data_9MUP
# 
_entry.id   9MUP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MUP         pdb_00009mup 10.2210/pdb9mup/pdb 
WWPDB D_1000291886 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-09 ? 
2 'Structure model' 1 1 2025-04-30 ? 
3 'Structure model' 1 2 2025-05-14 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Database references' 
2 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 3 'Structure model' citation        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.pdbx_database_id_DOI'    
7  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  2 'Structure model' '_citation.title'                   
9  2 'Structure model' '_citation.year'                    
10 3 'Structure model' '_citation.journal_volume'          
11 3 'Structure model' '_citation.page_first'              
12 3 'Structure model' '_citation.page_last'               
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MUP 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-14 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              whitman@austin.utexas.edu 
_pdbx_contact_author.name_first         Christian 
_pdbx_contact_author.name_last          Whitman 
_pdbx_contact_author.name_mi            P. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7566-1346 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Melkonian, T.R.' 1 0000-0001-7566-1346 
'Vuksanovic, N.'  2 0000-0003-2883-6312 
'Allen, K.N.'     3 0000-0001-7296-0551 
'Whitman, C.P.'   4 0000-0002-8231-2483 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? US ? ? primary Biochemistry                     BICHAW 0033 0006-2960 ? ? 64 ? 1950 1962 
'Beyond the beta-alpha-beta Fold: Characterization of a SnoaL Domain in the Tautomerase Superfamily.'         2025 ? 
10.1021/acs.biochem.5c00051 40231412 ? ? 
? ? ? ? ? ? ? ?  ? ? 1       'Acta Crystallogr D Struct Biol' ?      ?    2059-7983 ? ? 75 ? 861  877  
'Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix.' 2019 ? 
10.1107/S2059798319011471   31588918 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Melkonian, T.R.'   1  0000-0001-7566-1346 
primary 'Vuksanovic, N.'    2  0000-0003-2883-6312 
primary 'Person, M.D.'      3  0000-0001-8161-9339 
primary 'Chen, T.Y.'        4  ?                   
primary 'Chang, W.C.'       5  0000-0002-2341-9846 
primary 'Allen, K.N.'       6  0000-0001-7296-0551 
primary 'Whitman, C.P.'     7  0000-0002-8231-2483 
1       'Liebschner, D.'    8  0000-0003-3921-3209 
1       'Afonine, P.V.'     9  0000-0002-5052-991X 
1       'Baker, M.L.'       10 ?                   
1       'Bunkoczi, G.'      11 ?                   
1       'Chen, V.B.'        12 ?                   
1       'Croll, T.I.'       13 ?                   
1       'Hintze, B.'        14 0000-0002-4871-2096 
1       'Hung, L.W.'        15 0000-0001-6690-8458 
1       'Jain, S.'          16 ?                   
1       'McCoy, A.J.'       17 ?                   
1       'Moriarty, N.W.'    18 0000-0001-8857-9464 
1       'Oeffner, R.D.'     19 0000-0003-3107-2202 
1       'Poon, B.K.'        20 0000-0001-9633-6067 
1       'Prisant, M.G.'     21 ?                   
1       'Read, R.J.'        22 0000-0001-8273-0047 
1       'Richardson, J.S.'  23 ?                   
1       'Richardson, D.C.'  24 ?                   
1       'Sammito, M.D.'     25 ?                   
1       'Sobolev, O.V.'     26 0000-0002-0623-3214 
1       'Stockwell, D.H.'   27 ?                   
1       'Terwilliger, T.C.' 28 0000-0001-6384-0320 
1       'Urzhumtsev, A.G.'  29 ?                   
1       'Videau, L.L.'      30 ?                   
1       'Williams, C.J.'    31 ?                   
1       'Adams, P.D.'       32 0000-0001-9333-8219 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man Tautomerase 21123.844 1  ? ? ? ? 
2 water   nat water       18.015    57 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;(ZI0)IVEIHLLEGYSDAEKERLGRSLTAAVQTVVPAPPEAITVMMHEMQAADYMRGATRRTPAPALPDAAATVRDFLDT
MEARDLDKARTFLTDDFVMTFPTGRRMTDLSDLVEWSATRYRFVTKTYDRFDTAATLDGPVVYCFGTLRGEWPDGTPFDN
VRFIDRFALRDGKLAVQDVWNDLEAMRPRG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;PIVEIHLLEGYSDAEKERLGRSLTAAVQTVVPAPPEAITVMMHEMQAADYMRGATRRTPAPALPDAAATVRDFLDTMEAR
DLDKARTFLTDDFVMTFPTGRRMTDLSDLVEWSATRYRFVTKTYDRFDTAATLDGPVVYCFGTLRGEWPDGTPFDNVRFI
DRFALRDGKLAVQDVWNDLEAMRPRG
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ZI0 n 
1 2   ILE n 
1 3   VAL n 
1 4   GLU n 
1 5   ILE n 
1 6   HIS n 
1 7   LEU n 
1 8   LEU n 
1 9   GLU n 
1 10  GLY n 
1 11  TYR n 
1 12  SER n 
1 13  ASP n 
1 14  ALA n 
1 15  GLU n 
1 16  LYS n 
1 17  GLU n 
1 18  ARG n 
1 19  LEU n 
1 20  GLY n 
1 21  ARG n 
1 22  SER n 
1 23  LEU n 
1 24  THR n 
1 25  ALA n 
1 26  ALA n 
1 27  VAL n 
1 28  GLN n 
1 29  THR n 
1 30  VAL n 
1 31  VAL n 
1 32  PRO n 
1 33  ALA n 
1 34  PRO n 
1 35  PRO n 
1 36  GLU n 
1 37  ALA n 
1 38  ILE n 
1 39  THR n 
1 40  VAL n 
1 41  MET n 
1 42  MET n 
1 43  HIS n 
1 44  GLU n 
1 45  MET n 
1 46  GLN n 
1 47  ALA n 
1 48  ALA n 
1 49  ASP n 
1 50  TYR n 
1 51  MET n 
1 52  ARG n 
1 53  GLY n 
1 54  ALA n 
1 55  THR n 
1 56  ARG n 
1 57  ARG n 
1 58  THR n 
1 59  PRO n 
1 60  ALA n 
1 61  PRO n 
1 62  ALA n 
1 63  LEU n 
1 64  PRO n 
1 65  ASP n 
1 66  ALA n 
1 67  ALA n 
1 68  ALA n 
1 69  THR n 
1 70  VAL n 
1 71  ARG n 
1 72  ASP n 
1 73  PHE n 
1 74  LEU n 
1 75  ASP n 
1 76  THR n 
1 77  MET n 
1 78  GLU n 
1 79  ALA n 
1 80  ARG n 
1 81  ASP n 
1 82  LEU n 
1 83  ASP n 
1 84  LYS n 
1 85  ALA n 
1 86  ARG n 
1 87  THR n 
1 88  PHE n 
1 89  LEU n 
1 90  THR n 
1 91  ASP n 
1 92  ASP n 
1 93  PHE n 
1 94  VAL n 
1 95  MET n 
1 96  THR n 
1 97  PHE n 
1 98  PRO n 
1 99  THR n 
1 100 GLY n 
1 101 ARG n 
1 102 ARG n 
1 103 MET n 
1 104 THR n 
1 105 ASP n 
1 106 LEU n 
1 107 SER n 
1 108 ASP n 
1 109 LEU n 
1 110 VAL n 
1 111 GLU n 
1 112 TRP n 
1 113 SER n 
1 114 ALA n 
1 115 THR n 
1 116 ARG n 
1 117 TYR n 
1 118 ARG n 
1 119 PHE n 
1 120 VAL n 
1 121 THR n 
1 122 LYS n 
1 123 THR n 
1 124 TYR n 
1 125 ASP n 
1 126 ARG n 
1 127 PHE n 
1 128 ASP n 
1 129 THR n 
1 130 ALA n 
1 131 ALA n 
1 132 THR n 
1 133 LEU n 
1 134 ASP n 
1 135 GLY n 
1 136 PRO n 
1 137 VAL n 
1 138 VAL n 
1 139 TYR n 
1 140 CYS n 
1 141 PHE n 
1 142 GLY n 
1 143 THR n 
1 144 LEU n 
1 145 ARG n 
1 146 GLY n 
1 147 GLU n 
1 148 TRP n 
1 149 PRO n 
1 150 ASP n 
1 151 GLY n 
1 152 THR n 
1 153 PRO n 
1 154 PHE n 
1 155 ASP n 
1 156 ASN n 
1 157 VAL n 
1 158 ARG n 
1 159 PHE n 
1 160 ILE n 
1 161 ASP n 
1 162 ARG n 
1 163 PHE n 
1 164 ALA n 
1 165 LEU n 
1 166 ARG n 
1 167 ASP n 
1 168 GLY n 
1 169 LYS n 
1 170 LEU n 
1 171 ALA n 
1 172 VAL n 
1 173 GLN n 
1 174 ASP n 
1 175 VAL n 
1 176 TRP n 
1 177 ASN n 
1 178 ASP n 
1 179 LEU n 
1 180 GLU n 
1 181 ALA n 
1 182 MET n 
1 183 ARG n 
1 184 PRO n 
1 185 ARG n 
1 186 GLY n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   186 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ATO9_16250 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Pseudooceanicola atlanticus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1461694 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ?                                                                       'C3 H7 N O2' 
89.093  
ARG 'L-peptide linking' y ARGININE          ?                                                                       
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ?                                                                       'C4 H8 N2 O3' 
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ?                                                                       'C4 H7 N O4' 
133.103 
CYS 'L-peptide linking' y CYSTEINE          ?                                                                       'C3 H7 N O2 S' 
121.158 
GLN 'L-peptide linking' y GLUTAMINE         ?                                                                       'C5 H10 N2 O3' 
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ?                                                                       'C5 H9 N O4' 
147.129 
GLY 'peptide linking'   y GLYCINE           ?                                                                       'C2 H5 N O2' 
75.067  
HIS 'L-peptide linking' y HISTIDINE         ?                                                                       
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER             ?                                                                       'H2 O' 18.015  
ILE 'L-peptide linking' y ISOLEUCINE        ?                                                                       'C6 H13 N O2' 
131.173 
LEU 'L-peptide linking' y LEUCINE           ?                                                                       'C6 H13 N O2' 
131.173 
LYS 'L-peptide linking' y LYSINE            ?                                                                       
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ?                                                                       
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE     ?                                                                       'C9 H11 N O2' 
165.189 
PRO 'L-peptide linking' y PROLINE           ?                                                                       'C5 H9 N O2' 
115.130 
SER 'L-peptide linking' y SERINE            ?                                                                       'C3 H7 N O3' 
105.093 
THR 'L-peptide linking' y THREONINE         ?                                                                       'C4 H9 N O3' 
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN        ?                                                                       
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE          ?                                                                       'C9 H11 N O3' 
181.189 
VAL 'L-peptide linking' y VALINE            ?                                                                       'C5 H11 N O2' 
117.146 
ZI0 'L-peptide linking' n N-MALONYL-PROLINE '1-(3-oxidanyl-3-oxidanylidene-propanoyl)pyrrolidine-2-carboxylic acid' 'C8 H11 N O5' 
201.177 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ZI0 1   1   1   ZI0 LIG A . n 
A 1 2   ILE 2   3   2   ILE ILE A . n 
A 1 3   VAL 3   4   3   VAL VAL A . n 
A 1 4   GLU 4   5   4   GLU GLU A . n 
A 1 5   ILE 5   6   5   ILE ILE A . n 
A 1 6   HIS 6   7   6   HIS HIS A . n 
A 1 7   LEU 7   8   7   LEU LEU A . n 
A 1 8   LEU 8   9   8   LEU LEU A . n 
A 1 9   GLU 9   10  9   GLU GLU A . n 
A 1 10  GLY 10  11  10  GLY GLY A . n 
A 1 11  TYR 11  12  11  TYR TYR A . n 
A 1 12  SER 12  13  12  SER SER A . n 
A 1 13  ASP 13  14  13  ASP ASP A . n 
A 1 14  ALA 14  15  14  ALA ALA A . n 
A 1 15  GLU 15  16  15  GLU GLU A . n 
A 1 16  LYS 16  17  16  LYS LYS A . n 
A 1 17  GLU 17  18  17  GLU GLU A . n 
A 1 18  ARG 18  19  18  ARG ARG A . n 
A 1 19  LEU 19  20  19  LEU LEU A . n 
A 1 20  GLY 20  21  20  GLY GLY A . n 
A 1 21  ARG 21  22  21  ARG ARG A . n 
A 1 22  SER 22  23  22  SER SER A . n 
A 1 23  LEU 23  24  23  LEU LEU A . n 
A 1 24  THR 24  25  24  THR THR A . n 
A 1 25  ALA 25  26  25  ALA ALA A . n 
A 1 26  ALA 26  27  26  ALA ALA A . n 
A 1 27  VAL 27  28  27  VAL VAL A . n 
A 1 28  GLN 28  29  28  GLN GLN A . n 
A 1 29  THR 29  30  29  THR THR A . n 
A 1 30  VAL 30  31  30  VAL VAL A . n 
A 1 31  VAL 31  32  31  VAL VAL A . n 
A 1 32  PRO 32  33  32  PRO PRO A . n 
A 1 33  ALA 33  34  33  ALA ALA A . n 
A 1 34  PRO 34  35  34  PRO PRO A . n 
A 1 35  PRO 35  36  35  PRO PRO A . n 
A 1 36  GLU 36  37  36  GLU GLU A . n 
A 1 37  ALA 37  38  37  ALA ALA A . n 
A 1 38  ILE 38  39  38  ILE ILE A . n 
A 1 39  THR 39  40  39  THR THR A . n 
A 1 40  VAL 40  41  40  VAL VAL A . n 
A 1 41  MET 41  42  41  MET MET A . n 
A 1 42  MET 42  43  42  MET MET A . n 
A 1 43  HIS 43  44  43  HIS HIS A . n 
A 1 44  GLU 44  45  44  GLU GLU A . n 
A 1 45  MET 45  46  45  MET MET A . n 
A 1 46  GLN 46  47  46  GLN GLN A . n 
A 1 47  ALA 47  48  47  ALA ALA A . n 
A 1 48  ALA 48  49  48  ALA ALA A . n 
A 1 49  ASP 49  50  49  ASP ASP A . n 
A 1 50  TYR 50  51  50  TYR TYR A . n 
A 1 51  MET 51  52  51  MET MET A . n 
A 1 52  ARG 52  53  52  ARG ARG A . n 
A 1 53  GLY 53  54  53  GLY GLY A . n 
A 1 54  ALA 54  55  54  ALA ALA A . n 
A 1 55  THR 55  56  55  THR THR A . n 
A 1 56  ARG 56  57  56  ARG ARG A . n 
A 1 57  ARG 57  58  57  ARG ARG A . n 
A 1 58  THR 58  59  58  THR THR A . n 
A 1 59  PRO 59  60  59  PRO PRO A . n 
A 1 60  ALA 60  61  60  ALA ALA A . n 
A 1 61  PRO 61  62  61  PRO PRO A . n 
A 1 62  ALA 62  63  62  ALA ALA A . n 
A 1 63  LEU 63  64  63  LEU LEU A . n 
A 1 64  PRO 64  65  64  PRO PRO A . n 
A 1 65  ASP 65  66  65  ASP ASP A . n 
A 1 66  ALA 66  67  66  ALA ALA A . n 
A 1 67  ALA 67  68  67  ALA ALA A . n 
A 1 68  ALA 68  69  68  ALA ALA A . n 
A 1 69  THR 69  70  69  THR THR A . n 
A 1 70  VAL 70  71  70  VAL VAL A . n 
A 1 71  ARG 71  72  71  ARG ARG A . n 
A 1 72  ASP 72  73  72  ASP ASP A . n 
A 1 73  PHE 73  74  73  PHE PHE A . n 
A 1 74  LEU 74  75  74  LEU LEU A . n 
A 1 75  ASP 75  76  75  ASP ASP A . n 
A 1 76  THR 76  77  76  THR THR A . n 
A 1 77  MET 77  78  77  MET MET A . n 
A 1 78  GLU 78  79  78  GLU GLU A . n 
A 1 79  ALA 79  80  79  ALA ALA A . n 
A 1 80  ARG 80  81  80  ARG ARG A . n 
A 1 81  ASP 81  82  81  ASP ASP A . n 
A 1 82  LEU 82  83  82  LEU LEU A . n 
A 1 83  ASP 83  84  83  ASP ASP A . n 
A 1 84  LYS 84  85  84  LYS LYS A . n 
A 1 85  ALA 85  86  85  ALA ALA A . n 
A 1 86  ARG 86  87  86  ARG ARG A . n 
A 1 87  THR 87  88  87  THR THR A . n 
A 1 88  PHE 88  89  88  PHE PHE A . n 
A 1 89  LEU 89  90  89  LEU LEU A . n 
A 1 90  THR 90  91  90  THR THR A . n 
A 1 91  ASP 91  92  91  ASP ASP A . n 
A 1 92  ASP 92  93  92  ASP ASP A . n 
A 1 93  PHE 93  94  93  PHE PHE A . n 
A 1 94  VAL 94  95  94  VAL VAL A . n 
A 1 95  MET 95  96  95  MET MET A . n 
A 1 96  THR 96  97  96  THR THR A . n 
A 1 97  PHE 97  98  97  PHE PHE A . n 
A 1 98  PRO 98  99  98  PRO PRO A . n 
A 1 99  THR 99  100 99  THR THR A . n 
A 1 100 GLY 100 101 100 GLY GLY A . n 
A 1 101 ARG 101 102 101 ARG ARG A . n 
A 1 102 ARG 102 103 102 ARG ARG A . n 
A 1 103 MET 103 104 103 MET MET A . n 
A 1 104 THR 104 105 104 THR THR A . n 
A 1 105 ASP 105 106 105 ASP ASP A . n 
A 1 106 LEU 106 107 106 LEU LEU A . n 
A 1 107 SER 107 108 107 SER SER A . n 
A 1 108 ASP 108 109 108 ASP ASP A . n 
A 1 109 LEU 109 110 109 LEU LEU A . n 
A 1 110 VAL 110 111 110 VAL VAL A . n 
A 1 111 GLU 111 112 111 GLU GLU A . n 
A 1 112 TRP 112 113 112 TRP TRP A . n 
A 1 113 SER 113 114 113 SER SER A . n 
A 1 114 ALA 114 115 114 ALA ALA A . n 
A 1 115 THR 115 116 115 THR THR A . n 
A 1 116 ARG 116 117 116 ARG ARG A . n 
A 1 117 TYR 117 118 117 TYR TYR A . n 
A 1 118 ARG 118 119 118 ARG ARG A . n 
A 1 119 PHE 119 120 119 PHE PHE A . n 
A 1 120 VAL 120 121 120 VAL VAL A . n 
A 1 121 THR 121 122 121 THR THR A . n 
A 1 122 LYS 122 123 122 LYS LYS A . n 
A 1 123 THR 123 124 123 THR THR A . n 
A 1 124 TYR 124 125 124 TYR TYR A . n 
A 1 125 ASP 125 126 125 ASP ASP A . n 
A 1 126 ARG 126 127 126 ARG ARG A . n 
A 1 127 PHE 127 128 127 PHE PHE A . n 
A 1 128 ASP 128 129 128 ASP ASP A . n 
A 1 129 THR 129 130 129 THR THR A . n 
A 1 130 ALA 130 131 130 ALA ALA A . n 
A 1 131 ALA 131 132 131 ALA ALA A . n 
A 1 132 THR 132 133 132 THR THR A . n 
A 1 133 LEU 133 134 133 LEU LEU A . n 
A 1 134 ASP 134 135 134 ASP ASP A . n 
A 1 135 GLY 135 136 135 GLY GLY A . n 
A 1 136 PRO 136 137 136 PRO PRO A . n 
A 1 137 VAL 137 138 137 VAL VAL A . n 
A 1 138 VAL 138 139 138 VAL VAL A . n 
A 1 139 TYR 139 140 139 TYR TYR A . n 
A 1 140 CYS 140 141 140 CYS CYS A . n 
A 1 141 PHE 141 142 141 PHE PHE A . n 
A 1 142 GLY 142 143 142 GLY GLY A . n 
A 1 143 THR 143 144 143 THR THR A . n 
A 1 144 LEU 144 145 144 LEU LEU A . n 
A 1 145 ARG 145 146 145 ARG ARG A . n 
A 1 146 GLY 146 147 146 GLY GLY A . n 
A 1 147 GLU 147 148 147 GLU GLU A . n 
A 1 148 TRP 148 149 148 TRP TRP A . n 
A 1 149 PRO 149 150 149 PRO PRO A . n 
A 1 150 ASP 150 151 150 ASP ASP A . n 
A 1 151 GLY 151 152 151 GLY GLY A . n 
A 1 152 THR 152 153 152 THR THR A . n 
A 1 153 PRO 153 154 153 PRO PRO A . n 
A 1 154 PHE 154 155 154 PHE PHE A . n 
A 1 155 ASP 155 156 155 ASP ASP A . n 
A 1 156 ASN 156 157 156 ASN ASN A . n 
A 1 157 VAL 157 158 157 VAL VAL A . n 
A 1 158 ARG 158 159 158 ARG ARG A . n 
A 1 159 PHE 159 160 159 PHE PHE A . n 
A 1 160 ILE 160 161 160 ILE ILE A . n 
A 1 161 ASP 161 162 161 ASP ASP A . n 
A 1 162 ARG 162 163 162 ARG ARG A . n 
A 1 163 PHE 163 164 163 PHE PHE A . n 
A 1 164 ALA 164 165 164 ALA ALA A . n 
A 1 165 LEU 165 166 165 LEU LEU A . n 
A 1 166 ARG 166 167 166 ARG ARG A . n 
A 1 167 ASP 167 168 167 ASP ASP A . n 
A 1 168 GLY 168 169 168 GLY GLY A . n 
A 1 169 LYS 169 170 169 LYS LYS A . n 
A 1 170 LEU 170 171 170 LEU LEU A . n 
A 1 171 ALA 171 172 171 ALA ALA A . n 
A 1 172 VAL 172 173 172 VAL VAL A . n 
A 1 173 GLN 173 174 173 GLN GLN A . n 
A 1 174 ASP 174 175 174 ASP ASP A . n 
A 1 175 VAL 175 176 175 VAL VAL A . n 
A 1 176 TRP 176 177 176 TRP TRP A . n 
A 1 177 ASN 177 178 177 ASN ASN A . n 
A 1 178 ASP 178 179 178 ASP ASP A . n 
A 1 179 LEU 179 180 179 LEU LEU A . n 
A 1 180 GLU 180 181 180 GLU GLU A . n 
A 1 181 ALA 181 182 181 ALA ALA A . n 
A 1 182 MET 182 183 182 MET MET A . n 
A 1 183 ARG 183 184 183 ARG ARG A . n 
A 1 184 PRO 184 185 184 PRO PRO A . n 
A 1 185 ARG 185 186 185 ARG ARG A . n 
A 1 186 GLY 186 187 186 GLY GLY A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ZI0 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ZI0 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HOH 1  201 50  HOH HOH A . 
B 2 HOH 2  202 461 HOH HOH A . 
B 2 HOH 3  203 18  HOH HOH A . 
B 2 HOH 4  204 65  HOH HOH A . 
B 2 HOH 5  205 21  HOH HOH A . 
B 2 HOH 6  206 223 HOH HOH A . 
B 2 HOH 7  207 10  HOH HOH A . 
B 2 HOH 8  208 537 HOH HOH A . 
B 2 HOH 9  209 9   HOH HOH A . 
B 2 HOH 10 210 345 HOH HOH A . 
B 2 HOH 11 211 111 HOH HOH A . 
B 2 HOH 12 212 27  HOH HOH A . 
B 2 HOH 13 213 226 HOH HOH A . 
B 2 HOH 14 214 258 HOH HOH A . 
B 2 HOH 15 215 300 HOH HOH A . 
B 2 HOH 16 216 78  HOH HOH A . 
B 2 HOH 17 217 286 HOH HOH A . 
B 2 HOH 18 218 83  HOH HOH A . 
B 2 HOH 19 219 147 HOH HOH A . 
B 2 HOH 20 220 309 HOH HOH A . 
B 2 HOH 21 221 334 HOH HOH A . 
B 2 HOH 22 222 193 HOH HOH A . 
B 2 HOH 23 223 425 HOH HOH A . 
B 2 HOH 24 224 44  HOH HOH A . 
B 2 HOH 25 225 58  HOH HOH A . 
B 2 HOH 26 226 121 HOH HOH A . 
B 2 HOH 27 227 282 HOH HOH A . 
B 2 HOH 28 228 394 HOH HOH A . 
B 2 HOH 29 229 26  HOH HOH A . 
B 2 HOH 30 230 12  HOH HOH A . 
B 2 HOH 31 231 293 HOH HOH A . 
B 2 HOH 32 232 168 HOH HOH A . 
B 2 HOH 33 233 41  HOH HOH A . 
B 2 HOH 34 234 298 HOH HOH A . 
B 2 HOH 35 235 183 HOH HOH A . 
B 2 HOH 36 236 20  HOH HOH A . 
B 2 HOH 37 237 35  HOH HOH A . 
B 2 HOH 38 238 305 HOH HOH A . 
B 2 HOH 39 239 47  HOH HOH A . 
B 2 HOH 40 240 73  HOH HOH A . 
B 2 HOH 41 241 11  HOH HOH A . 
B 2 HOH 42 242 23  HOH HOH A . 
B 2 HOH 43 243 119 HOH HOH A . 
B 2 HOH 44 244 185 HOH HOH A . 
B 2 HOH 45 245 221 HOH HOH A . 
B 2 HOH 46 246 42  HOH HOH A . 
B 2 HOH 47 247 189 HOH HOH A . 
B 2 HOH 48 248 172 HOH HOH A . 
B 2 HOH 49 249 16  HOH HOH A . 
B 2 HOH 50 250 29  HOH HOH A . 
B 2 HOH 51 251 344 HOH HOH A . 
B 2 HOH 52 252 460 HOH HOH A . 
B 2 HOH 53 253 301 HOH HOH A . 
B 2 HOH 54 254 118 HOH HOH A . 
B 2 HOH 55 255 374 HOH HOH A . 
B 2 HOH 56 256 194 HOH HOH A . 
B 2 HOH 57 257 285 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.21.1_5286 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? autoPROC ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless  ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MUP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     188.389 
_cell.length_a_esd                 ? 
_cell.length_b                     188.389 
_cell.length_b_esd                 ? 
_cell.length_c                     82.646 
_cell.length_c_esd                 ? 
_cell.volume                       2540174.502 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MUP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                182 
_symmetry.space_group_name_Hall            'P 6c 2c' 
_symmetry.space_group_name_H-M             'P 63 2 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MUP 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             10.02 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          87.73 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '9mg/mL protein + 6x molar excess of 3-bromopropiolate, 2 M sodium formate pH 7' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            277 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     80 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-12-03 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             MAD 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.92009 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NSLS-II BEAMLINE 17-ID-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.92009 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   17-ID-1 
_diffrn_source.pdbx_synchrotron_site       NSLS-II 
# 
_reflns.B_iso_Wilson_estimate                          52.41 
_reflns.entry_id                                       9MUP 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.27 
_reflns.d_resolution_low                               34.1 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     40075 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                19.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                .045 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              .196 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.27 
_reflns_shell.d_res_low                                     2.33 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.8 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1960 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               1.182 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  .361 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  5.287 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               64.24 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9MUP 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.27 
_refine.ls_d_res_low                             34.10 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     39939 
_refine.ls_number_reflns_R_free                  1998 
_refine.ls_number_reflns_R_work                  37941 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.65 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2091 
_refine.ls_R_factor_R_free                       0.2233 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2084 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.3816 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3459 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.27 
_refine_hist.d_res_low                        34.10 
_refine_hist.number_atoms_solvent             57 
_refine_hist.number_atoms_total               1539 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1469 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         13 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0122  ? 1516 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.2286  ? 2062 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0609  ? 228  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0127  ? 272  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 19.5547 ? 573  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.27 2.33  . . 137 2593 97.47  . . . . 0.3792 . . . . . . . . . . . 0.3603 
'X-RAY DIFFRACTION' 2.33 2.39  . . 140 2671 99.68  . . . . 0.3518 . . . . . . . . . . . 0.3400 
'X-RAY DIFFRACTION' 2.39 2.46  . . 140 2656 100.00 . . . . 0.3328 . . . . . . . . . . . 0.3389 
'X-RAY DIFFRACTION' 2.46 2.54  . . 141 2672 99.72  . . . . 0.3260 . . . . . . . . . . . 0.3233 
'X-RAY DIFFRACTION' 2.54 2.64  . . 141 2680 99.68  . . . . 0.3082 . . . . . . . . . . . 0.3361 
'X-RAY DIFFRACTION' 2.64 2.74  . . 141 2678 99.68  . . . . 0.2996 . . . . . . . . . . . 0.3322 
'X-RAY DIFFRACTION' 2.74 2.87  . . 141 2690 99.89  . . . . 0.2938 . . . . . . . . . . . 0.3665 
'X-RAY DIFFRACTION' 2.87 3.02  . . 141 2691 99.96  . . . . 0.2757 . . . . . . . . . . . 0.3196 
'X-RAY DIFFRACTION' 3.02 3.21  . . 143 2701 99.75  . . . . 0.2607 . . . . . . . . . . . 0.2680 
'X-RAY DIFFRACTION' 3.21 3.45  . . 143 2710 99.79  . . . . 0.2249 . . . . . . . . . . . 0.2528 
'X-RAY DIFFRACTION' 3.45 3.80  . . 143 2718 99.44  . . . . 0.1934 . . . . . . . . . . . 0.2261 
'X-RAY DIFFRACTION' 3.80 4.35  . . 145 2746 99.93  . . . . 0.1653 . . . . . . . . . . . 0.1695 
'X-RAY DIFFRACTION' 4.35 5.47  . . 147 2788 100.00 . . . . 0.1348 . . . . . . . . . . . 0.1446 
'X-RAY DIFFRACTION' 5.47 34.10 . . 155 2947 99.97  . . . . 0.1671 . . . . . . . . . . . 0.1751 
# 
_struct.entry_id                     9MUP 
_struct.title                        '4OT-SnoaL from P. atlanticus - 3-bromopropiolate treated' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MUP 
_struct_keywords.text            'Tautomerase SnoaL-like Inhibited, UNKNOWN FUNCTION' 
_struct_keywords.pdbx_keywords   'UNKNOWN FUNCTION' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A0A0EFB9_9RHOB 
_struct_ref.pdbx_db_accession          A0A0A0EFB9 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;PIVEIHLLEGYSDAEKERLGRSLTAAVQTVVPAPPEAITVMMHEMQAADYMRGATRRTPAPALPDAAATVRDFLDTMEAR
DLDKARTFLTDDFVMTFPTGRRMTDLSDLVEWSATRYRFVTKTYDRFDTAATLDGPVVYCFGTLRGEWPDGTPFDNVRFI
DRFALRDGKLAVQDVWNDLEAMRPRG
;
_struct_ref.pdbx_align_begin           2 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9MUP 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 186 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A0A0EFB9 
_struct_ref_seq.db_align_beg                  2 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  187 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       187 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 24370 ? 
1 MORE         -159  ? 
1 'SSA (A^2)'  46120 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2,3,4,5,6 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555  x,y,z           1.0000000000  0.0000000000  0.0000000000 0.0000000000   0.0000000000  
1.0000000000  0.0000000000 0.0000000000    0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 2_545  -y,x-y-1,z      -0.5000000000 -0.8660254038 0.0000000000 94.1945000000  0.8660254038  
-0.5000000000 0.0000000000 -163.1496597935 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
3 'crystal symmetry operation' 3_655  -x+y+1,-x,z     -0.5000000000 0.8660254038  0.0000000000 188.3890000000 -0.8660254038 
-0.5000000000 0.0000000000 0.0000000000    0.0000000000 0.0000000000 1.0000000000  0.0000000000  
4 'crystal symmetry operation' 10_555 -y,-x,-z+1/2    0.5000000000  -0.8660254038 0.0000000000 0.0000000000   -0.8660254038 
-0.5000000000 0.0000000000 0.0000000000    0.0000000000 0.0000000000 -1.0000000000 41.3230000000 
5 'crystal symmetry operation' 11_655 -x+y+1,y,-z+1/2 -1.0000000000 0.0000000000  0.0000000000 188.3890000000 0.0000000000  
1.0000000000  0.0000000000 0.0000000000    0.0000000000 0.0000000000 -1.0000000000 41.3230000000 
6 'crystal symmetry operation' 12_545 x,x-y-1,-z+1/2  0.5000000000  0.8660254038  0.0000000000 94.1945000000  0.8660254038  
-0.5000000000 0.0000000000 -163.1496597935 0.0000000000 0.0000000000 -1.0000000000 41.3230000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER A 12  ? THR A 29  ? SER A 13  THR A 30  1 ? 18 
HELX_P HELX_P2 AA2 PRO A 34  ? ILE A 38  ? PRO A 35  ILE A 39  5 ? 5  
HELX_P HELX_P3 AA3 GLN A 46  ? TYR A 50  ? GLN A 47  TYR A 51  5 ? 5  
HELX_P HELX_P4 AA4 ASP A 65  ? ALA A 79  ? ASP A 66  ALA A 80  1 ? 15 
HELX_P HELX_P5 AA5 ASP A 81  ? ARG A 86  ? ASP A 82  ARG A 87  1 ? 6  
HELX_P HELX_P6 AA6 ASP A 105 ? THR A 115 ? ASP A 106 THR A 116 1 ? 11 
HELX_P HELX_P7 AA7 ASP A 178 ? ARG A 183 ? ASP A 179 ARG A 184 1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            covale1 
_struct_conn.conn_type_id                  covale 
_struct_conn.pdbx_leaving_atom_flag        both 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           ZI0 
_struct_conn.ptnr1_label_seq_id            1 
_struct_conn.ptnr1_label_atom_id           C 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           A 
_struct_conn.ptnr2_label_comp_id           ILE 
_struct_conn.ptnr2_label_seq_id            2 
_struct_conn.ptnr2_label_atom_id           N 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            ZI0 
_struct_conn.ptnr1_auth_seq_id             1 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            ILE 
_struct_conn.ptnr2_auth_seq_id             3 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.328 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      ZI0 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       1 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       ZI0 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        1 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                PRO 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        ZI0 
_pdbx_modification_feature.type                               Malonylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 2   ? LEU A 8   ? ILE A 3   LEU A 9   
AA1 2 THR A 39  ? MET A 45  ? THR A 40  MET A 46  
AA2 1 ARG A 101 ? MET A 103 ? ARG A 102 MET A 104 
AA2 2 LEU A 89  ? PHE A 97  ? LEU A 90  PHE A 98  
AA2 3 LYS A 169 ? ASN A 177 ? LYS A 170 ASN A 178 
AA2 4 PRO A 153 ? ARG A 166 ? PRO A 154 ARG A 167 
AA2 5 GLY A 135 ? GLU A 147 ? GLY A 136 GLU A 148 
AA2 6 PHE A 119 ? THR A 132 ? PHE A 120 THR A 133 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 3   ? N VAL A 4   O THR A 39  ? O THR A 40  
AA2 1 2 O MET A 103 ? O MET A 104 N MET A 95  ? N MET A 96  
AA2 2 3 N VAL A 94  ? N VAL A 95  O GLN A 173 ? O GLN A 174 
AA2 3 4 O ALA A 171 ? O ALA A 172 N ALA A 164 ? N ALA A 165 
AA2 4 5 O PHE A 163 ? O PHE A 164 N VAL A 138 ? N VAL A 139 
AA2 5 6 O VAL A 137 ? O VAL A 138 N ALA A 130 ? N ALA A 131 
# 
_pdbx_entry_details.entry_id                   9MUP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 HH22 A ARG 119 ? ? 1_555 OG1 A THR 122 ? ? 8_555 1.60 
2 1 NH2  A ARG 119 ? ? 1_555 OG1 A THR 122 ? ? 8_555 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 66  ? ? -47.41 109.91 
2 1 THR A 100 ? ? 83.51  -4.63  
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    ZI0 
_pdbx_struct_mod_residue.label_seq_id     1 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     ZI0 
_pdbx_struct_mod_residue.auth_seq_id      1 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   PRO 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    A 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     257 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   B 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1  x,y,z         
2  x-y,x,z+1/2   
3  y,-x+y,z+1/2  
4  -y,x-y,z      
5  -x+y,-x,z     
6  x-y,-y,-z     
7  -x,-x+y,-z    
8  -x,-y,z+1/2   
9  y,x,-z        
10 -y,-x,-z+1/2  
11 -x+y,y,-z+1/2 
12 x,x-y,-z+1/2  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
ZI0 O1   O N N 391 
ZI0 C1   C N N 392 
ZI0 O2   O N N 393 
ZI0 C2   C N N 394 
ZI0 C3   C N N 395 
ZI0 O3   O N N 396 
ZI0 N    N N N 397 
ZI0 CD   C N N 398 
ZI0 CG   C N N 399 
ZI0 CB   C N N 400 
ZI0 CA   C N S 401 
ZI0 C    C N N 402 
ZI0 OXT  O N N 403 
ZI0 O    O N N 404 
ZI0 H1   H N N 405 
ZI0 H4   H N N 406 
ZI0 H3   H N N 407 
ZI0 HD2  H N N 408 
ZI0 HD3  H N N 409 
ZI0 HG2  H N N 410 
ZI0 HG3  H N N 411 
ZI0 HB2  H N N 412 
ZI0 HB3  H N N 413 
ZI0 HA   H N N 414 
ZI0 HXT  H N N 415 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
ZI0 O1  C1   sing N N 376 
ZI0 C1  O2   doub N N 377 
ZI0 C1  C2   sing N N 378 
ZI0 C2  C3   sing N N 379 
ZI0 C3  O3   doub N N 380 
ZI0 C3  N    sing N N 381 
ZI0 N   CD   sing N N 382 
ZI0 CD  CG   sing N N 383 
ZI0 CG  CB   sing N N 384 
ZI0 CB  CA   sing N N 385 
ZI0 CA  C    sing N N 386 
ZI0 C   OXT  sing N N 387 
ZI0 C   O    doub N N 388 
ZI0 N   CA   sing N N 389 
ZI0 O1  H1   sing N N 390 
ZI0 C2  H4   sing N N 391 
ZI0 C2  H3   sing N N 392 
ZI0 CD  HD2  sing N N 393 
ZI0 CD  HD3  sing N N 394 
ZI0 CG  HG2  sing N N 395 
ZI0 CG  HG3  sing N N 396 
ZI0 CB  HB2  sing N N 397 
ZI0 CB  HB3  sing N N 398 
ZI0 CA  HA   sing N N 399 
ZI0 OXT HXT  sing N N 400 
# 
_pdbx_audit_support.funding_organization   'Robert A. Welch Foundation' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           F-2125 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   AF-A0A0A0EFB9-F1 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 63 2 2' 
_space_group.name_Hall        'P 6c 2c' 
_space_group.IT_number        182 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9MUP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.005308 
_atom_sites.fract_transf_matrix[1][2]   0.003065 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006129 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012100 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
HETATM 1    O O1   . ZI0 A 1 1   ? 104.39811 -46.83241 25.85579 0.500 75.92435  ? 1   ZI0 A O1   1 
HETATM 2    C C1   . ZI0 A 1 1   ? 104.64028 -45.63197 26.14324 0.500 74.00593  ? 1   ZI0 A C1   1 
HETATM 3    O O2   . ZI0 A 1 1   ? 104.45462 -45.21619 27.34595 0.500 73.61016  ? 1   ZI0 A O2   1 
HETATM 4    C C2   . ZI0 A 1 1   ? 105.13893 -44.74481 24.99664 1.000 65.08421  ? 1   ZI0 A C2   1 
HETATM 5    C C3   . ZI0 A 1 1   ? 105.17451 -43.26391 25.28468 1.000 71.53955  ? 1   ZI0 A C3   1 
HETATM 6    O O3   . ZI0 A 1 1   ? 106.18920 -42.65963 25.45177 1.000 78.47879  ? 1   ZI0 A O3   1 
HETATM 7    N N    . ZI0 A 1 1   ? 103.89462 -42.63068 25.37085 1.000 67.36493  ? 1   ZI0 A N    1 
HETATM 8    C CD   . ZI0 A 1 1   ? 103.65499 -41.38426 25.66009 1.000 58.28508  ? 1   ZI0 A CD   1 
HETATM 9    C CG   . ZI0 A 1 1   ? 102.22171 -41.42022 26.23161 1.000 61.91245  ? 1   ZI0 A CG   1 
HETATM 10   C CB   . ZI0 A 1 1   ? 101.53816 -42.69153 25.59407 1.000 58.41707  ? 1   ZI0 A CB   1 
HETATM 11   C CA   . ZI0 A 1 1   ? 102.52285 -43.45674 25.17210 1.000 58.74723  ? 1   ZI0 A CA   1 
HETATM 12   C C    . ZI0 A 1 1   ? 102.25473 -43.92786 23.73781 1.000 61.70777  ? 1   ZI0 A C    1 
HETATM 13   O O    . ZI0 A 1 1   ? 102.82966 -43.49244 22.77072 1.000 54.92438  ? 1   ZI0 A O    1 
ATOM   14   N N    . ILE A 1 2   ? 101.34204 -44.88899 23.66098 1.000 60.10621  ? 3   ILE A N    1 
ATOM   15   C CA   . ILE A 1 2   ? 100.94760 -45.42769 22.37491 1.000 58.75070  ? 3   ILE A CA   1 
ATOM   16   C C    . ILE A 1 2   ? 99.45861  -45.26718 22.20190 1.000 55.25642  ? 3   ILE A C    1 
ATOM   17   O O    . ILE A 1 2   ? 98.68964  -45.74594 23.04053 1.000 53.41478  ? 3   ILE A O    1 
ATOM   18   C CB   . ILE A 1 2   ? 101.30649 -46.90495 22.23326 1.000 61.44413  ? 3   ILE A CB   1 
ATOM   19   C CG1  . ILE A 1 2   ? 102.82040 -47.05299 22.21944 1.000 62.12377  ? 3   ILE A CG1  1 
ATOM   20   C CG2  . ILE A 1 2   ? 100.67518 -47.49876 20.97636 1.000 57.79673  ? 3   ILE A CG2  1 
ATOM   21   C CD1  . ILE A 1 2   ? 103.24239 -48.48151 22.53678 1.000 66.30892  ? 3   ILE A CD1  1 
ATOM   22   H H    . ILE A 1 2   ? 100.94193 -45.24056 24.33619 1.000 72.19872  ? 3   ILE A H    1 
ATOM   23   H HA   . ILE A 1 2   ? 101.42409 -44.93595 21.68786 1.000 70.57211  ? 3   ILE A HA   1 
ATOM   24   H HB   . ILE A 1 2   ? 100.95156 -47.39475 22.99156 1.000 73.80423  ? 3   ILE A HB   1 
ATOM   25   H HG12 . ILE A 1 2   ? 103.15732 -46.82277 21.33946 1.000 74.61980  ? 3   ILE A HG12 1 
ATOM   26   H HG13 . ILE A 1 2   ? 103.20647 -46.46449 22.88692 1.000 74.61980  ? 3   ILE A HG13 1 
ATOM   27   H HG21 . ILE A 1 2   ? 101.03477 -48.38805 20.83229 1.000 69.42734  ? 3   ILE A HG21 1 
ATOM   28   H HG22 . ILE A 1 2   ? 99.71402  -47.54632 21.09799 1.000 69.42734  ? 3   ILE A HG22 1 
ATOM   29   H HG23 . ILE A 1 2   ? 100.88502 -46.93039 20.21884 1.000 69.42734  ? 3   ILE A HG23 1 
ATOM   30   H HD11 . ILE A 1 2   ? 104.20409 -48.55673 22.43494 1.000 79.64197  ? 3   ILE A HD11 1 
ATOM   31   H HD12 . ILE A 1 2   ? 102.98909 -48.69025 23.44956 1.000 79.64197  ? 3   ILE A HD12 1 
ATOM   32   H HD13 . ILE A 1 2   ? 102.79649 -49.08620 21.92324 1.000 79.64197  ? 3   ILE A HD13 1 
ATOM   33   N N    . VAL A 1 3   ? 99.07011  -44.67436 21.07491 1.000 50.87229  ? 4   VAL A N    1 
ATOM   34   C CA   . VAL A 1 3   ? 97.68200  -44.37478 20.74712 1.000 53.82188  ? 4   VAL A CA   1 
ATOM   35   C C    . VAL A 1 3   ? 97.27737  -45.20136 19.53411 1.000 49.98203  ? 4   VAL A C    1 
ATOM   36   O O    . VAL A 1 3   ? 97.96578  -45.18095 18.51855 1.000 51.03696  ? 4   VAL A O    1 
ATOM   37   C CB   . VAL A 1 3   ? 97.49903  -42.88075 20.43044 1.000 52.91216  ? 4   VAL A CB   1 
ATOM   38   C CG1  . VAL A 1 3   ? 96.04598  -42.55055 20.12223 1.000 50.78989  ? 4   VAL A CG1  1 
ATOM   39   C CG2  . VAL A 1 3   ? 98.02931  -42.06399 21.55165 1.000 49.76732  ? 4   VAL A CG2  1 
ATOM   40   H H    . VAL A 1 3   ? 99.61776  -44.42659 20.45987 1.000 61.11801  ? 4   VAL A H    1 
ATOM   41   H HA   . VAL A 1 3   ? 97.12303  -44.62172 21.50043 1.000 64.65752  ? 4   VAL A HA   1 
ATOM   42   H HB   . VAL A 1 3   ? 98.00195  -42.65882 19.63124 1.000 63.56586  ? 4   VAL A HB   1 
ATOM   43   H HG11 . VAL A 1 3   ? 95.89917  -41.60321 20.27018 1.000 61.01913  ? 4   VAL A HG11 1 
ATOM   44   H HG12 . VAL A 1 3   ? 95.86101  -42.77332 19.19645 1.000 61.01913  ? 4   VAL A HG12 1 
ATOM   45   H HG13 . VAL A 1 3   ? 95.47305  -43.06953 20.70816 1.000 61.01913  ? 4   VAL A HG13 1 
ATOM   46   H HG21 . VAL A 1 3   ? 97.73874  -41.14551 21.43829 1.000 59.79205  ? 4   VAL A HG21 1 
ATOM   47   H HG22 . VAL A 1 3   ? 97.68920  -42.41764 22.38841 1.000 59.79205  ? 4   VAL A HG22 1 
ATOM   48   H HG23 . VAL A 1 3   ? 98.99829  -42.10778 21.54355 1.000 59.79205  ? 4   VAL A HG23 1 
ATOM   49   N N    . GLU A 1 4   ? 96.16945  -45.92371 19.63413 1.000 52.21952  ? 5   GLU A N    1 
ATOM   50   C CA   . GLU A 1 4   ? 95.54441  -46.57799 18.49315 1.000 53.93101  ? 5   GLU A CA   1 
ATOM   51   C C    . GLU A 1 4   ? 94.22562  -45.87733 18.23490 1.000 52.64368  ? 5   GLU A C    1 
ATOM   52   O O    . GLU A 1 4   ? 93.56013  -45.44914 19.17124 1.000 51.37115  ? 5   GLU A O    1 
ATOM   53   C CB   . GLU A 1 4   ? 95.29161  -48.06305 18.74329 1.000 58.19946  ? 5   GLU A CB   1 
ATOM   54   C CG   . GLU A 1 4   ? 96.51076  -48.85431 19.23953 1.000 73.00981  ? 5   GLU A CG   1 
ATOM   55   C CD   . GLU A 1 4   ? 96.21066  -50.35107 19.48284 1.000 83.52809  ? 5   GLU A CD   1 
ATOM   56   O OE1  . GLU A 1 4   ? 95.57291  -50.98885 18.59274 1.000 79.47435  ? 5   GLU A OE1  1 
ATOM   57   O OE2  . GLU A 1 4   ? 96.62173  -50.87505 20.55223 1.000 82.03573  ? 5   GLU A OE2  1 
ATOM   58   H H    . GLU A 1 4   ? 95.74959  -46.05289 20.37347 1.000 62.73468  ? 5   GLU A H    1 
ATOM   59   H HA   . GLU A 1 4   ? 96.12255  -46.51824 17.71656 1.000 64.78848  ? 5   GLU A HA   1 
ATOM   60   H HB2  . GLU A 1 4   ? 94.59707  -48.14731 19.41516 1.000 69.91062  ? 5   GLU A HB2  1 
ATOM   61   H HB3  . GLU A 1 4   ? 95.00006  -48.46910 17.91201 1.000 69.91062  ? 5   GLU A HB3  1 
ATOM   62   H HG2  . GLU A 1 4   ? 97.21467  -48.79616 18.57467 1.000 87.68304  ? 5   GLU A HG2  1 
ATOM   63   H HG3  . GLU A 1 4   ? 96.81364  -48.47142 20.07771 1.000 87.68304  ? 5   GLU A HG3  1 
ATOM   64   N N    . ILE A 1 5   ? 93.84476  -45.72979 16.97447 1.000 53.26501  ? 6   ILE A N    1 
ATOM   65   C CA   . ILE A 1 5   ? 92.50989  -45.23609 16.67217 1.000 56.99043  ? 6   ILE A CA   1 
ATOM   66   C C    . ILE A 1 5   ? 91.89036  -46.08243 15.56538 1.000 56.13924  ? 6   ILE A C    1 
ATOM   67   O O    . ILE A 1 5   ? 92.54269  -46.40405 14.57259 1.000 53.49320  ? 6   ILE A O    1 
ATOM   68   C CB   . ILE A 1 5   ? 92.50870  -43.73972 16.29711 1.000 50.18286  ? 6   ILE A CB   1 
ATOM   69   C CG1  . ILE A 1 5   ? 91.06552  -43.31191 15.94795 1.000 53.57854  ? 6   ILE A CG1  1 
ATOM   70   C CG2  . ILE A 1 5   ? 93.38602  -43.46961 15.12389 1.000 53.19742  ? 6   ILE A CG2  1 
ATOM   71   C CD1  . ILE A 1 5   ? 90.88557  -41.83232 15.88002 1.000 51.84490  ? 6   ILE A CD1  1 
ATOM   72   H H    . ILE A 1 5   ? 94.33362  -45.90607 16.28924 1.000 63.98927  ? 6   ILE A H    1 
ATOM   73   H HA   . ILE A 1 5   ? 91.95927  -45.34307 17.46354 1.000 68.45978  ? 6   ILE A HA   1 
ATOM   74   H HB   . ILE A 1 5   ? 92.84648  -43.23902 17.05613 1.000 60.29069  ? 6   ILE A HB   1 
ATOM   75   H HG12 . ILE A 1 5   ? 90.83055  -43.68023 15.08191 1.000 64.36552  ? 6   ILE A HG12 1 
ATOM   76   H HG13 . ILE A 1 5   ? 90.46430  -43.65379 16.62806 1.000 64.36552  ? 6   ILE A HG13 1 
ATOM   77   H HG21 . ILE A 1 5   ? 93.45485  -42.51066 14.99516 1.000 63.90817  ? 6   ILE A HG21 1 
ATOM   78   H HG22 . ILE A 1 5   ? 94.26444  -43.84449 15.29348 1.000 63.90817  ? 6   ILE A HG22 1 
ATOM   79   H HG23 . ILE A 1 5   ? 92.99674  -43.88190 14.33689 1.000 63.90817  ? 6   ILE A HG23 1 
ATOM   80   H HD11 . ILE A 1 5   ? 89.93832  -41.63175 15.82173 1.000 62.28515  ? 6   ILE A HD11 1 
ATOM   81   H HD12 . ILE A 1 5   ? 91.25991  -41.43160 16.68013 1.000 62.28515  ? 6   ILE A HD12 1 
ATOM   82   H HD13 . ILE A 1 5   ? 91.34420  -41.49412 15.09505 1.000 62.28515  ? 6   ILE A HD13 1 
ATOM   83   N N    . HIS A 1 6   ? 90.62691  -46.42945 15.74233 1.000 53.78832  ? 7   HIS A N    1 
ATOM   84   C CA   . HIS A 1 6   ? 89.88252  -47.26695 14.82755 1.000 55.24586  ? 7   HIS A CA   1 
ATOM   85   C C    . HIS A 1 6   ? 88.89174  -46.40759 14.06701 1.000 55.75903  ? 7   HIS A C    1 
ATOM   86   O O    . HIS A 1 6   ? 88.09179  -45.69237 14.68013 1.000 60.98464  ? 7   HIS A O    1 
ATOM   87   C CB   . HIS A 1 6   ? 89.14975  -48.37054 15.59368 1.000 62.65326  ? 7   HIS A CB   1 
ATOM   88   C CG   . HIS A 1 6   ? 90.06623  -49.29509 16.34084 1.000 68.27896  ? 7   HIS A CG   1 
ATOM   89   N ND1  . HIS A 1 6   ? 90.45753  -49.06792 17.64831 1.000 68.69050  ? 7   HIS A ND1  1 
ATOM   90   C CD2  . HIS A 1 6   ? 90.64277  -50.46239 15.97501 1.000 67.00965  ? 7   HIS A CD2  1 
ATOM   91   C CE1  . HIS A 1 6   ? 91.25508  -50.04337 18.04084 1.000 72.54736  ? 7   HIS A CE1  1 
ATOM   92   N NE2  . HIS A 1 6   ? 91.37934  -50.90434 17.04568 1.000 76.98776  ? 7   HIS A NE2  1 
ATOM   93   H H    . HIS A 1 6   ? 90.15912  -46.17835 16.41889 1.000 64.61725  ? 7   HIS A H    1 
ATOM   94   H HA   . HIS A 1 6   ? 90.48270  -47.68113 14.18791 1.000 66.36630  ? 7   HIS A HA   1 
ATOM   95   H HB2  . HIS A 1 6   ? 88.55289  -47.95965 16.23853 1.000 75.25518  ? 7   HIS A HB2  1 
ATOM   96   H HB3  . HIS A 1 6   ? 88.64068  -48.90344 14.96300 1.000 75.25518  ? 7   HIS A HB3  1 
ATOM   97   H HD2  . HIS A 1 6   ? 90.55637  -50.88646 15.15185 1.000 80.48284  ? 7   HIS A HD2  1 
ATOM   98   H HE1  . HIS A 1 6   ? 91.66036  -50.11305 18.87498 1.000 87.12810  ? 7   HIS A HE1  1 
ATOM   99   H HE2  . HIS A 1 6   ? 91.84682  -51.62591 17.06577 1.000 92.45657  ? 7   HIS A HE2  1 
ATOM   100  N N    . LEU A 1 7   ? 88.94207  -46.47570 12.73688 1.000 59.85468  ? 8   LEU A N    1 
ATOM   101  C CA   . LEU A 1 7   ? 88.14085  -45.56910 11.92083 1.000 68.09076  ? 8   LEU A CA   1 
ATOM   102  C C    . LEU A 1 7   ? 87.75626  -46.29658 10.63560 1.000 66.05996  ? 8   LEU A C    1 
ATOM   103  O O    . LEU A 1 7   ? 88.38069  -47.29463 10.24076 1.000 59.86718  ? 8   LEU A O    1 
ATOM   104  C CB   . LEU A 1 7   ? 88.89375  -44.25413 11.69512 1.000 60.07104  ? 8   LEU A CB   1 
ATOM   105  C CG   . LEU A 1 7   ? 90.35864  -44.47149 11.31158 1.000 69.28282  ? 8   LEU A CG   1 
ATOM   106  C CD1  . LEU A 1 7   ? 90.46126  -45.13159 9.93264  1.000 86.66053  ? 8   LEU A CD1  1 
ATOM   107  C CD2  . LEU A 1 7   ? 91.06284  -43.12626 11.34505 1.000 59.45260  ? 8   LEU A CD2  1 
ATOM   108  H H    . LEU A 1 7   ? 89.42547  -47.03025 12.29147 1.000 71.89688  ? 8   LEU A H    1 
ATOM   109  H HA   . LEU A 1 7   ? 87.30317  -45.33531 12.35040 1.000 81.78018  ? 8   LEU A HA   1 
ATOM   110  H HB2  . LEU A 1 7   ? 88.46380  -43.76384 10.97702 1.000 72.15652  ? 8   LEU A HB2  1 
ATOM   111  H HB3  . LEU A 1 7   ? 88.87050  -43.73306 12.51295 1.000 72.15652  ? 8   LEU A HB3  1 
ATOM   112  H HG   . LEU A 1 7   ? 90.79577  -45.07054 11.93685 1.000 83.21065  ? 8   LEU A HG   1 
ATOM   113  H HD11 . LEU A 1 7   ? 91.06525  -44.61299 9.37842  1.000 104.06390 ? 8   LEU A HD11 1 
ATOM   114  H HD12 . LEU A 1 7   ? 90.80196  -46.03356 10.03886 1.000 104.06390 ? 8   LEU A HD12 1 
ATOM   115  H HD13 . LEU A 1 7   ? 89.58003  -45.15638 9.52802  1.000 104.06390 ? 8   LEU A HD13 1 
ATOM   116  H HD21 . LEU A 1 7   ? 92.00070  -43.25541 11.13378 1.000 71.41438  ? 8   LEU A HD21 1 
ATOM   117  H HD22 . LEU A 1 7   ? 90.65395  -42.53938 10.68986 1.000 71.41438  ? 8   LEU A HD22 1 
ATOM   118  H HD23 . LEU A 1 7   ? 90.97314  -42.74485 12.23239 1.000 71.41438  ? 8   LEU A HD23 1 
ATOM   119  N N    . LEU A 1 8   ? 86.70241  -45.80987 9.99432  1.000 68.00177  ? 9   LEU A N    1 
ATOM   120  C CA   . LEU A 1 8   ? 86.30408  -46.39296 8.71313  1.000 69.59902  ? 9   LEU A CA   1 
ATOM   121  C C    . LEU A 1 8   ? 87.19891  -45.89701 7.58191  1.000 64.43237  ? 9   LEU A C    1 
ATOM   122  O O    . LEU A 1 8   ? 87.73178  -44.77845 7.62137  1.000 60.48186  ? 9   LEU A O    1 
ATOM   123  C CB   . LEU A 1 8   ? 84.85402  -46.06193 8.40392  1.000 67.26072  ? 9   LEU A CB   1 
ATOM   124  C CG   . LEU A 1 8   ? 83.86177  -46.78837 9.30871  1.000 70.42629  ? 9   LEU A CG   1 
ATOM   125  C CD1  . LEU A 1 8   ? 82.52934  -46.06686 9.37307  1.000 99.95349  ? 9   LEU A CD1  1 
ATOM   126  C CD2  . LEU A 1 8   ? 83.65611  -48.21156 8.81103  1.000 75.23731  ? 9   LEU A CD2  1 
ATOM   127  H H    . LEU A 1 8   ? 86.21176  -45.15946 10.26969 1.000 81.67339  ? 9   LEU A H    1 
ATOM   128  H HA   . LEU A 1 8   ? 86.39280  -47.35757 8.76386  1.000 83.59009  ? 9   LEU A HA   1 
ATOM   129  H HB2  . LEU A 1 8   ? 84.71962  -45.10814 8.51847  1.000 80.78413  ? 9   LEU A HB2  1 
ATOM   130  H HB3  . LEU A 1 8   ? 84.66373  -46.31607 7.48735  1.000 80.78413  ? 9   LEU A HB3  1 
ATOM   131  H HG   . LEU A 1 8   ? 84.22533  -46.80985 10.20774 1.000 84.58281  ? 9   LEU A HG   1 
ATOM   132  H HD11 . LEU A 1 8   ? 81.92785  -46.56516 9.94823  1.000 120.01546 ? 9   LEU A HD11 1 
ATOM   133  H HD12 . LEU A 1 8   ? 82.66919  -45.17685 9.73254  1.000 120.01546 ? 9   LEU A HD12 1 
ATOM   134  H HD13 . LEU A 1 8   ? 82.15863  -46.00787 8.47865  1.000 120.01546 ? 9   LEU A HD13 1 
ATOM   135  H HD21 . LEU A 1 8   ? 83.03230  -48.66485 9.39950  1.000 90.35604  ? 9   LEU A HD21 1 
ATOM   136  H HD22 . LEU A 1 8   ? 83.29894  -48.18240 7.90965  1.000 90.35604  ? 9   LEU A HD22 1 
ATOM   137  H HD23 . LEU A 1 8   ? 84.50903  -48.67354 8.81408  1.000 90.35604  ? 9   LEU A HD23 1 
ATOM   138  N N    . GLU A 1 9   ? 87.38001  -46.75616 6.57732  1.000 70.40322  ? 10  GLU A N    1 
ATOM   139  C CA   . GLU A 1 9   ? 88.14167  -46.37692 5.38991  1.000 73.14383  ? 10  GLU A CA   1 
ATOM   140  C C    . GLU A 1 9   ? 87.49113  -45.18090 4.69586  1.000 68.35075  ? 10  GLU A C    1 
ATOM   141  O O    . GLU A 1 9   ? 86.27020  -44.97377 4.76655  1.000 55.97986  ? 10  GLU A O    1 
ATOM   142  C CB   . GLU A 1 9   ? 88.23429  -47.54694 4.40572  1.000 73.21598  ? 10  GLU A CB   1 
ATOM   143  C CG   . GLU A 1 9   ? 86.85782  -48.00890 3.91801  1.000 78.90445  ? 10  GLU A CG   1 
ATOM   144  C CD   . GLU A 1 9   ? 86.93738  -49.06075 2.79467  1.000 90.30445  ? 10  GLU A CD   1 
ATOM   145  O OE1  . GLU A 1 9   ? 88.04998  -49.24481 2.21521  1.000 96.08415  ? 10  GLU A OE1  1 
ATOM   146  O OE2  . GLU A 1 9   ? 85.87970  -49.70099 2.51017  1.000 91.30398  ? 10  GLU A OE2  1 
ATOM   147  H H    . GLU A 1 9   ? 87.07372  -47.55958 6.55963  1.000 84.55514  ? 10  GLU A H    1 
ATOM   148  H HA   . GLU A 1 9   ? 89.04132  -46.13357 5.65882  1.000 87.84387  ? 10  GLU A HA   1 
ATOM   149  H HB2  . GLU A 1 9   ? 88.75159  -47.27111 3.63292  1.000 87.93044  ? 10  GLU A HB2  1 
ATOM   150  H HB3  . GLU A 1 9   ? 88.66664  -48.29654 4.84398  1.000 87.93044  ? 10  GLU A HB3  1 
ATOM   151  H HG2  . GLU A 1 9   ? 86.37580  -48.40246 4.66210  1.000 94.75661  ? 10  GLU A HG2  1 
ATOM   152  H HG3  . GLU A 1 9   ? 86.37144  -47.24261 3.57576  1.000 94.75661  ? 10  GLU A HG3  1 
ATOM   153  N N    . GLY A 1 10  ? 88.33129  -44.39507 4.02026  1.000 61.87650  ? 11  GLY A N    1 
ATOM   154  C CA   . GLY A 1 10  ? 87.86623  -43.27149 3.22680  1.000 58.34149  ? 11  GLY A CA   1 
ATOM   155  C C    . GLY A 1 10  ? 88.54848  -41.95059 3.52879  1.000 66.30472  ? 11  GLY A C    1 
ATOM   156  O O    . GLY A 1 10  ? 88.17845  -40.92514 2.95215  1.000 69.47294  ? 11  GLY A O    1 
ATOM   157  H H    . GLY A 1 10  ? 89.18508  -44.49751 4.00861  1.000 74.32307  ? 11  GLY A H    1 
ATOM   158  H HA2  . GLY A 1 10  ? 88.01231  -43.47142 2.28894  1.000 70.08106  ? 11  GLY A HA2  1 
ATOM   159  H HA3  . GLY A 1 10  ? 86.91565  -43.15453 3.38043  1.000 70.08106  ? 11  GLY A HA3  1 
ATOM   160  N N    . TYR A 1 11  ? 89.50878  -41.93050 4.44628  1.000 60.51309  ? 12  TYR A N    1 
ATOM   161  C CA   . TYR A 1 11  ? 90.22864  -40.70151 4.73971  1.000 58.85959  ? 12  TYR A CA   1 
ATOM   162  C C    . TYR A 1 11  ? 91.51935  -40.69469 3.92683  1.000 56.75966  ? 12  TYR A C    1 
ATOM   163  O O    . TYR A 1 11  ? 92.13312  -41.73897 3.67008  1.000 50.20405  ? 12  TYR A O    1 
ATOM   164  C CB   . TYR A 1 11  ? 90.49402  -40.54932 6.25428  1.000 59.21692  ? 12  TYR A CB   1 
ATOM   165  C CG   . TYR A 1 11  ? 89.19664  -40.43978 7.05111  1.000 59.09415  ? 12  TYR A CG   1 
ATOM   166  C CD1  . TYR A 1 11  ? 88.40214  -39.30206 6.95728  1.000 60.93457  ? 12  TYR A CD1  1 
ATOM   167  C CD2  . TYR A 1 11  ? 88.74417  -41.49129 7.85574  1.000 59.97450  ? 12  TYR A CD2  1 
ATOM   168  C CE1  . TYR A 1 11  ? 87.20410  -39.18981 7.64830  1.000 65.17008  ? 12  TYR A CE1  1 
ATOM   169  C CE2  . TYR A 1 11  ? 87.51691  -41.39229 8.55929  1.000 61.42020  ? 12  TYR A CE2  1 
ATOM   170  C CZ   . TYR A 1 11  ? 86.75899  -40.22374 8.44508  1.000 65.01002  ? 12  TYR A CZ   1 
ATOM   171  O OH   . TYR A 1 11  ? 85.56336  -40.05148 9.08368  1.000 62.56438  ? 12  TYR A OH   1 
ATOM   172  H H    . TYR A 1 11  ? 89.75804  -42.61218 4.90756  1.000 72.68697  ? 12  TYR A H    1 
ATOM   173  H HA   . TYR A 1 11  ? 89.70715  -39.92307 4.48875  1.000 70.70277  ? 12  TYR A HA   1 
ATOM   174  H HB2  . TYR A 1 11  ? 90.98154  -41.32525 6.57234  1.000 71.13157  ? 12  TYR A HB2  1 
ATOM   175  H HB3  . TYR A 1 11  ? 91.01394  -39.74496 6.40786  1.000 71.13157  ? 12  TYR A HB3  1 
ATOM   176  H HD1  . TYR A 1 11  ? 88.68113  -38.59816 6.41729  1.000 73.19275  ? 12  TYR A HD1  1 
ATOM   177  H HD2  . TYR A 1 11  ? 89.25481  -42.26499 7.93008  1.000 72.04066  ? 12  TYR A HD2  1 
ATOM   178  H HE1  . TYR A 1 11  ? 86.69839  -38.41290 7.57371  1.000 78.27536  ? 12  TYR A HE1  1 
ATOM   179  H HE2  . TYR A 1 11  ? 87.22020  -42.09605 9.08994  1.000 73.77551  ? 12  TYR A HE2  1 
ATOM   180  H HH   . TYR A 1 11  ? 85.26761  -40.79310 9.34472  1.000 75.14853  ? 12  TYR A HH   1 
ATOM   181  N N    . SER A 1 12  ? 91.91228  -39.50259 3.50599  1.000 56.22430  ? 13  SER A N    1 
ATOM   182  C CA   . SER A 1 12  ? 93.09982  -39.35040 2.68683  1.000 59.08466  ? 13  SER A CA   1 
ATOM   183  C C    . SER A 1 12  ? 94.35079  -39.50549 3.54405  1.000 55.56213  ? 13  SER A C    1 
ATOM   184  O O    . SER A 1 12  ? 94.29539  -39.44600 4.77137  1.000 60.86734  ? 13  SER A O    1 
ATOM   185  C CB   . SER A 1 12  ? 93.07809  -37.98351 1.99216  1.000 57.26758  ? 13  SER A CB   1 
ATOM   186  O OG   . SER A 1 12  ? 93.15900  -36.92318 2.93940  1.000 59.25283  ? 13  SER A OG   1 
ATOM   187  H H    . SER A 1 12  ? 91.50666  -38.76501 3.68221  1.000 67.54043  ? 13  SER A H    1 
ATOM   188  H HA   . SER A 1 12  ? 93.12157  -40.03687 2.00187  1.000 70.97285  ? 13  SER A HA   1 
ATOM   189  H HB2  . SER A 1 12  ? 93.83588  -37.92512 1.38946  1.000 68.79236  ? 13  SER A HB2  1 
ATOM   190  H HB3  . SER A 1 12  ? 92.25039  -37.89732 1.49377  1.000 68.79236  ? 13  SER A HB3  1 
ATOM   191  H HG   . SER A 1 12  ? 93.92454  -36.57799 2.91954  1.000 71.17466  ? 13  SER A HG   1 
ATOM   192  N N    . ASP A 1 13  ? 95.49943  -39.65448 2.87900  1.000 51.92146  ? 14  ASP A N    1 
ATOM   193  C CA   . ASP A 1 13  ? 96.76753  -39.63998 3.59449  1.000 62.39437  ? 14  ASP A CA   1 
ATOM   194  C C    . ASP A 1 13  ? 96.98280  -38.31445 4.30692  1.000 64.76488  ? 14  ASP A C    1 
ATOM   195  O O    . ASP A 1 13  ? 97.57340  -38.28152 5.39770  1.000 63.30572  ? 14  ASP A O    1 
ATOM   196  C CB   . ASP A 1 13  ? 97.92226  -39.92910 2.64910  1.000 63.32480  ? 14  ASP A CB   1 
ATOM   197  C CG   . ASP A 1 13  ? 97.88521  -41.34880 2.11140  1.000 69.43622  ? 14  ASP A CG   1 
ATOM   198  O OD1  . ASP A 1 13  ? 96.90851  -42.08551 2.44270  1.000 62.49421  ? 14  ASP A OD1  1 
ATOM   199  O OD2  . ASP A 1 13  ? 98.81388  -41.72595 1.36645  1.000 76.61640  ? 14  ASP A OD2  1 
ATOM   200  H H    . ASP A 1 13  ? 95.56703  -39.76340 2.02861  1.000 62.37701  ? 14  ASP A H    1 
ATOM   201  H HA   . ASP A 1 13  ? 96.75523  -40.34592 4.25962  1.000 74.94451  ? 14  ASP A HA   1 
ATOM   202  H HB2  . ASP A 1 13  ? 97.87653  -39.31971 1.89581  1.000 76.06103  ? 14  ASP A HB2  1 
ATOM   203  H HB3  . ASP A 1 13  ? 98.75954  -39.80778 3.12361  1.000 76.06103  ? 14  ASP A HB3  1 
ATOM   204  N N    . ALA A 1 14  ? 96.46607  -37.22599 3.74488  1.000 64.98904  ? 15  ALA A N    1 
ATOM   205  C CA   . ALA A 1 14  ? 96.65288  -35.93325 4.38406  1.000 64.26118  ? 15  ALA A CA   1 
ATOM   206  C C    . ALA A 1 14  ? 95.70521  -35.74619 5.55751  1.000 60.86046  ? 15  ALA A C    1 
ATOM   207  O O    . ALA A 1 14  ? 96.06120  -35.08553 6.54078  1.000 52.79271  ? 15  ALA A O    1 
ATOM   208  C CB   . ALA A 1 14  ? 96.43339  -34.78559 3.39916  1.000 53.48744  ? 15  ALA A CB   1 
ATOM   209  H H    . ALA A 1 14  ? 96.01516  -37.21110 3.01272  1.000 78.05811  ? 15  ALA A H    1 
ATOM   210  H HA   . ALA A 1 14  ? 97.57116  -35.89988 4.69477  1.000 77.18468  ? 15  ALA A HA   1 
ATOM   211  H HB1  . ALA A 1 14  ? 96.64477  -33.94725 3.83894  1.000 64.25620  ? 15  ALA A HB1  1 
ATOM   212  H HB2  . ALA A 1 14  ? 97.01361  -34.91229 2.63222  1.000 64.25620  ? 15  ALA A HB2  1 
ATOM   213  H HB3  . ALA A 1 14  ? 95.50572  -34.78573 3.11573  1.000 64.25620  ? 15  ALA A HB3  1 
ATOM   214  N N    . GLU A 1 15  ? 94.47327  -36.25568 5.45265  1.000 59.03017  ? 16  GLU A N    1 
ATOM   215  C CA   . GLU A 1 15  ? 93.56659  -36.19655 6.59880  1.000 58.03483  ? 16  GLU A CA   1 
ATOM   216  C C    . GLU A 1 15  ? 94.11348  -37.02378 7.76254  1.000 59.25743  ? 16  GLU A C    1 
ATOM   217  O O    . GLU A 1 15  ? 93.98559  -36.63523 8.93010  1.000 53.68683  ? 16  GLU A O    1 
ATOM   218  C CB   . GLU A 1 15  ? 92.16023  -36.66457 6.20030  1.000 52.16913  ? 16  GLU A CB   1 
ATOM   219  C CG   . GLU A 1 15  ? 91.45834  -35.65905 5.30593  1.000 63.47684  ? 16  GLU A CG   1 
ATOM   220  C CD   . GLU A 1 15  ? 90.37401  -36.22692 4.36945  1.000 65.22106  ? 16  GLU A CD   1 
ATOM   221  O OE1  . GLU A 1 15  ? 90.11877  -37.45738 4.31308  1.000 63.07982  ? 16  GLU A OE1  1 
ATOM   222  O OE2  . GLU A 1 15  ? 89.75634  -35.38531 3.68238  1.000 68.39589  ? 16  GLU A OE2  1 
ATOM   223  H H    . GLU A 1 15  ? 94.14869  -36.62963 4.74950  1.000 70.90747  ? 16  GLU A H    1 
ATOM   224  H HA   . GLU A 1 15  ? 93.48743  -35.27526 6.89182  1.000 69.71306  ? 16  GLU A HA   1 
ATOM   225  H HB2  . GLU A 1 15  ? 92.22836  -37.50372 5.71854  1.000 62.67422  ? 16  GLU A HB2  1 
ATOM   226  H HB3  . GLU A 1 15  ? 91.62553  -36.78404 7.00076  1.000 62.67422  ? 16  GLU A HB3  1 
ATOM   227  H HG2  . GLU A 1 15  ? 91.02978  -34.99753 5.87129  1.000 76.24347  ? 16  GLU A HG2  1 
ATOM   228  H HG3  . GLU A 1 15  ? 92.12601  -35.23384 4.74530  1.000 76.24347  ? 16  GLU A HG3  1 
ATOM   229  N N    . LYS A 1 16  ? 94.77219  -38.13936 7.45494  1.000 57.47858  ? 17  LYS A N    1 
ATOM   230  C CA   . LYS A 1 16  ? 95.33590  -38.98345 8.48763  1.000 51.52295  ? 17  LYS A CA   1 
ATOM   231  C C    . LYS A 1 16  ? 96.51486  -38.30054 9.15097  1.000 59.22188  ? 17  LYS A C    1 
ATOM   232  O O    . LYS A 1 16  ? 96.69423  -38.39928 10.37820 1.000 54.83726  ? 17  LYS A O    1 
ATOM   233  C CB   . LYS A 1 16  ? 95.75515  -40.33031 7.89822  1.000 55.11284  ? 17  LYS A CB   1 
ATOM   234  C CG   . LYS A 1 16  ? 94.57890  -41.24125 7.56503  1.000 53.65612  ? 17  LYS A CG   1 
ATOM   235  C CD   . LYS A 1 16  ? 95.05037  -42.52806 6.84508  1.000 63.68286  ? 17  LYS A CD   1 
ATOM   236  C CE   . LYS A 1 16  ? 93.87520  -43.40616 6.41455  1.000 59.41239  ? 17  LYS A CE   1 
ATOM   237  N NZ   . LYS A 1 16  ? 94.34141  -44.65137 5.73166  1.000 73.19291  ? 17  LYS A NZ   1 
ATOM   238  H H    . LYS A 1 16  ? 94.90375  -38.42525 6.65459  1.000 69.04557  ? 17  LYS A H    1 
ATOM   239  H HA   . LYS A 1 16  ? 94.66029  -39.15463 9.16227  1.000 61.89881  ? 17  LYS A HA   1 
ATOM   240  H HB2  . LYS A 1 16  ? 96.25025  -40.17269 7.07912  1.000 66.20667  ? 17  LYS A HB2  1 
ATOM   241  H HB3  . LYS A 1 16  ? 96.31580  -40.79208 8.54113  1.000 66.20667  ? 17  LYS A HB3  1 
ATOM   242  H HG2  . LYS A 1 16  ? 94.12768  -41.49738 8.38460  1.000 64.45860  ? 17  LYS A HG2  1 
ATOM   243  H HG3  . LYS A 1 16  ? 93.96357  -40.77182 6.98030  1.000 64.45860  ? 17  LYS A HG3  1 
ATOM   244  H HD2  . LYS A 1 16  ? 95.55293  -42.28453 6.05197  1.000 76.49070  ? 17  LYS A HD2  1 
ATOM   245  H HD3  . LYS A 1 16  ? 95.60953  -43.04411 7.44669  1.000 76.49070  ? 17  LYS A HD3  1 
ATOM   246  H HE2  . LYS A 1 16  ? 93.36187  -43.66155 7.19696  1.000 71.36613  ? 17  LYS A HE2  1 
ATOM   247  H HE3  . LYS A 1 16  ? 93.31437  -42.91146 5.79677  1.000 71.36613  ? 17  LYS A HE3  1 
ATOM   248  H HZ1  . LYS A 1 16  ? 93.65526  -45.05596 5.33468  1.000 87.90276  ? 17  LYS A HZ1  1 
ATOM   249  H HZ2  . LYS A 1 16  ? 94.95324  -44.45074 5.11724  1.000 87.90276  ? 17  LYS A HZ2  1 
ATOM   250  H HZ3  . LYS A 1 16  ? 94.70058  -45.20816 6.32587  1.000 87.90276  ? 17  LYS A HZ3  1 
ATOM   251  N N    . GLU A 1 17  ? 97.33929  -37.61090 8.36433  1.000 57.48103  ? 18  GLU A N    1 
ATOM   252  C CA   . GLU A 1 17  ? 98.49577  -36.92129 8.93445  1.000 61.86763  ? 18  GLU A CA   1 
ATOM   253  C C    . GLU A 1 17  ? 98.04494  -35.85049 9.92224  1.000 62.43598  ? 18  GLU A C    1 
ATOM   254  O O    . GLU A 1 17  ? 98.58609  -35.74367 11.03681 1.000 55.61003  ? 18  GLU A O    1 
ATOM   255  C CB   . GLU A 1 17  ? 99.33497  -36.34702 7.79479  1.000 65.08664  ? 18  GLU A CB   1 
ATOM   256  C CG   . GLU A 1 17  ? 100.77335 -36.09478 8.09512  1.000 91.88285  ? 18  GLU A CG   1 
ATOM   257  C CD   . GLU A 1 17  ? 100.97120 -34.69297 8.61670  1.000 103.89726 ? 18  GLU A CD   1 
ATOM   258  O OE1  . GLU A 1 17  ? 101.95023 -34.46263 9.37135  1.000 99.16557  ? 18  GLU A OE1  1 
ATOM   259  O OE2  . GLU A 1 17  ? 100.14101 -33.81580 8.27232  1.000 103.68699 ? 18  GLU A OE2  1 
ATOM   260  H H    . GLU A 1 17  ? 97.25419  -37.52724 7.51265  1.000 69.04850  ? 18  GLU A H    1 
ATOM   261  H HA   . GLU A 1 17  ? 99.05860  -37.53874 9.42728  1.000 74.31242  ? 18  GLU A HA   1 
ATOM   262  H HB2  . GLU A 1 17  ? 99.30379  -36.97111 7.05287  1.000 78.17524  ? 18  GLU A HB2  1 
ATOM   263  H HB3  . GLU A 1 17  ? 98.94569  -35.49857 7.53119  1.000 78.17524  ? 18  GLU A HB3  1 
ATOM   264  H HG2  . GLU A 1 17  ? 101.07806 -36.72114 8.77020  1.000 110.33068 ? 18  GLU A HG2  1 
ATOM   265  H HG3  . GLU A 1 17  ? 101.29666 -36.19944 7.28512  1.000 110.33068 ? 18  GLU A HG3  1 
ATOM   266  N N    . ARG A 1 18  ? 97.00556  -35.09951 9.56015  1.000 55.25840  ? 19  ARG A N    1 
ATOM   267  C CA   . ARG A 1 18  ? 96.41937  -34.13976 10.49347 1.000 59.72518  ? 19  ARG A CA   1 
ATOM   268  C C    . ARG A 1 18  ? 95.93193  -34.81650 11.77043 1.000 57.67923  ? 19  ARG A C    1 
ATOM   269  O O    . ARG A 1 18  ? 96.19194  -34.36488 12.88621 1.000 54.45706  ? 19  ARG A O    1 
ATOM   270  C CB   . ARG A 1 18  ? 95.23769  -33.42598 9.83597  1.000 57.93620  ? 19  ARG A CB   1 
ATOM   271  C CG   . ARG A 1 18  ? 95.61491  -32.40975 8.79605  1.000 66.36935  ? 19  ARG A CG   1 
ATOM   272  C CD   . ARG A 1 18  ? 94.45150  -31.46307 8.62055  1.000 63.80673  ? 19  ARG A CD   1 
ATOM   273  N NE   . ARG A 1 18  ? 93.45328  -31.99921 7.72269  1.000 62.54242  ? 19  ARG A NE   1 
ATOM   274  C CZ   . ARG A 1 18  ? 92.14185  -31.85633 7.86283  1.000 63.95983  ? 19  ARG A CZ   1 
ATOM   275  N NH1  . ARG A 1 18  ? 91.61359  -31.35258 8.95393  1.000 55.47187  ? 19  ARG A NH1  1 
ATOM   276  N NH2  . ARG A 1 18  ? 91.33678  -32.22652 6.86848  1.000 66.07412  ? 19  ARG A NH2  1 
ATOM   277  H H    . ARG A 1 18  ? 96.62520  -35.12559 8.78928  1.000 66.38134  ? 19  ARG A H    1 
ATOM   278  H HA   . ARG A 1 18  ? 97.10659  -33.49432 10.72158 1.000 71.74148  ? 19  ARG A HA   1 
ATOM   279  H HB2  . ARG A 1 18  ? 94.67792  -34.09056 9.40483  1.000 69.59471  ? 19  ARG A HB2  1 
ATOM   280  H HB3  . ARG A 1 18  ? 94.73440  -32.96499 10.52524 1.000 69.59471  ? 19  ARG A HB3  1 
ATOM   281  H HG2  . ARG A 1 18  ? 96.39314  -31.90840 9.08572  1.000 79.71448  ? 19  ARG A HG2  1 
ATOM   282  H HG3  . ARG A 1 18  ? 95.79892  -32.84901 7.95101  1.000 79.71448  ? 19  ARG A HG3  1 
ATOM   283  H HD2  . ARG A 1 18  ? 94.03313  -31.30729 9.48171  1.000 76.63935  ? 19  ARG A HD2  1 
ATOM   284  H HD3  . ARG A 1 18  ? 94.77334  -30.62563 8.25173  1.000 76.63935  ? 19  ARG A HD3  1 
ATOM   285  H HE   . ARG A 1 18  ? 93.73200  -32.44668 7.04321  1.000 75.12217  ? 19  ARG A HE   1 
ATOM   286  H HH11 . ARG A 1 18  ? 92.12102  -31.10476 9.60254  1.000 66.63751  ? 19  ARG A HH11 1 
ATOM   287  H HH12 . ARG A 1 18  ? 90.76009  -31.27038 9.02011  1.000 66.63751  ? 19  ARG A HH12 1 
ATOM   288  H HH21 . ARG A 1 18  ? 91.66858  -32.55394 6.14577  1.000 79.36021  ? 19  ARG A HH21 1 
ATOM   289  H HH22 . ARG A 1 18  ? 90.48514  -32.13812 6.94912  1.000 79.36021  ? 19  ARG A HH22 1 
ATOM   290  N N    . LEU A 1 19  ? 95.13630  -35.84868 11.61591 1.000 55.82382  ? 20  LEU A N    1 
ATOM   291  C CA   . LEU A 1 19  ? 94.61958  -36.54758 12.77369 1.000 53.73053  ? 20  LEU A CA   1 
ATOM   292  C C    . LEU A 1 19  ? 95.74347  -37.11830 13.63247 1.000 54.23547  ? 20  LEU A C    1 
ATOM   293  O O    . LEU A 1 19  ? 95.69093  -37.04506 14.86924 1.000 52.24740  ? 20  LEU A O    1 
ATOM   294  C CB   . LEU A 1 19  ? 93.66319  -37.62459 12.30721 1.000 48.05649  ? 20  LEU A CB   1 
ATOM   295  C CG   . LEU A 1 19  ? 93.09118  -38.43273 13.45687 1.000 59.87342  ? 20  LEU A CG   1 
ATOM   296  C CD1  . LEU A 1 19  ? 92.12780  -37.63661 14.30701 1.000 52.54674  ? 20  LEU A CD1  1 
ATOM   297  C CD2  . LEU A 1 19  ? 92.49039  -39.63013 12.73920 1.000 49.34844  ? 20  LEU A CD2  1 
ATOM   298  H H    . LEU A 1 19  ? 94.87954  -36.16571 10.85883 1.000 67.05985  ? 20  LEU A H    1 
ATOM   299  H HA   . LEU A 1 19  ? 94.12798  -35.93138 13.33896 1.000 64.54790  ? 20  LEU A HA   1 
ATOM   300  H HB2  . LEU A 1 19  ? 92.92553  -37.20863 11.83421 1.000 57.73905  ? 20  LEU A HB2  1 
ATOM   301  H HB3  . LEU A 1 19  ? 94.13547  -38.23218 11.71672 1.000 57.73905  ? 20  LEU A HB3  1 
ATOM   302  H HG   . LEU A 1 19  ? 93.73735  -38.70723 14.12621 1.000 71.91938  ? 20  LEU A HG   1 
ATOM   303  H HD11 . LEU A 1 19  ? 91.79641  -38.20184 15.02227 1.000 63.12735  ? 20  LEU A HD11 1 
ATOM   304  H HD12 . LEU A 1 19  ? 92.59315  -36.87110 14.67896 1.000 63.12735  ? 20  LEU A HD12 1 
ATOM   305  H HD13 . LEU A 1 19  ? 91.38999  -37.33788 13.75266 1.000 63.12735  ? 20  LEU A HD13 1 
ATOM   306  H HD21 . LEU A 1 19  ? 92.07089  -40.21188 13.39226 1.000 59.28940  ? 20  LEU A HD21 1 
ATOM   307  H HD22 . LEU A 1 19  ? 91.82938  -39.31734 12.10192 1.000 59.28940  ? 20  LEU A HD22 1 
ATOM   308  H HD23 . LEU A 1 19  ? 93.19638  -40.10760 12.27606 1.000 59.28940  ? 20  LEU A HD23 1 
ATOM   309  N N    . GLY A 1 20  ? 96.80408  -37.60550 13.01156 1.000 49.57522  ? 21  GLY A N    1 
ATOM   310  C CA   . GLY A 1 20  ? 97.88815  -38.16564 13.79704 1.000 52.57374  ? 21  GLY A CA   1 
ATOM   311  C C    . GLY A 1 20  ? 98.67746  -37.11979 14.55929 1.000 54.63947  ? 21  GLY A C    1 
ATOM   312  O O    . GLY A 1 20  ? 99.06994  -37.34882 15.71603 1.000 48.37807  ? 21  GLY A O    1 
ATOM   313  H H    . GLY A 1 20  ? 96.91901  -37.62393 12.15947 1.000 59.56153  ? 21  GLY A H    1 
ATOM   314  H HA2  . GLY A 1 20  ? 97.52326  -38.79537 14.43829 1.000 63.15976  ? 21  GLY A HA2  1 
ATOM   315  H HA3  . GLY A 1 20  ? 98.49889  -38.63414 13.20678 1.000 63.15976  ? 21  GLY A HA3  1 
ATOM   316  N N    . ARG A 1 21  ? 98.94676  -35.97487 13.92056 1.000 52.08554  ? 22  ARG A N    1 
ATOM   317  C CA   . ARG A 1 21  ? 99.59901  -34.87316 14.62287 1.000 61.15244  ? 22  ARG A CA   1 
ATOM   318  C C    . ARG A 1 21  ? 98.70905  -34.37800 15.75419 1.000 55.38815  ? 22  ARG A C    1 
ATOM   319  O O    . ARG A 1 21  ? 99.16306  -34.09551 16.86171 1.000 49.42435  ? 22  ARG A O    1 
ATOM   320  C CB   . ARG A 1 21  ? 99.89739  -33.71868 13.65940 1.000 65.98207  ? 22  ARG A CB   1 
ATOM   321  C CG   . ARG A 1 21  ? 101.14697 -33.90132 12.76860 1.000 80.54282  ? 22  ARG A CG   1 
ATOM   322  C CD   . ARG A 1 21  ? 101.61172 -32.57718 12.09865 1.000 79.95049  ? 22  ARG A CD   1 
ATOM   323  N NE   . ARG A 1 21  ? 100.67253 -32.13102 11.07295 1.000 101.68335 ? 22  ARG A NE   1 
ATOM   324  C CZ   . ARG A 1 21  ? 99.74817  -31.18678 11.23435 1.000 106.28188 ? 22  ARG A CZ   1 
ATOM   325  N NH1  . ARG A 1 21  ? 99.64834  -30.49974 12.36203 1.000 128.76948 ? 22  ARG A NH1  1 
ATOM   326  N NH2  . ARG A 1 21  ? 98.90593  -30.91983 10.23121 1.000 92.14997  ? 22  ARG A NH2  1 
ATOM   327  H H    . ARG A 1 21  ? 98.76419  -35.81611 13.09530 1.000 62.57392  ? 22  ARG A H    1 
ATOM   328  H HA   . ARG A 1 21  ? 100.44353 -35.18595 14.98323 1.000 73.45419  ? 22  ARG A HA   1 
ATOM   329  H HB2  . ARG A 1 21  ? 99.13552  -33.60948 13.06904 1.000 79.24975  ? 22  ARG A HB2  1 
ATOM   330  H HB3  . ARG A 1 21  ? 100.03063 -32.91224 14.18171 1.000 79.24975  ? 22  ARG A HB3  1 
ATOM   331  H HG2  . ARG A 1 21  ? 101.87765 -34.23304 13.31355 1.000 96.72265  ? 22  ARG A HG2  1 
ATOM   332  H HG3  . ARG A 1 21  ? 100.94299 -34.53683 12.06474 1.000 96.72265  ? 22  ARG A HG3  1 
ATOM   333  H HD2  . ARG A 1 21  ? 101.67769 -31.88312 12.77307 1.000 96.01185  ? 22  ARG A HD2  1 
ATOM   334  H HD3  . ARG A 1 21  ? 102.47564 -32.71620 11.68005 1.000 96.01185  ? 22  ARG A HD3  1 
ATOM   335  H HE   . ARG A 1 21  ? 100.72060 -32.50909 10.30201 1.000 122.09129 ? 22  ARG A HE   1 
ATOM   336  H HH11 . ARG A 1 21  ? 100.18844 -30.65926 13.01199 1.000 154.59464 ? 22  ARG A HH11 1 
ATOM   337  H HH12 . ARG A 1 21  ? 99.04341  -29.89404 12.44442 1.000 154.59464 ? 22  ARG A HH12 1 
ATOM   338  H HH21 . ARG A 1 21  ? 98.96509  -31.35608 9.49244  1.000 110.65123 ? 22  ARG A HH21 1 
ATOM   339  H HH22 . ARG A 1 21  ? 98.30491  -30.31184 10.32462 1.000 110.65123 ? 22  ARG A HH22 1 
ATOM   340  N N    . SER A 1 22  ? 97.42615  -34.29100 15.48827 1.000 50.41105  ? 23  SER A N    1 
ATOM   341  C CA   . SER A 1 22  ? 96.48236  -33.77924 16.46328 1.000 51.21189  ? 23  SER A CA   1 
ATOM   342  C C    . SER A 1 22  ? 96.42397  -34.67264 17.71043 1.000 56.72697  ? 23  SER A C    1 
ATOM   343  O O    . SER A 1 22  ? 96.45341  -34.18383 18.85242 1.000 49.93778  ? 23  SER A O    1 
ATOM   344  C CB   . SER A 1 22  ? 95.15796  -33.66521 15.70509 1.000 53.45862  ? 23  SER A CB   1 
ATOM   345  O OG   . SER A 1 22  ? 94.13839  -33.06826 16.44756 1.000 74.80388  ? 23  SER A OG   1 
ATOM   346  H H    . SER A 1 22  ? 97.06624  -34.52329 14.74255 1.000 60.56453  ? 23  SER A H    1 
ATOM   347  H HA   . SER A 1 22  ? 96.72346  -32.90875 16.81687 1.000 61.52554  ? 23  SER A HA   1 
ATOM   348  H HB2  . SER A 1 22  ? 95.30766  -33.13146 14.90910 1.000 64.22161  ? 23  SER A HB2  1 
ATOM   349  H HB3  . SER A 1 22  ? 94.87128  -34.55800 15.45681 1.000 64.22161  ? 23  SER A HB3  1 
ATOM   350  H HG   . SER A 1 22  ? 93.42413  -33.06676 16.00547 1.000 89.83592  ? 23  SER A HG   1 
ATOM   351  N N    . LEU A 1 23  ? 96.40199  -35.98664 17.51421 1.000 56.33221  ? 24  LEU A N    1 
ATOM   352  C CA   . LEU A 1 23  ? 96.38484  -36.89410 18.65069 1.000 54.28377  ? 24  LEU A CA   1 
ATOM   353  C C    . LEU A 1 23  ? 97.70944  -36.85427 19.38795 1.000 49.76267  ? 24  LEU A C    1 
ATOM   354  O O    . LEU A 1 23  ? 97.74300  -37.01954 20.61503 1.000 51.45487  ? 24  LEU A O    1 
ATOM   355  C CB   . LEU A 1 23  ? 96.09517  -38.31593 18.16896 1.000 48.17525  ? 24  LEU A CB   1 
ATOM   356  C CG   . LEU A 1 23  ? 94.68360  -38.49177 17.63207 1.000 51.85412  ? 24  LEU A CG   1 
ATOM   357  C CD1  . LEU A 1 23  ? 94.57602  -39.70420 16.72906 1.000 50.14432  ? 24  LEU A CD1  1 
ATOM   358  C CD2  . LEU A 1 23  ? 93.74822  -38.57299 18.80661 1.000 51.70905  ? 24  LEU A CD2  1 
ATOM   359  H H    . LEU A 1 23  ? 96.39665  -36.37142 16.74510 1.000 67.66991  ? 24  LEU A H    1 
ATOM   360  H HA   . LEU A 1 23  ? 95.68116  -36.62735 19.26272 1.000 65.21179  ? 24  LEU A HA   1 
ATOM   361  H HB2  . LEU A 1 23  ? 96.71557  -38.53785 17.45709 1.000 57.88156  ? 24  LEU A HB2  1 
ATOM   362  H HB3  . LEU A 1 23  ? 96.21063  -38.92809 18.91248 1.000 57.88156  ? 24  LEU A HB3  1 
ATOM   363  H HG   . LEU A 1 23  ? 94.43288  -37.73684 17.07699 1.000 62.29622  ? 24  LEU A HG   1 
ATOM   364  H HD11 . LEU A 1 23  ? 93.65795  -39.79410 16.42912 1.000 60.24445  ? 24  LEU A HD11 1 
ATOM   365  H HD12 . LEU A 1 23  ? 95.16284  -39.58293 15.96629 1.000 60.24445  ? 24  LEU A HD12 1 
ATOM   366  H HD13 . LEU A 1 23  ? 94.84001  -40.49348 17.22731 1.000 60.24445  ? 24  LEU A HD13 1 
ATOM   367  H HD21 . LEU A 1 23  ? 92.84638  -38.72279 18.48235 1.000 62.12213  ? 24  LEU A HD21 1 
ATOM   368  H HD22 . LEU A 1 23  ? 94.02097  -39.30842 19.37727 1.000 62.12213  ? 24  LEU A HD22 1 
ATOM   369  H HD23 . LEU A 1 23  ? 93.78796  -37.73893 19.30024 1.000 62.12213  ? 24  LEU A HD23 1 
ATOM   370  N N    . THR A 1 24  ? 98.81552  -36.67887 18.64905 1.000 48.39772  ? 25  THR A N    1 
ATOM   371  C CA   . THR A 1 24  ? 100.12339 -36.64046 19.29150 1.000 50.58267  ? 25  THR A CA   1 
ATOM   372  C C    . THR A 1 24  ? 100.22072 -35.41929 20.19394 1.000 55.38840  ? 25  THR A C    1 
ATOM   373  O O    . THR A 1 24  ? 100.66770 -35.51563 21.34416 1.000 50.95902  ? 25  THR A O    1 
ATOM   374  C CB   . THR A 1 24  ? 101.24093 -36.62663 18.24853 1.000 55.83707  ? 25  THR A CB   1 
ATOM   375  O OG1  . THR A 1 24  ? 101.17091 -37.81603 17.45421 1.000 58.21851  ? 25  THR A OG1  1 
ATOM   376  C CG2  . THR A 1 24  ? 102.59422 -36.57250 18.95986 1.000 56.38322  ? 25  THR A CG2  1 
ATOM   377  H H    . THR A 1 24  ? 98.82942  -36.58247 17.79459 1.000 58.14853  ? 25  THR A H    1 
ATOM   378  H HA   . THR A 1 24  ? 100.24075 -37.44249 19.82429 1.000 60.77048  ? 25  THR A HA   1 
ATOM   379  H HB   . THR A 1 24  ? 101.15179 -35.85329 17.66983 1.000 67.07575  ? 25  THR A HB   1 
ATOM   380  H HG1  . THR A 1 24  ? 100.43066 -37.85442 17.05903 1.000 69.93348  ? 25  THR A HG1  1 
ATOM   381  H HG21 . THR A 1 24  ? 103.30849 -36.74968 18.32795 1.000 67.73113  ? 25  THR A HG21 1 
ATOM   382  H HG22 . THR A 1 24  ? 102.72928 -35.69456 19.34958 1.000 67.73113  ? 25  THR A HG22 1 
ATOM   383  H HG23 . THR A 1 24  ? 102.62532 -37.23803 19.66484 1.000 67.73113  ? 25  THR A HG23 1 
ATOM   384  N N    . ALA A 1 25  ? 99.74053  -34.26670 19.70868 1.000 56.84785  ? 26  ALA A N    1 
ATOM   385  C CA   . ALA A 1 25  ? 99.76561  -33.06844 20.54502 1.000 58.77279  ? 26  ALA A CA   1 
ATOM   386  C C    . ALA A 1 25  ? 98.82795  -33.20165 21.73772 1.000 47.21643  ? 26  ALA A C    1 
ATOM   387  O O    . ALA A 1 25  ? 99.12477  -32.67720 22.80999 1.000 51.57908  ? 26  ALA A O    1 
ATOM   388  C CB   . ALA A 1 25  ? 99.39783  -31.81649 19.73715 1.000 55.28471  ? 26  ALA A CB   1 
ATOM   389  H H    . ALA A 1 25  ? 99.40629  -34.15841 18.92373 1.000 68.28869  ? 26  ALA A H    1 
ATOM   390  H HA   . ALA A 1 25  ? 100.67357 -32.95837 20.86813 1.000 70.59862  ? 26  ALA A HA   1 
ATOM   391  H HB1  . ALA A 1 25  ? 99.46803  -31.03805 20.31162 1.000 66.41292  ? 26  ALA A HB1  1 
ATOM   392  H HB2  . ALA A 1 25  ? 100.00993 -31.73206 18.98942 1.000 66.41292  ? 26  ALA A HB2  1 
ATOM   393  H HB3  . ALA A 1 25  ? 98.48850  -31.90650 19.41171 1.000 66.41292  ? 26  ALA A HB3  1 
ATOM   394  N N    . ALA A 1 26  ? 97.67712  -33.86889 21.57119 1.000 48.94362  ? 27  ALA A N    1 
ATOM   395  C CA   . ALA A 1 26  ? 96.75773  -34.00571 22.70249 1.000 49.25040  ? 27  ALA A CA   1 
ATOM   396  C C    . ALA A 1 26  ? 97.44470  -34.71541 23.86554 1.000 52.96549  ? 27  ALA A C    1 
ATOM   397  O O    . ALA A 1 26  ? 97.29706  -34.33046 25.03435 1.000 49.04141  ? 27  ALA A O    1 
ATOM   398  C CB   . ALA A 1 26  ? 95.48346  -34.75329 22.28516 1.000 45.30863  ? 27  ALA A CB   1 
ATOM   399  H H    . ALA A 1 26  ? 97.41650  -34.23756 20.83924 1.000 58.80361  ? 27  ALA A H    1 
ATOM   400  H HA   . ALA A 1 26  ? 96.48622  -33.12125 22.99387 1.000 59.17175  ? 27  ALA A HA   1 
ATOM   401  H HB1  . ALA A 1 26  ? 94.90958  -34.85637 23.06036 1.000 54.44162  ? 27  ALA A HB1  1 
ATOM   402  H HB2  . ALA A 1 26  ? 95.02602  -34.24007 21.60086 1.000 54.44162  ? 27  ALA A HB2  1 
ATOM   403  H HB3  . ALA A 1 26  ? 95.72839  -35.62477 21.93670 1.000 54.44162  ? 27  ALA A HB3  1 
ATOM   404  N N    . VAL A 1 27  ? 98.22014  -35.74700 23.55702 1.000 54.61447  ? 28  VAL A N    1 
ATOM   405  C CA   . VAL A 1 27  ? 98.92462  -36.47459 24.60043 1.000 50.75439  ? 28  VAL A CA   1 
ATOM   406  C C    . VAL A 1 27  ? 99.84669  -35.54189 25.35058 1.000 54.54790  ? 28  VAL A C    1 
ATOM   407  O O    . VAL A 1 27  ? 99.93167  -35.61459 26.58094 1.000 48.93782  ? 28  VAL A O    1 
ATOM   408  C CB   . VAL A 1 27  ? 99.67868  -37.67135 23.98863 1.000 56.06314  ? 28  VAL A CB   1 
ATOM   409  C CG1  . VAL A 1 27  ? 100.67894 -38.26327 24.93893 1.000 54.60550  ? 28  VAL A CG1  1 
ATOM   410  C CG2  . VAL A 1 27  ? 98.68005  -38.73691 23.55146 1.000 54.63096  ? 28  VAL A CG2  1 
ATOM   411  H H    . VAL A 1 27  ? 98.35364  -36.04232 22.76043 1.000 65.60863  ? 28  VAL A H    1 
ATOM   412  H HA   . VAL A 1 27  ? 98.28115  -36.82535 25.23589 1.000 60.97654  ? 28  VAL A HA   1 
ATOM   413  H HB   . VAL A 1 27  ? 100.17508 -37.35025 23.21961 1.000 67.34704  ? 28  VAL A HB   1 
ATOM   414  H HG11 . VAL A 1 27  ? 100.97828 -39.11765 24.59059 1.000 65.59786  ? 28  VAL A HG11 1 
ATOM   415  H HG12 . VAL A 1 27  ? 101.43216 -37.65777 25.02218 1.000 65.59786  ? 28  VAL A HG12 1 
ATOM   416  H HG13 . VAL A 1 27  ? 100.25759 -38.38793 25.80370 1.000 65.59786  ? 28  VAL A HG13 1 
ATOM   417  H HG21 . VAL A 1 27  ? 99.16532  -39.52960 23.27388 1.000 65.62842  ? 28  VAL A HG21 1 
ATOM   418  H HG22 . VAL A 1 27  ? 98.09824  -38.94967 24.29787 1.000 65.62842  ? 28  VAL A HG22 1 
ATOM   419  H HG23 . VAL A 1 27  ? 98.15594  -38.39368 22.81091 1.000 65.62842  ? 28  VAL A HG23 1 
ATOM   420  N N    . GLN A 1 28  ? 100.50386 -34.61811 24.63740 1.000 50.00483  ? 29  GLN A N    1 
ATOM   421  C CA   . GLN A 1 28  ? 101.51668 -33.74955 25.23375 1.000 58.40996  ? 29  GLN A CA   1 
ATOM   422  C C    . GLN A 1 28  ? 100.94963 -32.65961 26.13578 1.000 52.02224  ? 29  GLN A C    1 
ATOM   423  O O    . GLN A 1 28  ? 101.73813 -31.97495 26.79134 1.000 53.91632  ? 29  GLN A O    1 
ATOM   424  C CB   . GLN A 1 28  ? 102.33818 -33.07847 24.11892 1.000 59.28435  ? 29  GLN A CB   1 
ATOM   425  C CG   . GLN A 1 28  ? 103.39073 -33.97677 23.49802 1.000 68.32316  ? 29  GLN A CG   1 
ATOM   426  C CD   . GLN A 1 28  ? 104.00342 -33.37991 22.24144 1.000 71.42104  ? 29  GLN A CD   1 
ATOM   427  O OE1  . GLN A 1 28  ? 105.07870 -32.75848 22.28075 1.000 75.57333  ? 29  GLN A OE1  1 
ATOM   428  N NE2  . GLN A 1 28  ? 103.31471 -33.55348 21.11105 1.000 64.60165  ? 29  GLN A NE2  1 
ATOM   429  H H    . GLN A 1 28  ? 100.37788 -34.47582 23.79866 1.000 60.07706  ? 29  GLN A H    1 
ATOM   430  H HA   . GLN A 1 28  ? 102.09576 -34.30654 25.77719 1.000 70.16322  ? 29  GLN A HA   1 
ATOM   431  H HB2  . GLN A 1 28  ? 101.73414 -32.80071 23.41260 1.000 71.21249  ? 29  GLN A HB2  1 
ATOM   432  H HB3  . GLN A 1 28  ? 102.79215 -32.30581 24.49015 1.000 71.21249  ? 29  GLN A HB3  1 
ATOM   433  H HG2  . GLN A 1 28  ? 104.10317 -34.12024 24.14047 1.000 82.05906  ? 29  GLN A HG2  1 
ATOM   434  H HG3  . GLN A 1 28  ? 102.98304 -34.82413 23.25998 1.000 82.05906  ? 29  GLN A HG3  1 
ATOM   435  H HE21 . GLN A 1 28  ? 102.56964 -33.98280 21.12309 1.000 77.59325  ? 29  GLN A HE21 1 
ATOM   436  H HE22 . GLN A 1 28  ? 103.61613 -33.23598 20.37082 1.000 77.59325  ? 29  GLN A HE22 1 
ATOM   437  N N    . THR A 1 29  ? 99.62836  -32.47831 26.19271 1.000 48.42708  ? 30  THR A N    1 
ATOM   438  C CA   . THR A 1 29  ? 99.06394  -31.54206 27.16004 1.000 54.11590  ? 30  THR A CA   1 
ATOM   439  C C    . THR A 1 29  ? 98.99487  -32.11314 28.57564 1.000 58.67354  ? 30  THR A C    1 
ATOM   440  O O    . THR A 1 29  ? 98.70010  -31.38003 29.54295 1.000 56.12408  ? 30  THR A O    1 
ATOM   441  C CB   . THR A 1 29  ? 97.65268  -31.13151 26.75159 1.000 54.98624  ? 30  THR A CB   1 
ATOM   442  O OG1  . THR A 1 29  ? 96.74433  -32.24046 26.88223 1.000 48.86807  ? 30  THR A OG1  1 
ATOM   443  C CG2  . THR A 1 29  ? 97.64927  -30.64831 25.32062 1.000 48.62732  ? 30  THR A CG2  1 
ATOM   444  H H    . THR A 1 29  ? 99.05327  -32.87714 25.69291 1.000 58.18377  ? 30  THR A H    1 
ATOM   445  H HA   . THR A 1 29  ? 99.62784  -30.75283 27.16505 1.000 65.01035  ? 30  THR A HA   1 
ATOM   446  H HB   . THR A 1 29  ? 97.35001  -30.41408 27.33002 1.000 66.05475  ? 30  THR A HB   1 
ATOM   447  H HG1  . THR A 1 29  ? 96.93321  -32.83443 26.31909 1.000 58.71295  ? 30  THR A HG1  1 
ATOM   448  H HG21 . THR A 1 29  ? 96.77277  -30.30329 25.08905 1.000 58.42405  ? 30  THR A HG21 1 
ATOM   449  H HG22 . THR A 1 29  ? 98.30531  -29.94290 25.20708 1.000 58.42405  ? 30  THR A HG22 1 
ATOM   450  H HG23 . THR A 1 29  ? 97.86746  -31.38033 24.72275 1.000 58.42405  ? 30  THR A HG23 1 
ATOM   451  N N    . VAL A 1 30  ? 99.20931  -33.41529 28.71186 1.000 52.07001  ? 31  VAL A N    1 
ATOM   452  C CA   . VAL A 1 30  ? 99.19543  -34.07389 29.99736 1.000 56.59805  ? 31  VAL A CA   1 
ATOM   453  C C    . VAL A 1 30  ? 100.51023 -34.78246 30.26850 1.000 58.40236  ? 31  VAL A C    1 
ATOM   454  O O    . VAL A 1 30  ? 101.08033 -34.64582 31.34607 1.000 59.03534  ? 31  VAL A O    1 
ATOM   455  C CB   . VAL A 1 30  ? 98.02029  -35.05264 30.08760 1.000 51.95918  ? 31  VAL A CB   1 
ATOM   456  C CG1  . VAL A 1 30  ? 98.02160  -35.69102 31.44603 1.000 56.09205  ? 31  VAL A CG1  1 
ATOM   457  C CG2  . VAL A 1 30  ? 96.69045  -34.34758 29.86262 1.000 52.53310  ? 31  VAL A CG2  1 
ATOM   458  H H    . VAL A 1 30  ? 99.36845  -33.94621 28.05429 1.000 62.55527  ? 31  VAL A H    1 
ATOM   459  H HA   . VAL A 1 30  ? 99.08009  -33.41029 30.69538 1.000 67.98893  ? 31  VAL A HA   1 
ATOM   460  H HB   . VAL A 1 30  ? 98.11986  -35.72659 29.39710 1.000 62.42228  ? 31  VAL A HB   1 
ATOM   461  H HG11 . VAL A 1 30  ? 97.13856  -36.04905 31.62756 1.000 67.38173  ? 31  VAL A HG11 1 
ATOM   462  H HG12 . VAL A 1 30  ? 98.67729  -36.40574 31.45846 1.000 67.38173  ? 31  VAL A HG12 1 
ATOM   463  H HG13 . VAL A 1 30  ? 98.24978  -35.02122 32.10951 1.000 67.38173  ? 31  VAL A HG13 1 
ATOM   464  H HG21 . VAL A 1 30  ? 95.96887  -34.97540 30.02406 1.000 63.11099  ? 31  VAL A HG21 1 
ATOM   465  H HG22 . VAL A 1 30  ? 96.62172  -33.59968 30.47647 1.000 63.11099  ? 31  VAL A HG22 1 
ATOM   466  H HG23 . VAL A 1 30  ? 96.65292  -34.02876 28.94728 1.000 63.11099  ? 31  VAL A HG23 1 
ATOM   467  N N    . VAL A 1 31  ? 101.04887 -35.47267 29.28058 1.000 56.01196  ? 32  VAL A N    1 
ATOM   468  C CA   . VAL A 1 31  ? 102.25447 -36.27233 29.44418 1.000 58.69399  ? 32  VAL A CA   1 
ATOM   469  C C    . VAL A 1 31  ? 103.40676 -35.52040 28.82230 1.000 62.73768  ? 32  VAL A C    1 
ATOM   470  O O    . VAL A 1 31  ? 103.42722 -35.34131 27.59166 1.000 61.66298  ? 32  VAL A O    1 
ATOM   471  C CB   . VAL A 1 31  ? 102.09180 -37.65648 28.80889 1.000 58.50263  ? 32  VAL A CB   1 
ATOM   472  C CG1  . VAL A 1 31  ? 103.35629 -38.43502 28.94704 1.000 60.60260  ? 32  VAL A CG1  1 
ATOM   473  C CG2  . VAL A 1 31  ? 100.91594 -38.34340 29.45157 1.000 56.42854  ? 32  VAL A CG2  1 
ATOM   474  H H    . VAL A 1 31  ? 100.72744 -35.49597 28.48325 1.000 67.28562  ? 32  VAL A H    1 
ATOM   475  H HA   . VAL A 1 31  ? 102.44246 -36.38555 30.38903 1.000 70.50405  ? 32  VAL A HA   1 
ATOM   476  H HB   . VAL A 1 31  ? 101.91522 -37.58711 27.85762 1.000 70.27442  ? 32  VAL A HB   1 
ATOM   477  H HG11 . VAL A 1 31  ? 103.19046 -39.35516 28.68867 1.000 72.79439  ? 32  VAL A HG11 1 
ATOM   478  H HG12 . VAL A 1 31  ? 104.03148 -38.04583 28.36949 1.000 72.79439  ? 32  VAL A HG12 1 
ATOM   479  H HG13 . VAL A 1 31  ? 103.65023 -38.39866 29.87072 1.000 72.79439  ? 32  VAL A HG13 1 
ATOM   480  H HG21 . VAL A 1 31  ? 100.87994 -39.26242 29.14336 1.000 67.78552  ? 32  VAL A HG21 1 
ATOM   481  H HG22 . VAL A 1 31  ? 101.02549 -38.32171 30.41512 1.000 67.78552  ? 32  VAL A HG22 1 
ATOM   482  H HG23 . VAL A 1 31  ? 100.10260 -37.87824 29.20058 1.000 67.78552  ? 32  VAL A HG23 1 
ATOM   483  N N    . PRO A 1 32  ? 104.37474 -35.11887 29.56741 1.000 68.24257  ? 33  PRO A N    1 
ATOM   484  C CA   . PRO A 1 32  ? 105.49215 -34.34104 29.04650 1.000 71.52023  ? 33  PRO A CA   1 
ATOM   485  C C    . PRO A 1 32  ? 106.52823 -35.19536 28.32874 1.000 74.25916  ? 33  PRO A C    1 
ATOM   486  O O    . PRO A 1 32  ? 107.72474 -35.13929 28.62372 1.000 73.53891  ? 33  PRO A O    1 
ATOM   487  C CB   . PRO A 1 32  ? 106.08261 -33.70062 30.31227 1.000 68.93561  ? 33  PRO A CB   1 
ATOM   488  C CG   . PRO A 1 32  ? 105.84136 -34.74768 31.34473 1.000 72.76038  ? 33  PRO A CG   1 
ATOM   489  C CD   . PRO A 1 32  ? 104.50364 -35.37818 31.02004 1.000 69.02229  ? 33  PRO A CD   1 
ATOM   490  H HA   . PRO A 1 32  ? 105.16782 -33.64469 28.45421 1.000 85.89555  ? 33  PRO A HA   1 
ATOM   491  H HB2  . PRO A 1 32  ? 107.02974 -33.52672 30.19565 1.000 82.79400  ? 33  PRO A HB2  1 
ATOM   492  H HB3  . PRO A 1 32  ? 105.61772 -32.87636 30.52528 1.000 82.79400  ? 33  PRO A HB3  1 
ATOM   493  H HG2  . PRO A 1 32  ? 106.54863 -35.41033 31.30526 1.000 87.38373  ? 33  PRO A HG2  1 
ATOM   494  H HG3  . PRO A 1 32  ? 105.82000 -34.33717 32.22333 1.000 87.38373  ? 33  PRO A HG3  1 
ATOM   495  H HD2  . PRO A 1 32  ? 104.51288 -36.33037 31.20483 1.000 82.89802  ? 33  PRO A HD2  1 
ATOM   496  H HD3  . PRO A 1 32  ? 103.78737 -34.95103 31.51543 1.000 82.89802  ? 33  PRO A HD3  1 
ATOM   497  N N    . ALA A 1 33  ? 106.05473 -36.01833 27.38306 1.000 72.59466  ? 34  ALA A N    1 
ATOM   498  C CA   . ALA A 1 33  ? 106.96318 -36.74134 26.50263 1.000 78.26466  ? 34  ALA A CA   1 
ATOM   499  C C    . ALA A 1 33  ? 107.27451 -35.91171 25.26975 1.000 79.05052  ? 34  ALA A C    1 
ATOM   500  O O    . ALA A 1 33  ? 106.50191 -35.02410 24.87794 1.000 74.07797  ? 34  ALA A O    1 
ATOM   501  C CB   . ALA A 1 33  ? 106.36162 -38.08526 26.09727 1.000 75.00942  ? 34  ALA A CB   1 
ATOM   502  H H    . ALA A 1 33  ? 105.22038 -36.16853 27.23847 1.000 87.18486  ? 34  ALA A H    1 
ATOM   503  H HA   . ALA A 1 33  ? 107.79379 -36.92134 26.97018 1.000 93.98886  ? 34  ALA A HA   1 
ATOM   504  H HB1  . ALA A 1 33  ? 107.00392 -38.56762 25.55351 1.000 90.08257  ? 34  ALA A HB1  1 
ATOM   505  H HB2  . ALA A 1 33  ? 106.15739 -38.59407 26.89746 1.000 90.08257  ? 34  ALA A HB2  1 
ATOM   506  H HB3  . ALA A 1 33  ? 105.55036 -37.92780 25.58937 1.000 90.08257  ? 34  ALA A HB3  1 
ATOM   507  N N    . PRO A 1 34  ? 108.43257 -36.15289 24.66065 1.000 82.39621  ? 35  PRO A N    1 
ATOM   508  C CA   . PRO A 1 34  ? 108.71127 -35.53598 23.35958 1.000 91.36703  ? 35  PRO A CA   1 
ATOM   509  C C    . PRO A 1 34  ? 107.89849 -36.21241 22.27291 1.000 91.80034  ? 35  PRO A C    1 
ATOM   510  O O    . PRO A 1 34  ? 107.61789 -37.42023 22.35290 1.000 87.92013  ? 35  PRO A O    1 
ATOM   511  C CB   . PRO A 1 34  ? 110.21485 -35.78958 23.16333 1.000 90.37539  ? 35  PRO A CB   1 
ATOM   512  C CG   . PRO A 1 34  ? 110.44202 -37.08532 23.91841 1.000 86.23939  ? 35  PRO A CG   1 
ATOM   513  C CD   . PRO A 1 34  ? 109.49695 -37.06823 25.10761 1.000 75.12615  ? 35  PRO A CD   1 
ATOM   514  H HA   . PRO A 1 34  ? 108.53226 -34.58275 23.37395 1.000 109.71171 ? 35  PRO A HA   1 
ATOM   515  H HB2  . PRO A 1 34  ? 110.42135 -35.88760 22.22065 1.000 108.52174 ? 35  PRO A HB2  1 
ATOM   516  H HB3  . PRO A 1 34  ? 110.73305 -35.06259 23.54263 1.000 108.52174 ? 35  PRO A HB3  1 
ATOM   517  H HG2  . PRO A 1 34  ? 110.24531 -37.83713 23.33791 1.000 103.55853 ? 35  PRO A HG2  1 
ATOM   518  H HG3  . PRO A 1 34  ? 111.36398 -37.12887 24.21675 1.000 103.55853 ? 35  PRO A HG3  1 
ATOM   519  H HD2  . PRO A 1 34  ? 109.14276 -37.95405 25.28299 1.000 90.22265  ? 35  PRO A HD2  1 
ATOM   520  H HD3  . PRO A 1 34  ? 109.94047 -36.72553 25.89928 1.000 90.22265  ? 35  PRO A HD3  1 
ATOM   521  N N    . PRO A 1 35  ? 107.51663 -35.48127 21.22475 1.000 97.35158  ? 36  PRO A N    1 
ATOM   522  C CA   . PRO A 1 35  ? 106.78397 -36.13653 20.12297 1.000 97.38998  ? 36  PRO A CA   1 
ATOM   523  C C    . PRO A 1 35  ? 107.44381 -37.43505 19.65493 1.000 94.32693  ? 36  PRO A C    1 
ATOM   524  O O    . PRO A 1 35  ? 106.73789 -38.40213 19.33912 1.000 85.99705  ? 36  PRO A O    1 
ATOM   525  C CB   . PRO A 1 35  ? 106.76267 -35.06772 19.01716 1.000 96.58568  ? 36  PRO A CB   1 
ATOM   526  C CG   . PRO A 1 35  ? 106.96496 -33.76558 19.73403 1.000 92.75160  ? 36  PRO A CG   1 
ATOM   527  C CD   . PRO A 1 35  ? 107.83908 -34.07119 20.92869 1.000 98.33231  ? 36  PRO A CD   1 
ATOM   528  H HA   . PRO A 1 35  ? 105.86987 -36.31727 20.39250 1.000 116.93925 ? 36  PRO A HA   1 
ATOM   529  H HB2  . PRO A 1 35  ? 107.48028 -35.23159 18.38542 1.000 115.97409 ? 36  PRO A HB2  1 
ATOM   530  H HB3  . PRO A 1 35  ? 105.90767 -35.08302 18.55931 1.000 115.97409 ? 36  PRO A HB3  1 
ATOM   531  H HG2  . PRO A 1 35  ? 107.40260 -33.13318 19.14288 1.000 111.37318 ? 36  PRO A HG2  1 
ATOM   532  H HG3  . PRO A 1 35  ? 106.10691 -33.41424 20.01902 1.000 111.37318 ? 36  PRO A HG3  1 
ATOM   533  H HD2  . PRO A 1 35  ? 108.77771 -33.97004 20.70590 1.000 118.07004 ? 36  PRO A HD2  1 
ATOM   534  H HD3  . PRO A 1 35  ? 107.61264 -33.49935 21.67877 1.000 118.07004 ? 36  PRO A HD3  1 
ATOM   535  N N    . GLU A 1 36  ? 108.78000 -37.48523 19.62509 1.000 100.74511 ? 37  GLU A N    1 
ATOM   536  C CA   . GLU A 1 36  ? 109.50603 -38.64889 19.13974 1.000 91.13001  ? 37  GLU A CA   1 
ATOM   537  C C    . GLU A 1 36  ? 109.17423 -39.92124 19.91196 1.000 89.30481  ? 37  GLU A C    1 
ATOM   538  O O    . GLU A 1 36  ? 109.40663 -41.02216 19.40795 1.000 92.98902  ? 37  GLU A O    1 
ATOM   539  C CB   . GLU A 1 36  ? 111.01810 -38.40694 19.23411 1.000 99.73487  ? 37  GLU A CB   1 
ATOM   540  C CG   . GLU A 1 36  ? 111.60042 -37.19437 18.49835 1.000 115.14581 ? 37  GLU A CG   1 
ATOM   541  C CD   . GLU A 1 36  ? 110.90133 -35.87485 18.81489 1.000 131.95601 ? 37  GLU A CD   1 
ATOM   542  O OE1  . GLU A 1 36  ? 110.23544 -35.77002 19.86002 1.000 121.04365 ? 37  GLU A OE1  1 
ATOM   543  O OE2  . GLU A 1 36  ? 110.95882 -34.95091 17.97378 1.000 116.59026 ? 37  GLU A OE2  1 
ATOM   544  H H    . GLU A 1 36  ? 109.29291 -36.84592 19.88550 1.000 120.96539 ? 37  GLU A H    1 
ATOM   545  H HA   . GLU A 1 36  ? 109.26004 -38.77980 18.21063 1.000 109.42728 ? 37  GLU A HA   1 
ATOM   546  H HB2  . GLU A 1 36  ? 111.24145 -38.29661 20.17158 1.000 119.75311 ? 37  GLU A HB2  1 
ATOM   547  H HB3  . GLU A 1 36  ? 111.46522 -39.18993 18.87646 1.000 119.75311 ? 37  GLU A HB3  1 
ATOM   548  H HG2  . GLU A 1 36  ? 112.53336 -37.09936 18.74635 1.000 138.24624 ? 37  GLU A HG2  1 
ATOM   549  H HG3  . GLU A 1 36  ? 111.52475 -37.34508 17.54312 1.000 138.24624 ? 37  GLU A HG3  1 
ATOM   550  N N    . ALA A 1 37  ? 108.68354 -39.80180 21.13300 1.000 87.34080  ? 38  ALA A N    1 
ATOM   551  C CA   . ALA A 1 37  ? 108.39425 -40.95562 21.96238 1.000 85.54582  ? 38  ALA A CA   1 
ATOM   552  C C    . ALA A 1 37  ? 106.95898 -41.43122 21.83471 1.000 77.04839  ? 38  ALA A C    1 
ATOM   553  O O    . ALA A 1 37  ? 106.58694 -42.40869 22.48988 1.000 76.52886  ? 38  ALA A O    1 
ATOM   554  C CB   . ALA A 1 37  ? 108.67924 -40.63421 23.43081 1.000 88.49990  ? 38  ALA A CB   1 
ATOM   555  H H    . ALA A 1 37  ? 108.50657 -39.04932 21.50990 1.000 104.88023 ? 38  ALA A H    1 
ATOM   556  H HA   . ALA A 1 37  ? 108.97929 -41.67940 21.68893 1.000 102.72626 ? 38  ALA A HA   1 
ATOM   557  H HB1  . ALA A 1 37  ? 108.48870 -41.41872 23.96854 1.000 106.27115 ? 38  ALA A HB1  1 
ATOM   558  H HB2  . ALA A 1 37  ? 109.61265 -40.38757 23.52471 1.000 106.27115 ? 38  ALA A HB2  1 
ATOM   559  H HB3  . ALA A 1 37  ? 108.11285 -39.89733 23.70849 1.000 106.27115 ? 38  ALA A HB3  1 
ATOM   560  N N    . ILE A 1 38  ? 106.13867 -40.74854 21.04948 1.000 72.13645  ? 39  ILE A N    1 
ATOM   561  C CA   . ILE A 1 38  ? 104.70224 -40.97745 21.01544 1.000 67.72001  ? 39  ILE A CA   1 
ATOM   562  C C    . ILE A 1 38  ? 104.34382 -41.60393 19.67283 1.000 65.18216  ? 39  ILE A C    1 
ATOM   563  O O    . ILE A 1 38  ? 104.69690 -41.08143 18.61082 1.000 56.67798  ? 39  ILE A O    1 
ATOM   564  C CB   . ILE A 1 38  ? 103.92281 -39.67127 21.24075 1.000 71.56395  ? 39  ILE A CB   1 
ATOM   565  C CG1  . ILE A 1 38  ? 104.23744 -39.06585 22.60721 1.000 67.16707  ? 39  ILE A CG1  1 
ATOM   566  C CG2  . ILE A 1 38  ? 102.41525 -39.89296 21.13808 1.000 63.29088  ? 39  ILE A CG2  1 
ATOM   567  C CD1  . ILE A 1 38  ? 103.62825 -37.68288 22.79976 1.000 62.22818  ? 39  ILE A CD1  1 
ATOM   568  H H    . ILE A 1 38  ? 106.39866 -40.12961 20.51195 1.000 86.63500  ? 39  ILE A H    1 
ATOM   569  H HA   . ILE A 1 38  ? 104.46064 -41.60392 21.71548 1.000 81.33527  ? 39  ILE A HA   1 
ATOM   570  H HB   . ILE A 1 38  ? 104.20628 -39.06023 20.54277 1.000 85.94801  ? 39  ILE A HB   1 
ATOM   571  H HG12 . ILE A 1 38  ? 103.88387 -39.64753 23.29825 1.000 80.67175  ? 39  ILE A HG12 1 
ATOM   572  H HG13 . ILE A 1 38  ? 105.19943 -38.98498 22.70179 1.000 80.67175  ? 39  ILE A HG13 1 
ATOM   573  H HG21 . ILE A 1 38  ? 101.95883 -39.06476 21.35407 1.000 76.02032  ? 39  ILE A HG21 1 
ATOM   574  H HG22 . ILE A 1 38  ? 102.19692 -40.16462 20.23286 1.000 76.02032  ? 39  ILE A HG22 1 
ATOM   575  H HG23 . ILE A 1 38  ? 102.15480 -40.58704 21.76364 1.000 76.02032  ? 39  ILE A HG23 1 
ATOM   576  H HD11 . ILE A 1 38  ? 104.06933 -37.24435 23.54410 1.000 74.74508  ? 39  ILE A HD11 1 
ATOM   577  H HD12 . ILE A 1 38  ? 103.75547 -37.16606 21.98883 1.000 74.74508  ? 39  ILE A HD12 1 
ATOM   578  H HD13 . ILE A 1 38  ? 102.68110 -37.77817 22.98610 1.000 74.74508  ? 39  ILE A HD13 1 
ATOM   579  N N    . THR A 1 39  ? 103.65100 -42.72365 19.72812 1.000 58.85514  ? 40  THR A N    1 
ATOM   580  C CA   . THR A 1 39  ? 103.25720 -43.47313 18.55778 1.000 60.86849  ? 40  THR A CA   1 
ATOM   581  C C    . THR A 1 39  ? 101.75214 -43.37493 18.38441 1.000 54.96616  ? 40  THR A C    1 
ATOM   582  O O    . THR A 1 39  ? 100.99056 -43.50256 19.34894 1.000 53.47705  ? 40  THR A O    1 
ATOM   583  C CB   . THR A 1 39  ? 103.68001 -44.94166 18.66477 1.000 58.66924  ? 40  THR A CB   1 
ATOM   584  O OG1  . THR A 1 39  ? 105.09516 -45.00324 18.83859 1.000 62.22496  ? 40  THR A OG1  1 
ATOM   585  C CG2  . THR A 1 39  ? 103.30224 -45.66937 17.41996 1.000 62.75281  ? 40  THR A CG2  1 
ATOM   586  H H    . THR A 1 39  ? 103.38716 -43.08288 20.46361 1.000 70.69744  ? 40  THR A H    1 
ATOM   587  H HA   . THR A 1 39  ? 103.68641 -43.10111 17.77148 1.000 73.11346  ? 40  THR A HA   1 
ATOM   588  H HB   . THR A 1 39  ? 103.23943 -45.36646 19.41732 1.000 70.47436  ? 40  THR A HB   1 
ATOM   589  H HG1  . THR A 1 39  ? 105.33143 -45.79429 18.99355 1.000 74.74122  ? 40  THR A HG1  1 
ATOM   590  H HG21 . THR A 1 39  ? 103.79512 -46.50268 17.36027 1.000 75.37464  ? 40  THR A HG21 1 
ATOM   591  H HG22 . THR A 1 39  ? 102.35224 -45.86523 17.42549 1.000 75.37464  ? 40  THR A HG22 1 
ATOM   592  H HG23 . THR A 1 39  ? 103.50713 -45.12610 16.64293 1.000 75.37464  ? 40  THR A HG23 1 
ATOM   593  N N    . VAL A 1 40  ? 101.33550 -43.16880 17.13727 1.000 56.55348  ? 41  VAL A N    1 
ATOM   594  C CA   . VAL A 1 40  ? 99.93713  -43.23815 16.73321 1.000 55.50784  ? 41  VAL A CA   1 
ATOM   595  C C    . VAL A 1 40  ? 99.80851  -44.29478 15.64905 1.000 54.87334  ? 41  VAL A C    1 
ATOM   596  O O    . VAL A 1 40  ? 100.51908 -44.24431 14.64158 1.000 55.72625  ? 41  VAL A O    1 
ATOM   597  C CB   . VAL A 1 40  ? 99.42137  -41.87988 16.22744 1.000 51.81573  ? 41  VAL A CB   1 
ATOM   598  C CG1  . VAL A 1 40  ? 97.95220  -41.96644 15.86617 1.000 47.38674  ? 41  VAL A CG1  1 
ATOM   599  C CG2  . VAL A 1 40  ? 99.68019  -40.81954 17.26425 1.000 52.83744  ? 41  VAL A CG2  1 
ATOM   600  H H    . VAL A 1 40  ? 101.86484 -42.98070 16.48610 1.000 67.93544  ? 41  VAL A H    1 
ATOM   601  H HA   . VAL A 1 40  ? 99.39814  -43.50628 17.49380 1.000 66.68068  ? 41  VAL A HA   1 
ATOM   602  H HB   . VAL A 1 40  ? 99.89691  -41.63002 15.41977 1.000 62.25014  ? 41  VAL A HB   1 
ATOM   603  H HG11 . VAL A 1 40  ? 97.62331  -41.07620 15.66566 1.000 56.93536  ? 41  VAL A HG11 1 
ATOM   604  H HG12 . VAL A 1 40  ? 97.85111  -42.53907 15.08979 1.000 56.93536  ? 41  VAL A HG12 1 
ATOM   605  H HG13 . VAL A 1 40  ? 97.46368  -42.33817 16.61722 1.000 56.93536  ? 41  VAL A HG13 1 
ATOM   606  H HG21 . VAL A 1 40  ? 99.25603  -39.99349 16.98387 1.000 63.47620  ? 41  VAL A HG21 1 
ATOM   607  H HG22 . VAL A 1 40  ? 99.30997  -41.11017 18.11241 1.000 63.47620  ? 41  VAL A HG22 1 
ATOM   608  H HG23 . VAL A 1 40  ? 100.63744 -40.68768 17.34898 1.000 63.47620  ? 41  VAL A HG23 1 
ATOM   609  N N    . MET A 1 41  ? 98.90769  -45.24853 15.86071 1.000 57.22954  ? 42  MET A N    1 
ATOM   610  C CA   . MET A 1 41  ? 98.60862  -46.29760 14.89371 1.000 55.90576  ? 42  MET A CA   1 
ATOM   611  C C    . MET A 1 41  ? 97.13660  -46.19465 14.53167 1.000 57.04160  ? 42  MET A C    1 
ATOM   612  O O    . MET A 1 41  ? 96.27710  -46.09553 15.42160 1.000 56.35541  ? 42  MET A O    1 
ATOM   613  C CB   . MET A 1 41  ? 98.89635  -47.68446 15.44921 1.000 54.71223  ? 42  MET A CB   1 
ATOM   614  C CG   . MET A 1 41  ? 100.32420 -47.85655 15.90760 1.000 75.07722  ? 42  MET A CG   1 
ATOM   615  S SD   . MET A 1 41  ? 100.71713 -49.61160 16.19998 1.000 75.35483  ? 42  MET A SD   1 
ATOM   616  C CE   . MET A 1 41  ? 99.46288  -50.02443 17.42739 1.000 95.02648  ? 42  MET A CE   1 
ATOM   617  H H    . MET A 1 41  ? 98.44194  -45.31029 16.58104 1.000 68.74671  ? 42  MET A H    1 
ATOM   618  H HA   . MET A 1 41  ? 99.16620  -46.17562 14.10942 1.000 67.15818  ? 42  MET A HA   1 
ATOM   619  H HB2  . MET A 1 41  ? 98.31702  -47.84415 16.21063 1.000 65.72594  ? 42  MET A HB2  1 
ATOM   620  H HB3  . MET A 1 41  ? 98.72361  -48.34193 14.75725 1.000 65.72594  ? 42  MET A HB3  1 
ATOM   621  H HG2  . MET A 1 41  ? 100.92439 -47.51789 15.22497 1.000 90.16393  ? 42  MET A HG2  1 
ATOM   622  H HG3  . MET A 1 41  ? 100.45682 -47.37074 16.73663 1.000 90.16393  ? 42  MET A HG3  1 
ATOM   623  H HE1  . MET A 1 41  ? 99.75953  -50.79604 17.93485 1.000 114.10304 ? 42  MET A HE1  1 
ATOM   624  H HE2  . MET A 1 41  ? 99.33930  -49.26644 18.01991 1.000 114.10304 ? 42  MET A HE2  1 
ATOM   625  H HE3  . MET A 1 41  ? 98.63067  -50.22777 16.97244 1.000 114.10304 ? 42  MET A HE3  1 
ATOM   626  N N    . MET A 1 42  ? 96.84606  -46.19624 13.23348 1.000 61.93143  ? 43  MET A N    1 
ATOM   627  C CA   . MET A 1 42  ? 95.48112  -46.05560 12.72814 1.000 63.03779  ? 43  MET A CA   1 
ATOM   628  C C    . MET A 1 42  ? 95.06590  -47.37753 12.11792 1.000 57.07441  ? 43  MET A C    1 
ATOM   629  O O    . MET A 1 42  ? 95.81849  -47.96420 11.33621 1.000 61.98025  ? 43  MET A O    1 
ATOM   630  C CB   . MET A 1 42  ? 95.36533  -44.93027 11.69963 1.000 51.60752  ? 43  MET A CB   1 
ATOM   631  C CG   . MET A 1 42  ? 96.06950  -43.69506 12.22423 1.000 62.04743  ? 43  MET A CG   1 
ATOM   632  S SD   . MET A 1 42  ? 95.50713  -42.16826 11.45771 1.000 70.11823  ? 43  MET A SD   1 
ATOM   633  C CE   . MET A 1 42  ? 97.07178  -41.23751 11.57496 1.000 64.65010  ? 43  MET A CE   1 
ATOM   634  H H    . MET A 1 42  ? 97.43491  -46.27914 12.61220 1.000 74.38899  ? 43  MET A H    1 
ATOM   635  H HA   . MET A 1 42  ? 94.88753  -45.82596 13.46014 1.000 75.71661  ? 43  MET A HA   1 
ATOM   636  H HB2  . MET A 1 42  ? 95.78375  -45.20131 10.86755 1.000 62.00029  ? 43  MET A HB2  1 
ATOM   637  H HB3  . MET A 1 42  ? 94.43091  -44.71892 11.54765 1.000 62.00029  ? 43  MET A HB3  1 
ATOM   638  H HG2  . MET A 1 42  ? 95.90917  -43.62467 13.17830 1.000 74.52819  ? 43  MET A HG2  1 
ATOM   639  H HG3  . MET A 1 42  ? 97.02046  -43.78029 12.05303 1.000 74.52819  ? 43  MET A HG3  1 
ATOM   640  H HE1  . MET A 1 42  ? 96.96209  -40.37896 11.13705 1.000 77.65139  ? 43  MET A HE1  1 
ATOM   641  H HE2  . MET A 1 42  ? 97.29163  -41.10596 12.51051 1.000 77.65139  ? 43  MET A HE2  1 
ATOM   642  H HE3  . MET A 1 42  ? 97.77417  -41.74426 11.13820 1.000 77.65139  ? 43  MET A HE3  1 
ATOM   643  N N    . HIS A 1 43  ? 93.91651  -47.86512 12.54394 1.000 58.95018  ? 44  HIS A N    1 
ATOM   644  C CA   . HIS A 1 43  ? 93.33645  -49.12621 12.10127 1.000 58.63830  ? 44  HIS A CA   1 
ATOM   645  C C    . HIS A 1 43  ? 92.11904  -48.77252 11.27158 1.000 62.32325  ? 44  HIS A C    1 
ATOM   646  O O    . HIS A 1 43  ? 91.12782  -48.25396 11.79802 1.000 58.91292  ? 44  HIS A O    1 
ATOM   647  C CB   . HIS A 1 43  ? 92.97380  -50.00365 13.28617 1.000 65.29782  ? 44  HIS A CB   1 
ATOM   648  C CG   . HIS A 1 43  ? 94.17362  -50.47960 14.05028 1.000 81.19659  ? 44  HIS A CG   1 
ATOM   649  N ND1  . HIS A 1 43  ? 94.16482  -50.72919 15.41140 1.000 85.46855  ? 44  HIS A ND1  1 
ATOM   650  C CD2  . HIS A 1 43  ? 95.43142  -50.76273 13.62733 1.000 86.12244  ? 44  HIS A CD2  1 
ATOM   651  C CE1  . HIS A 1 43  ? 95.35649  -51.16069 15.79016 1.000 84.16128  ? 44  HIS A CE1  1 
ATOM   652  N NE2  . HIS A 1 43  ? 96.14564  -51.18293 14.72820 1.000 90.97568  ? 44  HIS A NE2  1 
ATOM   653  H H    . HIS A 1 43  ? 93.42316  -47.46347 13.12263 1.000 70.81148  ? 44  HIS A H    1 
ATOM   654  H HA   . HIS A 1 43  ? 93.96586  -49.62219 11.55469 1.000 70.43723  ? 44  HIS A HA   1 
ATOM   655  H HB2  . HIS A 1 43  ? 92.41349  -49.49629 13.89406 1.000 78.42866  ? 44  HIS A HB2  1 
ATOM   656  H HB3  . HIS A 1 43  ? 92.49420  -50.78346 12.96558 1.000 78.42866  ? 44  HIS A HB3  1 
ATOM   657  H HD2  . HIS A 1 43  ? 95.75148  -50.68730 12.75740 1.000 103.41819 ? 44  HIS A HD2  1 
ATOM   658  H HE1  . HIS A 1 43  ? 95.59809  -51.40617 16.65403 1.000 101.06480 ? 44  HIS A HE1  1 
ATOM   659  H HE2  . HIS A 1 43  ? 96.97190  -51.42142 14.72554 1.000 109.24208 ? 44  HIS A HE2  1 
ATOM   660  N N    . GLU A 1 44  ? 92.21581  -49.03222 9.97397  1.000 71.44462  ? 45  GLU A N    1 
ATOM   661  C CA   . GLU A 1 44  ? 91.20145  -48.67502 8.99503  1.000 69.24280  ? 45  GLU A CA   1 
ATOM   662  C C    . GLU A 1 44  ? 90.33083  -49.89988 8.73940  1.000 59.73018  ? 45  GLU A C    1 
ATOM   663  O O    . GLU A 1 44  ? 90.83835  -51.00972 8.57052  1.000 53.52887  ? 45  GLU A O    1 
ATOM   664  C CB   . GLU A 1 44  ? 91.87619  -48.19994 7.70620  1.000 74.73635  ? 45  GLU A CB   1 
ATOM   665  C CG   . GLU A 1 44  ? 91.08378  -47.18688 6.90657  1.000 79.18124  ? 45  GLU A CG   1 
ATOM   666  C CD   . GLU A 1 44  ? 91.82705  -46.69915 5.64411  1.000 76.96125  ? 45  GLU A CD   1 
ATOM   667  O OE1  . GLU A 1 44  ? 92.29031  -47.54556 4.84699  1.000 76.16725  ? 45  GLU A OE1  1 
ATOM   668  O OE2  . GLU A 1 44  ? 91.94372  -45.45973 5.48538  1.000 74.94919  ? 45  GLU A OE2  1 
ATOM   669  H H    . GLU A 1 44  ? 92.89052  -49.43257 9.62170  1.000 85.80481  ? 45  GLU A H    1 
ATOM   670  H HA   . GLU A 1 44  ? 90.63164  -47.95709 9.31250  1.000 83.16263  ? 45  GLU A HA   1 
ATOM   671  H HB2  . GLU A 1 44  ? 92.72441  -47.78971 7.93670  1.000 89.75489  ? 45  GLU A HB2  1 
ATOM   672  H HB3  . GLU A 1 44  ? 92.02437  -48.96992 7.13517  1.000 89.75489  ? 45  GLU A HB3  1 
ATOM   673  H HG2  . GLU A 1 44  ? 90.24891  -47.59192 6.62402  1.000 95.08876  ? 45  GLU A HG2  1 
ATOM   674  H HG3  . GLU A 1 44  ? 90.90532  -46.41437 7.46540  1.000 95.08876  ? 45  GLU A HG3  1 
ATOM   675  N N    . MET A 1 45  ? 89.01997  -49.71158 8.71704  1.000 61.05476  ? 46  MET A N    1 
ATOM   676  C CA   . MET A 1 45  ? 88.10214  -50.83047 8.54925  1.000 66.64637  ? 46  MET A CA   1 
ATOM   677  C C    . MET A 1 45  ? 87.20023  -50.64698 7.33342  1.000 70.23607  ? 46  MET A C    1 
ATOM   678  O O    . MET A 1 45  ? 86.62194  -49.57547 7.15308  1.000 67.42771  ? 46  MET A O    1 
ATOM   679  C CB   . MET A 1 45  ? 87.25453  -50.97648 9.81380  1.000 64.76339  ? 46  MET A CB   1 
ATOM   680  C CG   . MET A 1 45  ? 87.96630  -51.62663 11.00362 1.000 79.09157  ? 46  MET A CG   1 
ATOM   681  S SD   . MET A 1 45  ? 86.87201  -51.59983 12.44559 1.000 71.77596  ? 46  MET A SD   1 
ATOM   682  C CE   . MET A 1 45  ? 86.40910  -49.89485 12.63367 1.000 84.45537  ? 46  MET A CE   1 
ATOM   683  H H    . MET A 1 45  ? 88.63759  -48.94543 8.79703  1.000 73.33698  ? 46  MET A H    1 
ATOM   684  H HA   . MET A 1 45  ? 88.61893  -51.63648 8.39376  1.000 80.04690  ? 46  MET A HA   1 
ATOM   685  H HB2  . MET A 1 45  ? 86.96831  -50.09316 10.09436 1.000 77.78733  ? 46  MET A HB2  1 
ATOM   686  H HB3  . MET A 1 45  ? 86.48214  -51.52419 9.60325  1.000 77.78733  ? 46  MET A HB3  1 
ATOM   687  H HG2  . MET A 1 45  ? 88.18551  -52.54768 10.79263 1.000 94.98115  ? 46  MET A HG2  1 
ATOM   688  H HG3  . MET A 1 45  ? 88.77450  -51.13293 11.21332 1.000 94.98115  ? 46  MET A HG3  1 
ATOM   689  H HE1  . MET A 1 45  ? 85.86983  -49.80051 13.43440 1.000 101.41771 ? 46  MET A HE1  1 
ATOM   690  H HE2  . MET A 1 45  ? 87.21215  -49.35620 12.71033 1.000 101.41771 ? 46  MET A HE2  1 
ATOM   691  H HE3  . MET A 1 45  ? 85.89850  -49.61867 11.85655 1.000 101.41771 ? 46  MET A HE3  1 
ATOM   692  N N    . GLN A 1 46  ? 87.04733  -51.70813 6.53364  1.000 70.50437  ? 47  GLN A N    1 
ATOM   693  C CA   . GLN A 1 46  ? 86.01727  -51.75470 5.49960  1.000 72.27187  ? 47  GLN A CA   1 
ATOM   694  C C    . GLN A 1 46  ? 84.63301  -51.76277 6.15403  1.000 69.84537  ? 47  GLN A C    1 
ATOM   695  O O    . GLN A 1 46  ? 84.46506  -52.15878 7.31014  1.000 70.62484  ? 47  GLN A O    1 
ATOM   696  C CB   . GLN A 1 46  ? 86.20105  -52.98555 4.61265  1.000 78.10053  ? 47  GLN A CB   1 
ATOM   697  C CG   . GLN A 1 46  ? 87.63485  -53.18278 4.03711  1.000 78.66155  ? 47  GLN A CG   1 
ATOM   698  C CD   . GLN A 1 46  ? 87.64964  -53.48711 2.53619  1.000 114.92443 ? 47  GLN A CD   1 
ATOM   699  O OE1  . GLN A 1 46  ? 87.53036  -54.64500 2.11176  1.000 113.66458 ? 47  GLN A OE1  1 
ATOM   700  N NE2  . GLN A 1 46  ? 87.80589  -52.44026 1.72553  1.000 107.46234 ? 47  GLN A NE2  1 
ATOM   701  H H    . GLN A 1 46  ? 87.53213  -52.41742 6.57207  1.000 84.67651  ? 47  GLN A H    1 
ATOM   702  H HA   . GLN A 1 46  ? 86.08233  -50.97468 4.92669  1.000 86.79751  ? 47  GLN A HA   1 
ATOM   703  H HB2  . GLN A 1 46  ? 85.98801  -53.77409 5.13582  1.000 93.79190  ? 47  GLN A HB2  1 
ATOM   704  H HB3  . GLN A 1 46  ? 85.59410  -52.91317 3.85948  1.000 93.79190  ? 47  GLN A HB3  1 
ATOM   705  H HG2  . GLN A 1 46  ? 88.14527  -52.37057 4.18097  1.000 94.46513  ? 47  GLN A HG2  1 
ATOM   706  H HG3  . GLN A 1 46  ? 88.05757  -53.92583 4.49546  1.000 94.46513  ? 47  GLN A HG3  1 
ATOM   707  H HE21 . GLN A 1 46  ? 87.89116  -51.65038 2.05480  1.000 129.02608 ? 47  GLN A HE21 1 
ATOM   708  H HE22 . GLN A 1 46  ? 87.82140  -52.55487 0.87334  1.000 129.02608 ? 47  GLN A HE22 1 
ATOM   709  N N    . ALA A 1 47  ? 83.63286  -51.29738 5.41339  1.000 71.42695  ? 48  ALA A N    1 
ATOM   710  C CA   . ALA A 1 47  ? 82.29057  -51.20258 5.97409  1.000 71.62369  ? 48  ALA A CA   1 
ATOM   711  C C    . ALA A 1 47  ? 81.79653  -52.55309 6.45665  1.000 76.22354  ? 48  ALA A C    1 
ATOM   712  O O    . ALA A 1 47  ? 81.13744  -52.64504 7.50143  1.000 73.13441  ? 48  ALA A O    1 
ATOM   713  C CB   . ALA A 1 47  ? 81.31182  -50.64458 4.94799  1.000 80.78037  ? 48  ALA A CB   1 
ATOM   714  H H    . ALA A 1 47  ? 83.70273  -51.03429 4.59761  1.000 85.78360  ? 48  ALA A H    1 
ATOM   715  H HA   . ALA A 1 47  ? 82.32732  -50.59120 6.72626  1.000 86.01969  ? 48  ALA A HA   1 
ATOM   716  H HB1  . ALA A 1 47  ? 80.44202  -50.54138 5.36477  1.000 97.00771  ? 48  ALA A HB1  1 
ATOM   717  H HB2  . ALA A 1 47  ? 81.63481  -49.78369 4.63905  1.000 97.00771  ? 48  ALA A HB2  1 
ATOM   718  H HB3  . ALA A 1 47  ? 81.25012  -51.26177 4.20222  1.000 97.00771  ? 48  ALA A HB3  1 
ATOM   719  N N    . ALA A 1 48  ? 82.10413  -53.61262 5.70929  1.000 76.13286  ? 49  ALA A N    1 
ATOM   720  C CA   . ALA A 1 48  ? 81.67203  -54.94133 6.10405  1.000 78.71212  ? 49  ALA A CA   1 
ATOM   721  C C    . ALA A 1 48  ? 82.27294  -55.40141 7.42986  1.000 73.48572  ? 49  ALA A C    1 
ATOM   722  O O    . ALA A 1 48  ? 81.80101  -56.40308 7.97614  1.000 65.22515  ? 49  ALA A O    1 
ATOM   723  C CB   . ALA A 1 48  ? 82.03344  -55.96594 5.01820  1.000 77.40224  ? 49  ALA A CB   1 
ATOM   724  H H    . ALA A 1 48  ? 82.55681  -53.58431 4.97862  1.000 91.43070  ? 49  ALA A H    1 
ATOM   725  H HA   . ALA A 1 48  ? 80.70703  -54.91801 6.19963  1.000 94.52581  ? 49  ALA A HA   1 
ATOM   726  H HB1  . ALA A 1 48  ? 81.72580  -56.84278 5.29644  1.000 92.95395  ? 49  ALA A HB1  1 
ATOM   727  H HB2  . ALA A 1 48  ? 81.60119  -55.71186 4.18783  1.000 92.95395  ? 49  ALA A HB2  1 
ATOM   728  H HB3  . ALA A 1 48  ? 82.99624  -55.97514 4.90059  1.000 92.95395  ? 49  ALA A HB3  1 
ATOM   729  N N    . ASP A 1 49  ? 83.28914  -54.70945 7.95078  1.000 71.27486  ? 50  ASP A N    1 
ATOM   730  C CA   . ASP A 1 49  ? 84.04657  -55.16647 9.10895  1.000 68.59500  ? 50  ASP A CA   1 
ATOM   731  C C    . ASP A 1 49  ? 83.72199  -54.36811 10.37675 1.000 62.51681  ? 50  ASP A C    1 
ATOM   732  O O    . ASP A 1 49  ? 84.36671  -54.55709 11.41552 1.000 60.75020  ? 50  ASP A O    1 
ATOM   733  C CB   . ASP A 1 49  ? 85.54812  -55.09647 8.82701  1.000 66.17976  ? 50  ASP A CB   1 
ATOM   734  C CG   . ASP A 1 49  ? 85.97941  -56.01445 7.72158  1.000 66.86013  ? 50  ASP A CG   1 
ATOM   735  O OD1  . ASP A 1 49  ? 87.04911  -55.77498 7.11458  1.000 68.25152  ? 50  ASP A OD1  1 
ATOM   736  O OD2  . ASP A 1 49  ? 85.24613  -56.98417 7.44887  1.000 70.13750  ? 50  ASP A OD2  1 
ATOM   737  H H    . ASP A 1 49  ? 83.56199  -53.95513 7.64070  1.000 85.60110  ? 50  ASP A H    1 
ATOM   738  H HA   . ASP A 1 49  ? 83.81536  -56.09430 9.27193  1.000 82.38526  ? 50  ASP A HA   1 
ATOM   739  H HB2  . ASP A 1 49  ? 85.77879  -54.18999 8.57013  1.000 79.48698  ? 50  ASP A HB2  1 
ATOM   740  H HB3  . ASP A 1 49  ? 86.03168  -55.34707 9.62967  1.000 79.48698  ? 50  ASP A HB3  1 
ATOM   741  N N    . TYR A 1 50  ? 82.75106  -53.47789 10.30826 1.000 62.87130  ? 51  TYR A N    1 
ATOM   742  C CA   . TYR A 1 50  ? 82.40924  -52.59195 11.39829 1.000 65.33376  ? 51  TYR A CA   1 
ATOM   743  C C    . TYR A 1 50  ? 80.90120  -52.58518 11.54611 1.000 66.05921  ? 51  TYR A C    1 
ATOM   744  O O    . TYR A 1 50  ? 80.15528  -52.62412 10.56207 1.000 72.97444  ? 51  TYR A O    1 
ATOM   745  C CB   . TYR A 1 50  ? 82.91760  -51.20383 11.15020 1.000 66.25133  ? 51  TYR A CB   1 
ATOM   746  C CG   . TYR A 1 50  ? 82.41477  -50.20753 12.11577 1.000 67.17111  ? 51  TYR A CG   1 
ATOM   747  C CD1  . TYR A 1 50  ? 83.16896  -49.87776 13.25259 1.000 71.33644  ? 51  TYR A CD1  1 
ATOM   748  C CD2  . TYR A 1 50  ? 81.19316  -49.56928 11.90844 1.000 70.33336  ? 51  TYR A CD2  1 
ATOM   749  C CE1  . TYR A 1 50  ? 82.71277  -48.93547 14.16241 1.000 76.08349  ? 51  TYR A CE1  1 
ATOM   750  C CE2  . TYR A 1 50  ? 80.72767  -48.62559 12.80114 1.000 77.78666  ? 51  TYR A CE2  1 
ATOM   751  C CZ   . TYR A 1 50  ? 81.49245  -48.31770 13.92532 1.000 80.47481  ? 51  TYR A CZ   1 
ATOM   752  O OH   . TYR A 1 50  ? 81.03340  -47.38894 14.81134 1.000 84.98917  ? 51  TYR A OH   1 
ATOM   753  H H    . TYR A 1 50  ? 82.25762  -53.36484 9.61303  1.000 75.51683  ? 51  TYR A H    1 
ATOM   754  H HA   . TYR A 1 50  ? 82.80371  -52.90247 12.22827 1.000 78.47178  ? 51  TYR A HA   1 
ATOM   755  H HB2  . TYR A 1 50  ? 83.88582  -51.21084 11.20852 1.000 79.57286  ? 51  TYR A HB2  1 
ATOM   756  H HB3  . TYR A 1 50  ? 82.64065  -50.92368 10.26379 1.000 79.57286  ? 51  TYR A HB3  1 
ATOM   757  H HD1  . TYR A 1 50  ? 83.98626  -50.29705 13.39790 1.000 85.67500  ? 51  TYR A HD1  1 
ATOM   758  H HD2  . TYR A 1 50  ? 80.68534  -49.78212 11.15896 1.000 84.47130  ? 51  TYR A HD2  1 
ATOM   759  H HE1  . TYR A 1 50  ? 83.21422  -48.72188 14.91595 1.000 91.37146  ? 51  TYR A HE1  1 
ATOM   760  H HE2  . TYR A 1 50  ? 79.91375  -48.20019 12.65463 1.000 93.41526  ? 51  TYR A HE2  1 
ATOM   761  H HH   . TYR A 1 50  ? 80.26106  -47.14090 14.59321 1.000 102.05827 ? 51  TYR A HH   1 
ATOM   762  N N    . MET A 1 51  ? 80.44638  -52.54572 12.78153 1.000 64.86340  ? 52  MET A N    1 
ATOM   763  C CA   . MET A 1 51  ? 79.01590  -52.62788 13.02605 1.000 68.14142  ? 52  MET A CA   1 
ATOM   764  C C    . MET A 1 51  ? 78.74521  -51.95202 14.35788 1.000 66.80538  ? 52  MET A C    1 
ATOM   765  O O    . MET A 1 51  ? 79.47389  -52.17686 15.33039 1.000 65.76222  ? 52  MET A O    1 
ATOM   766  C CB   . MET A 1 51  ? 78.57120  -54.08888 13.00045 1.000 68.52624  ? 52  MET A CB   1 
ATOM   767  C CG   . MET A 1 51  ? 77.09264  -54.31685 13.19060 1.000 82.10251  ? 52  MET A CG   1 
ATOM   768  S SD   . MET A 1 51  ? 76.60176  -56.07398 13.21380 1.000 71.21588  ? 52  MET A SD   1 
ATOM   769  C CE   . MET A 1 51  ? 77.17170  -56.61495 11.58314 1.000 66.38037  ? 52  MET A CE   1 
ATOM   770  H H    . MET A 1 51  ? 80.93439  -52.47306 13.48592 1.000 77.90735  ? 52  MET A H    1 
ATOM   771  H HA   . MET A 1 51  ? 78.50423  -52.16477 12.34441 1.000 81.84097  ? 52  MET A HA   1 
ATOM   772  H HB2  . MET A 1 51  ? 78.81417  -54.46731 12.14100 1.000 82.30275  ? 52  MET A HB2  1 
ATOM   773  H HB3  . MET A 1 51  ? 79.03068  -54.56075 13.71257 1.000 82.30275  ? 52  MET A HB3  1 
ATOM   774  H HG2  . MET A 1 51  ? 76.82480  -53.92605 14.03702 1.000 98.59428  ? 52  MET A HG2  1 
ATOM   775  H HG3  . MET A 1 51  ? 76.61648  -53.88865 12.46202 1.000 98.59428  ? 52  MET A HG3  1 
ATOM   776  H HE1  . MET A 1 51  ? 76.95351  -57.55299 11.46752 1.000 79.72771  ? 52  MET A HE1  1 
ATOM   777  H HE2  . MET A 1 51  ? 76.72804  -56.08574 10.90196 1.000 79.72771  ? 52  MET A HE2  1 
ATOM   778  H HE3  . MET A 1 51  ? 78.13185  -56.48925 11.52647 1.000 79.72771  ? 52  MET A HE3  1 
ATOM   779  N N    . ARG A 1 52  ? 77.75400  -51.06565 14.36853 1.000 64.29691  ? 53  ARG A N    1 
ATOM   780  C CA   . ARG A 1 52  ? 77.25716  -50.44404 15.58292 1.000 74.76042  ? 53  ARG A CA   1 
ATOM   781  C C    . ARG A 1 52  ? 75.74218  -50.48531 15.45231 1.000 81.86957  ? 53  ARG A C    1 
ATOM   782  O O    . ARG A 1 52  ? 75.19574  -50.13441 14.40230 1.000 83.98862  ? 53  ARG A O    1 
ATOM   783  C CB   . ARG A 1 52  ? 77.76532  -49.00803 15.77875 1.000 82.26244  ? 53  ARG A CB   1 
ATOM   784  C CG   . ARG A 1 52  ? 77.59338  -48.51970 17.23273 1.000 86.92294  ? 53  ARG A CG   1 
ATOM   785  C CD   . ARG A 1 52  ? 78.18872  -47.13568 17.49381 1.000 79.96831  ? 53  ARG A CD   1 
ATOM   786  N NE   . ARG A 1 52  ? 79.61617  -47.08275 17.16461 1.000 104.76447 ? 53  ARG A NE   1 
ATOM   787  C CZ   . ARG A 1 52  ? 80.57721  -46.64394 17.97210 1.000 96.98935  ? 53  ARG A CZ   1 
ATOM   788  N NH1  . ARG A 1 52  ? 80.29674  -46.12165 19.14892 1.000 97.77734  ? 53  ARG A NH1  1 
ATOM   789  N NH2  . ARG A 1 52  ? 81.84755  -46.69372 17.56530 1.000 87.75580  ? 53  ARG A NH2  1 
ATOM   790  H H    . ARG A 1 52  ? 77.34259  -50.80221 13.66076 1.000 77.22756  ? 53  ARG A H    1 
ATOM   791  H HA   . ARG A 1 52  ? 77.55288  -50.92266 16.37310 1.000 89.78377  ? 53  ARG A HA   1 
ATOM   792  H HB2  . ARG A 1 52  ? 78.70902  -48.97221 15.55730 1.000 98.78619  ? 53  ARG A HB2  1 
ATOM   793  H HB3  . ARG A 1 52  ? 77.26558  -48.41251 15.19864 1.000 98.78619  ? 53  ARG A HB3  1 
ATOM   794  H HG2  . ARG A 1 52  ? 76.64632  -48.47695 17.43801 1.000 104.37879 ? 53  ARG A HG2  1 
ATOM   795  H HG3  . ARG A 1 52  ? 78.03370  -49.14713 17.82716 1.000 104.37879 ? 53  ARG A HG3  1 
ATOM   796  H HD2  . ARG A 1 52  ? 77.72692  -46.48095 16.94701 1.000 96.03323  ? 53  ARG A HD2  1 
ATOM   797  H HD3  . ARG A 1 52  ? 78.08571  -46.91557 18.43288 1.000 96.03323  ? 53  ARG A HD3  1 
ATOM   798  H HE   . ARG A 1 52  ? 79.85156  -47.35831 16.38470 1.000 125.78864 ? 53  ARG A HE   1 
ATOM   799  H HH11 . ARG A 1 52  ? 79.47903  -46.05943 19.40790 1.000 117.40407 ? 53  ARG A HH11 1 
ATOM   800  H HH12 . ARG A 1 52  ? 80.93141  -45.84300 19.65798 1.000 117.40407 ? 53  ARG A HH12 1 
ATOM   801  H HH21 . ARG A 1 52  ? 82.03801  -47.00741 16.78753 1.000 105.37823 ? 53  ARG A HH21 1 
ATOM   802  H HH22 . ARG A 1 52  ? 82.47554  -46.41209 18.08097 1.000 105.37823 ? 53  ARG A HH22 1 
ATOM   803  N N    . GLY A 1 53  ? 75.06202  -50.91835 16.49864 1.000 86.58071  ? 54  GLY A N    1 
ATOM   804  C CA   . GLY A 1 53  ? 73.63777  -51.10341 16.38303 1.000 91.79618  ? 54  GLY A CA   1 
ATOM   805  C C    . GLY A 1 53  ? 73.26963  -52.20834 15.42597 1.000 84.64698  ? 54  GLY A C    1 
ATOM   806  O O    . GLY A 1 53  ? 72.20124  -52.16112 14.81913 1.000 85.13748  ? 54  GLY A O    1 
ATOM   807  H H    . GLY A 1 53  ? 75.39774  -51.10682 17.26764 1.000 103.96811 ? 54  GLY A H    1 
ATOM   808  H HA2  . GLY A 1 53  ? 73.27243  -51.32105 17.25484 1.000 110.22668 ? 54  GLY A HA2  1 
ATOM   809  H HA3  . GLY A 1 53  ? 73.23350  -50.27993 16.06783 1.000 110.22668 ? 54  GLY A HA3  1 
ATOM   810  N N    . ALA A 1 54  ? 74.14107  -53.19520 15.24895 1.000 82.58324  ? 55  ALA A N    1 
ATOM   811  C CA   . ALA A 1 54  ? 73.90170  -54.32469 14.35221 1.000 86.54483  ? 55  ALA A CA   1 
ATOM   812  C C    . ALA A 1 54  ? 73.71921  -53.90389 12.88958 1.000 85.99610  ? 55  ALA A C    1 
ATOM   813  O O    . ALA A 1 54  ? 73.28682  -54.71965 12.05621 1.000 76.84908  ? 55  ALA A O    1 
ATOM   814  C CB   . ALA A 1 54  ? 72.68563  -55.13428 14.82101 1.000 76.04747  ? 55  ALA A CB   1 
ATOM   815  H H    . ALA A 1 54  ? 74.90117  -53.23399 15.64938 1.000 99.17115  ? 55  ALA A H    1 
ATOM   816  H HA   . ALA A 1 54  ? 74.68244  -54.89988 14.37479 1.000 103.92506 ? 55  ALA A HA   1 
ATOM   817  H HB1  . ALA A 1 54  ? 72.53802  -55.86822 14.20421 1.000 91.32823  ? 55  ALA A HB1  1 
ATOM   818  H HB2  . ALA A 1 54  ? 72.86005  -55.47970 15.71048 1.000 91.32823  ? 55  ALA A HB2  1 
ATOM   819  H HB3  . ALA A 1 54  ? 71.90790  -54.55482 14.83782 1.000 91.32823  ? 55  ALA A HB3  1 
ATOM   820  N N    . THR A 1 55  ? 74.08319  -52.66954 12.55845 1.000 87.12432  ? 56  THR A N    1 
ATOM   821  C CA   . THR A 1 55  ? 74.05759  -52.15326 11.20314 1.000 86.99448  ? 56  THR A CA   1 
ATOM   822  C C    . THR A 1 55  ? 75.44812  -51.65540 10.80332 1.000 89.82766  ? 56  THR A C    1 
ATOM   823  O O    . THR A 1 55  ? 76.27669  -51.28451 11.64238 1.000 85.79747  ? 56  THR A O    1 
ATOM   824  C CB   . THR A 1 55  ? 73.05988  -50.98586 11.07484 1.000 91.50500  ? 56  THR A CB   1 
ATOM   825  O OG1  . THR A 1 55  ? 73.69724  -49.75956 11.48696 1.000 96.95436  ? 56  THR A OG1  1 
ATOM   826  C CG2  . THR A 1 55  ? 71.82662  -51.21579 11.95613 1.000 86.19252  ? 56  THR A CG2  1 
ATOM   827  H H    . THR A 1 55  ? 74.36041  -52.08976 13.12994 1.000 104.62045 ? 56  THR A H    1 
ATOM   828  H HA   . THR A 1 55  ? 73.79507  -52.86598 10.59980 1.000 104.46465 ? 56  THR A HA   1 
ATOM   829  H HB   . THR A 1 55  ? 72.77080  -50.91919 10.15132 1.000 109.87727 ? 56  THR A HB   1 
ATOM   830  H HG1  . THR A 1 55  ? 73.13648  -49.13427 11.49895 1.000 116.41650 ? 56  THR A HG1  1 
ATOM   831  H HG21 . THR A 1 55  ? 71.18302  -50.50323 11.81853 1.000 103.50229 ? 56  THR A HG21 1 
ATOM   832  H HG22 . THR A 1 55  ? 71.41126  -52.06296 11.73100 1.000 103.50229 ? 56  THR A HG22 1 
ATOM   833  H HG23 . THR A 1 55  ? 72.08497  -51.23044 12.89097 1.000 103.50229 ? 56  THR A HG23 1 
ATOM   834  N N    . ARG A 1 56  ? 75.69182  -51.60266 9.50355  1.000 96.02950  ? 57  ARG A N    1 
ATOM   835  C CA   . ARG A 1 56  ? 76.89223  -50.94485 9.01934  1.000 81.61052  ? 57  ARG A CA   1 
ATOM   836  C C    . ARG A 1 56  ? 76.68987  -49.43949 9.08160  1.000 83.31419  ? 57  ARG A C    1 
ATOM   837  O O    . ARG A 1 56  ? 75.56167  -48.93578 9.10244  1.000 89.79806  ? 57  ARG A O    1 
ATOM   838  C CB   . ARG A 1 56  ? 77.22539  -51.38443 7.60549  1.000 85.29637  ? 57  ARG A CB   1 
ATOM   839  C CG   . ARG A 1 56  ? 77.05404  -52.87964 7.40511  1.000 88.49986  ? 57  ARG A CG   1 
ATOM   840  C CD   . ARG A 1 56  ? 77.93769  -53.39375 6.26514  1.000 95.46511  ? 57  ARG A CD   1 
ATOM   841  N NE   . ARG A 1 56  ? 77.83899  -52.56041 5.06743  1.000 101.17846 ? 57  ARG A NE   1 
ATOM   842  C CZ   . ARG A 1 56  ? 78.22170  -52.94126 3.85370  1.000 100.45078 ? 57  ARG A CZ   1 
ATOM   843  N NH1  . ARG A 1 56  ? 78.68156  -54.16773 3.61620  1.000 125.79651 ? 57  ARG A NH1  1 
ATOM   844  N NH2  . ARG A 1 56  ? 78.13655  -52.07407 2.85262  1.000 126.57261 ? 57  ARG A NH2  1 
ATOM   845  H H    . ARG A 1 56  ? 75.18625  -51.93453 8.89211  1.000 115.30667 ? 57  ARG A H    1 
ATOM   846  H HA   . ARG A 1 56  ? 77.65281  -51.18497 9.57139  1.000 98.00389  ? 57  ARG A HA   1 
ATOM   847  H HB2  . ARG A 1 56  ? 76.63605  -50.92780 6.98495  1.000 102.42691 ? 57  ARG A HB2  1 
ATOM   848  H HB3  . ARG A 1 56  ? 78.14892  -51.15857 7.41320  1.000 102.42691 ? 57  ARG A HB3  1 
ATOM   849  H HG2  . ARG A 1 56  ? 77.30420  -53.34429 8.21900  1.000 106.27110 ? 57  ARG A HG2  1 
ATOM   850  H HG3  . ARG A 1 56  ? 76.12898  -53.07101 7.18479  1.000 106.27110 ? 57  ARG A HG3  1 
ATOM   851  H HD2  . ARG A 1 56  ? 78.86304  -53.39552 6.55603  1.000 114.62940 ? 57  ARG A HD2  1 
ATOM   852  H HD3  . ARG A 1 56  ? 77.66208  -54.29359 6.03013  1.000 114.62940 ? 57  ARG A HD3  1 
ATOM   853  H HE   . ARG A 1 56  ? 77.51096  -51.77024 5.15479  1.000 121.48542 ? 57  ARG A HE   1 
ATOM   854  H HH11 . ARG A 1 56  ? 78.73709  -54.73784 4.25768  1.000 151.02708 ? 57  ARG A HH11 1 
ATOM   855  H HH12 . ARG A 1 56  ? 78.92311  -54.38995 2.82130  1.000 151.02708 ? 57  ARG A HH12 1 
ATOM   856  H HH21 . ARG A 1 56  ? 77.83748  -51.28049 2.99541  1.000 151.95840 ? 57  ARG A HH21 1 
ATOM   857  H HH22 . ARG A 1 56  ? 78.38045  -52.30572 2.06113  1.000 151.95840 ? 57  ARG A HH22 1 
ATOM   858  N N    . ARG A 1 57  ? 77.79840  -48.71756 9.15906  1.000 85.34360  ? 58  ARG A N    1 
ATOM   859  C CA   . ARG A 1 57  ? 77.75828  -47.26860 9.28769  1.000 85.48387  ? 58  ARG A CA   1 
ATOM   860  C C    . ARG A 1 57  ? 78.53131  -46.63255 8.14071  1.000 84.81541  ? 58  ARG A C    1 
ATOM   861  O O    . ARG A 1 57  ? 79.43945  -47.24563 7.54706  1.000 84.85246  ? 58  ARG A O    1 
ATOM   862  C CB   . ARG A 1 57  ? 78.32722  -46.79525 10.62499 1.000 89.76435  ? 58  ARG A CB   1 
ATOM   863  C CG   . ARG A 1 57  ? 77.45808  -47.16674 11.83776 1.000 89.03858  ? 58  ARG A CG   1 
ATOM   864  C CD   . ARG A 1 57  ? 76.01842  -46.66783 11.67151 1.000 102.66574 ? 58  ARG A CD   1 
ATOM   865  N NE   . ARG A 1 57  ? 75.10953  -47.19765 12.68445 1.000 108.78139 ? 58  ARG A NE   1 
ATOM   866  C CZ   . ARG A 1 57  ? 74.97921  -46.69702 13.90894 1.000 115.17964 ? 58  ARG A CZ   1 
ATOM   867  N NH1  . ARG A 1 57  ? 75.71442  -45.67540 14.32316 1.000 126.63815 ? 58  ARG A NH1  1 
ATOM   868  N NH2  . ARG A 1 57  ? 74.08880  -47.23436 14.74309 1.000 101.52837 ? 58  ARG A NH2  1 
ATOM   869  H H    . ARG A 1 57  ? 78.59246  -49.04722 9.13908  1.000 102.48359 ? 58  ARG A H    1 
ATOM   870  H HA   . ARG A 1 57  ? 76.83652  -46.96999 9.24207  1.000 102.65192 ? 58  ARG A HA   1 
ATOM   871  H HB2  . ARG A 1 57  ? 79.20013  -47.19867 10.75221 1.000 107.78849 ? 58  ARG A HB2  1 
ATOM   872  H HB3  . ARG A 1 57  ? 78.40820  -45.82886 10.60427 1.000 107.78849 ? 58  ARG A HB3  1 
ATOM   873  H HG2  . ARG A 1 57  ? 77.43701  -48.13168 11.93438 1.000 106.91756 ? 58  ARG A HG2  1 
ATOM   874  H HG3  . ARG A 1 57  ? 77.83080  -46.76142 12.63632 1.000 106.91756 ? 58  ARG A HG3  1 
ATOM   875  H HD2  . ARG A 1 57  ? 76.01024  -45.70027 11.73977 1.000 123.27016 ? 58  ARG A HD2  1 
ATOM   876  H HD3  . ARG A 1 57  ? 75.68833  -46.94184 10.80153 1.000 123.27016 ? 58  ARG A HD3  1 
ATOM   877  H HE   . ARG A 1 57  ? 74.62706  -47.87807 12.47504 1.000 130.60893 ? 58  ARG A HE   1 
ATOM   878  H HH11 . ARG A 1 57  ? 76.29292  -45.31998 13.79532 1.000 152.03704 ? 58  ARG A HH11 1 
ATOM   879  H HH12 . ARG A 1 57  ? 75.61308  -45.36777 15.11984 1.000 152.03704 ? 58  ARG A HH12 1 
ATOM   880  H HH21 . ARG A 1 57  ? 73.60574  -47.89822 14.48705 1.000 121.90531 ? 58  ARG A HH21 1 
ATOM   881  H HH22 . ARG A 1 57  ? 73.99748  -46.91714 15.53721 1.000 121.90531 ? 58  ARG A HH22 1 
ATOM   882  N N    . THR A 1 58  ? 78.15314  -45.40809 7.82129  1.000 87.25512  ? 59  THR A N    1 
ATOM   883  C CA   . THR A 1 58  ? 78.79377  -44.71116 6.71339  1.000 92.20973  ? 59  THR A CA   1 
ATOM   884  C C    . THR A 1 58  ? 79.56813  -43.53584 7.26142  1.000 88.46313  ? 59  THR A C    1 
ATOM   885  O O    . THR A 1 58  ? 79.02026  -42.73856 8.03568  1.000 84.15271  ? 59  THR A O    1 
ATOM   886  C CB   . THR A 1 58  ? 77.75197  -44.23961 5.69259  1.000 89.54506  ? 59  THR A CB   1 
ATOM   887  O OG1  . THR A 1 58  ? 76.62517  -43.70618 6.39397  1.000 95.87515  ? 59  THR A OG1  1 
ATOM   888  C CG2  . THR A 1 58  ? 77.33623  -45.42875 4.80257  1.000 82.28559  ? 59  THR A CG2  1 
ATOM   889  H H    . THR A 1 58  ? 77.53679  -44.96311 8.22342  1.000 104.77741 ? 59  THR A H    1 
ATOM   890  H HA   . THR A 1 58  ? 79.40460  -45.30516 6.24975  1.000 110.72295 ? 59  THR A HA   1 
ATOM   891  H HB   . THR A 1 58  ? 78.11080  -43.54673 5.11635  1.000 107.52533 ? 59  THR A HB   1 
ATOM   892  H HG1  . THR A 1 58  ? 76.19358  -43.18840 5.89274  1.000 115.12145 ? 59  THR A HG1  1 
ATOM   893  H HG21 . THR A 1 58  ? 76.77024  -45.11906 4.07824  1.000 98.81398  ? 59  THR A HG21 1 
ATOM   894  H HG22 . THR A 1 58  ? 78.12346  -45.85350 4.42740  1.000 98.81398  ? 59  THR A HG22 1 
ATOM   895  H HG23 . THR A 1 58  ? 76.84672  -46.08101 5.32777  1.000 98.81398  ? 59  THR A HG23 1 
ATOM   896  N N    . PRO A 1 59  ? 80.83682  -43.40958 6.90468  1.000 91.77838  ? 60  PRO A N    1 
ATOM   897  C CA   . PRO A 1 59  ? 81.67489  -42.39911 7.56809  1.000 99.15172  ? 60  PRO A CA   1 
ATOM   898  C C    . PRO A 1 59  ? 81.30890  -40.97160 7.14771  1.000 99.70475  ? 60  PRO A C    1 
ATOM   899  O O    . PRO A 1 59  ? 81.04501  -40.67573 5.97234  1.000 91.47370  ? 60  PRO A O    1 
ATOM   900  C CB   . PRO A 1 59  ? 83.10617  -42.77915 7.14464  1.000 92.54592  ? 60  PRO A CB   1 
ATOM   901  C CG   . PRO A 1 59  ? 82.92997  -43.55292 5.82716  1.000 89.39481  ? 60  PRO A CG   1 
ATOM   902  C CD   . PRO A 1 59  ? 81.56198  -44.20660 5.88599  1.000 84.35364  ? 60  PRO A CD   1 
ATOM   903  H HA   . PRO A 1 59  ? 81.59197  -42.47215 8.53177  1.000 119.05333 ? 60  PRO A HA   1 
ATOM   904  H HB2  . PRO A 1 59  ? 83.63580  -41.97777 7.00981  1.000 111.12637 ? 60  PRO A HB2  1 
ATOM   905  H HB3  . PRO A 1 59  ? 83.51580  -43.33709 7.82421  1.000 111.12637 ? 60  PRO A HB3  1 
ATOM   906  H HG2  . PRO A 1 59  ? 82.98087  -42.93626 5.08015  1.000 107.34504 ? 60  PRO A HG2  1 
ATOM   907  H HG3  . PRO A 1 59  ? 83.62542  -44.22479 5.75072  1.000 107.34504 ? 60  PRO A HG3  1 
ATOM   908  H HD2  . PRO A 1 59  ? 81.11725  -44.15148 5.02571  1.000 101.29563 ? 60  PRO A HD2  1 
ATOM   909  H HD3  . PRO A 1 59  ? 81.63534  -45.13338 6.16276  1.000 101.29563 ? 60  PRO A HD3  1 
ATOM   910  N N    . ALA A 1 60  ? 81.27783  -40.09554 8.14476  1.000 107.04023 ? 61  ALA A N    1 
ATOM   911  C CA   . ALA A 1 60  ? 81.13540  -38.66044 7.90640  1.000 100.91949 ? 61  ALA A CA   1 
ATOM   912  C C    . ALA A 1 60  ? 82.37228  -38.13734 7.18296  1.000 93.57254  ? 61  ALA A C    1 
ATOM   913  O O    . ALA A 1 60  ? 83.49901  -38.31015 7.69177  1.000 92.95361  ? 61  ALA A O    1 
ATOM   914  C CB   . ALA A 1 60  ? 80.95051  -37.93973 9.25168  1.000 104.06940 ? 61  ALA A CB   1 
ATOM   915  H H    . ALA A 1 60  ? 81.33760  -40.30492 8.97674  1.000 128.51955 ? 61  ALA A H    1 
ATOM   916  H HA   . ALA A 1 60  ? 80.36146  -38.48269 7.34933  1.000 121.17465 ? 61  ALA A HA   1 
ATOM   917  H HB1  . ALA A 1 60  ? 80.80968  -36.99429 9.08671  1.000 124.95455 ? 61  ALA A HB1  1 
ATOM   918  H HB2  . ALA A 1 60  ? 80.18049  -38.31429 9.70740  1.000 124.95455 ? 61  ALA A HB2  1 
ATOM   919  H HB3  . ALA A 1 60  ? 81.74742  -38.06646 9.78999  1.000 124.95455 ? 61  ALA A HB3  1 
ATOM   920  N N    . PRO A 1 61  ? 82.21613  -37.47597 6.02798  1.000 87.93962  ? 62  PRO A N    1 
ATOM   921  C CA   . PRO A 1 61  ? 83.39794  -37.02689 5.28029  1.000 79.33051  ? 62  PRO A CA   1 
ATOM   922  C C    . PRO A 1 61  ? 84.20637  -36.02353 6.09638  1.000 75.98713  ? 62  PRO A C    1 
ATOM   923  O O    . PRO A 1 61  ? 83.65981  -35.20633 6.84468  1.000 65.85275  ? 62  PRO A O    1 
ATOM   924  C CB   . PRO A 1 61  ? 82.81088  -36.37373 4.03072  1.000 70.76521  ? 62  PRO A CB   1 
ATOM   925  C CG   . PRO A 1 61  ? 81.32640  -36.28086 4.26980  1.000 77.14124  ? 62  PRO A CG   1 
ATOM   926  C CD   . PRO A 1 61  ? 81.01090  -36.71390 5.65251  1.000 77.27281  ? 62  PRO A CD   1 
ATOM   927  H HA   . PRO A 1 61  ? 83.95331  -37.77975 5.02404  1.000 95.26788  ? 62  PRO A HA   1 
ATOM   928  H HB2  . PRO A 1 61  ? 83.19571  -35.49121 3.91259  1.000 84.98951  ? 62  PRO A HB2  1 
ATOM   929  H HB3  . PRO A 1 61  ? 83.00015  -36.92472 3.25516  1.000 84.98951  ? 62  PRO A HB3  1 
ATOM   930  H HG2  . PRO A 1 61  ? 81.04822  -35.36042 4.14210  1.000 92.64075  ? 62  PRO A HG2  1 
ATOM   931  H HG3  . PRO A 1 61  ? 80.87279  -36.85582 3.63374  1.000 92.64075  ? 62  PRO A HG3  1 
ATOM   932  H HD2  . PRO A 1 61  ? 80.88519  -35.95005 6.23700  1.000 92.79864  ? 62  PRO A HD2  1 
ATOM   933  H HD3  . PRO A 1 61  ? 80.22211  -37.27819 5.66976  1.000 92.79864  ? 62  PRO A HD3  1 
ATOM   934  N N    . ALA A 1 62  ? 85.52363  -36.10152 5.94078  1.000 70.21716  ? 63  ALA A N    1 
ATOM   935  C CA   . ALA A 1 62  ? 86.42556  -35.33974 6.77907  1.000 62.48260  ? 63  ALA A CA   1 
ATOM   936  C C    . ALA A 1 62  ? 86.11712  -33.84981 6.70375  1.000 67.09125  ? 63  ALA A C    1 
ATOM   937  O O    . ALA A 1 62  ? 85.61335  -33.33582 5.70793  1.000 63.00789  ? 63  ALA A O    1 
ATOM   938  C CB   . ALA A 1 62  ? 87.88197  -35.58832 6.38376  1.000 54.41637  ? 63  ALA A CB   1 
ATOM   939  H H    . ALA A 1 62  ? 85.91757  -36.59118 5.35372  1.000 84.33186  ? 63  ALA A H    1 
ATOM   940  H HA   . ALA A 1 62  ? 86.30991  -35.62824 7.69793  1.000 75.05039  ? 63  ALA A HA   1 
ATOM   941  H HB1  . ALA A 1 62  ? 88.45669  -35.02453 6.92481  1.000 65.37091  ? 63  ALA A HB1  1 
ATOM   942  H HB2  . ALA A 1 62  ? 88.09574  -36.52204 6.53663  1.000 65.37091  ? 63  ALA A HB2  1 
ATOM   943  H HB3  . ALA A 1 62  ? 87.99565  -35.37236 5.44496  1.000 65.37091  ? 63  ALA A HB3  1 
ATOM   944  N N    . LEU A 1 63  ? 86.38811  -33.17166 7.79017  1.000 71.56183  ? 64  LEU A N    1 
ATOM   945  C CA   . LEU A 1 63  ? 86.41653  -31.72498 7.82191  1.000 68.92810  ? 64  LEU A CA   1 
ATOM   946  C C    . LEU A 1 63  ? 87.67943  -31.22921 7.12866  1.000 65.35099  ? 64  LEU A C    1 
ATOM   947  O O    . LEU A 1 63  ? 88.73910  -31.85825 7.20912  1.000 59.55320  ? 64  LEU A O    1 
ATOM   948  C CB   . LEU A 1 63  ? 86.38363  -31.21875 9.26333  1.000 68.62992  ? 64  LEU A CB   1 
ATOM   949  C CG   . LEU A 1 63  ? 85.00257  -31.19356 9.95954  1.000 68.10905  ? 64  LEU A CG   1 
ATOM   950  C CD1  . LEU A 1 63  ? 85.24447  -30.89077 11.42215 1.000 63.95522  ? 64  LEU A CD1  1 
ATOM   951  C CD2  . LEU A 1 63  ? 84.06467  -30.19902 9.28874  1.000 80.25357  ? 64  LEU A CD2  1 
ATOM   952  H H    . LEU A 1 63  ? 86.56572  -33.53243 8.55037  1.000 85.94547  ? 64  LEU A H    1 
ATOM   953  H HA   . LEU A 1 63  ? 85.64085  -31.36337 7.36533  1.000 82.78498  ? 64  LEU A HA   1 
ATOM   954  H HB2  . LEU A 1 63  ? 86.95950  -31.79033 9.79490  1.000 82.42717  ? 64  LEU A HB2  1 
ATOM   955  H HB3  . LEU A 1 63  ? 86.72161  -30.30955 9.26942  1.000 82.42717  ? 64  LEU A HB3  1 
ATOM   956  H HG   . LEU A 1 63  ? 84.54771  -32.04720 9.88664  1.000 81.80213  ? 64  LEU A HG   1 
ATOM   957  H HD11 . LEU A 1 63  ? 84.39350  -30.88124 11.88762 1.000 76.81753  ? 64  LEU A HD11 1 
ATOM   958  H HD12 . LEU A 1 63  ? 85.81837  -31.57757 11.79611 1.000 76.81753  ? 64  LEU A HD12 1 
ATOM   959  H HD13 . LEU A 1 63  ? 85.67300  -30.02392 11.49852 1.000 76.81753  ? 64  LEU A HD13 1 
ATOM   960  H HD21 . LEU A 1 63  ? 83.19732  -30.24195 9.72091  1.000 96.37556  ? 64  LEU A HD21 1 
ATOM   961  H HD22 . LEU A 1 63  ? 84.43464  -29.30675 9.37748  1.000 96.37556  ? 64  LEU A HD22 1 
ATOM   962  H HD23 . LEU A 1 63  ? 83.97851  -30.42957 8.35049  1.000 96.37556  ? 64  LEU A HD23 1 
ATOM   963  N N    . PRO A 1 64  ? 87.58619  -30.09914 6.45332  1.000 61.70429  ? 65  PRO A N    1 
ATOM   964  C CA   . PRO A 1 64  ? 88.79196  -29.44065 5.94603  1.000 58.55418  ? 65  PRO A CA   1 
ATOM   965  C C    . PRO A 1 64  ? 89.63293  -28.86345 7.07337  1.000 56.08593  ? 65  PRO A C    1 
ATOM   966  O O    . PRO A 1 64  ? 89.11620  -28.48513 8.12549  1.000 58.76111  ? 65  PRO A O    1 
ATOM   967  C CB   . PRO A 1 64  ? 88.24035  -28.30929 5.06380  1.000 57.27197  ? 65  PRO A CB   1 
ATOM   968  C CG   . PRO A 1 64  ? 86.73117  -28.45773 5.08419  1.000 60.04414  ? 65  PRO A CG   1 
ATOM   969  C CD   . PRO A 1 64  ? 86.37622  -29.27888 6.28405  1.000 64.67667  ? 65  PRO A CD   1 
ATOM   970  H HA   . PRO A 1 64  ? 89.31785  -30.05936 5.41542  1.000 70.33629  ? 65  PRO A HA   1 
ATOM   971  H HB2  . PRO A 1 64  ? 88.50572  -27.45144 5.43063  1.000 68.79763  ? 65  PRO A HB2  1 
ATOM   972  H HB3  . PRO A 1 64  ? 88.58227  -28.40415 4.16103  1.000 68.79763  ? 65  PRO A HB3  1 
ATOM   973  H HG2  . PRO A 1 64  ? 86.32357  -27.57953 5.14363  1.000 72.12423  ? 65  PRO A HG2  1 
ATOM   974  H HG3  . PRO A 1 64  ? 86.44201  -28.90344 4.27263  1.000 72.12423  ? 65  PRO A HG3  1 
ATOM   975  H HD2  . PRO A 1 64  ? 86.22077  -28.71797 7.06002  1.000 77.68327  ? 65  PRO A HD2  1 
ATOM   976  H HD3  . PRO A 1 64  ? 85.59794  -29.83208 6.11331  1.000 77.68327  ? 65  PRO A HD3  1 
ATOM   977  N N    . ASP A 1 65  ? 90.94592  -28.79814 6.83194  1.000 53.53898  ? 66  ASP A N    1 
ATOM   978  C CA   . ASP A 1 65  ? 91.88742  -28.08871 7.69906  1.000 59.89764  ? 66  ASP A CA   1 
ATOM   979  C C    . ASP A 1 65  ? 91.33794  -26.70059 8.02998  1.000 57.75388  ? 66  ASP A C    1 
ATOM   980  O O    . ASP A 1 65  ? 91.24333  -25.84132 7.14080  1.000 57.10309  ? 66  ASP A O    1 
ATOM   981  C CB   . ASP A 1 65  ? 93.24929  -28.01578 7.00696  1.000 54.00205  ? 66  ASP A CB   1 
ATOM   982  C CG   . ASP A 1 65  ? 94.33079  -27.44911 7.90599  1.000 61.54730  ? 66  ASP A CG   1 
ATOM   983  O OD1  . ASP A 1 65  ? 93.98944  -26.92422 8.98232  1.000 67.02757  ? 66  ASP A OD1  1 
ATOM   984  O OD2  . ASP A 1 65  ? 95.52697  -27.54476 7.53621  1.000 67.41855  ? 66  ASP A OD2  1 
ATOM   985  H H    . ASP A 1 65  ? 91.32531  -29.16675 6.15386  1.000 64.31804  ? 66  ASP A H    1 
ATOM   986  H HA   . ASP A 1 65  ? 92.01154  -28.55707 8.53938  1.000 71.94844  ? 66  ASP A HA   1 
ATOM   987  H HB2  . ASP A 1 65  ? 93.51739  -28.90917 6.74074  1.000 64.87373  ? 66  ASP A HB2  1 
ATOM   988  H HB3  . ASP A 1 65  ? 93.17754  -27.44448 6.22634  1.000 64.87373  ? 66  ASP A HB3  1 
ATOM   989  N N    . ALA A 1 66  ? 90.93463  -26.49505 9.28948  1.000 56.86579  ? 67  ALA A N    1 
ATOM   990  C CA   . ALA A 1 66  ? 90.29122  -25.23826 9.67528  1.000 55.08911  ? 67  ALA A CA   1 
ATOM   991  C C    . ALA A 1 66  ? 91.24603  -24.05468 9.49495  1.000 53.75764  ? 67  ALA A C    1 
ATOM   992  O O    . ALA A 1 66  ? 90.83176  -22.96191 9.09664  1.000 49.01273  ? 67  ALA A O    1 
ATOM   993  C CB   . ALA A 1 66  ? 89.80643  -25.33026 11.12195 1.000 50.34388  ? 67  ALA A CB   1 
ATOM   994  H H    . ALA A 1 66  ? 91.02127  -27.06111 9.93109  1.000 68.31022  ? 67  ALA A H    1 
ATOM   995  H HA   . ALA A 1 66  ? 89.51862  -25.08672 9.10869  1.000 66.17820  ? 67  ALA A HA   1 
ATOM   996  H HB1  . ALA A 1 66  ? 89.37566  -24.49565 11.36434 1.000 60.48392  ? 67  ALA A HB1  1 
ATOM   997  H HB2  . ALA A 1 66  ? 89.17484  -26.06259 11.19739 1.000 60.48392  ? 67  ALA A HB2  1 
ATOM   998  H HB3  . ALA A 1 66  ? 90.56830  -25.48958 11.70079 1.000 60.48392  ? 67  ALA A HB3  1 
ATOM   999  N N    . ALA A 1 67  ? 92.53506  -24.25741 9.77536  1.000 46.14434  ? 68  ALA A N    1 
ATOM   1000 C CA   . ALA A 1 67  ? 93.48480  -23.15439 9.68076  1.000 50.62426  ? 68  ALA A CA   1 
ATOM   1001 C C    . ALA A 1 67  ? 93.61123  -22.69839 8.23247  1.000 56.14578  ? 68  ALA A C    1 
ATOM   1002 O O    . ALA A 1 67  ? 93.78837  -21.50221 7.94114  1.000 52.95116  ? 68  ALA A O    1 
ATOM   1003 C CB   . ALA A 1 67  ? 94.85322  -23.55986 10.25710 1.000 51.96429  ? 68  ALA A CB   1 
ATOM   1004 H H    . ALA A 1 67  ? 92.87640  -25.00875 10.01740 1.000 55.44447  ? 68  ALA A H    1 
ATOM   1005 H HA   . ALA A 1 67  ? 93.16715  -22.41006 10.21552 1.000 60.82038  ? 68  ALA A HA   1 
ATOM   1006 H HB1  . ALA A 1 67  ? 95.45786  -22.80377 10.19681 1.000 62.42841  ? 68  ALA A HB1  1 
ATOM   1007 H HB2  . ALA A 1 67  ? 94.74062  -23.82020 11.18470 1.000 62.42841  ? 68  ALA A HB2  1 
ATOM   1008 H HB3  . ALA A 1 67  ? 95.20347  -24.30518 9.74453  1.000 62.42841  ? 68  ALA A HB3  1 
ATOM   1009 N N    . ALA A 1 68  ? 93.53207  -23.64380 7.30489  1.000 53.81073  ? 69  ALA A N    1 
ATOM   1010 C CA   . ALA A 1 68  ? 93.63728  -23.27894 5.90379  1.000 54.86254  ? 69  ALA A CA   1 
ATOM   1011 C C    . ALA A 1 68  ? 92.35636  -22.61764 5.42370  1.000 49.12213  ? 69  ALA A C    1 
ATOM   1012 O O    . ALA A 1 68  ? 92.41343  -21.60832 4.74273  1.000 46.17664  ? 69  ALA A O    1 
ATOM   1013 C CB   . ALA A 1 68  ? 93.97553  -24.50053 5.07146  1.000 46.74334  ? 69  ALA A CB   1 
ATOM   1014 H H    . ALA A 1 68  ? 93.42039  -24.48262 7.45820  1.000 64.64415  ? 69  ALA A H    1 
ATOM   1015 H HA   . ALA A 1 68  ? 94.36247  -22.64587 5.78454  1.000 65.90632  ? 69  ALA A HA   1 
ATOM   1016 H HB1  . ALA A 1 68  ? 93.96272  -24.25649 4.13274  1.000 56.16328  ? 69  ALA A HB1  1 
ATOM   1017 H HB2  . ALA A 1 68  ? 94.85850  -24.81672 5.31901  1.000 56.16328  ? 69  ALA A HB2  1 
ATOM   1018 H HB3  . ALA A 1 68  ? 93.31670  -25.19158 5.24260  1.000 56.16328  ? 69  ALA A HB3  1 
ATOM   1019 N N    . THR A 1 69  ? 91.19393  -23.12425 5.80705  1.000 44.18864  ? 70  THR A N    1 
ATOM   1020 C CA   . THR A 1 69  ? 89.96721  -22.37102 5.55980  1.000 47.71572  ? 70  THR A CA   1 
ATOM   1021 C C    . THR A 1 69  ? 90.09128  -20.91134 6.02561  1.000 52.23959  ? 70  THR A C    1 
ATOM   1022 O O    . THR A 1 69  ? 89.71091  -19.98492 5.31123  1.000 50.51479  ? 70  THR A O    1 
ATOM   1023 C CB   . THR A 1 69  ? 88.81566  -23.03729 6.30047  1.000 49.79121  ? 70  THR A CB   1 
ATOM   1024 O OG1  . THR A 1 69  ? 88.80675  -24.42382 5.99279  1.000 59.87000  ? 70  THR A OG1  1 
ATOM   1025 C CG2  . THR A 1 69  ? 87.50658  -22.39411 5.93583  1.000 47.54670  ? 70  THR A CG2  1 
ATOM   1026 H H    . THR A 1 69  ? 91.08696  -23.88085 6.20165  1.000 53.09763  ? 70  THR A H    1 
ATOM   1027 H HA   . THR A 1 69  ? 89.79146  -22.37328 4.60586  1.000 57.33013  ? 70  THR A HA   1 
ATOM   1028 H HB   . THR A 1 69  ? 88.92473  -22.93168 7.25851  1.000 59.82072  ? 70  THR A HB   1 
ATOM   1029 H HG1  . THR A 1 69  ? 88.19046  -24.80785 6.41506  1.000 71.91526  ? 70  THR A HG1  1 
ATOM   1030 H HG21 . THR A 1 69  ? 86.76986  -22.92294 6.28004  1.000 57.12731  ? 70  THR A HG21 1 
ATOM   1031 H HG22 . THR A 1 69  ? 87.45809  -21.50250 6.31474  1.000 57.12731  ? 70  THR A HG22 1 
ATOM   1032 H HG23 . THR A 1 69  ? 87.42519  -22.33111 4.97130  1.000 57.12731  ? 70  THR A HG23 1 
ATOM   1033 N N    . VAL A 1 70  ? 90.56979  -20.69727 7.25556  1.000 51.91390  ? 71  VAL A N    1 
ATOM   1034 C CA   . VAL A 1 70  ? 90.66704  -19.34492 7.80540  1.000 52.02197  ? 71  VAL A CA   1 
ATOM   1035 C C    . VAL A 1 70  ? 91.61295  -18.49850 6.96027  1.000 49.66503  ? 71  VAL A C    1 
ATOM   1036 O O    . VAL A 1 70  ? 91.27058  -17.37987 6.56122  1.000 47.64770  ? 71  VAL A O    1 
ATOM   1037 C CB   . VAL A 1 70  ? 91.11284  -19.40060 9.27873  1.000 53.77357  ? 71  VAL A CB   1 
ATOM   1038 C CG1  . VAL A 1 70  ? 91.63435  -18.01727 9.80854  1.000 49.07289  ? 71  VAL A CG1  1 
ATOM   1039 C CG2  . VAL A 1 70  ? 89.92248  -19.82884 10.12609 1.000 51.30106  ? 71  VAL A CG2  1 
ATOM   1040 H H    . VAL A 1 70  ? 90.84289  -21.31488 7.78807  1.000 62.36794  ? 71  VAL A H    1 
ATOM   1041 H HA   . VAL A 1 70  ? 89.79064  -18.93041 7.77374  1.000 62.49763  ? 71  VAL A HA   1 
ATOM   1042 H HB   . VAL A 1 70  ? 91.84710  -20.03072 9.34727  1.000 64.59955  ? 71  VAL A HB   1 
ATOM   1043 H HG11 . VAL A 1 70  ? 91.67132  -18.04379 10.77747 1.000 58.95874  ? 71  VAL A HG11 1 
ATOM   1044 H HG12 . VAL A 1 70  ? 92.52007  -17.85461 9.44806  1.000 58.95874  ? 71  VAL A HG12 1 
ATOM   1045 H HG13 . VAL A 1 70  ? 91.02629  -17.31889 9.51971  1.000 58.95874  ? 71  VAL A HG13 1 
ATOM   1046 H HG21 . VAL A 1 70  ? 90.24447  -20.32329 10.89598 1.000 61.63254  ? 71  VAL A HG21 1 
ATOM   1047 H HG22 . VAL A 1 70  ? 89.44193  -19.03841 10.41796 1.000 61.63254  ? 71  VAL A HG22 1 
ATOM   1048 H HG23 . VAL A 1 70  ? 89.34038  -20.39128 9.59156  1.000 61.63254  ? 71  VAL A HG23 1 
ATOM   1049 N N    . ARG A 1 71  ? 92.80926  -19.03582 6.64740  1.000 45.10146  ? 72  ARG A N    1 
ATOM   1050 C CA   . ARG A 1 71  ? 93.75152  -18.29477 5.82854  1.000 50.54338  ? 72  ARG A CA   1 
ATOM   1051 C C    . ARG A 1 71  ? 93.13158  -17.92229 4.49275  1.000 58.21556  ? 72  ARG A C    1 
ATOM   1052 O O    . ARG A 1 71  ? 93.30639  -16.79030 4.02899  1.000 56.77103  ? 72  ARG A O    1 
ATOM   1053 C CB   . ARG A 1 71  ? 95.01918  -19.10572 5.60854  1.000 50.88515  ? 72  ARG A CB   1 
ATOM   1054 C CG   . ARG A 1 71  ? 96.01681  -18.43652 4.65387  1.000 51.02487  ? 72  ARG A CG   1 
ATOM   1055 C CD   . ARG A 1 71  ? 96.68447  -17.23865 5.33403  1.000 58.82903  ? 72  ARG A CD   1 
ATOM   1056 N NE   . ARG A 1 71  ? 97.49567  -16.43886 4.42501  1.000 53.07253  ? 72  ARG A NE   1 
ATOM   1057 C CZ   . ARG A 1 71  ? 98.82641  -16.41730 4.41228  1.000 49.83768  ? 72  ARG A CZ   1 
ATOM   1058 N NH1  . ARG A 1 71  ? 99.54348  -17.23431 5.16345  1.000 55.43734  ? 72  ARG A NH1  1 
ATOM   1059 N NH2  . ARG A 1 71  ? 99.45638  -15.53586 3.63977  1.000 57.29536  ? 72  ARG A NH2  1 
ATOM   1060 H H    . ARG A 1 71  ? 93.08234  -19.81207 6.89734  1.000 54.19302  ? 72  ARG A H    1 
ATOM   1061 H HA   . ARG A 1 71  ? 93.99496  -17.48116 6.29723  1.000 60.72332  ? 72  ARG A HA   1 
ATOM   1062 H HB2  . ARG A 1 71  ? 95.46270  -19.23032 6.46216  1.000 61.13345  ? 72  ARG A HB2  1 
ATOM   1063 H HB3  . ARG A 1 71  ? 94.77829  -19.96620 5.23112  1.000 61.13345  ? 72  ARG A HB3  1 
ATOM   1064 H HG2  . ARG A 1 71  ? 96.70451  -19.07300 4.40315  1.000 61.30112  ? 72  ARG A HG2  1 
ATOM   1065 H HG3  . ARG A 1 71  ? 95.55057  -18.12317 3.86309  1.000 61.30112  ? 72  ARG A HG3  1 
ATOM   1066 H HD2  . ARG A 1 71  ? 95.99646  -16.66324 5.70340  1.000 70.66610  ? 72  ARG A HD2  1 
ATOM   1067 H HD3  . ARG A 1 71  ? 97.26258  -17.56166 6.04280  1.000 70.66610  ? 72  ARG A HD3  1 
ATOM   1068 H HE   . ARG A 1 71  ? 97.08399  -15.94418 3.85455  1.000 63.75831  ? 72  ARG A HE   1 
ATOM   1069 H HH11 . ARG A 1 71  ? 99.15127  -17.80004 5.67892  1.000 66.59608  ? 72  ARG A HH11 1 
ATOM   1070 H HH12 . ARG A 1 71  ? 100.40240 -17.20033 5.13687  1.000 66.59608  ? 72  ARG A HH12 1 
ATOM   1071 H HH21 . ARG A 1 71  ? 99.00395  -14.98780 3.15549  1.000 68.82570  ? 72  ARG A HH21 1 
ATOM   1072 H HH22 . ARG A 1 71  ? 100.31598 -15.51424 3.62478  1.000 68.82570  ? 72  ARG A HH22 1 
ATOM   1073 N N    . ASP A 1 72  ? 92.43241  -18.87663 3.84694  1.000 57.47476  ? 73  ASP A N    1 
ATOM   1074 C CA   . ASP A 1 72  ? 91.85259  -18.64140 2.53290  1.000 57.97712  ? 73  ASP A CA   1 
ATOM   1075 C C    . ASP A 1 72  ? 90.79256  -17.55555 2.59722  1.000 55.32648  ? 73  ASP A C    1 
ATOM   1076 O O    . ASP A 1 72  ? 90.75641  -16.68467 1.73452  1.000 55.06852  ? 73  ASP A O    1 
ATOM   1077 C CB   . ASP A 1 72  ? 91.27291  -19.93773 1.96047  1.000 64.62466  ? 73  ASP A CB   1 
ATOM   1078 C CG   . ASP A 1 72  ? 92.35559  -20.86547 1.40994  1.000 74.32358  ? 73  ASP A CG   1 
ATOM   1079 O OD1  . ASP A 1 72  ? 93.51659  -20.38972 1.20150  1.000 67.97497  ? 73  ASP A OD1  1 
ATOM   1080 O OD2  . ASP A 1 72  ? 92.04608  -22.07357 1.23612  1.000 69.09580  ? 73  ASP A OD2  1 
ATOM   1081 H H    . ASP A 1 72  ? 92.28502  -19.66539 4.15633  1.000 69.04098  ? 73  ASP A H    1 
ATOM   1082 H HA   . ASP A 1 72  ? 92.55280  -18.34752 1.92938  1.000 69.64381  ? 73  ASP A HA   1 
ATOM   1083 H HB2  . ASP A 1 72  ? 90.79867  -20.41065 2.66215  1.000 77.62086  ? 73  ASP A HB2  1 
ATOM   1084 H HB3  . ASP A 1 72  ? 90.66458  -19.72121 1.23663  1.000 77.62086  ? 73  ASP A HB3  1 
ATOM   1085 N N    . PHE A 1 73  ? 89.95319  -17.56182 3.63003  1.000 55.18492  ? 74  PHE A N    1 
ATOM   1086 C CA   . PHE A 1 73  ? 88.99160  -16.47488 3.80709  1.000 61.62825  ? 74  PHE A CA   1 
ATOM   1087 C C    . PHE A 1 73  ? 89.66816  -15.11250 3.98417  1.000 63.04875  ? 74  PHE A C    1 
ATOM   1088 O O    . PHE A 1 73  ? 89.20904  -14.10574 3.42891  1.000 58.55977  ? 74  PHE A O    1 
ATOM   1089 C CB   . PHE A 1 73  ? 88.12355  -16.75991 5.02475  1.000 55.76180  ? 74  PHE A CB   1 
ATOM   1090 C CG   . PHE A 1 73  ? 87.28684  -15.61770 5.45509  1.000 54.22480  ? 74  PHE A CG   1 
ATOM   1091 C CD1  . PHE A 1 73  ? 86.09649  -15.32643 4.79283  1.000 52.30067  ? 74  PHE A CD1  1 
ATOM   1092 C CD2  . PHE A 1 73  ? 87.67486  -14.82679 6.52087  1.000 49.36346  ? 74  PHE A CD2  1 
ATOM   1093 C CE1  . PHE A 1 73  ? 85.29684  -14.26492 5.19593  1.000 58.52397  ? 74  PHE A CE1  1 
ATOM   1094 C CE2  . PHE A 1 73  ? 86.87855  -13.75196 6.92839  1.000 46.74555  ? 74  PHE A CE2  1 
ATOM   1095 C CZ   . PHE A 1 73  ? 85.68379  -13.47311 6.26286  1.000 51.64557  ? 74  PHE A CZ   1 
ATOM   1096 H H    . PHE A 1 73  ? 89.91907  -18.17315 4.23394  1.000 66.29317  ? 74  PHE A H    1 
ATOM   1097 H HA   . PHE A 1 73  ? 88.44197  -16.43364 3.00890  1.000 74.02516  ? 74  PHE A HA   1 
ATOM   1098 H HB2  . PHE A 1 73  ? 87.52923  -17.49754 4.81599  1.000 66.98543  ? 74  PHE A HB2  1 
ATOM   1099 H HB3  . PHE A 1 73  ? 88.70006  -16.99836 5.76750  1.000 66.98543  ? 74  PHE A HB3  1 
ATOM   1100 H HD1  . PHE A 1 73  ? 85.83357  -15.85012 4.07067  1.000 62.83207  ? 74  PHE A HD1  1 
ATOM   1101 H HD2  . PHE A 1 73  ? 88.46898  -15.01049 6.96868  1.000 59.30742  ? 74  PHE A HD2  1 
ATOM   1102 H HE1  . PHE A 1 73  ? 84.50121  -14.08618 4.74879  1.000 70.30003  ? 74  PHE A HE1  1 
ATOM   1103 H HE2  . PHE A 1 73  ? 87.14559  -13.22183 7.64432  1.000 56.16593  ? 74  PHE A HE2  1 
ATOM   1104 H HZ   . PHE A 1 73  ? 85.15164  -12.76040 6.53445  1.000 62.04595  ? 74  PHE A HZ   1 
ATOM   1105 N N    . LEU A 1 74  ? 90.71920  -15.04396 4.79571  1.000 55.87805  ? 75  LEU A N    1 
ATOM   1106 C CA   . LEU A 1 74  ? 91.35865  -13.75294 5.02491  1.000 62.83458  ? 75  LEU A CA   1 
ATOM   1107 C C    . LEU A 1 74  ? 92.12353  -13.27289 3.79201  1.000 62.11701  ? 75  LEU A C    1 
ATOM   1108 O O    . LEU A 1 74  ? 92.22850  -12.05834 3.57152  1.000 57.23090  ? 75  LEU A O    1 
ATOM   1109 C CB   . LEU A 1 74  ? 92.29421  -13.83573 6.23659  1.000 69.35838  ? 75  LEU A CB   1 
ATOM   1110 C CG   . LEU A 1 74  ? 91.64839  -14.06992 7.60402  1.000 60.20325  ? 75  LEU A CG   1 
ATOM   1111 C CD1  . LEU A 1 74  ? 92.78287  -14.41931 8.60574  1.000 48.53695  ? 75  LEU A CD1  1 
ATOM   1112 C CD2  . LEU A 1 74  ? 90.83185  -12.88374 8.06676  1.000 58.55074  ? 75  LEU A CD2  1 
ATOM   1113 H H    . LEU A 1 74  ? 91.07110  -15.70852 5.21299  1.000 67.12493  ? 75  LEU A H    1 
ATOM   1114 H HA   . LEU A 1 74  ? 90.67184  -13.09699 5.22217  1.000 75.47276  ? 75  LEU A HA   1 
ATOM   1115 H HB2  . LEU A 1 74  ? 92.91119  -14.56907 6.08676  1.000 83.30132  ? 75  LEU A HB2  1 
ATOM   1116 H HB3  . LEU A 1 74  ? 92.78131  -12.99889 6.29433  1.000 83.30132  ? 75  LEU A HB3  1 
ATOM   1117 H HG   . LEU A 1 74  ? 91.01498  -14.80289 7.55455  1.000 72.31517  ? 75  LEU A HG   1 
ATOM   1118 H HD11 . LEU A 1 74  ? 92.38795  -14.66537 9.45685  1.000 58.31560  ? 75  LEU A HD11 1 
ATOM   1119 H HD12 . LEU A 1 74  ? 93.29795  -15.16177 8.25311  1.000 58.31560  ? 75  LEU A HD12 1 
ATOM   1120 H HD13 . LEU A 1 74  ? 93.35469  -13.64390 8.71826  1.000 58.31560  ? 75  LEU A HD13 1 
ATOM   1121 H HD21 . LEU A 1 74  ? 90.48896  -13.06400 8.95605  1.000 70.33216  ? 75  LEU A HD21 1 
ATOM   1122 H HD22 . LEU A 1 74  ? 91.39930  -12.09722 8.08419  1.000 70.33216  ? 75  LEU A HD22 1 
ATOM   1123 H HD23 . LEU A 1 74  ? 90.09586  -12.74702 7.44989  1.000 70.33216  ? 75  LEU A HD23 1 
ATOM   1124 N N    . ASP A 1 75  ? 92.67140  -14.20228 2.99744  1.000 59.25660  ? 76  ASP A N    1 
ATOM   1125 C CA   . ASP A 1 75  ? 93.27639  -13.84860 1.70880  1.000 59.96553  ? 76  ASP A CA   1 
ATOM   1126 C C    . ASP A 1 75  ? 92.23861  -13.29725 0.71897  1.000 58.16704  ? 76  ASP A C    1 
ATOM   1127 O O    . ASP A 1 75  ? 92.50043  -12.32067 -0.00832 1.000 52.26573  ? 76  ASP A O    1 
ATOM   1128 C CB   . ASP A 1 75  ? 93.94999  -15.07970 1.09952  1.000 56.76453  ? 76  ASP A CB   1 
ATOM   1129 C CG   . ASP A 1 75  ? 95.30141  -15.40285 1.72959  1.000 59.89928  ? 76  ASP A CG   1 
ATOM   1130 O OD1  . ASP A 1 75  ? 95.68210  -14.70584 2.70432  1.000 63.81623  ? 76  ASP A OD1  1 
ATOM   1131 O OD2  . ASP A 1 75  ? 95.98248  -16.37154 1.25736  1.000 56.85848  ? 76  ASP A OD2  1 
ATOM   1132 H H    . ASP A 1 75  ? 92.70553  -15.04180 3.18086  1.000 71.17919  ? 76  ASP A H    1 
ATOM   1133 H HA   . ASP A 1 75  ? 93.94205  -13.16110 1.86741  1.000 72.02990  ? 76  ASP A HA   1 
ATOM   1134 H HB2  . ASP A 1 75  ? 93.37177  -15.84833 1.22511  1.000 68.18871  ? 76  ASP A HB2  1 
ATOM   1135 H HB3  . ASP A 1 75  ? 94.09286  -14.92317 0.15295  1.000 68.18871  ? 76  ASP A HB3  1 
ATOM   1136 N N    . THR A 1 76  ? 91.07018  -13.94118 0.65792  1.000 54.94335  ? 77  THR A N    1 
ATOM   1137 C CA   . THR A 1 76  ? 89.97097  -13.46988 -0.17660 1.000 61.51499  ? 77  THR A CA   1 
ATOM   1138 C C    . THR A 1 76  ? 89.51554  -12.07655 0.24221  1.000 64.28165  ? 77  THR A C    1 
ATOM   1139 O O    . THR A 1 76  ? 89.18672  -11.24408 -0.61013 1.000 60.75179  ? 77  THR A O    1 
ATOM   1140 C CB   . THR A 1 76  ? 88.80939  -14.48063 -0.08028 1.000 58.19112  ? 77  THR A CB   1 
ATOM   1141 O OG1  . THR A 1 76  ? 89.24107  -15.77257 -0.55063 1.000 55.83796  ? 77  THR A OG1  1 
ATOM   1142 C CG2  . THR A 1 76  ? 87.58206  -14.02414 -0.84577 1.000 57.09334  ? 77  THR A CG2  1 
ATOM   1143 H H    . THR A 1 76  ? 90.88879  -14.65952 1.09458  1.000 66.00329  ? 77  THR A H    1 
ATOM   1144 H HA   . THR A 1 76  ? 90.26067  -13.41295 -1.10058 1.000 73.88926  ? 77  THR A HA   1 
ATOM   1145 H HB   . THR A 1 76  ? 88.54352  -14.55226 0.84982  1.000 69.90061  ? 77  THR A HB   1 
ATOM   1146 H HG1  . THR A 1 76  ? 89.93825  -16.00764 -0.14532 1.000 67.07682  ? 77  THR A HG1  1 
ATOM   1147 H HG21 . THR A 1 76  ? 86.91096  -14.72451 -0.84481 1.000 68.58327  ? 77  THR A HG21 1 
ATOM   1148 H HG22 . THR A 1 76  ? 87.20908  -13.23020 -0.43169 1.000 68.58327  ? 77  THR A HG22 1 
ATOM   1149 H HG23 . THR A 1 76  ? 87.82079  -13.81817 -1.76309 1.000 68.58327  ? 77  THR A HG23 1 
ATOM   1150 N N    . MET A 1 77  ? 89.47279  -11.81397 1.55123  1.000 64.98518  ? 78  MET A N    1 
ATOM   1151 C CA   . MET A 1 77  ? 89.09951  -10.49216 2.03487  1.000 62.13385  ? 78  MET A CA   1 
ATOM   1152 C C    . MET A 1 77  ? 90.13437  -9.44154  1.65875  1.000 56.60326  ? 78  MET A C    1 
ATOM   1153 O O    . MET A 1 77  ? 89.76557  -8.28995  1.40991  1.000 57.34069  ? 78  MET A O    1 
ATOM   1154 C CB   . MET A 1 77  ? 88.92767  -10.48909 3.54067  1.000 59.35140  ? 78  MET A CB   1 
ATOM   1155 C CG   . MET A 1 77  ? 87.61132  -11.01447 4.06007  1.000 56.70412  ? 78  MET A CG   1 
ATOM   1156 S SD   . MET A 1 77  ? 86.06186  -10.46083 3.44075  1.000 61.91962  ? 78  MET A SD   1 
ATOM   1157 C CE   . MET A 1 77  ? 85.72969  -8.85623  4.11106  1.000 59.62773  ? 78  MET A CE   1 
ATOM   1158 H H    . MET A 1 77  ? 89.65435  -12.38104 2.17177  1.000 78.05349  ? 78  MET A H    1 
ATOM   1159 H HA   . MET A 1 77  ? 88.24576  -10.27645 1.62808  1.000 74.63189  ? 78  MET A HA   1 
ATOM   1160 H HB2  . MET A 1 77  ? 89.62739  -11.03920 3.92625  1.000 71.29295  ? 78  MET A HB2  1 
ATOM   1161 H HB3  . MET A 1 77  ? 89.01419  -9.57493  3.85328  1.000 71.29295  ? 78  MET A HB3  1 
ATOM   1162 H HG2  . MET A 1 77  ? 87.61840  -11.97353 3.91496  1.000 68.11621  ? 78  MET A HG2  1 
ATOM   1163 H HG3  . MET A 1 77  ? 87.59154  -10.82291 5.01076  1.000 68.11621  ? 78  MET A HG3  1 
ATOM   1164 H HE1  . MET A 1 77  ? 84.89859  -8.52374  3.73740  1.000 71.62455  ? 78  MET A HE1  1 
ATOM   1165 H HE2  . MET A 1 77  ? 85.65405  -8.92636  5.07556  1.000 71.62455  ? 78  MET A HE2  1 
ATOM   1166 H HE3  . MET A 1 77  ? 86.45868  -8.25991  3.87893  1.000 71.62455  ? 78  MET A HE3  1 
ATOM   1167 N N    . GLU A 1 78  ? 91.43303  -9.80676  1.63119  1.000 48.44656  ? 79  GLU A N    1 
ATOM   1168 C CA   . GLU A 1 78  ? 92.45496  -8.83038  1.25527  1.000 58.91881  ? 79  GLU A CA   1 
ATOM   1169 C C    . GLU A 1 78  ? 92.37424  -8.51934  -0.24548 1.000 68.94092  ? 79  GLU A C    1 
ATOM   1170 O O    . GLU A 1 78  ? 92.71696  -7.42124  -0.67454 1.000 61.63191  ? 79  GLU A O    1 
ATOM   1171 C CB   . GLU A 1 78  ? 93.84699  -9.32235  1.65995  1.000 54.72217  ? 79  GLU A CB   1 
ATOM   1172 C CG   . GLU A 1 78  ? 94.07468  -9.32574  3.17194  1.000 66.38925  ? 79  GLU A CG   1 
ATOM   1173 C CD   . GLU A 1 78  ? 95.56076  -9.26776  3.61221  1.000 62.37315  ? 79  GLU A CD   1 
ATOM   1174 O OE1  . GLU A 1 78  ? 96.47745  -9.50968  2.78755  1.000 60.32061  ? 79  GLU A OE1  1 
ATOM   1175 O OE2  . GLU A 1 78  ? 95.79157  -8.96163  4.82038  1.000 62.23441  ? 79  GLU A OE2  1 
ATOM   1176 H H    . GLU A 1 78  ? 91.73163  -10.59059 1.82103  1.000 58.20714  ? 79  GLU A H    1 
ATOM   1177 H HA   . GLU A 1 78  ? 92.31040  -8.00302  1.74053  1.000 70.77384  ? 79  GLU A HA   1 
ATOM   1178 H HB2  . GLU A 1 78  ? 93.96355  -10.23042 1.33944  1.000 65.73787  ? 79  GLU A HB2  1 
ATOM   1179 H HB3  . GLU A 1 78  ? 94.51289  -8.74134  1.26006  1.000 65.73787  ? 79  GLU A HB3  1 
ATOM   1180 H HG2  . GLU A 1 78  ? 93.62921  -8.55218  3.55149  1.000 79.73836  ? 79  GLU A HG2  1 
ATOM   1181 H HG3  . GLU A 1 78  ? 93.69515  -10.13991 3.53800  1.000 79.73836  ? 79  GLU A HG3  1 
ATOM   1182 N N    . ALA A 1 79  ? 91.94474  -9.47717  -1.06036 1.000 60.28739  ? 80  ALA A N    1 
ATOM   1183 C CA   . ALA A 1 79  ? 91.68945  -9.24747  -2.46699 1.000 68.04628  ? 80  ALA A CA   1 
ATOM   1184 C C    . ALA A 1 79  ? 90.35821  -8.54833  -2.71565 1.000 64.38345  ? 80  ALA A C    1 
ATOM   1185 O O    . ALA A 1 79  ? 90.05255  -8.24077  -3.86172 1.000 69.07395  ? 80  ALA A O    1 
ATOM   1186 C CB   . ALA A 1 79  ? 91.73050  -10.58892 -3.22067 1.000 60.12012  ? 80  ALA A CB   1 
ATOM   1187 H H    . ALA A 1 79  ? 91.79155  -10.28606 -0.81169 1.000 72.41613  ? 80  ALA A H    1 
ATOM   1188 H HA   . ALA A 1 79  ? 92.38735  -8.68008  -2.83018 1.000 81.72680  ? 80  ALA A HA   1 
ATOM   1189 H HB1  . ALA A 1 79  ? 91.83580  -10.41517 -4.16916 1.000 72.21541  ? 80  ALA A HB1  1 
ATOM   1190 H HB2  . ALA A 1 79  ? 92.48003  -11.11138 -2.89489 1.000 72.21541  ? 80  ALA A HB2  1 
ATOM   1191 H HB3  . ALA A 1 79  ? 90.90093  -11.06589 -3.06186 1.000 72.21541  ? 80  ALA A HB3  1 
ATOM   1192 N N    . ARG A 1 80  ? 89.57685  -8.26088  -1.68340 1.000 64.99927  ? 81  ARG A N    1 
ATOM   1193 C CA   . ARG A 1 80  ? 88.32150  -7.52494  -1.78175 1.000 65.95907  ? 81  ARG A CA   1 
ATOM   1194 C C    . ARG A 1 80  ? 87.22918  -8.30389  -2.51167 1.000 63.80085  ? 81  ARG A C    1 
ATOM   1195 O O    . ARG A 1 80  ? 86.17506  -7.73285  -2.82178 1.000 61.73248  ? 81  ARG A O    1 
ATOM   1196 C CB   . ARG A 1 80  ? 88.49957  -6.15898  -2.45749 1.000 72.41733  ? 81  ARG A CB   1 
ATOM   1197 C CG   . ARG A 1 80  ? 89.47947  -5.16701  -1.75526 1.000 75.55875  ? 81  ARG A CG   1 
ATOM   1198 C CD   . ARG A 1 80  ? 89.44643  -5.31322  -0.22898 1.000 109.08343 ? 81  ARG A CD   1 
ATOM   1199 N NE   . ARG A 1 80  ? 88.26587  -4.72986  0.41749  1.000 101.01502 ? 81  ARG A NE   1 
ATOM   1200 C CZ   . ARG A 1 80  ? 88.04870  -4.73069  1.73251  1.000 96.21860  ? 81  ARG A CZ   1 
ATOM   1201 N NH1  . ARG A 1 80  ? 88.88770  -5.26157  2.59420  1.000 104.24812 ? 81  ARG A NH1  1 
ATOM   1202 N NH2  . ARG A 1 80  ? 86.94974  -4.20734  2.19930  1.000 97.16603  ? 81  ARG A NH2  1 
ATOM   1203 H H    . ARG A 1 80  ? 89.76259  -8.49339  -0.87653 1.000 78.07039  ? 81  ARG A H    1 
ATOM   1204 H HA   . ARG A 1 80  ? 88.01231  -7.36962  -0.87556 1.000 79.22215  ? 81  ARG A HA   1 
ATOM   1205 H HB2  . ARG A 1 80  ? 88.83691  -6.30702  -3.35481 1.000 86.97206  ? 81  ARG A HB2  1 
ATOM   1206 H HB3  . ARG A 1 80  ? 87.63278  -5.72532  -2.49626 1.000 86.97206  ? 81  ARG A HB3  1 
ATOM   1207 H HG2  . ARG A 1 80  ? 90.38417  -5.34397  -2.05710 1.000 90.74177  ? 81  ARG A HG2  1 
ATOM   1208 H HG3  . ARG A 1 80  ? 89.22738  -4.25722  -1.97804 1.000 90.74177  ? 81  ARG A HG3  1 
ATOM   1209 H HD2  . ARG A 1 80  ? 89.46231  -6.25778  -0.00887 1.000 130.97138 ? 81  ARG A HD2  1 
ATOM   1210 H HD3  . ARG A 1 80  ? 90.22811  -4.87333  0.14032  1.000 130.97138 ? 81  ARG A HD3  1 
ATOM   1211 H HE   . ARG A 1 80  ? 87.67363  -4.36234  -0.08628 1.000 121.28929 ? 81  ARG A HE   1 
ATOM   1212 H HH11 . ARG A 1 80  ? 89.61396  -5.62913  2.31664  1.000 125.16901 ? 81  ARG A HH11 1 
ATOM   1213 H HH12 . ARG A 1 80  ? 88.71028  -5.24131  3.43546  1.000 125.16901 ? 81  ARG A HH12 1 
ATOM   1214 H HH21 . ARG A 1 80  ? 86.37322  -3.86595  1.66015  1.000 116.67050 ? 81  ARG A HH21 1 
ATOM   1215 H HH22 . ARG A 1 80  ? 86.80128  -4.20349  3.04638  1.000 116.67050 ? 81  ARG A HH22 1 
ATOM   1216 N N    . ASP A 1 81  ? 87.41063  -9.60665  -2.73977 1.000 60.39347  ? 82  ASP A N    1 
ATOM   1217 C CA   . ASP A 1 81  ? 86.39136  -10.43409 -3.37494 1.000 58.18023  ? 82  ASP A CA   1 
ATOM   1218 C C    . ASP A 1 81  ? 85.33775  -10.91333 -2.37228 1.000 58.94964  ? 82  ASP A C    1 
ATOM   1219 O O    . ASP A 1 81  ? 85.32679  -12.06459 -1.91704 1.000 61.33281  ? 82  ASP A O    1 
ATOM   1220 C CB   . ASP A 1 81  ? 87.06386  -11.61522 -4.06322 1.000 63.87159  ? 82  ASP A CB   1 
ATOM   1221 C CG   . ASP A 1 81  ? 86.10439  -12.39711 -4.96012 1.000 61.73422  ? 82  ASP A CG   1 
ATOM   1222 O OD1  . ASP A 1 81  ? 84.86130  -12.12481 -4.91759 1.000 60.28408  ? 82  ASP A OD1  1 
ATOM   1223 O OD2  . ASP A 1 81  ? 86.60900  -13.28282 -5.70225 1.000 62.93149  ? 82  ASP A OD2  1 
ATOM   1224 H H    . ASP A 1 81  ? 88.12577  -10.03673 -2.53191 1.000 72.54343  ? 82  ASP A H    1 
ATOM   1225 H HA   . ASP A 1 81  ? 85.92009  -9.87872  -4.01554 1.000 69.88755  ? 82  ASP A HA   1 
ATOM   1226 H HB2  . ASP A 1 81  ? 87.79151  -11.28789 -4.61484 1.000 76.71718  ? 82  ASP A HB2  1 
ATOM   1227 H HB3  . ASP A 1 81  ? 87.40621  -12.22201 -3.38831 1.000 76.71718  ? 82  ASP A HB3  1 
ATOM   1228 N N    . LEU A 1 82  ? 84.37211  -10.03707 -2.08748 1.000 57.21287  ? 83  LEU A N    1 
ATOM   1229 C CA   . LEU A 1 82  ? 83.38249  -10.36437 -1.07452 1.000 64.73681  ? 83  LEU A CA   1 
ATOM   1230 C C    . LEU A 1 82  ? 82.47241  -11.51331 -1.49517 1.000 70.53083  ? 83  LEU A C    1 
ATOM   1231 O O    . LEU A 1 82  ? 82.04140  -12.31008 -0.64380 1.000 67.21431  ? 83  LEU A O    1 
ATOM   1232 C CB   . LEU A 1 82  ? 82.52877  -9.14639  -0.74801 1.000 65.61995  ? 83  LEU A CB   1 
ATOM   1233 C CG   . LEU A 1 82  ? 83.22402  -7.95766  -0.08160 1.000 64.04097  ? 83  LEU A CG   1 
ATOM   1234 C CD1  . LEU A 1 82  ? 82.14619  -7.14702  0.66971  1.000 77.00591  ? 83  LEU A CD1  1 
ATOM   1235 C CD2  . LEU A 1 82  ? 84.34743  -8.33238  0.82610  1.000 66.18924  ? 83  LEU A CD2  1 
ATOM   1236 H H    . LEU A 1 82  ? 84.27400  -9.26767  -2.45894 1.000 68.72671  ? 83  LEU A H    1 
ATOM   1237 H HA   . LEU A 1 82  ? 83.86850  -10.63556 -0.28007 1.000 77.75544  ? 83  LEU A HA   1 
ATOM   1238 H HB2  . LEU A 1 82  ? 82.14749  -8.81992  -1.57803 1.000 78.81521  ? 83  LEU A HB2  1 
ATOM   1239 H HB3  . LEU A 1 82  ? 81.82209  -9.43142  -0.14779 1.000 78.81521  ? 83  LEU A HB3  1 
ATOM   1240 H HG   . LEU A 1 82  ? 83.64855  -7.42119  -0.76926 1.000 76.92044  ? 83  LEU A HG   1 
ATOM   1241 H HD11 . LEU A 1 82  ? 82.57191  -6.40838  1.13239  1.000 92.47836  ? 83  LEU A HD11 1 
ATOM   1242 H HD12 . LEU A 1 82  ? 81.50170  -6.80842  0.02870  1.000 92.47836  ? 83  LEU A HD12 1 
ATOM   1243 H HD13 . LEU A 1 82  ? 81.70351  -7.72677  1.30910  1.000 92.47836  ? 83  LEU A HD13 1 
ATOM   1244 H HD21 . LEU A 1 82  ? 84.68951  -7.53115  1.25262  1.000 79.49835  ? 83  LEU A HD21 1 
ATOM   1245 H HD22 . LEU A 1 82  ? 84.01817  -8.94984  1.49784  1.000 79.49835  ? 83  LEU A HD22 1 
ATOM   1246 H HD23 . LEU A 1 82  ? 85.04792  -8.75406  0.30419  1.000 79.49835  ? 83  LEU A HD23 1 
ATOM   1247 N N    . ASP A 1 83  ? 82.10571  -11.57342 -2.77938 1.000 78.69770  ? 84  ASP A N    1 
ATOM   1248 C CA   . ASP A 1 83  ? 81.23578  -12.64457 -3.26219 1.000 76.82830  ? 84  ASP A CA   1 
ATOM   1249 C C    . ASP A 1 83  ? 81.82488  -14.00287 -2.89211 1.000 64.00996  ? 84  ASP A C    1 
ATOM   1250 O O    . ASP A 1 83  ? 81.12563  -14.89063 -2.38965 1.000 62.30742  ? 84  ASP A O    1 
ATOM   1251 C CB   . ASP A 1 83  ? 81.04997  -12.53170 -4.78482 1.000 96.42680  ? 84  ASP A CB   1 
ATOM   1252 C CG   . ASP A 1 83  ? 79.96648  -11.51933 -5.19033 1.000 106.79858 ? 84  ASP A CG   1 
ATOM   1253 O OD1  . ASP A 1 83  ? 79.31436  -10.91307 -4.30557 1.000 91.94264  ? 84  ASP A OD1  1 
ATOM   1254 O OD2  . ASP A 1 83  ? 79.76685  -11.34181 -6.41497 1.000 100.24616 ? 84  ASP A OD2  1 
ATOM   1255 H H    . ASP A 1 83  ? 82.34534  -11.01108 -3.38432 1.000 94.50850  ? 84  ASP A H    1 
ATOM   1256 H HA   . ASP A 1 83  ? 80.36052  -12.55860 -2.85301 1.000 92.26523  ? 84  ASP A HA   1 
ATOM   1257 H HB2  . ASP A 1 83  ? 81.88738  -12.24743 -5.18336 1.000 115.78343 ? 84  ASP A HB2  1 
ATOM   1258 H HB3  . ASP A 1 83  ? 80.79335  -13.39903 -5.13522 1.000 115.78343 ? 84  ASP A HB3  1 
ATOM   1259 N N    . LYS A 1 84  ? 83.12560  -14.18188 -3.13634 1.000 52.38858  ? 85  LYS A N    1 
ATOM   1260 C CA   . LYS A 1 84  ? 83.77344  -15.43315 -2.76011 1.000 55.88501  ? 85  LYS A CA   1 
ATOM   1261 C C    . LYS A 1 84  ? 83.89664  -15.57734 -1.23341 1.000 63.69358  ? 85  LYS A C    1 
ATOM   1262 O O    . LYS A 1 84  ? 83.68021  -16.66599 -0.68580 1.000 61.76532  ? 85  LYS A O    1 
ATOM   1263 C CB   . LYS A 1 84  ? 85.13843  -15.50828 -3.45200 1.000 48.87459  ? 85  LYS A CB   1 
ATOM   1264 C CG   . LYS A 1 84  ? 85.82174  -16.84476 -3.24648 1.000 55.86786  ? 85  LYS A CG   1 
ATOM   1265 C CD   . LYS A 1 84  ? 87.25193  -16.88728 -3.76866 1.000 55.93685  ? 85  LYS A CD   1 
ATOM   1266 C CE   . LYS A 1 84  ? 87.96814  -18.12668 -3.21821 1.000 75.84633  ? 85  LYS A CE   1 
ATOM   1267 N NZ   . LYS A 1 84  ? 89.32367  -18.36989 -3.80703 1.000 71.20182  ? 85  LYS A NZ   1 
ATOM   1268 H H    . LYS A 1 84  ? 83.64245  -13.60546 -3.51080 1.000 62.93757  ? 85  LYS A H    1 
ATOM   1269 H HA   . LYS A 1 84  ? 83.23763  -16.18334 -3.06182 1.000 67.13328  ? 85  LYS A HA   1 
ATOM   1270 H HB2  . LYS A 1 84  ? 85.01772  -15.37516 -4.40521 1.000 58.72078  ? 85  LYS A HB2  1 
ATOM   1271 H HB3  . LYS A 1 84  ? 85.71472  -14.81667 -3.09079 1.000 58.72078  ? 85  LYS A HB3  1 
ATOM   1272 H HG2  . LYS A 1 84  ? 85.84791  -17.04009 -2.29671 1.000 67.11270  ? 85  LYS A HG2  1 
ATOM   1273 H HG3  . LYS A 1 84  ? 85.31655  -17.52944 -3.71219 1.000 67.11270  ? 85  LYS A HG3  1 
ATOM   1274 H HD2  . LYS A 1 84  ? 87.24603  -16.93470 -4.73748 1.000 67.19549  ? 85  LYS A HD2  1 
ATOM   1275 H HD3  . LYS A 1 84  ? 87.73077  -16.09530 -3.47818 1.000 67.19549  ? 85  LYS A HD3  1 
ATOM   1276 H HE2  . LYS A 1 84  ? 88.07968  -18.02056 -2.26051 1.000 91.08686  ? 85  LYS A HE2  1 
ATOM   1277 H HE3  . LYS A 1 84  ? 87.42368  -18.90761 -3.40429 1.000 91.08686  ? 85  LYS A HE3  1 
ATOM   1278 H HZ1  . LYS A 1 84  ? 89.68345  -19.10182 -3.45076 1.000 85.51345  ? 85  LYS A HZ1  1 
ATOM   1279 H HZ2  . LYS A 1 84  ? 89.25772  -18.47979 -4.68776 1.000 85.51345  ? 85  LYS A HZ2  1 
ATOM   1280 H HZ3  . LYS A 1 84  ? 89.85631  -17.67633 -3.64159 1.000 85.51345  ? 85  LYS A HZ3  1 
ATOM   1281 N N    . ALA A 1 85  ? 84.21093  -14.48985 -0.52738 1.000 59.21591  ? 86  ALA A N    1 
ATOM   1282 C CA   . ALA A 1 85  ? 84.33721  -14.56365 0.92183  1.000 60.24084  ? 86  ALA A CA   1 
ATOM   1283 C C    . ALA A 1 85  ? 83.06733  -15.10221 1.56745  1.000 58.76313  ? 86  ALA A C    1 
ATOM   1284 O O    . ALA A 1 85  ? 83.12995  -15.95547 2.46185  1.000 63.89724  ? 86  ALA A O    1 
ATOM   1285 C CB   . ALA A 1 85  ? 84.70855  -13.18257 1.46457  1.000 59.53267  ? 86  ALA A CB   1 
ATOM   1286 H H    . ALA A 1 85  ? 84.35352  -13.71004 -0.86078 1.000 71.13036  ? 86  ALA A H    1 
ATOM   1287 H HA   . ALA A 1 85  ? 85.05071  -15.17714 1.15729  1.000 72.36027  ? 86  ALA A HA   1 
ATOM   1288 H HB1  . ALA A 1 85  ? 84.74326  -13.22274 2.43311  1.000 71.51047  ? 86  ALA A HB1  1 
ATOM   1289 H HB2  . ALA A 1 85  ? 85.57586  -12.92775 1.11279  1.000 71.51047  ? 86  ALA A HB2  1 
ATOM   1290 H HB3  . ALA A 1 85  ? 84.03654  -12.54183 1.18395  1.000 71.51047  ? 86  ALA A HB3  1 
ATOM   1291 N N    . ARG A 1 86  ? 81.90627  -14.64778 1.11367  1.000 58.03722  ? 87  ARG A N    1 
ATOM   1292 C CA   . ARG A 1 86  ? 80.66899  -15.07174 1.75707  1.000 64.67214  ? 87  ARG A CA   1 
ATOM   1293 C C    . ARG A 1 86  ? 80.43785  -16.57552 1.67578  1.000 61.15755  ? 87  ARG A C    1 
ATOM   1294 O O    . ARG A 1 86  ? 79.59121  -17.10534 2.41475  1.000 60.32646  ? 87  ARG A O    1 
ATOM   1295 C CB   . ARG A 1 86  ? 79.46015  -14.37466 1.13747  1.000 64.74197  ? 87  ARG A CB   1 
ATOM   1296 C CG   . ARG A 1 86  ? 79.47136  -12.87628 1.31403  1.000 67.25127  ? 87  ARG A CG   1 
ATOM   1297 C CD   . ARG A 1 86  ? 78.08254  -12.29518 1.10097  1.000 77.88282  ? 87  ARG A CD   1 
ATOM   1298 N NE   . ARG A 1 86  ? 78.03681  -10.87054 1.40722  1.000 99.48967  ? 87  ARG A NE   1 
ATOM   1299 C CZ   . ARG A 1 86  ? 78.59260  -9.92726  0.65744  1.000 86.01731  ? 87  ARG A CZ   1 
ATOM   1300 N NH1  . ARG A 1 86  ? 79.29944  -10.23260 -0.42095 1.000 78.35889  ? 87  ARG A NH1  1 
ATOM   1301 N NH2  . ARG A 1 86  ? 78.44157  -8.64551  1.00395  1.000 79.22231  ? 87  ARG A NH2  1 
ATOM   1302 H H    . ARG A 1 86  ? 81.80866  -14.10711 0.45205  1.000 69.71593  ? 87  ARG A H    1 
ATOM   1303 H HA   . ARG A 1 86  ? 80.73788  -14.81326 2.68946  1.000 77.67784  ? 87  ARG A HA   1 
ATOM   1304 H HB2  . ARG A 1 86  ? 79.44566  -14.56136 0.18571  1.000 77.76163  ? 87  ARG A HB2  1 
ATOM   1305 H HB3  . ARG A 1 86  ? 78.65421  -14.71678 1.55497  1.000 77.76163  ? 87  ARG A HB3  1 
ATOM   1306 H HG2  . ARG A 1 86  ? 79.76106  -12.65855 2.21379  1.000 80.77280  ? 87  ARG A HG2  1 
ATOM   1307 H HG3  . ARG A 1 86  ? 80.07381  -12.47852 0.66615  1.000 80.77280  ? 87  ARG A HG3  1 
ATOM   1308 H HD2  . ARG A 1 86  ? 77.82491  -12.41462 0.17347  1.000 93.53065  ? 87  ARG A HD2  1 
ATOM   1309 H HD3  . ARG A 1 86  ? 77.45294  -12.75072 1.68147  1.000 93.53065  ? 87  ARG A HD3  1 
ATOM   1310 H HE   . ARG A 1 86  ? 77.62275  -10.62559 2.12007  1.000 119.45887 ? 87  ARG A HE   1 
ATOM   1311 H HH11 . ARG A 1 86  ? 79.40528  -11.05561 -0.64690 1.000 94.10193  ? 87  ARG A HH11 1 
ATOM   1312 H HH12 . ARG A 1 86  ? 79.65236  -9.60777  -0.89490 1.000 94.10193  ? 87  ARG A HH12 1 
ATOM   1313 H HH21 . ARG A 1 86  ? 77.98853  -8.44026  1.70554  1.000 95.13803  ? 87  ARG A HH21 1 
ATOM   1314 H HH22 . ARG A 1 86  ? 78.79741  -8.02589  0.52537  1.000 95.13803  ? 87  ARG A HH22 1 
ATOM   1315 N N    . THR A 1 87  ? 81.13328  -17.26733 0.77319  1.000 58.52676  ? 88  THR A N    1 
ATOM   1316 C CA   . THR A 1 87  ? 80.94262  -18.70890 0.65539  1.000 64.73964  ? 88  THR A CA   1 
ATOM   1317 C C    . THR A 1 87  ? 81.60676  -19.49215 1.78512  1.000 67.21846  ? 88  THR A C    1 
ATOM   1318 O O    . THR A 1 87  ? 81.21226  -20.64384 2.05280  1.000 62.86179  ? 88  THR A O    1 
ATOM   1319 C CB   . THR A 1 87  ? 81.48298  -19.19767 -0.67760 1.000 60.86239  ? 88  THR A CB   1 
ATOM   1320 O OG1  . THR A 1 87  ? 82.91039  -19.05080 -0.70317 1.000 60.38869  ? 88  THR A OG1  1 
ATOM   1321 C CG2  . THR A 1 87  ? 80.84962  -18.40215 -1.80717 1.000 61.92388  ? 88  THR A CG2  1 
ATOM   1322 H H    . THR A 1 87  ? 81.70881  -16.93129 0.22965  1.000 70.30338  ? 88  THR A H    1 
ATOM   1323 H HA   . THR A 1 87  ? 79.99096  -18.89420 0.68538  1.000 77.75884  ? 88  THR A HA   1 
ATOM   1324 H HB   . THR A 1 87  ? 81.26877  -20.13496 -0.80601 1.000 73.10614  ? 88  THR A HB   1 
ATOM   1325 H HG1  . THR A 1 87  ? 83.21345  -19.31711 -1.43994 1.000 72.53769  ? 88  THR A HG1  1 
ATOM   1326 H HG21 . THR A 1 87  ? 81.17740  -18.72166 -2.66237 1.000 74.37993  ? 88  THR A HG21 1 
ATOM   1327 H HG22 . THR A 1 87  ? 79.88503  -18.50153 -1.78270 1.000 74.37993  ? 88  THR A HG22 1 
ATOM   1328 H HG23 . THR A 1 87  ? 81.07166  -17.46230 -1.71615 1.000 74.37993  ? 88  THR A HG23 1 
ATOM   1329 N N    . PHE A 1 88  ? 82.58868  -18.88680 2.46016  1.000 64.71323  ? 89  PHE A N    1 
ATOM   1330 C CA   . PHE A 1 88  ? 83.17991  -19.52044 3.62541  1.000 62.04220  ? 89  PHE A CA   1 
ATOM   1331 C C    . PHE A 1 88  ? 82.30007  -19.45287 4.87318  1.000 59.02728  ? 89  PHE A C    1 
ATOM   1332 O O    . PHE A 1 88  ? 82.62816  -20.10344 5.87309  1.000 56.86410  ? 89  PHE A O    1 
ATOM   1333 C CB   . PHE A 1 88  ? 84.51121  -18.86568 3.96825  1.000 55.20762  ? 89  PHE A CB   1 
ATOM   1334 C CG   . PHE A 1 88  ? 85.53437  -18.94246 2.90024  1.000 55.70469  ? 89  PHE A CG   1 
ATOM   1335 C CD1  . PHE A 1 88  ? 85.60343  -17.95840 1.90676  1.000 56.50165  ? 89  PHE A CD1  1 
ATOM   1336 C CD2  . PHE A 1 88  ? 86.48382  -19.96628 2.90673  1.000 51.29571  ? 89  PHE A CD2  1 
ATOM   1337 C CE1  . PHE A 1 88  ? 86.59871  -18.01445 0.93664  1.000 57.91606  ? 89  PHE A CE1  1 
ATOM   1338 C CE2  . PHE A 1 88  ? 87.47520  -20.03020 1.91398  1.000 54.05117  ? 89  PHE A CE2  1 
ATOM   1339 C CZ   . PHE A 1 88  ? 87.52557  -19.06021 0.92807  1.000 55.47119  ? 89  PHE A CZ   1 
ATOM   1340 H H    . PHE A 1 88  ? 82.92084  -18.11907 2.26053  1.000 77.72714  ? 89  PHE A H    1 
ATOM   1341 H HA   . PHE A 1 88  ? 83.32888  -20.45179 3.39890  1.000 74.52191  ? 89  PHE A HA   1 
ATOM   1342 H HB2  . PHE A 1 88  ? 84.35368  -17.92679 4.15422  1.000 66.32041  ? 89  PHE A HB2  1 
ATOM   1343 H HB3  . PHE A 1 88  ? 84.87606  -19.30276 4.75358  1.000 66.32041  ? 89  PHE A HB3  1 
ATOM   1344 H HD1  . PHE A 1 88  ? 84.98271  -17.26595 1.89543  1.000 67.87324  ? 89  PHE A HD1  1 
ATOM   1345 H HD2  . PHE A 1 88  ? 86.45947  -20.61239 3.57520  1.000 61.62612  ? 89  PHE A HD2  1 
ATOM   1346 H HE1  . PHE A 1 88  ? 86.64774  -17.34993 0.28786  1.000 69.57054  ? 89  PHE A HE1  1 
ATOM   1347 H HE2  . PHE A 1 88  ? 88.09617  -20.72249 1.91908  1.000 64.93267  ? 89  PHE A HE2  1 
ATOM   1348 H HZ   . PHE A 1 88  ? 88.17366  -19.10420 0.26253  1.000 66.63670  ? 89  PHE A HZ   1 
ATOM   1349 N N    . LEU A 1 89  ? 81.20792  -18.68899 4.84825  1.000 61.17932  ? 90  LEU A N    1 
ATOM   1350 C CA   . LEU A 1 89  ? 80.53702  -18.27658 6.06448  1.000 58.87953  ? 90  LEU A CA   1 
ATOM   1351 C C    . LEU A 1 89  ? 79.21379  -18.98632 6.28350  1.000 59.26547  ? 90  LEU A C    1 
ATOM   1352 O O    . LEU A 1 89  ? 78.50647  -19.31633 5.33686  1.000 68.61551  ? 90  LEU A O    1 
ATOM   1353 C CB   . LEU A 1 89  ? 80.27326  -16.77022 6.05518  1.000 59.78865  ? 90  LEU A CB   1 
ATOM   1354 C CG   . LEU A 1 89  ? 81.44721  -15.86235 5.67712  1.000 64.33527  ? 90  LEU A CG   1 
ATOM   1355 C CD1  . LEU A 1 89  ? 80.98107  -14.39242 5.67340  1.000 59.86678  ? 90  LEU A CD1  1 
ATOM   1356 C CD2  . LEU A 1 89  ? 82.61599  -16.07415 6.60940  1.000 58.63902  ? 90  LEU A CD2  1 
ATOM   1357 H H    . LEU A 1 89  ? 80.83878  -18.39795 4.12808  1.000 73.48645  ? 90  LEU A H    1 
ATOM   1358 H HA   . LEU A 1 89  ? 81.11691  -18.51617 6.80423  1.000 70.72670  ? 90  LEU A HA   1 
ATOM   1359 H HB2  . LEU A 1 89  ? 79.56337  -16.59526 5.41772  1.000 71.81765  ? 90  LEU A HB2  1 
ATOM   1360 H HB3  . LEU A 1 89  ? 79.99043  -16.51104 6.94610  1.000 71.81765  ? 90  LEU A HB3  1 
ATOM   1361 H HG   . LEU A 1 89  ? 81.75932  -16.08315 4.78564  1.000 77.27359  ? 90  LEU A HG   1 
ATOM   1362 H HD11 . LEU A 1 89  ? 81.75203  -13.81694 5.54955  1.000 71.91140  ? 90  LEU A HD11 1 
ATOM   1363 H HD12 . LEU A 1 89  ? 80.35136  -14.26265 4.94709  1.000 71.91140  ? 90  LEU A HD12 1 
ATOM   1364 H HD13 . LEU A 1 89  ? 80.55343  -14.19458 6.52127  1.000 71.91140  ? 90  LEU A HD13 1 
ATOM   1365 H HD21 . LEU A 1 89  ? 83.19116  -15.29374 6.57712  1.000 70.43809  ? 90  LEU A HD21 1 
ATOM   1366 H HD22 . LEU A 1 89  ? 82.28171  -16.20162 7.51101  1.000 70.43809  ? 90  LEU A HD22 1 
ATOM   1367 H HD23 . LEU A 1 89  ? 83.10843  -16.85997 6.32500  1.000 70.43809  ? 90  LEU A HD23 1 
ATOM   1368 N N    . THR A 1 90  ? 78.88212  -19.19207 7.56117  1.000 59.89368  ? 91  THR A N    1 
ATOM   1369 C CA   . THR A 1 90  ? 77.53661  -19.58039 7.94839  1.000 64.91606  ? 91  THR A CA   1 
ATOM   1370 C C    . THR A 1 90  ? 76.57635  -18.40846 7.74841  1.000 62.77641  ? 91  THR A C    1 
ATOM   1371 O O    . THR A 1 90  ? 76.98394  -17.25546 7.65115  1.000 62.69150  ? 91  THR A O    1 
ATOM   1372 C CB   . THR A 1 90  ? 77.51160  -20.03450 9.40878  1.000 66.97190  ? 91  THR A CB   1 
ATOM   1373 O OG1  . THR A 1 90  ? 77.71465  -18.90555 10.27352 1.000 62.76186  ? 91  THR A OG1  1 
ATOM   1374 C CG2  . THR A 1 90  ? 78.60927  -21.08767 9.67454  1.000 60.75725  ? 91  THR A CG2  1 
ATOM   1375 H H    . THR A 1 90  ? 79.42555  -19.11136 8.22281  1.000 71.94368  ? 91  THR A H    1 
ATOM   1376 H HA   . THR A 1 90  ? 77.23758  -20.32203 7.39935  1.000 77.97054  ? 91  THR A HA   1 
ATOM   1377 H HB   . THR A 1 90  ? 76.65067  -20.43736 9.60221  1.000 80.43754  ? 91  THR A HB   1 
ATOM   1378 H HG1  . THR A 1 90  ? 77.68164  -19.14927 11.07671 1.000 75.38550  ? 91  THR A HG1  1 
ATOM   1379 H HG21 . THR A 1 90  ? 78.49434  -21.47094 10.55817 1.000 72.97996  ? 91  THR A HG21 1 
ATOM   1380 H HG22 . THR A 1 90  ? 78.55570  -21.79651 9.01455  1.000 72.97996  ? 91  THR A HG22 1 
ATOM   1381 H HG23 . THR A 1 90  ? 79.48524  -20.67435 9.62218  1.000 72.97996  ? 91  THR A HG23 1 
ATOM   1382 N N    . ASP A 1 91  ? 75.27948  -18.71490 7.68355  1.000 68.70458  ? 92  ASP A N    1 
ATOM   1383 C CA   . ASP A 1 91  ? 74.31107  -17.66223 7.40370  1.000 69.52312  ? 92  ASP A CA   1 
ATOM   1384 C C    . ASP A 1 91  ? 74.21730  -16.65268 8.52628  1.000 68.27424  ? 92  ASP A C    1 
ATOM   1385 O O    . ASP A 1 91  ? 73.72566  -15.53449 8.30195  1.000 70.78236  ? 92  ASP A O    1 
ATOM   1386 C CB   . ASP A 1 91  ? 72.91438  -18.23160 7.15435  1.000 76.89499  ? 92  ASP A CB   1 
ATOM   1387 C CG   . ASP A 1 91  ? 72.75894  -18.80718 5.75135  1.000 88.26927  ? 92  ASP A CG   1 
ATOM   1388 O OD1  . ASP A 1 91  ? 73.58542  -18.48593 4.85789  1.000 94.42009  ? 92  ASP A OD1  1 
ATOM   1389 O OD2  . ASP A 1 91  ? 71.79948  -19.58503 5.55569  1.000 102.68270 ? 92  ASP A OD2  1 
ATOM   1390 H H    . ASP A 1 91  ? 74.94758  -19.50046 7.79465  1.000 82.51677  ? 92  ASP A H    1 
ATOM   1391 H HA   . ASP A 1 91  ? 74.60325  -17.21818 6.59231  1.000 83.49901  ? 92  ASP A HA   1 
ATOM   1392 H HB2  . ASP A 1 91  ? 72.74371  -18.94263 7.79170  1.000 92.34525  ? 92  ASP A HB2  1 
ATOM   1393 H HB3  . ASP A 1 91  ? 72.25977  -17.52414 7.26338  1.000 92.34525  ? 92  ASP A HB3  1 
ATOM   1394 N N    . ASP A 1 92  ? 74.65470  -17.03367 9.72736  1.000 64.08942  ? 93  ASP A N    1 
ATOM   1395 C CA   . ASP A 1 92  ? 74.57043  -16.17987 10.90629 1.000 67.10264  ? 93  ASP A CA   1 
ATOM   1396 C C    . ASP A 1 92  ? 75.93997  -15.72550 11.40871 1.000 62.04640  ? 93  ASP A C    1 
ATOM   1397 O O    . ASP A 1 92  ? 76.06004  -15.31008 12.57007 1.000 64.00966  ? 93  ASP A O    1 
ATOM   1398 C CB   . ASP A 1 92  ? 73.82846  -16.92101 12.01712 1.000 68.41436  ? 93  ASP A CB   1 
ATOM   1399 C CG   . ASP A 1 92  ? 74.58725  -18.14560 12.47429 1.000 74.15646  ? 93  ASP A CG   1 
ATOM   1400 O OD1  . ASP A 1 92  ? 75.56952  -18.51794 11.78087 1.000 76.05895  ? 93  ASP A OD1  1 
ATOM   1401 O OD2  . ASP A 1 92  ? 74.22715  -18.72237 13.53183 1.000 68.25829  ? 93  ASP A OD2  1 
ATOM   1402 H H    . ASP A 1 92  ? 75.01176  -17.80000 9.88496  1.000 76.97857  ? 93  ASP A H    1 
ATOM   1403 H HA   . ASP A 1 92  ? 74.07286  -15.38105 10.67135 1.000 80.59444  ? 93  ASP A HA   1 
ATOM   1404 H HB2  . ASP A 1 92  ? 73.71762  -16.32973 12.77805 1.000 82.16849  ? 93  ASP A HB2  1 
ATOM   1405 H HB3  . ASP A 1 92  ? 72.96112  -17.20516 11.68867 1.000 82.16849  ? 93  ASP A HB3  1 
ATOM   1406 N N    . PHE A 1 93  ? 76.96262  -15.80839 10.55901 1.000 59.68364  ? 94  PHE A N    1 
ATOM   1407 C CA   . PHE A 1 93  ? 78.29830  -15.32419 10.87695 1.000 63.39683  ? 94  PHE A CA   1 
ATOM   1408 C C    . PHE A 1 93  ? 78.26134  -13.95912 11.53805 1.000 63.73396  ? 94  PHE A C    1 
ATOM   1409 O O    . PHE A 1 93  ? 77.57468  -13.04337 11.07230 1.000 65.47371  ? 94  PHE A O    1 
ATOM   1410 C CB   . PHE A 1 93  ? 79.10233  -15.23515 9.59326  1.000 56.88051  ? 94  PHE A CB   1 
ATOM   1411 C CG   . PHE A 1 93  ? 80.51228  -14.75405 9.76672  1.000 56.48083  ? 94  PHE A CG   1 
ATOM   1412 C CD1  . PHE A 1 93  ? 81.48389  -15.57259 10.34495 1.000 56.59802  ? 94  PHE A CD1  1 
ATOM   1413 C CD2  . PHE A 1 93  ? 80.89415  -13.50592 9.28124  1.000 54.27050  ? 94  PHE A CD2  1 
ATOM   1414 C CE1  . PHE A 1 93  ? 82.82193  -15.14722 10.43690 1.000 58.09435  ? 94  PHE A CE1  1 
ATOM   1415 C CE2  . PHE A 1 93  ? 82.23153  -13.07550 9.36153  1.000 51.29068  ? 94  PHE A CE2  1 
ATOM   1416 C CZ   . PHE A 1 93  ? 83.18466  -13.89860 9.93860  1.000 57.35642  ? 94  PHE A CZ   1 
ATOM   1417 H H    . PHE A 1 93  ? 76.90447  -16.15028 9.77204  1.000 71.69163  ? 94  PHE A H    1 
ATOM   1418 H HA   . PHE A 1 93  ? 78.72155  -15.94315 11.49230 1.000 76.14746  ? 94  PHE A HA   1 
ATOM   1419 H HB2  . PHE A 1 93  ? 79.14249  -16.11791 9.19323  1.000 68.32788  ? 94  PHE A HB2  1 
ATOM   1420 H HB3  . PHE A 1 93  ? 78.65561  -14.61858 8.99227  1.000 68.32788  ? 94  PHE A HB3  1 
ATOM   1421 H HD1  . PHE A 1 93  ? 81.24400  -16.40898 10.67331 1.000 67.98889  ? 94  PHE A HD1  1 
ATOM   1422 H HD2  . PHE A 1 93  ? 80.25578  -12.94852 8.89823  1.000 65.19586  ? 94  PHE A HD2  1 
ATOM   1423 H HE1  . PHE A 1 93  ? 83.46114  -15.69749 10.82869 1.000 69.78449  ? 94  PHE A HE1  1 
ATOM   1424 H HE2  . PHE A 1 93  ? 82.47450  -12.24185 9.02854  1.000 61.62008  ? 94  PHE A HE2  1 
ATOM   1425 H HZ   . PHE A 1 93  ? 84.06916  -13.61651 9.99335  1.000 68.89898  ? 94  PHE A HZ   1 
ATOM   1426 N N    . VAL A 1 94  ? 79.01822  -13.83209 12.62380 1.000 65.14856  ? 95  VAL A N    1 
ATOM   1427 C CA   . VAL A 1 94  ? 79.14458  -12.58896 13.36568 1.000 66.55245  ? 95  VAL A CA   1 
ATOM   1428 C C    . VAL A 1 94  ? 80.62402  -12.28687 13.54352 1.000 60.59243  ? 95  VAL A C    1 
ATOM   1429 O O    . VAL A 1 94  ? 81.40674  -13.16836 13.91952 1.000 62.03752  ? 95  VAL A O    1 
ATOM   1430 C CB   . VAL A 1 94  ? 78.44456  -12.65959 14.73303 1.000 68.50337  ? 95  VAL A CB   1 
ATOM   1431 C CG1  . VAL A 1 94  ? 78.47586  -11.28770 15.35618 1.000 75.65926  ? 95  VAL A CG1  1 
ATOM   1432 C CG2  . VAL A 1 94  ? 77.03575  -13.14990 14.57142 1.000 78.23160  ? 95  VAL A CG2  1 
ATOM   1433 H H    . VAL A 1 94  ? 79.48167  -14.47479 12.95807 1.000 78.24954  ? 95  VAL A H    1 
ATOM   1434 H HA   . VAL A 1 94  ? 78.74117  -11.87072 12.85353 1.000 79.93420  ? 95  VAL A HA   1 
ATOM   1435 H HB   . VAL A 1 94  ? 78.90086  -13.28449 15.31799 1.000 82.27531  ? 95  VAL A HB   1 
ATOM   1436 H HG11 . VAL A 1 94  ? 78.01465  -11.31762 16.20899 1.000 90.86238  ? 95  VAL A HG11 1 
ATOM   1437 H HG12 . VAL A 1 94  ? 79.39931  -11.02203 15.48868 1.000 90.86238  ? 95  VAL A HG12 1 
ATOM   1438 H HG13 . VAL A 1 94  ? 78.03330  -10.66105 14.76259 1.000 90.86238  ? 95  VAL A HG13 1 
ATOM   1439 H HG21 . VAL A 1 94  ? 76.60199  -13.15594 15.43901 1.000 93.94918  ? 95  VAL A HG21 1 
ATOM   1440 H HG22 . VAL A 1 94  ? 76.56176  -12.55574 13.96875 1.000 93.94918  ? 95  VAL A HG22 1 
ATOM   1441 H HG23 . VAL A 1 94  ? 77.05395  -14.04762 14.20444 1.000 93.94918  ? 95  VAL A HG23 1 
ATOM   1442 N N    . MET A 1 95  ? 81.00237  -11.04308 13.29146 1.000 61.07908  ? 96  MET A N    1 
ATOM   1443 C CA   . MET A 1 95  ? 82.35307  -10.55175 13.53243 1.000 61.61486  ? 96  MET A CA   1 
ATOM   1444 C C    . MET A 1 95  ? 82.27176  -9.47922  14.61539 1.000 61.40591  ? 96  MET A C    1 
ATOM   1445 O O    . MET A 1 95  ? 81.27254  -8.75181  14.72458 1.000 57.72447  ? 96  MET A O    1 
ATOM   1446 C CB   . MET A 1 95  ? 83.01996  -10.05459 12.18503 1.000 64.48198  ? 96  MET A CB   1 
ATOM   1447 C CG   . MET A 1 95  ? 82.30933  -8.94055  11.44847 1.000 72.39904  ? 96  MET A CG   1 
ATOM   1448 S SD   . MET A 1 95  ? 82.28204  -9.08096  9.62481  1.000 64.08495  ? 96  MET A SD   1 
ATOM   1449 C CE   . MET A 1 95  ? 83.96845  -9.51815  9.32449  1.000 54.13357  ? 96  MET A CE   1 
ATOM   1450 H H    . MET A 1 95  ? 80.47722  -10.44308 12.96924 1.000 73.36616  ? 96  MET A H    1 
ATOM   1451 H HA   . MET A 1 95  ? 82.94446  -11.24858 13.85737 1.000 74.00910  ? 96  MET A HA   1 
ATOM   1452 H HB2  . MET A 1 95  ? 83.91218  -9.73470  12.39124 1.000 77.44964  ? 96  MET A HB2  1 
ATOM   1453 H HB3  . MET A 1 95  ? 83.07024  -10.80947 11.57796 1.000 77.44964  ? 96  MET A HB3  1 
ATOM   1454 H HG2  . MET A 1 95  ? 81.38707  -8.91774  11.74814 1.000 86.95012  ? 96  MET A HG2  1 
ATOM   1455 H HG3  . MET A 1 95  ? 82.74935  -8.10368  11.66507 1.000 86.95012  ? 96  MET A HG3  1 
ATOM   1456 H HE1  . MET A 1 95  ? 84.10111  -9.62763  8.36986  1.000 65.03155  ? 96  MET A HE1  1 
ATOM   1457 H HE2  . MET A 1 95  ? 84.54234  -8.81142  9.65929  1.000 65.03155  ? 96  MET A HE2  1 
ATOM   1458 H HE3  . MET A 1 95  ? 84.16565  -10.34968 9.78336  1.000 65.03155  ? 96  MET A HE3  1 
ATOM   1459 N N    . THR A 1 96  ? 83.29634  -9.44356  15.46535 1.000 61.66160  ? 97  THR A N    1 
ATOM   1460 C CA   . THR A 1 96  ? 83.46868  -8.39200  16.44723 1.000 57.25950  ? 97  THR A CA   1 
ATOM   1461 C C    . THR A 1 96  ? 84.86222  -7.78841  16.30816 1.000 50.52064  ? 97  THR A C    1 
ATOM   1462 O O    . THR A 1 96  ? 85.87177  -8.50879  16.39071 1.000 49.90237  ? 97  THR A O    1 
ATOM   1463 C CB   . THR A 1 96  ? 83.29106  -8.89549  17.89751 1.000 57.91453  ? 97  THR A CB   1 
ATOM   1464 O OG1  . THR A 1 96  ? 81.94750  -9.34858  18.12167 1.000 52.06930  ? 97  THR A OG1  1 
ATOM   1465 C CG2  . THR A 1 96  ? 83.62134  -7.74391  18.86427 1.000 50.05551  ? 97  THR A CG2  1 
ATOM   1466 H H    . THR A 1 96  ? 83.91850  -10.03685 15.48807 1.000 74.06518  ? 97  THR A H    1 
ATOM   1467 H HA   . THR A 1 96  ? 82.79871  -7.71268  16.27238 1.000 68.78266  ? 97  THR A HA   1 
ATOM   1468 H HB   . THR A 1 96  ? 83.88536  -9.64394  18.06344 1.000 69.56870  ? 97  THR A HB   1 
ATOM   1469 H HG1  . THR A 1 96  ? 81.43780  -9.04046  17.52932 1.000 62.55443  ? 97  THR A HG1  1 
ATOM   1470 H HG21 . THR A 1 96  ? 83.17918  -7.88821  19.71549 1.000 60.13788  ? 97  THR A HG21 1 
ATOM   1471 H HG22 . THR A 1 96  ? 84.57911  -7.69814  19.01081 1.000 60.13788  ? 97  THR A HG22 1 
ATOM   1472 H HG23 . THR A 1 96  ? 83.31926  -6.90087  18.49154 1.000 60.13788  ? 97  THR A HG23 1 
ATOM   1473 N N    . PHE A 1 97  ? 84.92689  -6.45743  16.09567 1.000 50.81504  ? 98  PHE A N    1 
ATOM   1474 C CA   . PHE A 1 97  ? 86.22110  -5.78301  15.89151 1.000 51.02459  ? 98  PHE A CA   1 
ATOM   1475 C C    . PHE A 1 97  ? 86.54548  -4.85621  17.06860 1.000 49.85448  ? 98  PHE A C    1 
ATOM   1476 O O    . PHE A 1 97  ? 85.69345  -4.62643  17.93503 1.000 46.34822  ? 98  PHE A O    1 
ATOM   1477 C CB   . PHE A 1 97  ? 86.19527  -5.04581  14.53546 1.000 54.16609  ? 98  PHE A CB   1 
ATOM   1478 C CG   . PHE A 1 97  ? 86.58080  -5.94422  13.33639 1.000 49.30341  ? 98  PHE A CG   1 
ATOM   1479 C CD1  . PHE A 1 97  ? 85.72218  -6.94217  12.86674 1.000 51.59970  ? 98  PHE A CD1  1 
ATOM   1480 C CD2  . PHE A 1 97  ? 87.80343  -5.76351  12.69427 1.000 46.28785  ? 98  PHE A CD2  1 
ATOM   1481 C CE1  . PHE A 1 97  ? 86.09812  -7.76185  11.81664 1.000 52.46268  ? 98  PHE A CE1  1 
ATOM   1482 C CE2  . PHE A 1 97  ? 88.19242  -6.59359  11.61677 1.000 47.22167  ? 98  PHE A CE2  1 
ATOM   1483 C CZ   . PHE A 1 97  ? 87.33731  -7.58767  11.18707 1.000 51.03960  ? 98  PHE A CZ   1 
ATOM   1484 H H    . PHE A 1 97  ? 84.24485  -5.93439  16.06627 1.000 61.04932  ? 98  PHE A H    1 
ATOM   1485 H HA   . PHE A 1 97  ? 86.94442  -6.42883  15.86671 1.000 61.30077  ? 98  PHE A HA   1 
ATOM   1486 H HB2  . PHE A 1 97  ? 85.29873  -4.71023  14.37896 1.000 65.07057  ? 98  PHE A HB2  1 
ATOM   1487 H HB3  . PHE A 1 97  ? 86.82451  -4.30832  14.56840 1.000 65.07057  ? 98  PHE A HB3  1 
ATOM   1488 H HD1  . PHE A 1 97  ? 84.88920  -7.05669  13.26414 1.000 61.99091  ? 98  PHE A HD1  1 
ATOM   1489 H HD2  . PHE A 1 97  ? 88.37353  -5.08596  12.97854 1.000 55.61669  ? 98  PHE A HD2  1 
ATOM   1490 H HE1  . PHE A 1 97  ? 85.52364  -8.43335  11.52686 1.000 63.02648  ? 98  PHE A HE1  1 
ATOM   1491 H HE2  . PHE A 1 97  ? 89.01586  -6.47058  11.20238 1.000 56.73726  ? 98  PHE A HE2  1 
ATOM   1492 H HZ   . PHE A 1 97  ? 87.58314  -8.14081  10.48102 1.000 61.31878  ? 98  PHE A HZ   1 
ATOM   1493 N N    . PRO A 1 98  ? 87.75730  -4.30035  17.11538 1.000 47.89342  ? 99  PRO A N    1 
ATOM   1494 C CA   . PRO A 1 98  ? 88.10375  -3.38555  18.20490 1.000 48.12287  ? 99  PRO A CA   1 
ATOM   1495 C C    . PRO A 1 98  ? 87.06937  -2.28271  18.38330 1.000 54.34827  ? 99  PRO A C    1 
ATOM   1496 O O    . PRO A 1 98  ? 86.50126  -1.77077  17.41416 1.000 50.67365  ? 99  PRO A O    1 
ATOM   1497 C CB   . PRO A 1 98  ? 89.47478  -2.83079  17.78952 1.000 50.79773  ? 99  PRO A CB   1 
ATOM   1498 C CG   . PRO A 1 98  ? 90.10193  -3.90603  16.99532 1.000 48.55871  ? 99  PRO A CG   1 
ATOM   1499 C CD   . PRO A 1 98  ? 88.92726  -4.62613  16.27123 1.000 47.06133  ? 99  PRO A CD   1 
ATOM   1500 H HA   . PRO A 1 98  ? 88.18904  -3.87367  19.03879 1.000 57.81872  ? 99  PRO A HA   1 
ATOM   1501 H HB2  . PRO A 1 98  ? 89.35797  -2.02907  17.25614 1.000 61.02855  ? 99  PRO A HB2  1 
ATOM   1502 H HB3  . PRO A 1 98  ? 90.00196  -2.63034  18.57870 1.000 61.02855  ? 99  PRO A HB3  1 
ATOM   1503 H HG2  . PRO A 1 98  ? 90.71989  -3.52283  16.35329 1.000 58.34172  ? 99  PRO A HG2  1 
ATOM   1504 H HG3  . PRO A 1 98  ? 90.57163  -4.51792  17.58343 1.000 58.34172  ? 99  PRO A HG3  1 
ATOM   1505 H HD2  . PRO A 1 98  ? 88.81163  -4.28015  15.37244 1.000 56.54486  ? 99  PRO A HD2  1 
ATOM   1506 H HD3  . PRO A 1 98  ? 89.07546  -5.58428  16.24138 1.000 56.54486  ? 99  PRO A HD3  1 
ATOM   1507 N N    . THR A 1 99  ? 86.86648  -1.91450  19.65640 1.000 52.81921  ? 100 THR A N    1 
ATOM   1508 C CA   . THR A 1 99  ? 85.78277  -1.10074  20.25503 1.000 55.65255  ? 100 THR A CA   1 
ATOM   1509 C C    . THR A 1 99  ? 84.56113  -1.98578  20.54023 1.000 56.55524  ? 100 THR A C    1 
ATOM   1510 O O    . THR A 1 99  ? 83.54119  -1.49146  21.01446 1.000 55.16433  ? 100 THR A O    1 
ATOM   1511 C CB   . THR A 1 99  ? 85.30205  0.07746   19.38397 1.000 55.07003  ? 100 THR A CB   1 
ATOM   1512 O OG1  . THR A 1 99  ? 84.55202  -0.44142  18.27255 1.000 60.43370  ? 100 THR A OG1  1 
ATOM   1513 C CG2  . THR A 1 99  ? 86.48826  0.92028   18.87645 1.000 55.97411  ? 100 THR A CG2  1 
ATOM   1514 H H    . THR A 1 99  ? 87.41437  -2.15478  20.27421 1.000 63.45432  ? 100 THR A H    1 
ATOM   1515 H HA   . THR A 1 99  ? 86.12652  -0.71449  21.07573 1.000 66.85433  ? 100 THR A HA   1 
ATOM   1516 H HB   . THR A 1 99  ? 84.73995  0.66620   19.91154 1.000 66.15530  ? 100 THR A HB   1 
ATOM   1517 H HG1  . THR A 1 99  ? 85.05440  -0.89174  17.77212 1.000 72.59170  ? 100 THR A HG1  1 
ATOM   1518 H HG21 . THR A 1 99  ? 86.16189  1.71361   18.42367 1.000 67.24020  ? 100 THR A HG21 1 
ATOM   1519 H HG22 . THR A 1 99  ? 87.04630  1.19067   19.62237 1.000 67.24020  ? 100 THR A HG22 1 
ATOM   1520 H HG23 . THR A 1 99  ? 87.02268  0.40087   18.25556 1.000 67.24020  ? 100 THR A HG23 1 
ATOM   1521 N N    . GLY A 1 100 ? 84.58720  -3.25528  20.15280 1.000 57.64701  ? 101 GLY A N    1 
ATOM   1522 C CA   . GLY A 1 100 ? 83.41794  -4.08550  20.32615 1.000 57.02550  ? 101 GLY A CA   1 
ATOM   1523 C C    . GLY A 1 100 ? 82.38412  -3.93808  19.25001 1.000 60.01260  ? 101 GLY A C    1 
ATOM   1524 O O    . GLY A 1 100 ? 81.23049  -4.33191  19.46560 1.000 59.98523  ? 101 GLY A O    1 
ATOM   1525 H H    . GLY A 1 100 ? 85.26216  -3.64839  19.79294 1.000 69.24768  ? 101 GLY A H    1 
ATOM   1526 H HA2  . GLY A 1 100 ? 83.69548  -5.01473  20.34627 1.000 68.50186  ? 101 GLY A HA2  1 
ATOM   1527 H HA3  . GLY A 1 100 ? 82.99978  -3.86241  21.17247 1.000 68.50186  ? 101 GLY A HA3  1 
ATOM   1528 N N    . ARG A 1 101 ? 82.75394  -3.38865  18.09567 1.000 62.46836  ? 102 ARG A N    1 
ATOM   1529 C CA   . ARG A 1 101 ? 81.80208  -3.23489  17.00785 1.000 74.66441  ? 102 ARG A CA   1 
ATOM   1530 C C    . ARG A 1 101 ? 81.38891  -4.61693  16.49822 1.000 65.68786  ? 102 ARG A C    1 
ATOM   1531 O O    . ARG A 1 101 ? 82.24908  -5.42539  16.10308 1.000 49.15120  ? 102 ARG A O    1 
ATOM   1532 C CB   . ARG A 1 101 ? 82.41978  -2.40793  15.88851 1.000 81.58097  ? 102 ARG A CB   1 
ATOM   1533 C CG   . ARG A 1 101 ? 81.52885  -2.28580  14.70309 1.000 85.10017  ? 102 ARG A CG   1 
ATOM   1534 C CD   . ARG A 1 101 ? 82.06482  -1.25472  13.74043 1.000 87.04176  ? 102 ARG A CD   1 
ATOM   1535 N NE   . ARG A 1 101 ? 81.14929  -1.10668  12.62327 1.000 93.50372  ? 102 ARG A NE   1 
ATOM   1536 C CZ   . ARG A 1 101 ? 80.07794  -0.32646  12.62734 1.000 81.88746  ? 102 ARG A CZ   1 
ATOM   1537 N NH1  . ARG A 1 101 ? 79.79943  0.45270   13.64371 1.000 90.87203  ? 102 ARG A NH1  1 
ATOM   1538 N NH2  . ARG A 1 101 ? 79.25329  -0.34386  11.58748 1.000 85.16235  ? 102 ARG A NH2  1 
ATOM   1539 H H    . ARG A 1 101 ? 83.54511  -3.09994  17.92159 1.000 75.03330  ? 102 ARG A H    1 
ATOM   1540 H HA   . ARG A 1 101 ? 81.01089  -2.77101  17.32367 1.000 89.66856  ? 102 ARG A HA   1 
ATOM   1541 H HB2  . ARG A 1 101 ? 82.60259  -1.51484  16.21999 1.000 97.96843  ? 102 ARG A HB2  1 
ATOM   1542 H HB3  . ARG A 1 101 ? 83.24444  -2.83073  15.60202 1.000 97.96843  ? 102 ARG A HB3  1 
ATOM   1543 H HG2  . ARG A 1 101 ? 81.47899  -3.13935  14.24499 1.000 102.19147 ? 102 ARG A HG2  1 
ATOM   1544 H HG3  . ARG A 1 101 ? 80.64376  -2.01053  14.98901 1.000 102.19147 ? 102 ARG A HG3  1 
ATOM   1545 H HD2  . ARG A 1 101 ? 82.15056  -0.39946  14.18997 1.000 104.52138 ? 102 ARG A HD2  1 
ATOM   1546 H HD3  . ARG A 1 101 ? 82.92801  -1.53951  13.40175 1.000 104.52138 ? 102 ARG A HD3  1 
ATOM   1547 H HE   . ARG A 1 101 ? 81.31368  -1.55667  11.90907 1.000 112.27573 ? 102 ARG A HE   1 
ATOM   1548 H HH11 . ARG A 1 101 ? 80.31758  0.46602   14.32996 1.000 109.11771 ? 102 ARG A HH11 1 
ATOM   1549 H HH12 . ARG A 1 101 ? 79.09853  0.95066   13.62439 1.000 109.11771 ? 102 ARG A HH12 1 
ATOM   1550 H HH21 . ARG A 1 101 ? 79.41613  -0.85867  10.91811 1.000 102.26608 ? 102 ARG A HH21 1 
ATOM   1551 H HH22 . ARG A 1 101 ? 78.55613  0.15967   11.58307 1.000 102.26608 ? 102 ARG A HH22 1 
ATOM   1552 N N    . ARG A 1 102 ? 80.08090  -4.88721  16.50252 1.000 58.53272  ? 103 ARG A N    1 
ATOM   1553 C CA   . ARG A 1 102 ? 79.54214  -6.17737  16.09645 1.000 67.50894  ? 103 ARG A CA   1 
ATOM   1554 C C    . ARG A 1 102 ? 78.81609  -6.02448  14.76572 1.000 69.07858  ? 103 ARG A C    1 
ATOM   1555 O O    . ARG A 1 102 ? 77.91967  -5.18222  14.63996 1.000 69.78559  ? 103 ARG A O    1 
ATOM   1556 C CB   . ARG A 1 102 ? 78.61391  -6.72159  17.18521 1.000 75.87969  ? 103 ARG A CB   1 
ATOM   1557 C CG   . ARG A 1 102 ? 77.83929  -7.95495  16.79427 1.000 87.03758  ? 103 ARG A CG   1 
ATOM   1558 C CD   . ARG A 1 102 ? 76.66750  -8.23471  17.74890 1.000 98.36887  ? 103 ARG A CD   1 
ATOM   1559 N NE   . ARG A 1 102 ? 76.46641  -9.66630  17.93050 1.000 105.41621 ? 103 ARG A NE   1 
ATOM   1560 C CZ   . ARG A 1 102 ? 77.28365  -10.44888 18.62718 1.000 93.05118  ? 103 ARG A CZ   1 
ATOM   1561 N NH1  . ARG A 1 102 ? 78.36749  -9.96760  19.21377 1.000 83.51658  ? 103 ARG A NH1  1 
ATOM   1562 N NH2  . ARG A 1 102 ? 77.01738  -11.75079 18.72777 1.000 95.79985  ? 103 ARG A NH2  1 
ATOM   1563 H H    . ARG A 1 102 ? 79.47731  -4.32363  16.74263 1.000 70.31053  ? 103 ARG A H    1 
ATOM   1564 H HA   . ARG A 1 102 ? 80.25579  -6.82006  15.96030 1.000 81.08200  ? 103 ARG A HA   1 
ATOM   1565 H HB2  . ARG A 1 102 ? 79.14917  -6.94687  17.96215 1.000 91.12689  ? 103 ARG A HB2  1 
ATOM   1566 H HB3  . ARG A 1 102 ? 77.97039  -6.03282  17.41407 1.000 91.12689  ? 103 ARG A HB3  1 
ATOM   1567 H HG2  . ARG A 1 102 ? 77.47895  -7.83485  15.90173 1.000 104.51637 ? 103 ARG A HG2  1 
ATOM   1568 H HG3  . ARG A 1 102 ? 78.43245  -8.72225  16.81210 1.000 104.51637 ? 103 ARG A HG3  1 
ATOM   1569 H HD2  . ARG A 1 102 ? 76.85561  -7.83951  18.61454 1.000 118.11391 ? 103 ARG A HD2  1 
ATOM   1570 H HD3  . ARG A 1 102 ? 75.85422  -7.85537  17.38069 1.000 118.11391 ? 103 ARG A HD3  1 
ATOM   1571 H HE   . ARG A 1 102 ? 75.77673  -10.02680 17.56447 1.000 126.57072 ? 103 ARG A HE   1 
ATOM   1572 H HH11 . ARG A 1 102 ? 78.55614  -9.13107  19.14870 1.000 100.29116 ? 103 ARG A HH11 1 
ATOM   1573 H HH12 . ARG A 1 102 ? 78.88335  -10.49128 19.66013 1.000 100.29116 ? 103 ARG A HH12 1 
ATOM   1574 H HH21 . ARG A 1 102 ? 76.32120  -12.07826 18.34346 1.000 115.03109 ? 103 ARG A HH21 1 
ATOM   1575 H HH22 . ARG A 1 102 ? 77.54174  -12.26348 19.17700 1.000 115.03109 ? 103 ARG A HH22 1 
ATOM   1576 N N    . MET A 1 103 ? 79.19120  -6.85951  13.78378 1.000 71.09544  ? 104 MET A N    1 
ATOM   1577 C CA   . MET A 1 103 ? 78.71857  -6.73833  12.40683 1.000 71.68141  ? 104 MET A CA   1 
ATOM   1578 C C    . MET A 1 103 ? 78.36903  -8.11034  11.87160 1.000 70.94586  ? 104 MET A C    1 
ATOM   1579 O O    . MET A 1 103 ? 79.02463  -9.09694  12.21021 1.000 68.03697  ? 104 MET A O    1 
ATOM   1580 C CB   . MET A 1 103 ? 79.78464  -6.11823  11.48887 1.000 59.09588  ? 104 MET A CB   1 
ATOM   1581 C CG   . MET A 1 103 ? 80.32769  -4.87002  12.09574 1.000 70.66165  ? 104 MET A CG   1 
ATOM   1582 S SD   . MET A 1 103 ? 81.51279  -3.99009  11.14541 1.000 61.16011  ? 104 MET A SD   1 
ATOM   1583 C CE   . MET A 1 103 ? 83.12313  -4.54572  11.71220 1.000 63.28826  ? 104 MET A CE   1 
ATOM   1584 H H    . MET A 1 103 ? 79.73198  -7.51821  13.89900 1.000 85.38579  ? 104 MET A H    1 
ATOM   1585 H HA   . MET A 1 103 ? 77.93178  -6.17102  12.40216 1.000 86.08896  ? 104 MET A HA   1 
ATOM   1586 H HB2  . MET A 1 103 ? 80.51337  -6.74660  11.36642 1.000 70.98633  ? 104 MET A HB2  1 
ATOM   1587 H HB3  . MET A 1 103 ? 79.38761  -5.89942  10.63132 1.000 70.98633  ? 104 MET A HB3  1 
ATOM   1588 H HG2  . MET A 1 103 ? 79.58647  -4.26526  12.25623 1.000 84.86524  ? 104 MET A HG2  1 
ATOM   1589 H HG3  . MET A 1 103 ? 80.75340  -5.10323  12.93555 1.000 84.86524  ? 104 MET A HG3  1 
ATOM   1590 H HE1  . MET A 1 103 ? 83.81174  -4.08383  11.20884 1.000 76.01718  ? 104 MET A HE1  1 
ATOM   1591 H HE2  . MET A 1 103 ? 83.21235  -4.34399  12.65679 1.000 76.01718  ? 104 MET A HE2  1 
ATOM   1592 H HE3  . MET A 1 103 ? 83.19509  -5.50255  11.57008 1.000 76.01718  ? 104 MET A HE3  1 
ATOM   1593 N N    . THR A 1 104 ? 77.35342  -8.16003  11.00949 1.000 73.10886  ? 105 THR A N    1 
ATOM   1594 C CA   . THR A 1 104 ? 76.98073  -9.40616  10.36277 1.000 75.50776  ? 105 THR A CA   1 
ATOM   1595 C C    . THR A 1 104 ? 77.10102  -9.37175  8.86006  1.000 69.77766  ? 105 THR A C    1 
ATOM   1596 O O    . THR A 1 104 ? 76.82211  -10.38624 8.22146  1.000 63.01247  ? 105 THR A O    1 
ATOM   1597 C CB   . THR A 1 104 ? 75.53984  -9.79793  10.68290 1.000 68.14616  ? 105 THR A CB   1 
ATOM   1598 O OG1  . THR A 1 104 ? 74.66805  -8.71833  10.35842 1.000 68.60949  ? 105 THR A OG1  1 
ATOM   1599 C CG2  . THR A 1 104 ? 75.44463  -10.09737 12.12078 1.000 69.36250  ? 105 THR A CG2  1 
ATOM   1600 H H    . THR A 1 104 ? 76.86973  -7.48464  10.78699 1.000 87.80190  ? 105 THR A H    1 
ATOM   1601 H HA   . THR A 1 104 ? 77.57616  -10.08417 10.71869 1.000 90.68058  ? 105 THR A HA   1 
ATOM   1602 H HB   . THR A 1 104 ? 75.27111  -10.57689 10.17115 1.000 81.84666  ? 105 THR A HB   1 
ATOM   1603 H HG1  . THR A 1 104 ? 74.71738  -8.12205  10.94801 1.000 82.40265  ? 105 THR A HG1  1 
ATOM   1604 H HG21 . THR A 1 104 ? 74.54077  -10.36976 12.34380 1.000 83.30627  ? 105 THR A HG21 1 
ATOM   1605 H HG22 . THR A 1 104 ? 76.05554  -10.81464 12.35145 1.000 83.30627  ? 105 THR A HG22 1 
ATOM   1606 H HG23 . THR A 1 104 ? 75.67320  -9.31018  12.63944 1.000 83.30627  ? 105 THR A HG23 1 
ATOM   1607 N N    . ASP A 1 105 ? 77.48679  -8.23844  8.28869  1.000 80.20767  ? 106 ASP A N    1 
ATOM   1608 C CA   . ASP A 1 105 ? 77.50777  -8.02009  6.85180  1.000 77.95166  ? 106 ASP A CA   1 
ATOM   1609 C C    . ASP A 1 105 ? 78.92201  -7.59168  6.48158  1.000 69.88627  ? 106 ASP A C    1 
ATOM   1610 O O    . ASP A 1 105 ? 79.45358  -6.63319  7.04573  1.000 69.32579  ? 106 ASP A O    1 
ATOM   1611 C CB   . ASP A 1 105 ? 76.43216  -6.99345  6.44707  1.000 79.40987  ? 106 ASP A CB   1 
ATOM   1612 C CG   . ASP A 1 105 ? 76.43550  -6.74167  4.95354  1.000 105.02833 ? 106 ASP A CG   1 
ATOM   1613 O OD1  . ASP A 1 105 ? 77.35790  -7.21764  4.20993  1.000 92.07175  ? 106 ASP A OD1  1 
ATOM   1614 O OD2  . ASP A 1 105 ? 75.49710  -6.08231  4.48179  1.000 112.59704 ? 106 ASP A OD2  1 
ATOM   1615 H H    . ASP A 1 105 ? 77.75229  -7.55187  8.73337  1.000 96.32047  ? 106 ASP A H    1 
ATOM   1616 H HA   . ASP A 1 105 ? 77.31384  -8.83214  6.35798  1.000 93.61325  ? 106 ASP A HA   1 
ATOM   1617 H HB2  . ASP A 1 105 ? 75.55754  -7.32995  6.69749  1.000 95.36311  ? 106 ASP A HB2  1 
ATOM   1618 H HB3  . ASP A 1 105 ? 76.60578  -6.15255  6.89833  1.000 95.36311  ? 106 ASP A HB3  1 
ATOM   1619 N N    . LEU A 1 106 ? 79.54351  -8.32951  5.55938  1.000 72.66257  ? 107 LEU A N    1 
ATOM   1620 C CA   . LEU A 1 106 ? 80.90881  -8.00736  5.16339  1.000 73.68767  ? 107 LEU A CA   1 
ATOM   1621 C C    . LEU A 1 106 ? 81.02434  -6.59995  4.57378  1.000 74.22045  ? 107 LEU A C    1 
ATOM   1622 O O    . LEU A 1 106 ? 82.10010  -5.99503  4.61647  1.000 61.71196  ? 107 LEU A O    1 
ATOM   1623 C CB   . LEU A 1 106 ? 81.43520  -9.01584  4.13831  1.000 68.21683  ? 107 LEU A CB   1 
ATOM   1624 C CG   . LEU A 1 106 ? 81.70660  -10.42808 4.63217  1.000 62.79519  ? 107 LEU A CG   1 
ATOM   1625 C CD1  . LEU A 1 106 ? 82.19014  -11.30151 3.49010  1.000 61.53970  ? 107 LEU A CD1  1 
ATOM   1626 C CD2  . LEU A 1 106 ? 82.74372  -10.45660 5.75278  1.000 60.63490  ? 107 LEU A CD2  1 
ATOM   1627 H H    . LEU A 1 106 ? 79.20165  -9.00825  5.15684  1.000 87.26636  ? 107 LEU A H    1 
ATOM   1628 H HA   . LEU A 1 106 ? 81.45746  -8.06003  5.96158  1.000 88.49647  ? 107 LEU A HA   1 
ATOM   1629 H HB2  . LEU A 1 106 ? 80.78021  -9.08661  3.42636  1.000 81.93146  ? 107 LEU A HB2  1 
ATOM   1630 H HB3  . LEU A 1 106 ? 82.27202  -8.67399  3.78648  1.000 81.93146  ? 107 LEU A HB3  1 
ATOM   1631 H HG   . LEU A 1 106 ? 80.87395  -10.77819 4.98576  1.000 75.42549  ? 107 LEU A HG   1 
ATOM   1632 H HD11 . LEU A 1 106 ? 82.30685  -12.20847 3.81368  1.000 73.91890  ? 107 LEU A HD11 1 
ATOM   1633 H HD12 . LEU A 1 106 ? 81.53007  -11.28622 2.77948  1.000 73.91890  ? 107 LEU A HD12 1 
ATOM   1634 H HD13 . LEU A 1 106 ? 83.03550  -10.95536 3.16384  1.000 73.91890  ? 107 LEU A HD13 1 
ATOM   1635 H HD21 . LEU A 1 106 ? 82.93362  -11.37933 5.98391  1.000 72.83315  ? 107 LEU A HD21 1 
ATOM   1636 H HD22 . LEU A 1 106 ? 83.55311  -10.01935 5.44520  1.000 72.83315  ? 107 LEU A HD22 1 
ATOM   1637 H HD23 . LEU A 1 106 ? 82.38784  -9.98883  6.52443  1.000 72.83315  ? 107 LEU A HD23 1 
ATOM   1638 N N    . SER A 1 107 ? 79.95117  -6.07443  3.99143  1.000 80.07750  ? 108 SER A N    1 
ATOM   1639 C CA   . SER A 1 107 ? 80.01046  -4.73145  3.43638  1.000 76.33914  ? 108 SER A CA   1 
ATOM   1640 C C    . SER A 1 107 ? 79.97435  -3.68115  4.53406  1.000 76.94200  ? 108 SER A C    1 
ATOM   1641 O O    . SER A 1 107 ? 80.60662  -2.62951  4.39390  1.000 65.87315  ? 108 SER A O    1 
ATOM   1642 C CB   . SER A 1 107 ? 78.87548  -4.52675  2.43157  1.000 79.81333  ? 108 SER A CB   1 
ATOM   1643 O OG   . SER A 1 107 ? 77.62029  -4.84991  2.98737  1.000 80.57916  ? 108 SER A OG   1 
ATOM   1644 H H    . SER A 1 107 ? 79.19147  -6.46856  3.90708  1.000 96.16426  ? 108 SER A H    1 
ATOM   1645 H HA   . SER A 1 107 ? 80.83982  -4.61575  2.94681  1.000 91.67823  ? 108 SER A HA   1 
ATOM   1646 H HB2  . SER A 1 107 ? 78.86523  -3.59628  2.15767  1.000 95.84727  ? 108 SER A HB2  1 
ATOM   1647 H HB3  . SER A 1 107 ? 79.03256  -5.09715  1.66289  1.000 95.84727  ? 108 SER A HB3  1 
ATOM   1648 H HG   . SER A 1 107 ? 77.03592  -4.87109  2.38432  1.000 96.76626  ? 108 SER A HG   1 
ATOM   1649 N N    . ASP A 1 108 ? 79.26976  -3.96048  5.63513  1.000 90.74849  ? 109 ASP A N    1 
ATOM   1650 C CA   . ASP A 1 108 ? 79.31845  -3.09306  6.80701  1.000 85.64023  ? 109 ASP A CA   1 
ATOM   1651 C C    . ASP A 1 108 ? 80.75059  -2.93550  7.29945  1.000 73.58032  ? 109 ASP A C    1 
ATOM   1652 O O    . ASP A 1 108 ? 81.18434  -1.83470  7.66971  1.000 67.16018  ? 109 ASP A O    1 
ATOM   1653 C CB   . ASP A 1 108 ? 78.41085  -3.67985  7.87829  1.000 89.63503  ? 109 ASP A CB   1 
ATOM   1654 C CG   . ASP A 1 108 ? 78.37303  -2.84161  9.12616  1.000 97.04925  ? 109 ASP A CG   1 
ATOM   1655 O OD1  . ASP A 1 108 ? 77.65957  -3.24110  10.07904 1.000 84.46512  ? 109 ASP A OD1  1 
ATOM   1656 O OD2  . ASP A 1 108 ? 79.05593  -1.79500  9.15857  1.000 116.09225 ? 109 ASP A OD2  1 
ATOM   1657 H H    . ASP A 1 108 ? 78.75762  -4.64530  5.72651  1.000 108.96945 ? 109 ASP A H    1 
ATOM   1658 H HA   . ASP A 1 108 ? 78.99381  -2.20483  6.59125  1.000 102.83954 ? 109 ASP A HA   1 
ATOM   1659 H HB2  . ASP A 1 108 ? 77.50773  -3.74085  7.52963  1.000 107.63331 ? 109 ASP A HB2  1 
ATOM   1660 H HB3  . ASP A 1 108 ? 78.73400  -4.56231  8.11860  1.000 107.63331 ? 109 ASP A HB3  1 
ATOM   1661 N N    . LEU A 1 109 ? 81.51560  -4.02054  7.26171  1.000 67.60658  ? 110 LEU A N    1 
ATOM   1662 C CA   . LEU A 1 109 ? 82.88810  -3.95242  7.72743  1.000 64.61624  ? 110 LEU A CA   1 
ATOM   1663 C C    . LEU A 1 109 ? 83.71989  -3.02819  6.86308  1.000 67.39736  ? 110 LEU A C    1 
ATOM   1664 O O    . LEU A 1 109 ? 84.59063  -2.30811  7.36986  1.000 62.24717  ? 110 LEU A O    1 
ATOM   1665 C CB   . LEU A 1 109 ? 83.51271  -5.34555  7.75284  1.000 65.04682  ? 110 LEU A CB   1 
ATOM   1666 C CG   . LEU A 1 109 ? 85.02858  -5.40980  7.95993  1.000 61.72687  ? 110 LEU A CG   1 
ATOM   1667 C CD1  . LEU A 1 109 ? 85.50760  -4.90901  9.33630  1.000 64.84432  ? 110 LEU A CD1  1 
ATOM   1668 C CD2  . LEU A 1 109 ? 85.49590  -6.86934  7.76092  1.000 52.25174  ? 110 LEU A CD2  1 
ATOM   1669 H H    . LEU A 1 109 ? 81.26682  -4.79266  6.97615  1.000 81.19916  ? 110 LEU A H    1 
ATOM   1670 H HA   . LEU A 1 109 ? 82.88383  -3.60482  8.63300  1.000 77.61075  ? 110 LEU A HA   1 
ATOM   1671 H HB2  . LEU A 1 109 ? 83.10443  -5.84487  8.47734  1.000 78.12745  ? 110 LEU A HB2  1 
ATOM   1672 H HB3  . LEU A 1 109 ? 83.32220  -5.77593  6.90468  1.000 78.12745  ? 110 LEU A HB3  1 
ATOM   1673 H HG   . LEU A 1 109 ? 85.42924  -4.81196  7.30957  1.000 74.14352  ? 110 LEU A HG   1 
ATOM   1674 H HD11 . LEU A 1 109 ? 86.47677  -4.93853  9.36331  1.000 77.88445  ? 110 LEU A HD11 1 
ATOM   1675 H HD12 . LEU A 1 109 ? 85.20069  -3.99791  9.46519  1.000 77.88445  ? 110 LEU A HD12 1 
ATOM   1676 H HD13 . LEU A 1 109 ? 85.13982  -5.48270  10.02661 1.000 77.88445  ? 110 LEU A HD13 1 
ATOM   1677 H HD21 . LEU A 1 109 ? 86.01722  -6.92552  6.94484  1.000 62.77335  ? 110 LEU A HD21 1 
ATOM   1678 H HD22 . LEU A 1 109 ? 86.03970  -7.13305  8.51963  1.000 62.77335  ? 110 LEU A HD22 1 
ATOM   1679 H HD23 . LEU A 1 109 ? 84.71728  -7.44420  7.69627  1.000 62.77335  ? 110 LEU A HD23 1 
ATOM   1680 N N    . VAL A 1 110 ? 83.50841  -3.07637  5.54176  1.000 75.30485  ? 111 VAL A N    1 
ATOM   1681 C CA   . VAL A 1 110 ? 84.35852  -2.31938  4.63057  1.000 66.20897  ? 111 VAL A CA   1 
ATOM   1682 C C    . VAL A 1 110 ? 84.09985  -0.82781  4.75800  1.000 59.44519  ? 111 VAL A C    1 
ATOM   1683 O O    . VAL A 1 110 ? 85.02772  -0.01482  4.71981  1.000 58.74293  ? 111 VAL A O    1 
ATOM   1684 C CB   . VAL A 1 110 ? 84.15211  -2.76770  3.17109  1.000 77.14078  ? 111 VAL A CB   1 
ATOM   1685 C CG1  . VAL A 1 110 ? 85.17502  -2.01078  2.32983  1.000 85.50932  ? 111 VAL A CG1  1 
ATOM   1686 C CG2  . VAL A 1 110 ? 84.19517  -4.26059  3.04078  1.000 68.90337  ? 111 VAL A CG2  1 
ATOM   1687 H H    . VAL A 1 110 ? 82.88886  -3.53323  5.15831  1.000 90.43709  ? 111 VAL A H    1 
ATOM   1688 H HA   . VAL A 1 110 ? 85.27662  -2.50381  4.88351  1.000 79.52203  ? 111 VAL A HA   1 
ATOM   1689 H HB   . VAL A 1 110 ? 83.26820  -2.54874  2.83693  1.000 92.64020  ? 111 VAL A HB   1 
ATOM   1690 H HG11 . VAL A 1 110 ? 85.14902  -2.34915  1.42114  1.000 102.68246 ? 111 VAL A HG11 1 
ATOM   1691 H HG12 . VAL A 1 110 ? 84.95358  -1.06643  2.33761  1.000 102.68246 ? 111 VAL A HG12 1 
ATOM   1692 H HG13 . VAL A 1 110 ? 86.05776  -2.14667  2.70827  1.000 102.68246 ? 111 VAL A HG13 1 
ATOM   1693 H HG21 . VAL A 1 110 ? 84.10649  -4.49856  2.10461  1.000 82.75531  ? 111 VAL A HG21 1 
ATOM   1694 H HG22 . VAL A 1 110 ? 85.04255  -4.58335  3.38528  1.000 82.75531  ? 111 VAL A HG22 1 
ATOM   1695 H HG23 . VAL A 1 110 ? 83.46370  -4.64328  3.55008  1.000 82.75531  ? 111 VAL A HG23 1 
ATOM   1696 N N    . GLU A 1 111 ? 82.82892  -0.44720  4.81409  1.000 58.76963  ? 112 GLU A N    1 
ATOM   1697 C CA   . GLU A 1 111 ? 82.44437  0.91780   5.15084  1.000 71.08783  ? 112 GLU A CA   1 
ATOM   1698 C C    . GLU A 1 111 ? 83.18989  1.38674   6.40006  1.000 79.81655  ? 112 GLU A C    1 
ATOM   1699 O O    . GLU A 1 111 ? 83.94717  2.36573   6.35716  1.000 76.47901  ? 112 GLU A O    1 
ATOM   1700 C CB   . GLU A 1 111 ? 80.92739  0.94006   5.33959  1.000 82.05625  ? 112 GLU A CB   1 
ATOM   1701 C CG   . GLU A 1 111 ? 80.22363  2.17642   4.91797  1.000 87.39623  ? 112 GLU A CG   1 
ATOM   1702 C CD   . GLU A 1 111 ? 78.87373  1.85233   4.28618  1.000 94.34124  ? 112 GLU A CD   1 
ATOM   1703 O OE1  . GLU A 1 111 ? 77.86067  2.44152   4.73441  1.000 91.94346  ? 112 GLU A OE1  1 
ATOM   1704 O OE2  . GLU A 1 111 ? 78.82971  0.94255   3.40184  1.000 88.34997  ? 112 GLU A OE2  1 
ATOM   1705 H H    . GLU A 1 111 ? 82.16085  -0.96626  4.65959  1.000 70.59482  ? 112 GLU A H    1 
ATOM   1706 H HA   . GLU A 1 111 ? 82.67269  1.53479   4.43803  1.000 85.37666  ? 112 GLU A HA   1 
ATOM   1707 H HB2  . GLU A 1 111 ? 80.54966  0.20910   4.82587  1.000 98.53877  ? 112 GLU A HB2  1 
ATOM   1708 H HB3  . GLU A 1 111 ? 80.73985  0.81424   6.28294  1.000 98.53877  ? 112 GLU A HB3  1 
ATOM   1709 H HG2  . GLU A 1 111 ? 80.07246  2.74118   5.69198  1.000 104.94674 ? 112 GLU A HG2  1 
ATOM   1710 H HG3  . GLU A 1 111 ? 80.76333  2.64745   4.26393  1.000 104.94674 ? 112 GLU A HG3  1 
ATOM   1711 N N    . TRP A 1 112 ? 83.03349  0.64028   7.50694  1.000 77.78696  ? 113 TRP A N    1 
ATOM   1712 C CA   . TRP A 1 112 ? 83.60072  1.03892   8.79417  1.000 74.15125  ? 113 TRP A CA   1 
ATOM   1713 C C    . TRP A 1 112 ? 85.11276  1.20389   8.73430  1.000 68.48227  ? 113 TRP A C    1 
ATOM   1714 O O    . TRP A 1 112 ? 85.66243  2.18523   9.24106  1.000 66.12157  ? 113 TRP A O    1 
ATOM   1715 C CB   . TRP A 1 112 ? 83.22379  0.00165   9.85222  1.000 82.27913  ? 113 TRP A CB   1 
ATOM   1716 C CG   . TRP A 1 112 ? 83.79184  0.25565   11.21944 1.000 78.57501  ? 113 TRP A CG   1 
ATOM   1717 C CD1  . TRP A 1 112 ? 83.38071  1.19510   12.09998 1.000 70.68962  ? 113 TRP A CD1  1 
ATOM   1718 C CD2  . TRP A 1 112 ? 84.85191  -0.45907  11.86051 1.000 70.39870  ? 113 TRP A CD2  1 
ATOM   1719 N NE1  . TRP A 1 112 ? 84.11094  1.11526   13.23650 1.000 74.61607  ? 113 TRP A NE1  1 
ATOM   1720 C CE2  . TRP A 1 112 ? 85.02220  0.10404   13.12089 1.000 74.74120  ? 113 TRP A CE2  1 
ATOM   1721 C CE3  . TRP A 1 112 ? 85.66025  -1.52385  11.49126 1.000 70.52454  ? 113 TRP A CE3  1 
ATOM   1722 C CZ2  . TRP A 1 112 ? 85.97090  -0.35698  14.02102 1.000 73.91363  ? 113 TRP A CZ2  1 
ATOM   1723 C CZ3  . TRP A 1 112 ? 86.61686  -1.95837  12.35956 1.000 72.60878  ? 113 TRP A CZ3  1 
ATOM   1724 C CH2  . TRP A 1 112 ? 86.76305  -1.38342  13.62302 1.000 69.23464  ? 113 TRP A CH2  1 
ATOM   1725 H H    . TRP A 1 112 ? 82.60115  -0.10264  7.53420  1.000 93.41562  ? 113 TRP A H    1 
ATOM   1726 H HA   . TRP A 1 112 ? 83.22719  1.90007   9.03872  1.000 89.05277  ? 113 TRP A HA   1 
ATOM   1727 H HB2  . TRP A 1 112 ? 82.25762  -0.01375  9.93694  1.000 98.80623  ? 113 TRP A HB2  1 
ATOM   1728 H HB3  . TRP A 1 112 ? 83.54510  -0.86578  9.56031  1.000 98.80623  ? 113 TRP A HB3  1 
ATOM   1729 H HD1  . TRP A 1 112 ? 82.69667  1.80638   11.94726 1.000 84.89881  ? 113 TRP A HD1  1 
ATOM   1730 H HE1  . TRP A 1 112 ? 84.01609  1.62230   13.92462 1.000 89.61055  ? 113 TRP A HE1  1 
ATOM   1731 H HE3  . TRP A 1 112 ? 85.55129  -1.93493  10.66419 1.000 84.70071  ? 113 TRP A HE3  1 
ATOM   1732 H HZ2  . TRP A 1 112 ? 86.06053  0.02300   14.86510 1.000 88.76762  ? 113 TRP A HZ2  1 
ATOM   1733 H HZ3  . TRP A 1 112 ? 87.18291  -2.65108  12.10535 1.000 87.20180  ? 113 TRP A HZ3  1 
ATOM   1734 H HH2  . TRP A 1 112 ? 87.41427  -1.70950  14.20137 1.000 83.15283  ? 113 TRP A HH2  1 
ATOM   1735 N N    . SER A 1 113 ? 85.81019  0.25438   8.13414  1.000 70.86003  ? 114 SER A N    1 
ATOM   1736 C CA   . SER A 1 113 ? 87.26537  0.29639   8.20227  1.000 74.45621  ? 114 SER A CA   1 
ATOM   1737 C C    . SER A 1 113 ? 87.88093  1.33395   7.28160  1.000 76.14983  ? 114 SER A C    1 
ATOM   1738 O O    . SER A 1 113 ? 89.04905  1.67715   7.48665  1.000 73.16594  ? 114 SER A O    1 
ATOM   1739 C CB   . SER A 1 113 ? 87.86690  -1.07100  7.87516  1.000 65.25304  ? 114 SER A CB   1 
ATOM   1740 O OG   . SER A 1 113 ? 86.86336  -1.90076  7.30738  1.000 73.62095  ? 114 SER A OG   1 
ATOM   1741 H H    . SER A 1 113 ? 85.47813  -0.40568  7.69409  1.000 85.10330  ? 114 SER A H    1 
ATOM   1742 H HA   . SER A 1 113 ? 87.50497  0.52141   9.11488  1.000 89.41872  ? 114 SER A HA   1 
ATOM   1743 H HB2  . SER A 1 113 ? 88.59111  -0.96049  7.23939  1.000 78.37492  ? 114 SER A HB2  1 
ATOM   1744 H HB3  . SER A 1 113 ? 88.19981  -1.47953  8.68952  1.000 78.37492  ? 114 SER A HB3  1 
ATOM   1745 H HG   . SER A 1 113 ? 87.19641  -2.38441  6.70674  1.000 88.41640  ? 114 SER A HG   1 
ATOM   1746 N N    . ALA A 1 114 ? 87.11928  1.84599   6.29536  1.000 85.73152  ? 115 ALA A N    1 
ATOM   1747 C CA   . ALA A 1 114 ? 87.65069  2.84835   5.36948  1.000 85.25597  ? 115 ALA A CA   1 
ATOM   1748 C C    . ALA A 1 114 ? 88.04047  4.11540   6.11278  1.000 83.86546  ? 115 ALA A C    1 
ATOM   1749 O O    . ALA A 1 114 ? 89.04395  4.76806   5.78229  1.000 83.48661  ? 115 ALA A O    1 
ATOM   1750 C CB   . ALA A 1 114 ? 86.62745  3.17347   4.29382  1.000 102.24489 ? 115 ALA A CB   1 
ATOM   1751 H H    . ALA A 1 114 ? 86.30060  1.62853   6.14676  1.000 102.94909 ? 115 ALA A H    1 
ATOM   1752 H HA   . ALA A 1 114 ? 88.43752  2.48282   4.93569  1.000 102.37843 ? 115 ALA A HA   1 
ATOM   1753 H HB1  . ALA A 1 114 ? 87.03217  3.76700   3.64204  1.000 122.76514 ? 115 ALA A HB1  1 
ATOM   1754 H HB2  . ALA A 1 114 ? 86.34921  2.34993   3.86339  1.000 122.76514 ? 115 ALA A HB2  1 
ATOM   1755 H HB3  . ALA A 1 114 ? 85.86312  3.60615   4.70550  1.000 122.76514 ? 115 ALA A HB3  1 
ATOM   1756 N N    . THR A 1 115 ? 87.24544  4.47437   7.12272  1.000 91.79278  ? 116 THR A N    1 
ATOM   1757 C CA   . THR A 1 115 ? 87.55168  5.60369   7.97504  1.000 91.37534  ? 116 THR A CA   1 
ATOM   1758 C C    . THR A 1 115 ? 88.77245  5.37440   8.86325  1.000 84.27105  ? 116 THR A C    1 
ATOM   1759 O O    . THR A 1 115 ? 89.29304  6.34620   9.41833  1.000 78.21431  ? 116 THR A O    1 
ATOM   1760 C CB   . THR A 1 115 ? 86.36206  5.92506   8.88478  1.000 88.50133  ? 116 THR A CB   1 
ATOM   1761 O OG1  . THR A 1 115 ? 86.50049  5.18862   10.11441 1.000 89.08078  ? 116 THR A OG1  1 
ATOM   1762 C CG2  . THR A 1 115 ? 85.02200  5.52931   8.27930  1.000 82.45927  ? 116 THR A CG2  1 
ATOM   1763 H H    . THR A 1 115 ? 86.51546  4.07068   7.33193  1.000 110.22260 ? 116 THR A H    1 
ATOM   1764 H HA   . THR A 1 115 ? 87.72746  6.35990   7.39353  1.000 109.72168 ? 116 THR A HA   1 
ATOM   1765 H HB   . THR A 1 115 ? 86.35676  6.88457   9.02699  1.000 106.27286 ? 116 THR A HB   1 
ATOM   1766 H HG1  . THR A 1 115 ? 85.85432  5.35655   10.62417 1.000 106.96820 ? 116 THR A HG1  1 
ATOM   1767 H HG21 . THR A 1 115 ? 84.29811  5.82869   8.85136  1.000 99.02239  ? 116 THR A HG21 1 
ATOM   1768 H HG22 . THR A 1 115 ? 84.92037  5.93553   7.40433  1.000 99.02239  ? 116 THR A HG22 1 
ATOM   1769 H HG23 . THR A 1 115 ? 84.97170  4.56508   8.18647  1.000 99.02239  ? 116 THR A HG23 1 
ATOM   1770 N N    . ARG A 1 116 ? 89.22180  4.12666   9.04228  1.000 84.52797  ? 117 ARG A N    1 
ATOM   1771 C CA   . ARG A 1 116 ? 90.27463  3.82016   10.00870 1.000 73.16447  ? 117 ARG A CA   1 
ATOM   1772 C C    . ARG A 1 116 ? 91.66802  3.72390   9.38867  1.000 74.09117  ? 117 ARG A C    1 
ATOM   1773 O O    . ARG A 1 116 ? 92.64300  4.03099   10.08411 1.000 61.24267  ? 117 ARG A O    1 
ATOM   1774 C CB   . ARG A 1 116 ? 89.97226  2.50076   10.75136 1.000 72.67098  ? 117 ARG A CB   1 
ATOM   1775 C CG   . ARG A 1 116 ? 88.59918  2.41648   11.48838 1.000 75.70157  ? 117 ARG A CG   1 
ATOM   1776 C CD   . ARG A 1 116 ? 88.64531  1.50732   12.73936 1.000 75.14053  ? 117 ARG A CD   1 
ATOM   1777 N NE   . ARG A 1 116 ? 88.15306  2.20859   13.93109 1.000 96.38728  ? 117 ARG A NE   1 
ATOM   1778 C CZ   . ARG A 1 116 ? 88.61852  2.07702   15.17992 1.000 93.31344  ? 117 ARG A CZ   1 
ATOM   1779 N NH1  . ARG A 1 116 ? 89.65399  1.28020   15.47157 1.000 88.09760  ? 117 ARG A NH1  1 
ATOM   1780 N NH2  . ARG A 1 116 ? 88.02631  2.75948   16.16716 1.000 86.87072  ? 117 ARG A NH2  1 
ATOM   1781 H H    . ARG A 1 116 ? 88.92989  3.44087   8.61322  1.000 101.50483 ? 117 ARG A H    1 
ATOM   1782 H HA   . ARG A 1 116 ? 90.28988  4.53310   10.66625 1.000 87.86863  ? 117 ARG A HA   1 
ATOM   1783 H HB2  . ARG A 1 116 ? 89.99223  1.77904   10.10358 1.000 87.27644  ? 117 ARG A HB2  1 
ATOM   1784 H HB3  . ARG A 1 116 ? 90.66250  2.36611   11.41945 1.000 87.27644  ? 117 ARG A HB3  1 
ATOM   1785 H HG2  . ARG A 1 116 ? 88.33840  3.30598   11.77418 1.000 90.91316  ? 117 ARG A HG2  1 
ATOM   1786 H HG3  . ARG A 1 116 ? 87.93532  2.05547   10.88022 1.000 90.91316  ? 117 ARG A HG3  1 
ATOM   1787 H HD2  . ARG A 1 116 ? 88.08673  0.72827   12.59110 1.000 90.23990  ? 117 ARG A HD2  1 
ATOM   1788 H HD3  . ARG A 1 116 ? 89.56104  1.23262   12.90328 1.000 90.23990  ? 117 ARG A HD3  1 
ATOM   1789 H HE   . ARG A 1 116 ? 87.50158  2.75809   13.81608 1.000 115.73601 ? 117 ARG A HE   1 
ATOM   1790 H HH11 . ARG A 1 116 ? 90.04170  0.83318   14.84750 1.000 105.78839 ? 117 ARG A HH11 1 
ATOM   1791 H HH12 . ARG A 1 116 ? 89.93147  1.21534   16.28298 1.000 105.78839 ? 117 ARG A HH12 1 
ATOM   1792 H HH21 . ARG A 1 116 ? 87.35795  3.27242   15.99457 1.000 104.31613 ? 117 ARG A HH21 1 
ATOM   1793 H HH22 . ARG A 1 116 ? 88.31412  2.68509   16.97415 1.000 104.31613 ? 117 ARG A HH22 1 
ATOM   1794 N N    . TYR A 1 117 ? 91.79610  3.29930   8.12015  1.000 74.15415  ? 118 TYR A N    1 
ATOM   1795 C CA   . TYR A 1 117 ? 93.07879  3.22518   7.41851  1.000 76.42748  ? 118 TYR A CA   1 
ATOM   1796 C C    . TYR A 1 117 ? 92.78974  3.17312   5.91495  1.000 66.57073  ? 118 TYR A C    1 
ATOM   1797 O O    . TYR A 1 117 ? 91.66483  2.86223   5.49777  1.000 59.72970  ? 118 TYR A O    1 
ATOM   1798 C CB   . TYR A 1 117 ? 93.91981  2.00910   7.87694  1.000 66.87743  ? 118 TYR A CB   1 
ATOM   1799 C CG   . TYR A 1 117 ? 93.11322  0.72885   7.98320  1.000 67.50396  ? 118 TYR A CG   1 
ATOM   1800 C CD1  . TYR A 1 117 ? 92.80538  -0.04557  6.86693  1.000 74.00862  ? 118 TYR A CD1  1 
ATOM   1801 C CD2  . TYR A 1 117 ? 92.61627  0.31870   9.19456  1.000 72.71943  ? 118 TYR A CD2  1 
ATOM   1802 C CE1  . TYR A 1 117 ? 92.02719  -1.18677  6.97237  1.000 74.13360  ? 118 TYR A CE1  1 
ATOM   1803 C CE2  . TYR A 1 117 ? 91.85205  -0.82396  9.31613  1.000 70.77117  ? 118 TYR A CE2  1 
ATOM   1804 C CZ   . TYR A 1 117 ? 91.55006  -1.56861  8.20403  1.000 67.14445  ? 118 TYR A CZ   1 
ATOM   1805 O OH   . TYR A 1 117 ? 90.77837  -2.68852  8.35652  1.000 64.53267  ? 118 TYR A OH   1 
ATOM   1806 H H    . TYR A 1 117 ? 91.13402  3.04259   7.63501  1.000 89.05625  ? 118 TYR A H    1 
ATOM   1807 H HA   . TYR A 1 117 ? 93.60276  4.02034   7.60311  1.000 91.78425  ? 118 TYR A HA   1 
ATOM   1808 H HB2  . TYR A 1 117 ? 94.63206  1.86043   7.23546  1.000 80.32418  ? 118 TYR A HB2  1 
ATOM   1809 H HB3  . TYR A 1 117 ? 94.29491  2.19865   8.75116  1.000 80.32418  ? 118 TYR A HB3  1 
ATOM   1810 H HD1  . TYR A 1 117 ? 93.12920  0.20898   6.03312  1.000 88.88161  ? 118 TYR A HD1  1 
ATOM   1811 H HD2  . TYR A 1 117 ? 92.79924  0.82397   9.95359  1.000 87.33459  ? 118 TYR A HD2  1 
ATOM   1812 H HE1  . TYR A 1 117 ? 91.82909  -1.69057  6.21617  1.000 89.03158  ? 118 TYR A HE1  1 
ATOM   1813 H HE2  . TYR A 1 117 ? 91.54179  -1.08922  10.15176 1.000 84.99667  ? 118 TYR A HE2  1 
ATOM   1814 H HH   . TYR A 1 117 ? 90.52278  -2.75491  9.15394  1.000 77.51047  ? 118 TYR A HH   1 
ATOM   1815 N N    . ARG A 1 118 ? 93.80618  3.50560   5.10270  1.000 65.43337  ? 119 ARG A N    1 
ATOM   1816 C CA   . ARG A 1 118 ? 93.62411  3.37173   3.64403  1.000 74.81999  ? 119 ARG A CA   1 
ATOM   1817 C C    . ARG A 1 118 ? 93.49496  1.90422   3.27039  1.000 64.82765  ? 119 ARG A C    1 
ATOM   1818 O O    . ARG A 1 118 ? 92.47188  1.49081   2.72422  1.000 53.34683  ? 119 ARG A O    1 
ATOM   1819 C CB   . ARG A 1 118 ? 94.76231  4.00722   2.83871  1.000 56.56798  ? 119 ARG A CB   1 
ATOM   1820 C CG   . ARG A 1 118 ? 94.83288  5.51186   2.99289  1.000 63.90567  ? 119 ARG A CG   1 
ATOM   1821 C CD   . ARG A 1 118 ? 95.03143  6.33587   1.74456  1.000 75.32863  ? 119 ARG A CD   1 
ATOM   1822 N NE   . ARG A 1 118 ? 96.18713  5.90791   0.97772  1.000 80.25353  ? 119 ARG A NE   1 
ATOM   1823 C CZ   . ARG A 1 118 ? 96.15905  5.61854   -0.31870 1.000 68.30403  ? 119 ARG A CZ   1 
ATOM   1824 N NH1  . ARG A 1 118 ? 95.04365  5.69714   -1.02452 1.000 63.57359  ? 119 ARG A NH1  1 
ATOM   1825 N NH2  . ARG A 1 118 ? 97.27969  5.24303   -0.91632 1.000 67.65093  ? 119 ARG A NH2  1 
ATOM   1826 H H    . ARG A 1 118 ? 94.57453  3.79710   5.35622  1.000 78.59131  ? 119 ARG A H    1 
ATOM   1827 H HA   . ARG A 1 118 ? 92.81809  3.85785   3.40967  1.000 89.85525  ? 119 ARG A HA   1 
ATOM   1828 H HB2  . ARG A 1 118 ? 95.60608  3.63611   3.14073  1.000 67.95284  ? 119 ARG A HB2  1 
ATOM   1829 H HB3  . ARG A 1 118 ? 94.63041  3.80918   1.89834  1.000 67.95284  ? 119 ARG A HB3  1 
ATOM   1830 H HG2  . ARG A 1 118 ? 94.00080  5.80916   3.39309  1.000 76.75807  ? 119 ARG A HG2  1 
ATOM   1831 H HG3  . ARG A 1 118 ? 95.57592  5.71592   3.58208  1.000 76.75807  ? 119 ARG A HG3  1 
ATOM   1832 H HD2  . ARG A 1 118 ? 94.24715  6.25142   1.18005  1.000 90.46562  ? 119 ARG A HD2  1 
ATOM   1833 H HD3  . ARG A 1 118 ? 95.16224  7.26406   1.99403  1.000 90.46562  ? 119 ARG A HD3  1 
ATOM   1834 H HE   . ARG A 1 118 ? 96.93892  5.83704   1.38928  1.000 96.37551  ? 119 ARG A HE   1 
ATOM   1835 H HH11 . ARG A 1 118 ? 94.31116  5.94075   -0.64542 1.000 76.35958  ? 119 ARG A HH11 1 
ATOM   1836 H HH12 . ARG A 1 118 ? 95.05071  5.50465   -1.86267 1.000 76.35958  ? 119 ARG A HH12 1 
ATOM   1837 H HH21 . ARG A 1 118 ? 98.01026  5.18965   -0.46576 1.000 81.25238  ? 119 ARG A HH21 1 
ATOM   1838 H HH22 . ARG A 1 118 ? 97.27681  5.05258   -1.75497 1.000 81.25238  ? 119 ARG A HH22 1 
ATOM   1839 N N    . PHE A 1 119 ? 94.48471  1.09819   3.67006  1.000 64.70909  ? 120 PHE A N    1 
ATOM   1840 C CA   . PHE A 1 119 ? 94.54916  -0.33531  3.44871  1.000 61.82380  ? 120 PHE A CA   1 
ATOM   1841 C C    . PHE A 1 119 ? 95.41872  -0.96704  4.54464  1.000 60.93903  ? 120 PHE A C    1 
ATOM   1842 O O    . PHE A 1 119 ? 96.25350  -0.30684  5.18809  1.000 52.06880  ? 120 PHE A O    1 
ATOM   1843 C CB   . PHE A 1 119 ? 95.13237  -0.65712  2.05224  1.000 52.68320  ? 120 PHE A CB   1 
ATOM   1844 C CG   . PHE A 1 119 ? 96.60946  -0.36708  1.93563  1.000 49.02180  ? 120 PHE A CG   1 
ATOM   1845 C CD1  . PHE A 1 119 ? 97.55170  -1.34921  2.18272  1.000 51.63586  ? 120 PHE A CD1  1 
ATOM   1846 C CD2  . PHE A 1 119 ? 97.05483  0.93261   1.60480  1.000 49.58986  ? 120 PHE A CD2  1 
ATOM   1847 C CE1  . PHE A 1 119 ? 98.93445  -1.07088  2.11111  1.000 55.81776  ? 120 PHE A CE1  1 
ATOM   1848 C CE2  . PHE A 1 119 ? 98.41756  1.22398   1.53563  1.000 53.27083  ? 120 PHE A CE2  1 
ATOM   1849 C CZ   . PHE A 1 119 ? 99.37036  0.21299   1.78658  1.000 53.71964  ? 120 PHE A CZ   1 
ATOM   1850 H H    . PHE A 1 119 ? 95.17304  1.38345   4.09952  1.000 77.72217  ? 120 PHE A H    1 
ATOM   1851 H HA   . PHE A 1 119 ? 93.65717  -0.71132  3.51096  1.000 74.25983  ? 120 PHE A HA   1 
ATOM   1852 H HB2  . PHE A 1 119 ? 94.99909  -1.59992  1.86714  1.000 63.29110  ? 120 PHE A HB2  1 
ATOM   1853 H HB3  . PHE A 1 119 ? 94.67083  -0.12035  1.38909  1.000 63.29110  ? 120 PHE A HB3  1 
ATOM   1854 H HD1  . PHE A 1 119 ? 97.26953  -2.20833  2.39994  1.000 62.03430  ? 120 PHE A HD1  1 
ATOM   1855 H HD2  . PHE A 1 119 ? 96.43241  1.60146   1.43118  1.000 59.57910  ? 120 PHE A HD2  1 
ATOM   1856 H HE1  . PHE A 1 119 ? 99.55385  -1.74364  2.28035  1.000 67.05258  ? 120 PHE A HE1  1 
ATOM   1857 H HE2  . PHE A 1 119 ? 98.69843  2.08493   1.32403  1.000 63.99627  ? 120 PHE A HE2  1 
ATOM   1858 H HZ   . PHE A 1 119 ? 100.27964 0.40150   1.73591  1.000 64.53483  ? 120 PHE A HZ   1 
ATOM   1859 N N    . VAL A 1 120 ? 95.28313  -2.28353  4.68409  1.000 64.43307  ? 121 VAL A N    1 
ATOM   1860 C CA   . VAL A 1 120 ? 96.17345  -3.03406  5.55757  1.000 65.62123  ? 121 VAL A CA   1 
ATOM   1861 C C    . VAL A 1 120 ? 96.41080  -4.43885  5.00920  1.000 57.67514  ? 121 VAL A C    1 
ATOM   1862 O O    . VAL A 1 120 ? 95.56364  -5.03285  4.33399  1.000 58.97586  ? 121 VAL A O    1 
ATOM   1863 C CB   . VAL A 1 120 ? 95.58070  -3.02525  6.99121  1.000 69.90594  ? 121 VAL A CB   1 
ATOM   1864 C CG1  . VAL A 1 120 ? 94.44950  -4.04152  7.16174  1.000 55.02403  ? 121 VAL A CG1  1 
ATOM   1865 C CG2  . VAL A 1 120 ? 96.66107  -3.21287  7.99726  1.000 63.76482  ? 121 VAL A CG2  1 
ATOM   1866 H H    . VAL A 1 120 ? 94.68719  -2.75852  4.28554  1.000 77.39095  ? 121 VAL A H    1 
ATOM   1867 H HA   . VAL A 1 120 ? 97.05755  -2.63510  5.56710  1.000 78.81675  ? 121 VAL A HA   1 
ATOM   1868 H HB   . VAL A 1 120 ? 95.17583  -2.15765  7.14699  1.000 83.95840  ? 121 VAL A HB   1 
ATOM   1869 H HG11 . VAL A 1 120 ? 93.91771  -3.79539  7.93473  1.000 66.10010  ? 121 VAL A HG11 1 
ATOM   1870 H HG12 . VAL A 1 120 ? 93.89685  -4.03565  6.36459  1.000 66.10010  ? 121 VAL A HG12 1 
ATOM   1871 H HG13 . VAL A 1 120 ? 94.83356  -4.92275  7.29148  1.000 66.10010  ? 121 VAL A HG13 1 
ATOM   1872 H HG21 . VAL A 1 120 ? 96.31096  -3.72116  8.74557  1.000 76.58906  ? 121 VAL A HG21 1 
ATOM   1873 H HG22 . VAL A 1 120 ? 97.39591  -3.69392  7.58555  1.000 76.58906  ? 121 VAL A HG22 1 
ATOM   1874 H HG23 . VAL A 1 120 ? 96.96415  -2.34299  8.30115  1.000 76.58906  ? 121 VAL A HG23 1 
ATOM   1875 N N    . THR A 1 121 ? 97.60001  -4.94658  5.28949  1.000 55.29604  ? 122 THR A N    1 
ATOM   1876 C CA   . THR A 1 121 ? 98.08487  -6.21080  4.76919  1.000 61.67362  ? 122 THR A CA   1 
ATOM   1877 C C    . THR A 1 121 ? 98.67938  -7.03788  5.90349  1.000 58.35747  ? 122 THR A C    1 
ATOM   1878 O O    . THR A 1 121 ? 99.58549  -6.57848  6.62081  1.000 52.19619  ? 122 THR A O    1 
ATOM   1879 C CB   . THR A 1 121 ? 99.14132  -5.99047  3.68081  1.000 63.16007  ? 122 THR A CB   1 
ATOM   1880 O OG1  . THR A 1 121 ? 98.59095  -5.16305  2.65648  1.000 66.06245  ? 122 THR A OG1  1 
ATOM   1881 C CG2  . THR A 1 121 ? 99.62790  -7.32830  3.10330  1.000 62.69004  ? 122 THR A CG2  1 
ATOM   1882 H H    . THR A 1 121 ? 98.17004  -4.55813  5.80309  1.000 66.42651  ? 122 THR A H    1 
ATOM   1883 H HA   . THR A 1 121 ? 97.34051  -6.70395  4.39022  1.000 74.07961  ? 122 THR A HA   1 
ATOM   1884 H HB   . THR A 1 121 ? 99.91888  -5.54970  4.05769  1.000 75.86335  ? 122 THR A HB   1 
ATOM   1885 H HG1  . THR A 1 121 ? 98.50302  -4.37674  2.93859  1.000 79.34621  ? 122 THR A HG1  1 
ATOM   1886 H HG21 . THR A 1 121 ? 99.93008  -7.20503  2.18984  1.000 75.29932  ? 122 THR A HG21 1 
ATOM   1887 H HG22 . THR A 1 121 ? 100.36345 -7.67112  3.63465  1.000 75.29932  ? 122 THR A HG22 1 
ATOM   1888 H HG23 . THR A 1 121 ? 98.90540  -7.97547  3.11124  1.000 75.29932  ? 122 THR A HG23 1 
ATOM   1889 N N    . LYS A 1 122 ? 98.19694  -8.27669  6.03872  1.000 54.74515  ? 123 LYS A N    1 
ATOM   1890 C CA   . LYS A 1 122 ? 98.63982  -9.13461  7.13938  1.000 52.29013  ? 123 LYS A CA   1 
ATOM   1891 C C    . LYS A 1 122 ? 99.88001  -9.94224  6.76203  1.000 50.68177  ? 123 LYS A C    1 
ATOM   1892 O O    . LYS A 1 122 ? 99.94348  -10.55249 5.67735  1.000 55.86079  ? 123 LYS A O    1 
ATOM   1893 C CB   . LYS A 1 122 ? 97.54255  -10.10414 7.58061  1.000 46.14905  ? 123 LYS A CB   1 
ATOM   1894 C CG   . LYS A 1 122 ? 96.47274  -9.46499  8.34703  1.000 53.07713  ? 123 LYS A CG   1 
ATOM   1895 C CD   . LYS A 1 122 ? 95.49783  -10.48396 8.90321  1.000 56.98847  ? 123 LYS A CD   1 
ATOM   1896 C CE   . LYS A 1 122 ? 94.36500  -10.58862 7.92564  1.000 68.08306  ? 123 LYS A CE   1 
ATOM   1897 N NZ   . LYS A 1 122 ? 93.37898  -9.53124  8.24030  1.000 66.45178  ? 123 LYS A NZ   1 
ATOM   1898 H H    . LYS A 1 122 ? 97.62013  -8.63707  5.51239  1.000 65.76545  ? 123 LYS A H    1 
ATOM   1899 H HA   . LYS A 1 122 ? 98.86468  -8.54740  7.87798  1.000 62.81942  ? 123 LYS A HA   1 
ATOM   1900 H HB2  . LYS A 1 122 ? 97.14447  -10.50564 6.79243  1.000 55.45013  ? 123 LYS A HB2  1 
ATOM   1901 H HB3  . LYS A 1 122 ? 97.93846  -10.79140 8.13903  1.000 55.45013  ? 123 LYS A HB3  1 
ATOM   1902 H HG2  . LYS A 1 122 ? 96.85883  -8.97597  9.09046  1.000 63.76382  ? 123 LYS A HG2  1 
ATOM   1903 H HG3  . LYS A 1 122 ? 95.98278  -8.85867  7.76978  1.000 63.76382  ? 123 LYS A HG3  1 
ATOM   1904 H HD2  . LYS A 1 122 ? 95.92773  -11.34877 8.99363  1.000 68.45743  ? 123 LYS A HD2  1 
ATOM   1905 H HD3  . LYS A 1 122 ? 95.15695  -10.19141 9.76293  1.000 68.45743  ? 123 LYS A HD3  1 
ATOM   1906 H HE2  . LYS A 1 122 ? 94.69220  -10.45969 7.02164  1.000 81.77094  ? 123 LYS A HE2  1 
ATOM   1907 H HE3  . LYS A 1 122 ? 93.93726  -11.45576 8.00314  1.000 81.77094  ? 123 LYS A HE3  1 
ATOM   1908 H HZ1  . LYS A 1 122 ? 92.60499  -9.70725  7.83774  1.000 79.81341  ? 123 LYS A HZ1  1 
ATOM   1909 H HZ2  . LYS A 1 122 ? 93.24498  -9.49182  9.11927  1.000 79.81341  ? 123 LYS A HZ2  1 
ATOM   1910 H HZ3  . LYS A 1 122 ? 93.67843  -8.74207  7.95810  1.000 79.81341  ? 123 LYS A HZ3  1 
ATOM   1911 N N    . THR A 1 123 ? 100.84342 -9.93553  7.66161  1.000 50.86036  ? 124 THR A N    1 
ATOM   1912 C CA   . THR A 1 123 ? 101.93388 -10.89031 7.74327  1.000 53.82688  ? 124 THR A CA   1 
ATOM   1913 C C    . THR A 1 123 ? 101.66222 -11.81765 8.93462  1.000 55.47915  ? 124 THR A C    1 
ATOM   1914 O O    . THR A 1 123 ? 101.51568 -11.34699 10.06923 1.000 54.76751  ? 124 THR A O    1 
ATOM   1915 C CB   . THR A 1 123 ? 103.25906 -10.16721 7.96546  1.000 51.04935  ? 124 THR A CB   1 
ATOM   1916 O OG1  . THR A 1 123 ? 103.56499 -9.32966  6.85031  1.000 55.03532  ? 124 THR A OG1  1 
ATOM   1917 C CG2  . THR A 1 123 ? 104.34319 -11.19159 8.21741  1.000 49.52770  ? 124 THR A CG2  1 
ATOM   1918 H H    . THR A 1 123 ? 100.89239 -9.34334  8.28332  1.000 61.10370  ? 124 THR A H    1 
ATOM   1919 H HA   . THR A 1 123 ? 101.98158 -11.40867 6.92478  1.000 64.66352  ? 124 THR A HA   1 
ATOM   1920 H HB   . THR A 1 123 ? 103.20948 -9.58679  8.74106  1.000 61.33048  ? 124 THR A HB   1 
ATOM   1921 H HG1  . THR A 1 123 ? 104.24112 -8.86098  7.01995  1.000 66.11365  ? 124 THR A HG1  1 
ATOM   1922 H HG21 . THR A 1 123 ? 105.20458 -10.83612 7.94805  1.000 59.50451  ? 124 THR A HG21 1 
ATOM   1923 H HG22 . THR A 1 123 ? 104.37586 -11.41489 9.16080  1.000 59.50451  ? 124 THR A HG22 1 
ATOM   1924 H HG23 . THR A 1 123 ? 104.16246 -11.99777 7.70917  1.000 59.50451  ? 124 THR A HG23 1 
ATOM   1925 N N    . TYR A 1 124 ? 101.63955 -13.12419 8.69181  1.000 51.05887  ? 125 TYR A N    1 
ATOM   1926 C CA   . TYR A 1 124 ? 101.26325 -14.09262 9.70663  1.000 53.20545  ? 125 TYR A CA   1 
ATOM   1927 C C    . TYR A 1 124 ? 102.50572 -14.61680 10.40883 1.000 54.95852  ? 125 TYR A C    1 
ATOM   1928 O O    . TYR A 1 124 ? 103.45830 -15.06621 9.76487  1.000 50.70973  ? 125 TYR A O    1 
ATOM   1929 C CB   . TYR A 1 124 ? 100.45714 -15.24788 9.10782  1.000 46.89408  ? 125 TYR A CB   1 
ATOM   1930 C CG   . TYR A 1 124 ? 99.13384  -14.80512 8.54278  1.000 47.79682  ? 125 TYR A CG   1 
ATOM   1931 C CD1  . TYR A 1 124 ? 97.99921  -14.72298 9.33827  1.000 48.68393  ? 125 TYR A CD1  1 
ATOM   1932 C CD2  . TYR A 1 124 ? 99.03474  -14.42062 7.20962  1.000 48.38650  ? 125 TYR A CD2  1 
ATOM   1933 C CE1  . TYR A 1 124 ? 96.77675  -14.28811 8.79987  1.000 53.88966  ? 125 TYR A CE1  1 
ATOM   1934 C CE2  . TYR A 1 124 ? 97.81893  -13.98011 6.64814  1.000 48.80900  ? 125 TYR A CE2  1 
ATOM   1935 C CZ   . TYR A 1 124 ? 96.69887  -13.92406 7.45171  1.000 53.25075  ? 125 TYR A CZ   1 
ATOM   1936 O OH   . TYR A 1 124 ? 95.49769  -13.50894 6.91362  1.000 58.84615  ? 125 TYR A OH   1 
ATOM   1937 H H    . TYR A 1 124 ? 101.84172 -13.47693 7.93398  1.000 61.34191  ? 125 TYR A H    1 
ATOM   1938 H HA   . TYR A 1 124 ? 100.70116 -13.65446 10.36464 1.000 63.91781  ? 125 TYR A HA   1 
ATOM   1939 H HB2  . TYR A 1 124 ? 100.96985 -15.65168 8.39019  1.000 56.34417  ? 125 TYR A HB2  1 
ATOM   1940 H HB3  . TYR A 1 124 ? 100.28312 -15.90375 9.80097  1.000 56.34417  ? 125 TYR A HB3  1 
ATOM   1941 H HD1  . TYR A 1 124 ? 98.04885  -14.95821 10.23666 1.000 58.49198  ? 125 TYR A HD1  1 
ATOM   1942 H HD2  . TYR A 1 124 ? 99.79325  -14.45518 6.67262  1.000 58.13507  ? 125 TYR A HD2  1 
ATOM   1943 H HE1  . TYR A 1 124 ? 96.02039  -14.24235 9.33906  1.000 64.73886  ? 125 TYR A HE1  1 
ATOM   1944 H HE2  . TYR A 1 124 ? 97.77279  -13.73200 5.75303  1.000 58.64207  ? 125 TYR A HE2  1 
ATOM   1945 H HH   . TYR A 1 124 ? 94.90231  -13.50847 7.50618  1.000 70.68664  ? 125 TYR A HH   1 
ATOM   1946 N N    . ASP A 1 125 ? 102.50199 -14.51909 11.74406 1.000 53.14883  ? 126 ASP A N    1 
ATOM   1947 C CA   . ASP A 1 125 ? 103.54544 -15.15416 12.53744 1.000 61.14006  ? 126 ASP A CA   1 
ATOM   1948 C C    . ASP A 1 125 ? 103.17131 -16.58059 12.91377 1.000 57.58756  ? 126 ASP A C    1 
ATOM   1949 O O    . ASP A 1 125 ? 104.07008 -17.44432 12.96768 1.000 53.05428  ? 126 ASP A O    1 
ATOM   1950 C CB   . ASP A 1 125 ? 103.87105 -14.35236 13.79366 1.000 66.26122  ? 126 ASP A CB   1 
ATOM   1951 C CG   . ASP A 1 125 ? 104.80201 -13.12712 13.48738 1.000 70.89722  ? 126 ASP A CG   1 
ATOM   1952 O OD1  . ASP A 1 125 ? 104.89437 -12.22325 14.34813 1.000 81.67664  ? 126 ASP A OD1  1 
ATOM   1953 O OD2  . ASP A 1 125 ? 105.45497 -13.07324 12.40719 1.000 77.85701  ? 126 ASP A OD2  1 
ATOM   1954 H H    . ASP A 1 125 ? 101.91116 -14.09473 12.20280 1.000 63.84987  ? 126 ASP A H    1 
ATOM   1955 H HA   . ASP A 1 125 ? 104.36297 -15.17054 12.01562 1.000 73.43934  ? 126 ASP A HA   1 
ATOM   1956 H HB2  . ASP A 1 125 ? 103.04695 -14.01718 14.18019 1.000 79.58473  ? 126 ASP A HB2  1 
ATOM   1957 H HB3  . ASP A 1 125 ? 104.32603 -14.92678 14.42922 1.000 79.58473  ? 126 ASP A HB3  1 
ATOM   1958 N N    . ARG A 1 126 ? 101.86686 -16.86806 13.07345 1.000 48.90544  ? 127 ARG A N    1 
ATOM   1959 C CA   . ARG A 1 126 ? 101.48367 -18.19416 13.52207 1.000 45.22294  ? 127 ARG A CA   1 
ATOM   1960 C C    . ARG A 1 126 ? 99.99403  -18.42228 13.41581 1.000 51.97446  ? 127 ARG A C    1 
ATOM   1961 O O    . ARG A 1 126 ? 99.18839  -17.52192 13.65267 1.000 54.50657  ? 127 ARG A O    1 
ATOM   1962 C CB   . ARG A 1 126 ? 101.90902 -18.36314 14.98564 1.000 63.93732  ? 127 ARG A CB   1 
ATOM   1963 C CG   . ARG A 1 126 ? 101.48247 -19.61672 15.61694 1.000 62.44800  ? 127 ARG A CG   1 
ATOM   1964 C CD   . ARG A 1 126 ? 102.71613 -20.23578 16.08925 1.000 61.26671  ? 127 ARG A CD   1 
ATOM   1965 N NE   . ARG A 1 126 ? 102.37623 -21.23485 17.08090 1.000 72.61925  ? 127 ARG A NE   1 
ATOM   1966 C CZ   . ARG A 1 126 ? 103.28275 -21.88249 17.78441 1.000 69.26712  ? 127 ARG A CZ   1 
ATOM   1967 N NH1  . ARG A 1 126 ? 104.57947 -21.63514 17.61545 1.000 70.04884  ? 127 ARG A NH1  1 
ATOM   1968 N NH2  . ARG A 1 126 ? 102.87973 -22.79169 18.67240 1.000 71.35510  ? 127 ARG A NH2  1 
ATOM   1969 H H    . ARG A 1 126 ? 101.21705 -16.32319 12.93039 1.000 58.75779  ? 127 ARG A H    1 
ATOM   1970 H HA   . ARG A 1 126 ? 101.89922 -18.84957 12.94014 1.000 54.33879  ? 127 ARG A HA   1 
ATOM   1971 H HB2  . ARG A 1 126 ? 102.87751 -18.33099 15.02909 1.000 76.79605  ? 127 ARG A HB2  1 
ATOM   1972 H HB3  . ARG A 1 126 ? 101.52942 -17.63449 15.50129 1.000 76.79605  ? 127 ARG A HB3  1 
ATOM   1973 H HG2  . ARG A 1 126 ? 100.88997 -19.44351 16.36516 1.000 75.00887  ? 127 ARG A HG2  1 
ATOM   1974 H HG3  . ARG A 1 126 ? 101.04458 -20.19654 14.97431 1.000 75.00887  ? 127 ARG A HG3  1 
ATOM   1975 H HD2  . ARG A 1 126 ? 103.17711 -20.66438 15.35121 1.000 73.59132  ? 127 ARG A HD2  1 
ATOM   1976 H HD3  . ARG A 1 126 ? 103.28971 -19.56715 16.49525 1.000 73.59132  ? 127 ARG A HD3  1 
ATOM   1977 H HE   . ARG A 1 126 ? 101.54598 -21.41335 17.21665 1.000 87.21436  ? 127 ARG A HE   1 
ATOM   1978 H HH11 . ARG A 1 126 ? 104.83387 -21.04695 17.04195 1.000 84.12988  ? 127 ARG A HH11 1 
ATOM   1979 H HH12 . ARG A 1 126 ? 105.16300 -22.06350 18.07978 1.000 84.12988  ? 127 ARG A HH12 1 
ATOM   1980 H HH21 . ARG A 1 126 ? 102.04050 -22.94692 18.77821 1.000 85.69738  ? 127 ARG A HH21 1 
ATOM   1981 H HH22 . ARG A 1 126 ? 103.45901 -23.22293 19.13939 1.000 85.69738  ? 127 ARG A HH22 1 
ATOM   1982 N N    . PHE A 1 127 ? 99.65407  -19.66450 13.10441 1.000 51.40305  ? 128 PHE A N    1 
ATOM   1983 C CA   . PHE A 1 127 ? 98.31860  -20.24404 13.24556 1.000 49.12178  ? 128 PHE A CA   1 
ATOM   1984 C C    . PHE A 1 127 ? 98.37425  -21.32446 14.33454 1.000 57.44218  ? 128 PHE A C    1 
ATOM   1985 O O    . PHE A 1 127 ? 99.27960  -22.17613 14.32999 1.000 61.14540  ? 128 PHE A O    1 
ATOM   1986 C CB   . PHE A 1 127 ? 97.85785  -20.85851 11.91069 1.000 53.18780  ? 128 PHE A CB   1 
ATOM   1987 C CG   . PHE A 1 127 ? 97.21539  -19.87577 10.94817 1.000 49.21913  ? 128 PHE A CG   1 
ATOM   1988 C CD1  . PHE A 1 127 ? 97.98728  -19.02142 10.15641 1.000 46.35452  ? 128 PHE A CD1  1 
ATOM   1989 C CD2  . PHE A 1 127 ? 95.82826  -19.83076 10.82027 1.000 53.87056  ? 128 PHE A CD2  1 
ATOM   1990 C CE1  . PHE A 1 127 ? 97.38538  -18.09842 9.27845  1.000 43.61779  ? 128 PHE A CE1  1 
ATOM   1991 C CE2  . PHE A 1 127 ? 95.19492  -18.93399 9.93909  1.000 50.54977  ? 128 PHE A CE2  1 
ATOM   1992 C CZ   . PHE A 1 127 ? 95.97810  -18.06743 9.17109  1.000 46.91659  ? 128 PHE A CZ   1 
ATOM   1993 H H    . PHE A 1 127 ? 100.21589 -20.23316 12.78725 1.000 61.75493  ? 128 PHE A H    1 
ATOM   1994 H HA   . PHE A 1 127 ? 97.67760  -19.56494 13.50795 1.000 59.01740  ? 128 PHE A HA   1 
ATOM   1995 H HB2  . PHE A 1 127 ? 98.62958  -21.24160 11.46506 1.000 63.89662  ? 128 PHE A HB2  1 
ATOM   1996 H HB3  . PHE A 1 127 ? 97.20571  -21.55141 12.09914 1.000 63.89662  ? 128 PHE A HB3  1 
ATOM   1997 H HD1  . PHE A 1 127 ? 98.91482  -19.06281 10.20993 1.000 55.69669  ? 128 PHE A HD1  1 
ATOM   1998 H HD2  . PHE A 1 127 ? 95.30747  -20.40823 11.33038 1.000 64.71593  ? 128 PHE A HD2  1 
ATOM   1999 H HE1  . PHE A 1 127 ? 97.90872  -17.51672 8.77582  1.000 52.41261  ? 128 PHE A HE1  1 
ATOM   2000 H HE2  . PHE A 1 127 ? 94.26771  -18.91829 9.86882  1.000 60.73100  ? 128 PHE A HE2  1 
ATOM   2001 H HZ   . PHE A 1 127 ? 95.57079  -17.46864 8.58761  1.000 56.37118  ? 128 PHE A HZ   1 
ATOM   2002 N N    . ASP A 1 128 ? 97.45906  -21.25204 15.30528 1.000 50.54871  ? 129 ASP A N    1 
ATOM   2003 C CA   . ASP A 1 128 ? 97.26887  -22.29681 16.30469 1.000 50.50454  ? 129 ASP A CA   1 
ATOM   2004 C C    . ASP A 1 128 ? 95.82617  -22.77792 16.19878 1.000 55.97932  ? 129 ASP A C    1 
ATOM   2005 O O    . ASP A 1 128 ? 94.89266  -21.97432 16.04508 1.000 52.30405  ? 129 ASP A O    1 
ATOM   2006 C CB   . ASP A 1 128 ? 97.52374  -21.82756 17.76193 1.000 46.80797  ? 129 ASP A CB   1 
ATOM   2007 C CG   . ASP A 1 128 ? 99.03287  -21.70050 18.11130 1.000 53.70304  ? 129 ASP A CG   1 
ATOM   2008 O OD1  . ASP A 1 128 ? 99.85617  -22.49793 17.56489 1.000 60.23993  ? 129 ASP A OD1  1 
ATOM   2009 O OD2  . ASP A 1 128 ? 99.37176  -20.80311 18.91685 1.000 50.34259  ? 129 ASP A OD2  1 
ATOM   2010 H H    . ASP A 1 128 ? 96.92326  -20.58674 15.40477 1.000 60.72972  ? 129 ASP A H    1 
ATOM   2011 H HA   . ASP A 1 128 ? 97.90004  -23.01191 16.12818 1.000 60.67672  ? 129 ASP A HA   1 
ATOM   2012 H HB2  . ASP A 1 128 ? 97.11473  -20.95704 17.88766 1.000 56.24083  ? 129 ASP A HB2  1 
ATOM   2013 H HB3  . ASP A 1 128 ? 97.12995  -22.47041 18.37232 1.000 56.24083  ? 129 ASP A HB3  1 
ATOM   2014 N N    . THR A 1 129 ? 95.62818  -24.08396 16.29164 1.000 55.18846  ? 130 THR A N    1 
ATOM   2015 C CA   . THR A 1 129 ? 94.28447  -24.65055 16.33136 1.000 49.71306  ? 130 THR A CA   1 
ATOM   2016 C C    . THR A 1 129 ? 94.03660  -25.21630 17.73405 1.000 56.68512  ? 130 THR A C    1 
ATOM   2017 O O    . THR A 1 129 ? 94.85951  -25.97009 18.27078 1.000 53.71930  ? 130 THR A O    1 
ATOM   2018 C CB   . THR A 1 129 ? 94.08563  -25.72478 15.24563 1.000 55.29869  ? 130 THR A CB   1 
ATOM   2019 O OG1  . THR A 1 129 ? 94.41996  -25.19576 13.93629 1.000 52.37462  ? 130 THR A OG1  1 
ATOM   2020 C CG2  . THR A 1 129 ? 92.60919  -26.19625 15.27570 1.000 51.05585  ? 130 THR A CG2  1 
ATOM   2021 H H    . THR A 1 129 ? 96.25880  -24.66720 16.33343 1.000 66.29742  ? 130 THR A H    1 
ATOM   2022 H HA   . THR A 1 129 ? 93.62654  -23.95873 16.15988 1.000 59.72693  ? 130 THR A HA   1 
ATOM   2023 H HB   . THR A 1 129 ? 94.66753  -26.48304 15.41096 1.000 66.42970  ? 130 THR A HB   1 
ATOM   2024 H HG1  . THR A 1 129 ? 94.17488  -25.73250 13.33842 1.000 62.92081  ? 130 THR A HG1  1 
ATOM   2025 H HG21 . THR A 1 129 ? 92.40569  -26.70100 14.47276 1.000 61.33829  ? 130 THR A HG21 1 
ATOM   2026 H HG22 . THR A 1 129 ? 92.45694  -26.76093 16.04956 1.000 61.33829  ? 130 THR A HG22 1 
ATOM   2027 H HG23 . THR A 1 129 ? 92.01700  -25.42952 15.32410 1.000 61.33829  ? 130 THR A HG23 1 
ATOM   2028 N N    . ALA A 1 130 ? 92.90650  -24.84598 18.31175 1.000 52.13574  ? 131 ALA A N    1 
ATOM   2029 C CA   . ALA A 1 130 ? 92.46894  -25.27724 19.62127 1.000 51.42927  ? 131 ALA A CA   1 
ATOM   2030 C C    . ALA A 1 130 ? 91.35341  -26.28996 19.39845 1.000 55.85642  ? 131 ALA A C    1 
ATOM   2031 O O    . ALA A 1 130 ? 90.22225  -25.90784 19.07575 1.000 55.61648  ? 131 ALA A O    1 
ATOM   2032 C CB   . ALA A 1 130 ? 91.97185  -24.10417 20.47184 1.000 49.89905  ? 131 ALA A CB   1 
ATOM   2033 H H    . ALA A 1 130 ? 92.34401  -24.31248 17.93948 1.000 62.63415  ? 131 ALA A H    1 
ATOM   2034 H HA   . ALA A 1 130 ? 93.21208  -25.69133 20.08729 1.000 61.78639  ? 131 ALA A HA   1 
ATOM   2035 H HB1  . ALA A 1 130 ? 91.64961  -24.44419 21.32122 1.000 59.95013  ? 131 ALA A HB1  1 
ATOM   2036 H HB2  . ALA A 1 130 ? 92.70604  -23.48766 20.61942 1.000 59.95013  ? 131 ALA A HB2  1 
ATOM   2037 H HB3  . ALA A 1 130 ? 91.25246  -23.65516 20.00092 1.000 59.95013  ? 131 ALA A HB3  1 
ATOM   2038 N N    . ALA A 1 131 ? 91.67213  -27.57931 19.56601 1.000 59.19752  ? 132 ALA A N    1 
ATOM   2039 C CA   . ALA A 1 131 ? 90.64357  -28.61606 19.53718 1.000 55.32883  ? 132 ALA A CA   1 
ATOM   2040 C C    . ALA A 1 131 ? 89.71858  -28.43534 20.73521 1.000 49.34201  ? 132 ALA A C    1 
ATOM   2041 O O    . ALA A 1 131 ? 90.16549  -28.41477 21.88347 1.000 56.09888  ? 132 ALA A O    1 
ATOM   2042 C CB   . ALA A 1 131 ? 91.27050  -30.00196 19.56863 1.000 55.35711  ? 132 ALA A CB   1 
ATOM   2043 H H    . ALA A 1 131 ? 92.46981  -27.87305 19.69648 1.000 71.10829  ? 132 ALA A H    1 
ATOM   2044 H HA   . ALA A 1 131 ? 90.13327  -28.53634 18.71613 1.000 66.46587  ? 132 ALA A HA   1 
ATOM   2045 H HB1  . ALA A 1 131 ? 90.57261  -30.66681 19.45993 1.000 66.49980  ? 132 ALA A HB1  1 
ATOM   2046 H HB2  . ALA A 1 131 ? 91.91230  -30.07474 18.84497 1.000 66.49980  ? 132 ALA A HB2  1 
ATOM   2047 H HB3  . ALA A 1 131 ? 91.71699  -30.12734 20.42059 1.000 66.49980  ? 132 ALA A HB3  1 
ATOM   2048 N N    . THR A 1 132 ? 88.43949  -28.27547 20.47861 1.000 54.37264  ? 133 THR A N    1 
ATOM   2049 C CA   . THR A 1 132 ? 87.46382  -28.28067 21.55234 1.000 53.41843  ? 133 THR A CA   1 
ATOM   2050 C C    . THR A 1 132 ? 86.42010  -29.33630 21.21427 1.000 56.00602  ? 133 THR A C    1 
ATOM   2051 O O    . THR A 1 132 ? 86.41497  -29.90993 20.12690 1.000 56.41346  ? 133 THR A O    1 
ATOM   2052 C CB   . THR A 1 132 ? 86.80163  -26.88579 21.74387 1.000 50.71366  ? 133 THR A CB   1 
ATOM   2053 O OG1  . THR A 1 132 ? 85.65078  -26.77265 20.89549 1.000 53.37676  ? 133 THR A OG1  1 
ATOM   2054 C CG2  . THR A 1 132 ? 87.80931  -25.76461 21.48283 1.000 49.41206  ? 133 THR A CG2  1 
ATOM   2055 H H    . THR A 1 132 ? 88.10944  -28.16212 19.69260 1.000 65.31844  ? 133 THR A H    1 
ATOM   2056 H HA   . THR A 1 132 ? 87.88929  -28.50656 22.39427 1.000 64.17339  ? 133 THR A HA   1 
ATOM   2057 H HB   . THR A 1 132 ? 86.50443  -26.78339 22.66152 1.000 60.92766  ? 133 THR A HB   1 
ATOM   2058 H HG1  . THR A 1 132 ? 85.33400  -25.99613 20.94308 1.000 64.12338  ? 133 THR A HG1  1 
ATOM   2059 H HG21 . THR A 1 132 ? 87.39904  -24.90287 21.65595 1.000 59.36574  ? 133 THR A HG21 1 
ATOM   2060 H HG22 . THR A 1 132 ? 88.57942  -25.86892 22.06329 1.000 59.36574  ? 133 THR A HG22 1 
ATOM   2061 H HG23 . THR A 1 132 ? 88.10501  -25.79267 20.55943 1.000 59.36574  ? 133 THR A HG23 1 
ATOM   2062 N N    . LEU A 1 133 ? 85.51187  -29.56478 22.14433 1.000 56.09748  ? 134 LEU A N    1 
ATOM   2063 C CA   . LEU A 1 133 ? 84.39221  -30.47267 21.93848 1.000 62.92343  ? 134 LEU A CA   1 
ATOM   2064 C C    . LEU A 1 133 ? 83.22356  -29.83291 21.20043 1.000 60.83332  ? 134 LEU A C    1 
ATOM   2065 O O    . LEU A 1 133 ? 82.18323  -30.49282 21.05359 1.000 64.59550  ? 134 LEU A O    1 
ATOM   2066 C CB   . LEU A 1 133 ? 83.91273  -31.01614 23.29719 1.000 67.07198  ? 134 LEU A CB   1 
ATOM   2067 C CG   . LEU A 1 133 ? 85.00881  -31.58921 24.18420 1.000 64.02164  ? 134 LEU A CG   1 
ATOM   2068 C CD1  . LEU A 1 133 ? 84.56680  -31.60942 25.65992 1.000 69.44611  ? 134 LEU A CD1  1 
ATOM   2069 C CD2  . LEU A 1 133 ? 85.46936  -32.98931 23.82816 1.000 63.44093  ? 134 LEU A CD2  1 
ATOM   2070 H H    . LEU A 1 133 ? 85.51894  -29.19921 22.92273 1.000 67.38824  ? 134 LEU A H    1 
ATOM   2071 H HA   . LEU A 1 133 ? 84.69624  -31.22060 21.40082 1.000 75.57938  ? 134 LEU A HA   1 
ATOM   2072 H HB2  . LEU A 1 133 ? 83.49171  -30.29148 23.78557 1.000 80.55764  ? 134 LEU A HB2  1 
ATOM   2073 H HB3  . LEU A 1 133 ? 83.26981  -31.72396 23.13429 1.000 80.55764  ? 134 LEU A HB3  1 
ATOM   2074 H HG   . LEU A 1 133 ? 85.76436  -30.99791 24.04136 1.000 76.89723  ? 134 LEU A HG   1 
ATOM   2075 H HD11 . LEU A 1 133 ? 85.27557  -31.99742 26.19658 1.000 83.40660  ? 134 LEU A HD11 1 
ATOM   2076 H HD12 . LEU A 1 133 ? 84.39227  -30.70035 25.94979 1.000 83.40660  ? 134 LEU A HD12 1 
ATOM   2077 H HD13 . LEU A 1 133 ? 83.76076  -32.14293 25.74088 1.000 83.40660  ? 134 LEU A HD13 1 
ATOM   2078 H HD21 . LEU A 1 133 ? 86.10045  -33.29424 24.49871 1.000 76.20038  ? 134 LEU A HD21 1 
ATOM   2079 H HD22 . LEU A 1 133 ? 84.69948  -33.57896 23.80609 1.000 76.20038  ? 134 LEU A HD22 1 
ATOM   2080 H HD23 . LEU A 1 133 ? 85.89593  -32.96952 22.95721 1.000 76.20038  ? 134 LEU A HD23 1 
ATOM   2081 N N    . ASP A 1 134 ? 83.34610  -28.57677 20.74416 1.000 61.07516  ? 135 ASP A N    1 
ATOM   2082 C CA   . ASP A 1 134 ? 82.40335  -28.03136 19.76449 1.000 71.13974  ? 135 ASP A CA   1 
ATOM   2083 C C    . ASP A 1 134 ? 83.07681  -27.80656 18.42332 1.000 64.21583  ? 135 ASP A C    1 
ATOM   2084 O O    . ASP A 1 134 ? 82.62297  -26.96770 17.62726 1.000 68.51445  ? 135 ASP A O    1 
ATOM   2085 C CB   . ASP A 1 134 ? 81.76055  -26.73144 20.23233 1.000 78.27388  ? 135 ASP A CB   1 
ATOM   2086 C CG   . ASP A 1 134 ? 80.85180  -26.94100 21.42954 1.000 89.46353  ? 135 ASP A CG   1 
ATOM   2087 O OD1  . ASP A 1 134 ? 81.18398  -26.40452 22.51052 1.000 88.32447  ? 135 ASP A OD1  1 
ATOM   2088 O OD2  . ASP A 1 134 ? 79.82978  -27.66279 21.30378 1.000 95.03675  ? 135 ASP A OD2  1 
ATOM   2089 H H    . ASP A 1 134 ? 83.96299  -28.02918 20.98745 1.000 73.36146  ? 135 ASP A H    1 
ATOM   2090 H HA   . ASP A 1 134 ? 81.68449  -28.67540 19.66776 1.000 85.43896  ? 135 ASP A HA   1 
ATOM   2091 H HB2  . ASP A 1 134 ? 82.45657  -26.10556 20.48674 1.000 93.99992  ? 135 ASP A HB2  1 
ATOM   2092 H HB3  . ASP A 1 134 ? 81.22911  -26.36111 19.51030 1.000 93.99992  ? 135 ASP A HB3  1 
ATOM   2093 N N    . GLY A 1 135 ? 84.18411  -28.51758 18.18241 1.000 55.98199  ? 136 GLY A N    1 
ATOM   2094 C CA   . GLY A 1 135 ? 84.89614  -28.41981 16.94082 1.000 61.64201  ? 136 GLY A CA   1 
ATOM   2095 C C    . GLY A 1 135 ? 86.11604  -27.54524 17.09211 1.000 56.90882  ? 136 GLY A C    1 
ATOM   2096 O O    . GLY A 1 135 ? 86.38743  -26.98341 18.15704 1.000 57.91843  ? 136 GLY A O    1 
ATOM   2097 H H    . GLY A 1 135 ? 84.53561  -29.06807 18.74187 1.000 67.24965  ? 136 GLY A H    1 
ATOM   2098 H HA2  . GLY A 1 135 ? 85.17797  -29.30270 16.65451 1.000 74.04168  ? 136 GLY A HA2  1 
ATOM   2099 H HA3  . GLY A 1 135 ? 84.31914  -28.03679 16.26166 1.000 74.04168  ? 136 GLY A HA3  1 
ATOM   2100 N N    . PRO A 1 136 ? 86.89070  -27.42641 16.01556 1.000 62.30265  ? 137 PRO A N    1 
ATOM   2101 C CA   . PRO A 1 136 ? 88.12421  -26.63921 16.10459 1.000 58.92427  ? 137 PRO A CA   1 
ATOM   2102 C C    . PRO A 1 136 ? 87.85349  -25.14078 16.11743 1.000 60.55336  ? 137 PRO A C    1 
ATOM   2103 O O    . PRO A 1 136 ? 86.80664  -24.66431 15.67796 1.000 56.33122  ? 137 PRO A O    1 
ATOM   2104 C CB   . PRO A 1 136 ? 88.92050  -27.06945 14.87523 1.000 54.28576  ? 137 PRO A CB   1 
ATOM   2105 C CG   . PRO A 1 136 ? 87.85611  -27.48808 13.87993 1.000 58.03583  ? 137 PRO A CG   1 
ATOM   2106 C CD   . PRO A 1 136 ? 86.74599  -28.11541 14.71237 1.000 59.35824  ? 137 PRO A CD   1 
ATOM   2107 H HA   . PRO A 1 136 ? 88.62084  -26.87492 16.90378 1.000 70.78039  ? 137 PRO A HA   1 
ATOM   2108 H HB2  . PRO A 1 136 ? 89.44334  -26.32527 14.53797 1.000 65.21418  ? 137 PRO A HB2  1 
ATOM   2109 H HB3  . PRO A 1 136 ? 89.50447  -27.81135 15.09765 1.000 65.21418  ? 137 PRO A HB3  1 
ATOM   2110 H HG2  . PRO A 1 136 ? 87.53028  -26.71034 13.40050 1.000 69.71427  ? 137 PRO A HG2  1 
ATOM   2111 H HG3  . PRO A 1 136 ? 88.22506  -28.13220 13.25553 1.000 69.71427  ? 137 PRO A HG3  1 
ATOM   2112 H HD2  . PRO A 1 136 ? 85.87604  -27.93996 14.32081 1.000 71.30116  ? 137 PRO A HD2  1 
ATOM   2113 H HD3  . PRO A 1 136 ? 86.88031  -29.07135 14.80747 1.000 71.30116  ? 137 PRO A HD3  1 
ATOM   2114 N N    . VAL A 1 137 ? 88.79131  -24.42980 16.74137 1.000 57.18997  ? 138 VAL A N    1 
ATOM   2115 C CA   . VAL A 1 137 ? 88.81068  -22.98616 16.92843 1.000 52.95190  ? 138 VAL A CA   1 
ATOM   2116 C C    . VAL A 1 137 ? 90.18773  -22.53612 16.45881 1.000 51.82395  ? 138 VAL A C    1 
ATOM   2117 O O    . VAL A 1 137 ? 91.20204  -23.16318 16.79952 1.000 51.04662  ? 138 VAL A O    1 
ATOM   2118 C CB   . VAL A 1 137 ? 88.56321  -22.60891 18.40268 1.000 55.90877  ? 138 VAL A CB   1 
ATOM   2119 C CG1  . VAL A 1 137 ? 88.98603  -21.13943 18.72018 1.000 51.42471  ? 138 VAL A CG1  1 
ATOM   2120 C CG2  . VAL A 1 137 ? 87.08608  -22.84454 18.79824 1.000 53.55659  ? 138 VAL A CG2  1 
ATOM   2121 H H    . VAL A 1 137 ? 89.48491  -24.79598 17.09410 1.000 68.69923  ? 138 VAL A H    1 
ATOM   2122 H HA   . VAL A 1 137 ? 88.12681  -22.54315 16.40216 1.000 63.61355  ? 138 VAL A HA   1 
ATOM   2123 H HB   . VAL A 1 137 ? 89.12249  -23.18954 18.94210 1.000 67.16179  ? 138 VAL A HB   1 
ATOM   2124 H HG11 . VAL A 1 137 ? 88.76508  -20.93969 19.64332 1.000 61.78092  ? 138 VAL A HG11 1 
ATOM   2125 H HG12 . VAL A 1 137 ? 89.94183  -21.04892 18.58179 1.000 61.78092  ? 138 VAL A HG12 1 
ATOM   2126 H HG13 . VAL A 1 137 ? 88.50767  -20.53823 18.12804 1.000 61.78092  ? 138 VAL A HG13 1 
ATOM   2127 H HG21 . VAL A 1 137 ? 86.95774  -22.56789 19.71905 1.000 64.33917  ? 138 VAL A HG21 1 
ATOM   2128 H HG22 . VAL A 1 137 ? 86.51531  -22.32210 18.21328 1.000 64.33917  ? 138 VAL A HG22 1 
ATOM   2129 H HG23 . VAL A 1 137 ? 86.88070  -23.78791 18.70460 1.000 64.33917  ? 138 VAL A HG23 1 
ATOM   2130 N N    . VAL A 1 138 ? 90.23669  -21.50105 15.62173 1.000 45.51918  ? 139 VAL A N    1 
ATOM   2131 C CA   . VAL A 1 138 ? 91.50677  -21.09071 15.03489 1.000 52.20377  ? 139 VAL A CA   1 
ATOM   2132 C C    . VAL A 1 138 ? 91.91939  -19.71691 15.55985 1.000 47.06118  ? 139 VAL A C    1 
ATOM   2133 O O    . VAL A 1 138 ? 91.11116  -18.77132 15.57440 1.000 45.50211  ? 139 VAL A O    1 
ATOM   2134 C CB   . VAL A 1 138 ? 91.44994  -21.09493 13.49647 1.000 51.31360  ? 139 VAL A CB   1 
ATOM   2135 C CG1  . VAL A 1 138 ? 92.79279  -20.61618 12.93335 1.000 47.99834  ? 139 VAL A CG1  1 
ATOM   2136 C CG2  . VAL A 1 138 ? 91.06208  -22.47401 12.98807 1.000 50.90837  ? 139 VAL A CG2  1 
ATOM   2137 H H    . VAL A 1 138 ? 89.55718  -21.03044 15.38423 1.000 54.69429  ? 139 VAL A H    1 
ATOM   2138 H HA   . VAL A 1 138 ? 92.18300  -21.72117 15.32837 1.000 62.71579  ? 139 VAL A HA   1 
ATOM   2139 H HB   . VAL A 1 138 ? 90.76803  -20.48136 13.18113 1.000 61.64758  ? 139 VAL A HB   1 
ATOM   2140 H HG11 . VAL A 1 138 ? 92.84821  -20.86220 11.99670 1.000 57.66928  ? 139 VAL A HG11 1 
ATOM   2141 H HG12 . VAL A 1 138 ? 92.84846  -19.65222 13.02600 1.000 57.66928  ? 139 VAL A HG12 1 
ATOM   2142 H HG13 . VAL A 1 138 ? 93.51170  -21.03821 13.42929 1.000 57.66928  ? 139 VAL A HG13 1 
ATOM   2143 H HG21 . VAL A 1 138 ? 91.10121  -22.47581 12.01886 1.000 61.16131  ? 139 VAL A HG21 1 
ATOM   2144 H HG22 . VAL A 1 138 ? 91.68261  -23.12835 13.34538 1.000 61.16131  ? 139 VAL A HG22 1 
ATOM   2145 H HG23 . VAL A 1 138 ? 90.16069  -22.67736 13.28310 1.000 61.16131  ? 139 VAL A HG23 1 
ATOM   2146 N N    . TYR A 1 139 ? 93.19343  -19.60772 15.94868 1.000 42.62140  ? 140 TYR A N    1 
ATOM   2147 C CA   . TYR A 1 139 ? 93.82071  -18.36193 16.38814 1.000 46.13606  ? 140 TYR A CA   1 
ATOM   2148 C C    . TYR A 1 139 ? 94.94560  -18.11487 15.39694 1.000 45.89349  ? 140 TYR A C    1 
ATOM   2149 O O    . TYR A 1 139 ? 95.71562  -19.03717 15.09672 1.000 49.71632  ? 140 TYR A O    1 
ATOM   2150 C CB   . TYR A 1 139 ? 94.40594  -18.43664 17.81220 1.000 49.35409  ? 140 TYR A CB   1 
ATOM   2151 C CG   . TYR A 1 139 ? 93.37900  -18.51111 18.92504 1.000 46.14743  ? 140 TYR A CG   1 
ATOM   2152 C CD1  . TYR A 1 139 ? 92.85189  -19.74243 19.33004 1.000 47.67861  ? 140 TYR A CD1  1 
ATOM   2153 C CD2  . TYR A 1 139 ? 92.92234  -17.35930 19.59133 1.000 47.35349  ? 140 TYR A CD2  1 
ATOM   2154 C CE1  . TYR A 1 139 ? 91.89030  -19.82337 20.29525 1.000 49.56396  ? 140 TYR A CE1  1 
ATOM   2155 C CE2  . TYR A 1 139 ? 91.94128  -17.45010 20.58955 1.000 49.46848  ? 140 TYR A CE2  1 
ATOM   2156 C CZ   . TYR A 1 139 ? 91.43068  -18.67818 20.92554 1.000 46.64059  ? 140 TYR A CZ   1 
ATOM   2157 O OH   . TYR A 1 139 ? 90.47065  -18.82442 21.90824 1.000 48.02336  ? 140 TYR A OH   1 
ATOM   2158 H H    . TYR A 1 139 ? 93.73745  -20.27354 15.96648 1.000 51.21694  ? 140 TYR A H    1 
ATOM   2159 H HA   . TYR A 1 139 ? 93.16921  -17.64344 16.40297 1.000 55.43454  ? 140 TYR A HA   1 
ATOM   2160 H HB2  . TYR A 1 139 ? 94.96036  -19.23011 17.87487 1.000 59.29618  ? 140 TYR A HB2  1 
ATOM   2161 H HB3  . TYR A 1 139 ? 94.94317  -17.64361 17.96516 1.000 59.29618  ? 140 TYR A HB3  1 
ATOM   2162 H HD1  . TYR A 1 139 ? 93.16381  -20.52322 18.93259 1.000 57.28560  ? 140 TYR A HD1  1 
ATOM   2163 H HD2  . TYR A 1 139 ? 93.27493  -16.52837 19.36740 1.000 56.89545  ? 140 TYR A HD2  1 
ATOM   2164 H HE1  . TYR A 1 139 ? 91.54133  -20.65244 20.53140 1.000 59.54802  ? 140 TYR A HE1  1 
ATOM   2165 H HE2  . TYR A 1 139 ? 91.63913  -16.68335 21.02050 1.000 59.43345  ? 140 TYR A HE2  1 
ATOM   2166 H HH   . TYR A 1 139 ? 90.23935  -18.07080 22.19834 1.000 57.69930  ? 140 TYR A HH   1 
ATOM   2167 N N    . CYS A 1 140 ? 95.04803  -16.89377 14.87473 1.000 44.87287  ? 141 CYS A N    1 
ATOM   2168 C CA   . CYS A 1 140 ? 96.21422  -16.49256 14.07288 1.000 46.36006  ? 141 CYS A CA   1 
ATOM   2169 C C    . CYS A 1 140 ? 96.62654  -15.06013 14.46888 1.000 47.84486  ? 141 CYS A C    1 
ATOM   2170 O O    . CYS A 1 140 ? 95.79009  -14.21002 14.85441 1.000 44.03701  ? 141 CYS A O    1 
ATOM   2171 C CB   . CYS A 1 140 ? 95.94813  -16.56987 12.57598 1.000 50.22346  ? 141 CYS A CB   1 
ATOM   2172 S SG   . CYS A 1 140 ? 94.59567  -15.50850 11.97510 1.000 51.18702  ? 141 CYS A SG   1 
ATOM   2173 H H    . CYS A 1 140 ? 94.45702  -16.27607 14.96832 1.000 53.91872  ? 141 CYS A H    1 
ATOM   2174 H HA   . CYS A 1 140 ? 96.95379  -17.09032 14.26427 1.000 55.70334  ? 141 CYS A HA   1 
ATOM   2175 H HB2  . CYS A 1 140 ? 96.75508  -16.30519 12.10729 1.000 60.33942  ? 141 CYS A HB2  1 
ATOM   2176 H HB3  . CYS A 1 140 ? 95.71981  -17.48569 12.35229 1.000 60.33942  ? 141 CYS A HB3  1 
ATOM   2177 H HG   . CYS A 1 140 ? 94.45729  -15.68210 10.79582 1.000 61.49569  ? 141 CYS A HG   1 
ATOM   2178 N N    . PHE A 1 141 ? 97.92430  -14.78371 14.37827 1.000 40.88748  ? 142 PHE A N    1 
ATOM   2179 C CA   . PHE A 1 141 ? 98.41637  -13.48397 14.82090 1.000 49.44856  ? 142 PHE A CA   1 
ATOM   2180 C C    . PHE A 1 141 ? 99.71451  -13.20698 14.05877 1.000 50.59243  ? 142 PHE A C    1 
ATOM   2181 O O    . PHE A 1 141 ? 100.38801 -14.12159 13.54409 1.000 50.61661  ? 142 PHE A O    1 
ATOM   2182 C CB   . PHE A 1 141 ? 98.60744  -13.42791 16.39275 1.000 51.15488  ? 142 PHE A CB   1 
ATOM   2183 C CG   . PHE A 1 141 ? 99.70141  -14.35365 16.91874 1.000 48.22498  ? 142 PHE A CG   1 
ATOM   2184 C CD1  . PHE A 1 141 ? 101.03748 -13.95670 16.90563 1.000 48.53446  ? 142 PHE A CD1  1 
ATOM   2185 C CD2  . PHE A 1 141 ? 99.39371  -15.62842 17.39790 1.000 49.31186  ? 142 PHE A CD2  1 
ATOM   2186 C CE1  . PHE A 1 141 ? 102.05717 -14.82795 17.35406 1.000 48.08123  ? 142 PHE A CE1  1 
ATOM   2187 C CE2  . PHE A 1 141 ? 100.39188 -16.49232 17.85465 1.000 46.57969  ? 142 PHE A CE2  1 
ATOM   2188 C CZ   . PHE A 1 141 ? 101.72670 -16.08561 17.82147 1.000 48.87420  ? 142 PHE A CZ   1 
ATOM   2189 H H    . PHE A 1 141 ? 98.52420  -15.31839 14.07194 1.000 49.13625  ? 142 PHE A H    1 
ATOM   2190 H HA   . PHE A 1 141 ? 97.78302  -12.78286 14.60131 1.000 59.40954  ? 142 PHE A HA   1 
ATOM   2191 H HB2  . PHE A 1 141 ? 98.84166  -12.52113 16.64535 1.000 61.45713  ? 142 PHE A HB2  1 
ATOM   2192 H HB3  . PHE A 1 141 ? 97.77390  -13.68559 16.81668 1.000 61.45713  ? 142 PHE A HB3  1 
ATOM   2193 H HD1  . PHE A 1 141 ? 101.26123 -13.10804 16.59805 1.000 58.31262  ? 142 PHE A HD1  1 
ATOM   2194 H HD2  . PHE A 1 141 ? 98.50682  -15.90786 17.41328 1.000 59.24550  ? 142 PHE A HD2  1 
ATOM   2195 H HE1  . PHE A 1 141 ? 102.94620 -14.55567 17.33447 1.000 57.76874  ? 142 PHE A HE1  1 
ATOM   2196 H HE2  . PHE A 1 141 ? 100.16809 -17.33458 18.17934 1.000 55.96689  ? 142 PHE A HE2  1 
ATOM   2197 H HZ   . PHE A 1 141 ? 102.39496 -16.66220 18.11451 1.000 58.72031  ? 142 PHE A HZ   1 
ATOM   2198 N N    . GLY A 1 142 ? 100.06083 -11.92610 14.01905 1.000 51.64962  ? 143 GLY A N    1 
ATOM   2199 C CA   . GLY A 1 142 ? 101.29860 -11.45547 13.42243 1.000 53.36771  ? 143 GLY A CA   1 
ATOM   2200 C C    . GLY A 1 142 ? 101.24854 -9.93797  13.35902 1.000 54.46084  ? 143 GLY A C    1 
ATOM   2201 O O    . GLY A 1 142 ? 100.82766 -9.30735  14.34021 1.000 52.96481  ? 143 GLY A O    1 
ATOM   2202 H H    . GLY A 1 142 ? 99.57937  -11.29074 14.34172 1.000 62.05082  ? 143 GLY A H    1 
ATOM   2203 H HA2  . GLY A 1 142 ? 102.05780 -11.73187 13.95919 1.000 64.11252  ? 143 GLY A HA2  1 
ATOM   2204 H HA3  . GLY A 1 142 ? 101.39824 -11.81350 12.52645 1.000 64.11252  ? 143 GLY A HA3  1 
ATOM   2205 N N    . THR A 1 143 ? 101.58546 -9.33453  12.21282 1.000 54.72554  ? 144 THR A N    1 
ATOM   2206 C CA   . THR A 1 143 ? 101.63119 -7.88769  12.12905 1.000 53.33473  ? 144 THR A CA   1 
ATOM   2207 C C    . THR A 1 143 ? 100.95809 -7.34745  10.88326 1.000 52.41743  ? 144 THR A C    1 
ATOM   2208 O O    . THR A 1 143 ? 100.84814 -8.01977  9.86563  1.000 51.81502  ? 144 THR A O    1 
ATOM   2209 C CB   . THR A 1 143 ? 103.07334 -7.33863  12.11571 1.000 57.43445  ? 144 THR A CB   1 
ATOM   2210 O OG1  . THR A 1 143 ? 103.81229 -8.00192  11.09070 1.000 58.96581  ? 144 THR A OG1  1 
ATOM   2211 C CG2  . THR A 1 143 ? 103.75515 -7.55129  13.45163 1.000 56.40430  ? 144 THR A CG2  1 
ATOM   2212 H H    . THR A 1 143 ? 101.78757 -9.74493  11.48458 1.000 65.74192  ? 144 THR A H    1 
ATOM   2213 H HA   . THR A 1 143 ? 101.14479 -7.57456  12.90768 1.000 64.07294  ? 144 THR A HA   1 
ATOM   2214 H HB   . THR A 1 143 ? 103.05457 -6.38370  11.94643 1.000 68.99260  ? 144 THR A HB   1 
ATOM   2215 H HG1  . THR A 1 143 ? 104.61970 -7.77268  11.12443 1.000 70.83023  ? 144 THR A HG1  1 
ATOM   2216 H HG21 . THR A 1 143 ? 104.63302 -7.13872  13.44547 1.000 67.75642  ? 144 THR A HG21 1 
ATOM   2217 H HG22 . THR A 1 143 ? 103.22586 -7.15458  14.16111 1.000 67.75642  ? 144 THR A HG22 1 
ATOM   2218 H HG23 . THR A 1 143 ? 103.85455 -8.50029  13.62603 1.000 67.75642  ? 144 THR A HG23 1 
ATOM   2219 N N    . LEU A 1 144 ? 100.59857 -6.06795  10.96397 1.000 51.74267  ? 145 LEU A N    1 
ATOM   2220 C CA   . LEU A 1 144 ? 99.95435  -5.33296  9.88958  1.000 53.23266  ? 145 LEU A CA   1 
ATOM   2221 C C    . LEU A 1 144 ? 100.88557 -4.27090  9.31591  1.000 58.90076  ? 145 LEU A C    1 
ATOM   2222 O O    . LEU A 1 144 ? 101.59924 -3.59311  10.05386 1.000 55.81065  ? 145 LEU A O    1 
ATOM   2223 C CB   . LEU A 1 144 ? 98.67865  -4.65108  10.35697 1.000 42.72524  ? 145 LEU A CB   1 
ATOM   2224 C CG   . LEU A 1 144 ? 97.72430  -5.57171  11.11775 1.000 53.42505  ? 145 LEU A CG   1 
ATOM   2225 C CD1  . LEU A 1 144 ? 96.60171  -4.73977  11.76092 1.000 48.23243  ? 145 LEU A CD1  1 
ATOM   2226 C CD2  . LEU A 1 144 ? 97.17073  -6.64013  10.17357 1.000 48.10172  ? 145 LEU A CD2  1 
ATOM   2227 H H    . LEU A 1 144 ? 100.72523 -5.58639  11.66515 1.000 62.16247  ? 145 LEU A H    1 
ATOM   2228 H HA   . LEU A 1 144 ? 99.73696  -5.96785  9.18917  1.000 63.95046  ? 145 LEU A HA   1 
ATOM   2229 H HB2  . LEU A 1 144 ? 98.91655  -3.91894  10.94711 1.000 51.34155  ? 145 LEU A HB2  1 
ATOM   2230 H HB3  . LEU A 1 144 ? 98.20615  -4.31152  9.58087  1.000 51.34155  ? 145 LEU A HB3  1 
ATOM   2231 H HG   . LEU A 1 144 ? 98.19360  -6.03037  11.83209 1.000 64.18133  ? 145 LEU A HG   1 
ATOM   2232 H HD11 . LEU A 1 144 ? 96.00521  -5.33355  12.24311 1.000 57.95018  ? 145 LEU A HD11 1 
ATOM   2233 H HD12 . LEU A 1 144 ? 96.99512  -4.09790  12.37258 1.000 57.95018  ? 145 LEU A HD12 1 
ATOM   2234 H HD13 . LEU A 1 144 ? 96.11336  -4.27543  11.06320 1.000 57.95018  ? 145 LEU A HD13 1 
ATOM   2235 H HD21 . LEU A 1 144 ? 96.55755  -7.20881  10.66500 1.000 57.79334  ? 145 LEU A HD21 1 
ATOM   2236 H HD22 . LEU A 1 144 ? 96.70456  -6.20484  9.44274  1.000 57.79334  ? 145 LEU A HD22 1 
ATOM   2237 H HD23 . LEU A 1 144 ? 97.90719  -7.16852  9.82812  1.000 57.79334  ? 145 LEU A HD23 1 
ATOM   2238 N N    . ARG A 1 145 ? 100.86971 -4.12686  7.98054  1.000 60.14332  ? 146 ARG A N    1 
ATOM   2239 C CA   . ARG A 1 145 ? 101.42407 -2.96635  7.29241  1.000 62.38042  ? 146 ARG A CA   1 
ATOM   2240 C C    . ARG A 1 145 ? 100.28034 -2.29825  6.53625  1.000 57.96884  ? 146 ARG A C    1 
ATOM   2241 O O    . ARG A 1 145 ? 99.31397  -2.96186  6.11730  1.000 57.06981  ? 146 ARG A O    1 
ATOM   2242 C CB   . ARG A 1 145 ? 102.57310 -3.33392  6.36093  1.000 59.04706  ? 146 ARG A CB   1 
ATOM   2243 C CG   . ARG A 1 145 ? 102.13162 -4.05655  5.14780  1.000 69.88633  ? 146 ARG A CG   1 
ATOM   2244 C CD   . ARG A 1 145 ? 103.30706 -4.44862  4.25672  1.000 79.80057  ? 146 ARG A CD   1 
ATOM   2245 N NE   . ARG A 1 145 ? 102.90638 -5.34175  3.17470  1.000 82.34546  ? 146 ARG A NE   1 
ATOM   2246 C CZ   . ARG A 1 145 ? 102.99976 -6.66469  3.23805  1.000 79.34337  ? 146 ARG A CZ   1 
ATOM   2247 N NH1  . ARG A 1 145 ? 103.48294 -7.26837  4.31773  1.000 84.91254  ? 146 ARG A NH1  1 
ATOM   2248 N NH2  . ARG A 1 145 ? 102.62119 -7.39841  2.18512  1.000 83.27883  ? 146 ARG A NH2  1 
ATOM   2249 H H    . ARG A 1 145 ? 100.53234 -4.70817  7.44401  1.000 72.24325  ? 146 ARG A H    1 
ATOM   2250 H HA   . ARG A 1 145 ? 101.80120 -2.33448  7.92441  1.000 74.92777  ? 146 ARG A HA   1 
ATOM   2251 H HB2  . ARG A 1 145 ? 103.02022 -2.52095  6.07799  1.000 70.92774  ? 146 ARG A HB2  1 
ATOM   2252 H HB3  . ARG A 1 145 ? 103.19444 -3.90507  6.83908  1.000 70.92774  ? 146 ARG A HB3  1 
ATOM   2253 H HG2  . ARG A 1 145 ? 101.66694 -4.86666  5.40989  1.000 83.93486  ? 146 ARG A HG2  1 
ATOM   2254 H HG3  . ARG A 1 145 ? 101.53921 -3.48579  4.63382  1.000 83.93486  ? 146 ARG A HG3  1 
ATOM   2255 H HD2  . ARG A 1 145 ? 103.68810 -3.64854  3.86229  1.000 95.83195  ? 146 ARG A HD2  1 
ATOM   2256 H HD3  . ARG A 1 145 ? 103.97463 -4.90447  4.79286  1.000 95.83195  ? 146 ARG A HD3  1 
ATOM   2257 H HE   . ARG A 1 145 ? 102.59187 -4.99137  2.45503  1.000 98.88582  ? 146 ARG A HE   1 
ATOM   2258 H HH11 . ARG A 1 145 ? 103.74199 -6.80135  4.99182  1.000 101.96631 ? 146 ARG A HH11 1 
ATOM   2259 H HH12 . ARG A 1 145 ? 103.53680 -8.12631  4.34283  1.000 101.96631 ? 146 ARG A HH12 1 
ATOM   2260 H HH21 . ARG A 1 145 ? 102.32137 -7.01241  1.47751  1.000 100.00586 ? 146 ARG A HH21 1 
ATOM   2261 H HH22 . ARG A 1 145 ? 102.67768 -8.25599  2.21598  1.000 100.00586 ? 146 ARG A HH22 1 
ATOM   2262 N N    . GLY A 1 146 ? 100.35683 -0.98100  6.39750  1.000 55.42985  ? 147 GLY A N    1 
ATOM   2263 C CA   . GLY A 1 146 ? 99.26238  -0.25846  5.75016  1.000 56.65942  ? 147 GLY A CA   1 
ATOM   2264 C C    . GLY A 1 146 ? 99.56611  1.21871   5.65796  1.000 53.87526  ? 147 GLY A C    1 
ATOM   2265 O O    . GLY A 1 146 ? 100.72505 1.64774   5.72474  1.000 46.05501  ? 147 GLY A O    1 
ATOM   2266 H H    . GLY A 1 146 ? 101.01266 -0.49119  6.66127  1.000 66.58709  ? 147 GLY A H    1 
ATOM   2267 H HA2  . GLY A 1 146 ? 99.12750  -0.60459  4.85411  1.000 68.06258  ? 147 GLY A HA2  1 
ATOM   2268 H HA3  . GLY A 1 146 ? 98.44606  -0.37670  6.26058  1.000 68.06258  ? 147 GLY A HA3  1 
ATOM   2269 N N    . GLU A 1 147 ? 98.49323  1.98940   5.54493  1.000 48.41878  ? 148 GLU A N    1 
ATOM   2270 C CA   . GLU A 1 147 ? 98.62870  3.43551   5.50132  1.000 60.51454  ? 148 GLU A CA   1 
ATOM   2271 C C    . GLU A 1 147 ? 97.49210  4.00759   6.32959  1.000 55.18037  ? 148 GLU A C    1 
ATOM   2272 O O    . GLU A 1 147 ? 96.35102  3.55752   6.18671  1.000 51.78914  ? 148 GLU A O    1 
ATOM   2273 C CB   . GLU A 1 147 ? 98.61339  3.95331   4.03293  1.000 61.61442  ? 148 GLU A CB   1 
ATOM   2274 C CG   . GLU A 1 147 ? 99.97566  3.80129   3.30376  1.000 59.89431  ? 148 GLU A CG   1 
ATOM   2275 C CD   . GLU A 1 147 ? 99.97343  4.38852   1.86112  1.000 64.73122  ? 148 GLU A CD   1 
ATOM   2276 O OE1  . GLU A 1 147 ? 98.99696  5.10228   1.48529  1.000 64.68048  ? 148 GLU A OE1  1 
ATOM   2277 O OE2  . GLU A 1 147 ? 100.96086 4.14614   1.12070  1.000 62.83430  ? 148 GLU A OE2  1 
ATOM   2278 H H    . GLU A 1 147 ? 97.68503  1.70016   5.49242  1.000 58.17380  ? 148 GLU A H    1 
ATOM   2279 H HA   . GLU A 1 147 ? 99.46759  3.73402   5.88608  1.000 72.68871  ? 148 GLU A HA   1 
ATOM   2280 H HB2  . GLU A 1 147 ? 97.95140  3.45158   3.53198  1.000 74.00856  ? 148 GLU A HB2  1 
ATOM   2281 H HB3  . GLU A 1 147 ? 98.38265  4.89545   4.03664  1.000 74.00856  ? 148 GLU A HB3  1 
ATOM   2282 H HG2  . GLU A 1 147 ? 100.65770 4.26645   3.81303  1.000 71.94444  ? 148 GLU A HG2  1 
ATOM   2283 H HG3  . GLU A 1 147 ? 100.19414 2.85833   3.24056  1.000 71.94444  ? 148 GLU A HG3  1 
ATOM   2284 N N    . TRP A 1 148 ? 97.79173  4.97551   7.21120  1.000 58.49375  ? 149 TRP A N    1 
ATOM   2285 C CA   . TRP A 1 148 ? 96.72300  5.74865   7.86920  1.000 66.48666  ? 149 TRP A CA   1 
ATOM   2286 C C    . TRP A 1 148 ? 95.97950  6.51636   6.78042  1.000 66.79635  ? 149 TRP A C    1 
ATOM   2287 O O    . TRP A 1 148 ? 96.45184  6.65143   5.65681  1.000 64.51642  ? 149 TRP A O    1 
ATOM   2288 C CB   . TRP A 1 148 ? 97.30458  6.68217   8.93812  1.000 59.45667  ? 149 TRP A CB   1 
ATOM   2289 C CG   . TRP A 1 148 ? 98.15260  5.95910   9.92966  1.000 58.39009  ? 149 TRP A CG   1 
ATOM   2290 C CD1  . TRP A 1 148 ? 99.51138  6.03968   10.06536 1.000 57.46987  ? 149 TRP A CD1  1 
ATOM   2291 C CD2  . TRP A 1 148 ? 97.70797  5.00165   10.90508 1.000 52.79426  ? 149 TRP A CD2  1 
ATOM   2292 N NE1  . TRP A 1 148 ? 99.93809  5.20498   11.08916 1.000 53.28480  ? 149 TRP A NE1  1 
ATOM   2293 C CE2  . TRP A 1 148 ? 98.84816  4.55016   11.60273 1.000 47.91213  ? 149 TRP A CE2  1 
ATOM   2294 C CE3  . TRP A 1 148 ? 96.46252  4.47549   11.24332 1.000 53.68483  ? 149 TRP A CE3  1 
ATOM   2295 C CZ2  . TRP A 1 148 ? 98.77670  3.58810   12.58626 1.000 49.69085  ? 149 TRP A CZ2  1 
ATOM   2296 C CZ3  . TRP A 1 148 ? 96.39724  3.52365   12.26063 1.000 52.30134  ? 149 TRP A CZ3  1 
ATOM   2297 C CH2  . TRP A 1 148 ? 97.54455  3.08425   12.89658 1.000 50.01939  ? 149 TRP A CH2  1 
ATOM   2298 H H    . TRP A 1 148 ? 98.58968  5.19940   7.44086  1.000 70.26376  ? 149 TRP A H    1 
ATOM   2299 H HA   . TRP A 1 148 ? 96.10126  5.16628   8.33307  1.000 79.85526  ? 149 TRP A HA   1 
ATOM   2300 H HB2  . TRP A 1 148 ? 97.85387  7.35481   8.50598  1.000 71.41927  ? 149 TRP A HB2  1 
ATOM   2301 H HB3  . TRP A 1 148 ? 96.57619  7.10673   9.41781  1.000 71.41927  ? 149 TRP A HB3  1 
ATOM   2302 H HD1  . TRP A 1 148 ? 100.06791 6.57534   9.54745  1.000 69.03511  ? 149 TRP A HD1  1 
ATOM   2303 H HE1  . TRP A 1 148 ? 100.75032 5.11377   11.35668 1.000 64.01303  ? 149 TRP A HE1  1 
ATOM   2304 H HE3  . TRP A 1 148 ? 95.69285  4.75265   10.80095 1.000 64.49306  ? 149 TRP A HE3  1 
ATOM   2305 H HZ2  . TRP A 1 148 ? 99.54140  3.29133   13.02451 1.000 59.70029  ? 149 TRP A HZ2  1 
ATOM   2306 H HZ3  . TRP A 1 148 ? 95.57141  3.17975   12.51486 1.000 62.83288  ? 149 TRP A HZ3  1 
ATOM   2307 H HH2  . TRP A 1 148 ? 97.47567  2.42869   13.55262 1.000 60.09454  ? 149 TRP A HH2  1 
ATOM   2308 N N    . PRO A 1 149 ? 94.80306  7.04104   7.09686  1.000 70.74800  ? 150 PRO A N    1 
ATOM   2309 C CA   . PRO A 1 149 ? 93.99546  7.69877   6.05535  1.000 73.11210  ? 150 PRO A CA   1 
ATOM   2310 C C    . PRO A 1 149 ? 94.67968  8.86965   5.36042  1.000 74.84413  ? 150 PRO A C    1 
ATOM   2311 O O    . PRO A 1 149 ? 94.31785  9.19042   4.22365  1.000 79.52925  ? 150 PRO A O    1 
ATOM   2312 C CB   . PRO A 1 149 ? 92.73319  8.14772   6.80635  1.000 72.41610  ? 150 PRO A CB   1 
ATOM   2313 C CG   . PRO A 1 149 ? 92.65984  7.18788   8.01945  1.000 70.66444  ? 150 PRO A CG   1 
ATOM   2314 C CD   . PRO A 1 149 ? 94.10326  6.96485   8.39769  1.000 70.18557  ? 150 PRO A CD   1 
ATOM   2315 H HA   . PRO A 1 149 ? 93.75230  7.04255   5.38368  1.000 87.80579  ? 150 PRO A HA   1 
ATOM   2316 H HB2  . PRO A 1 149 ? 92.82492  9.06974   7.09333  1.000 86.97059  ? 150 PRO A HB2  1 
ATOM   2317 H HB3  . PRO A 1 149 ? 91.95380  8.05357   6.23663  1.000 86.97059  ? 150 PRO A HB3  1 
ATOM   2318 H HG2  . PRO A 1 149 ? 92.16784  7.60293   8.74509  1.000 84.86860  ? 150 PRO A HG2  1 
ATOM   2319 H HG3  . PRO A 1 149 ? 92.23269  6.35583   7.76227  1.000 84.86860  ? 150 PRO A HG3  1 
ATOM   2320 H HD2  . PRO A 1 149 ? 94.41478  7.65861   8.99982  1.000 84.29395  ? 150 PRO A HD2  1 
ATOM   2321 H HD3  . PRO A 1 149 ? 94.22383  6.09300   8.80540  1.000 84.29395  ? 150 PRO A HD3  1 
ATOM   2322 N N    . ASP A 1 150 ? 95.65959  9.50098   5.97360  1.000 71.72394  ? 151 ASP A N    1 
ATOM   2323 C CA   . ASP A 1 150 ? 96.39298  10.56280  5.30129  1.000 73.46920  ? 151 ASP A CA   1 
ATOM   2324 C C    . ASP A 1 150 ? 97.52541  10.04554  4.40526  1.000 72.27937  ? 151 ASP A C    1 
ATOM   2325 O O    . ASP A 1 150 ? 98.38469  10.83125  3.99386  1.000 64.60378  ? 151 ASP A O    1 
ATOM   2326 C CB   . ASP A 1 150 ? 96.93711  11.53813  6.35746  1.000 73.86932  ? 151 ASP A CB   1 
ATOM   2327 C CG   . ASP A 1 150 ? 98.08597  10.96018  7.18303  1.000 70.95109  ? 151 ASP A CG   1 
ATOM   2328 O OD1  . ASP A 1 150 ? 98.43242  9.77313   7.04005  1.000 73.95329  ? 151 ASP A OD1  1 
ATOM   2329 O OD2  . ASP A 1 150 ? 98.66949  11.71440  7.98610  1.000 73.96795  ? 151 ASP A OD2  1 
ATOM   2330 H H    . ASP A 1 150 ? 95.92080  9.33628   6.77625  1.000 86.14000  ? 151 ASP A H    1 
ATOM   2331 H HA   . ASP A 1 150 ? 95.78791  11.05114  4.72136  1.000 88.23431  ? 151 ASP A HA   1 
ATOM   2332 H HB2  . ASP A 1 150 ? 97.26384  12.33442  5.91017  1.000 88.71445  ? 151 ASP A HB2  1 
ATOM   2333 H HB3  . ASP A 1 150 ? 96.22028  11.77109  6.96802  1.000 88.71445  ? 151 ASP A HB3  1 
ATOM   2334 N N    . GLY A 1 151 ? 97.56410  8.75177   4.11150  1.000 71.94561  ? 152 GLY A N    1 
ATOM   2335 C CA   . GLY A 1 151 ? 98.66032  8.20397   3.33955  1.000 76.01208  ? 152 GLY A CA   1 
ATOM   2336 C C    . GLY A 1 151 ? 99.92893  7.92345   4.10668  1.000 65.83378  ? 152 GLY A C    1 
ATOM   2337 O O    . GLY A 1 151 ? 100.93544 7.53227   3.49828  1.000 65.65355  ? 152 GLY A O    1 
ATOM   2338 H H    . GLY A 1 151 ? 96.96944  8.17725   4.34795  1.000 86.40600  ? 152 GLY A H    1 
ATOM   2339 H HA2  . GLY A 1 151 ? 98.36855  7.36826   2.94285  1.000 91.28577  ? 152 GLY A HA2  1 
ATOM   2340 H HA3  . GLY A 1 151 ? 98.87986  8.82985   2.63176  1.000 91.28577  ? 152 GLY A HA3  1 
ATOM   2341 N N    . THR A 1 152 ? 99.91471  8.06534   5.41896  1.000 66.66426  ? 153 THR A N    1 
ATOM   2342 C CA   . THR A 1 152 ? 101.16298 7.80572   6.14103  1.000 63.55344  ? 153 THR A CA   1 
ATOM   2343 C C    . THR A 1 152 ? 101.34122 6.30310   6.36489  1.000 61.43056  ? 153 THR A C    1 
ATOM   2344 O O    . THR A 1 152 ? 100.41754 5.63285   6.83894  1.000 57.79229  ? 153 THR A O    1 
ATOM   2345 C CB   . THR A 1 152 ? 101.19734 8.52524   7.47950  1.000 68.58379  ? 153 THR A CB   1 
ATOM   2346 O OG1  . THR A 1 152 ? 100.91753 9.92091   7.32124  1.000 60.74122  ? 153 THR A OG1  1 
ATOM   2347 C CG2  . THR A 1 152 ? 102.57680 8.32300   8.09267  1.000 65.21968  ? 153 THR A CG2  1 
ATOM   2348 H H    . THR A 1 152 ? 99.23768  8.29753   5.89573  1.000 80.06838  ? 153 THR A H    1 
ATOM   2349 H HA   . THR A 1 152 ? 101.90156 8.13600   5.60595  1.000 76.33539  ? 153 THR A HA   1 
ATOM   2350 H HB   . THR A 1 152 ? 100.51941 8.16805   8.07425  1.000 82.37181  ? 153 THR A HB   1 
ATOM   2351 H HG1  . THR A 1 152 ? 100.26053 10.02587  6.80847  1.000 72.96073  ? 153 THR A HG1  1 
ATOM   2352 H HG21 . THR A 1 152 ? 102.69929 8.92816   8.84078  1.000 78.33489  ? 153 THR A HG21 1 
ATOM   2353 H HG22 . THR A 1 152 ? 102.66925 7.41025   8.40771  1.000 78.33489  ? 153 THR A HG22 1 
ATOM   2354 H HG23 . THR A 1 152 ? 103.26329 8.49842   7.43020  1.000 78.33489  ? 153 THR A HG23 1 
ATOM   2355 N N    . PRO A 1 153 ? 102.47783 5.73360   5.99375  1.000 67.90656  ? 154 PRO A N    1 
ATOM   2356 C CA   . PRO A 1 153 ? 102.62088 4.28010   6.09819  1.000 70.09758  ? 154 PRO A CA   1 
ATOM   2357 C C    . PRO A 1 153 ? 102.99362 3.86139   7.50320  1.000 69.74647  ? 154 PRO A C    1 
ATOM   2358 O O    . PRO A 1 153 ? 103.70567 4.56336   8.22833  1.000 64.24773  ? 154 PRO A O    1 
ATOM   2359 C CB   . PRO A 1 153 ? 103.74728 3.95129   5.10644  1.000 70.15480  ? 154 PRO A CB   1 
ATOM   2360 C CG   . PRO A 1 153 ? 104.57371 5.16777   5.09459  1.000 69.50965  ? 154 PRO A CG   1 
ATOM   2361 C CD   . PRO A 1 153 ? 103.57488 6.32500   5.19357  1.000 74.55343  ? 154 PRO A CD   1 
ATOM   2362 H HA   . PRO A 1 153 ? 101.80841 3.82920   5.81983  1.000 84.18837  ? 154 PRO A HA   1 
ATOM   2363 H HB2  . PRO A 1 153 ? 104.25436 3.18531   5.41797  1.000 84.25702  ? 154 PRO A HB2  1 
ATOM   2364 H HB3  . PRO A 1 153 ? 103.37746 3.76946   4.22833  1.000 84.25702  ? 154 PRO A HB3  1 
ATOM   2365 H HG2  . PRO A 1 153 ? 105.17756 5.16490   5.85371  1.000 83.48285  ? 154 PRO A HG2  1 
ATOM   2366 H HG3  . PRO A 1 153 ? 105.07965 5.21598   4.26839  1.000 83.48285  ? 154 PRO A HG3  1 
ATOM   2367 H HD2  . PRO A 1 153 ? 103.96744 7.08588   5.64947  1.000 89.53538  ? 154 PRO A HD2  1 
ATOM   2368 H HD3  . PRO A 1 153 ? 103.26114 6.59039   4.31492  1.000 89.53538  ? 154 PRO A HD3  1 
ATOM   2369 N N    . PHE A 1 154 ? 102.47758 2.69928   7.87161  1.000 64.99832  ? 155 PHE A N    1 
ATOM   2370 C CA   . PHE A 1 154 ? 102.88337 2.00120   9.06227  1.000 63.92653  ? 155 PHE A CA   1 
ATOM   2371 C C    . PHE A 1 154 ? 103.15533 0.55042   8.71956  1.000 63.60722  ? 155 PHE A C    1 
ATOM   2372 O O    . PHE A 1 154 ? 102.62153 -0.00079  7.74199  1.000 62.27934  ? 155 PHE A O    1 
ATOM   2373 C CB   . PHE A 1 154 ? 101.81360 2.10516   10.13362 1.000 54.94968  ? 155 PHE A CB   1 
ATOM   2374 C CG   . PHE A 1 154 ? 100.50326 1.53024   9.74571  1.000 51.63138  ? 155 PHE A CG   1 
ATOM   2375 C CD1  . PHE A 1 154 ? 100.24845 0.17300   9.90261  1.000 54.70668  ? 155 PHE A CD1  1 
ATOM   2376 C CD2  . PHE A 1 154 ? 99.49788  2.33958   9.28218  1.000 53.06411  ? 155 PHE A CD2  1 
ATOM   2377 C CE1  . PHE A 1 154 ? 99.00994  -0.37436  9.59309  1.000 48.31785  ? 155 PHE A CE1  1 
ATOM   2378 C CE2  . PHE A 1 154 ? 98.23682  1.81142   8.96042  1.000 54.13979  ? 155 PHE A CE2  1 
ATOM   2379 C CZ   . PHE A 1 154 ? 97.99378  0.44473   9.11553  1.000 49.88449  ? 155 PHE A CZ   1 
ATOM   2380 H H    . PHE A 1 154 ? 101.86870 2.28580   7.42675  1.000 78.06925  ? 155 PHE A H    1 
ATOM   2381 H HA   . PHE A 1 154 ? 103.70417 2.38015   9.41381  1.000 76.78311  ? 155 PHE A HA   1 
ATOM   2382 H HB2  . PHE A 1 154 ? 102.11940 1.63250   10.92355 1.000 66.01088  ? 155 PHE A HB2  1 
ATOM   2383 H HB3  . PHE A 1 154 ? 101.67325 3.04222   10.34127 1.000 66.01088  ? 155 PHE A HB3  1 
ATOM   2384 H HD1  . PHE A 1 154 ? 100.92298 -0.38169  10.22232 1.000 65.71928  ? 155 PHE A HD1  1 
ATOM   2385 H HD2  . PHE A 1 154 ? 99.65322  3.25075   9.17947  1.000 63.74820  ? 155 PHE A HD2  1 
ATOM   2386 H HE1  . PHE A 1 154 ? 98.86123  -1.28555  9.70499  1.000 58.05268  ? 155 PHE A HE1  1 
ATOM   2387 H HE2  . PHE A 1 154 ? 97.56450  2.37096   8.64450  1.000 65.03901  ? 155 PHE A HE2  1 
ATOM   2388 H HZ   . PHE A 1 154 ? 97.16223  0.08726   8.90188  1.000 59.93266  ? 155 PHE A HZ   1 
ATOM   2389 N N    . ASP A 1 155 ? 103.98509 -0.06577  9.55965  1.000 56.57760  ? 156 ASP A N    1 
ATOM   2390 C CA   . ASP A 1 155 ? 104.22740 -1.48926  9.48086  1.000 61.57312  ? 156 ASP A CA   1 
ATOM   2391 C C    . ASP A 1 155 ? 104.38048 -2.03262  10.89958 1.000 69.02434  ? 156 ASP A C    1 
ATOM   2392 O O    . ASP A 1 155 ? 104.59082 -1.29526  11.87888 1.000 60.32992  ? 156 ASP A O    1 
ATOM   2393 C CB   . ASP A 1 155 ? 105.46278 -1.80839  8.62331  1.000 61.67488  ? 156 ASP A CB   1 
ATOM   2394 C CG   . ASP A 1 155 ? 106.74572 -1.38551  9.27851  1.000 71.16213  ? 156 ASP A CG   1 
ATOM   2395 O OD1  . ASP A 1 155 ? 106.69230 -0.78564  10.35837 1.000 82.58914  ? 156 ASP A OD1  1 
ATOM   2396 O OD2  . ASP A 1 155 ? 107.82644 -1.66469  8.73746  1.000 71.98698  ? 156 ASP A OD2  1 
ATOM   2397 H H    . ASP A 1 155 ? 104.42010 0.32966   10.18735 1.000 67.96439  ? 156 ASP A H    1 
ATOM   2398 H HA   . ASP A 1 155 ? 103.47078 -1.93597  9.06992  1.000 73.95901  ? 156 ASP A HA   1 
ATOM   2399 H HB2  . ASP A 1 155 ? 105.50415 -2.76555  8.47157  1.000 74.08112  ? 156 ASP A HB2  1 
ATOM   2400 H HB3  . ASP A 1 155 ? 105.38962 -1.34109  7.77645  1.000 74.08112  ? 156 ASP A HB3  1 
ATOM   2401 N N    . ASN A 1 156 ? 104.22771 -3.34686  11.02504 1.000 71.21456  ? 157 ASN A N    1 
ATOM   2402 C CA   . ASN A 1 156 ? 104.63049 -4.00956  12.26286 1.000 64.47928  ? 157 ASN A CA   1 
ATOM   2403 C C    . ASN A 1 156 ? 103.63983 -3.76747  13.41524 1.000 54.66022  ? 157 ASN A C    1 
ATOM   2404 O O    . ASN A 1 156 ? 103.98673 -3.84299  14.59522 1.000 51.50104  ? 157 ASN A O    1 
ATOM   2405 C CB   . ASN A 1 156 ? 106.02516 -3.53109  12.62770 1.000 70.18260  ? 157 ASN A CB   1 
ATOM   2406 C CG   . ASN A 1 156 ? 106.85206 -4.60432  13.19814 1.000 77.30305  ? 157 ASN A CG   1 
ATOM   2407 O OD1  . ASN A 1 156 ? 107.29841 -5.49818  12.47568 1.000 82.69105  ? 157 ASN A OD1  1 
ATOM   2408 N ND2  . ASN A 1 156 ? 107.07390 -4.55102  14.50566 1.000 92.00509  ? 157 ASN A ND2  1 
ATOM   2409 H H    . ASN A 1 156 ? 103.90069 -3.86471  10.42131 1.000 85.52873  ? 157 ASN A H    1 
ATOM   2410 H HA   . ASN A 1 156 ? 104.63922 -4.97123  12.13630 1.000 77.44640  ? 157 ASN A HA   1 
ATOM   2411 H HB2  . ASN A 1 156 ? 106.46700 -3.20152  11.82954 1.000 84.29038  ? 157 ASN A HB2  1 
ATOM   2412 H HB3  . ASN A 1 156 ? 105.95578 -2.82155  13.28545 1.000 84.29038  ? 157 ASN A HB3  1 
ATOM   2413 H HD21 . ASN A 1 156 ? 106.73963 -3.91096  14.97278 1.000 110.47737 ? 157 ASN A HD21 1 
ATOM   2414 H HD22 . ASN A 1 156 ? 107.55190 -5.15654  14.88574 1.000 110.47737 ? 157 ASN A HD22 1 
ATOM   2415 N N    . VAL A 1 157 ? 102.37508 -3.54856  13.08879 1.000 49.69214  ? 158 VAL A N    1 
ATOM   2416 C CA   . VAL A 1 157 ? 101.33064 -3.32250  14.08100 1.000 50.55164  ? 158 VAL A CA   1 
ATOM   2417 C C    . VAL A 1 157 ? 100.73323 -4.68645  14.42470 1.000 54.85824  ? 158 VAL A C    1 
ATOM   2418 O O    . VAL A 1 157 ? 100.02585 -5.28170  13.61927 1.000 54.54442  ? 158 VAL A O    1 
ATOM   2419 C CB   . VAL A 1 157 ? 100.25354 -2.37433  13.53553 1.000 52.51437  ? 158 VAL A CB   1 
ATOM   2420 C CG1  . VAL A 1 157 ? 99.14174  -2.15526  14.52065 1.000 51.53011  ? 158 VAL A CG1  1 
ATOM   2421 C CG2  . VAL A 1 157 ? 100.89174 -1.05750  13.09321 1.000 50.76222  ? 158 VAL A CG2  1 
ATOM   2422 H H    . VAL A 1 157 ? 102.08745 -3.52518  12.27865 1.000 59.70184  ? 158 VAL A H    1 
ATOM   2423 H HA   . VAL A 1 157 ? 101.71274 -2.93357  14.88327 1.000 60.73324  ? 158 VAL A HA   1 
ATOM   2424 H HB   . VAL A 1 157 ? 99.84292  -2.78708  12.75969 1.000 63.08851  ? 158 VAL A HB   1 
ATOM   2425 H HG11 . VAL A 1 157 ? 98.81727  -1.24530  14.43345 1.000 61.90740  ? 158 VAL A HG11 1 
ATOM   2426 H HG12 . VAL A 1 157 ? 98.42518  -2.78140  14.33252 1.000 61.90740  ? 158 VAL A HG12 1 
ATOM   2427 H HG13 . VAL A 1 157 ? 99.48125  -2.30085  15.41755 1.000 61.90740  ? 158 VAL A HG13 1 
ATOM   2428 H HG21 . VAL A 1 157 ? 100.19618 -0.46012  12.77662 1.000 60.98593  ? 158 VAL A HG21 1 
ATOM   2429 H HG22 . VAL A 1 157 ? 101.35080 -0.65940  13.84930 1.000 60.98593  ? 158 VAL A HG22 1 
ATOM   2430 H HG23 . VAL A 1 157 ? 101.52376 -1.23690  12.37958 1.000 60.98593  ? 158 VAL A HG23 1 
ATOM   2431 N N    . ARG A 1 158 ? 100.93575 -5.14707  15.64683 1.000 52.63355  ? 159 ARG A N    1 
ATOM   2432 C CA   . ARG A 1 158 ? 100.46713 -6.45918  16.07854 1.000 49.56187  ? 159 ARG A CA   1 
ATOM   2433 C C    . ARG A 1 158 ? 98.96244  -6.62829  15.92089 1.000 48.68284  ? 159 ARG A C    1 
ATOM   2434 O O    . ARG A 1 158 ? 98.17418  -5.68462  16.09759 1.000 47.27181  ? 159 ARG A O    1 
ATOM   2435 C CB   . ARG A 1 158 ? 100.85294 -6.66455  17.53005 1.000 48.47481  ? 159 ARG A CB   1 
ATOM   2436 C CG   . ARG A 1 158 ? 102.35017 -6.60617  17.76323 1.000 49.68902  ? 159 ARG A CG   1 
ATOM   2437 C CD   . ARG A 1 158 ? 102.71206 -6.54329  19.22990 1.000 51.67887  ? 159 ARG A CD   1 
ATOM   2438 N NE   . ARG A 1 158 ? 102.33100 -7.72975  19.98450 1.000 52.13779  ? 159 ARG A NE   1 
ATOM   2439 C CZ   . ARG A 1 158 ? 101.36091 -7.76531  20.88656 1.000 55.15917  ? 159 ARG A CZ   1 
ATOM   2440 N NH1  . ARG A 1 158 ? 100.59511 -6.70202  21.14531 1.000 47.14949  ? 159 ARG A NH1  1 
ATOM   2441 N NH2  . ARG A 1 158 ? 101.13520 -8.90160  21.52833 1.000 53.41561  ? 159 ARG A NH2  1 
ATOM   2442 H H    . ARG A 1 158 ? 101.35073 -4.71322  16.26259 1.000 63.23153  ? 159 ARG A H    1 
ATOM   2443 H HA   . ARG A 1 158 ? 100.88097 -7.13703  15.52162 1.000 59.54551  ? 159 ARG A HA   1 
ATOM   2444 H HB2  . ARG A 1 158 ? 100.43984 -5.96970  18.06618 1.000 58.24104  ? 159 ARG A HB2  1 
ATOM   2445 H HB3  . ARG A 1 158 ? 100.53957 -7.53619  17.81804 1.000 58.24104  ? 159 ARG A HB3  1 
ATOM   2446 H HG2  . ARG A 1 158 ? 102.76017 -7.40089  17.38744 1.000 59.69809  ? 159 ARG A HG2  1 
ATOM   2447 H HG3  . ARG A 1 158 ? 102.70682 -5.81358  17.33254 1.000 59.69809  ? 159 ARG A HG3  1 
ATOM   2448 H HD2  . ARG A 1 158 ? 103.67319 -6.43951  19.30960 1.000 62.08591  ? 159 ARG A HD2  1 
ATOM   2449 H HD3  . ARG A 1 158 ? 102.26196 -5.78269  19.62965 1.000 62.08591  ? 159 ARG A HD3  1 
ATOM   2450 H HE   . ARG A 1 158 ? 102.76526 -8.45669  19.83429 1.000 62.63661  ? 159 ARG A HE   1 
ATOM   2451 H HH11 . ARG A 1 158 ? 100.72458 -5.96534  20.72089 1.000 56.65066  ? 159 ARG A HH11 1 
ATOM   2452 H HH12 . ARG A 1 158 ? 99.97256  -6.75408  21.73635 1.000 56.65066  ? 159 ARG A HH12 1 
ATOM   2453 H HH21 . ARG A 1 158 ? 101.61350 -9.59520  21.35585 1.000 64.17000  ? 159 ARG A HH21 1 
ATOM   2454 H HH22 . ARG A 1 158 ? 100.51033 -8.94587  22.11755 1.000 64.17000  ? 159 ARG A HH22 1 
ATOM   2455 N N    . PHE A 1 159 ? 98.57070  -7.85211  15.54852 1.000 44.16324  ? 160 PHE A N    1 
ATOM   2456 C CA   . PHE A 1 159 ? 97.14824  -8.17272  15.43384 1.000 48.88552  ? 160 PHE A CA   1 
ATOM   2457 C C    . PHE A 1 159 ? 96.94845  -9.61679  15.87789 1.000 46.99246  ? 160 PHE A C    1 
ATOM   2458 O O    . PHE A 1 159 ? 97.90195  -10.41115 15.90666 1.000 42.86441  ? 160 PHE A O    1 
ATOM   2459 C CB   . PHE A 1 159 ? 96.61437  -7.97259  13.98714 1.000 53.41498  ? 160 PHE A CB   1 
ATOM   2460 C CG   . PHE A 1 159 ? 96.96494  -9.12632  13.03588 1.000 48.64115  ? 160 PHE A CG   1 
ATOM   2461 C CD1  . PHE A 1 159 ? 98.20129  -9.14973  12.37010 1.000 49.84667  ? 160 PHE A CD1  1 
ATOM   2462 C CD2  . PHE A 1 159 ? 96.05419  -10.19167 12.82442 1.000 48.27341  ? 160 PHE A CD2  1 
ATOM   2463 C CE1  . PHE A 1 159 ? 98.54379  -10.21883 11.53956 1.000 51.35467  ? 160 PHE A CE1  1 
ATOM   2464 C CE2  . PHE A 1 159 ? 96.40408  -11.27028 12.02761 1.000 49.95910  ? 160 PHE A CE2  1 
ATOM   2465 C CZ   . PHE A 1 159 ? 97.63532  -11.28600 11.38477 1.000 49.38796  ? 160 PHE A CZ   1 
ATOM   2466 H H    . PHE A 1 159 ? 99.10237  -8.50141  15.36055 1.000 53.06716  ? 160 PHE A H    1 
ATOM   2467 H HA   . PHE A 1 159 ? 96.63947  -7.58816  16.01724 1.000 58.73389  ? 160 PHE A HA   1 
ATOM   2468 H HB2  . PHE A 1 159 ? 95.64779  -7.89750  14.01855 1.000 64.16924  ? 160 PHE A HB2  1 
ATOM   2469 H HB3  . PHE A 1 159 ? 96.99856  -7.16017  13.62209 1.000 64.16924  ? 160 PHE A HB3  1 
ATOM   2470 H HD1  . PHE A 1 159 ? 98.79828  -8.44572  12.48354 1.000 59.88727  ? 160 PHE A HD1  1 
ATOM   2471 H HD2  . PHE A 1 159 ? 95.21467  -10.16664 13.22378 1.000 57.99935  ? 160 PHE A HD2  1 
ATOM   2472 H HE1  . PHE A 1 159 ? 99.36029  -10.22685 11.09442 1.000 61.69687  ? 160 PHE A HE1  1 
ATOM   2473 H HE2  . PHE A 1 159 ? 95.81531  -11.98260 11.92345 1.000 60.02219  ? 160 PHE A HE2  1 
ATOM   2474 H HZ   . PHE A 1 159 ? 97.86316  -12.00893 10.84592 1.000 59.33681  ? 160 PHE A HZ   1 
ATOM   2475 N N    . ILE A 1 160 ? 95.68968  -9.95704  16.18918 1.000 41.70955  ? 161 ILE A N    1 
ATOM   2476 C CA   . ILE A 1 160 ? 95.29335  -11.34658 16.41634 1.000 41.22138  ? 161 ILE A CA   1 
ATOM   2477 C C    . ILE A 1 160 ? 93.83053  -11.53369 16.02592 1.000 44.70553  ? 161 ILE A C    1 
ATOM   2478 O O    . ILE A 1 160 ? 92.97835  -10.68516 16.31907 1.000 44.91893  ? 161 ILE A O    1 
ATOM   2479 C CB   . ILE A 1 160 ? 95.58325  -11.77296 17.86558 1.000 51.02201  ? 161 ILE A CB   1 
ATOM   2480 C CG1  . ILE A 1 160 ? 95.04920  -13.19759 18.10894 1.000 49.06654  ? 161 ILE A CG1  1 
ATOM   2481 C CG2  . ILE A 1 160 ? 94.96409  -10.83602 18.95254 1.000 46.07331  ? 161 ILE A CG2  1 
ATOM   2482 C CD1  . ILE A 1 160 ? 95.69118  -13.90308 19.29769 1.000 49.12271  ? 161 ILE A CD1  1 
ATOM   2483 H H    . ILE A 1 160 ? 95.04530  -9.39390  16.27428 1.000 50.12272  ? 161 ILE A H    1 
ATOM   2484 H HA   . ILE A 1 160 ? 95.80460  -11.92332 15.82735 1.000 49.53692  ? 161 ILE A HA   1 
ATOM   2485 H HB   . ILE A 1 160 ? 96.54792  -11.72334 17.95426 1.000 61.29768  ? 161 ILE A HB   1 
ATOM   2486 H HG12 . ILE A 1 160 ? 94.09479  -13.14816 18.27492 1.000 58.95111  ? 161 ILE A HG12 1 
ATOM   2487 H HG13 . ILE A 1 160 ? 95.22125  -13.73371 17.31908 1.000 58.95111  ? 161 ILE A HG13 1 
ATOM   2488 H HG21 . ILE A 1 160 ? 95.27568  -11.11767 19.82689 1.000 55.35923  ? 161 ILE A HG21 1 
ATOM   2489 H HG22 . ILE A 1 160 ? 95.24420  -9.92357  18.77967 1.000 55.35923  ? 161 ILE A HG22 1 
ATOM   2490 H HG23 . ILE A 1 160 ? 93.99707  -10.89886 18.90995 1.000 55.35923  ? 161 ILE A HG23 1 
ATOM   2491 H HD11 . ILE A 1 160 ? 95.34234  -14.80638 19.35489 1.000 59.01852  ? 161 ILE A HD11 1 
ATOM   2492 H HD12 . ILE A 1 160 ? 96.65233  -13.92719 19.16922 1.000 59.01852  ? 161 ILE A HD12 1 
ATOM   2493 H HD13 . ILE A 1 160 ? 95.47791  -13.41421 20.10789 1.000 59.01852  ? 161 ILE A HD13 1 
ATOM   2494 N N    . ASP A 1 161 ? 93.54643  -12.65600 15.34063 1.000 41.24755  ? 162 ASP A N    1 
ATOM   2495 C CA   . ASP A 1 161 ? 92.17749  -13.03668 15.00500 1.000 52.21330  ? 162 ASP A CA   1 
ATOM   2496 C C    . ASP A 1 161 ? 91.83754  -14.39797 15.62879 1.000 46.88063  ? 162 ASP A C    1 
ATOM   2497 O O    . ASP A 1 161 ? 92.68175  -15.29896 15.71632 1.000 48.69007  ? 162 ASP A O    1 
ATOM   2498 C CB   . ASP A 1 161 ? 91.95932  -13.14736 13.42592 1.000 55.64962  ? 162 ASP A CB   1 
ATOM   2499 C CG   . ASP A 1 161 ? 91.91978  -11.77369 12.65538 1.000 58.10360  ? 162 ASP A CG   1 
ATOM   2500 O OD1  . ASP A 1 161 ? 92.82362  -10.89727 12.83991 1.000 62.30029  ? 162 ASP A OD1  1 
ATOM   2501 O OD2  . ASP A 1 161 ? 90.99413  -11.63058 11.81191 1.000 57.38736  ? 162 ASP A OD2  1 
ATOM   2502 H H    . ASP A 1 161 ? 94.14008  -13.21177 15.06080 1.000 49.56833  ? 162 ASP A H    1 
ATOM   2503 H HA   . ASP A 1 161 ? 91.57900  -12.36100 15.36022 1.000 62.72722  ? 162 ASP A HA   1 
ATOM   2504 H HB2  . ASP A 1 161 ? 92.68707  -13.66817 13.05171 1.000 66.85081  ? 162 ASP A HB2  1 
ATOM   2505 H HB3  . ASP A 1 161 ? 91.11387  -13.59443 13.26390 1.000 66.85081  ? 162 ASP A HB3  1 
ATOM   2506 N N    . ARG A 1 162 ? 90.57643  -14.56929 16.00836 1.000 45.61984  ? 163 ARG A N    1 
ATOM   2507 C CA   . ARG A 1 162 ? 90.05190  -15.84000 16.48719 1.000 47.87598  ? 163 ARG A CA   1 
ATOM   2508 C C    . ARG A 1 162 ? 88.80953  -16.23615 15.69363 1.000 52.48572  ? 163 ARG A C    1 
ATOM   2509 O O    . ARG A 1 162 ? 87.84181  -15.46934 15.58405 1.000 52.75557  ? 163 ARG A O    1 
ATOM   2510 C CB   . ARG A 1 162 ? 89.67277  -15.78012 18.00723 1.000 49.66302  ? 163 ARG A CB   1 
ATOM   2511 C CG   . ARG A 1 162 ? 89.02963  -17.08238 18.57800 1.000 50.22477  ? 163 ARG A CG   1 
ATOM   2512 C CD   . ARG A 1 162 ? 88.54472  -16.96370 20.04803 1.000 49.13374  ? 163 ARG A CD   1 
ATOM   2513 N NE   . ARG A 1 162 ? 88.03154  -18.20200 20.62637 1.000 48.99418  ? 163 ARG A NE   1 
ATOM   2514 C CZ   . ARG A 1 162 ? 86.78473  -18.63842 20.48582 1.000 52.78268  ? 163 ARG A CZ   1 
ATOM   2515 N NH1  . ARG A 1 162 ? 85.91947  -18.02490 19.71208 1.000 47.71644  ? 163 ARG A NH1  1 
ATOM   2516 N NH2  . ARG A 1 162 ? 86.40461  -19.73893 21.11989 1.000 51.71685  ? 163 ARG A NH2  1 
ATOM   2517 H H    . ARG A 1 162 ? 89.98711  -13.94306 15.99674 1.000 54.81508  ? 163 ARG A H    1 
ATOM   2518 H HA   . ARG A 1 162 ? 90.73915  -16.51087 16.35112 1.000 57.52245  ? 163 ARG A HA   1 
ATOM   2519 H HB2  . ARG A 1 162 ? 90.47873  -15.60571 18.51803 1.000 59.66689  ? 163 ARG A HB2  1 
ATOM   2520 H HB3  . ARG A 1 162 ? 89.03568  -15.06021 18.13662 1.000 59.66689  ? 163 ARG A HB3  1 
ATOM   2521 H HG2  . ARG A 1 162 ? 88.26079  -17.31350 18.03362 1.000 60.34099  ? 163 ARG A HG2  1 
ATOM   2522 H HG3  . ARG A 1 162 ? 89.68713  -17.79468 18.54297 1.000 60.34099  ? 163 ARG A HG3  1 
ATOM   2523 H HD2  . ARG A 1 162 ? 89.29064  -16.67392 20.59623 1.000 59.03176  ? 163 ARG A HD2  1 
ATOM   2524 H HD3  . ARG A 1 162 ? 87.83112  -16.30773 20.08522 1.000 59.03176  ? 163 ARG A HD3  1 
ATOM   2525 H HE   . ARG A 1 162 ? 88.57383  -18.68210 21.09007 1.000 58.86428  ? 163 ARG A HE   1 
ATOM   2526 H HH11 . ARG A 1 162 ? 86.15415  -17.31996 19.27896 1.000 57.33100  ? 163 ARG A HH11 1 
ATOM   2527 H HH12 . ARG A 1 162 ? 85.11802  -18.32797 19.63837 1.000 57.33100  ? 163 ARG A HH12 1 
ATOM   2528 H HH21 . ARG A 1 162 ? 86.96341  -20.16361 21.61688 1.000 62.13149  ? 163 ARG A HH21 1 
ATOM   2529 H HH22 . ARG A 1 162 ? 85.59924  -20.02813 21.03422 1.000 62.13149  ? 163 ARG A HH22 1 
ATOM   2530 N N    . PHE A 1 163 ? 88.78909  -17.46108 15.20331 1.000 49.76519  ? 164 PHE A N    1 
ATOM   2531 C CA   . PHE A 1 163 ? 87.62693  -17.94672 14.46534 1.000 52.55169  ? 164 PHE A CA   1 
ATOM   2532 C C    . PHE A 1 163 ? 87.05179  -19.19326 15.12505 1.000 51.40218  ? 164 PHE A C    1 
ATOM   2533 O O    . PHE A 1 163 ? 87.78924  -20.13380 15.45581 1.000 49.11494  ? 164 PHE A O    1 
ATOM   2534 C CB   . PHE A 1 163 ? 88.00366  -18.26700 13.01621 1.000 51.41524  ? 164 PHE A CB   1 
ATOM   2535 C CG   . PHE A 1 163 ? 88.22622  -17.04721 12.13216 1.000 51.82490  ? 164 PHE A CG   1 
ATOM   2536 C CD1  . PHE A 1 163 ? 89.49382  -16.48071 11.99559 1.000 48.30301  ? 164 PHE A CD1  1 
ATOM   2537 C CD2  . PHE A 1 163 ? 87.16256  -16.53049 11.36302 1.000 53.19081  ? 164 PHE A CD2  1 
ATOM   2538 C CE1  . PHE A 1 163 ? 89.69097  -15.37912 11.13289 1.000 53.33996  ? 164 PHE A CE1  1 
ATOM   2539 C CE2  . PHE A 1 163 ? 87.35586  -15.45241 10.50073 1.000 50.03026  ? 164 PHE A CE2  1 
ATOM   2540 C CZ   . PHE A 1 163 ? 88.61275  -14.86392 10.41084 1.000 55.07052  ? 164 PHE A CZ   1 
ATOM   2541 H H    . PHE A 1 163 ? 89.42970  -18.02943 15.28202 1.000 59.78950  ? 164 PHE A H    1 
ATOM   2542 H HA   . PHE A 1 163 ? 86.94202  -17.26004 14.48174 1.000 63.13329  ? 164 PHE A HA   1 
ATOM   2543 H HB2  . PHE A 1 163 ? 88.82662  -18.78045 13.01797 1.000 61.76956  ? 164 PHE A HB2  1 
ATOM   2544 H HB3  . PHE A 1 163 ? 87.28818  -18.78836 12.61976 1.000 61.76956  ? 164 PHE A HB3  1 
ATOM   2545 H HD1  . PHE A 1 163 ? 90.21128  -16.82920 12.47383 1.000 58.03488  ? 164 PHE A HD1  1 
ATOM   2546 H HD2  . PHE A 1 163 ? 86.31875  -16.91530 11.43236 1.000 63.90024  ? 164 PHE A HD2  1 
ATOM   2547 H HE1  . PHE A 1 163 ? 90.53528  -14.99891 11.04643 1.000 64.07922  ? 164 PHE A HE1  1 
ATOM   2548 H HE2  . PHE A 1 163 ? 86.64956  -15.12909 9.98934  1.000 60.10758  ? 164 PHE A HE2  1 
ATOM   2549 H HZ   . PHE A 1 163 ? 88.73608  -14.12098 9.86520  1.000 66.15589  ? 164 PHE A HZ   1 
ATOM   2550 N N    . ALA A 1 164 ? 85.73999  -19.20994 15.28357 1.000 51.15871  ? 165 ALA A N    1 
ATOM   2551 C CA   . ALA A 1 164 ? 84.99958  -20.42352 15.58615 1.000 53.81831  ? 165 ALA A CA   1 
ATOM   2552 C C    . ALA A 1 164 ? 84.29652  -20.93843 14.33665 1.000 57.12939  ? 165 ALA A C    1 
ATOM   2553 O O    . ALA A 1 164 ? 83.68694  -20.16362 13.59890 1.000 56.48167  ? 165 ALA A O    1 
ATOM   2554 C CB   . ALA A 1 164 ? 83.95138  -20.16482 16.66609 1.000 56.78889  ? 165 ALA A CB   1 
ATOM   2555 H H    . ALA A 1 164 ? 85.24166  -18.51200 15.21916 1.000 61.46172  ? 165 ALA A H    1 
ATOM   2556 H HA   . ALA A 1 164 ? 85.62039  -21.09958 15.89987 1.000 64.65324  ? 165 ALA A HA   1 
ATOM   2557 H HB1  . ALA A 1 164 ? 83.49433  -20.99618 16.86818 1.000 68.21794  ? 165 ALA A HB1  1 
ATOM   2558 H HB2  . ALA A 1 164 ? 84.39357  -19.82868 17.46131 1.000 68.21794  ? 165 ALA A HB2  1 
ATOM   2559 H HB3  . ALA A 1 164 ? 83.31592  -19.50909 16.33879 1.000 68.21794  ? 165 ALA A HB3  1 
ATOM   2560 N N    . LEU A 1 165 ? 84.38899  -22.24865 14.10120 1.000 63.81345  ? 166 LEU A N    1 
ATOM   2561 C CA   . LEU A 1 165 ? 83.78111  -22.89076 12.94094 1.000 61.43693  ? 166 LEU A CA   1 
ATOM   2562 C C    . LEU A 1 165 ? 82.56714  -23.74311 13.31395 1.000 61.78107  ? 166 LEU A C    1 
ATOM   2563 O O    . LEU A 1 165 ? 82.31249  -24.06689 14.47980 1.000 69.30218  ? 166 LEU A O    1 
ATOM   2564 C CB   . LEU A 1 165 ? 84.80514  -23.76154 12.19574 1.000 60.42697  ? 166 LEU A CB   1 
ATOM   2565 C CG   . LEU A 1 165 ? 85.95007  -23.01795 11.49077 1.000 56.80364  ? 166 LEU A CG   1 
ATOM   2566 C CD1  . LEU A 1 165 ? 86.92380  -22.45894 12.53073 1.000 52.64866  ? 166 LEU A CD1  1 
ATOM   2567 C CD2  . LEU A 1 165 ? 86.68535  -23.87598 10.49987 1.000 59.52143  ? 166 LEU A CD2  1 
ATOM   2568 H H    . LEU A 1 165 ? 84.80946  -22.79680 14.61338 1.000 76.64741  ? 166 LEU A H    1 
ATOM   2569 H HA   . LEU A 1 165 ? 83.46446  -22.18938 12.35044 1.000 73.79558  ? 166 LEU A HA   1 
ATOM   2570 H HB2  . LEU A 1 165 ? 85.20978  -24.36587 12.83758 1.000 72.58363  ? 166 LEU A HB2  1 
ATOM   2571 H HB3  . LEU A 1 165 ? 84.33221  -24.26722 11.51638 1.000 72.58363  ? 166 LEU A HB3  1 
ATOM   2572 H HG   . LEU A 1 165 ? 85.55912  -22.28948 10.98344 1.000 68.23563  ? 166 LEU A HG   1 
ATOM   2573 H HD11 . LEU A 1 165 ? 87.78038  -22.29589 12.10579 1.000 63.24966  ? 166 LEU A HD11 1 
ATOM   2574 H HD12 . LEU A 1 165 ? 86.56653  -21.62919 12.88398 1.000 63.24966  ? 166 LEU A HD12 1 
ATOM   2575 H HD13 . LEU A 1 165 ? 87.02728  -23.10567 13.24622 1.000 63.24966  ? 166 LEU A HD13 1 
ATOM   2576 H HD21 . LEU A 1 165 ? 87.40978  -23.36050 10.11208 1.000 71.49699  ? 166 LEU A HD21 1 
ATOM   2577 H HD22 . LEU A 1 165 ? 87.04096  -24.65350 10.95803 1.000 71.49699  ? 166 LEU A HD22 1 
ATOM   2578 H HD23 . LEU A 1 165 ? 86.06882  -24.15483 9.80487  1.000 71.49699  ? 166 LEU A HD23 1 
ATOM   2579 N N    . ARG A 1 166 ? 81.80528  -24.09281 12.28697 1.000 66.60641  ? 167 ARG A N    1 
ATOM   2580 C CA   . ARG A 1 166 ? 80.62461  -24.93400 12.44379 1.000 67.61059  ? 167 ARG A CA   1 
ATOM   2581 C C    . ARG A 1 166 ? 80.44712  -25.72547 11.15576 1.000 72.62713  ? 167 ARG A C    1 
ATOM   2582 O O    . ARG A 1 166 ? 80.08087  -25.16276 10.11181 1.000 68.74314  ? 167 ARG A O    1 
ATOM   2583 C CB   . ARG A 1 166 ? 79.38113  -24.11322 12.75683 1.000 62.43957  ? 167 ARG A CB   1 
ATOM   2584 C CG   . ARG A 1 166 ? 78.13886  -24.95753 12.65939 1.000 63.50227  ? 167 ARG A CG   1 
ATOM   2585 C CD   . ARG A 1 166 ? 77.03866  -24.38810 13.51373 1.000 67.25243  ? 167 ARG A CD   1 
ATOM   2586 N NE   . ARG A 1 166 ? 76.27567  -23.35422 12.82913 1.000 79.98013  ? 167 ARG A NE   1 
ATOM   2587 C CZ   . ARG A 1 166 ? 76.32671  -22.06090 13.11894 1.000 78.15363  ? 167 ARG A CZ   1 
ATOM   2588 N NH1  . ARG A 1 166 ? 77.10447  -21.59681 14.08362 1.000 82.03197  ? 167 ARG A NH1  1 
ATOM   2589 N NH2  . ARG A 1 166 ? 75.57361  -21.21028 12.42574 1.000 84.51779  ? 167 ARG A NH2  1 
ATOM   2590 H H    . ARG A 1 166 ? 81.95214  -23.85243 11.47441 1.000 79.99895  ? 167 ARG A H    1 
ATOM   2591 H HA   . ARG A 1 166 ? 80.76862  -25.55122 13.17809 1.000 81.20397  ? 167 ARG A HA   1 
ATOM   2592 H HB2  . ARG A 1 166 ? 79.44497  -23.76256 13.65898 1.000 74.99875  ? 167 ARG A HB2  1 
ATOM   2593 H HB3  . ARG A 1 166 ? 79.30805  -23.38369 12.12174 1.000 74.99875  ? 167 ARG A HB3  1 
ATOM   2594 H HG2  . ARG A 1 166 ? 77.83366  -24.98011 11.73893 1.000 76.27399  ? 167 ARG A HG2  1 
ATOM   2595 H HG3  . ARG A 1 166 ? 78.33323  -25.85683 12.96662 1.000 76.27399  ? 167 ARG A HG3  1 
ATOM   2596 H HD2  . ARG A 1 166 ? 76.42710  -25.10008 13.75865 1.000 80.77419  ? 167 ARG A HD2  1 
ATOM   2597 H HD3  . ARG A 1 166 ? 77.42760  -23.99590 14.31111 1.000 80.77419  ? 167 ARG A HD3  1 
ATOM   2598 H HE   . ARG A 1 166 ? 75.75428  -23.59979 12.19081 1.000 96.04742  ? 167 ARG A HE   1 
ATOM   2599 H HH11 . ARG A 1 166 ? 77.59282  -22.13792 14.54003 1.000 98.50963  ? 167 ARG A HH11 1 
ATOM   2600 H HH12 . ARG A 1 166 ? 77.12161  -20.75407 14.25419 1.000 98.50963  ? 167 ARG A HH12 1 
ATOM   2601 H HH21 . ARG A 1 166 ? 75.06207  -21.50140 11.79870 1.000 101.49261 ? 167 ARG A HH21 1 
ATOM   2602 H HH22 . ARG A 1 166 ? 75.59852  -20.36950 12.60483 1.000 101.49261 ? 167 ARG A HH22 1 
ATOM   2603 N N    . ASP A 1 167 ? 80.71159  -27.02783 11.23230 1.000 81.03264  ? 168 ASP A N    1 
ATOM   2604 C CA   . ASP A 1 167 ? 80.62755  -27.92458 10.07742 1.000 79.53271  ? 168 ASP A CA   1 
ATOM   2605 C C    . ASP A 1 167 ? 81.49184  -27.41056 8.93359  1.000 72.76955  ? 168 ASP A C    1 
ATOM   2606 O O    . ASP A 1 167 ? 81.06403  -27.36067 7.78378  1.000 79.20775  ? 168 ASP A O    1 
ATOM   2607 C CB   . ASP A 1 167 ? 79.17808  -28.10155 9.62433  1.000 76.86200  ? 168 ASP A CB   1 
ATOM   2608 C CG   . ASP A 1 167 ? 78.27728  -28.63405 10.74329 1.000 88.80746  ? 168 ASP A CG   1 
ATOM   2609 O OD1  . ASP A 1 167 ? 78.73025  -29.45768 11.58378 1.000 126.40388 ? 168 ASP A OD1  1 
ATOM   2610 O OD2  . ASP A 1 167 ? 77.10245  -28.19615 10.78508 1.000 90.31065  ? 168 ASP A OD2  1 
ATOM   2611 H H    . ASP A 1 167 ? 80.94708  -27.42618 11.95719 1.000 97.31044  ? 168 ASP A H    1 
ATOM   2612 H HA   . ASP A 1 167 ? 80.96653  -28.79498 10.33896 1.000 95.51052  ? 168 ASP A HA   1 
ATOM   2613 H HB2  . ASP A 1 167 ? 78.82794  -27.24341 9.33815  1.000 92.30567  ? 168 ASP A HB2  1 
ATOM   2614 H HB3  . ASP A 1 167 ? 79.15032  -28.73321 8.88871  1.000 92.30567  ? 168 ASP A HB3  1 
ATOM   2615 N N    . GLY A 1 168 ? 82.70851  -26.97700 9.26452  1.000 72.13738  ? 169 GLY A N    1 
ATOM   2616 C CA   . GLY A 1 168 ? 83.64930  -26.51984 8.26243  1.000 76.28297  ? 169 GLY A CA   1 
ATOM   2617 C C    . GLY A 1 168 ? 83.52000  -25.07291 7.81665  1.000 63.10608  ? 169 GLY A C    1 
ATOM   2618 O O    . GLY A 1 168 ? 84.44096  -24.57802 7.15550  1.000 53.62929  ? 169 GLY A O    1 
ATOM   2619 H H    . GLY A 1 168 ? 83.00768  -26.94056 10.06998 1.000 86.63612  ? 169 GLY A H    1 
ATOM   2620 H HA2  . GLY A 1 168 ? 84.54622  -26.63413 8.61367  1.000 91.61083  ? 169 GLY A HA2  1 
ATOM   2621 H HA3  . GLY A 1 168 ? 83.54597  -27.07477 7.47358  1.000 91.61083  ? 169 GLY A HA3  1 
ATOM   2622 N N    . LYS A 1 169 ? 82.42730  -24.38686 8.15234  1.000 59.35668  ? 170 LYS A N    1 
ATOM   2623 C CA   . LYS A 1 169 ? 82.19561  -23.00006 7.77705  1.000 63.05044  ? 170 LYS A CA   1 
ATOM   2624 C C    . LYS A 1 169 ? 82.46422  -22.05651 8.94774  1.000 63.79003  ? 170 LYS A C    1 
ATOM   2625 O O    . LYS A 1 169 ? 82.27649  -22.42150 10.10709 1.000 62.57829  ? 170 LYS A O    1 
ATOM   2626 C CB   . LYS A 1 169 ? 80.75670  -22.82718 7.27906  1.000 64.22259  ? 170 LYS A CB   1 
ATOM   2627 C CG   . LYS A 1 169 ? 80.50620  -23.50710 5.92250  1.000 71.05195  ? 170 LYS A CG   1 
ATOM   2628 C CD   . LYS A 1 169 ? 79.66468  -22.63555 4.98419  1.000 79.42046  ? 170 LYS A CD   1 
ATOM   2629 C CE   . LYS A 1 169 ? 79.58299  -23.21055 3.55720  1.000 84.93800  ? 170 LYS A CE   1 
ATOM   2630 N NZ   . LYS A 1 169 ? 80.90505  -23.65999 3.00551  1.000 80.85470  ? 170 LYS A NZ   1 
ATOM   2631 H H    . LYS A 1 169 ? 81.78332  -24.71947 8.61523  1.000 71.29928  ? 170 LYS A H    1 
ATOM   2632 H HA   . LYS A 1 169 ? 82.80684  -22.75155 7.06604  1.000 75.73179  ? 170 LYS A HA   1 
ATOM   2633 H HB2  . LYS A 1 169 ? 80.15003  -23.21851 7.92691  1.000 77.13837  ? 170 LYS A HB2  1 
ATOM   2634 H HB3  . LYS A 1 169 ? 80.56965  -21.88067 7.17890  1.000 77.13837  ? 170 LYS A HB3  1 
ATOM   2635 H HG2  . LYS A 1 169 ? 81.35748  -23.68038 5.49099  1.000 85.33361  ? 170 LYS A HG2  1 
ATOM   2636 H HG3  . LYS A 1 169 ? 80.03162  -24.34068 6.06676  1.000 85.33361  ? 170 LYS A HG3  1 
ATOM   2637 H HD2  . LYS A 1 169 ? 78.76236  -22.57205 5.33444  1.000 95.37582  ? 170 LYS A HD2  1 
ATOM   2638 H HD3  . LYS A 1 169 ? 80.06236  -21.75249 4.92978  1.000 95.37582  ? 170 LYS A HD3  1 
ATOM   2639 H HE2  . LYS A 1 169 ? 78.99001  -23.97816 3.56375  1.000 101.99687 ? 170 LYS A HE2  1 
ATOM   2640 H HE3  . LYS A 1 169 ? 79.23360  -22.52648 2.96486  1.000 101.99687 ? 170 LYS A HE3  1 
ATOM   2641 H HZ1  . LYS A 1 169 ? 80.81098  -23.91231 2.15723  1.000 97.09690  ? 170 LYS A HZ1  1 
ATOM   2642 H HZ2  . LYS A 1 169 ? 81.49376  -22.99369 3.04507  1.000 97.09690  ? 170 LYS A HZ2  1 
ATOM   2643 H HZ3  . LYS A 1 169 ? 81.21453  -24.34733 3.47868  1.000 97.09690  ? 170 LYS A HZ3  1 
ATOM   2644 N N    . LEU A 1 170 ? 82.90714  -20.83363 8.63009  1.000 58.39587  ? 171 LEU A N    1 
ATOM   2645 C CA   . LEU A 1 170 ? 83.24632  -19.85719 9.65514  1.000 53.50118  ? 171 LEU A CA   1 
ATOM   2646 C C    . LEU A 1 170 ? 81.98177  -19.27063 10.26576 1.000 56.55338  ? 171 LEU A C    1 
ATOM   2647 O O    . LEU A 1 170 ? 81.09284  -18.80503 9.55031  1.000 57.16537  ? 171 LEU A O    1 
ATOM   2648 C CB   . LEU A 1 170 ? 84.09320  -18.73400 9.09363  1.000 51.92449  ? 171 LEU A CB   1 
ATOM   2649 C CG   . LEU A 1 170 ? 85.26681  -19.24179 8.28261  1.000 55.22087  ? 171 LEU A CG   1 
ATOM   2650 C CD1  . LEU A 1 170 ? 86.11912  -18.08898 7.79539  1.000 55.90397  ? 171 LEU A CD1  1 
ATOM   2651 C CD2  . LEU A 1 170 ? 86.11726  -20.18212 9.09190  1.000 53.71112  ? 171 LEU A CD2  1 
ATOM   2652 H H    . LEU A 1 170 ? 83.01785  -20.55084 7.82550  1.000 70.14632  ? 171 LEU A H    1 
ATOM   2653 H HA   . LEU A 1 170 ? 83.75696  -20.30986 10.34451 1.000 64.27268  ? 171 LEU A HA   1 
ATOM   2654 H HB2  . LEU A 1 170 ? 83.54317  -18.18209 8.51591  1.000 62.38066  ? 171 LEU A HB2  1 
ATOM   2655 H HB3  . LEU A 1 170 ? 84.44041  -18.20299 9.82737  1.000 62.38066  ? 171 LEU A HB3  1 
ATOM   2656 H HG   . LEU A 1 170 ? 84.91725  -19.72251 7.51605  1.000 66.33631  ? 171 LEU A HG   1 
ATOM   2657 H HD11 . LEU A 1 170 ? 86.84853  -18.43949 7.26059  1.000 67.15603  ? 171 LEU A HD11 1 
ATOM   2658 H HD12 . LEU A 1 170 ? 85.57077  -17.49565 7.25858  1.000 67.15603  ? 171 LEU A HD12 1 
ATOM   2659 H HD13 . LEU A 1 170 ? 86.47134  -17.61052 8.56214  1.000 67.15603  ? 171 LEU A HD13 1 
ATOM   2660 H HD21 . LEU A 1 170 ? 86.95917  -20.32247 8.63105  1.000 64.52461  ? 171 LEU A HD21 1 
ATOM   2661 H HD22 . LEU A 1 170 ? 86.27904  -19.79014 9.96430  1.000 64.52461  ? 171 LEU A HD22 1 
ATOM   2662 H HD23 . LEU A 1 170 ? 85.64923  -21.02605 9.19010  1.000 64.52461  ? 171 LEU A HD23 1 
ATOM   2663 N N    . ALA A 1 171 ? 81.89764  -19.29057 11.59332 1.000 54.04457  ? 172 ALA A N    1 
ATOM   2664 C CA   . ALA A 1 171 ? 80.68339  -18.88309 12.28380 1.000 54.42065  ? 172 ALA A CA   1 
ATOM   2665 C C    . ALA A 1 171 ? 80.86292  -17.66583 13.16922 1.000 57.23264  ? 172 ALA A C    1 
ATOM   2666 O O    . ALA A 1 171 ? 79.91721  -16.88727 13.31045 1.000 55.05825  ? 172 ALA A O    1 
ATOM   2667 C CB   . ALA A 1 171 ? 80.14076  -20.03761 13.14242 1.000 54.08680  ? 172 ALA A CB   1 
ATOM   2668 H H    . ALA A 1 171 ? 82.53450  -19.53760 12.11581 1.000 64.92475  ? 172 ALA A H    1 
ATOM   2669 H HA   . ALA A 1 171 ? 80.01178  -18.66674 11.61820 1.000 65.37605  ? 172 ALA A HA   1 
ATOM   2670 H HB1  . ALA A 1 171 ? 79.33013  -19.74579 13.58808 1.000 64.97543  ? 172 ALA A HB1  1 
ATOM   2671 H HB2  . ALA A 1 171 ? 79.94803  -20.79497 12.56782 1.000 64.97543  ? 172 ALA A HB2  1 
ATOM   2672 H HB3  . ALA A 1 171 ? 80.80981  -20.28339 13.80034 1.000 64.97543  ? 172 ALA A HB3  1 
ATOM   2673 N N    . VAL A 1 172 ? 82.04436  -17.47833 13.75666 1.000 55.83015  ? 173 VAL A N    1 
ATOM   2674 C CA   . VAL A 1 172 ? 82.32254  -16.34826 14.63397 1.000 53.96113  ? 173 VAL A CA   1 
ATOM   2675 C C    . VAL A 1 172 ? 83.75032  -15.88474 14.36777 1.000 54.84188  ? 173 VAL A C    1 
ATOM   2676 O O    . VAL A 1 172 ? 84.68598  -16.70058 14.38371 1.000 54.10431  ? 173 VAL A O    1 
ATOM   2677 C CB   . VAL A 1 172 ? 82.17074  -16.68016 16.13556 1.000 52.86671  ? 173 VAL A CB   1 
ATOM   2678 C CG1  . VAL A 1 172 ? 82.51343  -15.44508 16.96696 1.000 55.25238  ? 173 VAL A CG1  1 
ATOM   2679 C CG2  . VAL A 1 172 ? 80.76683  -17.16857 16.46499 1.000 53.02543  ? 173 VAL A CG2  1 
ATOM   2680 H H    . VAL A 1 172 ? 82.71553  -18.00695 13.65816 1.000 67.06745  ? 173 VAL A H    1 
ATOM   2681 H HA   . VAL A 1 172 ? 81.69451  -15.64125 14.41808 1.000 64.82462  ? 173 VAL A HA   1 
ATOM   2682 H HB   . VAL A 1 172 ? 82.78257  -17.39924 16.35805 1.000 63.51132  ? 173 VAL A HB   1 
ATOM   2683 H HG11 . VAL A 1 172 ? 82.23599  -15.59495 17.88427 1.000 66.37412  ? 173 VAL A HG11 1 
ATOM   2684 H HG12 . VAL A 1 172 ? 83.47126  -15.29614 16.93121 1.000 66.37412  ? 173 VAL A HG12 1 
ATOM   2685 H HG13 . VAL A 1 172 ? 82.04555  -14.67825 16.60096 1.000 66.37412  ? 173 VAL A HG13 1 
ATOM   2686 H HG21 . VAL A 1 172 ? 80.71072  -17.35016 17.41619 1.000 63.70179  ? 173 VAL A HG21 1 
ATOM   2687 H HG22 . VAL A 1 172 ? 80.12785  -16.48066 16.22131 1.000 63.70179  ? 173 VAL A HG22 1 
ATOM   2688 H HG23 . VAL A 1 172 ? 80.58831  -17.97882 15.96247 1.000 63.70179  ? 173 VAL A HG23 1 
ATOM   2689 N N    . GLN A 1 173 ? 83.92601  -14.57181 14.17517 1.000 55.06724  ? 174 GLN A N    1 
ATOM   2690 C CA   . GLN A 1 173 ? 85.24740  -13.94532 14.11896 1.000 55.44171  ? 174 GLN A CA   1 
ATOM   2691 C C    . GLN A 1 173 ? 85.38243  -12.89025 15.22119 1.000 57.08079  ? 174 GLN A C    1 
ATOM   2692 O O    . GLN A 1 173 ? 84.47977  -12.07241 15.42160 1.000 55.87259  ? 174 GLN A O    1 
ATOM   2693 C CB   . GLN A 1 173 ? 85.46420  -13.32472 12.74303 1.000 53.88175  ? 174 GLN A CB   1 
ATOM   2694 C CG   . GLN A 1 173 ? 86.77654  -12.58900 12.59581 1.000 50.88307  ? 174 GLN A CG   1 
ATOM   2695 C CD   . GLN A 1 173 ? 86.95033  -11.95103 11.19728 1.000 54.97336  ? 174 GLN A CD   1 
ATOM   2696 O OE1  . GLN A 1 173 ? 85.97847  -11.73190 10.45628 1.000 52.68342  ? 174 GLN A OE1  1 
ATOM   2697 N NE2  . GLN A 1 173 ? 88.18792  -11.62985 10.87720 1.000 47.85162  ? 174 GLN A NE2  1 
ATOM   2698 H H    . GLN A 1 173 ? 83.27935  -14.01423 14.07257 1.000 66.15196  ? 174 GLN A H    1 
ATOM   2699 H HA   . GLN A 1 173 ? 85.93607  -14.60873 14.28184 1.000 66.60132  ? 174 GLN A HA   1 
ATOM   2700 H HB2  . GLN A 1 173 ? 85.44623  -14.03063 12.07800 1.000 64.72937  ? 174 GLN A HB2  1 
ATOM   2701 H HB3  . GLN A 1 173 ? 84.75037  -12.69037 12.57287 1.000 64.72937  ? 174 GLN A HB3  1 
ATOM   2702 H HG2  . GLN A 1 173 ? 86.81731  -11.87980 13.25632 1.000 61.13095  ? 174 GLN A HG2  1 
ATOM   2703 H HG3  . GLN A 1 173 ? 87.50617  -13.21313 12.73370 1.000 61.13095  ? 174 GLN A HG3  1 
ATOM   2704 H HE21 . GLN A 1 173 ? 88.82804  -11.77914 11.43178 1.000 57.49321  ? 174 GLN A HE21 1 
ATOM   2705 H HE22 . GLN A 1 173 ? 88.35530  -11.27100 10.11379 1.000 57.49321  ? 174 GLN A HE22 1 
ATOM   2706 N N    . ASP A 1 174 ? 86.50409  -12.90950 15.93370 1.000 46.64716  ? 175 ASP A N    1 
ATOM   2707 C CA   . ASP A 1 174 ? 86.86710  -11.87939 16.90124 1.000 52.06986  ? 175 ASP A CA   1 
ATOM   2708 C C    . ASP A 1 174 ? 88.25129  -11.33838 16.54572 1.000 46.97532  ? 175 ASP A C    1 
ATOM   2709 O O    . ASP A 1 174 ? 89.16402  -12.08608 16.11255 1.000 42.31150  ? 175 ASP A O    1 
ATOM   2710 C CB   . ASP A 1 174 ? 86.81488  -12.42735 18.33719 1.000 53.73260  ? 175 ASP A CB   1 
ATOM   2711 C CG   . ASP A 1 174 ? 85.37490  -12.50779 18.85485 1.000 57.71356  ? 175 ASP A CG   1 
ATOM   2712 O OD1  . ASP A 1 174 ? 84.85758  -11.45629 19.30099 1.000 64.87035  ? 175 ASP A OD1  1 
ATOM   2713 O OD2  . ASP A 1 174 ? 84.75885  -13.60060 18.75392 1.000 53.42318  ? 175 ASP A OD2  1 
ATOM   2714 H H    . ASP A 1 174 ? 87.09321  -13.53296 15.87177 1.000 56.04786  ? 175 ASP A H    1 
ATOM   2715 H HA   . ASP A 1 174 ? 86.24569  -11.13540 16.86612 1.000 62.55509  ? 175 ASP A HA   1 
ATOM   2716 H HB2  . ASP A 1 174 ? 87.19588  -13.31922 18.35450 1.000 64.55039  ? 175 ASP A HB2  1 
ATOM   2717 H HB3  . ASP A 1 174 ? 87.31772  -11.84035 18.92327 1.000 64.55039  ? 175 ASP A HB3  1 
ATOM   2718 N N    . VAL A 1 175 ? 88.42337  -10.02491 16.69608 1.000 46.39907  ? 176 VAL A N    1 
ATOM   2719 C CA   . VAL A 1 175 ? 89.66245  -9.37984  16.25192 1.000 49.82427  ? 176 VAL A CA   1 
ATOM   2720 C C    . VAL A 1 175 ? 90.14753  -8.42472  17.32769 1.000 50.02961  ? 176 VAL A C    1 
ATOM   2721 O O    . VAL A 1 175 ? 89.34458  -7.66673  17.88817 1.000 48.24151  ? 176 VAL A O    1 
ATOM   2722 C CB   . VAL A 1 175 ? 89.47296  -8.61595  14.91125 1.000 50.99620  ? 176 VAL A CB   1 
ATOM   2723 C CG1  . VAL A 1 175 ? 90.78081  -7.92535  14.52994 1.000 49.49153  ? 176 VAL A CG1  1 
ATOM   2724 C CG2  . VAL A 1 175 ? 89.02941  -9.55938  13.77715 1.000 53.66552  ? 176 VAL A CG2  1 
ATOM   2725 H H    . VAL A 1 175 ? 87.84566  -9.49345  17.04736 1.000 55.75015  ? 176 VAL A H    1 
ATOM   2726 H HA   . VAL A 1 175 ? 90.33486  -10.06778 16.12740 1.000 59.86039  ? 176 VAL A HA   1 
ATOM   2727 H HB   . VAL A 1 175 ? 88.77425  -7.95370  15.03015 1.000 61.26671  ? 176 VAL A HB   1 
ATOM   2728 H HG11 . VAL A 1 175 ? 90.72254  -7.62475  13.60953 1.000 59.46110  ? 176 VAL A HG11 1 
ATOM   2729 H HG12 . VAL A 1 175 ? 90.92016  -7.16633  15.11761 1.000 59.46110  ? 176 VAL A HG12 1 
ATOM   2730 H HG13 . VAL A 1 175 ? 91.51099  -8.55661  14.62614 1.000 59.46110  ? 176 VAL A HG13 1 
ATOM   2731 H HG21 . VAL A 1 175 ? 88.91185  -9.04291  12.96453 1.000 64.46989  ? 176 VAL A HG21 1 
ATOM   2732 H HG22 . VAL A 1 175 ? 89.71208  -10.23541 13.64357 1.000 64.46989  ? 176 VAL A HG22 1 
ATOM   2733 H HG23 . VAL A 1 175 ? 88.19150  -9.98004  14.02584 1.000 64.46989  ? 176 VAL A HG23 1 
ATOM   2734 N N    . TRP A 1 176 ? 91.46298  -8.42081  17.56011 1.000 43.93710  ? 177 TRP A N    1 
ATOM   2735 C CA   . TRP A 1 176 ? 92.10627  -7.52309  18.50223 1.000 50.65455  ? 177 TRP A CA   1 
ATOM   2736 C C    . TRP A 1 176 ? 93.41026  -7.08104  17.84578 1.000 49.30450  ? 177 TRP A C    1 
ATOM   2737 O O    . TRP A 1 176 ? 94.11610  -7.91876  17.23956 1.000 49.90846  ? 177 TRP A O    1 
ATOM   2738 C CB   . TRP A 1 176 ? 92.44278  -8.16501  19.86174 1.000 50.66312  ? 177 TRP A CB   1 
ATOM   2739 C CG   . TRP A 1 176 ? 91.32071  -8.81740  20.64355 1.000 50.08635  ? 177 TRP A CG   1 
ATOM   2740 C CD1  . TRP A 1 176 ? 90.63937  -8.29020  21.67872 1.000 51.19567  ? 177 TRP A CD1  1 
ATOM   2741 C CD2  . TRP A 1 176 ? 90.79910  -10.13514 20.44134 1.000 53.05476  ? 177 TRP A CD2  1 
ATOM   2742 N NE1  . TRP A 1 176 ? 89.70886  -9.18926  22.15456 1.000 47.83306  ? 177 TRP A NE1  1 
ATOM   2743 C CE2  . TRP A 1 176 ? 89.78048  -10.33028 21.40931 1.000 50.20819  ? 177 TRP A CE2  1 
ATOM   2744 C CE3  . TRP A 1 176 ? 91.08091  -11.16846 19.51201 1.000 46.17519  ? 177 TRP A CE3  1 
ATOM   2745 C CZ2  . TRP A 1 176 ? 89.03909  -11.50933 21.50905 1.000 46.37122  ? 177 TRP A CZ2  1 
ATOM   2746 C CZ3  . TRP A 1 176 ? 90.34076  -12.36654 19.62501 1.000 52.80294  ? 177 TRP A CZ3  1 
ATOM   2747 C CH2  . TRP A 1 176 ? 89.32283  -12.50766 20.60977 1.000 52.36836  ? 177 TRP A CH2  1 
ATOM   2748 H H    . TRP A 1 176 ? 92.01646  -8.94925  17.16768 1.000 52.79579  ? 177 TRP A H    1 
ATOM   2749 H HA   . TRP A 1 176 ? 91.51254  -6.77929  18.68973 1.000 60.85673  ? 177 TRP A HA   1 
ATOM   2750 H HB2  . TRP A 1 176 ? 93.10795  -8.85355  19.70569 1.000 60.86701  ? 177 TRP A HB2  1 
ATOM   2751 H HB3  . TRP A 1 176 ? 92.81043  -7.47166  20.43183 1.000 60.86701  ? 177 TRP A HB3  1 
ATOM   2752 H HD1  . TRP A 1 176 ? 90.77742  -7.43800  22.02454 1.000 61.50607  ? 177 TRP A HD1  1 
ATOM   2753 H HE1  . TRP A 1 176 ? 89.17188  -9.05348  22.81245 1.000 57.47094  ? 177 TRP A HE1  1 
ATOM   2754 H HE3  . TRP A 1 176 ? 91.72843  -11.06154 18.85309 1.000 55.48150  ? 177 TRP A HE3  1 
ATOM   2755 H HZ2  . TRP A 1 176 ? 88.38065  -11.61415 22.15741 1.000 55.71673  ? 177 TRP A HZ2  1 
ATOM   2756 H HZ3  . TRP A 1 176 ? 90.52121  -13.07301 19.04776 1.000 63.43480  ? 177 TRP A HZ3  1 
ATOM   2757 H HH2  . TRP A 1 176 ? 88.83566  -13.29906 20.64525 1.000 62.91330  ? 177 TRP A HH2  1 
ATOM   2758 N N    . ASN A 1 177 ? 93.76462  -5.78595  17.98444 1.000 49.05495  ? 178 ASN A N    1 
ATOM   2759 C CA   . ASN A 1 177 ? 95.04008  -5.34265  17.41105 1.000 55.52137  ? 178 ASN A CA   1 
ATOM   2760 C C    . ASN A 1 177 ? 95.49173  -4.02596  18.03415 1.000 53.83128  ? 178 ASN A C    1 
ATOM   2761 O O    . ASN A 1 177 ? 94.76791  -3.37858  18.80937 1.000 48.61230  ? 178 ASN A O    1 
ATOM   2762 C CB   . ASN A 1 177 ? 94.95002  -5.18994  15.86623 1.000 51.20410  ? 178 ASN A CB   1 
ATOM   2763 C CG   . ASN A 1 177 ? 93.89725  -4.14644  15.45692 1.000 53.90635  ? 178 ASN A CG   1 
ATOM   2764 O OD1  . ASN A 1 177 ? 93.96926  -2.95972  15.83744 1.000 55.86500  ? 178 ASN A OD1  1 
ATOM   2765 N ND2  . ASN A 1 177 ? 92.88447  -4.59807  14.73774 1.000 57.60373  ? 178 ASN A ND2  1 
ATOM   2766 H H    . ASN A 1 177 ? 93.30321  -5.18162  18.38629 1.000 58.93721  ? 178 ASN A H    1 
ATOM   2767 H HA   . ASN A 1 177 ? 95.70081  -6.01531  17.63878 1.000 66.69691  ? 178 ASN A HA   1 
ATOM   2768 H HB2  . ASN A 1 177 ? 95.81090  -4.90456  15.52223 1.000 61.51619  ? 178 ASN A HB2  1 
ATOM   2769 H HB3  . ASN A 1 177 ? 94.70210  -6.04196  15.47444 1.000 61.51619  ? 178 ASN A HB3  1 
ATOM   2770 H HD21 . ASN A 1 177 ? 92.84432  -5.43090  14.52703 1.000 69.19575  ? 178 ASN A HD21 1 
ATOM   2771 H HD22 . ASN A 1 177 ? 92.26564  -4.05912  14.48049 1.000 69.19575  ? 178 ASN A HD22 1 
ATOM   2772 N N    . ASP A 1 178 ? 96.71800  -3.64566  17.65369 1.000 51.35302  ? 179 ASP A N    1 
ATOM   2773 C CA   . ASP A 1 178 ? 97.44161  -2.50605  18.18696 1.000 53.82437  ? 179 ASP A CA   1 
ATOM   2774 C C    . ASP A 1 178 ? 97.24205  -1.22937  17.34022 1.000 56.06978  ? 179 ASP A C    1 
ATOM   2775 O O    . ASP A 1 178 ? 98.03304  -0.29617  17.46974 1.000 55.34649  ? 179 ASP A O    1 
ATOM   2776 C CB   . ASP A 1 178 ? 98.95178  -2.82828  18.25844 1.000 47.96146  ? 179 ASP A CB   1 
ATOM   2777 C CG   . ASP A 1 178 ? 99.33494  -3.75077  19.45008 1.000 56.34037  ? 179 ASP A CG   1 
ATOM   2778 O OD1  . ASP A 1 178 ? 98.44926  -4.31530  20.19431 1.000 48.91359  ? 179 ASP A OD1  1 
ATOM   2779 O OD2  . ASP A 1 178 ? 100.56522 -3.90175  19.66181 1.000 55.36867  ? 179 ASP A OD2  1 
ATOM   2780 H H    . ASP A 1 178 ? 97.17025  -4.06218  17.05237 1.000 61.69489  ? 179 ASP A H    1 
ATOM   2781 H HA   . ASP A 1 178 ? 97.11483  -2.33493  19.08408 1.000 64.66051  ? 179 ASP A HA   1 
ATOM   2782 H HB2  . ASP A 1 178 ? 99.21520  -3.27676  17.43968 1.000 57.62502  ? 179 ASP A HB2  1 
ATOM   2783 H HB3  . ASP A 1 178 ? 99.44461  -1.99846  18.35550 1.000 57.62502  ? 179 ASP A HB3  1 
ATOM   2784 N N    . LEU A 1 179 ? 96.22617  -1.16515  16.47152 1.000 56.07615  ? 180 LEU A N    1 
ATOM   2785 C CA   . LEU A 1 179 ? 96.11607  -0.01579  15.56793 1.000 55.99798  ? 180 LEU A CA   1 
ATOM   2786 C C    . LEU A 1 179 ? 95.89473  1.27753   16.34252 1.000 62.84699  ? 180 LEU A C    1 
ATOM   2787 O O    . LEU A 1 179 ? 96.64010  2.25306   16.16372 1.000 54.15966  ? 180 LEU A O    1 
ATOM   2788 C CB   . LEU A 1 179 ? 94.98094  -0.19730  14.56835 1.000 59.49503  ? 180 LEU A CB   1 
ATOM   2789 C CG   . LEU A 1 179 ? 95.29470  -1.19233  13.43864 1.000 57.09439  ? 180 LEU A CG   1 
ATOM   2790 C CD1  . LEU A 1 179 ? 94.05731  -1.59720  12.62470 1.000 49.45053  ? 180 LEU A CD1  1 
ATOM   2791 C CD2  . LEU A 1 179 ? 96.39585  -0.64520  12.50246 1.000 50.14669  ? 180 LEU A CD2  1 
ATOM   2792 H H    . LEU A 1 179 ? 95.60660  -1.75570  16.38792 1.000 67.36265  ? 180 LEU A H    1 
ATOM   2793 H HA   . LEU A 1 179 ? 96.94939  0.03908   15.07450 1.000 67.26884  ? 180 LEU A HA   1 
ATOM   2794 H HB2  . LEU A 1 179 ? 94.20005  -0.52423  15.04187 1.000 71.46531  ? 180 LEU A HB2  1 
ATOM   2795 H HB3  . LEU A 1 179 ? 94.78646  0.66112   14.16070 1.000 71.46531  ? 180 LEU A HB3  1 
ATOM   2796 H HG   . LEU A 1 179 ? 95.61983  -2.00007  13.86615 1.000 68.58453  ? 180 LEU A HG   1 
ATOM   2797 H HD11 . LEU A 1 179 ? 94.30438  -2.29916  12.00252 1.000 59.41190  ? 180 LEU A HD11 1 
ATOM   2798 H HD12 . LEU A 1 179 ? 93.37184  -1.91879  13.23101 1.000 59.41190  ? 180 LEU A HD12 1 
ATOM   2799 H HD13 . LEU A 1 179 ? 93.73220  -0.82347  12.13834 1.000 59.41190  ? 180 LEU A HD13 1 
ATOM   2800 H HD21 . LEU A 1 179 ? 96.41182  -1.17517  11.69019 1.000 60.24729  ? 180 LEU A HD21 1 
ATOM   2801 H HD22 . LEU A 1 179 ? 96.19831  0.28033   12.28971 1.000 60.24729  ? 180 LEU A HD22 1 
ATOM   2802 H HD23 . LEU A 1 179 ? 97.25247  -0.70535  12.95355 1.000 60.24729  ? 180 LEU A HD23 1 
ATOM   2803 N N    . GLU A 1 180 ? 94.87377  1.30065   17.21628 1.000 57.75017  ? 181 GLU A N    1 
ATOM   2804 C CA   . GLU A 1 180 ? 94.58593  2.51734   17.97601 1.000 58.67270  ? 181 GLU A CA   1 
ATOM   2805 C C    . GLU A 1 180 ? 95.75082  2.87550   18.88361 1.000 55.57653  ? 181 GLU A C    1 
ATOM   2806 O O    . GLU A 1 180 ? 95.95936  4.05108   19.18604 1.000 54.11656  ? 181 GLU A O    1 
ATOM   2807 C CB   . GLU A 1 180 ? 93.30156  2.36249   18.76800 1.000 55.20556  ? 181 GLU A CB   1 
ATOM   2808 C CG   . GLU A 1 180 ? 92.07195  2.26634   17.88375 1.000 63.44883  ? 181 GLU A CG   1 
ATOM   2809 C CD   . GLU A 1 180 ? 92.07654  3.30294   16.73208 1.000 73.12875  ? 181 GLU A CD   1 
ATOM   2810 O OE1  . GLU A 1 180 ? 92.25391  4.52393   16.96614 1.000 74.31132  ? 181 GLU A OE1  1 
ATOM   2811 O OE2  . GLU A 1 180 ? 91.92348  2.88778   15.58614 1.000 68.13401  ? 181 GLU A OE2  1 
ATOM   2812 H H    . GLU A 1 180 ? 94.34851  0.63976   17.38038 1.000 69.37148  ? 181 GLU A H    1 
ATOM   2813 H HA   . GLU A 1 180 ? 94.44634  3.25281   17.35917 1.000 70.47850  ? 181 GLU A HA   1 
ATOM   2814 H HB2  . GLU A 1 180 ? 93.35389  1.55194   19.29825 1.000 66.31794  ? 181 GLU A HB2  1 
ATOM   2815 H HB3  . GLU A 1 180 ? 93.19427  3.13226   19.34838 1.000 66.31794  ? 181 GLU A HB3  1 
ATOM   2816 H HG2  . GLU A 1 180 ? 92.03496  1.38081   17.48957 1.000 76.20987  ? 181 GLU A HG2  1 
ATOM   2817 H HG3  . GLU A 1 180 ? 91.28156  2.42229   18.42399 1.000 76.20987  ? 181 GLU A HG3  1 
ATOM   2818 N N    . ALA A 1 181 ? 96.55357  1.87694   19.28688 1.000 53.70971  ? 182 ALA A N    1 
ATOM   2819 C CA   . ALA A 1 181 ? 97.71777  2.14110   20.12362 1.000 49.36182  ? 182 ALA A CA   1 
ATOM   2820 C C    . ALA A 1 181 ? 98.84465  2.80671   19.34364 1.000 49.78123  ? 182 ALA A C    1 
ATOM   2821 O O    . ALA A 1 181 ? 99.63497  3.57140   19.91400 1.000 50.11288  ? 182 ALA A O    1 
ATOM   2822 C CB   . ALA A 1 181 ? 98.20612  0.84435   20.76286 1.000 50.54426  ? 182 ALA A CB   1 
ATOM   2823 H H    . ALA A 1 181 ? 96.44163  1.04773   19.08818 1.000 64.52292  ? 182 ALA A H    1 
ATOM   2824 H HA   . ALA A 1 181 ? 97.45546  2.74767   20.83366 1.000 59.30545  ? 182 ALA A HA   1 
ATOM   2825 H HB1  . ALA A 1 181 ? 98.96467  1.04032   21.33479 1.000 60.72437  ? 182 ALA A HB1  1 
ATOM   2826 H HB2  . ALA A 1 181 ? 97.48645  0.46050   21.28788 1.000 60.72437  ? 182 ALA A HB2  1 
ATOM   2827 H HB3  . ALA A 1 181 ? 98.47043  0.22715   20.06279 1.000 60.72437  ? 182 ALA A HB3  1 
ATOM   2828 N N    . MET A 1 182 ? 98.96263  2.51817   18.06058 1.000 53.23710  ? 183 MET A N    1 
ATOM   2829 C CA   . MET A 1 182 ? 100.03031 3.07802   17.24933 1.000 53.44969  ? 183 MET A CA   1 
ATOM   2830 C C    . MET A 1 182 ? 99.56296  4.25057   16.38942 1.000 53.92261  ? 183 MET A C    1 
ATOM   2831 O O    . MET A 1 182 ? 100.39981 4.91603   15.76304 1.000 51.42381  ? 183 MET A O    1 
ATOM   2832 C CB   . MET A 1 182 ? 100.60806 2.00393   16.31247 1.000 52.14404  ? 183 MET A CB   1 
ATOM   2833 C CG   . MET A 1 182 ? 100.99292 0.71813   17.04501 1.000 52.96486  ? 183 MET A CG   1 
ATOM   2834 S SD   . MET A 1 182 ? 102.33142 0.99105   18.20859 1.000 64.55344  ? 183 MET A SD   1 
ATOM   2835 C CE   . MET A 1 182 ? 103.70316 1.32836   17.20725 1.000 57.01477  ? 183 MET A CE   1 
ATOM   2836 H H    . MET A 1 182 ? 98.43197  1.99535   17.63086 1.000 63.95578  ? 183 MET A H    1 
ATOM   2837 H HA   . MET A 1 182 ? 100.73662 3.37363   17.84485 1.000 64.21089  ? 183 MET A HA   1 
ATOM   2838 H HB2  . MET A 1 182 ? 99.94320  1.77960   15.64274 1.000 62.64412  ? 183 MET A HB2  1 
ATOM   2839 H HB3  . MET A 1 182 ? 101.40473 2.35482   15.88457 1.000 62.64412  ? 183 MET A HB3  1 
ATOM   2840 H HG2  . MET A 1 182 ? 100.22481 0.38796   17.53684 1.000 63.62910  ? 183 MET A HG2  1 
ATOM   2841 H HG3  . MET A 1 182 ? 101.28240 0.05579   16.39817 1.000 63.62910  ? 183 MET A HG3  1 
ATOM   2842 H HE1  . MET A 1 182 ? 104.49946 1.35373   17.76057 1.000 68.48899  ? 183 MET A HE1  1 
ATOM   2843 H HE2  . MET A 1 182 ? 103.78634 0.62953   16.53971 1.000 68.48899  ? 183 MET A HE2  1 
ATOM   2844 H HE3  . MET A 1 182 ? 103.57423 2.18639   16.77359 1.000 68.48899  ? 183 MET A HE3  1 
ATOM   2845 N N    . ARG A 1 183 ? 98.25600  4.50191   16.31737 1.000 48.83486  ? 184 ARG A N    1 
ATOM   2846 C CA   . ARG A 1 183 ? 97.78224  5.61581   15.51691 1.000 58.32838  ? 184 ARG A CA   1 
ATOM   2847 C C    . ARG A 1 183 ? 98.40102  6.92622   16.01428 1.000 65.66429  ? 184 ARG A C    1 
ATOM   2848 O O    . ARG A 1 183 ? 98.48244  7.17447   17.22995 1.000 63.77765  ? 184 ARG A O    1 
ATOM   2849 C CB   . ARG A 1 183 ? 96.26095  5.72702   15.57362 1.000 58.80268  ? 184 ARG A CB   1 
ATOM   2850 C CG   . ARG A 1 183 ? 95.78440  6.86865   14.71845 1.000 57.79370  ? 184 ARG A CG   1 
ATOM   2851 C CD   . ARG A 1 183 ? 94.29476  7.06180   14.83523 1.000 60.66226  ? 184 ARG A CD   1 
ATOM   2852 N NE   . ARG A 1 183 ? 93.56862  5.86753   14.43026 1.000 62.70580  ? 184 ARG A NE   1 
ATOM   2853 C CZ   . ARG A 1 183 ? 93.30936  5.52188   13.16890 1.000 63.68837  ? 184 ARG A CZ   1 
ATOM   2854 N NH1  . ARG A 1 183 ? 93.75476  6.23336   12.13484 1.000 63.72176  ? 184 ARG A NH1  1 
ATOM   2855 N NH2  . ARG A 1 183 ? 92.55827  4.45688   12.93530 1.000 74.73480  ? 184 ARG A NH2  1 
ATOM   2856 H H    . ARG A 1 183 ? 97.64113  4.05060   16.71467 1.000 58.67310  ? 184 ARG A H    1 
ATOM   2857 H HA   . ARG A 1 183 ? 98.04649  5.46892   14.59522 1.000 70.06533  ? 184 ARG A HA   1 
ATOM   2858 H HB2  . ARG A 1 183 ? 95.86319  4.90595   15.24419 1.000 70.63448  ? 184 ARG A HB2  1 
ATOM   2859 H HB3  . ARG A 1 183 ? 95.98132  5.88735   16.48850 1.000 70.63448  ? 184 ARG A HB3  1 
ATOM   2860 H HG2  . ARG A 1 183 ? 96.22108  7.68692   15.00243 1.000 69.42371  ? 184 ARG A HG2  1 
ATOM   2861 H HG3  . ARG A 1 183 ? 95.99607  6.68468   13.78987 1.000 69.42371  ? 184 ARG A HG3  1 
ATOM   2862 H HD2  . ARG A 1 183 ? 94.06786  7.25870   15.75753 1.000 72.86598  ? 184 ARG A HD2  1 
ATOM   2863 H HD3  . ARG A 1 183 ? 94.02014  7.79474   14.26228 1.000 72.86598  ? 184 ARG A HD3  1 
ATOM   2864 H HE   . ARG A 1 183 ? 93.28518  5.34499   15.05172 1.000 75.31823  ? 184 ARG A HE   1 
ATOM   2865 H HH11 . ARG A 1 183 ? 94.22555  6.94022   12.27014 1.000 76.53738  ? 184 ARG A HH11 1 
ATOM   2866 H HH12 . ARG A 1 183 ? 93.57159  5.98590   11.33184 1.000 76.53738  ? 184 ARG A HH12 1 
ATOM   2867 H HH21 . ARG A 1 183 ? 92.24522  3.99894   13.59249 1.000 89.75303  ? 184 ARG A HH21 1 
ATOM   2868 H HH22 . ARG A 1 183 ? 92.38346  4.22304   12.12638 1.000 89.75303  ? 184 ARG A HH22 1 
ATOM   2869 N N    . PRO A 1 184 ? 98.86107  7.77929   15.10758 1.000 66.58187  ? 185 PRO A N    1 
ATOM   2870 C CA   . PRO A 1 184 ? 99.41149  9.07295   15.53536 1.000 70.09359  ? 185 PRO A CA   1 
ATOM   2871 C C    . PRO A 1 184 ? 98.32142  10.04450  15.94689 1.000 71.88760  ? 185 PRO A C    1 
ATOM   2872 O O    . PRO A 1 184 ? 97.23904  10.08366  15.35529 1.000 67.38210  ? 185 PRO A O    1 
ATOM   2873 C CB   . PRO A 1 184 ? 100.17192 9.56380   14.29965 1.000 67.08296  ? 185 PRO A CB   1 
ATOM   2874 C CG   . PRO A 1 184 ? 100.51016 8.31922   13.54587 1.000 63.47760  ? 185 PRO A CG   1 
ATOM   2875 C CD   . PRO A 1 184 ? 99.29779  7.42577   13.74481 1.000 65.62882  ? 185 PRO A CD   1 
ATOM   2876 H HA   . PRO A 1 184 ? 100.02873 8.95371   16.27407 1.000 84.18357  ? 185 PRO A HA   1 
ATOM   2877 H HB2  . PRO A 1 184 ? 99.60519  10.14779  13.77177 1.000 80.57082  ? 185 PRO A HB2  1 
ATOM   2878 H HB3  . PRO A 1 184 ? 100.97465 10.03636  14.57025 1.000 80.57082  ? 185 PRO A HB3  1 
ATOM   2879 H HG2  . PRO A 1 184 ? 100.64451 8.52300   12.60708 1.000 76.24438  ? 185 PRO A HG2  1 
ATOM   2880 H HG3  . PRO A 1 184 ? 101.30949 7.91181   13.91461 1.000 76.24438  ? 185 PRO A HG3  1 
ATOM   2881 H HD2  . PRO A 1 184 ? 98.60666  7.62671   13.09453 1.000 78.82585  ? 185 PRO A HD2  1 
ATOM   2882 H HD3  . PRO A 1 184 ? 99.54286  6.48886   13.68972 1.000 78.82585  ? 185 PRO A HD3  1 
ATOM   2883 N N    . ARG A 1 185 ? 98.62787  10.81687  16.99403 1.000 85.55469  ? 186 ARG A N    1 
ATOM   2884 C CA   . ARG A 1 185 ? 97.70081  11.73772  17.65000 1.000 85.58795  ? 186 ARG A CA   1 
ATOM   2885 C C    . ARG A 1 185 ? 98.36061  13.11177  17.67329 1.000 90.28720  ? 186 ARG A C    1 
ATOM   2886 O O    . ARG A 1 185 ? 99.45761  13.27040  18.21968 1.000 82.32555  ? 186 ARG A O    1 
ATOM   2887 C CB   . ARG A 1 185 ? 97.37383  11.24916  19.05705 1.000 85.16827  ? 186 ARG A CB   1 
ATOM   2888 C CG   . ARG A 1 185 ? 97.12777  9.73830   19.18206 1.000 71.44388  ? 186 ARG A CG   1 
ATOM   2889 C CD   . ARG A 1 185 ? 95.64351  9.40607   19.07715 1.000 60.96195  ? 186 ARG A CD   1 
ATOM   2890 N NE   . ARG A 1 185 ? 95.38966  7.97913   19.22123 1.000 55.93663  ? 186 ARG A NE   1 
ATOM   2891 C CZ   . ARG A 1 185 ? 94.22283  7.41048   18.95309 1.000 62.18069  ? 186 ARG A CZ   1 
ATOM   2892 N NH1  . ARG A 1 185 ? 93.17212  8.13421   18.58749 1.000 54.41445  ? 186 ARG A NH1  1 
ATOM   2893 N NH2  . ARG A 1 185 ? 94.11306  6.08085   19.02728 1.000 63.75391  ? 186 ARG A NH2  1 
ATOM   2894 H H    . ARG A 1 185 ? 99.40658  10.82365  17.35895 1.000 102.73689 ? 186 ARG A H    1 
ATOM   2895 H HA   . ARG A 1 185 ? 96.86807  11.80704  17.15742 1.000 102.77681 ? 186 ARG A HA   1 
ATOM   2896 H HB2  . ARG A 1 185 ? 98.11731  11.47131  19.63910 1.000 102.27319 ? 186 ARG A HB2  1 
ATOM   2897 H HB3  . ARG A 1 185 ? 96.56987  11.70015  19.35896 1.000 102.27319 ? 186 ARG A HB3  1 
ATOM   2898 H HG2  . ARG A 1 185 ? 97.59525  9.27611   18.46881 1.000 85.80392  ? 186 ARG A HG2  1 
ATOM   2899 H HG3  . ARG A 1 185 ? 97.44943  9.43018   20.04374 1.000 85.80392  ? 186 ARG A HG3  1 
ATOM   2900 H HD2  . ARG A 1 185 ? 95.16231  9.87132   19.77921 1.000 73.22560  ? 186 ARG A HD2  1 
ATOM   2901 H HD3  . ARG A 1 185 ? 95.31493  9.68556   18.20834 1.000 73.22560  ? 186 ARG A HD3  1 
ATOM   2902 H HE   . ARG A 1 185 ? 96.03240  7.47783   19.49543 1.000 67.19523  ? 186 ARG A HE   1 
ATOM   2903 H HH11 . ARG A 1 185 ? 93.24086  8.98886   18.52078 1.000 65.36860  ? 186 ARG A HH11 1 
ATOM   2904 H HH12 . ARG A 1 185 ? 92.42253  7.74852   18.41728 1.000 65.36860  ? 186 ARG A HH12 1 
ATOM   2905 H HH21 . ARG A 1 185 ? 94.79472  5.60470   19.24688 1.000 76.57596  ? 186 ARG A HH21 1 
ATOM   2906 H HH22 . ARG A 1 185 ? 93.36076  5.70124   18.85541 1.000 76.57596  ? 186 ARG A HH22 1 
ATOM   2907 N N    . GLY A 1 186 ? 97.72083  14.08785  17.03947 1.000 101.44502 ? 187 GLY A N    1 
ATOM   2908 C CA   . GLY A 1 186 ? 98.41769  15.29756  16.62972 1.000 116.65476 ? 187 GLY A CA   1 
ATOM   2909 C C    . GLY A 1 186 ? 98.13300  16.51775  17.46535 1.000 124.15584 ? 187 GLY A C    1 
ATOM   2910 O O    . GLY A 1 186 ? 97.19268  16.51822  18.24859 1.000 114.87510 ? 187 GLY A O    1 
ATOM   2911 H H    . GLY A 1 186 ? 96.88534  14.07242  16.83619 1.000 121.80529 ? 187 GLY A H    1 
ATOM   2912 H HA2  . GLY A 1 186 ? 99.37278  15.13239  16.66735 1.000 140.05698 ? 187 GLY A HA2  1 
ATOM   2913 H HA3  . GLY A 1 186 ? 98.16860  15.50353  15.71515 1.000 140.05698 ? 187 GLY A HA3  1 
HETATM 2914 O O    . HOH B 2 .   ? 88.50715  -53.88792 7.39548  1.000 65.08677  ? 201 HOH A O    1 
HETATM 2915 O O    . HOH B 2 .   ? 78.73588  -15.13961 -2.16068 1.000 61.77999  ? 202 HOH A O    1 
HETATM 2916 O O    . HOH B 2 .   ? 83.75385  -25.92804 15.11339 1.000 67.08274  ? 203 HOH A O    1 
HETATM 2917 O O    . HOH B 2 .   ? 90.36753  -43.91331 6.63357  1.000 58.77133  ? 204 HOH A O    1 
HETATM 2918 O O    . HOH B 2 .   ? 94.64981  -42.98117 3.05422  1.000 52.65344  ? 205 HOH A O    1 
HETATM 2919 O O    . HOH B 2 .   ? 104.05727 -24.44852 20.15071 1.000 61.95761  ? 206 HOH A O    1 
HETATM 2920 O O    . HOH B 2 .   ? 98.25789  -11.15686 3.49617  1.000 52.66295  ? 207 HOH A O    1 
HETATM 2921 O O    . HOH B 2 .   ? 75.49823  -7.06218  2.14353  1.000 69.62903  ? 208 HOH A O    1 
HETATM 2922 O O    . HOH B 2 .   ? 96.21138  -3.93139  21.35843 1.000 53.17290  ? 209 HOH A O    1 
HETATM 2923 O O    . HOH B 2 .   ? 94.64569  -12.20481 -1.41135 1.000 61.15770  ? 210 HOH A O    1 
HETATM 2924 O O    . HOH B 2 .   ? 102.82526 2.47939   1.73308  1.000 55.16128  ? 211 HOH A O    1 
HETATM 2925 O O    . HOH B 2 .   ? 102.12369 -7.04301  6.99412  1.000 55.89269  ? 212 HOH A O    1 
HETATM 2926 O O    . HOH B 2 .   ? 77.51611  -17.20658 14.27696 1.000 58.12222  ? 213 HOH A O    1 
HETATM 2927 O O    . HOH B 2 .   ? 104.29539 -31.56863 26.40305 1.000 64.34502  ? 214 HOH A O    1 
HETATM 2928 O O    . HOH B 2 .   ? 105.53684 -44.71136 21.75547 1.000 69.11200  ? 215 HOH A O    1 
HETATM 2929 O O    . HOH B 2 .   ? 102.59019 0.55323   4.20926  1.000 59.83498  ? 216 HOH A O    1 
HETATM 2930 O O    . HOH B 2 .   ? 97.64522  6.15559   19.53192 1.000 47.82011  ? 217 HOH A O    1 
HETATM 2931 O O    . HOH B 2 .   ? 91.11167  -44.35798 3.19907  1.000 58.58712  ? 218 HOH A O    1 
HETATM 2932 O O    . HOH B 2 .   ? 105.34396 -10.15477 11.57217 1.000 56.23051  ? 219 HOH A O    1 
HETATM 2933 O O    . HOH B 2 .   ? 94.67455  -0.82781  19.65176 1.000 57.24181  ? 220 HOH A O    1 
HETATM 2934 O O    . HOH B 2 .   ? 102.58802 5.27324   11.53844 1.000 62.39914  ? 221 HOH A O    1 
HETATM 2935 O O    . HOH B 2 .   ? 93.41095  -26.45817 11.61204 1.000 51.10679  ? 222 HOH A O    1 
HETATM 2936 O O    . HOH B 2 .   ? 102.90110 6.07913   0.91173  1.000 56.79612  ? 223 HOH A O    1 
HETATM 2937 O O    . HOH B 2 .   ? 86.40427  -10.27982 8.16382  1.000 53.34924  ? 224 HOH A O    1 
HETATM 2938 O O    . HOH B 2 .   ? 95.54897  -12.50701 4.34639  1.000 54.96452  ? 225 HOH A O    1 
HETATM 2939 O O    . HOH B 2 .   ? 94.87217  -32.01456 19.48050 1.000 54.93140  ? 226 HOH A O    1 
HETATM 2940 O O    . HOH B 2 .   ? 88.01613  -29.99409 17.87645 1.000 51.58620  ? 227 HOH A O    1 
HETATM 2941 O O    . HOH B 2 .   ? 100.02123 7.44228   0.41961  1.000 54.99486  ? 228 HOH A O    1 
HETATM 2942 O O    . HOH B 2 .   ? 80.22303  -50.22022 8.47367  1.000 73.94629  ? 229 HOH A O    1 
HETATM 2943 O O    . HOH B 2 .   ? 85.95461  -16.01813 17.80571 1.000 54.74438  ? 230 HOH A O    1 
HETATM 2944 O O    . HOH B 2 .   ? 99.370    -28.846   30.445   1.000 56.19160  ? 231 HOH A O    1 
HETATM 2945 O O    . HOH B 2 .   ? 92.46866  -0.98164  17.10391 1.000 66.05233  ? 232 HOH A O    1 
HETATM 2946 O O    . HOH B 2 .   ? 103.43005 -39.50859 16.68415 1.000 61.86604  ? 233 HOH A O    1 
HETATM 2947 O O    . HOH B 2 .   ? 82.20646  -12.04728 17.40705 1.000 59.69659  ? 234 HOH A O    1 
HETATM 2948 O O    . HOH B 2 .   ? 83.11024  -14.85426 20.72742 1.000 57.54677  ? 235 HOH A O    1 
HETATM 2949 O O    . HOH B 2 .   ? 96.61794  -21.48217 7.51718  1.000 50.92042  ? 236 HOH A O    1 
HETATM 2950 O O    . HOH B 2 .   ? 84.16721  -24.02510 16.67738 1.000 56.45764  ? 237 HOH A O    1 
HETATM 2951 O O    . HOH B 2 .   ? 95.12210  -52.89027 21.99416 1.000 73.73083  ? 238 HOH A O    1 
HETATM 2952 O O    . HOH B 2 .   ? 90.89299  -9.39370  9.97047  1.000 52.89979  ? 239 HOH A O    1 
HETATM 2953 O O    . HOH B 2 .   ? 100.69147 -10.12205 17.12804 1.000 53.27689  ? 240 HOH A O    1 
HETATM 2954 O O    . HOH B 2 .   ? 102.33235 -3.10432  17.48980 1.000 47.36130  ? 241 HOH A O    1 
HETATM 2955 O O    . HOH B 2 .   ? 83.76091  -20.66930 20.28333 1.000 49.42841  ? 242 HOH A O    1 
HETATM 2956 O O    . HOH B 2 .   ? 101.56631 -21.76742 12.21368 1.000 57.76551  ? 243 HOH A O    1 
HETATM 2957 O O    . HOH B 2 .   ? 86.92379  -26.07678 7.84269  1.000 63.75439  ? 244 HOH A O    1 
HETATM 2958 O O    . HOH B 2 .   ? 91.67789  -10.01973 5.83545  1.000 54.00050  ? 245 HOH A O    1 
HETATM 2959 O O    . HOH B 2 .   ? 101.15008 -3.31530  1.78358  1.000 59.56108  ? 246 HOH A O    1 
HETATM 2960 O O    . HOH B 2 .   ? 96.28851  -36.76772 0.75864  1.000 58.59863  ? 247 HOH A O    1 
HETATM 2961 O O    . HOH B 2 .   ? 84.44551  -27.19713 11.73656 1.000 58.10044  ? 248 HOH A O    1 
HETATM 2962 O O    . HOH B 2 .   ? 103.72454 -5.68629  9.09104  1.000 53.34255  ? 249 HOH A O    1 
HETATM 2963 O O    . HOH B 2 .   ? 92.61886  -3.36518  3.60704  1.000 63.34338  ? 250 HOH A O    1 
HETATM 2964 O O    . HOH B 2 .   ? 91.60063  -28.76752 11.47784 1.000 61.63301  ? 251 HOH A O    1 
HETATM 2965 O O    . HOH B 2 .   ? 80.16652  -13.24481 19.02910 1.000 60.04200  ? 252 HOH A O    1 
HETATM 2966 O O    . HOH B 2 .   ? 86.58530  -27.53021 10.41614 1.000 57.91601  ? 253 HOH A O    1 
HETATM 2967 O O    . HOH B 2 .   ? 88.96879  -9.85893  7.81288  1.000 63.58646  ? 254 HOH A O    1 
HETATM 2968 O O    . HOH B 2 .   ? 98.79410  -36.54929 0.68910  1.000 60.23412  ? 255 HOH A O    1 
HETATM 2969 O O    . HOH B 2 .   ? 83.32909  -23.17576 19.10556 1.000 55.65583  ? 256 HOH A O    1 
HETATM 2970 O O    . HOH B 2 .   ? 94.19450  -54.38322 20.66150 0.16  54.08702  ? 257 HOH A O    1 
# 
