data_9MTY
# 
_entry.id   9MTY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MTY         pdb_00009mty 10.2210/pdb9mty/pdb 
WWPDB D_1000291833 ?            ?                   
EMDB  EMD-48616    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-03-05 ? 
2  'EM metadata'     1 0 2025-03-05 ? 
3  FSC               1 0 2025-03-05 ? 
4  'Half map'        1 0 2025-03-05 1 
5  'Half map'        1 0 2025-03-05 2 
6  Image             1 0 2025-03-05 ? 
7  Mask              1 0 2025-03-05 1 
8  'Primary map'     1 0 2025-03-05 ? 
9  'Structure model' 1 1 2025-04-16 ? 
10 'Structure model' 1 2 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 Mask              repository 'Initial release' ? ? 
8 8 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'     
2 9  'Structure model' 'Database references' 
3 10 'Structure model' 'Data collection'     
4 10 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 10 'Structure model' citation        
5 10 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_ASTM'         
4  9  'Structure model' '_citation.journal_id_CSD'          
5  9  'Structure model' '_citation.journal_id_ISSN'         
6  9  'Structure model' '_citation.page_first'              
7  9  'Structure model' '_citation.page_last'               
8  9  'Structure model' '_citation.pdbx_database_id_DOI'    
9  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
10 9  'Structure model' '_citation.title'                   
11 9  'Structure model' '_citation.year'                    
12 9  'Structure model' '_citation_author.identifier_ORCID' 
13 9  'Structure model' '_em_admin.last_update'             
14 10 'Structure model' '_citation.journal_volume'          
15 10 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MTY 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage' 
_pdbx_database_related.db_id          EMD-48616 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhang@broadinstitute.org 
_pdbx_contact_author.name_first         Feng 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0178-7995 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wilkinson, M.E.' 1 0000-0003-4738-9503 
'Zhang, F.'       2 0000-0003-0178-7995 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Science 
_citation.journal_id_ASTM           SCIEAS 
_citation.journal_id_CSD            0038 
_citation.journal_id_ISSN           1095-9203 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            388 
_citation.language                  ? 
_citation.page_first                eadv9789 
_citation.page_last                 eadv9789 
_citation.title                     
'TIGR-Tas: A family of modular RNA-guided DNA-targeting systems in prokaryotes and their viruses.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1126/science.adv9789 
_citation.pdbx_database_id_PubMed   40014690 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Faure, G.'           1  0000-0001-9537-2277 
primary 'Saito, M.'           2  0000-0001-8619-5176 
primary 'Wilkinson, M.E.'     3  0000-0003-4738-9503 
primary 'Quinones-Olvera, N.' 4  0000-0002-4612-6819 
primary 'Xu, P.'              5  0000-0003-3590-4037 
primary 'Flam-Shepherd, D.'   6  ?                   
primary 'Kim, S.'             7  ?                   
primary 'Reddy, N.'           8  0000-0001-5912-6925 
primary 'Zhu, S.'             9  0009-0001-2677-8262 
primary 'Evgeniou, L.'        10 0009-0005-5707-2413 
primary 'Koonin, E.V.'        11 0000-0003-3943-8299 
primary 'Macrae, R.K.'        12 0000-0002-7850-9056 
primary 'Zhang, F.'           13 0000-0003-0178-7995 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Transposase IS116/IS110/IS902 C-terminal domain-containing protein' 38276.855 2 ? ? ? ? 
2 polymer     man tigRNA                                                               11484.882 1 ? ? ? ? 
3 polymer     syn 
;Target DNA, spacer A targeted strand, 5' of cut
;
10537.799 1 ? ? ? ? 
4 polymer     syn 
;Target DNA, spacer A targeted strand, 3' of cut
;
7999.197  1 ? ? ? ? 
5 polymer     syn 
;Target DNA, spacer B targeted strand, 5' of cut
;
10392.662 1 ? ? ? ? 
6 polymer     syn 
;Target DNA, spacer B targeted strand, 3' of cut
;
7961.164  1 ? ? ? ? 
7 non-polymer syn 'MAGNESIUM ION'                                                      24.305    4 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MDNDITILAVDWSHEERKLAIFDGKKIRKKLPEPSSDVIIVAENIPQKYAAPFIEVGAKVLRCSTNATADARKNYQKKVD
AAFAKNDENDSKVIWALYQTHPELFREMKLEPPLSSYYAIFKDYQEVRIRTGNRLYSDRTDAMEEFFKIVKKGEHELKKA
VDKELENHPVYTQWLQHIKGIGPVVAGGLISLIGDIDRFDSVSKLWAYAGYSVDNGKVQKRKKGVASNWKNKIRTHCYNI
VDSFIKQRTSVYRELYDAEKARQRPKVESDGHAHNRAVRKVAKVFLQHYWVVSRELAGFSVSKPWILEHGGHVDYIKPPH
WNKVEIKPCKP
;
;MDNDITILAVDWSHEERKLAIFDGKKIRKKLPEPSSDVIIVAENIPQKYAAPFIEVGAKVLRCSTNATADARKNYQKKVD
AAFAKNDENDSKVIWALYQTHPELFREMKLEPPLSSYYAIFKDYQEVRIRTGNRLYSDRTDAMEEFFKIVKKGEHELKKA
VDKELENHPVYTQWLQHIKGIGPVVAGGLISLIGDIDRFDSVSKLWAYAGYSVDNGKVQKRKKGVASNWKNKIRTHCYNI
VDSFIKQRTSVYRELYDAEKARQRPKVESDGHAHNRAVRKVAKVFLQHYWVVSRELAGFSVSKPWILEHGGHVDYIKPPH
WNKVEIKPCKP
;
A,B ? 
2 polyribonucleotide      no no AGCCAUGCAAGCCCUGAAACCCAUUGCCUUAGUGCG AGCCAUGCAAGCCCUGAAACCCAUUGCCUUAGUGCG C   ? 
3 polydeoxyribonucleotide no no 
;(DT)(DC)(DA)(DG)(DC)(DG)(DT)(DT)(DA)(DA)(DA)(DA)(DA)(DA)(DT)(DT)(DG)(DA)(DT)(DG)
(DA)(DT)(DT)(DG)(DC)(DC)(DT)(DT)(DA)(DG)(DG)(DG)(DG)(DC)
;
TCAGCGTTAAAAAATTGATGATTGCCTTAGGGGC D   ? 
4 polydeoxyribonucleotide no no 
;(DT)(DT)(DG)(DC)(DA)(DT)(DC)(DG)(DA)(DA)(DA)(DC)(DC)(DA)(DC)(DA)(DG)(DC)(DC)(DA)
(DA)(DG)(DG)(DG)(DA)(DA)
;
TTGCATCGAAACCACAGCCAAGGGAA F   ? 
5 polydeoxyribonucleotide no no 
;(DT)(DT)(DC)(DC)(DC)(DT)(DT)(DG)(DG)(DC)(DT)(DG)(DT)(DG)(DG)(DT)(DT)(DT)(DC)(DG)
(DA)(DT)(DG)(DC)(DA)(DA)(DG)(DC)(DC)(DC)(DC)(DT)(DA)(DA)
;
TTCCCTTGGCTGTGGTTTCGATGCAAGCCCCTAA E   ? 
6 polydeoxyribonucleotide no no 
;(DG)(DG)(DC)(DA)(DA)(DT)(DC)(DA)(DT)(DC)(DA)(DA)(DT)(DT)(DT)(DT)(DT)(DT)(DA)(DA)
(DC)(DG)(DC)(DT)(DG)(DA)
;
GGCAATCATCAATTTTTTAACGCTGA G   ? 
# 
_pdbx_entity_nonpoly.entity_id   7 
_pdbx_entity_nonpoly.name        'MAGNESIUM ION' 
_pdbx_entity_nonpoly.comp_id     MG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   ASN n 
1 4   ASP n 
1 5   ILE n 
1 6   THR n 
1 7   ILE n 
1 8   LEU n 
1 9   ALA n 
1 10  VAL n 
1 11  ASP n 
1 12  TRP n 
1 13  SER n 
1 14  HIS n 
1 15  GLU n 
1 16  GLU n 
1 17  ARG n 
1 18  LYS n 
1 19  LEU n 
1 20  ALA n 
1 21  ILE n 
1 22  PHE n 
1 23  ASP n 
1 24  GLY n 
1 25  LYS n 
1 26  LYS n 
1 27  ILE n 
1 28  ARG n 
1 29  LYS n 
1 30  LYS n 
1 31  LEU n 
1 32  PRO n 
1 33  GLU n 
1 34  PRO n 
1 35  SER n 
1 36  SER n 
1 37  ASP n 
1 38  VAL n 
1 39  ILE n 
1 40  ILE n 
1 41  VAL n 
1 42  ALA n 
1 43  GLU n 
1 44  ASN n 
1 45  ILE n 
1 46  PRO n 
1 47  GLN n 
1 48  LYS n 
1 49  TYR n 
1 50  ALA n 
1 51  ALA n 
1 52  PRO n 
1 53  PHE n 
1 54  ILE n 
1 55  GLU n 
1 56  VAL n 
1 57  GLY n 
1 58  ALA n 
1 59  LYS n 
1 60  VAL n 
1 61  LEU n 
1 62  ARG n 
1 63  CYS n 
1 64  SER n 
1 65  THR n 
1 66  ASN n 
1 67  ALA n 
1 68  THR n 
1 69  ALA n 
1 70  ASP n 
1 71  ALA n 
1 72  ARG n 
1 73  LYS n 
1 74  ASN n 
1 75  TYR n 
1 76  GLN n 
1 77  LYS n 
1 78  LYS n 
1 79  VAL n 
1 80  ASP n 
1 81  ALA n 
1 82  ALA n 
1 83  PHE n 
1 84  ALA n 
1 85  LYS n 
1 86  ASN n 
1 87  ASP n 
1 88  GLU n 
1 89  ASN n 
1 90  ASP n 
1 91  SER n 
1 92  LYS n 
1 93  VAL n 
1 94  ILE n 
1 95  TRP n 
1 96  ALA n 
1 97  LEU n 
1 98  TYR n 
1 99  GLN n 
1 100 THR n 
1 101 HIS n 
1 102 PRO n 
1 103 GLU n 
1 104 LEU n 
1 105 PHE n 
1 106 ARG n 
1 107 GLU n 
1 108 MET n 
1 109 LYS n 
1 110 LEU n 
1 111 GLU n 
1 112 PRO n 
1 113 PRO n 
1 114 LEU n 
1 115 SER n 
1 116 SER n 
1 117 TYR n 
1 118 TYR n 
1 119 ALA n 
1 120 ILE n 
1 121 PHE n 
1 122 LYS n 
1 123 ASP n 
1 124 TYR n 
1 125 GLN n 
1 126 GLU n 
1 127 VAL n 
1 128 ARG n 
1 129 ILE n 
1 130 ARG n 
1 131 THR n 
1 132 GLY n 
1 133 ASN n 
1 134 ARG n 
1 135 LEU n 
1 136 TYR n 
1 137 SER n 
1 138 ASP n 
1 139 ARG n 
1 140 THR n 
1 141 ASP n 
1 142 ALA n 
1 143 MET n 
1 144 GLU n 
1 145 GLU n 
1 146 PHE n 
1 147 PHE n 
1 148 LYS n 
1 149 ILE n 
1 150 VAL n 
1 151 LYS n 
1 152 LYS n 
1 153 GLY n 
1 154 GLU n 
1 155 HIS n 
1 156 GLU n 
1 157 LEU n 
1 158 LYS n 
1 159 LYS n 
1 160 ALA n 
1 161 VAL n 
1 162 ASP n 
1 163 LYS n 
1 164 GLU n 
1 165 LEU n 
1 166 GLU n 
1 167 ASN n 
1 168 HIS n 
1 169 PRO n 
1 170 VAL n 
1 171 TYR n 
1 172 THR n 
1 173 GLN n 
1 174 TRP n 
1 175 LEU n 
1 176 GLN n 
1 177 HIS n 
1 178 ILE n 
1 179 LYS n 
1 180 GLY n 
1 181 ILE n 
1 182 GLY n 
1 183 PRO n 
1 184 VAL n 
1 185 VAL n 
1 186 ALA n 
1 187 GLY n 
1 188 GLY n 
1 189 LEU n 
1 190 ILE n 
1 191 SER n 
1 192 LEU n 
1 193 ILE n 
1 194 GLY n 
1 195 ASP n 
1 196 ILE n 
1 197 ASP n 
1 198 ARG n 
1 199 PHE n 
1 200 ASP n 
1 201 SER n 
1 202 VAL n 
1 203 SER n 
1 204 LYS n 
1 205 LEU n 
1 206 TRP n 
1 207 ALA n 
1 208 TYR n 
1 209 ALA n 
1 210 GLY n 
1 211 TYR n 
1 212 SER n 
1 213 VAL n 
1 214 ASP n 
1 215 ASN n 
1 216 GLY n 
1 217 LYS n 
1 218 VAL n 
1 219 GLN n 
1 220 LYS n 
1 221 ARG n 
1 222 LYS n 
1 223 LYS n 
1 224 GLY n 
1 225 VAL n 
1 226 ALA n 
1 227 SER n 
1 228 ASN n 
1 229 TRP n 
1 230 LYS n 
1 231 ASN n 
1 232 LYS n 
1 233 ILE n 
1 234 ARG n 
1 235 THR n 
1 236 HIS n 
1 237 CYS n 
1 238 TYR n 
1 239 ASN n 
1 240 ILE n 
1 241 VAL n 
1 242 ASP n 
1 243 SER n 
1 244 PHE n 
1 245 ILE n 
1 246 LYS n 
1 247 GLN n 
1 248 ARG n 
1 249 THR n 
1 250 SER n 
1 251 VAL n 
1 252 TYR n 
1 253 ARG n 
1 254 GLU n 
1 255 LEU n 
1 256 TYR n 
1 257 ASP n 
1 258 ALA n 
1 259 GLU n 
1 260 LYS n 
1 261 ALA n 
1 262 ARG n 
1 263 GLN n 
1 264 ARG n 
1 265 PRO n 
1 266 LYS n 
1 267 VAL n 
1 268 GLU n 
1 269 SER n 
1 270 ASP n 
1 271 GLY n 
1 272 HIS n 
1 273 ALA n 
1 274 HIS n 
1 275 ASN n 
1 276 ARG n 
1 277 ALA n 
1 278 VAL n 
1 279 ARG n 
1 280 LYS n 
1 281 VAL n 
1 282 ALA n 
1 283 LYS n 
1 284 VAL n 
1 285 PHE n 
1 286 LEU n 
1 287 GLN n 
1 288 HIS n 
1 289 TYR n 
1 290 TRP n 
1 291 VAL n 
1 292 VAL n 
1 293 SER n 
1 294 ARG n 
1 295 GLU n 
1 296 LEU n 
1 297 ALA n 
1 298 GLY n 
1 299 PHE n 
1 300 SER n 
1 301 VAL n 
1 302 SER n 
1 303 LYS n 
1 304 PRO n 
1 305 TRP n 
1 306 ILE n 
1 307 LEU n 
1 308 GLU n 
1 309 HIS n 
1 310 GLY n 
1 311 GLY n 
1 312 HIS n 
1 313 VAL n 
1 314 ASP n 
1 315 TYR n 
1 316 ILE n 
1 317 LYS n 
1 318 PRO n 
1 319 PRO n 
1 320 HIS n 
1 321 TRP n 
1 322 ASN n 
1 323 LYS n 
1 324 VAL n 
1 325 GLU n 
1 326 ILE n 
1 327 LYS n 
1 328 PRO n 
1 329 CYS n 
1 330 LYS n 
1 331 PRO n 
2 1   A   n 
2 2   G   n 
2 3   C   n 
2 4   C   n 
2 5   A   n 
2 6   U   n 
2 7   G   n 
2 8   C   n 
2 9   A   n 
2 10  A   n 
2 11  G   n 
2 12  C   n 
2 13  C   n 
2 14  C   n 
2 15  U   n 
2 16  G   n 
2 17  A   n 
2 18  A   n 
2 19  A   n 
2 20  C   n 
2 21  C   n 
2 22  C   n 
2 23  A   n 
2 24  U   n 
2 25  U   n 
2 26  G   n 
2 27  C   n 
2 28  C   n 
2 29  U   n 
2 30  U   n 
2 31  A   n 
2 32  G   n 
2 33  U   n 
2 34  G   n 
2 35  C   n 
2 36  G   n 
3 1   DT  n 
3 2   DC  n 
3 3   DA  n 
3 4   DG  n 
3 5   DC  n 
3 6   DG  n 
3 7   DT  n 
3 8   DT  n 
3 9   DA  n 
3 10  DA  n 
3 11  DA  n 
3 12  DA  n 
3 13  DA  n 
3 14  DA  n 
3 15  DT  n 
3 16  DT  n 
3 17  DG  n 
3 18  DA  n 
3 19  DT  n 
3 20  DG  n 
3 21  DA  n 
3 22  DT  n 
3 23  DT  n 
3 24  DG  n 
3 25  DC  n 
3 26  DC  n 
3 27  DT  n 
3 28  DT  n 
3 29  DA  n 
3 30  DG  n 
3 31  DG  n 
3 32  DG  n 
3 33  DG  n 
3 34  DC  n 
4 1   DT  n 
4 2   DT  n 
4 3   DG  n 
4 4   DC  n 
4 5   DA  n 
4 6   DT  n 
4 7   DC  n 
4 8   DG  n 
4 9   DA  n 
4 10  DA  n 
4 11  DA  n 
4 12  DC  n 
4 13  DC  n 
4 14  DA  n 
4 15  DC  n 
4 16  DA  n 
4 17  DG  n 
4 18  DC  n 
4 19  DC  n 
4 20  DA  n 
4 21  DA  n 
4 22  DG  n 
4 23  DG  n 
4 24  DG  n 
4 25  DA  n 
4 26  DA  n 
5 1   DT  n 
5 2   DT  n 
5 3   DC  n 
5 4   DC  n 
5 5   DC  n 
5 6   DT  n 
5 7   DT  n 
5 8   DG  n 
5 9   DG  n 
5 10  DC  n 
5 11  DT  n 
5 12  DG  n 
5 13  DT  n 
5 14  DG  n 
5 15  DG  n 
5 16  DT  n 
5 17  DT  n 
5 18  DT  n 
5 19  DC  n 
5 20  DG  n 
5 21  DA  n 
5 22  DT  n 
5 23  DG  n 
5 24  DC  n 
5 25  DA  n 
5 26  DA  n 
5 27  DG  n 
5 28  DC  n 
5 29  DC  n 
5 30  DC  n 
5 31  DC  n 
5 32  DT  n 
5 33  DA  n 
5 34  DA  n 
6 1   DG  n 
6 2   DG  n 
6 3   DC  n 
6 4   DA  n 
6 5   DA  n 
6 6   DT  n 
6 7   DC  n 
6 8   DA  n 
6 9   DT  n 
6 10  DC  n 
6 11  DA  n 
6 12  DA  n 
6 13  DT  n 
6 14  DT  n 
6 15  DT  n 
6 16  DT  n 
6 17  DT  n 
6 18  DT  n 
6 19  DA  n 
6 20  DA  n 
6 21  DC  n 
6 22  DG  n 
6 23  DC  n 
6 24  DT  n 
6 25  DG  n 
6 26  DA  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 331 ? ? DWQ19_11745 ? ? ? ? ? ? 'Thermoproteota archaeon' 2056631 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 36  ? ? ?           ? ? ? ? ? ? 'Thermoproteota archaeon' 2056631 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
3 1 sample 1 34 'Escherichia coli' ? 562 ? 
4 1 sample 1 26 'Escherichia coli' ? 562 ? 
5 1 sample 1 34 'Escherichia coli' ? 562 ? 
6 1 sample 1 26 'Escherichia coli' ? 562 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"          ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
MG  non-polymer         . 'MAGNESIUM ION'                      ? 'Mg 2'            24.305  
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"           ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   ?   ?   ?   A . n 
A 1 3   ASN 3   3   ?   ?   ?   A . n 
A 1 4   ASP 4   4   ?   ?   ?   A . n 
A 1 5   ILE 5   5   ?   ?   ?   A . n 
A 1 6   THR 6   6   6   THR THR A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ALA 9   9   9   ALA ALA A . n 
A 1 10  VAL 10  10  10  VAL VAL A . n 
A 1 11  ASP 11  11  11  ASP ASP A . n 
A 1 12  TRP 12  12  12  TRP TRP A . n 
A 1 13  SER 13  13  13  SER SER A . n 
A 1 14  HIS 14  14  14  HIS HIS A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  GLU 16  16  16  GLU GLU A . n 
A 1 17  ARG 17  17  17  ARG ARG A . n 
A 1 18  LYS 18  18  18  LYS LYS A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  LYS 25  25  25  LYS LYS A . n 
A 1 26  LYS 26  26  26  LYS LYS A . n 
A 1 27  ILE 27  27  27  ILE ILE A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  LYS 30  30  30  LYS LYS A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  PRO 34  34  34  PRO PRO A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  SER 36  36  36  SER SER A . n 
A 1 37  ASP 37  37  37  ASP ASP A . n 
A 1 38  VAL 38  38  38  VAL VAL A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  ILE 40  40  40  ILE ILE A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  ALA 42  42  42  ALA ALA A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  ASN 44  44  44  ASN ASN A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  GLN 47  47  47  GLN GLN A . n 
A 1 48  LYS 48  48  48  LYS LYS A . n 
A 1 49  TYR 49  49  49  TYR TYR A . n 
A 1 50  ALA 50  50  50  ALA ALA A . n 
A 1 51  ALA 51  51  51  ALA ALA A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  PHE 53  53  53  PHE PHE A . n 
A 1 54  ILE 54  54  54  ILE ILE A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  VAL 56  56  56  VAL VAL A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  ALA 58  58  58  ALA ALA A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  ARG 62  62  62  ARG ARG A . n 
A 1 63  CYS 63  63  63  CYS CYS A . n 
A 1 64  SER 64  64  64  SER SER A . n 
A 1 65  THR 65  65  65  THR THR A . n 
A 1 66  ASN 66  66  66  ASN ASN A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  ALA 71  71  71  ALA ALA A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  LYS 73  73  73  LYS LYS A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  TYR 75  75  ?   ?   ?   A . n 
A 1 76  GLN 76  76  ?   ?   ?   A . n 
A 1 77  LYS 77  77  ?   ?   ?   A . n 
A 1 78  LYS 78  78  ?   ?   ?   A . n 
A 1 79  VAL 79  79  ?   ?   ?   A . n 
A 1 80  ASP 80  80  ?   ?   ?   A . n 
A 1 81  ALA 81  81  ?   ?   ?   A . n 
A 1 82  ALA 82  82  ?   ?   ?   A . n 
A 1 83  PHE 83  83  ?   ?   ?   A . n 
A 1 84  ALA 84  84  ?   ?   ?   A . n 
A 1 85  LYS 85  85  ?   ?   ?   A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  ASP 87  87  87  ASP ASP A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  ASN 89  89  89  ASN ASN A . n 
A 1 90  ASP 90  90  90  ASP ASP A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  LYS 92  92  92  LYS LYS A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  ILE 94  94  94  ILE ILE A . n 
A 1 95  TRP 95  95  95  TRP TRP A . n 
A 1 96  ALA 96  96  96  ALA ALA A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  GLN 99  99  99  GLN GLN A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 HIS 101 101 101 HIS HIS A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 ARG 106 106 106 ARG ARG A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 MET 108 108 108 MET MET A . n 
A 1 109 LYS 109 109 109 LYS LYS A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 GLU 111 111 111 GLU GLU A . n 
A 1 112 PRO 112 112 112 PRO PRO A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 LEU 114 114 114 LEU LEU A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 TYR 117 117 117 TYR TYR A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 ASP 123 123 123 ASP ASP A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 GLN 125 125 125 GLN GLN A . n 
A 1 126 GLU 126 126 126 GLU GLU A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 ARG 128 128 128 ARG ARG A . n 
A 1 129 ILE 129 129 129 ILE ILE A . n 
A 1 130 ARG 130 130 130 ARG ARG A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 GLY 132 132 132 GLY GLY A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 LEU 135 135 135 LEU LEU A . n 
A 1 136 TYR 136 136 136 TYR TYR A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 ASP 138 138 138 ASP ASP A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 MET 143 143 143 MET MET A . n 
A 1 144 GLU 144 144 144 GLU GLU A . n 
A 1 145 GLU 145 145 145 GLU GLU A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 LYS 151 151 151 LYS LYS A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 GLY 153 153 153 GLY GLY A . n 
A 1 154 GLU 154 154 154 GLU GLU A . n 
A 1 155 HIS 155 155 155 HIS HIS A . n 
A 1 156 GLU 156 156 156 GLU GLU A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 LYS 158 158 158 LYS LYS A . n 
A 1 159 LYS 159 159 159 LYS LYS A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 VAL 161 161 161 VAL VAL A . n 
A 1 162 ASP 162 162 162 ASP ASP A . n 
A 1 163 LYS 163 163 163 LYS LYS A . n 
A 1 164 GLU 164 164 164 GLU GLU A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 ASN 167 167 167 ASN ASN A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 TYR 171 171 171 TYR TYR A . n 
A 1 172 THR 172 172 172 THR THR A . n 
A 1 173 GLN 173 173 173 GLN GLN A . n 
A 1 174 TRP 174 174 174 TRP TRP A . n 
A 1 175 LEU 175 175 175 LEU LEU A . n 
A 1 176 GLN 176 176 176 GLN GLN A . n 
A 1 177 HIS 177 177 177 HIS HIS A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 LYS 179 179 179 LYS LYS A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 GLY 188 188 188 GLY GLY A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 ASP 195 195 195 ASP ASP A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 ASP 197 197 197 ASP ASP A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 LYS 204 204 204 LYS LYS A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 TRP 206 206 206 TRP TRP A . n 
A 1 207 ALA 207 207 207 ALA ALA A . n 
A 1 208 TYR 208 208 208 TYR TYR A . n 
A 1 209 ALA 209 209 209 ALA ALA A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 TYR 211 211 211 TYR TYR A . n 
A 1 212 SER 212 212 212 SER SER A . n 
A 1 213 VAL 213 213 213 VAL VAL A . n 
A 1 214 ASP 214 214 214 ASP ASP A . n 
A 1 215 ASN 215 215 215 ASN ASN A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 LYS 217 217 217 LYS LYS A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 GLN 219 219 219 GLN GLN A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 ARG 221 221 221 ARG ARG A . n 
A 1 222 LYS 222 222 222 LYS LYS A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 SER 227 227 227 SER SER A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 TRP 229 229 229 TRP TRP A . n 
A 1 230 LYS 230 230 230 LYS LYS A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 LYS 232 232 232 LYS LYS A . n 
A 1 233 ILE 233 233 233 ILE ILE A . n 
A 1 234 ARG 234 234 234 ARG ARG A . n 
A 1 235 THR 235 235 235 THR THR A . n 
A 1 236 HIS 236 236 236 HIS HIS A . n 
A 1 237 CYS 237 237 237 CYS CYS A . n 
A 1 238 TYR 238 238 238 TYR TYR A . n 
A 1 239 ASN 239 239 239 ASN ASN A . n 
A 1 240 ILE 240 240 240 ILE ILE A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 SER 243 243 243 SER SER A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 LYS 246 246 246 LYS LYS A . n 
A 1 247 GLN 247 247 247 GLN GLN A . n 
A 1 248 ARG 248 248 248 ARG ARG A . n 
A 1 249 THR 249 249 249 THR THR A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 TYR 252 252 252 TYR TYR A . n 
A 1 253 ARG 253 253 253 ARG ARG A . n 
A 1 254 GLU 254 254 254 GLU GLU A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 TYR 256 256 256 TYR TYR A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 GLU 259 259 259 GLU GLU A . n 
A 1 260 LYS 260 260 260 LYS LYS A . n 
A 1 261 ALA 261 261 261 ALA ALA A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 GLN 263 263 263 GLN GLN A . n 
A 1 264 ARG 264 264 264 ARG ARG A . n 
A 1 265 PRO 265 265 265 PRO PRO A . n 
A 1 266 LYS 266 266 266 LYS LYS A . n 
A 1 267 VAL 267 267 267 VAL VAL A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 SER 269 269 269 SER SER A . n 
A 1 270 ASP 270 270 270 ASP ASP A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 HIS 272 272 272 HIS HIS A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 HIS 274 274 274 HIS HIS A . n 
A 1 275 ASN 275 275 275 ASN ASN A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 VAL 278 278 278 VAL VAL A . n 
A 1 279 ARG 279 279 279 ARG ARG A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 VAL 281 281 281 VAL VAL A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 VAL 284 284 284 VAL VAL A . n 
A 1 285 PHE 285 285 285 PHE PHE A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 GLN 287 287 287 GLN GLN A . n 
A 1 288 HIS 288 288 288 HIS HIS A . n 
A 1 289 TYR 289 289 289 TYR TYR A . n 
A 1 290 TRP 290 290 290 TRP TRP A . n 
A 1 291 VAL 291 291 291 VAL VAL A . n 
A 1 292 VAL 292 292 292 VAL VAL A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 GLU 295 295 295 GLU GLU A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 PHE 299 299 299 PHE PHE A . n 
A 1 300 SER 300 300 300 SER SER A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 SER 302 302 302 SER SER A . n 
A 1 303 LYS 303 303 ?   ?   ?   A . n 
A 1 304 PRO 304 304 ?   ?   ?   A . n 
A 1 305 TRP 305 305 ?   ?   ?   A . n 
A 1 306 ILE 306 306 ?   ?   ?   A . n 
A 1 307 LEU 307 307 ?   ?   ?   A . n 
A 1 308 GLU 308 308 ?   ?   ?   A . n 
A 1 309 HIS 309 309 ?   ?   ?   A . n 
A 1 310 GLY 310 310 ?   ?   ?   A . n 
A 1 311 GLY 311 311 ?   ?   ?   A . n 
A 1 312 HIS 312 312 ?   ?   ?   A . n 
A 1 313 VAL 313 313 ?   ?   ?   A . n 
A 1 314 ASP 314 314 ?   ?   ?   A . n 
A 1 315 TYR 315 315 ?   ?   ?   A . n 
A 1 316 ILE 316 316 ?   ?   ?   A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 PRO 318 318 318 PRO PRO A . n 
A 1 319 PRO 319 319 319 PRO PRO A . n 
A 1 320 HIS 320 320 320 HIS HIS A . n 
A 1 321 TRP 321 321 321 TRP TRP A . n 
A 1 322 ASN 322 322 322 ASN ASN A . n 
A 1 323 LYS 323 323 ?   ?   ?   A . n 
A 1 324 VAL 324 324 ?   ?   ?   A . n 
A 1 325 GLU 325 325 ?   ?   ?   A . n 
A 1 326 ILE 326 326 ?   ?   ?   A . n 
A 1 327 LYS 327 327 ?   ?   ?   A . n 
A 1 328 PRO 328 328 ?   ?   ?   A . n 
A 1 329 CYS 329 329 ?   ?   ?   A . n 
A 1 330 LYS 330 330 ?   ?   ?   A . n 
A 1 331 PRO 331 331 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ASP 2   2   ?   ?   ?   B . n 
B 1 3   ASN 3   3   ?   ?   ?   B . n 
B 1 4   ASP 4   4   ?   ?   ?   B . n 
B 1 5   ILE 5   5   ?   ?   ?   B . n 
B 1 6   THR 6   6   6   THR THR B . n 
B 1 7   ILE 7   7   7   ILE ILE B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   ALA 9   9   9   ALA ALA B . n 
B 1 10  VAL 10  10  10  VAL VAL B . n 
B 1 11  ASP 11  11  11  ASP ASP B . n 
B 1 12  TRP 12  12  12  TRP TRP B . n 
B 1 13  SER 13  13  13  SER SER B . n 
B 1 14  HIS 14  14  14  HIS HIS B . n 
B 1 15  GLU 15  15  15  GLU GLU B . n 
B 1 16  GLU 16  16  16  GLU GLU B . n 
B 1 17  ARG 17  17  17  ARG ARG B . n 
B 1 18  LYS 18  18  18  LYS LYS B . n 
B 1 19  LEU 19  19  19  LEU LEU B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  PHE 22  22  22  PHE PHE B . n 
B 1 23  ASP 23  23  23  ASP ASP B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  LYS 25  25  25  LYS LYS B . n 
B 1 26  LYS 26  26  26  LYS LYS B . n 
B 1 27  ILE 27  27  27  ILE ILE B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  LYS 30  30  30  LYS LYS B . n 
B 1 31  LEU 31  31  31  LEU LEU B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  PRO 34  34  34  PRO PRO B . n 
B 1 35  SER 35  35  35  SER SER B . n 
B 1 36  SER 36  36  36  SER SER B . n 
B 1 37  ASP 37  37  37  ASP ASP B . n 
B 1 38  VAL 38  38  38  VAL VAL B . n 
B 1 39  ILE 39  39  39  ILE ILE B . n 
B 1 40  ILE 40  40  40  ILE ILE B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  ALA 42  42  42  ALA ALA B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  ASN 44  44  44  ASN ASN B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  PRO 46  46  46  PRO PRO B . n 
B 1 47  GLN 47  47  47  GLN GLN B . n 
B 1 48  LYS 48  48  48  LYS LYS B . n 
B 1 49  TYR 49  49  49  TYR TYR B . n 
B 1 50  ALA 50  50  50  ALA ALA B . n 
B 1 51  ALA 51  51  51  ALA ALA B . n 
B 1 52  PRO 52  52  52  PRO PRO B . n 
B 1 53  PHE 53  53  53  PHE PHE B . n 
B 1 54  ILE 54  54  54  ILE ILE B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  VAL 56  56  56  VAL VAL B . n 
B 1 57  GLY 57  57  57  GLY GLY B . n 
B 1 58  ALA 58  58  58  ALA ALA B . n 
B 1 59  LYS 59  59  59  LYS LYS B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  ARG 62  62  62  ARG ARG B . n 
B 1 63  CYS 63  63  63  CYS CYS B . n 
B 1 64  SER 64  64  64  SER SER B . n 
B 1 65  THR 65  65  65  THR THR B . n 
B 1 66  ASN 66  66  66  ASN ASN B . n 
B 1 67  ALA 67  67  67  ALA ALA B . n 
B 1 68  THR 68  68  68  THR THR B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  ALA 71  71  71  ALA ALA B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  LYS 73  73  73  LYS LYS B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  TYR 75  75  ?   ?   ?   B . n 
B 1 76  GLN 76  76  ?   ?   ?   B . n 
B 1 77  LYS 77  77  ?   ?   ?   B . n 
B 1 78  LYS 78  78  ?   ?   ?   B . n 
B 1 79  VAL 79  79  ?   ?   ?   B . n 
B 1 80  ASP 80  80  ?   ?   ?   B . n 
B 1 81  ALA 81  81  ?   ?   ?   B . n 
B 1 82  ALA 82  82  ?   ?   ?   B . n 
B 1 83  PHE 83  83  ?   ?   ?   B . n 
B 1 84  ALA 84  84  ?   ?   ?   B . n 
B 1 85  LYS 85  85  ?   ?   ?   B . n 
B 1 86  ASN 86  86  86  ASN ASN B . n 
B 1 87  ASP 87  87  87  ASP ASP B . n 
B 1 88  GLU 88  88  88  GLU GLU B . n 
B 1 89  ASN 89  89  89  ASN ASN B . n 
B 1 90  ASP 90  90  90  ASP ASP B . n 
B 1 91  SER 91  91  91  SER SER B . n 
B 1 92  LYS 92  92  92  LYS LYS B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  ILE 94  94  94  ILE ILE B . n 
B 1 95  TRP 95  95  95  TRP TRP B . n 
B 1 96  ALA 96  96  96  ALA ALA B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  TYR 98  98  98  TYR TYR B . n 
B 1 99  GLN 99  99  99  GLN GLN B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 HIS 101 101 101 HIS HIS B . n 
B 1 102 PRO 102 102 102 PRO PRO B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 ARG 106 106 106 ARG ARG B . n 
B 1 107 GLU 107 107 107 GLU GLU B . n 
B 1 108 MET 108 108 108 MET MET B . n 
B 1 109 LYS 109 109 109 LYS LYS B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 GLU 111 111 111 GLU GLU B . n 
B 1 112 PRO 112 112 112 PRO PRO B . n 
B 1 113 PRO 113 113 113 PRO PRO B . n 
B 1 114 LEU 114 114 114 LEU LEU B . n 
B 1 115 SER 115 115 115 SER SER B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 TYR 117 117 117 TYR TYR B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 ILE 120 120 120 ILE ILE B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 LYS 122 122 122 LYS LYS B . n 
B 1 123 ASP 123 123 123 ASP ASP B . n 
B 1 124 TYR 124 124 124 TYR TYR B . n 
B 1 125 GLN 125 125 125 GLN GLN B . n 
B 1 126 GLU 126 126 126 GLU GLU B . n 
B 1 127 VAL 127 127 127 VAL VAL B . n 
B 1 128 ARG 128 128 128 ARG ARG B . n 
B 1 129 ILE 129 129 129 ILE ILE B . n 
B 1 130 ARG 130 130 130 ARG ARG B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 GLY 132 132 132 GLY GLY B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 ARG 134 134 134 ARG ARG B . n 
B 1 135 LEU 135 135 135 LEU LEU B . n 
B 1 136 TYR 136 136 136 TYR TYR B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 ASP 138 138 138 ASP ASP B . n 
B 1 139 ARG 139 139 139 ARG ARG B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 ASP 141 141 141 ASP ASP B . n 
B 1 142 ALA 142 142 142 ALA ALA B . n 
B 1 143 MET 143 143 143 MET MET B . n 
B 1 144 GLU 144 144 144 GLU GLU B . n 
B 1 145 GLU 145 145 145 GLU GLU B . n 
B 1 146 PHE 146 146 146 PHE PHE B . n 
B 1 147 PHE 147 147 147 PHE PHE B . n 
B 1 148 LYS 148 148 148 LYS LYS B . n 
B 1 149 ILE 149 149 149 ILE ILE B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 LYS 151 151 151 LYS LYS B . n 
B 1 152 LYS 152 152 152 LYS LYS B . n 
B 1 153 GLY 153 153 153 GLY GLY B . n 
B 1 154 GLU 154 154 154 GLU GLU B . n 
B 1 155 HIS 155 155 155 HIS HIS B . n 
B 1 156 GLU 156 156 156 GLU GLU B . n 
B 1 157 LEU 157 157 157 LEU LEU B . n 
B 1 158 LYS 158 158 158 LYS LYS B . n 
B 1 159 LYS 159 159 159 LYS LYS B . n 
B 1 160 ALA 160 160 160 ALA ALA B . n 
B 1 161 VAL 161 161 161 VAL VAL B . n 
B 1 162 ASP 162 162 162 ASP ASP B . n 
B 1 163 LYS 163 163 163 LYS LYS B . n 
B 1 164 GLU 164 164 164 GLU GLU B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 ASN 167 167 167 ASN ASN B . n 
B 1 168 HIS 168 168 168 HIS HIS B . n 
B 1 169 PRO 169 169 169 PRO PRO B . n 
B 1 170 VAL 170 170 170 VAL VAL B . n 
B 1 171 TYR 171 171 171 TYR TYR B . n 
B 1 172 THR 172 172 172 THR THR B . n 
B 1 173 GLN 173 173 173 GLN GLN B . n 
B 1 174 TRP 174 174 174 TRP TRP B . n 
B 1 175 LEU 175 175 175 LEU LEU B . n 
B 1 176 GLN 176 176 176 GLN GLN B . n 
B 1 177 HIS 177 177 177 HIS HIS B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 LYS 179 179 179 LYS LYS B . n 
B 1 180 GLY 180 180 180 GLY GLY B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 GLY 182 182 182 GLY GLY B . n 
B 1 183 PRO 183 183 183 PRO PRO B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 VAL 185 185 185 VAL VAL B . n 
B 1 186 ALA 186 186 186 ALA ALA B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 GLY 188 188 188 GLY GLY B . n 
B 1 189 LEU 189 189 189 LEU LEU B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 ILE 193 193 193 ILE ILE B . n 
B 1 194 GLY 194 194 194 GLY GLY B . n 
B 1 195 ASP 195 195 195 ASP ASP B . n 
B 1 196 ILE 196 196 196 ILE ILE B . n 
B 1 197 ASP 197 197 197 ASP ASP B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 ASP 200 200 200 ASP ASP B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 LYS 204 204 204 LYS LYS B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 TRP 206 206 206 TRP TRP B . n 
B 1 207 ALA 207 207 207 ALA ALA B . n 
B 1 208 TYR 208 208 208 TYR TYR B . n 
B 1 209 ALA 209 209 209 ALA ALA B . n 
B 1 210 GLY 210 210 210 GLY GLY B . n 
B 1 211 TYR 211 211 211 TYR TYR B . n 
B 1 212 SER 212 212 212 SER SER B . n 
B 1 213 VAL 213 213 213 VAL VAL B . n 
B 1 214 ASP 214 214 214 ASP ASP B . n 
B 1 215 ASN 215 215 215 ASN ASN B . n 
B 1 216 GLY 216 216 216 GLY GLY B . n 
B 1 217 LYS 217 217 217 LYS LYS B . n 
B 1 218 VAL 218 218 218 VAL VAL B . n 
B 1 219 GLN 219 219 219 GLN GLN B . n 
B 1 220 LYS 220 220 220 LYS LYS B . n 
B 1 221 ARG 221 221 221 ARG ARG B . n 
B 1 222 LYS 222 222 222 LYS LYS B . n 
B 1 223 LYS 223 223 223 LYS LYS B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 VAL 225 225 225 VAL VAL B . n 
B 1 226 ALA 226 226 226 ALA ALA B . n 
B 1 227 SER 227 227 227 SER SER B . n 
B 1 228 ASN 228 228 228 ASN ASN B . n 
B 1 229 TRP 229 229 229 TRP TRP B . n 
B 1 230 LYS 230 230 230 LYS LYS B . n 
B 1 231 ASN 231 231 231 ASN ASN B . n 
B 1 232 LYS 232 232 232 LYS LYS B . n 
B 1 233 ILE 233 233 233 ILE ILE B . n 
B 1 234 ARG 234 234 234 ARG ARG B . n 
B 1 235 THR 235 235 235 THR THR B . n 
B 1 236 HIS 236 236 236 HIS HIS B . n 
B 1 237 CYS 237 237 237 CYS CYS B . n 
B 1 238 TYR 238 238 238 TYR TYR B . n 
B 1 239 ASN 239 239 239 ASN ASN B . n 
B 1 240 ILE 240 240 240 ILE ILE B . n 
B 1 241 VAL 241 241 241 VAL VAL B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 SER 243 243 243 SER SER B . n 
B 1 244 PHE 244 244 244 PHE PHE B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 LYS 246 246 246 LYS LYS B . n 
B 1 247 GLN 247 247 247 GLN GLN B . n 
B 1 248 ARG 248 248 248 ARG ARG B . n 
B 1 249 THR 249 249 249 THR THR B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 TYR 252 252 252 TYR TYR B . n 
B 1 253 ARG 253 253 253 ARG ARG B . n 
B 1 254 GLU 254 254 254 GLU GLU B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 TYR 256 256 256 TYR TYR B . n 
B 1 257 ASP 257 257 257 ASP ASP B . n 
B 1 258 ALA 258 258 258 ALA ALA B . n 
B 1 259 GLU 259 259 259 GLU GLU B . n 
B 1 260 LYS 260 260 260 LYS LYS B . n 
B 1 261 ALA 261 261 261 ALA ALA B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 GLN 263 263 263 GLN GLN B . n 
B 1 264 ARG 264 264 264 ARG ARG B . n 
B 1 265 PRO 265 265 265 PRO PRO B . n 
B 1 266 LYS 266 266 266 LYS LYS B . n 
B 1 267 VAL 267 267 267 VAL VAL B . n 
B 1 268 GLU 268 268 268 GLU GLU B . n 
B 1 269 SER 269 269 269 SER SER B . n 
B 1 270 ASP 270 270 270 ASP ASP B . n 
B 1 271 GLY 271 271 271 GLY GLY B . n 
B 1 272 HIS 272 272 272 HIS HIS B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 HIS 274 274 274 HIS HIS B . n 
B 1 275 ASN 275 275 275 ASN ASN B . n 
B 1 276 ARG 276 276 276 ARG ARG B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 VAL 278 278 278 VAL VAL B . n 
B 1 279 ARG 279 279 279 ARG ARG B . n 
B 1 280 LYS 280 280 280 LYS LYS B . n 
B 1 281 VAL 281 281 281 VAL VAL B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 LYS 283 283 283 LYS LYS B . n 
B 1 284 VAL 284 284 284 VAL VAL B . n 
B 1 285 PHE 285 285 285 PHE PHE B . n 
B 1 286 LEU 286 286 286 LEU LEU B . n 
B 1 287 GLN 287 287 287 GLN GLN B . n 
B 1 288 HIS 288 288 288 HIS HIS B . n 
B 1 289 TYR 289 289 289 TYR TYR B . n 
B 1 290 TRP 290 290 290 TRP TRP B . n 
B 1 291 VAL 291 291 291 VAL VAL B . n 
B 1 292 VAL 292 292 292 VAL VAL B . n 
B 1 293 SER 293 293 293 SER SER B . n 
B 1 294 ARG 294 294 294 ARG ARG B . n 
B 1 295 GLU 295 295 295 GLU GLU B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 ALA 297 297 297 ALA ALA B . n 
B 1 298 GLY 298 298 298 GLY GLY B . n 
B 1 299 PHE 299 299 299 PHE PHE B . n 
B 1 300 SER 300 300 300 SER SER B . n 
B 1 301 VAL 301 301 301 VAL VAL B . n 
B 1 302 SER 302 302 302 SER SER B . n 
B 1 303 LYS 303 303 303 LYS LYS B . n 
B 1 304 PRO 304 304 ?   ?   ?   B . n 
B 1 305 TRP 305 305 ?   ?   ?   B . n 
B 1 306 ILE 306 306 ?   ?   ?   B . n 
B 1 307 LEU 307 307 ?   ?   ?   B . n 
B 1 308 GLU 308 308 ?   ?   ?   B . n 
B 1 309 HIS 309 309 ?   ?   ?   B . n 
B 1 310 GLY 310 310 ?   ?   ?   B . n 
B 1 311 GLY 311 311 ?   ?   ?   B . n 
B 1 312 HIS 312 312 ?   ?   ?   B . n 
B 1 313 VAL 313 313 ?   ?   ?   B . n 
B 1 314 ASP 314 314 ?   ?   ?   B . n 
B 1 315 TYR 315 315 ?   ?   ?   B . n 
B 1 316 ILE 316 316 316 ILE ILE B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 PRO 318 318 318 PRO PRO B . n 
B 1 319 PRO 319 319 319 PRO PRO B . n 
B 1 320 HIS 320 320 320 HIS HIS B . n 
B 1 321 TRP 321 321 321 TRP TRP B . n 
B 1 322 ASN 322 322 322 ASN ASN B . n 
B 1 323 LYS 323 323 ?   ?   ?   B . n 
B 1 324 VAL 324 324 ?   ?   ?   B . n 
B 1 325 GLU 325 325 ?   ?   ?   B . n 
B 1 326 ILE 326 326 ?   ?   ?   B . n 
B 1 327 LYS 327 327 ?   ?   ?   B . n 
B 1 328 PRO 328 328 ?   ?   ?   B . n 
B 1 329 CYS 329 329 ?   ?   ?   B . n 
B 1 330 LYS 330 330 ?   ?   ?   B . n 
B 1 331 PRO 331 331 ?   ?   ?   B . n 
C 2 1   A   1   1   1   A   A   C . n 
C 2 2   G   2   2   2   G   G   C . n 
C 2 3   C   3   3   3   C   C   C . n 
C 2 4   C   4   4   4   C   C   C . n 
C 2 5   A   5   5   5   A   A   C . n 
C 2 6   U   6   6   6   U   U   C . n 
C 2 7   G   7   7   7   G   G   C . n 
C 2 8   C   8   8   8   C   C   C . n 
C 2 9   A   9   9   9   A   A   C . n 
C 2 10  A   10  10  10  A   A   C . n 
C 2 11  G   11  11  11  G   G   C . n 
C 2 12  C   12  12  12  C   C   C . n 
C 2 13  C   13  13  13  C   C   C . n 
C 2 14  C   14  14  14  C   C   C . n 
C 2 15  U   15  15  15  U   U   C . n 
C 2 16  G   16  16  16  G   G   C . n 
C 2 17  A   17  17  17  A   A   C . n 
C 2 18  A   18  18  18  A   A   C . n 
C 2 19  A   19  19  19  A   A   C . n 
C 2 20  C   20  20  20  C   C   C . n 
C 2 21  C   21  21  21  C   C   C . n 
C 2 22  C   22  22  22  C   C   C . n 
C 2 23  A   23  23  23  A   A   C . n 
C 2 24  U   24  24  24  U   U   C . n 
C 2 25  U   25  25  25  U   U   C . n 
C 2 26  G   26  26  26  G   G   C . n 
C 2 27  C   27  27  27  C   C   C . n 
C 2 28  C   28  28  28  C   C   C . n 
C 2 29  U   29  29  29  U   U   C . n 
C 2 30  U   30  30  30  U   U   C . n 
C 2 31  A   31  31  31  A   A   C . n 
C 2 32  G   32  32  32  G   G   C . n 
C 2 33  U   33  33  33  U   U   C . n 
C 2 34  G   34  34  34  G   G   C . n 
C 2 35  C   35  35  35  C   C   C . n 
C 2 36  G   36  36  36  G   G   C . n 
D 3 1   DT  1   -34 ?   ?   ?   D . n 
D 3 2   DC  2   -33 ?   ?   ?   D . n 
D 3 3   DA  3   -32 ?   ?   ?   D . n 
D 3 4   DG  4   -31 ?   ?   ?   D . n 
D 3 5   DC  5   -30 ?   ?   ?   D . n 
D 3 6   DG  6   -29 ?   ?   ?   D . n 
D 3 7   DT  7   -28 ?   ?   ?   D . n 
D 3 8   DT  8   -27 ?   ?   ?   D . n 
D 3 9   DA  9   -26 ?   ?   ?   D . n 
D 3 10  DA  10  -25 ?   ?   ?   D . n 
D 3 11  DA  11  -24 ?   ?   ?   D . n 
D 3 12  DA  12  -23 -23 DA  DA  D . n 
D 3 13  DA  13  -22 -22 DA  DA  D . n 
D 3 14  DA  14  -21 -21 DA  DA  D . n 
D 3 15  DT  15  -20 -20 DT  DT  D . n 
D 3 16  DT  16  -19 -19 DT  DT  D . n 
D 3 17  DG  17  -18 -18 DG  DG  D . n 
D 3 18  DA  18  -17 -17 DA  DA  D . n 
D 3 19  DT  19  -16 -16 DT  DT  D . n 
D 3 20  DG  20  -15 -15 DG  DG  D . n 
D 3 21  DA  21  -14 -14 DA  DA  D . n 
D 3 22  DT  22  -13 -13 DT  DT  D . n 
D 3 23  DT  23  -12 -12 DT  DT  D . n 
D 3 24  DG  24  -11 -11 DG  DG  D . n 
D 3 25  DC  25  -10 -10 DC  DC  D . n 
D 3 26  DC  26  -9  -9  DC  DC  D . n 
D 3 27  DT  27  -8  -8  DT  DT  D . n 
D 3 28  DT  28  -7  -7  DT  DT  D . n 
D 3 29  DA  29  -6  -6  DA  DA  D . n 
D 3 30  DG  30  -5  -5  DG  DG  D . n 
D 3 31  DG  31  -4  -4  DG  DG  D . n 
D 3 32  DG  32  -3  -3  DG  DG  D . n 
D 3 33  DG  33  -2  -2  DG  DG  D . n 
D 3 34  DC  34  -1  -1  DC  DC  D . n 
E 4 1   DT  1   1   1   DT  DT  F . n 
E 4 2   DT  2   2   2   DT  DT  F . n 
E 4 3   DG  3   3   3   DG  DG  F . n 
E 4 4   DC  4   4   4   DC  DC  F . n 
E 4 5   DA  5   5   5   DA  DA  F . n 
E 4 6   DT  6   6   6   DT  DT  F . n 
E 4 7   DC  7   7   7   DC  DC  F . n 
E 4 8   DG  8   8   8   DG  DG  F . n 
E 4 9   DA  9   9   9   DA  DA  F . n 
E 4 10  DA  10  10  10  DA  DA  F . n 
E 4 11  DA  11  11  11  DA  DA  F . n 
E 4 12  DC  12  12  12  DC  DC  F . n 
E 4 13  DC  13  13  13  DC  DC  F . n 
E 4 14  DA  14  14  14  DA  DA  F . n 
E 4 15  DC  15  15  15  DC  DC  F . n 
E 4 16  DA  16  16  ?   ?   ?   F . n 
E 4 17  DG  17  17  ?   ?   ?   F . n 
E 4 18  DC  18  18  ?   ?   ?   F . n 
E 4 19  DC  19  19  ?   ?   ?   F . n 
E 4 20  DA  20  20  ?   ?   ?   F . n 
E 4 21  DA  21  21  ?   ?   ?   F . n 
E 4 22  DG  22  22  ?   ?   ?   F . n 
E 4 23  DG  23  23  ?   ?   ?   F . n 
E 4 24  DG  24  24  ?   ?   ?   F . n 
E 4 25  DA  25  25  ?   ?   ?   F . n 
E 4 26  DA  26  26  ?   ?   ?   F . n 
F 5 1   DT  1   -34 ?   ?   ?   E . n 
F 5 2   DT  2   -33 ?   ?   ?   E . n 
F 5 3   DC  3   -32 ?   ?   ?   E . n 
F 5 4   DC  4   -31 ?   ?   ?   E . n 
F 5 5   DC  5   -30 ?   ?   ?   E . n 
F 5 6   DT  6   -29 ?   ?   ?   E . n 
F 5 7   DT  7   -28 ?   ?   ?   E . n 
F 5 8   DG  8   -27 ?   ?   ?   E . n 
F 5 9   DG  9   -26 ?   ?   ?   E . n 
F 5 10  DC  10  -25 ?   ?   ?   E . n 
F 5 11  DT  11  -24 ?   ?   ?   E . n 
F 5 12  DG  12  -23 -23 DG  DG  E . n 
F 5 13  DT  13  -22 -22 DT  DT  E . n 
F 5 14  DG  14  -21 -21 DG  DG  E . n 
F 5 15  DG  15  -20 -20 DG  DG  E . n 
F 5 16  DT  16  -19 -19 DT  DT  E . n 
F 5 17  DT  17  -18 -18 DT  DT  E . n 
F 5 18  DT  18  -17 -17 DT  DT  E . n 
F 5 19  DC  19  -16 -16 DC  DC  E . n 
F 5 20  DG  20  -15 -15 DG  DG  E . n 
F 5 21  DA  21  -14 -14 DA  DA  E . n 
F 5 22  DT  22  -13 -13 DT  DT  E . n 
F 5 23  DG  23  -12 -12 DG  DG  E . n 
F 5 24  DC  24  -11 -11 DC  DC  E . n 
F 5 25  DA  25  -10 -10 DA  DA  E . n 
F 5 26  DA  26  -9  -9  DA  DA  E . n 
F 5 27  DG  27  -8  -8  DG  DG  E . n 
F 5 28  DC  28  -7  -7  DC  DC  E . n 
F 5 29  DC  29  -6  -6  DC  DC  E . n 
F 5 30  DC  30  -5  -5  DC  DC  E . n 
F 5 31  DC  31  -4  -4  DC  DC  E . n 
F 5 32  DT  32  -3  -3  DT  DT  E . n 
F 5 33  DA  33  -2  -2  DA  DA  E . n 
F 5 34  DA  34  -1  -1  DA  DA  E . n 
G 6 1   DG  1   1   1   DG  DG  G . n 
G 6 2   DG  2   2   2   DG  DG  G . n 
G 6 3   DC  3   3   3   DC  DC  G . n 
G 6 4   DA  4   4   4   DA  DA  G . n 
G 6 5   DA  5   5   5   DA  DA  G . n 
G 6 6   DT  6   6   6   DT  DT  G . n 
G 6 7   DC  7   7   7   DC  DC  G . n 
G 6 8   DA  8   8   8   DA  DA  G . n 
G 6 9   DT  9   9   9   DT  DT  G . n 
G 6 10  DC  10  10  10  DC  DC  G . n 
G 6 11  DA  11  11  11  DA  DA  G . n 
G 6 12  DA  12  12  12  DA  DA  G . n 
G 6 13  DT  13  13  13  DT  DT  G . n 
G 6 14  DT  14  14  14  DT  DT  G . n 
G 6 15  DT  15  15  15  DT  DT  G . n 
G 6 16  DT  16  16  ?   ?   ?   G . n 
G 6 17  DT  17  17  ?   ?   ?   G . n 
G 6 18  DT  18  18  ?   ?   ?   G . n 
G 6 19  DA  19  19  ?   ?   ?   G . n 
G 6 20  DA  20  20  ?   ?   ?   G . n 
G 6 21  DC  21  21  ?   ?   ?   G . n 
G 6 22  DG  22  22  ?   ?   ?   G . n 
G 6 23  DC  23  23  ?   ?   ?   G . n 
G 6 24  DT  24  24  ?   ?   ?   G . n 
G 6 25  DG  25  25  ?   ?   ?   G . n 
G 6 26  DA  26  26  ?   ?   ?   G . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
H 7 MG 1 401 401 MG MG A . 
I 7 MG 1 402 402 MG MG A . 
J 7 MG 1 401 401 MG MG B . 
K 7 MG 1 402 402 MG MG B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MTY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MTY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MTY 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9MTY 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.05 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_struct.entry_id                     9MTY 
_struct.title                        'Structure of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MTY 
_struct_keywords.text            
'nuclease, RNA-guided, Nop domain, DNA-binding protein, DNA-RNA HYBRID, DNA BINDING PROTEIN-RNA-DNA complex' 
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN/RNA/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 4 ? 
F N N 5 ? 
G N N 6 ? 
H N N 7 ? 
I N N 7 ? 
J N N 7 ? 
K N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A370LRB3_9CREN A0A370LRB3 ? 1 
;MDNDITILAVDWSHEERKLAIFDGKKIRKKLPEPSSDVIIVAENIPQKYAAPFIEVGAKVLRCSTNATADARKNYQKKVD
AAFAKNDENDSKVIWALYQTHPELFREMKLEPPLSSYYAIFKDYQEVRIRTGNRLYSDRTDAMEEFFKIVKKGEHELKKA
VDKELENHPVYTQWLQHIKGIGPVVAGGLISLIGDIDRFDSVSKLWAYAGYSVDNGKVQKRKKGVASNWKNKIRTHCYNI
VDSFIKQRTSVYRELYDAEKARQRPKVESDGHAHNRAVRKVAKVFLQHYWVVSRELAGFSVSKPWILEHGGHVDYIKPPH
WNKVEIKPCKP
;
1 
2 PDB 9MTY             9MTY       ? 2 ? 1 
3 PDB 9MTY             9MTY       ? 3 ? 1 
4 PDB 9MTY             9MTY       ? 4 ? 1 
5 PDB 9MTY             9MTY       ? 5 ? 1 
6 PDB 9MTY             9MTY       ? 6 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9MTY A 1 ? 331 ? A0A370LRB3 1   ? 331 ? 1   331 
2 1 9MTY B 1 ? 331 ? A0A370LRB3 1   ? 331 ? 1   331 
3 2 9MTY C 1 ? 36  ? 9MTY       1   ? 36  ? 1   36  
4 3 9MTY D 1 ? 34  ? 9MTY       -34 ? -1  ? -34 -1  
5 4 9MTY F 1 ? 26  ? 9MTY       1   ? 26  ? 1   26  
6 5 9MTY E 1 ? 34  ? 9MTY       -34 ? -1  ? -34 -1  
7 6 9MTY G 1 ? 26  ? 9MTY       1   ? 26  ? 1   26  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   heptameric 
_pdbx_struct_assembly.oligomeric_count     7 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 46  ? GLU A 55  ? PRO A 46  GLU A 55  1 ? 10 
HELX_P HELX_P2  AA2 ASN A 66  ? ARG A 72  ? ASN A 66  ARG A 72  1 ? 7  
HELX_P HELX_P3  AA3 GLU A 88  ? HIS A 101 ? GLU A 88  HIS A 101 1 ? 14 
HELX_P HELX_P4  AA4 PRO A 112 ? ASP A 138 ? PRO A 112 ASP A 138 1 ? 27 
HELX_P HELX_P5  AA5 THR A 140 ? LEU A 165 ? THR A 140 LEU A 165 1 ? 26 
HELX_P HELX_P6  AA6 HIS A 168 ? GLN A 173 ? HIS A 168 GLN A 173 1 ? 6  
HELX_P HELX_P7  AA7 GLY A 182 ? GLY A 194 ? GLY A 182 GLY A 194 1 ? 13 
HELX_P HELX_P8  AA8 ASP A 195 ? PHE A 199 ? ASP A 195 PHE A 199 5 ? 5  
HELX_P HELX_P9  AA9 SER A 201 ? GLY A 210 ? SER A 201 GLY A 210 1 ? 10 
HELX_P HELX_P10 AB1 LYS A 230 ? ARG A 248 ? LYS A 230 ARG A 248 1 ? 19 
HELX_P HELX_P11 AB2 THR A 249 ? ARG A 264 ? THR A 249 ARG A 264 1 ? 16 
HELX_P HELX_P12 AB3 PRO A 265 ? VAL A 267 ? PRO A 265 VAL A 267 5 ? 3  
HELX_P HELX_P13 AB4 SER A 269 ? GLY A 298 ? SER A 269 GLY A 298 1 ? 30 
HELX_P HELX_P14 AB5 PRO B 46  ? GLU B 55  ? PRO B 46  GLU B 55  1 ? 10 
HELX_P HELX_P15 AB6 ASN B 66  ? ARG B 72  ? ASN B 66  ARG B 72  1 ? 7  
HELX_P HELX_P16 AB7 LYS B 73  ? ASN B 74  ? LYS B 73  ASN B 74  5 ? 2  
HELX_P HELX_P17 AB8 ASN B 86  ? GLU B 88  ? ASN B 86  GLU B 88  5 ? 3  
HELX_P HELX_P18 AB9 ASN B 89  ? HIS B 101 ? ASN B 89  HIS B 101 1 ? 13 
HELX_P HELX_P19 AC1 PRO B 102 ? PHE B 105 ? PRO B 102 PHE B 105 5 ? 4  
HELX_P HELX_P20 AC2 PRO B 112 ? ASP B 138 ? PRO B 112 ASP B 138 1 ? 27 
HELX_P HELX_P21 AC3 THR B 140 ? LEU B 165 ? THR B 140 LEU B 165 1 ? 26 
HELX_P HELX_P22 AC4 HIS B 168 ? GLN B 173 ? HIS B 168 GLN B 173 1 ? 6  
HELX_P HELX_P23 AC5 GLY B 182 ? GLY B 194 ? GLY B 182 GLY B 194 1 ? 13 
HELX_P HELX_P24 AC6 ASP B 195 ? PHE B 199 ? ASP B 195 PHE B 199 5 ? 5  
HELX_P HELX_P25 AC7 SER B 201 ? GLY B 210 ? SER B 201 GLY B 210 1 ? 10 
HELX_P HELX_P26 AC8 LYS B 230 ? ARG B 248 ? LYS B 230 ARG B 248 1 ? 19 
HELX_P HELX_P27 AC9 THR B 249 ? ARG B 264 ? THR B 249 ARG B 264 1 ? 16 
HELX_P HELX_P28 AD1 PRO B 265 ? VAL B 267 ? PRO B 265 VAL B 267 5 ? 3  
HELX_P HELX_P29 AD2 SER B 269 ? GLY B 298 ? SER B 269 GLY B 298 1 ? 30 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1   metalc ? ? A ASP 11  OD1 ? ? ? 1_555 H MG .  MG  ? ? A ASP 11  A MG 401 1_555 ? ? ? ? ? ? ?             2.235 ? ? 
metalc2   metalc ? ? A ASP 123 OD1 ? ? ? 1_555 I MG .  MG  ? ? A ASP 123 A MG 402 1_555 ? ? ? ? ? ? ?             2.254 ? ? 
metalc3   metalc ? ? I MG  .   MG  ? ? ? 1_555 C G  11 OP1 ? ? A MG  402 C G  11  1_555 ? ? ? ? ? ? ?             2.301 ? ? 
metalc4   metalc ? ? B ASP 11  OD1 ? ? ? 1_555 J MG .  MG  ? ? B ASP 11  B MG 401 1_555 ? ? ? ? ? ? ?             2.052 ? ? 
metalc5   metalc ? ? B ASP 11  OD2 ? ? ? 1_555 J MG .  MG  ? ? B ASP 11  B MG 401 1_555 ? ? ? ? ? ? ?             2.274 ? ? 
metalc6   metalc ? ? B ASP 123 OD1 ? ? ? 1_555 K MG .  MG  ? ? B ASP 123 B MG 402 1_555 ? ? ? ? ? ? ?             2.171 ? ? 
metalc7   metalc ? ? K MG  .   MG  ? ? ? 1_555 C U  29 OP1 ? ? B MG  402 C U  29  1_555 ? ? ? ? ? ? ?             2.186 ? ? 
hydrog1   hydrog ? ? C A   1   N6  ? ? ? 1_555 C G  36 O6  ? ? C A   1   C G  36  1_555 ? ? ? ? ? ? 'A-G MISPAIR' ?     ? ? 
hydrog2   hydrog ? ? C G   2   N1  ? ? ? 1_555 C C  35 N3  ? ? C G   2   C C  35  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog3   hydrog ? ? C G   2   N2  ? ? ? 1_555 C C  35 O2  ? ? C G   2   C C  35  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog4   hydrog ? ? C G   2   O6  ? ? ? 1_555 C C  35 N4  ? ? C G   2   C C  35  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog5   hydrog ? ? C C   3   N3  ? ? ? 1_555 C G  34 N1  ? ? C C   3   C G  34  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog6   hydrog ? ? C C   3   N4  ? ? ? 1_555 C G  34 O6  ? ? C C   3   C G  34  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog7   hydrog ? ? C C   3   O2  ? ? ? 1_555 C G  34 N2  ? ? C C   3   C G  34  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog8   hydrog ? ? C U   6   N3  ? ? ? 1_555 E DA 5  N1  ? ? C U   6   F DA 5   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog9   hydrog ? ? C U   6   O4  ? ? ? 1_555 E DA 5  N6  ? ? C U   6   F DA 5   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog10  hydrog ? ? C G   7   N1  ? ? ? 1_555 E DC 4  N3  ? ? C G   7   F DC 4   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog11  hydrog ? ? C G   7   N2  ? ? ? 1_555 E DC 4  O2  ? ? C G   7   F DC 4   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog12  hydrog ? ? C G   7   O6  ? ? ? 1_555 E DC 4  N4  ? ? C G   7   F DC 4   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog13  hydrog ? ? C C   8   N3  ? ? ? 1_555 E DG 3  N1  ? ? C C   8   F DG 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog14  hydrog ? ? C C   8   N4  ? ? ? 1_555 E DG 3  O6  ? ? C C   8   F DG 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog15  hydrog ? ? C C   8   O2  ? ? ? 1_555 E DG 3  N2  ? ? C C   8   F DG 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog16  hydrog ? ? C A   9   N1  ? ? ? 1_555 E DT 2  N3  ? ? C A   9   F DT 2   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog17  hydrog ? ? C A   9   N6  ? ? ? 1_555 E DT 2  O4  ? ? C A   9   F DT 2   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog18  hydrog ? ? C A   10  N1  ? ? ? 1_555 E DT 1  N3  ? ? C A   10  F DT 1   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog19  hydrog ? ? C A   10  N6  ? ? ? 1_555 E DT 1  O4  ? ? C A   10  F DT 1   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog20  hydrog ? ? C G   11  N1  ? ? ? 1_555 D DC 34 N3  ? ? C G   11  D DC -1  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog21  hydrog ? ? C G   11  N2  ? ? ? 1_555 D DC 34 O2  ? ? C G   11  D DC -1  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog22  hydrog ? ? C G   11  O6  ? ? ? 1_555 D DC 34 N4  ? ? C G   11  D DC -1  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog23  hydrog ? ? C C   12  N3  ? ? ? 1_555 D DG 33 N1  ? ? C C   12  D DG -2  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog24  hydrog ? ? C C   12  N4  ? ? ? 1_555 D DG 33 O6  ? ? C C   12  D DG -2  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog25  hydrog ? ? C C   12  O2  ? ? ? 1_555 D DG 33 N2  ? ? C C   12  D DG -2  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog26  hydrog ? ? C C   13  N3  ? ? ? 1_555 D DG 32 N1  ? ? C C   13  D DG -3  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog27  hydrog ? ? C C   13  N4  ? ? ? 1_555 D DG 32 O6  ? ? C C   13  D DG -3  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog28  hydrog ? ? C C   13  O2  ? ? ? 1_555 D DG 32 N2  ? ? C C   13  D DG -3  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog29  hydrog ? ? C C   14  N3  ? ? ? 1_555 D DG 31 N1  ? ? C C   14  D DG -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog30  hydrog ? ? C C   14  N4  ? ? ? 1_555 D DG 31 O6  ? ? C C   14  D DG -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog31  hydrog ? ? C C   14  O2  ? ? ? 1_555 D DG 31 N2  ? ? C C   14  D DG -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog32  hydrog ? ? C G   16  N1  ? ? ? 1_555 C C  21 N3  ? ? C G   16  C C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog33  hydrog ? ? C G   16  N2  ? ? ? 1_555 C C  21 O2  ? ? C G   16  C C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog34  hydrog ? ? C G   16  O6  ? ? ? 1_555 C C  21 N4  ? ? C G   16  C C  21  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog35  hydrog ? ? C U   24  N3  ? ? ? 1_555 G DA 5  N1  ? ? C U   24  G DA 5   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog36  hydrog ? ? C U   24  O4  ? ? ? 1_555 G DA 5  N6  ? ? C U   24  G DA 5   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog37  hydrog ? ? C U   25  N3  ? ? ? 1_555 G DA 4  N1  ? ? C U   25  G DA 4   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog38  hydrog ? ? C U   25  O4  ? ? ? 1_555 G DA 4  N6  ? ? C U   25  G DA 4   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog39  hydrog ? ? C G   26  N1  ? ? ? 1_555 G DC 3  N3  ? ? C G   26  G DC 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog40  hydrog ? ? C G   26  N2  ? ? ? 1_555 G DC 3  O2  ? ? C G   26  G DC 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog41  hydrog ? ? C G   26  O6  ? ? ? 1_555 G DC 3  N4  ? ? C G   26  G DC 3   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog42  hydrog ? ? C C   27  N3  ? ? ? 1_555 G DG 2  N1  ? ? C C   27  G DG 2   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog43  hydrog ? ? C C   27  N4  ? ? ? 1_555 G DG 2  O6  ? ? C C   27  G DG 2   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog44  hydrog ? ? C C   27  O2  ? ? ? 1_555 G DG 2  N2  ? ? C C   27  G DG 2   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog45  hydrog ? ? C C   28  N3  ? ? ? 1_555 G DG 1  N1  ? ? C C   28  G DG 1   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog46  hydrog ? ? C C   28  N4  ? ? ? 1_555 G DG 1  O6  ? ? C C   28  G DG 1   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog47  hydrog ? ? C C   28  O2  ? ? ? 1_555 G DG 1  N2  ? ? C C   28  G DG 1   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog48  hydrog ? ? C U   29  N3  ? ? ? 1_555 F DA 34 N1  ? ? C U   29  E DA -1  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog49  hydrog ? ? C U   29  O4  ? ? ? 1_555 F DA 34 N6  ? ? C U   29  E DA -1  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog50  hydrog ? ? C U   30  N3  ? ? ? 1_555 F DA 33 N1  ? ? C U   30  E DA -2  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog51  hydrog ? ? C U   30  O4  ? ? ? 1_555 F DA 33 N6  ? ? C U   30  E DA -2  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog52  hydrog ? ? C A   31  N1  ? ? ? 1_555 F DT 32 N3  ? ? C A   31  E DT -3  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog53  hydrog ? ? C A   31  N6  ? ? ? 1_555 F DT 32 O4  ? ? C A   31  E DT -3  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog54  hydrog ? ? C G   32  N1  ? ? ? 1_555 F DC 31 N3  ? ? C G   32  E DC -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog55  hydrog ? ? C G   32  N2  ? ? ? 1_555 F DC 31 O2  ? ? C G   32  E DC -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog56  hydrog ? ? C G   32  O6  ? ? ? 1_555 F DC 31 N4  ? ? C G   32  E DC -4  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog57  hydrog ? ? D DA  12  N1  ? ? ? 1_555 G DT 15 N3  ? ? D DA  -23 G DT 15  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog58  hydrog ? ? D DA  12  N6  ? ? ? 1_555 G DT 15 O4  ? ? D DA  -23 G DT 15  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog59  hydrog ? ? D DA  13  N1  ? ? ? 1_555 G DT 14 N3  ? ? D DA  -22 G DT 14  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog60  hydrog ? ? D DA  13  N6  ? ? ? 1_555 G DT 14 O4  ? ? D DA  -22 G DT 14  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog61  hydrog ? ? D DA  14  N1  ? ? ? 1_555 G DT 13 N3  ? ? D DA  -21 G DT 13  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog62  hydrog ? ? D DA  14  N6  ? ? ? 1_555 G DT 13 O4  ? ? D DA  -21 G DT 13  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog63  hydrog ? ? D DT  15  N3  ? ? ? 1_555 G DA 12 N1  ? ? D DT  -20 G DA 12  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog64  hydrog ? ? D DT  15  O4  ? ? ? 1_555 G DA 12 N6  ? ? D DT  -20 G DA 12  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog65  hydrog ? ? D DT  16  N3  ? ? ? 1_555 G DA 11 N1  ? ? D DT  -19 G DA 11  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog66  hydrog ? ? D DT  16  O4  ? ? ? 1_555 G DA 11 N6  ? ? D DT  -19 G DA 11  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog67  hydrog ? ? D DG  17  N1  ? ? ? 1_555 G DC 10 N3  ? ? D DG  -18 G DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog68  hydrog ? ? D DG  17  N2  ? ? ? 1_555 G DC 10 O2  ? ? D DG  -18 G DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog69  hydrog ? ? D DG  17  O6  ? ? ? 1_555 G DC 10 N4  ? ? D DG  -18 G DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog70  hydrog ? ? D DA  18  N1  ? ? ? 1_555 G DT 9  N3  ? ? D DA  -17 G DT 9   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog71  hydrog ? ? D DA  18  N6  ? ? ? 1_555 G DT 9  O4  ? ? D DA  -17 G DT 9   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog72  hydrog ? ? D DT  19  N3  ? ? ? 1_555 G DA 8  N1  ? ? D DT  -16 G DA 8   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog73  hydrog ? ? D DT  19  O4  ? ? ? 1_555 G DA 8  N6  ? ? D DT  -16 G DA 8   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog74  hydrog ? ? D DG  20  N1  ? ? ? 1_555 G DC 7  N3  ? ? D DG  -15 G DC 7   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog75  hydrog ? ? D DG  20  N2  ? ? ? 1_555 G DC 7  O2  ? ? D DG  -15 G DC 7   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog76  hydrog ? ? D DG  20  O6  ? ? ? 1_555 G DC 7  N4  ? ? D DG  -15 G DC 7   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog77  hydrog ? ? D DA  21  N1  ? ? ? 1_555 G DT 6  N3  ? ? D DA  -14 G DT 6   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog78  hydrog ? ? D DA  21  N6  ? ? ? 1_555 G DT 6  O4  ? ? D DA  -14 G DT 6   1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog79  hydrog ? ? E DT  6   N3  ? ? ? 1_555 F DA 21 N1  ? ? F DT  6   E DA -14 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog80  hydrog ? ? E DT  6   O4  ? ? ? 1_555 F DA 21 N6  ? ? F DT  6   E DA -14 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog81  hydrog ? ? E DC  7   N3  ? ? ? 1_555 F DG 20 N1  ? ? F DC  7   E DG -15 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog82  hydrog ? ? E DC  7   N4  ? ? ? 1_555 F DG 20 O6  ? ? F DC  7   E DG -15 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog83  hydrog ? ? E DC  7   O2  ? ? ? 1_555 F DG 20 N2  ? ? F DC  7   E DG -15 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog84  hydrog ? ? E DG  8   N1  ? ? ? 1_555 F DC 19 N3  ? ? F DG  8   E DC -16 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog85  hydrog ? ? E DG  8   N2  ? ? ? 1_555 F DC 19 O2  ? ? F DG  8   E DC -16 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog86  hydrog ? ? E DG  8   O6  ? ? ? 1_555 F DC 19 N4  ? ? F DG  8   E DC -16 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog87  hydrog ? ? E DA  9   N1  ? ? ? 1_555 F DT 18 N3  ? ? F DA  9   E DT -17 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog88  hydrog ? ? E DA  9   N6  ? ? ? 1_555 F DT 18 O4  ? ? F DA  9   E DT -17 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog89  hydrog ? ? E DA  10  N1  ? ? ? 1_555 F DT 17 N3  ? ? F DA  10  E DT -18 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog90  hydrog ? ? E DA  10  N6  ? ? ? 1_555 F DT 17 O4  ? ? F DA  10  E DT -18 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog91  hydrog ? ? E DA  11  N1  ? ? ? 1_555 F DT 16 N3  ? ? F DA  11  E DT -19 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog92  hydrog ? ? E DA  11  N6  ? ? ? 1_555 F DT 16 O4  ? ? F DA  11  E DT -19 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog93  hydrog ? ? E DC  12  N3  ? ? ? 1_555 F DG 15 N1  ? ? F DC  12  E DG -20 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog94  hydrog ? ? E DC  12  N4  ? ? ? 1_555 F DG 15 O6  ? ? F DC  12  E DG -20 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog95  hydrog ? ? E DC  12  O2  ? ? ? 1_555 F DG 15 N2  ? ? F DC  12  E DG -20 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog96  hydrog ? ? E DC  13  N3  ? ? ? 1_555 F DG 14 N1  ? ? F DC  13  E DG -21 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog97  hydrog ? ? E DC  13  N4  ? ? ? 1_555 F DG 14 O6  ? ? F DC  13  E DG -21 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog98  hydrog ? ? E DC  13  O2  ? ? ? 1_555 F DG 14 N2  ? ? F DC  13  E DG -21 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog99  hydrog ? ? E DA  14  N1  ? ? ? 1_555 F DT 13 N3  ? ? F DA  14  E DT -22 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog100 hydrog ? ? E DA  14  N6  ? ? ? 1_555 F DT 13 O4  ? ? F DA  14  E DT -22 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog101 hydrog ? ? E DC  15  N3  ? ? ? 1_555 F DG 12 N1  ? ? F DC  15  E DG -23 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog102 hydrog ? ? E DC  15  N4  ? ? ? 1_555 F DG 12 O6  ? ? F DC  15  E DG -23 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
hydrog103 hydrog ? ? E DC  15  O2  ? ? ? 1_555 F DG 12 N2  ? ? F DC  15  E DG -23 1_555 ? ? ? ? ? ? WATSON-CRICK  ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD1 ? A ASP 123 ? A ASP 123 ? 1_555 MG ? I MG . ? A MG 402 ? 1_555 OP1 ? C G   11 ? C G   11 ? 1_555 92.8  ? 
2 OD1 ? B ASP 11  ? B ASP 11  ? 1_555 MG ? J MG . ? B MG 401 ? 1_555 OD2 ? B ASP 11 ? B ASP 11 ? 1_555 60.2  ? 
3 OD1 ? B ASP 123 ? B ASP 123 ? 1_555 MG ? K MG . ? B MG 402 ? 1_555 OP1 ? C U   29 ? C U   29 ? 1_555 100.1 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 6 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 27  ? ARG A 28  ? ILE A 27  ARG A 28  
AA1 2 ALA A 20  ? PHE A 22  ? ALA A 20  PHE A 22  
AA1 3 ILE A 7   ? ASP A 11  ? ILE A 7   ASP A 11  
AA1 4 ILE A 39  ? ALA A 42  ? ILE A 39  ALA A 42  
AA1 5 LYS A 59  ? ARG A 62  ? LYS A 59  ARG A 62  
AA1 6 ARG A 106 ? GLU A 107 ? ARG A 106 GLU A 107 
AA2 1 VAL A 213 ? ASP A 214 ? VAL A 213 ASP A 214 
AA2 2 LYS A 217 ? VAL A 218 ? LYS A 217 VAL A 218 
AA3 1 ILE B 27  ? ARG B 28  ? ILE B 27  ARG B 28  
AA3 2 ALA B 20  ? PHE B 22  ? ALA B 20  PHE B 22  
AA3 3 ILE B 7   ? ASP B 11  ? ILE B 7   ASP B 11  
AA3 4 ILE B 39  ? ALA B 42  ? ILE B 39  ALA B 42  
AA3 5 VAL B 60  ? ARG B 62  ? VAL B 60  ARG B 62  
AA3 6 ARG B 106 ? GLU B 107 ? ARG B 106 GLU B 107 
AA4 1 VAL B 213 ? ASP B 214 ? VAL B 213 ASP B 214 
AA4 2 LYS B 217 ? VAL B 218 ? LYS B 217 VAL B 218 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ARG A 28  ? O ARG A 28  N ILE A 21  ? N ILE A 21  
AA1 2 3 O ALA A 20  ? O ALA A 20  N ASP A 11  ? N ASP A 11  
AA1 3 4 N VAL A 10  ? N VAL A 10  O VAL A 41  ? O VAL A 41  
AA1 4 5 N ILE A 40  ? N ILE A 40  O LYS A 59  ? O LYS A 59  
AA1 5 6 N ARG A 62  ? N ARG A 62  O ARG A 106 ? O ARG A 106 
AA2 1 2 N ASP A 214 ? N ASP A 214 O LYS A 217 ? O LYS A 217 
AA3 1 2 O ARG B 28  ? O ARG B 28  N ILE B 21  ? N ILE B 21  
AA3 2 3 O ALA B 20  ? O ALA B 20  N ASP B 11  ? N ASP B 11  
AA3 3 4 N LEU B 8   ? N LEU B 8   O ILE B 39  ? O ILE B 39  
AA3 4 5 N ILE B 40  ? N ILE B 40  O LEU B 61  ? O LEU B 61  
AA3 5 6 N ARG B 62  ? N ARG B 62  O ARG B 106 ? O ARG B 106 
AA4 1 2 N ASP B 214 ? N ASP B 214 O LYS B 217 ? O LYS B 217 
# 
_pdbx_entry_details.entry_id                   9MTY 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 "O3'" F DT 2 ? ? "C3'" F DT 2 ? ? 1.369 1.419 -0.050 0.006 N 
2 1 "O3'" F DA 5 ? ? "C3'" F DA 5 ? ? 1.373 1.419 -0.046 0.006 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 "C3'" C A  18  ? ? "O3'" C A  18  ? ? P     C A  19  ? ? 127.07 119.70 7.37  1.20 Y 
2  1 "O4'" C G  32  ? ? "C1'" C G  32  ? ? N9    C G  32  ? ? 114.47 108.50 5.97  0.70 N 
3  1 "O4'" D DA -23 ? ? "C1'" D DA -23 ? ? N9    D DA -23 ? ? 113.97 108.30 5.67  0.30 N 
4  1 "O4'" D DT -16 ? ? "C1'" D DT -16 ? ? N1    D DT -16 ? ? 111.94 108.30 3.64  0.30 N 
5  1 "O4'" D DA -14 ? ? "C1'" D DA -14 ? ? N9    D DA -14 ? ? 111.39 108.30 3.09  0.30 N 
6  1 "O4'" D DA -6  ? ? "C1'" D DA -6  ? ? N9    D DA -6  ? ? 115.23 108.30 6.93  0.30 N 
7  1 "C1'" D DG -5  ? ? "O4'" D DG -5  ? ? "C4'" D DG -5  ? ? 102.68 110.10 -7.42 1.00 N 
8  1 "C3'" D DG -5  ? ? "C2'" D DG -5  ? ? "C1'" D DG -5  ? ? 97.39  102.40 -5.01 0.80 N 
9  1 "O4'" D DG -5  ? ? "C1'" D DG -5  ? ? N9    D DG -5  ? ? 117.56 108.30 9.26  0.30 N 
10 1 "O4'" D DG -2  ? ? "C1'" D DG -2  ? ? N9    D DG -2  ? ? 110.39 108.30 2.09  0.30 N 
11 1 "O4'" F DT 1   ? ? "C1'" F DT 1   ? ? N1    F DT 1   ? ? 110.73 108.30 2.43  0.30 N 
12 1 "O4'" F DG 3   ? ? "C1'" F DG 3   ? ? N9    F DG 3   ? ? 111.41 108.30 3.11  0.30 N 
13 1 "O4'" F DC 4   ? ? "C1'" F DC 4   ? ? N1    F DC 4   ? ? 110.91 108.30 2.61  0.30 N 
14 1 "O4'" F DA 5   ? ? "C1'" F DA 5   ? ? N9    F DA 5   ? ? 110.83 108.30 2.53  0.30 N 
15 1 "O4'" F DA 14  ? ? "C1'" F DA 14  ? ? N9    F DA 14  ? ? 110.58 108.30 2.28  0.30 N 
16 1 "O4'" F DC 15  ? ? "C1'" F DC 15  ? ? N1    F DC 15  ? ? 110.83 108.30 2.53  0.30 N 
17 1 "O4'" E DG -23 ? ? "C1'" E DG -23 ? ? N9    E DG -23 ? ? 111.07 108.30 2.77  0.30 N 
18 1 "O4'" E DC -16 ? ? "C1'" E DC -16 ? ? N1    E DC -16 ? ? 111.67 108.30 3.37  0.30 N 
19 1 "O4'" E DG -12 ? ? "C1'" E DG -12 ? ? N9    E DG -12 ? ? 110.41 108.30 2.11  0.30 N 
20 1 "O4'" E DC -7  ? ? "C1'" E DC -7  ? ? N1    E DC -7  ? ? 110.38 108.30 2.08  0.30 N 
21 1 "C1'" E DC -5  ? ? "O4'" E DC -5  ? ? "C4'" E DC -5  ? ? 103.47 110.10 -6.63 1.00 N 
22 1 "O4'" E DC -5  ? ? "C1'" E DC -5  ? ? N1    E DC -5  ? ? 110.98 108.30 2.68  0.30 N 
23 1 "O4'" E DA -1  ? ? "C1'" E DA -1  ? ? N9    E DA -1  ? ? 110.28 108.30 1.98  0.30 N 
24 1 "O4'" G DG 1   ? ? "C1'" G DG 1   ? ? N9    G DG 1   ? ? 111.95 108.30 3.65  0.30 N 
25 1 "O4'" G DG 2   ? ? "C1'" G DG 2   ? ? N9    G DG 2   ? ? 110.19 108.30 1.89  0.30 N 
26 1 "O4'" G DC 3   ? ? "C1'" G DC 3   ? ? N1    G DC 3   ? ? 110.23 108.30 1.93  0.30 N 
27 1 "O4'" G DA 4   ? ? "C1'" G DA 4   ? ? N9    G DA 4   ? ? 110.15 108.30 1.85  0.30 N 
28 1 "O4'" G DA 5   ? ? "C1'" G DA 5   ? ? N9    G DA 5   ? ? 111.71 108.30 3.41  0.30 N 
29 1 "O4'" G DT 6   ? ? "C1'" G DT 6   ? ? N1    G DT 6   ? ? 113.20 108.30 4.90  0.30 N 
30 1 "O4'" G DA 11  ? ? "C1'" G DA 11  ? ? N9    G DA 11  ? ? 110.47 108.30 2.17  0.30 N 
31 1 "O4'" G DT 14  ? ? "C1'" G DT 14  ? ? N1    G DT 14  ? ? 110.51 108.30 2.21  0.30 N 
32 1 "O4'" G DT 15  ? ? "C1'" G DT 15  ? ? N1    G DT 15  ? ? 111.18 108.30 2.88  0.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LYS A 25  ? ? -137.21 -33.25  
2  1 ASN A 44  ? ? 71.61   45.66   
3  1 TRP A 174 ? ? -143.60 -66.02  
4  1 LYS A 222 ? ? -163.14 112.21  
5  1 ASN A 228 ? ? -142.19 33.89   
6  1 SER A 250 ? ? 36.58   -129.60 
7  1 LYS B 25  ? ? -136.08 -36.29  
8  1 ASN B 44  ? ? 73.28   40.86   
9  1 TRP B 174 ? ? -140.16 -64.88  
10 1 SER B 250 ? ? 29.34   -124.15 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 134 ? ? 0.073 'SIDE CHAIN' 
2 1 ARG B 130 ? ? 0.081 'SIDE CHAIN' 
3 1 ARG B 134 ? ? 0.073 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MTY 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    9MTY 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.05 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               763089 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          1 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.9 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'TIGR-TasR product complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2 
# 
_em_imaging.entry_id                        9MTY 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9MTY 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9MTY 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9MTY 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASP 2   ? A ASP 2   
3   1 Y 1 A ASN 3   ? A ASN 3   
4   1 Y 1 A ASP 4   ? A ASP 4   
5   1 Y 1 A ILE 5   ? A ILE 5   
6   1 Y 1 A TYR 75  ? A TYR 75  
7   1 Y 1 A GLN 76  ? A GLN 76  
8   1 Y 1 A LYS 77  ? A LYS 77  
9   1 Y 1 A LYS 78  ? A LYS 78  
10  1 Y 1 A VAL 79  ? A VAL 79  
11  1 Y 1 A ASP 80  ? A ASP 80  
12  1 Y 1 A ALA 81  ? A ALA 81  
13  1 Y 1 A ALA 82  ? A ALA 82  
14  1 Y 1 A PHE 83  ? A PHE 83  
15  1 Y 1 A ALA 84  ? A ALA 84  
16  1 Y 1 A LYS 85  ? A LYS 85  
17  1 Y 1 A LYS 303 ? A LYS 303 
18  1 Y 1 A PRO 304 ? A PRO 304 
19  1 Y 1 A TRP 305 ? A TRP 305 
20  1 Y 1 A ILE 306 ? A ILE 306 
21  1 Y 1 A LEU 307 ? A LEU 307 
22  1 Y 1 A GLU 308 ? A GLU 308 
23  1 Y 1 A HIS 309 ? A HIS 309 
24  1 Y 1 A GLY 310 ? A GLY 310 
25  1 Y 1 A GLY 311 ? A GLY 311 
26  1 Y 1 A HIS 312 ? A HIS 312 
27  1 Y 1 A VAL 313 ? A VAL 313 
28  1 Y 1 A ASP 314 ? A ASP 314 
29  1 Y 1 A TYR 315 ? A TYR 315 
30  1 Y 1 A ILE 316 ? A ILE 316 
31  1 Y 1 A LYS 323 ? A LYS 323 
32  1 Y 1 A VAL 324 ? A VAL 324 
33  1 Y 1 A GLU 325 ? A GLU 325 
34  1 Y 1 A ILE 326 ? A ILE 326 
35  1 Y 1 A LYS 327 ? A LYS 327 
36  1 Y 1 A PRO 328 ? A PRO 328 
37  1 Y 1 A CYS 329 ? A CYS 329 
38  1 Y 1 A LYS 330 ? A LYS 330 
39  1 Y 1 A PRO 331 ? A PRO 331 
40  1 Y 1 B MET 1   ? B MET 1   
41  1 Y 1 B ASP 2   ? B ASP 2   
42  1 Y 1 B ASN 3   ? B ASN 3   
43  1 Y 1 B ASP 4   ? B ASP 4   
44  1 Y 1 B ILE 5   ? B ILE 5   
45  1 Y 1 B TYR 75  ? B TYR 75  
46  1 Y 1 B GLN 76  ? B GLN 76  
47  1 Y 1 B LYS 77  ? B LYS 77  
48  1 Y 1 B LYS 78  ? B LYS 78  
49  1 Y 1 B VAL 79  ? B VAL 79  
50  1 Y 1 B ASP 80  ? B ASP 80  
51  1 Y 1 B ALA 81  ? B ALA 81  
52  1 Y 1 B ALA 82  ? B ALA 82  
53  1 Y 1 B PHE 83  ? B PHE 83  
54  1 Y 1 B ALA 84  ? B ALA 84  
55  1 Y 1 B LYS 85  ? B LYS 85  
56  1 Y 1 B PRO 304 ? B PRO 304 
57  1 Y 1 B TRP 305 ? B TRP 305 
58  1 Y 1 B ILE 306 ? B ILE 306 
59  1 Y 1 B LEU 307 ? B LEU 307 
60  1 Y 1 B GLU 308 ? B GLU 308 
61  1 Y 1 B HIS 309 ? B HIS 309 
62  1 Y 1 B GLY 310 ? B GLY 310 
63  1 Y 1 B GLY 311 ? B GLY 311 
64  1 Y 1 B HIS 312 ? B HIS 312 
65  1 Y 1 B VAL 313 ? B VAL 313 
66  1 Y 1 B ASP 314 ? B ASP 314 
67  1 Y 1 B TYR 315 ? B TYR 315 
68  1 Y 1 B LYS 323 ? B LYS 323 
69  1 Y 1 B VAL 324 ? B VAL 324 
70  1 Y 1 B GLU 325 ? B GLU 325 
71  1 Y 1 B ILE 326 ? B ILE 326 
72  1 Y 1 B LYS 327 ? B LYS 327 
73  1 Y 1 B PRO 328 ? B PRO 328 
74  1 Y 1 B CYS 329 ? B CYS 329 
75  1 Y 1 B LYS 330 ? B LYS 330 
76  1 Y 1 B PRO 331 ? B PRO 331 
77  1 Y 1 D DT  -34 ? D DT  1   
78  1 Y 1 D DC  -33 ? D DC  2   
79  1 Y 1 D DA  -32 ? D DA  3   
80  1 Y 1 D DG  -31 ? D DG  4   
81  1 Y 1 D DC  -30 ? D DC  5   
82  1 Y 1 D DG  -29 ? D DG  6   
83  1 Y 1 D DT  -28 ? D DT  7   
84  1 Y 1 D DT  -27 ? D DT  8   
85  1 Y 1 D DA  -26 ? D DA  9   
86  1 Y 1 D DA  -25 ? D DA  10  
87  1 Y 1 D DA  -24 ? D DA  11  
88  1 Y 1 F DA  16  ? E DA  16  
89  1 Y 1 F DG  17  ? E DG  17  
90  1 Y 1 F DC  18  ? E DC  18  
91  1 Y 1 F DC  19  ? E DC  19  
92  1 Y 1 F DA  20  ? E DA  20  
93  1 Y 1 F DA  21  ? E DA  21  
94  1 Y 1 F DG  22  ? E DG  22  
95  1 Y 1 F DG  23  ? E DG  23  
96  1 Y 1 F DG  24  ? E DG  24  
97  1 Y 1 F DA  25  ? E DA  25  
98  1 Y 1 F DA  26  ? E DA  26  
99  1 Y 1 E DT  -34 ? F DT  1   
100 1 Y 1 E DT  -33 ? F DT  2   
101 1 Y 1 E DC  -32 ? F DC  3   
102 1 Y 1 E DC  -31 ? F DC  4   
103 1 Y 1 E DC  -30 ? F DC  5   
104 1 Y 1 E DT  -29 ? F DT  6   
105 1 Y 1 E DT  -28 ? F DT  7   
106 1 Y 1 E DG  -27 ? F DG  8   
107 1 Y 1 E DG  -26 ? F DG  9   
108 1 Y 1 E DC  -25 ? F DC  10  
109 1 Y 1 E DT  -24 ? F DT  11  
110 1 Y 1 G DT  16  ? G DT  16  
111 1 Y 1 G DT  17  ? G DT  17  
112 1 Y 1 G DT  18  ? G DT  18  
113 1 Y 1 G DA  19  ? G DA  19  
114 1 Y 1 G DA  20  ? G DA  20  
115 1 Y 1 G DC  21  ? G DC  21  
116 1 Y 1 G DG  22  ? G DG  22  
117 1 Y 1 G DC  23  ? G DC  23  
118 1 Y 1 G DT  24  ? G DT  24  
119 1 Y 1 G DG  25  ? G DG  25  
120 1 Y 1 G DA  26  ? G DA  26  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O  N N 1   
A   P      P  N N 2   
A   OP1    O  N N 3   
A   OP2    O  N N 4   
A   "O5'"  O  N N 5   
A   "C5'"  C  N N 6   
A   "C4'"  C  N R 7   
A   "O4'"  O  N N 8   
A   "C3'"  C  N S 9   
A   "O3'"  O  N N 10  
A   "C2'"  C  N R 11  
A   "O2'"  O  N N 12  
A   "C1'"  C  N R 13  
A   N9     N  Y N 14  
A   C8     C  Y N 15  
A   N7     N  Y N 16  
A   C5     C  Y N 17  
A   C6     C  Y N 18  
A   N6     N  N N 19  
A   N1     N  Y N 20  
A   C2     C  Y N 21  
A   N3     N  Y N 22  
A   C4     C  Y N 23  
A   HOP3   H  N N 24  
A   HOP2   H  N N 25  
A   "H5'"  H  N N 26  
A   "H5''" H  N N 27  
A   "H4'"  H  N N 28  
A   "H3'"  H  N N 29  
A   "HO3'" H  N N 30  
A   "H2'"  H  N N 31  
A   "HO2'" H  N N 32  
A   "H1'"  H  N N 33  
A   H8     H  N N 34  
A   H61    H  N N 35  
A   H62    H  N N 36  
A   H2     H  N N 37  
ALA N      N  N N 38  
ALA CA     C  N S 39  
ALA C      C  N N 40  
ALA O      O  N N 41  
ALA CB     C  N N 42  
ALA OXT    O  N N 43  
ALA H      H  N N 44  
ALA H2     H  N N 45  
ALA HA     H  N N 46  
ALA HB1    H  N N 47  
ALA HB2    H  N N 48  
ALA HB3    H  N N 49  
ALA HXT    H  N N 50  
ARG N      N  N N 51  
ARG CA     C  N S 52  
ARG C      C  N N 53  
ARG O      O  N N 54  
ARG CB     C  N N 55  
ARG CG     C  N N 56  
ARG CD     C  N N 57  
ARG NE     N  N N 58  
ARG CZ     C  N N 59  
ARG NH1    N  N N 60  
ARG NH2    N  N N 61  
ARG OXT    O  N N 62  
ARG H      H  N N 63  
ARG H2     H  N N 64  
ARG HA     H  N N 65  
ARG HB2    H  N N 66  
ARG HB3    H  N N 67  
ARG HG2    H  N N 68  
ARG HG3    H  N N 69  
ARG HD2    H  N N 70  
ARG HD3    H  N N 71  
ARG HE     H  N N 72  
ARG HH11   H  N N 73  
ARG HH12   H  N N 74  
ARG HH21   H  N N 75  
ARG HH22   H  N N 76  
ARG HXT    H  N N 77  
ASN N      N  N N 78  
ASN CA     C  N S 79  
ASN C      C  N N 80  
ASN O      O  N N 81  
ASN CB     C  N N 82  
ASN CG     C  N N 83  
ASN OD1    O  N N 84  
ASN ND2    N  N N 85  
ASN OXT    O  N N 86  
ASN H      H  N N 87  
ASN H2     H  N N 88  
ASN HA     H  N N 89  
ASN HB2    H  N N 90  
ASN HB3    H  N N 91  
ASN HD21   H  N N 92  
ASN HD22   H  N N 93  
ASN HXT    H  N N 94  
ASP N      N  N N 95  
ASP CA     C  N S 96  
ASP C      C  N N 97  
ASP O      O  N N 98  
ASP CB     C  N N 99  
ASP CG     C  N N 100 
ASP OD1    O  N N 101 
ASP OD2    O  N N 102 
ASP OXT    O  N N 103 
ASP H      H  N N 104 
ASP H2     H  N N 105 
ASP HA     H  N N 106 
ASP HB2    H  N N 107 
ASP HB3    H  N N 108 
ASP HD2    H  N N 109 
ASP HXT    H  N N 110 
C   OP3    O  N N 111 
C   P      P  N N 112 
C   OP1    O  N N 113 
C   OP2    O  N N 114 
C   "O5'"  O  N N 115 
C   "C5'"  C  N N 116 
C   "C4'"  C  N R 117 
C   "O4'"  O  N N 118 
C   "C3'"  C  N S 119 
C   "O3'"  O  N N 120 
C   "C2'"  C  N R 121 
C   "O2'"  O  N N 122 
C   "C1'"  C  N R 123 
C   N1     N  N N 124 
C   C2     C  N N 125 
C   O2     O  N N 126 
C   N3     N  N N 127 
C   C4     C  N N 128 
C   N4     N  N N 129 
C   C5     C  N N 130 
C   C6     C  N N 131 
C   HOP3   H  N N 132 
C   HOP2   H  N N 133 
C   "H5'"  H  N N 134 
C   "H5''" H  N N 135 
C   "H4'"  H  N N 136 
C   "H3'"  H  N N 137 
C   "HO3'" H  N N 138 
C   "H2'"  H  N N 139 
C   "HO2'" H  N N 140 
C   "H1'"  H  N N 141 
C   H41    H  N N 142 
C   H42    H  N N 143 
C   H5     H  N N 144 
C   H6     H  N N 145 
CYS N      N  N N 146 
CYS CA     C  N R 147 
CYS C      C  N N 148 
CYS O      O  N N 149 
CYS CB     C  N N 150 
CYS SG     S  N N 151 
CYS OXT    O  N N 152 
CYS H      H  N N 153 
CYS H2     H  N N 154 
CYS HA     H  N N 155 
CYS HB2    H  N N 156 
CYS HB3    H  N N 157 
CYS HG     H  N N 158 
CYS HXT    H  N N 159 
DA  OP3    O  N N 160 
DA  P      P  N N 161 
DA  OP1    O  N N 162 
DA  OP2    O  N N 163 
DA  "O5'"  O  N N 164 
DA  "C5'"  C  N N 165 
DA  "C4'"  C  N R 166 
DA  "O4'"  O  N N 167 
DA  "C3'"  C  N S 168 
DA  "O3'"  O  N N 169 
DA  "C2'"  C  N N 170 
DA  "C1'"  C  N R 171 
DA  N9     N  Y N 172 
DA  C8     C  Y N 173 
DA  N7     N  Y N 174 
DA  C5     C  Y N 175 
DA  C6     C  Y N 176 
DA  N6     N  N N 177 
DA  N1     N  Y N 178 
DA  C2     C  Y N 179 
DA  N3     N  Y N 180 
DA  C4     C  Y N 181 
DA  HOP3   H  N N 182 
DA  HOP2   H  N N 183 
DA  "H5'"  H  N N 184 
DA  "H5''" H  N N 185 
DA  "H4'"  H  N N 186 
DA  "H3'"  H  N N 187 
DA  "HO3'" H  N N 188 
DA  "H2'"  H  N N 189 
DA  "H2''" H  N N 190 
DA  "H1'"  H  N N 191 
DA  H8     H  N N 192 
DA  H61    H  N N 193 
DA  H62    H  N N 194 
DA  H2     H  N N 195 
DC  OP3    O  N N 196 
DC  P      P  N N 197 
DC  OP1    O  N N 198 
DC  OP2    O  N N 199 
DC  "O5'"  O  N N 200 
DC  "C5'"  C  N N 201 
DC  "C4'"  C  N R 202 
DC  "O4'"  O  N N 203 
DC  "C3'"  C  N S 204 
DC  "O3'"  O  N N 205 
DC  "C2'"  C  N N 206 
DC  "C1'"  C  N R 207 
DC  N1     N  N N 208 
DC  C2     C  N N 209 
DC  O2     O  N N 210 
DC  N3     N  N N 211 
DC  C4     C  N N 212 
DC  N4     N  N N 213 
DC  C5     C  N N 214 
DC  C6     C  N N 215 
DC  HOP3   H  N N 216 
DC  HOP2   H  N N 217 
DC  "H5'"  H  N N 218 
DC  "H5''" H  N N 219 
DC  "H4'"  H  N N 220 
DC  "H3'"  H  N N 221 
DC  "HO3'" H  N N 222 
DC  "H2'"  H  N N 223 
DC  "H2''" H  N N 224 
DC  "H1'"  H  N N 225 
DC  H41    H  N N 226 
DC  H42    H  N N 227 
DC  H5     H  N N 228 
DC  H6     H  N N 229 
DG  OP3    O  N N 230 
DG  P      P  N N 231 
DG  OP1    O  N N 232 
DG  OP2    O  N N 233 
DG  "O5'"  O  N N 234 
DG  "C5'"  C  N N 235 
DG  "C4'"  C  N R 236 
DG  "O4'"  O  N N 237 
DG  "C3'"  C  N S 238 
DG  "O3'"  O  N N 239 
DG  "C2'"  C  N N 240 
DG  "C1'"  C  N R 241 
DG  N9     N  Y N 242 
DG  C8     C  Y N 243 
DG  N7     N  Y N 244 
DG  C5     C  Y N 245 
DG  C6     C  N N 246 
DG  O6     O  N N 247 
DG  N1     N  N N 248 
DG  C2     C  N N 249 
DG  N2     N  N N 250 
DG  N3     N  N N 251 
DG  C4     C  Y N 252 
DG  HOP3   H  N N 253 
DG  HOP2   H  N N 254 
DG  "H5'"  H  N N 255 
DG  "H5''" H  N N 256 
DG  "H4'"  H  N N 257 
DG  "H3'"  H  N N 258 
DG  "HO3'" H  N N 259 
DG  "H2'"  H  N N 260 
DG  "H2''" H  N N 261 
DG  "H1'"  H  N N 262 
DG  H8     H  N N 263 
DG  H1     H  N N 264 
DG  H21    H  N N 265 
DG  H22    H  N N 266 
DT  OP3    O  N N 267 
DT  P      P  N N 268 
DT  OP1    O  N N 269 
DT  OP2    O  N N 270 
DT  "O5'"  O  N N 271 
DT  "C5'"  C  N N 272 
DT  "C4'"  C  N R 273 
DT  "O4'"  O  N N 274 
DT  "C3'"  C  N S 275 
DT  "O3'"  O  N N 276 
DT  "C2'"  C  N N 277 
DT  "C1'"  C  N R 278 
DT  N1     N  N N 279 
DT  C2     C  N N 280 
DT  O2     O  N N 281 
DT  N3     N  N N 282 
DT  C4     C  N N 283 
DT  O4     O  N N 284 
DT  C5     C  N N 285 
DT  C7     C  N N 286 
DT  C6     C  N N 287 
DT  HOP3   H  N N 288 
DT  HOP2   H  N N 289 
DT  "H5'"  H  N N 290 
DT  "H5''" H  N N 291 
DT  "H4'"  H  N N 292 
DT  "H3'"  H  N N 293 
DT  "HO3'" H  N N 294 
DT  "H2'"  H  N N 295 
DT  "H2''" H  N N 296 
DT  "H1'"  H  N N 297 
DT  H3     H  N N 298 
DT  H71    H  N N 299 
DT  H72    H  N N 300 
DT  H73    H  N N 301 
DT  H6     H  N N 302 
G   OP3    O  N N 303 
G   P      P  N N 304 
G   OP1    O  N N 305 
G   OP2    O  N N 306 
G   "O5'"  O  N N 307 
G   "C5'"  C  N N 308 
G   "C4'"  C  N R 309 
G   "O4'"  O  N N 310 
G   "C3'"  C  N S 311 
G   "O3'"  O  N N 312 
G   "C2'"  C  N R 313 
G   "O2'"  O  N N 314 
G   "C1'"  C  N R 315 
G   N9     N  Y N 316 
G   C8     C  Y N 317 
G   N7     N  Y N 318 
G   C5     C  Y N 319 
G   C6     C  N N 320 
G   O6     O  N N 321 
G   N1     N  N N 322 
G   C2     C  N N 323 
G   N2     N  N N 324 
G   N3     N  N N 325 
G   C4     C  Y N 326 
G   HOP3   H  N N 327 
G   HOP2   H  N N 328 
G   "H5'"  H  N N 329 
G   "H5''" H  N N 330 
G   "H4'"  H  N N 331 
G   "H3'"  H  N N 332 
G   "HO3'" H  N N 333 
G   "H2'"  H  N N 334 
G   "HO2'" H  N N 335 
G   "H1'"  H  N N 336 
G   H8     H  N N 337 
G   H1     H  N N 338 
G   H21    H  N N 339 
G   H22    H  N N 340 
GLN N      N  N N 341 
GLN CA     C  N S 342 
GLN C      C  N N 343 
GLN O      O  N N 344 
GLN CB     C  N N 345 
GLN CG     C  N N 346 
GLN CD     C  N N 347 
GLN OE1    O  N N 348 
GLN NE2    N  N N 349 
GLN OXT    O  N N 350 
GLN H      H  N N 351 
GLN H2     H  N N 352 
GLN HA     H  N N 353 
GLN HB2    H  N N 354 
GLN HB3    H  N N 355 
GLN HG2    H  N N 356 
GLN HG3    H  N N 357 
GLN HE21   H  N N 358 
GLN HE22   H  N N 359 
GLN HXT    H  N N 360 
GLU N      N  N N 361 
GLU CA     C  N S 362 
GLU C      C  N N 363 
GLU O      O  N N 364 
GLU CB     C  N N 365 
GLU CG     C  N N 366 
GLU CD     C  N N 367 
GLU OE1    O  N N 368 
GLU OE2    O  N N 369 
GLU OXT    O  N N 370 
GLU H      H  N N 371 
GLU H2     H  N N 372 
GLU HA     H  N N 373 
GLU HB2    H  N N 374 
GLU HB3    H  N N 375 
GLU HG2    H  N N 376 
GLU HG3    H  N N 377 
GLU HE2    H  N N 378 
GLU HXT    H  N N 379 
GLY N      N  N N 380 
GLY CA     C  N N 381 
GLY C      C  N N 382 
GLY O      O  N N 383 
GLY OXT    O  N N 384 
GLY H      H  N N 385 
GLY H2     H  N N 386 
GLY HA2    H  N N 387 
GLY HA3    H  N N 388 
GLY HXT    H  N N 389 
HIS N      N  N N 390 
HIS CA     C  N S 391 
HIS C      C  N N 392 
HIS O      O  N N 393 
HIS CB     C  N N 394 
HIS CG     C  Y N 395 
HIS ND1    N  Y N 396 
HIS CD2    C  Y N 397 
HIS CE1    C  Y N 398 
HIS NE2    N  Y N 399 
HIS OXT    O  N N 400 
HIS H      H  N N 401 
HIS H2     H  N N 402 
HIS HA     H  N N 403 
HIS HB2    H  N N 404 
HIS HB3    H  N N 405 
HIS HD1    H  N N 406 
HIS HD2    H  N N 407 
HIS HE1    H  N N 408 
HIS HE2    H  N N 409 
HIS HXT    H  N N 410 
ILE N      N  N N 411 
ILE CA     C  N S 412 
ILE C      C  N N 413 
ILE O      O  N N 414 
ILE CB     C  N S 415 
ILE CG1    C  N N 416 
ILE CG2    C  N N 417 
ILE CD1    C  N N 418 
ILE OXT    O  N N 419 
ILE H      H  N N 420 
ILE H2     H  N N 421 
ILE HA     H  N N 422 
ILE HB     H  N N 423 
ILE HG12   H  N N 424 
ILE HG13   H  N N 425 
ILE HG21   H  N N 426 
ILE HG22   H  N N 427 
ILE HG23   H  N N 428 
ILE HD11   H  N N 429 
ILE HD12   H  N N 430 
ILE HD13   H  N N 431 
ILE HXT    H  N N 432 
LEU N      N  N N 433 
LEU CA     C  N S 434 
LEU C      C  N N 435 
LEU O      O  N N 436 
LEU CB     C  N N 437 
LEU CG     C  N N 438 
LEU CD1    C  N N 439 
LEU CD2    C  N N 440 
LEU OXT    O  N N 441 
LEU H      H  N N 442 
LEU H2     H  N N 443 
LEU HA     H  N N 444 
LEU HB2    H  N N 445 
LEU HB3    H  N N 446 
LEU HG     H  N N 447 
LEU HD11   H  N N 448 
LEU HD12   H  N N 449 
LEU HD13   H  N N 450 
LEU HD21   H  N N 451 
LEU HD22   H  N N 452 
LEU HD23   H  N N 453 
LEU HXT    H  N N 454 
LYS N      N  N N 455 
LYS CA     C  N S 456 
LYS C      C  N N 457 
LYS O      O  N N 458 
LYS CB     C  N N 459 
LYS CG     C  N N 460 
LYS CD     C  N N 461 
LYS CE     C  N N 462 
LYS NZ     N  N N 463 
LYS OXT    O  N N 464 
LYS H      H  N N 465 
LYS H2     H  N N 466 
LYS HA     H  N N 467 
LYS HB2    H  N N 468 
LYS HB3    H  N N 469 
LYS HG2    H  N N 470 
LYS HG3    H  N N 471 
LYS HD2    H  N N 472 
LYS HD3    H  N N 473 
LYS HE2    H  N N 474 
LYS HE3    H  N N 475 
LYS HZ1    H  N N 476 
LYS HZ2    H  N N 477 
LYS HZ3    H  N N 478 
LYS HXT    H  N N 479 
MET N      N  N N 480 
MET CA     C  N S 481 
MET C      C  N N 482 
MET O      O  N N 483 
MET CB     C  N N 484 
MET CG     C  N N 485 
MET SD     S  N N 486 
MET CE     C  N N 487 
MET OXT    O  N N 488 
MET H      H  N N 489 
MET H2     H  N N 490 
MET HA     H  N N 491 
MET HB2    H  N N 492 
MET HB3    H  N N 493 
MET HG2    H  N N 494 
MET HG3    H  N N 495 
MET HE1    H  N N 496 
MET HE2    H  N N 497 
MET HE3    H  N N 498 
MET HXT    H  N N 499 
MG  MG     MG N N 500 
PHE N      N  N N 501 
PHE CA     C  N S 502 
PHE C      C  N N 503 
PHE O      O  N N 504 
PHE CB     C  N N 505 
PHE CG     C  Y N 506 
PHE CD1    C  Y N 507 
PHE CD2    C  Y N 508 
PHE CE1    C  Y N 509 
PHE CE2    C  Y N 510 
PHE CZ     C  Y N 511 
PHE OXT    O  N N 512 
PHE H      H  N N 513 
PHE H2     H  N N 514 
PHE HA     H  N N 515 
PHE HB2    H  N N 516 
PHE HB3    H  N N 517 
PHE HD1    H  N N 518 
PHE HD2    H  N N 519 
PHE HE1    H  N N 520 
PHE HE2    H  N N 521 
PHE HZ     H  N N 522 
PHE HXT    H  N N 523 
PRO N      N  N N 524 
PRO CA     C  N S 525 
PRO C      C  N N 526 
PRO O      O  N N 527 
PRO CB     C  N N 528 
PRO CG     C  N N 529 
PRO CD     C  N N 530 
PRO OXT    O  N N 531 
PRO H      H  N N 532 
PRO HA     H  N N 533 
PRO HB2    H  N N 534 
PRO HB3    H  N N 535 
PRO HG2    H  N N 536 
PRO HG3    H  N N 537 
PRO HD2    H  N N 538 
PRO HD3    H  N N 539 
PRO HXT    H  N N 540 
SER N      N  N N 541 
SER CA     C  N S 542 
SER C      C  N N 543 
SER O      O  N N 544 
SER CB     C  N N 545 
SER OG     O  N N 546 
SER OXT    O  N N 547 
SER H      H  N N 548 
SER H2     H  N N 549 
SER HA     H  N N 550 
SER HB2    H  N N 551 
SER HB3    H  N N 552 
SER HG     H  N N 553 
SER HXT    H  N N 554 
THR N      N  N N 555 
THR CA     C  N S 556 
THR C      C  N N 557 
THR O      O  N N 558 
THR CB     C  N R 559 
THR OG1    O  N N 560 
THR CG2    C  N N 561 
THR OXT    O  N N 562 
THR H      H  N N 563 
THR H2     H  N N 564 
THR HA     H  N N 565 
THR HB     H  N N 566 
THR HG1    H  N N 567 
THR HG21   H  N N 568 
THR HG22   H  N N 569 
THR HG23   H  N N 570 
THR HXT    H  N N 571 
TRP N      N  N N 572 
TRP CA     C  N S 573 
TRP C      C  N N 574 
TRP O      O  N N 575 
TRP CB     C  N N 576 
TRP CG     C  Y N 577 
TRP CD1    C  Y N 578 
TRP CD2    C  Y N 579 
TRP NE1    N  Y N 580 
TRP CE2    C  Y N 581 
TRP CE3    C  Y N 582 
TRP CZ2    C  Y N 583 
TRP CZ3    C  Y N 584 
TRP CH2    C  Y N 585 
TRP OXT    O  N N 586 
TRP H      H  N N 587 
TRP H2     H  N N 588 
TRP HA     H  N N 589 
TRP HB2    H  N N 590 
TRP HB3    H  N N 591 
TRP HD1    H  N N 592 
TRP HE1    H  N N 593 
TRP HE3    H  N N 594 
TRP HZ2    H  N N 595 
TRP HZ3    H  N N 596 
TRP HH2    H  N N 597 
TRP HXT    H  N N 598 
TYR N      N  N N 599 
TYR CA     C  N S 600 
TYR C      C  N N 601 
TYR O      O  N N 602 
TYR CB     C  N N 603 
TYR CG     C  Y N 604 
TYR CD1    C  Y N 605 
TYR CD2    C  Y N 606 
TYR CE1    C  Y N 607 
TYR CE2    C  Y N 608 
TYR CZ     C  Y N 609 
TYR OH     O  N N 610 
TYR OXT    O  N N 611 
TYR H      H  N N 612 
TYR H2     H  N N 613 
TYR HA     H  N N 614 
TYR HB2    H  N N 615 
TYR HB3    H  N N 616 
TYR HD1    H  N N 617 
TYR HD2    H  N N 618 
TYR HE1    H  N N 619 
TYR HE2    H  N N 620 
TYR HH     H  N N 621 
TYR HXT    H  N N 622 
U   OP3    O  N N 623 
U   P      P  N N 624 
U   OP1    O  N N 625 
U   OP2    O  N N 626 
U   "O5'"  O  N N 627 
U   "C5'"  C  N N 628 
U   "C4'"  C  N R 629 
U   "O4'"  O  N N 630 
U   "C3'"  C  N S 631 
U   "O3'"  O  N N 632 
U   "C2'"  C  N R 633 
U   "O2'"  O  N N 634 
U   "C1'"  C  N R 635 
U   N1     N  N N 636 
U   C2     C  N N 637 
U   O2     O  N N 638 
U   N3     N  N N 639 
U   C4     C  N N 640 
U   O4     O  N N 641 
U   C5     C  N N 642 
U   C6     C  N N 643 
U   HOP3   H  N N 644 
U   HOP2   H  N N 645 
U   "H5'"  H  N N 646 
U   "H5''" H  N N 647 
U   "H4'"  H  N N 648 
U   "H3'"  H  N N 649 
U   "HO3'" H  N N 650 
U   "H2'"  H  N N 651 
U   "HO2'" H  N N 652 
U   "H1'"  H  N N 653 
U   H3     H  N N 654 
U   H5     H  N N 655 
U   H6     H  N N 656 
VAL N      N  N N 657 
VAL CA     C  N S 658 
VAL C      C  N N 659 
VAL O      O  N N 660 
VAL CB     C  N N 661 
VAL CG1    C  N N 662 
VAL CG2    C  N N 663 
VAL OXT    O  N N 664 
VAL H      H  N N 665 
VAL H2     H  N N 666 
VAL HA     H  N N 667 
VAL HB     H  N N 668 
VAL HG11   H  N N 669 
VAL HG12   H  N N 670 
VAL HG13   H  N N 671 
VAL HG21   H  N N 672 
VAL HG22   H  N N 673 
VAL HG23   H  N N 674 
VAL HXT    H  N N 675 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
DA  OP3   P      sing N N 158 
DA  OP3   HOP3   sing N N 159 
DA  P     OP1    doub N N 160 
DA  P     OP2    sing N N 161 
DA  P     "O5'"  sing N N 162 
DA  OP2   HOP2   sing N N 163 
DA  "O5'" "C5'"  sing N N 164 
DA  "C5'" "C4'"  sing N N 165 
DA  "C5'" "H5'"  sing N N 166 
DA  "C5'" "H5''" sing N N 167 
DA  "C4'" "O4'"  sing N N 168 
DA  "C4'" "C3'"  sing N N 169 
DA  "C4'" "H4'"  sing N N 170 
DA  "O4'" "C1'"  sing N N 171 
DA  "C3'" "O3'"  sing N N 172 
DA  "C3'" "C2'"  sing N N 173 
DA  "C3'" "H3'"  sing N N 174 
DA  "O3'" "HO3'" sing N N 175 
DA  "C2'" "C1'"  sing N N 176 
DA  "C2'" "H2'"  sing N N 177 
DA  "C2'" "H2''" sing N N 178 
DA  "C1'" N9     sing N N 179 
DA  "C1'" "H1'"  sing N N 180 
DA  N9    C8     sing Y N 181 
DA  N9    C4     sing Y N 182 
DA  C8    N7     doub Y N 183 
DA  C8    H8     sing N N 184 
DA  N7    C5     sing Y N 185 
DA  C5    C6     sing Y N 186 
DA  C5    C4     doub Y N 187 
DA  C6    N6     sing N N 188 
DA  C6    N1     doub Y N 189 
DA  N6    H61    sing N N 190 
DA  N6    H62    sing N N 191 
DA  N1    C2     sing Y N 192 
DA  C2    N3     doub Y N 193 
DA  C2    H2     sing N N 194 
DA  N3    C4     sing Y N 195 
DC  OP3   P      sing N N 196 
DC  OP3   HOP3   sing N N 197 
DC  P     OP1    doub N N 198 
DC  P     OP2    sing N N 199 
DC  P     "O5'"  sing N N 200 
DC  OP2   HOP2   sing N N 201 
DC  "O5'" "C5'"  sing N N 202 
DC  "C5'" "C4'"  sing N N 203 
DC  "C5'" "H5'"  sing N N 204 
DC  "C5'" "H5''" sing N N 205 
DC  "C4'" "O4'"  sing N N 206 
DC  "C4'" "C3'"  sing N N 207 
DC  "C4'" "H4'"  sing N N 208 
DC  "O4'" "C1'"  sing N N 209 
DC  "C3'" "O3'"  sing N N 210 
DC  "C3'" "C2'"  sing N N 211 
DC  "C3'" "H3'"  sing N N 212 
DC  "O3'" "HO3'" sing N N 213 
DC  "C2'" "C1'"  sing N N 214 
DC  "C2'" "H2'"  sing N N 215 
DC  "C2'" "H2''" sing N N 216 
DC  "C1'" N1     sing N N 217 
DC  "C1'" "H1'"  sing N N 218 
DC  N1    C2     sing N N 219 
DC  N1    C6     sing N N 220 
DC  C2    O2     doub N N 221 
DC  C2    N3     sing N N 222 
DC  N3    C4     doub N N 223 
DC  C4    N4     sing N N 224 
DC  C4    C5     sing N N 225 
DC  N4    H41    sing N N 226 
DC  N4    H42    sing N N 227 
DC  C5    C6     doub N N 228 
DC  C5    H5     sing N N 229 
DC  C6    H6     sing N N 230 
DG  OP3   P      sing N N 231 
DG  OP3   HOP3   sing N N 232 
DG  P     OP1    doub N N 233 
DG  P     OP2    sing N N 234 
DG  P     "O5'"  sing N N 235 
DG  OP2   HOP2   sing N N 236 
DG  "O5'" "C5'"  sing N N 237 
DG  "C5'" "C4'"  sing N N 238 
DG  "C5'" "H5'"  sing N N 239 
DG  "C5'" "H5''" sing N N 240 
DG  "C4'" "O4'"  sing N N 241 
DG  "C4'" "C3'"  sing N N 242 
DG  "C4'" "H4'"  sing N N 243 
DG  "O4'" "C1'"  sing N N 244 
DG  "C3'" "O3'"  sing N N 245 
DG  "C3'" "C2'"  sing N N 246 
DG  "C3'" "H3'"  sing N N 247 
DG  "O3'" "HO3'" sing N N 248 
DG  "C2'" "C1'"  sing N N 249 
DG  "C2'" "H2'"  sing N N 250 
DG  "C2'" "H2''" sing N N 251 
DG  "C1'" N9     sing N N 252 
DG  "C1'" "H1'"  sing N N 253 
DG  N9    C8     sing Y N 254 
DG  N9    C4     sing Y N 255 
DG  C8    N7     doub Y N 256 
DG  C8    H8     sing N N 257 
DG  N7    C5     sing Y N 258 
DG  C5    C6     sing N N 259 
DG  C5    C4     doub Y N 260 
DG  C6    O6     doub N N 261 
DG  C6    N1     sing N N 262 
DG  N1    C2     sing N N 263 
DG  N1    H1     sing N N 264 
DG  C2    N2     sing N N 265 
DG  C2    N3     doub N N 266 
DG  N2    H21    sing N N 267 
DG  N2    H22    sing N N 268 
DG  N3    C4     sing N N 269 
DT  OP3   P      sing N N 270 
DT  OP3   HOP3   sing N N 271 
DT  P     OP1    doub N N 272 
DT  P     OP2    sing N N 273 
DT  P     "O5'"  sing N N 274 
DT  OP2   HOP2   sing N N 275 
DT  "O5'" "C5'"  sing N N 276 
DT  "C5'" "C4'"  sing N N 277 
DT  "C5'" "H5'"  sing N N 278 
DT  "C5'" "H5''" sing N N 279 
DT  "C4'" "O4'"  sing N N 280 
DT  "C4'" "C3'"  sing N N 281 
DT  "C4'" "H4'"  sing N N 282 
DT  "O4'" "C1'"  sing N N 283 
DT  "C3'" "O3'"  sing N N 284 
DT  "C3'" "C2'"  sing N N 285 
DT  "C3'" "H3'"  sing N N 286 
DT  "O3'" "HO3'" sing N N 287 
DT  "C2'" "C1'"  sing N N 288 
DT  "C2'" "H2'"  sing N N 289 
DT  "C2'" "H2''" sing N N 290 
DT  "C1'" N1     sing N N 291 
DT  "C1'" "H1'"  sing N N 292 
DT  N1    C2     sing N N 293 
DT  N1    C6     sing N N 294 
DT  C2    O2     doub N N 295 
DT  C2    N3     sing N N 296 
DT  N3    C4     sing N N 297 
DT  N3    H3     sing N N 298 
DT  C4    O4     doub N N 299 
DT  C4    C5     sing N N 300 
DT  C5    C7     sing N N 301 
DT  C5    C6     doub N N 302 
DT  C7    H71    sing N N 303 
DT  C7    H72    sing N N 304 
DT  C7    H73    sing N N 305 
DT  C6    H6     sing N N 306 
G   OP3   P      sing N N 307 
G   OP3   HOP3   sing N N 308 
G   P     OP1    doub N N 309 
G   P     OP2    sing N N 310 
G   P     "O5'"  sing N N 311 
G   OP2   HOP2   sing N N 312 
G   "O5'" "C5'"  sing N N 313 
G   "C5'" "C4'"  sing N N 314 
G   "C5'" "H5'"  sing N N 315 
G   "C5'" "H5''" sing N N 316 
G   "C4'" "O4'"  sing N N 317 
G   "C4'" "C3'"  sing N N 318 
G   "C4'" "H4'"  sing N N 319 
G   "O4'" "C1'"  sing N N 320 
G   "C3'" "O3'"  sing N N 321 
G   "C3'" "C2'"  sing N N 322 
G   "C3'" "H3'"  sing N N 323 
G   "O3'" "HO3'" sing N N 324 
G   "C2'" "O2'"  sing N N 325 
G   "C2'" "C1'"  sing N N 326 
G   "C2'" "H2'"  sing N N 327 
G   "O2'" "HO2'" sing N N 328 
G   "C1'" N9     sing N N 329 
G   "C1'" "H1'"  sing N N 330 
G   N9    C8     sing Y N 331 
G   N9    C4     sing Y N 332 
G   C8    N7     doub Y N 333 
G   C8    H8     sing N N 334 
G   N7    C5     sing Y N 335 
G   C5    C6     sing N N 336 
G   C5    C4     doub Y N 337 
G   C6    O6     doub N N 338 
G   C6    N1     sing N N 339 
G   N1    C2     sing N N 340 
G   N1    H1     sing N N 341 
G   C2    N2     sing N N 342 
G   C2    N3     doub N N 343 
G   N2    H21    sing N N 344 
G   N2    H22    sing N N 345 
G   N3    C4     sing N N 346 
GLN N     CA     sing N N 347 
GLN N     H      sing N N 348 
GLN N     H2     sing N N 349 
GLN CA    C      sing N N 350 
GLN CA    CB     sing N N 351 
GLN CA    HA     sing N N 352 
GLN C     O      doub N N 353 
GLN C     OXT    sing N N 354 
GLN CB    CG     sing N N 355 
GLN CB    HB2    sing N N 356 
GLN CB    HB3    sing N N 357 
GLN CG    CD     sing N N 358 
GLN CG    HG2    sing N N 359 
GLN CG    HG3    sing N N 360 
GLN CD    OE1    doub N N 361 
GLN CD    NE2    sing N N 362 
GLN NE2   HE21   sing N N 363 
GLN NE2   HE22   sing N N 364 
GLN OXT   HXT    sing N N 365 
GLU N     CA     sing N N 366 
GLU N     H      sing N N 367 
GLU N     H2     sing N N 368 
GLU CA    C      sing N N 369 
GLU CA    CB     sing N N 370 
GLU CA    HA     sing N N 371 
GLU C     O      doub N N 372 
GLU C     OXT    sing N N 373 
GLU CB    CG     sing N N 374 
GLU CB    HB2    sing N N 375 
GLU CB    HB3    sing N N 376 
GLU CG    CD     sing N N 377 
GLU CG    HG2    sing N N 378 
GLU CG    HG3    sing N N 379 
GLU CD    OE1    doub N N 380 
GLU CD    OE2    sing N N 381 
GLU OE2   HE2    sing N N 382 
GLU OXT   HXT    sing N N 383 
GLY N     CA     sing N N 384 
GLY N     H      sing N N 385 
GLY N     H2     sing N N 386 
GLY CA    C      sing N N 387 
GLY CA    HA2    sing N N 388 
GLY CA    HA3    sing N N 389 
GLY C     O      doub N N 390 
GLY C     OXT    sing N N 391 
GLY OXT   HXT    sing N N 392 
HIS N     CA     sing N N 393 
HIS N     H      sing N N 394 
HIS N     H2     sing N N 395 
HIS CA    C      sing N N 396 
HIS CA    CB     sing N N 397 
HIS CA    HA     sing N N 398 
HIS C     O      doub N N 399 
HIS C     OXT    sing N N 400 
HIS CB    CG     sing N N 401 
HIS CB    HB2    sing N N 402 
HIS CB    HB3    sing N N 403 
HIS CG    ND1    sing Y N 404 
HIS CG    CD2    doub Y N 405 
HIS ND1   CE1    doub Y N 406 
HIS ND1   HD1    sing N N 407 
HIS CD2   NE2    sing Y N 408 
HIS CD2   HD2    sing N N 409 
HIS CE1   NE2    sing Y N 410 
HIS CE1   HE1    sing N N 411 
HIS NE2   HE2    sing N N 412 
HIS OXT   HXT    sing N N 413 
ILE N     CA     sing N N 414 
ILE N     H      sing N N 415 
ILE N     H2     sing N N 416 
ILE CA    C      sing N N 417 
ILE CA    CB     sing N N 418 
ILE CA    HA     sing N N 419 
ILE C     O      doub N N 420 
ILE C     OXT    sing N N 421 
ILE CB    CG1    sing N N 422 
ILE CB    CG2    sing N N 423 
ILE CB    HB     sing N N 424 
ILE CG1   CD1    sing N N 425 
ILE CG1   HG12   sing N N 426 
ILE CG1   HG13   sing N N 427 
ILE CG2   HG21   sing N N 428 
ILE CG2   HG22   sing N N 429 
ILE CG2   HG23   sing N N 430 
ILE CD1   HD11   sing N N 431 
ILE CD1   HD12   sing N N 432 
ILE CD1   HD13   sing N N 433 
ILE OXT   HXT    sing N N 434 
LEU N     CA     sing N N 435 
LEU N     H      sing N N 436 
LEU N     H2     sing N N 437 
LEU CA    C      sing N N 438 
LEU CA    CB     sing N N 439 
LEU CA    HA     sing N N 440 
LEU C     O      doub N N 441 
LEU C     OXT    sing N N 442 
LEU CB    CG     sing N N 443 
LEU CB    HB2    sing N N 444 
LEU CB    HB3    sing N N 445 
LEU CG    CD1    sing N N 446 
LEU CG    CD2    sing N N 447 
LEU CG    HG     sing N N 448 
LEU CD1   HD11   sing N N 449 
LEU CD1   HD12   sing N N 450 
LEU CD1   HD13   sing N N 451 
LEU CD2   HD21   sing N N 452 
LEU CD2   HD22   sing N N 453 
LEU CD2   HD23   sing N N 454 
LEU OXT   HXT    sing N N 455 
LYS N     CA     sing N N 456 
LYS N     H      sing N N 457 
LYS N     H2     sing N N 458 
LYS CA    C      sing N N 459 
LYS CA    CB     sing N N 460 
LYS CA    HA     sing N N 461 
LYS C     O      doub N N 462 
LYS C     OXT    sing N N 463 
LYS CB    CG     sing N N 464 
LYS CB    HB2    sing N N 465 
LYS CB    HB3    sing N N 466 
LYS CG    CD     sing N N 467 
LYS CG    HG2    sing N N 468 
LYS CG    HG3    sing N N 469 
LYS CD    CE     sing N N 470 
LYS CD    HD2    sing N N 471 
LYS CD    HD3    sing N N 472 
LYS CE    NZ     sing N N 473 
LYS CE    HE2    sing N N 474 
LYS CE    HE3    sing N N 475 
LYS NZ    HZ1    sing N N 476 
LYS NZ    HZ2    sing N N 477 
LYS NZ    HZ3    sing N N 478 
LYS OXT   HXT    sing N N 479 
MET N     CA     sing N N 480 
MET N     H      sing N N 481 
MET N     H2     sing N N 482 
MET CA    C      sing N N 483 
MET CA    CB     sing N N 484 
MET CA    HA     sing N N 485 
MET C     O      doub N N 486 
MET C     OXT    sing N N 487 
MET CB    CG     sing N N 488 
MET CB    HB2    sing N N 489 
MET CB    HB3    sing N N 490 
MET CG    SD     sing N N 491 
MET CG    HG2    sing N N 492 
MET CG    HG3    sing N N 493 
MET SD    CE     sing N N 494 
MET CE    HE1    sing N N 495 
MET CE    HE2    sing N N 496 
MET CE    HE3    sing N N 497 
MET OXT   HXT    sing N N 498 
PHE N     CA     sing N N 499 
PHE N     H      sing N N 500 
PHE N     H2     sing N N 501 
PHE CA    C      sing N N 502 
PHE CA    CB     sing N N 503 
PHE CA    HA     sing N N 504 
PHE C     O      doub N N 505 
PHE C     OXT    sing N N 506 
PHE CB    CG     sing N N 507 
PHE CB    HB2    sing N N 508 
PHE CB    HB3    sing N N 509 
PHE CG    CD1    doub Y N 510 
PHE CG    CD2    sing Y N 511 
PHE CD1   CE1    sing Y N 512 
PHE CD1   HD1    sing N N 513 
PHE CD2   CE2    doub Y N 514 
PHE CD2   HD2    sing N N 515 
PHE CE1   CZ     doub Y N 516 
PHE CE1   HE1    sing N N 517 
PHE CE2   CZ     sing Y N 518 
PHE CE2   HE2    sing N N 519 
PHE CZ    HZ     sing N N 520 
PHE OXT   HXT    sing N N 521 
PRO N     CA     sing N N 522 
PRO N     CD     sing N N 523 
PRO N     H      sing N N 524 
PRO CA    C      sing N N 525 
PRO CA    CB     sing N N 526 
PRO CA    HA     sing N N 527 
PRO C     O      doub N N 528 
PRO C     OXT    sing N N 529 
PRO CB    CG     sing N N 530 
PRO CB    HB2    sing N N 531 
PRO CB    HB3    sing N N 532 
PRO CG    CD     sing N N 533 
PRO CG    HG2    sing N N 534 
PRO CG    HG3    sing N N 535 
PRO CD    HD2    sing N N 536 
PRO CD    HD3    sing N N 537 
PRO OXT   HXT    sing N N 538 
SER N     CA     sing N N 539 
SER N     H      sing N N 540 
SER N     H2     sing N N 541 
SER CA    C      sing N N 542 
SER CA    CB     sing N N 543 
SER CA    HA     sing N N 544 
SER C     O      doub N N 545 
SER C     OXT    sing N N 546 
SER CB    OG     sing N N 547 
SER CB    HB2    sing N N 548 
SER CB    HB3    sing N N 549 
SER OG    HG     sing N N 550 
SER OXT   HXT    sing N N 551 
THR N     CA     sing N N 552 
THR N     H      sing N N 553 
THR N     H2     sing N N 554 
THR CA    C      sing N N 555 
THR CA    CB     sing N N 556 
THR CA    HA     sing N N 557 
THR C     O      doub N N 558 
THR C     OXT    sing N N 559 
THR CB    OG1    sing N N 560 
THR CB    CG2    sing N N 561 
THR CB    HB     sing N N 562 
THR OG1   HG1    sing N N 563 
THR CG2   HG21   sing N N 564 
THR CG2   HG22   sing N N 565 
THR CG2   HG23   sing N N 566 
THR OXT   HXT    sing N N 567 
TRP N     CA     sing N N 568 
TRP N     H      sing N N 569 
TRP N     H2     sing N N 570 
TRP CA    C      sing N N 571 
TRP CA    CB     sing N N 572 
TRP CA    HA     sing N N 573 
TRP C     O      doub N N 574 
TRP C     OXT    sing N N 575 
TRP CB    CG     sing N N 576 
TRP CB    HB2    sing N N 577 
TRP CB    HB3    sing N N 578 
TRP CG    CD1    doub Y N 579 
TRP CG    CD2    sing Y N 580 
TRP CD1   NE1    sing Y N 581 
TRP CD1   HD1    sing N N 582 
TRP CD2   CE2    doub Y N 583 
TRP CD2   CE3    sing Y N 584 
TRP NE1   CE2    sing Y N 585 
TRP NE1   HE1    sing N N 586 
TRP CE2   CZ2    sing Y N 587 
TRP CE3   CZ3    doub Y N 588 
TRP CE3   HE3    sing N N 589 
TRP CZ2   CH2    doub Y N 590 
TRP CZ2   HZ2    sing N N 591 
TRP CZ3   CH2    sing Y N 592 
TRP CZ3   HZ3    sing N N 593 
TRP CH2   HH2    sing N N 594 
TRP OXT   HXT    sing N N 595 
TYR N     CA     sing N N 596 
TYR N     H      sing N N 597 
TYR N     H2     sing N N 598 
TYR CA    C      sing N N 599 
TYR CA    CB     sing N N 600 
TYR CA    HA     sing N N 601 
TYR C     O      doub N N 602 
TYR C     OXT    sing N N 603 
TYR CB    CG     sing N N 604 
TYR CB    HB2    sing N N 605 
TYR CB    HB3    sing N N 606 
TYR CG    CD1    doub Y N 607 
TYR CG    CD2    sing Y N 608 
TYR CD1   CE1    sing Y N 609 
TYR CD1   HD1    sing N N 610 
TYR CD2   CE2    doub Y N 611 
TYR CD2   HD2    sing N N 612 
TYR CE1   CZ     doub Y N 613 
TYR CE1   HE1    sing N N 614 
TYR CE2   CZ     sing Y N 615 
TYR CE2   HE2    sing N N 616 
TYR CZ    OH     sing N N 617 
TYR OH    HH     sing N N 618 
TYR OXT   HXT    sing N N 619 
U   OP3   P      sing N N 620 
U   OP3   HOP3   sing N N 621 
U   P     OP1    doub N N 622 
U   P     OP2    sing N N 623 
U   P     "O5'"  sing N N 624 
U   OP2   HOP2   sing N N 625 
U   "O5'" "C5'"  sing N N 626 
U   "C5'" "C4'"  sing N N 627 
U   "C5'" "H5'"  sing N N 628 
U   "C5'" "H5''" sing N N 629 
U   "C4'" "O4'"  sing N N 630 
U   "C4'" "C3'"  sing N N 631 
U   "C4'" "H4'"  sing N N 632 
U   "O4'" "C1'"  sing N N 633 
U   "C3'" "O3'"  sing N N 634 
U   "C3'" "C2'"  sing N N 635 
U   "C3'" "H3'"  sing N N 636 
U   "O3'" "HO3'" sing N N 637 
U   "C2'" "O2'"  sing N N 638 
U   "C2'" "C1'"  sing N N 639 
U   "C2'" "H2'"  sing N N 640 
U   "O2'" "HO2'" sing N N 641 
U   "C1'" N1     sing N N 642 
U   "C1'" "H1'"  sing N N 643 
U   N1    C2     sing N N 644 
U   N1    C6     sing N N 645 
U   C2    O2     doub N N 646 
U   C2    N3     sing N N 647 
U   N3    C4     sing N N 648 
U   N3    H3     sing N N 649 
U   C4    O4     doub N N 650 
U   C4    C5     sing N N 651 
U   C5    C6     doub N N 652 
U   C5    H5     sing N N 653 
U   C6    H6     sing N N 654 
VAL N     CA     sing N N 655 
VAL N     H      sing N N 656 
VAL N     H2     sing N N 657 
VAL CA    C      sing N N 658 
VAL CA    CB     sing N N 659 
VAL CA    HA     sing N N 660 
VAL C     O      doub N N 661 
VAL C     OXT    sing N N 662 
VAL CB    CG1    sing N N 663 
VAL CB    CG2    sing N N 664 
VAL CB    HB     sing N N 665 
VAL CG1   HG11   sing N N 666 
VAL CG1   HG12   sing N N 667 
VAL CG1   HG13   sing N N 668 
VAL CG2   HG21   sing N N 669 
VAL CG2   HG22   sing N N 670 
VAL CG2   HG23   sing N N 671 
VAL OXT   HXT    sing N N 672 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-01-12 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MTY 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-03-05 
_em_admin.title              'Structure of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.13 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2056631 
_em_entity_assembly_naturalsource.organism             'Thermoproteota archaeon' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               1.09 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         45.4 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     14257 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   10065225 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?               ?   
'IMAGE ACQUISITION'             ? 2  ? ? 1 EPU             ?   
MASKING                         ? 3  ? ? ? ?               ?   
'CTF CORRECTION'                ? 4  1 ? ? ?               ?   
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ?   
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ?   
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' ?   
'MODEL FITTING'                 ? 8  ? 1 ? Coot            ?   
OTHER                           ? 9  ? ? ? ?               ?   
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?               ?   
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?               ?   
CLASSIFICATION                  ? 12 1 ? ? ?               ?   
RECONSTRUCTION                  ? 13 1 ? ? RELION          5.0 
'MODEL REFINEMENT'              ? 14 ? 1 ? Coot            ?   
'MODEL REFINEMENT'              ? 15 ? 1 ? ISOLDE          ?   
'MODEL REFINEMENT'              ? 16 ? 1 ? PHENIX          ?   
'VOLUME SELECTION'              ? 17 1 1 1 ?               ?   
'SERIES ALIGNMENT'              ? 18 1 1 1 ?               ?   
'MOLECULAR REPLACEMENT'         ? 19 1 1 1 ?               ?   
'LATTICE DISTORTION CORRECTION' ? 20 1 1 1 ?               ?   
'SYMMETRY DETERMINATION'        ? 21 1 1 1 ?               ?   
'CRYSTALLOGRAPHY MERGING'       ? 22 1 1 1 ?               ?   
# 
_em_specimen.concentration           1 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9MTY 'double helix'        
9MTY 'a-form double helix' 
9MTY 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 C A  1  1_555 C G  36 1_555 2.832  -4.834 1.359  -59.337 -9.363  164.421 1  C_A1:G36_C     C 1   ? C 36  ? ?  3 
1 C G  2  1_555 C C  35 1_555 -0.010 -0.108 -1.253 -24.318 -0.034  -4.375  2  C_G2:C35_C     C 2   ? C 35  ? 19 1 
1 C C  3  1_555 C G  34 1_555 0.149  -0.232 -0.989 12.273  15.148  -4.281  3  C_C3:G34_C     C 3   ? C 34  ? 19 1 
1 C U  6  1_555 E DA 5  1_555 0.102  -0.010 0.042  -13.105 1.400   0.562   4  C_U6:DA5_F     C 6   ? F 5   ? 20 1 
1 C G  7  1_555 E DC 4  1_555 -0.275 -0.234 0.389  1.767   -8.061  -0.841  5  C_G7:DC4_F     C 7   ? F 4   ? 19 1 
1 C C  8  1_555 E DG 3  1_555 0.147  -0.050 -0.139 -4.222  -0.010  -0.669  6  C_C8:DG3_F     C 8   ? F 3   ? 19 1 
1 C A  9  1_555 E DT 2  1_555 0.071  -0.223 0.413  -2.170  -6.224  0.048   7  C_A9:DT2_F     C 9   ? F 2   ? 20 1 
1 C A  10 1_555 E DT 1  1_555 -0.028 -0.155 0.247  -2.290  -11.148 0.133   8  C_A10:DT1_F    C 10  ? F 1   ? 20 1 
1 C G  11 1_555 D DC 34 1_555 -0.156 -0.112 0.126  -4.754  -12.043 -1.176  9  C_G11:DC-1_D   C 11  ? D -1  ? 19 1 
1 C C  12 1_555 D DG 33 1_555 0.104  -0.116 0.125  -7.510  -12.000 1.324   10 C_C12:DG-2_D   C 12  ? D -2  ? 19 1 
1 C C  13 1_555 D DG 32 1_555 0.061  -0.123 -0.089 -7.734  -0.498  -0.359  11 C_C13:DG-3_D   C 13  ? D -3  ? 19 1 
1 C C  14 1_555 D DG 31 1_555 0.145  -0.049 -0.090 19.415  5.232   3.971   12 C_C14:DG-4_D   C 14  ? D -4  ? 19 1 
1 C G  16 1_555 C C  21 1_555 0.088  -0.412 -1.715 -13.775 11.595  -10.371 13 C_G16:C21_C    C 16  ? C 21  ? 19 1 
1 C U  24 1_555 G DA 5  1_555 -0.100 0.012  0.361  -19.826 4.397   -0.037  14 C_U24:DA5_G    C 24  ? G 5   ? 20 1 
1 C U  25 1_555 G DA 4  1_555 0.020  -0.228 0.466  -0.905  -4.561  3.893   15 C_U25:DA4_G    C 25  ? G 4   ? 20 1 
1 C G  26 1_555 G DC 3  1_555 -0.148 -0.120 -0.193 -4.648  -0.353  0.927   16 C_G26:DC3_G    C 26  ? G 3   ? 19 1 
1 C C  27 1_555 G DG 2  1_555 0.041  0.054  0.061  1.787   -2.089  5.706   17 C_C27:DG2_G    C 27  ? G 2   ? 19 1 
1 C C  28 1_555 G DG 1  1_555 -0.001 -0.057 0.345  -1.841  -7.074  2.958   18 C_C28:DG1_G    C 28  ? G 1   ? 19 1 
1 C U  29 1_555 F DA 34 1_555 -0.071 0.005  -0.063 -3.533  -13.794 2.535   19 C_U29:DA-1_E   C 29  ? E -1  ? 20 1 
1 C U  30 1_555 F DA 33 1_555 0.075  -0.149 0.124  -6.717  -14.498 2.089   20 C_U30:DA-2_E   C 30  ? E -2  ? 20 1 
1 C A  31 1_555 F DT 32 1_555 0.124  -0.162 -0.121 -10.324 -2.989  0.866   21 C_A31:DT-3_E   C 31  ? E -3  ? 20 1 
1 C G  32 1_555 F DC 31 1_555 -0.077 -0.175 -0.193 18.869  8.258   3.376   22 C_G32:DC-4_E   C 32  ? E -4  ? 19 1 
1 D DA 12 1_555 G DT 15 1_555 0.096  -0.077 -0.288 3.946   -2.149  -0.668  23 D_DA-23:DT15_G D -23 ? G 15  ? 20 1 
1 D DA 13 1_555 G DT 14 1_555 0.089  -0.093 -0.337 4.821   -5.638  -4.989  24 D_DA-22:DT14_G D -22 ? G 14  ? 20 1 
1 D DA 14 1_555 G DT 13 1_555 0.139  -0.030 0.241  11.098  -11.132 -2.824  25 D_DA-21:DT13_G D -21 ? G 13  ? 20 1 
1 D DT 15 1_555 G DA 12 1_555 -0.261 -0.097 0.331  5.701   -17.308 -5.368  26 D_DT-20:DA12_G D -20 ? G 12  ? 20 1 
1 D DT 16 1_555 G DA 11 1_555 -0.231 -0.079 0.456  2.968   -16.524 -4.456  27 D_DT-19:DA11_G D -19 ? G 11  ? 20 1 
1 D DG 17 1_555 G DC 10 1_555 -0.251 -0.251 0.213  -2.782  -7.348  0.522   28 D_DG-18:DC10_G D -18 ? G 10  ? 19 1 
1 D DA 18 1_555 G DT 9  1_555 0.141  -0.159 0.239  -2.165  -11.551 7.467   29 D_DA-17:DT9_G  D -17 ? G 9   ? 20 1 
1 D DT 19 1_555 G DA 8  1_555 -0.026 -0.268 0.038  4.132   -9.893  4.611   30 D_DT-16:DA8_G  D -16 ? G 8   ? 20 1 
1 D DG 20 1_555 G DC 7  1_555 -0.216 -0.051 -0.057 -0.995  -12.448 0.103   31 D_DG-15:DC7_G  D -15 ? G 7   ? 19 1 
1 D DA 21 1_555 G DT 6  1_555 0.183  -0.045 -0.880 -5.515  -7.528  -2.145  32 D_DA-14:DT6_G  D -14 ? G 6   ? 20 1 
1 E DT 6  1_555 F DA 21 1_555 -0.111 -0.031 -0.431 -6.013  -14.104 -3.510  33 F_DT6:DA-14_E  F 6   ? E -14 ? 20 1 
1 E DC 7  1_555 F DG 20 1_555 0.207  -0.073 0.103  2.432   -13.197 0.752   34 F_DC7:DG-15_E  F 7   ? E -15 ? 19 1 
1 E DG 8  1_555 F DC 19 1_555 -0.214 -0.162 -0.180 -5.277  -13.714 1.865   35 F_DG8:DC-16_E  F 8   ? E -16 ? 19 1 
1 E DA 9  1_555 F DT 18 1_555 0.199  -0.196 0.157  0.096   -12.332 -1.695  36 F_DA9:DT-17_E  F 9   ? E -17 ? 20 1 
1 E DA 10 1_555 F DT 17 1_555 0.274  -0.116 -0.029 1.430   -8.639  5.977   37 F_DA10:DT-18_E F 10  ? E -18 ? 20 1 
1 E DA 11 1_555 F DT 16 1_555 0.171  -0.195 0.741  1.691   -14.257 -1.904  38 F_DA11:DT-19_E F 11  ? E -19 ? 20 1 
1 E DC 12 1_555 F DG 15 1_555 0.191  -0.141 0.308  -2.721  -9.033  -0.686  39 F_DC12:DG-20_E F 12  ? E -20 ? 19 1 
1 E DC 13 1_555 F DG 14 1_555 0.238  -0.164 0.153  -7.744  -9.823  -1.303  40 F_DC13:DG-21_E F 13  ? E -21 ? 19 1 
1 E DA 14 1_555 F DT 13 1_555 0.248  -0.127 0.092  2.196   -8.821  -4.465  41 F_DA14:DT-22_E F 14  ? E -22 ? 20 1 
1 E DC 15 1_555 F DG 12 1_555 0.159  -0.097 -0.146 6.398   0.604   1.517   42 F_DC15:DG-23_E F 15  ? E -23 ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 C A  1  1_555 C G  36 1_555 C G  2  1_555 C C  35 1_555 3.281  3.569  1.921 -125.014 88.763 171.277 1.744  -1.698 1.871 44.403  
62.537  177.989 1  CC_A1G2:C35G36_CC         C 1   ? C 36  ? C 2   ? C 35  ? 
1 C G  2  1_555 C C  35 1_555 C C  3  1_555 C G  34 1_555 0.271  0.084  2.803 -4.783   3.330  29.507  -0.419 -1.358 2.719 6.459   
9.276   30.064  2  CC_G2C3:G34C35_CC         C 2   ? C 35  ? C 3   ? C 34  ? 
1 C U  6  1_555 E DA 5  1_555 C G  7  1_555 E DC 4  1_555 1.278  -2.004 2.951 4.605    5.424  16.742  -8.974 -1.808 2.447 17.627  
-14.967 18.182  3  CC_U6G7:DC4DA5_FF         C 6   ? F 5   ? C 7   ? F 4   ? 
1 C G  7  1_555 E DC 4  1_555 C C  8  1_555 E DG 3  1_555 -0.073 -1.858 3.529 5.462    -0.459 34.054  -3.058 1.041  3.500 -0.777  
-9.251  34.480  4  CC_G7C8:DG3DC4_FF         C 7   ? F 4   ? C 8   ? F 3   ? 
1 C C  8  1_555 E DG 3  1_555 C A  9  1_555 E DT 2  1_555 0.702  -1.646 3.081 -2.575   8.296  28.950  -4.618 -1.801 2.455 16.142  
5.010   30.198  5  CC_C8A9:DT2DG3_FF         C 8   ? F 3   ? C 9   ? F 2   ? 
1 C A  9  1_555 E DT 2  1_555 C A  10 1_555 E DT 1  1_555 -1.051 -2.274 3.168 -1.975   2.395  28.493  -5.109 1.699  3.035 4.849   
3.997   28.658  6  CC_A9A10:DT1DT2_FF        C 9   ? F 2   ? C 10  ? F 1   ? 
1 C A  10 1_555 E DT 1  1_555 C G  11 1_555 D DC 34 1_555 -1.116 -1.745 3.209 -3.918   7.827  25.887  -5.510 1.457  2.711 16.869  
8.444   27.303  7  CC_A10G11:DC-1DT1_DF      C 10  ? F 1   ? C 11  ? D -1  ? 
1 C G  11 1_555 D DC 34 1_555 C C  12 1_555 D DG 33 1_555 0.576  -1.009 3.286 0.988    8.223  35.329  -2.744 -0.791 2.999 13.324  
-1.601  36.256  8  CC_G11C12:DG-2DC-1_DD     C 11  ? D -1  ? C 12  ? D -2  ? 
1 C C  12 1_555 D DG 33 1_555 C C  13 1_555 D DG 32 1_555 -0.591 -1.307 3.252 2.785    7.946  28.720  -4.071 1.684  2.733 15.600  
-5.468  29.904  9  CC_C12C13:DG-3DG-2_DD     C 12  ? D -2  ? C 13  ? D -3  ? 
1 C C  13 1_555 D DG 32 1_555 C C  14 1_555 D DG 31 1_555 0.358  0.323  3.025 -0.730   6.525  25.880  -0.894 -0.953 3.003 14.278  
1.596   26.686  10 CC_C13C14:DG-4DG-3_DD     C 13  ? D -3  ? C 14  ? D -4  ? 
1 C U  24 1_555 G DA 5  1_555 C U  25 1_555 G DA 4  1_555 1.262  -2.203 2.870 4.345    1.537  19.099  -7.123 -1.820 2.897 4.547   
-12.853 19.642  11 CC_U24U25:DA4DA5_GG       C 24  ? G 5   ? C 25  ? G 4   ? 
1 C U  25 1_555 G DA 4  1_555 C G  26 1_555 G DC 3  1_555 -0.329 -1.253 3.414 5.335    0.939  32.615  -2.367 1.509  3.284 1.658   
-9.418  33.050  12 CC_U25G26:DC3DA4_GG       C 25  ? G 4   ? C 26  ? G 3   ? 
1 C G  26 1_555 G DC 3  1_555 C C  27 1_555 G DG 2  1_555 0.823  -2.222 3.145 -0.609   4.514  25.432  -6.102 -1.994 2.696 10.149  
1.370   25.830  13 CC_G26C27:DG2DC3_GG       C 26  ? G 3   ? C 27  ? G 2   ? 
1 C C  27 1_555 G DG 2  1_555 C C  28 1_555 G DG 1  1_555 -0.676 -2.195 3.268 -6.210   5.767  29.993  -5.145 0.122  2.885 10.873  
11.708  31.141  14 CC_C27C28:DG1DG2_GG       C 27  ? G 2   ? C 28  ? G 1   ? 
1 C C  28 1_555 G DG 1  1_555 C U  29 1_555 F DA 34 1_555 -1.011 -1.625 3.218 -0.550   7.261  25.340  -5.350 2.083  2.677 16.132  
1.223   26.349  15 CC_C28U29:DA-1DG1_EG      C 28  ? G 1   ? C 29  ? E -1  ? 
1 C U  29 1_555 F DA 34 1_555 C U  30 1_555 F DA 33 1_555 0.599  -0.599 3.423 -0.596   4.696  35.232  -1.691 -1.071 3.308 7.716   
0.979   35.539  16 CC_U29U30:DA-2DA-1_EE     C 29  ? E -1  ? C 30  ? E -2  ? 
1 C U  30 1_555 F DA 33 1_555 C A  31 1_555 F DT 32 1_555 -0.249 -1.197 3.293 3.385    9.913  30.865  -3.778 1.005  2.746 17.987  
-6.142  32.553  17 CC_U30A31:DT-3DA-2_EE     C 30  ? E -2  ? C 31  ? E -3  ? 
1 C A  31 1_555 F DT 32 1_555 C G  32 1_555 F DC 31 1_555 0.187  0.295  2.857 0.755    9.491  26.340  -1.396 -0.227 2.796 20.015  
-1.592  27.979  18 CC_A31G32:DC-4DT-3_EE     C 31  ? E -3  ? C 32  ? E -4  ? 
1 D DA 12 1_555 G DT 15 1_555 D DA 13 1_555 G DT 14 1_555 -1.312 0.478  3.329 -1.190   -1.217 37.155  0.915  1.895  3.351 -1.909  
1.866   37.193  19 DD_DA-23DA-22:DT14DT15_GG D -23 ? G 15  ? D -22 ? G 14  ? 
1 D DA 13 1_555 G DT 14 1_555 D DA 14 1_555 G DT 13 1_555 -0.262 0.257  3.208 -4.043   -1.457 38.572  0.562  -0.090 3.206 -2.198  
6.097   38.802  20 DD_DA-22DA-21:DT13DT14_GG D -22 ? G 14  ? D -21 ? G 13  ? 
1 D DA 14 1_555 G DT 13 1_555 D DT 15 1_555 G DA 12 1_555 0.040  -0.858 3.358 -1.410   0.442  33.129  -1.580 -0.313 3.342 0.774   
2.472   33.161  21 DD_DA-21DT-20:DA12DT13_GG D -21 ? G 13  ? D -20 ? G 12  ? 
1 D DT 15 1_555 G DA 12 1_555 D DT 16 1_555 G DA 11 1_555 0.345  -0.424 3.253 -1.517   -1.745 36.348  -0.437 -0.761 3.253 -2.793  
2.428   36.419  22 DD_DT-20DT-19:DA11DA12_GG D -20 ? G 12  ? D -19 ? G 11  ? 
1 D DT 16 1_555 G DA 11 1_555 D DG 17 1_555 G DC 10 1_555 -0.511 -1.019 3.318 -2.220   4.443  32.650  -2.545 0.522  3.182 7.846   
3.920   33.015  23 DD_DT-19DG-18:DC10DA11_GG D -19 ? G 11  ? D -18 ? G 10  ? 
1 D DG 17 1_555 G DC 10 1_555 D DA 18 1_555 G DT 9  1_555 0.025  0.078  3.356 -2.499   1.077  34.110  -0.042 -0.447 3.347 1.832   
4.253   34.215  24 DD_DG-18DA-17:DT9DC10_GG  D -18 ? G 10  ? D -17 ? G 9   ? 
1 D DA 18 1_555 G DT 9  1_555 D DT 19 1_555 G DA 8  1_555 -0.151 0.129  3.257 -0.333   4.868  29.657  -0.749 0.223  3.238 9.429   
0.644   30.047  25 DD_DA-17DT-16:DA8DT9_GG   D -17 ? G 9   ? D -16 ? G 8   ? 
1 D DT 19 1_555 G DA 8  1_555 D DG 20 1_555 G DC 7  1_555 -0.675 0.856  3.369 -5.883   -0.108 42.971  1.170  0.317  3.426 -0.147  
7.987   43.353  26 DD_DT-16DG-15:DC7DA8_GG   D -16 ? G 8   ? D -15 ? G 7   ? 
1 D DG 20 1_555 G DC 7  1_555 D DA 21 1_555 G DT 6  1_555 -0.365 -0.151 3.549 5.237    2.940  37.269  -0.643 1.292  3.447 4.565   
-8.130  37.733  27 DD_DG-15DA-14:DT6DC7_GG   D -15 ? G 7   ? D -14 ? G 6   ? 
1 E DT 6  1_555 F DA 21 1_555 E DC 7  1_555 F DG 20 1_555 0.226  0.198  3.203 -4.269   3.785  34.382  -0.233 -1.012 3.156 6.348   
7.160   34.838  28 FF_DT6DC7:DG-15DA-14_EE   F 6   ? E -14 ? F 7   ? E -15 ? 
1 E DC 7  1_555 F DG 20 1_555 E DG 8  1_555 F DC 19 1_555 0.129  0.746  3.602 1.556    -0.391 38.654  1.179  0.016  3.597 -0.590  
-2.350  38.686  29 FF_DC7DG8:DC-16DG-15_EE   F 7   ? E -15 ? F 8   ? E -16 ? 
1 E DG 8  1_555 F DC 19 1_555 E DA 9  1_555 F DT 18 1_555 -0.448 0.044  3.252 -1.209   4.646  32.549  -0.714 0.585  3.241 8.234   
2.143   32.892  30 FF_DG8DA9:DT-17DC-16_EE   F 8   ? E -16 ? F 9   ? E -17 ? 
1 E DA 9  1_555 F DT 18 1_555 E DA 10 1_555 F DT 17 1_555 0.094  0.204  3.198 1.634    0.410  37.121  0.266  0.066  3.201 0.644   
-2.565  37.158  31 FF_DA9DA10:DT-18DT-17_EE  F 9   ? E -17 ? F 10  ? E -18 ? 
1 E DA 10 1_555 F DT 17 1_555 E DA 11 1_555 F DT 16 1_555 0.310  -0.846 3.272 -3.356   -0.734 34.311  -1.313 -1.043 3.245 -1.241  
5.671   34.477  32 FF_DA10DA11:DT-19DT-18_EE F 10  ? E -18 ? F 11  ? E -19 ? 
1 E DA 11 1_555 F DT 16 1_555 E DC 12 1_555 F DG 15 1_555 0.142  -0.924 3.366 2.160    -2.310 37.190  -1.127 0.075  3.417 -3.613  
-3.380  37.320  33 FF_DA11DC12:DG-20DT-19_EE F 11  ? E -19 ? F 12  ? E -20 ? 
1 E DC 12 1_555 F DG 15 1_555 E DC 13 1_555 F DG 14 1_555 -0.118 -0.786 3.238 2.266    2.231  30.693  -1.903 0.654  3.157 4.201   
-4.266  30.853  34 FF_DC12DC13:DG-21DG-20_EE F 12  ? E -20 ? F 13  ? E -21 ? 
1 E DC 13 1_555 F DG 14 1_555 E DA 14 1_555 F DT 13 1_555 -0.222 0.540  3.086 0.465    2.680  37.549  0.507  0.402  3.113 4.157   
-0.722  37.644  35 FF_DC13DA14:DT-22DG-21_EE F 13  ? E -21 ? F 14  ? E -22 ? 
1 E DA 14 1_555 F DT 13 1_555 E DC 15 1_555 F DG 12 1_555 0.990  0.652  3.487 4.848    -9.349 34.270  2.490  -0.869 3.306 -15.421 
-7.996  35.805  36 FF_DA14DC15:DG-23DT-22_EE F 14  ? E -22 ? F 15  ? E -23 ? 
# 
_pdbx_audit_support.funding_organization   'Howard Hughes Medical Institute (HHMI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9MTY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . THR A 1 6   ? 117.669 131.826 91.344  1.00 80.32 ? 6   THR A N     1 
ATOM   2    C  CA    . THR A 1 6   ? 118.428 130.578 91.243  1.00 80.32 ? 6   THR A CA    1 
ATOM   3    C  C     . THR A 1 6   ? 117.511 129.405 90.917  1.00 80.32 ? 6   THR A C     1 
ATOM   4    O  O     . THR A 1 6   ? 116.698 129.015 91.746  1.00 80.32 ? 6   THR A O     1 
ATOM   5    C  CB    . THR A 1 6   ? 119.171 130.276 92.554  1.00 80.32 ? 6   THR A CB    1 
ATOM   6    O  OG1   . THR A 1 6   ? 120.124 131.313 92.813  1.00 80.32 ? 6   THR A OG1   1 
ATOM   7    C  CG2   . THR A 1 6   ? 119.888 128.944 92.471  1.00 80.32 ? 6   THR A CG2   1 
ATOM   8    N  N     . ILE A 1 7   ? 117.663 128.831 89.724  1.00 78.37 ? 7   ILE A N     1 
ATOM   9    C  CA    . ILE A 1 7   ? 116.899 127.660 89.295  1.00 78.37 ? 7   ILE A CA    1 
ATOM   10   C  C     . ILE A 1 7   ? 117.762 126.415 89.454  1.00 78.37 ? 7   ILE A C     1 
ATOM   11   O  O     . ILE A 1 7   ? 118.928 126.404 89.047  1.00 78.37 ? 7   ILE A O     1 
ATOM   12   C  CB    . ILE A 1 7   ? 116.411 127.807 87.840  1.00 78.37 ? 7   ILE A CB    1 
ATOM   13   C  CG1   . ILE A 1 7   ? 115.149 128.682 87.735  1.00 78.37 ? 7   ILE A CG1   1 
ATOM   14   C  CG2   . ILE A 1 7   ? 116.156 126.445 87.217  1.00 78.37 ? 7   ILE A CG2   1 
ATOM   15   C  CD1   . ILE A 1 7   ? 115.243 130.069 88.294  1.00 78.37 ? 7   ILE A CD1   1 
ATOM   16   N  N     . LEU A 1 8   ? 117.190 125.364 90.033  1.00 77.35 ? 8   LEU A N     1 
ATOM   17   C  CA    . LEU A 1 8   ? 117.828 124.055 90.127  1.00 77.35 ? 8   LEU A CA    1 
ATOM   18   C  C     . LEU A 1 8   ? 116.868 123.016 89.570  1.00 77.35 ? 8   LEU A C     1 
ATOM   19   O  O     . LEU A 1 8   ? 115.676 123.055 89.887  1.00 77.35 ? 8   LEU A O     1 
ATOM   20   C  CB    . LEU A 1 8   ? 118.181 123.731 91.581  1.00 77.35 ? 8   LEU A CB    1 
ATOM   21   C  CG    . LEU A 1 8   ? 119.137 124.734 92.232  1.00 77.35 ? 8   LEU A CG    1 
ATOM   22   C  CD1   . LEU A 1 8   ? 119.306 124.447 93.709  1.00 77.35 ? 8   LEU A CD1   1 
ATOM   23   C  CD2   . LEU A 1 8   ? 120.484 124.749 91.527  1.00 77.35 ? 8   LEU A CD2   1 
ATOM   24   N  N     . ALA A 1 9   ? 117.365 122.112 88.722  1.00 74.46 ? 9   ALA A N     1 
ATOM   25   C  CA    . ALA A 1 9   ? 116.571 120.998 88.207  1.00 74.46 ? 9   ALA A CA    1 
ATOM   26   C  C     . ALA A 1 9   ? 116.987 119.702 88.892  1.00 74.46 ? 9   ALA A C     1 
ATOM   27   O  O     . ALA A 1 9   ? 118.150 119.309 88.822  1.00 74.46 ? 9   ALA A O     1 
ATOM   28   C  CB    . ALA A 1 9   ? 116.737 120.874 86.694  1.00 74.46 ? 9   ALA A CB    1 
ATOM   29   N  N     . VAL A 1 10  ? 116.035 119.019 89.519  1.00 68.15 ? 10  VAL A N     1 
ATOM   30   C  CA    . VAL A 1 10  ? 116.316 117.816 90.293  1.00 68.15 ? 10  VAL A CA    1 
ATOM   31   C  C     . VAL A 1 10  ? 115.698 116.584 89.633  1.00 68.15 ? 10  VAL A C     1 
ATOM   32   O  O     . VAL A 1 10  ? 114.504 116.561 89.318  1.00 68.15 ? 10  VAL A O     1 
ATOM   33   C  CB    . VAL A 1 10  ? 115.858 117.994 91.752  1.00 68.15 ? 10  VAL A CB    1 
ATOM   34   C  CG1   . VAL A 1 10  ? 114.431 118.418 91.812  1.00 68.15 ? 10  VAL A CG1   1 
ATOM   35   C  CG2   . VAL A 1 10  ? 116.046 116.698 92.532  1.00 68.15 ? 10  VAL A CG2   1 
ATOM   36   N  N     . ASP A 1 11  ? 116.546 115.584 89.378  1.00 72.05 ? 11  ASP A N     1 
ATOM   37   C  CA    . ASP A 1 11  ? 116.198 114.211 89.014  1.00 72.05 ? 11  ASP A CA    1 
ATOM   38   C  C     . ASP A 1 11  ? 116.128 113.402 90.302  1.00 72.05 ? 11  ASP A C     1 
ATOM   39   O  O     . ASP A 1 11  ? 117.148 112.899 90.800  1.00 72.05 ? 11  ASP A O     1 
ATOM   40   C  CB    . ASP A 1 11  ? 117.215 113.646 88.034  1.00 72.05 ? 11  ASP A CB    1 
ATOM   41   C  CG    . ASP A 1 11  ? 117.056 112.152 87.798  1.00 72.05 ? 11  ASP A CG    1 
ATOM   42   O  OD1   . ASP A 1 11  ? 115.941 111.614 87.931  1.00 72.05 ? 11  ASP A OD1   1 
ATOM   43   O  OD2   . ASP A 1 11  ? 118.066 111.504 87.471  1.00 72.05 ? 11  ASP A OD2   1 
ATOM   44   N  N     . TRP A 1 12  ? 114.932 113.401 90.905  1.00 63.34 ? 12  TRP A N     1 
ATOM   45   C  CA    . TRP A 1 12  ? 114.677 112.906 92.254  1.00 63.34 ? 12  TRP A CA    1 
ATOM   46   C  C     . TRP A 1 12  ? 114.767 111.384 92.345  1.00 63.34 ? 12  TRP A C     1 
ATOM   47   O  O     . TRP A 1 12  ? 114.620 110.659 91.363  1.00 63.34 ? 12  TRP A O     1 
ATOM   48   C  CB    . TRP A 1 12  ? 113.302 113.374 92.748  1.00 63.34 ? 12  TRP A CB    1 
ATOM   49   C  CG    . TRP A 1 12  ? 112.100 112.572 92.255  1.00 63.34 ? 12  TRP A CG    1 
ATOM   50   C  CD1   . TRP A 1 12  ? 111.435 112.756 91.085  1.00 63.34 ? 12  TRP A CD1   1 
ATOM   51   C  CD2   . TRP A 1 12  ? 111.437 111.475 92.918  1.00 63.34 ? 12  TRP A CD2   1 
ATOM   52   N  NE1   . TRP A 1 12  ? 110.401 111.854 90.974  1.00 63.34 ? 12  TRP A NE1   1 
ATOM   53   C  CE2   . TRP A 1 12  ? 110.383 111.060 92.087  1.00 63.34 ? 12  TRP A CE2   1 
ATOM   54   C  CE3   . TRP A 1 12  ? 111.635 110.809 94.130  1.00 63.34 ? 12  TRP A CE3   1 
ATOM   55   C  CZ2   . TRP A 1 12  ? 109.534 110.004 92.425  1.00 63.34 ? 12  TRP A CZ2   1 
ATOM   56   C  CZ3   . TRP A 1 12  ? 110.792 109.768 94.461  1.00 63.34 ? 12  TRP A CZ3   1 
ATOM   57   C  CH2   . TRP A 1 12  ? 109.757 109.373 93.612  1.00 63.34 ? 12  TRP A CH2   1 
ATOM   58   N  N     . SER A 1 13  ? 115.003 110.915 93.568  1.00 67.76 ? 13  SER A N     1 
ATOM   59   C  CA    . SER A 1 13  ? 115.000 109.509 93.933  1.00 67.76 ? 13  SER A CA    1 
ATOM   60   C  C     . SER A 1 13  ? 114.913 109.426 95.447  1.00 67.76 ? 13  SER A C     1 
ATOM   61   O  O     . SER A 1 13  ? 115.112 110.421 96.145  1.00 67.76 ? 13  SER A O     1 
ATOM   62   C  CB    . SER A 1 13  ? 116.247 108.785 93.425  1.00 67.76 ? 13  SER A CB    1 
ATOM   63   O  OG    . SER A 1 13  ? 116.187 108.567 92.027  1.00 67.76 ? 13  SER A OG    1 
ATOM   64   N  N     . HIS A 1 14  ? 114.585 108.240 95.956  1.00 69.62 ? 14  HIS A N     1 
ATOM   65   C  CA    . HIS A 1 14  ? 114.745 108.026 97.390  1.00 69.62 ? 14  HIS A CA    1 
ATOM   66   C  C     . HIS A 1 14  ? 116.173 107.615 97.734  1.00 69.62 ? 14  HIS A C     1 
ATOM   67   O  O     . HIS A 1 14  ? 116.729 108.078 98.733  1.00 69.62 ? 14  HIS A O     1 
ATOM   68   C  CB    . HIS A 1 14  ? 113.729 107.005 97.908  1.00 69.62 ? 14  HIS A CB    1 
ATOM   69   C  CG    . HIS A 1 14  ? 112.303 107.391 97.657  1.00 69.62 ? 14  HIS A CG    1 
ATOM   70   N  ND1   . HIS A 1 14  ? 111.556 106.878 96.618  1.00 69.62 ? 14  HIS A ND1   1 
ATOM   71   C  CD2   . HIS A 1 14  ? 111.499 108.274 98.293  1.00 69.62 ? 14  HIS A CD2   1 
ATOM   72   C  CE1   . HIS A 1 14  ? 110.350 107.417 96.638  1.00 69.62 ? 14  HIS A CE1   1 
ATOM   73   N  NE2   . HIS A 1 14  ? 110.293 108.275 97.639  1.00 69.62 ? 14  HIS A NE2   1 
ATOM   74   N  N     . GLU A 1 15  ? 116.787 106.772 96.907  1.00 80.01 ? 15  GLU A N     1 
ATOM   75   C  CA    . GLU A 1 15  ? 118.168 106.348 97.100  1.00 80.01 ? 15  GLU A CA    1 
ATOM   76   C  C     . GLU A 1 15  ? 119.126 107.464 96.712  1.00 80.01 ? 15  GLU A C     1 
ATOM   77   O  O     . GLU A 1 15  ? 119.096 107.949 95.576  1.00 80.01 ? 15  GLU A O     1 
ATOM   78   C  CB    . GLU A 1 15  ? 118.469 105.099 96.281  1.00 80.01 ? 15  GLU A CB    1 
ATOM   79   C  CG    . GLU A 1 15  ? 119.848 104.536 96.580  1.00 80.01 ? 15  GLU A CG    1 
ATOM   80   C  CD    . GLU A 1 15  ? 120.197 103.327 95.744  1.00 80.01 ? 15  GLU A CD    1 
ATOM   81   O  OE1   . GLU A 1 15  ? 119.771 103.273 94.571  1.00 80.01 ? 15  GLU A OE1   1 
ATOM   82   O  OE2   . GLU A 1 15  ? 120.904 102.436 96.259  1.00 80.01 ? 15  GLU A OE2   1 
ATOM   83   N  N     . GLU A 1 16  ? 119.983 107.863 97.654  1.00 83.64 ? 16  GLU A N     1 
ATOM   84   C  CA    . GLU A 1 16  ? 120.889 108.991 97.447  1.00 83.64 ? 16  GLU A CA    1 
ATOM   85   C  C     . GLU A 1 16  ? 121.964 108.716 96.394  1.00 83.64 ? 16  GLU A C     1 
ATOM   86   O  O     . GLU A 1 16  ? 122.549 109.666 95.867  1.00 83.64 ? 16  GLU A O     1 
ATOM   87   C  CB    . GLU A 1 16  ? 121.504 109.392 98.790  1.00 83.64 ? 16  GLU A CB    1 
ATOM   88   C  CG    . GLU A 1 16  ? 122.446 108.372 99.401  1.00 83.64 ? 16  GLU A CG    1 
ATOM   89   C  CD    . GLU A 1 16  ? 122.919 108.775 100.793 1.00 83.64 ? 16  GLU A CD    1 
ATOM   90   O  OE1   . GLU A 1 16  ? 122.229 108.431 101.776 1.00 83.64 ? 16  GLU A OE1   1 
ATOM   91   O  OE2   . GLU A 1 16  ? 123.978 109.429 100.907 1.00 83.64 ? 16  GLU A OE2   1 
ATOM   92   N  N     . ARG A 1 17  ? 122.218 107.450 96.061  1.00 85.70 ? 17  ARG A N     1 
ATOM   93   C  CA    . ARG A 1 17  ? 123.077 107.121 94.927  1.00 85.70 ? 17  ARG A CA    1 
ATOM   94   C  C     . ARG A 1 17  ? 122.479 107.568 93.593  1.00 85.70 ? 17  ARG A C     1 
ATOM   95   O  O     . ARG A 1 17  ? 123.224 107.949 92.685  1.00 85.70 ? 17  ARG A O     1 
ATOM   96   C  CB    . ARG A 1 17  ? 123.351 105.607 94.902  1.00 85.70 ? 17  ARG A CB    1 
ATOM   97   C  CG    . ARG A 1 17  ? 124.130 105.077 96.110  1.00 85.70 ? 17  ARG A CG    1 
ATOM   98   C  CD    . ARG A 1 17  ? 124.716 103.654 95.919  1.00 85.70 ? 17  ARG A CD    1 
ATOM   99   N  NE    . ARG A 1 17  ? 123.722 102.589 96.024  1.00 85.70 ? 17  ARG A NE    1 
ATOM   100  C  CZ    . ARG A 1 17  ? 123.999 101.313 96.279  1.00 85.70 ? 17  ARG A CZ    1 
ATOM   101  N  NH1   . ARG A 1 17  ? 125.244 100.869 96.333  1.00 85.70 ? 17  ARG A NH1   1 
ATOM   102  N  NH2   . ARG A 1 17  ? 123.000 100.459 96.480  1.00 85.70 ? 17  ARG A NH2   1 
ATOM   103  N  N     . LYS A 1 18  ? 121.150 107.517 93.446  1.00 81.88 ? 18  LYS A N     1 
ATOM   104  C  CA    . LYS A 1 18  ? 120.494 107.909 92.196  1.00 81.88 ? 18  LYS A CA    1 
ATOM   105  C  C     . LYS A 1 18  ? 120.326 109.418 92.006  1.00 81.88 ? 18  LYS A C     1 
ATOM   106  O  O     . LYS A 1 18  ? 120.282 109.879 90.862  1.00 81.88 ? 18  LYS A O     1 
ATOM   107  C  CB    . LYS A 1 18  ? 119.118 107.251 92.083  1.00 81.88 ? 18  LYS A CB    1 
ATOM   108  C  CG    . LYS A 1 18  ? 119.111 105.818 91.632  1.00 81.88 ? 18  LYS A CG    1 
ATOM   109  C  CD    . LYS A 1 18  ? 117.683 105.346 91.339  1.00 81.88 ? 18  LYS A CD    1 
ATOM   110  C  CE    . LYS A 1 18  ? 117.675 103.920 90.823  1.00 81.88 ? 18  LYS A CE    1 
ATOM   111  N  NZ    . LYS A 1 18  ? 116.301 103.409 90.596  1.00 81.88 ? 18  LYS A NZ    1 
ATOM   112  N  N     . LEU A 1 19  ? 120.195 110.186 93.085  1.00 77.72 ? 19  LEU A N     1 
ATOM   113  C  CA    . LEU A 1 19  ? 119.812 111.598 93.008  1.00 77.72 ? 19  LEU A CA    1 
ATOM   114  C  C     . LEU A 1 19  ? 120.750 112.435 92.138  1.00 77.72 ? 19  LEU A C     1 
ATOM   115  O  O     . LEU A 1 19  ? 121.965 112.232 92.137  1.00 77.72 ? 19  LEU A O     1 
ATOM   116  C  CB    . LEU A 1 19  ? 119.744 112.181 94.418  1.00 77.72 ? 19  LEU A CB    1 
ATOM   117  C  CG    . LEU A 1 19  ? 119.298 113.634 94.512  1.00 77.72 ? 19  LEU A CG    1 
ATOM   118  C  CD1   . LEU A 1 19  ? 117.903 113.757 93.980  1.00 77.72 ? 19  LEU A CD1   1 
ATOM   119  C  CD2   . LEU A 1 19  ? 119.345 114.101 95.947  1.00 77.72 ? 19  LEU A CD2   1 
ATOM   120  N  N     . ALA A 1 20  ? 120.180 113.392 91.391  1.00 77.63 ? 20  ALA A N     1 
ATOM   121  C  CA    . ALA A 1 20  ? 121.040 114.347 90.688  1.00 77.63 ? 20  ALA A CA    1 
ATOM   122  C  C     . ALA A 1 20  ? 120.376 115.713 90.551  1.00 77.63 ? 20  ALA A C     1 
ATOM   123  O  O     . ALA A 1 20  ? 119.161 115.799 90.400  1.00 77.63 ? 20  ALA A O     1 
ATOM   124  C  CB    . ALA A 1 20  ? 121.416 113.828 89.299  1.00 77.63 ? 20  ALA A CB    1 
ATOM   125  N  N     . ILE A 1 21  ? 121.178 116.782 90.627  1.00 81.93 ? 21  ILE A N     1 
ATOM   126  C  CA    . ILE A 1 21  ? 120.701 118.156 90.464  1.00 81.93 ? 21  ILE A CA    1 
ATOM   127  C  C     . ILE A 1 21  ? 121.583 118.888 89.459  1.00 81.93 ? 21  ILE A C     1 
ATOM   128  O  O     . ILE A 1 21  ? 122.808 118.749 89.481  1.00 81.93 ? 21  ILE A O     1 
ATOM   129  C  CB    . ILE A 1 21  ? 120.676 118.926 91.799  1.00 81.93 ? 21  ILE A CB    1 
ATOM   130  C  CG1   . ILE A 1 21  ? 119.839 118.194 92.839  1.00 81.93 ? 21  ILE A CG1   1 
ATOM   131  C  CG2   . ILE A 1 21  ? 120.119 120.321 91.595  1.00 81.93 ? 21  ILE A CG2   1 
ATOM   132  C  CD1   . ILE A 1 21  ? 120.631 117.294 93.737  1.00 81.93 ? 21  ILE A CD1   1 
ATOM   133  N  N     . PHE A 1 22  ? 120.960 119.665 88.578  1.00 85.40 ? 22  PHE A N     1 
ATOM   134  C  CA    . PHE A 1 22  ? 121.649 120.434 87.552  1.00 85.40 ? 22  PHE A CA    1 
ATOM   135  C  C     . PHE A 1 22  ? 121.334 121.918 87.714  1.00 85.40 ? 22  PHE A C     1 
ATOM   136  O  O     . PHE A 1 22  ? 120.160 122.298 87.820  1.00 85.40 ? 22  PHE A O     1 
ATOM   137  C  CB    . PHE A 1 22  ? 121.214 119.913 86.183  1.00 85.40 ? 22  PHE A CB    1 
ATOM   138  C  CG    . PHE A 1 22  ? 121.937 120.513 85.018  1.00 85.40 ? 22  PHE A CG    1 
ATOM   139  C  CD1   . PHE A 1 22  ? 123.308 120.398 84.897  1.00 85.40 ? 22  PHE A CD1   1 
ATOM   140  C  CD2   . PHE A 1 22  ? 121.230 121.102 83.990  1.00 85.40 ? 22  PHE A CD2   1 
ATOM   141  C  CE1   . PHE A 1 22  ? 123.964 120.912 83.808  1.00 85.40 ? 22  PHE A CE1   1 
ATOM   142  C  CE2   . PHE A 1 22  ? 121.883 121.613 82.891  1.00 85.40 ? 22  PHE A CE2   1 
ATOM   143  C  CZ    . PHE A 1 22  ? 123.252 121.520 82.804  1.00 85.40 ? 22  PHE A CZ    1 
ATOM   144  N  N     . ASP A 1 23  ? 122.374 122.755 87.754  1.00 92.56 ? 23  ASP A N     1 
ATOM   145  C  CA    . ASP A 1 23  ? 122.180 124.200 87.858  1.00 92.56 ? 23  ASP A CA    1 
ATOM   146  C  C     . ASP A 1 23  ? 122.168 124.900 86.502  1.00 92.56 ? 23  ASP A C     1 
ATOM   147  O  O     . ASP A 1 23  ? 122.058 126.127 86.456  1.00 92.56 ? 23  ASP A O     1 
ATOM   148  C  CB    . ASP A 1 23  ? 123.213 124.835 88.817  1.00 92.56 ? 23  ASP A CB    1 
ATOM   149  C  CG    . ASP A 1 23  ? 124.624 124.937 88.242  1.00 92.56 ? 23  ASP A CG    1 
ATOM   150  O  OD1   . ASP A 1 23  ? 124.873 124.565 87.086  1.00 92.56 ? 23  ASP A OD1   1 
ATOM   151  O  OD2   . ASP A 1 23  ? 125.514 125.396 88.987  1.00 92.56 ? 23  ASP A OD2   1 
ATOM   152  N  N     . GLY A 1 24  ? 122.265 124.145 85.407  1.00 91.66 ? 24  GLY A N     1 
ATOM   153  C  CA    . GLY A 1 24  ? 122.429 124.676 84.071  1.00 91.66 ? 24  GLY A CA    1 
ATOM   154  C  C     . GLY A 1 24  ? 123.855 124.677 83.562  1.00 91.66 ? 24  GLY A C     1 
ATOM   155  O  O     . GLY A 1 24  ? 124.075 124.943 82.374  1.00 91.66 ? 24  GLY A O     1 
ATOM   156  N  N     . LYS A 1 25  ? 124.819 124.402 84.428  1.00 93.75 ? 25  LYS A N     1 
ATOM   157  C  CA    . LYS A 1 25  ? 126.237 124.366 84.087  1.00 93.75 ? 25  LYS A CA    1 
ATOM   158  C  C     . LYS A 1 25  ? 126.989 123.193 84.700  1.00 93.75 ? 25  LYS A C     1 
ATOM   159  O  O     . LYS A 1 25  ? 127.918 122.689 84.064  1.00 93.75 ? 25  LYS A O     1 
ATOM   160  C  CB    . LYS A 1 25  ? 126.925 125.678 84.502  1.00 93.75 ? 25  LYS A CB    1 
ATOM   161  C  CG    . LYS A 1 25  ? 126.443 126.910 83.736  1.00 93.75 ? 25  LYS A CG    1 
ATOM   162  C  CD    . LYS A 1 25  ? 127.123 128.188 84.215  1.00 93.75 ? 25  LYS A CD    1 
ATOM   163  C  CE    . LYS A 1 25  ? 126.690 129.395 83.373  1.00 93.75 ? 25  LYS A CE    1 
ATOM   164  N  NZ    . LYS A 1 25  ? 127.264 130.683 83.846  1.00 93.75 ? 25  LYS A NZ    1 
ATOM   165  N  N     . LYS A 1 26  ? 126.624 122.736 85.900  1.00 91.44 ? 26  LYS A N     1 
ATOM   166  C  CA    . LYS A 1 26  ? 127.278 121.618 86.566  1.00 91.44 ? 26  LYS A CA    1 
ATOM   167  C  C     . LYS A 1 26  ? 126.266 120.770 87.333  1.00 91.44 ? 26  LYS A C     1 
ATOM   168  O  O     . LYS A 1 26  ? 125.153 121.206 87.639  1.00 91.44 ? 26  LYS A O     1 
ATOM   169  C  CB    . LYS A 1 26  ? 128.398 122.130 87.479  1.00 91.44 ? 26  LYS A CB    1 
ATOM   170  C  CG    . LYS A 1 26  ? 127.926 123.051 88.587  1.00 91.44 ? 26  LYS A CG    1 
ATOM   171  C  CD    . LYS A 1 26  ? 129.089 123.502 89.454  1.00 91.44 ? 26  LYS A CD    1 
ATOM   172  C  CE    . LYS A 1 26  ? 128.648 124.527 90.489  1.00 91.44 ? 26  LYS A CE    1 
ATOM   173  N  NZ    . LYS A 1 26  ? 129.783 125.025 91.312  1.00 91.44 ? 26  LYS A NZ    1 
ATOM   174  N  N     . ILE A 1 27  ? 126.683 119.533 87.630  1.00 87.60 ? 27  ILE A N     1 
ATOM   175  C  CA    . ILE A 1 27  ? 125.861 118.507 88.274  1.00 87.60 ? 27  ILE A CA    1 
ATOM   176  C  C     . ILE A 1 27  ? 126.232 118.402 89.750  1.00 87.60 ? 27  ILE A C     1 
ATOM   177  O  O     . ILE A 1 27  ? 127.415 118.314 90.093  1.00 87.60 ? 27  ILE A O     1 
ATOM   178  C  CB    . ILE A 1 27  ? 126.061 117.151 87.576  1.00 87.60 ? 27  ILE A CB    1 
ATOM   179  C  CG1   . ILE A 1 27  ? 125.607 117.215 86.113  1.00 87.60 ? 27  ILE A CG1   1 
ATOM   180  C  CG2   . ILE A 1 27  ? 125.347 116.036 88.331  1.00 87.60 ? 27  ILE A CG2   1 
ATOM   181  C  CD1   . ILE A 1 27  ? 124.120 117.222 85.914  1.00 87.60 ? 27  ILE A CD1   1 
ATOM   182  N  N     . ARG A 1 28  ? 125.227 118.376 90.623  1.00 84.96 ? 28  ARG A N     1 
ATOM   183  C  CA    . ARG A 1 28  ? 125.409 118.164 92.053  1.00 84.96 ? 28  ARG A CA    1 
ATOM   184  C  C     . ARG A 1 28  ? 124.717 116.881 92.497  1.00 84.96 ? 28  ARG A C     1 
ATOM   185  O  O     . ARG A 1 28  ? 123.720 116.462 91.906  1.00 84.96 ? 28  ARG A O     1 
ATOM   186  C  CB    . ARG A 1 28  ? 124.862 119.344 92.859  1.00 84.96 ? 28  ARG A CB    1 
ATOM   187  C  CG    . ARG A 1 28  ? 125.503 120.658 92.492  1.00 84.96 ? 28  ARG A CG    1 
ATOM   188  C  CD    . ARG A 1 28  ? 125.398 121.652 93.612  1.00 84.96 ? 28  ARG A CD    1 
ATOM   189  N  NE    . ARG A 1 28  ? 124.058 122.193 93.792  1.00 84.96 ? 28  ARG A NE    1 
ATOM   190  C  CZ    . ARG A 1 28  ? 123.744 123.096 94.710  1.00 84.96 ? 28  ARG A CZ    1 
ATOM   191  N  NH1   . ARG A 1 28  ? 124.621 123.491 95.617  1.00 84.96 ? 28  ARG A NH1   1 
ATOM   192  N  NH2   . ARG A 1 28  ? 122.516 123.600 94.732  1.00 84.96 ? 28  ARG A NH2   1 
ATOM   193  N  N     . LYS A 1 29  ? 125.276 116.233 93.521  1.00 83.78 ? 29  LYS A N     1 
ATOM   194  C  CA    . LYS A 1 29  ? 124.724 114.979 94.018  1.00 83.78 ? 29  LYS A CA    1 
ATOM   195  C  C     . LYS A 1 29  ? 123.698 115.149 95.137  1.00 83.78 ? 29  LYS A C     1 
ATOM   196  O  O     . LYS A 1 29  ? 122.929 114.214 95.390  1.00 83.78 ? 29  LYS A O     1 
ATOM   197  C  CB    . LYS A 1 29  ? 125.850 114.063 94.511  1.00 83.78 ? 29  LYS A CB    1 
ATOM   198  C  CG    . LYS A 1 29  ? 125.560 112.575 94.406  1.00 83.78 ? 29  LYS A CG    1 
ATOM   199  C  CD    . LYS A 1 29  ? 125.513 112.123 92.955  1.00 83.78 ? 29  LYS A CD    1 
ATOM   200  C  CE    . LYS A 1 29  ? 125.068 110.665 92.837  1.00 83.78 ? 29  LYS A CE    1 
ATOM   201  N  NZ    . LYS A 1 29  ? 124.333 110.403 91.568  1.00 83.78 ? 29  LYS A NZ    1 
ATOM   202  N  N     . LYS A 1 30  ? 123.672 116.294 95.827  1.00 84.82 ? 30  LYS A N     1 
ATOM   203  C  CA    . LYS A 1 30  ? 122.795 116.477 96.982  1.00 84.82 ? 30  LYS A CA    1 
ATOM   204  C  C     . LYS A 1 30  ? 122.266 117.907 97.051  1.00 84.82 ? 30  LYS A C     1 
ATOM   205  O  O     . LYS A 1 30  ? 122.876 118.842 96.530  1.00 84.82 ? 30  LYS A O     1 
ATOM   206  C  CB    . LYS A 1 30  ? 123.503 116.083 98.292  1.00 84.82 ? 30  LYS A CB    1 
ATOM   207  C  CG    . LYS A 1 30  ? 123.780 114.577 98.376  1.00 84.82 ? 30  LYS A CG    1 
ATOM   208  C  CD    . LYS A 1 30  ? 124.328 114.120 99.709  1.00 84.82 ? 30  LYS A CD    1 
ATOM   209  C  CE    . LYS A 1 30  ? 124.530 112.607 99.701  1.00 84.82 ? 30  LYS A CE    1 
ATOM   210  N  NZ    . LYS A 1 30  ? 125.077 112.115 100.991 1.00 84.82 ? 30  LYS A NZ    1 
ATOM   211  N  N     . LEU A 1 31  ? 121.102 118.055 97.691  1.00 80.82 ? 31  LEU A N     1 
ATOM   212  C  CA    . LEU A 1 31  ? 120.309 119.274 97.777  1.00 80.82 ? 31  LEU A CA    1 
ATOM   213  C  C     . LEU A 1 31  ? 120.844 120.261 98.819  1.00 80.82 ? 31  LEU A C     1 
ATOM   214  O  O     . LEU A 1 31  ? 121.472 119.860 99.801  1.00 80.82 ? 31  LEU A O     1 
ATOM   215  C  CB    . LEU A 1 31  ? 118.866 118.907 98.114  1.00 80.82 ? 31  LEU A CB    1 
ATOM   216  C  CG    . LEU A 1 31  ? 118.108 118.232 96.967  1.00 80.82 ? 31  LEU A CG    1 
ATOM   217  C  CD1   . LEU A 1 31  ? 116.870 117.495 97.470  1.00 80.82 ? 31  LEU A CD1   1 
ATOM   218  C  CD2   . LEU A 1 31  ? 117.743 119.243 95.898  1.00 80.82 ? 31  LEU A CD2   1 
ATOM   219  N  N     . PRO A 1 32  ? 120.596 121.555 98.621  1.00 81.52 ? 32  PRO A N     1 
ATOM   220  C  CA    . PRO A 1 32  ? 120.964 122.581 99.602  1.00 81.52 ? 32  PRO A CA    1 
ATOM   221  C  C     . PRO A 1 32  ? 120.000 122.640 100.786 1.00 81.52 ? 32  PRO A C     1 
ATOM   222  O  O     . PRO A 1 32  ? 119.044 121.873 100.886 1.00 81.52 ? 32  PRO A O     1 
ATOM   223  C  CB    . PRO A 1 32  ? 120.909 123.867 98.780  1.00 81.52 ? 32  PRO A CB    1 
ATOM   224  C  CG    . PRO A 1 32  ? 119.813 123.623 97.841  1.00 81.52 ? 32  PRO A CG    1 
ATOM   225  C  CD    . PRO A 1 32  ? 119.929 122.156 97.456  1.00 81.52 ? 32  PRO A CD    1 
ATOM   226  N  N     . GLU A 1 33  ? 120.298 123.562 101.709 1.00 87.30 ? 33  GLU A N     1 
ATOM   227  C  CA    . GLU A 1 33  ? 119.317 124.032 102.685 1.00 87.30 ? 33  GLU A CA    1 
ATOM   228  C  C     . GLU A 1 33  ? 118.301 124.983 102.040 1.00 87.30 ? 33  GLU A C     1 
ATOM   229  O  O     . GLU A 1 33  ? 118.652 125.761 101.148 1.00 87.30 ? 33  GLU A O     1 
ATOM   230  C  CB    . GLU A 1 33  ? 120.023 124.722 103.848 1.00 87.30 ? 33  GLU A CB    1 
ATOM   231  C  CG    . GLU A 1 33  ? 120.929 123.824 104.681 1.00 87.30 ? 33  GLU A CG    1 
ATOM   232  C  CD    . GLU A 1 33  ? 120.188 122.688 105.355 1.00 87.30 ? 33  GLU A CD    1 
ATOM   233  O  OE1   . GLU A 1 33  ? 119.030 122.895 105.777 1.00 87.30 ? 33  GLU A OE1   1 
ATOM   234  O  OE2   . GLU A 1 33  ? 120.765 121.582 105.463 1.00 87.30 ? 33  GLU A OE2   1 
ATOM   235  N  N     . PRO A 1 34  ? 117.039 124.942 102.474 1.00 83.04 ? 34  PRO A N     1 
ATOM   236  C  CA    . PRO A 1 34  ? 115.985 125.765 101.857 1.00 83.04 ? 34  PRO A CA    1 
ATOM   237  C  C     . PRO A 1 34  ? 116.216 127.275 101.917 1.00 83.04 ? 34  PRO A C     1 
ATOM   238  O  O     . PRO A 1 34  ? 116.613 127.820 102.946 1.00 83.04 ? 34  PRO A O     1 
ATOM   239  C  CB    . PRO A 1 34  ? 114.737 125.376 102.657 1.00 83.04 ? 34  PRO A CB    1 
ATOM   240  C  CG    . PRO A 1 34  ? 115.020 124.023 103.158 1.00 83.04 ? 34  PRO A CG    1 
ATOM   241  C  CD    . PRO A 1 34  ? 116.484 124.014 103.469 1.00 83.04 ? 34  PRO A CD    1 
ATOM   242  N  N     . SER A 1 35  ? 115.929 127.957 100.802 1.00 83.63 ? 35  SER A N     1 
ATOM   243  C  CA    . SER A 1 35  ? 115.907 129.418 100.772 1.00 83.63 ? 35  SER A CA    1 
ATOM   244  C  C     . SER A 1 35  ? 115.030 129.911 99.623  1.00 83.63 ? 35  SER A C     1 
ATOM   245  O  O     . SER A 1 35  ? 115.058 129.343 98.531  1.00 83.63 ? 35  SER A O     1 
ATOM   246  C  CB    . SER A 1 35  ? 117.318 129.999 100.634 1.00 83.63 ? 35  SER A CB    1 
ATOM   247  O  OG    . SER A 1 35  ? 117.272 131.414 100.525 1.00 83.63 ? 35  SER A OG    1 
ATOM   248  N  N     . SER A 1 36  ? 114.279 130.993 99.874  1.00 80.35 ? 36  SER A N     1 
ATOM   249  C  CA    . SER A 1 36  ? 113.324 131.568 98.924  1.00 80.35 ? 36  SER A CA    1 
ATOM   250  C  C     . SER A 1 36  ? 113.976 132.259 97.724  1.00 80.35 ? 36  SER A C     1 
ATOM   251  O  O     . SER A 1 36  ? 113.253 132.783 96.867  1.00 80.35 ? 36  SER A O     1 
ATOM   252  C  CB    . SER A 1 36  ? 112.397 132.552 99.647  1.00 80.35 ? 36  SER A CB    1 
ATOM   253  O  OG    . SER A 1 36  ? 113.116 133.646 100.191 1.00 80.35 ? 36  SER A OG    1 
ATOM   254  N  N     . ASP A 1 37  ? 115.305 132.317 97.661  1.00 82.52 ? 37  ASP A N     1 
ATOM   255  C  CA    . ASP A 1 37  ? 116.005 132.648 96.425  1.00 82.52 ? 37  ASP A CA    1 
ATOM   256  C  C     . ASP A 1 37  ? 115.915 131.538 95.377  1.00 82.52 ? 37  ASP A C     1 
ATOM   257  O  O     . ASP A 1 37  ? 116.107 131.814 94.187  1.00 82.52 ? 37  ASP A O     1 
ATOM   258  C  CB    . ASP A 1 37  ? 117.467 132.974 96.755  1.00 82.52 ? 37  ASP A CB    1 
ATOM   259  C  CG    . ASP A 1 37  ? 118.272 133.401 95.546  1.00 82.52 ? 37  ASP A CG    1 
ATOM   260  O  OD1   . ASP A 1 37  ? 117.922 134.423 94.923  1.00 82.52 ? 37  ASP A OD1   1 
ATOM   261  O  OD2   . ASP A 1 37  ? 119.274 132.723 95.237  1.00 82.52 ? 37  ASP A OD2   1 
ATOM   262  N  N     . VAL A 1 38  ? 115.600 130.304 95.789  1.00 78.26 ? 38  VAL A N     1 
ATOM   263  C  CA    . VAL A 1 38  ? 115.654 129.121 94.931  1.00 78.26 ? 38  VAL A CA    1 
ATOM   264  C  C     . VAL A 1 38  ? 114.281 128.791 94.354  1.00 78.26 ? 38  VAL A C     1 
ATOM   265  O  O     . VAL A 1 38  ? 113.277 128.774 95.075  1.00 78.26 ? 38  VAL A O     1 
ATOM   266  C  CB    . VAL A 1 38  ? 116.212 127.913 95.700  1.00 78.26 ? 38  VAL A CB    1 
ATOM   267  C  CG1   . VAL A 1 38  ? 116.322 126.718 94.781  1.00 78.26 ? 38  VAL A CG1   1 
ATOM   268  C  CG2   . VAL A 1 38  ? 117.562 128.251 96.289  1.00 78.26 ? 38  VAL A CG2   1 
ATOM   269  N  N     . ILE A 1 39  ? 114.245 128.535 93.048  1.00 75.79 ? 39  ILE A N     1 
ATOM   270  C  CA    . ILE A 1 39  ? 113.149 127.838 92.383  1.00 75.79 ? 39  ILE A CA    1 
ATOM   271  C  C     . ILE A 1 39  ? 113.655 126.454 91.990  1.00 75.79 ? 39  ILE A C     1 
ATOM   272  O  O     . ILE A 1 39  ? 114.676 126.333 91.306  1.00 75.79 ? 39  ILE A O     1 
ATOM   273  C  CB    . ILE A 1 39  ? 112.659 128.609 91.151  1.00 75.79 ? 39  ILE A CB    1 
ATOM   274  C  CG1   . ILE A 1 39  ? 112.123 129.980 91.554  1.00 75.79 ? 39  ILE A CG1   1 
ATOM   275  C  CG2   . ILE A 1 39  ? 111.590 127.826 90.413  1.00 75.79 ? 39  ILE A CG2   1 
ATOM   276  C  CD1   . ILE A 1 39  ? 111.773 130.859 90.371  1.00 75.79 ? 39  ILE A CD1   1 
ATOM   277  N  N     . ILE A 1 40  ? 112.952 125.414 92.429  1.00 70.35 ? 40  ILE A N     1 
ATOM   278  C  CA    . ILE A 1 40  ? 113.238 124.026 92.067  1.00 70.35 ? 40  ILE A CA    1 
ATOM   279  C  C     . ILE A 1 40  ? 112.282 123.573 90.970  1.00 70.35 ? 40  ILE A C     1 
ATOM   280  O  O     . ILE A 1 40  ? 111.109 123.961 90.963  1.00 70.35 ? 40  ILE A O     1 
ATOM   281  C  CB    . ILE A 1 40  ? 113.127 123.124 93.308  1.00 70.35 ? 40  ILE A CB    1 
ATOM   282  C  CG1   . ILE A 1 40  ? 114.125 123.573 94.369  1.00 70.35 ? 40  ILE A CG1   1 
ATOM   283  C  CG2   . ILE A 1 40  ? 113.352 121.686 92.947  1.00 70.35 ? 40  ILE A CG2   1 
ATOM   284  C  CD1   . ILE A 1 40  ? 114.159 122.684 95.568  1.00 70.35 ? 40  ILE A CD1   1 
ATOM   285  N  N     . VAL A 1 41  ? 112.791 122.804 90.003  1.00 67.70 ? 41  VAL A N     1 
ATOM   286  C  CA    . VAL A 1 41  ? 111.966 122.156 88.987  1.00 67.70 ? 41  VAL A CA    1 
ATOM   287  C  C     . VAL A 1 41  ? 112.281 120.665 88.977  1.00 67.70 ? 41  VAL A C     1 
ATOM   288  O  O     . VAL A 1 41  ? 113.443 120.269 89.100  1.00 67.70 ? 41  VAL A O     1 
ATOM   289  C  CB    . VAL A 1 41  ? 112.147 122.776 87.580  1.00 67.70 ? 41  VAL A CB    1 
ATOM   290  C  CG1   . VAL A 1 41  ? 112.030 124.287 87.638  1.00 67.70 ? 41  VAL A CG1   1 
ATOM   291  C  CG2   . VAL A 1 41  ? 113.443 122.350 86.930  1.00 67.70 ? 41  VAL A CG2   1 
ATOM   292  N  N     . ALA A 1 42  ? 111.240 119.835 88.870  1.00 63.50 ? 42  ALA A N     1 
ATOM   293  C  CA    . ALA A 1 42  ? 111.394 118.391 88.973  1.00 63.50 ? 42  ALA A CA    1 
ATOM   294  C  C     . ALA A 1 42  ? 110.358 117.694 88.109  1.00 63.50 ? 42  ALA A C     1 
ATOM   295  O  O     . ALA A 1 42  ? 109.347 118.276 87.716  1.00 63.50 ? 42  ALA A O     1 
ATOM   296  C  CB    . ALA A 1 42  ? 111.266 117.896 90.411  1.00 63.50 ? 42  ALA A CB    1 
ATOM   297  N  N     . GLU A 1 43  ? 110.661 116.441 87.770  1.00 66.55 ? 43  GLU A N     1 
ATOM   298  C  CA    . GLU A 1 43  ? 109.676 115.520 87.207  1.00 66.55 ? 43  GLU A CA    1 
ATOM   299  C  C     . GLU A 1 43  ? 109.040 114.696 88.330  1.00 66.55 ? 43  GLU A C     1 
ATOM   300  O  O     . GLU A 1 43  ? 109.415 113.552 88.589  1.00 66.55 ? 43  GLU A O     1 
ATOM   301  C  CB    . GLU A 1 43  ? 110.323 114.653 86.129  1.00 66.55 ? 43  GLU A CB    1 
ATOM   302  C  CG    . GLU A 1 43  ? 109.349 113.925 85.218  1.00 66.55 ? 43  GLU A CG    1 
ATOM   303  C  CD    . GLU A 1 43  ? 110.008 113.291 83.986  1.00 66.55 ? 43  GLU A CD    1 
ATOM   304  O  OE1   . GLU A 1 43  ? 110.949 112.490 84.145  1.00 66.55 ? 43  GLU A OE1   1 
ATOM   305  O  OE2   . GLU A 1 43  ? 109.541 113.551 82.857  1.00 66.55 ? 43  GLU A OE2   1 
ATOM   306  N  N     . ASN A 1 44  ? 108.072 115.318 89.022  1.00 60.97 ? 44  ASN A N     1 
ATOM   307  C  CA    . ASN A 1 44  ? 107.230 114.685 90.064  1.00 60.97 ? 44  ASN A CA    1 
ATOM   308  C  C     . ASN A 1 44  ? 107.906 114.350 91.408  1.00 60.97 ? 44  ASN A C     1 
ATOM   309  O  O     . ASN A 1 44  ? 107.721 113.262 91.946  1.00 60.97 ? 44  ASN A O     1 
ATOM   310  C  CB    . ASN A 1 44  ? 106.570 113.429 89.492  1.00 60.97 ? 44  ASN A CB    1 
ATOM   311  C  CG    . ASN A 1 44  ? 105.425 112.972 90.315  1.00 60.97 ? 44  ASN A CG    1 
ATOM   312  O  OD1   . ASN A 1 44  ? 104.592 113.778 90.716  1.00 60.97 ? 44  ASN A OD1   1 
ATOM   313  N  ND2   . ASN A 1 44  ? 105.377 111.673 90.606  1.00 60.97 ? 44  ASN A ND2   1 
ATOM   314  N  N     . ILE A 1 45  ? 108.680 115.284 91.956  1.00 59.29 ? 45  ILE A N     1 
ATOM   315  C  CA    . ILE A 1 45  ? 109.302 115.049 93.275  1.00 59.29 ? 45  ILE A CA    1 
ATOM   316  C  C     . ILE A 1 45  ? 108.238 114.938 94.378  1.00 59.29 ? 45  ILE A C     1 
ATOM   317  O  O     . ILE A 1 45  ? 107.304 115.760 94.427  1.00 59.29 ? 45  ILE A O     1 
ATOM   318  C  CB    . ILE A 1 45  ? 110.341 116.135 93.591  1.00 59.29 ? 45  ILE A CB    1 
ATOM   319  C  CG1   . ILE A 1 45  ? 111.167 115.707 94.806  1.00 59.29 ? 45  ILE A CG1   1 
ATOM   320  C  CG2   . ILE A 1 45  ? 109.698 117.515 93.789  1.00 59.29 ? 45  ILE A CG2   1 
ATOM   321  C  CD1   . ILE A 1 45  ? 112.420 116.492 94.997  1.00 59.29 ? 45  ILE A CD1   1 
ATOM   322  N  N     . PRO A 1 46  ? 108.316 113.940 95.267  1.00 58.76 ? 46  PRO A N     1 
ATOM   323  C  CA    . PRO A 1 46  ? 107.379 113.838 96.399  1.00 58.76 ? 46  PRO A CA    1 
ATOM   324  C  C     . PRO A 1 46  ? 107.403 115.024 97.352  1.00 58.76 ? 46  PRO A C     1 
ATOM   325  O  O     . PRO A 1 46  ? 108.404 115.725 97.500  1.00 58.76 ? 46  PRO A O     1 
ATOM   326  C  CB    . PRO A 1 46  ? 107.842 112.570 97.128  1.00 58.76 ? 46  PRO A CB    1 
ATOM   327  C  CG    . PRO A 1 46  ? 108.515 111.801 96.149  1.00 58.76 ? 46  PRO A CG    1 
ATOM   328  C  CD    . PRO A 1 46  ? 109.177 112.757 95.201  1.00 58.76 ? 46  PRO A CD    1 
ATOM   329  N  N     . GLN A 1 47  ? 106.263 115.234 98.008  1.00 62.13 ? 47  GLN A N     1 
ATOM   330  C  CA    . GLN A 1 47  ? 106.161 116.182 99.115  1.00 62.13 ? 47  GLN A CA    1 
ATOM   331  C  C     . GLN A 1 47  ? 107.064 115.821 100.301 1.00 62.13 ? 47  GLN A C     1 
ATOM   332  O  O     . GLN A 1 47  ? 107.500 116.717 101.027 1.00 62.13 ? 47  GLN A O     1 
ATOM   333  C  CB    . GLN A 1 47  ? 104.700 116.272 99.542  1.00 62.13 ? 47  GLN A CB    1 
ATOM   334  C  CG    . GLN A 1 47  ? 104.366 117.322 100.561 1.00 62.13 ? 47  GLN A CG    1 
ATOM   335  C  CD    . GLN A 1 47  ? 102.905 117.259 100.955 1.00 62.13 ? 47  GLN A CD    1 
ATOM   336  O  OE1   . GLN A 1 47  ? 102.142 118.194 100.715 1.00 62.13 ? 47  GLN A OE1   1 
ATOM   337  N  NE2   . GLN A 1 47  ? 102.495 116.130 101.516 1.00 62.13 ? 47  GLN A NE2   1 
ATOM   338  N  N     . LYS A 1 48  ? 107.355 114.528 100.511 1.00 66.61 ? 48  LYS A N     1 
ATOM   339  C  CA    . LYS A 1 48  ? 108.332 114.103 101.519 1.00 66.61 ? 48  LYS A CA    1 
ATOM   340  C  C     . LYS A 1 48  ? 109.638 114.876 101.433 1.00 66.61 ? 48  LYS A C     1 
ATOM   341  O  O     . LYS A 1 48  ? 110.220 115.244 102.457 1.00 66.61 ? 48  LYS A O     1 
ATOM   342  C  CB    . LYS A 1 48  ? 108.634 112.603 101.386 1.00 66.61 ? 48  LYS A CB    1 
ATOM   343  C  CG    . LYS A 1 48  ? 109.652 112.094 102.409 1.00 66.61 ? 48  LYS A CG    1 
ATOM   344  C  CD    . LYS A 1 48  ? 110.054 110.621 102.224 1.00 66.61 ? 48  LYS A CD    1 
ATOM   345  C  CE    . LYS A 1 48  ? 108.931 109.653 102.571 1.00 66.61 ? 48  LYS A CE    1 
ATOM   346  N  NZ    . LYS A 1 48  ? 109.374 108.219 102.526 1.00 66.61 ? 48  LYS A NZ    1 
ATOM   347  N  N     . TYR A 1 49  ? 110.141 115.087 100.224 1.00 68.11 ? 49  TYR A N     1 
ATOM   348  C  CA    . TYR A 1 49  ? 111.369 115.835 100.025 1.00 68.11 ? 49  TYR A CA    1 
ATOM   349  C  C     . TYR A 1 49  ? 111.139 117.325 99.802  1.00 68.11 ? 49  TYR A C     1 
ATOM   350  O  O     . TYR A 1 49  ? 111.952 118.137 100.253 1.00 68.11 ? 49  TYR A O     1 
ATOM   351  C  CB    . TYR A 1 49  ? 112.143 115.219 98.859  1.00 68.11 ? 49  TYR A CB    1 
ATOM   352  C  CG    . TYR A 1 49  ? 112.544 113.794 99.148  1.00 68.11 ? 49  TYR A CG    1 
ATOM   353  C  CD1   . TYR A 1 49  ? 113.416 113.502 100.180 1.00 68.11 ? 49  TYR A CD1   1 
ATOM   354  C  CD2   . TYR A 1 49  ? 112.011 112.736 98.432  1.00 68.11 ? 49  TYR A CD2   1 
ATOM   355  C  CE1   . TYR A 1 49  ? 113.781 112.204 100.464 1.00 68.11 ? 49  TYR A CE1   1 
ATOM   356  C  CE2   . TYR A 1 49  ? 112.351 111.438 98.718  1.00 68.11 ? 49  TYR A CE2   1 
ATOM   357  C  CZ    . TYR A 1 49  ? 113.241 111.173 99.734  1.00 68.11 ? 49  TYR A CZ    1 
ATOM   358  O  OH    . TYR A 1 49  ? 113.580 109.867 100.029 1.00 68.11 ? 49  TYR A OH    1 
ATOM   359  N  N     . ALA A 1 50  ? 110.049 117.714 99.151  1.00 66.01 ? 50  ALA A N     1 
ATOM   360  C  CA    . ALA A 1 50  ? 109.821 119.107 98.772  1.00 66.01 ? 50  ALA A CA    1 
ATOM   361  C  C     . ALA A 1 50  ? 109.193 119.980 99.858  1.00 66.01 ? 50  ALA A C     1 
ATOM   362  O  O     . ALA A 1 50  ? 109.310 121.208 99.782  1.00 66.01 ? 50  ALA A O     1 
ATOM   363  C  CB    . ALA A 1 50  ? 108.946 119.166 97.525  1.00 66.01 ? 50  ALA A CB    1 
ATOM   364  N  N     . ALA A 1 51  ? 108.513 119.401 100.840 1.00 71.32 ? 51  ALA A N     1 
ATOM   365  C  CA    . ALA A 1 51  ? 107.864 120.215 101.865 1.00 71.32 ? 51  ALA A CA    1 
ATOM   366  C  C     . ALA A 1 51  ? 108.801 121.156 102.621 1.00 71.32 ? 51  ALA A C     1 
ATOM   367  O  O     . ALA A 1 51  ? 108.385 122.296 102.883 1.00 71.32 ? 51  ALA A O     1 
ATOM   368  C  CB    . ALA A 1 51  ? 107.104 119.311 102.843 1.00 71.32 ? 51  ALA A CB    1 
ATOM   369  N  N     . PRO A 1 52  ? 110.018 120.767 103.025 1.00 72.79 ? 52  PRO A N     1 
ATOM   370  C  CA    . PRO A 1 52  ? 110.947 121.754 103.603 1.00 72.79 ? 52  PRO A CA    1 
ATOM   371  C  C     . PRO A 1 52  ? 111.119 123.030 102.797 1.00 72.79 ? 52  PRO A C     1 
ATOM   372  O  O     . PRO A 1 52  ? 111.268 124.107 103.384 1.00 72.79 ? 52  PRO A O     1 
ATOM   373  C  CB    . PRO A 1 52  ? 112.265 120.978 103.681 1.00 72.79 ? 52  PRO A CB    1 
ATOM   374  C  CG    . PRO A 1 52  ? 111.850 119.589 103.870 1.00 72.79 ? 52  PRO A CG    1 
ATOM   375  C  CD    . PRO A 1 52  ? 110.611 119.420 103.044 1.00 72.79 ? 52  PRO A CD    1 
ATOM   376  N  N     . PHE A 1 53  ? 111.070 122.947 101.471 1.00 72.79 ? 53  PHE A N     1 
ATOM   377  C  CA    . PHE A 1 53  ? 111.218 124.122 100.616 1.00 72.79 ? 53  PHE A CA    1 
ATOM   378  C  C     . PHE A 1 53  ? 109.947 124.971 100.548 1.00 72.79 ? 53  PHE A C     1 
ATOM   379  O  O     . PHE A 1 53  ? 110.013 126.195 100.655 1.00 72.79 ? 53  PHE A O     1 
ATOM   380  C  CB    . PHE A 1 53  ? 111.671 123.662 99.234  1.00 72.79 ? 53  PHE A CB    1 
ATOM   381  C  CG    . PHE A 1 53  ? 113.033 123.032 99.238  1.00 72.79 ? 53  PHE A CG    1 
ATOM   382  C  CD1   . PHE A 1 53  ? 114.165 123.803 99.076  1.00 72.79 ? 53  PHE A CD1   1 
ATOM   383  C  CD2   . PHE A 1 53  ? 113.186 121.677 99.469  1.00 72.79 ? 53  PHE A CD2   1 
ATOM   384  C  CE1   . PHE A 1 53  ? 115.423 123.232 99.089  1.00 72.79 ? 53  PHE A CE1   1 
ATOM   385  C  CE2   . PHE A 1 53  ? 114.447 121.101 99.495  1.00 72.79 ? 53  PHE A CE2   1 
ATOM   386  C  CZ    . PHE A 1 53  ? 115.565 121.882 99.304  1.00 72.79 ? 53  PHE A CZ    1 
ATOM   387  N  N     . ILE A 1 54  ? 108.785 124.343 100.363 1.00 70.61 ? 54  ILE A N     1 
ATOM   388  C  CA    . ILE A 1 54  ? 107.520 125.075 100.385 1.00 70.61 ? 54  ILE A CA    1 
ATOM   389  C  C     . ILE A 1 54  ? 107.317 125.761 101.730 1.00 70.61 ? 54  ILE A C     1 
ATOM   390  O  O     . ILE A 1 54  ? 106.808 126.886 101.802 1.00 70.61 ? 54  ILE A O     1 
ATOM   391  C  CB    . ILE A 1 54  ? 106.347 124.121 100.082 1.00 70.61 ? 54  ILE A CB    1 
ATOM   392  C  CG1   . ILE A 1 54  ? 106.549 123.347 98.774  1.00 70.61 ? 54  ILE A CG1   1 
ATOM   393  C  CG2   . ILE A 1 54  ? 105.038 124.906 100.006 1.00 70.61 ? 54  ILE A CG2   1 
ATOM   394  C  CD1   . ILE A 1 54  ? 106.635 124.209 97.536  1.00 70.61 ? 54  ILE A CD1   1 
ATOM   395  N  N     . GLU A 1 55  ? 107.704 125.090 102.816 1.00 75.39 ? 55  GLU A N     1 
ATOM   396  C  CA    . GLU A 1 55  ? 107.612 125.625 104.172 1.00 75.39 ? 55  GLU A CA    1 
ATOM   397  C  C     . GLU A 1 55  ? 108.479 126.856 104.416 1.00 75.39 ? 55  GLU A C     1 
ATOM   398  O  O     . GLU A 1 55  ? 108.310 127.504 105.454 1.00 75.39 ? 55  GLU A O     1 
ATOM   399  C  CB    . GLU A 1 55  ? 107.975 124.533 105.182 1.00 75.39 ? 55  GLU A CB    1 
ATOM   400  C  CG    . GLU A 1 55  ? 106.894 123.474 105.379 1.00 75.39 ? 55  GLU A CG    1 
ATOM   401  C  CD    . GLU A 1 55  ? 107.326 122.351 106.308 1.00 75.39 ? 55  GLU A CD    1 
ATOM   402  O  OE1   . GLU A 1 55  ? 108.503 122.337 106.726 1.00 75.39 ? 55  GLU A OE1   1 
ATOM   403  O  OE2   . GLU A 1 55  ? 106.486 121.481 106.621 1.00 75.39 ? 55  GLU A OE2   1 
ATOM   404  N  N     . VAL A 1 56  ? 109.408 127.186 103.517 1.00 73.78 ? 56  VAL A N     1 
ATOM   405  C  CA    . VAL A 1 56  ? 110.166 128.429 103.594 1.00 73.78 ? 56  VAL A CA    1 
ATOM   406  C  C     . VAL A 1 56  ? 109.888 129.352 102.414 1.00 73.78 ? 56  VAL A C     1 
ATOM   407  O  O     . VAL A 1 56  ? 110.561 130.368 102.261 1.00 73.78 ? 56  VAL A O     1 
ATOM   408  C  CB    . VAL A 1 56  ? 111.678 128.159 103.721 1.00 73.78 ? 56  VAL A CB    1 
ATOM   409  C  CG1   . VAL A 1 56  ? 111.944 127.083 104.772 1.00 73.78 ? 56  VAL A CG1   1 
ATOM   410  C  CG2   . VAL A 1 56  ? 112.281 127.816 102.386 1.00 73.78 ? 56  VAL A CG2   1 
ATOM   411  N  N     . GLY A 1 57  ? 108.914 129.020 101.573 1.00 73.00 ? 57  GLY A N     1 
ATOM   412  C  CA    . GLY A 1 57  ? 108.637 129.787 100.372 1.00 73.00 ? 57  GLY A CA    1 
ATOM   413  C  C     . GLY A 1 57  ? 109.553 129.526 99.198  1.00 73.00 ? 57  GLY A C     1 
ATOM   414  O  O     . GLY A 1 57  ? 109.485 130.258 98.206  1.00 73.00 ? 57  GLY A O     1 
ATOM   415  N  N     . ALA A 1 58  ? 110.400 128.506 99.274  1.00 72.27 ? 58  ALA A N     1 
ATOM   416  C  CA    . ALA A 1 58  ? 111.192 128.046 98.137  1.00 72.27 ? 58  ALA A CA    1 
ATOM   417  C  C     . ALA A 1 58  ? 110.307 127.270 97.169  1.00 72.27 ? 58  ALA A C     1 
ATOM   418  O  O     . ALA A 1 58  ? 109.939 126.122 97.437  1.00 72.27 ? 58  ALA A O     1 
ATOM   419  C  CB    . ALA A 1 58  ? 112.347 127.172 98.616  1.00 72.27 ? 58  ALA A CB    1 
ATOM   420  N  N     . LYS A 1 59  ? 109.976 127.893 96.042  1.00 66.96 ? 59  LYS A N     1 
ATOM   421  C  CA    . LYS A 1 59  ? 108.975 127.355 95.132  1.00 66.96 ? 59  LYS A CA    1 
ATOM   422  C  C     . LYS A 1 59  ? 109.441 126.040 94.520  1.00 66.96 ? 59  LYS A C     1 
ATOM   423  O  O     . LYS A 1 59  ? 110.612 125.873 94.176  1.00 66.96 ? 59  LYS A O     1 
ATOM   424  C  CB    . LYS A 1 59  ? 108.676 128.370 94.034  1.00 66.96 ? 59  LYS A CB    1 
ATOM   425  C  CG    . LYS A 1 59  ? 108.267 129.703 94.587  1.00 66.96 ? 59  LYS A CG    1 
ATOM   426  C  CD    . LYS A 1 59  ? 107.511 130.526 93.580  1.00 66.96 ? 59  LYS A CD    1 
ATOM   427  C  CE    . LYS A 1 59  ? 106.115 130.000 93.403  1.00 66.96 ? 59  LYS A CE    1 
ATOM   428  N  NZ    . LYS A 1 59  ? 105.307 130.928 92.569  1.00 66.96 ? 59  LYS A NZ    1 
ATOM   429  N  N     . VAL A 1 60  ? 108.518 125.093 94.399  1.00 62.01 ? 60  VAL A N     1 
ATOM   430  C  CA    . VAL A 1 60  ? 108.747 123.851 93.670  1.00 62.01 ? 60  VAL A CA    1 
ATOM   431  C  C     . VAL A 1 60  ? 107.774 123.772 92.503  1.00 62.01 ? 60  VAL A C     1 
ATOM   432  O  O     . VAL A 1 60  ? 106.566 123.954 92.684  1.00 62.01 ? 60  VAL A O     1 
ATOM   433  C  CB    . VAL A 1 60  ? 108.607 122.616 94.577  1.00 62.01 ? 60  VAL A CB    1 
ATOM   434  C  CG1   . VAL A 1 60  ? 108.954 121.356 93.800  1.00 62.01 ? 60  VAL A CG1   1 
ATOM   435  C  CG2   . VAL A 1 60  ? 109.503 122.750 95.790  1.00 62.01 ? 60  VAL A CG2   1 
ATOM   436  N  N     . LEU A 1 61  ? 108.307 123.578 91.303  1.00 59.98 ? 61  LEU A N     1 
ATOM   437  C  CA    . LEU A 1 61  ? 107.501 123.340 90.117  1.00 59.98 ? 61  LEU A CA    1 
ATOM   438  C  C     . LEU A 1 61  ? 107.713 121.912 89.645  1.00 59.98 ? 61  LEU A C     1 
ATOM   439  O  O     . LEU A 1 61  ? 108.846 121.436 89.581  1.00 59.98 ? 61  LEU A O     1 
ATOM   440  C  CB    . LEU A 1 61  ? 107.849 124.321 88.995  1.00 59.98 ? 61  LEU A CB    1 
ATOM   441  C  CG    . LEU A 1 61  ? 107.876 125.804 89.344  1.00 59.98 ? 61  LEU A CG    1 
ATOM   442  C  CD1   . LEU A 1 61  ? 108.182 126.594 88.089  1.00 59.98 ? 61  LEU A CD1   1 
ATOM   443  C  CD2   . LEU A 1 61  ? 106.549 126.217 89.922  1.00 59.98 ? 61  LEU A CD2   1 
ATOM   444  N  N     . ARG A 1 62  ? 106.618 121.236 89.314  1.00 58.79 ? 62  ARG A N     1 
ATOM   445  C  CA    . ARG A 1 62  ? 106.628 119.861 88.841  1.00 58.79 ? 62  ARG A CA    1 
ATOM   446  C  C     . ARG A 1 62  ? 105.928 119.751 87.492  1.00 58.79 ? 62  ARG A C     1 
ATOM   447  O  O     . ARG A 1 62  ? 105.091 120.585 87.140  1.00 58.79 ? 62  ARG A O     1 
ATOM   448  C  CB    . ARG A 1 62  ? 105.995 118.937 89.885  1.00 58.79 ? 62  ARG A CB    1 
ATOM   449  C  CG    . ARG A 1 62  ? 104.657 119.438 90.392  1.00 58.79 ? 62  ARG A CG    1 
ATOM   450  C  CD    . ARG A 1 62  ? 103.814 118.354 91.049  1.00 58.79 ? 62  ARG A CD    1 
ATOM   451  N  NE    . ARG A 1 62  ? 104.507 117.687 92.140  1.00 58.79 ? 62  ARG A NE    1 
ATOM   452  C  CZ    . ARG A 1 62  ? 103.903 116.985 93.086  1.00 58.79 ? 62  ARG A CZ    1 
ATOM   453  N  NH1   . ARG A 1 62  ? 102.589 116.980 93.205  1.00 58.79 ? 62  ARG A NH1   1 
ATOM   454  N  NH2   . ARG A 1 62  ? 104.636 116.287 93.944  1.00 58.79 ? 62  ARG A NH2   1 
ATOM   455  N  N     . CYS A 1 63  ? 106.309 118.727 86.727  1.00 63.17 ? 63  CYS A N     1 
ATOM   456  C  CA    . CYS A 1 63  ? 105.635 118.335 85.496  1.00 63.17 ? 63  CYS A CA    1 
ATOM   457  C  C     . CYS A 1 63  ? 105.408 116.822 85.473  1.00 63.17 ? 63  CYS A C     1 
ATOM   458  O  O     . CYS A 1 63  ? 106.013 116.073 86.245  1.00 63.17 ? 63  CYS A O     1 
ATOM   459  C  CB    . CYS A 1 63  ? 106.431 118.782 84.262  1.00 63.17 ? 63  CYS A CB    1 
ATOM   460  S  SG    . CYS A 1 63  ? 107.913 117.804 83.945  1.00 63.17 ? 63  CYS A SG    1 
ATOM   461  N  N     . SER A 1 64  ? 104.528 116.386 84.566  1.00 62.07 ? 64  SER A N     1 
ATOM   462  C  CA    . SER A 1 64  ? 104.148 114.981 84.435  1.00 62.07 ? 64  SER A CA    1 
ATOM   463  C  C     . SER A 1 64  ? 105.347 114.062 84.227  1.00 62.07 ? 64  SER A C     1 
ATOM   464  O  O     . SER A 1 64  ? 106.341 114.423 83.603  1.00 62.07 ? 64  SER A O     1 
ATOM   465  C  CB    . SER A 1 64  ? 103.187 114.807 83.267  1.00 62.07 ? 64  SER A CB    1 
ATOM   466  O  OG    . SER A 1 64  ? 102.868 113.443 83.093  1.00 62.07 ? 64  SER A OG    1 
ATOM   467  N  N     . THR A 1 65  ? 105.240 112.852 84.767  1.00 60.30 ? 65  THR A N     1 
ATOM   468  C  CA    . THR A 1 65  ? 106.238 111.818 84.526  1.00 60.30 ? 65  THR A CA    1 
ATOM   469  C  C     . THR A 1 65  ? 106.327 111.380 83.071  1.00 60.30 ? 65  THR A C     1 
ATOM   470  O  O     . THR A 1 65  ? 107.300 110.722 82.695  1.00 60.30 ? 65  THR A O     1 
ATOM   471  C  CB    . THR A 1 65  ? 105.913 110.598 85.369  1.00 60.30 ? 65  THR A CB    1 
ATOM   472  O  OG1   . THR A 1 65  ? 104.646 110.079 84.962  1.00 60.30 ? 65  THR A OG1   1 
ATOM   473  C  CG2   . THR A 1 65  ? 105.805 111.012 86.814  1.00 60.30 ? 65  THR A CG2   1 
ATOM   474  N  N     . ASN A 1 66  ? 105.333 111.695 82.257  1.00 63.60 ? 66  ASN A N     1 
ATOM   475  C  CA    . ASN A 1 66  ? 105.378 111.442 80.824  1.00 63.60 ? 66  ASN A CA    1 
ATOM   476  C  C     . ASN A 1 66  ? 106.016 112.549 79.981  1.00 63.60 ? 66  ASN A C     1 
ATOM   477  O  O     . ASN A 1 66  ? 106.324 112.300 78.814  1.00 63.60 ? 66  ASN A O     1 
ATOM   478  C  CB    . ASN A 1 66  ? 103.962 111.146 80.331  1.00 63.60 ? 66  ASN A CB    1 
ATOM   479  C  CG    . ASN A 1 66  ? 103.462 109.801 80.814  1.00 63.60 ? 66  ASN A CG    1 
ATOM   480  O  OD1   . ASN A 1 66  ? 104.148 108.796 80.679  1.00 63.60 ? 66  ASN A OD1   1 
ATOM   481  N  ND2   . ASN A 1 66  ? 102.273 109.781 81.396  1.00 63.60 ? 66  ASN A ND2   1 
ATOM   482  N  N     . ALA A 1 67  ? 106.240 113.744 80.534  1.00 69.25 ? 67  ALA A N     1 
ATOM   483  C  CA    . ALA A 1 67  ? 106.672 114.889 79.729  1.00 69.25 ? 67  ALA A CA    1 
ATOM   484  C  C     . ALA A 1 67  ? 107.986 114.638 78.982  1.00 69.25 ? 67  ALA A C     1 
ATOM   485  O  O     . ALA A 1 67  ? 108.097 114.939 77.787  1.00 69.25 ? 67  ALA A O     1 
ATOM   486  C  CB    . ALA A 1 67  ? 106.793 116.126 80.620  1.00 69.25 ? 67  ALA A CB    1 
ATOM   487  N  N     . THR A 1 68  ? 108.987 114.069 79.656  1.00 72.86 ? 68  THR A N     1 
ATOM   488  C  CA    . THR A 1 68  ? 110.240 113.749 78.973  1.00 72.86 ? 68  THR A CA    1 
ATOM   489  C  C     . THR A 1 68  ? 110.094 112.578 78.008  1.00 72.86 ? 68  THR A C     1 
ATOM   490  O  O     . THR A 1 68  ? 110.636 112.616 76.899  1.00 72.86 ? 68  THR A O     1 
ATOM   491  C  CB    . THR A 1 68  ? 111.337 113.466 79.996  1.00 72.86 ? 68  THR A CB    1 
ATOM   492  O  OG1   . THR A 1 68  ? 111.430 114.565 80.912  1.00 72.86 ? 68  THR A OG1   1 
ATOM   493  C  CG2   . THR A 1 68  ? 112.679 113.259 79.309  1.00 72.86 ? 68  THR A CG2   1 
ATOM   494  N  N     . ALA A 1 69  ? 109.360 111.539 78.393  1.00 76.86 ? 69  ALA A N     1 
ATOM   495  C  CA    . ALA A 1 69  ? 109.132 110.423 77.480  1.00 76.86 ? 69  ALA A CA    1 
ATOM   496  C  C     . ALA A 1 69  ? 108.421 110.868 76.206  1.00 76.86 ? 69  ALA A C     1 
ATOM   497  O  O     . ALA A 1 69  ? 108.693 110.344 75.121  1.00 76.86 ? 69  ALA A O     1 
ATOM   498  C  CB    . ALA A 1 69  ? 108.333 109.329 78.191  1.00 76.86 ? 69  ALA A CB    1 
ATOM   499  N  N     . ASP A 1 70  ? 107.508 111.832 76.314  1.00 81.18 ? 70  ASP A N     1 
ATOM   500  C  CA    . ASP A 1 70  ? 106.844 112.398 75.144  1.00 81.18 ? 70  ASP A CA    1 
ATOM   501  C  C     . ASP A 1 70  ? 107.671 113.437 74.392  1.00 81.18 ? 70  ASP A C     1 
ATOM   502  O  O     . ASP A 1 70  ? 107.393 113.675 73.213  1.00 81.18 ? 70  ASP A O     1 
ATOM   503  C  CB    . ASP A 1 70  ? 105.498 113.002 75.558  1.00 81.18 ? 70  ASP A CB    1 
ATOM   504  C  CG    . ASP A 1 70  ? 104.432 111.941 75.797  1.00 81.18 ? 70  ASP A CG    1 
ATOM   505  O  OD1   . ASP A 1 70  ? 104.490 110.890 75.125  1.00 81.18 ? 70  ASP A OD1   1 
ATOM   506  O  OD2   . ASP A 1 70  ? 103.545 112.149 76.655  1.00 81.18 ? 70  ASP A OD2   1 
ATOM   507  N  N     . ALA A 1 71  ? 108.652 114.081 75.027  1.00 82.41 ? 71  ALA A N     1 
ATOM   508  C  CA    . ALA A 1 71  ? 109.658 114.810 74.252  1.00 82.41 ? 71  ALA A CA    1 
ATOM   509  C  C     . ALA A 1 71  ? 110.568 113.865 73.468  1.00 82.41 ? 71  ALA A C     1 
ATOM   510  O  O     . ALA A 1 71  ? 110.958 114.167 72.336  1.00 82.41 ? 71  ALA A O     1 
ATOM   511  C  CB    . ALA A 1 71  ? 110.486 115.708 75.167  1.00 82.41 ? 71  ALA A CB    1 
ATOM   512  N  N     . ARG A 1 72  ? 110.912 112.715 74.050  1.00 86.49 ? 72  ARG A N     1 
ATOM   513  C  CA    . ARG A 1 72  ? 111.738 111.698 73.405  1.00 86.49 ? 72  ARG A CA    1 
ATOM   514  C  C     . ARG A 1 72  ? 111.054 110.983 72.240  1.00 86.49 ? 72  ARG A C     1 
ATOM   515  O  O     . ARG A 1 72  ? 111.699 110.149 71.597  1.00 86.49 ? 72  ARG A O     1 
ATOM   516  C  CB    . ARG A 1 72  ? 112.205 110.688 74.452  1.00 86.49 ? 72  ARG A CB    1 
ATOM   517  C  CG    . ARG A 1 72  ? 113.332 111.207 75.342  1.00 86.49 ? 72  ARG A CG    1 
ATOM   518  C  CD    . ARG A 1 72  ? 113.655 110.227 76.470  1.00 86.49 ? 72  ARG A CD    1 
ATOM   519  N  NE    . ARG A 1 72  ? 114.930 110.532 77.109  1.00 86.49 ? 72  ARG A NE    1 
ATOM   520  C  CZ    . ARG A 1 72  ? 115.270 110.152 78.332  1.00 86.49 ? 72  ARG A CZ    1 
ATOM   521  N  NH1   . ARG A 1 72  ? 114.386 109.630 79.163  1.00 86.49 ? 72  ARG A NH1   1 
ATOM   522  N  NH2   . ARG A 1 72  ? 116.521 110.335 78.744  1.00 86.49 ? 72  ARG A NH2   1 
ATOM   523  N  N     . LYS A 1 73  ? 109.784 111.270 71.948  1.00 86.95 ? 73  LYS A N     1 
ATOM   524  C  CA    . LYS A 1 73  ? 109.191 110.808 70.697  1.00 86.95 ? 73  LYS A CA    1 
ATOM   525  C  C     . LYS A 1 73  ? 109.713 111.581 69.487  1.00 86.95 ? 73  LYS A C     1 
ATOM   526  O  O     . LYS A 1 73  ? 109.508 111.140 68.352  1.00 86.95 ? 73  LYS A O     1 
ATOM   527  C  CB    . LYS A 1 73  ? 107.666 110.928 70.747  1.00 86.95 ? 73  LYS A CB    1 
ATOM   528  C  CG    . LYS A 1 73  ? 107.006 110.280 71.948  1.00 86.95 ? 73  LYS A CG    1 
ATOM   529  C  CD    . LYS A 1 73  ? 107.067 108.758 71.903  1.00 86.95 ? 73  LYS A CD    1 
ATOM   530  C  CE    . LYS A 1 73  ? 106.705 108.159 73.262  1.00 86.95 ? 73  LYS A CE    1 
ATOM   531  N  NZ    . LYS A 1 73  ? 105.297 108.419 73.644  1.00 86.95 ? 73  LYS A NZ    1 
ATOM   532  N  N     . ASN A 1 74  ? 110.355 112.727 69.699  1.00 93.38 ? 74  ASN A N     1 
ATOM   533  C  CA    . ASN A 1 74  ? 110.803 113.585 68.599  1.00 93.38 ? 74  ASN A CA    1 
ATOM   534  C  C     . ASN A 1 74  ? 112.257 113.337 68.195  1.00 93.38 ? 74  ASN A C     1 
ATOM   535  O  O     . ASN A 1 74  ? 113.161 113.299 69.031  1.00 93.38 ? 74  ASN A O     1 
ATOM   536  C  CB    . ASN A 1 74  ? 110.625 115.056 68.974  1.00 93.38 ? 74  ASN A CB    1 
ATOM   537  C  CG    . ASN A 1 74  ? 109.217 115.371 69.422  1.00 93.38 ? 74  ASN A CG    1 
ATOM   538  O  OD1   . ASN A 1 74  ? 108.299 115.447 68.610  1.00 93.38 ? 74  ASN A OD1   1 
ATOM   539  N  ND2   . ASN A 1 74  ? 109.039 115.561 70.723  1.00 93.38 ? 74  ASN A ND2   1 
ATOM   540  N  N     . ASN A 1 86  ? 123.463 107.247 81.008  1.00 95.80 ? 86  ASN A N     1 
ATOM   541  C  CA    . ASN A 1 86  ? 123.073 107.240 82.417  1.00 95.80 ? 86  ASN A CA    1 
ATOM   542  C  C     . ASN A 1 86  ? 121.748 107.959 82.670  1.00 95.80 ? 86  ASN A C     1 
ATOM   543  O  O     . ASN A 1 86  ? 121.177 108.585 81.777  1.00 95.80 ? 86  ASN A O     1 
ATOM   544  C  CB    . ASN A 1 86  ? 124.193 107.820 83.297  1.00 95.80 ? 86  ASN A CB    1 
ATOM   545  C  CG    . ASN A 1 86  ? 124.484 109.291 83.023  1.00 95.80 ? 86  ASN A CG    1 
ATOM   546  O  OD1   . ASN A 1 86  ? 123.589 110.091 82.758  1.00 95.80 ? 86  ASN A OD1   1 
ATOM   547  N  ND2   . ASN A 1 86  ? 125.760 109.650 83.103  1.00 95.80 ? 86  ASN A ND2   1 
ATOM   548  N  N     . ASP A 1 87  ? 121.275 107.851 83.912  1.00 93.17 ? 87  ASP A N     1 
ATOM   549  C  CA    . ASP A 1 87  ? 120.114 108.616 84.361  1.00 93.17 ? 87  ASP A CA    1 
ATOM   550  C  C     . ASP A 1 87  ? 120.412 110.107 84.494  1.00 93.17 ? 87  ASP A C     1 
ATOM   551  O  O     . ASP A 1 87  ? 119.546 110.940 84.213  1.00 93.17 ? 87  ASP A O     1 
ATOM   552  C  CB    . ASP A 1 87  ? 119.627 108.050 85.694  1.00 93.17 ? 87  ASP A CB    1 
ATOM   553  C  CG    . ASP A 1 87  ? 118.329 108.679 86.167  1.00 93.17 ? 87  ASP A CG    1 
ATOM   554  O  OD1   . ASP A 1 87  ? 117.574 109.219 85.331  1.00 93.17 ? 87  ASP A OD1   1 
ATOM   555  O  OD2   . ASP A 1 87  ? 118.061 108.620 87.384  1.00 93.17 ? 87  ASP A OD2   1 
ATOM   556  N  N     . GLU A 1 88  ? 121.628 110.461 84.918  1.00 92.48 ? 88  GLU A N     1 
ATOM   557  C  CA    . GLU A 1 88  ? 121.942 111.843 85.292  1.00 92.48 ? 88  GLU A CA    1 
ATOM   558  C  C     . GLU A 1 88  ? 121.741 112.854 84.156  1.00 92.48 ? 88  GLU A C     1 
ATOM   559  O  O     . GLU A 1 88  ? 121.503 114.034 84.425  1.00 92.48 ? 88  GLU A O     1 
ATOM   560  C  CB    . GLU A 1 88  ? 123.371 111.909 85.832  1.00 92.48 ? 88  GLU A CB    1 
ATOM   561  C  CG    . GLU A 1 88  ? 123.592 111.039 87.063  1.00 92.48 ? 88  GLU A CG    1 
ATOM   562  C  CD    . GLU A 1 88  ? 124.990 111.170 87.653  1.00 92.48 ? 88  GLU A CD    1 
ATOM   563  O  OE1   . GLU A 1 88  ? 125.934 111.492 86.902  1.00 92.48 ? 88  GLU A OE1   1 
ATOM   564  O  OE2   . GLU A 1 88  ? 125.146 110.931 88.868  1.00 92.48 ? 88  GLU A OE2   1 
ATOM   565  N  N     . ASN A 1 89  ? 121.862 112.427 82.894  1.00 89.81 ? 89  ASN A N     1 
ATOM   566  C  CA    . ASN A 1 89  ? 121.462 113.264 81.757  1.00 89.81 ? 89  ASN A CA    1 
ATOM   567  C  C     . ASN A 1 89  ? 119.998 113.709 81.813  1.00 89.81 ? 89  ASN A C     1 
ATOM   568  O  O     . ASN A 1 89  ? 119.642 114.758 81.252  1.00 89.81 ? 89  ASN A O     1 
ATOM   569  C  CB    . ASN A 1 89  ? 121.721 112.516 80.445  1.00 89.81 ? 89  ASN A CB    1 
ATOM   570  C  CG    . ASN A 1 89  ? 123.168 112.628 79.974  1.00 89.81 ? 89  ASN A CG    1 
ATOM   571  O  OD1   . ASN A 1 89  ? 123.878 113.571 80.321  1.00 89.81 ? 89  ASN A OD1   1 
ATOM   572  N  ND2   . ASN A 1 89  ? 123.605 111.660 79.173  1.00 89.81 ? 89  ASN A ND2   1 
ATOM   573  N  N     . ASP A 1 90  ? 119.119 112.919 82.433  1.00 87.64 ? 90  ASP A N     1 
ATOM   574  C  CA    . ASP A 1 90  ? 117.718 113.325 82.487  1.00 87.64 ? 90  ASP A CA    1 
ATOM   575  C  C     . ASP A 1 90  ? 117.493 114.563 83.345  1.00 87.64 ? 90  ASP A C     1 
ATOM   576  O  O     . ASP A 1 90  ? 116.520 115.285 83.118  1.00 87.64 ? 90  ASP A O     1 
ATOM   577  C  CB    . ASP A 1 90  ? 116.835 112.176 82.980  1.00 87.64 ? 90  ASP A CB    1 
ATOM   578  C  CG    . ASP A 1 90  ? 116.797 110.998 82.009  1.00 87.64 ? 90  ASP A CG    1 
ATOM   579  O  OD1   . ASP A 1 90  ? 117.745 110.830 81.211  1.00 87.64 ? 90  ASP A OD1   1 
ATOM   580  O  OD2   . ASP A 1 90  ? 115.795 110.249 82.026  1.00 87.64 ? 90  ASP A OD2   1 
ATOM   581  N  N     . SER A 1 91  ? 118.354 114.837 84.327  1.00 81.11 ? 91  SER A N     1 
ATOM   582  C  CA    . SER A 1 91  ? 118.277 116.132 85.003  1.00 81.11 ? 91  SER A CA    1 
ATOM   583  C  C     . SER A 1 91  ? 118.517 117.279 84.033  1.00 81.11 ? 91  SER A C     1 
ATOM   584  O  O     . SER A 1 91  ? 117.873 118.332 84.129  1.00 81.11 ? 91  SER A O     1 
ATOM   585  C  CB    . SER A 1 91  ? 119.280 116.200 86.150  1.00 81.11 ? 91  SER A CB    1 
ATOM   586  O  OG    . SER A 1 91  ? 120.600 116.265 85.657  1.00 81.11 ? 91  SER A OG    1 
ATOM   587  N  N     . LYS A 1 92  ? 119.377 117.057 83.040  1.00 83.17 ? 92  LYS A N     1 
ATOM   588  C  CA    . LYS A 1 92  ? 119.624 118.066 82.020  1.00 83.17 ? 92  LYS A CA    1 
ATOM   589  C  C     . LYS A 1 92  ? 118.431 118.212 81.095  1.00 83.17 ? 92  LYS A C     1 
ATOM   590  O  O     . LYS A 1 92  ? 118.091 119.325 80.690  1.00 83.17 ? 92  LYS A O     1 
ATOM   591  C  CB    . LYS A 1 92  ? 120.872 117.706 81.218  1.00 83.17 ? 92  LYS A CB    1 
ATOM   592  C  CG    . LYS A 1 92  ? 122.076 117.333 82.057  1.00 83.17 ? 92  LYS A CG    1 
ATOM   593  C  CD    . LYS A 1 92  ? 123.219 116.895 81.168  1.00 83.17 ? 92  LYS A CD    1 
ATOM   594  C  CE    . LYS A 1 92  ? 124.425 116.452 81.974  1.00 83.17 ? 92  LYS A CE    1 
ATOM   595  N  NZ    . LYS A 1 92  ? 125.459 115.825 81.112  1.00 83.17 ? 92  LYS A NZ    1 
ATOM   596  N  N     . VAL A 1 93  ? 117.784 117.102 80.757  1.00 78.69 ? 93  VAL A N     1 
ATOM   597  C  CA    . VAL A 1 93  ? 116.562 117.176 79.955  1.00 78.69 ? 93  VAL A CA    1 
ATOM   598  C  C     . VAL A 1 93  ? 115.433 117.876 80.711  1.00 78.69 ? 93  VAL A C     1 
ATOM   599  O  O     . VAL A 1 93  ? 114.657 118.633 80.121  1.00 78.69 ? 93  VAL A O     1 
ATOM   600  C  CB    . VAL A 1 93  ? 116.120 115.775 79.500  1.00 78.69 ? 93  VAL A CB    1 
ATOM   601  C  CG1   . VAL A 1 93  ? 115.004 115.903 78.488  1.00 78.69 ? 93  VAL A CG1   1 
ATOM   602  C  CG2   . VAL A 1 93  ? 117.282 114.997 78.921  1.00 78.69 ? 93  VAL A CG2   1 
ATOM   603  N  N     . ILE A 1 94  ? 115.291 117.608 82.009  1.00 76.63 ? 94  ILE A N     1 
ATOM   604  C  CA    . ILE A 1 94  ? 114.314 118.329 82.827  1.00 76.63 ? 94  ILE A CA    1 
ATOM   605  C  C     . ILE A 1 94  ? 114.592 119.827 82.808  1.00 76.63 ? 94  ILE A C     1 
ATOM   606  O  O     . ILE A 1 94  ? 113.679 120.649 82.640  1.00 76.63 ? 94  ILE A O     1 
ATOM   607  C  CB    . ILE A 1 94  ? 114.323 117.783 84.266  1.00 76.63 ? 94  ILE A CB    1 
ATOM   608  C  CG1   . ILE A 1 94  ? 113.812 116.347 84.310  1.00 76.63 ? 94  ILE A CG1   1 
ATOM   609  C  CG2   . ILE A 1 94  ? 113.467 118.645 85.184  1.00 76.63 ? 94  ILE A CG2   1 
ATOM   610  C  CD1   . ILE A 1 94  ? 114.214 115.633 85.572  1.00 76.63 ? 94  ILE A CD1   1 
ATOM   611  N  N     . TRP A 1 95  ? 115.866 120.200 82.964  1.00 81.27 ? 95  TRP A N     1 
ATOM   612  C  CA    . TRP A 1 95  ? 116.264 121.605 82.896  1.00 81.27 ? 95  TRP A CA    1 
ATOM   613  C  C     . TRP A 1 95  ? 115.984 122.211 81.521  1.00 81.27 ? 95  TRP A C     1 
ATOM   614  O  O     . TRP A 1 95  ? 115.465 123.331 81.409  1.00 81.27 ? 95  TRP A O     1 
ATOM   615  C  CB    . TRP A 1 95  ? 117.748 121.709 83.258  1.00 81.27 ? 95  TRP A CB    1 
ATOM   616  C  CG    . TRP A 1 95  ? 118.277 123.101 83.450  1.00 81.27 ? 95  TRP A CG    1 
ATOM   617  C  CD1   . TRP A 1 95  ? 118.445 123.749 84.634  1.00 81.27 ? 95  TRP A CD1   1 
ATOM   618  C  CD2   . TRP A 1 95  ? 118.724 124.007 82.429  1.00 81.27 ? 95  TRP A CD2   1 
ATOM   619  N  NE1   . TRP A 1 95  ? 118.960 125.002 84.418  1.00 81.27 ? 95  TRP A NE1   1 
ATOM   620  C  CE2   . TRP A 1 95  ? 119.139 125.184 83.073  1.00 81.27 ? 95  TRP A CE2   1 
ATOM   621  C  CE3   . TRP A 1 95  ? 118.809 123.934 81.036  1.00 81.27 ? 95  TRP A CE3   1 
ATOM   622  C  CZ2   . TRP A 1 95  ? 119.622 126.285 82.376  1.00 81.27 ? 95  TRP A CZ2   1 
ATOM   623  C  CZ3   . TRP A 1 95  ? 119.288 125.023 80.344  1.00 81.27 ? 95  TRP A CZ3   1 
ATOM   624  C  CH2   . TRP A 1 95  ? 119.692 126.186 81.013  1.00 81.27 ? 95  TRP A CH2   1 
ATOM   625  N  N     . ALA A 1 96  ? 116.294 121.466 80.465  1.00 76.74 ? 96  ALA A N     1 
ATOM   626  C  CA    . ALA A 1 96  ? 116.035 121.913 79.103  1.00 76.74 ? 96  ALA A CA    1 
ATOM   627  C  C     . ALA A 1 96  ? 114.550 122.089 78.812  1.00 76.74 ? 96  ALA A C     1 
ATOM   628  O  O     . ALA A 1 96  ? 114.170 123.031 78.120  1.00 76.74 ? 96  ALA A O     1 
ATOM   629  C  CB    . ALA A 1 96  ? 116.654 120.920 78.121  1.00 76.74 ? 96  ALA A CB    1 
ATOM   630  N  N     . LEU A 1 97  ? 113.702 121.177 79.294  1.00 76.93 ? 97  LEU A N     1 
ATOM   631  C  CA    . LEU A 1 97  ? 112.252 121.322 79.138  1.00 76.93 ? 97  LEU A CA    1 
ATOM   632  C  C     . LEU A 1 97  ? 111.680 122.463 79.959  1.00 76.93 ? 97  LEU A C     1 
ATOM   633  O  O     . LEU A 1 97  ? 110.708 123.093 79.533  1.00 76.93 ? 97  LEU A O     1 
ATOM   634  C  CB    . LEU A 1 97  ? 111.533 120.022 79.486  1.00 76.93 ? 97  LEU A CB    1 
ATOM   635  C  CG    . LEU A 1 97  ? 111.210 119.102 78.306  1.00 76.93 ? 97  LEU A CG    1 
ATOM   636  C  CD1   . LEU A 1 97  ? 110.064 119.676 77.500  1.00 76.93 ? 97  LEU A CD1   1 
ATOM   637  C  CD2   . LEU A 1 97  ? 112.415 118.900 77.410  1.00 76.93 ? 97  LEU A CD2   1 
ATOM   638  N  N     . TYR A 1 98  ? 112.232 122.731 81.141  1.00 74.54 ? 98  TYR A N     1 
ATOM   639  C  CA    . TYR A 1 98  ? 111.831 123.944 81.845  1.00 74.54 ? 98  TYR A CA    1 
ATOM   640  C  C     . TYR A 1 98  ? 112.210 125.195 81.062  1.00 74.54 ? 98  TYR A C     1 
ATOM   641  O  O     . TYR A 1 98  ? 111.490 126.196 81.105  1.00 74.54 ? 98  TYR A O     1 
ATOM   642  C  CB    . TYR A 1 98  ? 112.430 123.992 83.246  1.00 74.54 ? 98  TYR A CB    1 
ATOM   643  C  CG    . TYR A 1 98  ? 112.074 125.259 84.004  1.00 74.54 ? 98  TYR A CG    1 
ATOM   644  C  CD1   . TYR A 1 98  ? 110.768 125.518 84.386  1.00 74.54 ? 98  TYR A CD1   1 
ATOM   645  C  CD2   . TYR A 1 98  ? 113.043 126.183 84.344  1.00 74.54 ? 98  TYR A CD2   1 
ATOM   646  C  CE1   . TYR A 1 98  ? 110.439 126.644 85.080  1.00 74.54 ? 98  TYR A CE1   1 
ATOM   647  C  CE2   . TYR A 1 98  ? 112.719 127.325 85.039  1.00 74.54 ? 98  TYR A CE2   1 
ATOM   648  C  CZ    . TYR A 1 98  ? 111.413 127.552 85.405  1.00 74.54 ? 98  TYR A CZ    1 
ATOM   649  O  OH    . TYR A 1 98  ? 111.078 128.700 86.090  1.00 74.54 ? 98  TYR A OH    1 
ATOM   650  N  N     . GLN A 1 99  ? 113.344 125.171 80.355  1.00 78.44 ? 99  GLN A N     1 
ATOM   651  C  CA    . GLN A 1 99  ? 113.676 126.329 79.521  1.00 78.44 ? 99  GLN A CA    1 
ATOM   652  C  C     . GLN A 1 99  ? 112.869 126.409 78.220  1.00 78.44 ? 99  GLN A C     1 
ATOM   653  O  O     . GLN A 1 99  ? 112.445 127.504 77.829  1.00 78.44 ? 99  GLN A O     1 
ATOM   654  C  CB    . GLN A 1 99  ? 115.175 126.350 79.210  1.00 78.44 ? 99  GLN A CB    1 
ATOM   655  C  CG    . GLN A 1 99  ? 116.071 126.622 80.422  1.00 78.44 ? 99  GLN A CG    1 
ATOM   656  C  CD    . GLN A 1 99  ? 115.820 127.982 81.066  1.00 78.44 ? 99  GLN A CD    1 
ATOM   657  O  OE1   . GLN A 1 99  ? 115.152 128.840 80.499  1.00 78.44 ? 99  GLN A OE1   1 
ATOM   658  N  NE2   . GLN A 1 99  ? 116.347 128.171 82.266  1.00 78.44 ? 99  GLN A NE2   1 
ATOM   659  N  N     . THR A 1 100 ? 112.647 125.288 77.530  1.00 79.34 ? 100 THR A N     1 
ATOM   660  C  CA    . THR A 1 100 ? 112.002 125.306 76.219  1.00 79.34 ? 100 THR A CA    1 
ATOM   661  C  C     . THR A 1 100 ? 110.483 125.264 76.304  1.00 79.34 ? 100 THR A C     1 
ATOM   662  O  O     . THR A 1 100 ? 109.802 125.908 75.498  1.00 79.34 ? 100 THR A O     1 
ATOM   663  C  CB    . THR A 1 100 ? 112.485 124.139 75.341  1.00 79.34 ? 100 THR A CB    1 
ATOM   664  O  OG1   . THR A 1 100 ? 112.318 122.888 76.022  1.00 79.34 ? 100 THR A OG1   1 
ATOM   665  C  CG2   . THR A 1 100 ? 113.948 124.311 74.978  1.00 79.34 ? 100 THR A CG2   1 
ATOM   666  N  N     . HIS A 1 101 ? 109.940 124.545 77.286  1.00 79.53 ? 101 HIS A N     1 
ATOM   667  C  CA    . HIS A 1 101 ? 108.494 124.394 77.475  1.00 79.53 ? 101 HIS A CA    1 
ATOM   668  C  C     . HIS A 1 101 ? 108.064 124.789 78.885  1.00 79.53 ? 101 HIS A C     1 
ATOM   669  O  O     . HIS A 1 101 ? 107.491 123.981 79.620  1.00 79.53 ? 101 HIS A O     1 
ATOM   670  C  CB    . HIS A 1 101 ? 108.063 122.958 77.168  1.00 79.53 ? 101 HIS A CB    1 
ATOM   671  C  CG    . HIS A 1 101 ? 108.180 122.577 75.727  1.00 79.53 ? 101 HIS A CG    1 
ATOM   672  N  ND1   . HIS A 1 101 ? 109.388 122.414 75.086  1.00 79.53 ? 101 HIS A ND1   1 
ATOM   673  C  CD2   . HIS A 1 101 ? 107.227 122.309 74.804  1.00 79.53 ? 101 HIS A CD2   1 
ATOM   674  C  CE1   . HIS A 1 101 ? 109.174 122.081 73.825  1.00 79.53 ? 101 HIS A CE1   1 
ATOM   675  N  NE2   . HIS A 1 101 ? 107.870 122.007 73.630  1.00 79.53 ? 101 HIS A NE2   1 
ATOM   676  N  N     . PRO A 1 102 ? 108.331 126.033 79.301  1.00 76.73 ? 102 PRO A N     1 
ATOM   677  C  CA    . PRO A 1 102 ? 107.938 126.470 80.653  1.00 76.73 ? 102 PRO A CA    1 
ATOM   678  C  C     . PRO A 1 102 ? 106.431 126.499 80.896  1.00 76.73 ? 102 PRO A C     1 
ATOM   679  O  O     . PRO A 1 102 ? 106.014 126.784 82.026  1.00 76.73 ? 102 PRO A O     1 
ATOM   680  C  CB    . PRO A 1 102 ? 108.530 127.880 80.757  1.00 76.73 ? 102 PRO A CB    1 
ATOM   681  C  CG    . PRO A 1 102 ? 108.606 128.350 79.361  1.00 76.73 ? 102 PRO A CG    1 
ATOM   682  C  CD    . PRO A 1 102 ? 108.936 127.137 78.538  1.00 76.73 ? 102 PRO A CD    1 
ATOM   683  N  N     . GLU A 1 103 ? 105.605 126.270 79.872  1.00 77.98 ? 103 GLU A N     1 
ATOM   684  C  CA    . GLU A 1 103 ? 104.167 126.114 80.073  1.00 77.98 ? 103 GLU A CA    1 
ATOM   685  C  C     . GLU A 1 103 ? 103.784 124.817 80.774  1.00 77.98 ? 103 GLU A C     1 
ATOM   686  O  O     . GLU A 1 103 ? 102.702 124.754 81.364  1.00 77.98 ? 103 GLU A O     1 
ATOM   687  C  CB    . GLU A 1 103 ? 103.421 126.212 78.737  1.00 77.98 ? 103 GLU A CB    1 
ATOM   688  C  CG    . GLU A 1 103 ? 103.650 125.085 77.729  1.00 77.98 ? 103 GLU A CG    1 
ATOM   689  C  CD    . GLU A 1 103 ? 104.787 125.373 76.757  1.00 77.98 ? 103 GLU A CD    1 
ATOM   690  O  OE1   . GLU A 1 103 ? 105.824 125.920 77.175  1.00 77.98 ? 103 GLU A OE1   1 
ATOM   691  O  OE2   . GLU A 1 103 ? 104.634 125.076 75.554  1.00 77.98 ? 103 GLU A OE2   1 
ATOM   692  N  N     . LEU A 1 104 ? 104.629 123.786 80.723  1.00 69.67 ? 104 LEU A N     1 
ATOM   693  C  CA    . LEU A 1 104 ? 104.291 122.512 81.349  1.00 69.67 ? 104 LEU A CA    1 
ATOM   694  C  C     . LEU A 1 104 ? 104.359 122.578 82.871  1.00 69.67 ? 104 LEU A C     1 
ATOM   695  O  O     . LEU A 1 104 ? 103.530 121.974 83.556  1.00 69.67 ? 104 LEU A O     1 
ATOM   696  C  CB    . LEU A 1 104 ? 105.224 121.420 80.834  1.00 69.67 ? 104 LEU A CB    1 
ATOM   697  C  CG    . LEU A 1 104 ? 105.190 121.041 79.354  1.00 69.67 ? 104 LEU A CG    1 
ATOM   698  C  CD1   . LEU A 1 104 ? 106.296 120.066 79.061  1.00 69.67 ? 104 LEU A CD1   1 
ATOM   699  C  CD2   . LEU A 1 104 ? 103.859 120.434 78.949  1.00 69.67 ? 104 LEU A CD2   1 
ATOM   700  N  N     . PHE A 1 105 ? 105.317 123.316 83.421  1.00 66.05 ? 105 PHE A N     1 
ATOM   701  C  CA    . PHE A 1 105 ? 105.645 123.221 84.844  1.00 66.05 ? 105 PHE A CA    1 
ATOM   702  C  C     . PHE A 1 105 ? 104.655 123.972 85.732  1.00 66.05 ? 105 PHE A C     1 
ATOM   703  O  O     . PHE A 1 105 ? 104.407 125.162 85.531  1.00 66.05 ? 105 PHE A O     1 
ATOM   704  C  CB    . PHE A 1 105 ? 107.077 123.693 85.051  1.00 66.05 ? 105 PHE A CB    1 
ATOM   705  C  CG    . PHE A 1 105 ? 108.091 122.690 84.585  1.00 66.05 ? 105 PHE A CG    1 
ATOM   706  C  CD1   . PHE A 1 105 ? 108.368 122.541 83.241  1.00 66.05 ? 105 PHE A CD1   1 
ATOM   707  C  CD2   . PHE A 1 105 ? 108.748 121.880 85.489  1.00 66.05 ? 105 PHE A CD2   1 
ATOM   708  C  CE1   . PHE A 1 105 ? 109.284 121.606 82.809  1.00 66.05 ? 105 PHE A CE1   1 
ATOM   709  C  CE2   . PHE A 1 105 ? 109.667 120.950 85.059  1.00 66.05 ? 105 PHE A CE2   1 
ATOM   710  C  CZ    . PHE A 1 105 ? 109.937 120.819 83.722  1.00 66.05 ? 105 PHE A CZ    1 
ATOM   711  N  N     . ARG A 1 106 ? 104.080 123.255 86.711  1.00 59.44 ? 106 ARG A N     1 
ATOM   712  C  CA    . ARG A 1 106 ? 103.036 123.758 87.599  1.00 59.44 ? 106 ARG A CA    1 
ATOM   713  C  C     . ARG A 1 106 ? 103.453 123.680 89.062  1.00 59.44 ? 106 ARG A C     1 
ATOM   714  O  O     . ARG A 1 106 ? 104.147 122.754 89.481  1.00 59.44 ? 106 ARG A O     1 
ATOM   715  C  CB    . ARG A 1 106 ? 101.728 122.994 87.391  1.00 59.44 ? 106 ARG A CB    1 
ATOM   716  C  CG    . ARG A 1 106 ? 100.988 123.420 86.143  1.00 59.44 ? 106 ARG A CG    1 
ATOM   717  C  CD    . ARG A 1 106 ? 99.690  122.674 85.959  1.00 59.44 ? 106 ARG A CD    1 
ATOM   718  N  NE    . ARG A 1 106 ? 99.959  121.296 85.589  1.00 59.44 ? 106 ARG A NE    1 
ATOM   719  C  CZ    . ARG A 1 106 ? 99.633  120.760 84.424  1.00 59.44 ? 106 ARG A CZ    1 
ATOM   720  N  NH1   . ARG A 1 106 ? 98.834  121.383 83.576  1.00 59.44 ? 106 ARG A NH1   1 
ATOM   721  N  NH2   . ARG A 1 106 ? 100.111 119.564 84.108  1.00 59.44 ? 106 ARG A NH2   1 
ATOM   722  N  N     . GLU A 1 107 ? 103.010 124.672 89.835  1.00 62.63 ? 107 GLU A N     1 
ATOM   723  C  CA    . GLU A 1 107 ? 103.426 124.825 91.228  1.00 62.63 ? 107 GLU A CA    1 
ATOM   724  C  C     . GLU A 1 107 ? 102.845 123.754 92.147  1.00 62.63 ? 107 GLU A C     1 
ATOM   725  O  O     . GLU A 1 107 ? 101.625 123.623 92.275  1.00 62.63 ? 107 GLU A O     1 
ATOM   726  C  CB    . GLU A 1 107 ? 103.044 126.206 91.739  1.00 62.63 ? 107 GLU A CB    1 
ATOM   727  C  CG    . GLU A 1 107 ? 103.475 126.436 93.175  1.00 62.63 ? 107 GLU A CG    1 
ATOM   728  C  CD    . GLU A 1 107 ? 103.252 127.855 93.639  1.00 62.63 ? 107 GLU A CD    1 
ATOM   729  O  OE1   . GLU A 1 107 ? 103.199 128.769 92.782  1.00 62.63 ? 107 GLU A OE1   1 
ATOM   730  O  OE2   . GLU A 1 107 ? 103.133 128.055 94.865  1.00 62.63 ? 107 GLU A OE2   1 
ATOM   731  N  N     . MET A 1 108 ? 103.726 123.021 92.817  1.00 59.74 ? 108 MET A N     1 
ATOM   732  C  CA    . MET A 1 108 ? 103.326 122.121 93.888  1.00 59.74 ? 108 MET A CA    1 
ATOM   733  C  C     . MET A 1 108 ? 102.957 122.900 95.143  1.00 59.74 ? 108 MET A C     1 
ATOM   734  O  O     . MET A 1 108 ? 103.684 123.806 95.557  1.00 59.74 ? 108 MET A O     1 
ATOM   735  C  CB    . MET A 1 108 ? 104.461 121.161 94.200  1.00 59.74 ? 108 MET A CB    1 
ATOM   736  C  CG    . MET A 1 108 ? 104.043 119.995 95.033  1.00 59.74 ? 108 MET A CG    1 
ATOM   737  S  SD    . MET A 1 108 ? 105.485 119.189 95.663  1.00 59.74 ? 108 MET A SD    1 
ATOM   738  C  CE    . MET A 1 108 ? 105.852 120.381 96.934  1.00 59.74 ? 108 MET A CE    1 
ATOM   739  N  N     . LYS A 1 109 ? 101.830 122.551 95.760  1.00 56.61 ? 109 LYS A N     1 
ATOM   740  C  CA    . LYS A 1 109 ? 101.395 123.204 96.989  1.00 56.61 ? 109 LYS A CA    1 
ATOM   741  C  C     . LYS A 1 109 ? 101.141 122.173 98.083  1.00 56.61 ? 109 LYS A C     1 
ATOM   742  O  O     . LYS A 1 109 ? 100.662 121.070 97.814  1.00 56.61 ? 109 LYS A O     1 
ATOM   743  C  CB    . LYS A 1 109 ? 100.152 124.082 96.734  1.00 56.61 ? 109 LYS A CB    1 
ATOM   744  C  CG    . LYS A 1 109 ? 100.477 125.248 95.803  1.00 56.61 ? 109 LYS A CG    1 
ATOM   745  C  CD    . LYS A 1 109 ? 99.415  126.334 95.748  1.00 56.61 ? 109 LYS A CD    1 
ATOM   746  C  CE    . LYS A 1 109 ? 98.138  125.865 95.066  1.00 56.61 ? 109 LYS A CE    1 
ATOM   747  N  NZ    . LYS A 1 109 ? 97.119  126.953 95.051  1.00 56.61 ? 109 LYS A NZ    1 
ATOM   748  N  N     . LEU A 1 110 ? 101.470 122.549 99.314  1.00 59.12 ? 110 LEU A N     1 
ATOM   749  C  CA    . LEU A 1 110 ? 101.369 121.662 100.466 1.00 59.12 ? 110 LEU A CA    1 
ATOM   750  C  C     . LEU A 1 110 ? 99.915  121.301 100.762 1.00 59.12 ? 110 LEU A C     1 
ATOM   751  O  O     . LEU A 1 110 ? 99.045  122.177 100.807 1.00 59.12 ? 110 LEU A O     1 
ATOM   752  C  CB    . LEU A 1 110 ? 102.027 122.330 101.672 1.00 59.12 ? 110 LEU A CB    1 
ATOM   753  C  CG    . LEU A 1 110 ? 102.211 121.511 102.942 1.00 59.12 ? 110 LEU A CG    1 
ATOM   754  C  CD1   . LEU A 1 110 ? 103.307 120.466 102.738 1.00 59.12 ? 110 LEU A CD1   1 
ATOM   755  C  CD2   . LEU A 1 110 ? 102.541 122.441 104.107 1.00 59.12 ? 110 LEU A CD2   1 
ATOM   756  N  N     . GLU A 1 111 ? 99.649  120.008 100.943 1.00 53.07 ? 111 GLU A N     1 
ATOM   757  C  CA    . GLU A 1 111 ? 98.286  119.508 101.067 1.00 53.07 ? 111 GLU A CA    1 
ATOM   758  C  C     . GLU A 1 111 ? 97.657  119.789 102.434 1.00 53.07 ? 111 GLU A C     1 
ATOM   759  O  O     . GLU A 1 111 ? 98.356  120.013 103.427 1.00 53.07 ? 111 GLU A O     1 
ATOM   760  C  CB    . GLU A 1 111 ? 98.255  118.006 100.793 1.00 53.07 ? 111 GLU A CB    1 
ATOM   761  C  CG    . GLU A 1 111 ? 98.739  117.129 101.922 1.00 53.07 ? 111 GLU A CG    1 
ATOM   762  C  CD    . GLU A 1 111 ? 98.861  115.671 101.506 1.00 53.07 ? 111 GLU A CD    1 
ATOM   763  O  OE1   . GLU A 1 111 ? 98.023  115.209 100.710 1.00 53.07 ? 111 GLU A OE1   1 
ATOM   764  O  OE2   . GLU A 1 111 ? 99.792  114.983 101.974 1.00 53.07 ? 111 GLU A OE2   1 
ATOM   765  N  N     . PRO A 1 112 ? 96.321  119.829 102.485 1.00 43.27 ? 112 PRO A N     1 
ATOM   766  C  CA    . PRO A 1 112 ? 95.623  119.780 103.768 1.00 43.27 ? 112 PRO A CA    1 
ATOM   767  C  C     . PRO A 1 112 ? 95.604  118.384 104.368 1.00 43.27 ? 112 PRO A C     1 
ATOM   768  O  O     . PRO A 1 112 ? 95.705  117.378 103.647 1.00 43.27 ? 112 PRO A O     1 
ATOM   769  C  CB    . PRO A 1 112 ? 94.205  120.257 103.410 1.00 43.27 ? 112 PRO A CB    1 
ATOM   770  C  CG    . PRO A 1 112 ? 94.029  119.780 102.037 1.00 43.27 ? 112 PRO A CG    1 
ATOM   771  C  CD    . PRO A 1 112 ? 95.374  119.908 101.365 1.00 43.27 ? 112 PRO A CD    1 
ATOM   772  N  N     . PRO A 1 113 ? 95.483  118.276 105.698 1.00 35.96 ? 113 PRO A N     1 
ATOM   773  C  CA    . PRO A 1 113 ? 95.504  116.961 106.365 1.00 35.96 ? 113 PRO A CA    1 
ATOM   774  C  C     . PRO A 1 113 ? 94.304  116.065 106.056 1.00 35.96 ? 113 PRO A C     1 
ATOM   775  O  O     . PRO A 1 113 ? 94.377  114.841 106.274 1.00 35.96 ? 113 PRO A O     1 
ATOM   776  C  CB    . PRO A 1 113 ? 95.540  117.332 107.854 1.00 35.96 ? 113 PRO A CB    1 
ATOM   777  C  CG    . PRO A 1 113 ? 94.920  118.651 107.926 1.00 35.96 ? 113 PRO A CG    1 
ATOM   778  C  CD    . PRO A 1 113 ? 95.331  119.367 106.669 1.00 35.96 ? 113 PRO A CD    1 
ATOM   779  N  N     . LEU A 1 114 ? 93.195  116.638 105.588 1.00 31.56 ? 114 LEU A N     1 
ATOM   780  C  CA    . LEU A 1 114 ? 92.080  115.832 105.108 1.00 31.56 ? 114 LEU A CA    1 
ATOM   781  C  C     . LEU A 1 114 ? 92.527  114.805 104.079 1.00 31.56 ? 114 LEU A C     1 
ATOM   782  O  O     . LEU A 1 114 ? 92.051  113.669 104.088 1.00 31.56 ? 114 LEU A O     1 
ATOM   783  C  CB    . LEU A 1 114 ? 90.990  116.726 104.521 1.00 31.56 ? 114 LEU A CB    1 
ATOM   784  C  CG    . LEU A 1 114 ? 89.828  116.007 103.839 1.00 31.56 ? 114 LEU A CG    1 
ATOM   785  C  CD1   . LEU A 1 114 ? 89.091  115.113 104.813 1.00 31.56 ? 114 LEU A CD1   1 
ATOM   786  C  CD2   . LEU A 1 114 ? 88.864  116.963 103.210 1.00 31.56 ? 114 LEU A CD2   1 
ATOM   787  N  N     . SER A 1 115 ? 93.380  115.206 103.141 1.00 31.21 ? 115 SER A N     1 
ATOM   788  C  CA    . SER A 1 115 ? 93.824  114.293 102.094 1.00 31.21 ? 115 SER A CA    1 
ATOM   789  C  C     . SER A 1 115 ? 94.545  113.082 102.652 1.00 31.21 ? 115 SER A C     1 
ATOM   790  O  O     . SER A 1 115 ? 94.387  111.976 102.135 1.00 31.21 ? 115 SER A O     1 
ATOM   791  C  CB    . SER A 1 115 ? 94.733  115.035 101.122 1.00 31.21 ? 115 SER A CB    1 
ATOM   792  O  OG    . SER A 1 115 ? 94.039  116.085 100.479 1.00 31.21 ? 115 SER A OG    1 
ATOM   793  N  N     . SER A 1 116 ? 95.240  113.243 103.771 1.00 29.91 ? 116 SER A N     1 
ATOM   794  C  CA    . SER A 1 116 ? 95.807  112.094 104.462 1.00 29.91 ? 116 SER A CA    1 
ATOM   795  C  C     . SER A 1 116 ? 94.733  111.237 105.115 1.00 29.91 ? 116 SER A C     1 
ATOM   796  O  O     . SER A 1 116 ? 94.771  110.009 105.000 1.00 29.91 ? 116 SER A O     1 
ATOM   797  C  CB    . SER A 1 116 ? 96.854  112.543 105.479 1.00 29.91 ? 116 SER A CB    1 
ATOM   798  O  OG    . SER A 1 116 ? 96.268  113.057 106.654 1.00 29.91 ? 116 SER A OG    1 
ATOM   799  N  N     . TYR A 1 117 ? 93.778  111.843 105.826 1.00 29.61 ? 117 TYR A N     1 
ATOM   800  C  CA    . TYR A 1 117 ? 92.735  110.999 106.420 1.00 29.61 ? 117 TYR A CA    1 
ATOM   801  C  C     . TYR A 1 117 ? 91.947  110.250 105.356 1.00 29.61 ? 117 TYR A C     1 
ATOM   802  O  O     . TYR A 1 117 ? 91.602  109.086 105.544 1.00 29.61 ? 117 TYR A O     1 
ATOM   803  C  CB    . TYR A 1 117 ? 91.755  111.802 107.278 1.00 29.61 ? 117 TYR A CB    1 
ATOM   804  C  CG    . TYR A 1 117 ? 92.332  112.567 108.428 1.00 29.61 ? 117 TYR A CG    1 
ATOM   805  C  CD1   . TYR A 1 117 ? 93.101  111.936 109.382 1.00 29.61 ? 117 TYR A CD1   1 
ATOM   806  C  CD2   . TYR A 1 117 ? 92.092  113.928 108.566 1.00 29.61 ? 117 TYR A CD2   1 
ATOM   807  C  CE1   . TYR A 1 117 ? 93.611  112.620 110.440 1.00 29.61 ? 117 TYR A CE1   1 
ATOM   808  C  CE2   . TYR A 1 117 ? 92.612  114.631 109.617 1.00 29.61 ? 117 TYR A CE2   1 
ATOM   809  C  CZ    . TYR A 1 117 ? 93.375  113.970 110.555 1.00 29.61 ? 117 TYR A CZ    1 
ATOM   810  O  OH    . TYR A 1 117 ? 93.906  114.672 111.610 1.00 29.61 ? 117 TYR A OH    1 
ATOM   811  N  N     . TYR A 1 118 ? 91.621  110.910 104.250 1.00 23.88 ? 118 TYR A N     1 
ATOM   812  C  CA    . TYR A 1 118 ? 90.890  110.268 103.165 1.00 23.88 ? 118 TYR A CA    1 
ATOM   813  C  C     . TYR A 1 118 ? 91.702  109.161 102.508 1.00 23.88 ? 118 TYR A C     1 
ATOM   814  O  O     . TYR A 1 118 ? 91.164  108.097 102.190 1.00 23.88 ? 118 TYR A O     1 
ATOM   815  C  CB    . TYR A 1 118 ? 90.464  111.306 102.134 1.00 23.88 ? 118 TYR A CB    1 
ATOM   816  C  CG    . TYR A 1 118 ? 89.689  110.722 100.993 1.00 23.88 ? 118 TYR A CG    1 
ATOM   817  C  CD1   . TYR A 1 118 ? 88.337  110.455 101.112 1.00 23.88 ? 118 TYR A CD1   1 
ATOM   818  C  CD2   . TYR A 1 118 ? 90.310  110.427 99.795  1.00 23.88 ? 118 TYR A CD2   1 
ATOM   819  C  CE1   . TYR A 1 118 ? 87.639  109.901 100.081 1.00 23.88 ? 118 TYR A CE1   1 
ATOM   820  C  CE2   . TYR A 1 118 ? 89.611  109.880 98.749  1.00 23.88 ? 118 TYR A CE2   1 
ATOM   821  C  CZ    . TYR A 1 118 ? 88.281  109.618 98.900  1.00 23.88 ? 118 TYR A CZ    1 
ATOM   822  O  OH    . TYR A 1 118 ? 87.590  109.094 97.846  1.00 23.88 ? 118 TYR A OH    1 
ATOM   823  N  N     . ALA A 1 119 ? 92.998  109.384 102.306 1.00 20.26 ? 119 ALA A N     1 
ATOM   824  C  CA    . ALA A 1 119 ? 93.867  108.317 101.836 1.00 20.26 ? 119 ALA A CA    1 
ATOM   825  C  C     . ALA A 1 119 ? 93.829  107.119 102.765 1.00 20.26 ? 119 ALA A C     1 
ATOM   826  O  O     . ALA A 1 119 ? 93.705  105.987 102.307 1.00 20.26 ? 119 ALA A O     1 
ATOM   827  C  CB    . ALA A 1 119 ? 95.296  108.827 101.686 1.00 20.26 ? 119 ALA A CB    1 
ATOM   828  N  N     . ILE A 1 120 ? 93.986  107.335 104.068 1.00 22.35 ? 120 ILE A N     1 
ATOM   829  C  CA    . ILE A 1 120 ? 93.994  106.204 104.994 1.00 22.35 ? 120 ILE A CA    1 
ATOM   830  C  C     . ILE A 1 120 ? 92.616  105.556 105.096 1.00 22.35 ? 120 ILE A C     1 
ATOM   831  O  O     . ILE A 1 120 ? 92.507  104.343 105.302 1.00 22.35 ? 120 ILE A O     1 
ATOM   832  C  CB    . ILE A 1 120 ? 94.511  106.612 106.382 1.00 22.35 ? 120 ILE A CB    1 
ATOM   833  C  CG1   . ILE A 1 120 ? 95.798  107.400 106.281 1.00 22.35 ? 120 ILE A CG1   1 
ATOM   834  C  CG2   . ILE A 1 120 ? 94.789  105.395 107.224 1.00 22.35 ? 120 ILE A CG2   1 
ATOM   835  C  CD1   . ILE A 1 120 ? 95.940  108.398 107.391 1.00 22.35 ? 120 ILE A CD1   1 
ATOM   836  N  N     . PHE A 1 121 ? 91.548  106.339 104.965 1.00 20.08 ? 121 PHE A N     1 
ATOM   837  C  CA    . PHE A 1 121 ? 90.203  105.781 104.874 1.00 20.08 ? 121 PHE A CA    1 
ATOM   838  C  C     . PHE A 1 121 ? 90.057  104.830 103.691 1.00 20.08 ? 121 PHE A C     1 
ATOM   839  O  O     . PHE A 1 121 ? 89.600  103.699 103.858 1.00 20.08 ? 121 PHE A O     1 
ATOM   840  C  CB    . PHE A 1 121 ? 89.166  106.910 104.812 1.00 20.08 ? 121 PHE A CB    1 
ATOM   841  C  CG    . PHE A 1 121 ? 87.797  106.454 104.394 1.00 20.08 ? 121 PHE A CG    1 
ATOM   842  C  CD1   . PHE A 1 121 ? 87.031  105.666 105.219 1.00 20.08 ? 121 PHE A CD1   1 
ATOM   843  C  CD2   . PHE A 1 121 ? 87.272  106.829 103.173 1.00 20.08 ? 121 PHE A CD2   1 
ATOM   844  C  CE1   . PHE A 1 121 ? 85.787  105.239 104.824 1.00 20.08 ? 121 PHE A CE1   1 
ATOM   845  C  CE2   . PHE A 1 121 ? 86.026  106.399 102.780 1.00 20.08 ? 121 PHE A CE2   1 
ATOM   846  C  CZ    . PHE A 1 121 ? 85.286  105.611 103.608 1.00 20.08 ? 121 PHE A CZ    1 
ATOM   847  N  N     . LYS A 1 122 ? 90.446  105.265 102.489 1.00 19.20 ? 122 LYS A N     1 
ATOM   848  C  CA    . LYS A 1 122 ? 90.404  104.378 101.323 1.00 19.20 ? 122 LYS A CA    1 
ATOM   849  C  C     . LYS A 1 122 ? 91.419  103.239 101.381 1.00 19.20 ? 122 LYS A C     1 
ATOM   850  O  O     . LYS A 1 122 ? 91.152  102.153 100.856 1.00 19.20 ? 122 LYS A O     1 
ATOM   851  C  CB    . LYS A 1 122 ? 90.606  105.184 100.046 1.00 19.20 ? 122 LYS A CB    1 
ATOM   852  C  CG    . LYS A 1 122 ? 89.407  105.995 99.650  1.00 19.20 ? 122 LYS A CG    1 
ATOM   853  C  CD    . LYS A 1 122 ? 88.271  105.082 99.259  1.00 19.20 ? 122 LYS A CD    1 
ATOM   854  C  CE    . LYS A 1 122 ? 87.059  105.858 98.813  1.00 19.20 ? 122 LYS A CE    1 
ATOM   855  N  NZ    . LYS A 1 122 ? 86.007  104.919 98.389  1.00 19.20 ? 122 LYS A NZ    1 
ATOM   856  N  N     . ASP A 1 123 ? 92.554  103.436 102.039 1.00 17.97 ? 123 ASP A N     1 
ATOM   857  C  CA    . ASP A 1 123 ? 93.481  102.337 102.284 1.00 17.97 ? 123 ASP A CA    1 
ATOM   858  C  C     . ASP A 1 123 ? 92.886  101.276 103.203 1.00 17.97 ? 123 ASP A C     1 
ATOM   859  O  O     . ASP A 1 123 ? 93.110  100.086 102.989 1.00 17.97 ? 123 ASP A O     1 
ATOM   860  C  CB    . ASP A 1 123 ? 94.800  102.862 102.871 1.00 17.97 ? 123 ASP A CB    1 
ATOM   861  C  CG    . ASP A 1 123 ? 95.568  103.805 101.925 1.00 17.97 ? 123 ASP A CG    1 
ATOM   862  O  OD1   . ASP A 1 123 ? 95.347  103.815 100.693 1.00 17.97 ? 123 ASP A OD1   1 
ATOM   863  O  OD2   . ASP A 1 123 ? 96.440  104.536 102.425 1.00 17.97 ? 123 ASP A OD2   1 
ATOM   864  N  N     . TYR A 1 124 ? 92.130  101.675 104.225 1.00 22.04 ? 124 TYR A N     1 
ATOM   865  C  CA    . TYR A 1 124 ? 91.355  100.710 105.005 1.00 22.04 ? 124 TYR A CA    1 
ATOM   866  C  C     . TYR A 1 124 ? 90.180  100.113 104.242 1.00 22.04 ? 124 TYR A C     1 
ATOM   867  O  O     . TYR A 1 124 ? 89.884  98.928  104.396 1.00 22.04 ? 124 TYR A O     1 
ATOM   868  C  CB    . TYR A 1 124 ? 90.822  101.345 106.280 1.00 22.04 ? 124 TYR A CB    1 
ATOM   869  C  CG    . TYR A 1 124 ? 91.686  101.224 107.506 1.00 22.04 ? 124 TYR A CG    1 
ATOM   870  C  CD1   . TYR A 1 124 ? 91.777  100.033 108.192 1.00 22.04 ? 124 TYR A CD1   1 
ATOM   871  C  CD2   . TYR A 1 124 ? 92.328  102.321 108.035 1.00 22.04 ? 124 TYR A CD2   1 
ATOM   872  C  CE1   . TYR A 1 124 ? 92.576  99.917  109.295 1.00 22.04 ? 124 TYR A CE1   1 
ATOM   873  C  CE2   . TYR A 1 124 ? 93.086  102.228 109.169 1.00 22.04 ? 124 TYR A CE2   1 
ATOM   874  C  CZ    . TYR A 1 124 ? 93.217  101.027 109.788 1.00 22.04 ? 124 TYR A CZ    1 
ATOM   875  O  OH    . TYR A 1 124 ? 93.935  100.953 110.952 1.00 22.04 ? 124 TYR A OH    1 
ATOM   876  N  N     . GLN A 1 125 ? 89.466  100.913 103.460 1.00 20.33 ? 125 GLN A N     1 
ATOM   877  C  CA    . GLN A 1 125 ? 88.305  100.400 102.739 1.00 20.33 ? 125 GLN A CA    1 
ATOM   878  C  C     . GLN A 1 125 ? 88.665  99.346  101.706 1.00 20.33 ? 125 GLN A C     1 
ATOM   879  O  O     . GLN A 1 125 ? 87.928  98.375  101.535 1.00 20.33 ? 125 GLN A O     1 
ATOM   880  C  CB    . GLN A 1 125 ? 87.542  101.525 102.071 1.00 20.33 ? 125 GLN A CB    1 
ATOM   881  C  CG    . GLN A 1 125 ? 86.370  100.975 101.312 1.00 20.33 ? 125 GLN A CG    1 
ATOM   882  C  CD    . GLN A 1 125 ? 85.477  102.018 100.733 1.00 20.33 ? 125 GLN A CD    1 
ATOM   883  O  OE1   . GLN A 1 125 ? 85.660  102.446 99.601  1.00 20.33 ? 125 GLN A OE1   1 
ATOM   884  N  NE2   . GLN A 1 125 ? 84.491  102.424 101.495 1.00 20.33 ? 125 GLN A NE2   1 
ATOM   885  N  N     . GLU A 1 126 ? 89.730  99.552  100.937 1.00 22.73 ? 126 GLU A N     1 
ATOM   886  C  CA    . GLU A 1 126 ? 90.119  98.506  99.998  1.00 22.73 ? 126 GLU A CA    1 
ATOM   887  C  C     . GLU A 1 126 ? 90.519  97.227  100.720 1.00 22.73 ? 126 GLU A C     1 
ATOM   888  O  O     . GLU A 1 126 ? 90.196  96.131  100.260 1.00 22.73 ? 126 GLU A O     1 
ATOM   889  C  CB    . GLU A 1 126 ? 91.194  99.023  99.038  1.00 22.73 ? 126 GLU A CB    1 
ATOM   890  C  CG    . GLU A 1 126 ? 92.595  99.229  99.562  1.00 22.73 ? 126 GLU A CG    1 
ATOM   891  C  CD    . GLU A 1 126 ? 93.550  98.091  99.260  1.00 22.73 ? 126 GLU A CD    1 
ATOM   892  O  OE1   . GLU A 1 126 ? 93.109  96.971  98.946  1.00 22.73 ? 126 GLU A OE1   1 
ATOM   893  O  OE2   . GLU A 1 126 ? 94.767  98.336  99.318  1.00 22.73 ? 126 GLU A OE2   1 
ATOM   894  N  N     . VAL A 1 127 ? 91.156  97.340  101.882 1.00 19.27 ? 127 VAL A N     1 
ATOM   895  C  CA    . VAL A 1 127 ? 91.403  96.162  102.711 1.00 19.27 ? 127 VAL A CA    1 
ATOM   896  C  C     . VAL A 1 127 ? 90.106  95.541  103.232 1.00 19.27 ? 127 VAL A C     1 
ATOM   897  O  O     . VAL A 1 127 ? 89.976  94.313  103.298 1.00 19.27 ? 127 VAL A O     1 
ATOM   898  C  CB    . VAL A 1 127 ? 92.344  96.537  103.870 1.00 19.27 ? 127 VAL A CB    1 
ATOM   899  C  CG1   . VAL A 1 127 ? 92.576  95.367  104.775 1.00 19.27 ? 127 VAL A CG1   1 
ATOM   900  C  CG2   . VAL A 1 127 ? 93.663  97.028  103.347 1.00 19.27 ? 127 VAL A CG2   1 
ATOM   901  N  N     . ARG A 1 128 ? 89.097  96.364  103.514 1.00 22.28 ? 128 ARG A N     1 
ATOM   902  C  CA    . ARG A 1 128 ? 87.799  95.861  103.960 1.00 22.28 ? 128 ARG A CA    1 
ATOM   903  C  C     . ARG A 1 128 ? 87.065  95.116  102.856 1.00 22.28 ? 128 ARG A C     1 
ATOM   904  O  O     . ARG A 1 128 ? 86.509  94.047  103.093 1.00 22.28 ? 128 ARG A O     1 
ATOM   905  C  CB    . ARG A 1 128 ? 86.956  97.020  104.506 1.00 22.28 ? 128 ARG A CB    1 
ATOM   906  C  CG    . ARG A 1 128 ? 85.703  96.587  105.239 1.00 22.28 ? 128 ARG A CG    1 
ATOM   907  C  CD    . ARG A 1 128 ? 84.518  96.526  104.328 1.00 22.28 ? 128 ARG A CD    1 
ATOM   908  N  NE    . ARG A 1 128 ? 84.175  97.852  103.842 1.00 22.28 ? 128 ARG A NE    1 
ATOM   909  C  CZ    . ARG A 1 128 ? 83.329  98.079  102.854 1.00 22.28 ? 128 ARG A CZ    1 
ATOM   910  N  NH1   . ARG A 1 128 ? 82.721  97.088  102.235 1.00 22.28 ? 128 ARG A NH1   1 
ATOM   911  N  NH2   . ARG A 1 128 ? 83.091  99.331  102.480 1.00 22.28 ? 128 ARG A NH2   1 
ATOM   912  N  N     . ILE A 1 129 ? 86.996  95.704  101.666 1.00 34.16 ? 129 ILE A N     1 
ATOM   913  C  CA    . ILE A 1 129 ? 86.341  95.079  100.519 1.00 34.16 ? 129 ILE A CA    1 
ATOM   914  C  C     . ILE A 1 129 ? 87.051  93.793  100.132 1.00 34.16 ? 129 ILE A C     1 
ATOM   915  O  O     . ILE A 1 129 ? 86.429  92.751  99.916  1.00 34.16 ? 129 ILE A O     1 
ATOM   916  C  CB    . ILE A 1 129 ? 86.288  96.061  99.340  1.00 34.16 ? 129 ILE A CB    1 
ATOM   917  C  CG1   . ILE A 1 129 ? 85.390  97.234  99.668  1.00 34.16 ? 129 ILE A CG1   1 
ATOM   918  C  CG2   . ILE A 1 129 ? 85.784  95.371  98.120  1.00 34.16 ? 129 ILE A CG2   1 
ATOM   919  C  CD1   . ILE A 1 129 ? 85.496  98.358  98.730  1.00 34.16 ? 129 ILE A CD1   1 
ATOM   920  N  N     . ARG A 1 130 ? 88.361  93.876  99.973  1.00 20.63 ? 130 ARG A N     1 
ATOM   921  C  CA    . ARG A 1 130 ? 89.233  92.725  99.820  1.00 20.63 ? 130 ARG A CA    1 
ATOM   922  C  C     . ARG A 1 130 ? 88.955  91.605  100.818 1.00 20.63 ? 130 ARG A C     1 
ATOM   923  O  O     . ARG A 1 130 ? 88.996  90.428  100.455 1.00 20.63 ? 130 ARG A O     1 
ATOM   924  C  CB    . ARG A 1 130 ? 90.647  93.275  99.970  1.00 20.63 ? 130 ARG A CB    1 
ATOM   925  C  CG    . ARG A 1 130 ? 91.771  92.353  100.093 1.00 20.63 ? 130 ARG A CG    1 
ATOM   926  C  CD    . ARG A 1 130 ? 93.038  93.178  100.284 1.00 20.63 ? 130 ARG A CD    1 
ATOM   927  N  NE    . ARG A 1 130 ? 93.311  94.060  99.164  1.00 20.63 ? 130 ARG A NE    1 
ATOM   928  C  CZ    . ARG A 1 130 ? 93.568  93.657  97.933  1.00 20.63 ? 130 ARG A CZ    1 
ATOM   929  N  NH1   . ARG A 1 130 ? 93.933  92.418  97.677  1.00 20.63 ? 130 ARG A NH1   1 
ATOM   930  N  NH2   . ARG A 1 130 ? 93.560  94.545  96.947  1.00 20.63 ? 130 ARG A NH2   1 
ATOM   931  N  N     . THR A 1 131 ? 88.680  91.945  102.081 1.00 22.86 ? 131 THR A N     1 
ATOM   932  C  CA    . THR A 1 131 ? 88.406  90.941  103.114 1.00 22.86 ? 131 THR A CA    1 
ATOM   933  C  C     . THR A 1 131 ? 86.973  90.399  103.057 1.00 22.86 ? 131 THR A C     1 
ATOM   934  O  O     . THR A 1 131 ? 86.734  89.200  103.284 1.00 22.86 ? 131 THR A O     1 
ATOM   935  C  CB    . THR A 1 131 ? 88.688  91.551  104.485 1.00 22.86 ? 131 THR A CB    1 
ATOM   936  O  OG1   . THR A 1 131 ? 90.026  92.048  104.504 1.00 22.86 ? 131 THR A OG1   1 
ATOM   937  C  CG2   . THR A 1 131 ? 88.578  90.505  105.561 1.00 22.86 ? 131 THR A CG2   1 
ATOM   938  N  N     . GLY A 1 132 ? 86.014  91.274  102.757 1.00 23.20 ? 132 GLY A N     1 
ATOM   939  C  CA    . GLY A 1 132 ? 84.652  90.839  102.518 1.00 23.20 ? 132 GLY A CA    1 
ATOM   940  C  C     . GLY A 1 132 ? 84.514  89.861  101.369 1.00 23.20 ? 132 GLY A C     1 
ATOM   941  O  O     . GLY A 1 132 ? 83.768  88.884  101.461 1.00 23.20 ? 132 GLY A O     1 
ATOM   942  N  N     . ASN A 1 133 ? 85.224  90.106  100.274 1.00 21.69 ? 133 ASN A N     1 
ATOM   943  C  CA    . ASN A 1 133 ? 85.157  89.196  99.140  1.00 21.69 ? 133 ASN A CA    1 
ATOM   944  C  C     . ASN A 1 133 ? 85.703  87.815  99.470  1.00 21.69 ? 133 ASN A C     1 
ATOM   945  O  O     . ASN A 1 133 ? 85.190  86.799  98.980  1.00 21.69 ? 133 ASN A O     1 
ATOM   946  C  CB    . ASN A 1 133 ? 85.943  89.800  97.988  1.00 21.69 ? 133 ASN A CB    1 
ATOM   947  C  CG    . ASN A 1 133 ? 85.294  91.030  97.427  1.00 21.69 ? 133 ASN A CG    1 
ATOM   948  O  OD1   . ASN A 1 133 ? 84.278  91.486  97.918  1.00 21.69 ? 133 ASN A OD1   1 
ATOM   949  N  ND2   . ASN A 1 133 ? 85.895  91.591  96.407  1.00 21.69 ? 133 ASN A ND2   1 
ATOM   950  N  N     . ARG A 1 134 ? 86.679  87.740  100.361 1.00 24.15 ? 134 ARG A N     1 
ATOM   951  C  CA    . ARG A 1 134 ? 87.184  86.446  100.790 1.00 24.15 ? 134 ARG A CA    1 
ATOM   952  C  C     . ARG A 1 134 ? 86.215  85.751  101.733 1.00 24.15 ? 134 ARG A C     1 
ATOM   953  O  O     . ARG A 1 134 ? 86.067  84.527  101.685 1.00 24.15 ? 134 ARG A O     1 
ATOM   954  C  CB    . ARG A 1 134 ? 88.562  86.632  101.408 1.00 24.15 ? 134 ARG A CB    1 
ATOM   955  C  CG    . ARG A 1 134 ? 89.554  87.083  100.341 1.00 24.15 ? 134 ARG A CG    1 
ATOM   956  C  CD    . ARG A 1 134 ? 91.000  87.034  100.734 1.00 24.15 ? 134 ARG A CD    1 
ATOM   957  N  NE    . ARG A 1 134 ? 91.551  88.338  101.070 1.00 24.15 ? 134 ARG A NE    1 
ATOM   958  C  CZ    . ARG A 1 134 ? 92.585  88.903  100.464 1.00 24.15 ? 134 ARG A CZ    1 
ATOM   959  N  NH1   . ARG A 1 134 ? 93.007  88.497  99.287  1.00 24.15 ? 134 ARG A NH1   1 
ATOM   960  N  NH2   . ARG A 1 134 ? 93.173  89.945  101.028 1.00 24.15 ? 134 ARG A NH2   1 
ATOM   961  N  N     . LEU A 1 135 ? 85.555  86.509  102.604 1.00 26.94 ? 135 LEU A N     1 
ATOM   962  C  CA    . LEU A 1 135 ? 84.447  85.962  103.390 1.00 26.94 ? 135 LEU A CA    1 
ATOM   963  C  C     . LEU A 1 135 ? 83.283  85.492  102.530 1.00 26.94 ? 135 LEU A C     1 
ATOM   964  O  O     . LEU A 1 135 ? 82.530  84.608  102.945 1.00 26.94 ? 135 LEU A O     1 
ATOM   965  C  CB    . LEU A 1 135 ? 83.956  87.010  104.381 1.00 26.94 ? 135 LEU A CB    1 
ATOM   966  C  CG    . LEU A 1 135 ? 84.348  86.853  105.837 1.00 26.94 ? 135 LEU A CG    1 
ATOM   967  C  CD1   . LEU A 1 135 ? 85.748  86.433  105.942 1.00 26.94 ? 135 LEU A CD1   1 
ATOM   968  C  CD2   . LEU A 1 135 ? 84.200  88.217  106.453 1.00 26.94 ? 135 LEU A CD2   1 
ATOM   969  N  N     . TYR A 1 136 ? 83.100  86.072  101.352 1.00 26.66 ? 136 TYR A N     1 
ATOM   970  C  CA    . TYR A 1 136 ? 82.146  85.504  100.409 1.00 26.66 ? 136 TYR A CA    1 
ATOM   971  C  C     . TYR A 1 136 ? 82.646  84.185  99.843  1.00 26.66 ? 136 TYR A C     1 
ATOM   972  O  O     . TYR A 1 136 ? 81.856  83.273  99.593  1.00 26.66 ? 136 TYR A O     1 
ATOM   973  C  CB    . TYR A 1 136 ? 81.856  86.490  99.286  1.00 26.66 ? 136 TYR A CB    1 
ATOM   974  C  CG    . TYR A 1 136 ? 80.802  86.008  98.322  1.00 26.66 ? 136 TYR A CG    1 
ATOM   975  C  CD1   . TYR A 1 136 ? 81.124  85.168  97.264  1.00 26.66 ? 136 TYR A CD1   1 
ATOM   976  C  CD2   . TYR A 1 136 ? 79.486  86.399  98.461  1.00 26.66 ? 136 TYR A CD2   1 
ATOM   977  C  CE1   . TYR A 1 136 ? 80.166  84.717  96.396  1.00 26.66 ? 136 TYR A CE1   1 
ATOM   978  C  CE2   . TYR A 1 136 ? 78.525  85.960  97.587  1.00 26.66 ? 136 TYR A CE2   1 
ATOM   979  C  CZ    . TYR A 1 136 ? 78.867  85.122  96.557  1.00 26.66 ? 136 TYR A CZ    1 
ATOM   980  O  OH    . TYR A 1 136 ? 77.901  84.697  95.682  1.00 26.66 ? 136 TYR A OH    1 
ATOM   981  N  N     . SER A 1 137 ? 83.944  84.069  99.612  1.00 30.49 ? 137 SER A N     1 
ATOM   982  C  CA    . SER A 1 137 ? 84.443  82.932  98.848  1.00 30.49 ? 137 SER A CA    1 
ATOM   983  C  C     . SER A 1 137 ? 84.610  81.670  99.694  1.00 30.49 ? 137 SER A C     1 
ATOM   984  O  O     . SER A 1 137 ? 84.345  80.568  99.209  1.00 30.49 ? 137 SER A O     1 
ATOM   985  C  CB    . SER A 1 137 ? 85.738  83.319  98.159  1.00 30.49 ? 137 SER A CB    1 
ATOM   986  O  OG    . SER A 1 137 ? 85.525  84.440  97.318  1.00 30.49 ? 137 SER A OG    1 
ATOM   987  N  N     . ASP A 1 138 ? 85.083  81.787  100.932 1.00 40.42 ? 138 ASP A N     1 
ATOM   988  C  CA    . ASP A 1 138 ? 84.866  80.733  101.921 1.00 40.42 ? 138 ASP A CA    1 
ATOM   989  C  C     . ASP A 1 138 ? 85.067  81.325  103.305 1.00 40.42 ? 138 ASP A C     1 
ATOM   990  O  O     . ASP A 1 138 ? 85.712  82.362  103.463 1.00 40.42 ? 138 ASP A O     1 
ATOM   991  C  CB    . ASP A 1 138 ? 85.790  79.521  101.687 1.00 40.42 ? 138 ASP A CB    1 
ATOM   992  C  CG    . ASP A 1 138 ? 85.093  78.164  101.966 1.00 40.42 ? 138 ASP A CG    1 
ATOM   993  O  OD1   . ASP A 1 138 ? 84.354  78.029  102.971 1.00 40.42 ? 138 ASP A OD1   1 
ATOM   994  O  OD2   . ASP A 1 138 ? 85.256  77.234  101.147 1.00 40.42 ? 138 ASP A OD2   1 
ATOM   995  N  N     . ARG A 1 139 ? 84.511  80.644  104.308 1.00 38.49 ? 139 ARG A N     1 
ATOM   996  C  CA    . ARG A 1 139 ? 84.265  81.214  105.631 1.00 38.49 ? 139 ARG A CA    1 
ATOM   997  C  C     . ARG A 1 139 ? 85.208  80.649  106.681 1.00 38.49 ? 139 ARG A C     1 
ATOM   998  O  O     . ARG A 1 139 ? 85.262  79.433  106.884 1.00 38.49 ? 139 ARG A O     1 
ATOM   999  C  CB    . ARG A 1 139 ? 82.822  80.955  106.054 1.00 38.49 ? 139 ARG A CB    1 
ATOM   1000 C  CG    . ARG A 1 139 ? 82.235  82.065  106.864 1.00 38.49 ? 139 ARG A CG    1 
ATOM   1001 C  CD    . ARG A 1 139 ? 81.954  83.254  105.974 1.00 38.49 ? 139 ARG A CD    1 
ATOM   1002 N  NE    . ARG A 1 139 ? 81.366  84.357  106.715 1.00 38.49 ? 139 ARG A NE    1 
ATOM   1003 C  CZ    . ARG A 1 139 ? 80.527  85.239  106.197 1.00 38.49 ? 139 ARG A CZ    1 
ATOM   1004 N  NH1   . ARG A 1 139 ? 80.220  85.227  104.913 1.00 38.49 ? 139 ARG A NH1   1 
ATOM   1005 N  NH2   . ARG A 1 139 ? 80.008  86.177  106.983 1.00 38.49 ? 139 ARG A NH2   1 
ATOM   1006 N  N     . THR A 1 140 ? 85.920  81.542  107.369 1.00 36.87 ? 140 THR A N     1 
ATOM   1007 C  CA    . THR A 1 140 ? 86.784  81.201  108.492 1.00 36.87 ? 140 THR A CA    1 
ATOM   1008 C  C     . THR A 1 140 ? 86.803  82.350  109.494 1.00 36.87 ? 140 THR A C     1 
ATOM   1009 O  O     . THR A 1 140 ? 86.680  83.518  109.122 1.00 36.87 ? 140 THR A O     1 
ATOM   1010 C  CB    . THR A 1 140 ? 88.210  80.859  108.028 1.00 36.87 ? 140 THR A CB    1 
ATOM   1011 O  OG1   . THR A 1 140 ? 88.651  81.822  107.064 1.00 36.87 ? 140 THR A OG1   1 
ATOM   1012 C  CG2   . THR A 1 140 ? 88.306  79.446  107.462 1.00 36.87 ? 140 THR A CG2   1 
ATOM   1013 N  N     . ASP A 1 141 ? 86.946  82.005  110.779 1.00 35.96 ? 141 ASP A N     1 
ATOM   1014 C  CA    . ASP A 1 141 ? 86.870  83.012  111.840 1.00 35.96 ? 141 ASP A CA    1 
ATOM   1015 C  C     . ASP A 1 141 ? 88.029  84.003  111.816 1.00 35.96 ? 141 ASP A C     1 
ATOM   1016 O  O     . ASP A 1 141 ? 87.862  85.154  112.239 1.00 35.96 ? 141 ASP A O     1 
ATOM   1017 C  CB    . ASP A 1 141 ? 86.812  82.335  113.208 1.00 35.96 ? 141 ASP A CB    1 
ATOM   1018 C  CG    . ASP A 1 141 ? 85.556  81.511  113.400 1.00 35.96 ? 141 ASP A CG    1 
ATOM   1019 O  OD1   . ASP A 1 141 ? 84.673  81.560  112.514 1.00 35.96 ? 141 ASP A OD1   1 
ATOM   1020 O  OD2   . ASP A 1 141 ? 85.452  80.807  114.432 1.00 35.96 ? 141 ASP A OD2   1 
ATOM   1021 N  N     . ALA A 1 142 ? 89.206  83.576  111.359 1.00 31.15 ? 142 ALA A N     1 
ATOM   1022 C  CA    . ALA A 1 142 ? 90.371  84.456  111.335 1.00 31.15 ? 142 ALA A CA    1 
ATOM   1023 C  C     . ALA A 1 142 ? 90.116  85.711  110.507 1.00 31.15 ? 142 ALA A C     1 
ATOM   1024 O  O     . ALA A 1 142 ? 90.329  86.840  110.972 1.00 31.15 ? 142 ALA A O     1 
ATOM   1025 C  CB    . ALA A 1 142 ? 91.579  83.683  110.805 1.00 31.15 ? 142 ALA A CB    1 
ATOM   1026 N  N     . MET A 1 143 ? 89.557  85.537  109.318 1.00 30.46 ? 143 MET A N     1 
ATOM   1027 C  CA    . MET A 1 143 ? 89.182  86.664  108.482 1.00 30.46 ? 143 MET A CA    1 
ATOM   1028 C  C     . MET A 1 143 ? 87.923  87.372  108.957 1.00 30.46 ? 143 MET A C     1 
ATOM   1029 O  O     . MET A 1 143 ? 87.747  88.541  108.627 1.00 30.46 ? 143 MET A O     1 
ATOM   1030 C  CB    . MET A 1 143 ? 89.009  86.217  107.030 1.00 30.46 ? 143 MET A CB    1 
ATOM   1031 C  CG    . MET A 1 143 ? 90.278  85.714  106.366 1.00 30.46 ? 143 MET A CG    1 
ATOM   1032 S  SD    . MET A 1 143 ? 91.541  86.986  106.193 1.00 30.46 ? 143 MET A SD    1 
ATOM   1033 C  CE    . MET A 1 143 ? 90.922  87.827  104.747 1.00 30.46 ? 143 MET A CE    1 
ATOM   1034 N  N     . GLU A 1 144 ? 87.049  86.719  109.725 1.00 32.15 ? 144 GLU A N     1 
ATOM   1035 C  CA    . GLU A 1 144 ? 85.901  87.438  110.280 1.00 32.15 ? 144 GLU A CA    1 
ATOM   1036 C  C     . GLU A 1 144 ? 86.295  88.407  111.392 1.00 32.15 ? 144 GLU A C     1 
ATOM   1037 O  O     . GLU A 1 144 ? 85.812  89.550  111.424 1.00 32.15 ? 144 GLU A O     1 
ATOM   1038 C  CB    . GLU A 1 144 ? 84.858  86.448  110.783 1.00 32.15 ? 144 GLU A CB    1 
ATOM   1039 C  CG    . GLU A 1 144 ? 84.079  85.786  109.677 1.00 32.15 ? 144 GLU A CG    1 
ATOM   1040 C  CD    . GLU A 1 144 ? 82.788  85.163  110.152 1.00 32.15 ? 144 GLU A CD    1 
ATOM   1041 O  OE1   . GLU A 1 144 ? 82.727  84.730  111.320 1.00 32.15 ? 144 GLU A OE1   1 
ATOM   1042 O  OE2   . GLU A 1 144 ? 81.829  85.116  109.356 1.00 32.15 ? 144 GLU A OE2   1 
ATOM   1043 N  N     . GLU A 1 145 ? 87.211  88.010  112.277 1.00 30.13 ? 145 GLU A N     1 
ATOM   1044 C  CA    . GLU A 1 145 ? 87.719  88.970  113.255 1.00 30.13 ? 145 GLU A CA    1 
ATOM   1045 C  C     . GLU A 1 145 ? 88.580  90.034  112.600 1.00 30.13 ? 145 GLU A C     1 
ATOM   1046 O  O     . GLU A 1 145 ? 88.533  91.209  112.992 1.00 30.13 ? 145 GLU A O     1 
ATOM   1047 C  CB    . GLU A 1 145 ? 88.511  88.279  114.353 1.00 30.13 ? 145 GLU A CB    1 
ATOM   1048 C  CG    . GLU A 1 145 ? 89.094  89.270  115.377 1.00 30.13 ? 145 GLU A CG    1 
ATOM   1049 C  CD    . GLU A 1 145 ? 88.048  90.171  116.043 1.00 30.13 ? 145 GLU A CD    1 
ATOM   1050 O  OE1   . GLU A 1 145 ? 86.878  89.754  116.184 1.00 30.13 ? 145 GLU A OE1   1 
ATOM   1051 O  OE2   . GLU A 1 145 ? 88.406  91.307  116.423 1.00 30.13 ? 145 GLU A OE2   1 
ATOM   1052 N  N     . PHE A 1 146 ? 89.375  89.654  111.606 1.00 25.05 ? 146 PHE A N     1 
ATOM   1053 C  CA    . PHE A 1 146 ? 90.087  90.683  110.871 1.00 25.05 ? 146 PHE A CA    1 
ATOM   1054 C  C     . PHE A 1 146 ? 89.129  91.658  110.207 1.00 25.05 ? 146 PHE A C     1 
ATOM   1055 O  O     . PHE A 1 146 ? 89.370  92.866  110.222 1.00 25.05 ? 146 PHE A O     1 
ATOM   1056 C  CB    . PHE A 1 146 ? 91.019  90.065  109.839 1.00 25.05 ? 146 PHE A CB    1 
ATOM   1057 C  CG    . PHE A 1 146 ? 91.930  91.063  109.208 1.00 25.05 ? 146 PHE A CG    1 
ATOM   1058 C  CD1   . PHE A 1 146 ? 92.819  91.777  109.975 1.00 25.05 ? 146 PHE A CD1   1 
ATOM   1059 C  CD2   . PHE A 1 146 ? 91.882  91.302  107.855 1.00 25.05 ? 146 PHE A CD2   1 
ATOM   1060 C  CE1   . PHE A 1 146 ? 93.638  92.698  109.402 1.00 25.05 ? 146 PHE A CE1   1 
ATOM   1061 C  CE2   . PHE A 1 146 ? 92.705  92.231  107.281 1.00 25.05 ? 146 PHE A CE2   1 
ATOM   1062 C  CZ    . PHE A 1 146 ? 93.579  92.927  108.049 1.00 25.05 ? 146 PHE A CZ    1 
ATOM   1063 N  N     . PHE A 1 147 ? 88.063  91.148  109.589 1.00 25.75 ? 147 PHE A N     1 
ATOM   1064 C  CA    . PHE A 1 147 ? 87.055  91.984  108.949 1.00 25.75 ? 147 PHE A CA    1 
ATOM   1065 C  C     . PHE A 1 147 ? 86.452  92.974  109.922 1.00 25.75 ? 147 PHE A C     1 
ATOM   1066 O  O     . PHE A 1 147 ? 86.237  94.139  109.581 1.00 25.75 ? 147 PHE A O     1 
ATOM   1067 C  CB    . PHE A 1 147 ? 85.972  91.082  108.342 1.00 25.75 ? 147 PHE A CB    1 
ATOM   1068 C  CG    . PHE A 1 147 ? 84.894  91.817  107.596 1.00 25.75 ? 147 PHE A CG    1 
ATOM   1069 C  CD1   . PHE A 1 147 ? 85.179  92.490  106.428 1.00 25.75 ? 147 PHE A CD1   1 
ATOM   1070 C  CD2   . PHE A 1 147 ? 83.596  91.810  108.047 1.00 25.75 ? 147 PHE A CD2   1 
ATOM   1071 C  CE1   . PHE A 1 147 ? 84.205  93.158  105.738 1.00 25.75 ? 147 PHE A CE1   1 
ATOM   1072 C  CE2   . PHE A 1 147 ? 82.611  92.477  107.352 1.00 25.75 ? 147 PHE A CE2   1 
ATOM   1073 C  CZ    . PHE A 1 147 ? 82.920  93.145  106.196 1.00 25.75 ? 147 PHE A CZ    1 
ATOM   1074 N  N     . LYS A 1 148 ? 86.201  92.531  111.148 1.00 27.04 ? 148 LYS A N     1 
ATOM   1075 C  CA    . LYS A 1 148 ? 85.676  93.415  112.184 1.00 27.04 ? 148 LYS A CA    1 
ATOM   1076 C  C     . LYS A 1 148 ? 86.676  94.500  112.602 1.00 27.04 ? 148 LYS A C     1 
ATOM   1077 O  O     . LYS A 1 148 ? 86.301  95.671  112.747 1.00 27.04 ? 148 LYS A O     1 
ATOM   1078 C  CB    . LYS A 1 148 ? 85.232  92.560  113.363 1.00 27.04 ? 148 LYS A CB    1 
ATOM   1079 C  CG    . LYS A 1 148 ? 84.204  93.188  114.253 1.00 27.04 ? 148 LYS A CG    1 
ATOM   1080 C  CD    . LYS A 1 148 ? 83.712  92.184  115.272 1.00 27.04 ? 148 LYS A CD    1 
ATOM   1081 C  CE    . LYS A 1 148 ? 82.890  91.084  114.611 1.00 27.04 ? 148 LYS A CE    1 
ATOM   1082 N  NZ    . LYS A 1 148 ? 81.482  91.494  114.327 1.00 27.04 ? 148 LYS A NZ    1 
ATOM   1083 N  N     . ILE A 1 149 ? 87.956  94.151  112.742 1.00 24.48 ? 149 ILE A N     1 
ATOM   1084 C  CA    . ILE A 1 149 ? 88.982  95.162  113.022 1.00 24.48 ? 149 ILE A CA    1 
ATOM   1085 C  C     . ILE A 1 149 ? 89.111  96.172  111.887 1.00 24.48 ? 149 ILE A C     1 
ATOM   1086 O  O     . ILE A 1 149 ? 89.238  97.383  112.116 1.00 24.48 ? 149 ILE A O     1 
ATOM   1087 C  CB    . ILE A 1 149 ? 90.342  94.489  113.269 1.00 24.48 ? 149 ILE A CB    1 
ATOM   1088 C  CG1   . ILE A 1 149 ? 90.309  93.563  114.467 1.00 24.48 ? 149 ILE A CG1   1 
ATOM   1089 C  CG2   . ILE A 1 149 ? 91.413  95.537  113.470 1.00 24.48 ? 149 ILE A CG2   1 
ATOM   1090 C  CD1   . ILE A 1 149 ? 91.407  92.574  114.431 1.00 24.48 ? 149 ILE A CD1   1 
ATOM   1091 N  N     . VAL A 1 150 ? 89.124  95.686  110.652 1.00 24.84 ? 150 VAL A N     1 
ATOM   1092 C  CA    . VAL A 1 150 ? 89.272  96.558  109.494 1.00 24.84 ? 150 VAL A CA    1 
ATOM   1093 C  C     . VAL A 1 150 ? 88.068  97.476  109.338 1.00 24.84 ? 150 VAL A C     1 
ATOM   1094 O  O     . VAL A 1 150 ? 88.216  98.658  109.009 1.00 24.84 ? 150 VAL A O     1 
ATOM   1095 C  CB    . VAL A 1 150 ? 89.508  95.715  108.233 1.00 24.84 ? 150 VAL A CB    1 
ATOM   1096 C  CG1   . VAL A 1 150 ? 89.619  96.599  107.044 1.00 24.84 ? 150 VAL A CG1   1 
ATOM   1097 C  CG2   . VAL A 1 150 ? 90.730  94.880  108.381 1.00 24.84 ? 150 VAL A CG2   1 
ATOM   1098 N  N     . LYS A 1 151 ? 86.860  96.944  109.549 1.00 26.74 ? 151 LYS A N     1 
ATOM   1099 C  CA    . LYS A 1 151 ? 85.661  97.774  109.622 1.00 26.74 ? 151 LYS A CA    1 
ATOM   1100 C  C     . LYS A 1 151 ? 85.746  98.845  110.697 1.00 26.74 ? 151 LYS A C     1 
ATOM   1101 O  O     . LYS A 1 151 ? 85.321  99.979  110.469 1.00 26.74 ? 151 LYS A O     1 
ATOM   1102 C  CB    . LYS A 1 151 ? 84.430  96.908  109.857 1.00 26.74 ? 151 LYS A CB    1 
ATOM   1103 C  CG    . LYS A 1 151 ? 83.775  96.411  108.609 1.00 26.74 ? 151 LYS A CG    1 
ATOM   1104 C  CD    . LYS A 1 151 ? 82.672  95.432  108.927 1.00 26.74 ? 151 LYS A CD    1 
ATOM   1105 C  CE    . LYS A 1 151 ? 81.620  96.008  109.844 1.00 26.74 ? 151 LYS A CE    1 
ATOM   1106 N  NZ    . LYS A 1 151 ? 80.757  97.013  109.173 1.00 26.74 ? 151 LYS A NZ    1 
ATOM   1107 N  N     . LYS A 1 152 ? 86.272  98.516  111.881 1.00 29.25 ? 152 LYS A N     1 
ATOM   1108 C  CA    . LYS A 1 152 ? 86.479  99.563  112.881 1.00 29.25 ? 152 LYS A CA    1 
ATOM   1109 C  C     . LYS A 1 152 ? 87.441  100.645 112.414 1.00 29.25 ? 152 LYS A C     1 
ATOM   1110 O  O     . LYS A 1 152 ? 87.206  101.828 112.653 1.00 29.25 ? 152 LYS A O     1 
ATOM   1111 C  CB    . LYS A 1 152 ? 86.984  98.985  114.193 1.00 29.25 ? 152 LYS A CB    1 
ATOM   1112 C  CG    . LYS A 1 152 ? 87.082  100.084 115.239 1.00 29.25 ? 152 LYS A CG    1 
ATOM   1113 C  CD    . LYS A 1 152 ? 87.520  99.609  116.594 1.00 29.25 ? 152 LYS A CD    1 
ATOM   1114 C  CE    . LYS A 1 152 ? 87.598  100.782 117.544 1.00 29.25 ? 152 LYS A CE    1 
ATOM   1115 N  NZ    . LYS A 1 152 ? 87.979  100.377 118.918 1.00 29.25 ? 152 LYS A NZ    1 
ATOM   1116 N  N     . GLY A 1 153 ? 88.559  100.267 111.810 1.00 29.60 ? 153 GLY A N     1 
ATOM   1117 C  CA    . GLY A 1 153 ? 89.462  101.281 111.281 1.00 29.60 ? 153 GLY A CA    1 
ATOM   1118 C  C     . GLY A 1 153 ? 88.825  102.165 110.225 1.00 29.60 ? 153 GLY A C     1 
ATOM   1119 O  O     . GLY A 1 153 ? 88.990  103.390 110.238 1.00 29.60 ? 153 GLY A O     1 
ATOM   1120 N  N     . GLU A 1 154 ? 88.077  101.554 109.306 1.00 27.84 ? 154 GLU A N     1 
ATOM   1121 C  CA    . GLU A 1 154 ? 87.344  102.304 108.295 1.00 27.84 ? 154 GLU A CA    1 
ATOM   1122 C  C     . GLU A 1 154 ? 86.332  103.248 108.931 1.00 27.84 ? 154 GLU A C     1 
ATOM   1123 O  O     . GLU A 1 154 ? 86.197  104.402 108.513 1.00 27.84 ? 154 GLU A O     1 
ATOM   1124 C  CB    . GLU A 1 154 ? 86.661  101.329 107.335 1.00 27.84 ? 154 GLU A CB    1 
ATOM   1125 C  CG    . GLU A 1 154 ? 85.989  101.978 106.139 1.00 27.84 ? 154 GLU A CG    1 
ATOM   1126 C  CD    . GLU A 1 154 ? 85.157  101.005 105.339 1.00 27.84 ? 154 GLU A CD    1 
ATOM   1127 O  OE1   . GLU A 1 154 ? 85.054  99.835  105.739 1.00 27.84 ? 154 GLU A OE1   1 
ATOM   1128 O  OE2   . GLU A 1 154 ? 84.565  101.415 104.326 1.00 27.84 ? 154 GLU A OE2   1 
ATOM   1129 N  N     . HIS A 1 155 ? 85.639  102.782 109.966 1.00 31.13 ? 155 HIS A N     1 
ATOM   1130 C  CA    . HIS A 1 155 ? 84.668  103.592 110.695 1.00 31.13 ? 155 HIS A CA    1 
ATOM   1131 C  C     . HIS A 1 155 ? 85.312  104.767 111.417 1.00 31.13 ? 155 HIS A C     1 
ATOM   1132 O  O     . HIS A 1 155 ? 84.861  105.911 111.287 1.00 31.13 ? 155 HIS A O     1 
ATOM   1133 C  CB    . HIS A 1 155 ? 83.934  102.684 111.680 1.00 31.13 ? 155 HIS A CB    1 
ATOM   1134 C  CG    . HIS A 1 155 ? 82.862  103.360 112.472 1.00 31.13 ? 155 HIS A CG    1 
ATOM   1135 N  ND1   . HIS A 1 155 ? 81.738  103.915 111.900 1.00 31.13 ? 155 HIS A ND1   1 
ATOM   1136 C  CD2   . HIS A 1 155 ? 82.725  103.528 113.808 1.00 31.13 ? 155 HIS A CD2   1 
ATOM   1137 C  CE1   . HIS A 1 155 ? 80.966  104.414 112.848 1.00 31.13 ? 155 HIS A CE1   1 
ATOM   1138 N  NE2   . HIS A 1 155 ? 81.544  104.195 114.014 1.00 31.13 ? 155 HIS A NE2   1 
ATOM   1139 N  N     . GLU A 1 156 ? 86.360  104.507 112.188 1.00 32.50 ? 156 GLU A N     1 
ATOM   1140 C  CA    . GLU A 1 156 ? 87.072  105.572 112.884 1.00 32.50 ? 156 GLU A CA    1 
ATOM   1141 C  C     . GLU A 1 156 ? 87.654  106.616 111.939 1.00 32.50 ? 156 GLU A C     1 
ATOM   1142 O  O     . GLU A 1 156 ? 87.620  107.812 112.236 1.00 32.50 ? 156 GLU A O     1 
ATOM   1143 C  CB    . GLU A 1 156 ? 88.180  104.968 113.737 1.00 32.50 ? 156 GLU A CB    1 
ATOM   1144 C  CG    . GLU A 1 156 ? 87.660  104.125 114.893 1.00 32.50 ? 156 GLU A CG    1 
ATOM   1145 C  CD    . GLU A 1 156 ? 86.677  104.870 115.775 1.00 32.50 ? 156 GLU A CD    1 
ATOM   1146 O  OE1   . GLU A 1 156 ? 86.884  106.078 116.021 1.00 32.50 ? 156 GLU A OE1   1 
ATOM   1147 O  OE2   . GLU A 1 156 ? 85.688  104.249 116.212 1.00 32.50 ? 156 GLU A OE2   1 
ATOM   1148 N  N     . LEU A 1 157 ? 88.189  106.202 110.796 1.00 28.93 ? 157 LEU A N     1 
ATOM   1149 C  CA    . LEU A 1 157 ? 88.677  107.189 109.835 1.00 28.93 ? 157 LEU A CA    1 
ATOM   1150 C  C     . LEU A 1 157 ? 87.590  107.883 109.034 1.00 28.93 ? 157 LEU A C     1 
ATOM   1151 O  O     . LEU A 1 157 ? 87.805  109.016 108.593 1.00 28.93 ? 157 LEU A O     1 
ATOM   1152 C  CB    . LEU A 1 157 ? 89.683  106.521 108.909 1.00 28.93 ? 157 LEU A CB    1 
ATOM   1153 C  CG    . LEU A 1 157 ? 91.054  106.513 109.573 1.00 28.93 ? 157 LEU A CG    1 
ATOM   1154 C  CD1   . LEU A 1 157 ? 91.782  105.306 109.203 1.00 28.93 ? 157 LEU A CD1   1 
ATOM   1155 C  CD2   . LEU A 1 157 ? 91.823  107.712 109.078 1.00 28.93 ? 157 LEU A CD2   1 
ATOM   1156 N  N     . LYS A 1 158 ? 86.421  107.271 108.862 1.00 27.93 ? 158 LYS A N     1 
ATOM   1157 C  CA    . LYS A 1 158 ? 85.286  108.043 108.377 1.00 27.93 ? 158 LYS A CA    1 
ATOM   1158 C  C     . LYS A 1 158 ? 84.894  109.124 109.373 1.00 27.93 ? 158 LYS A C     1 
ATOM   1159 O  O     . LYS A 1 158 ? 84.622  110.259 108.984 1.00 27.93 ? 158 LYS A O     1 
ATOM   1160 C  CB    . LYS A 1 158 ? 84.100  107.134 108.050 1.00 27.93 ? 158 LYS A CB    1 
ATOM   1161 C  CG    . LYS A 1 158 ? 83.062  107.857 107.207 1.00 27.93 ? 158 LYS A CG    1 
ATOM   1162 C  CD    . LYS A 1 158 ? 81.921  106.986 106.737 1.00 27.93 ? 158 LYS A CD    1 
ATOM   1163 C  CE    . LYS A 1 158 ? 81.076  106.452 107.875 1.00 27.93 ? 158 LYS A CE    1 
ATOM   1164 N  NZ    . LYS A 1 158 ? 79.896  105.705 107.352 1.00 27.93 ? 158 LYS A NZ    1 
ATOM   1165 N  N     . LYS A 1 159 ? 84.876  108.790 110.664 1.00 31.80 ? 159 LYS A N     1 
ATOM   1166 C  CA    . LYS A 1 159 ? 84.669  109.789 111.715 1.00 31.80 ? 159 LYS A CA    1 
ATOM   1167 C  C     . LYS A 1 159 ? 85.759  110.857 111.745 1.00 31.80 ? 159 LYS A C     1 
ATOM   1168 O  O     . LYS A 1 159 ? 85.474  112.017 112.027 1.00 31.80 ? 159 LYS A O     1 
ATOM   1169 C  CB    . LYS A 1 159 ? 84.594  109.087 113.069 1.00 31.80 ? 159 LYS A CB    1 
ATOM   1170 C  CG    . LYS A 1 159 ? 83.399  108.161 113.218 1.00 31.80 ? 159 LYS A CG    1 
ATOM   1171 C  CD    . LYS A 1 159 ? 83.616  107.115 114.316 1.00 31.80 ? 159 LYS A CD    1 
ATOM   1172 C  CE    . LYS A 1 159 ? 83.714  107.739 115.696 1.00 31.80 ? 159 LYS A CE    1 
ATOM   1173 N  NZ    . LYS A 1 159 ? 82.368  108.030 116.249 1.00 31.80 ? 159 LYS A NZ    1 
ATOM   1174 N  N     . ALA A 1 160 ? 86.999  110.499 111.431 1.00 31.01 ? 160 ALA A N     1 
ATOM   1175 C  CA    . ALA A 1 160 ? 88.066  111.491 111.296 1.00 31.01 ? 160 ALA A CA    1 
ATOM   1176 C  C     . ALA A 1 160 ? 87.867  112.423 110.103 1.00 31.01 ? 160 ALA A C     1 
ATOM   1177 O  O     . ALA A 1 160 ? 88.101  113.629 110.210 1.00 31.01 ? 160 ALA A O     1 
ATOM   1178 C  CB    . ALA A 1 160 ? 89.410  110.782 111.183 1.00 31.01 ? 160 ALA A CB    1 
ATOM   1179 N  N     . VAL A 1 161 ? 87.462  111.883 108.956 1.00 31.02 ? 161 VAL A N     1 
ATOM   1180 C  CA    . VAL A 1 161 ? 87.127  112.707 107.796 1.00 31.02 ? 161 VAL A CA    1 
ATOM   1181 C  C     . VAL A 1 161 ? 85.967  113.634 108.125 1.00 31.02 ? 161 VAL A C     1 
ATOM   1182 O  O     . VAL A 1 161 ? 85.994  114.834 107.827 1.00 31.02 ? 161 VAL A O     1 
ATOM   1183 C  CB    . VAL A 1 161 ? 86.805  111.807 106.588 1.00 31.02 ? 161 VAL A CB    1 
ATOM   1184 C  CG1   . VAL A 1 161 ? 86.140  112.584 105.474 1.00 31.02 ? 161 VAL A CG1   1 
ATOM   1185 C  CG2   . VAL A 1 161 ? 88.052  111.113 106.095 1.00 31.02 ? 161 VAL A CG2   1 
ATOM   1186 N  N     . ASP A 1 162 ? 84.919  113.070 108.719 1.00 35.73 ? 162 ASP A N     1 
ATOM   1187 C  CA    . ASP A 1 162 ? 83.774  113.819 109.216 1.00 35.73 ? 162 ASP A CA    1 
ATOM   1188 C  C     . ASP A 1 162 ? 84.171  114.959 110.147 1.00 35.73 ? 162 ASP A C     1 
ATOM   1189 O  O     . ASP A 1 162 ? 83.649  116.073 110.035 1.00 35.73 ? 162 ASP A O     1 
ATOM   1190 C  CB    . ASP A 1 162 ? 82.839  112.837 109.917 1.00 35.73 ? 162 ASP A CB    1 
ATOM   1191 C  CG    . ASP A 1 162 ? 81.714  113.514 110.645 1.00 35.73 ? 162 ASP A CG    1 
ATOM   1192 O  OD1   . ASP A 1 162 ? 81.198  114.537 110.145 1.00 35.73 ? 162 ASP A OD1   1 
ATOM   1193 O  OD2   . ASP A 1 162 ? 81.349  113.017 111.736 1.00 35.73 ? 162 ASP A OD2   1 
ATOM   1194 N  N     . LYS A 1 163 ? 85.081  114.699 111.083 1.00 36.23 ? 163 LYS A N     1 
ATOM   1195 C  CA    . LYS A 1 163 ? 85.596  115.761 111.942 1.00 36.23 ? 163 LYS A CA    1 
ATOM   1196 C  C     . LYS A 1 163 ? 86.359  116.827 111.158 1.00 36.23 ? 163 LYS A C     1 
ATOM   1197 O  O     . LYS A 1 163 ? 86.100  118.023 111.307 1.00 36.23 ? 163 LYS A O     1 
ATOM   1198 C  CB    . LYS A 1 163 ? 86.479  115.152 113.027 1.00 36.23 ? 163 LYS A CB    1 
ATOM   1199 C  CG    . LYS A 1 163 ? 86.847  116.121 114.135 1.00 36.23 ? 163 LYS A CG    1 
ATOM   1200 C  CD    . LYS A 1 163 ? 87.843  115.506 115.107 1.00 36.23 ? 163 LYS A CD    1 
ATOM   1201 C  CE    . LYS A 1 163 ? 88.220  116.499 116.186 1.00 36.23 ? 163 LYS A CE    1 
ATOM   1202 N  NZ    . LYS A 1 163 ? 89.370  116.066 117.027 1.00 36.23 ? 163 LYS A NZ    1 
ATOM   1203 N  N     . GLU A 1 164 ? 87.277  116.415 110.288 1.00 35.87 ? 164 GLU A N     1 
ATOM   1204 C  CA    . GLU A 1 164 ? 88.136  117.373 109.595 1.00 35.87 ? 164 GLU A CA    1 
ATOM   1205 C  C     . GLU A 1 164 ? 87.375  118.246 108.607 1.00 35.87 ? 164 GLU A C     1 
ATOM   1206 O  O     . GLU A 1 164 ? 87.774  119.389 108.358 1.00 35.87 ? 164 GLU A O     1 
ATOM   1207 C  CB    . GLU A 1 164 ? 89.257  116.624 108.885 1.00 35.87 ? 164 GLU A CB    1 
ATOM   1208 C  CG    . GLU A 1 164 ? 90.353  117.499 108.301 1.00 35.87 ? 164 GLU A CG    1 
ATOM   1209 C  CD    . GLU A 1 164 ? 91.028  118.416 109.314 1.00 35.87 ? 164 GLU A CD    1 
ATOM   1210 O  OE1   . GLU A 1 164 ? 91.259  117.994 110.465 1.00 35.87 ? 164 GLU A OE1   1 
ATOM   1211 O  OE2   . GLU A 1 164 ? 91.351  119.559 108.939 1.00 35.87 ? 164 GLU A OE2   1 
ATOM   1212 N  N     . LEU A 1 165 ? 86.293  117.734 108.035 1.00 35.04 ? 165 LEU A N     1 
ATOM   1213 C  CA    . LEU A 1 165 ? 85.461  118.505 107.120 1.00 35.04 ? 165 LEU A CA    1 
ATOM   1214 C  C     . LEU A 1 165 ? 84.881  119.787 107.723 1.00 35.04 ? 165 LEU A C     1 
ATOM   1215 O  O     . LEU A 1 165 ? 84.418  120.648 106.970 1.00 35.04 ? 165 LEU A O     1 
ATOM   1216 C  CB    . LEU A 1 165 ? 84.339  117.613 106.594 1.00 35.04 ? 165 LEU A CB    1 
ATOM   1217 C  CG    . LEU A 1 165 ? 84.710  116.611 105.496 1.00 35.04 ? 165 LEU A CG    1 
ATOM   1218 C  CD1   . LEU A 1 165 ? 83.611  115.618 105.319 1.00 35.04 ? 165 LEU A CD1   1 
ATOM   1219 C  CD2   . LEU A 1 165 ? 84.951  117.332 104.193 1.00 35.04 ? 165 LEU A CD2   1 
ATOM   1220 N  N     . GLU A 1 166 ? 84.894  119.945 109.048 1.00 41.20 ? 166 GLU A N     1 
ATOM   1221 C  CA    . GLU A 1 166 ? 84.561  121.232 109.657 1.00 41.20 ? 166 GLU A CA    1 
ATOM   1222 C  C     . GLU A 1 166 ? 85.490  122.366 109.227 1.00 41.20 ? 166 GLU A C     1 
ATOM   1223 O  O     . GLU A 1 166 ? 85.087  123.532 109.233 1.00 41.20 ? 166 GLU A O     1 
ATOM   1224 C  CB    . GLU A 1 166 ? 84.593  121.099 111.173 1.00 41.20 ? 166 GLU A CB    1 
ATOM   1225 C  CG    . GLU A 1 166 ? 83.619  120.082 111.725 1.00 41.20 ? 166 GLU A CG    1 
ATOM   1226 C  CD    . GLU A 1 166 ? 82.173  120.403 111.440 1.00 41.20 ? 166 GLU A CD    1 
ATOM   1227 O  OE1   . GLU A 1 166 ? 81.852  121.581 111.177 1.00 41.20 ? 166 GLU A OE1   1 
ATOM   1228 O  OE2   . GLU A 1 166 ? 81.348  119.470 111.480 1.00 41.20 ? 166 GLU A OE2   1 
ATOM   1229 N  N     . ASN A 1 167 ? 86.716  122.057 108.840 1.00 40.82 ? 167 ASN A N     1 
ATOM   1230 C  CA    . ASN A 1 167 ? 87.661  123.042 108.333 1.00 40.82 ? 167 ASN A CA    1 
ATOM   1231 C  C     . ASN A 1 167 ? 87.539  123.273 106.834 1.00 40.82 ? 167 ASN A C     1 
ATOM   1232 O  O     . ASN A 1 167 ? 88.414  123.917 106.250 1.00 40.82 ? 167 ASN A O     1 
ATOM   1233 C  CB    . ASN A 1 167 ? 89.087  122.625 108.697 1.00 40.82 ? 167 ASN A CB    1 
ATOM   1234 C  CG    . ASN A 1 167 ? 89.265  122.406 110.191 1.00 40.82 ? 167 ASN A CG    1 
ATOM   1235 O  OD1   . ASN A 1 167 ? 88.811  123.205 111.003 1.00 40.82 ? 167 ASN A OD1   1 
ATOM   1236 N  ND2   . ASN A 1 167 ? 89.894  121.303 110.558 1.00 40.82 ? 167 ASN A ND2   1 
ATOM   1237 N  N     . HIS A 1 168 ? 86.492  122.751 106.193 1.00 35.45 ? 168 HIS A N     1 
ATOM   1238 C  CA    . HIS A 1 168 ? 86.331  122.809 104.741 1.00 35.45 ? 168 HIS A CA    1 
ATOM   1239 C  C     . HIS A 1 168 ? 85.025  123.502 104.383 1.00 35.45 ? 168 HIS A C     1 
ATOM   1240 O  O     . HIS A 1 168 ? 83.969  122.857 104.322 1.00 35.45 ? 168 HIS A O     1 
ATOM   1241 C  CB    . HIS A 1 168 ? 86.364  121.400 104.170 1.00 35.45 ? 168 HIS A CB    1 
ATOM   1242 C  CG    . HIS A 1 168 ? 87.720  120.785 104.198 1.00 35.45 ? 168 HIS A CG    1 
ATOM   1243 N  ND1   . HIS A 1 168 ? 88.702  121.110 103.292 1.00 35.45 ? 168 HIS A ND1   1 
ATOM   1244 C  CD2   . HIS A 1 168 ? 88.274  119.903 105.058 1.00 35.45 ? 168 HIS A CD2   1 
ATOM   1245 C  CE1   . HIS A 1 168 ? 89.796  120.428 103.573 1.00 35.45 ? 168 HIS A CE1   1 
ATOM   1246 N  NE2   . HIS A 1 168 ? 89.563  119.690 104.643 1.00 35.45 ? 168 HIS A NE2   1 
ATOM   1247 N  N     . PRO A 1 169 ? 85.060  124.813 104.132 1.00 36.33 ? 169 PRO A N     1 
ATOM   1248 C  CA    . PRO A 1 169 ? 83.828  125.579 103.856 1.00 36.33 ? 169 PRO A CA    1 
ATOM   1249 C  C     . PRO A 1 169 ? 82.892  124.999 102.806 1.00 36.33 ? 169 PRO A C     1 
ATOM   1250 O  O     . PRO A 1 169 ? 81.674  125.051 102.994 1.00 36.33 ? 169 PRO A O     1 
ATOM   1251 C  CB    . PRO A 1 169 ? 84.378  126.935 103.395 1.00 36.33 ? 169 PRO A CB    1 
ATOM   1252 C  CG    . PRO A 1 169 ? 85.645  127.069 104.113 1.00 36.33 ? 169 PRO A CG    1 
ATOM   1253 C  CD    . PRO A 1 169 ? 86.239  125.687 104.191 1.00 36.33 ? 169 PRO A CD    1 
ATOM   1254 N  N     . VAL A 1 170 ? 83.416  124.448 101.709 1.00 34.47 ? 170 VAL A N     1 
ATOM   1255 C  CA    . VAL A 1 170 ? 82.570  123.883 100.661 1.00 34.47 ? 170 VAL A CA    1 
ATOM   1256 C  C     . VAL A 1 170 ? 81.712  122.722 101.148 1.00 34.47 ? 170 VAL A C     1 
ATOM   1257 O  O     . VAL A 1 170 ? 80.679  122.417 100.545 1.00 34.47 ? 170 VAL A O     1 
ATOM   1258 C  CB    . VAL A 1 170 ? 83.448  123.469 99.458  1.00 34.47 ? 170 VAL A CB    1 
ATOM   1259 C  CG1   . VAL A 1 170 ? 84.263  122.241 99.779  1.00 34.47 ? 170 VAL A CG1   1 
ATOM   1260 C  CG2   . VAL A 1 170 ? 82.603  123.245 98.215  1.00 34.47 ? 170 VAL A CG2   1 
ATOM   1261 N  N     . TYR A 1 171 ? 82.102  122.062 102.228 1.00 32.55 ? 171 TYR A N     1 
ATOM   1262 C  CA    . TYR A 1 171 ? 81.205  121.091 102.852 1.00 32.55 ? 171 TYR A CA    1 
ATOM   1263 C  C     . TYR A 1 171 ? 80.163  121.775 103.731 1.00 32.55 ? 171 TYR A C     1 
ATOM   1264 O  O     . TYR A 1 171 ? 78.964  121.747 103.438 1.00 32.55 ? 171 TYR A O     1 
ATOM   1265 C  CB    . TYR A 1 171 ? 82.026  120.074 103.640 1.00 32.55 ? 171 TYR A CB    1 
ATOM   1266 C  CG    . TYR A 1 171 ? 81.221  119.048 104.347 1.00 32.55 ? 171 TYR A CG    1 
ATOM   1267 C  CD1   . TYR A 1 171 ? 80.606  118.027 103.653 1.00 32.55 ? 171 TYR A CD1   1 
ATOM   1268 C  CD2   . TYR A 1 171 ? 81.110  119.064 105.712 1.00 32.55 ? 171 TYR A CD2   1 
ATOM   1269 C  CE1   . TYR A 1 171 ? 79.867  117.054 104.306 1.00 32.55 ? 171 TYR A CE1   1 
ATOM   1270 C  CE2   . TYR A 1 171 ? 80.391  118.103 106.379 1.00 32.55 ? 171 TYR A CE2   1 
ATOM   1271 C  CZ    . TYR A 1 171 ? 79.766  117.095 105.674 1.00 32.55 ? 171 TYR A CZ    1 
ATOM   1272 O  OH    . TYR A 1 171 ? 79.046  116.131 106.337 1.00 32.55 ? 171 TYR A OH    1 
ATOM   1273 N  N     . THR A 1 172 ? 80.618  122.405 104.810 1.00 37.50 ? 172 THR A N     1 
ATOM   1274 C  CA    . THR A 1 172 ? 79.718  122.947 105.820 1.00 37.50 ? 172 THR A CA    1 
ATOM   1275 C  C     . THR A 1 172 ? 78.765  123.986 105.246 1.00 37.50 ? 172 THR A C     1 
ATOM   1276 O  O     . THR A 1 172 ? 77.625  124.091 105.704 1.00 37.50 ? 172 THR A O     1 
ATOM   1277 C  CB    . THR A 1 172 ? 80.535  123.548 106.960 1.00 37.50 ? 172 THR A CB    1 
ATOM   1278 O  OG1   . THR A 1 172 ? 81.295  124.656 106.468 1.00 37.50 ? 172 THR A OG1   1 
ATOM   1279 C  CG2   . THR A 1 172 ? 81.495  122.503 107.506 1.00 37.50 ? 172 THR A CG2   1 
ATOM   1280 N  N     . GLN A 1 173 ? 79.198  124.756 104.253 1.00 40.76 ? 173 GLN A N     1 
ATOM   1281 C  CA    . GLN A 1 173 ? 78.318  125.734 103.627 1.00 40.76 ? 173 GLN A CA    1 
ATOM   1282 C  C     . GLN A 1 173 ? 77.463  125.189 102.488 1.00 40.76 ? 173 GLN A C     1 
ATOM   1283 O  O     . GLN A 1 173 ? 76.453  125.818 102.157 1.00 40.76 ? 173 GLN A O     1 
ATOM   1284 C  CB    . GLN A 1 173 ? 79.127  126.925 103.110 1.00 40.76 ? 173 GLN A CB    1 
ATOM   1285 C  CG    . GLN A 1 173 ? 79.959  127.607 104.175 1.00 40.76 ? 173 GLN A CG    1 
ATOM   1286 C  CD    . GLN A 1 173 ? 80.442  128.956 103.731 1.00 40.76 ? 173 GLN A CD    1 
ATOM   1287 O  OE1   . GLN A 1 173 ? 80.032  129.452 102.687 1.00 40.76 ? 173 GLN A OE1   1 
ATOM   1288 N  NE2   . GLN A 1 173 ? 81.307  129.576 104.528 1.00 40.76 ? 173 GLN A NE2   1 
ATOM   1289 N  N     . TRP A 1 174 ? 77.811  124.046 101.888 1.00 37.39 ? 174 TRP A N     1 
ATOM   1290 C  CA    . TRP A 1 174 ? 77.119  123.608 100.676 1.00 37.39 ? 174 TRP A CA    1 
ATOM   1291 C  C     . TRP A 1 174 ? 76.921  122.094 100.579 1.00 37.39 ? 174 TRP A C     1 
ATOM   1292 O  O     . TRP A 1 174 ? 75.782  121.626 100.593 1.00 37.39 ? 174 TRP A O     1 
ATOM   1293 C  CB    . TRP A 1 174 ? 77.834  124.145 99.430  1.00 37.39 ? 174 TRP A CB    1 
ATOM   1294 C  CG    . TRP A 1 174 ? 77.130  123.787 98.158  1.00 37.39 ? 174 TRP A CG    1 
ATOM   1295 C  CD1   . TRP A 1 174 ? 75.863  124.130 97.803  1.00 37.39 ? 174 TRP A CD1   1 
ATOM   1296 C  CD2   . TRP A 1 174 ? 77.680  123.089 97.036  1.00 37.39 ? 174 TRP A CD2   1 
ATOM   1297 N  NE1   . TRP A 1 174 ? 75.568  123.641 96.560  1.00 37.39 ? 174 TRP A NE1   1 
ATOM   1298 C  CE2   . TRP A 1 174 ? 76.672  123.001 96.065  1.00 37.39 ? 174 TRP A CE2   1 
ATOM   1299 C  CE3   . TRP A 1 174 ? 78.922  122.521 96.764  1.00 37.39 ? 174 TRP A CE3   1 
ATOM   1300 C  CZ2   . TRP A 1 174 ? 76.865  122.366 94.849  1.00 37.39 ? 174 TRP A CZ2   1 
ATOM   1301 C  CZ3   . TRP A 1 174 ? 79.111  121.895 95.552  1.00 37.39 ? 174 TRP A CZ3   1 
ATOM   1302 C  CH2   . TRP A 1 174 ? 78.087  121.819 94.613  1.00 37.39 ? 174 TRP A CH2   1 
ATOM   1303 N  N     . LEU A 1 175 ? 77.989  121.315 100.454 1.00 33.10 ? 175 LEU A N     1 
ATOM   1304 C  CA    . LEU A 1 175 ? 77.808  119.889 100.207 1.00 33.10 ? 175 LEU A CA    1 
ATOM   1305 C  C     . LEU A 1 175 ? 77.099  119.177 101.344 1.00 33.10 ? 175 LEU A C     1 
ATOM   1306 O  O     . LEU A 1 175 ? 76.517  118.117 101.118 1.00 33.10 ? 175 LEU A O     1 
ATOM   1307 C  CB    . LEU A 1 175 ? 79.147  119.208 99.941  1.00 33.10 ? 175 LEU A CB    1 
ATOM   1308 C  CG    . LEU A 1 175 ? 79.874  119.715 98.701  1.00 33.10 ? 175 LEU A CG    1 
ATOM   1309 C  CD1   . LEU A 1 175 ? 81.315  119.304 98.762  1.00 33.10 ? 175 LEU A CD1   1 
ATOM   1310 C  CD2   . LEU A 1 175 ? 79.217  119.157 97.465  1.00 33.10 ? 175 LEU A CD2   1 
ATOM   1311 N  N     . GLN A 1 176 ? 77.134  119.726 102.555 1.00 34.84 ? 176 GLN A N     1 
ATOM   1312 C  CA    . GLN A 1 176 ? 76.390  119.138 103.665 1.00 34.84 ? 176 GLN A CA    1 
ATOM   1313 C  C     . GLN A 1 176 ? 74.890  119.105 103.409 1.00 34.84 ? 176 GLN A C     1 
ATOM   1314 O  O     . GLN A 1 176 ? 74.215  118.147 103.798 1.00 34.84 ? 176 GLN A O     1 
ATOM   1315 C  CB    . GLN A 1 176 ? 76.692  119.927 104.938 1.00 34.84 ? 176 GLN A CB    1 
ATOM   1316 C  CG    . GLN A 1 176 ? 75.992  119.445 106.181 1.00 34.84 ? 176 GLN A CG    1 
ATOM   1317 C  CD    . GLN A 1 176 ? 76.650  119.972 107.427 1.00 34.84 ? 176 GLN A CD    1 
ATOM   1318 O  OE1   . GLN A 1 176 ? 77.004  119.211 108.324 1.00 34.84 ? 176 GLN A OE1   1 
ATOM   1319 N  NE2   . GLN A 1 176 ? 76.831  121.281 107.489 1.00 34.84 ? 176 GLN A NE2   1 
ATOM   1320 N  N     . HIS A 1 177 ? 74.365  120.110 102.717 1.00 37.97 ? 177 HIS A N     1 
ATOM   1321 C  CA    . HIS A 1 177 ? 72.932  120.313 102.576 1.00 37.97 ? 177 HIS A CA    1 
ATOM   1322 C  C     . HIS A 1 177 ? 72.313  119.558 101.408 1.00 37.97 ? 177 HIS A C     1 
ATOM   1323 O  O     . HIS A 1 177 ? 71.091  119.385 101.378 1.00 37.97 ? 177 HIS A O     1 
ATOM   1324 C  CB    . HIS A 1 177 ? 72.677  121.809 102.441 1.00 37.97 ? 177 HIS A CB    1 
ATOM   1325 C  CG    . HIS A 1 177 ? 73.257  122.601 103.571 1.00 37.97 ? 177 HIS A CG    1 
ATOM   1326 N  ND1   . HIS A 1 177 ? 72.781  122.520 104.861 1.00 37.97 ? 177 HIS A ND1   1 
ATOM   1327 C  CD2   . HIS A 1 177 ? 74.302  123.458 103.609 1.00 37.97 ? 177 HIS A CD2   1 
ATOM   1328 C  CE1   . HIS A 1 177 ? 73.501  123.304 105.642 1.00 37.97 ? 177 HIS A CE1   1 
ATOM   1329 N  NE2   . HIS A 1 177 ? 74.429  123.885 104.908 1.00 37.97 ? 177 HIS A NE2   1 
ATOM   1330 N  N     . ILE A 1 178 ? 73.119  119.110 100.453 1.00 30.71 ? 178 ILE A N     1 
ATOM   1331 C  CA    . ILE A 1 178 ? 72.624  118.319 99.334  1.00 30.71 ? 178 ILE A CA    1 
ATOM   1332 C  C     . ILE A 1 178 ? 72.248  116.929 99.828  1.00 30.71 ? 178 ILE A C     1 
ATOM   1333 O  O     . ILE A 1 178 ? 73.077  116.212 100.395 1.00 30.71 ? 178 ILE A O     1 
ATOM   1334 C  CB    . ILE A 1 178 ? 73.669  118.262 98.219  1.00 30.71 ? 178 ILE A CB    1 
ATOM   1335 C  CG1   . ILE A 1 178 ? 73.862  119.658 97.632  1.00 30.71 ? 178 ILE A CG1   1 
ATOM   1336 C  CG2   . ILE A 1 178 ? 73.259  117.276 97.172  1.00 30.71 ? 178 ILE A CG2   1 
ATOM   1337 C  CD1   . ILE A 1 178 ? 74.985  119.782 96.646  1.00 30.71 ? 178 ILE A CD1   1 
ATOM   1338 N  N     . LYS A 1 179 ? 70.976  116.563 99.668  1.00 27.78 ? 179 LYS A N     1 
ATOM   1339 C  CA    . LYS A 1 179 ? 70.530  115.236 100.073 1.00 27.78 ? 179 LYS A CA    1 
ATOM   1340 C  C     . LYS A 1 179 ? 71.289  114.159 99.310  1.00 27.78 ? 179 LYS A C     1 
ATOM   1341 O  O     . LYS A 1 179 ? 71.406  114.213 98.086  1.00 27.78 ? 179 LYS A O     1 
ATOM   1342 C  CB    . LYS A 1 179 ? 69.026  115.060 99.849  1.00 27.78 ? 179 LYS A CB    1 
ATOM   1343 C  CG    . LYS A 1 179 ? 68.573  113.689 100.321 1.00 27.78 ? 179 LYS A CG    1 
ATOM   1344 C  CD    . LYS A 1 179 ? 67.082  113.436 100.311 1.00 27.78 ? 179 LYS A CD    1 
ATOM   1345 C  CE    . LYS A 1 179 ? 66.836  111.965 100.642 1.00 27.78 ? 179 LYS A CE    1 
ATOM   1346 N  NZ    . LYS A 1 179 ? 65.443  111.605 101.019 1.00 27.78 ? 179 LYS A NZ    1 
ATOM   1347 N  N     . GLY A 1 180 ? 71.824  113.192 100.037 1.00 25.26 ? 180 GLY A N     1 
ATOM   1348 C  CA    . GLY A 1 180 ? 72.622  112.153 99.438  1.00 25.26 ? 180 GLY A CA    1 
ATOM   1349 C  C     . GLY A 1 180 ? 74.099  112.452 99.349  1.00 25.26 ? 180 GLY A C     1 
ATOM   1350 O  O     . GLY A 1 180 ? 74.850  111.610 98.851  1.00 25.26 ? 180 GLY A O     1 
ATOM   1351 N  N     . ILE A 1 181 ? 74.547  113.607 99.833  1.00 25.91 ? 181 ILE A N     1 
ATOM   1352 C  CA    . ILE A 1 181 ? 75.962  113.872 100.058 1.00 25.91 ? 181 ILE A CA    1 
ATOM   1353 C  C     . ILE A 1 181 ? 76.258  113.851 101.548 1.00 25.91 ? 181 ILE A C     1 
ATOM   1354 O  O     . ILE A 1 181 ? 75.528  114.451 102.347 1.00 25.91 ? 181 ILE A O     1 
ATOM   1355 C  CB    . ILE A 1 181 ? 76.411  115.192 99.416  1.00 25.91 ? 181 ILE A CB    1 
ATOM   1356 C  CG1   . ILE A 1 181 ? 76.253  115.095 97.908  1.00 25.91 ? 181 ILE A CG1   1 
ATOM   1357 C  CG2   . ILE A 1 181 ? 77.831  115.508 99.792  1.00 25.91 ? 181 ILE A CG2   1 
ATOM   1358 C  CD1   . ILE A 1 181 ? 76.792  116.289 97.153  1.00 25.91 ? 181 ILE A CD1   1 
ATOM   1359 N  N     . GLY A 1 182 ? 77.324  113.141 101.910 1.00 26.25 ? 182 GLY A N     1 
ATOM   1360 C  CA    . GLY A 1 182 ? 77.848  113.083 103.251 1.00 26.25 ? 182 GLY A CA    1 
ATOM   1361 C  C     . GLY A 1 182 ? 79.362  113.203 103.272 1.00 26.25 ? 182 GLY A C     1 
ATOM   1362 O  O     . GLY A 1 182 ? 79.971  113.808 102.388 1.00 26.25 ? 182 GLY A O     1 
ATOM   1363 N  N     . PRO A 1 183 ? 79.986  112.704 104.340 1.00 27.73 ? 183 PRO A N     1 
ATOM   1364 C  CA    . PRO A 1 183 ? 81.430  112.908 104.526 1.00 27.73 ? 183 PRO A CA    1 
ATOM   1365 C  C     . PRO A 1 183 ? 82.332  112.259 103.485 1.00 27.73 ? 183 PRO A C     1 
ATOM   1366 O  O     . PRO A 1 183 ? 83.397  112.808 103.207 1.00 27.73 ? 183 PRO A O     1 
ATOM   1367 C  CB    . PRO A 1 183 ? 81.685  112.304 105.910 1.00 27.73 ? 183 PRO A CB    1 
ATOM   1368 C  CG    . PRO A 1 183 ? 80.406  112.372 106.586 1.00 27.73 ? 183 PRO A CG    1 
ATOM   1369 C  CD    . PRO A 1 183 ? 79.378  112.108 105.531 1.00 27.73 ? 183 PRO A CD    1 
ATOM   1370 N  N     . VAL A 1 184 ? 81.989  111.089 102.949 1.00 21.77 ? 184 VAL A N     1 
ATOM   1371 C  CA    . VAL A 1 184 ? 82.904  110.375 102.054 1.00 21.77 ? 184 VAL A CA    1 
ATOM   1372 C  C     . VAL A 1 184 ? 82.875  110.922 100.633 1.00 21.77 ? 184 VAL A C     1 
ATOM   1373 O  O     . VAL A 1 184 ? 83.928  111.117 100.015 1.00 21.77 ? 184 VAL A O     1 
ATOM   1374 C  CB    . VAL A 1 184 ? 82.592  108.877 102.069 1.00 21.77 ? 184 VAL A CB    1 
ATOM   1375 C  CG1   . VAL A 1 184 ? 83.437  108.168 101.051 1.00 21.77 ? 184 VAL A CG1   1 
ATOM   1376 C  CG2   . VAL A 1 184 ? 82.840  108.333 103.435 1.00 21.77 ? 184 VAL A CG2   1 
ATOM   1377 N  N     . VAL A 1 185 ? 81.684  111.197 100.102 1.00 20.68 ? 185 VAL A N     1 
ATOM   1378 C  CA    . VAL A 1 185 ? 81.571  111.941 98.852  1.00 20.68 ? 185 VAL A CA    1 
ATOM   1379 C  C     . VAL A 1 185 ? 82.376  113.226 98.920  1.00 20.68 ? 185 VAL A C     1 
ATOM   1380 O  O     . VAL A 1 185 ? 83.167  113.529 98.022  1.00 20.68 ? 185 VAL A O     1 
ATOM   1381 C  CB    . VAL A 1 185 ? 80.094  112.221 98.523  1.00 20.68 ? 185 VAL A CB    1 
ATOM   1382 C  CG1   . VAL A 1 185 ? 79.973  113.384 97.550  1.00 20.68 ? 185 VAL A CG1   1 
ATOM   1383 C  CG2   . VAL A 1 185 ? 79.456  111.014 97.920  1.00 20.68 ? 185 VAL A CG2   1 
ATOM   1384 N  N     . ALA A 1 186 ? 82.193  114.000 99.985  1.00 22.23 ? 186 ALA A N     1 
ATOM   1385 C  CA    . ALA A 1 186 ? 82.846  115.299 100.057 1.00 22.23 ? 186 ALA A CA    1 
ATOM   1386 C  C     . ALA A 1 186 ? 84.334  115.155 100.329 1.00 22.23 ? 186 ALA A C     1 
ATOM   1387 O  O     . ALA A 1 186 ? 85.144  115.888 99.761  1.00 22.23 ? 186 ALA A O     1 
ATOM   1388 C  CB    . ALA A 1 186 ? 82.173  116.162 101.114 1.00 22.23 ? 186 ALA A CB    1 
ATOM   1389 N  N     . GLY A 1 187 ? 84.714  114.214 101.182 1.00 24.30 ? 187 GLY A N     1 
ATOM   1390 C  CA    . GLY A 1 187 ? 86.122  113.970 101.422 1.00 24.30 ? 187 GLY A CA    1 
ATOM   1391 C  C     . GLY A 1 187 ? 86.876  113.602 100.161 1.00 24.30 ? 187 GLY A C     1 
ATOM   1392 O  O     . GLY A 1 187 ? 87.934  114.169 99.870  1.00 24.30 ? 187 GLY A O     1 
ATOM   1393 N  N     . GLY A 1 188 ? 86.283  112.739 99.338  1.00 21.01 ? 188 GLY A N     1 
ATOM   1394 C  CA    . GLY A 1 188 ? 86.901  112.392 98.072  1.00 21.01 ? 188 GLY A CA    1 
ATOM   1395 C  C     . GLY A 1 188 ? 86.886  113.517 97.066  1.00 21.01 ? 188 GLY A C     1 
ATOM   1396 O  O     . GLY A 1 188 ? 87.903  113.824 96.461  1.00 21.01 ? 188 GLY A O     1 
ATOM   1397 N  N     . LEU A 1 189 ? 85.749  114.158 96.886  1.00 22.92 ? 189 LEU A N     1 
ATOM   1398 C  CA    . LEU A 1 189 ? 85.669  115.231 95.909  1.00 22.92 ? 189 LEU A CA    1 
ATOM   1399 C  C     . LEU A 1 189 ? 86.657  116.357 96.226  1.00 22.92 ? 189 LEU A C     1 
ATOM   1400 O  O     . LEU A 1 189 ? 87.451  116.774 95.362  1.00 22.92 ? 189 LEU A O     1 
ATOM   1401 C  CB    . LEU A 1 189 ? 84.231  115.730 95.894  1.00 22.92 ? 189 LEU A CB    1 
ATOM   1402 C  CG    . LEU A 1 189 ? 83.756  116.799 94.948  1.00 22.92 ? 189 LEU A CG    1 
ATOM   1403 C  CD1   . LEU A 1 189 ? 83.708  116.212 93.573  1.00 22.92 ? 189 LEU A CD1   1 
ATOM   1404 C  CD2   . LEU A 1 189 ? 82.397  117.215 95.431  1.00 22.92 ? 189 LEU A CD2   1 
ATOM   1405 N  N     . ILE A 1 190 ? 86.720  116.764 97.494  1.00 23.57 ? 190 ILE A N     1 
ATOM   1406 C  CA    . ILE A 1 190 ? 87.689  117.769 97.913  1.00 23.57 ? 190 ILE A CA    1 
ATOM   1407 C  C     . ILE A 1 190 ? 89.110  117.280 97.685  1.00 23.57 ? 190 ILE A C     1 
ATOM   1408 O  O     . ILE A 1 190 ? 89.865  117.895 96.930  1.00 23.57 ? 190 ILE A O     1 
ATOM   1409 C  CB    . ILE A 1 190 ? 87.463  118.173 99.380  1.00 23.57 ? 190 ILE A CB    1 
ATOM   1410 C  CG1   . ILE A 1 190 ? 86.154  118.948 99.535  1.00 23.57 ? 190 ILE A CG1   1 
ATOM   1411 C  CG2   . ILE A 1 190 ? 88.622  118.997 99.882  1.00 23.57 ? 190 ILE A CG2   1 
ATOM   1412 C  CD1   . ILE A 1 190 ? 85.667  119.009 100.944 1.00 23.57 ? 190 ILE A CD1   1 
ATOM   1413 N  N     . SER A 1 191 ? 89.496  116.156 98.297  1.00 22.59 ? 191 SER A N     1 
ATOM   1414 C  CA    . SER A 1 191 ? 90.909  115.804 98.253  1.00 22.59 ? 191 SER A CA    1 
ATOM   1415 C  C     . SER A 1 191 ? 91.380  115.399 96.858  1.00 22.59 ? 191 SER A C     1 
ATOM   1416 O  O     . SER A 1 191 ? 92.527  115.677 96.501  1.00 22.59 ? 191 SER A O     1 
ATOM   1417 C  CB    . SER A 1 191 ? 91.207  114.681 99.240  1.00 22.59 ? 191 SER A CB    1 
ATOM   1418 O  OG    . SER A 1 191 ? 90.571  113.489 98.870  1.00 22.59 ? 191 SER A OG    1 
ATOM   1419 N  N     . LEU A 1 192 ? 90.527  114.771 96.046  1.00 21.76 ? 192 LEU A N     1 
ATOM   1420 C  CA    . LEU A 1 192 ? 90.912  114.393 94.691  1.00 21.76 ? 192 LEU A CA    1 
ATOM   1421 C  C     . LEU A 1 192 ? 91.059  115.598 93.778  1.00 21.76 ? 192 LEU A C     1 
ATOM   1422 O  O     . LEU A 1 192 ? 91.909  115.591 92.887  1.00 21.76 ? 192 LEU A O     1 
ATOM   1423 C  CB    . LEU A 1 192 ? 89.900  113.417 94.111  1.00 21.76 ? 192 LEU A CB    1 
ATOM   1424 C  CG    . LEU A 1 192 ? 89.887  112.024 94.736  1.00 21.76 ? 192 LEU A CG    1 
ATOM   1425 C  CD1   . LEU A 1 192 ? 88.675  111.264 94.288  1.00 21.76 ? 192 LEU A CD1   1 
ATOM   1426 C  CD2   . LEU A 1 192 ? 91.130  111.287 94.359  1.00 21.76 ? 192 LEU A CD2   1 
ATOM   1427 N  N     . ILE A 1 193 ? 90.242  116.630 93.950  1.00 24.93 ? 193 ILE A N     1 
ATOM   1428 C  CA    . ILE A 1 193 ? 90.370  117.785 93.070  1.00 24.93 ? 193 ILE A CA    1 
ATOM   1429 C  C     . ILE A 1 193 ? 91.379  118.792 93.617  1.00 24.93 ? 193 ILE A C     1 
ATOM   1430 O  O     . ILE A 1 193 ? 92.281  119.234 92.906  1.00 24.93 ? 193 ILE A O     1 
ATOM   1431 C  CB    . ILE A 1 193 ? 88.984  118.418 92.864  1.00 24.93 ? 193 ILE A CB    1 
ATOM   1432 C  CG1   . ILE A 1 193 ? 88.038  117.368 92.286  1.00 24.93 ? 193 ILE A CG1   1 
ATOM   1433 C  CG2   . ILE A 1 193 ? 89.075  119.604 91.932  1.00 24.93 ? 193 ILE A CG2   1 
ATOM   1434 C  CD1   . ILE A 1 193 ? 86.615  117.797 92.301  1.00 24.93 ? 193 ILE A CD1   1 
ATOM   1435 N  N     . GLY A 1 194 ? 91.275  119.130 94.899  1.00 31.04 ? 194 GLY A N     1 
ATOM   1436 C  CA    . GLY A 1 194 ? 92.209  120.031 95.543  1.00 31.04 ? 194 GLY A CA    1 
ATOM   1437 C  C     . GLY A 1 194 ? 91.985  121.505 95.245  1.00 31.04 ? 194 GLY A C     1 
ATOM   1438 O  O     . GLY A 1 194 ? 90.875  121.943 94.948  1.00 31.04 ? 194 GLY A O     1 
ATOM   1439 N  N     . ASP A 1 195 ? 93.064  122.275 95.333  1.00 43.32 ? 195 ASP A N     1 
ATOM   1440 C  CA    . ASP A 1 195 ? 92.956  123.723 95.216  1.00 43.32 ? 195 ASP A CA    1 
ATOM   1441 C  C     . ASP A 1 195 ? 92.383  124.136 93.863  1.00 43.32 ? 195 ASP A C     1 
ATOM   1442 O  O     . ASP A 1 195 ? 92.878  123.730 92.810  1.00 43.32 ? 195 ASP A O     1 
ATOM   1443 C  CB    . ASP A 1 195 ? 94.324  124.360 95.441  1.00 43.32 ? 195 ASP A CB    1 
ATOM   1444 C  CG    . ASP A 1 195 ? 94.879  124.089 96.835  1.00 43.32 ? 195 ASP A CG    1 
ATOM   1445 O  OD1   . ASP A 1 195 ? 94.080  123.912 97.781  1.00 43.32 ? 195 ASP A OD1   1 
ATOM   1446 O  OD2   . ASP A 1 195 ? 96.118  124.091 96.994  1.00 43.32 ? 195 ASP A OD2   1 
ATOM   1447 N  N     . ILE A 1 196 ? 91.313  124.936 93.898  1.00 43.56 ? 196 ILE A N     1 
ATOM   1448 C  CA    . ILE A 1 196 ? 90.557  125.234 92.683  1.00 43.56 ? 196 ILE A CA    1 
ATOM   1449 C  C     . ILE A 1 196 ? 91.125  126.394 91.872  1.00 43.56 ? 196 ILE A C     1 
ATOM   1450 O  O     . ILE A 1 196 ? 90.526  126.786 90.861  1.00 43.56 ? 196 ILE A O     1 
ATOM   1451 C  CB    . ILE A 1 196 ? 89.079  125.430 93.072  1.00 43.56 ? 196 ILE A CB    1 
ATOM   1452 C  CG1   . ILE A 1 196 ? 88.174  125.057 91.904  1.00 43.56 ? 196 ILE A CG1   1 
ATOM   1453 C  CG2   . ILE A 1 196 ? 88.816  126.841 93.535  1.00 43.56 ? 196 ILE A CG2   1 
ATOM   1454 C  CD1   . ILE A 1 196 ? 87.930  123.578 91.770  1.00 43.56 ? 196 ILE A CD1   1 
ATOM   1455 N  N     . ASP A 1 197 ? 92.259  126.967 92.271  1.00 47.64 ? 197 ASP A N     1 
ATOM   1456 C  CA    . ASP A 1 197 ? 92.999  127.816 91.345  1.00 47.64 ? 197 ASP A CA    1 
ATOM   1457 C  C     . ASP A 1 197 ? 93.845  127.013 90.364  1.00 47.64 ? 197 ASP A C     1 
ATOM   1458 O  O     . ASP A 1 197 ? 94.410  127.602 89.437  1.00 47.64 ? 197 ASP A O     1 
ATOM   1459 C  CB    . ASP A 1 197 ? 93.854  128.851 92.090  1.00 47.64 ? 197 ASP A CB    1 
ATOM   1460 C  CG    . ASP A 1 197 ? 94.995  128.243 92.857  1.00 47.64 ? 197 ASP A CG    1 
ATOM   1461 O  OD1   . ASP A 1 197 ? 94.902  127.057 93.250  1.00 47.64 ? 197 ASP A OD1   1 
ATOM   1462 O  OD2   . ASP A 1 197 ? 95.997  128.965 93.066  1.00 47.64 ? 197 ASP A OD2   1 
ATOM   1463 N  N     . ARG A 1 198 ? 93.954  125.696 90.552  1.00 35.08 ? 198 ARG A N     1 
ATOM   1464 C  CA    . ARG A 1 198 ? 94.594  124.805 89.591  1.00 35.08 ? 198 ARG A CA    1 
ATOM   1465 C  C     . ARG A 1 198 ? 93.817  124.649 88.288  1.00 35.08 ? 198 ARG A C     1 
ATOM   1466 O  O     . ARG A 1 198 ? 94.371  124.111 87.326  1.00 35.08 ? 198 ARG A O     1 
ATOM   1467 C  CB    . ARG A 1 198 ? 94.808  123.428 90.217  1.00 35.08 ? 198 ARG A CB    1 
ATOM   1468 C  CG    . ARG A 1 198 ? 95.755  123.435 91.385  1.00 35.08 ? 198 ARG A CG    1 
ATOM   1469 C  CD    . ARG A 1 198 ? 96.399  122.089 91.617  1.00 35.08 ? 198 ARG A CD    1 
ATOM   1470 N  NE    . ARG A 1 198 ? 95.428  121.012 91.735  1.00 35.08 ? 198 ARG A NE    1 
ATOM   1471 C  CZ    . ARG A 1 198 ? 95.634  119.770 91.326  1.00 35.08 ? 198 ARG A CZ    1 
ATOM   1472 N  NH1   . ARG A 1 198 ? 96.754  119.419 90.724  1.00 35.08 ? 198 ARG A NH1   1 
ATOM   1473 N  NH2   . ARG A 1 198 ? 94.692  118.860 91.526  1.00 35.08 ? 198 ARG A NH2   1 
ATOM   1474 N  N     . PHE A 1 199 ? 92.556  125.068 88.229  1.00 31.60 ? 199 PHE A N     1 
ATOM   1475 C  CA    . PHE A 1 199 ? 91.700  124.853 87.063  1.00 31.60 ? 199 PHE A CA    1 
ATOM   1476 C  C     . PHE A 1 199 ? 91.075  126.191 86.668  1.00 31.60 ? 199 PHE A C     1 
ATOM   1477 O  O     . PHE A 1 199 ? 90.132  126.646 87.316  1.00 31.60 ? 199 PHE A O     1 
ATOM   1478 C  CB    . PHE A 1 199 ? 90.631  123.811 87.385  1.00 31.60 ? 199 PHE A CB    1 
ATOM   1479 C  CG    . PHE A 1 199 ? 91.179  122.512 87.949  1.00 31.60 ? 199 PHE A CG    1 
ATOM   1480 C  CD1   . PHE A 1 199 ? 91.775  121.574 87.135  1.00 31.60 ? 199 PHE A CD1   1 
ATOM   1481 C  CD2   . PHE A 1 199 ? 91.097  122.244 89.295  1.00 31.60 ? 199 PHE A CD2   1 
ATOM   1482 C  CE1   . PHE A 1 199 ? 92.273  120.403 87.651  1.00 31.60 ? 199 PHE A CE1   1 
ATOM   1483 C  CE2   . PHE A 1 199 ? 91.597  121.077 89.809  1.00 31.60 ? 199 PHE A CE2   1 
ATOM   1484 C  CZ    . PHE A 1 199 ? 92.187  120.156 88.982  1.00 31.60 ? 199 PHE A CZ    1 
ATOM   1485 N  N     . ASP A 1 200 ? 91.608  126.855 85.638  1.00 36.76 ? 200 ASP A N     1 
ATOM   1486 C  CA    . ASP A 1 200 ? 91.102  128.181 85.286  1.00 36.76 ? 200 ASP A CA    1 
ATOM   1487 C  C     . ASP A 1 200 ? 89.803  128.160 84.488  1.00 36.76 ? 200 ASP A C     1 
ATOM   1488 O  O     . ASP A 1 200 ? 89.232  129.226 84.249  1.00 36.76 ? 200 ASP A O     1 
ATOM   1489 C  CB    . ASP A 1 200 ? 92.160  128.998 84.535  1.00 36.76 ? 200 ASP A CB    1 
ATOM   1490 C  CG    . ASP A 1 200 ? 92.575  128.374 83.222  1.00 36.76 ? 200 ASP A CG    1 
ATOM   1491 O  OD1   . ASP A 1 200 ? 93.136  127.261 83.257  1.00 36.76 ? 200 ASP A OD1   1 
ATOM   1492 O  OD2   . ASP A 1 200 ? 92.354  128.998 82.162  1.00 36.76 ? 200 ASP A OD2   1 
ATOM   1493 N  N     . SER A 1 201 ? 89.322  126.996 84.074  1.00 30.68 ? 201 SER A N     1 
ATOM   1494 C  CA    . SER A 1 201 ? 88.029  126.865 83.424  1.00 30.68 ? 201 SER A CA    1 
ATOM   1495 C  C     . SER A 1 201 ? 87.374  125.585 83.923  1.00 30.68 ? 201 SER A C     1 
ATOM   1496 O  O     . SER A 1 201 ? 88.043  124.695 84.446  1.00 30.68 ? 201 SER A O     1 
ATOM   1497 C  CB    . SER A 1 201 ? 88.154  126.855 81.903  1.00 30.68 ? 201 SER A CB    1 
ATOM   1498 O  OG    . SER A 1 201 ? 88.376  125.544 81.424  1.00 30.68 ? 201 SER A OG    1 
ATOM   1499 N  N     . VAL A 1 202 ? 86.051  125.506 83.778  1.00 27.97 ? 202 VAL A N     1 
ATOM   1500 C  CA    . VAL A 1 202 ? 85.358  124.255 84.066  1.00 27.97 ? 202 VAL A CA    1 
ATOM   1501 C  C     . VAL A 1 202 ? 85.877  123.133 83.179  1.00 27.97 ? 202 VAL A C     1 
ATOM   1502 O  O     . VAL A 1 202 ? 86.014  121.988 83.621  1.00 27.97 ? 202 VAL A O     1 
ATOM   1503 C  CB    . VAL A 1 202 ? 83.840  124.428 83.885  1.00 27.97 ? 202 VAL A CB    1 
ATOM   1504 C  CG1   . VAL A 1 202 ? 83.143  123.106 84.079  1.00 27.97 ? 202 VAL A CG1   1 
ATOM   1505 C  CG2   . VAL A 1 202 ? 83.296  125.449 84.834  1.00 27.97 ? 202 VAL A CG2   1 
ATOM   1506 N  N     . SER A 1 203 ? 86.192  123.447 81.923  1.00 25.58 ? 203 SER A N     1 
ATOM   1507 C  CA    . SER A 1 203 ? 86.657  122.435 80.983  1.00 25.58 ? 203 SER A CA    1 
ATOM   1508 C  C     . SER A 1 203 ? 88.048  121.908 81.302  1.00 25.58 ? 203 SER A C     1 
ATOM   1509 O  O     . SER A 1 203 ? 88.334  120.744 81.016  1.00 25.58 ? 203 SER A O     1 
ATOM   1510 C  CB    . SER A 1 203 ? 86.607  122.995 79.575  1.00 25.58 ? 203 SER A CB    1 
ATOM   1511 O  OG    . SER A 1 203 ? 85.300  123.429 79.284  1.00 25.58 ? 203 SER A OG    1 
ATOM   1512 N  N     . LYS A 1 204 ? 88.904  122.710 81.941  1.00 26.03 ? 204 LYS A N     1 
ATOM   1513 C  CA    . LYS A 1 204 ? 90.131  122.163 82.513  1.00 26.03 ? 204 LYS A CA    1 
ATOM   1514 C  C     . LYS A 1 204 ? 89.838  121.099 83.557  1.00 26.03 ? 204 LYS A C     1 
ATOM   1515 O  O     . LYS A 1 204 ? 90.503  120.063 83.596  1.00 26.03 ? 204 LYS A O     1 
ATOM   1516 C  CB    . LYS A 1 204 ? 90.965  123.269 83.150  1.00 26.03 ? 204 LYS A CB    1 
ATOM   1517 C  CG    . LYS A 1 204 ? 91.467  124.370 82.234  1.00 26.03 ? 204 LYS A CG    1 
ATOM   1518 C  CD    . LYS A 1 204 ? 92.130  123.834 80.988  1.00 26.03 ? 204 LYS A CD    1 
ATOM   1519 C  CE    . LYS A 1 204 ? 92.576  124.974 80.093  1.00 26.03 ? 204 LYS A CE    1 
ATOM   1520 N  NZ    . LYS A 1 204 ? 93.632  125.763 80.758  1.00 26.03 ? 204 LYS A NZ    1 
ATOM   1521 N  N     . LEU A 1 205 ? 88.853  121.338 84.413  1.00 24.05 ? 205 LEU A N     1 
ATOM   1522 C  CA    . LEU A 1 205 ? 88.474  120.344 85.406  1.00 24.05 ? 205 LEU A CA    1 
ATOM   1523 C  C     . LEU A 1 205 ? 87.850  119.103 84.780  1.00 24.05 ? 205 LEU A C     1 
ATOM   1524 O  O     . LEU A 1 205 ? 88.165  117.984 85.197  1.00 24.05 ? 205 LEU A O     1 
ATOM   1525 C  CB    . LEU A 1 205 ? 87.547  120.981 86.433  1.00 24.05 ? 205 LEU A CB    1 
ATOM   1526 C  CG    . LEU A 1 205 ? 86.905  120.130 87.519  1.00 24.05 ? 205 LEU A CG    1 
ATOM   1527 C  CD1   . LEU A 1 205 ? 87.924  119.449 88.403  1.00 24.05 ? 205 LEU A CD1   1 
ATOM   1528 C  CD2   . LEU A 1 205 ? 86.026  121.030 88.353  1.00 24.05 ? 205 LEU A CD2   1 
ATOM   1529 N  N     . TRP A 1 206 ? 86.965  119.259 83.789  1.00 24.77 ? 206 TRP A N     1 
ATOM   1530 C  CA    . TRP A 1 206 ? 86.450  118.079 83.089  1.00 24.77 ? 206 TRP A CA    1 
ATOM   1531 C  C     . TRP A 1 206 ? 87.557  117.294 82.399  1.00 24.77 ? 206 TRP A C     1 
ATOM   1532 O  O     . TRP A 1 206 ? 87.595  116.063 82.483  1.00 24.77 ? 206 TRP A O     1 
ATOM   1533 C  CB    . TRP A 1 206 ? 85.378  118.459 82.062  1.00 24.77 ? 206 TRP A CB    1 
ATOM   1534 C  CG    . TRP A 1 206 ? 84.062  118.923 82.607  1.00 24.77 ? 206 TRP A CG    1 
ATOM   1535 C  CD1   . TRP A 1 206 ? 83.551  118.670 83.832  1.00 24.77 ? 206 TRP A CD1   1 
ATOM   1536 C  CD2   . TRP A 1 206 ? 83.086  119.713 81.921  1.00 24.77 ? 206 TRP A CD2   1 
ATOM   1537 N  NE1   . TRP A 1 206 ? 82.323  119.255 83.964  1.00 24.77 ? 206 TRP A NE1   1 
ATOM   1538 C  CE2   . TRP A 1 206 ? 82.013  119.903 82.800  1.00 24.77 ? 206 TRP A CE2   1 
ATOM   1539 C  CE3   . TRP A 1 206 ? 83.018  120.277 80.649  1.00 24.77 ? 206 TRP A CE3   1 
ATOM   1540 C  CZ2   . TRP A 1 206 ? 80.891  120.633 82.453  1.00 24.77 ? 206 TRP A CZ2   1 
ATOM   1541 C  CZ3   . TRP A 1 206 ? 81.908  121.003 80.310  1.00 24.77 ? 206 TRP A CZ3   1 
ATOM   1542 C  CH2   . TRP A 1 206 ? 80.860  121.181 81.206  1.00 24.77 ? 206 TRP A CH2   1 
ATOM   1543 N  N     . ALA A 1 207 ? 88.480  117.987 81.735  1.00 20.44 ? 207 ALA A N     1 
ATOM   1544 C  CA    . ALA A 1 207 ? 89.596  117.328 81.072  1.00 20.44 ? 207 ALA A CA    1 
ATOM   1545 C  C     . ALA A 1 207 ? 90.489  116.587 82.051  1.00 20.44 ? 207 ALA A C     1 
ATOM   1546 O  O     . ALA A 1 207 ? 90.850  115.429 81.822  1.00 20.44 ? 207 ALA A O     1 
ATOM   1547 C  CB    . ALA A 1 207 ? 90.399  118.361 80.294  1.00 20.44 ? 207 ALA A CB    1 
ATOM   1548 N  N     . TYR A 1 208 ? 90.851  117.241 83.152  1.00 21.84 ? 208 TYR A N     1 
ATOM   1549 C  CA    . TYR A 1 208 ? 91.591  116.594 84.227  1.00 21.84 ? 208 TYR A CA    1 
ATOM   1550 C  C     . TYR A 1 208 ? 90.848  115.399 84.805  1.00 21.84 ? 208 TYR A C     1 
ATOM   1551 O  O     . TYR A 1 208 ? 91.467  114.401 85.177  1.00 21.84 ? 208 TYR A O     1 
ATOM   1552 C  CB    . TYR A 1 208 ? 91.861  117.622 85.315  1.00 21.84 ? 208 TYR A CB    1 
ATOM   1553 C  CG    . TYR A 1 208 ? 92.666  117.150 86.496  1.00 21.84 ? 208 TYR A CG    1 
ATOM   1554 C  CD1   . TYR A 1 208 ? 94.032  116.996 86.408  1.00 21.84 ? 208 TYR A CD1   1 
ATOM   1555 C  CD2   . TYR A 1 208 ? 92.065  116.882 87.708  1.00 21.84 ? 208 TYR A CD2   1 
ATOM   1556 C  CE1   . TYR A 1 208 ? 94.760  116.558 87.468  1.00 21.84 ? 208 TYR A CE1   1 
ATOM   1557 C  CE2   . TYR A 1 208 ? 92.792  116.467 88.781  1.00 21.84 ? 208 TYR A CE2   1 
ATOM   1558 C  CZ    . TYR A 1 208 ? 94.137  116.301 88.655  1.00 21.84 ? 208 TYR A CZ    1 
ATOM   1559 O  OH    . TYR A 1 208 ? 94.873  115.919 89.742  1.00 21.84 ? 208 TYR A OH    1 
ATOM   1560 N  N     . ALA A 1 209 ? 89.531  115.482 84.905  1.00 17.79 ? 209 ALA A N     1 
ATOM   1561 C  CA    . ALA A 1 209 ? 88.751  114.407 85.497  1.00 17.79 ? 209 ALA A CA    1 
ATOM   1562 C  C     . ALA A 1 209 ? 88.483  113.257 84.547  1.00 17.79 ? 209 ALA A C     1 
ATOM   1563 O  O     . ALA A 1 209 ? 88.165  112.162 85.008  1.00 17.79 ? 209 ALA A O     1 
ATOM   1564 C  CB    . ALA A 1 209 ? 87.427  114.945 86.021  1.00 17.79 ? 209 ALA A CB    1 
ATOM   1565 N  N     . GLY A 1 210 ? 88.577  113.476 83.248  1.00 16.94 ? 210 GLY A N     1 
ATOM   1566 C  CA    . GLY A 1 210 ? 88.300  112.437 82.283  1.00 16.94 ? 210 GLY A CA    1 
ATOM   1567 C  C     . GLY A 1 210 ? 86.970  112.561 81.590  1.00 16.94 ? 210 GLY A C     1 
ATOM   1568 O  O     . GLY A 1 210 ? 86.472  111.561 81.074  1.00 16.94 ? 210 GLY A O     1 
ATOM   1569 N  N     . TYR A 1 211 ? 86.387  113.756 81.570  1.00 19.43 ? 211 TYR A N     1 
ATOM   1570 C  CA    . TYR A 1 211 ? 85.080  114.037 80.994  1.00 19.43 ? 211 TYR A CA    1 
ATOM   1571 C  C     . TYR A 1 211 ? 85.133  114.891 79.726  1.00 19.43 ? 211 TYR A C     1 
ATOM   1572 O  O     . TYR A 1 211 ? 84.079  115.272 79.222  1.00 19.43 ? 211 TYR A O     1 
ATOM   1573 C  CB    . TYR A 1 211 ? 84.198  114.728 82.037  1.00 19.43 ? 211 TYR A CB    1 
ATOM   1574 C  CG    . TYR A 1 211 ? 83.634  113.799 83.075  1.00 19.43 ? 211 TYR A CG    1 
ATOM   1575 C  CD1   . TYR A 1 211 ? 82.936  112.666 82.704  1.00 19.43 ? 211 TYR A CD1   1 
ATOM   1576 C  CD2   . TYR A 1 211 ? 83.804  114.046 84.424  1.00 19.43 ? 211 TYR A CD2   1 
ATOM   1577 C  CE1   . TYR A 1 211 ? 82.422  111.831 83.632  1.00 19.43 ? 211 TYR A CE1   1 
ATOM   1578 C  CE2   . TYR A 1 211 ? 83.296  113.191 85.366  1.00 19.43 ? 211 TYR A CE2   1 
ATOM   1579 C  CZ    . TYR A 1 211 ? 82.602  112.092 84.959  1.00 19.43 ? 211 TYR A CZ    1 
ATOM   1580 O  OH    . TYR A 1 211 ? 82.079  111.214 85.873  1.00 19.43 ? 211 TYR A OH    1 
ATOM   1581 N  N     . SER A 1 212 ? 86.319  115.187 79.193  1.00 23.36 ? 212 SER A N     1 
ATOM   1582 C  CA    . SER A 1 212 ? 86.466  115.970 77.968  1.00 23.36 ? 212 SER A CA    1 
ATOM   1583 C  C     . SER A 1 212 ? 86.099  115.152 76.724  1.00 23.36 ? 212 SER A C     1 
ATOM   1584 O  O     . SER A 1 212 ? 85.943  113.932 76.775  1.00 23.36 ? 212 SER A O     1 
ATOM   1585 C  CB    . SER A 1 212 ? 87.891  116.495 77.863  1.00 23.36 ? 212 SER A CB    1 
ATOM   1586 O  OG    . SER A 1 212 ? 88.096  117.212 76.672  1.00 23.36 ? 212 SER A OG    1 
ATOM   1587 N  N     . VAL A 1 213 ? 85.944  115.851 75.590  1.00 34.19 ? 213 VAL A N     1 
ATOM   1588 C  CA    . VAL A 1 213 ? 85.599  115.225 74.311  1.00 34.19 ? 213 VAL A CA    1 
ATOM   1589 C  C     . VAL A 1 213 ? 86.445  115.808 73.175  1.00 34.19 ? 213 VAL A C     1 
ATOM   1590 O  O     . VAL A 1 213 ? 86.583  117.030 73.066  1.00 34.19 ? 213 VAL A O     1 
ATOM   1591 C  CB    . VAL A 1 213 ? 84.102  115.407 73.986  1.00 34.19 ? 213 VAL A CB    1 
ATOM   1592 C  CG1   . VAL A 1 213 ? 83.715  114.506 72.867  1.00 34.19 ? 213 VAL A CG1   1 
ATOM   1593 C  CG2   . VAL A 1 213 ? 83.219  115.161 75.201  1.00 34.19 ? 213 VAL A CG2   1 
ATOM   1594 N  N     . ASP A 1 214 ? 87.008  114.942 72.323  1.00 44.64 ? 214 ASP A N     1 
ATOM   1595 C  CA    . ASP A 1 214 ? 87.626  115.352 71.055  1.00 44.64 ? 214 ASP A CA    1 
ATOM   1596 C  C     . ASP A 1 214 ? 86.822  114.812 69.877  1.00 44.64 ? 214 ASP A C     1 
ATOM   1597 O  O     . ASP A 1 214 ? 86.700  113.595 69.723  1.00 44.64 ? 214 ASP A O     1 
ATOM   1598 C  CB    . ASP A 1 214 ? 89.065  114.844 70.928  1.00 44.64 ? 214 ASP A CB    1 
ATOM   1599 C  CG    . ASP A 1 214 ? 90.055  115.585 71.812  1.00 44.64 ? 214 ASP A CG    1 
ATOM   1600 O  OD1   . ASP A 1 214 ? 89.802  116.751 72.175  1.00 44.64 ? 214 ASP A OD1   1 
ATOM   1601 O  OD2   . ASP A 1 214 ? 91.111  114.999 72.122  1.00 44.64 ? 214 ASP A OD2   1 
ATOM   1602 N  N     . ASN A 1 215 ? 86.326  115.711 69.015  1.00 45.31 ? 215 ASN A N     1 
ATOM   1603 C  CA    . ASN A 1 215 ? 85.584  115.323 67.803  1.00 45.31 ? 215 ASN A CA    1 
ATOM   1604 C  C     . ASN A 1 215 ? 84.455  114.335 68.092  1.00 45.31 ? 215 ASN A C     1 
ATOM   1605 O  O     . ASN A 1 215 ? 84.152  113.467 67.270  1.00 45.31 ? 215 ASN A O     1 
ATOM   1606 C  CB    . ASN A 1 215 ? 86.511  114.755 66.720  1.00 45.31 ? 215 ASN A CB    1 
ATOM   1607 C  CG    . ASN A 1 215 ? 87.662  115.674 66.389  1.00 45.31 ? 215 ASN A CG    1 
ATOM   1608 O  OD1   . ASN A 1 215 ? 87.458  116.792 65.915  1.00 45.31 ? 215 ASN A OD1   1 
ATOM   1609 N  ND2   . ASN A 1 215 ? 88.880  115.211 66.628  1.00 45.31 ? 215 ASN A ND2   1 
ATOM   1610 N  N     . GLY A 1 216 ? 83.828  114.449 69.258  1.00 39.04 ? 216 GLY A N     1 
ATOM   1611 C  CA    . GLY A 1 216 ? 82.826  113.494 69.686  1.00 39.04 ? 216 GLY A CA    1 
ATOM   1612 C  C     . GLY A 1 216 ? 83.338  112.185 70.241  1.00 39.04 ? 216 GLY A C     1 
ATOM   1613 O  O     . GLY A 1 216 ? 82.562  111.232 70.333  1.00 39.04 ? 216 GLY A O     1 
ATOM   1614 N  N     . LYS A 1 217 ? 84.618  112.085 70.572  1.00 37.35 ? 217 LYS A N     1 
ATOM   1615 C  CA    . LYS A 1 217 ? 85.206  110.870 71.122  1.00 37.35 ? 217 LYS A CA    1 
ATOM   1616 C  C     . LYS A 1 217 ? 85.669  111.077 72.563  1.00 37.35 ? 217 LYS A C     1 
ATOM   1617 O  O     . LYS A 1 217 ? 86.378  112.041 72.862  1.00 37.35 ? 217 LYS A O     1 
ATOM   1618 C  CB    . LYS A 1 217 ? 86.329  110.366 70.216  1.00 37.35 ? 217 LYS A CB    1 
ATOM   1619 C  CG    . LYS A 1 217 ? 85.801  110.084 68.818  1.00 37.35 ? 217 LYS A CG    1 
ATOM   1620 C  CD    . LYS A 1 217 ? 86.843  109.609 67.836  1.00 37.35 ? 217 LYS A CD    1 
ATOM   1621 C  CE    . LYS A 1 217 ? 86.200  109.407 66.476  1.00 37.35 ? 217 LYS A CE    1 
ATOM   1622 N  NZ    . LYS A 1 217 ? 87.197  109.112 65.418  1.00 37.35 ? 217 LYS A NZ    1 
ATOM   1623 N  N     . VAL A 1 218 ? 85.254  110.163 73.450  1.00 26.46 ? 218 VAL A N     1 
ATOM   1624 C  CA    . VAL A 1 218 ? 85.591  110.238 74.869  1.00 26.46 ? 218 VAL A CA    1 
ATOM   1625 C  C     . VAL A 1 218 ? 87.027  109.776 75.101  1.00 26.46 ? 218 VAL A C     1 
ATOM   1626 O  O     . VAL A 1 218 ? 87.647  109.124 74.264  1.00 26.46 ? 218 VAL A O     1 
ATOM   1627 C  CB    . VAL A 1 218 ? 84.613  109.417 75.737  1.00 26.46 ? 218 VAL A CB    1 
ATOM   1628 C  CG1   . VAL A 1 218 ? 83.191  109.812 75.496  1.00 26.46 ? 218 VAL A CG1   1 
ATOM   1629 C  CG2   . VAL A 1 218 ? 84.800  107.948 75.519  1.00 26.46 ? 218 VAL A CG2   1 
ATOM   1630 N  N     . GLN A 1 219 ? 87.555  110.147 76.268  1.00 19.99 ? 219 GLN A N     1 
ATOM   1631 C  CA    . GLN A 1 219 ? 88.789  109.591 76.814  1.00 19.99 ? 219 GLN A CA    1 
ATOM   1632 C  C     . GLN A 1 219 ? 88.584  108.146 77.249  1.00 19.99 ? 219 GLN A C     1 
ATOM   1633 O  O     . GLN A 1 219 ? 87.790  107.883 78.149  1.00 19.99 ? 219 GLN A O     1 
ATOM   1634 C  CB    . GLN A 1 219 ? 89.228  110.462 77.981  1.00 19.99 ? 219 GLN A CB    1 
ATOM   1635 C  CG    . GLN A 1 219 ? 89.736  111.808 77.520  1.00 19.99 ? 219 GLN A CG    1 
ATOM   1636 C  CD    . GLN A 1 219 ? 89.621  112.881 78.556  1.00 19.99 ? 219 GLN A CD    1 
ATOM   1637 O  OE1   . GLN A 1 219 ? 88.542  113.156 79.045  1.00 19.99 ? 219 GLN A OE1   1 
ATOM   1638 N  NE2   . GLN A 1 219 ? 90.720  113.530 78.861  1.00 19.99 ? 219 GLN A NE2   1 
ATOM   1639 N  N     . LYS A 1 220 ? 89.270  107.209 76.597  1.00 21.39 ? 220 LYS A N     1 
ATOM   1640 C  CA    . LYS A 1 220 ? 89.275  105.805 76.977  1.00 21.39 ? 220 LYS A CA    1 
ATOM   1641 C  C     . LYS A 1 220 ? 90.683  105.320 77.281  1.00 21.39 ? 220 LYS A C     1 
ATOM   1642 O  O     . LYS A 1 220 ? 91.644  105.752 76.654  1.00 21.39 ? 220 LYS A O     1 
ATOM   1643 C  CB    . LYS A 1 220 ? 88.701  104.917 75.878  1.00 21.39 ? 220 LYS A CB    1 
ATOM   1644 C  CG    . LYS A 1 220 ? 87.251  105.120 75.602  1.00 21.39 ? 220 LYS A CG    1 
ATOM   1645 C  CD    . LYS A 1 220 ? 86.706  103.994 74.756  1.00 21.39 ? 220 LYS A CD    1 
ATOM   1646 C  CE    . LYS A 1 220 ? 86.578  102.720 75.563  1.00 21.39 ? 220 LYS A CE    1 
ATOM   1647 N  NZ    . LYS A 1 220 ? 85.911  101.636 74.793  1.00 21.39 ? 220 LYS A NZ    1 
ATOM   1648 N  N     . ARG A 1 221 ? 90.798  104.395 78.228  1.00 23.75 ? 221 ARG A N     1 
ATOM   1649 C  CA    . ARG A 1 221 ? 92.043  103.662 78.404  1.00 23.75 ? 221 ARG A CA    1 
ATOM   1650 C  C     . ARG A 1 221 ? 92.414  102.927 77.121  1.00 23.75 ? 221 ARG A C     1 
ATOM   1651 O  O     . ARG A 1 221 ? 91.552  102.512 76.346  1.00 23.75 ? 221 ARG A O     1 
ATOM   1652 C  CB    . ARG A 1 221 ? 91.927  102.672 79.569  1.00 23.75 ? 221 ARG A CB    1 
ATOM   1653 C  CG    . ARG A 1 221 ? 91.751  103.320 80.939  1.00 23.75 ? 221 ARG A CG    1 
ATOM   1654 C  CD    . ARG A 1 221 ? 91.797  102.311 82.093  1.00 23.75 ? 221 ARG A CD    1 
ATOM   1655 N  NE    . ARG A 1 221 ? 90.644  101.420 82.127  1.00 23.75 ? 221 ARG A NE    1 
ATOM   1656 C  CZ    . ARG A 1 221 ? 90.507  100.385 82.949  1.00 23.75 ? 221 ARG A CZ    1 
ATOM   1657 N  NH1   . ARG A 1 221 ? 91.494  99.984  83.735  1.00 23.75 ? 221 ARG A NH1   1 
ATOM   1658 N  NH2   . ARG A 1 221 ? 89.363  99.713  82.960  1.00 23.75 ? 221 ARG A NH2   1 
ATOM   1659 N  N     . LYS A 1 222 ? 93.718  102.755 76.912  1.00 28.97 ? 222 LYS A N     1 
ATOM   1660 C  CA    . LYS A 1 222 ? 94.245  102.158 75.686  1.00 28.97 ? 222 LYS A CA    1 
ATOM   1661 C  C     . LYS A 1 222 ? 95.682  101.732 75.944  1.00 28.97 ? 222 LYS A C     1 
ATOM   1662 O  O     . LYS A 1 222 ? 96.545  102.593 76.123  1.00 28.97 ? 222 LYS A O     1 
ATOM   1663 C  CB    . LYS A 1 222 ? 94.175  103.171 74.555  1.00 28.97 ? 222 LYS A CB    1 
ATOM   1664 C  CG    . LYS A 1 222 ? 94.759  102.721 73.252  1.00 28.97 ? 222 LYS A CG    1 
ATOM   1665 C  CD    . LYS A 1 222 ? 94.599  103.795 72.204  1.00 28.97 ? 222 LYS A CD    1 
ATOM   1666 C  CE    . LYS A 1 222 ? 95.265  103.390 70.903  1.00 28.97 ? 222 LYS A CE    1 
ATOM   1667 N  NZ    . LYS A 1 222 ? 95.105  104.431 69.849  1.00 28.97 ? 222 LYS A NZ    1 
ATOM   1668 N  N     . LYS A 1 223 ? 95.943  100.427 75.957  1.00 31.15 ? 223 LYS A N     1 
ATOM   1669 C  CA    . LYS A 1 223 ? 97.286  99.941  76.245  1.00 31.15 ? 223 LYS A CA    1 
ATOM   1670 C  C     . LYS A 1 223 ? 98.318  100.511 75.282  1.00 31.15 ? 223 LYS A C     1 
ATOM   1671 O  O     . LYS A 1 223 ? 98.042  100.740 74.103  1.00 31.15 ? 223 LYS A O     1 
ATOM   1672 C  CB    . LYS A 1 223 ? 97.326  98.417  76.242  1.00 31.15 ? 223 LYS A CB    1 
ATOM   1673 C  CG    . LYS A 1 223 ? 96.697  97.885  77.507  1.00 31.15 ? 223 LYS A CG    1 
ATOM   1674 C  CD    . LYS A 1 223 ? 96.809  96.423  77.715  1.00 31.15 ? 223 LYS A CD    1 
ATOM   1675 C  CE    . LYS A 1 223 ? 95.992  96.042  78.946  1.00 31.15 ? 223 LYS A CE    1 
ATOM   1676 N  NZ    . LYS A 1 223 ? 96.360  94.715  79.499  1.00 31.15 ? 223 LYS A NZ    1 
ATOM   1677 N  N     . GLY A 1 224 ? 99.505  100.776 75.812  1.00 29.52 ? 224 GLY A N     1 
ATOM   1678 C  CA    . GLY A 1 224 ? 100.553 101.435 75.075  1.00 29.52 ? 224 GLY A CA    1 
ATOM   1679 C  C     . GLY A 1 224 ? 100.372 102.914 74.848  1.00 29.52 ? 224 GLY A C     1 
ATOM   1680 O  O     . GLY A 1 224 ? 101.200 103.512 74.155  1.00 29.52 ? 224 GLY A O     1 
ATOM   1681 N  N     . VAL A 1 225 ? 99.318  103.530 75.376  1.00 27.13 ? 225 VAL A N     1 
ATOM   1682 C  CA    . VAL A 1 225 ? 99.151  104.977 75.305  1.00 27.13 ? 225 VAL A CA    1 
ATOM   1683 C  C     . VAL A 1 225 ? 98.938  105.529 76.705  1.00 27.13 ? 225 VAL A C     1 
ATOM   1684 O  O     . VAL A 1 225 ? 97.962  105.177 77.370  1.00 27.13 ? 225 VAL A O     1 
ATOM   1685 C  CB    . VAL A 1 225 ? 97.990  105.379 74.386  1.00 27.13 ? 225 VAL A CB    1 
ATOM   1686 C  CG1   . VAL A 1 225 ? 97.880  106.892 74.315  1.00 27.13 ? 225 VAL A CG1   1 
ATOM   1687 C  CG2   . VAL A 1 225 ? 98.212  104.810 73.008  1.00 27.13 ? 225 VAL A CG2   1 
ATOM   1688 N  N     . ALA A 1 226 ? 99.821  106.422 77.134  1.00 26.42 ? 226 ALA A N     1 
ATOM   1689 C  CA    . ALA A 1 226 ? 99.645  107.076 78.419  1.00 26.42 ? 226 ALA A CA    1 
ATOM   1690 C  C     . ALA A 1 226 ? 98.360  107.883 78.421  1.00 26.42 ? 226 ALA A C     1 
ATOM   1691 O  O     . ALA A 1 226 ? 98.061  108.613 77.475  1.00 26.42 ? 226 ALA A O     1 
ATOM   1692 C  CB    . ALA A 1 226 ? 100.834 107.974 78.732  1.00 26.42 ? 226 ALA A CB    1 
ATOM   1693 N  N     . SER A 1 227 ? 97.588  107.719 79.482  1.00 21.59 ? 227 SER A N     1 
ATOM   1694 C  CA    . SER A 1 227 ? 96.415  108.526 79.717  1.00 21.59 ? 227 SER A CA    1 
ATOM   1695 C  C     . SER A 1 227 ? 96.837  109.919 80.164  1.00 21.59 ? 227 SER A C     1 
ATOM   1696 O  O     . SER A 1 227 ? 98.002  110.179 80.448  1.00 21.59 ? 227 SER A O     1 
ATOM   1697 C  CB    . SER A 1 227 ? 95.531  107.816 80.740  1.00 21.59 ? 227 SER A CB    1 
ATOM   1698 O  OG    . SER A 1 227 ? 94.445  108.599 81.133  1.00 21.59 ? 227 SER A OG    1 
ATOM   1699 N  N     . ASN A 1 228 ? 95.892  110.837 80.184  1.00 21.23 ? 228 ASN A N     1 
ATOM   1700 C  CA    . ASN A 1 228 ? 96.201  112.197 80.605  1.00 21.23 ? 228 ASN A CA    1 
ATOM   1701 C  C     . ASN A 1 228 ? 95.068  112.805 81.419  1.00 21.23 ? 228 ASN A C     1 
ATOM   1702 O  O     . ASN A 1 228 ? 94.808  114.009 81.333  1.00 21.23 ? 228 ASN A O     1 
ATOM   1703 C  CB    . ASN A 1 228 ? 96.580  113.067 79.402  1.00 21.23 ? 228 ASN A CB    1 
ATOM   1704 C  CG    . ASN A 1 228 ? 95.423  113.359 78.493  1.00 21.23 ? 228 ASN A CG    1 
ATOM   1705 O  OD1   . ASN A 1 228 ? 94.532  112.534 78.320  1.00 21.23 ? 228 ASN A OD1   1 
ATOM   1706 N  ND2   . ASN A 1 228 ? 95.442  114.530 77.874  1.00 21.23 ? 228 ASN A ND2   1 
ATOM   1707 N  N     . TRP A 1 229 ? 94.378  111.980 82.198  1.00 15.55 ? 229 TRP A N     1 
ATOM   1708 C  CA    . TRP A 1 229 ? 93.393  112.430 83.164  1.00 15.55 ? 229 TRP A CA    1 
ATOM   1709 C  C     . TRP A 1 229 ? 93.541  111.605 84.435  1.00 15.55 ? 229 TRP A C     1 
ATOM   1710 O  O     . TRP A 1 229 ? 94.017  110.467 84.411  1.00 15.55 ? 229 TRP A O     1 
ATOM   1711 C  CB    . TRP A 1 229 ? 91.967  112.334 82.610  1.00 15.55 ? 229 TRP A CB    1 
ATOM   1712 C  CG    . TRP A 1 229 ? 91.544  110.943 82.272  1.00 15.55 ? 229 TRP A CG    1 
ATOM   1713 C  CD1   . TRP A 1 229 ? 90.791  110.115 83.030  1.00 15.55 ? 229 TRP A CD1   1 
ATOM   1714 C  CD2   . TRP A 1 229 ? 91.831  110.233 81.070  1.00 15.55 ? 229 TRP A CD2   1 
ATOM   1715 N  NE1   . TRP A 1 229 ? 90.610  108.924 82.397  1.00 15.55 ? 229 TRP A NE1   1 
ATOM   1716 C  CE2   . TRP A 1 229 ? 91.237  108.971 81.184  1.00 15.55 ? 229 TRP A CE2   1 
ATOM   1717 C  CE3   . TRP A 1 229 ? 92.539  110.539 79.911  1.00 15.55 ? 229 TRP A CE3   1 
ATOM   1718 C  CZ2   . TRP A 1 229 ? 91.335  108.012 80.185  1.00 15.55 ? 229 TRP A CZ2   1 
ATOM   1719 C  CZ3   . TRP A 1 229 ? 92.624  109.594 78.926  1.00 15.55 ? 229 TRP A CZ3   1 
ATOM   1720 C  CH2   . TRP A 1 229 ? 92.030  108.345 79.067  1.00 15.55 ? 229 TRP A CH2   1 
ATOM   1721 N  N     . LYS A 1 230 ? 93.150  112.209 85.548  1.00 12.91 ? 230 LYS A N     1 
ATOM   1722 C  CA    . LYS A 1 230 ? 93.053  111.545 86.841  1.00 12.91 ? 230 LYS A CA    1 
ATOM   1723 C  C     . LYS A 1 230 ? 91.745  110.768 86.898  1.00 12.91 ? 230 LYS A C     1 
ATOM   1724 O  O     . LYS A 1 230 ? 90.691  111.308 87.201  1.00 12.91 ? 230 LYS A O     1 
ATOM   1725 C  CB    . LYS A 1 230 ? 93.151  112.580 87.953  1.00 12.91 ? 230 LYS A CB    1 
ATOM   1726 C  CG    . LYS A 1 230 ? 93.228  112.040 89.346  1.00 12.91 ? 230 LYS A CG    1 
ATOM   1727 C  CD    . LYS A 1 230 ? 93.504  113.163 90.321  1.00 12.91 ? 230 LYS A CD    1 
ATOM   1728 C  CE    . LYS A 1 230 ? 93.711  112.629 91.721  1.00 12.91 ? 230 LYS A CE    1 
ATOM   1729 N  NZ    . LYS A 1 230 ? 94.157  113.689 92.643  1.00 12.91 ? 230 LYS A NZ    1 
ATOM   1730 N  N     . ASN A 1 231 ? 91.796  109.497 86.535  1.00 14.02 ? 231 ASN A N     1 
ATOM   1731 C  CA    . ASN A 1 231 ? 90.590  108.689 86.425  1.00 14.02 ? 231 ASN A CA    1 
ATOM   1732 C  C     . ASN A 1 231 ? 89.867  108.448 87.748  1.00 14.02 ? 231 ASN A C     1 
ATOM   1733 O  O     . ASN A 1 231 ? 88.671  108.135 87.734  1.00 14.02 ? 231 ASN A O     1 
ATOM   1734 C  CB    . ASN A 1 231 ? 90.947  107.355 85.800  1.00 14.02 ? 231 ASN A CB    1 
ATOM   1735 C  CG    . ASN A 1 231 ? 89.753  106.600 85.325  1.00 14.02 ? 231 ASN A CG    1 
ATOM   1736 O  OD1   . ASN A 1 231 ? 88.916  107.123 84.615  1.00 14.02 ? 231 ASN A OD1   1 
ATOM   1737 N  ND2   . ASN A 1 231 ? 89.688  105.337 85.689  1.00 14.02 ? 231 ASN A ND2   1 
ATOM   1738 N  N     . LYS A 1 232 ? 90.552  108.546 88.884  1.00 15.61 ? 232 LYS A N     1 
ATOM   1739 C  CA    . LYS A 1 232 ? 89.874  108.360 90.161  1.00 15.61 ? 232 LYS A CA    1 
ATOM   1740 C  C     . LYS A 1 232 ? 88.753  109.368 90.401  1.00 15.61 ? 232 LYS A C     1 
ATOM   1741 O  O     . LYS A 1 232 ? 87.753  109.022 91.027  1.00 15.61 ? 232 LYS A O     1 
ATOM   1742 C  CB    . LYS A 1 232 ? 90.888  108.368 91.300  1.00 15.61 ? 232 LYS A CB    1 
ATOM   1743 C  CG    . LYS A 1 232 ? 91.860  107.211 91.215  1.00 15.61 ? 232 LYS A CG    1 
ATOM   1744 C  CD    . LYS A 1 232 ? 92.607  106.967 92.502  1.00 15.61 ? 232 LYS A CD    1 
ATOM   1745 C  CE    . LYS A 1 232 ? 93.407  108.160 92.935  1.00 15.61 ? 232 LYS A CE    1 
ATOM   1746 N  NZ    . LYS A 1 232 ? 94.308  107.809 94.062  1.00 15.61 ? 232 LYS A NZ    1 
ATOM   1747 N  N     . ILE A 1 233 ? 88.869  110.603 89.912  1.00 14.26 ? 233 ILE A N     1 
ATOM   1748 C  CA    . ILE A 1 233 ? 87.733  111.515 90.067  1.00 14.26 ? 233 ILE A CA    1 
ATOM   1749 C  C     . ILE A 1 233 ? 86.540  111.138 89.193  1.00 14.26 ? 233 ILE A C     1 
ATOM   1750 O  O     . ILE A 1 233 ? 85.401  111.298 89.621  1.00 14.26 ? 233 ILE A O     1 
ATOM   1751 C  CB    . ILE A 1 233 ? 88.138  112.998 89.890  1.00 14.26 ? 233 ILE A CB    1 
ATOM   1752 C  CG1   . ILE A 1 233 ? 86.907  113.907 89.767  1.00 14.26 ? 233 ILE A CG1   1 
ATOM   1753 C  CG2   . ILE A 1 233 ? 89.135  113.222 88.831  1.00 14.26 ? 233 ILE A CG2   1 
ATOM   1754 C  CD1   . ILE A 1 233 ? 86.099  114.076 91.053  1.00 14.26 ? 233 ILE A CD1   1 
ATOM   1755 N  N     . ARG A 1 234 ? 86.748  110.578 88.008  1.00 13.82 ? 234 ARG A N     1 
ATOM   1756 C  CA    . ARG A 1 234 ? 85.610  110.066 87.238  1.00 13.82 ? 234 ARG A CA    1 
ATOM   1757 C  C     . ARG A 1 234 ? 84.985  108.808 87.855  1.00 13.82 ? 234 ARG A C     1 
ATOM   1758 O  O     . ARG A 1 234 ? 83.752  108.677 87.884  1.00 13.82 ? 234 ARG A O     1 
ATOM   1759 C  CB    . ARG A 1 234 ? 86.042  109.827 85.788  1.00 13.82 ? 234 ARG A CB    1 
ATOM   1760 C  CG    . ARG A 1 234 ? 84.968  109.320 84.841  1.00 13.82 ? 234 ARG A CG    1 
ATOM   1761 C  CD    . ARG A 1 234 ? 85.474  109.262 83.407  1.00 13.82 ? 234 ARG A CD    1 
ATOM   1762 N  NE    . ARG A 1 234 ? 86.383  108.150 83.149  1.00 13.82 ? 234 ARG A NE    1 
ATOM   1763 C  CZ    . ARG A 1 234 ? 86.903  107.864 81.963  1.00 13.82 ? 234 ARG A CZ    1 
ATOM   1764 N  NH1   . ARG A 1 234 ? 86.786  108.689 80.944  1.00 13.82 ? 234 ARG A NH1   1 
ATOM   1765 N  NH2   . ARG A 1 234 ? 87.618  106.754 81.818  1.00 13.82 ? 234 ARG A NH2   1 
ATOM   1766 N  N     . THR A 1 235 ? 85.792  107.929 88.451  1.00 9.37  ? 235 THR A N     1 
ATOM   1767 C  CA    . THR A 1 235 ? 85.225  106.854 89.268  1.00 9.37  ? 235 THR A CA    1 
ATOM   1768 C  C     . THR A 1 235 ? 84.463  107.375 90.486  1.00 9.37  ? 235 THR A C     1 
ATOM   1769 O  O     . THR A 1 235 ? 83.435  106.812 90.863  1.00 9.37  ? 235 THR A O     1 
ATOM   1770 C  CB    . THR A 1 235 ? 86.325  105.890 89.707  1.00 9.37  ? 235 THR A CB    1 
ATOM   1771 O  OG1   . THR A 1 235 ? 86.736  105.090 88.600  1.00 9.37  ? 235 THR A OG1   1 
ATOM   1772 C  CG2   . THR A 1 235 ? 85.814  104.966 90.768  1.00 9.37  ? 235 THR A CG2   1 
ATOM   1773 N  N     . HIS A 1 236 ? 84.938  108.440 91.113  1.00 17.66 ? 236 HIS A N     1 
ATOM   1774 C  CA    . HIS A 1 236 ? 84.254  108.997 92.275  1.00 17.66 ? 236 HIS A CA    1 
ATOM   1775 C  C     . HIS A 1 236 ? 82.933  109.652 91.892  1.00 17.66 ? 236 HIS A C     1 
ATOM   1776 O  O     . HIS A 1 236 ? 81.908  109.476 92.566  1.00 17.66 ? 236 HIS A O     1 
ATOM   1777 C  CB    . HIS A 1 236 ? 85.180  110.018 92.938  1.00 17.66 ? 236 HIS A CB    1 
ATOM   1778 C  CG    . HIS A 1 236 ? 84.731  110.469 94.287  1.00 17.66 ? 236 HIS A CG    1 
ATOM   1779 N  ND1   . HIS A 1 236 ? 84.680  109.629 95.375  1.00 17.66 ? 236 HIS A ND1   1 
ATOM   1780 C  CD2   . HIS A 1 236 ? 84.337  111.682 94.727  1.00 17.66 ? 236 HIS A CD2   1 
ATOM   1781 C  CE1   . HIS A 1 236 ? 84.251  110.303 96.424  1.00 17.66 ? 236 HIS A CE1   1 
ATOM   1782 N  NE2   . HIS A 1 236 ? 84.027  111.548 96.054  1.00 17.66 ? 236 HIS A NE2   1 
ATOM   1783 N  N     . CYS A 1 237 ? 82.962  110.462 90.842  1.00 14.60 ? 237 CYS A N     1 
ATOM   1784 C  CA    . CYS A 1 237 ? 81.760  111.071 90.303  1.00 14.60 ? 237 CYS A CA    1 
ATOM   1785 C  C     . CYS A 1 237 ? 80.701  110.042 89.950  1.00 14.60 ? 237 CYS A C     1 
ATOM   1786 O  O     . CYS A 1 237 ? 79.508  110.303 90.108  1.00 14.60 ? 237 CYS A O     1 
ATOM   1787 C  CB    . CYS A 1 237 ? 82.132  111.917 89.101  1.00 14.60 ? 237 CYS A CB    1 
ATOM   1788 S  SG    . CYS A 1 237 ? 82.770  113.527 89.577  1.00 14.60 ? 237 CYS A SG    1 
ATOM   1789 N  N     . TYR A 1 238 ? 81.104  108.867 89.470  1.00 12.49 ? 238 TYR A N     1 
ATOM   1790 C  CA    . TYR A 1 238 ? 80.121  107.811 89.251  1.00 12.49 ? 238 TYR A CA    1 
ATOM   1791 C  C     . TYR A 1 238 ? 79.290  107.495 90.493  1.00 12.49 ? 238 TYR A C     1 
ATOM   1792 O  O     . TYR A 1 238 ? 78.066  107.351 90.409  1.00 12.49 ? 238 TYR A O     1 
ATOM   1793 C  CB    . TYR A 1 238 ? 80.834  106.559 88.768  1.00 12.49 ? 238 TYR A CB    1 
ATOM   1794 C  CG    . TYR A 1 238 ? 79.922  105.414 88.469  1.00 12.49 ? 238 TYR A CG    1 
ATOM   1795 C  CD1   . TYR A 1 238 ? 79.316  105.303 87.239  1.00 12.49 ? 238 TYR A CD1   1 
ATOM   1796 C  CD2   . TYR A 1 238 ? 79.678  104.437 89.416  1.00 12.49 ? 238 TYR A CD2   1 
ATOM   1797 C  CE1   . TYR A 1 238 ? 78.498  104.250 86.951  1.00 12.49 ? 238 TYR A CE1   1 
ATOM   1798 C  CE2   . TYR A 1 238 ? 78.844  103.383 89.144  1.00 12.49 ? 238 TYR A CE2   1 
ATOM   1799 C  CZ    . TYR A 1 238 ? 78.263  103.294 87.909  1.00 12.49 ? 238 TYR A CZ    1 
ATOM   1800 O  OH    . TYR A 1 238 ? 77.419  102.248 87.651  1.00 12.49 ? 238 TYR A OH    1 
ATOM   1801 N  N     . ASN A 1 239 ? 79.929  107.428 91.659  1.00 11.73 ? 239 ASN A N     1 
ATOM   1802 C  CA    . ASN A 1 239 ? 79.235  107.179 92.919  1.00 11.73 ? 239 ASN A CA    1 
ATOM   1803 C  C     . ASN A 1 239 ? 78.464  108.382 93.444  1.00 11.73 ? 239 ASN A C     1 
ATOM   1804 O  O     . ASN A 1 239 ? 77.400  108.211 94.039  1.00 11.73 ? 239 ASN A O     1 
ATOM   1805 C  CB    . ASN A 1 239 ? 80.247  106.685 93.933  1.00 11.73 ? 239 ASN A CB    1 
ATOM   1806 C  CG    . ASN A 1 239 ? 80.746  105.309 93.604  1.00 11.73 ? 239 ASN A CG    1 
ATOM   1807 O  OD1   . ASN A 1 239 ? 79.972  104.436 93.257  1.00 11.73 ? 239 ASN A OD1   1 
ATOM   1808 N  ND2   . ASN A 1 239 ? 82.034  105.103 93.720  1.00 11.73 ? 239 ASN A ND2   1 
ATOM   1809 N  N     . ILE A 1 240 ? 78.948  109.596 93.208  1.00 12.13 ? 240 ILE A N     1 
ATOM   1810 C  CA    . ILE A 1 240 ? 78.147  110.777 93.526  1.00 12.13 ? 240 ILE A CA    1 
ATOM   1811 C  C     . ILE A 1 240 ? 76.832  110.771 92.744  1.00 12.13 ? 240 ILE A C     1 
ATOM   1812 O  O     . ILE A 1 240 ? 75.756  111.056 93.286  1.00 12.13 ? 240 ILE A O     1 
ATOM   1813 C  CB    . ILE A 1 240 ? 78.942  112.066 93.258  1.00 12.13 ? 240 ILE A CB    1 
ATOM   1814 C  CG1   . ILE A 1 240 ? 80.311  112.020 93.931  1.00 12.13 ? 240 ILE A CG1   1 
ATOM   1815 C  CG2   . ILE A 1 240 ? 78.138  113.271 93.686  1.00 12.13 ? 240 ILE A CG2   1 
ATOM   1816 C  CD1   . ILE A 1 240 ? 81.047  113.304 93.854  1.00 12.13 ? 240 ILE A CD1   1 
ATOM   1817 N  N     . VAL A 1 241 ? 76.900  110.461 91.455  1.00 15.21 ? 241 VAL A N     1 
ATOM   1818 C  CA    . VAL A 1 241 ? 75.691  110.404 90.642  1.00 15.21 ? 241 VAL A CA    1 
ATOM   1819 C  C     . VAL A 1 241 ? 74.811  109.224 91.028  1.00 15.21 ? 241 VAL A C     1 
ATOM   1820 O  O     . VAL A 1 241 ? 73.584  109.326 91.015  1.00 15.21 ? 241 VAL A O     1 
ATOM   1821 C  CB    . VAL A 1 241 ? 76.062  110.373 89.153  1.00 15.21 ? 241 VAL A CB    1 
ATOM   1822 C  CG1   . VAL A 1 241 ? 74.829  110.323 88.320  1.00 15.21 ? 241 VAL A CG1   1 
ATOM   1823 C  CG2   . VAL A 1 241 ? 76.818  111.602 88.810  1.00 15.21 ? 241 VAL A CG2   1 
ATOM   1824 N  N     . ASP A 1 242 ? 75.408  108.083 91.349  1.00 15.43 ? 242 ASP A N     1 
ATOM   1825 C  CA    . ASP A 1 242 ? 74.647  106.959 91.885  1.00 15.43 ? 242 ASP A CA    1 
ATOM   1826 C  C     . ASP A 1 242 ? 73.850  107.349 93.134  1.00 15.43 ? 242 ASP A C     1 
ATOM   1827 O  O     . ASP A 1 242 ? 72.658  107.036 93.245  1.00 15.43 ? 242 ASP A O     1 
ATOM   1828 C  CB    . ASP A 1 242 ? 75.638  105.824 92.152  1.00 15.43 ? 242 ASP A CB    1 
ATOM   1829 C  CG    . ASP A 1 242 ? 75.028  104.624 92.837  1.00 15.43 ? 242 ASP A CG    1 
ATOM   1830 O  OD1   . ASP A 1 242 ? 74.849  104.674 94.067  1.00 15.43 ? 242 ASP A OD1   1 
ATOM   1831 O  OD2   . ASP A 1 242 ? 74.800  103.597 92.170  1.00 15.43 ? 242 ASP A OD2   1 
ATOM   1832 N  N     . SER A 1 243 ? 74.460  108.101 94.041  1.00 18.76 ? 243 SER A N     1 
ATOM   1833 C  CA    . SER A 1 243 ? 73.726  108.636 95.184  1.00 18.76 ? 243 SER A CA    1 
ATOM   1834 C  C     . SER A 1 243 ? 72.599  109.584 94.774  1.00 18.76 ? 243 SER A C     1 
ATOM   1835 O  O     . SER A 1 243 ? 71.477  109.470 95.273  1.00 18.76 ? 243 SER A O     1 
ATOM   1836 C  CB    . SER A 1 243 ? 74.690  109.325 96.139  1.00 18.76 ? 243 SER A CB    1 
ATOM   1837 O  OG    . SER A 1 243 ? 74.045  109.603 97.359  1.00 18.76 ? 243 SER A OG    1 
ATOM   1838 N  N     . PHE A 1 244 ? 72.867  110.522 93.857  1.00 16.84 ? 244 PHE A N     1 
ATOM   1839 C  CA    . PHE A 1 244 ? 71.796  111.412 93.388  1.00 16.84 ? 244 PHE A CA    1 
ATOM   1840 C  C     . PHE A 1 244 ? 70.614  110.653 92.806  1.00 16.84 ? 244 PHE A C     1 
ATOM   1841 O  O     . PHE A 1 244 ? 69.461  111.046 92.993  1.00 16.84 ? 244 PHE A O     1 
ATOM   1842 C  CB    . PHE A 1 244 ? 72.289  112.373 92.310  1.00 16.84 ? 244 PHE A CB    1 
ATOM   1843 C  CG    . PHE A 1 244 ? 73.274  113.378 92.765  1.00 16.84 ? 244 PHE A CG    1 
ATOM   1844 C  CD1   . PHE A 1 244 ? 73.427  113.676 94.090  1.00 16.84 ? 244 PHE A CD1   1 
ATOM   1845 C  CD2   . PHE A 1 244 ? 73.992  114.100 91.841  1.00 16.84 ? 244 PHE A CD2   1 
ATOM   1846 C  CE1   . PHE A 1 244 ? 74.311  114.633 94.481  1.00 16.84 ? 244 PHE A CE1   1 
ATOM   1847 C  CE2   . PHE A 1 244 ? 74.867  115.059 92.234  1.00 16.84 ? 244 PHE A CE2   1 
ATOM   1848 C  CZ    . PHE A 1 244 ? 75.028  115.322 93.554  1.00 16.84 ? 244 PHE A CZ    1 
ATOM   1849 N  N     . ILE A 1 245 ? 70.885  109.588 92.074  1.00 19.73 ? 245 ILE A N     1 
ATOM   1850 C  CA    . ILE A 1 245 ? 69.832  108.736 91.539  1.00 19.73 ? 245 ILE A CA    1 
ATOM   1851 C  C     . ILE A 1 245 ? 69.034  108.069 92.656  1.00 19.73 ? 245 ILE A C     1 
ATOM   1852 O  O     . ILE A 1 245 ? 67.808  108.202 92.719  1.00 19.73 ? 245 ILE A O     1 
ATOM   1853 C  CB    . ILE A 1 245 ? 70.446  107.713 90.572  1.00 19.73 ? 245 ILE A CB    1 
ATOM   1854 C  CG1   . ILE A 1 245 ? 70.880  108.426 89.303  1.00 19.73 ? 245 ILE A CG1   1 
ATOM   1855 C  CG2   . ILE A 1 245 ? 69.487  106.586 90.264  1.00 19.73 ? 245 ILE A CG2   1 
ATOM   1856 C  CD1   . ILE A 1 245 ? 71.787  107.604 88.457  1.00 19.73 ? 245 ILE A CD1   1 
ATOM   1857 N  N     . LYS A 1 246 ? 69.711  107.373 93.579  1.00 18.49 ? 246 LYS A N     1 
ATOM   1858 C  CA    . LYS A 1 246 ? 68.978  106.591 94.585  1.00 18.49 ? 246 LYS A CA    1 
ATOM   1859 C  C     . LYS A 1 246 ? 68.255  107.444 95.619  1.00 18.49 ? 246 LYS A C     1 
ATOM   1860 O  O     . LYS A 1 246 ? 67.276  106.985 96.209  1.00 18.49 ? 246 LYS A O     1 
ATOM   1861 C  CB    . LYS A 1 246 ? 69.903  105.603 95.286  1.00 18.49 ? 246 LYS A CB    1 
ATOM   1862 C  CG    . LYS A 1 246 ? 70.402  104.534 94.349  1.00 18.49 ? 246 LYS A CG    1 
ATOM   1863 C  CD    . LYS A 1 246 ? 71.103  103.420 95.061  1.00 18.49 ? 246 LYS A CD    1 
ATOM   1864 C  CE    . LYS A 1 246 ? 72.191  103.908 95.935  1.00 18.49 ? 246 LYS A CE    1 
ATOM   1865 N  NZ    . LYS A 1 246 ? 73.261  102.889 95.913  1.00 18.49 ? 246 LYS A NZ    1 
ATOM   1866 N  N     . GLN A 1 247 ? 68.718  108.649 95.891  1.00 23.41 ? 247 GLN A N     1 
ATOM   1867 C  CA    . GLN A 1 247 ? 68.011  109.514 96.821  1.00 23.41 ? 247 GLN A CA    1 
ATOM   1868 C  C     . GLN A 1 247 ? 66.951  110.380 96.145  1.00 23.41 ? 247 GLN A C     1 
ATOM   1869 O  O     . GLN A 1 247 ? 66.168  111.031 96.843  1.00 23.41 ? 247 GLN A O     1 
ATOM   1870 C  CB    . GLN A 1 247 ? 69.015  110.389 97.567  1.00 23.41 ? 247 GLN A CB    1 
ATOM   1871 C  CG    . GLN A 1 247 ? 70.017  109.589 98.406  1.00 23.41 ? 247 GLN A CG    1 
ATOM   1872 C  CD    . GLN A 1 247 ? 69.394  108.836 99.549  1.00 23.41 ? 247 GLN A CD    1 
ATOM   1873 O  OE1   . GLN A 1 247 ? 68.311  109.174 100.013 1.00 23.41 ? 247 GLN A OE1   1 
ATOM   1874 N  NE2   . GLN A 1 247 ? 70.065  107.785 99.996  1.00 23.41 ? 247 GLN A NE2   1 
ATOM   1875 N  N     . ARG A 1 248 ? 66.898  110.387 94.816  1.00 24.81 ? 248 ARG A N     1 
ATOM   1876 C  CA    . ARG A 1 248 ? 66.125  111.351 94.019  1.00 24.81 ? 248 ARG A CA    1 
ATOM   1877 C  C     . ARG A 1 248 ? 66.399  112.802 94.408  1.00 24.81 ? 248 ARG A C     1 
ATOM   1878 O  O     . ARG A 1 248 ? 65.488  113.595 94.633  1.00 24.81 ? 248 ARG A O     1 
ATOM   1879 C  CB    . ARG A 1 248 ? 64.630  111.046 94.066  1.00 24.81 ? 248 ARG A CB    1 
ATOM   1880 C  CG    . ARG A 1 248 ? 64.283  109.681 93.517  1.00 24.81 ? 248 ARG A CG    1 
ATOM   1881 C  CD    . ARG A 1 248 ? 62.800  109.506 93.301  1.00 24.81 ? 248 ARG A CD    1 
ATOM   1882 N  NE    . ARG A 1 248 ? 62.494  108.136 92.913  1.00 24.81 ? 248 ARG A NE    1 
ATOM   1883 C  CZ    . ARG A 1 248 ? 62.256  107.732 91.674  1.00 24.81 ? 248 ARG A CZ    1 
ATOM   1884 N  NH1   . ARG A 1 248 ? 62.141  108.590 90.677  1.00 24.81 ? 248 ARG A NH1   1 
ATOM   1885 N  NH2   . ARG A 1 248 ? 62.114  106.431 91.434  1.00 24.81 ? 248 ARG A NH2   1 
ATOM   1886 N  N     . THR A 1 249 ? 67.682  113.140 94.468  1.00 26.20 ? 249 THR A N     1 
ATOM   1887 C  CA    . THR A 1 249 ? 68.175  114.426 94.945  1.00 26.20 ? 249 THR A CA    1 
ATOM   1888 C  C     . THR A 1 249 ? 67.768  115.570 94.021  1.00 26.20 ? 249 THR A C     1 
ATOM   1889 O  O     . THR A 1 249 ? 68.269  115.670 92.900  1.00 26.20 ? 249 THR A O     1 
ATOM   1890 C  CB    . THR A 1 249 ? 69.691  114.367 95.052  1.00 26.20 ? 249 THR A CB    1 
ATOM   1891 O  OG1   . THR A 1 249 ? 70.067  113.281 95.901  1.00 26.20 ? 249 THR A OG1   1 
ATOM   1892 C  CG2   . THR A 1 249 ? 70.236  115.667 95.594  1.00 26.20 ? 249 THR A CG2   1 
ATOM   1893 N  N     . SER A 1 250 ? 66.856  116.422 94.480  1.00 29.97 ? 250 SER A N     1 
ATOM   1894 C  CA    . SER A 1 250 ? 66.662  117.799 94.014  1.00 29.97 ? 250 SER A CA    1 
ATOM   1895 C  C     . SER A 1 250 ? 66.867  118.045 92.513  1.00 29.97 ? 250 SER A C     1 
ATOM   1896 O  O     . SER A 1 250 ? 66.303  117.327 91.683  1.00 29.97 ? 250 SER A O     1 
ATOM   1897 C  CB    . SER A 1 250 ? 67.565  118.733 94.830  1.00 29.97 ? 250 SER A CB    1 
ATOM   1898 O  OG    . SER A 1 250 ? 67.261  120.100 94.609  1.00 29.97 ? 250 SER A OG    1 
ATOM   1899 N  N     . VAL A 1 251 ? 67.676  119.056 92.160  1.00 29.60 ? 251 VAL A N     1 
ATOM   1900 C  CA    . VAL A 1 251 ? 67.951  119.392 90.759  1.00 29.60 ? 251 VAL A CA    1 
ATOM   1901 C  C     . VAL A 1 251 ? 68.540  118.208 89.989  1.00 29.60 ? 251 VAL A C     1 
ATOM   1902 O  O     . VAL A 1 251 ? 68.228  117.988 88.804  1.00 29.60 ? 251 VAL A O     1 
ATOM   1903 C  CB    . VAL A 1 251 ? 68.884  120.617 90.688  1.00 29.60 ? 251 VAL A CB    1 
ATOM   1904 C  CG1   . VAL A 1 251 ? 69.255  120.940 89.252  1.00 29.60 ? 251 VAL A CG1   1 
ATOM   1905 C  CG2   . VAL A 1 251 ? 68.256  121.830 91.353  1.00 29.60 ? 251 VAL A CG2   1 
ATOM   1906 N  N     . TYR A 1 252 ? 69.382  117.425 90.644  1.00 26.17 ? 252 TYR A N     1 
ATOM   1907 C  CA    . TYR A 1 252 ? 70.234  116.487 89.929  1.00 26.17 ? 252 TYR A CA    1 
ATOM   1908 C  C     . TYR A 1 252 ? 69.497  115.243 89.454  1.00 26.17 ? 252 TYR A C     1 
ATOM   1909 O  O     . TYR A 1 252 ? 69.789  114.738 88.367  1.00 26.17 ? 252 TYR A O     1 
ATOM   1910 C  CB    . TYR A 1 252 ? 71.422  116.141 90.820  1.00 26.17 ? 252 TYR A CB    1 
ATOM   1911 C  CG    . TYR A 1 252 ? 72.293  117.341 91.162  1.00 26.17 ? 252 TYR A CG    1 
ATOM   1912 C  CD1   . TYR A 1 252 ? 73.028  117.990 90.186  1.00 26.17 ? 252 TYR A CD1   1 
ATOM   1913 C  CD2   . TYR A 1 252 ? 72.353  117.842 92.454  1.00 26.17 ? 252 TYR A CD2   1 
ATOM   1914 C  CE1   . TYR A 1 252 ? 73.817  119.078 90.493  1.00 26.17 ? 252 TYR A CE1   1 
ATOM   1915 C  CE2   . TYR A 1 252 ? 73.138  118.933 92.763  1.00 26.17 ? 252 TYR A CE2   1 
ATOM   1916 C  CZ    . TYR A 1 252 ? 73.863  119.541 91.776  1.00 26.17 ? 252 TYR A CZ    1 
ATOM   1917 O  OH    . TYR A 1 252 ? 74.651  120.615 92.079  1.00 26.17 ? 252 TYR A OH    1 
ATOM   1918 N  N     . ARG A 1 253 ? 68.497  114.782 90.194  1.00 25.45 ? 253 ARG A N     1 
ATOM   1919 C  CA    . ARG A 1 253 ? 67.666  113.683 89.713  1.00 25.45 ? 253 ARG A CA    1 
ATOM   1920 C  C     . ARG A 1 253 ? 66.816  114.097 88.522  1.00 25.45 ? 253 ARG A C     1 
ATOM   1921 O  O     . ARG A 1 253 ? 66.618  113.311 87.588  1.00 25.45 ? 253 ARG A O     1 
ATOM   1922 C  CB    . ARG A 1 253 ? 66.788  113.171 90.846  1.00 25.45 ? 253 ARG A CB    1 
ATOM   1923 C  CG    . ARG A 1 253 ? 65.887  112.050 90.448  1.00 25.45 ? 253 ARG A CG    1 
ATOM   1924 C  CD    . ARG A 1 253 ? 66.622  110.793 90.117  1.00 25.45 ? 253 ARG A CD    1 
ATOM   1925 N  NE    . ARG A 1 253 ? 65.797  109.979 89.240  1.00 25.45 ? 253 ARG A NE    1 
ATOM   1926 C  CZ    . ARG A 1 253 ? 65.709  108.657 89.272  1.00 25.45 ? 253 ARG A CZ    1 
ATOM   1927 N  NH1   . ARG A 1 253 ? 66.261  107.947 90.237  1.00 25.45 ? 253 ARG A NH1   1 
ATOM   1928 N  NH2   . ARG A 1 253 ? 65.005  108.037 88.336  1.00 25.45 ? 253 ARG A NH2   1 
ATOM   1929 N  N     . GLU A 1 254 ? 66.271  115.309 88.560  1.00 30.32 ? 254 GLU A N     1 
ATOM   1930 C  CA    . GLU A 1 254 ? 65.533  115.839 87.421  1.00 30.32 ? 254 GLU A CA    1 
ATOM   1931 C  C     . GLU A 1 254 ? 66.400  115.867 86.174  1.00 30.32 ? 254 GLU A C     1 
ATOM   1932 O  O     . GLU A 1 254 ? 65.958  115.469 85.092  1.00 30.32 ? 254 GLU A O     1 
ATOM   1933 C  CB    . GLU A 1 254 ? 65.043  117.250 87.737  1.00 30.32 ? 254 GLU A CB    1 
ATOM   1934 C  CG    . GLU A 1 254 ? 64.067  117.358 88.902  1.00 30.32 ? 254 GLU A CG    1 
ATOM   1935 C  CD    . GLU A 1 254 ? 63.642  118.799 89.167  1.00 30.32 ? 254 GLU A CD    1 
ATOM   1936 O  OE1   . GLU A 1 254 ? 64.472  119.709 88.962  1.00 30.32 ? 254 GLU A OE1   1 
ATOM   1937 O  OE2   . GLU A 1 254 ? 62.480  119.026 89.573  1.00 30.32 ? 254 GLU A OE2   1 
ATOM   1938 N  N     . LEU A 1 255 ? 67.652  116.312 86.318  1.00 27.21 ? 255 LEU A N     1 
ATOM   1939 C  CA    . LEU A 1 255 ? 68.575  116.319 85.183  1.00 27.21 ? 255 LEU A CA    1 
ATOM   1940 C  C     . LEU A 1 255 ? 68.910  114.914 84.685  1.00 27.21 ? 255 LEU A C     1 
ATOM   1941 O  O     . LEU A 1 255 ? 69.006  114.688 83.471  1.00 27.21 ? 255 LEU A O     1 
ATOM   1942 C  CB    . LEU A 1 255 ? 69.836  117.091 85.556  1.00 27.21 ? 255 LEU A CB    1 
ATOM   1943 C  CG    . LEU A 1 255 ? 70.868  117.211 84.448  1.00 27.21 ? 255 LEU A CG    1 
ATOM   1944 C  CD1   . LEU A 1 255 ? 70.260  117.880 83.251  1.00 27.21 ? 255 LEU A CD1   1 
ATOM   1945 C  CD2   . LEU A 1 255 ? 72.020  118.041 84.945  1.00 27.21 ? 255 LEU A CD2   1 
ATOM   1946 N  N     . TYR A 1 256 ? 69.009  113.944 85.589  1.00 25.67 ? 256 TYR A N     1 
ATOM   1947 C  CA    . TYR A 1 256 ? 69.167  112.557 85.159  1.00 25.67 ? 256 TYR A CA    1 
ATOM   1948 C  C     . TYR A 1 256 ? 67.974  112.057 84.348  1.00 25.67 ? 256 TYR A C     1 
ATOM   1949 O  O     . TYR A 1 256 ? 68.148  111.490 83.267  1.00 25.67 ? 256 TYR A O     1 
ATOM   1950 C  CB    . TYR A 1 256 ? 69.398  111.667 86.369  1.00 25.67 ? 256 TYR A CB    1 
ATOM   1951 C  CG    . TYR A 1 256 ? 69.395  110.201 86.066  1.00 25.67 ? 256 TYR A CG    1 
ATOM   1952 C  CD1   . TYR A 1 256 ? 70.467  109.593 85.452  1.00 25.67 ? 256 TYR A CD1   1 
ATOM   1953 C  CD2   . TYR A 1 256 ? 68.318  109.417 86.424  1.00 25.67 ? 256 TYR A CD2   1 
ATOM   1954 C  CE1   . TYR A 1 256 ? 70.450  108.252 85.170  1.00 25.67 ? 256 TYR A CE1   1 
ATOM   1955 C  CE2   . TYR A 1 256 ? 68.301  108.073 86.164  1.00 25.67 ? 256 TYR A CE2   1 
ATOM   1956 C  CZ    . TYR A 1 256 ? 69.364  107.495 85.536  1.00 25.67 ? 256 TYR A CZ    1 
ATOM   1957 O  OH    . TYR A 1 256 ? 69.339  106.138 85.314  1.00 25.67 ? 256 TYR A OH    1 
ATOM   1958 N  N     . ASP A 1 257 ? 66.758  112.217 84.866  1.00 30.01 ? 257 ASP A N     1 
ATOM   1959 C  CA    . ASP A 1 257 ? 65.577  111.796 84.112  1.00 30.01 ? 257 ASP A CA    1 
ATOM   1960 C  C     . ASP A 1 257 ? 65.493  112.489 82.754  1.00 30.01 ? 257 ASP A C     1 
ATOM   1961 O  O     . ASP A 1 257 ? 65.229  111.848 81.730  1.00 30.01 ? 257 ASP A O     1 
ATOM   1962 C  CB    . ASP A 1 257 ? 64.309  112.090 84.905  1.00 30.01 ? 257 ASP A CB    1 
ATOM   1963 C  CG    . ASP A 1 257 ? 64.206  111.298 86.167  1.00 30.01 ? 257 ASP A CG    1 
ATOM   1964 O  OD1   . ASP A 1 257 ? 64.913  110.280 86.297  1.00 30.01 ? 257 ASP A OD1   1 
ATOM   1965 O  OD2   . ASP A 1 257 ? 63.403  111.699 87.037  1.00 30.01 ? 257 ASP A OD2   1 
ATOM   1966 N  N     . ALA A 1 258 ? 65.723  113.800 82.727  1.00 29.06 ? 258 ALA A N     1 
ATOM   1967 C  CA    . ALA A 1 258 ? 65.620  114.553 81.484  1.00 29.06 ? 258 ALA A CA    1 
ATOM   1968 C  C     . ALA A 1 258 ? 66.598  114.050 80.437  1.00 29.06 ? 258 ALA A C     1 
ATOM   1969 O  O     . ALA A 1 258 ? 66.212  113.778 79.297  1.00 29.06 ? 258 ALA A O     1 
ATOM   1970 C  CB    . ALA A 1 258 ? 65.845  116.039 81.754  1.00 29.06 ? 258 ALA A CB    1 
ATOM   1971 N  N     . GLU A 1 259 ? 67.864  113.877 80.813  1.00 31.80 ? 259 GLU A N     1 
ATOM   1972 C  CA    . GLU A 1 259 ? 68.843  113.382 79.850  1.00 31.80 ? 259 GLU A CA    1 
ATOM   1973 C  C     . GLU A 1 259 ? 68.596  111.926 79.462  1.00 31.80 ? 259 GLU A C     1 
ATOM   1974 O  O     . GLU A 1 259 ? 68.751  111.559 78.296  1.00 31.80 ? 259 GLU A O     1 
ATOM   1975 C  CB    . GLU A 1 259 ? 70.249  113.530 80.424  1.00 31.80 ? 259 GLU A CB    1 
ATOM   1976 C  CG    . GLU A 1 259 ? 71.342  113.279 79.420  1.00 31.80 ? 259 GLU A CG    1 
ATOM   1977 C  CD    . GLU A 1 259 ? 71.431  114.347 78.364  1.00 31.80 ? 259 GLU A CD    1 
ATOM   1978 O  OE1   . GLU A 1 259 ? 70.677  115.335 78.440  1.00 31.80 ? 259 GLU A OE1   1 
ATOM   1979 O  OE2   . GLU A 1 259 ? 72.266  114.200 77.453  1.00 31.80 ? 259 GLU A OE2   1 
ATOM   1980 N  N     . LYS A 1 260 ? 68.262  111.073 80.420  1.00 30.54 ? 260 LYS A N     1 
ATOM   1981 C  CA    . LYS A 1 260 ? 68.011  109.665 80.124  1.00 30.54 ? 260 LYS A CA    1 
ATOM   1982 C  C     . LYS A 1 260 ? 66.834  109.473 79.169  1.00 30.54 ? 260 LYS A C     1 
ATOM   1983 O  O     . LYS A 1 260 ? 66.831  108.529 78.372  1.00 30.54 ? 260 LYS A O     1 
ATOM   1984 C  CB    . LYS A 1 260 ? 67.789  108.932 81.443  1.00 30.54 ? 260 LYS A CB    1 
ATOM   1985 C  CG    . LYS A 1 260 ? 67.697  107.433 81.394  1.00 30.54 ? 260 LYS A CG    1 
ATOM   1986 C  CD    . LYS A 1 260 ? 67.000  107.000 82.667  1.00 30.54 ? 260 LYS A CD    1 
ATOM   1987 C  CE    . LYS A 1 260 ? 66.914  105.514 82.847  1.00 30.54 ? 260 LYS A CE    1 
ATOM   1988 N  NZ    . LYS A 1 260 ? 66.003  105.219 83.987  1.00 30.54 ? 260 LYS A NZ    1 
ATOM   1989 N  N     . ALA A 1 261 ? 65.814  110.335 79.252  1.00 31.25 ? 261 ALA A N     1 
ATOM   1990 C  CA    . ALA A 1 261 ? 64.747  110.350 78.251  1.00 31.25 ? 261 ALA A CA    1 
ATOM   1991 C  C     . ALA A 1 261 ? 65.206  110.927 76.914  1.00 31.25 ? 261 ALA A C     1 
ATOM   1992 O  O     . ALA A 1 261 ? 64.937  110.353 75.855  1.00 31.25 ? 261 ALA A O     1 
ATOM   1993 C  CB    . ALA A 1 261 ? 63.555  111.140 78.784  1.00 31.25 ? 261 ALA A CB    1 
ATOM   1994 N  N     . ARG A 1 262 ? 65.905  112.062 76.947  1.00 34.38 ? 262 ARG A N     1 
ATOM   1995 C  CA    . ARG A 1 262 ? 66.378  112.720 75.732  1.00 34.38 ? 262 ARG A CA    1 
ATOM   1996 C  C     . ARG A 1 262 ? 67.321  111.860 74.903  1.00 34.38 ? 262 ARG A C     1 
ATOM   1997 O  O     . ARG A 1 262 ? 67.333  111.972 73.674  1.00 34.38 ? 262 ARG A O     1 
ATOM   1998 C  CB    . ARG A 1 262 ? 67.057  114.032 76.110  1.00 34.38 ? 262 ARG A CB    1 
ATOM   1999 C  CG    . ARG A 1 262 ? 67.420  114.926 74.966  1.00 34.38 ? 262 ARG A CG    1 
ATOM   2000 C  CD    . ARG A 1 262 ? 68.014  116.205 75.500  1.00 34.38 ? 262 ARG A CD    1 
ATOM   2001 N  NE    . ARG A 1 262 ? 69.418  116.055 75.850  1.00 34.38 ? 262 ARG A NE    1 
ATOM   2002 C  CZ    . ARG A 1 262 ? 70.426  116.416 75.071  1.00 34.38 ? 262 ARG A CZ    1 
ATOM   2003 N  NH1   . ARG A 1 262 ? 70.220  117.026 73.914  1.00 34.38 ? 262 ARG A NH1   1 
ATOM   2004 N  NH2   . ARG A 1 262 ? 71.672  116.183 75.472  1.00 34.38 ? 262 ARG A NH2   1 
ATOM   2005 N  N     . GLN A 1 263 ? 68.128  111.019 75.539  1.00 34.97 ? 263 GLN A N     1 
ATOM   2006 C  CA    . GLN A 1 263 ? 69.168  110.288 74.826  1.00 34.97 ? 263 GLN A CA    1 
ATOM   2007 C  C     . GLN A 1 263 ? 68.761  108.923 74.284  1.00 34.97 ? 263 GLN A C     1 
ATOM   2008 O  O     . GLN A 1 263 ? 69.357  108.471 73.306  1.00 34.97 ? 263 GLN A O     1 
ATOM   2009 C  CB    . GLN A 1 263 ? 70.394  110.143 75.727  1.00 34.97 ? 263 GLN A CB    1 
ATOM   2010 C  CG    . GLN A 1 263 ? 71.124  111.468 75.976  1.00 34.97 ? 263 GLN A CG    1 
ATOM   2011 C  CD    . GLN A 1 263 ? 71.848  111.995 74.752  1.00 34.97 ? 263 GLN A CD    1 
ATOM   2012 O  OE1   . GLN A 1 263 ? 71.795  111.401 73.684  1.00 34.97 ? 263 GLN A OE1   1 
ATOM   2013 N  NE2   . GLN A 1 263 ? 72.541  113.108 74.909  1.00 34.97 ? 263 GLN A NE2   1 
ATOM   2014 N  N     . ARG A 1 264 ? 67.794  108.236 74.886  1.00 38.55 ? 264 ARG A N     1 
ATOM   2015 C  CA    . ARG A 1 264 ? 67.457  106.885 74.431  1.00 38.55 ? 264 ARG A CA    1 
ATOM   2016 C  C     . ARG A 1 264 ? 67.027  106.765 72.964  1.00 38.55 ? 264 ARG A C     1 
ATOM   2017 O  O     . ARG A 1 264 ? 67.285  105.703 72.372  1.00 38.55 ? 264 ARG A O     1 
ATOM   2018 C  CB    . ARG A 1 264 ? 66.395  106.286 75.363  1.00 38.55 ? 264 ARG A CB    1 
ATOM   2019 C  CG    . ARG A 1 264 ? 66.063  104.837 75.088  1.00 38.55 ? 264 ARG A CG    1 
ATOM   2020 C  CD    . ARG A 1 264 ? 67.288  103.960 75.009  1.00 38.55 ? 264 ARG A CD    1 
ATOM   2021 N  NE    . ARG A 1 264 ? 66.929  102.549 75.034  1.00 38.55 ? 264 ARG A NE    1 
ATOM   2022 C  CZ    . ARG A 1 264 ? 67.014  101.713 74.010  1.00 38.55 ? 264 ARG A CZ    1 
ATOM   2023 N  NH1   . ARG A 1 264 ? 67.507  102.092 72.847  1.00 38.55 ? 264 ARG A NH1   1 
ATOM   2024 N  NH2   . ARG A 1 264 ? 66.620  100.454 74.168  1.00 38.55 ? 264 ARG A NH2   1 
ATOM   2025 N  N     . PRO A 1 265 ? 66.390  107.755 72.335  1.00 38.30 ? 265 PRO A N     1 
ATOM   2026 C  CA    . PRO A 1 265 ? 66.225  107.709 70.873  1.00 38.30 ? 265 PRO A CA    1 
ATOM   2027 C  C     . PRO A 1 265 ? 67.517  107.541 70.078  1.00 38.30 ? 265 PRO A C     1 
ATOM   2028 O  O     . PRO A 1 265 ? 67.453  107.090 68.930  1.00 38.30 ? 265 PRO A O     1 
ATOM   2029 C  CB    . PRO A 1 265 ? 65.560  109.056 70.566  1.00 38.30 ? 265 PRO A CB    1 
ATOM   2030 C  CG    . PRO A 1 265 ? 64.795  109.353 71.768  1.00 38.30 ? 265 PRO A CG    1 
ATOM   2031 C  CD    . PRO A 1 265 ? 65.649  108.894 72.904  1.00 38.30 ? 265 PRO A CD    1 
ATOM   2032 N  N     . LYS A 1 266 ? 68.675  107.899 70.634  1.00 38.57 ? 266 LYS A N     1 
ATOM   2033 C  CA    . LYS A 1 266 ? 69.936  107.961 69.901  1.00 38.57 ? 266 LYS A CA    1 
ATOM   2034 C  C     . LYS A 1 266 ? 70.855  106.753 70.097  1.00 38.57 ? 266 LYS A C     1 
ATOM   2035 O  O     . LYS A 1 266 ? 71.935  106.726 69.505  1.00 38.57 ? 266 LYS A O     1 
ATOM   2036 C  CB    . LYS A 1 266 ? 70.696  109.231 70.295  1.00 38.57 ? 266 LYS A CB    1 
ATOM   2037 C  CG    . LYS A 1 266 ? 69.862  110.495 70.265  1.00 38.57 ? 266 LYS A CG    1 
ATOM   2038 C  CD    . LYS A 1 266 ? 70.737  111.713 70.410  1.00 38.57 ? 266 LYS A CD    1 
ATOM   2039 C  CE    . LYS A 1 266 ? 69.921  112.944 70.699  1.00 38.57 ? 266 LYS A CE    1 
ATOM   2040 N  NZ    . LYS A 1 266 ? 70.733  114.189 70.598  1.00 38.57 ? 266 LYS A NZ    1 
ATOM   2041 N  N     . VAL A 1 267 ? 70.482  105.761 70.909  1.00 40.77 ? 267 VAL A N     1 
ATOM   2042 C  CA    . VAL A 1 267 ? 71.417  104.726 71.337  1.00 40.77 ? 267 VAL A CA    1 
ATOM   2043 C  C     . VAL A 1 267 ? 70.707  103.378 71.368  1.00 40.77 ? 267 VAL A C     1 
ATOM   2044 O  O     . VAL A 1 267 ? 69.485  103.295 71.477  1.00 40.77 ? 267 VAL A O     1 
ATOM   2045 C  CB    . VAL A 1 267 ? 72.036  105.024 72.727  1.00 40.77 ? 267 VAL A CB    1 
ATOM   2046 C  CG1   . VAL A 1 267 ? 72.758  106.364 72.738  1.00 40.77 ? 267 VAL A CG1   1 
ATOM   2047 C  CG2   . VAL A 1 267 ? 70.981  104.973 73.822  1.00 40.77 ? 267 VAL A CG2   1 
ATOM   2048 N  N     . GLU A 1 268 ? 71.496  102.311 71.241  1.00 49.16 ? 268 GLU A N     1 
ATOM   2049 C  CA    . GLU A 1 268 ? 70.952  100.995 70.924  1.00 49.16 ? 268 GLU A CA    1 
ATOM   2050 C  C     . GLU A 1 268 ? 70.460  100.182 72.124  1.00 49.16 ? 268 GLU A C     1 
ATOM   2051 O  O     . GLU A 1 268 ? 69.677  99.248  71.924  1.00 49.16 ? 268 GLU A O     1 
ATOM   2052 C  CB    . GLU A 1 268 ? 71.984  100.189 70.142  1.00 49.16 ? 268 GLU A CB    1 
ATOM   2053 C  CG    . GLU A 1 268 ? 72.366  100.839 68.811  1.00 49.16 ? 268 GLU A CG    1 
ATOM   2054 C  CD    . GLU A 1 268 ? 73.102  99.883  67.886  1.00 49.16 ? 268 GLU A CD    1 
ATOM   2055 O  OE1   . GLU A 1 268 ? 73.799  98.975  68.393  1.00 49.16 ? 268 GLU A OE1   1 
ATOM   2056 O  OE2   . GLU A 1 268 ? 72.972  100.035 66.653  1.00 49.16 ? 268 GLU A OE2   1 
ATOM   2057 N  N     . SER A 1 269 ? 70.874  100.485 73.351  1.00 41.54 ? 269 SER A N     1 
ATOM   2058 C  CA    . SER A 1 269 ? 70.246  99.839  74.497  1.00 41.54 ? 269 SER A CA    1 
ATOM   2059 C  C     . SER A 1 269 ? 70.174  100.819 75.659  1.00 41.54 ? 269 SER A C     1 
ATOM   2060 O  O     . SER A 1 269 ? 70.861  101.839 75.670  1.00 41.54 ? 269 SER A O     1 
ATOM   2061 C  CB    . SER A 1 269 ? 70.969  98.532  74.879  1.00 41.54 ? 269 SER A CB    1 
ATOM   2062 O  OG    . SER A 1 269 ? 72.072  98.741  75.731  1.00 41.54 ? 269 SER A OG    1 
ATOM   2063 N  N     . ASP A 1 270 ? 69.297  100.506 76.622  1.00 39.32 ? 270 ASP A N     1 
ATOM   2064 C  CA    . ASP A 1 270 ? 68.999  101.427 77.722  1.00 39.32 ? 270 ASP A CA    1 
ATOM   2065 C  C     . ASP A 1 270 ? 70.253  101.849 78.475  1.00 39.32 ? 270 ASP A C     1 
ATOM   2066 O  O     . ASP A 1 270 ? 70.410  103.027 78.824  1.00 39.32 ? 270 ASP A O     1 
ATOM   2067 C  CB    . ASP A 1 270 ? 68.031  100.777 78.715  1.00 39.32 ? 270 ASP A CB    1 
ATOM   2068 C  CG    . ASP A 1 270 ? 66.709  100.375 78.092  1.00 39.32 ? 270 ASP A CG    1 
ATOM   2069 O  OD1   . ASP A 1 270 ? 66.392  100.850 76.992  1.00 39.32 ? 270 ASP A OD1   1 
ATOM   2070 O  OD2   . ASP A 1 270 ? 65.985  99.564  78.706  1.00 39.32 ? 270 ASP A OD2   1 
ATOM   2071 N  N     . GLY A 1 271 ? 71.168  100.904 78.707  1.00 32.80 ? 271 GLY A N     1 
ATOM   2072 C  CA    . GLY A 1 271 ? 72.377  101.186 79.459  1.00 32.80 ? 271 GLY A CA    1 
ATOM   2073 C  C     . GLY A 1 271 ? 73.275  102.234 78.844  1.00 32.80 ? 271 GLY A C     1 
ATOM   2074 O  O     . GLY A 1 271 ? 73.979  102.937 79.560  1.00 32.80 ? 271 GLY A O     1 
ATOM   2075 N  N     . HIS A 1 272 ? 73.211  102.410 77.532  1.00 30.69 ? 272 HIS A N     1 
ATOM   2076 C  CA    . HIS A 1 272 ? 73.939  103.508 76.914  1.00 30.69 ? 272 HIS A CA    1 
ATOM   2077 C  C     . HIS A 1 272 ? 73.315  104.861 77.238  1.00 30.69 ? 272 HIS A C     1 
ATOM   2078 O  O     . HIS A 1 272 ? 74.033  105.829 77.511  1.00 30.69 ? 272 HIS A O     1 
ATOM   2079 C  CB    . HIS A 1 272 ? 74.007  103.278 75.407  1.00 30.69 ? 272 HIS A CB    1 
ATOM   2080 C  CG    . HIS A 1 272 ? 75.039  104.107 74.708  1.00 30.69 ? 272 HIS A CG    1 
ATOM   2081 N  ND1   . HIS A 1 272 ? 75.768  105.090 75.340  1.00 30.69 ? 272 HIS A ND1   1 
ATOM   2082 C  CD2   . HIS A 1 272 ? 75.482  104.076 73.430  1.00 30.69 ? 272 HIS A CD2   1 
ATOM   2083 C  CE1   . HIS A 1 272 ? 76.604  105.639 74.478  1.00 30.69 ? 272 HIS A CE1   1 
ATOM   2084 N  NE2   . HIS A 1 272 ? 76.446  105.046 73.310  1.00 30.69 ? 272 HIS A NE2   1 
ATOM   2085 N  N     . ALA A 1 273 ? 71.988  104.952 77.235  1.00 30.36 ? 273 ALA A N     1 
ATOM   2086 C  CA    . ALA A 1 273 ? 71.343  106.188 77.659  1.00 30.36 ? 273 ALA A CA    1 
ATOM   2087 C  C     . ALA A 1 273 ? 71.580  106.463 79.138  1.00 30.36 ? 273 ALA A C     1 
ATOM   2088 O  O     . ALA A 1 273 ? 71.752  107.616 79.539  1.00 30.36 ? 273 ALA A O     1 
ATOM   2089 C  CB    . ALA A 1 273 ? 69.846  106.134 77.359  1.00 30.36 ? 273 ALA A CB    1 
ATOM   2090 N  N     . HIS A 1 274 ? 71.611  105.412 79.956  1.00 26.14 ? 274 HIS A N     1 
ATOM   2091 C  CA    . HIS A 1 274 ? 71.977  105.549 81.363  1.00 26.14 ? 274 HIS A CA    1 
ATOM   2092 C  C     . HIS A 1 274 ? 73.394  106.090 81.542  1.00 26.14 ? 274 HIS A C     1 
ATOM   2093 O  O     . HIS A 1 274 ? 73.598  107.068 82.266  1.00 26.14 ? 274 HIS A O     1 
ATOM   2094 C  CB    . HIS A 1 274 ? 71.791  104.196 82.052  1.00 26.14 ? 274 HIS A CB    1 
ATOM   2095 C  CG    . HIS A 1 274 ? 72.189  104.163 83.497  1.00 26.14 ? 274 HIS A CG    1 
ATOM   2096 N  ND1   . HIS A 1 274 ? 71.764  105.096 84.418  1.00 26.14 ? 274 HIS A ND1   1 
ATOM   2097 C  CD2   . HIS A 1 274 ? 72.914  103.256 84.193  1.00 26.14 ? 274 HIS A CD2   1 
ATOM   2098 C  CE1   . HIS A 1 274 ? 72.244  104.789 85.608  1.00 26.14 ? 274 HIS A CE1   1 
ATOM   2099 N  NE2   . HIS A 1 274 ? 72.945  103.676 85.500  1.00 26.14 ? 274 HIS A NE2   1 
ATOM   2100 N  N     . ASN A 1 275 ? 74.392  105.454 80.924  1.00 23.34 ? 275 ASN A N     1 
ATOM   2101 C  CA    . ASN A 1 275 ? 75.765  105.948 81.031  1.00 23.34 ? 275 ASN A CA    1 
ATOM   2102 C  C     . ASN A 1 275 ? 75.923  107.372 80.502  1.00 23.34 ? 275 ASN A C     1 
ATOM   2103 O  O     . ASN A 1 275 ? 76.646  108.180 81.092  1.00 23.34 ? 275 ASN A O     1 
ATOM   2104 C  CB    . ASN A 1 275 ? 76.739  105.008 80.322  1.00 23.34 ? 275 ASN A CB    1 
ATOM   2105 C  CG    . ASN A 1 275 ? 76.938  103.701 81.057  1.00 23.34 ? 275 ASN A CG    1 
ATOM   2106 O  OD1   . ASN A 1 275 ? 76.638  103.589 82.236  1.00 23.34 ? 275 ASN A OD1   1 
ATOM   2107 N  ND2   . ASN A 1 275 ? 77.487  102.715 80.372  1.00 23.34 ? 275 ASN A ND2   1 
ATOM   2108 N  N     . ARG A 1 276 ? 75.208  107.730 79.443  1.00 25.58 ? 276 ARG A N     1 
ATOM   2109 C  CA    . ARG A 1 276 ? 75.232  109.118 78.985  1.00 25.58 ? 276 ARG A CA    1 
ATOM   2110 C  C     . ARG A 1 276 ? 74.581  110.092 79.968  1.00 25.58 ? 276 ARG A C     1 
ATOM   2111 O  O     . ARG A 1 276 ? 75.123  111.173 80.220  1.00 25.58 ? 276 ARG A O     1 
ATOM   2112 C  CB    . ARG A 1 276 ? 74.578  109.211 77.611  1.00 25.58 ? 276 ARG A CB    1 
ATOM   2113 C  CG    . ARG A 1 276 ? 75.438  108.633 76.509  1.00 25.58 ? 276 ARG A CG    1 
ATOM   2114 C  CD    . ARG A 1 276 ? 74.814  108.835 75.160  1.00 25.58 ? 276 ARG A CD    1 
ATOM   2115 N  NE    . ARG A 1 276 ? 75.755  108.546 74.090  1.00 25.58 ? 276 ARG A NE    1 
ATOM   2116 C  CZ    . ARG A 1 276 ? 75.576  108.895 72.825  1.00 25.58 ? 276 ARG A CZ    1 
ATOM   2117 N  NH1   . ARG A 1 276 ? 74.473  109.498 72.426  1.00 25.58 ? 276 ARG A NH1   1 
ATOM   2118 N  NH2   . ARG A 1 276 ? 76.533  108.640 71.940  1.00 25.58 ? 276 ARG A NH2   1 
ATOM   2119 N  N     . ALA A 1 277 ? 73.426  109.740 80.530  1.00 23.17 ? 277 ALA A N     1 
ATOM   2120 C  CA    . ALA A 1 277 ? 72.810  110.572 81.557  1.00 23.17 ? 277 ALA A CA    1 
ATOM   2121 C  C     . ALA A 1 277 ? 73.693  110.733 82.794  1.00 23.17 ? 277 ALA A C     1 
ATOM   2122 O  O     . ALA A 1 277 ? 73.812  111.840 83.337  1.00 23.17 ? 277 ALA A O     1 
ATOM   2123 C  CB    . ALA A 1 277 ? 71.455  109.987 81.941  1.00 23.17 ? 277 ALA A CB    1 
ATOM   2124 N  N     . VAL A 1 278 ? 74.295  109.641 83.271  1.00 20.92 ? 278 VAL A N     1 
ATOM   2125 C  CA    . VAL A 1 278 ? 75.222  109.708 84.402  1.00 20.92 ? 278 VAL A CA    1 
ATOM   2126 C  C     . VAL A 1 278 ? 76.372  110.654 84.106  1.00 20.92 ? 278 VAL A C     1 
ATOM   2127 O  O     . VAL A 1 278 ? 76.723  111.509 84.925  1.00 20.92 ? 278 VAL A O     1 
ATOM   2128 C  CB    . VAL A 1 278 ? 75.738  108.306 84.758  1.00 20.92 ? 278 VAL A CB    1 
ATOM   2129 C  CG1   . VAL A 1 278 ? 76.916  108.411 85.681  1.00 20.92 ? 278 VAL A CG1   1 
ATOM   2130 C  CG2   . VAL A 1 278 ? 74.649  107.501 85.422  1.00 20.92 ? 278 VAL A CG2   1 
ATOM   2131 N  N     . ARG A 1 279 ? 76.996  110.489 82.945  1.00 20.71 ? 279 ARG A N     1 
ATOM   2132 C  CA    . ARG A 1 279 ? 78.070  111.378 82.534  1.00 20.71 ? 279 ARG A CA    1 
ATOM   2133 C  C     . ARG A 1 279 ? 77.625  112.832 82.521  1.00 20.71 ? 279 ARG A C     1 
ATOM   2134 O  O     . ARG A 1 279 ? 78.344  113.711 83.004  1.00 20.71 ? 279 ARG A O     1 
ATOM   2135 C  CB    . ARG A 1 279 ? 78.577  110.925 81.169  1.00 20.71 ? 279 ARG A CB    1 
ATOM   2136 C  CG    . ARG A 1 279 ? 79.778  111.644 80.636  1.00 20.71 ? 279 ARG A CG    1 
ATOM   2137 C  CD    . ARG A 1 279 ? 80.088  111.185 79.226  1.00 20.71 ? 279 ARG A CD    1 
ATOM   2138 N  NE    . ARG A 1 279 ? 81.265  111.828 78.665  1.00 20.71 ? 279 ARG A NE    1 
ATOM   2139 C  CZ    . ARG A 1 279 ? 82.515  111.411 78.788  1.00 20.71 ? 279 ARG A CZ    1 
ATOM   2140 N  NH1   . ARG A 1 279 ? 82.821  110.316 79.454  1.00 20.71 ? 279 ARG A NH1   1 
ATOM   2141 N  NH2   . ARG A 1 279 ? 83.487  112.123 78.231  1.00 20.71 ? 279 ARG A NH2   1 
ATOM   2142 N  N     . LYS A 1 280 ? 76.440  113.107 81.970  1.00 23.70 ? 280 LYS A N     1 
ATOM   2143 C  CA    . LYS A 1 280 ? 75.905  114.470 81.931  1.00 23.70 ? 280 LYS A CA    1 
ATOM   2144 C  C     . LYS A 1 280 ? 75.740  115.076 83.325  1.00 23.70 ? 280 LYS A C     1 
ATOM   2145 O  O     . LYS A 1 280 ? 76.152  116.217 83.578  1.00 23.70 ? 280 LYS A O     1 
ATOM   2146 C  CB    . LYS A 1 280 ? 74.566  114.452 81.197  1.00 23.70 ? 280 LYS A CB    1 
ATOM   2147 C  CG    . LYS A 1 280 ? 73.858  115.789 81.075  1.00 23.70 ? 280 LYS A CG    1 
ATOM   2148 C  CD    . LYS A 1 280 ? 74.696  116.849 80.401  1.00 23.70 ? 280 LYS A CD    1 
ATOM   2149 C  CE    . LYS A 1 280 ? 73.864  118.082 80.104  1.00 23.70 ? 280 LYS A CE    1 
ATOM   2150 N  NZ    . LYS A 1 280 ? 74.657  119.167 79.487  1.00 23.70 ? 280 LYS A NZ    1 
ATOM   2151 N  N     . VAL A 1 281 ? 75.175  114.312 84.257  1.00 20.96 ? 281 VAL A N     1 
ATOM   2152 C  CA    . VAL A 1 281 ? 74.986  114.817 85.615  1.00 20.96 ? 281 VAL A CA    1 
ATOM   2153 C  C     . VAL A 1 281 ? 76.313  114.999 86.347  1.00 20.96 ? 281 VAL A C     1 
ATOM   2154 O  O     . VAL A 1 281 ? 76.501  115.985 87.062  1.00 20.96 ? 281 VAL A O     1 
ATOM   2155 C  CB    . VAL A 1 281 ? 74.043  113.890 86.398  1.00 20.96 ? 281 VAL A CB    1 
ATOM   2156 C  CG1   . VAL A 1 281 ? 73.821  114.431 87.775  1.00 20.96 ? 281 VAL A CG1   1 
ATOM   2157 C  CG2   . VAL A 1 281 ? 72.739  113.736 85.678  1.00 20.96 ? 281 VAL A CG2   1 
ATOM   2158 N  N     . ALA A 1 282 ? 77.235  114.038 86.223  1.00 20.40 ? 282 ALA A N     1 
ATOM   2159 C  CA    . ALA A 1 282 ? 78.558  114.169 86.833  1.00 20.40 ? 282 ALA A CA    1 
ATOM   2160 C  C     . ALA A 1 282 ? 79.300  115.403 86.344  1.00 20.40 ? 282 ALA A C     1 
ATOM   2161 O  O     . ALA A 1 282 ? 79.876  116.150 87.141  1.00 20.40 ? 282 ALA A O     1 
ATOM   2162 C  CB    . ALA A 1 282 ? 79.381  112.912 86.577  1.00 20.40 ? 282 ALA A CB    1 
ATOM   2163 N  N     . LYS A 1 283 ? 79.276  115.648 85.037  1.00 21.23 ? 283 LYS A N     1 
ATOM   2164 C  CA    . LYS A 1 283 ? 79.828  116.884 84.495  1.00 21.23 ? 283 LYS A CA    1 
ATOM   2165 C  C     . LYS A 1 283 ? 79.155  118.141 85.051  1.00 21.23 ? 283 LYS A C     1 
ATOM   2166 O  O     . LYS A 1 283 ? 79.840  119.120 85.377  1.00 21.23 ? 283 LYS A O     1 
ATOM   2167 C  CB    . LYS A 1 283 ? 79.759  116.851 82.972  1.00 21.23 ? 283 LYS A CB    1 
ATOM   2168 C  CG    . LYS A 1 283 ? 80.752  115.875 82.366  1.00 21.23 ? 283 LYS A CG    1 
ATOM   2169 C  CD    . LYS A 1 283 ? 80.747  115.870 80.865  1.00 21.23 ? 283 LYS A CD    1 
ATOM   2170 C  CE    . LYS A 1 283 ? 81.332  117.148 80.313  1.00 21.23 ? 283 LYS A CE    1 
ATOM   2171 N  NZ    . LYS A 1 283 ? 81.677  116.997 78.883  1.00 21.23 ? 283 LYS A NZ    1 
ATOM   2172 N  N     . VAL A 1 284 ? 77.824  118.162 85.154  1.00 26.34 ? 284 VAL A N     1 
ATOM   2173 C  CA    . VAL A 1 284 ? 77.174  119.382 85.649  1.00 26.34 ? 284 VAL A CA    1 
ATOM   2174 C  C     . VAL A 1 284 ? 77.428  119.583 87.140  1.00 26.34 ? 284 VAL A C     1 
ATOM   2175 O  O     . VAL A 1 284 ? 77.615  120.713 87.608  1.00 26.34 ? 284 VAL A O     1 
ATOM   2176 C  CB    . VAL A 1 284 ? 75.670  119.365 85.314  1.00 26.34 ? 284 VAL A CB    1 
ATOM   2177 C  CG1   . VAL A 1 284 ? 74.937  120.507 86.005  1.00 26.34 ? 284 VAL A CG1   1 
ATOM   2178 C  CG2   . VAL A 1 284 ? 75.486  119.485 83.821  1.00 26.34 ? 284 VAL A CG2   1 
ATOM   2179 N  N     . PHE A 1 285 ? 77.493  118.498 87.898  1.00 24.38 ? 285 PHE A N     1 
ATOM   2180 C  CA    . PHE A 1 285 ? 77.889  118.588 89.295  1.00 24.38 ? 285 PHE A CA    1 
ATOM   2181 C  C     . PHE A 1 285 ? 79.299  119.135 89.464  1.00 24.38 ? 285 PHE A C     1 
ATOM   2182 O  O     . PHE A 1 285 ? 79.538  119.956 90.352  1.00 24.38 ? 285 PHE A O     1 
ATOM   2183 C  CB    . PHE A 1 285 ? 77.766  117.223 89.963  1.00 24.38 ? 285 PHE A CB    1 
ATOM   2184 C  CG    . PHE A 1 285 ? 78.169  117.228 91.393  1.00 24.38 ? 285 PHE A CG    1 
ATOM   2185 C  CD1   . PHE A 1 285 ? 77.434  117.931 92.324  1.00 24.38 ? 285 PHE A CD1   1 
ATOM   2186 C  CD2   . PHE A 1 285 ? 79.283  116.530 91.816  1.00 24.38 ? 285 PHE A CD2   1 
ATOM   2187 C  CE1   . PHE A 1 285 ? 77.803  117.957 93.639  1.00 24.38 ? 285 PHE A CE1   1 
ATOM   2188 C  CE2   . PHE A 1 285 ? 79.655  116.544 93.138  1.00 24.38 ? 285 PHE A CE2   1 
ATOM   2189 C  CZ    . PHE A 1 285 ? 78.912  117.263 94.050  1.00 24.38 ? 285 PHE A CZ    1 
ATOM   2190 N  N     . LEU A 1 286 ? 80.254  118.678 88.651  1.00 24.96 ? 286 LEU A N     1 
ATOM   2191 C  CA    . LEU A 1 286 ? 81.598  119.251 88.703  1.00 24.96 ? 286 LEU A CA    1 
ATOM   2192 C  C     . LEU A 1 286 ? 81.616  120.718 88.309  1.00 24.96 ? 286 LEU A C     1 
ATOM   2193 O  O     . LEU A 1 286 ? 82.369  121.505 88.888  1.00 24.96 ? 286 LEU A O     1 
ATOM   2194 C  CB    . LEU A 1 286 ? 82.550  118.452 87.819  1.00 24.96 ? 286 LEU A CB    1 
ATOM   2195 C  CG    . LEU A 1 286 ? 82.930  117.050 88.293  1.00 24.96 ? 286 LEU A CG    1 
ATOM   2196 C  CD1   . LEU A 1 286 ? 83.784  116.373 87.260  1.00 24.96 ? 286 LEU A CD1   1 
ATOM   2197 C  CD2   . LEU A 1 286 ? 83.665  117.099 89.608  1.00 24.96 ? 286 LEU A CD2   1 
ATOM   2198 N  N     . GLN A 1 287 ? 80.780  121.119 87.352  1.00 30.29 ? 287 GLN A N     1 
ATOM   2199 C  CA    . GLN A 1 287 ? 80.615  122.548 87.084  1.00 30.29 ? 287 GLN A CA    1 
ATOM   2200 C  C     . GLN A 1 287 ? 80.146  123.323 88.323  1.00 30.29 ? 287 GLN A C     1 
ATOM   2201 O  O     . GLN A 1 287 ? 80.662  124.408 88.619  1.00 30.29 ? 287 GLN A O     1 
ATOM   2202 C  CB    . GLN A 1 287 ? 79.657  122.749 85.909  1.00 30.29 ? 287 GLN A CB    1 
ATOM   2203 C  CG    . GLN A 1 287 ? 79.420  124.209 85.531  1.00 30.29 ? 287 GLN A CG    1 
ATOM   2204 C  CD    . GLN A 1 287 ? 78.002  124.486 85.047  1.00 30.29 ? 287 GLN A CD    1 
ATOM   2205 O  OE1   . GLN A 1 287 ? 77.333  123.612 84.494  1.00 30.29 ? 287 GLN A OE1   1 
ATOM   2206 N  NE2   . GLN A 1 287 ? 77.536  125.706 85.266  1.00 30.29 ? 287 GLN A NE2   1 
ATOM   2207 N  N     . HIS A 1 288 ? 79.194  122.768 89.077  1.00 35.47 ? 288 HIS A N     1 
ATOM   2208 C  CA    . HIS A 1 288 ? 78.725  123.437 90.297  1.00 35.47 ? 288 HIS A CA    1 
ATOM   2209 C  C     . HIS A 1 288 ? 79.760  123.422 91.423  1.00 35.47 ? 288 HIS A C     1 
ATOM   2210 O  O     . HIS A 1 288 ? 79.899  124.413 92.150  1.00 35.47 ? 288 HIS A O     1 
ATOM   2211 C  CB    . HIS A 1 288 ? 77.402  122.830 90.764  1.00 35.47 ? 288 HIS A CB    1 
ATOM   2212 C  CG    . HIS A 1 288 ? 76.281  123.012 89.789  1.00 35.47 ? 288 HIS A CG    1 
ATOM   2213 N  ND1   . HIS A 1 288 ? 75.062  122.384 89.925  1.00 35.47 ? 288 HIS A ND1   1 
ATOM   2214 C  CD2   . HIS A 1 288 ? 76.185  123.780 88.680  1.00 35.47 ? 288 HIS A CD2   1 
ATOM   2215 C  CE1   . HIS A 1 288 ? 74.271  122.747 88.933  1.00 35.47 ? 288 HIS A CE1   1 
ATOM   2216 N  NE2   . HIS A 1 288 ? 74.929  123.590 88.161  1.00 35.47 ? 288 HIS A NE2   1 
ATOM   2217 N  N     . TYR A 1 289 ? 80.492  122.322 91.591  1.00 31.05 ? 289 TYR A N     1 
ATOM   2218 C  CA    . TYR A 1 289 ? 81.584  122.306 92.561  1.00 31.05 ? 289 TYR A CA    1 
ATOM   2219 C  C     . TYR A 1 289 ? 82.635  123.357 92.234  1.00 31.05 ? 289 TYR A C     1 
ATOM   2220 O  O     . TYR A 1 289 ? 83.083  124.099 93.117  1.00 31.05 ? 289 TYR A O     1 
ATOM   2221 C  CB    . TYR A 1 289 ? 82.238  120.924 92.607  1.00 31.05 ? 289 TYR A CB    1 
ATOM   2222 C  CG    . TYR A 1 289 ? 83.442  120.860 93.524  1.00 31.05 ? 289 TYR A CG    1 
ATOM   2223 C  CD1   . TYR A 1 289 ? 83.313  120.555 94.867  1.00 31.05 ? 289 TYR A CD1   1 
ATOM   2224 C  CD2   . TYR A 1 289 ? 84.709  121.163 93.051  1.00 31.05 ? 289 TYR A CD2   1 
ATOM   2225 C  CE1   . TYR A 1 289 ? 84.423  120.501 95.699  1.00 31.05 ? 289 TYR A CE1   1 
ATOM   2226 C  CE2   . TYR A 1 289 ? 85.803  121.144 93.872  1.00 31.05 ? 289 TYR A CE2   1 
ATOM   2227 C  CZ    . TYR A 1 289 ? 85.665  120.808 95.193  1.00 31.05 ? 289 TYR A CZ    1 
ATOM   2228 O  OH    . TYR A 1 289 ? 86.779  120.791 96.000  1.00 31.05 ? 289 TYR A OH    1 
ATOM   2229 N  N     . TRP A 1 290 ? 82.970  123.497 90.958  1.00 36.01 ? 290 TRP A N     1 
ATOM   2230 C  CA    . TRP A 1 290 ? 83.863  124.560 90.533  1.00 36.01 ? 290 TRP A CA    1 
ATOM   2231 C  C     . TRP A 1 290 ? 83.302  125.928 90.891  1.00 36.01 ? 290 TRP A C     1 
ATOM   2232 O  O     . TRP A 1 290 ? 83.982  126.724 91.543  1.00 36.01 ? 290 TRP A O     1 
ATOM   2233 C  CB    . TRP A 1 290 ? 84.138  124.416 89.035  1.00 36.01 ? 290 TRP A CB    1 
ATOM   2234 C  CG    . TRP A 1 290 ? 85.215  125.302 88.469  1.00 36.01 ? 290 TRP A CG    1 
ATOM   2235 C  CD1   . TRP A 1 290 ? 86.536  125.001 88.366  1.00 36.01 ? 290 TRP A CD1   1 
ATOM   2236 C  CD2   . TRP A 1 290 ? 85.046  126.562 87.815  1.00 36.01 ? 290 TRP A CD2   1 
ATOM   2237 N  NE1   . TRP A 1 290 ? 87.210  126.019 87.754  1.00 36.01 ? 290 TRP A NE1   1 
ATOM   2238 C  CE2   . TRP A 1 290 ? 86.317  126.992 87.405  1.00 36.01 ? 290 TRP A CE2   1 
ATOM   2239 C  CE3   . TRP A 1 290 ? 83.949  127.384 87.570  1.00 36.01 ? 290 TRP A CE3   1 
ATOM   2240 C  CZ2   . TRP A 1 290 ? 86.522  128.202 86.755  1.00 36.01 ? 290 TRP A CZ2   1 
ATOM   2241 C  CZ3   . TRP A 1 290 ? 84.155  128.588 86.929  1.00 36.01 ? 290 TRP A CZ3   1 
ATOM   2242 C  CH2   . TRP A 1 290 ? 85.430  128.986 86.530  1.00 36.01 ? 290 TRP A CH2   1 
ATOM   2243 N  N     . VAL A 1 291 ? 82.084  126.241 90.436  1.00 39.77 ? 291 VAL A N     1 
ATOM   2244 C  CA    . VAL A 1 291 ? 81.498  127.568 90.675  1.00 39.77 ? 291 VAL A CA    1 
ATOM   2245 C  C     . VAL A 1 291 ? 81.484  127.938 92.159  1.00 39.77 ? 291 VAL A C     1 
ATOM   2246 O  O     . VAL A 1 291 ? 81.951  129.017 92.555  1.00 39.77 ? 291 VAL A O     1 
ATOM   2247 C  CB    . VAL A 1 291 ? 80.086  127.647 90.066  1.00 39.77 ? 291 VAL A CB    1 
ATOM   2248 C  CG1   . VAL A 1 291 ? 79.333  128.835 90.615  1.00 39.77 ? 291 VAL A CG1   1 
ATOM   2249 C  CG2   . VAL A 1 291 ? 80.172  127.778 88.556  1.00 39.77 ? 291 VAL A CG2   1 
ATOM   2250 N  N     . VAL A 1 292 ? 80.965  127.045 93.003  1.00 42.88 ? 292 VAL A N     1 
ATOM   2251 C  CA    . VAL A 1 292 ? 80.917  127.308 94.442  1.00 42.88 ? 292 VAL A CA    1 
ATOM   2252 C  C     . VAL A 1 292 ? 82.311  127.500 95.036  1.00 42.88 ? 292 VAL A C     1 
ATOM   2253 O  O     . VAL A 1 292 ? 82.525  128.419 95.835  1.00 42.88 ? 292 VAL A O     1 
ATOM   2254 C  CB    . VAL A 1 292 ? 80.148  126.182 95.155  1.00 42.88 ? 292 VAL A CB    1 
ATOM   2255 C  CG1   . VAL A 1 292 ? 80.176  126.357 96.661  1.00 42.88 ? 292 VAL A CG1   1 
ATOM   2256 C  CG2   . VAL A 1 292 ? 78.731  126.124 94.659  1.00 42.88 ? 292 VAL A CG2   1 
ATOM   2257 N  N     . SER A 1 293 ? 83.284  126.660 94.666  1.00 42.38 ? 293 SER A N     1 
ATOM   2258 C  CA    . SER A 1 293 ? 84.614  126.810 95.266  1.00 42.38 ? 293 SER A CA    1 
ATOM   2259 C  C     . SER A 1 293 ? 85.316  128.087 94.812  1.00 42.38 ? 293 SER A C     1 
ATOM   2260 O  O     . SER A 1 293 ? 85.991  128.752 95.609  1.00 42.38 ? 293 SER A O     1 
ATOM   2261 C  CB    . SER A 1 293 ? 85.473  125.592 94.969  1.00 42.38 ? 293 SER A CB    1 
ATOM   2262 O  OG    . SER A 1 293 ? 84.822  124.425 95.420  1.00 42.38 ? 293 SER A OG    1 
ATOM   2263 N  N     . ARG A 1 294 ? 85.152  128.453 93.545  1.00 50.51 ? 294 ARG A N     1 
ATOM   2264 C  CA    . ARG A 1 294 ? 85.718  129.699 93.056  1.00 50.51 ? 294 ARG A CA    1 
ATOM   2265 C  C     . ARG A 1 294 ? 85.140  130.886 93.806  1.00 50.51 ? 294 ARG A C     1 
ATOM   2266 O  O     . ARG A 1 294 ? 85.875  131.802 94.195  1.00 50.51 ? 294 ARG A O     1 
ATOM   2267 C  CB    . ARG A 1 294 ? 85.440  129.849 91.557  1.00 50.51 ? 294 ARG A CB    1 
ATOM   2268 C  CG    . ARG A 1 294 ? 86.052  128.788 90.637  1.00 50.51 ? 294 ARG A CG    1 
ATOM   2269 C  CD    . ARG A 1 294 ? 87.545  128.919 90.428  1.00 50.51 ? 294 ARG A CD    1 
ATOM   2270 N  NE    . ARG A 1 294 ? 87.879  130.030 89.549  1.00 50.51 ? 294 ARG A NE    1 
ATOM   2271 C  CZ    . ARG A 1 294 ? 89.074  130.238 89.015  1.00 50.51 ? 294 ARG A CZ    1 
ATOM   2272 N  NH1   . ARG A 1 294 ? 90.097  129.451 89.287  1.00 50.51 ? 294 ARG A NH1   1 
ATOM   2273 N  NH2   . ARG A 1 294 ? 89.248  131.269 88.192  1.00 50.51 ? 294 ARG A NH2   1 
ATOM   2274 N  N     . GLU A 1 295 ? 83.824  130.892 94.023  1.00 58.35 ? 295 GLU A N     1 
ATOM   2275 C  CA    . GLU A 1 295 ? 83.220  132.000 94.763  1.00 58.35 ? 295 GLU A CA    1 
ATOM   2276 C  C     . GLU A 1 295 ? 83.642  132.019 96.228  1.00 58.35 ? 295 GLU A C     1 
ATOM   2277 O  O     . GLU A 1 295 ? 83.856  133.097 96.794  1.00 58.35 ? 295 GLU A O     1 
ATOM   2278 C  CB    . GLU A 1 295 ? 81.703  131.953 94.630  1.00 58.35 ? 295 GLU A CB    1 
ATOM   2279 C  CG    . GLU A 1 295 ? 81.260  132.316 93.224  1.00 58.35 ? 295 GLU A CG    1 
ATOM   2280 C  CD    . GLU A 1 295 ? 79.761  132.318 93.044  1.00 58.35 ? 295 GLU A CD    1 
ATOM   2281 O  OE1   . GLU A 1 295 ? 79.037  132.461 94.045  1.00 58.35 ? 295 GLU A OE1   1 
ATOM   2282 O  OE2   . GLU A 1 295 ? 79.303  132.176 91.892  1.00 58.35 ? 295 GLU A OE2   1 
ATOM   2283 N  N     . LEU A 1 296 ? 83.778  130.847 96.853  1.00 53.60 ? 296 LEU A N     1 
ATOM   2284 C  CA    . LEU A 1 296 ? 84.261  130.780 98.231  1.00 53.60 ? 296 LEU A CA    1 
ATOM   2285 C  C     . LEU A 1 296 ? 85.665  131.352 98.385  1.00 53.60 ? 296 LEU A C     1 
ATOM   2286 O  O     . LEU A 1 296 ? 85.910  132.189 99.259  1.00 53.60 ? 296 LEU A O     1 
ATOM   2287 C  CB    . LEU A 1 296 ? 84.243  129.335 98.723  1.00 53.60 ? 296 LEU A CB    1 
ATOM   2288 C  CG    . LEU A 1 296 ? 82.937  128.720 99.209  1.00 53.60 ? 296 LEU A CG    1 
ATOM   2289 C  CD1   . LEU A 1 296 ? 83.120  127.237 99.356  1.00 53.60 ? 296 LEU A CD1   1 
ATOM   2290 C  CD2   . LEU A 1 296 ? 82.531  129.325 100.525 1.00 53.60 ? 296 LEU A CD2   1 
ATOM   2291 N  N     . ALA A 1 297 ? 86.607  130.901 97.563  1.00 60.37 ? 297 ALA A N     1 
ATOM   2292 C  CA    . ALA A 1 297 ? 88.004  131.282 97.742  1.00 60.37 ? 297 ALA A CA    1 
ATOM   2293 C  C     . ALA A 1 297 ? 88.340  132.650 97.163  1.00 60.37 ? 297 ALA A C     1 
ATOM   2294 O  O     . ALA A 1 297 ? 89.422  133.175 97.450  1.00 60.37 ? 297 ALA A O     1 
ATOM   2295 C  CB    . ALA A 1 297 ? 88.929  130.229 97.133  1.00 60.37 ? 297 ALA A CB    1 
ATOM   2296 N  N     . GLY A 1 298 ? 87.452  133.238 96.372  1.00 64.33 ? 298 GLY A N     1 
ATOM   2297 C  CA    . GLY A 1 298 ? 87.712  134.536 95.785  1.00 64.33 ? 298 GLY A CA    1 
ATOM   2298 C  C     . GLY A 1 298 ? 88.517  134.500 94.508  1.00 64.33 ? 298 GLY A C     1 
ATOM   2299 O  O     . GLY A 1 298 ? 89.358  135.377 94.279  1.00 64.33 ? 298 GLY A O     1 
ATOM   2300 N  N     . PHE A 1 299 ? 88.295  133.492 93.679  1.00 64.26 ? 299 PHE A N     1 
ATOM   2301 C  CA    . PHE A 1 299 ? 88.857  133.391 92.343  1.00 64.26 ? 299 PHE A CA    1 
ATOM   2302 C  C     . PHE A 1 299 ? 87.821  133.818 91.308  1.00 64.26 ? 299 PHE A C     1 
ATOM   2303 O  O     . PHE A 1 299 ? 86.639  133.995 91.609  1.00 64.26 ? 299 PHE A O     1 
ATOM   2304 C  CB    . PHE A 1 299 ? 89.388  131.979 92.086  1.00 64.26 ? 299 PHE A CB    1 
ATOM   2305 C  CG    . PHE A 1 299 ? 90.455  131.567 93.061  1.00 64.26 ? 299 PHE A CG    1 
ATOM   2306 C  CD1   . PHE A 1 299 ? 91.541  132.405 93.301  1.00 64.26 ? 299 PHE A CD1   1 
ATOM   2307 C  CD2   . PHE A 1 299 ? 90.382  130.363 93.733  1.00 64.26 ? 299 PHE A CD2   1 
ATOM   2308 C  CE1   . PHE A 1 299 ? 92.528  132.048 94.200  1.00 64.26 ? 299 PHE A CE1   1 
ATOM   2309 C  CE2   . PHE A 1 299 ? 91.365  130.000 94.623  1.00 64.26 ? 299 PHE A CE2   1 
ATOM   2310 C  CZ    . PHE A 1 299 ? 92.439  130.843 94.862  1.00 64.26 ? 299 PHE A CZ    1 
ATOM   2311 N  N     . SER A 1 300 ? 88.286  133.997 90.075  1.00 69.99 ? 300 SER A N     1 
ATOM   2312 C  CA    . SER A 1 300 ? 87.437  134.537 89.021  1.00 69.99 ? 300 SER A CA    1 
ATOM   2313 C  C     . SER A 1 300 ? 86.313  133.580 88.623  1.00 69.99 ? 300 SER A C     1 
ATOM   2314 O  O     . SER A 1 300 ? 86.493  132.360 88.560  1.00 69.99 ? 300 SER A O     1 
ATOM   2315 C  CB    . SER A 1 300 ? 88.295  134.871 87.797  1.00 69.99 ? 300 SER A CB    1 
ATOM   2316 O  OG    . SER A 1 300 ? 87.557  135.587 86.826  1.00 69.99 ? 300 SER A OG    1 
ATOM   2317 N  N     . VAL A 1 301 ? 85.144  134.161 88.378  1.00 70.21 ? 301 VAL A N     1 
ATOM   2318 C  CA    . VAL A 1 301 ? 83.997  133.472 87.801  1.00 70.21 ? 301 VAL A CA    1 
ATOM   2319 C  C     . VAL A 1 301 ? 83.952  133.730 86.298  1.00 70.21 ? 301 VAL A C     1 
ATOM   2320 O  O     . VAL A 1 301 ? 84.666  134.577 85.769  1.00 70.21 ? 301 VAL A O     1 
ATOM   2321 C  CB    . VAL A 1 301 ? 82.671  133.879 88.491  1.00 70.21 ? 301 VAL A CB    1 
ATOM   2322 C  CG1   . VAL A 1 301 ? 82.684  133.451 89.947  1.00 70.21 ? 301 VAL A CG1   1 
ATOM   2323 C  CG2   . VAL A 1 301 ? 82.444  135.380 88.382  1.00 70.21 ? 301 VAL A CG2   1 
ATOM   2324 N  N     . SER A 1 302 ? 83.119  132.970 85.591  1.00 65.76 ? 302 SER A N     1 
ATOM   2325 C  CA    . SER A 1 302 ? 83.036  133.089 84.132  1.00 65.76 ? 302 SER A CA    1 
ATOM   2326 C  C     . SER A 1 302 ? 81.704  132.607 83.572  1.00 65.76 ? 302 SER A C     1 
ATOM   2327 O  O     . SER A 1 302 ? 80.638  132.954 84.083  1.00 65.76 ? 302 SER A O     1 
ATOM   2328 C  CB    . SER A 1 302 ? 84.174  132.301 83.474  1.00 65.76 ? 302 SER A CB    1 
ATOM   2329 O  OG    . SER A 1 302 ? 84.098  132.352 82.060  1.00 65.76 ? 302 SER A OG    1 
ATOM   2330 N  N     . LYS A 1 317 ? 72.160  126.162 87.789  1.00 60.86 ? 317 LYS A N     1 
ATOM   2331 C  CA    . LYS A 1 317 ? 72.528  126.734 89.082  1.00 60.86 ? 317 LYS A CA    1 
ATOM   2332 C  C     . LYS A 1 317 ? 72.684  125.647 90.131  1.00 60.86 ? 317 LYS A C     1 
ATOM   2333 O  O     . LYS A 1 317 ? 71.918  124.684 90.138  1.00 60.86 ? 317 LYS A O     1 
ATOM   2334 C  CB    . LYS A 1 317 ? 71.483  127.753 89.529  1.00 60.86 ? 317 LYS A CB    1 
ATOM   2335 C  CG    . LYS A 1 317 ? 71.808  129.180 89.138  1.00 60.86 ? 317 LYS A CG    1 
ATOM   2336 C  CD    . LYS A 1 317 ? 72.720  129.861 90.152  1.00 60.86 ? 317 LYS A CD    1 
ATOM   2337 C  CE    . LYS A 1 317 ? 72.019  130.024 91.490  1.00 60.86 ? 317 LYS A CE    1 
ATOM   2338 N  NZ    . LYS A 1 317 ? 72.792  130.902 92.414  1.00 60.86 ? 317 LYS A NZ    1 
ATOM   2339 N  N     . PRO A 1 318 ? 73.670  125.791 91.015  1.00 56.97 ? 318 PRO A N     1 
ATOM   2340 C  CA    . PRO A 1 318 ? 73.690  124.964 92.212  1.00 56.97 ? 318 PRO A CA    1 
ATOM   2341 C  C     . PRO A 1 318 ? 72.422  125.164 93.014  1.00 56.97 ? 318 PRO A C     1 
ATOM   2342 O  O     . PRO A 1 318 ? 71.802  126.243 92.972  1.00 56.97 ? 318 PRO A O     1 
ATOM   2343 C  CB    . PRO A 1 318 ? 74.929  125.463 92.971  1.00 56.97 ? 318 PRO A CB    1 
ATOM   2344 C  CG    . PRO A 1 318 ? 75.714  126.249 92.002  1.00 56.97 ? 318 PRO A CG    1 
ATOM   2345 C  CD    . PRO A 1 318 ? 74.738  126.798 91.022  1.00 56.97 ? 318 PRO A CD    1 
ATOM   2346 N  N     . PRO A 1 319 ? 71.989  124.146 93.751  1.00 61.37 ? 319 PRO A N     1 
ATOM   2347 C  CA    . PRO A 1 319 ? 70.685  124.219 94.423  1.00 61.37 ? 319 PRO A CA    1 
ATOM   2348 C  C     . PRO A 1 319 ? 70.619  125.183 95.603  1.00 61.37 ? 319 PRO A C     1 
ATOM   2349 O  O     . PRO A 1 319 ? 69.816  126.119 95.601  1.00 61.37 ? 319 PRO A O     1 
ATOM   2350 C  CB    . PRO A 1 319 ? 70.444  122.769 94.868  1.00 61.37 ? 319 PRO A CB    1 
ATOM   2351 C  CG    . PRO A 1 319 ? 71.781  122.134 94.897  1.00 61.37 ? 319 PRO A CG    1 
ATOM   2352 C  CD    . PRO A 1 319 ? 72.570  122.801 93.815  1.00 61.37 ? 319 PRO A CD    1 
ATOM   2353 N  N     . HIS A 1 320 ? 71.459  124.963 96.612  1.00 66.70 ? 320 HIS A N     1 
ATOM   2354 C  CA    . HIS A 1 320 ? 71.412  125.726 97.853  1.00 66.70 ? 320 HIS A CA    1 
ATOM   2355 C  C     . HIS A 1 320 ? 72.198  127.032 97.813  1.00 66.70 ? 320 HIS A C     1 
ATOM   2356 O  O     . HIS A 1 320 ? 71.981  127.894 98.671  1.00 66.70 ? 320 HIS A O     1 
ATOM   2357 C  CB    . HIS A 1 320 ? 71.931  124.853 98.998  1.00 66.70 ? 320 HIS A CB    1 
ATOM   2358 C  CG    . HIS A 1 320 ? 71.058  123.671 99.296  1.00 66.70 ? 320 HIS A CG    1 
ATOM   2359 N  ND1   . HIS A 1 320 ? 69.854  123.779 99.958  1.00 66.70 ? 320 HIS A ND1   1 
ATOM   2360 C  CD2   . HIS A 1 320 ? 71.201  122.360 98.989  1.00 66.70 ? 320 HIS A CD2   1 
ATOM   2361 C  CE1   . HIS A 1 320 ? 69.303  122.583 100.064 1.00 66.70 ? 320 HIS A CE1   1 
ATOM   2362 N  NE2   . HIS A 1 320 ? 70.099  121.705 99.482  1.00 66.70 ? 320 HIS A NE2   1 
ATOM   2363 N  N     . TRP A 1 321 ? 73.101  127.199 96.856  1.00 70.66 ? 321 TRP A N     1 
ATOM   2364 C  CA    . TRP A 1 321 ? 74.063  128.292 96.891  1.00 70.66 ? 321 TRP A CA    1 
ATOM   2365 C  C     . TRP A 1 321 ? 73.471  129.590 96.356  1.00 70.66 ? 321 TRP A C     1 
ATOM   2366 O  O     . TRP A 1 321 ? 73.086  129.673 95.185  1.00 70.66 ? 321 TRP A O     1 
ATOM   2367 C  CB    . TRP A 1 321 ? 75.314  127.908 96.108  1.00 70.66 ? 321 TRP A CB    1 
ATOM   2368 C  CG    . TRP A 1 321 ? 76.416  128.911 96.180  1.00 70.66 ? 321 TRP A CG    1 
ATOM   2369 C  CD1   . TRP A 1 321 ? 76.795  129.770 95.197  1.00 70.66 ? 321 TRP A CD1   1 
ATOM   2370 C  CD2   . TRP A 1 321 ? 77.265  129.182 97.299  1.00 70.66 ? 321 TRP A CD2   1 
ATOM   2371 N  NE1   . TRP A 1 321 ? 77.841  130.544 95.622  1.00 70.66 ? 321 TRP A NE1   1 
ATOM   2372 C  CE2   . TRP A 1 321 ? 78.147  130.206 96.912  1.00 70.66 ? 321 TRP A CE2   1 
ATOM   2373 C  CE3   . TRP A 1 321 ? 77.371  128.654 98.585  1.00 70.66 ? 321 TRP A CE3   1 
ATOM   2374 C  CZ2   . TRP A 1 321 ? 79.121  130.714 97.766  1.00 70.66 ? 321 TRP A CZ2   1 
ATOM   2375 C  CZ3   . TRP A 1 321 ? 78.341  129.155 99.429  1.00 70.66 ? 321 TRP A CZ3   1 
ATOM   2376 C  CH2   . TRP A 1 321 ? 79.200  130.178 99.018  1.00 70.66 ? 321 TRP A CH2   1 
ATOM   2377 N  N     . ASN A 1 322 ? 73.414  130.602 97.222  1.00 85.10 ? 322 ASN A N     1 
ATOM   2378 C  CA    . ASN A 1 322 ? 73.054  131.973 96.855  1.00 85.10 ? 322 ASN A CA    1 
ATOM   2379 C  C     . ASN A 1 322 ? 73.867  132.965 97.684  1.00 85.10 ? 322 ASN A C     1 
ATOM   2380 O  O     . ASN A 1 322 ? 73.827  132.951 98.915  1.00 85.10 ? 322 ASN A O     1 
ATOM   2381 C  CB    . ASN A 1 322 ? 71.559  132.244 97.058  1.00 85.10 ? 322 ASN A CB    1 
ATOM   2382 C  CG    . ASN A 1 322 ? 70.714  131.807 95.880  1.00 85.10 ? 322 ASN A CG    1 
ATOM   2383 O  OD1   . ASN A 1 322 ? 71.185  131.777 94.745  1.00 85.10 ? 322 ASN A OD1   1 
ATOM   2384 N  ND2   . ASN A 1 322 ? 69.443  131.514 96.136  1.00 85.10 ? 322 ASN A ND2   1 
ATOM   2385 N  N     . THR B 1 6   ? 74.719  57.543  86.043  1.00 67.59 ? 6   THR B N     1 
ATOM   2386 C  CA    . THR B 1 6   ? 73.920  58.733  85.770  1.00 67.59 ? 6   THR B CA    1 
ATOM   2387 C  C     . THR B 1 6   ? 74.848  59.942  85.680  1.00 67.59 ? 6   THR B C     1 
ATOM   2388 O  O     . THR B 1 6   ? 75.383  60.389  86.688  1.00 67.59 ? 6   THR B O     1 
ATOM   2389 C  CB    . THR B 1 6   ? 72.879  58.955  86.869  1.00 67.59 ? 6   THR B CB    1 
ATOM   2390 O  OG1   . THR B 1 6   ? 72.007  57.820  86.927  1.00 67.59 ? 6   THR B OG1   1 
ATOM   2391 C  CG2   . THR B 1 6   ? 72.051  60.189  86.572  1.00 67.59 ? 6   THR B CG2   1 
ATOM   2392 N  N     . ILE B 1 7   ? 75.021  60.476  84.471  1.00 63.91 ? 7   ILE B N     1 
ATOM   2393 C  CA    . ILE B 1 7   ? 75.905  61.610  84.211  1.00 63.91 ? 7   ILE B CA    1 
ATOM   2394 C  C     . ILE B 1 7   ? 75.091  62.893  84.124  1.00 63.91 ? 7   ILE B C     1 
ATOM   2395 O  O     . ILE B 1 7   ? 74.066  62.939  83.439  1.00 63.91 ? 7   ILE B O     1 
ATOM   2396 C  CB    . ILE B 1 7   ? 76.720  61.390  82.923  1.00 63.91 ? 7   ILE B CB    1 
ATOM   2397 C  CG1   . ILE B 1 7   ? 77.922  60.467  83.162  1.00 63.91 ? 7   ILE B CG1   1 
ATOM   2398 C  CG2   . ILE B 1 7   ? 77.197  62.702  82.358  1.00 63.91 ? 7   ILE B CG2   1 
ATOM   2399 C  CD1   . ILE B 1 7   ? 77.600  59.072  83.663  1.00 63.91 ? 7   ILE B CD1   1 
ATOM   2400 N  N     . LEU B 1 8   ? 75.557  63.942  84.801  1.00 62.72 ? 8   LEU B N     1 
ATOM   2401 C  CA    . LEU B 1 8   ? 74.923  65.253  84.769  1.00 62.72 ? 8   LEU B CA    1 
ATOM   2402 C  C     . LEU B 1 8   ? 75.972  66.305  84.452  1.00 62.72 ? 8   LEU B C     1 
ATOM   2403 O  O     . LEU B 1 8   ? 77.037  66.309  85.071  1.00 62.72 ? 8   LEU B O     1 
ATOM   2404 C  CB    . LEU B 1 8   ? 74.283  65.573  86.118  1.00 62.72 ? 8   LEU B CB    1 
ATOM   2405 C  CG    . LEU B 1 8   ? 73.203  64.634  86.654  1.00 62.72 ? 8   LEU B CG    1 
ATOM   2406 C  CD1   . LEU B 1 8   ? 72.798  65.079  88.038  1.00 62.72 ? 8   LEU B CD1   1 
ATOM   2407 C  CD2   . LEU B 1 8   ? 72.005  64.561  85.729  1.00 62.72 ? 8   LEU B CD2   1 
ATOM   2408 N  N     . ALA B 1 9   ? 75.690  67.196  83.504  1.00 58.98 ? 9   ALA B N     1 
ATOM   2409 C  CA    . ALA B 1 9   ? 76.603  68.287  83.173  1.00 58.98 ? 9   ALA B CA    1 
ATOM   2410 C  C     . ALA B 1 9   ? 76.021  69.573  83.735  1.00 58.98 ? 9   ALA B C     1 
ATOM   2411 O  O     . ALA B 1 9   ? 74.933  69.982  83.337  1.00 58.98 ? 9   ALA B O     1 
ATOM   2412 C  CB    . ALA B 1 9   ? 76.812  68.405  81.665  1.00 58.98 ? 9   ALA B CB    1 
ATOM   2413 N  N     . VAL B 1 10  ? 76.768  70.239  84.608  1.00 54.89 ? 10  VAL B N     1 
ATOM   2414 C  CA    . VAL B 1 10  ? 76.305  71.440  85.296  1.00 54.89 ? 10  VAL B CA    1 
ATOM   2415 C  C     . VAL B 1 10  ? 77.112  72.666  84.899  1.00 54.89 ? 10  VAL B C     1 
ATOM   2416 O  O     . VAL B 1 10  ? 78.345  72.647  84.921  1.00 54.89 ? 10  VAL B O     1 
ATOM   2417 C  CB    . VAL B 1 10  ? 76.311  71.240  86.824  1.00 54.89 ? 10  VAL B CB    1 
ATOM   2418 C  CG1   . VAL B 1 10  ? 77.655  70.803  87.311  1.00 54.89 ? 10  VAL B CG1   1 
ATOM   2419 C  CG2   . VAL B 1 10  ? 75.921  72.530  87.525  1.00 54.89 ? 10  VAL B CG2   1 
ATOM   2420 N  N     . ASP B 1 11  ? 76.408  73.715  84.489  1.00 57.37 ? 11  ASP B N     1 
ATOM   2421 C  CA    . ASP B 1 11  ? 76.989  75.030  84.245  1.00 57.37 ? 11  ASP B CA    1 
ATOM   2422 C  C     . ASP B 1 11  ? 76.792  75.735  85.581  1.00 57.37 ? 11  ASP B C     1 
ATOM   2423 O  O     . ASP B 1 11  ? 75.770  76.367  85.830  1.00 57.37 ? 11  ASP B O     1 
ATOM   2424 C  CB    . ASP B 1 11  ? 76.325  75.750  83.078  1.00 57.37 ? 11  ASP B CB    1 
ATOM   2425 C  CG    . ASP B 1 11  ? 76.814  77.183  82.919  1.00 57.37 ? 11  ASP B CG    1 
ATOM   2426 O  OD1   . ASP B 1 11  ? 77.846  77.537  83.527  1.00 57.37 ? 11  ASP B OD1   1 
ATOM   2427 O  OD2   . ASP B 1 11  ? 76.217  77.952  82.140  1.00 57.37 ? 11  ASP B OD2   1 
ATOM   2428 N  N     . TRP B 1 12  ? 77.777  75.584  86.464  1.00 49.24 ? 12  TRP B N     1 
ATOM   2429 C  CA    . TRP B 1 12  ? 77.683  76.031  87.845  1.00 49.24 ? 12  TRP B CA    1 
ATOM   2430 C  C     . TRP B 1 12  ? 77.609  77.546  87.993  1.00 49.24 ? 12  TRP B C     1 
ATOM   2431 O  O     . TRP B 1 12  ? 78.014  78.317  87.126  1.00 49.24 ? 12  TRP B O     1 
ATOM   2432 C  CB    . TRP B 1 12  ? 78.852  75.473  88.657  1.00 49.24 ? 12  TRP B CB    1 
ATOM   2433 C  CG    . TRP B 1 12  ? 80.139  76.205  88.467  1.00 49.24 ? 12  TRP B CG    1 
ATOM   2434 C  CD1   . TRP B 1 12  ? 81.059  75.979  87.496  1.00 49.24 ? 12  TRP B CD1   1 
ATOM   2435 C  CD2   . TRP B 1 12  ? 80.610  77.343  89.203  1.00 49.24 ? 12  TRP B CD2   1 
ATOM   2436 N  NE1   . TRP B 1 12  ? 82.096  76.863  87.604  1.00 49.24 ? 12  TRP B NE1   1 
ATOM   2437 C  CE2   . TRP B 1 12  ? 81.841  77.720  88.639  1.00 49.24 ? 12  TRP B CE2   1 
ATOM   2438 C  CE3   . TRP B 1 12  ? 80.113  78.074  90.286  1.00 49.24 ? 12  TRP B CE3   1 
ATOM   2439 C  CZ2   . TRP B 1 12  ? 82.587  78.779  89.127  1.00 49.24 ? 12  TRP B CZ2   1 
ATOM   2440 C  CZ3   . TRP B 1 12  ? 80.852  79.129  90.761  1.00 49.24 ? 12  TRP B CZ3   1 
ATOM   2441 C  CH2   . TRP B 1 12  ? 82.080  79.467  90.189  1.00 49.24 ? 12  TRP B CH2   1 
ATOM   2442 N  N     . SER B 1 13  ? 77.056  77.953  89.135  1.00 52.92 ? 13  SER B N     1 
ATOM   2443 C  CA    . SER B 1 13  ? 76.869  79.347  89.498  1.00 52.92 ? 13  SER B CA    1 
ATOM   2444 C  C     . SER B 1 13  ? 76.588  79.427  90.988  1.00 52.92 ? 13  SER B C     1 
ATOM   2445 O  O     . SER B 1 13  ? 76.310  78.416  91.635  1.00 52.92 ? 13  SER B O     1 
ATOM   2446 C  CB    . SER B 1 13  ? 75.715  79.967  88.716  1.00 52.92 ? 13  SER B CB    1 
ATOM   2447 O  OG    . SER B 1 13  ? 76.096  80.242  87.387  1.00 52.92 ? 13  SER B OG    1 
ATOM   2448 N  N     . HIS B 1 14  ? 76.705  80.637  91.539  1.00 54.89 ? 14  HIS B N     1 
ATOM   2449 C  CA    . HIS B 1 14  ? 76.322  80.834  92.931  1.00 54.89 ? 14  HIS B CA    1 
ATOM   2450 C  C     . HIS B 1 14  ? 74.834  81.124  93.078  1.00 54.89 ? 14  HIS B C     1 
ATOM   2451 O  O     . HIS B 1 14  ? 74.173  80.546  93.944  1.00 54.89 ? 14  HIS B O     1 
ATOM   2452 C  CB    . HIS B 1 14  ? 77.122  81.986  93.563  1.00 54.89 ? 14  HIS B CB    1 
ATOM   2453 C  CG    . HIS B 1 14  ? 78.596  81.737  93.663  1.00 54.89 ? 14  HIS B CG    1 
ATOM   2454 N  ND1   . HIS B 1 14  ? 79.134  80.799  94.516  1.00 54.89 ? 14  HIS B ND1   1 
ATOM   2455 C  CD2   . HIS B 1 14  ? 79.641  82.295  93.012  1.00 54.89 ? 14  HIS B CD2   1 
ATOM   2456 C  CE1   . HIS B 1 14  ? 80.447  80.791  94.387  1.00 54.89 ? 14  HIS B CE1   1 
ATOM   2457 N  NE2   . HIS B 1 14  ? 80.779  81.691  93.481  1.00 54.89 ? 14  HIS B NE2   1 
ATOM   2458 N  N     . GLU B 1 15  ? 74.286  81.984  92.222  1.00 65.28 ? 15  GLU B N     1 
ATOM   2459 C  CA    . GLU B 1 15  ? 72.869  82.316  92.257  1.00 65.28 ? 15  GLU B CA    1 
ATOM   2460 C  C     . GLU B 1 15  ? 72.070  81.229  91.549  1.00 65.28 ? 15  GLU B C     1 
ATOM   2461 O  O     . GLU B 1 15  ? 72.331  80.933  90.380  1.00 65.28 ? 15  GLU B O     1 
ATOM   2462 C  CB    . GLU B 1 15  ? 72.632  83.680  91.624  1.00 65.28 ? 15  GLU B CB    1 
ATOM   2463 C  CG    . GLU B 1 15  ? 71.205  84.171  91.798  1.00 65.28 ? 15  GLU B CG    1 
ATOM   2464 C  CD    . GLU B 1 15  ? 71.026  85.614  91.389  1.00 65.28 ? 15  GLU B CD    1 
ATOM   2465 O  OE1   . GLU B 1 15  ? 71.965  86.418  91.591  1.00 65.28 ? 15  GLU B OE1   1 
ATOM   2466 O  OE2   . GLU B 1 15  ? 69.941  85.946  90.878  1.00 65.28 ? 15  GLU B OE2   1 
ATOM   2467 N  N     . GLU B 1 16  ? 71.094  80.637  92.250  1.00 68.35 ? 16  GLU B N     1 
ATOM   2468 C  CA    . GLU B 1 16  ? 70.317  79.528  91.693  1.00 68.35 ? 16  GLU B CA    1 
ATOM   2469 C  C     . GLU B 1 16  ? 69.508  79.909  90.461  1.00 68.35 ? 16  GLU B C     1 
ATOM   2470 O  O     . GLU B 1 16  ? 69.108  79.021  89.704  1.00 68.35 ? 16  GLU B O     1 
ATOM   2471 C  CB    . GLU B 1 16  ? 69.391  78.920  92.751  1.00 68.35 ? 16  GLU B CB    1 
ATOM   2472 C  CG    . GLU B 1 16  ? 68.249  79.807  93.215  1.00 68.35 ? 16  GLU B CG    1 
ATOM   2473 C  CD    . GLU B 1 16  ? 67.372  79.132  94.274  1.00 68.35 ? 16  GLU B CD    1 
ATOM   2474 O  OE1   . GLU B 1 16  ? 67.710  79.195  95.474  1.00 68.35 ? 16  GLU B OE1   1 
ATOM   2475 O  OE2   . GLU B 1 16  ? 66.315  78.577  93.907  1.00 68.35 ? 16  GLU B OE2   1 
ATOM   2476 N  N     . ARG B 1 17  ? 69.248  81.195  90.239  1.00 68.77 ? 17  ARG B N     1 
ATOM   2477 C  CA    . ARG B 1 17  ? 68.564  81.589  89.015  1.00 68.77 ? 17  ARG B CA    1 
ATOM   2478 C  C     . ARG B 1 17  ? 69.406  81.281  87.782  1.00 68.77 ? 17  ARG B C     1 
ATOM   2479 O  O     . ARG B 1 17  ? 68.858  80.999  86.715  1.00 68.77 ? 17  ARG B O     1 
ATOM   2480 C  CB    . ARG B 1 17  ? 68.173  83.069  89.071  1.00 68.77 ? 17  ARG B CB    1 
ATOM   2481 C  CG    . ARG B 1 17  ? 67.139  83.390  90.157  1.00 68.77 ? 17  ARG B CG    1 
ATOM   2482 C  CD    . ARG B 1 17  ? 66.458  84.766  89.962  1.00 68.77 ? 17  ARG B CD    1 
ATOM   2483 N  NE    . ARG B 1 17  ? 67.353  85.889  90.224  1.00 68.77 ? 17  ARG B NE    1 
ATOM   2484 C  CZ    . ARG B 1 17  ? 66.963  87.137  90.456  1.00 68.77 ? 17  ARG B CZ    1 
ATOM   2485 N  NH1   . ARG B 1 17  ? 65.688  87.488  90.400  1.00 68.77 ? 17  ARG B NH1   1 
ATOM   2486 N  NH2   . ARG B 1 17  ? 67.880  88.062  90.735  1.00 68.77 ? 17  ARG B NH2   1 
ATOM   2487 N  N     . LYS B 1 18  ? 70.732  81.346  87.904  1.00 63.51 ? 18  LYS B N     1 
ATOM   2488 C  CA    . LYS B 1 18  ? 71.649  81.034  86.810  1.00 63.51 ? 18  LYS B CA    1 
ATOM   2489 C  C     . LYS B 1 18  ? 71.962  79.543  86.661  1.00 63.51 ? 18  LYS B C     1 
ATOM   2490 O  O     . LYS B 1 18  ? 72.351  79.111  85.573  1.00 63.51 ? 18  LYS B O     1 
ATOM   2491 C  CB    . LYS B 1 18  ? 72.955  81.796  87.004  1.00 63.51 ? 18  LYS B CB    1 
ATOM   2492 C  CG    . LYS B 1 18  ? 72.921  83.254  86.638  1.00 63.51 ? 18  LYS B CG    1 
ATOM   2493 C  CD    . LYS B 1 18  ? 74.337  83.789  86.655  1.00 63.51 ? 18  LYS B CD    1 
ATOM   2494 C  CE    . LYS B 1 18  ? 74.432  85.208  86.170  1.00 63.51 ? 18  LYS B CE    1 
ATOM   2495 N  NZ    . LYS B 1 18  ? 75.849  85.628  86.104  1.00 63.51 ? 18  LYS B NZ    1 
ATOM   2496 N  N     . LEU B 1 19  ? 71.866  78.762  87.731  1.00 64.60 ? 19  LEU B N     1 
ATOM   2497 C  CA    . LEU B 1 19  ? 72.237  77.352  87.681  1.00 64.60 ? 19  LEU B CA    1 
ATOM   2498 C  C     . LEU B 1 19  ? 71.492  76.593  86.589  1.00 64.60 ? 19  LEU B C     1 
ATOM   2499 O  O     . LEU B 1 19  ? 70.290  76.772  86.389  1.00 64.60 ? 19  LEU B O     1 
ATOM   2500 C  CB    . LEU B 1 19  ? 71.980  76.710  89.041  1.00 64.60 ? 19  LEU B CB    1 
ATOM   2501 C  CG    . LEU B 1 19  ? 72.319  75.231  89.245  1.00 64.60 ? 19  LEU B CG    1 
ATOM   2502 C  CD1   . LEU B 1 19  ? 73.790  74.963  89.090  1.00 64.60 ? 19  LEU B CD1   1 
ATOM   2503 C  CD2   . LEU B 1 19  ? 71.865  74.810  90.617  1.00 64.60 ? 19  LEU B CD2   1 
ATOM   2504 N  N     . ALA B 1 20  ? 72.211  75.704  85.908  1.00 62.66 ? 20  ALA B N     1 
ATOM   2505 C  CA    . ALA B 1 20  ? 71.646  74.888  84.845  1.00 62.66 ? 20  ALA B CA    1 
ATOM   2506 C  C     . ALA B 1 20  ? 72.345  73.541  84.804  1.00 62.66 ? 20  ALA B C     1 
ATOM   2507 O  O     . ALA B 1 20  ? 73.562  73.461  84.963  1.00 62.66 ? 20  ALA B O     1 
ATOM   2508 C  CB    . ALA B 1 20  ? 71.797  75.579  83.491  1.00 62.66 ? 20  ALA B CB    1 
ATOM   2509 N  N     . ILE B 1 21  ? 71.564  72.485  84.602  1.00 64.85 ? 21  ILE B N     1 
ATOM   2510 C  CA    . ILE B 1 21  ? 72.062  71.116  84.525  1.00 64.85 ? 21  ILE B CA    1 
ATOM   2511 C  C     . ILE B 1 21  ? 71.425  70.433  83.324  1.00 64.85 ? 21  ILE B C     1 
ATOM   2512 O  O     . ILE B 1 21  ? 70.240  70.630  83.051  1.00 64.85 ? 21  ILE B O     1 
ATOM   2513 C  CB    . ILE B 1 21  ? 71.772  70.316  85.815  1.00 64.85 ? 21  ILE B CB    1 
ATOM   2514 C  CG1   . ILE B 1 21  ? 72.355  71.008  87.041  1.00 64.85 ? 21  ILE B CG1   1 
ATOM   2515 C  CG2   . ILE B 1 21  ? 72.352  68.928  85.731  1.00 64.85 ? 21  ILE B CG2   1 
ATOM   2516 C  CD1   . ILE B 1 21  ? 71.410  71.916  87.754  1.00 64.85 ? 21  ILE B CD1   1 
ATOM   2517 N  N     . PHE B 1 22  ? 72.216  69.661  82.588  1.00 65.34 ? 22  PHE B N     1 
ATOM   2518 C  CA    . PHE B 1 22  ? 71.733  68.880  81.458  1.00 65.34 ? 22  PHE B CA    1 
ATOM   2519 C  C     . PHE B 1 22  ? 71.959  67.413  81.791  1.00 65.34 ? 22  PHE B C     1 
ATOM   2520 O  O     . PHE B 1 22  ? 73.091  67.007  82.082  1.00 65.34 ? 22  PHE B O     1 
ATOM   2521 C  CB    . PHE B 1 22  ? 72.462  69.277  80.173  1.00 65.34 ? 22  PHE B CB    1 
ATOM   2522 C  CG    . PHE B 1 22  ? 71.957  68.590  78.941  1.00 65.34 ? 22  PHE B CG    1 
ATOM   2523 C  CD1   . PHE B 1 22  ? 70.656  68.759  78.521  1.00 65.34 ? 22  PHE B CD1   1 
ATOM   2524 C  CD2   . PHE B 1 22  ? 72.789  67.781  78.193  1.00 65.34 ? 22  PHE B CD2   1 
ATOM   2525 C  CE1   . PHE B 1 22  ? 70.200  68.128  77.387  1.00 65.34 ? 22  PHE B CE1   1 
ATOM   2526 C  CE2   . PHE B 1 22  ? 72.332  67.148  77.050  1.00 65.34 ? 22  PHE B CE2   1 
ATOM   2527 C  CZ    . PHE B 1 22  ? 71.044  67.315  76.653  1.00 65.34 ? 22  PHE B CZ    1 
ATOM   2528 N  N     . ASP B 1 23  ? 70.883  66.625  81.758  1.00 71.29 ? 23  ASP B N     1 
ATOM   2529 C  CA    . ASP B 1 23  ? 70.941  65.203  82.073  1.00 71.29 ? 23  ASP B CA    1 
ATOM   2530 C  C     . ASP B 1 23  ? 71.160  64.332  80.843  1.00 71.29 ? 23  ASP B C     1 
ATOM   2531 O  O     . ASP B 1 23  ? 71.116  63.104  80.951  1.00 71.29 ? 23  ASP B O     1 
ATOM   2532 C  CB    . ASP B 1 23  ? 69.689  64.761  82.856  1.00 71.29 ? 23  ASP B CB    1 
ATOM   2533 C  CG    . ASP B 1 23  ? 68.426  64.651  81.997  1.00 71.29 ? 23  ASP B CG    1 
ATOM   2534 O  OD1   . ASP B 1 23  ? 68.458  64.953  80.791  1.00 71.29 ? 23  ASP B OD1   1 
ATOM   2535 O  OD2   . ASP B 1 23  ? 67.385  64.221  82.544  1.00 71.29 ? 23  ASP B OD2   1 
ATOM   2536 N  N     . GLY B 1 24  ? 71.387  64.942  79.686  1.00 70.60 ? 24  GLY B N     1 
ATOM   2537 C  CA    . GLY B 1 24  ? 71.535  64.243  78.432  1.00 70.60 ? 24  GLY B CA    1 
ATOM   2538 C  C     . GLY B 1 24  ? 70.271  64.205  77.603  1.00 70.60 ? 24  GLY B C     1 
ATOM   2539 O  O     . GLY B 1 24  ? 70.326  63.814  76.431  1.00 70.60 ? 24  GLY B O     1 
ATOM   2540 N  N     . LYS B 1 25  ? 69.143  64.628  78.171  1.00 72.08 ? 25  LYS B N     1 
ATOM   2541 C  CA    . LYS B 1 25  ? 67.866  64.638  77.474  1.00 72.08 ? 25  LYS B CA    1 
ATOM   2542 C  C     . LYS B 1 25  ? 67.086  65.933  77.708  1.00 72.08 ? 25  LYS B C     1 
ATOM   2543 O  O     . LYS B 1 25  ? 66.436  66.440  76.790  1.00 72.08 ? 25  LYS B O     1 
ATOM   2544 C  CB    . LYS B 1 25  ? 67.038  63.431  77.923  1.00 72.08 ? 25  LYS B CB    1 
ATOM   2545 C  CG    . LYS B 1 25  ? 67.673  62.087  77.605  1.00 72.08 ? 25  LYS B CG    1 
ATOM   2546 C  CD    . LYS B 1 25  ? 66.831  60.942  78.129  1.00 72.08 ? 25  LYS B CD    1 
ATOM   2547 C  CE    . LYS B 1 25  ? 67.449  59.595  77.803  1.00 72.08 ? 25  LYS B CE    1 
ATOM   2548 N  NZ    . LYS B 1 25  ? 66.641  58.490  78.384  1.00 72.08 ? 25  LYS B NZ    1 
ATOM   2549 N  N     . LYS B 1 26  ? 67.169  66.493  78.916  1.00 71.03 ? 26  LYS B N     1 
ATOM   2550 C  CA    . LYS B 1 26  ? 66.455  67.714  79.282  1.00 71.03 ? 26  LYS B CA    1 
ATOM   2551 C  C     . LYS B 1 26  ? 67.306  68.601  80.188  1.00 71.03 ? 26  LYS B C     1 
ATOM   2552 O  O     . LYS B 1 26  ? 68.298  68.164  80.773  1.00 71.03 ? 26  LYS B O     1 
ATOM   2553 C  CB    . LYS B 1 26  ? 65.125  67.386  79.968  1.00 71.03 ? 26  LYS B CB    1 
ATOM   2554 C  CG    . LYS B 1 26  ? 65.297  66.684  81.300  1.00 71.03 ? 26  LYS B CG    1 
ATOM   2555 C  CD    . LYS B 1 26  ? 63.974  66.392  81.971  1.00 71.03 ? 26  LYS B CD    1 
ATOM   2556 C  CE    . LYS B 1 26  ? 64.188  65.607  83.255  1.00 71.03 ? 26  LYS B CE    1 
ATOM   2557 N  NZ    . LYS B 1 26  ? 62.902  65.234  83.905  1.00 71.03 ? 26  LYS B NZ    1 
ATOM   2558 N  N     . ILE B 1 27  ? 66.881  69.859  80.311  1.00 68.75 ? 27  ILE B N     1 
ATOM   2559 C  CA    . ILE B 1 27  ? 67.548  70.862  81.136  1.00 68.75 ? 27  ILE B CA    1 
ATOM   2560 C  C     . ILE B 1 27  ? 66.837  70.953  82.480  1.00 68.75 ? 27  ILE B C     1 
ATOM   2561 O  O     . ILE B 1 27  ? 65.607  71.054  82.535  1.00 68.75 ? 27  ILE B O     1 
ATOM   2562 C  CB    . ILE B 1 27  ? 67.541  72.236  80.439  1.00 68.75 ? 27  ILE B CB    1 
ATOM   2563 C  CG1   . ILE B 1 27  ? 68.318  72.218  79.120  1.00 68.75 ? 27  ILE B CG1   1 
ATOM   2564 C  CG2   . ILE B 1 27  ? 68.107  73.302  81.355  1.00 68.75 ? 27  ILE B CG2   1 
ATOM   2565 C  CD1   . ILE B 1 27  ? 69.812  72.211  79.269  1.00 68.75 ? 27  ILE B CD1   1 
ATOM   2566 N  N     . ARG B 1 28  ? 67.609  70.922  83.563  1.00 68.99 ? 28  ARG B N     1 
ATOM   2567 C  CA    . ARG B 1 28  ? 67.104  71.035  84.922  1.00 68.99 ? 28  ARG B CA    1 
ATOM   2568 C  C     . ARG B 1 28  ? 67.681  72.271  85.590  1.00 68.99 ? 28  ARG B C     1 
ATOM   2569 O  O     . ARG B 1 28  ? 68.777  72.723  85.254  1.00 68.99 ? 28  ARG B O     1 
ATOM   2570 C  CB    . ARG B 1 28  ? 67.448  69.810  85.761  1.00 68.99 ? 28  ARG B CB    1 
ATOM   2571 C  CG    . ARG B 1 28  ? 66.901  68.528  85.207  1.00 68.99 ? 28  ARG B CG    1 
ATOM   2572 C  CD    . ARG B 1 28  ? 66.758  67.491  86.294  1.00 68.99 ? 28  ARG B CD    1 
ATOM   2573 N  NE    . ARG B 1 28  ? 68.045  66.983  86.747  1.00 68.99 ? 28  ARG B NE    1 
ATOM   2574 C  CZ    . ARG B 1 28  ? 68.197  66.054  87.683  1.00 68.99 ? 28  ARG B CZ    1 
ATOM   2575 N  NH1   . ARG B 1 28  ? 67.157  65.503  88.291  1.00 68.99 ? 28  ARG B NH1   1 
ATOM   2576 N  NH2   . ARG B 1 28  ? 69.424  65.676  88.026  1.00 68.99 ? 28  ARG B NH2   1 
ATOM   2577 N  N     . LYS B 1 29  ? 66.909  72.848  86.500  1.00 69.61 ? 29  LYS B N     1 
ATOM   2578 C  CA    . LYS B 1 29  ? 67.331  74.045  87.208  1.00 69.61 ? 29  LYS B CA    1 
ATOM   2579 C  C     . LYS B 1 29  ? 68.075  73.775  88.513  1.00 69.61 ? 29  LYS B C     1 
ATOM   2580 O  O     . LYS B 1 29  ? 68.730  74.689  89.025  1.00 69.61 ? 29  LYS B O     1 
ATOM   2581 C  CB    . LYS B 1 29  ? 66.116  74.932  87.493  1.00 69.61 ? 29  LYS B CB    1 
ATOM   2582 C  CG    . LYS B 1 29  ? 66.428  76.413  87.541  1.00 69.61 ? 29  LYS B CG    1 
ATOM   2583 C  CD    . LYS B 1 29  ? 66.798  76.950  86.173  1.00 69.61 ? 29  LYS B CD    1 
ATOM   2584 C  CE    . LYS B 1 29  ? 67.254  78.395  86.257  1.00 69.61 ? 29  LYS B CE    1 
ATOM   2585 N  NZ    . LYS B 1 29  ? 68.260  78.711  85.202  1.00 69.61 ? 29  LYS B NZ    1 
ATOM   2586 N  N     . LYS B 1 30  ? 67.985  72.570  89.080  1.00 70.76 ? 30  LYS B N     1 
ATOM   2587 C  CA    . LYS B 1 30  ? 68.621  72.281  90.362  1.00 70.76 ? 30  LYS B CA    1 
ATOM   2588 C  C     . LYS B 1 30  ? 69.170  70.859  90.394  1.00 70.76 ? 30  LYS B C     1 
ATOM   2589 O  O     . LYS B 1 30  ? 68.707  69.982  89.664  1.00 70.76 ? 30  LYS B O     1 
ATOM   2590 C  CB    . LYS B 1 30  ? 67.616  72.479  91.500  1.00 70.76 ? 30  LYS B CB    1 
ATOM   2591 C  CG    . LYS B 1 30  ? 67.182  73.925  91.676  1.00 70.76 ? 30  LYS B CG    1 
ATOM   2592 C  CD    . LYS B 1 30  ? 66.294  74.122  92.885  1.00 70.76 ? 30  LYS B CD    1 
ATOM   2593 C  CE    . LYS B 1 30  ? 65.951  75.590  93.062  1.00 70.76 ? 30  LYS B CE    1 
ATOM   2594 N  NZ    . LYS B 1 30  ? 65.098  75.834  94.256  1.00 70.76 ? 30  LYS B NZ    1 
ATOM   2595 N  N     . LEU B 1 31  ? 70.198  70.647  91.232  1.00 70.46 ? 31  LEU B N     1 
ATOM   2596 C  CA    . LEU B 1 31  ? 70.836  69.350  91.414  1.00 70.46 ? 31  LEU B CA    1 
ATOM   2597 C  C     . LEU B 1 31  ? 70.047  68.421  92.340  1.00 70.46 ? 31  LEU B C     1 
ATOM   2598 O  O     . LEU B 1 31  ? 69.322  68.876  93.226  1.00 70.46 ? 31  LEU B O     1 
ATOM   2599 C  CB    . LEU B 1 31  ? 72.243  69.523  91.970  1.00 70.46 ? 31  LEU B CB    1 
ATOM   2600 C  CG    . LEU B 1 31  ? 73.329  70.031  91.031  1.00 70.46 ? 31  LEU B CG    1 
ATOM   2601 C  CD1   . LEU B 1 31  ? 74.527  70.503  91.837  1.00 70.46 ? 31  LEU B CD1   1 
ATOM   2602 C  CD2   . LEU B 1 31  ? 73.720  68.980  90.017  1.00 70.46 ? 31  LEU B CD2   1 
ATOM   2603 N  N     . PRO B 1 32  ? 70.193  67.115  92.158  1.00 73.27 ? 32  PRO B N     1 
ATOM   2604 C  CA    . PRO B 1 32  ? 69.521  66.128  93.008  1.00 73.27 ? 32  PRO B CA    1 
ATOM   2605 C  C     . PRO B 1 32  ? 70.228  65.952  94.349  1.00 73.27 ? 32  PRO B C     1 
ATOM   2606 O  O     . PRO B 1 32  ? 71.223  66.601  94.653  1.00 73.27 ? 32  PRO B O     1 
ATOM   2607 C  CB    . PRO B 1 32  ? 69.603  64.855  92.170  1.00 73.27 ? 32  PRO B CB    1 
ATOM   2608 C  CG    . PRO B 1 32  ? 70.893  64.988  91.473  1.00 73.27 ? 32  PRO B CG    1 
ATOM   2609 C  CD    . PRO B 1 32  ? 71.018  66.456  91.134  1.00 73.27 ? 32  PRO B CD    1 
ATOM   2610 N  N     . GLU B 1 33  ? 69.673  65.062  95.163  1.00 76.63 ? 33  GLU B N     1 
ATOM   2611 C  CA    . GLU B 1 33  ? 70.310  64.724  96.428  1.00 76.63 ? 33  GLU B CA    1 
ATOM   2612 C  C     . GLU B 1 33  ? 71.562  63.890  96.155  1.00 76.63 ? 33  GLU B C     1 
ATOM   2613 O  O     . GLU B 1 33  ? 71.585  63.096  95.211  1.00 76.63 ? 33  GLU B O     1 
ATOM   2614 C  CB    . GLU B 1 33  ? 69.347  63.961  97.341  1.00 76.63 ? 33  GLU B CB    1 
ATOM   2615 C  CG    . GLU B 1 33  ? 68.129  64.761  97.807  1.00 76.63 ? 33  GLU B CG    1 
ATOM   2616 C  CD    . GLU B 1 33  ? 68.480  66.001  98.631  1.00 76.63 ? 33  GLU B CD    1 
ATOM   2617 O  OE1   . GLU B 1 33  ? 69.467  65.976  99.396  1.00 76.63 ? 33  GLU B OE1   1 
ATOM   2618 O  OE2   . GLU B 1 33  ? 67.756  67.010  98.514  1.00 76.63 ? 33  GLU B OE2   1 
ATOM   2619 N  N     . PRO B 1 34  ? 72.630  64.084  96.926  1.00 70.38 ? 34  PRO B N     1 
ATOM   2620 C  CA    . PRO B 1 34  ? 73.870  63.336  96.687  1.00 70.38 ? 34  PRO B CA    1 
ATOM   2621 C  C     . PRO B 1 34  ? 73.706  61.821  96.759  1.00 70.38 ? 34  PRO B C     1 
ATOM   2622 O  O     . PRO B 1 34  ? 73.057  61.280  97.657  1.00 70.38 ? 34  PRO B O     1 
ATOM   2623 C  CB    . PRO B 1 34  ? 74.800  63.848  97.791  1.00 70.38 ? 34  PRO B CB    1 
ATOM   2624 C  CG    . PRO B 1 34  ? 74.293  65.214  98.093  1.00 70.38 ? 34  PRO B CG    1 
ATOM   2625 C  CD    . PRO B 1 34  ? 72.807  65.118  97.955  1.00 70.38 ? 34  PRO B CD    1 
ATOM   2626 N  N     . SER B 1 35  ? 74.324  61.143  95.797  1.00 71.50 ? 35  SER B N     1 
ATOM   2627 C  CA    . SER B 1 35  ? 74.326  59.692  95.700  1.00 71.50 ? 35  SER B CA    1 
ATOM   2628 C  C     . SER B 1 35  ? 75.500  59.277  94.826  1.00 71.50 ? 35  SER B C     1 
ATOM   2629 O  O     . SER B 1 35  ? 75.756  59.906  93.800  1.00 71.50 ? 35  SER B O     1 
ATOM   2630 C  CB    . SER B 1 35  ? 73.014  59.167  95.112  1.00 71.50 ? 35  SER B CB    1 
ATOM   2631 O  OG    . SER B 1 35  ? 73.067  57.761  94.911  1.00 71.50 ? 35  SER B OG    1 
ATOM   2632 N  N     . SER B 1 36  ? 76.181  58.195  95.207  1.00 70.43 ? 36  SER B N     1 
ATOM   2633 C  CA    . SER B 1 36  ? 77.330  57.745  94.429  1.00 70.43 ? 36  SER B CA    1 
ATOM   2634 C  C     . SER B 1 36  ? 76.951  57.271  93.032  1.00 70.43 ? 36  SER B C     1 
ATOM   2635 O  O     . SER B 1 36  ? 77.842  57.023  92.215  1.00 70.43 ? 36  SER B O     1 
ATOM   2636 C  CB    . SER B 1 36  ? 78.060  56.634  95.179  1.00 70.43 ? 36  SER B CB    1 
ATOM   2637 O  OG    . SER B 1 36  ? 77.207  55.531  95.400  1.00 70.43 ? 36  SER B OG    1 
ATOM   2638 N  N     . ASP B 1 37  ? 75.656  57.158  92.740  1.00 74.27 ? 37  ASP B N     1 
ATOM   2639 C  CA    . ASP B 1 37  ? 75.174  56.818  91.409  1.00 74.27 ? 37  ASP B CA    1 
ATOM   2640 C  C     . ASP B 1 37  ? 75.335  57.973  90.428  1.00 74.27 ? 37  ASP B C     1 
ATOM   2641 O  O     . ASP B 1 37  ? 75.320  57.751  89.211  1.00 74.27 ? 37  ASP B O     1 
ATOM   2642 C  CB    . ASP B 1 37  ? 73.706  56.389  91.509  1.00 74.27 ? 37  ASP B CB    1 
ATOM   2643 C  CG    . ASP B 1 37  ? 73.124  55.954  90.182  1.00 74.27 ? 37  ASP B CG    1 
ATOM   2644 O  OD1   . ASP B 1 37  ? 73.593  54.943  89.622  1.00 74.27 ? 37  ASP B OD1   1 
ATOM   2645 O  OD2   . ASP B 1 37  ? 72.179  56.616  89.704  1.00 74.27 ? 37  ASP B OD2   1 
ATOM   2646 N  N     . VAL B 1 38  ? 75.499  59.193  90.930  1.00 68.78 ? 38  VAL B N     1 
ATOM   2647 C  CA    . VAL B 1 38  ? 75.577  60.395  90.113  1.00 68.78 ? 38  VAL B CA    1 
ATOM   2648 C  C     . VAL B 1 38  ? 77.023  60.785  89.860  1.00 68.78 ? 38  VAL B C     1 
ATOM   2649 O  O     . VAL B 1 38  ? 77.835  60.829  90.789  1.00 68.78 ? 38  VAL B O     1 
ATOM   2650 C  CB    . VAL B 1 38  ? 74.821  61.552  90.781  1.00 68.78 ? 38  VAL B CB    1 
ATOM   2651 C  CG1   . VAL B 1 38  ? 74.822  62.762  89.882  1.00 68.78 ? 38  VAL B CG1   1 
ATOM   2652 C  CG2   . VAL B 1 38  ? 73.407  61.124  91.114  1.00 68.78 ? 38  VAL B CG2   1 
ATOM   2653 N  N     . ILE B 1 39  ? 77.350  61.026  88.593  1.00 61.64 ? 39  ILE B N     1 
ATOM   2654 C  CA    . ILE B 1 39  ? 78.650  61.530  88.170  1.00 61.64 ? 39  ILE B CA    1 
ATOM   2655 C  C     . ILE B 1 39  ? 78.410  62.924  87.614  1.00 61.64 ? 39  ILE B C     1 
ATOM   2656 O  O     . ILE B 1 39  ? 77.667  63.096  86.643  1.00 61.64 ? 39  ILE B O     1 
ATOM   2657 C  CB    . ILE B 1 39  ? 79.313  60.615  87.131  1.00 61.64 ? 39  ILE B CB    1 
ATOM   2658 C  CG1   . ILE B 1 39  ? 79.642  59.263  87.751  1.00 61.64 ? 39  ILE B CG1   1 
ATOM   2659 C  CG2   . ILE B 1 39  ? 80.570  61.226  86.598  1.00 61.64 ? 39  ILE B CG2   1 
ATOM   2660 C  CD1   . ILE B 1 39  ? 79.988  58.198  86.734  1.00 61.64 ? 39  ILE B CD1   1 
ATOM   2661 N  N     . ILE B 1 40  ? 79.047  63.911  88.208  1.00 55.72 ? 40  ILE B N     1 
ATOM   2662 C  CA    . ILE B 1 40  ? 78.909  65.296  87.796  1.00 55.72 ? 40  ILE B CA    1 
ATOM   2663 C  C     . ILE B 1 40  ? 80.106  65.686  86.951  1.00 55.72 ? 40  ILE B C     1 
ATOM   2664 O  O     . ILE B 1 40  ? 81.232  65.263  87.230  1.00 55.72 ? 40  ILE B O     1 
ATOM   2665 C  CB    . ILE B 1 40  ? 78.798  66.214  89.025  1.00 55.72 ? 40  ILE B CB    1 
ATOM   2666 C  CG1   . ILE B 1 40  ? 77.571  65.851  89.852  1.00 55.72 ? 40  ILE B CG1   1 
ATOM   2667 C  CG2   . ILE B 1 40  ? 78.752  67.669  88.605  1.00 55.72 ? 40  ILE B CG2   1 
ATOM   2668 C  CD1   . ILE B 1 40  ? 77.366  66.748  91.019  1.00 55.72 ? 40  ILE B CD1   1 
ATOM   2669 N  N     . VAL B 1 41  ? 79.861  66.439  85.883  1.00 53.00 ? 41  VAL B N     1 
ATOM   2670 C  CA    . VAL B 1 41  ? 80.915  66.994  85.047  1.00 53.00 ? 41  VAL B CA    1 
ATOM   2671 C  C     . VAL B 1 41  ? 80.688  68.497  85.003  1.00 53.00 ? 41  VAL B C     1 
ATOM   2672 O  O     . VAL B 1 41  ? 79.563  68.958  84.788  1.00 53.00 ? 41  VAL B O     1 
ATOM   2673 C  CB    . VAL B 1 41  ? 80.979  66.357  83.643  1.00 53.00 ? 41  VAL B CB    1 
ATOM   2674 C  CG1   . VAL B 1 41  ? 81.053  64.858  83.746  1.00 53.00 ? 41  VAL B CG1   1 
ATOM   2675 C  CG2   . VAL B 1 41  ? 79.800  66.739  82.797  1.00 53.00 ? 41  VAL B CG2   1 
ATOM   2676 N  N     . ALA B 1 42  ? 81.744  69.260  85.251  1.00 50.87 ? 42  ALA B N     1 
ATOM   2677 C  CA    . ALA B 1 42  ? 81.589  70.695  85.356  1.00 50.87 ? 42  ALA B CA    1 
ATOM   2678 C  C     . ALA B 1 42  ? 82.863  71.393  84.929  1.00 50.87 ? 42  ALA B C     1 
ATOM   2679 O  O     . ALA B 1 42  ? 83.942  70.805  84.895  1.00 50.87 ? 42  ALA B O     1 
ATOM   2680 C  CB    . ALA B 1 42  ? 81.225  71.101  86.784  1.00 50.87 ? 42  ALA B CB    1 
ATOM   2681 N  N     . GLU B 1 43  ? 82.708  72.652  84.558  1.00 51.78 ? 43  GLU B N     1 
ATOM   2682 C  CA    . GLU B 1 43  ? 83.831  73.495  84.187  1.00 51.78 ? 43  GLU B CA    1 
ATOM   2683 C  C     . GLU B 1 43  ? 84.249  74.379  85.361  1.00 51.78 ? 43  GLU B C     1 
ATOM   2684 O  O     . GLU B 1 43  ? 83.822  75.524  85.474  1.00 51.78 ? 43  GLU B O     1 
ATOM   2685 C  CB    . GLU B 1 43  ? 83.467  74.304  82.945  1.00 51.78 ? 43  GLU B CB    1 
ATOM   2686 C  CG    . GLU B 1 43  ? 84.637  74.912  82.229  1.00 51.78 ? 43  GLU B CG    1 
ATOM   2687 C  CD    . GLU B 1 43  ? 84.274  75.453  80.851  1.00 51.78 ? 43  GLU B CD    1 
ATOM   2688 O  OE1   . GLU B 1 43  ? 83.341  76.278  80.758  1.00 51.78 ? 43  GLU B OE1   1 
ATOM   2689 O  OE2   . GLU B 1 43  ? 84.948  75.078  79.869  1.00 51.78 ? 43  GLU B OE2   1 
ATOM   2690 N  N     . ASN B 1 44  ? 85.074  73.820  86.264  1.00 48.02 ? 44  ASN B N     1 
ATOM   2691 C  CA    . ASN B 1 44  ? 85.608  74.540  87.442  1.00 48.02 ? 44  ASN B CA    1 
ATOM   2692 C  C     . ASN B 1 44  ? 84.620  74.813  88.593  1.00 48.02 ? 44  ASN B C     1 
ATOM   2693 O  O     . ASN B 1 44  ? 84.655  75.876  89.206  1.00 48.02 ? 44  ASN B O     1 
ATOM   2694 C  CB    . ASN B 1 44  ? 86.231  75.849  86.952  1.00 48.02 ? 44  ASN B CB    1 
ATOM   2695 C  CG    . ASN B 1 44  ? 87.012  76.543  87.983  1.00 48.02 ? 44  ASN B CG    1 
ATOM   2696 O  OD1   . ASN B 1 44  ? 87.755  75.920  88.730  1.00 48.02 ? 44  ASN B OD1   1 
ATOM   2697 N  ND2   . ASN B 1 44  ? 86.865  77.859  88.040  1.00 48.02 ? 44  ASN B ND2   1 
ATOM   2698 N  N     . ILE B 1 45  ? 83.766  73.851  88.926  1.00 46.30 ? 45  ILE B N     1 
ATOM   2699 C  CA    . ILE B 1 45  ? 82.799  74.035  90.028  1.00 46.30 ? 45  ILE B CA    1 
ATOM   2700 C  C     . ILE B 1 45  ? 83.510  74.165  91.383  1.00 46.30 ? 45  ILE B C     1 
ATOM   2701 O  O     . ILE B 1 45  ? 84.397  73.352  91.704  1.00 46.30 ? 45  ILE B O     1 
ATOM   2702 C  CB    . ILE B 1 45  ? 81.764  72.896  90.042  1.00 46.30 ? 45  ILE B CB    1 
ATOM   2703 C  CG1   . ILE B 1 45  ? 80.625  73.250  90.992  1.00 46.30 ? 45  ILE B CG1   1 
ATOM   2704 C  CG2   . ILE B 1 45  ? 82.391  71.569  90.410  1.00 46.30 ? 45  ILE B CG2   1 
ATOM   2705 C  CD1   . ILE B 1 45  ? 79.417  72.384  90.838  1.00 46.30 ? 45  ILE B CD1   1 
ATOM   2706 N  N     . PRO B 1 46  ? 83.156  75.153  92.215  1.00 46.31 ? 46  PRO B N     1 
ATOM   2707 C  CA    . PRO B 1 46  ? 83.760  75.293  93.544  1.00 46.31 ? 46  PRO B CA    1 
ATOM   2708 C  C     . PRO B 1 46  ? 83.537  74.107  94.465  1.00 46.31 ? 46  PRO B C     1 
ATOM   2709 O  O     . PRO B 1 46  ? 82.557  73.372  94.353  1.00 46.31 ? 46  PRO B O     1 
ATOM   2710 C  CB    . PRO B 1 46  ? 83.060  76.524  94.117  1.00 46.31 ? 46  PRO B CB    1 
ATOM   2711 C  CG    . PRO B 1 46  ? 82.655  77.269  93.000  1.00 46.31 ? 46  PRO B CG    1 
ATOM   2712 C  CD    . PRO B 1 46  ? 82.309  76.304  91.915  1.00 46.31 ? 46  PRO B CD    1 
ATOM   2713 N  N     . GLN B 1 47  ? 84.481  73.927  95.387  1.00 49.06 ? 47  GLN B N     1 
ATOM   2714 C  CA    . GLN B 1 47  ? 84.361  72.887  96.406  1.00 49.06 ? 47  GLN B CA    1 
ATOM   2715 C  C     . GLN B 1 47  ? 83.144  73.118  97.294  1.00 49.06 ? 47  GLN B C     1 
ATOM   2716 O  O     . GLN B 1 47  ? 82.593  72.171  97.852  1.00 49.06 ? 47  GLN B O     1 
ATOM   2717 C  CB    . GLN B 1 47  ? 85.642  72.842  97.224  1.00 49.06 ? 47  GLN B CB    1 
ATOM   2718 C  CG    . GLN B 1 47  ? 85.773  71.679  98.179  1.00 49.06 ? 47  GLN B CG    1 
ATOM   2719 C  CD    . GLN B 1 47  ? 87.068  71.763  98.936  1.00 49.06 ? 47  GLN B CD    1 
ATOM   2720 O  OE1   . GLN B 1 47  ? 87.937  70.909  98.794  1.00 49.06 ? 47  GLN B OE1   1 
ATOM   2721 N  NE2   . GLN B 1 47  ? 87.218  72.814  99.736  1.00 49.06 ? 47  GLN B NE2   1 
ATOM   2722 N  N     . LYS B 1 48  ? 82.741  74.378  97.460  1.00 51.53 ? 48  LYS B N     1 
ATOM   2723 C  CA    . LYS B 1 48  ? 81.540  74.734  98.214  1.00 51.53 ? 48  LYS B CA    1 
ATOM   2724 C  C     . LYS B 1 48  ? 80.320  73.944  97.762  1.00 51.53 ? 48  LYS B C     1 
ATOM   2725 O  O     . LYS B 1 48  ? 79.541  73.462  98.591  1.00 51.53 ? 48  LYS B O     1 
ATOM   2726 C  CB    . LYS B 1 48  ? 81.260  76.226  98.031  1.00 51.53 ? 48  LYS B CB    1 
ATOM   2727 C  CG    . LYS B 1 48  ? 80.027  76.748  98.733  1.00 51.53 ? 48  LYS B CG    1 
ATOM   2728 C  CD    . LYS B 1 48  ? 79.773  78.216  98.383  1.00 51.53 ? 48  LYS B CD    1 
ATOM   2729 C  CE    . LYS B 1 48  ? 80.813  79.151  98.972  1.00 51.53 ? 48  LYS B CE    1 
ATOM   2730 N  NZ    . LYS B 1 48  ? 80.472  80.579  98.736  1.00 51.53 ? 48  LYS B NZ    1 
ATOM   2731 N  N     . TYR B 1 49  ? 80.144  73.790  96.450  1.00 53.57 ? 49  TYR B N     1 
ATOM   2732 C  CA    . TYR B 1 49  ? 78.998  73.091  95.880  1.00 53.57 ? 49  TYR B CA    1 
ATOM   2733 C  C     . TYR B 1 49  ? 79.238  71.613  95.642  1.00 53.57 ? 49  TYR B C     1 
ATOM   2734 O  O     . TYR B 1 49  ? 78.285  70.833  95.678  1.00 53.57 ? 49  TYR B O     1 
ATOM   2735 C  CB    . TYR B 1 49  ? 78.569  73.776  94.580  1.00 53.57 ? 49  TYR B CB    1 
ATOM   2736 C  CG    . TYR B 1 49  ? 78.175  75.201  94.832  1.00 53.57 ? 49  TYR B CG    1 
ATOM   2737 C  CD1   . TYR B 1 49  ? 77.109  75.499  95.653  1.00 53.57 ? 49  TYR B CD1   1 
ATOM   2738 C  CD2   . TYR B 1 49  ? 78.904  76.247  94.309  1.00 53.57 ? 49  TYR B CD2   1 
ATOM   2739 C  CE1   . TYR B 1 49  ? 76.737  76.793  95.891  1.00 53.57 ? 49  TYR B CE1   1 
ATOM   2740 C  CE2   . TYR B 1 49  ? 78.561  77.541  94.567  1.00 53.57 ? 49  TYR B CE2   1 
ATOM   2741 C  CZ    . TYR B 1 49  ? 77.471  77.813  95.356  1.00 53.57 ? 49  TYR B CZ    1 
ATOM   2742 O  OH    . TYR B 1 49  ? 77.131  79.113  95.643  1.00 53.57 ? 49  TYR B OH    1 
ATOM   2743 N  N     . ALA B 1 50  ? 80.466  71.212  95.361  1.00 54.93 ? 50  ALA B N     1 
ATOM   2744 C  CA    . ALA B 1 50  ? 80.777  69.814  95.102  1.00 54.93 ? 50  ALA B CA    1 
ATOM   2745 C  C     . ALA B 1 50  ? 81.054  68.978  96.344  1.00 54.93 ? 50  ALA B C     1 
ATOM   2746 O  O     . ALA B 1 50  ? 80.942  67.754  96.270  1.00 54.93 ? 50  ALA B O     1 
ATOM   2747 C  CB    . ALA B 1 50  ? 81.974  69.709  94.164  1.00 54.93 ? 50  ALA B CB    1 
ATOM   2748 N  N     . ALA B 1 51  ? 81.444  69.581  97.463  1.00 60.23 ? 51  ALA B N     1 
ATOM   2749 C  CA    . ALA B 1 51  ? 81.779  68.798  98.655  1.00 60.23 ? 51  ALA B CA    1 
ATOM   2750 C  C     . ALA B 1 51  ? 80.690  67.830  99.115  1.00 60.23 ? 51  ALA B C     1 
ATOM   2751 O  O     . ALA B 1 51  ? 81.037  66.690  99.478  1.00 60.23 ? 51  ALA B O     1 
ATOM   2752 C  CB    . ALA B 1 51  ? 82.167  69.754  99.792  1.00 60.23 ? 51  ALA B CB    1 
ATOM   2753 N  N     . PRO B 1 52  ? 79.401  68.191  99.140  1.00 61.39 ? 52  PRO B N     1 
ATOM   2754 C  CA    . PRO B 1 52  ? 78.371  67.202  99.491  1.00 61.39 ? 52  PRO B CA    1 
ATOM   2755 C  C     . PRO B 1 52  ? 78.432  65.939  98.659  1.00 61.39 ? 52  PRO B C     1 
ATOM   2756 O  O     . PRO B 1 52  ? 78.169  64.845  99.168  1.00 61.39 ? 52  PRO B O     1 
ATOM   2757 C  CB    . PRO B 1 52  ? 77.067  67.967  99.244  1.00 61.39 ? 52  PRO B CB    1 
ATOM   2758 C  CG    . PRO B 1 52  ? 77.428  69.386  99.487  1.00 61.39 ? 52  PRO B CG    1 
ATOM   2759 C  CD    . PRO B 1 52  ? 78.812  69.527  98.948  1.00 61.39 ? 52  PRO B CD    1 
ATOM   2760 N  N     . PHE B 1 53  ? 78.799  66.064  97.391  1.00 60.78 ? 53  PHE B N     1 
ATOM   2761 C  CA    . PHE B 1 53  ? 78.906  64.926  96.489  1.00 60.78 ? 53  PHE B CA    1 
ATOM   2762 C  C     . PHE B 1 53  ? 80.180  64.137  96.751  1.00 60.78 ? 53  PHE B C     1 
ATOM   2763 O  O     . PHE B 1 53  ? 80.167  62.906  96.703  1.00 60.78 ? 53  PHE B O     1 
ATOM   2764 C  CB    . PHE B 1 53  ? 78.833  65.412  95.043  1.00 60.78 ? 53  PHE B CB    1 
ATOM   2765 C  CG    . PHE B 1 53  ? 77.511  66.020  94.680  1.00 60.78 ? 53  PHE B CG    1 
ATOM   2766 C  CD1   . PHE B 1 53  ? 76.484  65.235  94.199  1.00 60.78 ? 53  PHE B CD1   1 
ATOM   2767 C  CD2   . PHE B 1 53  ? 77.283  67.375  94.863  1.00 60.78 ? 53  PHE B CD2   1 
ATOM   2768 C  CE1   . PHE B 1 53  ? 75.275  65.791  93.876  1.00 60.78 ? 53  PHE B CE1   1 
ATOM   2769 C  CE2   . PHE B 1 53  ? 76.066  67.941  94.545  1.00 60.78 ? 53  PHE B CE2   1 
ATOM   2770 C  CZ    . PHE B 1 53  ? 75.063  67.153  94.051  1.00 60.78 ? 53  PHE B CZ    1 
ATOM   2771 N  N     . ILE B 1 54  ? 81.298  64.826  96.978  1.00 61.18 ? 54  ILE B N     1 
ATOM   2772 C  CA    . ILE B 1 54  ? 82.554  64.140  97.266  1.00 61.18 ? 54  ILE B CA    1 
ATOM   2773 C  C     . ILE B 1 54  ? 82.431  63.285  98.527  1.00 61.18 ? 54  ILE B C     1 
ATOM   2774 O  O     . ILE B 1 54  ? 82.950  62.163  98.580  1.00 61.18 ? 54  ILE B O     1 
ATOM   2775 C  CB    . ILE B 1 54  ? 83.699  65.163  97.405  1.00 61.18 ? 54  ILE B CB    1 
ATOM   2776 C  CG1   . ILE B 1 54  ? 83.800  66.083  96.185  1.00 61.18 ? 54  ILE B CG1   1 
ATOM   2777 C  CG2   . ILE B 1 54  ? 85.018  64.458  97.552  1.00 61.18 ? 54  ILE B CG2   1 
ATOM   2778 C  CD1   . ILE B 1 54  ? 84.097  65.373  94.904  1.00 61.18 ? 54  ILE B CD1   1 
ATOM   2779 N  N     . GLU B 1 55  ? 81.742  63.790  99.560  1.00 66.37 ? 55  GLU B N     1 
ATOM   2780 C  CA    . GLU B 1 55  ? 81.592  63.006  100.790 1.00 66.37 ? 55  GLU B CA    1 
ATOM   2781 C  C     . GLU B 1 55  ? 80.758  61.738  100.636 1.00 66.37 ? 55  GLU B C     1 
ATOM   2782 O  O     . GLU B 1 55  ? 80.814  60.881  101.517 1.00 66.37 ? 55  GLU B O     1 
ATOM   2783 C  CB    . GLU B 1 55  ? 80.972  63.823  101.923 1.00 66.37 ? 55  GLU B CB    1 
ATOM   2784 C  CG    . GLU B 1 55  ? 81.870  64.839  102.577 1.00 66.37 ? 55  GLU B CG    1 
ATOM   2785 C  CD    . GLU B 1 55  ? 81.174  65.543  103.723 1.00 66.37 ? 55  GLU B CD    1 
ATOM   2786 O  OE1   . GLU B 1 55  ? 79.969  65.283  103.934 1.00 66.37 ? 55  GLU B OE1   1 
ATOM   2787 O  OE2   . GLU B 1 55  ? 81.827  66.358  104.409 1.00 66.37 ? 55  GLU B OE2   1 
ATOM   2788 N  N     . VAL B 1 56  ? 79.986  61.590  99.565  1.00 64.42 ? 56  VAL B N     1 
ATOM   2789 C  CA    . VAL B 1 56  ? 79.154  60.408  99.361  1.00 64.42 ? 56  VAL B CA    1 
ATOM   2790 C  C     . VAL B 1 56  ? 79.667  59.539  98.221  1.00 64.42 ? 56  VAL B C     1 
ATOM   2791 O  O     . VAL B 1 56  ? 78.990  58.590  97.816  1.00 64.42 ? 56  VAL B O     1 
ATOM   2792 C  CB    . VAL B 1 56  ? 77.678  60.783  99.161  1.00 64.42 ? 56  VAL B CB    1 
ATOM   2793 C  CG1   . VAL B 1 56  ? 77.230  61.742  100.247 1.00 64.42 ? 56  VAL B CG1   1 
ATOM   2794 C  CG2   . VAL B 1 56  ? 77.475  61.400  97.805  1.00 64.42 ? 56  VAL B CG2   1 
ATOM   2795 N  N     . GLY B 1 57  ? 80.853  59.839  97.700  1.00 63.40 ? 57  GLY B N     1 
ATOM   2796 C  CA    . GLY B 1 57  ? 81.472  59.105  96.614  1.00 63.40 ? 57  GLY B CA    1 
ATOM   2797 C  C     . GLY B 1 57  ? 80.971  59.438  95.232  1.00 63.40 ? 57  GLY B C     1 
ATOM   2798 O  O     . GLY B 1 57  ? 81.356  58.763  94.273  1.00 63.40 ? 57  GLY B O     1 
ATOM   2799 N  N     . ALA B 1 58  ? 80.151  60.468  95.091  1.00 61.96 ? 58  ALA B N     1 
ATOM   2800 C  CA    . ALA B 1 58  ? 79.679  60.892  93.781  1.00 61.96 ? 58  ALA B CA    1 
ATOM   2801 C  C     . ALA B 1 58  ? 80.824  61.610  93.079  1.00 61.96 ? 58  ALA B C     1 
ATOM   2802 O  O     . ALA B 1 58  ? 81.186  62.726  93.458  1.00 61.96 ? 58  ALA B O     1 
ATOM   2803 C  CB    . ALA B 1 58  ? 78.462  61.797  93.920  1.00 61.96 ? 58  ALA B CB    1 
ATOM   2804 N  N     . LYS B 1 59  ? 81.407  60.968  92.073  1.00 56.57 ? 59  LYS B N     1 
ATOM   2805 C  CA    . LYS B 1 59  ? 82.579  61.520  91.409  1.00 56.57 ? 59  LYS B CA    1 
ATOM   2806 C  C     . LYS B 1 59  ? 82.244  62.842  90.727  1.00 56.57 ? 59  LYS B C     1 
ATOM   2807 O  O     . LYS B 1 59  ? 81.228  62.970  90.043  1.00 56.57 ? 59  LYS B O     1 
ATOM   2808 C  CB    . LYS B 1 59  ? 83.113  60.510  90.393  1.00 56.57 ? 59  LYS B CB    1 
ATOM   2809 C  CG    . LYS B 1 59  ? 83.348  59.145  91.011  1.00 56.57 ? 59  LYS B CG    1 
ATOM   2810 C  CD    . LYS B 1 59  ? 84.320  58.236  90.259  1.00 56.57 ? 59  LYS B CD    1 
ATOM   2811 C  CE    . LYS B 1 59  ? 85.750  58.671  90.433  1.00 56.57 ? 59  LYS B CE    1 
ATOM   2812 N  NZ    . LYS B 1 59  ? 86.698  57.653  89.909  1.00 56.57 ? 59  LYS B NZ    1 
ATOM   2813 N  N     . VAL B 1 60  ? 83.109  63.827  90.913  1.00 50.64 ? 60  VAL B N     1 
ATOM   2814 C  CA    . VAL B 1 60  ? 82.975  65.124  90.273  1.00 50.64 ? 60  VAL B CA    1 
ATOM   2815 C  C     . VAL B 1 60  ? 84.193  65.290  89.393  1.00 50.64 ? 60  VAL B C     1 
ATOM   2816 O  O     . VAL B 1 60  ? 85.325  65.204  89.876  1.00 50.64 ? 60  VAL B O     1 
ATOM   2817 C  CB    . VAL B 1 60  ? 82.865  66.269  91.292  1.00 50.64 ? 60  VAL B CB    1 
ATOM   2818 C  CG1   . VAL B 1 60  ? 82.655  67.587  90.588  1.00 50.64 ? 60  VAL B CG1   1 
ATOM   2819 C  CG2   . VAL B 1 60  ? 81.734  66.008  92.243  1.00 50.64 ? 60  VAL B CG2   1 
ATOM   2820 N  N     . LEU B 1 61  ? 83.966  65.471  88.101  1.00 47.19 ? 61  LEU B N     1 
ATOM   2821 C  CA    . LEU B 1 61  ? 85.029  65.639  87.128  1.00 47.19 ? 61  LEU B CA    1 
ATOM   2822 C  C     . LEU B 1 61  ? 84.968  67.071  86.625  1.00 47.19 ? 61  LEU B C     1 
ATOM   2823 O  O     . LEU B 1 61  ? 83.890  67.576  86.305  1.00 47.19 ? 61  LEU B O     1 
ATOM   2824 C  CB    . LEU B 1 61  ? 84.883  64.646  85.974  1.00 47.19 ? 61  LEU B CB    1 
ATOM   2825 C  CG    . LEU B 1 61  ? 84.706  63.183  86.370  1.00 47.19 ? 61  LEU B CG    1 
ATOM   2826 C  CD1   . LEU B 1 61  ? 84.620  62.287  85.142  1.00 47.19 ? 61  LEU B CD1   1 
ATOM   2827 C  CD2   . LEU B 1 61  ? 85.813  62.707  87.296  1.00 47.19 ? 61  LEU B CD2   1 
ATOM   2828 N  N     . ARG B 1 62  ? 86.119  67.721  86.582  1.00 46.59 ? 62  ARG B N     1 
ATOM   2829 C  CA    . ARG B 1 62  ? 86.238  69.103  86.158  1.00 46.59 ? 62  ARG B CA    1 
ATOM   2830 C  C     . ARG B 1 62  ? 87.255  69.246  85.040  1.00 46.59 ? 62  ARG B C     1 
ATOM   2831 O  O     . ARG B 1 62  ? 88.176  68.441  84.905  1.00 46.59 ? 62  ARG B O     1 
ATOM   2832 C  CB    . ARG B 1 62  ? 86.574  70.000  87.358  1.00 46.59 ? 62  ARG B CB    1 
ATOM   2833 C  CG    . ARG B 1 62  ? 87.701  69.481  88.222  1.00 46.59 ? 62  ARG B CG    1 
ATOM   2834 C  CD    . ARG B 1 62  ? 88.405  70.569  88.999  1.00 46.59 ? 62  ARG B CD    1 
ATOM   2835 N  NE    . ARG B 1 62  ? 87.523  71.361  89.843  1.00 46.59 ? 62  ARG B NE    1 
ATOM   2836 C  CZ    . ARG B 1 62  ? 87.935  72.076  90.877  1.00 46.59 ? 62  ARG B CZ    1 
ATOM   2837 N  NH1   . ARG B 1 62  ? 89.172  72.000  91.320  1.00 46.59 ? 62  ARG B NH1   1 
ATOM   2838 N  NH2   . ARG B 1 62  ? 87.080  72.883  91.484  1.00 46.59 ? 62  ARG B NH2   1 
ATOM   2839 N  N     . CYS B 1 63  ? 87.060  70.281  84.234  1.00 47.06 ? 63  CYS B N     1 
ATOM   2840 C  CA    . CYS B 1 63  ? 87.938  70.614  83.129  1.00 47.06 ? 63  CYS B CA    1 
ATOM   2841 C  C     . CYS B 1 63  ? 88.270  72.097  83.171  1.00 47.06 ? 63  CYS B C     1 
ATOM   2842 O  O     . CYS B 1 63  ? 87.614  72.879  83.856  1.00 47.06 ? 63  CYS B O     1 
ATOM   2843 C  CB    . CYS B 1 63  ? 87.307  70.263  81.784  1.00 47.06 ? 63  CYS B CB    1 
ATOM   2844 S  SG    . CYS B 1 63  ? 85.960  71.341  81.300  1.00 47.06 ? 63  CYS B SG    1 
ATOM   2845 N  N     . SER B 1 64  ? 89.324  72.467  82.451  1.00 47.57 ? 64  SER B N     1 
ATOM   2846 C  CA    . SER B 1 64  ? 89.776  73.850  82.404  1.00 47.57 ? 64  SER B CA    1 
ATOM   2847 C  C     . SER B 1 64  ? 88.690  74.790  81.896  1.00 47.57 ? 64  SER B C     1 
ATOM   2848 O  O     . SER B 1 64  ? 87.897  74.436  81.028  1.00 47.57 ? 64  SER B O     1 
ATOM   2849 C  CB    . SER B 1 64  ? 91.009  73.950  81.520  1.00 47.57 ? 64  SER B CB    1 
ATOM   2850 O  OG    . SER B 1 64  ? 91.428  75.293  81.433  1.00 47.57 ? 64  SER B OG    1 
ATOM   2851 N  N     . THR B 1 65  ? 88.655  76.001  82.443  1.00 47.63 ? 65  THR B N     1 
ATOM   2852 C  CA    . THR B 1 65  ? 87.691  76.993  81.983  1.00 47.63 ? 65  THR B CA    1 
ATOM   2853 C  C     . THR B 1 65  ? 87.925  77.393  80.534  1.00 47.63 ? 65  THR B C     1 
ATOM   2854 O  O     . THR B 1 65  ? 87.075  78.056  79.935  1.00 47.63 ? 65  THR B O     1 
ATOM   2855 C  CB    . THR B 1 65  ? 87.745  78.239  82.859  1.00 47.63 ? 65  THR B CB    1 
ATOM   2856 O  OG1   . THR B 1 65  ? 89.050  78.806  82.788  1.00 47.63 ? 65  THR B OG1   1 
ATOM   2857 C  CG2   . THR B 1 65  ? 87.489  77.878  84.287  1.00 47.63 ? 65  THR B CG2   1 
ATOM   2858 N  N     . ASN B 1 66  ? 89.083  77.067  79.986  1.00 49.95 ? 66  ASN B N     1 
ATOM   2859 C  CA    . ASN B 1 66  ? 89.410  77.319  78.592  1.00 49.95 ? 66  ASN B CA    1 
ATOM   2860 C  C     . ASN B 1 66  ? 89.056  76.184  77.638  1.00 49.95 ? 66  ASN B C     1 
ATOM   2861 O  O     . ASN B 1 66  ? 89.104  76.396  76.428  1.00 49.95 ? 66  ASN B O     1 
ATOM   2862 C  CB    . ASN B 1 66  ? 90.891  77.632  78.496  1.00 49.95 ? 66  ASN B CB    1 
ATOM   2863 C  CG    . ASN B 1 66  ? 91.221  78.955  79.102  1.00 49.95 ? 66  ASN B CG    1 
ATOM   2864 O  OD1   . ASN B 1 66  ? 90.630  79.970  78.757  1.00 49.95 ? 66  ASN B OD1   1 
ATOM   2865 N  ND2   . ASN B 1 66  ? 92.113  78.944  80.074  1.00 49.95 ? 66  ASN B ND2   1 
ATOM   2866 N  N     . ALA B 1 67  ? 88.735  74.991  78.140  1.00 53.02 ? 67  ALA B N     1 
ATOM   2867 C  CA    . ALA B 1 67  ? 88.466  73.848  77.269  1.00 53.02 ? 67  ALA B CA    1 
ATOM   2868 C  C     . ALA B 1 67  ? 87.320  74.113  76.296  1.00 53.02 ? 67  ALA B C     1 
ATOM   2869 O  O     . ALA B 1 67  ? 87.455  73.885  75.089  1.00 53.02 ? 67  ALA B O     1 
ATOM   2870 C  CB    . ALA B 1 67  ? 88.183  72.606  78.116  1.00 53.02 ? 67  ALA B CB    1 
ATOM   2871 N  N     . THR B 1 68  ? 86.209  74.650  76.784  1.00 57.36 ? 68  THR B N     1 
ATOM   2872 C  CA    . THR B 1 68  ? 85.096  74.974  75.895  1.00 57.36 ? 68  THR B CA    1 
ATOM   2873 C  C     . THR B 1 68  ? 85.412  76.164  74.995  1.00 57.36 ? 68  THR B C     1 
ATOM   2874 O  O     . THR B 1 68  ? 85.064  76.165  73.806  1.00 57.36 ? 68  THR B O     1 
ATOM   2875 C  CB    . THR B 1 68  ? 83.851  75.247  76.739  1.00 57.36 ? 68  THR B CB    1 
ATOM   2876 O  OG1   . THR B 1 68  ? 83.571  74.113  77.571  1.00 57.36 ? 68  THR B OG1   1 
ATOM   2877 C  CG2   . THR B 1 68  ? 82.665  75.597  75.889  1.00 57.36 ? 68  THR B CG2   1 
ATOM   2878 N  N     . ALA B 1 69  ? 86.077  77.182  75.537  1.00 59.54 ? 69  ALA B N     1 
ATOM   2879 C  CA    . ALA B 1 69  ? 86.422  78.349  74.733  1.00 59.54 ? 69  ALA B CA    1 
ATOM   2880 C  C     . ALA B 1 69  ? 87.332  77.970  73.576  1.00 59.54 ? 69  ALA B C     1 
ATOM   2881 O  O     . ALA B 1 69  ? 87.214  78.520  72.478  1.00 59.54 ? 69  ALA B O     1 
ATOM   2882 C  CB    . ALA B 1 69  ? 87.076  79.416  75.610  1.00 59.54 ? 69  ALA B CB    1 
ATOM   2883 N  N     . ASP B 1 70  ? 88.252  77.034  73.803  1.00 63.59 ? 70  ASP B N     1 
ATOM   2884 C  CA    . ASP B 1 70  ? 89.134  76.595  72.733  1.00 63.59 ? 70  ASP B CA    1 
ATOM   2885 C  C     . ASP B 1 70  ? 88.484  75.570  71.820  1.00 63.59 ? 70  ASP B C     1 
ATOM   2886 O  O     . ASP B 1 70  ? 88.914  75.428  70.672  1.00 63.59 ? 70  ASP B O     1 
ATOM   2887 C  CB    . ASP B 1 70  ? 90.431  76.042  73.317  1.00 63.59 ? 70  ASP B CB    1 
ATOM   2888 C  CG    . ASP B 1 70  ? 91.370  77.141  73.778  1.00 63.59 ? 70  ASP B CG    1 
ATOM   2889 O  OD1   . ASP B 1 70  ? 91.326  78.238  73.186  1.00 63.59 ? 70  ASP B OD1   1 
ATOM   2890 O  OD2   . ASP B 1 70  ? 92.157  76.912  74.720  1.00 63.59 ? 70  ASP B OD2   1 
ATOM   2891 N  N     . ALA B 1 71  ? 87.456  74.863  72.288  1.00 65.88 ? 71  ALA B N     1 
ATOM   2892 C  CA    . ALA B 1 71  ? 86.753  73.952  71.395  1.00 65.88 ? 71  ALA B CA    1 
ATOM   2893 C  C     . ALA B 1 71  ? 85.927  74.739  70.391  1.00 65.88 ? 71  ALA B C     1 
ATOM   2894 O  O     . ALA B 1 71  ? 85.807  74.350  69.226  1.00 65.88 ? 71  ALA B O     1 
ATOM   2895 C  CB    . ALA B 1 71  ? 85.872  72.994  72.192  1.00 65.88 ? 71  ALA B CB    1 
ATOM   2896 N  N     . ARG B 1 72  ? 85.376  75.868  70.823  1.00 68.74 ? 72  ARG B N     1 
ATOM   2897 C  CA    . ARG B 1 72  ? 84.581  76.720  69.946  1.00 68.74 ? 72  ARG B CA    1 
ATOM   2898 C  C     . ARG B 1 72  ? 85.398  77.408  68.855  1.00 68.74 ? 72  ARG B C     1 
ATOM   2899 O  O     . ARG B 1 72  ? 84.805  78.051  67.985  1.00 68.74 ? 72  ARG B O     1 
ATOM   2900 C  CB    . ARG B 1 72  ? 83.861  77.757  70.799  1.00 68.74 ? 72  ARG B CB    1 
ATOM   2901 C  CG    . ARG B 1 72  ? 82.690  77.146  71.531  1.00 68.74 ? 72  ARG B CG    1 
ATOM   2902 C  CD    . ARG B 1 72  ? 82.045  78.086  72.524  1.00 68.74 ? 72  ARG B CD    1 
ATOM   2903 N  NE    . ARG B 1 72  ? 80.736  77.581  72.915  1.00 68.74 ? 72  ARG B NE    1 
ATOM   2904 C  CZ    . ARG B 1 72  ? 80.106  77.898  74.039  1.00 68.74 ? 72  ARG B CZ    1 
ATOM   2905 N  NH1   . ARG B 1 72  ? 80.694  78.612  74.986  1.00 68.74 ? 72  ARG B NH1   1 
ATOM   2906 N  NH2   . ARG B 1 72  ? 78.874  77.441  74.242  1.00 68.74 ? 72  ARG B NH2   1 
ATOM   2907 N  N     . LYS B 1 73  ? 86.728  77.286  68.862  1.00 70.71 ? 73  LYS B N     1 
ATOM   2908 C  CA    . LYS B 1 73  ? 87.541  77.896  67.816  1.00 70.71 ? 73  LYS B CA    1 
ATOM   2909 C  C     . LYS B 1 73  ? 87.444  77.144  66.495  1.00 70.71 ? 73  LYS B C     1 
ATOM   2910 O  O     . LYS B 1 73  ? 87.820  77.693  65.453  1.00 70.71 ? 73  LYS B O     1 
ATOM   2911 C  CB    . LYS B 1 73  ? 89.010  77.962  68.250  1.00 70.71 ? 73  LYS B CB    1 
ATOM   2912 C  CG    . LYS B 1 73  ? 89.286  78.653  69.593  1.00 70.71 ? 73  LYS B CG    1 
ATOM   2913 C  CD    . LYS B 1 73  ? 89.037  80.156  69.546  1.00 70.71 ? 73  LYS B CD    1 
ATOM   2914 C  CE    . LYS B 1 73  ? 89.029  80.789  70.955  1.00 70.71 ? 73  LYS B CE    1 
ATOM   2915 N  NZ    . LYS B 1 73  ? 90.349  80.758  71.667  1.00 70.71 ? 73  LYS B NZ    1 
ATOM   2916 N  N     . ASN B 1 74  ? 86.946  75.908  66.520  1.00 72.39 ? 74  ASN B N     1 
ATOM   2917 C  CA    . ASN B 1 74  ? 86.835  75.054  65.338  1.00 72.39 ? 74  ASN B CA    1 
ATOM   2918 C  C     . ASN B 1 74  ? 85.501  75.203  64.603  1.00 72.39 ? 74  ASN B C     1 
ATOM   2919 O  O     . ASN B 1 74  ? 85.451  75.672  63.464  1.00 72.39 ? 74  ASN B O     1 
ATOM   2920 C  CB    . ASN B 1 74  ? 87.029  73.593  65.747  1.00 72.39 ? 74  ASN B CB    1 
ATOM   2921 C  CG    . ASN B 1 74  ? 88.325  73.360  66.500  1.00 72.39 ? 74  ASN B CG    1 
ATOM   2922 O  OD1   . ASN B 1 74  ? 89.409  73.475  65.938  1.00 72.39 ? 74  ASN B OD1   1 
ATOM   2923 N  ND2   . ASN B 1 74  ? 88.217  73.031  67.779  1.00 72.39 ? 74  ASN B ND2   1 
ATOM   2924 N  N     . ASN B 1 86  ? 70.130  79.347  73.358  1.00 87.58 ? 86  ASN B N     1 
ATOM   2925 C  CA    . ASN B 1 86  ? 70.147  80.139  74.582  1.00 87.58 ? 86  ASN B CA    1 
ATOM   2926 C  C     . ASN B 1 86  ? 71.484  80.063  75.340  1.00 87.58 ? 86  ASN B C     1 
ATOM   2927 O  O     . ASN B 1 86  ? 72.344  79.234  75.032  1.00 87.58 ? 86  ASN B O     1 
ATOM   2928 C  CB    . ASN B 1 86  ? 68.968  79.736  75.489  1.00 87.58 ? 86  ASN B CB    1 
ATOM   2929 C  CG    . ASN B 1 86  ? 69.016  78.276  75.927  1.00 87.58 ? 86  ASN B CG    1 
ATOM   2930 O  OD1   . ASN B 1 86  ? 70.012  77.803  76.467  1.00 87.58 ? 86  ASN B OD1   1 
ATOM   2931 N  ND2   . ASN B 1 86  ? 67.913  77.571  75.726  1.00 87.58 ? 86  ASN B ND2   1 
ATOM   2932 N  N     . ASP B 1 87  ? 71.624  80.948  76.333  1.00 88.72 ? 87  ASP B N     1 
ATOM   2933 C  CA    . ASP B 1 87  ? 72.843  81.032  77.137  1.00 88.72 ? 87  ASP B CA    1 
ATOM   2934 C  C     . ASP B 1 87  ? 73.068  79.761  77.953  1.00 88.72 ? 87  ASP B C     1 
ATOM   2935 O  O     . ASP B 1 87  ? 74.216  79.398  78.237  1.00 88.72 ? 87  ASP B O     1 
ATOM   2936 C  CB    . ASP B 1 87  ? 72.752  82.277  78.035  1.00 88.72 ? 87  ASP B CB    1 
ATOM   2937 C  CG    . ASP B 1 87  ? 74.003  82.530  78.846  1.00 88.72 ? 87  ASP B CG    1 
ATOM   2938 O  OD1   . ASP B 1 87  ? 75.117  82.227  78.364  1.00 88.72 ? 87  ASP B OD1   1 
ATOM   2939 O  OD2   . ASP B 1 87  ? 73.869  83.043  79.975  1.00 88.72 ? 87  ASP B OD2   1 
ATOM   2940 N  N     . GLU B 1 88  ? 71.990  79.085  78.355  1.00 82.05 ? 88  GLU B N     1 
ATOM   2941 C  CA    . GLU B 1 88  ? 72.051  77.815  79.080  1.00 82.05 ? 88  GLU B CA    1 
ATOM   2942 C  C     . GLU B 1 88  ? 72.607  76.660  78.241  1.00 82.05 ? 88  GLU B C     1 
ATOM   2943 O  O     . GLU B 1 88  ? 72.966  75.617  78.811  1.00 82.05 ? 88  GLU B O     1 
ATOM   2944 C  CB    . GLU B 1 88  ? 70.667  77.486  79.651  1.00 82.05 ? 88  GLU B CB    1 
ATOM   2945 C  CG    . GLU B 1 88  ? 70.143  78.596  80.570  1.00 82.05 ? 88  GLU B CG    1 
ATOM   2946 C  CD    . GLU B 1 88  ? 68.774  78.319  81.171  1.00 82.05 ? 88  GLU B CD    1 
ATOM   2947 O  OE1   . GLU B 1 88  ? 67.965  77.600  80.549  1.00 82.05 ? 88  GLU B OE1   1 
ATOM   2948 O  OE2   . GLU B 1 88  ? 68.520  78.812  82.290  1.00 82.05 ? 88  GLU B OE2   1 
ATOM   2949 N  N     . ASN B 1 89  ? 72.726  76.832  76.918  1.00 78.84 ? 89  ASN B N     1 
ATOM   2950 C  CA    . ASN B 1 89  ? 73.289  75.786  76.063  1.00 78.84 ? 89  ASN B CA    1 
ATOM   2951 C  C     . ASN B 1 89  ? 74.684  75.349  76.491  1.00 78.84 ? 89  ASN B C     1 
ATOM   2952 O  O     . ASN B 1 89  ? 75.111  74.255  76.108  1.00 78.84 ? 89  ASN B O     1 
ATOM   2953 C  CB    . ASN B 1 89  ? 73.331  76.215  74.593  1.00 78.84 ? 89  ASN B CB    1 
ATOM   2954 C  CG    . ASN B 1 89  ? 71.976  76.102  73.906  1.00 78.84 ? 89  ASN B CG    1 
ATOM   2955 O  OD1   . ASN B 1 89  ? 71.134  75.303  74.305  1.00 78.84 ? 89  ASN B OD1   1 
ATOM   2956 N  ND2   . ASN B 1 89  ? 71.785  76.866  72.832  1.00 78.84 ? 89  ASN B ND2   1 
ATOM   2957 N  N     . ASP B 1 90  ? 75.433  76.186  77.214  1.00 73.15 ? 90  ASP B N     1 
ATOM   2958 C  CA    . ASP B 1 90  ? 76.766  75.768  77.634  1.00 73.15 ? 90  ASP B CA    1 
ATOM   2959 C  C     . ASP B 1 90  ? 76.726  74.520  78.511  1.00 73.15 ? 90  ASP B C     1 
ATOM   2960 O  O     . ASP B 1 90  ? 77.648  73.701  78.444  1.00 73.15 ? 90  ASP B O     1 
ATOM   2961 C  CB    . ASP B 1 90  ? 77.473  76.902  78.370  1.00 73.15 ? 90  ASP B CB    1 
ATOM   2962 C  CG    . ASP B 1 90  ? 77.894  78.029  77.445  1.00 73.15 ? 90  ASP B CG    1 
ATOM   2963 O  OD1   . ASP B 1 90  ? 77.225  78.242  76.409  1.00 73.15 ? 90  ASP B OD1   1 
ATOM   2964 O  OD2   . ASP B 1 90  ? 78.903  78.701  77.751  1.00 73.15 ? 90  ASP B OD2   1 
ATOM   2965 N  N     . SER B 1 91  ? 75.624  74.288  79.231  1.00 66.46 ? 91  SER B N     1 
ATOM   2966 C  CA    . SER B 1 91  ? 75.498  73.035  79.975  1.00 66.46 ? 91  SER B CA    1 
ATOM   2967 C  C     . SER B 1 91  ? 75.536  71.835  79.048  1.00 66.46 ? 91  SER B C     1 
ATOM   2968 O  O     . SER B 1 91  ? 76.030  70.768  79.426  1.00 66.46 ? 91  SER B O     1 
ATOM   2969 C  CB    . SER B 1 91  ? 74.213  73.016  80.791  1.00 66.46 ? 91  SER B CB    1 
ATOM   2970 O  OG    . SER B 1 91  ? 73.091  72.961  79.939  1.00 66.46 ? 91  SER B OG    1 
ATOM   2971 N  N     . LYS B 1 92  ? 74.993  71.987  77.842  1.00 67.44 ? 92  LYS B N     1 
ATOM   2972 C  CA    . LYS B 1 92  ? 75.038  70.925  76.846  1.00 67.44 ? 92  LYS B CA    1 
ATOM   2973 C  C     . LYS B 1 92  ? 76.431  70.775  76.259  1.00 67.44 ? 92  LYS B C     1 
ATOM   2974 O  O     . LYS B 1 92  ? 76.911  69.650  76.077  1.00 67.44 ? 92  LYS B O     1 
ATOM   2975 C  CB    . LYS B 1 92  ? 74.043  71.210  75.723  1.00 67.44 ? 92  LYS B CB    1 
ATOM   2976 C  CG    . LYS B 1 92  ? 72.643  71.563  76.180  1.00 67.44 ? 92  LYS B CG    1 
ATOM   2977 C  CD    . LYS B 1 92  ? 71.759  71.921  74.987  1.00 67.44 ? 92  LYS B CD    1 
ATOM   2978 C  CE    . LYS B 1 92  ? 70.374  72.355  75.439  1.00 67.44 ? 92  LYS B CE    1 
ATOM   2979 N  NZ    . LYS B 1 92  ? 69.558  72.918  74.330  1.00 67.44 ? 92  LYS B NZ    1 
ATOM   2980 N  N     . VAL B 1 93  ? 77.134  71.893  76.048  1.00 63.07 ? 93  VAL B N     1 
ATOM   2981 C  CA    . VAL B 1 93  ? 78.480  71.814  75.488  1.00 63.07 ? 93  VAL B CA    1 
ATOM   2982 C  C     . VAL B 1 93  ? 79.417  71.072  76.424  1.00 63.07 ? 93  VAL B C     1 
ATOM   2983 O  O     . VAL B 1 93  ? 80.206  70.228  75.985  1.00 63.07 ? 93  VAL B O     1 
ATOM   2984 C  CB    . VAL B 1 93  ? 79.007  73.221  75.165  1.00 63.07 ? 93  VAL B CB    1 
ATOM   2985 C  CG1   . VAL B 1 93  ? 80.302  73.127  74.380  1.00 63.07 ? 93  VAL B CG1   1 
ATOM   2986 C  CG2   . VAL B 1 93  ? 77.963  74.007  74.412  1.00 63.07 ? 93  VAL B CG2   1 
ATOM   2987 N  N     . ILE B 1 94  ? 79.293  71.305  77.728  1.00 59.89 ? 94  ILE B N     1 
ATOM   2988 C  CA    . ILE B 1 94  ? 80.111  70.556  78.668  1.00 59.89 ? 94  ILE B CA    1 
ATOM   2989 C  C     . ILE B 1 94  ? 79.819  69.076  78.519  1.00 59.89 ? 94  ILE B C     1 
ATOM   2990 O  O     . ILE B 1 94  ? 80.739  68.260  78.367  1.00 59.89 ? 94  ILE B O     1 
ATOM   2991 C  CB    . ILE B 1 94  ? 79.864  71.039  80.109  1.00 59.89 ? 94  ILE B CB    1 
ATOM   2992 C  CG1   . ILE B 1 94  ? 80.333  72.478  80.289  1.00 59.89 ? 94  ILE B CG1   1 
ATOM   2993 C  CG2   . ILE B 1 94  ? 80.584  70.160  81.101  1.00 59.89 ? 94  ILE B CG2   1 
ATOM   2994 C  CD1   . ILE B 1 94  ? 79.773  73.114  81.503  1.00 59.89 ? 94  ILE B CD1   1 
ATOM   2995 N  N     . TRP B 1 95  ? 78.538  68.733  78.380  1.00 61.49 ? 95  TRP B N     1 
ATOM   2996 C  CA    . TRP B 1 95  ? 78.160  67.340  78.198  1.00 61.49 ? 95  TRP B CA    1 
ATOM   2997 C  C     . TRP B 1 95  ? 78.783  66.793  76.921  1.00 61.49 ? 95  TRP B C     1 
ATOM   2998 O  O     . TRP B 1 95  ? 79.451  65.752  76.940  1.00 61.49 ? 95  TRP B O     1 
ATOM   2999 C  CB    . TRP B 1 95  ? 76.628  67.250  78.174  1.00 61.49 ? 95  TRP B CB    1 
ATOM   3000 C  CG    . TRP B 1 95  ? 76.019  65.863  78.215  1.00 61.49 ? 95  TRP B CG    1 
ATOM   3001 C  CD1   . TRP B 1 95  ? 75.560  65.212  79.319  1.00 61.49 ? 95  TRP B CD1   1 
ATOM   3002 C  CD2   . TRP B 1 95  ? 75.771  64.993  77.108  1.00 61.49 ? 95  TRP B CD2   1 
ATOM   3003 N  NE1   . TRP B 1 95  ? 75.065  63.986  78.975  1.00 61.49 ? 95  TRP B NE1   1 
ATOM   3004 C  CE2   . TRP B 1 95  ? 75.184  63.826  77.621  1.00 61.49 ? 95  TRP B CE2   1 
ATOM   3005 C  CE3   . TRP B 1 95  ? 76.001  65.082  75.733  1.00 61.49 ? 95  TRP B CE3   1 
ATOM   3006 C  CZ2   . TRP B 1 95  ? 74.826  62.757  76.815  1.00 61.49 ? 95  TRP B CZ2   1 
ATOM   3007 C  CZ3   . TRP B 1 95  ? 75.647  64.015  74.931  1.00 61.49 ? 95  TRP B CZ3   1 
ATOM   3008 C  CH2   . TRP B 1 95  ? 75.067  62.868  75.474  1.00 61.49 ? 95  TRP B CH2   1 
ATOM   3009 N  N     . ALA B 1 96  ? 78.734  67.581  75.851  1.00 58.50 ? 96  ALA B N     1 
ATOM   3010 C  CA    . ALA B 1 96  ? 79.321  67.151  74.592  1.00 58.50 ? 96  ALA B CA    1 
ATOM   3011 C  C     . ALA B 1 96  ? 80.822  66.963  74.719  1.00 58.50 ? 96  ALA B C     1 
ATOM   3012 O  O     . ALA B 1 96  ? 81.358  65.923  74.315  1.00 58.50 ? 96  ALA B O     1 
ATOM   3013 C  CB    . ALA B 1 96  ? 79.003  68.180  73.508  1.00 58.50 ? 96  ALA B CB    1 
ATOM   3014 N  N     . LEU B 1 97  ? 81.490  67.882  75.419  1.00 58.72 ? 97  LEU B N     1 
ATOM   3015 C  CA    . LEU B 1 97  ? 82.927  67.753  75.596  1.00 58.72 ? 97  LEU B CA    1 
ATOM   3016 C  C     . LEU B 1 97  ? 83.256  66.550  76.453  1.00 58.72 ? 97  LEU B C     1 
ATOM   3017 O  O     . LEU B 1 97  ? 84.259  65.875  76.212  1.00 58.72 ? 97  LEU B O     1 
ATOM   3018 C  CB    . LEU B 1 97  ? 83.515  69.022  76.202  1.00 58.72 ? 97  LEU B CB    1 
ATOM   3019 C  CG    . LEU B 1 97  ? 84.119  70.073  75.265  1.00 58.72 ? 97  LEU B CG    1 
ATOM   3020 C  CD1   . LEU B 1 97  ? 85.451  69.582  74.735  1.00 58.72 ? 97  LEU B CD1   1 
ATOM   3021 C  CD2   . LEU B 1 97  ? 83.175  70.432  74.128  1.00 58.72 ? 97  LEU B CD2   1 
ATOM   3022 N  N     . TYR B 1 98  ? 82.440  66.271  77.462  1.00 57.49 ? 98  TYR B N     1 
ATOM   3023 C  CA    . TYR B 1 98  ? 82.704  65.085  78.257  1.00 57.49 ? 98  TYR B CA    1 
ATOM   3024 C  C     . TYR B 1 98  ? 82.543  63.823  77.421  1.00 57.49 ? 98  TYR B C     1 
ATOM   3025 O  O     . TYR B 1 98  ? 83.274  62.850  77.618  1.00 57.49 ? 98  TYR B O     1 
ATOM   3026 C  CB    . TYR B 1 98  ? 81.792  65.024  79.475  1.00 57.49 ? 98  TYR B CB    1 
ATOM   3027 C  CG    . TYR B 1 98  ? 82.024  63.783  80.293  1.00 57.49 ? 98  TYR B CG    1 
ATOM   3028 C  CD1   . TYR B 1 98  ? 83.211  63.607  80.978  1.00 57.49 ? 98  TYR B CD1   1 
ATOM   3029 C  CD2   . TYR B 1 98  ? 81.082  62.773  80.354  1.00 57.49 ? 98  TYR B CD2   1 
ATOM   3030 C  CE1   . TYR B 1 98  ? 83.446  62.482  81.717  1.00 57.49 ? 98  TYR B CE1   1 
ATOM   3031 C  CE2   . TYR B 1 98  ? 81.310  61.627  81.096  1.00 57.49 ? 98  TYR B CE2   1 
ATOM   3032 C  CZ    . TYR B 1 98  ? 82.495  61.490  81.775  1.00 57.49 ? 98  TYR B CZ    1 
ATOM   3033 O  OH    . TYR B 1 98  ? 82.739  60.363  82.525  1.00 57.49 ? 98  TYR B OH    1 
ATOM   3034 N  N     . GLN B 1 99  ? 81.588  63.822  76.485  1.00 59.91 ? 99  GLN B N     1 
ATOM   3035 C  CA    . GLN B 1 99  ? 81.370  62.644  75.648  1.00 59.91 ? 99  GLN B CA    1 
ATOM   3036 C  C     . GLN B 1 99  ? 82.450  62.442  74.592  1.00 59.91 ? 99  GLN B C     1 
ATOM   3037 O  O     . GLN B 1 99  ? 82.876  61.308  74.353  1.00 59.91 ? 99  GLN B O     1 
ATOM   3038 C  CB    . GLN B 1 99  ? 79.989  62.724  74.997  1.00 59.91 ? 99  GLN B CB    1 
ATOM   3039 C  CG    . GLN B 1 99  ? 78.853  62.453  75.975  1.00 59.91 ? 99  GLN B CG    1 
ATOM   3040 C  CD    . GLN B 1 99  ? 78.885  61.027  76.489  1.00 59.91 ? 99  GLN B CD    1 
ATOM   3041 O  OE1   . GLN B 1 99  ? 79.564  60.175  75.922  1.00 59.91 ? 99  GLN B OE1   1 
ATOM   3042 N  NE2   . GLN B 1 99  ? 78.163  60.762  77.573  1.00 59.91 ? 99  GLN B NE2   1 
ATOM   3043 N  N     . THR B 1 100 ? 82.928  63.511  73.972  1.00 58.29 ? 100 THR B N     1 
ATOM   3044 C  CA    . THR B 1 100 ? 83.921  63.352  72.919  1.00 58.29 ? 100 THR B CA    1 
ATOM   3045 C  C     . THR B 1 100 ? 85.360  63.275  73.424  1.00 58.29 ? 100 THR B C     1 
ATOM   3046 O  O     . THR B 1 100 ? 86.154  62.499  72.885  1.00 58.29 ? 100 THR B O     1 
ATOM   3047 C  CB    . THR B 1 100 ? 83.781  64.502  71.918  1.00 58.29 ? 100 THR B CB    1 
ATOM   3048 O  OG1   . THR B 1 100 ? 83.811  65.748  72.615  1.00 58.29 ? 100 THR B OG1   1 
ATOM   3049 C  CG2   . THR B 1 100 ? 82.466  64.406  71.190  1.00 58.29 ? 100 THR B CG2   1 
ATOM   3050 N  N     . HIS B 1 101 ? 85.722  64.050  74.439  1.00 56.80 ? 101 HIS B N     1 
ATOM   3051 C  CA    . HIS B 1 101 ? 87.083  64.069  74.986  1.00 56.80 ? 101 HIS B CA    1 
ATOM   3052 C  C     . HIS B 1 101 ? 87.114  64.001  76.510  1.00 56.80 ? 101 HIS B C     1 
ATOM   3053 O  O     . HIS B 1 101 ? 87.471  64.973  77.177  1.00 56.80 ? 101 HIS B O     1 
ATOM   3054 C  CB    . HIS B 1 101 ? 87.868  65.274  74.479  1.00 56.80 ? 101 HIS B CB    1 
ATOM   3055 C  CG    . HIS B 1 101 ? 88.136  65.236  73.010  1.00 56.80 ? 101 HIS B CG    1 
ATOM   3056 N  ND1   . HIS B 1 101 ? 87.167  65.480  72.064  1.00 56.80 ? 101 HIS B ND1   1 
ATOM   3057 C  CD2   . HIS B 1 101 ? 89.258  64.914  72.324  1.00 56.80 ? 101 HIS B CD2   1 
ATOM   3058 C  CE1   . HIS B 1 101 ? 87.692  65.357  70.858  1.00 56.80 ? 101 HIS B CE1   1 
ATOM   3059 N  NE2   . HIS B 1 101 ? 88.959  65.007  70.989  1.00 56.80 ? 101 HIS B NE2   1 
ATOM   3060 N  N     . PRO B 1 102 ? 86.687  62.883  77.100  1.00 56.17 ? 102 PRO B N     1 
ATOM   3061 C  CA    . PRO B 1 102 ? 86.682  62.780  78.569  1.00 56.17 ? 102 PRO B CA    1 
ATOM   3062 C  C     . PRO B 1 102 ? 88.067  62.887  79.215  1.00 56.17 ? 102 PRO B C     1 
ATOM   3063 O  O     . PRO B 1 102 ? 88.144  63.030  80.439  1.00 56.17 ? 102 PRO B O     1 
ATOM   3064 C  CB    . PRO B 1 102 ? 86.073  61.397  78.820  1.00 56.17 ? 102 PRO B CB    1 
ATOM   3065 C  CG    . PRO B 1 102 ? 86.376  60.646  77.602  1.00 56.17 ? 102 PRO B CG    1 
ATOM   3066 C  CD    . PRO B 1 102 ? 86.309  61.614  76.470  1.00 56.17 ? 102 PRO B CD    1 
ATOM   3067 N  N     . GLU B 1 103 ? 89.152  62.831  78.445  1.00 55.54 ? 103 GLU B N     1 
ATOM   3068 C  CA    . GLU B 1 103 ? 90.492  62.982  79.005  1.00 55.54 ? 103 GLU B CA    1 
ATOM   3069 C  C     . GLU B 1 103 ? 90.752  64.400  79.504  1.00 55.54 ? 103 GLU B C     1 
ATOM   3070 O  O     . GLU B 1 103 ? 91.672  64.612  80.298  1.00 55.54 ? 103 GLU B O     1 
ATOM   3071 C  CB    . GLU B 1 103 ? 91.553  62.565  77.979  1.00 55.54 ? 103 GLU B CB    1 
ATOM   3072 C  CG    . GLU B 1 103 ? 91.634  63.448  76.736  1.00 55.54 ? 103 GLU B CG    1 
ATOM   3073 C  CD    . GLU B 1 103 ? 90.786  62.918  75.580  1.00 55.54 ? 103 GLU B CD    1 
ATOM   3074 O  OE1   . GLU B 1 103 ? 89.678  62.401  75.828  1.00 55.54 ? 103 GLU B OE1   1 
ATOM   3075 O  OE2   . GLU B 1 103 ? 91.228  63.030  74.414  1.00 55.54 ? 103 GLU B OE2   1 
ATOM   3076 N  N     . LEU B 1 104 ? 89.969  65.371  79.050  1.00 51.65 ? 104 LEU B N     1 
ATOM   3077 C  CA    . LEU B 1 104 ? 90.092  66.738  79.523  1.00 51.65 ? 104 LEU B CA    1 
ATOM   3078 C  C     . LEU B 1 104 ? 89.543  66.901  80.938  1.00 51.65 ? 104 LEU B C     1 
ATOM   3079 O  O     . LEU B 1 104 ? 89.786  67.931  81.573  1.00 51.65 ? 104 LEU B O     1 
ATOM   3080 C  CB    . LEU B 1 104 ? 89.342  67.669  78.581  1.00 51.65 ? 104 LEU B CB    1 
ATOM   3081 C  CG    . LEU B 1 104 ? 89.792  67.836  77.136  1.00 51.65 ? 104 LEU B CG    1 
ATOM   3082 C  CD1   . LEU B 1 104 ? 88.801  68.712  76.402  1.00 51.65 ? 104 LEU B CD1   1 
ATOM   3083 C  CD2   . LEU B 1 104 ? 91.163  68.441  77.044  1.00 51.65 ? 104 LEU B CD2   1 
ATOM   3084 N  N     . PHE B 1 105 ? 88.759  65.938  81.411  1.00 49.77 ? 105 PHE B N     1 
ATOM   3085 C  CA    . PHE B 1 105 ? 88.095  65.988  82.709  1.00 49.77 ? 105 PHE B CA    1 
ATOM   3086 C  C     . PHE B 1 105 ? 88.881  65.210  83.759  1.00 49.77 ? 105 PHE B C     1 
ATOM   3087 O  O     . PHE B 1 105 ? 89.198  64.037  83.561  1.00 49.77 ? 105 PHE B O     1 
ATOM   3088 C  CB    . PHE B 1 105 ? 86.667  65.467  82.548  1.00 49.77 ? 105 PHE B CB    1 
ATOM   3089 C  CG    . PHE B 1 105 ? 85.797  66.417  81.771  1.00 49.77 ? 105 PHE B CG    1 
ATOM   3090 C  CD1   . PHE B 1 105 ? 85.859  66.451  80.390  1.00 49.77 ? 105 PHE B CD1   1 
ATOM   3091 C  CD2   . PHE B 1 105 ? 84.997  67.336  82.413  1.00 49.77 ? 105 PHE B CD2   1 
ATOM   3092 C  CE1   . PHE B 1 105 ? 85.115  67.354  79.677  1.00 49.77 ? 105 PHE B CE1   1 
ATOM   3093 C  CE2   . PHE B 1 105 ? 84.246  68.232  81.696  1.00 49.77 ? 105 PHE B CE2   1 
ATOM   3094 C  CZ    . PHE B 1 105 ? 84.303  68.240  80.332  1.00 49.77 ? 105 PHE B CZ    1 
ATOM   3095 N  N     . ARG B 1 106 ? 89.193  65.874  84.874  1.00 46.35 ? 106 ARG B N     1 
ATOM   3096 C  CA    . ARG B 1 106 ? 89.988  65.326  85.968  1.00 46.35 ? 106 ARG B CA    1 
ATOM   3097 C  C     . ARG B 1 106 ? 89.190  65.316  87.265  1.00 46.35 ? 106 ARG B C     1 
ATOM   3098 O  O     . ARG B 1 106 ? 88.463  66.264  87.562  1.00 46.35 ? 106 ARG B O     1 
ATOM   3099 C  CB    . ARG B 1 106 ? 91.248  66.175  86.104  1.00 46.35 ? 106 ARG B CB    1 
ATOM   3100 C  CG    . ARG B 1 106 ? 92.261  65.849  85.035  1.00 46.35 ? 106 ARG B CG    1 
ATOM   3101 C  CD    . ARG B 1 106 ? 93.476  66.725  85.045  1.00 46.35 ? 106 ARG B CD    1 
ATOM   3102 N  NE    . ARG B 1 106 ? 93.125  68.036  84.514  1.00 46.35 ? 106 ARG B NE    1 
ATOM   3103 C  CZ    . ARG B 1 106 ? 93.624  68.562  83.404  1.00 46.35 ? 106 ARG B CZ    1 
ATOM   3104 N  NH1   . ARG B 1 106 ? 94.587  67.966  82.727  1.00 46.35 ? 106 ARG B NH1   1 
ATOM   3105 N  NH2   . ARG B 1 106 ? 93.132  69.712  82.957  1.00 46.35 ? 106 ARG B NH2   1 
ATOM   3106 N  N     . GLU B 1 107 ? 89.376  64.263  88.060  1.00 50.54 ? 107 GLU B N     1 
ATOM   3107 C  CA    . GLU B 1 107 ? 88.612  64.060  89.291  1.00 50.54 ? 107 GLU B CA    1 
ATOM   3108 C  C     . GLU B 1 107 ? 88.966  65.060  90.385  1.00 50.54 ? 107 GLU B C     1 
ATOM   3109 O  O     . GLU B 1 107 ? 90.104  65.097  90.858  1.00 50.54 ? 107 GLU B O     1 
ATOM   3110 C  CB    . GLU B 1 107 ? 88.842  62.635  89.777  1.00 50.54 ? 107 GLU B CB    1 
ATOM   3111 C  CG    . GLU B 1 107 ? 88.140  62.245  91.050  1.00 50.54 ? 107 GLU B CG    1 
ATOM   3112 C  CD    . GLU B 1 107 ? 88.291  60.767  91.327  1.00 50.54 ? 107 GLU B CD    1 
ATOM   3113 O  OE1   . GLU B 1 107 ? 88.634  60.031  90.380  1.00 50.54 ? 107 GLU B OE1   1 
ATOM   3114 O  OE2   . GLU B 1 107 ? 88.086  60.343  92.484  1.00 50.54 ? 107 GLU B OE2   1 
ATOM   3115 N  N     . MET B 1 108 ? 87.970  65.831  90.820  1.00 48.48 ? 108 MET B N     1 
ATOM   3116 C  CA    . MET B 1 108 ? 88.142  66.812  91.886  1.00 48.48 ? 108 MET B CA    1 
ATOM   3117 C  C     . MET B 1 108 ? 88.219  66.108  93.238  1.00 48.48 ? 108 MET B C     1 
ATOM   3118 O  O     . MET B 1 108 ? 87.470  65.168  93.506  1.00 48.48 ? 108 MET B O     1 
ATOM   3119 C  CB    . MET B 1 108 ? 87.002  67.826  91.870  1.00 48.48 ? 108 MET B CB    1 
ATOM   3120 C  CG    . MET B 1 108 ? 87.353  69.120  92.544  1.00 48.48 ? 108 MET B CG    1 
ATOM   3121 S  SD    . MET B 1 108 ? 85.989  70.229  92.909  1.00 48.48 ? 108 MET B SD    1 
ATOM   3122 C  CE    . MET B 1 108 ? 85.372  69.487  94.395  1.00 48.48 ? 108 MET B CE    1 
ATOM   3123 N  N     . LYS B 1 109 ? 89.145  66.540  94.083  1.00 46.40 ? 109 LYS B N     1 
ATOM   3124 C  CA    . LYS B 1 109 ? 89.347  65.946  95.398  1.00 46.40 ? 109 LYS B CA    1 
ATOM   3125 C  C     . LYS B 1 109 ? 89.257  67.005  96.490  1.00 46.40 ? 109 LYS B C     1 
ATOM   3126 O  O     . LYS B 1 109 ? 89.655  68.152  96.285  1.00 46.40 ? 109 LYS B O     1 
ATOM   3127 C  CB    . LYS B 1 109 ? 90.700  65.232  95.409  1.00 46.40 ? 109 LYS B CB    1 
ATOM   3128 C  CG    . LYS B 1 109 ? 90.680  64.022  94.486  1.00 46.40 ? 109 LYS B CG    1 
ATOM   3129 C  CD    . LYS B 1 109 ? 91.903  63.136  94.577  1.00 46.40 ? 109 LYS B CD    1 
ATOM   3130 C  CE    . LYS B 1 109 ? 93.115  63.839  93.968  1.00 46.40 ? 109 LYS B CE    1 
ATOM   3131 N  NZ    . LYS B 1 109 ? 94.360  63.030  94.050  1.00 46.40 ? 109 LYS B NZ    1 
ATOM   3132 N  N     . LEU B 1 110 ? 88.699  66.626  97.640  1.00 49.41 ? 110 LEU B N     1 
ATOM   3133 C  CA    . LEU B 1 110 ? 88.535  67.562  98.751  1.00 49.41 ? 110 LEU B CA    1 
ATOM   3134 C  C     . LEU B 1 110 ? 89.907  67.984  99.290  1.00 49.41 ? 110 LEU B C     1 
ATOM   3135 O  O     . LEU B 1 110 ? 90.766  67.137  99.552  1.00 49.41 ? 110 LEU B O     1 
ATOM   3136 C  CB    . LEU B 1 110 ? 87.674  66.910  99.828  1.00 49.41 ? 110 LEU B CB    1 
ATOM   3137 C  CG    . LEU B 1 110 ? 87.144  67.772  100.966 1.00 49.41 ? 110 LEU B CG    1 
ATOM   3138 C  CD1   . LEU B 1 110 ? 86.040  68.678  100.443 1.00 49.41 ? 110 LEU B CD1   1 
ATOM   3139 C  CD2   . LEU B 1 110 ? 86.621  66.906  102.090 1.00 49.41 ? 110 LEU B CD2   1 
ATOM   3140 N  N     . GLU B 1 111 ? 90.117  69.296  99.444  1.00 46.63 ? 111 GLU B N     1 
ATOM   3141 C  CA    . GLU B 1 111 ? 91.426  69.820  99.834  1.00 46.63 ? 111 GLU B CA    1 
ATOM   3142 C  C     . GLU B 1 111 ? 91.762  69.605  101.314 1.00 46.63 ? 111 GLU B C     1 
ATOM   3143 O  O     . GLU B 1 111 ? 90.873  69.509  102.164 1.00 46.63 ? 111 GLU B O     1 
ATOM   3144 C  CB    . GLU B 1 111 ? 91.496  71.316  99.516  1.00 46.63 ? 111 GLU B CB    1 
ATOM   3145 C  CG    . GLU B 1 111 ? 90.792  72.181  100.542 1.00 46.63 ? 111 GLU B CG    1 
ATOM   3146 C  CD    . GLU B 1 111 ? 90.672  73.639  100.127 1.00 46.63 ? 111 GLU B CD    1 
ATOM   3147 O  OE1   . GLU B 1 111 ? 91.591  74.174  99.474  1.00 46.63 ? 111 GLU B OE1   1 
ATOM   3148 O  OE2   . GLU B 1 111 ? 89.642  74.258  100.458 1.00 46.63 ? 111 GLU B OE2   1 
ATOM   3149 N  N     . PRO B 1 112 ? 93.055  69.510  101.639 1.00 38.74 ? 112 PRO B N     1 
ATOM   3150 C  CA    . PRO B 1 112 ? 93.455  69.398  103.036 1.00 38.74 ? 112 PRO B CA    1 
ATOM   3151 C  C     . PRO B 1 112 ? 93.350  70.736  103.745 1.00 38.74 ? 112 PRO B C     1 
ATOM   3152 O  O     . PRO B 1 112 ? 93.430  71.798  103.104 1.00 38.74 ? 112 PRO B O     1 
ATOM   3153 C  CB    . PRO B 1 112 ? 94.912  68.910  102.946 1.00 38.74 ? 112 PRO B CB    1 
ATOM   3154 C  CG    . PRO B 1 112 ? 95.394  69.468  101.683 1.00 38.74 ? 112 PRO B CG    1 
ATOM   3155 C  CD    . PRO B 1 112 ? 94.215  69.441  100.739 1.00 38.74 ? 112 PRO B CD    1 
ATOM   3156 N  N     . PRO B 1 113 ? 93.179  70.739  105.071 1.00 34.73 ? 113 PRO B N     1 
ATOM   3157 C  CA    . PRO B 1 113 ? 93.040  72.017  105.794 1.00 34.73 ? 113 PRO B CA    1 
ATOM   3158 C  C     . PRO B 1 113 ? 94.277  72.899  105.704 1.00 34.73 ? 113 PRO B C     1 
ATOM   3159 O  O     . PRO B 1 113 ? 94.182  74.127  105.894 1.00 34.73 ? 113 PRO B O     1 
ATOM   3160 C  CB    . PRO B 1 113 ? 92.747  71.573  107.234 1.00 34.73 ? 113 PRO B CB    1 
ATOM   3161 C  CG    . PRO B 1 113 ? 93.326  70.212  107.333 1.00 34.73 ? 113 PRO B CG    1 
ATOM   3162 C  CD    . PRO B 1 113 ? 93.127  69.589  105.984 1.00 34.73 ? 113 PRO B CD    1 
ATOM   3163 N  N     . LEU B 1 114 ? 95.432  72.308  105.405 1.00 31.21 ? 114 LEU B N     1 
ATOM   3164 C  CA    . LEU B 1 114 ? 96.643  73.082  105.183 1.00 31.21 ? 114 LEU B CA    1 
ATOM   3165 C  C     . LEU B 1 114 ? 96.438  74.138  104.102 1.00 31.21 ? 114 LEU B C     1 
ATOM   3166 O  O     . LEU B 1 114 ? 96.940  75.255  104.224 1.00 31.21 ? 114 LEU B O     1 
ATOM   3167 C  CB    . LEU B 1 114 ? 97.799  72.154  104.816 1.00 31.21 ? 114 LEU B CB    1 
ATOM   3168 C  CG    . LEU B 1 114 ? 99.092  72.847  104.394 1.00 31.21 ? 114 LEU B CG    1 
ATOM   3169 C  CD1   . LEU B 1 114 ? 99.640  73.715  105.505 1.00 31.21 ? 114 LEU B CD1   1 
ATOM   3170 C  CD2   . LEU B 1 114 ? 100.114 71.830  103.998 1.00 31.21 ? 114 LEU B CD2   1 
ATOM   3171 N  N     . SER B 1 115 ? 95.762  73.782  103.005 1.00 30.76 ? 115 SER B N     1 
ATOM   3172 C  CA    . SER B 1 115 ? 95.525  74.742  101.932 1.00 30.76 ? 115 SER B CA    1 
ATOM   3173 C  C     . SER B 1 115 ? 94.729  75.942  102.405 1.00 30.76 ? 115 SER B C     1 
ATOM   3174 O  O     . SER B 1 115 ? 94.976  77.063  101.953 1.00 30.76 ? 115 SER B O     1 
ATOM   3175 C  CB    . SER B 1 115 ? 94.781  74.073  100.780 1.00 30.76 ? 115 SER B CB    1 
ATOM   3176 O  OG    . SER B 1 115 ? 95.537  73.019  100.226 1.00 30.76 ? 115 SER B OG    1 
ATOM   3177 N  N     . SER B 1 116 ? 93.833  75.749  103.366 1.00 29.45 ? 116 SER B N     1 
ATOM   3178 C  CA    . SER B 1 116 ? 93.085  76.876  103.907 1.00 29.45 ? 116 SER B CA    1 
ATOM   3179 C  C     . SER B 1 116 ? 93.987  77.758  104.750 1.00 29.45 ? 116 SER B C     1 
ATOM   3180 O  O     . SER B 1 116 ? 93.969  78.983  104.610 1.00 29.45 ? 116 SER B O     1 
ATOM   3181 C  CB    . SER B 1 116 ? 91.877  76.394  104.708 1.00 29.45 ? 116 SER B CB    1 
ATOM   3182 O  OG    . SER B 1 116 ? 92.244  75.904  105.980 1.00 29.45 ? 116 SER B OG    1 
ATOM   3183 N  N     . TYR B 1 117 ? 94.777  77.156  105.646 1.00 28.47 ? 117 TYR B N     1 
ATOM   3184 C  CA    . TYR B 1 117 ? 95.678  77.981  106.453 1.00 28.47 ? 117 TYR B CA    1 
ATOM   3185 C  C     . TYR B 1 117 ? 96.690  78.719  105.590 1.00 28.47 ? 117 TYR B C     1 
ATOM   3186 O  O     . TYR B 1 117 ? 96.995  79.882  105.852 1.00 28.47 ? 117 TYR B O     1 
ATOM   3187 C  CB    . TYR B 1 117 ? 96.418  77.161  107.508 1.00 28.47 ? 117 TYR B CB    1 
ATOM   3188 C  CG    . TYR B 1 117 ? 95.567  76.432  108.496 1.00 28.47 ? 117 TYR B CG    1 
ATOM   3189 C  CD1   . TYR B 1 117 ? 94.628  77.106  109.260 1.00 28.47 ? 117 TYR B CD1   1 
ATOM   3190 C  CD2   . TYR B 1 117 ? 95.748  75.089  108.719 1.00 28.47 ? 117 TYR B CD2   1 
ATOM   3191 C  CE1   . TYR B 1 117 ? 93.862  76.448  110.182 1.00 28.47 ? 117 TYR B CE1   1 
ATOM   3192 C  CE2   . TYR B 1 117 ? 94.994  74.425  109.632 1.00 28.47 ? 117 TYR B CE2   1 
ATOM   3193 C  CZ    . TYR B 1 117 ? 94.047  75.106  110.366 1.00 28.47 ? 117 TYR B CZ    1 
ATOM   3194 O  OH    . TYR B 1 117 ? 93.293  74.416  111.288 1.00 28.47 ? 117 TYR B OH    1 
ATOM   3195 N  N     . TYR B 1 118 ? 97.243  78.061  104.574 1.00 24.20 ? 118 TYR B N     1 
ATOM   3196 C  CA    . TYR B 1 118 ? 98.188  78.733  103.686 1.00 24.20 ? 118 TYR B CA    1 
ATOM   3197 C  C     . TYR B 1 118 ? 97.520  79.857  102.901 1.00 24.20 ? 118 TYR B C     1 
ATOM   3198 O  O     . TYR B 1 118 ? 98.126  80.907  102.686 1.00 24.20 ? 118 TYR B O     1 
ATOM   3199 C  CB    . TYR B 1 118 ? 98.864  77.729  102.760 1.00 24.20 ? 118 TYR B CB    1 
ATOM   3200 C  CG    . TYR B 1 118 ? 99.851  78.364  101.816 1.00 24.20 ? 118 TYR B CG    1 
ATOM   3201 C  CD1   . TYR B 1 118 ? 101.123 78.708  102.239 1.00 24.20 ? 118 TYR B CD1   1 
ATOM   3202 C  CD2   . TYR B 1 118 ? 99.521  78.588  100.492 1.00 24.20 ? 118 TYR B CD2   1 
ATOM   3203 C  CE1   . TYR B 1 118 ? 102.002 79.323  101.388 1.00 24.20 ? 118 TYR B CE1   1 
ATOM   3204 C  CE2   . TYR B 1 118 ? 100.413 79.170  99.624  1.00 24.20 ? 118 TYR B CE2   1 
ATOM   3205 C  CZ    . TYR B 1 118 ? 101.641 79.547  100.082 1.00 24.20 ? 118 TYR B CZ    1 
ATOM   3206 O  OH    . TYR B 1 118 ? 102.541 80.060  99.201  1.00 24.20 ? 118 TYR B OH    1 
ATOM   3207 N  N     . ALA B 1 119 ? 96.298  79.645  102.424 1.00 22.49 ? 119 ALA B N     1 
ATOM   3208 C  CA    . ALA B 1 119 ? 95.565  80.710  101.751 1.00 22.49 ? 119 ALA B CA    1 
ATOM   3209 C  C     . ALA B 1 119 ? 95.338  81.904  102.669 1.00 22.49 ? 119 ALA B C     1 
ATOM   3210 O  O     . ALA B 1 119 ? 95.530  83.047  102.262 1.00 22.49 ? 119 ALA B O     1 
ATOM   3211 C  CB    . ALA B 1 119 ? 94.239  80.170  101.226 1.00 22.49 ? 119 ALA B CB    1 
ATOM   3212 N  N     . ILE B 1 120 ? 94.891  81.664  103.905 1.00 23.85 ? 120 ILE B N     1 
ATOM   3213 C  CA    . ILE B 1 120 ? 94.655  82.770  104.837 1.00 23.85 ? 120 ILE B CA    1 
ATOM   3214 C  C     . ILE B 1 120 ? 95.970  83.438  105.222 1.00 23.85 ? 120 ILE B C     1 
ATOM   3215 O  O     . ILE B 1 120 ? 96.038  84.658  105.394 1.00 23.85 ? 120 ILE B O     1 
ATOM   3216 C  CB    . ILE B 1 120 ? 93.878  82.287  106.078 1.00 23.85 ? 120 ILE B CB    1 
ATOM   3217 C  CG1   . ILE B 1 120 ? 92.602  81.567  105.674 1.00 23.85 ? 120 ILE B CG1   1 
ATOM   3218 C  CG2   . ILE B 1 120 ? 93.520  83.449  106.976 1.00 23.85 ? 120 ILE B CG2   1 
ATOM   3219 C  CD1   . ILE B 1 120 ? 92.174  80.521  106.659 1.00 23.85 ? 120 ILE B CD1   1 
ATOM   3220 N  N     . PHE B 1 121 ? 97.035  82.649  105.326 1.00 23.22 ? 121 PHE B N     1 
ATOM   3221 C  CA    . PHE B 1 121 ? 98.371  83.165  105.588 1.00 23.22 ? 121 PHE B CA    1 
ATOM   3222 C  C     . PHE B 1 121 ? 98.814  84.108  104.485 1.00 23.22 ? 121 PHE B C     1 
ATOM   3223 O  O     . PHE B 1 121 ? 99.304  85.200  104.759 1.00 23.22 ? 121 PHE B O     1 
ATOM   3224 C  CB    . PHE B 1 121 ? 99.343  81.992  105.735 1.00 23.22 ? 121 PHE B CB    1 
ATOM   3225 C  CG    . PHE B 1 121 ? 100.783 82.383  105.716 1.00 23.22 ? 121 PHE B CG    1 
ATOM   3226 C  CD1   . PHE B 1 121 ? 101.343 83.042  106.779 1.00 23.22 ? 121 PHE B CD1   1 
ATOM   3227 C  CD2   . PHE B 1 121 ? 101.579 82.086  104.627 1.00 23.22 ? 121 PHE B CD2   1 
ATOM   3228 C  CE1   . PHE B 1 121 ? 102.646 83.403  106.764 1.00 23.22 ? 121 PHE B CE1   1 
ATOM   3229 C  CE2   . PHE B 1 121 ? 102.889 82.452  104.610 1.00 23.22 ? 121 PHE B CE2   1 
ATOM   3230 C  CZ    . PHE B 1 121 ? 103.421 83.112  105.680 1.00 23.22 ? 121 PHE B CZ    1 
ATOM   3231 N  N     . LYS B 1 122 ? 98.687  83.688  103.228 1.00 21.63 ? 122 LYS B N     1 
ATOM   3232 C  CA    . LYS B 1 122 ? 99.040  84.557  102.111 1.00 21.63 ? 122 LYS B CA    1 
ATOM   3233 C  C     . LYS B 1 122 ? 98.098  85.750  101.989 1.00 21.63 ? 122 LYS B C     1 
ATOM   3234 O  O     . LYS B 1 122 ? 98.518  86.811  101.525 1.00 21.63 ? 122 LYS B O     1 
ATOM   3235 C  CB    . LYS B 1 122 ? 99.095  83.759  100.812 1.00 21.63 ? 122 LYS B CB    1 
ATOM   3236 C  CG    . LYS B 1 122 ? 100.335 82.905  100.632 1.00 21.63 ? 122 LYS B CG    1 
ATOM   3237 C  CD    . LYS B 1 122 ? 101.555 83.778  100.457 1.00 21.63 ? 122 LYS B CD    1 
ATOM   3238 C  CE    . LYS B 1 122 ? 102.812 82.970  100.222 1.00 21.63 ? 122 LYS B CE    1 
ATOM   3239 N  NZ    . LYS B 1 122 ? 104.003 83.825  100.002 1.00 21.63 ? 122 LYS B NZ    1 
ATOM   3240 N  N     . ASP B 1 123 ? 96.839  85.616  102.412 1.00 22.04 ? 123 ASP B N     1 
ATOM   3241 C  CA    . ASP B 1 123 ? 95.943  86.771  102.418 1.00 22.04 ? 123 ASP B CA    1 
ATOM   3242 C  C     . ASP B 1 123 ? 96.402  87.814  103.430 1.00 22.04 ? 123 ASP B C     1 
ATOM   3243 O  O     . ASP B 1 123 ? 96.515  89.006  103.106 1.00 22.04 ? 123 ASP B O     1 
ATOM   3244 C  CB    . ASP B 1 123 ? 94.511  86.339  102.763 1.00 22.04 ? 123 ASP B CB    1 
ATOM   3245 C  CG    . ASP B 1 123 ? 93.880  85.396  101.734 1.00 22.04 ? 123 ASP B CG    1 
ATOM   3246 O  OD1   . ASP B 1 123 ? 94.322  85.314  100.568 1.00 22.04 ? 123 ASP B OD1   1 
ATOM   3247 O  OD2   . ASP B 1 123 ? 92.903  84.728  102.110 1.00 22.04 ? 123 ASP B OD2   1 
ATOM   3248 N  N     . TYR B 1 124 ? 96.841  87.354  104.601 1.00 22.96 ? 124 TYR B N     1 
ATOM   3249 C  CA    . TYR B 1 124 ? 97.401  88.266  105.591 1.00 22.96 ? 124 TYR B CA    1 
ATOM   3250 C  C     . TYR B 1 124 ? 98.749  88.812  105.158 1.00 22.96 ? 124 TYR B C     1 
ATOM   3251 O  O     . TYR B 1 124 ? 99.033  89.992  105.376 1.00 22.96 ? 124 TYR B O     1 
ATOM   3252 C  CB    . TYR B 1 124 ? 97.568  87.568  106.941 1.00 22.96 ? 124 TYR B CB    1 
ATOM   3253 C  CG    . TYR B 1 124 ? 96.493  87.778  107.985 1.00 22.96 ? 124 TYR B CG    1 
ATOM   3254 C  CD1   . TYR B 1 124 ? 96.436  88.955  108.710 1.00 22.96 ? 124 TYR B CD1   1 
ATOM   3255 C  CD2   . TYR B 1 124 ? 95.624  86.762  108.333 1.00 22.96 ? 124 TYR B CD2   1 
ATOM   3256 C  CE1   . TYR B 1 124 ? 95.471  89.155  109.647 1.00 22.96 ? 124 TYR B CE1   1 
ATOM   3257 C  CE2   . TYR B 1 124 ? 94.682  86.933  109.313 1.00 22.96 ? 124 TYR B CE2   1 
ATOM   3258 C  CZ    . TYR B 1 124 ? 94.601  88.138  109.956 1.00 22.96 ? 124 TYR B CZ    1 
ATOM   3259 O  OH    . TYR B 1 124 ? 93.697  88.304  110.967 1.00 22.96 ? 124 TYR B OH    1 
ATOM   3260 N  N     . GLN B 1 125 ? 99.605  87.973  104.573 1.00 21.52 ? 125 GLN B N     1 
ATOM   3261 C  CA    . GLN B 1 125 ? 100.914 88.451  104.149 1.00 21.52 ? 125 GLN B CA    1 
ATOM   3262 C  C     . GLN B 1 125 ? 100.793 89.532  103.094 1.00 21.52 ? 125 GLN B C     1 
ATOM   3263 O  O     . GLN B 1 125 ? 101.538 90.509  103.122 1.00 21.52 ? 125 GLN B O     1 
ATOM   3264 C  CB    . GLN B 1 125 ? 101.783 87.314  103.614 1.00 21.52 ? 125 GLN B CB    1 
ATOM   3265 C  CG    . GLN B 1 125 ? 103.128 87.842  103.131 1.00 21.52 ? 125 GLN B CG    1 
ATOM   3266 C  CD    . GLN B 1 125 ? 104.120 86.783  102.739 1.00 21.52 ? 125 GLN B CD    1 
ATOM   3267 O  OE1   . GLN B 1 125 ? 104.186 86.383  101.589 1.00 21.52 ? 125 GLN B OE1   1 
ATOM   3268 N  NE2   . GLN B 1 125 ? 104.913 86.340  103.691 1.00 21.52 ? 125 GLN B NE2   1 
ATOM   3269 N  N     . GLU B 1 126 ? 99.927  89.335  102.105 1.00 21.01 ? 126 GLU B N     1 
ATOM   3270 C  CA    . GLU B 1 126 ? 99.757  90.360  101.091 1.00 21.01 ? 126 GLU B CA    1 
ATOM   3271 C  C     . GLU B 1 126 ? 99.209  91.635  101.707 1.00 21.01 ? 126 GLU B C     1 
ATOM   3272 O  O     . GLU B 1 126 ? 99.594  92.734  101.300 1.00 21.01 ? 126 GLU B O     1 
ATOM   3273 C  CB    . GLU B 1 126 ? 98.910  89.829  99.933  1.00 21.01 ? 126 GLU B CB    1 
ATOM   3274 C  CG    . GLU B 1 126 ? 97.443  89.649  100.166 1.00 21.01 ? 126 GLU B CG    1 
ATOM   3275 C  CD    . GLU B 1 126 ? 96.619  90.820  99.667  1.00 21.01 ? 126 GLU B CD    1 
ATOM   3276 O  OE1   . GLU B 1 126 ? 97.184  91.910  99.470  1.00 21.01 ? 126 GLU B OE1   1 
ATOM   3277 O  OE2   . GLU B 1 126 ? 95.404  90.638  99.470  1.00 21.01 ? 126 GLU B OE2   1 
ATOM   3278 N  N     . VAL B 1 127 ? 98.341  91.518  102.722 1.00 19.73 ? 127 VAL B N     1 
ATOM   3279 C  CA    . VAL B 1 127 ? 97.887  92.733  103.399 1.00 19.73 ? 127 VAL B CA    1 
ATOM   3280 C  C     . VAL B 1 127 ? 99.035  93.399  104.155 1.00 19.73 ? 127 VAL B C     1 
ATOM   3281 O  O     . VAL B 1 127 ? 99.141  94.630  104.183 1.00 19.73 ? 127 VAL B O     1 
ATOM   3282 C  CB    . VAL B 1 127 ? 96.713  92.438  104.350 1.00 19.73 ? 127 VAL B CB    1 
ATOM   3283 C  CG1   . VAL B 1 127 ? 96.326  93.675  105.087 1.00 19.73 ? 127 VAL B CG1   1 
ATOM   3284 C  CG2   . VAL B 1 127 ? 95.531  91.942  103.587 1.00 19.73 ? 127 VAL B CG2   1 
ATOM   3285 N  N     . ARG B 1 128 ? 99.948  92.604  104.704 1.00 19.19 ? 128 ARG B N     1 
ATOM   3286 C  CA    . ARG B 1 128 ? 101.109 93.139  105.406 1.00 19.19 ? 128 ARG B CA    1 
ATOM   3287 C  C     . ARG B 1 128 ? 102.039 93.864  104.448 1.00 19.19 ? 128 ARG B C     1 
ATOM   3288 O  O     . ARG B 1 128 ? 102.493 94.968  104.739 1.00 19.19 ? 128 ARG B O     1 
ATOM   3289 C  CB    . ARG B 1 128 ? 101.820 92.015  106.158 1.00 19.19 ? 128 ARG B CB    1 
ATOM   3290 C  CG    . ARG B 1 128 ? 102.928 92.452  107.111 1.00 19.19 ? 128 ARG B CG    1 
ATOM   3291 C  CD    . ARG B 1 128 ? 104.292 92.450  106.443 1.00 19.19 ? 128 ARG B CD    1 
ATOM   3292 N  NE    . ARG B 1 128 ? 104.672 91.096  106.070 1.00 19.19 ? 128 ARG B NE    1 
ATOM   3293 C  CZ    . ARG B 1 128 ? 105.699 90.786  105.296 1.00 19.19 ? 128 ARG B CZ    1 
ATOM   3294 N  NH1   . ARG B 1 128 ? 106.459 91.718  104.753 1.00 19.19 ? 128 ARG B NH1   1 
ATOM   3295 N  NH2   . ARG B 1 128 ? 105.971 89.509  105.065 1.00 19.19 ? 128 ARG B NH2   1 
ATOM   3296 N  N     . ILE B 1 129 ? 102.354 93.248  103.313 1.00 16.21 ? 129 ILE B N     1 
ATOM   3297 C  CA    . ILE B 1 129 ? 103.214 93.887  102.321 1.00 16.21 ? 129 ILE B CA    1 
ATOM   3298 C  C     . ILE B 1 129 ? 102.590 95.193  101.850 1.00 16.21 ? 129 ILE B C     1 
ATOM   3299 O  O     . ILE B 1 129 ? 103.251 96.228  101.798 1.00 16.21 ? 129 ILE B O     1 
ATOM   3300 C  CB    . ILE B 1 129 ? 103.493 92.921  101.157 1.00 16.21 ? 129 ILE B CB    1 
ATOM   3301 C  CG1   . ILE B 1 129 ? 104.339 91.752  101.646 1.00 16.21 ? 129 ILE B CG1   1 
ATOM   3302 C  CG2   . ILE B 1 129 ? 104.195 93.621  100.039 1.00 16.21 ? 129 ILE B CG2   1 
ATOM   3303 C  CD1   . ILE B 1 129 ? 104.422 90.634  100.714 1.00 16.21 ? 129 ILE B CD1   1 
ATOM   3304 N  N     . ARG B 1 130 ? 101.325 95.147  101.450 1.00 17.45 ? 130 ARG B N     1 
ATOM   3305 C  CA    . ARG B 1 130 ? 100.569 96.334  101.066 1.00 17.45 ? 130 ARG B CA    1 
ATOM   3306 C  C     . ARG B 1 130 ? 100.632 97.455  102.112 1.00 17.45 ? 130 ARG B C     1 
ATOM   3307 O  O     . ARG B 1 130 ? 100.932 98.614  101.787 1.00 17.45 ? 130 ARG B O     1 
ATOM   3308 C  CB    . ARG B 1 130 ? 99.136  95.863  100.859 1.00 17.45 ? 130 ARG B CB    1 
ATOM   3309 C  CG    . ARG B 1 130 ? 98.042  96.849  100.654 1.00 17.45 ? 130 ARG B CG    1 
ATOM   3310 C  CD    . ARG B 1 130 ? 96.738  96.050  100.623 1.00 17.45 ? 130 ARG B CD    1 
ATOM   3311 N  NE    . ARG B 1 130 ? 96.720  95.043  99.575  1.00 17.45 ? 130 ARG B NE    1 
ATOM   3312 C  CZ    . ARG B 1 130 ? 96.780  95.292  98.281  1.00 17.45 ? 130 ARG B CZ    1 
ATOM   3313 N  NH1   . ARG B 1 130 ? 96.496  96.483  97.796  1.00 17.45 ? 130 ARG B NH1   1 
ATOM   3314 N  NH2   . ARG B 1 130 ? 97.076  94.303  97.448  1.00 17.45 ? 130 ARG B NH2   1 
ATOM   3315 N  N     . THR B 1 131 ? 100.515 97.096  103.395 1.00 21.33 ? 131 THR B N     1 
ATOM   3316 C  CA    . THR B 1 131 ? 100.510 98.072  104.487 1.00 21.33 ? 131 THR B CA    1 
ATOM   3317 C  C     . THR B 1 131 ? 101.912 98.598  104.792 1.00 21.33 ? 131 THR B C     1 
ATOM   3318 O  O     . THR B 1 131 ? 102.089 99.789  105.061 1.00 21.33 ? 131 THR B O     1 
ATOM   3319 C  CB    . THR B 1 131 ? 99.916  97.414  105.738 1.00 21.33 ? 131 THR B CB    1 
ATOM   3320 O  OG1   . THR B 1 131 ? 98.624  96.884  105.440 1.00 21.33 ? 131 THR B OG1   1 
ATOM   3321 C  CG2   . THR B 1 131 ? 99.756  98.426  106.836 1.00 21.33 ? 131 THR B CG2   1 
ATOM   3322 N  N     . GLY B 1 132 ? 102.915 97.722  104.758 1.00 21.69 ? 132 GLY B N     1 
ATOM   3323 C  CA    . GLY B 1 132 ? 104.289 98.146  104.931 1.00 21.69 ? 132 GLY B CA    1 
ATOM   3324 C  C     . GLY B 1 132 ? 104.742 99.078  103.828 1.00 21.69 ? 132 GLY B C     1 
ATOM   3325 O  O     . GLY B 1 132 ? 105.491 100.020 104.073 1.00 21.69 ? 132 GLY B O     1 
ATOM   3326 N  N     . ASN B 1 133 ? 104.330 98.803  102.589 1.00 19.99 ? 133 ASN B N     1 
ATOM   3327 C  CA    . ASN B 1 133 ? 104.676 99.695  101.492 1.00 19.99 ? 133 ASN B CA    1 
ATOM   3328 C  C     . ASN B 1 133 ? 104.008 101.043 101.670 1.00 19.99 ? 133 ASN B C     1 
ATOM   3329 O  O     . ASN B 1 133 ? 104.596 102.083 101.341 1.00 19.99 ? 133 ASN B O     1 
ATOM   3330 C  CB    . ASN B 1 133 ? 104.242 99.102  100.160 1.00 19.99 ? 133 ASN B CB    1 
ATOM   3331 C  CG    . ASN B 1 133 ? 105.001 97.869  99.789  1.00 19.99 ? 133 ASN B CG    1 
ATOM   3332 O  OD1   . ASN B 1 133 ? 105.834 97.383  100.539 1.00 19.99 ? 133 ASN B OD1   1 
ATOM   3333 N  ND2   . ASN B 1 133 ? 104.712 97.349  98.617  1.00 19.99 ? 133 ASN B ND2   1 
ATOM   3334 N  N     . ARG B 1 134 ? 102.823 101.065 102.272 1.00 22.20 ? 134 ARG B N     1 
ATOM   3335 C  CA    . ARG B 1 134 ? 102.222 102.368 102.532 1.00 22.20 ? 134 ARG B CA    1 
ATOM   3336 C  C     . ARG B 1 134 ? 102.988 103.091 103.634 1.00 22.20 ? 134 ARG B C     1 
ATOM   3337 O  O     . ARG B 1 134 ? 103.119 104.317 103.598 1.00 22.20 ? 134 ARG B O     1 
ATOM   3338 C  CB    . ARG B 1 134 ? 100.730 102.237 102.822 1.00 22.20 ? 134 ARG B CB    1 
ATOM   3339 C  CG    . ARG B 1 134 ? 99.983  101.851 101.552 1.00 22.20 ? 134 ARG B CG    1 
ATOM   3340 C  CD    . ARG B 1 134 ? 98.494  102.016 101.616 1.00 22.20 ? 134 ARG B CD    1 
ATOM   3341 N  NE    . ARG B 1 134 ? 97.805  100.759 101.852 1.00 22.20 ? 134 ARG B NE    1 
ATOM   3342 C  CZ    . ARG B 1 134 ? 96.902  100.230 101.044 1.00 22.20 ? 134 ARG B CZ    1 
ATOM   3343 N  NH1   . ARG B 1 134 ? 96.778  100.623 99.794  1.00 22.20 ? 134 ARG B NH1   1 
ATOM   3344 N  NH2   . ARG B 1 134 ? 96.139  99.245  101.489 1.00 22.20 ? 134 ARG B NH2   1 
ATOM   3345 N  N     . LEU B 1 135 ? 103.469 102.351 104.636 1.00 26.54 ? 135 LEU B N     1 
ATOM   3346 C  CA    . LEU B 1 135 ? 104.314 102.942 105.675 1.00 26.54 ? 135 LEU B CA    1 
ATOM   3347 C  C     . LEU B 1 135 ? 105.617 103.473 105.105 1.00 26.54 ? 135 LEU B C     1 
ATOM   3348 O  O     . LEU B 1 135 ? 106.159 104.460 105.605 1.00 26.54 ? 135 LEU B O     1 
ATOM   3349 C  CB    . LEU B 1 135 ? 104.615 101.912 106.754 1.00 26.54 ? 135 LEU B CB    1 
ATOM   3350 C  CG    . LEU B 1 135 ? 103.917 102.008 108.095 1.00 26.54 ? 135 LEU B CG    1 
ATOM   3351 C  CD1   . LEU B 1 135 ? 102.506 102.364 107.914 1.00 26.54 ? 135 LEU B CD1   1 
ATOM   3352 C  CD2   . LEU B 1 135 ? 103.987 100.628 108.685 1.00 26.54 ? 135 LEU B CD2   1 
ATOM   3353 N  N     . TYR B 1 136 ? 106.129 102.842 104.054 1.00 27.77 ? 136 TYR B N     1 
ATOM   3354 C  CA    . TYR B 1 136 ? 107.336 103.353 103.421 1.00 27.77 ? 136 TYR B CA    1 
ATOM   3355 C  C     . TYR B 1 136 ? 107.047 104.655 102.703 1.00 27.77 ? 136 TYR B C     1 
ATOM   3356 O  O     . TYR B 1 136 ? 107.886 105.558 102.670 1.00 27.77 ? 136 TYR B O     1 
ATOM   3357 C  CB    . TYR B 1 136 ? 107.893 102.343 102.421 1.00 27.77 ? 136 TYR B CB    1 
ATOM   3358 C  CG    . TYR B 1 136 ? 109.150 102.847 101.767 1.00 27.77 ? 136 TYR B CG    1 
ATOM   3359 C  CD1   . TYR B 1 136 ? 110.350 102.872 102.447 1.00 27.77 ? 136 TYR B CD1   1 
ATOM   3360 C  CD2   . TYR B 1 136 ? 109.110 103.409 100.497 1.00 27.77 ? 136 TYR B CD2   1 
ATOM   3361 C  CE1   . TYR B 1 136 ? 111.487 103.369 101.856 1.00 27.77 ? 136 TYR B CE1   1 
ATOM   3362 C  CE2   . TYR B 1 136 ? 110.239 103.910 99.905  1.00 27.77 ? 136 TYR B CE2   1 
ATOM   3363 C  CZ    . TYR B 1 136 ? 111.425 103.888 100.586 1.00 27.77 ? 136 TYR B CZ    1 
ATOM   3364 O  OH    . TYR B 1 136 ? 112.562 104.394 100.000 1.00 27.77 ? 136 TYR B OH    1 
ATOM   3365 N  N     . SER B 1 137 ? 105.871 104.763 102.112 1.00 29.31 ? 137 SER B N     1 
ATOM   3366 C  CA    . SER B 1 137 ? 105.536 105.950 101.341 1.00 29.31 ? 137 SER B CA    1 
ATOM   3367 C  C     . SER B 1 137 ? 105.084 107.109 102.228 1.00 29.31 ? 137 SER B C     1 
ATOM   3368 O  O     . SER B 1 137 ? 105.350 108.269 101.909 1.00 29.31 ? 137 SER B O     1 
ATOM   3369 C  CB    . SER B 1 137 ? 104.495 105.590 100.301 1.00 29.31 ? 137 SER B CB    1 
ATOM   3370 O  OG    . SER B 1 137 ? 104.972 104.516 99.508  1.00 29.31 ? 137 SER B OG    1 
ATOM   3371 N  N     . ASP B 1 138 ? 104.400 106.824 103.332 1.00 35.33 ? 138 ASP B N     1 
ATOM   3372 C  CA    . ASP B 1 138 ? 103.959 107.847 104.271 1.00 35.33 ? 138 ASP B CA    1 
ATOM   3373 C  C     . ASP B 1 138 ? 103.842 107.223 105.647 1.00 35.33 ? 138 ASP B C     1 
ATOM   3374 O  O     . ASP B 1 138 ? 103.516 106.046 105.780 1.00 35.33 ? 138 ASP B O     1 
ATOM   3375 C  CB    . ASP B 1 138 ? 102.591 108.419 103.869 1.00 35.33 ? 138 ASP B CB    1 
ATOM   3376 C  CG    . ASP B 1 138 ? 102.426 109.889 104.213 1.00 35.33 ? 138 ASP B CG    1 
ATOM   3377 O  OD1   . ASP B 1 138 ? 102.866 110.303 105.304 1.00 35.33 ? 138 ASP B OD1   1 
ATOM   3378 O  OD2   . ASP B 1 138 ? 101.812 110.627 103.409 1.00 35.33 ? 138 ASP B OD2   1 
ATOM   3379 N  N     . ARG B 1 139 ? 104.051 108.032 106.676 1.00 37.21 ? 139 ARG B N     1 
ATOM   3380 C  CA    . ARG B 1 139 ? 104.017 107.556 108.051 1.00 37.21 ? 139 ARG B CA    1 
ATOM   3381 C  C     . ARG B 1 139 ? 102.814 108.137 108.773 1.00 37.21 ? 139 ARG B C     1 
ATOM   3382 O  O     . ARG B 1 139 ? 102.569 109.344 108.710 1.00 37.21 ? 139 ARG B O     1 
ATOM   3383 C  CB    . ARG B 1 139 ? 105.313 107.884 108.784 1.00 37.21 ? 139 ARG B CB    1 
ATOM   3384 C  CG    . ARG B 1 139 ? 105.716 106.768 109.685 1.00 37.21 ? 139 ARG B CG    1 
ATOM   3385 C  CD    . ARG B 1 139 ? 106.234 105.604 108.871 1.00 37.21 ? 139 ARG B CD    1 
ATOM   3386 N  NE    . ARG B 1 139 ? 106.588 104.485 109.734 1.00 37.21 ? 139 ARG B NE    1 
ATOM   3387 C  CZ    . ARG B 1 139 ? 107.499 103.563 109.461 1.00 37.21 ? 139 ARG B CZ    1 
ATOM   3388 N  NH1   . ARG B 1 139 ? 108.163 103.560 108.320 1.00 37.21 ? 139 ARG B NH1   1 
ATOM   3389 N  NH2   . ARG B 1 139 ? 107.725 102.601 110.347 1.00 37.21 ? 139 ARG B NH2   1 
ATOM   3390 N  N     . THR B 1 140 ? 102.037 107.255 109.398 1.00 40.31 ? 140 THR B N     1 
ATOM   3391 C  CA    . THR B 1 140 ? 100.827 107.615 110.121 1.00 40.31 ? 140 THR B CA    1 
ATOM   3392 C  C     . THR B 1 140 ? 100.689 106.687 111.316 1.00 40.31 ? 140 THR B C     1 
ATOM   3393 O  O     . THR B 1 140 ? 101.112 105.528 111.266 1.00 40.31 ? 140 THR B O     1 
ATOM   3394 C  CB    . THR B 1 140 ? 99.572  107.460 109.255 1.00 40.31 ? 140 THR B CB    1 
ATOM   3395 O  OG1   . THR B 1 140 ? 99.542  106.139 108.709 1.00 40.31 ? 140 THR B OG1   1 
ATOM   3396 C  CG2   . THR B 1 140 ? 99.559  108.448 108.106 1.00 40.31 ? 140 THR B CG2   1 
ATOM   3397 N  N     . ASP B 1 141 ? 100.109 107.200 112.400 1.00 40.65 ? 141 ASP B N     1 
ATOM   3398 C  CA    . ASP B 1 141 ? 99.903  106.343 113.562 1.00 40.65 ? 141 ASP B CA    1 
ATOM   3399 C  C     . ASP B 1 141 ? 98.870  105.265 113.278 1.00 40.65 ? 141 ASP B C     1 
ATOM   3400 O  O     . ASP B 1 141 ? 99.013  104.123 113.737 1.00 40.65 ? 141 ASP B O     1 
ATOM   3401 C  CB    . ASP B 1 141 ? 99.452  107.170 114.770 1.00 40.65 ? 141 ASP B CB    1 
ATOM   3402 C  CG    . ASP B 1 141 ? 100.499 108.152 115.240 1.00 40.65 ? 141 ASP B CG    1 
ATOM   3403 O  OD1   . ASP B 1 141 ? 101.620 108.140 114.701 1.00 40.65 ? 141 ASP B OD1   1 
ATOM   3404 O  OD2   . ASP B 1 141 ? 100.200 108.938 116.164 1.00 40.65 ? 141 ASP B OD2   1 
ATOM   3405 N  N     . ALA B 1 142 ? 97.856  105.607 112.482 1.00 37.07 ? 142 ALA B N     1 
ATOM   3406 C  CA    . ALA B 1 142 ? 96.787  104.678 112.141 1.00 37.07 ? 142 ALA B CA    1 
ATOM   3407 C  C     . ALA B 1 142 ? 97.319  103.427 111.465 1.00 37.07 ? 142 ALA B C     1 
ATOM   3408 O  O     . ALA B 1 142 ? 97.037  102.300 111.891 1.00 37.07 ? 142 ALA B O     1 
ATOM   3409 C  CB    . ALA B 1 142 ? 95.785  105.379 111.233 1.00 37.07 ? 142 ALA B CB    1 
ATOM   3410 N  N     . MET B 1 143 ? 98.172  103.607 110.468 1.00 34.75 ? 143 MET B N     1 
ATOM   3411 C  CA    . MET B 1 143 ? 98.700  102.457 109.764 1.00 34.75 ? 143 MET B CA    1 
ATOM   3412 C  C     . MET B 1 143 ? 99.790  101.746 110.539 1.00 34.75 ? 143 MET B C     1 
ATOM   3413 O  O     . MET B 1 143 ? 100.020 100.576 110.283 1.00 34.75 ? 143 MET B O     1 
ATOM   3414 C  CB    . MET B 1 143 ? 99.186  102.865 108.381 1.00 34.75 ? 143 MET B CB    1 
ATOM   3415 C  CG    . MET B 1 143 ? 98.080  103.395 107.495 1.00 34.75 ? 143 MET B CG    1 
ATOM   3416 S  SD    . MET B 1 143 ? 96.810  102.179 107.111 1.00 34.75 ? 143 MET B SD    1 
ATOM   3417 C  CE    . MET B 1 143 ? 97.595  101.272 105.793 1.00 34.75 ? 143 MET B CE    1 
ATOM   3418 N  N     . GLU B 1 144 ? 100.498 102.414 111.453 1.00 36.06 ? 144 GLU B N     1 
ATOM   3419 C  CA    . GLU B 1 144 ? 101.497 101.697 112.243 1.00 36.06 ? 144 GLU B CA    1 
ATOM   3420 C  C     . GLU B 1 144 ? 100.826 100.770 113.245 1.00 36.06 ? 144 GLU B C     1 
ATOM   3421 O  O     . GLU B 1 144 ? 101.247 99.615  113.429 1.00 36.06 ? 144 GLU B O     1 
ATOM   3422 C  CB    . GLU B 1 144 ? 102.421 102.684 112.944 1.00 36.06 ? 144 GLU B CB    1 
ATOM   3423 C  CG    . GLU B 1 144 ? 103.467 103.274 112.027 1.00 36.06 ? 144 GLU B CG    1 
ATOM   3424 C  CD    . GLU B 1 144 ? 104.622 103.908 112.773 1.00 36.06 ? 144 GLU B CD    1 
ATOM   3425 O  OE1   . GLU B 1 144 ? 104.410 104.413 113.892 1.00 36.06 ? 144 GLU B OE1   1 
ATOM   3426 O  OE2   . GLU B 1 144 ? 105.756 103.879 112.254 1.00 36.06 ? 144 GLU B OE2   1 
ATOM   3427 N  N     . GLU B 1 145 ? 99.728  101.230 113.839 1.00 36.87 ? 145 GLU B N     1 
ATOM   3428 C  CA    . GLU B 1 145 ? 98.968  100.379 114.742 1.00 36.87 ? 145 GLU B CA    1 
ATOM   3429 C  C     . GLU B 1 145 ? 98.358  99.226  113.954 1.00 36.87 ? 145 GLU B C     1 
ATOM   3430 O  O     . GLU B 1 145 ? 98.405  98.057  114.379 1.00 36.87 ? 145 GLU B O     1 
ATOM   3431 C  CB    . GLU B 1 145 ? 97.899  101.243 115.420 1.00 36.87 ? 145 GLU B CB    1 
ATOM   3432 C  CG    . GLU B 1 145 ? 96.924  100.590 116.394 1.00 36.87 ? 145 GLU B CG    1 
ATOM   3433 C  CD    . GLU B 1 145 ? 97.591  99.898  117.568 1.00 36.87 ? 145 GLU B CD    1 
ATOM   3434 O  OE1   . GLU B 1 145 ? 98.699  100.320 117.963 1.00 36.87 ? 145 GLU B OE1   1 
ATOM   3435 O  OE2   . GLU B 1 145 ? 96.985  98.951  118.117 1.00 36.87 ? 145 GLU B OE2   1 
ATOM   3436 N  N     . PHE B 1 146 ? 97.864  99.533  112.749 1.00 30.73 ? 146 PHE B N     1 
ATOM   3437 C  CA    . PHE B 1 146 ? 97.338  98.501  111.865 1.00 30.73 ? 146 PHE B CA    1 
ATOM   3438 C  C     . PHE B 1 146 ? 98.415  97.519  111.429 1.00 30.73 ? 146 PHE B C     1 
ATOM   3439 O  O     . PHE B 1 146 ? 98.165  96.314  111.361 1.00 30.73 ? 146 PHE B O     1 
ATOM   3440 C  CB    . PHE B 1 146 ? 96.682  99.143  110.647 1.00 30.73 ? 146 PHE B CB    1 
ATOM   3441 C  CG    . PHE B 1 146 ? 95.925  98.170  109.798 1.00 30.73 ? 146 PHE B CG    1 
ATOM   3442 C  CD1   . PHE B 1 146 ? 94.908  97.416  110.335 1.00 30.73 ? 146 PHE B CD1   1 
ATOM   3443 C  CD2   . PHE B 1 146 ? 96.221  98.023  108.466 1.00 30.73 ? 146 PHE B CD2   1 
ATOM   3444 C  CE1   . PHE B 1 146 ? 94.229  96.521  109.564 1.00 30.73 ? 146 PHE B CE1   1 
ATOM   3445 C  CE2   . PHE B 1 146 ? 95.530  97.140  107.694 1.00 30.73 ? 146 PHE B CE2   1 
ATOM   3446 C  CZ    . PHE B 1 146 ? 94.539  96.385  108.243 1.00 30.73 ? 146 PHE B CZ    1 
ATOM   3447 N  N     . PHE B 1 147 ? 99.590  98.024  111.057 1.00 30.32 ? 147 PHE B N     1 
ATOM   3448 C  CA    . PHE B 1 147 ? 100.691 97.178  110.624 1.00 30.32 ? 147 PHE B CA    1 
ATOM   3449 C  C     . PHE B 1 147 ? 101.045 96.171  111.699 1.00 30.32 ? 147 PHE B C     1 
ATOM   3450 O  O     . PHE B 1 147 ? 101.321 95.006  111.404 1.00 30.32 ? 147 PHE B O     1 
ATOM   3451 C  CB    . PHE B 1 147 ? 101.891 98.054  110.260 1.00 30.32 ? 147 PHE B CB    1 
ATOM   3452 C  CG    . PHE B 1 147 ? 103.077 97.294  109.725 1.00 30.32 ? 147 PHE B CG    1 
ATOM   3453 C  CD1   . PHE B 1 147 ? 103.007 96.624  108.520 1.00 30.32 ? 147 PHE B CD1   1 
ATOM   3454 C  CD2   . PHE B 1 147 ? 104.276 97.299  110.398 1.00 30.32 ? 147 PHE B CD2   1 
ATOM   3455 C  CE1   . PHE B 1 147 ? 104.092 95.948  108.024 1.00 30.32 ? 147 PHE B CE1   1 
ATOM   3456 C  CE2   . PHE B 1 147 ? 105.363 96.626  109.898 1.00 30.32 ? 147 PHE B CE2   1 
ATOM   3457 C  CZ    . PHE B 1 147 ? 105.267 95.948  108.710 1.00 30.32 ? 147 PHE B CZ    1 
ATOM   3458 N  N     . LYS B 1 148 ? 101.009 96.604  112.957 1.00 33.70 ? 148 LYS B N     1 
ATOM   3459 C  CA    . LYS B 1 148 ? 101.272 95.700  114.071 1.00 33.70 ? 148 LYS B CA    1 
ATOM   3460 C  C     . LYS B 1 148 ? 100.189 94.625  114.190 1.00 33.70 ? 148 LYS B C     1 
ATOM   3461 O  O     . LYS B 1 148 ? 100.499 93.442  114.379 1.00 33.70 ? 148 LYS B O     1 
ATOM   3462 C  CB    . LYS B 1 148 ? 101.417 96.520  115.348 1.00 33.70 ? 148 LYS B CB    1 
ATOM   3463 C  CG    . LYS B 1 148 ? 102.150 95.825  116.468 1.00 33.70 ? 148 LYS B CG    1 
ATOM   3464 C  CD    . LYS B 1 148 ? 102.387 96.788  117.615 1.00 33.70 ? 148 LYS B CD    1 
ATOM   3465 C  CE    . LYS B 1 148 ? 103.406 97.845  117.223 1.00 33.70 ? 148 LYS B CE    1 
ATOM   3466 N  NZ    . LYS B 1 148 ? 104.794 97.294  117.316 1.00 33.70 ? 148 LYS B NZ    1 
ATOM   3467 N  N     . ILE B 1 149 ? 98.921  95.006  114.016 1.00 31.37 ? 149 ILE B N     1 
ATOM   3468 C  CA    . ILE B 1 149 ? 97.828  94.023  114.034 1.00 31.37 ? 149 ILE B CA    1 
ATOM   3469 C  C     . ILE B 1 149 ? 97.948  93.013  112.888 1.00 31.37 ? 149 ILE B C     1 
ATOM   3470 O  O     . ILE B 1 149 ? 97.772  91.797  113.083 1.00 31.37 ? 149 ILE B O     1 
ATOM   3471 C  CB    . ILE B 1 149 ? 96.471  94.751  113.977 1.00 31.37 ? 149 ILE B CB    1 
ATOM   3472 C  CG1   . ILE B 1 149 ? 96.246  95.593  115.220 1.00 31.37 ? 149 ILE B CG1   1 
ATOM   3473 C  CG2   . ILE B 1 149 ? 95.339  93.780  113.762 1.00 31.37 ? 149 ILE B CG2   1 
ATOM   3474 C  CD1   . ILE B 1 149 ? 95.210  96.676  115.021 1.00 31.37 ? 149 ILE B CD1   1 
ATOM   3475 N  N     . VAL B 1 150 ? 98.267  93.492  111.683 1.00 30.08 ? 150 VAL B N     1 
ATOM   3476 C  CA    . VAL B 1 150 ? 98.413  92.611  110.525 1.00 30.08 ? 150 VAL B CA    1 
ATOM   3477 C  C     . VAL B 1 150 ? 99.600  91.670  110.702 1.00 30.08 ? 150 VAL B C     1 
ATOM   3478 O  O     . VAL B 1 150 ? 99.516  90.480  110.364 1.00 30.08 ? 150 VAL B O     1 
ATOM   3479 C  CB    . VAL B 1 150 ? 98.555  93.428  109.232 1.00 30.08 ? 150 VAL B CB    1 
ATOM   3480 C  CG1   . VAL B 1 150 ? 98.721  92.497  108.092 1.00 30.08 ? 150 VAL B CG1   1 
ATOM   3481 C  CG2   . VAL B 1 150 ? 97.366  94.317  108.993 1.00 30.08 ? 150 VAL B CG2   1 
ATOM   3482 N  N     . LYS B 1 151 ? 100.732 92.189  111.188 1.00 31.01 ? 151 LYS B N     1 
ATOM   3483 C  CA    . LYS B 1 151 ? 101.879 91.337  111.474 1.00 31.01 ? 151 LYS B CA    1 
ATOM   3484 C  C     . LYS B 1 151 ? 101.520 90.249  112.472 1.00 31.01 ? 151 LYS B C     1 
ATOM   3485 O  O     . LYS B 1 151 ? 101.945 89.100  112.319 1.00 31.01 ? 151 LYS B O     1 
ATOM   3486 C  CB    . LYS B 1 151 ? 103.052 92.162  111.986 1.00 31.01 ? 151 LYS B CB    1 
ATOM   3487 C  CG    . LYS B 1 151 ? 103.991 92.641  110.918 1.00 31.01 ? 151 LYS B CG    1 
ATOM   3488 C  CD    . LYS B 1 151 ? 105.043 93.574  111.469 1.00 31.01 ? 151 LYS B CD    1 
ATOM   3489 C  CE    . LYS B 1 151 ? 105.805 92.942  112.637 1.00 31.01 ? 151 LYS B CE    1 
ATOM   3490 N  NZ    . LYS B 1 151 ? 106.726 91.813  112.281 1.00 31.01 ? 151 LYS B NZ    1 
ATOM   3491 N  N     . LYS B 1 152 ? 100.749 90.588  113.504 1.00 32.72 ? 152 LYS B N     1 
ATOM   3492 C  CA    . LYS B 1 152 ? 100.330 89.565  114.455 1.00 32.72 ? 152 LYS B CA    1 
ATOM   3493 C  C     . LYS B 1 152 ? 99.531  88.465  113.770 1.00 32.72 ? 152 LYS B C     1 
ATOM   3494 O  O     . LYS B 1 152 ? 99.745  87.278  114.034 1.00 32.72 ? 152 LYS B O     1 
ATOM   3495 C  CB    . LYS B 1 152 ? 99.494  90.187  115.565 1.00 32.72 ? 152 LYS B CB    1 
ATOM   3496 C  CG    . LYS B 1 152 ? 99.078  89.200  116.639 1.00 32.72 ? 152 LYS B CG    1 
ATOM   3497 C  CD    . LYS B 1 152 ? 98.265  89.885  117.719 1.00 32.72 ? 152 LYS B CD    1 
ATOM   3498 C  CE    . LYS B 1 152 ? 97.792  88.911  118.777 1.00 32.72 ? 152 LYS B CE    1 
ATOM   3499 N  NZ    . LYS B 1 152 ? 97.017  89.588  119.869 1.00 32.72 ? 152 LYS B NZ    1 
ATOM   3500 N  N     . GLY B 1 153 ? 98.599  88.842  112.892 1.00 31.68 ? 153 GLY B N     1 
ATOM   3501 C  CA    . GLY B 1 153 ? 97.827  87.832  112.176 1.00 31.68 ? 153 GLY B CA    1 
ATOM   3502 C  C     . GLY B 1 153 ? 98.682  86.936  111.298 1.00 31.68 ? 153 GLY B C     1 
ATOM   3503 O  O     . GLY B 1 153 ? 98.517  85.714  111.288 1.00 31.68 ? 153 GLY B O     1 
ATOM   3504 N  N     . GLU B 1 154 ? 99.609  87.535  110.548 1.00 29.08 ? 154 GLU B N     1 
ATOM   3505 C  CA    . GLU B 1 154 ? 100.532 86.762  109.719 1.00 29.08 ? 154 GLU B CA    1 
ATOM   3506 C  C     . GLU B 1 154 ? 101.376 85.806  110.554 1.00 29.08 ? 154 GLU B C     1 
ATOM   3507 O  O     . GLU B 1 154 ? 101.566 84.649  110.177 1.00 29.08 ? 154 GLU B O     1 
ATOM   3508 C  CB    . GLU B 1 154 ? 101.412 87.711  108.904 1.00 29.08 ? 154 GLU B CB    1 
ATOM   3509 C  CG    . GLU B 1 154 ? 102.373 87.036  107.941 1.00 29.08 ? 154 GLU B CG    1 
ATOM   3510 C  CD    . GLU B 1 154 ? 103.300 88.025  107.249 1.00 29.08 ? 154 GLU B CD    1 
ATOM   3511 O  OE1   . GLU B 1 154 ? 103.209 89.230  107.543 1.00 29.08 ? 154 GLU B OE1   1 
ATOM   3512 O  OE2   . GLU B 1 154 ? 104.144 87.605  106.432 1.00 29.08 ? 154 GLU B OE2   1 
ATOM   3513 N  N     . HIS B 1 155 ? 101.860 86.264  111.705 1.00 34.12 ? 155 HIS B N     1 
ATOM   3514 C  CA    . HIS B 1 155 ? 102.669 85.435  112.597 1.00 34.12 ? 155 HIS B CA    1 
ATOM   3515 C  C     . HIS B 1 155 ? 101.875 84.248  113.139 1.00 34.12 ? 155 HIS B C     1 
ATOM   3516 O  O     . HIS B 1 155 ? 102.342 83.101  113.114 1.00 34.12 ? 155 HIS B O     1 
ATOM   3517 C  CB    . HIS B 1 155 ? 103.176 86.311  113.740 1.00 34.12 ? 155 HIS B CB    1 
ATOM   3518 C  CG    . HIS B 1 155 ? 104.123 85.628  114.671 1.00 34.12 ? 155 HIS B CG    1 
ATOM   3519 N  ND1   . HIS B 1 155 ? 105.376 85.207  114.289 1.00 34.12 ? 155 HIS B ND1   1 
ATOM   3520 C  CD2   . HIS B 1 155 ? 103.985 85.271  115.970 1.00 34.12 ? 155 HIS B CD2   1 
ATOM   3521 C  CE1   . HIS B 1 155 ? 105.976 84.634  115.317 1.00 34.12 ? 155 HIS B CE1   1 
ATOM   3522 N  NE2   . HIS B 1 155 ? 105.153 84.660  116.348 1.00 34.12 ? 155 HIS B NE2   1 
ATOM   3523 N  N     . GLU B 1 156 ? 100.679 84.514  113.663 1.00 35.43 ? 156 GLU B N     1 
ATOM   3524 C  CA    . GLU B 1 156 ? 99.822  83.442  114.156 1.00 35.43 ? 156 GLU B CA    1 
ATOM   3525 C  C     . GLU B 1 156 ? 99.470  82.441  113.062 1.00 35.43 ? 156 GLU B C     1 
ATOM   3526 O  O     . GLU B 1 156 ? 99.425  81.234  113.312 1.00 35.43 ? 156 GLU B O     1 
ATOM   3527 C  CB    . GLU B 1 156 ? 98.565  84.041  114.783 1.00 35.43 ? 156 GLU B CB    1 
ATOM   3528 C  CG    . GLU B 1 156 ? 98.844  84.774  116.086 1.00 35.43 ? 156 GLU B CG    1 
ATOM   3529 C  CD    . GLU B 1 156 ? 99.535  83.906  117.135 1.00 35.43 ? 156 GLU B CD    1 
ATOM   3530 O  OE1   . GLU B 1 156 ? 99.180  82.715  117.265 1.00 35.43 ? 156 GLU B OE1   1 
ATOM   3531 O  OE2   . GLU B 1 156 ? 100.446 84.413  117.824 1.00 35.43 ? 156 GLU B OE2   1 
ATOM   3532 N  N     . LEU B 1 157 ? 99.244  82.902  111.831 1.00 30.65 ? 157 LEU B N     1 
ATOM   3533 C  CA    . LEU B 1 157 ? 98.959  81.933  110.773 1.00 30.65 ? 157 LEU B CA    1 
ATOM   3534 C  C     . LEU B 1 157 ? 100.198 81.195  110.303 1.00 30.65 ? 157 LEU B C     1 
ATOM   3535 O  O     . LEU B 1 157 ? 100.086 80.069  109.807 1.00 30.65 ? 157 LEU B O     1 
ATOM   3536 C  CB    . LEU B 1 157 ? 98.246  82.605  109.614 1.00 30.65 ? 157 LEU B CB    1 
ATOM   3537 C  CG    . LEU B 1 157 ? 96.775  82.643  110.005 1.00 30.65 ? 157 LEU B CG    1 
ATOM   3538 C  CD1   . LEU B 1 157 ? 96.146  83.848  109.460 1.00 30.65 ? 157 LEU B CD1   1 
ATOM   3539 C  CD2   . LEU B 1 157 ? 96.089  81.415  109.449 1.00 30.65 ? 157 LEU B CD2   1 
ATOM   3540 N  N     . LYS B 1 158 ? 101.377 81.794  110.441 1.00 31.08 ? 158 LYS B N     1 
ATOM   3541 C  CA    . LYS B 1 158 ? 102.590 81.044  110.164 1.00 31.08 ? 158 LYS B CA    1 
ATOM   3542 C  C     . LYS B 1 158 ? 102.714 79.906  111.163 1.00 31.08 ? 158 LYS B C     1 
ATOM   3543 O  O     . LYS B 1 158 ? 103.081 78.786  110.800 1.00 31.08 ? 158 LYS B O     1 
ATOM   3544 C  CB    . LYS B 1 158 ? 103.816 81.949  110.206 1.00 31.08 ? 158 LYS B CB    1 
ATOM   3545 C  CG    . LYS B 1 158 ? 105.039 81.304  109.580 1.00 31.08 ? 158 LYS B CG    1 
ATOM   3546 C  CD    . LYS B 1 158 ? 106.244 82.225  109.524 1.00 31.08 ? 158 LYS B CD    1 
ATOM   3547 C  CE    . LYS B 1 158 ? 106.739 82.582  110.912 1.00 31.08 ? 158 LYS B CE    1 
ATOM   3548 N  NZ    . LYS B 1 158 ? 107.999 83.371  110.876 1.00 31.08 ? 158 LYS B NZ    1 
ATOM   3549 N  N     . LYS B 1 159 ? 102.416 80.186  112.434 1.00 34.37 ? 159 LYS B N     1 
ATOM   3550 C  CA    . LYS B 1 159 ? 102.411 79.132  113.446 1.00 34.37 ? 159 LYS B CA    1 
ATOM   3551 C  C     . LYS B 1 159 ? 101.336 78.092  113.150 1.00 34.37 ? 159 LYS B C     1 
ATOM   3552 O  O     . LYS B 1 159 ? 101.547 76.903  113.378 1.00 34.37 ? 159 LYS B O     1 
ATOM   3553 C  CB    . LYS B 1 159 ? 102.218 79.739  114.836 1.00 34.37 ? 159 LYS B CB    1 
ATOM   3554 C  CG    . LYS B 1 159 ? 103.369 80.623  115.289 1.00 34.37 ? 159 LYS B CG    1 
ATOM   3555 C  CD    . LYS B 1 159 ? 102.979 81.572  116.434 1.00 34.37 ? 159 LYS B CD    1 
ATOM   3556 C  CE    . LYS B 1 159 ? 102.666 80.864  117.737 1.00 34.37 ? 159 LYS B CE    1 
ATOM   3557 N  NZ    . LYS B 1 159 ? 103.906 80.483  118.488 1.00 34.37 ? 159 LYS B NZ    1 
ATOM   3558 N  N     . ALA B 1 160 ? 100.201 78.512  112.594 1.00 33.78 ? 160 ALA B N     1 
ATOM   3559 C  CA    . ALA B 1 160 ? 99.152  77.566  112.213 1.00 33.78 ? 160 ALA B CA    1 
ATOM   3560 C  C     . ALA B 1 160 ? 99.597  76.659  111.066 1.00 33.78 ? 160 ALA B C     1 
ATOM   3561 O  O     . ALA B 1 160 ? 99.356  75.448  111.096 1.00 33.78 ? 160 ALA B O     1 
ATOM   3562 C  CB    . ALA B 1 160 ? 97.883  78.329  111.840 1.00 33.78 ? 160 ALA B CB    1 
ATOM   3563 N  N     . VAL B 1 161 ? 100.254 77.225  110.051 1.00 33.50 ? 161 VAL B N     1 
ATOM   3564 C  CA    . VAL B 1 161 ? 100.792 76.438  108.939 1.00 33.50 ? 161 VAL B CA    1 
ATOM   3565 C  C     . VAL B 1 161 ? 101.851 75.471  109.443 1.00 33.50 ? 161 VAL B C     1 
ATOM   3566 O  O     . VAL B 1 161 ? 101.858 74.283  109.101 1.00 33.50 ? 161 VAL B O     1 
ATOM   3567 C  CB    . VAL B 1 161 ? 101.358 77.368  107.851 1.00 33.50 ? 161 VAL B CB    1 
ATOM   3568 C  CG1   . VAL B 1 161 ? 102.199 76.605  106.873 1.00 33.50 ? 161 VAL B CG1   1 
ATOM   3569 C  CG2   . VAL B 1 161 ? 100.241 78.040  107.121 1.00 33.50 ? 161 VAL B CG2   1 
ATOM   3570 N  N     . ASP B 1 162 ? 102.791 75.993  110.225 1.00 36.61 ? 162 ASP B N     1 
ATOM   3571 C  CA    . ASP B 1 162 ? 103.849 75.200  110.830 1.00 36.61 ? 162 ASP B CA    1 
ATOM   3572 C  C     . ASP B 1 162 ? 103.280 74.034  111.624 1.00 36.61 ? 162 ASP B C     1 
ATOM   3573 O  O     . ASP B 1 162 ? 103.764 72.903  111.525 1.00 36.61 ? 162 ASP B O     1 
ATOM   3574 C  CB    . ASP B 1 162 ? 104.699 76.131  111.691 1.00 36.61 ? 162 ASP B CB    1 
ATOM   3575 C  CG    . ASP B 1 162 ? 105.778 75.421  112.457 1.00 36.61 ? 162 ASP B CG    1 
ATOM   3576 O  OD1   . ASP B 1 162 ? 106.302 74.395  111.979 1.00 36.61 ? 162 ASP B OD1   1 
ATOM   3577 O  OD2   . ASP B 1 162 ? 106.134 75.927  113.541 1.00 36.61 ? 162 ASP B OD2   1 
ATOM   3578 N  N     . LYS B 1 163 ? 102.246 74.295  112.420 1.00 38.30 ? 163 LYS B N     1 
ATOM   3579 C  CA    . LYS B 1 163 ? 101.584 73.247  113.194 1.00 38.30 ? 163 LYS B CA    1 
ATOM   3580 C  C     . LYS B 1 163 ? 100.887 72.221  112.304 1.00 38.30 ? 163 LYS B C     1 
ATOM   3581 O  O     . LYS B 1 163 ? 100.968 71.021  112.563 1.00 38.30 ? 163 LYS B O     1 
ATOM   3582 C  CB    . LYS B 1 163 ? 100.616 73.896  114.181 1.00 38.30 ? 163 LYS B CB    1 
ATOM   3583 C  CG    . LYS B 1 163 ? 100.050 72.978  115.237 1.00 38.30 ? 163 LYS B CG    1 
ATOM   3584 C  CD    . LYS B 1 163 ? 99.099  73.758  116.121 1.00 38.30 ? 163 LYS B CD    1 
ATOM   3585 C  CE    . LYS B 1 163 ? 98.484  72.895  117.193 1.00 38.30 ? 163 LYS B CE    1 
ATOM   3586 N  NZ    . LYS B 1 163 ? 97.427  73.635  117.933 1.00 38.30 ? 163 LYS B NZ    1 
ATOM   3587 N  N     . GLU B 1 164 ? 100.178 72.669  111.266 1.00 37.68 ? 164 GLU B N     1 
ATOM   3588 C  CA    . GLU B 1 164 ? 99.495  71.737  110.372 1.00 37.68 ? 164 GLU B CA    1 
ATOM   3589 C  C     . GLU B 1 164 ? 100.462 70.870  109.573 1.00 37.68 ? 164 GLU B C     1 
ATOM   3590 O  O     . GLU B 1 164 ? 100.133 69.727  109.245 1.00 37.68 ? 164 GLU B O     1 
ATOM   3591 C  CB    . GLU B 1 164 ? 98.584  72.510  109.418 1.00 37.68 ? 164 GLU B CB    1 
ATOM   3592 C  CG    . GLU B 1 164 ? 97.671  71.624  108.570 1.00 37.68 ? 164 GLU B CG    1 
ATOM   3593 C  CD    . GLU B 1 164 ? 96.776  70.721  109.374 1.00 37.68 ? 164 GLU B CD    1 
ATOM   3594 O  OE1   . GLU B 1 164 ? 96.235  71.165  110.403 1.00 37.68 ? 164 GLU B OE1   1 
ATOM   3595 O  OE2   . GLU B 1 164 ? 96.608  69.554  108.978 1.00 37.68 ? 164 GLU B OE2   1 
ATOM   3596 N  N     . LEU B 1 165 ? 101.650 71.382  109.255 1.00 36.16 ? 165 LEU B N     1 
ATOM   3597 C  CA    . LEU B 1 165 ? 102.634 70.594  108.517 1.00 36.16 ? 165 LEU B CA    1 
ATOM   3598 C  C     . LEU B 1 165 ? 103.064 69.329  109.240 1.00 36.16 ? 165 LEU B C     1 
ATOM   3599 O  O     . LEU B 1 165 ? 103.656 68.447  108.612 1.00 36.16 ? 165 LEU B O     1 
ATOM   3600 C  CB    . LEU B 1 165 ? 103.865 71.426  108.195 1.00 36.16 ? 165 LEU B CB    1 
ATOM   3601 C  CG    . LEU B 1 165 ? 103.716 72.400  107.038 1.00 36.16 ? 165 LEU B CG    1 
ATOM   3602 C  CD1   . LEU B 1 165 ? 104.863 73.362  107.046 1.00 36.16 ? 165 LEU B CD1   1 
ATOM   3603 C  CD2   . LEU B 1 165 ? 103.659 71.664  105.726 1.00 36.16 ? 165 LEU B CD2   1 
ATOM   3604 N  N     . GLU B 1 166 ? 102.794 69.213  110.537 1.00 42.96 ? 166 GLU B N     1 
ATOM   3605 C  CA    . GLU B 1 166 ? 103.122 67.986  111.252 1.00 42.96 ? 166 GLU B CA    1 
ATOM   3606 C  C     . GLU B 1 166 ? 102.410 66.768  110.676 1.00 42.96 ? 166 GLU B C     1 
ATOM   3607 O  O     . GLU B 1 166 ? 102.865 65.636  110.881 1.00 42.96 ? 166 GLU B O     1 
ATOM   3608 C  CB    . GLU B 1 166 ? 102.751 68.135  112.722 1.00 42.96 ? 166 GLU B CB    1 
ATOM   3609 C  CG    . GLU B 1 166 ? 103.481 69.244  113.445 1.00 42.96 ? 166 GLU B CG    1 
ATOM   3610 C  CD    . GLU B 1 166 ? 104.977 69.068  113.488 1.00 42.96 ? 166 GLU B CD    1 
ATOM   3611 O  OE1   . GLU B 1 166 ? 105.458 67.920  113.374 1.00 42.96 ? 166 GLU B OE1   1 
ATOM   3612 O  OE2   . GLU B 1 166 ? 105.675 70.095  113.643 1.00 42.96 ? 166 GLU B OE2   1 
ATOM   3613 N  N     . ASN B 1 167 ? 101.282 66.975  110.008 1.00 40.67 ? 167 ASN B N     1 
ATOM   3614 C  CA    . ASN B 1 167 ? 100.479 65.930  109.393 1.00 40.67 ? 167 ASN B CA    1 
ATOM   3615 C  C     . ASN B 1 167 ? 100.884 65.602  107.961 1.00 40.67 ? 167 ASN B C     1 
ATOM   3616 O  O     . ASN B 1 167 ? 100.187 64.818  107.308 1.00 40.67 ? 167 ASN B O     1 
ATOM   3617 C  CB    . ASN B 1 167 ? 99.009  66.338  109.437 1.00 40.67 ? 167 ASN B CB    1 
ATOM   3618 C  CG    . ASN B 1 167 ? 98.551  66.683  110.838 1.00 40.67 ? 167 ASN B CG    1 
ATOM   3619 O  OD1   . ASN B 1 167 ? 98.878  65.985  111.795 1.00 40.67 ? 167 ASN B OD1   1 
ATOM   3620 N  ND2   . ASN B 1 167 ? 97.811  67.781  110.971 1.00 40.67 ? 167 ASN B ND2   1 
ATOM   3621 N  N     . HIS B 1 168 ? 101.998 66.141  107.469 1.00 36.19 ? 168 HIS B N     1 
ATOM   3622 C  CA    . HIS B 1 168 ? 102.416 65.969  106.074 1.00 36.19 ? 168 HIS B CA    1 
ATOM   3623 C  C     . HIS B 1 168 ? 103.757 65.272  105.944 1.00 36.19 ? 168 HIS B C     1 
ATOM   3624 O  O     . HIS B 1 168 ? 104.808 65.908  106.123 1.00 36.19 ? 168 HIS B O     1 
ATOM   3625 C  CB    . HIS B 1 168 ? 102.463 67.319  105.378 1.00 36.19 ? 168 HIS B CB    1 
ATOM   3626 C  CG    . HIS B 1 168 ? 101.116 67.875  105.091 1.00 36.19 ? 168 HIS B CG    1 
ATOM   3627 N  ND1   . HIS B 1 168 ? 100.341 67.439  104.041 1.00 36.19 ? 168 HIS B ND1   1 
ATOM   3628 C  CD2   . HIS B 1 168 ? 100.391 68.821  105.731 1.00 36.19 ? 168 HIS B CD2   1 
ATOM   3629 C  CE1   . HIS B 1 168 ? 99.200  68.102  104.037 1.00 36.19 ? 168 HIS B CE1   1 
ATOM   3630 N  NE2   . HIS B 1 168 ? 99.204  68.944  105.054 1.00 36.19 ? 168 HIS B NE2   1 
ATOM   3631 N  N     . PRO B 1 169 ? 103.764 63.969  105.643 1.00 36.21 ? 169 PRO B N     1 
ATOM   3632 C  CA    . PRO B 1 169 ? 105.022 63.212  105.548 1.00 36.21 ? 169 PRO B CA    1 
ATOM   3633 C  C     . PRO B 1 169 ? 106.114 63.845  104.707 1.00 36.21 ? 169 PRO B C     1 
ATOM   3634 O  O     . PRO B 1 169 ? 107.283 63.779  105.095 1.00 36.21 ? 169 PRO B O     1 
ATOM   3635 C  CB    . PRO B 1 169 ? 104.563 61.888  104.927 1.00 36.21 ? 169 PRO B CB    1 
ATOM   3636 C  CG    . PRO B 1 169 ? 103.186 61.725  105.379 1.00 36.21 ? 169 PRO B CG    1 
ATOM   3637 C  CD    . PRO B 1 169 ? 102.595 63.111  105.410 1.00 36.21 ? 169 PRO B CD    1 
ATOM   3638 N  N     . VAL B 1 170 ? 105.780 64.460  103.572 1.00 34.84 ? 170 VAL B N     1 
ATOM   3639 C  CA    . VAL B 1 170 ? 106.798 65.089  102.738 1.00 34.84 ? 170 VAL B CA    1 
ATOM   3640 C  C     . VAL B 1 170 ? 107.504 66.221  103.462 1.00 34.84 ? 170 VAL B C     1 
ATOM   3641 O  O     . VAL B 1 170 ? 108.629 66.577  103.108 1.00 34.84 ? 170 VAL B O     1 
ATOM   3642 C  CB    . VAL B 1 170 ? 106.181 65.561  101.404 1.00 34.84 ? 170 VAL B CB    1 
ATOM   3643 C  CG1   . VAL B 1 170 ? 105.302 66.737  101.615 1.00 34.84 ? 170 VAL B CG1   1 
ATOM   3644 C  CG2   . VAL B 1 170 ? 107.257 65.906  100.408 1.00 34.84 ? 170 VAL B CG2   1 
ATOM   3645 N  N     . TYR B 1 171 ? 106.875 66.816  104.465 1.00 34.05 ? 171 TYR B N     1 
ATOM   3646 C  CA    . TYR B 1 171 ? 107.576 67.838  105.236 1.00 34.05 ? 171 TYR B CA    1 
ATOM   3647 C  C     . TYR B 1 171 ? 108.486 67.213  106.290 1.00 34.05 ? 171 TYR B C     1 
ATOM   3648 O  O     . TYR B 1 171 ? 109.711 67.294  106.200 1.00 34.05 ? 171 TYR B O     1 
ATOM   3649 C  CB    . TYR B 1 171 ? 106.582 68.791  105.892 1.00 34.05 ? 171 TYR B CB    1 
ATOM   3650 C  CG    . TYR B 1 171 ? 107.262 69.829  106.732 1.00 34.05 ? 171 TYR B CG    1 
ATOM   3651 C  CD1   . TYR B 1 171 ? 107.940 70.865  106.139 1.00 34.05 ? 171 TYR B CD1   1 
ATOM   3652 C  CD2   . TYR B 1 171 ? 107.258 69.755  108.113 1.00 34.05 ? 171 TYR B CD2   1 
ATOM   3653 C  CE1   . TYR B 1 171 ? 108.569 71.820  106.884 1.00 34.05 ? 171 TYR B CE1   1 
ATOM   3654 C  CE2   . TYR B 1 171 ? 107.889 70.706  108.871 1.00 34.05 ? 171 TYR B CE2   1 
ATOM   3655 C  CZ    . TYR B 1 171 ? 108.545 71.741  108.247 1.00 34.05 ? 171 TYR B CZ    1 
ATOM   3656 O  OH    . TYR B 1 171 ? 109.178 72.718  108.978 1.00 34.05 ? 171 TYR B OH    1 
ATOM   3657 N  N     . THR B 1 172 ? 107.890 66.554  107.281 1.00 38.08 ? 172 THR B N     1 
ATOM   3658 C  CA    . THR B 1 172 ? 108.653 66.016  108.405 1.00 38.08 ? 172 THR B CA    1 
ATOM   3659 C  C     . THR B 1 172 ? 109.707 65.000  107.985 1.00 38.08 ? 172 THR B C     1 
ATOM   3660 O  O     . THR B 1 172 ? 110.793 64.960  108.572 1.00 38.08 ? 172 THR B O     1 
ATOM   3661 C  CB    . THR B 1 172 ? 107.698 65.391  109.418 1.00 38.08 ? 172 THR B CB    1 
ATOM   3662 O  OG1   . THR B 1 172 ? 107.007 64.297  108.810 1.00 38.08 ? 172 THR B OG1   1 
ATOM   3663 C  CG2   . THR B 1 172 ? 106.681 66.407  109.881 1.00 38.08 ? 172 THR B CG2   1 
ATOM   3664 N  N     . GLN B 1 173 ? 109.433 64.191  106.967 1.00 39.11 ? 173 GLN B N     1 
ATOM   3665 C  CA    . GLN B 1 173 ? 110.396 63.175  106.550 1.00 39.11 ? 173 GLN B CA    1 
ATOM   3666 C  C     . GLN B 1 173 ? 111.417 63.647  105.526 1.00 39.11 ? 173 GLN B C     1 
ATOM   3667 O  O     . GLN B 1 173 ? 112.435 62.977  105.352 1.00 39.11 ? 173 GLN B O     1 
ATOM   3668 C  CB    . GLN B 1 173 ? 109.669 61.919  106.072 1.00 39.11 ? 173 GLN B CB    1 
ATOM   3669 C  CG    . GLN B 1 173 ? 108.740 61.400  107.157 1.00 39.11 ? 173 GLN B CG    1 
ATOM   3670 C  CD    . GLN B 1 173 ? 108.242 59.993  106.923 1.00 39.11 ? 173 GLN B CD    1 
ATOM   3671 O  OE1   . GLN B 1 173 ? 108.677 59.310  105.999 1.00 39.11 ? 173 GLN B OE1   1 
ATOM   3672 N  NE2   . GLN B 1 173 ? 107.332 59.543  107.781 1.00 39.11 ? 173 GLN B NE2   1 
ATOM   3673 N  N     . TRP B 1 174 ? 111.207 64.774  104.852 1.00 35.54 ? 174 TRP B N     1 
ATOM   3674 C  CA    . TRP B 1 174 ? 112.203 65.179  103.867 1.00 35.54 ? 174 TRP B CA    1 
ATOM   3675 C  C     . TRP B 1 174 ? 112.486 66.674  103.844 1.00 35.54 ? 174 TRP B C     1 
ATOM   3676 O  O     . TRP B 1 174 ? 113.610 67.085  104.139 1.00 35.54 ? 174 TRP B O     1 
ATOM   3677 C  CB    . TRP B 1 174 ? 111.816 64.702  102.465 1.00 35.54 ? 174 TRP B CB    1 
ATOM   3678 C  CG    . TRP B 1 174 ? 112.869 65.048  101.458 1.00 35.54 ? 174 TRP B CG    1 
ATOM   3679 C  CD1   . TRP B 1 174 ? 114.165 64.656  101.481 1.00 35.54 ? 174 TRP B CD1   1 
ATOM   3680 C  CD2   . TRP B 1 174 ? 112.706 65.817  100.263 1.00 35.54 ? 174 TRP B CD2   1 
ATOM   3681 N  NE1   . TRP B 1 174 ? 114.833 65.163  100.405 1.00 35.54 ? 174 TRP B NE1   1 
ATOM   3682 C  CE2   . TRP B 1 174 ? 113.956 65.876  99.636  1.00 35.54 ? 174 TRP B CE2   1 
ATOM   3683 C  CE3   . TRP B 1 174 ? 111.627 66.470  99.669  1.00 35.54 ? 174 TRP B CE3   1 
ATOM   3684 C  CZ2   . TRP B 1 174 ? 114.157 66.553  98.448  1.00 35.54 ? 174 TRP B CZ2   1 
ATOM   3685 C  CZ3   . TRP B 1 174 ? 111.831 67.144  98.492  1.00 35.54 ? 174 TRP B CZ3   1 
ATOM   3686 C  CH2   . TRP B 1 174 ? 113.082 67.182  97.894  1.00 35.54 ? 174 TRP B CH2   1 
ATOM   3687 N  N     . LEU B 1 175 ? 111.508 67.495  103.480 1.00 33.24 ? 175 LEU B N     1 
ATOM   3688 C  CA    . LEU B 1 175 ? 111.758 68.928  103.359 1.00 33.24 ? 175 LEU B CA    1 
ATOM   3689 C  C     . LEU B 1 175 ? 112.207 69.564  104.664 1.00 33.24 ? 175 LEU B C     1 
ATOM   3690 O  O     . LEU B 1 175 ? 112.855 70.612  104.645 1.00 33.24 ? 175 LEU B O     1 
ATOM   3691 C  CB    . LEU B 1 175 ? 110.499 69.628  102.864 1.00 33.24 ? 175 LEU B CB    1 
ATOM   3692 C  CG    . LEU B 1 175 ? 109.998 69.214  101.493 1.00 33.24 ? 175 LEU B CG    1 
ATOM   3693 C  CD1   . LEU B 1 175 ? 108.585 69.693  101.330 1.00 33.24 ? 175 LEU B CD1   1 
ATOM   3694 C  CD2   . LEU B 1 175 ? 110.878 69.801  100.445 1.00 33.24 ? 175 LEU B CD2   1 
ATOM   3695 N  N     . GLN B 1 176 ? 111.855 68.979  105.803 1.00 35.74 ? 176 GLN B N     1 
ATOM   3696 C  CA    . GLN B 1 176 ? 112.275 69.544  107.082 1.00 35.74 ? 176 GLN B CA    1 
ATOM   3697 C  C     . GLN B 1 176 ? 113.783 69.516  107.275 1.00 35.74 ? 176 GLN B C     1 
ATOM   3698 O  O     . GLN B 1 176 ? 114.337 70.404  107.928 1.00 35.74 ? 176 GLN B O     1 
ATOM   3699 C  CB    . GLN B 1 176 ? 111.576 68.813  108.221 1.00 35.74 ? 176 GLN B CB    1 
ATOM   3700 C  CG    . GLN B 1 176 ? 111.893 69.356  109.580 1.00 35.74 ? 176 GLN B CG    1 
ATOM   3701 C  CD    . GLN B 1 176 ? 110.936 68.854  110.630 1.00 35.74 ? 176 GLN B CD    1 
ATOM   3702 O  OE1   . GLN B 1 176 ? 110.372 69.638  111.390 1.00 35.74 ? 176 GLN B OE1   1 
ATOM   3703 N  NE2   . GLN B 1 176 ? 110.740 67.548  110.678 1.00 35.74 ? 176 GLN B NE2   1 
ATOM   3704 N  N     . HIS B 1 177 ? 114.467 68.539  106.696 1.00 37.16 ? 177 HIS B N     1 
ATOM   3705 C  CA    . HIS B 1 177 ? 115.897 68.389  106.901 1.00 37.16 ? 177 HIS B CA    1 
ATOM   3706 C  C     . HIS B 1 177 ? 116.760 69.228  105.973 1.00 37.16 ? 177 HIS B C     1 
ATOM   3707 O  O     . HIS B 1 177 ? 117.939 69.435  106.273 1.00 37.16 ? 177 HIS B O     1 
ATOM   3708 C  CB    . HIS B 1 177 ? 116.251 66.914  106.745 1.00 37.16 ? 177 HIS B CB    1 
ATOM   3709 C  CG    . HIS B 1 177 ? 115.442 66.025  107.634 1.00 37.16 ? 177 HIS B CG    1 
ATOM   3710 N  ND1   . HIS B 1 177 ? 115.560 66.036  109.005 1.00 37.16 ? 177 HIS B ND1   1 
ATOM   3711 C  CD2   . HIS B 1 177 ? 114.489 65.111  107.344 1.00 37.16 ? 177 HIS B CD2   1 
ATOM   3712 C  CE1   . HIS B 1 177 ? 114.711 65.167  109.523 1.00 37.16 ? 177 HIS B CE1   1 
ATOM   3713 N  NE2   . HIS B 1 177 ? 114.051 64.591  108.536 1.00 37.16 ? 177 HIS B NE2   1 
ATOM   3714 N  N     . ILE B 1 178 ? 116.212 69.707  104.863 1.00 32.42 ? 178 ILE B N     1 
ATOM   3715 C  CA    . ILE B 1 178 ? 116.951 70.508  103.893 1.00 32.42 ? 178 ILE B CA    1 
ATOM   3716 C  C     . ILE B 1 178 ? 117.190 71.914  104.423 1.00 32.42 ? 178 ILE B C     1 
ATOM   3717 O  O     . ILE B 1 178 ? 116.250 72.606  104.824 1.00 32.42 ? 178 ILE B O     1 
ATOM   3718 C  CB    . ILE B 1 178 ? 116.204 70.546  102.557 1.00 32.42 ? 178 ILE B CB    1 
ATOM   3719 C  CG1   . ILE B 1 178 ? 116.169 69.145  101.956 1.00 32.42 ? 178 ILE B CG1   1 
ATOM   3720 C  CG2   . ILE B 1 178 ? 116.839 71.547  101.618 1.00 32.42 ? 178 ILE B CG2   1 
ATOM   3721 C  CD1   . ILE B 1 178 ? 115.278 69.011  100.768 1.00 32.42 ? 178 ILE B CD1   1 
ATOM   3722 N  N     . LYS B 1 179 ? 118.455 72.323  104.477 1.00 28.64 ? 179 LYS B N     1 
ATOM   3723 C  CA    . LYS B 1 179 ? 118.785 73.682  104.897 1.00 28.64 ? 179 LYS B CA    1 
ATOM   3724 C  C     . LYS B 1 179 ? 118.127 74.697  103.971 1.00 28.64 ? 179 LYS B C     1 
ATOM   3725 O  O     . LYS B 1 179 ? 118.208 74.576  102.752 1.00 28.64 ? 179 LYS B O     1 
ATOM   3726 C  CB    . LYS B 1 179 ? 120.295 73.898  104.893 1.00 28.64 ? 179 LYS B CB    1 
ATOM   3727 C  CG    . LYS B 1 179 ? 120.681 75.261  105.422 1.00 28.64 ? 179 LYS B CG    1 
ATOM   3728 C  CD    . LYS B 1 179 ? 122.179 75.480  105.456 1.00 28.64 ? 179 LYS B CD    1 
ATOM   3729 C  CE    . LYS B 1 179 ? 122.470 76.913  105.852 1.00 28.64 ? 179 LYS B CE    1 
ATOM   3730 N  NZ    . LYS B 1 179 ? 123.889 77.189  106.135 1.00 28.64 ? 179 LYS B NZ    1 
ATOM   3731 N  N     . GLY B 1 180 ? 117.481 75.704  104.545 1.00 26.93 ? 180 GLY B N     1 
ATOM   3732 C  CA    . GLY B 1 180 ? 116.802 76.715  103.765 1.00 26.93 ? 180 GLY B CA    1 
ATOM   3733 C  C     . GLY B 1 180 ? 115.337 76.453  103.491 1.00 26.93 ? 180 GLY B C     1 
ATOM   3734 O  O     . GLY B 1 180 ? 114.688 77.284  102.853 1.00 26.93 ? 180 GLY B O     1 
ATOM   3735 N  N     . ILE B 1 181 ? 114.785 75.347  103.979 1.00 29.87 ? 181 ILE B N     1 
ATOM   3736 C  CA    . ILE B 1 181 ? 113.364 75.037  103.865 1.00 29.87 ? 181 ILE B CA    1 
ATOM   3737 C  C     . ILE B 1 181 ? 112.717 75.131  105.237 1.00 29.87 ? 181 ILE B C     1 
ATOM   3738 O  O     . ILE B 1 181 ? 113.230 74.573  106.213 1.00 29.87 ? 181 ILE B O     1 
ATOM   3739 C  CB    . ILE B 1 181 ? 113.140 73.649  103.243 1.00 29.87 ? 181 ILE B CB    1 
ATOM   3740 C  CG1   . ILE B 1 181 ? 113.669 73.628  101.811 1.00 29.87 ? 181 ILE B CG1   1 
ATOM   3741 C  CG2   . ILE B 1 181 ? 111.679 73.223  103.345 1.00 29.87 ? 181 ILE B CG2   1 
ATOM   3742 C  CD1   . ILE B 1 181 ? 113.364 72.377  101.087 1.00 29.87 ? 181 ILE B CD1   1 
ATOM   3743 N  N     . GLY B 1 182 ? 111.603 75.853  105.314 1.00 29.81 ? 182 GLY B N     1 
ATOM   3744 C  CA    . GLY B 1 182 ? 110.843 75.998  106.531 1.00 29.81 ? 182 GLY B CA    1 
ATOM   3745 C  C     . GLY B 1 182 ? 109.359 75.821  106.286 1.00 29.81 ? 182 GLY B C     1 
ATOM   3746 O  O     . GLY B 1 182 ? 108.946 75.237  105.286 1.00 29.81 ? 182 GLY B O     1 
ATOM   3747 N  N     . PRO B 1 183 ? 108.529 76.305  107.211 1.00 30.04 ? 183 PRO B N     1 
ATOM   3748 C  CA    . PRO B 1 183 ? 107.074 76.152  107.062 1.00 30.04 ? 183 PRO B CA    1 
ATOM   3749 C  C     . PRO B 1 183 ? 106.441 76.872  105.878 1.00 30.04 ? 183 PRO B C     1 
ATOM   3750 O  O     . PRO B 1 183 ? 105.469 76.353  105.324 1.00 30.04 ? 183 PRO B O     1 
ATOM   3751 C  CB    . PRO B 1 183 ? 106.539 76.737  108.371 1.00 30.04 ? 183 PRO B CB    1 
ATOM   3752 C  CG    . PRO B 1 183 ? 107.625 76.622  109.308 1.00 30.04 ? 183 PRO B CG    1 
ATOM   3753 C  CD    . PRO B 1 183 ? 108.864 76.879  108.517 1.00 30.04 ? 183 PRO B CD    1 
ATOM   3754 N  N     . VAL B 1 184 ? 106.934 78.037  105.464 1.00 24.20 ? 184 VAL B N     1 
ATOM   3755 C  CA    . VAL B 1 184 ? 106.284 78.748  104.367 1.00 24.20 ? 184 VAL B CA    1 
ATOM   3756 C  C     . VAL B 1 184 ? 106.653 78.149  103.016 1.00 24.20 ? 184 VAL B C     1 
ATOM   3757 O  O     . VAL B 1 184 ? 105.781 77.916  102.176 1.00 24.20 ? 184 VAL B O     1 
ATOM   3758 C  CB    . VAL B 1 184 ? 106.613 80.249  104.427 1.00 24.20 ? 184 VAL B CB    1 
ATOM   3759 C  CG1   . VAL B 1 184 ? 106.023 80.964  103.247 1.00 24.20 ? 184 VAL B CG1   1 
ATOM   3760 C  CG2   . VAL B 1 184 ? 106.073 80.833  105.694 1.00 24.20 ? 184 VAL B CG2   1 
ATOM   3761 N  N     . VAL B 1 185 ? 107.935 77.866  102.791 1.00 23.38 ? 185 VAL B N     1 
ATOM   3762 C  CA    . VAL B 1 185 ? 108.348 77.217  101.548 1.00 23.38 ? 185 VAL B CA    1 
ATOM   3763 C  C     . VAL B 1 185 ? 107.610 75.900  101.368 1.00 23.38 ? 185 VAL B C     1 
ATOM   3764 O  O     . VAL B 1 185 ? 107.025 75.633  100.313 1.00 23.38 ? 185 VAL B O     1 
ATOM   3765 C  CB    . VAL B 1 185 ? 109.873 77.014  101.517 1.00 23.38 ? 185 VAL B CB    1 
ATOM   3766 C  CG1   . VAL B 1 185 ? 110.241 75.949  100.512 1.00 23.38 ? 185 VAL B CG1   1 
ATOM   3767 C  CG2   . VAL B 1 185 ? 110.566 78.298  101.173 1.00 23.38 ? 185 VAL B CG2   1 
ATOM   3768 N  N     . ALA B 1 186 ? 107.596 75.072  102.408 1.00 24.48 ? 186 ALA B N     1 
ATOM   3769 C  CA    . ALA B 1 186 ? 106.974 73.765  102.290 1.00 24.48 ? 186 ALA B CA    1 
ATOM   3770 C  C     . ALA B 1 186 ? 105.465 73.864  102.214 1.00 24.48 ? 186 ALA B C     1 
ATOM   3771 O  O     . ALA B 1 186 ? 104.838 73.133  101.439 1.00 24.48 ? 186 ALA B O     1 
ATOM   3772 C  CB    . ALA B 1 186 ? 107.392 72.887  103.458 1.00 24.48 ? 186 ALA B CB    1 
ATOM   3773 N  N     . GLY B 1 187 ? 104.859 74.738  103.014 1.00 24.44 ? 187 GLY B N     1 
ATOM   3774 C  CA    . GLY B 1 187 ? 103.419 74.903  102.952 1.00 24.44 ? 187 GLY B CA    1 
ATOM   3775 C  C     . GLY B 1 187 ? 102.952 75.354  101.586 1.00 24.44 ? 187 GLY B C     1 
ATOM   3776 O  O     . GLY B 1 187 ? 102.000 74.798  101.029 1.00 24.44 ? 187 GLY B O     1 
ATOM   3777 N  N     . GLY B 1 188 ? 103.676 76.299  100.988 1.00 21.46 ? 188 GLY B N     1 
ATOM   3778 C  CA    . GLY B 1 188 ? 103.320 76.776  99.668  1.00 21.46 ? 188 GLY B CA    1 
ATOM   3779 C  C     . GLY B 1 188 ? 103.518 75.733  98.594  1.00 21.46 ? 188 GLY B C     1 
ATOM   3780 O  O     . GLY B 1 188 ? 102.667 75.567  97.727  1.00 21.46 ? 188 GLY B O     1 
ATOM   3781 N  N     . LEU B 1 189 ? 104.639 75.022  98.628  1.00 23.40 ? 189 LEU B N     1 
ATOM   3782 C  CA    . LEU B 1 189 ? 104.885 73.981  97.642  1.00 23.40 ? 189 LEU B CA    1 
ATOM   3783 C  C     . LEU B 1 189 ? 103.833 72.876  97.702  1.00 23.40 ? 189 LEU B C     1 
ATOM   3784 O  O     . LEU B 1 189 ? 103.251 72.495  96.674  1.00 23.40 ? 189 LEU B O     1 
ATOM   3785 C  CB    . LEU B 1 189 ? 106.285 73.416  97.872  1.00 23.40 ? 189 LEU B CB    1 
ATOM   3786 C  CG    . LEU B 1 189 ? 106.837 72.326  96.979  1.00 23.40 ? 189 LEU B CG    1 
ATOM   3787 C  CD1   . LEU B 1 189 ? 107.118 72.879  95.622  1.00 23.40 ? 189 LEU B CD1   1 
ATOM   3788 C  CD2   . LEU B 1 189 ? 108.095 71.867  97.609  1.00 23.40 ? 189 LEU B CD2   1 
ATOM   3789 N  N     . ILE B 1 190 ? 103.522 72.401  98.908  1.00 24.07 ? 190 ILE B N     1 
ATOM   3790 C  CA    . ILE B 1 190 ? 102.526 71.347  99.069  1.00 24.07 ? 190 ILE B CA    1 
ATOM   3791 C  C     . ILE B 1 190 ? 101.158 71.815  98.589  1.00 24.07 ? 190 ILE B C     1 
ATOM   3792 O  O     . ILE B 1 190 ? 100.534 71.176  97.737  1.00 24.07 ? 190 ILE B O     1 
ATOM   3793 C  CB    . ILE B 1 190 ? 102.477 70.851  100.525 1.00 24.07 ? 190 ILE B CB    1 
ATOM   3794 C  CG1   . ILE B 1 190 ? 103.754 70.097  100.890 1.00 24.07 ? 190 ILE B CG1   1 
ATOM   3795 C  CG2   . ILE B 1 190 ? 101.310 69.925  100.732 1.00 24.07 ? 190 ILE B CG2   1 
ATOM   3796 C  CD1   . ILE B 1 190 ? 103.968 69.947  102.368 1.00 24.07 ? 190 ILE B CD1   1 
ATOM   3797 N  N     . SER B 1 191 ? 100.658 72.926  99.126  1.00 23.46 ? 191 SER B N     1 
ATOM   3798 C  CA    . SER B 1 191 ? 99.317  73.333  98.727  1.00 23.46 ? 191 SER B CA    1 
ATOM   3799 C  C     . SER B 1 191 ? 99.215  73.811  97.274  1.00 23.46 ? 191 SER B C     1 
ATOM   3800 O  O     . SER B 1 191 ? 98.171  73.605  96.649  1.00 23.46 ? 191 SER B O     1 
ATOM   3801 C  CB    . SER B 1 191 ? 98.791  74.387  99.689  1.00 23.46 ? 191 SER B CB    1 
ATOM   3802 O  OG    . SER B 1 191 ? 99.543  75.566  99.617  1.00 23.46 ? 191 SER B OG    1 
ATOM   3803 N  N     . LEU B 1 192 ? 100.250 74.435  96.701  1.00 21.59 ? 192 LEU B N     1 
ATOM   3804 C  CA    . LEU B 1 192 ? 100.168 74.847  95.300  1.00 21.59 ? 192 LEU B CA    1 
ATOM   3805 C  C     . LEU B 1 192 ? 100.177 73.662  94.346  1.00 21.59 ? 192 LEU B C     1 
ATOM   3806 O  O     . LEU B 1 192 ? 99.493  73.685  93.323  1.00 21.59 ? 192 LEU B O     1 
ATOM   3807 C  CB    . LEU B 1 192 ? 101.301 75.802  94.956  1.00 21.59 ? 192 LEU B CB    1 
ATOM   3808 C  CG    . LEU B 1 192 ? 101.181 77.191  95.556  1.00 21.59 ? 192 LEU B CG    1 
ATOM   3809 C  CD1   . LEU B 1 192 ? 102.460 77.925  95.381  1.00 21.59 ? 192 LEU B CD1   1 
ATOM   3810 C  CD2   . LEU B 1 192 ? 100.083 77.909  94.857  1.00 21.59 ? 192 LEU B CD2   1 
ATOM   3811 N  N     . ILE B 1 193 ? 100.911 72.607  94.662  1.00 25.13 ? 193 ILE B N     1 
ATOM   3812 C  CA    . ILE B 1 193 ? 100.922 71.475  93.744  1.00 25.13 ? 193 ILE B CA    1 
ATOM   3813 C  C     . ILE B 1 193 ? 99.725  70.558  93.982  1.00 25.13 ? 193 ILE B C     1 
ATOM   3814 O  O     . ILE B 1 193 ? 99.116  70.060  93.031  1.00 25.13 ? 193 ILE B O     1 
ATOM   3815 C  CB    . ILE B 1 193 ? 102.269 70.735  93.830  1.00 25.13 ? 193 ILE B CB    1 
ATOM   3816 C  CG1   . ILE B 1 193 ? 103.379 71.693  93.401  1.00 25.13 ? 193 ILE B CG1   1 
ATOM   3817 C  CG2   . ILE B 1 193 ? 102.262 69.443  93.032  1.00 25.13 ? 193 ILE B CG2   1 
ATOM   3818 C  CD1   . ILE B 1 193 ? 104.745 71.190  93.644  1.00 25.13 ? 193 ILE B CD1   1 
ATOM   3819 N  N     . GLY B 1 194 ? 99.367  70.329  95.230  1.00 30.35 ? 194 GLY B N     1 
ATOM   3820 C  CA    . GLY B 1 194 ? 98.297  69.426  95.586  1.00 30.35 ? 194 GLY B CA    1 
ATOM   3821 C  C     . GLY B 1 194 ? 98.768  67.991  95.507  1.00 30.35 ? 194 GLY B C     1 
ATOM   3822 O  O     . GLY B 1 194 ? 99.963  67.722  95.603  1.00 30.35 ? 194 GLY B O     1 
ATOM   3823 N  N     . ASP B 1 195 ? 97.831  67.058  95.343  1.00 37.78 ? 195 ASP B N     1 
ATOM   3824 C  CA    . ASP B 1 195 ? 98.224  65.655  95.232  1.00 37.78 ? 195 ASP B CA    1 
ATOM   3825 C  C     . ASP B 1 195 ? 99.123  65.396  94.035  1.00 37.78 ? 195 ASP B C     1 
ATOM   3826 O  O     . ASP B 1 195 ? 98.825  65.800  92.911  1.00 37.78 ? 195 ASP B O     1 
ATOM   3827 C  CB    . ASP B 1 195 ? 97.015  64.719  95.192  1.00 37.78 ? 195 ASP B CB    1 
ATOM   3828 C  CG    . ASP B 1 195 ? 96.237  64.711  96.484  1.00 37.78 ? 195 ASP B CG    1 
ATOM   3829 O  OD1   . ASP B 1 195 ? 96.849  64.967  97.540  1.00 37.78 ? 195 ASP B OD1   1 
ATOM   3830 O  OD2   . ASP B 1 195 ? 95.037  64.374  96.464  1.00 37.78 ? 195 ASP B OD2   1 
ATOM   3831 N  N     . ILE B 1 196 ? 100.224 64.687  94.292  1.00 37.42 ? 196 ILE B N     1 
ATOM   3832 C  CA    . ILE B 1 196 ? 101.193 64.351  93.254  1.00 37.42 ? 196 ILE B CA    1 
ATOM   3833 C  C     . ILE B 1 196 ? 100.762 63.190  92.369  1.00 37.42 ? 196 ILE B C     1 
ATOM   3834 O  O     . ILE B 1 196 ? 101.486 62.849  91.427  1.00 37.42 ? 196 ILE B O     1 
ATOM   3835 C  CB    . ILE B 1 196 ? 102.544 64.053  93.933  1.00 37.42 ? 196 ILE B CB    1 
ATOM   3836 C  CG1   . ILE B 1 196 ? 103.702 64.313  92.971  1.00 37.42 ? 196 ILE B CG1   1 
ATOM   3837 C  CG2   . ILE B 1 196 ? 102.543 62.657  94.456  1.00 37.42 ? 196 ILE B CG2   1 
ATOM   3838 C  CD1   . ILE B 1 196 ? 104.067 65.790  92.809  1.00 37.42 ? 196 ILE B CD1   1 
ATOM   3839 N  N     . ASP B 1 197 ? 99.601  62.583  92.613  1.00 40.63 ? 197 ASP B N     1 
ATOM   3840 C  CA    . ASP B 1 197 ? 99.122  61.537  91.714  1.00 40.63 ? 197 ASP B CA    1 
ATOM   3841 C  C     . ASP B 1 197 ? 98.531  62.130  90.444  1.00 40.63 ? 197 ASP B C     1 
ATOM   3842 O  O     . ASP B 1 197 ? 98.216  61.392  89.510  1.00 40.63 ? 197 ASP B O     1 
ATOM   3843 C  CB    . ASP B 1 197 ? 98.109  60.617  92.395  1.00 40.63 ? 197 ASP B CB    1 
ATOM   3844 C  CG    . ASP B 1 197 ? 96.815  61.304  92.721  1.00 40.63 ? 197 ASP B CG    1 
ATOM   3845 O  OD1   . ASP B 1 197 ? 96.803  62.537  92.859  1.00 40.63 ? 197 ASP B OD1   1 
ATOM   3846 O  OD2   . ASP B 1 197 ? 95.793  60.598  92.837  1.00 40.63 ? 197 ASP B OD2   1 
ATOM   3847 N  N     . ARG B 1 198 ? 98.334  63.441  90.418  1.00 32.42 ? 198 ARG B N     1 
ATOM   3848 C  CA    . ARG B 1 198 ? 97.845  64.173  89.265  1.00 32.42 ? 198 ARG B CA    1 
ATOM   3849 C  C     . ARG B 1 198 ? 98.866  64.266  88.148  1.00 32.42 ? 198 ARG B C     1 
ATOM   3850 O  O     . ARG B 1 198 ? 98.492  64.593  87.022  1.00 32.42 ? 198 ARG B O     1 
ATOM   3851 C  CB    . ARG B 1 198 ? 97.456  65.576  89.714  1.00 32.42 ? 198 ARG B CB    1 
ATOM   3852 C  CG    . ARG B 1 198 ? 96.291  65.591  90.656  1.00 32.42 ? 198 ARG B CG    1 
ATOM   3853 C  CD    . ARG B 1 198 ? 95.583  66.935  90.698  1.00 32.42 ? 198 ARG B CD    1 
ATOM   3854 N  NE    . ARG B 1 198 ? 96.487  68.025  91.035  1.00 32.42 ? 198 ARG B NE    1 
ATOM   3855 C  CZ    . ARG B 1 198 ? 96.389  69.265  90.578  1.00 32.42 ? 198 ARG B CZ    1 
ATOM   3856 N  NH1   . ARG B 1 198 ? 95.504  69.596  89.658  1.00 32.42 ? 198 ARG B NH1   1 
ATOM   3857 N  NH2   . ARG B 1 198 ? 97.213  70.193  91.044  1.00 32.42 ? 198 ARG B NH2   1 
ATOM   3858 N  N     . PHE B 1 199 ? 100.132 63.971  88.415  1.00 30.33 ? 199 PHE B N     1 
ATOM   3859 C  CA    . PHE B 1 199 ? 101.198 64.119  87.432  1.00 30.33 ? 199 PHE B CA    1 
ATOM   3860 C  C     . PHE B 1 199 ? 101.886 62.769  87.313  1.00 30.33 ? 199 PHE B C     1 
ATOM   3861 O  O     . PHE B 1 199 ? 102.592 62.359  88.236  1.00 30.33 ? 199 PHE B O     1 
ATOM   3862 C  CB    . PHE B 1 199 ? 102.191 65.186  87.883  1.00 30.33 ? 199 PHE B CB    1 
ATOM   3863 C  CG    . PHE B 1 199 ? 101.552 66.445  88.337  1.00 30.33 ? 199 PHE B CG    1 
ATOM   3864 C  CD1   . PHE B 1 199 ? 101.049 67.349  87.447  1.00 30.33 ? 199 PHE B CD1   1 
ATOM   3865 C  CD2   . PHE B 1 199 ? 101.438 66.713  89.676  1.00 30.33 ? 199 PHE B CD2   1 
ATOM   3866 C  CE1   . PHE B 1 199 ? 100.454 68.498  87.881  1.00 30.33 ? 199 PHE B CE1   1 
ATOM   3867 C  CE2   . PHE B 1 199 ? 100.838 67.858  90.103  1.00 30.33 ? 199 PHE B CE2   1 
ATOM   3868 C  CZ    . PHE B 1 199 ? 100.353 68.746  89.202  1.00 30.33 ? 199 PHE B CZ    1 
ATOM   3869 N  N     . ASP B 1 200 ? 101.646 62.050  86.216  1.00 34.65 ? 200 ASP B N     1 
ATOM   3870 C  CA    . ASP B 1 200 ? 102.249 60.731  86.056  1.00 34.65 ? 200 ASP B CA    1 
ATOM   3871 C  C     . ASP B 1 200 ? 103.720 60.782  85.664  1.00 34.65 ? 200 ASP B C     1 
ATOM   3872 O  O     . ASP B 1 200 ? 104.380 59.743  85.682  1.00 34.65 ? 200 ASP B O     1 
ATOM   3873 C  CB    . ASP B 1 200 ? 101.473 59.896  85.032  1.00 34.65 ? 200 ASP B CB    1 
ATOM   3874 C  CG    . ASP B 1 200 ? 101.460 60.517  83.659  1.00 34.65 ? 200 ASP B CG    1 
ATOM   3875 O  OD1   . ASP B 1 200 ? 100.906 61.627  83.521  1.00 34.65 ? 200 ASP B OD1   1 
ATOM   3876 O  OD2   . ASP B 1 200 ? 102.006 59.906  82.717  1.00 34.65 ? 200 ASP B OD2   1 
ATOM   3877 N  N     . SER B 1 201 ? 104.253 61.955  85.330  1.00 30.31 ? 201 SER B N     1 
ATOM   3878 C  CA    . SER B 1 201 ? 105.664 62.087  85.000  1.00 30.31 ? 201 SER B CA    1 
ATOM   3879 C  C     . SER B 1 201 ? 106.190 63.434  85.470  1.00 30.31 ? 201 SER B C     1 
ATOM   3880 O  O     . SER B 1 201 ? 105.442 64.403  85.592  1.00 30.31 ? 201 SER B O     1 
ATOM   3881 C  CB    . SER B 1 201 ? 105.879 61.937  83.498  1.00 30.31 ? 201 SER B CB    1 
ATOM   3882 O  OG    . SER B 1 201 ? 105.702 63.187  82.865  1.00 30.31 ? 201 SER B OG    1 
ATOM   3883 N  N     . VAL B 1 202 ? 107.506 63.501  85.675  1.00 27.25 ? 202 VAL B N     1 
ATOM   3884 C  CA    . VAL B 1 202 ? 108.135 64.756  86.067  1.00 27.25 ? 202 VAL B CA    1 
ATOM   3885 C  C     . VAL B 1 202 ? 107.886 65.820  85.014  1.00 27.25 ? 202 VAL B C     1 
ATOM   3886 O  O     . VAL B 1 202 ? 107.759 67.008  85.330  1.00 27.25 ? 202 VAL B O     1 
ATOM   3887 C  CB    . VAL B 1 202 ? 109.643 64.548  86.305  1.00 27.25 ? 202 VAL B CB    1 
ATOM   3888 C  CG1   . VAL B 1 202 ? 110.311 65.858  86.615  1.00 27.25 ? 202 VAL B CG1   1 
ATOM   3889 C  CG2   . VAL B 1 202 ? 109.880 63.584  87.419  1.00 27.25 ? 202 VAL B CG2   1 
ATOM   3890 N  N     . SER B 1 203 ? 107.821 65.416  83.749  1.00 25.64 ? 203 SER B N     1 
ATOM   3891 C  CA    . SER B 1 203 ? 107.591 66.363  82.665  1.00 25.64 ? 203 SER B CA    1 
ATOM   3892 C  C     . SER B 1 203 ? 106.195 66.963  82.727  1.00 25.64 ? 203 SER B C     1 
ATOM   3893 O  O     . SER B 1 203 ? 106.013 68.133  82.377  1.00 25.64 ? 203 SER B O     1 
ATOM   3894 C  CB    . SER B 1 203 ? 107.831 65.668  81.338  1.00 25.64 ? 203 SER B CB    1 
ATOM   3895 O  OG    . SER B 1 203 ? 109.134 65.125  81.321  1.00 25.64 ? 203 SER B OG    1 
ATOM   3896 N  N     . LYS B 1 204 ? 105.214 66.198  83.225  1.00 26.34 ? 204 LYS B N     1 
ATOM   3897 C  CA    . LYS B 1 204 ? 103.877 66.742  83.457  1.00 26.34 ? 204 LYS B CA    1 
ATOM   3898 C  C     . LYS B 1 204 ? 103.904 67.844  84.502  1.00 26.34 ? 204 LYS B C     1 
ATOM   3899 O  O     . LYS B 1 204 ? 103.270 68.887  84.324  1.00 26.34 ? 204 LYS B O     1 
ATOM   3900 C  CB    . LYS B 1 204 ? 102.926 65.645  83.924  1.00 26.34 ? 204 LYS B CB    1 
ATOM   3901 C  CG    . LYS B 1 204 ? 102.558 64.578  82.942  1.00 26.34 ? 204 LYS B CG    1 
ATOM   3902 C  CD    . LYS B 1 204 ? 101.997 65.157  81.670  1.00 26.34 ? 204 LYS B CD    1 
ATOM   3903 C  CE    . LYS B 1 204 ? 101.615 64.056  80.712  1.00 26.34 ? 204 LYS B CE    1 
ATOM   3904 N  NZ    . LYS B 1 204 ? 100.496 63.207  81.210  1.00 26.34 ? 204 LYS B NZ    1 
ATOM   3905 N  N     . LEU B 1 205 ? 104.633 67.630  85.597  1.00 23.51 ? 205 LEU B N     1 
ATOM   3906 C  CA    . LEU B 1 205 ? 104.747 68.652  86.628  1.00 23.51 ? 205 LEU B CA    1 
ATOM   3907 C  C     . LEU B 1 205 ? 105.511 69.860  86.111  1.00 23.51 ? 205 LEU B C     1 
ATOM   3908 O  O     . LEU B 1 205 ? 105.158 70.990  86.433  1.00 23.51 ? 205 LEU B O     1 
ATOM   3909 C  CB    . LEU B 1 205 ? 105.378 68.074  87.894  1.00 23.51 ? 205 LEU B CB    1 
ATOM   3910 C  CG    . LEU B 1 205 ? 105.655 69.028  89.065  1.00 23.51 ? 205 LEU B CG    1 
ATOM   3911 C  CD1   . LEU B 1 205 ? 104.394 69.671  89.565  1.00 23.51 ? 205 LEU B CD1   1 
ATOM   3912 C  CD2   . LEU B 1 205 ? 106.316 68.296  90.198  1.00 23.51 ? 205 LEU B CD2   1 
ATOM   3913 N  N     . TRP B 1 206 ? 106.589 69.658  85.352  1.00 22.16 ? 206 TRP B N     1 
ATOM   3914 C  CA    . TRP B 1 206 ? 107.286 70.815  84.792  1.00 22.16 ? 206 TRP B CA    1 
ATOM   3915 C  C     . TRP B 1 206 ? 106.360 71.621  83.891  1.00 22.16 ? 206 TRP B C     1 
ATOM   3916 O  O     . TRP B 1 206 ? 106.372 72.854  83.920  1.00 22.16 ? 206 TRP B O     1 
ATOM   3917 C  CB    . TRP B 1 206 ? 108.537 70.405  84.000  1.00 22.16 ? 206 TRP B CB    1 
ATOM   3918 C  CG    . TRP B 1 206 ? 109.695 69.836  84.793  1.00 22.16 ? 206 TRP B CG    1 
ATOM   3919 C  CD1   . TRP B 1 206 ? 109.923 69.967  86.123  1.00 22.16 ? 206 TRP B CD1   1 
ATOM   3920 C  CD2   . TRP B 1 206 ? 110.796 69.084  84.274  1.00 22.16 ? 206 TRP B CD2   1 
ATOM   3921 N  NE1   . TRP B 1 206 ? 111.068 69.311  86.478  1.00 22.16 ? 206 TRP B NE1   1 
ATOM   3922 C  CE2   . TRP B 1 206 ? 111.631 68.768  85.357  1.00 22.16 ? 206 TRP B CE2   1 
ATOM   3923 C  CE3   . TRP B 1 206 ? 111.145 68.631  83.003  1.00 22.16 ? 206 TRP B CE3   1 
ATOM   3924 C  CZ2   . TRP B 1 206 ? 112.794 68.024  85.208  1.00 22.16 ? 206 TRP B CZ2   1 
ATOM   3925 C  CZ3   . TRP B 1 206 ? 112.299 67.892  82.859  1.00 22.16 ? 206 TRP B CZ3   1 
ATOM   3926 C  CH2   . TRP B 1 206 ? 113.110 67.600  83.953  1.00 22.16 ? 206 TRP B CH2   1 
ATOM   3927 N  N     . ALA B 1 207 ? 105.562 70.938  83.066  1.00 20.92 ? 207 ALA B N     1 
ATOM   3928 C  CA    . ALA B 1 207 ? 104.611 71.620  82.194  1.00 20.92 ? 207 ALA B CA    1 
ATOM   3929 C  C     . ALA B 1 207 ? 103.549 72.381  82.979  1.00 20.92 ? 207 ALA B C     1 
ATOM   3930 O  O     . ALA B 1 207 ? 103.278 73.551  82.702  1.00 20.92 ? 207 ALA B O     1 
ATOM   3931 C  CB    . ALA B 1 207 ? 103.966 70.606  81.270  1.00 20.92 ? 207 ALA B CB    1 
ATOM   3932 N  N     . TYR B 1 208 ? 102.934 71.720  83.957  1.00 21.23 ? 208 TYR B N     1 
ATOM   3933 C  CA    . TYR B 1 208 ? 101.949 72.359  84.819  1.00 21.23 ? 208 TYR B CA    1 
ATOM   3934 C  C     . TYR B 1 208 ? 102.534 73.521  85.600  1.00 21.23 ? 208 TYR B C     1 
ATOM   3935 O  O     . TYR B 1 208 ? 101.878 74.547  85.774  1.00 21.23 ? 208 TYR B O     1 
ATOM   3936 C  CB    . TYR B 1 208 ? 101.363 71.308  85.749  1.00 21.23 ? 208 TYR B CB    1 
ATOM   3937 C  CG    . TYR B 1 208 ? 100.326 71.785  86.735  1.00 21.23 ? 208 TYR B CG    1 
ATOM   3938 C  CD1   . TYR B 1 208 ? 99.044  72.108  86.327  1.00 21.23 ? 208 TYR B CD1   1 
ATOM   3939 C  CD2   . TYR B 1 208 ? 100.586 71.769  88.092  1.00 21.23 ? 208 TYR B CD2   1 
ATOM   3940 C  CE1   . TYR B 1 208 ? 98.090  72.513  87.237  1.00 21.23 ? 208 TYR B CE1   1 
ATOM   3941 C  CE2   . TYR B 1 208 ? 99.633  72.130  89.004  1.00 21.23 ? 208 TYR B CE2   1 
ATOM   3942 C  CZ    . TYR B 1 208 ? 98.390  72.513  88.575  1.00 21.23 ? 208 TYR B CZ    1 
ATOM   3943 O  OH    . TYR B 1 208 ? 97.442  72.879  89.488  1.00 21.23 ? 208 TYR B OH    1 
ATOM   3944 N  N     . ALA B 1 209 ? 103.777 73.395  86.038  1.00 18.40 ? 209 ALA B N     1 
ATOM   3945 C  CA    . ALA B 1 209 ? 104.444 74.431  86.802  1.00 18.40 ? 209 ALA B CA    1 
ATOM   3946 C  C     . ALA B 1 209 ? 104.956 75.573  85.945  1.00 18.40 ? 209 ALA B C     1 
ATOM   3947 O  O     . ALA B 1 209 ? 105.165 76.664  86.472  1.00 18.40 ? 209 ALA B O     1 
ATOM   3948 C  CB    . ALA B 1 209 ? 105.594 73.817  87.596  1.00 18.40 ? 209 ALA B CB    1 
ATOM   3949 N  N     . GLY B 1 210 ? 105.168 75.356  84.653  1.00 19.17 ? 210 GLY B N     1 
ATOM   3950 C  CA    . GLY B 1 210 ? 105.620 76.404  83.766  1.00 19.17 ? 210 GLY B CA    1 
ATOM   3951 C  C     . GLY B 1 210 ? 107.065 76.341  83.348  1.00 19.17 ? 210 GLY B C     1 
ATOM   3952 O  O     . GLY B 1 210 ? 107.619 77.373  82.967  1.00 19.17 ? 210 GLY B O     1 
ATOM   3953 N  N     . TYR B 1 211 ? 107.688 75.169  83.426  1.00 21.11 ? 211 TYR B N     1 
ATOM   3954 C  CA    . TYR B 1 211 ? 109.090 74.948  83.109  1.00 21.11 ? 211 TYR B CA    1 
ATOM   3955 C  C     . TYR B 1 211 ? 109.327 74.120  81.847  1.00 21.11 ? 211 TYR B C     1 
ATOM   3956 O  O     . TYR B 1 211 ? 110.477 73.796  81.552  1.00 21.11 ? 211 TYR B O     1 
ATOM   3957 C  CB    . TYR B 1 211 ? 109.773 74.276  84.297  1.00 21.11 ? 211 TYR B CB    1 
ATOM   3958 C  CG    . TYR B 1 211 ? 110.035 75.204  85.458  1.00 21.11 ? 211 TYR B CG    1 
ATOM   3959 C  CD1   . TYR B 1 211 ? 110.688 76.408  85.268  1.00 21.11 ? 211 TYR B CD1   1 
ATOM   3960 C  CD2   . TYR B 1 211 ? 109.670 74.857  86.743  1.00 21.11 ? 211 TYR B CD2   1 
ATOM   3961 C  CE1   . TYR B 1 211 ? 110.943 77.246  86.308  1.00 21.11 ? 211 TYR B CE1   1 
ATOM   3962 C  CE2   . TYR B 1 211 ? 109.925 75.690  87.795  1.00 21.11 ? 211 TYR B CE2   1 
ATOM   3963 C  CZ    . TYR B 1 211 ? 110.563 76.884  87.574  1.00 21.11 ? 211 TYR B CZ    1 
ATOM   3964 O  OH    . TYR B 1 211 ? 110.818 77.731  88.622  1.00 21.11 ? 211 TYR B OH    1 
ATOM   3965 N  N     . SER B 1 212 ? 108.290 73.791  81.083  1.00 25.64 ? 212 SER B N     1 
ATOM   3966 C  CA    . SER B 1 212 ? 108.444 72.959  79.898  1.00 25.64 ? 212 SER B CA    1 
ATOM   3967 C  C     . SER B 1 212 ? 109.106 73.731  78.751  1.00 25.64 ? 212 SER B C     1 
ATOM   3968 O  O     . SER B 1 212 ? 109.217 74.960  78.772  1.00 25.64 ? 212 SER B O     1 
ATOM   3969 C  CB    . SER B 1 212 ? 107.083 72.406  79.490  1.00 25.64 ? 212 SER B CB    1 
ATOM   3970 O  OG    . SER B 1 212 ? 107.171 71.582  78.351  1.00 25.64 ? 212 SER B OG    1 
ATOM   3971 N  N     . VAL B 1 213 ? 109.532 72.986  77.720  1.00 34.62 ? 213 VAL B N     1 
ATOM   3972 C  CA    . VAL B 1 213 ? 110.215 73.545  76.552  1.00 34.62 ? 213 VAL B CA    1 
ATOM   3973 C  C     . VAL B 1 213 ? 109.600 72.987  75.272  1.00 34.62 ? 213 VAL B C     1 
ATOM   3974 O  O     . VAL B 1 213 ? 109.449 71.769  75.138  1.00 34.62 ? 213 VAL B O     1 
ATOM   3975 C  CB    . VAL B 1 213 ? 111.724 73.204  76.571  1.00 34.62 ? 213 VAL B CB    1 
ATOM   3976 C  CG1   . VAL B 1 213 ? 112.482 74.054  75.588  1.00 34.62 ? 213 VAL B CG1   1 
ATOM   3977 C  CG2   . VAL B 1 213 ? 112.325 73.316  77.944  1.00 34.62 ? 213 VAL B CG2   1 
ATOM   3978 N  N     . ASP B 1 214 ? 109.237 73.878  74.339  1.00 44.44 ? 214 ASP B N     1 
ATOM   3979 C  CA    . ASP B 1 214 ? 108.710 73.512  73.023  1.00 44.44 ? 214 ASP B CA    1 
ATOM   3980 C  C     . ASP B 1 214 ? 109.671 74.011  71.953  1.00 44.44 ? 214 ASP B C     1 
ATOM   3981 O  O     . ASP B 1 214 ? 109.792 75.225  71.765  1.00 44.44 ? 214 ASP B O     1 
ATOM   3982 C  CB    . ASP B 1 214 ? 107.343 74.148  72.772  1.00 44.44 ? 214 ASP B CB    1 
ATOM   3983 C  CG    . ASP B 1 214 ? 106.236 73.546  73.603  1.00 44.44 ? 214 ASP B CG    1 
ATOM   3984 O  OD1   . ASP B 1 214 ? 106.357 72.383  74.040  1.00 44.44 ? 214 ASP B OD1   1 
ATOM   3985 O  OD2   . ASP B 1 214 ? 105.235 74.264  73.819  1.00 44.44 ? 214 ASP B OD2   1 
ATOM   3986 N  N     . ASN B 1 215 ? 110.294 73.091  71.208  1.00 44.22 ? 215 ASN B N     1 
ATOM   3987 C  CA    . ASN B 1 215 ? 111.237 73.455  70.139  1.00 44.22 ? 215 ASN B CA    1 
ATOM   3988 C  C     . ASN B 1 215 ? 112.243 74.511  70.594  1.00 44.22 ? 215 ASN B C     1 
ATOM   3989 O  O     . ASN B 1 215 ? 112.630 75.390  69.823  1.00 44.22 ? 215 ASN B O     1 
ATOM   3990 C  CB    . ASN B 1 215 ? 110.531 73.877  68.843  1.00 44.22 ? 215 ASN B CB    1 
ATOM   3991 C  CG    . ASN B 1 215 ? 109.583 72.808  68.320  1.00 44.22 ? 215 ASN B CG    1 
ATOM   3992 O  OD1   . ASN B 1 215 ? 110.013 71.713  67.965  1.00 44.22 ? 215 ASN B OD1   1 
ATOM   3993 N  ND2   . ASN B 1 215 ? 108.298 73.127  68.249  1.00 44.22 ? 215 ASN B ND2   1 
ATOM   3994 N  N     . GLY B 1 216 ? 112.653 74.434  71.857  1.00 40.89 ? 216 GLY B N     1 
ATOM   3995 C  CA    . GLY B 1 216 ? 113.577 75.380  72.451  1.00 40.89 ? 216 GLY B CA    1 
ATOM   3996 C  C     . GLY B 1 216 ? 113.000 76.681  72.968  1.00 40.89 ? 216 GLY B C     1 
ATOM   3997 O  O     . GLY B 1 216 ? 113.771 77.588  73.286  1.00 40.89 ? 216 GLY B O     1 
ATOM   3998 N  N     . LYS B 1 217 ? 111.682 76.810  73.062  1.00 36.91 ? 217 LYS B N     1 
ATOM   3999 C  CA    . LYS B 1 217 ? 111.039 77.998  73.607  1.00 36.91 ? 217 LYS B CA    1 
ATOM   4000 C  C     . LYS B 1 217 ? 110.317 77.673  74.913  1.00 36.91 ? 217 LYS B C     1 
ATOM   4001 O  O     . LYS B 1 217 ? 109.608 76.666  75.009  1.00 36.91 ? 217 LYS B O     1 
ATOM   4002 C  CB    . LYS B 1 217 ? 110.078 78.642  72.608  1.00 36.91 ? 217 LYS B CB    1 
ATOM   4003 C  CG    . LYS B 1 217 ? 110.748 79.101  71.340  1.00 36.91 ? 217 LYS B CG    1 
ATOM   4004 C  CD    . LYS B 1 217 ? 109.764 79.742  70.386  1.00 36.91 ? 217 LYS B CD    1 
ATOM   4005 C  CE    . LYS B 1 217 ? 110.454 80.184  69.093  1.00 36.91 ? 217 LYS B CE    1 
ATOM   4006 N  NZ    . LYS B 1 217 ? 109.499 80.683  68.073  1.00 36.91 ? 217 LYS B NZ    1 
ATOM   4007 N  N     . VAL B 1 218 ? 110.554 78.510  75.926  1.00 26.43 ? 218 VAL B N     1 
ATOM   4008 C  CA    . VAL B 1 218 ? 109.921 78.387  77.232  1.00 26.43 ? 218 VAL B CA    1 
ATOM   4009 C  C     . VAL B 1 218 ? 108.527 79.011  77.212  1.00 26.43 ? 218 VAL B C     1 
ATOM   4010 O  O     . VAL B 1 218 ? 108.193 79.819  76.347  1.00 26.43 ? 218 VAL B O     1 
ATOM   4011 C  CB    . VAL B 1 218 ? 110.800 79.024  78.321  1.00 26.43 ? 218 VAL B CB    1 
ATOM   4012 C  CG1   . VAL B 1 218 ? 112.163 78.390  78.332  1.00 26.43 ? 218 VAL B CG1   1 
ATOM   4013 C  CG2   . VAL B 1 218 ? 110.904 80.529  78.104  1.00 26.43 ? 218 VAL B CG2   1 
ATOM   4014 N  N     . GLN B 1 219 ? 107.707 78.612  78.192  1.00 20.08 ? 219 GLN B N     1 
ATOM   4015 C  CA    . GLN B 1 219 ? 106.362 79.150  78.399  1.00 20.08 ? 219 GLN B CA    1 
ATOM   4016 C  C     . GLN B 1 219 ? 106.426 80.574  78.932  1.00 20.08 ? 219 GLN B C     1 
ATOM   4017 O  O     . GLN B 1 219 ? 106.976 80.804  80.008  1.00 20.08 ? 219 GLN B O     1 
ATOM   4018 C  CB    . GLN B 1 219 ? 105.597 78.265  79.376  1.00 20.08 ? 219 GLN B CB    1 
ATOM   4019 C  CG    . GLN B 1 219 ? 105.226 76.937  78.795  1.00 20.08 ? 219 GLN B CG    1 
ATOM   4020 C  CD    . GLN B 1 219 ? 104.979 75.900  79.831  1.00 20.08 ? 219 GLN B CD    1 
ATOM   4021 O  OE1   . GLN B 1 219 ? 105.834 75.618  80.646  1.00 20.08 ? 219 GLN B OE1   1 
ATOM   4022 N  NE2   . GLN B 1 219 ? 103.829 75.276  79.773  1.00 20.08 ? 219 GLN B NE2   1 
ATOM   4023 N  N     . LYS B 1 220 ? 105.883 81.534  78.191  1.00 22.34 ? 220 LYS B N     1 
ATOM   4024 C  CA    . LYS B 1 220 ? 105.884 82.923  78.617  1.00 22.34 ? 220 LYS B CA    1 
ATOM   4025 C  C     . LYS B 1 220 ? 104.479 83.499  78.547  1.00 22.34 ? 220 LYS B C     1 
ATOM   4026 O  O     . LYS B 1 220 ? 103.713 83.147  77.651  1.00 22.34 ? 220 LYS B O     1 
ATOM   4027 C  CB    . LYS B 1 220 ? 106.826 83.766  77.750  1.00 22.34 ? 220 LYS B CB    1 
ATOM   4028 C  CG    . LYS B 1 220 ? 108.258 83.266  77.779  1.00 22.34 ? 220 LYS B CG    1 
ATOM   4029 C  CD    . LYS B 1 220 ? 109.261 84.264  77.229  1.00 22.34 ? 220 LYS B CD    1 
ATOM   4030 C  CE    . LYS B 1 220 ? 109.482 85.413  78.203  1.00 22.34 ? 220 LYS B CE    1 
ATOM   4031 N  NZ    . LYS B 1 220 ? 110.588 86.325  77.803  1.00 22.34 ? 220 LYS B NZ    1 
ATOM   4032 N  N     . ARG B 1 221 ? 104.129 84.359  79.502  1.00 23.02 ? 221 ARG B N     1 
ATOM   4033 C  CA    . ARG B 1 221 ? 102.828 85.010  79.469  1.00 23.02 ? 221 ARG B CA    1 
ATOM   4034 C  C     . ARG B 1 221 ? 102.689 85.763  78.157  1.00 23.02 ? 221 ARG B C     1 
ATOM   4035 O  O     . ARG B 1 221 ? 103.667 86.252  77.600  1.00 23.02 ? 221 ARG B O     1 
ATOM   4036 C  CB    . ARG B 1 221 ? 102.653 85.966  80.649  1.00 23.02 ? 221 ARG B CB    1 
ATOM   4037 C  CG    . ARG B 1 221 ? 102.604 85.315  82.021  1.00 23.02 ? 221 ARG B CG    1 
ATOM   4038 C  CD    . ARG B 1 221 ? 102.356 86.340  83.147  1.00 23.02 ? 221 ARG B CD    1 
ATOM   4039 N  NE    . ARG B 1 221 ? 103.466 87.274  83.317  1.00 23.02 ? 221 ARG B NE    1 
ATOM   4040 C  CZ    . ARG B 1 221 ? 103.418 88.420  83.986  1.00 23.02 ? 221 ARG B CZ    1 
ATOM   4041 N  NH1   . ARG B 1 221 ? 102.299 88.869  84.519  1.00 23.02 ? 221 ARG B NH1   1 
ATOM   4042 N  NH2   . ARG B 1 221 ? 104.524 89.141  84.118  1.00 23.02 ? 221 ARG B NH2   1 
ATOM   4043 N  N     . LYS B 1 222 ? 101.460 85.864  77.664  1.00 30.19 ? 222 LYS B N     1 
ATOM   4044 C  CA    . LYS B 1 222 ? 101.235 86.463  76.354  1.00 30.19 ? 222 LYS B CA    1 
ATOM   4045 C  C     . LYS B 1 222 ? 99.818  87.010  76.259  1.00 30.19 ? 222 LYS B C     1 
ATOM   4046 O  O     . LYS B 1 222 ? 98.861  86.238  76.335  1.00 30.19 ? 222 LYS B O     1 
ATOM   4047 C  CB    . LYS B 1 222 ? 101.489 85.411  75.281  1.00 30.19 ? 222 LYS B CB    1 
ATOM   4048 C  CG    . LYS B 1 222 ? 101.275 85.857  73.864  1.00 30.19 ? 222 LYS B CG    1 
ATOM   4049 C  CD    . LYS B 1 222 ? 101.670 84.745  72.921  1.00 30.19 ? 222 LYS B CD    1 
ATOM   4050 C  CE    . LYS B 1 222 ? 101.448 85.135  71.479  1.00 30.19 ? 222 LYS B CE    1 
ATOM   4051 N  NZ    . LYS B 1 222 ? 101.964 84.104  70.550  1.00 30.19 ? 222 LYS B NZ    1 
ATOM   4052 N  N     . LYS B 1 223 ? 99.690  88.331  76.145  1.00 34.28 ? 223 LYS B N     1 
ATOM   4053 C  CA    . LYS B 1 223 ? 98.390  88.987  76.018  1.00 34.28 ? 223 LYS B CA    1 
ATOM   4054 C  C     . LYS B 1 223 ? 97.540  88.322  74.945  1.00 34.28 ? 223 LYS B C     1 
ATOM   4055 O  O     . LYS B 1 223 ? 98.017  88.048  73.842  1.00 34.28 ? 223 LYS B O     1 
ATOM   4056 C  CB    . LYS B 1 223 ? 98.560  90.458  75.653  1.00 34.28 ? 223 LYS B CB    1 
ATOM   4057 C  CG    . LYS B 1 223 ? 98.930  91.427  76.765  1.00 34.28 ? 223 LYS B CG    1 
ATOM   4058 C  CD    . LYS B 1 223 ? 99.460  92.721  76.125  1.00 34.28 ? 223 LYS B CD    1 
ATOM   4059 C  CE    . LYS B 1 223 ? 99.801  93.808  77.146  1.00 34.28 ? 223 LYS B CE    1 
ATOM   4060 N  NZ    . LYS B 1 223 ? 100.460 95.009  76.537  1.00 34.28 ? 223 LYS B NZ    1 
ATOM   4061 N  N     . GLY B 1 224 ? 96.296  88.010  75.281  1.00 31.00 ? 224 GLY B N     1 
ATOM   4062 C  CA    . GLY B 1 224 ? 95.410  87.428  74.306  1.00 31.00 ? 224 GLY B CA    1 
ATOM   4063 C  C     . GLY B 1 224 ? 95.497  85.933  74.177  1.00 31.00 ? 224 GLY B C     1 
ATOM   4064 O  O     . GLY B 1 224 ? 94.742  85.348  73.392  1.00 31.00 ? 224 GLY B O     1 
ATOM   4065 N  N     . VAL B 1 225 ? 96.403  85.293  74.901  1.00 28.51 ? 225 VAL B N     1 
ATOM   4066 C  CA    . VAL B 1 225 ? 96.557  83.853  74.848  1.00 28.51 ? 225 VAL B CA    1 
ATOM   4067 C  C     . VAL B 1 225 ? 96.434  83.339  76.267  1.00 28.51 ? 225 VAL B C     1 
ATOM   4068 O  O     . VAL B 1 225 ? 97.193  83.752  77.148  1.00 28.51 ? 225 VAL B O     1 
ATOM   4069 C  CB    . VAL B 1 225 ? 97.899  83.439  74.230  1.00 28.51 ? 225 VAL B CB    1 
ATOM   4070 C  CG1   . VAL B 1 225 ? 98.024  81.941  74.210  1.00 28.51 ? 225 VAL B CG1   1 
ATOM   4071 C  CG2   . VAL B 1 225 ? 98.016  83.988  72.834  1.00 28.51 ? 225 VAL B CG2   1 
ATOM   4072 N  N     . ALA B 1 226 ? 95.457  82.477  76.496  1.00 24.92 ? 226 ALA B N     1 
ATOM   4073 C  CA    . ALA B 1 226 ? 95.286  81.882  77.803  1.00 24.92 ? 226 ALA B CA    1 
ATOM   4074 C  C     . ALA B 1 226 ? 96.482  81.013  78.121  1.00 24.92 ? 226 ALA B C     1 
ATOM   4075 O  O     . ALA B 1 226 ? 96.904  80.186  77.313  1.00 24.92 ? 226 ALA B O     1 
ATOM   4076 C  CB    . ALA B 1 226 ? 94.004  81.061  77.852  1.00 24.92 ? 226 ALA B CB    1 
ATOM   4077 N  N     . SER B 1 227 ? 97.009  81.185  79.316  1.00 20.51 ? 227 SER B N     1 
ATOM   4078 C  CA    . SER B 1 227 ? 98.118  80.382  79.760  1.00 20.51 ? 227 SER B CA    1 
ATOM   4079 C  C     . SER B 1 227 ? 97.635  78.961  80.037  1.00 20.51 ? 227 SER B C     1 
ATOM   4080 O  O     . SER B 1 227 ? 96.442  78.676  80.039  1.00 20.51 ? 227 SER B O     1 
ATOM   4081 C  CB    . SER B 1 227 ? 98.717  81.035  80.992  1.00 20.51 ? 227 SER B CB    1 
ATOM   4082 O  OG    . SER B 1 227 ? 99.659  80.219  81.618  1.00 20.51 ? 227 SER B OG    1 
ATOM   4083 N  N     . ASN B 1 228 ? 98.571  78.044  80.208  1.00 18.55 ? 228 ASN B N     1 
ATOM   4084 C  CA    . ASN B 1 228 ? 98.190  76.670  80.498  1.00 18.55 ? 228 ASN B CA    1 
ATOM   4085 C  C     . ASN B 1 228 ? 99.103  76.053  81.550  1.00 18.55 ? 228 ASN B C     1 
ATOM   4086 O  O     . ASN B 1 228 ? 99.296  74.835  81.582  1.00 18.55 ? 228 ASN B O     1 
ATOM   4087 C  CB    . ASN B 1 228 ? 98.100  75.841  79.208  1.00 18.55 ? 228 ASN B CB    1 
ATOM   4088 C  CG    . ASN B 1 228 ? 99.436  75.533  78.590  1.00 18.55 ? 228 ASN B CG    1 
ATOM   4089 O  OD1   . ASN B 1 228 ? 100.366 76.324  78.663  1.00 18.55 ? 228 ASN B OD1   1 
ATOM   4090 N  ND2   . ASN B 1 228 ? 99.520  74.395  77.925  1.00 18.55 ? 228 ASN B ND2   1 
ATOM   4091 N  N     . TRP B 1 229 ? 99.630  76.887  82.442  1.00 15.28 ? 229 TRP B N     1 
ATOM   4092 C  CA    . TRP B 1 229 ? 100.454 76.463  83.559  1.00 15.28 ? 229 TRP B CA    1 
ATOM   4093 C  C     . TRP B 1 229 ? 100.043 77.281  84.775  1.00 15.28 ? 229 TRP B C     1 
ATOM   4094 O  O     . TRP B 1 229 ? 99.471  78.365  84.647  1.00 15.28 ? 229 TRP B O     1 
ATOM   4095 C  CB    . TRP B 1 229 ? 101.955 76.632  83.274  1.00 15.28 ? 229 TRP B CB    1 
ATOM   4096 C  CG    . TRP B 1 229 ? 102.424 78.044  83.114  1.00 15.28 ? 229 TRP B CG    1 
ATOM   4097 C  CD1   . TRP B 1 229 ? 103.023 78.803  84.058  1.00 15.28 ? 229 TRP B CD1   1 
ATOM   4098 C  CD2   . TRP B 1 229 ? 102.403 78.833  81.927  1.00 15.28 ? 229 TRP B CD2   1 
ATOM   4099 N  NE1   . TRP B 1 229 ? 103.327 80.028  83.562  1.00 15.28 ? 229 TRP B NE1   1 
ATOM   4100 C  CE2   . TRP B 1 229 ? 102.959 80.075  82.248  1.00 15.28 ? 229 TRP B CE2   1 
ATOM   4101 C  CE3   . TRP B 1 229 ? 101.942 78.622  80.631  1.00 15.28 ? 229 TRP B CE3   1 
ATOM   4102 C  CZ2   . TRP B 1 229 ? 103.072 81.101  81.321  1.00 15.28 ? 229 TRP B CZ2   1 
ATOM   4103 C  CZ3   . TRP B 1 229 ? 102.055 79.627  79.720  1.00 15.28 ? 229 TRP B CZ3   1 
ATOM   4104 C  CH2   . TRP B 1 229 ? 102.611 80.857  80.062  1.00 15.28 ? 229 TRP B CH2   1 
ATOM   4105 N  N     . LYS B 1 230 ? 100.242 76.708  85.953  1.00 15.38 ? 230 LYS B N     1 
ATOM   4106 C  CA    . LYS B 1 230 ? 99.987  77.399  87.214  1.00 15.38 ? 230 LYS B CA    1 
ATOM   4107 C  C     . LYS B 1 230 ? 101.222 78.237  87.551  1.00 15.38 ? 230 LYS B C     1 
ATOM   4108 O  O     . LYS B 1 230 ? 102.167 77.762  88.156  1.00 15.38 ? 230 LYS B O     1 
ATOM   4109 C  CB    . LYS B 1 230 ? 99.630  76.383  88.290  1.00 15.38 ? 230 LYS B CB    1 
ATOM   4110 C  CG    . LYS B 1 230 ? 99.186  76.940  89.600  1.00 15.38 ? 230 LYS B CG    1 
ATOM   4111 C  CD    . LYS B 1 230 ? 98.641  75.833  90.478  1.00 15.38 ? 230 LYS B CD    1 
ATOM   4112 C  CE    . LYS B 1 230 ? 98.103  76.401  91.754  1.00 15.38 ? 230 LYS B CE    1 
ATOM   4113 N  NZ    . LYS B 1 230 ? 97.375  75.442  92.577  1.00 15.38 ? 230 LYS B NZ    1 
ATOM   4114 N  N     . ASN B 1 231 ? 101.246 79.491  87.117  1.00 14.71 ? 231 ASN B N     1 
ATOM   4115 C  CA    . ASN B 1 231 ? 102.438 80.311  87.313  1.00 14.71 ? 231 ASN B CA    1 
ATOM   4116 C  C     . ASN B 1 231 ? 102.805 80.542  88.771  1.00 14.71 ? 231 ASN B C     1 
ATOM   4117 O  O     . ASN B 1 231 ? 103.961 80.865  89.061  1.00 14.71 ? 231 ASN B O     1 
ATOM   4118 C  CB    . ASN B 1 231 ? 102.257 81.647  86.603  1.00 14.71 ? 231 ASN B CB    1 
ATOM   4119 C  CG    . ASN B 1 231 ? 103.539 82.415  86.467  1.00 14.71 ? 231 ASN B CG    1 
ATOM   4120 O  OD1   . ASN B 1 231 ? 104.548 81.881  86.057  1.00 14.71 ? 231 ASN B OD1   1 
ATOM   4121 N  ND2   . ASN B 1 231 ? 103.474 83.704  86.711  1.00 14.71 ? 231 ASN B ND2   1 
ATOM   4122 N  N     . LYS B 1 232 ? 101.862 80.416  89.694  1.00 15.25 ? 232 LYS B N     1 
ATOM   4123 C  CA    . LYS B 1 232 ? 102.205 80.579  91.096  1.00 15.25 ? 232 LYS B CA    1 
ATOM   4124 C  C     . LYS B 1 232 ? 103.205 79.543  91.591  1.00 15.25 ? 232 LYS B C     1 
ATOM   4125 O  O     . LYS B 1 232 ? 104.027 79.860  92.449  1.00 15.25 ? 232 LYS B O     1 
ATOM   4126 C  CB    . LYS B 1 232 ? 100.940 80.656  91.940  1.00 15.25 ? 232 LYS B CB    1 
ATOM   4127 C  CG    . LYS B 1 232 ? 100.199 81.919  91.582  1.00 15.25 ? 232 LYS B CG    1 
ATOM   4128 C  CD    . LYS B 1 232 ? 99.162  82.388  92.576  1.00 15.25 ? 232 LYS B CD    1 
ATOM   4129 C  CE    . LYS B 1 232 ? 98.061  81.421  92.797  1.00 15.25 ? 232 LYS B CE    1 
ATOM   4130 N  NZ    . LYS B 1 232 ? 97.013  82.045  93.642  1.00 15.25 ? 232 LYS B NZ    1 
ATOM   4131 N  N     . ILE B 1 233 ? 103.187 78.320  91.069  1.00 16.21 ? 233 ILE B N     1 
ATOM   4132 C  CA    . ILE B 1 233 ? 104.219 77.383  91.509  1.00 16.21 ? 233 ILE B CA    1 
ATOM   4133 C  C     . ILE B 1 233 ? 105.591 77.757  90.943  1.00 16.21 ? 233 ILE B C     1 
ATOM   4134 O  O     . ILE B 1 233 ? 106.605 77.566  91.612  1.00 16.21 ? 233 ILE B O     1 
ATOM   4135 C  CB    . ILE B 1 233 ? 103.827 75.923  91.228  1.00 16.21 ? 233 ILE B CB    1 
ATOM   4136 C  CG1   . ILE B 1 233 ? 105.008 74.994  91.475  1.00 16.21 ? 233 ILE B CG1   1 
ATOM   4137 C  CG2   . ILE B 1 233 ? 103.324 75.746  89.879  1.00 16.21 ? 233 ILE B CG2   1 
ATOM   4138 C  CD1   . ILE B 1 233 ? 105.379 74.878  92.923  1.00 16.21 ? 233 ILE B CD1   1 
ATOM   4139 N  N     . ARG B 1 234 ? 105.663 78.339  89.750  1.00 15.72 ? 234 ARG B N     1 
ATOM   4140 C  CA    . ARG B 1 234 ? 106.959 78.795  89.248  1.00 15.72 ? 234 ARG B CA    1 
ATOM   4141 C  C     . ARG B 1 234 ? 107.474 79.995  90.051  1.00 15.72 ? 234 ARG B C     1 
ATOM   4142 O  O     . ARG B 1 234 ? 108.672 80.074  90.365  1.00 15.72 ? 234 ARG B O     1 
ATOM   4143 C  CB    . ARG B 1 234 ? 106.859 79.097  87.747  1.00 15.72 ? 234 ARG B CB    1 
ATOM   4144 C  CG    . ARG B 1 234 ? 108.142 79.560  87.063  1.00 15.72 ? 234 ARG B CG    1 
ATOM   4145 C  CD    . ARG B 1 234 ? 107.991 79.615  85.552  1.00 15.72 ? 234 ARG B CD    1 
ATOM   4146 N  NE    . ARG B 1 234 ? 107.183 80.737  85.096  1.00 15.72 ? 234 ARG B NE    1 
ATOM   4147 C  CZ    . ARG B 1 234 ? 106.959 81.048  83.827  1.00 15.72 ? 234 ARG B CZ    1 
ATOM   4148 N  NH1   . ARG B 1 234 ? 107.305 80.241  82.846  1.00 15.72 ? 234 ARG B NH1   1 
ATOM   4149 N  NH2   . ARG B 1 234 ? 106.316 82.170  83.542  1.00 15.72 ? 234 ARG B NH2   1 
ATOM   4150 N  N     . THR B 1 235 ? 106.578 80.894  90.468  1.00 14.74 ? 235 THR B N     1 
ATOM   4151 C  CA    . THR B 1 235 ? 106.998 81.999  91.331  1.00 14.74 ? 235 THR B CA    1 
ATOM   4152 C  C     . THR B 1 235 ? 107.447 81.501  92.701  1.00 14.74 ? 235 THR B C     1 
ATOM   4153 O  O     . THR B 1 235 ? 108.388 82.041  93.285  1.00 14.74 ? 235 THR B O     1 
ATOM   4154 C  CB    . THR B 1 235 ? 105.874 83.007  91.491  1.00 14.74 ? 235 THR B CB    1 
ATOM   4155 O  OG1   . THR B 1 235 ? 105.715 83.733  90.275  1.00 14.74 ? 235 THR B OG1   1 
ATOM   4156 C  CG2   . THR B 1 235 ? 106.189 83.966  92.582  1.00 14.74 ? 235 THR B CG2   1 
ATOM   4157 N  N     . HIS B 1 236 ? 106.782 80.491  93.241  1.00 17.09 ? 236 HIS B N     1 
ATOM   4158 C  CA    . HIS B 1 236 ? 107.189 79.955  94.532  1.00 17.09 ? 236 HIS B CA    1 
ATOM   4159 C  C     . HIS B 1 236 ? 108.546 79.268  94.434  1.00 17.09 ? 236 HIS B C     1 
ATOM   4160 O  O     . HIS B 1 236 ? 109.412 79.432  95.308  1.00 17.09 ? 236 HIS B O     1 
ATOM   4161 C  CB    . HIS B 1 236 ? 106.112 79.003  95.035  1.00 17.09 ? 236 HIS B CB    1 
ATOM   4162 C  CG    . HIS B 1 236 ? 106.272 78.620  96.461  1.00 17.09 ? 236 HIS B CG    1 
ATOM   4163 N  ND1   . HIS B 1 236 ? 106.168 79.527  97.489  1.00 17.09 ? 236 HIS B ND1   1 
ATOM   4164 C  CD2   . HIS B 1 236 ? 106.493 77.420  97.037  1.00 17.09 ? 236 HIS B CD2   1 
ATOM   4165 C  CE1   . HIS B 1 236 ? 106.359 78.906  98.636  1.00 17.09 ? 236 HIS B CE1   1 
ATOM   4166 N  NE2   . HIS B 1 236 ? 106.548 77.626  98.390  1.00 17.09 ? 236 HIS B NE2   1 
ATOM   4167 N  N     . CYS B 1 237 ? 108.729 78.451  93.394  1.00 16.72 ? 237 CYS B N     1 
ATOM   4168 C  CA    . CYS B 1 237 ? 109.996 77.768  93.166  1.00 16.72 ? 237 CYS B CA    1 
ATOM   4169 C  C     . CYS B 1 237 ? 111.148 78.755  93.066  1.00 16.72 ? 237 CYS B C     1 
ATOM   4170 O  O     . CYS B 1 237 ? 112.273 78.449  93.481  1.00 16.72 ? 237 CYS B O     1 
ATOM   4171 C  CB    . CYS B 1 237 ? 109.901 76.905  91.920  1.00 16.72 ? 237 CYS B CB    1 
ATOM   4172 S  SG    . CYS B 1 237 ? 109.053 75.374  92.198  1.00 16.72 ? 237 CYS B SG    1 
ATOM   4173 N  N     . TYR B 1 238 ? 110.903 79.927  92.486  1.00 15.19 ? 238 TYR B N     1 
ATOM   4174 C  CA    . TYR B 1 238 ? 111.946 80.945  92.464  1.00 15.19 ? 238 TYR B CA    1 
ATOM   4175 C  C     . TYR B 1 238 ? 112.463 81.256  93.863  1.00 15.19 ? 238 TYR B C     1 
ATOM   4176 O  O     . TYR B 1 238 ? 113.673 81.380  94.072  1.00 15.19 ? 238 TYR B O     1 
ATOM   4177 C  CB    . TYR B 1 238 ? 111.408 82.210  91.807  1.00 15.19 ? 238 TYR B CB    1 
ATOM   4178 C  CG    . TYR B 1 238 ? 112.380 83.353  91.723  1.00 15.19 ? 238 TYR B CG    1 
ATOM   4179 C  CD1   . TYR B 1 238 ? 113.276 83.468  90.672  1.00 15.19 ? 238 TYR B CD1   1 
ATOM   4180 C  CD2   . TYR B 1 238 ? 112.366 84.348  92.680  1.00 15.19 ? 238 TYR B CD2   1 
ATOM   4181 C  CE1   . TYR B 1 238 ? 114.162 84.511  90.606  1.00 15.19 ? 238 TYR B CE1   1 
ATOM   4182 C  CE2   . TYR B 1 238 ? 113.235 85.404  92.617  1.00 15.19 ? 238 TYR B CE2   1 
ATOM   4183 C  CZ    . TYR B 1 238 ? 114.130 85.484  91.580  1.00 15.19 ? 238 TYR B CZ    1 
ATOM   4184 O  OH    . TYR B 1 238 ? 114.982 86.559  91.523  1.00 15.19 ? 238 TYR B OH    1 
ATOM   4185 N  N     . ASN B 1 239 ? 111.568 81.350  94.842  1.00 13.46 ? 239 ASN B N     1 
ATOM   4186 C  CA    . ASN B 1 239 ? 111.967 81.621  96.218  1.00 13.46 ? 239 ASN B CA    1 
ATOM   4187 C  C     . ASN B 1 239 ? 112.618 80.422  96.871  1.00 13.46 ? 239 ASN B C     1 
ATOM   4188 O  O     . ASN B 1 239 ? 113.492 80.584  97.723  1.00 13.46 ? 239 ASN B O     1 
ATOM   4189 C  CB    . ASN B 1 239 ? 110.769 82.089  97.016  1.00 13.46 ? 239 ASN B CB    1 
ATOM   4190 C  CG    . ASN B 1 239 ? 110.292 83.398  96.559  1.00 13.46 ? 239 ASN B CG    1 
ATOM   4191 O  OD1   . ASN B 1 239 ? 111.081 84.275  96.289  1.00 13.46 ? 239 ASN B OD1   1 
ATOM   4192 N  ND2   . ASN B 1 239 ? 108.994 83.555  96.459  1.00 13.46 ? 239 ASN B ND2   1 
ATOM   4193 N  N     . ILE B 1 240 ? 112.219 79.218  96.492  1.00 16.23 ? 240 ILE B N     1 
ATOM   4194 C  CA    . ILE B 1 240 ? 112.880 78.031  97.040  1.00 16.23 ? 240 ILE B CA    1 
ATOM   4195 C  C     . ILE B 1 240 ? 114.350 78.011  96.625  1.00 16.23 ? 240 ILE B C     1 
ATOM   4196 O  O     . ILE B 1 240 ? 115.257 77.803  97.446  1.00 16.23 ? 240 ILE B O     1 
ATOM   4197 C  CB    . ILE B 1 240 ? 112.155 76.758  96.585  1.00 16.23 ? 240 ILE B CB    1 
ATOM   4198 C  CG1   . ILE B 1 240 ? 110.652 76.869  96.840  1.00 16.23 ? 240 ILE B CG1   1 
ATOM   4199 C  CG2   . ILE B 1 240 ? 112.721 75.567  97.302  1.00 16.23 ? 240 ILE B CG2   1 
ATOM   4200 C  CD1   . ILE B 1 240 ? 109.893 75.594  96.565  1.00 16.23 ? 240 ILE B CD1   1 
ATOM   4201 N  N     . VAL B 1 241 ? 114.607 78.262  95.344  1.00 17.46 ? 241 VAL B N     1 
ATOM   4202 C  CA    . VAL B 1 241 ? 115.976 78.294  94.843  1.00 17.46 ? 241 VAL B CA    1 
ATOM   4203 C  C     . VAL B 1 241 ? 116.733 79.481  95.415  1.00 17.46 ? 241 VAL B C     1 
ATOM   4204 O  O     . VAL B 1 241 ? 117.925 79.378  95.707  1.00 17.46 ? 241 VAL B O     1 
ATOM   4205 C  CB    . VAL B 1 241 ? 115.983 78.295  93.306  1.00 17.46 ? 241 VAL B CB    1 
ATOM   4206 C  CG1   . VAL B 1 241 ? 117.389 78.360  92.773  1.00 17.46 ? 241 VAL B CG1   1 
ATOM   4207 C  CG2   . VAL B 1 241 ? 115.326 77.040  92.809  1.00 17.46 ? 241 VAL B CG2   1 
ATOM   4208 N  N     . ASP B 1 242 ? 116.080 80.636  95.530  1.00 17.89 ? 242 ASP B N     1 
ATOM   4209 C  CA    . ASP B 1 242 ? 116.707 81.797  96.154  1.00 17.89 ? 242 ASP B CA    1 
ATOM   4210 C  C     . ASP B 1 242 ? 117.182 81.466  97.569  1.00 17.89 ? 242 ASP B C     1 
ATOM   4211 O  O     . ASP B 1 242 ? 118.255 81.904  97.998  1.00 17.89 ? 242 ASP B O     1 
ATOM   4212 C  CB    . ASP B 1 242 ? 115.708 82.955  96.139  1.00 17.89 ? 242 ASP B CB    1 
ATOM   4213 C  CG    . ASP B 1 242 ? 116.199 84.166  96.860  1.00 17.89 ? 242 ASP B CG    1 
ATOM   4214 O  OD1   . ASP B 1 242 ? 116.097 84.198  98.096  1.00 17.89 ? 242 ASP B OD1   1 
ATOM   4215 O  OD2   . ASP B 1 242 ? 116.649 85.114  96.202  1.00 17.89 ? 242 ASP B OD2   1 
ATOM   4216 N  N     . SER B 1 243 ? 116.382 80.706  98.311  1.00 19.87 ? 243 SER B N     1 
ATOM   4217 C  CA    . SER B 1 243 ? 116.778 80.259  99.639  1.00 19.87 ? 243 SER B CA    1 
ATOM   4218 C  C     . SER B 1 243 ? 118.009 79.368  99.572  1.00 19.87 ? 243 SER B C     1 
ATOM   4219 O  O     . SER B 1 243 ? 118.940 79.514  100.371 1.00 19.87 ? 243 SER B O     1 
ATOM   4220 C  CB    . SER B 1 243 ? 115.621 79.520  100.305 1.00 19.87 ? 243 SER B CB    1 
ATOM   4221 O  OG    . SER B 1 243 ? 115.886 79.282  101.670 1.00 19.87 ? 243 SER B OG    1 
ATOM   4222 N  N     . PHE B 1 244 ? 118.018 78.413  98.641  1.00 20.65 ? 244 PHE B N     1 
ATOM   4223 C  CA    . PHE B 1 244 ? 119.205 77.572  98.484  1.00 20.65 ? 244 PHE B CA    1 
ATOM   4224 C  C     . PHE B 1 244 ? 120.444 78.398  98.165  1.00 20.65 ? 244 PHE B C     1 
ATOM   4225 O  O     . PHE B 1 244 ? 121.530 78.126  98.676  1.00 20.65 ? 244 PHE B O     1 
ATOM   4226 C  CB    . PHE B 1 244 ? 118.998 76.569  97.351  1.00 20.65 ? 244 PHE B CB    1 
ATOM   4227 C  CG    . PHE B 1 244 ? 117.910 75.579  97.583  1.00 20.65 ? 244 PHE B CG    1 
ATOM   4228 C  CD1   . PHE B 1 244 ? 117.473 75.286  98.853  1.00 20.65 ? 244 PHE B CD1   1 
ATOM   4229 C  CD2   . PHE B 1 244 ? 117.319 74.938  96.515  1.00 20.65 ? 244 PHE B CD2   1 
ATOM   4230 C  CE1   . PHE B 1 244 ? 116.490 74.366  99.046  1.00 20.65 ? 244 PHE B CE1   1 
ATOM   4231 C  CE2   . PHE B 1 244 ? 116.331 74.034  96.712  1.00 20.65 ? 244 PHE B CE2   1 
ATOM   4232 C  CZ    . PHE B 1 244 ? 115.924 73.739  97.972  1.00 20.65 ? 244 PHE B CZ    1 
ATOM   4233 N  N     . ILE B 1 245 ? 120.295 79.411  97.323  1.00 20.96 ? 245 ILE B N     1 
ATOM   4234 C  CA    . ILE B 1 245 ? 121.410 80.269  96.929  1.00 20.96 ? 245 ILE B CA    1 
ATOM   4235 C  C     . ILE B 1 245 ? 121.965 81.053  98.113  1.00 20.96 ? 245 ILE B C     1 
ATOM   4236 O  O     . ILE B 1 245 ? 123.182 81.114  98.317  1.00 20.96 ? 245 ILE B O     1 
ATOM   4237 C  CB    . ILE B 1 245 ? 120.993 81.180  95.768  1.00 20.96 ? 245 ILE B CB    1 
ATOM   4238 C  CG1   . ILE B 1 245 ? 120.869 80.341  94.508  1.00 20.96 ? 245 ILE B CG1   1 
ATOM   4239 C  CG2   . ILE B 1 245 ? 121.987 82.279  95.561  1.00 20.96 ? 245 ILE B CG2   1 
ATOM   4240 C  CD1   . ILE B 1 245 ? 120.151 81.032  93.402  1.00 20.96 ? 245 ILE B CD1   1 
ATOM   4241 N  N     . LYS B 1 246 ? 121.095 81.688  98.895  1.00 20.58 ? 246 LYS B N     1 
ATOM   4242 C  CA    . LYS B 1 246 ? 121.594 82.461  100.030 1.00 20.58 ? 246 LYS B CA    1 
ATOM   4243 C  C     . LYS B 1 246 ? 122.136 81.579  101.146 1.00 20.58 ? 246 LYS B C     1 
ATOM   4244 O  O     . LYS B 1 246 ? 123.091 81.965  101.824 1.00 20.58 ? 246 LYS B O     1 
ATOM   4245 C  CB    . LYS B 1 246 ? 120.520 83.414  100.562 1.00 20.58 ? 246 LYS B CB    1 
ATOM   4246 C  CG    . LYS B 1 246 ? 120.184 84.491  99.569  1.00 20.58 ? 246 LYS B CG    1 
ATOM   4247 C  CD    . LYS B 1 246 ? 119.287 85.581  100.099 1.00 20.58 ? 246 LYS B CD    1 
ATOM   4248 C  CE    . LYS B 1 246 ? 118.034 85.087  100.722 1.00 20.58 ? 246 LYS B CE    1 
ATOM   4249 N  NZ    . LYS B 1 246 ? 116.994 86.120  100.454 1.00 20.58 ? 246 LYS B NZ    1 
ATOM   4250 N  N     . GLN B 1 247 ? 121.573 80.404  101.348 1.00 24.37 ? 247 GLN B N     1 
ATOM   4251 C  CA    . GLN B 1 247 ? 122.028 79.515  102.403 1.00 24.37 ? 247 GLN B CA    1 
ATOM   4252 C  C     . GLN B 1 247 ? 123.168 78.595  101.971 1.00 24.37 ? 247 GLN B C     1 
ATOM   4253 O  O     . GLN B 1 247 ? 123.737 77.910  102.823 1.00 24.37 ? 247 GLN B O     1 
ATOM   4254 C  CB    . GLN B 1 247 ? 120.852 78.662  102.876 1.00 24.37 ? 247 GLN B CB    1 
ATOM   4255 C  CG    . GLN B 1 247 ? 119.671 79.445  103.434 1.00 24.37 ? 247 GLN B CG    1 
ATOM   4256 C  CD    . GLN B 1 247 ? 119.940 80.178  104.709 1.00 24.37 ? 247 GLN B CD    1 
ATOM   4257 O  OE1   . GLN B 1 247 ? 120.883 79.885  105.431 1.00 24.37 ? 247 GLN B OE1   1 
ATOM   4258 N  NE2   . GLN B 1 247 ? 119.090 81.132  105.011 1.00 24.37 ? 247 GLN B NE2   1 
ATOM   4259 N  N     . ARG B 1 248 ? 123.522 78.565  100.683 1.00 26.03 ? 248 ARG B N     1 
ATOM   4260 C  CA    . ARG B 1 248 ? 124.514 77.630  100.118 1.00 26.03 ? 248 ARG B CA    1 
ATOM   4261 C  C     . ARG B 1 248 ? 124.182 76.183  100.455 1.00 26.03 ? 248 ARG B C     1 
ATOM   4262 O  O     . ARG B 1 248 ? 125.030 75.407  100.884 1.00 26.03 ? 248 ARG B O     1 
ATOM   4263 C  CB    . ARG B 1 248 ? 125.945 77.961  100.547 1.00 26.03 ? 248 ARG B CB    1 
ATOM   4264 C  CG    . ARG B 1 248 ? 126.403 79.312  100.086 1.00 26.03 ? 248 ARG B CG    1 
ATOM   4265 C  CD    . ARG B 1 248 ? 127.879 79.544  100.269 1.00 26.03 ? 248 ARG B CD    1 
ATOM   4266 N  NE    . ARG B 1 248 ? 128.209 80.919  99.927  1.00 26.03 ? 248 ARG B NE    1 
ATOM   4267 C  CZ    . ARG B 1 248 ? 128.724 81.311  98.772  1.00 26.03 ? 248 ARG B CZ    1 
ATOM   4268 N  NH1   . ARG B 1 248 ? 129.042 80.445  97.829  1.00 26.03 ? 248 ARG B NH1   1 
ATOM   4269 N  NH2   . ARG B 1 248 ? 128.935 82.607  98.562  1.00 26.03 ? 248 ARG B NH2   1 
ATOM   4270 N  N     . THR B 1 249 ? 122.925 75.828  100.235 1.00 27.36 ? 249 THR B N     1 
ATOM   4271 C  CA    . THR B 1 249 ? 122.366 74.521  100.564 1.00 27.36 ? 249 THR B CA    1 
ATOM   4272 C  C     . THR B 1 249 ? 122.944 73.379  99.732  1.00 27.36 ? 249 THR B C     1 
ATOM   4273 O  O     . THR B 1 249 ? 122.631 73.233  98.554  1.00 27.36 ? 249 THR B O     1 
ATOM   4274 C  CB    . THR B 1 249 ? 120.853 74.565  100.385 1.00 27.36 ? 249 THR B CB    1 
ATOM   4275 O  OG1   . THR B 1 249 ? 120.294 75.609  101.190 1.00 27.36 ? 249 THR B OG1   1 
ATOM   4276 C  CG2   . THR B 1 249 ? 120.213 73.218  100.730 1.00 27.36 ? 249 THR B CG2   1 
ATOM   4277 N  N     . SER B 1 250 ? 123.815 72.588  100.346 1.00 32.08 ? 250 SER B N     1 
ATOM   4278 C  CA    . SER B 1 250 ? 124.287 71.294  99.852  1.00 32.08 ? 250 SER B CA    1 
ATOM   4279 C  C     . SER B 1 250 ? 124.334 71.086  98.335  1.00 32.08 ? 250 SER B C     1 
ATOM   4280 O  O     . SER B 1 250 ? 124.999 71.824  97.604  1.00 32.08 ? 250 SER B O     1 
ATOM   4281 C  CB    . SER B 1 250 ? 123.437 70.195  100.500 1.00 32.08 ? 250 SER B CB    1 
ATOM   4282 O  OG    . SER B 1 250 ? 123.975 68.898  100.281 1.00 32.08 ? 250 SER B OG    1 
ATOM   4283 N  N     . VAL B 1 251 ? 123.649 70.029  97.886  1.00 31.90 ? 251 VAL B N     1 
ATOM   4284 C  CA    . VAL B 1 251 ? 123.537 69.633  96.480  1.00 31.90 ? 251 VAL B CA    1 
ATOM   4285 C  C     . VAL B 1 251 ? 123.044 70.756  95.570  1.00 31.90 ? 251 VAL B C     1 
ATOM   4286 O  O     . VAL B 1 251 ? 123.538 70.936  94.444  1.00 31.90 ? 251 VAL B O     1 
ATOM   4287 C  CB    . VAL B 1 251 ? 122.567 68.439  96.400  1.00 31.90 ? 251 VAL B CB    1 
ATOM   4288 C  CG1   . VAL B 1 251 ? 122.283 68.041  94.972  1.00 31.90 ? 251 VAL B CG1   1 
ATOM   4289 C  CG2   . VAL B 1 251 ? 123.064 67.296  97.224  1.00 31.90 ? 251 VAL B CG2   1 
ATOM   4290 N  N     . TYR B 1 252 ? 122.115 71.564  96.062  1.00 27.75 ? 252 TYR B N     1 
ATOM   4291 C  CA    . TYR B 1 252 ? 121.469 72.568  95.226  1.00 27.75 ? 252 TYR B CA    1 
ATOM   4292 C  C     . TYR B 1 252 ? 122.331 73.790  94.934  1.00 27.75 ? 252 TYR B C     1 
ATOM   4293 O  O     . TYR B 1 252 ? 122.275 74.321  93.823  1.00 27.75 ? 252 TYR B O     1 
ATOM   4294 C  CB    . TYR B 1 252 ? 120.137 72.929  95.871  1.00 27.75 ? 252 TYR B CB    1 
ATOM   4295 C  CG    . TYR B 1 252 ? 119.208 71.730  96.017  1.00 27.75 ? 252 TYR B CG    1 
ATOM   4296 C  CD1   . TYR B 1 252 ? 118.691 71.089  94.906  1.00 27.75 ? 252 TYR B CD1   1 
ATOM   4297 C  CD2   . TYR B 1 252 ? 118.894 71.213  97.261  1.00 27.75 ? 252 TYR B CD2   1 
ATOM   4298 C  CE1   . TYR B 1 252 ? 117.867 69.995  95.034  1.00 27.75 ? 252 TYR B CE1   1 
ATOM   4299 C  CE2   . TYR B 1 252 ? 118.070 70.122  97.395  1.00 27.75 ? 252 TYR B CE2   1 
ATOM   4300 C  CZ    . TYR B 1 252 ? 117.557 69.524  96.280  1.00 27.75 ? 252 TYR B CZ    1 
ATOM   4301 O  OH    . TYR B 1 252 ? 116.729 68.445  96.413  1.00 27.75 ? 252 TYR B OH    1 
ATOM   4302 N  N     . ARG B 1 253 ? 123.164 74.236  95.874  1.00 28.16 ? 253 ARG B N     1 
ATOM   4303 C  CA    . ARG B 1 253 ? 124.051 75.364  95.579  1.00 28.16 ? 253 ARG B CA    1 
ATOM   4304 C  C     . ARG B 1 253 ? 125.128 74.956  94.584  1.00 28.16 ? 253 ARG B C     1 
ATOM   4305 O  O     . ARG B 1 253 ? 125.526 75.748  93.720  1.00 28.16 ? 253 ARG B O     1 
ATOM   4306 C  CB    . ARG B 1 253 ? 124.675 75.907  96.859  1.00 28.16 ? 253 ARG B CB    1 
ATOM   4307 C  CG    . ARG B 1 253 ? 125.616 77.075  96.652  1.00 28.16 ? 253 ARG B CG    1 
ATOM   4308 C  CD    . ARG B 1 253 ? 124.966 78.372  96.227  1.00 28.16 ? 253 ARG B CD    1 
ATOM   4309 N  NE    . ARG B 1 253 ? 125.938 79.192  95.519  1.00 28.16 ? 253 ARG B NE    1 
ATOM   4310 C  CZ    . ARG B 1 253 ? 126.060 80.506  95.615  1.00 28.16 ? 253 ARG B CZ    1 
ATOM   4311 N  NH1   . ARG B 1 253 ? 125.390 81.201  96.513  1.00 28.16 ? 253 ARG B NH1   1 
ATOM   4312 N  NH2   . ARG B 1 253 ? 126.910 81.135  94.814  1.00 28.16 ? 253 ARG B NH2   1 
ATOM   4313 N  N     . GLU B 1 254 ? 125.646 73.734  94.736  1.00 32.91 ? 254 GLU B N     1 
ATOM   4314 C  CA    . GLU B 1 254 ? 126.619 73.192  93.797  1.00 32.91 ? 254 GLU B CA    1 
ATOM   4315 C  C     . GLU B 1 254 ? 126.033 73.141  92.397  1.00 32.91 ? 254 GLU B C     1 
ATOM   4316 O  O     . GLU B 1 254 ? 126.674 73.552  91.425  1.00 32.91 ? 254 GLU B O     1 
ATOM   4317 C  CB    . GLU B 1 254 ? 127.032 71.791  94.234  1.00 32.91 ? 254 GLU B CB    1 
ATOM   4318 C  CG    . GLU B 1 254 ? 127.769 71.697  95.548  1.00 32.91 ? 254 GLU B CG    1 
ATOM   4319 C  CD    . GLU B 1 254 ? 128.108 70.254  95.897  1.00 32.91 ? 254 GLU B CD    1 
ATOM   4320 O  OE1   . GLU B 1 254 ? 127.294 69.365  95.567  1.00 32.91 ? 254 GLU B OE1   1 
ATOM   4321 O  OE2   . GLU B 1 254 ? 129.180 70.003  96.494  1.00 32.91 ? 254 GLU B OE2   1 
ATOM   4322 N  N     . LEU B 1 255 ? 124.793 72.663  92.284  1.00 29.45 ? 255 LEU B N     1 
ATOM   4323 C  CA    . LEU B 1 255 ? 124.138 72.604  90.982  1.00 29.45 ? 255 LEU B CA    1 
ATOM   4324 C  C     . LEU B 1 255 ? 123.917 73.992  90.395  1.00 29.45 ? 255 LEU B C     1 
ATOM   4325 O  O     . LEU B 1 255 ? 124.091 74.199  89.188  1.00 29.45 ? 255 LEU B O     1 
ATOM   4326 C  CB    . LEU B 1 255 ? 122.825 71.856  91.116  1.00 29.45 ? 255 LEU B CB    1 
ATOM   4327 C  CG    . LEU B 1 255 ? 122.009 71.693  89.856  1.00 29.45 ? 255 LEU B CG    1 
ATOM   4328 C  CD1   . LEU B 1 255 ? 122.805 70.936  88.825  1.00 29.45 ? 255 LEU B CD1   1 
ATOM   4329 C  CD2   . LEU B 1 255 ? 120.794 70.913  90.231  1.00 29.45 ? 255 LEU B CD2   1 
ATOM   4330 N  N     . TYR B 1 256 ? 123.566 74.963  91.236  1.00 28.54 ? 256 TYR B N     1 
ATOM   4331 C  CA    . TYR B 1 256 ? 123.418 76.330  90.761  1.00 28.54 ? 256 TYR B CA    1 
ATOM   4332 C  C     . TYR B 1 256 ? 124.727 76.872  90.207  1.00 28.54 ? 256 TYR B C     1 
ATOM   4333 O  O     . TYR B 1 256 ? 124.758 77.391  89.089  1.00 28.54 ? 256 TYR B O     1 
ATOM   4334 C  CB    . TYR B 1 256 ? 122.891 77.217  91.886  1.00 28.54 ? 256 TYR B CB    1 
ATOM   4335 C  CG    . TYR B 1 256 ? 122.947 78.688  91.603  1.00 28.54 ? 256 TYR B CG    1 
ATOM   4336 C  CD1   . TYR B 1 256 ? 122.060 79.293  90.738  1.00 28.54 ? 256 TYR B CD1   1 
ATOM   4337 C  CD2   . TYR B 1 256 ? 123.889 79.475  92.225  1.00 28.54 ? 256 TYR B CD2   1 
ATOM   4338 C  CE1   . TYR B 1 256 ? 122.124 80.646  90.496  1.00 28.54 ? 256 TYR B CE1   1 
ATOM   4339 C  CE2   . TYR B 1 256 ? 123.959 80.823  91.988  1.00 28.54 ? 256 TYR B CE2   1 
ATOM   4340 C  CZ    . TYR B 1 256 ? 123.080 81.401  91.123  1.00 28.54 ? 256 TYR B CZ    1 
ATOM   4341 O  OH    . TYR B 1 256 ? 123.156 82.747  90.905  1.00 28.54 ? 256 TYR B OH    1 
ATOM   4342 N  N     . ASP B 1 257 ? 125.816 76.789  90.984  1.00 31.84 ? 257 ASP B N     1 
ATOM   4343 C  CA    . ASP B 1 257 ? 127.118 77.279  90.513  1.00 31.84 ? 257 ASP B CA    1 
ATOM   4344 C  C     . ASP B 1 257 ? 127.573 76.572  89.240  1.00 31.84 ? 257 ASP B C     1 
ATOM   4345 O  O     . ASP B 1 257 ? 128.004 77.217  88.277  1.00 31.84 ? 257 ASP B O     1 
ATOM   4346 C  CB    . ASP B 1 257 ? 128.196 77.111  91.591  1.00 31.84 ? 257 ASP B CB    1 
ATOM   4347 C  CG    . ASP B 1 257 ? 128.018 78.023  92.793  1.00 31.84 ? 257 ASP B CG    1 
ATOM   4348 O  OD1   . ASP B 1 257 ? 127.305 79.041  92.697  1.00 31.84 ? 257 ASP B OD1   1 
ATOM   4349 O  OD2   . ASP B 1 257 ? 128.608 77.715  93.854  1.00 31.84 ? 257 ASP B OD2   1 
ATOM   4350 N  N     . ALA B 1 258 ? 127.464 75.248  89.207  1.00 33.63 ? 258 ALA B N     1 
ATOM   4351 C  CA    . ALA B 1 258 ? 127.890 74.490  88.036  1.00 33.63 ? 258 ALA B CA    1 
ATOM   4352 C  C     . ALA B 1 258 ? 127.113 74.879  86.787  1.00 33.63 ? 258 ALA B C     1 
ATOM   4353 O  O     . ALA B 1 258 ? 127.709 75.117  85.732  1.00 33.63 ? 258 ALA B O     1 
ATOM   4354 C  CB    . ALA B 1 258 ? 127.747 72.992  88.308  1.00 33.63 ? 258 ALA B CB    1 
ATOM   4355 N  N     . GLU B 1 259 ? 125.783 74.952  86.876  1.00 34.54 ? 259 GLU B N     1 
ATOM   4356 C  CA    . GLU B 1 259 ? 124.997 75.338  85.707  1.00 34.54 ? 259 GLU B CA    1 
ATOM   4357 C  C     . GLU B 1 259 ? 125.202 76.797  85.317  1.00 34.54 ? 259 GLU B C     1 
ATOM   4358 O  O     . GLU B 1 259 ? 125.246 77.109  84.129  1.00 34.54 ? 259 GLU B O     1 
ATOM   4359 C  CB    . GLU B 1 259 ? 123.518 75.042  85.932  1.00 34.54 ? 259 GLU B CB    1 
ATOM   4360 C  CG    . GLU B 1 259 ? 122.664 75.288  84.694  1.00 34.54 ? 259 GLU B CG    1 
ATOM   4361 C  CD    . GLU B 1 259 ? 122.924 74.333  83.560  1.00 34.54 ? 259 GLU B CD    1 
ATOM   4362 O  OE1   . GLU B 1 259 ? 123.740 73.409  83.712  1.00 34.54 ? 259 GLU B OE1   1 
ATOM   4363 O  OE2   . GLU B 1 259 ? 122.317 74.524  82.487  1.00 34.54 ? 259 GLU B OE2   1 
ATOM   4364 N  N     . LYS B 1 260 ? 125.280 77.709  86.282  1.00 31.51 ? 260 LYS B N     1 
ATOM   4365 C  CA    . LYS B 1 260 ? 125.497 79.112  85.944  1.00 31.51 ? 260 LYS B CA    1 
ATOM   4366 C  C     . LYS B 1 260 ? 126.832 79.297  85.231  1.00 31.51 ? 260 LYS B C     1 
ATOM   4367 O  O     . LYS B 1 260 ? 126.934 80.069  84.269  1.00 31.51 ? 260 LYS B O     1 
ATOM   4368 C  CB    . LYS B 1 260 ? 125.406 79.957  87.217  1.00 31.51 ? 260 LYS B CB    1 
ATOM   4369 C  CG    . LYS B 1 260 ? 125.354 81.450  87.010  1.00 31.51 ? 260 LYS B CG    1 
ATOM   4370 C  CD    . LYS B 1 260 ? 125.632 82.166  88.313  1.00 31.51 ? 260 LYS B CD    1 
ATOM   4371 C  CE    . LYS B 1 260 ? 125.530 83.663  88.161  1.00 31.51 ? 260 LYS B CE    1 
ATOM   4372 N  NZ    . LYS B 1 260 ? 125.947 84.361  89.409  1.00 31.51 ? 260 LYS B NZ    1 
ATOM   4373 N  N     . ALA B 1 261 ? 127.842 78.509  85.619  1.00 35.64 ? 261 ALA B N     1 
ATOM   4374 C  CA    . ALA B 1 261 ? 129.134 78.562  84.939  1.00 35.64 ? 261 ALA B CA    1 
ATOM   4375 C  C     . ALA B 1 261 ? 129.059 77.929  83.555  1.00 35.64 ? 261 ALA B C     1 
ATOM   4376 O  O     . ALA B 1 261 ? 129.573 78.485  82.581  1.00 35.64 ? 261 ALA B O     1 
ATOM   4377 C  CB    . ALA B 1 261 ? 130.200 77.871  85.785  1.00 35.64 ? 261 ALA B CB    1 
ATOM   4378 N  N     . ARG B 1 262 ? 128.424 76.763  83.450  1.00 38.31 ? 262 ARG B N     1 
ATOM   4379 C  CA    . ARG B 1 262 ? 128.272 76.095  82.161  1.00 38.31 ? 262 ARG B CA    1 
ATOM   4380 C  C     . ARG B 1 262 ? 127.476 76.931  81.167  1.00 38.31 ? 262 ARG B C     1 
ATOM   4381 O  O     . ARG B 1 262 ? 127.717 76.851  79.959  1.00 38.31 ? 262 ARG B O     1 
ATOM   4382 C  CB    . ARG B 1 262 ? 127.600 74.738  82.366  1.00 38.31 ? 262 ARG B CB    1 
ATOM   4383 C  CG    . ARG B 1 262 ? 127.560 73.851  81.142  1.00 38.31 ? 262 ARG B CG    1 
ATOM   4384 C  CD    . ARG B 1 262 ? 126.923 72.496  81.456  1.00 38.31 ? 262 ARG B CD    1 
ATOM   4385 N  NE    . ARG B 1 262 ? 125.471 72.606  81.490  1.00 38.31 ? 262 ARG B NE    1 
ATOM   4386 C  CZ    . ARG B 1 262 ? 124.655 72.176  80.537  1.00 38.31 ? 262 ARG B CZ    1 
ATOM   4387 N  NH1   . ARG B 1 262 ? 125.109 71.526  79.480  1.00 38.31 ? 262 ARG B NH1   1 
ATOM   4388 N  NH2   . ARG B 1 262 ? 123.352 72.422  80.640  1.00 38.31 ? 262 ARG B NH2   1 
ATOM   4389 N  N     . GLN B 1 263 ? 126.519 77.719  81.644  1.00 37.04 ? 263 GLN B N     1 
ATOM   4390 C  CA    . GLN B 1 263 ? 125.668 78.512  80.768  1.00 37.04 ? 263 GLN B CA    1 
ATOM   4391 C  C     . GLN B 1 263 ? 126.194 79.901  80.449  1.00 37.04 ? 263 GLN B C     1 
ATOM   4392 O  O     . GLN B 1 263 ? 125.815 80.453  79.415  1.00 37.04 ? 263 GLN B O     1 
ATOM   4393 C  CB    . GLN B 1 263 ? 124.264 78.624  81.363  1.00 37.04 ? 263 GLN B CB    1 
ATOM   4394 C  CG    . GLN B 1 263 ? 123.499 77.313  81.353  1.00 37.04 ? 263 GLN B CG    1 
ATOM   4395 C  CD    . GLN B 1 263 ? 123.047 76.904  79.977  1.00 37.04 ? 263 GLN B CD    1 
ATOM   4396 O  OE1   . GLN B 1 263 ? 123.309 77.585  78.997  1.00 37.04 ? 263 GLN B OE1   1 
ATOM   4397 N  NE2   . GLN B 1 263 ? 122.343 75.795  79.899  1.00 37.04 ? 263 GLN B NE2   1 
ATOM   4398 N  N     . ARG B 1 264 ? 127.022 80.511  81.295  1.00 39.13 ? 264 ARG B N     1 
ATOM   4399 C  CA    . ARG B 1 264 ? 127.481 81.865  80.979  1.00 39.13 ? 264 ARG B CA    1 
ATOM   4400 C  C     . ARG B 1 264 ? 128.183 82.008  79.624  1.00 39.13 ? 264 ARG B C     1 
ATOM   4401 O  O     . ARG B 1 264 ? 128.030 83.072  78.998  1.00 39.13 ? 264 ARG B O     1 
ATOM   4402 C  CB    . ARG B 1 264 ? 128.364 82.381  82.120  1.00 39.13 ? 264 ARG B CB    1 
ATOM   4403 C  CG    . ARG B 1 264 ? 128.801 83.827  81.957  1.00 39.13 ? 264 ARG B CG    1 
ATOM   4404 C  CD    . ARG B 1 264 ? 127.646 84.733  81.692  1.00 39.13 ? 264 ARG B CD    1 
ATOM   4405 N  NE    . ARG B 1 264 ? 128.030 86.133  81.760  1.00 39.13 ? 264 ARG B NE    1 
ATOM   4406 C  CZ    . ARG B 1 264 ? 128.086 86.945  80.716  1.00 39.13 ? 264 ARG B CZ    1 
ATOM   4407 N  NH1   . ARG B 1 264 ? 127.895 86.502  79.489  1.00 39.13 ? 264 ARG B NH1   1 
ATOM   4408 N  NH2   . ARG B 1 264 ? 128.342 88.235  80.910  1.00 39.13 ? 264 ARG B NH2   1 
ATOM   4409 N  N     . PRO B 1 265 ? 128.964 81.041  79.129  1.00 39.18 ? 265 PRO B N     1 
ATOM   4410 C  CA    . PRO B 1 265 ? 129.503 81.159  77.762  1.00 39.18 ? 265 PRO B CA    1 
ATOM   4411 C  C     . PRO B 1 265 ? 128.456 81.261  76.658  1.00 39.18 ? 265 PRO B C     1 
ATOM   4412 O  O     . PRO B 1 265 ? 128.791 81.732  75.569  1.00 39.18 ? 265 PRO B O     1 
ATOM   4413 C  CB    . PRO B 1 265 ? 130.330 79.883  77.609  1.00 39.18 ? 265 PRO B CB    1 
ATOM   4414 C  CG    . PRO B 1 265 ? 130.771 79.584  78.967  1.00 39.18 ? 265 PRO B CG    1 
ATOM   4415 C  CD    . PRO B 1 265 ? 129.615 79.935  79.844  1.00 39.18 ? 265 PRO B CD    1 
ATOM   4416 N  N     . LYS B 1 266 ? 127.212 80.840  76.892  1.00 39.91 ? 266 LYS B N     1 
ATOM   4417 C  CA    . LYS B 1 266 ? 126.162 80.803  75.875  1.00 39.91 ? 266 LYS B CA    1 
ATOM   4418 C  C     . LYS B 1 266 ? 125.172 81.968  75.926  1.00 39.91 ? 266 LYS B C     1 
ATOM   4419 O  O     . LYS B 1 266 ? 124.222 81.974  75.142  1.00 39.91 ? 266 LYS B O     1 
ATOM   4420 C  CB    . LYS B 1 266 ? 125.387 79.492  75.999  1.00 39.91 ? 266 LYS B CB    1 
ATOM   4421 C  CG    . LYS B 1 266 ? 126.279 78.276  76.086  1.00 39.91 ? 266 LYS B CG    1 
ATOM   4422 C  CD    . LYS B 1 266 ? 125.496 76.990  75.987  1.00 39.91 ? 266 LYS B CD    1 
ATOM   4423 C  CE    . LYS B 1 266 ? 126.367 75.803  76.359  1.00 39.91 ? 266 LYS B CE    1 
ATOM   4424 N  NZ    . LYS B 1 266 ? 125.684 74.503  76.131  1.00 39.91 ? 266 LYS B NZ    1 
ATOM   4425 N  N     . VAL B 1 267 ? 125.355 82.946  76.818  1.00 40.14 ? 267 VAL B N     1 
ATOM   4426 C  CA    . VAL B 1 267 ? 124.414 84.049  76.984  1.00 40.14 ? 267 VAL B CA    1 
ATOM   4427 C  C     . VAL B 1 267 ? 125.185 85.353  77.132  1.00 40.14 ? 267 VAL B C     1 
ATOM   4428 O  O     . VAL B 1 267 ? 126.371 85.371  77.463  1.00 40.14 ? 267 VAL B O     1 
ATOM   4429 C  CB    . VAL B 1 267 ? 123.462 83.859  78.191  1.00 40.14 ? 267 VAL B CB    1 
ATOM   4430 C  CG1   . VAL B 1 267 ? 122.658 82.581  78.046  1.00 40.14 ? 267 VAL B CG1   1 
ATOM   4431 C  CG2   . VAL B 1 267 ? 124.247 83.843  79.500  1.00 40.14 ? 267 VAL B CG2   1 
ATOM   4432 N  N     . GLU B 1 268 ? 124.483 86.455  76.865  1.00 45.52 ? 268 GLU B N     1 
ATOM   4433 C  CA    . GLU B 1 268 ? 125.092 87.777  76.818  1.00 45.52 ? 268 GLU B CA    1 
ATOM   4434 C  C     . GLU B 1 268 ? 125.276 88.480  78.163  1.00 45.52 ? 268 GLU B C     1 
ATOM   4435 O  O     . GLU B 1 268 ? 126.063 89.428  78.225  1.00 45.52 ? 268 GLU B O     1 
ATOM   4436 C  CB    . GLU B 1 268 ? 124.284 88.653  75.866  1.00 45.52 ? 268 GLU B CB    1 
ATOM   4437 C  CG    . GLU B 1 268 ? 124.257 88.039  74.473  1.00 45.52 ? 268 GLU B CG    1 
ATOM   4438 C  CD    . GLU B 1 268 ? 123.790 88.972  73.391  1.00 45.52 ? 268 GLU B CD    1 
ATOM   4439 O  OE1   . GLU B 1 268 ? 123.026 89.910  73.687  1.00 45.52 ? 268 GLU B OE1   1 
ATOM   4440 O  OE2   . GLU B 1 268 ? 124.185 88.753  72.230  1.00 45.52 ? 268 GLU B OE2   1 
ATOM   4441 N  N     . SER B 1 269 ? 124.602 88.078  79.240  1.00 38.25 ? 269 SER B N     1 
ATOM   4442 C  CA    . SER B 1 269 ? 124.864 88.760  80.503  1.00 38.25 ? 269 SER B CA    1 
ATOM   4443 C  C     . SER B 1 269 ? 124.772 87.804  81.679  1.00 38.25 ? 269 SER B C     1 
ATOM   4444 O  O     . SER B 1 269 ? 124.212 86.713  81.575  1.00 38.25 ? 269 SER B O     1 
ATOM   4445 C  CB    . SER B 1 269 ? 123.923 89.945  80.714  1.00 38.25 ? 269 SER B CB    1 
ATOM   4446 O  OG    . SER B 1 269 ? 122.746 89.563  81.382  1.00 38.25 ? 269 SER B OG    1 
ATOM   4447 N  N     . ASP B 1 270 ? 125.370 88.231  82.798  1.00 37.77 ? 270 ASP B N     1 
ATOM   4448 C  CA    . ASP B 1 270 ? 125.331 87.442  84.026  1.00 37.77 ? 270 ASP B CA    1 
ATOM   4449 C  C     . ASP B 1 270 ? 123.903 87.160  84.472  1.00 37.77 ? 270 ASP B C     1 
ATOM   4450 O  O     . ASP B 1 270 ? 123.605 86.054  84.933  1.00 37.77 ? 270 ASP B O     1 
ATOM   4451 C  CB    . ASP B 1 270 ? 126.091 88.146  85.161  1.00 37.77 ? 270 ASP B CB    1 
ATOM   4452 C  CG    . ASP B 1 270 ? 127.566 88.384  84.853  1.00 37.77 ? 270 ASP B CG    1 
ATOM   4453 O  OD1   . ASP B 1 270 ? 128.092 87.809  83.887  1.00 37.77 ? 270 ASP B OD1   1 
ATOM   4454 O  OD2   . ASP B 1 270 ? 128.218 89.135  85.609  1.00 37.77 ? 270 ASP B OD2   1 
ATOM   4455 N  N     . GLY B 1 271 ? 123.007 88.145  84.356  1.00 32.91 ? 271 GLY B N     1 
ATOM   4456 C  CA    . GLY B 1 271 ? 121.623 87.924  84.748  1.00 32.91 ? 271 GLY B CA    1 
ATOM   4457 C  C     . GLY B 1 271 ? 120.908 86.837  83.967  1.00 32.91 ? 271 GLY B C     1 
ATOM   4458 O  O     . GLY B 1 271 ? 120.106 86.092  84.533  1.00 32.91 ? 271 GLY B O     1 
ATOM   4459 N  N     . HIS B 1 272 ? 121.253 86.667  82.694  1.00 30.73 ? 272 HIS B N     1 
ATOM   4460 C  CA    . HIS B 1 272 ? 120.666 85.591  81.908  1.00 30.73 ? 272 HIS B CA    1 
ATOM   4461 C  C     . HIS B 1 272 ? 121.209 84.242  82.356  1.00 30.73 ? 272 HIS B C     1 
ATOM   4462 O  O     . HIS B 1 272 ? 120.453 83.271  82.453  1.00 30.73 ? 272 HIS B O     1 
ATOM   4463 C  CB    . HIS B 1 272 ? 120.918 85.845  80.421  1.00 30.73 ? 272 HIS B CB    1 
ATOM   4464 C  CG    . HIS B 1 272 ? 120.097 84.996  79.495  1.00 30.73 ? 272 HIS B CG    1 
ATOM   4465 N  ND1   . HIS B 1 272 ? 119.284 83.969  79.925  1.00 30.73 ? 272 HIS B ND1   1 
ATOM   4466 C  CD2   . HIS B 1 272 ? 119.942 85.054  78.152  1.00 30.73 ? 272 HIS B CD2   1 
ATOM   4467 C  CE1   . HIS B 1 272 ? 118.688 83.415  78.886  1.00 30.73 ? 272 HIS B CE1   1 
ATOM   4468 N  NE2   . HIS B 1 272 ? 119.072 84.054  77.798  1.00 30.73 ? 272 HIS B NE2   1 
ATOM   4469 N  N     . ALA B 1 273 ? 122.513 84.156  82.630  1.00 31.28 ? 273 ALA B N     1 
ATOM   4470 C  CA    . ALA B 1 273 ? 123.071 82.903  83.127  1.00 31.28 ? 273 ALA B CA    1 
ATOM   4471 C  C     . ALA B 1 273 ? 122.469 82.559  84.478  1.00 31.28 ? 273 ALA B C     1 
ATOM   4472 O  O     . ALA B 1 273 ? 122.200 81.390  84.772  1.00 31.28 ? 273 ALA B O     1 
ATOM   4473 C  CB    . ALA B 1 273 ? 124.590 82.994  83.228  1.00 31.28 ? 273 ALA B CB    1 
ATOM   4474 N  N     . HIS B 1 274 ? 122.231 83.580  85.300  1.00 26.81 ? 274 HIS B N     1 
ATOM   4475 C  CA    . HIS B 1 274 ? 121.590 83.403  86.593  1.00 26.81 ? 274 HIS B CA    1 
ATOM   4476 C  C     . HIS B 1 274 ? 120.199 82.809  86.419  1.00 26.81 ? 274 HIS B C     1 
ATOM   4477 O  O     . HIS B 1 274 ? 119.869 81.799  87.043  1.00 26.81 ? 274 HIS B O     1 
ATOM   4478 C  CB    . HIS B 1 274 ? 121.557 84.758  87.307  1.00 26.81 ? 274 HIS B CB    1 
ATOM   4479 C  CG    . HIS B 1 274 ? 120.828 84.773  88.615  1.00 26.81 ? 274 HIS B CG    1 
ATOM   4480 N  ND1   . HIS B 1 274 ? 121.092 83.887  89.635  1.00 26.81 ? 274 HIS B ND1   1 
ATOM   4481 C  CD2   . HIS B 1 274 ? 119.884 85.619  89.091  1.00 26.81 ? 274 HIS B CD2   1 
ATOM   4482 C  CE1   . HIS B 1 274 ? 120.316 84.161  90.666  1.00 26.81 ? 274 HIS B CE1   1 
ATOM   4483 N  NE2   . HIS B 1 274 ? 119.576 85.211  90.364  1.00 26.81 ? 274 HIS B NE2   1 
ATOM   4484 N  N     . ASN B 1 275 ? 119.370 83.425  85.571  1.00 24.82 ? 275 ASN B N     1 
ATOM   4485 C  CA    . ASN B 1 275 ? 118.029 82.899  85.321  1.00 24.82 ? 275 ASN B CA    1 
ATOM   4486 C  C     . ASN B 1 275 ? 118.047 81.481  84.758  1.00 24.82 ? 275 ASN B C     1 
ATOM   4487 O  O     . ASN B 1 275 ? 117.221 80.652  85.147  1.00 24.82 ? 275 ASN B O     1 
ATOM   4488 C  CB    . ASN B 1 275 ? 117.250 83.830  84.398  1.00 24.82 ? 275 ASN B CB    1 
ATOM   4489 C  CG    . ASN B 1 275 ? 116.866 85.106  85.074  1.00 24.82 ? 275 ASN B CG    1 
ATOM   4490 O  OD1   . ASN B 1 275 ? 116.938 85.207  86.282  1.00 24.82 ? 275 ASN B OD1   1 
ATOM   4491 N  ND2   . ASN B 1 275 ? 116.396 86.069  84.312  1.00 24.82 ? 275 ASN B ND2   1 
ATOM   4492 N  N     . ARG B 1 276 ? 118.994 81.153  83.885  1.00 27.83 ? 276 ARG B N     1 
ATOM   4493 C  CA    . ARG B 1 276 ? 119.058 79.774  83.396  1.00 27.83 ? 276 ARG B CA    1 
ATOM   4494 C  C     . ARG B 1 276 ? 119.442 78.796  84.495  1.00 27.83 ? 276 ARG B C     1 
ATOM   4495 O  O     . ARG B 1 276 ? 118.867 77.705  84.595  1.00 27.83 ? 276 ARG B O     1 
ATOM   4496 C  CB    . ARG B 1 276 ? 120.026 79.651  82.227  1.00 27.83 ? 276 ARG B CB    1 
ATOM   4497 C  CG    . ARG B 1 276 ? 119.502 80.220  80.917  1.00 27.83 ? 276 ARG B CG    1 
ATOM   4498 C  CD    . ARG B 1 276 ? 120.462 79.916  79.773  1.00 27.83 ? 276 ARG B CD    1 
ATOM   4499 N  NE    . ARG B 1 276 ? 119.850 80.199  78.483  1.00 27.83 ? 276 ARG B NE    1 
ATOM   4500 C  CZ    . ARG B 1 276 ? 120.355 79.835  77.316  1.00 27.83 ? 276 ARG B CZ    1 
ATOM   4501 N  NH1   . ARG B 1 276 ? 121.498 79.183  77.233  1.00 27.83 ? 276 ARG B NH1   1 
ATOM   4502 N  NH2   . ARG B 1 276 ? 119.700 80.144  76.204  1.00 27.83 ? 276 ARG B NH2   1 
ATOM   4503 N  N     . ALA B 1 277 ? 120.423 79.154  85.319  1.00 25.85 ? 277 ALA B N     1 
ATOM   4504 C  CA    . ALA B 1 277 ? 120.793 78.293  86.432  1.00 25.85 ? 277 ALA B CA    1 
ATOM   4505 C  C     . ALA B 1 277 ? 119.635 78.129  87.410  1.00 25.85 ? 277 ALA B C     1 
ATOM   4506 O  O     . ALA B 1 277 ? 119.393 77.028  87.906  1.00 25.85 ? 277 ALA B O     1 
ATOM   4507 C  CB    . ALA B 1 277 ? 122.018 78.857  87.137  1.00 25.85 ? 277 ALA B CB    1 
ATOM   4508 N  N     . VAL B 1 278 ? 118.941 79.225  87.731  1.00 23.22 ? 278 VAL B N     1 
ATOM   4509 C  CA    . VAL B 1 278 ? 117.791 79.168  88.634  1.00 23.22 ? 278 VAL B CA    1 
ATOM   4510 C  C     . VAL B 1 278 ? 116.740 78.213  88.089  1.00 23.22 ? 278 VAL B C     1 
ATOM   4511 O  O     . VAL B 1 278 ? 116.212 77.366  88.813  1.00 23.22 ? 278 VAL B O     1 
ATOM   4512 C  CB    . VAL B 1 278 ? 117.209 80.572  88.860  1.00 23.22 ? 278 VAL B CB    1 
ATOM   4513 C  CG1   . VAL B 1 278 ? 115.867 80.481  89.552  1.00 23.22 ? 278 VAL B CG1   1 
ATOM   4514 C  CG2   . VAL B 1 278 ? 118.156 81.412  89.672  1.00 23.22 ? 278 VAL B CG2   1 
ATOM   4515 N  N     . ARG B 1 279 ? 116.408 78.353  86.808  1.00 22.01 ? 279 ARG B N     1 
ATOM   4516 C  CA    . ARG B 1 279 ? 115.470 77.443  86.173  1.00 22.01 ? 279 ARG B CA    1 
ATOM   4517 C  C     . ARG B 1 279 ? 115.936 76.000  86.287  1.00 22.01 ? 279 ARG B C     1 
ATOM   4518 O  O     . ARG B 1 279 ? 115.151 75.113  86.632  1.00 22.01 ? 279 ARG B O     1 
ATOM   4519 C  CB    . ARG B 1 279 ? 115.297 77.842  84.714  1.00 22.01 ? 279 ARG B CB    1 
ATOM   4520 C  CG    . ARG B 1 279 ? 114.221 77.113  83.963  1.00 22.01 ? 279 ARG B CG    1 
ATOM   4521 C  CD    . ARG B 1 279 ? 114.182 77.584  82.527  1.00 22.01 ? 279 ARG B CD    1 
ATOM   4522 N  NE    . ARG B 1 279 ? 113.052 77.029  81.793  1.00 22.01 ? 279 ARG B NE    1 
ATOM   4523 C  CZ    . ARG B 1 279 ? 111.854 77.592  81.742  1.00 22.01 ? 279 ARG B CZ    1 
ATOM   4524 N  NH1   . ARG B 1 279 ? 111.607 78.739  82.339  1.00 22.01 ? 279 ARG B NH1   1 
ATOM   4525 N  NH2   . ARG B 1 279 ? 110.876 76.979  81.094  1.00 22.01 ? 279 ARG B NH2   1 
ATOM   4526 N  N     . LYS B 1 280 ? 117.210 75.740  85.989  1.00 25.12 ? 280 LYS B N     1 
ATOM   4527 C  CA    . LYS B 1 280 ? 117.740 74.383  86.094  1.00 25.12 ? 280 LYS B CA    1 
ATOM   4528 C  C     . LYS B 1 280 ? 117.609 73.815  87.508  1.00 25.12 ? 280 LYS B C     1 
ATOM   4529 O  O     . LYS B 1 280 ? 117.161 72.676  87.694  1.00 25.12 ? 280 LYS B O     1 
ATOM   4530 C  CB    . LYS B 1 280 ? 119.196 74.368  85.632  1.00 25.12 ? 280 LYS B CB    1 
ATOM   4531 C  CG    . LYS B 1 280 ? 119.867 73.016  85.744  1.00 25.12 ? 280 LYS B CG    1 
ATOM   4532 C  CD    . LYS B 1 280 ? 119.169 72.006  84.867  1.00 25.12 ? 280 LYS B CD    1 
ATOM   4533 C  CE    . LYS B 1 280 ? 119.846 70.653  84.936  1.00 25.12 ? 280 LYS B CE    1 
ATOM   4534 N  NZ    . LYS B 1 280 ? 119.269 69.713  83.947  1.00 25.12 ? 280 LYS B NZ    1 
ATOM   4535 N  N     . VAL B 1 281 ? 117.971 74.602  88.518  1.00 23.18 ? 281 VAL B N     1 
ATOM   4536 C  CA    . VAL B 1 281 ? 117.886 74.125  89.894  1.00 23.18 ? 281 VAL B CA    1 
ATOM   4537 C  C     . VAL B 1 281 ? 116.437 73.887  90.296  1.00 23.18 ? 281 VAL B C     1 
ATOM   4538 O  O     . VAL B 1 281 ? 116.128 72.890  90.952  1.00 23.18 ? 281 VAL B O     1 
ATOM   4539 C  CB    . VAL B 1 281 ? 118.576 75.113  90.852  1.00 23.18 ? 281 VAL B CB    1 
ATOM   4540 C  CG1   . VAL B 1 281 ? 118.511 74.597  92.265  1.00 23.18 ? 281 VAL B CG1   1 
ATOM   4541 C  CG2   . VAL B 1 281 ? 120.008 75.335  90.451  1.00 23.18 ? 281 VAL B CG2   1 
ATOM   4542 N  N     . ALA B 1 282 ? 115.532 74.801  89.925  1.00 21.76 ? 282 ALA B N     1 
ATOM   4543 C  CA    . ALA B 1 282 ? 114.112 74.635  90.221  1.00 21.76 ? 282 ALA B CA    1 
ATOM   4544 C  C     . ALA B 1 282 ? 113.560 73.354  89.615  1.00 21.76 ? 282 ALA B C     1 
ATOM   4545 O  O     . ALA B 1 282 ? 112.846 72.601  90.278  1.00 21.76 ? 282 ALA B O     1 
ATOM   4546 C  CB    . ALA B 1 282 ? 113.330 75.840  89.710  1.00 21.76 ? 282 ALA B CB    1 
ATOM   4547 N  N     . LYS B 1 283 ? 113.871 73.100  88.347  1.00 21.72 ? 283 LYS B N     1 
ATOM   4548 C  CA    . LYS B 1 283 ? 113.435 71.869  87.695  1.00 21.72 ? 283 LYS B CA    1 
ATOM   4549 C  C     . LYS B 1 283 ? 113.973 70.626  88.399  1.00 21.72 ? 283 LYS B C     1 
ATOM   4550 O  O     . LYS B 1 283 ? 113.247 69.640  88.570  1.00 21.72 ? 283 LYS B O     1 
ATOM   4551 C  CB    . LYS B 1 283 ? 113.831 71.886  86.227  1.00 21.72 ? 283 LYS B CB    1 
ATOM   4552 C  CG    . LYS B 1 283 ? 113.010 72.869  85.441  1.00 21.72 ? 283 LYS B CG    1 
ATOM   4553 C  CD    . LYS B 1 283 ? 113.343 72.888  83.980  1.00 21.72 ? 283 LYS B CD    1 
ATOM   4554 C  CE    . LYS B 1 283 ? 112.892 71.636  83.284  1.00 21.72 ? 283 LYS B CE    1 
ATOM   4555 N  NZ    . LYS B 1 283 ? 112.861 71.836  81.830  1.00 21.72 ? 283 LYS B NZ    1 
ATOM   4556 N  N     . VAL B 1 284 ? 115.240 70.651  88.820  1.00 26.37 ? 284 VAL B N     1 
ATOM   4557 C  CA    . VAL B 1 284 ? 115.799 69.496  89.521  1.00 26.37 ? 284 VAL B CA    1 
ATOM   4558 C  C     . VAL B 1 284 ? 115.156 69.315  90.896  1.00 26.37 ? 284 VAL B C     1 
ATOM   4559 O  O     . VAL B 1 284 ? 114.838 68.192  91.307  1.00 26.37 ? 284 VAL B O     1 
ATOM   4560 C  CB    . VAL B 1 284 ? 117.324 69.661  89.632  1.00 26.37 ? 284 VAL B CB    1 
ATOM   4561 C  CG1   . VAL B 1 284 ? 117.929 68.585  90.524  1.00 26.37 ? 284 VAL B CG1   1 
ATOM   4562 C  CG2   . VAL B 1 284 ? 117.954 69.658  88.268  1.00 26.37 ? 284 VAL B CG2   1 
ATOM   4563 N  N     . PHE B 1 285 ? 114.919 70.411  91.612  1.00 25.21 ? 285 PHE B N     1 
ATOM   4564 C  CA    . PHE B 1 285 ? 114.222 70.335  92.890  1.00 25.21 ? 285 PHE B CA    1 
ATOM   4565 C  C     . PHE B 1 285 ? 112.802 69.808  92.738  1.00 25.21 ? 285 PHE B C     1 
ATOM   4566 O  O     . PHE B 1 285 ? 112.351 69.011  93.557  1.00 25.21 ? 285 PHE B O     1 
ATOM   4567 C  CB    . PHE B 1 285 ? 114.221 71.691  93.584  1.00 25.21 ? 285 PHE B CB    1 
ATOM   4568 C  CG    . PHE B 1 285 ? 113.458 71.690  94.865  1.00 25.21 ? 285 PHE B CG    1 
ATOM   4569 C  CD1   . PHE B 1 285 ? 113.887 70.933  95.937  1.00 25.21 ? 285 PHE B CD1   1 
ATOM   4570 C  CD2   . PHE B 1 285 ? 112.305 72.452  94.998  1.00 25.21 ? 285 PHE B CD2   1 
ATOM   4571 C  CE1   . PHE B 1 285 ? 113.175 70.908  97.096  1.00 25.21 ? 285 PHE B CE1   1 
ATOM   4572 C  CE2   . PHE B 1 285 ? 111.593 72.432  96.169  1.00 25.21 ? 285 PHE B CE2   1 
ATOM   4573 C  CZ    . PHE B 1 285 ? 112.029 71.663  97.215  1.00 25.21 ? 285 PHE B CZ    1 
ATOM   4574 N  N     . LEU B 1 286 ? 112.060 70.281  91.733  1.00 24.95 ? 286 LEU B N     1 
ATOM   4575 C  CA    . LEU B 1 286 ? 110.729 69.735  91.481  1.00 24.95 ? 286 LEU B CA    1 
ATOM   4576 C  C     . LEU B 1 286 ? 110.789 68.269  91.095  1.00 24.95 ? 286 LEU B C     1 
ATOM   4577 O  O     . LEU B 1 286 ? 109.893 67.506  91.447  1.00 24.95 ? 286 LEU B O     1 
ATOM   4578 C  CB    . LEU B 1 286 ? 109.994 70.522  90.403  1.00 24.95 ? 286 LEU B CB    1 
ATOM   4579 C  CG    . LEU B 1 286 ? 109.458 71.894  90.759  1.00 24.95 ? 286 LEU B CG    1 
ATOM   4580 C  CD1   . LEU B 1 286 ? 108.828 72.534  89.562  1.00 24.95 ? 286 LEU B CD1   1 
ATOM   4581 C  CD2   . LEU B 1 286 ? 108.435 71.712  91.832  1.00 24.95 ? 286 LEU B CD2   1 
ATOM   4582 N  N     . GLN B 1 287 ? 111.815 67.857  90.358  1.00 29.05 ? 287 GLN B N     1 
ATOM   4583 C  CA    . GLN B 1 287 ? 111.981 66.437  90.081  1.00 29.05 ? 287 GLN B CA    1 
ATOM   4584 C  C     . GLN B 1 287 ? 112.156 65.637  91.370  1.00 29.05 ? 287 GLN B C     1 
ATOM   4585 O  O     . GLN B 1 287 ? 111.519 64.595  91.550  1.00 29.05 ? 287 GLN B O     1 
ATOM   4586 C  CB    . GLN B 1 287 ? 113.156 66.222  89.135  1.00 29.05 ? 287 GLN B CB    1 
ATOM   4587 C  CG    . GLN B 1 287 ? 113.398 64.775  88.768  1.00 29.05 ? 287 GLN B CG    1 
ATOM   4588 C  CD    . GLN B 1 287 ? 114.865 64.418  88.862  1.00 29.05 ? 287 GLN B CD    1 
ATOM   4589 O  OE1   . GLN B 1 287 ? 115.726 65.172  88.408  1.00 29.05 ? 287 GLN B OE1   1 
ATOM   4590 N  NE2   . GLN B 1 287 ? 115.162 63.297  89.498  1.00 29.05 ? 287 GLN B NE2   1 
ATOM   4591 N  N     . HIS B 1 288 ? 112.970 66.135  92.301  1.00 32.77 ? 288 HIS B N     1 
ATOM   4592 C  CA    . HIS B 1 288 ? 113.134 65.446  93.581  1.00 32.77 ? 288 HIS B CA    1 
ATOM   4593 C  C     . HIS B 1 288 ? 111.855 65.493  94.406  1.00 32.77 ? 288 HIS B C     1 
ATOM   4594 O  O     . HIS B 1 288 ? 111.500 64.502  95.049  1.00 32.77 ? 288 HIS B O     1 
ATOM   4595 C  CB    . HIS B 1 288 ? 114.287 66.050  94.381  1.00 32.77 ? 288 HIS B CB    1 
ATOM   4596 C  CG    . HIS B 1 288 ? 115.626 65.888  93.738  1.00 32.77 ? 288 HIS B CG    1 
ATOM   4597 N  ND1   . HIS B 1 288 ? 116.742 66.566  94.172  1.00 32.77 ? 288 HIS B ND1   1 
ATOM   4598 C  CD2   . HIS B 1 288 ? 116.044 65.070  92.748  1.00 32.77 ? 288 HIS B CD2   1 
ATOM   4599 C  CE1   . HIS B 1 288 ? 117.778 66.215  93.437  1.00 32.77 ? 288 HIS B CE1   1 
ATOM   4600 N  NE2   . HIS B 1 288 ? 117.383 65.303  92.570  1.00 32.77 ? 288 HIS B NE2   1 
ATOM   4601 N  N     . TYR B 1 289 ? 111.165 66.638  94.425  1.00 29.80 ? 289 TYR B N     1 
ATOM   4602 C  CA    . TYR B 1 289 ? 109.899 66.740  95.144  1.00 29.80 ? 289 TYR B CA    1 
ATOM   4603 C  C     . TYR B 1 289 ? 108.883 65.755  94.602  1.00 29.80 ? 289 TYR B C     1 
ATOM   4604 O  O     . TYR B 1 289 ? 108.223 65.049  95.367  1.00 29.80 ? 289 TYR B O     1 
ATOM   4605 C  CB    . TYR B 1 289 ? 109.330 68.151  95.052  1.00 29.80 ? 289 TYR B CB    1 
ATOM   4606 C  CG    . TYR B 1 289 ? 107.972 68.228  95.695  1.00 29.80 ? 289 TYR B CG    1 
ATOM   4607 C  CD1   . TYR B 1 289 ? 107.815 68.069  97.058  1.00 29.80 ? 289 TYR B CD1   1 
ATOM   4608 C  CD2   . TYR B 1 289 ? 106.831 68.385  94.924  1.00 29.80 ? 289 TYR B CD2   1 
ATOM   4609 C  CE1   . TYR B 1 289 ? 106.573 68.144  97.643  1.00 29.80 ? 289 TYR B CE1   1 
ATOM   4610 C  CE2   . TYR B 1 289 ? 105.584 68.420  95.503  1.00 29.80 ? 289 TYR B CE2   1 
ATOM   4611 C  CZ    . TYR B 1 289 ? 105.464 68.308  96.862  1.00 29.80 ? 289 TYR B CZ    1 
ATOM   4612 O  OH    . TYR B 1 289 ? 104.220 68.322  97.432  1.00 29.80 ? 289 TYR B OH    1 
ATOM   4613 N  N     . TRP B 1 290 ? 108.799 65.654  93.280  1.00 32.58 ? 290 TRP B N     1 
ATOM   4614 C  CA    . TRP B 1 290 ? 107.933 64.692  92.630  1.00 32.58 ? 290 TRP B CA    1 
ATOM   4615 C  C     . TRP B 1 290 ? 108.297 63.290  93.074  1.00 32.58 ? 290 TRP B C     1 
ATOM   4616 O  O     . TRP B 1 290 ? 107.439 62.540  93.537  1.00 32.58 ? 290 TRP B O     1 
ATOM   4617 C  CB    . TRP B 1 290 ? 108.067 64.842  91.111  1.00 32.58 ? 290 TRP B CB    1 
ATOM   4618 C  CG    . TRP B 1 290 ? 107.142 63.998  90.254  1.00 32.58 ? 290 TRP B CG    1 
ATOM   4619 C  CD1   . TRP B 1 290 ? 105.916 64.360  89.775  1.00 32.58 ? 290 TRP B CD1   1 
ATOM   4620 C  CD2   . TRP B 1 290 ? 107.382 62.676  89.766  1.00 32.58 ? 290 TRP B CD2   1 
ATOM   4621 N  NE1   . TRP B 1 290 ? 105.379 63.347  89.036  1.00 32.58 ? 290 TRP B NE1   1 
ATOM   4622 C  CE2   . TRP B 1 290 ? 106.258 62.298  89.018  1.00 32.58 ? 290 TRP B CE2   1 
ATOM   4623 C  CE3   . TRP B 1 290 ? 108.433 61.770  89.901  1.00 32.58 ? 290 TRP B CE3   1 
ATOM   4624 C  CZ2   . TRP B 1 290 ? 106.161 61.064  88.405  1.00 32.58 ? 290 TRP B CZ2   1 
ATOM   4625 C  CZ3   . TRP B 1 290 ? 108.333 60.552  89.295  1.00 32.58 ? 290 TRP B CZ3   1 
ATOM   4626 C  CH2   . TRP B 1 290 ? 107.208 60.206  88.554  1.00 32.58 ? 290 TRP B CH2   1 
ATOM   4627 N  N     . VAL B 1 291 ? 109.568 62.912  92.918  1.00 35.71 ? 291 VAL B N     1 
ATOM   4628 C  CA    . VAL B 1 291 ? 110.032 61.571  93.294  1.00 35.71 ? 291 VAL B CA    1 
ATOM   4629 C  C     . VAL B 1 291 ? 109.701 61.230  94.748  1.00 35.71 ? 291 VAL B C     1 
ATOM   4630 O  O     . VAL B 1 291 ? 109.133 60.171  95.043  1.00 35.71 ? 291 VAL B O     1 
ATOM   4631 C  CB    . VAL B 1 291 ? 111.540 61.433  93.016  1.00 35.71 ? 291 VAL B CB    1 
ATOM   4632 C  CG1   . VAL B 1 291 ? 112.095 60.216  93.701  1.00 35.71 ? 291 VAL B CG1   1 
ATOM   4633 C  CG2   . VAL B 1 291 ? 111.795 61.346  91.527  1.00 35.71 ? 291 VAL B CG2   1 
ATOM   4634 N  N     . VAL B 1 292 ? 110.069 62.106  95.680  1.00 37.69 ? 292 VAL B N     1 
ATOM   4635 C  CA    . VAL B 1 292 ? 109.811 61.859  97.099  1.00 37.69 ? 292 VAL B CA    1 
ATOM   4636 C  C     . VAL B 1 292 ? 108.315 61.783  97.400  1.00 37.69 ? 292 VAL B C     1 
ATOM   4637 O  O     . VAL B 1 292 ? 107.876 60.909  98.155  1.00 37.69 ? 292 VAL B O     1 
ATOM   4638 C  CB    . VAL B 1 292 ? 110.512 62.925  97.958  1.00 37.69 ? 292 VAL B CB    1 
ATOM   4639 C  CG1   . VAL B 1 292 ? 110.169 62.736  99.405  1.00 37.69 ? 292 VAL B CG1   1 
ATOM   4640 C  CG2   . VAL B 1 292 ? 112.006 62.850  97.763  1.00 37.69 ? 292 VAL B CG2   1 
ATOM   4641 N  N     . SER B 1 293 ? 107.506 62.683  96.826  1.00 37.56 ? 293 SER B N     1 
ATOM   4642 C  CA    . SER B 1 293 ? 106.063 62.646  97.063  1.00 37.56 ? 293 SER B CA    1 
ATOM   4643 C  C     . SER B 1 293 ? 105.429 61.387  96.486  1.00 37.56 ? 293 SER B C     1 
ATOM   4644 O  O     . SER B 1 293 ? 104.500 60.826  97.078  1.00 37.56 ? 293 SER B O     1 
ATOM   4645 C  CB    . SER B 1 293 ? 105.387 63.887  96.483  1.00 37.56 ? 293 SER B CB    1 
ATOM   4646 O  OG    . SER B 1 293 ? 105.921 65.070  97.018  1.00 37.56 ? 293 SER B OG    1 
ATOM   4647 N  N     . ARG B 1 294 ? 105.902 60.944  95.322  1.00 41.45 ? 294 ARG B N     1 
ATOM   4648 C  CA    . ARG B 1 294 ? 105.422 59.700  94.734  1.00 41.45 ? 294 ARG B CA    1 
ATOM   4649 C  C     . ARG B 1 294 ? 105.757 58.513  95.620  1.00 41.45 ? 294 ARG B C     1 
ATOM   4650 O  O     . ARG B 1 294 ? 104.901 57.657  95.861  1.00 41.45 ? 294 ARG B O     1 
ATOM   4651 C  CB    . ARG B 1 294 ? 106.040 59.503  93.349  1.00 41.45 ? 294 ARG B CB    1 
ATOM   4652 C  CG    . ARG B 1 294 ? 105.631 60.520  92.297  1.00 41.45 ? 294 ARG B CG    1 
ATOM   4653 C  CD    . ARG B 1 294 ? 104.287 60.310  91.669  1.00 41.45 ? 294 ARG B CD    1 
ATOM   4654 N  NE    . ARG B 1 294 ? 104.311 59.195  90.736  1.00 41.45 ? 294 ARG B NE    1 
ATOM   4655 C  CZ    . ARG B 1 294 ? 103.339 58.920  89.878  1.00 41.45 ? 294 ARG B CZ    1 
ATOM   4656 N  NH1   . ARG B 1 294 ? 102.261 59.677  89.791  1.00 41.45 ? 294 ARG B NH1   1 
ATOM   4657 N  NH2   . ARG B 1 294 ? 103.465 57.874  89.072  1.00 41.45 ? 294 ARG B NH2   1 
ATOM   4658 N  N     . GLU B 1 295 ? 106.998 58.436  96.122  1.00 47.25 ? 295 GLU B N     1 
ATOM   4659 C  CA    . GLU B 1 295 ? 107.357 57.302  96.984  1.00 47.25 ? 295 GLU B CA    1 
ATOM   4660 C  C     . GLU B 1 295 ? 106.626 57.339  98.319  1.00 47.25 ? 295 GLU B C     1 
ATOM   4661 O  O     . GLU B 1 295 ? 106.203 56.294  98.826  1.00 47.25 ? 295 GLU B O     1 
ATOM   4662 C  CB    . GLU B 1 295 ? 108.866 57.229  97.218  1.00 47.25 ? 295 GLU B CB    1 
ATOM   4663 C  CG    . GLU B 1 295 ? 109.644 56.732  96.014  1.00 47.25 ? 295 GLU B CG    1 
ATOM   4664 C  CD    . GLU B 1 295 ? 111.131 56.612  96.278  1.00 47.25 ? 295 GLU B CD    1 
ATOM   4665 O  OE1   . GLU B 1 295 ? 111.524 56.571  97.460  1.00 47.25 ? 295 GLU B OE1   1 
ATOM   4666 O  OE2   . GLU B 1 295 ? 111.904 56.536  95.299  1.00 47.25 ? 295 GLU B OE2   1 
ATOM   4667 N  N     . LEU B 1 296 ? 106.455 58.528  98.901  1.00 45.71 ? 296 LEU B N     1 
ATOM   4668 C  CA    . LEU B 1 296 ? 105.722 58.628  100.156 1.00 45.71 ? 296 LEU B CA    1 
ATOM   4669 C  C     . LEU B 1 296 ? 104.285 58.175  99.966  1.00 45.71 ? 296 LEU B C     1 
ATOM   4670 O  O     . LEU B 1 296 ? 103.764 57.367  100.748 1.00 45.71 ? 296 LEU B O     1 
ATOM   4671 C  CB    . LEU B 1 296 ? 105.791 60.052  100.693 1.00 45.71 ? 296 LEU B CB    1 
ATOM   4672 C  CG    . LEU B 1 296 ? 107.139 60.308  101.366 1.00 45.71 ? 296 LEU B CG    1 
ATOM   4673 C  CD1   . LEU B 1 296 ? 107.331 61.758  101.632 1.00 45.71 ? 296 LEU B CD1   1 
ATOM   4674 C  CD2   . LEU B 1 296 ? 107.231 59.519  102.647 1.00 45.71 ? 296 LEU B CD2   1 
ATOM   4675 N  N     . ALA B 1 297 ? 103.640 58.651  98.902  1.00 48.02 ? 297 ALA B N     1 
ATOM   4676 C  CA    . ALA B 1 297 ? 102.265 58.258  98.640  1.00 48.02 ? 297 ALA B CA    1 
ATOM   4677 C  C     . ALA B 1 297 ? 102.144 56.849  98.065  1.00 48.02 ? 297 ALA B C     1 
ATOM   4678 O  O     . ALA B 1 297 ? 101.030 56.321  97.998  1.00 48.02 ? 297 ALA B O     1 
ATOM   4679 C  CB    . ALA B 1 297 ? 101.606 59.271  97.707  1.00 48.02 ? 297 ALA B CB    1 
ATOM   4680 N  N     . GLY B 1 298 ? 103.248 56.228  97.653  1.00 50.51 ? 298 GLY B N     1 
ATOM   4681 C  CA    . GLY B 1 298 ? 103.211 54.865  97.145  1.00 50.51 ? 298 GLY B CA    1 
ATOM   4682 C  C     . GLY B 1 298 ? 102.834 54.714  95.688  1.00 50.51 ? 298 GLY B C     1 
ATOM   4683 O  O     . GLY B 1 298 ? 102.149 53.756  95.328  1.00 50.51 ? 298 GLY B O     1 
ATOM   4684 N  N     . PHE B 1 299 ? 103.235 55.658  94.845  1.00 50.17 ? 299 PHE B N     1 
ATOM   4685 C  CA    . PHE B 1 299 ? 102.997 55.641  93.410  1.00 50.17 ? 299 PHE B CA    1 
ATOM   4686 C  C     . PHE B 1 299 ? 104.254 55.163  92.680  1.00 50.17 ? 299 PHE B C     1 
ATOM   4687 O  O     . PHE B 1 299 ? 105.326 55.019  93.270  1.00 50.17 ? 299 PHE B O     1 
ATOM   4688 C  CB    . PHE B 1 299 ? 102.524 57.016  92.927  1.00 50.17 ? 299 PHE B CB    1 
ATOM   4689 C  CG    . PHE B 1 299 ? 101.271 57.481  93.607  1.00 50.17 ? 299 PHE B CG    1 
ATOM   4690 C  CD1   . PHE B 1 299 ? 100.165 56.648  93.689  1.00 50.17 ? 299 PHE B CD1   1 
ATOM   4691 C  CD2   . PHE B 1 299 ? 101.187 58.742  94.162  1.00 50.17 ? 299 PHE B CD2   1 
ATOM   4692 C  CE1   . PHE B 1 299 ? 99.009  57.058  94.320  1.00 50.17 ? 299 PHE B CE1   1 
ATOM   4693 C  CE2   . PHE B 1 299 ? 100.025 59.160  94.788  1.00 50.17 ? 299 PHE B CE2   1 
ATOM   4694 C  CZ    . PHE B 1 299 ? 98.940  58.314  94.875  1.00 50.17 ? 299 PHE B CZ    1 
ATOM   4695 N  N     . SER B 1 300 ? 104.099 54.884  91.389  1.00 52.46 ? 300 SER B N     1 
ATOM   4696 C  CA    . SER B 1 300 ? 105.189 54.353  90.571  1.00 52.46 ? 300 SER B CA    1 
ATOM   4697 C  C     . SER B 1 300 ? 106.315 55.363  90.355  1.00 52.46 ? 300 SER B C     1 
ATOM   4698 O  O     . SER B 1 300 ? 106.084 56.569  90.269  1.00 52.46 ? 300 SER B O     1 
ATOM   4699 C  CB    . SER B 1 300 ? 104.644 53.882  89.221  1.00 52.46 ? 300 SER B CB    1 
ATOM   4700 O  OG    . SER B 1 300 ? 105.629 53.174  88.494  1.00 52.46 ? 300 SER B OG    1 
ATOM   4701 N  N     . VAL B 1 301 ? 107.552 54.857  90.315  1.00 50.76 ? 301 VAL B N     1 
ATOM   4702 C  CA    . VAL B 1 301 ? 108.747 55.675  90.132  1.00 50.76 ? 301 VAL B CA    1 
ATOM   4703 C  C     . VAL B 1 301 ? 109.165 55.704  88.664  1.00 50.76 ? 301 VAL B C     1 
ATOM   4704 O  O     . VAL B 1 301 ? 108.743 54.885  87.847  1.00 50.76 ? 301 VAL B O     1 
ATOM   4705 C  CB    . VAL B 1 301 ? 109.903 55.176  91.027  1.00 50.76 ? 301 VAL B CB    1 
ATOM   4706 C  CG1   . VAL B 1 301 ? 109.534 55.318  92.494  1.00 50.76 ? 301 VAL B CG1   1 
ATOM   4707 C  CG2   . VAL B 1 301 ? 110.232 53.721  90.706  1.00 50.76 ? 301 VAL B CG2   1 
ATOM   4708 N  N     . SER B 1 302 ? 109.999 56.686  88.326  1.00 45.35 ? 302 SER B N     1 
ATOM   4709 C  CA    . SER B 1 302 ? 110.498 56.907  86.971  1.00 45.35 ? 302 SER B CA    1 
ATOM   4710 C  C     . SER B 1 302 ? 111.751 57.773  87.066  1.00 45.35 ? 302 SER B C     1 
ATOM   4711 O  O     . SER B 1 302 ? 112.224 58.092  88.160  1.00 45.35 ? 302 SER B O     1 
ATOM   4712 C  CB    . SER B 1 302 ? 109.416 57.555  86.099  1.00 45.35 ? 302 SER B CB    1 
ATOM   4713 O  OG    . SER B 1 302 ? 109.861 57.814  84.779  1.00 45.35 ? 302 SER B OG    1 
ATOM   4714 N  N     . LYS B 1 303 ? 112.296 58.151  85.913  1.00 41.46 ? 303 LYS B N     1 
ATOM   4715 C  CA    . LYS B 1 303 ? 113.303 59.206  85.897  1.00 41.46 ? 303 LYS B CA    1 
ATOM   4716 C  C     . LYS B 1 303 ? 113.298 60.011  84.602  1.00 41.46 ? 303 LYS B C     1 
ATOM   4717 O  O     . LYS B 1 303 ? 113.820 61.124  84.562  1.00 41.46 ? 303 LYS B O     1 
ATOM   4718 C  CB    . LYS B 1 303 ? 114.695 58.632  86.157  1.00 41.46 ? 303 LYS B CB    1 
ATOM   4719 C  CG    . LYS B 1 303 ? 115.221 57.660  85.120  1.00 41.46 ? 303 LYS B CG    1 
ATOM   4720 C  CD    . LYS B 1 303 ? 116.651 57.254  85.452  1.00 41.46 ? 303 LYS B CD    1 
ATOM   4721 C  CE    . LYS B 1 303 ? 117.194 56.252  84.445  1.00 41.46 ? 303 LYS B CE    1 
ATOM   4722 N  NZ    . LYS B 1 303 ? 118.626 55.937  84.697  1.00 41.46 ? 303 LYS B NZ    1 
ATOM   4723 N  N     . ILE B 1 316 ? 121.009 63.030  89.366  1.00 43.29 ? 316 ILE B N     1 
ATOM   4724 C  CA    . ILE B 1 316 ? 121.110 63.586  90.708  1.00 43.29 ? 316 ILE B CA    1 
ATOM   4725 C  C     . ILE B 1 316 ? 120.041 62.973  91.609  1.00 43.29 ? 316 ILE B C     1 
ATOM   4726 O  O     . ILE B 1 316 ? 118.870 63.004  91.274  1.00 43.29 ? 316 ILE B O     1 
ATOM   4727 C  CB    . ILE B 1 316 ? 120.975 65.100  90.674  1.00 43.29 ? 316 ILE B CB    1 
ATOM   4728 C  CG1   . ILE B 1 316 ? 121.925 65.701  89.642  1.00 43.29 ? 316 ILE B CG1   1 
ATOM   4729 C  CG2   . ILE B 1 316 ? 121.274 65.670  92.032  1.00 43.29 ? 316 ILE B CG2   1 
ATOM   4730 C  CD1   . ILE B 1 316 ? 121.771 67.192  89.481  1.00 43.29 ? 316 ILE B CD1   1 
ATOM   4731 N  N     . LYS B 1 317 ? 120.444 62.368  92.722  1.00 46.34 ? 317 LYS B N     1 
ATOM   4732 C  CA    . LYS B 1 317 ? 119.565 61.821  93.751  1.00 46.34 ? 317 LYS B CA    1 
ATOM   4733 C  C     . LYS B 1 317 ? 119.260 62.887  94.801  1.00 46.34 ? 317 LYS B C     1 
ATOM   4734 O  O     . LYS B 1 317 ? 120.117 63.726  95.084  1.00 46.34 ? 317 LYS B O     1 
ATOM   4735 C  CB    . LYS B 1 317 ? 120.219 60.618  94.424  1.00 46.34 ? 317 LYS B CB    1 
ATOM   4736 C  CG    . LYS B 1 317 ? 119.935 59.276  93.744  1.00 46.34 ? 317 LYS B CG    1 
ATOM   4737 C  CD    . LYS B 1 317 ? 118.562 58.696  94.059  1.00 46.34 ? 317 LYS B CD    1 
ATOM   4738 C  CE    . LYS B 1 317 ? 118.405 58.339  95.530  1.00 46.34 ? 317 LYS B CE    1 
ATOM   4739 N  NZ    . LYS B 1 317 ? 117.141 57.588  95.765  1.00 46.34 ? 317 LYS B NZ    1 
ATOM   4740 N  N     . PRO B 1 318 ? 118.055 62.928  95.374  1.00 44.64 ? 318 PRO B N     1 
ATOM   4741 C  CA    . PRO B 1 318 ? 117.778 63.915  96.417  1.00 44.64 ? 318 PRO B CA    1 
ATOM   4742 C  C     . PRO B 1 318 ? 118.762 63.773  97.559  1.00 44.64 ? 318 PRO B C     1 
ATOM   4743 O  O     . PRO B 1 318 ? 119.250 62.664  97.846  1.00 44.64 ? 318 PRO B O     1 
ATOM   4744 C  CB    . PRO B 1 318 ? 116.345 63.579  96.853  1.00 44.64 ? 318 PRO B CB    1 
ATOM   4745 C  CG    . PRO B 1 318 ? 115.775 62.800  95.755  1.00 44.64 ? 318 PRO B CG    1 
ATOM   4746 C  CD    . PRO B 1 318 ? 116.907 62.045  95.140  1.00 44.64 ? 318 PRO B CD    1 
ATOM   4747 N  N     . PRO B 1 319 ? 119.060 64.862  98.265  1.00 46.29 ? 319 PRO B N     1 
ATOM   4748 C  CA    . PRO B 1 319 ? 120.098 64.800  99.303  1.00 46.29 ? 319 PRO B CA    1 
ATOM   4749 C  C     . PRO B 1 319 ? 119.796 64.002  100.565 1.00 46.29 ? 319 PRO B C     1 
ATOM   4750 O  O     . PRO B 1 319 ? 120.542 63.083  100.917 1.00 46.29 ? 319 PRO B O     1 
ATOM   4751 C  CB    . PRO B 1 319 ? 120.324 66.278  99.648  1.00 46.29 ? 319 PRO B CB    1 
ATOM   4752 C  CG    . PRO B 1 319 ? 119.116 66.969  99.219  1.00 46.29 ? 319 PRO B CG    1 
ATOM   4753 C  CD    . PRO B 1 319 ? 118.588 66.234  98.043  1.00 46.29 ? 319 PRO B CD    1 
ATOM   4754 N  N     . HIS B 1 320 ? 118.733 64.363  101.262 1.00 46.99 ? 320 HIS B N     1 
ATOM   4755 C  CA    . HIS B 1 320 ? 118.368 63.772  102.540 1.00 46.99 ? 320 HIS B CA    1 
ATOM   4756 C  C     . HIS B 1 320 ? 117.475 62.540  102.452 1.00 46.99 ? 320 HIS B C     1 
ATOM   4757 O  O     . HIS B 1 320 ? 117.180 61.941  103.487 1.00 46.99 ? 320 HIS B O     1 
ATOM   4758 C  CB    . HIS B 1 320 ? 117.764 64.868  103.414 1.00 46.99 ? 320 HIS B CB    1 
ATOM   4759 C  CG    . HIS B 1 320 ? 118.772 65.902  103.804 1.00 46.99 ? 320 HIS B CG    1 
ATOM   4760 N  ND1   . HIS B 1 320 ? 119.715 65.685  104.783 1.00 46.99 ? 320 HIS B ND1   1 
ATOM   4761 C  CD2   . HIS B 1 320 ? 119.061 67.109  103.269 1.00 46.99 ? 320 HIS B CD2   1 
ATOM   4762 C  CE1   . HIS B 1 320 ? 120.500 66.741  104.879 1.00 46.99 ? 320 HIS B CE1   1 
ATOM   4763 N  NE2   . HIS B 1 320 ? 120.128 67.617  103.966 1.00 46.99 ? 320 HIS B NE2   1 
ATOM   4764 N  N     . TRP B 1 321 ? 117.019 62.161  101.270 1.00 50.28 ? 321 TRP B N     1 
ATOM   4765 C  CA    . TRP B 1 321 ? 116.096 61.044  101.120 1.00 50.28 ? 321 TRP B CA    1 
ATOM   4766 C  C     . TRP B 1 321 ? 116.826 59.723  100.926 1.00 50.28 ? 321 TRP B C     1 
ATOM   4767 O  O     . TRP B 1 321 ? 117.704 59.602  100.069 1.00 50.28 ? 321 TRP B O     1 
ATOM   4768 C  CB    . TRP B 1 321 ? 115.127 61.320  99.974  1.00 50.28 ? 321 TRP B CB    1 
ATOM   4769 C  CG    . TRP B 1 321 ? 114.076 60.278  99.795  1.00 50.28 ? 321 TRP B CG    1 
ATOM   4770 C  CD1   . TRP B 1 321 ? 114.025 59.329  98.828  1.00 50.28 ? 321 TRP B CD1   1 
ATOM   4771 C  CD2   . TRP B 1 321 ? 113.013 59.978  100.704 1.00 50.28 ? 321 TRP B CD2   1 
ATOM   4772 N  NE1   . TRP B 1 321 ? 112.930 58.527  99.011  1.00 50.28 ? 321 TRP B NE1   1 
ATOM   4773 C  CE2   . TRP B 1 321 ? 112.300 58.899  100.167 1.00 50.28 ? 321 TRP B CE2   1 
ATOM   4774 C  CE3   . TRP B 1 321 ? 112.569 60.550  101.896 1.00 50.28 ? 321 TRP B CE3   1 
ATOM   4775 C  CZ2   . TRP B 1 321 ? 111.177 58.373  100.782 1.00 50.28 ? 321 TRP B CZ2   1 
ATOM   4776 C  CZ3   . TRP B 1 321 ? 111.456 60.028  102.502 1.00 50.28 ? 321 TRP B CZ3   1 
ATOM   4777 C  CH2   . TRP B 1 321 ? 110.769 58.954  101.946 1.00 50.28 ? 321 TRP B CH2   1 
ATOM   4778 N  N     . ASN B 1 322 ? 116.465 58.745  101.754 1.00 57.64 ? 322 ASN B N     1 
ATOM   4779 C  CA    . ASN B 1 322 ? 117.088 57.428  101.770 1.00 57.64 ? 322 ASN B CA    1 
ATOM   4780 C  C     . ASN B 1 322 ? 116.053 56.328  102.005 1.00 57.64 ? 322 ASN B C     1 
ATOM   4781 O  O     . ASN B 1 322 ? 115.322 56.344  102.997 1.00 57.64 ? 322 ASN B O     1 
ATOM   4782 C  CB    . ASN B 1 322 ? 118.145 57.373  102.876 1.00 57.64 ? 322 ASN B CB    1 
ATOM   4783 C  CG    . ASN B 1 322 ? 119.426 58.069  102.489 1.00 57.64 ? 322 ASN B CG    1 
ATOM   4784 O  OD1   . ASN B 1 322 ? 119.910 57.921  101.368 1.00 57.64 ? 322 ASN B OD1   1 
ATOM   4785 N  ND2   . ASN B 1 322 ? 119.970 58.862  103.406 1.00 57.64 ? 322 ASN B ND2   1 
ATOM   4786 O  "O5'" . A   C 2 1   ? 119.855 64.135  86.182  1.00 34.32 ? 1   A   C "O5'" 1 
ATOM   4787 C  "C5'" . A   C 2 1   ? 120.146 64.983  85.081  1.00 34.32 ? 1   A   C "C5'" 1 
ATOM   4788 C  "C4'" . A   C 2 1   ? 120.686 64.214  83.897  1.00 34.32 ? 1   A   C "C4'" 1 
ATOM   4789 O  "O4'" . A   C 2 1   ? 119.746 63.205  83.465  1.00 34.32 ? 1   A   C "O4'" 1 
ATOM   4790 C  "C3'" . A   C 2 1   ? 120.916 65.015  82.630  1.00 34.32 ? 1   A   C "C3'" 1 
ATOM   4791 O  "O3'" . A   C 2 1   ? 122.089 65.798  82.691  1.00 34.32 ? 1   A   C "O3'" 1 
ATOM   4792 C  "C2'" . A   C 2 1   ? 121.020 63.914  81.577  1.00 34.32 ? 1   A   C "C2'" 1 
ATOM   4793 O  "O2'" . A   C 2 1   ? 122.321 63.349  81.568  1.00 34.32 ? 1   A   C "O2'" 1 
ATOM   4794 C  "C1'" . A   C 2 1   ? 120.032 62.869  82.119  1.00 34.32 ? 1   A   C "C1'" 1 
ATOM   4795 N  N9    . A   C 2 1   ? 118.784 62.792  81.330  1.00 34.32 ? 1   A   C N9    1 
ATOM   4796 C  C8    . A   C 2 1   ? 118.234 63.699  80.464  1.00 34.32 ? 1   A   C C8    1 
ATOM   4797 N  N7    . A   C 2 1   ? 117.112 63.290  79.920  1.00 34.32 ? 1   A   C N7    1 
ATOM   4798 C  C5    . A   C 2 1   ? 116.919 62.027  80.452  1.00 34.32 ? 1   A   C C5    1 
ATOM   4799 C  C6    . A   C 2 1   ? 115.919 61.054  80.290  1.00 34.32 ? 1   A   C C6    1 
ATOM   4800 N  N6    . A   C 2 1   ? 114.853 61.179  79.509  1.00 34.32 ? 1   A   C N6    1 
ATOM   4801 N  N1    . A   C 2 1   ? 116.047 59.907  80.981  1.00 34.32 ? 1   A   C N1    1 
ATOM   4802 C  C2    . A   C 2 1   ? 117.103 59.739  81.774  1.00 34.32 ? 1   A   C C2    1 
ATOM   4803 N  N3    . A   C 2 1   ? 118.103 60.571  82.013  1.00 34.32 ? 1   A   C N3    1 
ATOM   4804 C  C4    . A   C 2 1   ? 117.946 61.708  81.316  1.00 34.32 ? 1   A   C C4    1 
ATOM   4805 P  P     . G   C 2 2   ? 122.094 67.279  82.092  1.00 32.98 ? 2   G   C P     1 
ATOM   4806 O  OP1   . G   C 2 2   ? 123.402 67.895  82.411  1.00 32.98 ? 2   G   C OP1   1 
ATOM   4807 O  OP2   . G   C 2 2   ? 120.854 67.931  82.555  1.00 32.98 ? 2   G   C OP2   1 
ATOM   4808 O  "O5'" . G   C 2 2   ? 121.980 67.107  80.510  1.00 32.98 ? 2   G   C "O5'" 1 
ATOM   4809 C  "C5'" . G   C 2 2   ? 121.708 68.265  79.738  1.00 32.98 ? 2   G   C "C5'" 1 
ATOM   4810 C  "C4'" . G   C 2 2   ? 121.485 68.038  78.263  1.00 32.98 ? 2   G   C "C4'" 1 
ATOM   4811 O  "O4'" . G   C 2 2   ? 120.666 66.873  77.996  1.00 32.98 ? 2   G   C "O4'" 1 
ATOM   4812 C  "C3'" . G   C 2 2   ? 120.779 69.209  77.592  1.00 32.98 ? 2   G   C "C3'" 1 
ATOM   4813 O  "O3'" . G   C 2 2   ? 121.703 70.070  76.982  1.00 32.98 ? 2   G   C "O3'" 1 
ATOM   4814 C  "C2'" . G   C 2 2   ? 119.817 68.587  76.592  1.00 32.98 ? 2   G   C "C2'" 1 
ATOM   4815 O  "O2'" . G   C 2 2   ? 120.439 68.417  75.328  1.00 32.98 ? 2   G   C "O2'" 1 
ATOM   4816 C  "C1'" . G   C 2 2   ? 119.552 67.224  77.210  1.00 32.98 ? 2   G   C "C1'" 1 
ATOM   4817 N  N9    . G   C 2 2   ? 118.312 67.019  77.987  1.00 32.98 ? 2   G   C N9    1 
ATOM   4818 C  C8    . G   C 2 2   ? 118.301 66.834  79.342  1.00 32.98 ? 2   G   C C8    1 
ATOM   4819 N  N7    . G   C 2 2   ? 117.127 66.563  79.819  1.00 32.98 ? 2   G   C N7    1 
ATOM   4820 C  C5    . G   C 2 2   ? 116.315 66.489  78.705  1.00 32.98 ? 2   G   C C5    1 
ATOM   4821 C  C6    . G   C 2 2   ? 114.927 66.211  78.627  1.00 32.98 ? 2   G   C C6    1 
ATOM   4822 O  O6    . G   C 2 2   ? 114.152 65.992  79.563  1.00 32.98 ? 2   G   C O6    1 
ATOM   4823 N  N1    . G   C 2 2   ? 114.438 66.301  77.325  1.00 32.98 ? 2   G   C N1    1 
ATOM   4824 C  C2    . G   C 2 2   ? 115.228 66.548  76.235  1.00 32.98 ? 2   G   C C2    1 
ATOM   4825 N  N2    . G   C 2 2   ? 114.596 66.546  75.050  1.00 32.98 ? 2   G   C N2    1 
ATOM   4826 N  N3    . G   C 2 2   ? 116.535 66.802  76.294  1.00 32.98 ? 2   G   C N3    1 
ATOM   4827 C  C4    . G   C 2 2   ? 117.022 66.769  77.555  1.00 32.98 ? 2   G   C C4    1 
ATOM   4828 P  P     . C   C 2 3   ? 121.597 71.632  77.232  1.00 21.15 ? 3   C   C P     1 
ATOM   4829 O  OP1   . C   C 2 3   ? 122.767 72.266  76.584  1.00 21.15 ? 3   C   C OP1   1 
ATOM   4830 O  OP2   . C   C 2 3   ? 121.308 71.855  78.664  1.00 21.15 ? 3   C   C OP2   1 
ATOM   4831 O  "O5'" . C   C 2 3   ? 120.287 71.970  76.414  1.00 21.15 ? 3   C   C "O5'" 1 
ATOM   4832 C  "C5'" . C   C 2 3   ? 120.294 72.032  75.004  1.00 21.15 ? 3   C   C "C5'" 1 
ATOM   4833 C  "C4'" . C   C 2 3   ? 118.886 72.173  74.500  1.00 21.15 ? 3   C   C "C4'" 1 
ATOM   4834 O  "O4'" . C   C 2 3   ? 118.086 71.020  74.839  1.00 21.15 ? 3   C   C "O4'" 1 
ATOM   4835 C  "C3'" . C   C 2 3   ? 118.147 73.345  75.102  1.00 21.15 ? 3   C   C "C3'" 1 
ATOM   4836 O  "O3'" . C   C 2 3   ? 118.467 74.541  74.434  1.00 21.15 ? 3   C   C "O3'" 1 
ATOM   4837 C  "C2'" . C   C 2 3   ? 116.686 72.943  74.943  1.00 21.15 ? 3   C   C "C2'" 1 
ATOM   4838 O  "O2'" . C   C 2 3   ? 116.221 73.283  73.651  1.00 21.15 ? 3   C   C "O2'" 1 
ATOM   4839 C  "C1'" . C   C 2 3   ? 116.756 71.414  75.066  1.00 21.15 ? 3   C   C "C1'" 1 
ATOM   4840 N  N1    . C   C 2 3   ? 116.300 70.915  76.381  1.00 21.15 ? 3   C   C N1    1 
ATOM   4841 C  C2    . C   C 2 3   ? 115.035 70.341  76.438  1.00 21.15 ? 3   C   C C2    1 
ATOM   4842 O  O2    . C   C 2 3   ? 114.333 70.324  75.420  1.00 21.15 ? 3   C   C O2    1 
ATOM   4843 N  N3    . C   C 2 3   ? 114.586 69.835  77.598  1.00 21.15 ? 3   C   C N3    1 
ATOM   4844 C  C4    . C   C 2 3   ? 115.371 69.863  78.669  1.00 21.15 ? 3   C   C C4    1 
ATOM   4845 N  N4    . C   C 2 3   ? 114.857 69.358  79.785  1.00 21.15 ? 3   C   C N4    1 
ATOM   4846 C  C5    . C   C 2 3   ? 116.685 70.399  78.634  1.00 21.15 ? 3   C   C C5    1 
ATOM   4847 C  C6    . C   C 2 3   ? 117.091 70.940  77.488  1.00 21.15 ? 3   C   C C6    1 
ATOM   4848 P  P     . C   C 2 4   ? 119.004 75.797  75.261  1.00 16.18 ? 4   C   C P     1 
ATOM   4849 O  OP1   . C   C 2 4   ? 119.304 76.876  74.305  1.00 16.18 ? 4   C   C OP1   1 
ATOM   4850 O  OP2   . C   C 2 4   ? 120.026 75.317  76.217  1.00 16.18 ? 4   C   C OP2   1 
ATOM   4851 O  "O5'" . C   C 2 4   ? 117.773 76.269  76.133  1.00 16.18 ? 4   C   C "O5'" 1 
ATOM   4852 C  "C5'" . C   C 2 4   ? 116.564 76.726  75.552  1.00 16.18 ? 4   C   C "C5'" 1 
ATOM   4853 C  "C4'" . C   C 2 4   ? 115.615 77.160  76.634  1.00 16.18 ? 4   C   C "C4'" 1 
ATOM   4854 O  "O4'" . C   C 2 4   ? 115.343 76.039  77.510  1.00 16.18 ? 4   C   C "O4'" 1 
ATOM   4855 C  "C3'" . C   C 2 4   ? 116.156 78.287  77.516  1.00 16.18 ? 4   C   C "C3'" 1 
ATOM   4856 O  "O3'" . C   C 2 4   ? 115.143 79.253  77.803  1.00 16.18 ? 4   C   C "O3'" 1 
ATOM   4857 C  "C2'" . C   C 2 4   ? 116.594 77.557  78.782  1.00 16.18 ? 4   C   C "C2'" 1 
ATOM   4858 O  "O2'" . C   C 2 4   ? 116.548 78.335  79.951  1.00 16.18 ? 4   C   C "O2'" 1 
ATOM   4859 C  "C1'" . C   C 2 4   ? 115.606 76.402  78.845  1.00 16.18 ? 4   C   C "C1'" 1 
ATOM   4860 N  N1    . C   C 2 4   ? 116.101 75.229  79.567  1.00 16.18 ? 4   C   C N1    1 
ATOM   4861 C  C2    . C   C 2 4   ? 115.190 74.547  80.326  1.00 16.18 ? 4   C   C C2    1 
ATOM   4862 O  O2    . C   C 2 4   ? 114.043 74.962  80.343  1.00 16.18 ? 4   C   C O2    1 
ATOM   4863 N  N3    . C   C 2 4   ? 115.544 73.468  81.025  1.00 16.18 ? 4   C   C N3    1 
ATOM   4864 C  C4    . C   C 2 4   ? 116.790 73.047  80.978  1.00 16.18 ? 4   C   C C4    1 
ATOM   4865 N  N4    . C   C 2 4   ? 117.091 71.961  81.689  1.00 16.18 ? 4   C   C N4    1 
ATOM   4866 C  C5    . C   C 2 4   ? 117.769 73.727  80.202  1.00 16.18 ? 4   C   C C5    1 
ATOM   4867 C  C6    . C   C 2 4   ? 117.375 74.794  79.498  1.00 16.18 ? 4   C   C C6    1 
ATOM   4868 P  P     . A   C 2 5   ? 115.579 80.780  78.032  1.00 7.61  ? 5   A   C P     1 
ATOM   4869 O  OP1   . A   C 2 5   ? 115.044 81.574  76.913  1.00 7.61  ? 5   A   C OP1   1 
ATOM   4870 O  OP2   . A   C 2 5   ? 117.019 80.802  78.307  1.00 7.61  ? 5   A   C OP2   1 
ATOM   4871 O  "O5'" . A   C 2 5   ? 114.807 81.315  79.311  1.00 7.61  ? 5   A   C "O5'" 1 
ATOM   4872 C  "C5'" . A   C 2 5   ? 115.142 80.927  80.637  1.00 7.61  ? 5   A   C "C5'" 1 
ATOM   4873 C  "C4'" . A   C 2 5   ? 114.684 81.957  81.643  1.00 7.61  ? 5   A   C "C4'" 1 
ATOM   4874 O  "O4'" . A   C 2 5   ? 115.558 83.110  81.605  1.00 7.61  ? 5   A   C "O4'" 1 
ATOM   4875 C  "C3'" . A   C 2 5   ? 113.273 82.481  81.439  1.00 7.61  ? 5   A   C "C3'" 1 
ATOM   4876 O  "O3'" . A   C 2 5   ? 112.643 82.806  82.678  1.00 7.61  ? 5   A   C "O3'" 1 
ATOM   4877 C  "C2'" . A   C 2 5   ? 113.496 83.763  80.642  1.00 7.61  ? 5   A   C "C2'" 1 
ATOM   4878 O  "O2'" . A   C 2 5   ? 112.507 84.758  80.809  1.00 7.61  ? 5   A   C "O2'" 1 
ATOM   4879 C  "C1'" . A   C 2 5   ? 114.854 84.242  81.146  1.00 7.61  ? 5   A   C "C1'" 1 
ATOM   4880 N  N9    . A   C 2 5   ? 115.623 84.980  80.144  1.00 7.61  ? 5   A   C N9    1 
ATOM   4881 C  C8    . A   C 2 5   ? 115.541 84.856  78.788  1.00 7.61  ? 5   A   C C8    1 
ATOM   4882 N  N7    . A   C 2 5   ? 116.302 85.694  78.136  1.00 7.61  ? 5   A   C N7    1 
ATOM   4883 C  C5    . A   C 2 5   ? 116.907 86.441  79.131  1.00 7.61  ? 5   A   C C5    1 
ATOM   4884 C  C6    . A   C 2 5   ? 117.830 87.498  79.102  1.00 7.61  ? 5   A   C C6    1 
ATOM   4885 N  N6    . A   C 2 5   ? 118.325 88.011  77.979  1.00 7.61  ? 5   A   C N6    1 
ATOM   4886 N  N1    . A   C 2 5   ? 118.227 88.036  80.271  1.00 7.61  ? 5   A   C N1    1 
ATOM   4887 C  C2    . A   C 2 5   ? 117.730 87.525  81.396  1.00 7.61  ? 5   A   C C2    1 
ATOM   4888 N  N3    . A   C 2 5   ? 116.862 86.530  81.549  1.00 7.61  ? 5   A   C N3    1 
ATOM   4889 C  C4    . A   C 2 5   ? 116.483 86.021  80.369  1.00 7.61  ? 5   A   C C4    1 
ATOM   4890 P  P     . U   C 2 6   ? 111.788 81.700  83.458  1.00 1.56  ? 6   U   C P     1 
ATOM   4891 O  OP1   . U   C 2 6   ? 112.699 80.629  83.896  1.00 1.56  ? 6   U   C OP1   1 
ATOM   4892 O  OP2   . U   C 2 6   ? 110.644 81.313  82.610  1.00 1.56  ? 6   U   C OP2   1 
ATOM   4893 O  "O5'" . U   C 2 6   ? 111.313 82.410  84.801  1.00 1.56  ? 6   U   C "O5'" 1 
ATOM   4894 C  "C5'" . U   C 2 6   ? 110.328 83.438  84.848  1.00 1.56  ? 6   U   C "C5'" 1 
ATOM   4895 C  "C4'" . U   C 2 6   ? 109.479 83.249  86.088  1.00 1.56  ? 6   U   C "C4'" 1 
ATOM   4896 O  "O4'" . U   C 2 6   ? 110.331 83.102  87.252  1.00 1.56  ? 6   U   C "O4'" 1 
ATOM   4897 C  "C3'" . U   C 2 6   ? 108.486 84.332  86.495  1.00 1.56  ? 6   U   C "C3'" 1 
ATOM   4898 O  "O3'" . U   C 2 6   ? 107.252 84.295  85.808  1.00 1.56  ? 6   U   C "O3'" 1 
ATOM   4899 C  "C2'" . U   C 2 6   ? 108.280 83.995  87.957  1.00 1.56  ? 6   U   C "C2'" 1 
ATOM   4900 O  "O2'" . U   C 2 6   ? 107.494 82.821  88.066  1.00 1.56  ? 6   U   C "O2'" 1 
ATOM   4901 C  "C1'" . U   C 2 6   ? 109.699 83.653  88.379  1.00 1.56  ? 6   U   C "C1'" 1 
ATOM   4902 N  N1    . U   C 2 6   ? 110.403 84.870  88.829  1.00 1.56  ? 6   U   C N1    1 
ATOM   4903 C  C2    . U   C 2 6   ? 110.032 85.305  90.079  1.00 1.56  ? 6   U   C C2    1 
ATOM   4904 O  O2    . U   C 2 6   ? 109.294 84.679  90.791  1.00 1.56  ? 6   U   C O2    1 
ATOM   4905 N  N3    . U   C 2 6   ? 110.633 86.435  90.539  1.00 1.56  ? 6   U   C N3    1 
ATOM   4906 C  C4    . U   C 2 6   ? 111.512 87.202  89.832  1.00 1.56  ? 6   U   C C4    1 
ATOM   4907 O  O4    . U   C 2 6   ? 111.968 88.206  90.356  1.00 1.56  ? 6   U   C O4    1 
ATOM   4908 C  C5    . U   C 2 6   ? 111.812 86.727  88.524  1.00 1.56  ? 6   U   C C5    1 
ATOM   4909 C  C6    . U   C 2 6   ? 111.251 85.616  88.062  1.00 1.56  ? 6   U   C C6    1 
ATOM   4910 P  P     . G   C 2 7   ? 106.834 85.491  84.839  1.00 1.56  ? 7   G   C P     1 
ATOM   4911 O  OP1   . G   C 2 7   ? 105.614 85.048  84.152  1.00 1.56  ? 7   G   C OP1   1 
ATOM   4912 O  OP2   . G   C 2 7   ? 108.028 85.838  84.048  1.00 1.56  ? 7   G   C OP2   1 
ATOM   4913 O  "O5'" . G   C 2 7   ? 106.541 86.763  85.754  1.00 1.56  ? 7   G   C "O5'" 1 
ATOM   4914 C  "C5'" . G   C 2 7   ? 105.304 87.040  86.401  1.00 1.56  ? 7   G   C "C5'" 1 
ATOM   4915 C  "C4'" . G   C 2 7   ? 105.234 86.651  87.861  1.00 1.56  ? 7   G   C "C4'" 1 
ATOM   4916 O  "O4'" . G   C 2 7   ? 106.538 86.667  88.479  1.00 1.56  ? 7   G   C "O4'" 1 
ATOM   4917 C  "C3'" . G   C 2 7   ? 104.440 87.629  88.709  1.00 1.56  ? 7   G   C "C3'" 1 
ATOM   4918 O  "O3'" . G   C 2 7   ? 103.045 87.484  88.552  1.00 1.56  ? 7   G   C "O3'" 1 
ATOM   4919 C  "C2'" . G   C 2 7   ? 104.933 87.300  90.107  1.00 1.56  ? 7   G   C "C2'" 1 
ATOM   4920 O  "O2'" . G   C 2 7   ? 104.370 86.084  90.581  1.00 1.56  ? 7   G   C "O2'" 1 
ATOM   4921 C  "C1'" . G   C 2 7   ? 106.413 87.073  89.830  1.00 1.56  ? 7   G   C "C1'" 1 
ATOM   4922 N  N9    . G   C 2 7   ? 107.269 88.249  90.069  1.00 1.56  ? 7   G   C N9    1 
ATOM   4923 C  C8    . G   C 2 7   ? 108.037 88.887  89.144  1.00 1.56  ? 7   G   C C8    1 
ATOM   4924 N  N7    . G   C 2 7   ? 108.713 89.879  89.621  1.00 1.56  ? 7   G   C N7    1 
ATOM   4925 C  C5    . G   C 2 7   ? 108.411 89.861  90.962  1.00 1.56  ? 7   G   C C5    1 
ATOM   4926 C  C6    . G   C 2 7   ? 108.873 90.703  91.992  1.00 1.56  ? 7   G   C C6    1 
ATOM   4927 O  O6    . G   C 2 7   ? 109.681 91.626  91.915  1.00 1.56  ? 7   G   C O6    1 
ATOM   4928 N  N1    . G   C 2 7   ? 108.297 90.397  93.198  1.00 1.56  ? 7   G   C N1    1 
ATOM   4929 C  C2    . G   C 2 7   ? 107.428 89.370  93.403  1.00 1.56  ? 7   G   C C2    1 
ATOM   4930 N  N2    . G   C 2 7   ? 107.003 89.206  94.656  1.00 1.56  ? 7   G   C N2    1 
ATOM   4931 N  N3    . G   C 2 7   ? 107.003 88.564  92.450  1.00 1.56  ? 7   G   C N3    1 
ATOM   4932 C  C4    . G   C 2 7   ? 107.544 88.856  91.259  1.00 1.56  ? 7   G   C C4    1 
ATOM   4933 P  P     . C   C 2 8   ? 102.096 88.767  88.479  1.00 1.56  ? 8   C   C P     1 
ATOM   4934 O  OP1   . C   C 2 8   ? 100.770 88.258  88.082  1.00 1.56  ? 8   C   C OP1   1 
ATOM   4935 O  OP2   . C   C 2 8   ? 102.758 89.817  87.697  1.00 1.56  ? 8   C   C OP2   1 
ATOM   4936 O  "O5'" . C   C 2 8   ? 102.017 89.277  89.972  1.00 1.56  ? 8   C   C "O5'" 1 
ATOM   4937 C  "C5'" . C   C 2 8   ? 101.336 88.518  90.947  1.00 1.56  ? 8   C   C "C5'" 1 
ATOM   4938 C  "C4'" . C   C 2 8   ? 101.624 89.015  92.333  1.00 1.56  ? 8   C   C "C4'" 1 
ATOM   4939 O  "O4'" . C   C 2 8   ? 103.048 89.038  92.618  1.00 1.56  ? 8   C   C "O4'" 1 
ATOM   4940 C  "C3'" . C   C 2 8   ? 101.201 90.432  92.594  1.00 1.56  ? 8   C   C "C3'" 1 
ATOM   4941 O  "O3'" . C   C 2 8   ? 99.815  90.530  92.788  1.00 1.56  ? 8   C   C "O3'" 1 
ATOM   4942 C  "C2'" . C   C 2 8   ? 101.985 90.723  93.860  1.00 1.56  ? 8   C   C "C2'" 1 
ATOM   4943 O  "O2'" . C   C 2 8   ? 101.454 89.959  94.929  1.00 1.56  ? 8   C   C "O2'" 1 
ATOM   4944 C  "C1'" . C   C 2 8   ? 103.326 90.105  93.502  1.00 1.56  ? 8   C   C "C1'" 1 
ATOM   4945 N  N1    . C   C 2 8   ? 104.291 91.067  92.904  1.00 1.56  ? 8   C   C N1    1 
ATOM   4946 C  C2    . C   C 2 8   ? 104.981 91.968  93.733  1.00 1.56  ? 8   C   C C2    1 
ATOM   4947 O  O2    . C   C 2 8   ? 104.738 91.994  94.943  1.00 1.56  ? 8   C   C O2    1 
ATOM   4948 N  N3    . C   C 2 8   ? 105.903 92.797  93.205  1.00 1.56  ? 8   C   C N3    1 
ATOM   4949 C  C4    . C   C 2 8   ? 106.148 92.750  91.911  1.00 1.56  ? 8   C   C C4    1 
ATOM   4950 N  N4    . C   C 2 8   ? 107.053 93.586  91.424  1.00 1.56  ? 8   C   C N4    1 
ATOM   4951 C  C5    . C   C 2 8   ? 105.495 91.833  91.050  1.00 1.56  ? 8   C   C C5    1 
ATOM   4952 C  C6    . C   C 2 8   ? 104.572 91.043  91.580  1.00 1.56  ? 8   C   C C6    1 
ATOM   4953 P  P     . A   C 2 9   ? 99.033  91.850  92.364  1.00 1.56  ? 9   A   C P     1 
ATOM   4954 O  OP1   . A   C 2 9   ? 97.630  91.591  92.702  1.00 1.56  ? 9   A   C OP1   1 
ATOM   4955 O  OP2   . A   C 2 9   ? 99.415  92.201  90.988  1.00 1.56  ? 9   A   C OP2   1 
ATOM   4956 O  "O5'" . A   C 2 9   ? 99.608  92.989  93.307  1.00 1.56  ? 9   A   C "O5'" 1 
ATOM   4957 C  "C5'" . A   C 2 9   ? 99.231  93.058  94.661  1.00 1.56  ? 9   A   C "C5'" 1 
ATOM   4958 C  "C4'" . A   C 2 9   ? 100.105 93.993  95.455  1.00 1.56  ? 9   A   C "C4'" 1 
ATOM   4959 O  "O4'" . A   C 2 9   ? 101.502 93.652  95.290  1.00 1.56  ? 9   A   C "O4'" 1 
ATOM   4960 C  "C3'" . A   C 2 9   ? 100.051 95.457  95.086  1.00 1.56  ? 9   A   C "C3'" 1 
ATOM   4961 O  "O3'" . A   C 2 9   ? 98.906  96.098  95.602  1.00 1.56  ? 9   A   C "O3'" 1 
ATOM   4962 C  "C2'" . A   C 2 9   ? 101.337 95.968  95.716  1.00 1.56  ? 9   A   C "C2'" 1 
ATOM   4963 O  "O2'" . A   C 2 9   ? 101.187 96.104  97.116  1.00 1.56  ? 9   A   C "O2'" 1 
ATOM   4964 C  "C1'" . A   C 2 9   ? 102.288 94.804  95.465  1.00 1.56  ? 9   A   C "C1'" 1 
ATOM   4965 N  N9    . A   C 2 9   ? 103.082 95.080  94.262  1.00 1.56  ? 9   A   C N9    1 
ATOM   4966 C  C8    . A   C 2 9   ? 103.005 94.582  93.002  1.00 1.56  ? 9   A   C C8    1 
ATOM   4967 N  N7    . A   C 2 9   ? 103.844 95.137  92.176  1.00 1.56  ? 9   A   C N7    1 
ATOM   4968 C  C5    . A   C 2 9   ? 104.495 96.072  92.950  1.00 1.56  ? 9   A   C C5    1 
ATOM   4969 C  C6    . A   C 2 9   ? 105.502 97.000  92.680  1.00 1.56  ? 9   A   C C6    1 
ATOM   4970 N  N6    . A   C 2 9   ? 106.065 97.132  91.493  1.00 1.56  ? 9   A   C N6    1 
ATOM   4971 N  N1    . A   C 2 9   ? 105.932 97.788  93.679  1.00 1.56  ? 9   A   C N1    1 
ATOM   4972 C  C2    . A   C 2 9   ? 105.379 97.657  94.880  1.00 1.56  ? 9   A   C C2    1 
ATOM   4973 N  N3    . A   C 2 9   ? 104.414 96.837  95.249  1.00 1.56  ? 9   A   C N3    1 
ATOM   4974 C  C4    . A   C 2 9   ? 104.020 96.064  94.227  1.00 1.56  ? 9   A   C C4    1 
ATOM   4975 P  P     . A   C 2 10  ? 98.548  97.607  95.207  1.00 1.56  ? 10  A   C P     1 
ATOM   4976 O  OP1   . A   C 2 10  ? 97.202  97.967  95.642  1.00 1.56  ? 10  A   C OP1   1 
ATOM   4977 O  OP2   . A   C 2 10  ? 98.882  97.804  93.803  1.00 1.56  ? 10  A   C OP2   1 
ATOM   4978 O  "O5'" . A   C 2 10  ? 99.553  98.486  96.040  1.00 1.56  ? 10  A   C "O5'" 1 
ATOM   4979 C  "C5'" . A   C 2 10  ? 99.471  98.594  97.444  1.00 1.56  ? 10  A   C "C5'" 1 
ATOM   4980 C  "C4'" . A   C 2 10  ? 100.589 99.455  97.941  1.00 1.56  ? 10  A   C "C4'" 1 
ATOM   4981 O  "O4'" . A   C 2 10  ? 101.893 99.033  97.459  1.00 1.56  ? 10  A   C "O4'" 1 
ATOM   4982 C  "C3'" . A   C 2 10  ? 100.454 100.865 97.445  1.00 1.56  ? 10  A   C "C3'" 1 
ATOM   4983 O  "O3'" . A   C 2 10  ? 99.478  101.567 98.170  1.00 1.56  ? 10  A   C "O3'" 1 
ATOM   4984 C  "C2'" . A   C 2 10  ? 101.871 101.390 97.568  1.00 1.56  ? 10  A   C "C2'" 1 
ATOM   4985 O  "O2'" . A   C 2 10  ? 102.204 101.624 98.918  1.00 1.56  ? 10  A   C "O2'" 1 
ATOM   4986 C  "C1'" . A   C 2 10  ? 102.653 100.172 97.113  1.00 1.56  ? 10  A   C "C1'" 1 
ATOM   4987 N  N9    . A   C 2 10  ? 103.001 100.143 95.677  1.00 1.56  ? 10  A   C N9    1 
ATOM   4988 C  C8    . A   C 2 10  ? 102.516 99.277  94.739  1.00 1.56  ? 10  A   C C8    1 
ATOM   4989 N  N7    . A   C 2 10  ? 103.044 99.411  93.559  1.00 1.56  ? 10  A   C N7    1 
ATOM   4990 C  C5    . A   C 2 10  ? 103.965 100.413 93.738  1.00 1.56  ? 10  A   C C5    1 
ATOM   4991 C  C6    . A   C 2 10  ? 104.857 101.004 92.850  1.00 1.56  ? 10  A   C C6    1 
ATOM   4992 N  N6    . A   C 2 10  ? 104.941 100.655 91.570  1.00 1.56  ? 10  A   C N6    1 
ATOM   4993 N  N1    . A   C 2 10  ? 105.661 101.976 93.316  1.00 1.56  ? 10  A   C N1    1 
ATOM   4994 C  C2    . A   C 2 10  ? 105.562 102.316 94.602  1.00 1.56  ? 10  A   C C2    1 
ATOM   4995 N  N3    . A   C 2 10  ? 104.756 101.817 95.530  1.00 1.56  ? 10  A   C N3    1 
ATOM   4996 C  C4    . A   C 2 10  ? 103.987 100.837 95.036  1.00 1.56  ? 10  A   C C4    1 
ATOM   4997 P  P     . G   C 2 11  ? 98.721  102.790 97.496  1.00 1.69  ? 11  G   C P     1 
ATOM   4998 O  OP1   . G   C 2 11  ? 97.645  103.203 98.405  1.00 1.69  ? 11  G   C OP1   1 
ATOM   4999 O  OP2   . G   C 2 11  ? 98.432  102.483 96.088  1.00 1.69  ? 11  G   C OP2   1 
ATOM   5000 O  "O5'" . G   C 2 11  ? 99.821  103.915 97.461  1.00 1.69  ? 11  G   C "O5'" 1 
ATOM   5001 C  "C5'" . G   C 2 11  ? 100.354 104.452 98.643  1.00 1.69  ? 11  G   C "C5'" 1 
ATOM   5002 C  "C4'" . G   C 2 11  ? 101.461 105.391 98.306  1.00 1.69  ? 11  G   C "C4'" 1 
ATOM   5003 O  "O4'" . G   C 2 11  ? 102.521 104.704 97.608  1.00 1.69  ? 11  G   C "O4'" 1 
ATOM   5004 C  "C3'" . G   C 2 11  ? 101.062 106.489 97.353  1.00 1.69  ? 11  G   C "C3'" 1 
ATOM   5005 O  "O3'" . G   C 2 11  ? 100.378 107.521 98.017  1.00 1.69  ? 11  G   C "O3'" 1 
ATOM   5006 C  "C2'" . G   C 2 11  ? 102.410 106.923 96.811  1.00 1.69  ? 11  G   C "C2'" 1 
ATOM   5007 O  "O2'" . G   C 2 11  ? 103.117 107.661 97.791  1.00 1.69  ? 11  G   C "O2'" 1 
ATOM   5008 C  "C1'" . G   C 2 11  ? 103.097 105.579 96.664  1.00 1.69  ? 11  G   C "C1'" 1 
ATOM   5009 N  N9    . G   C 2 11  ? 103.035 104.974 95.324  1.00 1.69  ? 11  G   C N9    1 
ATOM   5010 C  C8    . G   C 2 11  ? 102.348 103.847 94.957  1.00 1.69  ? 11  G   C C8    1 
ATOM   5011 N  N7    . G   C 2 11  ? 102.523 103.516 93.715  1.00 1.69  ? 11  G   C N7    1 
ATOM   5012 C  C5    . G   C 2 11  ? 103.452 104.428 93.261  1.00 1.69  ? 11  G   C C5    1 
ATOM   5013 C  C6    . G   C 2 11  ? 104.046 104.566 91.997  1.00 1.69  ? 11  G   C C6    1 
ATOM   5014 O  O6    . G   C 2 11  ? 103.882 103.857 91.014  1.00 1.69  ? 11  G   C O6    1 
ATOM   5015 N  N1    . G   C 2 11  ? 104.900 105.661 91.921  1.00 1.69  ? 11  G   C N1    1 
ATOM   5016 C  C2    . G   C 2 11  ? 105.177 106.490 92.976  1.00 1.69  ? 11  G   C C2    1 
ATOM   5017 N  N2    . G   C 2 11  ? 106.045 107.481 92.728  1.00 1.69  ? 11  G   C N2    1 
ATOM   5018 N  N3    . G   C 2 11  ? 104.624 106.374 94.170  1.00 1.69  ? 11  G   C N3    1 
ATOM   5019 C  C4    . G   C 2 11  ? 103.795 105.323 94.242  1.00 1.69  ? 11  G   C C4    1 
ATOM   5020 P  P     . C   C 2 12  ? 99.180  108.298 97.310  1.00 2.67  ? 12  C   C P     1 
ATOM   5021 O  OP1   . C   C 2 12  ? 98.557  109.184 98.308  1.00 2.67  ? 12  C   C OP1   1 
ATOM   5022 O  OP2   . C   C 2 12  ? 98.351  107.329 96.581  1.00 2.67  ? 12  C   C OP2   1 
ATOM   5023 O  "O5'" . C   C 2 12  ? 99.915  109.181 96.223  1.00 2.67  ? 12  C   C "O5'" 1 
ATOM   5024 C  "C5'" . C   C 2 12  ? 100.780 110.237 96.582  1.00 2.67  ? 12  C   C "C5'" 1 
ATOM   5025 C  "C4'" . C   C 2 12  ? 101.630 110.631 95.403  1.00 2.67  ? 12  C   C "C4'" 1 
ATOM   5026 O  "O4'" . C   C 2 12  ? 102.347 109.490 94.874  1.00 2.67  ? 12  C   C "O4'" 1 
ATOM   5027 C  "C3'" . C   C 2 12  ? 100.845 111.145 94.224  1.00 2.67  ? 12  C   C "C3'" 1 
ATOM   5028 O  "O3'" . C   C 2 12  ? 100.524 112.501 94.383  1.00 2.67  ? 12  C   C "O3'" 1 
ATOM   5029 C  "C2'" . C   C 2 12  ? 101.771 110.888 93.047  1.00 2.67  ? 12  C   C "C2'" 1 
ATOM   5030 O  "O2'" . C   C 2 12  ? 102.733 111.918 92.926  1.00 2.67  ? 12  C   C "O2'" 1 
ATOM   5031 C  "C1'" . C   C 2 12  ? 102.496 109.631 93.479  1.00 2.67  ? 12  C   C "C1'" 1 
ATOM   5032 N  N1    . C   C 2 12  ? 102.042 108.411 92.780  1.00 2.67  ? 12  C   C N1    1 
ATOM   5033 C  C2    . C   C 2 12  ? 102.503 108.197 91.486  1.00 2.67  ? 12  C   C C2    1 
ATOM   5034 O  O2    . C   C 2 12  ? 103.264 109.012 90.966  1.00 2.67  ? 12  C   C O2    1 
ATOM   5035 N  N3    . C   C 2 12  ? 102.115 107.097 90.817  1.00 2.67  ? 12  C   C N3    1 
ATOM   5036 C  C4    . C   C 2 12  ? 101.304 106.235 91.385  1.00 2.67  ? 12  C   C C4    1 
ATOM   5037 N  N4    . C   C 2 12  ? 100.956 105.159 90.682  1.00 2.67  ? 12  C   C N4    1 
ATOM   5038 C  C5    . C   C 2 12  ? 100.806 106.430 92.696  1.00 2.67  ? 12  C   C C5    1 
ATOM   5039 C  C6    . C   C 2 12  ? 101.187 107.523 93.348  1.00 2.67  ? 12  C   C C6    1 
ATOM   5040 P  P     . C   C 2 13  ? 99.342  113.139 93.538  1.00 4.32  ? 13  C   C P     1 
ATOM   5041 O  OP1   . C   C 2 13  ? 99.115  114.509 94.027  1.00 4.32  ? 13  C   C OP1   1 
ATOM   5042 O  OP2   . C   C 2 13  ? 98.229  112.174 93.495  1.00 4.32  ? 13  C   C OP2   1 
ATOM   5043 O  "O5'" . C   C 2 13  ? 99.935  113.228 92.074  1.00 4.32  ? 13  C   C "O5'" 1 
ATOM   5044 C  "C5'" . C   C 2 13  ? 100.871 114.217 91.690  1.00 4.32  ? 13  C   C "C5'" 1 
ATOM   5045 C  "C4'" . C   C 2 13  ? 101.258 114.010 90.254  1.00 4.32  ? 13  C   C "C4'" 1 
ATOM   5046 O  "O4'" . C   C 2 13  ? 101.611 112.640 90.026  1.00 4.32  ? 13  C   C "O4'" 1 
ATOM   5047 C  "C3'" . C   C 2 13  ? 100.126 114.268 89.293  1.00 4.32  ? 13  C   C "C3'" 1 
ATOM   5048 O  "O3'" . C   C 2 13  ? 100.080 115.645 89.009  1.00 4.32  ? 13  C   C "O3'" 1 
ATOM   5049 C  "C2'" . C   C 2 13  ? 100.495 113.418 88.078  1.00 4.32  ? 13  C   C "C2'" 1 
ATOM   5050 O  "O2'" . C   C 2 13  ? 101.333 114.152 87.203  1.00 4.32  ? 13  C   C "O2'" 1 
ATOM   5051 C  "C1'" . C   C 2 13  ? 101.324 112.292 88.697  1.00 4.32  ? 13  C   C "C1'" 1 
ATOM   5052 N  N1    . C   C 2 13  ? 100.739 110.933 88.675  1.00 4.32  ? 13  C   C N1    1 
ATOM   5053 C  C2    . C   C 2 13  ? 100.909 110.120 87.559  1.00 4.32  ? 13  C   C C2    1 
ATOM   5054 O  O2    . C   C 2 13  ? 101.500 110.577 86.580  1.00 4.32  ? 13  C   C O2    1 
ATOM   5055 N  N3    . C   C 2 13  ? 100.454 108.840 87.580  1.00 4.32  ? 13  C   C N3    1 
ATOM   5056 C  C4    . C   C 2 13  ? 99.832  108.378 88.647  1.00 4.32  ? 13  C   C C4    1 
ATOM   5057 N  N4    . C   C 2 13  ? 99.378  107.132 88.636  1.00 4.32  ? 13  C   C N4    1 
ATOM   5058 C  C5    . C   C 2 13  ? 99.662  109.175 89.808  1.00 4.32  ? 13  C   C C5    1 
ATOM   5059 C  C6    . C   C 2 13  ? 100.082 110.436 89.755  1.00 4.32  ? 13  C   C C6    1 
ATOM   5060 P  P     . C   C 2 14  ? 98.737  116.401 88.615  1.00 7.08  ? 14  C   C P     1 
ATOM   5061 O  OP1   . C   C 2 14  ? 99.031  117.841 88.684  1.00 7.08  ? 14  C   C OP1   1 
ATOM   5062 O  OP2   . C   C 2 14  ? 97.651  115.900 89.459  1.00 7.08  ? 14  C   C OP2   1 
ATOM   5063 O  "O5'" . C   C 2 14  ? 98.503  116.031 87.093  1.00 7.08  ? 14  C   C "O5'" 1 
ATOM   5064 C  "C5'" . C   C 2 14  ? 99.365  116.486 86.059  1.00 7.08  ? 14  C   C "C5'" 1 
ATOM   5065 C  "C4'" . C   C 2 14  ? 99.165  115.671 84.805  1.00 7.08  ? 14  C   C "C4'" 1 
ATOM   5066 O  "O4'" . C   C 2 14  ? 99.208  114.251 85.149  1.00 7.08  ? 14  C   C "O4'" 1 
ATOM   5067 C  "C3'" . C   C 2 14  ? 97.800  115.904 84.165  1.00 7.08  ? 14  C   C "C3'" 1 
ATOM   5068 O  "O3'" . C   C 2 14  ? 97.854  115.705 82.755  1.00 7.08  ? 14  C   C "O3'" 1 
ATOM   5069 C  "C2'" . C   C 2 14  ? 96.965  114.790 84.775  1.00 7.08  ? 14  C   C "C2'" 1 
ATOM   5070 O  "O2'" . C   C 2 14  ? 95.812  114.457 84.040  1.00 7.08  ? 14  C   C "O2'" 1 
ATOM   5071 C  "C1'" . C   C 2 14  ? 97.980  113.659 84.789  1.00 7.08  ? 14  C   C "C1'" 1 
ATOM   5072 N  N1    . C   C 2 14  ? 97.648  112.525 85.662  1.00 7.08  ? 14  C   C N1    1 
ATOM   5073 C  C2    . C   C 2 14  ? 97.812  111.265 85.121  1.00 7.08  ? 14  C   C C2    1 
ATOM   5074 O  O2    . C   C 2 14  ? 98.203  111.198 83.963  1.00 7.08  ? 14  C   C O2    1 
ATOM   5075 N  N3    . C   C 2 14  ? 97.500  110.168 85.822  1.00 7.08  ? 14  C   C N3    1 
ATOM   5076 C  C4    . C   C 2 14  ? 97.065  110.303 87.049  1.00 7.08  ? 14  C   C C4    1 
ATOM   5077 N  N4    . C   C 2 14  ? 96.774  109.191 87.714  1.00 7.08  ? 14  C   C N4    1 
ATOM   5078 C  C5    . C   C 2 14  ? 96.899  111.575 87.651  1.00 7.08  ? 14  C   C C5    1 
ATOM   5079 C  C6    . C   C 2 14  ? 97.205  112.656 86.934  1.00 7.08  ? 14  C   C C6    1 
ATOM   5080 P  P     . U   C 2 15  ? 98.149  116.921 81.749  1.00 10.70 ? 15  U   C P     1 
ATOM   5081 O  OP1   . U   C 2 15  ? 98.284  116.332 80.402  1.00 10.70 ? 15  U   C OP1   1 
ATOM   5082 O  OP2   . U   C 2 15  ? 99.196  117.816 82.276  1.00 10.70 ? 15  U   C OP2   1 
ATOM   5083 O  "O5'" . U   C 2 15  ? 96.839  117.812 81.802  1.00 10.70 ? 15  U   C "O5'" 1 
ATOM   5084 C  "C5'" . U   C 2 15  ? 95.600  117.379 81.270  1.00 10.70 ? 15  U   C "C5'" 1 
ATOM   5085 C  "C4'" . U   C 2 15  ? 94.545  118.445 81.433  1.00 10.70 ? 15  U   C "C4'" 1 
ATOM   5086 O  "O4'" . U   C 2 15  ? 94.355  118.715 82.850  1.00 10.70 ? 15  U   C "O4'" 1 
ATOM   5087 C  "C3'" . U   C 2 15  ? 94.882  119.790 80.793  1.00 10.70 ? 15  U   C "C3'" 1 
ATOM   5088 O  "O3'" . U   C 2 15  ? 93.725  120.356 80.175  1.00 10.70 ? 15  U   C "O3'" 1 
ATOM   5089 C  "C2'" . U   C 2 15  ? 95.371  120.621 81.967  1.00 10.70 ? 15  U   C "C2'" 1 
ATOM   5090 O  "O2'" . U   C 2 15  ? 95.241  122.014 81.803  1.00 10.70 ? 15  U   C "O2'" 1 
ATOM   5091 C  "C1'" . U   C 2 15  ? 94.499  120.100 83.090  1.00 10.70 ? 15  U   C "C1'" 1 
ATOM   5092 N  N1    . U   C 2 15  ? 95.085  120.306 84.423  1.00 10.70 ? 15  U   C N1    1 
ATOM   5093 C  C2    . U   C 2 15  ? 94.848  121.523 85.014  1.00 10.70 ? 15  U   C C2    1 
ATOM   5094 O  O2    . U   C 2 15  ? 94.190  122.397 84.499  1.00 10.70 ? 15  U   C O2    1 
ATOM   5095 N  N3    . U   C 2 15  ? 95.413  121.700 86.239  1.00 10.70 ? 15  U   C N3    1 
ATOM   5096 C  C4    . U   C 2 15  ? 96.180  120.814 86.936  1.00 10.70 ? 15  U   C C4    1 
ATOM   5097 O  O4    . U   C 2 15  ? 96.597  121.143 88.044  1.00 10.70 ? 15  U   C O4    1 
ATOM   5098 C  C5    . U   C 2 15  ? 96.395  119.574 86.264  1.00 10.70 ? 15  U   C C5    1 
ATOM   5099 C  C6    . U   C 2 15  ? 95.858  119.373 85.058  1.00 10.70 ? 15  U   C C6    1 
ATOM   5100 P  P     . G   C 2 16  ? 93.548  120.149 78.594  1.00 23.00 ? 16  G   C P     1 
ATOM   5101 O  OP1   . G   C 2 16  ? 94.057  118.798 78.278  1.00 23.00 ? 16  G   C OP1   1 
ATOM   5102 O  OP2   . G   C 2 16  ? 94.138  121.324 77.913  1.00 23.00 ? 16  G   C OP2   1 
ATOM   5103 O  "O5'" . G   C 2 16  ? 91.988  120.132 78.283  1.00 23.00 ? 16  G   C "O5'" 1 
ATOM   5104 C  "C5'" . G   C 2 16  ? 91.203  121.312 78.286  1.00 23.00 ? 16  G   C "C5'" 1 
ATOM   5105 C  "C4'" . G   C 2 16  ? 90.410  121.421 77.006  1.00 23.00 ? 16  G   C "C4'" 1 
ATOM   5106 O  "O4'" . G   C 2 16  ? 89.603  120.241 76.794  1.00 23.00 ? 16  G   C "O4'" 1 
ATOM   5107 C  "C3'" . G   C 2 16  ? 89.400  122.535 76.928  1.00 23.00 ? 16  G   C "C3'" 1 
ATOM   5108 O  "O3'" . G   C 2 16  ? 89.971  123.799 76.682  1.00 23.00 ? 16  G   C "O3'" 1 
ATOM   5109 C  "C2'" . G   C 2 16  ? 88.543  122.081 75.745  1.00 23.00 ? 16  G   C "C2'" 1 
ATOM   5110 O  "O2'" . G   C 2 16  ? 89.196  122.366 74.520  1.00 23.00 ? 16  G   C "O2'" 1 
ATOM   5111 C  "C1'" . G   C 2 16  ? 88.531  120.564 75.926  1.00 23.00 ? 16  G   C "C1'" 1 
ATOM   5112 N  N9    . G   C 2 16  ? 87.240  120.129 76.490  1.00 23.00 ? 16  G   C N9    1 
ATOM   5113 C  C8    . G   C 2 16  ? 86.880  120.143 77.806  1.00 23.00 ? 16  G   C C8    1 
ATOM   5114 N  N7    . G   C 2 16  ? 85.653  119.767 78.000  1.00 23.00 ? 16  G   C N7    1 
ATOM   5115 C  C5    . G   C 2 16  ? 85.144  119.545 76.739  1.00 23.00 ? 16  G   C C5    1 
ATOM   5116 C  C6    . G   C 2 16  ? 83.861  119.116 76.337  1.00 23.00 ? 16  G   C C6    1 
ATOM   5117 O  O6    . G   C 2 16  ? 82.874  118.826 77.004  1.00 23.00 ? 16  G   C O6    1 
ATOM   5118 N  N1    . G   C 2 16  ? 83.756  118.988 74.967  1.00 23.00 ? 16  G   C N1    1 
ATOM   5119 C  C2    . G   C 2 16  ? 84.774  119.243 74.099  1.00 23.00 ? 16  G   C C2    1 
ATOM   5120 N  N2    . G   C 2 16  ? 84.455  119.063 72.809  1.00 23.00 ? 16  G   C N2    1 
ATOM   5121 N  N3    . G   C 2 16  ? 85.982  119.647 74.456  1.00 23.00 ? 16  G   C N3    1 
ATOM   5122 C  C4    . G   C 2 16  ? 86.103  119.780 75.791  1.00 23.00 ? 16  G   C C4    1 
ATOM   5123 P  P     . A   C 2 17  ? 89.328  125.073 77.407  1.00 36.05 ? 17  A   C P     1 
ATOM   5124 O  OP1   . A   C 2 17  ? 89.887  126.264 76.726  1.00 36.05 ? 17  A   C OP1   1 
ATOM   5125 O  OP2   . A   C 2 17  ? 89.495  124.960 78.875  1.00 36.05 ? 17  A   C OP2   1 
ATOM   5126 O  "O5'" . A   C 2 17  ? 87.787  124.938 77.040  1.00 36.05 ? 17  A   C "O5'" 1 
ATOM   5127 C  "C5'" . A   C 2 17  ? 87.162  125.714 76.033  1.00 36.05 ? 17  A   C "C5'" 1 
ATOM   5128 C  "C4'" . A   C 2 17  ? 86.356  126.832 76.647  1.00 36.05 ? 17  A   C "C4'" 1 
ATOM   5129 O  "O4'" . A   C 2 17  ? 85.756  127.607 75.572  1.00 36.05 ? 17  A   C "O4'" 1 
ATOM   5130 C  "C3'" . A   C 2 17  ? 85.184  126.354 77.509  1.00 36.05 ? 17  A   C "C3'" 1 
ATOM   5131 O  "O3'" . A   C 2 17  ? 84.872  127.354 78.482  1.00 36.05 ? 17  A   C "O3'" 1 
ATOM   5132 C  "C2'" . A   C 2 17  ? 84.068  126.292 76.480  1.00 36.05 ? 17  A   C "C2'" 1 
ATOM   5133 O  "O2'" . A   C 2 17  ? 82.765  126.276 77.014  1.00 36.05 ? 17  A   C "O2'" 1 
ATOM   5134 C  "C1'" . A   C 2 17  ? 84.352  127.577 75.720  1.00 36.05 ? 17  A   C "C1'" 1 
ATOM   5135 N  N9    . A   C 2 17  ? 83.728  127.673 74.403  1.00 36.05 ? 17  A   C N9    1 
ATOM   5136 C  C8    . A   C 2 17  ? 84.015  126.993 73.254  1.00 36.05 ? 17  A   C C8    1 
ATOM   5137 N  N7    . A   C 2 17  ? 83.270  127.331 72.239  1.00 36.05 ? 17  A   C N7    1 
ATOM   5138 C  C5    . A   C 2 17  ? 82.457  128.332 72.753  1.00 36.05 ? 17  A   C C5    1 
ATOM   5139 C  C6    . A   C 2 17  ? 81.426  129.110 72.192  1.00 36.05 ? 17  A   C C6    1 
ATOM   5140 N  N6    . A   C 2 17  ? 81.031  129.019 70.923  1.00 36.05 ? 17  A   C N6    1 
ATOM   5141 N  N1    . A   C 2 17  ? 80.802  130.005 72.991  1.00 36.05 ? 17  A   C N1    1 
ATOM   5142 C  C2    . A   C 2 17  ? 81.183  130.104 74.270  1.00 36.05 ? 17  A   C C2    1 
ATOM   5143 N  N3    . A   C 2 17  ? 82.130  129.424 74.910  1.00 36.05 ? 17  A   C N3    1 
ATOM   5144 C  C4    . A   C 2 17  ? 82.730  128.544 74.087  1.00 36.05 ? 17  A   C C4    1 
ATOM   5145 P  P     . A   C 2 18  ? 84.423  126.975 79.980  1.00 37.56 ? 18  A   C P     1 
ATOM   5146 O  OP1   . A   C 2 18  ? 84.503  128.245 80.733  1.00 37.56 ? 18  A   C OP1   1 
ATOM   5147 O  OP2   . A   C 2 18  ? 85.147  125.787 80.473  1.00 37.56 ? 18  A   C OP2   1 
ATOM   5148 O  "O5'" . A   C 2 18  ? 82.882  126.603 79.824  1.00 37.56 ? 18  A   C "O5'" 1 
ATOM   5149 C  "C5'" . A   C 2 18  ? 82.395  125.267 79.961  1.00 37.56 ? 18  A   C "C5'" 1 
ATOM   5150 C  "C4'" . A   C 2 18  ? 80.892  125.247 80.141  1.00 37.56 ? 18  A   C "C4'" 1 
ATOM   5151 O  "O4'" . A   C 2 18  ? 80.475  125.751 81.447  1.00 37.56 ? 18  A   C "O4'" 1 
ATOM   5152 C  "C3'" . A   C 2 18  ? 80.157  126.114 79.111  1.00 37.56 ? 18  A   C "C3'" 1 
ATOM   5153 O  "O3'" . A   C 2 18  ? 78.910  125.584 78.662  1.00 37.56 ? 18  A   C "O3'" 1 
ATOM   5154 C  "C2'" . A   C 2 18  ? 79.862  127.367 79.926  1.00 37.56 ? 18  A   C "C2'" 1 
ATOM   5155 O  "O2'" . A   C 2 18  ? 78.823  128.167 79.409  1.00 37.56 ? 18  A   C "O2'" 1 
ATOM   5156 C  "C1'" . A   C 2 18  ? 79.464  126.712 81.230  1.00 37.56 ? 18  A   C "C1'" 1 
ATOM   5157 N  N9    . A   C 2 18  ? 79.327  127.613 82.371  1.00 37.56 ? 18  A   C N9    1 
ATOM   5158 C  C8    . A   C 2 18  ? 78.152  127.805 83.051  1.00 37.56 ? 18  A   C C8    1 
ATOM   5159 N  N7    . A   C 2 18  ? 78.238  128.622 84.064  1.00 37.56 ? 18  A   C N7    1 
ATOM   5160 C  C5    . A   C 2 18  ? 79.572  128.979 84.056  1.00 37.56 ? 18  A   C C5    1 
ATOM   5161 C  C6    . A   C 2 18  ? 80.302  129.831 84.891  1.00 37.56 ? 18  A   C C6    1 
ATOM   5162 N  N6    . A   C 2 18  ? 79.769  130.482 85.919  1.00 37.56 ? 18  A   C N6    1 
ATOM   5163 N  N1    . A   C 2 18  ? 81.613  129.975 84.631  1.00 37.56 ? 18  A   C N1    1 
ATOM   5164 C  C2    . A   C 2 18  ? 82.129  129.314 83.591  1.00 37.56 ? 18  A   C C2    1 
ATOM   5165 N  N3    . A   C 2 18  ? 81.549  128.485 82.730  1.00 37.56 ? 18  A   C N3    1 
ATOM   5166 C  C4    . A   C 2 18  ? 80.260  128.349 83.034  1.00 37.56 ? 18  A   C C4    1 
ATOM   5167 P  P     . A   C 2 19  ? 78.282  124.155 79.023  1.00 38.06 ? 19  A   C P     1 
ATOM   5168 O  OP1   . A   C 2 19  ? 78.179  123.932 80.479  1.00 38.06 ? 19  A   C OP1   1 
ATOM   5169 O  OP2   . A   C 2 19  ? 78.840  123.118 78.124  1.00 38.06 ? 19  A   C OP2   1 
ATOM   5170 O  "O5'" . A   C 2 19  ? 76.801  124.400 78.519  1.00 38.06 ? 19  A   C "O5'" 1 
ATOM   5171 C  "C5'" . A   C 2 19  ? 76.359  123.732 77.362  1.00 38.06 ? 19  A   C "C5'" 1 
ATOM   5172 C  "C4'" . A   C 2 19  ? 75.003  124.181 76.909  1.00 38.06 ? 19  A   C "C4'" 1 
ATOM   5173 O  "O4'" . A   C 2 19  ? 75.039  125.579 76.544  1.00 38.06 ? 19  A   C "O4'" 1 
ATOM   5174 C  "C3'" . A   C 2 19  ? 74.504  123.435 75.673  1.00 38.06 ? 19  A   C "C3'" 1 
ATOM   5175 O  "O3'" . A   C 2 19  ? 73.244  122.835 75.895  1.00 38.06 ? 19  A   C "O3'" 1 
ATOM   5176 C  "C2'" . A   C 2 19  ? 74.497  124.472 74.536  1.00 38.06 ? 19  A   C "C2'" 1 
ATOM   5177 O  "O2'" . A   C 2 19  ? 73.165  124.814 74.175  1.00 38.06 ? 19  A   C "O2'" 1 
ATOM   5178 C  "C1'" . A   C 2 19  ? 75.172  125.696 75.164  1.00 38.06 ? 19  A   C "C1'" 1 
ATOM   5179 N  N9    . A   C 2 19  ? 76.599  125.854 74.830  1.00 38.06 ? 19  A   C N9    1 
ATOM   5180 C  C8    . A   C 2 19  ? 77.625  126.078 75.706  1.00 38.06 ? 19  A   C C8    1 
ATOM   5181 N  N7    . A   C 2 19  ? 78.798  126.186 75.148  1.00 38.06 ? 19  A   C N7    1 
ATOM   5182 C  C5    . A   C 2 19  ? 78.521  126.060 73.804  1.00 38.06 ? 19  A   C C5    1 
ATOM   5183 C  C6    . A   C 2 19  ? 79.342  126.085 72.677  1.00 38.06 ? 19  A   C C6    1 
ATOM   5184 N  N6    . A   C 2 19  ? 80.648  126.250 72.753  1.00 38.06 ? 19  A   C N6    1 
ATOM   5185 N  N1    . A   C 2 19  ? 78.784  125.934 71.461  1.00 38.06 ? 19  A   C N1    1 
ATOM   5186 C  C2    . A   C 2 19  ? 77.464  125.753 71.402  1.00 38.06 ? 19  A   C C2    1 
ATOM   5187 N  N3    . A   C 2 19  ? 76.581  125.700 72.392  1.00 38.06 ? 19  A   C N3    1 
ATOM   5188 C  C4    . A   C 2 19  ? 77.176  125.860 73.587  1.00 38.06 ? 19  A   C C4    1 
ATOM   5189 P  P     . C   C 2 20  ? 73.180  121.303 76.356  1.00 33.67 ? 20  C   C P     1 
ATOM   5190 O  OP1   . C   C 2 20  ? 71.769  120.948 76.638  1.00 33.67 ? 20  C   C OP1   1 
ATOM   5191 O  OP2   . C   C 2 20  ? 74.198  121.104 77.407  1.00 33.67 ? 20  C   C OP2   1 
ATOM   5192 O  "O5'" . C   C 2 20  ? 73.643  120.554 75.040  1.00 33.67 ? 20  C   C "O5'" 1 
ATOM   5193 C  "C5'" . C   C 2 20  ? 72.909  120.680 73.834  1.00 33.67 ? 20  C   C "C5'" 1 
ATOM   5194 C  "C4'" . C   C 2 20  ? 73.825  120.647 72.639  1.00 33.67 ? 20  C   C "C4'" 1 
ATOM   5195 O  "O4'" . C   C 2 20  ? 74.819  121.694 72.712  1.00 33.67 ? 20  C   C "O4'" 1 
ATOM   5196 C  "C3'" . C   C 2 20  ? 74.637  119.370 72.530  1.00 33.67 ? 20  C   C "C3'" 1 
ATOM   5197 O  "O3'" . C   C 2 20  ? 73.888  118.352 71.913  1.00 33.67 ? 20  C   C "O3'" 1 
ATOM   5198 C  "C2'" . C   C 2 20  ? 75.822  119.792 71.677  1.00 33.67 ? 20  C   C "C2'" 1 
ATOM   5199 O  "O2'" . C   C 2 20  ? 75.478  119.752 70.304  1.00 33.67 ? 20  C   C "O2'" 1 
ATOM   5200 C  "C1'" . C   C 2 20  ? 75.997  121.253 72.074  1.00 33.67 ? 20  C   C "C1'" 1 
ATOM   5201 N  N1    . C   C 2 20  ? 77.157  121.591 72.921  1.00 33.67 ? 20  C   C N1    1 
ATOM   5202 C  C2    . C   C 2 20  ? 78.288  122.215 72.387  1.00 33.67 ? 20  C   C C2    1 
ATOM   5203 O  O2    . C   C 2 20  ? 78.410  122.270 71.156  1.00 33.67 ? 20  C   C O2    1 
ATOM   5204 N  N3    . C   C 2 20  ? 79.278  122.632 73.207  1.00 33.67 ? 20  C   C N3    1 
ATOM   5205 C  C4    . C   C 2 20  ? 79.123  122.544 74.524  1.00 33.67 ? 20  C   C C4    1 
ATOM   5206 N  N4    . C   C 2 20  ? 80.105  122.982 75.306  1.00 33.67 ? 20  C   C N4    1 
ATOM   5207 C  C5    . C   C 2 20  ? 77.927  122.047 75.101  1.00 33.67 ? 20  C   C C5    1 
ATOM   5208 C  C6    . C   C 2 20  ? 77.057  121.490 74.275  1.00 33.67 ? 20  C   C C6    1 
ATOM   5209 P  P     . C   C 2 21  ? 74.087  116.824 72.328  1.00 27.41 ? 21  C   C P     1 
ATOM   5210 O  OP1   . C   C 2 21  ? 73.176  116.030 71.469  1.00 27.41 ? 21  C   C OP1   1 
ATOM   5211 O  OP2   . C   C 2 21  ? 74.016  116.710 73.801  1.00 27.41 ? 21  C   C OP2   1 
ATOM   5212 O  "O5'" . C   C 2 21  ? 75.587  116.552 71.880  1.00 27.41 ? 21  C   C "O5'" 1 
ATOM   5213 C  "C5'" . C   C 2 21  ? 75.891  116.421 70.504  1.00 27.41 ? 21  C   C "C5'" 1 
ATOM   5214 C  "C4'" . C   C 2 21  ? 77.372  116.436 70.240  1.00 27.41 ? 21  C   C "C4'" 1 
ATOM   5215 O  "O4'" . C   C 2 21  ? 77.961  117.672 70.704  1.00 27.41 ? 21  C   C "O4'" 1 
ATOM   5216 C  "C3'" . C   C 2 21  ? 78.151  115.356 70.952  1.00 27.41 ? 21  C   C "C3'" 1 
ATOM   5217 O  "O3'" . C   C 2 21  ? 78.146  114.162 70.206  1.00 27.41 ? 21  C   C "O3'" 1 
ATOM   5218 C  "C2'" . C   C 2 21  ? 79.557  115.946 71.019  1.00 27.41 ? 21  C   C "C2'" 1 
ATOM   5219 O  "O2'" . C   C 2 21  ? 80.245  115.696 69.808  1.00 27.41 ? 21  C   C "O2'" 1 
ATOM   5220 C  "C1'" . C   C 2 21  ? 79.290  117.448 71.095  1.00 27.41 ? 21  C   C "C1'" 1 
ATOM   5221 N  N1    . C   C 2 21  ? 79.527  118.029 72.433  1.00 27.41 ? 21  C   C N1    1 
ATOM   5222 C  C2    . C   C 2 21  ? 80.730  118.698 72.700  1.00 27.41 ? 21  C   C C2    1 
ATOM   5223 O  O2    . C   C 2 21  ? 81.634  118.770 71.862  1.00 27.41 ? 21  C   C O2    1 
ATOM   5224 N  N3    . C   C 2 21  ? 80.938  119.251 73.913  1.00 27.41 ? 21  C   C N3    1 
ATOM   5225 C  C4    . C   C 2 21  ? 79.977  119.191 74.828  1.00 27.41 ? 21  C   C C4    1 
ATOM   5226 N  N4    . C   C 2 21  ? 80.254  119.745 75.998  1.00 27.41 ? 21  C   C N4    1 
ATOM   5227 C  C5    . C   C 2 21  ? 78.737  118.545 74.588  1.00 27.41 ? 21  C   C C5    1 
ATOM   5228 C  C6    . C   C 2 21  ? 78.571  117.959 73.398  1.00 27.41 ? 21  C   C C6    1 
ATOM   5229 P  P     . C   C 2 22  ? 77.338  112.877 70.711  1.00 18.28 ? 22  C   C P     1 
ATOM   5230 O  OP1   . C   C 2 22  ? 77.447  111.848 69.653  1.00 18.28 ? 22  C   C OP1   1 
ATOM   5231 O  OP2   . C   C 2 22  ? 76.011  113.310 71.203  1.00 18.28 ? 22  C   C OP2   1 
ATOM   5232 O  "O5'" . C   C 2 22  ? 78.177  112.381 71.953  1.00 18.28 ? 22  C   C "O5'" 1 
ATOM   5233 C  "C5'" . C   C 2 22  ? 79.519  111.954 71.820  1.00 18.28 ? 22  C   C "C5'" 1 
ATOM   5234 C  "C4'" . C   C 2 22  ? 80.095  111.701 73.179  1.00 18.28 ? 22  C   C "C4'" 1 
ATOM   5235 O  "O4'" . C   C 2 22  ? 80.091  112.943 73.932  1.00 18.28 ? 22  C   C "O4'" 1 
ATOM   5236 C  "C3'" . C   C 2 22  ? 79.271  110.705 73.988  1.00 18.28 ? 22  C   C "C3'" 1 
ATOM   5237 O  "O3'" . C   C 2 22  ? 80.127  109.759 74.597  1.00 18.28 ? 22  C   C "O3'" 1 
ATOM   5238 C  "C2'" . C   C 2 22  ? 78.606  111.564 75.057  1.00 18.28 ? 22  C   C "C2'" 1 
ATOM   5239 O  "O2'" . C   C 2 22  ? 78.373  110.909 76.275  1.00 18.28 ? 22  C   C "O2'" 1 
ATOM   5240 C  "C1'" . C   C 2 22  ? 79.600  112.692 75.222  1.00 18.28 ? 22  C   C "C1'" 1 
ATOM   5241 N  N1    . C   C 2 22  ? 79.000  113.911 75.769  1.00 18.28 ? 22  C   C N1    1 
ATOM   5242 C  C2    . C   C 2 22  ? 79.629  114.526 76.831  1.00 18.28 ? 22  C   C C2    1 
ATOM   5243 O  O2    . C   C 2 22  ? 80.679  114.043 77.241  1.00 18.28 ? 22  C   C O2    1 
ATOM   5244 N  N3    . C   C 2 22  ? 79.098  115.624 77.386  1.00 18.28 ? 22  C   C N3    1 
ATOM   5245 C  C4    . C   C 2 22  ? 77.970  116.112 76.915  1.00 18.28 ? 22  C   C C4    1 
ATOM   5246 N  N4    . C   C 2 22  ? 77.486  117.205 77.497  1.00 18.28 ? 22  C   C N4    1 
ATOM   5247 C  C5    . C   C 2 22  ? 77.286  115.494 75.847  1.00 18.28 ? 22  C   C C5    1 
ATOM   5248 C  C6    . C   C 2 22  ? 77.846  114.427 75.285  1.00 18.28 ? 22  C   C C6    1 
ATOM   5249 P  P     . A   C 2 23  ? 79.899  108.203 74.314  1.00 7.99  ? 23  A   C P     1 
ATOM   5250 O  OP1   . A   C 2 23  ? 80.960  107.720 73.413  1.00 7.99  ? 23  A   C OP1   1 
ATOM   5251 O  OP2   . A   C 2 23  ? 78.490  107.946 73.983  1.00 7.99  ? 23  A   C OP2   1 
ATOM   5252 O  "O5'" . A   C 2 23  ? 80.186  107.543 75.711  1.00 7.99  ? 23  A   C "O5'" 1 
ATOM   5253 C  "C5'" . A   C 2 23  ? 79.572  108.039 76.888  1.00 7.99  ? 23  A   C "C5'" 1 
ATOM   5254 C  "C4'" . A   C 2 23  ? 79.744  107.054 78.007  1.00 7.99  ? 23  A   C "C4'" 1 
ATOM   5255 O  "O4'" . A   C 2 23  ? 78.883  105.915 77.784  1.00 7.99  ? 23  A   C "O4'" 1 
ATOM   5256 C  "C3'" . A   C 2 23  ? 81.159  106.516 78.142  1.00 7.99  ? 23  A   C "C3'" 1 
ATOM   5257 O  "O3'" . A   C 2 23  ? 81.470  106.257 79.498  1.00 7.99  ? 23  A   C "O3'" 1 
ATOM   5258 C  "C2'" . A   C 2 23  ? 81.112  105.186 77.407  1.00 7.99  ? 23  A   C "C2'" 1 
ATOM   5259 O  "O2'" . A   C 2 23  ? 81.973  104.195 77.918  1.00 7.99  ? 23  A   C "O2'" 1 
ATOM   5260 C  "C1'" . A   C 2 23  ? 79.652  104.759 77.537  1.00 7.99  ? 23  A   C "C1'" 1 
ATOM   5261 N  N9    . A   C 2 23  ? 79.167  104.041 76.364  1.00 7.99  ? 23  A   C N9    1 
ATOM   5262 C  C8    . A   C 2 23  ? 79.579  104.197 75.068  1.00 7.99  ? 23  A   C C8    1 
ATOM   5263 N  N7    . A   C 2 23  ? 79.006  103.357 74.248  1.00 7.99  ? 23  A   C N7    1 
ATOM   5264 C  C5    . A   C 2 23  ? 78.188  102.590 75.062  1.00 7.99  ? 23  A   C C5    1 
ATOM   5265 C  C6    . A   C 2 23  ? 77.319  101.520 74.812  1.00 7.99  ? 23  A   C C6    1 
ATOM   5266 N  N6    . A   C 2 23  ? 77.100  101.010 73.608  1.00 7.99  ? 23  A   C N6    1 
ATOM   5267 N  N1    . A   C 2 23  ? 76.661  100.974 75.849  1.00 7.99  ? 23  A   C N1    1 
ATOM   5268 C  C2    . A   C 2 23  ? 76.865  101.473 77.063  1.00 7.99  ? 23  A   C C2    1 
ATOM   5269 N  N3    . A   C 2 23  ? 77.661  102.473 77.425  1.00 7.99  ? 23  A   C N3    1 
ATOM   5270 C  C4    . A   C 2 23  ? 78.297  102.995 76.370  1.00 7.99  ? 23  A   C C4    1 
ATOM   5271 P  P     . U   C 2 24  ? 82.147  107.379 80.412  1.00 1.56  ? 24  U   C P     1 
ATOM   5272 O  OP1   . U   C 2 24  ? 81.202  108.495 80.592  1.00 1.56  ? 24  U   C OP1   1 
ATOM   5273 O  OP2   . U   C 2 24  ? 83.514  107.629 79.914  1.00 1.56  ? 24  U   C OP2   1 
ATOM   5274 O  "O5'" . U   C 2 24  ? 82.196  106.674 81.821  1.00 1.56  ? 24  U   C "O5'" 1 
ATOM   5275 C  "C5'" . U   C 2 24  ? 82.965  105.507 82.005  1.00 1.56  ? 24  U   C "C5'" 1 
ATOM   5276 C  "C4'" . U   C 2 24  ? 83.757  105.620 83.274  1.00 1.56  ? 24  U   C "C4'" 1 
ATOM   5277 O  "O4'" . U   C 2 24  ? 82.898  105.811 84.426  1.00 1.56  ? 24  U   C "O4'" 1 
ATOM   5278 C  "C3'" . U   C 2 24  ? 84.608  104.442 83.661  1.00 1.56  ? 24  U   C "C3'" 1 
ATOM   5279 O  "O3'" . U   C 2 24  ? 85.711  104.288 82.781  1.00 1.56  ? 24  U   C "O3'" 1 
ATOM   5280 C  "C2'" . U   C 2 24  ? 84.878  104.776 85.122  1.00 1.56  ? 24  U   C "C2'" 1 
ATOM   5281 O  "O2'" . U   C 2 24  ? 85.692  105.928 85.221  1.00 1.56  ? 24  U   C "O2'" 1 
ATOM   5282 C  "C1'" . U   C 2 24  ? 83.468  105.179 85.549  1.00 1.56  ? 24  U   C "C1'" 1 
ATOM   5283 N  N1    . U   C 2 24  ? 82.643  104.008 85.928  1.00 1.56  ? 24  U   C N1    1 
ATOM   5284 C  C2    . U   C 2 24  ? 82.823  103.466 87.180  1.00 1.56  ? 24  U   C C2    1 
ATOM   5285 O  O2    . U   C 2 24  ? 83.507  103.998 88.016  1.00 1.56  ? 24  U   C O2    1 
ATOM   5286 N  N3    . U   C 2 24  ? 82.059  102.380 87.492  1.00 1.56  ? 24  U   C N3    1 
ATOM   5287 C  C4    . U   C 2 24  ? 81.222  101.707 86.651  1.00 1.56  ? 24  U   C C4    1 
ATOM   5288 O  O4    . U   C 2 24  ? 80.617  100.717 87.032  1.00 1.56  ? 24  U   C O4    1 
ATOM   5289 C  C5    . U   C 2 24  ? 81.140  102.262 85.353  1.00 1.56  ? 24  U   C C5    1 
ATOM   5290 C  C6    . U   C 2 24  ? 81.837  103.349 85.042  1.00 1.56  ? 24  U   C C6    1 
ATOM   5291 P  P     . U   C 2 25  ? 87.061  103.532 83.174  1.00 1.56  ? 25  U   C P     1 
ATOM   5292 O  OP1   . U   C 2 25  ? 87.878  104.418 83.998  1.00 1.56  ? 25  U   C OP1   1 
ATOM   5293 O  OP2   . U   C 2 25  ? 87.651  103.014 81.937  1.00 1.56  ? 25  U   C OP2   1 
ATOM   5294 O  "O5'" . U   C 2 25  ? 86.577  102.305 84.045  1.00 1.56  ? 25  U   C "O5'" 1 
ATOM   5295 C  "C5'" . U   C 2 25  ? 87.477  101.629 84.898  1.00 1.56  ? 25  U   C "C5'" 1 
ATOM   5296 C  "C4'" . U   C 2 25  ? 87.490  102.126 86.317  1.00 1.56  ? 25  U   C "C4'" 1 
ATOM   5297 O  "O4'" . U   C 2 25  ? 86.151  102.286 86.858  1.00 1.56  ? 25  U   C "O4'" 1 
ATOM   5298 C  "C3'" . U   C 2 25  ? 88.193  101.179 87.270  1.00 1.56  ? 25  U   C "C3'" 1 
ATOM   5299 O  "O3'" . U   C 2 25  ? 89.570  101.466 87.297  1.00 1.56  ? 25  U   C "O3'" 1 
ATOM   5300 C  "C2'" . U   C 2 25  ? 87.473  101.415 88.592  1.00 1.56  ? 25  U   C "C2'" 1 
ATOM   5301 O  "O2'" . U   C 2 25  ? 87.928  102.606 89.214  1.00 1.56  ? 25  U   C "O2'" 1 
ATOM   5302 C  "C1'" . U   C 2 25  ? 86.055  101.635 88.103  1.00 1.56  ? 25  U   C "C1'" 1 
ATOM   5303 N  N1    . U   C 2 25  ? 85.169  100.454 88.019  1.00 1.56  ? 25  U   C N1    1 
ATOM   5304 C  C2    . U   C 2 25  ? 84.710  99.841  89.171  1.00 1.56  ? 25  U   C C2    1 
ATOM   5305 O  O2    . U   C 2 25  ? 85.043  100.127 90.299  1.00 1.56  ? 25  U   C O2    1 
ATOM   5306 N  N3    . U   C 2 25  ? 83.850  98.804  88.998  1.00 1.56  ? 25  U   C N3    1 
ATOM   5307 C  C4    . U   C 2 25  ? 83.377  98.343  87.804  1.00 1.56  ? 25  U   C C4    1 
ATOM   5308 O  O4    . U   C 2 25  ? 82.604  97.393  87.798  1.00 1.56  ? 25  U   C O4    1 
ATOM   5309 C  C5    . U   C 2 25  ? 83.850  99.044  86.666  1.00 1.56  ? 25  U   C C5    1 
ATOM   5310 C  C6    . U   C 2 25  ? 84.697  100.052 86.809  1.00 1.56  ? 25  U   C C6    1 
ATOM   5311 P  P     . G   C 2 26  ? 90.657  100.319 87.512  1.00 1.56  ? 26  G   C P     1 
ATOM   5312 O  OP1   . G   C 2 26  ? 91.984  100.962 87.448  1.00 1.56  ? 26  G   C OP1   1 
ATOM   5313 O  OP2   . G   C 2 26  ? 90.316  99.165  86.667  1.00 1.56  ? 26  G   C OP2   1 
ATOM   5314 O  "O5'" . G   C 2 26  ? 90.446  99.862  89.004  1.00 1.56  ? 26  G   C "O5'" 1 
ATOM   5315 C  "C5'" . G   C 2 26  ? 90.893  100.668 90.072  1.00 1.56  ? 26  G   C "C5'" 1 
ATOM   5316 C  "C4'" . G   C 2 26  ? 90.489  100.039 91.359  1.00 1.56  ? 26  G   C "C4'" 1 
ATOM   5317 O  "O4'" . G   C 2 26  ? 89.047  99.991  91.484  1.00 1.56  ? 26  G   C "O4'" 1 
ATOM   5318 C  "C3'" . G   C 2 26  ? 90.908  98.598  91.443  1.00 1.56  ? 26  G   C "C3'" 1 
ATOM   5319 O  "O3'" . G   C 2 26  ? 92.275  98.451  91.767  1.00 1.56  ? 26  G   C "O3'" 1 
ATOM   5320 C  "C2'" . G   C 2 26  ? 89.933  98.041  92.472  1.00 1.56  ? 26  G   C "C2'" 1 
ATOM   5321 O  "O2'" . G   C 2 26  ? 90.299  98.441  93.780  1.00 1.56  ? 26  G   C "O2'" 1 
ATOM   5322 C  "C1'" . G   C 2 26  ? 88.659  98.779  92.092  1.00 1.56  ? 26  G   C "C1'" 1 
ATOM   5323 N  N9    . G   C 2 26  ? 87.787  98.001  91.188  1.00 1.56  ? 26  G   C N9    1 
ATOM   5324 C  C8    . G   C 2 26  ? 87.706  98.018  89.823  1.00 1.56  ? 26  G   C C8    1 
ATOM   5325 N  N7    . G   C 2 26  ? 86.853  97.153  89.355  1.00 1.56  ? 26  G   C N7    1 
ATOM   5326 C  C5    . G   C 2 26  ? 86.306  96.559  90.470  1.00 1.56  ? 26  G   C C5    1 
ATOM   5327 C  C6    . G   C 2 26  ? 85.322  95.566  90.591  1.00 1.56  ? 26  G   C C6    1 
ATOM   5328 O  O6    . G   C 2 26  ? 84.684  95.031  89.693  1.00 1.56  ? 26  G   C O6    1 
ATOM   5329 N  N1    . G   C 2 26  ? 85.100  95.192  91.909  1.00 1.56  ? 26  G   C N1    1 
ATOM   5330 C  C2    . G   C 2 26  ? 85.721  95.768  92.976  1.00 1.56  ? 26  G   C C2    1 
ATOM   5331 N  N2    . G   C 2 26  ? 85.380  95.321  94.184  1.00 1.56  ? 26  G   C N2    1 
ATOM   5332 N  N3    . G   C 2 26  ? 86.643  96.699  92.871  1.00 1.56  ? 26  G   C N3    1 
ATOM   5333 C  C4    . G   C 2 26  ? 86.872  97.061  91.601  1.00 1.56  ? 26  G   C C4    1 
ATOM   5334 P  P     . C   C 2 27  ? 92.946  97.020  91.600  1.00 1.56  ? 27  C   C P     1 
ATOM   5335 O  OP1   . C   C 2 27  ? 94.382  97.132  91.882  1.00 1.56  ? 27  C   C OP1   1 
ATOM   5336 O  OP2   . C   C 2 27  ? 92.471  96.425  90.345  1.00 1.56  ? 27  C   C OP2   1 
ATOM   5337 O  "O5'" . C   C 2 27  ? 92.300  96.276  92.816  1.00 1.56  ? 27  C   C "O5'" 1 
ATOM   5338 C  "C5'" . C   C 2 27  ? 92.267  94.889  92.888  1.00 1.56  ? 27  C   C "C5'" 1 
ATOM   5339 C  "C4'" . C   C 2 27  ? 91.233  94.488  93.887  1.00 1.56  ? 27  C   C "C4'" 1 
ATOM   5340 O  "O4'" . C   C 2 27  ? 89.910  94.990  93.535  1.00 1.56  ? 27  C   C "O4'" 1 
ATOM   5341 C  "C3'" . C   C 2 27  ? 91.043  93.007  94.021  1.00 1.56  ? 27  C   C "C3'" 1 
ATOM   5342 O  "O3'" . C   C 2 27  ? 92.088  92.463  94.786  1.00 1.56  ? 27  C   C "O3'" 1 
ATOM   5343 C  "C2'" . C   C 2 27  ? 89.653  92.933  94.624  1.00 1.56  ? 27  C   C "C2'" 1 
ATOM   5344 O  "O2'" . C   C 2 27  ? 89.657  93.410  95.956  1.00 1.56  ? 27  C   C "O2'" 1 
ATOM   5345 C  "C1'" . C   C 2 27  ? 88.951  93.978  93.769  1.00 1.56  ? 27  C   C "C1'" 1 
ATOM   5346 N  N1    . C   C 2 27  ? 88.394  93.488  92.478  1.00 1.56  ? 27  C   C N1    1 
ATOM   5347 C  C2    . C   C 2 27  ? 87.327  92.576  92.434  1.00 1.56  ? 27  C   C C2    1 
ATOM   5348 O  O2    . C   C 2 27  ? 86.926  92.078  93.480  1.00 1.56  ? 27  C   C O2    1 
ATOM   5349 N  N3    . C   C 2 27  ? 86.772  92.214  91.253  1.00 1.56  ? 27  C   C N3    1 
ATOM   5350 C  C4    . C   C 2 27  ? 87.225  92.750  90.144  1.00 1.56  ? 27  C   C C4    1 
ATOM   5351 N  N4    . C   C 2 27  ? 86.666  92.380  89.002  1.00 1.56  ? 27  C   C N4    1 
ATOM   5352 C  C5    . C   C 2 27  ? 88.242  93.731  90.155  1.00 1.56  ? 27  C   C C5    1 
ATOM   5353 C  C6    . C   C 2 27  ? 88.804  94.048  91.315  1.00 1.56  ? 27  C   C C6    1 
ATOM   5354 P  P     . C   C 2 28  ? 92.557  90.968  94.545  1.00 1.56  ? 28  C   C P     1 
ATOM   5355 O  OP1   . C   C 2 28  ? 93.665  90.664  95.457  1.00 1.56  ? 28  C   C OP1   1 
ATOM   5356 O  OP2   . C   C 2 28  ? 92.682  90.743  93.103  1.00 1.56  ? 28  C   C OP2   1 
ATOM   5357 O  "O5'" . C   C 2 28  ? 91.305  90.177  95.060  1.00 1.56  ? 28  C   C "O5'" 1 
ATOM   5358 C  "C5'" . C   C 2 28  ? 90.905  90.222  96.413  1.00 1.56  ? 28  C   C "C5'" 1 
ATOM   5359 C  "C4'" . C   C 2 28  ? 89.752  89.294  96.561  1.00 1.56  ? 28  C   C "C4'" 1 
ATOM   5360 O  "O4'" . C   C 2 28  ? 88.626  89.682  95.735  1.00 1.56  ? 28  C   C "O4'" 1 
ATOM   5361 C  "C3'" . C   C 2 28  ? 90.102  87.913  96.082  1.00 1.56  ? 28  C   C "C3'" 1 
ATOM   5362 O  "O3'" . C   C 2 28  ? 90.901  87.228  97.015  1.00 1.56  ? 28  C   C "O3'" 1 
ATOM   5363 C  "C2'" . C   C 2 28  ? 88.738  87.326  95.785  1.00 1.56  ? 28  C   C "C2'" 1 
ATOM   5364 O  "O2'" . C   C 2 28  ? 88.060  87.016  96.985  1.00 1.56  ? 28  C   C "O2'" 1 
ATOM   5365 C  "C1'" . C   C 2 28  ? 88.049  88.530  95.161  1.00 1.56  ? 28  C   C "C1'" 1 
ATOM   5366 N  N1    . C   C 2 28  ? 88.062  88.599  93.676  1.00 1.56  ? 28  C   C N1    1 
ATOM   5367 C  C2    . C   C 2 28  ? 87.206  87.761  92.946  1.00 1.56  ? 28  C   C C2    1 
ATOM   5368 O  O2    . C   C 2 28  ? 86.561  86.904  93.539  1.00 1.56  ? 28  C   C O2    1 
ATOM   5369 N  N3    . C   C 2 28  ? 87.124  87.865  91.602  1.00 1.56  ? 28  C   C N3    1 
ATOM   5370 C  C4    . C   C 2 28  ? 87.819  88.784  90.968  1.00 1.56  ? 28  C   C C4    1 
ATOM   5371 N  N4    . C   C 2 28  ? 87.709  88.859  89.636  1.00 1.56  ? 28  C   C N4    1 
ATOM   5372 C  C5    . C   C 2 28  ? 88.636  89.696  91.682  1.00 1.56  ? 28  C   C C5    1 
ATOM   5373 C  C6    . C   C 2 28  ? 88.763  89.542  92.994  1.00 1.56  ? 28  C   C C6    1 
ATOM   5374 P  P     . U   C 2 29  ? 91.885  86.078  96.532  1.00 1.56  ? 29  U   C P     1 
ATOM   5375 O  OP1   . U   C 2 29  ? 92.766  85.662  97.633  1.00 1.56  ? 29  U   C OP1   1 
ATOM   5376 O  OP2   . U   C 2 29  ? 92.487  86.544  95.278  1.00 1.56  ? 29  U   C OP2   1 
ATOM   5377 O  "O5'" . U   C 2 29  ? 90.920  84.881  96.208  1.00 1.56  ? 29  U   C "O5'" 1 
ATOM   5378 C  "C5'" . U   C 2 29  ? 90.085  84.330  97.196  1.00 1.56  ? 29  U   C "C5'" 1 
ATOM   5379 C  "C4'" . U   C 2 29  ? 89.102  83.419  96.541  1.00 1.56  ? 29  U   C "C4'" 1 
ATOM   5380 O  "O4'" . U   C 2 29  ? 88.294  84.116  95.564  1.00 1.56  ? 29  U   C "O4'" 1 
ATOM   5381 C  "C3'" . U   C 2 29  ? 89.748  82.327  95.737  1.00 1.56  ? 29  U   C "C3'" 1 
ATOM   5382 O  "O3'" . U   C 2 29  ? 90.249  81.312  96.569  1.00 1.56  ? 29  U   C "O3'" 1 
ATOM   5383 C  "C2'" . U   C 2 29  ? 88.589  81.881  94.868  1.00 1.56  ? 29  U   C "C2'" 1 
ATOM   5384 O  "O2'" . U   C 2 29  ? 87.651  81.167  95.653  1.00 1.56  ? 29  U   C "O2'" 1 
ATOM   5385 C  "C1'" . U   C 2 29  ? 87.963  83.221  94.524  1.00 1.56  ? 29  U   C "C1'" 1 
ATOM   5386 N  N1    . U   C 2 29  ? 88.300  83.816  93.210  1.00 1.56  ? 29  U   C N1    1 
ATOM   5387 C  C2    . U   C 2 29  ? 87.651  83.369  92.078  1.00 1.56  ? 29  U   C C2    1 
ATOM   5388 O  O2    . U   C 2 29  ? 86.906  82.418  92.079  1.00 1.56  ? 29  U   C O2    1 
ATOM   5389 N  N3    . U   C 2 29  ? 87.947  84.026  90.919  1.00 1.56  ? 29  U   C N3    1 
ATOM   5390 C  C4    . U   C 2 29  ? 88.778  85.111  90.794  1.00 1.56  ? 29  U   C C4    1 
ATOM   5391 O  O4    . U   C 2 29  ? 88.963  85.623  89.694  1.00 1.56  ? 29  U   C O4    1 
ATOM   5392 C  C5    . U   C 2 29  ? 89.373  85.549  92.011  1.00 1.56  ? 29  U   C C5    1 
ATOM   5393 C  C6    . U   C 2 29  ? 89.100  84.921  93.146  1.00 1.56  ? 29  U   C C6    1 
ATOM   5394 P  P     . U   C 2 30  ? 91.578  80.527  96.180  1.00 1.56  ? 30  U   C P     1 
ATOM   5395 O  OP1   . U   C 2 30  ? 91.889  79.529  97.221  1.00 1.56  ? 30  U   C OP1   1 
ATOM   5396 O  OP2   . U   C 2 30  ? 92.575  81.517  95.760  1.00 1.56  ? 30  U   C OP2   1 
ATOM   5397 O  "O5'" . U   C 2 30  ? 91.101  79.690  94.933  1.00 1.56  ? 30  U   C "O5'" 1 
ATOM   5398 C  "C5'" . U   C 2 30  ? 90.226  78.598  95.101  1.00 1.56  ? 30  U   C "C5'" 1 
ATOM   5399 C  "C4'" . U   C 2 30  ? 89.596  78.214  93.794  1.00 1.56  ? 30  U   C "C4'" 1 
ATOM   5400 O  "O4'" . U   C 2 30  ? 88.983  79.367  93.169  1.00 1.56  ? 30  U   C "O4'" 1 
ATOM   5401 C  "C3'" . U   C 2 30  ? 90.541  77.717  92.736  1.00 1.56  ? 30  U   C "C3'" 1 
ATOM   5402 O  "O3'" . U   C 2 30  ? 90.937  76.392  92.996  1.00 1.56  ? 30  U   C "O3'" 1 
ATOM   5403 C  "C2'" . U   C 2 30  ? 89.705  77.896  91.483  1.00 1.56  ? 30  U   C "C2'" 1 
ATOM   5404 O  "O2'" . U   C 2 30  ? 88.644  76.964  91.452  1.00 1.56  ? 30  U   C "O2'" 1 
ATOM   5405 C  "C1'" . U   C 2 30  ? 89.078  79.245  91.769  1.00 1.56  ? 30  U   C "C1'" 1 
ATOM   5406 N  N1    . U   C 2 30  ? 89.801  80.395  91.199  1.00 1.56  ? 30  U   C N1    1 
ATOM   5407 C  C2    . U   C 2 30  ? 89.602  80.611  89.870  1.00 1.56  ? 30  U   C C2    1 
ATOM   5408 O  O2    . U   C 2 30  ? 88.904  79.891  89.192  1.00 1.56  ? 30  U   C O2    1 
ATOM   5409 N  N3    . U   C 2 30  ? 90.238  81.683  89.341  1.00 1.56  ? 30  U   C N3    1 
ATOM   5410 C  C4    . U   C 2 30  ? 91.042  82.563  90.003  1.00 1.56  ? 30  U   C C4    1 
ATOM   5411 O  O4    . U   C 2 30  ? 91.553  83.486  89.381  1.00 1.56  ? 30  U   C O4    1 
ATOM   5412 C  C5    . U   C 2 30  ? 91.204  82.282  91.383  1.00 1.56  ? 30  U   C C5    1 
ATOM   5413 C  C6    . U   C 2 30  ? 90.594  81.229  91.923  1.00 1.56  ? 30  U   C C6    1 
ATOM   5414 P  P     . A   C 2 31  ? 92.306  75.837  92.410  1.00 1.40  ? 31  A   C P     1 
ATOM   5415 O  OP1   . A   C 2 31  ? 92.575  74.491  92.934  1.00 1.40  ? 31  A   C OP1   1 
ATOM   5416 O  OP2   . A   C 2 31  ? 93.277  76.931  92.575  1.00 1.40  ? 31  A   C OP2   1 
ATOM   5417 O  "O5'" . A   C 2 31  ? 92.025  75.701  90.861  1.00 1.40  ? 31  A   C "O5'" 1 
ATOM   5418 C  "C5'" . A   C 2 31  ? 91.146  74.720  90.342  1.00 1.40  ? 31  A   C "C5'" 1 
ATOM   5419 C  "C4'" . A   C 2 31  ? 91.033  74.892  88.857  1.00 1.40  ? 31  A   C "C4'" 1 
ATOM   5420 O  "O4'" . A   C 2 31  ? 90.664  76.247  88.571  1.00 1.40  ? 31  A   C "O4'" 1 
ATOM   5421 C  "C3'" . A   C 2 31  ? 92.319  74.676  88.086  1.00 1.40  ? 31  A   C "C3'" 1 
ATOM   5422 O  "O3'" . A   C 2 31  ? 92.432  73.310  87.766  1.00 1.40  ? 31  A   C "O3'" 1 
ATOM   5423 C  "C2'" . A   C 2 31  ? 92.121  75.528  86.842  1.00 1.40  ? 31  A   C "C2'" 1 
ATOM   5424 O  "O2'" . A   C 2 31  ? 91.395  74.820  85.853  1.00 1.40  ? 31  A   C "O2'" 1 
ATOM   5425 C  "C1'" . A   C 2 31  ? 91.237  76.654  87.361  1.00 1.40  ? 31  A   C "C1'" 1 
ATOM   5426 N  N9    . A   C 2 31  ? 91.883  77.943  87.575  1.00 1.40  ? 31  A   C N9    1 
ATOM   5427 C  C8    . A   C 2 31  ? 92.316  78.488  88.741  1.00 1.40  ? 31  A   C C8    1 
ATOM   5428 N  N7    . A   C 2 31  ? 92.778  79.696  88.609  1.00 1.40  ? 31  A   C N7    1 
ATOM   5429 C  C5    . A   C 2 31  ? 92.615  79.953  87.265  1.00 1.40  ? 31  A   C C5    1 
ATOM   5430 C  C6    . A   C 2 31  ? 92.917  81.057  86.478  1.00 1.40  ? 31  A   C C6    1 
ATOM   5431 N  N6    . A   C 2 31  ? 93.469  82.159  86.947  1.00 1.40  ? 31  A   C N6    1 
ATOM   5432 N  N1    . A   C 2 31  ? 92.639  80.995  85.167  1.00 1.40  ? 31  A   C N1    1 
ATOM   5433 C  C2    . A   C 2 31  ? 92.101  79.873  84.691  1.00 1.40  ? 31  A   C C2    1 
ATOM   5434 N  N3    . A   C 2 31  ? 91.765  78.763  85.328  1.00 1.40  ? 31  A   C N3    1 
ATOM   5435 C  C4    . A   C 2 31  ? 92.072  78.874  86.619  1.00 1.40  ? 31  A   C C4    1 
ATOM   5436 P  P     . G   C 2 32  ? 93.830  72.557  87.654  1.00 3.66  ? 32  G   C P     1 
ATOM   5437 O  OP1   . G   C 2 32  ? 93.545  71.119  87.547  1.00 3.66  ? 32  G   C OP1   1 
ATOM   5438 O  OP2   . G   C 2 32  ? 94.684  72.973  88.764  1.00 3.66  ? 32  G   C OP2   1 
ATOM   5439 O  "O5'" . G   C 2 32  ? 94.385  73.018  86.241  1.00 3.66  ? 32  G   C "O5'" 1 
ATOM   5440 C  "C5'" . G   C 2 32  ? 93.861  72.474  85.038  1.00 3.66  ? 32  G   C "C5'" 1 
ATOM   5441 C  "C4'" . G   C 2 32  ? 94.436  73.143  83.819  1.00 3.66  ? 32  G   C "C4'" 1 
ATOM   5442 O  "O4'" . G   C 2 32  ? 94.267  74.585  83.928  1.00 3.66  ? 32  G   C "O4'" 1 
ATOM   5443 C  "C3'" . G   C 2 32  ? 95.931  72.916  83.623  1.00 3.66  ? 32  G   C "C3'" 1 
ATOM   5444 O  "O3'" . G   C 2 32  ? 96.321  73.090  82.265  1.00 3.66  ? 32  G   C "O3'" 1 
ATOM   5445 C  "C2'" . G   C 2 32  ? 96.524  74.064  84.409  1.00 3.66  ? 32  G   C "C2'" 1 
ATOM   5446 O  "O2'" . G   C 2 32  ? 97.828  74.431  84.022  1.00 3.66  ? 32  G   C "O2'" 1 
ATOM   5447 C  "C1'" . G   C 2 32  ? 95.532  75.182  84.105  1.00 3.66  ? 32  G   C "C1'" 1 
ATOM   5448 N  N9    . G   C 2 32  ? 95.561  76.252  85.091  1.00 3.66  ? 32  G   C N9    1 
ATOM   5449 C  C8    . G   C 2 32  ? 95.702  76.192  86.444  1.00 3.66  ? 32  G   C C8    1 
ATOM   5450 N  N7    . G   C 2 32  ? 95.753  77.363  86.981  1.00 3.66  ? 32  G   C N7    1 
ATOM   5451 C  C5    . G   C 2 32  ? 95.671  78.224  85.910  1.00 3.66  ? 32  G   C C5    1 
ATOM   5452 C  C6    . G   C 2 32  ? 95.704  79.617  85.832  1.00 3.66  ? 32  G   C C6    1 
ATOM   5453 O  O6    . G   C 2 32  ? 95.872  80.432  86.718  1.00 3.66  ? 32  G   C O6    1 
ATOM   5454 N  N1    . G   C 2 32  ? 95.597  80.083  84.527  1.00 3.66  ? 32  G   C N1    1 
ATOM   5455 C  C2    . G   C 2 32  ? 95.516  79.277  83.454  1.00 3.66  ? 32  G   C C2    1 
ATOM   5456 N  N2    . G   C 2 32  ? 95.421  79.881  82.274  1.00 3.66  ? 32  G   C N2    1 
ATOM   5457 N  N3    . G   C 2 32  ? 95.493  77.981  83.505  1.00 3.66  ? 32  G   C N3    1 
ATOM   5458 C  C4    . G   C 2 32  ? 95.606  77.543  84.751  1.00 3.66  ? 32  G   C C4    1 
ATOM   5459 P  P     . U   C 2 33  ? 96.217  71.903  81.204  1.00 12.28 ? 33  U   C P     1 
ATOM   5460 O  OP1   . U   C 2 33  ? 96.511  72.549  79.913  1.00 12.28 ? 33  U   C OP1   1 
ATOM   5461 O  OP2   . U   C 2 33  ? 95.000  71.099  81.396  1.00 12.28 ? 33  U   C OP2   1 
ATOM   5462 O  "O5'" . U   C 2 33  ? 97.450  70.970  81.547  1.00 12.28 ? 33  U   C "O5'" 1 
ATOM   5463 C  "C5'" . U   C 2 33  ? 98.784  71.369  81.278  1.00 12.28 ? 33  U   C "C5'" 1 
ATOM   5464 C  "C4'" . U   C 2 33  ? 99.735  70.242  81.537  1.00 12.28 ? 33  U   C "C4'" 1 
ATOM   5465 O  "O4'" . U   C 2 33  ? 99.648  69.884  82.941  1.00 12.28 ? 33  U   C "O4'" 1 
ATOM   5466 C  "C3'" . U   C 2 33  ? 99.439  68.962  80.752  1.00 12.28 ? 33  U   C "C3'" 1 
ATOM   5467 O  "O3'" . U   C 2 33  ? 100.639 68.298  80.330  1.00 12.28 ? 33  U   C "O3'" 1 
ATOM   5468 C  "C2'" . U   C 2 33  ? 98.659  68.128  81.756  1.00 12.28 ? 33  U   C "C2'" 1 
ATOM   5469 O  "O2'" . U   C 2 33  ? 98.668  66.741  81.520  1.00 12.28 ? 33  U   C "O2'" 1 
ATOM   5470 C  "C1'" . U   C 2 33  ? 99.338  68.513  83.063  1.00 12.28 ? 33  U   C "C1'" 1 
ATOM   5471 N  N1    . U   C 2 33  ? 98.477  68.327  84.235  1.00 12.28 ? 33  U   C N1    1 
ATOM   5472 C  C2    . U   C 2 33  ? 98.639  67.166  84.941  1.00 12.28 ? 33  U   C C2    1 
ATOM   5473 O  O2    . U   C 2 33  ? 99.470  66.344  84.659  1.00 12.28 ? 33  U   C O2    1 
ATOM   5474 N  N3    . U   C 2 33  ? 97.813  67.000  86.007  1.00 12.28 ? 33  U   C N3    1 
ATOM   5475 C  C4    . U   C 2 33  ? 96.843  67.865  86.426  1.00 12.28 ? 33  U   C C4    1 
ATOM   5476 O  O4    . U   C 2 33  ? 96.186  67.562  87.412  1.00 12.28 ? 33  U   C O4    1 
ATOM   5477 C  C5    . U   C 2 33  ? 96.715  69.051  85.643  1.00 12.28 ? 33  U   C C5    1 
ATOM   5478 C  C6    . U   C 2 33  ? 97.514  69.229  84.595  1.00 12.28 ? 33  U   C C6    1 
ATOM   5479 P  P     . G   C 2 34  ? 101.315 68.704  78.927  1.00 24.99 ? 34  G   C P     1 
ATOM   5480 O  OP1   . G   C 2 34  ? 100.921 70.102  78.638  1.00 24.99 ? 34  G   C OP1   1 
ATOM   5481 O  OP2   . G   C 2 34  ? 101.005 67.638  77.953  1.00 24.99 ? 34  G   C OP2   1 
ATOM   5482 O  "O5'" . G   C 2 34  ? 102.887 68.696  79.167  1.00 24.99 ? 34  G   C "O5'" 1 
ATOM   5483 C  "C5'" . G   C 2 34  ? 103.657 67.505  79.083  1.00 24.99 ? 34  G   C "C5'" 1 
ATOM   5484 C  "C4'" . G   C 2 34  ? 104.601 67.516  77.900  1.00 24.99 ? 34  G   C "C4'" 1 
ATOM   5485 O  "O4'" . G   C 2 34  ? 105.532 68.611  77.983  1.00 24.99 ? 34  G   C "O4'" 1 
ATOM   5486 C  "C3'" . G   C 2 34  ? 105.473 66.284  77.740  1.00 24.99 ? 34  G   C "C3'" 1 
ATOM   5487 O  "O3'" . G   C 2 34  ? 104.774 65.242  77.086  1.00 24.99 ? 34  G   C "O3'" 1 
ATOM   5488 C  "C2'" . G   C 2 34  ? 106.661 66.802  76.926  1.00 24.99 ? 34  G   C "C2'" 1 
ATOM   5489 O  "O2'" . G   C 2 34  ? 106.363 66.763  75.543  1.00 24.99 ? 34  G   C "O2'" 1 
ATOM   5490 C  "C1'" . G   C 2 34  ? 106.744 68.269  77.350  1.00 24.99 ? 34  G   C "C1'" 1 
ATOM   5491 N  N9    . G   C 2 34  ? 107.873 68.598  78.248  1.00 24.99 ? 34  G   C N9    1 
ATOM   5492 C  C8    . G   C 2 34  ? 107.842 68.645  79.617  1.00 24.99 ? 34  G   C C8    1 
ATOM   5493 N  N7    . G   C 2 34  ? 108.977 68.970  80.160  1.00 24.99 ? 34  G   C N7    1 
ATOM   5494 C  C5    . G   C 2 34  ? 109.829 69.122  79.089  1.00 24.99 ? 34  G   C C5    1 
ATOM   5495 C  C6    . G   C 2 34  ? 111.194 69.488  79.068  1.00 24.99 ? 34  G   C C6    1 
ATOM   5496 O  O6    . G   C 2 34  ? 111.940 69.803  79.992  1.00 24.99 ? 34  G   C O6    1 
ATOM   5497 N  N1    . G   C 2 34  ? 111.688 69.554  77.781  1.00 24.99 ? 34  G   C N1    1 
ATOM   5498 C  C2    . G   C 2 34  ? 110.963 69.315  76.655  1.00 24.99 ? 34  G   C C2    1 
ATOM   5499 N  N2    . G   C 2 34  ? 111.637 69.425  75.505  1.00 24.99 ? 34  G   C N2    1 
ATOM   5500 N  N3    . G   C 2 34  ? 109.687 68.977  76.659  1.00 24.99 ? 34  G   C N3    1 
ATOM   5501 C  C4    . G   C 2 34  ? 109.169 68.920  77.902  1.00 24.99 ? 34  G   C C4    1 
ATOM   5502 P  P     . C   C 2 35  ? 105.359 63.752  77.065  1.00 31.74 ? 35  C   C P     1 
ATOM   5503 O  OP1   . C   C 2 35  ? 104.253 62.837  76.676  1.00 31.74 ? 35  C   C OP1   1 
ATOM   5504 O  OP2   . C   C 2 35  ? 106.064 63.540  78.348  1.00 31.74 ? 35  C   C OP2   1 
ATOM   5505 O  "O5'" . C   C 2 35  ? 106.439 63.758  75.896  1.00 31.74 ? 35  C   C "O5'" 1 
ATOM   5506 C  "C5'" . C   C 2 35  ? 106.081 63.685  74.524  1.00 31.74 ? 35  C   C "C5'" 1 
ATOM   5507 C  "C4'" . C   C 2 35  ? 107.314 63.725  73.653  1.00 31.74 ? 35  C   C "C4'" 1 
ATOM   5508 O  "O4'" . C   C 2 35  ? 108.092 64.904  73.987  1.00 31.74 ? 35  C   C "O4'" 1 
ATOM   5509 C  "C3'" . C   C 2 35  ? 108.251 62.542  73.870  1.00 31.74 ? 35  C   C "C3'" 1 
ATOM   5510 O  "O3'" . C   C 2 35  ? 108.039 61.492  72.938  1.00 31.74 ? 35  C   C "O3'" 1 
ATOM   5511 C  "C2'" . C   C 2 35  ? 109.645 63.136  73.687  1.00 31.74 ? 35  C   C "C2'" 1 
ATOM   5512 O  "O2'" . C   C 2 35  ? 110.014 63.105  72.317  1.00 31.74 ? 35  C   C "O2'" 1 
ATOM   5513 C  "C1'" . C   C 2 35  ? 109.460 64.589  74.098  1.00 31.74 ? 35  C   C "C1'" 1 
ATOM   5514 N  N1    . C   C 2 35  ? 109.933 64.897  75.474  1.00 31.74 ? 35  C   C N1    1 
ATOM   5515 C  C2    . C   C 2 35  ? 111.078 65.685  75.666  1.00 31.74 ? 35  C   C C2    1 
ATOM   5516 O  O2    . C   C 2 35  ? 111.729 66.115  74.712  1.00 31.74 ? 35  C   C O2    1 
ATOM   5517 N  N3    . C   C 2 35  ? 111.490 65.985  76.913  1.00 31.74 ? 35  C   C N3    1 
ATOM   5518 C  C4    . C   C 2 35  ? 110.817 65.530  77.959  1.00 31.74 ? 35  C   C C4    1 
ATOM   5519 N  N4    . C   C 2 35  ? 111.265 65.855  79.169  1.00 31.74 ? 35  C   C N4    1 
ATOM   5520 C  C5    . C   C 2 35  ? 109.643 64.745  77.812  1.00 31.74 ? 35  C   C C5    1 
ATOM   5521 C  C6    . C   C 2 35  ? 109.286 64.408  76.572  1.00 31.74 ? 35  C   C C6    1 
ATOM   5522 P  P     . G   C 2 36  ? 107.371 60.108  73.415  1.00 36.28 ? 36  G   C P     1 
ATOM   5523 O  OP1   . G   C 2 36  ? 107.380 59.176  72.259  1.00 36.28 ? 36  G   C OP1   1 
ATOM   5524 O  OP2   . G   C 2 36  ? 106.062 60.419  74.038  1.00 36.28 ? 36  G   C OP2   1 
ATOM   5525 O  "O5'" . G   C 2 36  ? 108.332 59.579  74.574  1.00 36.28 ? 36  G   C "O5'" 1 
ATOM   5526 C  "C5'" . G   C 2 36  ? 109.240 58.505  74.406  1.00 36.28 ? 36  G   C "C5'" 1 
ATOM   5527 C  "C4'" . G   C 2 36  ? 110.269 58.766  73.336  1.00 36.28 ? 36  G   C "C4'" 1 
ATOM   5528 O  "O4'" . G   C 2 36  ? 110.542 60.189  73.249  1.00 36.28 ? 36  G   C "O4'" 1 
ATOM   5529 C  "C3'" . G   C 2 36  ? 111.625 58.095  73.568  1.00 36.28 ? 36  G   C "C3'" 1 
ATOM   5530 O  "O3'" . G   C 2 36  ? 111.718 56.807  72.975  1.00 36.28 ? 36  G   C "O3'" 1 
ATOM   5531 C  "C2'" . G   C 2 36  ? 112.630 59.099  73.013  1.00 36.28 ? 36  G   C "C2'" 1 
ATOM   5532 O  "O2'" . G   C 2 36  ? 112.780 58.939  71.611  1.00 36.28 ? 36  G   C "O2'" 1 
ATOM   5533 C  "C1'" . G   C 2 36  ? 111.925 60.426  73.281  1.00 36.28 ? 36  G   C "C1'" 1 
ATOM   5534 N  N9    . G   C 2 36  ? 112.284 60.996  74.598  1.00 36.28 ? 36  G   C N9    1 
ATOM   5535 C  C8    . G   C 2 36  ? 111.680 60.779  75.814  1.00 36.28 ? 36  G   C C8    1 
ATOM   5536 N  N7    . G   C 2 36  ? 112.242 61.420  76.795  1.00 36.28 ? 36  G   C N7    1 
ATOM   5537 C  C5    . G   C 2 36  ? 113.259 62.132  76.184  1.00 36.28 ? 36  G   C C5    1 
ATOM   5538 C  C6    . G   C 2 36  ? 114.211 63.015  76.730  1.00 36.28 ? 36  G   C C6    1 
ATOM   5539 O  O6    . G   C 2 36  ? 114.356 63.343  77.904  1.00 36.28 ? 36  G   C O6    1 
ATOM   5540 N  N1    . G   C 2 36  ? 115.093 63.484  75.772  1.00 36.28 ? 36  G   C N1    1 
ATOM   5541 C  C2    . G   C 2 36  ? 115.044 63.175  74.443  1.00 36.28 ? 36  G   C C2    1 
ATOM   5542 N  N2    . G   C 2 36  ? 115.970 63.748  73.667  1.00 36.28 ? 36  G   C N2    1 
ATOM   5543 N  N3    . G   C 2 36  ? 114.158 62.359  73.916  1.00 36.28 ? 36  G   C N3    1 
ATOM   5544 C  C4    . G   C 2 36  ? 113.304 61.878  74.839  1.00 36.28 ? 36  G   C C4    1 
ATOM   5545 P  P     . DA  D 3 12  ? 62.248  111.181 130.669 1.00 47.18 ? -23 DA  D P     1 
ATOM   5546 O  OP1   . DA  D 3 12  ? 62.663  111.369 132.073 1.00 47.18 ? -23 DA  D OP1   1 
ATOM   5547 O  OP2   . DA  D 3 12  ? 61.481  112.272 130.033 1.00 47.18 ? -23 DA  D OP2   1 
ATOM   5548 O  "O5'" . DA  D 3 12  ? 63.550  110.956 129.769 1.00 47.18 ? -23 DA  D "O5'" 1 
ATOM   5549 C  "C5'" . DA  D 3 12  ? 64.570  111.957 129.690 1.00 47.18 ? -23 DA  D "C5'" 1 
ATOM   5550 C  "C4'" . DA  D 3 12  ? 65.673  111.519 128.739 1.00 47.18 ? -23 DA  D "C4'" 1 
ATOM   5551 O  "O4'" . DA  D 3 12  ? 66.262  110.263 129.209 1.00 47.18 ? -23 DA  D "O4'" 1 
ATOM   5552 C  "C3'" . DA  D 3 12  ? 65.175  111.239 127.308 1.00 47.18 ? -23 DA  D "C3'" 1 
ATOM   5553 O  "O3'" . DA  D 3 12  ? 66.134  111.622 126.342 1.00 47.18 ? -23 DA  D "O3'" 1 
ATOM   5554 C  "C2'" . DA  D 3 12  ? 65.066  109.726 127.275 1.00 47.18 ? -23 DA  D "C2'" 1 
ATOM   5555 C  "C1'" . DA  D 3 12  ? 66.269  109.372 128.124 1.00 47.18 ? -23 DA  D "C1'" 1 
ATOM   5556 N  N9    . DA  D 3 12  ? 66.361  107.963 128.512 1.00 47.18 ? -23 DA  D N9    1 
ATOM   5557 C  C8    . DA  D 3 12  ? 65.345  107.052 128.545 1.00 47.18 ? -23 DA  D C8    1 
ATOM   5558 N  N7    . DA  D 3 12  ? 65.734  105.834 128.836 1.00 47.18 ? -23 DA  D N7    1 
ATOM   5559 C  C5    . DA  D 3 12  ? 67.110  105.939 128.940 1.00 47.18 ? -23 DA  D C5    1 
ATOM   5560 C  C6    . DA  D 3 12  ? 68.117  104.993 129.225 1.00 47.18 ? -23 DA  D C6    1 
ATOM   5561 N  N6    . DA  D 3 12  ? 67.863  103.707 129.462 1.00 47.18 ? -23 DA  D N6    1 
ATOM   5562 N  N1    . DA  D 3 12  ? 69.397  105.425 129.255 1.00 47.18 ? -23 DA  D N1    1 
ATOM   5563 C  C2    . DA  D 3 12  ? 69.643  106.721 129.015 1.00 47.18 ? -23 DA  D C2    1 
ATOM   5564 N  N3    . DA  D 3 12  ? 68.780  107.702 128.740 1.00 47.18 ? -23 DA  D N3    1 
ATOM   5565 C  C4    . DA  D 3 12  ? 67.518  107.240 128.718 1.00 47.18 ? -23 DA  D C4    1 
ATOM   5566 P  P     . DA  D 3 13  ? 66.111  113.054 125.621 1.00 46.70 ? -22 DA  D P     1 
ATOM   5567 O  OP1   . DA  D 3 13  ? 65.776  114.089 126.623 1.00 46.70 ? -22 DA  D OP1   1 
ATOM   5568 O  OP2   . DA  D 3 13  ? 65.288  112.920 124.399 1.00 46.70 ? -22 DA  D OP2   1 
ATOM   5569 O  "O5'" . DA  D 3 13  ? 67.635  113.221 125.170 1.00 46.70 ? -22 DA  D "O5'" 1 
ATOM   5570 C  "C5'" . DA  D 3 13  ? 68.613  113.674 126.093 1.00 46.70 ? -22 DA  D "C5'" 1 
ATOM   5571 C  "C4'" . DA  D 3 13  ? 70.011  113.213 125.688 1.00 46.70 ? -22 DA  D "C4'" 1 
ATOM   5572 O  "O4'" . DA  D 3 13  ? 70.241  111.833 126.081 1.00 46.70 ? -22 DA  D "O4'" 1 
ATOM   5573 C  "C3'" . DA  D 3 13  ? 70.307  113.288 124.191 1.00 46.70 ? -22 DA  D "C3'" 1 
ATOM   5574 O  "O3'" . DA  D 3 13  ? 71.634  113.778 123.997 1.00 46.70 ? -22 DA  D "O3'" 1 
ATOM   5575 C  "C2'" . DA  D 3 13  ? 70.116  111.842 123.719 1.00 46.70 ? -22 DA  D "C2'" 1 
ATOM   5576 C  "C1'" . DA  D 3 13  ? 70.507  111.031 124.947 1.00 46.70 ? -22 DA  D "C1'" 1 
ATOM   5577 N  N9    . DA  D 3 13  ? 69.770  109.770 125.091 1.00 46.70 ? -22 DA  D N9    1 
ATOM   5578 C  C8    . DA  D 3 13  ? 68.422  109.589 124.961 1.00 46.70 ? -22 DA  D C8    1 
ATOM   5579 N  N7    . DA  D 3 13  ? 68.031  108.352 125.147 1.00 46.70 ? -22 DA  D N7    1 
ATOM   5580 C  C5    . DA  D 3 13  ? 69.204  107.668 125.407 1.00 46.70 ? -22 DA  D C5    1 
ATOM   5581 C  C6    . DA  D 3 13  ? 69.466  106.310 125.689 1.00 46.70 ? -22 DA  D C6    1 
ATOM   5582 N  N6    . DA  D 3 13  ? 68.513  105.379 125.749 1.00 46.70 ? -22 DA  D N6    1 
ATOM   5583 N  N1    . DA  D 3 13  ? 70.743  105.951 125.906 1.00 46.70 ? -22 DA  D N1    1 
ATOM   5584 C  C2    . DA  D 3 13  ? 71.698  106.890 125.841 1.00 46.70 ? -22 DA  D C2    1 
ATOM   5585 N  N3    . DA  D 3 13  ? 71.575  108.195 125.587 1.00 46.70 ? -22 DA  D N3    1 
ATOM   5586 C  C4    . DA  D 3 13  ? 70.288  108.523 125.376 1.00 46.70 ? -22 DA  D C4    1 
ATOM   5587 P  P     . DA  D 3 14  ? 72.317  113.824 122.543 1.00 40.90 ? -21 DA  D P     1 
ATOM   5588 O  OP1   . DA  D 3 14  ? 73.117  115.070 122.462 1.00 40.90 ? -21 DA  D OP1   1 
ATOM   5589 O  OP2   . DA  D 3 14  ? 71.284  113.574 121.515 1.00 40.90 ? -21 DA  D OP2   1 
ATOM   5590 O  "O5'" . DA  D 3 14  ? 73.320  112.577 122.567 1.00 40.90 ? -21 DA  D "O5'" 1 
ATOM   5591 C  "C5'" . DA  D 3 14  ? 74.461  112.613 123.434 1.00 40.90 ? -21 DA  D "C5'" 1 
ATOM   5592 C  "C4'" . DA  D 3 14  ? 75.450  111.486 123.127 1.00 40.90 ? -21 DA  D "C4'" 1 
ATOM   5593 O  "O4'" . DA  D 3 14  ? 74.846  110.183 123.342 1.00 40.90 ? -21 DA  D "O4'" 1 
ATOM   5594 C  "C3'" . DA  D 3 14  ? 75.984  111.471 121.704 1.00 40.90 ? -21 DA  D "C3'" 1 
ATOM   5595 O  "O3'" . DA  D 3 14  ? 77.363  111.080 121.730 1.00 40.90 ? -21 DA  D "O3'" 1 
ATOM   5596 C  "C2'" . DA  D 3 14  ? 75.065  110.476 120.989 1.00 40.90 ? -21 DA  D "C2'" 1 
ATOM   5597 C  "C1'" . DA  D 3 14  ? 74.675  109.515 122.106 1.00 40.90 ? -21 DA  D "C1'" 1 
ATOM   5598 N  N9    . DA  D 3 14  ? 73.302  109.019 122.041 1.00 40.90 ? -21 DA  D N9    1 
ATOM   5599 C  C8    . DA  D 3 14  ? 72.187  109.720 121.694 1.00 40.90 ? -21 DA  D C8    1 
ATOM   5600 N  N7    . DA  D 3 14  ? 71.086  109.009 121.712 1.00 40.90 ? -21 DA  D N7    1 
ATOM   5601 C  C5    . DA  D 3 14  ? 71.519  107.735 122.043 1.00 40.90 ? -21 DA  D C5    1 
ATOM   5602 C  C6    . DA  D 3 14  ? 70.839  106.510 122.210 1.00 40.90 ? -21 DA  D C6    1 
ATOM   5603 N  N6    . DA  D 3 14  ? 69.523  106.377 122.057 1.00 40.90 ? -21 DA  D N6    1 
ATOM   5604 N  N1    . DA  D 3 14  ? 71.565  105.429 122.546 1.00 40.90 ? -21 DA  D N1    1 
ATOM   5605 C  C2    . DA  D 3 14  ? 72.887  105.568 122.700 1.00 40.90 ? -21 DA  D C2    1 
ATOM   5606 N  N3    . DA  D 3 14  ? 73.637  106.665 122.572 1.00 40.90 ? -21 DA  D N3    1 
ATOM   5607 C  C4    . DA  D 3 14  ? 72.884  107.721 122.237 1.00 40.90 ? -21 DA  D C4    1 
ATOM   5608 P  P     . DT  D 3 15  ? 78.202  110.767 120.391 1.00 31.36 ? -20 DT  D P     1 
ATOM   5609 O  OP1   . DT  D 3 15  ? 79.635  110.938 120.696 1.00 31.36 ? -20 DT  D OP1   1 
ATOM   5610 O  OP2   . DT  D 3 15  ? 77.606  111.500 119.258 1.00 31.36 ? -20 DT  D OP2   1 
ATOM   5611 O  "O5'" . DT  D 3 15  ? 77.979  109.214 120.140 1.00 31.36 ? -20 DT  D "O5'" 1 
ATOM   5612 C  "C5'" . DT  D 3 15  ? 78.489  108.273 121.069 1.00 31.36 ? -20 DT  D "C5'" 1 
ATOM   5613 C  "C4'" . DT  D 3 15  ? 78.089  106.879 120.656 1.00 31.36 ? -20 DT  D "C4'" 1 
ATOM   5614 O  "O4'" . DT  D 3 15  ? 76.654  106.743 120.647 1.00 31.36 ? -20 DT  D "O4'" 1 
ATOM   5615 C  "C3'" . DT  D 3 15  ? 78.559  106.494 119.258 1.00 31.36 ? -20 DT  D "C3'" 1 
ATOM   5616 O  "O3'" . DT  D 3 15  ? 79.526  105.463 119.373 1.00 31.36 ? -20 DT  D "O3'" 1 
ATOM   5617 C  "C2'" . DT  D 3 15  ? 77.290  106.066 118.504 1.00 31.36 ? -20 DT  D "C2'" 1 
ATOM   5618 C  "C1'" . DT  D 3 15  ? 76.298  105.840 119.631 1.00 31.36 ? -20 DT  D "C1'" 1 
ATOM   5619 N  N1    . DT  D 3 15  ? 74.856  106.084 119.286 1.00 31.36 ? -20 DT  D N1    1 
ATOM   5620 C  C2    . DT  D 3 15  ? 73.945  105.056 119.415 1.00 31.36 ? -20 DT  D C2    1 
ATOM   5621 O  O2    . DT  D 3 15  ? 74.265  103.916 119.692 1.00 31.36 ? -20 DT  D O2    1 
ATOM   5622 N  N3    . DT  D 3 15  ? 72.647  105.405 119.135 1.00 31.36 ? -20 DT  D N3    1 
ATOM   5623 C  C4    . DT  D 3 15  ? 72.178  106.653 118.791 1.00 31.36 ? -20 DT  D C4    1 
ATOM   5624 O  O4    . DT  D 3 15  ? 70.994  106.867 118.563 1.00 31.36 ? -20 DT  D O4    1 
ATOM   5625 C  C5    . DT  D 3 15  ? 73.179  107.690 118.718 1.00 31.36 ? -20 DT  D C5    1 
ATOM   5626 C  C7    . DT  D 3 15  ? 72.788  109.096 118.355 1.00 31.36 ? -20 DT  D C7    1 
ATOM   5627 C  C6    . DT  D 3 15  ? 74.451  107.360 118.987 1.00 31.36 ? -20 DT  D C6    1 
ATOM   5628 P  P     . DT  D 3 16  ? 80.264  104.860 118.085 1.00 17.14 ? -19 DT  D P     1 
ATOM   5629 O  OP1   . DT  D 3 16  ? 81.557  104.306 118.534 1.00 17.14 ? -19 DT  D OP1   1 
ATOM   5630 O  OP2   . DT  D 3 16  ? 80.233  105.897 117.033 1.00 17.14 ? -19 DT  D OP2   1 
ATOM   5631 O  "O5'" . DT  D 3 16  ? 79.315  103.662 117.621 1.00 17.14 ? -19 DT  D "O5'" 1 
ATOM   5632 C  "C5'" . DT  D 3 16  ? 79.052  102.594 118.527 1.00 17.14 ? -19 DT  D "C5'" 1 
ATOM   5633 C  "C4'" . DT  D 3 16  ? 77.862  101.751 118.088 1.00 17.14 ? -19 DT  D "C4'" 1 
ATOM   5634 O  "O4'" . DT  D 3 16  ? 76.649  102.540 117.970 1.00 17.14 ? -19 DT  D "O4'" 1 
ATOM   5635 C  "C3'" . DT  D 3 16  ? 78.050  101.059 116.737 1.00 17.14 ? -19 DT  D "C3'" 1 
ATOM   5636 O  "O3'" . DT  D 3 16  ? 77.841  99.665  116.917 1.00 17.14 ? -19 DT  D "O3'" 1 
ATOM   5637 C  "C2'" . DT  D 3 16  ? 77.002  101.733 115.836 1.00 17.14 ? -19 DT  D "C2'" 1 
ATOM   5638 C  "C1'" . DT  D 3 16  ? 75.938  102.067 116.848 1.00 17.14 ? -19 DT  D "C1'" 1 
ATOM   5639 N  N1    . DT  D 3 16  ? 74.965  103.123 116.428 1.00 17.14 ? -19 DT  D N1    1 
ATOM   5640 C  C2    . DT  D 3 16  ? 73.624  102.836 116.401 1.00 17.14 ? -19 DT  D C2    1 
ATOM   5641 O  O2    . DT  D 3 16  ? 73.184  101.722 116.593 1.00 17.14 ? -19 DT  D O2    1 
ATOM   5642 N  N3    . DT  D 3 16  ? 72.821  103.888 116.048 1.00 17.14 ? -19 DT  D N3    1 
ATOM   5643 C  C4    . DT  D 3 16  ? 73.215  105.183 115.784 1.00 17.14 ? -19 DT  D C4    1 
ATOM   5644 O  O4    . DT  D 3 16  ? 72.420  106.062 115.493 1.00 17.14 ? -19 DT  D O4    1 
ATOM   5645 C  C5    . DT  D 3 16  ? 74.630  105.426 115.886 1.00 17.14 ? -19 DT  D C5    1 
ATOM   5646 C  C7    . DT  D 3 16  ? 75.184  106.789 115.622 1.00 17.14 ? -19 DT  D C7    1 
ATOM   5647 C  C6    . DT  D 3 16  ? 75.420  104.402 116.212 1.00 17.14 ? -19 DT  D C6    1 
ATOM   5648 P  P     . DG  D 3 17  ? 78.094  98.611  115.737 1.00 5.06  ? -18 DG  D P     1 
ATOM   5649 O  OP1   . DG  D 3 17  ? 79.009  97.577  116.269 1.00 5.06  ? -18 DG  D OP1   1 
ATOM   5650 O  OP2   . DG  D 3 17  ? 78.435  99.329  114.489 1.00 5.06  ? -18 DG  D OP2   1 
ATOM   5651 O  "O5'" . DG  D 3 17  ? 76.680  97.917  115.555 1.00 5.06  ? -18 DG  D "O5'" 1 
ATOM   5652 C  "C5'" . DG  D 3 17  ? 75.524  98.680  115.390 1.00 5.06  ? -18 DG  D "C5'" 1 
ATOM   5653 C  "C4'" . DG  D 3 17  ? 74.397  97.774  114.987 1.00 5.06  ? -18 DG  D "C4'" 1 
ATOM   5654 O  "O4'" . DG  D 3 17  ? 73.184  98.539  114.796 1.00 5.06  ? -18 DG  D "O4'" 1 
ATOM   5655 C  "C3'" . DG  D 3 17  ? 74.640  97.112  113.659 1.00 5.06  ? -18 DG  D "C3'" 1 
ATOM   5656 O  "O3'" . DG  D 3 17  ? 73.910  95.905  113.599 1.00 5.06  ? -18 DG  D "O3'" 1 
ATOM   5657 C  "C2'" . DG  D 3 17  ? 74.174  98.189  112.671 1.00 5.06  ? -18 DG  D "C2'" 1 
ATOM   5658 C  "C1'" . DG  D 3 17  ? 73.011  98.822  113.418 1.00 5.06  ? -18 DG  D "C1'" 1 
ATOM   5659 N  N9    . DG  D 3 17  ? 72.889  100.265 113.276 1.00 5.06  ? -18 DG  D N9    1 
ATOM   5660 C  C8    . DG  D 3 17  ? 73.890  101.202 113.340 1.00 5.06  ? -18 DG  D C8    1 
ATOM   5661 N  N7    . DG  D 3 17  ? 73.464  102.423 113.189 1.00 5.06  ? -18 DG  D N7    1 
ATOM   5662 C  C5    . DG  D 3 17  ? 72.103  102.280 112.976 1.00 5.06  ? -18 DG  D C5    1 
ATOM   5663 C  C6    . DG  D 3 17  ? 71.116  103.252 112.722 1.00 5.06  ? -18 DG  D C6    1 
ATOM   5664 O  O6    . DG  D 3 17  ? 71.253  104.472 112.642 1.00 5.06  ? -18 DG  D O6    1 
ATOM   5665 N  N1    . DG  D 3 17  ? 69.864  102.681 112.555 1.00 5.06  ? -18 DG  D N1    1 
ATOM   5666 C  C2    . DG  D 3 17  ? 69.600  101.341 112.625 1.00 5.06  ? -18 DG  D C2    1 
ATOM   5667 N  N2    . DG  D 3 17  ? 68.331  100.975 112.440 1.00 5.06  ? -18 DG  D N2    1 
ATOM   5668 N  N3    . DG  D 3 17  ? 70.514  100.419 112.860 1.00 5.06  ? -18 DG  D N3    1 
ATOM   5669 C  C4    . DG  D 3 17  ? 71.738  100.960 113.024 1.00 5.06  ? -18 DG  D C4    1 
ATOM   5670 P  P     . DA  D 3 18  ? 73.857  95.053  112.249 1.00 1.51  ? -17 DA  D P     1 
ATOM   5671 O  OP1   . DA  D 3 18  ? 73.625  93.634  112.600 1.00 1.51  ? -17 DA  D OP1   1 
ATOM   5672 O  OP2   . DA  D 3 18  ? 75.055  95.405  111.460 1.00 1.51  ? -17 DA  D OP2   1 
ATOM   5673 O  "O5'" . DA  D 3 18  ? 72.546  95.599  111.519 1.00 1.51  ? -17 DA  D "O5'" 1 
ATOM   5674 C  "C5'" . DA  D 3 18  ? 71.273  95.426  112.143 1.00 1.51  ? -17 DA  D "C5'" 1 
ATOM   5675 C  "C4'" . DA  D 3 18  ? 70.171  96.047  111.310 1.00 1.51  ? -17 DA  D "C4'" 1 
ATOM   5676 O  "O4'" . DA  D 3 18  ? 70.387  97.454  111.166 1.00 1.51  ? -17 DA  D "O4'" 1 
ATOM   5677 C  "C3'" . DA  D 3 18  ? 70.059  95.487  109.907 1.00 1.51  ? -17 DA  D "C3'" 1 
ATOM   5678 O  "O3'" . DA  D 3 18  ? 68.689  95.208  109.668 1.00 1.51  ? -17 DA  D "O3'" 1 
ATOM   5679 C  "C2'" . DA  D 3 18  ? 70.633  96.605  109.005 1.00 1.51  ? -17 DA  D "C2'" 1 
ATOM   5680 C  "C1'" . DA  D 3 18  ? 70.261  97.829  109.814 1.00 1.51  ? -17 DA  D "C1'" 1 
ATOM   5681 N  N9    . DA  D 3 18  ? 71.070  99.026  109.687 1.00 1.51  ? -17 DA  D N9    1 
ATOM   5682 C  C8    . DA  D 3 18  ? 72.411  99.154  109.886 1.00 1.51  ? -17 DA  D C8    1 
ATOM   5683 N  N7    . DA  D 3 18  ? 72.834  100.394 109.825 1.00 1.51  ? -17 DA  D N7    1 
ATOM   5684 C  C5    . DA  D 3 18  ? 71.681  101.120 109.588 1.00 1.51  ? -17 DA  D C5    1 
ATOM   5685 C  C6    . DA  D 3 18  ? 71.435  102.488 109.412 1.00 1.51  ? -17 DA  D C6    1 
ATOM   5686 N  N6    . DA  D 3 18  ? 72.382  103.418 109.456 1.00 1.51  ? -17 DA  D N6    1 
ATOM   5687 N  N1    . DA  D 3 18  ? 70.168  102.871 109.207 1.00 1.51  ? -17 DA  D N1    1 
ATOM   5688 C  C2    . DA  D 3 18  ? 69.226  101.946 109.168 1.00 1.51  ? -17 DA  D C2    1 
ATOM   5689 N  N3    . DA  D 3 18  ? 69.331  100.643 109.318 1.00 1.51  ? -17 DA  D N3    1 
ATOM   5690 C  C4    . DA  D 3 18  ? 70.595  100.290 109.523 1.00 1.51  ? -17 DA  D C4    1 
ATOM   5691 P  P     . DT  D 3 19  ? 68.214  94.307  108.436 1.00 1.41  ? -16 DT  D P     1 
ATOM   5692 O  OP1   . DT  D 3 19  ? 66.964  93.610  108.810 1.00 1.41  ? -16 DT  D OP1   1 
ATOM   5693 O  OP2   . DT  D 3 19  ? 69.369  93.514  107.973 1.00 1.41  ? -16 DT  D OP2   1 
ATOM   5694 O  "O5'" . DT  D 3 19  ? 67.893  95.393  107.324 1.00 1.41  ? -16 DT  D "O5'" 1 
ATOM   5695 C  "C5'" . DT  D 3 19  ? 66.684  96.121  107.363 1.00 1.41  ? -16 DT  D "C5'" 1 
ATOM   5696 C  "C4'" . DT  D 3 19  ? 66.670  97.095  106.221 1.00 1.41  ? -16 DT  D "C4'" 1 
ATOM   5697 O  "O4'" . DT  D 3 19  ? 67.576  98.197  106.473 1.00 1.41  ? -16 DT  D "O4'" 1 
ATOM   5698 C  "C3'" . DT  D 3 19  ? 67.111  96.460  104.909 1.00 1.41  ? -16 DT  D "C3'" 1 
ATOM   5699 O  "O3'" . DT  D 3 19  ? 66.364  96.976  103.841 1.00 1.41  ? -16 DT  D "O3'" 1 
ATOM   5700 C  "C2'" . DT  D 3 19  ? 68.561  96.933  104.787 1.00 1.41  ? -16 DT  D "C2'" 1 
ATOM   5701 C  "C1'" . DT  D 3 19  ? 68.406  98.325  105.355 1.00 1.41  ? -16 DT  D "C1'" 1 
ATOM   5702 N  N1    . DT  D 3 19  ? 69.651  99.058  105.672 1.00 1.41  ? -16 DT  D N1    1 
ATOM   5703 C  C2    . DT  D 3 19  ? 69.599  100.424 105.687 1.00 1.41  ? -16 DT  D C2    1 
ATOM   5704 O  O2    . DT  D 3 19  ? 68.584  101.049 105.457 1.00 1.41  ? -16 DT  D O2    1 
ATOM   5705 N  N3    . DT  D 3 19  ? 70.774  101.042 105.953 1.00 1.41  ? -16 DT  D N3    1 
ATOM   5706 C  C4    . DT  D 3 19  ? 71.977  100.458 106.218 1.00 1.41  ? -16 DT  D C4    1 
ATOM   5707 O  O4    . DT  D 3 19  ? 72.980  101.125 106.450 1.00 1.41  ? -16 DT  D O4    1 
ATOM   5708 C  C5    . DT  D 3 19  ? 71.978  99.008  106.188 1.00 1.41  ? -16 DT  D C5    1 
ATOM   5709 C  C7    . DT  D 3 19  ? 73.236  98.252  106.451 1.00 1.41  ? -16 DT  D C7    1 
ATOM   5710 C  C6    . DT  D 3 19  ? 70.822  98.382  105.915 1.00 1.41  ? -16 DT  D C6    1 
ATOM   5711 P  P     . DG  D 3 20  ? 65.017  96.274  103.337 1.00 2.37  ? -15 DG  D P     1 
ATOM   5712 O  OP1   . DG  D 3 20  ? 64.232  95.832  104.504 1.00 2.37  ? -15 DG  D OP1   1 
ATOM   5713 O  OP2   . DG  D 3 20  ? 65.362  95.315  102.271 1.00 2.37  ? -15 DG  D OP2   1 
ATOM   5714 O  "O5'" . DG  D 3 20  ? 64.266  97.490  102.654 1.00 2.37  ? -15 DG  D "O5'" 1 
ATOM   5715 C  "C5'" . DG  D 3 20  ? 63.568  98.440  103.420 1.00 2.37  ? -15 DG  D "C5'" 1 
ATOM   5716 C  "C4'" . DG  D 3 20  ? 63.683  99.797  102.757 1.00 2.37  ? -15 DG  D "C4'" 1 
ATOM   5717 O  "O4'" . DG  D 3 20  ? 64.973  100.415 103.014 1.00 2.37  ? -15 DG  D "O4'" 1 
ATOM   5718 C  "C3'" . DG  D 3 20  ? 63.506  99.785  101.254 1.00 2.37  ? -15 DG  D "C3'" 1 
ATOM   5719 O  "O3'" . DG  D 3 20  ? 62.767  100.951 100.908 1.00 2.37  ? -15 DG  D "O3'" 1 
ATOM   5720 C  "C2'" . DG  D 3 20  ? 64.961  99.799  100.745 1.00 2.37  ? -15 DG  D "C2'" 1 
ATOM   5721 C  "C1'" . DG  D 3 20  ? 65.637  100.682 101.787 1.00 2.37  ? -15 DG  D "C1'" 1 
ATOM   5722 N  N9    . DG  D 3 20  ? 67.061  100.432 102.026 1.00 2.37  ? -15 DG  D N9    1 
ATOM   5723 C  C8    . DG  D 3 20  ? 67.668  99.217  102.176 1.00 2.37  ? -15 DG  D C8    1 
ATOM   5724 N  N7    . DG  D 3 20  ? 68.944  99.299  102.413 1.00 2.37  ? -15 DG  D N7    1 
ATOM   5725 C  C5    . DG  D 3 20  ? 69.205  100.653 102.409 1.00 2.37  ? -15 DG  D C5    1 
ATOM   5726 C  C6    . DG  D 3 20  ? 70.422  101.339 102.590 1.00 2.37  ? -15 DG  D C6    1 
ATOM   5727 O  O6    . DG  D 3 20  ? 71.537  100.865 102.816 1.00 2.37  ? -15 DG  D O6    1 
ATOM   5728 N  N1    . DG  D 3 20  ? 70.261  102.708 102.494 1.00 2.37  ? -15 DG  D N1    1 
ATOM   5729 C  C2    . DG  D 3 20  ? 69.073  103.335 102.261 1.00 2.37  ? -15 DG  D C2    1 
ATOM   5730 N  N2    . DG  D 3 20  ? 69.116  104.664 102.203 1.00 2.37  ? -15 DG  D N2    1 
ATOM   5731 N  N3    . DG  D 3 20  ? 67.923  102.708 102.081 1.00 2.37  ? -15 DG  D N3    1 
ATOM   5732 C  C4    . DG  D 3 20  ? 68.063  101.368 102.168 1.00 2.37  ? -15 DG  D C4    1 
ATOM   5733 P  P     . DA  D 3 21  ? 62.188  101.199 99.436  1.00 2.37  ? -14 DA  D P     1 
ATOM   5734 O  OP1   . DA  D 3 21  ? 60.742  101.440 99.577  1.00 2.37  ? -14 DA  D OP1   1 
ATOM   5735 O  OP2   . DA  D 3 21  ? 62.664  100.136 98.532  1.00 2.37  ? -14 DA  D OP2   1 
ATOM   5736 O  "O5'" . DA  D 3 21  ? 62.838  102.581 99.003  1.00 2.37  ? -14 DA  D "O5'" 1 
ATOM   5737 C  "C5'" . DA  D 3 21  ? 64.213  102.827 99.192  1.00 2.37  ? -14 DA  D "C5'" 1 
ATOM   5738 C  "C4'" . DA  D 3 21  ? 64.588  104.110 98.497  1.00 2.37  ? -14 DA  D "C4'" 1 
ATOM   5739 O  "O4'" . DA  D 3 21  ? 65.935  104.483 98.873  1.00 2.37  ? -14 DA  D "O4'" 1 
ATOM   5740 C  "C3'" . DA  D 3 21  ? 64.569  103.965 96.984  1.00 2.37  ? -14 DA  D "C3'" 1 
ATOM   5741 O  "O3'" . DA  D 3 21  ? 63.933  105.104 96.388  1.00 2.37  ? -14 DA  D "O3'" 1 
ATOM   5742 C  "C2'" . DA  D 3 21  ? 66.046  103.863 96.575  1.00 2.37  ? -14 DA  D "C2'" 1 
ATOM   5743 C  "C1'" . DA  D 3 21  ? 66.840  104.164 97.845  1.00 2.37  ? -14 DA  D "C1'" 1 
ATOM   5744 N  N9    . DA  D 3 21  ? 67.779  103.108 98.264  1.00 2.37  ? -14 DA  D N9    1 
ATOM   5745 C  C8    . DA  D 3 21  ? 67.573  101.764 98.257  1.00 2.37  ? -14 DA  D C8    1 
ATOM   5746 N  N7    . DA  D 3 21  ? 68.617  101.072 98.643  1.00 2.37  ? -14 DA  D N7    1 
ATOM   5747 C  C5    . DA  D 3 21  ? 69.586  102.027 98.894  1.00 2.37  ? -14 DA  D C5    1 
ATOM   5748 C  C6    . DA  D 3 21  ? 70.928  101.939 99.329  1.00 2.37  ? -14 DA  D C6    1 
ATOM   5749 N  N6    . DA  D 3 21  ? 71.542  100.788 99.598  1.00 2.37  ? -14 DA  D N6    1 
ATOM   5750 N  N1    . DA  D 3 21  ? 71.620  103.082 99.470  1.00 2.37  ? -14 DA  D N1    1 
ATOM   5751 C  C2    . DA  D 3 21  ? 71.005  104.233 99.205  1.00 2.37  ? -14 DA  D C2    1 
ATOM   5752 N  N3    . DA  D 3 21  ? 69.761  104.440 98.781  1.00 2.37  ? -14 DA  D N3    1 
ATOM   5753 C  C4    . DA  D 3 21  ? 69.097  103.281 98.647  1.00 2.37  ? -14 DA  D C4    1 
ATOM   5754 P  P     . DT  D 3 22  ? 63.107  104.971 95.014  1.00 7.25  ? -13 DT  D P     1 
ATOM   5755 O  OP1   . DT  D 3 22  ? 62.197  106.126 94.943  1.00 7.25  ? -13 DT  D OP1   1 
ATOM   5756 O  OP2   . DT  D 3 22  ? 62.588  103.589 94.964  1.00 7.25  ? -13 DT  D OP2   1 
ATOM   5757 O  "O5'" . DT  D 3 22  ? 64.158  105.094 93.818  1.00 7.25  ? -13 DT  D "O5'" 1 
ATOM   5758 C  "C5'" . DT  D 3 22  ? 64.912  103.974 93.433  1.00 7.25  ? -13 DT  D "C5'" 1 
ATOM   5759 C  "C4'" . DT  D 3 22  ? 65.892  104.326 92.337  1.00 7.25  ? -13 DT  D "C4'" 1 
ATOM   5760 O  "O4'" . DT  D 3 22  ? 67.192  103.807 92.645  1.00 7.25  ? -13 DT  D "O4'" 1 
ATOM   5761 C  "C3'" . DT  D 3 22  ? 65.508  103.715 91.008  1.00 7.25  ? -13 DT  D "C3'" 1 
ATOM   5762 O  "O3'" . DT  D 3 22  ? 65.813  104.596 89.923  1.00 7.25  ? -13 DT  D "O3'" 1 
ATOM   5763 C  "C2'" . DT  D 3 22  ? 66.293  102.391 90.972  1.00 7.25  ? -13 DT  D "C2'" 1 
ATOM   5764 C  "C1'" . DT  D 3 22  ? 67.453  102.616 91.944  1.00 7.25  ? -13 DT  D "C1'" 1 
ATOM   5765 N  N1    . DT  D 3 22  ? 67.647  101.542 92.942  1.00 7.25  ? -13 DT  D N1    1 
ATOM   5766 C  C2    . DT  D 3 22  ? 68.919  101.147 93.258  1.00 7.25  ? -13 DT  D C2    1 
ATOM   5767 O  O2    . DT  D 3 22  ? 69.907  101.651 92.779  1.00 7.25  ? -13 DT  D O2    1 
ATOM   5768 N  N3    . DT  D 3 22  ? 68.999  100.164 94.195  1.00 7.25  ? -13 DT  D N3    1 
ATOM   5769 C  C4    . DT  D 3 22  ? 67.954  99.517  94.811  1.00 7.25  ? -13 DT  D C4    1 
ATOM   5770 O  O4    . DT  D 3 22  ? 68.129  98.636  95.638  1.00 7.25  ? -13 DT  D O4    1 
ATOM   5771 C  C5    . DT  D 3 22  ? 66.643  99.959  94.420  1.00 7.25  ? -13 DT  D C5    1 
ATOM   5772 C  C7    . DT  D 3 22  ? 65.423  99.338  95.025  1.00 7.25  ? -13 DT  D C7    1 
ATOM   5773 C  C6    . DT  D 3 22  ? 66.555  100.938 93.510  1.00 7.25  ? -13 DT  D C6    1 
ATOM   5774 P  P     . DT  D 3 23  ? 65.357  104.201 88.437  1.00 7.40  ? -12 DT  D P     1 
ATOM   5775 O  OP1   . DT  D 3 23  ? 65.207  105.434 87.656  1.00 7.40  ? -12 DT  D OP1   1 
ATOM   5776 O  OP2   . DT  D 3 23  ? 64.212  103.293 88.599  1.00 7.40  ? -12 DT  D OP2   1 
ATOM   5777 O  "O5'" . DT  D 3 23  ? 66.567  103.352 87.838  1.00 7.40  ? -12 DT  D "O5'" 1 
ATOM   5778 C  "C5'" . DT  D 3 23  ? 67.808  103.983 87.503  1.00 7.40  ? -12 DT  D "C5'" 1 
ATOM   5779 C  "C4'" . DT  D 3 23  ? 68.895  102.938 87.274  1.00 7.40  ? -12 DT  D "C4'" 1 
ATOM   5780 O  "O4'" . DT  D 3 23  ? 69.159  102.259 88.494  1.00 7.40  ? -12 DT  D "O4'" 1 
ATOM   5781 C  "C3'" . DT  D 3 23  ? 68.526  101.847 86.306  1.00 7.40  ? -12 DT  D "C3'" 1 
ATOM   5782 O  "O3'" . DT  D 3 23  ? 68.877  102.224 84.982  1.00 7.40  ? -12 DT  D "O3'" 1 
ATOM   5783 C  "C2'" . DT  D 3 23  ? 69.354  100.643 86.791  1.00 7.40  ? -12 DT  D "C2'" 1 
ATOM   5784 C  "C1'" . DT  D 3 23  ? 69.718  101.003 88.235  1.00 7.40  ? -12 DT  D "C1'" 1 
ATOM   5785 N  N1    . DT  D 3 23  ? 69.211  100.072 89.256  1.00 7.40  ? -12 DT  D N1    1 
ATOM   5786 C  C2    . DT  D 3 23  ? 70.107  99.463  90.085  1.00 7.40  ? -12 DT  D C2    1 
ATOM   5787 O  O2    . DT  D 3 23  ? 71.297  99.695  90.055  1.00 7.40  ? -12 DT  D O2    1 
ATOM   5788 N  N3    . DT  D 3 23  ? 69.562  98.631  91.011  1.00 7.40  ? -12 DT  D N3    1 
ATOM   5789 C  C4    . DT  D 3 23  ? 68.238  98.306  91.155  1.00 7.40  ? -12 DT  D C4    1 
ATOM   5790 O  O4    . DT  D 3 23  ? 67.850  97.525  92.014  1.00 7.40  ? -12 DT  D O4    1 
ATOM   5791 C  C5    . DT  D 3 23  ? 67.340  98.950  90.225  1.00 7.40  ? -12 DT  D C5    1 
ATOM   5792 C  C7    . DT  D 3 23  ? 65.869  98.675  90.284  1.00 7.40  ? -12 DT  D C7    1 
ATOM   5793 C  C6    . DT  D 3 23  ? 67.868  99.790  89.323  1.00 7.40  ? -12 DT  D C6    1 
ATOM   5794 P  P     . DG  D 3 24  ? 67.829  101.970 83.800  1.00 14.56 ? -11 DG  D P     1 
ATOM   5795 O  OP1   . DG  D 3 24  ? 68.366  102.542 82.555  1.00 14.56 ? -11 DG  D OP1   1 
ATOM   5796 O  OP2   . DG  D 3 24  ? 66.528  102.456 84.274  1.00 14.56 ? -11 DG  D OP2   1 
ATOM   5797 O  "O5'" . DG  D 3 24  ? 67.747  100.378 83.712  1.00 14.56 ? -11 DG  D "O5'" 1 
ATOM   5798 C  "C5'" . DG  D 3 24  ? 68.306  99.639  82.640  1.00 14.56 ? -11 DG  D "C5'" 1 
ATOM   5799 C  "C4'" . DG  D 3 24  ? 69.829  99.602  82.601  1.00 14.56 ? -11 DG  D "C4'" 1 
ATOM   5800 O  "O4'" . DG  D 3 24  ? 70.396  99.643  83.922  1.00 14.56 ? -11 DG  D "O4'" 1 
ATOM   5801 C  "C3'" . DG  D 3 24  ? 70.335  98.333  81.923  1.00 14.56 ? -11 DG  D "C3'" 1 
ATOM   5802 O  "O3'" . DG  D 3 24  ? 70.824  98.614  80.614  1.00 14.56 ? -11 DG  D "O3'" 1 
ATOM   5803 C  "C2'" . DG  D 3 24  ? 71.427  97.798  82.852  1.00 14.56 ? -11 DG  D "C2'" 1 
ATOM   5804 C  "C1'" . DG  D 3 24  ? 71.129  98.475  84.184  1.00 14.56 ? -11 DG  D "C1'" 1 
ATOM   5805 N  N9    . DG  D 3 24  ? 70.411  97.652  85.152  1.00 14.56 ? -11 DG  D N9    1 
ATOM   5806 C  C8    . DG  D 3 24  ? 69.092  97.289  85.118  1.00 14.56 ? -11 DG  D C8    1 
ATOM   5807 N  N7    . DG  D 3 24  ? 68.735  96.545  86.126  1.00 14.56 ? -11 DG  D N7    1 
ATOM   5808 C  C5    . DG  D 3 24  ? 69.896  96.401  86.869  1.00 14.56 ? -11 DG  D C5    1 
ATOM   5809 C  C6    . DG  D 3 24  ? 70.128  95.692  88.072  1.00 14.56 ? -11 DG  D C6    1 
ATOM   5810 O  O6    . DG  D 3 24  ? 69.326  95.032  88.742  1.00 14.56 ? -11 DG  D O6    1 
ATOM   5811 N  N1    . DG  D 3 24  ? 71.450  95.801  88.487  1.00 14.56 ? -11 DG  D N1    1 
ATOM   5812 C  C2    . DG  D 3 24  ? 72.422  96.506  87.825  1.00 14.56 ? -11 DG  D C2    1 
ATOM   5813 N  N2    . DG  D 3 24  ? 73.643  96.499  88.380  1.00 14.56 ? -11 DG  D N2    1 
ATOM   5814 N  N3    . DG  D 3 24  ? 72.215  97.173  86.698  1.00 14.56 ? -11 DG  D N3    1 
ATOM   5815 C  C4    . DG  D 3 24  ? 70.934  97.075  86.281  1.00 14.56 ? -11 DG  D C4    1 
ATOM   5816 P  P     . DC  D 3 25  ? 70.700  97.508  79.449  1.00 21.33 ? -10 DC  D P     1 
ATOM   5817 O  OP1   . DC  D 3 25  ? 71.000  98.186  78.178  1.00 21.33 ? -10 DC  D OP1   1 
ATOM   5818 O  OP2   . DC  D 3 25  ? 69.411  96.811  79.619  1.00 21.33 ? -10 DC  D OP2   1 
ATOM   5819 O  "O5'" . DC  D 3 25  ? 71.847  96.442  79.734  1.00 21.33 ? -10 DC  D "O5'" 1 
ATOM   5820 C  "C5'" . DC  D 3 25  ? 73.199  96.814  79.633  1.00 21.33 ? -10 DC  D "C5'" 1 
ATOM   5821 C  "C4'" . DC  D 3 25  ? 74.096  95.739  80.217  1.00 21.33 ? -10 DC  D "C4'" 1 
ATOM   5822 O  "O4'" . DC  D 3 25  ? 73.737  95.488  81.600  1.00 21.33 ? -10 DC  D "O4'" 1 
ATOM   5823 C  "C3'" . DC  D 3 25  ? 74.028  94.381  79.514  1.00 21.33 ? -10 DC  D "C3'" 1 
ATOM   5824 O  "O3'" . DC  D 3 25  ? 75.328  93.781  79.546  1.00 21.33 ? -10 DC  D "O3'" 1 
ATOM   5825 C  "C2'" . DC  D 3 25  ? 73.065  93.601  80.407  1.00 21.33 ? -10 DC  D "C2'" 1 
ATOM   5826 C  "C1'" . DC  D 3 25  ? 73.486  94.113  81.776  1.00 21.33 ? -10 DC  D "C1'" 1 
ATOM   5827 N  N1    . DC  D 3 25  ? 72.472  93.929  82.868  1.00 21.33 ? -10 DC  D N1    1 
ATOM   5828 C  C2    . DC  D 3 25  ? 72.843  94.171  84.199  1.00 21.33 ? -10 DC  D C2    1 
ATOM   5829 O  O2    . DC  D 3 25  ? 73.993  94.545  84.449  1.00 21.33 ? -10 DC  D O2    1 
ATOM   5830 N  N3    . DC  D 3 25  ? 71.928  93.993  85.177  1.00 21.33 ? -10 DC  D N3    1 
ATOM   5831 C  C4    . DC  D 3 25  ? 70.697  93.587  84.875  1.00 21.33 ? -10 DC  D C4    1 
ATOM   5832 N  N4    . DC  D 3 25  ? 69.831  93.429  85.878  1.00 21.33 ? -10 DC  D N4    1 
ATOM   5833 C  C5    . DC  D 3 25  ? 70.297  93.330  83.530  1.00 21.33 ? -10 DC  D C5    1 
ATOM   5834 C  C6    . DC  D 3 25  ? 71.210  93.507  82.566  1.00 21.33 ? -10 DC  D C6    1 
ATOM   5835 P  P     . DC  D 3 26  ? 75.842  92.731  78.436  1.00 35.59 ? -9  DC  D P     1 
ATOM   5836 O  OP1   . DC  D 3 26  ? 74.834  91.659  78.341  1.00 35.59 ? -9  DC  D OP1   1 
ATOM   5837 O  OP2   . DC  D 3 26  ? 77.241  92.424  78.798  1.00 35.59 ? -9  DC  D OP2   1 
ATOM   5838 O  "O5'" . DC  D 3 26  ? 75.882  93.506  77.026  1.00 35.59 ? -9  DC  D "O5'" 1 
ATOM   5839 C  "C5'" . DC  D 3 26  ? 76.627  94.721  76.892  1.00 35.59 ? -9  DC  D "C5'" 1 
ATOM   5840 C  "C4'" . DC  D 3 26  ? 77.156  94.897  75.473  1.00 35.59 ? -9  DC  D "C4'" 1 
ATOM   5841 O  "O4'" . DC  D 3 26  ? 77.520  96.290  75.256  1.00 35.59 ? -9  DC  D "O4'" 1 
ATOM   5842 C  "C3'" . DC  D 3 26  ? 78.426  94.105  75.169  1.00 35.59 ? -9  DC  D "C3'" 1 
ATOM   5843 O  "O3'" . DC  D 3 26  ? 78.505  93.808  73.768  1.00 35.59 ? -9  DC  D "O3'" 1 
ATOM   5844 C  "C2'" . DC  D 3 26  ? 79.517  95.078  75.606  1.00 35.59 ? -9  DC  D "C2'" 1 
ATOM   5845 C  "C1'" . DC  D 3 26  ? 78.931  96.397  75.115  1.00 35.59 ? -9  DC  D "C1'" 1 
ATOM   5846 N  N1    . DC  D 3 26  ? 79.394  97.618  75.862  1.00 35.59 ? -9  DC  D N1    1 
ATOM   5847 C  C2    . DC  D 3 26  ? 80.072  98.636  75.179  1.00 35.59 ? -9  DC  D C2    1 
ATOM   5848 O  O2    . DC  D 3 26  ? 80.344  98.485  73.986  1.00 35.59 ? -9  DC  D O2    1 
ATOM   5849 N  N3    . DC  D 3 26  ? 80.458  99.739  75.856  1.00 35.59 ? -9  DC  D N3    1 
ATOM   5850 C  C4    . DC  D 3 26  ? 80.151  99.869  77.143  1.00 35.59 ? -9  DC  D C4    1 
ATOM   5851 N  N4    . DC  D 3 26  ? 80.547  100.979 77.765  1.00 35.59 ? -9  DC  D N4    1 
ATOM   5852 C  C5    . DC  D 3 26  ? 79.434  98.862  77.850  1.00 35.59 ? -9  DC  D C5    1 
ATOM   5853 C  C6    . DC  D 3 26  ? 79.069  97.768  77.172  1.00 35.59 ? -9  DC  D C6    1 
ATOM   5854 P  P     . DT  D 3 27  ? 79.702  92.903  73.180  1.00 38.46 ? -8  DT  D P     1 
ATOM   5855 O  OP1   . DT  D 3 27  ? 79.250  92.335  71.894  1.00 38.46 ? -8  DT  D OP1   1 
ATOM   5856 O  OP2   . DT  D 3 27  ? 80.121  92.006  74.277  1.00 38.46 ? -8  DT  D OP2   1 
ATOM   5857 O  "O5'" . DT  D 3 27  ? 80.894  93.930  72.854  1.00 38.46 ? -8  DT  D "O5'" 1 
ATOM   5858 C  "C5'" . DT  D 3 27  ? 82.244  93.593  73.196  1.00 38.46 ? -8  DT  D "C5'" 1 
ATOM   5859 C  "C4'" . DT  D 3 27  ? 83.206  94.753  72.953  1.00 38.46 ? -8  DT  D "C4'" 1 
ATOM   5860 O  "O4'" . DT  D 3 27  ? 82.857  95.884  73.796  1.00 38.46 ? -8  DT  D "O4'" 1 
ATOM   5861 C  "C3'" . DT  D 3 27  ? 84.641  94.374  73.334  1.00 38.46 ? -8  DT  D "C3'" 1 
ATOM   5862 O  "O3'" . DT  D 3 27  ? 85.643  94.634  72.290  1.00 38.46 ? -8  DT  D "O3'" 1 
ATOM   5863 C  "C2'" . DT  D 3 27  ? 84.880  95.082  74.664  1.00 38.46 ? -8  DT  D "C2'" 1 
ATOM   5864 C  "C1'" . DT  D 3 27  ? 83.991  96.300  74.529  1.00 38.46 ? -8  DT  D "C1'" 1 
ATOM   5865 N  N1    . DT  D 3 27  ? 83.555  96.844  75.828  1.00 38.46 ? -8  DT  D N1    1 
ATOM   5866 C  C2    . DT  D 3 27  ? 83.943  98.112  76.185  1.00 38.46 ? -8  DT  D C2    1 
ATOM   5867 O  O2    . DT  D 3 27  ? 84.618  98.833  75.471  1.00 38.46 ? -8  DT  D O2    1 
ATOM   5868 N  N3    . DT  D 3 27  ? 83.497  98.522  77.407  1.00 38.46 ? -8  DT  D N3    1 
ATOM   5869 C  C4    . DT  D 3 27  ? 82.727  97.806  78.293  1.00 38.46 ? -8  DT  D C4    1 
ATOM   5870 O  O4    . DT  D 3 27  ? 82.381  98.269  79.373  1.00 38.46 ? -8  DT  D O4    1 
ATOM   5871 C  C5    . DT  D 3 27  ? 82.366  96.475  77.860  1.00 38.46 ? -8  DT  D C5    1 
ATOM   5872 C  C7    . DT  D 3 27  ? 81.534  95.591  78.737  1.00 38.46 ? -8  DT  D C7    1 
ATOM   5873 C  C6    . DT  D 3 27  ? 82.796  96.066  76.663  1.00 38.46 ? -8  DT  D C6    1 
ATOM   5874 P  P     . DT  D 3 28  ? 86.100  96.101  71.796  1.00 42.39 ? -7  DT  D P     1 
ATOM   5875 O  OP1   . DT  D 3 28  ? 84.938  96.876  71.291  1.00 42.39 ? -7  DT  D OP1   1 
ATOM   5876 O  OP2   . DT  D 3 28  ? 87.249  95.871  70.894  1.00 42.39 ? -7  DT  D OP2   1 
ATOM   5877 O  "O5'" . DT  D 3 28  ? 86.674  96.796  73.122  1.00 42.39 ? -7  DT  D "O5'" 1 
ATOM   5878 C  "C5'" . DT  D 3 28  ? 87.734  97.729  73.041  1.00 42.39 ? -7  DT  D "C5'" 1 
ATOM   5879 C  "C4'" . DT  D 3 28  ? 88.483  97.801  74.366  1.00 42.39 ? -7  DT  D "C4'" 1 
ATOM   5880 O  "O4'" . DT  D 3 28  ? 87.651  98.240  75.457  1.00 42.39 ? -7  DT  D "O4'" 1 
ATOM   5881 C  "C3'" . DT  D 3 28  ? 88.950  96.458  74.830  1.00 42.39 ? -7  DT  D "C3'" 1 
ATOM   5882 O  "O3'" . DT  D 3 28  ? 90.062  96.011  74.098  1.00 42.39 ? -7  DT  D "O3'" 1 
ATOM   5883 C  "C2'" . DT  D 3 28  ? 89.273  96.729  76.309  1.00 42.39 ? -7  DT  D "C2'" 1 
ATOM   5884 C  "C1'" . DT  D 3 28  ? 88.281  97.847  76.680  1.00 42.39 ? -7  DT  D "C1'" 1 
ATOM   5885 N  N1    . DT  D 3 28  ? 87.248  97.391  77.662  1.00 42.39 ? -7  DT  D N1    1 
ATOM   5886 C  C2    . DT  D 3 28  ? 86.877  98.235  78.679  1.00 42.39 ? -7  DT  D C2    1 
ATOM   5887 O  O2    . DT  D 3 28  ? 87.217  99.402  78.733  1.00 42.39 ? -7  DT  D O2    1 
ATOM   5888 N  N3    . DT  D 3 28  ? 85.959  97.719  79.544  1.00 42.39 ? -7  DT  D N3    1 
ATOM   5889 C  C4    . DT  D 3 28  ? 85.468  96.436  79.566  1.00 42.39 ? -7  DT  D C4    1 
ATOM   5890 O  O4    . DT  D 3 28  ? 84.659  96.061  80.405  1.00 42.39 ? -7  DT  D O4    1 
ATOM   5891 C  C5    . DT  D 3 28  ? 85.965  95.568  78.527  1.00 42.39 ? -7  DT  D C5    1 
ATOM   5892 C  C7    . DT  D 3 28  ? 85.505  94.142  78.450  1.00 42.39 ? -7  DT  D C7    1 
ATOM   5893 C  C6    . DT  D 3 28  ? 86.844  96.072  77.653  1.00 42.39 ? -7  DT  D C6    1 
ATOM   5894 P  P     . DA  D 3 29  ? 90.613  94.528  74.380  1.00 48.34 ? -6  DA  D P     1 
ATOM   5895 O  OP1   . DA  D 3 29  ? 91.521  94.144  73.271  1.00 48.34 ? -6  DA  D OP1   1 
ATOM   5896 O  OP2   . DA  D 3 29  ? 89.476  93.656  74.747  1.00 48.34 ? -6  DA  D OP2   1 
ATOM   5897 O  "O5'" . DA  D 3 29  ? 91.481  94.728  75.684  1.00 48.34 ? -6  DA  D "O5'" 1 
ATOM   5898 C  "C5'" . DA  D 3 29  ? 91.668  93.684  76.578  1.00 48.34 ? -6  DA  D "C5'" 1 
ATOM   5899 C  "C4'" . DA  D 3 29  ? 91.842  94.264  77.950  1.00 48.34 ? -6  DA  D "C4'" 1 
ATOM   5900 O  "O4'" . DA  D 3 29  ? 90.566  94.831  78.441  1.00 48.34 ? -6  DA  D "O4'" 1 
ATOM   5901 C  "C3'" . DA  D 3 29  ? 92.274  93.248  79.026  1.00 48.34 ? -6  DA  D "C3'" 1 
ATOM   5902 O  "O3'" . DA  D 3 29  ? 93.369  93.816  79.781  1.00 48.34 ? -6  DA  D "O3'" 1 
ATOM   5903 C  "C2'" . DA  D 3 29  ? 90.994  93.093  79.834  1.00 48.34 ? -6  DA  D "C2'" 1 
ATOM   5904 C  "C1'" . DA  D 3 29  ? 90.539  94.522  79.798  1.00 48.34 ? -6  DA  D "C1'" 1 
ATOM   5905 N  N9    . DA  D 3 29  ? 89.286  94.833  80.483  1.00 48.34 ? -6  DA  D N9    1 
ATOM   5906 C  C8    . DA  D 3 29  ? 88.953  96.057  80.989  1.00 48.34 ? -6  DA  D C8    1 
ATOM   5907 N  N7    . DA  D 3 29  ? 87.843  96.069  81.672  1.00 48.34 ? -6  DA  D N7    1 
ATOM   5908 C  C5    . DA  D 3 29  ? 87.466  94.744  81.722  1.00 48.34 ? -6  DA  D C5    1 
ATOM   5909 C  C6    . DA  D 3 29  ? 86.374  94.098  82.321  1.00 48.34 ? -6  DA  D C6    1 
ATOM   5910 N  N6    . DA  D 3 29  ? 85.428  94.738  83.005  1.00 48.34 ? -6  DA  D N6    1 
ATOM   5911 N  N1    . DA  D 3 29  ? 86.285  92.756  82.188  1.00 48.34 ? -6  DA  D N1    1 
ATOM   5912 C  C2    . DA  D 3 29  ? 87.227  92.114  81.498  1.00 48.34 ? -6  DA  D C2    1 
ATOM   5913 N  N3    . DA  D 3 29  ? 88.299  92.611  80.888  1.00 48.34 ? -6  DA  D N3    1 
ATOM   5914 C  C4    . DA  D 3 29  ? 88.364  93.950  81.033  1.00 48.34 ? -6  DA  D C4    1 
ATOM   5915 P  P     . DG  D 3 30  ? 93.524  93.564  81.366  1.00 38.74 ? -5  DG  D P     1 
ATOM   5916 O  OP1   . DG  D 3 30  ? 94.866  94.043  81.759  1.00 38.74 ? -5  DG  D OP1   1 
ATOM   5917 O  OP2   . DG  D 3 30  ? 93.196  92.151  81.664  1.00 38.74 ? -5  DG  D OP2   1 
ATOM   5918 O  "O5'" . DG  D 3 30  ? 92.399  94.515  82.030  1.00 38.74 ? -5  DG  D "O5'" 1 
ATOM   5919 C  "C5'" . DG  D 3 30  ? 92.610  95.918  82.331  1.00 38.74 ? -5  DG  D "C5'" 1 
ATOM   5920 C  "C4'" . DG  D 3 30  ? 93.281  96.735  81.227  1.00 38.74 ? -5  DG  D "C4'" 1 
ATOM   5921 O  "O4'" . DG  D 3 30  ? 92.535  96.782  79.966  1.00 38.74 ? -5  DG  D "O4'" 1 
ATOM   5922 C  "C3'" . DG  D 3 30  ? 93.479  98.221  81.614  1.00 38.74 ? -5  DG  D "C3'" 1 
ATOM   5923 O  "O3'" . DG  D 3 30  ? 94.844  98.573  81.544  1.00 38.74 ? -5  DG  D "O3'" 1 
ATOM   5924 C  "C2'" . DG  D 3 30  ? 92.691  98.978  80.549  1.00 38.74 ? -5  DG  D "C2'" 1 
ATOM   5925 C  "C1'" . DG  D 3 30  ? 92.914  98.022  79.430  1.00 38.74 ? -5  DG  D "C1'" 1 
ATOM   5926 N  N9    . DG  D 3 30  ? 92.334  98.409  78.151  1.00 38.74 ? -5  DG  D N9    1 
ATOM   5927 C  C8    . DG  D 3 30  ? 91.431  99.414  77.945  1.00 38.74 ? -5  DG  D C8    1 
ATOM   5928 N  N7    . DG  D 3 30  ? 91.184  99.638  76.692  1.00 38.74 ? -5  DG  D N7    1 
ATOM   5929 C  C5    . DG  D 3 30  ? 92.042  98.786  76.014  1.00 38.74 ? -5  DG  D C5    1 
ATOM   5930 C  C6    . DG  D 3 30  ? 92.228  98.602  74.628  1.00 38.74 ? -5  DG  D C6    1 
ATOM   5931 O  O6    . DG  D 3 30  ? 91.650  99.174  73.695  1.00 38.74 ? -5  DG  D O6    1 
ATOM   5932 N  N1    . DG  D 3 30  ? 93.187  97.642  74.359  1.00 38.74 ? -5  DG  D N1    1 
ATOM   5933 C  C2    . DG  D 3 30  ? 93.887  96.951  75.310  1.00 38.74 ? -5  DG  D C2    1 
ATOM   5934 N  N2    . DG  D 3 30  ? 94.783  96.060  74.856  1.00 38.74 ? -5  DG  D N2    1 
ATOM   5935 N  N3    . DG  D 3 30  ? 93.724  97.118  76.616  1.00 38.74 ? -5  DG  D N3    1 
ATOM   5936 C  C4    . DG  D 3 30  ? 92.787  98.054  76.892  1.00 38.74 ? -5  DG  D C4    1 
ATOM   5937 P  P     . DG  D 3 31  ? 95.341  99.964  82.168  1.00 2.37  ? -4  DG  D P     1 
ATOM   5938 O  OP1   . DG  D 3 31  ? 96.767  99.835  82.517  1.00 2.37  ? -4  DG  D OP1   1 
ATOM   5939 O  OP2   . DG  D 3 31  ? 94.371  100.340 83.213  1.00 2.37  ? -4  DG  D OP2   1 
ATOM   5940 O  "O5'" . DG  D 3 31  ? 95.164  101.014 80.978  1.00 2.37  ? -4  DG  D "O5'" 1 
ATOM   5941 C  "C5'" . DG  D 3 31  ? 95.942  100.947 79.820  1.00 2.37  ? -4  DG  D "C5'" 1 
ATOM   5942 C  "C4'" . DG  D 3 31  ? 96.841  102.160 79.664  1.00 2.37  ? -4  DG  D "C4'" 1 
ATOM   5943 O  "O4'" . DG  D 3 31  ? 96.281  103.326 80.291  1.00 2.37  ? -4  DG  D "O4'" 1 
ATOM   5944 C  "C3'" . DG  D 3 31  ? 98.217  102.015 80.249  1.00 2.37  ? -4  DG  D "C3'" 1 
ATOM   5945 O  "O3'" . DG  D 3 31  ? 99.006  101.387 79.276  1.00 2.37  ? -4  DG  D "O3'" 1 
ATOM   5946 C  "C2'" . DG  D 3 31  ? 98.636  103.467 80.459  1.00 2.37  ? -4  DG  D "C2'" 1 
ATOM   5947 C  "C1'" . DG  D 3 31  ? 97.322  104.156 80.777  1.00 2.37  ? -4  DG  D "C1'" 1 
ATOM   5948 N  N9    . DG  D 3 31  ? 97.088  104.442 82.181  1.00 2.37  ? -4  DG  D N9    1 
ATOM   5949 C  C8    . DG  D 3 31  ? 96.410  103.672 83.080  1.00 2.37  ? -4  DG  D C8    1 
ATOM   5950 N  N7    . DG  D 3 31  ? 96.287  104.223 84.243  1.00 2.37  ? -4  DG  D N7    1 
ATOM   5951 C  C5    . DG  D 3 31  ? 96.865  105.462 84.093  1.00 2.37  ? -4  DG  D C5    1 
ATOM   5952 C  C6    . DG  D 3 31  ? 97.016  106.509 85.018  1.00 2.37  ? -4  DG  D C6    1 
ATOM   5953 O  O6    . DG  D 3 31  ? 96.644  106.552 86.187  1.00 2.37  ? -4  DG  D O6    1 
ATOM   5954 N  N1    . DG  D 3 31  ? 97.666  107.608 84.459  1.00 2.37  ? -4  DG  D N1    1 
ATOM   5955 C  C2    . DG  D 3 31  ? 98.117  107.665 83.172  1.00 2.37  ? -4  DG  D C2    1 
ATOM   5956 N  N2    . DG  D 3 31  ? 98.716  108.802 82.811  1.00 2.37  ? -4  DG  D N2    1 
ATOM   5957 N  N3    . DG  D 3 31  ? 97.981  106.685 82.296  1.00 2.37  ? -4  DG  D N3    1 
ATOM   5958 C  C4    . DG  D 3 31  ? 97.349  105.620 82.825  1.00 2.37  ? -4  DG  D C4    1 
ATOM   5959 P  P     . DG  D 3 32  ? 100.448 100.784 79.592  1.00 2.37  ? -3  DG  D P     1 
ATOM   5960 O  OP1   . DG  D 3 32  ? 100.840 100.022 78.400  1.00 2.37  ? -3  DG  D OP1   1 
ATOM   5961 O  OP2   . DG  D 3 32  ? 100.428 100.119 80.901  1.00 2.37  ? -3  DG  D OP2   1 
ATOM   5962 O  "O5'" . DG  D 3 32  ? 101.364 102.070 79.667  1.00 2.37  ? -3  DG  D "O5'" 1 
ATOM   5963 C  "C5'" . DG  D 3 32  ? 101.499 102.900 78.536  1.00 2.37  ? -3  DG  D "C5'" 1 
ATOM   5964 C  "C4'" . DG  D 3 32  ? 102.345 104.097 78.872  1.00 2.37  ? -3  DG  D "C4'" 1 
ATOM   5965 O  "O4'" . DG  D 3 32  ? 101.722 104.872 79.922  1.00 2.37  ? -3  DG  D "O4'" 1 
ATOM   5966 C  "C3'" . DG  D 3 32  ? 103.735 103.709 79.365  1.00 2.37  ? -3  DG  D "C3'" 1 
ATOM   5967 O  "O3'" . DG  D 3 32  ? 104.731 104.513 78.748  1.00 2.37  ? -3  DG  D "O3'" 1 
ATOM   5968 C  "C2'" . DG  D 3 32  ? 103.664 103.907 80.871  1.00 2.37  ? -3  DG  D "C2'" 1 
ATOM   5969 C  "C1'" . DG  D 3 32  ? 102.570 104.949 81.040  1.00 2.37  ? -3  DG  D "C1'" 1 
ATOM   5970 N  N9    . DG  D 3 32  ? 101.791 104.773 82.262  1.00 2.37  ? -3  DG  D N9    1 
ATOM   5971 C  C8    . DG  D 3 32  ? 101.294 103.598 82.768  1.00 2.37  ? -3  DG  D C8    1 
ATOM   5972 N  N7    . DG  D 3 32  ? 100.694 103.739 83.912  1.00 2.37  ? -3  DG  D N7    1 
ATOM   5973 C  C5    . DG  D 3 32  ? 100.862 105.079 84.211  1.00 2.37  ? -3  DG  D C5    1 
ATOM   5974 C  C6    . DG  D 3 32  ? 100.447 105.816 85.330  1.00 2.37  ? -3  DG  D C6    1 
ATOM   5975 O  O6    . DG  D 3 32  ? 99.820  105.422 86.308  1.00 2.37  ? -3  DG  D O6    1 
ATOM   5976 N  N1    . DG  D 3 32  ? 100.818 107.155 85.236  1.00 2.37  ? -3  DG  D N1    1 
ATOM   5977 C  C2    . DG  D 3 32  ? 101.507 107.693 84.191  1.00 2.37  ? -3  DG  D C2    1 
ATOM   5978 N  N2    . DG  D 3 32  ? 101.791 108.998 84.269  1.00 2.37  ? -3  DG  D N2    1 
ATOM   5979 N  N3    . DG  D 3 32  ? 101.903 107.011 83.141  1.00 2.37  ? -3  DG  D N3    1 
ATOM   5980 C  C4    . DG  D 3 32  ? 101.546 105.719 83.215  1.00 2.37  ? -3  DG  D C4    1 
ATOM   5981 P  P     . DG  D 3 33  ? 106.289 104.218 78.994  1.00 2.91  ? -2  DG  D P     1 
ATOM   5982 O  OP1   . DG  D 3 33  ? 107.003 104.750 77.821  1.00 2.91  ? -2  DG  D OP1   1 
ATOM   5983 O  OP2   . DG  D 3 33  ? 106.425 102.789 79.322  1.00 2.91  ? -2  DG  D OP2   1 
ATOM   5984 O  "O5'" . DG  D 3 33  ? 106.678 105.039 80.313  1.00 2.91  ? -2  DG  D "O5'" 1 
ATOM   5985 C  "C5'" . DG  D 3 33  ? 106.647 106.449 80.313  1.00 2.91  ? -2  DG  D "C5'" 1 
ATOM   5986 C  "C4'" . DG  D 3 33  ? 106.629 106.998 81.730  1.00 2.91  ? -2  DG  D "C4'" 1 
ATOM   5987 O  "O4'" . DG  D 3 33  ? 105.473 106.557 82.443  1.00 2.91  ? -2  DG  D "O4'" 1 
ATOM   5988 C  "C3'" . DG  D 3 33  ? 107.777 106.561 82.623  1.00 2.91  ? -2  DG  D "C3'" 1 
ATOM   5989 O  "O3'" . DG  D 3 33  ? 108.912 107.405 82.443  1.00 2.91  ? -2  DG  D "O3'" 1 
ATOM   5990 C  "C2'" . DG  D 3 33  ? 107.195 106.699 84.030  1.00 2.91  ? -2  DG  D "C2'" 1 
ATOM   5991 C  "C1'" . DG  D 3 33  ? 105.704 106.878 83.787  1.00 2.91  ? -2  DG  D "C1'" 1 
ATOM   5992 N  N9    . DG  D 3 33  ? 104.872 106.060 84.653  1.00 2.91  ? -2  DG  D N9    1 
ATOM   5993 C  C8    . DG  D 3 33  ? 104.561 104.741 84.498  1.00 2.91  ? -2  DG  D C8    1 
ATOM   5994 N  N7    . DG  D 3 33  ? 103.845 104.265 85.471  1.00 2.91  ? -2  DG  D N7    1 
ATOM   5995 C  C5    . DG  D 3 33  ? 103.709 105.333 86.344  1.00 2.91  ? -2  DG  D C5    1 
ATOM   5996 C  C6    . DG  D 3 33  ? 103.048 105.419 87.583  1.00 2.91  ? -2  DG  D C6    1 
ATOM   5997 O  O6    . DG  D 3 33  ? 102.406 104.553 88.173  1.00 2.91  ? -2  DG  D O6    1 
ATOM   5998 N  N1    . DG  D 3 33  ? 103.171 106.680 88.143  1.00 2.91  ? -2  DG  D N1    1 
ATOM   5999 C  C2    . DG  D 3 33  ? 103.834 107.717 87.576  1.00 2.91  ? -2  DG  D C2    1 
ATOM   6000 N  N2    . DG  D 3 33  ? 103.837 108.849 88.262  1.00 2.91  ? -2  DG  D N2    1 
ATOM   6001 N  N3    . DG  D 3 33  ? 104.455 107.653 86.421  1.00 2.91  ? -2  DG  D N3    1 
ATOM   6002 C  C4    . DG  D 3 33  ? 104.357 106.430 85.865  1.00 2.91  ? -2  DG  D C4    1 
ATOM   6003 P  P     . DC  D 3 34  ? 110.271 107.132 83.259  1.00 2.37  ? -1  DC  D P     1 
ATOM   6004 O  OP1   . DC  D 3 34  ? 111.396 107.729 82.517  1.00 2.37  ? -1  DC  D OP1   1 
ATOM   6005 O  OP2   . DC  D 3 34  ? 110.303 105.696 83.571  1.00 2.37  ? -1  DC  D OP2   1 
ATOM   6006 O  "O5'" . DC  D 3 34  ? 110.087 107.890 84.657  1.00 2.37  ? -1  DC  D "O5'" 1 
ATOM   6007 C  "C5'" . DC  D 3 34  ? 109.805 109.281 84.699  1.00 2.37  ? -1  DC  D "C5'" 1 
ATOM   6008 C  "C4'" . DC  D 3 34  ? 109.607 109.763 86.136  1.00 2.37  ? -1  DC  D "C4'" 1 
ATOM   6009 O  "O4'" . DC  D 3 34  ? 108.443 109.123 86.735  1.00 2.37  ? -1  DC  D "O4'" 1 
ATOM   6010 C  "C3'" . DC  D 3 34  ? 110.776 109.454 87.058  1.00 2.37  ? -1  DC  D "C3'" 1 
ATOM   6011 O  "O3'" . DC  D 3 34  ? 111.012 110.538 87.912  1.00 2.37  ? -1  DC  D "O3'" 1 
ATOM   6012 C  "C2'" . DC  D 3 34  ? 110.295 108.246 87.858  1.00 2.37  ? -1  DC  D "C2'" 1 
ATOM   6013 C  "C1'" . DC  D 3 34  ? 108.803 108.494 87.950  1.00 2.37  ? -1  DC  D "C1'" 1 
ATOM   6014 N  N1    . DC  D 3 34  ? 107.972 107.247 88.150  1.00 2.37  ? -1  DC  D N1    1 
ATOM   6015 C  C2    . DC  D 3 34  ? 107.193 107.090 89.307  1.00 2.37  ? -1  DC  D C2    1 
ATOM   6016 O  O2    . DC  D 3 34  ? 107.198 107.974 90.166  1.00 2.37  ? -1  DC  D O2    1 
ATOM   6017 N  N3    . DC  D 3 34  ? 106.453 105.963 89.459  1.00 2.37  ? -1  DC  D N3    1 
ATOM   6018 C  C4    . DC  D 3 34  ? 106.475 105.029 88.522  1.00 2.37  ? -1  DC  D C4    1 
ATOM   6019 N  N4    . DC  D 3 34  ? 105.733 103.929 88.709  1.00 2.37  ? -1  DC  D N4    1 
ATOM   6020 C  C5    . DC  D 3 34  ? 107.257 105.174 87.343  1.00 2.37  ? -1  DC  D C5    1 
ATOM   6021 C  C6    . DC  D 3 34  ? 107.979 106.285 87.206  1.00 2.37  ? -1  DC  D C6    1 
ATOM   6022 P  P     . DT  E 4 1   ? 113.543 105.929 88.416  1.00 -0.00 ? 1   DT  F P     1 
ATOM   6023 O  OP1   . DT  E 4 1   ? 114.590 106.949 88.209  1.00 -0.00 ? 1   DT  F OP1   1 
ATOM   6024 O  OP2   . DT  E 4 1   ? 113.876 104.653 89.083  1.00 -0.00 ? 1   DT  F OP2   1 
ATOM   6025 O  "O5'" . DT  E 4 1   ? 112.398 106.644 89.257  1.00 -0.00 ? 1   DT  F "O5'" 1 
ATOM   6026 C  "C5'" . DT  E 4 1   ? 112.734 107.495 90.324  1.00 -0.00 ? 1   DT  F "C5'" 1 
ATOM   6027 C  "C4'" . DT  E 4 1   ? 111.910 107.163 91.544  1.00 -0.00 ? 1   DT  F "C4'" 1 
ATOM   6028 O  "O4'" . DT  E 4 1   ? 110.573 106.772 91.151  1.00 -0.00 ? 1   DT  F "O4'" 1 
ATOM   6029 C  "C3'" . DT  E 4 1   ? 112.407 105.978 92.308  1.00 -0.00 ? 1   DT  F "C3'" 1 
ATOM   6030 O  "O3'" . DT  E 4 1   ? 113.466 106.320 93.170  1.00 -0.00 ? 1   DT  F "O3'" 1 
ATOM   6031 C  "C2'" . DT  E 4 1   ? 111.166 105.585 93.102  1.00 -0.00 ? 1   DT  F "C2'" 1 
ATOM   6032 C  "C1'" . DT  E 4 1   ? 110.022 105.979 92.182  1.00 -0.00 ? 1   DT  F "C1'" 1 
ATOM   6033 N  N1    . DT  E 4 1   ? 109.315 104.806 91.620  1.00 -0.00 ? 1   DT  F N1    1 
ATOM   6034 C  C2    . DT  E 4 1   ? 108.329 104.204 92.369  1.00 -0.00 ? 1   DT  F C2    1 
ATOM   6035 O  O2    . DT  E 4 1   ? 108.010 104.577 93.476  1.00 -0.00 ? 1   DT  F O2    1 
ATOM   6036 N  N3    . DT  E 4 1   ? 107.743 103.128 91.787  1.00 -0.00 ? 1   DT  F N3    1 
ATOM   6037 C  C4    . DT  E 4 1   ? 108.032 102.601 90.551  1.00 -0.00 ? 1   DT  F C4    1 
ATOM   6038 O  O4    . DT  E 4 1   ? 107.439 101.629 90.108  1.00 -0.00 ? 1   DT  F O4    1 
ATOM   6039 C  C5    . DT  E 4 1   ? 109.073 103.281 89.815  1.00 -0.00 ? 1   DT  F C5    1 
ATOM   6040 C  C7    . DT  E 4 1   ? 109.470 102.806 88.458  1.00 -0.00 ? 1   DT  F C7    1 
ATOM   6041 C  C6    . DT  E 4 1   ? 109.652 104.339 90.380  1.00 -0.00 ? 1   DT  F C6    1 
ATOM   6042 P  P     . DT  E 4 2   ? 114.248 105.126 93.901  1.00 2.37  ? 2   DT  F P     1 
ATOM   6043 O  OP1   . DT  E 4 2   ? 115.306 105.764 94.691  1.00 2.37  ? 2   DT  F OP1   1 
ATOM   6044 O  OP2   . DT  E 4 2   ? 114.570 104.053 92.951  1.00 2.37  ? 2   DT  F OP2   1 
ATOM   6045 O  "O5'" . DT  E 4 2   ? 113.168 104.553 94.904  1.00 2.37  ? 2   DT  F "O5'" 1 
ATOM   6046 C  "C5'" . DT  E 4 2   ? 113.115 103.192 95.180  1.00 2.37  ? 2   DT  F "C5'" 1 
ATOM   6047 C  "C4'" . DT  E 4 2   ? 111.892 102.903 96.008  1.00 2.37  ? 2   DT  F "C4'" 1 
ATOM   6048 O  "O4'" . DT  E 4 2   ? 110.722 102.906 95.159  1.00 2.37  ? 2   DT  F "O4'" 1 
ATOM   6049 C  "C3'" . DT  E 4 2   ? 111.906 101.563 96.683  1.00 2.37  ? 2   DT  F "C3'" 1 
ATOM   6050 O  "O3'" . DT  E 4 2   ? 112.443 101.676 97.937  1.00 2.37  ? 2   DT  F "O3'" 1 
ATOM   6051 C  "C2'" . DT  E 4 2   ? 110.433 101.213 96.780  1.00 2.37  ? 2   DT  F "C2'" 1 
ATOM   6052 C  "C1'" . DT  E 4 2   ? 109.811 101.932 95.594  1.00 2.37  ? 2   DT  F "C1'" 1 
ATOM   6053 N  N1    . DT  E 4 2   ? 109.481 101.039 94.469  1.00 2.37  ? 2   DT  F N1    1 
ATOM   6054 C  C2    . DT  E 4 2   ? 108.443 100.155 94.606  1.00 2.37  ? 2   DT  F C2    1 
ATOM   6055 O  O2    . DT  E 4 2   ? 107.787 100.049 95.615  1.00 2.37  ? 2   DT  F O2    1 
ATOM   6056 N  N3    . DT  E 4 2   ? 108.214 99.374  93.526  1.00 2.37  ? 2   DT  F N3    1 
ATOM   6057 C  C4    . DT  E 4 2   ? 108.879 99.398  92.334  1.00 2.37  ? 2   DT  F C4    1 
ATOM   6058 O  O4    . DT  E 4 2   ? 108.583 98.653  91.416  1.00 2.37  ? 2   DT  F O4    1 
ATOM   6059 C  C5    . DT  E 4 2   ? 109.953 100.356 92.239  1.00 2.37  ? 2   DT  F C5    1 
ATOM   6060 C  C7    . DT  E 4 2   ? 110.761 100.455 90.981  1.00 2.37  ? 2   DT  F C7    1 
ATOM   6061 C  C6    . DT  E 4 2   ? 110.197 101.129 93.300  1.00 2.37  ? 2   DT  F C6    1 
ATOM   6062 P  P     . DG  E 4 3   ? 113.257 100.447 98.537  1.00 2.37  ? 3   DG  F P     1 
ATOM   6063 O  OP1   . DG  E 4 3   ? 114.029 100.959 99.684  1.00 2.37  ? 3   DG  F OP1   1 
ATOM   6064 O  OP2   . DG  E 4 3   ? 113.927 99.745  97.424  1.00 2.37  ? 3   DG  F OP2   1 
ATOM   6065 O  "O5'" . DG  E 4 3   ? 112.091 99.496  99.042  1.00 2.37  ? 3   DG  F "O5'" 1 
ATOM   6066 C  "C5'" . DG  E 4 3   ? 111.181 99.946  100.023 1.00 2.37  ? 3   DG  F "C5'" 1 
ATOM   6067 C  "C4'" . DG  E 4 3   ? 110.210 98.844  100.369 1.00 2.37  ? 3   DG  F "C4'" 1 
ATOM   6068 O  "O4'" . DG  E 4 3   ? 109.321 98.598  99.244  1.00 2.37  ? 3   DG  F "O4'" 1 
ATOM   6069 C  "C3'" . DG  E 4 3   ? 110.925 97.538  100.664 1.00 2.37  ? 3   DG  F "C3'" 1 
ATOM   6070 O  "O3'" . DG  E 4 3   ? 110.427 96.896  101.817 1.00 2.37  ? 3   DG  F "O3'" 1 
ATOM   6071 C  "C2'" . DG  E 4 3   ? 110.721 96.732  99.402  1.00 2.37  ? 3   DG  F "C2'" 1 
ATOM   6072 C  "C1'" . DG  E 4 3   ? 109.404 97.257  98.866  1.00 2.37  ? 3   DG  F "C1'" 1 
ATOM   6073 N  N9    . DG  E 4 3   ? 109.324 97.106  97.416  1.00 2.37  ? 3   DG  F N9    1 
ATOM   6074 C  C8    . DG  E 4 3   ? 110.173 97.640  96.487  1.00 2.37  ? 3   DG  F C8    1 
ATOM   6075 N  N7    . DG  E 4 3   ? 109.934 97.241  95.274  1.00 2.37  ? 3   DG  F N7    1 
ATOM   6076 C  C5    . DG  E 4 3   ? 108.904 96.327  95.417  1.00 2.37  ? 3   DG  F C5    1 
ATOM   6077 C  C6    . DG  E 4 3   ? 108.236 95.555  94.450  1.00 2.37  ? 3   DG  F C6    1 
ATOM   6078 O  O6    . DG  E 4 3   ? 108.414 95.530  93.234  1.00 2.37  ? 3   DG  F O6    1 
ATOM   6079 N  N1    . DG  E 4 3   ? 107.247 94.766  95.018  1.00 2.37  ? 3   DG  F N1    1 
ATOM   6080 C  C2    . DG  E 4 3   ? 106.952 94.728  96.344  1.00 2.37  ? 3   DG  F C2    1 
ATOM   6081 N  N2    . DG  E 4 3   ? 105.974 93.895  96.704  1.00 2.37  ? 3   DG  F N2    1 
ATOM   6082 N  N3    . DG  E 4 3   ? 107.574 95.442  97.261  1.00 2.37  ? 3   DG  F N3    1 
ATOM   6083 C  C4    . DG  E 4 3   ? 108.536 96.214  96.728  1.00 2.37  ? 3   DG  F C4    1 
ATOM   6084 P  P     . DC  E 4 4   ? 111.076 95.501  102.276 1.00 2.37  ? 4   DC  F P     1 
ATOM   6085 O  OP1   . DC  E 4 4   ? 110.919 95.329  103.731 1.00 2.37  ? 4   DC  F OP1   1 
ATOM   6086 O  OP2   . DC  E 4 4   ? 112.405 95.420  101.653 1.00 2.37  ? 4   DC  F OP2   1 
ATOM   6087 O  "O5'" . DC  E 4 4   ? 110.205 94.398  101.544 1.00 2.37  ? 4   DC  F "O5'" 1 
ATOM   6088 C  "C5'" . DC  E 4 4   ? 108.856 94.234  101.874 1.00 2.37  ? 4   DC  F "C5'" 1 
ATOM   6089 C  "C4'" . DC  E 4 4   ? 108.268 93.132  101.049 1.00 2.37  ? 4   DC  F "C4'" 1 
ATOM   6090 O  "O4'" . DC  E 4 4   ? 108.320 93.471  99.663  1.00 2.37  ? 4   DC  F "O4'" 1 
ATOM   6091 C  "C3'" . DC  E 4 4   ? 109.008 91.812  101.144 1.00 2.37  ? 4   DC  F "C3'" 1 
ATOM   6092 O  "O3'" . DC  E 4 4   ? 108.547 91.081  102.251 1.00 2.37  ? 4   DC  F "O3'" 1 
ATOM   6093 C  "C2'" . DC  E 4 4   ? 108.675 91.119  99.830  1.00 2.37  ? 4   DC  F "C2'" 1 
ATOM   6094 C  "C1'" . DC  E 4 4   ? 108.309 92.276  98.917  1.00 2.37  ? 4   DC  F "C1'" 1 
ATOM   6095 N  N1    . DC  E 4 4   ? 109.087 92.423  97.680  1.00 2.37  ? 4   DC  F N1    1 
ATOM   6096 C  C2    . DC  E 4 4   ? 108.715 91.675  96.574  1.00 2.37  ? 4   DC  F C2    1 
ATOM   6097 O  O2    . DC  E 4 4   ? 107.812 90.849  96.698  1.00 2.37  ? 4   DC  F O2    1 
ATOM   6098 N  N3    . DC  E 4 4   ? 109.367 91.846  95.421  1.00 2.37  ? 4   DC  F N3    1 
ATOM   6099 C  C4    . DC  E 4 4   ? 110.335 92.752  95.340  1.00 2.37  ? 4   DC  F C4    1 
ATOM   6100 N  N4    . DC  E 4 4   ? 110.954 92.890  94.172  1.00 2.37  ? 4   DC  F N4    1 
ATOM   6101 C  C5    . DC  E 4 4   ? 110.714 93.553  96.451  1.00 2.37  ? 4   DC  F C5    1 
ATOM   6102 C  C6    . DC  E 4 4   ? 110.054 93.368  97.589  1.00 2.37  ? 4   DC  F C6    1 
ATOM   6103 P  P     . DA  E 4 5   ? 109.343 89.784  102.733 1.00 2.37  ? 5   DA  F P     1 
ATOM   6104 O  OP1   . DA  E 4 5   ? 108.728 89.311  103.977 1.00 2.37  ? 5   DA  F OP1   1 
ATOM   6105 O  OP2   . DA  E 4 5   ? 110.771 90.115  102.698 1.00 2.37  ? 5   DA  F OP2   1 
ATOM   6106 O  "O5'" . DA  E 4 5   ? 109.042 88.689  101.614 1.00 2.37  ? 5   DA  F "O5'" 1 
ATOM   6107 C  "C5'" . DA  E 4 5   ? 107.738 88.123  101.444 1.00 2.37  ? 5   DA  F "C5'" 1 
ATOM   6108 C  "C4'" . DA  E 4 5   ? 107.747 87.135  100.293 1.00 2.37  ? 5   DA  F "C4'" 1 
ATOM   6109 O  "O4'" . DA  E 4 5   ? 108.045 87.783  99.038  1.00 2.37  ? 5   DA  F "O4'" 1 
ATOM   6110 C  "C3'" . DA  E 4 5   ? 108.806 86.047  100.454 1.00 2.37  ? 5   DA  F "C3'" 1 
ATOM   6111 O  "O3'" . DA  E 4 5   ? 108.256 84.811  100.220 1.00 2.37  ? 5   DA  F "O3'" 1 
ATOM   6112 C  "C2'" . DA  E 4 5   ? 109.812 86.364  99.361  1.00 2.37  ? 5   DA  F "C2'" 1 
ATOM   6113 C  "C1'" . DA  E 4 5   ? 108.898 86.934  98.325  1.00 2.37  ? 5   DA  F "C1'" 1 
ATOM   6114 N  N9    . DA  E 4 5   ? 109.565 87.651  97.260  1.00 2.37  ? 5   DA  F N9    1 
ATOM   6115 C  C8    . DA  E 4 5   ? 110.393 88.711  97.386  1.00 2.37  ? 5   DA  F C8    1 
ATOM   6116 N  N7    . DA  E 4 5   ? 110.892 89.128  96.255  1.00 2.37  ? 5   DA  F N7    1 
ATOM   6117 C  C5    . DA  E 4 5   ? 110.402 88.240  95.331  1.00 2.37  ? 5   DA  F C5    1 
ATOM   6118 C  C6    . DA  E 4 5   ? 110.583 88.123  93.948  1.00 2.37  ? 5   DA  F C6    1 
ATOM   6119 N  N6    . DA  E 4 5   ? 111.328 88.954  93.239  1.00 2.37  ? 5   DA  F N6    1 
ATOM   6120 N  N1    . DA  E 4 5   ? 109.965 87.114  93.320  1.00 2.37  ? 5   DA  F N1    1 
ATOM   6121 C  C2    . DA  E 4 5   ? 109.218 86.268  94.035  1.00 2.37  ? 5   DA  F C2    1 
ATOM   6122 N  N3    . DA  E 4 5   ? 108.978 86.271  95.345  1.00 2.37  ? 5   DA  F N3    1 
ATOM   6123 C  C4    . DA  E 4 5   ? 109.604 87.300  95.938  1.00 2.37  ? 5   DA  F C4    1 
ATOM   6124 P  P     . DT  E 4 6   ? 107.633 83.993  101.429 1.00 2.37  ? 6   DT  F P     1 
ATOM   6125 O  OP1   . DT  E 4 6   ? 106.863 82.874  100.859 1.00 2.37  ? 6   DT  F OP1   1 
ATOM   6126 O  OP2   . DT  E 4 6   ? 107.027 84.950  102.353 1.00 2.37  ? 6   DT  F OP2   1 
ATOM   6127 O  "O5'" . DT  E 4 6   ? 108.921 83.419  102.154 1.00 2.37  ? 6   DT  F "O5'" 1 
ATOM   6128 C  "C5'" . DT  E 4 6   ? 109.665 82.393  101.575 1.00 2.37  ? 6   DT  F "C5'" 1 
ATOM   6129 C  "C4'" . DT  E 4 6   ? 110.903 82.140  102.398 1.00 2.37  ? 6   DT  F "C4'" 1 
ATOM   6130 O  "O4'" . DT  E 4 6   ? 111.777 83.264  102.384 1.00 2.37  ? 6   DT  F "O4'" 1 
ATOM   6131 C  "C3'" . DT  E 4 6   ? 110.640 81.857  103.862 1.00 2.37  ? 6   DT  F "C3'" 1 
ATOM   6132 O  "O3'" . DT  E 4 6   ? 110.582 80.470  104.023 1.00 2.37  ? 6   DT  F "O3'" 1 
ATOM   6133 C  "C2'" . DT  E 4 6   ? 111.812 82.528  104.600 1.00 2.37  ? 6   DT  F "C2'" 1 
ATOM   6134 C  "C1'" . DT  E 4 6   ? 112.651 83.112  103.469 1.00 2.37  ? 6   DT  F "C1'" 1 
ATOM   6135 N  N1    . DT  E 4 6   ? 113.301 84.441  103.746 1.00 2.37  ? 6   DT  F N1    1 
ATOM   6136 C  C2    . DT  E 4 6   ? 114.674 84.548  103.671 1.00 2.37  ? 6   DT  F C2    1 
ATOM   6137 O  O2    . DT  E 4 6   ? 115.399 83.611  103.429 1.00 2.37  ? 6   DT  F O2    1 
ATOM   6138 N  N3    . DT  E 4 6   ? 115.165 85.794  103.911 1.00 2.37  ? 6   DT  F N3    1 
ATOM   6139 C  C4    . DT  E 4 6   ? 114.439 86.924  104.197 1.00 2.37  ? 6   DT  F C4    1 
ATOM   6140 O  O4    . DT  E 4 6   ? 114.962 88.006  104.394 1.00 2.37  ? 6   DT  F O4    1 
ATOM   6141 C  C5    . DT  E 4 6   ? 113.019 86.751  104.242 1.00 2.37  ? 6   DT  F C5    1 
ATOM   6142 C  C7    . DT  E 4 6   ? 112.142 87.917  104.544 1.00 2.37  ? 6   DT  F C7    1 
ATOM   6143 C  C6    . DT  E 4 6   ? 112.521 85.531  104.009 1.00 2.37  ? 6   DT  F C6    1 
ATOM   6144 P  P     . DC  E 4 7   ? 110.453 79.776  105.452 1.00 2.37  ? 7   DC  F P     1 
ATOM   6145 O  OP1   . DC  E 4 7   ? 109.789 78.497  105.251 1.00 2.37  ? 7   DC  F OP1   1 
ATOM   6146 O  OP2   . DC  E 4 7   ? 109.894 80.742  106.405 1.00 2.37  ? 7   DC  F OP2   1 
ATOM   6147 O  "O5'" . DC  E 4 7   ? 111.951 79.520  105.901 1.00 2.37  ? 7   DC  F "O5'" 1 
ATOM   6148 C  "C5'" . DC  E 4 7   ? 112.913 79.052  104.984 1.00 2.37  ? 7   DC  F "C5'" 1 
ATOM   6149 C  "C4'" . DC  E 4 7   ? 114.312 79.280  105.536 1.00 2.37  ? 7   DC  F "C4'" 1 
ATOM   6150 O  "O4'" . DC  E 4 7   ? 114.640 80.670  105.618 1.00 2.37  ? 7   DC  F "O4'" 1 
ATOM   6151 C  "C3'" . DC  E 4 7   ? 114.547 78.698  106.909 1.00 2.37  ? 7   DC  F "C3'" 1 
ATOM   6152 O  "O3'" . DC  E 4 7   ? 115.598 77.788  106.776 1.00 2.37  ? 7   DC  F "O3'" 1 
ATOM   6153 C  "C2'" . DC  E 4 7   ? 114.866 79.911  107.796 1.00 2.37  ? 7   DC  F "C2'" 1 
ATOM   6154 C  "C1'" . DC  E 4 7   ? 115.372 80.913  106.794 1.00 2.37  ? 7   DC  F "C1'" 1 
ATOM   6155 N  N1    . DC  E 4 7   ? 115.139 82.342  107.118 1.00 2.37  ? 7   DC  F N1    1 
ATOM   6156 C  C2    . DC  E 4 7   ? 116.199 83.254  107.086 1.00 2.37  ? 7   DC  F C2    1 
ATOM   6157 O  O2    . DC  E 4 7   ? 117.349 82.838  106.939 1.00 2.37  ? 7   DC  F O2    1 
ATOM   6158 N  N3    . DC  E 4 7   ? 115.946 84.561  107.297 1.00 2.37  ? 7   DC  F N3    1 
ATOM   6159 C  C4    . DC  E 4 7   ? 114.703 84.973  107.448 1.00 2.37  ? 7   DC  F C4    1 
ATOM   6160 N  N4    . DC  E 4 7   ? 114.499 86.274  107.639 1.00 2.37  ? 7   DC  F N4    1 
ATOM   6161 C  C5    . DC  E 4 7   ? 113.608 84.071  107.426 1.00 2.37  ? 7   DC  F C5    1 
ATOM   6162 C  C6    . DC  E 4 7   ? 113.868 82.784  107.238 1.00 2.37  ? 7   DC  F C6    1 
ATOM   6163 P  P     . DG  E 4 8   ? 116.074 76.835  107.962 1.00 2.37  ? 8   DG  F P     1 
ATOM   6164 O  OP1   . DG  E 4 8   ? 116.501 75.567  107.348 1.00 2.37  ? 8   DG  F OP1   1 
ATOM   6165 O  OP2   . DG  E 4 8   ? 115.007 76.806  108.975 1.00 2.37  ? 8   DG  F OP2   1 
ATOM   6166 O  "O5'" . DG  E 4 8   ? 117.329 77.605  108.555 1.00 2.37  ? 8   DG  F "O5'" 1 
ATOM   6167 C  "C5'" . DG  E 4 8   ? 118.489 77.770  107.769 1.00 2.37  ? 8   DG  F "C5'" 1 
ATOM   6168 C  "C4'" . DG  E 4 8   ? 119.516 78.593  108.520 1.00 2.37  ? 8   DG  F "C4'" 1 
ATOM   6169 O  "O4'" . DG  E 4 8   ? 119.066 79.952  108.711 1.00 2.37  ? 8   DG  F "O4'" 1 
ATOM   6170 C  "C3'" . DG  E 4 8   ? 119.859 78.051  109.888 1.00 2.37  ? 8   DG  F "C3'" 1 
ATOM   6171 O  "O3'" . DG  E 4 8   ? 121.266 78.082  110.022 1.00 2.37  ? 8   DG  F "O3'" 1 
ATOM   6172 C  "C2'" . DG  E 4 8   ? 119.120 78.992  110.848 1.00 2.37  ? 8   DG  F "C2'" 1 
ATOM   6173 C  "C1'" . DG  E 4 8   ? 119.133 80.295  110.073 1.00 2.37  ? 8   DG  F "C1'" 1 
ATOM   6174 N  N9    . DG  E 4 8   ? 118.004 81.181  110.303 1.00 2.37  ? 8   DG  F N9    1 
ATOM   6175 C  C8    . DG  E 4 8   ? 116.696 80.830  110.456 1.00 2.37  ? 8   DG  F C8    1 
ATOM   6176 N  N7    . DG  E 4 8   ? 115.908 81.844  110.615 1.00 2.37  ? 8   DG  F N7    1 
ATOM   6177 C  C5    . DG  E 4 8   ? 116.753 82.930  110.604 1.00 2.37  ? 8   DG  F C5    1 
ATOM   6178 C  C6    . DG  E 4 8   ? 116.473 84.291  110.769 1.00 2.37  ? 8   DG  F C6    1 
ATOM   6179 O  O6    . DG  E 4 8   ? 115.382 84.834  110.942 1.00 2.37  ? 8   DG  F O6    1 
ATOM   6180 N  N1    . DG  E 4 8   ? 117.620 85.058  110.706 1.00 2.37  ? 8   DG  F N1    1 
ATOM   6181 C  C2    . DG  E 4 8   ? 118.874 84.561  110.517 1.00 2.37  ? 8   DG  F C2    1 
ATOM   6182 N  N2    . DG  E 4 8   ? 119.868 85.453  110.488 1.00 2.37  ? 8   DG  F N2    1 
ATOM   6183 N  N3    . DG  E 4 8   ? 119.145 83.288  110.362 1.00 2.37  ? 8   DG  F N3    1 
ATOM   6184 C  C4    . DG  E 4 8   ? 118.043 82.535  110.417 1.00 2.37  ? 8   DG  F C4    1 
ATOM   6185 P  P     . DA  E 4 9   ? 122.018 77.480  111.302 1.00 2.37  ? 9   DA  F P     1 
ATOM   6186 O  OP1   . DA  E 4 9   ? 123.316 76.999  110.798 1.00 2.37  ? 9   DA  F OP1   1 
ATOM   6187 O  OP2   . DA  E 4 9   ? 121.119 76.541  112.005 1.00 2.37  ? 9   DA  F OP2   1 
ATOM   6188 O  "O5'" . DA  E 4 9   ? 122.275 78.739  112.240 1.00 2.37  ? 9   DA  F "O5'" 1 
ATOM   6189 C  "C5'" . DA  E 4 9   ? 123.215 79.701  111.820 1.00 2.37  ? 9   DA  F "C5'" 1 
ATOM   6190 C  "C4'" . DA  E 4 9   ? 123.277 80.887  112.759 1.00 2.37  ? 9   DA  F "C4'" 1 
ATOM   6191 O  "O4'" . DA  E 4 9   ? 122.050 81.657  112.750 1.00 2.37  ? 9   DA  F "O4'" 1 
ATOM   6192 C  "C3'" . DA  E 4 9   ? 123.564 80.534  114.215 1.00 2.37  ? 9   DA  F "C3'" 1 
ATOM   6193 O  "O3'" . DA  E 4 9   ? 124.728 81.269  114.614 1.00 2.37  ? 9   DA  F "O3'" 1 
ATOM   6194 C  "C2'" . DA  E 4 9   ? 122.264 80.926  114.949 1.00 2.37  ? 9   DA  F "C2'" 1 
ATOM   6195 C  "C1'" . DA  E 4 9   ? 121.732 82.035  114.068 1.00 2.37  ? 9   DA  F "C1'" 1 
ATOM   6196 N  N9    . DA  E 4 9   ? 120.284 82.224  114.120 1.00 2.37  ? 9   DA  F N9    1 
ATOM   6197 C  C8    . DA  E 4 9   ? 119.320 81.255  114.133 1.00 2.37  ? 9   DA  F C8    1 
ATOM   6198 N  N7    . DA  E 4 9   ? 118.097 81.730  114.160 1.00 2.37  ? 9   DA  F N7    1 
ATOM   6199 C  C5    . DA  E 4 9   ? 118.279 83.098  114.188 1.00 2.37  ? 9   DA  F C5    1 
ATOM   6200 C  C6    . DA  E 4 9   ? 117.378 84.169  114.227 1.00 2.37  ? 9   DA  F C6    1 
ATOM   6201 N  N6    . DA  E 4 9   ? 116.059 84.013  114.242 1.00 2.37  ? 9   DA  F N6    1 
ATOM   6202 N  N1    . DA  E 4 9   ? 117.885 85.416  114.242 1.00 2.37  ? 9   DA  F N1    1 
ATOM   6203 C  C2    . DA  E 4 9   ? 119.205 85.569  114.217 1.00 2.37  ? 9   DA  F C2    1 
ATOM   6204 N  N3    . DA  E 4 9   ? 120.154 84.634  114.182 1.00 2.37  ? 9   DA  F N3    1 
ATOM   6205 C  C4    . DA  E 4 9   ? 119.618 83.414  114.167 1.00 2.37  ? 9   DA  F C4    1 
ATOM   6206 P  P     . DA  E 4 10  ? 125.160 81.464  116.147 1.00 5.48  ? 10  DA  F P     1 
ATOM   6207 O  OP1   . DA  E 4 10  ? 126.625 81.610  116.160 1.00 5.48  ? 10  DA  F OP1   1 
ATOM   6208 O  OP2   . DA  E 4 10  ? 124.521 80.427  116.985 1.00 5.48  ? 10  DA  F OP2   1 
ATOM   6209 O  "O5'" . DA  E 4 10  ? 124.558 82.888  116.524 1.00 5.48  ? 10  DA  F "O5'" 1 
ATOM   6210 C  "C5'" . DA  E 4 10  ? 125.096 84.044  115.880 1.00 5.48  ? 10  DA  F "C5'" 1 
ATOM   6211 C  "C4'" . DA  E 4 10  ? 124.712 85.316  116.597 1.00 5.48  ? 10  DA  F "C4'" 1 
ATOM   6212 O  "O4'" . DA  E 4 10  ? 123.287 85.541  116.519 1.00 5.48  ? 10  DA  F "O4'" 1 
ATOM   6213 C  "C3'" . DA  E 4 10  ? 125.067 85.315  118.079 1.00 5.48  ? 10  DA  F "C3'" 1 
ATOM   6214 O  "O3'" . DA  E 4 10  ? 125.535 86.604  118.450 1.00 5.48  ? 10  DA  F "O3'" 1 
ATOM   6215 C  "C2'" . DA  E 4 10  ? 123.760 84.917  118.767 1.00 5.48  ? 10  DA  F "C2'" 1 
ATOM   6216 C  "C1'" . DA  E 4 10  ? 122.704 85.427  117.798 1.00 5.48  ? 10  DA  F "C1'" 1 
ATOM   6217 N  N9    . DA  E 4 10  ? 121.510 84.601  117.702 1.00 5.48  ? 10  DA  F N9    1 
ATOM   6218 C  C8    . DA  E 4 10  ? 121.421 83.237  117.729 1.00 5.48  ? 10  DA  F C8    1 
ATOM   6219 N  N7    . DA  E 4 10  ? 120.190 82.792  117.627 1.00 5.48  ? 10  DA  F N7    1 
ATOM   6220 C  C5    . DA  E 4 10  ? 119.430 83.950  117.552 1.00 5.48  ? 10  DA  F C5    1 
ATOM   6221 C  C6    . DA  E 4 10  ? 118.052 84.180  117.439 1.00 5.48  ? 10  DA  F C6    1 
ATOM   6222 N  N6    . DA  E 4 10  ? 117.146 83.204  117.378 1.00 5.48  ? 10  DA  F N6    1 
ATOM   6223 N  N1    . DA  E 4 10  ? 117.633 85.465  117.388 1.00 5.48  ? 10  DA  F N1    1 
ATOM   6224 C  C2    . DA  E 4 10  ? 118.540 86.432  117.445 1.00 5.48  ? 10  DA  F C2    1 
ATOM   6225 N  N3    . DA  E 4 10  ? 119.852 86.338  117.551 1.00 5.48  ? 10  DA  F N3    1 
ATOM   6226 C  C4    . DA  E 4 10  ? 120.234 85.062  117.601 1.00 5.48  ? 10  DA  F C4    1 
ATOM   6227 P  P     . DA  E 4 11  ? 125.891 86.966  119.970 1.00 17.18 ? 11  DA  F P     1 
ATOM   6228 O  OP1   . DA  E 4 11  ? 126.920 88.023  119.925 1.00 17.18 ? 11  DA  F OP1   1 
ATOM   6229 O  OP2   . DA  E 4 11  ? 126.157 85.705  120.701 1.00 17.18 ? 11  DA  F OP2   1 
ATOM   6230 O  "O5'" . DA  E 4 11  ? 124.544 87.591  120.559 1.00 17.18 ? 11  DA  F "O5'" 1 
ATOM   6231 C  "C5'" . DA  E 4 11  ? 124.004 88.767  119.965 1.00 17.18 ? 11  DA  F "C5'" 1 
ATOM   6232 C  "C4'" . DA  E 4 11  ? 122.580 88.997  120.425 1.00 17.18 ? 11  DA  F "C4'" 1 
ATOM   6233 O  "O4'" . DA  E 4 11  ? 121.755 87.845  120.168 1.00 17.18 ? 11  DA  F "O4'" 1 
ATOM   6234 C  "C3'" . DA  E 4 11  ? 122.429 89.288  121.920 1.00 17.18 ? 11  DA  F "C3'" 1 
ATOM   6235 O  "O3'" . DA  E 4 11  ? 122.191 90.673  122.074 1.00 17.18 ? 11  DA  F "O3'" 1 
ATOM   6236 C  "C2'" . DA  E 4 11  ? 121.251 88.396  122.377 1.00 17.18 ? 11  DA  F "C2'" 1 
ATOM   6237 C  "C1'" . DA  E 4 11  ? 120.675 87.911  121.056 1.00 17.18 ? 11  DA  F "C1'" 1 
ATOM   6238 N  N9    . DA  E 4 11  ? 120.023 86.607  121.095 1.00 17.18 ? 11  DA  F N9    1 
ATOM   6239 C  C8    . DA  E 4 11  ? 120.615 85.389  121.237 1.00 17.18 ? 11  DA  F C8    1 
ATOM   6240 N  N7    . DA  E 4 11  ? 119.769 84.384  121.224 1.00 17.18 ? 11  DA  F N7    1 
ATOM   6241 C  C5    . DA  E 4 11  ? 118.539 84.992  121.097 1.00 17.18 ? 11  DA  F C5    1 
ATOM   6242 C  C6    . DA  E 4 11  ? 117.231 84.482  121.033 1.00 17.18 ? 11  DA  F C6    1 
ATOM   6243 N  N6    . DA  E 4 11  ? 116.944 83.182  121.090 1.00 17.18 ? 11  DA  F N6    1 
ATOM   6244 N  N1    . DA  E 4 11  ? 116.221 85.368  120.897 1.00 17.18 ? 11  DA  F N1    1 
ATOM   6245 C  C2    . DA  E 4 11  ? 116.513 86.667  120.831 1.00 17.18 ? 11  DA  F C2    1 
ATOM   6246 N  N3    . DA  E 4 11  ? 117.700 87.260  120.882 1.00 17.18 ? 11  DA  F N3    1 
ATOM   6247 C  C4    . DA  E 4 11  ? 118.677 86.361  121.019 1.00 17.18 ? 11  DA  F C4    1 
ATOM   6248 P  P     . DC  E 4 12  ? 121.952 91.330  123.517 1.00 26.83 ? 12  DC  F P     1 
ATOM   6249 O  OP1   . DC  E 4 12  ? 122.253 92.769  123.395 1.00 26.83 ? 12  DC  F OP1   1 
ATOM   6250 O  OP2   . DC  E 4 12  ? 122.674 90.525  124.526 1.00 26.83 ? 12  DC  F OP2   1 
ATOM   6251 O  "O5'" . DC  E 4 12  ? 120.378 91.174  123.753 1.00 26.83 ? 12  DC  F "O5'" 1 
ATOM   6252 C  "C5'" . DC  E 4 12  ? 119.474 91.786  122.838 1.00 26.83 ? 12  DC  F "C5'" 1 
ATOM   6253 C  "C4'" . DC  E 4 12  ? 118.036 91.416  123.149 1.00 26.83 ? 12  DC  F "C4'" 1 
ATOM   6254 O  "O4'" . DC  E 4 12  ? 117.805 90.001  122.988 1.00 26.83 ? 12  DC  F "O4'" 1 
ATOM   6255 C  "C3'" . DC  E 4 12  ? 117.587 91.782  124.559 1.00 26.83 ? 12  DC  F "C3'" 1 
ATOM   6256 O  "O3'" . DC  E 4 12  ? 116.507 92.716  124.451 1.00 26.83 ? 12  DC  F "O3'" 1 
ATOM   6257 C  "C2'" . DC  E 4 12  ? 117.191 90.430  125.200 1.00 26.83 ? 12  DC  F "C2'" 1 
ATOM   6258 C  "C1'" . DC  E 4 12  ? 116.906 89.567  123.980 1.00 26.83 ? 12  DC  F "C1'" 1 
ATOM   6259 N  N1    . DC  E 4 12  ? 117.115 88.093  124.148 1.00 26.83 ? 12  DC  F N1    1 
ATOM   6260 C  C2    . DC  E 4 12  ? 116.033 87.209  124.002 1.00 26.83 ? 12  DC  F C2    1 
ATOM   6261 O  O2    . DC  E 4 12  ? 114.899 87.666  123.833 1.00 26.83 ? 12  DC  F O2    1 
ATOM   6262 N  N3    . DC  E 4 12  ? 116.257 85.873  124.092 1.00 26.83 ? 12  DC  F N3    1 
ATOM   6263 C  C4    . DC  E 4 12  ? 117.492 85.422  124.280 1.00 26.83 ? 12  DC  F C4    1 
ATOM   6264 N  N4    . DC  E 4 12  ? 117.666 84.100  124.366 1.00 26.83 ? 12  DC  F N4    1 
ATOM   6265 C  C5    . DC  E 4 12  ? 118.607 86.304  124.392 1.00 26.83 ? 12  DC  F C5    1 
ATOM   6266 C  C6    . DC  E 4 12  ? 118.376 87.613  124.302 1.00 26.83 ? 12  DC  F C6    1 
ATOM   6267 P  P     . DC  E 4 13  ? 115.939 93.521  125.718 1.00 35.93 ? 13  DC  F P     1 
ATOM   6268 O  OP1   . DC  E 4 13  ? 115.265 94.714  125.155 1.00 35.93 ? 13  DC  F OP1   1 
ATOM   6269 O  OP2   . DC  E 4 13  ? 117.030 93.708  126.702 1.00 35.93 ? 13  DC  F OP2   1 
ATOM   6270 O  "O5'" . DC  E 4 13  ? 114.838 92.550  126.346 1.00 35.93 ? 13  DC  F "O5'" 1 
ATOM   6271 C  "C5'" . DC  E 4 13  ? 113.637 92.311  125.632 1.00 35.93 ? 13  DC  F "C5'" 1 
ATOM   6272 C  "C4'" . DC  E 4 13  ? 112.915 91.076  126.147 1.00 35.93 ? 13  DC  F "C4'" 1 
ATOM   6273 O  "O4'" . DC  E 4 13  ? 113.713 89.896  126.025 1.00 35.93 ? 13  DC  F "O4'" 1 
ATOM   6274 C  "C3'" . DC  E 4 13  ? 112.535 91.121  127.612 1.00 35.93 ? 13  DC  F "C3'" 1 
ATOM   6275 O  "O3'" . DC  E 4 13  ? 111.237 91.674  127.741 1.00 35.93 ? 13  DC  F "O3'" 1 
ATOM   6276 C  "C2'" . DC  E 4 13  ? 112.617 89.651  128.083 1.00 35.93 ? 13  DC  F "C2'" 1 
ATOM   6277 C  "C1'" . DC  E 4 13  ? 113.107 88.923  126.841 1.00 35.93 ? 13  DC  F "C1'" 1 
ATOM   6278 N  N1    . DC  E 4 13  ? 114.058 87.780  127.042 1.00 35.93 ? 13  DC  F N1    1 
ATOM   6279 C  C2    . DC  E 4 13  ? 113.570 86.473  126.962 1.00 35.93 ? 13  DC  F C2    1 
ATOM   6280 O  O2    . DC  E 4 13  ? 112.361 86.296  126.771 1.00 35.93 ? 13  DC  F O2    1 
ATOM   6281 N  N3    . DC  E 4 13  ? 114.434 85.440  127.078 1.00 35.93 ? 13  DC  F N3    1 
ATOM   6282 C  C4    . DC  E 4 13  ? 115.729 85.677  127.272 1.00 35.93 ? 13  DC  F C4    1 
ATOM   6283 N  N4    . DC  E 4 13  ? 116.537 84.628  127.388 1.00 35.93 ? 13  DC  F N4    1 
ATOM   6284 C  C5    . DC  E 4 13  ? 116.250 87.002  127.359 1.00 35.93 ? 13  DC  F C5    1 
ATOM   6285 C  C6    . DC  E 4 13  ? 115.389 88.015  127.227 1.00 35.93 ? 13  DC  F C6    1 
ATOM   6286 P  P     . DA  E 4 14  ? 110.624 91.940  129.196 1.00 40.46 ? 14  DA  F P     1 
ATOM   6287 O  OP1   . DA  E 4 14  ? 109.660 93.059  129.073 1.00 40.46 ? 14  DA  F OP1   1 
ATOM   6288 O  OP2   . DA  E 4 14  ? 111.749 92.077  130.140 1.00 40.46 ? 14  DA  F OP2   1 
ATOM   6289 O  "O5'" . DA  E 4 14  ? 109.834 90.594  129.556 1.00 40.46 ? 14  DA  F "O5'" 1 
ATOM   6290 C  "C5'" . DA  E 4 14  ? 108.657 90.249  128.845 1.00 40.46 ? 14  DA  F "C5'" 1 
ATOM   6291 C  "C4'" . DA  E 4 14  ? 108.120 88.883  129.261 1.00 40.46 ? 14  DA  F "C4'" 1 
ATOM   6292 O  "O4'" . DA  E 4 14  ? 109.146 87.870  129.056 1.00 40.46 ? 14  DA  F "O4'" 1 
ATOM   6293 C  "C3'" . DA  E 4 14  ? 107.739 88.781  130.739 1.00 40.46 ? 14  DA  F "C3'" 1 
ATOM   6294 O  "O3'" . DA  E 4 14  ? 106.680 87.849  130.916 1.00 40.46 ? 14  DA  F "O3'" 1 
ATOM   6295 C  "C2'" . DA  E 4 14  ? 109.008 88.251  131.382 1.00 40.46 ? 14  DA  F "C2'" 1 
ATOM   6296 C  "C1'" . DA  E 4 14  ? 109.490 87.295  130.305 1.00 40.46 ? 14  DA  F "C1'" 1 
ATOM   6297 N  N9    . DA  E 4 14  ? 110.914 86.996  130.356 1.00 40.46 ? 14  DA  F N9    1 
ATOM   6298 C  C8    . DA  E 4 14  ? 111.937 87.864  130.606 1.00 40.46 ? 14  DA  F C8    1 
ATOM   6299 N  N7    . DA  E 4 14  ? 113.120 87.294  130.612 1.00 40.46 ? 14  DA  F N7    1 
ATOM   6300 C  C5    . DA  E 4 14  ? 112.842 85.952  130.398 1.00 40.46 ? 14  DA  F C5    1 
ATOM   6301 C  C6    . DA  E 4 14  ? 113.663 84.816  130.303 1.00 40.46 ? 14  DA  F C6    1 
ATOM   6302 N  N6    . DA  E 4 14  ? 114.986 84.860  130.427 1.00 40.46 ? 14  DA  F N6    1 
ATOM   6303 N  N1    . DA  E 4 14  ? 113.068 83.627  130.081 1.00 40.46 ? 14  DA  F N1    1 
ATOM   6304 C  C2    . DA  E 4 14  ? 111.739 83.588  129.963 1.00 40.46 ? 14  DA  F C2    1 
ATOM   6305 N  N3    . DA  E 4 14  ? 110.865 84.591  130.029 1.00 40.46 ? 14  DA  F N3    1 
ATOM   6306 C  C4    . DA  E 4 14  ? 111.488 85.753  130.250 1.00 40.46 ? 14  DA  F C4    1 
ATOM   6307 P  P     . DC  E 4 15  ? 105.765 87.921  132.233 1.00 41.39 ? 15  DC  F P     1 
ATOM   6308 O  OP1   . DC  E 4 15  ? 105.023 89.195  132.147 1.00 41.39 ? 15  DC  F OP1   1 
ATOM   6309 O  OP2   . DC  E 4 15  ? 106.606 87.652  133.418 1.00 41.39 ? 15  DC  F OP2   1 
ATOM   6310 O  "O5'" . DC  E 4 15  ? 104.699 86.738  132.058 1.00 41.39 ? 15  DC  F "O5'" 1 
ATOM   6311 C  "C5'" . DC  E 4 15  ? 105.049 85.433  131.549 1.00 41.39 ? 15  DC  F "C5'" 1 
ATOM   6312 C  "C4'" . DC  E 4 15  ? 105.951 84.629  132.492 1.00 41.39 ? 15  DC  F "C4'" 1 
ATOM   6313 O  "O4'" . DC  E 4 15  ? 107.333 85.032  132.440 1.00 41.39 ? 15  DC  F "O4'" 1 
ATOM   6314 C  "C3'" . DC  E 4 15  ? 105.568 84.651  133.973 1.00 41.39 ? 15  DC  F "C3'" 1 
ATOM   6315 O  "O3'" . DC  E 4 15  ? 104.746 83.536  134.280 1.00 41.39 ? 15  DC  F "O3'" 1 
ATOM   6316 C  "C2'" . DC  E 4 15  ? 106.930 84.587  134.710 1.00 41.39 ? 15  DC  F "C2'" 1 
ATOM   6317 C  "C1'" . DC  E 4 15  ? 107.935 84.441  133.563 1.00 41.39 ? 15  DC  F "C1'" 1 
ATOM   6318 N  N1    . DC  E 4 15  ? 109.307 85.025  133.807 1.00 41.39 ? 15  DC  F N1    1 
ATOM   6319 C  C2    . DC  E 4 15  ? 110.439 84.223  133.600 1.00 41.39 ? 15  DC  F C2    1 
ATOM   6320 O  O2    . DC  E 4 15  ? 110.282 83.055  133.251 1.00 41.39 ? 15  DC  F O2    1 
ATOM   6321 N  N3    . DC  E 4 15  ? 111.673 84.749  133.813 1.00 41.39 ? 15  DC  F N3    1 
ATOM   6322 C  C4    . DC  E 4 15  ? 111.795 86.019  134.192 1.00 41.39 ? 15  DC  F C4    1 
ATOM   6323 N  N4    . DC  E 4 15  ? 113.027 86.501  134.384 1.00 41.39 ? 15  DC  F N4    1 
ATOM   6324 C  C5    . DC  E 4 15  ? 110.657 86.854  134.394 1.00 41.39 ? 15  DC  F C5    1 
ATOM   6325 C  C6    . DC  E 4 15  ? 109.445 86.325  134.188 1.00 41.39 ? 15  DC  F C6    1 
ATOM   6326 P  P     . DG  F 5 12  ? 117.939 75.116  136.961 1.00 90.38 ? -23 DG  E P     1 
ATOM   6327 O  OP1   . DG  F 5 12  ? 116.782 75.071  137.882 1.00 93.41 ? -23 DG  E OP1   1 
ATOM   6328 O  OP2   . DG  F 5 12  ? 118.390 73.865  136.316 1.00 86.21 ? -23 DG  E OP2   1 
ATOM   6329 O  "O5'" . DG  F 5 12  ? 117.687 76.170  135.776 1.00 89.23 ? -23 DG  E "O5'" 1 
ATOM   6330 C  "C5'" . DG  F 5 12  ? 116.681 75.903  134.803 1.00 87.67 ? -23 DG  E "C5'" 1 
ATOM   6331 C  "C4'" . DG  F 5 12  ? 116.776 76.855  133.611 1.00 87.13 ? -23 DG  E "C4'" 1 
ATOM   6332 O  "O4'" . DG  F 5 12  ? 116.432 78.218  133.971 1.00 88.07 ? -23 DG  E "O4'" 1 
ATOM   6333 C  "C3'" . DG  F 5 12  ? 118.150 76.931  132.918 1.00 89.66 ? -23 DG  E "C3'" 1 
ATOM   6334 O  "O3'" . DG  F 5 12  ? 118.020 76.524  131.558 1.00 90.17 ? -23 DG  E "O3'" 1 
ATOM   6335 C  "C2'" . DG  F 5 12  ? 118.495 78.436  132.991 1.00 91.60 ? -23 DG  E "C2'" 1 
ATOM   6336 C  "C1'" . DG  F 5 12  ? 117.097 79.025  133.046 1.00 90.40 ? -23 DG  E "C1'" 1 
ATOM   6337 N  N9    . DG  F 5 12  ? 116.989 80.443  133.409 1.00 93.06 ? -23 DG  E N9    1 
ATOM   6338 C  C8    . DG  F 5 12  ? 117.999 81.314  133.753 1.00 88.25 ? -23 DG  E C8    1 
ATOM   6339 N  N7    . DG  F 5 12  ? 117.574 82.526  133.996 1.00 94.99 ? -23 DG  E N7    1 
ATOM   6340 C  C5    . DG  F 5 12  ? 116.201 82.455  133.783 1.00 86.48 ? -23 DG  E C5    1 
ATOM   6341 C  C6    . DG  F 5 12  ? 115.196 83.457  133.883 1.00 92.91 ? -23 DG  E C6    1 
ATOM   6342 O  O6    . DG  F 5 12  ? 115.323 84.643  134.200 1.00 90.38 ? -23 DG  E O6    1 
ATOM   6343 N  N1    . DG  F 5 12  ? 113.931 82.954  133.578 1.00 91.79 ? -23 DG  E N1    1 
ATOM   6344 C  C2    . DG  F 5 12  ? 113.677 81.655  133.219 1.00 87.61 ? -23 DG  E C2    1 
ATOM   6345 N  N2    . DG  F 5 12  ? 112.402 81.344  132.954 1.00 88.19 ? -23 DG  E N2    1 
ATOM   6346 N  N3    . DG  F 5 12  ? 114.605 80.719  133.113 1.00 94.21 ? -23 DG  E N3    1 
ATOM   6347 C  C4    . DG  F 5 12  ? 115.835 81.185  133.408 1.00 95.89 ? -23 DG  E C4    1 
ATOM   6348 P  P     . DT  F 5 13  ? 118.175 74.982  131.125 1.00 89.05 ? -22 DT  E P     1 
ATOM   6349 O  OP1   . DT  F 5 13  ? 118.156 74.170  132.357 1.00 92.84 ? -22 DT  E OP1   1 
ATOM   6350 O  OP2   . DT  F 5 13  ? 119.293 74.856  130.169 1.00 94.68 ? -22 DT  E OP2   1 
ATOM   6351 O  "O5'" . DT  F 5 13  ? 116.838 74.671  130.303 1.00 94.86 ? -22 DT  E "O5'" 1 
ATOM   6352 C  "C5'" . DT  F 5 13  ? 115.607 74.406  130.964 1.00 86.77 ? -22 DT  E "C5'" 1 
ATOM   6353 C  "C4'" . DT  F 5 13  ? 114.493 75.305  130.437 1.00 86.31 ? -22 DT  E "C4'" 1 
ATOM   6354 O  "O4'" . DT  F 5 13  ? 114.735 76.687  130.739 1.00 87.62 ? -22 DT  E "O4'" 1 
ATOM   6355 C  "C3'" . DT  F 5 13  ? 114.272 75.237  128.931 1.00 94.70 ? -22 DT  E "C3'" 1 
ATOM   6356 O  "O3'" . DT  F 5 13  ? 113.213 74.329  128.643 1.00 86.90 ? -22 DT  E "O3'" 1 
ATOM   6357 C  "C2'" . DT  F 5 13  ? 113.949 76.692  128.517 1.00 90.13 ? -22 DT  E "C2'" 1 
ATOM   6358 C  "C1'" . DT  F 5 13  ? 113.990 77.468  129.835 1.00 95.50 ? -22 DT  E "C1'" 1 
ATOM   6359 N  N1    . DT  F 5 13  ? 114.609 78.842  129.793 1.00 91.25 ? -22 DT  E N1    1 
ATOM   6360 C  C2    . DT  F 5 13  ? 113.803 79.968  129.889 1.00 92.84 ? -22 DT  E C2    1 
ATOM   6361 O  O2    . DT  F 5 13  ? 112.585 79.924  129.925 1.00 89.07 ? -22 DT  E O2    1 
ATOM   6362 N  N3    . DT  F 5 13  ? 114.490 81.158  129.904 1.00 92.78 ? -22 DT  E N3    1 
ATOM   6363 C  C4    . DT  F 5 13  ? 115.859 81.334  129.862 1.00 94.26 ? -22 DT  E C4    1 
ATOM   6364 O  O4    . DT  F 5 13  ? 116.383 82.446  129.880 1.00 86.10 ? -22 DT  E O4    1 
ATOM   6365 C  C5    . DT  F 5 13  ? 116.635 80.119  129.792 1.00 93.42 ? -22 DT  E C5    1 
ATOM   6366 C  C7    . DT  F 5 13  ? 118.132 80.184  129.741 1.00 95.81 ? -22 DT  E C7    1 
ATOM   6367 C  C6    . DT  F 5 13  ? 115.981 78.951  129.773 1.00 93.40 ? -22 DT  E C6    1 
ATOM   6368 P  P     . DG  F 5 14  ? 112.855 73.936  127.126 1.00 73.67 ? -21 DG  E P     1 
ATOM   6369 O  OP1   . DG  F 5 14  ? 112.064 72.689  127.147 1.00 78.76 ? -21 DG  E OP1   1 
ATOM   6370 O  OP2   . DG  F 5 14  ? 114.104 73.980  126.336 1.00 71.90 ? -21 DG  E OP2   1 
ATOM   6371 O  "O5'" . DG  F 5 14  ? 111.853 75.092  126.673 1.00 75.35 ? -21 DG  E "O5'" 1 
ATOM   6372 C  "C5'" . DG  F 5 14  ? 110.604 75.208  127.337 1.00 79.95 ? -21 DG  E "C5'" 1 
ATOM   6373 C  "C4'" . DG  F 5 14  ? 109.823 76.422  126.866 1.00 73.80 ? -21 DG  E "C4'" 1 
ATOM   6374 O  "O4'" . DG  F 5 14  ? 110.504 77.660  127.207 1.00 73.75 ? -21 DG  E "O4'" 1 
ATOM   6375 C  "C3'" . DG  F 5 14  ? 109.569 76.453  125.368 1.00 72.17 ? -21 DG  E "C3'" 1 
ATOM   6376 O  "O3'" . DG  F 5 14  ? 108.180 76.700  125.128 1.00 71.06 ? -21 DG  E "O3'" 1 
ATOM   6377 C  "C2'" . DG  F 5 14  ? 110.507 77.556  124.852 1.00 77.66 ? -21 DG  E "C2'" 1 
ATOM   6378 C  "C1'" . DG  F 5 14  ? 110.669 78.466  126.060 1.00 72.98 ? -21 DG  E "C1'" 1 
ATOM   6379 N  N9    . DG  F 5 14  ? 111.987 79.110  126.171 1.00 73.52 ? -21 DG  E N9    1 
ATOM   6380 C  C8    . DG  F 5 14  ? 113.202 78.502  126.048 1.00 75.78 ? -21 DG  E C8    1 
ATOM   6381 N  N7    . DG  F 5 14  ? 114.214 79.304  126.210 1.00 71.40 ? -21 DG  E N7    1 
ATOM   6382 C  C5    . DG  F 5 14  ? 113.636 80.538  126.417 1.00 76.61 ? -21 DG  E C5    1 
ATOM   6383 C  C6    . DG  F 5 14  ? 114.245 81.792  126.644 1.00 72.33 ? -21 DG  E C6    1 
ATOM   6384 O  O6    . DG  F 5 14  ? 115.449 82.056  126.695 1.00 76.76 ? -21 DG  E O6    1 
ATOM   6385 N  N1    . DG  F 5 14  ? 113.308 82.795  126.809 1.00 77.87 ? -21 DG  E N1    1 
ATOM   6386 C  C2    . DG  F 5 14  ? 111.950 82.615  126.768 1.00 71.89 ? -21 DG  E C2    1 
ATOM   6387 N  N2    . DG  F 5 14  ? 111.206 83.718  126.944 1.00 75.01 ? -21 DG  E N2    1 
ATOM   6388 N  N3    . DG  F 5 14  ? 111.358 81.439  126.566 1.00 77.81 ? -21 DG  E N3    1 
ATOM   6389 C  C4    . DG  F 5 14  ? 112.262 80.447  126.395 1.00 75.01 ? -21 DG  E C4    1 
ATOM   6390 P  P     . DG  F 5 15  ? 107.596 76.792  123.635 1.00 53.17 ? -20 DG  E P     1 
ATOM   6391 O  OP1   . DG  F 5 15  ? 106.154 76.463  123.656 1.00 58.03 ? -20 DG  E OP1   1 
ATOM   6392 O  OP2   . DG  F 5 15  ? 108.486 75.972  122.781 1.00 59.31 ? -20 DG  E OP2   1 
ATOM   6393 O  "O5'" . DG  F 5 15  ? 107.763 78.340  123.279 1.00 57.82 ? -20 DG  E "O5'" 1 
ATOM   6394 C  "C5'" . DG  F 5 15  ? 107.075 79.296  124.064 1.00 62.12 ? -20 DG  E "C5'" 1 
ATOM   6395 C  "C4'" . DG  F 5 15  ? 107.538 80.711  123.754 1.00 58.54 ? -20 DG  E "C4'" 1 
ATOM   6396 O  "O4'" . DG  F 5 15  ? 108.933 80.885  124.088 1.00 61.71 ? -20 DG  E "O4'" 1 
ATOM   6397 C  "C3'" . DG  F 5 15  ? 107.395 81.146  122.291 1.00 54.05 ? -20 DG  E "C3'" 1 
ATOM   6398 O  "O3'" . DG  F 5 15  ? 106.481 82.234  122.232 1.00 54.07 ? -20 DG  E "O3'" 1 
ATOM   6399 C  "C2'" . DG  F 5 15  ? 108.827 81.515  121.859 1.00 60.75 ? -20 DG  E "C2'" 1 
ATOM   6400 C  "C1'" . DG  F 5 15  ? 109.478 81.818  123.191 1.00 56.65 ? -20 DG  E "C1'" 1 
ATOM   6401 N  N9    . DG  F 5 15  ? 110.928 81.661  123.217 1.00 54.33 ? -20 DG  E N9    1 
ATOM   6402 C  C8    . DG  F 5 15  ? 111.633 80.490  123.127 1.00 61.95 ? -20 DG  E C8    1 
ATOM   6403 N  N7    . DG  F 5 15  ? 112.919 80.653  123.208 1.00 56.15 ? -20 DG  E N7    1 
ATOM   6404 C  C5    . DG  F 5 15  ? 113.079 82.020  123.362 1.00 60.18 ? -20 DG  E C5    1 
ATOM   6405 C  C6    . DG  F 5 15  ? 114.255 82.784  123.502 1.00 59.93 ? -20 DG  E C6    1 
ATOM   6406 O  O6    . DG  F 5 15  ? 115.426 82.388  123.517 1.00 61.51 ? -20 DG  E O6    1 
ATOM   6407 N  N1    . DG  F 5 15  ? 113.977 84.135  123.636 1.00 58.91 ? -20 DG  E N1    1 
ATOM   6408 C  C2    . DG  F 5 15  ? 112.714 84.677  123.630 1.00 60.18 ? -20 DG  E C2    1 
ATOM   6409 N  N2    . DG  F 5 15  ? 112.638 86.005  123.762 1.00 56.16 ? -20 DG  E N2    1 
ATOM   6410 N  N3    . DG  F 5 15  ? 111.603 83.969  123.499 1.00 55.37 ? -20 DG  E N3    1 
ATOM   6411 C  C4    . DG  F 5 15  ? 111.863 82.654  123.366 1.00 61.63 ? -20 DG  E C4    1 
ATOM   6412 P  P     . DT  F 5 16  ? 106.126 82.980  120.856 1.00 33.67 ? -19 DT  E P     1 
ATOM   6413 O  OP1   . DT  F 5 16  ? 104.774 83.562  121.003 1.00 39.04 ? -19 DT  E OP1   1 
ATOM   6414 O  OP2   . DT  F 5 16  ? 106.403 82.064  119.732 1.00 36.03 ? -19 DT  E OP2   1 
ATOM   6415 O  "O5'" . DT  F 5 16  ? 107.170 84.184  120.792 1.00 35.61 ? -19 DT  E "O5'" 1 
ATOM   6416 C  "C5'" . DT  F 5 16  ? 107.133 85.178  121.805 1.00 30.54 ? -19 DT  E "C5'" 1 
ATOM   6417 C  "C4'" . DT  F 5 16  ? 108.178 86.258  121.570 1.00 38.89 ? -19 DT  E "C4'" 1 
ATOM   6418 O  "O4'" . DT  F 5 16  ? 109.522 85.716  121.612 1.00 33.89 ? -19 DT  E "O4'" 1 
ATOM   6419 C  "C3'" . DT  F 5 16  ? 108.059 86.981  120.238 1.00 35.18 ? -19 DT  E "C3'" 1 
ATOM   6420 O  "O3'" . DT  F 5 16  ? 108.170 88.370  120.497 1.00 33.47 ? -19 DT  E "O3'" 1 
ATOM   6421 C  "C2'" . DT  F 5 16  ? 109.225 86.411  119.416 1.00 31.76 ? -19 DT  E "C2'" 1 
ATOM   6422 C  "C1'" . DT  F 5 16  ? 110.247 86.205  120.504 1.00 38.43 ? -19 DT  E "C1'" 1 
ATOM   6423 N  N1    . DT  F 5 16  ? 111.330 85.236  120.223 1.00 35.13 ? -19 DT  E N1    1 
ATOM   6424 C  C2    . DT  F 5 16  ? 112.622 85.655  120.340 1.00 29.42 ? -19 DT  E C2    1 
ATOM   6425 O  O2    . DT  F 5 16  ? 112.924 86.812  120.541 1.00 35.56 ? -19 DT  E O2    1 
ATOM   6426 N  N3    . DT  F 5 16  ? 113.560 84.686  120.151 1.00 32.66 ? -19 DT  E N3    1 
ATOM   6427 C  C4    . DT  F 5 16  ? 113.339 83.346  119.915 1.00 34.66 ? -19 DT  E C4    1 
ATOM   6428 O  O4    . DT  F 5 16  ? 114.256 82.549  119.766 1.00 38.25 ? -19 DT  E O4    1 
ATOM   6429 C  C5    . DT  F 5 16  ? 111.956 82.956  119.849 1.00 32.96 ? -19 DT  E C5    1 
ATOM   6430 C  C7    . DT  F 5 16  ? 111.595 81.522  119.588 1.00 38.48 ? -19 DT  E C7    1 
ATOM   6431 C  C6    . DT  F 5 16  ? 111.024 83.907  120.027 1.00 35.63 ? -19 DT  E C6    1 
ATOM   6432 P  P     . DT  F 5 17  ? 107.959 89.468  119.350 1.00 9.83  ? -18 DT  E P     1 
ATOM   6433 O  OP1   . DT  F 5 17  ? 106.911 90.382  119.839 1.00 18.97 ? -18 DT  E OP1   1 
ATOM   6434 O  OP2   . DT  F 5 17  ? 107.770 88.785  118.059 1.00 16.58 ? -18 DT  E OP2   1 
ATOM   6435 O  "O5'" . DT  F 5 17  ? 109.336 90.273  119.335 1.00 19.64 ? -18 DT  E "O5'" 1 
ATOM   6436 C  "C5'" . DT  F 5 17  ? 110.579 89.600  119.212 1.00 11.39 ? -18 DT  E "C5'" 1 
ATOM   6437 C  "C4'" . DT  F 5 17  ? 111.689 90.618  119.033 1.00 11.04 ? -18 DT  E "C4'" 1 
ATOM   6438 O  "O4'" . DT  F 5 17  ? 112.991 89.988  118.983 1.00 19.00 ? -18 DT  E "O4'" 1 
ATOM   6439 C  "C3'" . DT  F 5 17  ? 111.595 91.405  117.753 1.00 16.64 ? -18 DT  E "C3'" 1 
ATOM   6440 O  "O3'" . DT  F 5 17  ? 112.190 92.661  117.974 1.00 10.33 ? -18 DT  E "O3'" 1 
ATOM   6441 C  "C2'" . DT  F 5 17  ? 112.361 90.519  116.756 1.00 17.23 ? -18 DT  E "C2'" 1 
ATOM   6442 C  "C1'" . DT  F 5 17  ? 113.421 89.859  117.640 1.00 17.21 ? -18 DT  E "C1'" 1 
ATOM   6443 N  N1    . DT  F 5 17  ? 113.673 88.411  117.396 1.00 18.90 ? -18 DT  E N1    1 
ATOM   6444 C  C2    . DT  F 5 17  ? 114.952 87.935  117.519 1.00 16.79 ? -18 DT  E C2    1 
ATOM   6445 O  O2    . DT  F 5 17  ? 115.911 88.653  117.730 1.00 10.91 ? -18 DT  E O2    1 
ATOM   6446 N  N3    . DT  F 5 17  ? 115.082 86.590  117.334 1.00 9.87  ? -18 DT  E N3    1 
ATOM   6447 C  C4    . DT  F 5 17  ? 114.088 85.686  117.096 1.00 9.93  ? -18 DT  E C4    1 
ATOM   6448 O  O4    . DT  F 5 17  ? 114.314 84.486  116.956 1.00 9.95  ? -18 DT  E O4    1 
ATOM   6449 C  C5    . DT  F 5 17  ? 112.764 86.241  117.014 1.00 12.13 ? -18 DT  E C5    1 
ATOM   6450 C  C7    . DT  F 5 17  ? 111.594 85.353  116.741 1.00 18.27 ? -18 DT  E C7    1 
ATOM   6451 C  C6    . DT  F 5 17  ? 112.618 87.561  117.187 1.00 15.06 ? -18 DT  E C6    1 
ATOM   6452 P  P     . DT  F 5 18  ? 112.379 93.721  116.791 1.00 11.48 ? -17 DT  E P     1 
ATOM   6453 O  OP1   . DT  F 5 18  ? 112.427 95.074  117.396 1.00 14.38 ? -17 DT  E OP1   1 
ATOM   6454 O  OP2   . DT  F 5 18  ? 111.360 93.435  115.759 1.00 7.20  ? -17 DT  E OP2   1 
ATOM   6455 O  "O5'" . DT  F 5 18  ? 113.826 93.369  116.215 1.00 8.75  ? -17 DT  E "O5'" 1 
ATOM   6456 C  "C5'" . DT  F 5 18  ? 114.971 93.566  117.033 1.00 11.81 ? -17 DT  E "C5'" 1 
ATOM   6457 C  "C4'" . DT  F 5 18  ? 116.230 93.073  116.346 1.00 15.65 ? -17 DT  E "C4'" 1 
ATOM   6458 O  "O4'" . DT  F 5 18  ? 116.191 91.649  116.129 1.00 11.57 ? -17 DT  E "O4'" 1 
ATOM   6459 C  "C3'" . DT  F 5 18  ? 116.517 93.710  114.994 1.00 6.14  ? -17 DT  E "C3'" 1 
ATOM   6460 O  "O3'" . DT  F 5 18  ? 117.807 94.281  115.067 1.00 13.96 ? -17 DT  E "O3'" 1 
ATOM   6461 C  "C2'" . DT  F 5 18  ? 116.414 92.537  113.990 1.00 8.29  ? -17 DT  E "C2'" 1 
ATOM   6462 C  "C1'" . DT  F 5 18  ? 116.755 91.352  114.874 1.00 14.03 ? -17 DT  E "C1'" 1 
ATOM   6463 N  N1    . DT  F 5 18  ? 116.187 90.037  114.486 1.00 9.83  ? -17 DT  E N1    1 
ATOM   6464 C  C2    . DT  F 5 18  ? 116.999 88.933  114.518 1.00 14.59 ? -17 DT  E C2    1 
ATOM   6465 O  O2    . DT  F 5 18  ? 118.189 88.996  114.734 1.00 13.43 ? -17 DT  E O2    1 
ATOM   6466 N  N3    . DT  F 5 18  ? 116.373 87.750  114.242 1.00 11.52 ? -17 DT  E N3    1 
ATOM   6467 C  C4    . DT  F 5 18  ? 115.043 87.558  113.992 1.00 7.32  ? -17 DT  E C4    1 
ATOM   6468 O  O4    . DT  F 5 18  ? 114.576 86.455  113.751 1.00 6.55  ? -17 DT  E O4    1 
ATOM   6469 C  C5    . DT  F 5 18  ? 114.239 88.743  114.011 1.00 7.17  ? -17 DT  E C5    1 
ATOM   6470 C  C7    . DT  F 5 18  ? 112.772 88.651  113.735 1.00 6.40  ? -17 DT  E C7    1 
ATOM   6471 C  C6    . DT  F 5 18  ? 114.839 89.914  114.273 1.00 7.03  ? -17 DT  E C6    1 
ATOM   6472 P  P     . DC  F 5 19  ? 118.435 95.111  113.853 1.00 4.21  ? -16 DC  E P     1 
ATOM   6473 O  OP1   . DC  F 5 19  ? 119.459 95.996  114.455 1.00 9.08  ? -16 DC  E OP1   1 
ATOM   6474 O  OP2   . DC  F 5 19  ? 117.328 95.701  113.074 1.00 7.55  ? -16 DC  E OP2   1 
ATOM   6475 O  "O5'" . DC  F 5 19  ? 119.181 94.017  112.957 1.00 2.08  ? -16 DC  E "O5'" 1 
ATOM   6476 C  "C5'" . DC  F 5 19  ? 120.383 93.393  113.433 1.00 2.67  ? -16 DC  E "C5'" 1 
ATOM   6477 C  "C4'" . DC  F 5 19  ? 120.842 92.294  112.482 1.00 11.62 ? -16 DC  E "C4'" 1 
ATOM   6478 O  "O4'" . DC  F 5 19  ? 119.938 91.155  112.537 1.00 7.63  ? -16 DC  E "O4'" 1 
ATOM   6479 C  "C3'" . DC  F 5 19  ? 120.876 92.740  111.017 1.00 3.98  ? -16 DC  E "C3'" 1 
ATOM   6480 O  "O3'" . DC  F 5 19  ? 121.983 92.206  110.323 1.00 4.48  ? -16 DC  E "O3'" 1 
ATOM   6481 C  "C2'" . DC  F 5 19  ? 119.611 92.104  110.457 1.00 9.39  ? -16 DC  E "C2'" 1 
ATOM   6482 C  "C1'" . DC  F 5 19  ? 119.636 90.792  111.213 1.00 3.91  ? -16 DC  E "C1'" 1 
ATOM   6483 N  N1    . DC  F 5 19  ? 118.379 90.008  111.133 1.00 7.77  ? -16 DC  E N1    1 
ATOM   6484 C  C2    . DC  F 5 19  ? 118.449 88.622  111.148 1.00 11.65 ? -16 DC  E C2    1 
ATOM   6485 O  O2    . DC  F 5 19  ? 119.541 88.083  111.282 1.00 10.42 ? -16 DC  E O2    1 
ATOM   6486 N  N3    . DC  F 5 19  ? 117.315 87.900  111.038 1.00 4.35  ? -16 DC  E N3    1 
ATOM   6487 C  C4    . DC  F 5 19  ? 116.154 88.513  110.898 1.00 6.89  ? -16 DC  E C4    1 
ATOM   6488 N  N4    . DC  F 5 19  ? 115.062 87.753  110.794 1.00 8.15  ? -16 DC  E N4    1 
ATOM   6489 C  C5    . DC  F 5 19  ? 116.056 89.933  110.854 1.00 10.24 ? -16 DC  E C5    1 
ATOM   6490 C  C6    . DC  F 5 19  ? 117.186 90.636  110.964 1.00 3.52  ? -16 DC  E C6    1 
ATOM   6491 P  P     . DG  F 5 20  ? 123.397 92.956  110.330 1.00 1.80  ? -15 DG  E P     1 
ATOM   6492 O  OP1   . DG  F 5 20  ? 123.924 92.911  111.712 1.00 2.32  ? -15 DG  E OP1   1 
ATOM   6493 O  OP2   . DG  F 5 20  ? 123.220 94.266  109.666 1.00 6.48  ? -15 DG  E OP2   1 
ATOM   6494 O  "O5'" . DG  F 5 20  ? 124.326 92.015  109.435 1.00 7.68  ? -15 DG  E "O5'" 1 
ATOM   6495 C  "C5'" . DG  F 5 20  ? 124.896 90.828  109.964 1.00 7.31  ? -15 DG  E "C5'" 1 
ATOM   6496 C  "C4'" . DG  F 5 20  ? 124.527 89.621  109.113 1.00 4.79  ? -15 DG  E "C4'" 1 
ATOM   6497 O  "O4'" . DG  F 5 20  ? 123.118 89.371  109.130 1.00 11.50 ? -15 DG  E "O4'" 1 
ATOM   6498 C  "C3'" . DG  F 5 20  ? 124.912 89.728  107.641 1.00 7.42  ? -15 DG  E "C3'" 1 
ATOM   6499 O  "O3'" . DG  F 5 20  ? 126.080 88.960  107.416 1.00 5.42  ? -15 DG  E "O3'" 1 
ATOM   6500 C  "C2'" . DG  F 5 20  ? 123.685 89.198  106.862 1.00 7.13  ? -15 DG  E "C2'" 1 
ATOM   6501 C  "C1'" . DG  F 5 20  ? 122.783 88.654  107.962 1.00 9.07  ? -15 DG  E "C1'" 1 
ATOM   6502 N  N9    . DG  F 5 20  ? 121.352 88.828  107.750 1.00 8.31  ? -15 DG  E N9    1 
ATOM   6503 C  C8    . DG  F 5 20  ? 120.670 90.015  107.671 1.00 4.27  ? -15 DG  E C8    1 
ATOM   6504 N  N7    . DG  F 5 20  ? 119.388 89.866  107.528 1.00 2.28  ? -15 DG  E N7    1 
ATOM   6505 C  C5    . DG  F 5 20  ? 119.207 88.493  107.513 1.00 5.32  ? -15 DG  E C5    1 
ATOM   6506 C  C6    . DG  F 5 20  ? 118.030 87.739  107.376 1.00 7.92  ? -15 DG  E C6    1 
ATOM   6507 O  O6    . DG  F 5 20  ? 116.871 88.145  107.251 1.00 3.72  ? -15 DG  E O6    1 
ATOM   6508 N  N1    . DG  F 5 20  ? 118.285 86.374  107.417 1.00 9.15  ? -15 DG  E N1    1 
ATOM   6509 C  C2    . DG  F 5 20  ? 119.525 85.819  107.557 1.00 2.28  ? -15 DG  E C2    1 
ATOM   6510 N  N2    . DG  F 5 20  ? 119.580 84.486  107.562 1.00 4.22  ? -15 DG  E N2    1 
ATOM   6511 N  N3    . DG  F 5 20  ? 120.634 86.513  107.688 1.00 9.67  ? -15 DG  E N3    1 
ATOM   6512 C  C4    . DG  F 5 20  ? 120.402 87.841  107.660 1.00 3.55  ? -15 DG  E C4    1 
ATOM   6513 P  P     . DA  F 5 21  ? 126.790 88.926  105.981 1.00 4.90  ? -14 DA  E P     1 
ATOM   6514 O  OP1   . DA  F 5 21  ? 128.194 88.518  106.183 1.00 3.75  ? -14 DA  E OP1   1 
ATOM   6515 O  OP2   . DA  F 5 21  ? 126.494 90.190  105.276 1.00 7.75  ? -14 DA  E OP2   1 
ATOM   6516 O  "O5'" . DA  F 5 21  ? 126.038 87.750  105.221 1.00 1.14  ? -14 DA  E "O5'" 1 
ATOM   6517 C  "C5'" . DA  F 5 21  ? 126.222 86.406  105.626 1.00 0.63  ? -14 DA  E "C5'" 1 
ATOM   6518 C  "C4'" . DA  F 5 21  ? 125.362 85.494  104.778 1.00 5.85  ? -14 DA  E "C4'" 1 
ATOM   6519 O  "O4'" . DA  F 5 21  ? 123.973 85.788  105.013 1.00 6.22  ? -14 DA  E "O4'" 1 
ATOM   6520 C  "C3'" . DA  F 5 21  ? 125.611 85.677  103.282 1.00 7.58  ? -14 DA  E "C3'" 1 
ATOM   6521 O  "O3'" . DA  F 5 21  ? 126.201 84.498  102.735 1.00 7.82  ? -14 DA  E "O3'" 1 
ATOM   6522 C  "C2'" . DA  F 5 21  ? 124.229 85.970  102.684 1.00 0.11  ? -14 DA  E "C2'" 1 
ATOM   6523 C  "C1'" . DA  F 5 21  ? 123.253 85.671  103.822 1.00 0.85  ? -14 DA  E "C1'" 1 
ATOM   6524 N  N9    . DA  F 5 21  ? 122.106 86.577  103.883 1.00 4.67  ? -14 DA  E N9    1 
ATOM   6525 C  C8    . DA  F 5 21  ? 122.130 87.938  103.810 1.00 7.99  ? -14 DA  E C8    1 
ATOM   6526 N  N7    . DA  F 5 21  ? 120.953 88.491  103.898 1.00 8.00  ? -14 DA  E N7    1 
ATOM   6527 C  C5    . DA  F 5 21  ? 120.089 87.419  104.053 1.00 4.07  ? -14 DA  E C5    1 
ATOM   6528 C  C6    . DA  F 5 21  ? 118.692 87.341  104.202 1.00 7.66  ? -14 DA  E C6    1 
ATOM   6529 N  N6    . DA  F 5 21  ? 117.901 88.405  104.217 1.00 4.92  ? -14 DA  E N6    1 
ATOM   6530 N  N1    . DA  F 5 21  ? 118.142 86.122  104.329 1.00 2.40  ? -14 DA  E N1    1 
ATOM   6531 C  C2    . DA  F 5 21  ? 118.942 85.051  104.304 1.00 3.36  ? -14 DA  E C2    1 
ATOM   6532 N  N3    . DA  F 5 21  ? 120.264 85.002  104.168 1.00 4.55  ? -14 DA  E N3    1 
ATOM   6533 C  C4    . DA  F 5 21  ? 120.781 86.234  104.051 1.00 4.00  ? -14 DA  E C4    1 
ATOM   6534 P  P     . DT  F 5 22  ? 127.227 84.603  101.505 1.00 16.27 ? -13 DT  E P     1 
ATOM   6535 O  OP1   . DT  F 5 22  ? 127.892 83.298  101.393 1.00 16.20 ? -13 DT  E OP1   1 
ATOM   6536 O  OP2   . DT  F 5 22  ? 128.034 85.819  101.685 1.00 10.96 ? -13 DT  E OP2   1 
ATOM   6537 O  "O5'" . DT  F 5 22  ? 126.334 84.844  100.218 1.00 16.64 ? -13 DT  E "O5'" 1 
ATOM   6538 C  "C5'" . DT  F 5 22  ? 125.601 83.811  99.622  1.00 8.75  ? -13 DT  E "C5'" 1 
ATOM   6539 C  "C4'" . DT  F 5 22  ? 124.709 84.406  98.557  1.00 8.28  ? -13 DT  E "C4'" 1 
ATOM   6540 O  "O4'" . DT  F 5 22  ? 123.772 85.290  99.158  1.00 8.36  ? -13 DT  E "O4'" 1 
ATOM   6541 C  "C3'" . DT  F 5 22  ? 125.448 85.244  97.535  1.00 12.07 ? -13 DT  E "C3'" 1 
ATOM   6542 O  "O3'" . DT  F 5 22  ? 125.759 84.437  96.411  1.00 7.23  ? -13 DT  E "O3'" 1 
ATOM   6543 C  "C2'" . DT  F 5 22  ? 124.491 86.407  97.208  1.00 16.49 ? -13 DT  E "C2'" 1 
ATOM   6544 C  "C1'" . DT  F 5 22  ? 123.380 86.277  98.243  1.00 15.28 ? -13 DT  E "C1'" 1 
ATOM   6545 N  N1    . DT  F 5 22  ? 123.098 87.488  99.033  1.00 7.16  ? -13 DT  E N1    1 
ATOM   6546 C  C2    . DT  F 5 22  ? 121.846 88.028  98.989  1.00 8.77  ? -13 DT  E C2    1 
ATOM   6547 O  O2    . DT  F 5 22  ? 120.955 87.571  98.319  1.00 10.33 ? -13 DT  E O2    1 
ATOM   6548 N  N3    . DT  F 5 22  ? 121.658 89.110  99.783  1.00 8.32  ? -13 DT  E N3    1 
ATOM   6549 C  C4    . DT  F 5 22  ? 122.585 89.717  100.592 1.00 15.11 ? -13 DT  E C4    1 
ATOM   6550 O  O4    . DT  F 5 22  ? 122.315 90.705  101.265 1.00 10.46 ? -13 DT  E O4    1 
ATOM   6551 C  C5    . DT  F 5 22  ? 123.892 89.104  100.595 1.00 16.41 ? -13 DT  E C5    1 
ATOM   6552 C  C7    . DT  F 5 22  ? 124.993 89.669  101.439 1.00 12.83 ? -13 DT  E C7    1 
ATOM   6553 C  C6    . DT  F 5 22  ? 124.081 88.029  99.823  1.00 15.80 ? -13 DT  E C6    1 
ATOM   6554 P  P     . DG  F 5 23  ? 126.582 85.035  95.177  1.00 20.89 ? -12 DG  E P     1 
ATOM   6555 O  OP1   . DG  F 5 23  ? 127.063 83.872  94.415  1.00 21.50 ? -12 DG  E OP1   1 
ATOM   6556 O  OP2   . DG  F 5 23  ? 127.514 86.045  95.691  1.00 17.05 ? -12 DG  E OP2   1 
ATOM   6557 O  "O5'" . DG  F 5 23  ? 125.493 85.788  94.279  1.00 17.91 ? -12 DG  E "O5'" 1 
ATOM   6558 C  "C5'" . DG  F 5 23  ? 124.528 85.034  93.555  1.00 20.43 ? -12 DG  E "C5'" 1 
ATOM   6559 C  "C4'" . DG  F 5 23  ? 123.496 85.941  92.919  1.00 15.30 ? -12 DG  E "C4'" 1 
ATOM   6560 O  "O4'" . DG  F 5 23  ? 122.663 86.560  93.934  1.00 17.35 ? -12 DG  E "O4'" 1 
ATOM   6561 C  "C3'" . DG  F 5 23  ? 124.101 87.079  92.140  1.00 18.44 ? -12 DG  E "C3'" 1 
ATOM   6562 O  "O3'" . DG  F 5 23  ? 124.345 86.716  90.794  1.00 12.60 ? -12 DG  E "O3'" 1 
ATOM   6563 C  "C2'" . DG  F 5 23  ? 123.030 88.169  92.260  1.00 18.38 ? -12 DG  E "C2'" 1 
ATOM   6564 C  "C1'" . DG  F 5 23  ? 122.510 87.941  93.668  1.00 16.78 ? -12 DG  E "C1'" 1 
ATOM   6565 N  N9    . DG  F 5 23  ? 123.202 88.733  94.678  1.00 20.52 ? -12 DG  E N9    1 
ATOM   6566 C  C8    . DG  F 5 23  ? 124.555 88.865  94.840  1.00 15.60 ? -12 DG  E C8    1 
ATOM   6567 N  N7    . DG  F 5 23  ? 124.888 89.670  95.805  1.00 21.38 ? -12 DG  E N7    1 
ATOM   6568 C  C5    . DG  F 5 23  ? 123.678 90.114  96.308  1.00 18.22 ? -12 DG  E C5    1 
ATOM   6569 C  C6    . DG  F 5 23  ? 123.406 91.012  97.366  1.00 14.29 ? -12 DG  E C6    1 
ATOM   6570 O  O6    . DG  F 5 23  ? 124.211 91.607  98.093  1.00 20.33 ? -12 DG  E O6    1 
ATOM   6571 N  N1    . DG  F 5 23  ? 122.040 91.185  97.556  1.00 18.57 ? -12 DG  E N1    1 
ATOM   6572 C  C2    . DG  F 5 23  ? 121.069 90.577  96.813  1.00 12.99 ? -12 DG  E C2    1 
ATOM   6573 N  N2    . DG  F 5 23  ? 119.810 90.863  97.143  1.00 16.65 ? -12 DG  E N2    1 
ATOM   6574 N  N3    . DG  F 5 23  ? 121.309 89.737  95.820  1.00 19.24 ? -12 DG  E N3    1 
ATOM   6575 C  C4    . DG  F 5 23  ? 122.630 89.550  95.625  1.00 21.63 ? -12 DG  E C4    1 
ATOM   6576 P  P     . DC  F 5 24  ? 125.074 87.767  89.820  1.00 28.62 ? -11 DC  E P     1 
ATOM   6577 O  OP1   . DC  F 5 24  ? 125.402 86.989  88.613  1.00 38.38 ? -11 DC  E OP1   1 
ATOM   6578 O  OP2   . DC  F 5 24  ? 126.134 88.492  90.550  1.00 32.38 ? -11 DC  E OP2   1 
ATOM   6579 O  "O5'" . DC  F 5 24  ? 123.954 88.825  89.406  1.00 38.35 ? -11 DC  E "O5'" 1 
ATOM   6580 C  "C5'" . DC  F 5 24  ? 122.884 88.433  88.595  1.00 34.66 ? -11 DC  E "C5'" 1 
ATOM   6581 C  "C4'" . DC  F 5 24  ? 121.891 89.564  88.420  1.00 36.91 ? -11 DC  E "C4'" 1 
ATOM   6582 O  "O4'" . DC  F 5 24  ? 121.348 89.977  89.699  1.00 34.36 ? -11 DC  E "O4'" 1 
ATOM   6583 C  "C3'" . DC  F 5 24  ? 122.467 90.812  87.773  1.00 34.90 ? -11 DC  E "C3'" 1 
ATOM   6584 O  "O3'" . DC  F 5 24  ? 122.364 90.714  86.348  1.00 31.47 ? -11 DC  E "O3'" 1 
ATOM   6585 C  "C2'" . DC  F 5 24  ? 121.587 91.902  88.363  1.00 34.49 ? -11 DC  E "C2'" 1 
ATOM   6586 C  "C1'" . DC  F 5 24  ? 121.351 91.382  89.785  1.00 36.12 ? -11 DC  E "C1'" 1 
ATOM   6587 N  N1    . DC  F 5 24  ? 122.358 91.797  90.828  1.00 37.20 ? -11 DC  E N1    1 
ATOM   6588 C  C2    . DC  F 5 24  ? 122.035 91.654  92.185  1.00 36.17 ? -11 DC  E C2    1 
ATOM   6589 O  O2    . DC  F 5 24  ? 120.933 91.206  92.500  1.00 35.60 ? -11 DC  E O2    1 
ATOM   6590 N  N3    . DC  F 5 24  ? 122.942 92.014  93.117  1.00 37.26 ? -11 DC  E N3    1 
ATOM   6591 C  C4    . DC  F 5 24  ? 124.126 92.495  92.746  1.00 31.84 ? -11 DC  E C4    1 
ATOM   6592 N  N4    . DC  F 5 24  ? 124.987 92.835  93.703  1.00 35.33 ? -11 DC  E N4    1 
ATOM   6593 C  C5    . DC  F 5 24  ? 124.481 92.644  91.374  1.00 33.13 ? -11 DC  E C5    1 
ATOM   6594 C  C6    . DC  F 5 24  ? 123.575 92.295  90.458  1.00 32.44 ? -11 DC  E C6    1 
ATOM   6595 P  P     . DA  F 5 25  ? 123.061 91.793  85.375  1.00 52.42 ? -10 DA  E P     1 
ATOM   6596 O  OP1   . DA  F 5 25  ? 123.106 91.183  84.029  1.00 52.32 ? -10 DA  E OP1   1 
ATOM   6597 O  OP2   . DA  F 5 25  ? 124.327 92.222  85.997  1.00 51.48 ? -10 DA  E OP2   1 
ATOM   6598 O  "O5'" . DA  F 5 25  ? 122.066 93.049  85.360  1.00 54.53 ? -10 DA  E "O5'" 1 
ATOM   6599 C  "C5'" . DA  F 5 25  ? 120.736 92.880  84.868  1.00 52.61 ? -10 DA  E "C5'" 1 
ATOM   6600 C  "C4'" . DA  F 5 25  ? 119.792 93.948  85.408  1.00 58.05 ? -10 DA  E "C4'" 1 
ATOM   6601 O  "O4'" . DA  F 5 25  ? 119.950 94.075  86.841  1.00 55.09 ? -10 DA  E "O4'" 1 
ATOM   6602 C  "C3'" . DA  F 5 25  ? 119.974 95.348  84.835  1.00 50.30 ? -10 DA  E "C3'" 1 
ATOM   6603 O  "O3'" . DA  F 5 25  ? 118.679 95.964  84.743  1.00 52.58 ? -10 DA  E "O3'" 1 
ATOM   6604 C  "C2'" . DA  F 5 25  ? 120.812 96.029  85.913  1.00 51.74 ? -10 DA  E "C2'" 1 
ATOM   6605 C  "C1'" . DA  F 5 25  ? 120.198 95.420  87.161  1.00 56.29 ? -10 DA  E "C1'" 1 
ATOM   6606 N  N9    . DA  F 5 25  ? 121.029 95.455  88.360  1.00 57.11 ? -10 DA  E N9    1 
ATOM   6607 C  C8    . DA  F 5 25  ? 122.385 95.290  88.439  1.00 57.35 ? -10 DA  E C8    1 
ATOM   6608 N  N7    . DA  F 5 25  ? 122.854 95.365  89.664  1.00 54.94 ? -10 DA  E N7    1 
ATOM   6609 C  C5    . DA  F 5 25  ? 121.730 95.612  90.436  1.00 51.01 ? -10 DA  E C5    1 
ATOM   6610 C  C6    . DA  F 5 25  ? 121.549 95.805  91.819  1.00 50.83 ? -10 DA  E C6    1 
ATOM   6611 N  N6    . DA  F 5 25  ? 122.550 95.769  92.704  1.00 56.86 ? -10 DA  E N6    1 
ATOM   6612 N  N1    . DA  F 5 25  ? 120.291 96.037  92.263  1.00 53.59 ? -10 DA  E N1    1 
ATOM   6613 C  C2    . DA  F 5 25  ? 119.290 96.071  91.381  1.00 56.33 ? -10 DA  E C2    1 
ATOM   6614 N  N3    . DA  F 5 25  ? 119.337 95.903  90.061  1.00 54.03 ? -10 DA  E N3    1 
ATOM   6615 C  C4    . DA  F 5 25  ? 120.599 95.671  89.649  1.00 55.64 ? -10 DA  E C4    1 
ATOM   6616 P  P     . DA  F 5 26  ? 118.236 96.880  83.495  1.00 52.10 ? -9  DA  E P     1 
ATOM   6617 O  OP1   . DA  F 5 26  ? 119.189 98.005  83.404  1.00 54.62 ? -9  DA  E OP1   1 
ATOM   6618 O  OP2   . DA  F 5 26  ? 116.799 97.185  83.670  1.00 52.60 ? -9  DA  E OP2   1 
ATOM   6619 O  "O5'" . DA  F 5 26  ? 118.418 95.960  82.188  1.00 51.57 ? -9  DA  E "O5'" 1 
ATOM   6620 C  "C5'" . DA  F 5 26  ? 117.863 94.645  82.131  1.00 50.34 ? -9  DA  E "C5'" 1 
ATOM   6621 C  "C4'" . DA  F 5 26  ? 117.980 94.054  80.728  1.00 47.59 ? -9  DA  E "C4'" 1 
ATOM   6622 O  "O4'" . DA  F 5 26  ? 117.729 92.628  80.803  1.00 50.69 ? -9  DA  E "O4'" 1 
ATOM   6623 C  "C3'" . DA  F 5 26  ? 116.940 94.580  79.736  1.00 47.71 ? -9  DA  E "C3'" 1 
ATOM   6624 O  "O3'" . DA  F 5 26  ? 117.367 94.343  78.397  1.00 56.74 ? -9  DA  E "O3'" 1 
ATOM   6625 C  "C2'" . DA  F 5 26  ? 115.772 93.668  80.054  1.00 48.73 ? -9  DA  E "C2'" 1 
ATOM   6626 C  "C1'" . DA  F 5 26  ? 116.532 92.354  80.104  1.00 55.03 ? -9  DA  E "C1'" 1 
ATOM   6627 N  N9    . DA  F 5 26  ? 115.856 91.244  80.754  1.00 55.66 ? -9  DA  E N9    1 
ATOM   6628 C  C8    . DA  F 5 26  ? 115.724 91.028  82.085  1.00 53.80 ? -9  DA  E C8    1 
ATOM   6629 N  N7    . DA  F 5 26  ? 115.086 89.925  82.379  1.00 52.61 ? -9  DA  E N7    1 
ATOM   6630 C  C5    . DA  F 5 26  ? 114.762 89.396  81.150  1.00 48.52 ? -9  DA  E C5    1 
ATOM   6631 C  C6    . DA  F 5 26  ? 114.073 88.233  80.769  1.00 51.58 ? -9  DA  E C6    1 
ATOM   6632 N  N6    . DA  F 5 26  ? 113.556 87.362  81.640  1.00 50.36 ? -9  DA  E N6    1 
ATOM   6633 N  N1    . DA  F 5 26  ? 113.925 88.001  79.454  1.00 49.16 ? -9  DA  E N1    1 
ATOM   6634 C  C2    . DA  F 5 26  ? 114.437 88.870  78.586  1.00 52.84 ? -9  DA  E C2    1 
ATOM   6635 N  N3    . DA  F 5 26  ? 115.103 89.994  78.824  1.00 50.04 ? -9  DA  E N3    1 
ATOM   6636 C  C4    . DA  F 5 26  ? 115.228 90.200  80.139  1.00 56.08 ? -9  DA  E C4    1 
ATOM   6637 P  P     . DG  F 5 27  ? 116.655 95.079  77.158  1.00 50.19 ? -8  DG  E P     1 
ATOM   6638 O  OP1   . DG  F 5 27  ? 117.339 94.651  75.922  1.00 42.21 ? -8  DG  E OP1   1 
ATOM   6639 O  OP2   . DG  F 5 27  ? 116.597 96.519  77.492  1.00 43.67 ? -8  DG  E OP2   1 
ATOM   6640 O  "O5'" . DG  F 5 27  ? 115.162 94.496  77.112  1.00 43.03 ? -8  DG  E "O5'" 1 
ATOM   6641 C  "C5'" . DG  F 5 27  ? 114.882 93.202  76.564  1.00 46.09 ? -8  DG  E "C5'" 1 
ATOM   6642 C  "C4'" . DG  F 5 27  ? 113.465 92.761  76.922  1.00 48.38 ? -8  DG  E "C4'" 1 
ATOM   6643 O  "O4'" . DG  F 5 27  ? 113.377 92.233  78.255  1.00 43.18 ? -8  DG  E "O4'" 1 
ATOM   6644 C  "C3'" . DG  F 5 27  ? 112.407 93.855  76.818  1.00 43.58 ? -8  DG  E "C3'" 1 
ATOM   6645 O  "O3'" . DG  F 5 27  ? 111.601 93.588  75.684  1.00 49.61 ? -8  DG  E "O3'" 1 
ATOM   6646 C  "C2'" . DG  F 5 27  ? 111.639 93.792  78.166  1.00 45.26 ? -8  DG  E "C2'" 1 
ATOM   6647 C  "C1'" . DG  F 5 27  ? 112.068 92.440  78.723  1.00 47.26 ? -8  DG  E "C1'" 1 
ATOM   6648 N  N9    . DG  F 5 27  ? 112.138 92.334  80.175  1.00 43.43 ? -8  DG  E N9    1 
ATOM   6649 C  C8    . DG  F 5 27  ? 112.716 93.220  81.042  1.00 42.12 ? -8  DG  E C8    1 
ATOM   6650 N  N7    . DG  F 5 27  ? 112.672 92.832  82.286  1.00 46.26 ? -8  DG  E N7    1 
ATOM   6651 C  C5    . DG  F 5 27  ? 112.001 91.618  82.245  1.00 45.87 ? -8  DG  E C5    1 
ATOM   6652 C  C6    . DG  F 5 27  ? 111.630 90.733  83.296  1.00 42.62 ? -8  DG  E C6    1 
ATOM   6653 O  O6    . DG  F 5 27  ? 111.838 90.845  84.514  1.00 47.32 ? -8  DG  E O6    1 
ATOM   6654 N  N1    . DG  F 5 27  ? 110.952 89.621  82.814  1.00 46.54 ? -8  DG  E N1    1 
ATOM   6655 C  C2    . DG  F 5 27  ? 110.666 89.388  81.495  1.00 47.64 ? -8  DG  E C2    1 
ATOM   6656 N  N2    . DG  F 5 27  ? 110.006 88.256  81.227  1.00 42.54 ? -8  DG  E N2    1 
ATOM   6657 N  N3    . DG  F 5 27  ? 111.007 90.200  80.506  1.00 48.61 ? -8  DG  E N3    1 
ATOM   6658 C  C4    . DG  F 5 27  ? 111.664 91.297  80.954  1.00 43.32 ? -8  DG  E C4    1 
ATOM   6659 P  P     . DC  F 5 28  ? 110.493 94.630  75.187  1.00 43.18 ? -7  DC  E P     1 
ATOM   6660 O  OP1   . DC  F 5 28  ? 110.228 94.330  73.763  1.00 38.21 ? -7  DC  E OP1   1 
ATOM   6661 O  OP2   . DC  F 5 28  ? 110.947 95.980  75.587  1.00 45.84 ? -7  DC  E OP2   1 
ATOM   6662 O  "O5'" . DC  F 5 28  ? 109.194 94.233  76.017  1.00 41.23 ? -7  DC  E "O5'" 1 
ATOM   6663 C  "C5'" . DC  F 5 28  ? 108.572 92.977  75.772  1.00 46.72 ? -7  DC  E "C5'" 1 
ATOM   6664 C  "C4'" . DC  F 5 28  ? 107.655 92.570  76.913  1.00 46.43 ? -7  DC  E "C4'" 1 
ATOM   6665 O  "O4'" . DC  F 5 28  ? 108.373 92.293  78.127  1.00 43.37 ? -7  DC  E "O4'" 1 
ATOM   6666 C  "C3'" . DC  F 5 28  ? 106.639 93.604  77.335  1.00 46.65 ? -7  DC  E "C3'" 1 
ATOM   6667 O  "O3'" . DC  F 5 28  ? 105.509 93.582  76.482  1.00 47.48 ? -7  DC  E "O3'" 1 
ATOM   6668 C  "C2'" . DC  F 5 28  ? 106.288 93.173  78.764  1.00 46.25 ? -7  DC  E "C2'" 1 
ATOM   6669 C  "C1'" . DC  F 5 28  ? 107.389 92.188  79.137  1.00 46.53 ? -7  DC  E "C1'" 1 
ATOM   6670 N  N1    . DC  F 5 28  ? 107.989 92.435  80.470  1.00 38.97 ? -7  DC  E N1    1 
ATOM   6671 C  C2    . DC  F 5 28  ? 107.711 91.551  81.517  1.00 44.50 ? -7  DC  E C2    1 
ATOM   6672 O  O2    . DC  F 5 28  ? 106.984 90.580  81.306  1.00 45.02 ? -7  DC  E O2    1 
ATOM   6673 N  N3    . DC  F 5 28  ? 108.266 91.771  82.727  1.00 44.09 ? -7  DC  E N3    1 
ATOM   6674 C  C4    . DC  F 5 28  ? 109.047 92.828  82.915  1.00 45.98 ? -7  DC  E C4    1 
ATOM   6675 N  N4    . DC  F 5 28  ? 109.570 93.003  84.130  1.00 38.33 ? -7  DC  E N4    1 
ATOM   6676 C  C5    . DC  F 5 28  ? 109.331 93.753  81.864  1.00 45.69 ? -7  DC  E C5    1 
ATOM   6677 C  C6    . DC  F 5 28  ? 108.779 93.520  80.669  1.00 45.30 ? -7  DC  E C6    1 
ATOM   6678 P  P     . DC  F 5 29  ? 104.421 94.764  76.570  1.00 56.27 ? -6  DC  E P     1 
ATOM   6679 O  OP1   . DC  F 5 29  ? 103.522 94.643  75.401  1.00 56.25 ? -6  DC  E OP1   1 
ATOM   6680 O  OP2   . DC  F 5 29  ? 105.200 96.003  76.788  1.00 60.00 ? -6  DC  E OP2   1 
ATOM   6681 O  "O5'" . DC  F 5 29  ? 103.576 94.453  77.899  1.00 57.13 ? -6  DC  E "O5'" 1 
ATOM   6682 C  "C5'" . DC  F 5 29  ? 103.723 95.238  79.093  1.00 61.64 ? -6  DC  E "C5'" 1 
ATOM   6683 C  "C4'" . DC  F 5 29  ? 103.273 94.426  80.306  1.00 58.14 ? -6  DC  E "C4'" 1 
ATOM   6684 O  "O4'" . DC  F 5 29  ? 104.394 93.827  81.003  1.00 61.51 ? -6  DC  E "O4'" 1 
ATOM   6685 C  "C3'" . DC  F 5 29  ? 102.619 95.275  81.383  1.00 63.58 ? -6  DC  E "C3'" 1 
ATOM   6686 O  "O3'" . DC  F 5 29  ? 101.265 95.647  81.047  1.00 56.68 ? -6  DC  E "O3'" 1 
ATOM   6687 C  "C2'" . DC  F 5 29  ? 102.749 94.414  82.639  1.00 55.11 ? -6  DC  E "C2'" 1 
ATOM   6688 C  "C1'" . DC  F 5 29  ? 104.015 93.585  82.356  1.00 62.69 ? -6  DC  E "C1'" 1 
ATOM   6689 N  N1    . DC  F 5 29  ? 105.094 94.019  83.252  1.00 59.09 ? -6  DC  E N1    1 
ATOM   6690 C  C2    . DC  F 5 29  ? 105.271 93.368  84.471  1.00 63.43 ? -6  DC  E C2    1 
ATOM   6691 O  O2    . DC  F 5 29  ? 104.592 92.372  84.720  1.00 60.04 ? -6  DC  E O2    1 
ATOM   6692 N  N3    . DC  F 5 29  ? 106.223 93.816  85.324  1.00 63.62 ? -6  DC  E N3    1 
ATOM   6693 C  C4    . DC  F 5 29  ? 106.934 94.905  85.015  1.00 59.14 ? -6  DC  E C4    1 
ATOM   6694 N  N4    . DC  F 5 29  ? 107.858 95.318  85.887  1.00 58.94 ? -6  DC  E N4    1 
ATOM   6695 C  C5    . DC  F 5 29  ? 106.733 95.610  83.794  1.00 55.03 ? -6  DC  E C5    1 
ATOM   6696 C  C6    . DC  F 5 29  ? 105.795 95.150  82.962  1.00 57.23 ? -6  DC  E C6    1 
ATOM   6697 P  P     . DC  F 5 30  ? 100.029 94.628  81.231  1.00 59.38 ? -5  DC  E P     1 
ATOM   6698 O  OP1   . DC  F 5 30  ? 99.087  94.951  80.135  1.00 66.57 ? -5  DC  E OP1   1 
ATOM   6699 O  OP2   . DC  F 5 30  ? 99.556  94.694  82.634  1.00 60.72 ? -5  DC  E OP2   1 
ATOM   6700 O  "O5'" . DC  F 5 30  ? 100.636 93.176  80.934  1.00 59.42 ? -5  DC  E "O5'" 1 
ATOM   6701 C  "C5'" . DC  F 5 30  ? 99.868  92.217  80.258  1.00 62.78 ? -5  DC  E "C5'" 1 
ATOM   6702 C  "C4'" . DC  F 5 30  ? 100.674 90.960  79.976  1.00 67.74 ? -5  DC  E "C4'" 1 
ATOM   6703 O  "O4'" . DC  F 5 30  ? 101.593 91.139  78.880  1.00 66.04 ? -5  DC  E "O4'" 1 
ATOM   6704 C  "C3'" . DC  F 5 30  ? 101.513 90.403  81.140  1.00 66.03 ? -5  DC  E "C3'" 1 
ATOM   6705 O  "O3'" . DC  F 5 30  ? 101.011 89.133  81.531  1.00 61.00 ? -5  DC  E "O3'" 1 
ATOM   6706 C  "C2'" . DC  F 5 30  ? 102.890 90.190  80.456  1.00 63.53 ? -5  DC  E "C2'" 1 
ATOM   6707 C  "C1'" . DC  F 5 30  ? 102.448 90.064  78.999  1.00 64.93 ? -5  DC  E "C1'" 1 
ATOM   6708 N  N1    . DC  F 5 30  ? 103.521 90.111  77.948  1.00 69.01 ? -5  DC  E N1    1 
ATOM   6709 C  C2    . DC  F 5 30  ? 103.161 90.177  76.589  1.00 61.15 ? -5  DC  E C2    1 
ATOM   6710 O  O2    . DC  F 5 30  ? 101.978 90.307  76.283  1.00 61.59 ? -5  DC  E O2    1 
ATOM   6711 N  N3    . DC  F 5 30  ? 104.127 90.170  75.648  1.00 61.74 ? -5  DC  E N3    1 
ATOM   6712 C  C4    . DC  F 5 30  ? 105.403 90.038  76.003  1.00 66.62 ? -5  DC  E C4    1 
ATOM   6713 N  N4    . DC  F 5 30  ? 106.325 90.024  75.032  1.00 63.69 ? -5  DC  E N4    1 
ATOM   6714 C  C5    . DC  F 5 30  ? 105.790 89.900  77.371  1.00 59.69 ? -5  DC  E C5    1 
ATOM   6715 C  C6    . DC  F 5 30  ? 104.824 89.934  78.301  1.00 64.20 ? -5  DC  E C6    1 
ATOM   6716 P  P     . DC  F 5 31  ? 99.583  88.920  82.238  1.00 2.09  ? -4  DC  E P     1 
ATOM   6717 O  OP1   . DC  F 5 31  ? 98.633  90.015  81.971  1.00 7.96  ? -4  DC  E OP1   1 
ATOM   6718 O  OP2   . DC  F 5 31  ? 99.802  88.529  83.633  1.00 2.94  ? -4  DC  E OP2   1 
ATOM   6719 O  "O5'" . DC  F 5 31  ? 99.065  87.619  81.499  1.00 0.25  ? -4  DC  E "O5'" 1 
ATOM   6720 C  "C5'" . DC  F 5 31  ? 98.899  87.609  80.115  1.00 5.90  ? -4  DC  E "C5'" 1 
ATOM   6721 C  "C4'" . DC  F 5 31  ? 97.909  86.542  79.723  1.00 8.41  ? -4  DC  E "C4'" 1 
ATOM   6722 O  "O4'" . DC  F 5 31  ? 98.129  85.369  80.522  1.00 3.78  ? -4  DC  E "O4'" 1 
ATOM   6723 C  "C3'" . DC  F 5 31  ? 96.481  86.959  79.976  1.00 7.47  ? -4  DC  E "C3'" 1 
ATOM   6724 O  "O3'" . DC  F 5 31  ? 95.921  87.448  78.774  1.00 5.08  ? -4  DC  E "O3'" 1 
ATOM   6725 C  "C2'" . DC  F 5 31  ? 95.787  85.682  80.458  1.00 5.38  ? -4  DC  E "C2'" 1 
ATOM   6726 C  "C1'" . DC  F 5 31  ? 96.919  84.732  80.829  1.00 9.56  ? -4  DC  E "C1'" 1 
ATOM   6727 N  N1    . DC  F 5 31  ? 96.940  84.317  82.266  1.00 8.01  ? -4  DC  E N1    1 
ATOM   6728 C  C2    . DC  F 5 31  ? 96.451  83.070  82.619  1.00 0.29  ? -4  DC  E C2    1 
ATOM   6729 O  O2    . DC  F 5 31  ? 96.067  82.322  81.742  1.00 7.06  ? -4  DC  E O2    1 
ATOM   6730 N  N3    . DC  F 5 31  ? 96.473  82.689  83.907  1.00 4.62  ? -4  DC  E N3    1 
ATOM   6731 C  C4    . DC  F 5 31  ? 96.894  83.512  84.827  1.00 9.45  ? -4  DC  E C4    1 
ATOM   6732 N  N4    . DC  F 5 31  ? 96.880  83.086  86.086  1.00 2.18  ? -4  DC  E N4    1 
ATOM   6733 C  C5    . DC  F 5 31  ? 97.369  84.812  84.507  1.00 2.64  ? -4  DC  E C5    1 
ATOM   6734 C  C6    . DC  F 5 31  ? 97.364  85.175  83.224  1.00 0.78  ? -4  DC  E C6    1 
ATOM   6735 P  P     . DT  F 5 32  ? 94.444  88.060  78.737  1.00 4.26  ? -3  DT  E P     1 
ATOM   6736 O  OP1   . DT  F 5 32  ? 94.294  88.766  77.462  1.00 1.06  ? -3  DT  E OP1   1 
ATOM   6737 O  OP2   . DT  F 5 32  ? 94.254  88.810  79.988  1.00 6.31  ? -3  DT  E OP2   1 
ATOM   6738 O  "O5'" . DT  F 5 32  ? 93.480  86.792  78.669  1.00 8.00  ? -3  DT  E "O5'" 1 
ATOM   6739 C  "C5'" . DT  F 5 32  ? 93.558  85.904  77.576  1.00 6.94  ? -3  DT  E "C5'" 1 
ATOM   6740 C  "C4'" . DT  F 5 32  ? 92.692  84.672  77.796  1.00 7.63  ? -3  DT  E "C4'" 1 
ATOM   6741 O  "O4'" . DT  F 5 32  ? 93.089  83.962  78.993  1.00 3.39  ? -3  DT  E "O4'" 1 
ATOM   6742 C  "C3'" . DT  F 5 32  ? 91.209  84.963  77.929  1.00 8.43  ? -3  DT  E "C3'" 1 
ATOM   6743 O  "O3'" . DT  F 5 32  ? 90.459  84.005  77.162  1.00 4.26  ? -3  DT  E "O3'" 1 
ATOM   6744 C  "C2'" . DT  F 5 32  ? 90.949  84.838  79.421  1.00 8.21  ? -3  DT  E "C2'" 1 
ATOM   6745 C  "C1'" . DT  F 5 32  ? 91.987  83.817  79.850  1.00 6.23  ? -3  DT  E "C1'" 1 
ATOM   6746 N  N1    . DT  F 5 32  ? 92.419  83.961  81.264  1.00 1.40  ? -3  DT  E N1    1 
ATOM   6747 C  C2    . DT  F 5 32  ? 92.433  82.871  82.073  1.00 0.75  ? -3  DT  E C2    1 
ATOM   6748 O  O2    . DT  F 5 32  ? 92.065  81.775  81.717  1.00 0.15  ? -3  DT  E O2    1 
ATOM   6749 N  N3    . DT  F 5 32  ? 92.825  83.118  83.350  1.00 0.64  ? -3  DT  E N3    1 
ATOM   6750 C  C4    . DT  F 5 32  ? 93.243  84.316  83.871  1.00 4.56  ? -3  DT  E C4    1 
ATOM   6751 O  O4    . DT  F 5 32  ? 93.590  84.440  85.030  1.00 1.10  ? -3  DT  E O4    1 
ATOM   6752 C  C5    . DT  F 5 32  ? 93.237  85.409  82.966  1.00 0.25  ? -3  DT  E C5    1 
ATOM   6753 C  C7    . DT  F 5 32  ? 93.671  86.761  83.428  1.00 7.52  ? -3  DT  E C7    1 
ATOM   6754 C  C6    . DT  F 5 32  ? 92.819  85.188  81.722  1.00 3.92  ? -3  DT  E C6    1 
ATOM   6755 P  P     . DA  F 5 33  ? 88.891  84.211  76.887  1.00 7.44  ? -2  DA  E P     1 
ATOM   6756 O  OP1   . DA  F 5 33  ? 88.574  83.438  75.678  1.00 4.47  ? -2  DA  E OP1   1 
ATOM   6757 O  OP2   . DA  F 5 33  ? 88.636  85.666  76.889  1.00 4.49  ? -2  DA  E OP2   1 
ATOM   6758 O  "O5'" . DA  F 5 33  ? 88.126  83.526  78.119  1.00 4.75  ? -2  DA  E "O5'" 1 
ATOM   6759 C  "C5'" . DA  F 5 33  ? 87.992  82.114  78.151  1.00 4.71  ? -2  DA  E "C5'" 1 
ATOM   6760 C  "C4'" . DA  F 5 33  ? 87.694  81.574  79.543  1.00 8.00  ? -2  DA  E "C4'" 1 
ATOM   6761 O  "O4'" . DA  F 5 33  ? 88.663  82.023  80.487  1.00 3.99  ? -2  DA  E "O4'" 1 
ATOM   6762 C  "C3'" . DA  F 5 33  ? 86.382  82.012  80.168  1.00 9.02  ? -2  DA  E "C3'" 1 
ATOM   6763 O  "O3'" . DA  F 5 33  ? 85.313  81.191  79.771  1.00 0.34  ? -2  DA  E "O3'" 1 
ATOM   6764 C  "C2'" . DA  F 5 33  ? 86.642  81.870  81.669  1.00 7.71  ? -2  DA  E "C2'" 1 
ATOM   6765 C  "C1'" . DA  F 5 33  ? 88.147  81.706  81.754  1.00 1.23  ? -2  DA  E "C1'" 1 
ATOM   6766 N  N9    . DA  F 5 33  ? 88.775  82.541  82.760  1.00 6.15  ? -2  DA  E N9    1 
ATOM   6767 C  C8    . DA  F 5 33  ? 89.171  83.830  82.632  1.00 0.07  ? -2  DA  E C8    1 
ATOM   6768 N  N7    . DA  F 5 33  ? 89.691  84.327  83.716  1.00 5.36  ? -2  DA  E N7    1 
ATOM   6769 C  C5    . DA  F 5 33  ? 89.613  83.295  84.622  1.00 -0.00 ? -2  DA  E C5    1 
ATOM   6770 C  C6    . DA  F 5 33  ? 89.985  83.185  85.962  1.00 9.48  ? -2  DA  E C6    1 
ATOM   6771 N  N6    . DA  F 5 33  ? 90.565  84.163  86.647  1.00 9.02  ? -2  DA  E N6    1 
ATOM   6772 N  N1    . DA  F 5 33  ? 89.750  82.026  86.576  1.00 7.93  ? -2  DA  E N1    1 
ATOM   6773 C  C2    . DA  F 5 33  ? 89.184  81.037  85.896  1.00 9.12  ? -2  DA  E C2    1 
ATOM   6774 N  N3    . DA  F 5 33  ? 88.788  81.025  84.638  1.00 1.43  ? -2  DA  E N3    1 
ATOM   6775 C  C4    . DA  F 5 33  ? 89.034  82.195  84.052  1.00 1.55  ? -2  DA  E C4    1 
ATOM   6776 P  P     . DA  F 5 34  ? 83.846  81.429  80.361  1.00 1.85  ? -1  DA  E P     1 
ATOM   6777 O  OP1   . DA  F 5 34  ? 82.902  80.769  79.455  1.00 6.19  ? -1  DA  E OP1   1 
ATOM   6778 O  OP2   . DA  F 5 34  ? 83.696  82.864  80.653  1.00 9.03  ? -1  DA  E OP2   1 
ATOM   6779 O  "O5'" . DA  F 5 34  ? 83.820  80.665  81.764  1.00 9.87  ? -1  DA  E "O5'" 1 
ATOM   6780 C  "C5'" . DA  F 5 34  ? 83.979  79.272  81.832  1.00 7.08  ? -1  DA  E "C5'" 1 
ATOM   6781 C  "C4'" . DA  F 5 34  ? 83.731  78.756  83.244  1.00 7.29  ? -1  DA  E "C4'" 1 
ATOM   6782 O  "O4'" . DA  F 5 34  ? 84.705  79.335  84.150  1.00 9.06  ? -1  DA  E "O4'" 1 
ATOM   6783 C  "C3'" . DA  F 5 34  ? 82.369  79.143  83.800  1.00 3.98  ? -1  DA  E "C3'" 1 
ATOM   6784 O  "O3'" . DA  F 5 34  ? 81.851  78.108  84.607  1.00 2.47  ? -1  DA  E "O3'" 1 
ATOM   6785 C  "C2'" . DA  F 5 34  ? 82.641  80.389  84.635  1.00 1.70  ? -1  DA  E "C2'" 1 
ATOM   6786 C  "C1'" . DA  F 5 34  ? 84.064  80.159  85.103  1.00 1.16  ? -1  DA  E "C1'" 1 
ATOM   6787 N  N9    . DA  F 5 34  ? 84.839  81.377  85.322  1.00 8.10  ? -1  DA  E N9    1 
ATOM   6788 C  C8    . DA  F 5 34  ? 84.995  82.412  84.466  1.00 1.44  ? -1  DA  E C8    1 
ATOM   6789 N  N7    . DA  F 5 34  ? 85.700  83.398  84.947  1.00 2.61  ? -1  DA  E N7    1 
ATOM   6790 C  C5    . DA  F 5 34  ? 85.987  83.000  86.232  1.00 8.16  ? -1  DA  E C5    1 
ATOM   6791 C  C6    . DA  F 5 34  ? 86.702  83.608  87.272  1.00 3.08  ? -1  DA  E C6    1 
ATOM   6792 N  N6    . DA  F 5 34  ? 87.281  84.800  87.162  1.00 9.79  ? -1  DA  E N6    1 
ATOM   6793 N  N1    . DA  F 5 34  ? 86.804  82.938  88.439  1.00 2.64  ? -1  DA  E N1    1 
ATOM   6794 C  C2    . DA  F 5 34  ? 86.224  81.749  88.539  1.00 5.31  ? -1  DA  E C2    1 
ATOM   6795 N  N3    . DA  F 5 34  ? 85.535  81.079  87.630  1.00 3.11  ? -1  DA  E N3    1 
ATOM   6796 C  C4    . DA  F 5 34  ? 85.456  81.764  86.487  1.00 9.08  ? -1  DA  E C4    1 
ATOM   6797 P  P     . DG  G 6 1   ? 79.409  83.506  84.533  1.00 3.64  ? 1   DG  G P     1 
ATOM   6798 O  OP1   . DG  G 6 1   ? 78.109  82.903  84.233  1.00 4.31  ? 1   DG  G OP1   1 
ATOM   6799 O  OP2   . DG  G 6 1   ? 79.552  84.967  84.448  1.00 5.09  ? 1   DG  G OP2   1 
ATOM   6800 O  "O5'" . DG  G 6 1   ? 79.731  83.099  86.022  1.00 9.36  ? 1   DG  G "O5'" 1 
ATOM   6801 C  "C5'" . DG  G 6 1   ? 79.614  81.760  86.427  1.00 0.28  ? 1   DG  G "C5'" 1 
ATOM   6802 C  "C4'" . DG  G 6 1   ? 80.085  81.624  87.845  1.00 7.14  ? 1   DG  G "C4'" 1 
ATOM   6803 O  "O4'" . DG  G 6 1   ? 81.534  81.694  87.854  1.00 8.88  ? 1   DG  G "O4'" 1 
ATOM   6804 C  "C3'" . DG  G 6 1   ? 79.634  82.762  88.726  1.00 0.24  ? 1   DG  G "C3'" 1 
ATOM   6805 O  "O3'" . DG  G 6 1   ? 78.410  82.497  89.371  1.00 5.19  ? 1   DG  G "O3'" 1 
ATOM   6806 C  "C2'" . DG  G 6 1   ? 80.757  82.863  89.745  1.00 3.23  ? 1   DG  G "C2'" 1 
ATOM   6807 C  "C1'" . DG  G 6 1   ? 81.971  82.537  88.902  1.00 8.56  ? 1   DG  G "C1'" 1 
ATOM   6808 N  N9    . DG  G 6 1   ? 82.708  83.708  88.396  1.00 5.55  ? 1   DG  G N9    1 
ATOM   6809 C  C8    . DG  G 6 1   ? 82.727  84.228  87.130  1.00 6.87  ? 1   DG  G C8    1 
ATOM   6810 N  N7    . DG  G 6 1   ? 83.495  85.278  87.014  1.00 4.50  ? 1   DG  G N7    1 
ATOM   6811 C  C5    . DG  G 6 1   ? 84.004  85.462  88.287  1.00 6.25  ? 1   DG  G C5    1 
ATOM   6812 C  C6    . DG  G 6 1   ? 84.900  86.431  88.796  1.00 2.87  ? 1   DG  G C6    1 
ATOM   6813 O  O6    . DG  G 6 1   ? 85.450  87.358  88.208  1.00 0.06  ? 1   DG  G O6    1 
ATOM   6814 N  N1    . DG  G 6 1   ? 85.167  86.233  90.152  1.00 5.74  ? 1   DG  G N1    1 
ATOM   6815 C  C2    . DG  G 6 1   ? 84.623  85.240  90.899  1.00 3.08  ? 1   DG  G C2    1 
ATOM   6816 N  N2    . DG  G 6 1   ? 84.967  85.198  92.186  1.00 5.14  ? 1   DG  G N2    1 
ATOM   6817 N  N3    . DG  G 6 1   ? 83.791  84.336  90.437  1.00 9.13  ? 1   DG  G N3    1 
ATOM   6818 C  C4    . DG  G 6 1   ? 83.536  84.497  89.133  1.00 4.23  ? 1   DG  G C4    1 
ATOM   6819 P  P     . DG  G 6 2   ? 77.501  83.770  89.687  1.00 3.68  ? 2   DG  G P     1 
ATOM   6820 O  OP1   . DG  G 6 2   ? 76.153  83.277  89.971  1.00 9.29  ? 2   DG  G OP1   1 
ATOM   6821 O  OP2   . DG  G 6 2   ? 77.729  84.770  88.637  1.00 9.34  ? 2   DG  G OP2   1 
ATOM   6822 O  "O5'" . DG  G 6 2   ? 78.113  84.308  91.048  1.00 8.41  ? 2   DG  G "O5'" 1 
ATOM   6823 C  "C5'" . DG  G 6 2   ? 78.351  85.669  91.215  1.00 9.17  ? 2   DG  G "C5'" 1 
ATOM   6824 C  "C4'" . DG  G 6 2   ? 79.091  85.902  92.506  1.00 2.25  ? 2   DG  G "C4'" 1 
ATOM   6825 O  "O4'" . DG  G 6 2   ? 80.493  85.616  92.315  1.00 0.84  ? 2   DG  G "O4'" 1 
ATOM   6826 C  "C3'" . DG  G 6 2   ? 79.005  87.326  93.042  1.00 2.24  ? 2   DG  G "C3'" 1 
ATOM   6827 O  "O3'" . DG  G 6 2   ? 78.007  87.424  94.014  1.00 3.11  ? 2   DG  G "O3'" 1 
ATOM   6828 C  "C2'" . DG  G 6 2   ? 80.376  87.512  93.667  1.00 1.72  ? 2   DG  G "C2'" 1 
ATOM   6829 C  "C1'" . DG  G 6 2   ? 81.261  86.703  92.751  1.00 6.04  ? 2   DG  G "C1'" 1 
ATOM   6830 N  N9    . DG  G 6 2   ? 81.774  87.444  91.611  1.00 4.11  ? 2   DG  G N9    1 
ATOM   6831 C  C8    . DG  G 6 2   ? 81.413  87.325  90.302  1.00 8.13  ? 2   DG  G C8    1 
ATOM   6832 N  N7    . DG  G 6 2   ? 82.066  88.123  89.518  1.00 1.82  ? 2   DG  G N7    1 
ATOM   6833 C  C5    . DG  G 6 2   ? 82.923  88.799  90.366  1.00 6.99  ? 2   DG  G C5    1 
ATOM   6834 C  C6    . DG  G 6 2   ? 83.883  89.787  90.090  1.00 2.37  ? 2   DG  G C6    1 
ATOM   6835 O  O6    . DG  G 6 2   ? 84.171  90.273  89.005  1.00 5.71  ? 2   DG  G O6    1 
ATOM   6836 N  N1    . DG  G 6 2   ? 84.548  90.209  91.245  1.00 3.46  ? 2   DG  G N1    1 
ATOM   6837 C  C2    . DG  G 6 2   ? 84.286  89.713  92.489  1.00 0.54  ? 2   DG  G C2    1 
ATOM   6838 N  N2    . DG  G 6 2   ? 84.993  90.216  93.502  1.00 2.26  ? 2   DG  G N2    1 
ATOM   6839 N  N3    . DG  G 6 2   ? 83.392  88.793  92.744  1.00 6.61  ? 2   DG  G N3    1 
ATOM   6840 C  C4    . DG  G 6 2   ? 82.752  88.389  91.647  1.00 4.94  ? 2   DG  G C4    1 
ATOM   6841 P  P     . DC  G 6 3   ? 77.292  88.827  94.288  1.00 5.16  ? 3   DC  G P     1 
ATOM   6842 O  OP1   . DC  G 6 3   ? 76.236  88.599  95.284  1.00 1.72  ? 3   DC  G OP1   1 
ATOM   6843 O  OP2   . DC  G 6 3   ? 76.982  89.460  92.995  1.00 5.68  ? 3   DC  G OP2   1 
ATOM   6844 O  "O5'" . DC  G 6 3   ? 78.433  89.700  94.956  1.00 9.94  ? 3   DC  G "O5'" 1 
ATOM   6845 C  "C5'" . DC  G 6 3   ? 79.022  89.286  96.175  1.00 8.14  ? 3   DC  G "C5'" 1 
ATOM   6846 C  "C4'" . DC  G 6 3   ? 80.057  90.287  96.602  1.00 5.91  ? 3   DC  G "C4'" 1 
ATOM   6847 O  "O4'" . DC  G 6 3   ? 81.093  90.365  95.597  1.00 9.73  ? 3   DC  G "O4'" 1 
ATOM   6848 C  "C3'" . DC  G 6 3   ? 79.455  91.674  96.723  1.00 8.99  ? 3   DC  G "C3'" 1 
ATOM   6849 O  "O3'" . DC  G 6 3   ? 79.374  92.078  98.063  1.00 5.93  ? 3   DC  G "O3'" 1 
ATOM   6850 C  "C2'" . DC  G 6 3   ? 80.367  92.581  95.917  1.00 0.29  ? 3   DC  G "C2'" 1 
ATOM   6851 C  "C1'" . DC  G 6 3   ? 81.502  91.693  95.440  1.00 0.91  ? 3   DC  G "C1'" 1 
ATOM   6852 N  N1    . DC  G 6 3   ? 81.829  91.964  94.020  1.00 0.62  ? 3   DC  G N1    1 
ATOM   6853 C  C2    . DC  G 6 3   ? 82.845  92.859  93.721  1.00 4.49  ? 3   DC  G C2    1 
ATOM   6854 O  O2    . DC  G 6 3   ? 83.471  93.370  94.636  1.00 3.72  ? 3   DC  G O2    1 
ATOM   6855 N  N3    . DC  G 6 3   ? 83.110  93.149  92.440  1.00 9.72  ? 3   DC  G N3    1 
ATOM   6856 C  C4    . DC  G 6 3   ? 82.417  92.576  91.484  1.00 1.65  ? 3   DC  G C4    1 
ATOM   6857 N  N4    . DC  G 6 3   ? 82.727  92.885  90.228  1.00 9.70  ? 3   DC  G N4    1 
ATOM   6858 C  C5    . DC  G 6 3   ? 81.369  91.655  91.762  1.00 7.64  ? 3   DC  G C5    1 
ATOM   6859 C  C6    . DC  G 6 3   ? 81.108  91.389  93.034  1.00 8.21  ? 3   DC  G C6    1 
ATOM   6860 P  P     . DA  G 6 4   ? 78.574  93.410  98.456  1.00 6.30  ? 4   DA  G P     1 
ATOM   6861 O  OP1   . DA  G 6 4   ? 78.279  93.307  99.894  1.00 6.66  ? 4   DA  G OP1   1 
ATOM   6862 O  OP2   . DA  G 6 4   ? 77.487  93.633  97.492  1.00 4.74  ? 4   DA  G OP2   1 
ATOM   6863 O  "O5'" . DA  G 6 4   ? 79.595  94.593  98.209  1.00 0.10  ? 4   DA  G "O5'" 1 
ATOM   6864 C  "C5'" . DA  G 6 4   ? 80.764  94.720  98.964  1.00 3.50  ? 4   DA  G "C5'" 1 
ATOM   6865 C  "C4'" . DA  G 6 4   ? 81.632  95.776  98.346  1.00 4.89  ? 4   DA  G "C4'" 1 
ATOM   6866 O  "O4'" . DA  G 6 4   ? 81.994  95.402  97.009  1.00 7.27  ? 4   DA  G "O4'" 1 
ATOM   6867 C  "C3'" . DA  G 6 4   ? 80.946  97.108  98.211  1.00 4.66  ? 4   DA  G "C3'" 1 
ATOM   6868 O  "O3'" . DA  G 6 4   ? 81.169  97.852  99.378  1.00 4.54  ? 4   DA  G "O3'" 1 
ATOM   6869 C  "C2'" . DA  G 6 4   ? 81.606  97.748  96.991  1.00 1.35  ? 4   DA  G "C2'" 1 
ATOM   6870 C  "C1'" . DA  G 6 4   ? 82.205  96.568  96.246  1.00 0.08  ? 4   DA  G "C1'" 1 
ATOM   6871 N  N9    . DA  G 6 4   ? 81.750  96.360  94.872  1.00 7.55  ? 4   DA  G N9    1 
ATOM   6872 C  C8    . DA  G 6 4   ? 80.826  95.469  94.434  1.00 3.17  ? 4   DA  G C8    1 
ATOM   6873 N  N7    . DA  G 6 4   ? 80.662  95.479  93.138  1.00 9.81  ? 4   DA  G N7    1 
ATOM   6874 C  C5    . DA  G 6 4   ? 81.535  96.448  92.703  1.00 2.17  ? 4   DA  G C5    1 
ATOM   6875 C  C6    . DA  G 6 4   ? 81.835  96.948  91.428  1.00 3.36  ? 4   DA  G C6    1 
ATOM   6876 N  N6    . DA  G 6 4   ? 81.258  96.515  90.312  1.00 5.21  ? 4   DA  G N6    1 
ATOM   6877 N  N1    . DA  G 6 4   ? 82.753  97.910  91.340  1.00 7.52  ? 4   DA  G N1    1 
ATOM   6878 C  C2    . DA  G 6 4   ? 83.330  98.347  92.453  1.00 4.61  ? 4   DA  G C2    1 
ATOM   6879 N  N3    . DA  G 6 4   ? 83.133  97.956  93.699  1.00 1.22  ? 4   DA  G N3    1 
ATOM   6880 C  C4    . DA  G 6 4   ? 82.210  97.002  93.755  1.00 3.09  ? 4   DA  G C4    1 
ATOM   6881 P  P     . DA  G 6 5   ? 80.277  99.134  99.706  1.00 5.02  ? 5   DA  G P     1 
ATOM   6882 O  OP1   . DA  G 6 5   ? 80.657  99.541  101.057 1.00 6.71  ? 5   DA  G OP1   1 
ATOM   6883 O  OP2   . DA  G 6 5   ? 78.877  98.809  99.426  1.00 7.67  ? 5   DA  G OP2   1 
ATOM   6884 O  "O5'" . DA  G 6 5   ? 80.773  100.241 98.668  1.00 1.27  ? 5   DA  G "O5'" 1 
ATOM   6885 C  "C5'" . DA  G 6 5   ? 82.087  100.758 98.746  1.00 0.20  ? 5   DA  G "C5'" 1 
ATOM   6886 C  "C4'" . DA  G 6 5   ? 82.348  101.715 97.615  1.00 5.16  ? 5   DA  G "C4'" 1 
ATOM   6887 O  "O4'" . DA  G 6 5   ? 82.357  101.025 96.341  1.00 8.07  ? 5   DA  G "O4'" 1 
ATOM   6888 C  "C3'" . DA  G 6 5   ? 81.266  102.795 97.503  1.00 0.10  ? 5   DA  G "C3'" 1 
ATOM   6889 O  "O3'" . DA  G 6 5   ? 81.824  104.071 97.430  1.00 6.69  ? 5   DA  G "O3'" 1 
ATOM   6890 C  "C2'" . DA  G 6 5   ? 80.583  102.460 96.188  1.00 6.84  ? 5   DA  G "C2'" 1 
ATOM   6891 C  "C1'" . DA  G 6 5   ? 81.730  101.869 95.419  1.00 4.46  ? 5   DA  G "C1'" 1 
ATOM   6892 N  N9    . DA  G 6 5   ? 81.300  101.147 94.237  1.00 9.12  ? 5   DA  G N9    1 
ATOM   6893 C  C8    . DA  G 6 5   ? 80.407  100.127 94.181  1.00 6.41  ? 5   DA  G C8    1 
ATOM   6894 N  N7    . DA  G 6 5   ? 80.151  99.718  92.969  1.00 0.02  ? 5   DA  G N7    1 
ATOM   6895 C  C5    . DA  G 6 5   ? 80.893  100.568 92.170  1.00 4.81  ? 5   DA  G C5    1 
ATOM   6896 C  C6    . DA  G 6 5   ? 81.055  100.661 90.782  1.00 8.56  ? 5   DA  G C6    1 
ATOM   6897 N  N6    . DA  G 6 5   ? 80.452  99.851  89.920  1.00 8.27  ? 5   DA  G N6    1 
ATOM   6898 N  N1    . DA  G 6 5   ? 81.873  101.622 90.310  1.00 6.46  ? 5   DA  G N1    1 
ATOM   6899 C  C2    . DA  G 6 5   ? 82.487  102.424 91.177  1.00 6.71  ? 5   DA  G C2    1 
ATOM   6900 N  N3    . DA  G 6 5   ? 82.412  102.431 92.499  1.00 5.75  ? 5   DA  G N3    1 
ATOM   6901 C  C4    . DA  G 6 5   ? 81.592  101.464 92.935  1.00 2.71  ? 5   DA  G C4    1 
ATOM   6902 P  P     . DT  G 6 6   ? 82.132  104.885 98.766  1.00 5.58  ? 6   DT  G P     1 
ATOM   6903 O  OP1   . DT  G 6 6   ? 82.980  106.026 98.388  1.00 6.69  ? 6   DT  G OP1   1 
ATOM   6904 O  OP2   . DT  G 6 6   ? 82.600  103.919 99.763  1.00 3.49  ? 6   DT  G OP2   1 
ATOM   6905 O  "O5'" . DT  G 6 6   ? 80.716  105.453 99.280  1.00 8.53  ? 6   DT  G "O5'" 1 
ATOM   6906 C  "C5'" . DT  G 6 6   ? 80.135  106.687 98.787  1.00 1.92  ? 6   DT  G "C5'" 1 
ATOM   6907 C  "C4'" . DT  G 6 6   ? 78.869  107.033 99.584  1.00 7.44  ? 6   DT  G "C4'" 1 
ATOM   6908 O  "O4'" . DT  G 6 6   ? 77.785  106.128 99.253  1.00 2.87  ? 6   DT  G "O4'" 1 
ATOM   6909 C  "C3'" . DT  G 6 6   ? 79.059  106.932 101.106 1.00 7.71  ? 6   DT  G "C3'" 1 
ATOM   6910 O  "O3'" . DT  G 6 6   ? 78.297  107.862 101.842 1.00 4.25  ? 6   DT  G "O3'" 1 
ATOM   6911 C  "C2'" . DT  G 6 6   ? 78.451  105.577 101.394 1.00 8.05  ? 6   DT  G "C2'" 1 
ATOM   6912 C  "C1'" . DT  G 6 6   ? 77.264  105.636 100.454 1.00 3.51  ? 6   DT  G "C1'" 1 
ATOM   6913 N  N1    . DT  G 6 6   ? 76.524  104.350 100.291 1.00 2.11  ? 6   DT  G N1    1 
ATOM   6914 C  C2    . DT  G 6 6   ? 75.261  104.360 99.747  1.00 7.64  ? 6   DT  G C2    1 
ATOM   6915 O  O2    . DT  G 6 6   ? 74.737  105.352 99.317  1.00 3.06  ? 6   DT  G O2    1 
ATOM   6916 N  N3    . DT  G 6 6   ? 74.649  103.149 99.704  1.00 7.30  ? 6   DT  G N3    1 
ATOM   6917 C  C4    . DT  G 6 6   ? 75.154  101.956 100.163 1.00 7.41  ? 6   DT  G C4    1 
ATOM   6918 O  O4    . DT  G 6 6   ? 74.540  100.908 100.078 1.00 2.18  ? 6   DT  G O4    1 
ATOM   6919 C  C5    . DT  G 6 6   ? 76.459  102.019 100.738 1.00 2.11  ? 6   DT  G C5    1 
ATOM   6920 C  C7    . DT  G 6 6   ? 77.097  100.774 101.272 1.00 1.96  ? 6   DT  G C7    1 
ATOM   6921 C  C6    . DT  G 6 6   ? 77.068  103.201 100.793 1.00 1.40  ? 6   DT  G C6    1 
ATOM   6922 P  P     . DC  G 6 7   ? 78.659  109.414 101.977 1.00 3.74  ? 7   DC  G P     1 
ATOM   6923 O  OP1   . DC  G 6 7   ? 79.276  109.882 100.741 1.00 0.24  ? 7   DC  G OP1   1 
ATOM   6924 O  OP2   . DC  G 6 7   ? 79.362  109.608 103.254 1.00 1.08  ? 7   DC  G OP2   1 
ATOM   6925 O  "O5'" . DC  G 6 7   ? 77.213  110.070 102.103 1.00 6.72  ? 7   DC  G "O5'" 1 
ATOM   6926 C  "C5'" . DC  G 6 7   ? 76.308  110.069 101.014 1.00 7.97  ? 7   DC  G "C5'" 1 
ATOM   6927 C  "C4'" . DC  G 6 7   ? 74.897  109.615 101.427 1.00 0.78  ? 7   DC  G "C4'" 1 
ATOM   6928 O  "O4'" . DC  G 6 7   ? 74.808  108.199 101.567 1.00 2.29  ? 7   DC  G "O4'" 1 
ATOM   6929 C  "C3'" . DC  G 6 7   ? 74.324  110.189 102.729 1.00 2.05  ? 7   DC  G "C3'" 1 
ATOM   6930 O  "O3'" . DC  G 6 7   ? 73.340  111.159 102.403 1.00 9.14  ? 7   DC  G "O3'" 1 
ATOM   6931 C  "C2'" . DC  G 6 7   ? 73.755  108.954 103.471 1.00 7.08  ? 7   DC  G "C2'" 1 
ATOM   6932 C  "C1'" . DC  G 6 7   ? 73.688  107.933 102.355 1.00 5.51  ? 7   DC  G "C1'" 1 
ATOM   6933 N  N1    . DC  G 6 7   ? 73.749  106.500 102.737 1.00 3.01  ? 7   DC  G N1    1 
ATOM   6934 C  C2    . DC  G 6 7   ? 72.648  105.669 102.498 1.00 8.32  ? 7   DC  G C2    1 
ATOM   6935 O  O2    . DC  G 6 7   ? 71.614  106.150 102.032 1.00 4.32  ? 7   DC  G O2    1 
ATOM   6936 N  N3    . DC  G 6 7   ? 72.742  104.355 102.799 1.00 9.20  ? 7   DC  G N3    1 
ATOM   6937 C  C4    . DC  G 6 7   ? 73.864  103.876 103.299 1.00 7.03  ? 7   DC  G C4    1 
ATOM   6938 N  N4    . DC  G 6 7   ? 73.913  102.574 103.577 1.00 4.75  ? 7   DC  G N4    1 
ATOM   6939 C  C5    . DC  G 6 7   ? 74.993  104.702 103.531 1.00 1.23  ? 7   DC  G C5    1 
ATOM   6940 C  C6    . DC  G 6 7   ? 74.893  105.990 103.238 1.00 9.73  ? 7   DC  G C6    1 
ATOM   6941 P  P     . DA  G 6 8   ? 72.626  112.053 103.519 1.00 1.57  ? 8   DA  G P     1 
ATOM   6942 O  OP1   . DA  G 6 8   ? 72.210  113.315 102.885 1.00 2.00  ? 8   DA  G OP1   1 
ATOM   6943 O  OP2   . DA  G 6 8   ? 73.486  112.118 104.712 1.00 4.28  ? 8   DA  G OP2   1 
ATOM   6944 O  "O5'" . DA  G 6 8   ? 71.317  111.214 103.852 1.00 4.01  ? 8   DA  G "O5'" 1 
ATOM   6945 C  "C5'" . DA  G 6 8   ? 70.347  111.039 102.836 1.00 1.44  ? 8   DA  G "C5'" 1 
ATOM   6946 C  "C4'" . DA  G 6 8   ? 69.180  110.200 103.314 1.00 7.26  ? 8   DA  G "C4'" 1 
ATOM   6947 O  "O4'" . DA  G 6 8   ? 69.593  108.856 103.618 1.00 1.86  ? 8   DA  G "O4'" 1 
ATOM   6948 C  "C3'" . DA  G 6 8   ? 68.484  110.736 104.544 1.00 6.41  ? 8   DA  G "C3'" 1 
ATOM   6949 O  "O3'" . DA  G 6 8   ? 67.099  110.734 104.253 1.00 7.51  ? 8   DA  G "O3'" 1 
ATOM   6950 C  "C2'" . DA  G 6 8   ? 68.880  109.747 105.658 1.00 2.08  ? 8   DA  G "C2'" 1 
ATOM   6951 C  "C1'" . DA  G 6 8   ? 69.138  108.471 104.886 1.00 5.98  ? 8   DA  G "C1'" 1 
ATOM   6952 N  N9    . DA  G 6 8   ? 70.180  107.625 105.430 1.00 7.46  ? 8   DA  G N9    1 
ATOM   6953 C  C8    . DA  G 6 8   ? 71.397  108.015 105.886 1.00 6.35  ? 8   DA  G C8    1 
ATOM   6954 N  N7    . DA  G 6 8   ? 72.154  107.031 106.267 1.00 5.94  ? 8   DA  G N7    1 
ATOM   6955 C  C5    . DA  G 6 8   ? 71.389  105.923 106.023 1.00 2.92  ? 8   DA  G C5    1 
ATOM   6956 C  C6    . DA  G 6 8   ? 71.626  104.563 106.217 1.00 7.29  ? 8   DA  G C6    1 
ATOM   6957 N  N6    . DA  G 6 8   ? 72.760  104.087 106.702 1.00 9.42  ? 8   DA  G N6    1 
ATOM   6958 N  N1    . DA  G 6 8   ? 70.656  103.707 105.874 1.00 4.23  ? 8   DA  G N1    1 
ATOM   6959 C  C2    . DA  G 6 8   ? 69.522  104.194 105.379 1.00 7.79  ? 8   DA  G C2    1 
ATOM   6960 N  N3    . DA  G 6 8   ? 69.186  105.458 105.155 1.00 0.53  ? 8   DA  G N3    1 
ATOM   6961 C  C4    . DA  G 6 8   ? 70.176  106.274 105.495 1.00 8.32  ? 8   DA  G C4    1 
ATOM   6962 P  P     . DT  G 6 9   ? 66.025  111.449 105.195 1.00 4.04  ? 9   DT  G P     1 
ATOM   6963 O  OP1   . DT  G 6 9   ? 64.889  111.799 104.322 1.00 6.07  ? 9   DT  G OP1   1 
ATOM   6964 O  OP2   . DT  G 6 9   ? 66.693  112.513 105.970 1.00 5.12  ? 9   DT  G OP2   1 
ATOM   6965 O  "O5'" . DT  G 6 9   ? 65.545  110.285 106.150 1.00 2.92  ? 9   DT  G "O5'" 1 
ATOM   6966 C  "C5'" . DT  G 6 9   ? 64.768  109.252 105.598 1.00 11.16 ? 9   DT  G "C5'" 1 
ATOM   6967 C  "C4'" . DT  G 6 9   ? 64.651  108.085 106.545 1.00 5.82  ? 9   DT  G "C4'" 1 
ATOM   6968 O  "O4'" . DT  G 6 9   ? 65.929  107.522 106.824 1.00 7.42  ? 9   DT  G "O4'" 1 
ATOM   6969 C  "C3'" . DT  G 6 9   ? 64.035  108.413 107.889 1.00 7.06  ? 9   DT  G "C3'" 1 
ATOM   6970 O  "O3'" . DT  G 6 9   ? 62.672  107.996 107.868 1.00 3.44  ? 9   DT  G "O3'" 1 
ATOM   6971 C  "C2'" . DT  G 6 9   ? 64.898  107.632 108.909 1.00 4.18  ? 9   DT  G "C2'" 1 
ATOM   6972 C  "C1'" . DT  G 6 9   ? 65.833  106.812 108.022 1.00 2.88  ? 9   DT  G "C1'" 1 
ATOM   6973 N  N1    . DT  G 6 9   ? 67.211  106.654 108.520 1.00 7.20  ? 9   DT  G N1    1 
ATOM   6974 C  C2    . DT  G 6 9   ? 67.748  105.398 108.619 1.00 4.73  ? 9   DT  G C2    1 
ATOM   6975 O  O2    . DT  G 6 9   ? 67.122  104.389 108.386 1.00 5.69  ? 9   DT  G O2    1 
ATOM   6976 N  N3    . DT  G 6 9   ? 69.045  105.362 109.037 1.00 3.20  ? 9   DT  G N3    1 
ATOM   6977 C  C4    . DT  G 6 9   ? 69.857  106.431 109.319 1.00 9.99  ? 9   DT  G C4    1 
ATOM   6978 O  O4    . DT  G 6 9   ? 71.017  106.285 109.678 1.00 3.18  ? 9   DT  G O4    1 
ATOM   6979 C  C5    . DT  G 6 9   ? 69.240  107.729 109.166 1.00 11.97 ? 9   DT  G C5    1 
ATOM   6980 C  C7    . DT  G 6 9   ? 70.014  108.985 109.442 1.00 3.89  ? 9   DT  G C7    1 
ATOM   6981 C  C6    . DT  G 6 9   ? 67.968  107.773 108.761 1.00 7.84  ? 9   DT  G C6    1 
ATOM   6982 P  P     . DC  G 6 10  ? 61.712  108.164 109.142 1.00 11.87 ? 10  DC  G P     1 
ATOM   6983 O  OP1   . DC  G 6 10  ? 60.331  108.104 108.621 1.00 19.29 ? 10  DC  G OP1   1 
ATOM   6984 O  OP2   . DC  G 6 10  ? 62.141  109.339 109.927 1.00 13.32 ? 10  DC  G OP2   1 
ATOM   6985 O  "O5'" . DC  G 6 10  ? 61.986  106.851 110.003 1.00 16.70 ? 10  DC  G "O5'" 1 
ATOM   6986 C  "C5'" . DC  G 6 10  ? 61.690  105.592 109.449 1.00 18.82 ? 10  DC  G "C5'" 1 
ATOM   6987 C  "C4'" . DC  G 6 10  ? 62.269  104.482 110.296 1.00 12.92 ? 10  DC  G "C4'" 1 
ATOM   6988 O  "O4'" . DC  G 6 10  ? 63.705  104.580 110.364 1.00 16.93 ? 10  DC  G "O4'" 1 
ATOM   6989 C  "C3'" . DC  G 6 10  ? 61.762  104.477 111.737 1.00 13.59 ? 10  DC  G "C3'" 1 
ATOM   6990 O  "O3'" . DC  G 6 10  ? 61.055  103.290 111.967 1.00 19.01 ? 10  DC  G "O3'" 1 
ATOM   6991 C  "C2'" . DC  G 6 10  ? 63.026  104.583 112.600 1.00 18.65 ? 10  DC  G "C2'" 1 
ATOM   6992 C  "C1'" . DC  G 6 10  ? 64.122  104.169 111.637 1.00 13.18 ? 10  DC  G "C1'" 1 
ATOM   6993 N  N1    . DC  G 6 10  ? 65.437  104.776 111.924 1.00 20.04 ? 10  DC  G N1    1 
ATOM   6994 C  C2    . DC  G 6 10  ? 66.534  103.948 112.089 1.00 11.62 ? 10  DC  G C2    1 
ATOM   6995 O  O2    . DC  G 6 10  ? 66.374  102.729 111.984 1.00 20.02 ? 10  DC  G O2    1 
ATOM   6996 N  N3    . DC  G 6 10  ? 67.737  104.500 112.339 1.00 17.01 ? 10  DC  G N3    1 
ATOM   6997 C  C4    . DC  G 6 10  ? 67.854  105.816 112.435 1.00 15.45 ? 10  DC  G C4    1 
ATOM   6998 N  N4    . DC  G 6 10  ? 69.058  106.315 112.692 1.00 19.01 ? 10  DC  G N4    1 
ATOM   6999 C  C5    . DC  G 6 10  ? 66.744  106.682 112.273 1.00 18.59 ? 10  DC  G C5    1 
ATOM   7000 C  C6    . DC  G 6 10  ? 65.563  106.123 112.020 1.00 21.29 ? 10  DC  G C6    1 
ATOM   7001 P  P     . DA  G 6 11  ? 60.267  103.043 113.340 1.00 29.83 ? 11  DA  G P     1 
ATOM   7002 O  OP1   . DA  G 6 11  ? 59.217  102.046 113.038 1.00 27.09 ? 11  DA  G OP1   1 
ATOM   7003 O  OP2   . DA  G 6 11  ? 59.884  104.355 113.905 1.00 36.39 ? 11  DA  G OP2   1 
ATOM   7004 O  "O5'" . DA  G 6 11  ? 61.350  102.363 114.297 1.00 35.63 ? 11  DA  G "O5'" 1 
ATOM   7005 C  "C5'" . DA  G 6 11  ? 61.881  101.117 113.935 1.00 34.34 ? 11  DA  G "C5'" 1 
ATOM   7006 C  "C4'" . DA  G 6 11  ? 63.199  100.834 114.639 1.00 32.21 ? 11  DA  G "C4'" 1 
ATOM   7007 O  "O4'" . DA  G 6 11  ? 64.188  101.851 114.404 1.00 34.12 ? 11  DA  G "O4'" 1 
ATOM   7008 C  "C3'" . DA  G 6 11  ? 63.108  100.724 116.149 1.00 34.85 ? 11  DA  G "C3'" 1 
ATOM   7009 O  "O3'" . DA  G 6 11  ? 62.818  99.380  116.463 1.00 30.80 ? 11  DA  G "O3'" 1 
ATOM   7010 C  "C2'" . DA  G 6 11  ? 64.494  101.179 116.634 1.00 34.75 ? 11  DA  G "C2'" 1 
ATOM   7011 C  "C1'" . DA  G 6 11  ? 65.203  101.635 115.353 1.00 34.55 ? 11  DA  G "C1'" 1 
ATOM   7012 N  N9    . DA  G 6 11  ? 66.005  102.846 115.529 1.00 33.18 ? 11  DA  G N9    1 
ATOM   7013 C  C8    . DA  G 6 11  ? 65.572  104.141 115.549 1.00 31.07 ? 11  DA  G C8    1 
ATOM   7014 N  N7    . DA  G 6 11  ? 66.532  105.017 115.742 1.00 34.02 ? 11  DA  G N7    1 
ATOM   7015 C  C5    . DA  G 6 11  ? 67.670  104.241 115.852 1.00 27.08 ? 11  DA  G C5    1 
ATOM   7016 C  C6    . DA  G 6 11  ? 69.028  104.563 116.057 1.00 34.80 ? 11  DA  G C6    1 
ATOM   7017 N  N6    . DA  G 6 11  ? 69.474  105.812 116.194 1.00 36.01 ? 11  DA  G N6    1 
ATOM   7018 N  N1    . DA  G 6 11  ? 69.911  103.547 116.113 1.00 29.44 ? 11  DA  G N1    1 
ATOM   7019 C  C2    . DA  G 6 11  ? 69.459  102.296 115.973 1.00 28.26 ? 11  DA  G C2    1 
ATOM   7020 N  N3    . DA  G 6 11  ? 68.215  101.874 115.773 1.00 29.25 ? 11  DA  G N3    1 
ATOM   7021 C  C4    . DA  G 6 11  ? 67.362  102.903 115.722 1.00 30.07 ? 11  DA  G C4    1 
ATOM   7022 P  P     . DA  G 6 12  ? 62.800  98.853  117.980 1.00 47.49 ? 12  DA  G P     1 
ATOM   7023 O  OP1   . DA  G 6 12  ? 62.016  97.600  117.987 1.00 44.09 ? 12  DA  G OP1   1 
ATOM   7024 O  OP2   . DA  G 6 12  ? 62.402  99.960  118.878 1.00 41.52 ? 12  DA  G OP2   1 
ATOM   7025 O  "O5'" . DA  G 6 12  ? 64.328  98.500  118.283 1.00 40.04 ? 12  DA  G "O5'" 1 
ATOM   7026 C  "C5'" . DA  G 6 12  ? 65.023  97.599  117.431 1.00 41.56 ? 12  DA  G "C5'" 1 
ATOM   7027 C  "C4'" . DA  G 6 12  ? 66.496  97.508  117.800 1.00 44.79 ? 12  DA  G "C4'" 1 
ATOM   7028 O  "O4'" . DA  G 6 12  ? 67.147  98.798  117.687 1.00 41.90 ? 12  DA  G "O4'" 1 
ATOM   7029 C  "C3'" . DA  G 6 12  ? 66.744  97.040  119.226 1.00 43.23 ? 12  DA  G "C3'" 1 
ATOM   7030 O  "O3'" . DA  G 6 12  ? 67.833  96.121  119.221 1.00 43.10 ? 12  DA  G "O3'" 1 
ATOM   7031 C  "C2'" . DA  G 6 12  ? 67.055  98.337  119.980 1.00 46.94 ? 12  DA  G "C2'" 1 
ATOM   7032 C  "C1'" . DA  G 6 12  ? 67.771  99.130  118.911 1.00 42.92 ? 12  DA  G "C1'" 1 
ATOM   7033 N  N9    . DA  G 6 12  ? 67.730  100.584 119.069 1.00 42.11 ? 12  DA  G N9    1 
ATOM   7034 C  C8    . DA  G 6 12  ? 66.627  101.386 119.103 1.00 45.40 ? 12  DA  G C8    1 
ATOM   7035 N  N7    . DA  G 6 12  ? 66.904  102.664 119.215 1.00 40.87 ? 12  DA  G N7    1 
ATOM   7036 C  C5    . DA  G 6 12  ? 68.283  102.700 119.256 1.00 43.33 ? 12  DA  G C5    1 
ATOM   7037 C  C6    . DA  G 6 12  ? 69.202  103.758 119.373 1.00 41.80 ? 12  DA  G C6    1 
ATOM   7038 N  N6    . DA  G 6 12  ? 68.838  105.039 119.471 1.00 44.92 ? 12  DA  G N6    1 
ATOM   7039 N  N1    . DA  G 6 12  ? 70.517  103.450 119.384 1.00 47.43 ? 12  DA  G N1    1 
ATOM   7040 C  C2    . DA  G 6 12  ? 70.876  102.168 119.281 1.00 43.13 ? 12  DA  G C2    1 
ATOM   7041 N  N3    . DA  G 6 12  ? 70.104  101.088 119.166 1.00 46.50 ? 12  DA  G N3    1 
ATOM   7042 C  C4    . DA  G 6 12  ? 68.807  101.427 119.162 1.00 43.22 ? 12  DA  G C4    1 
ATOM   7043 P  P     . DT  G 6 13  ? 68.229  95.324  120.553 1.00 50.55 ? 13  DT  G P     1 
ATOM   7044 O  OP1   . DT  G 6 13  ? 68.842  94.035  120.147 1.00 45.30 ? 13  DT  G OP1   1 
ATOM   7045 O  OP2   . DT  G 6 13  ? 67.019  95.335  121.407 1.00 48.32 ? 13  DT  G OP2   1 
ATOM   7046 O  "O5'" . DT  G 6 13  ? 69.337  96.245  121.256 1.00 53.08 ? 13  DT  G "O5'" 1 
ATOM   7047 C  "C5'" . DT  G 6 13  ? 70.662  96.238  120.744 1.00 50.04 ? 13  DT  G "C5'" 1 
ATOM   7048 C  "C4'" . DT  G 6 13  ? 71.581  97.152  121.534 1.00 51.65 ? 13  DT  G "C4'" 1 
ATOM   7049 O  "O4'" . DT  G 6 13  ? 71.205  98.533  121.371 1.00 49.03 ? 13  DT  G "O4'" 1 
ATOM   7050 C  "C3'" . DT  G 6 13  ? 71.621  96.892  123.040 1.00 48.97 ? 13  DT  G "C3'" 1 
ATOM   7051 O  "O3'" . DT  G 6 13  ? 72.929  96.468  123.410 1.00 52.42 ? 13  DT  G "O3'" 1 
ATOM   7052 C  "C2'" . DT  G 6 13  ? 71.228  98.239  123.672 1.00 44.66 ? 13  DT  G "C2'" 1 
ATOM   7053 C  "C1'" . DT  G 6 13  ? 71.507  99.224  122.552 1.00 49.72 ? 13  DT  G "C1'" 1 
ATOM   7054 N  N1    . DT  G 6 13  ? 70.667  100.441 122.590 1.00 53.41 ? 13  DT  G N1    1 
ATOM   7055 C  C2    . DT  G 6 13  ? 71.273  101.673 122.650 1.00 49.16 ? 13  DT  G C2    1 
ATOM   7056 O  O2    . DT  G 6 13  ? 72.479  101.819 122.659 1.00 45.93 ? 13  DT  G O2    1 
ATOM   7057 N  N3    . DT  G 6 13  ? 70.412  102.738 122.666 1.00 52.47 ? 13  DT  G N3    1 
ATOM   7058 C  C4    . DT  G 6 13  ? 69.030  102.692 122.647 1.00 46.50 ? 13  DT  G C4    1 
ATOM   7059 O  O4    . DT  G 6 13  ? 68.344  103.706 122.666 1.00 50.99 ? 13  DT  G O4    1 
ATOM   7060 C  C5    . DT  G 6 13  ? 68.458  101.361 122.598 1.00 49.39 ? 13  DT  G C5    1 
ATOM   7061 C  C7    . DT  G 6 13  ? 66.971  101.173 122.573 1.00 53.47 ? 13  DT  G C7    1 
ATOM   7062 C  C6    . DT  G 6 13  ? 69.297  100.314 122.575 1.00 50.23 ? 13  DT  G C6    1 
ATOM   7063 P  P     . DT  G 6 14  ? 73.314  96.208  124.949 1.00 59.11 ? 14  DT  G P     1 
ATOM   7064 O  OP1   . DT  G 6 14  ? 74.303  95.103  124.965 1.00 50.81 ? 14  DT  G OP1   1 
ATOM   7065 O  OP2   . DT  G 6 14  ? 72.061  96.063  125.720 1.00 60.63 ? 14  DT  G OP2   1 
ATOM   7066 O  "O5'" . DT  G 6 14  ? 74.037  97.566  125.399 1.00 51.51 ? 14  DT  G "O5'" 1 
ATOM   7067 C  "C5'" . DT  G 6 14  ? 75.280  97.929  124.802 1.00 53.95 ? 14  DT  G "C5'" 1 
ATOM   7068 C  "C4'" . DT  G 6 14  ? 75.788  99.286  125.292 1.00 60.19 ? 14  DT  G "C4'" 1 
ATOM   7069 O  "O4'" . DT  G 6 14  ? 74.817  100.337 125.004 1.00 50.82 ? 14  DT  G "O4'" 1 
ATOM   7070 C  "C3'" . DT  G 6 14  ? 76.036  99.375  126.793 1.00 58.96 ? 14  DT  G "C3'" 1 
ATOM   7071 O  "O3'" . DT  G 6 14  ? 77.087  100.299 127.049 1.00 59.34 ? 14  DT  G "O3'" 1 
ATOM   7072 C  "C2'" . DT  G 6 14  ? 74.719  99.926  127.294 1.00 55.13 ? 14  DT  G "C2'" 1 
ATOM   7073 C  "C1'" . DT  G 6 14  ? 74.443  100.957 126.218 1.00 53.29 ? 14  DT  G "C1'" 1 
ATOM   7074 N  N1    . DT  G 6 14  ? 73.030  101.424 126.152 1.00 58.76 ? 14  DT  G N1    1 
ATOM   7075 C  C2    . DT  G 6 14  ? 72.774  102.770 125.978 1.00 55.51 ? 14  DT  G C2    1 
ATOM   7076 O  O2    . DT  G 6 14  ? 73.652  103.604 125.853 1.00 52.08 ? 14  DT  G O2    1 
ATOM   7077 N  N3    . DT  G 6 14  ? 71.444  103.100 125.943 1.00 60.01 ? 14  DT  G N3    1 
ATOM   7078 C  C4    . DT  G 6 14  ? 70.374  102.234 126.060 1.00 59.69 ? 14  DT  G C4    1 
ATOM   7079 O  O4    . DT  G 6 14  ? 69.214  102.613 126.018 1.00 55.65 ? 14  DT  G O4    1 
ATOM   7080 C  C5    . DT  G 6 14  ? 70.714  100.848 126.261 1.00 59.30 ? 14  DT  G C5    1 
ATOM   7081 C  C7    . DT  G 6 14  ? 69.629  99.826  126.416 1.00 54.92 ? 14  DT  G C7    1 
ATOM   7082 C  C6    . DT  G 6 14  ? 72.010  100.513 126.297 1.00 57.57 ? 14  DT  G C6    1 
ATOM   7083 P  P     . DT  G 6 15  ? 77.793  100.345 128.493 1.00 60.45 ? 15  DT  G P     1 
ATOM   7084 O  OP1   . DT  G 6 15  ? 78.601  99.112  128.603 1.00 61.53 ? 15  DT  G OP1   1 
ATOM   7085 O  OP2   . DT  G 6 15  ? 76.778  100.655 129.519 1.00 58.37 ? 15  DT  G OP2   1 
ATOM   7086 O  "O5'" . DT  G 6 15  ? 78.820  101.569 128.392 1.00 66.12 ? 15  DT  G "O5'" 1 
ATOM   7087 C  "C5'" . DT  G 6 15  ? 78.494  102.804 127.726 1.00 59.42 ? 15  DT  G "C5'" 1 
ATOM   7088 C  "C4'" . DT  G 6 15  ? 77.468  103.664 128.477 1.00 57.51 ? 15  DT  G "C4'" 1 
ATOM   7089 O  "O4'" . DT  G 6 15  ? 76.098  103.246 128.288 1.00 57.92 ? 15  DT  G "O4'" 1 
ATOM   7090 C  "C3'" . DT  G 6 15  ? 77.669  103.813 129.994 1.00 56.62 ? 15  DT  G "C3'" 1 
ATOM   7091 O  "O3'" . DT  G 6 15  ? 78.254  105.076 130.280 1.00 63.63 ? 15  DT  G "O3'" 1 
ATOM   7092 C  "C2'" . DT  G 6 15  ? 76.236  103.723 130.568 1.00 62.12 ? 15  DT  G "C2'" 1 
ATOM   7093 C  "C1'" . DT  G 6 15  ? 75.376  103.884 129.317 1.00 64.42 ? 15  DT  G "C1'" 1 
ATOM   7094 N  N1    . DT  G 6 15  ? 73.975  103.346 129.412 1.00 61.55 ? 15  DT  G N1    1 
ATOM   7095 C  C2    . DT  G 6 15  ? 72.915  104.213 129.233 1.00 64.39 ? 15  DT  G C2    1 
ATOM   7096 O  O2    . DT  G 6 15  ? 73.055  105.405 129.015 1.00 63.43 ? 15  DT  G O2    1 
ATOM   7097 N  N3    . DT  G 6 15  ? 71.677  103.637 129.331 1.00 64.25 ? 15  DT  G N3    1 
ATOM   7098 C  C4    . DT  G 6 15  ? 71.394  102.312 129.580 1.00 60.54 ? 15  DT  G C4    1 
ATOM   7099 O  O4    . DT  G 6 15  ? 70.245  101.890 129.645 1.00 62.95 ? 15  DT  G O4    1 
ATOM   7100 C  C5    . DT  G 6 15  ? 72.547  101.454 129.750 1.00 58.27 ? 15  DT  G C5    1 
ATOM   7101 C  C7    . DT  G 6 15  ? 72.361  99.996  130.021 1.00 59.69 ? 15  DT  G C7    1 
ATOM   7102 C  C6    . DT  G 6 15  ? 73.768  102.007 129.663 1.00 58.20 ? 15  DT  G C6    1 
HETATM 7103 MG MG    . MG  H 7 .   ? 114.224 110.380 87.206  1.00 57.86 ? 401 MG  A MG    1 
HETATM 7104 MG MG    . MG  I 7 .   ? 96.123  104.868 98.857  1.00 14.23 ? 402 MG  A MG    1 
HETATM 7105 MG MG    . MG  J 7 .   ? 77.963  79.346  82.565  1.00 56.01 ? 401 MG  B MG    1 
HETATM 7106 MG MG    . MG  K 7 .   ? 94.325  84.453  98.575  1.00 17.18 ? 402 MG  B MG    1 
# 
