 255.281 257.376 1.00 20.41  ? 464 TYR C CE2 1 
ATOM   9203  C  CZ  . TYR C 1 464 ? 285.476 255.285 258.005 1.00 22.56  ? 464 TYR C CZ  1 
ATOM   9204  O  OH  . TYR C 1 464 ? 285.541 255.202 259.374 1.00 29.17  ? 464 TYR C OH  1 
ATOM   9205  N  N   . ILE C 1 465 ? 287.399 252.652 253.222 1.00 16.46  ? 465 ILE C N   1 
ATOM   9206  C  CA  . ILE C 1 465 ? 288.792 252.224 253.198 1.00 17.48  ? 465 ILE C CA  1 
ATOM   9207  C  C   . ILE C 1 465 ? 288.940 251.116 252.165 1.00 17.77  ? 465 ILE C C   1 
ATOM   9208  O  O   . ILE C 1 465 ? 288.281 250.073 252.264 1.00 22.87  ? 465 ILE C O   1 
ATOM   9209  C  CB  . ILE C 1 465 ? 289.273 251.750 254.578 1.00 19.12  ? 465 ILE C CB  1 
ATOM   9210  C  CG1 . ILE C 1 465 ? 289.173 252.886 255.596 1.00 19.32  ? 465 ILE C CG1 1 
ATOM   9211  C  CG2 . ILE C 1 465 ? 290.701 251.240 254.492 1.00 12.68  ? 465 ILE C CG2 1 
ATOM   9212  C  CD1 . ILE C 1 465 ? 289.466 252.459 257.012 1.00 14.22  ? 465 ILE C CD1 1 
ATOM   9213  N  N   . GLY C 1 466 ? 289.805 251.342 251.181 1.00 15.32  ? 466 GLY C N   1 
ATOM   9214  C  CA  . GLY C 1 466 ? 290.204 250.318 250.238 1.00 15.52  ? 466 GLY C CA  1 
ATOM   9215  C  C   . GLY C 1 466 ? 291.694 250.064 250.328 1.00 13.80  ? 466 GLY C C   1 
ATOM   9216  O  O   . GLY C 1 466 ? 292.266 250.137 251.419 1.00 18.74  ? 466 GLY C O   1 
ATOM   9217  N  N   . PHE C 1 467 ? 292.340 249.768 249.205 1.00 17.65  ? 467 PHE C N   1 
ATOM   9218  C  CA  . PHE C 1 467 ? 293.781 249.554 249.225 1.00 15.33  ? 467 PHE C CA  1 
ATOM   9219  C  C   . PHE C 1 467 ? 294.260 249.292 247.807 1.00 15.34  ? 467 PHE C C   1 
ATOM   9220  O  O   . PHE C 1 467 ? 293.475 248.947 246.920 1.00 18.13  ? 467 PHE C O   1 
ATOM   9221  C  CB  . PHE C 1 467 ? 294.175 248.386 250.138 1.00 12.79  ? 467 PHE C CB  1 
ATOM   9222  C  CG  . PHE C 1 467 ? 293.802 247.037 249.592 1.00 12.83  ? 467 PHE C CG  1 
ATOM   9223  C  CD1 . PHE C 1 467 ? 292.488 246.603 249.615 1.00 12.12  ? 467 PHE C CD1 1 
ATOM   9224  C  CD2 . PHE C 1 467 ? 294.768 246.201 249.060 1.00 13.70  ? 467 PHE C CD2 1 
ATOM   9225  C  CE1 . PHE C 1 467 ? 292.145 245.366 249.112 1.00 13.36  ? 467 PHE C CE1 1 
ATOM   9226  C  CE2 . PHE C 1 467 ? 294.430 244.962 248.558 1.00 13.02  ? 467 PHE C CE2 1 
ATOM   9227  C  CZ  . PHE C 1 467 ? 293.117 244.543 248.585 1.00 16.21  ? 467 PHE C CZ  1 
ATOM   9228  N  N   . ARG C 1 468 ? 295.562 249.473 247.606 1.00 17.33  ? 468 ARG C N   1 
ATOM   9229  C  CA  . ARG C 1 468 ? 296.240 249.070 246.385 1.00 17.09  ? 468 ARG C CA  1 
ATOM   9230  C  C   . ARG C 1 468 ? 297.562 248.426 246.772 1.00 19.25  ? 468 ARG C C   1 
ATOM   9231  O  O   . ARG C 1 468 ? 298.056 248.603 247.887 1.00 20.81  ? 468 ARG C O   1 
ATOM   9232  C  CB  . ARG C 1 468 ? 296.459 250.252 245.431 1.00 16.01  ? 468 ARG C CB  1 
ATOM   9233  C  CG  . ARG C 1 468 ? 297.423 251.308 245.936 1.00 17.33  ? 468 ARG C CG  1 
ATOM   9234  C  CD  . ARG C 1 468 ? 297.491 252.478 244.970 1.00 18.09  ? 468 ARG C CD  1 
ATOM   9235  N  NE  . ARG C 1 468 ? 296.366 253.390 245.136 1.00 20.17  ? 468 ARG C NE  1 
ATOM   9236  C  CZ  . ARG C 1 468 ? 295.916 254.207 244.193 1.00 17.67  ? 468 ARG C CZ  1 
ATOM   9237  N  NH1 . ARG C 1 468 ? 296.470 254.250 242.994 1.00 17.84  ? 468 ARG C NH1 1 
ATOM   9238  N  NH2 . ARG C 1 468 ? 294.883 254.999 244.462 1.00 15.43  ? 468 ARG C NH2 1 
ATOM   9239  N  N   . CYS C 1 469 ? 298.132 247.671 245.842 1.00 20.42  ? 469 CYS C N   1 
ATOM   9240  C  CA  . CYS C 1 469 ? 299.314 246.870 246.118 1.00 18.60  ? 469 CYS C CA  1 
ATOM   9241  C  C   . CYS C 1 469 ? 300.562 247.497 245.508 1.00 17.21  ? 469 CYS C C   1 
ATOM   9242  O  O   . CYS C 1 469 ? 300.497 248.287 244.564 1.00 21.88  ? 469 CYS C O   1 
ATOM   9243  C  CB  . CYS C 1 469 ? 299.135 245.446 245.588 1.00 22.62  ? 469 CYS C CB  1 
ATOM   9244  S  SG  . CYS C 1 469 ? 297.557 244.685 246.024 1.00 41.58  ? 469 CYS C SG  1 
ATOM   9245  N  N   . VAL C 1 470 ? 301.711 247.126 246.070 1.00 17.46  ? 470 VAL C N   1 
ATOM   9246  C  CA  . VAL C 1 470 ? 303.011 247.546 245.573 1.00 19.07  ? 470 VAL C CA  1 
ATOM   9247  C  C   . VAL C 1 470 ? 303.899 246.315 245.446 1.00 20.99  ? 470 VAL C C   1 
ATOM   9248  O  O   . VAL C 1 470 ? 303.604 245.246 245.980 1.00 23.54  ? 470 VAL C O   1 
ATOM   9249  C  CB  . VAL C 1 470 ? 303.680 248.606 246.475 1.00 18.90  ? 470 VAL C CB  1 
ATOM   9250  C  CG1 . VAL C 1 470 ? 302.862 249.889 246.490 1.00 14.46  ? 470 VAL C CG1 1 
ATOM   9251  C  CG2 . VAL C 1 470 ? 303.869 248.066 247.880 1.00 16.21  ? 470 VAL C CG2 1 
ATOM   9252  N  N   . ARG C 1 471 ? 304.996 246.482 244.717 1.00 21.28  ? 471 ARG C N   1 
ATOM   9253  C  CA  . ARG C 1 471 ? 305.958 245.401 244.528 1.00 22.20  ? 471 ARG C CA  1 
ATOM   9254  C  C   . ARG C 1 471 ? 307.338 246.002 244.332 1.00 24.82  ? 471 ARG C C   1 
ATOM   9255  O  O   . ARG C 1 471 ? 307.539 246.800 243.415 1.00 28.18  ? 471 ARG C O   1 
ATOM   9256  C  CB  . ARG C 1 471 ? 305.577 244.528 243.332 1.00 26.26  ? 471 ARG C CB  1 
ATOM   9257  C  CG  . ARG C 1 471 ? 305.776 243.044 243.570 1.00 31.45  ? 471 ARG C CG  1 
ATOM   9258  C  CD  . ARG C 1 471 ? 305.266 242.224 242.402 1.00 35.52  ? 471 ARG C CD  1 
ATOM   9259  N  NE  . ARG C 1 471 ? 305.884 242.623 241.145 1.00 42.67  ? 471 ARG C NE  1 
ATOM   9260  C  CZ  . ARG C 1 471 ? 306.744 241.876 240.468 1.00 54.44  ? 471 ARG C CZ  1 
ATOM   9261  N  NH1 . ARG C 1 471 ? 307.104 240.677 240.895 1.00 56.86  ? 471 ARG C NH1 1 
ATOM   9262  N  NH2 . ARG C 1 471 ? 307.255 242.343 239.332 1.00 55.16  ? 471 ARG C NH2 1 
ATOM   9263  N  N   . THR C 1 472 ? 308.286 245.622 245.182 1.00 31.14  ? 472 THR C N   1 
ATOM   9264  C  CA  . THR C 1 472 ? 309.652 246.091 245.004 1.00 28.58  ? 472 THR C CA  1 
ATOM   9265  C  C   . THR C 1 472 ? 310.159 245.681 243.629 1.00 33.98  ? 472 THR C C   1 
ATOM   9266  O  O   . THR C 1 472 ? 310.006 244.529 243.213 1.00 33.33  ? 472 THR C O   1 
ATOM   9267  C  CB  . THR C 1 472 ? 310.560 245.530 246.096 1.00 30.03  ? 472 THR C CB  1 
ATOM   9268  O  OG1 . THR C 1 472 ? 310.115 245.999 247.374 1.00 37.81  ? 472 THR C OG1 1 
ATOM   9269  C  CG2 . THR C 1 472 ? 311.992 245.981 245.876 1.00 23.30  ? 472 THR C CG2 1 
ATOM   9270  N  N   . SER C 1 473 ? 310.757 246.631 242.920 1.00 35.10  ? 473 SER C N   1 
ATOM   9271  C  CA  . SER C 1 473 ? 311.249 246.410 241.569 1.00 37.52  ? 473 SER C CA  1 
ATOM   9272  C  C   . SER C 1 473 ? 312.770 246.385 241.586 1.00 44.18  ? 473 SER C C   1 
ATOM   9273  O  O   . SER C 1 473 ? 313.405 247.323 242.079 1.00 48.23  ? 473 SER C O   1 
ATOM   9274  C  CB  . SER C 1 473 ? 310.741 247.497 240.619 1.00 31.79  ? 473 SER C CB  1 
ATOM   9275  O  OG  . SER C 1 473 ? 311.487 248.691 240.757 1.00 38.11  ? 473 SER C OG  1 
ATOM   9276  N  N   . ILE C 1 474 ? 313.347 245.311 241.051 1.00 45.60  ? 474 ILE C N   1 
ATOM   9277  C  CA  . ILE C 1 474 ? 314.799 245.187 240.936 1.00 57.53  ? 474 ILE C CA  1 
ATOM   9278  C  C   . ILE C 1 474 ? 315.207 245.901 239.650 1.00 60.39  ? 474 ILE C C   1 
ATOM   9279  O  O   . ILE C 1 474 ? 315.051 245.369 238.550 1.00 57.21  ? 474 ILE C O   1 
ATOM   9280  C  CB  . ILE C 1 474 ? 315.258 243.727 240.947 1.00 62.99  ? 474 ILE C CB  1 
ATOM   9281  C  CG1 . ILE C 1 474 ? 314.161 242.802 240.409 1.00 60.45  ? 474 ILE C CG1 1 
ATOM   9282  C  CG2 . ILE C 1 474 ? 315.677 243.309 242.352 1.00 50.99  ? 474 ILE C CG2 1 
ATOM   9283  C  CD1 . ILE C 1 474 ? 313.129 242.400 241.445 1.00 51.07  ? 474 ILE C CD1 1 
ATOM   9284  N  N   . ALA C 1 475 ? 315.732 247.115 239.790 1.00 62.53  ? 475 ALA C N   1 
ATOM   9285  C  CA  . ALA C 1 475 ? 316.105 247.951 238.662 1.00 61.66  ? 475 ALA C CA  1 
ATOM   9286  C  C   . ALA C 1 475 ? 317.515 248.479 238.870 1.00 66.57  ? 475 ALA C C   1 
ATOM   9287  O  O   . ALA C 1 475 ? 317.941 248.728 240.001 1.00 66.18  ? 475 ALA C O   1 
ATOM   9288  C  CB  . ALA C 1 475 ? 315.127 249.121 238.481 1.00 54.99  ? 475 ALA C CB  1 
ATOM   9289  N  N   . PHE C 1 476 ? 318.236 248.649 237.768 1.00 65.79  ? 476 PHE C N   1 
ATOM   9290  C  CA  . PHE C 1 476 ? 319.630 249.064 237.834 1.00 64.68  ? 476 PHE C CA  1 
ATOM   9291  C  C   . PHE C 1 476 ? 319.894 250.272 236.942 1.00 65.59  ? 476 PHE C C   1 
ATOM   9292  O  O   . PHE C 1 476 ? 320.091 251.384 237.432 1.00 64.86  ? 476 PHE C O   1 
ATOM   9293  C  CB  . PHE C 1 476 ? 320.543 247.902 237.442 1.00 59.45  ? 476 PHE C CB  1 
ATOM   9294  C  CG  . PHE C 1 476 ? 320.099 246.577 237.991 1.00 60.16  ? 476 PHE C CG  1 
ATOM   9295  C  CD1 . PHE C 1 476 ? 320.542 246.140 239.227 1.00 59.94  ? 476 PHE C CD1 1 
ATOM   9296  C  CD2 . PHE C 1 476 ? 319.230 245.772 237.274 1.00 56.50  ? 476 PHE C CD2 1 
ATOM   9297  C  CE1 . PHE C 1 476 ? 320.130 244.925 239.736 1.00 58.97  ? 476 PHE C CE1 1 
ATOM   9298  C  CE2 . PHE C 1 476 ? 318.816 244.556 237.777 1.00 59.66  ? 476 PHE C CE2 1 
ATOM   9299  C  CZ  . PHE C 1 476 ? 319.266 244.132 239.010 1.00 57.74  ? 476 PHE C CZ  1 
ATOM   9300  N  N   . THR D 2 49  ? 303.580 240.244 281.700 1.00 56.60  ? 47  THR D N   1 
ATOM   9301  C  CA  . THR D 2 49  ? 302.482 241.096 281.259 1.00 66.09  ? 47  THR D CA  1 
ATOM   9302  C  C   . THR D 2 49  ? 302.596 241.394 279.768 1.00 64.60  ? 47  THR D C   1 
ATOM   9303  O  O   . THR D 2 49  ? 301.670 241.133 279.001 1.00 63.46  ? 47  THR D O   1 
ATOM   9304  C  CB  . THR D 2 49  ? 302.456 242.409 282.063 1.00 30.00  ? 47  THR D CB  1 
ATOM   9305  O  OG1 . THR D 2 49  ? 303.700 243.098 281.899 1.00 30.00  ? 47  THR D OG1 1 
ATOM   9306  C  CG2 . THR D 2 49  ? 302.410 242.119 283.556 1.00 30.00  ? 47  THR D CG2 1 
ATOM   9307  N  N   . LEU D 2 50  ? 303.737 241.945 279.365 1.00 55.42  ? 48  LEU D N   1 
ATOM   9308  C  CA  . LEU D 2 50  ? 303.991 242.195 277.955 1.00 48.40  ? 48  LEU D CA  1 
ATOM   9309  C  C   . LEU D 2 50  ? 304.200 240.886 277.204 1.00 46.32  ? 48  LEU D C   1 
ATOM   9310  O  O   . LEU D 2 50  ? 304.766 239.924 277.729 1.00 48.82  ? 48  LEU D O   1 
ATOM   9311  C  CB  . LEU D 2 50  ? 305.216 243.092 277.783 1.00 47.07  ? 48  LEU D CB  1 
ATOM   9312  C  CG  . LEU D 2 50  ? 304.973 244.504 277.253 1.00 46.52  ? 48  LEU D CG  1 
ATOM   9313  C  CD1 . LEU D 2 50  ? 303.979 245.243 278.129 1.00 48.66  ? 48  LEU D CD1 1 
ATOM   9314  C  CD2 . LEU D 2 50  ? 306.283 245.266 277.165 1.00 45.84  ? 48  LEU D CD2 1 
ATOM   9315  N  N   . SER D 2 51  ? 303.731 240.856 275.962 1.00 42.65  ? 49  SER D N   1 
ATOM   9316  C  CA  . SER D 2 51  ? 303.956 239.703 275.108 1.00 38.99  ? 49  SER D CA  1 
ATOM   9317  C  C   . SER D 2 51  ? 305.371 239.738 274.534 1.00 38.13  ? 49  SER D C   1 
ATOM   9318  O  O   . SER D 2 51  ? 306.067 240.755 274.579 1.00 41.29  ? 49  SER D O   1 
ATOM   9319  C  CB  . SER D 2 51  ? 302.919 239.656 273.986 1.00 34.77  ? 49  SER D CB  1 
ATOM   9320  O  OG  . SER D 2 51  ? 303.126 240.697 273.050 1.00 37.65  ? 49  SER D OG  1 
ATOM   9321  N  N   . ASN D 2 52  ? 305.799 238.597 273.993 1.00 32.64  ? 50  ASN D N   1 
ATOM   9322  C  CA  . ASN D 2 52  ? 307.122 238.520 273.382 1.00 29.45  ? 50  ASN D CA  1 
ATOM   9323  C  C   . ASN D 2 52  ? 307.228 239.458 272.187 1.00 33.73  ? 50  ASN D C   1 
ATOM   9324  O  O   . ASN D 2 52  ? 308.256 240.120 271.993 1.00 35.93  ? 50  ASN D O   1 
ATOM   9325  C  CB  . ASN D 2 52  ? 307.419 237.079 272.968 1.00 30.66  ? 50  ASN D CB  1 
ATOM   9326  C  CG  . ASN D 2 52  ? 308.874 236.862 272.611 1.00 30.26  ? 50  ASN D CG  1 
ATOM   9327  O  OD1 . ASN D 2 52  ? 309.232 236.779 271.437 1.00 28.70  ? 50  ASN D OD1 1 
ATOM   9328  N  ND2 . ASN D 2 52  ? 309.723 236.766 273.625 1.00 38.84  ? 50  ASN D ND2 1 
ATOM   9329  N  N   . ARG D 2 53  ? 306.171 239.528 271.376 1.00 32.84  ? 51  ARG D N   1 
ATOM   9330  C  CA  . ARG D 2 53  ? 306.159 240.444 270.240 1.00 29.68  ? 51  ARG D CA  1 
ATOM   9331  C  C   . ARG D 2 53  ? 306.338 241.884 270.702 1.00 35.46  ? 51  ARG D C   1 
ATOM   9332  O  O   . ARG D 2 53  ? 307.114 242.647 270.114 1.00 40.39  ? 51  ARG D O   1 
ATOM   9333  C  CB  . ARG D 2 53  ? 304.849 240.290 269.466 1.00 26.04  ? 51  ARG D CB  1 
ATOM   9334  C  CG  . ARG D 2 53  ? 304.672 238.951 268.776 1.00 25.45  ? 51  ARG D CG  1 
ATOM   9335  C  CD  . ARG D 2 53  ? 305.446 238.881 267.479 1.00 25.96  ? 51  ARG D CD  1 
ATOM   9336  N  NE  . ARG D 2 53  ? 304.819 237.964 266.536 1.00 25.07  ? 51  ARG D NE  1 
ATOM   9337  C  CZ  . ARG D 2 53  ? 305.418 237.469 265.463 1.00 26.67  ? 51  ARG D CZ  1 
ATOM   9338  N  NH1 . ARG D 2 53  ? 306.667 237.782 265.163 1.00 26.07  ? 51  ARG D NH1 1 
ATOM   9339  N  NH2 . ARG D 2 53  ? 304.745 236.642 264.668 1.00 28.59  ? 51  ARG D NH2 1 
ATOM   9340  N  N   . ALA D 2 54  ? 305.621 242.273 271.758 1.00 30.78  ? 52  ALA D N   1 
ATOM   9341  C  CA  . ALA D 2 54  ? 305.728 243.637 272.263 1.00 28.66  ? 52  ALA D CA  1 
ATOM   9342  C  C   . ALA D 2 54  ? 307.123 243.917 272.803 1.00 32.67  ? 52  ALA D C   1 
ATOM   9343  O  O   . ALA D 2 54  ? 307.663 245.009 272.604 1.00 39.36  ? 52  ALA D O   1 
ATOM   9344  C  CB  . ALA D 2 54  ? 304.676 243.885 273.342 1.00 29.99  ? 52  ALA D CB  1 
ATOM   9345  N  N   . GLN D 2 55  ? 307.718 242.949 273.501 1.00 33.99  ? 53  GLN D N   1 
ATOM   9346  C  CA  . GLN D 2 55  ? 309.069 243.139 274.017 1.00 34.57  ? 53  GLN D CA  1 
ATOM   9347  C  C   . GLN D 2 55  ? 310.063 243.335 272.880 1.00 33.29  ? 53  GLN D C   1 
ATOM   9348  O  O   . GLN D 2 55  ? 310.913 244.233 272.926 1.00 37.37  ? 53  GLN D O   1 
ATOM   9349  C  CB  . GLN D 2 55  ? 309.470 241.948 274.886 1.00 36.79  ? 53  GLN D CB  1 
ATOM   9350  C  CG  . GLN D 2 55  ? 308.707 241.856 276.196 1.00 37.14  ? 53  GLN D CG  1 
ATOM   9351  C  CD  . GLN D 2 55  ? 308.897 240.523 276.887 1.00 43.33  ? 53  GLN D CD  1 
ATOM   9352  O  OE1 . GLN D 2 55  ? 309.921 239.864 276.719 1.00 49.08  ? 53  GLN D OE1 1 
ATOM   9353  N  NE2 . GLN D 2 55  ? 307.903 240.114 277.667 1.00 40.64  ? 53  GLN D NE2 1 
ATOM   9354  N  N   . GLU D 2 56  ? 309.967 242.500 271.843 1.00 33.63  ? 54  GLU D N   1 
ATOM   9355  C  CA  . GLU D 2 56  ? 310.865 242.642 270.702 1.00 37.67  ? 54  GLU D CA  1 
ATOM   9356  C  C   . GLU D 2 56  ? 310.679 243.993 270.023 1.00 40.08  ? 54  GLU D C   1 
ATOM   9357  O  O   . GLU D 2 56  ? 311.658 244.676 269.696 1.00 44.78  ? 54  GLU D O   1 
ATOM   9358  C  CB  . GLU D 2 56  ? 310.631 241.500 269.714 1.00 39.04  ? 54  GLU D CB  1 
ATOM   9359  C  CG  . GLU D 2 56  ? 311.846 241.125 268.886 1.00 47.69  ? 54  GLU D CG  1 
ATOM   9360  C  CD  . GLU D 2 56  ? 311.918 241.886 267.578 1.00 54.70  ? 54  GLU D CD  1 
ATOM   9361  O  OE1 . GLU D 2 56  ? 310.855 242.294 267.066 1.00 56.14  ? 54  GLU D OE1 1 
ATOM   9362  O  OE2 . GLU D 2 56  ? 313.038 242.075 267.060 1.00 57.24  ? 54  GLU D OE2 1 
ATOM   9363  N  N   . PHE D 2 57  ? 309.426 244.407 269.820 1.00 37.25  ? 55  PHE D N   1 
ATOM   9364  C  CA  . PHE D 2 57  ? 309.159 245.693 269.186 1.00 35.59  ? 55  PHE D CA  1 
ATOM   9365  C  C   . PHE D 2 57  ? 309.723 246.843 270.014 1.00 37.50  ? 55  PHE D C   1 
ATOM   9366  O  O   . PHE D 2 57  ? 310.355 247.761 269.479 1.00 42.20  ? 55  PHE D O   1 
ATOM   9367  C  CB  . PHE D 2 57  ? 307.654 245.860 268.978 1.00 36.30  ? 55  PHE D CB  1 
ATOM   9368  C  CG  . PHE D 2 57  ? 307.286 247.009 268.089 1.00 38.48  ? 55  PHE D CG  1 
ATOM   9369  C  CD1 . PHE D 2 57  ? 307.636 247.008 266.752 1.00 39.56  ? 55  PHE D CD1 1 
ATOM   9370  C  CD2 . PHE D 2 57  ? 306.578 248.086 268.590 1.00 33.19  ? 55  PHE D CD2 1 
ATOM   9371  C  CE1 . PHE D 2 57  ? 307.293 248.063 265.933 1.00 35.79  ? 55  PHE D CE1 1 
ATOM   9372  C  CE2 . PHE D 2 57  ? 306.233 249.141 267.776 1.00 32.48  ? 55  PHE D CE2 1 
ATOM   9373  C  CZ  . PHE D 2 57  ? 306.591 249.130 266.446 1.00 35.53  ? 55  PHE D CZ  1 
ATOM   9374  N  N   . ASN D 2 58  ? 309.501 246.809 271.330 1.00 37.77  ? 56  ASN D N   1 
ATOM   9375  C  CA  . ASN D 2 58  ? 309.994 247.875 272.193 1.00 36.94  ? 56  ASN D CA  1 
ATOM   9376  C  C   . ASN D 2 58  ? 311.513 247.942 272.172 1.00 39.79  ? 56  ASN D C   1 
ATOM   9377  O  O   . ASN D 2 58  ? 312.092 249.031 272.093 1.00 42.96  ? 56  ASN D O   1 
ATOM   9378  C  CB  . ASN D 2 58  ? 309.487 247.672 273.620 1.00 38.14  ? 56  ASN D CB  1 
ATOM   9379  C  CG  . ASN D 2 58  ? 308.061 248.146 273.803 1.00 47.27  ? 56  ASN D CG  1 
ATOM   9380  O  OD1 . ASN D 2 58  ? 307.603 249.056 273.113 1.00 51.39  ? 56  ASN D OD1 1 
ATOM   9381  N  ND2 . ASN D 2 58  ? 307.347 247.525 274.734 1.00 49.59  ? 56  ASN D ND2 1 
ATOM   9382  N  N   . ARG D 2 59  ? 312.180 246.789 272.244 1.00 39.89  ? 57  ARG D N   1 
ATOM   9383  C  CA  . ARG D 2 59  ? 313.637 246.802 272.203 1.00 37.80  ? 57  ARG D CA  1 
ATOM   9384  C  C   . ARG D 2 59  ? 314.149 247.252 270.843 1.00 39.80  ? 57  ARG D C   1 
ATOM   9385  O  O   . ARG D 2 59  ? 315.262 247.781 270.746 1.00 45.55  ? 57  ARG D O   1 
ATOM   9386  C  CB  . ARG D 2 59  ? 314.187 245.424 272.567 1.00 36.17  ? 57  ARG D CB  1 
ATOM   9387  C  CG  . ARG D 2 59  ? 314.676 244.605 271.393 1.00 44.05  ? 57  ARG D CG  1 
ATOM   9388  C  CD  . ARG D 2 59  ? 315.542 243.458 271.879 1.00 44.90  ? 57  ARG D CD  1 
ATOM   9389  N  NE  . ARG D 2 59  ? 314.983 242.836 273.072 1.00 43.25  ? 57  ARG D NE  1 
ATOM   9390  C  CZ  . ARG D 2 59  ? 314.220 241.752 273.067 1.00 47.11  ? 57  ARG D CZ  1 
ATOM   9391  N  NH1 . ARG D 2 59  ? 313.910 241.130 271.942 1.00 42.52  ? 57  ARG D NH1 1 
ATOM   9392  N  NH2 . ARG D 2 59  ? 313.757 241.280 274.221 1.00 45.94  ? 57  ARG D NH2 1 
ATOM   9393  N  N   . ARG D 2 60  ? 313.359 247.056 269.788 1.00 41.84  ? 58  ARG D N   1 
ATOM   9394  C  CA  . ARG D 2 60  ? 313.707 247.614 268.488 1.00 39.38  ? 58  ARG D CA  1 
ATOM   9395  C  C   . ARG D 2 60  ? 313.454 249.115 268.410 1.00 42.44  ? 58  ARG D C   1 
ATOM   9396  O  O   . ARG D 2 60  ? 314.062 249.790 267.573 1.00 45.00  ? 58  ARG D O   1 
ATOM   9397  C  CB  . ARG D 2 60  ? 312.924 246.897 267.386 1.00 39.22  ? 58  ARG D CB  1 
ATOM   9398  C  CG  . ARG D 2 60  ? 312.933 247.610 266.047 1.00 41.27  ? 58  ARG D CG  1 
ATOM   9399  C  CD  . ARG D 2 60  ? 312.704 246.642 264.900 1.00 34.72  ? 58  ARG D CD  1 
ATOM   9400  N  NE  . ARG D 2 60  ? 311.783 245.572 265.264 1.00 43.25  ? 58  ARG D NE  1 
ATOM   9401  C  CZ  . ARG D 2 60  ? 310.503 245.536 264.918 1.00 46.65  ? 58  ARG D CZ  1 
ATOM   9402  N  NH1 . ARG D 2 60  ? 309.953 246.501 264.199 1.00 39.88  ? 58  ARG D NH1 1 
ATOM   9403  N  NH2 . ARG D 2 60  ? 309.756 244.506 265.305 1.00 44.98  ? 58  ARG D NH2 1 
ATOM   9404  N  N   . LEU D 2 61  ? 312.578 249.651 269.263 1.00 44.69  ? 59  LEU D N   1 
ATOM   9405  C  CA  . LEU D 2 61  ? 312.244 251.072 269.258 1.00 39.39  ? 59  LEU D CA  1 
ATOM   9406  C  C   . LEU D 2 61  ? 313.059 251.880 270.263 1.00 42.77  ? 59  LEU D C   1 
ATOM   9407  O  O   . LEU D 2 61  ? 312.600 252.934 270.721 1.00 46.48  ? 59  LEU D O   1 
ATOM   9408  C  CB  . LEU D 2 61  ? 310.750 251.261 269.521 1.00 38.25  ? 59  LEU D CB  1 
ATOM   9409  C  CG  . LEU D 2 61  ? 309.816 251.073 268.327 1.00 40.68  ? 59  LEU D CG  1 
ATOM   9410  C  CD1 . LEU D 2 61  ? 308.394 251.442 268.711 1.00 37.20  ? 59  LEU D CD1 1 
ATOM   9411  C  CD2 . LEU D 2 61  ? 310.285 251.893 267.138 1.00 39.46  ? 59  LEU D CD2 1 
ATOM   9412  N  N   . THR D 2 62  ? 314.250 251.417 270.625 1.00 47.85  ? 60  THR D N   1 
ATOM   9413  C  CA  . THR D 2 62  ? 315.116 252.136 271.547 1.00 48.94  ? 60  THR D CA  1 
ATOM   9414  C  C   . THR D 2 62  ? 316.254 252.798 270.781 1.00 50.90  ? 60  THR D C   1 
ATOM   9415  O  O   . THR D 2 62  ? 316.812 252.213 269.849 1.00 51.23  ? 60  THR D O   1 
ATOM   9416  C  CB  . THR D 2 62  ? 315.684 251.200 272.616 1.00 51.55  ? 60  THR D CB  1 
ATOM   9417  O  OG1 . THR D 2 62  ? 316.791 250.470 272.075 1.00 56.50  ? 60  THR D OG1 1 
ATOM   9418  C  CG2 . THR D 2 62  ? 314.621 250.221 273.086 1.00 44.76  ? 60  THR D CG2 1 
ATOM   9419  N  N   . GLN D 2 63  ? 316.592 254.021 271.180 1.00 47.83  ? 61  GLN D N   1 
ATOM   9420  C  CA  . GLN D 2 63  ? 317.662 254.763 270.528 1.00 46.90  ? 61  GLN D CA  1 
ATOM   9421  C  C   . GLN D 2 63  ? 319.015 254.334 271.080 1.00 48.83  ? 61  GLN D C   1 
ATOM   9422  O  O   . GLN D 2 63  ? 319.200 254.248 272.297 1.00 52.28  ? 61  GLN D O   1 
ATOM   9423  C  CB  . GLN D 2 63  ? 317.465 256.265 270.721 1.00 41.47  ? 61  GLN D CB  1 
ATOM   9424  C  CG  . GLN D 2 63  ? 316.018 256.700 270.783 1.00 33.37  ? 61  GLN D CG  1 
ATOM   9425  C  CD  . GLN D 2 63  ? 315.868 258.204 270.801 1.00 33.82  ? 61  GLN D CD  1 
ATOM   9426  O  OE1 . GLN D 2 63  ? 316.435 258.905 269.965 1.00 34.21  ? 61  GLN D OE1 1 
ATOM   9427  N  NE2 . GLN D 2 63  ? 315.101 258.710 271.757 1.00 33.48  ? 61  GLN D NE2 1 
ATOM   9428  N  N   . LYS D 2 64  ? 319.960 254.072 270.183 1.00 54.60  ? 62  LYS D N   1 
ATOM   9429  C  CA  . LYS D 2 64  ? 321.309 253.665 270.548 1.00 56.23  ? 62  LYS D CA  1 
ATOM   9430  C  C   . LYS D 2 64  ? 322.301 254.729 270.099 1.00 56.29  ? 62  LYS D C   1 
ATOM   9431  O  O   . LYS D 2 64  ? 322.307 255.123 268.928 1.00 60.18  ? 62  LYS D O   1 
ATOM   9432  C  CB  . LYS D 2 64  ? 321.662 252.314 269.923 1.00 61.29  ? 62  LYS D CB  1 
ATOM   9433  C  CG  . LYS D 2 64  ? 321.590 251.146 270.892 1.00 64.54  ? 62  LYS D CG  1 
ATOM   9434  C  CD  . LYS D 2 64  ? 320.167 250.634 271.047 1.00 62.54  ? 62  LYS D CD  1 
ATOM   9435  C  CE  . LYS D 2 64  ? 319.666 250.001 269.758 1.00 62.40  ? 62  LYS D CE  1 
ATOM   9436  N  NZ  . LYS D 2 64  ? 318.194 249.781 269.781 1.00 55.42  ? 62  LYS D NZ  1 
ATOM   9437  N  N   . THR D 2 65  ? 323.137 255.186 271.030 1.00 51.11  ? 63  THR D N   1 
ATOM   9438  C  CA  . THR D 2 65  ? 324.143 256.208 270.764 1.00 47.82  ? 63  THR D CA  1 
ATOM   9439  C  C   . THR D 2 65  ? 325.546 255.696 271.073 1.00 52.07  ? 63  THR D C   1 
ATOM   9440  O  O   . THR D 2 65  ? 326.445 256.476 271.390 1.00 53.69  ? 63  THR D O   1 
ATOM   9441  C  CB  . THR D 2 65  ? 323.849 257.474 271.568 1.00 46.04  ? 63  THR D CB  1 
ATOM   9442  O  OG1 . THR D 2 65  ? 324.431 257.360 272.872 1.00 51.15  ? 63  THR D OG1 1 
ATOM   9443  C  CG2 . THR D 2 65  ? 322.349 257.673 271.715 1.00 41.64  ? 63  THR D CG2 1 
ATOM   9444  N  N   . ASP D 2 66  ? 325.743 254.382 270.979 1.00 57.68  ? 64  ASP D N   1 
ATOM   9445  C  CA  . ASP D 2 66  ? 326.978 253.744 271.422 1.00 60.62  ? 64  ASP D CA  1 
ATOM   9446  C  C   . ASP D 2 66  ? 328.213 254.206 270.653 1.00 61.29  ? 64  ASP D C   1 
ATOM   9447  O  O   . ASP D 2 66  ? 329.210 254.602 271.264 1.00 61.17  ? 64  ASP D O   1 
ATOM   9448  C  CB  . ASP D 2 66  ? 326.841 252.220 271.335 1.00 64.55  ? 64  ASP D CB  1 
ATOM   9449  C  CG  . ASP D 2 66  ? 326.405 251.740 269.958 1.00 72.34  ? 64  ASP D CG  1 
ATOM   9450  O  OD1 . ASP D 2 66  ? 326.145 252.580 269.073 1.00 68.39  ? 64  ASP D OD1 1 
ATOM   9451  O  OD2 . ASP D 2 66  ? 326.328 250.508 269.760 1.00 75.30  ? 64  ASP D OD2 1 
ATOM   9452  N  N   . ASN D 2 67  ? 328.169 254.161 269.325 1.00 51.94  ? 65  ASN D N   1 
ATOM   9453  C  CA  . ASN D 2 67  ? 329.348 254.458 268.512 1.00 45.89  ? 65  ASN D CA  1 
ATOM   9454  C  C   . ASN D 2 67  ? 329.174 255.739 267.702 1.00 43.44  ? 65  ASN D C   1 
ATOM   9455  O  O   . ASN D 2 67  ? 329.692 255.871 266.595 1.00 46.21  ? 65  ASN D O   1 
ATOM   9456  C  CB  . ASN D 2 67  ? 329.660 253.277 267.601 1.00 54.59  ? 65  ASN D CB  1 
ATOM   9457  C  CG  . ASN D 2 67  ? 330.134 252.060 268.368 1.00 65.26  ? 65  ASN D CG  1 
ATOM   9458  O  OD1 . ASN D 2 67  ? 329.350 251.160 268.670 1.00 64.63  ? 65  ASN D OD1 1 
ATOM   9459  N  ND2 . ASN D 2 67  ? 331.421 252.027 268.690 1.00 64.38  ? 65  ASN D ND2 1 
ATOM   9460  N  N   . ALA D 2 68  ? 328.439 256.695 268.252 1.00 42.83  ? 66  ALA D N   1 
ATOM   9461  C  CA  . ALA D 2 68  ? 328.214 257.957 267.563 1.00 33.35  ? 66  ALA D CA  1 
ATOM   9462  C  C   . ALA D 2 68  ? 329.530 258.711 267.411 1.00 30.82  ? 66  ALA D C   1 
ATOM   9463  O  O   . ALA D 2 68  ? 330.254 258.876 268.399 1.00 32.59  ? 66  ALA D O   1 
ATOM   9464  C  CB  . ALA D 2 68  ? 327.207 258.807 268.325 1.00 33.43  ? 66  ALA D CB  1 
ATOM   9465  N  N   . PRO D 2 69  ? 329.880 259.175 266.208 1.00 31.05  ? 67  PRO D N   1 
ATOM   9466  C  CA  . PRO D 2 69  ? 331.103 259.981 266.063 1.00 25.03  ? 67  PRO D CA  1 
ATOM   9467  C  C   . PRO D 2 69  ? 330.988 261.366 266.668 1.00 26.05  ? 67  PRO D C   1 
ATOM   9468  O  O   . PRO D 2 69  ? 332.016 262.023 266.868 1.00 27.31  ? 67  PRO D O   1 
ATOM   9469  C  CB  . PRO D 2 69  ? 331.306 260.056 264.541 1.00 24.91  ? 67  PRO D CB  1 
ATOM   9470  C  CG  . PRO D 2 69  ? 330.329 259.091 263.943 1.00 27.60  ? 67  PRO D CG  1 
ATOM   9471  C  CD  . PRO D 2 69  ? 329.214 258.940 264.918 1.00 27.07  ? 67  PRO D CD  1 
ATOM   9472  N  N   . TRP D 2 70  ? 329.776 261.834 266.958 1.00 24.30  ? 68  TRP D N   1 
ATOM   9473  C  CA  . TRP D 2 70  ? 329.555 263.164 267.502 1.00 20.75  ? 68  TRP D CA  1 
ATOM   9474  C  C   . TRP D 2 70  ? 328.465 263.093 268.560 1.00 22.94  ? 68  TRP D C   1 
ATOM   9475  O  O   . TRP D 2 70  ? 327.479 262.370 268.397 1.00 25.29  ? 68  TRP D O   1 
ATOM   9476  C  CB  . TRP D 2 70  ? 329.175 264.152 266.392 1.00 16.71  ? 68  TRP D CB  1 
ATOM   9477  C  CG  . TRP D 2 70  ? 328.809 265.515 266.879 1.00 14.40  ? 68  TRP D CG  1 
ATOM   9478  C  CD1 . TRP D 2 70  ? 329.656 266.551 267.128 1.00 12.04  ? 68  TRP D CD1 1 
ATOM   9479  C  CD2 . TRP D 2 70  ? 327.492 265.997 267.164 1.00 15.28  ? 68  TRP D CD2 1 
ATOM   9480  N  NE1 . TRP D 2 70  ? 328.951 267.645 267.560 1.00 12.68  ? 68  TRP D NE1 1 
ATOM   9481  C  CE2 . TRP D 2 70  ? 327.619 267.331 267.591 1.00 12.11  ? 68  TRP D CE2 1 
ATOM   9482  C  CE3 . TRP D 2 70  ? 326.219 265.426 267.104 1.00 15.08  ? 68  TRP D CE3 1 
ATOM   9483  C  CZ2 . TRP D 2 70  ? 326.521 268.105 267.950 1.00 12.60  ? 68  TRP D CZ2 1 
ATOM   9484  C  CZ3 . TRP D 2 70  ? 325.133 266.194 267.464 1.00 15.24  ? 68  TRP D CZ3 1 
ATOM   9485  C  CH2 . TRP D 2 70  ? 325.289 267.519 267.880 1.00 15.94  ? 68  TRP D CH2 1 
ATOM   9486  N  N   . ARG D 2 71  ? 328.652 263.841 269.646 1.00 21.47  ? 69  ARG D N   1 
ATOM   9487  C  CA  . ARG D 2 71  ? 327.714 263.835 270.758 1.00 19.85  ? 69  ARG D CA  1 
ATOM   9488  C  C   . ARG D 2 71  ? 327.715 265.202 271.422 1.00 22.11  ? 69  ARG D C   1 
ATOM   9489  O  O   . ARG D 2 71  ? 328.701 265.940 271.352 1.00 23.69  ? 69  ARG D O   1 
ATOM   9490  C  CB  . ARG D 2 71  ? 328.069 262.761 271.794 1.00 25.58  ? 69  ARG D CB  1 
ATOM   9491  C  CG  . ARG D 2 71  ? 327.541 261.378 271.484 1.00 30.97  ? 69  ARG D CG  1 
ATOM   9492  C  CD  . ARG D 2 71  ? 327.626 260.479 272.705 1.00 38.28  ? 69  ARG D CD  1 
ATOM   9493  N  NE  . ARG D 2 71  ? 328.544 261.002 273.710 1.00 42.03  ? 69  ARG D NE  1 
ATOM   9494  C  CZ  . ARG D 2 71  ? 328.199 261.307 274.953 1.00 44.93  ? 69  ARG D CZ  1 
ATOM   9495  N  NH1 . ARG D 2 71  ? 326.957 261.159 275.382 1.00 41.30  ? 69  ARG D NH1 1 
ATOM   9496  N  NH2 . ARG D 2 71  ? 329.124 261.768 275.790 1.00 45.48  ? 69  ARG D NH2 1 
ATOM   9497  N  N   . ARG D 2 72  ? 326.604 265.528 272.077 1.00 22.57  ? 70  ARG D N   1 
ATOM   9498  C  CA  . ARG D 2 72  ? 326.518 266.774 272.838 1.00 19.50  ? 70  ARG D CA  1 
ATOM   9499  C  C   . ARG D 2 72  ? 325.394 266.660 273.854 1.00 21.46  ? 70  ARG D C   1 
ATOM   9500  O  O   . ARG D 2 72  ? 324.246 266.417 273.478 1.00 26.72  ? 70  ARG D O   1 
ATOM   9501  C  CB  . ARG D 2 72  ? 326.294 267.965 271.911 1.00 18.49  ? 70  ARG D CB  1 
ATOM   9502  C  CG  . ARG D 2 72  ? 327.571 268.674 271.508 1.00 16.64  ? 70  ARG D CG  1 
ATOM   9503  C  CD  . ARG D 2 72  ? 327.300 270.106 271.108 1.00 20.67  ? 70  ARG D CD  1 
ATOM   9504  N  NE  . ARG D 2 72  ? 327.609 271.044 272.179 1.00 23.74  ? 70  ARG D NE  1 
ATOM   9505  C  CZ  . ARG D 2 72  ? 327.619 272.361 272.037 1.00 23.56  ? 70  ARG D CZ  1 
ATOM   9506  N  NH1 . ARG D 2 72  ? 327.340 272.932 270.878 1.00 27.06  ? 70  ARG D NH1 1 
ATOM   9507  N  NH2 . ARG D 2 72  ? 327.918 273.124 273.083 1.00 21.91  ? 70  ARG D NH2 1 
ATOM   9508  N  N   . VAL D 2 73  ? 325.715 266.852 275.130 1.00 20.66  ? 71  VAL D N   1 
ATOM   9509  C  CA  . VAL D 2 73  ? 324.734 266.800 276.208 1.00 25.08  ? 71  VAL D CA  1 
ATOM   9510  C  C   . VAL D 2 73  ? 324.313 268.220 276.554 1.00 27.18  ? 71  VAL D C   1 
ATOM   9511  O  O   . VAL D 2 73  ? 325.162 269.105 276.723 1.00 32.08  ? 71  VAL D O   1 
ATOM   9512  C  CB  . VAL D 2 73  ? 325.297 266.073 277.440 1.00 26.11  ? 71  VAL D CB  1 
ATOM   9513  C  CG1 . VAL D 2 73  ? 324.373 266.264 278.632 1.00 26.45  ? 71  VAL D CG1 1 
ATOM   9514  C  CG2 . VAL D 2 73  ? 325.489 264.599 277.139 1.00 25.79  ? 71  VAL D CG2 1 
ATOM   9515  N  N   . VAL D 2 74  ? 323.005 268.440 276.658 1.00 24.69  ? 72  VAL D N   1 
ATOM   9516  C  CA  . VAL D 2 74  ? 322.436 269.756 276.923 1.00 25.53  ? 72  VAL D CA  1 
ATOM   9517  C  C   . VAL D 2 74  ? 321.392 269.630 278.025 1.00 28.05  ? 72  VAL D C   1 
ATOM   9518  O  O   . VAL D 2 74  ? 320.498 268.781 277.945 1.00 31.60  ? 72  VAL D O   1 
ATOM   9519  C  CB  . VAL D 2 74  ? 321.810 270.366 275.654 1.00 29.81  ? 72  VAL D CB  1 
ATOM   9520  C  CG1 . VAL D 2 74  ? 321.282 271.758 275.939 1.00 30.57  ? 72  VAL D CG1 1 
ATOM   9521  C  CG2 . VAL D 2 74  ? 322.829 270.402 274.527 1.00 31.72  ? 72  VAL D CG2 1 
ATOM   9522  N  N   . TYR D 2 75  ? 321.494 270.481 279.043 1.00 29.72  ? 73  TYR D N   1 
ATOM   9523  C  CA  . TYR D 2 75  ? 320.524 270.547 280.127 1.00 27.38  ? 73  TYR D CA  1 
ATOM   9524  C  C   . TYR D 2 75  ? 319.630 271.757 279.896 1.00 27.84  ? 73  TYR D C   1 
ATOM   9525  O  O   . TYR D 2 75  ? 320.105 272.899 279.955 1.00 32.95  ? 73  TYR D O   1 
ATOM   9526  C  CB  . TYR D 2 75  ? 321.212 270.662 281.487 1.00 26.65  ? 73  TYR D CB  1 
ATOM   9527  C  CG  . TYR D 2 75  ? 322.193 269.562 281.808 1.00 28.28  ? 73  TYR D CG  1 
ATOM   9528  C  CD1 . TYR D 2 75  ? 323.415 269.481 281.156 1.00 28.54  ? 73  TYR D CD1 1 
ATOM   9529  C  CD2 . TYR D 2 75  ? 321.910 268.621 282.786 1.00 29.88  ? 73  TYR D CD2 1 
ATOM   9530  C  CE1 . TYR D 2 75  ? 324.316 268.484 281.454 1.00 28.43  ? 73  TYR D CE1 1 
ATOM   9531  C  CE2 . TYR D 2 75  ? 322.807 267.621 283.093 1.00 31.97  ? 73  TYR D CE2 1 
ATOM   9532  C  CZ  . TYR D 2 75  ? 324.009 267.557 282.424 1.00 34.01  ? 73  TYR D CZ  1 
ATOM   9533  O  OH  . TYR D 2 75  ? 324.906 266.560 282.727 1.00 38.03  ? 73  TYR D OH  1 
ATOM   9534  N  N   . ARG D 2 76  ? 318.346 271.500 279.662 1.00 26.16  ? 74  ARG D N   1 
ATOM   9535  C  CA  . ARG D 2 76  ? 317.346 272.510 279.354 1.00 27.71  ? 74  ARG D CA  1 
ATOM   9536  C  C   . ARG D 2 76  ? 316.361 272.651 280.506 1.00 26.85  ? 74  ARG D C   1 
ATOM   9537  O  O   . ARG D 2 76  ? 316.049 271.680 281.201 1.00 30.30  ? 74  ARG D O   1 
ATOM   9538  C  CB  . ARG D 2 76  ? 316.568 272.146 278.087 1.00 29.48  ? 74  ARG D CB  1 
ATOM   9539  C  CG  . ARG D 2 76  ? 317.323 272.293 276.786 1.00 30.56  ? 74  ARG D CG  1 
ATOM   9540  C  CD  . ARG D 2 76  ? 316.377 272.056 275.622 1.00 30.51  ? 74  ARG D CD  1 
ATOM   9541  N  NE  . ARG D 2 76  ? 317.075 271.946 274.348 1.00 35.85  ? 74  ARG D NE  1 
ATOM   9542  C  CZ  . ARG D 2 76  ? 317.392 272.976 273.577 1.00 38.24  ? 74  ARG D CZ  1 
ATOM   9543  N  NH1 . ARG D 2 76  ? 317.066 274.214 273.910 1.00 35.59  ? 74  ARG D NH1 1 
ATOM   9544  N  NH2 . ARG D 2 76  ? 318.047 272.758 272.440 1.00 36.95  ? 74  ARG D NH2 1 
ATOM   9545  N  N   . ARG D 2 77  ? 315.863 273.869 280.691 1.00 28.73  ? 75  ARG D N   1 
ATOM   9546  C  CA  . ARG D 2 77  ? 314.803 274.153 281.649 1.00 28.49  ? 75  ARG D CA  1 
ATOM   9547  C  C   . ARG D 2 77  ? 313.504 274.368 280.885 1.00 30.81  ? 75  ARG D C   1 
ATOM   9548  O  O   . ARG D 2 77  ? 313.399 275.299 280.080 1.00 32.26  ? 75  ARG D O   1 
ATOM   9549  C  CB  . ARG D 2 77  ? 315.140 275.378 282.498 1.00 31.24  ? 75  ARG D CB  1 
ATOM   9550  C  CG  . ARG D 2 77  ? 314.366 275.456 283.801 1.00 34.69  ? 75  ARG D CG  1 
ATOM   9551  C  CD  . ARG D 2 77  ? 314.805 276.648 284.633 1.00 36.48  ? 75  ARG D CD  1 
ATOM   9552  N  NE  . ARG D 2 77  ? 313.800 277.027 285.617 1.00 39.46  ? 75  ARG D NE  1 
ATOM   9553  C  CZ  . ARG D 2 77  ? 312.679 277.674 285.331 1.00 46.92  ? 75  ARG D CZ  1 
ATOM   9554  N  NH1 . ARG D 2 77  ? 312.388 278.038 284.093 1.00 40.79  ? 75  ARG D NH1 1 
ATOM   9555  N  NH2 . ARG D 2 77  ? 311.829 277.964 286.312 1.00 49.96  ? 75  ARG D NH2 1 
ATOM   9556  N  N   . VAL D 2 78  ? 312.524 273.507 281.134 1.00 31.91  ? 76  VAL D N   1 
ATOM   9557  C  CA  . VAL D 2 78  ? 311.227 273.565 280.473 1.00 32.35  ? 76  VAL D CA  1 
ATOM   9558  C  C   . VAL D 2 78  ? 310.227 274.157 281.454 1.00 35.98  ? 76  VAL D C   1 
ATOM   9559  O  O   . VAL D 2 78  ? 309.994 273.596 282.532 1.00 37.31  ? 76  VAL D O   1 
ATOM   9560  C  CB  . VAL D 2 78  ? 310.782 272.177 279.988 1.00 32.31  ? 76  VAL D CB  1 
ATOM   9561  C  CG1 . VAL D 2 78  ? 309.427 272.260 279.313 1.00 37.38  ? 76  VAL D CG1 1 
ATOM   9562  C  CG2 . VAL D 2 78  ? 311.816 271.596 279.037 1.00 31.30  ? 76  VAL D CG2 1 
ATOM   9563  N  N   . ASP D 2 79  ? 309.646 275.296 281.082 1.00 40.29  ? 77  ASP D N   1 
ATOM   9564  C  CA  . ASP D 2 79  ? 308.718 276.027 281.936 1.00 45.07  ? 77  ASP D CA  1 
ATOM   9565  C  C   . ASP D 2 79  ? 307.291 275.588 281.633 1.00 46.86  ? 77  ASP D C   1 
ATOM   9566  O  O   . ASP D 2 79  ? 306.811 275.753 280.507 1.00 47.12  ? 77  ASP D O   1 
ATOM   9567  C  CB  . ASP D 2 79  ? 308.872 277.532 281.727 1.00 47.29  ? 77  ASP D CB  1 
ATOM   9568  C  CG  . ASP D 2 79  ? 307.940 278.341 282.606 1.00 60.64  ? 77  ASP D CG  1 
ATOM   9569  O  OD1 . ASP D 2 79  ? 307.695 277.928 283.759 1.00 61.22  ? 77  ASP D OD1 1 
ATOM   9570  O  OD2 . ASP D 2 79  ? 307.444 279.388 282.138 1.00 59.94  ? 77  ASP D OD2 1 
ATOM   9571  N  N   . LEU D 2 80  ? 306.613 275.040 282.642 1.00 46.10  ? 78  LEU D N   1 
ATOM   9572  C  CA  . LEU D 2 80  ? 305.259 274.531 282.461 1.00 46.16  ? 78  LEU D CA  1 
ATOM   9573  C  C   . LEU D 2 80  ? 304.229 275.633 282.253 1.00 49.63  ? 78  LEU D C   1 
ATOM   9574  O  O   . LEU D 2 80  ? 303.095 275.327 281.871 1.00 53.32  ? 78  LEU D O   1 
ATOM   9575  C  CB  . LEU D 2 80  ? 304.859 273.672 283.662 1.00 44.61  ? 78  LEU D CB  1 
ATOM   9576  C  CG  . LEU D 2 80  ? 305.705 272.421 283.910 1.00 39.31  ? 78  LEU D CG  1 
ATOM   9577  C  CD1 . LEU D 2 80  ? 304.887 271.359 284.619 1.00 39.23  ? 78  LEU D CD1 1 
ATOM   9578  C  CD2 . LEU D 2 80  ? 306.270 271.882 282.608 1.00 38.21  ? 78  LEU D CD2 1 
ATOM   9579  N  N   . MET D 2 81  ? 304.584 276.894 282.493 1.00 54.20  ? 79  MET D N   1 
ATOM   9580  C  CA  . MET D 2 81  ? 303.665 278.010 282.315 1.00 54.64  ? 79  MET D CA  1 
ATOM   9581  C  C   . MET D 2 81  ? 303.616 278.512 280.877 1.00 54.06  ? 79  MET D C   1 
ATOM   9582  O  O   . MET D 2 81  ? 303.165 279.638 280.638 1.00 60.28  ? 79  MET D O   1 
ATOM   9583  C  CB  . MET D 2 81  ? 304.035 279.156 283.258 1.00 55.77  ? 79  MET D CB  1 
ATOM   9584  C  CG  . MET D 2 81  ? 303.569 278.952 284.687 1.00 61.32  ? 79  MET D CG  1 
ATOM   9585  S  SD  . MET D 2 81  ? 302.078 277.940 284.779 1.00 81.22  ? 79  MET D SD  1 
ATOM   9586  C  CE  . MET D 2 81  ? 302.496 276.845 286.130 1.00 56.26  ? 79  MET D CE  1 
ATOM   9587  N  N   . GLU D 2 82  ? 304.065 277.708 279.919 1.00 53.00  ? 80  GLU D N   1 
ATOM   9588  C  CA  . GLU D 2 82  ? 304.030 278.063 278.509 1.00 54.56  ? 80  GLU D CA  1 
ATOM   9589  C  C   . GLU D 2 82  ? 303.122 277.102 277.758 1.00 53.48  ? 80  GLU D C   1 
ATOM   9590  O  O   . GLU D 2 82  ? 303.064 275.911 278.078 1.00 52.09  ? 80  GLU D O   1 
ATOM   9591  C  CB  . GLU D 2 82  ? 305.431 278.033 277.894 1.00 50.18  ? 80  GLU D CB  1 
ATOM   9592  C  CG  . GLU D 2 82  ? 306.457 278.865 278.636 1.00 55.18  ? 80  GLU D CG  1 
ATOM   9593  C  CD  . GLU D 2 82  ? 307.698 279.119 277.807 1.00 68.07  ? 80  GLU D CD  1 
ATOM   9594  O  OE1 . GLU D 2 82  ? 307.808 278.533 276.710 1.00 67.84  ? 80  GLU D OE1 1 
ATOM   9595  O  OE2 . GLU D 2 82  ? 308.561 279.906 278.248 1.00 72.62  ? 80  GLU D OE2 1 
ATOM   9596  N  N   . GLU D 2 83  ? 302.409 277.625 276.764 1.00 58.86  ? 81  GLU D N   1 
ATOM   9597  C  CA  . GLU D 2 83  ? 301.629 276.763 275.889 1.00 60.00  ? 81  GLU D CA  1 
ATOM   9598  C  C   . GLU D 2 83  ? 302.557 275.828 275.126 1.00 61.07  ? 81  GLU D C   1 
ATOM   9599  O  O   . GLU D 2 83  ? 303.654 276.214 274.712 1.00 62.77  ? 81  GLU D O   1 
ATOM   9600  C  CB  . GLU D 2 83  ? 300.798 277.597 274.916 1.00 65.10  ? 81  GLU D CB  1 
ATOM   9601  C  CG  . GLU D 2 83  ? 299.457 278.041 275.471 1.00 67.88  ? 81  GLU D CG  1 
ATOM   9602  C  CD  . GLU D 2 83  ? 298.458 276.905 275.546 1.00 67.42  ? 81  GLU D CD  1 
ATOM   9603  O  OE1 . GLU D 2 83  ? 298.292 276.188 274.537 1.00 63.80  ? 81  GLU D OE1 1 
ATOM   9604  O  OE2 . GLU D 2 83  ? 297.836 276.731 276.615 1.00 64.48  ? 81  GLU D OE2 1 
ATOM   9605  N  N   . SER D 2 84  ? 302.110 274.591 274.936 1.00 56.53  ? 82  SER D N   1 
ATOM   9606  C  CA  . SER D 2 84  ? 302.872 273.472 274.400 1.00 58.07  ? 82  SER D CA  1 
ATOM   9607  C  C   . SER D 2 84  ? 303.836 272.913 275.441 1.00 54.11  ? 82  SER D C   1 
ATOM   9608  O  O   . SER D 2 84  ? 304.476 271.893 275.180 1.00 51.83  ? 82  SER D O   1 
ATOM   9609  C  CB  . SER D 2 84  ? 303.660 273.829 273.124 1.00 58.63  ? 82  SER D CB  1 
ATOM   9610  O  OG  . SER D 2 84  ? 304.935 274.360 273.442 1.00 52.88  ? 82  SER D OG  1 
ATOM   9611  N  N   . ASN D 2 85  ? 303.965 273.542 276.611 1.00 47.31  ? 83  ASN D N   1 
ATOM   9612  C  CA  . ASN D 2 85  ? 304.708 272.987 277.731 1.00 40.11  ? 83  ASN D CA  1 
ATOM   9613  C  C   . ASN D 2 85  ? 303.817 272.572 278.890 1.00 42.01  ? 83  ASN D C   1 
ATOM   9614  O  O   . ASN D 2 85  ? 304.255 271.781 279.730 1.00 44.64  ? 83  ASN D O   1 
ATOM   9615  C  CB  . ASN D 2 85  ? 305.741 273.998 278.250 1.00 45.08  ? 83  ASN D CB  1 
ATOM   9616  C  CG  . ASN D 2 85  ? 307.093 273.847 277.590 1.00 41.70  ? 83  ASN D CG  1 
ATOM   9617  O  OD1 . ASN D 2 85  ? 307.319 272.928 276.805 1.00 44.27  ? 83  ASN D OD1 1 
ATOM   9618  N  ND2 . ASN D 2 85  ? 308.006 274.753 277.913 1.00 40.01  ? 83  ASN D ND2 1 
ATOM   9619  N  N   . ALA D 2 86  ? 302.590 273.088 278.956 1.00 41.89  ? 84  ALA D N   1 
ATOM   9620  C  CA  . ALA D 2 86  ? 301.638 272.717 279.992 1.00 37.58  ? 84  ALA D CA  1 
ATOM   9621  C  C   . ALA D 2 86  ? 301.057 271.328 279.780 1.00 39.15  ? 84  ALA D C   1 
ATOM   9622  O  O   . ALA D 2 86  ? 300.178 270.916 280.544 1.00 41.74  ? 84  ALA D O   1 
ATOM   9623  C  CB  . ALA D 2 86  ? 300.509 273.748 280.061 1.00 36.99  ? 84  ALA D CB  1 
ATOM   9624  N  N   . VAL D 2 87  ? 301.525 270.602 278.763 1.00 37.87  ? 85  VAL D N   1 
ATOM   9625  C  CA  . VAL D 2 87  ? 301.099 269.220 278.576 1.00 34.06  ? 85  VAL D CA  1 
ATOM   9626  C  C   . VAL D 2 87  ? 301.478 268.386 279.791 1.00 35.74  ? 85  VAL D C   1 
ATOM   9627  O  O   . VAL D 2 87  ? 300.732 267.491 280.206 1.00 39.36  ? 85  VAL D O   1 
ATOM   9628  C  CB  . VAL D 2 87  ? 301.702 268.650 277.279 1.00 35.57  ? 85  VAL D CB  1 
ATOM   9629  C  CG1 . VAL D 2 87  ? 301.450 267.159 277.183 1.00 35.20  ? 85  VAL D CG1 1 
ATOM   9630  C  CG2 . VAL D 2 87  ? 301.128 269.370 276.072 1.00 33.61  ? 85  VAL D CG2 1 
ATOM   9631  N  N   . LEU D 2 88  ? 302.640 268.665 280.381 1.00 35.54  ? 86  LEU D N   1 
ATOM   9632  C  CA  . LEU D 2 88  ? 303.076 267.975 281.586 1.00 34.78  ? 86  LEU D CA  1 
ATOM   9633  C  C   . LEU D 2 88  ? 302.407 268.503 282.845 1.00 38.00  ? 86  LEU D C   1 
ATOM   9634  O  O   . LEU D 2 88  ? 302.617 267.936 283.922 1.00 38.65  ? 86  LEU D O   1 
ATOM   9635  C  CB  . LEU D 2 88  ? 304.593 268.091 281.743 1.00 34.62  ? 86  LEU D CB  1 
ATOM   9636  C  CG  . LEU D 2 88  ? 305.441 267.953 280.481 1.00 30.79  ? 86  LEU D CG  1 
ATOM   9637  C  CD1 . LEU D 2 88  ? 306.865 268.406 280.751 1.00 26.40  ? 86  LEU D CD1 1 
ATOM   9638  C  CD2 . LEU D 2 88  ? 305.411 266.523 279.980 1.00 30.34  ? 86  LEU D CD2 1 
ATOM   9639  N  N   . TYR D 2 89  ? 301.620 269.569 282.739 1.00 38.35  ? 87  TYR D N   1 
ATOM   9640  C  CA  . TYR D 2 89  ? 301.016 270.225 283.891 1.00 37.78  ? 87  TYR D CA  1 
ATOM   9641  C  C   . TYR D 2 89  ? 299.555 269.852 284.096 1.00 40.90  ? 87  TYR D C   1 
ATOM   9642  O  O   . TYR D 2 89  ? 299.117 269.697 285.239 1.00 44.64  ? 87  TYR D O   1 
ATOM   9643  C  CB  . TYR D 2 89  ? 301.139 271.744 283.742 1.00 39.07  ? 87  TYR D CB  1 
ATOM   9644  C  CG  . TYR D 2 89  ? 300.828 272.521 284.997 1.00 42.60  ? 87  TYR D CG  1 
ATOM   9645  C  CD1 . TYR D 2 89  ? 301.507 272.268 286.181 1.00 40.66  ? 87  TYR D CD1 1 
ATOM   9646  C  CD2 . TYR D 2 89  ? 299.859 273.514 284.996 1.00 43.69  ? 87  TYR D CD2 1 
ATOM   9647  C  CE1 . TYR D 2 89  ? 301.225 272.979 287.329 1.00 45.52  ? 87  TYR D CE1 1 
ATOM   9648  C  CE2 . TYR D 2 89  ? 299.570 274.229 286.138 1.00 45.40  ? 87  TYR D CE2 1 
ATOM   9649  C  CZ  . TYR D 2 89  ? 300.256 273.959 287.302 1.00 49.62  ? 87  TYR D CZ  1 
ATOM   9650  O  OH  . TYR D 2 89  ? 299.970 274.672 288.442 1.00 53.11  ? 87  TYR D OH  1 
ATOM   9651  N  N   . TYR D 2 90  ? 298.797 269.701 283.021 1.00 39.72  ? 88  TYR D N   1 
ATOM   9652  C  CA  . TYR D 2 90  ? 297.367 269.441 283.136 1.00 40.01  ? 88  TYR D CA  1 
ATOM   9653  C  C   . TYR D 2 90  ? 297.119 267.993 283.543 1.00 42.71  ? 88  TYR D C   1 
ATOM   9654  O  O   . TYR D 2 90  ? 297.710 267.082 282.956 1.00 44.82  ? 88  TYR D O   1 
ATOM   9655  C  CB  . TYR D 2 90  ? 296.662 269.734 281.818 1.00 38.57  ? 88  TYR D CB  1 
ATOM   9656  C  CG  . TYR D 2 90  ? 295.157 269.643 281.901 1.00 46.32  ? 88  TYR D CG  1 
ATOM   9657  C  CD1 . TYR D 2 90  ? 294.397 270.741 282.278 1.00 45.71  ? 88  TYR D CD1 1 
ATOM   9658  C  CD2 . TYR D 2 90  ? 294.495 268.461 281.602 1.00 47.17  ? 88  TYR D CD2 1 
ATOM   9659  C  CE1 . TYR D 2 90  ? 293.023 270.663 282.355 1.00 46.85  ? 88  TYR D CE1 1 
ATOM   9660  C  CE2 . TYR D 2 90  ? 293.122 268.374 281.676 1.00 45.57  ? 88  TYR D CE2 1 
ATOM   9661  C  CZ  . TYR D 2 90  ? 292.390 269.477 282.053 1.00 51.06  ? 88  TYR D CZ  1 
ATOM   9662  O  OH  . TYR D 2 90  ? 291.019 269.395 282.128 1.00 56.06  ? 88  TYR D OH  1 
ATOM   9663  N  N   . PRO D 2 91  ? 296.262 267.742 284.539 1.00 47.92  ? 89  PRO D N   1 
ATOM   9664  C  CA  . PRO D 2 91  ? 295.615 268.715 285.431 1.00 44.79  ? 89  PRO D CA  1 
ATOM   9665  C  C   . PRO D 2 91  ? 296.524 269.072 286.599 1.00 45.81  ? 89  PRO D C   1 
ATOM   9666  O  O   . PRO D 2 91  ? 297.266 268.221 287.077 1.00 48.53  ? 89  PRO D O   1 
ATOM   9667  C  CB  . PRO D 2 91  ? 294.339 267.982 285.892 1.00 44.67  ? 89  PRO D CB  1 
ATOM   9668  C  CG  . PRO D 2 91  ? 294.307 266.654 285.156 1.00 45.42  ? 89  PRO D CG  1 
ATOM   9669  C  CD  . PRO D 2 91  ? 295.718 266.392 284.736 1.00 47.63  ? 89  PRO D CD  1 
ATOM   9670  N  N   . PRO D 2 92  ? 296.492 270.314 287.088 1.00 47.53  ? 90  PRO D N   1 
ATOM   9671  C  CA  . PRO D 2 92  ? 297.347 270.661 288.234 1.00 46.70  ? 90  PRO D CA  1 
ATOM   9672  C  C   . PRO D 2 92  ? 297.103 269.778 289.441 1.00 46.76  ? 90  PRO D C   1 
ATOM   9673  O  O   . PRO D 2 92  ? 298.046 269.477 290.184 1.00 48.80  ? 90  PRO D O   1 
ATOM   9674  C  CB  . PRO D 2 92  ? 296.980 272.124 288.514 1.00 46.32  ? 90  PRO D CB  1 
ATOM   9675  C  CG  . PRO D 2 92  ? 296.445 272.632 287.215 1.00 44.55  ? 90  PRO D CG  1 
ATOM   9676  C  CD  . PRO D 2 92  ? 295.735 271.473 286.586 1.00 44.60  ? 90  PRO D CD  1 
ATOM   9677  N  N   . ARG D 2 93  ? 295.865 269.356 289.660 1.00 52.33  ? 91  ARG D N   1 
ATOM   9678  C  CA  . ARG D 2 93  ? 295.518 268.372 290.668 1.00 51.83  ? 91  ARG D CA  1 
ATOM   9679  C  C   . ARG D 2 93  ? 294.649 267.303 290.029 1.00 51.85  ? 91  ARG D C   1 
ATOM   9680  O  O   . ARG D 2 93  ? 293.894 267.588 289.094 1.00 49.23  ? 91  ARG D O   1 
ATOM   9681  C  CB  . ARG D 2 93  ? 294.779 269.009 291.852 1.00 53.60  ? 91  ARG D CB  1 
ATOM   9682  C  CG  . ARG D 2 93  ? 295.593 270.058 292.588 1.00 54.75  ? 91  ARG D CG  1 
ATOM   9683  C  CD  . ARG D 2 93  ? 295.439 269.925 294.092 1.00 64.42  ? 91  ARG D CD  1 
ATOM   9684  N  NE  . ARG D 2 93  ? 296.279 270.867 294.823 1.00 70.14  ? 91  ARG D NE  1 
ATOM   9685  C  CZ  . ARG D 2 93  ? 296.231 272.185 294.684 1.00 69.92  ? 91  ARG D CZ  1 
ATOM   9686  N  NH1 . ARG D 2 93  ? 295.389 272.762 293.843 1.00 65.92  ? 91  ARG D NH1 1 
ATOM   9687  N  NH2 . ARG D 2 93  ? 297.048 272.944 295.409 1.00 66.22  ? 91  ARG D NH2 1 
ATOM   9688  N  N   . PRO D 2 94  ? 294.733 266.065 290.511 1.00 54.85  ? 92  PRO D N   1 
ATOM   9689  C  CA  . PRO D 2 94  ? 294.064 264.962 289.814 1.00 51.92  ? 92  PRO D CA  1 
ATOM   9690  C  C   . PRO D 2 94  ? 292.566 265.196 289.691 1.00 54.19  ? 92  PRO D C   1 
ATOM   9691  O  O   . PRO D 2 94  ? 291.913 265.684 290.615 1.00 55.72  ? 92  PRO D O   1 
ATOM   9692  C  CB  . PRO D 2 94  ? 294.376 263.746 290.694 1.00 49.97  ? 92  PRO D CB  1 
ATOM   9693  C  CG  . PRO D 2 94  ? 295.587 264.139 291.473 1.00 48.02  ? 92  PRO D CG  1 
ATOM   9694  C  CD  . PRO D 2 94  ? 295.458 265.610 291.707 1.00 50.60  ? 92  PRO D CD  1 
ATOM   9695  N  N   . ILE D 2 95  ? 292.028 264.836 288.531 1.00 52.73  ? 93  ILE D N   1 
ATOM   9696  C  CA  . ILE D 2 95  ? 290.600 264.913 288.251 1.00 55.53  ? 93  ILE D CA  1 
ATOM   9697  C  C   . ILE D 2 95  ? 290.151 263.490 287.948 1.00 58.75  ? 93  ILE D C   1 
ATOM   9698  O  O   . ILE D 2 95  ? 290.255 263.025 286.807 1.00 59.20  ? 93  ILE D O   1 
ATOM   9699  C  CB  . ILE D 2 95  ? 290.283 265.862 287.091 1.00 56.37  ? 93  ILE D CB  1 
ATOM   9700  C  CG1 . ILE D 2 95  ? 290.670 267.297 287.451 1.00 54.50  ? 93  ILE D CG1 1 
ATOM   9701  C  CG2 . ILE D 2 95  ? 288.809 265.783 286.724 1.00 55.44  ? 93  ILE D CG2 1 
ATOM   9702  C  CD1 . ILE D 2 95  ? 290.763 268.221 286.257 1.00 50.25  ? 93  ILE D CD1 1 
ATOM   9703  N  N   . GLY D 2 96  ? 289.652 262.793 288.964 1.00 60.80  ? 94  GLY D N   1 
ATOM   9704  C  CA  . GLY D 2 96  ? 289.313 261.393 288.808 1.00 61.53  ? 94  GLY D CA  1 
ATOM   9705  C  C   . GLY D 2 96  ? 290.546 260.542 288.597 1.00 65.80  ? 94  GLY D C   1 
ATOM   9706  O  O   . GLY D 2 96  ? 291.367 260.392 289.506 1.00 67.74  ? 94  GLY D O   1 
ATOM   9707  N  N   . ASP D 2 97  ? 290.692 259.980 287.399 1.00 67.29  ? 95  ASP D N   1 
ATOM   9708  C  CA  . ASP D 2 97  ? 291.865 259.196 287.044 1.00 69.45  ? 95  ASP D CA  1 
ATOM   9709  C  C   . ASP D 2 97  ? 292.849 259.974 286.179 1.00 65.83  ? 95  ASP D C   1 
ATOM   9710  O  O   . ASP D 2 97  ? 293.758 259.374 285.598 1.00 67.06  ? 95  ASP D O   1 
ATOM   9711  C  CB  . ASP D 2 97  ? 291.445 257.908 286.334 1.00 73.70  ? 95  ASP D CB  1 
ATOM   9712  C  CG  . ASP D 2 97  ? 291.964 256.665 287.030 1.00 88.74  ? 95  ASP D CG  1 
ATOM   9713  O  OD1 . ASP D 2 97  ? 293.070 256.724 287.607 1.00 87.63  ? 95  ASP D OD1 1 
ATOM   9714  O  OD2 . ASP D 2 97  ? 291.265 255.631 287.006 1.00 91.56  ? 95  ASP D OD2 1 
ATOM   9715  N  N   . ARG D 2 98  ? 292.690 261.291 286.084 1.00 62.55  ? 96  ARG D N   1 
ATOM   9716  C  CA  . ARG D 2 98  ? 293.562 262.138 285.281 1.00 54.48  ? 96  ARG D CA  1 
ATOM   9717  C  C   . ARG D 2 98  ? 294.602 262.788 286.185 1.00 52.46  ? 96  ARG D C   1 
ATOM   9718  O  O   . ARG D 2 98  ? 294.250 263.501 287.130 1.00 54.73  ? 96  ARG D O   1 
ATOM   9719  C  CB  . ARG D 2 98  ? 292.754 263.205 284.545 1.00 53.95  ? 96  ARG D CB  1 
ATOM   9720  C  CG  . ARG D 2 98  ? 292.791 263.085 283.035 1.00 53.39  ? 96  ARG D CG  1 
ATOM   9721  C  CD  . ARG D 2 98  ? 292.062 264.242 282.377 1.00 52.18  ? 96  ARG D CD  1 
ATOM   9722  N  NE  . ARG D 2 98  ? 292.661 264.603 281.098 1.00 58.04  ? 96  ARG D NE  1 
ATOM   9723  C  CZ  . ARG D 2 98  ? 292.111 265.428 280.218 1.00 61.05  ? 96  ARG D CZ  1 
ATOM   9724  N  NH1 . ARG D 2 98  ? 290.937 265.995 280.442 1.00 56.57  ? 96  ARG D NH1 1 
ATOM   9725  N  NH2 . ARG D 2 98  ? 292.755 265.690 279.084 1.00 55.43  ? 96  ARG D NH2 1 
ATOM   9726  N  N   . LYS D 2 99  ? 295.877 262.544 285.893 1.00 47.36  ? 97  LYS D N   1 
ATOM   9727  C  CA  . LYS D 2 99  ? 296.978 263.126 286.645 1.00 45.70  ? 97  LYS D CA  1 
ATOM   9728  C  C   . LYS D 2 99  ? 297.984 263.742 285.685 1.00 45.06  ? 97  LYS D C   1 
ATOM   9729  O  O   . LYS D 2 99  ? 298.119 263.305 284.539 1.00 46.22  ? 97  LYS D O   1 
ATOM   9730  C  CB  . LYS D 2 99  ? 297.687 262.083 287.519 1.00 41.58  ? 97  LYS D CB  1 
ATOM   9731  C  CG  . LYS D 2 99  ? 296.888 261.613 288.717 1.00 47.04  ? 97  LYS D CG  1 
ATOM   9732  C  CD  . LYS D 2 99  ? 297.470 260.326 289.275 1.00 46.11  ? 97  LYS D CD  1 
ATOM   9733  C  CE  . LYS D 2 99  ? 297.464 259.227 288.226 1.00 49.80  ? 97  LYS D CE  1 
ATOM   9734  N  NZ  . LYS D 2 99  ? 298.681 258.375 288.298 1.00 46.67  ? 97  LYS D NZ  1 
ATOM   9735  N  N   . ASN D 2 100 ? 298.687 264.765 286.162 1.00 42.62  ? 98  ASN D N   1 
ATOM   9736  C  CA  . ASN D 2 100 ? 299.797 265.321 285.407 1.00 37.06  ? 98  ASN D CA  1 
ATOM   9737  C  C   . ASN D 2 100 ? 301.050 264.481 285.649 1.00 38.40  ? 98  ASN D C   1 
ATOM   9738  O  O   . ASN D 2 100 ? 301.029 263.479 286.369 1.00 41.48  ? 98  ASN D O   1 
ATOM   9739  C  CB  . ASN D 2 100 ? 300.005 266.793 285.765 1.00 38.46  ? 98  ASN D CB  1 
ATOM   9740  C  CG  . ASN D 2 100 ? 300.417 267.000 287.209 1.00 38.37  ? 98  ASN D CG  1 
ATOM   9741  O  OD1 . ASN D 2 100 ? 300.585 266.046 287.966 1.00 43.15  ? 98  ASN D OD1 1 
ATOM   9742  N  ND2 . ASN D 2 100 ? 300.577 268.258 287.598 1.00 35.52  ? 98  ASN D ND2 1 
ATOM   9743  N  N   . LEU D 2 101 ? 302.161 264.884 285.029 1.00 37.75  ? 99  LEU D N   1 
ATOM   9744  C  CA  . LEU D 2 101 ? 303.364 264.059 285.072 1.00 36.00  ? 99  LEU D CA  1 
ATOM   9745  C  C   . LEU D 2 101 ? 303.871 263.879 286.499 1.00 35.57  ? 99  LEU D C   1 
ATOM   9746  O  O   . LEU D 2 101 ? 304.222 262.764 286.906 1.00 38.85  ? 99  LEU D O   1 
ATOM   9747  C  CB  . LEU D 2 101 ? 304.449 264.671 284.188 1.00 35.21  ? 99  LEU D CB  1 
ATOM   9748  C  CG  . LEU D 2 101 ? 305.791 263.938 284.149 1.00 34.03  ? 99  LEU D CG  1 
ATOM   9749  C  CD1 . LEU D 2 101 ? 305.610 262.502 283.686 1.00 29.24  ? 99  LEU D CD1 1 
ATOM   9750  C  CD2 . LEU D 2 101 ? 306.771 264.670 283.251 1.00 28.38  ? 99  LEU D CD2 1 
ATOM   9751  N  N   . PHE D 2 102 ? 303.913 264.961 287.279 1.00 34.03  ? 100 PHE D N   1 
ATOM   9752  C  CA  . PHE D 2 102 ? 304.451 264.846 288.630 1.00 36.95  ? 100 PHE D CA  1 
ATOM   9753  C  C   . PHE D 2 102 ? 303.546 264.015 289.527 1.00 41.09  ? 100 PHE D C   1 
ATOM   9754  O  O   . PHE D 2 102 ? 304.038 263.327 290.425 1.00 42.24  ? 100 PHE D O   1 
ATOM   9755  C  CB  . PHE D 2 102 ? 304.681 266.221 289.251 1.00 40.47  ? 100 PHE D CB  1 
ATOM   9756  C  CG  . PHE D 2 102 ? 305.299 266.157 290.618 1.00 42.57  ? 100 PHE D CG  1 
ATOM   9757  C  CD1 . PHE D 2 102 ? 306.616 265.762 290.776 1.00 39.14  ? 100 PHE D CD1 1 
ATOM   9758  C  CD2 . PHE D 2 102 ? 304.560 266.469 291.745 1.00 45.10  ? 100 PHE D CD2 1 
ATOM   9759  C  CE1 . PHE D 2 102 ? 307.186 265.690 292.029 1.00 39.24  ? 100 PHE D CE1 1 
ATOM   9760  C  CE2 . PHE D 2 102 ? 305.126 266.398 293.000 1.00 46.18  ? 100 PHE D CE2 1 
ATOM   9761  C  CZ  . PHE D 2 102 ? 306.440 266.008 293.142 1.00 44.90  ? 100 PHE D CZ  1 
ATOM   9762  N  N   . SER D 2 103 ? 302.230 264.073 289.319 1.00 41.69  ? 101 SER D N   1 
ATOM   9763  C  CA  . SER D 2 103 ? 301.338 263.204 290.079 1.00 40.94  ? 101 SER D CA  1 
ATOM   9764  C  C   . SER D 2 103 ? 301.652 261.738 289.813 1.00 45.79  ? 101 SER D C   1 
ATOM   9765  O  O   . SER D 2 103 ? 301.707 260.926 290.745 1.00 50.21  ? 101 SER D O   1 
ATOM   9766  C  CB  . SER D 2 103 ? 299.882 263.514 289.737 1.00 40.92  ? 101 SER D CB  1 
ATOM   9767  O  OG  . SER D 2 103 ? 299.451 264.701 290.375 1.00 41.84  ? 101 SER D OG  1 
ATOM   9768  N  N   . THR D 2 104 ? 301.874 261.383 288.546 1.00 41.25  ? 102 THR D N   1 
ATOM   9769  C  CA  . THR D 2 104 ? 302.252 260.014 288.212 1.00 41.82  ? 102 THR D CA  1 
ATOM   9770  C  C   . THR D 2 104 ? 303.583 259.635 288.847 1.00 44.01  ? 102 THR D C   1 
ATOM   9771  O  O   . THR D 2 104 ? 303.739 258.524 289.367 1.00 49.61  ? 102 THR D O   1 
ATOM   9772  C  CB  . THR D 2 104 ? 302.320 259.846 286.694 1.00 42.73  ? 102 THR D CB  1 
ATOM   9773  O  OG1 . THR D 2 104 ? 301.066 260.224 286.114 1.00 44.55  ? 102 THR D OG1 1 
ATOM   9774  C  CG2 . THR D 2 104 ? 302.635 258.405 286.329 1.00 42.80  ? 102 THR D CG2 1 
ATOM   9775  N  N   . ILE D 2 105 ? 304.560 260.543 288.806 1.00 39.87  ? 103 ILE D N   1 
ATOM   9776  C  CA  . ILE D 2 105 ? 305.869 260.251 289.388 1.00 40.80  ? 103 ILE D CA  1 
ATOM   9777  C  C   . ILE D 2 105 ? 305.742 260.012 290.888 1.00 46.12  ? 103 ILE D C   1 
ATOM   9778  O  O   . ILE D 2 105 ? 306.309 259.059 291.437 1.00 51.65  ? 103 ILE D O   1 
ATOM   9779  C  CB  . ILE D 2 105 ? 306.857 261.390 289.079 1.00 41.81  ? 103 ILE D CB  1 
ATOM   9780  C  CG1 . ILE D 2 105 ? 307.197 261.411 287.589 1.00 38.71  ? 103 ILE D CG1 1 
ATOM   9781  C  CG2 . ILE D 2 105 ? 308.115 261.246 289.913 1.00 43.36  ? 103 ILE D CG2 1 
ATOM   9782  C  CD1 . ILE D 2 105 ? 307.785 262.717 287.121 1.00 34.49  ? 103 ILE D CD1 1 
ATOM   9783  N  N   . PHE D 2 106 ? 304.999 260.882 291.573 1.00 49.22  ? 104 PHE D N   1 
ATOM   9784  C  CA  . PHE D 2 106 ? 304.806 260.734 293.011 1.00 54.25  ? 104 PHE D CA  1 
ATOM   9785  C  C   . PHE D 2 106 ? 304.076 259.438 293.337 1.00 54.06  ? 104 PHE D C   1 
ATOM   9786  O  O   . PHE D 2 106 ? 304.419 258.751 294.305 1.00 57.93  ? 104 PHE D O   1 
ATOM   9787  C  CB  . PHE D 2 106 ? 304.041 261.939 293.559 1.00 53.60  ? 104 PHE D CB  1 
ATOM   9788  C  CG  . PHE D 2 106 ? 304.146 262.103 295.048 1.00 57.08  ? 104 PHE D CG  1 
ATOM   9789  C  CD1 . PHE D 2 106 ? 303.420 261.292 295.903 1.00 58.45  ? 104 PHE D CD1 1 
ATOM   9790  C  CD2 . PHE D 2 106 ? 304.965 263.076 295.592 1.00 58.88  ? 104 PHE D CD2 1 
ATOM   9791  C  CE1 . PHE D 2 106 ? 303.514 261.446 297.271 1.00 64.05  ? 104 PHE D CE1 1 
ATOM   9792  C  CE2 . PHE D 2 106 ? 305.062 263.234 296.958 1.00 63.16  ? 104 PHE D CE2 1 
ATOM   9793  C  CZ  . PHE D 2 106 ? 304.336 262.418 297.799 1.00 67.72  ? 104 PHE D CZ  1 
ATOM   9794  N  N   . GLY D 2 107 ? 303.062 259.089 292.543 1.00 49.69  ? 105 GLY D N   1 
ATOM   9795  C  CA  . GLY D 2 107 ? 302.362 257.836 292.772 1.00 52.57  ? 105 GLY D CA  1 
ATOM   9796  C  C   . GLY D 2 107 ? 303.261 256.628 292.603 1.00 57.01  ? 105 GLY D C   1 
ATOM   9797  O  O   . GLY D 2 107 ? 303.217 255.691 293.403 1.00 62.57  ? 105 GLY D O   1 
ATOM   9798  N  N   . LEU D 2 108 ? 304.091 256.632 291.557 1.00 53.14  ? 106 LEU D N   1 
ATOM   9799  C  CA  . LEU D 2 108 ? 305.009 255.520 291.340 1.00 47.08  ? 106 LEU D CA  1 
ATOM   9800  C  C   . LEU D 2 108 ? 306.041 255.429 292.457 1.00 51.76  ? 106 LEU D C   1 
ATOM   9801  O  O   . LEU D 2 108 ? 306.438 254.328 292.855 1.00 58.39  ? 106 LEU D O   1 
ATOM   9802  C  CB  . LEU D 2 108 ? 305.693 255.665 289.981 1.00 48.66  ? 106 LEU D CB  1 
ATOM   9803  C  CG  . LEU D 2 108 ? 304.821 255.332 288.770 1.00 47.85  ? 106 LEU D CG  1 
ATOM   9804  C  CD1 . LEU D 2 108 ? 305.388 255.958 287.509 1.00 45.44  ? 106 LEU D CD1 1 
ATOM   9805  C  CD2 . LEU D 2 108 ? 304.685 253.829 288.612 1.00 49.52  ? 106 LEU D CD2 1 
ATOM   9806  N  N   . ILE D 2 109 ? 306.496 256.575 292.969 1.00 54.58  ? 107 ILE D N   1 
ATOM   9807  C  CA  . ILE D 2 109 ? 307.433 256.559 294.088 1.00 56.91  ? 107 ILE D CA  1 
ATOM   9808  C  C   . ILE D 2 109 ? 306.758 256.063 295.360 1.00 62.64  ? 107 ILE D C   1 
ATOM   9809  O  O   . ILE D 2 109 ? 307.405 255.438 296.209 1.00 64.83  ? 107 ILE D O   1 
ATOM   9810  C  CB  . ILE D 2 109 ? 308.056 257.950 294.294 1.00 57.52  ? 107 ILE D CB  1 
ATOM   9811  C  CG1 . ILE D 2 109 ? 308.983 258.297 293.130 1.00 57.73  ? 107 ILE D CG1 1 
ATOM   9812  C  CG2 . ILE D 2 109 ? 308.814 257.997 295.608 1.00 58.97  ? 107 ILE D CG2 1 
ATOM   9813  C  CD1 . ILE D 2 109 ? 309.622 259.658 293.248 1.00 49.82  ? 107 ILE D CD1 1 
ATOM   9814  N  N   . ASN D 2 110 ? 305.467 256.354 295.536 1.00 64.61  ? 108 ASN D N   1 
ATOM   9815  C  CA  . ASN D 2 110 ? 304.757 255.851 296.708 1.00 66.08  ? 108 ASN D CA  1 
ATOM   9816  C  C   . ASN D 2 110 ? 304.797 254.330 296.755 1.00 70.89  ? 108 ASN D C   1 
ATOM   9817  O  O   . ASN D 2 110 ? 304.865 253.734 297.836 1.00 76.17  ? 108 ASN D O   1 
ATOM   9818  C  CB  . ASN D 2 110 ? 303.315 256.354 296.709 1.00 67.72  ? 108 ASN D CB  1 
ATOM   9819  C  CG  . ASN D 2 110 ? 302.844 256.764 298.091 1.00 76.88  ? 108 ASN D CG  1 
ATOM   9820  O  OD1 . ASN D 2 110 ? 303.598 257.347 298.870 1.00 74.42  ? 108 ASN D OD1 1 
ATOM   9821  N  ND2 . ASN D 2 110 ? 301.592 256.455 298.404 1.00 82.39  ? 108 ASN D ND2 1 
ATOM   9822  N  N   . SER D 2 111 ? 304.739 253.687 295.595 1.00 68.48  ? 109 SER D N   1 
ATOM   9823  C  CA  . SER D 2 111 ? 305.025 252.265 295.486 1.00 67.13  ? 109 SER D CA  1 
ATOM   9824  C  C   . SER D 2 111 ? 306.541 252.086 295.432 1.00 69.27  ? 109 SER D C   1 
ATOM   9825  O  O   . SER D 2 111 ? 307.309 253.016 295.687 1.00 71.13  ? 109 SER D O   1 
ATOM   9826  C  CB  . SER D 2 111 ? 304.321 251.676 294.269 1.00 63.39  ? 109 SER D CB  1 
ATOM   9827  O  OG  . SER D 2 111 ? 303.057 252.284 294.074 1.00 65.60  ? 109 SER D OG  1 
ATOM   9828  N  N   . ASN D 2 112 ? 306.996 250.879 295.107 1.00 67.51  ? 110 ASN D N   1 
ATOM   9829  C  CA  . ASN D 2 112 ? 308.413 250.613 294.900 1.00 69.91  ? 110 ASN D CA  1 
ATOM   9830  C  C   . ASN D 2 112 ? 308.737 250.468 293.417 1.00 70.68  ? 110 ASN D C   1 
ATOM   9831  O  O   . ASN D 2 112 ? 309.639 249.717 293.039 1.00 75.44  ? 110 ASN D O   1 
ATOM   9832  C  CB  . ASN D 2 112 ? 308.843 249.365 295.668 1.00 74.57  ? 110 ASN D CB  1 
ATOM   9833  C  CG  . ASN D 2 112 ? 309.478 249.693 297.006 1.00 78.86  ? 110 ASN D CG  1 
ATOM   9834  O  OD1 . ASN D 2 112 ? 308.787 250.030 297.967 1.00 78.33  ? 110 ASN D OD1 1 
ATOM   9835  N  ND2 . ASN D 2 112 ? 310.801 249.593 297.075 1.00 76.26  ? 110 ASN D ND2 1 
ATOM   9836  N  N   . SER D 2 113 ? 308.005 251.187 292.569 1.00 64.40  ? 111 SER D N   1 
ATOM   9837  C  CA  . SER D 2 113 ? 308.060 251.007 291.126 1.00 62.20  ? 111 SER D CA  1 
ATOM   9838  C  C   . SER D 2 113 ? 308.835 252.104 290.403 1.00 60.08  ? 111 SER D C   1 
ATOM   9839  O  O   . SER D 2 113 ? 308.787 252.167 289.172 1.00 63.19  ? 111 SER D O   1 
ATOM   9840  C  CB  . SER D 2 113 ? 306.640 250.916 290.565 1.00 58.90  ? 111 SER D CB  1 
ATOM   9841  O  OG  . SER D 2 113 ? 305.800 251.890 291.158 1.00 60.93  ? 111 SER D OG  1 
ATOM   9842  N  N   . LEU D 2 114 ? 309.548 252.964 291.127 1.00 60.01  ? 112 LEU D N   1 
ATOM   9843  C  CA  . LEU D 2 114 ? 310.330 254.017 290.486 1.00 56.81  ? 112 LEU D CA  1 
ATOM   9844  C  C   . LEU D 2 114 ? 311.506 254.383 291.373 1.00 57.22  ? 112 LEU D C   1 
ATOM   9845  O  O   . LEU D 2 114 ? 311.314 254.781 292.526 1.00 59.68  ? 112 LEU D O   1 
ATOM   9846  C  CB  . LEU D 2 114 ? 309.473 255.251 290.201 1.00 56.15  ? 112 LEU D CB  1 
ATOM   9847  C  CG  . LEU D 2 114 ? 310.063 256.210 289.166 1.00 54.17  ? 112 LEU D CG  1 
ATOM   9848  C  CD1 . LEU D 2 114 ? 309.970 255.606 287.777 1.00 43.84  ? 112 LEU D CD1 1 
ATOM   9849  C  CD2 . LEU D 2 114 ? 309.369 257.563 289.215 1.00 51.15  ? 112 LEU D CD2 1 
ATOM   9850  N  N   . ASP D 2 115 ? 312.715 254.260 290.834 1.00 55.10  ? 113 ASP D N   1 
ATOM   9851  C  CA  . ASP D 2 115 ? 313.932 254.648 291.533 1.00 58.34  ? 113 ASP D CA  1 
ATOM   9852  C  C   . ASP D 2 115 ? 314.361 256.029 291.053 1.00 55.90  ? 113 ASP D C   1 
ATOM   9853  O  O   . ASP D 2 115 ? 314.681 256.209 289.873 1.00 56.08  ? 113 ASP D O   1 
ATOM   9854  C  CB  . ASP D 2 115 ? 315.047 253.629 291.301 1.00 62.72  ? 113 ASP D CB  1 
ATOM   9855  C  CG  . ASP D 2 115 ? 314.967 252.450 292.251 1.00 72.81  ? 113 ASP D CG  1 
ATOM   9856  O  OD1 . ASP D 2 115 ? 314.082 252.451 293.132 1.00 69.88  ? 113 ASP D OD1 1 
ATOM   9857  O  OD2 . ASP D 2 115 ? 315.793 251.523 292.120 1.00 77.73  ? 113 ASP D OD2 1 
ATOM   9858  N  N   . VAL D 2 116 ? 314.369 256.997 291.967 1.00 53.79  ? 114 VAL D N   1 
ATOM   9859  C  CA  . VAL D 2 116 ? 314.792 258.357 291.672 1.00 50.56  ? 114 VAL D CA  1 
ATOM   9860  C  C   . VAL D 2 116 ? 316.016 258.670 292.520 1.00 54.33  ? 114 VAL D C   1 
ATOM   9861  O  O   . VAL D 2 116 ? 316.259 258.050 293.558 1.00 60.08  ? 114 VAL D O   1 
ATOM   9862  C  CB  . VAL D 2 116 ? 313.672 259.389 291.917 1.00 51.65  ? 114 VAL D CB  1 
ATOM   9863  C  CG1 . VAL D 2 116 ? 312.470 259.080 291.038 1.00 46.94  ? 114 VAL D CG1 1 
ATOM   9864  C  CG2 . VAL D 2 116 ? 313.277 259.409 293.383 1.00 50.00  ? 114 VAL D CG2 1 
ATOM   9865  N  N   . TYR D 2 117 ? 316.795 259.647 292.064 1.00 53.29  ? 115 TYR D N   1 
ATOM   9866  C  CA  . TYR D 2 117 ? 318.108 259.911 292.630 1.00 54.37  ? 115 TYR D CA  1 
ATOM   9867  C  C   . TYR D 2 117 ? 318.245 261.382 292.991 1.00 52.02  ? 115 TYR D C   1 
ATOM   9868  O  O   . TYR D 2 117 ? 317.596 262.250 292.401 1.00 50.94  ? 115 TYR D O   1 
ATOM   9869  C  CB  . TYR D 2 117 ? 319.214 259.494 291.656 1.00 52.93  ? 115 TYR D CB  1 
ATOM   9870  C  CG  . TYR D 2 117 ? 319.133 258.036 291.264 1.00 56.40  ? 115 TYR D CG  1 
ATOM   9871  C  CD1 . TYR D 2 117 ? 318.246 257.611 290.285 1.00 55.06  ? 115 TYR D CD1 1 
ATOM   9872  C  CD2 . TYR D 2 117 ? 319.932 257.084 291.879 1.00 61.33  ? 115 TYR D CD2 1 
ATOM   9873  C  CE1 . TYR D 2 117 ? 318.162 256.284 289.925 1.00 57.56  ? 115 TYR D CE1 1 
ATOM   9874  C  CE2 . TYR D 2 117 ? 319.855 255.753 291.524 1.00 63.17  ? 115 TYR D CE2 1 
ATOM   9875  C  CZ  . TYR D 2 117 ? 318.969 255.359 290.546 1.00 63.13  ? 115 TYR D CZ  1 
ATOM   9876  O  OH  . TYR D 2 117 ? 318.886 254.034 290.187 1.00 69.85  ? 115 TYR D OH  1 
ATOM   9877  N  N   . GLU D 2 118 ? 319.107 261.648 293.969 1.00 55.35  ? 116 GLU D N   1 
ATOM   9878  C  CA  . GLU D 2 118 ? 319.251 262.993 294.509 1.00 54.62  ? 116 GLU D CA  1 
ATOM   9879  C  C   . GLU D 2 118 ? 319.768 263.960 293.452 1.00 52.96  ? 116 GLU D C   1 
ATOM   9880  O  O   . GLU D 2 118 ? 320.592 263.604 292.606 1.00 54.01  ? 116 GLU D O   1 
ATOM   9881  C  CB  . GLU D 2 118 ? 320.201 262.977 295.705 1.00 56.66  ? 116 GLU D CB  1 
ATOM   9882  C  CG  . GLU D 2 118 ? 319.583 262.449 296.982 1.00 69.06  ? 116 GLU D CG  1 
ATOM   9883  C  CD  . GLU D 2 118 ? 320.623 262.093 298.023 1.00 79.93  ? 116 GLU D CD  1 
ATOM   9884  O  OE1 . GLU D 2 118 ? 321.792 262.499 297.858 1.00 81.42  ? 116 GLU D OE1 1 
ATOM   9885  O  OE2 . GLU D 2 118 ? 320.272 261.406 299.005 1.00 82.52  ? 116 GLU D OE2 1 
ATOM   9886  N  N   . TYR D 2 119 ? 319.278 265.195 293.512 1.00 52.06  ? 117 TYR D N   1 
ATOM   9887  C  CA  . TYR D 2 119 ? 319.772 266.265 292.654 1.00 51.82  ? 117 TYR D CA  1 
ATOM   9888  C  C   . TYR D 2 119 ? 321.014 266.874 293.291 1.00 55.73  ? 117 TYR D C   1 
ATOM   9889  O  O   . TYR D 2 119 ? 320.923 267.572 294.307 1.00 56.67  ? 117 TYR D O   1 
ATOM   9890  C  CB  . TYR D 2 119 ? 318.695 267.323 292.436 1.00 50.02  ? 117 TYR D CB  1 
ATOM   9891  C  CG  . TYR D 2 119 ? 319.182 268.550 291.696 1.00 49.51  ? 117 TYR D CG  1 
ATOM   9892  C  CD1 . TYR D 2 119 ? 319.731 269.626 292.381 1.00 48.13  ? 117 TYR D CD1 1 
ATOM   9893  C  CD2 . TYR D 2 119 ? 319.098 268.631 290.314 1.00 50.68  ? 117 TYR D CD2 1 
ATOM   9894  C  CE1 . TYR D 2 119 ? 320.178 270.746 291.712 1.00 52.88  ? 117 TYR D CE1 1 
ATOM   9895  C  CE2 . TYR D 2 119 ? 319.542 269.748 289.636 1.00 50.34  ? 117 TYR D CE2 1 
ATOM   9896  C  CZ  . TYR D 2 119 ? 320.082 270.801 290.339 1.00 56.06  ? 117 TYR D CZ  1 
ATOM   9897  O  OH  . TYR D 2 119 ? 320.525 271.915 289.665 1.00 60.32  ? 117 TYR D OH  1 
ATOM   9898  N  N   . LEU D 2 120 ? 322.172 266.614 292.699 1.00 58.76  ? 118 LEU D N   1 
ATOM   9899  C  CA  . LEU D 2 120 ? 323.419 267.233 293.116 1.00 59.62  ? 118 LEU D CA  1 
ATOM   9900  C  C   . LEU D 2 120 ? 323.723 268.436 292.231 1.00 64.07  ? 118 LEU D C   1 
ATOM   9901  O  O   . LEU D 2 120 ? 323.235 268.551 291.105 1.00 63.09  ? 118 LEU D O   1 
ATOM   9902  C  CB  . LEU D 2 120 ? 324.572 266.229 293.060 1.00 60.42  ? 118 LEU D CB  1 
ATOM   9903  C  CG  . LEU D 2 120 ? 324.249 264.815 293.541 1.00 59.98  ? 118 LEU D CG  1 
ATOM   9904  C  CD1 . LEU D 2 120 ? 325.233 263.815 292.961 1.00 63.34  ? 118 LEU D CD1 1 
ATOM   9905  C  CD2 . LEU D 2 120 ? 324.250 264.757 295.060 1.00 59.30  ? 118 LEU D CD2 1 
ATOM   9906  N  N   . ASP D 2 121 ? 324.542 269.340 292.760 1.00 67.95  ? 119 ASP D N   1 
ATOM   9907  C  CA  . ASP D 2 121 ? 324.878 270.589 292.079 1.00 75.95  ? 119 ASP D CA  1 
ATOM   9908  C  C   . ASP D 2 121 ? 326.201 270.398 291.344 1.00 76.43  ? 119 ASP D C   1 
ATOM   9909  O  O   . ASP D 2 121 ? 327.278 270.647 291.886 1.00 76.67  ? 119 ASP D O   1 
ATOM   9910  C  CB  . ASP D 2 121 ? 324.945 271.747 293.070 1.00 78.75  ? 119 ASP D CB  1 
ATOM   9911  C  CG  . ASP D 2 121 ? 325.814 271.438 294.276 1.00 86.36  ? 119 ASP D CG  1 
ATOM   9912  O  OD1 . ASP D 2 121 ? 326.420 270.346 294.319 1.00 85.51  ? 119 ASP D OD1 1 
ATOM   9913  O  OD2 . ASP D 2 121 ? 325.894 272.293 295.183 1.00 88.63  ? 119 ASP D OD2 1 
ATOM   9914  N  N   . GLY D 2 122 ? 326.114 269.956 290.092 1.00 70.73  ? 120 GLY D N   1 
ATOM   9915  C  CA  . GLY D 2 122 ? 327.301 269.821 289.272 1.00 63.94  ? 120 GLY D CA  1 
ATOM   9916  C  C   . GLY D 2 122 ? 327.357 268.567 288.426 1.00 63.17  ? 120 GLY D C   1 
ATOM   9917  O  O   . GLY D 2 122 ? 327.965 268.574 287.352 1.00 66.30  ? 120 GLY D O   1 
ATOM   9918  N  N   . PHE D 2 123 ? 326.730 267.487 288.884 1.00 61.11  ? 121 PHE D N   1 
ATOM   9919  C  CA  . PHE D 2 123 ? 326.820 266.212 288.184 1.00 57.03  ? 121 PHE D CA  1 
ATOM   9920  C  C   . PHE D 2 123 ? 325.614 265.357 288.545 1.00 59.79  ? 121 PHE D C   1 
ATOM   9921  O  O   . PHE D 2 123 ? 324.863 265.664 289.473 1.00 62.68  ? 121 PHE D O   1 
ATOM   9922  C  CB  . PHE D 2 123 ? 328.127 265.485 288.518 1.00 55.66  ? 121 PHE D CB  1 
ATOM   9923  C  CG  . PHE D 2 123 ? 328.246 265.082 289.962 1.00 62.16  ? 121 PHE D CG  1 
ATOM   9924  C  CD1 . PHE D 2 123 ? 328.428 266.034 290.952 1.00 62.11  ? 121 PHE D CD1 1 
ATOM   9925  C  CD2 . PHE D 2 123 ? 328.177 263.750 290.329 1.00 61.61  ? 121 PHE D CD2 1 
ATOM   9926  C  CE1 . PHE D 2 123 ? 328.537 265.664 292.277 1.00 59.97  ? 121 PHE D CE1 1 
ATOM   9927  C  CE2 . PHE D 2 123 ? 328.285 263.374 291.652 1.00 62.59  ? 121 PHE D CE2 1 
ATOM   9928  C  CZ  . PHE D 2 123 ? 328.466 264.332 292.628 1.00 62.26  ? 121 PHE D CZ  1 
ATOM   9929  N  N   . GLU D 2 124 ? 325.442 264.273 287.792 1.00 56.17  ? 122 GLU D N   1 
ATOM   9930  C  CA  . GLU D 2 124 ? 324.355 263.324 287.993 1.00 55.50  ? 122 GLU D CA  1 
ATOM   9931  C  C   . GLU D 2 124 ? 324.940 261.944 288.248 1.00 62.20  ? 122 GLU D C   1 
ATOM   9932  O  O   . GLU D 2 124 ? 325.715 261.434 287.432 1.00 65.38  ? 122 GLU D O   1 
ATOM   9933  C  CB  . GLU D 2 124 ? 323.422 263.281 286.779 1.00 53.89  ? 122 GLU D CB  1 
ATOM   9934  C  CG  . GLU D 2 124 ? 322.568 264.521 286.600 1.00 49.56  ? 122 GLU D CG  1 
ATOM   9935  C  CD  . GLU D 2 124 ? 323.374 265.720 286.152 1.00 54.41  ? 122 GLU D CD  1 
ATOM   9936  O  OE1 . GLU D 2 124 ? 324.169 265.579 285.199 1.00 51.30  ? 122 GLU D OE1 1 
ATOM   9937  O  OE2 . GLU D 2 124 ? 323.219 266.802 286.755 1.00 52.76  ? 122 GLU D OE2 1 
ATOM   9938  N  N   . ALA D 2 125 ? 324.565 261.339 289.373 1.00 65.47  ? 123 ALA D N   1 
ATOM   9939  C  CA  . ALA D 2 125 ? 325.042 260.011 289.754 1.00 64.95  ? 123 ALA D CA  1 
ATOM   9940  C  C   . ALA D 2 125 ? 323.828 259.142 290.068 1.00 63.42  ? 123 ALA D C   1 
ATOM   9941  O  O   . ALA D 2 125 ? 323.245 259.248 291.151 1.00 67.06  ? 123 ALA D O   1 
ATOM   9942  C  CB  . ALA D 2 125 ? 325.992 260.089 290.945 1.00 63.69  ? 123 ALA D CB  1 
ATOM   9943  N  N   . PHE D 2 126 ? 323.449 258.287 289.125 1.00 60.55  ? 124 PHE D N   1 
ATOM   9944  C  CA  . PHE D 2 126 ? 322.308 257.389 289.304 1.00 62.13  ? 124 PHE D CA  1 
ATOM   9945  C  C   . PHE D 2 126 ? 322.776 256.032 289.827 1.00 66.48  ? 124 PHE D C   1 
ATOM   9946  O  O   . PHE D 2 126 ? 322.557 254.984 289.221 1.00 62.28  ? 124 PHE D O   1 
ATOM   9947  C  CB  . PHE D 2 126 ? 321.533 257.247 287.997 1.00 56.05  ? 124 PHE D CB  1 
ATOM   9948  C  CG  . PHE D 2 126 ? 321.170 258.558 287.358 1.00 54.53  ? 124 PHE D CG  1 
ATOM   9949  C  CD1 . PHE D 2 126 ? 320.983 259.693 288.128 1.00 55.95  ? 124 PHE D CD1 1 
ATOM   9950  C  CD2 . PHE D 2 126 ? 321.013 258.653 285.988 1.00 50.63  ? 124 PHE D CD2 1 
ATOM   9951  C  CE1 . PHE D 2 126 ? 320.650 260.896 287.543 1.00 51.91  ? 124 PHE D CE1 1 
ATOM   9952  C  CE2 . PHE D 2 126 ? 320.678 259.854 285.397 1.00 53.64  ? 124 PHE D CE2 1 
ATOM   9953  C  CZ  . PHE D 2 126 ? 320.497 260.977 286.176 1.00 52.90  ? 124 PHE D CZ  1 
ATOM   9954  N  N   . THR D 2 127 ? 323.433 256.072 290.981 1.00 70.43  ? 125 THR D N   1 
ATOM   9955  C  CA  . THR D 2 127 ? 323.953 254.885 291.640 1.00 69.05  ? 125 THR D CA  1 
ATOM   9956  C  C   . THR D 2 127 ? 323.206 254.642 292.944 1.00 72.59  ? 125 THR D C   1 
ATOM   9957  O  O   . THR D 2 127 ? 322.518 255.523 293.467 1.00 75.26  ? 125 THR D O   1 
ATOM   9958  C  CB  . THR D 2 127 ? 325.455 255.019 291.916 1.00 69.00  ? 125 THR D CB  1 
ATOM   9959  O  OG1 . THR D 2 127 ? 325.683 256.126 292.795 1.00 75.77  ? 125 THR D OG1 1 
ATOM   9960  C  CG2 . THR D 2 127 ? 326.217 255.242 290.620 1.00 62.87  ? 125 THR D CG2 1 
ATOM   9961  N  N   . ASP D 2 128 ? 323.351 253.422 293.467 1.00 74.84  ? 126 ASP D N   1 
ATOM   9962  C  CA  . ASP D 2 128 ? 322.636 253.050 294.684 1.00 76.69  ? 126 ASP D CA  1 
ATOM   9963  C  C   . ASP D 2 128 ? 322.976 253.974 295.846 1.00 75.04  ? 126 ASP D C   1 
ATOM   9964  O  O   . ASP D 2 128 ? 322.161 254.146 296.759 1.00 75.56  ? 126 ASP D O   1 
ATOM   9965  C  CB  . ASP D 2 128 ? 322.947 251.600 295.051 1.00 79.45  ? 126 ASP D CB  1 
ATOM   9966  C  CG  . ASP D 2 128 ? 322.160 250.609 294.218 1.00 82.34  ? 126 ASP D CG  1 
ATOM   9967  O  OD1 . ASP D 2 128 ? 321.349 251.051 293.377 1.00 81.76  ? 126 ASP D OD1 1 
ATOM   9968  O  OD2 . ASP D 2 128 ? 322.353 249.390 294.402 1.00 81.90  ? 126 ASP D OD2 1 
ATOM   9969  N  N   . GLN D 2 129 ? 324.167 254.576 295.833 1.00 72.20  ? 127 GLN D N   1 
ATOM   9970  C  CA  . GLN D 2 129 ? 324.538 255.482 296.914 1.00 73.12  ? 127 GLN D CA  1 
ATOM   9971  C  C   . GLN D 2 129 ? 323.691 256.747 296.903 1.00 74.75  ? 127 GLN D C   1 
ATOM   9972  O  O   . GLN D 2 129 ? 323.470 257.352 297.958 1.00 73.84  ? 127 GLN D O   1 
ATOM   9973  C  CB  . GLN D 2 129 ? 326.020 255.840 296.816 1.00 73.65  ? 127 GLN D CB  1 
ATOM   9974  C  CG  . GLN D 2 129 ? 326.356 257.217 297.362 1.00 72.04  ? 127 GLN D CG  1 
ATOM   9975  C  CD  . GLN D 2 129 ? 327.847 257.444 297.490 1.00 79.57  ? 127 GLN D CD  1 
ATOM   9976  O  OE1 . GLN D 2 129 ? 328.630 256.979 296.663 1.00 84.10  ? 127 GLN D OE1 1 
ATOM   9977  N  NE2 . GLN D 2 129 ? 328.248 258.165 298.530 1.00 80.74  ? 127 GLN D NE2 1 
ATOM   9978  N  N   . TYR D 2 130 ? 323.213 257.162 295.732 1.00 75.72  ? 128 TYR D N   1 
ATOM   9979  C  CA  . TYR D 2 130 ? 322.429 258.380 295.594 1.00 68.79  ? 128 TYR D CA  1 
ATOM   9980  C  C   . TYR D 2 130 ? 320.940 258.118 295.427 1.00 67.05  ? 128 TYR D C   1 
ATOM   9981  O  O   . TYR D 2 130 ? 320.175 259.071 295.255 1.00 65.72  ? 128 TYR D O   1 
ATOM   9982  C  CB  . TYR D 2 130 ? 322.948 259.207 294.414 1.00 64.52  ? 128 TYR D CB  1 
ATOM   9983  C  CG  . TYR D 2 130 ? 324.352 259.721 294.623 1.00 69.06  ? 128 TYR D CG  1 
ATOM   9984  C  CD1 . TYR D 2 130 ? 324.578 260.951 295.225 1.00 68.86  ? 128 TYR D CD1 1 
ATOM   9985  C  CD2 . TYR D 2 130 ? 325.452 258.973 294.230 1.00 69.71  ? 128 TYR D CD2 1 
ATOM   9986  C  CE1 . TYR D 2 130 ? 325.859 261.424 295.425 1.00 71.87  ? 128 TYR D CE1 1 
ATOM   9987  C  CE2 . TYR D 2 130 ? 326.737 259.439 294.425 1.00 75.35  ? 128 TYR D CE2 1 
ATOM   9988  C  CZ  . TYR D 2 130 ? 326.935 260.664 295.023 1.00 75.67  ? 128 TYR D CZ  1 
ATOM   9989  O  OH  . TYR D 2 130 ? 328.213 261.132 295.218 1.00 76.27  ? 128 TYR D OH  1 
ATOM   9990  N  N   . LYS D 2 131 ? 320.510 256.859 295.469 1.00 67.64  ? 129 LYS D N   1 
ATOM   9991  C  CA  . LYS D 2 131 ? 319.089 256.557 295.390 1.00 64.54  ? 129 LYS D CA  1 
ATOM   9992  C  C   . LYS D 2 131 ? 318.342 257.267 296.512 1.00 68.57  ? 129 LYS D C   1 
ATOM   9993  O  O   . LYS D 2 131 ? 318.815 257.336 297.649 1.00 76.28  ? 129 LYS D O   1 
ATOM   9994  C  CB  . LYS D 2 131 ? 318.861 255.048 295.466 1.00 66.08  ? 129 LYS D CB  1 
ATOM   9995  C  CG  . LYS D 2 131 ? 317.542 254.590 294.868 1.00 68.32  ? 129 LYS D CG  1 
ATOM   9996  C  CD  . LYS D 2 131 ? 317.482 253.077 294.737 1.00 70.70  ? 129 LYS D CD  1 
ATOM   9997  C  CE  . LYS D 2 131 ? 318.717 252.528 294.044 1.00 74.57  ? 129 LYS D CE  1 
ATOM   9998  N  NZ  . LYS D 2 131 ? 318.542 251.101 293.661 1.00 79.00  ? 129 LYS D NZ  1 
ATOM   9999  N  N   . ILE D 2 132 ? 317.170 257.800 296.186 1.00 65.10  ? 130 ILE D N   1 
ATOM   10000 C  CA  . ILE D 2 132 ? 316.422 258.652 297.102 1.00 69.68  ? 130 ILE D CA  1 
ATOM   10001 C  C   . ILE D 2 132 ? 315.520 257.793 297.975 1.00 74.54  ? 130 ILE D C   1 
ATOM   10002 O  O   . ILE D 2 132 ? 314.758 256.959 297.472 1.00 73.27  ? 130 ILE D O   1 
ATOM   10003 C  CB  . ILE D 2 132 ? 315.601 259.700 296.333 1.00 67.01  ? 130 ILE D CB  1 
ATOM   10004 C  CG1 . ILE D 2 132 ? 316.284 261.067 296.402 1.00 61.93  ? 130 ILE D CG1 1 
ATOM   10005 C  CG2 . ILE D 2 132 ? 314.182 259.772 296.877 1.00 64.05  ? 130 ILE D CG2 1 
ATOM   10006 C  CD1 . ILE D 2 132 ? 315.518 262.162 295.706 1.00 57.14  ? 130 ILE D CD1 1 
ATOM   10007 N  N   . LYS D 2 133 ? 315.607 257.997 299.287 1.00 76.74  ? 131 LYS D N   1 
ATOM   10008 C  CA  . LYS D 2 133 ? 314.697 257.368 300.232 1.00 80.01  ? 131 LYS D CA  1 
ATOM   10009 C  C   . LYS D 2 133 ? 313.453 258.235 300.368 1.00 84.66  ? 131 LYS D C   1 
ATOM   10010 O  O   . LYS D 2 133 ? 313.552 259.429 300.667 1.00 87.51  ? 131 LYS D O   1 
ATOM   10011 C  CB  . LYS D 2 133 ? 315.370 257.179 301.591 1.00 80.39  ? 131 LYS D CB  1 
ATOM   10012 C  CG  . LYS D 2 133 ? 316.198 255.909 301.698 1.00 85.28  ? 131 LYS D CG  1 
ATOM   10013 C  CD  . LYS D 2 133 ? 317.596 256.203 302.216 1.00 87.15  ? 131 LYS D CD  1 
ATOM   10014 C  CE  . LYS D 2 133 ? 318.292 254.934 302.678 1.00 85.16  ? 131 LYS D CE  1 
ATOM   10015 N  NZ  . LYS D 2 133 ? 319.122 254.331 301.601 1.00 86.87  ? 131 LYS D NZ  1 
ATOM   10016 N  N   . PHE D 2 134 ? 312.285 257.633 300.142 1.00 79.65  ? 132 PHE D N   1 
ATOM   10017 C  CA  . PHE D 2 134 ? 311.052 258.412 300.127 1.00 76.10  ? 132 PHE D CA  1 
ATOM   10018 C  C   . PHE D 2 134 ? 310.790 259.060 301.479 1.00 82.41  ? 132 PHE D C   1 
ATOM   10019 O  O   . PHE D 2 134 ? 310.337 260.209 301.546 1.00 80.71  ? 132 PHE D O   1 
ATOM   10020 C  CB  . PHE D 2 134 ? 309.874 257.531 299.715 1.00 72.14  ? 132 PHE D CB  1 
ATOM   10021 C  CG  . PHE D 2 134 ? 308.673 258.307 299.259 1.00 73.73  ? 132 PHE D CG  1 
ATOM   10022 C  CD1 . PHE D 2 134 ? 308.778 259.653 298.956 1.00 74.29  ? 132 PHE D CD1 1 
ATOM   10023 C  CD2 . PHE D 2 134 ? 307.442 257.691 299.128 1.00 74.47  ? 132 PHE D CD2 1 
ATOM   10024 C  CE1 . PHE D 2 134 ? 307.676 260.371 298.534 1.00 70.74  ? 132 PHE D CE1 1 
ATOM   10025 C  CE2 . PHE D 2 134 ? 306.338 258.403 298.706 1.00 71.93  ? 132 PHE D CE2 1 
ATOM   10026 C  CZ  . PHE D 2 134 ? 306.455 259.745 298.409 1.00 66.32  ? 132 PHE D CZ  1 
ATOM   10027 N  N   . GLN D 2 135 ? 311.061 258.339 302.569 1.00 86.67  ? 133 GLN D N   1 
ATOM   10028 C  CA  . GLN D 2 135 ? 310.794 258.885 303.896 1.00 87.80  ? 133 GLN D CA  1 
ATOM   10029 C  C   . GLN D 2 135 ? 311.543 260.193 304.114 1.00 88.18  ? 133 GLN D C   1 
ATOM   10030 O  O   . GLN D 2 135 ? 310.961 261.184 304.568 1.00 87.34  ? 133 GLN D O   1 
ATOM   10031 C  CB  . GLN D 2 135 ? 311.165 257.866 304.973 1.00 93.05  ? 133 GLN D CB  1 
ATOM   10032 C  CG  . GLN D 2 135 ? 311.442 258.486 306.336 1.00 91.30  ? 133 GLN D CG  1 
ATOM   10033 C  CD  . GLN D 2 135 ? 310.192 258.619 307.184 1.00 91.34  ? 133 GLN D CD  1 
ATOM   10034 O  OE1 . GLN D 2 135 ? 309.130 258.110 306.828 1.00 91.40  ? 133 GLN D OE1 1 
ATOM   10035 N  NE2 . GLN D 2 135 ? 310.312 259.311 308.310 1.00 89.34  ? 133 GLN D NE2 1 
ATOM   10036 N  N   . GLU D 2 136 ? 312.833 260.220 303.793 1.00 88.45  ? 134 GLU D N   1 
ATOM   10037 C  CA  . GLU D 2 136 ? 313.617 261.444 303.962 1.00 90.26  ? 134 GLU D CA  1 
ATOM   10038 C  C   . GLU D 2 136 ? 313.614 262.285 302.689 1.00 87.51  ? 134 GLU D C   1 
ATOM   10039 O  O   . GLU D 2 136 ? 314.645 262.750 302.206 1.00 88.56  ? 134 GLU D O   1 
ATOM   10040 C  CB  . GLU D 2 136 ? 315.037 261.094 304.393 1.00 89.41  ? 134 GLU D CB  1 
ATOM   10041 C  CG  . GLU D 2 136 ? 315.949 262.293 304.617 1.00 96.02  ? 134 GLU D CG  1 
ATOM   10042 C  CD  . GLU D 2 136 ? 315.276 263.415 305.387 1.00 97.68  ? 134 GLU D CD  1 
ATOM   10043 O  OE1 . GLU D 2 136 ? 314.324 263.138 306.146 1.00 92.69  ? 134 GLU D OE1 1 
ATOM   10044 O  OE2 . GLU D 2 136 ? 315.704 264.579 305.233 1.00 96.92  ? 134 GLU D OE2 1 
ATOM   10045 N  N   . PHE D 2 137 ? 312.433 262.472 302.137 1.00 83.27  ? 135 PHE D N   1 
ATOM   10046 C  CA  . PHE D 2 137 ? 312.152 263.456 301.099 1.00 81.06  ? 135 PHE D CA  1 
ATOM   10047 C  C   . PHE D 2 137 ? 310.936 264.301 301.437 1.00 81.86  ? 135 PHE D C   1 
ATOM   10048 O  O   . PHE D 2 137 ? 310.954 265.519 301.227 1.00 82.23  ? 135 PHE D O   1 
ATOM   10049 C  CB  . PHE D 2 137 ? 311.956 262.738 299.752 1.00 80.83  ? 135 PHE D CB  1 
ATOM   10050 C  CG  . PHE D 2 137 ? 311.314 263.586 298.693 1.00 75.92  ? 135 PHE D CG  1 
ATOM   10051 C  CD1 . PHE D 2 137 ? 312.077 264.431 297.907 1.00 72.49  ? 135 PHE D CD1 1 
ATOM   10052 C  CD2 . PHE D 2 137 ? 309.949 263.525 298.474 1.00 71.44  ? 135 PHE D CD2 1 
ATOM   10053 C  CE1 . PHE D 2 137 ? 311.487 265.208 296.930 1.00 69.87  ? 135 PHE D CE1 1 
ATOM   10054 C  CE2 . PHE D 2 137 ? 309.355 264.298 297.500 1.00 69.88  ? 135 PHE D CE2 1 
ATOM   10055 C  CZ  . PHE D 2 137 ? 310.125 265.142 296.726 1.00 69.66  ? 135 PHE D CZ  1 
ATOM   10056 N  N   . LEU D 2 138 ? 309.893 263.685 302.000 1.00 82.62  ? 136 LEU D N   1 
ATOM   10057 C  CA  . LEU D 2 138 ? 308.722 264.435 302.436 1.00 80.76  ? 136 LEU D CA  1 
ATOM   10058 C  C   . LEU D 2 138 ? 309.068 265.369 303.586 1.00 84.62  ? 136 LEU D C   1 
ATOM   10059 O  O   . LEU D 2 138 ? 308.633 266.525 303.606 1.00 83.90  ? 136 LEU D O   1 
ATOM   10060 C  CB  . LEU D 2 138 ? 307.608 263.472 302.840 1.00 77.84  ? 136 LEU D CB  1 
ATOM   10061 C  CG  . LEU D 2 138 ? 307.351 262.306 301.885 1.00 73.74  ? 136 LEU D CG  1 
ATOM   10062 C  CD1 . LEU D 2 138 ? 306.769 261.118 302.633 1.00 73.09  ? 136 LEU D CD1 1 
ATOM   10063 C  CD2 . LEU D 2 138 ? 306.431 262.736 300.758 1.00 76.51  ? 136 LEU D CD2 1 
ATOM   10064 N  N   . ASP D 2 139 ? 309.845 264.887 304.557 1.00 87.74  ? 137 ASP D N   1 
ATOM   10065 C  CA  . ASP D 2 139 ? 310.299 265.764 305.631 1.00 88.93  ? 137 ASP D CA  1 
ATOM   10066 C  C   . ASP D 2 139 ? 311.218 266.853 305.094 1.00 87.72  ? 137 ASP D C   1 
ATOM   10067 O  O   . ASP D 2 139 ? 311.140 268.010 305.524 1.00 87.06  ? 137 ASP D O   1 
ATOM   10068 C  CB  . ASP D 2 139 ? 311.000 264.951 306.719 1.00 92.21  ? 137 ASP D CB  1 
ATOM   10069 C  CG  . ASP D 2 139 ? 310.235 263.697 307.094 1.00 93.91  ? 137 ASP D CG  1 
ATOM   10070 O  OD1 . ASP D 2 139 ? 309.257 263.803 307.863 1.00 93.11  ? 137 ASP D OD1 1 
ATOM   10071 O  OD2 . ASP D 2 139 ? 310.615 262.603 306.628 1.00 92.21  ? 137 ASP D OD2 1 
ATOM   10072 N  N   . ARG D 2 140 ? 312.095 266.504 304.150 1.00 88.50  ? 138 ARG D N   1 
ATOM   10073 C  CA  . ARG D 2 140 ? 313.022 267.493 303.611 1.00 87.26  ? 138 ARG D CA  1 
ATOM   10074 C  C   . ARG D 2 140 ? 312.279 268.631 302.921 1.00 85.73  ? 138 ARG D C   1 
ATOM   10075 O  O   . ARG D 2 140 ? 312.625 269.804 303.100 1.00 87.27  ? 138 ARG D O   1 
ATOM   10076 C  CB  . ARG D 2 140 ? 314.002 266.827 302.647 1.00 84.86  ? 138 ARG D CB  1 
ATOM   10077 C  CG  . ARG D 2 140 ? 315.124 267.742 302.185 1.00 84.66  ? 138 ARG D CG  1 
ATOM   10078 C  CD  . ARG D 2 140 ? 315.478 267.496 300.730 1.00 87.03  ? 138 ARG D CD  1 
ATOM   10079 N  NE  . ARG D 2 140 ? 316.916 267.378 300.527 1.00 98.88  ? 138 ARG D NE  1 
ATOM   10080 C  CZ  . ARG D 2 140 ? 317.677 268.325 299.996 1.00 100.52 ? 138 ARG D CZ  1 
ATOM   10081 N  NH1 . ARG D 2 140 ? 317.168 269.482 299.605 1.00 95.51  ? 138 ARG D NH1 1 
ATOM   10082 N  NH2 . ARG D 2 140 ? 318.981 268.106 299.853 1.00 96.84  ? 138 ARG D NH2 1 
ATOM   10083 N  N   . PHE D 2 141 ? 311.255 268.309 302.130 1.00 84.66  ? 139 PHE D N   1 
ATOM   10084 C  CA  . PHE D 2 141 ? 310.468 269.329 301.447 1.00 83.97  ? 139 PHE D CA  1 
ATOM   10085 C  C   . PHE D 2 141 ? 309.140 269.620 302.136 1.00 85.46  ? 139 PHE D C   1 
ATOM   10086 O  O   . PHE D 2 141 ? 308.293 270.309 301.557 1.00 84.47  ? 139 PHE D O   1 
ATOM   10087 C  CB  . PHE D 2 141 ? 310.235 268.935 299.988 1.00 80.23  ? 139 PHE D CB  1 
ATOM   10088 C  CG  . PHE D 2 141 ? 311.499 268.804 299.188 1.00 80.16  ? 139 PHE D CG  1 
ATOM   10089 C  CD1 . PHE D 2 141 ? 312.001 269.888 298.488 1.00 78.08  ? 139 PHE D CD1 1 
ATOM   10090 C  CD2 . PHE D 2 141 ? 312.185 267.605 299.135 1.00 80.90  ? 139 PHE D CD2 1 
ATOM   10091 C  CE1 . PHE D 2 141 ? 313.163 269.779 297.753 1.00 77.71  ? 139 PHE D CE1 1 
ATOM   10092 C  CE2 . PHE D 2 141 ? 313.348 267.490 298.397 1.00 77.93  ? 139 PHE D CE2 1 
ATOM   10093 C  CZ  . PHE D 2 141 ? 313.837 268.579 297.707 1.00 75.22  ? 139 PHE D CZ  1 
ATOM   10094 N  N   . GLY D 2 142 ? 308.940 269.123 303.353 1.00 84.12  ? 140 GLY D N   1 
ATOM   10095 C  CA  . GLY D 2 142 ? 307.768 269.471 304.132 1.00 83.31  ? 140 GLY D CA  1 
ATOM   10096 C  C   . GLY D 2 142 ? 306.442 269.029 303.546 1.00 82.30  ? 140 GLY D C   1 
ATOM   10097 O  O   . GLY D 2 142 ? 305.492 269.815 303.492 1.00 78.70  ? 140 GLY D O   1 
ATOM   10098 N  N   . ILE D 2 143 ? 306.361 267.779 303.102 1.00 82.11  ? 141 ILE D N   1 
ATOM   10099 C  CA  . ILE D 2 143 ? 305.125 267.207 302.582 1.00 81.96  ? 141 ILE D CA  1 
ATOM   10100 C  C   . ILE D 2 143 ? 304.473 266.400 303.696 1.00 84.63  ? 141 ILE D C   1 
ATOM   10101 O  O   . ILE D 2 143 ? 305.084 265.475 304.246 1.00 81.99  ? 141 ILE D O   1 
ATOM   10102 C  CB  . ILE D 2 143 ? 305.382 266.335 301.344 1.00 78.39  ? 141 ILE D CB  1 
ATOM   10103 C  CG1 . ILE D 2 143 ? 305.835 267.199 300.167 1.00 75.85  ? 141 ILE D CG1 1 
ATOM   10104 C  CG2 . ILE D 2 143 ? 304.130 265.561 300.974 1.00 76.58  ? 141 ILE D CG2 1 
ATOM   10105 C  CD1 . ILE D 2 143 ? 306.997 266.618 299.397 1.00 75.77  ? 141 ILE D CD1 1 
ATOM   10106 N  N   . TYR D 2 144 ? 303.234 266.749 304.031 1.00 88.04  ? 142 TYR D N   1 
ATOM   10107 C  CA  . TYR D 2 144 ? 302.525 266.066 305.102 1.00 87.97  ? 142 TYR D CA  1 
ATOM   10108 C  C   . TYR D 2 144 ? 302.199 264.633 304.699 1.00 88.60  ? 142 TYR D C   1 
ATOM   10109 O  O   . TYR D 2 144 ? 301.803 264.365 303.562 1.00 89.85  ? 142 TYR D O   1 
ATOM   10110 C  CB  . TYR D 2 144 ? 301.244 266.824 305.448 1.00 90.00  ? 142 TYR D CB  1 
ATOM   10111 C  CG  . TYR D 2 144 ? 300.577 266.371 306.725 1.00 94.30  ? 142 TYR D CG  1 
ATOM   10112 C  CD1 . TYR D 2 144 ? 301.325 265.875 307.784 1.00 93.62  ? 142 TYR D CD1 1 
ATOM   10113 C  CD2 . TYR D 2 144 ? 299.200 266.447 306.875 1.00 93.59  ? 142 TYR D CD2 1 
ATOM   10114 C  CE1 . TYR D 2 144 ? 300.718 265.463 308.954 1.00 96.34  ? 142 TYR D CE1 1 
ATOM   10115 C  CE2 . TYR D 2 144 ? 298.585 266.038 308.040 1.00 96.87  ? 142 TYR D CE2 1 
ATOM   10116 C  CZ  . TYR D 2 144 ? 299.348 265.546 309.077 1.00 100.37 ? 142 TYR D CZ  1 
ATOM   10117 O  OH  . TYR D 2 144 ? 298.738 265.137 310.240 1.00 101.29 ? 142 TYR D OH  1 
ATOM   10118 N  N   . TYR D 2 145 ? 302.367 263.707 305.642 1.00 87.73  ? 143 TYR D N   1 
ATOM   10119 C  CA  . TYR D 2 145 ? 302.112 262.300 305.375 1.00 87.83  ? 143 TYR D CA  1 
ATOM   10120 C  C   . TYR D 2 145 ? 301.736 261.594 306.670 1.00 90.85  ? 143 TYR D C   1 
ATOM   10121 O  O   . TYR D 2 145 ? 302.001 262.084 307.771 1.00 91.82  ? 143 TYR D O   1 
ATOM   10122 C  CB  . TYR D 2 145 ? 303.324 261.619 304.726 1.00 86.77  ? 143 TYR D CB  1 
ATOM   10123 C  CG  . TYR D 2 145 ? 304.492 261.407 305.662 1.00 80.55  ? 143 TYR D CG  1 
ATOM   10124 C  CD1 . TYR D 2 145 ? 305.404 262.424 305.905 1.00 80.89  ? 143 TYR D CD1 1 
ATOM   10125 C  CD2 . TYR D 2 145 ? 304.687 260.189 306.294 1.00 81.74  ? 143 TYR D CD2 1 
ATOM   10126 C  CE1 . TYR D 2 145 ? 306.474 262.234 306.755 1.00 81.89  ? 143 TYR D CE1 1 
ATOM   10127 C  CE2 . TYR D 2 145 ? 305.753 259.989 307.146 1.00 81.88  ? 143 TYR D CE2 1 
ATOM   10128 C  CZ  . TYR D 2 145 ? 306.644 261.014 307.373 1.00 84.75  ? 143 TYR D CZ  1 
ATOM   10129 O  OH  . TYR D 2 145 ? 307.708 260.817 308.222 1.00 85.66  ? 143 TYR D OH  1 
ATOM   10130 N  N   . GLN D 2 146 ? 301.115 260.434 306.519 1.00 93.05  ? 144 GLN D N   1 
ATOM   10131 C  CA  . GLN D 2 146 ? 300.644 259.608 307.617 1.00 95.25  ? 144 GLN D CA  1 
ATOM   10132 C  C   . GLN D 2 146 ? 301.065 258.168 307.384 1.00 96.10  ? 144 GLN D C   1 
ATOM   10133 O  O   . GLN D 2 146 ? 301.407 257.786 306.260 1.00 93.02  ? 144 GLN D O   1 
ATOM   10134 C  CB  . GLN D 2 146 ? 299.116 259.678 307.754 1.00 95.08  ? 144 GLN D CB  1 
ATOM   10135 C  CG  . GLN D 2 146 ? 298.616 260.859 308.564 1.00 95.20  ? 144 GLN D CG  1 
ATOM   10136 C  CD  . GLN D 2 146 ? 297.456 261.566 307.896 1.00 95.81  ? 144 GLN D CD  1 
ATOM   10137 O  OE1 . GLN D 2 146 ? 296.506 260.931 307.441 1.00 93.50  ? 144 GLN D OE1 1 
ATOM   10138 N  NE2 . GLN D 2 146 ? 297.530 262.890 307.830 1.00 93.90  ? 144 GLN D NE2 1 
ATOM   10139 N  N   . PRO D 2 147 ? 301.065 257.344 308.429 1.00 100.85 ? 145 PRO D N   1 
ATOM   10140 C  CA  . PRO D 2 147 ? 301.329 255.916 308.232 1.00 101.41 ? 145 PRO D CA  1 
ATOM   10141 C  C   . PRO D 2 147 ? 300.330 255.315 307.254 1.00 98.94  ? 145 PRO D C   1 
ATOM   10142 O  O   . PRO D 2 147 ? 299.149 255.667 307.248 1.00 97.17  ? 145 PRO D O   1 
ATOM   10143 C  CB  . PRO D 2 147 ? 301.172 255.328 309.638 1.00 100.05 ? 145 PRO D CB  1 
ATOM   10144 C  CG  . PRO D 2 147 ? 301.436 256.476 310.556 1.00 98.08  ? 145 PRO D CG  1 
ATOM   10145 C  CD  . PRO D 2 147 ? 300.914 257.693 309.852 1.00 98.28  ? 145 PRO D CD  1 
ATOM   10146 N  N   . SER D 2 148 ? 300.819 254.407 306.417 1.00 97.41  ? 146 SER D N   1 
ATOM   10147 C  CA  . SER D 2 148 ? 299.992 253.828 305.372 1.00 98.27  ? 146 SER D CA  1 
ATOM   10148 C  C   . SER D 2 148 ? 299.054 252.769 305.943 1.00 105.51 ? 146 SER D C   1 
ATOM   10149 O  O   . SER D 2 148 ? 299.255 252.247 307.043 1.00 107.45 ? 146 SER D O   1 
ATOM   10150 C  CB  . SER D 2 148 ? 300.863 253.216 304.275 1.00 94.55  ? 146 SER D CB  1 
ATOM   10151 O  OG  . SER D 2 148 ? 301.729 252.229 304.805 1.00 91.92  ? 146 SER D OG  1 
ATOM   10152 N  N   . THR D 2 149 ? 298.010 252.461 305.175 1.00 106.88 ? 147 THR D N   1 
ATOM   10153 C  CA  . THR D 2 149 ? 297.097 251.384 305.533 1.00 108.91 ? 147 THR D CA  1 
ATOM   10154 C  C   . THR D 2 149 ? 297.538 250.035 304.985 1.00 110.02 ? 147 THR D C   1 
ATOM   10155 O  O   . THR D 2 149 ? 296.970 249.010 305.375 1.00 108.92 ? 147 THR D O   1 
ATOM   10156 C  CB  . THR D 2 149 ? 295.683 251.699 305.034 1.00 111.26 ? 147 THR D CB  1 
ATOM   10157 O  OG1 . THR D 2 149 ? 295.556 251.299 303.663 1.00 103.39 ? 147 THR D OG1 1 
ATOM   10158 C  CG2 . THR D 2 149 ? 295.401 253.191 305.146 1.00 105.84 ? 147 THR D CG2 1 
ATOM   10159 N  N   . ASN D 2 150 ? 298.536 250.011 304.102 1.00 110.66 ? 148 ASN D N   1 
ATOM   10160 C  CA  . ASN D 2 150 ? 299.017 248.769 303.512 1.00 108.72 ? 148 ASN D CA  1 
ATOM   10161 C  C   . ASN D 2 150 ? 300.367 249.034 302.865 1.00 104.69 ? 148 ASN D C   1 
ATOM   10162 O  O   . ASN D 2 150 ? 300.506 249.981 302.085 1.00 103.36 ? 148 ASN D O   1 
ATOM   10163 C  CB  . ASN D 2 150 ? 298.019 248.225 302.485 1.00 107.59 ? 148 ASN D CB  1 
ATOM   10164 C  CG  . ASN D 2 150 ? 298.216 246.748 302.209 1.00 111.35 ? 148 ASN D CG  1 
ATOM   10165 O  OD1 . ASN D 2 150 ? 299.191 246.145 302.656 1.00 111.44 ? 148 ASN D OD1 1 
ATOM   10166 N  ND2 . ASN D 2 150 ? 297.285 246.155 301.470 1.00 110.65 ? 148 ASN D ND2 1 
ATOM   10167 N  N   . LYS D 2 151 ? 301.355 248.198 303.188 1.00 106.38 ? 149 LYS D N   1 
ATOM   10168 C  CA  . LYS D 2 151 ? 302.714 248.405 302.703 1.00 107.25 ? 149 LYS D CA  1 
ATOM   10169 C  C   . LYS D 2 151 ? 302.868 248.130 301.213 1.00 109.04 ? 149 LYS D C   1 
ATOM   10170 O  O   . LYS D 2 151 ? 303.908 248.480 300.645 1.00 104.36 ? 149 LYS D O   1 
ATOM   10171 C  CB  . LYS D 2 151 ? 303.693 247.530 303.490 1.00 105.92 ? 149 LYS D CB  1 
ATOM   10172 C  CG  . LYS D 2 151 ? 303.957 247.998 304.917 1.00 102.68 ? 149 LYS D CG  1 
ATOM   10173 C  CD  . LYS D 2 151 ? 302.725 247.854 305.796 1.00 106.17 ? 149 LYS D CD  1 
ATOM   10174 C  CE  . LYS D 2 151 ? 302.075 246.492 305.619 1.00 107.45 ? 149 LYS D CE  1 
ATOM   10175 N  NZ  . LYS D 2 151 ? 300.617 246.527 305.918 1.00 101.58 ? 149 LYS D NZ  1 
ATOM   10176 N  N   . ASN D 2 152 ? 301.877 247.521 300.569 1.00 108.46 ? 150 ASN D N   1 
ATOM   10177 C  CA  . ASN D 2 152 ? 301.950 247.230 299.143 1.00 106.02 ? 150 ASN D CA  1 
ATOM   10178 C  C   . ASN D 2 152 ? 301.451 248.436 298.355 1.00 103.87 ? 150 ASN D C   1 
ATOM   10179 O  O   . ASN D 2 152 ? 300.350 248.939 298.607 1.00 100.80 ? 150 ASN D O   1 
ATOM   10180 C  CB  . ASN D 2 152 ? 301.145 245.977 298.798 1.00 105.94 ? 150 ASN D CB  1 
ATOM   10181 C  CG  . ASN D 2 152 ? 299.763 245.975 299.424 1.00 108.97 ? 150 ASN D CG  1 
ATOM   10182 O  OD1 . ASN D 2 152 ? 299.104 247.010 299.512 1.00 110.87 ? 150 ASN D OD1 1 
ATOM   10183 N  ND2 . ASN D 2 152 ? 299.317 244.804 299.863 1.00 106.93 ? 150 ASN D ND2 1 
ATOM   10184 N  N   . ALA D 2 153 ? 302.267 248.905 297.413 1.00 98.93  ? 151 ALA D N   1 
ATOM   10185 C  CA  . ALA D 2 153 ? 301.946 250.061 296.581 1.00 98.03  ? 151 ALA D CA  1 
ATOM   10186 C  C   . ALA D 2 153 ? 301.617 251.300 297.408 1.00 95.86  ? 151 ALA D C   1 
ATOM   10187 O  O   . ALA D 2 153 ? 300.999 252.241 296.902 1.00 92.51  ? 151 ALA D O   1 
ATOM   10188 C  CB  . ALA D 2 153 ? 300.792 249.750 295.621 1.00 93.82  ? 151 ALA D CB  1 
ATOM   10189 N  N   . GLU D 2 154 ? 302.022 251.318 298.681 1.00 92.49  ? 152 GLU D N   1 
ATOM   10190 C  CA  . GLU D 2 154 ? 301.767 252.470 299.543 1.00 91.72  ? 152 GLU D CA  1 
ATOM   10191 C  C   . GLU D 2 154 ? 302.825 252.472 300.646 1.00 90.85  ? 152 GLU D C   1 
ATOM   10192 O  O   . GLU D 2 154 ? 302.710 251.715 301.613 1.00 97.51  ? 152 GLU D O   1 
ATOM   10193 C  CB  . GLU D 2 154 ? 300.363 252.423 300.123 1.00 93.97  ? 152 GLU D CB  1 
ATOM   10194 C  CG  . GLU D 2 154 ? 299.832 253.776 300.560 1.00 92.84  ? 152 GLU D CG  1 
ATOM   10195 C  CD  . GLU D 2 154 ? 299.032 254.467 299.479 1.00 96.89  ? 152 GLU D CD  1 
ATOM   10196 O  OE1 . GLU D 2 154 ? 298.912 253.902 298.373 1.00 99.21  ? 152 GLU D OE1 1 
ATOM   10197 O  OE2 . GLU D 2 154 ? 298.521 255.577 299.738 1.00 96.95  ? 152 GLU D OE2 1 
ATOM   10198 N  N   . LEU D 2 155 ? 303.842 253.319 300.488 1.00 83.81  ? 153 LEU D N   1 
ATOM   10199 C  CA  . LEU D 2 155 ? 304.824 253.492 301.551 1.00 81.47  ? 153 LEU D CA  1 
ATOM   10200 C  C   . LEU D 2 155 ? 304.269 254.348 302.681 1.00 83.23  ? 153 LEU D C   1 
ATOM   10201 O  O   . LEU D 2 155 ? 304.548 254.089 303.857 1.00 85.81  ? 153 LEU D O   1 
ATOM   10202 C  CB  . LEU D 2 155 ? 306.103 254.118 300.995 1.00 82.98  ? 153 LEU D CB  1 
ATOM   10203 C  CG  . LEU D 2 155 ? 306.888 253.311 299.961 1.00 79.18  ? 153 LEU D CG  1 
ATOM   10204 C  CD1 . LEU D 2 155 ? 308.139 254.067 299.542 1.00 75.44  ? 153 LEU D CD1 1 
ATOM   10205 C  CD2 . LEU D 2 155 ? 307.244 251.941 300.510 1.00 74.84  ? 153 LEU D CD2 1 
ATOM   10206 N  N   . PHE D 2 156 ? 303.487 255.370 302.343 1.00 83.66  ? 154 PHE D N   1 
ATOM   10207 C  CA  . PHE D 2 156 ? 302.910 256.270 303.327 1.00 83.27  ? 154 PHE D CA  1 
ATOM   10208 C  C   . PHE D 2 156 ? 301.533 256.697 302.837 1.00 86.09  ? 154 PHE D C   1 
ATOM   10209 O  O   . PHE D 2 156 ? 301.050 256.236 301.799 1.00 87.86  ? 154 PHE D O   1 
ATOM   10210 C  CB  . PHE D 2 156 ? 303.820 257.478 303.572 1.00 80.96  ? 154 PHE D CB  1 
ATOM   10211 C  CG  . PHE D 2 156 ? 305.220 257.109 303.974 1.00 82.61  ? 154 PHE D CG  1 
ATOM   10212 C  CD1 . PHE D 2 156 ? 306.185 256.847 303.015 1.00 83.19  ? 154 PHE D CD1 1 
ATOM   10213 C  CD2 . PHE D 2 156 ? 305.566 257.011 305.310 1.00 80.54  ? 154 PHE D CD2 1 
ATOM   10214 C  CE1 . PHE D 2 156 ? 307.471 256.503 303.382 1.00 81.51  ? 154 PHE D CE1 1 
ATOM   10215 C  CE2 . PHE D 2 156 ? 306.849 256.666 305.682 1.00 80.55  ? 154 PHE D CE2 1 
ATOM   10216 C  CZ  . PHE D 2 156 ? 307.802 256.412 304.718 1.00 80.34  ? 154 PHE D CZ  1 
ATOM   10217 N  N   . LYS D 2 157 ? 300.896 257.583 303.598 1.00 90.45  ? 155 LYS D N   1 
ATOM   10218 C  CA  . LYS D 2 157 ? 299.593 258.140 303.247 1.00 92.63  ? 155 LYS D CA  1 
ATOM   10219 C  C   . LYS D 2 157 ? 299.763 259.638 303.035 1.00 89.44  ? 155 LYS D C   1 
ATOM   10220 O  O   . LYS D 2 157 ? 300.079 260.371 303.977 1.00 89.92  ? 155 LYS D O   1 
ATOM   10221 C  CB  . LYS D 2 157 ? 298.558 257.851 304.334 1.00 94.95  ? 155 LYS D CB  1 
ATOM   10222 C  CG  . LYS D 2 157 ? 297.277 258.658 304.197 1.00 94.50  ? 155 LYS D CG  1 
ATOM   10223 C  CD  . LYS D 2 157 ? 296.296 258.335 305.311 1.00 98.10  ? 155 LYS D CD  1 
ATOM   10224 C  CE  . LYS D 2 157 ? 295.121 257.524 304.791 1.00 99.27  ? 155 LYS D CE  1 
ATOM   10225 N  NZ  . LYS D 2 157 ? 294.385 258.246 303.717 1.00 93.39  ? 155 LYS D NZ  1 
ATOM   10226 N  N   . VAL D 2 158 ? 299.555 260.091 301.801 1.00 88.64  ? 156 VAL D N   1 
ATOM   10227 C  CA  . VAL D 2 158 ? 299.712 261.494 301.439 1.00 87.90  ? 156 VAL D CA  1 
ATOM   10228 C  C   . VAL D 2 158 ? 298.436 261.963 300.757 1.00 84.75  ? 156 VAL D C   1 
ATOM   10229 O  O   . VAL D 2 158 ? 297.959 261.322 299.813 1.00 79.29  ? 156 VAL D O   1 
ATOM   10230 C  CB  . VAL D 2 158 ? 300.928 261.715 300.519 1.00 81.03  ? 156 VAL D CB  1 
ATOM   10231 C  CG1 . VAL D 2 158 ? 301.389 263.161 300.590 1.00 78.18  ? 156 VAL D CG1 1 
ATOM   10232 C  CG2 . VAL D 2 158 ? 302.057 260.768 300.895 1.00 78.59  ? 156 VAL D CG2 1 
ATOM   10233 N  N   . ALA D 2 159 ? 297.885 263.075 301.234 1.00 83.38  ? 157 ALA D N   1 
ATOM   10234 C  CA  . ALA D 2 159 ? 296.708 263.660 300.617 1.00 83.44  ? 157 ALA D CA  1 
ATOM   10235 C  C   . ALA D 2 159 ? 297.088 264.392 299.333 1.00 81.46  ? 157 ALA D C   1 
ATOM   10236 O  O   . ALA D 2 159 ? 298.232 264.810 299.138 1.00 83.63  ? 157 ALA D O   1 
ATOM   10237 C  CB  . ALA D 2 159 ? 296.012 264.618 301.584 1.00 84.22  ? 157 ALA D CB  1 
ATOM   10238 N  N   . ASP D 2 160 ? 296.101 264.547 298.448 1.00 76.63  ? 158 ASP D N   1 
ATOM   10239 C  CA  . ASP D 2 160 ? 296.352 265.226 297.181 1.00 80.18  ? 158 ASP D CA  1 
ATOM   10240 C  C   . ASP D 2 160 ? 296.787 266.668 297.404 1.00 80.36  ? 158 ASP D C   1 
ATOM   10241 O  O   . ASP D 2 160 ? 297.689 267.164 296.720 1.00 77.88  ? 158 ASP D O   1 
ATOM   10242 C  CB  . ASP D 2 160 ? 295.107 265.169 296.297 1.00 78.57  ? 158 ASP D CB  1 
ATOM   10243 C  CG  . ASP D 2 160 ? 295.111 263.975 295.365 1.00 79.28  ? 158 ASP D CG  1 
ATOM   10244 O  OD1 . ASP D 2 160 ? 296.167 263.320 295.242 1.00 80.27  ? 158 ASP D OD1 1 
ATOM   10245 O  OD2 . ASP D 2 160 ? 294.058 263.689 294.758 1.00 77.39  ? 158 ASP D OD2 1 
ATOM   10246 N  N   . SER D 2 161 ? 296.157 267.360 298.354 1.00 80.79  ? 159 SER D N   1 
ATOM   10247 C  CA  . SER D 2 161 ? 296.552 268.731 298.649 1.00 82.62  ? 159 SER D CA  1 
ATOM   10248 C  C   . SER D 2 161 ? 297.998 268.822 299.121 1.00 83.27  ? 159 SER D C   1 
ATOM   10249 O  O   . SER D 2 161 ? 298.619 269.880 298.978 1.00 77.83  ? 159 SER D O   1 
ATOM   10250 C  CB  . SER D 2 161 ? 295.616 269.332 299.699 1.00 80.87  ? 159 SER D CB  1 
ATOM   10251 O  OG  . SER D 2 161 ? 295.466 268.459 300.804 1.00 86.62  ? 159 SER D OG  1 
ATOM   10252 N  N   . ASP D 2 162 ? 298.546 267.739 299.676 1.00 83.08  ? 160 ASP D N   1 
ATOM   10253 C  CA  . ASP D 2 162 ? 299.939 267.742 300.107 1.00 80.36  ? 160 ASP D CA  1 
ATOM   10254 C  C   . ASP D 2 162 ? 300.895 267.610 298.927 1.00 75.13  ? 160 ASP D C   1 
ATOM   10255 O  O   . ASP D 2 162 ? 301.968 268.223 298.923 1.00 74.24  ? 160 ASP D O   1 
ATOM   10256 C  CB  . ASP D 2 162 ? 300.181 266.612 301.107 1.00 82.30  ? 160 ASP D CB  1 
ATOM   10257 C  CG  . ASP D 2 162 ? 299.540 266.878 302.452 1.00 89.84  ? 160 ASP D CG  1 
ATOM   10258 O  OD1 . ASP D 2 162 ? 299.445 268.060 302.842 1.00 92.50  ? 160 ASP D OD1 1 
ATOM   10259 O  OD2 . ASP D 2 162 ? 299.132 265.904 303.119 1.00 91.10  ? 160 ASP D OD2 1 
ATOM   10260 N  N   . ILE D 2 163 ? 300.525 266.818 297.926 1.00 71.77  ? 161 ILE D N   1 
ATOM   10261 C  CA  . ILE D 2 163 ? 301.390 266.552 296.779 1.00 68.30  ? 161 ILE D CA  1 
ATOM   10262 C  C   . ILE D 2 163 ? 301.544 267.828 295.960 1.00 63.28  ? 161 ILE D C   1 
ATOM   10263 O  O   . ILE D 2 163 ? 300.541 268.418 295.533 1.00 65.73  ? 161 ILE D O   1 
ATOM   10264 C  CB  . ILE D 2 163 ? 300.840 265.404 295.920 1.00 64.46  ? 161 ILE D CB  1 
ATOM   10265 C  CG1 . ILE D 2 163 ? 300.669 264.143 296.767 1.00 66.70  ? 161 ILE D CG1 1 
ATOM   10266 C  CG2 . ILE D 2 163 ? 301.756 265.134 294.740 1.00 57.58  ? 161 ILE D CG2 1 
ATOM   10267 C  CD1 . ILE D 2 163 ? 299.775 263.102 296.138 1.00 69.01  ? 161 ILE D CD1 1 
ATOM   10268 N  N   . PRO D 2 164 ? 302.767 268.286 295.716 1.00 58.52  ? 162 PRO D N   1 
ATOM   10269 C  CA  . PRO D 2 164 ? 302.999 269.521 294.955 1.00 53.72  ? 162 PRO D CA  1 
ATOM   10270 C  C   . PRO D 2 164 ? 302.893 269.333 293.443 1.00 50.92  ? 162 PRO D C   1 
ATOM   10271 O  O   . PRO D 2 164 ? 303.777 269.734 292.685 1.00 54.84  ? 162 PRO D O   1 
ATOM   10272 C  CB  . PRO D 2 164 ? 304.416 269.922 295.378 1.00 54.82  ? 162 PRO D CB  1 
ATOM   10273 C  CG  . PRO D 2 164 ? 304.908 268.856 296.332 1.00 58.43  ? 162 PRO D CG  1 
ATOM   10274 C  CD  . PRO D 2 164 ? 304.021 267.679 296.179 1.00 59.44  ? 162 PRO D CD  1 
ATOM   10275 N  N   . SER D 2 165 ? 301.798 268.714 292.999 1.00 50.70  ? 163 SER D N   1 
ATOM   10276 C  CA  . SER D 2 165 ? 301.594 268.529 291.567 1.00 48.76  ? 163 SER D CA  1 
ATOM   10277 C  C   . SER D 2 165 ? 301.380 269.858 290.857 1.00 55.66  ? 163 SER D C   1 
ATOM   10278 O  O   . SER D 2 165 ? 301.693 269.980 289.667 1.00 56.53  ? 163 SER D O   1 
ATOM   10279 C  CB  . SER D 2 165 ? 300.408 267.599 291.320 1.00 47.83  ? 163 SER D CB  1 
ATOM   10280 O  OG  . SER D 2 165 ? 300.578 266.373 292.007 1.00 58.16  ? 163 SER D OG  1 
ATOM   10281 N  N   . ALA D 2 166 ? 300.850 270.856 291.560 1.00 55.85  ? 164 ALA D N   1 
ATOM   10282 C  CA  . ALA D 2 166 ? 300.651 272.183 290.995 1.00 52.02  ? 164 ALA D CA  1 
ATOM   10283 C  C   . ALA D 2 166 ? 301.785 273.143 291.312 1.00 53.94  ? 164 ALA D C   1 
ATOM   10284 O  O   . ALA D 2 166 ? 302.006 274.092 290.555 1.00 57.22  ? 164 ALA D O   1 
ATOM   10285 C  CB  . ALA D 2 166 ? 299.331 272.782 291.493 1.00 52.44  ? 164 ALA D CB  1 
ATOM   10286 N  N   . GLU D 2 167 ? 302.507 272.920 292.413 1.00 56.34  ? 165 GLU D N   1 
ATOM   10287 C  CA  . GLU D 2 167 ? 303.652 273.765 292.730 1.00 56.75  ? 165 GLU D CA  1 
ATOM   10288 C  C   . GLU D 2 167 ? 304.852 273.433 291.855 1.00 53.24  ? 165 GLU D C   1 
ATOM   10289 O  O   . GLU D 2 167 ? 305.636 274.327 291.517 1.00 58.43  ? 165 GLU D O   1 
ATOM   10290 C  CB  . GLU D 2 167 ? 304.021 273.622 294.206 1.00 62.78  ? 165 GLU D CB  1 
ATOM   10291 C  CG  . GLU D 2 167 ? 303.161 274.446 295.148 1.00 67.34  ? 165 GLU D CG  1 
ATOM   10292 C  CD  . GLU D 2 167 ? 301.727 273.963 295.202 1.00 73.45  ? 165 GLU D CD  1 
ATOM   10293 O  OE1 . GLU D 2 167 ? 301.501 272.747 295.027 1.00 70.55  ? 165 GLU D OE1 1 
ATOM   10294 O  OE2 . GLU D 2 167 ? 300.826 274.798 295.423 1.00 78.79  ? 165 GLU D OE2 1 
ATOM   10295 N  N   . VAL D 2 168 ? 305.016 272.166 291.483 1.00 53.47  ? 166 VAL D N   1 
ATOM   10296 C  CA  . VAL D 2 168 ? 306.076 271.780 290.558 1.00 53.09  ? 166 VAL D CA  1 
ATOM   10297 C  C   . VAL D 2 168 ? 305.751 272.401 289.205 1.00 51.04  ? 166 VAL D C   1 
ATOM   10298 O  O   . VAL D 2 168 ? 304.809 271.979 288.529 1.00 49.71  ? 166 VAL D O   1 
ATOM   10299 C  CB  . VAL D 2 168 ? 306.211 270.257 290.459 1.00 47.27  ? 166 VAL D CB  1 
ATOM   10300 C  CG1 . VAL D 2 168 ? 307.062 269.878 289.257 1.00 39.88  ? 166 VAL D CG1 1 
ATOM   10301 C  CG2 . VAL D 2 168 ? 306.805 269.698 291.742 1.00 46.47  ? 166 VAL D CG2 1 
ATOM   10302 N  N   . LYS D 2 169 ? 306.528 273.406 288.805 1.00 50.27  ? 167 LYS D N   1 
ATOM   10303 C  CA  . LYS D 2 169 ? 306.174 274.220 287.647 1.00 45.29  ? 167 LYS D CA  1 
ATOM   10304 C  C   . LYS D 2 169 ? 307.264 274.277 286.584 1.00 44.21  ? 167 LYS D C   1 
ATOM   10305 O  O   . LYS D 2 169 ? 307.108 275.001 285.594 1.00 47.27  ? 167 LYS D O   1 
ATOM   10306 C  CB  . LYS D 2 169 ? 305.806 275.638 288.091 1.00 53.50  ? 167 LYS D CB  1 
ATOM   10307 C  CG  . LYS D 2 169 ? 304.335 275.809 288.425 1.00 52.57  ? 167 LYS D CG  1 
ATOM   10308 C  CD  . LYS D 2 169 ? 304.131 276.744 289.602 1.00 55.92  ? 167 LYS D CD  1 
ATOM   10309 C  CE  . LYS D 2 169 ? 302.654 276.954 289.882 1.00 55.80  ? 167 LYS D CE  1 
ATOM   10310 N  NZ  . LYS D 2 169 ? 302.371 278.339 290.343 1.00 56.32  ? 167 LYS D NZ  1 
ATOM   10311 N  N   . ALA D 2 170 ? 308.354 273.536 286.752 1.00 46.91  ? 168 ALA D N   1 
ATOM   10312 C  CA  . ALA D 2 170 ? 309.398 273.491 285.743 1.00 40.57  ? 168 ALA D CA  1 
ATOM   10313 C  C   . ALA D 2 170 ? 310.079 272.135 285.805 1.00 37.95  ? 168 ALA D C   1 
ATOM   10314 O  O   . ALA D 2 170 ? 310.005 271.427 286.813 1.00 40.72  ? 168 ALA D O   1 
ATOM   10315 C  CB  . ALA D 2 170 ? 310.418 274.620 285.929 1.00 36.39  ? 168 ALA D CB  1 
ATOM   10316 N  N   . TYR D 2 171 ? 310.739 271.776 284.709 1.00 35.76  ? 169 TYR D N   1 
ATOM   10317 C  CA  . TYR D 2 171 ? 311.454 270.512 284.615 1.00 32.52  ? 169 TYR D CA  1 
ATOM   10318 C  C   . TYR D 2 171 ? 312.851 270.737 284.058 1.00 32.34  ? 169 TYR D C   1 
ATOM   10319 O  O   . TYR D 2 171 ? 313.078 271.641 283.252 1.00 34.76  ? 169 TYR D O   1 
ATOM   10320 C  CB  . TYR D 2 171 ? 310.711 269.503 283.727 1.00 35.40  ? 169 TYR D CB  1 
ATOM   10321 C  CG  . TYR D 2 171 ? 309.639 268.718 284.444 1.00 33.72  ? 169 TYR D CG  1 
ATOM   10322 C  CD1 . TYR D 2 171 ? 309.947 267.553 285.131 1.00 33.42  ? 169 TYR D CD1 1 
ATOM   10323 C  CD2 . TYR D 2 171 ? 308.318 269.139 284.429 1.00 33.28  ? 169 TYR D CD2 1 
ATOM   10324 C  CE1 . TYR D 2 171 ? 308.970 266.832 285.785 1.00 36.81  ? 169 TYR D CE1 1 
ATOM   10325 C  CE2 . TYR D 2 171 ? 307.337 268.427 285.080 1.00 32.60  ? 169 TYR D CE2 1 
ATOM   10326 C  CZ  . TYR D 2 171 ? 307.667 267.275 285.756 1.00 35.15  ? 169 TYR D CZ  1 
ATOM   10327 O  OH  . TYR D 2 171 ? 306.687 266.565 286.404 1.00 37.90  ? 169 TYR D OH  1 
ATOM   10328 N  N   . TYR D 2 172 ? 313.785 269.902 284.499 1.00 32.54  ? 170 TYR D N   1 
ATOM   10329 C  CA  . TYR D 2 172 ? 315.113 269.821 283.909 1.00 27.91  ? 170 TYR D CA  1 
ATOM   10330 C  C   . TYR D 2 172 ? 315.160 268.622 282.975 1.00 33.09  ? 170 TYR D C   1 
ATOM   10331 O  O   . TYR D 2 172 ? 314.826 267.504 283.378 1.00 37.77  ? 170 TYR D O   1 
ATOM   10332 C  CB  . TYR D 2 172 ? 316.194 269.688 284.982 1.00 31.71  ? 170 TYR D CB  1 
ATOM   10333 C  CG  . TYR D 2 172 ? 316.601 270.989 285.628 1.00 33.89  ? 170 TYR D CG  1 
ATOM   10334 C  CD1 . TYR D 2 172 ? 316.602 272.175 284.909 1.00 31.45  ? 170 TYR D CD1 1 
ATOM   10335 C  CD2 . TYR D 2 172 ? 316.994 271.029 286.957 1.00 33.18  ? 170 TYR D CD2 1 
ATOM   10336 C  CE1 . TYR D 2 172 ? 316.978 273.364 285.496 1.00 32.58  ? 170 TYR D CE1 1 
ATOM   10337 C  CE2 . TYR D 2 172 ? 317.369 272.212 287.553 1.00 36.36  ? 170 TYR D CE2 1 
ATOM   10338 C  CZ  . TYR D 2 172 ? 317.359 273.377 286.820 1.00 36.07  ? 170 TYR D CZ  1 
ATOM   10339 O  OH  . TYR D 2 172 ? 317.736 274.557 287.414 1.00 36.47  ? 170 TYR D OH  1 
ATOM   10340 N  N   . VAL D 2 173 ? 315.576 268.852 281.734 1.00 31.54  ? 171 VAL D N   1 
ATOM   10341 C  CA  . VAL D 2 173 ? 315.661 267.800 280.730 1.00 27.24  ? 171 VAL D CA  1 
ATOM   10342 C  C   . VAL D 2 173 ? 317.106 267.691 280.270 1.00 30.78  ? 171 VAL D C   1 
ATOM   10343 O  O   . VAL D 2 173 ? 317.701 268.682 279.833 1.00 32.80  ? 171 VAL D O   1 
ATOM   10344 C  CB  . VAL D 2 173 ? 314.726 268.071 279.539 1.00 33.20  ? 171 VAL D CB  1 
ATOM   10345 C  CG1 . VAL D 2 173 ? 314.582 266.823 278.687 1.00 30.03  ? 171 VAL D CG1 1 
ATOM   10346 C  CG2 . VAL D 2 173 ? 313.370 268.547 280.032 1.00 30.75  ? 171 VAL D CG2 1 
ATOM   10347 N  N   . LYS D 2 174 ? 317.665 266.490 280.367 1.00 30.25  ? 172 LYS D N   1 
ATOM   10348 C  CA  . LYS D 2 174 ? 319.039 266.220 279.957 1.00 25.84  ? 172 LYS D CA  1 
ATOM   10349 C  C   . LYS D 2 174 ? 318.997 265.516 278.605 1.00 27.14  ? 172 LYS D C   1 
ATOM   10350 O  O   . LYS D 2 174 ? 318.855 264.294 278.535 1.00 30.33  ? 172 LYS D O   1 
ATOM   10351 C  CB  . LYS D 2 174 ? 319.755 265.381 281.009 1.00 29.05  ? 172 LYS D CB  1 
ATOM   10352 C  CG  . LYS D 2 174 ? 321.244 265.221 280.774 1.00 28.90  ? 172 LYS D CG  1 
ATOM   10353 C  CD  . LYS D 2 174 ? 321.808 264.098 281.624 1.00 30.13  ? 172 LYS D CD  1 
ATOM   10354 C  CE  . LYS D 2 174 ? 323.305 264.249 281.816 1.00 31.80  ? 172 LYS D CE  1 
ATOM   10355 N  NZ  . LYS D 2 174 ? 323.971 262.938 282.039 1.00 33.72  ? 172 LYS D NZ  1 
ATOM   10356 N  N   . GLU D 2 175 ? 319.117 266.291 277.532 1.00 28.40  ? 173 GLU D N   1 
ATOM   10357 C  CA  . GLU D 2 175 ? 319.119 265.748 276.183 1.00 27.02  ? 173 GLU D CA  1 
ATOM   10358 C  C   . GLU D 2 175 ? 320.534 265.391 275.755 1.00 26.94  ? 173 GLU D C   1 
ATOM   10359 O  O   . GLU D 2 175 ? 321.512 265.996 276.200 1.00 30.72  ? 173 GLU D O   1 
ATOM   10360 C  CB  . GLU D 2 175 ? 318.545 266.749 275.181 1.00 29.22  ? 173 GLU D CB  1 
ATOM   10361 C  CG  . GLU D 2 175 ? 317.366 267.561 275.660 1.00 32.60  ? 173 GLU D CG  1 
ATOM   10362 C  CD  . GLU D 2 175 ? 316.980 268.627 274.656 1.00 40.48  ? 173 GLU D CD  1 
ATOM   10363 O  OE1 . GLU D 2 175 ? 317.892 269.216 274.041 1.00 36.74  ? 173 GLU D OE1 1 
ATOM   10364 O  OE2 . GLU D 2 175 ? 315.771 268.867 274.468 1.00 43.23  ? 173 GLU D OE2 1 
ATOM   10365 N  N   . GLU D 2 176 ? 320.630 264.413 274.861 1.00 32.00  ? 174 GLU D N   1 
ATOM   10366 C  CA  . GLU D 2 176 ? 321.883 264.050 274.213 1.00 28.44  ? 174 GLU D CA  1 
ATOM   10367 C  C   . GLU D 2 176 ? 321.637 264.052 272.713 1.00 27.94  ? 174 GLU D C   1 
ATOM   10368 O  O   . GLU D 2 176 ? 320.920 263.189 272.198 1.00 30.42  ? 174 GLU D O   1 
ATOM   10369 C  CB  . GLU D 2 176 ? 322.379 262.684 274.683 1.00 32.82  ? 174 GLU D CB  1 
ATOM   10370 C  CG  . GLU D 2 176 ? 323.478 262.099 273.818 1.00 31.86  ? 174 GLU D CG  1 
ATOM   10371 C  CD  . GLU D 2 176 ? 323.854 260.695 274.234 1.00 47.39  ? 174 GLU D CD  1 
ATOM   10372 O  OE1 . GLU D 2 176 ? 323.074 260.068 274.979 1.00 53.87  ? 174 GLU D OE1 1 
ATOM   10373 O  OE2 . GLU D 2 176 ? 324.926 260.214 273.813 1.00 48.20  ? 174 GLU D OE2 1 
ATOM   10374 N  N   . TRP D 2 177 ? 322.196 265.041 272.025 1.00 25.77  ? 175 TRP D N   1 
ATOM   10375 C  CA  . TRP D 2 177 ? 322.212 265.048 270.572 1.00 23.02  ? 175 TRP D CA  1 
ATOM   10376 C  C   . TRP D 2 177 ? 323.336 264.141 270.098 1.00 23.66  ? 175 TRP D C   1 
ATOM   10377 O  O   . TRP D 2 177 ? 324.459 264.219 270.606 1.00 30.38  ? 175 TRP D O   1 
ATOM   10378 C  CB  . TRP D 2 177 ? 322.420 266.465 270.038 1.00 23.94  ? 175 TRP D CB  1 
ATOM   10379 C  CG  . TRP D 2 177 ? 321.354 267.447 270.417 1.00 27.19  ? 175 TRP D CG  1 
ATOM   10380 C  CD1 . TRP D 2 177 ? 320.843 267.668 271.662 1.00 27.27  ? 175 TRP D CD1 1 
ATOM   10381 C  CD2 . TRP D 2 177 ? 320.691 268.367 269.544 1.00 29.27  ? 175 TRP D CD2 1 
ATOM   10382 N  NE1 . TRP D 2 177 ? 319.894 268.657 271.615 1.00 27.42  ? 175 TRP D NE1 1 
ATOM   10383 C  CE2 . TRP D 2 177 ? 319.782 269.103 270.325 1.00 26.99  ? 175 TRP D CE2 1 
ATOM   10384 C  CE3 . TRP D 2 177 ? 320.776 268.635 268.174 1.00 30.49  ? 175 TRP D CE3 1 
ATOM   10385 C  CZ2 . TRP D 2 177 ? 318.962 270.088 269.784 1.00 28.64  ? 175 TRP D CZ2 1 
ATOM   10386 C  CZ3 . TRP D 2 177 ? 319.961 269.614 267.639 1.00 30.84  ? 175 TRP D CZ3 1 
ATOM   10387 C  CH2 . TRP D 2 177 ? 319.066 270.328 268.442 1.00 29.76  ? 175 TRP D CH2 1 
ATOM   10388 N  N   . TYR D 2 178 ? 323.038 263.283 269.129 1.00 23.97  ? 176 TYR D N   1 
ATOM   10389 C  CA  . TYR D 2 178 ? 324.021 262.333 268.637 1.00 22.73  ? 176 TYR D CA  1 
ATOM   10390 C  C   . TYR D 2 178 ? 323.875 262.172 267.133 1.00 23.72  ? 176 TYR D C   1 
ATOM   10391 O  O   . TYR D 2 178 ? 322.819 262.437 266.550 1.00 23.77  ? 176 TYR D O   1 
ATOM   10392 C  CB  . TYR D 2 178 ? 323.893 260.970 269.334 1.00 26.25  ? 176 TYR D CB  1 
ATOM   10393 C  CG  . TYR D 2 178 ? 322.576 260.269 269.100 1.00 28.02  ? 176 TYR D CG  1 
ATOM   10394 C  CD1 . TYR D 2 178 ? 321.428 260.667 269.769 1.00 29.70  ? 176 TYR D CD1 1 
ATOM   10395 C  CD2 . TYR D 2 178 ? 322.483 259.202 268.219 1.00 29.01  ? 176 TYR D CD2 1 
ATOM   10396 C  CE1 . TYR D 2 178 ? 320.225 260.029 269.561 1.00 32.26  ? 176 TYR D CE1 1 
ATOM   10397 C  CE2 . TYR D 2 178 ? 321.283 258.557 268.004 1.00 32.38  ? 176 TYR D CE2 1 
ATOM   10398 C  CZ  . TYR D 2 178 ? 320.158 258.975 268.678 1.00 34.93  ? 176 TYR D CZ  1 
ATOM   10399 O  OH  . TYR D 2 178 ? 318.959 258.337 268.470 1.00 39.46  ? 176 TYR D OH  1 
ATOM   10400 N  N   . PHE D 2 179 ? 324.969 261.739 266.514 1.00 25.53  ? 177 PHE D N   1 
ATOM   10401 C  CA  . PHE D 2 179 ? 325.048 261.480 265.084 1.00 24.03  ? 177 PHE D CA  1 
ATOM   10402 C  C   . PHE D 2 179 ? 325.179 259.977 264.881 1.00 25.98  ? 177 PHE D C   1 
ATOM   10403 O  O   . PHE D 2 179 ? 326.178 259.378 265.293 1.00 31.20  ? 177 PHE D O   1 
ATOM   10404 C  CB  . PHE D 2 179 ? 326.235 262.225 264.471 1.00 20.58  ? 177 PHE D CB  1 
ATOM   10405 C  CG  . PHE D 2 179 ? 326.426 261.974 263.004 1.00 23.68  ? 177 PHE D CG  1 
ATOM   10406 C  CD1 . PHE D 2 179 ? 325.712 262.696 262.065 1.00 24.21  ? 177 PHE D CD1 1 
ATOM   10407 C  CD2 . PHE D 2 179 ? 327.332 261.025 262.565 1.00 25.43  ? 177 PHE D CD2 1 
ATOM   10408 C  CE1 . PHE D 2 179 ? 325.894 262.468 260.716 1.00 20.29  ? 177 PHE D CE1 1 
ATOM   10409 C  CE2 . PHE D 2 179 ? 327.515 260.794 261.221 1.00 20.36  ? 177 PHE D CE2 1 
ATOM   10410 C  CZ  . PHE D 2 179 ? 326.797 261.517 260.295 1.00 15.73  ? 177 PHE D CZ  1 
ATOM   10411 N  N   . THR D 2 180 ? 324.176 259.374 264.257 1.00 26.85  ? 178 THR D N   1 
ATOM   10412 C  CA  . THR D 2 180 ? 324.177 257.927 264.073 1.00 27.98  ? 178 THR D CA  1 
ATOM   10413 C  C   . THR D 2 180 ? 325.228 257.531 263.043 1.00 30.87  ? 178 THR D C   1 
ATOM   10414 O  O   . THR D 2 180 ? 325.276 258.117 261.956 1.00 35.33  ? 178 THR D O   1 
ATOM   10415 C  CB  . THR D 2 180 ? 322.800 257.438 263.629 1.00 32.01  ? 178 THR D CB  1 
ATOM   10416 O  OG1 . THR D 2 180 ? 321.823 257.798 264.613 1.00 33.02  ? 178 THR D OG1 1 
ATOM   10417 C  CG2 . THR D 2 180 ? 322.803 255.928 263.455 1.00 38.74  ? 178 THR D CG2 1 
ATOM   10418 N  N   . PRO D 2 181 ? 326.082 256.547 263.338 1.00 34.29  ? 179 PRO D N   1 
ATOM   10419 C  CA  . PRO D 2 181 ? 327.127 256.192 262.364 1.00 36.56  ? 179 PRO D CA  1 
ATOM   10420 C  C   . PRO D 2 181 ? 326.587 255.477 261.138 1.00 35.09  ? 179 PRO D C   1 
ATOM   10421 O  O   . PRO D 2 181 ? 327.005 255.787 260.016 1.00 42.88  ? 179 PRO D O   1 
ATOM   10422 C  CB  . PRO D 2 181 ? 328.071 255.298 263.179 1.00 33.96  ? 179 PRO D CB  1 
ATOM   10423 C  CG  . PRO D 2 181 ? 327.213 254.723 264.253 1.00 32.39  ? 179 PRO D CG  1 
ATOM   10424 C  CD  . PRO D 2 181 ? 326.175 255.758 264.578 1.00 30.19  ? 179 PRO D CD  1 
ATOM   10425 N  N   . THR D 2 182 ? 325.666 254.528 261.317 1.00 33.90  ? 180 THR D N   1 
ATOM   10426 C  CA  . THR D 2 182 ? 325.173 253.750 260.184 1.00 34.12  ? 180 THR D CA  1 
ATOM   10427 C  C   . THR D 2 182 ? 324.264 254.577 259.284 1.00 32.37  ? 180 THR D C   1 
ATOM   10428 O  O   . THR D 2 182 ? 324.290 254.424 258.058 1.00 34.84  ? 180 THR D O   1 
ATOM   10429 C  CB  . THR D 2 182 ? 324.429 252.510 260.677 1.00 35.48  ? 180 THR D CB  1 
ATOM   10430 O  OG1 . THR D 2 182 ? 323.329 252.909 261.502 1.00 42.99  ? 180 THR D OG1 1 
ATOM   10431 C  CG2 . THR D 2 182 ? 325.357 251.611 261.476 1.00 32.22  ? 180 THR D CG2 1 
ATOM   10432 N  N   . ASN D 2 183 ? 323.445 255.447 259.870 1.00 33.60  ? 181 ASN D N   1 
ATOM   10433 C  CA  . ASN D 2 183 ? 322.427 256.167 259.116 1.00 31.79  ? 181 ASN D CA  1 
ATOM   10434 C  C   . ASN D 2 183 ? 322.855 257.565 258.698 1.00 32.24  ? 181 ASN D C   1 
ATOM   10435 O  O   . ASN D 2 183 ? 322.339 258.083 257.703 1.00 33.67  ? 181 ASN D O   1 
ATOM   10436 C  CB  . ASN D 2 183 ? 321.136 256.265 259.935 1.00 31.92  ? 181 ASN D CB  1 
ATOM   10437 C  CG  . ASN D 2 183 ? 319.923 255.797 259.163 1.00 35.56  ? 181 ASN D CG  1 
ATOM   10438 O  OD1 . ASN D 2 183 ? 320.040 255.008 258.226 1.00 45.06  ? 181 ASN D OD1 1 
ATOM   10439 N  ND2 . ASN D 2 183 ? 318.751 256.286 259.544 1.00 39.68  ? 181 ASN D ND2 1 
ATOM   10440 N  N   . SER D 2 184 ? 323.778 258.189 259.431 1.00 30.78  ? 182 SER D N   1 
ATOM   10441 C  CA  . SER D 2 184 ? 324.250 259.538 259.116 1.00 26.33  ? 182 SER D CA  1 
ATOM   10442 C  C   . SER D 2 184 ? 323.140 260.573 259.315 1.00 27.98  ? 182 SER D C   1 
ATOM   10443 O  O   . SER D 2 184 ? 322.914 261.439 258.470 1.00 30.63  ? 182 SER D O   1 
ATOM   10444 C  CB  . SER D 2 184 ? 324.814 259.607 257.694 1.00 21.92  ? 182 SER D CB  1 
ATOM   10445 O  OG  . SER D 2 184 ? 326.175 259.221 257.660 1.00 33.36  ? 182 SER D OG  1 
ATOM   10446 N  N   . ASP D 2 185 ? 322.444 260.475 260.445 1.00 30.55  ? 183 ASP D N   1 
ATOM   10447 C  CA  . ASP D 2 185 ? 321.414 261.435 260.812 1.00 33.36  ? 183 ASP D CA  1 
ATOM   10448 C  C   . ASP D 2 185 ? 321.589 261.844 262.267 1.00 29.44  ? 183 ASP D C   1 
ATOM   10449 O  O   . ASP D 2 185 ? 322.195 261.130 263.069 1.00 29.66  ? 183 ASP D O   1 
ATOM   10450 C  CB  . ASP D 2 185 ? 319.999 260.879 260.592 1.00 33.49  ? 183 ASP D CB  1 
ATOM   10451 C  CG  . ASP D 2 185 ? 319.889 259.411 260.926 1.00 38.96  ? 183 ASP D CG  1 
ATOM   10452 O  OD1 . ASP D 2 185 ? 320.765 258.887 261.644 1.00 44.98  ? 183 ASP D OD1 1 
ATOM   10453 O  OD2 . ASP D 2 185 ? 318.918 258.778 260.467 1.00 44.29  ? 183 ASP D OD2 1 
ATOM   10454 N  N   . VAL D 2 186 ? 321.053 263.015 262.597 1.00 30.54  ? 184 VAL D N   1 
ATOM   10455 C  CA  . VAL D 2 186 ? 321.153 263.582 263.936 1.00 28.58  ? 184 VAL D CA  1 
ATOM   10456 C  C   . VAL D 2 186 ? 319.858 263.305 264.684 1.00 32.33  ? 184 VAL D C   1 
ATOM   10457 O  O   . VAL D 2 186 ? 318.763 263.518 264.148 1.00 32.51  ? 184 VAL D O   1 
ATOM   10458 C  CB  . VAL D 2 186 ? 321.444 265.090 263.883 1.00 27.46  ? 184 VAL D CB  1 
ATOM   10459 C  CG1 . VAL D 2 186 ? 321.476 265.669 265.285 1.00 27.81  ? 184 VAL D CG1 1 
ATOM   10460 C  CG2 . VAL D 2 186 ? 322.759 265.343 263.175 1.00 28.92  ? 184 VAL D CG2 1 
ATOM   10461 N  N   . ASP D 2 187 ? 319.980 262.825 265.919 1.00 31.50  ? 185 ASP D N   1 
ATOM   10462 C  CA  . ASP D 2 187 ? 318.819 262.559 266.754 1.00 27.18  ? 185 ASP D CA  1 
ATOM   10463 C  C   . ASP D 2 187 ? 319.085 263.057 268.167 1.00 28.10  ? 185 ASP D C   1 
ATOM   10464 O  O   . ASP D 2 187 ? 320.205 263.431 268.520 1.00 30.25  ? 185 ASP D O   1 
ATOM   10465 C  CB  . ASP D 2 187 ? 318.458 261.069 266.761 1.00 30.75  ? 185 ASP D CB  1 
ATOM   10466 C  CG  . ASP D 2 187 ? 316.960 260.834 266.761 1.00 37.68  ? 185 ASP D CG  1 
ATOM   10467 O  OD1 . ASP D 2 187 ? 316.203 261.814 266.923 1.00 38.46  ? 185 ASP D OD1 1 
ATOM   10468 O  OD2 . ASP D 2 187 ? 316.539 259.671 266.598 1.00 42.21  ? 185 ASP D OD2 1 
ATOM   10469 N  N   . ILE D 2 188 ? 318.026 263.071 268.974 1.00 30.84  ? 186 ILE D N   1 
ATOM   10470 C  CA  . ILE D 2 188 ? 318.083 263.504 270.365 1.00 29.15  ? 186 ILE D CA  1 
ATOM   10471 C  C   . ILE D 2 188 ? 317.524 262.389 271.236 1.00 29.18  ? 186 ILE D C   1 
ATOM   10472 O  O   . ILE D 2 188 ? 316.456 261.841 270.942 1.00 34.57  ? 186 ILE D O   1 
ATOM   10473 C  CB  . ILE D 2 188 ? 317.301 264.811 270.589 1.00 30.25  ? 186 ILE D CB  1 
ATOM   10474 C  CG1 . ILE D 2 188 ? 317.773 265.892 269.617 1.00 32.53  ? 186 ILE D CG1 1 
ATOM   10475 C  CG2 . ILE D 2 188 ? 317.456 265.289 272.023 1.00 28.20  ? 186 ILE D CG2 1 
ATOM   10476 C  CD1 . ILE D 2 188 ? 316.880 267.109 269.587 1.00 31.11  ? 186 ILE D CD1 1 
ATOM   10477 N  N   . LYS D 2 189 ? 318.243 262.057 272.303 1.00 28.37  ? 187 LYS D N   1 
ATOM   10478 C  CA  . LYS D 2 189 ? 317.825 261.045 273.263 1.00 26.89  ? 187 LYS D CA  1 
ATOM   10479 C  C   . LYS D 2 189 ? 317.721 261.682 274.640 1.00 30.81  ? 187 LYS D C   1 
ATOM   10480 O  O   . LYS D 2 189 ? 318.659 262.345 275.090 1.00 30.04  ? 187 LYS D O   1 
ATOM   10481 C  CB  . LYS D 2 189 ? 318.814 259.878 273.288 1.00 28.61  ? 187 LYS D CB  1 
ATOM   10482 C  CG  . LYS D 2 189 ? 318.339 258.663 274.059 1.00 32.88  ? 187 LYS D CG  1 
ATOM   10483 C  CD  . LYS D 2 189 ? 319.520 257.831 274.527 1.00 43.14  ? 187 LYS D CD  1 
ATOM   10484 C  CE  . LYS D 2 189 ? 319.098 256.760 275.515 1.00 45.23  ? 187 LYS D CE  1 
ATOM   10485 N  NZ  . LYS D 2 189 ? 318.409 255.625 274.844 1.00 44.46  ? 187 LYS D NZ  1 
ATOM   10486 N  N   . ILE D 2 190 ? 316.589 261.485 275.306 1.00 34.60  ? 188 ILE D N   1 
ATOM   10487 C  CA  . ILE D 2 190 ? 316.387 262.060 276.632 1.00 30.37  ? 188 ILE D CA  1 
ATOM   10488 C  C   . ILE D 2 190 ? 316.993 261.131 277.674 1.00 32.15  ? 188 ILE D C   1 
ATOM   10489 O  O   . ILE D 2 190 ? 316.677 259.937 277.721 1.00 34.94  ? 188 ILE D O   1 
ATOM   10490 C  CB  . ILE D 2 190 ? 314.894 262.303 276.903 1.00 31.20  ? 188 ILE D CB  1 
ATOM   10491 C  CG1 . ILE D 2 190 ? 314.432 263.598 276.235 1.00 34.03  ? 188 ILE D CG1 1 
ATOM   10492 C  CG2 . ILE D 2 190 ? 314.633 262.375 278.395 1.00 28.09  ? 188 ILE D CG2 1 
ATOM   10493 C  CD1 . ILE D 2 190 ? 314.080 263.443 274.781 1.00 35.96  ? 188 ILE D CD1 1 
ATOM   10494 N  N   . GLN D 2 191 ? 317.862 261.681 278.520 1.00 30.96  ? 189 GLN D N   1 
ATOM   10495 C  CA  . GLN D 2 191 ? 318.537 260.896 279.545 1.00 29.03  ? 189 GLN D CA  1 
ATOM   10496 C  C   . GLN D 2 191 ? 317.790 260.915 280.873 1.00 35.03  ? 189 GLN D C   1 
ATOM   10497 O  O   . GLN D 2 191 ? 317.554 259.860 281.469 1.00 43.00  ? 189 GLN D O   1 
ATOM   10498 C  CB  . GLN D 2 191 ? 319.965 261.410 279.742 1.00 32.14  ? 189 GLN D CB  1 
ATOM   10499 C  CG  . GLN D 2 191 ? 320.710 261.685 278.451 1.00 34.82  ? 189 GLN D CG  1 
ATOM   10500 C  CD  . GLN D 2 191 ? 321.671 260.574 278.090 1.00 45.27  ? 189 GLN D CD  1 
ATOM   10501 O  OE1 . GLN D 2 191 ? 321.263 259.440 277.839 1.00 47.99  ? 189 GLN D OE1 1 
ATOM   10502 N  NE2 . GLN D 2 191 ? 322.959 260.894 278.066 1.00 44.73  ? 189 GLN D NE2 1 
ATOM   10503 N  N   . ALA D 2 192 ? 317.415 262.099 281.351 1.00 33.62  ? 190 ALA D N   1 
ATOM   10504 C  CA  . ALA D 2 192 ? 316.779 262.219 282.653 1.00 33.58  ? 190 ALA D CA  1 
ATOM   10505 C  C   . ALA D 2 192 ? 315.956 263.496 282.702 1.00 34.28  ? 190 ALA D C   1 
ATOM   10506 O  O   . ALA D 2 192 ? 316.146 264.414 281.902 1.00 37.76  ? 190 ALA D O   1 
ATOM   10507 C  CB  . ALA D 2 192 ? 317.811 262.205 283.786 1.00 32.32  ? 190 ALA D CB  1 
ATOM   10508 N  N   . ILE D 2 193 ? 315.029 263.539 283.659 1.00 34.98  ? 191 ILE D N   1 
ATOM   10509 C  CA  . ILE D 2 193 ? 314.212 264.715 283.916 1.00 34.70  ? 191 ILE D CA  1 
ATOM   10510 C  C   . ILE D 2 193 ? 314.211 264.982 285.414 1.00 36.81  ? 191 ILE D C   1 
ATOM   10511 O  O   . ILE D 2 193 ? 314.437 264.086 286.230 1.00 37.24  ? 191 ILE D O   1 
ATOM   10512 C  CB  . ILE D 2 193 ? 312.769 264.555 283.392 1.00 36.05  ? 191 ILE D CB  1 
ATOM   10513 C  CG1 . ILE D 2 193 ? 312.049 263.434 284.140 1.00 37.79  ? 191 ILE D CG1 1 
ATOM   10514 C  CG2 . ILE D 2 193 ? 312.775 264.282 281.898 1.00 25.94  ? 191 ILE D CG2 1 
ATOM   10515 C  CD1 . ILE D 2 193 ? 310.545 263.490 284.020 1.00 31.48  ? 191 ILE D CD1 1 
ATOM   10516 N  N   . CYS D 2 194 ? 313.959 266.238 285.771 1.00 36.62  ? 192 CYS D N   1 
ATOM   10517 C  CA  . CYS D 2 194 ? 313.990 266.648 287.168 1.00 34.31  ? 192 CYS D CA  1 
ATOM   10518 C  C   . CYS D 2 194 ? 312.932 267.711 287.438 1.00 39.50  ? 192 CYS D C   1 
ATOM   10519 O  O   . CYS D 2 194 ? 313.037 268.834 286.930 1.00 42.97  ? 192 CYS D O   1 
ATOM   10520 C  CB  . CYS D 2 194 ? 315.378 267.170 287.540 1.00 31.93  ? 192 CYS D CB  1 
ATOM   10521 S  SG  . CYS D 2 194 ? 315.516 267.806 289.223 1.00 42.86  ? 192 CYS D SG  1 
ATOM   10522 N  N   . PRO D 2 195 ? 311.908 267.403 288.228 1.00 41.59  ? 193 PRO D N   1 
ATOM   10523 C  CA  . PRO D 2 195 ? 310.885 268.409 288.529 1.00 39.00  ? 193 PRO D CA  1 
ATOM   10524 C  C   . PRO D 2 195 ? 311.439 269.516 289.411 1.00 44.41  ? 193 PRO D C   1 
ATOM   10525 O  O   . PRO D 2 195 ? 312.348 269.306 290.217 1.00 47.05  ? 193 PRO D O   1 
ATOM   10526 C  CB  . PRO D 2 195 ? 309.794 267.612 289.258 1.00 37.81  ? 193 PRO D CB  1 
ATOM   10527 C  CG  . PRO D 2 195 ? 310.238 266.176 289.244 1.00 39.54  ? 193 PRO D CG  1 
ATOM   10528 C  CD  . PRO D 2 195 ? 311.702 266.160 288.985 1.00 39.53  ? 193 PRO D CD  1 
ATOM   10529 N  N   . ILE D 2 196 ? 310.871 270.707 289.253 1.00 45.10  ? 194 ILE D N   1 
ATOM   10530 C  CA  . ILE D 2 196 ? 311.287 271.883 290.008 1.00 46.56  ? 194 ILE D CA  1 
ATOM   10531 C  C   . ILE D 2 196 ? 310.070 272.436 290.738 1.00 53.22  ? 194 ILE D C   1 
ATOM   10532 O  O   . ILE D 2 196 ? 309.138 272.962 290.111 1.00 52.15  ? 194 ILE D O   1 
ATOM   10533 C  CB  . ILE D 2 196 ? 311.927 272.951 289.111 1.00 50.68  ? 194 ILE D CB  1 
ATOM   10534 C  CG1 . ILE D 2 196 ? 313.163 272.385 288.410 1.00 40.45  ? 194 ILE D CG1 1 
ATOM   10535 C  CG2 . ILE D 2 196 ? 312.296 274.176 289.927 1.00 53.84  ? 194 ILE D CG2 1 
ATOM   10536 C  CD1 . ILE D 2 196 ? 313.513 273.092 287.126 1.00 35.97  ? 194 ILE D CD1 1 
ATOM   10537 N  N   . MET D 2 197 ? 310.085 272.321 292.065 1.00 54.54  ? 195 MET D N   1 
ATOM   10538 C  CA  . MET D 2 197 ? 309.056 272.925 292.899 1.00 58.27  ? 195 MET D CA  1 
ATOM   10539 C  C   . MET D 2 197 ? 309.276 274.430 292.976 1.00 64.45  ? 195 MET D C   1 
ATOM   10540 O  O   . MET D 2 197 ? 310.391 274.892 293.234 1.00 67.04  ? 195 MET D O   1 
ATOM   10541 C  CB  . MET D 2 197 ? 309.087 272.313 294.298 1.00 61.55  ? 195 MET D CB  1 
ATOM   10542 C  CG  . MET D 2 197 ? 307.725 271.964 294.871 1.00 64.19  ? 195 MET D CG  1 
ATOM   10543 S  SD  . MET D 2 197 ? 307.776 271.859 296.669 1.00 84.36  ? 195 MET D SD  1 
ATOM   10544 C  CE  . MET D 2 197 ? 307.804 270.086 296.905 1.00 72.19  ? 195 MET D CE  1 
ATOM   10545 N  N   . THR D 2 198 ? 308.209 275.195 292.758 1.00 69.63  ? 196 THR D N   1 
ATOM   10546 C  CA  . THR D 2 198 ? 308.283 276.649 292.699 1.00 77.13  ? 196 THR D CA  1 
ATOM   10547 C  C   . THR D 2 198 ? 307.776 277.291 293.993 1.00 83.73  ? 196 THR D C   1 
ATOM   10548 O  O   . THR D 2 198 ? 307.352 278.450 294.006 1.00 83.98  ? 196 THR D O   1 
ATOM   10549 C  CB  . THR D 2 198 ? 307.517 277.139 291.463 1.00 73.22  ? 196 THR D CB  1 
ATOM   10550 O  OG1 . THR D 2 198 ? 308.322 276.916 290.299 1.00 66.23  ? 196 THR D OG1 1 
ATOM   10551 C  CG2 . THR D 2 198 ? 307.206 278.626 291.521 1.00 72.81  ? 196 THR D CG2 1 
ATOM   10552 N  N   . GLY D 2 199 ? 307.849 276.557 295.101 1.00 87.28  ? 197 GLY D N   1 
ATOM   10553 C  CA  . GLY D 2 199 ? 307.320 277.069 296.351 1.00 98.73  ? 197 GLY D CA  1 
ATOM   10554 C  C   . GLY D 2 199 ? 307.998 278.359 296.774 1.00 108.44 ? 197 GLY D C   1 
ATOM   10555 O  O   . GLY D 2 199 ? 309.161 278.615 296.456 1.00 109.28 ? 197 GLY D O   1 
ATOM   10556 N  N   . GLN D 2 200 ? 307.248 279.179 297.505 1.00 113.11 ? 198 GLN D N   1 
ATOM   10557 C  CA  . GLN D 2 200 ? 307.743 280.481 297.930 1.00 120.24 ? 198 GLN D CA  1 
ATOM   10558 C  C   . GLN D 2 200 ? 308.977 280.335 298.812 1.00 124.67 ? 198 GLN D C   1 
ATOM   10559 O  O   . GLN D 2 200 ? 309.105 279.378 299.581 1.00 125.67 ? 198 GLN D O   1 
ATOM   10560 C  CB  . GLN D 2 200 ? 306.652 281.238 298.688 1.00 123.34 ? 198 GLN D CB  1 
ATOM   10561 C  CG  . GLN D 2 200 ? 306.722 282.749 298.545 1.00 125.25 ? 198 GLN D CG  1 
ATOM   10562 C  CD  . GLN D 2 200 ? 306.109 283.239 297.250 1.00 125.59 ? 198 GLN D CD  1 
ATOM   10563 O  OE1 . GLN D 2 200 ? 306.770 283.893 296.443 1.00 125.13 ? 198 GLN D OE1 1 
ATOM   10564 N  NE2 . GLN D 2 200 ? 304.834 282.928 297.045 1.00 124.68 ? 198 GLN D NE2 1 
ATOM   10565 N  N   . ASP D 2 201 ? 309.889 281.295 298.693 1.00 125.45 ? 199 ASP D N   1 
ATOM   10566 C  CA  . ASP D 2 201 ? 311.079 281.323 299.529 1.00 127.96 ? 199 ASP D CA  1 
ATOM   10567 C  C   . ASP D 2 201 ? 310.750 281.914 300.893 1.00 133.20 ? 199 ASP D C   1 
ATOM   10568 O  O   . ASP D 2 201 ? 310.030 282.911 300.997 1.00 134.53 ? 199 ASP D O   1 
ATOM   10569 C  CB  . ASP D 2 201 ? 312.184 282.138 298.857 1.00 128.39 ? 199 ASP D CB  1 
ATOM   10570 C  CG  . ASP D 2 201 ? 313.553 281.867 299.450 1.00 126.80 ? 199 ASP D CG  1 
ATOM   10571 O  OD1 . ASP D 2 201 ? 313.627 281.212 300.511 1.00 125.32 ? 199 ASP D OD1 1 
ATOM   10572 O  OD2 . ASP D 2 201 ? 314.558 282.312 298.856 1.00 127.23 ? 199 ASP D OD2 1 
ATOM   10573 N  N   . GLU D 2 202 ? 311.280 281.289 301.942 1.00 133.92 ? 200 GLU D N   1 
ATOM   10574 C  CA  . GLU D 2 202 ? 311.072 281.800 303.289 1.00 136.04 ? 200 GLU D CA  1 
ATOM   10575 C  C   . GLU D 2 202 ? 311.670 283.194 303.420 1.00 139.76 ? 200 GLU D C   1 
ATOM   10576 O  O   . GLU D 2 202 ? 312.716 283.497 302.840 1.00 139.99 ? 200 GLU D O   1 
ATOM   10577 C  CB  . GLU D 2 202 ? 311.698 280.857 304.317 1.00 135.70 ? 200 GLU D CB  1 
ATOM   10578 C  CG  . GLU D 2 202 ? 310.965 279.537 304.471 1.00 138.22 ? 200 GLU D CG  1 
ATOM   10579 C  CD  . GLU D 2 202 ? 310.882 279.085 305.912 1.00 138.34 ? 200 GLU D CD  1 
ATOM   10580 O  OE1 . GLU D 2 202 ? 311.864 279.289 306.656 1.00 133.70 ? 200 GLU D OE1 1 
ATOM   10581 O  OE2 . GLU D 2 202 ? 309.834 278.528 306.303 1.00 141.08 ? 200 GLU D OE2 1 
ATOM   10582 N  N   . PHE D 2 203 ? 310.997 284.047 304.188 1.00 141.35 ? 201 PHE D N   1 
ATOM   10583 C  CA  . PHE D 2 203 ? 311.356 285.435 304.445 1.00 143.59 ? 201 PHE D CA  1 
ATOM   10584 C  C   . PHE D 2 203 ? 311.035 286.323 303.240 1.00 144.70 ? 201 PHE D C   1 
ATOM   10585 O  O   . PHE D 2 203 ? 311.078 287.548 303.367 1.00 144.40 ? 201 PHE D O   1 
ATOM   10586 C  CB  . PHE D 2 203 ? 312.839 285.600 304.842 1.00 143.69 ? 201 PHE D CB  1 
ATOM   10587 C  CG  . PHE D 2 203 ? 313.497 286.838 304.299 1.00 146.23 ? 201 PHE D CG  1 
ATOM   10588 C  CD1 . PHE D 2 203 ? 313.453 288.028 305.006 1.00 146.21 ? 201 PHE D CD1 1 
ATOM   10589 C  CD2 . PHE D 2 203 ? 314.168 286.809 303.086 1.00 143.51 ? 201 PHE D CD2 1 
ATOM   10590 C  CE1 . PHE D 2 203 ? 314.058 289.168 304.510 1.00 146.15 ? 201 PHE D CE1 1 
ATOM   10591 C  CE2 . PHE D 2 203 ? 314.775 287.945 302.586 1.00 141.78 ? 201 PHE D CE2 1 
ATOM   10592 C  CZ  . PHE D 2 203 ? 314.720 289.126 303.300 1.00 144.11 ? 201 PHE D CZ  1 
ATOM   10593 N  N   . GLY D 2 204 ? 310.648 285.756 302.103 1.00 142.24 ? 202 GLY D N   1 
ATOM   10594 C  CA  . GLY D 2 204 ? 310.337 286.510 300.909 1.00 138.77 ? 202 GLY D CA  1 
ATOM   10595 C  C   . GLY D 2 204 ? 311.019 285.927 299.693 1.00 137.60 ? 202 GLY D C   1 
ATOM   10596 O  O   . GLY D 2 204 ? 311.779 284.964 299.767 1.00 136.14 ? 202 GLY D O   1 
ATOM   10597 N  N   . GLU D 2 205 ? 310.726 286.535 298.543 1.00 135.75 ? 203 GLU D N   1 
ATOM   10598 C  CA  . GLU D 2 205 ? 311.315 286.102 297.282 1.00 133.91 ? 203 GLU D CA  1 
ATOM   10599 C  C   . GLU D 2 205 ? 310.831 284.709 296.901 1.00 131.77 ? 203 GLU D C   1 
ATOM   10600 O  O   . GLU D 2 205 ? 310.212 284.013 297.712 1.00 130.53 ? 203 GLU D O   1 
ATOM   10601 C  CB  . GLU D 2 205 ? 312.843 286.129 297.368 1.00 132.50 ? 203 GLU D CB  1 
ATOM   10602 C  CG  . GLU D 2 205 ? 313.543 286.141 296.020 1.00 132.83 ? 203 GLU D CG  1 
ATOM   10603 C  CD  . GLU D 2 205 ? 313.032 287.237 295.108 1.00 134.50 ? 203 GLU D CD  1 
ATOM   10604 O  OE1 . GLU D 2 205 ? 312.006 287.019 294.430 1.00 132.50 ? 203 GLU D OE1 1 
ATOM   10605 O  OE2 . GLU D 2 205 ? 313.657 288.317 295.068 1.00 133.80 ? 203 GLU D OE2 1 
ATOM   10606 N  N   . VAL D 2 206 ? 311.108 284.295 295.668 1.00 131.09 ? 204 VAL D N   1 
ATOM   10607 C  CA  . VAL D 2 206 ? 310.716 282.987 295.157 1.00 125.47 ? 204 VAL D CA  1 
ATOM   10608 C  C   . VAL D 2 206 ? 311.942 282.087 295.130 1.00 120.35 ? 204 VAL D C   1 
ATOM   10609 O  O   . VAL D 2 206 ? 313.038 282.524 294.757 1.00 119.16 ? 204 VAL D O   1 
ATOM   10610 C  CB  . VAL D 2 206 ? 310.084 283.095 293.756 1.00 122.60 ? 204 VAL D CB  1 
ATOM   10611 C  CG1 . VAL D 2 206 ? 309.002 284.164 293.745 1.00 123.33 ? 204 VAL D CG1 1 
ATOM   10612 C  CG2 . VAL D 2 206 ? 311.150 283.402 292.720 1.00 116.62 ? 204 VAL D CG2 1 
ATOM   10613 N  N   . ARG D 2 207 ? 311.759 280.833 295.536 1.00 114.37 ? 205 ARG D N   1 
ATOM   10614 C  CA  . ARG D 2 207 ? 312.835 279.851 295.554 1.00 106.13 ? 205 ARG D CA  1 
ATOM   10615 C  C   . ARG D 2 207 ? 312.403 278.625 294.764 1.00 93.06  ? 205 ARG D C   1 
ATOM   10616 O  O   . ARG D 2 207 ? 311.321 278.080 295.000 1.00 89.88  ? 205 ARG D O   1 
ATOM   10617 C  CB  . ARG D 2 207 ? 313.204 279.464 296.991 1.00 107.75 ? 205 ARG D CB  1 
ATOM   10618 C  CG  . ARG D 2 207 ? 314.475 278.640 297.106 1.00 102.65 ? 205 ARG D CG  1 
ATOM   10619 C  CD  . ARG D 2 207 ? 314.202 277.302 297.769 1.00 98.57  ? 205 ARG D CD  1 
ATOM   10620 N  NE  . ARG D 2 207 ? 313.256 277.427 298.871 1.00 106.24 ? 205 ARG D NE  1 
ATOM   10621 C  CZ  . ARG D 2 207 ? 313.581 277.325 300.153 1.00 107.93 ? 205 ARG D CZ  1 
ATOM   10622 N  NH1 . ARG D 2 207 ? 314.827 277.094 300.533 1.00 101.24 ? 205 ARG D NH1 1 
ATOM   10623 N  NH2 . ARG D 2 207 ? 312.633 277.457 301.076 1.00 110.82 ? 205 ARG D NH2 1 
ATOM   10624 N  N   . ASN D 2 208 ? 313.249 278.197 293.829 1.00 84.06  ? 206 ASN D N   1 
ATOM   10625 C  CA  . ASN D 2 208 ? 312.980 277.042 292.978 1.00 76.64  ? 206 ASN D CA  1 
ATOM   10626 C  C   . ASN D 2 208 ? 313.953 275.933 293.357 1.00 71.67  ? 206 ASN D C   1 
ATOM   10627 O  O   . ASN D 2 208 ? 315.162 276.058 293.133 1.00 69.81  ? 206 ASN D O   1 
ATOM   10628 C  CB  . ASN D 2 208 ? 313.116 277.412 291.503 1.00 75.06  ? 206 ASN D CB  1 
ATOM   10629 C  CG  . ASN D 2 208 ? 311.977 278.284 291.013 1.00 78.83  ? 206 ASN D CG  1 
ATOM   10630 O  OD1 . ASN D 2 208 ? 310.809 278.006 291.281 1.00 79.92  ? 206 ASN D OD1 1 
ATOM   10631 N  ND2 . ASN D 2 208 ? 312.312 279.344 290.290 1.00 73.78  ? 206 ASN D ND2 1 
ATOM   10632 N  N   . GLN D 2 209 ? 313.428 274.848 293.924 1.00 66.28  ? 207 GLN D N   1 
ATOM   10633 C  CA  . GLN D 2 209 ? 314.257 273.743 294.382 1.00 65.01  ? 207 GLN D CA  1 
ATOM   10634 C  C   . GLN D 2 209 ? 314.090 272.544 293.463 1.00 60.23  ? 207 GLN D C   1 
ATOM   10635 O  O   . GLN D 2 209 ? 312.988 271.982 293.388 1.00 57.03  ? 207 GLN D O   1 
ATOM   10636 C  CB  . GLN D 2 209 ? 313.901 273.356 295.815 1.00 71.33  ? 207 GLN D CB  1 
ATOM   10637 C  CG  . GLN D 2 209 ? 313.158 274.424 296.590 1.00 80.54  ? 207 GLN D CG  1 
ATOM   10638 C  CD  . GLN D 2 209 ? 312.941 274.033 298.034 1.00 84.99  ? 207 GLN D CD  1 
ATOM   10639 O  OE1 . GLN D 2 209 ? 313.896 273.827 298.782 1.00 86.67  ? 207 GLN D OE1 1 
ATOM   10640 N  NE2 . GLN D 2 209 ? 311.681 273.925 298.436 1.00 87.86  ? 207 GLN D NE2 1 
ATOM   10641 N  N   . PRO D 2 210 ? 315.131 272.121 292.747 1.00 60.23  ? 208 PRO D N   1 
ATOM   10642 C  CA  . PRO D 2 210 ? 315.056 270.838 292.040 1.00 56.28  ? 208 PRO D CA  1 
ATOM   10643 C  C   . PRO D 2 210 ? 314.861 269.700 293.030 1.00 55.98  ? 208 PRO D C   1 
ATOM   10644 O  O   . PRO D 2 210 ? 315.429 269.700 294.123 1.00 57.19  ? 208 PRO D O   1 
ATOM   10645 C  CB  . PRO D 2 210 ? 316.407 270.744 291.322 1.00 52.19  ? 208 PRO D CB  1 
ATOM   10646 C  CG  . PRO D 2 210 ? 316.942 272.141 291.306 1.00 49.60  ? 208 PRO D CG  1 
ATOM   10647 C  CD  . PRO D 2 210 ? 316.424 272.792 292.545 1.00 55.97  ? 208 PRO D CD  1 
ATOM   10648 N  N   . LEU D 2 211 ? 314.053 268.718 292.635 1.00 52.82  ? 209 LEU D N   1 
ATOM   10649 C  CA  . LEU D 2 211 ? 313.679 267.638 293.543 1.00 52.75  ? 209 LEU D CA  1 
ATOM   10650 C  C   . LEU D 2 211 ? 314.619 266.441 293.429 1.00 52.14  ? 209 LEU D C   1 
ATOM   10651 O  O   . LEU D 2 211 ? 315.265 266.055 294.408 1.00 52.66  ? 209 LEU D O   1 
ATOM   10652 C  CB  . LEU D 2 211 ? 312.230 267.213 293.279 1.00 51.16  ? 209 LEU D CB  1 
ATOM   10653 C  CG  . LEU D 2 211 ? 311.157 268.275 293.523 1.00 51.07  ? 209 LEU D CG  1 
ATOM   10654 C  CD1 . LEU D 2 211 ? 309.768 267.677 293.372 1.00 49.39  ? 209 LEU D CD1 1 
ATOM   10655 C  CD2 . LEU D 2 211 ? 311.328 268.907 294.895 1.00 56.22  ? 209 LEU D CD2 1 
ATOM   10656 N  N   . PHE D 2 212 ? 314.705 265.846 292.243 1.00 51.08  ? 210 PHE D N   1 
ATOM   10657 C  CA  . PHE D 2 212 ? 315.504 264.644 292.050 1.00 47.72  ? 210 PHE D CA  1 
ATOM   10658 C  C   . PHE D 2 212 ? 315.556 264.324 290.565 1.00 46.63  ? 210 PHE D C   1 
ATOM   10659 O  O   . PHE D 2 212 ? 314.766 264.844 289.772 1.00 49.51  ? 210 PHE D O   1 
ATOM   10660 C  CB  . PHE D 2 212 ? 314.937 263.460 292.839 1.00 49.73  ? 210 PHE D CB  1 
ATOM   10661 C  CG  . PHE D 2 212 ? 313.440 263.339 292.761 1.00 50.17  ? 210 PHE D CG  1 
ATOM   10662 C  CD1 . PHE D 2 212 ? 312.822 262.939 291.589 1.00 43.71  ? 210 PHE D CD1 1 
ATOM   10663 C  CD2 . PHE D 2 212 ? 312.653 263.624 293.862 1.00 50.64  ? 210 PHE D CD2 1 
ATOM   10664 C  CE1 . PHE D 2 212 ? 311.449 262.830 291.516 1.00 44.15  ? 210 PHE D CE1 1 
ATOM   10665 C  CE2 . PHE D 2 212 ? 311.278 263.517 293.796 1.00 50.05  ? 210 PHE D CE2 1 
ATOM   10666 C  CZ  . PHE D 2 212 ? 310.675 263.118 292.622 1.00 49.91  ? 210 PHE D CZ  1 
ATOM   10667 N  N   . TRP D 2 213 ? 316.494 263.455 290.202 1.00 43.65  ? 211 TRP D N   1 
ATOM   10668 C  CA  . TRP D 2 213 ? 316.686 263.037 288.821 1.00 40.56  ? 211 TRP D CA  1 
ATOM   10669 C  C   . TRP D 2 213 ? 315.973 261.715 288.580 1.00 41.63  ? 211 TRP D C   1 
ATOM   10670 O  O   . TRP D 2 213 ? 316.162 260.754 289.333 1.00 46.27  ? 211 TRP D O   1 
ATOM   10671 C  CB  . TRP D 2 213 ? 318.173 262.901 288.492 1.00 42.60  ? 211 TRP D CB  1 
ATOM   10672 C  CG  . TRP D 2 213 ? 318.851 264.208 288.250 1.00 41.29  ? 211 TRP D CG  1 
ATOM   10673 C  CD1 . TRP D 2 213 ? 319.714 264.849 289.086 1.00 41.90  ? 211 TRP D CD1 1 
ATOM   10674 C  CD2 . TRP D 2 213 ? 318.714 265.044 287.096 1.00 38.69  ? 211 TRP D CD2 1 
ATOM   10675 N  NE1 . TRP D 2 213 ? 320.129 266.030 288.524 1.00 44.67  ? 211 TRP D NE1 1 
ATOM   10676 C  CE2 . TRP D 2 213 ? 319.527 266.174 287.301 1.00 41.60  ? 211 TRP D CE2 1 
ATOM   10677 C  CE3 . TRP D 2 213 ? 317.984 264.946 285.909 1.00 37.22  ? 211 TRP D CE3 1 
ATOM   10678 C  CZ2 . TRP D 2 213 ? 319.631 267.197 286.364 1.00 38.93  ? 211 TRP D CZ2 1 
ATOM   10679 C  CZ3 . TRP D 2 213 ? 318.087 265.962 284.981 1.00 34.59  ? 211 TRP D CZ3 1 
ATOM   10680 C  CH2 . TRP D 2 213 ? 318.905 267.073 285.213 1.00 36.00  ? 211 TRP D CH2 1 
ATOM   10681 N  N   . ILE D 2 214 ? 315.157 261.671 287.534 1.00 39.43  ? 212 ILE D N   1 
ATOM   10682 C  CA  . ILE D 2 214 ? 314.444 260.469 287.123 1.00 36.38  ? 212 ILE D CA  1 
ATOM   10683 C  C   . ILE D 2 214 ? 315.087 259.970 285.831 1.00 40.26  ? 212 ILE D C   1 
ATOM   10684 O  O   . ILE D 2 214 ? 314.931 260.609 284.780 1.00 45.94  ? 212 ILE D O   1 
ATOM   10685 C  CB  . ILE D 2 214 ? 312.946 260.736 286.927 1.00 38.03  ? 212 ILE D CB  1 
ATOM   10686 C  CG1 . ILE D 2 214 ? 312.349 261.381 288.179 1.00 40.55  ? 212 ILE D CG1 1 
ATOM   10687 C  CG2 . ILE D 2 214 ? 312.216 259.448 286.578 1.00 38.61  ? 212 ILE D CG2 1 
ATOM   10688 C  CD1 . ILE D 2 214 ? 311.370 262.492 287.881 1.00 34.86  ? 212 ILE D CD1 1 
ATOM   10689 N  N   . PRO D 2 215 ? 315.821 258.860 285.852 1.00 40.78  ? 213 PRO D N   1 
ATOM   10690 C  CA  . PRO D 2 215 ? 316.308 258.289 284.591 1.00 38.38  ? 213 PRO D CA  1 
ATOM   10691 C  C   . PRO D 2 215 ? 315.138 257.978 283.670 1.00 39.06  ? 213 PRO D C   1 
ATOM   10692 O  O   . PRO D 2 215 ? 314.159 257.348 284.074 1.00 43.82  ? 213 PRO D O   1 
ATOM   10693 C  CB  . PRO D 2 215 ? 317.042 257.019 285.034 1.00 39.74  ? 213 PRO D CB  1 
ATOM   10694 C  CG  . PRO D 2 215 ? 317.374 257.248 286.468 1.00 41.58  ? 213 PRO D CG  1 
ATOM   10695 C  CD  . PRO D 2 215 ? 316.265 258.086 287.022 1.00 42.43  ? 213 PRO D CD  1 
ATOM   10696 N  N   . TYR D 2 216 ? 315.247 258.424 282.417 1.00 38.63  ? 214 TYR D N   1 
ATOM   10697 C  CA  . TYR D 2 216 ? 314.110 258.323 281.510 1.00 34.97  ? 214 TYR D CA  1 
ATOM   10698 C  C   . TYR D 2 216 ? 313.748 256.874 281.218 1.00 38.68  ? 214 TYR D C   1 
ATOM   10699 O  O   . TYR D 2 216 ? 312.573 256.561 281.004 1.00 42.27  ? 214 TYR D O   1 
ATOM   10700 C  CB  . TYR D 2 216 ? 314.396 259.076 280.212 1.00 31.63  ? 214 TYR D CB  1 
ATOM   10701 C  CG  . TYR D 2 216 ? 313.165 259.276 279.362 1.00 34.87  ? 214 TYR D CG  1 
ATOM   10702 C  CD1 . TYR D 2 216 ? 312.225 260.243 279.689 1.00 30.64  ? 214 TYR D CD1 1 
ATOM   10703 C  CD2 . TYR D 2 216 ? 312.936 258.493 278.241 1.00 34.18  ? 214 TYR D CD2 1 
ATOM   10704 C  CE1 . TYR D 2 216 ? 311.096 260.428 278.921 1.00 30.61  ? 214 TYR D CE1 1 
ATOM   10705 C  CE2 . TYR D 2 216 ? 311.810 258.670 277.467 1.00 34.20  ? 214 TYR D CE2 1 
ATOM   10706 C  CZ  . TYR D 2 216 ? 310.893 259.639 277.811 1.00 34.52  ? 214 TYR D CZ  1 
ATOM   10707 O  OH  . TYR D 2 216 ? 309.769 259.817 277.040 1.00 37.15  ? 214 TYR D OH  1 
ATOM   10708 N  N   . GLU D 2 217 ? 314.737 255.978 281.197 1.00 41.01  ? 215 GLU D N   1 
ATOM   10709 C  CA  . GLU D 2 217 ? 314.439 254.564 280.999 1.00 41.36  ? 215 GLU D CA  1 
ATOM   10710 C  C   . GLU D 2 217 ? 313.592 254.004 282.134 1.00 41.14  ? 215 GLU D C   1 
ATOM   10711 O  O   . GLU D 2 217 ? 312.839 253.045 281.933 1.00 43.23  ? 215 GLU D O   1 
ATOM   10712 C  CB  . GLU D 2 217 ? 315.737 253.768 280.861 1.00 42.84  ? 215 GLU D CB  1 
ATOM   10713 C  CG  . GLU D 2 217 ? 316.526 253.641 282.154 1.00 51.18  ? 215 GLU D CG  1 
ATOM   10714 C  CD  . GLU D 2 217 ? 317.747 254.538 282.186 1.00 60.25  ? 215 GLU D CD  1 
ATOM   10715 O  OE1 . GLU D 2 217 ? 317.623 255.729 281.829 1.00 54.66  ? 215 GLU D OE1 1 
ATOM   10716 O  OE2 . GLU D 2 217 ? 318.832 254.054 282.572 1.00 63.58  ? 215 GLU D OE2 1 
ATOM   10717 N  N   . ASN D 2 218 ? 313.701 254.583 283.331 1.00 38.88  ? 216 ASN D N   1 
ATOM   10718 C  CA  . ASN D 2 218 ? 312.930 254.089 284.467 1.00 40.08  ? 216 ASN D CA  1 
ATOM   10719 C  C   . ASN D 2 218 ? 311.456 254.456 284.344 1.00 42.01  ? 216 ASN D C   1 
ATOM   10720 O  O   . ASN D 2 218 ? 310.581 253.669 284.723 1.00 46.70  ? 216 ASN D O   1 
ATOM   10721 C  CB  . ASN D 2 218 ? 313.506 254.637 285.771 1.00 38.48  ? 216 ASN D CB  1 
ATOM   10722 C  CG  . ASN D 2 218 ? 314.861 254.051 286.101 1.00 44.10  ? 216 ASN D CG  1 
ATOM   10723 O  OD1 . ASN D 2 218 ? 315.507 253.434 285.255 1.00 45.65  ? 216 ASN D OD1 1 
ATOM   10724 N  ND2 . ASN D 2 218 ? 315.302 254.245 287.338 1.00 49.94  ? 216 ASN D ND2 1 
ATOM   10725 N  N   . ILE D 2 219 ? 311.161 255.649 283.826 1.00 40.95  ? 217 ILE D N   1 
ATOM   10726 C  CA  . ILE D 2 219 ? 309.789 256.142 283.760 1.00 39.59  ? 217 ILE D CA  1 
ATOM   10727 C  C   . ILE D 2 219 ? 309.136 255.908 282.404 1.00 40.82  ? 217 ILE D C   1 
ATOM   10728 O  O   . ILE D 2 219 ? 307.911 256.073 282.286 1.00 43.56  ? 217 ILE D O   1 
ATOM   10729 C  CB  . ILE D 2 219 ? 309.729 257.643 284.118 1.00 42.00  ? 217 ILE D CB  1 
ATOM   10730 C  CG1 . ILE D 2 219 ? 308.280 258.126 284.185 1.00 38.27  ? 217 ILE D CG1 1 
ATOM   10731 C  CG2 . ILE D 2 219 ? 310.532 258.464 283.122 1.00 38.64  ? 217 ILE D CG2 1 
ATOM   10732 C  CD1 . ILE D 2 219 ? 307.662 257.999 285.556 1.00 43.30  ? 217 ILE D CD1 1 
ATOM   10733 N  N   . ARG D 2 220 ? 309.900 255.517 281.385 1.00 41.08  ? 218 ARG D N   1 
ATOM   10734 C  CA  . ARG D 2 220 ? 309.334 255.392 280.044 1.00 44.51  ? 218 ARG D CA  1 
ATOM   10735 C  C   . ARG D 2 220 ? 308.163 254.422 279.984 1.00 49.96  ? 218 ARG D C   1 
ATOM   10736 O  O   . ARG D 2 220 ? 307.124 254.778 279.402 1.00 52.57  ? 218 ARG D O   1 
ATOM   10737 C  CB  . ARG D 2 220 ? 310.435 254.985 279.060 1.00 41.95  ? 218 ARG D CB  1 
ATOM   10738 C  CG  . ARG D 2 220 ? 310.111 255.285 277.609 1.00 41.69  ? 218 ARG D CG  1 
ATOM   10739 C  CD  . ARG D 2 220 ? 310.620 254.190 276.688 1.00 47.82  ? 218 ARG D CD  1 
ATOM   10740 N  NE  . ARG D 2 220 ? 309.608 253.170 276.443 1.00 60.44  ? 218 ARG D NE  1 
ATOM   10741 C  CZ  . ARG D 2 220 ? 309.557 251.998 277.061 1.00 62.52  ? 218 ARG D CZ  1 
ATOM   10742 N  NH1 . ARG D 2 220 ? 310.452 251.658 277.974 1.00 58.02  ? 218 ARG D NH1 1 
ATOM   10743 N  NH2 . ARG D 2 220 ? 308.582 251.146 276.757 1.00 50.39  ? 218 ARG D NH2 1 
ATOM   10744 N  N   . PRO D 2 221 ? 308.246 253.210 280.537 1.00 51.18  ? 219 PRO D N   1 
ATOM   10745 C  CA  . PRO D 2 221 ? 307.099 252.294 280.444 1.00 48.22  ? 219 PRO D CA  1 
ATOM   10746 C  C   . PRO D 2 221 ? 305.828 252.847 281.063 1.00 48.39  ? 219 PRO D C   1 
ATOM   10747 O  O   . PRO D 2 221 ? 304.732 252.570 280.560 1.00 49.82  ? 219 PRO D O   1 
ATOM   10748 C  CB  . PRO D 2 221 ? 307.590 251.040 281.184 1.00 46.62  ? 219 PRO D CB  1 
ATOM   10749 C  CG  . PRO D 2 221 ? 308.773 251.492 281.987 1.00 42.75  ? 219 PRO D CG  1 
ATOM   10750 C  CD  . PRO D 2 221 ? 309.404 252.578 281.187 1.00 45.61  ? 219 PRO D CD  1 
ATOM   10751 N  N   . TYR D 2 222 ? 305.938 253.622 282.142 1.00 48.48  ? 220 TYR D N   1 
ATOM   10752 C  CA  . TYR D 2 222 ? 304.750 254.109 282.834 1.00 46.86  ? 220 TYR D CA  1 
ATOM   10753 C  C   . TYR D 2 222 ? 304.086 255.263 282.094 1.00 49.41  ? 220 TYR D C   1 
ATOM   10754 O  O   . TYR D 2 222 ? 302.854 255.359 282.072 1.00 55.52  ? 220 TYR D O   1 
ATOM   10755 C  CB  . TYR D 2 222 ? 305.115 254.527 284.256 1.00 41.19  ? 220 TYR D CB  1 
ATOM   10756 C  CG  . TYR D 2 222 ? 305.739 253.416 285.064 1.00 49.33  ? 220 TYR D CG  1 
ATOM   10757 C  CD1 . TYR D 2 222 ? 305.033 252.254 285.343 1.00 49.44  ? 220 TYR D CD1 1 
ATOM   10758 C  CD2 . TYR D 2 222 ? 307.035 253.526 285.547 1.00 49.06  ? 220 TYR D CD2 1 
ATOM   10759 C  CE1 . TYR D 2 222 ? 305.599 251.236 286.081 1.00 51.47  ? 220 TYR D CE1 1 
ATOM   10760 C  CE2 . TYR D 2 222 ? 307.609 252.513 286.287 1.00 50.73  ? 220 TYR D CE2 1 
ATOM   10761 C  CZ  . TYR D 2 222 ? 306.887 251.371 286.551 1.00 55.90  ? 220 TYR D CZ  1 
ATOM   10762 O  OH  . TYR D 2 222 ? 307.456 250.359 287.288 1.00 64.10  ? 220 TYR D OH  1 
ATOM   10763 N  N   . ILE D 2 223 ? 304.878 256.149 281.481 1.00 43.87  ? 221 ILE D N   1 
ATOM   10764 C  CA  . ILE D 2 223 ? 304.323 257.318 280.806 1.00 43.83  ? 221 ILE D CA  1 
ATOM   10765 C  C   . ILE D 2 223 ? 303.970 257.044 279.353 1.00 44.99  ? 221 ILE D C   1 
ATOM   10766 O  O   . ILE D 2 223 ? 303.522 257.961 278.652 1.00 46.12  ? 221 ILE D O   1 
ATOM   10767 C  CB  . ILE D 2 223 ? 305.290 258.517 280.885 1.00 39.32  ? 221 ILE D CB  1 
ATOM   10768 C  CG1 . ILE D 2 223 ? 306.644 258.164 280.270 1.00 40.55  ? 221 ILE D CG1 1 
ATOM   10769 C  CG2 . ILE D 2 223 ? 305.450 258.974 282.323 1.00 38.06  ? 221 ILE D CG2 1 
ATOM   10770 C  CD1 . ILE D 2 223 ? 307.508 259.367 279.984 1.00 37.88  ? 221 ILE D CD1 1 
ATOM   10771 N  N   . ALA D 2 224 ? 304.156 255.817 278.877 1.00 45.26  ? 222 ALA D N   1 
ATOM   10772 C  CA  . ALA D 2 224 ? 303.751 255.440 277.532 1.00 49.27  ? 222 ALA D CA  1 
ATOM   10773 C  C   . ALA D 2 224 ? 302.311 254.954 277.470 1.00 53.02  ? 222 ALA D C   1 
ATOM   10774 O  O   . ALA D 2 224 ? 301.833 254.609 276.385 1.00 55.12  ? 222 ALA D O   1 
ATOM   10775 C  CB  . ALA D 2 224 ? 304.686 254.360 276.980 1.00 47.56  ? 222 ALA D CB  1 
ATOM   10776 N  N   . ARG D 2 225 ? 301.612 254.916 278.606 1.00 56.46  ? 223 ARG D N   1 
ATOM   10777 C  CA  . ARG D 2 225 ? 300.248 254.416 278.664 1.00 58.95  ? 223 ARG D CA  1 
ATOM   10778 C  C   . ARG D 2 225 ? 299.211 255.488 278.959 1.00 61.27  ? 223 ARG D C   1 
ATOM   10779 O  O   . ARG D 2 225 ? 298.034 255.283 278.649 1.00 58.49  ? 223 ARG D O   1 
ATOM   10780 C  CB  . ARG D 2 225 ? 300.135 253.313 279.727 1.00 61.57  ? 223 ARG D CB  1 
ATOM   10781 C  CG  . ARG D 2 225 ? 300.708 251.974 279.294 1.00 65.09  ? 223 ARG D CG  1 
ATOM   10782 C  CD  . ARG D 2 225 ? 300.297 250.861 280.244 1.00 70.66  ? 223 ARG D CD  1 
ATOM   10783 N  NE  . ARG D 2 225 ? 301.360 250.522 281.183 1.00 74.28  ? 223 ARG D NE  1 
ATOM   10784 C  CZ  . ARG D 2 225 ? 301.751 251.295 282.186 1.00 66.97  ? 223 ARG D CZ  1 
ATOM   10785 N  NH1 . ARG D 2 225 ? 301.186 252.469 282.416 1.00 64.77  ? 223 ARG D NH1 1 
ATOM   10786 N  NH2 . ARG D 2 225 ? 302.734 250.881 282.979 1.00 59.86  ? 223 ARG D NH2 1 
ATOM   10787 N  N   . GLU D 2 226 ? 299.610 256.617 279.539 1.00 63.93  ? 224 GLU D N   1 
ATOM   10788 C  CA  . GLU D 2 226 ? 298.675 257.669 279.925 1.00 66.18  ? 224 GLU D CA  1 
ATOM   10789 C  C   . GLU D 2 226 ? 298.528 258.654 278.770 1.00 58.73  ? 224 GLU D C   1 
ATOM   10790 O  O   . GLU D 2 226 ? 299.478 259.362 278.422 1.00 50.74  ? 224 GLU D O   1 
ATOM   10791 C  CB  . GLU D 2 226 ? 299.150 258.370 281.193 1.00 68.39  ? 224 GLU D CB  1 
ATOM   10792 C  CG  . GLU D 2 226 ? 298.986 257.538 282.457 1.00 77.25  ? 224 GLU D CG  1 
ATOM   10793 C  CD  . GLU D 2 226 ? 297.608 256.914 282.571 1.00 83.85  ? 224 GLU D CD  1 
ATOM   10794 O  OE1 . GLU D 2 226 ? 296.633 257.531 282.093 1.00 79.08  ? 224 GLU D OE1 1 
ATOM   10795 O  OE2 . GLU D 2 226 ? 297.498 255.806 283.138 1.00 82.34  ? 224 GLU D OE2 1 
ATOM   10796 N  N   . ARG D 2 227 ? 297.336 258.699 278.182 1.00 54.11  ? 225 ARG D N   1 
ATOM   10797 C  CA  . ARG D 2 227 ? 297.066 259.596 277.070 1.00 47.08  ? 225 ARG D CA  1 
ATOM   10798 C  C   . ARG D 2 227 ? 296.801 261.010 277.571 1.00 45.64  ? 225 ARG D C   1 
ATOM   10799 O  O   . ARG D 2 227 ? 296.165 261.210 278.609 1.00 48.69  ? 225 ARG D O   1 
ATOM   10800 C  CB  . ARG D 2 227 ? 295.871 259.096 276.261 1.00 46.77  ? 225 ARG D CB  1 
ATOM   10801 C  CG  . ARG D 2 227 ? 295.888 257.602 276.004 1.00 48.43  ? 225 ARG D CG  1 
ATOM   10802 C  CD  . ARG D 2 227 ? 295.490 257.282 274.577 1.00 52.49  ? 225 ARG D CD  1 
ATOM   10803 N  NE  . ARG D 2 227 ? 296.647 257.225 273.692 1.00 56.75  ? 225 ARG D NE  1 
ATOM   10804 C  CZ  . ARG D 2 227 ? 296.682 257.736 272.470 1.00 57.73  ? 225 ARG D CZ  1 
ATOM   10805 N  NH1 . ARG D 2 227 ? 295.635 258.354 271.948 1.00 56.16  ? 225 ARG D NH1 1 
ATOM   10806 N  NH2 . ARG D 2 227 ? 297.796 257.624 271.751 1.00 57.72  ? 225 ARG D NH2 1 
ATOM   10807 N  N   . VAL D 2 228 ? 297.298 261.993 276.823 1.00 45.89  ? 226 VAL D N   1 
ATOM   10808 C  CA  . VAL D 2 228 ? 297.154 263.399 277.162 1.00 41.47  ? 226 VAL D CA  1 
ATOM   10809 C  C   . VAL D 2 228 ? 296.718 264.157 275.914 1.00 40.58  ? 226 VAL D C   1 
ATOM   10810 O  O   . VAL D 2 228 ? 296.769 263.644 274.796 1.00 43.01  ? 226 VAL D O   1 
ATOM   10811 C  CB  . VAL D 2 228 ? 298.457 263.998 277.730 1.00 39.40  ? 226 VAL D CB  1 
ATOM   10812 C  CG1 . VAL D 2 228 ? 298.890 263.241 278.972 1.00 38.26  ? 226 VAL D CG1 1 
ATOM   10813 C  CG2 . VAL D 2 228 ? 299.553 263.967 276.678 1.00 36.55  ? 226 VAL D CG2 1 
ATOM   10814 N  N   . MET D 2 229 ? 296.278 265.392 276.122 1.00 37.62  ? 227 MET D N   1 
ATOM   10815 C  CA  . MET D 2 229 ? 295.954 266.297 275.030 1.00 39.58  ? 227 MET D CA  1 
ATOM   10816 C  C   . MET D 2 229 ? 297.085 267.303 274.862 1.00 41.20  ? 227 MET D C   1 
ATOM   10817 O  O   . MET D 2 229 ? 297.587 267.859 275.843 1.00 39.47  ? 227 MET D O   1 
ATOM   10818 C  CB  . MET D 2 229 ? 294.627 267.016 275.281 1.00 37.61  ? 227 MET D CB  1 
ATOM   10819 C  CG  . MET D 2 229 ? 294.727 268.238 276.175 1.00 37.36  ? 227 MET D CG  1 
ATOM   10820 S  SD  . MET D 2 229 ? 293.142 268.673 276.910 1.00 52.91  ? 227 MET D SD  1 
ATOM   10821 C  CE  . MET D 2 229 ? 293.586 270.132 277.845 1.00 39.04  ? 227 MET D CE  1 
ATOM   10822 N  N   . LEU D 2 230 ? 297.488 267.523 273.615 1.00 39.39  ? 228 LEU D N   1 
ATOM   10823 C  CA  . LEU D 2 230 ? 298.662 268.325 273.307 1.00 40.93  ? 228 LEU D CA  1 
ATOM   10824 C  C   . LEU D 2 230 ? 298.348 269.795 273.070 1.00 38.35  ? 228 LEU D C   1 
ATOM   10825 O  O   . LEU D 2 230 ? 299.261 270.561 272.752 1.00 40.48  ? 228 LEU D O   1 
ATOM   10826 C  CB  . LEU D 2 230 ? 299.376 267.759 272.076 1.00 41.65  ? 228 LEU D CB  1 
ATOM   10827 C  CG  . LEU D 2 230 ? 299.885 266.323 272.182 1.00 41.82  ? 228 LEU D CG  1 
ATOM   10828 C  CD1 . LEU D 2 230 ? 300.410 265.846 270.838 1.00 41.37  ? 228 LEU D CD1 1 
ATOM   10829 C  CD2 . LEU D 2 230 ? 300.956 266.215 273.253 1.00 39.47  ? 228 LEU D CD2 1 
ATOM   10830 N  N   . SER D 2 231 ? 297.094 270.210 273.217 1.00 35.27  ? 229 SER D N   1 
ATOM   10831 C  CA  . SER D 2 231 ? 296.724 271.578 272.896 1.00 34.44  ? 229 SER D CA  1 
ATOM   10832 C  C   . SER D 2 231 ? 295.519 271.990 273.724 1.00 34.82  ? 229 SER D C   1 
ATOM   10833 O  O   . SER D 2 231 ? 294.799 271.153 274.275 1.00 39.22  ? 229 SER D O   1 
ATOM   10834 C  CB  . SER D 2 231 ? 296.421 271.738 271.402 1.00 35.97  ? 229 SER D CB  1 
ATOM   10835 O  OG  . SER D 2 231 ? 296.468 273.099 271.012 1.00 39.60  ? 229 SER D OG  1 
ATOM   10836 N  N   . SER D 2 232 ? 295.316 273.302 273.812 1.00 37.95  ? 230 SER D N   1 
ATOM   10837 C  CA  . SER D 2 232 ? 294.106 273.850 274.405 1.00 37.92  ? 230 SER D CA  1 
ATOM   10838 C  C   . SER D 2 232 ? 292.987 274.002 273.387 1.00 36.00  ? 230 SER D C   1 
ATOM   10839 O  O   . SER D 2 232 ? 291.811 274.005 273.764 1.00 38.17  ? 230 SER D O   1 
ATOM   10840 C  CB  . SER D 2 232 ? 294.401 275.205 275.051 1.00 37.62  ? 230 SER D CB  1 
ATOM   10841 O  OG  . SER D 2 232 ? 295.243 275.059 276.180 1.00 40.17  ? 230 SER D OG  1 
ATOM   10842 N  N   . LEU D 2 233 ? 293.331 274.125 272.105 1.00 34.06  ? 231 LEU D N   1 
ATOM   10843 C  CA  . LEU D 2 233 ? 292.342 274.236 271.043 1.00 34.24  ? 231 LEU D CA  1 
ATOM   10844 C  C   . LEU D 2 233 ? 291.803 272.888 270.588 1.00 36.29  ? 231 LEU D C   1 
ATOM   10845 O  O   . LEU D 2 233 ? 290.801 272.850 269.867 1.00 42.99  ? 231 LEU D O   1 
ATOM   10846 C  CB  . LEU D 2 233 ? 292.942 274.976 269.846 1.00 36.37  ? 231 LEU D CB  1 
ATOM   10847 C  CG  . LEU D 2 233 ? 293.442 276.390 270.138 1.00 39.81  ? 231 LEU D CG  1 
ATOM   10848 C  CD1 . LEU D 2 233 ? 294.011 277.028 268.884 1.00 45.17  ? 231 LEU D CD1 1 
ATOM   10849 C  CD2 . LEU D 2 233 ? 292.326 277.238 270.719 1.00 36.40  ? 231 LEU D CD2 1 
ATOM   10850 N  N   . ASN D 2 234 ? 292.442 271.790 270.979 1.00 33.80  ? 232 ASN D N   1 
ATOM   10851 C  CA  . ASN D 2 234 ? 291.962 270.446 270.673 1.00 34.59  ? 232 ASN D CA  1 
ATOM   10852 C  C   . ASN D 2 234 ? 292.176 269.600 271.917 1.00 34.05  ? 232 ASN D C   1 
ATOM   10853 O  O   . ASN D 2 234 ? 293.318 269.309 272.283 1.00 40.78  ? 232 ASN D O   1 
ATOM   10854 C  CB  . ASN D 2 234 ? 292.688 269.849 269.467 1.00 36.10  ? 232 ASN D CB  1 
ATOM   10855 C  CG  . ASN D 2 234 ? 292.048 268.565 268.980 1.00 31.73  ? 232 ASN D CG  1 
ATOM   10856 O  OD1 . ASN D 2 234 ? 291.300 267.916 269.710 1.00 33.98  ? 232 ASN D OD1 1 
ATOM   10857 N  ND2 . ASN D 2 234 ? 292.343 268.188 267.743 1.00 31.82  ? 232 ASN D ND2 1 
ATOM   10858 N  N   . ASN D 2 235 ? 291.084 269.210 272.565 1.00 35.56  ? 233 ASN D N   1 
ATOM   10859 C  CA  . ASN D 2 235 ? 291.142 268.511 273.840 1.00 34.86  ? 233 ASN D CA  1 
ATOM   10860 C  C   . ASN D 2 235 ? 291.185 266.996 273.690 1.00 35.02  ? 233 ASN D C   1 
ATOM   10861 O  O   . ASN D 2 235 ? 291.164 266.290 274.702 1.00 39.25  ? 233 ASN D O   1 
ATOM   10862 C  CB  . ASN D 2 235 ? 289.948 268.913 274.710 1.00 34.54  ? 233 ASN D CB  1 
ATOM   10863 C  CG  . ASN D 2 235 ? 289.823 270.415 274.866 1.00 35.31  ? 233 ASN D CG  1 
ATOM   10864 O  OD1 . ASN D 2 235 ? 288.721 270.960 274.867 1.00 37.57  ? 233 ASN D OD1 1 
ATOM   10865 N  ND2 . ASN D 2 235 ? 290.956 271.093 275.000 1.00 36.58  ? 233 ASN D ND2 1 
ATOM   10866 N  N   . THR D 2 236 ? 291.241 266.481 272.466 1.00 34.48  ? 234 THR D N   1 
ATOM   10867 C  CA  . THR D 2 236 ? 291.360 265.043 272.276 1.00 36.12  ? 234 THR D CA  1 
ATOM   10868 C  C   . THR D 2 236 ? 292.662 264.537 272.885 1.00 38.17  ? 234 THR D C   1 
ATOM   10869 O  O   . THR D 2 236 ? 293.726 265.131 272.700 1.00 45.63  ? 234 THR D O   1 
ATOM   10870 C  CB  . THR D 2 236 ? 291.308 264.695 270.788 1.00 33.49  ? 234 THR D CB  1 
ATOM   10871 O  OG1 . THR D 2 236 ? 290.118 265.245 270.211 1.00 36.15  ? 234 THR D OG1 1 
ATOM   10872 C  CG2 . THR D 2 236 ? 291.306 263.189 270.595 1.00 37.36  ? 234 THR D CG2 1 
ATOM   10873 N  N   . ARG D 2 237 ? 292.572 263.431 273.619 1.00 34.82  ? 235 ARG D N   1 
ATOM   10874 C  CA  . ARG D 2 237 ? 293.742 262.828 274.255 1.00 38.60  ? 235 ARG D CA  1 
ATOM   10875 C  C   . ARG D 2 237 ? 294.321 261.751 273.338 1.00 38.71  ? 235 ARG D C   1 
ATOM   10876 O  O   . ARG D 2 237 ? 294.233 260.551 273.590 1.00 47.54  ? 235 ARG D O   1 
ATOM   10877 C  CB  . ARG D 2 237 ? 293.372 262.269 275.625 1.00 38.12  ? 235 ARG D CB  1 
ATOM   10878 C  CG  . ARG D 2 237 ? 292.981 263.330 276.636 1.00 41.09  ? 235 ARG D CG  1 
ATOM   10879 C  CD  . ARG D 2 237 ? 292.163 262.737 277.766 1.00 48.62  ? 235 ARG D CD  1 
ATOM   10880 N  NE  . ARG D 2 237 ? 292.949 261.833 278.596 1.00 51.59  ? 235 ARG D NE  1 
ATOM   10881 C  CZ  . ARG D 2 237 ? 292.481 261.202 279.664 1.00 59.79  ? 235 ARG D CZ  1 
ATOM   10882 N  NH1 . ARG D 2 237 ? 291.227 261.349 280.059 1.00 62.55  ? 235 ARG D NH1 1 
ATOM   10883 N  NH2 . ARG D 2 237 ? 293.292 260.404 280.352 1.00 57.14  ? 235 ARG D NH2 1 
ATOM   10884 N  N   . ASN D 2 238 ? 294.930 262.218 272.251 1.00 41.19  ? 236 ASN D N   1 
ATOM   10885 C  CA  . ASN D 2 238 ? 295.421 261.350 271.191 1.00 47.75  ? 236 ASN D CA  1 
ATOM   10886 C  C   . ASN D 2 238 ? 296.924 261.113 271.262 1.00 50.86  ? 236 ASN D C   1 
ATOM   10887 O  O   . ASN D 2 238 ? 297.498 260.577 270.310 1.00 53.89  ? 236 ASN D O   1 
ATOM   10888 C  CB  . ASN D 2 238 ? 295.054 261.925 269.819 1.00 46.59  ? 236 ASN D CB  1 
ATOM   10889 C  CG  . ASN D 2 238 ? 295.432 263.391 269.671 1.00 49.85  ? 236 ASN D CG  1 
ATOM   10890 O  OD1 . ASN D 2 238 ? 295.713 264.080 270.651 1.00 42.88  ? 236 ASN D OD1 1 
ATOM   10891 N  ND2 . ASN D 2 238 ? 295.438 263.872 268.434 1.00 56.49  ? 236 ASN D ND2 1 
ATOM   10892 N  N   . SER D 2 239 ? 297.573 261.490 272.361 1.00 48.90  ? 237 SER D N   1 
ATOM   10893 C  CA  . SER D 2 239 ? 299.014 261.343 272.497 1.00 43.32  ? 237 SER D CA  1 
ATOM   10894 C  C   . SER D 2 239 ? 299.334 260.868 273.907 1.00 39.75  ? 237 SER D C   1 
ATOM   10895 O  O   . SER D 2 239 ? 298.443 260.665 274.735 1.00 43.02  ? 237 SER D O   1 
ATOM   10896 C  CB  . SER D 2 239 ? 299.735 262.657 272.176 1.00 44.28  ? 237 SER D CB  1 
ATOM   10897 O  OG  . SER D 2 239 ? 301.064 262.417 271.750 1.00 50.59  ? 237 SER D OG  1 
ATOM   10898 N  N   . THR D 2 240 ? 300.623 260.682 274.175 1.00 38.84  ? 238 THR D N   1 
ATOM   10899 C  CA  . THR D 2 240 ? 301.113 260.289 275.486 1.00 37.37  ? 238 THR D CA  1 
ATOM   10900 C  C   . THR D 2 240 ? 302.283 261.185 275.870 1.00 37.72  ? 238 THR D C   1 
ATOM   10901 O  O   . THR D 2 240 ? 302.842 261.905 275.039 1.00 37.39  ? 238 THR D O   1 
ATOM   10902 C  CB  . THR D 2 240 ? 301.541 258.814 275.513 1.00 39.73  ? 238 THR D CB  1 
ATOM   10903 O  OG1 . THR D 2 240 ? 302.683 258.627 274.670 1.00 38.69  ? 238 THR D OG1 1 
ATOM   10904 C  CG2 . THR D 2 240 ? 300.415 257.925 275.022 1.00 43.13  ? 238 THR D CG2 1 
ATOM   10905 N  N   . ILE D 2 241 ? 302.645 261.146 277.153 1.00 38.44  ? 239 ILE D N   1 
ATOM   10906 C  CA  . ILE D 2 241 ? 303.816 261.887 277.611 1.00 33.32  ? 239 ILE D CA  1 
ATOM   10907 C  C   . ILE D 2 241 ? 305.067 261.381 276.905 1.00 35.28  ? 239 ILE D C   1 
ATOM   10908 O  O   . ILE D 2 241 ? 305.970 262.158 276.567 1.00 38.17  ? 239 ILE D O   1 
ATOM   10909 C  CB  . ILE D 2 241 ? 303.946 261.791 279.142 1.00 37.27  ? 239 ILE D CB  1 
ATOM   10910 C  CG1 . ILE D 2 241 ? 302.678 262.316 279.817 1.00 36.06  ? 239 ILE D CG1 1 
ATOM   10911 C  CG2 . ILE D 2 241 ? 305.170 262.551 279.626 1.00 36.89  ? 239 ILE D CG2 1 
ATOM   10912 C  CD1 . ILE D 2 241 ? 302.672 263.811 280.024 1.00 34.80  ? 239 ILE D CD1 1 
ATOM   10913 N  N   . ASP D 2 242 ? 305.140 260.068 276.672 1.00 38.10  ? 240 ASP D N   1 
ATOM   10914 C  CA  . ASP D 2 242 ? 306.276 259.507 275.952 1.00 37.05  ? 240 ASP D CA  1 
ATOM   10915 C  C   . ASP D 2 242 ? 306.374 260.082 274.545 1.00 34.21  ? 240 ASP D C   1 
ATOM   10916 O  O   . ASP D 2 242 ? 307.470 260.403 274.077 1.00 37.14  ? 240 ASP D O   1 
ATOM   10917 C  CB  . ASP D 2 242 ? 306.166 257.983 275.904 1.00 39.52  ? 240 ASP D CB  1 
ATOM   10918 C  CG  . ASP D 2 242 ? 307.411 257.327 275.348 1.00 48.89  ? 240 ASP D CG  1 
ATOM   10919 O  OD1 . ASP D 2 242 ? 308.511 257.597 275.869 1.00 49.67  ? 240 ASP D OD1 1 
ATOM   10920 O  OD2 . ASP D 2 242 ? 307.289 256.540 274.387 1.00 55.90  ? 240 ASP D OD2 1 
ATOM   10921 N  N   . ASP D 2 243 ? 305.242 260.207 273.849 1.00 37.27  ? 241 ASP D N   1 
ATOM   10922 C  CA  . ASP D 2 243 ? 305.254 260.837 272.532 1.00 35.90  ? 241 ASP D CA  1 
ATOM   10923 C  C   . ASP D 2 243 ? 305.663 262.299 272.629 1.00 36.33  ? 241 ASP D C   1 
ATOM   10924 O  O   . ASP D 2 243 ? 306.389 262.810 271.769 1.00 37.46  ? 241 ASP D O   1 
ATOM   10925 C  CB  . ASP D 2 243 ? 303.883 260.712 271.871 1.00 37.08  ? 241 ASP D CB  1 
ATOM   10926 C  CG  . ASP D 2 243 ? 303.536 259.284 271.519 1.00 44.49  ? 241 ASP D CG  1 
ATOM   10927 O  OD1 . ASP D 2 243 ? 304.415 258.569 270.996 1.00 47.23  ? 241 ASP D OD1 1 
ATOM   10928 O  OD2 . ASP D 2 243 ? 302.381 258.877 271.761 1.00 52.66  ? 241 ASP D OD2 1 
ATOM   10929 N  N   . PHE D 2 244 ? 305.192 262.992 273.666 1.00 36.11  ? 242 PHE D N   1 
ATOM   10930 C  CA  . PHE D 2 244 ? 305.549 264.393 273.846 1.00 32.33  ? 242 PHE D CA  1 
ATOM   10931 C  C   . PHE D 2 244 ? 307.056 264.562 273.988 1.00 32.93  ? 242 PHE D C   1 
ATOM   10932 O  O   . PHE D 2 244 ? 307.641 265.487 273.415 1.00 34.79  ? 242 PHE D O   1 
ATOM   10933 C  CB  . PHE D 2 244 ? 304.816 264.952 275.066 1.00 34.88  ? 242 PHE D CB  1 
ATOM   10934 C  CG  . PHE D 2 244 ? 305.240 266.336 275.457 1.00 34.32  ? 242 PHE D CG  1 
ATOM   10935 C  CD1 . PHE D 2 244 ? 304.694 267.444 274.833 1.00 28.34  ? 242 PHE D CD1 1 
ATOM   10936 C  CD2 . PHE D 2 244 ? 306.173 266.531 276.461 1.00 33.46  ? 242 PHE D CD2 1 
ATOM   10937 C  CE1 . PHE D 2 244 ? 305.078 268.715 275.195 1.00 29.07  ? 242 PHE D CE1 1 
ATOM   10938 C  CE2 . PHE D 2 244 ? 306.560 267.801 276.826 1.00 32.68  ? 242 PHE D CE2 1 
ATOM   10939 C  CZ  . PHE D 2 244 ? 306.011 268.895 276.192 1.00 33.41  ? 242 PHE D CZ  1 
ATOM   10940 N  N   . PHE D 2 245 ? 307.703 263.679 274.751 1.00 34.67  ? 243 PHE D N   1 
ATOM   10941 C  CA  . PHE D 2 245 ? 309.150 263.776 274.912 1.00 31.98  ? 243 PHE D CA  1 
ATOM   10942 C  C   . PHE D 2 245 ? 309.899 263.299 273.671 1.00 32.75  ? 243 PHE D C   1 
ATOM   10943 O  O   . PHE D 2 245 ? 310.893 263.915 273.272 1.00 36.08  ? 243 PHE D O   1 
ATOM   10944 C  CB  . PHE D 2 245 ? 309.599 262.986 276.141 1.00 27.97  ? 243 PHE D CB  1 
ATOM   10945 C  CG  . PHE D 2 245 ? 309.490 263.755 277.422 1.00 31.94  ? 243 PHE D CG  1 
ATOM   10946 C  CD1 . PHE D 2 245 ? 310.218 264.917 277.608 1.00 32.55  ? 243 PHE D CD1 1 
ATOM   10947 C  CD2 . PHE D 2 245 ? 308.660 263.321 278.439 1.00 30.60  ? 243 PHE D CD2 1 
ATOM   10948 C  CE1 . PHE D 2 245 ? 310.120 265.629 278.784 1.00 31.33  ? 243 PHE D CE1 1 
ATOM   10949 C  CE2 . PHE D 2 245 ? 308.559 264.030 279.616 1.00 28.08  ? 243 PHE D CE2 1 
ATOM   10950 C  CZ  . PHE D 2 245 ? 309.289 265.185 279.789 1.00 31.24  ? 243 PHE D CZ  1 
ATOM   10951 N  N   . ARG D 2 246 ? 309.441 262.211 273.048 1.00 32.10  ? 244 ARG D N   1 
ATOM   10952 C  CA  . ARG D 2 246 ? 310.150 261.654 271.901 1.00 30.37  ? 244 ARG D CA  1 
ATOM   10953 C  C   . ARG D 2 246 ? 310.024 262.539 270.670 1.00 34.76  ? 244 ARG D C   1 
ATOM   10954 O  O   . ARG D 2 246 ? 310.909 262.526 269.808 1.00 36.56  ? 244 ARG D O   1 
ATOM   10955 C  CB  . ARG D 2 246 ? 309.632 260.249 271.594 1.00 28.61  ? 244 ARG D CB  1 
ATOM   10956 C  CG  . ARG D 2 246 ? 310.297 259.585 270.400 1.00 31.18  ? 244 ARG D CG  1 
ATOM   10957 C  CD  . ARG D 2 246 ? 311.678 259.060 270.755 1.00 33.40  ? 244 ARG D CD  1 
ATOM   10958 N  NE  . ARG D 2 246 ? 312.315 258.380 269.633 1.00 30.12  ? 244 ARG D NE  1 
ATOM   10959 C  CZ  . ARG D 2 246 ? 313.061 258.980 268.716 1.00 30.02  ? 244 ARG D CZ  1 
ATOM   10960 N  NH1 . ARG D 2 246 ? 313.288 260.282 268.754 1.00 30.41  ? 244 ARG D NH1 1 
ATOM   10961 N  NH2 . ARG D 2 246 ? 313.594 258.255 267.738 1.00 29.55  ? 244 ARG D NH2 1 
ATOM   10962 N  N   . LEU D 2 247 ? 308.941 263.302 270.561 1.00 36.59  ? 245 LEU D N   1 
ATOM   10963 C  CA  . LEU D 2 247 ? 308.756 264.231 269.456 1.00 33.02  ? 245 LEU D CA  1 
ATOM   10964 C  C   . LEU D 2 247 ? 309.430 265.572 269.700 1.00 33.76  ? 245 LEU D C   1 
ATOM   10965 O  O   . LEU D 2 247 ? 309.424 266.424 268.806 1.00 42.45  ? 245 LEU D O   1 
ATOM   10966 C  CB  . LEU D 2 247 ? 307.264 264.447 269.189 1.00 34.99  ? 245 LEU D CB  1 
ATOM   10967 C  CG  . LEU D 2 247 ? 306.491 263.249 268.638 1.00 37.33  ? 245 LEU D CG  1 
ATOM   10968 C  CD1 . LEU D 2 247 ? 304.996 263.518 268.659 1.00 35.11  ? 245 LEU D CD1 1 
ATOM   10969 C  CD2 . LEU D 2 247 ? 306.956 262.917 267.231 1.00 38.13  ? 245 LEU D CD2 1 
ATOM   10970 N  N   . ASN D 2 248 ? 310.009 265.777 270.881 1.00 30.47  ? 246 ASN D N   1 
ATOM   10971 C  CA  . ASN D 2 248 ? 310.668 267.033 271.228 1.00 32.72  ? 246 ASN D CA  1 
ATOM   10972 C  C   . ASN D 2 248 ? 309.703 268.209 271.095 1.00 33.40  ? 246 ASN D C   1 
ATOM   10973 O  O   . ASN D 2 248 ? 310.031 269.255 270.532 1.00 35.76  ? 246 ASN D O   1 
ATOM   10974 C  CB  . ASN D 2 248 ? 311.922 267.246 270.377 1.00 35.34  ? 246 ASN D CB  1 
ATOM   10975 C  CG  . ASN D 2 248 ? 312.949 266.150 270.574 1.00 43.88  ? 246 ASN D CG  1 
ATOM   10976 O  OD1 . ASN D 2 248 ? 313.201 265.349 269.673 1.00 47.39  ? 246 ASN D OD1 1 
ATOM   10977 N  ND2 . ASN D 2 248 ? 313.540 266.101 271.761 1.00 37.73  ? 246 ASN D ND2 1 
ATOM   10978 N  N   . LEU D 2 249 ? 308.494 268.027 271.625 1.00 32.22  ? 247 LEU D N   1 
ATOM   10979 C  CA  . LEU D 2 249 ? 307.483 269.074 271.586 1.00 31.71  ? 247 LEU D CA  1 
ATOM   10980 C  C   . LEU D 2 249 ? 307.666 270.113 272.683 1.00 34.34  ? 247 LEU D C   1 
ATOM   10981 O  O   . LEU D 2 249 ? 307.031 271.171 272.623 1.00 36.83  ? 247 LEU D O   1 
ATOM   10982 C  CB  . LEU D 2 249 ? 306.087 268.459 271.689 1.00 30.48  ? 247 LEU D CB  1 
ATOM   10983 C  CG  . LEU D 2 249 ? 305.666 267.587 270.505 1.00 33.33  ? 247 LEU D CG  1 
ATOM   10984 C  CD1 . LEU D 2 249 ? 304.282 266.999 270.731 1.00 33.49  ? 247 LEU D CD1 1 
ATOM   10985 C  CD2 . LEU D 2 249 ? 305.716 268.380 269.208 1.00 31.87  ? 247 LEU D CD2 1 
ATOM   10986 N  N   . TYR D 2 250 ? 308.508 269.839 273.672 1.00 36.26  ? 248 TYR D N   1 
ATOM   10987 C  CA  . TYR D 2 250 ? 308.775 270.793 274.735 1.00 32.94  ? 248 TYR D CA  1 
ATOM   10988 C  C   . TYR D 2 250 ? 309.711 271.893 274.250 1.00 38.48  ? 248 TYR D C   1 
ATOM   10989 O  O   . TYR D 2 250 ? 310.546 271.687 273.365 1.00 37.34  ? 248 TYR D O   1 
ATOM   10990 C  CB  . TYR D 2 250 ? 309.382 270.086 275.946 1.00 30.05  ? 248 TYR D CB  1 
ATOM   10991 C  CG  . TYR D 2 250 ? 310.611 269.277 275.616 1.00 36.37  ? 248 TYR D CG  1 
ATOM   10992 C  CD1 . TYR D 2 250 ? 310.501 267.970 275.163 1.00 33.60  ? 248 TYR D CD1 1 
ATOM   10993 C  CD2 . TYR D 2 250 ? 311.881 269.818 275.753 1.00 35.02  ? 248 TYR D CD2 1 
ATOM   10994 C  CE1 . TYR D 2 250 ? 311.618 267.226 274.856 1.00 32.29  ? 248 TYR D CE1 1 
ATOM   10995 C  CE2 . TYR D 2 250 ? 313.004 269.081 275.449 1.00 36.64  ? 248 TYR D CE2 1 
ATOM   10996 C  CZ  . TYR D 2 250 ? 312.866 267.785 275.002 1.00 35.14  ? 248 TYR D CZ  1 
ATOM   10997 O  OH  . TYR D 2 250 ? 313.981 267.042 274.697 1.00 37.63  ? 248 TYR D OH  1 
ATOM   10998 N  N   . LYS D 2 251 ? 309.561 273.074 274.843 1.00 39.85  ? 249 LYS D N   1 
ATOM   10999 C  CA  . LYS D 2 251 ? 310.379 274.239 274.520 1.00 34.22  ? 249 LYS D CA  1 
ATOM   11000 C  C   . LYS D 2 251 ? 311.051 274.718 275.799 1.00 32.31  ? 249 LYS D C   1 
ATOM   11001 O  O   . LYS D 2 251 ? 310.379 275.195 276.718 1.00 40.93  ? 249 LYS D O   1 
ATOM   11002 C  CB  . LYS D 2 251 ? 309.535 275.347 273.893 1.00 39.05  ? 249 LYS D CB  1 
ATOM   11003 C  CG  . LYS D 2 251 ? 308.959 275.000 272.530 1.00 45.39  ? 249 LYS D CG  1 
ATOM   11004 C  CD  . LYS D 2 251 ? 310.000 275.171 271.437 1.00 48.27  ? 249 LYS D CD  1 
ATOM   11005 C  CE  . LYS D 2 251 ? 309.728 274.247 270.265 1.00 48.55  ? 249 LYS D CE  1 
ATOM   11006 N  NZ  . LYS D 2 251 ? 309.362 272.878 270.712 1.00 44.61  ? 249 LYS D NZ  1 
ATOM   11007 N  N   . GLY D 2 252 ? 312.378 274.594 275.856 1.00 35.13  ? 250 GLY D N   1 
ATOM   11008 C  CA  . GLY D 2 252 ? 313.130 275.008 277.017 1.00 32.47  ? 250 GLY D CA  1 
ATOM   11009 C  C   . GLY D 2 252 ? 314.348 275.821 276.618 1.00 34.92  ? 250 GLY D C   1 
ATOM   11010 O  O   . GLY D 2 252 ? 314.749 275.857 275.453 1.00 39.31  ? 250 GLY D O   1 
ATOM   11011 N  N   . ASP D 2 253 ? 314.930 276.476 277.616 1.00 32.48  ? 251 ASP D N   1 
ATOM   11012 C  CA  . ASP D 2 253 ? 316.139 277.264 277.435 1.00 31.24  ? 251 ASP D CA  1 
ATOM   11013 C  C   . ASP D 2 253 ? 317.326 276.474 277.965 1.00 30.38  ? 251 ASP D C   1 
ATOM   11014 O  O   . ASP D 2 253 ? 317.264 275.917 279.065 1.00 33.00  ? 251 ASP D O   1 
ATOM   11015 C  CB  . ASP D 2 253 ? 316.029 278.609 278.155 1.00 35.08  ? 251 ASP D CB  1 
ATOM   11016 C  CG  . ASP D 2 253 ? 315.497 279.708 277.257 1.00 49.44  ? 251 ASP D CG  1 
ATOM   11017 O  OD1 . ASP D 2 253 ? 316.164 280.036 276.254 1.00 55.30  ? 251 ASP D OD1 1 
ATOM   11018 O  OD2 . ASP D 2 253 ? 314.409 280.245 277.554 1.00 53.47  ? 251 ASP D OD2 1 
ATOM   11019 N  N   . ILE D 2 254 ? 318.399 276.416 277.177 1.00 30.93  ? 252 ILE D N   1 
ATOM   11020 C  CA  . ILE D 2 254 ? 319.587 275.694 277.610 1.00 28.64  ? 252 ILE D CA  1 
ATOM   11021 C  C   . ILE D 2 254 ? 320.137 276.364 278.858 1.00 29.90  ? 252 ILE D C   1 
ATOM   11022 O  O   . ILE D 2 254 ? 320.482 277.552 278.845 1.00 37.15  ? 252 ILE D O   1 
ATOM   11023 C  CB  . ILE D 2 254 ? 320.633 275.645 276.491 1.00 28.09  ? 252 ILE D CB  1 
ATOM   11024 C  CG1 . ILE D 2 254 ? 320.119 274.815 275.317 1.00 30.01  ? 252 ILE D CG1 1 
ATOM   11025 C  CG2 . ILE D 2 254 ? 321.941 275.066 277.005 1.00 25.63  ? 252 ILE D CG2 1 
ATOM   11026 C  CD1 . ILE D 2 254 ? 320.576 275.316 273.970 1.00 31.03  ? 252 ILE D CD1 1 
ATOM   11027 N  N   . VAL D 2 255 ? 320.219 275.607 279.946 1.00 29.34  ? 253 VAL D N   1 
ATOM   11028 C  CA  . VAL D 2 255 ? 320.805 276.104 281.180 1.00 29.82  ? 253 VAL D CA  1 
ATOM   11029 C  C   . VAL D 2 255 ? 322.184 275.522 281.440 1.00 28.88  ? 253 VAL D C   1 
ATOM   11030 O  O   . VAL D 2 255 ? 322.943 276.105 282.228 1.00 34.85  ? 253 VAL D O   1 
ATOM   11031 C  CB  . VAL D 2 255 ? 319.881 275.843 282.388 1.00 27.99  ? 253 VAL D CB  1 
ATOM   11032 C  CG1 . VAL D 2 255 ? 318.498 276.410 282.124 1.00 25.13  ? 253 VAL D CG1 1 
ATOM   11033 C  CG2 . VAL D 2 255 ? 319.810 274.358 282.689 1.00 28.81  ? 253 VAL D CG2 1 
ATOM   11034 N  N   . LYS D 2 256 ? 322.534 274.401 280.816 1.00 31.99  ? 254 LYS D N   1 
ATOM   11035 C  CA  . LYS D 2 256 ? 323.864 273.840 280.995 1.00 27.57  ? 254 LYS D CA  1 
ATOM   11036 C  C   . LYS D 2 256 ? 324.245 273.036 279.762 1.00 30.40  ? 254 LYS D C   1 
ATOM   11037 O  O   . LYS D 2 256 ? 323.390 272.608 278.986 1.00 29.17  ? 254 LYS D O   1 
ATOM   11038 C  CB  . LYS D 2 256 ? 323.940 272.968 282.252 1.00 29.43  ? 254 LYS D CB  1 
ATOM   11039 C  CG  . LYS D 2 256 ? 325.326 272.446 282.572 1.00 30.42  ? 254 LYS D CG  1 
ATOM   11040 C  CD  . LYS D 2 256 ? 325.348 271.763 283.925 1.00 32.08  ? 254 LYS D CD  1 
ATOM   11041 C  CE  . LYS D 2 256 ? 326.488 270.769 284.027 1.00 34.05  ? 254 LYS D CE  1 
ATOM   11042 N  NZ  . LYS D 2 256 ? 327.683 271.211 283.263 1.00 42.89  ? 254 LYS D NZ  1 
ATOM   11043 N  N   . THR D 2 257 ? 325.546 272.836 279.595 1.00 33.33  ? 255 THR D N   1 
ATOM   11044 C  CA  . THR D 2 257 ? 326.081 272.040 278.503 1.00 25.20  ? 255 THR D CA  1 
ATOM   11045 C  C   . THR D 2 257 ? 327.303 271.292 279.006 1.00 28.13  ? 255 THR D C   1 
ATOM   11046 O  O   . THR D 2 257 ? 328.097 271.839 279.775 1.00 35.39  ? 255 THR D O   1 
ATOM   11047 C  CB  . THR D 2 257 ? 326.449 272.914 277.297 1.00 27.82  ? 255 THR D CB  1 
ATOM   11048 O  OG1 . THR D 2 257 ? 325.490 272.722 276.250 1.00 30.34  ? 255 THR D OG1 1 
ATOM   11049 C  CG2 . THR D 2 257 ? 327.837 272.570 276.784 1.00 33.34  ? 255 THR D CG2 1 
ATOM   11050 N  N   . GLU D 2 258 ? 327.442 270.038 278.590 1.00 27.77  ? 256 GLU D N   1 
ATOM   11051 C  CA  . GLU D 2 258 ? 328.601 269.245 278.981 1.00 30.27  ? 256 GLU D CA  1 
ATOM   11052 C  C   . GLU D 2 258 ? 329.849 269.829 278.335 1.00 32.63  ? 256 GLU D C   1 
ATOM   11053 O  O   . GLU D 2 258 ? 330.053 269.695 277.124 1.00 39.56  ? 256 GLU D O   1 
ATOM   11054 C  CB  . GLU D 2 258 ? 328.406 267.787 278.582 1.00 29.80  ? 256 GLU D CB  1 
ATOM   11055 C  CG  . GLU D 2 258 ? 329.265 266.822 279.375 1.00 38.11  ? 256 GLU D CG  1 
ATOM   11056 C  CD  . GLU D 2 258 ? 329.451 265.493 278.679 1.00 46.87  ? 256 GLU D CD  1 
ATOM   11057 O  OE1 . GLU D 2 258 ? 330.402 265.368 277.881 1.00 58.46  ? 256 GLU D OE1 1 
ATOM   11058 O  OE2 . GLU D 2 258 ? 328.651 264.569 278.935 1.00 47.46  ? 256 GLU D OE2 1 
ATOM   11059 N  N   . ASN D 2 259 ? 330.685 270.481 279.137 1.00 33.54  ? 257 ASN D N   1 
ATOM   11060 C  CA  . ASN D 2 259 ? 331.920 271.085 278.663 1.00 34.01  ? 257 ASN D CA  1 
ATOM   11061 C  C   . ASN D 2 259 ? 333.073 270.583 279.522 1.00 31.27  ? 257 ASN D C   1 
ATOM   11062 O  O   . ASN D 2 259 ? 332.882 269.824 280.476 1.00 37.99  ? 257 ASN D O   1 
ATOM   11063 C  CB  . ASN D 2 259 ? 331.837 272.617 278.679 1.00 34.33  ? 257 ASN D CB  1 
ATOM   11064 C  CG  . ASN D 2 259 ? 331.476 273.171 280.040 1.00 33.12  ? 257 ASN D CG  1 
ATOM   11065 O  OD1 . ASN D 2 259 ? 332.344 273.397 280.880 1.00 37.47  ? 257 ASN D OD1 1 
ATOM   11066 N  ND2 . ASN D 2 259 ? 330.190 273.401 280.262 1.00 32.75  ? 257 ASN D ND2 1 
ATOM   11067 N  N   . LEU D 2 260 ? 334.285 271.011 279.174 1.00 29.56  ? 258 LEU D N   1 
ATOM   11068 C  CA  . LEU D 2 260 ? 335.482 270.526 279.847 1.00 34.50  ? 258 LEU D CA  1 
ATOM   11069 C  C   . LEU D 2 260 ? 335.725 271.193 281.194 1.00 37.91  ? 258 LEU D C   1 
ATOM   11070 O  O   . LEU D 2 260 ? 336.527 270.682 281.983 1.00 38.35  ? 258 LEU D O   1 
ATOM   11071 C  CB  . LEU D 2 260 ? 336.701 270.725 278.944 1.00 28.88  ? 258 LEU D CB  1 
ATOM   11072 C  CG  . LEU D 2 260 ? 336.671 269.950 277.625 1.00 23.90  ? 258 LEU D CG  1 
ATOM   11073 C  CD1 . LEU D 2 260 ? 337.787 270.405 276.703 1.00 16.98  ? 258 LEU D CD1 1 
ATOM   11074 C  CD2 . LEU D 2 260 ? 336.760 268.458 277.879 1.00 20.75  ? 258 LEU D CD2 1 
ATOM   11075 N  N   . HIS D 2 261 ? 335.063 272.310 281.477 1.00 36.52  ? 259 HIS D N   1 
ATOM   11076 C  CA  . HIS D 2 261 ? 335.199 272.988 282.758 1.00 39.90  ? 259 HIS D CA  1 
ATOM   11077 C  C   . HIS D 2 261 ? 334.041 272.709 283.704 1.00 44.32  ? 259 HIS D C   1 
ATOM   11078 O  O   . HIS D 2 261 ? 334.047 273.213 284.831 1.00 44.93  ? 259 HIS D O   1 
ATOM   11079 C  CB  . HIS D 2 261 ? 335.340 274.498 282.542 1.00 40.19  ? 259 HIS D CB  1 
ATOM   11080 C  CG  . HIS D 2 261 ? 336.637 274.897 281.913 1.00 48.47  ? 259 HIS D CG  1 
ATOM   11081 N  ND1 . HIS D 2 261 ? 336.721 275.391 280.630 1.00 56.87  ? 259 HIS D ND1 1 
ATOM   11082 C  CD2 . HIS D 2 261 ? 337.903 274.874 282.391 1.00 48.12  ? 259 HIS D CD2 1 
ATOM   11083 C  CE1 . HIS D 2 261 ? 337.983 275.657 280.345 1.00 54.31  ? 259 HIS D CE1 1 
ATOM   11084 N  NE2 . HIS D 2 261 ? 338.721 275.352 281.397 1.00 53.88  ? 259 HIS D NE2 1 
ATOM   11085 N  N   . ASN D 2 262 ? 333.057 271.915 283.282 1.00 41.94  ? 260 ASN D N   1 
ATOM   11086 C  CA  . ASN D 2 262 ? 331.891 271.606 284.107 1.00 41.04  ? 260 ASN D CA  1 
ATOM   11087 C  C   . ASN D 2 262 ? 331.123 272.868 284.485 1.00 42.29  ? 260 ASN D C   1 
ATOM   11088 O  O   . ASN D 2 262 ? 330.468 272.923 285.528 1.00 48.22  ? 260 ASN D O   1 
ATOM   11089 C  CB  . ASN D 2 262 ? 332.293 270.829 285.363 1.00 44.26  ? 260 ASN D CB  1 
ATOM   11090 C  CG  . ASN D 2 262 ? 331.204 269.891 285.841 1.00 47.46  ? 260 ASN D CG  1 
ATOM   11091 O  OD1 . ASN D 2 262 ? 330.276 269.572 285.101 1.00 51.33  ? 260 ASN D OD1 1 
ATOM   11092 N  ND2 . ASN D 2 262 ? 331.312 269.445 287.086 1.00 51.09  ? 260 ASN D ND2 1 
ATOM   11093 N  N   . ARG D 2 263 ? 331.198 273.889 283.639 1.00 44.04  ? 261 ARG D N   1 
ATOM   11094 C  CA  . ARG D 2 263 ? 330.543 275.157 283.912 1.00 44.39  ? 261 ARG D CA  1 
ATOM   11095 C  C   . ARG D 2 263 ? 329.073 275.114 283.516 1.00 44.06  ? 261 ARG D C   1 
ATOM   11096 O  O   . ARG D 2 263 ? 328.685 274.466 282.540 1.00 40.83  ? 261 ARG D O   1 
ATOM   11097 C  CB  . ARG D 2 263 ? 331.236 276.293 283.162 1.00 48.29  ? 261 ARG D CB  1 
ATOM   11098 C  CG  . ARG D 2 263 ? 332.550 276.736 283.773 1.00 55.74  ? 261 ARG D CG  1 
ATOM   11099 C  CD  . ARG D 2 263 ? 332.901 278.138 283.318 1.00 65.38  ? 261 ARG D CD  1 
ATOM   11100 N  NE  . ARG D 2 263 ? 332.467 278.391 281.950 1.00 67.20  ? 261 ARG D NE  1 
ATOM   11101 C  CZ  . ARG D 2 263 ? 332.819 279.453 281.239 1.00 69.34  ? 261 ARG D CZ  1 
ATOM   11102 N  NH1 . ARG D 2 263 ? 333.598 280.396 281.744 1.00 67.31  ? 261 ARG D NH1 1 
ATOM   11103 N  NH2 . ARG D 2 263 ? 332.371 279.577 279.993 1.00 62.16  ? 261 ARG D NH2 1 
ATOM   11104 N  N   . ALA D 2 264 ? 328.256 275.817 284.290 1.00 46.65  ? 262 ALA D N   1 
ATOM   11105 C  CA  . ALA D 2 264 ? 326.859 276.044 283.962 1.00 44.39  ? 262 ALA D CA  1 
ATOM   11106 C  C   . ALA D 2 264 ? 326.679 277.473 283.469 1.00 46.86  ? 262 ALA D C   1 
ATOM   11107 O  O   . ALA D 2 264 ? 327.438 278.374 283.832 1.00 51.49  ? 262 ALA D O   1 
ATOM   11108 C  CB  . ALA D 2 264 ? 325.960 275.788 285.172 1.00 41.10  ? 262 ALA D CB  1 
ATOM   11109 N  N   . LEU D 2 265 ? 325.660 277.675 282.631 1.00 44.47  ? 263 LEU D N   1 
ATOM   11110 C  CA  . LEU D 2 265 ? 325.428 279.000 282.067 1.00 43.95  ? 263 LEU D CA  1 
ATOM   11111 C  C   . LEU D 2 265 ? 325.275 280.057 283.152 1.00 50.23  ? 263 LEU D C   1 
ATOM   11112 O  O   . LEU D 2 265 ? 325.644 281.217 282.943 1.00 52.28  ? 263 LEU D O   1 
ATOM   11113 C  CB  . LEU D 2 265 ? 324.195 278.979 281.165 1.00 42.59  ? 263 LEU D CB  1 
ATOM   11114 C  CG  . LEU D 2 265 ? 324.467 278.955 279.661 1.00 38.89  ? 263 LEU D CG  1 
ATOM   11115 C  CD1 . LEU D 2 265 ? 325.078 277.628 279.243 1.00 36.41  ? 263 LEU D CD1 1 
ATOM   11116 C  CD2 . LEU D 2 265 ? 323.193 279.230 278.880 1.00 39.42  ? 263 LEU D CD2 1 
ATOM   11117 N  N   . ALA D 2 266 ? 324.739 279.680 284.315 1.00 56.34  ? 264 ALA D N   1 
ATOM   11118 C  CA  . ALA D 2 266 ? 324.544 280.651 285.386 1.00 55.31  ? 264 ALA D CA  1 
ATOM   11119 C  C   . ALA D 2 266 ? 325.867 281.187 285.912 1.00 56.58  ? 264 ALA D C   1 
ATOM   11120 O  O   . ALA D 2 266 ? 325.944 282.351 286.323 1.00 64.32  ? 264 ALA D O   1 
ATOM   11121 C  CB  . ALA D 2 266 ? 323.737 280.025 286.523 1.00 51.60  ? 264 ALA D CB  1 
ATOM   11122 N  N   . GLU D 2 267 ? 326.915 280.363 285.910 1.00 52.18  ? 265 GLU D N   1 
ATOM   11123 C  CA  . GLU D 2 267 ? 328.199 280.772 286.467 1.00 52.18  ? 265 GLU D CA  1 
ATOM   11124 C  C   . GLU D 2 267 ? 328.880 281.873 285.666 1.00 58.09  ? 265 GLU D C   1 
ATOM   11125 O  O   . GLU D 2 267 ? 329.819 282.490 286.180 1.00 62.44  ? 265 GLU D O   1 
ATOM   11126 C  CB  . GLU D 2 267 ? 329.130 279.564 286.575 1.00 52.21  ? 265 GLU D CB  1 
ATOM   11127 C  CG  . GLU D 2 267 ? 328.503 278.361 287.260 1.00 54.23  ? 265 GLU D CG  1 
ATOM   11128 C  CD  . GLU D 2 267 ? 329.409 277.147 287.253 1.00 58.95  ? 265 GLU D CD  1 
ATOM   11129 O  OE1 . GLU D 2 267 ? 330.645 277.325 287.280 1.00 62.33  ? 265 GLU D OE1 1 
ATOM   11130 O  OE2 . GLU D 2 267 ? 328.887 276.014 287.222 1.00 55.42  ? 265 GLU D OE2 1 
ATOM   11131 N  N   . TYR D 2 268 ? 328.443 282.138 284.431 1.00 63.15  ? 266 TYR D N   1 
ATOM   11132 C  CA  . TYR D 2 268 ? 329.050 283.203 283.642 1.00 61.72  ? 266 TYR D CA  1 
ATOM   11133 C  C   . TYR D 2 268 ? 328.030 284.060 282.899 1.00 62.04  ? 266 TYR D C   1 
ATOM   11134 O  O   . TYR D 2 268 ? 328.429 284.865 282.049 1.00 63.82  ? 266 TYR D O   1 
ATOM   11135 C  CB  . TYR D 2 268 ? 330.073 282.628 282.651 1.00 58.41  ? 266 TYR D CB  1 
ATOM   11136 C  CG  . TYR D 2 268 ? 329.512 281.626 281.669 1.00 60.36  ? 266 TYR D CG  1 
ATOM   11137 C  CD1 . TYR D 2 268 ? 329.395 280.285 282.007 1.00 57.81  ? 266 TYR D CD1 1 
ATOM   11138 C  CD2 . TYR D 2 268 ? 329.111 282.018 280.400 1.00 61.22  ? 266 TYR D CD2 1 
ATOM   11139 C  CE1 . TYR D 2 268 ? 328.889 279.366 281.113 1.00 54.93  ? 266 TYR D CE1 1 
ATOM   11140 C  CE2 . TYR D 2 268 ? 328.602 281.106 279.501 1.00 55.73  ? 266 TYR D CE2 1 
ATOM   11141 C  CZ  . TYR D 2 268 ? 328.493 279.782 279.861 1.00 56.32  ? 266 TYR D CZ  1 
ATOM   11142 O  OH  . TYR D 2 268 ? 327.988 278.871 278.964 1.00 52.55  ? 266 TYR D OH  1 
ATOM   11143 N  N   . CYS D 2 269 ? 326.735 283.919 283.186 1.00 61.10  ? 267 CYS D N   1 
ATOM   11144 C  CA  . CYS D 2 269 ? 325.689 284.778 282.628 1.00 68.38  ? 267 CYS D CA  1 
ATOM   11145 C  C   . CYS D 2 269 ? 324.895 285.367 283.786 1.00 71.70  ? 267 CYS D C   1 
ATOM   11146 O  O   . CYS D 2 269 ? 323.887 284.787 284.219 1.00 71.05  ? 267 CYS D O   1 
ATOM   11147 C  CB  . CYS D 2 269 ? 324.781 284.004 281.674 1.00 68.25  ? 267 CYS D CB  1 
ATOM   11148 S  SG  . CYS D 2 269 ? 325.644 283.027 280.424 1.00 64.34  ? 267 CYS D SG  1 
ATOM   11149 N  N   . PRO D 2 270 ? 325.309 286.519 284.320 1.00 75.94  ? 268 PRO D N   1 
ATOM   11150 C  CA  . PRO D 2 270 ? 324.637 287.070 285.505 1.00 70.67  ? 268 PRO D CA  1 
ATOM   11151 C  C   . PRO D 2 270 ? 323.175 287.417 285.269 1.00 69.27  ? 268 PRO D C   1 
ATOM   11152 O  O   . PRO D 2 270 ? 322.293 286.929 285.982 1.00 72.91  ? 268 PRO D O   1 
ATOM   11153 C  CB  . PRO D 2 270 ? 325.459 288.327 285.820 1.00 70.07  ? 268 PRO D CB  1 
ATOM   11154 C  CG  . PRO D 2 270 ? 326.778 288.101 285.154 1.00 69.64  ? 268 PRO D CG  1 
ATOM   11155 C  CD  . PRO D 2 270 ? 326.461 287.338 283.909 1.00 75.00  ? 268 PRO D CD  1 
ATOM   11156 N  N   . THR D 2 271 ? 322.908 288.262 284.278 1.00 69.98  ? 269 THR D N   1 
ATOM   11157 C  CA  . THR D 2 271 ? 321.548 288.709 284.026 1.00 72.58  ? 269 THR D CA  1 
ATOM   11158 C  C   . THR D 2 271 ? 320.761 287.659 283.243 1.00 71.21  ? 269 THR D C   1 
ATOM   11159 O  O   . THR D 2 271 ? 321.337 286.881 282.479 1.00 70.44  ? 269 THR D O   1 
ATOM   11160 C  CB  . THR D 2 271 ? 321.553 290.027 283.256 1.00 73.98  ? 269 THR D CB  1 
ATOM   11161 O  OG1 . THR D 2 271 ? 320.237 290.300 282.759 1.00 75.03  ? 269 THR D OG1 1 
ATOM   11162 C  CG2 . THR D 2 271 ? 322.531 289.967 282.093 1.00 72.76  ? 269 THR D CG2 1 
ATOM   11163 N  N   . PRO D 2 272 ? 319.439 287.616 283.424 1.00 69.04  ? 270 PRO D N   1 
ATOM   11164 C  CA  . PRO D 2 272 ? 318.625 286.677 282.634 1.00 68.32  ? 270 PRO D CA  1 
ATOM   11165 C  C   . PRO D 2 272 ? 318.716 286.911 281.137 1.00 69.67  ? 270 PRO D C   1 
ATOM   11166 O  O   . PRO D 2 272 ? 318.668 285.946 280.363 1.00 74.02  ? 270 PRO D O   1 
ATOM   11167 C  CB  . PRO D 2 272 ? 317.201 286.918 283.158 1.00 68.95  ? 270 PRO D CB  1 
ATOM   11168 C  CG  . PRO D 2 272 ? 317.249 288.254 283.830 1.00 69.03  ? 270 PRO D CG  1 
ATOM   11169 C  CD  . PRO D 2 272 ? 318.630 288.388 284.380 1.00 69.04  ? 270 PRO D CD  1 
ATOM   11170 N  N   . ASP D 2 273 ? 318.845 288.167 280.703 1.00 69.66  ? 271 ASP D N   1 
ATOM   11171 C  CA  . ASP D 2 273 ? 318.954 288.448 279.275 1.00 68.41  ? 271 ASP D CA  1 
ATOM   11172 C  C   . ASP D 2 273 ? 320.203 287.808 278.687 1.00 66.68  ? 271 ASP D C   1 
ATOM   11173 O  O   . ASP D 2 273 ? 320.168 287.247 277.584 1.00 65.72  ? 271 ASP D O   1 
ATOM   11174 C  CB  . ASP D 2 273 ? 318.960 289.957 279.041 1.00 69.98  ? 271 ASP D CB  1 
ATOM   11175 C  CG  . ASP D 2 273 ? 317.690 290.625 279.525 1.00 75.57  ? 271 ASP D CG  1 
ATOM   11176 O  OD1 . ASP D 2 273 ? 316.653 289.934 279.623 1.00 78.62  ? 271 ASP D OD1 1 
ATOM   11177 O  OD2 . ASP D 2 273 ? 317.729 291.838 279.817 1.00 78.06  ? 271 ASP D OD2 1 
ATOM   11178 N  N   . SER D 2 274 ? 321.321 287.881 279.412 1.00 64.76  ? 272 SER D N   1 
ATOM   11179 C  CA  . SER D 2 274 ? 322.536 287.215 278.960 1.00 65.62  ? 272 SER D CA  1 
ATOM   11180 C  C   . SER D 2 274 ? 322.347 285.706 278.907 1.00 65.05  ? 272 SER D C   1 
ATOM   11181 O  O   . SER D 2 274 ? 322.882 285.037 278.016 1.00 64.88  ? 272 SER D O   1 
ATOM   11182 C  CB  . SER D 2 274 ? 323.703 287.582 279.873 1.00 70.74  ? 272 SER D CB  1 
ATOM   11183 O  OG  . SER D 2 274 ? 324.406 288.700 279.364 1.00 76.21  ? 272 SER D OG  1 
ATOM   11184 N  N   . MET D 2 275 ? 321.594 285.148 279.857 1.00 63.91  ? 273 MET D N   1 
ATOM   11185 C  CA  . MET D 2 275 ? 321.322 283.715 279.825 1.00 58.65  ? 273 MET D CA  1 
ATOM   11186 C  C   . MET D 2 275 ? 320.536 283.335 278.576 1.00 55.93  ? 273 MET D C   1 
ATOM   11187 O  O   . MET D 2 275 ? 320.850 282.337 277.915 1.00 56.51  ? 273 MET D O   1 
ATOM   11188 C  CB  . MET D 2 275 ? 320.569 283.295 281.086 1.00 54.89  ? 273 MET D CB  1 
ATOM   11189 C  CG  . MET D 2 275 ? 321.464 283.058 282.290 1.00 59.91  ? 273 MET D CG  1 
ATOM   11190 S  SD  . MET D 2 275 ? 320.847 281.769 283.387 1.00 74.80  ? 273 MET D SD  1 
ATOM   11191 C  CE  . MET D 2 275 ? 321.128 280.308 282.393 1.00 50.77  ? 273 MET D CE  1 
ATOM   11192 N  N   . LYS D 2 276 ? 319.517 284.126 278.231 1.00 56.77  ? 274 LYS D N   1 
ATOM   11193 C  CA  . LYS D 2 276 ? 318.764 283.854 277.011 1.00 56.34  ? 274 LYS D CA  1 
ATOM   11194 C  C   . LYS D 2 276 ? 319.650 283.982 275.778 1.00 56.81  ? 274 LYS D C   1 
ATOM   11195 O  O   . LYS D 2 276 ? 319.552 283.175 274.845 1.00 56.70  ? 274 LYS D O   1 
ATOM   11196 C  CB  . LYS D 2 276 ? 317.563 284.794 276.906 1.00 59.00  ? 274 LYS D CB  1 
ATOM   11197 C  CG  . LYS D 2 276 ? 316.972 285.206 278.242 1.00 67.45  ? 274 LYS D CG  1 
ATOM   11198 C  CD  . LYS D 2 276 ? 315.455 285.122 278.229 1.00 73.29  ? 274 LYS D CD  1 
ATOM   11199 C  CE  . LYS D 2 276 ? 314.888 285.159 279.640 1.00 71.81  ? 274 LYS D CE  1 
ATOM   11200 N  NZ  . LYS D 2 276 ? 314.134 283.919 279.966 1.00 64.80  ? 274 LYS D NZ  1 
ATOM   11201 N  N   . MET D 2 277 ? 320.524 284.990 275.757 1.00 58.62  ? 275 MET D N   1 
ATOM   11202 C  CA  . MET D 2 277 ? 321.426 285.158 274.623 1.00 55.14  ? 275 MET D CA  1 
ATOM   11203 C  C   . MET D 2 277 ? 322.353 283.957 274.473 1.00 52.09  ? 275 MET D C   1 
ATOM   11204 O  O   . MET D 2 277 ? 322.575 283.466 273.359 1.00 55.20  ? 275 MET D O   1 
ATOM   11205 C  CB  . MET D 2 277 ? 322.238 286.443 274.787 1.00 60.49  ? 275 MET D CB  1 
ATOM   11206 C  CG  . MET D 2 277 ? 321.445 287.718 274.558 1.00 66.34  ? 275 MET D CG  1 
ATOM   11207 S  SD  . MET D 2 277 ? 320.995 287.975 272.832 1.00 85.97  ? 275 MET D SD  1 
ATOM   11208 C  CE  . MET D 2 277 ? 319.367 287.232 272.789 1.00 63.76  ? 275 MET D CE  1 
ATOM   11209 N  N   . GLU D 2 278 ? 322.908 283.473 275.586 1.00 50.04  ? 276 GLU D N   1 
ATOM   11210 C  CA  . GLU D 2 278 ? 323.802 282.321 275.534 1.00 49.10  ? 276 GLU D CA  1 
ATOM   11211 C  C   . GLU D 2 278 ? 323.062 281.068 275.081 1.00 49.00  ? 276 GLU D C   1 
ATOM   11212 O  O   . GLU D 2 278 ? 323.599 280.260 274.310 1.00 50.14  ? 276 GLU D O   1 
ATOM   11213 C  CB  . GLU D 2 278 ? 324.450 282.102 276.900 1.00 45.23  ? 276 GLU D CB  1 
ATOM   11214 C  CG  . GLU D 2 278 ? 325.451 280.963 276.942 1.00 47.03  ? 276 GLU D CG  1 
ATOM   11215 C  CD  . GLU D 2 278 ? 326.637 281.187 276.023 1.00 56.07  ? 276 GLU D CD  1 
ATOM   11216 O  OE1 . GLU D 2 278 ? 326.598 282.135 275.211 1.00 56.08  ? 276 GLU D OE1 1 
ATOM   11217 O  OE2 . GLU D 2 278 ? 327.613 280.413 276.114 1.00 56.45  ? 276 GLU D OE2 1 
ATOM   11218 N  N   . SER D 2 279 ? 321.831 280.881 275.562 1.00 44.10  ? 277 SER D N   1 
ATOM   11219 C  CA  . SER D 2 279 ? 321.033 279.748 275.109 1.00 37.63  ? 277 SER D CA  1 
ATOM   11220 C  C   . SER D 2 279 ? 320.786 279.821 273.607 1.00 41.28  ? 277 SER D C   1 
ATOM   11221 O  O   . SER D 2 279 ? 320.881 278.808 272.901 1.00 43.38  ? 277 SER D O   1 
ATOM   11222 C  CB  . SER D 2 279 ? 319.711 279.705 275.874 1.00 35.91  ? 277 SER D CB  1 
ATOM   11223 O  OG  . SER D 2 279 ? 318.932 278.589 275.489 1.00 38.13  ? 277 SER D OG  1 
ATOM   11224 N  N   . LYS D 2 280 ? 320.470 281.015 273.101 1.00 41.59  ? 278 LYS D N   1 
ATOM   11225 C  CA  . LYS D 2 280 ? 320.281 281.185 271.664 1.00 43.34  ? 278 LYS D CA  1 
ATOM   11226 C  C   . LYS D 2 280 ? 321.558 280.856 270.901 1.00 43.85  ? 278 LYS D C   1 
ATOM   11227 O  O   . LYS D 2 280 ? 321.514 280.218 269.843 1.00 42.35  ? 278 LYS D O   1 
ATOM   11228 C  CB  . LYS D 2 280 ? 319.824 282.613 271.367 1.00 44.99  ? 278 LYS D CB  1 
ATOM   11229 C  CG  . LYS D 2 280 ? 318.925 282.742 270.153 1.00 51.68  ? 278 LYS D CG  1 
ATOM   11230 C  CD  . LYS D 2 280 ? 318.309 284.130 270.064 1.00 59.39  ? 278 LYS D CD  1 
ATOM   11231 C  CE  . LYS D 2 280 ? 317.924 284.656 271.439 1.00 59.93  ? 278 LYS D CE  1 
ATOM   11232 N  NZ  . LYS D 2 280 ? 316.692 284.002 271.961 1.00 51.15  ? 278 LYS D NZ  1 
ATOM   11233 N  N   . ARG D 2 281 ? 322.706 281.282 271.428 1.00 43.24  ? 279 ARG D N   1 
ATOM   11234 C  CA  . ARG D 2 281 ? 323.983 280.990 270.783 1.00 39.91  ? 279 ARG D CA  1 
ATOM   11235 C  C   . ARG D 2 281 ? 324.243 279.488 270.708 1.00 40.76  ? 279 ARG D C   1 
ATOM   11236 O  O   . ARG D 2 281 ? 324.671 278.971 269.668 1.00 41.28  ? 279 ARG D O   1 
ATOM   11237 C  CB  . ARG D 2 281 ? 325.104 281.703 271.540 1.00 40.96  ? 279 ARG D CB  1 
ATOM   11238 C  CG  . ARG D 2 281 ? 326.362 281.955 270.739 1.00 43.56  ? 279 ARG D CG  1 
ATOM   11239 C  CD  . ARG D 2 281 ? 327.566 282.019 271.659 1.00 43.59  ? 279 ARG D CD  1 
ATOM   11240 N  NE  . ARG D 2 281 ? 327.558 280.937 272.635 1.00 45.53  ? 279 ARG D NE  1 
ATOM   11241 C  CZ  . ARG D 2 281 ? 328.527 280.042 272.769 1.00 46.88  ? 279 ARG D CZ  1 
ATOM   11242 N  NH1 . ARG D 2 281 ? 329.608 280.076 272.009 1.00 53.83  ? 279 ARG D NH1 1 
ATOM   11243 N  NH2 . ARG D 2 281 ? 328.409 279.092 273.691 1.00 47.07  ? 279 ARG D NH2 1 
ATOM   11244 N  N   . ILE D 2 282 ? 323.986 278.767 271.800 1.00 40.35  ? 280 ILE D N   1 
ATOM   11245 C  CA  . ILE D 2 282 ? 324.234 277.326 271.804 1.00 36.88  ? 280 ILE D CA  1 
ATOM   11246 C  C   . ILE D 2 282 ? 323.266 276.608 270.865 1.00 36.39  ? 280 ILE D C   1 
ATOM   11247 O  O   . ILE D 2 282 ? 323.643 275.656 270.162 1.00 40.45  ? 280 ILE D O   1 
ATOM   11248 C  CB  . ILE D 2 282 ? 324.155 276.779 273.241 1.00 36.86  ? 280 ILE D CB  1 
ATOM   11249 C  CG1 . ILE D 2 282 ? 325.295 277.354 274.084 1.00 37.64  ? 280 ILE D CG1 1 
ATOM   11250 C  CG2 . ILE D 2 282 ? 324.218 275.264 273.238 1.00 33.17  ? 280 ILE D CG2 1 
ATOM   11251 C  CD1 . ILE D 2 282 ? 325.062 277.270 275.571 1.00 33.02  ? 280 ILE D CD1 1 
ATOM   11252 N  N   . ASP D 2 283 ? 322.004 277.044 270.840 1.00 33.91  ? 281 ASP D N   1 
ATOM   11253 C  CA  . ASP D 2 283 ? 321.049 276.455 269.908 1.00 33.66  ? 281 ASP D CA  1 
ATOM   11254 C  C   . ASP D 2 283 ? 321.473 276.705 268.468 1.00 37.06  ? 281 ASP D C   1 
ATOM   11255 O  O   . ASP D 2 283 ? 321.313 275.835 267.601 1.00 39.10  ? 281 ASP D O   1 
ATOM   11256 C  CB  . ASP D 2 283 ? 319.651 277.014 270.169 1.00 37.72  ? 281 ASP D CB  1 
ATOM   11257 C  CG  . ASP D 2 283 ? 318.815 276.104 271.045 1.00 46.46  ? 281 ASP D CG  1 
ATOM   11258 O  OD1 . ASP D 2 283 ? 318.747 274.892 270.755 1.00 46.09  ? 281 ASP D OD1 1 
ATOM   11259 O  OD2 . ASP D 2 283 ? 318.230 276.601 272.030 1.00 50.42  ? 281 ASP D OD2 1 
ATOM   11260 N  N   . LYS D 2 284 ? 322.022 277.891 268.195 1.00 40.55  ? 282 LYS D N   1 
ATOM   11261 C  CA  . LYS D 2 284 ? 322.569 278.167 266.873 1.00 36.03  ? 282 LYS D CA  1 
ATOM   11262 C  C   . LYS D 2 284 ? 323.731 277.239 266.556 1.00 36.00  ? 282 LYS D C   1 
ATOM   11263 O  O   . LYS D 2 284 ? 323.875 276.791 265.418 1.00 42.00  ? 282 LYS D O   1 
ATOM   11264 C  CB  . LYS D 2 284 ? 323.009 279.626 266.774 1.00 38.92  ? 282 LYS D CB  1 
ATOM   11265 C  CG  . LYS D 2 284 ? 321.953 280.551 266.205 1.00 43.40  ? 282 LYS D CG  1 
ATOM   11266 C  CD  . LYS D 2 284 ? 322.590 281.796 265.618 1.00 53.26  ? 282 LYS D CD  1 
ATOM   11267 C  CE  . LYS D 2 284 ? 323.773 281.435 264.735 1.00 61.05  ? 282 LYS D CE  1 
ATOM   11268 N  NZ  . LYS D 2 284 ? 323.350 281.098 263.349 1.00 60.57  ? 282 LYS D NZ  1 
ATOM   11269 N  N   . GLU D 2 285 ? 324.579 276.950 267.543 1.00 33.29  ? 283 GLU D N   1 
ATOM   11270 C  CA  . GLU D 2 285 ? 325.677 276.012 267.315 1.00 31.84  ? 283 GLU D CA  1 
ATOM   11271 C  C   . GLU D 2 285 ? 325.152 274.643 266.896 1.00 34.41  ? 283 GLU D C   1 
ATOM   11272 O  O   . GLU D 2 285 ? 325.651 274.032 265.941 1.00 34.96  ? 283 GLU D O   1 
ATOM   11273 C  CB  . GLU D 2 285 ? 326.533 275.883 268.573 1.00 33.56  ? 283 GLU D CB  1 
ATOM   11274 C  CG  . GLU D 2 285 ? 327.635 276.907 268.695 1.00 39.67  ? 283 GLU D CG  1 
ATOM   11275 C  CD  . GLU D 2 285 ? 328.175 276.995 270.106 1.00 51.81  ? 283 GLU D CD  1 
ATOM   11276 O  OE1 . GLU D 2 285 ? 328.388 278.123 270.592 1.00 56.91  ? 283 GLU D OE1 1 
ATOM   11277 O  OE2 . GLU D 2 285 ? 328.380 275.934 270.733 1.00 46.76  ? 283 GLU D OE2 1 
ATOM   11278 N  N   . LEU D 2 286 ? 324.148 274.138 267.614 1.00 31.99  ? 284 LEU D N   1 
ATOM   11279 C  CA  . LEU D 2 286 ? 323.601 272.821 267.286 1.00 26.92  ? 284 LEU D CA  1 
ATOM   11280 C  C   . LEU D 2 286 ? 322.969 272.817 265.896 1.00 33.27  ? 284 LEU D C   1 
ATOM   11281 O  O   . LEU D 2 286 ? 323.216 271.913 265.079 1.00 34.39  ? 284 LEU D O   1 
ATOM   11282 C  CB  . LEU D 2 286 ? 322.583 272.402 268.344 1.00 27.31  ? 284 LEU D CB  1 
ATOM   11283 C  CG  . LEU D 2 286 ? 323.133 272.134 269.745 1.00 28.67  ? 284 LEU D CG  1 
ATOM   11284 C  CD1 . LEU D 2 286 ? 322.006 272.091 270.761 1.00 29.62  ? 284 LEU D CD1 1 
ATOM   11285 C  CD2 . LEU D 2 286 ? 323.931 270.843 269.774 1.00 24.51  ? 284 LEU D CD2 1 
ATOM   11286 N  N   . GLN D 2 287 ? 322.148 273.829 265.608 1.00 35.14  ? 285 GLN D N   1 
ATOM   11287 C  CA  . GLN D 2 287 ? 321.511 273.904 264.299 1.00 35.29  ? 285 GLN D CA  1 
ATOM   11288 C  C   . GLN D 2 287 ? 322.548 274.055 263.196 1.00 34.71  ? 285 GLN D C   1 
ATOM   11289 O  O   . GLN D 2 287 ? 322.371 273.533 262.091 1.00 36.18  ? 285 GLN D O   1 
ATOM   11290 C  CB  . GLN D 2 287 ? 320.510 275.058 264.269 1.00 36.09  ? 285 GLN D CB  1 
ATOM   11291 C  CG  . GLN D 2 287 ? 319.805 275.231 262.937 1.00 41.39  ? 285 GLN D CG  1 
ATOM   11292 C  CD  . GLN D 2 287 ? 319.009 274.006 262.536 1.00 50.16  ? 285 GLN D CD  1 
ATOM   11293 O  OE1 . GLN D 2 287 ? 318.326 273.397 263.359 1.00 46.46  ? 285 GLN D OE1 1 
ATOM   11294 N  NE2 . GLN D 2 287 ? 319.092 273.638 261.263 1.00 49.19  ? 285 GLN D NE2 1 
ATOM   11295 N  N   . GLY D 2 288 ? 323.641 274.765 263.478 1.00 33.14  ? 286 GLY D N   1 
ATOM   11296 C  CA  . GLY D 2 288 ? 324.696 274.913 262.494 1.00 31.24  ? 286 GLY D CA  1 
ATOM   11297 C  C   . GLY D 2 288 ? 325.422 273.614 262.222 1.00 30.79  ? 286 GLY D C   1 
ATOM   11298 O  O   . GLY D 2 288 ? 325.796 273.334 261.083 1.00 36.21  ? 286 GLY D O   1 
ATOM   11299 N  N   . PHE D 2 289 ? 325.645 272.806 263.260 1.00 30.19  ? 287 PHE D N   1 
ATOM   11300 C  CA  . PHE D 2 289 ? 326.197 271.475 263.023 1.00 28.02  ? 287 PHE D CA  1 
ATOM   11301 C  C   . PHE D 2 289 ? 325.284 270.670 262.104 1.00 27.94  ? 287 PHE D C   1 
ATOM   11302 O  O   . PHE D 2 289 ? 325.735 270.086 261.104 1.00 27.94  ? 287 PHE D O   1 
ATOM   11303 C  CB  . PHE D 2 289 ? 326.412 270.735 264.344 1.00 20.40  ? 287 PHE D CB  1 
ATOM   11304 C  CG  . PHE D 2 289 ? 326.776 269.291 264.163 1.00 17.28  ? 287 PHE D CG  1 
ATOM   11305 C  CD1 . PHE D 2 289 ? 328.063 268.927 263.806 1.00 15.13  ? 287 PHE D CD1 1 
ATOM   11306 C  CD2 . PHE D 2 289 ? 325.825 268.300 264.324 1.00 16.95  ? 287 PHE D CD2 1 
ATOM   11307 C  CE1 . PHE D 2 289 ? 328.395 267.603 263.622 1.00 13.27  ? 287 PHE D CE1 1 
ATOM   11308 C  CE2 . PHE D 2 289 ? 326.152 266.974 264.141 1.00 15.85  ? 287 PHE D CE2 1 
ATOM   11309 C  CZ  . PHE D 2 289 ? 327.439 266.624 263.790 1.00 14.29  ? 287 PHE D CZ  1 
ATOM   11310 N  N   . ARG D 2 290 ? 323.985 270.650 262.415 1.00 29.70  ? 288 ARG D N   1 
ATOM   11311 C  CA  . ARG D 2 290 ? 323.054 269.904 261.570 1.00 29.72  ? 288 ARG D CA  1 
ATOM   11312 C  C   . ARG D 2 290 ? 323.085 270.413 260.133 1.00 32.38  ? 288 ARG D C   1 
ATOM   11313 O  O   . ARG D 2 290 ? 323.103 269.623 259.183 1.00 36.26  ? 288 ARG D O   1 
ATOM   11314 C  CB  . ARG D 2 290 ? 321.633 269.979 262.127 1.00 34.56  ? 288 ARG D CB  1 
ATOM   11315 C  CG  . ARG D 2 290 ? 321.512 269.751 263.615 1.00 38.81  ? 288 ARG D CG  1 
ATOM   11316 C  CD  . ARG D 2 290 ? 320.050 269.631 264.000 1.00 41.98  ? 288 ARG D CD  1 
ATOM   11317 N  NE  . ARG D 2 290 ? 319.349 268.686 263.139 1.00 45.20  ? 288 ARG D NE  1 
ATOM   11318 C  CZ  . ARG D 2 290 ? 318.427 267.829 263.558 1.00 46.30  ? 288 ARG D CZ  1 
ATOM   11319 N  NH1 . ARG D 2 290 ? 318.067 267.769 264.829 1.00 43.17  ? 288 ARG D NH1 1 
ATOM   11320 N  NH2 . ARG D 2 290 ? 317.857 267.010 262.680 1.00 44.85  ? 288 ARG D NH2 1 
ATOM   11321 N  N   . ASP D 2 291 ? 323.080 271.735 259.954 1.00 30.83  ? 289 ASP D N   1 
ATOM   11322 C  CA  . ASP D 2 291 ? 323.073 272.299 258.608 1.00 30.21  ? 289 ASP D CA  1 
ATOM   11323 C  C   . ASP D 2 291 ? 324.362 271.977 257.863 1.00 30.97  ? 289 ASP D C   1 
ATOM   11324 O  O   . ASP D 2 291 ? 324.333 271.648 256.672 1.00 36.68  ? 289 ASP D O   1 
ATOM   11325 C  CB  . ASP D 2 291 ? 322.852 273.809 258.672 1.00 35.47  ? 289 ASP D CB  1 
ATOM   11326 C  CG  . ASP D 2 291 ? 321.445 274.176 259.100 1.00 46.34  ? 289 ASP D CG  1 
ATOM   11327 O  OD1 . ASP D 2 291 ? 320.524 273.357 258.894 1.00 42.86  ? 289 ASP D OD1 1 
ATOM   11328 O  OD2 . ASP D 2 291 ? 321.258 275.288 259.637 1.00 49.15  ? 289 ASP D OD2 1 
ATOM   11329 N  N   . GLY D 2 292 ? 325.504 272.070 258.544 1.00 29.86  ? 290 GLY D N   1 
ATOM   11330 C  CA  . GLY D 2 292 ? 326.779 271.803 257.911 1.00 30.14  ? 290 GLY D CA  1 
ATOM   11331 C  C   . GLY D 2 292 ? 326.996 270.350 257.568 1.00 29.73  ? 290 GLY D C   1 
ATOM   11332 O  O   . GLY D 2 292 ? 327.877 270.041 256.759 1.00 35.58  ? 290 GLY D O   1 
ATOM   11333 N  N   . LEU D 2 293 ? 326.221 269.446 258.171 1.00 28.22  ? 291 LEU D N   1 
ATOM   11334 C  CA  . LEU D 2 293 ? 326.309 268.045 257.770 1.00 24.66  ? 291 LEU D CA  1 
ATOM   11335 C  C   . LEU D 2 293 ? 326.121 267.870 256.265 1.00 23.20  ? 291 LEU D C   1 
ATOM   11336 O  O   . LEU D 2 293 ? 326.807 267.056 255.637 1.00 22.02  ? 291 LEU D O   1 
ATOM   11337 C  CB  . LEU D 2 293 ? 325.276 267.212 258.525 1.00 19.18  ? 291 LEU D CB  1 
ATOM   11338 C  CG  . LEU D 2 293 ? 325.620 266.825 259.961 1.00 21.75  ? 291 LEU D CG  1 
ATOM   11339 C  CD1 . LEU D 2 293 ? 324.429 266.152 260.614 1.00 20.97  ? 291 LEU D CD1 1 
ATOM   11340 C  CD2 . LEU D 2 293 ? 326.843 265.927 259.996 1.00 16.99  ? 291 LEU D CD2 1 
ATOM   11341 N  N   . PHE D 2 294 ? 325.204 268.625 255.666 1.00 26.50  ? 292 PHE D N   1 
ATOM   11342 C  CA  . PHE D 2 294 ? 324.761 268.366 254.305 1.00 28.84  ? 292 PHE D CA  1 
ATOM   11343 C  C   . PHE D 2 294 ? 325.095 269.529 253.382 1.00 30.13  ? 292 PHE D C   1 
ATOM   11344 O  O   . PHE D 2 294 ? 325.292 270.667 253.817 1.00 34.46  ? 292 PHE D O   1 
ATOM   11345 C  CB  . PHE D 2 294 ? 323.259 268.077 254.273 1.00 20.30  ? 292 PHE D CB  1 
ATOM   11346 C  CG  . PHE D 2 294 ? 322.868 266.905 255.113 1.00 18.86  ? 292 PHE D CG  1 
ATOM   11347 C  CD1 . PHE D 2 294 ? 323.216 265.620 254.737 1.00 17.30  ? 292 PHE D CD1 1 
ATOM   11348 C  CD2 . PHE D 2 294 ? 322.196 267.090 256.305 1.00 16.14  ? 292 PHE D CD2 1 
ATOM   11349 C  CE1 . PHE D 2 294 ? 322.872 264.542 255.519 1.00 15.32  ? 292 PHE D CE1 1 
ATOM   11350 C  CE2 . PHE D 2 294 ? 321.851 266.016 257.092 1.00 17.16  ? 292 PHE D CE2 1 
ATOM   11351 C  CZ  . PHE D 2 294 ? 322.188 264.740 256.698 1.00 17.46  ? 292 PHE D CZ  1 
ATOM   11352 N  N   . VAL D 2 295 ? 325.158 269.220 252.088 1.00 35.49  ? 293 VAL D N   1 
ATOM   11353 C  CA  . VAL D 2 295 ? 325.629 270.163 251.081 1.00 42.09  ? 293 VAL D CA  1 
ATOM   11354 C  C   . VAL D 2 295 ? 324.639 270.246 249.926 1.00 42.84  ? 293 VAL D C   1 
ATOM   11355 O  O   . VAL D 2 295 ? 324.971 270.755 248.850 1.00 48.37  ? 293 VAL D O   1 
ATOM   11356 C  CB  . VAL D 2 295 ? 327.025 269.763 250.571 1.00 40.69  ? 293 VAL D CB  1 
ATOM   11357 C  CG1 . VAL D 2 295 ? 327.911 269.327 251.730 1.00 31.56  ? 293 VAL D CG1 1 
ATOM   11358 C  CG2 . VAL D 2 295 ? 326.912 268.657 249.532 1.00 28.90  ? 293 VAL D CG2 1 
ATOM   11359 N  N   . THR D 2 296 ? 323.420 269.752 250.133 1.00 45.18  ? 294 THR D N   1 
ATOM   11360 C  CA  . THR D 2 296 ? 322.459 269.686 249.040 1.00 51.36  ? 294 THR D CA  1 
ATOM   11361 C  C   . THR D 2 296 ? 321.800 271.026 248.737 1.00 58.70  ? 294 THR D C   1 
ATOM   11362 O  O   . THR D 2 296 ? 321.111 271.139 247.719 1.00 62.52  ? 294 THR D O   1 
ATOM   11363 C  CB  . THR D 2 296 ? 321.379 268.645 249.342 1.00 47.63  ? 294 THR D CB  1 
ATOM   11364 O  OG1 . THR D 2 296 ? 320.857 268.127 248.112 1.00 39.79  ? 294 THR D OG1 1 
ATOM   11365 C  CG2 . THR D 2 296 ? 320.246 269.267 250.139 1.00 50.72  ? 294 THR D CG2 1 
ATOM   11366 N  N   . GLN D 2 297 ? 321.998 272.040 249.579 1.00 61.12  ? 295 GLN D N   1 
ATOM   11367 C  CA  . GLN D 2 297 ? 321.428 273.362 249.349 1.00 64.32  ? 295 GLN D CA  1 
ATOM   11368 C  C   . GLN D 2 297 ? 322.493 274.404 249.027 1.00 65.11  ? 295 GLN D C   1 
ATOM   11369 O  O   . GLN D 2 297 ? 322.225 275.606 249.108 1.00 71.35  ? 295 GLN D O   1 
ATOM   11370 C  CB  . GLN D 2 297 ? 320.598 273.801 250.555 1.00 61.91  ? 295 GLN D CB  1 
ATOM   11371 C  CG  . GLN D 2 297 ? 319.225 273.152 250.612 1.00 69.82  ? 295 GLN D CG  1 
ATOM   11372 C  CD  . GLN D 2 297 ? 318.746 272.909 252.026 1.00 75.20  ? 295 GLN D CD  1 
ATOM   11373 O  OE1 . GLN D 2 297 ? 318.964 273.729 252.917 1.00 80.38  ? 295 GLN D OE1 1 
ATOM   11374 N  NE2 . GLN D 2 297 ? 318.090 271.775 252.241 1.00 76.04  ? 295 GLN D NE2 1 
ATOM   11375 N  N   . ASP D 2 298 ? 323.696 273.968 248.663 1.00 65.78  ? 296 ASP D N   1 
ATOM   11376 C  CA  . ASP D 2 298 ? 324.759 274.871 248.237 1.00 70.49  ? 296 ASP D CA  1 
ATOM   11377 C  C   . ASP D 2 298 ? 324.685 275.016 246.722 1.00 82.31  ? 296 ASP D C   1 
ATOM   11378 O  O   . ASP D 2 298 ? 324.843 274.035 245.989 1.00 81.97  ? 296 ASP D O   1 
ATOM   11379 C  CB  . ASP D 2 298 ? 326.128 274.352 248.673 1.00 67.88  ? 296 ASP D CB  1 
ATOM   11380 C  CG  . ASP D 2 298 ? 326.193 274.032 250.156 1.00 66.23  ? 296 ASP D CG  1 
ATOM   11381 O  OD1 . ASP D 2 298 ? 325.142 274.062 250.830 1.00 64.92  ? 296 ASP D OD1 1 
ATOM   11382 O  OD2 . ASP D 2 298 ? 327.304 273.747 250.651 1.00 61.79  ? 296 ASP D OD2 1 
ATOM   11383 N  N   . THR D 2 299 ? 324.442 276.240 246.251 1.00 90.88  ? 297 THR D N   1 
ATOM   11384 C  CA  . THR D 2 299 ? 324.329 276.521 244.825 1.00 93.20  ? 297 THR D CA  1 
ATOM   11385 C  C   . THR D 2 299 ? 325.518 277.319 244.298 1.00 92.57  ? 297 THR D C   1 
ATOM   11386 O  O   . THR D 2 299 ? 325.387 278.035 243.301 1.00 92.72  ? 297 THR D O   1 
ATOM   11387 C  CB  . THR D 2 299 ? 323.020 277.254 244.528 1.00 97.20  ? 297 THR D CB  1 
ATOM   11388 O  OG1 . THR D 2 299 ? 322.871 277.418 243.112 1.00 98.07  ? 297 THR D OG1 1 
ATOM   11389 C  CG2 . THR D 2 299 ? 323.011 278.618 245.191 1.00 102.39 ? 297 THR D CG2 1 
ATOM   11390 N  N   . THR D 2 300 ? 326.678 277.202 244.944 1.00 90.29  ? 298 THR D N   1 
ATOM   11391 C  CA  . THR D 2 300 ? 327.886 277.896 244.519 1.00 91.58  ? 298 THR D CA  1 
ATOM   11392 C  C   . THR D 2 300 ? 328.673 277.114 243.474 1.00 92.16  ? 298 THR D C   1 
ATOM   11393 O  O   . THR D 2 300 ? 329.873 277.353 243.298 1.00 90.98  ? 298 THR D O   1 
ATOM   11394 C  CB  . THR D 2 300 ? 328.776 278.193 245.729 1.00 94.83  ? 298 THR D CB  1 
ATOM   11395 O  OG1 . THR D 2 300 ? 329.966 278.866 245.301 1.00 98.45  ? 298 THR D OG1 1 
ATOM   11396 C  CG2 . THR D 2 300 ? 329.157 276.904 246.440 1.00 87.44  ? 298 THR D CG2 1 
ATOM   11397 N  N   . TRP D 2 301 ? 328.019 276.190 242.778 1.00 88.49  ? 299 TRP D N   1 
ATOM   11398 C  CA  . TRP D 2 301 ? 328.665 275.387 241.750 1.00 82.84  ? 299 TRP D CA  1 
ATOM   11399 C  C   . TRP D 2 301 ? 328.428 275.977 240.364 1.00 80.66  ? 299 TRP D C   1 
ATOM   11400 O  O   . TRP D 2 301 ? 327.584 276.856 240.189 1.00 78.49  ? 299 TRP D O   1 
ATOM   11401 C  CB  . TRP D 2 301 ? 328.156 273.946 241.805 1.00 78.96  ? 299 TRP D CB  1 
ATOM   11402 C  CG  . TRP D 2 301 ? 326.678 273.847 242.044 1.00 77.53  ? 299 TRP D CG  1 
ATOM   11403 C  CD1 . TRP D 2 301 ? 326.050 273.793 243.250 1.00 75.96  ? 299 TRP D CD1 1 
ATOM   11404 C  CD2 . TRP D 2 301 ? 325.646 273.801 241.051 1.00 74.50  ? 299 TRP D CD2 1 
ATOM   11405 N  NE1 . TRP D 2 301 ? 324.691 273.710 243.074 1.00 72.34  ? 299 TRP D NE1 1 
ATOM   11406 C  CE2 . TRP D 2 301 ? 324.417 273.714 241.732 1.00 70.95  ? 299 TRP D CE2 1 
ATOM   11407 C  CE3 . TRP D 2 301 ? 325.642 273.822 239.653 1.00 71.54  ? 299 TRP D CE3 1 
ATOM   11408 C  CZ2 . TRP D 2 301 ? 323.196 273.648 241.065 1.00 68.29  ? 299 TRP D CZ2 1 
ATOM   11409 C  CZ3 . TRP D 2 301 ? 324.428 273.758 238.992 1.00 70.51  ? 299 TRP D CZ3 1 
ATOM   11410 C  CH2 . TRP D 2 301 ? 323.223 273.671 239.698 1.00 71.81  ? 299 TRP D CH2 1 
ATOM   11411 N  N   . GLY E 1 32  ? 251.177 240.870 236.896 1.00 64.62  ? 32  GLY E N   1 
ATOM   11412 C  CA  . GLY E 1 32  ? 251.449 242.182 237.450 1.00 66.17  ? 32  GLY E CA  1 
ATOM   11413 C  C   . GLY E 1 32  ? 251.408 243.287 236.413 1.00 64.27  ? 32  GLY E C   1 
ATOM   11414 O  O   . GLY E 1 32  ? 250.501 243.336 235.583 1.00 65.15  ? 32  GLY E O   1 
ATOM   11415 N  N   . GLY E 1 33  ? 252.394 244.181 236.465 1.00 59.51  ? 33  GLY E N   1 
ATOM   11416 C  CA  . GLY E 1 33  ? 252.501 245.276 235.529 1.00 61.28  ? 33  GLY E CA  1 
ATOM   11417 C  C   . GLY E 1 33  ? 252.760 246.579 236.251 1.00 64.39  ? 33  GLY E C   1 
ATOM   11418 O  O   . GLY E 1 33  ? 253.243 246.599 237.389 1.00 59.31  ? 33  GLY E O   1 
ATOM   11419 N  N   . GLU E 1 34  ? 252.431 247.679 235.578 1.00 69.37  ? 34  GLU E N   1 
ATOM   11420 C  CA  . GLU E 1 34  ? 252.672 249.010 236.106 1.00 64.75  ? 34  GLU E CA  1 
ATOM   11421 C  C   . GLU E 1 34  ? 251.436 249.525 236.839 1.00 63.15  ? 34  GLU E C   1 
ATOM   11422 O  O   . GLU E 1 34  ? 250.434 248.824 236.999 1.00 62.46  ? 34  GLU E O   1 
ATOM   11423 C  CB  . GLU E 1 34  ? 253.081 249.961 234.983 1.00 59.64  ? 34  GLU E CB  1 
ATOM   11424 C  CG  . GLU E 1 34  ? 254.330 249.534 234.234 1.00 65.25  ? 34  GLU E CG  1 
ATOM   11425 C  CD  . GLU E 1 34  ? 255.604 249.945 234.943 1.00 72.83  ? 34  GLU E CD  1 
ATOM   11426 O  OE1 . GLU E 1 34  ? 255.583 250.067 236.185 1.00 71.73  ? 34  GLU E OE1 1 
ATOM   11427 O  OE2 . GLU E 1 34  ? 256.628 250.149 234.258 1.00 75.90  ? 34  GLU E OE2 1 
ATOM   11428 N  N   . LEU E 1 35  ? 251.509 250.776 237.292 1.00 61.65  ? 35  LEU E N   1 
ATOM   11429 C  CA  . LEU E 1 35  ? 250.437 251.387 238.074 1.00 56.14  ? 35  LEU E CA  1 
ATOM   11430 C  C   . LEU E 1 35  ? 249.556 252.224 237.151 1.00 55.43  ? 35  LEU E C   1 
ATOM   11431 O  O   . LEU E 1 35  ? 249.645 253.450 237.095 1.00 55.48  ? 35  LEU E O   1 
ATOM   11432 C  CB  . LEU E 1 35  ? 251.012 252.221 239.213 1.00 43.22  ? 35  LEU E CB  1 
ATOM   11433 C  CG  . LEU E 1 35  ? 249.978 253.026 240.000 1.00 40.34  ? 35  LEU E CG  1 
ATOM   11434 C  CD1 . LEU E 1 35  ? 249.155 252.110 240.889 1.00 35.77  ? 35  LEU E CD1 1 
ATOM   11435 C  CD2 . LEU E 1 35  ? 250.648 254.117 240.820 1.00 40.46  ? 35  LEU E CD2 1 
ATOM   11436 N  N   . THR E 1 36  ? 248.692 251.538 236.411 1.00 54.94  ? 36  THR E N   1 
ATOM   11437 C  CA  . THR E 1 36  ? 247.616 252.208 235.696 1.00 59.49  ? 36  THR E CA  1 
ATOM   11438 C  C   . THR E 1 36  ? 246.509 252.528 236.699 1.00 56.12  ? 36  THR E C   1 
ATOM   11439 O  O   . THR E 1 36  ? 246.668 252.352 237.910 1.00 53.20  ? 36  THR E O   1 
ATOM   11440 C  CB  . THR E 1 36  ? 247.128 251.352 234.530 1.00 61.27  ? 36  THR E CB  1 
ATOM   11441 O  OG1 . THR E 1 36  ? 246.494 250.169 235.030 1.00 60.38  ? 36  THR E OG1 1 
ATOM   11442 C  CG2 . THR E 1 36  ? 248.295 250.955 233.639 1.00 59.44  ? 36  THR E CG2 1 
ATOM   11443 N  N   . GLY E 1 37  ? 245.371 253.011 236.215 1.00 52.80  ? 37  GLY E N   1 
ATOM   11444 C  CA  . GLY E 1 37  ? 244.254 253.363 237.070 1.00 45.53  ? 37  GLY E CA  1 
ATOM   11445 C  C   . GLY E 1 37  ? 243.077 252.432 236.856 1.00 50.81  ? 37  GLY E C   1 
ATOM   11446 O  O   . GLY E 1 37  ? 242.876 251.906 235.759 1.00 56.10  ? 37  GLY E O   1 
ATOM   11447 N  N   . ALA E 1 38  ? 242.299 252.228 237.916 1.00 46.16  ? 38  ALA E N   1 
ATOM   11448 C  CA  . ALA E 1 38  ? 241.047 251.480 237.843 1.00 45.66  ? 38  ALA E CA  1 
ATOM   11449 C  C   . ALA E 1 38  ? 239.929 252.507 237.700 1.00 49.53  ? 38  ALA E C   1 
ATOM   11450 O  O   . ALA E 1 38  ? 239.306 252.920 238.678 1.00 48.30  ? 38  ALA E O   1 
ATOM   11451 C  CB  . ALA E 1 38  ? 240.861 250.595 239.069 1.00 38.74  ? 38  ALA E CB  1 
ATOM   11452 N  N   . LYS E 1 39  ? 239.678 252.919 236.461 1.00 51.76  ? 39  LYS E N   1 
ATOM   11453 C  CA  . LYS E 1 39  ? 238.712 253.973 236.200 1.00 52.57  ? 39  LYS E CA  1 
ATOM   11454 C  C   . LYS E 1 39  ? 237.286 253.471 236.411 1.00 54.21  ? 39  LYS E C   1 
ATOM   11455 O  O   . LYS E 1 39  ? 236.997 252.274 236.339 1.00 57.91  ? 39  LYS E O   1 
ATOM   11456 C  CB  . LYS E 1 39  ? 238.870 254.503 234.776 1.00 59.28  ? 39  LYS E CB  1 
ATOM   11457 C  CG  . LYS E 1 39  ? 239.967 255.541 234.616 1.00 57.94  ? 39  LYS E CG  1 
ATOM   11458 C  CD  . LYS E 1 39  ? 240.713 255.352 233.306 1.00 63.47  ? 39  LYS E CD  1 
ATOM   11459 C  CE  . LYS E 1 39  ? 239.752 255.070 232.163 1.00 61.84  ? 39  LYS E CE  1 
ATOM   11460 N  NZ  . LYS E 1 39  ? 239.174 256.323 231.604 1.00 68.23  ? 39  LYS E NZ  1 
ATOM   11461 N  N   . LEU E 1 40  ? 236.391 254.414 236.679 1.00 54.35  ? 40  LEU E N   1 
ATOM   11462 C  CA  . LEU E 1 40  ? 234.973 254.139 236.841 1.00 51.96  ? 40  LEU E CA  1 
ATOM   11463 C  C   . LEU E 1 40  ? 234.221 254.479 235.559 1.00 57.95  ? 40  LEU E C   1 
ATOM   11464 O  O   . LEU E 1 40  ? 234.700 255.234 234.710 1.00 57.17  ? 40  LEU E O   1 
ATOM   11465 C  CB  . LEU E 1 40  ? 234.401 254.935 238.017 1.00 46.71  ? 40  LEU E CB  1 
ATOM   11466 C  CG  . LEU E 1 40  ? 234.962 254.588 239.397 1.00 43.12  ? 40  LEU E CG  1 
ATOM   11467 C  CD1 . LEU E 1 40  ? 234.384 255.503 240.461 1.00 35.24  ? 40  LEU E CD1 1 
ATOM   11468 C  CD2 . LEU E 1 40  ? 234.697 253.132 239.740 1.00 38.24  ? 40  LEU E CD2 1 
ATOM   11469 N  N   . SER E 1 41  ? 233.028 253.907 235.428 1.00 60.80  ? 41  SER E N   1 
ATOM   11470 C  CA  . SER E 1 41  ? 232.204 254.167 234.256 1.00 67.97  ? 41  SER E CA  1 
ATOM   11471 C  C   . SER E 1 41  ? 231.625 255.575 234.323 1.00 72.00  ? 41  SER E C   1 
ATOM   11472 O  O   . SER E 1 41  ? 231.055 255.976 235.342 1.00 70.45  ? 41  SER E O   1 
ATOM   11473 C  CB  . SER E 1 41  ? 231.085 253.133 234.156 1.00 72.57  ? 41  SER E CB  1 
ATOM   11474 O  OG  . SER E 1 41  ? 230.550 252.840 235.435 1.00 75.08  ? 41  SER E OG  1 
ATOM   11475 N  N   . SER E 1 42  ? 231.764 256.322 233.230 1.00 76.38  ? 42  SER E N   1 
ATOM   11476 C  CA  . SER E 1 42  ? 231.334 257.713 233.216 1.00 78.01  ? 42  SER E CA  1 
ATOM   11477 C  C   . SER E 1 42  ? 229.830 257.818 233.436 1.00 81.13  ? 42  SER E C   1 
ATOM   11478 O  O   . SER E 1 42  ? 229.056 256.970 232.983 1.00 80.95  ? 42  SER E O   1 
ATOM   11479 C  CB  . SER E 1 42  ? 231.718 258.371 231.891 1.00 81.55  ? 42  SER E CB  1 
ATOM   11480 O  OG  . SER E 1 42  ? 230.615 258.403 231.004 1.00 86.93  ? 42  SER E OG  1 
ATOM   11481 N  N   . TRP E 1 43  ? 229.420 258.871 234.136 1.00 82.85  ? 43  TRP E N   1 
ATOM   11482 C  CA  . TRP E 1 43  ? 228.022 259.130 234.437 1.00 87.41  ? 43  TRP E CA  1 
ATOM   11483 C  C   . TRP E 1 43  ? 227.512 260.304 233.611 1.00 92.28  ? 43  TRP E C   1 
ATOM   11484 O  O   . TRP E 1 43  ? 228.286 261.105 233.079 1.00 92.12  ? 43  TRP E O   1 
ATOM   11485 C  CB  . TRP E 1 43  ? 227.828 259.422 235.929 1.00 83.40  ? 43  TRP E CB  1 
ATOM   11486 C  CG  . TRP E 1 43  ? 228.187 258.275 236.819 1.00 81.08  ? 43  TRP E CG  1 
ATOM   11487 C  CD1 . TRP E 1 43  ? 228.407 256.983 236.442 1.00 82.58  ? 43  TRP E CD1 1 
ATOM   11488 C  CD2 . TRP E 1 43  ? 228.366 258.315 238.239 1.00 77.58  ? 43  TRP E CD2 1 
ATOM   11489 N  NE1 . TRP E 1 43  ? 228.714 256.216 237.539 1.00 82.34  ? 43  TRP E NE1 1 
ATOM   11490 C  CE2 . TRP E 1 43  ? 228.694 257.010 238.655 1.00 79.21  ? 43  TRP E CE2 1 
ATOM   11491 C  CE3 . TRP E 1 43  ? 228.279 259.326 239.200 1.00 70.56  ? 43  TRP E CE3 1 
ATOM   11492 C  CZ2 . TRP E 1 43  ? 228.939 256.691 239.987 1.00 72.33  ? 43  TRP E CZ2 1 
ATOM   11493 C  CZ3 . TRP E 1 43  ? 228.521 259.006 240.524 1.00 70.17  ? 43  TRP E CZ3 1 
ATOM   11494 C  CH2 . TRP E 1 43  ? 228.847 257.701 240.905 1.00 70.64  ? 43  TRP E CH2 1 
ATOM   11495 N  N   . ASN E 1 44  ? 226.189 260.396 233.509 1.00 96.32  ? 44  ASN E N   1 
ATOM   11496 C  CA  . ASN E 1 44  ? 225.518 261.491 232.822 1.00 97.52  ? 44  ASN E CA  1 
ATOM   11497 C  C   . ASN E 1 44  ? 224.794 262.353 233.846 1.00 96.65  ? 44  ASN E C   1 
ATOM   11498 O  O   . ASN E 1 44  ? 224.006 261.840 234.648 1.00 97.02  ? 44  ASN E O   1 
ATOM   11499 C  CB  . ASN E 1 44  ? 224.531 260.965 231.777 1.00 101.35 ? 44  ASN E CB  1 
ATOM   11500 C  CG  . ASN E 1 44  ? 223.947 262.070 230.920 1.00 103.80 ? 44  ASN E CG  1 
ATOM   11501 O  OD1 . ASN E 1 44  ? 222.731 262.162 230.748 1.00 104.09 ? 44  ASN E OD1 1 
ATOM   11502 N  ND2 . ASN E 1 44  ? 224.813 262.917 230.376 1.00 100.99 ? 44  ASN E ND2 1 
ATOM   11503 N  N   . GLU E 1 45  ? 225.059 263.659 233.816 1.00 93.93  ? 45  GLU E N   1 
ATOM   11504 C  CA  . GLU E 1 45  ? 224.500 264.570 234.803 1.00 90.58  ? 45  GLU E CA  1 
ATOM   11505 C  C   . GLU E 1 45  ? 223.286 265.274 234.220 1.00 88.50  ? 45  GLU E C   1 
ATOM   11506 O  O   . GLU E 1 45  ? 223.439 266.090 233.298 1.00 90.17  ? 45  GLU E O   1 
ATOM   11507 C  CB  . GLU E 1 45  ? 225.547 265.590 235.243 1.00 90.18  ? 45  GLU E CB  1 
ATOM   11508 C  CG  . GLU E 1 45  ? 224.970 266.901 235.753 1.00 89.73  ? 45  GLU E CG  1 
ATOM   11509 C  CD  . GLU E 1 45  ? 224.599 266.843 237.221 1.00 89.90  ? 45  GLU E CD  1 
ATOM   11510 O  OE1 . GLU E 1 45  ? 224.661 265.743 237.808 1.00 89.50  ? 45  GLU E OE1 1 
ATOM   11511 O  OE2 . GLU E 1 45  ? 224.252 267.899 237.790 1.00 79.06  ? 45  GLU E OE2 1 
ATOM   11512 N  N   . PRO E 1 46  ? 222.074 265.002 234.711 1.00 84.55  ? 46  PRO E N   1 
ATOM   11513 C  CA  . PRO E 1 46  ? 220.877 265.679 234.188 1.00 81.68  ? 46  PRO E CA  1 
ATOM   11514 C  C   . PRO E 1 46  ? 220.746 267.073 234.784 1.00 77.38  ? 46  PRO E C   1 
ATOM   11515 O  O   . PRO E 1 46  ? 220.530 267.228 235.987 1.00 72.90  ? 46  PRO E O   1 
ATOM   11516 C  CB  . PRO E 1 46  ? 219.726 264.764 234.636 1.00 79.77  ? 46  PRO E CB  1 
ATOM   11517 C  CG  . PRO E 1 46  ? 220.373 263.560 235.294 1.00 84.30  ? 46  PRO E CG  1 
ATOM   11518 C  CD  . PRO E 1 46  ? 221.736 263.986 235.717 1.00 85.95  ? 46  PRO E CD  1 
ATOM   11519 N  N   . SER E 1 47  ? 220.876 268.088 233.938 1.00 74.07  ? 47  SER E N   1 
ATOM   11520 C  CA  . SER E 1 47  ? 220.718 269.461 234.400 1.00 67.63  ? 47  SER E CA  1 
ATOM   11521 C  C   . SER E 1 47  ? 219.263 269.708 234.780 1.00 65.39  ? 47  SER E C   1 
ATOM   11522 O  O   . SER E 1 47  ? 218.365 269.464 233.966 1.00 64.08  ? 47  SER E O   1 
ATOM   11523 C  CB  . SER E 1 47  ? 221.160 270.446 233.322 1.00 63.11  ? 47  SER E CB  1 
ATOM   11524 O  OG  . SER E 1 47  ? 220.542 271.709 233.503 1.00 60.53  ? 47  SER E OG  1 
ATOM   11525 N  N   . PRO E 1 48  ? 218.987 270.187 235.990 1.00 58.51  ? 48  PRO E N   1 
ATOM   11526 C  CA  . PRO E 1 48  ? 217.593 270.351 236.414 1.00 50.13  ? 48  PRO E CA  1 
ATOM   11527 C  C   . PRO E 1 48  ? 216.887 271.441 235.625 1.00 49.39  ? 48  PRO E C   1 
ATOM   11528 O  O   . PRO E 1 48  ? 217.486 272.433 235.207 1.00 50.40  ? 48  PRO E O   1 
ATOM   11529 C  CB  . PRO E 1 48  ? 217.708 270.725 237.899 1.00 46.57  ? 48  PRO E CB  1 
ATOM   11530 C  CG  . PRO E 1 48  ? 219.157 270.542 238.263 1.00 44.01  ? 48  PRO E CG  1 
ATOM   11531 C  CD  . PRO E 1 48  ? 219.932 270.682 237.000 1.00 47.91  ? 48  PRO E CD  1 
ATOM   11532 N  N   . PHE E 1 49  ? 215.588 271.241 235.430 1.00 48.21  ? 49  PHE E N   1 
ATOM   11533 C  CA  . PHE E 1 49  ? 214.763 272.206 234.720 1.00 45.40  ? 49  PHE E CA  1 
ATOM   11534 C  C   . PHE E 1 49  ? 214.376 273.356 235.640 1.00 45.51  ? 49  PHE E C   1 
ATOM   11535 O  O   . PHE E 1 49  ? 214.002 273.146 236.798 1.00 44.84  ? 49  PHE E O   1 
ATOM   11536 C  CB  . PHE E 1 49  ? 213.511 271.525 234.169 1.00 41.35  ? 49  PHE E CB  1 
ATOM   11537 C  CG  . PHE E 1 49  ? 212.540 272.470 233.532 1.00 47.28  ? 49  PHE E CG  1 
ATOM   11538 C  CD1 . PHE E 1 49  ? 212.753 272.938 232.247 1.00 48.71  ? 49  PHE E CD1 1 
ATOM   11539 C  CD2 . PHE E 1 49  ? 211.413 272.889 234.215 1.00 48.71  ? 49  PHE E CD2 1 
ATOM   11540 C  CE1 . PHE E 1 49  ? 211.862 273.809 231.659 1.00 55.56  ? 49  PHE E CE1 1 
ATOM   11541 C  CE2 . PHE E 1 49  ? 210.519 273.760 233.633 1.00 43.34  ? 49  PHE E CE2 1 
ATOM   11542 C  CZ  . PHE E 1 49  ? 210.742 274.220 232.353 1.00 52.62  ? 49  PHE E CZ  1 
ATOM   11543 N  N   . GLY E 1 50  ? 214.470 274.577 235.120 1.00 40.85  ? 50  GLY E N   1 
ATOM   11544 C  CA  . GLY E 1 50  ? 214.131 275.747 235.902 1.00 35.39  ? 50  GLY E CA  1 
ATOM   11545 C  C   . GLY E 1 50  ? 215.201 276.203 236.865 1.00 31.96  ? 50  GLY E C   1 
ATOM   11546 O  O   . GLY E 1 50  ? 214.907 276.990 237.770 1.00 32.83  ? 50  GLY E O   1 
ATOM   11547 N  N   . MET E 1 51  ? 216.435 275.734 236.703 1.00 31.46  ? 51  MET E N   1 
ATOM   11548 C  CA  . MET E 1 51  ? 217.526 276.075 237.601 1.00 27.80  ? 51  MET E CA  1 
ATOM   11549 C  C   . MET E 1 51  ? 218.680 276.678 236.813 1.00 29.76  ? 51  MET E C   1 
ATOM   11550 O  O   . MET E 1 51  ? 218.833 276.448 235.612 1.00 35.19  ? 51  MET E O   1 
ATOM   11551 C  CB  . MET E 1 51  ? 218.019 274.850 238.383 1.00 30.63  ? 51  MET E CB  1 
ATOM   11552 C  CG  . MET E 1 51  ? 216.932 274.107 239.137 1.00 30.76  ? 51  MET E CG  1 
ATOM   11553 S  SD  . MET E 1 51  ? 217.603 272.956 240.348 1.00 40.89  ? 51  MET E SD  1 
ATOM   11554 C  CE  . MET E 1 51  ? 217.238 273.813 241.874 1.00 20.00  ? 51  MET E CE  1 
ATOM   11555 N  N   . ILE E 1 52  ? 219.492 277.461 237.517 1.00 26.63  ? 52  ILE E N   1 
ATOM   11556 C  CA  . ILE E 1 52  ? 220.737 277.996 236.987 1.00 27.37  ? 52  ILE E CA  1 
ATOM   11557 C  C   . ILE E 1 52  ? 221.881 277.468 237.844 1.00 26.06  ? 52  ILE E C   1 
ATOM   11558 O  O   . ILE E 1 52  ? 221.676 276.932 238.933 1.00 31.44  ? 52  ILE E O   1 
ATOM   11559 C  CB  . ILE E 1 52  ? 220.747 279.538 236.937 1.00 27.57  ? 52  ILE E CB  1 
ATOM   11560 C  CG1 . ILE E 1 52  ? 220.258 280.127 238.260 1.00 24.91  ? 52  ILE E CG1 1 
ATOM   11561 C  CG2 . ILE E 1 52  ? 219.892 280.039 235.789 1.00 27.07  ? 52  ILE E CG2 1 
ATOM   11562 C  CD1 . ILE E 1 52  ? 221.368 280.528 239.197 1.00 23.66  ? 52  ILE E CD1 1 
ATOM   11563 N  N   . GLN E 1 53  ? 223.097 277.620 237.334 1.00 27.14  ? 53  GLN E N   1 
ATOM   11564 C  CA  . GLN E 1 53  ? 224.288 277.098 237.990 1.00 26.06  ? 53  GLN E CA  1 
ATOM   11565 C  C   . GLN E 1 53  ? 225.022 278.238 238.684 1.00 26.65  ? 53  GLN E C   1 
ATOM   11566 O  O   . GLN E 1 53  ? 225.398 279.223 238.040 1.00 28.34  ? 53  GLN E O   1 
ATOM   11567 C  CB  . GLN E 1 53  ? 225.200 276.401 236.981 1.00 32.13  ? 53  GLN E CB  1 
ATOM   11568 C  CG  . GLN E 1 53  ? 226.612 276.159 237.481 1.00 33.13  ? 53  GLN E CG  1 
ATOM   11569 C  CD  . GLN E 1 53  ? 226.747 274.850 238.231 1.00 36.10  ? 53  GLN E CD  1 
ATOM   11570 O  OE1 . GLN E 1 53  ? 227.102 274.830 239.408 1.00 39.18  ? 53  GLN E OE1 1 
ATOM   11571 N  NE2 . GLN E 1 53  ? 226.464 273.746 237.549 1.00 40.09  ? 53  GLN E NE2 1 
ATOM   11572 N  N   . VAL E 1 54  ? 225.219 278.102 239.989 1.00 27.63  ? 54  VAL E N   1 
ATOM   11573 C  CA  . VAL E 1 54  ? 225.961 279.062 240.797 1.00 25.73  ? 54  VAL E CA  1 
ATOM   11574 C  C   . VAL E 1 54  ? 227.362 278.499 241.008 1.00 29.06  ? 54  VAL E C   1 
ATOM   11575 O  O   . VAL E 1 54  ? 227.499 277.423 241.616 1.00 27.35  ? 54  VAL E O   1 
ATOM   11576 C  CB  . VAL E 1 54  ? 225.266 279.323 242.141 1.00 20.29  ? 54  VAL E CB  1 
ATOM   11577 C  CG1 . VAL E 1 54  ? 226.156 280.157 243.041 1.00 19.81  ? 54  VAL E CG1 1 
ATOM   11578 C  CG2 . VAL E 1 54  ? 223.924 280.001 241.922 1.00 21.40  ? 54  VAL E CG2 1 
ATOM   11579 N  N   . PRO E 1 55  ? 228.406 279.166 240.529 1.00 27.75  ? 55  PRO E N   1 
ATOM   11580 C  CA  . PRO E 1 55  ? 229.758 278.615 240.642 1.00 20.52  ? 55  PRO E CA  1 
ATOM   11581 C  C   . PRO E 1 55  ? 230.271 278.647 242.071 1.00 24.38  ? 55  PRO E C   1 
ATOM   11582 O  O   . PRO E 1 55  ? 229.790 279.393 242.926 1.00 24.69  ? 55  PRO E O   1 
ATOM   11583 C  CB  . PRO E 1 55  ? 230.585 279.536 239.741 1.00 22.41  ? 55  PRO E CB  1 
ATOM   11584 C  CG  . PRO E 1 55  ? 229.851 280.830 239.781 1.00 22.34  ? 55  PRO E CG  1 
ATOM   11585 C  CD  . PRO E 1 55  ? 228.396 280.467 239.839 1.00 19.98  ? 55  PRO E CD  1 
ATOM   11586 N  N   . ARG E 1 56  ? 231.269 277.805 242.321 1.00 22.84  ? 56  ARG E N   1 
ATOM   11587 C  CA  . ARG E 1 56  ? 231.970 277.837 243.594 1.00 21.60  ? 56  ARG E CA  1 
ATOM   11588 C  C   . ARG E 1 56  ? 232.706 279.162 243.749 1.00 22.45  ? 56  ARG E C   1 
ATOM   11589 O  O   . ARG E 1 56  ? 233.116 279.788 242.768 1.00 27.19  ? 56  ARG E O   1 
ATOM   11590 C  CB  . ARG E 1 56  ? 232.956 276.673 243.685 1.00 24.27  ? 56  ARG E CB  1 
ATOM   11591 C  CG  . ARG E 1 56  ? 234.251 276.919 242.934 1.00 24.00  ? 56  ARG E CG  1 
ATOM   11592 C  CD  . ARG E 1 56  ? 235.239 275.784 243.118 1.00 26.55  ? 56  ARG E CD  1 
ATOM   11593 N  NE  . ARG E 1 56  ? 234.745 274.535 242.554 1.00 36.55  ? 56  ARG E NE  1 
ATOM   11594 C  CZ  . ARG E 1 56  ? 235.316 273.894 241.544 1.00 39.40  ? 56  ARG E CZ  1 
ATOM   11595 N  NH1 . ARG E 1 56  ? 236.408 274.358 240.958 1.00 29.02  ? 56  ARG E NH1 1 
ATOM   11596 N  NH2 . ARG E 1 56  ? 234.777 272.760 241.109 1.00 43.60  ? 56  ARG E NH2 1 
ATOM   11597 N  N   . GLY E 1 57  ? 232.870 279.595 244.991 1.00 18.21  ? 57  GLY E N   1 
ATOM   11598 C  CA  . GLY E 1 57  ? 233.538 280.859 245.223 1.00 17.97  ? 57  GLY E CA  1 
ATOM   11599 C  C   . GLY E 1 57  ? 233.606 281.182 246.696 1.00 19.13  ? 57  GLY E C   1 
ATOM   11600 O  O   . GLY E 1 57  ? 233.410 280.319 247.553 1.00 21.81  ? 57  GLY E O   1 
ATOM   11601 N  N   . SER E 1 58  ? 233.899 282.449 246.976 1.00 19.65  ? 58  SER E N   1 
ATOM   11602 C  CA  . SER E 1 58  ? 234.064 282.933 248.336 1.00 18.45  ? 58  SER E CA  1 
ATOM   11603 C  C   . SER E 1 58  ? 233.366 284.275 248.475 1.00 21.77  ? 58  SER E C   1 
ATOM   11604 O  O   . SER E 1 58  ? 233.216 285.017 247.501 1.00 26.44  ? 58  SER E O   1 
ATOM   11605 C  CB  . SER E 1 58  ? 235.547 283.066 248.708 1.00 22.68  ? 58  SER E CB  1 
ATOM   11606 O  OG  . SER E 1 58  ? 235.705 283.585 250.016 1.00 27.41  ? 58  SER E OG  1 
ATOM   11607 N  N   . ILE E 1 59  ? 232.937 284.581 249.698 1.00 19.47  ? 59  ILE E N   1 
ATOM   11608 C  CA  . ILE E 1 59  ? 232.259 285.843 249.968 1.00 17.80  ? 59  ILE E CA  1 
ATOM   11609 C  C   . ILE E 1 59  ? 232.351 286.134 251.455 1.00 22.95  ? 59  ILE E C   1 
ATOM   11610 O  O   . ILE E 1 59  ? 232.463 285.220 252.275 1.00 24.23  ? 59  ILE E O   1 
ATOM   11611 C  CB  . ILE E 1 59  ? 230.787 285.804 249.482 1.00 23.28  ? 59  ILE E CB  1 
ATOM   11612 C  CG1 . ILE E 1 59  ? 230.270 287.220 249.221 1.00 22.90  ? 59  ILE E CG1 1 
ATOM   11613 C  CG2 . ILE E 1 59  ? 229.908 285.087 250.492 1.00 20.40  ? 59  ILE E CG2 1 
ATOM   11614 C  CD1 . ILE E 1 59  ? 228.926 287.262 248.539 1.00 20.09  ? 59  ILE E CD1 1 
ATOM   11615 N  N   . VAL E 1 60  ? 232.297 287.417 251.803 1.00 26.49  ? 60  VAL E N   1 
ATOM   11616 C  CA  . VAL E 1 60  ? 232.267 287.848 253.195 1.00 26.04  ? 60  VAL E CA  1 
ATOM   11617 C  C   . VAL E 1 60  ? 230.800 288.024 253.575 1.00 28.74  ? 60  VAL E C   1 
ATOM   11618 O  O   . VAL E 1 60  ? 230.177 289.035 253.250 1.00 37.03  ? 60  VAL E O   1 
ATOM   11619 C  CB  . VAL E 1 60  ? 233.068 289.132 253.411 1.00 24.99  ? 60  VAL E CB  1 
ATOM   11620 C  CG1 . VAL E 1 60  ? 233.013 289.546 254.870 1.00 30.50  ? 60  VAL E CG1 1 
ATOM   11621 C  CG2 . VAL E 1 60  ? 234.507 288.942 252.964 1.00 23.37  ? 60  VAL E CG2 1 
ATOM   11622 N  N   . LEU E 1 61  ? 230.245 287.026 254.258 1.00 31.16  ? 61  LEU E N   1 
ATOM   11623 C  CA  . LEU E 1 61  ? 228.880 287.120 254.748 1.00 27.41  ? 61  LEU E CA  1 
ATOM   11624 C  C   . LEU E 1 61  ? 228.774 288.224 255.791 1.00 32.75  ? 61  LEU E C   1 
ATOM   11625 O  O   . LEU E 1 61  ? 229.690 288.447 256.585 1.00 40.55  ? 61  LEU E O   1 
ATOM   11626 C  CB  . LEU E 1 61  ? 228.446 285.790 255.363 1.00 24.76  ? 61  LEU E CB  1 
ATOM   11627 C  CG  . LEU E 1 61  ? 228.481 284.545 254.480 1.00 26.06  ? 61  LEU E CG  1 
ATOM   11628 C  CD1 . LEU E 1 61  ? 228.204 283.310 255.318 1.00 20.56  ? 61  LEU E CD1 1 
ATOM   11629 C  CD2 . LEU E 1 61  ? 227.487 284.659 253.340 1.00 23.68  ? 61  LEU E CD2 1 
ATOM   11630 N  N   . GLY E 1 62  ? 227.635 288.906 255.794 1.00 35.73  ? 62  GLY E N   1 
ATOM   11631 C  CA  . GLY E 1 62  ? 227.398 289.971 256.744 1.00 38.21  ? 62  GLY E CA  1 
ATOM   11632 C  C   . GLY E 1 62  ? 227.749 291.337 256.197 1.00 47.22  ? 62  GLY E C   1 
ATOM   11633 O  O   . GLY E 1 62  ? 228.231 291.505 255.074 1.00 48.17  ? 62  GLY E O   1 
ATOM   11634 N  N   . ASN E 1 63  ? 227.492 292.342 257.028 1.00 56.92  ? 63  ASN E N   1 
ATOM   11635 C  CA  . ASN E 1 63  ? 227.742 293.733 256.688 1.00 58.05  ? 63  ASN E CA  1 
ATOM   11636 C  C   . ASN E 1 63  ? 228.877 294.277 257.544 1.00 63.06  ? 63  ASN E C   1 
ATOM   11637 O  O   . ASN E 1 63  ? 228.919 294.048 258.757 1.00 62.42  ? 63  ASN E O   1 
ATOM   11638 C  CB  . ASN E 1 63  ? 226.481 294.580 256.881 1.00 56.06  ? 63  ASN E CB  1 
ATOM   11639 C  CG  . ASN E 1 63  ? 226.023 294.623 258.326 1.00 62.74  ? 63  ASN E CG  1 
ATOM   11640 O  OD1 . ASN E 1 63  ? 226.306 293.716 259.108 1.00 63.56  ? 63  ASN E OD1 1 
ATOM   11641 N  ND2 . ASN E 1 63  ? 225.305 295.680 258.687 1.00 67.42  ? 63  ASN E ND2 1 
ATOM   11642 N  N   . LYS E 1 64  ? 229.801 294.995 256.903 1.00 69.15  ? 64  LYS E N   1 
ATOM   11643 C  CA  . LYS E 1 64  ? 230.938 295.552 257.627 1.00 68.52  ? 64  LYS E CA  1 
ATOM   11644 C  C   . LYS E 1 64  ? 230.533 296.737 258.496 1.00 66.89  ? 64  LYS E C   1 
ATOM   11645 O  O   . LYS E 1 64  ? 231.108 296.938 259.571 1.00 66.51  ? 64  LYS E O   1 
ATOM   11646 C  CB  . LYS E 1 64  ? 232.035 295.964 256.645 1.00 69.76  ? 64  LYS E CB  1 
ATOM   11647 C  CG  . LYS E 1 64  ? 232.573 294.825 255.786 1.00 73.48  ? 64  LYS E CG  1 
ATOM   11648 C  CD  . LYS E 1 64  ? 231.679 294.559 254.580 1.00 72.88  ? 64  LYS E CD  1 
ATOM   11649 C  CE  . LYS E 1 64  ? 232.068 293.268 253.873 1.00 62.30  ? 64  LYS E CE  1 
ATOM   11650 N  NZ  . LYS E 1 64  ? 230.881 292.510 253.381 1.00 48.03  ? 64  LYS E NZ  1 
ATOM   11651 N  N   . GLU E 1 65  ? 229.557 297.524 258.055 1.00 65.37  ? 65  GLU E N   1 
ATOM   11652 C  CA  . GLU E 1 65  ? 229.127 298.723 258.761 1.00 68.83  ? 65  GLU E CA  1 
ATOM   11653 C  C   . GLU E 1 65  ? 227.694 298.563 259.250 1.00 71.95  ? 65  GLU E C   1 
ATOM   11654 O  O   . GLU E 1 65  ? 226.839 298.029 258.536 1.00 72.32  ? 65  GLU E O   1 
ATOM   11655 C  CB  . GLU E 1 65  ? 229.238 299.957 257.862 1.00 71.63  ? 65  GLU E CB  1 
ATOM   11656 C  CG  . GLU E 1 65  ? 228.364 299.903 256.620 1.00 82.21  ? 65  GLU E CG  1 
ATOM   11657 C  CD  . GLU E 1 65  ? 229.129 299.443 255.394 1.00 88.11  ? 65  GLU E CD  1 
ATOM   11658 O  OE1 . GLU E 1 65  ? 230.371 299.577 255.383 1.00 87.12  ? 65  GLU E OE1 1 
ATOM   11659 O  OE2 . GLU E 1 65  ? 228.490 298.947 254.441 1.00 89.38  ? 65  GLU E OE2 1 
ATOM   11660 N  N   . ALA E 1 66  ? 227.439 299.032 260.468 1.00 69.03  ? 66  ALA E N   1 
ATOM   11661 C  CA  . ALA E 1 66  ? 226.135 298.907 261.099 1.00 65.78  ? 66  ALA E CA  1 
ATOM   11662 C  C   . ALA E 1 66  ? 225.299 300.170 260.890 1.00 68.39  ? 66  ALA E C   1 
ATOM   11663 O  O   . ALA E 1 66  ? 225.790 301.214 260.457 1.00 68.40  ? 66  ALA E O   1 
ATOM   11664 C  CB  . ALA E 1 66  ? 226.292 298.616 262.591 1.00 65.24  ? 66  ALA E CB  1 
ATOM   11665 N  N   . ASP E 1 67  ? 224.006 300.055 261.207 1.00 67.55  ? 67  ASP E N   1 
ATOM   11666 C  CA  . ASP E 1 67  ? 223.099 301.191 261.072 1.00 63.93  ? 67  ASP E CA  1 
ATOM   11667 C  C   . ASP E 1 67  ? 223.331 302.223 262.170 1.00 69.12  ? 67  ASP E C   1 
ATOM   11668 O  O   . ASP E 1 67  ? 223.266 303.432 261.919 1.00 71.93  ? 67  ASP E O   1 
ATOM   11669 C  CB  . ASP E 1 67  ? 221.647 300.711 261.095 1.00 58.12  ? 67  ASP E CB  1 
ATOM   11670 C  CG  . ASP E 1 67  ? 221.411 299.493 260.215 1.00 60.77  ? 67  ASP E CG  1 
ATOM   11671 O  OD1 . ASP E 1 67  ? 222.109 298.472 260.392 1.00 63.14  ? 67  ASP E OD1 1 
ATOM   11672 O  OD2 . ASP E 1 67  ? 220.514 299.555 259.350 1.00 57.23  ? 67  ASP E OD2 1 
ATOM   11673 N  N   . SER E 1 68  ? 223.583 301.761 263.395 1.00 69.20  ? 68  SER E N   1 
ATOM   11674 C  CA  . SER E 1 68  ? 223.849 302.618 264.545 1.00 70.47  ? 68  SER E CA  1 
ATOM   11675 C  C   . SER E 1 68  ? 222.584 303.289 265.066 1.00 65.29  ? 68  SER E C   1 
ATOM   11676 O  O   . SER E 1 68  ? 222.616 303.959 266.102 1.00 68.29  ? 68  SER E O   1 
ATOM   11677 C  CB  . SER E 1 68  ? 224.894 303.682 264.205 1.00 74.70  ? 68  SER E CB  1 
ATOM   11678 O  OG  . SER E 1 68  ? 225.170 304.478 265.345 1.00 77.94  ? 68  SER E OG  1 
ATOM   11679 N  N   . LEU E 1 69  ? 221.466 303.120 264.358 1.00 57.72  ? 69  LEU E N   1 
ATOM   11680 C  CA  . LEU E 1 69  ? 220.159 303.471 264.891 1.00 48.13  ? 69  LEU E CA  1 
ATOM   11681 C  C   . LEU E 1 69  ? 219.275 302.258 265.120 1.00 45.54  ? 69  LEU E C   1 
ATOM   11682 O  O   . LEU E 1 69  ? 218.296 302.357 265.865 1.00 47.66  ? 69  LEU E O   1 
ATOM   11683 C  CB  . LEU E 1 69  ? 219.437 304.458 263.962 1.00 48.27  ? 69  LEU E CB  1 
ATOM   11684 C  CG  . LEU E 1 69  ? 219.632 305.935 264.315 1.00 51.97  ? 69  LEU E CG  1 
ATOM   11685 C  CD1 . LEU E 1 69  ? 218.819 306.830 263.395 1.00 44.37  ? 69  LEU E CD1 1 
ATOM   11686 C  CD2 . LEU E 1 69  ? 219.270 306.192 265.770 1.00 48.80  ? 69  LEU E CD2 1 
ATOM   11687 N  N   . TRP E 1 70  ? 219.602 301.125 264.501 1.00 42.51  ? 70  TRP E N   1 
ATOM   11688 C  CA  . TRP E 1 70  ? 218.964 299.855 264.804 1.00 36.24  ? 70  TRP E CA  1 
ATOM   11689 C  C   . TRP E 1 70  ? 219.588 299.167 266.009 1.00 41.48  ? 70  TRP E C   1 
ATOM   11690 O  O   . TRP E 1 70  ? 219.049 298.158 266.474 1.00 46.37  ? 70  TRP E O   1 
ATOM   11691 C  CB  . TRP E 1 70  ? 219.036 298.933 263.584 1.00 34.93  ? 70  TRP E CB  1 
ATOM   11692 C  CG  . TRP E 1 70  ? 217.913 299.133 262.613 1.00 30.75  ? 70  TRP E CG  1 
ATOM   11693 C  CD1 . TRP E 1 70  ? 217.885 299.996 261.560 1.00 26.21  ? 70  TRP E CD1 1 
ATOM   11694 C  CD2 . TRP E 1 70  ? 216.658 298.446 262.603 1.00 28.71  ? 70  TRP E CD2 1 
ATOM   11695 N  NE1 . TRP E 1 70  ? 216.688 299.894 260.897 1.00 25.25  ? 70  TRP E NE1 1 
ATOM   11696 C  CE2 . TRP E 1 70  ? 215.916 298.948 261.517 1.00 26.33  ? 70  TRP E CE2 1 
ATOM   11697 C  CE3 . TRP E 1 70  ? 216.088 297.457 263.408 1.00 23.18  ? 70  TRP E CE3 1 
ATOM   11698 C  CZ2 . TRP E 1 70  ? 214.636 298.496 261.217 1.00 20.41  ? 70  TRP E CZ2 1 
ATOM   11699 C  CZ3 . TRP E 1 70  ? 214.818 297.010 263.108 1.00 22.43  ? 70  TRP E CZ3 1 
ATOM   11700 C  CH2 . TRP E 1 70  ? 214.106 297.528 262.022 1.00 20.13  ? 70  TRP E CH2 1 
ATOM   11701 N  N   . GLY E 1 71  ? 220.705 299.680 266.515 1.00 41.46  ? 71  GLY E N   1 
ATOM   11702 C  CA  . GLY E 1 71  ? 221.322 299.119 267.707 1.00 40.61  ? 71  GLY E CA  1 
ATOM   11703 C  C   . GLY E 1 71  ? 221.720 297.668 267.564 1.00 43.17  ? 71  GLY E C   1 
ATOM   11704 O  O   . GLY E 1 71  ? 221.594 296.893 268.520 1.00 48.43  ? 71  GLY E O   1 
ATOM   11705 N  N   . ILE E 1 72  ? 222.203 297.281 266.390 1.00 45.65  ? 72  ILE E N   1 
ATOM   11706 C  CA  . ILE E 1 72  ? 222.571 295.903 266.095 1.00 49.64  ? 72  ILE E CA  1 
ATOM   11707 C  C   . ILE E 1 72  ? 224.033 295.885 265.664 1.00 55.24  ? 72  ILE E C   1 
ATOM   11708 O  O   . ILE E 1 72  ? 224.377 296.453 264.624 1.00 57.20  ? 72  ILE E O   1 
ATOM   11709 C  CB  . ILE E 1 72  ? 221.673 295.289 265.008 1.00 44.95  ? 72  ILE E CB  1 
ATOM   11710 C  CG1 . ILE E 1 72  ? 220.253 295.100 265.545 1.00 39.92  ? 72  ILE E CG1 1 
ATOM   11711 C  CG2 . ILE E 1 72  ? 222.240 293.966 264.534 1.00 43.71  ? 72  ILE E CG2 1 
ATOM   11712 C  CD1 . ILE E 1 72  ? 219.170 295.408 264.540 1.00 37.49  ? 72  ILE E CD1 1 
ATOM   11713 N  N   . PRO E 1 73  ? 224.927 295.257 266.425 1.00 57.49  ? 73  PRO E N   1 
ATOM   11714 C  CA  . PRO E 1 73  ? 226.342 295.249 266.043 1.00 58.26  ? 73  PRO E CA  1 
ATOM   11715 C  C   . PRO E 1 73  ? 226.562 294.528 264.722 1.00 57.32  ? 73  PRO E C   1 
ATOM   11716 O  O   . PRO E 1 73  ? 225.859 293.574 264.382 1.00 57.51  ? 73  PRO E O   1 
ATOM   11717 C  CB  . PRO E 1 73  ? 227.021 294.513 267.204 1.00 55.34  ? 73  PRO E CB  1 
ATOM   11718 C  CG  . PRO E 1 73  ? 225.939 293.691 267.815 1.00 55.78  ? 73  PRO E CG  1 
ATOM   11719 C  CD  . PRO E 1 73  ? 224.676 294.484 267.652 1.00 54.33  ? 73  PRO E CD  1 
ATOM   11720 N  N   . ALA E 1 74  ? 227.555 295.001 263.975 1.00 60.55  ? 74  ALA E N   1 
ATOM   11721 C  CA  . ALA E 1 74  ? 227.885 294.415 262.684 1.00 60.99  ? 74  ALA E CA  1 
ATOM   11722 C  C   . ALA E 1 74  ? 228.722 293.156 262.872 1.00 59.89  ? 74  ALA E C   1 
ATOM   11723 O  O   . ALA E 1 74  ? 229.732 293.171 263.583 1.00 58.85  ? 74  ALA E O   1 
ATOM   11724 C  CB  . ALA E 1 74  ? 228.636 295.425 261.819 1.00 61.23  ? 74  ALA E CB  1 
ATOM   11725 N  N   . GLU E 1 75  ? 228.299 292.067 262.235 1.00 58.62  ? 75  GLU E N   1 
ATOM   11726 C  CA  . GLU E 1 75  ? 229.019 290.802 262.272 1.00 57.07  ? 75  GLU E CA  1 
ATOM   11727 C  C   . GLU E 1 75  ? 229.301 290.351 260.848 1.00 56.75  ? 75  GLU E C   1 
ATOM   11728 O  O   . GLU E 1 75  ? 228.383 290.278 260.025 1.00 60.13  ? 75  GLU E O   1 
ATOM   11729 C  CB  . GLU E 1 75  ? 228.227 289.726 263.022 1.00 51.96  ? 75  GLU E CB  1 
ATOM   11730 C  CG  . GLU E 1 75  ? 227.528 290.226 264.277 1.00 62.02  ? 75  GLU E CG  1 
ATOM   11731 C  CD  . GLU E 1 75  ? 228.470 290.352 265.462 1.00 68.26  ? 75  GLU E CD  1 
ATOM   11732 O  OE1 . GLU E 1 75  ? 229.438 289.566 265.543 1.00 64.12  ? 75  GLU E OE1 1 
ATOM   11733 O  OE2 . GLU E 1 75  ? 228.238 291.234 266.316 1.00 65.88  ? 75  GLU E OE2 1 
ATOM   11734 N  N   . SER E 1 76  ? 230.565 290.052 260.561 1.00 48.56  ? 76  SER E N   1 
ATOM   11735 C  CA  . SER E 1 76  ? 230.985 289.624 259.236 1.00 45.47  ? 76  SER E CA  1 
ATOM   11736 C  C   . SER E 1 76  ? 231.892 288.408 259.348 1.00 42.14  ? 76  SER E C   1 
ATOM   11737 O  O   . SER E 1 76  ? 232.594 288.224 260.345 1.00 46.77  ? 76  SER E O   1 
ATOM   11738 C  CB  . SER E 1 76  ? 231.707 290.750 258.487 1.00 46.53  ? 76  SER E CB  1 
ATOM   11739 O  OG  . SER E 1 76  ? 233.003 290.963 259.017 1.00 53.39  ? 76  SER E OG  1 
ATOM   11740 N  N   . ARG E 1 77  ? 231.867 287.580 258.310 1.00 37.03  ? 77  ARG E N   1 
ATOM   11741 C  CA  . ARG E 1 77  ? 232.673 286.365 258.284 1.00 34.04  ? 77  ARG E CA  1 
ATOM   11742 C  C   . ARG E 1 77  ? 232.919 285.908 256.851 1.00 28.14  ? 77  ARG E C   1 
ATOM   11743 O  O   . ARG E 1 77  ? 231.965 285.686 256.101 1.00 26.52  ? 77  ARG E O   1 
ATOM   11744 C  CB  . ARG E 1 77  ? 231.988 285.256 259.085 1.00 32.89  ? 77  ARG E CB  1 
ATOM   11745 C  CG  . ARG E 1 77  ? 232.663 283.904 258.971 1.00 30.56  ? 77  ARG E CG  1 
ATOM   11746 C  CD  . ARG E 1 77  ? 233.123 283.403 260.326 1.00 30.36  ? 77  ARG E CD  1 
ATOM   11747 N  NE  . ARG E 1 77  ? 234.066 282.299 260.204 1.00 33.21  ? 77  ARG E NE  1 
ATOM   11748 C  CZ  . ARG E 1 77  ? 233.784 281.036 260.495 1.00 32.62  ? 77  ARG E CZ  1 
ATOM   11749 N  NH1 . ARG E 1 77  ? 232.591 280.679 260.936 1.00 26.60  ? 77  ARG E NH1 1 
ATOM   11750 N  NH2 . ARG E 1 77  ? 234.726 280.110 260.344 1.00 32.61  ? 77  ARG E NH2 1 
ATOM   11751 N  N   . PRO E 1 78  ? 234.173 285.770 256.426 1.00 26.88  ? 78  PRO E N   1 
ATOM   11752 C  CA  . PRO E 1 78  ? 234.438 285.250 255.079 1.00 25.37  ? 78  PRO E CA  1 
ATOM   11753 C  C   . PRO E 1 78  ? 234.329 283.733 255.033 1.00 26.35  ? 78  PRO E C   1 
ATOM   11754 O  O   . PRO E 1 78  ? 234.783 283.028 255.938 1.00 31.52  ? 78  PRO E O   1 
ATOM   11755 C  CB  . PRO E 1 78  ? 235.869 285.719 254.794 1.00 24.78  ? 78  PRO E CB  1 
ATOM   11756 C  CG  . PRO E 1 78  ? 236.493 285.883 256.131 1.00 26.76  ? 78  PRO E CG  1 
ATOM   11757 C  CD  . PRO E 1 78  ? 235.404 286.175 257.126 1.00 27.59  ? 78  PRO E CD  1 
ATOM   11758 N  N   . ILE E 1 79  ? 233.712 283.232 253.961 1.00 24.25  ? 79  ILE E N   1 
ATOM   11759 C  CA  . ILE E 1 79  ? 233.455 281.808 253.782 1.00 22.45  ? 79  ILE E CA  1 
ATOM   11760 C  C   . ILE E 1 79  ? 233.598 281.457 252.305 1.00 19.52  ? 79  ILE E C   1 
ATOM   11761 O  O   . ILE E 1 79  ? 233.663 282.328 251.435 1.00 20.80  ? 79  ILE E O   1 
ATOM   11762 C  CB  . ILE E 1 79  ? 232.057 281.395 254.296 1.00 21.63  ? 79  ILE E CB  1 
ATOM   11763 C  CG1 . ILE E 1 79  ? 230.957 282.087 253.489 1.00 19.18  ? 79  ILE E CG1 1 
ATOM   11764 C  CG2 . ILE E 1 79  ? 231.909 281.718 255.771 1.00 19.97  ? 79  ILE E CG2 1 
ATOM   11765 C  CD1 . ILE E 1 79  ? 230.381 281.241 252.383 1.00 17.24  ? 79  ILE E CD1 1 
ATOM   11766 N  N   . SER E 1 80  ? 233.646 280.152 252.035 1.00 19.36  ? 80  SER E N   1 
ATOM   11767 C  CA  . SER E 1 80  ? 233.707 279.610 250.685 1.00 18.02  ? 80  SER E CA  1 
ATOM   11768 C  C   . SER E 1 80  ? 232.642 278.537 250.518 1.00 18.05  ? 80  SER E C   1 
ATOM   11769 O  O   . SER E 1 80  ? 232.343 277.798 251.459 1.00 22.52  ? 80  SER E O   1 
ATOM   11770 C  CB  . SER E 1 80  ? 235.089 279.017 250.377 1.00 20.21  ? 80  SER E CB  1 
ATOM   11771 O  OG  . SER E 1 80  ? 236.041 280.036 250.146 1.00 23.35  ? 80  SER E OG  1 
ATOM   11772 N  N   . VAL E 1 81  ? 232.074 278.453 249.314 1.00 17.77  ? 81  VAL E N   1 
ATOM   11773 C  CA  . VAL E 1 81  ? 231.062 277.455 248.995 1.00 19.99  ? 81  VAL E CA  1 
ATOM   11774 C  C   . VAL E 1 81  ? 231.357 276.855 247.627 1.00 22.64  ? 81  VAL E C   1 
ATOM   11775 O  O   . VAL E 1 81  ? 232.049 277.445 246.793 1.00 26.09  ? 81  VAL E O   1 
ATOM   11776 C  CB  . VAL E 1 81  ? 229.632 278.037 249.021 1.00 22.86  ? 81  VAL E CB  1 
ATOM   11777 C  CG1 . VAL E 1 81  ? 229.255 278.463 250.431 1.00 20.66  ? 81  VAL E CG1 1 
ATOM   11778 C  CG2 . VAL E 1 81  ? 229.516 279.198 248.050 1.00 17.51  ? 81  VAL E CG2 1 
ATOM   11779 N  N   . ASP E 1 82  ? 230.806 275.666 247.402 1.00 20.89  ? 82  ASP E N   1 
ATOM   11780 C  CA  . ASP E 1 82  ? 230.949 274.967 246.136 1.00 23.32  ? 82  ASP E CA  1 
ATOM   11781 C  C   . ASP E 1 82  ? 229.775 275.283 245.212 1.00 24.07  ? 82  ASP E C   1 
ATOM   11782 O  O   . ASP E 1 82  ? 228.773 275.876 245.613 1.00 29.44  ? 82  ASP E O   1 
ATOM   11783 C  CB  . ASP E 1 82  ? 231.059 273.461 246.370 1.00 23.74  ? 82  ASP E CB  1 
ATOM   11784 C  CG  . ASP E 1 82  ? 232.137 272.820 245.521 1.00 34.27  ? 82  ASP E CG  1 
ATOM   11785 O  OD1 . ASP E 1 82  ? 232.177 273.091 244.305 1.00 36.80  ? 82  ASP E OD1 1 
ATOM   11786 O  OD2 . ASP E 1 82  ? 232.952 272.050 246.071 1.00 43.12  ? 82  ASP E OD2 1 
ATOM   11787 N  N   . ALA E 1 83  ? 229.915 274.879 243.953 1.00 23.63  ? 83  ALA E N   1 
ATOM   11788 C  CA  . ALA E 1 83  ? 228.891 275.153 242.956 1.00 24.59  ? 83  ALA E CA  1 
ATOM   11789 C  C   . ALA E 1 83  ? 227.618 274.370 243.255 1.00 23.37  ? 83  ALA E C   1 
ATOM   11790 O  O   . ALA E 1 83  ? 227.653 273.274 243.819 1.00 28.42  ? 83  ALA E O   1 
ATOM   11791 C  CB  . ALA E 1 83  ? 229.405 274.806 241.560 1.00 23.31  ? 83  ALA E CB  1 
ATOM   11792 N  N   . PHE E 1 84  ? 226.480 274.950 242.877 1.00 21.39  ? 84  PHE E N   1 
ATOM   11793 C  CA  . PHE E 1 84  ? 225.207 274.263 243.058 1.00 23.08  ? 84  PHE E CA  1 
ATOM   11794 C  C   . PHE E 1 84  ? 224.189 274.816 242.073 1.00 22.08  ? 84  PHE E C   1 
ATOM   11795 O  O   . PHE E 1 84  ? 224.327 275.930 241.573 1.00 25.14  ? 84  PHE E O   1 
ATOM   11796 C  CB  . PHE E 1 84  ? 224.690 274.396 244.499 1.00 22.63  ? 84  PHE E CB  1 
ATOM   11797 C  CG  . PHE E 1 84  ? 224.628 275.815 245.005 1.00 20.64  ? 84  PHE E CG  1 
ATOM   11798 C  CD1 . PHE E 1 84  ? 225.749 276.424 245.542 1.00 20.29  ? 84  PHE E CD1 1 
ATOM   11799 C  CD2 . PHE E 1 84  ? 223.445 276.532 244.953 1.00 19.61  ? 84  PHE E CD2 1 
ATOM   11800 C  CE1 . PHE E 1 84  ? 225.693 277.723 246.012 1.00 17.73  ? 84  PHE E CE1 1 
ATOM   11801 C  CE2 . PHE E 1 84  ? 223.384 277.832 245.420 1.00 15.93  ? 84  PHE E CE2 1 
ATOM   11802 C  CZ  . PHE E 1 84  ? 224.510 278.427 245.951 1.00 17.51  ? 84  PHE E CZ  1 
ATOM   11803 N  N   . TRP E 1 85  ? 223.158 274.024 241.805 1.00 23.28  ? 85  TRP E N   1 
ATOM   11804 C  CA  . TRP E 1 85  ? 222.018 274.484 241.028 1.00 23.50  ? 85  TRP E CA  1 
ATOM   11805 C  C   . TRP E 1 85  ? 221.029 275.176 241.954 1.00 20.73  ? 85  TRP E C   1 
ATOM   11806 O  O   . TRP E 1 85  ? 220.760 274.695 243.056 1.00 22.43  ? 85  TRP E O   1 
ATOM   11807 C  CB  . TRP E 1 85  ? 221.330 273.316 240.323 1.00 27.21  ? 85  TRP E CB  1 
ATOM   11808 C  CG  . TRP E 1 85  ? 222.221 272.535 239.420 1.00 32.47  ? 85  TRP E CG  1 
ATOM   11809 C  CD1 . TRP E 1 85  ? 222.910 271.401 239.732 1.00 35.52  ? 85  TRP E CD1 1 
ATOM   11810 C  CD2 . TRP E 1 85  ? 222.509 272.814 238.047 1.00 35.71  ? 85  TRP E CD2 1 
ATOM   11811 N  NE1 . TRP E 1 85  ? 223.616 270.961 238.641 1.00 38.83  ? 85  TRP E NE1 1 
ATOM   11812 C  CE2 . TRP E 1 85  ? 223.386 271.811 237.593 1.00 39.84  ? 85  TRP E CE2 1 
ATOM   11813 C  CE3 . TRP E 1 85  ? 222.111 273.816 237.158 1.00 35.43  ? 85  TRP E CE3 1 
ATOM   11814 C  CZ2 . TRP E 1 85  ? 223.873 271.782 236.291 1.00 41.77  ? 85  TRP E CZ2 1 
ATOM   11815 C  CZ3 . TRP E 1 85  ? 222.595 273.786 235.868 1.00 39.75  ? 85  TRP E CZ3 1 
ATOM   11816 C  CH2 . TRP E 1 85  ? 223.467 272.775 235.445 1.00 42.13  ? 85  TRP E CH2 1 
ATOM   11817 N  N   . MET E 1 86  ? 220.487 276.302 241.500 1.00 19.25  ? 86  MET E N   1 
ATOM   11818 C  CA  . MET E 1 86  ? 219.499 277.050 242.262 1.00 19.69  ? 86  MET E CA  1 
ATOM   11819 C  C   . MET E 1 86  ? 218.318 277.408 241.375 1.00 21.05  ? 86  MET E C   1 
ATOM   11820 O  O   . MET E 1 86  ? 218.493 277.775 240.211 1.00 26.15  ? 86  MET E O   1 
ATOM   11821 C  CB  . MET E 1 86  ? 220.098 278.326 242.864 1.00 18.39  ? 86  MET E CB  1 
ATOM   11822 C  CG  . MET E 1 86  ? 219.252 278.928 243.974 1.00 15.60  ? 86  MET E CG  1 
ATOM   11823 S  SD  . MET E 1 86  ? 219.897 280.476 244.623 1.00 29.60  ? 86  MET E SD  1 
ATOM   11824 C  CE  . MET E 1 86  ? 220.162 280.033 246.335 1.00 14.86  ? 86  MET E CE  1 
ATOM   11825 N  N   . ASP E 1 87  ? 217.116 277.309 241.939 1.00 18.70  ? 87  ASP E N   1 
ATOM   11826 C  CA  . ASP E 1 87  ? 215.910 277.680 241.210 1.00 17.94  ? 87  ASP E CA  1 
ATOM   11827 C  C   . ASP E 1 87  ? 215.993 279.125 240.738 1.00 19.70  ? 87  ASP E C   1 
ATOM   11828 O  O   . ASP E 1 87  ? 216.373 280.020 241.497 1.00 21.56  ? 87  ASP E O   1 
ATOM   11829 C  CB  . ASP E 1 87  ? 214.678 277.487 242.093 1.00 16.43  ? 87  ASP E CB  1 
ATOM   11830 C  CG  . ASP E 1 87  ? 214.115 276.087 242.011 1.00 22.39  ? 87  ASP E CG  1 
ATOM   11831 O  OD1 . ASP E 1 87  ? 214.109 275.512 240.905 1.00 25.38  ? 87  ASP E OD1 1 
ATOM   11832 O  OD2 . ASP E 1 87  ? 213.677 275.562 243.054 1.00 24.00  ? 87  ASP E OD2 1 
ATOM   11833 N  N   . ARG E 1 88  ? 215.620 279.351 239.476 1.00 19.93  ? 88  ARG E N   1 
ATOM   11834 C  CA  . ARG E 1 88  ? 215.652 280.700 238.922 1.00 16.82  ? 88  ARG E CA  1 
ATOM   11835 C  C   . ARG E 1 88  ? 214.723 281.634 239.687 1.00 15.33  ? 88  ARG E C   1 
ATOM   11836 O  O   . ARG E 1 88  ? 215.072 282.790 239.951 1.00 15.87  ? 88  ARG E O   1 
ATOM   11837 C  CB  . ARG E 1 88  ? 215.272 280.664 237.443 1.00 24.60  ? 88  ARG E CB  1 
ATOM   11838 C  CG  . ARG E 1 88  ? 216.096 281.578 236.561 1.00 32.99  ? 88  ARG E CG  1 
ATOM   11839 C  CD  . ARG E 1 88  ? 215.673 281.449 235.110 1.00 38.93  ? 88  ARG E CD  1 
ATOM   11840 N  NE  . ARG E 1 88  ? 215.431 280.059 234.744 1.00 41.48  ? 88  ARG E NE  1 
ATOM   11841 C  CZ  . ARG E 1 88  ? 216.179 279.367 233.897 1.00 49.27  ? 88  ARG E CZ  1 
ATOM   11842 N  NH1 . ARG E 1 88  ? 217.232 279.905 233.307 1.00 49.51  ? 88  ARG E NH1 1 
ATOM   11843 N  NH2 . ARG E 1 88  ? 215.864 278.100 233.640 1.00 44.86  ? 88  ARG E NH2 1 
ATOM   11844 N  N   . THR E 1 89  ? 213.533 281.156 240.041 1.00 15.26  ? 89  THR E N   1 
ATOM   11845 C  CA  . THR E 1 89  ? 212.548 281.942 240.767 1.00 12.13  ? 89  THR E CA  1 
ATOM   11846 C  C   . THR E 1 89  ? 212.113 281.187 242.016 1.00 16.94  ? 89  THR E C   1 
ATOM   11847 O  O   . THR E 1 89  ? 212.490 280.034 242.239 1.00 20.27  ? 89  THR E O   1 
ATOM   11848 C  CB  . THR E 1 89  ? 211.324 282.261 239.895 1.00 16.69  ? 89  THR E CB  1 
ATOM   11849 O  OG1 . THR E 1 89  ? 210.476 281.110 239.814 1.00 22.08  ? 89  THR E OG1 1 
ATOM   11850 C  CG2 . THR E 1 89  ? 211.753 282.667 238.497 1.00 16.16  ? 89  THR E CG2 1 
ATOM   11851 N  N   . GLU E 1 90  ? 211.318 281.859 242.843 1.00 19.41  ? 90  GLU E N   1 
ATOM   11852 C  CA  . GLU E 1 90  ? 210.711 281.200 243.987 1.00 15.67  ? 90  GLU E CA  1 
ATOM   11853 C  C   . GLU E 1 90  ? 209.647 280.213 243.519 1.00 17.17  ? 90  GLU E C   1 
ATOM   11854 O  O   . GLU E 1 90  ? 209.086 280.342 242.429 1.00 20.72  ? 90  GLU E O   1 
ATOM   11855 C  CB  . GLU E 1 90  ? 210.091 282.229 244.934 1.00 13.39  ? 90  GLU E CB  1 
ATOM   11856 C  CG  . GLU E 1 90  ? 211.006 283.389 245.300 1.00 15.84  ? 90  GLU E CG  1 
ATOM   11857 C  CD  . GLU E 1 90  ? 210.316 284.739 245.202 1.00 15.78  ? 90  GLU E CD  1 
ATOM   11858 O  OE1 . GLU E 1 90  ? 209.437 284.905 244.333 1.00 17.82  ? 90  GLU E OE1 1 
ATOM   11859 O  OE2 . GLU E 1 90  ? 210.652 285.636 246.001 1.00 15.66  ? 90  GLU E OE2 1 
ATOM   11860 N  N   . ILE E 1 91  ? 209.376 279.212 244.357 1.00 17.85  ? 91  ILE E N   1 
ATOM   11861 C  CA  . ILE E 1 91  ? 208.337 278.242 244.039 1.00 14.50  ? 91  ILE E CA  1 
ATOM   11862 C  C   . ILE E 1 91  ? 207.004 278.963 243.900 1.00 15.17  ? 91  ILE E C   1 
ATOM   11863 O  O   . ILE E 1 91  ? 206.630 279.781 244.748 1.00 20.99  ? 91  ILE E O   1 
ATOM   11864 C  CB  . ILE E 1 91  ? 208.283 277.147 245.115 1.00 15.95  ? 91  ILE E CB  1 
ATOM   11865 C  CG1 . ILE E 1 91  ? 209.613 276.391 245.174 1.00 13.30  ? 91  ILE E CG1 1 
ATOM   11866 C  CG2 . ILE E 1 91  ? 207.123 276.193 244.863 1.00 14.35  ? 91  ILE E CG2 1 
ATOM   11867 C  CD1 . ILE E 1 91  ? 209.993 275.721 243.880 1.00 13.07  ? 91  ILE E CD1 1 
ATOM   11868 N  N   . THR E 1 92  ? 206.281 278.665 242.824 1.00 15.16  ? 92  THR E N   1 
ATOM   11869 C  CA  . THR E 1 92  ? 205.016 279.317 242.531 1.00 15.09  ? 92  THR E CA  1 
ATOM   11870 C  C   . THR E 1 92  ? 203.851 278.486 243.066 1.00 15.00  ? 92  THR E C   1 
ATOM   11871 O  O   . THR E 1 92  ? 204.023 277.387 243.598 1.00 16.56  ? 92  THR E O   1 
ATOM   11872 C  CB  . THR E 1 92  ? 204.864 279.565 241.028 1.00 14.51  ? 92  THR E CB  1 
ATOM   11873 O  OG1 . THR E 1 92  ? 204.863 278.317 240.328 1.00 18.71  ? 92  THR E OG1 1 
ATOM   11874 C  CG2 . THR E 1 92  ? 206.003 280.423 240.513 1.00 12.88  ? 92  THR E CG2 1 
ATOM   11875 N  N   . ASN E 1 93  ? 202.643 279.037 242.932 1.00 17.88  ? 93  ASN E N   1 
ATOM   11876 C  CA  . ASN E 1 93  ? 201.451 278.334 243.393 1.00 16.95  ? 93  ASN E CA  1 
ATOM   11877 C  C   . ASN E 1 93  ? 201.212 277.061 242.591 1.00 15.33  ? 93  ASN E C   1 
ATOM   11878 O  O   . ASN E 1 93  ? 200.784 276.043 243.145 1.00 20.54  ? 93  ASN E O   1 
ATOM   11879 C  CB  . ASN E 1 93  ? 200.232 279.255 243.313 1.00 18.93  ? 93  ASN E CB  1 
ATOM   11880 C  CG  . ASN E 1 93  ? 200.210 280.294 244.419 1.00 15.29  ? 93  ASN E CG  1 
ATOM   11881 O  OD1 . ASN E 1 93  ? 200.362 279.969 245.595 1.00 15.85  ? 93  ASN E OD1 1 
ATOM   11882 N  ND2 . ASN E 1 93  ? 200.003 281.550 244.047 1.00 17.64  ? 93  ASN E ND2 1 
ATOM   11883 N  N   . ALA E 1 94  ? 201.470 277.101 241.283 1.00 15.41  ? 94  ALA E N   1 
ATOM   11884 C  CA  . ALA E 1 94  ? 201.260 275.923 240.447 1.00 16.10  ? 94  ALA E CA  1 
ATOM   11885 C  C   . ALA E 1 94  ? 202.272 274.826 240.759 1.00 19.55  ? 94  ALA E C   1 
ATOM   11886 O  O   . ALA E 1 94  ? 201.925 273.638 240.792 1.00 25.97  ? 94  ALA E O   1 
ATOM   11887 C  CB  . ALA E 1 94  ? 201.325 276.316 238.972 1.00 13.65  ? 94  ALA E CB  1 
ATOM   11888 N  N   . GLN E 1 95  ? 203.530 275.203 240.992 1.00 13.79  ? 95  GLN E N   1 
ATOM   11889 C  CA  . GLN E 1 95  ? 204.558 274.209 241.280 1.00 13.98  ? 95  GLN E CA  1 
ATOM   11890 C  C   . GLN E 1 95  ? 204.259 273.463 242.576 1.00 18.62  ? 95  GLN E C   1 
ATOM   11891 O  O   . GLN E 1 95  ? 204.489 272.252 242.669 1.00 25.73  ? 95  GLN E O   1 
ATOM   11892 C  CB  . GLN E 1 95  ? 205.930 274.880 241.334 1.00 14.74  ? 95  GLN E CB  1 
ATOM   11893 C  CG  . GLN E 1 95  ? 206.445 275.318 239.968 1.00 13.32  ? 95  GLN E CG  1 
ATOM   11894 C  CD  . GLN E 1 95  ? 207.495 276.407 240.049 1.00 15.57  ? 95  GLN E CD  1 
ATOM   11895 O  OE1 . GLN E 1 95  ? 207.905 276.812 241.134 1.00 20.48  ? 95  GLN E OE1 1 
ATOM   11896 N  NE2 . GLN E 1 95  ? 207.934 276.889 238.893 1.00 13.30  ? 95  GLN E NE2 1 
ATOM   11897 N  N   . TYR E 1 96  ? 203.758 274.168 243.591 1.00 16.64  ? 96  TYR E N   1 
ATOM   11898 C  CA  . TYR E 1 96  ? 203.358 273.511 244.831 1.00 15.59  ? 96  TYR E CA  1 
ATOM   11899 C  C   . TYR E 1 96  ? 202.036 272.768 244.682 1.00 17.59  ? 96  TYR E C   1 
ATOM   11900 O  O   . TYR E 1 96  ? 201.820 271.741 245.342 1.00 22.98  ? 96  TYR E O   1 
ATOM   11901 C  CB  . TYR E 1 96  ? 203.265 274.537 245.961 1.00 14.33  ? 96  TYR E CB  1 
ATOM   11902 C  CG  . TYR E 1 96  ? 203.310 273.921 247.337 1.00 15.80  ? 96  TYR E CG  1 
ATOM   11903 C  CD1 . TYR E 1 96  ? 204.520 273.678 247.969 1.00 12.74  ? 96  TYR E CD1 1 
ATOM   11904 C  CD2 . TYR E 1 96  ? 202.142 273.581 248.005 1.00 14.14  ? 96  TYR E CD2 1 
ATOM   11905 C  CE1 . TYR E 1 96  ? 204.567 273.111 249.224 1.00 12.87  ? 96  TYR E CE1 1 
ATOM   11906 C  CE2 . TYR E 1 96  ? 202.180 273.013 249.260 1.00 15.89  ? 96  TYR E CE2 1 
ATOM   11907 C  CZ  . TYR E 1 96  ? 203.395 272.783 249.866 1.00 17.01  ? 96  TYR E CZ  1 
ATOM   11908 O  OH  . TYR E 1 96  ? 203.440 272.218 251.117 1.00 22.46  ? 96  TYR E OH  1 
ATOM   11909 N  N   . ARG E 1 97  ? 201.136 273.273 243.837 1.00 18.55  ? 97  ARG E N   1 
ATOM   11910 C  CA  . ARG E 1 97  ? 199.904 272.548 243.564 1.00 18.53  ? 97  ARG E CA  1 
ATOM   11911 C  C   . ARG E 1 97  ? 200.190 271.209 242.906 1.00 20.70  ? 97  ARG E C   1 
ATOM   11912 O  O   . ARG E 1 97  ? 199.417 270.266 243.067 1.00 22.52  ? 97  ARG E O   1 
ATOM   11913 C  CB  . ARG E 1 97  ? 198.978 273.389 242.688 1.00 18.95  ? 97  ARG E CB  1 
ATOM   11914 C  CG  . ARG E 1 97  ? 197.511 273.047 242.849 1.00 16.76  ? 97  ARG E CG  1 
ATOM   11915 C  CD  . ARG E 1 97  ? 196.636 273.951 242.004 1.00 24.49  ? 97  ARG E CD  1 
ATOM   11916 N  NE  . ARG E 1 97  ? 196.601 275.314 242.520 1.00 23.87  ? 97  ARG E NE  1 
ATOM   11917 C  CZ  . ARG E 1 97  ? 197.089 276.365 241.878 1.00 20.39  ? 97  ARG E CZ  1 
ATOM   11918 N  NH1 . ARG E 1 97  ? 197.651 276.247 240.687 1.00 20.94  ? 97  ARG E NH1 1 
ATOM   11919 N  NH2 . ARG E 1 97  ? 197.011 277.565 242.443 1.00 24.09  ? 97  ARG E NH2 1 
ATOM   11920 N  N   . GLN E 1 98  ? 201.289 271.108 242.158 1.00 19.17  ? 98  GLN E N   1 
ATOM   11921 C  CA  . GLN E 1 98  ? 201.689 269.808 241.624 1.00 19.23  ? 98  GLN E CA  1 
ATOM   11922 C  C   . GLN E 1 98  ? 201.961 268.811 242.747 1.00 20.79  ? 98  GLN E C   1 
ATOM   11923 O  O   . GLN E 1 98  ? 201.517 267.658 242.691 1.00 24.11  ? 98  GLN E O   1 
ATOM   11924 C  CB  . GLN E 1 98  ? 202.920 269.965 240.733 1.00 19.87  ? 98  GLN E CB  1 
ATOM   11925 C  CG  . GLN E 1 98  ? 202.986 268.972 239.594 1.00 22.17  ? 98  GLN E CG  1 
ATOM   11926 C  CD  . GLN E 1 98  ? 204.385 268.816 239.042 1.00 32.34  ? 98  GLN E CD  1 
ATOM   11927 O  OE1 . GLN E 1 98  ? 205.090 269.800 238.823 1.00 44.01  ? 98  GLN E OE1 1 
ATOM   11928 N  NE2 . GLN E 1 98  ? 204.797 267.576 238.814 1.00 34.80  ? 98  GLN E NE2 1 
ATOM   11929 N  N   . PHE E 1 99  ? 202.687 269.243 243.779 1.00 19.28  ? 99  PHE E N   1 
ATOM   11930 C  CA  . PHE E 1 99  ? 202.933 268.401 244.947 1.00 15.25  ? 99  PHE E CA  1 
ATOM   11931 C  C   . PHE E 1 99  ? 201.627 268.023 245.639 1.00 19.50  ? 99  PHE E C   1 
ATOM   11932 O  O   . PHE E 1 99  ? 201.403 266.856 245.996 1.00 26.70  ? 99  PHE E O   1 
ATOM   11933 C  CB  . PHE E 1 99  ? 203.863 269.148 245.903 1.00 18.06  ? 99  PHE E CB  1 
ATOM   11934 C  CG  . PHE E 1 99  ? 204.178 268.408 247.166 1.00 19.81  ? 99  PHE E CG  1 
ATOM   11935 C  CD1 . PHE E 1 99  ? 204.347 267.038 247.167 1.00 17.80  ? 99  PHE E CD1 1 
ATOM   11936 C  CD2 . PHE E 1 99  ? 204.322 269.097 248.357 1.00 15.46  ? 99  PHE E CD2 1 
ATOM   11937 C  CE1 . PHE E 1 99  ? 204.647 266.369 248.333 1.00 17.69  ? 99  PHE E CE1 1 
ATOM   11938 C  CE2 . PHE E 1 99  ? 204.622 268.434 249.522 1.00 16.25  ? 99  PHE E CE2 1 
ATOM   11939 C  CZ  . PHE E 1 99  ? 204.785 267.068 249.511 1.00 16.46  ? 99  PHE E CZ  1 
ATOM   11940 N  N   . VAL E 1 100 ? 200.751 269.008 245.834 1.00 18.78  ? 100 VAL E N   1 
ATOM   11941 C  CA  . VAL E 1 100 ? 199.479 268.748 246.505 1.00 19.65  ? 100 VAL E CA  1 
ATOM   11942 C  C   . VAL E 1 100 ? 198.651 267.746 245.708 1.00 22.27  ? 100 VAL E C   1 
ATOM   11943 O  O   . VAL E 1 100 ? 198.030 266.837 246.274 1.00 27.30  ? 100 VAL E O   1 
ATOM   11944 C  CB  . VAL E 1 100 ? 198.716 270.066 246.731 1.00 20.96  ? 100 VAL E CB  1 
ATOM   11945 C  CG1 . VAL E 1 100 ? 197.295 269.783 247.179 1.00 21.95  ? 100 VAL E CG1 1 
ATOM   11946 C  CG2 . VAL E 1 100 ? 199.441 270.929 247.751 1.00 18.59  ? 100 VAL E CG2 1 
ATOM   11947 N  N   . TYR E 1 101 ? 198.624 267.899 244.384 1.00 21.93  ? 101 TYR E N   1 
ATOM   11948 C  CA  . TYR E 1 101 ? 197.837 267.011 243.539 1.00 20.33  ? 101 TYR E CA  1 
ATOM   11949 C  C   . TYR E 1 101 ? 198.426 265.609 243.512 1.00 27.10  ? 101 TYR E C   1 
ATOM   11950 O  O   . TYR E 1 101 ? 197.685 264.624 243.452 1.00 35.80  ? 101 TYR E O   1 
ATOM   11951 C  CB  . TYR E 1 101 ? 197.740 267.583 242.127 1.00 21.48  ? 101 TYR E CB  1 
ATOM   11952 C  CG  . TYR E 1 101 ? 196.714 268.681 241.982 1.00 25.41  ? 101 TYR E CG  1 
ATOM   11953 C  CD1 . TYR E 1 101 ? 195.938 269.080 243.062 1.00 25.41  ? 101 TYR E CD1 1 
ATOM   11954 C  CD2 . TYR E 1 101 ? 196.525 269.323 240.769 1.00 20.87  ? 101 TYR E CD2 1 
ATOM   11955 C  CE1 . TYR E 1 101 ? 195.003 270.083 242.935 1.00 22.64  ? 101 TYR E CE1 1 
ATOM   11956 C  CE2 . TYR E 1 101 ? 195.590 270.327 240.632 1.00 23.56  ? 101 TYR E CE2 1 
ATOM   11957 C  CZ  . TYR E 1 101 ? 194.831 270.703 241.719 1.00 27.48  ? 101 TYR E CZ  1 
ATOM   11958 O  OH  . TYR E 1 101 ? 193.897 271.705 241.591 1.00 36.49  ? 101 TYR E OH  1 
ATOM   11959 N  N   . TYR E 1 102 ? 199.755 265.492 243.550 1.00 24.27  ? 102 TYR E N   1 
ATOM   11960 C  CA  . TYR E 1 102 ? 200.352 264.166 243.669 1.00 22.91  ? 102 TYR E CA  1 
ATOM   11961 C  C   . TYR E 1 102 ? 199.920 263.493 244.963 1.00 25.72  ? 102 TYR E C   1 
ATOM   11962 O  O   . TYR E 1 102 ? 199.577 262.305 244.973 1.00 32.58  ? 102 TYR E O   1 
ATOM   11963 C  CB  . TYR E 1 102 ? 201.877 264.243 243.597 1.00 20.50  ? 102 TYR E CB  1 
ATOM   11964 C  CG  . TYR E 1 102 ? 202.541 262.938 243.985 1.00 25.05  ? 102 TYR E CG  1 
ATOM   11965 C  CD1 . TYR E 1 102 ? 202.839 262.655 245.313 1.00 28.40  ? 102 TYR E CD1 1 
ATOM   11966 C  CD2 . TYR E 1 102 ? 202.847 261.981 243.030 1.00 23.73  ? 102 TYR E CD2 1 
ATOM   11967 C  CE1 . TYR E 1 102 ? 203.430 261.464 245.674 1.00 26.79  ? 102 TYR E CE1 1 
ATOM   11968 C  CE2 . TYR E 1 102 ? 203.442 260.785 243.384 1.00 27.66  ? 102 TYR E CE2 1 
ATOM   11969 C  CZ  . TYR E 1 102 ? 203.731 260.533 244.707 1.00 32.94  ? 102 TYR E CZ  1 
ATOM   11970 O  OH  . TYR E 1 102 ? 204.322 259.345 245.065 1.00 42.55  ? 102 TYR E OH  1 
ATOM   11971 N  N   . VAL E 1 103 ? 199.950 264.232 246.074 1.00 23.34  ? 103 VAL E N   1 
ATOM   11972 C  CA  . VAL E 1 103 ? 199.533 263.641 247.346 1.00 26.04  ? 103 VAL E CA  1 
ATOM   11973 C  C   . VAL E 1 103 ? 198.073 263.212 247.275 1.00 26.98  ? 103 VAL E C   1 
ATOM   11974 O  O   . VAL E 1 103 ? 197.702 262.120 247.730 1.00 30.43  ? 103 VAL E O   1 
ATOM   11975 C  CB  . VAL E 1 103 ? 199.783 264.623 248.507 1.00 26.74  ? 103 VAL E CB  1 
ATOM   11976 C  CG1 . VAL E 1 103 ? 198.853 264.322 249.668 1.00 26.14  ? 103 VAL E CG1 1 
ATOM   11977 C  CG2 . VAL E 1 103 ? 201.230 264.551 248.958 1.00 21.52  ? 103 VAL E CG2 1 
ATOM   11978 N  N   . ARG E 1 104 ? 197.223 264.062 246.696 1.00 31.27  ? 104 ARG E N   1 
ATOM   11979 C  CA  . ARG E 1 104 ? 195.807 263.735 246.567 1.00 28.62  ? 104 ARG E CA  1 
ATOM   11980 C  C   . ARG E 1 104 ? 195.607 262.470 245.741 1.00 30.92  ? 104 ARG E C   1 
ATOM   11981 O  O   . ARG E 1 104 ? 194.845 261.576 246.126 1.00 35.80  ? 104 ARG E O   1 
ATOM   11982 C  CB  . ARG E 1 104 ? 195.062 264.913 245.940 1.00 26.38  ? 104 ARG E CB  1 
ATOM   11983 C  CG  . ARG E 1 104 ? 193.627 264.620 245.546 1.00 33.16  ? 104 ARG E CG  1 
ATOM   11984 C  CD  . ARG E 1 104 ? 193.162 265.565 244.451 1.00 30.83  ? 104 ARG E CD  1 
ATOM   11985 N  NE  . ARG E 1 104 ? 193.889 265.349 243.206 1.00 30.62  ? 104 ARG E NE  1 
ATOM   11986 C  CZ  . ARG E 1 104 ? 193.834 266.153 242.154 1.00 29.02  ? 104 ARG E CZ  1 
ATOM   11987 N  NH1 . ARG E 1 104 ? 193.086 267.244 242.156 1.00 30.01  ? 104 ARG E NH1 1 
ATOM   11988 N  NH2 . ARG E 1 104 ? 194.548 265.857 241.073 1.00 23.48  ? 104 ARG E NH2 1 
ATOM   11989 N  N   . ASP E 1 105 ? 196.289 262.377 244.597 1.00 31.08  ? 105 ASP E N   1 
ATOM   11990 C  CA  . ASP E 1 105 ? 196.133 261.214 243.730 1.00 33.74  ? 105 ASP E CA  1 
ATOM   11991 C  C   . ASP E 1 105 ? 196.639 259.946 244.404 1.00 34.18  ? 105 ASP E C   1 
ATOM   11992 O  O   . ASP E 1 105 ? 196.007 258.889 244.300 1.00 41.66  ? 105 ASP E O   1 
ATOM   11993 C  CB  . ASP E 1 105 ? 196.860 261.445 242.406 1.00 34.63  ? 105 ASP E CB  1 
ATOM   11994 C  CG  . ASP E 1 105 ? 196.218 262.534 241.575 1.00 43.10  ? 105 ASP E CG  1 
ATOM   11995 O  OD1 . ASP E 1 105 ? 195.061 262.901 241.868 1.00 43.97  ? 105 ASP E OD1 1 
ATOM   11996 O  OD2 . ASP E 1 105 ? 196.870 263.028 240.632 1.00 43.64  ? 105 ASP E OD2 1 
ATOM   11997 N  N   . SER E 1 106 ? 197.777 260.025 245.097 1.00 34.83  ? 106 SER E N   1 
ATOM   11998 C  CA  . SER E 1 106 ? 198.291 258.845 245.780 1.00 34.22  ? 106 SER E CA  1 
ATOM   11999 C  C   . SER E 1 106 ? 197.331 258.374 246.864 1.00 34.22  ? 106 SER E C   1 
ATOM   12000 O  O   . SER E 1 106 ? 197.079 257.171 246.998 1.00 39.44  ? 106 SER E O   1 
ATOM   12001 C  CB  . SER E 1 106 ? 199.666 259.126 246.381 1.00 33.86  ? 106 SER E CB  1 
ATOM   12002 O  OG  . SER E 1 106 ? 199.851 258.319 247.529 1.00 39.70  ? 106 SER E OG  1 
ATOM   12003 N  N   . ILE E 1 107 ? 196.779 259.303 247.647 1.00 32.35  ? 107 ILE E N   1 
ATOM   12004 C  CA  . ILE E 1 107 ? 195.854 258.894 248.700 1.00 34.97  ? 107 ILE E CA  1 
ATOM   12005 C  C   . ILE E 1 107 ? 194.578 258.318 248.096 1.00 36.33  ? 107 ILE E C   1 
ATOM   12006 O  O   . ILE E 1 107 ? 194.029 257.328 248.598 1.00 39.91  ? 107 ILE E O   1 
ATOM   12007 C  CB  . ILE E 1 107 ? 195.561 260.069 249.650 1.00 35.46  ? 107 ILE E CB  1 
ATOM   12008 C  CG1 . ILE E 1 107 ? 196.835 260.489 250.382 1.00 36.50  ? 107 ILE E CG1 1 
ATOM   12009 C  CG2 . ILE E 1 107 ? 194.502 259.679 250.662 1.00 33.51  ? 107 ILE E CG2 1 
ATOM   12010 C  CD1 . ILE E 1 107 ? 196.695 261.769 251.169 1.00 32.26  ? 107 ILE E CD1 1 
ATOM   12011 N  N   . ILE E 1 108 ? 194.091 258.911 247.003 1.00 37.40  ? 108 ILE E N   1 
ATOM   12012 C  CA  . ILE E 1 108 ? 192.875 258.405 246.373 1.00 41.28  ? 108 ILE E CA  1 
ATOM   12013 C  C   . ILE E 1 108 ? 193.097 256.999 245.833 1.00 41.97  ? 108 ILE E C   1 
ATOM   12014 O  O   . ILE E 1 108 ? 192.235 256.124 245.971 1.00 46.70  ? 108 ILE E O   1 
ATOM   12015 C  CB  . ILE E 1 108 ? 192.395 259.368 245.272 1.00 43.69  ? 108 ILE E CB  1 
ATOM   12016 C  CG1 . ILE E 1 108 ? 191.596 260.519 245.884 1.00 40.73  ? 108 ILE E CG1 1 
ATOM   12017 C  CG2 . ILE E 1 108 ? 191.554 258.624 244.247 1.00 43.33  ? 108 ILE E CG2 1 
ATOM   12018 C  CD1 . ILE E 1 108 ? 191.469 261.721 244.980 1.00 39.75  ? 108 ILE E CD1 1 
ATOM   12019 N  N   . ARG E 1 109 ? 194.248 256.760 245.199 1.00 37.04  ? 109 ARG E N   1 
ATOM   12020 C  CA  . ARG E 1 109 ? 194.548 255.420 244.704 1.00 40.53  ? 109 ARG E CA  1 
ATOM   12021 C  C   . ARG E 1 109 ? 194.699 254.424 245.846 1.00 45.34  ? 109 ARG E C   1 
ATOM   12022 O  O   . ARG E 1 109 ? 194.236 253.283 245.745 1.00 50.29  ? 109 ARG E O   1 
ATOM   12023 C  CB  . ARG E 1 109 ? 195.809 255.445 243.844 1.00 40.27  ? 109 ARG E CB  1 
ATOM   12024 C  CG  . ARG E 1 109 ? 195.649 256.221 242.558 1.00 43.47  ? 109 ARG E CG  1 
ATOM   12025 C  CD  . ARG E 1 109 ? 196.992 256.614 241.986 1.00 47.39  ? 109 ARG E CD  1 
ATOM   12026 N  NE  . ARG E 1 109 ? 196.873 257.118 240.625 1.00 56.07  ? 109 ARG E NE  1 
ATOM   12027 C  CZ  . ARG E 1 109 ? 196.542 256.376 239.577 1.00 59.91  ? 109 ARG E CZ  1 
ATOM   12028 N  NH1 . ARG E 1 109 ? 196.292 255.083 239.698 1.00 62.99  ? 109 ARG E NH1 1 
ATOM   12029 N  NH2 . ARG E 1 109 ? 196.464 256.945 238.378 1.00 59.92  ? 109 ARG E NH2 1 
ATOM   12030 N  N   . GLU E 1 110 ? 195.350 254.829 246.939 1.00 46.11  ? 110 GLU E N   1 
ATOM   12031 C  CA  . GLU E 1 110 ? 195.476 253.930 248.081 1.00 46.14  ? 110 GLU E CA  1 
ATOM   12032 C  C   . GLU E 1 110 ? 194.109 253.563 248.641 1.00 49.18  ? 110 GLU E C   1 
ATOM   12033 O  O   . GLU E 1 110 ? 193.893 252.427 249.077 1.00 56.70  ? 110 GLU E O   1 
ATOM   12034 C  CB  . GLU E 1 110 ? 196.349 254.563 249.164 1.00 43.62  ? 110 GLU E CB  1 
ATOM   12035 C  CG  . GLU E 1 110 ? 197.842 254.350 248.969 1.00 48.21  ? 110 GLU E CG  1 
ATOM   12036 C  CD  . GLU E 1 110 ? 198.378 253.192 249.789 1.00 56.83  ? 110 GLU E CD  1 
ATOM   12037 O  OE1 . GLU E 1 110 ? 197.591 252.282 250.120 1.00 59.50  ? 110 GLU E OE1 1 
ATOM   12038 O  OE2 . GLU E 1 110 ? 199.587 253.189 250.105 1.00 56.76  ? 110 GLU E OE2 1 
ATOM   12039 N  N   . ARG E 1 111 ? 193.173 254.512 248.641 1.00 50.57  ? 111 ARG E N   1 
ATOM   12040 C  CA  . ARG E 1 111 ? 191.833 254.214 249.134 1.00 52.81  ? 111 ARG E CA  1 
ATOM   12041 C  C   . ARG E 1 111 ? 191.030 253.369 248.152 1.00 54.26  ? 111 ARG E C   1 
ATOM   12042 O  O   . ARG E 1 111 ? 190.219 252.539 248.578 1.00 59.86  ? 111 ARG E O   1 
ATOM   12043 C  CB  . ARG E 1 111 ? 191.088 255.510 249.451 1.00 47.73  ? 111 ARG E CB  1 
ATOM   12044 C  CG  . ARG E 1 111 ? 191.883 256.454 250.330 1.00 48.19  ? 111 ARG E CG  1 
ATOM   12045 C  CD  . ARG E 1 111 ? 191.006 257.160 251.341 1.00 48.41  ? 111 ARG E CD  1 
ATOM   12046 N  NE  . ARG E 1 111 ? 191.747 257.483 252.553 1.00 49.78  ? 111 ARG E NE  1 
ATOM   12047 C  CZ  . ARG E 1 111 ? 191.694 258.654 253.172 1.00 49.25  ? 111 ARG E CZ  1 
ATOM   12048 N  NH1 . ARG E 1 111 ? 190.945 259.643 252.715 1.00 47.79  ? 111 ARG E NH1 1 
ATOM   12049 N  NH2 . ARG E 1 111 ? 192.412 258.837 254.275 1.00 45.00  ? 111 ARG E NH2 1 
ATOM   12050 N  N   . LEU E 1 112 ? 191.233 253.562 246.848 1.00 54.74  ? 112 LEU E N   1 
ATOM   12051 C  CA  . LEU E 1 112 ? 190.501 252.777 245.858 1.00 55.38  ? 112 LEU E CA  1 
ATOM   12052 C  C   . LEU E 1 112 ? 190.791 251.290 246.017 1.00 64.12  ? 112 LEU E C   1 
ATOM   12053 O  O   . LEU E 1 112 ? 189.872 250.464 246.033 1.00 69.88  ? 112 LEU E O   1 
ATOM   12054 C  CB  . LEU E 1 112 ? 190.861 253.247 244.448 1.00 51.15  ? 112 LEU E CB  1 
ATOM   12055 C  CG  . LEU E 1 112 ? 190.185 254.528 243.958 1.00 52.93  ? 112 LEU E CG  1 
ATOM   12056 C  CD1 . LEU E 1 112 ? 190.913 255.091 242.751 1.00 57.18  ? 112 LEU E CD1 1 
ATOM   12057 C  CD2 . LEU E 1 112 ? 188.726 254.273 243.629 1.00 60.51  ? 112 LEU E CD2 1 
ATOM   12058 N  N   . ALA E 1 113 ? 192.065 250.931 246.133 1.00 63.74  ? 113 ALA E N   1 
ATOM   12059 C  CA  . ALA E 1 113 ? 192.458 249.545 246.375 1.00 66.90  ? 113 ALA E CA  1 
ATOM   12060 C  C   . ALA E 1 113 ? 192.447 249.225 247.865 1.00 67.10  ? 113 ALA E C   1 
ATOM   12061 O  O   . ALA E 1 113 ? 193.415 248.717 248.426 1.00 71.61  ? 113 ALA E O   1 
ATOM   12062 C  CB  . ALA E 1 113 ? 193.829 249.279 245.766 1.00 67.76  ? 113 ALA E CB  1 
ATOM   12063 N  N   . ASP E 1 114 ? 191.325 249.526 248.517 1.00 68.35  ? 114 ASP E N   1 
ATOM   12064 C  CA  . ASP E 1 114 ? 191.158 249.309 249.941 1.00 72.21  ? 114 ASP E CA  1 
ATOM   12065 C  C   . ASP E 1 114 ? 189.780 248.713 250.191 1.00 78.46  ? 114 ASP E C   1 
ATOM   12066 O  O   . ASP E 1 114 ? 188.799 249.129 249.557 1.00 75.52  ? 114 ASP E O   1 
ATOM   12067 C  CB  . ASP E 1 114 ? 191.311 250.617 250.728 1.00 68.94  ? 114 ASP E CB  1 
ATOM   12068 C  CG  . ASP E 1 114 ? 191.452 250.389 252.218 1.00 74.41  ? 114 ASP E CG  1 
ATOM   12069 O  OD1 . ASP E 1 114 ? 192.219 249.486 252.613 1.00 75.00  ? 114 ASP E OD1 1 
ATOM   12070 O  OD2 . ASP E 1 114 ? 190.795 251.112 252.996 1.00 76.64  ? 114 ASP E OD2 1 
ATOM   12071 N  N   . PRO E 1 115 ? 189.674 247.739 251.098 1.00 82.53  ? 115 PRO E N   1 
ATOM   12072 C  CA  . PRO E 1 115 ? 188.351 247.155 251.378 1.00 80.35  ? 115 PRO E CA  1 
ATOM   12073 C  C   . PRO E 1 115 ? 187.345 248.164 251.900 1.00 79.17  ? 115 PRO E C   1 
ATOM   12074 O  O   . PRO E 1 115 ? 186.151 248.059 251.593 1.00 78.10  ? 115 PRO E O   1 
ATOM   12075 C  CB  . PRO E 1 115 ? 188.666 246.071 252.419 1.00 75.67  ? 115 PRO E CB  1 
ATOM   12076 C  CG  . PRO E 1 115 ? 190.116 245.762 252.218 1.00 76.21  ? 115 PRO E CG  1 
ATOM   12077 C  CD  . PRO E 1 115 ? 190.745 247.067 251.850 1.00 75.36  ? 115 PRO E CD  1 
ATOM   12078 N  N   . ALA E 1 116 ? 187.794 249.144 252.688 1.00 79.00  ? 116 ALA E N   1 
ATOM   12079 C  CA  . ALA E 1 116 ? 186.861 250.075 253.313 1.00 78.32  ? 116 ALA E CA  1 
ATOM   12080 C  C   . ALA E 1 116 ? 186.137 250.927 252.279 1.00 77.71  ? 116 ALA E C   1 
ATOM   12081 O  O   . ALA E 1 116 ? 184.919 251.118 252.368 1.00 73.41  ? 116 ALA E O   1 
ATOM   12082 C  CB  . ALA E 1 116 ? 187.599 250.964 254.313 1.00 74.62  ? 116 ALA E CB  1 
ATOM   12083 N  N   . TYR E 1 117 ? 186.865 251.452 251.293 1.00 77.92  ? 117 TYR E N   1 
ATOM   12084 C  CA  . TYR E 1 117 ? 186.291 252.369 250.315 1.00 75.60  ? 117 TYR E CA  1 
ATOM   12085 C  C   . TYR E 1 117 ? 185.968 251.670 248.999 1.00 77.75  ? 117 TYR E C   1 
ATOM   12086 O  O   . TYR E 1 117 ? 184.816 251.662 248.559 1.00 86.94  ? 117 TYR E O   1 
ATOM   12087 C  CB  . TYR E 1 117 ? 187.254 253.539 250.077 1.00 69.83  ? 117 TYR E CB  1 
ATOM   12088 C  CG  . TYR E 1 117 ? 187.480 254.408 251.293 1.00 66.87  ? 117 TYR E CG  1 
ATOM   12089 C  CD1 . TYR E 1 117 ? 186.640 255.477 251.576 1.00 63.14  ? 117 TYR E CD1 1 
ATOM   12090 C  CD2 . TYR E 1 117 ? 188.540 254.164 252.154 1.00 66.68  ? 117 TYR E CD2 1 
ATOM   12091 C  CE1 . TYR E 1 117 ? 186.849 256.273 252.685 1.00 66.31  ? 117 TYR E CE1 1 
ATOM   12092 C  CE2 . TYR E 1 117 ? 188.757 254.954 253.265 1.00 66.22  ? 117 TYR E CE2 1 
ATOM   12093 C  CZ  . TYR E 1 117 ? 187.908 256.007 253.526 1.00 66.17  ? 117 TYR E CZ  1 
ATOM   12094 O  OH  . TYR E 1 117 ? 188.123 256.796 254.633 1.00 57.21  ? 117 TYR E OH  1 
ATOM   12095 N  N   . GLY E 1 118 ? 186.973 251.074 248.366 1.00 76.25  ? 118 GLY E N   1 
ATOM   12096 C  CA  . GLY E 1 118 ? 186.777 250.376 247.112 1.00 79.18  ? 118 GLY E CA  1 
ATOM   12097 C  C   . GLY E 1 118 ? 186.990 248.882 247.227 1.00 83.47  ? 118 GLY E C   1 
ATOM   12098 O  O   . GLY E 1 118 ? 186.110 248.147 247.685 1.00 83.92  ? 118 GLY E O   1 
ATOM   12099 N  N   . GLY E 1 119 ? 188.164 248.423 246.804 1.00 79.21  ? 119 GLY E N   1 
ATOM   12100 C  CA  . GLY E 1 119 ? 188.480 247.011 246.811 1.00 78.84  ? 119 GLY E CA  1 
ATOM   12101 C  C   . GLY E 1 119 ? 189.150 246.577 245.525 1.00 79.20  ? 119 GLY E C   1 
ATOM   12102 O  O   . GLY E 1 119 ? 189.657 245.457 245.424 1.00 85.64  ? 119 GLY E O   1 
ATOM   12103 N  N   . ASN E 1 120 ? 189.159 247.463 244.534 1.00 73.97  ? 120 ASN E N   1 
ATOM   12104 C  CA  . ASN E 1 120 ? 189.755 247.158 243.237 1.00 77.54  ? 120 ASN E CA  1 
ATOM   12105 C  C   . ASN E 1 120 ? 191.261 247.030 243.408 1.00 80.02  ? 120 ASN E C   1 
ATOM   12106 O  O   . ASN E 1 120 ? 191.973 248.027 243.534 1.00 79.97  ? 120 ASN E O   1 
ATOM   12107 C  CB  . ASN E 1 120 ? 189.404 248.243 242.227 1.00 76.94  ? 120 ASN E CB  1 
ATOM   12108 C  CG  . ASN E 1 120 ? 189.473 247.752 240.800 1.00 84.21  ? 120 ASN E CG  1 
ATOM   12109 O  OD1 . ASN E 1 120 ? 189.464 246.550 240.544 1.00 86.94  ? 120 ASN E OD1 1 
ATOM   12110 N  ND2 . ASN E 1 120 ? 189.539 248.685 239.857 1.00 83.83  ? 120 ASN E ND2 1 
ATOM   12111 N  N   . GLU E 1 121 ? 191.754 245.791 243.395 1.00 82.42  ? 121 GLU E N   1 
ATOM   12112 C  CA  . GLU E 1 121 ? 193.172 245.536 243.606 1.00 81.69  ? 121 GLU E CA  1 
ATOM   12113 C  C   . GLU E 1 121 ? 194.030 245.966 242.427 1.00 79.90  ? 121 GLU E C   1 
ATOM   12114 O  O   . GLU E 1 121 ? 195.260 245.968 242.548 1.00 84.80  ? 121 GLU E O   1 
ATOM   12115 C  CB  . GLU E 1 121 ? 193.395 244.053 243.901 1.00 85.75  ? 121 GLU E CB  1 
ATOM   12116 C  CG  . GLU E 1 121 ? 192.357 243.459 244.837 1.00 90.05  ? 121 GLU E CG  1 
ATOM   12117 C  CD  . GLU E 1 121 ? 192.477 243.996 246.249 1.00 94.01  ? 121 GLU E CD  1 
ATOM   12118 O  OE1 . GLU E 1 121 ? 193.476 244.687 246.539 1.00 87.82  ? 121 GLU E OE1 1 
ATOM   12119 O  OE2 . GLU E 1 121 ? 191.573 243.728 247.069 1.00 93.08  ? 121 GLU E OE2 1 
ATOM   12120 N  N   . GLU E 1 122 ? 193.420 246.323 241.297 1.00 79.17  ? 122 GLU E N   1 
ATOM   12121 C  CA  . GLU E 1 122 ? 194.198 246.779 240.154 1.00 83.99  ? 122 GLU E CA  1 
ATOM   12122 C  C   . GLU E 1 122 ? 194.948 248.069 240.454 1.00 84.16  ? 122 GLU E C   1 
ATOM   12123 O  O   . GLU E 1 122 ? 195.891 248.409 239.733 1.00 85.75  ? 122 GLU E O   1 
ATOM   12124 C  CB  . GLU E 1 122 ? 193.282 246.965 238.945 1.00 85.45  ? 122 GLU E CB  1 
ATOM   12125 C  CG  . GLU E 1 122 ? 192.521 245.708 238.556 1.00 89.21  ? 122 GLU E CG  1 
ATOM   12126 C  CD  . GLU E 1 122 ? 191.253 246.011 237.783 1.00 101.04 ? 122 GLU E CD  1 
ATOM   12127 O  OE1 . GLU E 1 122 ? 190.979 247.203 237.535 1.00 101.35 ? 122 GLU E OE1 1 
ATOM   12128 O  OE2 . GLU E 1 122 ? 190.529 245.057 237.428 1.00 101.17 ? 122 GLU E OE2 1 
ATOM   12129 N  N   . TYR E 1 123 ? 194.555 248.787 241.505 1.00 80.11  ? 123 TYR E N   1 
ATOM   12130 C  CA  . TYR E 1 123 ? 195.209 250.027 241.894 1.00 75.47  ? 123 TYR E CA  1 
ATOM   12131 C  C   . TYR E 1 123 ? 196.432 249.812 242.776 1.00 74.80  ? 123 TYR E C   1 
ATOM   12132 O  O   . TYR E 1 123 ? 197.147 250.779 243.059 1.00 75.84  ? 123 TYR E O   1 
ATOM   12133 C  CB  . TYR E 1 123 ? 194.216 250.939 242.623 1.00 69.68  ? 123 TYR E CB  1 
ATOM   12134 C  CG  . TYR E 1 123 ? 193.191 251.579 241.716 1.00 71.11  ? 123 TYR E CG  1 
ATOM   12135 C  CD1 . TYR E 1 123 ? 193.549 252.593 240.840 1.00 69.53  ? 123 TYR E CD1 1 
ATOM   12136 C  CD2 . TYR E 1 123 ? 191.864 251.171 241.738 1.00 69.99  ? 123 TYR E CD2 1 
ATOM   12137 C  CE1 . TYR E 1 123 ? 192.617 253.183 240.011 1.00 69.43  ? 123 TYR E CE1 1 
ATOM   12138 C  CE2 . TYR E 1 123 ? 190.925 251.755 240.912 1.00 70.83  ? 123 TYR E CE2 1 
ATOM   12139 C  CZ  . TYR E 1 123 ? 191.307 252.761 240.051 1.00 68.60  ? 123 TYR E CZ  1 
ATOM   12140 O  OH  . TYR E 1 123 ? 190.375 253.346 239.226 1.00 70.14  ? 123 TYR E OH  1 
ATOM   12141 N  N   . LYS E 1 124 ? 196.691 248.581 243.217 1.00 75.63  ? 124 LYS E N   1 
ATOM   12142 C  CA  . LYS E 1 124 ? 197.838 248.283 244.076 1.00 74.32  ? 124 LYS E CA  1 
ATOM   12143 C  C   . LYS E 1 124 ? 198.484 246.994 243.577 1.00 77.76  ? 124 LYS E C   1 
ATOM   12144 O  O   . LYS E 1 124 ? 198.006 245.897 243.877 1.00 81.91  ? 124 LYS E O   1 
ATOM   12145 C  CB  . LYS E 1 124 ? 197.422 248.163 245.537 1.00 74.99  ? 124 LYS E CB  1 
ATOM   12146 C  CG  . LYS E 1 124 ? 198.560 248.372 246.523 1.00 71.54  ? 124 LYS E CG  1 
ATOM   12147 C  CD  . LYS E 1 124 ? 198.078 249.050 247.794 1.00 64.94  ? 124 LYS E CD  1 
ATOM   12148 C  CE  . LYS E 1 124 ? 199.205 249.193 248.802 1.00 68.87  ? 124 LYS E CE  1 
ATOM   12149 N  NZ  . LYS E 1 124 ? 200.505 249.488 248.143 1.00 75.02  ? 124 LYS E NZ  1 
ATOM   12150 N  N   . ILE E 1 125 ? 199.570 247.133 242.816 1.00 77.92  ? 125 ILE E N   1 
ATOM   12151 C  CA  . ILE E 1 125 ? 200.293 245.971 242.315 1.00 80.86  ? 125 ILE E CA  1 
ATOM   12152 C  C   . ILE E 1 125 ? 201.000 245.276 243.469 1.00 83.87  ? 125 ILE E C   1 
ATOM   12153 O  O   . ILE E 1 125 ? 201.668 245.919 244.289 1.00 83.13  ? 125 ILE E O   1 
ATOM   12154 C  CB  . ILE E 1 125 ? 201.291 246.385 241.225 1.00 81.23  ? 125 ILE E CB  1 
ATOM   12155 C  CG1 . ILE E 1 125 ? 200.560 247.037 240.049 1.00 78.73  ? 125 ILE E CG1 1 
ATOM   12156 C  CG2 . ILE E 1 125 ? 202.098 245.183 240.762 1.00 84.25  ? 125 ILE E CG2 1 
ATOM   12157 C  CD1 . ILE E 1 125 ? 201.358 247.038 238.763 1.00 72.25  ? 125 ILE E CD1 1 
ATOM   12158 N  N   . THR E 1 126 ? 200.857 243.951 243.538 1.00 89.42  ? 126 THR E N   1 
ATOM   12159 C  CA  . THR E 1 126 ? 201.495 243.160 244.583 1.00 93.65  ? 126 THR E CA  1 
ATOM   12160 C  C   . THR E 1 126 ? 202.181 241.913 244.038 1.00 102.09 ? 126 THR E C   1 
ATOM   12161 O  O   . THR E 1 126 ? 202.635 241.078 244.829 1.00 101.49 ? 126 THR E O   1 
ATOM   12162 C  CB  . THR E 1 126 ? 200.476 242.757 245.655 1.00 92.53  ? 126 THR E CB  1 
ATOM   12163 O  OG1 . THR E 1 126 ? 199.637 241.711 245.150 1.00 94.56  ? 126 THR E OG1 1 
ATOM   12164 C  CG2 . THR E 1 126 ? 199.613 243.947 246.046 1.00 87.23  ? 126 THR E CG2 1 
ATOM   12165 N  N   . GLU E 1 127 ? 202.271 241.763 242.719 1.00 106.30 ? 127 GLU E N   1 
ATOM   12166 C  CA  . GLU E 1 127 ? 202.892 240.588 242.126 1.00 111.46 ? 127 GLU E CA  1 
ATOM   12167 C  C   . GLU E 1 127 ? 203.420 240.941 240.745 1.00 114.52 ? 127 GLU E C   1 
ATOM   12168 O  O   . GLU E 1 127 ? 202.990 241.915 240.121 1.00 112.98 ? 127 GLU E O   1 
ATOM   12169 C  CB  . GLU E 1 127 ? 201.909 239.415 242.031 1.00 111.76 ? 127 GLU E CB  1 
ATOM   12170 C  CG  . GLU E 1 127 ? 201.519 238.813 243.369 1.00 109.93 ? 127 GLU E CG  1 
ATOM   12171 C  CD  . GLU E 1 127 ? 200.058 238.414 243.420 1.00 108.33 ? 127 GLU E CD  1 
ATOM   12172 O  OE1 . GLU E 1 127 ? 199.213 239.183 242.914 1.00 108.34 ? 127 GLU E OE1 1 
ATOM   12173 O  OE2 . GLU E 1 127 ? 199.753 237.333 243.967 1.00 108.70 ? 127 GLU E OE2 1 
ATOM   12174 N  N   . ASN E 1 128 ? 204.361 240.130 240.272 1.00 121.60 ? 128 ASN E N   1 
ATOM   12175 C  CA  . ASN E 1 128 ? 204.893 240.284 238.930 1.00 126.64 ? 128 ASN E CA  1 
ATOM   12176 C  C   . ASN E 1 128 ? 204.009 239.552 237.922 1.00 129.16 ? 128 ASN E C   1 
ATOM   12177 O  O   . ASN E 1 128 ? 203.092 238.807 238.280 1.00 128.08 ? 128 ASN E O   1 
ATOM   12178 C  CB  . ASN E 1 128 ? 206.326 239.760 238.856 1.00 127.06 ? 128 ASN E CB  1 
ATOM   12179 C  CG  . ASN E 1 128 ? 207.326 240.703 239.493 1.00 127.56 ? 128 ASN E CG  1 
ATOM   12180 O  OD1 . ASN E 1 128 ? 207.083 241.904 239.597 1.00 128.37 ? 128 ASN E OD1 1 
ATOM   12181 N  ND2 . ASN E 1 128 ? 208.460 240.161 239.921 1.00 124.39 ? 128 ASN E ND2 1 
ATOM   12182 N  N   . LYS E 1 129 ? 204.294 239.777 236.638 1.00 131.05 ? 129 LYS E N   1 
ATOM   12183 C  CA  . LYS E 1 129 ? 203.601 239.028 235.597 1.00 132.66 ? 129 LYS E CA  1 
ATOM   12184 C  C   . LYS E 1 129 ? 203.840 237.532 235.745 1.00 133.24 ? 129 LYS E C   1 
ATOM   12185 O  O   . LYS E 1 129 ? 202.964 236.725 235.415 1.00 129.86 ? 129 LYS E O   1 
ATOM   12186 C  CB  . LYS E 1 129 ? 204.048 239.505 234.215 1.00 129.81 ? 129 LYS E CB  1 
ATOM   12187 C  CG  . LYS E 1 129 ? 203.559 240.898 233.848 1.00 126.49 ? 129 LYS E CG  1 
ATOM   12188 C  CD  . LYS E 1 129 ? 204.525 241.967 234.335 1.00 126.89 ? 129 LYS E CD  1 
ATOM   12189 C  CE  . LYS E 1 129 ? 204.124 243.347 233.839 1.00 123.31 ? 129 LYS E CE  1 
ATOM   12190 N  NZ  . LYS E 1 129 ? 204.863 244.425 234.552 1.00 112.82 ? 129 LYS E NZ  1 
ATOM   12191 N  N   . PHE E 1 130 ? 205.014 237.147 236.240 1.00 134.54 ? 130 PHE E N   1 
ATOM   12192 C  CA  . PHE E 1 130 ? 205.353 235.748 236.461 1.00 133.67 ? 130 PHE E CA  1 
ATOM   12193 C  C   . PHE E 1 130 ? 204.794 235.202 237.768 1.00 129.62 ? 130 PHE E C   1 
ATOM   12194 O  O   . PHE E 1 130 ? 204.927 234.001 238.025 1.00 127.25 ? 130 PHE E O   1 
ATOM   12195 C  CB  . PHE E 1 130 ? 206.873 235.571 236.438 1.00 133.71 ? 130 PHE E CB  1 
ATOM   12196 C  CG  . PHE E 1 130 ? 207.589 236.616 235.633 1.00 134.11 ? 130 PHE E CG  1 
ATOM   12197 C  CD1 . PHE E 1 130 ? 207.414 236.695 234.262 1.00 134.08 ? 130 PHE E CD1 1 
ATOM   12198 C  CD2 . PHE E 1 130 ? 208.434 237.524 236.248 1.00 134.26 ? 130 PHE E CD2 1 
ATOM   12199 C  CE1 . PHE E 1 130 ? 208.070 237.656 233.519 1.00 135.01 ? 130 PHE E CE1 1 
ATOM   12200 C  CE2 . PHE E 1 130 ? 209.093 238.489 235.510 1.00 134.20 ? 130 PHE E CE2 1 
ATOM   12201 C  CZ  . PHE E 1 130 ? 208.911 238.555 234.144 1.00 134.27 ? 130 PHE E CZ  1 
ATOM   12202 N  N   . GLY E 1 131 ? 204.176 236.044 238.591 1.00 127.24 ? 131 GLY E N   1 
ATOM   12203 C  CA  . GLY E 1 131 ? 203.631 235.615 239.861 1.00 123.87 ? 131 GLY E CA  1 
ATOM   12204 C  C   . GLY E 1 131 ? 204.559 235.750 241.046 1.00 126.40 ? 131 GLY E C   1 
ATOM   12205 O  O   . GLY E 1 131 ? 204.208 235.291 242.139 1.00 122.32 ? 131 GLY E O   1 
ATOM   12206 N  N   . GLU E 1 132 ? 205.723 236.359 240.872 1.00 130.46 ? 132 GLU E N   1 
ATOM   12207 C  CA  . GLU E 1 132 ? 206.650 236.541 241.983 1.00 127.11 ? 132 GLU E CA  1 
ATOM   12208 C  C   . GLU E 1 132 ? 206.125 237.614 242.926 1.00 123.40 ? 132 GLU E C   1 
ATOM   12209 O  O   . GLU E 1 132 ? 205.906 238.753 242.490 1.00 120.21 ? 132 GLU E O   1 
ATOM   12210 C  CB  . GLU E 1 132 ? 208.032 236.929 241.467 1.00 127.77 ? 132 GLU E CB  1 
ATOM   12211 C  CG  . GLU E 1 132 ? 208.661 235.923 240.520 1.00 129.46 ? 132 GLU E CG  1 
ATOM   12212 C  CD  . GLU E 1 132 ? 209.981 236.410 239.956 1.00 131.21 ? 132 GLU E CD  1 
ATOM   12213 O  OE1 . GLU E 1 132 ? 211.014 236.261 240.643 1.00 122.16 ? 132 GLU E OE1 1 
ATOM   12214 O  OE2 . GLU E 1 132 ? 209.987 236.945 238.828 1.00 134.69 ? 132 GLU E OE2 1 
ATOM   12215 N  N   . PRO E 1 133 ? 205.904 237.311 244.203 1.00 122.52 ? 133 PRO E N   1 
ATOM   12216 C  CA  . PRO E 1 133 ? 205.496 238.362 245.144 1.00 117.93 ? 133 PRO E CA  1 
ATOM   12217 C  C   . PRO E 1 133 ? 206.526 239.482 245.178 1.00 117.11 ? 133 PRO E C   1 
ATOM   12218 O  O   . PRO E 1 133 ? 207.734 239.238 245.203 1.00 116.34 ? 133 PRO E O   1 
ATOM   12219 C  CB  . PRO E 1 133 ? 205.408 237.624 246.485 1.00 112.30 ? 133 PRO E CB  1 
ATOM   12220 C  CG  . PRO E 1 133 ? 205.209 236.189 246.116 1.00 115.33 ? 133 PRO E CG  1 
ATOM   12221 C  CD  . PRO E 1 133 ? 205.966 235.985 244.839 1.00 118.09 ? 133 PRO E CD  1 
ATOM   12222 N  N   . VAL E 1 134 ? 206.035 240.721 245.179 1.00 112.99 ? 134 VAL E N   1 
ATOM   12223 C  CA  . VAL E 1 134 ? 206.881 241.903 245.122 1.00 106.56 ? 134 VAL E CA  1 
ATOM   12224 C  C   . VAL E 1 134 ? 206.349 242.935 246.108 1.00 100.77 ? 134 VAL E C   1 
ATOM   12225 O  O   . VAL E 1 134 ? 205.270 242.785 246.682 1.00 96.52  ? 134 VAL E O   1 
ATOM   12226 C  CB  . VAL E 1 134 ? 206.959 242.498 243.700 1.00 105.37 ? 134 VAL E CB  1 
ATOM   12227 C  CG1 . VAL E 1 134 ? 205.682 243.254 243.368 1.00 99.35  ? 134 VAL E CG1 1 
ATOM   12228 C  CG2 . VAL E 1 134 ? 208.177 243.401 243.564 1.00 99.25  ? 134 VAL E CG2 1 
ATOM   12229 N  N   . THR E 1 135 ? 207.129 243.992 246.298 1.00 97.61  ? 135 THR E N   1 
ATOM   12230 C  CA  . THR E 1 135 ? 206.740 245.050 247.218 1.00 90.26  ? 135 THR E CA  1 
ATOM   12231 C  C   . THR E 1 135 ? 205.419 245.669 246.772 1.00 85.19  ? 135 THR E C   1 
ATOM   12232 O  O   . THR E 1 135 ? 205.286 246.057 245.603 1.00 85.23  ? 135 THR E O   1 
ATOM   12233 C  CB  . THR E 1 135 ? 207.824 246.124 247.288 1.00 86.85  ? 135 THR E CB  1 
ATOM   12234 O  OG1 . THR E 1 135 ? 209.116 245.506 247.237 1.00 87.99  ? 135 THR E OG1 1 
ATOM   12235 C  CG2 . THR E 1 135 ? 207.699 246.924 248.574 1.00 80.99  ? 135 THR E CG2 1 
ATOM   12236 N  N   . PRO E 1 136 ? 204.429 245.778 247.656 1.00 82.87  ? 136 PRO E N   1 
ATOM   12237 C  CA  . PRO E 1 136 ? 203.150 246.385 247.259 1.00 82.02  ? 136 PRO E CA  1 
ATOM   12238 C  C   . PRO E 1 136 ? 203.327 247.863 246.943 1.00 77.89  ? 136 PRO E C   1 
ATOM   12239 O  O   . PRO E 1 136 ? 203.849 248.628 247.756 1.00 76.09  ? 136 PRO E O   1 
ATOM   12240 C  CB  . PRO E 1 136 ? 202.255 246.172 248.487 1.00 79.14  ? 136 PRO E CB  1 
ATOM   12241 C  CG  . PRO E 1 136 ? 202.946 245.121 249.305 1.00 81.94  ? 136 PRO E CG  1 
ATOM   12242 C  CD  . PRO E 1 136 ? 204.405 245.290 249.043 1.00 81.44  ? 136 PRO E CD  1 
ATOM   12243 N  N   . HIS E 1 137 ? 202.884 248.260 245.752 1.00 74.68  ? 137 HIS E N   1 
ATOM   12244 C  CA  . HIS E 1 137 ? 203.010 249.643 245.322 1.00 71.68  ? 137 HIS E CA  1 
ATOM   12245 C  C   . HIS E 1 137 ? 201.845 249.991 244.409 1.00 67.85  ? 137 HIS E C   1 
ATOM   12246 O  O   . HIS E 1 137 ? 201.205 249.115 243.824 1.00 70.97  ? 137 HIS E O   1 
ATOM   12247 C  CB  . HIS E 1 137 ? 204.345 249.894 244.610 1.00 71.20  ? 137 HIS E CB  1 
ATOM   12248 C  CG  . HIS E 1 137 ? 204.547 249.052 243.389 1.00 75.27  ? 137 HIS E CG  1 
ATOM   12249 N  ND1 . HIS E 1 137 ? 204.652 247.679 243.442 1.00 78.22  ? 137 HIS E ND1 1 
ATOM   12250 C  CD2 . HIS E 1 137 ? 204.660 249.388 242.082 1.00 74.20  ? 137 HIS E CD2 1 
ATOM   12251 C  CE1 . HIS E 1 137 ? 204.824 247.206 242.221 1.00 78.59  ? 137 HIS E CE1 1 
ATOM   12252 N  NE2 . HIS E 1 137 ? 204.832 248.222 241.377 1.00 76.42  ? 137 HIS E NE2 1 
ATOM   12253 N  N   . LEU E 1 138 ? 201.577 251.288 244.297 1.00 64.09  ? 138 LEU E N   1 
ATOM   12254 C  CA  . LEU E 1 138 ? 200.486 251.762 243.462 1.00 62.78  ? 138 LEU E CA  1 
ATOM   12255 C  C   . LEU E 1 138 ? 200.819 251.590 241.985 1.00 65.96  ? 138 LEU E C   1 
ATOM   12256 O  O   . LEU E 1 138 ? 201.984 251.607 241.579 1.00 66.57  ? 138 LEU E O   1 
ATOM   12257 C  CB  . LEU E 1 138 ? 200.184 253.231 243.757 1.00 56.48  ? 138 LEU E CB  1 
ATOM   12258 C  CG  . LEU E 1 138 ? 199.771 253.579 245.188 1.00 54.31  ? 138 LEU E CG  1 
ATOM   12259 C  CD1 . LEU E 1 138 ? 199.555 255.076 245.328 1.00 46.44  ? 138 LEU E CD1 1 
ATOM   12260 C  CD2 . LEU E 1 138 ? 198.526 252.810 245.595 1.00 52.09  ? 138 LEU E CD2 1 
ATOM   12261 N  N   . ASP E 1 139 ? 199.776 251.423 241.178 1.00 66.96  ? 139 ASP E N   1 
ATOM   12262 C  CA  . ASP E 1 139 ? 199.893 251.311 239.726 1.00 70.93  ? 139 ASP E CA  1 
ATOM   12263 C  C   . ASP E 1 139 ? 199.357 252.606 239.119 1.00 70.61  ? 139 ASP E C   1 
ATOM   12264 O  O   . ASP E 1 139 ? 198.162 252.737 238.853 1.00 73.77  ? 139 ASP E O   1 
ATOM   12265 C  CB  . ASP E 1 139 ? 199.136 250.095 239.205 1.00 73.65  ? 139 ASP E CB  1 
ATOM   12266 C  CG  . ASP E 1 139 ? 199.282 249.918 237.707 1.00 76.97  ? 139 ASP E CG  1 
ATOM   12267 O  OD1 . ASP E 1 139 ? 200.395 250.141 237.187 1.00 76.70  ? 139 ASP E OD1 1 
ATOM   12268 O  OD2 . ASP E 1 139 ? 198.282 249.565 237.049 1.00 76.10  ? 139 ASP E OD2 1 
ATOM   12269 N  N   . TRP E 1 140 ? 200.256 253.565 238.896 1.00 65.24  ? 140 TRP E N   1 
ATOM   12270 C  CA  . TRP E 1 140 ? 199.858 254.860 238.360 1.00 65.85  ? 140 TRP E CA  1 
ATOM   12271 C  C   . TRP E 1 140 ? 199.473 254.799 236.888 1.00 72.70  ? 140 TRP E C   1 
ATOM   12272 O  O   . TRP E 1 140 ? 198.976 255.798 236.356 1.00 71.70  ? 140 TRP E O   1 
ATOM   12273 C  CB  . TRP E 1 140 ? 200.985 255.876 238.555 1.00 61.78  ? 140 TRP E CB  1 
ATOM   12274 C  CG  . TRP E 1 140 ? 201.301 256.147 239.992 1.00 59.24  ? 140 TRP E CG  1 
ATOM   12275 C  CD1 . TRP E 1 140 ? 202.066 255.382 240.819 1.00 57.81  ? 140 TRP E CD1 1 
ATOM   12276 C  CD2 . TRP E 1 140 ? 200.857 257.263 240.773 1.00 56.96  ? 140 TRP E CD2 1 
ATOM   12277 N  NE1 . TRP E 1 140 ? 202.129 255.950 242.067 1.00 55.77  ? 140 TRP E NE1 1 
ATOM   12278 C  CE2 . TRP E 1 140 ? 201.395 257.106 242.065 1.00 54.06  ? 140 TRP E CE2 1 
ATOM   12279 C  CE3 . TRP E 1 140 ? 200.059 258.379 240.506 1.00 51.05  ? 140 TRP E CE3 1 
ATOM   12280 C  CZ2 . TRP E 1 140 ? 201.160 258.023 243.086 1.00 43.72  ? 140 TRP E CZ2 1 
ATOM   12281 C  CZ3 . TRP E 1 140 ? 199.827 259.286 241.521 1.00 45.82  ? 140 TRP E CZ3 1 
ATOM   12282 C  CH2 . TRP E 1 140 ? 200.376 259.103 242.795 1.00 40.65  ? 140 TRP E CH2 1 
ATOM   12283 N  N   . SER E 1 141 ? 199.694 253.667 236.218 1.00 76.81  ? 141 SER E N   1 
ATOM   12284 C  CA  . SER E 1 141 ? 199.362 253.574 234.800 1.00 75.19  ? 141 SER E CA  1 
ATOM   12285 C  C   . SER E 1 141 ? 197.862 253.711 234.570 1.00 74.39  ? 141 SER E C   1 
ATOM   12286 O  O   . SER E 1 141 ? 197.431 254.389 233.630 1.00 78.73  ? 141 SER E O   1 
ATOM   12287 C  CB  . SER E 1 141 ? 199.873 252.253 234.226 1.00 74.07  ? 141 SER E CB  1 
ATOM   12288 O  OG  . SER E 1 141 ? 199.323 251.149 234.923 1.00 81.93  ? 141 SER E OG  1 
ATOM   12289 N  N   . LYS E 1 142 ? 197.054 253.075 235.408 1.00 69.31  ? 142 LYS E N   1 
ATOM   12290 C  CA  . LYS E 1 142 ? 195.609 253.108 235.215 1.00 71.22  ? 142 LYS E CA  1 
ATOM   12291 C  C   . LYS E 1 142 ? 195.042 254.431 235.719 1.00 74.39  ? 142 LYS E C   1 
ATOM   12292 O  O   . LYS E 1 142 ? 195.332 254.831 236.850 1.00 73.88  ? 142 LYS E O   1 
ATOM   12293 C  CB  . LYS E 1 142 ? 194.942 251.941 235.933 1.00 72.23  ? 142 LYS E CB  1 
ATOM   12294 C  CG  . LYS E 1 142 ? 195.405 251.738 237.362 1.00 76.83  ? 142 LYS E CG  1 
ATOM   12295 C  CD  . LYS E 1 142 ? 194.891 250.419 237.913 1.00 80.69  ? 142 LYS E CD  1 
ATOM   12296 C  CE  . LYS E 1 142 ? 193.508 250.088 237.372 1.00 81.21  ? 142 LYS E CE  1 
ATOM   12297 N  NZ  . LYS E 1 142 ? 192.514 251.155 237.662 1.00 79.17  ? 142 LYS E NZ  1 
ATOM   12298 N  N   . PRO E 1 143 ? 194.243 255.129 234.918 1.00 75.21  ? 143 PRO E N   1 
ATOM   12299 C  CA  . PRO E 1 143 ? 193.710 256.423 235.356 1.00 74.69  ? 143 PRO E CA  1 
ATOM   12300 C  C   . PRO E 1 143 ? 192.705 256.270 236.485 1.00 75.39  ? 143 PRO E C   1 
ATOM   12301 O  O   . PRO E 1 143 ? 192.028 255.247 236.617 1.00 74.92  ? 143 PRO E O   1 
ATOM   12302 C  CB  . PRO E 1 143 ? 193.044 256.976 234.092 1.00 77.19  ? 143 PRO E CB  1 
ATOM   12303 C  CG  . PRO E 1 143 ? 192.677 255.763 233.309 1.00 76.78  ? 143 PRO E CG  1 
ATOM   12304 C  CD  . PRO E 1 143 ? 193.752 254.747 233.583 1.00 72.39  ? 143 PRO E CD  1 
ATOM   12305 N  N   . ILE E 1 144 ? 192.621 257.307 237.308 1.00 76.09  ? 144 ILE E N   1 
ATOM   12306 C  CA  . ILE E 1 144 ? 191.625 257.329 238.387 1.00 72.47  ? 144 ILE E CA  1 
ATOM   12307 C  C   . ILE E 1 144 ? 190.241 257.529 237.783 1.00 76.25  ? 144 ILE E C   1 
ATOM   12308 O  O   . ILE E 1 144 ? 190.099 258.292 236.811 1.00 78.76  ? 144 ILE E O   1 
ATOM   12309 C  CB  . ILE E 1 144 ? 191.956 258.433 239.393 1.00 67.95  ? 144 ILE E CB  1 
ATOM   12310 C  CG1 . ILE E 1 144 ? 192.904 257.901 240.471 1.00 65.35  ? 144 ILE E CG1 1 
ATOM   12311 C  CG2 . ILE E 1 144 ? 190.684 258.988 240.013 1.00 65.43  ? 144 ILE E CG2 1 
ATOM   12312 C  CD1 . ILE E 1 144 ? 193.454 258.970 241.390 1.00 51.63  ? 144 ILE E CD1 1 
ATOM   12313 N  N   . PRO E 1 145 ? 189.204 256.878 238.306 1.00 78.08  ? 145 PRO E N   1 
ATOM   12314 C  CA  . PRO E 1 145 ? 187.876 257.004 237.695 1.00 77.56  ? 145 PRO E CA  1 
ATOM   12315 C  C   . PRO E 1 145 ? 187.371 258.438 237.744 1.00 83.15  ? 145 PRO E C   1 
ATOM   12316 O  O   . PRO E 1 145 ? 187.574 259.157 238.725 1.00 81.53  ? 145 PRO E O   1 
ATOM   12317 C  CB  . PRO E 1 145 ? 187.001 256.070 238.541 1.00 77.18  ? 145 PRO E CB  1 
ATOM   12318 C  CG  . PRO E 1 145 ? 187.955 255.241 239.351 1.00 75.62  ? 145 PRO E CG  1 
ATOM   12319 C  CD  . PRO E 1 145 ? 189.176 256.071 239.534 1.00 75.75  ? 145 PRO E CD  1 
ATOM   12320 N  N   . SER E 1 146 ? 186.703 258.849 236.671 1.00 89.56  ? 146 SER E N   1 
ATOM   12321 C  CA  . SER E 1 146 ? 186.067 260.157 236.645 1.00 91.49  ? 146 SER E CA  1 
ATOM   12322 C  C   . SER E 1 146 ? 184.863 260.176 237.578 1.00 95.43  ? 146 SER E C   1 
ATOM   12323 O  O   . SER E 1 146 ? 184.213 259.154 237.812 1.00 95.17  ? 146 SER E O   1 
ATOM   12324 C  CB  . SER E 1 146 ? 185.636 260.517 235.224 1.00 90.08  ? 146 SER E CB  1 
ATOM   12325 O  OG  . SER E 1 146 ? 184.572 261.452 235.238 1.00 94.59  ? 146 SER E OG  1 
ATOM   12326 N  N   . GLU E 1 147 ? 184.564 261.361 238.114 1.00 97.11  ? 147 GLU E N   1 
ATOM   12327 C  CA  . GLU E 1 147 ? 183.464 261.478 239.066 1.00 98.74  ? 147 GLU E CA  1 
ATOM   12328 C  C   . GLU E 1 147 ? 182.140 261.061 238.437 1.00 102.15 ? 147 GLU E C   1 
ATOM   12329 O  O   . GLU E 1 147 ? 181.299 260.441 239.099 1.00 99.55  ? 147 GLU E O   1 
ATOM   12330 C  CB  . GLU E 1 147 ? 183.385 262.907 239.603 1.00 96.22  ? 147 GLU E CB  1 
ATOM   12331 C  CG  . GLU E 1 147 ? 184.592 263.317 240.434 1.00 97.29  ? 147 GLU E CG  1 
ATOM   12332 C  CD  . GLU E 1 147 ? 184.840 264.812 240.412 1.00 103.87 ? 147 GLU E CD  1 
ATOM   12333 O  OE1 . GLU E 1 147 ? 184.213 265.510 239.587 1.00 108.34 ? 147 GLU E OE1 1 
ATOM   12334 O  OE2 . GLU E 1 147 ? 185.660 265.291 241.224 1.00 94.81  ? 147 GLU E OE2 1 
ATOM   12335 N  N   . LYS E 1 148 ? 181.933 261.393 237.162 1.00 102.25 ? 148 LYS E N   1 
ATOM   12336 C  CA  . LYS E 1 148 ? 180.704 260.995 236.486 1.00 101.79 ? 148 LYS E CA  1 
ATOM   12337 C  C   . LYS E 1 148 ? 180.713 259.525 236.085 1.00 102.33 ? 148 LYS E C   1 
ATOM   12338 O  O   . LYS E 1 148 ? 179.658 258.882 236.085 1.00 103.24 ? 148 LYS E O   1 
ATOM   12339 C  CB  . LYS E 1 148 ? 180.474 261.870 235.252 1.00 105.23 ? 148 LYS E CB  1 
ATOM   12340 C  CG  . LYS E 1 148 ? 181.416 261.574 234.097 1.00 105.72 ? 148 LYS E CG  1 
ATOM   12341 C  CD  . LYS E 1 148 ? 181.278 262.608 232.992 1.00 104.37 ? 148 LYS E CD  1 
ATOM   12342 C  CE  . LYS E 1 148 ? 179.820 262.885 232.669 1.00 102.92 ? 148 LYS E CE  1 
ATOM   12343 N  NZ  . LYS E 1 148 ? 179.634 264.244 232.090 1.00 98.40  ? 148 LYS E NZ  1 
ATOM   12344 N  N   . ARG E 1 149 ? 181.879 258.980 235.742 1.00 101.39 ? 149 ARG E N   1 
ATOM   12345 C  CA  . ARG E 1 149 ? 181.993 257.617 235.241 1.00 102.05 ? 149 ARG E CA  1 
ATOM   12346 C  C   . ARG E 1 149 ? 182.400 256.609 236.308 1.00 100.13 ? 149 ARG E C   1 
ATOM   12347 O  O   . ARG E 1 149 ? 182.586 255.432 235.987 1.00 100.18 ? 149 ARG E O   1 
ATOM   12348 C  CB  . ARG E 1 149 ? 182.996 257.567 234.084 1.00 98.70  ? 149 ARG E CB  1 
ATOM   12349 C  CG  . ARG E 1 149 ? 182.484 258.173 232.789 1.00 99.18  ? 149 ARG E CG  1 
ATOM   12350 C  CD  . ARG E 1 149 ? 181.670 257.165 231.997 1.00 102.30 ? 149 ARG E CD  1 
ATOM   12351 N  NE  . ARG E 1 149 ? 182.264 255.834 232.038 1.00 106.85 ? 149 ARG E NE  1 
ATOM   12352 C  CZ  . ARG E 1 149 ? 181.594 254.724 232.319 1.00 104.74 ? 149 ARG E CZ  1 
ATOM   12353 N  NH1 . ARG E 1 149 ? 180.299 254.747 232.586 1.00 102.71 ? 149 ARG E NH1 1 
ATOM   12354 N  NH2 . ARG E 1 149 ? 182.241 253.562 232.334 1.00 99.06  ? 149 ARG E NH2 1 
ATOM   12355 N  N   . ALA E 1 150 ? 182.541 257.031 237.560 1.00 97.94  ? 150 ALA E N   1 
ATOM   12356 C  CA  . ALA E 1 150 ? 182.988 256.155 238.631 1.00 96.45  ? 150 ALA E CA  1 
ATOM   12357 C  C   . ALA E 1 150 ? 181.799 255.608 239.410 1.00 92.89  ? 150 ALA E C   1 
ATOM   12358 O  O   . ALA E 1 150 ? 180.762 256.264 239.542 1.00 91.07  ? 150 ALA E O   1 
ATOM   12359 C  CB  . ALA E 1 150 ? 183.941 256.887 239.578 1.00 90.67  ? 150 ALA E CB  1 
ATOM   12360 N  N   . THR E 1 151 ? 181.960 254.395 239.925 1.00 90.61  ? 151 THR E N   1 
ATOM   12361 C  CA  . THR E 1 151 ? 180.889 253.715 240.640 1.00 87.83  ? 151 THR E CA  1 
ATOM   12362 C  C   . THR E 1 151 ? 180.721 254.335 242.027 1.00 85.19  ? 151 THR E C   1 
ATOM   12363 O  O   . THR E 1 151 ? 181.381 255.311 242.394 1.00 86.02  ? 151 THR E O   1 
ATOM   12364 C  CB  . THR E 1 151 ? 181.169 252.218 240.715 1.00 91.87  ? 151 THR E CB  1 
ATOM   12365 O  OG1 . THR E 1 151 ? 181.998 251.939 241.851 1.00 91.73  ? 151 THR E OG1 1 
ATOM   12366 C  CG2 . THR E 1 151 ? 181.873 251.746 239.453 1.00 83.81  ? 151 THR E CG2 1 
ATOM   12367 N  N   . GLU E 1 152 ? 179.817 253.756 242.820 1.00 87.64  ? 152 GLU E N   1 
ATOM   12368 C  CA  . GLU E 1 152 ? 179.514 254.310 244.135 1.00 89.62  ? 152 GLU E CA  1 
ATOM   12369 C  C   . GLU E 1 152 ? 180.723 254.238 245.060 1.00 87.77  ? 152 GLU E C   1 
ATOM   12370 O  O   . GLU E 1 152 ? 181.069 255.222 245.727 1.00 88.94  ? 152 GLU E O   1 
ATOM   12371 C  CB  . GLU E 1 152 ? 178.327 253.568 244.745 1.00 94.33  ? 152 GLU E CB  1 
ATOM   12372 C  CG  . GLU E 1 152 ? 178.408 253.397 246.248 1.00 95.24  ? 152 GLU E CG  1 
ATOM   12373 C  CD  . GLU E 1 152 ? 177.047 253.213 246.881 1.00 101.18 ? 152 GLU E CD  1 
ATOM   12374 O  OE1 . GLU E 1 152 ? 176.054 253.112 246.132 1.00 97.72  ? 152 GLU E OE1 1 
ATOM   12375 O  OE2 . GLU E 1 152 ? 176.970 253.168 248.127 1.00 105.72 ? 152 GLU E OE2 1 
ATOM   12376 N  N   . GLU E 1 153 ? 181.378 253.076 245.116 1.00 86.14  ? 153 GLU E N   1 
ATOM   12377 C  CA  . GLU E 1 153 ? 182.543 252.928 245.981 1.00 83.20  ? 153 GLU E CA  1 
ATOM   12378 C  C   . GLU E 1 153 ? 183.679 253.835 245.532 1.00 79.73  ? 153 GLU E C   1 
ATOM   12379 O  O   . GLU E 1 153 ? 184.374 254.433 246.362 1.00 76.34  ? 153 GLU E O   1 
ATOM   12380 C  CB  . GLU E 1 153 ? 182.993 251.468 246.007 1.00 85.62  ? 153 GLU E CB  1 
ATOM   12381 C  CG  . GLU E 1 153 ? 182.145 250.578 246.900 1.00 90.18  ? 153 GLU E CG  1 
ATOM   12382 C  CD  . GLU E 1 153 ? 180.873 250.110 246.221 1.00 101.63 ? 153 GLU E CD  1 
ATOM   12383 O  OE1 . GLU E 1 153 ? 180.831 250.098 244.972 1.00 100.78 ? 153 GLU E OE1 1 
ATOM   12384 O  OE2 . GLU E 1 153 ? 179.912 249.755 246.937 1.00 101.04 ? 153 GLU E OE2 1 
ATOM   12385 N  N   . GLU E 1 154 ? 183.888 253.946 244.219 1.00 75.47  ? 154 GLU E N   1 
ATOM   12386 C  CA  . GLU E 1 154 ? 184.918 254.843 243.709 1.00 72.13  ? 154 GLU E CA  1 
ATOM   12387 C  C   . GLU E 1 154 ? 184.606 256.292 244.060 1.00 74.19  ? 154 GLU E C   1 
ATOM   12388 O  O   . GLU E 1 154 ? 185.505 257.060 244.423 1.00 73.65  ? 154 GLU E O   1 
ATOM   12389 C  CB  . GLU E 1 154 ? 185.056 254.666 242.198 1.00 77.30  ? 154 GLU E CB  1 
ATOM   12390 C  CG  . GLU E 1 154 ? 185.370 253.240 241.775 1.00 81.02  ? 154 GLU E CG  1 
ATOM   12391 C  CD  . GLU E 1 154 ? 185.705 253.129 240.302 1.00 88.25  ? 154 GLU E CD  1 
ATOM   12392 O  OE1 . GLU E 1 154 ? 185.202 253.955 239.514 1.00 88.69  ? 154 GLU E OE1 1 
ATOM   12393 O  OE2 . GLU E 1 154 ? 186.473 252.216 239.932 1.00 84.74  ? 154 GLU E OE2 1 
ATOM   12394 N  N   . ILE E 1 155 ? 183.334 256.685 243.957 1.00 75.38  ? 155 ILE E N   1 
ATOM   12395 C  CA  . ILE E 1 155 ? 182.947 258.043 244.328 1.00 70.21  ? 155 ILE E CA  1 
ATOM   12396 C  C   . ILE E 1 155 ? 183.218 258.287 245.806 1.00 69.20  ? 155 ILE E C   1 
ATOM   12397 O  O   . ILE E 1 155 ? 183.710 259.352 246.192 1.00 70.62  ? 155 ILE E O   1 
ATOM   12398 C  CB  . ILE E 1 155 ? 181.470 258.299 243.975 1.00 75.30  ? 155 ILE E CB  1 
ATOM   12399 C  CG1 . ILE E 1 155 ? 181.354 259.014 242.629 1.00 82.59  ? 155 ILE E CG1 1 
ATOM   12400 C  CG2 . ILE E 1 155 ? 180.800 259.119 245.063 1.00 71.57  ? 155 ILE E CG2 1 
ATOM   12401 C  CD1 . ILE E 1 155 ? 181.843 258.199 241.458 1.00 88.03  ? 155 ILE E CD1 1 
ATOM   12402 N  N   . ALA E 1 156 ? 182.892 257.312 246.658 1.00 67.29  ? 156 ALA E N   1 
ATOM   12403 C  CA  . ALA E 1 156 ? 183.160 257.473 248.085 1.00 67.44  ? 156 ALA E CA  1 
ATOM   12404 C  C   . ALA E 1 156 ? 184.654 257.601 248.355 1.00 66.10  ? 156 ALA E C   1 
ATOM   12405 O  O   . ALA E 1 156 ? 185.083 258.446 249.153 1.00 64.25  ? 156 ALA E O   1 
ATOM   12406 C  CB  . ALA E 1 156 ? 182.572 256.298 248.866 1.00 68.76  ? 156 ALA E CB  1 
ATOM   12407 N  N   . ALA E 1 157 ? 185.463 256.771 247.694 1.00 67.61  ? 157 ALA E N   1 
ATOM   12408 C  CA  . ALA E 1 157 ? 186.908 256.845 247.880 1.00 63.39  ? 157 ALA E CA  1 
ATOM   12409 C  C   . ALA E 1 157 ? 187.447 258.202 247.451 1.00 59.75  ? 157 ALA E C   1 
ATOM   12410 O  O   . ALA E 1 157 ? 188.306 258.780 248.127 1.00 59.21  ? 157 ALA E O   1 
ATOM   12411 C  CB  . ALA E 1 157 ? 187.597 255.723 247.105 1.00 61.06  ? 157 ALA E CB  1 
ATOM   12412 N  N   . ILE E 1 158 ? 186.961 258.724 246.325 1.00 59.11  ? 158 ILE E N   1 
ATOM   12413 C  CA  . ILE E 1 158 ? 187.410 260.035 245.863 1.00 55.97  ? 158 ILE E CA  1 
ATOM   12414 C  C   . ILE E 1 158 ? 186.987 261.119 246.847 1.00 57.14  ? 158 ILE E C   1 
ATOM   12415 O  O   . ILE E 1 158 ? 187.773 262.006 247.199 1.00 58.04  ? 158 ILE E O   1 
ATOM   12416 C  CB  . ILE E 1 158 ? 186.882 260.316 244.447 1.00 52.69  ? 158 ILE E CB  1 
ATOM   12417 C  CG1 . ILE E 1 158 ? 187.343 259.220 243.484 1.00 58.15  ? 158 ILE E CG1 1 
ATOM   12418 C  CG2 . ILE E 1 158 ? 187.345 261.680 243.970 1.00 48.37  ? 158 ILE E CG2 1 
ATOM   12419 C  CD1 . ILE E 1 158 ? 187.008 259.495 242.037 1.00 65.18  ? 158 ILE E CD1 1 
ATOM   12420 N  N   . ASN E 1 159 ? 185.736 261.063 247.310 1.00 57.53  ? 159 ASN E N   1 
ATOM   12421 C  CA  . ASN E 1 159 ? 185.219 262.084 248.212 1.00 54.86  ? 159 ASN E CA  1 
ATOM   12422 C  C   . ASN E 1 159 ? 185.873 262.036 249.585 1.00 49.18  ? 159 ASN E C   1 
ATOM   12423 O  O   . ASN E 1 159 ? 185.811 263.028 250.318 1.00 50.01  ? 159 ASN E O   1 
ATOM   12424 C  CB  . ASN E 1 159 ? 183.704 261.936 248.362 1.00 59.81  ? 159 ASN E CB  1 
ATOM   12425 C  CG  . ASN E 1 159 ? 182.968 262.100 247.049 1.00 65.93  ? 159 ASN E CG  1 
ATOM   12426 O  OD1 . ASN E 1 159 ? 183.530 262.577 246.064 1.00 65.64  ? 159 ASN E OD1 1 
ATOM   12427 N  ND2 . ASN E 1 159 ? 181.702 261.700 247.027 1.00 68.67  ? 159 ASN E ND2 1 
ATOM   12428 N  N   . SER E 1 160 ? 186.486 260.909 249.953 1.00 50.55  ? 160 SER E N   1 
ATOM   12429 C  CA  . SER E 1 160 ? 187.096 260.810 251.275 1.00 49.31  ? 160 SER E CA  1 
ATOM   12430 C  C   . SER E 1 160 ? 188.146 261.893 251.506 1.00 47.47  ? 160 SER E C   1 
ATOM   12431 O  O   . SER E 1 160 ? 188.392 262.279 252.654 1.00 46.35  ? 160 SER E O   1 
ATOM   12432 C  CB  . SER E 1 160 ? 187.716 259.425 251.466 1.00 51.87  ? 160 SER E CB  1 
ATOM   12433 O  OG  . SER E 1 160 ? 188.787 259.217 250.564 1.00 53.77  ? 160 SER E OG  1 
ATOM   12434 N  N   . VAL E 1 161 ? 188.769 262.398 250.440 1.00 43.82  ? 161 VAL E N   1 
ATOM   12435 C  CA  . VAL E 1 161 ? 189.835 263.387 250.562 1.00 40.18  ? 161 VAL E CA  1 
ATOM   12436 C  C   . VAL E 1 161 ? 189.321 264.813 250.378 1.00 42.21  ? 161 VAL E C   1 
ATOM   12437 O  O   . VAL E 1 161 ? 190.123 265.743 250.258 1.00 42.12  ? 161 VAL E O   1 
ATOM   12438 C  CB  . VAL E 1 161 ? 190.977 263.094 249.577 1.00 37.60  ? 161 VAL E CB  1 
ATOM   12439 C  CG1 . VAL E 1 161 ? 191.427 261.649 249.703 1.00 43.88  ? 161 VAL E CG1 1 
ATOM   12440 C  CG2 . VAL E 1 161 ? 190.541 263.404 248.157 1.00 38.11  ? 161 VAL E CG2 1 
ATOM   12441 N  N   . TYR E 1 162 ? 188.007 265.006 250.350 1.00 43.81  ? 162 TYR E N   1 
ATOM   12442 C  CA  . TYR E 1 162 ? 187.411 266.323 250.202 1.00 39.36  ? 162 TYR E CA  1 
ATOM   12443 C  C   . TYR E 1 162 ? 186.562 266.655 251.421 1.00 44.68  ? 162 TYR E C   1 
ATOM   12444 O  O   . TYR E 1 162 ? 186.091 265.772 252.141 1.00 44.61  ? 162 TYR E O   1 
ATOM   12445 C  CB  . TYR E 1 162 ? 186.549 266.415 248.938 1.00 41.04  ? 162 TYR E CB  1 
ATOM   12446 C  CG  . TYR E 1 162 ? 187.335 266.474 247.652 1.00 42.57  ? 162 TYR E CG  1 
ATOM   12447 C  CD1 . TYR E 1 162 ? 187.714 267.690 247.104 1.00 43.13  ? 162 TYR E CD1 1 
ATOM   12448 C  CD2 . TYR E 1 162 ? 187.696 265.315 246.983 1.00 43.51  ? 162 TYR E CD2 1 
ATOM   12449 C  CE1 . TYR E 1 162 ? 188.430 267.750 245.927 1.00 41.69  ? 162 TYR E CE1 1 
ATOM   12450 C  CE2 . TYR E 1 162 ? 188.412 265.365 245.806 1.00 43.80  ? 162 TYR E CE2 1 
ATOM   12451 C  CZ  . TYR E 1 162 ? 188.777 266.584 245.283 1.00 45.93  ? 162 TYR E CZ  1 
ATOM   12452 O  OH  . TYR E 1 162 ? 189.491 266.634 244.109 1.00 49.91  ? 162 TYR E OH  1 
ATOM   12453 N  N   . TYR E 1 163 ? 186.375 267.953 251.639 1.00 44.98  ? 163 TYR E N   1 
ATOM   12454 C  CA  . TYR E 1 163 ? 185.546 268.475 252.712 1.00 45.03  ? 163 TYR E CA  1 
ATOM   12455 C  C   . TYR E 1 163 ? 184.649 269.552 252.127 1.00 50.17  ? 163 TYR E C   1 
ATOM   12456 O  O   . TYR E 1 163 ? 185.117 270.416 251.376 1.00 51.48  ? 163 TYR E O   1 
ATOM   12457 C  CB  . TYR E 1 163 ? 186.406 269.037 253.849 1.00 46.78  ? 163 TYR E CB  1 
ATOM   12458 C  CG  . TYR E 1 163 ? 185.712 270.064 254.712 1.00 53.32  ? 163 TYR E CG  1 
ATOM   12459 C  CD1 . TYR E 1 163 ? 184.870 269.677 255.744 1.00 53.46  ? 163 TYR E CD1 1 
ATOM   12460 C  CD2 . TYR E 1 163 ? 185.910 271.422 254.502 1.00 52.82  ? 163 TYR E CD2 1 
ATOM   12461 C  CE1 . TYR E 1 163 ? 184.238 270.611 256.537 1.00 56.17  ? 163 TYR E CE1 1 
ATOM   12462 C  CE2 . TYR E 1 163 ? 185.282 272.364 255.291 1.00 56.06  ? 163 TYR E CE2 1 
ATOM   12463 C  CZ  . TYR E 1 163 ? 184.448 271.953 256.307 1.00 60.96  ? 163 TYR E CZ  1 
ATOM   12464 O  OH  . TYR E 1 163 ? 183.820 272.887 257.097 1.00 67.52  ? 163 TYR E OH  1 
ATOM   12465 N  N   . THR E 1 164 ? 183.363 269.483 252.448 1.00 52.68  ? 164 THR E N   1 
ATOM   12466 C  CA  . THR E 1 164 ? 182.376 270.440 251.972 1.00 53.92  ? 164 THR E CA  1 
ATOM   12467 C  C   . THR E 1 164 ? 181.865 271.252 253.151 1.00 55.19  ? 164 THR E C   1 
ATOM   12468 O  O   . THR E 1 164 ? 181.429 270.685 254.158 1.00 56.22  ? 164 THR E O   1 
ATOM   12469 C  CB  . THR E 1 164 ? 181.215 269.731 251.270 1.00 50.66  ? 164 THR E CB  1 
ATOM   12470 O  OG1 . THR E 1 164 ? 181.718 268.971 250.164 1.00 50.19  ? 164 THR E OG1 1 
ATOM   12471 C  CG2 . THR E 1 164 ? 180.203 270.741 250.762 1.00 49.86  ? 164 THR E CG2 1 
ATOM   12472 N  N   . ASN E 1 165 ? 181.929 272.571 253.029 1.00 54.03  ? 165 ASN E N   1 
ATOM   12473 C  CA  . ASN E 1 165 ? 181.409 273.429 254.080 1.00 50.96  ? 165 ASN E CA  1 
ATOM   12474 C  C   . ASN E 1 165 ? 179.906 273.208 254.217 1.00 53.78  ? 165 ASN E C   1 
ATOM   12475 O  O   . ASN E 1 165 ? 179.174 273.326 253.225 1.00 53.98  ? 165 ASN E O   1 
ATOM   12476 C  CB  . ASN E 1 165 ? 181.704 274.896 253.774 1.00 52.17  ? 165 ASN E CB  1 
ATOM   12477 C  CG  . ASN E 1 165 ? 181.775 275.748 255.023 1.00 50.90  ? 165 ASN E CG  1 
ATOM   12478 O  OD1 . ASN E 1 165 ? 180.789 275.895 255.745 1.00 51.47  ? 165 ASN E OD1 1 
ATOM   12479 N  ND2 . ASN E 1 165 ? 182.946 276.313 255.288 1.00 53.07  ? 165 ASN E ND2 1 
ATOM   12480 N  N   . PRO E 1 166 ? 179.408 272.887 255.411 1.00 52.24  ? 166 PRO E N   1 
ATOM   12481 C  CA  . PRO E 1 166 ? 177.962 272.675 255.565 1.00 50.51  ? 166 PRO E CA  1 
ATOM   12482 C  C   . PRO E 1 166 ? 177.139 273.916 255.280 1.00 50.82  ? 166 PRO E C   1 
ATOM   12483 O  O   . PRO E 1 166 ? 175.932 273.798 255.036 1.00 53.18  ? 166 PRO E O   1 
ATOM   12484 C  CB  . PRO E 1 166 ? 177.826 272.231 257.028 1.00 53.90  ? 166 PRO E CB  1 
ATOM   12485 C  CG  . PRO E 1 166 ? 179.035 272.781 257.701 1.00 51.64  ? 166 PRO E CG  1 
ATOM   12486 C  CD  . PRO E 1 166 ? 180.133 272.741 256.684 1.00 50.06  ? 166 PRO E CD  1 
ATOM   12487 N  N   . VAL E 1 167 ? 177.749 275.100 255.304 1.00 52.40  ? 167 VAL E N   1 
ATOM   12488 C  CA  . VAL E 1 167 ? 177.032 276.350 255.080 1.00 47.74  ? 167 VAL E CA  1 
ATOM   12489 C  C   . VAL E 1 167 ? 177.188 276.788 253.631 1.00 49.88  ? 167 VAL E C   1 
ATOM   12490 O  O   . VAL E 1 167 ? 176.198 276.934 252.905 1.00 54.44  ? 167 VAL E O   1 
ATOM   12491 C  CB  . VAL E 1 167 ? 177.525 277.449 256.038 1.00 40.70  ? 167 VAL E CB  1 
ATOM   12492 C  CG1 . VAL E 1 167 ? 177.052 278.812 255.566 1.00 35.57  ? 167 VAL E CG1 1 
ATOM   12493 C  CG2 . VAL E 1 167 ? 177.051 277.172 257.453 1.00 45.68  ? 167 VAL E CG2 1 
ATOM   12494 N  N   . THR E 1 168 ? 178.430 277.000 253.197 1.00 49.49  ? 168 THR E N   1 
ATOM   12495 C  CA  . THR E 1 168 ? 178.685 277.530 251.864 1.00 53.36  ? 168 THR E CA  1 
ATOM   12496 C  C   . THR E 1 168 ? 178.694 276.457 250.783 1.00 57.79  ? 168 THR E C   1 
ATOM   12497 O  O   . THR E 1 168 ? 178.685 276.801 249.597 1.00 60.29  ? 168 THR E O   1 
ATOM   12498 C  CB  . THR E 1 168 ? 180.015 278.288 251.844 1.00 56.27  ? 168 THR E CB  1 
ATOM   12499 O  OG1 . THR E 1 168 ? 181.082 277.383 251.539 1.00 60.79  ? 168 THR E OG1 1 
ATOM   12500 C  CG2 . THR E 1 168 ? 180.276 278.936 253.196 1.00 47.20  ? 168 THR E CG2 1 
ATOM   12501 N  N   . HIS E 1 169 ? 178.708 275.178 251.157 1.00 58.66  ? 169 HIS E N   1 
ATOM   12502 C  CA  . HIS E 1 169 ? 178.642 274.079 250.194 1.00 57.88  ? 169 HIS E CA  1 
ATOM   12503 C  C   . HIS E 1 169 ? 179.802 274.128 249.203 1.00 58.11  ? 169 HIS E C   1 
ATOM   12504 O  O   . HIS E 1 169 ? 179.654 273.785 248.028 1.00 61.43  ? 169 HIS E O   1 
ATOM   12505 C  CB  . HIS E 1 169 ? 177.302 274.077 249.456 1.00 56.23  ? 169 HIS E CB  1 
ATOM   12506 C  CG  . HIS E 1 169 ? 176.114 274.117 250.364 1.00 59.71  ? 169 HIS E CG  1 
ATOM   12507 N  ND1 . HIS E 1 169 ? 176.009 273.324 251.485 1.00 60.78  ? 169 HIS E ND1 1 
ATOM   12508 C  CD2 . HIS E 1 169 ? 174.981 274.857 250.318 1.00 62.44  ? 169 HIS E CD2 1 
ATOM   12509 C  CE1 . HIS E 1 169 ? 174.862 273.573 252.092 1.00 65.14  ? 169 HIS E CE1 1 
ATOM   12510 N  NE2 . HIS E 1 169 ? 174.219 274.499 251.404 1.00 65.76  ? 169 HIS E NE2 1 
ATOM   12511 N  N   . ASP E 1 170 ? 180.968 274.557 249.674 1.00 57.68  ? 170 ASP E N   1 
ATOM   12512 C  CA  . ASP E 1 170 ? 182.169 274.606 248.852 1.00 56.97  ? 170 ASP E CA  1 
ATOM   12513 C  C   . ASP E 1 170 ? 183.023 273.374 249.118 1.00 57.32  ? 170 ASP E C   1 
ATOM   12514 O  O   . ASP E 1 170 ? 183.371 273.088 250.268 1.00 58.29  ? 170 ASP E O   1 
ATOM   12515 C  CB  . ASP E 1 170 ? 182.972 275.879 249.122 1.00 58.86  ? 170 ASP E CB  1 
ATOM   12516 C  CG  . ASP E 1 170 ? 182.819 276.906 248.017 1.00 72.08  ? 170 ASP E CG  1 
ATOM   12517 O  OD1 . ASP E 1 170 ? 181.741 277.529 247.926 1.00 75.60  ? 170 ASP E OD1 1 
ATOM   12518 O  OD2 . ASP E 1 170 ? 183.777 277.087 247.236 1.00 75.89  ? 170 ASP E OD2 1 
ATOM   12519 N  N   . ARG E 1 171 ? 183.353 272.652 248.052 1.00 53.47  ? 171 ARG E N   1 
ATOM   12520 C  CA  . ARG E 1 171 ? 184.133 271.426 248.141 1.00 49.11  ? 171 ARG E CA  1 
ATOM   12521 C  C   . ARG E 1 171 ? 185.609 271.752 247.948 1.00 50.31  ? 171 ARG E C   1 
ATOM   12522 O  O   . ARG E 1 171 ? 186.013 272.203 246.870 1.00 49.64  ? 171 ARG E O   1 
ATOM   12523 C  CB  . ARG E 1 171 ? 183.657 270.422 247.091 1.00 49.99  ? 171 ARG E CB  1 
ATOM   12524 C  CG  . ARG E 1 171 ? 184.138 268.998 247.300 1.00 49.03  ? 171 ARG E CG  1 
ATOM   12525 C  CD  . ARG E 1 171 ? 183.245 268.021 246.554 1.00 49.36  ? 171 ARG E CD  1 
ATOM   12526 N  NE  . ARG E 1 171 ? 183.927 266.777 246.222 1.00 52.93  ? 171 ARG E NE  1 
ATOM   12527 C  CZ  . ARG E 1 171 ? 184.737 266.620 245.184 1.00 55.18  ? 171 ARG E CZ  1 
ATOM   12528 N  NH1 . ARG E 1 171 ? 184.999 267.616 244.355 1.00 50.49  ? 171 ARG E NH1 1 
ATOM   12529 N  NH2 . ARG E 1 171 ? 185.296 265.432 244.972 1.00 58.61  ? 171 ARG E NH2 1 
ATOM   12530 N  N   . LYS E 1 172 ? 186.411 271.527 248.985 1.00 49.98  ? 172 LYS E N   1 
ATOM   12531 C  CA  . LYS E 1 172 ? 187.842 271.780 248.922 1.00 44.71  ? 172 LYS E CA  1 
ATOM   12532 C  C   . LYS E 1 172 ? 188.596 270.596 249.505 1.00 44.98  ? 172 LYS E C   1 
ATOM   12533 O  O   . LYS E 1 172 ? 188.078 269.868 250.352 1.00 46.91  ? 172 LYS E O   1 
ATOM   12534 C  CB  . LYS E 1 172 ? 188.224 273.061 249.676 1.00 42.89  ? 172 LYS E CB  1 
ATOM   12535 C  CG  . LYS E 1 172 ? 187.625 274.328 249.091 1.00 50.33  ? 172 LYS E CG  1 
ATOM   12536 C  CD  . LYS E 1 172 ? 187.560 275.438 250.127 1.00 54.24  ? 172 LYS E CD  1 
ATOM   12537 C  CE  . LYS E 1 172 ? 188.937 276.022 250.396 1.00 55.23  ? 172 LYS E CE  1 
ATOM   12538 N  NZ  . LYS E 1 172 ? 189.397 276.909 249.293 1.00 53.61  ? 172 LYS E NZ  1 
ATOM   12539 N  N   . LEU E 1 173 ? 189.831 270.412 249.050 1.00 41.90  ? 173 LEU E N   1 
ATOM   12540 C  CA  . LEU E 1 173 ? 190.656 269.340 249.587 1.00 39.46  ? 173 LEU E CA  1 
ATOM   12541 C  C   . LEU E 1 173 ? 190.773 269.485 251.098 1.00 40.07  ? 173 LEU E C   1 
ATOM   12542 O  O   . LEU E 1 173 ? 191.062 270.570 251.609 1.00 42.48  ? 173 LEU E O   1 
ATOM   12543 C  CB  . LEU E 1 173 ? 192.040 269.365 248.944 1.00 38.55  ? 173 LEU E CB  1 
ATOM   12544 C  CG  . LEU E 1 173 ? 192.145 268.800 247.529 1.00 35.56  ? 173 LEU E CG  1 
ATOM   12545 C  CD1 . LEU E 1 173 ? 193.545 269.016 246.988 1.00 30.28  ? 173 LEU E CD1 1 
ATOM   12546 C  CD2 . LEU E 1 173 ? 191.774 267.328 247.505 1.00 34.97  ? 173 LEU E CD2 1 
ATOM   12547 N  N   . ASN E 1 174 ? 190.551 268.393 251.809 1.00 39.47  ? 174 ASN E N   1 
ATOM   12548 C  CA  . ASN E 1 174 ? 190.602 268.433 253.264 1.00 39.53  ? 174 ASN E CA  1 
ATOM   12549 C  C   . ASN E 1 174 ? 192.050 268.553 253.720 1.00 43.15  ? 174 ASN E C   1 
ATOM   12550 O  O   . ASN E 1 174 ? 192.848 267.642 253.463 1.00 42.77  ? 174 ASN E O   1 
ATOM   12551 C  CB  . ASN E 1 174 ? 189.957 267.180 253.845 1.00 41.28  ? 174 ASN E CB  1 
ATOM   12552 C  CG  . ASN E 1 174 ? 189.815 267.240 255.352 1.00 42.22  ? 174 ASN E CG  1 
ATOM   12553 O  OD1 . ASN E 1 174 ? 190.457 268.049 256.019 1.00 41.12  ? 174 ASN E OD1 1 
ATOM   12554 N  ND2 . ASN E 1 174 ? 188.971 266.374 255.897 1.00 41.86  ? 174 ASN E ND2 1 
ATOM   12555 N  N   . PRO E 1 175 ? 192.434 269.641 254.392 1.00 44.16  ? 175 PRO E N   1 
ATOM   12556 C  CA  . PRO E 1 175 ? 193.838 269.781 254.811 1.00 36.73  ? 175 PRO E CA  1 
ATOM   12557 C  C   . PRO E 1 175 ? 194.295 268.687 255.755 1.00 38.15  ? 175 PRO E C   1 
ATOM   12558 O  O   . PRO E 1 175 ? 195.466 268.290 255.710 1.00 42.86  ? 175 PRO E O   1 
ATOM   12559 C  CB  . PRO E 1 175 ? 193.866 271.160 255.486 1.00 34.10  ? 175 PRO E CB  1 
ATOM   12560 C  CG  . PRO E 1 175 ? 192.665 271.875 254.957 1.00 37.24  ? 175 PRO E CG  1 
ATOM   12561 C  CD  . PRO E 1 175 ? 191.628 270.819 254.745 1.00 42.64  ? 175 PRO E CD  1 
ATOM   12562 N  N   . ASP E 1 176 ? 193.406 268.187 256.615 1.00 41.12  ? 176 ASP E N   1 
ATOM   12563 C  CA  . ASP E 1 176 ? 193.774 267.121 257.536 1.00 42.99  ? 176 ASP E CA  1 
ATOM   12564 C  C   . ASP E 1 176 ? 194.083 265.816 256.816 1.00 45.60  ? 176 ASP E C   1 
ATOM   12565 O  O   . ASP E 1 176 ? 194.704 264.928 257.409 1.00 48.73  ? 176 ASP E O   1 
ATOM   12566 C  CB  . ASP E 1 176 ? 192.657 266.899 258.557 1.00 49.14  ? 176 ASP E CB  1 
ATOM   12567 C  CG  . ASP E 1 176 ? 192.219 268.183 259.232 1.00 58.93  ? 176 ASP E CG  1 
ATOM   12568 O  OD1 . ASP E 1 176 ? 191.596 269.028 258.556 1.00 61.02  ? 176 ASP E OD1 1 
ATOM   12569 O  OD2 . ASP E 1 176 ? 192.492 268.346 260.439 1.00 65.98  ? 176 ASP E OD2 1 
ATOM   12570 N  N   . GLN E 1 177 ? 193.665 265.679 255.558 1.00 40.22  ? 177 GLN E N   1 
ATOM   12571 C  CA  . GLN E 1 177 ? 193.927 264.475 254.785 1.00 39.94  ? 177 GLN E CA  1 
ATOM   12572 C  C   . GLN E 1 177 ? 195.138 264.594 253.872 1.00 36.55  ? 177 GLN E C   1 
ATOM   12573 O  O   . GLN E 1 177 ? 195.648 263.568 253.411 1.00 37.82  ? 177 GLN E O   1 
ATOM   12574 C  CB  . GLN E 1 177 ? 192.702 264.112 253.937 1.00 43.90  ? 177 GLN E CB  1 
ATOM   12575 C  CG  . GLN E 1 177 ? 191.444 263.854 254.742 1.00 39.84  ? 177 GLN E CG  1 
ATOM   12576 C  CD  . GLN E 1 177 ? 191.449 262.493 255.399 1.00 46.46  ? 177 GLN E CD  1 
ATOM   12577 O  OE1 . GLN E 1 177 ? 191.452 261.465 254.724 1.00 50.68  ? 177 GLN E OE1 1 
ATOM   12578 N  NE2 . GLN E 1 177 ? 191.452 262.477 256.727 1.00 45.44  ? 177 GLN E NE2 1 
ATOM   12579 N  N   . MET E 1 178 ? 195.606 265.812 253.599 1.00 34.45  ? 178 MET E N   1 
ATOM   12580 C  CA  . MET E 1 178 ? 196.727 266.033 252.686 1.00 32.78  ? 178 MET E CA  1 
ATOM   12581 C  C   . MET E 1 178 ? 198.028 265.903 253.472 1.00 31.29  ? 178 MET E C   1 
ATOM   12582 O  O   . MET E 1 178 ? 198.646 266.884 253.890 1.00 31.45  ? 178 MET E O   1 
ATOM   12583 C  CB  . MET E 1 178 ? 196.607 267.393 252.011 1.00 30.56  ? 178 MET E CB  1 
ATOM   12584 C  CG  . MET E 1 178 ? 195.406 267.524 251.096 1.00 29.61  ? 178 MET E CG  1 
ATOM   12585 S  SD  . MET E 1 178 ? 195.591 266.582 249.572 1.00 52.54  ? 178 MET E SD  1 
ATOM   12586 C  CE  . MET E 1 178 ? 194.541 265.176 249.914 1.00 32.91  ? 178 MET E CE  1 
ATOM   12587 N  N   . VAL E 1 179 ? 198.447 264.658 253.673 1.00 31.65  ? 179 VAL E N   1 
ATOM   12588 C  CA  . VAL E 1 179 ? 199.645 264.343 254.441 1.00 28.98  ? 179 VAL E CA  1 
ATOM   12589 C  C   . VAL E 1 179 ? 200.597 263.555 253.555 1.00 26.80  ? 179 VAL E C   1 
ATOM   12590 O  O   . VAL E 1 179 ? 200.189 262.592 252.896 1.00 33.75  ? 179 VAL E O   1 
ATOM   12591 C  CB  . VAL E 1 179 ? 199.312 263.562 255.724 1.00 28.42  ? 179 VAL E CB  1 
ATOM   12592 C  CG1 . VAL E 1 179 ? 198.589 264.461 256.710 1.00 25.23  ? 179 VAL E CG1 1 
ATOM   12593 C  CG2 . VAL E 1 179 ? 198.469 262.348 255.396 1.00 35.29  ? 179 VAL E CG2 1 
ATOM   12594 N  N   . TYR E 1 180 ? 201.857 263.971 253.537 1.00 24.65  ? 180 TYR E N   1 
ATOM   12595 C  CA  . TYR E 1 180 ? 202.911 263.316 252.779 1.00 22.70  ? 180 TYR E CA  1 
ATOM   12596 C  C   . TYR E 1 180 ? 203.830 262.575 253.738 1.00 25.56  ? 180 TYR E C   1 
ATOM   12597 O  O   . TYR E 1 180 ? 204.238 263.128 254.764 1.00 22.28  ? 180 TYR E O   1 
ATOM   12598 C  CB  . TYR E 1 180 ? 203.705 264.338 251.963 1.00 22.53  ? 180 TYR E CB  1 
ATOM   12599 C  CG  . TYR E 1 180 ? 204.738 263.737 251.042 1.00 22.68  ? 180 TYR E CG  1 
ATOM   12600 C  CD1 . TYR E 1 180 ? 204.367 262.910 249.993 1.00 24.06  ? 180 TYR E CD1 1 
ATOM   12601 C  CD2 . TYR E 1 180 ? 206.088 264.009 251.215 1.00 20.03  ? 180 TYR E CD2 1 
ATOM   12602 C  CE1 . TYR E 1 180 ? 205.309 262.367 249.146 1.00 21.16  ? 180 TYR E CE1 1 
ATOM   12603 C  CE2 . TYR E 1 180 ? 207.036 263.471 250.375 1.00 19.57  ? 180 TYR E CE2 1 
ATOM   12604 C  CZ  . TYR E 1 180 ? 206.643 262.649 249.344 1.00 23.70  ? 180 TYR E CZ  1 
ATOM   12605 O  OH  . TYR E 1 180 ? 207.588 262.111 248.503 1.00 26.78  ? 180 TYR E OH  1 
ATOM   12606 N  N   . ARG E 1 181 ? 204.142 261.327 253.405 1.00 27.02  ? 181 ARG E N   1 
ATOM   12607 C  CA  . ARG E 1 181 ? 205.048 260.496 254.182 1.00 23.52  ? 181 ARG E CA  1 
ATOM   12608 C  C   . ARG E 1 181 ? 206.372 260.358 253.445 1.00 23.33  ? 181 ARG E C   1 
ATOM   12609 O  O   . ARG E 1 181 ? 206.396 260.172 252.225 1.00 26.31  ? 181 ARG E O   1 
ATOM   12610 C  CB  . ARG E 1 181 ? 204.443 259.112 254.430 1.00 25.06  ? 181 ARG E CB  1 
ATOM   12611 C  CG  . ARG E 1 181 ? 205.177 258.289 255.470 1.00 28.31  ? 181 ARG E CG  1 
ATOM   12612 C  CD  . ARG E 1 181 ? 205.151 256.812 255.117 1.00 30.37  ? 181 ARG E CD  1 
ATOM   12613 N  NE  . ARG E 1 181 ? 205.906 256.531 253.901 1.00 40.93  ? 181 ARG E NE  1 
ATOM   12614 C  CZ  . ARG E 1 181 ? 207.215 256.321 253.862 1.00 45.09  ? 181 ARG E CZ  1 
ATOM   12615 N  NH1 . ARG E 1 181 ? 207.951 256.338 254.961 1.00 40.99  ? 181 ARG E NH1 1 
ATOM   12616 N  NH2 . ARG E 1 181 ? 207.800 256.089 252.691 1.00 43.43  ? 181 ARG E NH2 1 
ATOM   12617 N  N   . TYR E 1 182 ? 207.475 260.452 254.185 1.00 25.81  ? 182 TYR E N   1 
ATOM   12618 C  CA  . TYR E 1 182 ? 208.780 260.311 253.554 1.00 22.86  ? 182 TYR E CA  1 
ATOM   12619 C  C   . TYR E 1 182 ? 209.850 260.059 254.607 1.00 24.33  ? 182 TYR E C   1 
ATOM   12620 O  O   . TYR E 1 182 ? 209.711 260.437 255.773 1.00 25.77  ? 182 TYR E O   1 
ATOM   12621 C  CB  . TYR E 1 182 ? 209.126 261.540 252.705 1.00 22.88  ? 182 TYR E CB  1 
ATOM   12622 C  CG  . TYR E 1 182 ? 209.538 262.757 253.497 1.00 21.96  ? 182 TYR E CG  1 
ATOM   12623 C  CD1 . TYR E 1 182 ? 208.595 263.523 254.167 1.00 18.37  ? 182 TYR E CD1 1 
ATOM   12624 C  CD2 . TYR E 1 182 ? 210.867 263.144 253.571 1.00 18.95  ? 182 TYR E CD2 1 
ATOM   12625 C  CE1 . TYR E 1 182 ? 208.964 264.636 254.889 1.00 17.00  ? 182 TYR E CE1 1 
ATOM   12626 C  CE2 . TYR E 1 182 ? 211.246 264.256 254.292 1.00 17.48  ? 182 TYR E CE2 1 
ATOM   12627 C  CZ  . TYR E 1 182 ? 210.290 264.999 254.949 1.00 17.55  ? 182 TYR E CZ  1 
ATOM   12628 O  OH  . TYR E 1 182 ? 210.662 266.108 255.668 1.00 21.05  ? 182 TYR E OH  1 
ATOM   12629 N  N   . GLU E 1 183 ? 210.932 259.422 254.165 1.00 28.42  ? 183 GLU E N   1 
ATOM   12630 C  CA  . GLU E 1 183 ? 212.052 259.067 255.020 1.00 27.31  ? 183 GLU E CA  1 
ATOM   12631 C  C   . GLU E 1 183 ? 213.339 259.669 254.475 1.00 26.80  ? 183 GLU E C   1 
ATOM   12632 O  O   . GLU E 1 183 ? 213.510 259.824 253.263 1.00 31.66  ? 183 GLU E O   1 
ATOM   12633 C  CB  . GLU E 1 183 ? 212.205 257.549 255.133 1.00 33.01  ? 183 GLU E CB  1 
ATOM   12634 C  CG  . GLU E 1 183 ? 210.984 256.841 255.675 1.00 38.18  ? 183 GLU E CG  1 
ATOM   12635 C  CD  . GLU E 1 183 ? 211.057 255.343 255.480 1.00 52.23  ? 183 GLU E CD  1 
ATOM   12636 O  OE1 . GLU E 1 183 ? 211.662 254.907 254.478 1.00 58.61  ? 183 GLU E OE1 1 
ATOM   12637 O  OE2 . GLU E 1 183 ? 210.520 254.602 256.330 1.00 50.55  ? 183 GLU E OE2 1 
ATOM   12638 N  N   . VAL E 1 184 ? 214.243 260.011 255.388 1.00 28.12  ? 184 VAL E N   1 
ATOM   12639 C  CA  . VAL E 1 184 ? 215.538 260.587 255.049 1.00 26.63  ? 184 VAL E CA  1 
ATOM   12640 C  C   . VAL E 1 184 ? 216.613 259.899 255.878 1.00 28.07  ? 184 VAL E C   1 
ATOM   12641 O  O   . VAL E 1 184 ? 216.439 259.681 257.082 1.00 27.52  ? 184 VAL E O   1 
ATOM   12642 C  CB  . VAL E 1 184 ? 215.568 262.111 255.286 1.00 27.94  ? 184 VAL E CB  1 
ATOM   12643 C  CG1 . VAL E 1 184 ? 216.664 262.752 254.451 1.00 25.92  ? 184 VAL E CG1 1 
ATOM   12644 C  CG2 . VAL E 1 184 ? 214.216 262.725 254.972 1.00 28.87  ? 184 VAL E CG2 1 
ATOM   12645 N  N   . TYR E 1 185 ? 217.728 259.571 255.237 1.00 32.66  ? 185 TYR E N   1 
ATOM   12646 C  CA  . TYR E 1 185 ? 218.859 258.943 255.905 1.00 26.57  ? 185 TYR E CA  1 
ATOM   12647 C  C   . TYR E 1 185 ? 219.884 260.006 256.276 1.00 25.71  ? 185 TYR E C   1 
ATOM   12648 O  O   . TYR E 1 185 ? 220.286 260.810 255.429 1.00 29.94  ? 185 TYR E O   1 
ATOM   12649 C  CB  . TYR E 1 185 ? 219.494 257.882 255.008 1.00 27.10  ? 185 TYR E CB  1 
ATOM   12650 C  CG  . TYR E 1 185 ? 220.502 257.009 255.712 1.00 31.96  ? 185 TYR E CG  1 
ATOM   12651 C  CD1 . TYR E 1 185 ? 220.092 255.960 256.521 1.00 31.21  ? 185 TYR E CD1 1 
ATOM   12652 C  CD2 . TYR E 1 185 ? 221.863 257.234 255.571 1.00 29.04  ? 185 TYR E CD2 1 
ATOM   12653 C  CE1 . TYR E 1 185 ? 221.008 255.158 257.166 1.00 32.08  ? 185 TYR E CE1 1 
ATOM   12654 C  CE2 . TYR E 1 185 ? 222.785 256.438 256.213 1.00 27.57  ? 185 TYR E CE2 1 
ATOM   12655 C  CZ  . TYR E 1 185 ? 222.353 255.401 257.008 1.00 34.09  ? 185 TYR E CZ  1 
ATOM   12656 O  OH  . TYR E 1 185 ? 223.273 254.606 257.648 1.00 38.86  ? 185 TYR E OH  1 
ATOM   12657 N  N   . ASP E 1 186 ? 220.303 260.007 257.540 1.00 29.41  ? 186 ASP E N   1 
ATOM   12658 C  CA  . ASP E 1 186 ? 221.274 260.975 258.051 1.00 29.39  ? 186 ASP E CA  1 
ATOM   12659 C  C   . ASP E 1 186 ? 222.678 260.483 257.716 1.00 28.57  ? 186 ASP E C   1 
ATOM   12660 O  O   . ASP E 1 186 ? 223.329 259.800 258.506 1.00 29.27  ? 186 ASP E O   1 
ATOM   12661 C  CB  . ASP E 1 186 ? 221.096 261.171 259.552 1.00 28.41  ? 186 ASP E CB  1 
ATOM   12662 C  CG  . ASP E 1 186 ? 221.550 262.539 260.022 1.00 37.74  ? 186 ASP E CG  1 
ATOM   12663 O  OD1 . ASP E 1 186 ? 222.309 263.205 259.288 1.00 35.95  ? 186 ASP E OD1 1 
ATOM   12664 O  OD2 . ASP E 1 186 ? 221.149 262.949 261.131 1.00 41.92  ? 186 ASP E OD2 1 
ATOM   12665 N  N   . TYR E 1 187 ? 223.150 260.839 256.520 1.00 25.60  ? 187 TYR E N   1 
ATOM   12666 C  CA  . TYR E 1 187 ? 224.488 260.433 256.100 1.00 24.75  ? 187 TYR E CA  1 
ATOM   12667 C  C   . TYR E 1 187 ? 225.567 261.060 256.974 1.00 27.28  ? 187 TYR E C   1 
ATOM   12668 O  O   . TYR E 1 187 ? 226.536 260.389 257.346 1.00 30.92  ? 187 TYR E O   1 
ATOM   12669 C  CB  . TYR E 1 187 ? 224.712 260.801 254.635 1.00 28.94  ? 187 TYR E CB  1 
ATOM   12670 C  CG  . TYR E 1 187 ? 223.945 259.940 253.665 1.00 30.05  ? 187 TYR E CG  1 
ATOM   12671 C  CD1 . TYR E 1 187 ? 224.387 258.667 253.338 1.00 29.31  ? 187 TYR E CD1 1 
ATOM   12672 C  CD2 . TYR E 1 187 ? 222.776 260.398 253.078 1.00 28.81  ? 187 TYR E CD2 1 
ATOM   12673 C  CE1 . TYR E 1 187 ? 223.687 257.875 252.453 1.00 32.19  ? 187 TYR E CE1 1 
ATOM   12674 C  CE2 . TYR E 1 187 ? 222.069 259.614 252.192 1.00 28.90  ? 187 TYR E CE2 1 
ATOM   12675 C  CZ  . TYR E 1 187 ? 222.529 258.354 251.883 1.00 32.17  ? 187 TYR E CZ  1 
ATOM   12676 O  OH  . TYR E 1 187 ? 221.826 257.570 250.999 1.00 36.87  ? 187 TYR E OH  1 
ATOM   12677 N  N   . ARG E 1 188 ? 225.427 262.346 257.302 1.00 26.88  ? 188 ARG E N   1 
ATOM   12678 C  CA  . ARG E 1 188 ? 226.459 263.020 258.083 1.00 25.71  ? 188 ARG E CA  1 
ATOM   12679 C  C   . ARG E 1 188 ? 226.536 262.466 259.499 1.00 27.52  ? 188 ARG E C   1 
ATOM   12680 O  O   . ARG E 1 188 ? 227.630 262.324 260.057 1.00 30.67  ? 188 ARG E O   1 
ATOM   12681 C  CB  . ARG E 1 188 ? 226.203 264.527 258.110 1.00 25.54  ? 188 ARG E CB  1 
ATOM   12682 C  CG  . ARG E 1 188 ? 227.192 265.303 258.962 1.00 25.85  ? 188 ARG E CG  1 
ATOM   12683 C  CD  . ARG E 1 188 ? 227.268 266.759 258.543 1.00 33.69  ? 188 ARG E CD  1 
ATOM   12684 N  NE  . ARG E 1 188 ? 228.576 267.098 257.993 1.00 38.22  ? 188 ARG E NE  1 
ATOM   12685 C  CZ  . ARG E 1 188 ? 229.596 267.554 258.706 1.00 35.32  ? 188 ARG E CZ  1 
ATOM   12686 N  NH1 . ARG E 1 188 ? 229.498 267.744 260.012 1.00 33.96  ? 188 ARG E NH1 1 
ATOM   12687 N  NH2 . ARG E 1 188 ? 230.746 267.824 258.095 1.00 31.89  ? 188 ARG E NH2 1 
ATOM   12688 N  N   . SER E 1 189 ? 225.387 262.155 260.101 1.00 27.84  ? 189 SER E N   1 
ATOM   12689 C  CA  . SER E 1 189 ? 225.394 261.569 261.436 1.00 26.10  ? 189 SER E CA  1 
ATOM   12690 C  C   . SER E 1 189 ? 225.935 260.146 261.420 1.00 28.24  ? 189 SER E C   1 
ATOM   12691 O  O   . SER E 1 189 ? 226.615 259.732 262.365 1.00 30.20  ? 189 SER E O   1 
ATOM   12692 C  CB  . SER E 1 189 ? 223.986 261.596 262.028 1.00 29.77  ? 189 SER E CB  1 
ATOM   12693 O  OG  . SER E 1 189 ? 223.937 260.896 263.258 1.00 36.14  ? 189 SER E OG  1 
ATOM   12694 N  N   . ALA E 1 190 ? 225.646 259.387 260.362 1.00 26.84  ? 190 ALA E N   1 
ATOM   12695 C  CA  . ALA E 1 190 ? 226.144 258.020 260.274 1.00 22.68  ? 190 ALA E CA  1 
ATOM   12696 C  C   . ALA E 1 190 ? 227.655 257.978 260.087 1.00 25.38  ? 190 ALA E C   1 
ATOM   12697 O  O   . ALA E 1 190 ? 228.300 257.002 260.486 1.00 28.54  ? 190 ALA E O   1 
ATOM   12698 C  CB  . ALA E 1 190 ? 225.446 257.282 259.132 1.00 21.07  ? 190 ALA E CB  1 
ATOM   12699 N  N   . ALA E 1 191 ? 228.235 259.017 259.487 1.00 26.56  ? 191 ALA E N   1 
ATOM   12700 C  CA  . ALA E 1 191 ? 229.670 259.062 259.243 1.00 24.14  ? 191 ALA E CA  1 
ATOM   12701 C  C   . ALA E 1 191 ? 230.468 259.540 260.448 1.00 27.17  ? 191 ALA E C   1 
ATOM   12702 O  O   . ALA E 1 191 ? 231.700 259.462 260.421 1.00 32.74  ? 191 ALA E O   1 
ATOM   12703 C  CB  . ALA E 1 191 ? 229.970 259.962 258.042 1.00 20.99  ? 191 ALA E CB  1 
ATOM   12704 N  N   . LEU E 1 192 ? 229.808 260.027 261.495 1.00 27.50  ? 192 LEU E N   1 
ATOM   12705 C  CA  . LEU E 1 192 ? 230.522 260.528 262.659 1.00 28.62  ? 192 LEU E CA  1 
ATOM   12706 C  C   . LEU E 1 192 ? 231.336 259.419 263.312 1.00 32.34  ? 192 LEU E C   1 
ATOM   12707 O  O   . LEU E 1 192 ? 230.887 258.275 263.419 1.00 40.18  ? 192 LEU E O   1 
ATOM   12708 C  CB  . LEU E 1 192 ? 229.540 261.119 263.669 1.00 30.24  ? 192 LEU E CB  1 
ATOM   12709 C  CG  . LEU E 1 192 ? 229.155 262.586 263.484 1.00 34.99  ? 192 LEU E CG  1 
ATOM   12710 C  CD1 . LEU E 1 192 ? 228.199 263.024 264.580 1.00 36.42  ? 192 LEU E CD1 1 
ATOM   12711 C  CD2 . LEU E 1 192 ? 230.391 263.469 263.461 1.00 33.95  ? 192 LEU E CD2 1 
ATOM   12712 N  N   . ARG E 1 193 ? 232.545 259.768 263.755 1.00 34.36  ? 193 ARG E N   1 
ATOM   12713 C  CA  . ARG E 1 193 ? 233.401 258.783 264.407 1.00 34.73  ? 193 ARG E CA  1 
ATOM   12714 C  C   . ARG E 1 193 ? 232.752 258.249 265.678 1.00 35.74  ? 193 ARG E C   1 
ATOM   12715 O  O   . ARG E 1 193 ? 232.862 257.057 265.987 1.00 40.31  ? 193 ARG E O   1 
ATOM   12716 C  CB  . ARG E 1 193 ? 234.768 259.398 264.706 1.00 33.74  ? 193 ARG E CB  1 
ATOM   12717 C  CG  . ARG E 1 193 ? 235.647 258.561 265.617 1.00 34.49  ? 193 ARG E CG  1 
ATOM   12718 C  CD  . ARG E 1 193 ? 236.263 257.389 264.876 1.00 32.05  ? 193 ARG E CD  1 
ATOM   12719 N  NE  . ARG E 1 193 ? 236.937 257.801 263.652 1.00 31.82  ? 193 ARG E NE  1 
ATOM   12720 C  CZ  . ARG E 1 193 ? 237.154 257.006 262.614 1.00 34.63  ? 193 ARG E CZ  1 
ATOM   12721 N  NH1 . ARG E 1 193 ? 236.760 255.744 262.617 1.00 34.75  ? 193 ARG E NH1 1 
ATOM   12722 N  NH2 . ARG E 1 193 ? 237.785 257.488 261.548 1.00 30.18  ? 193 ARG E NH2 1 
ATOM   12723 N  N   . GLU E 1 194 ? 232.068 259.115 266.426 1.00 37.92  ? 194 GLU E N   1 
ATOM   12724 C  CA  . GLU E 1 194 ? 231.383 258.680 267.637 1.00 36.41  ? 194 GLU E CA  1 
ATOM   12725 C  C   . GLU E 1 194 ? 230.234 257.724 267.341 1.00 37.30  ? 194 GLU E C   1 
ATOM   12726 O  O   . GLU E 1 194 ? 229.814 256.986 268.238 1.00 39.47  ? 194 GLU E O   1 
ATOM   12727 C  CB  . GLU E 1 194 ? 230.849 259.883 268.425 1.00 39.00  ? 194 GLU E CB  1 
ATOM   12728 C  CG  . GLU E 1 194 ? 231.869 260.963 268.822 1.00 48.93  ? 194 GLU E CG  1 
ATOM   12729 C  CD  . GLU E 1 194 ? 232.647 261.551 267.656 1.00 58.64  ? 194 GLU E CD  1 
ATOM   12730 O  OE1 . GLU E 1 194 ? 232.015 262.103 266.730 1.00 54.87  ? 194 GLU E OE1 1 
ATOM   12731 O  OE2 . GLU E 1 194 ? 233.893 261.469 267.671 1.00 58.61  ? 194 GLU E OE2 1 
ATOM   12732 N  N   . HIS E 1 195 ? 229.718 257.721 266.112 1.00 37.20  ? 195 HIS E N   1 
ATOM   12733 C  CA  . HIS E 1 195 ? 228.554 256.925 265.749 1.00 33.52  ? 195 HIS E CA  1 
ATOM   12734 C  C   . HIS E 1 195 ? 228.920 255.666 264.973 1.00 35.08  ? 195 HIS E C   1 
ATOM   12735 O  O   . HIS E 1 195 ? 228.046 255.059 264.346 1.00 38.82  ? 195 HIS E O   1 
ATOM   12736 C  CB  . HIS E 1 195 ? 227.570 257.771 264.942 1.00 31.52  ? 195 HIS E CB  1 
ATOM   12737 C  CG  . HIS E 1 195 ? 226.857 258.806 265.753 1.00 33.11  ? 195 HIS E CG  1 
ATOM   12738 N  ND1 . HIS E 1 195 ? 226.097 259.803 265.183 1.00 32.76  ? 195 HIS E ND1 1 
ATOM   12739 C  CD2 . HIS E 1 195 ? 226.790 258.999 267.091 1.00 33.83  ? 195 HIS E CD2 1 
ATOM   12740 C  CE1 . HIS E 1 195 ? 225.591 260.566 266.135 1.00 32.77  ? 195 HIS E CE1 1 
ATOM   12741 N  NE2 . HIS E 1 195 ? 225.997 260.101 267.302 1.00 34.62  ? 195 HIS E NE2 1 
ATOM   12742 N  N   . GLN E 1 196 ? 230.188 255.267 264.994 1.00 35.54  ? 196 GLN E N   1 
ATOM   12743 C  CA  . GLN E 1 196 ? 230.578 254.021 264.352 1.00 36.89  ? 196 GLN E CA  1 
ATOM   12744 C  C   . GLN E 1 196 ? 229.846 252.851 264.995 1.00 38.31  ? 196 GLN E C   1 
ATOM   12745 O  O   . GLN E 1 196 ? 229.653 252.810 266.212 1.00 41.40  ? 196 GLN E O   1 
ATOM   12746 C  CB  . GLN E 1 196 ? 232.089 253.822 264.452 1.00 36.28  ? 196 GLN E CB  1 
ATOM   12747 C  CG  . GLN E 1 196 ? 232.896 254.710 263.524 1.00 38.87  ? 196 GLN E CG  1 
ATOM   12748 C  CD  . GLN E 1 196 ? 233.304 253.997 262.251 1.00 45.74  ? 196 GLN E CD  1 
ATOM   12749 O  OE1 . GLN E 1 196 ? 233.065 252.801 262.092 1.00 49.25  ? 196 GLN E OE1 1 
ATOM   12750 N  NE2 . GLN E 1 196 ? 233.925 254.730 261.335 1.00 44.04  ? 196 GLN E NE2 1 
ATOM   12751 N  N   . LEU E 1 197 ? 229.429 251.893 264.167 1.00 40.37  ? 197 LEU E N   1 
ATOM   12752 C  CA  . LEU E 1 197 ? 228.679 250.755 264.679 1.00 37.35  ? 197 LEU E CA  1 
ATOM   12753 C  C   . LEU E 1 197 ? 229.548 249.781 265.462 1.00 40.96  ? 197 LEU E C   1 
ATOM   12754 O  O   . LEU E 1 197 ? 229.006 248.893 266.126 1.00 46.72  ? 197 LEU E O   1 
ATOM   12755 C  CB  . LEU E 1 197 ? 227.981 250.025 263.530 1.00 37.28  ? 197 LEU E CB  1 
ATOM   12756 C  CG  . LEU E 1 197 ? 226.678 250.661 263.041 1.00 33.46  ? 197 LEU E CG  1 
ATOM   12757 C  CD1 . LEU E 1 197 ? 225.836 249.649 262.286 1.00 32.68  ? 197 LEU E CD1 1 
ATOM   12758 C  CD2 . LEU E 1 197 ? 225.898 251.242 264.207 1.00 32.29  ? 197 LEU E CD2 1 
ATOM   12759 N  N   . LYS E 1 198 ? 230.868 249.922 265.398 1.00 44.33  ? 198 LYS E N   1 
ATOM   12760 C  CA  . LYS E 1 198 ? 231.794 249.132 266.196 1.00 38.68  ? 198 LYS E CA  1 
ATOM   12761 C  C   . LYS E 1 198 ? 232.458 250.041 267.219 1.00 40.73  ? 198 LYS E C   1 
ATOM   12762 O  O   . LYS E 1 198 ? 232.947 251.120 266.869 1.00 44.44  ? 198 LYS E O   1 
ATOM   12763 C  CB  . LYS E 1 198 ? 232.852 248.464 265.317 1.00 43.75  ? 198 LYS E CB  1 
ATOM   12764 C  CG  . LYS E 1 198 ? 232.368 247.234 264.572 1.00 53.02  ? 198 LYS E CG  1 
ATOM   12765 C  CD  . LYS E 1 198 ? 233.452 246.691 263.656 1.00 54.84  ? 198 LYS E CD  1 
ATOM   12766 C  CE  . LYS E 1 198 ? 233.170 245.252 263.262 1.00 62.98  ? 198 LYS E CE  1 
ATOM   12767 N  NZ  . LYS E 1 198 ? 231.725 244.919 263.386 1.00 65.17  ? 198 LYS E NZ  1 
ATOM   12768 N  N   . ALA E 1 199 ? 232.470 249.610 268.480 1.00 37.31  ? 199 ALA E N   1 
ATOM   12769 C  CA  . ALA E 1 199 ? 233.048 250.443 269.529 1.00 42.91  ? 199 ALA E CA  1 
ATOM   12770 C  C   . ALA E 1 199 ? 234.532 250.682 269.288 1.00 48.97  ? 199 ALA E C   1 
ATOM   12771 O  O   . ALA E 1 199 ? 235.024 251.805 269.455 1.00 48.44  ? 199 ALA E O   1 
ATOM   12772 C  CB  . ALA E 1 199 ? 232.821 249.799 270.895 1.00 41.06  ? 199 ALA E CB  1 
ATOM   12773 N  N   . ALA E 1 200 ? 235.261 249.640 268.883 1.00 48.06  ? 200 ALA E N   1 
ATOM   12774 C  CA  . ALA E 1 200 ? 236.699 249.775 268.680 1.00 45.86  ? 200 ALA E CA  1 
ATOM   12775 C  C   . ALA E 1 200 ? 237.025 250.821 267.625 1.00 47.45  ? 200 ALA E C   1 
ATOM   12776 O  O   . ALA E 1 200 ? 238.115 251.404 267.646 1.00 49.51  ? 200 ALA E O   1 
ATOM   12777 C  CB  . ALA E 1 200 ? 237.302 248.425 268.294 1.00 44.24  ? 200 ALA E CB  1 
ATOM   12778 N  N   . LYS E 1 201 ? 236.104 251.073 266.701 1.00 45.51  ? 201 LYS E N   1 
ATOM   12779 C  CA  . LYS E 1 201 ? 236.320 252.038 265.633 1.00 39.32  ? 201 LYS E CA  1 
ATOM   12780 C  C   . LYS E 1 201 ? 235.902 253.450 266.015 1.00 40.15  ? 201 LYS E C   1 
ATOM   12781 O  O   . LYS E 1 201 ? 235.979 254.349 265.173 1.00 41.74  ? 201 LYS E O   1 
ATOM   12782 C  CB  . LYS E 1 201 ? 235.566 251.604 264.374 1.00 39.25  ? 201 LYS E CB  1 
ATOM   12783 C  CG  . LYS E 1 201 ? 235.833 250.172 263.954 1.00 45.79  ? 201 LYS E CG  1 
ATOM   12784 C  CD  . LYS E 1 201 ? 235.846 250.041 262.442 1.00 56.39  ? 201 LYS E CD  1 
ATOM   12785 C  CE  . LYS E 1 201 ? 236.419 251.287 261.785 1.00 54.46  ? 201 LYS E CE  1 
ATOM   12786 N  NZ  . LYS E 1 201 ? 236.551 251.130 260.311 1.00 55.36  ? 201 LYS E NZ  1 
ATOM   12787 N  N   . ARG E 1 202 ? 235.465 253.670 267.254 1.00 38.61  ? 202 ARG E N   1 
ATOM   12788 C  CA  . ARG E 1 202 ? 235.016 254.985 267.685 1.00 33.70  ? 202 ARG E CA  1 
ATOM   12789 C  C   . ARG E 1 202 ? 236.133 255.849 268.252 1.00 34.49  ? 202 ARG E C   1 
ATOM   12790 O  O   . ARG E 1 202 ? 235.896 257.028 268.535 1.00 38.01  ? 202 ARG E O   1 
ATOM   12791 C  CB  . ARG E 1 202 ? 233.902 254.844 268.726 1.00 31.69  ? 202 ARG E CB  1 
ATOM   12792 C  CG  . ARG E 1 202 ? 232.627 254.244 268.171 1.00 34.87  ? 202 ARG E CG  1 
ATOM   12793 C  CD  . ARG E 1 202 ? 231.581 254.051 269.249 1.00 34.11  ? 202 ARG E CD  1 
ATOM   12794 N  NE  . ARG E 1 202 ? 230.485 253.216 268.775 1.00 34.29  ? 202 ARG E NE  1 
ATOM   12795 C  CZ  . ARG E 1 202 ? 229.793 252.380 269.537 1.00 37.49  ? 202 ARG E CZ  1 
ATOM   12796 N  NH1 . ARG E 1 202 ? 230.052 252.245 270.826 1.00 33.53  ? 202 ARG E NH1 1 
ATOM   12797 N  NH2 . ARG E 1 202 ? 228.818 251.661 268.990 1.00 41.95  ? 202 ARG E NH2 1 
ATOM   12798 N  N   . ASN E 1 203 ? 237.333 255.303 268.422 1.00 36.30  ? 203 ASN E N   1 
ATOM   12799 C  CA  . ASN E 1 203 ? 238.452 256.066 268.963 1.00 35.80  ? 203 ASN E CA  1 
ATOM   12800 C  C   . ASN E 1 203 ? 239.740 255.495 268.394 1.00 38.76  ? 203 ASN E C   1 
ATOM   12801 O  O   . ASN E 1 203 ? 240.046 254.319 268.615 1.00 43.42  ? 203 ASN E O   1 
ATOM   12802 C  CB  . ASN E 1 203 ? 238.465 256.015 270.491 1.00 39.98  ? 203 ASN E CB  1 
ATOM   12803 C  CG  . ASN E 1 203 ? 239.682 256.691 271.087 1.00 48.40  ? 203 ASN E CG  1 
ATOM   12804 O  OD1 . ASN E 1 203 ? 240.518 256.046 271.718 1.00 52.92  ? 203 ASN E OD1 1 
ATOM   12805 N  ND2 . ASN E 1 203 ? 239.786 257.999 270.890 1.00 45.89  ? 203 ASN E ND2 1 
ATOM   12806 N  N   . LEU E 1 204 ? 240.489 256.321 267.666 1.00 41.13  ? 204 LEU E N   1 
ATOM   12807 C  CA  . LEU E 1 204 ? 241.726 255.883 267.034 1.00 35.54  ? 204 LEU E CA  1 
ATOM   12808 C  C   . LEU E 1 204 ? 242.939 255.977 267.950 1.00 35.88  ? 204 LEU E C   1 
ATOM   12809 O  O   . LEU E 1 204 ? 243.979 255.390 267.632 1.00 38.47  ? 204 LEU E O   1 
ATOM   12810 C  CB  . LEU E 1 204 ? 241.982 256.696 265.760 1.00 34.84  ? 204 LEU E CB  1 
ATOM   12811 C  CG  . LEU E 1 204 ? 241.005 256.453 264.608 1.00 37.92  ? 204 LEU E CG  1 
ATOM   12812 C  CD1 . LEU E 1 204 ? 241.435 257.217 263.368 1.00 33.64  ? 204 LEU E CD1 1 
ATOM   12813 C  CD2 . LEU E 1 204 ? 240.890 254.970 264.310 1.00 35.59  ? 204 LEU E CD2 1 
ATOM   12814 N  N   . ASN E 1 205 ? 242.837 256.685 269.071 1.00 37.47  ? 205 ASN E N   1 
ATOM   12815 C  CA  . ASN E 1 205 ? 243.944 256.778 270.017 1.00 35.09  ? 205 ASN E CA  1 
ATOM   12816 C  C   . ASN E 1 205 ? 244.151 255.418 270.673 1.00 36.31  ? 205 ASN E C   1 
ATOM   12817 O  O   . ASN E 1 205 ? 243.283 254.937 271.409 1.00 42.25  ? 205 ASN E O   1 
ATOM   12818 C  CB  . ASN E 1 205 ? 243.657 257.859 271.055 1.00 32.31  ? 205 ASN E CB  1 
ATOM   12819 C  CG  . ASN E 1 205 ? 244.813 258.077 272.014 1.00 34.65  ? 205 ASN E CG  1 
ATOM   12820 O  OD1 . ASN E 1 205 ? 245.594 257.167 272.284 1.00 39.38  ? 205 ASN E OD1 1 
ATOM   12821 N  ND2 . ASN E 1 205 ? 244.925 259.293 272.534 1.00 33.34  ? 205 ASN E ND2 1 
ATOM   12822 N  N   . THR E 1 206 ? 245.301 254.794 270.409 1.00 34.40  ? 206 THR E N   1 
ATOM   12823 C  CA  . THR E 1 206 ? 245.575 253.460 270.930 1.00 38.40  ? 206 THR E CA  1 
ATOM   12824 C  C   . THR E 1 206 ? 245.824 253.448 272.432 1.00 41.25  ? 206 THR E C   1 
ATOM   12825 O  O   . THR E 1 206 ? 245.844 252.366 273.028 1.00 43.77  ? 206 THR E O   1 
ATOM   12826 C  CB  . THR E 1 206 ? 246.777 252.844 270.210 1.00 34.23  ? 206 THR E CB  1 
ATOM   12827 O  OG1 . THR E 1 206 ? 247.987 253.428 270.707 1.00 46.22  ? 206 THR E OG1 1 
ATOM   12828 C  CG2 . THR E 1 206 ? 246.684 253.082 268.712 1.00 28.98  ? 206 THR E CG2 1 
ATOM   12829 N  N   . ASP E 1 207 ? 246.017 254.611 273.056 1.00 39.73  ? 207 ASP E N   1 
ATOM   12830 C  CA  . ASP E 1 207 ? 246.172 254.665 274.504 1.00 41.17  ? 207 ASP E CA  1 
ATOM   12831 C  C   . ASP E 1 207 ? 244.860 254.422 275.235 1.00 47.34  ? 207 ASP E C   1 
ATOM   12832 O  O   . ASP E 1 207 ? 244.880 254.089 276.424 1.00 52.63  ? 207 ASP E O   1 
ATOM   12833 C  CB  . ASP E 1 207 ? 246.746 256.017 274.926 1.00 40.36  ? 207 ASP E CB  1 
ATOM   12834 C  CG  . ASP E 1 207 ? 248.221 256.148 274.617 1.00 42.78  ? 207 ASP E CG  1 
ATOM   12835 O  OD1 . ASP E 1 207 ? 248.816 255.167 274.128 1.00 42.95  ? 207 ASP E OD1 1 
ATOM   12836 O  OD2 . ASP E 1 207 ? 248.785 257.234 274.864 1.00 40.05  ? 207 ASP E OD2 1 
ATOM   12837 N  N   . ILE E 1 208 ? 243.729 254.582 274.556 1.00 48.45  ? 208 ILE E N   1 
ATOM   12838 C  CA  . ILE E 1 208 ? 242.411 254.475 275.168 1.00 50.25  ? 208 ILE E CA  1 
ATOM   12839 C  C   . ILE E 1 208 ? 241.829 253.109 274.839 1.00 54.70  ? 208 ILE E C   1 
ATOM   12840 O  O   . ILE E 1 208 ? 241.830 252.687 273.676 1.00 57.40  ? 208 ILE E O   1 
ATOM   12841 C  CB  . ILE E 1 208 ? 241.484 255.602 274.685 1.00 47.93  ? 208 ILE E CB  1 
ATOM   12842 C  CG1 . ILE E 1 208 ? 241.892 256.933 275.320 1.00 46.13  ? 208 ILE E CG1 1 
ATOM   12843 C  CG2 . ILE E 1 208 ? 240.035 255.276 275.000 1.00 48.18  ? 208 ILE E CG2 1 
ATOM   12844 C  CD1 . ILE E 1 208 ? 241.893 258.095 274.356 1.00 47.11  ? 208 ILE E CD1 1 
ATOM   12845 N  N   . LYS E 1 209 ? 241.340 252.415 275.861 1.00 60.59  ? 209 LYS E N   1 
ATOM   12846 C  CA  . LYS E 1 209 ? 240.740 251.102 275.687 1.00 70.14  ? 209 LYS E CA  1 
ATOM   12847 C  C   . LYS E 1 209 ? 239.242 251.231 275.440 1.00 73.32  ? 209 LYS E C   1 
ATOM   12848 O  O   . LYS E 1 209 ? 238.602 252.197 275.862 1.00 70.34  ? 209 LYS E O   1 
ATOM   12849 C  CB  . LYS E 1 209 ? 240.992 250.223 276.913 1.00 68.63  ? 209 LYS E CB  1 
ATOM   12850 C  CG  . LYS E 1 209 ? 241.989 249.100 276.676 1.00 68.02  ? 209 LYS E CG  1 
ATOM   12851 C  CD  . LYS E 1 209 ? 243.188 249.587 275.878 1.00 65.78  ? 209 LYS E CD  1 
ATOM   12852 C  CE  . LYS E 1 209 ? 244.054 250.528 276.699 1.00 65.36  ? 209 LYS E CE  1 
ATOM   12853 N  NZ  . LYS E 1 209 ? 245.123 251.161 275.877 1.00 57.38  ? 209 LYS E NZ  1 
ATOM   12854 N  N   . VAL E 1 210 ? 238.690 250.241 274.747 1.00 74.42  ? 210 VAL E N   1 
ATOM   12855 C  CA  . VAL E 1 210 ? 237.265 250.224 274.432 1.00 82.01  ? 210 VAL E CA  1 
ATOM   12856 C  C   . VAL E 1 210 ? 236.509 249.636 275.616 1.00 86.92  ? 210 VAL E C   1 
ATOM   12857 O  O   . VAL E 1 210 ? 236.766 248.500 276.028 1.00 89.58  ? 210 VAL E O   1 
ATOM   12858 C  CB  . VAL E 1 210 ? 236.993 249.427 273.149 1.00 77.06  ? 210 VAL E CB  1 
ATOM   12859 C  CG1 . VAL E 1 210 ? 235.501 249.201 272.974 1.00 75.29  ? 210 VAL E CG1 1 
ATOM   12860 C  CG2 . VAL E 1 210 ? 237.574 250.150 271.944 1.00 70.50  ? 210 VAL E CG2 1 
ATOM   12861 N  N   . ASP E 1 211 ? 235.575 250.409 276.164 1.00 89.09  ? 211 ASP E N   1 
ATOM   12862 C  CA  . ASP E 1 211 ? 234.802 249.969 277.318 1.00 93.74  ? 211 ASP E CA  1 
ATOM   12863 C  C   . ASP E 1 211 ? 233.511 249.313 276.851 1.00 95.34  ? 211 ASP E C   1 
ATOM   12864 O  O   . ASP E 1 211 ? 232.690 249.980 276.207 1.00 94.83  ? 211 ASP E O   1 
ATOM   12865 C  CB  . ASP E 1 211 ? 234.489 251.141 278.233 1.00 96.23  ? 211 ASP E CB  1 
ATOM   12866 C  CG  . ASP E 1 211 ? 235.519 251.314 279.331 1.00 100.64 ? 211 ASP E CG  1 
ATOM   12867 O  OD1 . ASP E 1 211 ? 236.707 251.011 279.089 1.00 99.52  ? 211 ASP E OD1 1 
ATOM   12868 O  OD2 . ASP E 1 211 ? 235.141 251.755 280.436 1.00 100.82 ? 211 ASP E OD2 1 
ATOM   12869 N  N   . PRO E 1 212 ? 233.288 248.030 277.143 1.00 98.31  ? 212 PRO E N   1 
ATOM   12870 C  CA  . PRO E 1 212 ? 232.038 247.391 276.703 1.00 100.63 ? 212 PRO E CA  1 
ATOM   12871 C  C   . PRO E 1 212 ? 230.792 248.053 277.262 1.00 98.25  ? 212 PRO E C   1 
ATOM   12872 O  O   . PRO E 1 212 ? 229.758 248.080 276.583 1.00 88.21  ? 212 PRO E O   1 
ATOM   12873 C  CB  . PRO E 1 212 ? 232.185 245.946 277.206 1.00 98.69  ? 212 PRO E CB  1 
ATOM   12874 C  CG  . PRO E 1 212 ? 233.649 245.763 277.462 1.00 94.43  ? 212 PRO E CG  1 
ATOM   12875 C  CD  . PRO E 1 212 ? 234.166 247.102 277.873 1.00 95.19  ? 212 PRO E CD  1 
ATOM   12876 N  N   . ASN E 1 213 ? 230.858 248.592 278.481 1.00 101.32 ? 213 ASN E N   1 
ATOM   12877 C  CA  . ASN E 1 213 ? 229.693 249.213 279.101 1.00 100.21 ? 213 ASN E CA  1 
ATOM   12878 C  C   . ASN E 1 213 ? 229.334 250.555 278.479 1.00 93.91  ? 213 ASN E C   1 
ATOM   12879 O  O   . ASN E 1 213 ? 228.277 251.105 278.807 1.00 88.45  ? 213 ASN E O   1 
ATOM   12880 C  CB  . ASN E 1 213 ? 229.930 249.392 280.601 1.00 102.64 ? 213 ASN E CB  1 
ATOM   12881 C  CG  . ASN E 1 213 ? 230.395 248.117 281.274 1.00 105.53 ? 213 ASN E CG  1 
ATOM   12882 O  OD1 . ASN E 1 213 ? 231.507 247.646 281.037 1.00 104.74 ? 213 ASN E OD1 1 
ATOM   12883 N  ND2 . ASN E 1 213 ? 229.544 247.551 282.121 1.00 104.69 ? 213 ASN E ND2 1 
ATOM   12884 N  N   . ALA E 1 214 ? 230.176 251.093 277.600 1.00 95.88  ? 214 ALA E N   1 
ATOM   12885 C  CA  . ALA E 1 214 ? 229.894 252.385 276.991 1.00 87.17  ? 214 ALA E CA  1 
ATOM   12886 C  C   . ALA E 1 214 ? 228.793 252.250 275.947 1.00 78.17  ? 214 ALA E C   1 
ATOM   12887 O  O   . ALA E 1 214 ? 228.893 251.436 275.024 1.00 72.09  ? 214 ALA E O   1 
ATOM   12888 C  CB  . ALA E 1 214 ? 231.160 252.959 276.358 1.00 85.88  ? 214 ALA E CB  1 
ATOM   12889 N  N   . VAL E 1 215 ? 227.742 253.052 276.094 1.00 73.12  ? 215 VAL E N   1 
ATOM   12890 C  CA  . VAL E 1 215 ? 226.626 253.074 275.158 1.00 62.70  ? 215 VAL E CA  1 
ATOM   12891 C  C   . VAL E 1 215 ? 226.488 254.486 274.608 1.00 51.65  ? 215 VAL E C   1 
ATOM   12892 O  O   . VAL E 1 215 ? 226.616 255.466 275.349 1.00 54.16  ? 215 VAL E O   1 
ATOM   12893 C  CB  . VAL E 1 215 ? 225.309 252.614 275.818 1.00 58.21  ? 215 VAL E CB  1 
ATOM   12894 C  CG1 . VAL E 1 215 ? 225.583 251.547 276.866 1.00 65.46  ? 215 VAL E CG1 1 
ATOM   12895 C  CG2 . VAL E 1 215 ? 224.562 253.794 276.417 1.00 50.63  ? 215 VAL E CG2 1 
ATOM   12896 N  N   . VAL E 1 216 ? 226.243 254.586 273.307 1.00 49.95  ? 216 VAL E N   1 
ATOM   12897 C  CA  . VAL E 1 216 ? 226.029 255.865 272.642 1.00 46.61  ? 216 VAL E CA  1 
ATOM   12898 C  C   . VAL E 1 216 ? 224.534 256.033 272.417 1.00 41.31  ? 216 VAL E C   1 
ATOM   12899 O  O   . VAL E 1 216 ? 223.905 255.218 271.733 1.00 43.45  ? 216 VAL E O   1 
ATOM   12900 C  CB  . VAL E 1 216 ? 226.801 255.946 271.316 1.00 44.33  ? 216 VAL E CB  1 
ATOM   12901 C  CG1 . VAL E 1 216 ? 226.847 257.379 270.816 1.00 40.84  ? 216 VAL E CG1 1 
ATOM   12902 C  CG2 . VAL E 1 216 ? 228.204 255.392 271.488 1.00 41.21  ? 216 VAL E CG2 1 
ATOM   12903 N  N   . MET E 1 217 ? 223.961 257.085 272.992 1.00 38.14  ? 217 MET E N   1 
ATOM   12904 C  CA  . MET E 1 217 ? 222.548 257.385 272.817 1.00 37.61  ? 217 MET E CA  1 
ATOM   12905 C  C   . MET E 1 217 ? 222.350 258.185 271.538 1.00 37.34  ? 217 MET E C   1 
ATOM   12906 O  O   . MET E 1 217 ? 223.059 259.167 271.296 1.00 42.99  ? 217 MET E O   1 
ATOM   12907 C  CB  . MET E 1 217 ? 222.004 258.160 274.017 1.00 38.47  ? 217 MET E CB  1 
ATOM   12908 C  CG  . MET E 1 217 ? 221.769 257.309 275.251 1.00 41.83  ? 217 MET E CG  1 
ATOM   12909 S  SD  . MET E 1 217 ? 221.270 255.627 274.847 1.00 57.58  ? 217 MET E SD  1 
ATOM   12910 C  CE  . MET E 1 217 ? 219.814 255.451 275.870 1.00 39.74  ? 217 MET E CE  1 
ATOM   12911 N  N   . ILE E 1 218 ? 221.389 257.762 270.721 1.00 35.69  ? 218 ILE E N   1 
ATOM   12912 C  CA  . ILE E 1 218 ? 221.070 258.427 269.467 1.00 36.79  ? 218 ILE E CA  1 
ATOM   12913 C  C   . ILE E 1 218 ? 219.579 258.719 269.438 1.00 35.99  ? 218 ILE E C   1 
ATOM   12914 O  O   . ILE E 1 218 ? 218.769 257.992 270.024 1.00 40.56  ? 218 ILE E O   1 
ATOM   12915 C  CB  . ILE E 1 218 ? 221.480 257.581 268.240 1.00 34.50  ? 218 ILE E CB  1 
ATOM   12916 C  CG1 . ILE E 1 218 ? 220.825 256.201 268.300 1.00 35.29  ? 218 ILE E CG1 1 
ATOM   12917 C  CG2 . ILE E 1 218 ? 222.988 257.446 268.161 1.00 33.97  ? 218 ILE E CG2 1 
ATOM   12918 C  CD1 . ILE E 1 218 ? 219.474 256.140 267.634 1.00 36.32  ? 218 ILE E CD1 1 
ATOM   12919 N  N   . SER E 1 219 ? 219.219 259.783 268.727 1.00 37.39  ? 219 SER E N   1 
ATOM   12920 C  CA  . SER E 1 219 ? 217.837 260.203 268.566 1.00 34.53  ? 219 SER E CA  1 
ATOM   12921 C  C   . SER E 1 219 ? 217.452 260.148 267.095 1.00 30.64  ? 219 SER E C   1 
ATOM   12922 O  O   . SER E 1 219 ? 218.264 260.455 266.217 1.00 30.11  ? 219 SER E O   1 
ATOM   12923 C  CB  . SER E 1 219 ? 217.622 261.618 269.108 1.00 30.51  ? 219 SER E CB  1 
ATOM   12924 O  OG  . SER E 1 219 ? 217.542 261.613 270.521 1.00 34.37  ? 219 SER E OG  1 
ATOM   12925 N  N   . LYS E 1 220 ? 216.213 259.743 266.835 1.00 30.13  ? 220 LYS E N   1 
ATOM   12926 C  CA  . LYS E 1 220 ? 215.692 259.706 265.477 1.00 32.58  ? 220 LYS E CA  1 
ATOM   12927 C  C   . LYS E 1 220 ? 214.216 260.068 265.510 1.00 31.46  ? 220 LYS E C   1 
ATOM   12928 O  O   . LYS E 1 220 ? 213.568 260.011 266.555 1.00 32.56  ? 220 LYS E O   1 
ATOM   12929 C  CB  . LYS E 1 220 ? 215.895 258.334 264.825 1.00 31.29  ? 220 LYS E CB  1 
ATOM   12930 C  CG  . LYS E 1 220 ? 215.030 257.235 265.411 1.00 31.89  ? 220 LYS E CG  1 
ATOM   12931 C  CD  . LYS E 1 220 ? 215.148 255.964 264.598 1.00 35.10  ? 220 LYS E CD  1 
ATOM   12932 C  CE  . LYS E 1 220 ? 213.928 255.758 263.725 1.00 40.16  ? 220 LYS E CE  1 
ATOM   12933 N  NZ  . LYS E 1 220 ? 214.261 255.001 262.488 1.00 40.32  ? 220 LYS E NZ  1 
ATOM   12934 N  N   . ASP E 1 221 ? 213.691 260.454 264.353 1.00 30.71  ? 221 ASP E N   1 
ATOM   12935 C  CA  . ASP E 1 221 ? 212.286 260.813 264.217 1.00 29.79  ? 221 ASP E CA  1 
ATOM   12936 C  C   . ASP E 1 221 ? 211.532 259.667 263.559 1.00 29.68  ? 221 ASP E C   1 
ATOM   12937 O  O   . ASP E 1 221 ? 211.987 259.119 262.550 1.00 31.29  ? 221 ASP E O   1 
ATOM   12938 C  CB  . ASP E 1 221 ? 212.126 262.091 263.392 1.00 28.84  ? 221 ASP E CB  1 
ATOM   12939 C  CG  . ASP E 1 221 ? 212.612 263.324 264.125 1.00 38.32  ? 221 ASP E CG  1 
ATOM   12940 O  OD1 . ASP E 1 221 ? 212.224 263.516 265.296 1.00 41.78  ? 221 ASP E OD1 1 
ATOM   12941 O  OD2 . ASP E 1 221 ? 213.383 264.104 263.528 1.00 37.64  ? 221 ASP E OD2 1 
ATOM   12942 N  N   . THR E 1 222 ? 210.385 259.303 264.129 1.00 30.31  ? 222 THR E N   1 
ATOM   12943 C  CA  . THR E 1 222 ? 209.498 258.335 263.504 1.00 33.45  ? 222 THR E CA  1 
ATOM   12944 C  C   . THR E 1 222 ? 208.071 258.859 263.544 1.00 36.28  ? 222 THR E C   1 
ATOM   12945 O  O   . THR E 1 222 ? 207.703 259.670 264.398 1.00 38.03  ? 222 THR E O   1 
ATOM   12946 C  CB  . THR E 1 222 ? 209.560 256.949 264.170 1.00 38.93  ? 222 THR E CB  1 
ATOM   12947 O  OG1 . THR E 1 222 ? 208.745 256.032 263.423 1.00 44.25  ? 222 THR E OG1 1 
ATOM   12948 C  CG2 . THR E 1 222 ? 209.048 257.022 265.598 1.00 36.59  ? 222 THR E CG2 1 
ATOM   12949 N  N   . ALA E 1 223 ? 207.275 258.395 262.586 1.00 38.64  ? 223 ALA E N   1 
ATOM   12950 C  CA  . ALA E 1 223 ? 205.877 258.775 262.490 1.00 36.99  ? 223 ALA E CA  1 
ATOM   12951 C  C   . ALA E 1 223 ? 205.100 257.617 261.887 1.00 43.03  ? 223 ALA E C   1 
ATOM   12952 O  O   . ALA E 1 223 ? 205.626 256.855 261.072 1.00 45.50  ? 223 ALA E O   1 
ATOM   12953 C  CB  . ALA E 1 223 ? 205.691 260.043 261.648 1.00 30.78  ? 223 ALA E CB  1 
ATOM   12954 N  N   . PHE E 1 224 ? 203.844 257.492 262.297 1.00 46.19  ? 224 PHE E N   1 
ATOM   12955 C  CA  . PHE E 1 224 ? 202.982 256.436 261.783 1.00 48.25  ? 224 PHE E CA  1 
ATOM   12956 C  C   . PHE E 1 224 ? 201.529 256.859 261.949 1.00 50.31  ? 224 PHE E C   1 
ATOM   12957 O  O   . PHE E 1 224 ? 201.226 257.926 262.489 1.00 49.22  ? 224 PHE E O   1 
ATOM   12958 C  CB  . PHE E 1 224 ? 203.257 255.100 262.480 1.00 49.03  ? 224 PHE E CB  1 
ATOM   12959 C  CG  . PHE E 1 224 ? 203.278 255.184 263.977 1.00 48.68  ? 224 PHE E CG  1 
ATOM   12960 C  CD1 . PHE E 1 224 ? 202.101 255.127 264.702 1.00 49.14  ? 224 PHE E CD1 1 
ATOM   12961 C  CD2 . PHE E 1 224 ? 204.475 255.299 264.661 1.00 50.42  ? 224 PHE E CD2 1 
ATOM   12962 C  CE1 . PHE E 1 224 ? 202.117 255.200 266.078 1.00 49.81  ? 224 PHE E CE1 1 
ATOM   12963 C  CE2 . PHE E 1 224 ? 204.497 255.371 266.037 1.00 49.89  ? 224 PHE E CE2 1 
ATOM   12964 C  CZ  . PHE E 1 224 ? 203.316 255.319 266.747 1.00 50.18  ? 224 PHE E CZ  1 
ATOM   12965 N  N   . VAL E 1 225 ? 200.629 256.013 261.461 1.00 57.63  ? 225 VAL E N   1 
ATOM   12966 C  CA  . VAL E 1 225 ? 199.192 256.238 261.548 1.00 63.83  ? 225 VAL E CA  1 
ATOM   12967 C  C   . VAL E 1 225 ? 198.598 255.112 262.381 1.00 67.33  ? 225 VAL E C   1 
ATOM   12968 O  O   . VAL E 1 225 ? 198.674 253.940 261.993 1.00 67.40  ? 225 VAL E O   1 
ATOM   12969 C  CB  . VAL E 1 225 ? 198.538 256.297 260.160 1.00 58.94  ? 225 VAL E CB  1 
ATOM   12970 C  CG1 . VAL E 1 225 ? 197.025 256.284 260.285 1.00 63.51  ? 225 VAL E CG1 1 
ATOM   12971 C  CG2 . VAL E 1 225 ? 199.010 257.525 259.401 1.00 54.35  ? 225 VAL E CG2 1 
ATOM   12972 N  N   . ASP E 1 226 ? 198.013 255.464 263.522 1.00 68.58  ? 226 ASP E N   1 
ATOM   12973 C  CA  . ASP E 1 226 ? 197.382 254.466 264.367 1.00 75.48  ? 226 ASP E CA  1 
ATOM   12974 C  C   . ASP E 1 226 ? 196.060 254.009 263.750 1.00 80.66  ? 226 ASP E C   1 
ATOM   12975 O  O   . ASP E 1 226 ? 195.570 254.572 262.768 1.00 78.60  ? 226 ASP E O   1 
ATOM   12976 C  CB  . ASP E 1 226 ? 197.167 255.013 265.780 1.00 77.26  ? 226 ASP E CB  1 
ATOM   12977 C  CG  . ASP E 1 226 ? 196.238 256.214 265.812 1.00 80.37  ? 226 ASP E CG  1 
ATOM   12978 O  OD1 . ASP E 1 226 ? 195.634 256.541 264.770 1.00 77.83  ? 226 ASP E OD1 1 
ATOM   12979 O  OD2 . ASP E 1 226 ? 196.110 256.833 266.888 1.00 80.60  ? 226 ASP E OD2 1 
ATOM   12980 N  N   . GLU E 1 227 ? 195.484 252.961 264.343 1.00 85.52  ? 227 GLU E N   1 
ATOM   12981 C  CA  . GLU E 1 227 ? 194.212 252.443 263.851 1.00 86.50  ? 227 GLU E CA  1 
ATOM   12982 C  C   . GLU E 1 227 ? 193.139 253.523 263.823 1.00 87.02  ? 227 GLU E C   1 
ATOM   12983 O  O   . GLU E 1 227 ? 192.261 253.504 262.953 1.00 86.40  ? 227 GLU E O   1 
ATOM   12984 C  CB  . GLU E 1 227 ? 193.754 251.263 264.709 1.00 86.12  ? 227 GLU E CB  1 
ATOM   12985 C  CG  . GLU E 1 227 ? 193.359 251.628 266.137 1.00 89.64  ? 227 GLU E CG  1 
ATOM   12986 C  CD  . GLU E 1 227 ? 194.520 252.153 266.960 1.00 88.79  ? 227 GLU E CD  1 
ATOM   12987 O  OE1 . GLU E 1 227 ? 195.620 251.568 266.882 1.00 92.15  ? 227 GLU E OE1 1 
ATOM   12988 O  OE2 . GLU E 1 227 ? 194.331 253.152 267.686 1.00 82.88  ? 227 GLU E OE2 1 
ATOM   12989 N  N   . SER E 1 228 ? 193.191 254.472 264.759 1.00 85.54  ? 228 SER E N   1 
ATOM   12990 C  CA  . SER E 1 228 ? 192.213 255.551 264.797 1.00 82.97  ? 228 SER E CA  1 
ATOM   12991 C  C   . SER E 1 228 ? 192.358 256.525 263.635 1.00 82.35  ? 228 SER E C   1 
ATOM   12992 O  O   . SER E 1 228 ? 191.461 257.349 263.429 1.00 78.65  ? 228 SER E O   1 
ATOM   12993 C  CB  . SER E 1 228 ? 192.322 256.309 266.121 1.00 83.22  ? 228 SER E CB  1 
ATOM   12994 O  OG  . SER E 1 228 ? 192.529 255.419 267.203 1.00 88.58  ? 228 SER E OG  1 
ATOM   12995 N  N   . GLY E 1 229 ? 193.452 256.456 262.880 1.00 81.58  ? 229 GLY E N   1 
ATOM   12996 C  CA  . GLY E 1 229 ? 193.667 257.341 261.756 1.00 76.72  ? 229 GLY E CA  1 
ATOM   12997 C  C   . GLY E 1 229 ? 194.409 258.622 262.068 1.00 76.14  ? 229 GLY E C   1 
ATOM   12998 O  O   . GLY E 1 229 ? 194.553 259.466 261.175 1.00 76.25  ? 229 GLY E O   1 
ATOM   12999 N  N   . ASN E 1 230 ? 194.880 258.799 263.298 1.00 78.77  ? 230 ASN E N   1 
ATOM   13000 C  CA  . ASN E 1 230 ? 195.642 259.979 263.672 1.00 70.04  ? 230 ASN E CA  1 
ATOM   13001 C  C   . ASN E 1 230 ? 197.128 259.757 263.424 1.00 65.63  ? 230 ASN E C   1 
ATOM   13002 O  O   . ASN E 1 230 ? 197.619 258.625 263.434 1.00 65.42  ? 230 ASN E O   1 
ATOM   13003 C  CB  . ASN E 1 230 ? 195.409 260.332 265.141 1.00 69.68  ? 230 ASN E CB  1 
ATOM   13004 C  CG  . ASN E 1 230 ? 193.939 260.440 265.488 1.00 77.62  ? 230 ASN E CG  1 
ATOM   13005 O  OD1 . ASN E 1 230 ? 193.515 260.046 266.574 1.00 79.96  ? 230 ASN E OD1 1 
ATOM   13006 N  ND2 . ASN E 1 230 ? 193.152 260.983 264.566 1.00 78.42  ? 230 ASN E ND2 1 
ATOM   13007 N  N   . ILE E 1 231 ? 197.842 260.854 263.200 1.00 60.04  ? 231 ILE E N   1 
ATOM   13008 C  CA  . ILE E 1 231 ? 199.277 260.812 262.946 1.00 52.20  ? 231 ILE E CA  1 
ATOM   13009 C  C   . ILE E 1 231 ? 200.003 260.893 264.281 1.00 50.46  ? 231 ILE E C   1 
ATOM   13010 O  O   . ILE E 1 231 ? 199.815 261.848 265.042 1.00 53.22  ? 231 ILE E O   1 
ATOM   13011 C  CB  . ILE E 1 231 ? 199.712 261.953 262.014 1.00 50.58  ? 231 ILE E CB  1 
ATOM   13012 C  CG1 . ILE E 1 231 ? 198.951 261.889 260.689 1.00 48.18  ? 231 ILE E CG1 1 
ATOM   13013 C  CG2 . ILE E 1 231 ? 201.213 261.897 261.768 1.00 44.19  ? 231 ILE E CG2 1 
ATOM   13014 C  CD1 . ILE E 1 231 ? 198.579 260.493 260.266 1.00 55.50  ? 231 ILE E CD1 1 
ATOM   13015 N  N   . ILE E 1 232 ? 200.830 259.893 264.568 1.00 46.24  ? 232 ILE E N   1 
ATOM   13016 C  CA  . ILE E 1 232 ? 201.648 259.860 265.774 1.00 47.01  ? 232 ILE E CA  1 
ATOM   13017 C  C   . ILE E 1 232 ? 203.096 260.067 265.354 1.00 39.76  ? 232 ILE E C   1 
ATOM   13018 O  O   . ILE E 1 232 ? 203.654 259.256 264.604 1.00 43.26  ? 232 ILE E O   1 
ATOM   13019 C  CB  . ILE E 1 232 ? 201.478 258.541 266.542 1.00 48.89  ? 232 ILE E CB  1 
ATOM   13020 C  CG1 . ILE E 1 232 ? 199.996 258.247 266.773 1.00 51.00  ? 232 ILE E CG1 1 
ATOM   13021 C  CG2 . ILE E 1 232 ? 202.228 258.592 267.862 1.00 39.35  ? 232 ILE E CG2 1 
ATOM   13022 C  CD1 . ILE E 1 232 ? 199.232 259.403 267.376 1.00 45.93  ? 232 ILE E CD1 1 
ATOM   13023 N  N   . SER E 1 233 ? 203.695 261.155 265.827 1.00 38.62  ? 233 SER E N   1 
ATOM   13024 C  CA  . SER E 1 233 ? 205.093 261.470 265.578 1.00 36.77  ? 233 SER E CA  1 
ATOM   13025 C  C   . SER E 1 233 ? 205.838 261.505 266.903 1.00 38.51  ? 233 SER E C   1 
ATOM   13026 O  O   . SER E 1 233 ? 205.306 261.987 267.908 1.00 41.62  ? 233 SER E O   1 
ATOM   13027 C  CB  . SER E 1 233 ? 205.238 262.815 264.861 1.00 35.28  ? 233 SER E CB  1 
ATOM   13028 O  OG  . SER E 1 233 ? 204.767 262.737 263.528 1.00 45.41  ? 233 SER E OG  1 
ATOM   13029 N  N   . GLU E 1 234 ? 207.066 260.994 266.910 1.00 39.48  ? 234 GLU E N   1 
ATOM   13030 C  CA  . GLU E 1 234 ? 207.854 261.021 268.132 1.00 37.81  ? 234 GLU E CA  1 
ATOM   13031 C  C   . GLU E 1 234 ? 209.338 260.950 267.808 1.00 37.19  ? 234 GLU E C   1 
ATOM   13032 O  O   . GLU E 1 234 ? 209.747 260.594 266.697 1.00 39.73  ? 234 GLU E O   1 
ATOM   13033 C  CB  . GLU E 1 234 ? 207.461 259.885 269.082 1.00 37.78  ? 234 GLU E CB  1 
ATOM   13034 C  CG  . GLU E 1 234 ? 207.929 258.514 268.653 1.00 42.18  ? 234 GLU E CG  1 
ATOM   13035 C  CD  . GLU E 1 234 ? 208.010 257.551 269.817 1.00 55.20  ? 234 GLU E CD  1 
ATOM   13036 O  OE1 . GLU E 1 234 ? 208.871 257.758 270.698 1.00 51.61  ? 234 GLU E OE1 1 
ATOM   13037 O  OE2 . GLU E 1 234 ? 207.211 256.593 269.857 1.00 60.45  ? 234 GLU E OE2 1 
ATOM   13038 N  N   . THR E 1 235 ? 210.139 261.330 268.799 1.00 36.79  ? 235 THR E N   1 
ATOM   13039 C  CA  . THR E 1 235 ? 211.590 261.232 268.745 1.00 34.41  ? 235 THR E CA  1 
ATOM   13040 C  C   . THR E 1 235 ? 212.031 260.095 269.657 1.00 36.72  ? 235 THR E C   1 
ATOM   13041 O  O   . THR E 1 235 ? 211.870 260.175 270.879 1.00 42.19  ? 235 THR E O   1 
ATOM   13042 C  CB  . THR E 1 235 ? 212.250 262.546 269.162 1.00 31.29  ? 235 THR E CB  1 
ATOM   13043 O  OG1 . THR E 1 235 ? 211.688 263.625 268.407 1.00 32.63  ? 235 THR E OG1 1 
ATOM   13044 C  CG2 . THR E 1 235 ? 213.751 262.490 268.917 1.00 31.66  ? 235 THR E CG2 1 
ATOM   13045 N  N   . ILE E 1 236 ? 212.584 259.052 269.060 1.00 33.76  ? 236 ILE E N   1 
ATOM   13046 C  CA  . ILE E 1 236 ? 213.060 257.887 269.792 1.00 34.40  ? 236 ILE E CA  1 
ATOM   13047 C  C   . ILE E 1 236 ? 214.525 258.094 270.143 1.00 36.85  ? 236 ILE E C   1 
ATOM   13048 O  O   . ILE E 1 236 ? 215.349 258.383 269.266 1.00 38.50  ? 236 ILE E O   1 
ATOM   13049 C  CB  . ILE E 1 236 ? 212.865 256.606 268.965 1.00 36.21  ? 236 ILE E CB  1 
ATOM   13050 C  CG1 . ILE E 1 236 ? 211.376 256.315 268.780 1.00 35.51  ? 236 ILE E CG1 1 
ATOM   13051 C  CG2 . ILE E 1 236 ? 213.568 255.433 269.622 1.00 38.94  ? 236 ILE E CG2 1 
ATOM   13052 C  CD1 . ILE E 1 236 ? 211.073 255.408 267.616 1.00 45.94  ? 236 ILE E CD1 1 
ATOM   13053 N  N   . THR E 1 237 ? 214.848 257.956 271.426 1.00 35.91  ? 237 THR E N   1 
ATOM   13054 C  CA  . THR E 1 237 ? 216.218 258.015 271.919 1.00 38.82  ? 237 THR E CA  1 
ATOM   13055 C  C   . THR E 1 237 ? 216.586 256.641 272.460 1.00 39.97  ? 237 THR E C   1 
ATOM   13056 O  O   . THR E 1 237 ? 215.966 256.159 273.414 1.00 45.69  ? 237 THR E O   1 
ATOM   13057 C  CB  . THR E 1 237 ? 216.372 259.080 273.006 1.00 40.54  ? 237 THR E CB  1 
ATOM   13058 O  OG1 . THR E 1 237 ? 215.960 260.352 272.493 1.00 40.22  ? 237 THR E OG1 1 
ATOM   13059 C  CG2 . THR E 1 237 ? 217.821 259.170 273.463 1.00 34.53  ? 237 THR E CG2 1 
ATOM   13060 N  N   . ARG E 1 238 ? 217.590 256.016 271.856 1.00 40.02  ? 238 ARG E N   1 
ATOM   13061 C  CA  . ARG E 1 238 ? 217.955 254.653 272.213 1.00 40.00  ? 238 ARG E CA  1 
ATOM   13062 C  C   . ARG E 1 238 ? 219.442 254.463 271.974 1.00 39.47  ? 238 ARG E C   1 
ATOM   13063 O  O   . ARG E 1 238 ? 220.074 255.274 271.289 1.00 37.89  ? 238 ARG E O   1 
ATOM   13064 C  CB  . ARG E 1 238 ? 217.156 253.625 271.404 1.00 38.08  ? 238 ARG E CB  1 
ATOM   13065 C  CG  . ARG E 1 238 ? 217.378 253.720 269.910 1.00 40.76  ? 238 ARG E CG  1 
ATOM   13066 C  CD  . ARG E 1 238 ? 216.285 253.004 269.148 1.00 39.83  ? 238 ARG E CD  1 
ATOM   13067 N  NE  . ARG E 1 238 ? 216.629 252.821 267.745 1.00 41.61  ? 238 ARG E NE  1 
ATOM   13068 C  CZ  . ARG E 1 238 ? 215.769 252.445 266.809 1.00 46.59  ? 238 ARG E CZ  1 
ATOM   13069 N  NH1 . ARG E 1 238 ? 214.500 252.206 267.094 1.00 55.41  ? 238 ARG E NH1 1 
ATOM   13070 N  NH2 . ARG E 1 238 ? 216.193 252.303 265.557 1.00 41.02  ? 238 ARG E NH2 1 
ATOM   13071 N  N   . PRO E 1 239 ? 220.033 253.407 272.528 1.00 41.19  ? 239 PRO E N   1 
ATOM   13072 C  CA  . PRO E 1 239 ? 221.449 253.137 272.260 1.00 39.11  ? 239 PRO E CA  1 
ATOM   13073 C  C   . PRO E 1 239 ? 221.679 252.808 270.793 1.00 40.59  ? 239 PRO E C   1 
ATOM   13074 O  O   . PRO E 1 239 ? 220.839 252.191 270.134 1.00 39.29  ? 239 PRO E O   1 
ATOM   13075 C  CB  . PRO E 1 239 ? 221.761 251.937 273.164 1.00 36.59  ? 239 PRO E CB  1 
ATOM   13076 C  CG  . PRO E 1 239 ? 220.651 251.900 274.165 1.00 36.53  ? 239 PRO E CG  1 
ATOM   13077 C  CD  . PRO E 1 239 ? 219.450 252.426 273.456 1.00 37.70  ? 239 PRO E CD  1 
ATOM   13078 N  N   . LEU E 1 240 ? 222.835 253.223 270.287 1.00 38.82  ? 240 LEU E N   1 
ATOM   13079 C  CA  . LEU E 1 240 ? 223.177 253.011 268.887 1.00 37.96  ? 240 LEU E CA  1 
ATOM   13080 C  C   . LEU E 1 240 ? 223.470 251.536 268.641 1.00 41.57  ? 240 LEU E C   1 
ATOM   13081 O  O   . LEU E 1 240 ? 224.393 250.973 269.238 1.00 44.04  ? 240 LEU E O   1 
ATOM   13082 C  CB  . LEU E 1 240 ? 224.378 253.873 268.513 1.00 36.74  ? 240 LEU E CB  1 
ATOM   13083 C  CG  . LEU E 1 240 ? 225.150 253.490 267.252 1.00 38.94  ? 240 LEU E CG  1 
ATOM   13084 C  CD1 . LEU E 1 240 ? 224.384 253.929 266.018 1.00 39.04  ? 240 LEU E CD1 1 
ATOM   13085 C  CD2 . LEU E 1 240 ? 226.536 254.105 267.274 1.00 33.01  ? 240 LEU E CD2 1 
ATOM   13086 N  N   . SER E 1 241 ? 222.684 250.906 267.766 1.00 40.44  ? 241 SER E N   1 
ATOM   13087 C  CA  . SER E 1 241 ? 222.849 249.487 267.476 1.00 41.29  ? 241 SER E CA  1 
ATOM   13088 C  C   . SER E 1 241 ? 222.827 249.128 265.998 1.00 39.81  ? 241 SER E C   1 
ATOM   13089 O  O   . SER E 1 241 ? 223.366 248.074 265.640 1.00 37.94  ? 241 SER E O   1 
ATOM   13090 C  CB  . SER E 1 241 ? 221.765 248.664 268.190 1.00 38.90  ? 241 SER E CB  1 
ATOM   13091 O  OG  . SER E 1 241 ? 220.485 248.929 267.646 1.00 44.47  ? 241 SER E OG  1 
ATOM   13092 N  N   . SER E 1 242 ? 222.237 249.947 265.130 1.00 40.51  ? 242 SER E N   1 
ATOM   13093 C  CA  . SER E 1 242 ? 222.078 249.574 263.731 1.00 40.00  ? 242 SER E CA  1 
ATOM   13094 C  C   . SER E 1 242 ? 221.994 250.831 262.876 1.00 37.96  ? 242 SER E C   1 
ATOM   13095 O  O   . SER E 1 242 ? 222.009 251.957 263.380 1.00 38.91  ? 242 SER E O   1 
ATOM   13096 C  CB  . SER E 1 242 ? 220.842 248.691 263.536 1.00 39.70  ? 242 SER E CB  1 
ATOM   13097 O  OG  . SER E 1 242 ? 219.659 249.374 263.912 1.00 38.83  ? 242 SER E OG  1 
ATOM   13098 N  N   . GLU E 1 243 ? 221.907 250.621 261.560 1.00 36.76  ? 243 GLU E N   1 
ATOM   13099 C  CA  . GLU E 1 243 ? 221.787 251.723 260.614 1.00 36.61  ? 243 GLU E CA  1 
ATOM   13100 C  C   . GLU E 1 243 ? 220.428 252.403 260.694 1.00 37.52  ? 243 GLU E C   1 
ATOM   13101 O  O   . GLU E 1 243 ? 220.322 253.590 260.366 1.00 39.49  ? 243 GLU E O   1 
ATOM   13102 C  CB  . GLU E 1 243 ? 222.029 251.221 259.191 1.00 35.59  ? 243 GLU E CB  1 
ATOM   13103 C  CG  . GLU E 1 243 ? 223.411 250.629 258.966 1.00 38.03  ? 243 GLU E CG  1 
ATOM   13104 C  CD  . GLU E 1 243 ? 223.472 249.149 259.298 1.00 48.30  ? 243 GLU E CD  1 
ATOM   13105 O  OE1 . GLU E 1 243 ? 222.534 248.641 259.945 1.00 52.98  ? 243 GLU E OE1 1 
ATOM   13106 O  OE2 . GLU E 1 243 ? 224.460 248.491 258.915 1.00 48.96  ? 243 GLU E OE2 1 
ATOM   13107 N  N   . TYR E 1 244 ? 219.395 251.686 261.139 1.00 39.82  ? 244 TYR E N   1 
ATOM   13108 C  CA  . TYR E 1 244 ? 218.073 252.283 261.264 1.00 37.44  ? 244 TYR E CA  1 
ATOM   13109 C  C   . TYR E 1 244 ? 218.049 253.414 262.278 1.00 37.05  ? 244 TYR E C   1 
ATOM   13110 O  O   . TYR E 1 244 ? 217.091 254.194 262.292 1.00 41.90  ? 244 TYR E O   1 
ATOM   13111 C  CB  . TYR E 1 244 ? 217.047 251.216 261.649 1.00 42.41  ? 244 TYR E CB  1 
ATOM   13112 C  CG  . TYR E 1 244 ? 216.697 250.266 260.524 1.00 50.63  ? 244 TYR E CG  1 
ATOM   13113 C  CD1 . TYR E 1 244 ? 215.851 250.658 259.495 1.00 48.70  ? 244 TYR E CD1 1 
ATOM   13114 C  CD2 . TYR E 1 244 ? 217.210 248.978 260.493 1.00 51.99  ? 244 TYR E CD2 1 
ATOM   13115 C  CE1 . TYR E 1 244 ? 215.530 249.793 258.466 1.00 50.48  ? 244 TYR E CE1 1 
ATOM   13116 C  CE2 . TYR E 1 244 ? 216.894 248.107 259.469 1.00 57.20  ? 244 TYR E CE2 1 
ATOM   13117 C  CZ  . TYR E 1 244 ? 216.054 248.520 258.458 1.00 55.90  ? 244 TYR E CZ  1 
ATOM   13118 O  OH  . TYR E 1 244 ? 215.738 247.654 257.438 1.00 52.22  ? 244 TYR E OH  1 
ATOM   13119 N  N   . ASP E 1 245 ? 219.076 253.522 263.120 1.00 36.07  ? 245 ASP E N   1 
ATOM   13120 C  CA  . ASP E 1 245 ? 219.196 254.651 264.030 1.00 37.03  ? 245 ASP E CA  1 
ATOM   13121 C  C   . ASP E 1 245 ? 219.399 255.970 263.299 1.00 32.06  ? 245 ASP E C   1 
ATOM   13122 O  O   . ASP E 1 245 ? 219.229 257.029 263.912 1.00 36.80  ? 245 ASP E O   1 
ATOM   13123 C  CB  . ASP E 1 245 ? 220.358 254.417 264.997 1.00 36.74  ? 245 ASP E CB  1 
ATOM   13124 C  CG  . ASP E 1 245 ? 220.136 253.218 265.897 1.00 45.45  ? 245 ASP E CG  1 
ATOM   13125 O  OD1 . ASP E 1 245 ? 219.147 252.486 265.687 1.00 45.94  ? 245 ASP E OD1 1 
ATOM   13126 O  OD2 . ASP E 1 245 ? 220.954 253.002 266.814 1.00 48.44  ? 245 ASP E OD2 1 
ATOM   13127 N  N   . PHE E 1 246 ? 219.755 255.936 262.015 1.00 30.24  ? 246 PHE E N   1 
ATOM   13128 C  CA  . PHE E 1 246 ? 220.010 257.146 261.245 1.00 29.43  ? 246 PHE E CA  1 
ATOM   13129 C  C   . PHE E 1 246 ? 218.922 257.433 260.219 1.00 33.10  ? 246 PHE E C   1 
ATOM   13130 O  O   . PHE E 1 246 ? 219.118 258.283 259.345 1.00 32.38  ? 246 PHE E O   1 
ATOM   13131 C  CB  . PHE E 1 246 ? 221.375 257.055 260.561 1.00 24.83  ? 246 PHE E CB  1 
ATOM   13132 C  CG  . PHE E 1 246 ? 222.497 256.730 261.503 1.00 27.71  ? 246 PHE E CG  1 
ATOM   13133 C  CD1 . PHE E 1 246 ? 222.876 257.633 262.480 1.00 25.59  ? 246 PHE E CD1 1 
ATOM   13134 C  CD2 . PHE E 1 246 ? 223.170 255.524 261.416 1.00 27.87  ? 246 PHE E CD2 1 
ATOM   13135 C  CE1 . PHE E 1 246 ? 223.902 257.342 263.351 1.00 26.49  ? 246 PHE E CE1 1 
ATOM   13136 C  CE2 . PHE E 1 246 ? 224.199 255.228 262.285 1.00 28.92  ? 246 PHE E CE2 1 
ATOM   13137 C  CZ  . PHE E 1 246 ? 224.565 256.139 263.254 1.00 28.67  ? 246 PHE E CZ  1 
ATOM   13138 N  N   . LEU E 1 247 ? 217.784 256.753 260.304 1.00 33.89  ? 247 LEU E N   1 
ATOM   13139 C  CA  . LEU E 1 247 ? 216.662 256.981 259.403 1.00 30.12  ? 247 LEU E CA  1 
ATOM   13140 C  C   . LEU E 1 247 ? 215.578 257.763 260.130 1.00 29.92  ? 247 LEU E C   1 
ATOM   13141 O  O   . LEU E 1 247 ? 215.140 257.364 261.214 1.00 35.66  ? 247 LEU E O   1 
ATOM   13142 C  CB  . LEU E 1 247 ? 216.102 255.656 258.884 1.00 33.01  ? 247 LEU E CB  1 
ATOM   13143 C  CG  . LEU E 1 247 ? 214.879 255.751 257.970 1.00 32.65  ? 247 LEU E CG  1 
ATOM   13144 C  CD1 . LEU E 1 247 ? 215.275 256.248 256.589 1.00 26.13  ? 247 LEU E CD1 1 
ATOM   13145 C  CD2 . LEU E 1 247 ? 214.171 254.411 257.881 1.00 32.81  ? 247 LEU E CD2 1 
ATOM   13146 N  N   . ASN E 1 248 ? 215.150 258.872 259.536 1.00 30.39  ? 248 ASN E N   1 
ATOM   13147 C  CA  . ASN E 1 248 ? 214.101 259.715 260.090 1.00 26.83  ? 248 ASN E CA  1 
ATOM   13148 C  C   . ASN E 1 248 ? 212.873 259.626 259.196 1.00 27.27  ? 248 ASN E C   1 
ATOM   13149 O  O   . ASN E 1 248 ? 212.984 259.738 257.972 1.00 28.46  ? 248 ASN E O   1 
ATOM   13150 C  CB  . ASN E 1 248 ? 214.568 261.167 260.206 1.00 25.93  ? 248 ASN E CB  1 
ATOM   13151 C  CG  . ASN E 1 248 ? 215.711 261.336 261.184 1.00 28.76  ? 248 ASN E CG  1 
ATOM   13152 O  OD1 . ASN E 1 248 ? 215.506 261.363 262.395 1.00 33.48  ? 248 ASN E OD1 1 
ATOM   13153 N  ND2 . ASN E 1 248 ? 216.925 261.458 260.661 1.00 29.23  ? 248 ASN E ND2 1 
ATOM   13154 N  N   . THR E 1 249 ? 211.710 259.427 259.807 1.00 25.44  ? 249 THR E N   1 
ATOM   13155 C  CA  . THR E 1 249 ? 210.452 259.299 259.087 1.00 25.19  ? 249 THR E CA  1 
ATOM   13156 C  C   . THR E 1 249 ? 209.519 260.431 259.488 1.00 22.53  ? 249 THR E C   1 
ATOM   13157 O  O   . THR E 1 249 ? 209.379 260.739 260.675 1.00 25.41  ? 249 THR E O   1 
ATOM   13158 C  CB  . THR E 1 249 ? 209.786 257.947 259.369 1.00 31.81  ? 249 THR E CB  1 
ATOM   13159 O  OG1 . THR E 1 249 ? 210.749 256.899 259.213 1.00 38.96  ? 249 THR E OG1 1 
ATOM   13160 C  CG2 . THR E 1 249 ? 208.631 257.712 258.412 1.00 28.55  ? 249 THR E CG2 1 
ATOM   13161 N  N   . TYR E 1 250 ? 208.885 261.053 258.497 1.00 26.35  ? 250 TYR E N   1 
ATOM   13162 C  CA  . TYR E 1 250 ? 207.967 262.155 258.737 1.00 20.50  ? 250 TYR E CA  1 
ATOM   13163 C  C   . TYR E 1 250 ? 206.679 261.943 257.960 1.00 18.62  ? 250 TYR E C   1 
ATOM   13164 O  O   . TYR E 1 250 ? 206.697 261.466 256.820 1.00 22.56  ? 250 TYR E O   1 
ATOM   13165 C  CB  . TYR E 1 250 ? 208.582 263.503 258.341 1.00 19.80  ? 250 TYR E CB  1 
ATOM   13166 C  CG  . TYR E 1 250 ? 209.948 263.769 258.925 1.00 20.69  ? 250 TYR E CG  1 
ATOM   13167 C  CD1 . TYR E 1 250 ? 211.099 263.373 258.261 1.00 21.16  ? 250 TYR E CD1 1 
ATOM   13168 C  CD2 . TYR E 1 250 ? 210.087 264.437 260.133 1.00 22.00  ? 250 TYR E CD2 1 
ATOM   13169 C  CE1 . TYR E 1 250 ? 212.346 263.618 258.790 1.00 22.81  ? 250 TYR E CE1 1 
ATOM   13170 C  CE2 . TYR E 1 250 ? 211.332 264.688 260.669 1.00 23.20  ? 250 TYR E CE2 1 
ATOM   13171 C  CZ  . TYR E 1 250 ? 212.458 264.278 259.993 1.00 26.29  ? 250 TYR E CZ  1 
ATOM   13172 O  OH  . TYR E 1 250 ? 213.701 264.528 260.524 1.00 30.19  ? 250 TYR E OH  1 
ATOM   13173 N  N   . ILE E 1 251 ? 205.564 262.290 258.595 1.00 22.93  ? 251 ILE E N   1 
ATOM   13174 C  CA  . ILE E 1 251 ? 204.270 262.435 257.938 1.00 22.33  ? 251 ILE E CA  1 
ATOM   13175 C  C   . ILE E 1 251 ? 203.816 263.859 258.220 1.00 20.45  ? 251 ILE E C   1 
ATOM   13176 O  O   . ILE E 1 251 ? 203.532 264.211 259.372 1.00 23.53  ? 251 ILE E O   1 
ATOM   13177 C  CB  . ILE E 1 251 ? 203.242 261.412 258.436 1.00 24.69  ? 251 ILE E CB  1 
ATOM   13178 C  CG1 . ILE E 1 251 ? 203.832 260.002 258.397 1.00 25.71  ? 251 ILE E CG1 1 
ATOM   13179 C  CG2 . ILE E 1 251 ? 201.977 261.477 257.593 1.00 25.01  ? 251 ILE E CG2 1 
ATOM   13180 C  CD1 . ILE E 1 251 ? 202.915 258.942 258.957 1.00 32.65  ? 251 ILE E CD1 1 
ATOM   13181 N  N   . VAL E 1 252 ? 203.748 264.678 257.176 1.00 19.78  ? 252 VAL E N   1 
ATOM   13182 C  CA  . VAL E 1 252 ? 203.569 266.118 257.303 1.00 19.81  ? 252 VAL E CA  1 
ATOM   13183 C  C   . VAL E 1 252 ? 202.331 266.519 256.513 1.00 21.26  ? 252 VAL E C   1 
ATOM   13184 O  O   . VAL E 1 252 ? 202.233 266.188 255.331 1.00 24.90  ? 252 VAL E O   1 
ATOM   13185 C  CB  . VAL E 1 252 ? 204.792 266.907 256.802 1.00 18.35  ? 252 VAL E CB  1 
ATOM   13186 C  CG1 . VAL E 1 252 ? 204.816 268.300 257.410 1.00 16.36  ? 252 VAL E CG1 1 
ATOM   13187 C  CG2 . VAL E 1 252 ? 206.073 266.155 257.118 1.00 16.99  ? 252 VAL E CG2 1 
ATOM   13188 N  N   . PRO E 1 253 ? 201.368 267.217 257.116 1.00 24.22  ? 253 PRO E N   1 
ATOM   13189 C  CA  . PRO E 1 253 ? 200.288 267.826 256.325 1.00 20.55  ? 253 PRO E CA  1 
ATOM   13190 C  C   . PRO E 1 253 ? 200.851 268.968 255.491 1.00 19.35  ? 253 PRO E C   1 
ATOM   13191 O  O   . PRO E 1 253 ? 201.430 269.913 256.029 1.00 20.12  ? 253 PRO E O   1 
ATOM   13192 C  CB  . PRO E 1 253 ? 199.301 268.326 257.388 1.00 18.01  ? 253 PRO E CB  1 
ATOM   13193 C  CG  . PRO E 1 253 ? 199.712 267.653 258.665 1.00 17.23  ? 253 PRO E CG  1 
ATOM   13194 C  CD  . PRO E 1 253 ? 201.180 267.422 258.559 1.00 21.38  ? 253 PRO E CD  1 
ATOM   13195 N  N   . ILE E 1 254 ? 200.683 268.876 254.173 1.00 20.70  ? 254 ILE E N   1 
ATOM   13196 C  CA  . ILE E 1 254 ? 201.404 269.736 253.241 1.00 19.15  ? 254 ILE E CA  1 
ATOM   13197 C  C   . ILE E 1 254 ? 200.508 270.736 252.532 1.00 19.56  ? 254 ILE E C   1 
ATOM   13198 O  O   . ILE E 1 254 ? 200.995 271.465 251.658 1.00 20.98  ? 254 ILE E O   1 
ATOM   13199 C  CB  . ILE E 1 254 ? 202.195 268.902 252.214 1.00 17.66  ? 254 ILE E CB  1 
ATOM   13200 C  CG1 . ILE E 1 254 ? 201.284 267.883 251.523 1.00 16.75  ? 254 ILE E CG1 1 
ATOM   13201 C  CG2 . ILE E 1 254 ? 203.385 268.228 252.879 1.00 20.74  ? 254 ILE E CG2 1 
ATOM   13202 C  CD1 . ILE E 1 254 ? 200.675 268.376 250.230 1.00 17.41  ? 254 ILE E CD1 1 
ATOM   13203 N  N   . TYR E 1 255 ? 199.232 270.813 252.875 1.00 21.06  ? 255 TYR E N   1 
ATOM   13204 C  CA  . TYR E 1 255 ? 198.368 271.799 252.235 1.00 21.37  ? 255 TYR E CA  1 
ATOM   13205 C  C   . TYR E 1 255 ? 198.702 273.196 252.751 1.00 22.76  ? 255 TYR E C   1 
ATOM   13206 O  O   . TYR E 1 255 ? 198.864 273.380 253.962 1.00 26.70  ? 255 TYR E O   1 
ATOM   13207 C  CB  . TYR E 1 255 ? 196.899 271.482 252.483 1.00 24.57  ? 255 TYR E CB  1 
ATOM   13208 C  CG  . TYR E 1 255 ? 195.982 272.174 251.507 1.00 24.73  ? 255 TYR E CG  1 
ATOM   13209 C  CD1 . TYR E 1 255 ? 195.722 271.621 250.262 1.00 23.84  ? 255 TYR E CD1 1 
ATOM   13210 C  CD2 . TYR E 1 255 ? 195.392 273.389 251.820 1.00 26.38  ? 255 TYR E CD2 1 
ATOM   13211 C  CE1 . TYR E 1 255 ? 194.892 272.252 249.362 1.00 28.01  ? 255 TYR E CE1 1 
ATOM   13212 C  CE2 . TYR E 1 255 ? 194.560 274.027 250.927 1.00 26.31  ? 255 TYR E CE2 1 
ATOM   13213 C  CZ  . TYR E 1 255 ? 194.314 273.455 249.700 1.00 32.11  ? 255 TYR E CZ  1 
ATOM   13214 O  OH  . TYR E 1 255 ? 193.485 274.088 248.806 1.00 42.08  ? 255 TYR E OH  1 
ATOM   13215 N  N   . PRO E 1 256 ? 198.814 274.197 251.877 1.00 23.00  ? 256 PRO E N   1 
ATOM   13216 C  CA  . PRO E 1 256 ? 199.215 275.531 252.338 1.00 22.30  ? 256 PRO E CA  1 
ATOM   13217 C  C   . PRO E 1 256 ? 198.245 276.093 253.365 1.00 24.42  ? 256 PRO E C   1 
ATOM   13218 O  O   . PRO E 1 256 ? 197.037 275.855 253.311 1.00 30.04  ? 256 PRO E O   1 
ATOM   13219 C  CB  . PRO E 1 256 ? 199.210 276.370 251.054 1.00 20.89  ? 256 PRO E CB  1 
ATOM   13220 C  CG  . PRO E 1 256 ? 199.341 275.388 249.949 1.00 18.97  ? 256 PRO E CG  1 
ATOM   13221 C  CD  . PRO E 1 256 ? 198.671 274.131 250.414 1.00 21.80  ? 256 PRO E CD  1 
ATOM   13222 N  N   . ASP E 1 257 ? 198.793 276.853 254.312 1.00 24.85  ? 257 ASP E N   1 
ATOM   13223 C  CA  . ASP E 1 257 ? 198.000 277.518 255.346 1.00 28.52  ? 257 ASP E CA  1 
ATOM   13224 C  C   . ASP E 1 257 ? 197.528 278.853 254.785 1.00 24.56  ? 257 ASP E C   1 
ATOM   13225 O  O   . ASP E 1 257 ? 198.172 279.887 254.956 1.00 31.15  ? 257 ASP E O   1 
ATOM   13226 C  CB  . ASP E 1 257 ? 198.817 277.695 256.619 1.00 27.85  ? 257 ASP E CB  1 
ATOM   13227 C  CG  . ASP E 1 257 ? 198.103 278.533 257.657 1.00 34.00  ? 257 ASP E CG  1 
ATOM   13228 O  OD1 . ASP E 1 257 ? 196.874 278.377 257.805 1.00 32.86  ? 257 ASP E OD1 1 
ATOM   13229 O  OD2 . ASP E 1 257 ? 198.771 279.350 258.323 1.00 33.48  ? 257 ASP E OD2 1 
ATOM   13230 N  N   . GLU E 1 258 ? 196.381 278.827 254.104 1.00 27.95  ? 258 GLU E N   1 
ATOM   13231 C  CA  . GLU E 1 258 ? 195.880 280.021 253.436 1.00 26.96  ? 258 GLU E CA  1 
ATOM   13232 C  C   . GLU E 1 258 ? 195.363 281.069 254.411 1.00 27.73  ? 258 GLU E C   1 
ATOM   13233 O  O   . GLU E 1 258 ? 195.166 282.221 254.012 1.00 25.75  ? 258 GLU E O   1 
ATOM   13234 C  CB  . GLU E 1 258 ? 194.779 279.643 252.447 1.00 23.73  ? 258 GLU E CB  1 
ATOM   13235 C  CG  . GLU E 1 258 ? 195.112 278.436 251.593 1.00 28.85  ? 258 GLU E CG  1 
ATOM   13236 C  CD  . GLU E 1 258 ? 193.948 277.995 250.732 1.00 39.80  ? 258 GLU E CD  1 
ATOM   13237 O  OE1 . GLU E 1 258 ? 193.051 277.299 251.253 1.00 34.39  ? 258 GLU E OE1 1 
ATOM   13238 O  OE2 . GLU E 1 258 ? 193.930 278.346 249.534 1.00 40.67  ? 258 GLU E OE2 1 
ATOM   13239 N  N   . THR E 1 259 ? 195.139 280.703 255.672 1.00 29.26  ? 259 THR E N   1 
ATOM   13240 C  CA  . THR E 1 259 ? 194.625 281.648 256.654 1.00 24.12  ? 259 THR E CA  1 
ATOM   13241 C  C   . THR E 1 259 ? 195.670 282.654 257.119 1.00 25.32  ? 259 THR E C   1 
ATOM   13242 O  O   . THR E 1 259 ? 195.315 283.602 257.826 1.00 29.38  ? 259 THR E O   1 
ATOM   13243 C  CB  . THR E 1 259 ? 194.062 280.900 257.865 1.00 24.19  ? 259 THR E CB  1 
ATOM   13244 O  OG1 . THR E 1 259 ? 195.103 280.140 258.488 1.00 29.52  ? 259 THR E OG1 1 
ATOM   13245 C  CG2 . THR E 1 259 ? 192.949 279.962 257.437 1.00 18.13  ? 259 THR E CG2 1 
ATOM   13246 N  N   . CYS E 1 260 ? 196.938 282.476 256.740 1.00 24.74  ? 260 CYS E N   1 
ATOM   13247 C  CA  . CYS E 1 260 ? 197.976 283.417 257.149 1.00 21.43  ? 260 CYS E CA  1 
ATOM   13248 C  C   . CYS E 1 260 ? 197.586 284.851 256.815 1.00 22.78  ? 260 CYS E C   1 
ATOM   13249 O  O   . CYS E 1 260 ? 197.759 285.758 257.636 1.00 27.82  ? 260 CYS E O   1 
ATOM   13250 C  CB  . CYS E 1 260 ? 199.307 283.053 256.487 1.00 19.74  ? 260 CYS E CB  1 
ATOM   13251 S  SG  . CYS E 1 260 ? 199.285 283.049 254.679 1.00 26.63  ? 260 CYS E SG  1 
ATOM   13252 N  N   . TRP E 1 261 ? 197.027 285.068 255.621 1.00 21.26  ? 261 TRP E N   1 
ATOM   13253 C  CA  . TRP E 1 261 ? 196.619 286.410 255.220 1.00 19.56  ? 261 TRP E CA  1 
ATOM   13254 C  C   . TRP E 1 261 ? 195.744 287.065 256.280 1.00 24.79  ? 261 TRP E C   1 
ATOM   13255 O  O   . TRP E 1 261 ? 195.892 288.258 256.571 1.00 26.73  ? 261 TRP E O   1 
ATOM   13256 C  CB  . TRP E 1 261 ? 195.876 286.350 253.885 1.00 17.87  ? 261 TRP E CB  1 
ATOM   13257 C  CG  . TRP E 1 261 ? 196.711 285.859 252.744 1.00 18.45  ? 261 TRP E CG  1 
ATOM   13258 C  CD1 . TRP E 1 261 ? 196.699 284.608 252.204 1.00 17.89  ? 261 TRP E CD1 1 
ATOM   13259 C  CD2 . TRP E 1 261 ? 197.668 286.612 251.991 1.00 15.25  ? 261 TRP E CD2 1 
ATOM   13260 N  NE1 . TRP E 1 261 ? 197.596 284.531 251.168 1.00 15.03  ? 261 TRP E NE1 1 
ATOM   13261 C  CE2 . TRP E 1 261 ? 198.203 285.749 251.016 1.00 14.03  ? 261 TRP E CE2 1 
ATOM   13262 C  CE3 . TRP E 1 261 ? 198.127 287.930 252.050 1.00 14.20  ? 261 TRP E CE3 1 
ATOM   13263 C  CZ2 . TRP E 1 261 ? 199.173 286.161 250.107 1.00 12.95  ? 261 TRP E CZ2 1 
ATOM   13264 C  CZ3 . TRP E 1 261 ? 199.088 288.336 251.146 1.00 10.92  ? 261 TRP E CZ3 1 
ATOM   13265 C  CH2 . TRP E 1 261 ? 199.601 287.456 250.188 1.00 12.65  ? 261 TRP E CH2 1 
ATOM   13266 N  N   . VAL E 1 262 ? 194.819 286.302 256.863 1.00 25.92  ? 262 VAL E N   1 
ATOM   13267 C  CA  . VAL E 1 262 ? 193.952 286.852 257.899 1.00 23.87  ? 262 VAL E CA  1 
ATOM   13268 C  C   . VAL E 1 262 ? 194.718 287.037 259.203 1.00 23.55  ? 262 VAL E C   1 
ATOM   13269 O  O   . VAL E 1 262 ? 194.553 288.047 259.897 1.00 25.66  ? 262 VAL E O   1 
ATOM   13270 C  CB  . VAL E 1 262 ? 192.717 285.954 258.090 1.00 24.12  ? 262 VAL E CB  1 
ATOM   13271 C  CG1 . VAL E 1 262 ? 192.066 286.223 259.434 1.00 15.95  ? 262 VAL E CG1 1 
ATOM   13272 C  CG2 . VAL E 1 262 ? 191.728 286.167 256.959 1.00 22.89  ? 262 VAL E CG2 1 
ATOM   13273 N  N   . ASN E 1 263 ? 195.565 286.070 259.559 1.00 25.20  ? 263 ASN E N   1 
ATOM   13274 C  CA  . ASN E 1 263 ? 196.191 286.087 260.876 1.00 25.25  ? 263 ASN E CA  1 
ATOM   13275 C  C   . ASN E 1 263 ? 197.371 287.045 260.951 1.00 25.69  ? 263 ASN E C   1 
ATOM   13276 O  O   . ASN E 1 263 ? 197.631 287.616 262.015 1.00 29.94  ? 263 ASN E O   1 
ATOM   13277 C  CB  . ASN E 1 263 ? 196.636 284.678 261.265 1.00 22.93  ? 263 ASN E CB  1 
ATOM   13278 C  CG  . ASN E 1 263 ? 195.471 283.776 261.610 1.00 26.22  ? 263 ASN E CG  1 
ATOM   13279 O  OD1 . ASN E 1 263 ? 194.573 284.161 262.358 1.00 29.24  ? 263 ASN E OD1 1 
ATOM   13280 N  ND2 . ASN E 1 263 ? 195.481 282.564 261.072 1.00 26.27  ? 263 ASN E ND2 1 
ATOM   13281 N  N   . ASP E 1 264 ? 198.096 287.228 259.848 1.00 24.96  ? 264 ASP E N   1 
ATOM   13282 C  CA  . ASP E 1 264 ? 199.251 288.118 259.872 1.00 23.18  ? 264 ASP E CA  1 
ATOM   13283 C  C   . ASP E 1 264 ? 198.839 289.577 260.002 1.00 25.27  ? 264 ASP E C   1 
ATOM   13284 O  O   . ASP E 1 264 ? 199.584 290.378 260.577 1.00 29.01  ? 264 ASP E O   1 
ATOM   13285 C  CB  . ASP E 1 264 ? 200.097 287.919 258.614 1.00 23.69  ? 264 ASP E CB  1 
ATOM   13286 C  CG  . ASP E 1 264 ? 200.727 286.543 258.545 1.00 28.18  ? 264 ASP E CG  1 
ATOM   13287 O  OD1 . ASP E 1 264 ? 200.768 285.852 259.584 1.00 31.09  ? 264 ASP E OD1 1 
ATOM   13288 O  OD2 . ASP E 1 264 ? 201.179 286.151 257.450 1.00 26.13  ? 264 ASP E OD2 1 
ATOM   13289 N  N   . PHE E 1 265 ? 197.667 289.944 259.482 1.00 23.87  ? 265 PHE E N   1 
ATOM   13290 C  CA  . PHE E 1 265 ? 197.255 291.343 259.379 1.00 22.15  ? 265 PHE E CA  1 
ATOM   13291 C  C   . PHE E 1 265 ? 195.899 291.550 260.038 1.00 24.94  ? 265 PHE E C   1 
ATOM   13292 O  O   . PHE E 1 265 ? 194.853 291.405 259.392 1.00 29.72  ? 265 PHE E O   1 
ATOM   13293 C  CB  . PHE E 1 265 ? 197.224 291.785 257.919 1.00 22.11  ? 265 PHE E CB  1 
ATOM   13294 C  CG  . PHE E 1 265 ? 198.503 291.518 257.192 1.00 26.02  ? 265 PHE E CG  1 
ATOM   13295 C  CD1 . PHE E 1 265 ? 199.618 292.303 257.415 1.00 22.10  ? 265 PHE E CD1 1 
ATOM   13296 C  CD2 . PHE E 1 265 ? 198.597 290.464 256.302 1.00 25.01  ? 265 PHE E CD2 1 
ATOM   13297 C  CE1 . PHE E 1 265 ? 200.798 292.049 256.755 1.00 22.32  ? 265 PHE E CE1 1 
ATOM   13298 C  CE2 . PHE E 1 265 ? 199.773 290.207 255.639 1.00 24.23  ? 265 PHE E CE2 1 
ATOM   13299 C  CZ  . PHE E 1 265 ? 200.876 291.000 255.866 1.00 22.93  ? 265 PHE E CZ  1 
ATOM   13300 N  N   . PRO E 1 266 ? 195.877 291.887 261.324 1.00 27.19  ? 266 PRO E N   1 
ATOM   13301 C  CA  . PRO E 1 266 ? 194.613 292.263 261.964 1.00 26.64  ? 266 PRO E CA  1 
ATOM   13302 C  C   . PRO E 1 266 ? 194.116 293.613 261.470 1.00 24.22  ? 266 PRO E C   1 
ATOM   13303 O  O   . PRO E 1 266 ? 194.893 294.482 261.070 1.00 27.93  ? 266 PRO E O   1 
ATOM   13304 C  CB  . PRO E 1 266 ? 194.966 292.315 263.457 1.00 23.59  ? 266 PRO E CB  1 
ATOM   13305 C  CG  . PRO E 1 266 ? 196.323 291.682 263.577 1.00 24.96  ? 266 PRO E CG  1 
ATOM   13306 C  CD  . PRO E 1 266 ? 197.001 291.905 262.272 1.00 23.99  ? 266 PRO E CD  1 
ATOM   13307 N  N   . ASN E 1 267 ? 192.794 293.781 261.509 1.00 27.65  ? 267 ASN E N   1 
ATOM   13308 C  CA  . ASN E 1 267 ? 192.150 295.034 261.117 1.00 27.13  ? 267 ASN E CA  1 
ATOM   13309 C  C   . ASN E 1 267 ? 192.464 295.393 259.668 1.00 25.22  ? 267 ASN E C   1 
ATOM   13310 O  O   . ASN E 1 267 ? 192.661 296.560 259.326 1.00 29.97  ? 267 ASN E O   1 
ATOM   13311 C  CB  . ASN E 1 267 ? 192.546 296.177 262.053 1.00 22.32  ? 267 ASN E CB  1 
ATOM   13312 C  CG  . ASN E 1 267 ? 192.048 295.972 263.465 1.00 25.38  ? 267 ASN E CG  1 
ATOM   13313 O  OD1 . ASN E 1 267 ? 190.966 295.429 263.680 1.00 31.33  ? 267 ASN E OD1 1 
ATOM   13314 N  ND2 . ASN E 1 267 ? 192.837 296.406 264.439 1.00 27.63  ? 267 ASN E ND2 1 
ATOM   13315 N  N   . ALA E 1 268 ? 192.511 294.379 258.809 1.00 26.23  ? 268 ALA E N   1 
ATOM   13316 C  CA  . ALA E 1 268 ? 192.730 294.571 257.385 1.00 22.15  ? 268 ALA E CA  1 
ATOM   13317 C  C   . ALA E 1 268 ? 191.786 293.666 256.611 1.00 27.15  ? 268 ALA E C   1 
ATOM   13318 O  O   . ALA E 1 268 ? 191.380 292.607 257.096 1.00 33.22  ? 268 ALA E O   1 
ATOM   13319 C  CB  . ALA E 1 268 ? 194.183 294.279 256.990 1.00 19.34  ? 268 ALA E CB  1 
ATOM   13320 N  N   . ARG E 1 269 ? 191.440 294.094 255.397 1.00 27.10  ? 269 ARG E N   1 
ATOM   13321 C  CA  . ARG E 1 269 ? 190.577 293.308 254.515 1.00 27.25  ? 269 ARG E CA  1 
ATOM   13322 C  C   . ARG E 1 269 ? 191.464 292.418 253.651 1.00 31.46  ? 269 ARG E C   1 
ATOM   13323 O  O   . ARG E 1 269 ? 191.697 292.669 252.467 1.00 33.74  ? 269 ARG E O   1 
ATOM   13324 C  CB  . ARG E 1 269 ? 189.692 294.220 253.676 1.00 27.25  ? 269 ARG E CB  1 
ATOM   13325 C  CG  . ARG E 1 269 ? 188.424 294.663 254.380 1.00 31.93  ? 269 ARG E CG  1 
ATOM   13326 C  CD  . ARG E 1 269 ? 187.393 295.174 253.393 1.00 33.82  ? 269 ARG E CD  1 
ATOM   13327 N  NE  . ARG E 1 269 ? 187.279 294.304 252.230 1.00 35.07  ? 269 ARG E NE  1 
ATOM   13328 C  CZ  . ARG E 1 269 ? 186.289 293.444 252.034 1.00 41.05  ? 269 ARG E CZ  1 
ATOM   13329 N  NH1 . ARG E 1 269 ? 185.302 293.316 252.906 1.00 43.06  ? 269 ARG E NH1 1 
ATOM   13330 N  NH2 . ARG E 1 269 ? 186.289 292.693 250.937 1.00 37.33  ? 269 ARG E NH2 1 
ATOM   13331 N  N   . THR E 1 270 ? 191.972 291.352 254.269 1.00 29.99  ? 270 THR E N   1 
ATOM   13332 C  CA  . THR E 1 270 ? 192.897 290.437 253.612 1.00 26.12  ? 270 THR E CA  1 
ATOM   13333 C  C   . THR E 1 270 ? 192.328 289.032 253.461 1.00 27.06  ? 270 THR E C   1 
ATOM   13334 O  O   . THR E 1 270 ? 193.066 288.116 253.080 1.00 32.27  ? 270 THR E O   1 
ATOM   13335 C  CB  . THR E 1 270 ? 194.225 290.382 254.374 1.00 26.06  ? 270 THR E CB  1 
ATOM   13336 O  OG1 . THR E 1 270 ? 193.969 290.207 255.772 1.00 29.81  ? 270 THR E OG1 1 
ATOM   13337 C  CG2 . THR E 1 270 ? 195.006 291.667 254.173 1.00 21.29  ? 270 THR E CG2 1 
ATOM   13338 N  N   . GLU E 1 271 ? 191.041 288.834 253.749 1.00 29.80  ? 271 GLU E N   1 
ATOM   13339 C  CA  . GLU E 1 271 ? 190.433 287.520 253.572 1.00 27.87  ? 271 GLU E CA  1 
ATOM   13340 C  C   . GLU E 1 271 ? 190.243 287.165 252.104 1.00 27.61  ? 271 GLU E C   1 
ATOM   13341 O  O   . GLU E 1 271 ? 190.144 285.978 251.774 1.00 32.61  ? 271 GLU E O   1 
ATOM   13342 C  CB  . GLU E 1 271 ? 189.093 287.455 254.307 1.00 27.71  ? 271 GLU E CB  1 
ATOM   13343 C  CG  . GLU E 1 271 ? 188.116 288.557 253.929 1.00 35.81  ? 271 GLU E CG  1 
ATOM   13344 C  CD  . GLU E 1 271 ? 188.241 289.783 254.817 1.00 42.56  ? 271 GLU E CD  1 
ATOM   13345 O  OE1 . GLU E 1 271 ? 189.260 289.909 255.526 1.00 41.35  ? 271 GLU E OE1 1 
ATOM   13346 O  OE2 . GLU E 1 271 ? 187.317 290.623 254.803 1.00 38.85  ? 271 GLU E OE2 1 
ATOM   13347 N  N   . ILE E 1 272 ? 190.194 288.160 251.217 1.00 26.50  ? 272 ILE E N   1 
ATOM   13348 C  CA  . ILE E 1 272 ? 190.088 287.872 249.790 1.00 28.88  ? 272 ILE E CA  1 
ATOM   13349 C  C   . ILE E 1 272 ? 191.282 287.047 249.328 1.00 25.30  ? 272 ILE E C   1 
ATOM   13350 O  O   . ILE E 1 272 ? 191.142 286.111 248.530 1.00 26.91  ? 272 ILE E O   1 
ATOM   13351 C  CB  . ILE E 1 272 ? 189.952 289.182 248.989 1.00 25.11  ? 272 ILE E CB  1 
ATOM   13352 C  CG1 . ILE E 1 272 ? 189.648 288.886 247.521 1.00 25.65  ? 272 ILE E CG1 1 
ATOM   13353 C  CG2 . ILE E 1 272 ? 191.206 290.031 249.120 1.00 26.13  ? 272 ILE E CG2 1 
ATOM   13354 C  CD1 . ILE E 1 272 ? 188.382 288.098 247.312 1.00 30.31  ? 272 ILE E CD1 1 
ATOM   13355 N  N   . TYR E 1 273 ? 192.473 287.373 249.829 1.00 25.57  ? 273 TYR E N   1 
ATOM   13356 C  CA  . TYR E 1 273 ? 193.660 286.605 249.474 1.00 21.01  ? 273 TYR E CA  1 
ATOM   13357 C  C   . TYR E 1 273 ? 193.646 285.234 250.137 1.00 23.19  ? 273 TYR E C   1 
ATOM   13358 O  O   . TYR E 1 273 ? 194.123 284.253 249.557 1.00 26.84  ? 273 TYR E O   1 
ATOM   13359 C  CB  . TYR E 1 273 ? 194.913 287.387 249.857 1.00 16.43  ? 273 TYR E CB  1 
ATOM   13360 C  CG  . TYR E 1 273 ? 194.908 288.795 249.315 1.00 21.05  ? 273 TYR E CG  1 
ATOM   13361 C  CD1 . TYR E 1 273 ? 194.749 289.035 247.958 1.00 21.11  ? 273 TYR E CD1 1 
ATOM   13362 C  CD2 . TYR E 1 273 ? 195.050 289.886 250.160 1.00 23.26  ? 273 TYR E CD2 1 
ATOM   13363 C  CE1 . TYR E 1 273 ? 194.738 290.318 247.457 1.00 18.64  ? 273 TYR E CE1 1 
ATOM   13364 C  CE2 . TYR E 1 273 ? 195.041 291.174 249.668 1.00 21.97  ? 273 TYR E CE2 1 
ATOM   13365 C  CZ  . TYR E 1 273 ? 194.885 291.384 248.315 1.00 24.01  ? 273 TYR E CZ  1 
ATOM   13366 O  OH  . TYR E 1 273 ? 194.875 292.664 247.815 1.00 27.19  ? 273 TYR E OH  1 
ATOM   13367 N  N   . THR E 1 274 ? 193.107 285.148 251.354 1.00 21.42  ? 274 THR E N   1 
ATOM   13368 C  CA  . THR E 1 274 ? 192.936 283.848 251.990 1.00 21.78  ? 274 THR E CA  1 
ATOM   13369 C  C   . THR E 1 274 ? 191.997 282.958 251.189 1.00 23.31  ? 274 THR E C   1 
ATOM   13370 O  O   . THR E 1 274 ? 192.102 281.728 251.249 1.00 29.47  ? 274 THR E O   1 
ATOM   13371 C  CB  . THR E 1 274 ? 192.415 284.024 253.416 1.00 22.64  ? 274 THR E CB  1 
ATOM   13372 O  OG1 . THR E 1 274 ? 193.502 284.354 254.287 1.00 29.05  ? 274 THR E OG1 1 
ATOM   13373 C  CG2 . THR E 1 274 ? 191.747 282.750 253.906 1.00 19.95  ? 274 THR E CG2 1 
ATOM   13374 N  N   . ARG E 1 275 ? 191.080 283.557 250.433 1.00 24.49  ? 275 ARG E N   1 
ATOM   13375 C  CA  . ARG E 1 275 ? 190.135 282.785 249.639 1.00 23.59  ? 275 ARG E CA  1 
ATOM   13376 C  C   . ARG E 1 275 ? 190.632 282.471 248.236 1.00 24.36  ? 275 ARG E C   1 
ATOM   13377 O  O   . ARG E 1 275 ? 190.280 281.419 247.692 1.00 29.60  ? 275 ARG E O   1 
ATOM   13378 C  CB  . ARG E 1 275 ? 188.801 283.528 249.538 1.00 28.53  ? 275 ARG E CB  1 
ATOM   13379 C  CG  . ARG E 1 275 ? 188.113 283.764 250.867 1.00 30.98  ? 275 ARG E CG  1 
ATOM   13380 C  CD  . ARG E 1 275 ? 186.772 284.436 250.661 1.00 34.19  ? 275 ARG E CD  1 
ATOM   13381 N  NE  . ARG E 1 275 ? 185.887 283.632 249.828 1.00 44.23  ? 275 ARG E NE  1 
ATOM   13382 C  CZ  . ARG E 1 275 ? 184.874 284.118 249.126 1.00 41.51  ? 275 ARG E CZ  1 
ATOM   13383 N  NH1 . ARG E 1 275 ? 184.584 285.409 249.134 1.00 33.84  ? 275 ARG E NH1 1 
ATOM   13384 N  NH2 . ARG E 1 275 ? 184.132 283.289 248.397 1.00 41.02  ? 275 ARG E NH2 1 
ATOM   13385 N  N   . MET E 1 276 ? 191.440 283.344 247.630 1.00 22.69  ? 276 MET E N   1 
ATOM   13386 C  CA  . MET E 1 276 ? 191.710 283.238 246.203 1.00 27.47  ? 276 MET E CA  1 
ATOM   13387 C  C   . MET E 1 276 ? 193.180 283.162 245.812 1.00 23.97  ? 276 MET E C   1 
ATOM   13388 O  O   . MET E 1 276 ? 193.465 282.901 244.638 1.00 25.73  ? 276 MET E O   1 
ATOM   13389 C  CB  . MET E 1 276 ? 191.073 284.422 245.460 1.00 28.26  ? 276 MET E CB  1 
ATOM   13390 C  CG  . MET E 1 276 ? 192.069 285.483 245.029 1.00 34.04  ? 276 MET E CG  1 
ATOM   13391 S  SD  . MET E 1 276 ? 191.297 287.064 244.646 1.00 69.38  ? 276 MET E SD  1 
ATOM   13392 C  CE  . MET E 1 276 ? 190.512 286.694 243.079 1.00 45.64  ? 276 MET E CE  1 
ATOM   13393 N  N   . TYR E 1 277 ? 194.121 283.382 246.731 1.00 19.67  ? 277 TYR E N   1 
ATOM   13394 C  CA  . TYR E 1 277 ? 195.519 283.476 246.316 1.00 22.41  ? 277 TYR E CA  1 
ATOM   13395 C  C   . TYR E 1 277 ? 196.036 282.142 245.788 1.00 22.15  ? 277 TYR E C   1 
ATOM   13396 O  O   . TYR E 1 277 ? 196.617 282.079 244.698 1.00 22.59  ? 277 TYR E O   1 
ATOM   13397 C  CB  . TYR E 1 277 ? 196.389 283.971 247.471 1.00 18.31  ? 277 TYR E CB  1 
ATOM   13398 C  CG  . TYR E 1 277 ? 197.815 284.263 247.064 1.00 14.68  ? 277 TYR E CG  1 
ATOM   13399 C  CD1 . TYR E 1 277 ? 198.124 285.382 246.303 1.00 18.60  ? 277 TYR E CD1 1 
ATOM   13400 C  CD2 . TYR E 1 277 ? 198.852 283.419 247.436 1.00 14.24  ? 277 TYR E CD2 1 
ATOM   13401 C  CE1 . TYR E 1 277 ? 199.425 285.653 245.926 1.00 15.96  ? 277 TYR E CE1 1 
ATOM   13402 C  CE2 . TYR E 1 277 ? 200.155 283.683 247.065 1.00 14.14  ? 277 TYR E CE2 1 
ATOM   13403 C  CZ  . TYR E 1 277 ? 200.436 284.800 246.309 1.00 16.97  ? 277 TYR E CZ  1 
ATOM   13404 O  OH  . TYR E 1 277 ? 201.733 285.064 245.938 1.00 18.72  ? 277 TYR E OH  1 
ATOM   13405 N  N   . PHE E 1 278 ? 195.830 281.063 246.538 1.00 18.94  ? 278 PHE E N   1 
ATOM   13406 C  CA  . PHE E 1 278 ? 196.284 279.741 246.127 1.00 20.53  ? 278 PHE E CA  1 
ATOM   13407 C  C   . PHE E 1 278 ? 195.280 279.019 245.236 1.00 25.73  ? 278 PHE E C   1 
ATOM   13408 O  O   . PHE E 1 278 ? 195.570 277.914 244.768 1.00 30.68  ? 278 PHE E O   1 
ATOM   13409 C  CB  . PHE E 1 278 ? 196.595 278.882 247.360 1.00 20.99  ? 278 PHE E CB  1 
ATOM   13410 C  CG  . PHE E 1 278 ? 197.206 277.545 247.035 1.00 20.83  ? 278 PHE E CG  1 
ATOM   13411 C  CD1 . PHE E 1 278 ? 198.391 277.463 246.326 1.00 19.61  ? 278 PHE E CD1 1 
ATOM   13412 C  CD2 . PHE E 1 278 ? 196.590 276.371 247.437 1.00 23.12  ? 278 PHE E CD2 1 
ATOM   13413 C  CE1 . PHE E 1 278 ? 198.951 276.238 246.024 1.00 17.69  ? 278 PHE E CE1 1 
ATOM   13414 C  CE2 . PHE E 1 278 ? 197.146 275.143 247.139 1.00 23.63  ? 278 PHE E CE2 1 
ATOM   13415 C  CZ  . PHE E 1 278 ? 198.328 275.076 246.432 1.00 20.69  ? 278 PHE E CZ  1 
ATOM   13416 N  N   . ASN E 1 279 ? 194.120 279.618 244.978 1.00 27.93  ? 279 ASN E N   1 
ATOM   13417 C  CA  . ASN E 1 279 ? 193.055 278.961 244.237 1.00 26.57  ? 279 ASN E CA  1 
ATOM   13418 C  C   . ASN E 1 279 ? 192.654 279.684 242.961 1.00 33.04  ? 279 ASN E C   1 
ATOM   13419 O  O   . ASN E 1 279 ? 191.700 279.255 242.302 1.00 39.81  ? 279 ASN E O   1 
ATOM   13420 C  CB  . ASN E 1 279 ? 191.821 278.794 245.132 1.00 26.51  ? 279 ASN E CB  1 
ATOM   13421 C  CG  . ASN E 1 279 ? 192.184 278.469 246.564 1.00 32.17  ? 279 ASN E CG  1 
ATOM   13422 O  OD1 . ASN E 1 279 ? 192.450 277.317 246.902 1.00 37.93  ? 279 ASN E OD1 1 
ATOM   13423 N  ND2 . ASN E 1 279 ? 192.203 279.487 247.414 1.00 30.00  ? 279 ASN E ND2 1 
ATOM   13424 N  N   . HIS E 1 280 ? 193.340 280.761 242.591 1.00 30.29  ? 280 HIS E N   1 
ATOM   13425 C  CA  . HIS E 1 280 ? 192.958 281.480 241.388 1.00 26.52  ? 280 HIS E CA  1 
ATOM   13426 C  C   . HIS E 1 280 ? 193.970 281.247 240.273 1.00 29.66  ? 280 HIS E C   1 
ATOM   13427 O  O   . HIS E 1 280 ? 195.180 281.257 240.521 1.00 30.94  ? 280 HIS E O   1 
ATOM   13428 C  CB  . HIS E 1 280 ? 192.844 282.985 241.661 1.00 28.04  ? 280 HIS E CB  1 
ATOM   13429 C  CG  . HIS E 1 280 ? 192.010 283.719 240.659 1.00 34.11  ? 280 HIS E CG  1 
ATOM   13430 N  ND1 . HIS E 1 280 ? 192.497 284.115 239.432 1.00 33.73  ? 280 HIS E ND1 1 
ATOM   13431 C  CD2 . HIS E 1 280 ? 190.719 284.122 240.699 1.00 37.76  ? 280 HIS E CD2 1 
ATOM   13432 C  CE1 . HIS E 1 280 ? 191.543 284.734 238.761 1.00 29.94  ? 280 HIS E CE1 1 
ATOM   13433 N  NE2 . HIS E 1 280 ? 190.454 284.752 239.507 1.00 38.52  ? 280 HIS E NE2 1 
ATOM   13434 N  N   . PRO E 1 281 ? 193.508 281.025 239.041 1.00 30.80  ? 281 PRO E N   1 
ATOM   13435 C  CA  . PRO E 1 281 ? 194.456 280.828 237.933 1.00 28.22  ? 281 PRO E CA  1 
ATOM   13436 C  C   . PRO E 1 281 ? 195.319 282.043 237.654 1.00 26.85  ? 281 PRO E C   1 
ATOM   13437 O  O   . PRO E 1 281 ? 196.411 281.900 237.091 1.00 26.37  ? 281 PRO E O   1 
ATOM   13438 C  CB  . PRO E 1 281 ? 193.543 280.501 236.743 1.00 23.90  ? 281 PRO E CB  1 
ATOM   13439 C  CG  . PRO E 1 281 ? 192.228 280.125 237.344 1.00 28.72  ? 281 PRO E CG  1 
ATOM   13440 C  CD  . PRO E 1 281 ? 192.110 280.916 238.600 1.00 30.16  ? 281 PRO E CD  1 
ATOM   13441 N  N   . GLY E 1 282 ? 194.859 283.241 238.020 1.00 26.66  ? 282 GLY E N   1 
ATOM   13442 C  CA  . GLY E 1 282 ? 195.659 284.429 237.792 1.00 22.74  ? 282 GLY E CA  1 
ATOM   13443 C  C   . GLY E 1 282 ? 196.864 284.516 238.704 1.00 25.38  ? 282 GLY E C   1 
ATOM   13444 O  O   . GLY E 1 282 ? 197.852 285.174 238.371 1.00 29.61  ? 282 GLY E O   1 
ATOM   13445 N  N   . TYR E 1 283 ? 196.805 283.856 239.855 1.00 24.58  ? 283 TYR E N   1 
ATOM   13446 C  CA  . TYR E 1 283 ? 197.911 283.816 240.799 1.00 22.35  ? 283 TYR E CA  1 
ATOM   13447 C  C   . TYR E 1 283 ? 198.797 282.593 240.607 1.00 20.00  ? 283 TYR E C   1 
ATOM   13448 O  O   . TYR E 1 283 ? 199.601 282.280 241.490 1.00 18.98  ? 283 TYR E O   1 
ATOM   13449 C  CB  . TYR E 1 283 ? 197.377 283.847 242.233 1.00 21.45  ? 283 TYR E CB  1 
ATOM   13450 C  CG  . TYR E 1 283 ? 196.892 285.201 242.691 1.00 20.53  ? 283 TYR E CG  1 
ATOM   13451 C  CD1 . TYR E 1 283 ? 197.668 286.337 242.513 1.00 19.44  ? 283 TYR E CD1 1 
ATOM   13452 C  CD2 . TYR E 1 283 ? 195.656 285.343 243.308 1.00 21.70  ? 283 TYR E CD2 1 
ATOM   13453 C  CE1 . TYR E 1 283 ? 197.230 287.574 242.934 1.00 19.99  ? 283 TYR E CE1 1 
ATOM   13454 C  CE2 . TYR E 1 283 ? 195.209 286.576 243.735 1.00 19.19  ? 283 TYR E CE2 1 
ATOM   13455 C  CZ  . TYR E 1 283 ? 196.000 287.689 243.545 1.00 23.58  ? 283 TYR E CZ  1 
ATOM   13456 O  OH  . TYR E 1 283 ? 195.561 288.922 243.964 1.00 29.32  ? 283 TYR E OH  1 
ATOM   13457 N  N   . ASP E 1 284 ? 198.671 281.900 239.473 1.00 21.48  ? 284 ASP E N   1 
ATOM   13458 C  CA  . ASP E 1 284 ? 199.378 280.637 239.286 1.00 21.09  ? 284 ASP E CA  1 
ATOM   13459 C  C   . ASP E 1 284 ? 200.889 280.827 239.317 1.00 21.46  ? 284 ASP E C   1 
ATOM   13460 O  O   . ASP E 1 284 ? 201.614 280.000 239.881 1.00 22.18  ? 284 ASP E O   1 
ATOM   13461 C  CB  . ASP E 1 284 ? 198.948 279.989 237.970 1.00 20.46  ? 284 ASP E CB  1 
ATOM   13462 C  CG  . ASP E 1 284 ? 197.916 278.901 238.167 1.00 30.67  ? 284 ASP E CG  1 
ATOM   13463 O  OD1 . ASP E 1 284 ? 197.627 278.562 239.331 1.00 28.52  ? 284 ASP E OD1 1 
ATOM   13464 O  OD2 . ASP E 1 284 ? 197.393 278.385 237.159 1.00 43.01  ? 284 ASP E OD2 1 
ATOM   13465 N  N   . ASP E 1 285 ? 201.384 281.905 238.714 1.00 20.85  ? 285 ASP E N   1 
ATOM   13466 C  CA  . ASP E 1 285 ? 202.814 282.153 238.616 1.00 17.11  ? 285 ASP E CA  1 
ATOM   13467 C  C   . ASP E 1 285 ? 203.332 283.041 239.737 1.00 17.68  ? 285 ASP E C   1 
ATOM   13468 O  O   . ASP E 1 285 ? 204.471 283.512 239.666 1.00 24.57  ? 285 ASP E O   1 
ATOM   13469 C  CB  . ASP E 1 285 ? 203.147 282.768 237.257 1.00 20.54  ? 285 ASP E CB  1 
ATOM   13470 C  CG  . ASP E 1 285 ? 203.065 281.760 236.132 1.00 29.80  ? 285 ASP E CG  1 
ATOM   13471 O  OD1 . ASP E 1 285 ? 203.273 280.558 236.398 1.00 34.06  ? 285 ASP E OD1 1 
ATOM   13472 O  OD2 . ASP E 1 285 ? 202.793 282.165 234.984 1.00 38.38  ? 285 ASP E OD2 1 
ATOM   13473 N  N   . TYR E 1 286 ? 202.541 283.280 240.739 1.00 16.16  ? 286 TYR E N   1 
ATOM   13474 C  CA  . TYR E 1 286 ? 202.959 284.007 241.924 1.00 15.17  ? 286 TYR E CA  1 
ATOM   13475 C  C   . TYR E 1 286 ? 203.594 283.053 242.930 1.00 15.98  ? 286 TYR E C   1 
ATOM   13476 O  O   . TYR E 1 286 ? 203.255 281.866 242.969 1.00 16.94  ? 286 TYR E O   1 
ATOM   13477 C  CB  . TYR E 1 286 ? 201.766 284.705 242.569 1.00 16.85  ? 286 TYR E CB  1 
ATOM   13478 C  CG  . TYR E 1 286 ? 201.285 285.936 241.834 1.00 17.18  ? 286 TYR E CG  1 
ATOM   13479 C  CD1 . TYR E 1 286 ? 200.918 285.876 240.497 1.00 18.06  ? 286 TYR E CD1 1 
ATOM   13480 C  CD2 . TYR E 1 286 ? 201.198 287.159 242.480 1.00 18.40  ? 286 TYR E CD2 1 
ATOM   13481 C  CE1 . TYR E 1 286 ? 200.477 286.998 239.827 1.00 18.13  ? 286 TYR E CE1 1 
ATOM   13482 C  CE2 . TYR E 1 286 ? 200.759 288.286 241.819 1.00 19.04  ? 286 TYR E CE2 1 
ATOM   13483 C  CZ  . TYR E 1 286 ? 200.401 288.201 240.493 1.00 22.26  ? 286 TYR E CZ  1 
ATOM   13484 O  OH  . TYR E 1 286 ? 199.963 289.325 239.833 1.00 26.67  ? 286 TYR E OH  1 
ATOM   13485 N  N   . PRO E 1 287 ? 204.519 283.535 243.757 1.00 19.52  ? 287 PRO E N   1 
ATOM   13486 C  CA  . PRO E 1 287 ? 205.152 282.651 244.741 1.00 16.13  ? 287 PRO E CA  1 
ATOM   13487 C  C   . PRO E 1 287 ? 204.143 282.128 245.753 1.00 14.18  ? 287 PRO E C   1 
ATOM   13488 O  O   . PRO E 1 287 ? 203.211 282.827 246.155 1.00 17.62  ? 287 PRO E O   1 
ATOM   13489 C  CB  . PRO E 1 287 ? 206.201 283.550 245.407 1.00 14.73  ? 287 PRO E CB  1 
ATOM   13490 C  CG  . PRO E 1 287 ? 205.743 284.939 245.152 1.00 12.49  ? 287 PRO E CG  1 
ATOM   13491 C  CD  . PRO E 1 287 ? 205.002 284.922 243.853 1.00 15.31  ? 287 PRO E CD  1 
ATOM   13492 N  N   . VAL E 1 288 ? 204.348 280.884 246.170 1.00 14.05  ? 288 VAL E N   1 
ATOM   13493 C  CA  . VAL E 1 288 ? 203.480 280.245 247.152 1.00 12.63  ? 288 VAL E CA  1 
ATOM   13494 C  C   . VAL E 1 288 ? 203.849 280.730 248.548 1.00 14.46  ? 288 VAL E C   1 
ATOM   13495 O  O   . VAL E 1 288 ? 205.031 280.822 248.901 1.00 17.34  ? 288 VAL E O   1 
ATOM   13496 C  CB  . VAL E 1 288 ? 203.580 278.711 247.040 1.00 13.27  ? 288 VAL E CB  1 
ATOM   13497 C  CG1 . VAL E 1 288 ? 204.943 278.226 247.499 1.00 9.30   ? 288 VAL E CG1 1 
ATOM   13498 C  CG2 . VAL E 1 288 ? 202.468 278.033 247.832 1.00 12.90  ? 288 VAL E CG2 1 
ATOM   13499 N  N   . VAL E 1 289 ? 202.833 281.051 249.347 1.00 16.45  ? 289 VAL E N   1 
ATOM   13500 C  CA  . VAL E 1 289 ? 203.034 281.484 250.726 1.00 14.36  ? 289 VAL E CA  1 
ATOM   13501 C  C   . VAL E 1 289 ? 202.264 280.553 251.649 1.00 15.01  ? 289 VAL E C   1 
ATOM   13502 O  O   . VAL E 1 289 ? 201.602 279.616 251.190 1.00 17.73  ? 289 VAL E O   1 
ATOM   13503 C  CB  . VAL E 1 289 ? 202.598 282.946 250.934 1.00 12.55  ? 289 VAL E CB  1 
ATOM   13504 C  CG1 . VAL E 1 289 ? 203.394 283.876 250.034 1.00 11.86  ? 289 VAL E CG1 1 
ATOM   13505 C  CG2 . VAL E 1 289 ? 201.110 283.090 250.685 1.00 11.99  ? 289 VAL E CG2 1 
ATOM   13506 N  N   . GLY E 1 290 ? 202.342 280.803 252.953 1.00 14.81  ? 290 GLY E N   1 
ATOM   13507 C  CA  . GLY E 1 290 ? 201.689 279.936 253.911 1.00 14.01  ? 290 GLY E CA  1 
ATOM   13508 C  C   . GLY E 1 290 ? 202.324 278.575 254.046 1.00 18.20  ? 290 GLY E C   1 
ATOM   13509 O  O   . GLY E 1 290 ? 201.701 277.658 254.584 1.00 24.32  ? 290 GLY E O   1 
ATOM   13510 N  N   . ILE E 1 291 ? 203.554 278.419 253.567 1.00 18.26  ? 291 ILE E N   1 
ATOM   13511 C  CA  . ILE E 1 291 ? 204.274 277.153 253.603 1.00 13.52  ? 291 ILE E CA  1 
ATOM   13512 C  C   . ILE E 1 291 ? 205.270 277.204 254.750 1.00 17.43  ? 291 ILE E C   1 
ATOM   13513 O  O   . ILE E 1 291 ? 206.068 278.144 254.848 1.00 21.54  ? 291 ILE E O   1 
ATOM   13514 C  CB  . ILE E 1 291 ? 204.981 276.882 252.264 1.00 15.37  ? 291 ILE E CB  1 
ATOM   13515 C  CG1 . ILE E 1 291 ? 203.963 276.869 251.120 1.00 13.59  ? 291 ILE E CG1 1 
ATOM   13516 C  CG2 . ILE E 1 291 ? 205.772 275.583 252.317 1.00 13.94  ? 291 ILE E CG2 1 
ATOM   13517 C  CD1 . ILE E 1 291 ? 202.848 275.865 251.299 1.00 16.18  ? 291 ILE E CD1 1 
ATOM   13518 N  N   . SER E 1 292 ? 205.221 276.207 255.622 1.00 17.53  ? 292 SER E N   1 
ATOM   13519 C  CA  . SER E 1 292 ? 206.130 276.156 256.753 1.00 15.10  ? 292 SER E CA  1 
ATOM   13520 C  C   . SER E 1 292 ? 207.431 275.458 256.362 1.00 15.97  ? 292 SER E C   1 
ATOM   13521 O  O   . SER E 1 292 ? 207.565 274.888 255.277 1.00 19.07  ? 292 SER E O   1 
ATOM   13522 C  CB  . SER E 1 292 ? 205.467 275.457 257.941 1.00 14.31  ? 292 SER E CB  1 
ATOM   13523 O  OG  . SER E 1 292 ? 205.788 274.081 257.978 1.00 21.45  ? 292 SER E OG  1 
ATOM   13524 N  N   . TRP E 1 293 ? 208.407 275.520 257.268 1.00 14.12  ? 293 TRP E N   1 
ATOM   13525 C  CA  . TRP E 1 293 ? 209.707 274.909 257.010 1.00 11.35  ? 293 TRP E CA  1 
ATOM   13526 C  C   . TRP E 1 293 ? 209.574 273.405 256.786 1.00 15.48  ? 293 TRP E C   1 
ATOM   13527 O  O   . TRP E 1 293 ? 210.196 272.842 255.876 1.00 18.13  ? 293 TRP E O   1 
ATOM   13528 C  CB  . TRP E 1 293 ? 210.646 275.220 258.179 1.00 11.36  ? 293 TRP E CB  1 
ATOM   13529 C  CG  . TRP E 1 293 ? 212.077 274.849 257.972 1.00 11.34  ? 293 TRP E CG  1 
ATOM   13530 C  CD1 . TRP E 1 293 ? 213.017 275.561 257.291 1.00 11.09  ? 293 TRP E CD1 1 
ATOM   13531 C  CD2 . TRP E 1 293 ? 212.743 273.693 258.485 1.00 12.60  ? 293 TRP E CD2 1 
ATOM   13532 N  NE1 . TRP E 1 293 ? 214.223 274.910 257.330 1.00 13.18  ? 293 TRP E NE1 1 
ATOM   13533 C  CE2 . TRP E 1 293 ? 214.083 273.760 258.060 1.00 13.83  ? 293 TRP E CE2 1 
ATOM   13534 C  CE3 . TRP E 1 293 ? 212.335 272.602 259.257 1.00 13.10  ? 293 TRP E CE3 1 
ATOM   13535 C  CZ2 . TRP E 1 293 ? 215.016 272.779 258.378 1.00 16.20  ? 293 TRP E CZ2 1 
ATOM   13536 C  CZ3 . TRP E 1 293 ? 213.261 271.631 259.571 1.00 13.88  ? 293 TRP E CZ3 1 
ATOM   13537 C  CH2 . TRP E 1 293 ? 214.586 271.726 259.134 1.00 15.36  ? 293 TRP E CH2 1 
ATOM   13538 N  N   . GLU E 1 294 ? 208.751 272.741 257.599 1.00 14.69  ? 294 GLU E N   1 
ATOM   13539 C  CA  . GLU E 1 294 ? 208.537 271.306 257.439 1.00 16.57  ? 294 GLU E CA  1 
ATOM   13540 C  C   . GLU E 1 294 ? 207.869 270.986 256.107 1.00 17.46  ? 294 GLU E C   1 
ATOM   13541 O  O   . GLU E 1 294 ? 208.226 270.007 255.442 1.00 21.38  ? 294 GLU E O   1 
ATOM   13542 C  CB  . GLU E 1 294 ? 207.701 270.778 258.604 1.00 17.01  ? 294 GLU E CB  1 
ATOM   13543 C  CG  . GLU E 1 294 ? 208.242 271.166 259.969 1.00 19.31  ? 294 GLU E CG  1 
ATOM   13544 C  CD  . GLU E 1 294 ? 207.252 270.912 261.086 1.00 31.33  ? 294 GLU E CD  1 
ATOM   13545 O  OE1 . GLU E 1 294 ? 206.057 270.715 260.788 1.00 37.82  ? 294 GLU E OE1 1 
ATOM   13546 O  OE2 . GLU E 1 294 ? 207.667 270.908 262.263 1.00 31.12  ? 294 GLU E OE2 1 
ATOM   13547 N  N   . GLN E 1 295 ? 206.888 271.795 255.703 1.00 16.15  ? 295 GLN E N   1 
ATOM   13548 C  CA  . GLN E 1 295 ? 206.231 271.568 254.421 1.00 18.41  ? 295 GLN E CA  1 
ATOM   13549 C  C   . GLN E 1 295 ? 207.195 271.784 253.262 1.00 18.06  ? 295 GLN E C   1 
ATOM   13550 O  O   . GLN E 1 295 ? 207.135 271.071 252.255 1.00 19.29  ? 295 GLN E O   1 
ATOM   13551 C  CB  . GLN E 1 295 ? 205.010 272.477 254.288 1.00 17.83  ? 295 GLN E CB  1 
ATOM   13552 C  CG  . GLN E 1 295 ? 203.909 272.170 255.284 1.00 16.78  ? 295 GLN E CG  1 
ATOM   13553 C  CD  . GLN E 1 295 ? 202.813 273.210 255.282 1.00 20.02  ? 295 GLN E CD  1 
ATOM   13554 O  OE1 . GLN E 1 295 ? 203.082 274.409 255.290 1.00 24.77  ? 295 GLN E OE1 1 
ATOM   13555 N  NE2 . GLN E 1 295 ? 201.568 272.758 255.285 1.00 21.16  ? 295 GLN E NE2 1 
ATOM   13556 N  N   . ALA E 1 296 ? 208.088 272.770 253.380 1.00 17.79  ? 296 ALA E N   1 
ATOM   13557 C  CA  . ALA E 1 296 ? 209.099 272.979 252.349 1.00 14.60  ? 296 ALA E CA  1 
ATOM   13558 C  C   . ALA E 1 296 ? 210.046 271.790 252.258 1.00 18.38  ? 296 ALA E C   1 
ATOM   13559 O  O   . ALA E 1 296 ? 210.417 271.363 251.157 1.00 24.67  ? 296 ALA E O   1 
ATOM   13560 C  CB  . ALA E 1 296 ? 209.875 274.267 252.627 1.00 13.64  ? 296 ALA E CB  1 
ATOM   13561 N  N   . GLN E 1 297 ? 210.451 271.240 253.405 1.00 16.18  ? 297 GLN E N   1 
ATOM   13562 C  CA  . GLN E 1 297 ? 211.296 270.050 253.384 1.00 17.25  ? 297 GLN E CA  1 
ATOM   13563 C  C   . GLN E 1 297 ? 210.574 268.873 252.740 1.00 18.75  ? 297 GLN E C   1 
ATOM   13564 O  O   . GLN E 1 297 ? 211.168 268.115 251.962 1.00 25.51  ? 297 GLN E O   1 
ATOM   13565 C  CB  . GLN E 1 297 ? 211.740 269.696 254.801 1.00 18.26  ? 297 GLN E CB  1 
ATOM   13566 C  CG  . GLN E 1 297 ? 212.500 270.805 255.497 1.00 21.02  ? 297 GLN E CG  1 
ATOM   13567 C  CD  . GLN E 1 297 ? 213.881 270.374 255.932 1.00 30.61  ? 297 GLN E CD  1 
ATOM   13568 O  OE1 . GLN E 1 297 ? 214.031 269.570 256.850 1.00 40.44  ? 297 GLN E OE1 1 
ATOM   13569 N  NE2 . GLN E 1 297 ? 214.901 270.905 255.271 1.00 29.16  ? 297 GLN E NE2 1 
ATOM   13570 N  N   . ALA E 1 298 ? 209.289 268.700 253.057 1.00 19.30  ? 298 ALA E N   1 
ATOM   13571 C  CA  . ALA E 1 298 ? 208.510 267.634 252.437 1.00 16.14  ? 298 ALA E CA  1 
ATOM   13572 C  C   . ALA E 1 298 ? 208.414 267.826 250.928 1.00 21.56  ? 298 ALA E C   1 
ATOM   13573 O  O   . ALA E 1 298 ? 208.520 266.861 250.162 1.00 24.35  ? 298 ALA E O   1 
ATOM   13574 C  CB  . ALA E 1 298 ? 207.119 267.571 253.064 1.00 13.94  ? 298 ALA E CB  1 
ATOM   13575 N  N   . PHE E 1 299 ? 208.208 269.066 250.482 1.00 19.89  ? 299 PHE E N   1 
ATOM   13576 C  CA  . PHE E 1 299 ? 208.164 269.341 249.051 1.00 16.78  ? 299 PHE E CA  1 
ATOM   13577 C  C   . PHE E 1 299 ? 209.492 269.011 248.387 1.00 20.06  ? 299 PHE E C   1 
ATOM   13578 O  O   . PHE E 1 299 ? 209.521 268.461 247.282 1.00 21.43  ? 299 PHE E O   1 
ATOM   13579 C  CB  . PHE E 1 299 ? 207.791 270.804 248.804 1.00 15.38  ? 299 PHE E CB  1 
ATOM   13580 C  CG  . PHE E 1 299 ? 207.894 271.226 247.362 1.00 15.96  ? 299 PHE E CG  1 
ATOM   13581 C  CD1 . PHE E 1 299 ? 209.090 271.701 246.848 1.00 12.52  ? 299 PHE E CD1 1 
ATOM   13582 C  CD2 . PHE E 1 299 ? 206.797 271.148 246.523 1.00 13.56  ? 299 PHE E CD2 1 
ATOM   13583 C  CE1 . PHE E 1 299 ? 209.187 272.083 245.529 1.00 12.21  ? 299 PHE E CE1 1 
ATOM   13584 C  CE2 . PHE E 1 299 ? 206.890 271.535 245.202 1.00 11.53  ? 299 PHE E CE2 1 
ATOM   13585 C  CZ  . PHE E 1 299 ? 208.087 272.001 244.706 1.00 11.03  ? 299 PHE E CZ  1 
ATOM   13586 N  N   . CYS E 1 300 ? 210.606 269.357 249.035 1.00 20.05  ? 300 CYS E N   1 
ATOM   13587 C  CA  . CYS E 1 300 ? 211.910 269.044 248.460 1.00 18.43  ? 300 CYS E CA  1 
ATOM   13588 C  C   . CYS E 1 300 ? 212.125 267.538 248.367 1.00 19.71  ? 300 CYS E C   1 
ATOM   13589 O  O   . CYS E 1 300 ? 212.662 267.038 247.371 1.00 25.54  ? 300 CYS E O   1 
ATOM   13590 C  CB  . CYS E 1 300 ? 213.020 269.701 249.279 1.00 15.55  ? 300 CYS E CB  1 
ATOM   13591 S  SG  . CYS E 1 300 ? 213.083 271.502 249.139 1.00 28.81  ? 300 CYS E SG  1 
ATOM   13592 N  N   . ALA E 1 301 ? 211.712 266.798 249.398 1.00 22.39  ? 301 ALA E N   1 
ATOM   13593 C  CA  . ALA E 1 301 ? 211.825 265.343 249.351 1.00 18.20  ? 301 ALA E CA  1 
ATOM   13594 C  C   . ALA E 1 301 ? 210.979 264.760 248.226 1.00 19.85  ? 301 ALA E C   1 
ATOM   13595 O  O   . ALA E 1 301 ? 211.422 263.856 247.505 1.00 25.35  ? 301 ALA E O   1 
ATOM   13596 C  CB  . ALA E 1 301 ? 211.419 264.741 250.695 1.00 14.24  ? 301 ALA E CB  1 
ATOM   13597 N  N   . TRP E 1 302 ? 209.754 265.263 248.061 1.00 20.07  ? 302 TRP E N   1 
ATOM   13598 C  CA  . TRP E 1 302 ? 208.902 264.783 246.979 1.00 18.30  ? 302 TRP E CA  1 
ATOM   13599 C  C   . TRP E 1 302 ? 209.508 265.106 245.621 1.00 20.51  ? 302 TRP E C   1 
ATOM   13600 O  O   . TRP E 1 302 ? 209.422 264.303 244.687 1.00 26.12  ? 302 TRP E O   1 
ATOM   13601 C  CB  . TRP E 1 302 ? 207.506 265.389 247.090 1.00 18.38  ? 302 TRP E CB  1 
ATOM   13602 C  CG  . TRP E 1 302 ? 206.741 265.303 245.810 1.00 20.55  ? 302 TRP E CG  1 
ATOM   13603 C  CD1 . TRP E 1 302 ? 206.021 264.238 245.358 1.00 18.30  ? 302 TRP E CD1 1 
ATOM   13604 C  CD2 . TRP E 1 302 ? 206.637 266.315 244.803 1.00 22.15  ? 302 TRP E CD2 1 
ATOM   13605 N  NE1 . TRP E 1 302 ? 205.467 264.527 244.136 1.00 19.23  ? 302 TRP E NE1 1 
ATOM   13606 C  CE2 . TRP E 1 302 ? 205.831 265.796 243.773 1.00 18.37  ? 302 TRP E CE2 1 
ATOM   13607 C  CE3 . TRP E 1 302 ? 207.144 267.611 244.675 1.00 19.48  ? 302 TRP E CE3 1 
ATOM   13608 C  CZ2 . TRP E 1 302 ? 205.520 266.527 242.632 1.00 18.60  ? 302 TRP E CZ2 1 
ATOM   13609 C  CZ3 . TRP E 1 302 ? 206.837 268.333 243.542 1.00 19.17  ? 302 TRP E CZ3 1 
ATOM   13610 C  CH2 . TRP E 1 302 ? 206.031 267.791 242.535 1.00 20.69  ? 302 TRP E CH2 1 
ATOM   13611 N  N   . ARG E 1 303 ? 210.102 266.291 245.486 1.00 24.15  ? 303 ARG E N   1 
ATOM   13612 C  CA  . ARG E 1 303 ? 210.739 266.669 244.231 1.00 23.38  ? 303 ARG E CA  1 
ATOM   13613 C  C   . ARG E 1 303 ? 211.912 265.752 243.913 1.00 24.12  ? 303 ARG E C   1 
ATOM   13614 O  O   . ARG E 1 303 ? 212.095 265.339 242.762 1.00 27.01  ? 303 ARG E O   1 
ATOM   13615 C  CB  . ARG E 1 303 ? 211.191 268.125 244.304 1.00 20.59  ? 303 ARG E CB  1 
ATOM   13616 C  CG  . ARG E 1 303 ? 211.279 268.831 242.973 1.00 19.64  ? 303 ARG E CG  1 
ATOM   13617 C  CD  . ARG E 1 303 ? 212.059 270.116 243.121 1.00 22.06  ? 303 ARG E CD  1 
ATOM   13618 N  NE  . ARG E 1 303 ? 212.374 270.729 241.838 1.00 19.98  ? 303 ARG E NE  1 
ATOM   13619 C  CZ  . ARG E 1 303 ? 212.816 271.970 241.694 1.00 20.26  ? 303 ARG E CZ  1 
ATOM   13620 N  NH1 . ARG E 1 303 ? 212.998 272.763 242.736 1.00 19.40  ? 303 ARG E NH1 1 
ATOM   13621 N  NH2 . ARG E 1 303 ? 213.080 272.427 240.475 1.00 28.43  ? 303 ARG E NH2 1 
ATOM   13622 N  N   . SER E 1 304 ? 212.719 265.423 244.924 1.00 23.89  ? 304 SER E N   1 
ATOM   13623 C  CA  . SER E 1 304 ? 213.820 264.486 244.717 1.00 26.72  ? 304 SER E CA  1 
ATOM   13624 C  C   . SER E 1 304 ? 213.301 263.118 244.292 1.00 33.94  ? 304 SER E C   1 
ATOM   13625 O  O   . SER E 1 304 ? 213.839 262.493 243.368 1.00 39.40  ? 304 SER E O   1 
ATOM   13626 C  CB  . SER E 1 304 ? 214.657 264.371 245.989 1.00 27.53  ? 304 SER E CB  1 
ATOM   13627 O  OG  . SER E 1 304 ? 215.086 265.643 246.433 1.00 28.92  ? 304 SER E OG  1 
ATOM   13628 N  N   . GLU E 1 305 ? 212.256 262.632 244.964 1.00 34.40  ? 305 GLU E N   1 
ATOM   13629 C  CA  . GLU E 1 305 ? 211.688 261.334 244.611 1.00 34.86  ? 305 GLU E CA  1 
ATOM   13630 C  C   . GLU E 1 305 ? 211.165 261.340 243.180 1.00 38.86  ? 305 GLU E C   1 
ATOM   13631 O  O   . GLU E 1 305 ? 211.399 260.400 242.414 1.00 43.23  ? 305 GLU E O   1 
ATOM   13632 C  CB  . GLU E 1 305 ? 210.576 260.969 245.595 1.00 36.53  ? 305 GLU E CB  1 
ATOM   13633 C  CG  . GLU E 1 305 ? 210.496 259.492 245.932 1.00 47.90  ? 305 GLU E CG  1 
ATOM   13634 C  CD  . GLU E 1 305 ? 209.103 259.065 246.355 1.00 59.64  ? 305 GLU E CD  1 
ATOM   13635 O  OE1 . GLU E 1 305 ? 208.134 259.777 246.016 1.00 54.05  ? 305 GLU E OE1 1 
ATOM   13636 O  OE2 . GLU E 1 305 ? 208.975 258.019 247.026 1.00 61.71  ? 305 GLU E OE2 1 
ATOM   13637 N  N   . PHE E 1 306 ? 210.450 262.402 242.806 1.00 34.74  ? 306 PHE E N   1 
ATOM   13638 C  CA  . PHE E 1 306 ? 209.930 262.537 241.450 1.00 34.46  ? 306 PHE E CA  1 
ATOM   13639 C  C   . PHE E 1 306 ? 211.056 262.521 240.425 1.00 40.51  ? 306 PHE E C   1 
ATOM   13640 O  O   . PHE E 1 306 ? 210.995 261.795 239.422 1.00 46.20  ? 306 PHE E O   1 
ATOM   13641 C  CB  . PHE E 1 306 ? 209.133 263.839 241.357 1.00 30.19  ? 306 PHE E CB  1 
ATOM   13642 C  CG  . PHE E 1 306 ? 207.968 263.787 240.419 1.00 32.71  ? 306 PHE E CG  1 
ATOM   13643 C  CD1 . PHE E 1 306 ? 206.877 262.984 240.694 1.00 37.23  ? 306 PHE E CD1 1 
ATOM   13644 C  CD2 . PHE E 1 306 ? 207.948 264.571 239.280 1.00 36.17  ? 306 PHE E CD2 1 
ATOM   13645 C  CE1 . PHE E 1 306 ? 205.798 262.946 239.839 1.00 38.42  ? 306 PHE E CE1 1 
ATOM   13646 C  CE2 . PHE E 1 306 ? 206.873 264.538 238.421 1.00 36.92  ? 306 PHE E CE2 1 
ATOM   13647 C  CZ  . PHE E 1 306 ? 205.795 263.724 238.701 1.00 39.57  ? 306 PHE E CZ  1 
ATOM   13648 N  N   . PHE E 1 307 ? 212.100 263.317 240.666 1.00 41.26  ? 307 PHE E N   1 
ATOM   13649 C  CA  . PHE E 1 307 ? 213.211 263.396 239.726 1.00 40.15  ? 307 PHE E CA  1 
ATOM   13650 C  C   . PHE E 1 307 ? 213.894 262.044 239.570 1.00 51.00  ? 307 PHE E C   1 
ATOM   13651 O  O   . PHE E 1 307 ? 214.195 261.622 238.448 1.00 59.23  ? 307 PHE E O   1 
ATOM   13652 C  CB  . PHE E 1 307 ? 214.201 264.463 240.192 1.00 42.96  ? 307 PHE E CB  1 
ATOM   13653 C  CG  . PHE E 1 307 ? 215.223 264.845 239.160 1.00 48.84  ? 307 PHE E CG  1 
ATOM   13654 C  CD1 . PHE E 1 307 ? 215.146 266.067 238.517 1.00 50.52  ? 307 PHE E CD1 1 
ATOM   13655 C  CD2 . PHE E 1 307 ? 216.272 263.997 238.851 1.00 57.84  ? 307 PHE E CD2 1 
ATOM   13656 C  CE1 . PHE E 1 307 ? 216.084 266.429 237.572 1.00 57.96  ? 307 PHE E CE1 1 
ATOM   13657 C  CE2 . PHE E 1 307 ? 217.213 264.353 237.907 1.00 63.02  ? 307 PHE E CE2 1 
ATOM   13658 C  CZ  . PHE E 1 307 ? 217.119 265.571 237.267 1.00 63.15  ? 307 PHE E CZ  1 
ATOM   13659 N  N   . ARG E 1 308 ? 214.141 261.344 240.681 1.00 53.31  ? 308 ARG E N   1 
ATOM   13660 C  CA  . ARG E 1 308 ? 214.755 260.024 240.582 1.00 52.83  ? 308 ARG E CA  1 
ATOM   13661 C  C   . ARG E 1 308 ? 213.852 259.052 239.834 1.00 55.59  ? 308 ARG E C   1 
ATOM   13662 O  O   . ARG E 1 308 ? 214.331 258.248 239.026 1.00 62.10  ? 308 ARG E O   1 
ATOM   13663 C  CB  . ARG E 1 308 ? 215.090 259.485 241.972 1.00 46.90  ? 308 ARG E CB  1 
ATOM   13664 C  CG  . ARG E 1 308 ? 216.189 260.251 242.685 1.00 48.74  ? 308 ARG E CG  1 
ATOM   13665 C  CD  . ARG E 1 308 ? 216.555 259.585 243.998 1.00 50.01  ? 308 ARG E CD  1 
ATOM   13666 N  NE  . ARG E 1 308 ? 215.393 258.987 244.644 1.00 58.07  ? 308 ARG E NE  1 
ATOM   13667 C  CZ  . ARG E 1 308 ? 214.792 259.485 245.716 1.00 58.76  ? 308 ARG E CZ  1 
ATOM   13668 N  NH1 . ARG E 1 308 ? 215.219 260.595 246.294 1.00 50.89  ? 308 ARG E NH1 1 
ATOM   13669 N  NH2 . ARG E 1 308 ? 213.737 258.853 246.219 1.00 53.46  ? 308 ARG E NH2 1 
ATOM   13670 N  N   . LYS E 1 309 ? 212.544 259.108 240.089 1.00 56.49  ? 309 LYS E N   1 
ATOM   13671 C  CA  . LYS E 1 309 ? 211.608 258.252 239.372 1.00 57.97  ? 309 LYS E CA  1 
ATOM   13672 C  C   . LYS E 1 309 ? 211.611 258.525 237.876 1.00 60.79  ? 309 LYS E C   1 
ATOM   13673 O  O   . LYS E 1 309 ? 211.338 257.611 237.091 1.00 63.18  ? 309 LYS E O   1 
ATOM   13674 C  CB  . LYS E 1 309 ? 210.195 258.440 239.926 1.00 50.72  ? 309 LYS E CB  1 
ATOM   13675 C  CG  . LYS E 1 309 ? 209.728 257.330 240.846 1.00 57.35  ? 309 LYS E CG  1 
ATOM   13676 C  CD  . LYS E 1 309 ? 208.211 257.292 240.922 1.00 63.94  ? 309 LYS E CD  1 
ATOM   13677 C  CE  . LYS E 1 309 ? 207.623 256.377 239.861 1.00 71.05  ? 309 LYS E CE  1 
ATOM   13678 N  NZ  . LYS E 1 309 ? 206.577 255.479 240.424 1.00 65.67  ? 309 LYS E NZ  1 
ATOM   13679 N  N   . GLY E 1 310 ? 211.912 259.753 237.463 1.00 66.23  ? 310 GLY E N   1 
ATOM   13680 C  CA  . GLY E 1 310 ? 211.867 260.074 236.049 1.00 71.02  ? 310 GLY E CA  1 
ATOM   13681 C  C   . GLY E 1 310 ? 213.206 260.131 235.339 1.00 76.07  ? 310 GLY E C   1 
ATOM   13682 O  O   . GLY E 1 310 ? 213.417 261.011 234.499 1.00 78.06  ? 310 GLY E O   1 
ATOM   13683 N  N   . ILE E 1 311 ? 214.117 259.206 235.648 1.00 79.60  ? 311 ILE E N   1 
ATOM   13684 C  CA  . ILE E 1 311 ? 215.441 259.195 235.033 1.00 82.94  ? 311 ILE E CA  1 
ATOM   13685 C  C   . ILE E 1 311 ? 216.021 257.789 235.113 1.00 88.18  ? 311 ILE E C   1 
ATOM   13686 O  O   . ILE E 1 311 ? 215.695 257.012 236.014 1.00 86.31  ? 311 ILE E O   1 
ATOM   13687 C  CB  . ILE E 1 311 ? 216.385 260.225 235.700 1.00 85.28  ? 311 ILE E CB  1 
ATOM   13688 C  CG1 . ILE E 1 311 ? 216.088 261.636 235.189 1.00 86.74  ? 311 ILE E CG1 1 
ATOM   13689 C  CG2 . ILE E 1 311 ? 217.844 259.868 235.457 1.00 92.37  ? 311 ILE E CG2 1 
ATOM   13690 C  CD1 . ILE E 1 311 ? 216.661 261.922 233.817 1.00 82.54  ? 311 ILE E CD1 1 
ATOM   13691 N  N   . ARG E 1 312 ? 216.884 257.466 234.151 1.00 94.52  ? 312 ARG E N   1 
ATOM   13692 C  CA  . ARG E 1 312 ? 217.649 256.226 234.142 1.00 100.05 ? 312 ARG E CA  1 
ATOM   13693 C  C   . ARG E 1 312 ? 219.104 256.540 234.466 1.00 101.96 ? 312 ARG E C   1 
ATOM   13694 O  O   . ARG E 1 312 ? 219.691 257.454 233.877 1.00 100.30 ? 312 ARG E O   1 
ATOM   13695 C  CB  . ARG E 1 312 ? 217.549 255.529 232.784 1.00 99.20  ? 312 ARG E CB  1 
ATOM   13696 C  CG  . ARG E 1 312 ? 216.130 255.213 232.338 1.00 99.80  ? 312 ARG E CG  1 
ATOM   13697 C  CD  . ARG E 1 312 ? 215.555 254.033 233.107 1.00 103.92 ? 312 ARG E CD  1 
ATOM   13698 N  NE  . ARG E 1 312 ? 216.139 252.768 232.676 1.00 109.87 ? 312 ARG E NE  1 
ATOM   13699 C  CZ  . ARG E 1 312 ? 216.980 252.043 233.401 1.00 111.81 ? 312 ARG E CZ  1 
ATOM   13700 N  NH1 . ARG E 1 312 ? 217.363 252.430 234.607 1.00 108.32 ? 312 ARG E NH1 1 
ATOM   13701 N  NH2 . ARG E 1 312 ? 217.449 250.902 232.904 1.00 110.29 ? 312 ARG E NH2 1 
ATOM   13702 N  N   . LEU E 1 313 ? 219.683 255.784 235.399 1.00 103.15 ? 313 LEU E N   1 
ATOM   13703 C  CA  . LEU E 1 313 ? 221.021 256.079 235.890 1.00 102.73 ? 313 LEU E CA  1 
ATOM   13704 C  C   . LEU E 1 313 ? 221.967 254.920 235.624 1.00 103.38 ? 313 LEU E C   1 
ATOM   13705 O  O   . LEU E 1 313 ? 221.606 253.762 235.872 1.00 102.82 ? 313 LEU E O   1 
ATOM   13706 C  CB  . LEU E 1 313 ? 220.985 256.382 237.392 1.00 103.34 ? 313 LEU E CB  1 
ATOM   13707 C  CG  . LEU E 1 313 ? 220.449 257.754 237.803 1.00 101.66 ? 313 LEU E CG  1 
ATOM   13708 C  CD1 . LEU E 1 313 ? 221.038 258.181 239.139 1.00 92.67  ? 313 LEU E CD1 1 
ATOM   13709 C  CD2 . LEU E 1 313 ? 220.747 258.787 236.729 1.00 97.04  ? 313 LEU E CD2 1 
ATOM   13710 N  N   . PRO E 1 314 ? 223.174 255.188 235.125 1.00 105.20 ? 314 PRO E N   1 
ATOM   13711 C  CA  . PRO E 1 314 ? 224.167 254.118 234.987 1.00 102.65 ? 314 PRO E CA  1 
ATOM   13712 C  C   . PRO E 1 314 ? 224.521 253.519 236.339 1.00 103.73 ? 314 PRO E C   1 
ATOM   13713 O  O   . PRO E 1 314 ? 224.410 254.168 237.381 1.00 101.64 ? 314 PRO E O   1 
ATOM   13714 C  CB  . PRO E 1 314 ? 225.371 254.828 234.358 1.00 98.50  ? 314 PRO E CB  1 
ATOM   13715 C  CG  . PRO E 1 314 ? 224.796 256.020 233.674 1.00 98.32  ? 314 PRO E CG  1 
ATOM   13716 C  CD  . PRO E 1 314 ? 223.619 256.447 234.503 1.00 101.45 ? 314 PRO E CD  1 
ATOM   13717 N  N   . GLU E 1 315 ? 224.947 252.257 236.310 1.00 106.76 ? 315 GLU E N   1 
ATOM   13718 C  CA  . GLU E 1 315 ? 225.275 251.535 237.534 1.00 107.97 ? 315 GLU E CA  1 
ATOM   13719 C  C   . GLU E 1 315 ? 226.252 252.325 238.393 1.00 105.44 ? 315 GLU E C   1 
ATOM   13720 O  O   . GLU E 1 315 ? 227.270 252.824 237.904 1.00 101.73 ? 315 GLU E O   1 
ATOM   13721 C  CB  . GLU E 1 315 ? 225.868 250.167 237.188 1.00 108.94 ? 315 GLU E CB  1 
ATOM   13722 C  CG  . GLU E 1 315 ? 226.315 249.359 238.396 1.00 112.16 ? 315 GLU E CG  1 
ATOM   13723 C  CD  . GLU E 1 315 ? 225.168 249.009 239.323 1.00 118.34 ? 315 GLU E CD  1 
ATOM   13724 O  OE1 . GLU E 1 315 ? 224.826 249.840 240.191 1.00 116.47 ? 315 GLU E OE1 1 
ATOM   13725 O  OE2 . GLU E 1 315 ? 224.610 247.901 239.185 1.00 116.74 ? 315 GLU E OE2 1 
ATOM   13726 N  N   . GLY E 1 316 ? 225.935 252.433 239.683 1.00 102.40 ? 316 GLY E N   1 
ATOM   13727 C  CA  . GLY E 1 316 ? 226.767 253.139 240.630 1.00 97.95  ? 316 GLY E CA  1 
ATOM   13728 C  C   . GLY E 1 316 ? 226.503 254.624 240.739 1.00 93.20  ? 316 GLY E C   1 
ATOM   13729 O  O   . GLY E 1 316 ? 227.024 255.261 241.664 1.00 88.56  ? 316 GLY E O   1 
ATOM   13730 N  N   . GLN E 1 317 ? 225.708 255.196 239.838 1.00 93.18  ? 317 GLN E N   1 
ATOM   13731 C  CA  . GLN E 1 317 ? 225.455 256.629 239.868 1.00 86.14  ? 317 GLN E CA  1 
ATOM   13732 C  C   . GLN E 1 317 ? 224.775 257.029 241.172 1.00 84.59  ? 317 GLN E C   1 
ATOM   13733 O  O   . GLN E 1 317 ? 223.841 256.368 241.636 1.00 86.03  ? 317 GLN E O   1 
ATOM   13734 C  CB  . GLN E 1 317 ? 224.590 257.039 238.676 1.00 87.95  ? 317 GLN E CB  1 
ATOM   13735 C  CG  . GLN E 1 317 ? 224.393 258.538 238.536 1.00 88.45  ? 317 GLN E CG  1 
ATOM   13736 C  CD  . GLN E 1 317 ? 224.815 259.055 237.176 1.00 91.29  ? 317 GLN E CD  1 
ATOM   13737 O  OE1 . GLN E 1 317 ? 225.220 258.284 236.306 1.00 94.13  ? 317 GLN E OE1 1 
ATOM   13738 N  NE2 . GLN E 1 317 ? 224.718 260.365 236.983 1.00 87.29  ? 317 GLN E NE2 1 
ATOM   13739 N  N   . ILE E 1 318 ? 225.257 258.118 241.767 1.00 83.38  ? 318 ILE E N   1 
ATOM   13740 C  CA  . ILE E 1 318 ? 224.694 258.674 242.991 1.00 83.54  ? 318 ILE E CA  1 
ATOM   13741 C  C   . ILE E 1 318 ? 224.360 260.137 242.741 1.00 78.89  ? 318 ILE E C   1 
ATOM   13742 O  O   . ILE E 1 318 ? 225.202 260.895 242.245 1.00 79.52  ? 318 ILE E O   1 
ATOM   13743 C  CB  . ILE E 1 318 ? 225.659 258.526 244.182 1.00 81.12  ? 318 ILE E CB  1 
ATOM   13744 C  CG1 . ILE E 1 318 ? 225.996 257.053 244.407 1.00 80.61  ? 318 ILE E CG1 1 
ATOM   13745 C  CG2 . ILE E 1 318 ? 225.051 259.125 245.440 1.00 71.49  ? 318 ILE E CG2 1 
ATOM   13746 C  CD1 . ILE E 1 318 ? 224.829 256.235 244.913 1.00 75.66  ? 318 ILE E CD1 1 
ATOM   13747 N  N   . MET E 1 319 ? 223.136 260.529 243.083 1.00 74.25  ? 319 MET E N   1 
ATOM   13748 C  CA  . MET E 1 319 ? 222.663 261.891 242.894 1.00 72.18  ? 319 MET E CA  1 
ATOM   13749 C  C   . MET E 1 319 ? 222.326 262.518 244.239 1.00 63.71  ? 319 MET E C   1 
ATOM   13750 O  O   . MET E 1 319 ? 221.992 261.821 245.202 1.00 59.80  ? 319 MET E O   1 
ATOM   13751 C  CB  . MET E 1 319 ? 221.431 261.935 241.984 1.00 70.45  ? 319 MET E CB  1 
ATOM   13752 C  CG  . MET E 1 319 ? 221.756 262.013 240.505 1.00 76.32  ? 319 MET E CG  1 
ATOM   13753 S  SD  . MET E 1 319 ? 220.374 261.500 239.468 1.00 105.29 ? 319 MET E SD  1 
ATOM   13754 C  CE  . MET E 1 319 ? 219.057 261.412 240.676 1.00 80.23  ? 319 MET E CE  1 
ATOM   13755 N  N   . ASP E 1 320 ? 222.418 263.842 244.294 1.00 56.69  ? 320 ASP E N   1 
ATOM   13756 C  CA  . ASP E 1 320 ? 222.074 264.606 245.483 1.00 48.22  ? 320 ASP E CA  1 
ATOM   13757 C  C   . ASP E 1 320 ? 220.652 265.137 245.356 1.00 45.56  ? 320 ASP E C   1 
ATOM   13758 O  O   . ASP E 1 320 ? 220.236 265.579 244.281 1.00 50.32  ? 320 ASP E O   1 
ATOM   13759 C  CB  . ASP E 1 320 ? 223.054 265.761 245.694 1.00 44.04  ? 320 ASP E CB  1 
ATOM   13760 C  CG  . ASP E 1 320 ? 223.151 266.184 247.146 1.00 49.08  ? 320 ASP E CG  1 
ATOM   13761 O  OD1 . ASP E 1 320 ? 223.570 265.356 247.979 1.00 53.39  ? 320 ASP E OD1 1 
ATOM   13762 O  OD2 . ASP E 1 320 ? 222.807 267.344 247.454 1.00 47.61  ? 320 ASP E OD2 1 
ATOM   13763 N  N   . ASP E 1 321 ? 219.911 265.085 246.457 1.00 41.86  ? 321 ASP E N   1 
ATOM   13764 C  CA  . ASP E 1 321 ? 218.506 265.455 246.460 1.00 38.74  ? 321 ASP E CA  1 
ATOM   13765 C  C   . ASP E 1 321 ? 218.332 266.971 246.468 1.00 33.45  ? 321 ASP E C   1 
ATOM   13766 O  O   . ASP E 1 321 ? 219.231 267.728 246.842 1.00 34.57  ? 321 ASP E O   1 
ATOM   13767 C  CB  . ASP E 1 321 ? 217.800 264.850 247.674 1.00 38.65  ? 321 ASP E CB  1 
ATOM   13768 C  CG  . ASP E 1 321 ? 217.952 263.346 247.747 1.00 51.17  ? 321 ASP E CG  1 
ATOM   13769 O  OD1 . ASP E 1 321 ? 217.226 262.638 247.019 1.00 51.95  ? 321 ASP E OD1 1 
ATOM   13770 O  OD2 . ASP E 1 321 ? 218.796 262.871 248.534 1.00 56.78  ? 321 ASP E OD2 1 
ATOM   13771 N  N   . PHE E 1 322 ? 217.148 267.407 246.043 1.00 32.03  ? 322 PHE E N   1 
ATOM   13772 C  CA  . PHE E 1 322 ? 216.762 268.803 246.193 1.00 23.61  ? 322 PHE E CA  1 
ATOM   13773 C  C   . PHE E 1 322 ? 216.631 269.155 247.668 1.00 22.55  ? 322 PHE E C   1 
ATOM   13774 O  O   . PHE E 1 322 ? 216.186 268.340 248.480 1.00 28.43  ? 322 PHE E O   1 
ATOM   13775 C  CB  . PHE E 1 322 ? 215.441 269.073 245.474 1.00 24.31  ? 322 PHE E CB  1 
ATOM   13776 C  CG  . PHE E 1 322 ? 215.524 268.951 243.983 1.00 25.54  ? 322 PHE E CG  1 
ATOM   13777 C  CD1 . PHE E 1 322 ? 215.998 269.999 243.217 1.00 26.86  ? 322 PHE E CD1 1 
ATOM   13778 C  CD2 . PHE E 1 322 ? 215.123 267.790 243.347 1.00 27.67  ? 322 PHE E CD2 1 
ATOM   13779 C  CE1 . PHE E 1 322 ? 216.074 269.890 241.845 1.00 27.80  ? 322 PHE E CE1 1 
ATOM   13780 C  CE2 . PHE E 1 322 ? 215.194 267.677 241.977 1.00 25.51  ? 322 PHE E CE2 1 
ATOM   13781 C  CZ  . PHE E 1 322 ? 215.671 268.728 241.224 1.00 27.05  ? 322 PHE E CZ  1 
ATOM   13782 N  N   . ARG E 1 323 ? 217.016 270.380 248.016 1.00 20.24  ? 323 ARG E N   1 
ATOM   13783 C  CA  . ARG E 1 323 ? 217.005 270.802 249.408 1.00 16.73  ? 323 ARG E CA  1 
ATOM   13784 C  C   . ARG E 1 323 ? 216.831 272.310 249.481 1.00 15.75  ? 323 ARG E C   1 
ATOM   13785 O  O   . ARG E 1 323 ? 216.998 273.024 248.491 1.00 21.61  ? 323 ARG E O   1 
ATOM   13786 C  CB  . ARG E 1 323 ? 218.295 270.396 250.127 1.00 15.65  ? 323 ARG E CB  1 
ATOM   13787 C  CG  . ARG E 1 323 ? 219.539 270.719 249.328 1.00 18.44  ? 323 ARG E CG  1 
ATOM   13788 C  CD  . ARG E 1 323 ? 220.804 270.454 250.112 1.00 18.47  ? 323 ARG E CD  1 
ATOM   13789 N  NE  . ARG E 1 323 ? 221.984 270.719 249.300 1.00 26.21  ? 323 ARG E NE  1 
ATOM   13790 C  CZ  . ARG E 1 323 ? 222.686 271.842 249.350 1.00 25.66  ? 323 ARG E CZ  1 
ATOM   13791 N  NH1 . ARG E 1 323 ? 222.353 272.829 250.165 1.00 24.94  ? 323 ARG E NH1 1 
ATOM   13792 N  NH2 . ARG E 1 323 ? 223.745 271.981 248.559 1.00 22.00  ? 323 ARG E NH2 1 
ATOM   13793 N  N   . LEU E 1 324 ? 216.483 272.785 250.672 1.00 15.45  ? 324 LEU E N   1 
ATOM   13794 C  CA  . LEU E 1 324 ? 216.553 274.209 250.941 1.00 16.13  ? 324 LEU E CA  1 
ATOM   13795 C  C   . LEU E 1 324 ? 218.013 274.653 250.996 1.00 18.45  ? 324 LEU E C   1 
ATOM   13796 O  O   . LEU E 1 324 ? 218.881 273.905 251.453 1.00 22.16  ? 324 LEU E O   1 
ATOM   13797 C  CB  . LEU E 1 324 ? 215.862 274.548 252.258 1.00 14.96  ? 324 LEU E CB  1 
ATOM   13798 C  CG  . LEU E 1 324 ? 214.341 274.423 252.324 1.00 15.31  ? 324 LEU E CG  1 
ATOM   13799 C  CD1 . LEU E 1 324 ? 213.861 274.667 253.744 1.00 12.93  ? 324 LEU E CD1 1 
ATOM   13800 C  CD2 . LEU E 1 324 ? 213.678 275.386 251.358 1.00 13.73  ? 324 LEU E CD2 1 
ATOM   13801 N  N   . PRO E 1 325 ? 218.311 275.859 250.524 1.00 18.51  ? 325 PRO E N   1 
ATOM   13802 C  CA  . PRO E 1 325 ? 219.688 276.353 250.593 1.00 17.81  ? 325 PRO E CA  1 
ATOM   13803 C  C   . PRO E 1 325 ? 220.101 276.651 252.024 1.00 20.61  ? 325 PRO E C   1 
ATOM   13804 O  O   . PRO E 1 325 ? 219.275 276.970 252.882 1.00 24.52  ? 325 PRO E O   1 
ATOM   13805 C  CB  . PRO E 1 325 ? 219.645 277.634 249.755 1.00 16.26  ? 325 PRO E CB  1 
ATOM   13806 C  CG  . PRO E 1 325 ? 218.233 278.093 249.867 1.00 15.01  ? 325 PRO E CG  1 
ATOM   13807 C  CD  . PRO E 1 325 ? 217.400 276.842 249.915 1.00 15.18  ? 325 PRO E CD  1 
ATOM   13808 N  N   . THR E 1 326 ? 221.399 276.533 252.282 1.00 18.78  ? 326 THR E N   1 
ATOM   13809 C  CA  . THR E 1 326 ? 221.930 277.083 253.516 1.00 19.38  ? 326 THR E CA  1 
ATOM   13810 C  C   . THR E 1 326 ? 221.938 278.605 253.424 1.00 19.88  ? 326 THR E C   1 
ATOM   13811 O  O   . THR E 1 326 ? 221.936 279.186 252.336 1.00 24.07  ? 326 THR E O   1 
ATOM   13812 C  CB  . THR E 1 326 ? 223.342 276.563 253.789 1.00 19.42  ? 326 THR E CB  1 
ATOM   13813 O  OG1 . THR E 1 326 ? 224.225 276.998 252.750 1.00 24.42  ? 326 THR E OG1 1 
ATOM   13814 C  CG2 . THR E 1 326 ? 223.350 275.048 253.849 1.00 20.56  ? 326 THR E CG2 1 
ATOM   13815 N  N   . GLU E 1 327 ? 221.938 279.259 254.584 1.00 15.16  ? 327 GLU E N   1 
ATOM   13816 C  CA  . GLU E 1 327 ? 221.913 280.716 254.563 1.00 17.86  ? 327 GLU E CA  1 
ATOM   13817 C  C   . GLU E 1 327 ? 223.192 281.282 253.961 1.00 22.41  ? 327 GLU E C   1 
ATOM   13818 O  O   . GLU E 1 327 ? 223.155 282.328 253.303 1.00 27.74  ? 327 GLU E O   1 
ATOM   13819 C  CB  . GLU E 1 327 ? 221.671 281.264 255.969 1.00 17.53  ? 327 GLU E CB  1 
ATOM   13820 C  CG  . GLU E 1 327 ? 222.846 281.157 256.913 1.00 20.39  ? 327 GLU E CG  1 
ATOM   13821 C  CD  . GLU E 1 327 ? 222.721 282.112 258.080 1.00 30.58  ? 327 GLU E CD  1 
ATOM   13822 O  OE1 . GLU E 1 327 ? 222.408 283.297 257.845 1.00 29.75  ? 327 GLU E OE1 1 
ATOM   13823 O  OE2 . GLU E 1 327 ? 222.931 281.680 259.232 1.00 36.37  ? 327 GLU E OE2 1 
ATOM   13824 N  N   . ALA E 1 328 ? 224.323 280.598 254.150 1.00 17.94  ? 328 ALA E N   1 
ATOM   13825 C  CA  . ALA E 1 328 ? 225.557 281.007 253.486 1.00 17.42  ? 328 ALA E CA  1 
ATOM   13826 C  C   . ALA E 1 328 ? 225.432 280.881 251.972 1.00 19.80  ? 328 ALA E C   1 
ATOM   13827 O  O   . ALA E 1 328 ? 225.817 281.790 251.227 1.00 23.80  ? 328 ALA E O   1 
ATOM   13828 C  CB  . ALA E 1 328 ? 226.729 280.174 254.004 1.00 15.64  ? 328 ALA E CB  1 
ATOM   13829 N  N   . GLU E 1 329 ? 224.885 279.758 251.497 1.00 16.71  ? 329 GLU E N   1 
ATOM   13830 C  CA  . GLU E 1 329 ? 224.673 279.594 250.063 1.00 14.83  ? 329 GLU E CA  1 
ATOM   13831 C  C   . GLU E 1 329 ? 223.730 280.657 249.526 1.00 19.08  ? 329 GLU E C   1 
ATOM   13832 O  O   . GLU E 1 329 ? 223.966 281.225 248.452 1.00 22.83  ? 329 GLU E O   1 
ATOM   13833 C  CB  . GLU E 1 329 ? 224.114 278.205 249.762 1.00 17.28  ? 329 GLU E CB  1 
ATOM   13834 C  CG  . GLU E 1 329 ? 225.129 277.090 249.794 1.00 16.45  ? 329 GLU E CG  1 
ATOM   13835 C  CD  . GLU E 1 329 ? 224.482 275.727 249.668 1.00 21.77  ? 329 GLU E CD  1 
ATOM   13836 O  OE1 . GLU E 1 329 ? 223.350 275.556 250.162 1.00 26.58  ? 329 GLU E OE1 1 
ATOM   13837 O  OE2 . GLU E 1 329 ? 225.104 274.827 249.070 1.00 31.10  ? 329 GLU E OE2 1 
ATOM   13838 N  N   . TRP E 1 330 ? 222.647 280.931 250.254 1.00 16.40  ? 330 TRP E N   1 
ATOM   13839 C  CA  . TRP E 1 330 ? 221.685 281.925 249.801 1.00 16.08  ? 330 TRP E CA  1 
ATOM   13840 C  C   . TRP E 1 330 ? 222.326 283.303 249.712 1.00 17.32  ? 330 TRP E C   1 
ATOM   13841 O  O   . TRP E 1 330 ? 222.146 284.018 248.721 1.00 20.35  ? 330 TRP E O   1 
ATOM   13842 C  CB  . TRP E 1 330 ? 220.473 281.949 250.733 1.00 15.88  ? 330 TRP E CB  1 
ATOM   13843 C  CG  . TRP E 1 330 ? 219.359 282.787 250.202 1.00 15.68  ? 330 TRP E CG  1 
ATOM   13844 C  CD1 . TRP E 1 330 ? 218.261 282.352 249.525 1.00 15.67  ? 330 TRP E CD1 1 
ATOM   13845 C  CD2 . TRP E 1 330 ? 219.241 284.210 250.288 1.00 16.38  ? 330 TRP E CD2 1 
ATOM   13846 N  NE1 . TRP E 1 330 ? 217.463 283.415 249.188 1.00 17.89  ? 330 TRP E NE1 1 
ATOM   13847 C  CE2 . TRP E 1 330 ? 218.043 284.568 249.645 1.00 15.56  ? 330 TRP E CE2 1 
ATOM   13848 C  CE3 . TRP E 1 330 ? 220.030 285.217 250.851 1.00 14.97  ? 330 TRP E CE3 1 
ATOM   13849 C  CZ2 . TRP E 1 330 ? 217.616 285.887 249.547 1.00 13.98  ? 330 TRP E CZ2 1 
ATOM   13850 C  CZ3 . TRP E 1 330 ? 219.605 286.523 250.752 1.00 14.43  ? 330 TRP E CZ3 1 
ATOM   13851 C  CH2 . TRP E 1 330 ? 218.410 286.847 250.106 1.00 14.96  ? 330 TRP E CH2 1 
ATOM   13852 N  N   . GLU E 1 331 ? 223.077 283.699 250.741 1.00 17.76  ? 331 GLU E N   1 
ATOM   13853 C  CA  . GLU E 1 331 ? 223.710 285.012 250.703 1.00 19.73  ? 331 GLU E CA  1 
ATOM   13854 C  C   . GLU E 1 331 ? 224.730 285.095 249.576 1.00 19.86  ? 331 GLU E C   1 
ATOM   13855 O  O   . GLU E 1 331 ? 224.823 286.118 248.889 1.00 27.60  ? 331 GLU E O   1 
ATOM   13856 C  CB  . GLU E 1 331 ? 224.365 285.336 252.045 1.00 20.21  ? 331 GLU E CB  1 
ATOM   13857 C  CG  . GLU E 1 331 ? 224.677 286.818 252.210 1.00 23.95  ? 331 GLU E CG  1 
ATOM   13858 C  CD  . GLU E 1 331 ? 225.135 287.183 253.608 1.00 31.13  ? 331 GLU E CD  1 
ATOM   13859 O  OE1 . GLU E 1 331 ? 224.773 286.470 254.566 1.00 36.03  ? 331 GLU E OE1 1 
ATOM   13860 O  OE2 . GLU E 1 331 ? 225.849 288.196 253.751 1.00 33.35  ? 331 GLU E OE2 1 
ATOM   13861 N  N   . TYR E 1 332 ? 225.506 284.029 249.369 1.00 17.20  ? 332 TYR E N   1 
ATOM   13862 C  CA  . TYR E 1 332 ? 226.498 284.044 248.301 1.00 17.27  ? 332 TYR E CA  1 
ATOM   13863 C  C   . TYR E 1 332 ? 225.835 284.166 246.934 1.00 18.75  ? 332 TYR E C   1 
ATOM   13864 O  O   . TYR E 1 332 ? 226.310 284.911 246.070 1.00 20.06  ? 332 TYR E O   1 
ATOM   13865 C  CB  . TYR E 1 332 ? 227.363 282.785 248.373 1.00 19.12  ? 332 TYR E CB  1 
ATOM   13866 C  CG  . TYR E 1 332 ? 228.237 282.564 247.160 1.00 20.34  ? 332 TYR E CG  1 
ATOM   13867 C  CD1 . TYR E 1 332 ? 229.519 283.095 247.099 1.00 17.44  ? 332 TYR E CD1 1 
ATOM   13868 C  CD2 . TYR E 1 332 ? 227.786 281.819 246.082 1.00 16.51  ? 332 TYR E CD2 1 
ATOM   13869 C  CE1 . TYR E 1 332 ? 230.319 282.897 245.994 1.00 16.34  ? 332 TYR E CE1 1 
ATOM   13870 C  CE2 . TYR E 1 332 ? 228.580 281.615 244.976 1.00 20.07  ? 332 TYR E CE2 1 
ATOM   13871 C  CZ  . TYR E 1 332 ? 229.845 282.154 244.937 1.00 17.54  ? 332 TYR E CZ  1 
ATOM   13872 O  OH  . TYR E 1 332 ? 230.633 281.949 243.831 1.00 22.24  ? 332 TYR E OH  1 
ATOM   13873 N  N   . ALA E 1 333 ? 224.734 283.442 246.719 1.00 19.80  ? 333 ALA E N   1 
ATOM   13874 C  CA  . ALA E 1 333 ? 224.058 283.496 245.428 1.00 15.85  ? 333 ALA E CA  1 
ATOM   13875 C  C   . ALA E 1 333 ? 223.362 284.836 245.215 1.00 19.06  ? 333 ALA E C   1 
ATOM   13876 O  O   . ALA E 1 333 ? 223.352 285.364 244.099 1.00 25.64  ? 333 ALA E O   1 
ATOM   13877 C  CB  . ALA E 1 333 ? 223.059 282.347 245.311 1.00 15.37  ? 333 ALA E CB  1 
ATOM   13878 N  N   . ALA E 1 334 ? 222.773 285.399 246.273 1.00 20.82  ? 334 ALA E N   1 
ATOM   13879 C  CA  . ALA E 1 334 ? 222.028 286.647 246.140 1.00 18.45  ? 334 ALA E CA  1 
ATOM   13880 C  C   . ALA E 1 334 ? 222.937 287.806 245.755 1.00 22.54  ? 334 ALA E C   1 
ATOM   13881 O  O   . ALA E 1 334 ? 222.547 288.669 244.961 1.00 21.39  ? 334 ALA E O   1 
ATOM   13882 C  CB  . ALA E 1 334 ? 221.290 286.959 247.440 1.00 14.53  ? 334 ALA E CB  1 
ATOM   13883 N  N   . ARG E 1 335 ? 224.145 287.846 246.310 1.00 20.35  ? 335 ARG E N   1 
ATOM   13884 C  CA  . ARG E 1 335 ? 225.084 288.927 246.057 1.00 18.56  ? 335 ARG E CA  1 
ATOM   13885 C  C   . ARG E 1 335 ? 226.045 288.620 244.916 1.00 23.35  ? 335 ARG E C   1 
ATOM   13886 O  O   . ARG E 1 335 ? 227.023 289.349 244.735 1.00 25.73  ? 335 ARG E O   1 
ATOM   13887 C  CB  . ARG E 1 335 ? 225.867 289.250 247.331 1.00 21.92  ? 335 ARG E CB  1 
ATOM   13888 C  CG  . ARG E 1 335 ? 224.995 289.739 248.473 1.00 22.84  ? 335 ARG E CG  1 
ATOM   13889 C  CD  . ARG E 1 335 ? 225.690 289.587 249.812 1.00 20.51  ? 335 ARG E CD  1 
ATOM   13890 N  NE  . ARG E 1 335 ? 226.878 290.425 249.897 1.00 26.10  ? 335 ARG E NE  1 
ATOM   13891 C  CZ  . ARG E 1 335 ? 227.701 290.456 250.935 1.00 29.78  ? 335 ARG E CZ  1 
ATOM   13892 N  NH1 . ARG E 1 335 ? 227.493 289.706 252.004 1.00 31.12  ? 335 ARG E NH1 1 
ATOM   13893 N  NH2 . ARG E 1 335 ? 228.757 291.264 250.902 1.00 31.58  ? 335 ARG E NH2 1 
ATOM   13894 N  N   . MET E 1 336 ? 225.788 287.562 244.146 1.00 23.47  ? 336 MET E N   1 
ATOM   13895 C  CA  . MET E 1 336 ? 226.589 287.230 242.970 1.00 21.84  ? 336 MET E CA  1 
ATOM   13896 C  C   . MET E 1 336 ? 228.042 286.942 243.334 1.00 24.19  ? 336 MET E C   1 
ATOM   13897 O  O   . MET E 1 336 ? 228.952 287.191 242.541 1.00 27.85  ? 336 MET E O   1 
ATOM   13898 C  CB  . MET E 1 336 ? 226.516 288.343 241.922 1.00 22.91  ? 336 MET E CB  1 
ATOM   13899 C  CG  . MET E 1 336 ? 225.114 288.614 241.411 1.00 26.35  ? 336 MET E CG  1 
ATOM   13900 S  SD  . MET E 1 336 ? 224.467 290.214 241.934 1.00 41.49  ? 336 MET E SD  1 
ATOM   13901 C  CE  . MET E 1 336 ? 225.438 291.323 240.922 1.00 31.06  ? 336 MET E CE  1 
ATOM   13902 N  N   . GLY E 1 337 ? 228.269 286.415 244.535 1.00 23.39  ? 337 GLY E N   1 
ATOM   13903 C  CA  . GLY E 1 337 ? 229.613 286.074 244.958 1.00 19.73  ? 337 GLY E CA  1 
ATOM   13904 C  C   . GLY E 1 337 ? 230.556 287.247 245.075 1.00 25.75  ? 337 GLY E C   1 
ATOM   13905 O  O   . GLY E 1 337 ? 231.773 287.054 245.070 1.00 34.24  ? 337 GLY E O   1 
ATOM   13906 N  N   . ASP E 1 338 ? 230.029 288.464 245.181 1.00 27.61  ? 338 ASP E N   1 
ATOM   13907 C  CA  . ASP E 1 338 ? 230.833 289.669 245.315 1.00 29.25  ? 338 ASP E CA  1 
ATOM   13908 C  C   . ASP E 1 338 ? 230.527 290.323 246.655 1.00 31.69  ? 338 ASP E C   1 
ATOM   13909 O  O   . ASP E 1 338 ? 229.359 290.544 246.988 1.00 32.32  ? 338 ASP E O   1 
ATOM   13910 C  CB  . ASP E 1 338 ? 230.554 290.643 244.166 1.00 34.43  ? 338 ASP E CB  1 
ATOM   13911 C  CG  . ASP E 1 338 ? 231.592 291.744 244.066 1.00 45.62  ? 338 ASP E CG  1 
ATOM   13912 O  OD1 . ASP E 1 338 ? 232.036 292.245 245.119 1.00 45.80  ? 338 ASP E OD1 1 
ATOM   13913 O  OD2 . ASP E 1 338 ? 231.960 292.113 242.932 1.00 55.02  ? 338 ASP E OD2 1 
ATOM   13914 N  N   . SER E 1 339 ? 231.576 290.630 247.420 1.00 31.89  ? 339 SER E N   1 
ATOM   13915 C  CA  . SER E 1 339 ? 231.406 291.257 248.724 1.00 30.56  ? 339 SER E CA  1 
ATOM   13916 C  C   . SER E 1 339 ? 231.116 292.749 248.635 1.00 38.44  ? 339 SER E C   1 
ATOM   13917 O  O   . SER E 1 339 ? 230.779 293.359 249.655 1.00 41.78  ? 339 SER E O   1 
ATOM   13918 C  CB  . SER E 1 339 ? 232.650 291.031 249.586 1.00 29.31  ? 339 SER E CB  1 
ATOM   13919 O  OG  . SER E 1 339 ? 233.113 289.699 249.471 1.00 32.60  ? 339 SER E OG  1 
ATOM   13920 N  N   . ASN E 1 340 ? 231.237 293.348 247.451 1.00 38.20  ? 340 ASN E N   1 
ATOM   13921 C  CA  . ASN E 1 340 ? 230.940 294.763 247.276 1.00 34.62  ? 340 ASN E CA  1 
ATOM   13922 C  C   . ASN E 1 340 ? 229.454 295.039 247.106 1.00 36.28  ? 340 ASN E C   1 
ATOM   13923 O  O   . ASN E 1 340 ? 229.062 296.209 247.050 1.00 42.70  ? 340 ASN E O   1 
ATOM   13924 C  CB  . ASN E 1 340 ? 231.701 295.313 246.068 1.00 41.28  ? 340 ASN E CB  1 
ATOM   13925 C  CG  . ASN E 1 340 ? 233.199 295.343 246.287 1.00 44.78  ? 340 ASN E CG  1 
ATOM   13926 O  OD1 . ASN E 1 340 ? 233.671 295.504 247.411 1.00 50.31  ? 340 ASN E OD1 1 
ATOM   13927 N  ND2 . ASN E 1 340 ? 233.957 295.187 245.209 1.00 47.56  ? 340 ASN E ND2 1 
ATOM   13928 N  N   . ASN E 1 341 ? 228.625 294.004 247.028 1.00 35.36  ? 341 ASN E N   1 
ATOM   13929 C  CA  . ASN E 1 341 ? 227.195 294.154 246.799 1.00 28.94  ? 341 ASN E CA  1 
ATOM   13930 C  C   . ASN E 1 341 ? 226.443 294.036 248.115 1.00 28.26  ? 341 ASN E C   1 
ATOM   13931 O  O   . ASN E 1 341 ? 226.656 293.085 248.873 1.00 32.01  ? 341 ASN E O   1 
ATOM   13932 C  CB  . ASN E 1 341 ? 226.686 293.099 245.817 1.00 28.87  ? 341 ASN E CB  1 
ATOM   13933 C  CG  . ASN E 1 341 ? 227.270 293.259 244.433 1.00 32.77  ? 341 ASN E CG  1 
ATOM   13934 O  OD1 . ASN E 1 341 ? 227.496 294.374 243.967 1.00 40.88  ? 341 ASN E OD1 1 
ATOM   13935 N  ND2 . ASN E 1 341 ? 227.518 292.141 243.766 1.00 33.39  ? 341 ASN E ND2 1 
ATOM   13936 N  N   . LYS E 1 342 ? 225.566 295.001 248.385 1.00 29.08  ? 342 LYS E N   1 
ATOM   13937 C  CA  . LYS E 1 342 ? 224.640 294.882 249.501 1.00 28.21  ? 342 LYS E CA  1 
ATOM   13938 C  C   . LYS E 1 342 ? 223.291 294.325 249.078 1.00 27.37  ? 342 LYS E C   1 
ATOM   13939 O  O   . LYS E 1 342 ? 222.549 293.816 249.925 1.00 31.49  ? 342 LYS E O   1 
ATOM   13940 C  CB  . LYS E 1 342 ? 224.433 296.239 250.179 1.00 27.48  ? 342 LYS E CB  1 
ATOM   13941 C  CG  . LYS E 1 342 ? 225.465 296.556 251.245 1.00 37.96  ? 342 LYS E CG  1 
ATOM   13942 C  CD  . LYS E 1 342 ? 225.140 297.857 251.954 1.00 52.59  ? 342 LYS E CD  1 
ATOM   13943 C  CE  . LYS E 1 342 ? 223.711 298.291 251.672 1.00 44.16  ? 342 LYS E CE  1 
ATOM   13944 N  NZ  . LYS E 1 342 ? 223.315 299.454 252.509 1.00 42.31  ? 342 LYS E NZ  1 
ATOM   13945 N  N   . TYR E 1 343 ? 222.965 294.404 247.796 1.00 24.70  ? 343 TYR E N   1 
ATOM   13946 C  CA  . TYR E 1 343 ? 221.706 293.904 247.271 1.00 24.37  ? 343 TYR E CA  1 
ATOM   13947 C  C   . TYR E 1 343 ? 221.991 292.963 246.109 1.00 25.56  ? 343 TYR E C   1 
ATOM   13948 O  O   . TYR E 1 343 ? 223.155 292.791 245.726 1.00 28.58  ? 343 TYR E O   1 
ATOM   13949 C  CB  . TYR E 1 343 ? 220.814 295.060 246.820 1.00 24.61  ? 343 TYR E CB  1 
ATOM   13950 C  CG  . TYR E 1 343 ? 220.480 296.052 247.911 1.00 26.18  ? 343 TYR E CG  1 
ATOM   13951 C  CD1 . TYR E 1 343 ? 219.490 295.780 248.844 1.00 25.79  ? 343 TYR E CD1 1 
ATOM   13952 C  CD2 . TYR E 1 343 ? 221.146 297.267 247.999 1.00 25.54  ? 343 TYR E CD2 1 
ATOM   13953 C  CE1 . TYR E 1 343 ? 219.179 296.684 249.837 1.00 25.99  ? 343 TYR E CE1 1 
ATOM   13954 C  CE2 . TYR E 1 343 ? 220.840 298.177 248.987 1.00 30.88  ? 343 TYR E CE2 1 
ATOM   13955 C  CZ  . TYR E 1 343 ? 219.856 297.881 249.904 1.00 32.45  ? 343 TYR E CZ  1 
ATOM   13956 O  OH  . TYR E 1 343 ? 219.550 298.788 250.893 1.00 31.78  ? 343 TYR E OH  1 
ATOM   13957 N  N   . PRO E 1 344 ? 220.974 292.327 245.533 1.00 26.15  ? 344 PRO E N   1 
ATOM   13958 C  CA  . PRO E 1 344 ? 221.212 291.503 244.341 1.00 25.02  ? 344 PRO E CA  1 
ATOM   13959 C  C   . PRO E 1 344 ? 221.315 292.343 243.078 1.00 24.03  ? 344 PRO E C   1 
ATOM   13960 O  O   . PRO E 1 344 ? 220.732 292.005 242.045 1.00 27.93  ? 344 PRO E O   1 
ATOM   13961 C  CB  . PRO E 1 344 ? 219.991 290.572 244.303 1.00 20.45  ? 344 PRO E CB  1 
ATOM   13962 C  CG  . PRO E 1 344 ? 219.302 290.746 245.630 1.00 18.21  ? 344 PRO E CG  1 
ATOM   13963 C  CD  . PRO E 1 344 ? 219.619 292.132 246.069 1.00 20.88  ? 344 PRO E CD  1 
ATOM   13964 N  N   . TRP E 1 345 ? 222.060 293.443 243.157 1.00 24.05  ? 345 TRP E N   1 
ATOM   13965 C  CA  . TRP E 1 345 ? 222.336 294.282 242.001 1.00 26.34  ? 345 TRP E CA  1 
ATOM   13966 C  C   . TRP E 1 345 ? 223.573 295.115 242.299 1.00 33.17  ? 345 TRP E C   1 
ATOM   13967 O  O   . TRP E 1 345 ? 223.895 295.377 243.460 1.00 34.56  ? 345 TRP E O   1 
ATOM   13968 C  CB  . TRP E 1 345 ? 221.145 295.182 241.641 1.00 25.34  ? 345 TRP E CB  1 
ATOM   13969 C  CG  . TRP E 1 345 ? 220.508 295.883 242.806 1.00 24.40  ? 345 TRP E CG  1 
ATOM   13970 C  CD1 . TRP E 1 345 ? 220.962 297.003 243.437 1.00 23.99  ? 345 TRP E CD1 1 
ATOM   13971 C  CD2 . TRP E 1 345 ? 219.290 295.518 243.465 1.00 25.53  ? 345 TRP E CD2 1 
ATOM   13972 N  NE1 . TRP E 1 345 ? 220.108 297.354 244.452 1.00 23.74  ? 345 TRP E NE1 1 
ATOM   13973 C  CE2 . TRP E 1 345 ? 219.073 296.458 244.491 1.00 25.52  ? 345 TRP E CE2 1 
ATOM   13974 C  CE3 . TRP E 1 345 ? 218.365 294.485 243.291 1.00 20.34  ? 345 TRP E CE3 1 
ATOM   13975 C  CZ2 . TRP E 1 345 ? 217.971 296.397 245.337 1.00 23.20  ? 345 TRP E CZ2 1 
ATOM   13976 C  CZ3 . TRP E 1 345 ? 217.273 294.427 244.130 1.00 21.05  ? 345 TRP E CZ3 1 
ATOM   13977 C  CH2 . TRP E 1 345 ? 217.084 295.376 245.142 1.00 22.78  ? 345 TRP E CH2 1 
ATOM   13978 N  N   . SER E 1 346 ? 224.264 295.522 241.233 1.00 38.69  ? 346 SER E N   1 
ATOM   13979 C  CA  . SER E 1 346 ? 225.552 296.189 241.398 1.00 41.49  ? 346 SER E CA  1 
ATOM   13980 C  C   . SER E 1 346 ? 225.406 297.529 242.106 1.00 42.79  ? 346 SER E C   1 
ATOM   13981 O  O   . SER E 1 346 ? 226.196 297.855 243.001 1.00 43.59  ? 346 SER E O   1 
ATOM   13982 C  CB  . SER E 1 346 ? 226.220 296.377 240.037 1.00 44.20  ? 346 SER E CB  1 
ATOM   13983 O  OG  . SER E 1 346 ? 225.659 297.482 239.350 1.00 52.23  ? 346 SER E OG  1 
ATOM   13984 N  N   . THR E 1 347 ? 224.409 298.318 241.724 1.00 42.66  ? 347 THR E N   1 
ATOM   13985 C  CA  . THR E 1 347 ? 224.282 299.663 242.263 1.00 46.72  ? 347 THR E CA  1 
ATOM   13986 C  C   . THR E 1 347 ? 223.895 299.627 243.737 1.00 48.04  ? 347 THR E C   1 
ATOM   13987 O  O   . THR E 1 347 ? 223.263 298.683 244.218 1.00 48.95  ? 347 THR E O   1 
ATOM   13988 C  CB  . THR E 1 347 ? 223.245 300.463 241.475 1.00 51.76  ? 347 THR E CB  1 
ATOM   13989 O  OG1 . THR E 1 347 ? 223.508 301.863 241.625 1.00 58.59  ? 347 THR E OG1 1 
ATOM   13990 C  CG2 . THR E 1 347 ? 221.845 300.162 241.982 1.00 44.91  ? 347 THR E CG2 1 
ATOM   13991 N  N   . GLU E 1 348 ? 224.295 300.673 244.459 1.00 52.53  ? 348 GLU E N   1 
ATOM   13992 C  CA  . GLU E 1 348 ? 223.897 300.842 245.849 1.00 51.43  ? 348 GLU E CA  1 
ATOM   13993 C  C   . GLU E 1 348 ? 222.498 301.426 245.991 1.00 51.72  ? 348 GLU E C   1 
ATOM   13994 O  O   . GLU E 1 348 ? 221.933 301.380 247.089 1.00 47.31  ? 348 GLU E O   1 
ATOM   13995 C  CB  . GLU E 1 348 ? 224.905 301.740 246.571 1.00 56.20  ? 348 GLU E CB  1 
ATOM   13996 C  CG  . GLU E 1 348 ? 225.621 301.069 247.727 1.00 55.39  ? 348 GLU E CG  1 
ATOM   13997 C  CD  . GLU E 1 348 ? 224.681 300.679 248.847 1.00 56.98  ? 348 GLU E CD  1 
ATOM   13998 O  OE1 . GLU E 1 348 ? 223.686 301.399 249.070 1.00 57.99  ? 348 GLU E OE1 1 
ATOM   13999 O  OE2 . GLU E 1 348 ? 224.939 299.649 249.503 1.00 58.54  ? 348 GLU E OE2 1 
ATOM   14000 N  N   . ASP E 1 349 ? 221.933 301.967 244.916 1.00 50.77  ? 349 ASP E N   1 
ATOM   14001 C  CA  . ASP E 1 349 ? 220.606 302.557 244.954 1.00 44.95  ? 349 ASP E CA  1 
ATOM   14002 C  C   . ASP E 1 349 ? 219.534 301.482 244.807 1.00 44.65  ? 349 ASP E C   1 
ATOM   14003 O  O   . ASP E 1 349 ? 219.779 300.383 244.303 1.00 47.31  ? 349 ASP E O   1 
ATOM   14004 C  CB  . ASP E 1 349 ? 220.452 303.599 243.846 1.00 52.65  ? 349 ASP E CB  1 
ATOM   14005 C  CG  . ASP E 1 349 ? 221.526 304.667 243.896 1.00 64.11  ? 349 ASP E CG  1 
ATOM   14006 O  OD1 . ASP E 1 349 ? 221.571 305.419 244.893 1.00 67.22  ? 349 ASP E OD1 1 
ATOM   14007 O  OD2 . ASP E 1 349 ? 222.322 304.756 242.938 1.00 64.62  ? 349 ASP E OD2 1 
ATOM   14008 N  N   . LEU E 1 350 ? 218.327 301.816 245.257 1.00 40.55  ? 350 LEU E N   1 
ATOM   14009 C  CA  . LEU E 1 350 ? 217.185 300.918 245.163 1.00 35.92  ? 350 LEU E CA  1 
ATOM   14010 C  C   . LEU E 1 350 ? 216.353 301.145 243.908 1.00 35.26  ? 350 LEU E C   1 
ATOM   14011 O  O   . LEU E 1 350 ? 215.341 300.463 243.722 1.00 30.95  ? 350 LEU E O   1 
ATOM   14012 C  CB  . LEU E 1 350 ? 216.300 301.061 246.405 1.00 30.41  ? 350 LEU E CB  1 
ATOM   14013 C  CG  . LEU E 1 350 ? 216.915 300.578 247.720 1.00 31.11  ? 350 LEU E CG  1 
ATOM   14014 C  CD1 . LEU E 1 350 ? 216.648 301.573 248.837 1.00 36.78  ? 350 LEU E CD1 1 
ATOM   14015 C  CD2 . LEU E 1 350 ? 216.389 299.200 248.086 1.00 26.70  ? 350 LEU E CD2 1 
ATOM   14016 N  N   . ARG E 1 351 ? 216.752 302.079 243.048 1.00 36.04  ? 351 ARG E N   1 
ATOM   14017 C  CA  . ARG E 1 351 ? 216.038 302.358 241.812 1.00 35.82  ? 351 ARG E CA  1 
ATOM   14018 C  C   . ARG E 1 351 ? 217.036 302.484 240.673 1.00 40.49  ? 351 ARG E C   1 
ATOM   14019 O  O   . ARG E 1 351 ? 218.237 302.660 240.887 1.00 49.06  ? 351 ARG E O   1 
ATOM   14020 C  CB  . ARG E 1 351 ? 215.199 303.638 241.913 1.00 35.24  ? 351 ARG E CB  1 
ATOM   14021 C  CG  . ARG E 1 351 ? 214.324 303.708 243.144 1.00 29.76  ? 351 ARG E CG  1 
ATOM   14022 C  CD  . ARG E 1 351 ? 214.045 305.145 243.528 1.00 30.16  ? 351 ARG E CD  1 
ATOM   14023 N  NE  . ARG E 1 351 ? 212.825 305.643 242.906 1.00 34.55  ? 351 ARG E NE  1 
ATOM   14024 C  CZ  . ARG E 1 351 ? 211.943 306.424 243.513 1.00 38.50  ? 351 ARG E CZ  1 
ATOM   14025 N  NH1 . ARG E 1 351 ? 212.112 306.815 244.764 1.00 35.35  ? 351 ARG E NH1 1 
ATOM   14026 N  NH2 . ARG E 1 351 ? 210.861 306.818 242.848 1.00 36.86  ? 351 ARG E NH2 1 
ATOM   14027 N  N   . THR E 1 352 ? 216.522 302.380 239.452 1.00 42.83  ? 352 THR E N   1 
ATOM   14028 C  CA  . THR E 1 352 ? 217.338 302.570 238.262 1.00 49.10  ? 352 THR E CA  1 
ATOM   14029 C  C   . THR E 1 352 ? 217.570 304.064 238.049 1.00 53.40  ? 352 THR E C   1 
ATOM   14030 O  O   . THR E 1 352 ? 217.195 304.902 238.874 1.00 54.95  ? 352 THR E O   1 
ATOM   14031 C  CB  . THR E 1 352 ? 216.676 301.924 237.049 1.00 48.29  ? 352 THR E CB  1 
ATOM   14032 O  OG1 . THR E 1 352 ? 215.449 302.604 236.756 1.00 52.59  ? 352 THR E OG1 1 
ATOM   14033 C  CG2 . THR E 1 352 ? 216.386 300.459 237.315 1.00 43.04  ? 352 THR E CG2 1 
ATOM   14034 N  N   . GLY E 1 353 ? 218.202 304.416 236.929 1.00 57.38  ? 353 GLY E N   1 
ATOM   14035 C  CA  . GLY E 1 353 ? 218.366 305.817 236.590 1.00 53.82  ? 353 GLY E CA  1 
ATOM   14036 C  C   . GLY E 1 353 ? 217.065 306.517 236.264 1.00 55.75  ? 353 GLY E C   1 
ATOM   14037 O  O   . GLY E 1 353 ? 216.991 307.746 236.369 1.00 58.22  ? 353 GLY E O   1 
ATOM   14038 N  N   . ARG E 1 354 ? 216.040 305.765 235.876 1.00 55.81  ? 354 ARG E N   1 
ATOM   14039 C  CA  . ARG E 1 354 ? 214.732 306.318 235.559 1.00 58.44  ? 354 ARG E CA  1 
ATOM   14040 C  C   . ARG E 1 354 ? 213.784 306.324 236.752 1.00 56.27  ? 354 ARG E C   1 
ATOM   14041 O  O   . ARG E 1 354 ? 212.637 306.761 236.612 1.00 54.10  ? 354 ARG E O   1 
ATOM   14042 C  CB  . ARG E 1 354 ? 214.107 305.541 234.398 1.00 59.65  ? 354 ARG E CB  1 
ATOM   14043 C  CG  . ARG E 1 354 ? 214.836 305.732 233.077 1.00 64.98  ? 354 ARG E CG  1 
ATOM   14044 C  CD  . ARG E 1 354 ? 214.730 304.500 232.194 1.00 73.65  ? 354 ARG E CD  1 
ATOM   14045 N  NE  . ARG E 1 354 ? 215.980 303.750 232.156 1.00 79.43  ? 354 ARG E NE  1 
ATOM   14046 C  CZ  . ARG E 1 354 ? 216.173 302.582 232.754 1.00 76.95  ? 354 ARG E CZ  1 
ATOM   14047 N  NH1 . ARG E 1 354 ? 215.217 302.001 233.460 1.00 77.38  ? 354 ARG E NH1 1 
ATOM   14048 N  NH2 . ARG E 1 354 ? 217.355 301.983 232.642 1.00 68.55  ? 354 ARG E NH2 1 
ATOM   14049 N  N   . GLY E 1 355 ? 214.230 305.855 237.914 1.00 52.75  ? 355 GLY E N   1 
ATOM   14050 C  CA  . GLY E 1 355 ? 213.414 305.867 239.108 1.00 43.52  ? 355 GLY E CA  1 
ATOM   14051 C  C   . GLY E 1 355 ? 212.562 304.640 239.332 1.00 48.98  ? 355 GLY E C   1 
ATOM   14052 O  O   . GLY E 1 355 ? 211.650 304.686 240.166 1.00 47.37  ? 355 GLY E O   1 
ATOM   14053 N  N   . CYS E 1 356 ? 212.823 303.546 238.622 1.00 50.97  ? 356 CYS E N   1 
ATOM   14054 C  CA  . CYS E 1 356 ? 212.074 302.310 238.801 1.00 39.61  ? 356 CYS E CA  1 
ATOM   14055 C  C   . CYS E 1 356 ? 212.745 301.460 239.871 1.00 33.98  ? 356 CYS E C   1 
ATOM   14056 O  O   . CYS E 1 356 ? 213.964 301.266 239.843 1.00 35.85  ? 356 CYS E O   1 
ATOM   14057 C  CB  . CYS E 1 356 ? 211.987 301.536 237.485 1.00 43.29  ? 356 CYS E CB  1 
ATOM   14058 S  SG  . CYS E 1 356 ? 211.617 302.551 236.037 1.00 66.91  ? 356 CYS E SG  1 
ATOM   14059 N  N   . PHE E 1 357 ? 211.951 300.959 240.812 1.00 31.16  ? 357 PHE E N   1 
ATOM   14060 C  CA  . PHE E 1 357 ? 212.495 300.152 241.894 1.00 25.62  ? 357 PHE E CA  1 
ATOM   14061 C  C   . PHE E 1 357 ? 212.944 298.789 241.380 1.00 24.81  ? 357 PHE E C   1 
ATOM   14062 O  O   . PHE E 1 357 ? 212.386 298.241 240.427 1.00 25.89  ? 357 PHE E O   1 
ATOM   14063 C  CB  . PHE E 1 357 ? 211.461 299.992 243.008 1.00 22.02  ? 357 PHE E CB  1 
ATOM   14064 C  CG  . PHE E 1 357 ? 211.239 301.243 243.807 1.00 24.75  ? 357 PHE E CG  1 
ATOM   14065 C  CD1 . PHE E 1 357 ? 212.091 301.577 244.846 1.00 19.99  ? 357 PHE E CD1 1 
ATOM   14066 C  CD2 . PHE E 1 357 ? 210.190 302.094 243.510 1.00 23.01  ? 357 PHE E CD2 1 
ATOM   14067 C  CE1 . PHE E 1 357 ? 211.895 302.727 245.575 1.00 19.14  ? 357 PHE E CE1 1 
ATOM   14068 C  CE2 . PHE E 1 357 ? 209.990 303.246 244.240 1.00 22.98  ? 357 PHE E CE2 1 
ATOM   14069 C  CZ  . PHE E 1 357 ? 210.843 303.563 245.273 1.00 19.08  ? 357 PHE E CZ  1 
ATOM   14070 N  N   . LEU E 1 358 ? 213.969 298.243 242.028 1.00 23.74  ? 358 LEU E N   1 
ATOM   14071 C  CA  . LEU E 1 358 ? 214.597 297.002 241.597 1.00 19.64  ? 358 LEU E CA  1 
ATOM   14072 C  C   . LEU E 1 358 ? 213.998 295.765 242.255 1.00 23.49  ? 358 LEU E C   1 
ATOM   14073 O  O   . LEU E 1 358 ? 214.452 294.653 241.972 1.00 33.34  ? 358 LEU E O   1 
ATOM   14074 C  CB  . LEU E 1 358 ? 216.104 297.062 241.870 1.00 21.79  ? 358 LEU E CB  1 
ATOM   14075 C  CG  . LEU E 1 358 ? 216.851 298.190 241.152 1.00 27.81  ? 358 LEU E CG  1 
ATOM   14076 C  CD1 . LEU E 1 358 ? 218.242 298.386 241.727 1.00 28.44  ? 358 LEU E CD1 1 
ATOM   14077 C  CD2 . LEU E 1 358 ? 216.921 297.919 239.659 1.00 22.61  ? 358 LEU E CD2 1 
ATOM   14078 N  N   . GLY E 1 359 ? 212.996 295.926 243.115 1.00 19.51  ? 359 GLY E N   1 
ATOM   14079 C  CA  . GLY E 1 359 ? 212.362 294.795 243.763 1.00 14.36  ? 359 GLY E CA  1 
ATOM   14080 C  C   . GLY E 1 359 ? 211.015 295.197 244.322 1.00 16.68  ? 359 GLY E C   1 
ATOM   14081 O  O   . GLY E 1 359 ? 210.616 296.362 244.264 1.00 22.12  ? 359 GLY E O   1 
ATOM   14082 N  N   . ASN E 1 360 ? 210.311 294.209 244.871 1.00 15.44  ? 360 ASN E N   1 
ATOM   14083 C  CA  . ASN E 1 360 ? 208.971 294.397 245.421 1.00 13.21  ? 360 ASN E CA  1 
ATOM   14084 C  C   . ASN E 1 360 ? 209.055 294.320 246.940 1.00 13.98  ? 360 ASN E C   1 
ATOM   14085 O  O   . ASN E 1 360 ? 209.212 293.234 247.506 1.00 14.57  ? 360 ASN E O   1 
ATOM   14086 C  CB  . ASN E 1 360 ? 208.003 293.353 244.869 1.00 13.39  ? 360 ASN E CB  1 
ATOM   14087 C  CG  . ASN E 1 360 ? 206.638 293.417 245.523 1.00 17.42  ? 360 ASN E CG  1 
ATOM   14088 O  OD1 . ASN E 1 360 ? 206.224 294.463 246.021 1.00 24.46  ? 360 ASN E OD1 1 
ATOM   14089 N  ND2 . ASN E 1 360 ? 205.926 292.298 245.518 1.00 18.29  ? 360 ASN E ND2 1 
ATOM   14090 N  N   . PHE E 1 361 ? 208.951 295.470 247.593 1.00 14.83  ? 361 PHE E N   1 
ATOM   14091 C  CA  . PHE E 1 361 ? 209.014 295.555 249.046 1.00 13.03  ? 361 PHE E CA  1 
ATOM   14092 C  C   . PHE E 1 361 ? 208.161 296.743 249.476 1.00 12.66  ? 361 PHE E C   1 
ATOM   14093 O  O   . PHE E 1 361 ? 207.339 297.244 248.703 1.00 19.78  ? 361 PHE E O   1 
ATOM   14094 C  CB  . PHE E 1 361 ? 210.475 295.661 249.518 1.00 14.17  ? 361 PHE E CB  1 
ATOM   14095 C  CG  . PHE E 1 361 ? 211.151 296.943 249.121 1.00 15.22  ? 361 PHE E CG  1 
ATOM   14096 C  CD1 . PHE E 1 361 ? 211.429 297.212 247.793 1.00 13.97  ? 361 PHE E CD1 1 
ATOM   14097 C  CD2 . PHE E 1 361 ? 211.519 297.873 250.078 1.00 13.60  ? 361 PHE E CD2 1 
ATOM   14098 C  CE1 . PHE E 1 361 ? 212.050 298.387 247.427 1.00 16.30  ? 361 PHE E CE1 1 
ATOM   14099 C  CE2 . PHE E 1 361 ? 212.141 299.048 249.718 1.00 13.01  ? 361 PHE E CE2 1 
ATOM   14100 C  CZ  . PHE E 1 361 ? 212.407 299.306 248.390 1.00 15.03  ? 361 PHE E CZ  1 
ATOM   14101 N  N   . LYS E 1 362 ? 208.352 297.194 250.708 1.00 14.17  ? 362 LYS E N   1 
ATOM   14102 C  CA  . LYS E 1 362 ? 207.661 298.374 251.206 1.00 15.68  ? 362 LYS E CA  1 
ATOM   14103 C  C   . LYS E 1 362 ? 208.609 299.567 251.149 1.00 16.80  ? 362 LYS E C   1 
ATOM   14104 O  O   . LYS E 1 362 ? 209.340 299.823 252.113 1.00 20.70  ? 362 LYS E O   1 
ATOM   14105 C  CB  . LYS E 1 362 ? 207.162 298.137 252.632 1.00 13.09  ? 362 LYS E CB  1 
ATOM   14106 C  CG  . LYS E 1 362 ? 206.034 299.044 253.061 1.00 15.82  ? 362 LYS E CG  1 
ATOM   14107 C  CD  . LYS E 1 362 ? 205.924 299.087 254.567 1.00 17.87  ? 362 LYS E CD  1 
ATOM   14108 C  CE  . LYS E 1 362 ? 204.680 299.827 255.001 1.00 19.20  ? 362 LYS E CE  1 
ATOM   14109 N  NZ  . LYS E 1 362 ? 204.366 299.565 256.428 1.00 19.84  ? 362 LYS E NZ  1 
ATOM   14110 N  N   . PRO E 1 363 ? 208.629 300.315 250.041 1.00 19.18  ? 363 PRO E N   1 
ATOM   14111 C  CA  . PRO E 1 363 ? 209.615 301.395 249.895 1.00 18.89  ? 363 PRO E CA  1 
ATOM   14112 C  C   . PRO E 1 363 ? 209.276 302.633 250.708 1.00 14.68  ? 363 PRO E C   1 
ATOM   14113 O  O   . PRO E 1 363 ? 210.175 303.340 251.173 1.00 19.06  ? 363 PRO E O   1 
ATOM   14114 C  CB  . PRO E 1 363 ? 209.589 301.695 248.388 1.00 13.62  ? 363 PRO E CB  1 
ATOM   14115 C  CG  . PRO E 1 363 ? 208.806 300.583 247.763 1.00 12.85  ? 363 PRO E CG  1 
ATOM   14116 C  CD  . PRO E 1 363 ? 207.862 300.107 248.805 1.00 15.86  ? 363 PRO E CD  1 
ATOM   14117 N  N   . GLY E 1 364 ? 207.985 302.916 250.877 1.00 18.06  ? 364 GLY E N   1 
ATOM   14118 C  CA  . GLY E 1 364 ? 207.531 304.074 251.607 1.00 19.15  ? 364 GLY E CA  1 
ATOM   14119 C  C   . GLY E 1 364 ? 206.816 303.705 252.896 1.00 20.65  ? 364 GLY E C   1 
ATOM   14120 O  O   . GLY E 1 364 ? 206.621 302.541 253.232 1.00 26.26  ? 364 GLY E O   1 
ATOM   14121 N  N   . GLU E 1 365 ? 206.420 304.746 253.621 1.00 25.12  ? 365 GLU E N   1 
ATOM   14122 C  CA  . GLU E 1 365 ? 205.690 304.572 254.869 1.00 27.01  ? 365 GLU E CA  1 
ATOM   14123 C  C   . GLU E 1 365 ? 204.216 304.339 254.562 1.00 26.09  ? 365 GLU E C   1 
ATOM   14124 O  O   . GLU E 1 365 ? 203.546 305.215 254.006 1.00 31.32  ? 365 GLU E O   1 
ATOM   14125 C  CB  . GLU E 1 365 ? 205.869 305.793 255.766 1.00 24.79  ? 365 GLU E CB  1 
ATOM   14126 C  CG  . GLU E 1 365 ? 205.105 305.715 257.074 1.00 29.81  ? 365 GLU E CG  1 
ATOM   14127 C  CD  . GLU E 1 365 ? 204.971 307.063 257.746 1.00 49.13  ? 365 GLU E CD  1 
ATOM   14128 O  OE1 . GLU E 1 365 ? 204.956 308.085 257.028 1.00 59.83  ? 365 GLU E OE1 1 
ATOM   14129 O  OE2 . GLU E 1 365 ? 204.877 307.103 258.990 1.00 54.95  ? 365 GLU E OE2 1 
ATOM   14130 N  N   . GLY E 1 366 ? 203.713 303.162 254.924 1.00 28.58  ? 366 GLY E N   1 
ATOM   14131 C  CA  . GLY E 1 366 ? 202.350 302.795 254.598 1.00 18.08  ? 366 GLY E CA  1 
ATOM   14132 C  C   . GLY E 1 366 ? 202.133 302.725 253.102 1.00 21.68  ? 366 GLY E C   1 
ATOM   14133 O  O   . GLY E 1 366 ? 200.994 302.743 252.629 1.00 32.89  ? 366 GLY E O   1 
ATOM   14134 N  N   . ASP E 1 367 ? 203.230 302.642 252.349 1.00 27.72  ? 367 ASP E N   1 
ATOM   14135 C  CA  . ASP E 1 367 ? 203.219 302.713 250.887 1.00 23.26  ? 367 ASP E CA  1 
ATOM   14136 C  C   . ASP E 1 367 ? 203.942 301.480 250.351 1.00 22.49  ? 367 ASP E C   1 
ATOM   14137 O  O   . ASP E 1 367 ? 205.153 301.511 250.122 1.00 25.02  ? 367 ASP E O   1 
ATOM   14138 C  CB  . ASP E 1 367 ? 203.872 304.009 250.405 1.00 22.92  ? 367 ASP E CB  1 
ATOM   14139 C  CG  . ASP E 1 367 ? 203.811 304.178 248.898 1.00 32.62  ? 367 ASP E CG  1 
ATOM   14140 O  OD1 . ASP E 1 367 ? 203.624 303.174 248.182 1.00 37.64  ? 367 ASP E OD1 1 
ATOM   14141 O  OD2 . ASP E 1 367 ? 203.956 305.325 248.427 1.00 37.99  ? 367 ASP E OD2 1 
ATOM   14142 N  N   . TYR E 1 368 ? 203.193 300.394 250.158 1.00 23.24  ? 368 TYR E N   1 
ATOM   14143 C  CA  . TYR E 1 368 ? 203.749 299.181 249.574 1.00 16.46  ? 368 TYR E CA  1 
ATOM   14144 C  C   . TYR E 1 368 ? 203.804 299.231 248.055 1.00 24.77  ? 368 TYR E C   1 
ATOM   14145 O  O   . TYR E 1 368 ? 204.558 298.462 247.449 1.00 28.16  ? 368 TYR E O   1 
ATOM   14146 C  CB  . TYR E 1 368 ? 202.925 297.960 249.992 1.00 15.68  ? 368 TYR E CB  1 
ATOM   14147 C  CG  . TYR E 1 368 ? 202.713 297.801 251.478 1.00 17.60  ? 368 TYR E CG  1 
ATOM   14148 C  CD1 . TYR E 1 368 ? 201.799 298.594 252.159 1.00 15.22  ? 368 TYR E CD1 1 
ATOM   14149 C  CD2 . TYR E 1 368 ? 203.411 296.843 252.199 1.00 15.94  ? 368 TYR E CD2 1 
ATOM   14150 C  CE1 . TYR E 1 368 ? 201.598 298.449 253.512 1.00 14.24  ? 368 TYR E CE1 1 
ATOM   14151 C  CE2 . TYR E 1 368 ? 203.216 296.689 253.557 1.00 16.10  ? 368 TYR E CE2 1 
ATOM   14152 C  CZ  . TYR E 1 368 ? 202.308 297.494 254.207 1.00 19.07  ? 368 TYR E CZ  1 
ATOM   14153 O  OH  . TYR E 1 368 ? 202.107 297.346 255.557 1.00 31.20  ? 368 TYR E OH  1 
ATOM   14154 N  N   . THR E 1 369 ? 203.028 300.112 247.430 1.00 25.50  ? 369 THR E N   1 
ATOM   14155 C  CA  . THR E 1 369 ? 202.807 300.098 245.992 1.00 19.46  ? 369 THR E CA  1 
ATOM   14156 C  C   . THR E 1 369 ? 203.761 301.003 245.223 1.00 22.30  ? 369 THR E C   1 
ATOM   14157 O  O   . THR E 1 369 ? 203.594 301.166 244.012 1.00 25.44  ? 369 THR E O   1 
ATOM   14158 C  CB  . THR E 1 369 ? 201.361 300.495 245.684 1.00 21.34  ? 369 THR E CB  1 
ATOM   14159 O  OG1 . THR E 1 369 ? 200.966 301.571 246.543 1.00 30.83  ? 369 THR E OG1 1 
ATOM   14160 C  CG2 . THR E 1 369 ? 200.430 299.322 245.909 1.00 15.91  ? 369 THR E CG2 1 
ATOM   14161 N  N   . ALA E 1 370 ? 204.750 301.601 245.891 1.00 24.17  ? 370 ALA E N   1 
ATOM   14162 C  CA  . ALA E 1 370 ? 205.681 302.474 245.184 1.00 20.66  ? 370 ALA E CA  1 
ATOM   14163 C  C   . ALA E 1 370 ? 206.418 301.729 244.079 1.00 22.88  ? 370 ALA E C   1 
ATOM   14164 O  O   . ALA E 1 370 ? 206.829 302.341 243.086 1.00 25.86  ? 370 ALA E O   1 
ATOM   14165 C  CB  . ALA E 1 370 ? 206.676 303.090 246.167 1.00 19.64  ? 370 ALA E CB  1 
ATOM   14166 N  N   . ASP E 1 371 ? 206.593 300.418 244.227 1.00 23.30  ? 371 ASP E N   1 
ATOM   14167 C  CA  . ASP E 1 371 ? 207.208 299.587 243.203 1.00 19.75  ? 371 ASP E CA  1 
ATOM   14168 C  C   . ASP E 1 371 ? 206.193 298.990 242.238 1.00 23.40  ? 371 ASP E C   1 
ATOM   14169 O  O   . ASP E 1 371 ? 206.583 298.249 241.332 1.00 28.29  ? 371 ASP E O   1 
ATOM   14170 C  CB  . ASP E 1 371 ? 208.021 298.463 243.853 1.00 16.13  ? 371 ASP E CB  1 
ATOM   14171 C  CG  . ASP E 1 371 ? 207.296 297.811 245.011 1.00 20.19  ? 371 ASP E CG  1 
ATOM   14172 O  OD1 . ASP E 1 371 ? 206.084 297.541 244.891 1.00 23.69  ? 371 ASP E OD1 1 
ATOM   14173 O  OD2 . ASP E 1 371 ? 207.941 297.561 246.046 1.00 26.84  ? 371 ASP E OD2 1 
ATOM   14174 N  N   . GLY E 1 372 ? 204.909 299.295 242.408 1.00 20.72  ? 372 GLY E N   1 
ATOM   14175 C  CA  . GLY E 1 372 ? 203.865 298.806 241.542 1.00 14.71  ? 372 GLY E CA  1 
ATOM   14176 C  C   . GLY E 1 372 ? 203.040 297.674 242.116 1.00 18.21  ? 372 GLY E C   1 
ATOM   14177 O  O   . GLY E 1 372 ? 201.945 297.409 241.609 1.00 23.34  ? 372 GLY E O   1 
ATOM   14178 N  N   . HIS E 1 373 ? 203.527 297.005 243.155 1.00 19.05  ? 373 HIS E N   1 
ATOM   14179 C  CA  . HIS E 1 373 ? 202.858 295.836 243.705 1.00 16.46  ? 373 HIS E CA  1 
ATOM   14180 C  C   . HIS E 1 373 ? 202.660 296.003 245.202 1.00 17.19  ? 373 HIS E C   1 
ATOM   14181 O  O   . HIS E 1 373 ? 203.558 296.464 245.911 1.00 26.14  ? 373 HIS E O   1 
ATOM   14182 C  CB  . HIS E 1 373 ? 203.658 294.563 243.417 1.00 16.28  ? 373 HIS E CB  1 
ATOM   14183 C  CG  . HIS E 1 373 ? 204.046 294.413 241.980 1.00 17.42  ? 373 HIS E CG  1 
ATOM   14184 N  ND1 . HIS E 1 373 ? 203.188 293.910 241.027 1.00 19.23  ? 373 HIS E ND1 1 
ATOM   14185 C  CD2 . HIS E 1 373 ? 205.191 294.722 241.330 1.00 18.22  ? 373 HIS E CD2 1 
ATOM   14186 C  CE1 . HIS E 1 373 ? 203.793 293.906 239.852 1.00 16.87  ? 373 HIS E CE1 1 
ATOM   14187 N  NE2 . HIS E 1 373 ? 205.009 294.395 240.009 1.00 21.78  ? 373 HIS E NE2 1 
ATOM   14188 N  N   . LEU E 1 374 ? 201.477 295.618 245.672 1.00 16.13  ? 374 LEU E N   1 
ATOM   14189 C  CA  . LEU E 1 374 ? 201.137 295.652 247.088 1.00 15.96  ? 374 LEU E CA  1 
ATOM   14190 C  C   . LEU E 1 374 ? 201.452 294.327 247.772 1.00 19.95  ? 374 LEU E C   1 
ATOM   14191 O  O   . LEU E 1 374 ? 202.100 294.302 248.821 1.00 22.42  ? 374 LEU E O   1 
ATOM   14192 C  CB  . LEU E 1 374 ? 199.657 296.007 247.252 1.00 20.02  ? 374 LEU E CB  1 
ATOM   14193 C  CG  . LEU E 1 374 ? 199.004 295.748 248.608 1.00 20.83  ? 374 LEU E CG  1 
ATOM   14194 C  CD1 . LEU E 1 374 ? 199.777 296.432 249.713 1.00 17.86  ? 374 LEU E CD1 1 
ATOM   14195 C  CD2 . LEU E 1 374 ? 197.567 296.232 248.586 1.00 18.35  ? 374 LEU E CD2 1 
ATOM   14196 N  N   . ILE E 1 375 ? 201.002 293.225 247.183 1.00 21.94  ? 375 ILE E N   1 
ATOM   14197 C  CA  . ILE E 1 375 ? 201.269 291.877 247.678 1.00 16.54  ? 375 ILE E CA  1 
ATOM   14198 C  C   . ILE E 1 375 ? 202.288 291.246 246.737 1.00 17.24  ? 375 ILE E C   1 
ATOM   14199 O  O   . ILE E 1 375 ? 202.710 291.899 245.772 1.00 21.30  ? 375 ILE E O   1 
ATOM   14200 C  CB  . ILE E 1 375 ? 199.978 291.049 247.777 1.00 18.68  ? 375 ILE E CB  1 
ATOM   14201 C  CG1 . ILE E 1 375 ? 199.225 291.063 246.445 1.00 18.17  ? 375 ILE E CG1 1 
ATOM   14202 C  CG2 . ILE E 1 375 ? 199.100 291.563 248.907 1.00 12.65  ? 375 ILE E CG2 1 
ATOM   14203 C  CD1 . ILE E 1 375 ? 198.732 289.706 246.016 1.00 12.75  ? 375 ILE E CD1 1 
ATOM   14204 N  N   . PRO E 1 376 ? 202.740 290.016 246.981 1.00 18.53  ? 376 PRO E N   1 
ATOM   14205 C  CA  . PRO E 1 376 ? 203.761 289.428 246.107 1.00 16.24  ? 376 PRO E CA  1 
ATOM   14206 C  C   . PRO E 1 376 ? 203.333 289.486 244.647 1.00 17.83  ? 376 PRO E C   1 
ATOM   14207 O  O   . PRO E 1 376 ? 202.178 289.229 244.307 1.00 24.46  ? 376 PRO E O   1 
ATOM   14208 C  CB  . PRO E 1 376 ? 203.866 287.983 246.605 1.00 12.97  ? 376 PRO E CB  1 
ATOM   14209 C  CG  . PRO E 1 376 ? 203.329 288.007 247.983 1.00 14.29  ? 376 PRO E CG  1 
ATOM   14210 C  CD  . PRO E 1 376 ? 202.291 289.077 248.022 1.00 14.86  ? 376 PRO E CD  1 
ATOM   14211 N  N   . SER E 1 377 ? 204.280 289.834 243.783 1.00 16.86  ? 377 SER E N   1 
ATOM   14212 C  CA  . SER E 1 377 ? 204.019 289.950 242.359 1.00 16.23  ? 377 SER E CA  1 
ATOM   14213 C  C   . SER E 1 377 ? 204.387 288.657 241.637 1.00 19.19  ? 377 SER E C   1 
ATOM   14214 O  O   . SER E 1 377 ? 204.969 287.734 242.208 1.00 22.33  ? 377 SER E O   1 
ATOM   14215 C  CB  . SER E 1 377 ? 204.794 291.128 241.767 1.00 16.21  ? 377 SER E CB  1 
ATOM   14216 O  OG  . SER E 1 377 ? 206.188 290.981 241.968 1.00 19.89  ? 377 SER E OG  1 
ATOM   14217 N  N   . ARG E 1 378 ? 204.027 288.599 240.359 1.00 21.13  ? 378 ARG E N   1 
ATOM   14218 C  CA  . ARG E 1 378 ? 204.409 287.470 239.524 1.00 16.29  ? 378 ARG E CA  1 
ATOM   14219 C  C   . ARG E 1 378 ? 205.927 287.350 239.470 1.00 24.06  ? 378 ARG E C   1 
ATOM   14220 O  O   . ARG E 1 378 ? 206.642 288.350 239.365 1.00 30.99  ? 378 ARG E O   1 
ATOM   14221 C  CB  . ARG E 1 378 ? 203.835 287.649 238.120 1.00 20.41  ? 378 ARG E CB  1 
ATOM   14222 C  CG  . ARG E 1 378 ? 203.929 286.431 237.228 1.00 28.64  ? 378 ARG E CG  1 
ATOM   14223 C  CD  . ARG E 1 378 ? 203.656 286.819 235.788 1.00 33.43  ? 378 ARG E CD  1 
ATOM   14224 N  NE  . ARG E 1 378 ? 202.812 288.005 235.715 1.00 40.37  ? 378 ARG E NE  1 
ATOM   14225 C  CZ  . ARG E 1 378 ? 201.487 287.981 235.693 1.00 46.45  ? 378 ARG E CZ  1 
ATOM   14226 N  NH1 . ARG E 1 378 ? 200.816 286.841 235.712 1.00 41.19  ? 378 ARG E NH1 1 
ATOM   14227 N  NH2 . ARG E 1 378 ? 200.817 289.130 235.658 1.00 43.80  ? 378 ARG E NH2 1 
ATOM   14228 N  N   . VAL E 1 379 ? 206.422 286.114 239.542 1.00 21.94  ? 379 VAL E N   1 
ATOM   14229 C  CA  . VAL E 1 379 ? 207.862 285.892 239.577 1.00 21.64  ? 379 VAL E CA  1 
ATOM   14230 C  C   . VAL E 1 379 ? 208.487 286.366 238.273 1.00 22.40  ? 379 VAL E C   1 
ATOM   14231 O  O   . VAL E 1 379 ? 207.885 286.261 237.196 1.00 24.11  ? 379 VAL E O   1 
ATOM   14232 C  CB  . VAL E 1 379 ? 208.179 284.409 239.840 1.00 20.80  ? 379 VAL E CB  1 
ATOM   14233 C  CG1 . VAL E 1 379 ? 207.592 283.967 241.171 1.00 17.31  ? 379 VAL E CG1 1 
ATOM   14234 C  CG2 . VAL E 1 379 ? 207.666 283.541 238.703 1.00 17.55  ? 379 VAL E CG2 1 
ATOM   14235 N  N   . SER E 1 380 ? 209.707 286.898 238.369 1.00 22.40  ? 380 SER E N   1 
ATOM   14236 C  CA  . SER E 1 380 ? 210.443 287.429 237.224 1.00 21.94  ? 380 SER E CA  1 
ATOM   14237 C  C   . SER E 1 380 ? 209.867 288.753 236.732 1.00 23.52  ? 380 SER E C   1 
ATOM   14238 O  O   . SER E 1 380 ? 209.951 289.068 235.543 1.00 29.85  ? 380 SER E O   1 
ATOM   14239 C  CB  . SER E 1 380 ? 210.495 286.419 236.074 1.00 20.73  ? 380 SER E CB  1 
ATOM   14240 O  OG  . SER E 1 380 ? 211.033 285.182 236.502 1.00 31.14  ? 380 SER E OG  1 
ATOM   14241 N  N   . SER E 1 381 ? 209.277 289.539 237.633 1.00 22.00  ? 381 SER E N   1 
ATOM   14242 C  CA  . SER E 1 381 ? 208.739 290.842 237.263 1.00 22.73  ? 381 SER E CA  1 
ATOM   14243 C  C   . SER E 1 381 ? 209.793 291.939 237.253 1.00 19.10  ? 381 SER E C   1 
ATOM   14244 O  O   . SER E 1 381 ? 209.518 293.035 236.755 1.00 23.45  ? 381 SER E O   1 
ATOM   14245 C  CB  . SER E 1 381 ? 207.604 291.232 238.213 1.00 21.17  ? 381 SER E CB  1 
ATOM   14246 O  OG  . SER E 1 381 ? 206.385 290.629 237.820 1.00 23.85  ? 381 SER E OG  1 
ATOM   14247 N  N   . PHE E 1 382 ? 210.979 291.677 237.785 1.00 20.42  ? 382 PHE E N   1 
ATOM   14248 C  CA  . PHE E 1 382 ? 212.085 292.621 237.783 1.00 19.58  ? 382 PHE E CA  1 
ATOM   14249 C  C   . PHE E 1 382 ? 213.289 291.975 237.099 1.00 22.11  ? 382 PHE E C   1 
ATOM   14250 O  O   . PHE E 1 382 ? 213.201 290.875 236.548 1.00 27.06  ? 382 PHE E O   1 
ATOM   14251 C  CB  . PHE E 1 382 ? 212.406 293.077 239.208 1.00 20.23  ? 382 PHE E CB  1 
ATOM   14252 C  CG  . PHE E 1 382 ? 211.232 293.669 239.936 1.00 21.37  ? 382 PHE E CG  1 
ATOM   14253 C  CD1 . PHE E 1 382 ? 210.289 292.854 240.538 1.00 16.79  ? 382 PHE E CD1 1 
ATOM   14254 C  CD2 . PHE E 1 382 ? 211.073 295.040 240.020 1.00 20.16  ? 382 PHE E CD2 1 
ATOM   14255 C  CE1 . PHE E 1 382 ? 209.212 293.395 241.202 1.00 16.94  ? 382 PHE E CE1 1 
ATOM   14256 C  CE2 . PHE E 1 382 ? 209.999 295.586 240.688 1.00 15.72  ? 382 PHE E CE2 1 
ATOM   14257 C  CZ  . PHE E 1 382 ? 209.067 294.762 241.278 1.00 17.71  ? 382 PHE E CZ  1 
ATOM   14258 N  N   . SER E 1 383 ? 214.415 292.670 237.132 1.00 22.93  ? 383 SER E N   1 
ATOM   14259 C  CA  . SER E 1 383 ? 215.610 292.162 236.482 1.00 23.26  ? 383 SER E CA  1 
ATOM   14260 C  C   . SER E 1 383 ? 216.257 291.058 237.318 1.00 24.94  ? 383 SER E C   1 
ATOM   14261 O  O   . SER E 1 383 ? 216.126 291.039 238.544 1.00 27.86  ? 383 SER E O   1 
ATOM   14262 C  CB  . SER E 1 383 ? 216.610 293.289 236.257 1.00 23.57  ? 383 SER E CB  1 
ATOM   14263 O  OG  . SER E 1 383 ? 216.402 293.903 234.999 1.00 35.40  ? 383 SER E OG  1 
ATOM   14264 N  N   . PRO E 1 384 ? 216.964 290.129 236.676 1.00 26.94  ? 384 PRO E N   1 
ATOM   14265 C  CA  . PRO E 1 384 ? 217.604 289.044 237.428 1.00 20.65  ? 384 PRO E CA  1 
ATOM   14266 C  C   . PRO E 1 384 ? 218.993 289.409 237.926 1.00 22.65  ? 384 PRO E C   1 
ATOM   14267 O  O   . PRO E 1 384 ? 219.470 290.528 237.716 1.00 25.71  ? 384 PRO E O   1 
ATOM   14268 C  CB  . PRO E 1 384 ? 217.661 287.906 236.405 1.00 19.77  ? 384 PRO E CB  1 
ATOM   14269 C  CG  . PRO E 1 384 ? 217.798 288.607 235.098 1.00 22.17  ? 384 PRO E CG  1 
ATOM   14270 C  CD  . PRO E 1 384 ? 217.080 289.933 235.220 1.00 24.97  ? 384 PRO E CD  1 
ATOM   14271 N  N   . ASN E 1 385 ? 219.642 288.460 238.593 1.00 25.49  ? 385 ASN E N   1 
ATOM   14272 C  CA  . ASN E 1 385 ? 221.007 288.614 239.064 1.00 23.05  ? 385 ASN E CA  1 
ATOM   14273 C  C   . ASN E 1 385 ? 221.996 288.495 237.908 1.00 31.85  ? 385 ASN E C   1 
ATOM   14274 O  O   . ASN E 1 385 ? 221.635 288.200 236.765 1.00 31.98  ? 385 ASN E O   1 
ATOM   14275 C  CB  . ASN E 1 385 ? 221.327 287.557 240.117 1.00 21.37  ? 385 ASN E CB  1 
ATOM   14276 C  CG  . ASN E 1 385 ? 221.316 288.106 241.512 1.00 25.46  ? 385 ASN E CG  1 
ATOM   14277 O  OD1 . ASN E 1 385 ? 221.329 289.319 241.712 1.00 36.31  ? 385 ASN E OD1 1 
ATOM   14278 N  ND2 . ASN E 1 385 ? 221.310 287.215 242.495 1.00 24.64  ? 385 ASN E ND2 1 
ATOM   14279 N  N   . ASP E 1 386 ? 223.272 288.728 238.217 1.00 29.99  ? 386 ASP E N   1 
ATOM   14280 C  CA  . ASP E 1 386 ? 224.331 288.303 237.312 1.00 29.52  ? 386 ASP E CA  1 
ATOM   14281 C  C   . ASP E 1 386 ? 224.387 286.785 237.222 1.00 29.93  ? 386 ASP E C   1 
ATOM   14282 O  O   . ASP E 1 386 ? 224.830 286.237 236.207 1.00 31.87  ? 386 ASP E O   1 
ATOM   14283 C  CB  . ASP E 1 386 ? 225.673 288.866 237.773 1.00 34.54  ? 386 ASP E CB  1 
ATOM   14284 C  CG  . ASP E 1 386 ? 225.857 290.318 237.384 1.00 41.60  ? 386 ASP E CG  1 
ATOM   14285 O  OD1 . ASP E 1 386 ? 224.985 290.860 236.674 1.00 46.87  ? 386 ASP E OD1 1 
ATOM   14286 O  OD2 . ASP E 1 386 ? 226.870 290.920 237.796 1.00 51.57  ? 386 ASP E OD2 1 
ATOM   14287 N  N   . PHE E 1 387 ? 223.940 286.095 238.272 1.00 25.91  ? 387 PHE E N   1 
ATOM   14288 C  CA  . PHE E 1 387 ? 223.773 284.650 238.246 1.00 21.09  ? 387 PHE E CA  1 
ATOM   14289 C  C   . PHE E 1 387 ? 222.501 284.219 237.530 1.00 22.76  ? 387 PHE E C   1 
ATOM   14290 O  O   . PHE E 1 387 ? 222.345 283.027 237.247 1.00 29.13  ? 387 PHE E O   1 
ATOM   14291 C  CB  . PHE E 1 387 ? 223.765 284.095 239.674 1.00 21.36  ? 387 PHE E CB  1 
ATOM   14292 C  CG  . PHE E 1 387 ? 225.112 284.102 240.338 1.00 20.94  ? 387 PHE E CG  1 
ATOM   14293 C  CD1 . PHE E 1 387 ? 226.269 284.183 239.587 1.00 19.32  ? 387 PHE E CD1 1 
ATOM   14294 C  CD2 . PHE E 1 387 ? 225.219 284.020 241.716 1.00 19.98  ? 387 PHE E CD2 1 
ATOM   14295 C  CE1 . PHE E 1 387 ? 227.506 284.186 240.195 1.00 19.83  ? 387 PHE E CE1 1 
ATOM   14296 C  CE2 . PHE E 1 387 ? 226.454 284.023 242.329 1.00 19.93  ? 387 PHE E CE2 1 
ATOM   14297 C  CZ  . PHE E 1 387 ? 227.598 284.108 241.568 1.00 18.82  ? 387 PHE E CZ  1 
ATOM   14298 N  N   . GLY E 1 388 ? 221.600 285.150 237.228 1.00 22.20  ? 388 GLY E N   1 
ATOM   14299 C  CA  . GLY E 1 388 ? 220.342 284.816 236.594 1.00 18.31  ? 388 GLY E CA  1 
ATOM   14300 C  C   . GLY E 1 388 ? 219.202 284.502 237.534 1.00 19.86  ? 388 GLY E C   1 
ATOM   14301 O  O   . GLY E 1 388 ? 218.227 283.874 237.108 1.00 19.60  ? 388 GLY E O   1 
ATOM   14302 N  N   . LEU E 1 389 ? 219.286 284.915 238.795 1.00 21.62  ? 389 LEU E N   1 
ATOM   14303 C  CA  . LEU E 1 389 ? 218.263 284.625 239.789 1.00 15.88  ? 389 LEU E CA  1 
ATOM   14304 C  C   . LEU E 1 389 ? 217.302 285.799 239.933 1.00 16.92  ? 389 LEU E C   1 
ATOM   14305 O  O   . LEU E 1 389 ? 217.692 286.964 239.825 1.00 18.19  ? 389 LEU E O   1 
ATOM   14306 C  CB  . LEU E 1 389 ? 218.898 284.301 241.141 1.00 15.67  ? 389 LEU E CB  1 
ATOM   14307 C  CG  . LEU E 1 389 ? 219.811 283.074 241.156 1.00 14.81  ? 389 LEU E CG  1 
ATOM   14308 C  CD1 . LEU E 1 389 ? 220.798 283.140 242.304 1.00 11.72  ? 389 LEU E CD1 1 
ATOM   14309 C  CD2 . LEU E 1 389 ? 218.983 281.803 241.228 1.00 15.47  ? 389 LEU E CD2 1 
ATOM   14310 N  N   . TYR E 1 390 ? 216.039 285.479 240.192 1.00 19.17  ? 390 TYR E N   1 
ATOM   14311 C  CA  . TYR E 1 390 ? 214.974 286.466 240.278 1.00 14.42  ? 390 TYR E CA  1 
ATOM   14312 C  C   . TYR E 1 390 ? 214.450 286.575 241.703 1.00 14.89  ? 390 TYR E C   1 
ATOM   14313 O  O   . TYR E 1 390 ? 214.341 285.572 242.414 1.00 18.54  ? 390 TYR E O   1 
ATOM   14314 C  CB  . TYR E 1 390 ? 213.818 286.106 239.344 1.00 17.69  ? 390 TYR E CB  1 
ATOM   14315 C  CG  . TYR E 1 390 ? 214.100 286.333 237.879 1.00 20.13  ? 390 TYR E CG  1 
ATOM   14316 C  CD1 . TYR E 1 390 ? 213.871 287.570 237.296 1.00 18.98  ? 390 TYR E CD1 1 
ATOM   14317 C  CD2 . TYR E 1 390 ? 214.585 285.311 237.078 1.00 18.60  ? 390 TYR E CD2 1 
ATOM   14318 C  CE1 . TYR E 1 390 ? 214.115 287.782 235.960 1.00 19.98  ? 390 TYR E CE1 1 
ATOM   14319 C  CE2 . TYR E 1 390 ? 214.837 285.515 235.741 1.00 20.74  ? 390 TYR E CE2 1 
ATOM   14320 C  CZ  . TYR E 1 390 ? 214.599 286.753 235.186 1.00 24.32  ? 390 TYR E CZ  1 
ATOM   14321 O  OH  . TYR E 1 390 ? 214.847 286.965 233.851 1.00 25.57  ? 390 TYR E OH  1 
ATOM   14322 N  N   . ASP E 1 391 ? 214.123 287.802 242.107 1.00 16.23  ? 391 ASP E N   1 
ATOM   14323 C  CA  . ASP E 1 391 ? 213.423 288.069 243.364 1.00 14.40  ? 391 ASP E CA  1 
ATOM   14324 C  C   . ASP E 1 391 ? 214.212 287.581 244.577 1.00 15.15  ? 391 ASP E C   1 
ATOM   14325 O  O   . ASP E 1 391 ? 213.638 287.150 245.577 1.00 20.87  ? 391 ASP E O   1 
ATOM   14326 C  CB  . ASP E 1 391 ? 212.022 287.453 243.357 1.00 13.19  ? 391 ASP E CB  1 
ATOM   14327 C  CG  . ASP E 1 391 ? 211.190 287.902 242.174 1.00 21.49  ? 391 ASP E CG  1 
ATOM   14328 O  OD1 . ASP E 1 391 ? 210.964 289.120 242.028 1.00 26.48  ? 391 ASP E OD1 1 
ATOM   14329 O  OD2 . ASP E 1 391 ? 210.756 287.032 241.391 1.00 30.86  ? 391 ASP E OD2 1 
ATOM   14330 N  N   . MET E 1 392 ? 215.542 287.654 244.501 1.00 14.90  ? 392 MET E N   1 
ATOM   14331 C  CA  . MET E 1 392 ? 216.341 287.373 245.688 1.00 13.96  ? 392 MET E CA  1 
ATOM   14332 C  C   . MET E 1 392 ? 216.160 288.446 246.752 1.00 18.46  ? 392 MET E C   1 
ATOM   14333 O  O   . MET E 1 392 ? 216.399 288.176 247.934 1.00 23.60  ? 392 MET E O   1 
ATOM   14334 C  CB  . MET E 1 392 ? 217.818 287.229 245.319 1.00 17.82  ? 392 MET E CB  1 
ATOM   14335 C  CG  . MET E 1 392 ? 218.119 286.051 244.401 1.00 16.82  ? 392 MET E CG  1 
ATOM   14336 S  SD  . MET E 1 392 ? 217.773 284.451 245.158 1.00 25.32  ? 392 MET E SD  1 
ATOM   14337 C  CE  . MET E 1 392 ? 219.295 284.134 246.038 1.00 12.13  ? 392 MET E CE  1 
ATOM   14338 N  N   . ALA E 1 393 ? 215.739 289.645 246.361 1.00 19.49  ? 393 ALA E N   1 
ATOM   14339 C  CA  . ALA E 1 393 ? 215.348 290.698 247.288 1.00 13.56  ? 393 ALA E CA  1 
ATOM   14340 C  C   . ALA E 1 393 ? 213.875 291.019 247.078 1.00 19.41  ? 393 ALA E C   1 
ATOM   14341 O  O   . ALA E 1 393 ? 213.453 291.297 245.951 1.00 20.29  ? 393 ALA E O   1 
ATOM   14342 C  CB  . ALA E 1 393 ? 216.197 291.956 247.092 1.00 17.06  ? 393 ALA E CB  1 
ATOM   14343 N  N   . GLY E 1 394 ? 213.099 290.980 248.156 1.00 18.87  ? 394 GLY E N   1 
ATOM   14344 C  CA  . GLY E 1 394 ? 211.691 291.308 248.079 1.00 14.55  ? 394 GLY E CA  1 
ATOM   14345 C  C   . GLY E 1 394 ? 210.830 290.163 247.577 1.00 14.98  ? 394 GLY E C   1 
ATOM   14346 O  O   . GLY E 1 394 ? 211.265 289.018 247.432 1.00 16.09  ? 394 GLY E O   1 
ATOM   14347 N  N   . ASN E 1 395 ? 209.569 290.501 247.302 1.00 13.38  ? 395 ASN E N   1 
ATOM   14348 C  CA  . ASN E 1 395 ? 208.544 289.523 246.954 1.00 14.54  ? 395 ASN E CA  1 
ATOM   14349 C  C   . ASN E 1 395 ? 208.194 288.676 248.170 1.00 13.73  ? 395 ASN E C   1 
ATOM   14350 O  O   . ASN E 1 395 ? 207.355 289.073 248.983 1.00 15.34  ? 395 ASN E O   1 
ATOM   14351 C  CB  . ASN E 1 395 ? 208.988 288.640 245.787 1.00 16.23  ? 395 ASN E CB  1 
ATOM   14352 C  CG  . ASN E 1 395 ? 207.901 288.476 244.743 1.00 15.04  ? 395 ASN E CG  1 
ATOM   14353 O  OD1 . ASN E 1 395 ? 206.981 289.285 244.660 1.00 17.77  ? 395 ASN E OD1 1 
ATOM   14354 N  ND2 . ASN E 1 395 ? 207.997 287.420 243.947 1.00 17.05  ? 395 ASN E ND2 1 
ATOM   14355 N  N   . VAL E 1 396 ? 208.819 287.510 248.305 1.00 14.41  ? 396 VAL E N   1 
ATOM   14356 C  CA  . VAL E 1 396 ? 208.635 286.655 249.470 1.00 13.78  ? 396 VAL E CA  1 
ATOM   14357 C  C   . VAL E 1 396 ? 209.997 286.361 250.081 1.00 13.36  ? 396 VAL E C   1 
ATOM   14358 O  O   . VAL E 1 396 ? 210.976 286.140 249.361 1.00 16.92  ? 396 VAL E O   1 
ATOM   14359 C  CB  . VAL E 1 396 ? 207.902 285.342 249.119 1.00 12.30  ? 396 VAL E CB  1 
ATOM   14360 C  CG1 . VAL E 1 396 ? 206.445 285.621 248.788 1.00 12.23  ? 396 VAL E CG1 1 
ATOM   14361 C  CG2 . VAL E 1 396 ? 208.598 284.625 247.978 1.00 14.90  ? 396 VAL E CG2 1 
ATOM   14362 N  N   . ALA E 1 397 ? 210.058 286.379 251.409 1.00 15.77  ? 397 ALA E N   1 
ATOM   14363 C  CA  . ALA E 1 397 ? 211.239 285.903 252.107 1.00 13.64  ? 397 ALA E CA  1 
ATOM   14364 C  C   . ALA E 1 397 ? 211.333 284.387 251.972 1.00 15.78  ? 397 ALA E C   1 
ATOM   14365 O  O   . ALA E 1 397 ? 210.333 283.695 251.783 1.00 19.00  ? 397 ALA E O   1 
ATOM   14366 C  CB  . ALA E 1 397 ? 211.196 286.309 253.579 1.00 13.09  ? 397 ALA E CB  1 
ATOM   14367 N  N   . GLU E 1 398 ? 212.552 283.867 252.071 1.00 18.35  ? 398 GLU E N   1 
ATOM   14368 C  CA  . GLU E 1 398 ? 212.833 282.496 251.668 1.00 14.10  ? 398 GLU E CA  1 
ATOM   14369 C  C   . GLU E 1 398 ? 213.413 281.692 252.822 1.00 16.01  ? 398 GLU E C   1 
ATOM   14370 O  O   . GLU E 1 398 ? 214.319 282.157 253.520 1.00 22.06  ? 398 GLU E O   1 
ATOM   14371 C  CB  . GLU E 1 398 ? 213.780 282.479 250.468 1.00 18.05  ? 398 GLU E CB  1 
ATOM   14372 C  CG  . GLU E 1 398 ? 213.090 282.856 249.166 1.00 18.19  ? 398 GLU E CG  1 
ATOM   14373 C  CD  . GLU E 1 398 ? 213.980 283.638 248.228 1.00 19.14  ? 398 GLU E CD  1 
ATOM   14374 O  OE1 . GLU E 1 398 ? 215.098 283.170 247.943 1.00 22.34  ? 398 GLU E OE1 1 
ATOM   14375 O  OE2 . GLU E 1 398 ? 213.563 284.725 247.782 1.00 18.86  ? 398 GLU E OE2 1 
ATOM   14376 N  N   . TRP E 1 399 ? 212.884 280.486 253.011 1.00 18.26  ? 399 TRP E N   1 
ATOM   14377 C  CA  . TRP E 1 399 ? 213.401 279.558 254.007 1.00 15.88  ? 399 TRP E CA  1 
ATOM   14378 C  C   . TRP E 1 399 ? 214.808 279.093 253.652 1.00 15.42  ? 399 TRP E C   1 
ATOM   14379 O  O   . TRP E 1 399 ? 215.165 278.946 252.481 1.00 19.17  ? 399 TRP E O   1 
ATOM   14380 C  CB  . TRP E 1 399 ? 212.493 278.333 254.121 1.00 15.78  ? 399 TRP E CB  1 
ATOM   14381 C  CG  . TRP E 1 399 ? 211.187 278.549 254.815 1.00 13.63  ? 399 TRP E CG  1 
ATOM   14382 C  CD1 . TRP E 1 399 ? 209.946 278.512 254.254 1.00 14.20  ? 399 TRP E CD1 1 
ATOM   14383 C  CD2 . TRP E 1 399 ? 210.987 278.772 256.215 1.00 13.85  ? 399 TRP E CD2 1 
ATOM   14384 N  NE1 . TRP E 1 399 ? 208.987 278.728 255.211 1.00 13.57  ? 399 TRP E NE1 1 
ATOM   14385 C  CE2 . TRP E 1 399 ? 209.600 278.888 256.425 1.00 11.39  ? 399 TRP E CE2 1 
ATOM   14386 C  CE3 . TRP E 1 399 ? 211.848 278.897 257.309 1.00 13.96  ? 399 TRP E CE3 1 
ATOM   14387 C  CZ2 . TRP E 1 399 ? 209.055 279.119 257.683 1.00 9.78   ? 399 TRP E CZ2 1 
ATOM   14388 C  CZ3 . TRP E 1 399 ? 211.304 279.126 258.555 1.00 11.51  ? 399 TRP E CZ3 1 
ATOM   14389 C  CH2 . TRP E 1 399 ? 209.922 279.235 258.732 1.00 11.92  ? 399 TRP E CH2 1 
ATOM   14390 N  N   . THR E 1 400 ? 215.610 278.860 254.686 1.00 18.84  ? 400 THR E N   1 
ATOM   14391 C  CA  . THR E 1 400 ? 216.880 278.165 254.562 1.00 17.34  ? 400 THR E CA  1 
ATOM   14392 C  C   . THR E 1 400 ? 216.893 276.985 255.524 1.00 21.78  ? 400 THR E C   1 
ATOM   14393 O  O   . THR E 1 400 ? 216.084 276.905 256.452 1.00 23.33  ? 400 THR E O   1 
ATOM   14394 C  CB  . THR E 1 400 ? 218.075 279.089 254.851 1.00 20.71  ? 400 THR E CB  1 
ATOM   14395 O  OG1 . THR E 1 400 ? 218.179 279.317 256.261 1.00 22.96  ? 400 THR E OG1 1 
ATOM   14396 C  CG2 . THR E 1 400 ? 217.915 280.420 254.135 1.00 14.24  ? 400 THR E CG2 1 
ATOM   14397 N  N   . SER E 1 401 ? 217.826 276.063 255.297 1.00 22.76  ? 401 SER E N   1 
ATOM   14398 C  CA  . SER E 1 401 ? 217.944 274.893 256.156 1.00 19.28  ? 401 SER E CA  1 
ATOM   14399 C  C   . SER E 1 401 ? 218.691 275.178 257.453 1.00 20.86  ? 401 SER E C   1 
ATOM   14400 O  O   . SER E 1 401 ? 218.719 274.313 258.334 1.00 25.02  ? 401 SER E O   1 
ATOM   14401 C  CB  . SER E 1 401 ? 218.637 273.759 255.399 1.00 19.44  ? 401 SER E CB  1 
ATOM   14402 O  OG  . SER E 1 401 ? 219.863 274.191 254.840 1.00 23.92  ? 401 SER E OG  1 
ATOM   14403 N  N   . THR E 1 402 ? 219.279 276.362 257.596 1.00 19.72  ? 402 THR E N   1 
ATOM   14404 C  CA  . THR E 1 402 ? 220.090 276.684 258.762 1.00 20.51  ? 402 THR E CA  1 
ATOM   14405 C  C   . THR E 1 402 ? 219.214 276.966 259.977 1.00 21.54  ? 402 THR E C   1 
ATOM   14406 O  O   . THR E 1 402 ? 218.237 277.716 259.890 1.00 20.23  ? 402 THR E O   1 
ATOM   14407 C  CB  . THR E 1 402 ? 220.980 277.891 258.471 1.00 23.67  ? 402 THR E CB  1 
ATOM   14408 O  OG1 . THR E 1 402 ? 221.468 277.812 257.127 1.00 29.27  ? 402 THR E OG1 1 
ATOM   14409 C  CG2 . THR E 1 402 ? 222.156 277.932 259.431 1.00 20.05  ? 402 THR E CG2 1 
ATOM   14410 N  N   . ALA E 1 403 ? 219.567 276.363 261.108 1.00 22.07  ? 403 ALA E N   1 
ATOM   14411 C  CA  . ALA E 1 403 ? 218.942 276.718 262.372 1.00 18.85  ? 403 ALA E CA  1 
ATOM   14412 C  C   . ALA E 1 403 ? 219.425 278.090 262.824 1.00 21.94  ? 403 ALA E C   1 
ATOM   14413 O  O   . ALA E 1 403 ? 220.581 278.466 262.616 1.00 27.85  ? 403 ALA E O   1 
ATOM   14414 C  CB  . ALA E 1 403 ? 219.255 275.673 263.441 1.00 18.81  ? 403 ALA E CB  1 
ATOM   14415 N  N   . PHE E 1 404 ? 218.529 278.842 263.455 1.00 21.82  ? 404 PHE E N   1 
ATOM   14416 C  CA  . PHE E 1 404 ? 218.838 280.215 263.823 1.00 21.63  ? 404 PHE E CA  1 
ATOM   14417 C  C   . PHE E 1 404 ? 219.618 280.267 265.130 1.00 28.15  ? 404 PHE E C   1 
ATOM   14418 O  O   . PHE E 1 404 ? 219.243 279.628 266.118 1.00 30.66  ? 404 PHE E O   1 
ATOM   14419 C  CB  . PHE E 1 404 ? 217.566 281.048 263.949 1.00 22.18  ? 404 PHE E CB  1 
ATOM   14420 C  CG  . PHE E 1 404 ? 217.810 282.428 264.478 1.00 30.01  ? 404 PHE E CG  1 
ATOM   14421 C  CD1 . PHE E 1 404 ? 218.382 283.399 263.675 1.00 26.89  ? 404 PHE E CD1 1 
ATOM   14422 C  CD2 . PHE E 1 404 ? 217.491 282.750 265.785 1.00 33.36  ? 404 PHE E CD2 1 
ATOM   14423 C  CE1 . PHE E 1 404 ? 218.620 284.665 264.162 1.00 27.30  ? 404 PHE E CE1 1 
ATOM   14424 C  CE2 . PHE E 1 404 ? 217.726 284.014 266.276 1.00 31.37  ? 404 PHE E CE2 1 
ATOM   14425 C  CZ  . PHE E 1 404 ? 218.292 284.973 265.463 1.00 32.72  ? 404 PHE E CZ  1 
ATOM   14426 N  N   . SER E 1 405 ? 220.706 281.032 265.128 1.00 29.11  ? 405 SER E N   1 
ATOM   14427 C  CA  . SER E 1 405 ? 221.485 281.312 266.323 1.00 27.94  ? 405 SER E CA  1 
ATOM   14428 C  C   . SER E 1 405 ? 221.982 282.747 266.246 1.00 34.20  ? 405 SER E C   1 
ATOM   14429 O  O   . SER E 1 405 ? 222.397 283.207 265.180 1.00 38.63  ? 405 SER E O   1 
ATOM   14430 C  CB  . SER E 1 405 ? 222.667 280.346 266.465 1.00 31.33  ? 405 SER E CB  1 
ATOM   14431 O  OG  . SER E 1 405 ? 223.154 280.323 267.795 1.00 37.51  ? 405 SER E OG  1 
ATOM   14432 N  N   . GLU E 1 406 ? 221.931 283.454 267.377 1.00 35.71  ? 406 GLU E N   1 
ATOM   14433 C  CA  . GLU E 1 406 ? 222.393 284.838 267.386 1.00 37.00  ? 406 GLU E CA  1 
ATOM   14434 C  C   . GLU E 1 406 ? 223.872 284.930 267.041 1.00 37.69  ? 406 GLU E C   1 
ATOM   14435 O  O   . GLU E 1 406 ? 224.305 285.904 266.417 1.00 40.68  ? 406 GLU E O   1 
ATOM   14436 C  CB  . GLU E 1 406 ? 222.114 285.479 268.744 1.00 39.52  ? 406 GLU E CB  1 
ATOM   14437 C  CG  . GLU E 1 406 ? 220.670 285.343 269.187 1.00 47.37  ? 406 GLU E CG  1 
ATOM   14438 C  CD  . GLU E 1 406 ? 219.750 286.302 268.460 1.00 60.67  ? 406 GLU E CD  1 
ATOM   14439 O  OE1 . GLU E 1 406 ? 220.254 287.129 267.670 1.00 60.69  ? 406 GLU E OE1 1 
ATOM   14440 O  OE2 . GLU E 1 406 ? 218.522 286.225 268.672 1.00 60.58  ? 406 GLU E OE2 1 
ATOM   14441 N  N   . SER E 1 407 ? 224.658 283.934 267.437 1.00 34.85  ? 407 SER E N   1 
ATOM   14442 C  CA  . SER E 1 407 ? 226.042 283.789 266.997 1.00 35.36  ? 407 SER E CA  1 
ATOM   14443 C  C   . SER E 1 407 ? 226.131 282.460 266.260 1.00 39.37  ? 407 SER E C   1 
ATOM   14444 O  O   . SER E 1 407 ? 226.491 281.434 266.838 1.00 44.68  ? 407 SER E O   1 
ATOM   14445 C  CB  . SER E 1 407 ? 227.012 283.856 268.182 1.00 38.84  ? 407 SER E CB  1 
ATOM   14446 O  OG  . SER E 1 407 ? 226.657 282.923 269.187 1.00 37.48  ? 407 SER E OG  1 
ATOM   14447 N  N   . GLY E 1 408 ? 225.803 282.486 264.971 1.00 37.80  ? 408 GLY E N   1 
ATOM   14448 C  CA  . GLY E 1 408 ? 225.861 281.302 264.141 1.00 27.67  ? 408 GLY E CA  1 
ATOM   14449 C  C   . GLY E 1 408 ? 226.896 281.449 263.050 1.00 31.12  ? 408 GLY E C   1 
ATOM   14450 O  O   . GLY E 1 408 ? 227.491 280.465 262.602 1.00 30.90  ? 408 GLY E O   1 
ATOM   14451 N  N   . LEU E 1 409 ? 227.118 282.690 262.613 1.00 35.45  ? 409 LEU E N   1 
ATOM   14452 C  CA  . LEU E 1 409 ? 228.187 282.952 261.659 1.00 29.41  ? 409 LEU E CA  1 
ATOM   14453 C  C   . LEU E 1 409 ? 229.545 282.599 262.247 1.00 30.16  ? 409 LEU E C   1 
ATOM   14454 O  O   . LEU E 1 409 ? 230.433 282.135 261.524 1.00 36.33  ? 409 LEU E O   1 
ATOM   14455 C  CB  . LEU E 1 409 ? 228.154 284.417 261.224 1.00 30.83  ? 409 LEU E CB  1 
ATOM   14456 C  CG  . LEU E 1 409 ? 227.462 284.716 259.893 1.00 38.55  ? 409 LEU E CG  1 
ATOM   14457 C  CD1 . LEU E 1 409 ? 226.013 284.250 259.922 1.00 30.46  ? 409 LEU E CD1 1 
ATOM   14458 C  CD2 . LEU E 1 409 ? 227.547 286.196 259.560 1.00 36.40  ? 409 LEU E CD2 1 
ATOM   14459 N  N   . LYS E 1 410 ? 229.727 282.816 263.552 1.00 29.75  ? 410 LYS E N   1 
ATOM   14460 C  CA  . LYS E 1 410 ? 230.958 282.414 264.220 1.00 29.87  ? 410 LYS E CA  1 
ATOM   14461 C  C   . LYS E 1 410 ? 231.005 280.915 264.490 1.00 31.15  ? 410 LYS E C   1 
ATOM   14462 O  O   . LYS E 1 410 ? 232.092 280.329 264.504 1.00 31.61  ? 410 LYS E O   1 
ATOM   14463 C  CB  . LYS E 1 410 ? 231.116 283.178 265.535 1.00 38.28  ? 410 LYS E CB  1 
ATOM   14464 C  CG  . LYS E 1 410 ? 231.640 284.592 265.382 1.00 39.69  ? 410 LYS E CG  1 
ATOM   14465 C  CD  . LYS E 1 410 ? 233.042 284.727 265.948 1.00 45.32  ? 410 LYS E CD  1 
ATOM   14466 C  CE  . LYS E 1 410 ? 233.613 286.104 265.664 1.00 44.79  ? 410 LYS E CE  1 
ATOM   14467 N  NZ  . LYS E 1 410 ? 233.818 286.881 266.916 1.00 44.65  ? 410 LYS E NZ  1 
ATOM   14468 N  N   . GLN E 1 411 ? 229.854 280.284 264.713 1.00 32.03  ? 411 GLN E N   1 
ATOM   14469 C  CA  . GLN E 1 411 ? 229.804 278.869 265.054 1.00 28.33  ? 411 GLN E CA  1 
ATOM   14470 C  C   . GLN E 1 411 ? 229.840 277.950 263.841 1.00 29.61  ? 411 GLN E C   1 
ATOM   14471 O  O   . GLN E 1 411 ? 230.069 276.748 264.005 1.00 33.86  ? 411 GLN E O   1 
ATOM   14472 C  CB  . GLN E 1 411 ? 228.547 278.566 265.875 1.00 27.38  ? 411 GLN E CB  1 
ATOM   14473 C  CG  . GLN E 1 411 ? 228.624 279.026 267.316 1.00 29.49  ? 411 GLN E CG  1 
ATOM   14474 C  CD  . GLN E 1 411 ? 227.286 278.962 268.015 1.00 38.86  ? 411 GLN E CD  1 
ATOM   14475 O  OE1 . GLN E 1 411 ? 226.239 278.947 267.373 1.00 41.85  ? 411 GLN E OE1 1 
ATOM   14476 N  NE2 . GLN E 1 411 ? 227.313 278.935 269.342 1.00 36.48  ? 411 GLN E NE2 1 
ATOM   14477 N  N   . MET E 1 412 ? 229.623 278.474 262.639 1.00 29.90  ? 412 MET E N   1 
ATOM   14478 C  CA  . MET E 1 412 ? 229.656 277.653 261.441 1.00 29.81  ? 412 MET E CA  1 
ATOM   14479 C  C   . MET E 1 412 ? 231.092 277.443 260.967 1.00 32.15  ? 412 MET E C   1 
ATOM   14480 O  O   . MET E 1 412 ? 232.040 278.057 261.461 1.00 32.57  ? 412 MET E O   1 
ATOM   14481 C  CB  . MET E 1 412 ? 228.813 278.287 260.338 1.00 24.14  ? 412 MET E CB  1 
ATOM   14482 C  CG  . MET E 1 412 ? 227.339 277.940 260.421 1.00 28.05  ? 412 MET E CG  1 
ATOM   14483 S  SD  . MET E 1 412 ? 226.299 279.002 259.403 1.00 43.44  ? 412 MET E SD  1 
ATOM   14484 C  CE  . MET E 1 412 ? 227.531 279.979 258.547 1.00 24.90  ? 412 MET E CE  1 
ATOM   14485 N  N   . SER E 1 413 ? 231.245 276.553 259.991 1.00 30.27  ? 413 SER E N   1 
ATOM   14486 C  CA  . SER E 1 413 ? 232.550 276.242 259.433 1.00 28.76  ? 413 SER E CA  1 
ATOM   14487 C  C   . SER E 1 413 ? 232.935 277.255 258.355 1.00 31.34  ? 413 SER E C   1 
ATOM   14488 O  O   . SER E 1 413 ? 232.123 278.059 257.892 1.00 30.41  ? 413 SER E O   1 
ATOM   14489 C  CB  . SER E 1 413 ? 232.562 274.828 258.857 1.00 30.12  ? 413 SER E CB  1 
ATOM   14490 O  OG  . SER E 1 413 ? 233.886 274.357 258.678 1.00 30.07  ? 413 SER E OG  1 
ATOM   14491 N  N   . ASP E 1 414 ? 234.207 277.202 257.958 1.00 33.11  ? 414 ASP E N   1 
ATOM   14492 C  CA  . ASP E 1 414 ? 234.717 278.084 256.915 1.00 32.27  ? 414 ASP E CA  1 
ATOM   14493 C  C   . ASP E 1 414 ? 234.294 277.643 255.520 1.00 27.29  ? 414 ASP E C   1 
ATOM   14494 O  O   . ASP E 1 414 ? 234.067 278.489 254.649 1.00 22.76  ? 414 ASP E O   1 
ATOM   14495 C  CB  . ASP E 1 414 ? 236.242 278.153 256.990 1.00 31.77  ? 414 ASP E CB  1 
ATOM   14496 C  CG  . ASP E 1 414 ? 236.762 279.563 256.879 1.00 37.25  ? 414 ASP E CG  1 
ATOM   14497 O  OD1 . ASP E 1 414 ? 236.044 280.412 256.316 1.00 37.52  ? 414 ASP E OD1 1 
ATOM   14498 O  OD2 . ASP E 1 414 ? 237.889 279.823 257.347 1.00 41.18  ? 414 ASP E OD2 1 
ATOM   14499 N  N   . ILE E 1 415 ? 234.194 276.338 255.288 1.00 26.58  ? 415 ILE E N   1 
ATOM   14500 C  CA  . ILE E 1 415 ? 233.880 275.778 253.979 1.00 25.32  ? 415 ILE E CA  1 
ATOM   14501 C  C   . ILE E 1 415 ? 232.519 275.106 254.060 1.00 28.04  ? 415 ILE E C   1 
ATOM   14502 O  O   . ILE E 1 415 ? 232.250 274.345 254.998 1.00 30.85  ? 415 ILE E O   1 
ATOM   14503 C  CB  . ILE E 1 415 ? 234.962 274.786 253.518 1.00 27.69  ? 415 ILE E CB  1 
ATOM   14504 C  CG1 . ILE E 1 415 ? 234.406 273.849 252.444 1.00 29.88  ? 415 ILE E CG1 1 
ATOM   14505 C  CG2 . ILE E 1 415 ? 235.511 274.002 254.700 1.00 24.34  ? 415 ILE E CG2 1 
ATOM   14506 C  CD1 . ILE E 1 415 ? 235.366 272.761 252.029 1.00 36.36  ? 415 ILE E CD1 1 
ATOM   14507 N  N   . ASN E 1 416 ? 231.662 275.390 253.082 1.00 25.24  ? 416 ASN E N   1 
ATOM   14508 C  CA  . ASN E 1 416 ? 230.299 274.876 253.040 1.00 22.20  ? 416 ASN E CA  1 
ATOM   14509 C  C   . ASN E 1 416 ? 229.597 275.065 254.389 1.00 26.34  ? 416 ASN E C   1 
ATOM   14510 O  O   . ASN E 1 416 ? 229.091 274.104 254.970 1.00 25.54  ? 416 ASN E O   1 
ATOM   14511 C  CB  . ASN E 1 416 ? 230.279 273.409 252.633 1.00 25.51  ? 416 ASN E CB  1 
ATOM   14512 C  CG  . ASN E 1 416 ? 230.627 273.205 251.174 1.00 27.10  ? 416 ASN E CG  1 
ATOM   14513 O  OD1 . ASN E 1 416 ? 230.521 274.123 250.362 1.00 28.39  ? 416 ASN E OD1 1 
ATOM   14514 N  ND2 . ASN E 1 416 ? 231.044 271.994 250.832 1.00 28.76  ? 416 ASN E ND2 1 
ATOM   14515 N  N   . PRO E 1 417 ? 229.550 276.291 254.905 1.00 27.18  ? 417 PRO E N   1 
ATOM   14516 C  CA  . PRO E 1 417 ? 229.041 276.497 256.265 1.00 24.07  ? 417 PRO E CA  1 
ATOM   14517 C  C   . PRO E 1 417 ? 227.600 276.032 256.401 1.00 24.28  ? 417 PRO E C   1 
ATOM   14518 O  O   . PRO E 1 417 ? 226.774 276.229 255.509 1.00 31.33  ? 417 PRO E O   1 
ATOM   14519 C  CB  . PRO E 1 417 ? 229.167 278.012 256.468 1.00 21.85  ? 417 PRO E CB  1 
ATOM   14520 C  CG  . PRO E 1 417 ? 230.064 278.491 255.372 1.00 21.39  ? 417 PRO E CG  1 
ATOM   14521 C  CD  . PRO E 1 417 ? 229.860 277.561 254.231 1.00 23.60  ? 417 PRO E CD  1 
ATOM   14522 N  N   . GLU E 1 418 ? 227.304 275.413 257.541 1.00 26.26  ? 418 GLU E N   1 
ATOM   14523 C  CA  . GLU E 1 418 ? 225.959 274.937 257.822 1.00 22.29  ? 418 GLU E CA  1 
ATOM   14524 C  C   . GLU E 1 418 ? 225.790 274.785 259.325 1.00 21.74  ? 418 GLU E C   1 
ATOM   14525 O  O   . GLU E 1 418 ? 226.692 274.304 260.013 1.00 27.13  ? 418 GLU E O   1 
ATOM   14526 C  CB  . GLU E 1 418 ? 225.678 273.606 257.112 1.00 19.66  ? 418 GLU E CB  1 
ATOM   14527 C  CG  . GLU E 1 418 ? 224.346 272.940 257.464 1.00 29.04  ? 418 GLU E CG  1 
ATOM   14528 C  CD  . GLU E 1 418 ? 223.134 273.856 257.332 1.00 28.16  ? 418 GLU E CD  1 
ATOM   14529 O  OE1 . GLU E 1 418 ? 223.293 275.093 257.347 1.00 27.48  ? 418 GLU E OE1 1 
ATOM   14530 O  OE2 . GLU E 1 418 ? 222.010 273.327 257.211 1.00 26.75  ? 418 GLU E OE2 1 
ATOM   14531 N  N   . LEU E 1 419 ? 224.632 275.203 259.822 1.00 24.13  ? 419 LEU E N   1 
ATOM   14532 C  CA  . LEU E 1 419 ? 224.238 275.002 261.213 1.00 23.30  ? 419 LEU E CA  1 
ATOM   14533 C  C   . LEU E 1 419 ? 222.921 274.240 261.182 1.00 24.16  ? 419 LEU E C   1 
ATOM   14534 O  O   . LEU E 1 419 ? 221.852 274.835 261.016 1.00 26.74  ? 419 LEU E O   1 
ATOM   14535 C  CB  . LEU E 1 419 ? 224.112 276.328 261.955 1.00 27.65  ? 419 LEU E CB  1 
ATOM   14536 C  CG  . LEU E 1 419 ? 224.385 276.271 263.458 1.00 31.62  ? 419 LEU E CG  1 
ATOM   14537 C  CD1 . LEU E 1 419 ? 225.827 275.873 263.728 1.00 27.61  ? 419 LEU E CD1 1 
ATOM   14538 C  CD2 . LEU E 1 419 ? 224.063 277.604 264.111 1.00 31.92  ? 419 LEU E CD2 1 
ATOM   14539 N  N   . GLU E 1 420 ? 223.002 272.925 261.341 1.00 26.94  ? 420 GLU E N   1 
ATOM   14540 C  CA  . GLU E 1 420 ? 221.870 272.031 261.154 1.00 26.38  ? 420 GLU E CA  1 
ATOM   14541 C  C   . GLU E 1 420 ? 221.413 271.494 262.501 1.00 27.62  ? 420 GLU E C   1 
ATOM   14542 O  O   . GLU E 1 420 ? 222.218 270.945 263.260 1.00 40.31  ? 420 GLU E O   1 
ATOM   14543 C  CB  . GLU E 1 420 ? 222.245 270.877 260.224 1.00 29.31  ? 420 GLU E CB  1 
ATOM   14544 C  CG  . GLU E 1 420 ? 221.065 270.182 259.581 1.00 38.57  ? 420 GLU E CG  1 
ATOM   14545 C  CD  . GLU E 1 420 ? 220.810 268.816 260.178 1.00 48.85  ? 420 GLU E CD  1 
ATOM   14546 O  OE1 . GLU E 1 420 ? 221.786 268.068 260.393 1.00 54.58  ? 420 GLU E OE1 1 
ATOM   14547 O  OE2 . GLU E 1 420 ? 219.633 268.488 260.432 1.00 50.14  ? 420 GLU E OE2 1 
ATOM   14548 N  N   . TYR E 1 421 ? 220.128 271.656 262.795 1.00 28.99  ? 421 TYR E N   1 
ATOM   14549 C  CA  . TYR E 1 421 ? 219.540 271.130 264.017 1.00 24.78  ? 421 TYR E CA  1 
ATOM   14550 C  C   . TYR E 1 421 ? 218.241 270.416 263.687 1.00 25.24  ? 421 TYR E C   1 
ATOM   14551 O  O   . TYR E 1 421 ? 217.362 270.987 263.035 1.00 31.28  ? 421 TYR E O   1 
ATOM   14552 C  CB  . TYR E 1 421 ? 219.279 272.242 265.034 1.00 26.18  ? 421 TYR E CB  1 
ATOM   14553 C  CG  . TYR E 1 421 ? 218.823 271.726 266.376 1.00 26.14  ? 421 TYR E CG  1 
ATOM   14554 C  CD1 . TYR E 1 421 ? 219.568 270.781 267.065 1.00 26.20  ? 421 TYR E CD1 1 
ATOM   14555 C  CD2 . TYR E 1 421 ? 217.641 272.171 266.946 1.00 24.93  ? 421 TYR E CD2 1 
ATOM   14556 C  CE1 . TYR E 1 421 ? 219.156 270.302 268.287 1.00 28.14  ? 421 TYR E CE1 1 
ATOM   14557 C  CE2 . TYR E 1 421 ? 217.221 271.699 268.169 1.00 25.76  ? 421 TYR E CE2 1 
ATOM   14558 C  CZ  . TYR E 1 421 ? 217.982 270.764 268.835 1.00 28.91  ? 421 TYR E CZ  1 
ATOM   14559 O  OH  . TYR E 1 421 ? 217.567 270.290 270.054 1.00 33.69  ? 421 TYR E OH  1 
ATOM   14560 N  N   . LYS E 1 422 ? 218.122 269.172 264.138 1.00 26.84  ? 422 LYS E N   1 
ATOM   14561 C  CA  . LYS E 1 422 ? 216.876 268.416 264.052 1.00 26.28  ? 422 LYS E CA  1 
ATOM   14562 C  C   . LYS E 1 422 ? 216.247 268.439 265.439 1.00 24.57  ? 422 LYS E C   1 
ATOM   14563 O  O   . LYS E 1 422 ? 216.609 267.645 266.310 1.00 29.78  ? 422 LYS E O   1 
ATOM   14564 C  CB  . LYS E 1 422 ? 217.131 266.995 263.563 1.00 25.15  ? 422 LYS E CB  1 
ATOM   14565 C  CG  . LYS E 1 422 ? 217.251 266.878 262.056 1.00 28.61  ? 422 LYS E CG  1 
ATOM   14566 C  CD  . LYS E 1 422 ? 217.582 265.460 261.633 1.00 30.46  ? 422 LYS E CD  1 
ATOM   14567 C  CE  . LYS E 1 422 ? 218.969 265.379 261.028 1.00 33.40  ? 422 LYS E CE  1 
ATOM   14568 N  NZ  . LYS E 1 422 ? 218.937 265.504 259.547 1.00 35.61  ? 422 LYS E NZ  1 
ATOM   14569 N  N   . ALA E 1 423 ? 215.307 269.355 265.641 1.00 25.45  ? 423 ALA E N   1 
ATOM   14570 C  CA  . ALA E 1 423 ? 214.739 269.565 266.964 1.00 27.16  ? 423 ALA E CA  1 
ATOM   14571 C  C   . ALA E 1 423 ? 213.925 268.360 267.413 1.00 28.20  ? 423 ALA E C   1 
ATOM   14572 O  O   . ALA E 1 423 ? 213.203 267.744 266.623 1.00 30.55  ? 423 ALA E O   1 
ATOM   14573 C  CB  . ALA E 1 423 ? 213.864 270.817 266.970 1.00 23.33  ? 423 ALA E CB  1 
ATOM   14574 N  N   . ALA E 1 424 ? 214.049 268.022 268.692 1.00 28.59  ? 424 ALA E N   1 
ATOM   14575 C  CA  . ALA E 1 424 ? 213.197 267.004 269.284 1.00 25.77  ? 424 ALA E CA  1 
ATOM   14576 C  C   . ALA E 1 424 ? 211.774 267.531 269.435 1.00 32.27  ? 424 ALA E C   1 
ATOM   14577 O  O   . ALA E 1 424 ? 211.549 268.727 269.632 1.00 36.88  ? 424 ALA E O   1 
ATOM   14578 C  CB  . ALA E 1 424 ? 213.745 266.567 270.641 1.00 25.49  ? 424 ALA E CB  1 
ATOM   14579 N  N   . LEU E 1 425 ? 210.805 266.619 269.338 1.00 29.27  ? 425 LEU E N   1 
ATOM   14580 C  CA  . LEU E 1 425 ? 209.406 267.026 269.412 1.00 33.25  ? 425 LEU E CA  1 
ATOM   14581 C  C   . LEU E 1 425 ? 209.080 267.692 270.740 1.00 36.86  ? 425 LEU E C   1 
ATOM   14582 O  O   . LEU E 1 425 ? 208.236 268.594 270.790 1.00 40.36  ? 425 LEU E O   1 
ATOM   14583 C  CB  . LEU E 1 425 ? 208.495 265.821 269.184 1.00 35.91  ? 425 LEU E CB  1 
ATOM   14584 C  CG  . LEU E 1 425 ? 208.177 265.519 267.720 1.00 33.69  ? 425 LEU E CG  1 
ATOM   14585 C  CD1 . LEU E 1 425 ? 207.659 264.105 267.572 1.00 32.37  ? 425 LEU E CD1 1 
ATOM   14586 C  CD2 . LEU E 1 425 ? 207.176 266.521 267.171 1.00 35.15  ? 425 LEU E CD2 1 
ATOM   14587 N  N   . THR E 1 426 ? 209.734 267.273 271.821 1.00 35.23  ? 426 THR E N   1 
ATOM   14588 C  CA  . THR E 1 426 ? 209.514 267.849 273.138 1.00 33.06  ? 426 THR E CA  1 
ATOM   14589 C  C   . THR E 1 426 ? 210.553 268.904 273.496 1.00 36.08  ? 426 THR E C   1 
ATOM   14590 O  O   . THR E 1 426 ? 210.618 269.330 274.653 1.00 41.06  ? 426 THR E O   1 
ATOM   14591 C  CB  . THR E 1 426 ? 209.495 266.750 274.202 1.00 40.58  ? 426 THR E CB  1 
ATOM   14592 O  OG1 . THR E 1 426 ? 210.790 266.147 274.292 1.00 52.09  ? 426 THR E OG1 1 
ATOM   14593 C  CG2 . THR E 1 426 ? 208.467 265.688 273.848 1.00 37.07  ? 426 THR E CG2 1 
ATOM   14594 N  N   . ASP E 1 427 ? 211.365 269.332 272.534 1.00 30.86  ? 427 ASP E N   1 
ATOM   14595 C  CA  . ASP E 1 427 ? 212.270 270.443 272.767 1.00 27.15  ? 427 ASP E CA  1 
ATOM   14596 C  C   . ASP E 1 427 ? 211.469 271.724 272.989 1.00 30.48  ? 427 ASP E C   1 
ATOM   14597 O  O   . ASP E 1 427 ? 210.346 271.857 272.495 1.00 36.05  ? 427 ASP E O   1 
ATOM   14598 C  CB  . ASP E 1 427 ? 213.217 270.625 271.584 1.00 26.88  ? 427 ASP E CB  1 
ATOM   14599 C  CG  . ASP E 1 427 ? 214.544 269.931 271.787 1.00 32.91  ? 427 ASP E CG  1 
ATOM   14600 O  OD1 . ASP E 1 427 ? 214.916 269.684 272.952 1.00 38.75  ? 427 ASP E OD1 1 
ATOM   14601 O  OD2 . ASP E 1 427 ? 215.217 269.633 270.780 1.00 33.01  ? 427 ASP E OD2 1 
ATOM   14602 N  N   . PRO E 1 428 ? 212.016 272.680 273.737 1.00 27.43  ? 428 PRO E N   1 
ATOM   14603 C  CA  . PRO E 1 428 ? 211.330 273.966 273.889 1.00 25.78  ? 428 PRO E CA  1 
ATOM   14604 C  C   . PRO E 1 428 ? 211.159 274.655 272.544 1.00 25.39  ? 428 PRO E C   1 
ATOM   14605 O  O   . PRO E 1 428 ? 211.986 274.523 271.641 1.00 27.54  ? 428 PRO E O   1 
ATOM   14606 C  CB  . PRO E 1 428 ? 212.256 274.762 274.819 1.00 25.35  ? 428 PRO E CB  1 
ATOM   14607 C  CG  . PRO E 1 428 ? 213.561 274.034 274.802 1.00 27.22  ? 428 PRO E CG  1 
ATOM   14608 C  CD  . PRO E 1 428 ? 213.235 272.600 274.555 1.00 25.06  ? 428 PRO E CD  1 
ATOM   14609 N  N   . TYR E 1 429 ? 210.060 275.401 272.421 1.00 23.94  ? 429 TYR E N   1 
ATOM   14610 C  CA  . TYR E 1 429 ? 209.739 276.054 271.157 1.00 22.87  ? 429 TYR E CA  1 
ATOM   14611 C  C   . TYR E 1 429 ? 210.876 276.946 270.674 1.00 23.93  ? 429 TYR E C   1 
ATOM   14612 O  O   . TYR E 1 429 ? 211.037 277.144 269.465 1.00 26.09  ? 429 TYR E O   1 
ATOM   14613 C  CB  . TYR E 1 429 ? 208.455 276.868 271.308 1.00 19.74  ? 429 TYR E CB  1 
ATOM   14614 C  CG  . TYR E 1 429 ? 207.735 277.147 270.012 1.00 21.06  ? 429 TYR E CG  1 
ATOM   14615 C  CD1 . TYR E 1 429 ? 207.577 276.157 269.053 1.00 19.06  ? 429 TYR E CD1 1 
ATOM   14616 C  CD2 . TYR E 1 429 ? 207.206 278.402 269.750 1.00 15.76  ? 429 TYR E CD2 1 
ATOM   14617 C  CE1 . TYR E 1 429 ? 206.915 276.411 267.871 1.00 16.45  ? 429 TYR E CE1 1 
ATOM   14618 C  CE2 . TYR E 1 429 ? 206.545 278.664 268.574 1.00 14.48  ? 429 TYR E CE2 1 
ATOM   14619 C  CZ  . TYR E 1 429 ? 206.402 277.667 267.638 1.00 16.87  ? 429 TYR E CZ  1 
ATOM   14620 O  OH  . TYR E 1 429 ? 205.742 277.932 266.463 1.00 24.12  ? 429 TYR E OH  1 
ATOM   14621 N  N   . ILE E 1 430 ? 211.669 277.494 271.598 1.00 25.77  ? 430 ILE E N   1 
ATOM   14622 C  CA  . ILE E 1 430 ? 212.722 278.435 271.237 1.00 27.33  ? 430 ILE E CA  1 
ATOM   14623 C  C   . ILE E 1 430 ? 213.797 277.801 270.364 1.00 28.34  ? 430 ILE E C   1 
ATOM   14624 O  O   . ILE E 1 430 ? 214.528 278.515 269.670 1.00 27.70  ? 430 ILE E O   1 
ATOM   14625 C  CB  . ILE E 1 430 ? 213.349 279.037 272.510 1.00 26.95  ? 430 ILE E CB  1 
ATOM   14626 C  CG1 . ILE E 1 430 ? 214.287 280.187 272.147 1.00 29.91  ? 430 ILE E CG1 1 
ATOM   14627 C  CG2 . ILE E 1 430 ? 214.092 277.968 273.291 1.00 25.37  ? 430 ILE E CG2 1 
ATOM   14628 C  CD1 . ILE E 1 430 ? 214.139 281.395 273.035 1.00 32.48  ? 430 ILE E CD1 1 
ATOM   14629 N  N   . LEU E 1 431 ? 213.920 276.477 270.384 1.00 26.34  ? 431 LEU E N   1 
ATOM   14630 C  CA  . LEU E 1 431 ? 214.961 275.781 269.641 1.00 24.14  ? 431 LEU E CA  1 
ATOM   14631 C  C   . LEU E 1 431 ? 214.546 275.419 268.222 1.00 22.66  ? 431 LEU E C   1 
ATOM   14632 O  O   . LEU E 1 431 ? 215.326 274.779 267.511 1.00 27.10  ? 431 LEU E O   1 
ATOM   14633 C  CB  . LEU E 1 431 ? 215.377 274.507 270.386 1.00 24.69  ? 431 LEU E CB  1 
ATOM   14634 C  CG  . LEU E 1 431 ? 216.015 274.672 271.765 1.00 26.75  ? 431 LEU E CG  1 
ATOM   14635 C  CD1 . LEU E 1 431 ? 216.439 273.326 272.321 1.00 25.76  ? 431 LEU E CD1 1 
ATOM   14636 C  CD2 . LEU E 1 431 ? 217.199 275.619 271.702 1.00 29.03  ? 431 LEU E CD2 1 
ATOM   14637 N  N   . LYS E 1 432 ? 213.348 275.810 267.789 1.00 22.66  ? 432 LYS E N   1 
ATOM   14638 C  CA  . LYS E 1 432 ? 212.809 275.399 266.499 1.00 19.64  ? 432 LYS E CA  1 
ATOM   14639 C  C   . LYS E 1 432 ? 212.720 276.555 265.508 1.00 19.14  ? 432 LYS E C   1 
ATOM   14640 O  O   . LYS E 1 432 ? 211.837 276.576 264.649 1.00 23.24  ? 432 LYS E O   1 
ATOM   14641 C  CB  . LYS E 1 432 ? 211.440 274.747 266.685 1.00 20.60  ? 432 LYS E CB  1 
ATOM   14642 C  CG  . LYS E 1 432 ? 211.364 273.831 267.889 1.00 24.10  ? 432 LYS E CG  1 
ATOM   14643 C  CD  . LYS E 1 432 ? 210.192 272.877 267.790 1.00 26.89  ? 432 LYS E CD  1 
ATOM   14644 C  CE  . LYS E 1 432 ? 210.240 271.842 268.899 1.00 29.00  ? 432 LYS E CE  1 
ATOM   14645 N  NZ  . LYS E 1 432 ? 208.897 271.563 269.468 1.00 34.71  ? 432 LYS E NZ  1 
ATOM   14646 N  N   . GLN E 1 433 ? 213.632 277.515 265.604 1.00 18.15  ? 433 GLN E N   1 
ATOM   14647 C  CA  . GLN E 1 433 ? 213.654 278.661 264.708 1.00 18.24  ? 433 GLN E CA  1 
ATOM   14648 C  C   . GLN E 1 433 ? 214.648 278.430 263.578 1.00 17.26  ? 433 GLN E C   1 
ATOM   14649 O  O   . GLN E 1 433 ? 215.741 277.899 263.794 1.00 21.49  ? 433 GLN E O   1 
ATOM   14650 C  CB  . GLN E 1 433 ? 214.013 279.939 265.465 1.00 21.45  ? 433 GLN E CB  1 
ATOM   14651 C  CG  . GLN E 1 433 ? 213.125 280.211 266.661 1.00 23.03  ? 433 GLN E CG  1 
ATOM   14652 C  CD  . GLN E 1 433 ? 213.069 281.678 267.015 1.00 29.66  ? 433 GLN E CD  1 
ATOM   14653 O  OE1 . GLN E 1 433 ? 212.409 282.467 266.340 1.00 30.27  ? 433 GLN E OE1 1 
ATOM   14654 N  NE2 . GLN E 1 433 ? 213.773 282.057 268.073 1.00 29.18  ? 433 GLN E NE2 1 
ATOM   14655 N  N   . LYS E 1 434 ? 214.259 278.835 262.374 1.00 16.27  ? 434 LYS E N   1 
ATOM   14656 C  CA  . LYS E 1 434 ? 215.060 278.666 261.175 1.00 14.21  ? 434 LYS E CA  1 
ATOM   14657 C  C   . LYS E 1 434 ? 215.273 280.014 260.503 1.00 16.13  ? 434 LYS E C   1 
ATOM   14658 O  O   . LYS E 1 434 ? 214.399 280.889 260.530 1.00 21.75  ? 434 LYS E O   1 
ATOM   14659 C  CB  . LYS E 1 434 ? 214.397 277.697 260.192 1.00 11.91  ? 434 LYS E CB  1 
ATOM   14660 C  CG  . LYS E 1 434 ? 213.882 276.423 260.827 1.00 12.99  ? 434 LYS E CG  1 
ATOM   14661 C  CD  . LYS E 1 434 ? 215.015 275.467 261.139 1.00 12.11  ? 434 LYS E CD  1 
ATOM   14662 C  CE  . LYS E 1 434 ? 214.517 274.291 261.951 1.00 12.41  ? 434 LYS E CE  1 
ATOM   14663 N  NZ  . LYS E 1 434 ? 215.633 273.452 262.456 1.00 15.86  ? 434 LYS E NZ  1 
ATOM   14664 N  N   . VAL E 1 435 ? 216.450 280.159 259.893 1.00 19.08  ? 435 VAL E N   1 
ATOM   14665 C  CA  . VAL E 1 435 ? 216.853 281.420 259.285 1.00 19.69  ? 435 VAL E CA  1 
ATOM   14666 C  C   . VAL E 1 435 ? 216.027 281.693 258.036 1.00 17.68  ? 435 VAL E C   1 
ATOM   14667 O  O   . VAL E 1 435 ? 215.729 280.787 257.248 1.00 17.42  ? 435 VAL E O   1 
ATOM   14668 C  CB  . VAL E 1 435 ? 218.356 281.399 258.961 1.00 18.87  ? 435 VAL E CB  1 
ATOM   14669 C  CG1 . VAL E 1 435 ? 218.794 282.736 258.394 1.00 19.96  ? 435 VAL E CG1 1 
ATOM   14670 C  CG2 . VAL E 1 435 ? 219.163 281.054 260.203 1.00 20.77  ? 435 VAL E CG2 1 
ATOM   14671 N  N   . VAL E 1 436 ? 215.657 282.957 257.854 1.00 19.07  ? 436 VAL E N   1 
ATOM   14672 C  CA  . VAL E 1 436 ? 214.913 283.429 256.694 1.00 17.01  ? 436 VAL E CA  1 
ATOM   14673 C  C   . VAL E 1 436 ? 215.700 284.565 256.054 1.00 18.23  ? 436 VAL E C   1 
ATOM   14674 O  O   . VAL E 1 436 ? 216.271 285.412 256.754 1.00 21.82  ? 436 VAL E O   1 
ATOM   14675 C  CB  . VAL E 1 436 ? 213.489 283.885 257.075 1.00 18.79  ? 436 VAL E CB  1 
ATOM   14676 C  CG1 . VAL E 1 436 ? 212.783 284.489 255.877 1.00 19.01  ? 436 VAL E CG1 1 
ATOM   14677 C  CG2 . VAL E 1 436 ? 212.693 282.713 257.619 1.00 12.84  ? 436 VAL E CG2 1 
ATOM   14678 N  N   . ARG E 1 437 ? 215.747 284.570 254.724 1.00 15.98  ? 437 ARG E N   1 
ATOM   14679 C  CA  . ARG E 1 437 ? 216.627 285.456 253.979 1.00 16.18  ? 437 ARG E CA  1 
ATOM   14680 C  C   . ARG E 1 437 ? 215.853 286.197 252.900 1.00 16.55  ? 437 ARG E C   1 
ATOM   14681 O  O   . ARG E 1 437 ? 214.913 285.663 252.306 1.00 20.38  ? 437 ARG E O   1 
ATOM   14682 C  CB  . ARG E 1 437 ? 217.773 284.674 253.327 1.00 14.78  ? 437 ARG E CB  1 
ATOM   14683 C  CG  . ARG E 1 437 ? 218.833 284.208 254.303 1.00 17.75  ? 437 ARG E CG  1 
ATOM   14684 C  CD  . ARG E 1 437 ? 219.063 285.224 255.402 1.00 19.60  ? 437 ARG E CD  1 
ATOM   14685 N  NE  . ARG E 1 437 ? 220.412 285.142 255.947 1.00 26.45  ? 437 ARG E NE  1 
ATOM   14686 C  CZ  . ARG E 1 437 ? 221.481 285.703 255.403 1.00 25.01  ? 437 ARG E CZ  1 
ATOM   14687 N  NH1 . ARG E 1 437 ? 221.400 286.413 254.290 1.00 26.16  ? 437 ARG E NH1 1 
ATOM   14688 N  NH2 . ARG E 1 437 ? 222.662 285.549 255.992 1.00 25.02  ? 437 ARG E NH2 1 
ATOM   14689 N  N   . GLY E 1 438 ? 216.260 287.440 252.653 1.00 15.42  ? 438 GLY E N   1 
ATOM   14690 C  CA  . GLY E 1 438 ? 215.830 288.148 251.465 1.00 15.01  ? 438 GLY E CA  1 
ATOM   14691 C  C   . GLY E 1 438 ? 214.915 289.335 251.675 1.00 17.79  ? 438 GLY E C   1 
ATOM   14692 O  O   . GLY E 1 438 ? 215.039 290.340 250.971 1.00 24.93  ? 438 GLY E O   1 
ATOM   14693 N  N   . GLY E 1 439 ? 214.000 289.241 252.629 1.00 18.34  ? 439 GLY E N   1 
ATOM   14694 C  CA  . GLY E 1 439 ? 212.956 290.231 252.766 1.00 12.17  ? 439 GLY E CA  1 
ATOM   14695 C  C   . GLY E 1 439 ? 211.798 289.963 251.820 1.00 15.00  ? 439 GLY E C   1 
ATOM   14696 O  O   . GLY E 1 439 ? 211.906 289.223 250.845 1.00 18.22  ? 439 GLY E O   1 
ATOM   14697 N  N   . SER E 1 440 ? 210.664 290.593 252.119 1.00 15.01  ? 440 SER E N   1 
ATOM   14698 C  CA  . SER E 1 440 ? 209.443 290.310 251.375 1.00 11.34  ? 440 SER E CA  1 
ATOM   14699 C  C   . SER E 1 440 ? 208.733 291.574 250.908 1.00 13.64  ? 440 SER E C   1 
ATOM   14700 O  O   . SER E 1 440 ? 209.252 292.685 251.052 1.00 15.18  ? 440 SER E O   1 
ATOM   14701 C  CB  . SER E 1 440 ? 208.490 289.476 252.230 1.00 13.02  ? 440 SER E CB  1 
ATOM   14702 O  OG  . SER E 1 440 ? 207.919 290.269 253.254 1.00 15.26  ? 440 SER E OG  1 
ATOM   14703 N  N   . TRP E 1 441 ? 207.530 291.398 250.357 1.00 14.71  ? 441 TRP E N   1 
ATOM   14704 C  CA  . TRP E 1 441 ? 206.733 292.509 249.851 1.00 11.60  ? 441 TRP E CA  1 
ATOM   14705 C  C   . TRP E 1 441 ? 206.324 293.489 250.941 1.00 13.00  ? 441 TRP E C   1 
ATOM   14706 O  O   . TRP E 1 441 ? 205.930 294.617 250.627 1.00 16.20  ? 441 TRP E O   1 
ATOM   14707 C  CB  . TRP E 1 441 ? 205.482 291.968 249.161 1.00 11.72  ? 441 TRP E CB  1 
ATOM   14708 C  CG  . TRP E 1 441 ? 204.657 291.078 250.053 1.00 12.66  ? 441 TRP E CG  1 
ATOM   14709 C  CD1 . TRP E 1 441 ? 204.809 289.736 250.230 1.00 13.03  ? 441 TRP E CD1 1 
ATOM   14710 C  CD2 . TRP E 1 441 ? 203.560 291.469 250.890 1.00 13.06  ? 441 TRP E CD2 1 
ATOM   14711 N  NE1 . TRP E 1 441 ? 203.878 289.266 251.121 1.00 12.22  ? 441 TRP E NE1 1 
ATOM   14712 C  CE2 . TRP E 1 441 ? 203.099 290.310 251.541 1.00 11.90  ? 441 TRP E CE2 1 
ATOM   14713 C  CE3 . TRP E 1 441 ? 202.923 292.686 251.151 1.00 14.14  ? 441 TRP E CE3 1 
ATOM   14714 C  CZ2 . TRP E 1 441 ? 202.032 290.330 252.434 1.00 13.85  ? 441 TRP E CZ2 1 
ATOM   14715 C  CZ3 . TRP E 1 441 ? 201.866 292.704 252.039 1.00 12.06  ? 441 TRP E CZ3 1 
ATOM   14716 C  CH2 . TRP E 1 441 ? 201.430 291.534 252.668 1.00 14.63  ? 441 TRP E CH2 1 
ATOM   14717 N  N   . LYS E 1 442 ? 206.389 293.085 252.208 1.00 12.11  ? 442 LYS E N   1 
ATOM   14718 C  CA  . LYS E 1 442 ? 205.984 293.934 253.318 1.00 13.99  ? 442 LYS E CA  1 
ATOM   14719 C  C   . LYS E 1 442 ? 207.166 294.417 254.149 1.00 14.55  ? 442 LYS E C   1 
ATOM   14720 O  O   . LYS E 1 442 ? 206.965 294.933 255.253 1.00 15.23  ? 442 LYS E O   1 
ATOM   14721 C  CB  . LYS E 1 442 ? 204.983 293.195 254.210 1.00 16.54  ? 442 LYS E CB  1 
ATOM   14722 C  CG  . LYS E 1 442 ? 205.522 291.913 254.818 1.00 13.89  ? 442 LYS E CG  1 
ATOM   14723 C  CD  . LYS E 1 442 ? 206.194 292.169 256.155 1.00 14.69  ? 442 LYS E CD  1 
ATOM   14724 C  CE  . LYS E 1 442 ? 207.313 291.177 256.389 1.00 13.50  ? 442 LYS E CE  1 
ATOM   14725 N  NZ  . LYS E 1 442 ? 207.921 291.313 257.735 1.00 12.57  ? 442 LYS E NZ  1 
ATOM   14726 N  N   . ASP E 1 443 ? 208.387 294.273 253.646 1.00 12.61  ? 443 ASP E N   1 
ATOM   14727 C  CA  . ASP E 1 443 ? 209.585 294.611 254.396 1.00 15.45  ? 443 ASP E CA  1 
ATOM   14728 C  C   . ASP E 1 443 ? 210.161 295.943 253.931 1.00 17.28  ? 443 ASP E C   1 
ATOM   14729 O  O   . ASP E 1 443 ? 209.992 296.348 252.779 1.00 18.11  ? 443 ASP E O   1 
ATOM   14730 C  CB  . ASP E 1 443 ? 210.640 293.511 254.256 1.00 13.02  ? 443 ASP E CB  1 
ATOM   14731 C  CG  . ASP E 1 443 ? 210.502 292.434 255.312 1.00 22.94  ? 443 ASP E CG  1 
ATOM   14732 O  OD1 . ASP E 1 443 ? 210.401 292.781 256.507 1.00 31.77  ? 443 ASP E OD1 1 
ATOM   14733 O  OD2 . ASP E 1 443 ? 210.497 291.240 254.952 1.00 27.18  ? 443 ASP E OD2 1 
ATOM   14734 N  N   . VAL E 1 444 ? 210.850 296.621 254.847 1.00 18.78  ? 444 VAL E N   1 
ATOM   14735 C  CA  . VAL E 1 444 ? 211.542 297.864 254.526 1.00 19.31  ? 444 VAL E CA  1 
ATOM   14736 C  C   . VAL E 1 444 ? 212.862 297.528 253.846 1.00 18.41  ? 444 VAL E C   1 
ATOM   14737 O  O   . VAL E 1 444 ? 213.305 296.375 253.863 1.00 23.63  ? 444 VAL E O   1 
ATOM   14738 C  CB  . VAL E 1 444 ? 211.764 298.732 255.778 1.00 15.92  ? 444 VAL E CB  1 
ATOM   14739 C  CG1 . VAL E 1 444 ? 210.435 299.216 256.330 1.00 11.82  ? 444 VAL E CG1 1 
ATOM   14740 C  CG2 . VAL E 1 444 ? 212.536 297.964 256.834 1.00 18.56  ? 444 VAL E CG2 1 
ATOM   14741 N  N   . ALA E 1 445 ? 213.496 298.536 253.241 1.00 18.79  ? 445 ALA E N   1 
ATOM   14742 C  CA  . ALA E 1 445 ? 214.709 298.300 252.464 1.00 17.96  ? 445 ALA E CA  1 
ATOM   14743 C  C   . ALA E 1 445 ? 215.804 297.650 253.298 1.00 24.92  ? 445 ALA E C   1 
ATOM   14744 O  O   . ALA E 1 445 ? 216.652 296.932 252.757 1.00 27.44  ? 445 ALA E O   1 
ATOM   14745 C  CB  . ALA E 1 445 ? 215.210 299.613 251.868 1.00 12.70  ? 445 ALA E CB  1 
ATOM   14746 N  N   . ARG E 1 446 ? 215.804 297.886 254.610 1.00 25.63  ? 446 ARG E N   1 
ATOM   14747 C  CA  . ARG E 1 446 ? 216.824 297.294 255.466 1.00 18.96  ? 446 ARG E CA  1 
ATOM   14748 C  C   . ARG E 1 446 ? 216.756 295.773 255.440 1.00 20.96  ? 446 ARG E C   1 
ATOM   14749 O  O   . ARG E 1 446 ? 217.791 295.099 255.389 1.00 23.63  ? 446 ARG E O   1 
ATOM   14750 C  CB  . ARG E 1 446 ? 216.666 297.810 256.895 1.00 23.15  ? 446 ARG E CB  1 
ATOM   14751 C  CG  . ARG E 1 446 ? 217.830 297.484 257.801 1.00 27.39  ? 446 ARG E CG  1 
ATOM   14752 C  CD  . ARG E 1 446 ? 217.353 296.862 259.095 1.00 23.37  ? 446 ARG E CD  1 
ATOM   14753 N  NE  . ARG E 1 446 ? 218.470 296.400 259.908 1.00 30.25  ? 446 ARG E NE  1 
ATOM   14754 C  CZ  . ARG E 1 446 ? 218.398 295.411 260.787 1.00 29.09  ? 446 ARG E CZ  1 
ATOM   14755 N  NH1 . ARG E 1 446 ? 217.267 294.763 261.007 1.00 27.43  ? 446 ARG E NH1 1 
ATOM   14756 N  NH2 . ARG E 1 446 ? 219.490 295.062 261.460 1.00 32.04  ? 446 ARG E NH2 1 
ATOM   14757 N  N   . PHE E 1 447 ? 215.548 295.213 255.475 1.00 22.22  ? 447 PHE E N   1 
ATOM   14758 C  CA  . PHE E 1 447 ? 215.390 293.769 255.572 1.00 19.86  ? 447 PHE E CA  1 
ATOM   14759 C  C   . PHE E 1 447 ? 215.481 293.061 254.228 1.00 21.59  ? 447 PHE E C   1 
ATOM   14760 O  O   . PHE E 1 447 ? 215.569 291.830 254.205 1.00 21.30  ? 447 PHE E O   1 
ATOM   14761 C  CB  . PHE E 1 447 ? 214.061 293.431 256.246 1.00 15.79  ? 447 PHE E CB  1 
ATOM   14762 C  CG  . PHE E 1 447 ? 214.043 293.723 257.715 1.00 20.22  ? 447 PHE E CG  1 
ATOM   14763 C  CD1 . PHE E 1 447 ? 214.537 292.804 258.621 1.00 21.34  ? 447 PHE E CD1 1 
ATOM   14764 C  CD2 . PHE E 1 447 ? 213.537 294.919 258.189 1.00 23.25  ? 447 PHE E CD2 1 
ATOM   14765 C  CE1 . PHE E 1 447 ? 214.526 293.070 259.972 1.00 23.83  ? 447 PHE E CE1 1 
ATOM   14766 C  CE2 . PHE E 1 447 ? 213.523 295.191 259.541 1.00 21.88  ? 447 PHE E CE2 1 
ATOM   14767 C  CZ  . PHE E 1 447 ? 214.019 294.265 260.433 1.00 21.88  ? 447 PHE E CZ  1 
ATOM   14768 N  N   . ILE E 1 448 ? 215.465 293.798 253.113 1.00 21.51  ? 448 ILE E N   1 
ATOM   14769 C  CA  . ILE E 1 448 ? 215.716 293.192 251.811 1.00 19.37  ? 448 ILE E CA  1 
ATOM   14770 C  C   . ILE E 1 448 ? 217.194 293.203 251.455 1.00 21.79  ? 448 ILE E C   1 
ATOM   14771 O  O   . ILE E 1 448 ? 217.561 292.779 250.351 1.00 27.77  ? 448 ILE E O   1 
ATOM   14772 C  CB  . ILE E 1 448 ? 214.890 293.883 250.706 1.00 21.70  ? 448 ILE E CB  1 
ATOM   14773 C  CG1 . ILE E 1 448 ? 215.432 295.283 250.416 1.00 19.95  ? 448 ILE E CG1 1 
ATOM   14774 C  CG2 . ILE E 1 448 ? 213.427 293.949 251.103 1.00 18.83  ? 448 ILE E CG2 1 
ATOM   14775 C  CD1 . ILE E 1 448 ? 215.167 295.751 249.010 1.00 15.32  ? 448 ILE E CD1 1 
ATOM   14776 N  N   . ARG E 1 449 ? 218.053 293.674 252.354 1.00 24.74  ? 449 ARG E N   1 
ATOM   14777 C  CA  . ARG E 1 449 ? 219.490 293.547 252.165 1.00 20.39  ? 449 ARG E CA  1 
ATOM   14778 C  C   . ARG E 1 449 ? 219.900 292.083 252.249 1.00 26.36  ? 449 ARG E C   1 
ATOM   14779 O  O   . ARG E 1 449 ? 219.355 291.314 253.043 1.00 28.24  ? 449 ARG E O   1 
ATOM   14780 C  CB  . ARG E 1 449 ? 220.239 294.364 253.215 1.00 20.74  ? 449 ARG E CB  1 
ATOM   14781 C  CG  . ARG E 1 449 ? 220.632 295.752 252.759 1.00 25.96  ? 449 ARG E CG  1 
ATOM   14782 C  CD  . ARG E 1 449 ? 220.838 296.683 253.940 1.00 27.18  ? 449 ARG E CD  1 
ATOM   14783 N  NE  . ARG E 1 449 ? 220.245 297.992 253.701 1.00 33.70  ? 449 ARG E NE  1 
ATOM   14784 C  CZ  . ARG E 1 449 ? 220.004 298.892 254.644 1.00 41.32  ? 449 ARG E CZ  1 
ATOM   14785 N  NH1 . ARG E 1 449 ? 220.295 298.659 255.913 1.00 41.15  ? 449 ARG E NH1 1 
ATOM   14786 N  NH2 . ARG E 1 449 ? 219.456 300.055 254.304 1.00 37.75  ? 449 ARG E NH2 1 
ATOM   14787 N  N   . SER E 1 450 ? 220.877 291.701 251.427 1.00 24.37  ? 450 SER E N   1 
ATOM   14788 C  CA  . SER E 1 450 ? 221.275 290.303 251.339 1.00 20.23  ? 450 SER E CA  1 
ATOM   14789 C  C   . SER E 1 450 ? 221.992 289.804 252.585 1.00 26.02  ? 450 SER E C   1 
ATOM   14790 O  O   . SER E 1 450 ? 222.210 288.594 252.706 1.00 31.21  ? 450 SER E O   1 
ATOM   14791 C  CB  . SER E 1 450 ? 222.161 290.094 250.111 1.00 21.97  ? 450 SER E CB  1 
ATOM   14792 O  OG  . SER E 1 450 ? 221.418 290.277 248.920 1.00 25.12  ? 450 SER E OG  1 
ATOM   14793 N  N   . ALA E 1 451 ? 222.358 290.688 253.512 1.00 28.25  ? 451 ALA E N   1 
ATOM   14794 C  CA  . ALA E 1 451 ? 223.057 290.290 254.725 1.00 25.17  ? 451 ALA E CA  1 
ATOM   14795 C  C   . ALA E 1 451 ? 222.159 290.240 255.953 1.00 29.52  ? 451 ALA E C   1 
ATOM   14796 O  O   . ALA E 1 451 ? 222.577 289.701 256.982 1.00 36.69  ? 451 ALA E O   1 
ATOM   14797 C  CB  . ALA E 1 451 ? 224.230 291.239 254.997 1.00 27.43  ? 451 ALA E CB  1 
ATOM   14798 N  N   . THR E 1 452 ? 220.947 290.783 255.877 1.00 24.82  ? 452 THR E N   1 
ATOM   14799 C  CA  . THR E 1 452 ? 220.046 290.787 257.021 1.00 23.58  ? 452 THR E CA  1 
ATOM   14800 C  C   . THR E 1 452 ? 219.451 289.401 257.230 1.00 28.33  ? 452 THR E C   1 
ATOM   14801 O  O   . THR E 1 452 ? 218.939 288.785 256.291 1.00 32.39  ? 452 THR E O   1 
ATOM   14802 C  CB  . THR E 1 452 ? 218.932 291.815 256.825 1.00 25.44  ? 452 THR E CB  1 
ATOM   14803 O  OG1 . THR E 1 452 ? 219.488 293.029 256.305 1.00 29.63  ? 452 THR E OG1 1 
ATOM   14804 C  CG2 . THR E 1 452 ? 218.239 292.109 258.145 1.00 23.51  ? 452 THR E CG2 1 
ATOM   14805 N  N   . ARG E 1 453 ? 219.525 288.913 258.463 1.00 30.36  ? 453 ARG E N   1 
ATOM   14806 C  CA  . ARG E 1 453 ? 218.977 287.618 258.834 1.00 23.23  ? 453 ARG E CA  1 
ATOM   14807 C  C   . ARG E 1 453 ? 217.655 287.806 259.564 1.00 26.79  ? 453 ARG E C   1 
ATOM   14808 O  O   . ARG E 1 453 ? 217.535 288.676 260.432 1.00 32.14  ? 453 ARG E O   1 
ATOM   14809 C  CB  . ARG E 1 453 ? 219.949 286.850 259.733 1.00 25.54  ? 453 ARG E CB  1 
ATOM   14810 C  CG  . ARG E 1 453 ? 221.393 286.859 259.267 1.00 28.40  ? 453 ARG E CG  1 
ATOM   14811 C  CD  . ARG E 1 453 ? 222.335 286.433 260.385 1.00 30.84  ? 453 ARG E CD  1 
ATOM   14812 N  NE  . ARG E 1 453 ? 222.326 284.993 260.612 1.00 31.46  ? 453 ARG E NE  1 
ATOM   14813 C  CZ  . ARG E 1 453 ? 222.337 284.424 261.810 1.00 32.54  ? 453 ARG E CZ  1 
ATOM   14814 N  NH1 . ARG E 1 453 ? 222.346 285.145 262.918 1.00 28.89  ? 453 ARG E NH1 1 
ATOM   14815 N  NH2 . ARG E 1 453 ? 222.338 283.097 261.899 1.00 30.51  ? 453 ARG E NH2 1 
ATOM   14816 N  N   . SER E 1 454 ? 216.666 286.994 259.214 1.00 24.66  ? 454 SER E N   1 
ATOM   14817 C  CA  . SER E 1 454 ? 215.434 286.898 259.975 1.00 23.44  ? 454 SER E CA  1 
ATOM   14818 C  C   . SER E 1 454 ? 215.279 285.458 260.438 1.00 21.80  ? 454 SER E C   1 
ATOM   14819 O  O   . SER E 1 454 ? 216.108 284.600 260.142 1.00 22.42  ? 454 SER E O   1 
ATOM   14820 C  CB  . SER E 1 454 ? 214.236 287.351 259.138 1.00 22.37  ? 454 SER E CB  1 
ATOM   14821 O  OG  . SER E 1 454 ? 214.022 288.744 259.273 1.00 35.44  ? 454 SER E OG  1 
ATOM   14822 N  N   . HIS E 1 455 ? 214.194 285.177 261.149 1.00 21.45  ? 455 HIS E N   1 
ATOM   14823 C  CA  . HIS E 1 455 ? 213.959 283.810 261.578 1.00 20.68  ? 455 HIS E CA  1 
ATOM   14824 C  C   . HIS E 1 455 ? 212.468 283.591 261.756 1.00 21.61  ? 455 HIS E C   1 
ATOM   14825 O  O   . HIS E 1 455 ? 211.701 284.530 261.981 1.00 24.70  ? 455 HIS E O   1 
ATOM   14826 C  CB  . HIS E 1 455 ? 214.709 283.488 262.875 1.00 22.51  ? 455 HIS E CB  1 
ATOM   14827 C  CG  . HIS E 1 455 ? 214.707 284.607 263.866 1.00 27.27  ? 455 HIS E CG  1 
ATOM   14828 N  ND1 . HIS E 1 455 ? 213.860 284.637 264.951 1.00 27.35  ? 455 HIS E ND1 1 
ATOM   14829 C  CD2 . HIS E 1 455 ? 215.440 285.744 263.929 1.00 28.70  ? 455 HIS E CD2 1 
ATOM   14830 C  CE1 . HIS E 1 455 ? 214.076 285.740 265.645 1.00 33.18  ? 455 HIS E CE1 1 
ATOM   14831 N  NE2 . HIS E 1 455 ? 215.030 286.429 265.046 1.00 34.14  ? 455 HIS E NE2 1 
ATOM   14832 N  N   . GLU E 1 456 ? 212.069 282.329 261.644 1.00 20.92  ? 456 GLU E N   1 
ATOM   14833 C  CA  . GLU E 1 456 ? 210.687 281.954 261.898 1.00 18.32  ? 456 GLU E CA  1 
ATOM   14834 C  C   . GLU E 1 456 ? 210.655 280.543 262.460 1.00 20.49  ? 456 GLU E C   1 
ATOM   14835 O  O   . GLU E 1 456 ? 211.557 279.741 262.222 1.00 20.06  ? 456 GLU E O   1 
ATOM   14836 C  CB  . GLU E 1 456 ? 209.831 282.055 260.631 1.00 15.21  ? 456 GLU E CB  1 
ATOM   14837 C  CG  . GLU E 1 456 ? 208.346 281.862 260.876 1.00 17.00  ? 456 GLU E CG  1 
ATOM   14838 C  CD  . GLU E 1 456 ? 207.787 282.857 261.873 1.00 28.92  ? 456 GLU E CD  1 
ATOM   14839 O  OE1 . GLU E 1 456 ? 207.405 283.970 261.457 1.00 34.38  ? 456 GLU E OE1 1 
ATOM   14840 O  OE2 . GLU E 1 456 ? 207.731 282.527 263.075 1.00 28.23  ? 456 GLU E OE2 1 
ATOM   14841 N  N   . TYR E 1 457 ? 209.602 280.247 263.213 1.00 24.57  ? 457 TYR E N   1 
ATOM   14842 C  CA  . TYR E 1 457 ? 209.437 278.909 263.758 1.00 16.15  ? 457 TYR E CA  1 
ATOM   14843 C  C   . TYR E 1 457 ? 209.107 277.920 262.647 1.00 17.68  ? 457 TYR E C   1 
ATOM   14844 O  O   . TYR E 1 457 ? 208.371 278.235 261.709 1.00 19.16  ? 457 TYR E O   1 
ATOM   14845 C  CB  . TYR E 1 457 ? 208.351 278.905 264.829 1.00 19.38  ? 457 TYR E CB  1 
ATOM   14846 C  CG  . TYR E 1 457 ? 208.755 279.634 266.088 1.00 19.92  ? 457 TYR E CG  1 
ATOM   14847 C  CD1 . TYR E 1 457 ? 209.651 279.067 266.982 1.00 18.78  ? 457 TYR E CD1 1 
ATOM   14848 C  CD2 . TYR E 1 457 ? 208.250 280.893 266.378 1.00 20.91  ? 457 TYR E CD2 1 
ATOM   14849 C  CE1 . TYR E 1 457 ? 210.026 279.730 268.131 1.00 22.17  ? 457 TYR E CE1 1 
ATOM   14850 C  CE2 . TYR E 1 457 ? 208.619 281.563 267.523 1.00 18.96  ? 457 TYR E CE2 1 
ATOM   14851 C  CZ  . TYR E 1 457 ? 209.507 280.978 268.397 1.00 26.42  ? 457 TYR E CZ  1 
ATOM   14852 O  OH  . TYR E 1 457 ? 209.877 281.645 269.541 1.00 31.17  ? 457 TYR E OH  1 
ATOM   14853 N  N   . GLN E 1 458 ? 209.657 276.711 262.765 1.00 17.86  ? 458 GLN E N   1 
ATOM   14854 C  CA  . GLN E 1 458 ? 209.612 275.749 261.669 1.00 16.78  ? 458 GLN E CA  1 
ATOM   14855 C  C   . GLN E 1 458 ? 208.197 275.309 261.319 1.00 18.29  ? 458 GLN E C   1 
ATOM   14856 O  O   . GLN E 1 458 ? 207.971 274.832 260.203 1.00 22.16  ? 458 GLN E O   1 
ATOM   14857 C  CB  . GLN E 1 458 ? 210.462 274.528 262.018 1.00 16.44  ? 458 GLN E CB  1 
ATOM   14858 C  CG  . GLN E 1 458 ? 209.996 273.782 263.252 1.00 17.85  ? 458 GLN E CG  1 
ATOM   14859 C  CD  . GLN E 1 458 ? 210.807 272.535 263.514 1.00 20.81  ? 458 GLN E CD  1 
ATOM   14860 O  OE1 . GLN E 1 458 ? 212.024 272.596 263.672 1.00 24.55  ? 458 GLN E OE1 1 
ATOM   14861 N  NE2 . GLN E 1 458 ? 210.137 271.393 263.558 1.00 26.30  ? 458 GLN E NE2 1 
ATOM   14862 N  N   . ASN E 1 459 ? 207.243 275.445 262.236 1.00 16.31  ? 459 ASN E N   1 
ATOM   14863 C  CA  . ASN E 1 459 ? 205.873 275.016 261.992 1.00 16.91  ? 459 ASN E CA  1 
ATOM   14864 C  C   . ASN E 1 459 ? 204.947 276.174 261.643 1.00 20.56  ? 459 ASN E C   1 
ATOM   14865 O  O   . ASN E 1 459 ? 203.726 275.991 261.618 1.00 25.97  ? 459 ASN E O   1 
ATOM   14866 C  CB  . ASN E 1 459 ? 205.332 274.254 263.204 1.00 17.05  ? 459 ASN E CB  1 
ATOM   14867 C  CG  . ASN E 1 459 ? 205.254 275.112 264.451 1.00 19.14  ? 459 ASN E CG  1 
ATOM   14868 O  OD1 . ASN E 1 459 ? 205.909 276.148 264.551 1.00 21.82  ? 459 ASN E OD1 1 
ATOM   14869 N  ND2 . ASN E 1 459 ? 204.451 274.679 265.415 1.00 19.15  ? 459 ASN E ND2 1 
ATOM   14870 N  N   . VAL E 1 460 ? 205.496 277.352 261.365 1.00 16.50  ? 460 VAL E N   1 
ATOM   14871 C  CA  . VAL E 1 460 ? 204.714 278.554 261.105 1.00 15.53  ? 460 VAL E CA  1 
ATOM   14872 C  C   . VAL E 1 460 ? 204.820 278.901 259.627 1.00 19.03  ? 460 VAL E C   1 
ATOM   14873 O  O   . VAL E 1 460 ? 205.925 278.970 259.075 1.00 25.25  ? 460 VAL E O   1 
ATOM   14874 C  CB  . VAL E 1 460 ? 205.185 279.732 261.975 1.00 20.23  ? 460 VAL E CB  1 
ATOM   14875 C  CG1 . VAL E 1 460 ? 204.575 281.031 261.481 1.00 16.33  ? 460 VAL E CG1 1 
ATOM   14876 C  CG2 . VAL E 1 460 ? 204.832 279.488 263.429 1.00 19.00  ? 460 VAL E CG2 1 
ATOM   14877 N  N   . GLY E 1 461 ? 203.675 279.110 258.990 1.00 19.58  ? 461 GLY E N   1 
ATOM   14878 C  CA  . GLY E 1 461 ? 203.610 279.592 257.618 1.00 16.27  ? 461 GLY E CA  1 
ATOM   14879 C  C   . GLY E 1 461 ? 203.117 281.028 257.601 1.00 18.42  ? 461 GLY E C   1 
ATOM   14880 O  O   . GLY E 1 461 ? 202.222 281.392 258.367 1.00 21.27  ? 461 GLY E O   1 
ATOM   14881 N  N   . ARG E 1 462 ? 203.708 281.838 256.727 1.00 18.81  ? 462 ARG E N   1 
ATOM   14882 C  CA  . ARG E 1 462 ? 203.403 283.259 256.653 1.00 18.55  ? 462 ARG E CA  1 
ATOM   14883 C  C   . ARG E 1 462 ? 203.046 283.638 255.224 1.00 16.60  ? 462 ARG E C   1 
ATOM   14884 O  O   . ARG E 1 462 ? 203.432 282.967 254.265 1.00 19.90  ? 462 ARG E O   1 
ATOM   14885 C  CB  . ARG E 1 462 ? 204.581 284.112 257.132 1.00 17.54  ? 462 ARG E CB  1 
ATOM   14886 C  CG  . ARG E 1 462 ? 204.919 283.928 258.590 1.00 17.18  ? 462 ARG E CG  1 
ATOM   14887 C  CD  . ARG E 1 462 ? 204.051 284.791 259.469 1.00 21.56  ? 462 ARG E CD  1 
ATOM   14888 N  NE  . ARG E 1 462 ? 204.437 284.674 260.868 1.00 25.47  ? 462 ARG E NE  1 
ATOM   14889 C  CZ  . ARG E 1 462 ? 203.872 285.346 261.858 1.00 24.46  ? 462 ARG E CZ  1 
ATOM   14890 N  NH1 . ARG E 1 462 ? 202.890 286.204 261.638 1.00 29.31  ? 462 ARG E NH1 1 
ATOM   14891 N  NH2 . ARG E 1 462 ? 204.302 285.154 263.101 1.00 29.24  ? 462 ARG E NH2 1 
ATOM   14892 N  N   . SER E 1 463 ? 202.306 284.737 255.094 1.00 17.56  ? 463 SER E N   1 
ATOM   14893 C  CA  . SER E 1 463 ? 201.931 285.257 253.786 1.00 12.93  ? 463 SER E CA  1 
ATOM   14894 C  C   . SER E 1 463 ? 203.060 286.022 253.112 1.00 12.88  ? 463 SER E C   1 
ATOM   14895 O  O   . SER E 1 463 ? 202.861 286.541 252.010 1.00 16.90  ? 463 SER E O   1 
ATOM   14896 C  CB  . SER E 1 463 ? 200.698 286.157 253.906 1.00 11.74  ? 463 SER E CB  1 
ATOM   14897 O  OG  . SER E 1 463 ? 200.837 287.090 254.960 1.00 15.28  ? 463 SER E OG  1 
ATOM   14898 N  N   . TYR E 1 464 ? 204.234 286.098 253.742 1.00 14.70  ? 464 TYR E N   1 
ATOM   14899 C  CA  . TYR E 1 464 ? 205.383 286.795 253.180 1.00 12.38  ? 464 TYR E CA  1 
ATOM   14900 C  C   . TYR E 1 464 ? 206.627 285.915 253.152 1.00 13.99  ? 464 TYR E C   1 
ATOM   14901 O  O   . TYR E 1 464 ? 207.738 286.430 253.003 1.00 17.29  ? 464 TYR E O   1 
ATOM   14902 C  CB  . TYR E 1 464 ? 205.665 288.085 253.955 1.00 12.74  ? 464 TYR E CB  1 
ATOM   14903 C  CG  . TYR E 1 464 ? 205.724 287.903 255.453 1.00 12.81  ? 464 TYR E CG  1 
ATOM   14904 C  CD1 . TYR E 1 464 ? 206.864 287.409 256.071 1.00 11.78  ? 464 TYR E CD1 1 
ATOM   14905 C  CD2 . TYR E 1 464 ? 204.635 288.224 256.250 1.00 14.70  ? 464 TYR E CD2 1 
ATOM   14906 C  CE1 . TYR E 1 464 ? 206.917 287.240 257.438 1.00 15.24  ? 464 TYR E CE1 1 
ATOM   14907 C  CE2 . TYR E 1 464 ? 204.679 288.061 257.617 1.00 15.28  ? 464 TYR E CE2 1 
ATOM   14908 C  CZ  . TYR E 1 464 ? 205.822 287.569 258.205 1.00 16.46  ? 464 TYR E CZ  1 
ATOM   14909 O  OH  . TYR E 1 464 ? 205.869 287.404 259.568 1.00 22.48  ? 464 TYR E OH  1 
ATOM   14910 N  N   . ILE E 1 465 ? 206.469 284.601 253.289 1.00 13.39  ? 465 ILE E N   1 
ATOM   14911 C  CA  . ILE E 1 465 ? 207.590 283.669 253.266 1.00 14.85  ? 465 ILE E CA  1 
ATOM   14912 C  C   . ILE E 1 465 ? 207.283 282.569 252.261 1.00 15.60  ? 465 ILE E C   1 
ATOM   14913 O  O   . ILE E 1 465 ? 206.272 281.869 252.390 1.00 19.00  ? 465 ILE E O   1 
ATOM   14914 C  CB  . ILE E 1 465 ? 207.873 283.067 254.653 1.00 16.71  ? 465 ILE E CB  1 
ATOM   14915 C  CG1 . ILE E 1 465 ? 208.110 284.174 255.680 1.00 16.18  ? 465 ILE E CG1 1 
ATOM   14916 C  CG2 . ILE E 1 465 ? 209.070 282.133 254.594 1.00 10.03  ? 465 ILE E CG2 1 
ATOM   14917 C  CD1 . ILE E 1 465 ? 208.417 283.662 257.067 1.00 13.66  ? 465 ILE E CD1 1 
ATOM   14918 N  N   . GLY E 1 466 ? 208.152 282.418 251.267 1.00 13.67  ? 466 GLY E N   1 
ATOM   14919 C  CA  . GLY E 1 466 ? 208.105 281.303 250.345 1.00 14.85  ? 466 GLY E CA  1 
ATOM   14920 C  C   . GLY E 1 466 ? 209.396 280.516 250.407 1.00 13.00  ? 466 GLY E C   1 
ATOM   14921 O  O   . GLY E 1 466 ? 209.968 280.357 251.489 1.00 19.23  ? 466 GLY E O   1 
ATOM   14922 N  N   . PHE E 1 467 ? 209.877 280.023 249.270 1.00 16.39  ? 467 PHE E N   1 
ATOM   14923 C  CA  . PHE E 1 467 ? 211.152 279.321 249.266 1.00 13.21  ? 467 PHE E CA  1 
ATOM   14924 C  C   . PHE E 1 467 ? 211.503 278.930 247.838 1.00 13.50  ? 467 PHE E C   1 
ATOM   14925 O  O   . PHE E 1 467 ? 210.642 278.891 246.956 1.00 18.33  ? 467 PHE E O   1 
ATOM   14926 C  CB  . PHE E 1 467 ? 211.119 278.075 250.160 1.00 13.93  ? 467 PHE E CB  1 
ATOM   14927 C  CG  . PHE E 1 467 ? 210.309 276.942 249.596 1.00 14.92  ? 467 PHE E CG  1 
ATOM   14928 C  CD1 . PHE E 1 467 ? 208.925 276.972 249.632 1.00 11.47  ? 467 PHE E CD1 1 
ATOM   14929 C  CD2 . PHE E 1 467 ? 210.935 275.844 249.032 1.00 16.12  ? 467 PHE E CD2 1 
ATOM   14930 C  CE1 . PHE E 1 467 ? 208.182 275.933 249.112 1.00 12.05  ? 467 PHE E CE1 1 
ATOM   14931 C  CE2 . PHE E 1 467 ? 210.197 274.802 248.512 1.00 14.09  ? 467 PHE E CE2 1 
ATOM   14932 C  CZ  . PHE E 1 467 ? 208.819 274.845 248.552 1.00 14.81  ? 467 PHE E CZ  1 
ATOM   14933 N  N   . ARG E 1 468 ? 212.786 278.654 247.625 1.00 15.89  ? 468 ARG E N   1 
ATOM   14934 C  CA  . ARG E 1 468 ? 213.280 277.985 246.432 1.00 15.87  ? 468 ARG E CA  1 
ATOM   14935 C  C   . ARG E 1 468 ? 214.248 276.894 246.866 1.00 15.92  ? 468 ARG E C   1 
ATOM   14936 O  O   . ARG E 1 468 ? 214.713 276.867 248.007 1.00 17.30  ? 468 ARG E O   1 
ATOM   14937 C  CB  . ARG E 1 468 ? 213.958 278.962 245.461 1.00 16.38  ? 468 ARG E CB  1 
ATOM   14938 C  CG  . ARG E 1 468 ? 215.183 279.665 246.015 1.00 14.52  ? 468 ARG E CG  1 
ATOM   14939 C  CD  . ARG E 1 468 ? 215.676 280.732 245.052 1.00 15.97  ? 468 ARG E CD  1 
ATOM   14940 N  NE  . ARG E 1 468 ? 215.006 282.007 245.274 1.00 20.06  ? 468 ARG E NE  1 
ATOM   14941 C  CZ  . ARG E 1 468 ? 214.821 282.931 244.342 1.00 16.34  ? 468 ARG E CZ  1 
ATOM   14942 N  NH1 . ARG E 1 468 ? 215.257 282.762 243.106 1.00 13.61  ? 468 ARG E NH1 1 
ATOM   14943 N  NH2 . ARG E 1 468 ? 214.176 284.050 244.657 1.00 14.59  ? 468 ARG E NH2 1 
ATOM   14944 N  N   . CYS E 1 469 ? 214.549 275.982 245.949 1.00 17.70  ? 469 CYS E N   1 
ATOM   14945 C  CA  . CYS E 1 469 ? 215.380 274.828 246.250 1.00 17.32  ? 469 CYS E CA  1 
ATOM   14946 C  C   . CYS E 1 469 ? 216.738 274.943 245.572 1.00 16.61  ? 469 CYS E C   1 
ATOM   14947 O  O   . CYS E 1 469 ? 216.918 275.686 244.604 1.00 21.63  ? 469 CYS E O   1 
ATOM   14948 C  CB  . CYS E 1 469 ? 214.694 273.529 245.814 1.00 20.83  ? 469 CYS E CB  1 
ATOM   14949 S  SG  . CYS E 1 469 ? 212.902 273.523 246.024 1.00 42.21  ? 469 CYS E SG  1 
ATOM   14950 N  N   . VAL E 1 470 ? 217.700 274.193 246.107 1.00 15.48  ? 470 VAL E N   1 
ATOM   14951 C  CA  . VAL E 1 470 ? 219.027 274.068 245.525 1.00 16.53  ? 470 VAL E CA  1 
ATOM   14952 C  C   . VAL E 1 470 ? 219.353 272.587 245.388 1.00 18.56  ? 470 VAL E C   1 
ATOM   14953 O  O   . VAL E 1 470 ? 218.646 271.717 245.897 1.00 19.96  ? 470 VAL E O   1 
ATOM   14954 C  CB  . VAL E 1 470 ? 220.114 274.784 246.357 1.00 18.06  ? 470 VAL E CB  1 
ATOM   14955 C  CG1 . VAL E 1 470 ? 219.853 276.280 246.403 1.00 16.89  ? 470 VAL E CG1 1 
ATOM   14956 C  CG2 . VAL E 1 470 ? 220.187 274.198 247.758 1.00 16.68  ? 470 VAL E CG2 1 
ATOM   14957 N  N   . ARG E 1 471 ? 220.444 272.313 244.682 1.00 23.56  ? 471 ARG E N   1 
ATOM   14958 C  CA  . ARG E 1 471 ? 220.908 270.945 244.481 1.00 24.62  ? 471 ARG E CA  1 
ATOM   14959 C  C   . ARG E 1 471 ? 222.411 270.972 244.268 1.00 25.36  ? 471 ARG E C   1 
ATOM   14960 O  O   . ARG E 1 471 ? 222.888 271.622 243.336 1.00 27.88  ? 471 ARG E O   1 
ATOM   14961 C  CB  . ARG E 1 471 ? 220.209 270.292 243.287 1.00 27.47  ? 471 ARG E CB  1 
ATOM   14962 C  CG  . ARG E 1 471 ? 220.417 268.791 243.198 1.00 33.76  ? 471 ARG E CG  1 
ATOM   14963 C  CD  . ARG E 1 471 ? 219.255 268.114 242.499 1.00 39.16  ? 471 ARG E CD  1 
ATOM   14964 N  NE  . ARG E 1 471 ? 219.378 268.180 241.048 1.00 49.22  ? 471 ARG E NE  1 
ATOM   14965 C  CZ  . ARG E 1 471 ? 220.270 267.502 240.340 1.00 57.66  ? 471 ARG E CZ  1 
ATOM   14966 N  NH1 . ARG E 1 471 ? 221.135 266.686 240.918 1.00 58.19  ? 471 ARG E NH1 1 
ATOM   14967 N  NH2 . ARG E 1 471 ? 220.293 267.644 239.018 1.00 63.67  ? 471 ARG E NH2 1 
ATOM   14968 N  N   . THR E 1 472 ? 223.156 270.278 245.122 1.00 31.61  ? 472 THR E N   1 
ATOM   14969 C  CA  . THR E 1 472 ? 224.599 270.216 244.943 1.00 29.48  ? 472 THR E CA  1 
ATOM   14970 C  C   . THR E 1 472 ? 224.923 269.651 243.567 1.00 35.83  ? 472 THR E C   1 
ATOM   14971 O  O   . THR E 1 472 ? 224.396 268.609 243.168 1.00 41.17  ? 472 THR E O   1 
ATOM   14972 C  CB  . THR E 1 472 ? 225.241 269.362 246.034 1.00 32.48  ? 472 THR E CB  1 
ATOM   14973 O  OG1 . THR E 1 472 ? 225.332 270.121 247.245 1.00 33.66  ? 472 THR E OG1 1 
ATOM   14974 C  CG2 . THR E 1 472 ? 226.634 268.927 245.615 1.00 27.80  ? 472 THR E CG2 1 
ATOM   14975 N  N   . SER E 1 473 ? 225.791 270.344 242.841 1.00 37.21  ? 473 SER E N   1 
ATOM   14976 C  CA  . SER E 1 473 ? 226.136 269.981 241.475 1.00 39.57  ? 473 SER E CA  1 
ATOM   14977 C  C   . SER E 1 473 ? 227.487 269.280 241.452 1.00 48.92  ? 473 SER E C   1 
ATOM   14978 O  O   . SER E 1 473 ? 228.434 269.725 242.109 1.00 48.47  ? 473 SER E O   1 
ATOM   14979 C  CB  . SER E 1 473 ? 226.161 271.218 240.576 1.00 36.49  ? 473 SER E CB  1 
ATOM   14980 O  OG  . SER E 1 473 ? 227.267 272.046 240.878 1.00 39.70  ? 473 SER E OG  1 
ATOM   14981 N  N   . ILE E 1 474 ? 227.570 268.185 240.699 1.00 54.50  ? 474 ILE E N   1 
ATOM   14982 C  CA  . ILE E 1 474 ? 228.821 267.441 240.540 1.00 59.44  ? 474 ILE E CA  1 
ATOM   14983 C  C   . ILE E 1 474 ? 229.527 268.055 239.335 1.00 55.74  ? 474 ILE E C   1 
ATOM   14984 O  O   . ILE E 1 474 ? 229.289 267.682 238.186 1.00 52.53  ? 474 ILE E O   1 
ATOM   14985 C  CB  . ILE E 1 474 ? 228.583 265.942 240.376 1.00 64.00  ? 474 ILE E CB  1 
ATOM   14986 C  CG1 . ILE E 1 474 ? 227.129 265.583 240.698 1.00 60.63  ? 474 ILE E CG1 1 
ATOM   14987 C  CG2 . ILE E 1 474 ? 229.533 265.153 241.270 1.00 58.17  ? 474 ILE E CG2 1 
ATOM   14988 C  CD1 . ILE E 1 474 ? 226.770 265.697 242.166 1.00 54.24  ? 474 ILE E CD1 1 
ATOM   14989 N  N   . ALA E 1 475 ? 230.409 269.013 239.605 1.00 56.31  ? 475 ALA E N   1 
ATOM   14990 C  CA  . ALA E 1 475 ? 231.105 269.756 238.567 1.00 53.18  ? 475 ALA E CA  1 
ATOM   14991 C  C   . ALA E 1 475 ? 232.604 269.706 238.820 1.00 53.63  ? 475 ALA E C   1 
ATOM   14992 O  O   . ALA E 1 475 ? 233.056 269.671 239.967 1.00 55.05  ? 475 ALA E O   1 
ATOM   14993 C  CB  . ALA E 1 475 ? 230.632 271.215 238.509 1.00 45.83  ? 475 ALA E CB  1 
ATOM   14994 N  N   . PHE E 1 476 ? 233.372 269.705 237.736 1.00 55.55  ? 476 PHE E N   1 
ATOM   14995 C  CA  . PHE E 1 476 ? 234.823 269.611 237.833 1.00 54.54  ? 476 PHE E CA  1 
ATOM   14996 C  C   . PHE E 1 476 ? 235.511 270.742 237.076 1.00 54.48  ? 476 PHE E C   1 
ATOM   14997 O  O   . PHE E 1 476 ? 236.266 271.522 237.659 1.00 51.92  ? 476 PHE E O   1 
ATOM   14998 C  CB  . PHE E 1 476 ? 235.301 268.255 237.311 1.00 47.71  ? 476 PHE E CB  1 
ATOM   14999 C  CG  . PHE E 1 476 ? 234.462 267.101 237.777 1.00 45.84  ? 476 PHE E CG  1 
ATOM   15000 C  CD1 . PHE E 1 476 ? 234.718 266.487 238.991 1.00 41.26  ? 476 PHE E CD1 1 
ATOM   15001 C  CD2 . PHE E 1 476 ? 233.412 266.635 237.005 1.00 45.28  ? 476 PHE E CD2 1 
ATOM   15002 C  CE1 . PHE E 1 476 ? 233.946 265.431 239.423 1.00 40.83  ? 476 PHE E CE1 1 
ATOM   15003 C  CE2 . PHE E 1 476 ? 232.637 265.578 237.434 1.00 46.15  ? 476 PHE E CE2 1 
ATOM   15004 C  CZ  . PHE E 1 476 ? 232.904 264.976 238.644 1.00 46.42  ? 476 PHE E CZ  1 
ATOM   15005 N  N   . THR F 2 49  ? 217.171 267.400 281.809 1.00 48.26  ? 47  THR F N   1 
ATOM   15006 C  CA  . THR F 2 49  ? 216.253 268.385 281.251 1.00 54.94  ? 47  THR F CA  1 
ATOM   15007 C  C   . THR F 2 49  ? 216.479 268.552 279.751 1.00 55.58  ? 47  THR F C   1 
ATOM   15008 O  O   . THR F 2 49  ? 215.527 268.646 278.977 1.00 54.76  ? 47  THR F O   1 
ATOM   15009 C  CB  . THR F 2 49  ? 216.412 269.740 281.966 1.00 30.00  ? 47  THR F CB  1 
ATOM   15010 O  OG1 . THR F 2 49  ? 217.759 270.202 281.826 1.00 30.00  ? 47  THR F OG1 1 
ATOM   15011 C  CG2 . THR F 2 49  ? 216.253 269.572 283.469 1.00 30.00  ? 47  THR F CG2 1 
ATOM   15012 N  N   . LEU F 2 50  ? 217.747 268.593 279.351 1.00 48.31  ? 48  LEU F N   1 
ATOM   15013 C  CA  . LEU F 2 50  ? 218.085 268.701 277.939 1.00 38.12  ? 48  LEU F CA  1 
ATOM   15014 C  C   . LEU F 2 50  ? 217.818 267.385 277.220 1.00 41.71  ? 48  LEU F C   1 
ATOM   15015 O  O   . LEU F 2 50  ? 218.036 266.302 277.770 1.00 44.40  ? 48  LEU F O   1 
ATOM   15016 C  CB  . LEU F 2 50  ? 219.550 269.098 277.773 1.00 37.23  ? 48  LEU F CB  1 
ATOM   15017 C  CG  . LEU F 2 50  ? 219.820 270.471 277.157 1.00 43.44  ? 48  LEU F CG  1 
ATOM   15018 C  CD1 . LEU F 2 50  ? 219.266 271.574 278.042 1.00 44.29  ? 48  LEU F CD1 1 
ATOM   15019 C  CD2 . LEU F 2 50  ? 221.306 270.669 276.913 1.00 38.39  ? 48  LEU F CD2 1 
ATOM   15020 N  N   . SER F 2 51  ? 217.342 267.485 275.983 1.00 39.43  ? 49  SER F N   1 
ATOM   15021 C  CA  . SER F 2 51  ? 217.120 266.307 275.163 1.00 31.50  ? 49  SER F CA  1 
ATOM   15022 C  C   . SER F 2 51  ? 218.437 265.820 274.563 1.00 33.54  ? 49  SER F C   1 
ATOM   15023 O  O   . SER F 2 51  ? 219.464 266.500 274.610 1.00 35.81  ? 49  SER F O   1 
ATOM   15024 C  CB  . SER F 2 51  ? 216.108 266.607 274.059 1.00 33.83  ? 49  SER F CB  1 
ATOM   15025 O  OG  . SER F 2 51  ? 216.606 267.576 273.154 1.00 36.07  ? 49  SER F OG  1 
ATOM   15026 N  N   . ASN F 2 52  ? 218.398 264.614 273.992 1.00 31.71  ? 50  ASN F N   1 
ATOM   15027 C  CA  . ASN F 2 52  ? 219.591 264.061 273.360 1.00 31.28  ? 50  ASN F CA  1 
ATOM   15028 C  C   . ASN F 2 52  ? 220.011 264.894 272.156 1.00 32.23  ? 50  ASN F C   1 
ATOM   15029 O  O   . ASN F 2 52  ? 221.207 265.119 271.930 1.00 34.28  ? 50  ASN F O   1 
ATOM   15030 C  CB  . ASN F 2 52  ? 219.342 262.609 272.953 1.00 32.13  ? 50  ASN F CB  1 
ATOM   15031 C  CG  . ASN F 2 52  ? 220.624 261.853 272.679 1.00 33.22  ? 50  ASN F CG  1 
ATOM   15032 O  OD1 . ASN F 2 52  ? 220.914 261.493 271.540 1.00 36.48  ? 50  ASN F OD1 1 
ATOM   15033 N  ND2 . ASN F 2 52  ? 221.403 261.611 273.725 1.00 37.71  ? 50  ASN F ND2 1 
ATOM   15034 N  N   . ARG F 2 53  ? 219.039 265.364 271.372 1.00 32.86  ? 51  ARG F N   1 
ATOM   15035 C  CA  . ARG F 2 53  ? 219.347 266.244 270.250 1.00 32.51  ? 51  ARG F CA  1 
ATOM   15036 C  C   . ARG F 2 53  ? 220.064 267.501 270.726 1.00 31.06  ? 51  ARG F C   1 
ATOM   15037 O  O   . ARG F 2 53  ? 221.067 267.921 270.137 1.00 32.32  ? 51  ARG F O   1 
ATOM   15038 C  CB  . ARG F 2 53  ? 218.060 266.615 269.512 1.00 27.83  ? 51  ARG F CB  1 
ATOM   15039 C  CG  . ARG F 2 53  ? 217.356 265.457 268.836 1.00 27.28  ? 51  ARG F CG  1 
ATOM   15040 C  CD  . ARG F 2 53  ? 218.050 265.060 267.550 1.00 25.22  ? 51  ARG F CD  1 
ATOM   15041 N  NE  . ARG F 2 53  ? 217.117 264.469 266.599 1.00 25.93  ? 51  ARG F NE  1 
ATOM   15042 C  CZ  . ARG F 2 53  ? 217.476 263.749 265.546 1.00 26.74  ? 51  ARG F CZ  1 
ATOM   15043 N  NH1 . ARG F 2 53  ? 218.748 263.519 265.268 1.00 23.87  ? 51  ARG F NH1 1 
ATOM   15044 N  NH2 . ARG F 2 53  ? 216.536 263.254 264.748 1.00 27.46  ? 51  ARG F NH2 1 
ATOM   15045 N  N   . ALA F 2 54  ? 219.553 268.118 271.794 1.00 30.42  ? 52  ALA F N   1 
ATOM   15046 C  CA  . ALA F 2 54  ? 220.155 269.345 272.303 1.00 29.23  ? 52  ALA F CA  1 
ATOM   15047 C  C   . ALA F 2 54  ? 221.562 269.095 272.826 1.00 30.13  ? 52  ALA F C   1 
ATOM   15048 O  O   . ALA F 2 54  ? 222.463 269.916 272.621 1.00 34.15  ? 52  ALA F O   1 
ATOM   15049 C  CB  . ALA F 2 54  ? 219.273 269.947 273.395 1.00 30.59  ? 52  ALA F CB  1 
ATOM   15050 N  N   . GLN F 2 55  ? 221.769 267.971 273.514 1.00 33.80  ? 53  GLN F N   1 
ATOM   15051 C  CA  . GLN F 2 55  ? 223.104 267.649 274.007 1.00 32.62  ? 53  GLN F CA  1 
ATOM   15052 C  C   . GLN F 2 55  ? 224.078 267.439 272.856 1.00 33.25  ? 53  GLN F C   1 
ATOM   15053 O  O   . GLN F 2 55  ? 225.214 267.927 272.897 1.00 38.96  ? 53  GLN F O   1 
ATOM   15054 C  CB  . GLN F 2 55  ? 223.046 266.410 274.899 1.00 36.51  ? 53  GLN F CB  1 
ATOM   15055 C  CG  . GLN F 2 55  ? 222.341 266.640 276.224 1.00 34.87  ? 53  GLN F CG  1 
ATOM   15056 C  CD  . GLN F 2 55  ? 221.856 265.354 276.859 1.00 39.45  ? 53  GLN F CD  1 
ATOM   15057 O  OE1 . GLN F 2 55  ? 222.215 264.260 276.426 1.00 42.10  ? 53  GLN F OE1 1 
ATOM   15058 N  NE2 . GLN F 2 55  ? 221.036 265.479 277.895 1.00 37.55  ? 53  GLN F NE2 1 
ATOM   15059 N  N   . GLU F 2 56  ? 223.652 266.717 271.818 1.00 32.77  ? 54  GLU F N   1 
ATOM   15060 C  CA  . GLU F 2 56  ? 224.514 266.518 270.658 1.00 34.71  ? 54  GLU F CA  1 
ATOM   15061 C  C   . GLU F 2 56  ? 224.855 267.849 269.999 1.00 36.19  ? 54  GLU F C   1 
ATOM   15062 O  O   . GLU F 2 56  ? 226.017 268.115 269.667 1.00 41.72  ? 54  GLU F O   1 
ATOM   15063 C  CB  . GLU F 2 56  ? 223.835 265.576 269.663 1.00 38.27  ? 54  GLU F CB  1 
ATOM   15064 C  CG  . GLU F 2 56  ? 224.776 264.602 268.973 1.00 51.44  ? 54  GLU F CG  1 
ATOM   15065 C  CD  . GLU F 2 56  ? 225.378 265.167 267.701 1.00 59.85  ? 54  GLU F CD  1 
ATOM   15066 O  OE1 . GLU F 2 56  ? 224.615 265.428 266.747 1.00 56.75  ? 54  GLU F OE1 1 
ATOM   15067 O  OE2 . GLU F 2 56  ? 226.612 265.348 267.652 1.00 66.58  ? 54  GLU F OE2 1 
ATOM   15068 N  N   . PHE F 2 57  ? 223.853 268.712 269.824 1.00 34.86  ? 55  PHE F N   1 
ATOM   15069 C  CA  . PHE F 2 57  ? 224.087 270.013 269.205 1.00 33.37  ? 55  PHE F CA  1 
ATOM   15070 C  C   . PHE F 2 57  ? 225.072 270.841 270.021 1.00 36.25  ? 55  PHE F C   1 
ATOM   15071 O  O   . PHE F 2 57  ? 226.020 271.421 269.476 1.00 39.47  ? 55  PHE F O   1 
ATOM   15072 C  CB  . PHE F 2 57  ? 222.757 270.750 269.047 1.00 33.22  ? 55  PHE F CB  1 
ATOM   15073 C  CG  . PHE F 2 57  ? 222.822 271.937 268.133 1.00 33.75  ? 55  PHE F CG  1 
ATOM   15074 C  CD1 . PHE F 2 57  ? 223.342 271.818 266.858 1.00 35.70  ? 55  PHE F CD1 1 
ATOM   15075 C  CD2 . PHE F 2 57  ? 222.350 273.169 268.547 1.00 31.57  ? 55  PHE F CD2 1 
ATOM   15076 C  CE1 . PHE F 2 57  ? 223.396 272.908 266.014 1.00 36.07  ? 55  PHE F CE1 1 
ATOM   15077 C  CE2 . PHE F 2 57  ? 222.402 274.262 267.708 1.00 31.18  ? 55  PHE F CE2 1 
ATOM   15078 C  CZ  . PHE F 2 57  ? 222.926 274.131 266.441 1.00 33.33  ? 55  PHE F CZ  1 
ATOM   15079 N  N   . ASN F 2 58  ? 224.863 270.909 271.337 1.00 36.77  ? 56  ASN F N   1 
ATOM   15080 C  CA  . ASN F 2 58  ? 225.742 271.703 272.187 1.00 34.58  ? 56  ASN F CA  1 
ATOM   15081 C  C   . ASN F 2 58  ? 227.165 271.163 272.160 1.00 36.72  ? 56  ASN F C   1 
ATOM   15082 O  O   . ASN F 2 58  ? 228.130 271.927 272.054 1.00 38.20  ? 56  ASN F O   1 
ATOM   15083 C  CB  . ASN F 2 58  ? 225.199 271.735 273.615 1.00 33.28  ? 56  ASN F CB  1 
ATOM   15084 C  CG  . ASN F 2 58  ? 224.037 272.691 273.771 1.00 47.57  ? 56  ASN F CG  1 
ATOM   15085 O  OD1 . ASN F 2 58  ? 223.851 273.597 272.959 1.00 50.18  ? 56  ASN F OD1 1 
ATOM   15086 N  ND2 . ASN F 2 58  ? 223.240 272.488 274.813 1.00 51.31  ? 56  ASN F ND2 1 
ATOM   15087 N  N   . ARG F 2 59  ? 227.317 269.840 272.257 1.00 38.49  ? 57  ARG F N   1 
ATOM   15088 C  CA  . ARG F 2 59  ? 228.646 269.250 272.169 1.00 36.80  ? 57  ARG F CA  1 
ATOM   15089 C  C   . ARG F 2 59  ? 229.289 269.536 270.820 1.00 39.43  ? 57  ARG F C   1 
ATOM   15090 O  O   . ARG F 2 59  ? 230.517 269.629 270.724 1.00 46.73  ? 57  ARG F O   1 
ATOM   15091 C  CB  . ARG F 2 59  ? 228.560 267.746 272.427 1.00 33.08  ? 57  ARG F CB  1 
ATOM   15092 C  CG  . ARG F 2 59  ? 229.700 266.932 271.852 1.00 43.71  ? 57  ARG F CG  1 
ATOM   15093 C  CD  . ARG F 2 59  ? 229.420 265.448 272.010 1.00 45.46  ? 57  ARG F CD  1 
ATOM   15094 N  NE  . ARG F 2 59  ? 228.414 265.201 273.037 1.00 46.98  ? 57  ARG F NE  1 
ATOM   15095 C  CZ  . ARG F 2 59  ? 227.323 264.469 272.858 1.00 50.14  ? 57  ARG F CZ  1 
ATOM   15096 N  NH1 . ARG F 2 59  ? 227.061 263.890 271.698 1.00 46.30  ? 57  ARG F NH1 1 
ATOM   15097 N  NH2 . ARG F 2 59  ? 226.473 264.314 273.869 1.00 41.54  ? 57  ARG F NH2 1 
ATOM   15098 N  N   . ARG F 2 60  ? 228.478 269.684 269.772 1.00 39.02  ? 58  ARG F N   1 
ATOM   15099 C  CA  . ARG F 2 60  ? 228.998 270.049 268.461 1.00 40.75  ? 58  ARG F CA  1 
ATOM   15100 C  C   . ARG F 2 60  ? 229.350 271.528 268.356 1.00 42.09  ? 58  ARG F C   1 
ATOM   15101 O  O   . ARG F 2 60  ? 230.145 271.901 267.487 1.00 42.42  ? 58  ARG F O   1 
ATOM   15102 C  CB  . ARG F 2 60  ? 227.977 269.680 267.383 1.00 40.36  ? 58  ARG F CB  1 
ATOM   15103 C  CG  . ARG F 2 60  ? 228.212 270.332 266.035 1.00 43.03  ? 58  ARG F CG  1 
ATOM   15104 C  CD  . ARG F 2 60  ? 227.585 269.514 264.920 1.00 41.83  ? 58  ARG F CD  1 
ATOM   15105 N  NE  . ARG F 2 60  ? 226.370 268.841 265.363 1.00 42.14  ? 58  ARG F NE  1 
ATOM   15106 C  CZ  . ARG F 2 60  ? 225.141 269.247 265.078 1.00 44.14  ? 58  ARG F CZ  1 
ATOM   15107 N  NH1 . ARG F 2 60  ? 224.922 270.329 264.349 1.00 37.58  ? 58  ARG F NH1 1 
ATOM   15108 N  NH2 . ARG F 2 60  ? 224.105 268.553 265.539 1.00 42.85  ? 58  ARG F NH2 1 
ATOM   15109 N  N   . LEU F 2 61  ? 228.790 272.373 269.220 1.00 43.69  ? 59  LEU F N   1 
ATOM   15110 C  CA  . LEU F 2 61  ? 228.994 273.815 269.141 1.00 39.15  ? 59  LEU F CA  1 
ATOM   15111 C  C   . LEU F 2 61  ? 230.127 274.319 270.030 1.00 46.49  ? 59  LEU F C   1 
ATOM   15112 O  O   . LEU F 2 61  ? 230.259 275.534 270.210 1.00 49.41  ? 59  LEU F O   1 
ATOM   15113 C  CB  . LEU F 2 61  ? 227.700 274.549 269.499 1.00 37.81  ? 59  LEU F CB  1 
ATOM   15114 C  CG  . LEU F 2 61  ? 226.650 274.652 268.392 1.00 43.62  ? 59  LEU F CG  1 
ATOM   15115 C  CD1 . LEU F 2 61  ? 225.650 275.748 268.708 1.00 41.04  ? 59  LEU F CD1 1 
ATOM   15116 C  CD2 . LEU F 2 61  ? 227.307 274.891 267.041 1.00 41.63  ? 59  LEU F CD2 1 
ATOM   15117 N  N   . THR F 2 62  ? 230.939 273.430 270.593 1.00 47.88  ? 60  THR F N   1 
ATOM   15118 C  CA  . THR F 2 62  ? 232.034 273.843 271.457 1.00 45.66  ? 60  THR F CA  1 
ATOM   15119 C  C   . THR F 2 62  ? 233.307 274.062 270.648 1.00 49.99  ? 60  THR F C   1 
ATOM   15120 O  O   . THR F 2 62  ? 233.492 273.484 269.573 1.00 49.67  ? 60  THR F O   1 
ATOM   15121 C  CB  . THR F 2 62  ? 232.292 272.804 272.549 1.00 52.56  ? 60  THR F CB  1 
ATOM   15122 O  OG1 . THR F 2 62  ? 232.990 271.684 271.992 1.00 54.59  ? 60  THR F OG1 1 
ATOM   15123 C  CG2 . THR F 2 62  ? 230.980 272.330 273.152 1.00 41.21  ? 60  THR F CG2 1 
ATOM   15124 N  N   . GLN F 2 63  ? 234.186 274.908 271.178 1.00 50.66  ? 61  GLN F N   1 
ATOM   15125 C  CA  . GLN F 2 63  ? 235.461 275.202 270.538 1.00 48.29  ? 61  GLN F CA  1 
ATOM   15126 C  C   . GLN F 2 63  ? 236.548 274.311 271.122 1.00 51.35  ? 61  GLN F C   1 
ATOM   15127 O  O   . GLN F 2 63  ? 236.704 274.230 272.345 1.00 54.65  ? 61  GLN F O   1 
ATOM   15128 C  CB  . GLN F 2 63  ? 235.838 276.672 270.720 1.00 40.17  ? 61  GLN F CB  1 
ATOM   15129 C  CG  . GLN F 2 63  ? 234.665 277.627 270.760 1.00 34.35  ? 61  GLN F CG  1 
ATOM   15130 C  CD  . GLN F 2 63  ? 235.104 279.074 270.792 1.00 35.00  ? 61  GLN F CD  1 
ATOM   15131 O  OE1 . GLN F 2 63  ? 235.841 279.530 269.920 1.00 35.78  ? 61  GLN F OE1 1 
ATOM   15132 N  NE2 . GLN F 2 63  ? 234.662 279.803 271.807 1.00 33.91  ? 61  GLN F NE2 1 
ATOM   15133 N  N   . LYS F 2 64  ? 237.297 273.647 270.247 1.00 52.27  ? 62  LYS F N   1 
ATOM   15134 C  CA  . LYS F 2 64  ? 238.381 272.758 270.646 1.00 52.12  ? 62  LYS F CA  1 
ATOM   15135 C  C   . LYS F 2 64  ? 239.695 273.318 270.124 1.00 54.33  ? 62  LYS F C   1 
ATOM   15136 O  O   . LYS F 2 64  ? 239.857 273.504 268.913 1.00 58.32  ? 62  LYS F O   1 
ATOM   15137 C  CB  . LYS F 2 64  ? 238.149 271.341 270.120 1.00 55.37  ? 62  LYS F CB  1 
ATOM   15138 C  CG  . LYS F 2 64  ? 236.936 270.651 270.717 1.00 56.93  ? 62  LYS F CG  1 
ATOM   15139 C  CD  . LYS F 2 64  ? 235.843 270.456 269.678 1.00 57.69  ? 62  LYS F CD  1 
ATOM   15140 C  CE  . LYS F 2 64  ? 234.701 269.621 270.231 1.00 57.14  ? 62  LYS F CE  1 
ATOM   15141 N  NZ  . LYS F 2 64  ? 233.380 270.055 269.699 1.00 47.69  ? 62  LYS F NZ  1 
ATOM   15142 N  N   . THR F 2 65  ? 240.631 273.579 271.035 1.00 52.66  ? 63  THR F N   1 
ATOM   15143 C  CA  . THR F 2 65  ? 241.950 274.099 270.698 1.00 54.45  ? 63  THR F CA  1 
ATOM   15144 C  C   . THR F 2 65  ? 243.047 273.078 270.985 1.00 57.52  ? 63  THR F C   1 
ATOM   15145 O  O   . THR F 2 65  ? 244.166 273.443 271.353 1.00 57.12  ? 63  THR F O   1 
ATOM   15146 C  CB  . THR F 2 65  ? 242.218 275.400 271.454 1.00 50.14  ? 63  THR F CB  1 
ATOM   15147 O  OG1 . THR F 2 65  ? 242.817 275.105 272.722 1.00 55.17  ? 63  THR F OG1 1 
ATOM   15148 C  CG2 . THR F 2 65  ? 240.919 276.153 271.687 1.00 42.92  ? 63  THR F CG2 1 
ATOM   15149 N  N   . ASP F 2 66  ? 242.738 271.792 270.811 1.00 56.51  ? 64  ASP F N   1 
ATOM   15150 C  CA  . ASP F 2 66  ? 243.643 270.739 271.262 1.00 60.67  ? 64  ASP F CA  1 
ATOM   15151 C  C   . ASP F 2 66  ? 244.941 270.731 270.461 1.00 61.74  ? 64  ASP F C   1 
ATOM   15152 O  O   . ASP F 2 66  ? 246.035 270.721 271.037 1.00 62.84  ? 64  ASP F O   1 
ATOM   15153 C  CB  . ASP F 2 66  ? 242.946 269.382 271.171 1.00 63.79  ? 64  ASP F CB  1 
ATOM   15154 C  CG  . ASP F 2 66  ? 242.312 268.965 272.482 1.00 72.61  ? 64  ASP F CG  1 
ATOM   15155 O  OD1 . ASP F 2 66  ? 242.940 269.173 273.541 1.00 71.63  ? 64  ASP F OD1 1 
ATOM   15156 O  OD2 . ASP F 2 66  ? 241.183 268.432 272.454 1.00 77.68  ? 64  ASP F OD2 1 
ATOM   15157 N  N   . ASN F 2 67  ? 244.842 270.737 269.133 1.00 54.32  ? 65  ASN F N   1 
ATOM   15158 C  CA  . ASN F 2 67  ? 246.002 270.587 268.263 1.00 50.14  ? 65  ASN F CA  1 
ATOM   15159 C  C   . ASN F 2 67  ? 246.376 271.891 267.564 1.00 46.50  ? 65  ASN F C   1 
ATOM   15160 O  O   . ASN F 2 67  ? 246.990 271.873 266.495 1.00 44.02  ? 65  ASN F O   1 
ATOM   15161 C  CB  . ASN F 2 67  ? 245.753 269.488 267.232 1.00 57.57  ? 65  ASN F CB  1 
ATOM   15162 C  CG  . ASN F 2 67  ? 245.946 268.099 267.802 1.00 64.63  ? 65  ASN F CG  1 
ATOM   15163 O  OD1 . ASN F 2 67  ? 246.040 267.922 269.017 1.00 64.44  ? 65  ASN F OD1 1 
ATOM   15164 N  ND2 . ASN F 2 67  ? 246.002 267.103 266.927 1.00 66.86  ? 65  ASN F ND2 1 
ATOM   15165 N  N   . ALA F 2 68  ? 246.015 273.023 268.151 1.00 46.73  ? 66  ALA F N   1 
ATOM   15166 C  CA  . ALA F 2 68  ? 246.323 274.305 267.536 1.00 35.90  ? 66  ALA F CA  1 
ATOM   15167 C  C   . ALA F 2 68  ? 247.834 274.474 267.410 1.00 36.81  ? 66  ALA F C   1 
ATOM   15168 O  O   . ALA F 2 68  ? 248.554 274.334 268.408 1.00 38.60  ? 66  ALA F O   1 
ATOM   15169 C  CB  . ALA F 2 68  ? 245.731 275.449 268.356 1.00 36.43  ? 66  ALA F CB  1 
ATOM   15170 N  N   . PRO F 2 69  ? 248.354 274.767 266.213 1.00 33.45  ? 67  PRO F N   1 
ATOM   15171 C  CA  . PRO F 2 69  ? 249.793 275.024 266.073 1.00 27.04  ? 67  PRO F CA  1 
ATOM   15172 C  C   . PRO F 2 69  ? 250.222 276.393 266.572 1.00 33.56  ? 67  PRO F C   1 
ATOM   15173 O  O   . PRO F 2 69  ? 251.430 276.647 266.665 1.00 37.20  ? 67  PRO F O   1 
ATOM   15174 C  CB  . PRO F 2 69  ? 250.033 274.895 264.557 1.00 27.38  ? 67  PRO F CB  1 
ATOM   15175 C  CG  . PRO F 2 69  ? 248.713 274.505 263.949 1.00 31.39  ? 67  PRO F CG  1 
ATOM   15176 C  CD  . PRO F 2 69  ? 247.648 274.851 264.927 1.00 32.33  ? 67  PRO F CD  1 
ATOM   15177 N  N   . TRP F 2 70  ? 249.279 277.278 266.883 1.00 30.92  ? 68  TRP F N   1 
ATOM   15178 C  CA  . TRP F 2 70  ? 249.584 278.599 267.411 1.00 27.84  ? 68  TRP F CA  1 
ATOM   15179 C  C   . TRP F 2 70  ? 248.555 278.953 268.472 1.00 28.60  ? 68  TRP F C   1 
ATOM   15180 O  O   . TRP F 2 70  ? 247.351 278.810 268.243 1.00 34.18  ? 68  TRP F O   1 
ATOM   15181 C  CB  . TRP F 2 70  ? 249.591 279.653 266.299 1.00 26.94  ? 68  TRP F CB  1 
ATOM   15182 C  CG  . TRP F 2 70  ? 249.723 281.054 266.799 1.00 27.07  ? 68  TRP F CG  1 
ATOM   15183 C  CD1 . TRP F 2 70  ? 250.878 281.722 267.067 1.00 26.44  ? 68  TRP F CD1 1 
ATOM   15184 C  CD2 . TRP F 2 70  ? 248.656 281.964 267.089 1.00 28.27  ? 68  TRP F CD2 1 
ATOM   15185 N  NE1 . TRP F 2 70  ? 250.599 282.991 267.508 1.00 25.16  ? 68  TRP F NE1 1 
ATOM   15186 C  CE2 . TRP F 2 70  ? 249.241 283.164 267.531 1.00 25.03  ? 68  TRP F CE2 1 
ATOM   15187 C  CE3 . TRP F 2 70  ? 247.264 281.878 267.018 1.00 23.42  ? 68  TRP F CE3 1 
ATOM   15188 C  CZ2 . TRP F 2 70  ? 248.482 284.271 267.898 1.00 25.69  ? 68  TRP F CZ2 1 
ATOM   15189 C  CZ3 . TRP F 2 70  ? 246.514 282.975 267.385 1.00 24.68  ? 68  TRP F CZ3 1 
ATOM   15190 C  CH2 . TRP F 2 70  ? 247.123 284.156 267.818 1.00 26.82  ? 68  TRP F CH2 1 
ATOM   15191 N  N   . ARG F 2 71  ? 249.033 279.407 269.627 1.00 30.26  ? 69  ARG F N   1 
ATOM   15192 C  CA  . ARG F 2 71  ? 248.169 279.798 270.729 1.00 29.01  ? 69  ARG F CA  1 
ATOM   15193 C  C   . ARG F 2 71  ? 248.689 281.090 271.338 1.00 29.31  ? 69  ARG F C   1 
ATOM   15194 O  O   . ARG F 2 71  ? 249.877 281.406 271.253 1.00 31.71  ? 69  ARG F O   1 
ATOM   15195 C  CB  . ARG F 2 71  ? 248.099 278.720 271.818 1.00 31.62  ? 69  ARG F CB  1 
ATOM   15196 C  CG  . ARG F 2 71  ? 247.114 277.604 271.557 1.00 33.86  ? 69  ARG F CG  1 
ATOM   15197 C  CD  . ARG F 2 71  ? 247.449 276.391 272.407 1.00 40.29  ? 69  ARG F CD  1 
ATOM   15198 N  NE  . ARG F 2 71  ? 246.697 276.380 273.656 1.00 50.18  ? 69  ARG F NE  1 
ATOM   15199 C  CZ  . ARG F 2 71  ? 247.009 277.096 274.728 1.00 45.29  ? 69  ARG F CZ  1 
ATOM   15200 N  NH1 . ARG F 2 71  ? 248.067 277.890 274.746 1.00 43.18  ? 69  ARG F NH1 1 
ATOM   15201 N  NH2 . ARG F 2 71  ? 246.241 277.012 275.810 1.00 45.76  ? 69  ARG F NH2 1 
ATOM   15202 N  N   . ARG F 2 72  ? 247.781 281.832 271.963 1.00 29.99  ? 70  ARG F N   1 
ATOM   15203 C  CA  . ARG F 2 72  ? 248.177 283.013 272.726 1.00 26.70  ? 70  ARG F CA  1 
ATOM   15204 C  C   . ARG F 2 72  ? 247.105 283.304 273.760 1.00 24.69  ? 70  ARG F C   1 
ATOM   15205 O  O   . ARG F 2 72  ? 245.942 283.512 273.404 1.00 29.01  ? 70  ARG F O   1 
ATOM   15206 C  CB  . ARG F 2 72  ? 248.392 284.215 271.812 1.00 28.32  ? 70  ARG F CB  1 
ATOM   15207 C  CG  . ARG F 2 72  ? 249.801 284.309 271.259 1.00 28.11  ? 70  ARG F CG  1 
ATOM   15208 C  CD  . ARG F 2 72  ? 250.143 285.723 270.852 1.00 28.40  ? 70  ARG F CD  1 
ATOM   15209 N  NE  . ARG F 2 72  ? 250.787 286.456 271.933 1.00 30.04  ? 70  ARG F NE  1 
ATOM   15210 C  CZ  . ARG F 2 72  ? 251.194 287.714 271.844 1.00 28.69  ? 70  ARG F CZ  1 
ATOM   15211 N  NH1 . ARG F 2 72  ? 251.040 288.412 270.731 1.00 29.98  ? 70  ARG F NH1 1 
ATOM   15212 N  NH2 . ARG F 2 72  ? 251.770 288.285 272.896 1.00 27.51  ? 70  ARG F NH2 1 
ATOM   15213 N  N   . VAL F 2 73  ? 247.490 283.317 275.031 1.00 26.87  ? 71  VAL F N   1 
ATOM   15214 C  CA  . VAL F 2 73  ? 246.583 283.623 276.129 1.00 27.83  ? 71  VAL F CA  1 
ATOM   15215 C  C   . VAL F 2 73  ? 246.718 285.099 276.469 1.00 29.40  ? 71  VAL F C   1 
ATOM   15216 O  O   . VAL F 2 73  ? 247.833 285.608 276.636 1.00 34.07  ? 71  VAL F O   1 
ATOM   15217 C  CB  . VAL F 2 73  ? 246.873 282.741 277.354 1.00 29.30  ? 71  VAL F CB  1 
ATOM   15218 C  CG1 . VAL F 2 73  ? 246.040 283.194 278.537 1.00 32.20  ? 71  VAL F CG1 1 
ATOM   15219 C  CG2 . VAL F 2 73  ? 246.592 281.285 277.027 1.00 27.83  ? 71  VAL F CG2 1 
ATOM   15220 N  N   . VAL F 2 74  ? 245.584 285.787 276.565 1.00 29.91  ? 72  VAL F N   1 
ATOM   15221 C  CA  . VAL F 2 74  ? 245.537 287.225 276.793 1.00 29.46  ? 72  VAL F CA  1 
ATOM   15222 C  C   . VAL F 2 74  ? 244.548 287.515 277.913 1.00 28.63  ? 72  VAL F C   1 
ATOM   15223 O  O   . VAL F 2 74  ? 243.471 286.913 277.976 1.00 31.97  ? 72  VAL F O   1 
ATOM   15224 C  CB  . VAL F 2 74  ? 245.147 287.987 275.509 1.00 30.30  ? 72  VAL F CB  1 
ATOM   15225 C  CG1 . VAL F 2 74  ? 245.008 289.471 275.791 1.00 33.60  ? 72  VAL F CG1 1 
ATOM   15226 C  CG2 . VAL F 2 74  ? 246.178 287.748 274.420 1.00 29.98  ? 72  VAL F CG2 1 
ATOM   15227 N  N   . TYR F 2 75  ? 244.914 288.431 278.802 1.00 30.01  ? 73  TYR F N   1 
ATOM   15228 C  CA  . TYR F 2 75  ? 244.047 288.871 279.885 1.00 26.20  ? 73  TYR F CA  1 
ATOM   15229 C  C   . TYR F 2 75  ? 243.585 290.287 279.588 1.00 27.19  ? 73  TYR F C   1 
ATOM   15230 O  O   . TYR F 2 75  ? 244.411 291.176 279.355 1.00 30.41  ? 73  TYR F O   1 
ATOM   15231 C  CB  . TYR F 2 75  ? 244.776 288.828 281.228 1.00 26.82  ? 73  TYR F CB  1 
ATOM   15232 C  CG  . TYR F 2 75  ? 245.216 287.449 281.651 1.00 30.36  ? 73  TYR F CG  1 
ATOM   15233 C  CD1 . TYR F 2 75  ? 246.282 286.818 281.025 1.00 28.70  ? 73  TYR F CD1 1 
ATOM   15234 C  CD2 . TYR F 2 75  ? 244.579 286.784 282.687 1.00 33.01  ? 73  TYR F CD2 1 
ATOM   15235 C  CE1 . TYR F 2 75  ? 246.691 285.561 281.411 1.00 29.24  ? 73  TYR F CE1 1 
ATOM   15236 C  CE2 . TYR F 2 75  ? 244.982 285.527 283.080 1.00 31.53  ? 73  TYR F CE2 1 
ATOM   15237 C  CZ  . TYR F 2 75  ? 246.038 284.920 282.440 1.00 33.87  ? 73  TYR F CZ  1 
ATOM   15238 O  OH  . TYR F 2 75  ? 246.440 283.666 282.833 1.00 36.08  ? 73  TYR F OH  1 
ATOM   15239 N  N   . ARG F 2 76  ? 242.275 290.495 279.591 1.00 27.70  ? 74  ARG F N   1 
ATOM   15240 C  CA  . ARG F 2 76  ? 241.697 291.785 279.256 1.00 26.64  ? 74  ARG F CA  1 
ATOM   15241 C  C   . ARG F 2 76  ? 240.862 292.298 280.418 1.00 28.01  ? 74  ARG F C   1 
ATOM   15242 O  O   . ARG F 2 76  ? 240.133 291.534 281.056 1.00 29.39  ? 74  ARG F O   1 
ATOM   15243 C  CB  . ARG F 2 76  ? 240.833 291.690 277.999 1.00 30.64  ? 74  ARG F CB  1 
ATOM   15244 C  CG  . ARG F 2 76  ? 241.623 291.564 276.714 1.00 32.46  ? 74  ARG F CG  1 
ATOM   15245 C  CD  . ARG F 2 76  ? 240.714 291.673 275.507 1.00 31.23  ? 74  ARG F CD  1 
ATOM   15246 N  NE  . ARG F 2 76  ? 241.407 291.334 274.271 1.00 33.39  ? 74  ARG F NE  1 
ATOM   15247 C  CZ  . ARG F 2 76  ? 241.974 292.219 273.465 1.00 35.99  ? 74  ARG F CZ  1 
ATOM   15248 N  NH1 . ARG F 2 76  ? 241.940 293.515 273.729 1.00 39.29  ? 74  ARG F NH1 1 
ATOM   15249 N  NH2 . ARG F 2 76  ? 242.589 291.795 272.366 1.00 30.55  ? 74  ARG F NH2 1 
ATOM   15250 N  N   . ARG F 2 77  ? 240.978 293.593 280.692 1.00 31.93  ? 75  ARG F N   1 
ATOM   15251 C  CA  . ARG F 2 77  ? 240.137 294.265 281.673 1.00 32.82  ? 75  ARG F CA  1 
ATOM   15252 C  C   . ARG F 2 77  ? 238.998 294.946 280.925 1.00 31.68  ? 75  ARG F C   1 
ATOM   15253 O  O   . ARG F 2 77  ? 239.214 295.936 280.219 1.00 33.69  ? 75  ARG F O   1 
ATOM   15254 C  CB  . ARG F 2 77  ? 240.938 295.272 282.494 1.00 33.47  ? 75  ARG F CB  1 
ATOM   15255 C  CG  . ARG F 2 77  ? 240.272 295.663 283.802 1.00 35.26  ? 75  ARG F CG  1 
ATOM   15256 C  CD  . ARG F 2 77  ? 241.055 296.748 284.517 1.00 37.62  ? 75  ARG F CD  1 
ATOM   15257 N  NE  . ARG F 2 77  ? 240.335 297.271 285.671 1.00 40.05  ? 75  ARG F NE  1 
ATOM   15258 C  CZ  . ARG F 2 77  ? 239.404 298.213 285.610 1.00 43.94  ? 75  ARG F CZ  1 
ATOM   15259 N  NH1 . ARG F 2 77  ? 239.054 298.764 284.460 1.00 43.73  ? 75  ARG F NH1 1 
ATOM   15260 N  NH2 . ARG F 2 77  ? 238.810 298.612 286.730 1.00 48.93  ? 75  ARG F NH2 1 
ATOM   15261 N  N   . VAL F 2 78  ? 237.792 294.412 281.076 1.00 32.26  ? 76  VAL F N   1 
ATOM   15262 C  CA  . VAL F 2 78  ? 236.600 294.960 280.443 1.00 33.73  ? 76  VAL F CA  1 
ATOM   15263 C  C   . VAL F 2 78  ? 235.924 295.878 281.449 1.00 33.91  ? 76  VAL F C   1 
ATOM   15264 O  O   . VAL F 2 78  ? 235.502 295.431 282.523 1.00 37.69  ? 76  VAL F O   1 
ATOM   15265 C  CB  . VAL F 2 78  ? 235.650 293.846 279.976 1.00 34.82  ? 76  VAL F CB  1 
ATOM   15266 C  CG1 . VAL F 2 78  ? 234.377 294.441 279.405 1.00 37.74  ? 76  VAL F CG1 1 
ATOM   15267 C  CG2 . VAL F 2 78  ? 236.337 292.959 278.951 1.00 33.71  ? 76  VAL F CG2 1 
ATOM   15268 N  N   . ASP F 2 79  ? 235.834 297.160 281.106 1.00 35.74  ? 77  ASP F N   1 
ATOM   15269 C  CA  . ASP F 2 79  ? 235.250 298.169 281.979 1.00 39.86  ? 77  ASP F CA  1 
ATOM   15270 C  C   . ASP F 2 79  ? 233.777 298.347 281.637 1.00 43.09  ? 77  ASP F C   1 
ATOM   15271 O  O   . ASP F 2 79  ? 233.426 298.576 280.476 1.00 44.63  ? 77  ASP F O   1 
ATOM   15272 C  CB  . ASP F 2 79  ? 235.998 299.494 281.836 1.00 41.69  ? 77  ASP F CB  1 
ATOM   15273 C  CG  . ASP F 2 79  ? 235.475 300.565 282.771 1.00 52.32  ? 77  ASP F CG  1 
ATOM   15274 O  OD1 . ASP F 2 79  ? 234.874 300.215 283.809 1.00 51.90  ? 77  ASP F OD1 1 
ATOM   15275 O  OD2 . ASP F 2 79  ? 235.665 301.759 282.465 1.00 59.08  ? 77  ASP F OD2 1 
ATOM   15276 N  N   . LEU F 2 80  ? 232.920 298.241 282.652 1.00 42.80  ? 78  LEU F N   1 
ATOM   15277 C  CA  . LEU F 2 80  ? 231.479 298.257 282.442 1.00 44.41  ? 78  LEU F CA  1 
ATOM   15278 C  C   . LEU F 2 80  ? 230.914 299.659 282.268 1.00 49.35  ? 78  LEU F C   1 
ATOM   15279 O  O   . LEU F 2 80  ? 229.737 299.793 281.916 1.00 52.61  ? 78  LEU F O   1 
ATOM   15280 C  CB  . LEU F 2 80  ? 230.772 297.563 283.608 1.00 43.38  ? 78  LEU F CB  1 
ATOM   15281 C  CG  . LEU F 2 80  ? 231.218 296.131 283.907 1.00 38.48  ? 78  LEU F CG  1 
ATOM   15282 C  CD1 . LEU F 2 80  ? 230.126 295.372 284.638 1.00 35.79  ? 78  LEU F CD1 1 
ATOM   15283 C  CD2 . LEU F 2 80  ? 231.606 295.413 282.627 1.00 39.77  ? 78  LEU F CD2 1 
ATOM   15284 N  N   . MET F 2 81  ? 231.711 300.699 282.504 1.00 52.87  ? 79  MET F N   1 
ATOM   15285 C  CA  . MET F 2 81  ? 231.269 302.075 282.341 1.00 51.87  ? 79  MET F CA  1 
ATOM   15286 C  C   . MET F 2 81  ? 231.454 302.586 280.918 1.00 55.41  ? 79  MET F C   1 
ATOM   15287 O  O   . MET F 2 81  ? 231.498 303.804 280.706 1.00 64.26  ? 79  MET F O   1 
ATOM   15288 C  CB  . MET F 2 81  ? 231.999 302.983 283.331 1.00 52.27  ? 79  MET F CB  1 
ATOM   15289 C  CG  . MET F 2 81  ? 231.618 302.731 284.779 1.00 59.53  ? 79  MET F CG  1 
ATOM   15290 S  SD  . MET F 2 81  ? 229.855 302.981 285.066 1.00 80.19  ? 79  MET F SD  1 
ATOM   15291 C  CE  . MET F 2 81  ? 229.490 301.613 286.161 1.00 51.64  ? 79  MET F CE  1 
ATOM   15292 N  N   . GLU F 2 82  ? 231.563 301.688 279.944 1.00 53.11  ? 80  GLU F N   1 
ATOM   15293 C  CA  . GLU F 2 82  ? 231.693 302.051 278.542 1.00 57.78  ? 80  GLU F CA  1 
ATOM   15294 C  C   . GLU F 2 82  ? 230.567 301.411 277.743 1.00 57.83  ? 80  GLU F C   1 
ATOM   15295 O  O   . GLU F 2 82  ? 230.173 300.273 278.012 1.00 56.56  ? 80  GLU F O   1 
ATOM   15296 C  CB  . GLU F 2 82  ? 233.043 301.608 277.977 1.00 56.08  ? 80  GLU F CB  1 
ATOM   15297 C  CG  . GLU F 2 82  ? 234.165 301.607 278.994 1.00 57.90  ? 80  GLU F CG  1 
ATOM   15298 C  CD  . GLU F 2 82  ? 235.532 301.612 278.346 1.00 67.66  ? 80  GLU F CD  1 
ATOM   15299 O  OE1 . GLU F 2 82  ? 235.738 300.839 277.388 1.00 68.28  ? 80  GLU F OE1 1 
ATOM   15300 O  OE2 . GLU F 2 82  ? 236.400 302.391 278.794 1.00 71.90  ? 80  GLU F OE2 1 
ATOM   15301 N  N   . GLU F 2 83  ? 230.051 302.146 276.763 1.00 63.13  ? 81  GLU F N   1 
ATOM   15302 C  CA  . GLU F 2 83  ? 229.033 301.591 275.885 1.00 65.08  ? 81  GLU F CA  1 
ATOM   15303 C  C   . GLU F 2 83  ? 229.591 300.392 275.126 1.00 61.58  ? 81  GLU F C   1 
ATOM   15304 O  O   . GLU F 2 83  ? 230.778 300.335 274.795 1.00 63.85  ? 81  GLU F O   1 
ATOM   15305 C  CB  . GLU F 2 83  ? 228.531 302.654 274.908 1.00 69.48  ? 81  GLU F CB  1 
ATOM   15306 C  CG  . GLU F 2 83  ? 227.090 302.458 274.471 1.00 68.72  ? 81  GLU F CG  1 
ATOM   15307 C  CD  . GLU F 2 83  ? 226.102 302.635 275.606 1.00 75.09  ? 81  GLU F CD  1 
ATOM   15308 O  OE1 . GLU F 2 83  ? 226.541 302.785 276.766 1.00 74.32  ? 81  GLU F OE1 1 
ATOM   15309 O  OE2 . GLU F 2 83  ? 224.884 302.623 275.337 1.00 70.96  ? 81  GLU F OE2 1 
ATOM   15310 N  N   . SER F 2 84  ? 228.720 299.425 274.857 1.00 56.06  ? 82  SER F N   1 
ATOM   15311 C  CA  . SER F 2 84  ? 229.047 298.118 274.295 1.00 56.45  ? 82  SER F CA  1 
ATOM   15312 C  C   . SER F 2 84  ? 229.651 297.214 275.362 1.00 52.67  ? 82  SER F C   1 
ATOM   15313 O  O   . SER F 2 84  ? 229.914 296.038 275.080 1.00 53.73  ? 82  SER F O   1 
ATOM   15314 C  CB  . SER F 2 84  ? 230.008 298.200 273.098 1.00 58.01  ? 82  SER F CB  1 
ATOM   15315 O  OG  . SER F 2 84  ? 231.355 298.045 273.510 1.00 54.59  ? 82  SER F OG  1 
ATOM   15316 N  N   . ASN F 2 85  ? 229.882 297.721 276.575 1.00 47.15  ? 83  ASN F N   1 
ATOM   15317 C  CA  . ASN F 2 85  ? 230.348 296.922 277.697 1.00 42.94  ? 83  ASN F CA  1 
ATOM   15318 C  C   . ASN F 2 85  ? 229.363 296.869 278.853 1.00 43.18  ? 83  ASN F C   1 
ATOM   15319 O  O   . ASN F 2 85  ? 229.476 295.971 279.692 1.00 45.27  ? 83  ASN F O   1 
ATOM   15320 C  CB  . ASN F 2 85  ? 231.686 297.460 278.227 1.00 47.94  ? 83  ASN F CB  1 
ATOM   15321 C  CG  . ASN F 2 85  ? 232.881 296.753 277.627 1.00 40.99  ? 83  ASN F CG  1 
ATOM   15322 O  OD1 . ASN F 2 85  ? 232.739 295.772 276.901 1.00 44.04  ? 83  ASN F OD1 1 
ATOM   15323 N  ND2 . ASN F 2 85  ? 234.071 297.253 277.931 1.00 40.46  ? 83  ASN F ND2 1 
ATOM   15324 N  N   . ALA F 2 86  ? 228.414 297.803 278.926 1.00 48.82  ? 84  ALA F N   1 
ATOM   15325 C  CA  . ALA F 2 86  ? 227.420 297.827 279.991 1.00 42.16  ? 84  ALA F CA  1 
ATOM   15326 C  C   . ALA F 2 86  ? 226.350 296.762 279.819 1.00 37.56  ? 84  ALA F C   1 
ATOM   15327 O  O   . ALA F 2 86  ? 225.431 296.696 280.641 1.00 42.09  ? 84  ALA F O   1 
ATOM   15328 C  CB  . ALA F 2 86  ? 226.771 299.209 280.070 1.00 37.91  ? 84  ALA F CB  1 
ATOM   15329 N  N   . VAL F 2 87  ? 226.445 295.935 278.777 1.00 35.80  ? 85  VAL F N   1 
ATOM   15330 C  CA  . VAL F 2 87  ? 225.498 294.839 278.606 1.00 35.10  ? 85  VAL F CA  1 
ATOM   15331 C  C   . VAL F 2 87  ? 225.527 293.921 279.820 1.00 35.82  ? 85  VAL F C   1 
ATOM   15332 O  O   . VAL F 2 87  ? 224.487 293.421 280.265 1.00 36.90  ? 85  VAL F O   1 
ATOM   15333 C  CB  . VAL F 2 87  ? 225.802 294.073 277.306 1.00 33.07  ? 85  VAL F CB  1 
ATOM   15334 C  CG1 . VAL F 2 87  ? 225.035 292.765 277.267 1.00 36.86  ? 85  VAL F CG1 1 
ATOM   15335 C  CG2 . VAL F 2 87  ? 225.466 294.929 276.098 1.00 35.20  ? 85  VAL F CG2 1 
ATOM   15336 N  N   . LEU F 2 88  ? 226.716 293.682 280.372 1.00 36.29  ? 86  LEU F N   1 
ATOM   15337 C  CA  . LEU F 2 88  ? 226.859 292.865 281.569 1.00 38.24  ? 86  LEU F CA  1 
ATOM   15338 C  C   . LEU F 2 88  ? 226.491 293.610 282.843 1.00 38.29  ? 86  LEU F C   1 
ATOM   15339 O  O   . LEU F 2 88  ? 226.439 292.990 283.910 1.00 42.29  ? 86  LEU F O   1 
ATOM   15340 C  CB  . LEU F 2 88  ? 228.293 292.346 281.686 1.00 36.42  ? 86  LEU F CB  1 
ATOM   15341 C  CG  . LEU F 2 88  ? 228.946 291.843 280.400 1.00 32.26  ? 86  LEU F CG  1 
ATOM   15342 C  CD1 . LEU F 2 88  ? 230.445 291.702 280.590 1.00 28.62  ? 86  LEU F CD1 1 
ATOM   15343 C  CD2 . LEU F 2 88  ? 228.327 290.525 279.974 1.00 30.59  ? 86  LEU F CD2 1 
ATOM   15344 N  N   . TYR F 2 89  ? 226.247 294.915 282.761 1.00 38.10  ? 87  TYR F N   1 
ATOM   15345 C  CA  . TYR F 2 89  ? 225.923 295.731 283.923 1.00 38.29  ? 87  TYR F CA  1 
ATOM   15346 C  C   . TYR F 2 89  ? 224.427 295.919 284.126 1.00 43.39  ? 87  TYR F C   1 
ATOM   15347 O  O   . TYR F 2 89  ? 223.962 295.940 285.269 1.00 45.91  ? 87  TYR F O   1 
ATOM   15348 C  CB  . TYR F 2 89  ? 226.595 297.102 283.800 1.00 39.48  ? 87  TYR F CB  1 
ATOM   15349 C  CG  . TYR F 2 89  ? 226.575 297.916 285.071 1.00 43.96  ? 87  TYR F CG  1 
ATOM   15350 C  CD1 . TYR F 2 89  ? 227.236 297.479 286.210 1.00 46.50  ? 87  TYR F CD1 1 
ATOM   15351 C  CD2 . TYR F 2 89  ? 225.899 299.126 285.129 1.00 40.84  ? 87  TYR F CD2 1 
ATOM   15352 C  CE1 . TYR F 2 89  ? 227.218 298.222 287.372 1.00 47.61  ? 87  TYR F CE1 1 
ATOM   15353 C  CE2 . TYR F 2 89  ? 225.877 299.875 286.284 1.00 46.68  ? 87  TYR F CE2 1 
ATOM   15354 C  CZ  . TYR F 2 89  ? 226.538 299.419 287.403 1.00 51.05  ? 87  TYR F CZ  1 
ATOM   15355 O  OH  . TYR F 2 89  ? 226.517 300.165 288.556 1.00 55.40  ? 87  TYR F OH  1 
ATOM   15356 N  N   . TYR F 2 90  ? 223.664 296.052 283.051 1.00 39.01  ? 88  TYR F N   1 
ATOM   15357 C  CA  . TYR F 2 90  ? 222.238 296.329 283.175 1.00 39.47  ? 88  TYR F CA  1 
ATOM   15358 C  C   . TYR F 2 90  ? 221.489 295.084 283.637 1.00 43.40  ? 88  TYR F C   1 
ATOM   15359 O  O   . TYR F 2 90  ? 221.663 294.010 283.051 1.00 45.40  ? 88  TYR F O   1 
ATOM   15360 C  CB  . TYR F 2 90  ? 221.673 296.812 281.843 1.00 37.67  ? 88  TYR F CB  1 
ATOM   15361 C  CG  . TYR F 2 90  ? 220.254 297.323 281.927 1.00 40.18  ? 88  TYR F CG  1 
ATOM   15362 C  CD1 . TYR F 2 90  ? 219.175 296.457 281.818 1.00 42.39  ? 88  TYR F CD1 1 
ATOM   15363 C  CD2 . TYR F 2 90  ? 219.992 298.672 282.107 1.00 39.16  ? 88  TYR F CD2 1 
ATOM   15364 C  CE1 . TYR F 2 90  ? 217.880 296.918 281.891 1.00 41.04  ? 88  TYR F CE1 1 
ATOM   15365 C  CE2 . TYR F 2 90  ? 218.699 299.144 282.182 1.00 41.11  ? 88  TYR F CE2 1 
ATOM   15366 C  CZ  . TYR F 2 90  ? 217.646 298.263 282.072 1.00 47.14  ? 88  TYR F CZ  1 
ATOM   15367 O  OH  . TYR F 2 90  ? 216.354 298.730 282.146 1.00 52.79  ? 88  TYR F OH  1 
ATOM   15368 N  N   . PRO F 2 91  ? 220.646 295.183 284.672 1.00 44.68  ? 89  PRO F N   1 
ATOM   15369 C  CA  . PRO F 2 91  ? 220.410 296.350 285.530 1.00 43.12  ? 89  PRO F CA  1 
ATOM   15370 C  C   . PRO F 2 91  ? 221.392 296.388 286.694 1.00 45.29  ? 89  PRO F C   1 
ATOM   15371 O  O   . PRO F 2 91  ? 221.825 295.342 287.168 1.00 50.94  ? 89  PRO F O   1 
ATOM   15372 C  CB  . PRO F 2 91  ? 218.956 296.151 286.005 1.00 43.63  ? 89  PRO F CB  1 
ATOM   15373 C  CG  . PRO F 2 91  ? 218.459 294.857 285.371 1.00 45.19  ? 89  PRO F CG  1 
ATOM   15374 C  CD  . PRO F 2 91  ? 219.690 294.109 284.966 1.00 41.72  ? 89  PRO F CD  1 
ATOM   15375 N  N   . PRO F 2 92  ? 221.760 297.574 287.181 1.00 43.95  ? 90  PRO F N   1 
ATOM   15376 C  CA  . PRO F 2 92  ? 222.696 297.632 288.316 1.00 49.77  ? 90  PRO F CA  1 
ATOM   15377 C  C   . PRO F 2 92  ? 222.201 296.872 289.531 1.00 48.41  ? 90  PRO F C   1 
ATOM   15378 O  O   . PRO F 2 92  ? 223.008 296.274 290.252 1.00 52.49  ? 90  PRO F O   1 
ATOM   15379 C  CB  . PRO F 2 92  ? 222.816 299.137 288.595 1.00 47.80  ? 90  PRO F CB  1 
ATOM   15380 C  CG  . PRO F 2 92  ? 222.410 299.795 287.318 1.00 44.87  ? 90  PRO F CG  1 
ATOM   15381 C  CD  . PRO F 2 92  ? 221.364 298.913 286.717 1.00 45.19  ? 90  PRO F CD  1 
ATOM   15382 N  N   . ARG F 2 93  ? 220.897 296.877 289.778 1.00 51.03  ? 91  ARG F N   1 
ATOM   15383 C  CA  . ARG F 2 93  ? 220.272 296.053 290.796 1.00 53.02  ? 91  ARG F CA  1 
ATOM   15384 C  C   . ARG F 2 93  ? 219.082 295.335 290.182 1.00 54.16  ? 91  ARG F C   1 
ATOM   15385 O  O   . ARG F 2 93  ? 218.473 295.838 289.232 1.00 52.03  ? 91  ARG F O   1 
ATOM   15386 C  CB  . ARG F 2 93  ? 219.816 296.889 292.000 1.00 56.45  ? 91  ARG F CB  1 
ATOM   15387 C  CG  . ARG F 2 93  ? 220.958 297.536 292.766 1.00 57.85  ? 91  ARG F CG  1 
ATOM   15388 C  CD  . ARG F 2 93  ? 220.723 297.483 294.264 1.00 60.60  ? 91  ARG F CD  1 
ATOM   15389 N  NE  . ARG F 2 93  ? 221.867 297.979 295.020 1.00 70.00  ? 91  ARG F NE  1 
ATOM   15390 C  CZ  . ARG F 2 93  ? 222.366 299.203 294.914 1.00 70.55  ? 91  ARG F CZ  1 
ATOM   15391 N  NH1 . ARG F 2 93  ? 221.842 300.094 294.088 1.00 68.29  ? 91  ARG F NH1 1 
ATOM   15392 N  NH2 . ARG F 2 93  ? 223.415 299.543 295.656 1.00 62.46  ? 91  ARG F NH2 1 
ATOM   15393 N  N   . PRO F 2 94  ? 218.729 294.162 290.701 1.00 58.46  ? 92  PRO F N   1 
ATOM   15394 C  CA  . PRO F 2 94  ? 217.702 293.350 290.039 1.00 56.53  ? 92  PRO F CA  1 
ATOM   15395 C  C   . PRO F 2 94  ? 216.392 294.110 289.891 1.00 61.12  ? 92  PRO F C   1 
ATOM   15396 O  O   . PRO F 2 94  ? 215.951 294.816 290.800 1.00 61.30  ? 92  PRO F O   1 
ATOM   15397 C  CB  . PRO F 2 94  ? 217.554 292.142 290.971 1.00 55.96  ? 92  PRO F CB  1 
ATOM   15398 C  CG  . PRO F 2 94  ? 218.857 292.072 291.700 1.00 57.97  ? 92  PRO F CG  1 
ATOM   15399 C  CD  . PRO F 2 94  ? 219.275 293.498 291.895 1.00 56.48  ? 92  PRO F CD  1 
ATOM   15400 N  N   . ILE F 2 95  ? 215.771 293.953 288.726 1.00 61.47  ? 93  ILE F N   1 
ATOM   15401 C  CA  . ILE F 2 95  ? 214.500 294.589 288.402 1.00 59.68  ? 93  ILE F CA  1 
ATOM   15402 C  C   . ILE F 2 95  ? 213.513 293.457 288.152 1.00 62.65  ? 93  ILE F C   1 
ATOM   15403 O  O   . ILE F 2 95  ? 213.455 292.903 287.047 1.00 66.53  ? 93  ILE F O   1 
ATOM   15404 C  CB  . ILE F 2 95  ? 214.607 295.520 287.189 1.00 57.59  ? 93  ILE F CB  1 
ATOM   15405 C  CG1 . ILE F 2 95  ? 215.138 296.891 287.608 1.00 53.87  ? 93  ILE F CG1 1 
ATOM   15406 C  CG2 . ILE F 2 95  ? 213.255 295.675 286.511 1.00 61.43  ? 93  ILE F CG2 1 
ATOM   15407 C  CD1 . ILE F 2 95  ? 215.153 297.906 286.486 1.00 50.99  ? 93  ILE F CD1 1 
ATOM   15408 N  N   . GLY F 2 96  ? 212.740 293.101 289.173 1.00 59.57  ? 94  GLY F N   1 
ATOM   15409 C  CA  . GLY F 2 96  ? 211.853 291.962 289.059 1.00 62.71  ? 94  GLY F CA  1 
ATOM   15410 C  C   . GLY F 2 96  ? 212.617 290.683 288.789 1.00 68.43  ? 94  GLY F C   1 
ATOM   15411 O  O   . GLY F 2 96  ? 213.314 290.170 289.670 1.00 70.33  ? 94  GLY F O   1 
ATOM   15412 N  N   . ASP F 2 97  ? 212.494 290.158 287.572 1.00 69.44  ? 95  ASP F N   1 
ATOM   15413 C  CA  . ASP F 2 97  ? 213.218 288.967 287.152 1.00 69.32  ? 95  ASP F CA  1 
ATOM   15414 C  C   . ASP F 2 97  ? 214.463 289.293 286.337 1.00 66.11  ? 95  ASP F C   1 
ATOM   15415 O  O   . ASP F 2 97  ? 215.098 288.378 285.803 1.00 64.91  ? 95  ASP F O   1 
ATOM   15416 C  CB  . ASP F 2 97  ? 212.297 288.046 286.350 1.00 75.69  ? 95  ASP F CB  1 
ATOM   15417 C  CG  . ASP F 2 97  ? 212.591 286.579 286.587 1.00 84.85  ? 95  ASP F CG  1 
ATOM   15418 O  OD1 . ASP F 2 97  ? 213.672 286.115 286.169 1.00 87.52  ? 95  ASP F OD1 1 
ATOM   15419 O  OD2 . ASP F 2 97  ? 211.743 285.890 287.190 1.00 86.21  ? 95  ASP F OD2 1 
ATOM   15420 N  N   . ARG F 2 98  ? 214.826 290.568 286.229 1.00 64.30  ? 96  ARG F N   1 
ATOM   15421 C  CA  . ARG F 2 98  ? 215.949 291.002 285.409 1.00 58.85  ? 96  ARG F CA  1 
ATOM   15422 C  C   . ARG F 2 98  ? 217.163 291.242 286.298 1.00 53.51  ? 96  ARG F C   1 
ATOM   15423 O  O   . ARG F 2 98  ? 217.127 292.101 287.186 1.00 51.96  ? 96  ARG F O   1 
ATOM   15424 C  CB  . ARG F 2 98  ? 215.592 292.269 284.633 1.00 59.04  ? 96  ARG F CB  1 
ATOM   15425 C  CG  . ARG F 2 98  ? 215.452 292.059 283.139 1.00 56.83  ? 96  ARG F CG  1 
ATOM   15426 C  CD  . ARG F 2 98  ? 215.295 293.378 282.409 1.00 53.27  ? 96  ARG F CD  1 
ATOM   15427 N  NE  . ARG F 2 98  ? 216.169 293.453 281.245 1.00 57.41  ? 96  ARG F NE  1 
ATOM   15428 C  CZ  . ARG F 2 98  ? 216.109 294.400 280.319 1.00 57.90  ? 96  ARG F CZ  1 
ATOM   15429 N  NH1 . ARG F 2 98  ? 215.216 295.373 280.382 1.00 54.38  ? 96  ARG F NH1 1 
ATOM   15430 N  NH2 . ARG F 2 98  ? 216.968 294.370 279.305 1.00 51.01  ? 96  ARG F NH2 1 
ATOM   15431 N  N   . LYS F 2 99  ? 218.232 290.487 286.057 1.00 51.66  ? 97  LYS F N   1 
ATOM   15432 C  CA  . LYS F 2 99  ? 219.474 290.623 286.802 1.00 46.39  ? 97  LYS F CA  1 
ATOM   15433 C  C   . LYS F 2 99  ? 220.636 290.766 285.831 1.00 46.11  ? 97  LYS F C   1 
ATOM   15434 O  O   . LYS F 2 99  ? 220.579 290.285 284.697 1.00 48.49  ? 97  LYS F O   1 
ATOM   15435 C  CB  . LYS F 2 99  ? 219.723 289.418 287.717 1.00 42.19  ? 97  LYS F CB  1 
ATOM   15436 C  CG  . LYS F 2 99  ? 218.699 289.239 288.819 1.00 47.56  ? 97  LYS F CG  1 
ATOM   15437 C  CD  . LYS F 2 99  ? 219.186 288.241 289.856 1.00 49.47  ? 97  LYS F CD  1 
ATOM   15438 C  CE  . LYS F 2 99  ? 219.245 286.832 289.288 1.00 51.42  ? 97  LYS F CE  1 
ATOM   15439 N  NZ  . LYS F 2 99  ? 218.437 286.693 288.049 1.00 50.79  ? 97  LYS F NZ  1 
ATOM   15440 N  N   . ASN F 2 100 ? 221.693 291.434 286.285 1.00 41.76  ? 98  ASN F N   1 
ATOM   15441 C  CA  . ASN F 2 100 ? 222.908 291.534 285.496 1.00 38.60  ? 98  ASN F CA  1 
ATOM   15442 C  C   . ASN F 2 100 ? 223.777 290.299 285.731 1.00 37.50  ? 98  ASN F C   1 
ATOM   15443 O  O   . ASN F 2 100 ? 223.381 289.348 286.408 1.00 39.70  ? 98  ASN F O   1 
ATOM   15444 C  CB  . ASN F 2 100 ? 223.645 292.839 285.805 1.00 39.35  ? 98  ASN F CB  1 
ATOM   15445 C  CG  . ASN F 2 100 ? 224.148 292.918 287.234 1.00 40.61  ? 98  ASN F CG  1 
ATOM   15446 O  OD1 . ASN F 2 100 ? 224.185 291.923 287.955 1.00 44.91  ? 98  ASN F OD1 1 
ATOM   15447 N  ND2 . ASN F 2 100 ? 224.538 294.116 287.650 1.00 41.65  ? 98  ASN F ND2 1 
ATOM   15448 N  N   . LEU F 2 101 ? 224.977 290.303 285.147 1.00 38.24  ? 99  LEU F N   1 
ATOM   15449 C  CA  . LEU F 2 101 ? 225.817 289.109 285.181 1.00 38.58  ? 99  LEU F CA  1 
ATOM   15450 C  C   . LEU F 2 101 ? 226.219 288.743 286.605 1.00 37.79  ? 99  LEU F C   1 
ATOM   15451 O  O   . LEU F 2 101 ? 226.174 287.567 286.989 1.00 39.10  ? 99  LEU F O   1 
ATOM   15452 C  CB  . LEU F 2 101 ? 227.055 289.319 284.310 1.00 34.86  ? 99  LEU F CB  1 
ATOM   15453 C  CG  . LEU F 2 101 ? 228.093 288.198 284.307 1.00 33.43  ? 99  LEU F CG  1 
ATOM   15454 C  CD1 . LEU F 2 101 ? 227.447 286.865 283.970 1.00 27.85  ? 99  LEU F CD1 1 
ATOM   15455 C  CD2 . LEU F 2 101 ? 229.216 288.516 283.334 1.00 30.81  ? 99  LEU F CD2 1 
ATOM   15456 N  N   . PHE F 2 102 ? 226.608 289.733 287.410 1.00 38.38  ? 100 PHE F N   1 
ATOM   15457 C  CA  . PHE F 2 102 ? 227.055 289.418 288.761 1.00 39.65  ? 100 PHE F CA  1 
ATOM   15458 C  C   . PHE F 2 102 ? 225.902 288.981 289.651 1.00 40.84  ? 100 PHE F C   1 
ATOM   15459 O  O   . PHE F 2 102 ? 226.098 288.158 290.548 1.00 44.13  ? 100 PHE F O   1 
ATOM   15460 C  CB  . PHE F 2 102 ? 227.779 290.602 289.393 1.00 38.52  ? 100 PHE F CB  1 
ATOM   15461 C  CG  . PHE F 2 102 ? 228.393 290.277 290.722 1.00 44.80  ? 100 PHE F CG  1 
ATOM   15462 C  CD1 . PHE F 2 102 ? 229.532 289.494 290.798 1.00 44.20  ? 100 PHE F CD1 1 
ATOM   15463 C  CD2 . PHE F 2 102 ? 227.817 290.729 291.895 1.00 47.74  ? 100 PHE F CD2 1 
ATOM   15464 C  CE1 . PHE F 2 102 ? 230.093 289.182 292.019 1.00 46.16  ? 100 PHE F CE1 1 
ATOM   15465 C  CE2 . PHE F 2 102 ? 228.375 290.419 293.119 1.00 48.26  ? 100 PHE F CE2 1 
ATOM   15466 C  CZ  . PHE F 2 102 ? 229.514 289.645 293.180 1.00 50.29  ? 100 PHE F CZ  1 
ATOM   15467 N  N   . SER F 2 103 ? 224.704 289.522 289.435 1.00 41.75  ? 101 SER F N   1 
ATOM   15468 C  CA  . SER F 2 103 ? 223.552 289.040 290.188 1.00 40.78  ? 101 SER F CA  1 
ATOM   15469 C  C   . SER F 2 103 ? 223.306 287.564 289.910 1.00 44.17  ? 101 SER F C   1 
ATOM   15470 O  O   . SER F 2 103 ? 223.066 286.780 290.835 1.00 48.33  ? 101 SER F O   1 
ATOM   15471 C  CB  . SER F 2 103 ? 222.316 289.869 289.848 1.00 42.01  ? 101 SER F CB  1 
ATOM   15472 O  OG  . SER F 2 103 ? 222.393 291.158 290.428 1.00 48.17  ? 101 SER F OG  1 
ATOM   15473 N  N   . THR F 2 104 ? 223.384 287.164 288.639 1.00 39.56  ? 102 THR F N   1 
ATOM   15474 C  CA  . THR F 2 104 ? 223.246 285.755 288.291 1.00 40.95  ? 102 THR F CA  1 
ATOM   15475 C  C   . THR F 2 104 ? 224.346 284.918 288.931 1.00 43.52  ? 102 THR F C   1 
ATOM   15476 O  O   . THR F 2 104 ? 224.083 283.828 289.454 1.00 50.68  ? 102 THR F O   1 
ATOM   15477 C  CB  . THR F 2 104 ? 223.266 285.586 286.773 1.00 42.40  ? 102 THR F CB  1 
ATOM   15478 O  OG1 . THR F 2 104 ? 222.296 286.459 286.181 1.00 49.71  ? 102 THR F OG1 1 
ATOM   15479 C  CG2 . THR F 2 104 ? 222.954 284.149 286.390 1.00 42.50  ? 102 THR F CG2 1 
ATOM   15480 N  N   . ILE F 2 105 ? 225.586 285.407 288.894 1.00 45.56  ? 103 ILE F N   1 
ATOM   15481 C  CA  . ILE F 2 105 ? 226.700 284.651 289.461 1.00 44.25  ? 103 ILE F CA  1 
ATOM   15482 C  C   . ILE F 2 105 ? 226.496 284.444 290.957 1.00 46.30  ? 103 ILE F C   1 
ATOM   15483 O  O   . ILE F 2 105 ? 226.660 283.335 291.479 1.00 48.91  ? 103 ILE F O   1 
ATOM   15484 C  CB  . ILE F 2 105 ? 228.033 285.361 289.167 1.00 44.39  ? 103 ILE F CB  1 
ATOM   15485 C  CG1 . ILE F 2 105 ? 228.522 285.021 287.759 1.00 43.13  ? 103 ILE F CG1 1 
ATOM   15486 C  CG2 . ILE F 2 105 ? 229.076 284.998 290.209 1.00 45.52  ? 103 ILE F CG2 1 
ATOM   15487 C  CD1 . ILE F 2 105 ? 229.391 286.094 287.145 1.00 38.41  ? 103 ILE F CD1 1 
ATOM   15488 N  N   . PHE F 2 106 ? 226.141 285.514 291.671 1.00 48.75  ? 104 PHE F N   1 
ATOM   15489 C  CA  . PHE F 2 106 ? 225.934 285.413 293.111 1.00 51.69  ? 104 PHE F CA  1 
ATOM   15490 C  C   . PHE F 2 106 ? 224.752 284.511 293.438 1.00 55.69  ? 104 PHE F C   1 
ATOM   15491 O  O   . PHE F 2 106 ? 224.800 283.741 294.403 1.00 61.27  ? 104 PHE F O   1 
ATOM   15492 C  CB  . PHE F 2 106 ? 225.734 286.803 293.712 1.00 53.65  ? 104 PHE F CB  1 
ATOM   15493 C  CG  . PHE F 2 106 ? 225.904 286.848 295.204 1.00 62.32  ? 104 PHE F CG  1 
ATOM   15494 C  CD1 . PHE F 2 106 ? 224.883 286.440 296.044 1.00 63.81  ? 104 PHE F CD1 1 
ATOM   15495 C  CD2 . PHE F 2 106 ? 227.084 287.302 295.766 1.00 63.12  ? 104 PHE F CD2 1 
ATOM   15496 C  CE1 . PHE F 2 106 ? 225.037 286.481 297.415 1.00 67.63  ? 104 PHE F CE1 1 
ATOM   15497 C  CE2 . PHE F 2 106 ? 227.243 287.347 297.135 1.00 67.35  ? 104 PHE F CE2 1 
ATOM   15498 C  CZ  . PHE F 2 106 ? 226.218 286.937 297.961 1.00 71.10  ? 104 PHE F CZ  1 
ATOM   15499 N  N   . GLY F 2 107 ? 223.672 284.599 292.657 1.00 50.57  ? 105 GLY F N   1 
ATOM   15500 C  CA  . GLY F 2 107 ? 222.543 283.714 292.884 1.00 53.24  ? 105 GLY F CA  1 
ATOM   15501 C  C   . GLY F 2 107 ? 222.901 282.255 292.684 1.00 56.40  ? 105 GLY F C   1 
ATOM   15502 O  O   . GLY F 2 107 ? 222.449 281.385 293.432 1.00 62.41  ? 105 GLY F O   1 
ATOM   15503 N  N   . LEU F 2 108 ? 223.717 281.966 291.667 1.00 52.10  ? 106 LEU F N   1 
ATOM   15504 C  CA  . LEU F 2 108 ? 224.157 280.595 291.438 1.00 52.18  ? 106 LEU F CA  1 
ATOM   15505 C  C   . LEU F 2 108 ? 225.096 280.115 292.536 1.00 56.94  ? 106 LEU F C   1 
ATOM   15506 O  O   . LEU F 2 108 ? 225.077 278.932 292.893 1.00 61.41  ? 106 LEU F O   1 
ATOM   15507 C  CB  . LEU F 2 108 ? 224.837 280.488 290.075 1.00 54.99  ? 106 LEU F CB  1 
ATOM   15508 C  CG  . LEU F 2 108 ? 223.900 280.488 288.868 1.00 52.69  ? 106 LEU F CG  1 
ATOM   15509 C  CD1 . LEU F 2 108 ? 224.691 280.621 287.581 1.00 50.70  ? 106 LEU F CD1 1 
ATOM   15510 C  CD2 . LEU F 2 108 ? 223.057 279.229 288.855 1.00 52.38  ? 106 LEU F CD2 1 
ATOM   15511 N  N   . ILE F 2 109 ? 225.931 281.008 293.070 1.00 57.97  ? 107 ILE F N   1 
ATOM   15512 C  CA  . ILE F 2 109 ? 226.832 280.624 294.152 1.00 61.83  ? 107 ILE F CA  1 
ATOM   15513 C  C   . ILE F 2 109 ? 226.054 280.374 295.438 1.00 66.93  ? 107 ILE F C   1 
ATOM   15514 O  O   . ILE F 2 109 ? 226.410 279.495 296.231 1.00 70.04  ? 107 ILE F O   1 
ATOM   15515 C  CB  . ILE F 2 109 ? 227.923 281.689 294.352 1.00 61.01  ? 107 ILE F CB  1 
ATOM   15516 C  CG1 . ILE F 2 109 ? 228.731 281.875 293.069 1.00 54.85  ? 107 ILE F CG1 1 
ATOM   15517 C  CG2 . ILE F 2 109 ? 228.838 281.290 295.494 1.00 61.05  ? 107 ILE F CG2 1 
ATOM   15518 C  CD1 . ILE F 2 109 ? 229.748 282.987 293.155 1.00 47.05  ? 107 ILE F CD1 1 
ATOM   15519 N  N   . ASN F 2 110 ? 225.007 281.163 295.689 1.00 69.80  ? 108 ASN F N   1 
ATOM   15520 C  CA  . ASN F 2 110 ? 224.181 280.920 296.866 1.00 70.99  ? 108 ASN F CA  1 
ATOM   15521 C  C   . ASN F 2 110 ? 223.555 279.535 296.817 1.00 75.20  ? 108 ASN F C   1 
ATOM   15522 O  O   . ASN F 2 110 ? 223.298 278.929 297.864 1.00 81.46  ? 108 ASN F O   1 
ATOM   15523 C  CB  . ASN F 2 110 ? 223.103 281.994 296.993 1.00 71.50  ? 108 ASN F CB  1 
ATOM   15524 C  CG  . ASN F 2 110 ? 222.961 282.507 298.410 1.00 77.71  ? 108 ASN F CG  1 
ATOM   15525 O  OD1 . ASN F 2 110 ? 223.711 282.111 299.300 1.00 79.90  ? 108 ASN F OD1 1 
ATOM   15526 N  ND2 . ASN F 2 110 ? 221.996 283.391 298.627 1.00 78.86  ? 108 ASN F ND2 1 
ATOM   15527 N  N   . SER F 2 111 ? 223.293 279.027 295.619 1.00 70.37  ? 109 SER F N   1 
ATOM   15528 C  CA  . SER F 2 111 ? 222.979 277.620 295.423 1.00 70.82  ? 109 SER F CA  1 
ATOM   15529 C  C   . SER F 2 111 ? 224.291 276.840 295.392 1.00 72.18  ? 109 SER F C   1 
ATOM   15530 O  O   . SER F 2 111 ? 225.354 277.352 295.753 1.00 74.50  ? 109 SER F O   1 
ATOM   15531 C  CB  . SER F 2 111 ? 222.159 277.433 294.151 1.00 69.84  ? 109 SER F CB  1 
ATOM   15532 O  OG  . SER F 2 111 ? 221.290 278.532 293.942 1.00 69.00  ? 109 SER F OG  1 
ATOM   15533 N  N   . ASN F 2 112 ? 224.238 275.582 294.975 1.00 69.09  ? 110 ASN F N   1 
ATOM   15534 C  CA  . ASN F 2 112 ? 225.435 274.775 294.770 1.00 72.66  ? 110 ASN F CA  1 
ATOM   15535 C  C   . ASN F 2 112 ? 225.612 274.442 293.293 1.00 77.65  ? 110 ASN F C   1 
ATOM   15536 O  O   . ASN F 2 112 ? 226.073 273.358 292.931 1.00 84.73  ? 110 ASN F O   1 
ATOM   15537 C  CB  . ASN F 2 112 ? 225.383 273.505 295.613 1.00 79.41  ? 110 ASN F CB  1 
ATOM   15538 C  CG  . ASN F 2 112 ? 225.770 273.751 297.057 1.00 83.72  ? 110 ASN F CG  1 
ATOM   15539 O  OD1 . ASN F 2 112 ? 225.025 274.375 297.813 1.00 84.88  ? 110 ASN F OD1 1 
ATOM   15540 N  ND2 . ASN F 2 112 ? 226.940 273.261 297.450 1.00 79.43  ? 110 ASN F ND2 1 
ATOM   15541 N  N   . SER F 2 113 ? 225.245 275.383 292.424 1.00 71.34  ? 111 SER F N   1 
ATOM   15542 C  CA  . SER F 2 113 ? 225.224 275.165 290.985 1.00 69.69  ? 111 SER F CA  1 
ATOM   15543 C  C   . SER F 2 113 ? 226.388 275.830 290.258 1.00 69.87  ? 111 SER F C   1 
ATOM   15544 O  O   . SER F 2 113 ? 226.429 275.794 289.024 1.00 68.89  ? 111 SER F O   1 
ATOM   15545 C  CB  . SER F 2 113 ? 223.897 275.658 290.405 1.00 62.94  ? 111 SER F CB  1 
ATOM   15546 O  OG  . SER F 2 113 ? 223.476 276.852 291.042 1.00 61.53  ? 111 SER F OG  1 
ATOM   15547 N  N   . LEU F 2 114 ? 227.331 276.430 290.980 1.00 66.33  ? 112 LEU F N   1 
ATOM   15548 C  CA  . LEU F 2 114 ? 228.466 277.085 290.341 1.00 65.39  ? 112 LEU F CA  1 
ATOM   15549 C  C   . LEU F 2 114 ? 229.668 277.046 291.272 1.00 64.87  ? 112 LEU F C   1 
ATOM   15550 O  O   . LEU F 2 114 ? 229.559 277.417 292.444 1.00 66.10  ? 112 LEU F O   1 
ATOM   15551 C  CB  . LEU F 2 114 ? 228.133 278.534 289.967 1.00 59.81  ? 112 LEU F CB  1 
ATOM   15552 C  CG  . LEU F 2 114 ? 229.229 279.295 289.218 1.00 58.69  ? 112 LEU F CG  1 
ATOM   15553 C  CD1 . LEU F 2 114 ? 229.289 278.849 287.769 1.00 52.03  ? 112 LEU F CD1 1 
ATOM   15554 C  CD2 . LEU F 2 114 ? 229.004 280.796 289.308 1.00 54.20  ? 112 LEU F CD2 1 
ATOM   15555 N  N   . ASP F 2 115 ? 230.807 276.605 290.743 1.00 58.41  ? 113 ASP F N   1 
ATOM   15556 C  CA  . ASP F 2 115 ? 232.050 276.504 291.497 1.00 59.00  ? 113 ASP F CA  1 
ATOM   15557 C  C   . ASP F 2 115 ? 233.002 277.599 291.037 1.00 58.86  ? 113 ASP F C   1 
ATOM   15558 O  O   . ASP F 2 115 ? 233.350 277.667 289.854 1.00 59.49  ? 113 ASP F O   1 
ATOM   15559 C  CB  . ASP F 2 115 ? 232.690 275.127 291.317 1.00 63.93  ? 113 ASP F CB  1 
ATOM   15560 C  CG  . ASP F 2 115 ? 231.891 274.021 291.976 1.00 74.84  ? 113 ASP F CG  1 
ATOM   15561 O  OD1 . ASP F 2 115 ? 231.550 274.161 293.169 1.00 73.34  ? 113 ASP F OD1 1 
ATOM   15562 O  OD2 . ASP F 2 115 ? 231.608 273.008 291.302 1.00 76.41  ? 113 ASP F OD2 1 
ATOM   15563 N  N   . VAL F 2 116 ? 233.430 278.442 291.974 1.00 56.10  ? 114 VAL F N   1 
ATOM   15564 C  CA  . VAL F 2 116 ? 234.359 279.526 291.693 1.00 48.71  ? 114 VAL F CA  1 
ATOM   15565 C  C   . VAL F 2 116 ? 235.634 279.286 292.490 1.00 51.01  ? 114 VAL F C   1 
ATOM   15566 O  O   . VAL F 2 116 ? 235.659 278.523 293.458 1.00 57.25  ? 114 VAL F O   1 
ATOM   15567 C  CB  . VAL F 2 116 ? 233.761 280.909 292.018 1.00 47.63  ? 114 VAL F CB  1 
ATOM   15568 C  CG1 . VAL F 2 116 ? 232.488 281.130 291.218 1.00 44.74  ? 114 VAL F CG1 1 
ATOM   15569 C  CG2 . VAL F 2 116 ? 233.489 281.032 293.507 1.00 48.83  ? 114 VAL F CG2 1 
ATOM   15570 N  N   . TYR F 2 117 ? 236.704 279.954 292.069 1.00 50.00  ? 115 TYR F N   1 
ATOM   15571 C  CA  . TYR F 2 117 ? 238.029 279.710 292.615 1.00 51.59  ? 115 TYR F CA  1 
ATOM   15572 C  C   . TYR F 2 117 ? 238.692 281.028 292.985 1.00 50.65  ? 115 TYR F C   1 
ATOM   15573 O  O   . TYR F 2 117 ? 238.439 282.066 292.369 1.00 52.52  ? 115 TYR F O   1 
ATOM   15574 C  CB  . TYR F 2 117 ? 238.895 278.935 291.617 1.00 48.51  ? 115 TYR F CB  1 
ATOM   15575 C  CG  . TYR F 2 117 ? 238.234 277.667 291.127 1.00 55.35  ? 115 TYR F CG  1 
ATOM   15576 C  CD1 . TYR F 2 117 ? 237.373 277.690 290.039 1.00 55.64  ? 115 TYR F CD1 1 
ATOM   15577 C  CD2 . TYR F 2 117 ? 238.458 276.452 291.758 1.00 57.14  ? 115 TYR F CD2 1 
ATOM   15578 C  CE1 . TYR F 2 117 ? 236.760 276.540 289.588 1.00 57.03  ? 115 TYR F CE1 1 
ATOM   15579 C  CE2 . TYR F 2 117 ? 237.848 275.295 291.313 1.00 59.03  ? 115 TYR F CE2 1 
ATOM   15580 C  CZ  . TYR F 2 117 ? 237.000 275.345 290.228 1.00 59.03  ? 115 TYR F CZ  1 
ATOM   15581 O  OH  . TYR F 2 117 ? 236.390 274.197 289.777 1.00 63.55  ? 115 TYR F OH  1 
ATOM   15582 N  N   . GLU F 2 118 ? 239.547 280.971 294.003 1.00 54.01  ? 116 GLU F N   1 
ATOM   15583 C  CA  . GLU F 2 118 ? 240.196 282.171 294.511 1.00 54.73  ? 116 GLU F CA  1 
ATOM   15584 C  C   . GLU F 2 118 ? 241.011 282.853 293.421 1.00 50.33  ? 116 GLU F C   1 
ATOM   15585 O  O   . GLU F 2 118 ? 241.666 282.196 292.607 1.00 47.50  ? 116 GLU F O   1 
ATOM   15586 C  CB  . GLU F 2 118 ? 241.101 281.819 295.693 1.00 60.66  ? 116 GLU F CB  1 
ATOM   15587 C  CG  . GLU F 2 118 ? 240.430 281.910 297.051 1.00 69.86  ? 116 GLU F CG  1 
ATOM   15588 C  CD  . GLU F 2 118 ? 241.306 282.583 298.087 1.00 81.54  ? 116 GLU F CD  1 
ATOM   15589 O  OE1 . GLU F 2 118 ? 242.345 281.997 298.457 1.00 86.92  ? 116 GLU F OE1 1 
ATOM   15590 O  OE2 . GLU F 2 118 ? 240.957 283.696 298.533 1.00 85.13  ? 116 GLU F OE2 1 
ATOM   15591 N  N   . TYR F 2 119 ? 240.968 284.182 293.409 1.00 52.97  ? 117 TYR F N   1 
ATOM   15592 C  CA  . TYR F 2 119 ? 241.809 284.973 292.514 1.00 49.04  ? 117 TYR F CA  1 
ATOM   15593 C  C   . TYR F 2 119 ? 243.191 285.089 293.139 1.00 56.21  ? 117 TYR F C   1 
ATOM   15594 O  O   . TYR F 2 119 ? 243.420 285.914 294.026 1.00 62.45  ? 117 TYR F O   1 
ATOM   15595 C  CB  . TYR F 2 119 ? 241.203 286.348 292.264 1.00 46.12  ? 117 TYR F CB  1 
ATOM   15596 C  CG  . TYR F 2 119 ? 242.103 287.259 291.459 1.00 47.16  ? 117 TYR F CG  1 
ATOM   15597 C  CD1 . TYR F 2 119 ? 242.090 287.232 290.072 1.00 46.88  ? 117 TYR F CD1 1 
ATOM   15598 C  CD2 . TYR F 2 119 ? 242.974 288.138 292.088 1.00 44.73  ? 117 TYR F CD2 1 
ATOM   15599 C  CE1 . TYR F 2 119 ? 242.914 288.060 289.335 1.00 48.49  ? 117 TYR F CE1 1 
ATOM   15600 C  CE2 . TYR F 2 119 ? 243.801 288.966 291.360 1.00 45.95  ? 117 TYR F CE2 1 
ATOM   15601 C  CZ  . TYR F 2 119 ? 243.767 288.925 289.985 1.00 50.20  ? 117 TYR F CZ  1 
ATOM   15602 O  OH  . TYR F 2 119 ? 244.590 289.751 289.255 1.00 48.67  ? 117 TYR F OH  1 
ATOM   15603 N  N   . LEU F 2 120 ? 244.118 284.258 292.679 1.00 57.88  ? 118 LEU F N   1 
ATOM   15604 C  CA  . LEU F 2 120 ? 245.497 284.295 293.136 1.00 59.12  ? 118 LEU F CA  1 
ATOM   15605 C  C   . LEU F 2 120 ? 246.328 285.128 292.172 1.00 63.84  ? 118 LEU F C   1 
ATOM   15606 O  O   . LEU F 2 120 ? 246.186 285.009 290.952 1.00 68.03  ? 118 LEU F O   1 
ATOM   15607 C  CB  . LEU F 2 120 ? 246.075 282.884 293.243 1.00 59.78  ? 118 LEU F CB  1 
ATOM   15608 C  CG  . LEU F 2 120 ? 245.153 281.835 293.862 1.00 59.38  ? 118 LEU F CG  1 
ATOM   15609 C  CD1 . LEU F 2 120 ? 245.521 280.445 293.371 1.00 61.42  ? 118 LEU F CD1 1 
ATOM   15610 C  CD2 . LEU F 2 120 ? 245.206 281.906 295.379 1.00 59.08  ? 118 LEU F CD2 1 
ATOM   15611 N  N   . ASP F 2 121 ? 247.192 285.973 292.723 1.00 64.91  ? 119 ASP F N   1 
ATOM   15612 C  CA  . ASP F 2 121 ? 248.009 286.848 291.895 1.00 71.43  ? 119 ASP F CA  1 
ATOM   15613 C  C   . ASP F 2 121 ? 249.125 286.046 291.235 1.00 70.76  ? 119 ASP F C   1 
ATOM   15614 O  O   . ASP F 2 121 ? 249.921 285.393 291.918 1.00 72.57  ? 119 ASP F O   1 
ATOM   15615 C  CB  . ASP F 2 121 ? 248.581 287.986 292.738 1.00 76.82  ? 119 ASP F CB  1 
ATOM   15616 C  CG  . ASP F 2 121 ? 249.598 287.507 293.754 1.00 83.41  ? 119 ASP F CG  1 
ATOM   15617 O  OD1 . ASP F 2 121 ? 250.780 287.348 293.382 1.00 81.65  ? 119 ASP F OD1 1 
ATOM   15618 O  OD2 . ASP F 2 121 ? 249.217 287.288 294.923 1.00 85.36  ? 119 ASP F OD2 1 
ATOM   15619 N  N   . GLY F 2 122 ? 249.176 286.084 289.901 1.00 62.71  ? 120 GLY F N   1 
ATOM   15620 C  CA  . GLY F 2 122 ? 250.221 285.451 289.127 1.00 57.86  ? 120 GLY F CA  1 
ATOM   15621 C  C   . GLY F 2 122 ? 249.763 284.245 288.330 1.00 57.30  ? 120 GLY F C   1 
ATOM   15622 O  O   . GLY F 2 122 ? 250.306 283.988 287.249 1.00 62.50  ? 120 GLY F O   1 
ATOM   15623 N  N   . PHE F 2 123 ? 248.780 283.503 288.833 1.00 55.16  ? 121 PHE F N   1 
ATOM   15624 C  CA  . PHE F 2 123 ? 248.366 282.271 288.175 1.00 53.80  ? 121 PHE F CA  1 
ATOM   15625 C  C   . PHE F 2 123 ? 246.947 281.923 288.595 1.00 55.41  ? 121 PHE F C   1 
ATOM   15626 O  O   . PHE F 2 123 ? 246.423 282.448 289.580 1.00 56.59  ? 121 PHE F O   1 
ATOM   15627 C  CB  . PHE F 2 123 ? 249.317 281.116 288.504 1.00 57.96  ? 121 PHE F CB  1 
ATOM   15628 C  CG  . PHE F 2 123 ? 249.235 280.654 289.932 1.00 60.88  ? 121 PHE F CG  1 
ATOM   15629 C  CD1 . PHE F 2 123 ? 249.722 281.444 290.959 1.00 58.48  ? 121 PHE F CD1 1 
ATOM   15630 C  CD2 . PHE F 2 123 ? 248.671 279.429 290.246 1.00 60.26  ? 121 PHE F CD2 1 
ATOM   15631 C  CE1 . PHE F 2 123 ? 249.646 281.025 292.270 1.00 59.68  ? 121 PHE F CE1 1 
ATOM   15632 C  CE2 . PHE F 2 123 ? 248.593 279.004 291.557 1.00 64.91  ? 121 PHE F CE2 1 
ATOM   15633 C  CZ  . PHE F 2 123 ? 249.082 279.803 292.570 1.00 65.18  ? 121 PHE F CZ  1 
ATOM   15634 N  N   . GLU F 2 124 ? 246.334 281.027 287.827 1.00 54.48  ? 122 GLU F N   1 
ATOM   15635 C  CA  . GLU F 2 124 ? 244.999 280.518 288.107 1.00 55.52  ? 122 GLU F CA  1 
ATOM   15636 C  C   . GLU F 2 124 ? 245.060 279.001 288.210 1.00 60.56  ? 122 GLU F C   1 
ATOM   15637 O  O   . GLU F 2 124 ? 245.691 278.344 287.375 1.00 63.97  ? 122 GLU F O   1 
ATOM   15638 C  CB  . GLU F 2 124 ? 244.005 280.933 287.018 1.00 52.12  ? 122 GLU F CB  1 
ATOM   15639 C  CG  . GLU F 2 124 ? 243.855 282.434 286.841 1.00 52.06  ? 122 GLU F CG  1 
ATOM   15640 C  CD  . GLU F 2 124 ? 244.918 283.024 285.937 1.00 47.13  ? 122 GLU F CD  1 
ATOM   15641 O  OE1 . GLU F 2 124 ? 245.258 282.381 284.924 1.00 49.38  ? 122 GLU F OE1 1 
ATOM   15642 O  OE2 . GLU F 2 124 ? 245.409 284.132 286.236 1.00 46.36  ? 122 GLU F OE2 1 
ATOM   15643 N  N   . ALA F 2 125 ? 244.408 278.450 289.231 1.00 57.49  ? 123 ALA F N   1 
ATOM   15644 C  CA  . ALA F 2 125 ? 244.333 277.004 289.416 1.00 62.95  ? 123 ALA F CA  1 
ATOM   15645 C  C   . ALA F 2 125 ? 242.908 276.656 289.818 1.00 60.68  ? 123 ALA F C   1 
ATOM   15646 O  O   . ALA F 2 125 ? 242.488 276.955 290.940 1.00 64.38  ? 123 ALA F O   1 
ATOM   15647 C  CB  . ALA F 2 125 ? 245.333 276.524 290.468 1.00 68.88  ? 123 ALA F CB  1 
ATOM   15648 N  N   . PHE F 2 126 ? 242.167 276.027 288.909 1.00 56.62  ? 124 PHE F N   1 
ATOM   15649 C  CA  . PHE F 2 126 ? 240.769 275.678 289.158 1.00 62.69  ? 124 PHE F CA  1 
ATOM   15650 C  C   . PHE F 2 126 ? 240.660 274.248 289.691 1.00 66.96  ? 124 PHE F C   1 
ATOM   15651 O  O   . PHE F 2 126 ? 240.005 273.378 289.119 1.00 66.06  ? 124 PHE F O   1 
ATOM   15652 C  CB  . PHE F 2 126 ? 239.942 275.866 287.891 1.00 59.51  ? 124 PHE F CB  1 
ATOM   15653 C  CG  . PHE F 2 126 ? 240.089 277.224 287.267 1.00 55.87  ? 124 PHE F CG  1 
ATOM   15654 C  CD1 . PHE F 2 126 ? 240.380 278.331 288.044 1.00 54.73  ? 124 PHE F CD1 1 
ATOM   15655 C  CD2 . PHE F 2 126 ? 239.934 277.392 285.903 1.00 52.58  ? 124 PHE F CD2 1 
ATOM   15656 C  CE1 . PHE F 2 126 ? 240.517 279.577 287.472 1.00 51.56  ? 124 PHE F CE1 1 
ATOM   15657 C  CE2 . PHE F 2 126 ? 240.068 278.637 285.327 1.00 50.08  ? 124 PHE F CE2 1 
ATOM   15658 C  CZ  . PHE F 2 126 ? 240.360 279.730 286.112 1.00 53.65  ? 124 PHE F CZ  1 
ATOM   15659 N  N   . THR F 2 127 ? 241.325 274.022 290.818 1.00 72.34  ? 125 THR F N   1 
ATOM   15660 C  CA  . THR F 2 127 ? 241.320 272.736 291.496 1.00 70.39  ? 125 THR F CA  1 
ATOM   15661 C  C   . THR F 2 127 ? 240.610 272.858 292.838 1.00 70.52  ? 125 THR F C   1 
ATOM   15662 O  O   . THR F 2 127 ? 240.411 273.956 293.365 1.00 69.62  ? 125 THR F O   1 
ATOM   15663 C  CB  . THR F 2 127 ? 242.747 272.214 291.700 1.00 71.55  ? 125 THR F CB  1 
ATOM   15664 O  OG1 . THR F 2 127 ? 243.539 273.221 292.342 1.00 71.68  ? 125 THR F OG1 1 
ATOM   15665 C  CG2 . THR F 2 127 ? 243.377 271.857 290.363 1.00 66.57  ? 125 THR F CG2 1 
ATOM   15666 N  N   . ASP F 2 128 ? 240.227 271.705 293.390 1.00 71.68  ? 126 ASP F N   1 
ATOM   15667 C  CA  . ASP F 2 128 ? 239.485 271.692 294.645 1.00 73.72  ? 126 ASP F CA  1 
ATOM   15668 C  C   . ASP F 2 128 ? 240.257 272.349 295.780 1.00 69.54  ? 126 ASP F C   1 
ATOM   15669 O  O   . ASP F 2 128 ? 239.645 272.779 296.764 1.00 65.41  ? 126 ASP F O   1 
ATOM   15670 C  CB  . ASP F 2 128 ? 239.125 270.256 295.026 1.00 77.19  ? 126 ASP F CB  1 
ATOM   15671 C  CG  . ASP F 2 128 ? 238.728 269.419 293.827 1.00 84.82  ? 126 ASP F CG  1 
ATOM   15672 O  OD1 . ASP F 2 128 ? 237.620 269.635 293.292 1.00 85.00  ? 126 ASP F OD1 1 
ATOM   15673 O  OD2 . ASP F 2 128 ? 239.525 268.551 293.416 1.00 84.20  ? 126 ASP F OD2 1 
ATOM   15674 N  N   . GLN F 2 129 ? 241.583 272.435 295.671 1.00 69.06  ? 127 GLN F N   1 
ATOM   15675 C  CA  . GLN F 2 129 ? 242.359 273.108 296.705 1.00 69.64  ? 127 GLN F CA  1 
ATOM   15676 C  C   . GLN F 2 129 ? 242.003 274.586 296.783 1.00 73.13  ? 127 GLN F C   1 
ATOM   15677 O  O   . GLN F 2 129 ? 241.910 275.155 297.877 1.00 70.60  ? 127 GLN F O   1 
ATOM   15678 C  CB  . GLN F 2 129 ? 243.853 272.929 296.441 1.00 69.90  ? 127 GLN F CB  1 
ATOM   15679 C  CG  . GLN F 2 129 ? 244.701 274.106 296.885 1.00 73.63  ? 127 GLN F CG  1 
ATOM   15680 C  CD  . GLN F 2 129 ? 246.159 273.739 297.055 1.00 74.91  ? 127 GLN F CD  1 
ATOM   15681 O  OE1 . GLN F 2 129 ? 246.641 272.776 296.460 1.00 77.45  ? 127 GLN F OE1 1 
ATOM   15682 N  NE2 . GLN F 2 129 ? 246.869 274.502 297.876 1.00 69.42  ? 127 GLN F NE2 1 
ATOM   15683 N  N   . TYR F 2 130 ? 241.802 275.225 295.632 1.00 71.15  ? 128 TYR F N   1 
ATOM   15684 C  CA  . TYR F 2 130 ? 241.501 276.647 295.568 1.00 62.45  ? 128 TYR F CA  1 
ATOM   15685 C  C   . TYR F 2 130 ? 240.014 276.942 295.435 1.00 61.00  ? 128 TYR F C   1 
ATOM   15686 O  O   . TYR F 2 130 ? 239.641 278.111 295.301 1.00 61.70  ? 128 TYR F O   1 
ATOM   15687 C  CB  . TYR F 2 130 ? 242.263 277.290 294.406 1.00 61.81  ? 128 TYR F CB  1 
ATOM   15688 C  CG  . TYR F 2 130 ? 243.753 277.373 294.641 1.00 68.77  ? 128 TYR F CG  1 
ATOM   15689 C  CD1 . TYR F 2 130 ? 244.270 278.172 295.652 1.00 70.82  ? 128 TYR F CD1 1 
ATOM   15690 C  CD2 . TYR F 2 130 ? 244.643 276.650 293.859 1.00 70.11  ? 128 TYR F CD2 1 
ATOM   15691 C  CE1 . TYR F 2 130 ? 245.629 278.252 295.874 1.00 73.12  ? 128 TYR F CE1 1 
ATOM   15692 C  CE2 . TYR F 2 130 ? 246.005 276.724 294.074 1.00 72.07  ? 128 TYR F CE2 1 
ATOM   15693 C  CZ  . TYR F 2 130 ? 246.492 277.527 295.082 1.00 74.11  ? 128 TYR F CZ  1 
ATOM   15694 O  OH  . TYR F 2 130 ? 247.847 277.606 295.302 1.00 74.43  ? 128 TYR F OH  1 
ATOM   15695 N  N   . LYS F 2 131 ? 239.159 275.922 295.468 1.00 63.04  ? 129 LYS F N   1 
ATOM   15696 C  CA  . LYS F 2 131 ? 237.723 276.157 295.405 1.00 59.54  ? 129 LYS F CA  1 
ATOM   15697 C  C   . LYS F 2 131 ? 237.285 277.057 296.552 1.00 66.88  ? 129 LYS F C   1 
ATOM   15698 O  O   . LYS F 2 131 ? 237.693 276.872 297.701 1.00 72.94  ? 129 LYS F O   1 
ATOM   15699 C  CB  . LYS F 2 131 ? 236.965 274.831 295.450 1.00 62.79  ? 129 LYS F CB  1 
ATOM   15700 C  CG  . LYS F 2 131 ? 235.535 274.919 294.947 1.00 65.65  ? 129 LYS F CG  1 
ATOM   15701 C  CD  . LYS F 2 131 ? 234.915 273.543 294.783 1.00 68.66  ? 129 LYS F CD  1 
ATOM   15702 C  CE  . LYS F 2 131 ? 235.925 272.546 294.242 1.00 69.01  ? 129 LYS F CE  1 
ATOM   15703 N  NZ  . LYS F 2 131 ? 235.282 271.258 293.865 1.00 72.97  ? 129 LYS F NZ  1 
ATOM   15704 N  N   . ILE F 2 132 ? 236.446 278.036 296.234 1.00 62.58  ? 130 ILE F N   1 
ATOM   15705 C  CA  . ILE F 2 132 ? 236.059 279.052 297.206 1.00 64.66  ? 130 ILE F CA  1 
ATOM   15706 C  C   . ILE F 2 132 ? 234.902 278.545 298.052 1.00 72.38  ? 130 ILE F C   1 
ATOM   15707 O  O   . ILE F 2 132 ? 233.924 277.989 297.537 1.00 70.50  ? 130 ILE F O   1 
ATOM   15708 C  CB  . ILE F 2 132 ? 235.695 280.369 296.498 1.00 62.66  ? 130 ILE F CB  1 
ATOM   15709 C  CG1 . ILE F 2 132 ? 236.929 281.262 296.370 1.00 62.47  ? 130 ILE F CG1 1 
ATOM   15710 C  CG2 . ILE F 2 132 ? 234.591 281.090 297.251 1.00 67.83  ? 130 ILE F CG2 1 
ATOM   15711 C  CD1 . ILE F 2 132 ? 236.716 282.475 295.499 1.00 59.27  ? 130 ILE F CD1 1 
ATOM   15712 N  N   . LYS F 2 133 ? 235.015 278.735 299.364 1.00 75.49  ? 131 LYS F N   1 
ATOM   15713 C  CA  . LYS F 2 133 ? 233.923 278.464 300.289 1.00 77.53  ? 131 LYS F CA  1 
ATOM   15714 C  C   . LYS F 2 133 ? 233.076 279.724 300.405 1.00 81.52  ? 131 LYS F C   1 
ATOM   15715 O  O   . LYS F 2 133 ? 233.588 280.788 300.770 1.00 84.22  ? 131 LYS F O   1 
ATOM   15716 C  CB  . LYS F 2 133 ? 234.460 278.041 301.656 1.00 79.57  ? 131 LYS F CB  1 
ATOM   15717 C  CG  . LYS F 2 133 ? 235.814 277.356 301.606 1.00 79.84  ? 131 LYS F CG  1 
ATOM   15718 C  CD  . LYS F 2 133 ? 235.673 275.844 301.609 1.00 80.34  ? 131 LYS F CD  1 
ATOM   15719 C  CE  . LYS F 2 133 ? 237.031 275.163 301.586 1.00 75.68  ? 131 LYS F CE  1 
ATOM   15720 N  NZ  . LYS F 2 133 ? 237.832 275.483 302.799 1.00 72.48  ? 131 LYS F NZ  1 
ATOM   15721 N  N   . PHE F 2 134 ? 231.784 279.606 300.094 1.00 79.35  ? 132 PHE F N   1 
ATOM   15722 C  CA  . PHE F 2 134 ? 230.941 280.795 300.026 1.00 79.68  ? 132 PHE F CA  1 
ATOM   15723 C  C   . PHE F 2 134 ? 230.889 281.519 301.363 1.00 84.20  ? 132 PHE F C   1 
ATOM   15724 O  O   . PHE F 2 134 ? 231.010 282.748 301.414 1.00 82.16  ? 132 PHE F O   1 
ATOM   15725 C  CB  . PHE F 2 134 ? 229.534 280.423 299.564 1.00 77.66  ? 132 PHE F CB  1 
ATOM   15726 C  CG  . PHE F 2 134 ? 228.690 281.609 299.203 1.00 77.43  ? 132 PHE F CG  1 
ATOM   15727 C  CD1 . PHE F 2 134 ? 229.230 282.665 298.489 1.00 75.04  ? 132 PHE F CD1 1 
ATOM   15728 C  CD2 . PHE F 2 134 ? 227.360 281.670 299.576 1.00 80.06  ? 132 PHE F CD2 1 
ATOM   15729 C  CE1 . PHE F 2 134 ? 228.461 283.759 298.156 1.00 73.19  ? 132 PHE F CE1 1 
ATOM   15730 C  CE2 . PHE F 2 134 ? 226.586 282.762 299.245 1.00 80.22  ? 132 PHE F CE2 1 
ATOM   15731 C  CZ  . PHE F 2 134 ? 227.137 283.807 298.533 1.00 74.68  ? 132 PHE F CZ  1 
ATOM   15732 N  N   . GLN F 2 135 ? 230.718 280.776 302.459 1.00 89.07  ? 133 GLN F N   1 
ATOM   15733 C  CA  . GLN F 2 135 ? 230.637 281.407 303.773 1.00 87.52  ? 133 GLN F CA  1 
ATOM   15734 C  C   . GLN F 2 135 ? 231.856 282.282 304.034 1.00 84.24  ? 133 GLN F C   1 
ATOM   15735 O  O   . GLN F 2 135 ? 231.734 283.406 304.533 1.00 82.24  ? 133 GLN F O   1 
ATOM   15736 C  CB  . GLN F 2 135 ? 230.494 280.343 304.863 1.00 91.39  ? 133 GLN F CB  1 
ATOM   15737 C  CG  . GLN F 2 135 ? 231.284 280.647 306.126 1.00 90.42  ? 133 GLN F CG  1 
ATOM   15738 C  CD  . GLN F 2 135 ? 230.586 281.653 307.022 1.00 89.18  ? 133 GLN F CD  1 
ATOM   15739 O  OE1 . GLN F 2 135 ? 229.362 281.771 307.005 1.00 89.20  ? 133 GLN F OE1 1 
ATOM   15740 N  NE2 . GLN F 2 135 ? 231.366 282.388 307.805 1.00 85.32  ? 133 GLN F NE2 1 
ATOM   15741 N  N   . GLU F 2 136 ? 233.042 281.782 303.704 1.00 86.55  ? 134 GLU F N   1 
ATOM   15742 C  CA  . GLU F 2 136 ? 234.266 282.566 303.851 1.00 89.60  ? 134 GLU F CA  1 
ATOM   15743 C  C   . GLU F 2 136 ? 234.556 283.358 302.574 1.00 87.69  ? 134 GLU F C   1 
ATOM   15744 O  O   . GLU F 2 136 ? 235.654 283.344 302.021 1.00 88.57  ? 134 GLU F O   1 
ATOM   15745 C  CB  . GLU F 2 136 ? 235.422 281.642 304.229 1.00 91.13  ? 134 GLU F CB  1 
ATOM   15746 C  CG  . GLU F 2 136 ? 236.833 282.207 304.078 1.00 91.29  ? 134 GLU F CG  1 
ATOM   15747 C  CD  . GLU F 2 136 ? 236.945 283.661 304.498 1.00 93.29  ? 134 GLU F CD  1 
ATOM   15748 O  OE1 . GLU F 2 136 ? 236.185 284.089 305.391 1.00 95.27  ? 134 GLU F OE1 1 
ATOM   15749 O  OE2 . GLU F 2 136 ? 237.793 284.377 303.926 1.00 90.70  ? 134 GLU F OE2 1 
ATOM   15750 N  N   . PHE F 2 137 ? 233.528 284.042 302.077 1.00 84.00  ? 135 PHE F N   1 
ATOM   15751 C  CA  . PHE F 2 137 ? 233.711 285.034 301.026 1.00 81.30  ? 135 PHE F CA  1 
ATOM   15752 C  C   . PHE F 2 137 ? 232.957 286.308 301.381 1.00 80.98  ? 135 PHE F C   1 
ATOM   15753 O  O   . PHE F 2 137 ? 233.373 287.411 301.012 1.00 80.39  ? 135 PHE F O   1 
ATOM   15754 C  CB  . PHE F 2 137 ? 233.244 284.495 299.672 1.00 77.02  ? 135 PHE F CB  1 
ATOM   15755 C  CG  . PHE F 2 137 ? 233.069 285.559 298.629 1.00 72.47  ? 135 PHE F CG  1 
ATOM   15756 C  CD1 . PHE F 2 137 ? 234.149 285.997 297.883 1.00 71.69  ? 135 PHE F CD1 1 
ATOM   15757 C  CD2 . PHE F 2 137 ? 231.828 286.127 298.399 1.00 74.10  ? 135 PHE F CD2 1 
ATOM   15758 C  CE1 . PHE F 2 137 ? 233.993 286.979 296.925 1.00 69.86  ? 135 PHE F CE1 1 
ATOM   15759 C  CE2 . PHE F 2 137 ? 231.667 287.109 297.445 1.00 71.65  ? 135 PHE F CE2 1 
ATOM   15760 C  CZ  . PHE F 2 137 ? 232.751 287.536 296.706 1.00 67.91  ? 135 PHE F CZ  1 
ATOM   15761 N  N   . LEU F 2 138 ? 231.846 286.161 302.105 1.00 78.74  ? 136 LEU F N   1 
ATOM   15762 C  CA  . LEU F 2 138 ? 231.001 287.307 302.421 1.00 80.57  ? 136 LEU F CA  1 
ATOM   15763 C  C   . LEU F 2 138 ? 231.600 288.150 303.538 1.00 83.78  ? 136 LEU F C   1 
ATOM   15764 O  O   . LEU F 2 138 ? 231.783 289.362 303.379 1.00 84.24  ? 136 LEU F O   1 
ATOM   15765 C  CB  . LEU F 2 138 ? 229.594 286.837 302.796 1.00 80.48  ? 136 LEU F CB  1 
ATOM   15766 C  CG  . LEU F 2 138 ? 228.766 286.211 301.673 1.00 74.89  ? 136 LEU F CG  1 
ATOM   15767 C  CD1 . LEU F 2 138 ? 228.983 284.714 301.623 1.00 77.78  ? 136 LEU F CD1 1 
ATOM   15768 C  CD2 . LEU F 2 138 ? 227.291 286.533 301.847 1.00 79.81  ? 136 LEU F CD2 1 
ATOM   15769 N  N   . ASP F 2 139 ? 231.909 287.529 304.680 1.00 82.62  ? 137 ASP F N   1 
ATOM   15770 C  CA  . ASP F 2 139 ? 232.529 288.279 305.766 1.00 82.66  ? 137 ASP F CA  1 
ATOM   15771 C  C   . ASP F 2 139 ? 233.893 288.817 305.358 1.00 80.90  ? 137 ASP F C   1 
ATOM   15772 O  O   . ASP F 2 139 ? 234.332 289.852 305.873 1.00 78.80  ? 137 ASP F O   1 
ATOM   15773 C  CB  . ASP F 2 139 ? 232.648 287.407 307.018 1.00 85.16  ? 137 ASP F CB  1 
ATOM   15774 C  CG  . ASP F 2 139 ? 233.182 286.023 306.719 1.00 90.45  ? 137 ASP F CG  1 
ATOM   15775 O  OD1 . ASP F 2 139 ? 232.372 285.132 306.389 1.00 93.79  ? 137 ASP F OD1 1 
ATOM   15776 O  OD2 . ASP F 2 139 ? 234.411 285.824 306.816 1.00 90.39  ? 137 ASP F OD2 1 
ATOM   15777 N  N   . ARG F 2 140 ? 234.574 288.136 304.436 1.00 82.16  ? 138 ARG F N   1 
ATOM   15778 C  CA  . ARG F 2 140 ? 235.842 288.646 303.928 1.00 81.56  ? 138 ARG F CA  1 
ATOM   15779 C  C   . ARG F 2 140 ? 235.659 289.997 303.248 1.00 79.58  ? 138 ARG F C   1 
ATOM   15780 O  O   . ARG F 2 140 ? 236.465 290.913 303.443 1.00 79.74  ? 138 ARG F O   1 
ATOM   15781 C  CB  . ARG F 2 140 ? 236.463 287.641 302.960 1.00 78.71  ? 138 ARG F CB  1 
ATOM   15782 C  CG  . ARG F 2 140 ? 237.877 287.987 302.538 1.00 78.48  ? 138 ARG F CG  1 
ATOM   15783 C  CD  . ARG F 2 140 ? 238.146 287.541 301.111 1.00 84.38  ? 138 ARG F CD  1 
ATOM   15784 N  NE  . ARG F 2 140 ? 239.035 288.462 300.412 1.00 86.58  ? 138 ARG F NE  1 
ATOM   15785 C  CZ  . ARG F 2 140 ? 240.093 288.092 299.704 1.00 82.21  ? 138 ARG F CZ  1 
ATOM   15786 N  NH1 . ARG F 2 140 ? 240.427 286.819 299.574 1.00 77.99  ? 138 ARG F NH1 1 
ATOM   15787 N  NH2 . ARG F 2 140 ? 240.834 289.023 299.111 1.00 79.63  ? 138 ARG F NH2 1 
ATOM   15788 N  N   . PHE F 2 141 ? 234.604 290.140 302.448 1.00 80.58  ? 139 PHE F N   1 
ATOM   15789 C  CA  . PHE F 2 141 ? 234.342 291.365 301.706 1.00 80.95  ? 139 PHE F CA  1 
ATOM   15790 C  C   . PHE F 2 141 ? 233.256 292.221 302.345 1.00 79.02  ? 139 PHE F C   1 
ATOM   15791 O  O   . PHE F 2 141 ? 232.732 293.129 301.692 1.00 77.79  ? 139 PHE F O   1 
ATOM   15792 C  CB  . PHE F 2 141 ? 233.972 291.035 300.259 1.00 78.34  ? 139 PHE F CB  1 
ATOM   15793 C  CG  . PHE F 2 141 ? 235.126 290.535 299.439 1.00 76.49  ? 139 PHE F CG  1 
ATOM   15794 C  CD1 . PHE F 2 141 ? 236.001 291.423 298.837 1.00 76.67  ? 139 PHE F CD1 1 
ATOM   15795 C  CD2 . PHE F 2 141 ? 235.340 289.178 299.273 1.00 75.40  ? 139 PHE F CD2 1 
ATOM   15796 C  CE1 . PHE F 2 141 ? 237.066 290.966 298.083 1.00 77.33  ? 139 PHE F CE1 1 
ATOM   15797 C  CE2 . PHE F 2 141 ? 236.402 288.715 298.521 1.00 70.87  ? 139 PHE F CE2 1 
ATOM   15798 C  CZ  . PHE F 2 141 ? 237.266 289.610 297.925 1.00 71.22  ? 139 PHE F CZ  1 
ATOM   15799 N  N   . GLY F 2 142 ? 232.908 291.954 303.601 1.00 78.67  ? 140 GLY F N   1 
ATOM   15800 C  CA  . GLY F 2 142 ? 231.958 292.780 304.319 1.00 78.97  ? 140 GLY F CA  1 
ATOM   15801 C  C   . GLY F 2 142 ? 230.557 292.774 303.744 1.00 81.01  ? 140 GLY F C   1 
ATOM   15802 O  O   . GLY F 2 142 ? 229.944 293.833 303.583 1.00 84.11  ? 140 GLY F O   1 
ATOM   15803 N  N   . ILE F 2 143 ? 230.039 291.592 303.428 1.00 79.83  ? 141 ILE F N   1 
ATOM   15804 C  CA  . ILE F 2 143 ? 228.680 291.437 302.924 1.00 81.05  ? 141 ILE F CA  1 
ATOM   15805 C  C   . ILE F 2 143 ? 227.831 290.881 304.059 1.00 84.03  ? 141 ILE F C   1 
ATOM   15806 O  O   . ILE F 2 143 ? 228.013 289.735 304.482 1.00 85.35  ? 141 ILE F O   1 
ATOM   15807 C  CB  . ILE F 2 143 ? 228.629 290.527 301.690 1.00 77.62  ? 141 ILE F CB  1 
ATOM   15808 C  CG1 . ILE F 2 143 ? 229.316 291.200 300.503 1.00 71.62  ? 141 ILE F CG1 1 
ATOM   15809 C  CG2 . ILE F 2 143 ? 227.191 290.194 301.338 1.00 76.19  ? 141 ILE F CG2 1 
ATOM   15810 C  CD1 . ILE F 2 143 ? 230.217 290.276 299.723 1.00 66.01  ? 141 ILE F CD1 1 
ATOM   15811 N  N   . TYR F 2 144 ? 226.900 291.691 304.555 1.00 85.40  ? 142 TYR F N   1 
ATOM   15812 C  CA  . TYR F 2 144 ? 226.055 291.270 305.663 1.00 90.69  ? 142 TYR F CA  1 
ATOM   15813 C  C   . TYR F 2 144 ? 225.069 290.208 305.192 1.00 91.99  ? 142 TYR F C   1 
ATOM   15814 O  O   . TYR F 2 144 ? 224.390 290.383 304.176 1.00 90.58  ? 142 TYR F O   1 
ATOM   15815 C  CB  . TYR F 2 144 ? 225.310 292.472 306.244 1.00 91.67  ? 142 TYR F CB  1 
ATOM   15816 C  CG  . TYR F 2 144 ? 224.311 292.117 307.322 1.00 96.38  ? 142 TYR F CG  1 
ATOM   15817 C  CD1 . TYR F 2 144 ? 224.727 291.540 308.514 1.00 97.23  ? 142 TYR F CD1 1 
ATOM   15818 C  CD2 . TYR F 2 144 ? 222.956 292.361 307.150 1.00 93.99  ? 142 TYR F CD2 1 
ATOM   15819 C  CE1 . TYR F 2 144 ? 223.823 291.215 309.504 1.00 99.50  ? 142 TYR F CE1 1 
ATOM   15820 C  CE2 . TYR F 2 144 ? 222.042 292.038 308.136 1.00 97.23  ? 142 TYR F CE2 1 
ATOM   15821 C  CZ  . TYR F 2 144 ? 222.481 291.465 309.310 1.00 102.14 ? 142 TYR F CZ  1 
ATOM   15822 O  OH  . TYR F 2 144 ? 221.576 291.142 310.295 1.00 105.38 ? 142 TYR F OH  1 
ATOM   15823 N  N   . TYR F 2 145 ? 224.988 289.105 305.933 1.00 91.57  ? 143 TYR F N   1 
ATOM   15824 C  CA  . TYR F 2 145 ? 224.120 287.997 305.569 1.00 93.03  ? 143 TYR F CA  1 
ATOM   15825 C  C   . TYR F 2 145 ? 223.405 287.477 306.808 1.00 98.45  ? 143 TYR F C   1 
ATOM   15826 O  O   . TYR F 2 145 ? 223.808 287.741 307.943 1.00 97.09  ? 143 TYR F O   1 
ATOM   15827 C  CB  . TYR F 2 145 ? 224.903 286.867 304.883 1.00 89.71  ? 143 TYR F CB  1 
ATOM   15828 C  CG  . TYR F 2 145 ? 225.914 286.174 305.769 1.00 89.85  ? 143 TYR F CG  1 
ATOM   15829 C  CD1 . TYR F 2 145 ? 225.532 285.156 306.631 1.00 91.81  ? 143 TYR F CD1 1 
ATOM   15830 C  CD2 . TYR F 2 145 ? 227.254 286.532 305.733 1.00 88.06  ? 143 TYR F CD2 1 
ATOM   15831 C  CE1 . TYR F 2 145 ? 226.455 284.521 307.438 1.00 89.16  ? 143 TYR F CE1 1 
ATOM   15832 C  CE2 . TYR F 2 145 ? 228.182 285.902 306.535 1.00 86.59  ? 143 TYR F CE2 1 
ATOM   15833 C  CZ  . TYR F 2 145 ? 227.777 284.898 307.385 1.00 89.18  ? 143 TYR F CZ  1 
ATOM   15834 O  OH  . TYR F 2 145 ? 228.700 284.266 308.186 1.00 94.05  ? 143 TYR F OH  1 
ATOM   15835 N  N   . GLN F 2 146 ? 222.331 286.732 306.570 1.00 100.38 ? 144 GLN F N   1 
ATOM   15836 C  CA  . GLN F 2 146 ? 221.507 286.158 307.619 1.00 99.93  ? 144 GLN F CA  1 
ATOM   15837 C  C   . GLN F 2 146 ? 221.322 284.670 307.371 1.00 101.63 ? 144 GLN F C   1 
ATOM   15838 O  O   . GLN F 2 146 ? 221.430 284.208 306.232 1.00 98.92  ? 144 GLN F O   1 
ATOM   15839 C  CB  . GLN F 2 146 ? 220.134 286.842 307.681 1.00 100.49 ? 144 GLN F CB  1 
ATOM   15840 C  CG  . GLN F 2 146 ? 220.148 288.296 307.244 1.00 98.62  ? 144 GLN F CG  1 
ATOM   15841 C  CD  . GLN F 2 146 ? 219.086 289.124 307.941 1.00 101.70 ? 144 GLN F CD  1 
ATOM   15842 O  OE1 . GLN F 2 146 ? 219.397 290.020 308.724 1.00 98.60  ? 144 GLN F OE1 1 
ATOM   15843 N  NE2 . GLN F 2 146 ? 217.824 288.827 307.656 1.00 101.03 ? 144 GLN F NE2 1 
ATOM   15844 N  N   . PRO F 2 147 ? 221.050 283.896 308.421 1.00 106.17 ? 145 PRO F N   1 
ATOM   15845 C  CA  . PRO F 2 147 ? 220.815 282.461 308.231 1.00 106.88 ? 145 PRO F CA  1 
ATOM   15846 C  C   . PRO F 2 147 ? 219.644 282.215 307.293 1.00 106.36 ? 145 PRO F C   1 
ATOM   15847 O  O   . PRO F 2 147 ? 218.666 282.966 307.271 1.00 105.47 ? 145 PRO F O   1 
ATOM   15848 C  CB  . PRO F 2 147 ? 220.516 281.960 309.649 1.00 107.41 ? 145 PRO F CB  1 
ATOM   15849 C  CG  . PRO F 2 147 ? 221.178 282.956 310.545 1.00 102.54 ? 145 PRO F CG  1 
ATOM   15850 C  CD  . PRO F 2 147 ? 221.056 284.277 309.843 1.00 102.16 ? 145 PRO F CD  1 
ATOM   15851 N  N   . SER F 2 148 ? 219.755 281.148 306.508 1.00 105.39 ? 146 SER F N   1 
ATOM   15852 C  CA  . SER F 2 148 ? 218.761 280.852 305.487 1.00 109.49 ? 146 SER F CA  1 
ATOM   15853 C  C   . SER F 2 148 ? 217.577 280.101 306.081 1.00 115.38 ? 146 SER F C   1 
ATOM   15854 O  O   . SER F 2 148 ? 217.734 279.274 306.984 1.00 113.88 ? 146 SER F O   1 
ATOM   15855 C  CB  . SER F 2 148 ? 219.383 280.028 304.360 1.00 105.63 ? 146 SER F CB  1 
ATOM   15856 O  OG  . SER F 2 148 ? 220.108 278.926 304.877 1.00 106.55 ? 146 SER F OG  1 
ATOM   15857 N  N   . THR F 2 149 ? 216.384 280.398 305.566 1.00 119.68 ? 147 THR F N   1 
ATOM   15858 C  CA  . THR F 2 149 ? 215.186 279.670 305.961 1.00 123.46 ? 147 THR F CA  1 
ATOM   15859 C  C   . THR F 2 149 ? 215.004 278.378 305.178 1.00 124.45 ? 147 THR F C   1 
ATOM   15860 O  O   . THR F 2 149 ? 214.086 277.610 305.484 1.00 124.50 ? 147 THR F O   1 
ATOM   15861 C  CB  . THR F 2 149 ? 213.945 280.551 305.786 1.00 124.62 ? 147 THR F CB  1 
ATOM   15862 O  OG1 . THR F 2 149 ? 213.798 280.905 304.405 1.00 125.51 ? 147 THR F OG1 1 
ATOM   15863 C  CG2 . THR F 2 149 ? 214.071 281.818 306.620 1.00 118.53 ? 147 THR F CG2 1 
ATOM   15864 N  N   . ASN F 2 150 ? 215.849 278.126 304.181 1.00 123.07 ? 148 ASN F N   1 
ATOM   15865 C  CA  . ASN F 2 150 ? 215.831 276.878 303.431 1.00 121.37 ? 148 ASN F CA  1 
ATOM   15866 C  C   . ASN F 2 150 ? 217.262 276.489 303.102 1.00 118.20 ? 148 ASN F C   1 
ATOM   15867 O  O   . ASN F 2 150 ? 218.017 277.300 302.558 1.00 116.51 ? 148 ASN F O   1 
ATOM   15868 C  CB  . ASN F 2 150 ? 215.007 277.010 302.145 1.00 117.79 ? 148 ASN F CB  1 
ATOM   15869 C  CG  . ASN F 2 150 ? 214.487 275.676 301.647 1.00 119.76 ? 148 ASN F CG  1 
ATOM   15870 O  OD1 . ASN F 2 150 ? 214.708 274.639 302.273 1.00 121.96 ? 148 ASN F OD1 1 
ATOM   15871 N  ND2 . ASN F 2 150 ? 213.795 275.696 300.514 1.00 116.43 ? 148 ASN F ND2 1 
ATOM   15872 N  N   . LYS F 2 151 ? 217.633 275.253 303.433 1.00 118.29 ? 149 LYS F N   1 
ATOM   15873 C  CA  . LYS F 2 151 ? 218.972 274.762 303.139 1.00 119.15 ? 149 LYS F CA  1 
ATOM   15874 C  C   . LYS F 2 151 ? 219.148 274.361 301.682 1.00 117.36 ? 149 LYS F C   1 
ATOM   15875 O  O   . LYS F 2 151 ? 220.277 274.082 301.266 1.00 114.85 ? 149 LYS F O   1 
ATOM   15876 C  CB  . LYS F 2 151 ? 219.311 273.572 304.041 1.00 120.92 ? 149 LYS F CB  1 
ATOM   15877 C  CG  . LYS F 2 151 ? 219.828 273.959 305.419 1.00 117.23 ? 149 LYS F CG  1 
ATOM   15878 C  CD  . LYS F 2 151 ? 218.773 274.706 306.216 1.00 120.85 ? 149 LYS F CD  1 
ATOM   15879 C  CE  . LYS F 2 151 ? 217.446 273.965 306.205 1.00 122.39 ? 149 LYS F CE  1 
ATOM   15880 N  NZ  . LYS F 2 151 ? 216.295 274.887 306.411 1.00 120.80 ? 149 LYS F NZ  1 
ATOM   15881 N  N   . ASN F 2 152 ? 218.071 274.327 300.903 1.00 117.31 ? 150 ASN F N   1 
ATOM   15882 C  CA  . ASN F 2 152 ? 218.123 273.930 299.502 1.00 115.81 ? 150 ASN F CA  1 
ATOM   15883 C  C   . ASN F 2 152 ? 218.139 275.177 298.628 1.00 109.46 ? 150 ASN F C   1 
ATOM   15884 O  O   . ASN F 2 152 ? 217.219 276.000 298.695 1.00 107.38 ? 150 ASN F O   1 
ATOM   15885 C  CB  . ASN F 2 152 ? 216.935 273.038 299.144 1.00 117.34 ? 150 ASN F CB  1 
ATOM   15886 C  CG  . ASN F 2 152 ? 216.660 271.983 300.197 1.00 118.19 ? 150 ASN F CG  1 
ATOM   15887 O  OD1 . ASN F 2 152 ? 217.583 271.441 300.806 1.00 120.23 ? 150 ASN F OD1 1 
ATOM   15888 N  ND2 . ASN F 2 152 ? 215.385 271.686 300.417 1.00 112.96 ? 150 ASN F ND2 1 
ATOM   15889 N  N   . ALA F 2 153 ? 219.180 275.311 297.809 1.00 108.74 ? 151 ALA F N   1 
ATOM   15890 C  CA  . ALA F 2 153 ? 219.334 276.413 296.866 1.00 103.33 ? 151 ALA F CA  1 
ATOM   15891 C  C   . ALA F 2 153 ? 219.560 277.754 297.553 1.00 99.29  ? 151 ALA F C   1 
ATOM   15892 O  O   . ALA F 2 153 ? 219.427 278.805 296.916 1.00 97.37  ? 151 ALA F O   1 
ATOM   15893 C  CB  . ALA F 2 153 ? 218.127 276.509 295.927 1.00 102.68 ? 151 ALA F CB  1 
ATOM   15894 N  N   . GLU F 2 154 ? 219.900 277.748 298.843 1.00 97.34  ? 152 GLU F N   1 
ATOM   15895 C  CA  . GLU F 2 154 ? 220.241 278.987 299.543 1.00 93.04  ? 152 GLU F CA  1 
ATOM   15896 C  C   . GLU F 2 154 ? 221.141 278.622 300.723 1.00 94.69  ? 152 GLU F C   1 
ATOM   15897 O  O   . GLU F 2 154 ? 220.649 278.163 301.757 1.00 100.35 ? 152 GLU F O   1 
ATOM   15898 C  CB  . GLU F 2 154 ? 218.994 279.726 299.998 1.00 93.28  ? 152 GLU F CB  1 
ATOM   15899 C  CG  . GLU F 2 154 ? 219.153 281.237 300.028 1.00 90.48  ? 152 GLU F CG  1 
ATOM   15900 C  CD  . GLU F 2 154 ? 218.807 281.890 298.705 1.00 96.14  ? 152 GLU F CD  1 
ATOM   15901 O  OE1 . GLU F 2 154 ? 219.709 282.014 297.848 1.00 96.11  ? 152 GLU F OE1 1 
ATOM   15902 O  OE2 . GLU F 2 154 ? 217.636 282.285 298.522 1.00 94.78  ? 152 GLU F OE2 1 
ATOM   15903 N  N   . LEU F 2 155 ? 222.448 278.833 300.557 1.00 87.66  ? 153 LEU F N   1 
ATOM   15904 C  CA  . LEU F 2 155 ? 223.377 278.565 301.649 1.00 89.28  ? 153 LEU F CA  1 
ATOM   15905 C  C   . LEU F 2 155 ? 223.270 279.630 302.731 1.00 91.95  ? 153 LEU F C   1 
ATOM   15906 O  O   . LEU F 2 155 ? 223.424 279.334 303.922 1.00 91.89  ? 153 LEU F O   1 
ATOM   15907 C  CB  . LEU F 2 155 ? 224.806 278.477 301.114 1.00 87.15  ? 153 LEU F CB  1 
ATOM   15908 C  CG  . LEU F 2 155 ? 225.052 277.402 300.053 1.00 85.66  ? 153 LEU F CG  1 
ATOM   15909 C  CD1 . LEU F 2 155 ? 226.541 277.153 299.870 1.00 79.90  ? 153 LEU F CD1 1 
ATOM   15910 C  CD2 . LEU F 2 155 ? 224.328 276.114 300.411 1.00 85.72  ? 153 LEU F CD2 1 
ATOM   15911 N  N   . PHE F 2 156 ? 223.014 280.875 302.337 1.00 90.40  ? 154 PHE F N   1 
ATOM   15912 C  CA  . PHE F 2 156 ? 222.789 281.967 303.270 1.00 89.81  ? 154 PHE F CA  1 
ATOM   15913 C  C   . PHE F 2 156 ? 221.693 282.860 302.705 1.00 91.31  ? 154 PHE F C   1 
ATOM   15914 O  O   . PHE F 2 156 ? 221.229 282.669 301.577 1.00 92.44  ? 154 PHE F O   1 
ATOM   15915 C  CB  . PHE F 2 156 ? 224.074 282.766 303.528 1.00 89.19  ? 154 PHE F CB  1 
ATOM   15916 C  CG  . PHE F 2 156 ? 225.183 281.958 304.142 1.00 93.11  ? 154 PHE F CG  1 
ATOM   15917 C  CD1 . PHE F 2 156 ? 225.953 281.106 303.368 1.00 93.07  ? 154 PHE F CD1 1 
ATOM   15918 C  CD2 . PHE F 2 156 ? 225.449 282.046 305.497 1.00 91.60  ? 154 PHE F CD2 1 
ATOM   15919 C  CE1 . PHE F 2 156 ? 226.971 280.363 303.934 1.00 90.65  ? 154 PHE F CE1 1 
ATOM   15920 C  CE2 . PHE F 2 156 ? 226.464 281.306 306.068 1.00 90.43  ? 154 PHE F CE2 1 
ATOM   15921 C  CZ  . PHE F 2 156 ? 227.226 280.463 305.286 1.00 90.36  ? 154 PHE F CZ  1 
ATOM   15922 N  N   . LYS F 2 157 ? 221.272 283.839 303.499 1.00 95.59  ? 155 LYS F N   1 
ATOM   15923 C  CA  . LYS F 2 157 ? 220.266 284.814 303.092 1.00 93.68  ? 155 LYS F CA  1 
ATOM   15924 C  C   . LYS F 2 157 ? 220.951 286.167 302.944 1.00 92.59  ? 155 LYS F C   1 
ATOM   15925 O  O   . LYS F 2 157 ? 221.416 286.745 303.931 1.00 94.22  ? 155 LYS F O   1 
ATOM   15926 C  CB  . LYS F 2 157 ? 219.126 284.884 304.105 1.00 95.38  ? 155 LYS F CB  1 
ATOM   15927 C  CG  . LYS F 2 157 ? 218.305 286.160 304.022 1.00 96.76  ? 155 LYS F CG  1 
ATOM   15928 C  CD  . LYS F 2 157 ? 217.186 286.167 305.048 1.00 100.95 ? 155 LYS F CD  1 
ATOM   15929 C  CE  . LYS F 2 157 ? 215.865 285.755 304.420 1.00 103.79 ? 155 LYS F CE  1 
ATOM   15930 N  NZ  . LYS F 2 157 ? 215.601 286.487 303.151 1.00 102.13 ? 155 LYS F NZ  1 
ATOM   15931 N  N   . VAL F 2 158 ? 221.009 286.670 301.715 1.00 87.68  ? 156 VAL F N   1 
ATOM   15932 C  CA  . VAL F 2 158 ? 221.649 287.942 301.410 1.00 84.65  ? 156 VAL F CA  1 
ATOM   15933 C  C   . VAL F 2 158 ? 220.630 288.843 300.730 1.00 84.63  ? 156 VAL F C   1 
ATOM   15934 O  O   . VAL F 2 158 ? 219.953 288.420 299.785 1.00 86.22  ? 156 VAL F O   1 
ATOM   15935 C  CB  . VAL F 2 158 ? 222.893 287.754 300.523 1.00 80.59  ? 156 VAL F CB  1 
ATOM   15936 C  CG1 . VAL F 2 158 ? 223.761 288.999 300.563 1.00 78.10  ? 156 VAL F CG1 1 
ATOM   15937 C  CG2 . VAL F 2 158 ? 223.679 286.530 300.968 1.00 79.50  ? 156 VAL F CG2 1 
ATOM   15938 N  N   . ALA F 2 159 ? 220.520 290.076 301.213 1.00 84.11  ? 157 ALA F N   1 
ATOM   15939 C  CA  . ALA F 2 159 ? 219.627 291.049 300.607 1.00 82.85  ? 157 ALA F CA  1 
ATOM   15940 C  C   . ALA F 2 159 ? 220.272 291.668 299.374 1.00 83.37  ? 157 ALA F C   1 
ATOM   15941 O  O   . ALA F 2 159 ? 221.497 291.782 299.277 1.00 82.92  ? 157 ALA F O   1 
ATOM   15942 C  CB  . ALA F 2 159 ? 219.259 292.143 301.610 1.00 80.19  ? 157 ALA F CB  1 
ATOM   15943 N  N   . ASP F 2 160 ? 219.427 292.069 298.421 1.00 81.82  ? 158 ASP F N   1 
ATOM   15944 C  CA  . ASP F 2 160 ? 219.936 292.671 297.194 1.00 81.26  ? 158 ASP F CA  1 
ATOM   15945 C  C   . ASP F 2 160 ? 220.782 293.902 297.483 1.00 78.14  ? 158 ASP F C   1 
ATOM   15946 O  O   . ASP F 2 160 ? 221.741 294.181 296.754 1.00 77.79  ? 158 ASP F O   1 
ATOM   15947 C  CB  . ASP F 2 160 ? 218.776 293.028 296.265 1.00 86.41  ? 158 ASP F CB  1 
ATOM   15948 C  CG  . ASP F 2 160 ? 218.212 291.818 295.548 1.00 87.97  ? 158 ASP F CG  1 
ATOM   15949 O  OD1 . ASP F 2 160 ? 218.238 290.713 296.132 1.00 90.17  ? 158 ASP F OD1 1 
ATOM   15950 O  OD2 . ASP F 2 160 ? 217.741 291.971 294.402 1.00 78.86  ? 158 ASP F OD2 1 
ATOM   15951 N  N   . SER F 2 161 ? 220.447 294.652 298.535 1.00 80.05  ? 159 SER F N   1 
ATOM   15952 C  CA  . SER F 2 161 ? 221.253 295.812 298.896 1.00 81.24  ? 159 SER F CA  1 
ATOM   15953 C  C   . SER F 2 161 ? 222.655 295.405 299.328 1.00 81.96  ? 159 SER F C   1 
ATOM   15954 O  O   . SER F 2 161 ? 223.617 296.144 299.093 1.00 78.23  ? 159 SER F O   1 
ATOM   15955 C  CB  . SER F 2 161 ? 220.563 296.607 300.005 1.00 85.92  ? 159 SER F CB  1 
ATOM   15956 O  OG  . SER F 2 161 ? 220.155 295.758 301.063 1.00 86.07  ? 159 SER F OG  1 
ATOM   15957 N  N   . ASP F 2 162 ? 222.792 294.237 299.959 1.00 82.38  ? 160 ASP F N   1 
ATOM   15958 C  CA  . ASP F 2 162 ? 224.106 293.764 300.377 1.00 78.71  ? 160 ASP F CA  1 
ATOM   15959 C  C   . ASP F 2 162 ? 224.921 293.227 299.209 1.00 75.09  ? 160 ASP F C   1 
ATOM   15960 O  O   . ASP F 2 162 ? 226.149 293.366 299.200 1.00 74.19  ? 160 ASP F O   1 
ATOM   15961 C  CB  . ASP F 2 162 ? 223.960 292.685 301.450 1.00 83.38  ? 160 ASP F CB  1 
ATOM   15962 C  CG  . ASP F 2 162 ? 222.950 293.057 302.518 1.00 88.27  ? 160 ASP F CG  1 
ATOM   15963 O  OD1 . ASP F 2 162 ? 222.816 294.262 302.818 1.00 88.71  ? 160 ASP F OD1 1 
ATOM   15964 O  OD2 . ASP F 2 162 ? 222.290 292.145 303.055 1.00 89.32  ? 160 ASP F OD2 1 
ATOM   15965 N  N   . ILE F 2 163 ? 224.269 292.617 298.228 1.00 71.30  ? 161 ILE F N   1 
ATOM   15966 C  CA  . ILE F 2 163 ? 224.989 292.068 297.074 1.00 68.30  ? 161 ILE F CA  1 
ATOM   15967 C  C   . ILE F 2 163 ? 225.590 293.213 296.266 1.00 66.96  ? 161 ILE F C   1 
ATOM   15968 O  O   . ILE F 2 163 ? 224.870 294.162 295.912 1.00 68.15  ? 161 ILE F O   1 
ATOM   15969 C  CB  . ILE F 2 163 ? 224.052 291.221 296.212 1.00 67.57  ? 161 ILE F CB  1 
ATOM   15970 C  CG1 . ILE F 2 163 ? 223.372 290.148 297.061 1.00 69.79  ? 161 ILE F CG1 1 
ATOM   15971 C  CG2 . ILE F 2 163 ? 224.815 290.588 295.059 1.00 60.47  ? 161 ILE F CG2 1 
ATOM   15972 C  CD1 . ILE F 2 163 ? 222.292 289.386 296.327 1.00 70.14  ? 161 ILE F CD1 1 
ATOM   15973 N  N   . PRO F 2 164 ? 226.882 293.173 295.948 1.00 65.00  ? 162 PRO F N   1 
ATOM   15974 C  CA  . PRO F 2 164 ? 227.520 294.268 295.196 1.00 59.01  ? 162 PRO F CA  1 
ATOM   15975 C  C   . PRO F 2 164 ? 227.310 294.143 293.689 1.00 55.65  ? 162 PRO F C   1 
ATOM   15976 O  O   . PRO F 2 164 ? 228.256 294.106 292.901 1.00 59.28  ? 162 PRO F O   1 
ATOM   15977 C  CB  . PRO F 2 164 ? 228.997 294.131 295.599 1.00 58.75  ? 162 PRO F CB  1 
ATOM   15978 C  CG  . PRO F 2 164 ? 229.106 292.866 296.445 1.00 57.20  ? 162 PRO F CG  1 
ATOM   15979 C  CD  . PRO F 2 164 ? 227.838 292.112 296.291 1.00 56.67  ? 162 PRO F CD  1 
ATOM   15980 N  N   . SER F 2 165 ? 226.043 294.074 293.278 1.00 56.71  ? 163 SER F N   1 
ATOM   15981 C  CA  . SER F 2 165 ? 225.742 293.987 291.853 1.00 52.10  ? 163 SER F CA  1 
ATOM   15982 C  C   . SER F 2 165 ? 226.199 295.238 291.115 1.00 52.82  ? 163 SER F C   1 
ATOM   15983 O  O   . SER F 2 165 ? 226.767 295.150 290.021 1.00 55.50  ? 163 SER F O   1 
ATOM   15984 C  CB  . SER F 2 165 ? 224.246 293.757 291.642 1.00 51.74  ? 163 SER F CB  1 
ATOM   15985 O  OG  . SER F 2 165 ? 223.829 292.543 292.240 1.00 61.69  ? 163 SER F OG  1 
ATOM   15986 N  N   . ALA F 2 166 ? 225.959 296.414 291.697 1.00 54.24  ? 164 ALA F N   1 
ATOM   15987 C  CA  . ALA F 2 166 ? 226.350 297.667 291.068 1.00 55.72  ? 164 ALA F CA  1 
ATOM   15988 C  C   . ALA F 2 166 ? 227.781 298.074 291.382 1.00 55.63  ? 164 ALA F C   1 
ATOM   15989 O  O   . ALA F 2 166 ? 228.342 298.912 290.667 1.00 52.96  ? 164 ALA F O   1 
ATOM   15990 C  CB  . ALA F 2 166 ? 225.402 298.792 291.491 1.00 53.93  ? 164 ALA F CB  1 
ATOM   15991 N  N   . GLU F 2 167 ? 228.383 297.505 292.429 1.00 54.31  ? 165 GLU F N   1 
ATOM   15992 C  CA  . GLU F 2 167 ? 229.769 297.825 292.753 1.00 53.75  ? 165 GLU F CA  1 
ATOM   15993 C  C   . GLU F 2 167 ? 230.740 297.131 291.808 1.00 52.75  ? 165 GLU F C   1 
ATOM   15994 O  O   . GLU F 2 167 ? 231.767 297.709 291.437 1.00 51.47  ? 165 GLU F O   1 
ATOM   15995 C  CB  . GLU F 2 167 ? 230.072 297.447 294.202 1.00 58.84  ? 165 GLU F CB  1 
ATOM   15996 C  CG  . GLU F 2 167 ? 229.682 298.511 295.212 1.00 64.76  ? 165 GLU F CG  1 
ATOM   15997 C  CD  . GLU F 2 167 ? 228.184 298.717 295.295 1.00 70.02  ? 165 GLU F CD  1 
ATOM   15998 O  OE1 . GLU F 2 167 ? 227.449 297.714 295.407 1.00 70.27  ? 165 GLU F OE1 1 
ATOM   15999 O  OE2 . GLU F 2 167 ? 227.741 299.884 295.248 1.00 67.81  ? 165 GLU F OE2 1 
ATOM   16000 N  N   . VAL F 2 168 ? 230.435 295.900 291.406 1.00 48.47  ? 166 VAL F N   1 
ATOM   16001 C  CA  . VAL F 2 168 ? 231.283 295.186 290.457 1.00 45.37  ? 166 VAL F CA  1 
ATOM   16002 C  C   . VAL F 2 168 ? 231.211 295.928 289.128 1.00 47.07  ? 166 VAL F C   1 
ATOM   16003 O  O   . VAL F 2 168 ? 230.188 295.890 288.439 1.00 47.38  ? 166 VAL F O   1 
ATOM   16004 C  CB  . VAL F 2 168 ? 230.855 293.723 290.306 1.00 46.53  ? 166 VAL F CB  1 
ATOM   16005 C  CG1 . VAL F 2 168 ? 231.376 293.156 288.997 1.00 38.91  ? 166 VAL F CG1 1 
ATOM   16006 C  CG2 . VAL F 2 168 ? 231.352 292.904 291.484 1.00 47.19  ? 166 VAL F CG2 1 
ATOM   16007 N  N   . LYS F 2 169 ? 232.302 296.597 288.758 1.00 45.47  ? 167 LYS F N   1 
ATOM   16008 C  CA  . LYS F 2 169 ? 232.284 297.481 287.598 1.00 37.28  ? 167 LYS F CA  1 
ATOM   16009 C  C   . LYS F 2 169 ? 233.352 297.141 286.568 1.00 37.65  ? 167 LYS F C   1 
ATOM   16010 O  O   . LYS F 2 169 ? 233.592 297.940 285.657 1.00 41.72  ? 167 LYS F O   1 
ATOM   16011 C  CB  . LYS F 2 169 ? 232.430 298.942 288.035 1.00 43.48  ? 167 LYS F CB  1 
ATOM   16012 C  CG  . LYS F 2 169 ? 231.103 299.647 288.253 1.00 46.66  ? 167 LYS F CG  1 
ATOM   16013 C  CD  . LYS F 2 169 ? 231.209 300.698 289.340 1.00 50.48  ? 167 LYS F CD  1 
ATOM   16014 C  CE  . LYS F 2 169 ? 230.029 301.649 289.302 1.00 52.70  ? 167 LYS F CE  1 
ATOM   16015 N  NZ  . LYS F 2 169 ? 230.466 303.069 289.372 1.00 53.33  ? 167 LYS F NZ  1 
ATOM   16016 N  N   . ALA F 2 170 ? 233.991 295.982 286.681 1.00 40.72  ? 168 ALA F N   1 
ATOM   16017 C  CA  . ALA F 2 170 ? 234.954 295.545 285.683 1.00 34.23  ? 168 ALA F CA  1 
ATOM   16018 C  C   . ALA F 2 170 ? 235.059 294.032 285.751 1.00 35.39  ? 168 ALA F C   1 
ATOM   16019 O  O   . ALA F 2 170 ? 234.688 293.410 286.749 1.00 37.53  ? 168 ALA F O   1 
ATOM   16020 C  CB  . ALA F 2 170 ? 236.324 296.198 285.893 1.00 33.56  ? 168 ALA F CB  1 
ATOM   16021 N  N   . TYR F 2 171 ? 235.562 293.448 284.669 1.00 35.16  ? 169 TYR F N   1 
ATOM   16022 C  CA  . TYR F 2 171 ? 235.766 292.011 284.596 1.00 29.32  ? 169 TYR F CA  1 
ATOM   16023 C  C   . TYR F 2 171 ? 237.140 291.706 284.020 1.00 30.34  ? 169 TYR F C   1 
ATOM   16024 O  O   . TYR F 2 171 ? 237.658 292.443 283.179 1.00 32.52  ? 169 TYR F O   1 
ATOM   16025 C  CB  . TYR F 2 171 ? 234.693 291.325 283.739 1.00 30.77  ? 169 TYR F CB  1 
ATOM   16026 C  CG  . TYR F 2 171 ? 233.404 291.044 284.471 1.00 29.98  ? 169 TYR F CG  1 
ATOM   16027 C  CD1 . TYR F 2 171 ? 232.385 291.984 284.502 1.00 31.93  ? 169 TYR F CD1 1 
ATOM   16028 C  CD2 . TYR F 2 171 ? 233.204 289.839 285.129 1.00 30.23  ? 169 TYR F CD2 1 
ATOM   16029 C  CE1 . TYR F 2 171 ? 231.206 291.735 285.167 1.00 30.99  ? 169 TYR F CE1 1 
ATOM   16030 C  CE2 . TYR F 2 171 ? 232.025 289.581 285.798 1.00 32.78  ? 169 TYR F CE2 1 
ATOM   16031 C  CZ  . TYR F 2 171 ? 231.030 290.534 285.813 1.00 33.97  ? 169 TYR F CZ  1 
ATOM   16032 O  OH  . TYR F 2 171 ? 229.852 290.287 286.476 1.00 36.42  ? 169 TYR F OH  1 
ATOM   16033 N  N   . TYR F 2 172 ? 237.724 290.607 284.484 1.00 32.67  ? 170 TYR F N   1 
ATOM   16034 C  CA  . TYR F 2 172 ? 238.921 290.038 283.883 1.00 28.71  ? 170 TYR F CA  1 
ATOM   16035 C  C   . TYR F 2 172 ? 238.498 288.906 282.960 1.00 30.00  ? 170 TYR F C   1 
ATOM   16036 O  O   . TYR F 2 172 ? 237.867 287.942 283.405 1.00 35.25  ? 170 TYR F O   1 
ATOM   16037 C  CB  . TYR F 2 172 ? 239.889 289.524 284.946 1.00 32.29  ? 170 TYR F CB  1 
ATOM   16038 C  CG  . TYR F 2 172 ? 240.699 290.602 285.617 1.00 33.18  ? 170 TYR F CG  1 
ATOM   16039 C  CD1 . TYR F 2 172 ? 241.164 291.694 284.899 1.00 32.75  ? 170 TYR F CD1 1 
ATOM   16040 C  CD2 . TYR F 2 172 ? 241.001 290.527 286.967 1.00 33.77  ? 170 TYR F CD2 1 
ATOM   16041 C  CE1 . TYR F 2 172 ? 241.906 292.679 285.508 1.00 34.58  ? 170 TYR F CE1 1 
ATOM   16042 C  CE2 . TYR F 2 172 ? 241.743 291.508 287.585 1.00 38.02  ? 170 TYR F CE2 1 
ATOM   16043 C  CZ  . TYR F 2 172 ? 242.193 292.583 286.851 1.00 41.09  ? 170 TYR F CZ  1 
ATOM   16044 O  OH  . TYR F 2 172 ? 242.933 293.565 287.466 1.00 46.86  ? 170 TYR F OH  1 
ATOM   16045 N  N   . VAL F 2 173 ? 238.844 289.020 281.684 1.00 27.86  ? 171 VAL F N   1 
ATOM   16046 C  CA  . VAL F 2 173 ? 238.510 288.012 280.688 1.00 28.32  ? 171 VAL F CA  1 
ATOM   16047 C  C   . VAL F 2 173 ? 239.804 287.349 280.247 1.00 29.07  ? 171 VAL F C   1 
ATOM   16048 O  O   . VAL F 2 173 ? 240.736 288.025 279.793 1.00 31.74  ? 171 VAL F O   1 
ATOM   16049 C  CB  . VAL F 2 173 ? 237.759 288.616 279.494 1.00 31.85  ? 171 VAL F CB  1 
ATOM   16050 C  CG1 . VAL F 2 173 ? 237.388 287.529 278.502 1.00 27.20  ? 171 VAL F CG1 1 
ATOM   16051 C  CG2 . VAL F 2 173 ? 236.519 289.352 279.970 1.00 29.70  ? 171 VAL F CG2 1 
ATOM   16052 N  N   . LYS F 2 174 ? 239.863 286.031 280.392 1.00 31.02  ? 172 LYS F N   1 
ATOM   16053 C  CA  . LYS F 2 174 ? 241.007 285.235 279.966 1.00 27.57  ? 172 LYS F CA  1 
ATOM   16054 C  C   . LYS F 2 174 ? 240.658 284.624 278.616 1.00 28.51  ? 172 LYS F C   1 
ATOM   16055 O  O   . LYS F 2 174 ? 239.934 283.629 278.541 1.00 29.67  ? 172 LYS F O   1 
ATOM   16056 C  CB  . LYS F 2 174 ? 241.338 284.168 281.004 1.00 29.32  ? 172 LYS F CB  1 
ATOM   16057 C  CG  . LYS F 2 174 ? 242.676 283.489 280.794 1.00 30.96  ? 172 LYS F CG  1 
ATOM   16058 C  CD  . LYS F 2 174 ? 242.835 282.306 281.726 1.00 32.27  ? 172 LYS F CD  1 
ATOM   16059 C  CE  . LYS F 2 174 ? 244.265 281.805 281.738 1.00 35.73  ? 172 LYS F CE  1 
ATOM   16060 N  NZ  . LYS F 2 174 ? 244.335 280.361 282.085 1.00 37.19  ? 172 LYS F NZ  1 
ATOM   16061 N  N   . GLU F 2 175 ? 241.169 285.226 277.549 1.00 27.91  ? 173 GLU F N   1 
ATOM   16062 C  CA  . GLU F 2 175 ? 240.937 284.755 276.196 1.00 29.30  ? 173 GLU F CA  1 
ATOM   16063 C  C   . GLU F 2 175 ? 242.118 283.919 275.730 1.00 30.68  ? 173 GLU F C   1 
ATOM   16064 O  O   . GLU F 2 175 ? 243.256 284.122 276.159 1.00 34.89  ? 173 GLU F O   1 
ATOM   16065 C  CB  . GLU F 2 175 ? 240.740 285.920 275.226 1.00 32.94  ? 173 GLU F CB  1 
ATOM   16066 C  CG  . GLU F 2 175 ? 239.960 287.094 275.768 1.00 32.86  ? 173 GLU F CG  1 
ATOM   16067 C  CD  . GLU F 2 175 ? 239.972 288.262 274.806 1.00 39.71  ? 173 GLU F CD  1 
ATOM   16068 O  OE1 . GLU F 2 175 ? 240.851 288.286 273.919 1.00 35.23  ? 173 GLU F OE1 1 
ATOM   16069 O  OE2 . GLU F 2 175 ? 239.109 289.153 274.930 1.00 45.21  ? 173 GLU F OE2 1 
ATOM   16070 N  N   . GLU F 2 176 ? 241.836 282.978 274.839 1.00 30.74  ? 174 GLU F N   1 
ATOM   16071 C  CA  . GLU F 2 176 ? 242.866 282.195 274.169 1.00 31.19  ? 174 GLU F CA  1 
ATOM   16072 C  C   . GLU F 2 176 ? 242.612 282.300 272.674 1.00 29.49  ? 174 GLU F C   1 
ATOM   16073 O  O   . GLU F 2 176 ? 241.606 281.787 272.176 1.00 29.69  ? 174 GLU F O   1 
ATOM   16074 C  CB  . GLU F 2 176 ? 242.845 280.741 274.634 1.00 32.85  ? 174 GLU F CB  1 
ATOM   16075 C  CG  . GLU F 2 176 ? 243.675 279.808 273.779 1.00 35.36  ? 174 GLU F CG  1 
ATOM   16076 C  CD  . GLU F 2 176 ? 243.406 278.353 274.090 1.00 51.92  ? 174 GLU F CD  1 
ATOM   16077 O  OE1 . GLU F 2 176 ? 242.409 278.071 274.785 1.00 53.41  ? 174 GLU F OE1 1 
ATOM   16078 O  OE2 . GLU F 2 176 ? 244.186 277.490 273.636 1.00 54.97  ? 174 GLU F OE2 1 
ATOM   16079 N  N   . TRP F 2 177 ? 243.492 283.008 271.972 1.00 28.19  ? 175 TRP F N   1 
ATOM   16080 C  CA  . TRP F 2 177 ? 243.472 283.011 270.518 1.00 27.29  ? 175 TRP F CA  1 
ATOM   16081 C  C   . TRP F 2 177 ? 244.196 281.769 270.024 1.00 28.97  ? 175 TRP F C   1 
ATOM   16082 O  O   . TRP F 2 177 ? 245.280 281.440 270.517 1.00 34.00  ? 175 TRP F O   1 
ATOM   16083 C  CB  . TRP F 2 177 ? 244.139 284.269 269.961 1.00 27.84  ? 175 TRP F CB  1 
ATOM   16084 C  CG  . TRP F 2 177 ? 243.549 285.574 270.421 1.00 25.94  ? 175 TRP F CG  1 
ATOM   16085 C  CD1 . TRP F 2 177 ? 243.225 285.929 271.697 1.00 28.51  ? 175 TRP F CD1 1 
ATOM   16086 C  CD2 . TRP F 2 177 ? 243.239 286.706 269.601 1.00 27.43  ? 175 TRP F CD2 1 
ATOM   16087 N  NE1 . TRP F 2 177 ? 242.723 287.205 271.721 1.00 31.06  ? 175 TRP F NE1 1 
ATOM   16088 C  CE2 . TRP F 2 177 ? 242.722 287.705 270.446 1.00 28.82  ? 175 TRP F CE2 1 
ATOM   16089 C  CE3 . TRP F 2 177 ? 243.346 286.970 268.232 1.00 29.41  ? 175 TRP F CE3 1 
ATOM   16090 C  CZ2 . TRP F 2 177 ? 242.310 288.946 269.969 1.00 31.15  ? 175 TRP F CZ2 1 
ATOM   16091 C  CZ3 . TRP F 2 177 ? 242.938 288.201 267.761 1.00 31.27  ? 175 TRP F CZ3 1 
ATOM   16092 C  CH2 . TRP F 2 177 ? 242.427 289.174 268.627 1.00 31.98  ? 175 TRP F CH2 1 
ATOM   16093 N  N   . TYR F 2 178 ? 243.599 281.078 269.060 1.00 27.03  ? 176 TYR F N   1 
ATOM   16094 C  CA  . TYR F 2 178 ? 244.175 279.845 268.553 1.00 26.38  ? 176 TYR F CA  1 
ATOM   16095 C  C   . TYR F 2 178 ? 243.972 279.754 267.049 1.00 28.25  ? 176 TYR F C   1 
ATOM   16096 O  O   . TYR F 2 178 ? 243.079 280.383 266.474 1.00 29.50  ? 176 TYR F O   1 
ATOM   16097 C  CB  . TYR F 2 178 ? 243.582 278.609 269.245 1.00 30.73  ? 176 TYR F CB  1 
ATOM   16098 C  CG  . TYR F 2 178 ? 242.094 278.437 269.058 1.00 33.70  ? 176 TYR F CG  1 
ATOM   16099 C  CD1 . TYR F 2 178 ? 241.192 279.126 269.856 1.00 34.22  ? 176 TYR F CD1 1 
ATOM   16100 C  CD2 . TYR F 2 178 ? 241.591 277.577 268.093 1.00 32.95  ? 176 TYR F CD2 1 
ATOM   16101 C  CE1 . TYR F 2 178 ? 239.832 278.968 269.692 1.00 33.68  ? 176 TYR F CE1 1 
ATOM   16102 C  CE2 . TYR F 2 178 ? 240.233 277.414 267.922 1.00 38.18  ? 176 TYR F CE2 1 
ATOM   16103 C  CZ  . TYR F 2 178 ? 239.358 278.112 268.724 1.00 37.85  ? 176 TYR F CZ  1 
ATOM   16104 O  OH  . TYR F 2 178 ? 238.004 277.952 268.558 1.00 42.24  ? 176 TYR F OH  1 
ATOM   16105 N  N   . PHE F 2 179 ? 244.832 278.960 266.423 1.00 27.98  ? 177 PHE F N   1 
ATOM   16106 C  CA  . PHE F 2 179 ? 244.801 278.701 264.991 1.00 29.11  ? 177 PHE F CA  1 
ATOM   16107 C  C   . PHE F 2 179 ? 244.332 277.267 264.780 1.00 33.26  ? 177 PHE F C   1 
ATOM   16108 O  O   . PHE F 2 179 ? 244.986 276.324 265.238 1.00 37.01  ? 177 PHE F O   1 
ATOM   16109 C  CB  . PHE F 2 179 ? 246.183 278.931 264.378 1.00 26.85  ? 177 PHE F CB  1 
ATOM   16110 C  CG  . PHE F 2 179 ? 246.269 278.602 262.919 1.00 29.64  ? 177 PHE F CG  1 
ATOM   16111 C  CD1 . PHE F 2 179 ? 245.903 279.532 261.964 1.00 27.92  ? 177 PHE F CD1 1 
ATOM   16112 C  CD2 . PHE F 2 179 ? 246.735 277.368 262.501 1.00 30.40  ? 177 PHE F CD2 1 
ATOM   16113 C  CE1 . PHE F 2 179 ? 245.989 279.234 260.622 1.00 28.82  ? 177 PHE F CE1 1 
ATOM   16114 C  CE2 . PHE F 2 179 ? 246.821 277.065 261.163 1.00 28.15  ? 177 PHE F CE2 1 
ATOM   16115 C  CZ  . PHE F 2 179 ? 246.449 277.999 260.221 1.00 26.81  ? 177 PHE F CZ  1 
ATOM   16116 N  N   . THR F 2 180 ? 243.207 277.108 264.098 1.00 33.01  ? 178 THR F N   1 
ATOM   16117 C  CA  . THR F 2 180 ? 242.623 275.783 263.925 1.00 33.50  ? 178 THR F CA  1 
ATOM   16118 C  C   . THR F 2 180 ? 243.445 274.976 262.928 1.00 36.10  ? 178 THR F C   1 
ATOM   16119 O  O   . THR F 2 180 ? 243.690 275.445 261.810 1.00 38.37  ? 178 THR F O   1 
ATOM   16120 C  CB  . THR F 2 180 ? 241.177 275.892 263.450 1.00 38.15  ? 178 THR F CB  1 
ATOM   16121 O  OG1 . THR F 2 180 ? 240.334 276.233 264.556 1.00 38.84  ? 178 THR F OG1 1 
ATOM   16122 C  CG2 . THR F 2 180 ? 240.711 274.573 262.857 1.00 40.50  ? 178 THR F CG2 1 
ATOM   16123 N  N   . PRO F 2 181 ? 243.888 273.771 263.285 1.00 38.69  ? 179 PRO F N   1 
ATOM   16124 C  CA  . PRO F 2 181 ? 244.702 272.979 262.353 1.00 39.93  ? 179 PRO F CA  1 
ATOM   16125 C  C   . PRO F 2 181 ? 243.934 272.552 261.113 1.00 42.21  ? 179 PRO F C   1 
ATOM   16126 O  O   . PRO F 2 181 ? 244.396 272.759 259.987 1.00 45.19  ? 179 PRO F O   1 
ATOM   16127 C  CB  . PRO F 2 181 ? 245.120 271.767 263.196 1.00 36.83  ? 179 PRO F CB  1 
ATOM   16128 C  CG  . PRO F 2 181 ? 244.093 271.678 264.275 1.00 38.13  ? 179 PRO F CG  1 
ATOM   16129 C  CD  . PRO F 2 181 ? 243.683 273.085 264.572 1.00 39.87  ? 179 PRO F CD  1 
ATOM   16130 N  N   . THR F 2 182 ? 242.755 271.958 261.308 1.00 38.55  ? 180 THR F N   1 
ATOM   16131 C  CA  . THR F 2 182 ? 241.993 271.437 260.177 1.00 38.26  ? 180 THR F CA  1 
ATOM   16132 C  C   . THR F 2 182 ? 241.480 272.556 259.277 1.00 37.29  ? 180 THR F C   1 
ATOM   16133 O  O   . THR F 2 182 ? 241.558 272.453 258.048 1.00 35.52  ? 180 THR F O   1 
ATOM   16134 C  CB  . THR F 2 182 ? 240.825 270.585 260.675 1.00 40.95  ? 180 THR F CB  1 
ATOM   16135 O  OG1 . THR F 2 182 ? 239.981 271.377 261.519 1.00 50.79  ? 180 THR F OG1 1 
ATOM   16136 C  CG2 . THR F 2 182 ? 241.332 269.386 261.458 1.00 34.70  ? 180 THR F CG2 1 
ATOM   16137 N  N   . ASN F 2 183 ? 240.945 273.625 259.865 1.00 41.89  ? 181 ASN F N   1 
ATOM   16138 C  CA  . ASN F 2 183 ? 240.286 274.668 259.087 1.00 38.23  ? 181 ASN F CA  1 
ATOM   16139 C  C   . ASN F 2 183 ? 241.228 275.785 258.659 1.00 38.45  ? 181 ASN F C   1 
ATOM   16140 O  O   . ASN F 2 183 ? 240.966 276.450 257.650 1.00 35.95  ? 181 ASN F O   1 
ATOM   16141 C  CB  . ASN F 2 183 ? 239.123 275.263 259.886 1.00 36.73  ? 181 ASN F CB  1 
ATOM   16142 C  CG  . ASN F 2 183 ? 237.864 275.405 259.060 1.00 40.71  ? 181 ASN F CG  1 
ATOM   16143 O  OD1 . ASN F 2 183 ? 237.700 274.734 258.042 1.00 48.05  ? 181 ASN F OD1 1 
ATOM   16144 N  ND2 . ASN F 2 183 ? 236.968 276.283 259.491 1.00 42.15  ? 181 ASN F ND2 1 
ATOM   16145 N  N   . SER F 2 184 ? 242.314 276.012 259.402 1.00 38.33  ? 182 SER F N   1 
ATOM   16146 C  CA  . SER F 2 184 ? 243.288 277.057 259.080 1.00 32.51  ? 182 SER F CA  1 
ATOM   16147 C  C   . SER F 2 184 ? 242.683 278.454 259.245 1.00 36.34  ? 182 SER F C   1 
ATOM   16148 O  O   . SER F 2 184 ? 242.827 279.319 258.381 1.00 38.09  ? 182 SER F O   1 
ATOM   16149 C  CB  . SER F 2 184 ? 243.851 276.871 257.668 1.00 30.69  ? 182 SER F CB  1 
ATOM   16150 O  OG  . SER F 2 184 ? 244.902 275.921 257.653 1.00 40.12  ? 182 SER F OG  1 
ATOM   16151 N  N   . ASP F 2 185 ? 242.002 278.669 260.368 1.00 37.57  ? 183 ASP F N   1 
ATOM   16152 C  CA  . ASP F 2 185 ? 241.445 279.974 260.690 1.00 38.71  ? 183 ASP F CA  1 
ATOM   16153 C  C   . ASP F 2 185 ? 241.699 280.285 262.158 1.00 35.30  ? 183 ASP F C   1 
ATOM   16154 O  O   . ASP F 2 185 ? 241.901 279.388 262.980 1.00 35.44  ? 183 ASP F O   1 
ATOM   16155 C  CB  . ASP F 2 185 ? 239.944 280.049 260.379 1.00 36.97  ? 183 ASP F CB  1 
ATOM   16156 C  CG  . ASP F 2 185 ? 239.155 278.942 261.038 1.00 43.18  ? 183 ASP F CG  1 
ATOM   16157 O  OD1 . ASP F 2 185 ? 239.522 278.527 262.156 1.00 47.89  ? 183 ASP F OD1 1 
ATOM   16158 O  OD2 . ASP F 2 185 ? 238.163 278.486 260.436 1.00 46.77  ? 183 ASP F OD2 1 
ATOM   16159 N  N   . VAL F 2 186 ? 241.684 281.570 262.476 1.00 35.01  ? 184 VAL F N   1 
ATOM   16160 C  CA  . VAL F 2 186 ? 241.956 282.048 263.826 1.00 34.97  ? 184 VAL F CA  1 
ATOM   16161 C  C   . VAL F 2 186 ? 240.643 282.246 264.566 1.00 32.22  ? 184 VAL F C   1 
ATOM   16162 O  O   . VAL F 2 186 ? 239.668 282.764 264.008 1.00 34.41  ? 184 VAL F O   1 
ATOM   16163 C  CB  . VAL F 2 186 ? 242.778 283.349 263.788 1.00 30.62  ? 184 VAL F CB  1 
ATOM   16164 C  CG1 . VAL F 2 186 ? 242.991 283.882 265.193 1.00 32.08  ? 184 VAL F CG1 1 
ATOM   16165 C  CG2 . VAL F 2 186 ? 244.107 283.105 263.101 1.00 28.02  ? 184 VAL F CG2 1 
ATOM   16166 N  N   . ASP F 2 187 ? 240.613 281.827 265.829 1.00 31.85  ? 185 ASP F N   1 
ATOM   16167 C  CA  . ASP F 2 187 ? 239.431 281.980 266.663 1.00 29.74  ? 185 ASP F CA  1 
ATOM   16168 C  C   . ASP F 2 187 ? 239.851 282.349 268.077 1.00 29.41  ? 185 ASP F C   1 
ATOM   16169 O  O   . ASP F 2 187 ? 241.022 282.245 268.450 1.00 31.57  ? 185 ASP F O   1 
ATOM   16170 C  CB  . ASP F 2 187 ? 238.577 280.709 266.670 1.00 35.54  ? 185 ASP F CB  1 
ATOM   16171 C  CG  . ASP F 2 187 ? 237.097 281.004 266.781 1.00 38.28  ? 185 ASP F CG  1 
ATOM   16172 O  OD1 . ASP F 2 187 ? 236.742 282.164 267.078 1.00 35.77  ? 185 ASP F OD1 1 
ATOM   16173 O  OD2 . ASP F 2 187 ? 236.288 280.078 266.570 1.00 42.00  ? 185 ASP F OD2 1 
ATOM   16174 N  N   . ILE F 2 188 ? 238.876 282.795 268.865 1.00 33.12  ? 186 ILE F N   1 
ATOM   16175 C  CA  . ILE F 2 188 ? 239.082 283.175 270.256 1.00 30.84  ? 186 ILE F CA  1 
ATOM   16176 C  C   . ILE F 2 188 ? 238.171 282.324 271.129 1.00 29.69  ? 186 ILE F C   1 
ATOM   16177 O  O   . ILE F 2 188 ? 237.016 282.069 270.773 1.00 31.28  ? 186 ILE F O   1 
ATOM   16178 C  CB  . ILE F 2 188 ? 238.811 284.677 270.487 1.00 32.00  ? 186 ILE F CB  1 
ATOM   16179 C  CG1 . ILE F 2 188 ? 239.688 285.528 269.569 1.00 32.43  ? 186 ILE F CG1 1 
ATOM   16180 C  CG2 . ILE F 2 188 ? 239.053 285.048 271.939 1.00 26.53  ? 186 ILE F CG2 1 
ATOM   16181 C  CD1 . ILE F 2 188 ? 239.312 286.991 269.558 1.00 33.59  ? 186 ILE F CD1 1 
ATOM   16182 N  N   . LYS F 2 189 ? 238.696 281.881 272.267 1.00 29.30  ? 187 LYS F N   1 
ATOM   16183 C  CA  . LYS F 2 189 ? 237.946 281.065 273.213 1.00 25.53  ? 187 LYS F CA  1 
ATOM   16184 C  C   . LYS F 2 189 ? 238.053 281.677 274.601 1.00 31.08  ? 187 LYS F C   1 
ATOM   16185 O  O   . LYS F 2 189 ? 239.156 281.976 275.064 1.00 33.41  ? 187 LYS F O   1 
ATOM   16186 C  CB  . LYS F 2 189 ? 238.471 279.627 273.219 1.00 29.13  ? 187 LYS F CB  1 
ATOM   16187 C  CG  . LYS F 2 189 ? 237.737 278.689 274.151 1.00 33.30  ? 187 LYS F CG  1 
ATOM   16188 C  CD  . LYS F 2 189 ? 238.375 277.312 274.136 1.00 38.63  ? 187 LYS F CD  1 
ATOM   16189 C  CE  . LYS F 2 189 ? 238.121 276.563 275.430 1.00 40.34  ? 187 LYS F CE  1 
ATOM   16190 N  NZ  . LYS F 2 189 ? 236.670 276.399 275.708 1.00 48.02  ? 187 LYS F NZ  1 
ATOM   16191 N  N   . ILE F 2 190 ? 236.915 281.862 275.261 1.00 32.23  ? 188 ILE F N   1 
ATOM   16192 C  CA  . ILE F 2 190 ? 236.907 282.393 276.620 1.00 26.02  ? 188 ILE F CA  1 
ATOM   16193 C  C   . ILE F 2 190 ? 237.190 281.261 277.597 1.00 31.78  ? 188 ILE F C   1 
ATOM   16194 O  O   . ILE F 2 190 ? 236.592 280.183 277.508 1.00 34.75  ? 188 ILE F O   1 
ATOM   16195 C  CB  . ILE F 2 190 ? 235.567 283.076 276.935 1.00 29.95  ? 188 ILE F CB  1 
ATOM   16196 C  CG1 . ILE F 2 190 ? 235.139 283.977 275.776 1.00 32.22  ? 188 ILE F CG1 1 
ATOM   16197 C  CG2 . ILE F 2 190 ? 235.669 283.875 278.225 1.00 29.81  ? 188 ILE F CG2 1 
ATOM   16198 C  CD1 . ILE F 2 190 ? 235.767 285.346 275.811 1.00 30.09  ? 188 ILE F CD1 1 
ATOM   16199 N  N   . GLN F 2 191 ? 238.106 281.504 278.532 1.00 32.98  ? 189 GLN F N   1 
ATOM   16200 C  CA  . GLN F 2 191 ? 238.478 280.516 279.536 1.00 32.40  ? 189 GLN F CA  1 
ATOM   16201 C  C   . GLN F 2 191 ? 237.864 280.808 280.899 1.00 34.31  ? 189 GLN F C   1 
ATOM   16202 O  O   . GLN F 2 191 ? 237.292 279.911 281.525 1.00 38.89  ? 189 GLN F O   1 
ATOM   16203 C  CB  . GLN F 2 191 ? 240.005 280.438 279.657 1.00 32.30  ? 189 GLN F CB  1 
ATOM   16204 C  CG  . GLN F 2 191 ? 240.723 280.277 278.330 1.00 32.29  ? 189 GLN F CG  1 
ATOM   16205 C  CD  . GLN F 2 191 ? 240.870 278.827 277.920 1.00 44.66  ? 189 GLN F CD  1 
ATOM   16206 O  OE1 . GLN F 2 191 ? 239.903 278.066 277.931 1.00 49.29  ? 189 GLN F OE1 1 
ATOM   16207 N  NE2 . GLN F 2 191 ? 242.084 278.436 277.556 1.00 45.16  ? 189 GLN F NE2 1 
ATOM   16208 N  N   . ALA F 2 192 ? 237.974 282.045 281.376 1.00 32.01  ? 190 ALA F N   1 
ATOM   16209 C  CA  . ALA F 2 192 ? 237.437 282.403 282.681 1.00 31.08  ? 190 ALA F CA  1 
ATOM   16210 C  C   . ALA F 2 192 ? 237.217 283.907 282.733 1.00 33.36  ? 190 ALA F C   1 
ATOM   16211 O  O   . ALA F 2 192 ? 237.785 284.664 281.943 1.00 37.02  ? 190 ALA F O   1 
ATOM   16212 C  CB  . ALA F 2 192 ? 238.368 281.954 283.812 1.00 32.63  ? 190 ALA F CB  1 
ATOM   16213 N  N   . ILE F 2 193 ? 236.383 284.327 283.681 1.00 31.07  ? 191 ILE F N   1 
ATOM   16214 C  CA  . ILE F 2 193 ? 236.081 285.734 283.909 1.00 31.58  ? 191 ILE F CA  1 
ATOM   16215 C  C   . ILE F 2 193 ? 236.131 286.002 285.406 1.00 34.94  ? 191 ILE F C   1 
ATOM   16216 O  O   . ILE F 2 193 ? 235.720 285.160 286.211 1.00 36.71  ? 191 ILE F O   1 
ATOM   16217 C  CB  . ILE F 2 193 ? 234.709 286.130 283.326 1.00 33.81  ? 191 ILE F CB  1 
ATOM   16218 C  CG1 . ILE F 2 193 ? 233.597 285.277 283.938 1.00 34.30  ? 191 ILE F CG1 1 
ATOM   16219 C  CG2 . ILE F 2 193 ? 234.713 285.996 281.812 1.00 28.77  ? 191 ILE F CG2 1 
ATOM   16220 C  CD1 . ILE F 2 193 ? 232.209 285.692 283.506 1.00 26.68  ? 191 ILE F CD1 1 
ATOM   16221 N  N   . CYS F 2 194 ? 236.643 287.173 285.778 1.00 33.64  ? 192 CYS F N   1 
ATOM   16222 C  CA  . CYS F 2 194 ? 236.783 287.560 287.176 1.00 33.80  ? 192 CYS F CA  1 
ATOM   16223 C  C   . CYS F 2 194 ? 236.084 288.890 287.418 1.00 34.62  ? 192 CYS F C   1 
ATOM   16224 O  O   . CYS F 2 194 ? 236.495 289.912 286.842 1.00 35.85  ? 192 CYS F O   1 
ATOM   16225 C  CB  . CYS F 2 194 ? 238.260 287.655 287.566 1.00 34.30  ? 192 CYS F CB  1 
ATOM   16226 S  SG  . CYS F 2 194 ? 238.555 288.223 289.254 1.00 50.26  ? 192 CYS F SG  1 
ATOM   16227 N  N   . PRO F 2 195 ? 235.043 288.940 288.247 1.00 38.35  ? 193 PRO F N   1 
ATOM   16228 C  CA  . PRO F 2 195 ? 234.408 290.227 288.550 1.00 34.90  ? 193 PRO F CA  1 
ATOM   16229 C  C   . PRO F 2 195 ? 235.289 291.071 289.457 1.00 41.16  ? 193 PRO F C   1 
ATOM   16230 O  O   . PRO F 2 195 ? 235.968 290.554 290.348 1.00 42.31  ? 193 PRO F O   1 
ATOM   16231 C  CB  . PRO F 2 195 ? 233.100 289.831 289.250 1.00 35.95  ? 193 PRO F CB  1 
ATOM   16232 C  CG  . PRO F 2 195 ? 233.060 288.321 289.254 1.00 37.12  ? 193 PRO F CG  1 
ATOM   16233 C  CD  . PRO F 2 195 ? 234.444 287.834 289.006 1.00 38.28  ? 193 PRO F CD  1 
ATOM   16234 N  N   . ILE F 2 196 ? 235.272 292.381 289.227 1.00 42.08  ? 194 ILE F N   1 
ATOM   16235 C  CA  . ILE F 2 196 ? 236.097 293.322 289.975 1.00 45.00  ? 194 ILE F CA  1 
ATOM   16236 C  C   . ILE F 2 196 ? 235.180 294.304 290.692 1.00 50.33  ? 194 ILE F C   1 
ATOM   16237 O  O   . ILE F 2 196 ? 234.527 295.144 290.054 1.00 47.41  ? 194 ILE F O   1 
ATOM   16238 C  CB  . ILE F 2 196 ? 237.097 294.058 289.074 1.00 44.70  ? 194 ILE F CB  1 
ATOM   16239 C  CG1 . ILE F 2 196 ? 238.015 293.058 288.370 1.00 35.98  ? 194 ILE F CG1 1 
ATOM   16240 C  CG2 . ILE F 2 196 ? 237.912 295.045 289.888 1.00 47.25  ? 194 ILE F CG2 1 
ATOM   16241 C  CD1 . ILE F 2 196 ? 238.673 293.608 287.127 1.00 32.40  ? 194 ILE F CD1 1 
ATOM   16242 N  N   . MET F 2 197 ? 235.157 294.214 292.020 1.00 51.24  ? 195 MET F N   1 
ATOM   16243 C  CA  . MET F 2 197 ? 234.392 295.130 292.852 1.00 52.91  ? 195 MET F CA  1 
ATOM   16244 C  C   . MET F 2 197 ? 235.204 296.396 293.097 1.00 59.57  ? 195 MET F C   1 
ATOM   16245 O  O   . MET F 2 197 ? 236.394 296.328 293.422 1.00 64.31  ? 195 MET F O   1 
ATOM   16246 C  CB  . MET F 2 197 ? 234.030 294.457 294.175 1.00 56.98  ? 195 MET F CB  1 
ATOM   16247 C  CG  . MET F 2 197 ? 233.457 295.383 295.226 1.00 69.09  ? 195 MET F CG  1 
ATOM   16248 S  SD  . MET F 2 197 ? 232.603 294.464 296.517 1.00 80.43  ? 195 MET F SD  1 
ATOM   16249 C  CE  . MET F 2 197 ? 233.996 293.866 297.470 1.00 69.25  ? 195 MET F CE  1 
ATOM   16250 N  N   . THR F 2 198 ? 234.560 297.550 292.941 1.00 65.91  ? 196 THR F N   1 
ATOM   16251 C  CA  . THR F 2 198 ? 235.264 298.826 292.986 1.00 72.53  ? 196 THR F CA  1 
ATOM   16252 C  C   . THR F 2 198 ? 234.744 299.716 294.108 1.00 79.75  ? 196 THR F C   1 
ATOM   16253 O  O   . THR F 2 198 ? 234.414 300.883 293.878 1.00 85.28  ? 196 THR F O   1 
ATOM   16254 C  CB  . THR F 2 198 ? 235.143 299.549 291.643 1.00 70.55  ? 196 THR F CB  1 
ATOM   16255 O  OG1 . THR F 2 198 ? 235.484 298.649 290.582 1.00 65.12  ? 196 THR F OG1 1 
ATOM   16256 C  CG2 . THR F 2 198 ? 236.076 300.748 291.599 1.00 77.96  ? 196 THR F CG2 1 
ATOM   16257 N  N   . GLY F 2 199 ? 234.659 299.178 295.321 1.00 84.01  ? 197 GLY F N   1 
ATOM   16258 C  CA  . GLY F 2 199 ? 234.207 299.964 296.451 1.00 97.89  ? 197 GLY F CA  1 
ATOM   16259 C  C   . GLY F 2 199 ? 235.152 301.096 296.804 1.00 107.93 ? 197 GLY F C   1 
ATOM   16260 O  O   . GLY F 2 199 ? 236.058 301.420 296.031 1.00 104.65 ? 197 GLY F O   1 
ATOM   16261 N  N   . GLN F 2 200 ? 234.954 301.704 297.971 1.00 111.90 ? 198 GLN F N   1 
ATOM   16262 C  CA  . GLN F 2 200 ? 235.759 302.835 298.412 1.00 118.72 ? 198 GLN F CA  1 
ATOM   16263 C  C   . GLN F 2 200 ? 236.816 302.361 299.400 1.00 123.17 ? 198 GLN F C   1 
ATOM   16264 O  O   . GLN F 2 200 ? 236.491 301.733 300.413 1.00 122.49 ? 198 GLN F O   1 
ATOM   16265 C  CB  . GLN F 2 200 ? 234.884 303.913 299.052 1.00 117.50 ? 198 GLN F CB  1 
ATOM   16266 C  CG  . GLN F 2 200 ? 235.643 305.165 299.463 1.00 119.37 ? 198 GLN F CG  1 
ATOM   16267 C  CD  . GLN F 2 200 ? 236.032 306.029 298.279 1.00 120.92 ? 198 GLN F CD  1 
ATOM   16268 O  OE1 . GLN F 2 200 ? 235.730 305.704 297.131 1.00 116.56 ? 198 GLN F OE1 1 
ATOM   16269 N  NE2 . GLN F 2 200 ? 236.706 307.140 298.554 1.00 121.91 ? 198 GLN F NE2 1 
ATOM   16270 N  N   . ASP F 2 201 ? 238.077 302.666 299.102 1.00 123.10 ? 199 ASP F N   1 
ATOM   16271 C  CA  . ASP F 2 201 ? 239.173 302.233 299.956 1.00 125.63 ? 199 ASP F CA  1 
ATOM   16272 C  C   . ASP F 2 201 ? 239.064 302.872 301.335 1.00 133.38 ? 199 ASP F C   1 
ATOM   16273 O  O   . ASP F 2 201 ? 238.729 304.052 301.469 1.00 132.82 ? 199 ASP F O   1 
ATOM   16274 C  CB  . ASP F 2 201 ? 240.514 302.590 299.316 1.00 123.87 ? 199 ASP F CB  1 
ATOM   16275 C  CG  . ASP F 2 201 ? 241.666 301.786 299.887 1.00 125.70 ? 199 ASP F CG  1 
ATOM   16276 O  OD1 . ASP F 2 201 ? 241.422 300.950 300.783 1.00 126.22 ? 199 ASP F OD1 1 
ATOM   16277 O  OD2 . ASP F 2 201 ? 242.815 301.990 299.441 1.00 123.57 ? 199 ASP F OD2 1 
ATOM   16278 N  N   . GLU F 2 202 ? 239.350 302.080 302.365 1.00 136.27 ? 200 GLU F N   1 
ATOM   16279 C  CA  . GLU F 2 202 ? 239.357 302.606 303.722 1.00 135.77 ? 200 GLU F CA  1 
ATOM   16280 C  C   . GLU F 2 202 ? 240.428 303.681 303.856 1.00 137.44 ? 200 GLU F C   1 
ATOM   16281 O  O   . GLU F 2 202 ? 241.508 303.582 303.268 1.00 136.74 ? 200 GLU F O   1 
ATOM   16282 C  CB  . GLU F 2 202 ? 239.602 301.482 304.728 1.00 133.90 ? 200 GLU F CB  1 
ATOM   16283 C  CG  . GLU F 2 202 ? 238.388 300.603 304.977 1.00 137.53 ? 200 GLU F CG  1 
ATOM   16284 C  CD  . GLU F 2 202 ? 238.199 300.268 306.442 1.00 140.72 ? 200 GLU F CD  1 
ATOM   16285 O  OE1 . GLU F 2 202 ? 239.206 299.972 307.120 1.00 139.80 ? 200 GLU F OE1 1 
ATOM   16286 O  OE2 . GLU F 2 202 ? 237.044 300.302 306.917 1.00 140.96 ? 200 GLU F OE2 1 
ATOM   16287 N  N   . PHE F 2 203 ? 240.121 304.716 304.633 1.00 137.57 ? 201 PHE F N   1 
ATOM   16288 C  CA  . PHE F 2 203 ? 240.946 305.895 304.849 1.00 140.17 ? 201 PHE F CA  1 
ATOM   16289 C  C   . PHE F 2 203 ? 240.882 306.841 303.648 1.00 142.00 ? 201 PHE F C   1 
ATOM   16290 O  O   . PHE F 2 203 ? 241.354 307.974 303.748 1.00 144.04 ? 201 PHE F O   1 
ATOM   16291 C  CB  . PHE F 2 203 ? 242.416 305.539 305.166 1.00 140.67 ? 201 PHE F CB  1 
ATOM   16292 C  CG  . PHE F 2 203 ? 243.418 306.576 304.736 1.00 144.40 ? 201 PHE F CG  1 
ATOM   16293 C  CD1 . PHE F 2 203 ? 243.784 307.602 305.592 1.00 144.86 ? 201 PHE F CD1 1 
ATOM   16294 C  CD2 . PHE F 2 203 ? 244.011 306.511 303.485 1.00 140.82 ? 201 PHE F CD2 1 
ATOM   16295 C  CE1 . PHE F 2 203 ? 244.709 308.551 305.203 1.00 145.17 ? 201 PHE F CE1 1 
ATOM   16296 C  CE2 . PHE F 2 203 ? 244.936 307.458 303.091 1.00 141.50 ? 201 PHE F CE2 1 
ATOM   16297 C  CZ  . PHE F 2 203 ? 245.286 308.479 303.951 1.00 145.22 ? 201 PHE F CZ  1 
ATOM   16298 N  N   . GLY F 2 204 ? 240.259 306.444 302.544 1.00 139.37 ? 202 GLY F N   1 
ATOM   16299 C  CA  . GLY F 2 204 ? 240.158 307.263 301.357 1.00 135.57 ? 202 GLY F CA  1 
ATOM   16300 C  C   . GLY F 2 204 ? 240.603 306.509 300.124 1.00 133.39 ? 202 GLY F C   1 
ATOM   16301 O  O   . GLY F 2 204 ? 241.029 305.357 300.180 1.00 132.17 ? 202 GLY F O   1 
ATOM   16302 N  N   . GLU F 2 205 ? 240.490 307.188 298.983 1.00 131.72 ? 203 GLU F N   1 
ATOM   16303 C  CA  . GLU F 2 205 ? 240.911 306.616 297.709 1.00 130.04 ? 203 GLU F CA  1 
ATOM   16304 C  C   . GLU F 2 205 ? 239.997 305.470 297.295 1.00 125.95 ? 203 GLU F C   1 
ATOM   16305 O  O   . GLU F 2 205 ? 239.208 304.971 298.104 1.00 126.82 ? 203 GLU F O   1 
ATOM   16306 C  CB  . GLU F 2 205 ? 242.362 306.135 297.796 1.00 128.16 ? 203 GLU F CB  1 
ATOM   16307 C  CG  . GLU F 2 205 ? 243.033 305.916 296.450 1.00 127.15 ? 203 GLU F CG  1 
ATOM   16308 C  CD  . GLU F 2 205 ? 242.724 307.019 295.458 1.00 128.10 ? 203 GLU F CD  1 
ATOM   16309 O  OE1 . GLU F 2 205 ? 241.638 306.981 294.842 1.00 126.56 ? 203 GLU F OE1 1 
ATOM   16310 O  OE2 . GLU F 2 205 ? 243.568 307.924 295.293 1.00 126.87 ? 203 GLU F OE2 1 
ATOM   16311 N  N   . VAL F 2 206 ? 240.092 305.050 296.037 1.00 120.22 ? 204 VAL F N   1 
ATOM   16312 C  CA  . VAL F 2 206 ? 239.327 303.921 295.529 1.00 118.23 ? 204 VAL F CA  1 
ATOM   16313 C  C   . VAL F 2 206 ? 240.249 302.713 295.433 1.00 113.28 ? 204 VAL F C   1 
ATOM   16314 O  O   . VAL F 2 206 ? 241.478 302.830 295.427 1.00 110.98 ? 204 VAL F O   1 
ATOM   16315 C  CB  . VAL F 2 206 ? 238.673 304.223 294.166 1.00 115.19 ? 204 VAL F CB  1 
ATOM   16316 C  CG1 . VAL F 2 206 ? 239.645 303.926 293.033 1.00 108.05 ? 204 VAL F CG1 1 
ATOM   16317 C  CG2 . VAL F 2 206 ? 237.392 303.418 294.006 1.00 105.85 ? 204 VAL F CG2 1 
ATOM   16318 N  N   . ARG F 2 207 ? 239.639 301.532 295.355 1.00 104.97 ? 205 ARG F N   1 
ATOM   16319 C  CA  . ARG F 2 207 ? 240.399 300.288 295.328 1.00 94.98  ? 205 ARG F CA  1 
ATOM   16320 C  C   . ARG F 2 207 ? 239.595 299.223 294.599 1.00 87.67  ? 205 ARG F C   1 
ATOM   16321 O  O   . ARG F 2 207 ? 238.458 298.932 294.983 1.00 86.35  ? 205 ARG F O   1 
ATOM   16322 C  CB  . ARG F 2 207 ? 240.743 299.837 296.750 1.00 100.56 ? 205 ARG F CB  1 
ATOM   16323 C  CG  . ARG F 2 207 ? 241.345 298.451 296.844 1.00 96.86  ? 205 ARG F CG  1 
ATOM   16324 C  CD  . ARG F 2 207 ? 240.482 297.546 297.703 1.00 97.01  ? 205 ARG F CD  1 
ATOM   16325 N  NE  . ARG F 2 207 ? 240.086 298.185 298.952 1.00 107.79 ? 205 ARG F NE  1 
ATOM   16326 C  CZ  . ARG F 2 207 ? 240.489 297.792 300.153 1.00 114.69 ? 205 ARG F CZ  1 
ATOM   16327 N  NH1 . ARG F 2 207 ? 241.296 296.755 300.307 1.00 109.35 ? 205 ARG F NH1 1 
ATOM   16328 N  NH2 . ARG F 2 207 ? 240.070 298.455 301.228 1.00 120.33 ? 205 ARG F NH2 1 
ATOM   16329 N  N   . ASN F 2 208 ? 240.184 298.650 293.552 1.00 81.25  ? 206 ASN F N   1 
ATOM   16330 C  CA  . ASN F 2 208 ? 239.558 297.577 292.791 1.00 74.67  ? 206 ASN F CA  1 
ATOM   16331 C  C   . ASN F 2 208 ? 240.027 296.230 293.324 1.00 71.31  ? 206 ASN F C   1 
ATOM   16332 O  O   . ASN F 2 208 ? 241.231 295.998 293.468 1.00 72.04  ? 206 ASN F O   1 
ATOM   16333 C  CB  . ASN F 2 208 ? 239.892 297.702 291.305 1.00 72.36  ? 206 ASN F CB  1 
ATOM   16334 C  CG  . ASN F 2 208 ? 239.748 299.119 290.795 1.00 78.85  ? 206 ASN F CG  1 
ATOM   16335 O  OD1 . ASN F 2 208 ? 238.812 299.828 291.160 1.00 84.87  ? 206 ASN F OD1 1 
ATOM   16336 N  ND2 . ASN F 2 208 ? 240.677 299.541 289.944 1.00 73.76  ? 206 ASN F ND2 1 
ATOM   16337 N  N   . GLN F 2 209 ? 239.078 295.348 293.611 1.00 66.31  ? 207 GLN F N   1 
ATOM   16338 C  CA  . GLN F 2 209 ? 239.379 294.050 294.214 1.00 62.33  ? 207 GLN F CA  1 
ATOM   16339 C  C   . GLN F 2 209 ? 238.813 292.918 293.373 1.00 61.35  ? 207 GLN F C   1 
ATOM   16340 O  O   . GLN F 2 209 ? 237.579 292.777 293.281 1.00 60.63  ? 207 GLN F O   1 
ATOM   16341 C  CB  . GLN F 2 209 ? 238.810 293.980 295.630 1.00 65.99  ? 207 GLN F CB  1 
ATOM   16342 C  CG  . GLN F 2 209 ? 238.800 295.305 296.353 1.00 75.18  ? 207 GLN F CG  1 
ATOM   16343 C  CD  . GLN F 2 209 ? 238.150 295.216 297.718 1.00 84.99  ? 207 GLN F CD  1 
ATOM   16344 O  OE1 . GLN F 2 209 ? 238.227 294.187 298.389 1.00 79.20  ? 207 GLN F OE1 1 
ATOM   16345 N  NE2 . GLN F 2 209 ? 237.504 296.297 298.136 1.00 90.53  ? 207 GLN F NE2 1 
ATOM   16346 N  N   . PRO F 2 210 ? 239.647 292.091 292.744 1.00 59.28  ? 208 PRO F N   1 
ATOM   16347 C  CA  . PRO F 2 210 ? 239.127 290.876 292.110 1.00 54.21  ? 208 PRO F CA  1 
ATOM   16348 C  C   . PRO F 2 210 ? 238.493 289.960 293.145 1.00 53.54  ? 208 PRO F C   1 
ATOM   16349 O  O   . PRO F 2 210 ? 238.949 289.866 294.287 1.00 54.25  ? 208 PRO F O   1 
ATOM   16350 C  CB  . PRO F 2 210 ? 240.372 290.242 291.479 1.00 46.30  ? 208 PRO F CB  1 
ATOM   16351 C  CG  . PRO F 2 210 ? 241.336 291.372 291.327 1.00 48.37  ? 208 PRO F CG  1 
ATOM   16352 C  CD  . PRO F 2 210 ? 241.087 292.266 292.503 1.00 54.28  ? 208 PRO F CD  1 
ATOM   16353 N  N   . LEU F 2 211 ? 237.426 289.278 292.733 1.00 50.51  ? 209 LEU F N   1 
ATOM   16354 C  CA  . LEU F 2 211 ? 236.646 288.439 293.637 1.00 51.75  ? 209 LEU F CA  1 
ATOM   16355 C  C   . LEU F 2 211 ? 237.009 286.963 293.509 1.00 53.36  ? 209 LEU F C   1 
ATOM   16356 O  O   . LEU F 2 211 ? 237.403 286.330 294.492 1.00 57.19  ? 209 LEU F O   1 
ATOM   16357 C  CB  . LEU F 2 211 ? 235.148 288.650 293.379 1.00 50.63  ? 209 LEU F CB  1 
ATOM   16358 C  CG  . LEU F 2 211 ? 234.615 290.069 293.602 1.00 52.89  ? 209 LEU F CG  1 
ATOM   16359 C  CD1 . LEU F 2 211 ? 233.112 290.118 293.385 1.00 50.85  ? 209 LEU F CD1 1 
ATOM   16360 C  CD2 . LEU F 2 211 ? 234.971 290.568 294.993 1.00 55.24  ? 209 LEU F CD2 1 
ATOM   16361 N  N   . PHE F 2 212 ? 236.889 286.402 292.310 1.00 50.18  ? 210 PHE F N   1 
ATOM   16362 C  CA  . PHE F 2 212 ? 237.173 284.989 292.097 1.00 46.88  ? 210 PHE F CA  1 
ATOM   16363 C  C   . PHE F 2 212 ? 237.196 284.723 290.599 1.00 47.73  ? 210 PHE F C   1 
ATOM   16364 O  O   . PHE F 2 212 ? 236.841 285.583 289.790 1.00 49.56  ? 210 PHE F O   1 
ATOM   16365 C  CB  . PHE F 2 212 ? 236.144 284.097 292.798 1.00 47.34  ? 210 PHE F CB  1 
ATOM   16366 C  CG  . PHE F 2 212 ? 234.730 284.593 292.686 1.00 46.77  ? 210 PHE F CG  1 
ATOM   16367 C  CD1 . PHE F 2 212 ? 234.062 284.565 291.474 1.00 44.42  ? 210 PHE F CD1 1 
ATOM   16368 C  CD2 . PHE F 2 212 ? 234.068 285.090 293.796 1.00 49.17  ? 210 PHE F CD2 1 
ATOM   16369 C  CE1 . PHE F 2 212 ? 232.763 285.022 291.373 1.00 43.66  ? 210 PHE F CE1 1 
ATOM   16370 C  CE2 . PHE F 2 212 ? 232.770 285.546 293.700 1.00 45.92  ? 210 PHE F CE2 1 
ATOM   16371 C  CZ  . PHE F 2 212 ? 232.117 285.512 292.487 1.00 43.69  ? 210 PHE F CZ  1 
ATOM   16372 N  N   . TRP F 2 213 ? 237.618 283.514 290.241 1.00 43.76  ? 211 TRP F N   1 
ATOM   16373 C  CA  . TRP F 2 213 ? 237.694 283.081 288.854 1.00 41.14  ? 211 TRP F CA  1 
ATOM   16374 C  C   . TRP F 2 213 ? 236.553 282.118 288.565 1.00 42.94  ? 211 TRP F C   1 
ATOM   16375 O  O   . TRP F 2 213 ? 236.363 281.137 289.290 1.00 46.27  ? 211 TRP F O   1 
ATOM   16376 C  CB  . TRP F 2 213 ? 239.037 282.409 288.559 1.00 41.96  ? 211 TRP F CB  1 
ATOM   16377 C  CG  . TRP F 2 213 ? 240.138 283.373 288.251 1.00 42.32  ? 211 TRP F CG  1 
ATOM   16378 C  CD1 . TRP F 2 213 ? 241.213 283.660 289.035 1.00 43.99  ? 211 TRP F CD1 1 
ATOM   16379 C  CD2 . TRP F 2 213 ? 240.272 284.178 287.074 1.00 40.55  ? 211 TRP F CD2 1 
ATOM   16380 N  NE1 . TRP F 2 213 ? 242.011 284.592 288.421 1.00 43.70  ? 211 TRP F NE1 1 
ATOM   16381 C  CE2 . TRP F 2 213 ? 241.455 284.927 287.215 1.00 41.28  ? 211 TRP F CE2 1 
ATOM   16382 C  CE3 . TRP F 2 213 ? 239.508 284.337 285.915 1.00 38.77  ? 211 TRP F CE3 1 
ATOM   16383 C  CZ2 . TRP F 2 213 ? 241.892 285.822 286.242 1.00 36.67  ? 211 TRP F CZ2 1 
ATOM   16384 C  CZ3 . TRP F 2 213 ? 239.943 285.226 284.951 1.00 32.53  ? 211 TRP F CZ3 1 
ATOM   16385 C  CH2 . TRP F 2 213 ? 241.123 285.957 285.120 1.00 34.00  ? 211 TRP F CH2 1 
ATOM   16386 N  N   . ILE F 2 214 ? 235.800 282.400 287.509 1.00 43.98  ? 212 ILE F N   1 
ATOM   16387 C  CA  . ILE F 2 214 ? 234.691 281.560 287.077 1.00 39.30  ? 212 ILE F CA  1 
ATOM   16388 C  C   . ILE F 2 214 ? 235.086 280.921 285.747 1.00 41.75  ? 212 ILE F C   1 
ATOM   16389 O  O   . ILE F 2 214 ? 235.124 281.613 284.720 1.00 44.66  ? 212 ILE F O   1 
ATOM   16390 C  CB  . ILE F 2 214 ? 233.390 282.363 286.943 1.00 36.58  ? 212 ILE F CB  1 
ATOM   16391 C  CG1 . ILE F 2 214 ? 233.077 283.092 288.249 1.00 40.85  ? 212 ILE F CG1 1 
ATOM   16392 C  CG2 . ILE F 2 214 ? 232.237 281.454 286.551 1.00 39.32  ? 212 ILE F CG2 1 
ATOM   16393 C  CD1 . ILE F 2 214 ? 232.462 284.453 288.051 1.00 38.26  ? 212 ILE F CD1 1 
ATOM   16394 N  N   . PRO F 2 215 ? 235.401 279.627 285.713 1.00 43.68  ? 213 PRO F N   1 
ATOM   16395 C  CA  . PRO F 2 215 ? 235.644 278.976 284.422 1.00 39.72  ? 213 PRO F CA  1 
ATOM   16396 C  C   . PRO F 2 215 ? 234.428 279.128 283.523 1.00 41.06  ? 213 PRO F C   1 
ATOM   16397 O  O   . PRO F 2 215 ? 233.286 278.969 283.960 1.00 43.20  ? 213 PRO F O   1 
ATOM   16398 C  CB  . PRO F 2 215 ? 235.896 277.512 284.798 1.00 42.47  ? 213 PRO F CB  1 
ATOM   16399 C  CG  . PRO F 2 215 ? 236.263 277.541 286.243 1.00 41.75  ? 213 PRO F CG  1 
ATOM   16400 C  CD  . PRO F 2 215 ? 235.512 278.687 286.839 1.00 42.28  ? 213 PRO F CD  1 
ATOM   16401 N  N   . TYR F 2 216 ? 234.681 279.441 282.252 1.00 40.62  ? 214 TYR F N   1 
ATOM   16402 C  CA  . TYR F 2 216 ? 233.581 279.778 281.357 1.00 38.06  ? 214 TYR F CA  1 
ATOM   16403 C  C   . TYR F 2 216 ? 232.662 278.588 281.112 1.00 39.68  ? 214 TYR F C   1 
ATOM   16404 O  O   . TYR F 2 216 ? 231.458 278.773 280.915 1.00 42.37  ? 214 TYR F O   1 
ATOM   16405 C  CB  . TYR F 2 216 ? 234.114 280.318 280.032 1.00 34.02  ? 214 TYR F CB  1 
ATOM   16406 C  CG  . TYR F 2 216 ? 233.057 281.031 279.226 1.00 38.80  ? 214 TYR F CG  1 
ATOM   16407 C  CD1 . TYR F 2 216 ? 232.569 282.266 279.628 1.00 37.82  ? 214 TYR F CD1 1 
ATOM   16408 C  CD2 . TYR F 2 216 ? 232.533 280.464 278.074 1.00 37.88  ? 214 TYR F CD2 1 
ATOM   16409 C  CE1 . TYR F 2 216 ? 231.598 282.920 278.902 1.00 37.12  ? 214 TYR F CE1 1 
ATOM   16410 C  CE2 . TYR F 2 216 ? 231.561 281.110 277.342 1.00 40.24  ? 214 TYR F CE2 1 
ATOM   16411 C  CZ  . TYR F 2 216 ? 231.096 282.337 277.759 1.00 40.82  ? 214 TYR F CZ  1 
ATOM   16412 O  OH  . TYR F 2 216 ? 230.127 282.984 277.029 1.00 39.54  ? 214 TYR F OH  1 
ATOM   16413 N  N   . GLU F 2 217 ? 233.204 277.369 281.107 1.00 41.20  ? 215 GLU F N   1 
ATOM   16414 C  CA  . GLU F 2 217 ? 232.360 276.195 280.913 1.00 42.90  ? 215 GLU F CA  1 
ATOM   16415 C  C   . GLU F 2 217 ? 231.359 276.031 282.049 1.00 44.01  ? 215 GLU F C   1 
ATOM   16416 O  O   . GLU F 2 217 ? 230.266 275.493 281.841 1.00 43.95  ? 215 GLU F O   1 
ATOM   16417 C  CB  . GLU F 2 217 ? 233.224 274.941 280.781 1.00 41.77  ? 215 GLU F CB  1 
ATOM   16418 C  CG  . GLU F 2 217 ? 233.979 274.563 282.045 1.00 50.27  ? 215 GLU F CG  1 
ATOM   16419 C  CD  . GLU F 2 217 ? 235.450 274.923 281.976 1.00 60.17  ? 215 GLU F CD  1 
ATOM   16420 O  OE1 . GLU F 2 217 ? 235.764 276.120 281.801 1.00 57.03  ? 215 GLU F OE1 1 
ATOM   16421 O  OE2 . GLU F 2 217 ? 236.293 274.010 282.092 1.00 59.93  ? 215 GLU F OE2 1 
ATOM   16422 N  N   . ASN F 2 218 ? 231.712 276.486 283.252 1.00 43.59  ? 216 ASN F N   1 
ATOM   16423 C  CA  . ASN F 2 218 ? 230.806 276.353 284.388 1.00 41.55  ? 216 ASN F CA  1 
ATOM   16424 C  C   . ASN F 2 218 ? 229.602 277.276 284.254 1.00 44.90  ? 216 ASN F C   1 
ATOM   16425 O  O   . ASN F 2 218 ? 228.473 276.884 284.569 1.00 55.49  ? 216 ASN F O   1 
ATOM   16426 C  CB  . ASN F 2 218 ? 231.557 276.637 285.687 1.00 44.34  ? 216 ASN F CB  1 
ATOM   16427 C  CG  . ASN F 2 218 ? 232.567 275.561 286.022 1.00 48.78  ? 216 ASN F CG  1 
ATOM   16428 O  OD1 . ASN F 2 218 ? 232.875 274.705 285.194 1.00 50.97  ? 216 ASN F OD1 1 
ATOM   16429 N  ND2 . ASN F 2 218 ? 233.093 275.603 287.240 1.00 52.50  ? 216 ASN F ND2 1 
ATOM   16430 N  N   . ILE F 2 219 ? 229.821 278.509 283.789 1.00 41.91  ? 217 ILE F N   1 
ATOM   16431 C  CA  . ILE F 2 219 ? 228.746 279.495 283.721 1.00 41.78  ? 217 ILE F CA  1 
ATOM   16432 C  C   . ILE F 2 219 ? 228.053 279.532 282.366 1.00 45.02  ? 217 ILE F C   1 
ATOM   16433 O  O   . ILE F 2 219 ? 226.991 280.159 282.244 1.00 46.61  ? 217 ILE F O   1 
ATOM   16434 C  CB  . ILE F 2 219 ? 229.282 280.899 284.068 1.00 43.86  ? 217 ILE F CB  1 
ATOM   16435 C  CG1 . ILE F 2 219 ? 228.127 281.891 284.204 1.00 43.15  ? 217 ILE F CG1 1 
ATOM   16436 C  CG2 . ILE F 2 219 ? 230.283 281.365 283.023 1.00 37.71  ? 217 ILE F CG2 1 
ATOM   16437 C  CD1 . ILE F 2 219 ? 227.343 281.729 285.483 1.00 49.46  ? 217 ILE F CD1 1 
ATOM   16438 N  N   . ARG F 2 220 ? 228.607 278.872 281.351 1.00 44.04  ? 218 ARG F N   1 
ATOM   16439 C  CA  . ARG F 2 220 ? 228.035 278.961 280.009 1.00 46.48  ? 218 ARG F CA  1 
ATOM   16440 C  C   . ARG F 2 220 ? 226.588 278.496 279.948 1.00 50.32  ? 218 ARG F C   1 
ATOM   16441 O  O   . ARG F 2 220 ? 225.750 279.228 279.395 1.00 50.18  ? 218 ARG F O   1 
ATOM   16442 C  CB  . ARG F 2 220 ? 228.906 278.167 279.033 1.00 47.40  ? 218 ARG F CB  1 
ATOM   16443 C  CG  . ARG F 2 220 ? 228.638 278.479 277.575 1.00 45.25  ? 218 ARG F CG  1 
ATOM   16444 C  CD  . ARG F 2 220 ? 228.629 277.216 276.738 1.00 51.91  ? 218 ARG F CD  1 
ATOM   16445 N  NE  . ARG F 2 220 ? 227.272 276.774 276.436 1.00 64.94  ? 218 ARG F NE  1 
ATOM   16446 C  CZ  . ARG F 2 220 ? 226.637 275.807 277.083 1.00 64.56  ? 218 ARG F CZ  1 
ATOM   16447 N  NH1 . ARG F 2 220 ? 227.208 275.150 278.079 1.00 59.68  ? 218 ARG F NH1 1 
ATOM   16448 N  NH2 . ARG F 2 220 ? 225.397 275.490 276.721 1.00 54.83  ? 218 ARG F NH2 1 
ATOM   16449 N  N   . PRO F 2 221 ? 226.223 277.322 280.467 1.00 51.69  ? 219 PRO F N   1 
ATOM   16450 C  CA  . PRO F 2 221 ? 224.822 276.887 280.354 1.00 48.08  ? 219 PRO F CA  1 
ATOM   16451 C  C   . PRO F 2 221 ? 223.837 277.847 280.995 1.00 48.86  ? 219 PRO F C   1 
ATOM   16452 O  O   . PRO F 2 221 ? 222.706 277.975 280.511 1.00 52.27  ? 219 PRO F O   1 
ATOM   16453 C  CB  . PRO F 2 221 ? 224.818 275.522 281.060 1.00 48.63  ? 219 PRO F CB  1 
ATOM   16454 C  CG  . PRO F 2 221 ? 226.093 275.479 281.851 1.00 46.57  ? 219 PRO F CG  1 
ATOM   16455 C  CD  . PRO F 2 221 ? 227.073 276.285 281.072 1.00 44.95  ? 219 PRO F CD  1 
ATOM   16456 N  N   . TYR F 2 222 ? 224.230 278.525 282.074 1.00 49.01  ? 220 TYR F N   1 
ATOM   16457 C  CA  . TYR F 2 222 ? 223.307 279.408 282.775 1.00 50.69  ? 220 TYR F CA  1 
ATOM   16458 C  C   . TYR F 2 222 ? 223.118 280.740 282.061 1.00 51.52  ? 220 TYR F C   1 
ATOM   16459 O  O   . TYR F 2 222 ? 222.023 281.310 282.107 1.00 55.34  ? 220 TYR F O   1 
ATOM   16460 C  CB  . TYR F 2 222 ? 223.796 279.642 284.203 1.00 47.59  ? 220 TYR F CB  1 
ATOM   16461 C  CG  . TYR F 2 222 ? 223.692 278.414 285.074 1.00 53.43  ? 220 TYR F CG  1 
ATOM   16462 C  CD1 . TYR F 2 222 ? 222.464 277.984 285.555 1.00 55.04  ? 220 TYR F CD1 1 
ATOM   16463 C  CD2 . TYR F 2 222 ? 224.820 277.680 285.408 1.00 53.46  ? 220 TYR F CD2 1 
ATOM   16464 C  CE1 . TYR F 2 222 ? 222.363 276.861 286.347 1.00 57.24  ? 220 TYR F CE1 1 
ATOM   16465 C  CE2 . TYR F 2 222 ? 224.730 276.554 286.201 1.00 57.39  ? 220 TYR F CE2 1 
ATOM   16466 C  CZ  . TYR F 2 222 ? 223.498 276.150 286.667 1.00 62.77  ? 220 TYR F CZ  1 
ATOM   16467 O  OH  . TYR F 2 222 ? 223.399 275.029 287.458 1.00 65.16  ? 220 TYR F OH  1 
ATOM   16468 N  N   . ILE F 2 223 ? 224.161 281.253 281.401 1.00 46.70  ? 221 ILE F N   1 
ATOM   16469 C  CA  . ILE F 2 223 ? 224.057 282.541 280.721 1.00 45.98  ? 221 ILE F CA  1 
ATOM   16470 C  C   . ILE F 2 223 ? 223.596 282.410 279.278 1.00 47.73  ? 221 ILE F C   1 
ATOM   16471 O  O   . ILE F 2 223 ? 223.372 283.434 278.616 1.00 48.74  ? 221 ILE F O   1 
ATOM   16472 C  CB  . ILE F 2 223 ? 225.395 283.305 280.756 1.00 39.72  ? 221 ILE F CB  1 
ATOM   16473 C  CG1 . ILE F 2 223 ? 226.548 282.391 280.344 1.00 41.65  ? 221 ILE F CG1 1 
ATOM   16474 C  CG2 . ILE F 2 223 ? 225.633 283.890 282.134 1.00 41.82  ? 221 ILE F CG2 1 
ATOM   16475 C  CD1 . ILE F 2 223 ? 227.795 283.137 279.949 1.00 35.86  ? 221 ILE F CD1 1 
ATOM   16476 N  N   . ALA F 2 224 ? 223.447 281.189 278.768 1.00 45.55  ? 222 ALA F N   1 
ATOM   16477 C  CA  . ALA F 2 224 ? 222.916 280.990 277.429 1.00 44.34  ? 222 ALA F CA  1 
ATOM   16478 C  C   . ALA F 2 224 ? 221.398 281.083 277.385 1.00 52.58  ? 222 ALA F C   1 
ATOM   16479 O  O   . ALA F 2 224 ? 220.819 281.023 276.295 1.00 54.73  ? 222 ALA F O   1 
ATOM   16480 C  CB  . ALA F 2 224 ? 223.368 279.636 276.879 1.00 40.75  ? 222 ALA F CB  1 
ATOM   16481 N  N   . ARG F 2 225 ? 220.745 281.224 278.539 1.00 54.90  ? 223 ARG F N   1 
ATOM   16482 C  CA  . ARG F 2 225 ? 219.300 281.367 278.610 1.00 59.43  ? 223 ARG F CA  1 
ATOM   16483 C  C   . ARG F 2 225 ? 218.844 282.776 278.956 1.00 58.95  ? 223 ARG F C   1 
ATOM   16484 O  O   . ARG F 2 225 ? 217.680 283.106 278.713 1.00 57.43  ? 223 ARG F O   1 
ATOM   16485 C  CB  . ARG F 2 225 ? 218.722 280.393 279.647 1.00 67.57  ? 223 ARG F CB  1 
ATOM   16486 C  CG  . ARG F 2 225 ? 218.658 278.949 279.179 1.00 71.13  ? 223 ARG F CG  1 
ATOM   16487 C  CD  . ARG F 2 225 ? 217.800 278.101 280.107 1.00 74.99  ? 223 ARG F CD  1 
ATOM   16488 N  NE  . ARG F 2 225 ? 218.601 277.367 281.080 1.00 80.37  ? 223 ARG F NE  1 
ATOM   16489 C  CZ  . ARG F 2 225 ? 219.246 277.922 282.097 1.00 74.77  ? 223 ARG F CZ  1 
ATOM   16490 N  NH1 . ARG F 2 225 ? 219.194 279.225 282.320 1.00 70.46  ? 223 ARG F NH1 1 
ATOM   16491 N  NH2 . ARG F 2 225 ? 219.957 277.150 282.914 1.00 66.13  ? 223 ARG F NH2 1 
ATOM   16492 N  N   . GLU F 2 226 ? 219.724 283.609 279.506 1.00 62.69  ? 224 GLU F N   1 
ATOM   16493 C  CA  . GLU F 2 226 ? 219.364 284.964 279.912 1.00 63.70  ? 224 GLU F CA  1 
ATOM   16494 C  C   . GLU F 2 226 ? 219.396 285.879 278.694 1.00 53.85  ? 224 GLU F C   1 
ATOM   16495 O  O   . GLU F 2 226 ? 220.467 286.151 278.141 1.00 48.97  ? 224 GLU F O   1 
ATOM   16496 C  CB  . GLU F 2 226 ? 220.314 285.464 280.996 1.00 61.72  ? 224 GLU F CB  1 
ATOM   16497 C  CG  . GLU F 2 226 ? 219.991 284.969 282.399 1.00 67.93  ? 224 GLU F CG  1 
ATOM   16498 C  CD  . GLU F 2 226 ? 218.527 285.136 282.765 1.00 77.83  ? 224 GLU F CD  1 
ATOM   16499 O  OE1 . GLU F 2 226 ? 217.822 285.917 282.091 1.00 75.77  ? 224 GLU F OE1 1 
ATOM   16500 O  OE2 . GLU F 2 226 ? 218.080 284.486 283.734 1.00 74.67  ? 224 GLU F OE2 1 
ATOM   16501 N  N   . ARG F 2 227 ? 218.227 286.358 278.277 1.00 49.13  ? 225 ARG F N   1 
ATOM   16502 C  CA  . ARG F 2 227 ? 218.142 287.273 277.148 1.00 45.28  ? 225 ARG F CA  1 
ATOM   16503 C  C   . ARG F 2 227 ? 218.368 288.703 277.621 1.00 43.57  ? 225 ARG F C   1 
ATOM   16504 O  O   . ARG F 2 227 ? 217.779 289.140 278.614 1.00 45.83  ? 225 ARG F O   1 
ATOM   16505 C  CB  . ARG F 2 227 ? 216.786 287.147 276.457 1.00 43.42  ? 225 ARG F CB  1 
ATOM   16506 C  CG  . ARG F 2 227 ? 216.596 285.836 275.717 1.00 44.94  ? 225 ARG F CG  1 
ATOM   16507 C  CD  . ARG F 2 227 ? 215.859 286.037 274.408 1.00 50.44  ? 225 ARG F CD  1 
ATOM   16508 N  NE  . ARG F 2 227 ? 216.767 286.044 273.267 1.00 53.90  ? 225 ARG F NE  1 
ATOM   16509 C  CZ  . ARG F 2 227 ? 217.388 284.971 272.797 1.00 55.93  ? 225 ARG F CZ  1 
ATOM   16510 N  NH1 . ARG F 2 227 ? 217.214 283.778 273.343 1.00 59.32  ? 225 ARG F NH1 1 
ATOM   16511 N  NH2 . ARG F 2 227 ? 218.204 285.098 271.755 1.00 50.62  ? 225 ARG F NH2 1 
ATOM   16512 N  N   . VAL F 2 228 ? 219.223 289.431 276.904 1.00 42.74  ? 226 VAL F N   1 
ATOM   16513 C  CA  . VAL F 2 228 ? 219.611 290.786 277.262 1.00 38.71  ? 226 VAL F CA  1 
ATOM   16514 C  C   . VAL F 2 228 ? 219.493 291.672 276.029 1.00 35.92  ? 226 VAL F C   1 
ATOM   16515 O  O   . VAL F 2 228 ? 219.297 291.201 274.910 1.00 39.92  ? 226 VAL F O   1 
ATOM   16516 C  CB  . VAL F 2 228 ? 221.041 290.848 277.839 1.00 39.04  ? 226 VAL F CB  1 
ATOM   16517 C  CG1 . VAL F 2 228 ? 221.128 290.043 279.121 1.00 39.70  ? 226 VAL F CG1 1 
ATOM   16518 C  CG2 . VAL F 2 228 ? 222.050 290.341 276.818 1.00 34.05  ? 226 VAL F CG2 1 
ATOM   16519 N  N   . MET F 2 229 ? 219.610 292.976 276.255 1.00 38.10  ? 227 MET F N   1 
ATOM   16520 C  CA  . MET F 2 229 ? 219.641 293.966 275.189 1.00 36.83  ? 227 MET F CA  1 
ATOM   16521 C  C   . MET F 2 229 ? 221.064 294.483 275.026 1.00 35.50  ? 227 MET F C   1 
ATOM   16522 O  O   . MET F 2 229 ? 221.744 294.780 276.013 1.00 40.89  ? 227 MET F O   1 
ATOM   16523 C  CB  . MET F 2 229 ? 218.673 295.115 275.484 1.00 32.85  ? 227 MET F CB  1 
ATOM   16524 C  CG  . MET F 2 229 ? 219.313 296.348 276.089 1.00 31.99  ? 227 MET F CG  1 
ATOM   16525 S  SD  . MET F 2 229 ? 218.110 297.371 276.956 1.00 43.70  ? 227 MET F SD  1 
ATOM   16526 C  CE  . MET F 2 229 ? 219.187 298.431 277.916 1.00 34.91  ? 227 MET F CE  1 
ATOM   16527 N  N   . LEU F 2 230 ? 221.514 294.582 273.777 1.00 35.65  ? 228 LEU F N   1 
ATOM   16528 C  CA  . LEU F 2 230 ? 222.904 294.900 273.473 1.00 34.36  ? 228 LEU F CA  1 
ATOM   16529 C  C   . LEU F 2 230 ? 223.156 296.382 273.237 1.00 36.53  ? 228 LEU F C   1 
ATOM   16530 O  O   . LEU F 2 230 ? 224.298 296.760 272.960 1.00 38.55  ? 228 LEU F O   1 
ATOM   16531 C  CB  . LEU F 2 230 ? 223.366 294.115 272.241 1.00 40.27  ? 228 LEU F CB  1 
ATOM   16532 C  CG  . LEU F 2 230 ? 223.335 292.591 272.329 1.00 47.28  ? 228 LEU F CG  1 
ATOM   16533 C  CD1 . LEU F 2 230 ? 223.598 291.984 270.962 1.00 43.88  ? 228 LEU F CD1 1 
ATOM   16534 C  CD2 . LEU F 2 230 ? 224.345 292.090 273.348 1.00 38.86  ? 228 LEU F CD2 1 
ATOM   16535 N  N   . SER F 2 231 ? 222.137 297.230 273.335 1.00 39.56  ? 229 SER F N   1 
ATOM   16536 C  CA  . SER F 2 231 ? 222.312 298.636 273.011 1.00 33.93  ? 229 SER F CA  1 
ATOM   16537 C  C   . SER F 2 231 ? 221.312 299.471 273.793 1.00 33.42  ? 229 SER F C   1 
ATOM   16538 O  O   . SER F 2 231 ? 220.281 298.974 274.253 1.00 37.73  ? 229 SER F O   1 
ATOM   16539 C  CB  . SER F 2 231 ? 222.152 298.885 271.505 1.00 35.53  ? 229 SER F CB  1 
ATOM   16540 O  OG  . SER F 2 231 ? 222.659 300.154 271.134 1.00 40.23  ? 229 SER F OG  1 
ATOM   16541 N  N   . SER F 2 232 ? 221.640 300.753 273.946 1.00 33.40  ? 230 SER F N   1 
ATOM   16542 C  CA  . SER F 2 232 ? 220.696 301.713 274.500 1.00 35.09  ? 230 SER F CA  1 
ATOM   16543 C  C   . SER F 2 232 ? 219.752 302.266 273.442 1.00 35.10  ? 230 SER F C   1 
ATOM   16544 O  O   . SER F 2 232 ? 218.651 302.711 273.782 1.00 35.71  ? 230 SER F O   1 
ATOM   16545 C  CB  . SER F 2 232 ? 221.444 302.865 275.173 1.00 37.10  ? 230 SER F CB  1 
ATOM   16546 O  OG  . SER F 2 232 ? 222.177 302.412 276.295 1.00 43.81  ? 230 SER F OG  1 
ATOM   16547 N  N   . LEU F 2 233 ? 220.160 302.246 272.174 1.00 36.63  ? 231 LEU F N   1 
ATOM   16548 C  CA  . LEU F 2 233 ? 219.317 302.703 271.079 1.00 32.91  ? 231 LEU F CA  1 
ATOM   16549 C  C   . LEU F 2 233 ? 218.307 301.655 270.630 1.00 32.53  ? 231 LEU F C   1 
ATOM   16550 O  O   . LEU F 2 233 ? 217.391 301.988 269.872 1.00 39.84  ? 231 LEU F O   1 
ATOM   16551 C  CB  . LEU F 2 233 ? 220.188 303.123 269.893 1.00 36.07  ? 231 LEU F CB  1 
ATOM   16552 C  CG  . LEU F 2 233 ? 221.030 304.385 270.088 1.00 35.36  ? 231 LEU F CG  1 
ATOM   16553 C  CD1 . LEU F 2 233 ? 221.831 304.695 268.835 1.00 44.14  ? 231 LEU F CD1 1 
ATOM   16554 C  CD2 . LEU F 2 233 ? 220.151 305.562 270.466 1.00 29.09  ? 231 LEU F CD2 1 
ATOM   16555 N  N   . ASN F 2 234 ? 218.450 300.410 271.075 1.00 32.24  ? 232 ASN F N   1 
ATOM   16556 C  CA  . ASN F 2 234 ? 217.507 299.341 270.761 1.00 31.32  ? 232 ASN F CA  1 
ATOM   16557 C  C   . ASN F 2 234 ? 217.383 298.470 272.002 1.00 30.77  ? 232 ASN F C   1 
ATOM   16558 O  O   . ASN F 2 234 ? 218.328 297.762 272.360 1.00 36.74  ? 232 ASN F O   1 
ATOM   16559 C  CB  . ASN F 2 234 ? 217.970 298.521 269.556 1.00 34.16  ? 232 ASN F CB  1 
ATOM   16560 C  CG  . ASN F 2 234 ? 216.922 297.535 269.083 1.00 32.88  ? 232 ASN F CG  1 
ATOM   16561 O  OD1 . ASN F 2 234 ? 215.928 297.292 269.767 1.00 36.09  ? 232 ASN F OD1 1 
ATOM   16562 N  ND2 . ASN F 2 234 ? 217.140 296.957 267.909 1.00 32.11  ? 232 ASN F ND2 1 
ATOM   16563 N  N   . ASN F 2 235 ? 216.226 298.521 272.657 1.00 30.31  ? 233 ASN F N   1 
ATOM   16564 C  CA  . ASN F 2 235 ? 216.027 297.854 273.935 1.00 26.58  ? 233 ASN F CA  1 
ATOM   16565 C  C   . ASN F 2 235 ? 215.432 296.459 273.793 1.00 26.95  ? 233 ASN F C   1 
ATOM   16566 O  O   . ASN F 2 235 ? 215.054 295.856 274.801 1.00 34.62  ? 233 ASN F O   1 
ATOM   16567 C  CB  . ASN F 2 235 ? 215.138 298.710 274.842 1.00 19.84  ? 233 ASN F CB  1 
ATOM   16568 C  CG  . ASN F 2 235 ? 215.661 300.125 275.001 1.00 23.67  ? 233 ASN F CG  1 
ATOM   16569 O  OD1 . ASN F 2 235 ? 214.908 301.090 274.894 1.00 26.32  ? 233 ASN F OD1 1 
ATOM   16570 N  ND2 . ASN F 2 235 ? 216.956 300.254 275.260 1.00 26.14  ? 233 ASN F ND2 1 
ATOM   16571 N  N   . THR F 2 236 ? 215.335 295.936 272.573 1.00 32.21  ? 234 THR F N   1 
ATOM   16572 C  CA  . THR F 2 236 ? 214.896 294.560 272.386 1.00 32.29  ? 234 THR F CA  1 
ATOM   16573 C  C   . THR F 2 236 ? 215.879 293.595 273.037 1.00 35.17  ? 234 THR F C   1 
ATOM   16574 O  O   . THR F 2 236 ? 217.094 293.710 272.856 1.00 40.60  ? 234 THR F O   1 
ATOM   16575 C  CB  . THR F 2 236 ? 214.761 294.245 270.895 1.00 30.55  ? 234 THR F CB  1 
ATOM   16576 O  OG1 . THR F 2 236 ? 213.962 295.249 270.262 1.00 38.27  ? 234 THR F OG1 1 
ATOM   16577 C  CG2 . THR F 2 236 ? 214.114 292.885 270.692 1.00 36.23  ? 234 THR F CG2 1 
ATOM   16578 N  N   . ARG F 2 237 ? 215.347 292.636 273.797 1.00 39.26  ? 235 ARG F N   1 
ATOM   16579 C  CA  . ARG F 2 237 ? 216.166 291.616 274.452 1.00 36.27  ? 235 ARG F CA  1 
ATOM   16580 C  C   . ARG F 2 237 ? 216.249 290.408 273.525 1.00 37.07  ? 235 ARG F C   1 
ATOM   16581 O  O   . ARG F 2 237 ? 215.586 289.386 273.710 1.00 44.04  ? 235 ARG F O   1 
ATOM   16582 C  CB  . ARG F 2 237 ? 215.587 291.250 275.813 1.00 34.61  ? 235 ARG F CB  1 
ATOM   16583 C  CG  . ARG F 2 237 ? 215.717 292.342 276.859 1.00 36.67  ? 235 ARG F CG  1 
ATOM   16584 C  CD  . ARG F 2 237 ? 214.664 292.196 277.942 1.00 48.29  ? 235 ARG F CD  1 
ATOM   16585 N  NE  . ARG F 2 237 ? 215.098 291.298 279.005 1.00 53.14  ? 235 ARG F NE  1 
ATOM   16586 C  CZ  . ARG F 2 237 ? 214.657 290.058 279.166 1.00 54.56  ? 235 ARG F CZ  1 
ATOM   16587 N  NH1 . ARG F 2 237 ? 213.763 289.531 278.346 1.00 54.55  ? 235 ARG F NH1 1 
ATOM   16588 N  NH2 . ARG F 2 237 ? 215.127 289.328 280.173 1.00 53.56  ? 235 ARG F NH2 1 
ATOM   16589 N  N   . ASN F 2 238 ? 217.093 290.538 272.503 1.00 39.53  ? 236 ASN F N   1 
ATOM   16590 C  CA  . ASN F 2 238 ? 217.193 289.541 271.447 1.00 48.49  ? 236 ASN F CA  1 
ATOM   16591 C  C   . ASN F 2 238 ? 218.449 288.684 271.533 1.00 50.89  ? 236 ASN F C   1 
ATOM   16592 O  O   . ASN F 2 238 ? 218.557 287.704 270.790 1.00 51.37  ? 236 ASN F O   1 
ATOM   16593 C  CB  . ASN F 2 238 ? 217.141 290.223 270.074 1.00 48.16  ? 236 ASN F CB  1 
ATOM   16594 C  CG  . ASN F 2 238 ? 218.166 291.331 269.935 1.00 49.30  ? 236 ASN F CG  1 
ATOM   16595 O  OD1 . ASN F 2 238 ? 219.097 291.436 270.734 1.00 49.33  ? 236 ASN F OD1 1 
ATOM   16596 N  ND2 . ASN F 2 238 ? 217.998 292.169 268.919 1.00 51.56  ? 236 ASN F ND2 1 
ATOM   16597 N  N   . SER F 2 239 ? 219.390 289.018 272.406 1.00 49.39  ? 237 SER F N   1 
ATOM   16598 C  CA  . SER F 2 239 ? 220.642 288.286 272.531 1.00 42.22  ? 237 SER F CA  1 
ATOM   16599 C  C   . SER F 2 239 ? 220.786 287.750 273.952 1.00 39.56  ? 237 SER F C   1 
ATOM   16600 O  O   . SER F 2 239 ? 219.931 287.964 274.812 1.00 39.78  ? 237 SER F O   1 
ATOM   16601 C  CB  . SER F 2 239 ? 221.831 289.175 272.156 1.00 42.61  ? 237 SER F CB  1 
ATOM   16602 O  OG  . SER F 2 239 ? 222.942 288.395 271.754 1.00 50.44  ? 237 SER F OG  1 
ATOM   16603 N  N   . THR F 2 240 ? 221.882 287.033 274.187 1.00 41.84  ? 238 THR F N   1 
ATOM   16604 C  CA  . THR F 2 240 ? 222.207 286.497 275.499 1.00 38.47  ? 238 THR F CA  1 
ATOM   16605 C  C   . THR F 2 240 ? 223.639 286.871 275.855 1.00 34.46  ? 238 THR F C   1 
ATOM   16606 O  O   . THR F 2 240 ? 224.426 287.280 274.999 1.00 38.36  ? 238 THR F O   1 
ATOM   16607 C  CB  . THR F 2 240 ? 222.032 284.972 275.553 1.00 39.29  ? 238 THR F CB  1 
ATOM   16608 O  OG1 . THR F 2 240 ? 223.077 284.339 274.806 1.00 37.53  ? 238 THR F OG1 1 
ATOM   16609 C  CG2 . THR F 2 240 ? 220.688 284.568 274.971 1.00 40.39  ? 238 THR F CG2 1 
ATOM   16610 N  N   . ILE F 2 241 ? 223.967 286.733 277.141 1.00 37.72  ? 239 ILE F N   1 
ATOM   16611 C  CA  . ILE F 2 241 ? 225.334 286.989 277.588 1.00 34.96  ? 239 ILE F CA  1 
ATOM   16612 C  C   . ILE F 2 241 ? 226.303 286.035 276.902 1.00 33.23  ? 239 ILE F C   1 
ATOM   16613 O  O   . ILE F 2 241 ? 227.434 286.408 276.562 1.00 37.15  ? 239 ILE F O   1 
ATOM   16614 C  CB  . ILE F 2 241 ? 225.424 286.885 279.122 1.00 34.73  ? 239 ILE F CB  1 
ATOM   16615 C  CG1 . ILE F 2 241 ? 224.263 287.634 279.777 1.00 37.92  ? 239 ILE F CG1 1 
ATOM   16616 C  CG2 . ILE F 2 241 ? 226.756 287.420 279.620 1.00 33.15  ? 239 ILE F CG2 1 
ATOM   16617 C  CD1 . ILE F 2 241 ? 224.519 289.109 279.970 1.00 36.23  ? 239 ILE F CD1 1 
ATOM   16618 N  N   . ASP F 2 242 ? 225.879 284.787 276.693 1.00 33.22  ? 240 ASP F N   1 
ATOM   16619 C  CA  . ASP F 2 242 ? 226.718 283.833 275.978 1.00 34.19  ? 240 ASP F CA  1 
ATOM   16620 C  C   . ASP F 2 242 ? 227.004 284.311 274.561 1.00 37.44  ? 240 ASP F C   1 
ATOM   16621 O  O   . ASP F 2 242 ? 228.133 284.191 274.075 1.00 42.21  ? 240 ASP F O   1 
ATOM   16622 C  CB  . ASP F 2 242 ? 226.053 282.458 275.963 1.00 36.49  ? 240 ASP F CB  1 
ATOM   16623 C  CG  . ASP F 2 242 ? 226.985 281.367 275.481 1.00 43.80  ? 240 ASP F CG  1 
ATOM   16624 O  OD1 . ASP F 2 242 ? 228.176 281.394 275.849 1.00 46.10  ? 240 ASP F OD1 1 
ATOM   16625 O  OD2 . ASP F 2 242 ? 226.524 280.480 274.734 1.00 51.46  ? 240 ASP F OD2 1 
ATOM   16626 N  N   . ASP F 2 243 ? 225.990 284.847 273.876 1.00 35.86  ? 241 ASP F N   1 
ATOM   16627 C  CA  . ASP F 2 243 ? 226.219 285.427 272.556 1.00 34.53  ? 241 ASP F CA  1 
ATOM   16628 C  C   . ASP F 2 243 ? 227.115 286.654 272.648 1.00 36.32  ? 241 ASP F C   1 
ATOM   16629 O  O   . ASP F 2 243 ? 227.924 286.913 271.750 1.00 35.31  ? 241 ASP F O   1 
ATOM   16630 C  CB  . ASP F 2 243 ? 224.888 285.790 271.898 1.00 36.40  ? 241 ASP F CB  1 
ATOM   16631 C  CG  . ASP F 2 243 ? 224.100 284.572 271.466 1.00 45.47  ? 241 ASP F CG  1 
ATOM   16632 O  OD1 . ASP F 2 243 ? 224.688 283.678 270.824 1.00 49.19  ? 241 ASP F OD1 1 
ATOM   16633 O  OD2 . ASP F 2 243 ? 222.888 284.512 271.763 1.00 46.43  ? 241 ASP F OD2 1 
ATOM   16634 N  N   . PHE F 2 244 ? 226.978 287.427 273.726 1.00 34.66  ? 242 PHE F N   1 
ATOM   16635 C  CA  . PHE F 2 244 ? 227.825 288.599 273.910 1.00 32.66  ? 242 PHE F CA  1 
ATOM   16636 C  C   . PHE F 2 244 ? 229.294 288.208 273.990 1.00 33.59  ? 242 PHE F C   1 
ATOM   16637 O  O   . PHE F 2 244 ? 230.150 288.853 273.373 1.00 37.05  ? 242 PHE F O   1 
ATOM   16638 C  CB  . PHE F 2 244 ? 227.398 289.352 275.171 1.00 34.65  ? 242 PHE F CB  1 
ATOM   16639 C  CG  . PHE F 2 244 ? 228.246 290.549 275.483 1.00 34.78  ? 242 PHE F CG  1 
ATOM   16640 C  CD1 . PHE F 2 244 ? 228.049 291.746 274.820 1.00 33.04  ? 242 PHE F CD1 1 
ATOM   16641 C  CD2 . PHE F 2 244 ? 229.238 290.477 276.446 1.00 31.97  ? 242 PHE F CD2 1 
ATOM   16642 C  CE1 . PHE F 2 244 ? 228.824 292.846 275.108 1.00 32.76  ? 242 PHE F CE1 1 
ATOM   16643 C  CE2 . PHE F 2 244 ? 230.017 291.575 276.737 1.00 31.88  ? 242 PHE F CE2 1 
ATOM   16644 C  CZ  . PHE F 2 244 ? 229.809 292.761 276.068 1.00 31.88  ? 242 PHE F CZ  1 
ATOM   16645 N  N   . PHE F 2 245 ? 229.608 287.154 274.745 1.00 33.28  ? 243 PHE F N   1 
ATOM   16646 C  CA  . PHE F 2 245 ? 230.997 286.722 274.861 1.00 28.51  ? 243 PHE F CA  1 
ATOM   16647 C  C   . PHE F 2 245 ? 231.480 285.998 273.608 1.00 33.11  ? 243 PHE F C   1 
ATOM   16648 O  O   . PHE F 2 245 ? 232.613 286.215 273.165 1.00 36.35  ? 243 PHE F O   1 
ATOM   16649 C  CB  . PHE F 2 245 ? 231.173 285.835 276.094 1.00 28.86  ? 243 PHE F CB  1 
ATOM   16650 C  CG  . PHE F 2 245 ? 231.326 286.605 277.372 1.00 29.10  ? 243 PHE F CG  1 
ATOM   16651 C  CD1 . PHE F 2 245 ? 232.385 287.479 277.544 1.00 33.01  ? 243 PHE F CD1 1 
ATOM   16652 C  CD2 . PHE F 2 245 ? 230.411 286.459 278.397 1.00 24.88  ? 243 PHE F CD2 1 
ATOM   16653 C  CE1 . PHE F 2 245 ? 232.529 288.191 278.716 1.00 27.48  ? 243 PHE F CE1 1 
ATOM   16654 C  CE2 . PHE F 2 245 ? 230.550 287.169 279.572 1.00 23.40  ? 243 PHE F CE2 1 
ATOM   16655 C  CZ  . PHE F 2 245 ? 231.610 288.035 279.732 1.00 24.63  ? 243 PHE F CZ  1 
ATOM   16656 N  N   . ARG F 2 246 ? 230.644 285.137 273.023 1.00 34.80  ? 244 ARG F N   1 
ATOM   16657 C  CA  . ARG F 2 246 ? 231.068 284.378 271.851 1.00 31.30  ? 244 ARG F CA  1 
ATOM   16658 C  C   . ARG F 2 246 ? 231.286 285.287 270.648 1.00 36.34  ? 244 ARG F C   1 
ATOM   16659 O  O   . ARG F 2 246 ? 232.222 285.081 269.868 1.00 38.27  ? 244 ARG F O   1 
ATOM   16660 C  CB  . ARG F 2 246 ? 230.043 283.294 271.526 1.00 30.41  ? 244 ARG F CB  1 
ATOM   16661 C  CG  . ARG F 2 246 ? 230.423 282.417 270.345 1.00 29.56  ? 244 ARG F CG  1 
ATOM   16662 C  CD  . ARG F 2 246 ? 231.415 281.341 270.750 1.00 29.89  ? 244 ARG F CD  1 
ATOM   16663 N  NE  . ARG F 2 246 ? 231.780 280.482 269.630 1.00 30.65  ? 244 ARG F NE  1 
ATOM   16664 C  CZ  . ARG F 2 246 ? 232.755 280.741 268.771 1.00 31.73  ? 244 ARG F CZ  1 
ATOM   16665 N  NH1 . ARG F 2 246 ? 233.491 281.836 268.871 1.00 32.89  ? 244 ARG F NH1 1 
ATOM   16666 N  NH2 . ARG F 2 246 ? 233.000 279.881 267.789 1.00 32.25  ? 244 ARG F NH2 1 
ATOM   16667 N  N   . LEU F 2 247 ? 230.429 286.294 270.475 1.00 36.61  ? 245 LEU F N   1 
ATOM   16668 C  CA  . LEU F 2 247 ? 230.603 287.240 269.381 1.00 35.17  ? 245 LEU F CA  1 
ATOM   16669 C  C   . LEU F 2 247 ? 231.731 288.226 269.638 1.00 36.63  ? 245 LEU F C   1 
ATOM   16670 O  O   . LEU F 2 247 ? 232.094 288.975 268.725 1.00 41.90  ? 245 LEU F O   1 
ATOM   16671 C  CB  . LEU F 2 247 ? 229.300 287.999 269.126 1.00 37.86  ? 245 LEU F CB  1 
ATOM   16672 C  CG  . LEU F 2 247 ? 228.160 287.201 268.493 1.00 39.39  ? 245 LEU F CG  1 
ATOM   16673 C  CD1 . LEU F 2 247 ? 226.941 288.082 268.289 1.00 34.13  ? 245 LEU F CD1 1 
ATOM   16674 C  CD2 . LEU F 2 247 ? 228.604 286.588 267.179 1.00 37.73  ? 245 LEU F CD2 1 
ATOM   16675 N  N   . ASN F 2 248 ? 232.285 288.247 270.849 1.00 34.13  ? 246 ASN F N   1 
ATOM   16676 C  CA  . ASN F 2 248 ? 233.382 289.146 271.199 1.00 32.60  ? 246 ASN F CA  1 
ATOM   16677 C  C   . ASN F 2 248 ? 232.963 290.607 271.044 1.00 36.33  ? 246 ASN F C   1 
ATOM   16678 O  O   . ASN F 2 248 ? 233.622 291.401 270.372 1.00 37.82  ? 246 ASN F O   1 
ATOM   16679 C  CB  . ASN F 2 248 ? 234.629 288.839 270.366 1.00 35.81  ? 246 ASN F CB  1 
ATOM   16680 C  CG  . ASN F 2 248 ? 235.255 287.506 270.726 1.00 45.29  ? 246 ASN F CG  1 
ATOM   16681 O  OD1 . ASN F 2 248 ? 235.232 286.562 269.938 1.00 45.34  ? 246 ASN F OD1 1 
ATOM   16682 N  ND2 . ASN F 2 248 ? 235.810 287.421 271.929 1.00 45.25  ? 246 ASN F ND2 1 
ATOM   16683 N  N   . LEU F 2 249 ? 231.847 290.958 271.680 1.00 34.19  ? 247 LEU F N   1 
ATOM   16684 C  CA  . LEU F 2 249 ? 231.336 292.320 271.638 1.00 31.94  ? 247 LEU F CA  1 
ATOM   16685 C  C   . LEU F 2 249 ? 231.870 293.190 272.765 1.00 38.17  ? 247 LEU F C   1 
ATOM   16686 O  O   . LEU F 2 249 ? 231.610 294.397 272.772 1.00 42.68  ? 247 LEU F O   1 
ATOM   16687 C  CB  . LEU F 2 249 ? 229.806 292.310 271.679 1.00 32.38  ? 247 LEU F CB  1 
ATOM   16688 C  CG  . LEU F 2 249 ? 229.135 291.539 270.541 1.00 35.80  ? 247 LEU F CG  1 
ATOM   16689 C  CD1 . LEU F 2 249 ? 227.633 291.449 270.754 1.00 36.81  ? 247 LEU F CD1 1 
ATOM   16690 C  CD2 . LEU F 2 249 ? 229.456 292.181 269.200 1.00 38.31  ? 247 LEU F CD2 1 
ATOM   16691 N  N   . TYR F 2 250 ? 232.602 292.610 273.711 1.00 38.48  ? 248 TYR F N   1 
ATOM   16692 C  CA  . TYR F 2 250 ? 233.217 293.379 274.779 1.00 34.59  ? 248 TYR F CA  1 
ATOM   16693 C  C   . TYR F 2 250 ? 234.511 294.018 274.293 1.00 39.32  ? 248 TYR F C   1 
ATOM   16694 O  O   . TYR F 2 250 ? 235.209 293.479 273.430 1.00 40.05  ? 248 TYR F O   1 
ATOM   16695 C  CB  . TYR F 2 250 ? 233.494 292.487 275.988 1.00 34.44  ? 248 TYR F CB  1 
ATOM   16696 C  CG  . TYR F 2 250 ? 234.362 291.295 275.669 1.00 36.69  ? 248 TYR F CG  1 
ATOM   16697 C  CD1 . TYR F 2 250 ? 233.814 290.136 275.140 1.00 36.35  ? 248 TYR F CD1 1 
ATOM   16698 C  CD2 . TYR F 2 250 ? 235.730 291.331 275.890 1.00 37.66  ? 248 TYR F CD2 1 
ATOM   16699 C  CE1 . TYR F 2 250 ? 234.603 289.048 274.843 1.00 37.22  ? 248 TYR F CE1 1 
ATOM   16700 C  CE2 . TYR F 2 250 ? 236.526 290.249 275.598 1.00 34.39  ? 248 TYR F CE2 1 
ATOM   16701 C  CZ  . TYR F 2 250 ? 235.958 289.110 275.074 1.00 37.07  ? 248 TYR F CZ  1 
ATOM   16702 O  OH  . TYR F 2 250 ? 236.749 288.025 274.780 1.00 38.46  ? 248 TYR F OH  1 
ATOM   16703 N  N   . LYS F 2 251 ? 234.825 295.183 274.855 1.00 42.26  ? 249 LYS F N   1 
ATOM   16704 C  CA  . LYS F 2 251 ? 236.031 295.928 274.508 1.00 37.50  ? 249 LYS F CA  1 
ATOM   16705 C  C   . LYS F 2 251 ? 236.847 296.154 275.772 1.00 39.85  ? 249 LYS F C   1 
ATOM   16706 O  O   . LYS F 2 251 ? 236.447 296.931 276.646 1.00 44.17  ? 249 LYS F O   1 
ATOM   16707 C  CB  . LYS F 2 251 ? 235.686 297.257 273.838 1.00 40.73  ? 249 LYS F CB  1 
ATOM   16708 C  CG  . LYS F 2 251 ? 234.646 297.152 272.741 1.00 51.32  ? 249 LYS F CG  1 
ATOM   16709 C  CD  . LYS F 2 251 ? 235.301 297.100 271.372 1.00 51.87  ? 249 LYS F CD  1 
ATOM   16710 C  CE  . LYS F 2 251 ? 234.307 297.437 270.275 1.00 60.68  ? 249 LYS F CE  1 
ATOM   16711 N  NZ  . LYS F 2 251 ? 233.363 298.508 270.696 1.00 64.33  ? 249 LYS F NZ  1 
ATOM   16712 N  N   . GLY F 2 252 ? 237.992 295.480 275.865 1.00 41.22  ? 250 GLY F N   1 
ATOM   16713 C  CA  . GLY F 2 252 ? 238.897 295.676 276.972 1.00 38.91  ? 250 GLY F CA  1 
ATOM   16714 C  C   . GLY F 2 252 ? 240.327 295.790 276.481 1.00 40.49  ? 250 GLY F C   1 
ATOM   16715 O  O   . GLY F 2 252 ? 240.662 295.383 275.370 1.00 43.98  ? 250 GLY F O   1 
ATOM   16716 N  N   . ASP F 2 253 ? 241.169 296.358 277.335 1.00 39.58  ? 251 ASP F N   1 
ATOM   16717 C  CA  . ASP F 2 253 ? 242.586 296.492 277.042 1.00 41.22  ? 251 ASP F CA  1 
ATOM   16718 C  C   . ASP F 2 253 ? 243.380 295.411 277.765 1.00 39.13  ? 251 ASP F C   1 
ATOM   16719 O  O   . ASP F 2 253 ? 243.004 294.953 278.847 1.00 37.71  ? 251 ASP F O   1 
ATOM   16720 C  CB  . ASP F 2 253 ? 243.096 297.889 277.413 1.00 43.49  ? 251 ASP F CB  1 
ATOM   16721 C  CG  . ASP F 2 253 ? 242.934 298.211 278.887 1.00 54.79  ? 251 ASP F CG  1 
ATOM   16722 O  OD1 . ASP F 2 253 ? 242.883 297.283 279.719 1.00 51.24  ? 251 ASP F OD1 1 
ATOM   16723 O  OD2 . ASP F 2 253 ? 242.857 299.413 279.215 1.00 64.17  ? 251 ASP F OD2 1 
ATOM   16724 N  N   . ILE F 2 254 ? 244.481 294.996 277.142 1.00 35.95  ? 252 ILE F N   1 
ATOM   16725 C  CA  . ILE F 2 254 ? 245.252 293.866 277.642 1.00 33.46  ? 252 ILE F CA  1 
ATOM   16726 C  C   . ILE F 2 254 ? 246.020 294.277 278.890 1.00 33.57  ? 252 ILE F C   1 
ATOM   16727 O  O   . ILE F 2 254 ? 246.679 295.324 278.921 1.00 39.46  ? 252 ILE F O   1 
ATOM   16728 C  CB  . ILE F 2 254 ? 246.195 293.338 276.552 1.00 33.68  ? 252 ILE F CB  1 
ATOM   16729 C  CG1 . ILE F 2 254 ? 245.384 292.808 275.370 1.00 33.15  ? 252 ILE F CG1 1 
ATOM   16730 C  CG2 . ILE F 2 254 ? 247.099 292.251 277.107 1.00 31.67  ? 252 ILE F CG2 1 
ATOM   16731 C  CD1 . ILE F 2 254 ? 246.017 293.065 274.028 1.00 33.72  ? 252 ILE F CD1 1 
ATOM   16732 N  N   . VAL F 2 255 ? 245.932 293.451 279.929 1.00 29.82  ? 253 VAL F N   1 
ATOM   16733 C  CA  . VAL F 2 255 ? 246.669 293.677 281.167 1.00 33.17  ? 253 VAL F CA  1 
ATOM   16734 C  C   . VAL F 2 255 ? 247.685 292.585 281.454 1.00 33.04  ? 253 VAL F C   1 
ATOM   16735 O  O   . VAL F 2 255 ? 248.506 292.751 282.368 1.00 39.04  ? 253 VAL F O   1 
ATOM   16736 C  CB  . VAL F 2 255 ? 245.716 293.834 282.372 1.00 31.97  ? 253 VAL F CB  1 
ATOM   16737 C  CG1 . VAL F 2 255 ? 244.728 294.959 282.120 1.00 31.82  ? 253 VAL F CG1 1 
ATOM   16738 C  CG2 . VAL F 2 255 ? 244.991 292.528 282.651 1.00 26.55  ? 253 VAL F CG2 1 
ATOM   16739 N  N   . LYS F 2 256 ? 247.661 291.478 280.717 1.00 30.79  ? 254 LYS F N   1 
ATOM   16740 C  CA  . LYS F 2 256 ? 248.594 290.387 280.947 1.00 29.54  ? 254 LYS F CA  1 
ATOM   16741 C  C   . LYS F 2 256 ? 248.638 289.500 279.713 1.00 32.54  ? 254 LYS F C   1 
ATOM   16742 O  O   . LYS F 2 256 ? 247.641 289.346 279.004 1.00 32.53  ? 254 LYS F O   1 
ATOM   16743 C  CB  . LYS F 2 256 ? 248.201 289.566 282.178 1.00 32.89  ? 254 LYS F CB  1 
ATOM   16744 C  CG  . LYS F 2 256 ? 249.238 288.545 282.601 1.00 30.65  ? 254 LYS F CG  1 
ATOM   16745 C  CD  . LYS F 2 256 ? 248.882 287.939 283.943 1.00 36.69  ? 254 LYS F CD  1 
ATOM   16746 C  CE  . LYS F 2 256 ? 249.619 286.632 284.174 1.00 38.87  ? 254 LYS F CE  1 
ATOM   16747 N  NZ  . LYS F 2 256 ? 250.979 286.651 283.576 1.00 43.42  ? 254 LYS F NZ  1 
ATOM   16748 N  N   . THR F 2 257 ? 249.806 288.924 279.468 1.00 37.20  ? 255 THR F N   1 
ATOM   16749 C  CA  . THR F 2 257 ? 250.001 287.969 278.391 1.00 30.76  ? 255 THR F CA  1 
ATOM   16750 C  C   . THR F 2 257 ? 250.769 286.775 278.932 1.00 32.47  ? 255 THR F C   1 
ATOM   16751 O  O   . THR F 2 257 ? 251.597 286.911 279.836 1.00 40.04  ? 255 THR F O   1 
ATOM   16752 C  CB  . THR F 2 257 ? 250.755 288.603 277.210 1.00 35.89  ? 255 THR F CB  1 
ATOM   16753 O  OG1 . THR F 2 257 ? 249.838 289.341 276.393 1.00 33.26  ? 255 THR F OG1 1 
ATOM   16754 C  CG2 . THR F 2 257 ? 251.443 287.543 276.367 1.00 40.58  ? 255 THR F CG2 1 
ATOM   16755 N  N   . GLU F 2 258 ? 250.484 285.598 278.382 1.00 33.11  ? 256 GLU F N   1 
ATOM   16756 C  CA  . GLU F 2 258 ? 251.227 284.412 278.782 1.00 36.65  ? 256 GLU F CA  1 
ATOM   16757 C  C   . GLU F 2 258 ? 252.635 284.459 278.204 1.00 37.89  ? 256 GLU F C   1 
ATOM   16758 O  O   . GLU F 2 258 ? 252.866 284.022 277.073 1.00 45.23  ? 256 GLU F O   1 
ATOM   16759 C  CB  . GLU F 2 258 ? 250.506 283.140 278.338 1.00 32.60  ? 256 GLU F CB  1 
ATOM   16760 C  CG  . GLU F 2 258 ? 250.780 281.949 279.235 1.00 39.97  ? 256 GLU F CG  1 
ATOM   16761 C  CD  . GLU F 2 258 ? 250.357 280.638 278.614 1.00 51.57  ? 256 GLU F CD  1 
ATOM   16762 O  OE1 . GLU F 2 258 ? 251.097 280.124 277.751 1.00 56.82  ? 256 GLU F OE1 1 
ATOM   16763 O  OE2 . GLU F 2 258 ? 249.290 280.115 278.995 1.00 55.97  ? 256 GLU F OE2 1 
ATOM   16764 N  N   . ASN F 2 259 ? 253.579 284.991 278.973 1.00 39.08  ? 257 ASN F N   1 
ATOM   16765 C  CA  . ASN F 2 259 ? 254.969 285.094 278.561 1.00 38.60  ? 257 ASN F CA  1 
ATOM   16766 C  C   . ASN F 2 259 ? 255.824 284.184 279.432 1.00 40.18  ? 257 ASN F C   1 
ATOM   16767 O  O   . ASN F 2 259 ? 255.366 283.629 280.433 1.00 41.94  ? 257 ASN F O   1 
ATOM   16768 C  CB  . ASN F 2 259 ? 255.466 286.543 278.639 1.00 35.92  ? 257 ASN F CB  1 
ATOM   16769 C  CG  . ASN F 2 259 ? 255.118 287.209 279.953 1.00 40.19  ? 257 ASN F CG  1 
ATOM   16770 O  OD1 . ASN F 2 259 ? 255.772 286.982 280.968 1.00 44.39  ? 257 ASN F OD1 1 
ATOM   16771 N  ND2 . ASN F 2 259 ? 254.087 288.043 279.938 1.00 41.06  ? 257 ASN F ND2 1 
ATOM   16772 N  N   . LEU F 2 260 ? 257.090 284.038 279.037 1.00 42.10  ? 258 LEU F N   1 
ATOM   16773 C  CA  . LEU F 2 260 ? 257.974 283.091 279.706 1.00 42.50  ? 258 LEU F CA  1 
ATOM   16774 C  C   . LEU F 2 260 ? 258.381 283.550 281.100 1.00 43.00  ? 258 LEU F C   1 
ATOM   16775 O  O   . LEU F 2 260 ? 258.771 282.714 281.922 1.00 42.84  ? 258 LEU F O   1 
ATOM   16776 C  CB  . LEU F 2 260 ? 259.216 282.845 278.850 1.00 37.23  ? 258 LEU F CB  1 
ATOM   16777 C  CG  . LEU F 2 260 ? 258.968 282.075 277.551 1.00 34.99  ? 258 LEU F CG  1 
ATOM   16778 C  CD1 . LEU F 2 260 ? 260.151 282.201 276.607 1.00 36.01  ? 258 LEU F CD1 1 
ATOM   16779 C  CD2 . LEU F 2 260 ? 258.661 280.616 277.841 1.00 37.79  ? 258 LEU F CD2 1 
ATOM   16780 N  N   . HIS F 2 261 ? 258.302 284.845 281.386 1.00 43.84  ? 259 HIS F N   1 
ATOM   16781 C  CA  . HIS F 2 261 ? 258.666 285.373 282.694 1.00 44.21  ? 259 HIS F CA  1 
ATOM   16782 C  C   . HIS F 2 261 ? 257.482 285.497 283.643 1.00 47.90  ? 259 HIS F C   1 
ATOM   16783 O  O   . HIS F 2 261 ? 257.672 285.902 284.793 1.00 53.22  ? 259 HIS F O   1 
ATOM   16784 C  CB  . HIS F 2 261 ? 259.342 286.738 282.541 1.00 45.74  ? 259 HIS F CB  1 
ATOM   16785 C  CG  . HIS F 2 261 ? 260.644 286.686 281.807 1.00 53.78  ? 259 HIS F CG  1 
ATOM   16786 N  ND1 . HIS F 2 261 ? 260.808 287.212 280.544 1.00 56.82  ? 259 HIS F ND1 1 
ATOM   16787 C  CD2 . HIS F 2 261 ? 261.845 286.167 282.157 1.00 50.42  ? 259 HIS F CD2 1 
ATOM   16788 C  CE1 . HIS F 2 261 ? 262.054 287.022 280.149 1.00 59.51  ? 259 HIS F CE1 1 
ATOM   16789 N  NE2 . HIS F 2 261 ? 262.704 286.390 281.109 1.00 56.60  ? 259 HIS F NE2 1 
ATOM   16790 N  N   . ASN F 2 262 ? 256.273 285.157 283.197 1.00 43.95  ? 260 ASN F N   1 
ATOM   16791 C  CA  . ASN F 2 262 ? 255.069 285.327 284.009 1.00 43.67  ? 260 ASN F CA  1 
ATOM   16792 C  C   . ASN F 2 262 ? 254.905 286.782 284.444 1.00 46.43  ? 260 ASN F C   1 
ATOM   16793 O  O   . ASN F 2 262 ? 254.469 287.074 285.559 1.00 44.40  ? 260 ASN F O   1 
ATOM   16794 C  CB  . ASN F 2 262 ? 255.083 284.397 285.223 1.00 44.19  ? 260 ASN F CB  1 
ATOM   16795 C  CG  . ASN F 2 262 ? 253.693 284.097 285.741 1.00 47.99  ? 260 ASN F CG  1 
ATOM   16796 O  OD1 . ASN F 2 262 ? 252.739 283.999 284.971 1.00 51.45  ? 260 ASN F OD1 1 
ATOM   16797 N  ND2 . ASN F 2 262 ? 253.569 283.955 287.054 1.00 50.67  ? 260 ASN F ND2 1 
ATOM   16798 N  N   . ARG F 2 263 ? 255.260 287.701 283.553 1.00 49.04  ? 261 ARG F N   1 
ATOM   16799 C  CA  . ARG F 2 263 ? 255.169 289.127 283.825 1.00 49.44  ? 261 ARG F CA  1 
ATOM   16800 C  C   . ARG F 2 263 ? 253.810 289.668 283.403 1.00 50.82  ? 261 ARG F C   1 
ATOM   16801 O  O   . ARG F 2 263 ? 253.260 289.268 282.373 1.00 48.98  ? 261 ARG F O   1 
ATOM   16802 C  CB  . ARG F 2 263 ? 256.273 289.886 283.089 1.00 50.08  ? 261 ARG F CB  1 
ATOM   16803 C  CG  . ARG F 2 263 ? 257.490 290.206 283.933 1.00 57.33  ? 261 ARG F CG  1 
ATOM   16804 C  CD  . ARG F 2 263 ? 258.311 291.304 283.282 1.00 66.61  ? 261 ARG F CD  1 
ATOM   16805 N  NE  . ARG F 2 263 ? 258.181 291.280 281.830 1.00 68.38  ? 261 ARG F NE  1 
ATOM   16806 C  CZ  . ARG F 2 263 ? 258.585 292.252 281.024 1.00 67.37  ? 261 ARG F CZ  1 
ATOM   16807 N  NH1 . ARG F 2 263 ? 259.156 293.348 281.495 1.00 64.92  ? 261 ARG F NH1 1 
ATOM   16808 N  NH2 . ARG F 2 263 ? 258.412 292.120 279.712 1.00 66.39  ? 261 ARG F NH2 1 
ATOM   16809 N  N   . ALA F 2 264 ? 253.274 290.575 284.208 1.00 51.19  ? 262 ALA F N   1 
ATOM   16810 C  CA  . ALA F 2 264 ? 252.086 291.333 283.853 1.00 45.85  ? 262 ALA F CA  1 
ATOM   16811 C  C   . ALA F 2 264 ? 252.490 292.682 283.271 1.00 49.94  ? 262 ALA F C   1 
ATOM   16812 O  O   . ALA F 2 264 ? 253.626 293.135 283.422 1.00 55.86  ? 262 ALA F O   1 
ATOM   16813 C  CB  . ALA F 2 264 ? 251.177 291.530 285.068 1.00 42.24  ? 262 ALA F CB  1 
ATOM   16814 N  N   . LEU F 2 265 ? 251.536 293.326 282.598 1.00 46.81  ? 263 LEU F N   1 
ATOM   16815 C  CA  . LEU F 2 265 ? 251.823 294.618 281.984 1.00 48.13  ? 263 LEU F CA  1 
ATOM   16816 C  C   . LEU F 2 265 ? 252.192 295.659 283.033 1.00 52.45  ? 263 LEU F C   1 
ATOM   16817 O  O   . LEU F 2 265 ? 253.058 296.508 282.797 1.00 52.49  ? 263 LEU F O   1 
ATOM   16818 C  CB  . LEU F 2 265 ? 250.624 295.088 281.162 1.00 44.64  ? 263 LEU F CB  1 
ATOM   16819 C  CG  . LEU F 2 265 ? 250.771 294.966 279.646 1.00 42.86  ? 263 LEU F CG  1 
ATOM   16820 C  CD1 . LEU F 2 265 ? 250.662 293.514 279.212 1.00 39.38  ? 263 LEU F CD1 1 
ATOM   16821 C  CD2 . LEU F 2 265 ? 249.734 295.821 278.940 1.00 43.76  ? 263 LEU F CD2 1 
ATOM   16822 N  N   . ALA F 2 266 ? 251.542 295.612 284.198 1.00 52.95  ? 264 ALA F N   1 
ATOM   16823 C  CA  . ALA F 2 266 ? 251.794 296.620 285.221 1.00 54.16  ? 264 ALA F CA  1 
ATOM   16824 C  C   . ALA F 2 266 ? 253.230 296.575 285.726 1.00 58.61  ? 264 ALA F C   1 
ATOM   16825 O  O   . ALA F 2 266 ? 253.775 297.608 286.130 1.00 65.25  ? 264 ALA F O   1 
ATOM   16826 C  CB  . ALA F 2 266 ? 250.820 296.441 286.385 1.00 48.79  ? 264 ALA F CB  1 
ATOM   16827 N  N   . GLU F 2 267 ? 253.859 295.399 285.714 1.00 58.57  ? 265 GLU F N   1 
ATOM   16828 C  CA  . GLU F 2 267 ? 255.199 295.273 286.274 1.00 56.20  ? 265 GLU F CA  1 
ATOM   16829 C  C   . GLU F 2 267 ? 256.241 296.056 285.488 1.00 58.65  ? 265 GLU F C   1 
ATOM   16830 O  O   . GLU F 2 267 ? 257.327 296.317 286.016 1.00 63.75  ? 265 GLU F O   1 
ATOM   16831 C  CB  . GLU F 2 267 ? 255.605 293.801 286.349 1.00 58.10  ? 265 GLU F CB  1 
ATOM   16832 C  CG  . GLU F 2 267 ? 254.552 292.899 286.962 1.00 59.04  ? 265 GLU F CG  1 
ATOM   16833 C  CD  . GLU F 2 267 ? 255.052 291.486 287.182 1.00 61.95  ? 265 GLU F CD  1 
ATOM   16834 O  OE1 . GLU F 2 267 ? 256.284 291.286 287.194 1.00 67.42  ? 265 GLU F OE1 1 
ATOM   16835 O  OE2 . GLU F 2 267 ? 254.213 290.576 287.343 1.00 57.31  ? 265 GLU F OE2 1 
ATOM   16836 N  N   . TYR F 2 268 ? 255.943 296.439 284.243 1.00 60.08  ? 266 TYR F N   1 
ATOM   16837 C  CA  . TYR F 2 268 ? 256.892 297.190 283.429 1.00 59.76  ? 266 TYR F CA  1 
ATOM   16838 C  C   . TYR F 2 268 ? 256.231 298.349 282.690 1.00 63.38  ? 266 TYR F C   1 
ATOM   16839 O  O   . TYR F 2 268 ? 256.788 298.846 281.706 1.00 64.09  ? 266 TYR F O   1 
ATOM   16840 C  CB  . TYR F 2 268 ? 257.610 296.269 282.439 1.00 56.14  ? 266 TYR F CB  1 
ATOM   16841 C  CG  . TYR F 2 268 ? 256.699 295.536 281.484 1.00 59.25  ? 266 TYR F CG  1 
ATOM   16842 C  CD1 . TYR F 2 268 ? 256.101 294.338 281.848 1.00 58.93  ? 266 TYR F CD1 1 
ATOM   16843 C  CD2 . TYR F 2 268 ? 256.449 296.033 280.214 1.00 60.10  ? 266 TYR F CD2 1 
ATOM   16844 C  CE1 . TYR F 2 268 ? 255.274 293.662 280.976 1.00 55.80  ? 266 TYR F CE1 1 
ATOM   16845 C  CE2 . TYR F 2 268 ? 255.624 295.365 279.337 1.00 55.00  ? 266 TYR F CE2 1 
ATOM   16846 C  CZ  . TYR F 2 268 ? 255.039 294.180 279.722 1.00 54.12  ? 266 TYR F CZ  1 
ATOM   16847 O  OH  . TYR F 2 268 ? 254.216 293.513 278.847 1.00 51.77  ? 266 TYR F OH  1 
ATOM   16848 N  N   . CYS F 2 269 ? 255.060 298.789 283.141 1.00 66.70  ? 267 CYS F N   1 
ATOM   16849 C  CA  . CYS F 2 269 ? 254.396 299.976 282.603 1.00 70.51  ? 267 CYS F CA  1 
ATOM   16850 C  C   . CYS F 2 269 ? 253.978 300.853 283.775 1.00 73.08  ? 267 CYS F C   1 
ATOM   16851 O  O   . CYS F 2 269 ? 252.965 300.569 284.437 1.00 71.01  ? 267 CYS F O   1 
ATOM   16852 C  CB  . CYS F 2 269 ? 253.195 299.604 281.741 1.00 66.88  ? 267 CYS F CB  1 
ATOM   16853 S  SG  . CYS F 2 269 ? 253.539 298.356 280.483 1.00 69.61  ? 267 CYS F SG  1 
ATOM   16854 N  N   . PRO F 2 270 ? 254.726 301.920 284.066 1.00 76.59  ? 268 PRO F N   1 
ATOM   16855 C  CA  . PRO F 2 270 ? 254.433 302.693 285.285 1.00 75.84  ? 268 PRO F CA  1 
ATOM   16856 C  C   . PRO F 2 270 ? 253.134 303.475 285.219 1.00 78.17  ? 268 PRO F C   1 
ATOM   16857 O  O   . PRO F 2 270 ? 252.369 303.471 286.191 1.00 76.52  ? 268 PRO F O   1 
ATOM   16858 C  CB  . PRO F 2 270 ? 255.650 303.621 285.408 1.00 72.79  ? 268 PRO F CB  1 
ATOM   16859 C  CG  . PRO F 2 270 ? 256.175 303.741 284.018 1.00 76.81  ? 268 PRO F CG  1 
ATOM   16860 C  CD  . PRO F 2 270 ? 255.914 302.423 283.355 1.00 73.65  ? 268 PRO F CD  1 
ATOM   16861 N  N   . THR F 2 271 ? 252.858 304.145 284.108 1.00 79.88  ? 269 THR F N   1 
ATOM   16862 C  CA  . THR F 2 271 ? 251.727 305.052 284.006 1.00 77.52  ? 269 THR F CA  1 
ATOM   16863 C  C   . THR F 2 271 ? 250.613 304.462 283.150 1.00 75.21  ? 269 THR F C   1 
ATOM   16864 O  O   . THR F 2 271 ? 250.851 303.590 282.308 1.00 74.82  ? 269 THR F O   1 
ATOM   16865 C  CB  . THR F 2 271 ? 252.167 306.397 283.412 1.00 76.54  ? 269 THR F CB  1 
ATOM   16866 O  OG1 . THR F 2 271 ? 252.103 306.336 281.983 1.00 75.94  ? 269 THR F OG1 1 
ATOM   16867 C  CG2 . THR F 2 271 ? 253.591 306.721 283.835 1.00 74.22  ? 269 THR F CG2 1 
ATOM   16868 N  N   . PRO F 2 272 ? 249.372 304.915 283.348 1.00 71.81  ? 270 PRO F N   1 
ATOM   16869 C  CA  . PRO F 2 272 ? 248.262 304.388 282.537 1.00 72.21  ? 270 PRO F CA  1 
ATOM   16870 C  C   . PRO F 2 272 ? 248.452 304.597 281.046 1.00 68.48  ? 270 PRO F C   1 
ATOM   16871 O  O   . PRO F 2 272 ? 248.038 303.744 280.250 1.00 68.85  ? 270 PRO F O   1 
ATOM   16872 C  CB  . PRO F 2 272 ? 247.047 305.162 283.066 1.00 72.75  ? 270 PRO F CB  1 
ATOM   16873 C  CG  . PRO F 2 272 ? 247.442 305.607 284.437 1.00 73.68  ? 270 PRO F CG  1 
ATOM   16874 C  CD  . PRO F 2 272 ? 248.914 305.875 284.366 1.00 72.43  ? 270 PRO F CD  1 
ATOM   16875 N  N   . ASP F 2 273 ? 249.063 305.712 280.639 1.00 66.25  ? 271 ASP F N   1 
ATOM   16876 C  CA  . ASP F 2 273 ? 249.329 305.930 279.222 1.00 68.30  ? 271 ASP F CA  1 
ATOM   16877 C  C   . ASP F 2 273 ? 250.240 304.843 278.665 1.00 66.80  ? 271 ASP F C   1 
ATOM   16878 O  O   . ASP F 2 273 ? 250.019 304.339 277.557 1.00 65.61  ? 271 ASP F O   1 
ATOM   16879 C  CB  . ASP F 2 273 ? 249.946 307.313 279.015 1.00 72.34  ? 271 ASP F CB  1 
ATOM   16880 C  CG  . ASP F 2 273 ? 250.242 307.608 277.560 1.00 78.11  ? 271 ASP F CG  1 
ATOM   16881 O  OD1 . ASP F 2 273 ? 249.288 307.683 276.757 1.00 77.40  ? 271 ASP F OD1 1 
ATOM   16882 O  OD2 . ASP F 2 273 ? 251.433 307.766 277.219 1.00 77.09  ? 271 ASP F OD2 1 
ATOM   16883 N  N   . SER F 2 274 ? 251.268 304.464 279.425 1.00 64.89  ? 272 SER F N   1 
ATOM   16884 C  CA  . SER F 2 274 ? 252.145 303.387 278.985 1.00 65.94  ? 272 SER F CA  1 
ATOM   16885 C  C   . SER F 2 274 ? 251.404 302.057 278.934 1.00 64.87  ? 272 SER F C   1 
ATOM   16886 O  O   . SER F 2 274 ? 251.653 301.236 278.045 1.00 64.51  ? 272 SER F O   1 
ATOM   16887 C  CB  . SER F 2 274 ? 253.364 303.295 279.900 1.00 72.12  ? 272 SER F CB  1 
ATOM   16888 O  OG  . SER F 2 274 ? 254.394 304.152 279.442 1.00 76.59  ? 272 SER F OG  1 
ATOM   16889 N  N   . MET F 2 275 ? 250.495 301.822 279.883 1.00 62.89  ? 273 MET F N   1 
ATOM   16890 C  CA  . MET F 2 275 ? 249.691 300.605 279.839 1.00 57.51  ? 273 MET F CA  1 
ATOM   16891 C  C   . MET F 2 275 ? 248.855 300.552 278.566 1.00 56.72  ? 273 MET F C   1 
ATOM   16892 O  O   . MET F 2 275 ? 248.781 299.509 277.903 1.00 57.50  ? 273 MET F O   1 
ATOM   16893 C  CB  . MET F 2 275 ? 248.794 300.524 281.073 1.00 54.46  ? 273 MET F CB  1 
ATOM   16894 C  CG  . MET F 2 275 ? 249.548 300.375 282.381 1.00 58.62  ? 273 MET F CG  1 
ATOM   16895 S  SD  . MET F 2 275 ? 249.853 298.658 282.831 1.00 68.38  ? 273 MET F SD  1 
ATOM   16896 C  CE  . MET F 2 275 ? 248.181 298.067 283.073 1.00 46.05  ? 273 MET F CE  1 
ATOM   16897 N  N   . LYS F 2 276 ? 248.225 301.672 278.207 1.00 53.75  ? 274 LYS F N   1 
ATOM   16898 C  CA  . LYS F 2 276 ? 247.452 301.723 276.970 1.00 51.43  ? 274 LYS F CA  1 
ATOM   16899 C  C   . LYS F 2 276 ? 248.343 301.492 275.757 1.00 52.63  ? 274 LYS F C   1 
ATOM   16900 O  O   . LYS F 2 276 ? 247.958 300.785 274.818 1.00 53.62  ? 274 LYS F O   1 
ATOM   16901 C  CB  . LYS F 2 276 ? 246.732 303.066 276.857 1.00 54.96  ? 274 LYS F CB  1 
ATOM   16902 C  CG  . LYS F 2 276 ? 245.393 303.121 277.571 1.00 60.45  ? 274 LYS F CG  1 
ATOM   16903 C  CD  . LYS F 2 276 ? 245.009 304.555 277.893 1.00 70.54  ? 274 LYS F CD  1 
ATOM   16904 C  CE  . LYS F 2 276 ? 244.166 304.639 279.156 1.00 72.52  ? 274 LYS F CE  1 
ATOM   16905 N  NZ  . LYS F 2 276 ? 242.813 304.047 278.965 1.00 73.91  ? 274 LYS F NZ  1 
ATOM   16906 N  N   . MET F 2 277 ? 249.539 302.085 275.756 1.00 56.33  ? 275 MET F N   1 
ATOM   16907 C  CA  . MET F 2 277 ? 250.455 301.894 274.636 1.00 55.21  ? 275 MET F CA  1 
ATOM   16908 C  C   . MET F 2 277 ? 250.852 300.429 274.488 1.00 51.78  ? 275 MET F C   1 
ATOM   16909 O  O   . MET F 2 277 ? 250.885 299.894 273.373 1.00 52.58  ? 275 MET F O   1 
ATOM   16910 C  CB  . MET F 2 277 ? 251.695 302.768 274.823 1.00 60.22  ? 275 MET F CB  1 
ATOM   16911 C  CG  . MET F 2 277 ? 251.409 304.259 274.816 1.00 67.04  ? 275 MET F CG  1 
ATOM   16912 S  SD  . MET F 2 277 ? 250.162 304.725 273.601 1.00 86.42  ? 275 MET F SD  1 
ATOM   16913 C  CE  . MET F 2 277 ? 251.135 304.708 272.098 1.00 68.88  ? 275 MET F CE  1 
ATOM   16914 N  N   . GLU F 2 278 ? 251.157 299.765 275.604 1.00 50.61  ? 276 GLU F N   1 
ATOM   16915 C  CA  . GLU F 2 278 ? 251.544 298.358 275.552 1.00 49.27  ? 276 GLU F CA  1 
ATOM   16916 C  C   . GLU F 2 278 ? 250.383 297.481 275.097 1.00 50.47  ? 276 GLU F C   1 
ATOM   16917 O  O   . GLU F 2 278 ? 250.576 296.534 274.320 1.00 53.00  ? 276 GLU F O   1 
ATOM   16918 C  CB  . GLU F 2 278 ? 252.059 297.911 276.919 1.00 51.45  ? 276 GLU F CB  1 
ATOM   16919 C  CG  . GLU F 2 278 ? 252.654 296.514 276.943 1.00 51.32  ? 276 GLU F CG  1 
ATOM   16920 C  CD  . GLU F 2 278 ? 253.770 296.326 275.933 1.00 55.74  ? 276 GLU F CD  1 
ATOM   16921 O  OE1 . GLU F 2 278 ? 254.107 297.291 275.216 1.00 54.07  ? 276 GLU F OE1 1 
ATOM   16922 O  OE2 . GLU F 2 278 ? 254.316 295.207 275.861 1.00 54.38  ? 276 GLU F OE2 1 
ATOM   16923 N  N   . SER F 2 279 ? 249.171 297.775 275.572 1.00 46.18  ? 277 SER F N   1 
ATOM   16924 C  CA  . SER F 2 279 ? 248.003 297.035 275.108 1.00 41.91  ? 277 SER F CA  1 
ATOM   16925 C  C   . SER F 2 279 ? 247.808 297.207 273.607 1.00 43.97  ? 277 SER F C   1 
ATOM   16926 O  O   . SER F 2 279 ? 247.507 296.240 272.895 1.00 45.63  ? 277 SER F O   1 
ATOM   16927 C  CB  . SER F 2 279 ? 246.760 297.487 275.872 1.00 39.93  ? 277 SER F CB  1 
ATOM   16928 O  OG  . SER F 2 279 ? 245.577 297.077 275.210 1.00 43.30  ? 277 SER F OG  1 
ATOM   16929 N  N   . LYS F 2 280 ? 247.977 298.432 273.106 1.00 45.36  ? 278 LYS F N   1 
ATOM   16930 C  CA  . LYS F 2 280 ? 247.842 298.667 271.673 1.00 44.80  ? 278 LYS F CA  1 
ATOM   16931 C  C   . LYS F 2 280 ? 248.907 297.910 270.891 1.00 45.84  ? 278 LYS F C   1 
ATOM   16932 O  O   . LYS F 2 280 ? 248.631 297.366 269.816 1.00 43.92  ? 278 LYS F O   1 
ATOM   16933 C  CB  . LYS F 2 280 ? 247.915 300.165 271.379 1.00 47.64  ? 278 LYS F CB  1 
ATOM   16934 C  CG  . LYS F 2 280 ? 247.028 300.615 270.232 1.00 52.05  ? 278 LYS F CG  1 
ATOM   16935 C  CD  . LYS F 2 280 ? 246.893 302.128 270.200 1.00 57.07  ? 278 LYS F CD  1 
ATOM   16936 C  CE  . LYS F 2 280 ? 246.914 302.714 271.603 1.00 61.02  ? 278 LYS F CE  1 
ATOM   16937 N  NZ  . LYS F 2 280 ? 245.650 302.448 272.341 1.00 55.76  ? 278 LYS F NZ  1 
ATOM   16938 N  N   . ARG F 2 281 ? 250.133 297.864 271.417 1.00 45.67  ? 279 ARG F N   1 
ATOM   16939 C  CA  . ARG F 2 281 ? 251.199 297.123 270.750 1.00 40.71  ? 279 ARG F CA  1 
ATOM   16940 C  C   . ARG F 2 281 ? 250.878 295.633 270.677 1.00 43.46  ? 279 ARG F C   1 
ATOM   16941 O  O   . ARG F 2 281 ? 251.082 294.992 269.637 1.00 43.15  ? 279 ARG F O   1 
ATOM   16942 C  CB  . ARG F 2 281 ? 252.523 297.361 271.478 1.00 42.76  ? 279 ARG F CB  1 
ATOM   16943 C  CG  . ARG F 2 281 ? 253.759 297.093 270.641 1.00 43.99  ? 279 ARG F CG  1 
ATOM   16944 C  CD  . ARG F 2 281 ? 254.963 296.803 271.519 1.00 44.14  ? 279 ARG F CD  1 
ATOM   16945 N  NE  . ARG F 2 281 ? 254.653 295.849 272.576 1.00 50.07  ? 279 ARG F NE  1 
ATOM   16946 C  CZ  . ARG F 2 281 ? 254.817 294.538 272.472 1.00 48.91  ? 279 ARG F CZ  1 
ATOM   16947 N  NH1 . ARG F 2 281 ? 255.287 293.986 271.366 1.00 49.83  ? 279 ARG F NH1 1 
ATOM   16948 N  NH2 . ARG F 2 281 ? 254.501 293.760 273.503 1.00 47.89  ? 279 ARG F NH2 1 
ATOM   16949 N  N   . ILE F 2 282 ? 250.366 295.063 271.769 1.00 43.84  ? 280 ILE F N   1 
ATOM   16950 C  CA  . ILE F 2 282 ? 250.028 293.641 271.761 1.00 40.70  ? 280 ILE F CA  1 
ATOM   16951 C  C   . ILE F 2 282 ? 248.876 293.366 270.798 1.00 40.01  ? 280 ILE F C   1 
ATOM   16952 O  O   . ILE F 2 282 ? 248.870 292.355 270.077 1.00 42.58  ? 280 ILE F O   1 
ATOM   16953 C  CB  . ILE F 2 282 ? 249.710 293.164 273.189 1.00 38.97  ? 280 ILE F CB  1 
ATOM   16954 C  CG1 . ILE F 2 282 ? 250.928 293.363 274.092 1.00 39.06  ? 280 ILE F CG1 1 
ATOM   16955 C  CG2 . ILE F 2 282 ? 249.293 291.705 273.179 1.00 38.52  ? 280 ILE F CG2 1 
ATOM   16956 C  CD1 . ILE F 2 282 ? 250.605 293.378 275.566 1.00 40.41  ? 280 ILE F CD1 1 
ATOM   16957 N  N   . ASP F 2 283 ? 247.878 294.254 270.772 1.00 37.99  ? 281 ASP F N   1 
ATOM   16958 C  CA  . ASP F 2 283 ? 246.775 294.088 269.833 1.00 35.79  ? 281 ASP F CA  1 
ATOM   16959 C  C   . ASP F 2 283 ? 247.268 294.163 268.394 1.00 37.95  ? 281 ASP F C   1 
ATOM   16960 O  O   . ASP F 2 283 ? 246.791 293.424 267.522 1.00 38.48  ? 281 ASP F O   1 
ATOM   16961 C  CB  . ASP F 2 283 ? 245.703 295.146 270.093 1.00 41.78  ? 281 ASP F CB  1 
ATOM   16962 C  CG  . ASP F 2 283 ? 244.609 294.648 271.013 1.00 46.88  ? 281 ASP F CG  1 
ATOM   16963 O  OD1 . ASP F 2 283 ? 244.225 293.466 270.895 1.00 47.67  ? 281 ASP F OD1 1 
ATOM   16964 O  OD2 . ASP F 2 283 ? 244.133 295.436 271.856 1.00 49.33  ? 281 ASP F OD2 1 
ATOM   16965 N  N   . LYS F 2 284 ? 248.223 295.056 268.126 1.00 39.40  ? 282 LYS F N   1 
ATOM   16966 C  CA  . LYS F 2 284 ? 248.827 295.114 266.802 1.00 36.52  ? 282 LYS F CA  1 
ATOM   16967 C  C   . LYS F 2 284 ? 249.556 293.820 266.475 1.00 37.11  ? 282 LYS F C   1 
ATOM   16968 O  O   . LYS F 2 284 ? 249.526 293.363 265.332 1.00 36.76  ? 282 LYS F O   1 
ATOM   16969 C  CB  . LYS F 2 284 ? 249.776 296.306 266.702 1.00 39.93  ? 282 LYS F CB  1 
ATOM   16970 C  CG  . LYS F 2 284 ? 249.233 297.450 265.867 1.00 43.30  ? 282 LYS F CG  1 
ATOM   16971 C  CD  . LYS F 2 284 ? 250.338 298.409 265.466 1.00 46.92  ? 282 LYS F CD  1 
ATOM   16972 C  CE  . LYS F 2 284 ? 251.377 297.714 264.604 1.00 50.06  ? 282 LYS F CE  1 
ATOM   16973 N  NZ  . LYS F 2 284 ? 250.761 297.039 263.427 1.00 48.92  ? 282 LYS F NZ  1 
ATOM   16974 N  N   . GLU F 2 285 ? 250.222 293.217 267.461 1.00 39.84  ? 283 GLU F N   1 
ATOM   16975 C  CA  . GLU F 2 285 ? 250.879 291.932 267.224 1.00 34.94  ? 283 GLU F CA  1 
ATOM   16976 C  C   . GLU F 2 285 ? 249.867 290.865 266.814 1.00 36.32  ? 283 GLU F C   1 
ATOM   16977 O  O   . GLU F 2 285 ? 250.096 290.094 265.871 1.00 40.06  ? 283 GLU F O   1 
ATOM   16978 C  CB  . GLU F 2 285 ? 251.635 291.486 268.476 1.00 39.01  ? 283 GLU F CB  1 
ATOM   16979 C  CG  . GLU F 2 285 ? 252.861 292.306 268.814 1.00 48.09  ? 283 GLU F CG  1 
ATOM   16980 C  CD  . GLU F 2 285 ? 253.636 291.720 269.979 1.00 54.22  ? 283 GLU F CD  1 
ATOM   16981 O  OE1 . GLU F 2 285 ? 253.002 291.355 270.992 1.00 47.96  ? 283 GLU F OE1 1 
ATOM   16982 O  OE2 . GLU F 2 285 ? 254.877 291.625 269.884 1.00 61.37  ? 283 GLU F OE2 1 
ATOM   16983 N  N   . LEU F 2 286 ? 248.742 290.800 267.528 1.00 31.99  ? 284 LEU F N   1 
ATOM   16984 C  CA  . LEU F 2 286 ? 247.723 289.799 267.211 1.00 30.16  ? 284 LEU F CA  1 
ATOM   16985 C  C   . LEU F 2 286 ? 247.139 290.028 265.818 1.00 33.88  ? 284 LEU F C   1 
ATOM   16986 O  O   . LEU F 2 286 ? 247.022 289.093 265.008 1.00 38.91  ? 284 LEU F O   1 
ATOM   16987 C  CB  . LEU F 2 286 ? 246.622 289.826 268.271 1.00 29.04  ? 284 LEU F CB  1 
ATOM   16988 C  CG  . LEU F 2 286 ? 246.994 289.292 269.656 1.00 29.75  ? 284 LEU F CG  1 
ATOM   16989 C  CD1 . LEU F 2 286 ? 246.014 289.789 270.703 1.00 27.93  ? 284 LEU F CD1 1 
ATOM   16990 C  CD2 . LEU F 2 286 ? 247.050 287.776 269.656 1.00 27.77  ? 284 LEU F CD2 1 
ATOM   16991 N  N   . GLN F 2 287 ? 246.773 291.277 265.519 1.00 36.01  ? 285 GLN F N   1 
ATOM   16992 C  CA  . GLN F 2 287 ? 246.261 291.590 264.191 1.00 34.75  ? 285 GLN F CA  1 
ATOM   16993 C  C   . GLN F 2 287 ? 247.306 291.319 263.118 1.00 37.56  ? 285 GLN F C   1 
ATOM   16994 O  O   . GLN F 2 287 ? 246.958 290.935 261.997 1.00 38.61  ? 285 GLN F O   1 
ATOM   16995 C  CB  . GLN F 2 287 ? 245.804 293.047 264.135 1.00 37.53  ? 285 GLN F CB  1 
ATOM   16996 C  CG  . GLN F 2 287 ? 244.950 293.381 262.925 1.00 40.50  ? 285 GLN F CG  1 
ATOM   16997 C  CD  . GLN F 2 287 ? 243.795 292.418 262.746 1.00 51.16  ? 285 GLN F CD  1 
ATOM   16998 O  OE1 . GLN F 2 287 ? 243.671 291.764 261.711 1.00 50.45  ? 285 GLN F OE1 1 
ATOM   16999 N  NE2 . GLN F 2 287 ? 242.940 292.325 263.758 1.00 49.61  ? 285 GLN F NE2 1 
ATOM   17000 N  N   . GLY F 2 288 ? 248.585 291.511 263.440 1.00 34.29  ? 286 GLY F N   1 
ATOM   17001 C  CA  . GLY F 2 288 ? 249.633 291.234 262.478 1.00 33.34  ? 286 GLY F CA  1 
ATOM   17002 C  C   . GLY F 2 288 ? 249.747 289.759 262.162 1.00 35.92  ? 286 GLY F C   1 
ATOM   17003 O  O   . GLY F 2 288 ? 249.940 289.379 261.007 1.00 42.13  ? 286 GLY F O   1 
ATOM   17004 N  N   . PHE F 2 289 ? 249.634 288.907 263.181 1.00 34.84  ? 287 PHE F N   1 
ATOM   17005 C  CA  . PHE F 2 289 ? 249.578 287.472 262.913 1.00 30.45  ? 287 PHE F CA  1 
ATOM   17006 C  C   . PHE F 2 289 ? 248.400 287.138 262.004 1.00 33.68  ? 287 PHE F C   1 
ATOM   17007 O  O   . PHE F 2 289 ? 248.554 286.448 260.981 1.00 35.65  ? 287 PHE F O   1 
ATOM   17008 C  CB  . PHE F 2 289 ? 249.487 286.683 264.219 1.00 30.11  ? 287 PHE F CB  1 
ATOM   17009 C  CG  . PHE F 2 289 ? 249.347 285.204 264.012 1.00 29.66  ? 287 PHE F CG  1 
ATOM   17010 C  CD1 . PHE F 2 289 ? 250.454 284.421 263.732 1.00 29.80  ? 287 PHE F CD1 1 
ATOM   17011 C  CD2 . PHE F 2 289 ? 248.105 284.598 264.078 1.00 25.27  ? 287 PHE F CD2 1 
ATOM   17012 C  CE1 . PHE F 2 289 ? 250.324 283.064 263.530 1.00 27.83  ? 287 PHE F CE1 1 
ATOM   17013 C  CE2 . PHE F 2 289 ? 247.970 283.242 263.876 1.00 25.15  ? 287 PHE F CE2 1 
ATOM   17014 C  CZ  . PHE F 2 289 ? 249.081 282.474 263.602 1.00 27.55  ? 287 PHE F CZ  1 
ATOM   17015 N  N   . ARG F 2 290 ? 247.213 287.645 262.349 1.00 35.47  ? 288 ARG F N   1 
ATOM   17016 C  CA  . ARG F 2 290 ? 246.033 287.353 261.539 1.00 33.08  ? 288 ARG F CA  1 
ATOM   17017 C  C   . ARG F 2 290 ? 246.237 287.782 260.090 1.00 34.96  ? 288 ARG F C   1 
ATOM   17018 O  O   . ARG F 2 290 ? 245.921 287.035 259.158 1.00 36.83  ? 288 ARG F O   1 
ATOM   17019 C  CB  . ARG F 2 290 ? 244.796 288.033 262.125 1.00 37.11  ? 288 ARG F CB  1 
ATOM   17020 C  CG  . ARG F 2 290 ? 244.560 287.764 263.593 1.00 40.87  ? 288 ARG F CG  1 
ATOM   17021 C  CD  . ARG F 2 290 ? 243.170 288.217 263.999 1.00 44.20  ? 288 ARG F CD  1 
ATOM   17022 N  NE  . ARG F 2 290 ? 242.142 287.632 263.147 1.00 47.19  ? 288 ARG F NE  1 
ATOM   17023 C  CZ  . ARG F 2 290 ? 241.003 287.119 263.590 1.00 46.87  ? 288 ARG F CZ  1 
ATOM   17024 N  NH1 . ARG F 2 290 ? 240.710 287.098 264.880 1.00 43.30  ? 288 ARG F NH1 1 
ATOM   17025 N  NH2 . ARG F 2 290 ? 240.138 286.609 262.718 1.00 41.77  ? 288 ARG F NH2 1 
ATOM   17026 N  N   . ASP F 2 291 ? 246.761 288.991 259.881 1.00 35.31  ? 289 ASP F N   1 
ATOM   17027 C  CA  . ASP F 2 291 ? 246.947 289.492 258.524 1.00 34.73  ? 289 ASP F CA  1 
ATOM   17028 C  C   . ASP F 2 291 ? 248.022 288.708 257.780 1.00 38.08  ? 289 ASP F C   1 
ATOM   17029 O  O   . ASP F 2 291 ? 247.852 288.382 256.599 1.00 40.98  ? 289 ASP F O   1 
ATOM   17030 C  CB  . ASP F 2 291 ? 247.293 290.979 258.557 1.00 39.20  ? 289 ASP F CB  1 
ATOM   17031 C  CG  . ASP F 2 291 ? 246.175 291.825 259.134 1.00 48.67  ? 289 ASP F CG  1 
ATOM   17032 O  OD1 . ASP F 2 291 ? 245.017 291.357 259.148 1.00 46.05  ? 289 ASP F OD1 1 
ATOM   17033 O  OD2 . ASP F 2 291 ? 246.455 292.960 259.571 1.00 50.63  ? 289 ASP F OD2 1 
ATOM   17034 N  N   . GLY F 2 292 ? 249.131 288.393 258.447 1.00 35.63  ? 290 GLY F N   1 
ATOM   17035 C  CA  . GLY F 2 292 ? 250.204 287.653 257.817 1.00 33.47  ? 290 GLY F CA  1 
ATOM   17036 C  C   . GLY F 2 292 ? 249.862 286.222 257.488 1.00 33.74  ? 290 GLY F C   1 
ATOM   17037 O  O   . GLY F 2 292 ? 250.600 285.589 256.725 1.00 35.93  ? 290 GLY F O   1 
ATOM   17038 N  N   . LEU F 2 293 ? 248.771 285.693 258.046 1.00 34.52  ? 291 LEU F N   1 
ATOM   17039 C  CA  . LEU F 2 293 ? 248.337 284.357 257.649 1.00 29.43  ? 291 LEU F CA  1 
ATOM   17040 C  C   . LEU F 2 293 ? 248.070 284.253 256.150 1.00 26.05  ? 291 LEU F C   1 
ATOM   17041 O  O   . LEU F 2 293 ? 248.340 283.209 255.547 1.00 27.89  ? 291 LEU F O   1 
ATOM   17042 C  CB  . LEU F 2 293 ? 247.086 283.954 258.426 1.00 25.71  ? 291 LEU F CB  1 
ATOM   17043 C  CG  . LEU F 2 293 ? 247.310 283.433 259.842 1.00 25.95  ? 291 LEU F CG  1 
ATOM   17044 C  CD1 . LEU F 2 293 ? 245.977 283.127 260.496 1.00 28.99  ? 291 LEU F CD1 1 
ATOM   17045 C  CD2 . LEU F 2 293 ? 248.201 282.204 259.820 1.00 24.52  ? 291 LEU F CD2 1 
ATOM   17046 N  N   . PHE F 2 294 ? 247.539 285.305 255.530 1.00 28.38  ? 292 PHE F N   1 
ATOM   17047 C  CA  . PHE F 2 294 ? 247.007 285.217 254.177 1.00 28.84  ? 292 PHE F CA  1 
ATOM   17048 C  C   . PHE F 2 294 ? 247.728 286.172 253.234 1.00 30.72  ? 292 PHE F C   1 
ATOM   17049 O  O   . PHE F 2 294 ? 248.416 287.103 253.660 1.00 40.87  ? 292 PHE F O   1 
ATOM   17050 C  CB  . PHE F 2 294 ? 245.502 285.497 254.171 1.00 26.57  ? 292 PHE F CB  1 
ATOM   17051 C  CG  . PHE F 2 294 ? 244.736 284.641 255.131 1.00 27.88  ? 292 PHE F CG  1 
ATOM   17052 C  CD1 . PHE F 2 294 ? 244.555 283.292 254.881 1.00 25.06  ? 292 PHE F CD1 1 
ATOM   17053 C  CD2 . PHE F 2 294 ? 244.226 285.175 256.299 1.00 28.87  ? 292 PHE F CD2 1 
ATOM   17054 C  CE1 . PHE F 2 294 ? 243.865 282.499 255.768 1.00 25.69  ? 292 PHE F CE1 1 
ATOM   17055 C  CE2 . PHE F 2 294 ? 243.536 284.385 257.191 1.00 26.84  ? 292 PHE F CE2 1 
ATOM   17056 C  CZ  . PHE F 2 294 ? 243.354 283.047 256.925 1.00 27.19  ? 292 PHE F CZ  1 
ATOM   17057 N  N   . VAL F 2 295 ? 247.554 285.925 251.933 1.00 31.13  ? 293 VAL F N   1 
ATOM   17058 C  CA  . VAL F 2 295 ? 248.333 286.592 250.898 1.00 39.71  ? 293 VAL F CA  1 
ATOM   17059 C  C   . VAL F 2 295 ? 247.480 287.161 249.776 1.00 44.62  ? 293 VAL F C   1 
ATOM   17060 O  O   . VAL F 2 295 ? 248.029 287.703 248.816 1.00 50.13  ? 293 VAL F O   1 
ATOM   17061 C  CB  . VAL F 2 295 ? 249.400 285.642 250.315 1.00 42.04  ? 293 VAL F CB  1 
ATOM   17062 C  CG1 . VAL F 2 295 ? 250.273 285.084 251.424 1.00 34.34  ? 293 VAL F CG1 1 
ATOM   17063 C  CG2 . VAL F 2 295 ? 248.736 284.518 249.533 1.00 31.33  ? 293 VAL F CG2 1 
ATOM   17064 N  N   . THR F 2 296 ? 246.153 287.060 249.854 1.00 46.83  ? 294 THR F N   1 
ATOM   17065 C  CA  . THR F 2 296 ? 245.319 287.489 248.737 1.00 48.56  ? 294 THR F CA  1 
ATOM   17066 C  C   . THR F 2 296 ? 245.363 288.997 248.517 1.00 55.51  ? 294 THR F C   1 
ATOM   17067 O  O   . THR F 2 296 ? 245.064 289.458 247.411 1.00 56.18  ? 294 THR F O   1 
ATOM   17068 C  CB  . THR F 2 296 ? 243.875 287.031 248.951 1.00 42.28  ? 294 THR F CB  1 
ATOM   17069 O  OG1 . THR F 2 296 ? 243.746 285.660 248.559 1.00 36.57  ? 294 THR F OG1 1 
ATOM   17070 C  CG2 . THR F 2 296 ? 242.916 287.869 248.127 1.00 50.98  ? 294 THR F CG2 1 
ATOM   17071 N  N   . GLN F 2 297 ? 245.750 289.772 249.528 1.00 57.53  ? 295 GLN F N   1 
ATOM   17072 C  CA  . GLN F 2 297 ? 245.803 291.223 249.422 1.00 63.07  ? 295 GLN F CA  1 
ATOM   17073 C  C   . GLN F 2 297 ? 247.198 291.744 249.098 1.00 66.80  ? 295 GLN F C   1 
ATOM   17074 O  O   . GLN F 2 297 ? 247.413 292.959 249.115 1.00 75.19  ? 295 GLN F O   1 
ATOM   17075 C  CB  . GLN F 2 297 ? 245.292 291.866 250.711 1.00 66.58  ? 295 GLN F CB  1 
ATOM   17076 C  CG  . GLN F 2 297 ? 243.923 291.372 251.143 1.00 71.15  ? 295 GLN F CG  1 
ATOM   17077 C  CD  . GLN F 2 297 ? 243.512 291.907 252.498 1.00 81.17  ? 295 GLN F CD  1 
ATOM   17078 O  OE1 . GLN F 2 297 ? 244.222 292.711 253.102 1.00 80.63  ? 295 GLN F OE1 1 
ATOM   17079 N  NE2 . GLN F 2 297 ? 242.359 291.462 252.984 1.00 78.88  ? 295 GLN F NE2 1 
ATOM   17080 N  N   . ASP F 2 298 ? 248.145 290.859 248.803 1.00 66.61  ? 296 ASP F N   1 
ATOM   17081 C  CA  . ASP F 2 298 ? 249.500 291.263 248.432 1.00 71.70  ? 296 ASP F CA  1 
ATOM   17082 C  C   . ASP F 2 298 ? 249.548 291.395 246.915 1.00 79.31  ? 296 ASP F C   1 
ATOM   17083 O  O   . ASP F 2 298 ? 249.575 290.397 246.192 1.00 76.98  ? 296 ASP F O   1 
ATOM   17084 C  CB  . ASP F 2 298 ? 250.525 290.257 248.944 1.00 71.40  ? 296 ASP F CB  1 
ATOM   17085 C  CG  . ASP F 2 298 ? 250.396 289.995 250.436 1.00 70.95  ? 296 ASP F CG  1 
ATOM   17086 O  OD1 . ASP F 2 298 ? 251.203 289.206 250.971 1.00 65.06  ? 296 ASP F OD1 1 
ATOM   17087 O  OD2 . ASP F 2 298 ? 249.494 290.577 251.076 1.00 72.28  ? 296 ASP F OD2 1 
ATOM   17088 N  N   . THR F 2 299 ? 249.557 292.637 246.429 1.00 85.25  ? 297 THR F N   1 
ATOM   17089 C  CA  . THR F 2 299 ? 249.523 292.927 245.000 1.00 85.78  ? 297 THR F CA  1 
ATOM   17090 C  C   . THR F 2 299 ? 250.888 293.342 244.458 1.00 86.16  ? 297 THR F C   1 
ATOM   17091 O  O   . THR F 2 299 ? 250.968 294.145 243.524 1.00 88.70  ? 297 THR F O   1 
ATOM   17092 C  CB  . THR F 2 299 ? 248.482 294.007 244.705 1.00 88.70  ? 297 THR F CB  1 
ATOM   17093 O  OG1 . THR F 2 299 ? 248.397 294.223 243.291 1.00 88.69  ? 297 THR F OG1 1 
ATOM   17094 C  CG2 . THR F 2 299 ? 248.856 295.307 245.394 1.00 95.65  ? 297 THR F CG2 1 
ATOM   17095 N  N   . THR F 2 300 ? 251.966 292.806 245.028 1.00 84.77  ? 298 THR F N   1 
ATOM   17096 C  CA  . THR F 2 300 ? 253.317 293.111 244.579 1.00 88.37  ? 298 THR F CA  1 
ATOM   17097 C  C   . THR F 2 300 ? 253.785 292.199 243.452 1.00 84.89  ? 298 THR F C   1 
ATOM   17098 O  O   . THR F 2 300 ? 254.996 292.056 243.246 1.00 83.25  ? 298 THR F O   1 
ATOM   17099 C  CB  . THR F 2 300 ? 254.295 293.028 245.753 1.00 91.80  ? 298 THR F CB  1 
ATOM   17100 O  OG1 . THR F 2 300 ? 254.790 291.688 245.871 1.00 85.23  ? 298 THR F OG1 1 
ATOM   17101 C  CG2 . THR F 2 300 ? 253.604 293.423 247.048 1.00 92.00  ? 298 THR F CG2 1 
ATOM   17102 N  N   . TRP F 2 301 ? 252.859 291.583 242.726 1.00 78.64  ? 299 TRP F N   1 
ATOM   17103 C  CA  . TRP F 2 301 ? 253.202 290.679 241.636 1.00 77.31  ? 299 TRP F CA  1 
ATOM   17104 C  C   . TRP F 2 301 ? 253.104 291.382 240.286 1.00 74.22  ? 299 TRP F C   1 
ATOM   17105 O  O   . TRP F 2 301 ? 252.174 292.150 240.039 1.00 69.29  ? 299 TRP F O   1 
ATOM   17106 C  CB  . TRP F 2 301 ? 252.290 289.450 241.659 1.00 70.41  ? 299 TRP F CB  1 
ATOM   17107 C  CG  . TRP F 2 301 ? 250.850 289.777 241.926 1.00 65.32  ? 299 TRP F CG  1 
ATOM   17108 C  CD1 . TRP F 2 301 ? 250.255 289.912 243.145 1.00 64.60  ? 299 TRP F CD1 1 
ATOM   17109 C  CD2 . TRP F 2 301 ? 249.826 290.009 240.952 1.00 61.99  ? 299 TRP F CD2 1 
ATOM   17110 N  NE1 . TRP F 2 301 ? 248.925 290.216 242.992 1.00 60.82  ? 299 TRP F NE1 1 
ATOM   17111 C  CE2 . TRP F 2 301 ? 248.636 290.280 241.655 1.00 58.52  ? 299 TRP F CE2 1 
ATOM   17112 C  CE3 . TRP F 2 301 ? 249.799 290.015 239.555 1.00 62.18  ? 299 TRP F CE3 1 
ATOM   17113 C  CZ2 . TRP F 2 301 ? 247.433 290.552 241.008 1.00 52.94  ? 299 TRP F CZ2 1 
ATOM   17114 C  CZ3 . TRP F 2 301 ? 248.604 290.286 238.915 1.00 57.63  ? 299 TRP F CZ3 1 
ATOM   17115 C  CH2 . TRP F 2 301 ? 247.438 290.552 239.641 1.00 52.12  ? 299 TRP F CH2 1 
HETATM 17116 C  C1  . MAN G 3 .   ? 245.335 237.831 247.770 1.00 34.62  ? 1   MAN G C1  1 
HETATM 17117 C  C2  . MAN G 3 .   ? 245.621 236.507 248.464 1.00 35.85  ? 1   MAN G C2  1 
HETATM 17118 C  C3  . MAN G 3 .   ? 244.641 236.351 249.620 1.00 36.31  ? 1   MAN G C3  1 
HETATM 17119 C  C4  . MAN G 3 .   ? 244.781 237.523 250.583 1.00 36.01  ? 1   MAN G C4  1 
HETATM 17120 C  C5  . MAN G 3 .   ? 244.760 238.861 249.835 1.00 34.29  ? 1   MAN G C5  1 
HETATM 17121 C  C6  . MAN G 3 .   ? 245.273 239.965 250.727 1.00 31.20  ? 1   MAN G C6  1 
HETATM 17122 O  O2  . MAN G 3 .   ? 246.956 236.619 248.896 1.00 43.01  ? 1   MAN G O2  1 
HETATM 17123 O  O3  . MAN G 3 .   ? 244.891 235.119 250.250 1.00 40.94  ? 1   MAN G O3  1 
HETATM 17124 O  O4  . MAN G 3 .   ? 243.673 237.446 251.453 1.00 38.60  ? 1   MAN G O4  1 
HETATM 17125 O  O5  . MAN G 3 .   ? 245.586 238.855 248.682 1.00 41.63  ? 1   MAN G O5  1 
HETATM 17126 O  O6  . MAN G 3 .   ? 245.014 241.195 250.104 1.00 37.02  ? 1   MAN G O6  1 
HETATM 17127 H  H1  . MAN G 3 .   ? 245.981 237.971 247.060 1.00 35.42  ? 1   MAN G H1  1 
HETATM 17128 H  H2  . MAN G 3 .   ? 245.505 235.784 247.829 1.00 37.39  ? 1   MAN G H2  1 
HETATM 17129 H  H3  . MAN G 3 .   ? 243.738 236.365 249.269 1.00 36.82  ? 1   MAN G H3  1 
HETATM 17130 H  H4  . MAN G 3 .   ? 245.623 237.439 251.056 1.00 36.78  ? 1   MAN G H4  1 
HETATM 17131 H  H5  . MAN G 3 .   ? 243.842 239.058 249.594 1.00 33.87  ? 1   MAN G H5  1 
HETATM 17132 H  H61 . MAN G 3 .   ? 246.223 239.828 250.868 1.00 31.07  ? 1   MAN G H61 1 
HETATM 17133 H  H62 . MAN G 3 .   ? 244.842 239.897 251.591 1.00 31.99  ? 1   MAN G H62 1 
HETATM 17134 H  HO3 . MAN G 3 .   ? 244.386 235.063 250.931 1.00 40.98  ? 1   MAN G HO3 1 
HETATM 17135 H  HO6 . MAN G 3 .   ? 245.424 241.203 249.359 1.00 32.20  ? 1   MAN G HO6 1 
HETATM 17136 C  C1  . GCU G 3 .   ? 247.597 235.340 249.112 1.00 42.72  ? 2   GCU G C1  1 
HETATM 17137 C  C2  . GCU G 3 .   ? 249.011 235.636 249.628 1.00 46.17  ? 2   GCU G C2  1 
HETATM 17138 C  C3  . GCU G 3 .   ? 249.873 236.274 248.548 1.00 47.73  ? 2   GCU G C3  1 
HETATM 17139 C  C4  . GCU G 3 .   ? 249.884 235.354 247.340 1.00 51.78  ? 2   GCU G C4  1 
HETATM 17140 C  C5  . GCU G 3 .   ? 248.435 235.149 246.886 1.00 52.65  ? 2   GCU G C5  1 
HETATM 17141 C  C6  . GCU G 3 .   ? 248.368 234.259 245.631 1.00 55.57  ? 2   GCU G C6  1 
HETATM 17142 O  O2  . GCU G 3 .   ? 248.897 236.440 250.773 1.00 45.79  ? 2   GCU G O2  1 
HETATM 17143 O  O3  . GCU G 3 .   ? 251.153 236.465 249.108 1.00 46.49  ? 2   GCU G O3  1 
HETATM 17144 O  O4  . GCU G 3 .   ? 250.664 235.891 246.301 1.00 57.40  ? 2   GCU G O4  1 
HETATM 17145 O  O5  . GCU G 3 .   ? 247.680 234.576 247.933 1.00 51.21  ? 2   GCU G O5  1 
HETATM 17146 O  O6A . GCU G 3 .   ? 248.847 234.798 244.598 1.00 55.36  ? 2   GCU G O6A 1 
HETATM 17147 O  O6B . GCU G 3 .   ? 247.878 233.134 245.717 1.00 55.57  ? 2   GCU G O6B 1 
HETATM 17148 H  H1  . GCU G 3 .   ? 247.110 234.797 249.749 1.00 43.55  ? 2   GCU G H1  1 
HETATM 17149 H  H2  . GCU G 3 .   ? 249.404 234.778 249.850 1.00 47.30  ? 2   GCU G H2  1 
HETATM 17150 H  H3  . GCU G 3 .   ? 249.484 237.123 248.284 1.00 47.82  ? 2   GCU G H3  1 
HETATM 17151 H  H4  . GCU G 3 .   ? 250.215 234.494 247.641 1.00 50.99  ? 2   GCU G H4  1 
HETATM 17152 H  H5  . GCU G 3 .   ? 248.076 236.015 246.640 1.00 49.00  ? 2   GCU G H5  1 
HETATM 17153 H  HO2 . GCU G 3 .   ? 248.517 237.164 250.540 1.00 42.82  ? 2   GCU G HO2 1 
HETATM 17154 H  HO3 . GCU G 3 .   ? 251.494 235.702 249.261 1.00 47.31  ? 2   GCU G HO3 1 
HETATM 17155 C  C1  . GLC G 3 .   ? 252.044 235.450 246.403 1.00 62.74  ? 3   GLC G C1  1 
HETATM 17156 C  C2  . GLC G 3 .   ? 252.764 235.912 245.120 1.00 64.79  ? 3   GLC G C2  1 
HETATM 17157 C  C3  . GLC G 3 .   ? 253.515 234.792 244.415 1.00 67.97  ? 3   GLC G C3  1 
HETATM 17158 C  C4  . GLC G 3 .   ? 254.287 233.982 245.441 1.00 70.04  ? 3   GLC G C4  1 
HETATM 17159 C  C5  . GLC G 3 .   ? 253.269 233.267 246.325 1.00 69.64  ? 3   GLC G C5  1 
HETATM 17160 C  C6  . GLC G 3 .   ? 253.822 232.911 247.698 1.00 70.27  ? 3   GLC G C6  1 
HETATM 17161 O  O2  . GLC G 3 .   ? 251.813 236.510 244.282 1.00 64.39  ? 3   GLC G O2  1 
HETATM 17162 O  O3  . GLC G 3 .   ? 254.348 235.306 243.399 1.00 69.41  ? 3   GLC G O3  1 
HETATM 17163 O  O4  . GLC G 3 .   ? 255.083 233.006 244.817 1.00 75.63  ? 3   GLC G O4  1 
HETATM 17164 O  O5  . GLC G 3 .   ? 252.108 234.044 246.579 1.00 67.07  ? 3   GLC G O5  1 
HETATM 17165 O  O6  . GLC G 3 .   ? 254.953 232.078 247.658 1.00 76.73  ? 3   GLC G O6  1 
HETATM 17166 H  H1  . GLC G 3 .   ? 252.464 235.841 247.185 1.00 61.90  ? 3   GLC G H1  1 
HETATM 17167 H  H2  . GLC G 3 .   ? 253.425 236.559 245.410 1.00 64.05  ? 3   GLC G H2  1 
HETATM 17168 H  H3  . GLC G 3 .   ? 252.892 234.201 243.963 1.00 66.85  ? 3   GLC G H3  1 
HETATM 17169 H  H4  . GLC G 3 .   ? 254.813 234.584 245.990 1.00 69.00  ? 3   GLC G H4  1 
HETATM 17170 H  H5  . GLC G 3 .   ? 253.025 232.446 245.868 1.00 69.09  ? 3   GLC G H5  1 
HETATM 17171 H  H61 . GLC G 3 .   ? 253.109 232.515 248.222 1.00 68.88  ? 3   GLC G H61 1 
HETATM 17172 H  H62 . GLC G 3 .   ? 254.087 233.727 248.149 1.00 67.37  ? 3   GLC G H62 1 
HETATM 17173 H  HO2 . GLC G 3 .   ? 251.245 235.916 244.063 1.00 62.72  ? 3   GLC G HO2 1 
HETATM 17174 H  HO3 . GLC G 3 .   ? 254.923 235.822 243.752 1.00 67.49  ? 3   GLC G HO3 1 
HETATM 17175 H  HO6 . GLC G 3 .   ? 254.774 231.411 247.163 1.00 76.01  ? 3   GLC G HO6 1 
HETATM 17176 C  C1  . FUC G 3 .   ? 256.445 233.045 245.306 1.00 78.33  ? 4   FUC G C1  1 
HETATM 17177 C  C2  . FUC G 3 .   ? 257.122 231.727 244.904 1.00 78.75  ? 4   FUC G C2  1 
HETATM 17178 C  C3  . FUC G 3 .   ? 257.272 231.649 243.388 1.00 79.25  ? 4   FUC G C3  1 
HETATM 17179 C  C4  . FUC G 3 .   ? 258.059 232.859 242.888 1.00 79.82  ? 4   FUC G C4  1 
HETATM 17180 C  C5  . FUC G 3 .   ? 257.334 234.124 243.349 1.00 77.29  ? 4   FUC G C5  1 
HETATM 17181 C  C6  . FUC G 3 .   ? 258.073 235.396 242.993 1.00 76.94  ? 4   FUC G C6  1 
HETATM 17182 O  O2  . FUC G 3 .   ? 256.362 230.667 245.421 1.00 77.39  ? 4   FUC G O2  1 
HETATM 17183 O  O3  . FUC G 3 .   ? 257.887 230.420 243.086 1.00 82.72  ? 4   FUC G O3  1 
HETATM 17184 O  O4  . FUC G 3 .   ? 259.374 232.771 243.378 1.00 81.54  ? 4   FUC G O4  1 
HETATM 17185 O  O5  . FUC G 3 .   ? 257.162 234.126 244.761 1.00 77.64  ? 4   FUC G O5  1 
HETATM 17186 H  H1  . FUC G 3 .   ? 256.474 233.166 246.268 1.00 75.87  ? 4   FUC G H1  1 
HETATM 17187 H  H2  . FUC G 3 .   ? 258.007 231.739 245.299 1.00 78.68  ? 4   FUC G H2  1 
HETATM 17188 H  H3  . FUC G 3 .   ? 256.391 231.696 242.987 1.00 78.00  ? 4   FUC G H3  1 
HETATM 17189 H  H4  . FUC G 3 .   ? 258.048 232.855 241.918 1.00 79.47  ? 4   FUC G H4  1 
HETATM 17190 H  H5  . FUC G 3 .   ? 256.472 234.137 242.905 1.00 76.41  ? 4   FUC G H5  1 
HETATM 17191 H  H61 . FUC G 3 .   ? 258.925 235.440 243.455 1.00 77.68  ? 4   FUC G H61 1 
HETATM 17192 H  H62 . FUC G 3 .   ? 257.566 236.188 243.228 1.00 76.65  ? 4   FUC G H62 1 
HETATM 17193 H  H63 . FUC G 3 .   ? 258.255 235.422 242.040 1.00 77.35  ? 4   FUC G H63 1 
HETATM 17194 H  HO2 . FUC G 3 .   ? 255.601 230.685 245.041 1.00 77.81  ? 4   FUC G HO2 1 
HETATM 17195 H  HO3 . FUC G 3 .   ? 257.475 229.801 243.498 1.00 81.38  ? 4   FUC G HO3 1 
HETATM 17196 H  HO4 . FUC G 3 .   ? 259.375 232.980 244.202 1.00 80.23  ? 4   FUC G HO4 1 
HETATM 17197 C  C1  . RAM G 3 .   ? 244.048 237.469 252.845 1.00 38.75  ? 5   RAM G C1  1 
HETATM 17198 C  C2  . RAM G 3 .   ? 242.931 238.200 253.599 1.00 42.50  ? 5   RAM G C2  1 
HETATM 17199 C  C3  . RAM G 3 .   ? 242.417 237.398 254.786 1.00 46.41  ? 5   RAM G C3  1 
HETATM 17200 C  C4  . RAM G 3 .   ? 242.023 235.972 254.349 1.00 44.29  ? 5   RAM G C4  1 
HETATM 17201 C  C5  . RAM G 3 .   ? 243.004 235.407 253.306 1.00 43.59  ? 5   RAM G C5  1 
HETATM 17202 C  C6  . RAM G 3 .   ? 243.369 233.964 253.569 1.00 43.08  ? 5   RAM G C6  1 
HETATM 17203 O  O2  . RAM G 3 .   ? 243.447 239.447 253.981 1.00 41.11  ? 5   RAM G O2  1 
HETATM 17204 O  O3  . RAM G 3 .   ? 243.421 237.413 255.771 1.00 52.97  ? 5   RAM G O3  1 
HETATM 17205 O  O4  . RAM G 3 .   ? 240.714 236.033 253.834 1.00 46.34  ? 5   RAM G O4  1 
HETATM 17206 O  O5  . RAM G 3 .   ? 244.198 236.163 253.330 1.00 44.06  ? 5   RAM G O5  1 
HETATM 17207 H  H1  . RAM G 3 .   ? 244.900 237.912 252.983 1.00 38.23  ? 5   RAM G H1  1 
HETATM 17208 H  H2  . RAM G 3 .   ? 242.181 238.312 252.994 1.00 40.34  ? 5   RAM G H2  1 
HETATM 17209 H  H3  . RAM G 3 .   ? 241.612 237.825 255.117 1.00 44.22  ? 5   RAM G H3  1 
HETATM 17210 H  H4  . RAM G 3 .   ? 242.054 235.404 255.135 1.00 45.36  ? 5   RAM G H4  1 
HETATM 17211 H  H5  . RAM G 3 .   ? 242.580 235.467 252.436 1.00 43.05  ? 5   RAM G H5  1 
HETATM 17212 H  H61 . RAM G 3 .   ? 243.971 233.622 252.890 1.00 43.30  ? 5   RAM G H61 1 
HETATM 17213 H  H62 . RAM G 3 .   ? 242.578 233.404 253.593 1.00 44.80  ? 5   RAM G H62 1 
HETATM 17214 H  H63 . RAM G 3 .   ? 243.817 233.881 254.425 1.00 44.12  ? 5   RAM G H63 1 
HETATM 17215 H  HO2 . RAM G 3 .   ? 243.863 239.781 253.322 1.00 37.42  ? 5   RAM G HO2 1 
HETATM 17216 H  HO3 . RAM G 3 .   ? 243.523 238.216 256.034 1.00 46.88  ? 5   RAM G HO3 1 
HETATM 17217 H  HO4 . RAM G 3 .   ? 240.719 236.495 253.120 1.00 43.18  ? 5   RAM G HO4 1 
HETATM 17218 C  C1  . MAN H 3 .   ? 253.855 236.033 262.932 1.00 46.01  ? 1   MAN H C1  1 
HETATM 17219 C  C2  . MAN H 3 .   ? 253.565 235.132 261.720 1.00 46.43  ? 1   MAN H C2  1 
HETATM 17220 C  C3  . MAN H 3 .   ? 252.417 234.189 262.045 1.00 50.08  ? 1   MAN H C3  1 
HETATM 17221 C  C4  . MAN H 3 .   ? 252.912 233.373 263.233 1.00 53.08  ? 1   MAN H C4  1 
HETATM 17222 C  C5  . MAN H 3 .   ? 252.943 234.353 264.403 1.00 51.88  ? 1   MAN H C5  1 
HETATM 17223 C  C6  . MAN H 3 .   ? 253.285 233.671 265.706 1.00 54.22  ? 1   MAN H C6  1 
HETATM 17224 O  O2  . MAN H 3 .   ? 254.670 234.302 261.440 1.00 52.06  ? 1   MAN H O2  1 
HETATM 17225 O  O3  . MAN H 3 .   ? 252.138 233.416 260.904 1.00 52.50  ? 1   MAN H O3  1 
HETATM 17226 O  O4  . MAN H 3 .   ? 252.155 232.196 263.449 1.00 55.14  ? 1   MAN H O4  1 
HETATM 17227 O  O5  . MAN H 3 .   ? 253.953 235.315 264.134 1.00 53.34  ? 1   MAN H O5  1 
HETATM 17228 O  O6  . MAN H 3 .   ? 253.289 234.637 266.728 1.00 55.36  ? 1   MAN H O6  1 
HETATM 17229 H  H1  . MAN H 3 .   ? 254.719 236.460 262.827 1.00 44.87  ? 1   MAN H H1  1 
HETATM 17230 H  H2  . MAN H 3 .   ? 253.330 235.688 260.960 1.00 45.87  ? 1   MAN H H2  1 
HETATM 17231 H  H3  . MAN H 3 .   ? 251.648 234.713 262.319 1.00 49.23  ? 1   MAN H H3  1 
HETATM 17232 H  H4  . MAN H 3 .   ? 253.826 233.106 263.061 1.00 52.84  ? 1   MAN H H4  1 
HETATM 17233 H  H5  . MAN H 3 .   ? 252.073 234.773 264.486 1.00 50.99  ? 1   MAN H H5  1 
HETATM 17234 H  H61 . MAN H 3 .   ? 254.153 233.247 265.613 1.00 52.05  ? 1   MAN H H61 1 
HETATM 17235 H  H62 . MAN H 3 .   ? 252.637 232.969 265.870 1.00 53.81  ? 1   MAN H H62 1 
HETATM 17236 H  HO3 . MAN H 3 .   ? 252.875 233.136 260.587 1.00 51.90  ? 1   MAN H HO3 1 
HETATM 17237 H  HO6 . MAN H 3 .   ? 252.534 235.027 266.724 1.00 53.38  ? 1   MAN H HO6 1 
HETATM 17238 C  C1  . GCU H 3 .   ? 255.846 234.944 260.923 1.00 51.98  ? 2   GCU H C1  1 
HETATM 17239 C  C2  . GCU H 3 .   ? 256.343 234.135 259.715 1.00 52.42  ? 2   GCU H C2  1 
HETATM 17240 C  C3  . GCU H 3 .   ? 256.932 232.786 260.127 1.00 53.77  ? 2   GCU H C3  1 
HETATM 17241 C  C4  . GCU H 3 .   ? 258.006 233.052 261.174 1.00 55.59  ? 2   GCU H C4  1 
HETATM 17242 C  C5  . GCU H 3 .   ? 257.266 233.708 262.352 1.00 53.51  ? 2   GCU H C5  1 
HETATM 17243 C  C6  . GCU H 3 .   ? 258.097 233.850 263.641 1.00 55.06  ? 2   GCU H C6  1 
HETATM 17244 O  O2  . GCU H 3 .   ? 255.282 234.003 258.807 1.00 53.12  ? 2   GCU H O2  1 
HETATM 17245 O  O3  . GCU H 3 .   ? 257.430 232.176 258.958 1.00 56.68  ? 2   GCU H O3  1 
HETATM 17246 O  O4  . GCU H 3 .   ? 258.774 231.905 261.487 1.00 58.57  ? 2   GCU H O4  1 
HETATM 17247 O  O5  . GCU H 3 .   ? 256.835 234.982 261.918 1.00 57.97  ? 2   GCU H O5  1 
HETATM 17248 O  O6A . GCU H 3 .   ? 257.668 233.147 264.594 1.00 56.79  ? 2   GCU H O6A 1 
HETATM 17249 O  O6B . GCU H 3 .   ? 259.065 234.608 263.660 1.00 52.88  ? 2   GCU H O6B 1 
HETATM 17250 H  H1  . GCU H 3 .   ? 255.667 235.864 260.677 1.00 49.85  ? 2   GCU H H1  1 
HETATM 17251 H  H2  . GCU H 3 .   ? 257.061 234.656 259.323 1.00 51.62  ? 2   GCU H H2  1 
HETATM 17252 H  H3  . GCU H 3 .   ? 256.236 232.241 260.526 1.00 52.90  ? 2   GCU H H3  1 
HETATM 17253 H  H4  . GCU H 3 .   ? 258.585 233.734 260.798 1.00 53.09  ? 2   GCU H H4  1 
HETATM 17254 H  H5  . GCU H 3 .   ? 256.505 233.149 262.572 1.00 53.31  ? 2   GCU H H5  1 
HETATM 17255 H  HO2 . GCU H 3 .   ? 254.663 233.571 259.198 1.00 52.98  ? 2   GCU H HO2 1 
HETATM 17256 H  HO3 . GCU H 3 .   ? 258.101 232.622 258.690 1.00 54.19  ? 2   GCU H HO3 1 
HETATM 17257 C  C1  . GLC H 3 .   ? 258.018 230.764 261.954 1.00 61.59  ? 3   GLC H C1  1 
HETATM 17258 C  C2  . GLC H 3 .   ? 258.750 230.150 263.164 1.00 65.92  ? 3   GLC H C2  1 
HETATM 17259 C  C3  . GLC H 3 .   ? 259.993 229.351 262.775 1.00 66.04  ? 3   GLC H C3  1 
HETATM 17260 C  C4  . GLC H 3 .   ? 259.655 228.314 261.715 1.00 66.05  ? 3   GLC H C4  1 
HETATM 17261 C  C5  . GLC H 3 .   ? 259.054 229.082 260.538 1.00 62.77  ? 3   GLC H C5  1 
HETATM 17262 C  C6  . GLC H 3 .   ? 258.638 228.170 259.396 1.00 64.73  ? 3   GLC H C6  1 
HETATM 17263 O  O2  . GLC H 3 .   ? 259.081 231.177 264.058 1.00 60.49  ? 3   GLC H O2  1 
HETATM 17264 O  O3  . GLC H 3 .   ? 260.596 228.777 263.912 1.00 67.73  ? 3   GLC H O3  1 
HETATM 17265 O  O4  . GLC H 3 .   ? 260.804 227.610 261.307 1.00 69.89  ? 3   GLC H O4  1 
HETATM 17266 O  O5  . GLC H 3 .   ? 257.888 229.773 260.957 1.00 67.27  ? 3   GLC H O5  1 
HETATM 17267 O  O6  . GLC H 3 .   ? 259.713 227.445 258.853 1.00 72.33  ? 3   GLC H O6  1 
HETATM 17268 H  H1  . GLC H 3 .   ? 257.115 231.014 262.199 1.00 59.70  ? 3   GLC H H1  1 
HETATM 17269 H  H2  . GLC H 3 .   ? 258.123 229.529 263.566 1.00 64.17  ? 3   GLC H H2  1 
HETATM 17270 H  H3  . GLC H 3 .   ? 260.666 229.945 262.408 1.00 61.81  ? 3   GLC H H3  1 
HETATM 17271 H  H4  . GLC H 3 .   ? 258.979 227.715 262.067 1.00 66.17  ? 3   GLC H H4  1 
HETATM 17272 H  H5  . GLC H 3 .   ? 259.723 229.703 260.212 1.00 60.93  ? 3   GLC H H5  1 
HETATM 17273 H  H61 . GLC H 3 .   ? 258.189 228.702 258.721 1.00 62.78  ? 3   GLC H H61 1 
HETATM 17274 H  H62 . GLC H 3 .   ? 257.995 227.523 259.725 1.00 64.97  ? 3   GLC H H62 1 
HETATM 17275 H  HO2 . GLC H 3 .   ? 259.627 231.698 263.668 1.00 58.90  ? 3   GLC H HO2 1 
HETATM 17276 H  HO3 . GLC H 3 .   ? 260.053 228.223 264.260 1.00 65.99  ? 3   GLC H HO3 1 
HETATM 17277 H  HO6 . GLC H 3 .   ? 259.432 227.029 258.167 1.00 69.48  ? 3   GLC H HO6 1 
HETATM 17278 C  C1  . FUC H 3 .   ? 260.561 226.177 261.306 1.00 77.29  ? 4   FUC H C1  1 
HETATM 17279 C  C2  . FUC H 3 .   ? 261.826 225.477 260.779 1.00 78.80  ? 4   FUC H C2  1 
HETATM 17280 C  C3  . FUC H 3 .   ? 262.973 225.612 261.776 1.00 77.80  ? 4   FUC H C3  1 
HETATM 17281 C  C4  . FUC H 3 .   ? 262.557 225.007 263.115 1.00 79.98  ? 4   FUC H C4  1 
HETATM 17282 C  C5  . FUC H 3 .   ? 261.289 225.722 263.582 1.00 80.27  ? 4   FUC H C5  1 
HETATM 17283 C  C6  . FUC H 3 .   ? 260.705 225.116 264.841 1.00 76.44  ? 4   FUC H C6  1 
HETATM 17284 O  O2  . FUC H 3 .   ? 262.136 226.021 259.523 1.00 77.12  ? 4   FUC H O2  1 
HETATM 17285 O  O3  . FUC H 3 .   ? 264.106 224.991 261.219 1.00 78.11  ? 4   FUC H O3  1 
HETATM 17286 O  O4  . FUC H 3 .   ? 262.379 223.622 262.947 1.00 80.83  ? 4   FUC H O4  1 
HETATM 17287 O  O5  . FUC H 3 .   ? 260.263 225.684 262.595 1.00 80.01  ? 4   FUC H O5  1 
HETATM 17288 H  H1  . FUC H 3 .   ? 259.793 225.956 260.756 1.00 74.42  ? 4   FUC H H1  1 
HETATM 17289 H  H2  . FUC H 3 .   ? 261.605 224.536 260.697 1.00 77.60  ? 4   FUC H H2  1 
HETATM 17290 H  H3  . FUC H 3 .   ? 263.143 226.555 261.929 1.00 76.76  ? 4   FUC H H3  1 
HETATM 17291 H  H4  . FUC H 3 .   ? 263.252 225.191 263.766 1.00 78.52  ? 4   FUC H H4  1 
HETATM 17292 H  H5  . FUC H 3 .   ? 261.539 226.638 263.773 1.00 76.77  ? 4   FUC H H5  1 
HETATM 17293 H  H61 . FUC H 3 .   ? 260.412 224.205 264.678 1.00 77.36  ? 4   FUC H H61 1 
HETATM 17294 H  H62 . FUC H 3 .   ? 259.943 225.619 265.165 1.00 76.12  ? 4   FUC H H62 1 
HETATM 17295 H  H63 . FUC H 3 .   ? 261.374 225.088 265.542 1.00 76.64  ? 4   FUC H H63 1 
HETATM 17296 H  HO2 . FUC H 3 .   ? 262.342 226.838 259.639 1.00 73.94  ? 4   FUC H HO2 1 
HETATM 17297 H  HO3 . FUC H 3 .   ? 264.011 224.148 261.279 1.00 78.67  ? 4   FUC H HO3 1 
HETATM 17298 H  HO4 . FUC H 3 .   ? 261.633 223.485 262.564 1.00 79.57  ? 4   FUC H HO4 1 
HETATM 17299 C  C1  . RAM H 3 .   ? 250.674 232.337 263.352 1.00 56.82  ? 5   RAM H C1  1 
HETATM 17300 C  C2  . RAM H 3 .   ? 250.064 231.151 262.496 1.00 53.98  ? 5   RAM H C2  1 
HETATM 17301 C  C3  . RAM H 3 .   ? 248.550 231.076 262.652 1.00 56.45  ? 5   RAM H C3  1 
HETATM 17302 C  C4  . RAM H 3 .   ? 248.144 230.966 264.142 1.00 59.43  ? 5   RAM H C4  1 
HETATM 17303 C  C5  . RAM H 3 .   ? 249.280 231.339 265.119 1.00 58.62  ? 5   RAM H C5  1 
HETATM 17304 C  C6  . RAM H 3 .   ? 248.782 231.674 266.508 1.00 58.33  ? 5   RAM H C6  1 
HETATM 17305 O  O2  . RAM H 3 .   ? 250.485 231.337 261.172 1.00 53.26  ? 5   RAM H O2  1 
HETATM 17306 O  O3  . RAM H 3 .   ? 248.000 232.201 262.016 1.00 57.26  ? 5   RAM H O3  1 
HETATM 17307 O  O4  . RAM H 3 .   ? 247.743 229.634 264.362 1.00 63.84  ? 5   RAM H O4  1 
HETATM 17308 O  O5  . RAM H 3 .   ? 249.990 232.475 264.638 1.00 59.57  ? 5   RAM H O5  1 
HETATM 17309 H  H1  . RAM H 3 .   ? 250.867 231.565 263.892 1.00 56.02  ? 5   RAM H H1  1 
HETATM 17310 H  H2  . RAM H 3 .   ? 250.415 230.314 262.840 1.00 54.83  ? 5   RAM H H2  1 
HETATM 17311 H  H3  . RAM H 3 .   ? 248.242 230.265 262.219 1.00 57.33  ? 5   RAM H H3  1 
HETATM 17312 H  H4  . RAM H 3 .   ? 247.401 231.571 264.289 1.00 57.61  ? 5   RAM H H4  1 
HETATM 17313 H  H5  . RAM H 3 .   ? 249.850 230.557 265.211 1.00 58.04  ? 5   RAM H H5  1 
HETATM 17314 H  H61 . RAM H 3 .   ? 249.520 231.876 267.105 1.00 57.17  ? 5   RAM H H61 1 
HETATM 17315 H  H62 . RAM H 3 .   ? 248.276 230.936 266.882 1.00 57.94  ? 5   RAM H H62 1 
HETATM 17316 H  H63 . RAM H 3 .   ? 248.203 232.451 266.486 1.00 57.13  ? 5   RAM H H63 1 
HETATM 17317 H  HO2 . RAM H 3 .   ? 250.066 232.002 260.849 1.00 54.68  ? 5   RAM H HO2 1 
HETATM 17318 H  HO3 . RAM H 3 .   ? 248.469 232.878 262.220 1.00 55.76  ? 5   RAM H HO3 1 
HETATM 17319 H  HO4 . RAM H 3 .   ? 247.049 229.472 263.899 1.00 61.16  ? 5   RAM H HO4 1 
HETATM 17320 C  C1  . MAN I 3 .   ? 292.413 226.268 247.801 1.00 34.91  ? 1   MAN I C1  1 
HETATM 17321 C  C2  . MAN I 3 .   ? 292.972 224.994 248.420 1.00 35.98  ? 1   MAN I C2  1 
HETATM 17322 C  C3  . MAN I 3 .   ? 292.077 224.611 249.599 1.00 37.08  ? 1   MAN I C3  1 
HETATM 17323 C  C4  . MAN I 3 .   ? 291.990 225.751 250.609 1.00 37.34  ? 1   MAN I C4  1 
HETATM 17324 C  C5  . MAN I 3 .   ? 291.676 227.083 249.920 1.00 35.29  ? 1   MAN I C5  1 
HETATM 17325 C  C6  . MAN I 3 .   ? 291.964 228.234 250.856 1.00 32.99  ? 1   MAN I C6  1 
HETATM 17326 O  O2  . MAN I 3 .   ? 294.291 225.332 248.786 1.00 45.47  ? 1   MAN I O2  1 
HETATM 17327 O  O3  . MAN I 3 .   ? 292.577 223.433 250.182 1.00 39.02  ? 1   MAN I O3  1 
HETATM 17328 O  O4  . MAN I 3 .   ? 290.935 225.421 251.488 1.00 40.13  ? 1   MAN I O4  1 
HETATM 17329 O  O5  . MAN I 3 .   ? 292.463 227.284 248.758 1.00 41.73  ? 1   MAN I O5  1 
HETATM 17330 O  O6  . MAN I 3 .   ? 291.302 229.379 250.386 1.00 36.94  ? 1   MAN I O6  1 
HETATM 17331 H  H1  . MAN I 3 .   ? 293.003 226.569 247.093 1.00 35.51  ? 1   MAN I H1  1 
HETATM 17332 H  H2  . MAN I 3 .   ? 292.956 224.289 247.754 1.00 37.90  ? 1   MAN I H2  1 
HETATM 17333 H  H3  . MAN I 3 .   ? 291.182 224.454 249.263 1.00 37.58  ? 1   MAN I H3  1 
HETATM 17334 H  H4  . MAN I 3 .   ? 292.839 225.825 251.070 1.00 37.97  ? 1   MAN I H4  1 
HETATM 17335 H  H5  . MAN I 3 .   ? 290.732 227.094 249.698 1.00 34.71  ? 1   MAN I H5  1 
HETATM 17336 H  H61 . MAN I 3 .   ? 292.924 228.367 250.895 1.00 31.55  ? 1   MAN I H61 1 
HETATM 17337 H  H62 . MAN I 3 .   ? 291.674 227.991 251.748 1.00 33.22  ? 1   MAN I H62 1 
HETATM 17338 H  HO3 . MAN I 3 .   ? 292.118 223.265 250.878 1.00 40.24  ? 1   MAN I HO3 1 
HETATM 17339 H  HO6 . MAN I 3 .   ? 291.605 229.563 249.614 1.00 32.06  ? 1   MAN I HO6 1 
HETATM 17340 C  C1  . GCU I 3 .   ? 295.155 224.184 248.991 1.00 45.97  ? 2   GCU I C1  1 
HETATM 17341 C  C2  . GCU I 3 .   ? 296.505 224.715 249.495 1.00 46.73  ? 2   GCU I C2  1 
HETATM 17342 C  C3  . GCU I 3 .   ? 297.288 225.447 248.411 1.00 50.94  ? 2   GCU I C3  1 
HETATM 17343 C  C4  . GCU I 3 .   ? 297.480 224.503 247.231 1.00 57.58  ? 2   GCU I C4  1 
HETATM 17344 C  C5  . GCU I 3 .   ? 296.078 224.077 246.774 1.00 53.82  ? 2   GCU I C5  1 
HETATM 17345 C  C6  . GCU I 3 .   ? 296.157 223.129 245.565 1.00 59.35  ? 2   GCU I C6  1 
HETATM 17346 O  O2  . GCU I 3 .   ? 296.256 225.522 250.614 1.00 49.21  ? 2   GCU I O2  1 
HETATM 17347 O  O3  . GCU I 3 .   ? 298.485 225.854 249.036 1.00 53.25  ? 2   GCU I O3  1 
HETATM 17348 O  O4  . GCU I 3 .   ? 298.155 225.074 246.135 1.00 60.17  ? 2   GCU I O4  1 
HETATM 17349 O  O5  . GCU I 3 .   ? 295.369 223.439 247.814 1.00 52.74  ? 2   GCU I O5  1 
HETATM 17350 O  O6A . GCU I 3 .   ? 296.522 223.682 244.493 1.00 60.36  ? 2   GCU I O6A 1 
HETATM 17351 O  O6B . GCU I 3 .   ? 295.870 221.945 245.729 1.00 63.45  ? 2   GCU I O6B 1 
HETATM 17352 H  H1  . GCU I 3 .   ? 294.777 223.564 249.631 1.00 45.53  ? 2   GCU I H1  1 
HETATM 17353 H  H2  . GCU I 3 .   ? 297.022 223.934 249.747 1.00 48.64  ? 2   GCU I H2  1 
HETATM 17354 H  H3  . GCU I 3 .   ? 296.779 226.216 248.110 1.00 51.23  ? 2   GCU I H3  1 
HETATM 17355 H  H4  . GCU I 3 .   ? 297.942 223.715 247.557 1.00 55.95  ? 2   GCU I H4  1 
HETATM 17356 H  H5  . GCU I 3 .   ? 295.610 224.874 246.478 1.00 50.65  ? 2   GCU I H5  1 
HETATM 17357 H  HO2 . GCU I 3 .   ? 295.765 226.168 250.360 1.00 45.95  ? 2   GCU I HO2 1 
HETATM 17358 H  HO3 . GCU I 3 .   ? 298.938 225.161 249.225 1.00 52.10  ? 2   GCU I HO3 1 
HETATM 17359 C  C1  . GLC I 3 .   ? 299.463 225.611 246.470 1.00 66.89  ? 3   GLC I C1  1 
HETATM 17360 C  C2  . GLC I 3 .   ? 300.190 225.920 245.137 1.00 67.80  ? 3   GLC I C2  1 
HETATM 17361 C  C3  . GLC I 3 .   ? 301.021 224.771 244.573 1.00 68.34  ? 3   GLC I C3  1 
HETATM 17362 C  C4  . GLC I 3 .   ? 301.914 224.193 245.658 1.00 70.02  ? 3   GLC I C4  1 
HETATM 17363 C  C5  . GLC I 3 .   ? 300.955 223.643 246.711 1.00 69.82  ? 3   GLC I C5  1 
HETATM 17364 C  C6  . GLC I 3 .   ? 301.664 222.947 247.864 1.00 70.83  ? 3   GLC I C6  1 
HETATM 17365 O  O2  . GLC I 3 .   ? 299.221 226.335 244.213 1.00 66.34  ? 3   GLC I O2  1 
HETATM 17366 O  O3  . GLC I 3 .   ? 301.742 225.192 243.437 1.00 69.78  ? 3   GLC I O3  1 
HETATM 17367 O  O4  . GLC I 3 .   ? 302.752 223.171 245.170 1.00 73.77  ? 3   GLC I O4  1 
HETATM 17368 O  O5  . GLC I 3 .   ? 300.222 224.717 247.278 1.00 71.85  ? 3   GLC I O5  1 
HETATM 17369 O  O6  . GLC I 3 .   ? 302.626 222.006 247.455 1.00 77.55  ? 3   GLC I O6  1 
HETATM 17370 H  H1  . GLC I 3 .   ? 299.374 226.428 246.985 1.00 64.24  ? 3   GLC I H1  1 
HETATM 17371 H  H2  . GLC I 3 .   ? 300.805 226.643 245.339 1.00 67.02  ? 3   GLC I H2  1 
HETATM 17372 H  H3  . GLC I 3 .   ? 300.437 224.065 244.253 1.00 67.81  ? 3   GLC I H3  1 
HETATM 17373 H  H4  . GLC I 3 .   ? 302.426 224.914 246.055 1.00 69.80  ? 3   GLC I H4  1 
HETATM 17374 H  H5  . GLC I 3 .   ? 300.361 223.009 246.280 1.00 67.48  ? 3   GLC I H5  1 
HETATM 17375 H  H61 . GLC I 3 .   ? 300.996 222.540 248.437 1.00 69.48  ? 3   GLC I H61 1 
HETATM 17376 H  H62 . GLC I 3 .   ? 302.129 223.612 248.395 1.00 69.86  ? 3   GLC I H62 1 
HETATM 17377 H  HO2 . GLC I 3 .   ? 298.752 225.657 244.004 1.00 65.41  ? 3   GLC I HO2 1 
HETATM 17378 H  HO3 . GLC I 3 .   ? 302.300 225.788 243.674 1.00 68.65  ? 3   GLC I HO3 1 
HETATM 17379 H  HO6 . GLC I 3 .   ? 302.266 221.486 246.888 1.00 76.22  ? 3   GLC I HO6 1 
HETATM 17380 C  C1  . FUC I 3 .   ? 304.137 223.477 245.484 1.00 76.82  ? 4   FUC I C1  1 
HETATM 17381 C  C2  . FUC I 3 .   ? 305.012 222.264 245.119 1.00 77.86  ? 4   FUC I C2  1 
HETATM 17382 C  C3  . FUC I 3 .   ? 305.062 222.063 243.607 1.00 77.34  ? 4   FUC I C3  1 
HETATM 17383 C  C4  . FUC I 3 .   ? 305.605 223.326 242.943 1.00 74.28  ? 4   FUC I C4  1 
HETATM 17384 C  C5  . FUC I 3 .   ? 304.709 224.494 243.352 1.00 74.64  ? 4   FUC I C5  1 
HETATM 17385 C  C6  . FUC I 3 .   ? 305.218 225.828 242.848 1.00 71.04  ? 4   FUC I C6  1 
HETATM 17386 O  O2  . FUC I 3 .   ? 304.513 221.140 245.794 1.00 75.59  ? 4   FUC I O2  1 
HETATM 17387 O  O3  . FUC I 3 .   ? 305.845 220.922 243.356 1.00 78.66  ? 4   FUC I O3  1 
HETATM 17388 O  O4  . FUC I 3 .   ? 306.947 223.503 243.327 1.00 76.61  ? 4   FUC I O4  1 
HETATM 17389 O  O5  . FUC I 3 .   ? 304.601 224.603 244.769 1.00 77.72  ? 4   FUC I O5  1 
HETATM 17390 H  H1  . FUC I 3 .   ? 304.237 223.699 246.423 1.00 75.00  ? 4   FUC I H1  1 
HETATM 17391 H  H2  . FUC I 3 .   ? 305.908 222.473 245.425 1.00 76.80  ? 4   FUC I H2  1 
HETATM 17392 H  H3  . FUC I 3 .   ? 304.158 221.934 243.282 1.00 76.10  ? 4   FUC I H3  1 
HETATM 17393 H  H4  . FUC I 3 .   ? 305.530 223.227 241.981 1.00 74.72  ? 4   FUC I H4  1 
HETATM 17394 H  H5  . FUC I 3 .   ? 303.840 224.331 242.957 1.00 74.13  ? 4   FUC I H5  1 
HETATM 17395 H  H61 . FUC I 3 .   ? 306.078 226.038 243.243 1.00 72.51  ? 4   FUC I H61 1 
HETATM 17396 H  H62 . FUC I 3 .   ? 304.609 226.553 243.062 1.00 71.18  ? 4   FUC I H62 1 
HETATM 17397 H  H63 . FUC I 3 .   ? 305.335 225.802 241.886 1.00 72.00  ? 4   FUC I H63 1 
HETATM 17398 H  HO2 . FUC I 3 .   ? 303.738 220.977 245.487 1.00 76.26  ? 4   FUC I HO2 1 
HETATM 17399 H  HO3 . FUC I 3 .   ? 305.562 220.285 243.844 1.00 77.86  ? 4   FUC I HO3 1 
HETATM 17400 H  HO4 . FUC I 3 .   ? 306.969 223.823 244.114 1.00 76.01  ? 4   FUC I HO4 1 
HETATM 17401 C  C1  . RAM I 3 .   ? 291.333 225.423 252.875 1.00 38.56  ? 5   RAM I C1  1 
HETATM 17402 C  C2  . RAM I 3 .   ? 290.124 225.882 253.700 1.00 41.34  ? 5   RAM I C2  1 
HETATM 17403 C  C3  . RAM I 3 .   ? 289.839 224.935 254.859 1.00 47.85  ? 5   RAM I C3  1 
HETATM 17404 C  C4  . RAM I 3 .   ? 289.674 223.493 254.341 1.00 45.48  ? 5   RAM I C4  1 
HETATM 17405 C  C5  . RAM I 3 .   ? 290.683 223.188 253.219 1.00 43.11  ? 5   RAM I C5  1 
HETATM 17406 C  C6  . RAM I 3 .   ? 291.298 221.813 253.342 1.00 43.01  ? 5   RAM I C6  1 
HETATM 17407 O  O2  . RAM I 3 .   ? 290.389 227.194 254.126 1.00 39.18  ? 5   RAM I O2  1 
HETATM 17408 O  O3  . RAM I 3 .   ? 290.887 225.061 255.788 1.00 54.24  ? 5   RAM I O3  1 
HETATM 17409 O  O4  . RAM I 3 .   ? 288.349 223.354 253.884 1.00 46.70  ? 5   RAM I O4  1 
HETATM 17410 O  O5  . RAM I 3 .   ? 291.730 224.137 253.264 1.00 43.69  ? 5   RAM I O5  1 
HETATM 17411 H  H1  . RAM I 3 .   ? 292.094 226.003 253.031 1.00 38.27  ? 5   RAM I H1  1 
HETATM 17412 H  H2  . RAM I 3 .   ? 289.342 225.862 253.126 1.00 39.89  ? 5   RAM I H2  1 
HETATM 17413 H  H3  . RAM I 3 .   ? 288.994 225.191 255.262 1.00 45.61  ? 5   RAM I H3  1 
HETATM 17414 H  H4  . RAM I 3 .   ? 289.846 222.890 255.081 1.00 46.15  ? 5   RAM I H4  1 
HETATM 17415 H  H5  . RAM I 3 .   ? 290.212 223.243 252.373 1.00 43.14  ? 5   RAM I H5  1 
HETATM 17416 H  H61 . RAM I 3 .   ? 291.916 221.636 252.615 1.00 43.74  ? 5   RAM I H61 1 
HETATM 17417 H  H62 . RAM I 3 .   ? 290.614 221.126 253.342 1.00 44.50  ? 5   RAM I H62 1 
HETATM 17418 H  H63 . RAM I 3 .   ? 291.793 221.738 254.172 1.00 44.44  ? 5   RAM I H63 1 
HETATM 17419 H  HO2 . RAM I 3 .   ? 290.587 227.664 253.447 1.00 37.17  ? 5   RAM I HO2 1 
HETATM 17420 H  HO3 . RAM I 3 .   ? 290.884 225.857 256.087 1.00 48.92  ? 5   RAM I HO3 1 
HETATM 17421 H  HO4 . RAM I 3 .   ? 288.230 223.871 253.220 1.00 43.34  ? 5   RAM I HO4 1 
HETATM 17422 C  C1  . MAN J 3 .   ? 301.144 225.975 263.007 1.00 50.67  ? 1   MAN J C1  1 
HETATM 17423 C  C2  . MAN J 3 .   ? 301.052 225.132 261.727 1.00 51.43  ? 1   MAN J C2  1 
HETATM 17424 C  C3  . MAN J 3 .   ? 300.062 223.998 261.948 1.00 54.90  ? 1   MAN J C3  1 
HETATM 17425 C  C4  . MAN J 3 .   ? 300.676 223.177 263.076 1.00 57.73  ? 1   MAN J C4  1 
HETATM 17426 C  C5  . MAN J 3 .   ? 300.524 224.036 264.331 1.00 55.14  ? 1   MAN J C5  1 
HETATM 17427 C  C6  . MAN J 3 .   ? 301.004 223.315 265.568 1.00 57.37  ? 1   MAN J C6  1 
HETATM 17428 O  O2  . MAN J 3 .   ? 302.292 224.520 261.450 1.00 57.69  ? 1   MAN J O2  1 
HETATM 17429 O  O3  . MAN J 3 .   ? 299.910 223.287 260.744 1.00 56.64  ? 1   MAN J O3  1 
HETATM 17430 O  O4  . MAN J 3 .   ? 300.144 221.865 263.150 1.00 59.85  ? 1   MAN J O4  1 
HETATM 17431 O  O5  . MAN J 3 .   ? 301.323 225.202 264.169 1.00 55.48  ? 1   MAN J O5  1 
HETATM 17432 O  O6  . MAN J 3 .   ? 300.882 224.179 266.671 1.00 59.20  ? 1   MAN J O6  1 
HETATM 17433 H  H1  . MAN J 3 .   ? 301.922 226.552 262.968 1.00 47.82  ? 1   MAN J H1  1 
HETATM 17434 H  H2  . MAN J 3 .   ? 300.754 225.694 260.995 1.00 49.25  ? 1   MAN J H2  1 
HETATM 17435 H  H3  . MAN J 3 .   ? 299.220 224.371 262.251 1.00 52.77  ? 1   MAN J H3  1 
HETATM 17436 H  H4  . MAN J 3 .   ? 301.625 223.090 262.912 1.00 57.24  ? 1   MAN J H4  1 
HETATM 17437 H  H5  . MAN J 3 .   ? 299.588 224.268 264.443 1.00 53.89  ? 1   MAN J H5  1 
HETATM 17438 H  H61 . MAN J 3 .   ? 301.926 223.045 265.429 1.00 55.77  ? 1   MAN J H61 1 
HETATM 17439 H  H62 . MAN J 3 .   ? 300.482 222.505 265.678 1.00 57.14  ? 1   MAN J H62 1 
HETATM 17440 H  HO3 . MAN J 3 .   ? 300.680 223.170 260.408 1.00 56.06  ? 1   MAN J HO3 1 
HETATM 17441 H  HO6 . MAN J 3 .   ? 300.078 224.455 266.700 1.00 55.97  ? 1   MAN J HO6 1 
HETATM 17442 C  C1  . GCU J 3 .   ? 303.363 225.393 261.056 1.00 56.54  ? 2   GCU J C1  1 
HETATM 17443 C  C2  . GCU J 3 .   ? 304.120 224.702 259.912 1.00 57.70  ? 2   GCU J C2  1 
HETATM 17444 C  C3  . GCU J 3 .   ? 304.922 223.497 260.403 1.00 57.50  ? 2   GCU J C3  1 
HETATM 17445 C  C4  . GCU J 3 .   ? 305.846 223.999 261.503 1.00 60.29  ? 2   GCU J C4  1 
HETATM 17446 C  C5  . GCU J 3 .   ? 304.909 224.488 262.621 1.00 59.10  ? 2   GCU J C5  1 
HETATM 17447 C  C6  . GCU J 3 .   ? 305.630 224.825 263.939 1.00 59.29  ? 2   GCU J C6  1 
HETATM 17448 O  O2  . GCU J 3 .   ? 303.192 224.359 258.918 1.00 56.48  ? 2   GCU J O2  1 
HETATM 17449 O  O3  . GCU J 3 .   ? 305.607 222.963 259.293 1.00 60.81  ? 2   GCU J O3  1 
HETATM 17450 O  O4  . GCU J 3 .   ? 306.821 223.053 261.896 1.00 66.02  ? 2   GCU J O4  1 
HETATM 17451 O  O5  . GCU J 3 .   ? 304.223 225.629 262.142 1.00 64.89  ? 2   GCU J O5  1 
HETATM 17452 O  O6A . GCU J 3 .   ? 305.734 223.851 264.727 1.00 66.13  ? 2   GCU J O6A 1 
HETATM 17453 O  O6B . GCU J 3 .   ? 306.024 225.972 264.135 1.00 54.55  ? 2   GCU J O6B 1 
HETATM 17454 H  H1  . GCU J 3 .   ? 303.026 226.259 260.779 1.00 53.21  ? 2   GCU J H1  1 
HETATM 17455 H  H2  . GCU J 3 .   ? 304.751 225.356 259.575 1.00 56.04  ? 2   GCU J H2  1 
HETATM 17456 H  H3  . GCU J 3 .   ? 304.314 222.841 260.778 1.00 57.39  ? 2   GCU J H3  1 
HETATM 17457 H  H4  . GCU J 3 .   ? 306.287 224.786 261.148 1.00 57.20  ? 2   GCU J H4  1 
HETATM 17458 H  H5  . GCU J 3 .   ? 304.284 223.773 262.818 1.00 57.99  ? 2   GCU J H5  1 
HETATM 17459 H  HO2 . GCU J 3 .   ? 302.651 223.798 259.256 1.00 56.79  ? 2   GCU J HO2 1 
HETATM 17460 H  HO3 . GCU J 3 .   ? 306.210 223.514 259.060 1.00 58.67  ? 2   GCU J HO3 1 
HETATM 17461 C  C1  . GLC J 3 .   ? 306.312 221.736 262.205 1.00 68.92  ? 3   GLC J C1  1 
HETATM 17462 C  C2  . GLC J 3 .   ? 307.197 221.131 263.316 1.00 71.35  ? 3   GLC J C2  1 
HETATM 17463 C  C3  . GLC J 3 .   ? 308.544 220.630 262.804 1.00 70.84  ? 3   GLC J C3  1 
HETATM 17464 C  C4  . GLC J 3 .   ? 308.326 219.655 261.660 1.00 72.78  ? 3   GLC J C4  1 
HETATM 17465 C  C5  . GLC J 3 .   ? 307.580 220.437 260.581 1.00 70.68  ? 3   GLC J C5  1 
HETATM 17466 C  C6  . GLC J 3 .   ? 307.298 219.591 259.352 1.00 72.75  ? 3   GLC J C6  1 
HETATM 17467 O  O2  . GLC J 3 .   ? 307.376 222.091 264.320 1.00 66.11  ? 3   GLC J O2  1 
HETATM 17468 O  O3  . GLC J 3 .   ? 309.314 220.080 263.849 1.00 73.07  ? 3   GLC J O3  1 
HETATM 17469 O  O4  . GLC J 3 .   ? 309.538 219.152 261.148 1.00 78.19  ? 3   GLC J O4  1 
HETATM 17470 O  O5  . GLC J 3 .   ? 306.329 220.878 261.083 1.00 71.72  ? 3   GLC J O5  1 
HETATM 17471 O  O6  . GLC J 3 .   ? 308.466 219.075 258.766 1.00 78.82  ? 3   GLC J O6  1 
HETATM 17472 H  H1  . GLC J 3 .   ? 305.387 221.778 262.495 1.00 66.03  ? 3   GLC J H1  1 
HETATM 17473 H  H2  . GLC J 3 .   ? 306.712 220.362 263.653 1.00 70.25  ? 3   GLC J H2  1 
HETATM 17474 H  H3  . GLC J 3 .   ? 309.069 221.374 262.470 1.00 67.92  ? 3   GLC J H3  1 
HETATM 17475 H  H4  . GLC J 3 .   ? 307.750 218.939 261.970 1.00 72.24  ? 3   GLC J H4  1 
HETATM 17476 H  H5  . GLC J 3 .   ? 308.132 221.190 260.320 1.00 67.67  ? 3   GLC J H5  1 
HETATM 17477 H  H61 . GLC J 3 .   ? 306.784 220.119 258.721 1.00 70.17  ? 3   GLC J H61 1 
HETATM 17478 H  H62 . GLC J 3 .   ? 306.748 218.834 259.608 1.00 72.51  ? 3   GLC J H62 1 
HETATM 17479 H  HO2 . GLC J 3 .   ? 307.787 222.753 263.980 1.00 64.46  ? 3   GLC J HO2 1 
HETATM 17480 H  HO3 . GLC J 3 .   ? 308.911 219.398 264.157 1.00 71.80  ? 3   GLC J HO3 1 
HETATM 17481 H  HO6 . GLC J 3 .   ? 308.254 218.713 258.027 1.00 75.88  ? 3   GLC J HO6 1 
HETATM 17482 C  C1  . FUC J 3 .   ? 309.499 217.700 261.128 1.00 84.89  ? 4   FUC J C1  1 
HETATM 17483 C  C2  . FUC J 3 .   ? 310.733 217.175 260.374 1.00 87.00  ? 4   FUC J C2  1 
HETATM 17484 C  C3  . FUC J 3 .   ? 312.012 217.472 261.152 1.00 85.72  ? 4   FUC J C3  1 
HETATM 17485 C  C4  . FUC J 3 .   ? 311.924 216.853 262.545 1.00 85.72  ? 4   FUC J C4  1 
HETATM 17486 C  C5  . FUC J 3 .   ? 310.662 217.382 263.228 1.00 86.07  ? 4   FUC J C5  1 
HETATM 17487 C  C6  . FUC J 3 .   ? 310.404 216.734 264.573 1.00 85.39  ? 4   FUC J C6  1 
HETATM 17488 O  O2  . FUC J 3 .   ? 310.743 217.741 259.090 1.00 86.21  ? 4   FUC J O2  1 
HETATM 17489 O  O3  . FUC J 3 .   ? 313.091 216.977 260.395 1.00 86.58  ? 4   FUC J O3  1 
HETATM 17490 O  O4  . FUC J 3 .   ? 311.931 215.452 262.415 1.00 88.75  ? 4   FUC J O4  1 
HETATM 17491 O  O5  . FUC J 3 .   ? 309.501 217.161 262.432 1.00 86.07  ? 4   FUC J O5  1 
HETATM 17492 H  H1  . FUC J 3 .   ? 308.684 217.382 260.709 1.00 81.57  ? 4   FUC J H1  1 
HETATM 17493 H  H2  . FUC J 3 .   ? 310.631 216.212 260.320 1.00 85.19  ? 4   FUC J H2  1 
HETATM 17494 H  H3  . FUC J 3 .   ? 312.089 218.432 261.268 1.00 83.44  ? 4   FUC J H3  1 
HETATM 17495 H  H4  . FUC J 3 .   ? 312.684 217.157 263.065 1.00 85.30  ? 4   FUC J H4  1 
HETATM 17496 H  H5  . FUC J 3 .   ? 310.797 218.331 263.369 1.00 83.26  ? 4   FUC J H5  1 
HETATM 17497 H  H61 . FUC J 3 .   ? 310.235 215.785 264.471 1.00 85.07  ? 4   FUC J H61 1 
HETATM 17498 H  H62 . FUC J 3 .   ? 309.638 217.125 265.021 1.00 84.37  ? 4   FUC J H62 1 
HETATM 17499 H  H63 . FUC J 3 .   ? 311.178 216.835 265.149 1.00 84.67  ? 4   FUC J H63 1 
HETATM 17500 H  HO2 . FUC J 3 .   ? 310.868 218.577 259.177 1.00 82.51  ? 4   FUC J HO2 1 
HETATM 17501 H  HO3 . FUC J 3 .   ? 313.123 216.133 260.488 1.00 86.46  ? 4   FUC J HO3 1 
HETATM 17502 H  HO4 . FUC J 3 .   ? 311.163 215.195 262.157 1.00 87.26  ? 4   FUC J HO4 1 
HETATM 17503 C  C1  . RAM J 3 .   ? 298.659 221.732 263.132 1.00 60.71  ? 5   RAM J C1  1 
HETATM 17504 C  C2  . RAM J 3 .   ? 298.268 220.386 262.393 1.00 59.53  ? 5   RAM J C2  1 
HETATM 17505 C  C3  . RAM J 3 .   ? 296.796 220.056 262.597 1.00 62.15  ? 5   RAM J C3  1 
HETATM 17506 C  C4  . RAM J 3 .   ? 296.450 219.979 264.102 1.00 62.95  ? 5   RAM J C4  1 
HETATM 17507 C  C5  . RAM J 3 .   ? 297.513 220.629 265.014 1.00 63.44  ? 5   RAM J C5  1 
HETATM 17508 C  C6  . RAM J 3 .   ? 296.979 220.970 266.389 1.00 62.07  ? 5   RAM J C6  1 
HETATM 17509 O  O2  . RAM J 3 .   ? 298.632 220.526 261.046 1.00 58.19  ? 5   RAM J O2  1 
HETATM 17510 O  O3  . RAM J 3 .   ? 296.040 221.018 261.908 1.00 62.97  ? 5   RAM J O3  1 
HETATM 17511 O  O4  . RAM J 3 .   ? 296.310 218.612 264.416 1.00 68.45  ? 5   RAM J O4  1 
HETATM 17512 O  O5  . RAM J 3 .   ? 297.996 221.835 264.431 1.00 65.64  ? 5   RAM J O5  1 
HETATM 17513 H  H1  . RAM J 3 .   ? 299.015 221.067 263.731 1.00 60.42  ? 5   RAM J H1  1 
HETATM 17514 H  H2  . RAM J 3 .   ? 298.767 219.660 262.797 1.00 60.06  ? 5   RAM J H2  1 
HETATM 17515 H  H3  . RAM J 3 .   ? 296.631 219.173 262.227 1.00 62.86  ? 5   RAM J H3  1 
HETATM 17516 H  H4  . RAM J 3 .   ? 295.608 220.443 264.232 1.00 61.57  ? 5   RAM J H4  1 
HETATM 17517 H  H5  . RAM J 3 .   ? 298.220 219.975 265.144 1.00 62.66  ? 5   RAM J H5  1 
HETATM 17518 H  H61 . RAM J 3 .   ? 297.674 221.349 266.951 1.00 60.35  ? 5   RAM J H61 1 
HETATM 17519 H  H62 . RAM J 3 .   ? 296.627 220.180 266.828 1.00 61.79  ? 5   RAM J H62 1 
HETATM 17520 H  H63 . RAM J 3 .   ? 296.264 221.621 266.328 1.00 61.00  ? 5   RAM J H63 1 
HETATM 17521 H  HO2 . RAM J 3 .   ? 298.078 221.052 260.672 1.00 59.46  ? 5   RAM J HO2 1 
HETATM 17522 H  HO3 . RAM J 3 .   ? 296.294 221.787 262.161 1.00 60.56  ? 5   RAM J HO3 1 
HETATM 17523 H  HO4 . RAM J 3 .   ? 295.653 218.293 263.982 1.00 65.80  ? 5   RAM J HO4 1 
HETATM 17524 C  C1  . MAN K 3 .   ? 201.243 258.201 247.858 1.00 39.50  ? 1   MAN K C1  1 
HETATM 17525 C  C2  . MAN K 3 .   ? 201.273 256.849 248.558 1.00 39.21  ? 1   MAN K C2  1 
HETATM 17526 C  C3  . MAN K 3 .   ? 200.296 256.884 249.730 1.00 40.26  ? 1   MAN K C3  1 
HETATM 17527 C  C4  . MAN K 3 .   ? 200.626 258.035 250.672 1.00 40.37  ? 1   MAN K C4  1 
HETATM 17528 C  C5  . MAN K 3 .   ? 200.805 259.346 249.900 1.00 37.97  ? 1   MAN K C5  1 
HETATM 17529 C  C6  . MAN K 3 .   ? 201.457 260.390 250.776 1.00 34.50  ? 1   MAN K C6  1 
HETATM 17530 O  O2  . MAN K 3 .   ? 202.609 256.684 248.967 1.00 48.31  ? 1   MAN K O2  1 
HETATM 17531 O  O3  . MAN K 3 .   ? 200.353 255.644 250.391 1.00 42.19  ? 1   MAN K O3  1 
HETATM 17532 O  O4  . MAN K 3 .   ? 199.527 258.145 251.550 1.00 40.82  ? 1   MAN K O4  1 
HETATM 17533 O  O5  . MAN K 3 .   ? 201.637 259.187 248.764 1.00 44.67  ? 1   MAN K O5  1 
HETATM 17534 O  O6  . MAN K 3 .   ? 201.367 261.634 250.130 1.00 40.11  ? 1   MAN K O6  1 
HETATM 17535 H  H1  . MAN K 3 .   ? 201.921 258.219 247.165 1.00 39.09  ? 1   MAN K H1  1 
HETATM 17536 H  H2  . MAN K 3 .   ? 201.003 256.163 247.928 1.00 41.08  ? 1   MAN K H2  1 
HETATM 17537 H  H3  . MAN K 3 .   ? 199.402 257.036 249.385 1.00 40.70  ? 1   MAN K H3  1 
HETATM 17538 H  H4  . MAN K 3 .   ? 201.449 257.828 251.141 1.00 40.01  ? 1   MAN K H4  1 
HETATM 17539 H  H5  . MAN K 3 .   ? 199.928 259.666 249.638 1.00 37.11  ? 1   MAN K H5  1 
HETATM 17540 H  H61 . MAN K 3 .   ? 202.379 260.132 250.929 1.00 32.71  ? 1   MAN K H61 1 
HETATM 17541 H  H62 . MAN K 3 .   ? 201.014 260.396 251.638 1.00 34.27  ? 1   MAN K H62 1 
HETATM 17542 H  HO3 . MAN K 3 .   ? 199.889 255.702 251.102 1.00 43.60  ? 1   MAN K HO3 1 
HETATM 17543 H  HO6 . MAN K 3 .   ? 201.780 261.577 249.390 1.00 34.39  ? 1   MAN K HO6 1 
HETATM 17544 C  C1  . GCU K 3 .   ? 202.986 255.294 249.118 1.00 48.37  ? 2   GCU K C1  1 
HETATM 17545 C  C2  . GCU K 3 .   ? 204.423 255.276 249.658 1.00 49.84  ? 2   GCU K C2  1 
HETATM 17546 C  C3  . GCU K 3 .   ? 205.416 255.775 248.617 1.00 50.83  ? 2   GCU K C3  1 
HETATM 17547 C  C4  . GCU K 3 .   ? 205.263 254.923 247.370 1.00 54.69  ? 2   GCU K C4  1 
HETATM 17548 C  C5  . GCU K 3 .   ? 203.812 255.043 246.893 1.00 55.91  ? 2   GCU K C5  1 
HETATM 17549 C  C6  . GCU K 3 .   ? 203.597 254.236 245.600 1.00 59.02  ? 2   GCU K C6  1 
HETATM 17550 O  O2  . GCU K 3 .   ? 204.455 256.031 250.839 1.00 49.02  ? 2   GCU K O2  1 
HETATM 17551 O  O3  . GCU K 3 .   ? 206.698 255.681 249.194 1.00 53.28  ? 2   GCU K O3  1 
HETATM 17552 O  O4  . GCU K 3 .   ? 206.153 255.330 246.361 1.00 58.66  ? 2   GCU K O4  1 
HETATM 17553 O  O5  . GCU K 3 .   ? 202.932 254.593 247.899 1.00 56.73  ? 2   GCU K O5  1 
HETATM 17554 O  O6A . GCU K 3 .   ? 204.078 254.781 244.571 1.00 58.36  ? 2   GCU K O6A 1 
HETATM 17555 O  O6B . GCU K 3 .   ? 202.999 253.163 245.659 1.00 61.46  ? 2   GCU K O6B 1 
HETATM 17556 H  H1  . GCU K 3 .   ? 202.391 254.826 249.722 1.00 47.75  ? 2   GCU K H1  1 
HETATM 17557 H  H2  . GCU K 3 .   ? 204.630 254.346 249.840 1.00 51.09  ? 2   GCU K H2  1 
HETATM 17558 H  H3  . GCU K 3 .   ? 205.209 256.694 248.388 1.00 51.52  ? 2   GCU K H3  1 
HETATM 17559 H  H4  . GCU K 3 .   ? 205.402 254.002 247.633 1.00 54.43  ? 2   GCU K H4  1 
HETATM 17560 H  H5  . GCU K 3 .   ? 203.645 255.975 246.681 1.00 52.36  ? 2   GCU K H5  1 
HETATM 17561 H  HO2 . GCU K 3 .   ? 204.229 256.826 250.642 1.00 46.31  ? 2   GCU K HO2 1 
HETATM 17562 H  HO3 . GCU K 3 .   ? 206.880 254.858 249.310 1.00 52.46  ? 2   GCU K HO3 1 
HETATM 17563 C  C1  . GLC K 3 .   ? 207.421 254.628 246.454 1.00 65.52  ? 3   GLC K C1  1 
HETATM 17564 C  C2  . GLC K 3 .   ? 208.199 254.941 245.159 1.00 69.82  ? 3   GLC K C2  1 
HETATM 17565 C  C3  . GLC K 3 .   ? 208.658 253.693 244.421 1.00 71.70  ? 3   GLC K C3  1 
HETATM 17566 C  C4  . GLC K 3 .   ? 209.304 252.743 245.415 1.00 70.68  ? 3   GLC K C4  1 
HETATM 17567 C  C5  . GLC K 3 .   ? 208.215 252.252 246.367 1.00 71.10  ? 3   GLC K C5  1 
HETATM 17568 C  C6  . GLC K 3 .   ? 208.759 251.844 247.730 1.00 71.34  ? 3   GLC K C6  1 
HETATM 17569 O  O2  . GLC K 3 .   ? 207.390 255.755 244.354 1.00 70.41  ? 3   GLC K O2  1 
HETATM 17570 O  O3  . GLC K 3 .   ? 209.513 254.026 243.350 1.00 70.93  ? 3   GLC K O3  1 
HETATM 17571 O  O4  . GLC K 3 .   ? 209.847 251.622 244.764 1.00 77.74  ? 3   GLC K O4  1 
HETATM 17572 O  O5  . GLC K 3 .   ? 207.224 253.234 246.635 1.00 69.31  ? 3   GLC K O5  1 
HETATM 17573 O  O6  . GLC K 3 .   ? 209.748 250.847 247.680 1.00 76.68  ? 3   GLC K O6  1 
HETATM 17574 H  H1  . GLC K 3 .   ? 207.918 254.934 247.229 1.00 64.45  ? 3   GLC K H1  1 
HETATM 17575 H  H2  . GLC K 3 .   ? 208.996 255.415 245.440 1.00 66.87  ? 3   GLC K H2  1 
HETATM 17576 H  H3  . GLC K 3 .   ? 207.900 253.244 244.014 1.00 70.20  ? 3   GLC K H3  1 
HETATM 17577 H  H4  . GLC K 3 .   ? 209.972 253.226 245.925 1.00 70.01  ? 3   GLC K H4  1 
HETATM 17578 H  H5  . GLC K 3 .   ? 207.809 251.475 245.953 1.00 70.87  ? 3   GLC K H5  1 
HETATM 17579 H  H61 . GLC K 3 .   ? 208.014 251.575 248.289 1.00 70.04  ? 3   GLC K H61 1 
HETATM 17580 H  H62 . GLC K 3 .   ? 209.162 252.620 248.149 1.00 69.27  ? 3   GLC K H62 1 
HETATM 17581 H  HO2 . GLC K 3 .   ? 206.705 255.305 244.130 1.00 66.33  ? 3   GLC K HO2 1 
HETATM 17582 H  HO3 . GLC K 3 .   ? 210.204 254.412 243.662 1.00 69.75  ? 3   GLC K HO3 1 
HETATM 17583 H  HO6 . GLC K 3 .   ? 209.440 250.190 247.239 1.00 76.24  ? 3   GLC K HO6 1 
HETATM 17584 C  C1  . FUC K 3 .   ? 211.227 251.410 245.146 1.00 78.28  ? 4   FUC K C1  1 
HETATM 17585 C  C2  . FUC K 3 .   ? 211.626 250.000 244.691 1.00 76.72  ? 4   FUC K C2  1 
HETATM 17586 C  C3  . FUC K 3 .   ? 211.627 249.920 243.167 1.00 80.68  ? 4   FUC K C3  1 
HETATM 17587 C  C4  . FUC K 3 .   ? 212.581 250.969 242.601 1.00 80.73  ? 4   FUC K C4  1 
HETATM 17588 C  C5  . FUC K 3 .   ? 212.145 252.338 243.125 1.00 80.25  ? 4   FUC K C5  1 
HETATM 17589 C  C6  . FUC K 3 .   ? 213.080 253.456 242.717 1.00 78.66  ? 4   FUC K C6  1 
HETATM 17590 O  O2  . FUC K 3 .   ? 210.740 249.084 245.277 1.00 75.69  ? 4   FUC K O2  1 
HETATM 17591 O  O3  . FUC K 3 .   ? 211.972 248.605 242.805 1.00 84.47  ? 4   FUC K O3  1 
HETATM 17592 O  O4  . FUC K 3 .   ? 213.895 250.629 242.972 1.00 79.96  ? 4   FUC K O4  1 
HETATM 17593 O  O5  . FUC K 3 .   ? 212.084 252.351 244.546 1.00 79.37  ? 4   FUC K O5  1 
HETATM 17594 H  H1  . FUC K 3 .   ? 211.350 251.511 246.102 1.00 76.89  ? 4   FUC K H1  1 
HETATM 17595 H  H2  . FUC K 3 .   ? 212.531 249.853 245.008 1.00 78.06  ? 4   FUC K H2  1 
HETATM 17596 H  H3  . FUC K 3 .   ? 210.739 250.139 242.846 1.00 79.21  ? 4   FUC K H3  1 
HETATM 17597 H  H4  . FUC K 3 .   ? 212.485 250.984 241.636 1.00 79.92  ? 4   FUC K H4  1 
HETATM 17598 H  H5  . FUC K 3 .   ? 211.270 252.519 242.748 1.00 78.53  ? 4   FUC K H5  1 
HETATM 17599 H  H61 . FUC K 3 .   ? 213.959 253.328 243.106 1.00 79.24  ? 4   FUC K H61 1 
HETATM 17600 H  H62 . FUC K 3 .   ? 212.752 254.323 243.003 1.00 77.66  ? 4   FUC K H62 1 
HETATM 17601 H  H63 . FUC K 3 .   ? 213.183 253.472 241.753 1.00 78.49  ? 4   FUC K H63 1 
HETATM 17602 H  HO2 . FUC K 3 .   ? 209.964 249.243 244.970 1.00 77.28  ? 4   FUC K HO2 1 
HETATM 17603 H  HO3 . FUC K 3 .   ? 211.485 248.064 243.244 1.00 81.83  ? 4   FUC K HO3 1 
HETATM 17604 H  HO4 . FUC K 3 .   ? 214.008 250.820 243.793 1.00 79.54  ? 4   FUC K HO4 1 
HETATM 17605 C  C1  . RAM K 3 .   ? 199.914 258.089 252.939 1.00 39.84  ? 5   RAM K C1  1 
HETATM 17606 C  C2  . RAM K 3 .   ? 198.904 258.942 253.715 1.00 42.84  ? 5   RAM K C2  1 
HETATM 17607 C  C3  . RAM K 3 .   ? 198.327 258.198 254.912 1.00 46.97  ? 5   RAM K C3  1 
HETATM 17608 C  C4  . RAM K 3 .   ? 197.739 256.842 254.469 1.00 43.60  ? 5   RAM K C4  1 
HETATM 17609 C  C5  . RAM K 3 .   ? 198.618 256.170 253.397 1.00 44.48  ? 5   RAM K C5  1 
HETATM 17610 C  C6  . RAM K 3 .   ? 198.795 254.689 253.638 1.00 43.81  ? 5   RAM K C6  1 
HETATM 17611 O  O2  . RAM K 3 .   ? 199.569 260.122 254.080 1.00 43.92  ? 5   RAM K O2  1 
HETATM 17612 O  O3  . RAM K 3 .   ? 199.347 258.063 255.871 1.00 50.89  ? 5   RAM K O3  1 
HETATM 17613 O  O4  . RAM K 3 .   ? 196.440 257.083 253.983 1.00 46.00  ? 5   RAM K O4  1 
HETATM 17614 O  O5  . RAM K 3 .   ? 199.900 256.765 253.400 1.00 46.56  ? 5   RAM K O5  1 
HETATM 17615 H  H1  . RAM K 3 .   ? 200.816 258.418 253.074 1.00 39.69  ? 5   RAM K H1  1 
HETATM 17616 H  H2  . RAM K 3 .   ? 198.159 259.140 253.126 1.00 41.56  ? 5   RAM K H2  1 
HETATM 17617 H  H3  . RAM K 3 .   ? 197.592 258.721 255.269 1.00 45.60  ? 5   RAM K H3  1 
HETATM 17618 H  H4  . RAM K 3 .   ? 197.712 256.265 255.247 1.00 44.97  ? 5   RAM K H4  1 
HETATM 17619 H  H5  . RAM K 3 .   ? 198.187 256.296 252.537 1.00 44.90  ? 5   RAM K H5  1 
HETATM 17620 H  H61 . RAM K 3 .   ? 199.332 254.280 252.941 1.00 45.66  ? 5   RAM K H61 1 
HETATM 17621 H  H62 . RAM K 3 .   ? 197.939 254.236 253.675 1.00 45.95  ? 5   RAM K H62 1 
HETATM 17622 H  H63 . RAM K 3 .   ? 199.248 254.536 254.482 1.00 44.13  ? 5   RAM K H63 1 
HETATM 17623 H  HO2 . RAM K 3 .   ? 200.019 260.393 253.414 1.00 39.66  ? 5   RAM K HO2 1 
HETATM 17624 H  HO3 . RAM K 3 .   ? 199.574 258.841 256.130 1.00 45.47  ? 5   RAM K HO3 1 
HETATM 17625 H  HO4 . RAM K 3 .   ? 196.491 257.565 253.284 1.00 43.72  ? 5   RAM K HO4 1 
HETATM 17626 C  C1  . MAN L 3 .   ? 209.419 254.784 263.160 1.00 45.36  ? 1   MAN L C1  1 
HETATM 17627 C  C2  . MAN L 3 .   ? 208.801 254.054 261.959 1.00 47.02  ? 1   MAN L C2  1 
HETATM 17628 C  C3  . MAN L 3 .   ? 207.501 253.389 262.392 1.00 47.39  ? 1   MAN L C3  1 
HETATM 17629 C  C4  . MAN L 3 .   ? 207.913 252.390 263.468 1.00 52.10  ? 1   MAN L C4  1 
HETATM 17630 C  C5  . MAN L 3 .   ? 208.346 253.235 264.666 1.00 50.69  ? 1   MAN L C5  1 
HETATM 17631 C  C6  . MAN L 3 .   ? 208.697 252.373 265.856 1.00 51.51  ? 1   MAN L C6  1 
HETATM 17632 O  O2  . MAN L 3 .   ? 209.640 253.013 261.502 1.00 53.50  ? 1   MAN L O2  1 
HETATM 17633 O  O3  . MAN L 3 .   ? 206.913 252.806 261.257 1.00 50.32  ? 1   MAN L O3  1 
HETATM 17634 O  O4  . MAN L 3 .   ? 206.918 251.431 263.782 1.00 55.09  ? 1   MAN L O4  1 
HETATM 17635 O  O5  . MAN L 3 .   ? 209.503 253.976 264.305 1.00 53.47  ? 1   MAN L O5  1 
HETATM 17636 O  O6  . MAN L 3 .   ? 209.013 253.211 266.939 1.00 53.96  ? 1   MAN L O6  1 
HETATM 17637 H  H1  . MAN L 3 .   ? 210.331 255.050 262.969 1.00 43.67  ? 1   MAN L H1  1 
HETATM 17638 H  H2  . MAN L 3 .   ? 208.619 254.700 261.258 1.00 45.67  ? 1   MAN L H2  1 
HETATM 17639 H  H3  . MAN L 3 .   ? 206.924 254.059 262.791 1.00 47.10  ? 1   MAN L H3  1 
HETATM 17640 H  H4  . MAN L 3 .   ? 208.695 251.912 263.156 1.00 51.95  ? 1   MAN L H4  1 
HETATM 17641 H  H5  . MAN L 3 .   ? 207.617 253.827 264.910 1.00 49.24  ? 1   MAN L H5  1 
HETATM 17642 H  H61 . MAN L 3 .   ? 209.444 251.803 265.615 1.00 50.27  ? 1   MAN L H61 1 
HETATM 17643 H  H62 . MAN L 3 .   ? 207.945 251.793 266.053 1.00 51.98  ? 1   MAN L H62 1 
HETATM 17644 H  HO3 . MAN L 3 .   ? 207.518 252.391 260.830 1.00 49.92  ? 1   MAN L HO3 1 
HETATM 17645 H  HO6 . MAN L 3 .   ? 208.345 253.716 267.083 1.00 51.21  ? 1   MAN L HO6 1 
HETATM 17646 C  C1  . GCU L 3 .   ? 210.970 253.387 261.092 1.00 48.97  ? 2   GCU L C1  1 
HETATM 17647 C  C2  . GCU L 3 .   ? 211.374 252.462 259.931 1.00 50.20  ? 2   GCU L C2  1 
HETATM 17648 C  C3  . GCU L 3 .   ? 211.674 251.042 260.406 1.00 53.00  ? 2   GCU L C3  1 
HETATM 17649 C  C4  . GCU L 3 .   ? 212.752 251.143 261.474 1.00 55.25  ? 2   GCU L C4  1 
HETATM 17650 C  C5  . GCU L 3 .   ? 212.112 251.940 262.622 1.00 54.60  ? 2   GCU L C5  1 
HETATM 17651 C  C6  . GCU L 3 .   ? 212.966 251.985 263.904 1.00 56.05  ? 2   GCU L C6  1 
HETATM 17652 O  O2  . GCU L 3 .   ? 210.359 252.498 258.965 1.00 51.29  ? 2   GCU L O2  1 
HETATM 17653 O  O3  . GCU L 3 .   ? 212.072 250.294 259.281 1.00 58.41  ? 2   GCU L O3  1 
HETATM 17654 O  O4  . GCU L 3 .   ? 213.302 249.887 261.828 1.00 61.15  ? 2   GCU L O4  1 
HETATM 17655 O  O5  . GCU L 3 .   ? 211.877 253.256 262.161 1.00 56.47  ? 2   GCU L O5  1 
HETATM 17656 O  O6A . GCU L 3 .   ? 212.589 251.180 264.796 1.00 59.77  ? 2   GCU L O6A 1 
HETATM 17657 O  O6B . GCU L 3 .   ? 213.906 252.774 263.979 1.00 52.58  ? 2   GCU L O6B 1 
HETATM 17658 H  H1  . GCU L 3 .   ? 211.001 254.318 260.819 1.00 48.19  ? 2   GCU L H1  1 
HETATM 17659 H  H2  . GCU L 3 .   ? 212.196 252.829 259.571 1.00 50.26  ? 2   GCU L H2  1 
HETATM 17660 H  H3  . GCU L 3 .   ? 210.873 250.664 260.803 1.00 52.86  ? 2   GCU L H3  1 
HETATM 17661 H  H4  . GCU L 3 .   ? 213.450 251.706 261.104 1.00 52.62  ? 2   GCU L H4  1 
HETATM 17662 H  H5  . GCU L 3 .   ? 211.276 251.506 262.856 1.00 53.14  ? 2   GCU L H5  1 
HETATM 17663 H  HO2 . GCU L 3 .   ? 209.656 252.177 259.319 1.00 51.66  ? 2   GCU L HO2 1 
HETATM 17664 H  HO3 . GCU L 3 .   ? 212.845 250.558 259.046 1.00 55.08  ? 2   GCU L HO3 1 
HETATM 17665 C  C1  . GLC L 3 .   ? 212.341 248.869 262.193 1.00 67.04  ? 3   GLC L C1  1 
HETATM 17666 C  C2  . GLC L 3 .   ? 212.925 248.052 263.366 1.00 68.49  ? 3   GLC L C2  1 
HETATM 17667 C  C3  . GLC L 3 .   ? 213.988 247.043 262.938 1.00 68.19  ? 3   GLC L C3  1 
HETATM 17668 C  C4  . GLC L 3 .   ? 213.474 246.165 261.807 1.00 68.92  ? 3   GLC L C4  1 
HETATM 17669 C  C5  . GLC L 3 .   ? 213.070 247.108 260.675 1.00 67.26  ? 3   GLC L C5  1 
HETATM 17670 C  C6  . GLC L 3 .   ? 212.514 246.366 259.470 1.00 70.25  ? 3   GLC L C6  1 
HETATM 17671 O  O2  . GLC L 3 .   ? 213.447 248.943 264.311 1.00 63.98  ? 3   GLC L O2  1 
HETATM 17672 O  O3  . GLC L 3 .   ? 214.436 246.289 264.043 1.00 69.71  ? 3   GLC L O3  1 
HETATM 17673 O  O4  . GLC L 3 .   ? 214.463 245.267 261.361 1.00 72.13  ? 3   GLC L O4  1 
HETATM 17674 O  O5  . GLC L 3 .   ? 212.054 247.993 261.121 1.00 72.42  ? 3   GLC L O5  1 
HETATM 17675 O  O6  . GLC L 3 .   ? 213.407 245.415 258.945 1.00 75.16  ? 3   GLC L O6  1 
HETATM 17676 H  H1  . GLC L 3 .   ? 211.493 249.264 262.450 1.00 62.89  ? 3   GLC L H1  1 
HETATM 17677 H  H2  . GLC L 3 .   ? 212.182 247.549 263.734 1.00 67.16  ? 3   GLC L H2  1 
HETATM 17678 H  H3  . GLC L 3 .   ? 214.777 247.510 262.619 1.00 64.67  ? 3   GLC L H3  1 
HETATM 17679 H  H4  . GLC L 3 .   ? 212.682 245.695 262.113 1.00 69.14  ? 3   GLC L H4  1 
HETATM 17680 H  H5  . GLC L 3 .   ? 213.858 247.601 260.399 1.00 63.81  ? 3   GLC L H5  1 
HETATM 17681 H  H61 . GLC L 3 .   ? 212.251 247.015 258.799 1.00 67.17  ? 3   GLC L H61 1 
HETATM 17682 H  H62 . GLC L 3 .   ? 211.713 245.887 259.735 1.00 69.64  ? 3   GLC L H62 1 
HETATM 17683 H  HO2 . GLC L 3 .   ? 214.092 249.362 263.949 1.00 61.34  ? 3   GLC L HO2 1 
HETATM 17684 H  HO3 . GLC L 3 .   ? 213.786 245.830 264.342 1.00 68.82  ? 3   GLC L HO3 1 
HETATM 17685 H  HO6 . GLC L 3 .   ? 213.085 245.124 258.214 1.00 72.45  ? 3   GLC L HO6 1 
HETATM 17686 C  C1  . FUC L 3 .   ? 213.957 243.906 261.361 1.00 80.20  ? 4   FUC L C1  1 
HETATM 17687 C  C2  . FUC L 3 .   ? 214.998 242.998 260.686 1.00 80.07  ? 4   FUC L C2  1 
HETATM 17688 C  C3  . FUC L 3 .   ? 216.267 242.933 261.529 1.00 80.48  ? 4   FUC L C3  1 
HETATM 17689 C  C4  . FUC L 3 .   ? 215.927 242.384 262.912 1.00 81.40  ? 4   FUC L C4  1 
HETATM 17690 C  C5  . FUC L 3 .   ? 214.844 243.273 263.529 1.00 82.44  ? 4   FUC L C5  1 
HETATM 17691 C  C6  . FUC L 3 .   ? 214.316 242.731 264.841 1.00 78.34  ? 4   FUC L C6  1 
HETATM 17692 O  O2  . FUC L 3 .   ? 215.233 243.478 259.388 1.00 77.80  ? 4   FUC L O2  1 
HETATM 17693 O  O3  . FUC L 3 .   ? 217.202 242.145 260.836 1.00 80.06  ? 4   FUC L O3  1 
HETATM 17694 O  O4  . FUC L 3 .   ? 215.526 241.043 262.775 1.00 84.58  ? 4   FUC L O4  1 
HETATM 17695 O  O5  . FUC L 3 .   ? 213.720 243.425 262.665 1.00 84.48  ? 4   FUC L O5  1 
HETATM 17696 H  H1  . FUC L 3 .   ? 213.106 243.852 260.898 1.00 77.45  ? 4   FUC L H1  1 
HETATM 17697 H  H2  . FUC L 3 .   ? 214.610 242.110 260.655 1.00 79.45  ? 4   FUC L H2  1 
HETATM 17698 H  H3  . FUC L 3 .   ? 216.605 243.835 261.653 1.00 78.51  ? 4   FUC L H3  1 
HETATM 17699 H  H4  . FUC L 3 .   ? 216.715 242.455 263.474 1.00 80.12  ? 4   FUC L H4  1 
HETATM 17700 H  H5  . FUC L 3 .   ? 215.255 244.133 263.700 1.00 79.20  ? 4   FUC L H5  1 
HETATM 17701 H  H61 . FUC L 3 .   ? 213.872 241.879 264.707 1.00 79.15  ? 4   FUC L H61 1 
HETATM 17702 H  H62 . FUC L 3 .   ? 213.680 243.335 265.253 1.00 78.42  ? 4   FUC L H62 1 
HETATM 17703 H  H63 . FUC L 3 .   ? 215.046 242.586 265.463 1.00 79.04  ? 4   FUC L H63 1 
HETATM 17704 H  HO2 . FUC L 3 .   ? 215.601 244.241 259.457 1.00 75.84  ? 4   FUC L HO2 1 
HETATM 17705 H  HO3 . FUC L 3 .   ? 216.988 241.327 260.927 1.00 80.94  ? 4   FUC L HO3 1 
HETATM 17706 H  HO4 . FUC L 3 .   ? 214.723 241.023 262.499 1.00 82.42  ? 4   FUC L HO4 1 
HETATM 17707 C  C1  . RAM L 3 .   ? 205.499 251.833 263.568 1.00 54.75  ? 5   RAM L C1  1 
HETATM 17708 C  C2  . RAM L 3 .   ? 204.738 250.766 262.675 1.00 52.71  ? 5   RAM L C2  1 
HETATM 17709 C  C3  . RAM L 3 .   ? 203.233 251.015 262.672 1.00 55.14  ? 5   RAM L C3  1 
HETATM 17710 C  C4  . RAM L 3 .   ? 202.675 251.094 264.113 1.00 57.08  ? 5   RAM L C4  1 
HETATM 17711 C  C5  . RAM L 3 .   ? 203.779 251.172 265.189 1.00 55.07  ? 5   RAM L C5  1 
HETATM 17712 C  C6  . RAM L 3 .   ? 203.261 251.594 266.547 1.00 55.55  ? 5   RAM L C6  1 
HETATM 17713 O  O2  . RAM L 3 .   ? 205.312 250.798 261.397 1.00 50.84  ? 5   RAM L O2  1 
HETATM 17714 O  O3  . RAM L 3 .   ? 202.991 252.179 261.922 1.00 58.11  ? 5   RAM L O3  1 
HETATM 17715 O  O4  . RAM L 3 .   ? 201.886 249.945 264.311 1.00 61.60  ? 5   RAM L O4  1 
HETATM 17716 O  O5  . RAM L 3 .   ? 204.765 252.119 264.798 1.00 57.49  ? 5   RAM L O5  1 
HETATM 17717 H  H1  . RAM L 3 .   ? 205.506 251.048 264.123 1.00 53.73  ? 5   RAM L H1  1 
HETATM 17718 H  H2  . RAM L 3 .   ? 204.868 249.888 263.070 1.00 53.21  ? 5   RAM L H2  1 
HETATM 17719 H  H3  . RAM L 3 .   ? 202.804 250.253 262.251 1.00 55.67  ? 5   RAM L H3  1 
HETATM 17720 H  H4  . RAM L 3 .   ? 202.131 251.894 264.172 1.00 55.41  ? 5   RAM L H4  1 
HETATM 17721 H  H5  . RAM L 3 .   ? 204.144 250.277 265.295 1.00 55.32  ? 5   RAM L H5  1 
HETATM 17722 H  H61 . RAM L 3 .   ? 203.970 251.587 267.209 1.00 54.72  ? 5   RAM L H61 1 
HETATM 17723 H  H62 . RAM L 3 .   ? 202.554 251.003 266.846 1.00 55.65  ? 5   RAM L H62 1 
HETATM 17724 H  H63 . RAM L 3 .   ? 202.903 252.494 266.512 1.00 54.38  ? 5   RAM L H63 1 
HETATM 17725 H  HO2 . RAM L 3 .   ? 205.046 251.503 261.004 1.00 52.56  ? 5   RAM L HO2 1 
HETATM 17726 H  HO3 . RAM L 3 .   ? 203.650 252.704 262.023 1.00 55.07  ? 5   RAM L HO3 1 
HETATM 17727 H  HO4 . RAM L 3 .   ? 201.210 249.981 263.796 1.00 59.06  ? 5   RAM L HO4 1 
HETATM 17728 CA CA  . CA  M 4 .   ? 250.534 267.713 247.092 1.00 24.17  ? 501 CA  A CA  1 
HETATM 17729 C  C1  . MAN N 5 .   ? 289.358 292.763 278.331 1.00 74.95  ? 401 MAN B C1  1 
HETATM 17730 C  C2  . MAN N 5 .   ? 289.385 291.490 277.490 1.00 72.80  ? 401 MAN B C2  1 
HETATM 17731 C  C3  . MAN N 5 .   ? 290.281 290.461 278.168 1.00 71.92  ? 401 MAN B C3  1 
HETATM 17732 C  C4  . MAN N 5 .   ? 291.664 291.045 278.431 1.00 73.78  ? 401 MAN B C4  1 
HETATM 17733 C  C5  . MAN N 5 .   ? 291.547 292.384 279.171 1.00 76.68  ? 401 MAN B C5  1 
HETATM 17734 C  C6  . MAN N 5 .   ? 292.882 293.093 279.246 1.00 77.90  ? 401 MAN B C6  1 
HETATM 17735 O  O2  . MAN N 5 .   ? 289.864 291.846 276.216 1.00 74.66  ? 401 MAN B O2  1 
HETATM 17736 O  O3  . MAN N 5 .   ? 290.338 289.332 277.329 1.00 68.29  ? 401 MAN B O3  1 
HETATM 17737 O  O4  . MAN N 5 .   ? 292.369 290.091 279.197 1.00 70.10  ? 401 MAN B O4  1 
HETATM 17738 O  O5  . MAN N 5 .   ? 290.656 293.252 278.494 1.00 76.54  ? 401 MAN B O5  1 
HETATM 17739 O  O6  . MAN N 5 .   ? 293.323 293.373 277.940 1.00 76.84  ? 401 MAN B O6  1 
HETATM 17740 H  H1  . MAN N 5 .   ? 288.893 293.460 277.842 1.00 72.82  ? 401 MAN B H1  1 
HETATM 17741 H  H2  . MAN N 5 .   ? 288.485 291.135 277.428 1.00 68.94  ? 401 MAN B H2  1 
HETATM 17742 H  H3  . MAN N 5 .   ? 289.885 290.233 279.024 1.00 70.77  ? 401 MAN B H3  1 
HETATM 17743 H  H4  . MAN N 5 .   ? 292.104 291.196 277.580 1.00 73.83  ? 401 MAN B H4  1 
HETATM 17744 H  H5  . MAN N 5 .   ? 291.236 292.210 280.073 1.00 74.39  ? 401 MAN B H5  1 
HETATM 17745 H  H61 . MAN N 5 .   ? 293.508 292.520 279.715 1.00 76.10  ? 401 MAN B H61 1 
HETATM 17746 H  H62 . MAN N 5 .   ? 292.781 293.900 279.775 1.00 76.69  ? 401 MAN B H62 1 
HETATM 17747 H  HO2 . MAN N 5 .   ? 289.979 291.131 275.772 1.00 72.58  ? 401 MAN B HO2 1 
HETATM 17748 H  HO3 . MAN N 5 .   ? 289.570 288.967 277.327 1.00 66.13  ? 401 MAN B HO3 1 
HETATM 17749 H  HO4 . MAN N 5 .   ? 292.233 290.238 280.023 1.00 69.96  ? 401 MAN B HO4 1 
HETATM 17750 H  HO6 . MAN N 5 .   ? 292.729 293.846 277.556 1.00 76.02  ? 401 MAN B HO6 1 
HETATM 17751 C  C1  . MAN O 5 .   ? 284.497 286.606 246.766 1.00 100.36 ? 402 MAN B C1  1 
HETATM 17752 C  C2  . MAN O 5 .   ? 285.490 286.239 247.867 1.00 102.60 ? 402 MAN B C2  1 
HETATM 17753 C  C3  . MAN O 5 .   ? 286.900 286.678 247.481 1.00 102.37 ? 402 MAN B C3  1 
HETATM 17754 C  C4  . MAN O 5 .   ? 287.262 286.170 246.091 1.00 101.72 ? 402 MAN B C4  1 
HETATM 17755 C  C5  . MAN O 5 .   ? 286.192 286.628 245.095 1.00 102.10 ? 402 MAN B C5  1 
HETATM 17756 C  C6  . MAN O 5 .   ? 286.451 286.095 243.701 1.00 99.61  ? 402 MAN B C6  1 
HETATM 17757 O  O2  . MAN O 5 .   ? 285.407 284.845 248.045 1.00 103.48 ? 402 MAN B O2  1 
HETATM 17758 O  O3  . MAN O 5 .   ? 287.780 286.186 248.464 1.00 100.14 ? 402 MAN B O3  1 
HETATM 17759 O  O4  . MAN O 5 .   ? 288.536 286.691 245.776 1.00 101.38 ? 402 MAN B O4  1 
HETATM 17760 O  O5  . MAN O 5 .   ? 284.921 286.158 245.510 1.00 100.42 ? 402 MAN B O5  1 
HETATM 17761 O  O6  . MAN O 5 .   ? 287.591 286.729 243.173 1.00 100.05 ? 402 MAN B O6  1 
HETATM 17762 H  H1  . MAN O 5 .   ? 283.660 286.140 246.921 1.00 100.42 ? 402 MAN B H1  1 
HETATM 17763 H  H2  . MAN O 5 .   ? 285.227 286.704 248.677 1.00 101.58 ? 402 MAN B H2  1 
HETATM 17764 H  H3  . MAN O 5 .   ? 286.918 287.647 247.458 1.00 101.81 ? 402 MAN B H3  1 
HETATM 17765 H  H4  . MAN O 5 .   ? 287.279 285.201 246.108 1.00 98.31  ? 402 MAN B H4  1 
HETATM 17766 H  H5  . MAN O 5 .   ? 286.201 287.597 245.061 1.00 101.65 ? 402 MAN B H5  1 
HETATM 17767 H  H61 . MAN O 5 .   ? 285.668 286.270 243.156 1.00 98.91  ? 402 MAN B H61 1 
HETATM 17768 H  H62 . MAN O 5 .   ? 286.559 285.133 243.745 1.00 96.54  ? 402 MAN B H62 1 
HETATM 17769 H  HO2 . MAN O 5 .   ? 285.516 284.479 247.286 1.00 99.35  ? 402 MAN B HO2 1 
HETATM 17770 H  HO3 . MAN O 5 .   ? 287.630 285.355 248.558 1.00 100.36 ? 402 MAN B HO3 1 
HETATM 17771 H  HO4 . MAN O 5 .   ? 288.446 287.427 245.361 1.00 101.38 ? 402 MAN B HO4 1 
HETATM 17772 H  HO6 . MAN O 5 .   ? 287.421 287.558 243.096 1.00 100.44 ? 402 MAN B HO6 1 
HETATM 17773 CA CA  . CA  P 4 .   ? 291.992 256.762 247.146 1.00 24.62  ? 501 CA  C CA  1 
HETATM 17774 C  C1  . MAN Q 5 .   ? 325.409 288.229 278.446 1.00 74.89  ? 401 MAN D C1  1 
HETATM 17775 C  C2  . MAN Q 5 .   ? 325.660 286.892 277.755 1.00 72.45  ? 401 MAN D C2  1 
HETATM 17776 C  C3  . MAN Q 5 .   ? 326.735 286.126 278.516 1.00 73.49  ? 401 MAN D C3  1 
HETATM 17777 C  C4  . MAN Q 5 .   ? 327.990 286.976 278.665 1.00 74.03  ? 401 MAN D C4  1 
HETATM 17778 C  C5  . MAN Q 5 .   ? 327.636 288.332 279.288 1.00 75.23  ? 401 MAN D C5  1 
HETATM 17779 C  C6  . MAN Q 5 .   ? 328.822 289.273 279.270 1.00 78.18  ? 401 MAN D C6  1 
HETATM 17780 O  O2  . MAN Q 5 .   ? 326.048 287.172 276.432 1.00 74.43  ? 401 MAN D O2  1 
HETATM 17781 O  O3  . MAN Q 5 .   ? 326.991 284.936 277.809 1.00 71.93  ? 401 MAN D O3  1 
HETATM 17782 O  O4  . MAN Q 5 .   ? 328.883 286.245 279.477 1.00 74.95  ? 401 MAN D O4  1 
HETATM 17783 O  O5  . MAN Q 5 .   ? 326.595 288.960 278.561 1.00 73.98  ? 401 MAN D O5  1 
HETATM 17784 O  O6  . MAN Q 5 .   ? 329.193 289.515 277.935 1.00 79.50  ? 401 MAN D O6  1 
HETATM 17785 H  H1  . MAN Q 5 .   ? 324.834 288.777 277.890 1.00 72.88  ? 401 MAN D H1  1 
HETATM 17786 H  H2  . MAN Q 5 .   ? 324.838 286.379 277.766 1.00 68.52  ? 401 MAN D H2  1 
HETATM 17787 H  H3  . MAN Q 5 .   ? 326.397 285.934 279.405 1.00 71.42  ? 401 MAN D H3  1 
HETATM 17788 H  H4  . MAN Q 5 .   ? 328.370 287.126 277.785 1.00 74.54  ? 401 MAN D H4  1 
HETATM 17789 H  H5  . MAN Q 5 .   ? 327.370 288.185 280.209 1.00 74.31  ? 401 MAN D H5  1 
HETATM 17790 H  H61 . MAN Q 5 .   ? 329.546 288.864 279.769 1.00 76.50  ? 401 MAN D H61 1 
HETATM 17791 H  H62 . MAN Q 5 .   ? 328.582 290.091 279.733 1.00 77.30  ? 401 MAN D H62 1 
HETATM 17792 H  HO2 . MAN Q 5 .   ? 326.262 286.437 276.063 1.00 70.46  ? 401 MAN D HO2 1 
HETATM 17793 H  HO3 . MAN Q 5 .   ? 326.285 284.462 277.828 1.00 67.70  ? 401 MAN D HO3 1 
HETATM 17794 H  HO4 . MAN Q 5 .   ? 328.743 286.436 280.293 1.00 72.55  ? 401 MAN D HO4 1 
HETATM 17795 H  HO6 . MAN Q 5 .   ? 328.519 289.832 277.527 1.00 77.56  ? 401 MAN D HO6 1 
HETATM 17796 C  C1  . MAN R 5 .   ? 321.846 281.728 246.630 1.00 114.15 ? 402 MAN D C1  1 
HETATM 17797 C  C2  . MAN R 5 .   ? 323.111 281.553 247.467 1.00 115.82 ? 402 MAN D C2  1 
HETATM 17798 C  C3  . MAN R 5 .   ? 324.284 282.280 246.815 1.00 118.96 ? 402 MAN D C3  1 
HETATM 17799 C  C4  . MAN R 5 .   ? 324.419 281.893 245.347 1.00 116.84 ? 402 MAN D C4  1 
HETATM 17800 C  C5  . MAN R 5 .   ? 323.084 282.123 244.632 1.00 116.72 ? 402 MAN D C5  1 
HETATM 17801 C  C6  . MAN R 5 .   ? 323.124 281.660 243.190 1.00 113.74 ? 402 MAN D C6  1 
HETATM 17802 O  O2  . MAN R 5 .   ? 323.344 280.170 247.573 1.00 113.48 ? 402 MAN D O2  1 
HETATM 17803 O  O3  . MAN R 5 .   ? 325.442 281.960 247.551 1.00 117.59 ? 402 MAN D O3  1 
HETATM 17804 O  O4  . MAN R 5 .   ? 325.447 282.692 244.803 1.00 114.73 ? 402 MAN D O4  1 
HETATM 17805 O  O5  . MAN R 5 .   ? 322.059 281.395 245.288 1.00 116.39 ? 402 MAN D O5  1 
HETATM 17806 O  O6  . MAN R 5 .   ? 324.081 282.417 242.489 1.00 114.85 ? 402 MAN D O6  1 
HETATM 17807 H  H1  . MAN R 5 .   ? 321.171 281.100 246.932 1.00 113.58 ? 402 MAN D H1  1 
HETATM 17808 H  H2  . MAN R 5 .   ? 322.949 281.941 248.341 1.00 115.15 ? 402 MAN D H2  1 
HETATM 17809 H  H3  . MAN R 5 .   ? 324.106 283.233 246.854 1.00 117.50 ? 402 MAN D H3  1 
HETATM 17810 H  H4  . MAN R 5 .   ? 324.647 280.951 245.292 1.00 111.45 ? 402 MAN D H4  1 
HETATM 17811 H  H5  . MAN R 5 .   ? 322.890 283.073 244.646 1.00 115.78 ? 402 MAN D H5  1 
HETATM 17812 H  H61 . MAN R 5 .   ? 322.240 281.771 242.808 1.00 112.95 ? 402 MAN D H61 1 
HETATM 17813 H  H62 . MAN R 5 .   ? 323.327 280.711 243.169 1.00 110.63 ? 402 MAN D H62 1 
HETATM 17814 H  HO2 . MAN R 5 .   ? 324.041 279.986 247.122 1.00 110.99 ? 402 MAN D HO2 1 
HETATM 17815 H  HO3 . MAN R 5 .   ? 325.486 281.115 247.622 1.00 115.30 ? 402 MAN D HO3 1 
HETATM 17816 H  HO4 . MAN R 5 .   ? 325.114 283.417 244.508 1.00 115.19 ? 402 MAN D HO4 1 
HETATM 17817 H  HO6 . MAN R 5 .   ? 323.839 283.231 242.505 1.00 115.01 ? 402 MAN D HO6 1 
HETATM 17818 CA CA  . CA  S 4 .   ? 212.075 286.872 247.092 1.00 18.96  ? 501 CA  E CA  1 
HETATM 17819 C  C1  . MAN T 5 .   ? 255.074 303.547 278.326 1.00 77.33  ? 401 MAN F C1  1 
HETATM 17820 C  C2  . MAN T 5 .   ? 254.856 302.213 277.617 1.00 75.59  ? 401 MAN F C2  1 
HETATM 17821 C  C3  . MAN T 5 .   ? 255.594 301.121 278.378 1.00 75.22  ? 401 MAN F C3  1 
HETATM 17822 C  C4  . MAN T 5 .   ? 257.069 301.481 278.517 1.00 77.63  ? 401 MAN F C4  1 
HETATM 17823 C  C5  . MAN T 5 .   ? 257.219 302.888 279.112 1.00 77.29  ? 401 MAN F C5  1 
HETATM 17824 C  C6  . MAN T 5 .   ? 258.652 303.370 279.053 1.00 79.79  ? 401 MAN F C6  1 
HETATM 17825 O  O2  . MAN T 5 .   ? 255.346 302.351 276.305 1.00 75.57  ? 401 MAN F O2  1 
HETATM 17826 O  O3  . MAN T 5 .   ? 255.405 299.917 277.673 1.00 70.37  ? 401 MAN F O3  1 
HETATM 17827 O  O4  . MAN T 5 .   ? 257.652 300.501 279.348 1.00 75.29  ? 401 MAN F O4  1 
HETATM 17828 O  O5  . MAN T 5 .   ? 256.442 303.822 278.382 1.00 77.53  ? 401 MAN F O5  1 
HETATM 17829 O  O6  . MAN T 5 .   ? 258.989 303.646 277.715 1.00 81.14  ? 401 MAN F O6  1 
HETATM 17830 H  H1  . MAN T 5 .   ? 254.703 304.261 277.785 1.00 74.67  ? 401 MAN F H1  1 
HETATM 17831 H  H2  . MAN T 5 .   ? 253.909 302.010 277.606 1.00 70.26  ? 401 MAN F H2  1 
HETATM 17832 H  H3  . MAN T 5 .   ? 255.213 301.063 279.269 1.00 73.46  ? 401 MAN F H3  1 
HETATM 17833 H  H4  . MAN T 5 .   ? 257.476 301.471 277.637 1.00 76.90  ? 401 MAN F H4  1 
HETATM 17834 H  H5  . MAN T 5 .   ? 256.938 302.860 280.040 1.00 75.91  ? 401 MAN F H5  1 
HETATM 17835 H  H61 . MAN T 5 .   ? 259.224 302.682 279.427 1.00 78.52  ? 401 MAN F H61 1 
HETATM 17836 H  H62 . MAN T 5 .   ? 258.743 304.154 279.616 1.00 79.09  ? 401 MAN F H62 1 
HETATM 17837 H  HO2 . MAN T 5 .   ? 255.316 301.587 275.934 1.00 72.21  ? 401 MAN F HO2 1 
HETATM 17838 H  HO3 . MAN T 5 .   ? 254.581 299.712 277.718 1.00 67.32  ? 401 MAN F HO3 1 
HETATM 17839 H  HO4 . MAN T 5 .   ? 257.578 300.740 280.161 1.00 74.01  ? 401 MAN F HO4 1 
HETATM 17840 H  HO6 . MAN T 5 .   ? 258.489 304.277 277.441 1.00 79.24  ? 401 MAN F HO6 1 
HETATM 17841 C  C1  . MAN U 5 .   ? 248.892 298.900 246.452 1.00 110.36 ? 402 MAN F C1  1 
HETATM 17842 C  C2  . MAN U 5 .   ? 249.644 298.519 247.726 1.00 111.48 ? 402 MAN F C2  1 
HETATM 17843 C  C3  . MAN U 5 .   ? 251.152 298.525 247.485 1.00 111.90 ? 402 MAN F C3  1 
HETATM 17844 C  C4  . MAN U 5 .   ? 251.506 297.713 246.245 1.00 109.75 ? 402 MAN F C4  1 
HETATM 17845 C  C5  . MAN U 5 .   ? 250.712 298.259 245.055 1.00 108.79 ? 402 MAN F C5  1 
HETATM 17846 C  C6  . MAN U 5 .   ? 250.978 297.478 243.785 1.00 106.52 ? 402 MAN F C6  1 
HETATM 17847 O  O2  . MAN U 5 .   ? 249.181 297.246 248.110 1.00 110.15 ? 402 MAN F O2  1 
HETATM 17848 O  O3  . MAN U 5 .   ? 251.766 298.008 248.642 1.00 111.76 ? 402 MAN F O3  1 
HETATM 17849 O  O4  . MAN U 5 .   ? 252.900 297.831 246.052 1.00 108.92 ? 402 MAN F O4  1 
HETATM 17850 O  O5  . MAN U 5 .   ? 249.326 298.172 245.339 1.00 109.11 ? 402 MAN F O5  1 
HETATM 17851 O  O6  . MAN U 5 .   ? 252.326 297.640 243.416 1.00 108.99 ? 402 MAN F O6  1 
HETATM 17852 H  H1  . MAN U 5 .   ? 247.956 298.663 246.549 1.00 109.54 ? 402 MAN F H1  1 
HETATM 17853 H  H2  . MAN U 5 .   ? 249.434 299.177 248.407 1.00 110.05 ? 402 MAN F H2  1 
HETATM 17854 H  H3  . MAN U 5 .   ? 251.429 299.441 247.329 1.00 110.61 ? 402 MAN F H3  1 
HETATM 17855 H  H4  . MAN U 5 .   ? 251.254 296.789 246.394 1.00 105.01 ? 402 MAN F H4  1 
HETATM 17856 H  H5  . MAN U 5 .   ? 250.973 299.182 244.911 1.00 108.75 ? 402 MAN F H5  1 
HETATM 17857 H  H61 . MAN U 5 .   ? 250.382 297.807 243.093 1.00 105.35 ? 402 MAN F H61 1 
HETATM 17858 H  H62 . MAN U 5 .   ? 250.754 296.547 243.934 1.00 102.27 ? 402 MAN F H62 1 
HETATM 17859 H  HO2 . MAN U 5 .   ? 249.317 296.714 247.462 1.00 106.10 ? 402 MAN F HO2 1 
HETATM 17860 H  HO3 . MAN U 5 .   ? 251.414 297.253 248.812 1.00 110.47 ? 402 MAN F HO3 1 
HETATM 17861 H  HO4 . MAN U 5 .   ? 253.059 298.487 245.536 1.00 109.80 ? 402 MAN F HO4 1 
HETATM 17862 H  HO6 . MAN U 5 .   ? 252.453 298.460 243.232 1.00 108.43 ? 402 MAN F HO6 1 
HETATM 17863 O  O   . HOH V 6 .   ? 251.627 268.674 248.596 1.00 22.64  ? 601 HOH A O   1 
HETATM 17864 H  H1  . HOH V 6 .   ? 251.934 269.464 248.528 1.00 22.87  ? 601 HOH A H1  1 
HETATM 17865 H  H2  . HOH V 6 .   ? 251.735 268.484 249.418 1.00 22.71  ? 601 HOH A H2  1 
HETATM 17866 O  O   . HOH W 6 .   ? 292.761 257.773 248.801 1.00 19.52  ? 601 HOH C O   1 
HETATM 17867 H  H1  . HOH W 6 .   ? 292.769 258.621 248.854 1.00 19.89  ? 601 HOH C H1  1 
HETATM 17868 H  H2  . HOH W 6 .   ? 293.262 257.523 249.441 1.00 19.75  ? 601 HOH C H2  1 
HETATM 17869 O  O   . HOH X 6 .   ? 213.351 287.243 248.650 1.00 16.40  ? 601 HOH E O   1 
HETATM 17870 H  H1  . HOH X 6 .   ? 213.781 287.974 248.588 1.00 17.06  ? 601 HOH E H1  1 
HETATM 17871 H  H2  . HOH X 6 .   ? 213.628 286.904 249.377 1.00 17.35  ? 601 HOH E H2  1 
# 
