data_9MR8
# 
_entry.id   9MR8 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MR8         pdb_00009mr8 10.2210/pdb9mr8/pdb 
WWPDB D_1000291598 ?            ?                   
EMDB  EMD-48555    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'Structure model' 1 1 2025-03-19 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation_author.name'    
3 2 'Structure model' '_em_admin.last_update'    
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MR8 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-07 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of D421-Truncated Tau Fibril' 
_pdbx_database_related.db_id          EMD-48555 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              meihong@mit.edu 
_pdbx_contact_author.name_first         Mei 
_pdbx_contact_author.name_last          Hong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5255-5858 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'El Mammeri, N.' 1 0000-0002-9979-3359 
'Duan, P.'       2 0000-0002-7395-4353 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Mol.Biol. 
_citation.journal_id_ASTM           JMOBAK 
_citation.journal_id_CSD            0070 
_citation.journal_id_ISSN           1089-8638 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            437 
_citation.language                  ? 
_citation.page_first                169051 
_citation.page_last                 169051 
_citation.title                     'Structures of Delta D421 Truncated Tau Fibrils.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jmb.2025.169051 
_citation.pdbx_database_id_PubMed   40021051 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'El Mammeri, N.' 1 ? 
primary 'Duan, P.'       2 ? 
primary 'Hong, M.'       3 ? 
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Microtubule-associated protein tau' 
_entity.formula_weight             9667.116 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS
KIGSLDNITH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS
KIGSLDNITH
;
_entity_poly.pdbx_strand_id                 C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1  GLY n 
1 2  LYS n 
1 3  VAL n 
1 4  GLN n 
1 5  ILE n 
1 6  ILE n 
1 7  ASN n 
1 8  LYS n 
1 9  LYS n 
1 10 LEU n 
1 11 ASP n 
1 12 LEU n 
1 13 SER n 
1 14 ASN n 
1 15 VAL n 
1 16 GLN n 
1 17 SER n 
1 18 LYS n 
1 19 CYS n 
1 20 GLY n 
1 21 SER n 
1 22 LYS n 
1 23 ASP n 
1 24 ASN n 
1 25 ILE n 
1 26 LYS n 
1 27 HIS n 
1 28 VAL n 
1 29 PRO n 
1 30 GLY n 
1 31 GLY n 
1 32 GLY n 
1 33 SER n 
1 34 VAL n 
1 35 GLN n 
1 36 ILE n 
1 37 VAL n 
1 38 TYR n 
1 39 LYS n 
1 40 PRO n 
1 41 VAL n 
1 42 ASP n 
1 43 LEU n 
1 44 SER n 
1 45 LYS n 
1 46 VAL n 
1 47 THR n 
1 48 SER n 
1 49 LYS n 
1 50 CYS n 
1 51 GLY n 
1 52 SER n 
1 53 LEU n 
1 54 GLY n 
1 55 ASN n 
1 56 ILE n 
1 57 HIS n 
1 58 HIS n 
1 59 LYS n 
1 60 PRO n 
1 61 GLY n 
1 62 GLY n 
1 63 GLY n 
1 64 GLN n 
1 65 VAL n 
1 66 GLU n 
1 67 VAL n 
1 68 LYS n 
1 69 SER n 
1 70 GLU n 
1 71 LYS n 
1 72 LEU n 
1 73 ASP n 
1 74 PHE n 
1 75 LYS n 
1 76 ASP n 
1 77 ARG n 
1 78 VAL n 
1 79 GLN n 
1 80 SER n 
1 81 LYS n 
1 82 ILE n 
1 83 GLY n 
1 84 SER n 
1 85 LEU n 
1 86 ASP n 
1 87 ASN n 
1 88 ILE n 
1 89 THR n 
1 90 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   90 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'MAPT, MAPTL, MTBT1, TAU' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1  GLY 1  273 273 GLY GLY C . n 
A 1 2  LYS 2  274 274 LYS LYS C . n 
A 1 3  VAL 3  275 275 VAL VAL C . n 
A 1 4  GLN 4  276 276 GLN GLN C . n 
A 1 5  ILE 5  277 277 ILE ILE C . n 
A 1 6  ILE 6  278 278 ILE ILE C . n 
A 1 7  ASN 7  279 279 ASN ASN C . n 
A 1 8  LYS 8  280 280 LYS LYS C . n 
A 1 9  LYS 9  281 281 LYS LYS C . n 
A 1 10 LEU 10 282 282 LEU LEU C . n 
A 1 11 ASP 11 283 283 ASP ASP C . n 
A 1 12 LEU 12 284 284 LEU LEU C . n 
A 1 13 SER 13 285 285 SER SER C . n 
A 1 14 ASN 14 286 286 ASN ASN C . n 
A 1 15 VAL 15 287 287 VAL VAL C . n 
A 1 16 GLN 16 288 288 GLN GLN C . n 
A 1 17 SER 17 289 289 SER SER C . n 
A 1 18 LYS 18 290 290 LYS LYS C . n 
A 1 19 CYS 19 291 291 CYS CYS C . n 
A 1 20 GLY 20 292 292 GLY GLY C . n 
A 1 21 SER 21 293 293 SER SER C . n 
A 1 22 LYS 22 294 294 LYS LYS C . n 
A 1 23 ASP 23 295 295 ASP ASP C . n 
A 1 24 ASN 24 296 296 ASN ASN C . n 
A 1 25 ILE 25 297 297 ILE ILE C . n 
A 1 26 LYS 26 298 298 LYS LYS C . n 
A 1 27 HIS 27 299 299 HIS HIS C . n 
A 1 28 VAL 28 300 300 VAL VAL C . n 
A 1 29 PRO 29 301 301 PRO PRO C . n 
A 1 30 GLY 30 302 302 GLY GLY C . n 
A 1 31 GLY 31 303 303 GLY GLY C . n 
A 1 32 GLY 32 304 304 GLY GLY C . n 
A 1 33 SER 33 305 305 SER SER C . n 
A 1 34 VAL 34 306 306 VAL VAL C . n 
A 1 35 GLN 35 307 307 GLN GLN C . n 
A 1 36 ILE 36 308 308 ILE ILE C . n 
A 1 37 VAL 37 309 309 VAL VAL C . n 
A 1 38 TYR 38 310 310 TYR TYR C . n 
A 1 39 LYS 39 311 311 LYS LYS C . n 
A 1 40 PRO 40 312 312 PRO PRO C . n 
A 1 41 VAL 41 313 313 VAL VAL C . n 
A 1 42 ASP 42 314 314 ASP ASP C . n 
A 1 43 LEU 43 315 315 LEU LEU C . n 
A 1 44 SER 44 316 316 SER SER C . n 
A 1 45 LYS 45 317 317 LYS LYS C . n 
A 1 46 VAL 46 318 318 VAL VAL C . n 
A 1 47 THR 47 319 319 THR THR C . n 
A 1 48 SER 48 320 320 SER SER C . n 
A 1 49 LYS 49 321 321 LYS LYS C . n 
A 1 50 CYS 50 322 322 CYS CYS C . n 
A 1 51 GLY 51 323 323 GLY GLY C . n 
A 1 52 SER 52 324 324 SER SER C . n 
A 1 53 LEU 53 325 325 LEU LEU C . n 
A 1 54 GLY 54 326 326 GLY GLY C . n 
A 1 55 ASN 55 327 327 ASN ASN C . n 
A 1 56 ILE 56 328 328 ILE ILE C . n 
A 1 57 HIS 57 329 329 HIS HIS C . n 
A 1 58 HIS 58 330 330 HIS HIS C . n 
A 1 59 LYS 59 331 331 LYS LYS C . n 
A 1 60 PRO 60 332 332 PRO PRO C . n 
A 1 61 GLY 61 333 333 GLY GLY C . n 
A 1 62 GLY 62 334 334 GLY GLY C . n 
A 1 63 GLY 63 335 335 GLY GLY C . n 
A 1 64 GLN 64 336 336 GLN GLN C . n 
A 1 65 VAL 65 337 337 VAL VAL C . n 
A 1 66 GLU 66 338 338 GLU GLU C . n 
A 1 67 VAL 67 339 339 VAL VAL C . n 
A 1 68 LYS 68 340 340 LYS LYS C . n 
A 1 69 SER 69 341 341 SER SER C . n 
A 1 70 GLU 70 342 342 GLU GLU C . n 
A 1 71 LYS 71 343 343 LYS LYS C . n 
A 1 72 LEU 72 344 344 LEU LEU C . n 
A 1 73 ASP 73 345 345 ASP ASP C . n 
A 1 74 PHE 74 346 346 PHE PHE C . n 
A 1 75 LYS 75 347 347 LYS LYS C . n 
A 1 76 ASP 76 348 348 ASP ASP C . n 
A 1 77 ARG 77 349 349 ARG ARG C . n 
A 1 78 VAL 78 350 350 VAL VAL C . n 
A 1 79 GLN 79 351 351 GLN GLN C . n 
A 1 80 SER 80 352 352 SER SER C . n 
A 1 81 LYS 81 353 353 LYS LYS C . n 
A 1 82 ILE 82 354 354 ILE ILE C . n 
A 1 83 GLY 83 355 355 GLY GLY C . n 
A 1 84 SER 84 356 356 SER SER C . n 
A 1 85 LEU 85 357 357 LEU LEU C . n 
A 1 86 ASP 86 358 358 ASP ASP C . n 
A 1 87 ASN 87 359 359 ASN ASN C . n 
A 1 88 ILE 88 360 360 ILE ILE C . n 
A 1 89 THR 89 361 361 THR THR C . n 
A 1 90 HIS 90 362 362 HIS HIS C . n 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MR8 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9MR8 
_struct.title                        'Structure of D421-Truncated Tau Fibril' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MR8 
_struct_keywords.text            'Tau, amyloid fibrils, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    TAU_HUMAN 
_struct_ref.pdbx_db_accession          P10636 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;GKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQS
KIGSLDNITH
;
_struct_ref.pdbx_align_begin           590 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9MR8 
_struct_ref_seq.pdbx_strand_id                C 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 90 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P10636 
_struct_ref_seq.db_align_beg                  590 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  679 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       273 
_struct_ref_seq.pdbx_auth_seq_align_end       362 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'representative helical assembly' ? 30-meric  30 
2 'helical asymmetric unit'         ? monomeric 1  
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-30)' A 
2 1        A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1  'identity operation'         1_555 x,y,z 1.00000000 0.00000000  0.00000000 0.00000   0.00000000  1.00000000 0.00000000 0.00000 
0.00000000  0.00000000  1.00000000 0.00000   
2  'helical symmetry operation' ?     ?     0.97050600 -0.24107500 0.00000000 56.55110  0.24107500  0.97050600 0.00000000 
-46.80360 -0.00000000 0.00000000  1.00000000 -71.52000 
3  'helical symmetry operation' ?     ?     0.97429100 -0.22529100 0.00000000 52.44140  0.22529100  0.97429100 0.00000000 
-44.12430 -0.00000000 0.00000000  1.00000000 -66.75200 
4  'helical symmetry operation' ?     ?     0.97782000 -0.20944800 0.00000000 48.37580  0.20944800  0.97782000 0.00000000 
-41.37870 -0.00000000 0.00000000  1.00000000 -61.98400 
5  'helical symmetry operation' ?     ?     0.98109100 -0.19354900 0.00000000 44.35540  0.19354900  0.98109100 0.00000000 
-38.56750 -0.00000000 0.00000000  1.00000000 -57.21600 
6  'helical symmetry operation' ?     ?     0.98410300 -0.17760000 0.00000000 40.38100  0.17760000  0.98410300 0.00000000 
-35.69130 -0.00000000 0.00000000  1.00000000 -52.44800 
7  'helical symmetry operation' ?     ?     0.98685600 -0.16160400 0.00000000 36.45390  0.16160400  0.98685600 0.00000000 
-32.75110 -0.00000000 0.00000000  1.00000000 -47.68000 
8  'helical symmetry operation' ?     ?     0.98934900 -0.14556500 0.00000000 32.57500  0.14556500  0.98934900 0.00000000 
-29.74750 -0.00000000 0.00000000  1.00000000 -42.91200 
9  'helical symmetry operation' ?     ?     0.99158100 -0.12948800 0.00000000 28.74540  0.12948800  0.99158100 0.00000000 
-26.68130 -0.00000000 0.00000000  1.00000000 -38.14400 
10 'helical symmetry operation' ?     ?     0.99355200 -0.11337700 0.00000000 24.96600  0.11337700  0.99355200 0.00000000 
-23.55340 -0.00000000 0.00000000  1.00000000 -33.37600 
11 'helical symmetry operation' ?     ?     0.99526100 -0.09723550 0.00000000 21.23790  0.09723550  0.99526100 0.00000000 
-20.36450 -0.00000000 0.00000000  1.00000000 -28.60800 
12 'helical symmetry operation' ?     ?     0.99670900 -0.08106870 0.00000000 17.56210  0.08106870  0.99670900 0.00000000 
-17.11560 -0.00000000 0.00000000  1.00000000 -23.84000 
13 'helical symmetry operation' ?     ?     0.99789300 -0.06488060 0.00000000 13.93950  0.06488060  0.99789300 0.00000000 
-13.80740 -0.00000000 0.00000000  1.00000000 -19.07200 
14 'helical symmetry operation' ?     ?     0.99881500 -0.04867540 0.00000000 10.37100  0.04867540  0.99881500 0.00000000 
-10.44090 -0.00000000 0.00000000  1.00000000 -14.30400 
15 'helical symmetry operation' ?     ?     0.99947300 -0.03245740 0.00000000 6.85766   0.03245740  0.99947300 0.00000000 -7.01684 
-0.00000000 0.00000000  1.00000000 -9.53600  
16 'helical symmetry operation' ?     ?     0.99986800 -0.01623080 0.00000000 3.40035   0.01623080  0.99986800 0.00000000 -3.53625 
-0.00000000 0.00000000  1.00000000 -4.76800  
17 'helical symmetry operation' ?     ?     0.99986800 0.01623080  0.00000000 -3.34251  -0.01623080 0.99986800 0.00000000 3.59097 
0.00000000  -0.00000000 1.00000000 4.76800   
18 'helical symmetry operation' ?     ?     0.99947300 0.03245740  0.00000000 -6.62630  -0.03245740 0.99947300 0.00000000 7.23572 
0.00000000  -0.00000000 1.00000000 9.53600   
19 'helical symmetry operation' ?     ?     0.99881500 0.04867540  0.00000000 -9.85049  -0.04867540 0.99881500 0.00000000 10.93330 
0.00000000  -0.00000000 1.00000000 14.30400  
20 'helical symmetry operation' ?     ?     0.99789300 0.06488060  0.00000000 -13.01420 -0.06488060 0.99789300 0.00000000 14.68270 
0.00000000  -0.00000000 1.00000000 19.07200  
21 'helical symmetry operation' ?     ?     0.99670900 0.08106870  0.00000000 -16.11670 -0.08106870 0.99670900 0.00000000 18.48300 
0.00000000  -0.00000000 1.00000000 23.84000  
22 'helical symmetry operation' ?     ?     0.99526100 0.09723550  0.00000000 -19.15710 -0.09723550 0.99526100 0.00000000 22.33310 
0.00000000  -0.00000000 1.00000000 28.60800  
23 'helical symmetry operation' ?     ?     0.99355200 0.11337700  0.00000000 -22.13460 -0.11337700 0.99355200 0.00000000 26.23210 
0.00000000  -0.00000000 1.00000000 33.37600  
24 'helical symmetry operation' ?     ?     0.99158100 0.12948800  0.00000000 -25.04850 -0.12948800 0.99158100 0.00000000 30.17880 
0.00000000  -0.00000000 1.00000000 38.14400  
25 'helical symmetry operation' ?     ?     0.98934900 0.14556500  0.00000000 -27.89780 -0.14556500 0.98934900 0.00000000 34.17240 
0.00000000  -0.00000000 1.00000000 42.91200  
26 'helical symmetry operation' ?     ?     0.98685600 0.16160400  0.00000000 -30.68200 -0.16160400 0.98685600 0.00000000 38.21170 
0.00000000  -0.00000000 1.00000000 47.68000  
27 'helical symmetry operation' ?     ?     0.98410300 0.17760000  0.00000000 -33.40030 -0.17760000 0.98410300 0.00000000 42.29560 
0.00000000  -0.00000000 1.00000000 52.44800  
28 'helical symmetry operation' ?     ?     0.98109100 0.19354900  0.00000000 -36.05190 -0.19354900 0.98109100 0.00000000 46.42310 
0.00000000  -0.00000000 1.00000000 57.21600  
29 'helical symmetry operation' ?     ?     0.97782000 0.20944800  0.00000000 -38.63620 -0.20944800 0.97782000 0.00000000 50.59310 
0.00000000  -0.00000000 1.00000000 61.98400  
30 'helical symmetry operation' ?     ?     0.97429100 0.22529100  0.00000000 -41.15240 -0.22529100 0.97429100 0.00000000 54.80450 
0.00000000  -0.00000000 1.00000000 66.75200  
# 
_pdbx_entry_details.entry_id                   9MR8 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LYS C 274 ? ? 61.25   144.93 
2 1 LYS C 294 ? ? -147.58 36.27  
3 1 HIS C 299 ? ? 43.38   86.54  
4 1 LYS C 311 ? ? 39.79   47.58  
# 
_pdbx_helical_symmetry.entry_id                  9MR8 
_pdbx_helical_symmetry.number_of_operations      30 
_pdbx_helical_symmetry.rotation_per_n_subunits   -0.93 
_pdbx_helical_symmetry.rise_per_n_subunits       4.768 
_pdbx_helical_symmetry.n_subunits_divisor        1 
_pdbx_helical_symmetry.dyad_axis                 no 
_pdbx_helical_symmetry.circular_symmetry         1 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MR8 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'AB INITIO MODEL' 
# 
_em_3d_reconstruction.entry_id                    9MR8 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               31533 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 CELL 
_em_entity_assembly.name                 'Tau 0N (1-421)' 
_em_entity_assembly.details              'tau construct with truncation at D421' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9MR8 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             200 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9MR8 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9MR8 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ARG N    N N N 1   
ARG CA   C N S 2   
ARG C    C N N 3   
ARG O    O N N 4   
ARG CB   C N N 5   
ARG CG   C N N 6   
ARG CD   C N N 7   
ARG NE   N N N 8   
ARG CZ   C N N 9   
ARG NH1  N N N 10  
ARG NH2  N N N 11  
ARG OXT  O N N 12  
ARG H    H N N 13  
ARG H2   H N N 14  
ARG HA   H N N 15  
ARG HB2  H N N 16  
ARG HB3  H N N 17  
ARG HG2  H N N 18  
ARG HG3  H N N 19  
ARG HD2  H N N 20  
ARG HD3  H N N 21  
ARG HE   H N N 22  
ARG HH11 H N N 23  
ARG HH12 H N N 24  
ARG HH21 H N N 25  
ARG HH22 H N N 26  
ARG HXT  H N N 27  
ASN N    N N N 28  
ASN CA   C N S 29  
ASN C    C N N 30  
ASN O    O N N 31  
ASN CB   C N N 32  
ASN CG   C N N 33  
ASN OD1  O N N 34  
ASN ND2  N N N 35  
ASN OXT  O N N 36  
ASN H    H N N 37  
ASN H2   H N N 38  
ASN HA   H N N 39  
ASN HB2  H N N 40  
ASN HB3  H N N 41  
ASN HD21 H N N 42  
ASN HD22 H N N 43  
ASN HXT  H N N 44  
ASP N    N N N 45  
ASP CA   C N S 46  
ASP C    C N N 47  
ASP O    O N N 48  
ASP CB   C N N 49  
ASP CG   C N N 50  
ASP OD1  O N N 51  
ASP OD2  O N N 52  
ASP OXT  O N N 53  
ASP H    H N N 54  
ASP H2   H N N 55  
ASP HA   H N N 56  
ASP HB2  H N N 57  
ASP HB3  H N N 58  
ASP HD2  H N N 59  
ASP HXT  H N N 60  
CYS N    N N N 61  
CYS CA   C N R 62  
CYS C    C N N 63  
CYS O    O N N 64  
CYS CB   C N N 65  
CYS SG   S N N 66  
CYS OXT  O N N 67  
CYS H    H N N 68  
CYS H2   H N N 69  
CYS HA   H N N 70  
CYS HB2  H N N 71  
CYS HB3  H N N 72  
CYS HG   H N N 73  
CYS HXT  H N N 74  
GLN N    N N N 75  
GLN CA   C N S 76  
GLN C    C N N 77  
GLN O    O N N 78  
GLN CB   C N N 79  
GLN CG   C N N 80  
GLN CD   C N N 81  
GLN OE1  O N N 82  
GLN NE2  N N N 83  
GLN OXT  O N N 84  
GLN H    H N N 85  
GLN H2   H N N 86  
GLN HA   H N N 87  
GLN HB2  H N N 88  
GLN HB3  H N N 89  
GLN HG2  H N N 90  
GLN HG3  H N N 91  
GLN HE21 H N N 92  
GLN HE22 H N N 93  
GLN HXT  H N N 94  
GLU N    N N N 95  
GLU CA   C N S 96  
GLU C    C N N 97  
GLU O    O N N 98  
GLU CB   C N N 99  
GLU CG   C N N 100 
GLU CD   C N N 101 
GLU OE1  O N N 102 
GLU OE2  O N N 103 
GLU OXT  O N N 104 
GLU H    H N N 105 
GLU H2   H N N 106 
GLU HA   H N N 107 
GLU HB2  H N N 108 
GLU HB3  H N N 109 
GLU HG2  H N N 110 
GLU HG3  H N N 111 
GLU HE2  H N N 112 
GLU HXT  H N N 113 
GLY N    N N N 114 
GLY CA   C N N 115 
GLY C    C N N 116 
GLY O    O N N 117 
GLY OXT  O N N 118 
GLY H    H N N 119 
GLY H2   H N N 120 
GLY HA2  H N N 121 
GLY HA3  H N N 122 
GLY HXT  H N N 123 
HIS N    N N N 124 
HIS CA   C N S 125 
HIS C    C N N 126 
HIS O    O N N 127 
HIS CB   C N N 128 
HIS CG   C Y N 129 
HIS ND1  N Y N 130 
HIS CD2  C Y N 131 
HIS CE1  C Y N 132 
HIS NE2  N Y N 133 
HIS OXT  O N N 134 
HIS H    H N N 135 
HIS H2   H N N 136 
HIS HA   H N N 137 
HIS HB2  H N N 138 
HIS HB3  H N N 139 
HIS HD1  H N N 140 
HIS HD2  H N N 141 
HIS HE1  H N N 142 
HIS HE2  H N N 143 
HIS HXT  H N N 144 
ILE N    N N N 145 
ILE CA   C N S 146 
ILE C    C N N 147 
ILE O    O N N 148 
ILE CB   C N S 149 
ILE CG1  C N N 150 
ILE CG2  C N N 151 
ILE CD1  C N N 152 
ILE OXT  O N N 153 
ILE H    H N N 154 
ILE H2   H N N 155 
ILE HA   H N N 156 
ILE HB   H N N 157 
ILE HG12 H N N 158 
ILE HG13 H N N 159 
ILE HG21 H N N 160 
ILE HG22 H N N 161 
ILE HG23 H N N 162 
ILE HD11 H N N 163 
ILE HD12 H N N 164 
ILE HD13 H N N 165 
ILE HXT  H N N 166 
LEU N    N N N 167 
LEU CA   C N S 168 
LEU C    C N N 169 
LEU O    O N N 170 
LEU CB   C N N 171 
LEU CG   C N N 172 
LEU CD1  C N N 173 
LEU CD2  C N N 174 
LEU OXT  O N N 175 
LEU H    H N N 176 
LEU H2   H N N 177 
LEU HA   H N N 178 
LEU HB2  H N N 179 
LEU HB3  H N N 180 
LEU HG   H N N 181 
LEU HD11 H N N 182 
LEU HD12 H N N 183 
LEU HD13 H N N 184 
LEU HD21 H N N 185 
LEU HD22 H N N 186 
LEU HD23 H N N 187 
LEU HXT  H N N 188 
LYS N    N N N 189 
LYS CA   C N S 190 
LYS C    C N N 191 
LYS O    O N N 192 
LYS CB   C N N 193 
LYS CG   C N N 194 
LYS CD   C N N 195 
LYS CE   C N N 196 
LYS NZ   N N N 197 
LYS OXT  O N N 198 
LYS H    H N N 199 
LYS H2   H N N 200 
LYS HA   H N N 201 
LYS HB2  H N N 202 
LYS HB3  H N N 203 
LYS HG2  H N N 204 
LYS HG3  H N N 205 
LYS HD2  H N N 206 
LYS HD3  H N N 207 
LYS HE2  H N N 208 
LYS HE3  H N N 209 
LYS HZ1  H N N 210 
LYS HZ2  H N N 211 
LYS HZ3  H N N 212 
LYS HXT  H N N 213 
PHE N    N N N 214 
PHE CA   C N S 215 
PHE C    C N N 216 
PHE O    O N N 217 
PHE CB   C N N 218 
PHE CG   C Y N 219 
PHE CD1  C Y N 220 
PHE CD2  C Y N 221 
PHE CE1  C Y N 222 
PHE CE2  C Y N 223 
PHE CZ   C Y N 224 
PHE OXT  O N N 225 
PHE H    H N N 226 
PHE H2   H N N 227 
PHE HA   H N N 228 
PHE HB2  H N N 229 
PHE HB3  H N N 230 
PHE HD1  H N N 231 
PHE HD2  H N N 232 
PHE HE1  H N N 233 
PHE HE2  H N N 234 
PHE HZ   H N N 235 
PHE HXT  H N N 236 
PRO N    N N N 237 
PRO CA   C N S 238 
PRO C    C N N 239 
PRO O    O N N 240 
PRO CB   C N N 241 
PRO CG   C N N 242 
PRO CD   C N N 243 
PRO OXT  O N N 244 
PRO H    H N N 245 
PRO HA   H N N 246 
PRO HB2  H N N 247 
PRO HB3  H N N 248 
PRO HG2  H N N 249 
PRO HG3  H N N 250 
PRO HD2  H N N 251 
PRO HD3  H N N 252 
PRO HXT  H N N 253 
SER N    N N N 254 
SER CA   C N S 255 
SER C    C N N 256 
SER O    O N N 257 
SER CB   C N N 258 
SER OG   O N N 259 
SER OXT  O N N 260 
SER H    H N N 261 
SER H2   H N N 262 
SER HA   H N N 263 
SER HB2  H N N 264 
SER HB3  H N N 265 
SER HG   H N N 266 
SER HXT  H N N 267 
THR N    N N N 268 
THR CA   C N S 269 
THR C    C N N 270 
THR O    O N N 271 
THR CB   C N R 272 
THR OG1  O N N 273 
THR CG2  C N N 274 
THR OXT  O N N 275 
THR H    H N N 276 
THR H2   H N N 277 
THR HA   H N N 278 
THR HB   H N N 279 
THR HG1  H N N 280 
THR HG21 H N N 281 
THR HG22 H N N 282 
THR HG23 H N N 283 
THR HXT  H N N 284 
TYR N    N N N 285 
TYR CA   C N S 286 
TYR C    C N N 287 
TYR O    O N N 288 
TYR CB   C N N 289 
TYR CG   C Y N 290 
TYR CD1  C Y N 291 
TYR CD2  C Y N 292 
TYR CE1  C Y N 293 
TYR CE2  C Y N 294 
TYR CZ   C Y N 295 
TYR OH   O N N 296 
TYR OXT  O N N 297 
TYR H    H N N 298 
TYR H2   H N N 299 
TYR HA   H N N 300 
TYR HB2  H N N 301 
TYR HB3  H N N 302 
TYR HD1  H N N 303 
TYR HD2  H N N 304 
TYR HE1  H N N 305 
TYR HE2  H N N 306 
TYR HH   H N N 307 
TYR HXT  H N N 308 
VAL N    N N N 309 
VAL CA   C N S 310 
VAL C    C N N 311 
VAL O    O N N 312 
VAL CB   C N N 313 
VAL CG1  C N N 314 
VAL CG2  C N N 315 
VAL OXT  O N N 316 
VAL H    H N N 317 
VAL H2   H N N 318 
VAL HA   H N N 319 
VAL HB   H N N 320 
VAL HG11 H N N 321 
VAL HG12 H N N 322 
VAL HG13 H N N 323 
VAL HG21 H N N 324 
VAL HG22 H N N 325 
VAL HG23 H N N 326 
VAL HXT  H N N 327 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ARG N   CA   sing N N 1   
ARG N   H    sing N N 2   
ARG N   H2   sing N N 3   
ARG CA  C    sing N N 4   
ARG CA  CB   sing N N 5   
ARG CA  HA   sing N N 6   
ARG C   O    doub N N 7   
ARG C   OXT  sing N N 8   
ARG CB  CG   sing N N 9   
ARG CB  HB2  sing N N 10  
ARG CB  HB3  sing N N 11  
ARG CG  CD   sing N N 12  
ARG CG  HG2  sing N N 13  
ARG CG  HG3  sing N N 14  
ARG CD  NE   sing N N 15  
ARG CD  HD2  sing N N 16  
ARG CD  HD3  sing N N 17  
ARG NE  CZ   sing N N 18  
ARG NE  HE   sing N N 19  
ARG CZ  NH1  sing N N 20  
ARG CZ  NH2  doub N N 21  
ARG NH1 HH11 sing N N 22  
ARG NH1 HH12 sing N N 23  
ARG NH2 HH21 sing N N 24  
ARG NH2 HH22 sing N N 25  
ARG OXT HXT  sing N N 26  
ASN N   CA   sing N N 27  
ASN N   H    sing N N 28  
ASN N   H2   sing N N 29  
ASN CA  C    sing N N 30  
ASN CA  CB   sing N N 31  
ASN CA  HA   sing N N 32  
ASN C   O    doub N N 33  
ASN C   OXT  sing N N 34  
ASN CB  CG   sing N N 35  
ASN CB  HB2  sing N N 36  
ASN CB  HB3  sing N N 37  
ASN CG  OD1  doub N N 38  
ASN CG  ND2  sing N N 39  
ASN ND2 HD21 sing N N 40  
ASN ND2 HD22 sing N N 41  
ASN OXT HXT  sing N N 42  
ASP N   CA   sing N N 43  
ASP N   H    sing N N 44  
ASP N   H2   sing N N 45  
ASP CA  C    sing N N 46  
ASP CA  CB   sing N N 47  
ASP CA  HA   sing N N 48  
ASP C   O    doub N N 49  
ASP C   OXT  sing N N 50  
ASP CB  CG   sing N N 51  
ASP CB  HB2  sing N N 52  
ASP CB  HB3  sing N N 53  
ASP CG  OD1  doub N N 54  
ASP CG  OD2  sing N N 55  
ASP OD2 HD2  sing N N 56  
ASP OXT HXT  sing N N 57  
CYS N   CA   sing N N 58  
CYS N   H    sing N N 59  
CYS N   H2   sing N N 60  
CYS CA  C    sing N N 61  
CYS CA  CB   sing N N 62  
CYS CA  HA   sing N N 63  
CYS C   O    doub N N 64  
CYS C   OXT  sing N N 65  
CYS CB  SG   sing N N 66  
CYS CB  HB2  sing N N 67  
CYS CB  HB3  sing N N 68  
CYS SG  HG   sing N N 69  
CYS OXT HXT  sing N N 70  
GLN N   CA   sing N N 71  
GLN N   H    sing N N 72  
GLN N   H2   sing N N 73  
GLN CA  C    sing N N 74  
GLN CA  CB   sing N N 75  
GLN CA  HA   sing N N 76  
GLN C   O    doub N N 77  
GLN C   OXT  sing N N 78  
GLN CB  CG   sing N N 79  
GLN CB  HB2  sing N N 80  
GLN CB  HB3  sing N N 81  
GLN CG  CD   sing N N 82  
GLN CG  HG2  sing N N 83  
GLN CG  HG3  sing N N 84  
GLN CD  OE1  doub N N 85  
GLN CD  NE2  sing N N 86  
GLN NE2 HE21 sing N N 87  
GLN NE2 HE22 sing N N 88  
GLN OXT HXT  sing N N 89  
GLU N   CA   sing N N 90  
GLU N   H    sing N N 91  
GLU N   H2   sing N N 92  
GLU CA  C    sing N N 93  
GLU CA  CB   sing N N 94  
GLU CA  HA   sing N N 95  
GLU C   O    doub N N 96  
GLU C   OXT  sing N N 97  
GLU CB  CG   sing N N 98  
GLU CB  HB2  sing N N 99  
GLU CB  HB3  sing N N 100 
GLU CG  CD   sing N N 101 
GLU CG  HG2  sing N N 102 
GLU CG  HG3  sing N N 103 
GLU CD  OE1  doub N N 104 
GLU CD  OE2  sing N N 105 
GLU OE2 HE2  sing N N 106 
GLU OXT HXT  sing N N 107 
GLY N   CA   sing N N 108 
GLY N   H    sing N N 109 
GLY N   H2   sing N N 110 
GLY CA  C    sing N N 111 
GLY CA  HA2  sing N N 112 
GLY CA  HA3  sing N N 113 
GLY C   O    doub N N 114 
GLY C   OXT  sing N N 115 
GLY OXT HXT  sing N N 116 
HIS N   CA   sing N N 117 
HIS N   H    sing N N 118 
HIS N   H2   sing N N 119 
HIS CA  C    sing N N 120 
HIS CA  CB   sing N N 121 
HIS CA  HA   sing N N 122 
HIS C   O    doub N N 123 
HIS C   OXT  sing N N 124 
HIS CB  CG   sing N N 125 
HIS CB  HB2  sing N N 126 
HIS CB  HB3  sing N N 127 
HIS CG  ND1  sing Y N 128 
HIS CG  CD2  doub Y N 129 
HIS ND1 CE1  doub Y N 130 
HIS ND1 HD1  sing N N 131 
HIS CD2 NE2  sing Y N 132 
HIS CD2 HD2  sing N N 133 
HIS CE1 NE2  sing Y N 134 
HIS CE1 HE1  sing N N 135 
HIS NE2 HE2  sing N N 136 
HIS OXT HXT  sing N N 137 
ILE N   CA   sing N N 138 
ILE N   H    sing N N 139 
ILE N   H2   sing N N 140 
ILE CA  C    sing N N 141 
ILE CA  CB   sing N N 142 
ILE CA  HA   sing N N 143 
ILE C   O    doub N N 144 
ILE C   OXT  sing N N 145 
ILE CB  CG1  sing N N 146 
ILE CB  CG2  sing N N 147 
ILE CB  HB   sing N N 148 
ILE CG1 CD1  sing N N 149 
ILE CG1 HG12 sing N N 150 
ILE CG1 HG13 sing N N 151 
ILE CG2 HG21 sing N N 152 
ILE CG2 HG22 sing N N 153 
ILE CG2 HG23 sing N N 154 
ILE CD1 HD11 sing N N 155 
ILE CD1 HD12 sing N N 156 
ILE CD1 HD13 sing N N 157 
ILE OXT HXT  sing N N 158 
LEU N   CA   sing N N 159 
LEU N   H    sing N N 160 
LEU N   H2   sing N N 161 
LEU CA  C    sing N N 162 
LEU CA  CB   sing N N 163 
LEU CA  HA   sing N N 164 
LEU C   O    doub N N 165 
LEU C   OXT  sing N N 166 
LEU CB  CG   sing N N 167 
LEU CB  HB2  sing N N 168 
LEU CB  HB3  sing N N 169 
LEU CG  CD1  sing N N 170 
LEU CG  CD2  sing N N 171 
LEU CG  HG   sing N N 172 
LEU CD1 HD11 sing N N 173 
LEU CD1 HD12 sing N N 174 
LEU CD1 HD13 sing N N 175 
LEU CD2 HD21 sing N N 176 
LEU CD2 HD22 sing N N 177 
LEU CD2 HD23 sing N N 178 
LEU OXT HXT  sing N N 179 
LYS N   CA   sing N N 180 
LYS N   H    sing N N 181 
LYS N   H2   sing N N 182 
LYS CA  C    sing N N 183 
LYS CA  CB   sing N N 184 
LYS CA  HA   sing N N 185 
LYS C   O    doub N N 186 
LYS C   OXT  sing N N 187 
LYS CB  CG   sing N N 188 
LYS CB  HB2  sing N N 189 
LYS CB  HB3  sing N N 190 
LYS CG  CD   sing N N 191 
LYS CG  HG2  sing N N 192 
LYS CG  HG3  sing N N 193 
LYS CD  CE   sing N N 194 
LYS CD  HD2  sing N N 195 
LYS CD  HD3  sing N N 196 
LYS CE  NZ   sing N N 197 
LYS CE  HE2  sing N N 198 
LYS CE  HE3  sing N N 199 
LYS NZ  HZ1  sing N N 200 
LYS NZ  HZ2  sing N N 201 
LYS NZ  HZ3  sing N N 202 
LYS OXT HXT  sing N N 203 
PHE N   CA   sing N N 204 
PHE N   H    sing N N 205 
PHE N   H2   sing N N 206 
PHE CA  C    sing N N 207 
PHE CA  CB   sing N N 208 
PHE CA  HA   sing N N 209 
PHE C   O    doub N N 210 
PHE C   OXT  sing N N 211 
PHE CB  CG   sing N N 212 
PHE CB  HB2  sing N N 213 
PHE CB  HB3  sing N N 214 
PHE CG  CD1  doub Y N 215 
PHE CG  CD2  sing Y N 216 
PHE CD1 CE1  sing Y N 217 
PHE CD1 HD1  sing N N 218 
PHE CD2 CE2  doub Y N 219 
PHE CD2 HD2  sing N N 220 
PHE CE1 CZ   doub Y N 221 
PHE CE1 HE1  sing N N 222 
PHE CE2 CZ   sing Y N 223 
PHE CE2 HE2  sing N N 224 
PHE CZ  HZ   sing N N 225 
PHE OXT HXT  sing N N 226 
PRO N   CA   sing N N 227 
PRO N   CD   sing N N 228 
PRO N   H    sing N N 229 
PRO CA  C    sing N N 230 
PRO CA  CB   sing N N 231 
PRO CA  HA   sing N N 232 
PRO C   O    doub N N 233 
PRO C   OXT  sing N N 234 
PRO CB  CG   sing N N 235 
PRO CB  HB2  sing N N 236 
PRO CB  HB3  sing N N 237 
PRO CG  CD   sing N N 238 
PRO CG  HG2  sing N N 239 
PRO CG  HG3  sing N N 240 
PRO CD  HD2  sing N N 241 
PRO CD  HD3  sing N N 242 
PRO OXT HXT  sing N N 243 
SER N   CA   sing N N 244 
SER N   H    sing N N 245 
SER N   H2   sing N N 246 
SER CA  C    sing N N 247 
SER CA  CB   sing N N 248 
SER CA  HA   sing N N 249 
SER C   O    doub N N 250 
SER C   OXT  sing N N 251 
SER CB  OG   sing N N 252 
SER CB  HB2  sing N N 253 
SER CB  HB3  sing N N 254 
SER OG  HG   sing N N 255 
SER OXT HXT  sing N N 256 
THR N   CA   sing N N 257 
THR N   H    sing N N 258 
THR N   H2   sing N N 259 
THR CA  C    sing N N 260 
THR CA  CB   sing N N 261 
THR CA  HA   sing N N 262 
THR C   O    doub N N 263 
THR C   OXT  sing N N 264 
THR CB  OG1  sing N N 265 
THR CB  CG2  sing N N 266 
THR CB  HB   sing N N 267 
THR OG1 HG1  sing N N 268 
THR CG2 HG21 sing N N 269 
THR CG2 HG22 sing N N 270 
THR CG2 HG23 sing N N 271 
THR OXT HXT  sing N N 272 
TYR N   CA   sing N N 273 
TYR N   H    sing N N 274 
TYR N   H2   sing N N 275 
TYR CA  C    sing N N 276 
TYR CA  CB   sing N N 277 
TYR CA  HA   sing N N 278 
TYR C   O    doub N N 279 
TYR C   OXT  sing N N 280 
TYR CB  CG   sing N N 281 
TYR CB  HB2  sing N N 282 
TYR CB  HB3  sing N N 283 
TYR CG  CD1  doub Y N 284 
TYR CG  CD2  sing Y N 285 
TYR CD1 CE1  sing Y N 286 
TYR CD1 HD1  sing N N 287 
TYR CD2 CE2  doub Y N 288 
TYR CD2 HD2  sing N N 289 
TYR CE1 CZ   doub Y N 290 
TYR CE1 HE1  sing N N 291 
TYR CE2 CZ   sing Y N 292 
TYR CE2 HE2  sing N N 293 
TYR CZ  OH   sing N N 294 
TYR OH  HH   sing N N 295 
TYR OXT HXT  sing N N 296 
VAL N   CA   sing N N 297 
VAL N   H    sing N N 298 
VAL N   H2   sing N N 299 
VAL CA  C    sing N N 300 
VAL CA  CB   sing N N 301 
VAL CA  HA   sing N N 302 
VAL C   O    doub N N 303 
VAL C   OXT  sing N N 304 
VAL CB  CG1  sing N N 305 
VAL CB  CG2  sing N N 306 
VAL CB  HB   sing N N 307 
VAL CG1 HG11 sing N N 308 
VAL CG1 HG12 sing N N 309 
VAL CG1 HG13 sing N N 310 
VAL CG2 HG21 sing N N 311 
VAL CG2 HG22 sing N N 312 
VAL CG2 HG23 sing N N 313 
VAL OXT HXT  sing N N 314 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-01-07 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MR8 
_em_admin.last_update        2025-03-19 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Structure of D421-Truncated Tau Fibril' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C1 
_em_helical_entity.angular_rotation_per_subunit   -0.93 
_em_helical_entity.axial_rise_per_subunit         4.768 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         1.04756 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? 1 ? ? ? 
OTHER                           ? 8  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 9  ? 1 ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Institute on Aging (NIH/NIA)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           AG059661 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9MR8 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N    . GLY A 1 1  ? 186.465 246.549 144.332 1.00 30.00 ? 273 GLY C N    1 
ATOM 2    C CA   . GLY A 1 1  ? 187.424 247.271 143.489 1.00 30.00 ? 273 GLY C CA   1 
ATOM 3    C C    . GLY A 1 1  ? 188.818 246.720 143.680 1.00 30.00 ? 273 GLY C C    1 
ATOM 4    O O    . GLY A 1 1  ? 189.272 246.607 144.813 1.00 30.00 ? 273 GLY C O    1 
ATOM 5    H H1   . GLY A 1 1  ? 185.537 246.914 144.190 1.00 30.00 ? 273 GLY C H1   1 
ATOM 6    H H2   . GLY A 1 1  ? 186.716 246.656 145.301 1.00 30.00 ? 273 GLY C H2   1 
ATOM 7    H H3   . GLY A 1 1  ? 186.472 245.569 144.102 1.00 30.00 ? 273 GLY C H3   1 
ATOM 8    H HA2  . GLY A 1 1  ? 187.138 247.173 142.444 1.00 30.00 ? 273 GLY C HA2  1 
ATOM 9    H HA3  . GLY A 1 1  ? 187.423 248.322 143.763 1.00 30.00 ? 273 GLY C HA3  1 
ATOM 10   N N    . LYS A 1 2  ? 189.507 246.424 142.575 1.00 30.00 ? 274 LYS C N    1 
ATOM 11   C CA   . LYS A 1 2  ? 190.855 245.824 142.474 1.00 30.00 ? 274 LYS C CA   1 
ATOM 12   C C    . LYS A 1 2  ? 191.004 244.422 143.082 1.00 30.00 ? 274 LYS C C    1 
ATOM 13   O O    . LYS A 1 2  ? 190.447 244.115 144.127 1.00 30.00 ? 274 LYS C O    1 
ATOM 14   C CB   . LYS A 1 2  ? 191.940 246.818 142.959 1.00 30.00 ? 274 LYS C CB   1 
ATOM 15   C CG   . LYS A 1 2  ? 193.364 246.294 142.715 1.00 30.00 ? 274 LYS C CG   1 
ATOM 16   C CD   . LYS A 1 2  ? 194.475 247.312 142.996 1.00 30.00 ? 274 LYS C CD   1 
ATOM 17   C CE   . LYS A 1 2  ? 195.811 246.585 142.807 1.00 30.00 ? 274 LYS C CE   1 
ATOM 18   N NZ   . LYS A 1 2  ? 196.981 247.479 142.910 1.00 30.00 ? 274 LYS C NZ   1 
ATOM 19   H H    . LYS A 1 2  ? 189.045 246.625 141.704 1.00 30.00 ? 274 LYS C H    1 
ATOM 20   H HA   . LYS A 1 2  ? 191.037 245.691 141.409 1.00 30.00 ? 274 LYS C HA   1 
ATOM 21   H HB2  . LYS A 1 2  ? 191.816 247.756 142.421 1.00 30.00 ? 274 LYS C HB2  1 
ATOM 22   H HB3  . LYS A 1 2  ? 191.817 247.014 144.022 1.00 30.00 ? 274 LYS C HB3  1 
ATOM 23   H HG2  . LYS A 1 2  ? 193.528 245.438 143.365 1.00 30.00 ? 274 LYS C HG2  1 
ATOM 24   H HG3  . LYS A 1 2  ? 193.447 245.978 141.678 1.00 30.00 ? 274 LYS C HG3  1 
ATOM 25   H HD2  . LYS A 1 2  ? 194.397 248.141 142.298 1.00 30.00 ? 274 LYS C HD2  1 
ATOM 26   H HD3  . LYS A 1 2  ? 194.388 247.680 144.016 1.00 30.00 ? 274 LYS C HD3  1 
ATOM 27   H HE2  . LYS A 1 2  ? 195.888 245.805 143.557 1.00 30.00 ? 274 LYS C HE2  1 
ATOM 28   H HE3  . LYS A 1 2  ? 195.802 246.103 141.837 1.00 30.00 ? 274 LYS C HE3  1 
ATOM 29   H HZ1  . LYS A 1 2  ? 196.950 248.193 142.205 1.00 30.00 ? 274 LYS C HZ1  1 
ATOM 30   H HZ2  . LYS A 1 2  ? 197.019 247.926 143.810 1.00 30.00 ? 274 LYS C HZ2  1 
ATOM 31   H HZ3  . LYS A 1 2  ? 197.833 246.955 142.790 1.00 30.00 ? 274 LYS C HZ3  1 
ATOM 32   N N    . VAL A 1 3  ? 191.837 243.612 142.437 1.00 30.00 ? 275 VAL C N    1 
ATOM 33   C CA   . VAL A 1 3  ? 192.574 242.470 143.014 1.00 30.00 ? 275 VAL C CA   1 
ATOM 34   C C    . VAL A 1 3  ? 193.992 242.488 142.426 1.00 30.00 ? 275 VAL C C    1 
ATOM 35   O O    . VAL A 1 3  ? 194.194 243.013 141.333 1.00 30.00 ? 275 VAL C O    1 
ATOM 36   C CB   . VAL A 1 3  ? 191.856 241.126 142.759 1.00 30.00 ? 275 VAL C CB   1 
ATOM 37   C CG1  . VAL A 1 3  ? 192.624 239.917 143.307 1.00 30.00 ? 275 VAL C CG1  1 
ATOM 38   C CG2  . VAL A 1 3  ? 190.462 241.082 143.395 1.00 30.00 ? 275 VAL C CG2  1 
ATOM 39   H H    . VAL A 1 3  ? 192.197 243.947 141.557 1.00 30.00 ? 275 VAL C H    1 
ATOM 40   H HA   . VAL A 1 3  ? 192.663 242.603 144.091 1.00 30.00 ? 275 VAL C HA   1 
ATOM 41   H HB   . VAL A 1 3  ? 191.743 240.990 141.686 1.00 30.00 ? 275 VAL C HB   1 
ATOM 42   H HG11 . VAL A 1 3  ? 192.037 239.013 143.178 1.00 30.00 ? 275 VAL C HG11 1 
ATOM 43   H HG12 . VAL A 1 3  ? 193.549 239.774 142.758 1.00 30.00 ? 275 VAL C HG12 1 
ATOM 44   H HG13 . VAL A 1 3  ? 192.833 240.053 144.362 1.00 30.00 ? 275 VAL C HG13 1 
ATOM 45   H HG21 . VAL A 1 3  ? 189.811 241.817 142.924 1.00 30.00 ? 275 VAL C HG21 1 
ATOM 46   H HG22 . VAL A 1 3  ? 190.014 240.102 143.252 1.00 30.00 ? 275 VAL C HG22 1 
ATOM 47   H HG23 . VAL A 1 3  ? 190.534 241.298 144.458 1.00 30.00 ? 275 VAL C HG23 1 
ATOM 48   N N    . GLN A 1 4  ? 194.990 241.940 143.117 1.00 30.00 ? 276 GLN C N    1 
ATOM 49   C CA   . GLN A 1 4  ? 196.322 241.722 142.559 1.00 30.00 ? 276 GLN C CA   1 
ATOM 50   C C    . GLN A 1 4  ? 196.942 240.455 143.137 1.00 30.00 ? 276 GLN C C    1 
ATOM 51   O O    . GLN A 1 4  ? 196.685 240.119 144.285 1.00 30.00 ? 276 GLN C O    1 
ATOM 52   C CB   . GLN A 1 4  ? 197.179 242.967 142.812 1.00 30.00 ? 276 GLN C CB   1 
ATOM 53   C CG   . GLN A 1 4  ? 198.657 242.819 142.424 1.00 30.00 ? 276 GLN C CG   1 
ATOM 54   C CD   . GLN A 1 4  ? 199.435 244.129 142.510 1.00 30.00 ? 276 GLN C CD   1 
ATOM 55   O OE1  . GLN A 1 4  ? 198.885 245.218 142.618 1.00 30.00 ? 276 GLN C OE1  1 
ATOM 56   N NE2  . GLN A 1 4  ? 200.746 244.078 142.483 1.00 30.00 ? 276 GLN C NE2  1 
ATOM 57   H H    . GLN A 1 4  ? 194.794 241.530 144.017 1.00 30.00 ? 276 GLN C H    1 
ATOM 58   H HA   . GLN A 1 4  ? 196.244 241.575 141.483 1.00 30.00 ? 276 GLN C HA   1 
ATOM 59   H HB2  . GLN A 1 4  ? 196.754 243.784 142.236 1.00 30.00 ? 276 GLN C HB2  1 
ATOM 60   H HB3  . GLN A 1 4  ? 197.118 243.225 143.864 1.00 30.00 ? 276 GLN C HB3  1 
ATOM 61   H HG2  . GLN A 1 4  ? 199.126 242.097 143.087 1.00 30.00 ? 276 GLN C HG2  1 
ATOM 62   H HG3  . GLN A 1 4  ? 198.735 242.451 141.404 1.00 30.00 ? 276 GLN C HG3  1 
ATOM 63   H HE21 . GLN A 1 4  ? 201.258 244.946 142.548 1.00 30.00 ? 276 GLN C HE21 1 
ATOM 64   H HE22 . GLN A 1 4  ? 201.221 243.193 142.399 1.00 30.00 ? 276 GLN C HE22 1 
ATOM 65   N N    . ILE A 1 5  ? 197.785 239.769 142.364 1.00 30.00 ? 277 ILE C N    1 
ATOM 66   C CA   . ILE A 1 5  ? 198.692 238.682 142.789 1.00 30.00 ? 277 ILE C CA   1 
ATOM 67   C C    . ILE A 1 5  ? 200.021 238.893 142.044 1.00 30.00 ? 277 ILE C C    1 
ATOM 68   O O    . ILE A 1 5  ? 199.984 239.314 140.887 1.00 30.00 ? 277 ILE C O    1 
ATOM 69   C CB   . ILE A 1 5  ? 198.088 237.279 142.491 1.00 30.00 ? 277 ILE C CB   1 
ATOM 70   C CG1  . ILE A 1 5  ? 196.782 236.998 143.265 1.00 30.00 ? 277 ILE C CG1  1 
ATOM 71   C CG2  . ILE A 1 5  ? 199.075 236.164 142.854 1.00 30.00 ? 277 ILE C CG2  1 
ATOM 72   C CD1  . ILE A 1 5  ? 195.515 237.343 142.479 1.00 30.00 ? 277 ILE C CD1  1 
ATOM 73   H H    . ILE A 1 5  ? 197.923 240.098 141.421 1.00 30.00 ? 277 ILE C H    1 
ATOM 74   H HA   . ILE A 1 5  ? 198.880 238.767 143.859 1.00 30.00 ? 277 ILE C HA   1 
ATOM 75   H HB   . ILE A 1 5  ? 197.885 237.207 141.424 1.00 30.00 ? 277 ILE C HB   1 
ATOM 76   H HG12 . ILE A 1 5  ? 196.706 235.939 143.502 1.00 30.00 ? 277 ILE C HG12 1 
ATOM 77   H HG13 . ILE A 1 5  ? 196.792 237.531 144.212 1.00 30.00 ? 277 ILE C HG13 1 
ATOM 78   H HG21 . ILE A 1 5  ? 198.627 235.191 142.662 1.00 30.00 ? 277 ILE C HG21 1 
ATOM 79   H HG22 . ILE A 1 5  ? 199.342 236.231 143.906 1.00 30.00 ? 277 ILE C HG22 1 
ATOM 80   H HG23 . ILE A 1 5  ? 199.971 236.229 142.241 1.00 30.00 ? 277 ILE C HG23 1 
ATOM 81   H HD11 . ILE A 1 5  ? 194.650 237.173 143.108 1.00 30.00 ? 277 ILE C HD11 1 
ATOM 82   H HD12 . ILE A 1 5  ? 195.443 236.702 141.607 1.00 30.00 ? 277 ILE C HD12 1 
ATOM 83   H HD13 . ILE A 1 5  ? 195.518 238.378 142.155 1.00 30.00 ? 277 ILE C HD13 1 
ATOM 84   N N    . ILE A 1 6  ? 201.176 238.599 142.649 1.00 30.00 ? 278 ILE C N    1 
ATOM 85   C CA   . ILE A 1 6  ? 202.470 238.635 141.946 1.00 30.00 ? 278 ILE C CA   1 
ATOM 86   C C    . ILE A 1 6  ? 203.312 237.374 142.169 1.00 30.00 ? 278 ILE C C    1 
ATOM 87   O O    . ILE A 1 6  ? 202.913 236.467 142.890 1.00 30.00 ? 278 ILE C O    1 
ATOM 88   C CB   . ILE A 1 6  ? 203.259 239.948 142.161 1.00 30.00 ? 278 ILE C CB   1 
ATOM 89   C CG1  . ILE A 1 6  ? 204.251 239.958 143.343 1.00 30.00 ? 278 ILE C CG1  1 
ATOM 90   C CG2  . ILE A 1 6  ? 202.363 241.196 142.217 1.00 30.00 ? 278 ILE C CG2  1 
ATOM 91   C CD1  . ILE A 1 6  ? 205.543 240.687 142.960 1.00 30.00 ? 278 ILE C CD1  1 
ATOM 92   H H    . ILE A 1 6  ? 201.154 238.234 143.588 1.00 30.00 ? 278 ILE C H    1 
ATOM 93   H HA   . ILE A 1 6  ? 202.257 238.618 140.878 1.00 30.00 ? 278 ILE C HA   1 
ATOM 94   H HB   . ILE A 1 6  ? 203.857 240.059 141.259 1.00 30.00 ? 278 ILE C HB   1 
ATOM 95   H HG12 . ILE A 1 6  ? 203.795 240.449 144.201 1.00 30.00 ? 278 ILE C HG12 1 
ATOM 96   H HG13 . ILE A 1 6  ? 204.530 238.954 143.655 1.00 30.00 ? 278 ILE C HG13 1 
ATOM 97   H HG21 . ILE A 1 6  ? 202.987 242.088 142.244 1.00 30.00 ? 278 ILE C HG21 1 
ATOM 98   H HG22 . ILE A 1 6  ? 201.738 241.175 143.107 1.00 30.00 ? 278 ILE C HG22 1 
ATOM 99   H HG23 . ILE A 1 6  ? 201.741 241.235 141.325 1.00 30.00 ? 278 ILE C HG23 1 
ATOM 100  H HD11 . ILE A 1 6  ? 206.046 240.164 142.154 1.00 30.00 ? 278 ILE C HD11 1 
ATOM 101  H HD12 . ILE A 1 6  ? 206.204 240.721 143.819 1.00 30.00 ? 278 ILE C HD12 1 
ATOM 102  H HD13 . ILE A 1 6  ? 205.327 241.700 142.644 1.00 30.00 ? 278 ILE C HD13 1 
ATOM 103  N N    . ASN A 1 7  ? 204.462 237.294 141.500 1.00 30.00 ? 279 ASN C N    1 
ATOM 104  C CA   . ASN A 1 7  ? 205.505 236.277 141.695 1.00 30.00 ? 279 ASN C CA   1 
ATOM 105  C C    . ASN A 1 7  ? 206.892 236.840 141.321 1.00 30.00 ? 279 ASN C C    1 
ATOM 106  O O    . ASN A 1 7  ? 206.991 237.740 140.490 1.00 30.00 ? 279 ASN C O    1 
ATOM 107  C CB   . ASN A 1 7  ? 205.191 235.032 140.836 1.00 30.00 ? 279 ASN C CB   1 
ATOM 108  C CG   . ASN A 1 7  ? 204.898 233.799 141.657 1.00 30.00 ? 279 ASN C CG   1 
ATOM 109  O OD1  . ASN A 1 7  ? 205.668 232.850 141.707 1.00 30.00 ? 279 ASN C OD1  1 
ATOM 110  N ND2  . ASN A 1 7  ? 203.778 233.786 142.327 1.00 30.00 ? 279 ASN C ND2  1 
ATOM 111  H H    . ASN A 1 7  ? 204.696 238.057 140.885 1.00 30.00 ? 279 ASN C H    1 
ATOM 112  H HA   . ASN A 1 7  ? 205.534 235.997 142.748 1.00 30.00 ? 279 ASN C HA   1 
ATOM 113  H HB2  . ASN A 1 7  ? 204.337 235.220 140.188 1.00 30.00 ? 279 ASN C HB2  1 
ATOM 114  H HB3  . ASN A 1 7  ? 206.035 234.805 140.186 1.00 30.00 ? 279 ASN C HB3  1 
ATOM 115  H HD21 . ASN A 1 7  ? 203.563 232.978 142.889 1.00 30.00 ? 279 ASN C HD21 1 
ATOM 116  H HD22 . ASN A 1 7  ? 203.217 234.621 142.368 1.00 30.00 ? 279 ASN C HD22 1 
ATOM 117  N N    . LYS A 1 8  ? 207.962 236.262 141.863 1.00 30.00 ? 280 LYS C N    1 
ATOM 118  C CA   . LYS A 1 8  ? 209.302 236.278 141.269 1.00 30.00 ? 280 LYS C CA   1 
ATOM 119  C C    . LYS A 1 8  ? 210.112 235.103 141.793 1.00 30.00 ? 280 LYS C C    1 
ATOM 120  O O    . LYS A 1 8  ? 209.883 234.665 142.915 1.00 30.00 ? 280 LYS C O    1 
ATOM 121  C CB   . LYS A 1 8  ? 210.006 237.611 141.560 1.00 30.00 ? 280 LYS C CB   1 
ATOM 122  C CG   . LYS A 1 8  ? 211.239 237.844 140.665 1.00 30.00 ? 280 LYS C CG   1 
ATOM 123  C CD   . LYS A 1 8  ? 212.591 237.714 141.380 1.00 30.00 ? 280 LYS C CD   1 
ATOM 124  C CE   . LYS A 1 8  ? 212.891 238.921 142.269 1.00 30.00 ? 280 LYS C CE   1 
ATOM 125  N NZ   . LYS A 1 8  ? 213.164 240.141 141.482 1.00 30.00 ? 280 LYS C NZ   1 
ATOM 126  H H    . LYS A 1 8  ? 207.801 235.586 142.593 1.00 30.00 ? 280 LYS C H    1 
ATOM 127  H HA   . LYS A 1 8  ? 209.200 236.166 140.191 1.00 30.00 ? 280 LYS C HA   1 
ATOM 128  H HB2  . LYS A 1 8  ? 209.315 238.426 141.367 1.00 30.00 ? 280 LYS C HB2  1 
ATOM 129  H HB3  . LYS A 1 8  ? 210.276 237.659 142.611 1.00 30.00 ? 280 LYS C HB3  1 
ATOM 130  H HG2  . LYS A 1 8  ? 211.219 237.148 139.830 1.00 30.00 ? 280 LYS C HG2  1 
ATOM 131  H HG3  . LYS A 1 8  ? 211.167 238.838 140.230 1.00 30.00 ? 280 LYS C HG3  1 
ATOM 132  H HD2  . LYS A 1 8  ? 212.593 236.814 141.990 1.00 30.00 ? 280 LYS C HD2  1 
ATOM 133  H HD3  . LYS A 1 8  ? 213.376 237.615 140.632 1.00 30.00 ? 280 LYS C HD3  1 
ATOM 134  H HE2  . LYS A 1 8  ? 212.048 239.076 142.935 1.00 30.00 ? 280 LYS C HE2  1 
ATOM 135  H HE3  . LYS A 1 8  ? 213.759 238.698 142.883 1.00 30.00 ? 280 LYS C HE3  1 
ATOM 136  H HZ1  . LYS A 1 8  ? 212.373 240.407 140.939 1.00 30.00 ? 280 LYS C HZ1  1 
ATOM 137  H HZ2  . LYS A 1 8  ? 213.391 240.911 142.076 1.00 30.00 ? 280 LYS C HZ2  1 
ATOM 138  H HZ3  . LYS A 1 8  ? 213.932 240.009 140.862 1.00 30.00 ? 280 LYS C HZ3  1 
ATOM 139  N N    . LYS A 1 9  ? 211.075 234.617 141.016 1.00 30.00 ? 281 LYS C N    1 
ATOM 140  C CA   . LYS A 1 9  ? 212.027 233.553 141.384 1.00 30.00 ? 281 LYS C CA   1 
ATOM 141  C C    . LYS A 1 9  ? 213.400 233.816 140.761 1.00 30.00 ? 281 LYS C C    1 
ATOM 142  O O    . LYS A 1 9  ? 213.514 234.544 139.776 1.00 30.00 ? 281 LYS C O    1 
ATOM 143  C CB   . LYS A 1 9  ? 211.493 232.170 140.951 1.00 30.00 ? 281 LYS C CB   1 
ATOM 144  C CG   . LYS A 1 9  ? 210.217 231.719 141.678 1.00 30.00 ? 281 LYS C CG   1 
ATOM 145  C CD   . LYS A 1 9  ? 209.876 230.260 141.344 1.00 30.00 ? 281 LYS C CD   1 
ATOM 146  C CE   . LYS A 1 9  ? 208.653 229.729 142.109 1.00 30.00 ? 281 LYS C CE   1 
ATOM 147  N NZ   . LYS A 1 9  ? 207.371 230.339 141.677 1.00 30.00 ? 281 LYS C NZ   1 
ATOM 148  H H    . LYS A 1 9  ? 211.193 235.046 140.113 1.00 30.00 ? 281 LYS C H    1 
ATOM 149  H HA   . LYS A 1 9  ? 212.165 233.542 142.464 1.00 30.00 ? 281 LYS C HA   1 
ATOM 150  H HB2  . LYS A 1 9  ? 211.303 232.175 139.880 1.00 30.00 ? 281 LYS C HB2  1 
ATOM 151  H HB3  . LYS A 1 9  ? 212.263 231.427 141.143 1.00 30.00 ? 281 LYS C HB3  1 
ATOM 152  H HG2  . LYS A 1 9  ? 210.365 231.801 142.753 1.00 30.00 ? 281 LYS C HG2  1 
ATOM 153  H HG3  . LYS A 1 9  ? 209.390 232.358 141.375 1.00 30.00 ? 281 LYS C HG3  1 
ATOM 154  H HD2  . LYS A 1 9  ? 209.710 230.155 140.275 1.00 30.00 ? 281 LYS C HD2  1 
ATOM 155  H HD3  . LYS A 1 9  ? 210.729 229.640 141.614 1.00 30.00 ? 281 LYS C HD3  1 
ATOM 156  H HE2  . LYS A 1 9  ? 208.608 228.655 141.957 1.00 30.00 ? 281 LYS C HE2  1 
ATOM 157  H HE3  . LYS A 1 9  ? 208.809 229.903 143.170 1.00 30.00 ? 281 LYS C HE3  1 
ATOM 158  H HZ1  . LYS A 1 9  ? 207.208 230.184 140.698 1.00 30.00 ? 281 LYS C HZ1  1 
ATOM 159  H HZ2  . LYS A 1 9  ? 207.343 231.330 141.846 1.00 30.00 ? 281 LYS C HZ2  1 
ATOM 160  H HZ3  . LYS A 1 9  ? 206.596 229.931 142.171 1.00 30.00 ? 281 LYS C HZ3  1 
ATOM 161  N N    . LEU A 1 10 ? 214.427 233.201 141.325 1.00 30.00 ? 282 LEU C N    1 
ATOM 162  C CA   . LEU A 1 10 ? 215.754 233.033 140.746 1.00 30.00 ? 282 LEU C CA   1 
ATOM 163  C C    . LEU A 1 10 ? 216.285 231.668 141.181 1.00 30.00 ? 282 LEU C C    1 
ATOM 164  O O    . LEU A 1 10 ? 216.035 231.239 142.308 1.00 30.00 ? 282 LEU C O    1 
ATOM 165  C CB   . LEU A 1 10 ? 216.675 234.193 141.190 1.00 30.00 ? 282 LEU C CB   1 
ATOM 166  C CG   . LEU A 1 10 ? 218.134 234.116 140.689 1.00 30.00 ? 282 LEU C CG   1 
ATOM 167  C CD1  . LEU A 1 10 ? 218.704 235.516 140.490 1.00 30.00 ? 282 LEU C CD1  1 
ATOM 168  C CD2  . LEU A 1 10 ? 219.102 233.439 141.657 1.00 30.00 ? 282 LEU C CD2  1 
ATOM 169  H H    . LEU A 1 10 ? 214.235 232.649 142.146 1.00 30.00 ? 282 LEU C H    1 
ATOM 170  H HA   . LEU A 1 10 ? 215.677 233.045 139.659 1.00 30.00 ? 282 LEU C HA   1 
ATOM 171  H HB2  . LEU A 1 10 ? 216.233 235.114 140.819 1.00 30.00 ? 282 LEU C HB2  1 
ATOM 172  H HB3  . LEU A 1 10 ? 216.674 234.258 142.276 1.00 30.00 ? 282 LEU C HB3  1 
ATOM 173  H HG   . LEU A 1 10 ? 218.159 233.605 139.729 1.00 30.00 ? 282 LEU C HG   1 
ATOM 174  H HD11 . LEU A 1 10 ? 219.730 235.458 140.136 1.00 30.00 ? 282 LEU C HD11 1 
ATOM 175  H HD12 . LEU A 1 10 ? 218.684 236.072 141.424 1.00 30.00 ? 282 LEU C HD12 1 
ATOM 176  H HD13 . LEU A 1 10 ? 218.113 236.045 139.747 1.00 30.00 ? 282 LEU C HD13 1 
ATOM 177  H HD21 . LEU A 1 10 ? 220.081 233.343 141.196 1.00 30.00 ? 282 LEU C HD21 1 
ATOM 178  H HD22 . LEU A 1 10 ? 218.752 232.445 141.929 1.00 30.00 ? 282 LEU C HD22 1 
ATOM 179  H HD23 . LEU A 1 10 ? 219.189 234.026 142.566 1.00 30.00 ? 282 LEU C HD23 1 
ATOM 180  N N    . ASP A 1 11 ? 217.086 231.040 140.329 1.00 30.00 ? 283 ASP C N    1 
ATOM 181  C CA   . ASP A 1 11 ? 217.919 229.887 140.687 1.00 30.00 ? 283 ASP C CA   1 
ATOM 182  C C    . ASP A 1 11 ? 219.353 230.119 140.232 1.00 30.00 ? 283 ASP C C    1 
ATOM 183  O O    . ASP A 1 11 ? 219.575 230.505 139.092 1.00 30.00 ? 283 ASP C O    1 
ATOM 184  C CB   . ASP A 1 11 ? 217.453 228.575 140.036 1.00 30.00 ? 283 ASP C CB   1 
ATOM 185  C CG   . ASP A 1 11 ? 216.042 228.079 140.347 1.00 30.00 ? 283 ASP C CG   1 
ATOM 186  O OD1  . ASP A 1 11 ? 215.103 228.862 140.585 1.00 30.00 ? 283 ASP C OD1  1 
ATOM 187  O OD2  . ASP A 1 11 ? 215.854 226.850 140.243 1.00 30.00 ? 283 ASP C OD2  1 
ATOM 188  H H    . ASP A 1 11 ? 217.243 231.459 139.425 1.00 30.00 ? 283 ASP C H    1 
ATOM 189  H HA   . ASP A 1 11 ? 217.927 229.749 141.766 1.00 30.00 ? 283 ASP C HA   1 
ATOM 190  H HB2  . ASP A 1 11 ? 217.532 228.687 138.956 1.00 30.00 ? 283 ASP C HB2  1 
ATOM 191  H HB3  . ASP A 1 11 ? 218.157 227.800 140.332 1.00 30.00 ? 283 ASP C HB3  1 
ATOM 192  N N    . LEU A 1 12 ? 220.330 229.780 141.060 1.00 30.00 ? 284 LEU C N    1 
ATOM 193  C CA   . LEU A 1 12 ? 221.708 229.541 140.621 1.00 30.00 ? 284 LEU C CA   1 
ATOM 194  C C    . LEU A 1 12 ? 222.218 228.186 141.141 1.00 30.00 ? 284 LEU C C    1 
ATOM 195  O O    . LEU A 1 12 ? 223.411 227.997 141.375 1.00 30.00 ? 284 LEU C O    1 
ATOM 196  C CB   . LEU A 1 12 ? 222.587 230.749 140.999 1.00 30.00 ? 284 LEU C CB   1 
ATOM 197  C CG   . LEU A 1 12 ? 223.829 230.908 140.102 1.00 30.00 ? 284 LEU C CG   1 
ATOM 198  C CD1  . LEU A 1 12 ? 223.466 231.544 138.762 1.00 30.00 ? 284 LEU C CD1  1 
ATOM 199  C CD2  . LEU A 1 12 ? 224.872 231.805 140.760 1.00 30.00 ? 284 LEU C CD2  1 
ATOM 200  H H    . LEU A 1 12 ? 220.092 229.548 142.008 1.00 30.00 ? 284 LEU C H    1 
ATOM 201  H HA   . LEU A 1 12 ? 221.707 229.451 139.536 1.00 30.00 ? 284 LEU C HA   1 
ATOM 202  H HB2  . LEU A 1 12 ? 222.000 231.664 140.929 1.00 30.00 ? 284 LEU C HB2  1 
ATOM 203  H HB3  . LEU A 1 12 ? 222.901 230.643 142.035 1.00 30.00 ? 284 LEU C HB3  1 
ATOM 204  H HG   . LEU A 1 12 ? 224.285 229.938 139.915 1.00 30.00 ? 284 LEU C HG   1 
ATOM 205  H HD11 . LEU A 1 12 ? 223.058 232.538 138.924 1.00 30.00 ? 284 LEU C HD11 1 
ATOM 206  H HD12 . LEU A 1 12 ? 222.728 230.940 138.241 1.00 30.00 ? 284 LEU C HD12 1 
ATOM 207  H HD13 . LEU A 1 12 ? 224.354 231.618 138.138 1.00 30.00 ? 284 LEU C HD13 1 
ATOM 208  H HD21 . LEU A 1 12 ? 224.446 232.784 140.946 1.00 30.00 ? 284 LEU C HD21 1 
ATOM 209  H HD22 . LEU A 1 12 ? 225.741 231.905 140.116 1.00 30.00 ? 284 LEU C HD22 1 
ATOM 210  H HD23 . LEU A 1 12 ? 225.188 231.363 141.699 1.00 30.00 ? 284 LEU C HD23 1 
ATOM 211  N N    . SER A 1 13 ? 221.297 227.255 141.400 1.00 30.00 ? 285 SER C N    1 
ATOM 212  C CA   . SER A 1 13 ? 221.591 225.981 142.044 1.00 30.00 ? 285 SER C CA   1 
ATOM 213  C C    . SER A 1 13 ? 222.492 225.088 141.199 1.00 30.00 ? 285 SER C C    1 
ATOM 214  O O    . SER A 1 13 ? 222.361 225.001 139.984 1.00 30.00 ? 285 SER C O    1 
ATOM 215  C CB   . SER A 1 13 ? 220.290 225.274 142.433 1.00 30.00 ? 285 SER C CB   1 
ATOM 216  O OG   . SER A 1 13 ? 219.441 225.048 141.328 1.00 30.00 ? 285 SER C OG   1 
ATOM 217  H H    . SER A 1 13 ? 220.343 227.435 141.135 1.00 30.00 ? 285 SER C H    1 
ATOM 218  H HA   . SER A 1 13 ? 222.129 226.188 142.968 1.00 30.00 ? 285 SER C HA   1 
ATOM 219  H HB2  . SER A 1 13 ? 220.532 224.324 142.902 1.00 30.00 ? 285 SER C HB2  1 
ATOM 220  H HB3  . SER A 1 13 ? 219.762 225.887 143.160 1.00 30.00 ? 285 SER C HB3  1 
ATOM 221  H HG   . SER A 1 13 ? 218.631 224.657 141.650 1.00 30.00 ? 285 SER C HG   1 
ATOM 222  N N    . ASN A 1 14 ? 223.425 224.402 141.853 1.00 30.00 ? 286 ASN C N    1 
ATOM 223  C CA   . ASN A 1 14 ? 224.380 223.454 141.276 1.00 30.00 ? 286 ASN C CA   1 
ATOM 224  C C    . ASN A 1 14 ? 223.991 222.030 141.707 1.00 30.00 ? 286 ASN C C    1 
ATOM 225  O O    . ASN A 1 14 ? 223.758 221.783 142.892 1.00 30.00 ? 286 ASN C O    1 
ATOM 226  C CB   . ASN A 1 14 ? 225.782 223.879 141.750 1.00 30.00 ? 286 ASN C CB   1 
ATOM 227  C CG   . ASN A 1 14 ? 226.903 222.968 141.298 1.00 30.00 ? 286 ASN C CG   1 
ATOM 228  O OD1  . ASN A 1 14 ? 226.988 221.813 141.665 1.00 30.00 ? 286 ASN C OD1  1 
ATOM 229  N ND2  . ASN A 1 14 ? 227.823 223.457 140.510 1.00 30.00 ? 286 ASN C ND2  1 
ATOM 230  H H    . ASN A 1 14 ? 223.455 224.507 142.855 1.00 30.00 ? 286 ASN C H    1 
ATOM 231  H HA   . ASN A 1 14 ? 224.347 223.501 140.189 1.00 30.00 ? 286 ASN C HA   1 
ATOM 232  H HB2  . ASN A 1 14 ? 225.976 224.887 141.394 1.00 30.00 ? 286 ASN C HB2  1 
ATOM 233  H HB3  . ASN A 1 14 ? 225.804 223.903 142.837 1.00 30.00 ? 286 ASN C HB3  1 
ATOM 234  H HD21 . ASN A 1 14 ? 227.776 224.418 140.216 1.00 30.00 ? 286 ASN C HD21 1 
ATOM 235  H HD22 . ASN A 1 14 ? 228.593 222.865 140.245 1.00 30.00 ? 286 ASN C HD22 1 
ATOM 236  N N    . VAL A 1 15 ? 223.896 221.083 140.767 1.00 30.00 ? 287 VAL C N    1 
ATOM 237  C CA   . VAL A 1 15 ? 223.372 219.729 141.012 1.00 30.00 ? 287 VAL C CA   1 
ATOM 238  C C    . VAL A 1 15 ? 224.278 218.662 140.383 1.00 30.00 ? 287 VAL C C    1 
ATOM 239  O O    . VAL A 1 15 ? 223.831 217.806 139.628 1.00 30.00 ? 287 VAL C O    1 
ATOM 240  C CB   . VAL A 1 15 ? 221.888 219.616 140.590 1.00 30.00 ? 287 VAL C CB   1 
ATOM 241  C CG1  . VAL A 1 15 ? 221.198 218.388 141.198 1.00 30.00 ? 287 VAL C CG1  1 
ATOM 242  C CG2  . VAL A 1 15 ? 221.039 220.820 141.013 1.00 30.00 ? 287 VAL C CG2  1 
ATOM 243  H H    . VAL A 1 15 ? 224.112 221.328 139.814 1.00 30.00 ? 287 VAL C H    1 
ATOM 244  H HA   . VAL A 1 15 ? 223.401 219.538 142.084 1.00 30.00 ? 287 VAL C HA   1 
ATOM 245  H HB   . VAL A 1 15 ? 221.835 219.552 139.505 1.00 30.00 ? 287 VAL C HB   1 
ATOM 246  H HG11 . VAL A 1 15 ? 220.173 218.326 140.847 1.00 30.00 ? 287 VAL C HG11 1 
ATOM 247  H HG12 . VAL A 1 15 ? 221.199 218.455 142.280 1.00 30.00 ? 287 VAL C HG12 1 
ATOM 248  H HG13 . VAL A 1 15 ? 221.710 217.480 140.899 1.00 30.00 ? 287 VAL C HG13 1 
ATOM 249  H HG21 . VAL A 1 15 ? 221.376 221.719 140.503 1.00 30.00 ? 287 VAL C HG21 1 
ATOM 250  H HG22 . VAL A 1 15 ? 221.110 220.962 142.088 1.00 30.00 ? 287 VAL C HG22 1 
ATOM 251  H HG23 . VAL A 1 15 ? 219.996 220.660 140.748 1.00 30.00 ? 287 VAL C HG23 1 
ATOM 252  N N    . GLN A 1 16 ? 225.585 218.728 140.627 1.00 30.00 ? 288 GLN C N    1 
ATOM 253  C CA   . GLN A 1 16 ? 226.554 217.779 140.070 1.00 30.00 ? 288 GLN C CA   1 
ATOM 254  C C    . GLN A 1 16 ? 226.379 216.337 140.580 1.00 30.00 ? 288 GLN C C    1 
ATOM 255  O O    . GLN A 1 16 ? 225.823 216.094 141.647 1.00 30.00 ? 288 GLN C O    1 
ATOM 256  C CB   . GLN A 1 16 ? 227.977 218.265 140.367 1.00 30.00 ? 288 GLN C CB   1 
ATOM 257  C CG   . GLN A 1 16 ? 228.367 219.465 139.506 1.00 30.00 ? 288 GLN C CG   1 
ATOM 258  C CD   . GLN A 1 16 ? 229.670 220.090 139.984 1.00 30.00 ? 288 GLN C CD   1 
ATOM 259  O OE1  . GLN A 1 16 ? 230.726 219.927 139.392 1.00 30.00 ? 288 GLN C OE1  1 
ATOM 260  N NE2  . GLN A 1 16 ? 229.648 220.825 141.072 1.00 30.00 ? 288 GLN C NE2  1 
ATOM 261  H H    . GLN A 1 16 ? 225.919 219.461 141.236 1.00 30.00 ? 288 GLN C H    1 
ATOM 262  H HA   . GLN A 1 16 ? 226.429 217.751 138.989 1.00 30.00 ? 288 GLN C HA   1 
ATOM 263  H HB2  . GLN A 1 16 ? 228.056 218.519 141.422 1.00 30.00 ? 288 GLN C HB2  1 
ATOM 264  H HB3  . GLN A 1 16 ? 228.687 217.467 140.166 1.00 30.00 ? 288 GLN C HB3  1 
ATOM 265  H HG2  . GLN A 1 16 ? 228.482 219.152 138.471 1.00 30.00 ? 288 GLN C HG2  1 
ATOM 266  H HG3  . GLN A 1 16 ? 227.578 220.213 139.547 1.00 30.00 ? 288 GLN C HG3  1 
ATOM 267  H HE21 . GLN A 1 16 ? 228.772 220.992 141.544 1.00 30.00 ? 288 GLN C HE21 1 
ATOM 268  H HE22 . GLN A 1 16 ? 230.516 221.216 141.403 1.00 30.00 ? 288 GLN C HE22 1 
ATOM 269  N N    . SER A 1 17 ? 226.938 215.361 139.859 1.00 30.00 ? 289 SER C N    1 
ATOM 270  C CA   . SER A 1 17 ? 227.125 213.974 140.321 1.00 30.00 ? 289 SER C CA   1 
ATOM 271  C C    . SER A 1 17 ? 228.390 213.348 139.710 1.00 30.00 ? 289 SER C C    1 
ATOM 272  O O    . SER A 1 17 ? 228.611 213.478 138.511 1.00 30.00 ? 289 SER C O    1 
ATOM 273  C CB   . SER A 1 17 ? 225.879 213.149 139.979 1.00 30.00 ? 289 SER C CB   1 
ATOM 274  O OG   . SER A 1 17 ? 225.937 211.865 140.562 1.00 30.00 ? 289 SER C OG   1 
ATOM 275  H H    . SER A 1 17 ? 227.350 215.606 138.977 1.00 30.00 ? 289 SER C H    1 
ATOM 276  H HA   . SER A 1 17 ? 227.237 213.974 141.405 1.00 30.00 ? 289 SER C HA   1 
ATOM 277  H HB2  . SER A 1 17 ? 224.990 213.658 140.343 1.00 30.00 ? 289 SER C HB2  1 
ATOM 278  H HB3  . SER A 1 17 ? 225.800 213.050 138.898 1.00 30.00 ? 289 SER C HB3  1 
ATOM 279  H HG   . SER A 1 17 ? 225.540 211.907 141.422 1.00 30.00 ? 289 SER C HG   1 
ATOM 280  N N    . LYS A 1 18 ? 229.252 212.716 140.515 1.00 30.00 ? 290 LYS C N    1 
ATOM 281  C CA   . LYS A 1 18 ? 230.501 212.037 140.105 1.00 30.00 ? 290 LYS C CA   1 
ATOM 282  C C    . LYS A 1 18 ? 231.434 212.829 139.185 1.00 30.00 ? 290 LYS C C    1 
ATOM 283  O O    . LYS A 1 18 ? 232.136 212.261 138.353 1.00 30.00 ? 290 LYS C O    1 
ATOM 284  C CB   . LYS A 1 18 ? 230.218 210.625 139.566 1.00 30.00 ? 290 LYS C CB   1 
ATOM 285  C CG   . LYS A 1 18 ? 229.601 209.709 140.623 1.00 30.00 ? 290 LYS C CG   1 
ATOM 286  C CD   . LYS A 1 18 ? 229.927 208.242 140.337 1.00 30.00 ? 290 LYS C CD   1 
ATOM 287  C CE   . LYS A 1 18 ? 229.316 207.366 141.427 1.00 30.00 ? 290 LYS C CE   1 
ATOM 288  N NZ   . LYS A 1 18 ? 229.861 205.995 141.388 1.00 30.00 ? 290 LYS C NZ   1 
ATOM 289  H H    . LYS A 1 18 ? 229.017 212.689 141.494 1.00 30.00 ? 290 LYS C H    1 
ATOM 290  H HA   . LYS A 1 18 ? 231.093 211.909 141.010 1.00 30.00 ? 290 LYS C HA   1 
ATOM 291  H HB2  . LYS A 1 18 ? 229.568 210.676 138.696 1.00 30.00 ? 290 LYS C HB2  1 
ATOM 292  H HB3  . LYS A 1 18 ? 231.161 210.181 139.253 1.00 30.00 ? 290 LYS C HB3  1 
ATOM 293  H HG2  . LYS A 1 18 ? 230.014 209.963 141.596 1.00 30.00 ? 290 LYS C HG2  1 
ATOM 294  H HG3  . LYS A 1 18 ? 228.526 209.860 140.648 1.00 30.00 ? 290 LYS C HG3  1 
ATOM 295  H HD2  . LYS A 1 18 ? 229.535 207.959 139.362 1.00 30.00 ? 290 LYS C HD2  1 
ATOM 296  H HD3  . LYS A 1 18 ? 231.007 208.117 140.339 1.00 30.00 ? 290 LYS C HD3  1 
ATOM 297  H HE2  . LYS A 1 18 ? 229.519 207.814 142.396 1.00 30.00 ? 290 LYS C HE2  1 
ATOM 298  H HE3  . LYS A 1 18 ? 228.240 207.350 141.282 1.00 30.00 ? 290 LYS C HE3  1 
ATOM 299  H HZ1  . LYS A 1 18 ? 229.883 205.649 140.442 1.00 30.00 ? 290 LYS C HZ1  1 
ATOM 300  H HZ2  . LYS A 1 18 ? 229.317 205.369 141.960 1.00 30.00 ? 290 LYS C HZ2  1 
ATOM 301  H HZ3  . LYS A 1 18 ? 230.809 205.976 141.725 1.00 30.00 ? 290 LYS C HZ3  1 
ATOM 302  N N    . CYS A 1 19 ? 231.467 214.145 139.318 1.00 30.00 ? 291 CYS C N    1 
ATOM 303  C CA   . CYS A 1 19 ? 231.997 215.036 138.285 1.00 30.00 ? 291 CYS C CA   1 
ATOM 304  C C    . CYS A 1 19 ? 233.534 215.221 138.234 1.00 30.00 ? 291 CYS C C    1 
ATOM 305  O O    . CYS A 1 19 ? 234.000 216.019 137.420 1.00 30.00 ? 291 CYS C O    1 
ATOM 306  C CB   . CYS A 1 19 ? 231.273 216.371 138.426 1.00 30.00 ? 291 CYS C CB   1 
ATOM 307  S SG   . CYS A 1 19 ? 231.740 217.096 140.012 1.00 30.00 ? 291 CYS C SG   1 
ATOM 308  H H    . CYS A 1 19 ? 230.926 214.559 140.061 1.00 30.00 ? 291 CYS C H    1 
ATOM 309  H HA   . CYS A 1 19 ? 231.724 214.626 137.315 1.00 30.00 ? 291 CYS C HA   1 
ATOM 310  H HB2  . CYS A 1 19 ? 231.571 217.031 137.613 1.00 30.00 ? 291 CYS C HB2  1 
ATOM 311  H HB3  . CYS A 1 19 ? 230.195 216.227 138.377 1.00 30.00 ? 291 CYS C HB3  1 
ATOM 312  H HG   . CYS A 1 19 ? 231.491 218.357 139.684 1.00 30.00 ? 291 CYS C HG   1 
ATOM 313  N N    . GLY A 1 20 ? 234.347 214.547 139.062 1.00 30.00 ? 292 GLY C N    1 
ATOM 314  C CA   . GLY A 1 20 ? 235.773 214.879 139.178 1.00 30.00 ? 292 GLY C CA   1 
ATOM 315  C C    . GLY A 1 20 ? 236.716 213.801 139.699 1.00 30.00 ? 292 GLY C C    1 
ATOM 316  O O    . GLY A 1 20 ? 237.605 214.120 140.483 1.00 30.00 ? 292 GLY C O    1 
ATOM 317  H H    . GLY A 1 20 ? 233.937 213.906 139.722 1.00 30.00 ? 292 GLY C H    1 
ATOM 318  H HA2  . GLY A 1 20 ? 236.154 215.165 138.204 1.00 30.00 ? 292 GLY C HA2  1 
ATOM 319  H HA3  . GLY A 1 20 ? 235.865 215.744 139.828 1.00 30.00 ? 292 GLY C HA3  1 
ATOM 320  N N    . SER A 1 21 ? 236.547 212.533 139.322 1.00 30.00 ? 293 SER C N    1 
ATOM 321  C CA   . SER A 1 21 ? 237.474 211.467 139.750 1.00 30.00 ? 293 SER C CA   1 
ATOM 322  C C    . SER A 1 21 ? 238.862 211.546 139.083 1.00 30.00 ? 293 SER C C    1 
ATOM 323  O O    . SER A 1 21 ? 239.095 212.357 138.189 1.00 30.00 ? 293 SER C O    1 
ATOM 324  C CB   . SER A 1 21 ? 236.834 210.086 139.575 1.00 30.00 ? 293 SER C CB   1 
ATOM 325  O OG   . SER A 1 21 ? 236.952 209.605 138.255 1.00 30.00 ? 293 SER C OG   1 
ATOM 326  H H    . SER A 1 21 ? 235.820 212.312 138.659 1.00 30.00 ? 293 SER C H    1 
ATOM 327  H HA   . SER A 1 21 ? 237.634 211.590 140.820 1.00 30.00 ? 293 SER C HA   1 
ATOM 328  H HB2  . SER A 1 21 ? 237.333 209.384 140.240 1.00 30.00 ? 293 SER C HB2  1 
ATOM 329  H HB3  . SER A 1 21 ? 235.786 210.127 139.863 1.00 30.00 ? 293 SER C HB3  1 
ATOM 330  H HG   . SER A 1 21 ? 237.369 208.742 138.305 1.00 30.00 ? 293 SER C HG   1 
ATOM 331  N N    . LYS A 1 22 ? 239.804 210.699 139.502 1.00 30.00 ? 294 LYS C N    1 
ATOM 332  C CA   . LYS A 1 22 ? 241.185 210.669 138.996 1.00 30.00 ? 294 LYS C CA   1 
ATOM 333  C C    . LYS A 1 22 ? 241.775 209.251 139.000 1.00 30.00 ? 294 LYS C C    1 
ATOM 334  O O    . LYS A 1 22 ? 242.954 209.045 139.273 1.00 30.00 ? 294 LYS C O    1 
ATOM 335  C CB   . LYS A 1 22 ? 242.019 211.712 139.770 1.00 30.00 ? 294 LYS C CB   1 
ATOM 336  C CG   . LYS A 1 22 ? 242.813 212.664 138.867 1.00 30.00 ? 294 LYS C CG   1 
ATOM 337  C CD   . LYS A 1 22 ? 243.907 212.017 138.006 1.00 30.00 ? 294 LYS C CD   1 
ATOM 338  C CE   . LYS A 1 22 ? 245.057 211.470 138.854 1.00 30.00 ? 294 LYS C CE   1 
ATOM 339  N NZ   . LYS A 1 22 ? 246.211 211.089 138.008 1.00 30.00 ? 294 LYS C NZ   1 
ATOM 340  H H    . LYS A 1 22 ? 239.564 210.073 140.253 1.00 30.00 ? 294 LYS C H    1 
ATOM 341  H HA   . LYS A 1 22 ? 241.159 210.960 137.948 1.00 30.00 ? 294 LYS C HA   1 
ATOM 342  H HB2  . LYS A 1 22 ? 241.355 212.342 140.359 1.00 30.00 ? 294 LYS C HB2  1 
ATOM 343  H HB3  . LYS A 1 22 ? 242.686 211.227 140.482 1.00 30.00 ? 294 LYS C HB3  1 
ATOM 344  H HG2  . LYS A 1 22 ? 242.110 213.168 138.206 1.00 30.00 ? 294 LYS C HG2  1 
ATOM 345  H HG3  . LYS A 1 22 ? 243.272 213.427 139.493 1.00 30.00 ? 294 LYS C HG3  1 
ATOM 346  H HD2  . LYS A 1 22 ? 243.486 211.222 137.395 1.00 30.00 ? 294 LYS C HD2  1 
ATOM 347  H HD3  . LYS A 1 22 ? 244.290 212.790 137.342 1.00 30.00 ? 294 LYS C HD3  1 
ATOM 348  H HE2  . LYS A 1 22 ? 245.354 212.248 139.555 1.00 30.00 ? 294 LYS C HE2  1 
ATOM 349  H HE3  . LYS A 1 22 ? 244.706 210.614 139.427 1.00 30.00 ? 294 LYS C HE3  1 
ATOM 350  H HZ1  . LYS A 1 22 ? 246.549 211.884 137.495 1.00 30.00 ? 294 LYS C HZ1  1 
ATOM 351  H HZ2  . LYS A 1 22 ? 246.972 210.753 138.569 1.00 30.00 ? 294 LYS C HZ2  1 
ATOM 352  H HZ3  . LYS A 1 22 ? 245.960 210.381 137.341 1.00 30.00 ? 294 LYS C HZ3  1 
ATOM 353  N N    . ASP A 1 23 ? 240.946 208.255 138.707 1.00 30.00 ? 295 ASP C N    1 
ATOM 354  C CA   . ASP A 1 23 ? 241.299 206.824 138.649 1.00 30.00 ? 295 ASP C CA   1 
ATOM 355  C C    . ASP A 1 23 ? 242.558 206.535 137.812 1.00 30.00 ? 295 ASP C C    1 
ATOM 356  O O    . ASP A 1 23 ? 242.686 207.078 136.716 1.00 30.00 ? 295 ASP C O    1 
ATOM 357  C CB   . ASP A 1 23 ? 240.129 206.035 138.034 1.00 30.00 ? 295 ASP C CB   1 
ATOM 358  C CG   . ASP A 1 23 ? 238.808 206.241 138.765 1.00 30.00 ? 295 ASP C CG   1 
ATOM 359  O OD1  . ASP A 1 23 ? 238.159 207.289 138.565 1.00 30.00 ? 295 ASP C OD1  1 
ATOM 360  O OD2  . ASP A 1 23 ? 238.424 205.340 139.537 1.00 30.00 ? 295 ASP C OD2  1 
ATOM 361  H H    . ASP A 1 23 ? 239.997 208.500 138.469 1.00 30.00 ? 295 ASP C H    1 
ATOM 362  H HA   . ASP A 1 23 ? 241.468 206.460 139.662 1.00 30.00 ? 295 ASP C HA   1 
ATOM 363  H HB2  . ASP A 1 23 ? 239.999 206.350 137.001 1.00 30.00 ? 295 ASP C HB2  1 
ATOM 364  H HB3  . ASP A 1 23 ? 240.381 204.976 138.013 1.00 30.00 ? 295 ASP C HB3  1 
ATOM 365  N N    . ASN A 1 24 ? 243.482 205.689 138.290 1.00 30.00 ? 296 ASN C N    1 
ATOM 366  C CA   . ASN A 1 24 ? 244.653 205.237 137.525 1.00 30.00 ? 296 ASN C CA   1 
ATOM 367  C C    . ASN A 1 24 ? 245.336 203.986 138.126 1.00 30.00 ? 296 ASN C C    1 
ATOM 368  O O    . ASN A 1 24 ? 245.191 203.705 139.308 1.00 30.00 ? 296 ASN C O    1 
ATOM 369  C CB   . ASN A 1 24 ? 245.651 206.395 137.407 1.00 30.00 ? 296 ASN C CB   1 
ATOM 370  C CG   . ASN A 1 24 ? 246.216 206.824 138.739 1.00 30.00 ? 296 ASN C CG   1 
ATOM 371  O OD1  . ASN A 1 24 ? 247.295 206.413 139.121 1.00 30.00 ? 296 ASN C OD1  1 
ATOM 372  N ND2  . ASN A 1 24 ? 245.561 207.692 139.468 1.00 30.00 ? 296 ASN C ND2  1 
ATOM 373  H H    . ASN A 1 24 ? 243.328 205.256 139.188 1.00 30.00 ? 296 ASN C H    1 
ATOM 374  H HA   . ASN A 1 24 ? 244.325 204.968 136.522 1.00 30.00 ? 296 ASN C HA   1 
ATOM 375  H HB2  . ASN A 1 24 ? 246.472 206.081 136.766 1.00 30.00 ? 296 ASN C HB2  1 
ATOM 376  H HB3  . ASN A 1 24 ? 245.195 207.258 136.925 1.00 30.00 ? 296 ASN C HB3  1 
ATOM 377  H HD21 . ASN A 1 24 ? 244.643 208.015 139.199 1.00 30.00 ? 296 ASN C HD21 1 
ATOM 378  H HD22 . ASN A 1 24 ? 245.932 207.899 140.383 1.00 30.00 ? 296 ASN C HD22 1 
ATOM 379  N N    . ILE A 1 25 ? 246.107 203.248 137.320 1.00 30.00 ? 297 ILE C N    1 
ATOM 380  C CA   . ILE A 1 25 ? 246.895 202.044 137.672 1.00 30.00 ? 297 ILE C CA   1 
ATOM 381  C C    . ILE A 1 25 ? 248.302 202.207 137.083 1.00 30.00 ? 297 ILE C C    1 
ATOM 382  O O    . ILE A 1 25 ? 248.419 202.750 135.983 1.00 30.00 ? 297 ILE C O    1 
ATOM 383  C CB   . ILE A 1 25 ? 246.233 200.745 137.132 1.00 30.00 ? 297 ILE C CB   1 
ATOM 384  C CG1  . ILE A 1 25 ? 244.841 200.499 137.753 1.00 30.00 ? 297 ILE C CG1  1 
ATOM 385  C CG2  . ILE A 1 25 ? 247.133 199.519 137.360 1.00 30.00 ? 297 ILE C CG2  1 
ATOM 386  C CD1  . ILE A 1 25 ? 244.087 199.313 137.152 1.00 30.00 ? 297 ILE C CD1  1 
ATOM 387  H H    . ILE A 1 25 ? 246.183 203.552 136.365 1.00 30.00 ? 297 ILE C H    1 
ATOM 388  H HA   . ILE A 1 25 ? 246.985 201.963 138.755 1.00 30.00 ? 297 ILE C HA   1 
ATOM 389  H HB   . ILE A 1 25 ? 246.104 200.853 136.057 1.00 30.00 ? 297 ILE C HB   1 
ATOM 390  H HG12 . ILE A 1 25 ? 244.949 200.341 138.824 1.00 30.00 ? 297 ILE C HG12 1 
ATOM 391  H HG13 . ILE A 1 25 ? 244.221 201.378 137.599 1.00 30.00 ? 297 ILE C HG13 1 
ATOM 392  H HG21 . ILE A 1 25 ? 246.675 198.622 136.949 1.00 30.00 ? 297 ILE C HG21 1 
ATOM 393  H HG22 . ILE A 1 25 ? 248.087 199.626 136.846 1.00 30.00 ? 297 ILE C HG22 1 
ATOM 394  H HG23 . ILE A 1 25 ? 247.302 199.370 138.425 1.00 30.00 ? 297 ILE C HG23 1 
ATOM 395  H HD11 . ILE A 1 25 ? 243.079 199.291 137.558 1.00 30.00 ? 297 ILE C HD11 1 
ATOM 396  H HD12 . ILE A 1 25 ? 244.030 199.414 136.073 1.00 30.00 ? 297 ILE C HD12 1 
ATOM 397  H HD13 . ILE A 1 25 ? 244.577 198.377 137.400 1.00 30.00 ? 297 ILE C HD13 1 
ATOM 398  N N    . LYS A 1 26 ? 249.366 201.772 137.776 1.00 30.00 ? 298 LYS C N    1 
ATOM 399  C CA   . LYS A 1 26 ? 250.764 202.081 137.413 1.00 30.00 ? 298 LYS C CA   1 
ATOM 400  C C    . LYS A 1 26 ? 251.767 200.987 137.789 1.00 30.00 ? 298 LYS C C    1 
ATOM 401  O O    . LYS A 1 26 ? 251.448 200.084 138.551 1.00 30.00 ? 298 LYS C O    1 
ATOM 402  C CB   . LYS A 1 26 ? 251.182 203.420 138.059 1.00 30.00 ? 298 LYS C CB   1 
ATOM 403  C CG   . LYS A 1 26 ? 250.329 204.623 137.640 1.00 30.00 ? 298 LYS C CG   1 
ATOM 404  C CD   . LYS A 1 26 ? 250.913 205.936 138.158 1.00 30.00 ? 298 LYS C CD   1 
ATOM 405  C CE   . LYS A 1 26 ? 250.130 207.094 137.546 1.00 30.00 ? 298 LYS C CE   1 
ATOM 406  N NZ   . LYS A 1 26 ? 250.608 208.403 138.038 1.00 30.00 ? 298 LYS C NZ   1 
ATOM 407  H H    . LYS A 1 26 ? 249.206 201.281 138.642 1.00 30.00 ? 298 LYS C H    1 
ATOM 408  H HA   . LYS A 1 26 ? 250.830 202.197 136.332 1.00 30.00 ? 298 LYS C HA   1 
ATOM 409  H HB2  . LYS A 1 26 ? 251.162 203.332 139.144 1.00 30.00 ? 298 LYS C HB2  1 
ATOM 410  H HB3  . LYS A 1 26 ? 252.204 203.630 137.746 1.00 30.00 ? 298 LYS C HB3  1 
ATOM 411  H HG2  . LYS A 1 26 ? 250.292 204.663 136.553 1.00 30.00 ? 298 LYS C HG2  1 
ATOM 412  H HG3  . LYS A 1 26 ? 249.320 204.516 138.032 1.00 30.00 ? 298 LYS C HG3  1 
ATOM 413  H HD2  . LYS A 1 26 ? 250.847 205.966 139.243 1.00 30.00 ? 298 LYS C HD2  1 
ATOM 414  H HD3  . LYS A 1 26 ? 251.956 206.007 137.855 1.00 30.00 ? 298 LYS C HD3  1 
ATOM 415  H HE2  . LYS A 1 26 ? 250.227 207.055 136.464 1.00 30.00 ? 298 LYS C HE2  1 
ATOM 416  H HE3  . LYS A 1 26 ? 249.080 206.958 137.788 1.00 30.00 ? 298 LYS C HE3  1 
ATOM 417  H HZ1  . LYS A 1 26 ? 251.583 208.533 137.830 1.00 30.00 ? 298 LYS C HZ1  1 
ATOM 418  H HZ2  . LYS A 1 26 ? 250.106 209.158 137.607 1.00 30.00 ? 298 LYS C HZ2  1 
ATOM 419  H HZ3  . LYS A 1 26 ? 250.494 208.475 139.035 1.00 30.00 ? 298 LYS C HZ3  1 
ATOM 420  N N    . HIS A 1 27 ? 252.979 201.114 137.249 1.00 30.00 ? 299 HIS C N    1 
ATOM 421  C CA   . HIS A 1 27 ? 254.256 200.567 137.723 1.00 30.00 ? 299 HIS C CA   1 
ATOM 422  C C    . HIS A 1 27 ? 254.249 199.114 138.212 1.00 30.00 ? 299 HIS C C    1 
ATOM 423  O O    . HIS A 1 27 ? 254.156 198.854 139.411 1.00 30.00 ? 299 HIS C O    1 
ATOM 424  C CB   . HIS A 1 27 ? 254.839 201.508 138.787 1.00 30.00 ? 299 HIS C CB   1 
ATOM 425  C CG   . HIS A 1 27 ? 254.822 202.968 138.409 1.00 30.00 ? 299 HIS C CG   1 
ATOM 426  N ND1  . HIS A 1 27 ? 255.286 203.501 137.209 1.00 30.00 ? 299 HIS C ND1  1 
ATOM 427  C CD2  . HIS A 1 27 ? 254.398 203.990 139.199 1.00 30.00 ? 299 HIS C CD2  1 
ATOM 428  C CE1  . HIS A 1 27 ? 255.126 204.827 137.300 1.00 30.00 ? 299 HIS C CE1  1 
ATOM 429  N NE2  . HIS A 1 27 ? 254.591 205.148 138.484 1.00 30.00 ? 299 HIS C NE2  1 
ATOM 430  H H    . HIS A 1 27 ? 253.069 201.870 136.588 1.00 30.00 ? 299 HIS C H    1 
ATOM 431  H HA   . HIS A 1 27 ? 254.949 200.594 136.884 1.00 30.00 ? 299 HIS C HA   1 
ATOM 432  H HB2  . HIS A 1 27 ? 254.274 201.409 139.711 1.00 30.00 ? 299 HIS C HB2  1 
ATOM 433  H HB3  . HIS A 1 27 ? 255.866 201.209 138.986 1.00 30.00 ? 299 HIS C HB3  1 
ATOM 434  H HD2  . HIS A 1 27 ? 254.007 203.900 140.197 1.00 30.00 ? 299 HIS C HD2  1 
ATOM 435  H HE1  . HIS A 1 27 ? 255.401 205.537 136.539 1.00 30.00 ? 299 HIS C HE1  1 
ATOM 436  H HE2  . HIS A 1 27 ? 254.422 206.088 138.802 1.00 30.00 ? 299 HIS C HE2  1 
ATOM 437  N N    . VAL A 1 28 ? 254.424 198.150 137.303 1.00 30.00 ? 300 VAL C N    1 
ATOM 438  C CA   . VAL A 1 28 ? 254.520 196.706 137.633 1.00 30.00 ? 300 VAL C CA   1 
ATOM 439  C C    . VAL A 1 28 ? 255.853 196.094 137.158 1.00 30.00 ? 300 VAL C C    1 
ATOM 440  O O    . VAL A 1 28 ? 255.937 195.589 136.040 1.00 30.00 ? 300 VAL C O    1 
ATOM 441  C CB   . VAL A 1 28 ? 253.298 195.918 137.111 1.00 30.00 ? 300 VAL C CB   1 
ATOM 442  C CG1  . VAL A 1 28 ? 253.386 194.437 137.507 1.00 30.00 ? 300 VAL C CG1  1 
ATOM 443  C CG2  . VAL A 1 28 ? 251.987 196.468 137.684 1.00 30.00 ? 300 VAL C CG2  1 
ATOM 444  H H    . VAL A 1 28 ? 254.499 198.421 136.334 1.00 30.00 ? 300 VAL C H    1 
ATOM 445  H HA   . VAL A 1 28 ? 254.497 196.586 138.716 1.00 30.00 ? 300 VAL C HA   1 
ATOM 446  H HB   . VAL A 1 28 ? 253.254 195.988 136.025 1.00 30.00 ? 300 VAL C HB   1 
ATOM 447  H HG11 . VAL A 1 28 ? 254.220 193.947 137.012 1.00 30.00 ? 300 VAL C HG11 1 
ATOM 448  H HG12 . VAL A 1 28 ? 252.478 193.922 137.206 1.00 30.00 ? 300 VAL C HG12 1 
ATOM 449  H HG13 . VAL A 1 28 ? 253.501 194.350 138.584 1.00 30.00 ? 300 VAL C HG13 1 
ATOM 450  H HG21 . VAL A 1 28 ? 251.148 195.891 137.308 1.00 30.00 ? 300 VAL C HG21 1 
ATOM 451  H HG22 . VAL A 1 28 ? 251.844 197.499 137.377 1.00 30.00 ? 300 VAL C HG22 1 
ATOM 452  H HG23 . VAL A 1 28 ? 251.995 196.410 138.767 1.00 30.00 ? 300 VAL C HG23 1 
ATOM 453  N N    . PRO A 1 29 ? 256.923 196.145 137.972 1.00 30.00 ? 301 PRO C N    1 
ATOM 454  C CA   . PRO A 1 29 ? 258.218 195.522 137.682 1.00 30.00 ? 301 PRO C CA   1 
ATOM 455  C C    . PRO A 1 29 ? 258.203 194.005 137.430 1.00 30.00 ? 301 PRO C C    1 
ATOM 456  O O    . PRO A 1 29 ? 259.120 193.493 136.793 1.00 30.00 ? 301 PRO C O    1 
ATOM 457  C CB   . PRO A 1 29 ? 259.087 195.836 138.898 1.00 30.00 ? 301 PRO C CB   1 
ATOM 458  C CG   . PRO A 1 29 ? 258.520 197.157 139.399 1.00 30.00 ? 301 PRO C CG   1 
ATOM 459  C CD   . PRO A 1 29 ? 257.029 196.994 139.144 1.00 30.00 ? 301 PRO C CD   1 
ATOM 460  H HA   . PRO A 1 29 ? 258.650 196.016 136.813 1.00 30.00 ? 301 PRO C HA   1 
ATOM 461  H HB2  . PRO A 1 29 ? 258.955 195.078 139.667 1.00 30.00 ? 301 PRO C HB2  1 
ATOM 462  H HB3  . PRO A 1 29 ? 260.138 195.921 138.625 1.00 30.00 ? 301 PRO C HB3  1 
ATOM 463  H HG2  . PRO A 1 29 ? 258.735 197.318 140.454 1.00 30.00 ? 301 PRO C HG2  1 
ATOM 464  H HG3  . PRO A 1 29 ? 258.903 197.976 138.796 1.00 30.00 ? 301 PRO C HG3  1 
ATOM 465  H HD2  . PRO A 1 29 ? 256.555 196.502 139.989 1.00 30.00 ? 301 PRO C HD2  1 
ATOM 466  H HD3  . PRO A 1 29 ? 256.594 197.977 138.976 1.00 30.00 ? 301 PRO C HD3  1 
ATOM 467  N N    . GLY A 1 30 ? 257.186 193.275 137.879 1.00 30.00 ? 302 GLY C N    1 
ATOM 468  C CA   . GLY A 1 30 ? 256.939 191.893 137.459 1.00 30.00 ? 302 GLY C CA   1 
ATOM 469  C C    . GLY A 1 30 ? 257.906 190.837 138.010 1.00 30.00 ? 302 GLY C C    1 
ATOM 470  O O    . GLY A 1 30 ? 258.581 191.041 139.017 1.00 30.00 ? 302 GLY C O    1 
ATOM 471  H H    . GLY A 1 30 ? 256.488 193.731 138.443 1.00 30.00 ? 302 GLY C H    1 
ATOM 472  H HA2  . GLY A 1 30 ? 255.932 191.613 137.760 1.00 30.00 ? 302 GLY C HA2  1 
ATOM 473  H HA3  . GLY A 1 30 ? 256.974 191.847 136.373 1.00 30.00 ? 302 GLY C HA3  1 
ATOM 474  N N    . GLY A 1 31 ? 257.930 189.670 137.360 1.00 30.00 ? 303 GLY C N    1 
ATOM 475  C CA   . GLY A 1 31 ? 258.623 188.447 137.802 1.00 30.00 ? 303 GLY C CA   1 
ATOM 476  C C    . GLY A 1 31 ? 257.682 187.341 138.307 1.00 30.00 ? 303 GLY C C    1 
ATOM 477  O O    . GLY A 1 31 ? 258.088 186.191 138.464 1.00 30.00 ? 303 GLY C O    1 
ATOM 478  H H    . GLY A 1 31 ? 257.384 189.606 136.514 1.00 30.00 ? 303 GLY C H    1 
ATOM 479  H HA2  . GLY A 1 31 ? 259.196 188.054 136.965 1.00 30.00 ? 303 GLY C HA2  1 
ATOM 480  H HA3  . GLY A 1 31 ? 259.319 188.672 138.607 1.00 30.00 ? 303 GLY C HA3  1 
ATOM 481  N N    . GLY A 1 32 ? 256.409 187.667 138.521 1.00 30.00 ? 304 GLY C N    1 
ATOM 482  C CA   . GLY A 1 32 ? 255.340 186.773 138.966 1.00 30.00 ? 304 GLY C CA   1 
ATOM 483  C C    . GLY A 1 32 ? 253.970 187.283 138.519 1.00 30.00 ? 304 GLY C C    1 
ATOM 484  O O    . GLY A 1 32 ? 253.832 188.430 138.095 1.00 30.00 ? 304 GLY C O    1 
ATOM 485  H H    . GLY A 1 32 ? 256.147 188.624 138.344 1.00 30.00 ? 304 GLY C H    1 
ATOM 486  H HA2  . GLY A 1 32 ? 255.493 185.782 138.544 1.00 30.00 ? 304 GLY C HA2  1 
ATOM 487  H HA3  . GLY A 1 32 ? 255.347 186.691 140.050 1.00 30.00 ? 304 GLY C HA3  1 
ATOM 488  N N    . SER A 1 33 ? 252.966 186.420 138.534 1.00 30.00 ? 305 SER C N    1 
ATOM 489  C CA   . SER A 1 33 ? 251.761 186.590 137.723 1.00 30.00 ? 305 SER C CA   1 
ATOM 490  C C    . SER A 1 33 ? 250.714 187.555 138.311 1.00 30.00 ? 305 SER C C    1 
ATOM 491  O O    . SER A 1 33 ? 249.648 187.128 138.754 1.00 30.00 ? 305 SER C O    1 
ATOM 492  C CB   . SER A 1 33 ? 251.180 185.207 137.429 1.00 30.00 ? 305 SER C CB   1 
ATOM 493  O OG   . SER A 1 33 ? 250.093 185.309 136.538 1.00 30.00 ? 305 SER C OG   1 
ATOM 494  H H    . SER A 1 33 ? 253.140 185.511 138.936 1.00 30.00 ? 305 SER C H    1 
ATOM 495  H HA   . SER A 1 33 ? 252.066 187.000 136.762 1.00 30.00 ? 305 SER C HA   1 
ATOM 496  H HB2  . SER A 1 33 ? 251.950 184.587 136.974 1.00 30.00 ? 305 SER C HB2  1 
ATOM 497  H HB3  . SER A 1 33 ? 250.859 184.741 138.359 1.00 30.00 ? 305 SER C HB3  1 
ATOM 498  H HG   . SER A 1 33 ? 249.402 185.779 137.006 1.00 30.00 ? 305 SER C HG   1 
ATOM 499  N N    . VAL A 1 34 ? 250.980 188.859 138.284 1.00 30.00 ? 306 VAL C N    1 
ATOM 500  C CA   . VAL A 1 34 ? 250.051 189.921 138.732 1.00 30.00 ? 306 VAL C CA   1 
ATOM 501  C C    . VAL A 1 34 ? 248.710 189.897 137.987 1.00 30.00 ? 306 VAL C C    1 
ATOM 502  O O    . VAL A 1 34 ? 248.680 189.638 136.787 1.00 30.00 ? 306 VAL C O    1 
ATOM 503  C CB   . VAL A 1 34 ? 250.720 191.304 138.615 1.00 30.00 ? 306 VAL C CB   1 
ATOM 504  C CG1  . VAL A 1 34 ? 249.806 192.468 139.006 1.00 30.00 ? 306 VAL C CG1  1 
ATOM 505  C CG2  . VAL A 1 34 ? 251.940 191.362 139.536 1.00 30.00 ? 306 VAL C CG2  1 
ATOM 506  H H    . VAL A 1 34 ? 251.888 189.131 137.942 1.00 30.00 ? 306 VAL C H    1 
ATOM 507  H HA   . VAL A 1 34 ? 249.828 189.757 139.785 1.00 30.00 ? 306 VAL C HA   1 
ATOM 508  H HB   . VAL A 1 34 ? 251.055 191.460 137.592 1.00 30.00 ? 306 VAL C HB   1 
ATOM 509  H HG11 . VAL A 1 34 ? 248.999 192.580 138.283 1.00 30.00 ? 306 VAL C HG11 1 
ATOM 510  H HG12 . VAL A 1 34 ? 250.374 193.395 139.010 1.00 30.00 ? 306 VAL C HG12 1 
ATOM 511  H HG13 . VAL A 1 34 ? 249.392 192.301 139.996 1.00 30.00 ? 306 VAL C HG13 1 
ATOM 512  H HG21 . VAL A 1 34 ? 252.691 190.654 139.219 1.00 30.00 ? 306 VAL C HG21 1 
ATOM 513  H HG22 . VAL A 1 34 ? 251.647 191.136 140.551 1.00 30.00 ? 306 VAL C HG22 1 
ATOM 514  H HG23 . VAL A 1 34 ? 252.385 192.347 139.510 1.00 30.00 ? 306 VAL C HG23 1 
ATOM 515  N N    . GLN A 1 35 ? 247.605 190.211 138.668 1.00 30.00 ? 307 GLN C N    1 
ATOM 516  C CA   . GLN A 1 35 ? 246.274 190.377 138.076 1.00 30.00 ? 307 GLN C CA   1 
ATOM 517  C C    . GLN A 1 35 ? 245.462 191.458 138.795 1.00 30.00 ? 307 GLN C C    1 
ATOM 518  O O    . GLN A 1 35 ? 245.574 191.607 140.008 1.00 30.00 ? 307 GLN C O    1 
ATOM 519  C CB   . GLN A 1 35 ? 245.559 189.030 138.114 1.00 30.00 ? 307 GLN C CB   1 
ATOM 520  C CG   . GLN A 1 35 ? 244.107 189.103 137.631 1.00 30.00 ? 307 GLN C CG   1 
ATOM 521  C CD   . GLN A 1 35 ? 243.478 187.730 137.468 1.00 30.00 ? 307 GLN C CD   1 
ATOM 522  O OE1  . GLN A 1 35 ? 244.016 186.694 137.832 1.00 30.00 ? 307 GLN C OE1  1 
ATOM 523  N NE2  . GLN A 1 35 ? 242.294 187.675 136.919 1.00 30.00 ? 307 GLN C NE2  1 
ATOM 524  H H    . GLN A 1 35 ? 247.694 190.428 139.649 1.00 30.00 ? 307 GLN C H    1 
ATOM 525  H HA   . GLN A 1 35 ? 246.375 190.685 137.036 1.00 30.00 ? 307 GLN C HA   1 
ATOM 526  H HB2  . GLN A 1 35 ? 246.114 188.339 137.481 1.00 30.00 ? 307 GLN C HB2  1 
ATOM 527  H HB3  . GLN A 1 35 ? 245.566 188.646 139.131 1.00 30.00 ? 307 GLN C HB3  1 
ATOM 528  H HG2  . GLN A 1 35 ? 243.509 189.661 138.347 1.00 30.00 ? 307 GLN C HG2  1 
ATOM 529  H HG3  . GLN A 1 35 ? 244.077 189.614 136.670 1.00 30.00 ? 307 GLN C HG3  1 
ATOM 530  H HE21 . GLN A 1 35 ? 241.851 188.510 136.578 1.00 30.00 ? 307 GLN C HE21 1 
ATOM 531  H HE22 . GLN A 1 35 ? 241.895 186.765 136.765 1.00 30.00 ? 307 GLN C HE22 1 
ATOM 532  N N    . ILE A 1 36 ? 244.614 192.202 138.081 1.00 30.00 ? 308 ILE C N    1 
ATOM 533  C CA   . ILE A 1 36 ? 243.767 193.268 138.640 1.00 30.00 ? 308 ILE C CA   1 
ATOM 534  C C    . ILE A 1 36 ? 242.377 193.218 138.002 1.00 30.00 ? 308 ILE C C    1 
ATOM 535  O O    . ILE A 1 36 ? 242.266 192.972 136.807 1.00 30.00 ? 308 ILE C O    1 
ATOM 536  C CB   . ILE A 1 36 ? 244.411 194.663 138.434 1.00 30.00 ? 308 ILE C CB   1 
ATOM 537  C CG1  . ILE A 1 36 ? 245.816 194.740 139.060 1.00 30.00 ? 308 ILE C CG1  1 
ATOM 538  C CG2  . ILE A 1 36 ? 243.510 195.776 138.997 1.00 30.00 ? 308 ILE C CG2  1 
ATOM 539  C CD1  . ILE A 1 36 ? 246.566 196.045 138.792 1.00 30.00 ? 308 ILE C CD1  1 
ATOM 540  H H    . ILE A 1 36 ? 244.544 192.035 137.091 1.00 30.00 ? 308 ILE C H    1 
ATOM 541  H HA   . ILE A 1 36 ? 243.651 193.109 139.712 1.00 30.00 ? 308 ILE C HA   1 
ATOM 542  H HB   . ILE A 1 36 ? 244.520 194.830 137.363 1.00 30.00 ? 308 ILE C HB   1 
ATOM 543  H HG12 . ILE A 1 36 ? 245.745 194.590 140.135 1.00 30.00 ? 308 ILE C HG12 1 
ATOM 544  H HG13 . ILE A 1 36 ? 246.434 193.947 138.644 1.00 30.00 ? 308 ILE C HG13 1 
ATOM 545  H HG21 . ILE A 1 36 ? 242.569 195.824 138.458 1.00 30.00 ? 308 ILE C HG21 1 
ATOM 546  H HG22 . ILE A 1 36 ? 243.321 195.607 140.053 1.00 30.00 ? 308 ILE C HG22 1 
ATOM 547  H HG23 . ILE A 1 36 ? 243.977 196.750 138.877 1.00 30.00 ? 308 ILE C HG23 1 
ATOM 548  H HD11 . ILE A 1 36 ? 246.569 196.255 137.727 1.00 30.00 ? 308 ILE C HD11 1 
ATOM 549  H HD12 . ILE A 1 36 ? 247.593 195.942 139.134 1.00 30.00 ? 308 ILE C HD12 1 
ATOM 550  H HD13 . ILE A 1 36 ? 246.112 196.872 139.327 1.00 30.00 ? 308 ILE C HD13 1 
ATOM 551  N N    . VAL A 1 37 ? 241.320 193.495 138.759 1.00 30.00 ? 309 VAL C N    1 
ATOM 552  C CA   . VAL A 1 37 ? 239.987 193.837 138.240 1.00 30.00 ? 309 VAL C CA   1 
ATOM 553  C C    . VAL A 1 37 ? 239.556 195.167 138.855 1.00 30.00 ? 309 VAL C C    1 
ATOM 554  O O    . VAL A 1 37 ? 239.521 195.270 140.076 1.00 30.00 ? 309 VAL C O    1 
ATOM 555  C CB   . VAL A 1 37 ? 238.989 192.710 138.533 1.00 30.00 ? 309 VAL C CB   1 
ATOM 556  C CG1  . VAL A 1 37 ? 237.556 193.114 138.219 1.00 30.00 ? 309 VAL C CG1  1 
ATOM 557  C CG2  . VAL A 1 37 ? 239.296 191.467 137.713 1.00 30.00 ? 309 VAL C CG2  1 
ATOM 558  H H    . VAL A 1 37 ? 241.479 193.664 139.740 1.00 30.00 ? 309 VAL C H    1 
ATOM 559  H HA   . VAL A 1 37 ? 240.034 193.971 137.160 1.00 30.00 ? 309 VAL C HA   1 
ATOM 560  H HB   . VAL A 1 37 ? 239.042 192.449 139.586 1.00 30.00 ? 309 VAL C HB   1 
ATOM 561  H HG11 . VAL A 1 37 ? 236.889 192.268 138.364 1.00 30.00 ? 309 VAL C HG11 1 
ATOM 562  H HG12 . VAL A 1 37 ? 237.245 193.899 138.900 1.00 30.00 ? 309 VAL C HG12 1 
ATOM 563  H HG13 . VAL A 1 37 ? 237.486 193.453 137.191 1.00 30.00 ? 309 VAL C HG13 1 
ATOM 564  H HG21 . VAL A 1 37 ? 238.558 190.697 137.915 1.00 30.00 ? 309 VAL C HG21 1 
ATOM 565  H HG22 . VAL A 1 37 ? 239.270 191.704 136.658 1.00 30.00 ? 309 VAL C HG22 1 
ATOM 566  H HG23 . VAL A 1 37 ? 240.274 191.083 137.973 1.00 30.00 ? 309 VAL C HG23 1 
ATOM 567  N N    . TYR A 1 38 ? 239.262 196.189 138.053 1.00 30.00 ? 310 TYR C N    1 
ATOM 568  C CA   . TYR A 1 38 ? 239.074 197.562 138.521 1.00 30.00 ? 310 TYR C CA   1 
ATOM 569  C C    . TYR A 1 38 ? 237.640 198.074 138.345 1.00 30.00 ? 310 TYR C C    1 
ATOM 570  O O    . TYR A 1 38 ? 237.094 198.031 137.248 1.00 30.00 ? 310 TYR C O    1 
ATOM 571  C CB   . TYR A 1 38 ? 240.087 198.462 137.820 1.00 30.00 ? 310 TYR C CB   1 
ATOM 572  C CG   . TYR A 1 38 ? 240.181 199.844 138.424 1.00 30.00 ? 310 TYR C CG   1 
ATOM 573  C CD1  . TYR A 1 38 ? 239.325 200.865 137.985 1.00 30.00 ? 310 TYR C CD1  1 
ATOM 574  C CD2  . TYR A 1 38 ? 241.128 200.106 139.428 1.00 30.00 ? 310 TYR C CD2  1 
ATOM 575  C CE1  . TYR A 1 38 ? 239.383 202.142 138.566 1.00 30.00 ? 310 TYR C CE1  1 
ATOM 576  C CE2  . TYR A 1 38 ? 241.206 201.387 139.995 1.00 30.00 ? 310 TYR C CE2  1 
ATOM 577  C CZ   . TYR A 1 38 ? 240.320 202.398 139.584 1.00 30.00 ? 310 TYR C CZ   1 
ATOM 578  O OH   . TYR A 1 38 ? 240.360 203.606 140.193 1.00 30.00 ? 310 TYR C OH   1 
ATOM 579  H H    . TYR A 1 38 ? 239.272 196.036 137.058 1.00 30.00 ? 310 TYR C H    1 
ATOM 580  H HA   . TYR A 1 38 ? 239.311 197.607 139.583 1.00 30.00 ? 310 TYR C HA   1 
ATOM 581  H HB2  . TYR A 1 38 ? 241.067 197.993 137.872 1.00 30.00 ? 310 TYR C HB2  1 
ATOM 582  H HB3  . TYR A 1 38 ? 239.829 198.548 136.766 1.00 30.00 ? 310 TYR C HB3  1 
ATOM 583  H HD1  . TYR A 1 38 ? 238.610 200.665 137.201 1.00 30.00 ? 310 TYR C HD1  1 
ATOM 584  H HD2  . TYR A 1 38 ? 241.796 199.326 139.759 1.00 30.00 ? 310 TYR C HD2  1 
ATOM 585  H HE1  . TYR A 1 38 ? 238.711 202.919 138.236 1.00 30.00 ? 310 TYR C HE1  1 
ATOM 586  H HE2  . TYR A 1 38 ? 241.925 201.602 140.770 1.00 30.00 ? 310 TYR C HE2  1 
ATOM 587  H HH   . TYR A 1 38 ? 239.608 204.149 139.947 1.00 30.00 ? 310 TYR C HH   1 
ATOM 588  N N    . LYS A 1 39 ? 237.040 198.585 139.424 1.00 30.00 ? 311 LYS C N    1 
ATOM 589  C CA   . LYS A 1 39 ? 235.773 199.341 139.470 1.00 30.00 ? 311 LYS C CA   1 
ATOM 590  C C    . LYS A 1 39 ? 234.634 198.840 138.543 1.00 30.00 ? 311 LYS C C    1 
ATOM 591  O O    . LYS A 1 39 ? 234.057 199.657 137.826 1.00 30.00 ? 311 LYS C O    1 
ATOM 592  C CB   . LYS A 1 39 ? 236.154 200.816 139.255 1.00 30.00 ? 311 LYS C CB   1 
ATOM 593  C CG   . LYS A 1 39 ? 235.161 201.861 139.769 1.00 30.00 ? 311 LYS C CG   1 
ATOM 594  C CD   . LYS A 1 39 ? 235.822 203.235 139.625 1.00 30.00 ? 311 LYS C CD   1 
ATOM 595  C CE   . LYS A 1 39 ? 235.037 204.348 140.300 1.00 30.00 ? 311 LYS C CE   1 
ATOM 596  N NZ   . LYS A 1 39 ? 235.655 205.654 139.991 1.00 30.00 ? 311 LYS C NZ   1 
ATOM 597  H H    . LYS A 1 39 ? 237.576 198.553 140.277 1.00 30.00 ? 311 LYS C H    1 
ATOM 598  H HA   . LYS A 1 39 ? 235.379 199.252 140.481 1.00 30.00 ? 311 LYS C HA   1 
ATOM 599  H HB2  . LYS A 1 39 ? 237.089 200.982 139.788 1.00 30.00 ? 311 LYS C HB2  1 
ATOM 600  H HB3  . LYS A 1 39 ? 236.341 200.995 138.197 1.00 30.00 ? 311 LYS C HB3  1 
ATOM 601  H HG2  . LYS A 1 39 ? 234.239 201.833 139.196 1.00 30.00 ? 311 LYS C HG2  1 
ATOM 602  H HG3  . LYS A 1 39 ? 234.942 201.671 140.817 1.00 30.00 ? 311 LYS C HG3  1 
ATOM 603  H HD2  . LYS A 1 39 ? 236.803 203.199 140.080 1.00 30.00 ? 311 LYS C HD2  1 
ATOM 604  H HD3  . LYS A 1 39 ? 235.930 203.461 138.571 1.00 30.00 ? 311 LYS C HD3  1 
ATOM 605  H HE2  . LYS A 1 39 ? 234.009 204.319 139.953 1.00 30.00 ? 311 LYS C HE2  1 
ATOM 606  H HE3  . LYS A 1 39 ? 235.038 204.177 141.371 1.00 30.00 ? 311 LYS C HE3  1 
ATOM 607  H HZ1  . LYS A 1 39 ? 235.490 205.907 139.038 1.00 30.00 ? 311 LYS C HZ1  1 
ATOM 608  H HZ2  . LYS A 1 39 ? 236.652 205.615 140.103 1.00 30.00 ? 311 LYS C HZ2  1 
ATOM 609  H HZ3  . LYS A 1 39 ? 235.291 206.381 140.575 1.00 30.00 ? 311 LYS C HZ3  1 
ATOM 610  N N    . PRO A 1 40 ? 234.302 197.528 138.490 1.00 30.00 ? 312 PRO C N    1 
ATOM 611  C CA   . PRO A 1 40 ? 233.595 196.926 137.357 1.00 30.00 ? 312 PRO C CA   1 
ATOM 612  C C    . PRO A 1 40 ? 232.161 197.391 137.098 1.00 30.00 ? 312 PRO C C    1 
ATOM 613  O O    . PRO A 1 40 ? 231.635 197.102 136.030 1.00 30.00 ? 312 PRO C O    1 
ATOM 614  C CB   . PRO A 1 40 ? 233.620 195.415 137.584 1.00 30.00 ? 312 PRO C CB   1 
ATOM 615  C CG   . PRO A 1 40 ? 234.857 195.240 138.440 1.00 30.00 ? 312 PRO C CG   1 
ATOM 616  C CD   . PRO A 1 40 ? 234.764 196.450 139.351 1.00 30.00 ? 312 PRO C CD   1 
ATOM 617  H HA   . PRO A 1 40 ? 234.177 197.140 136.463 1.00 30.00 ? 312 PRO C HA   1 
ATOM 618  H HB2  . PRO A 1 40 ? 232.745 195.094 138.144 1.00 30.00 ? 312 PRO C HB2  1 
ATOM 619  H HB3  . PRO A 1 40 ? 233.710 194.867 136.650 1.00 30.00 ? 312 PRO C HB3  1 
ATOM 620  H HG2  . PRO A 1 40 ? 234.836 194.309 139.004 1.00 30.00 ? 312 PRO C HG2  1 
ATOM 621  H HG3  . PRO A 1 40 ? 235.744 195.314 137.815 1.00 30.00 ? 312 PRO C HG3  1 
ATOM 622  H HD2  . PRO A 1 40 ? 234.018 196.272 140.121 1.00 30.00 ? 312 PRO C HD2  1 
ATOM 623  H HD3  . PRO A 1 40 ? 235.725 196.625 139.825 1.00 30.00 ? 312 PRO C HD3  1 
ATOM 624  N N    . VAL A 1 41 ? 231.504 198.089 138.020 1.00 30.00 ? 313 VAL C N    1 
ATOM 625  C CA   . VAL A 1 41 ? 230.206 198.740 137.773 1.00 30.00 ? 313 VAL C CA   1 
ATOM 626  C C    . VAL A 1 41 ? 230.228 200.168 138.305 1.00 30.00 ? 313 VAL C C    1 
ATOM 627  O O    . VAL A 1 41 ? 230.664 200.403 139.430 1.00 30.00 ? 313 VAL C O    1 
ATOM 628  C CB   . VAL A 1 41 ? 229.041 197.928 138.371 1.00 30.00 ? 313 VAL C CB   1 
ATOM 629  C CG1  . VAL A 1 41 ? 227.689 198.633 138.260 1.00 30.00 ? 313 VAL C CG1  1 
ATOM 630  C CG2  . VAL A 1 41 ? 228.902 196.580 137.666 1.00 30.00 ? 313 VAL C CG2  1 
ATOM 631  H H    . VAL A 1 41 ? 231.976 198.295 138.884 1.00 30.00 ? 313 VAL C H    1 
ATOM 632  H HA   . VAL A 1 41 ? 230.034 198.802 136.699 1.00 30.00 ? 313 VAL C HA   1 
ATOM 633  H HB   . VAL A 1 41 ? 229.234 197.742 139.425 1.00 30.00 ? 313 VAL C HB   1 
ATOM 634  H HG11 . VAL A 1 41 ? 226.898 197.986 138.626 1.00 30.00 ? 313 VAL C HG11 1 
ATOM 635  H HG12 . VAL A 1 41 ? 227.488 198.898 137.227 1.00 30.00 ? 313 VAL C HG12 1 
ATOM 636  H HG13 . VAL A 1 41 ? 227.683 199.534 138.866 1.00 30.00 ? 313 VAL C HG13 1 
ATOM 637  H HG21 . VAL A 1 41 ? 228.049 196.037 138.064 1.00 30.00 ? 313 VAL C HG21 1 
ATOM 638  H HG22 . VAL A 1 41 ? 228.755 196.733 136.600 1.00 30.00 ? 313 VAL C HG22 1 
ATOM 639  H HG23 . VAL A 1 41 ? 229.795 195.981 137.818 1.00 30.00 ? 313 VAL C HG23 1 
ATOM 640  N N    . ASP A 1 42 ? 229.756 201.126 137.511 1.00 30.00 ? 314 ASP C N    1 
ATOM 641  C CA   . ASP A 1 42 ? 229.687 202.548 137.855 1.00 30.00 ? 314 ASP C CA   1 
ATOM 642  C C    . ASP A 1 42 ? 228.467 203.216 137.214 1.00 30.00 ? 314 ASP C C    1 
ATOM 643  O O    . ASP A 1 42 ? 228.148 202.927 136.063 1.00 30.00 ? 314 ASP C O    1 
ATOM 644  C CB   . ASP A 1 42 ? 230.979 203.233 137.405 1.00 30.00 ? 314 ASP C CB   1 
ATOM 645  C CG   . ASP A 1 42 ? 231.110 204.655 137.944 1.00 30.00 ? 314 ASP C CG   1 
ATOM 646  O OD1  . ASP A 1 42 ? 230.384 205.013 138.896 1.00 30.00 ? 314 ASP C OD1  1 
ATOM 647  O OD2  . ASP A 1 42 ? 231.984 205.394 137.449 1.00 30.00 ? 314 ASP C OD2  1 
ATOM 648  H H    . ASP A 1 42 ? 229.420 200.865 136.597 1.00 30.00 ? 314 ASP C H    1 
ATOM 649  H HA   . ASP A 1 42 ? 229.594 202.640 138.937 1.00 30.00 ? 314 ASP C HA   1 
ATOM 650  H HB2  . ASP A 1 42 ? 231.831 202.660 137.766 1.00 30.00 ? 314 ASP C HB2  1 
ATOM 651  H HB3  . ASP A 1 42 ? 231.011 203.234 136.319 1.00 30.00 ? 314 ASP C HB3  1 
ATOM 652  N N    . LEU A 1 43 ? 227.792 204.114 137.929 1.00 30.00 ? 315 LEU C N    1 
ATOM 653  C CA   . LEU A 1 43 ? 226.611 204.851 137.473 1.00 30.00 ? 315 LEU C CA   1 
ATOM 654  C C    . LEU A 1 43 ? 226.543 206.245 138.115 1.00 30.00 ? 315 LEU C C    1 
ATOM 655  O O    . LEU A 1 43 ? 227.020 206.461 139.225 1.00 30.00 ? 315 LEU C O    1 
ATOM 656  C CB   . LEU A 1 43 ? 225.310 204.084 137.791 1.00 30.00 ? 315 LEU C CB   1 
ATOM 657  C CG   . LEU A 1 43 ? 225.044 202.798 136.982 1.00 30.00 ? 315 LEU C CG   1 
ATOM 658  C CD1  . LEU A 1 43 ? 225.489 201.533 137.717 1.00 30.00 ? 315 LEU C CD1  1 
ATOM 659  C CD2  . LEU A 1 43 ? 223.541 202.644 136.745 1.00 30.00 ? 315 LEU C CD2  1 
ATOM 660  H H    . LEU A 1 43 ? 228.188 204.392 138.815 1.00 30.00 ? 315 LEU C H    1 
ATOM 661  H HA   . LEU A 1 43 ? 226.674 204.988 136.394 1.00 30.00 ? 315 LEU C HA   1 
ATOM 662  H HB2  . LEU A 1 43 ? 225.272 203.860 138.853 1.00 30.00 ? 315 LEU C HB2  1 
ATOM 663  H HB3  . LEU A 1 43 ? 224.489 204.769 137.591 1.00 30.00 ? 315 LEU C HB3  1 
ATOM 664  H HG   . LEU A 1 43 ? 225.530 202.858 136.010 1.00 30.00 ? 315 LEU C HG   1 
ATOM 665  H HD11 . LEU A 1 43 ? 225.288 200.657 137.107 1.00 30.00 ? 315 LEU C HD11 1 
ATOM 666  H HD12 . LEU A 1 43 ? 224.958 201.438 138.660 1.00 30.00 ? 315 LEU C HD12 1 
ATOM 667  H HD13 . LEU A 1 43 ? 226.557 201.570 137.917 1.00 30.00 ? 315 LEU C HD13 1 
ATOM 668  H HD21 . LEU A 1 43 ? 223.178 203.480 136.152 1.00 30.00 ? 315 LEU C HD21 1 
ATOM 669  H HD22 . LEU A 1 43 ? 223.010 202.613 137.693 1.00 30.00 ? 315 LEU C HD22 1 
ATOM 670  H HD23 . LEU A 1 43 ? 223.342 201.724 136.204 1.00 30.00 ? 315 LEU C HD23 1 
ATOM 671  N N    . SER A 1 44 ? 225.867 207.176 137.453 1.00 30.00 ? 316 SER C N    1 
ATOM 672  C CA   . SER A 1 44 ? 225.356 208.413 138.051 1.00 30.00 ? 316 SER C CA   1 
ATOM 673  C C    . SER A 1 44 ? 224.073 208.829 137.340 1.00 30.00 ? 316 SER C C    1 
ATOM 674  O O    . SER A 1 44 ? 223.865 208.469 136.184 1.00 30.00 ? 316 SER C O    1 
ATOM 675  C CB   . SER A 1 44 ? 226.399 209.528 138.013 1.00 30.00 ? 316 SER C CB   1 
ATOM 676  O OG   . SER A 1 44 ? 226.781 209.853 136.699 1.00 30.00 ? 316 SER C OG   1 
ATOM 677  H H    . SER A 1 44 ? 225.490 206.931 136.551 1.00 30.00 ? 316 SER C H    1 
ATOM 678  H HA   . SER A 1 44 ? 225.110 208.225 139.095 1.00 30.00 ? 316 SER C HA   1 
ATOM 679  H HB2  . SER A 1 44 ? 225.976 210.415 138.476 1.00 30.00 ? 316 SER C HB2  1 
ATOM 680  H HB3  . SER A 1 44 ? 227.275 209.227 138.581 1.00 30.00 ? 316 SER C HB3  1 
ATOM 681  H HG   . SER A 1 44 ? 227.277 209.137 136.355 1.00 30.00 ? 316 SER C HG   1 
ATOM 682  N N    . LYS A 1 45 ? 223.178 209.536 138.028 1.00 30.00 ? 317 LYS C N    1 
ATOM 683  C CA   . LYS A 1 45 ? 221.862 209.938 137.519 1.00 30.00 ? 317 LYS C CA   1 
ATOM 684  C C    . LYS A 1 45 ? 221.414 211.211 138.224 1.00 30.00 ? 317 LYS C C    1 
ATOM 685  O O    . LYS A 1 45 ? 221.574 211.321 139.436 1.00 30.00 ? 317 LYS C O    1 
ATOM 686  C CB   . LYS A 1 45 ? 220.873 208.776 137.729 1.00 30.00 ? 317 LYS C CB   1 
ATOM 687  C CG   . LYS A 1 45 ? 219.427 209.093 137.320 1.00 30.00 ? 317 LYS C CG   1 
ATOM 688  C CD   . LYS A 1 45 ? 218.522 207.896 137.626 1.00 30.00 ? 317 LYS C CD   1 
ATOM 689  C CE   . LYS A 1 45 ? 217.040 208.227 137.432 1.00 30.00 ? 317 LYS C CE   1 
ATOM 690  N NZ   . LYS A 1 45 ? 216.175 207.110 137.890 1.00 30.00 ? 317 LYS C NZ   1 
ATOM 691  H H    . LYS A 1 45 ? 223.400 209.782 138.980 1.00 30.00 ? 317 LYS C H    1 
ATOM 692  H HA   . LYS A 1 45 ? 221.927 210.148 136.452 1.00 30.00 ? 317 LYS C HA   1 
ATOM 693  H HB2  . LYS A 1 45 ? 221.214 207.915 137.158 1.00 30.00 ? 317 LYS C HB2  1 
ATOM 694  H HB3  . LYS A 1 45 ? 220.876 208.499 138.780 1.00 30.00 ? 317 LYS C HB3  1 
ATOM 695  H HG2  . LYS A 1 45 ? 219.068 209.948 137.888 1.00 30.00 ? 317 LYS C HG2  1 
ATOM 696  H HG3  . LYS A 1 45 ? 219.386 209.321 136.258 1.00 30.00 ? 317 LYS C HG3  1 
ATOM 697  H HD2  . LYS A 1 45 ? 218.800 207.066 136.984 1.00 30.00 ? 317 LYS C HD2  1 
ATOM 698  H HD3  . LYS A 1 45 ? 218.677 207.601 138.659 1.00 30.00 ? 317 LYS C HD3  1 
ATOM 699  H HE2  . LYS A 1 45 ? 216.800 209.129 137.990 1.00 30.00 ? 317 LYS C HE2  1 
ATOM 700  H HE3  . LYS A 1 45 ? 216.866 208.428 136.378 1.00 30.00 ? 317 LYS C HE3  1 
ATOM 701  H HZ1  . LYS A 1 45 ? 216.444 206.235 137.471 1.00 30.00 ? 317 LYS C HZ1  1 
ATOM 702  H HZ2  . LYS A 1 45 ? 216.264 206.944 138.879 1.00 30.00 ? 317 LYS C HZ2  1 
ATOM 703  H HZ3  . LYS A 1 45 ? 215.205 207.282 137.681 1.00 30.00 ? 317 LYS C HZ3  1 
ATOM 704  N N    . VAL A 1 46 ? 220.832 212.147 137.477 1.00 30.00 ? 318 VAL C N    1 
ATOM 705  C CA   . VAL A 1 46 ? 220.285 213.413 137.989 1.00 30.00 ? 318 VAL C CA   1 
ATOM 706  C C    . VAL A 1 46 ? 218.918 213.674 137.369 1.00 30.00 ? 318 VAL C C    1 
ATOM 707  O O    . VAL A 1 46 ? 218.763 213.540 136.160 1.00 30.00 ? 318 VAL C O    1 
ATOM 708  C CB   . VAL A 1 46 ? 221.239 214.591 137.705 1.00 30.00 ? 318 VAL C CB   1 
ATOM 709  C CG1  . VAL A 1 46 ? 220.699 215.889 138.300 1.00 30.00 ? 318 VAL C CG1  1 
ATOM 710  C CG2  . VAL A 1 46 ? 222.640 214.367 138.278 1.00 30.00 ? 318 VAL C CG2  1 
ATOM 711  H H    . VAL A 1 46 ? 220.724 211.960 136.491 1.00 30.00 ? 318 VAL C H    1 
ATOM 712  H HA   . VAL A 1 46 ? 220.155 213.341 139.068 1.00 30.00 ? 318 VAL C HA   1 
ATOM 713  H HB   . VAL A 1 46 ? 221.336 214.720 136.630 1.00 30.00 ? 318 VAL C HB   1 
ATOM 714  H HG11 . VAL A 1 46 ? 220.507 215.758 139.361 1.00 30.00 ? 318 VAL C HG11 1 
ATOM 715  H HG12 . VAL A 1 46 ? 219.786 216.185 137.795 1.00 30.00 ? 318 VAL C HG12 1 
ATOM 716  H HG13 . VAL A 1 46 ? 221.427 216.687 138.173 1.00 30.00 ? 318 VAL C HG13 1 
ATOM 717  H HG21 . VAL A 1 46 ? 223.255 215.244 138.115 1.00 30.00 ? 318 VAL C HG21 1 
ATOM 718  H HG22 . VAL A 1 46 ? 223.120 213.533 137.782 1.00 30.00 ? 318 VAL C HG22 1 
ATOM 719  H HG23 . VAL A 1 46 ? 222.576 214.167 139.339 1.00 30.00 ? 318 VAL C HG23 1 
ATOM 720  N N    . THR A 1 47 ? 217.932 214.087 138.162 1.00 30.00 ? 319 THR C N    1 
ATOM 721  C CA   . THR A 1 47 ? 216.599 214.508 137.689 1.00 30.00 ? 319 THR C CA   1 
ATOM 722  C C    . THR A 1 47 ? 216.155 215.775 138.408 1.00 30.00 ? 319 THR C C    1 
ATOM 723  O O    . THR A 1 47 ? 216.407 215.924 139.600 1.00 30.00 ? 319 THR C O    1 
ATOM 724  C CB   . THR A 1 47 ? 215.540 213.403 137.846 1.00 30.00 ? 319 THR C CB   1 
ATOM 725  O OG1  . THR A 1 47 ? 215.534 212.872 139.146 1.00 30.00 ? 319 THR C OG1  1 
ATOM 726  C CG2  . THR A 1 47 ? 215.765 212.215 136.918 1.00 30.00 ? 319 THR C CG2  1 
ATOM 727  H H    . THR A 1 47 ? 218.118 214.185 139.149 1.00 30.00 ? 319 THR C H    1 
ATOM 728  H HA   . THR A 1 47 ? 216.656 214.755 136.630 1.00 30.00 ? 319 THR C HA   1 
ATOM 729  H HB   . THR A 1 47 ? 214.560 213.824 137.627 1.00 30.00 ? 319 THR C HB   1 
ATOM 730  H HG1  . THR A 1 47 ? 215.331 213.585 139.738 1.00 30.00 ? 319 THR C HG1  1 
ATOM 731  H HG21 . THR A 1 47 ? 214.936 211.519 137.016 1.00 30.00 ? 319 THR C HG21 1 
ATOM 732  H HG22 . THR A 1 47 ? 215.806 212.560 135.888 1.00 30.00 ? 319 THR C HG22 1 
ATOM 733  H HG23 . THR A 1 47 ? 216.691 211.705 137.162 1.00 30.00 ? 319 THR C HG23 1 
ATOM 734  N N    . SER A 1 48 ? 215.505 216.704 137.705 1.00 30.00 ? 320 SER C N    1 
ATOM 735  C CA   . SER A 1 48 ? 215.175 218.027 138.234 1.00 30.00 ? 320 SER C CA   1 
ATOM 736  C C    . SER A 1 48 ? 213.906 218.622 137.619 1.00 30.00 ? 320 SER C C    1 
ATOM 737  O O    . SER A 1 48 ? 213.555 218.302 136.487 1.00 30.00 ? 320 SER C O    1 
ATOM 738  C CB   . SER A 1 48 ? 216.380 218.937 137.992 1.00 30.00 ? 320 SER C CB   1 
ATOM 739  O OG   . SER A 1 48 ? 216.211 220.160 138.670 1.00 30.00 ? 320 SER C OG   1 
ATOM 740  H H    . SER A 1 48 ? 215.296 216.527 136.733 1.00 30.00 ? 320 SER C H    1 
ATOM 741  H HA   . SER A 1 48 ? 215.022 217.959 139.309 1.00 30.00 ? 320 SER C HA   1 
ATOM 742  H HB2  . SER A 1 48 ? 217.280 218.451 138.361 1.00 30.00 ? 320 SER C HB2  1 
ATOM 743  H HB3  . SER A 1 48 ? 216.498 219.125 136.927 1.00 30.00 ? 320 SER C HB3  1 
ATOM 744  H HG   . SER A 1 48 ? 217.008 220.671 138.560 1.00 30.00 ? 320 SER C HG   1 
ATOM 745  N N    . LYS A 1 49 ? 213.210 219.482 138.369 1.00 30.00 ? 321 LYS C N    1 
ATOM 746  C CA   . LYS A 1 49 ? 212.036 220.282 137.957 1.00 30.00 ? 321 LYS C CA   1 
ATOM 747  C C    . LYS A 1 49 ? 210.957 219.517 137.189 1.00 30.00 ? 321 LYS C C    1 
ATOM 748  O O    . LYS A 1 49 ? 210.359 220.024 136.248 1.00 30.00 ? 321 LYS C O    1 
ATOM 749  C CB   . LYS A 1 49 ? 212.476 221.561 137.242 1.00 30.00 ? 321 LYS C CB   1 
ATOM 750  C CG   . LYS A 1 49 ? 213.249 222.463 138.196 1.00 30.00 ? 321 LYS C CG   1 
ATOM 751  C CD   . LYS A 1 49 ? 213.769 223.696 137.471 1.00 30.00 ? 321 LYS C CD   1 
ATOM 752  C CE   . LYS A 1 49 ? 214.554 224.532 138.472 1.00 30.00 ? 321 LYS C CE   1 
ATOM 753  N NZ   . LYS A 1 49 ? 215.172 225.712 137.841 1.00 30.00 ? 321 LYS C NZ   1 
ATOM 754  H H    . LYS A 1 49 ? 213.595 219.676 139.277 1.00 30.00 ? 321 LYS C H    1 
ATOM 755  H HA   . LYS A 1 49 ? 211.531 220.600 138.868 1.00 30.00 ? 321 LYS C HA   1 
ATOM 756  H HB2  . LYS A 1 49 ? 213.091 221.310 136.381 1.00 30.00 ? 321 LYS C HB2  1 
ATOM 757  H HB3  . LYS A 1 49 ? 211.603 222.114 136.900 1.00 30.00 ? 321 LYS C HB3  1 
ATOM 758  H HG2  . LYS A 1 49 ? 212.593 222.771 139.007 1.00 30.00 ? 321 LYS C HG2  1 
ATOM 759  H HG3  . LYS A 1 49 ? 214.099 221.926 138.612 1.00 30.00 ? 321 LYS C HG3  1 
ATOM 760  H HD2  . LYS A 1 49 ? 214.418 223.385 136.658 1.00 30.00 ? 321 LYS C HD2  1 
ATOM 761  H HD3  . LYS A 1 49 ? 212.936 224.272 137.077 1.00 30.00 ? 321 LYS C HD3  1 
ATOM 762  H HE2  . LYS A 1 49 ? 213.880 224.851 139.260 1.00 30.00 ? 321 LYS C HE2  1 
ATOM 763  H HE3  . LYS A 1 49 ? 215.317 223.908 138.921 1.00 30.00 ? 321 LYS C HE3  1 
ATOM 764  H HZ1  . LYS A 1 49 ? 214.493 226.263 137.357 1.00 30.00 ? 321 LYS C HZ1  1 
ATOM 765  H HZ2  . LYS A 1 49 ? 215.893 225.447 137.200 1.00 30.00 ? 321 LYS C HZ2  1 
ATOM 766  H HZ3  . LYS A 1 49 ? 215.579 226.280 138.561 1.00 30.00 ? 321 LYS C HZ3  1 
ATOM 767  N N    . CYS A 1 50 ? 210.698 218.284 137.589 1.00 30.00 ? 322 CYS C N    1 
ATOM 768  C CA   . CYS A 1 50 ? 209.599 217.469 137.075 1.00 30.00 ? 322 CYS C CA   1 
ATOM 769  C C    . CYS A 1 50 ? 208.260 217.810 137.745 1.00 30.00 ? 322 CYS C C    1 
ATOM 770  O O    . CYS A 1 50 ? 208.231 218.414 138.813 1.00 30.00 ? 322 CYS C O    1 
ATOM 771  C CB   . CYS A 1 50 ? 209.982 216.002 137.264 1.00 30.00 ? 322 CYS C CB   1 
ATOM 772  S SG   . CYS A 1 50 ? 211.433 215.677 136.236 1.00 30.00 ? 322 CYS C SG   1 
ATOM 773  H H    . CYS A 1 50 ? 211.215 217.939 138.381 1.00 30.00 ? 322 CYS C H    1 
ATOM 774  H HA   . CYS A 1 50 ? 209.480 217.647 136.007 1.00 30.00 ? 322 CYS C HA   1 
ATOM 775  H HB2  . CYS A 1 50 ? 210.209 215.799 138.306 1.00 30.00 ? 322 CYS C HB2  1 
ATOM 776  H HB3  . CYS A 1 50 ? 209.169 215.358 136.948 1.00 30.00 ? 322 CYS C HB3  1 
ATOM 777  H HG   . CYS A 1 50 ? 212.180 216.693 136.652 1.00 30.00 ? 322 CYS C HG   1 
ATOM 778  N N    . GLY A 1 51 ? 207.145 217.391 137.151 1.00 30.00 ? 323 GLY C N    1 
ATOM 779  C CA   . GLY A 1 51 ? 205.799 217.606 137.688 1.00 30.00 ? 323 GLY C CA   1 
ATOM 780  C C    . GLY A 1 51 ? 205.098 218.831 137.105 1.00 30.00 ? 323 GLY C C    1 
ATOM 781  O O    . GLY A 1 51 ? 205.259 219.145 135.935 1.00 30.00 ? 323 GLY C O    1 
ATOM 782  H H    . GLY A 1 51 ? 207.223 216.920 136.264 1.00 30.00 ? 323 GLY C H    1 
ATOM 783  H HA2  . GLY A 1 51 ? 205.177 216.739 137.475 1.00 30.00 ? 323 GLY C HA2  1 
ATOM 784  H HA3  . GLY A 1 51 ? 205.847 217.713 138.768 1.00 30.00 ? 323 GLY C HA3  1 
ATOM 785  N N    . SER A 1 52 ? 204.283 219.521 137.892 1.00 30.00 ? 324 SER C N    1 
ATOM 786  C CA   . SER A 1 52 ? 203.555 220.728 137.479 1.00 30.00 ? 324 SER C CA   1 
ATOM 787  C C    . SER A 1 52 ? 204.160 221.976 138.122 1.00 30.00 ? 324 SER C C    1 
ATOM 788  O O    . SER A 1 52 ? 204.280 222.047 139.342 1.00 30.00 ? 324 SER C O    1 
ATOM 789  C CB   . SER A 1 52 ? 202.084 220.585 137.869 1.00 30.00 ? 324 SER C CB   1 
ATOM 790  O OG   . SER A 1 52 ? 201.332 221.707 137.462 1.00 30.00 ? 324 SER C OG   1 
ATOM 791  H H    . SER A 1 52 ? 204.166 219.206 138.838 1.00 30.00 ? 324 SER C H    1 
ATOM 792  H HA   . SER A 1 52 ? 203.598 220.835 136.397 1.00 30.00 ? 324 SER C HA   1 
ATOM 793  H HB2  . SER A 1 52 ? 201.674 219.697 137.393 1.00 30.00 ? 324 SER C HB2  1 
ATOM 794  H HB3  . SER A 1 52 ? 202.009 220.465 138.947 1.00 30.00 ? 324 SER C HB3  1 
ATOM 795  H HG   . SER A 1 52 ? 200.424 221.505 137.654 1.00 30.00 ? 324 SER C HG   1 
ATOM 796  N N    . LEU A 1 53 ? 204.570 222.957 137.319 1.00 30.00 ? 325 LEU C N    1 
ATOM 797  C CA   . LEU A 1 53 ? 205.243 224.177 137.772 1.00 30.00 ? 325 LEU C CA   1 
ATOM 798  C C    . LEU A 1 53 ? 204.702 225.415 137.044 1.00 30.00 ? 325 LEU C C    1 
ATOM 799  O O    . LEU A 1 53 ? 204.422 225.365 135.851 1.00 30.00 ? 325 LEU C O    1 
ATOM 800  C CB   . LEU A 1 53 ? 206.765 224.070 137.557 1.00 30.00 ? 325 LEU C CB   1 
ATOM 801  C CG   . LEU A 1 53 ? 207.478 222.913 138.285 1.00 30.00 ? 325 LEU C CG   1 
ATOM 802  C CD1  . LEU A 1 53 ? 207.615 221.660 137.424 1.00 30.00 ? 325 LEU C CD1  1 
ATOM 803  C CD2  . LEU A 1 53 ? 208.906 223.309 138.655 1.00 30.00 ? 325 LEU C CD2  1 
ATOM 804  H H    . LEU A 1 53 ? 204.432 222.849 136.325 1.00 30.00 ? 325 LEU C H    1 
ATOM 805  H HA   . LEU A 1 53 ? 205.062 224.318 138.836 1.00 30.00 ? 325 LEU C HA   1 
ATOM 806  H HB2  . LEU A 1 53 ? 206.977 224.004 136.491 1.00 30.00 ? 325 LEU C HB2  1 
ATOM 807  H HB3  . LEU A 1 53 ? 207.198 225.006 137.904 1.00 30.00 ? 325 LEU C HB3  1 
ATOM 808  H HG   . LEU A 1 53 ? 206.947 222.669 139.205 1.00 30.00 ? 325 LEU C HG   1 
ATOM 809  H HD11 . LEU A 1 53 ? 208.219 221.872 136.545 1.00 30.00 ? 325 LEU C HD11 1 
ATOM 810  H HD12 . LEU A 1 53 ? 208.100 220.876 138.003 1.00 30.00 ? 325 LEU C HD12 1 
ATOM 811  H HD13 . LEU A 1 53 ? 206.638 221.304 137.104 1.00 30.00 ? 325 LEU C HD13 1 
ATOM 812  H HD21 . LEU A 1 53 ? 209.400 222.484 139.165 1.00 30.00 ? 325 LEU C HD21 1 
ATOM 813  H HD22 . LEU A 1 53 ? 209.468 223.566 137.759 1.00 30.00 ? 325 LEU C HD22 1 
ATOM 814  H HD23 . LEU A 1 53 ? 208.888 224.167 139.322 1.00 30.00 ? 325 LEU C HD23 1 
ATOM 815  N N    . GLY A 1 54 ? 204.612 226.551 137.734 1.00 30.00 ? 326 GLY C N    1 
ATOM 816  C CA   . GLY A 1 54 ? 204.457 227.876 137.119 1.00 30.00 ? 326 GLY C CA   1 
ATOM 817  C C    . GLY A 1 54 ? 203.102 228.222 136.506 1.00 30.00 ? 326 GLY C C    1 
ATOM 818  O O    . GLY A 1 54 ? 202.943 229.332 136.010 1.00 30.00 ? 326 GLY C O    1 
ATOM 819  H H    . GLY A 1 54 ? 204.838 226.519 138.717 1.00 30.00 ? 326 GLY C H    1 
ATOM 820  H HA2  . GLY A 1 54 ? 204.665 228.629 137.877 1.00 30.00 ? 326 GLY C HA2  1 
ATOM 821  H HA3  . GLY A 1 54 ? 205.201 227.985 136.333 1.00 30.00 ? 326 GLY C HA3  1 
ATOM 822  N N    . ASN A 1 55 ? 202.114 227.332 136.531 1.00 30.00 ? 327 ASN C N    1 
ATOM 823  C CA   . ASN A 1 55 ? 200.770 227.562 135.987 1.00 30.00 ? 327 ASN C CA   1 
ATOM 824  C C    . ASN A 1 55 ? 200.018 228.712 136.670 1.00 30.00 ? 327 ASN C C    1 
ATOM 825  O O    . ASN A 1 55 ? 200.226 228.989 137.847 1.00 30.00 ? 327 ASN C O    1 
ATOM 826  C CB   . ASN A 1 55 ? 199.986 226.249 136.068 1.00 30.00 ? 327 ASN C CB   1 
ATOM 827  C CG   . ASN A 1 55 ? 200.549 225.227 135.108 1.00 30.00 ? 327 ASN C CG   1 
ATOM 828  O OD1  . ASN A 1 55 ? 200.557 225.425 133.906 1.00 30.00 ? 327 ASN C OD1  1 
ATOM 829  N ND2  . ASN A 1 55 ? 201.027 224.103 135.572 1.00 30.00 ? 327 ASN C ND2  1 
ATOM 830  H H    . ASN A 1 55 ? 202.305 226.440 136.959 1.00 30.00 ? 327 ASN C H    1 
ATOM 831  H HA   . ASN A 1 55 ? 200.872 227.836 134.938 1.00 30.00 ? 327 ASN C HA   1 
ATOM 832  H HB2  . ASN A 1 55 ? 200.000 225.873 137.088 1.00 30.00 ? 327 ASN C HB2  1 
ATOM 833  H HB3  . ASN A 1 55 ? 198.949 226.422 135.787 1.00 30.00 ? 327 ASN C HB3  1 
ATOM 834  H HD21 . ASN A 1 55 ? 201.028 223.892 136.556 1.00 30.00 ? 327 ASN C HD21 1 
ATOM 835  H HD22 . ASN A 1 55 ? 201.369 223.433 134.905 1.00 30.00 ? 327 ASN C HD22 1 
ATOM 836  N N    . ILE A 1 56 ? 199.108 229.365 135.947 1.00 30.00 ? 328 ILE C N    1 
ATOM 837  C CA   . ILE A 1 56 ? 198.295 230.492 136.422 1.00 30.00 ? 328 ILE C CA   1 
ATOM 838  C C    . ILE A 1 56 ? 196.849 230.268 135.985 1.00 30.00 ? 328 ILE C C    1 
ATOM 839  O O    . ILE A 1 56 ? 196.617 229.865 134.850 1.00 30.00 ? 328 ILE C O    1 
ATOM 840  C CB   . ILE A 1 56 ? 198.863 231.828 135.894 1.00 30.00 ? 328 ILE C CB   1 
ATOM 841  C CG1  . ILE A 1 56 ? 200.317 232.046 136.373 1.00 30.00 ? 328 ILE C CG1  1 
ATOM 842  C CG2  . ILE A 1 56 ? 197.978 233.013 136.318 1.00 30.00 ? 328 ILE C CG2  1 
ATOM 843  C CD1  . ILE A 1 56 ? 201.009 233.238 135.728 1.00 30.00 ? 328 ILE C CD1  1 
ATOM 844  H H    . ILE A 1 56 ? 198.945 229.056 135.001 1.00 30.00 ? 328 ILE C H    1 
ATOM 845  H HA   . ILE A 1 56 ? 198.311 230.525 137.511 1.00 30.00 ? 328 ILE C HA   1 
ATOM 846  H HB   . ILE A 1 56 ? 198.866 231.784 134.806 1.00 30.00 ? 328 ILE C HB   1 
ATOM 847  H HG12 . ILE A 1 56 ? 200.334 232.171 137.449 1.00 30.00 ? 328 ILE C HG12 1 
ATOM 848  H HG13 . ILE A 1 56 ? 200.922 231.180 136.121 1.00 30.00 ? 328 ILE C HG13 1 
ATOM 849  H HG21 . ILE A 1 56 ? 198.350 233.939 135.886 1.00 30.00 ? 328 ILE C HG21 1 
ATOM 850  H HG22 . ILE A 1 56 ? 196.961 232.886 135.952 1.00 30.00 ? 328 ILE C HG22 1 
ATOM 851  H HG23 . ILE A 1 56 ? 197.964 233.106 137.401 1.00 30.00 ? 328 ILE C HG23 1 
ATOM 852  H HD11 . ILE A 1 56 ? 200.962 233.152 134.652 1.00 30.00 ? 328 ILE C HD11 1 
ATOM 853  H HD12 . ILE A 1 56 ? 202.053 233.257 136.035 1.00 30.00 ? 328 ILE C HD12 1 
ATOM 854  H HD13 . ILE A 1 56 ? 200.548 234.166 136.046 1.00 30.00 ? 328 ILE C HD13 1 
ATOM 855  N N    . HIS A 1 57 ? 195.872 230.533 136.852 1.00 30.00 ? 329 HIS C N    1 
ATOM 856  C CA   . HIS A 1 57 ? 194.437 230.287 136.609 1.00 30.00 ? 329 HIS C CA   1 
ATOM 857  C C    . HIS A 1 57 ? 193.578 231.493 137.003 1.00 30.00 ? 329 HIS C C    1 
ATOM 858  O O    . HIS A 1 57 ? 193.962 232.254 137.890 1.00 30.00 ? 329 HIS C O    1 
ATOM 859  C CB   . HIS A 1 57 ? 193.995 229.017 137.358 1.00 30.00 ? 329 HIS C CB   1 
ATOM 860  C CG   . HIS A 1 57 ? 194.665 227.750 136.897 1.00 30.00 ? 329 HIS C CG   1 
ATOM 861  N ND1  . HIS A 1 57 ? 194.169 226.886 135.922 1.00 30.00 ? 329 HIS C ND1  1 
ATOM 862  C CD2  . HIS A 1 57 ? 195.846 227.250 137.359 1.00 30.00 ? 329 HIS C CD2  1 
ATOM 863  C CE1  . HIS A 1 57 ? 195.066 225.892 135.818 1.00 30.00 ? 329 HIS C CE1  1 
ATOM 864  N NE2  . HIS A 1 57 ? 196.083 226.090 136.661 1.00 30.00 ? 329 HIS C NE2  1 
ATOM 865  H H    . HIS A 1 57 ? 196.127 230.918 137.749 1.00 30.00 ? 329 HIS C H    1 
ATOM 866  H HA   . HIS A 1 57 ? 194.267 230.119 135.546 1.00 30.00 ? 329 HIS C HA   1 
ATOM 867  H HB2  . HIS A 1 57 ? 194.186 229.152 138.421 1.00 30.00 ? 329 HIS C HB2  1 
ATOM 868  H HB3  . HIS A 1 57 ? 192.922 228.882 137.230 1.00 30.00 ? 329 HIS C HB3  1 
ATOM 869  H HD2  . HIS A 1 57 ? 196.470 227.688 138.120 1.00 30.00 ? 329 HIS C HD2  1 
ATOM 870  H HE1  . HIS A 1 57 ? 194.992 225.056 135.143 1.00 30.00 ? 329 HIS C HE1  1 
ATOM 871  H HE2  . HIS A 1 57 ? 196.878 225.477 136.757 1.00 30.00 ? 329 HIS C HE2  1 
ATOM 872  N N    . HIS A 1 58 ? 192.413 231.673 136.376 1.00 30.00 ? 330 HIS C N    1 
ATOM 873  C CA   . HIS A 1 58 ? 191.441 232.718 136.713 1.00 30.00 ? 330 HIS C CA   1 
ATOM 874  C C    . HIS A 1 58 ? 190.035 232.316 136.285 1.00 30.00 ? 330 HIS C C    1 
ATOM 875  O O    . HIS A 1 58 ? 189.775 232.177 135.089 1.00 30.00 ? 330 HIS C O    1 
ATOM 876  C CB   . HIS A 1 58 ? 191.843 234.027 136.036 1.00 30.00 ? 330 HIS C CB   1 
ATOM 877  C CG   . HIS A 1 58 ? 190.796 235.103 136.162 1.00 30.00 ? 330 HIS C CG   1 
ATOM 878  N ND1  . HIS A 1 58 ? 190.331 235.639 137.363 1.00 30.00 ? 330 HIS C ND1  1 
ATOM 879  C CD2  . HIS A 1 58 ? 190.151 235.720 135.133 1.00 30.00 ? 330 HIS C CD2  1 
ATOM 880  C CE1  . HIS A 1 58 ? 189.433 236.577 137.025 1.00 30.00 ? 330 HIS C CE1  1 
ATOM 881  N NE2  . HIS A 1 58 ? 189.295 236.637 135.696 1.00 30.00 ? 330 HIS C NE2  1 
ATOM 882  H H    . HIS A 1 58 ? 192.161 231.027 135.644 1.00 30.00 ? 330 HIS C H    1 
ATOM 883  H HA   . HIS A 1 58 ? 191.428 232.880 137.790 1.00 30.00 ? 330 HIS C HA   1 
ATOM 884  H HB2  . HIS A 1 58 ? 192.766 234.393 136.482 1.00 30.00 ? 330 HIS C HB2  1 
ATOM 885  H HB3  . HIS A 1 58 ? 192.029 233.845 134.979 1.00 30.00 ? 330 HIS C HB3  1 
ATOM 886  H HD2  . HIS A 1 58 ? 190.291 235.526 134.081 1.00 30.00 ? 330 HIS C HD2  1 
ATOM 887  H HE1  . HIS A 1 58 ? 188.904 237.203 137.726 1.00 30.00 ? 330 HIS C HE1  1 
ATOM 888  H HE2  . HIS A 1 58 ? 188.699 237.282 135.203 1.00 30.00 ? 330 HIS C HE2  1 
ATOM 889  N N    . LYS A 1 59 ? 189.138 232.088 137.251 1.00 30.00 ? 331 LYS C N    1 
ATOM 890  C CA   . LYS A 1 59 ? 187.866 231.371 137.036 1.00 30.00 ? 331 LYS C CA   1 
ATOM 891  C C    . LYS A 1 59 ? 186.698 231.925 137.882 1.00 30.00 ? 331 LYS C C    1 
ATOM 892  O O    . LYS A 1 59 ? 186.260 231.245 138.806 1.00 30.00 ? 331 LYS C O    1 
ATOM 893  C CB   . LYS A 1 59 ? 188.106 229.868 137.307 1.00 30.00 ? 331 LYS C CB   1 
ATOM 894  C CG   . LYS A 1 59 ? 189.097 229.176 136.354 1.00 30.00 ? 331 LYS C CG   1 
ATOM 895  C CD   . LYS A 1 59 ? 189.492 227.769 136.803 1.00 30.00 ? 331 LYS C CD   1 
ATOM 896  C CE   . LYS A 1 59 ? 188.302 226.811 136.872 1.00 30.00 ? 331 LYS C CE   1 
ATOM 897  N NZ   . LYS A 1 59 ? 188.757 225.408 137.025 1.00 30.00 ? 331 LYS C NZ   1 
ATOM 898  H H    . LYS A 1 59 ? 189.418 232.272 138.201 1.00 30.00 ? 331 LYS C H    1 
ATOM 899  H HA   . LYS A 1 59 ? 187.559 231.477 135.996 1.00 30.00 ? 331 LYS C HA   1 
ATOM 900  H HB2  . LYS A 1 59 ? 188.466 229.758 138.328 1.00 30.00 ? 331 LYS C HB2  1 
ATOM 901  H HB3  . LYS A 1 59 ? 187.154 229.347 137.223 1.00 30.00 ? 331 LYS C HB3  1 
ATOM 902  H HG2  . LYS A 1 59 ? 188.663 229.133 135.357 1.00 30.00 ? 331 LYS C HG2  1 
ATOM 903  H HG3  . LYS A 1 59 ? 190.023 229.743 136.299 1.00 30.00 ? 331 LYS C HG3  1 
ATOM 904  H HD2  . LYS A 1 59 ? 190.220 227.386 136.089 1.00 30.00 ? 331 LYS C HD2  1 
ATOM 905  H HD3  . LYS A 1 59 ? 189.969 227.825 137.780 1.00 30.00 ? 331 LYS C HD3  1 
ATOM 906  H HE2  . LYS A 1 59 ? 187.662 227.094 137.705 1.00 30.00 ? 331 LYS C HE2  1 
ATOM 907  H HE3  . LYS A 1 59 ? 187.720 226.909 135.958 1.00 30.00 ? 331 LYS C HE3  1 
ATOM 908  H HZ1  . LYS A 1 59 ? 187.978 224.770 137.034 1.00 30.00 ? 331 LYS C HZ1  1 
ATOM 909  H HZ2  . LYS A 1 59 ? 189.363 225.143 136.265 1.00 30.00 ? 331 LYS C HZ2  1 
ATOM 910  H HZ3  . LYS A 1 59 ? 189.277 225.273 137.877 1.00 30.00 ? 331 LYS C HZ3  1 
ATOM 911  N N    . PRO A 1 60 ? 186.197 233.149 137.644 1.00 30.00 ? 332 PRO C N    1 
ATOM 912  C CA   . PRO A 1 60 ? 185.111 233.737 138.439 1.00 30.00 ? 332 PRO C CA   1 
ATOM 913  C C    . PRO A 1 60 ? 183.721 233.121 138.180 1.00 30.00 ? 332 PRO C C    1 
ATOM 914  O O    . PRO A 1 60 ? 183.379 232.788 137.057 1.00 30.00 ? 332 PRO C O    1 
ATOM 915  C CB   . PRO A 1 60 ? 185.125 235.230 138.101 1.00 30.00 ? 332 PRO C CB   1 
ATOM 916  C CG   . PRO A 1 60 ? 185.742 235.285 136.710 1.00 30.00 ? 332 PRO C CG   1 
ATOM 917  C CD   . PRO A 1 60 ? 186.729 234.127 136.713 1.00 30.00 ? 332 PRO C CD   1 
ATOM 918  H HA   . PRO A 1 60 ? 185.341 233.628 139.498 1.00 30.00 ? 332 PRO C HA   1 
ATOM 919  H HB2  . PRO A 1 60 ? 184.131 235.669 138.117 1.00 30.00 ? 332 PRO C HB2  1 
ATOM 920  H HB3  . PRO A 1 60 ? 185.770 235.754 138.804 1.00 30.00 ? 332 PRO C HB3  1 
ATOM 921  H HG2  . PRO A 1 60 ? 184.974 235.096 135.963 1.00 30.00 ? 332 PRO C HG2  1 
ATOM 922  H HG3  . PRO A 1 60 ? 186.236 236.237 136.528 1.00 30.00 ? 332 PRO C HG3  1 
ATOM 923  H HD2  . PRO A 1 60 ? 186.830 233.714 135.712 1.00 30.00 ? 332 PRO C HD2  1 
ATOM 924  H HD3  . PRO A 1 60 ? 187.696 234.471 137.074 1.00 30.00 ? 332 PRO C HD3  1 
ATOM 925  N N    . GLY A 1 61 ? 182.889 233.027 139.214 1.00 30.00 ? 333 GLY C N    1 
ATOM 926  C CA   . GLY A 1 61 ? 181.508 232.515 139.179 1.00 30.00 ? 333 GLY C CA   1 
ATOM 927  C C    . GLY A 1 61 ? 181.204 231.545 140.324 1.00 30.00 ? 333 GLY C C    1 
ATOM 928  O O    . GLY A 1 61 ? 181.997 230.655 140.626 1.00 30.00 ? 333 GLY C O    1 
ATOM 929  H H    . GLY A 1 61 ? 183.240 233.326 140.102 1.00 30.00 ? 333 GLY C H    1 
ATOM 930  H HA2  . GLY A 1 61 ? 180.821 233.356 139.242 1.00 30.00 ? 333 GLY C HA2  1 
ATOM 931  H HA3  . GLY A 1 61 ? 181.314 232.000 138.239 1.00 30.00 ? 333 GLY C HA3  1 
ATOM 932  N N    . GLY A 1 62 ? 180.055 231.696 140.978 1.00 30.00 ? 334 GLY C N    1 
ATOM 933  C CA   . GLY A 1 62 ? 179.775 231.038 142.260 1.00 30.00 ? 334 GLY C CA   1 
ATOM 934  C C    . GLY A 1 62 ? 179.315 229.575 142.200 1.00 30.00 ? 334 GLY C C    1 
ATOM 935  O O    . GLY A 1 62 ? 179.429 228.861 143.192 1.00 30.00 ? 334 GLY C O    1 
ATOM 936  H H    . GLY A 1 62 ? 179.424 232.419 140.668 1.00 30.00 ? 334 GLY C H    1 
ATOM 937  H HA2  . GLY A 1 62 ? 180.660 231.091 142.890 1.00 30.00 ? 334 GLY C HA2  1 
ATOM 938  H HA3  . GLY A 1 62 ? 178.989 231.594 142.763 1.00 30.00 ? 334 GLY C HA3  1 
ATOM 939  N N    . GLY A 1 63 ? 178.789 229.115 141.064 1.00 30.00 ? 335 GLY C N    1 
ATOM 940  C CA   . GLY A 1 63 ? 178.166 227.793 140.924 1.00 30.00 ? 335 GLY C CA   1 
ATOM 941  C C    . GLY A 1 63 ? 179.100 226.635 140.553 1.00 30.00 ? 335 GLY C C    1 
ATOM 942  O O    . GLY A 1 63 ? 178.638 225.503 140.414 1.00 30.00 ? 335 GLY C O    1 
ATOM 943  H H    . GLY A 1 63 ? 178.725 229.755 140.288 1.00 30.00 ? 335 GLY C H    1 
ATOM 944  H HA2  . GLY A 1 63 ? 177.660 227.528 141.849 1.00 30.00 ? 335 GLY C HA2  1 
ATOM 945  H HA3  . GLY A 1 63 ? 177.414 227.851 140.142 1.00 30.00 ? 335 GLY C HA3  1 
ATOM 946  N N    . GLN A 1 64 ? 180.380 226.896 140.307 1.00 30.00 ? 336 GLN C N    1 
ATOM 947  C CA   . GLN A 1 64 ? 181.264 225.949 139.621 1.00 30.00 ? 336 GLN C CA   1 
ATOM 948  C C    . GLN A 1 64 ? 181.650 224.721 140.464 1.00 30.00 ? 336 GLN C C    1 
ATOM 949  O O    . GLN A 1 64 ? 181.321 224.617 141.644 1.00 30.00 ? 336 GLN C O    1 
ATOM 950  C CB   . GLN A 1 64 ? 182.475 226.718 139.068 1.00 30.00 ? 336 GLN C CB   1 
ATOM 951  C CG   . GLN A 1 64 ? 183.470 227.182 140.131 1.00 30.00 ? 336 GLN C CG   1 
ATOM 952  C CD   . GLN A 1 64 ? 184.516 228.103 139.529 1.00 30.00 ? 336 GLN C CD   1 
ATOM 953  O OE1  . GLN A 1 64 ? 185.489 227.680 138.930 1.00 30.00 ? 336 GLN C OE1  1 
ATOM 954  N NE2  . GLN A 1 64 ? 184.369 229.388 139.681 1.00 30.00 ? 336 GLN C NE2  1 
ATOM 955  H H    . GLN A 1 64 ? 180.709 227.836 140.464 1.00 30.00 ? 336 GLN C H    1 
ATOM 956  H HA   . GLN A 1 64 ? 180.722 225.564 138.759 1.00 30.00 ? 336 GLN C HA   1 
ATOM 957  H HB2  . GLN A 1 64 ? 182.997 226.079 138.358 1.00 30.00 ? 336 GLN C HB2  1 
ATOM 958  H HB3  . GLN A 1 64 ? 182.113 227.588 138.522 1.00 30.00 ? 336 GLN C HB3  1 
ATOM 959  H HG2  . GLN A 1 64 ? 182.934 227.705 140.919 1.00 30.00 ? 336 GLN C HG2  1 
ATOM 960  H HG3  . GLN A 1 64 ? 183.970 226.321 140.567 1.00 30.00 ? 336 GLN C HG3  1 
ATOM 961  H HE21 . GLN A 1 64 ? 183.558 229.761 140.142 1.00 30.00 ? 336 GLN C HE21 1 
ATOM 962  H HE22 . GLN A 1 64 ? 185.099 229.993 139.337 1.00 30.00 ? 336 GLN C HE22 1 
ATOM 963  N N    . VAL A 1 65 ? 182.391 223.800 139.850 1.00 30.00 ? 337 VAL C N    1 
ATOM 964  C CA   . VAL A 1 65 ? 182.988 222.596 140.447 1.00 30.00 ? 337 VAL C CA   1 
ATOM 965  C C    . VAL A 1 65 ? 184.397 222.439 139.882 1.00 30.00 ? 337 VAL C C    1 
ATOM 966  O O    . VAL A 1 65 ? 184.673 222.881 138.772 1.00 30.00 ? 337 VAL C O    1 
ATOM 967  C CB   . VAL A 1 65 ? 182.121 221.354 140.164 1.00 30.00 ? 337 VAL C CB   1 
ATOM 968  C CG1  . VAL A 1 65 ? 182.770 220.031 140.593 1.00 30.00 ? 337 VAL C CG1  1 
ATOM 969  C CG2  . VAL A 1 65 ? 180.760 221.458 140.864 1.00 30.00 ? 337 VAL C CG2  1 
ATOM 970  H H    . VAL A 1 65 ? 182.647 223.982 138.893 1.00 30.00 ? 337 VAL C H    1 
ATOM 971  H HA   . VAL A 1 65 ? 183.073 222.716 141.526 1.00 30.00 ? 337 VAL C HA   1 
ATOM 972  H HB   . VAL A 1 65 ? 181.937 221.294 139.093 1.00 30.00 ? 337 VAL C HB   1 
ATOM 973  H HG11 . VAL A 1 65 ? 182.072 219.213 140.440 1.00 30.00 ? 337 VAL C HG11 1 
ATOM 974  H HG12 . VAL A 1 65 ? 183.044 220.074 141.646 1.00 30.00 ? 337 VAL C HG12 1 
ATOM 975  H HG13 . VAL A 1 65 ? 183.653 219.820 139.993 1.00 30.00 ? 337 VAL C HG13 1 
ATOM 976  H HG21 . VAL A 1 65 ? 180.173 220.563 140.673 1.00 30.00 ? 337 VAL C HG21 1 
ATOM 977  H HG22 . VAL A 1 65 ? 180.204 222.308 140.476 1.00 30.00 ? 337 VAL C HG22 1 
ATOM 978  H HG23 . VAL A 1 65 ? 180.898 221.585 141.934 1.00 30.00 ? 337 VAL C HG23 1 
ATOM 979  N N    . GLU A 1 66 ? 185.310 221.817 140.619 1.00 30.00 ? 338 GLU C N    1 
ATOM 980  C CA   . GLU A 1 66 ? 186.688 221.568 140.188 1.00 30.00 ? 338 GLU C CA   1 
ATOM 981  C C    . GLU A 1 66 ? 187.238 220.270 140.797 1.00 30.00 ? 338 GLU C C    1 
ATOM 982  O O    . GLU A 1 66 ? 186.952 219.946 141.944 1.00 30.00 ? 338 GLU C O    1 
ATOM 983  C CB   . GLU A 1 66 ? 187.551 222.782 140.566 1.00 30.00 ? 338 GLU C CB   1 
ATOM 984  C CG   . GLU A 1 66 ? 189.047 222.628 140.263 1.00 30.00 ? 338 GLU C CG   1 
ATOM 985  C CD   . GLU A 1 66 ? 189.762 223.983 140.334 1.00 30.00 ? 338 GLU C CD   1 
ATOM 986  O OE1  . GLU A 1 66 ? 189.920 224.539 141.442 1.00 30.00 ? 338 GLU C OE1  1 
ATOM 987  O OE2  . GLU A 1 66 ? 190.139 224.510 139.265 1.00 30.00 ? 338 GLU C OE2  1 
ATOM 988  H H    . GLU A 1 66 ? 185.038 221.452 141.518 1.00 30.00 ? 338 GLU C H    1 
ATOM 989  H HA   . GLU A 1 66 ? 186.707 221.458 139.105 1.00 30.00 ? 338 GLU C HA   1 
ATOM 990  H HB2  . GLU A 1 66 ? 187.178 223.647 140.022 1.00 30.00 ? 338 GLU C HB2  1 
ATOM 991  H HB3  . GLU A 1 66 ? 187.428 222.982 141.629 1.00 30.00 ? 338 GLU C HB3  1 
ATOM 992  H HG2  . GLU A 1 66 ? 189.487 221.936 140.977 1.00 30.00 ? 338 GLU C HG2  1 
ATOM 993  H HG3  . GLU A 1 66 ? 189.168 222.208 139.268 1.00 30.00 ? 338 GLU C HG3  1 
ATOM 994  N N    . VAL A 1 67 ? 188.043 219.527 140.045 1.00 30.00 ? 339 VAL C N    1 
ATOM 995  C CA   . VAL A 1 67 ? 188.704 218.285 140.467 1.00 30.00 ? 339 VAL C CA   1 
ATOM 996  C C    . VAL A 1 67 ? 190.084 218.229 139.817 1.00 30.00 ? 339 VAL C C    1 
ATOM 997  O O    . VAL A 1 67 ? 190.213 218.593 138.652 1.00 30.00 ? 339 VAL C O    1 
ATOM 998  C CB   . VAL A 1 67 ? 187.885 217.048 140.050 1.00 30.00 ? 339 VAL C CB   1 
ATOM 999  C CG1  . VAL A 1 67 ? 188.461 215.763 140.652 1.00 30.00 ? 339 VAL C CG1  1 
ATOM 1000 C CG2  . VAL A 1 67 ? 186.408 217.123 140.450 1.00 30.00 ? 339 VAL C CG2  1 
ATOM 1001 H H    . VAL A 1 67 ? 188.234 219.846 139.111 1.00 30.00 ? 339 VAL C H    1 
ATOM 1002 H HA   . VAL A 1 67 ? 188.824 218.287 141.549 1.00 30.00 ? 339 VAL C HA   1 
ATOM 1003 H HB   . VAL A 1 67 ? 187.921 216.960 138.966 1.00 30.00 ? 339 VAL C HB   1 
ATOM 1004 H HG11 . VAL A 1 67 ? 187.859 214.912 140.354 1.00 30.00 ? 339 VAL C HG11 1 
ATOM 1005 H HG12 . VAL A 1 67 ? 189.471 215.593 140.292 1.00 30.00 ? 339 VAL C HG12 1 
ATOM 1006 H HG13 . VAL A 1 67 ? 188.470 215.824 141.734 1.00 30.00 ? 339 VAL C HG13 1 
ATOM 1007 H HG21 . VAL A 1 67 ? 185.902 216.197 140.189 1.00 30.00 ? 339 VAL C HG21 1 
ATOM 1008 H HG22 . VAL A 1 67 ? 185.915 217.933 139.918 1.00 30.00 ? 339 VAL C HG22 1 
ATOM 1009 H HG23 . VAL A 1 67 ? 186.325 217.281 141.522 1.00 30.00 ? 339 VAL C HG23 1 
ATOM 1010 N N    . LYS A 1 68 ? 191.115 217.751 140.513 1.00 30.00 ? 340 LYS C N    1 
ATOM 1011 C CA   . LYS A 1 68 ? 192.485 217.561 139.990 1.00 30.00 ? 340 LYS C CA   1 
ATOM 1012 C C    . LYS A 1 68 ? 193.118 216.288 140.546 1.00 30.00 ? 340 LYS C C    1 
ATOM 1013 O O    . LYS A 1 68 ? 192.689 215.789 141.581 1.00 30.00 ? 340 LYS C O    1 
ATOM 1014 C CB   . LYS A 1 68 ? 193.383 218.766 140.332 1.00 30.00 ? 340 LYS C CB   1 
ATOM 1015 C CG   . LYS A 1 68 ? 192.930 220.094 139.705 1.00 30.00 ? 340 LYS C CG   1 
ATOM 1016 C CD   . LYS A 1 68 ? 193.968 221.217 139.858 1.00 30.00 ? 340 LYS C CD   1 
ATOM 1017 C CE   . LYS A 1 68 ? 194.296 221.514 141.324 1.00 30.00 ? 340 LYS C CE   1 
ATOM 1018 N NZ   . LYS A 1 68 ? 195.263 222.628 141.465 1.00 30.00 ? 340 LYS C NZ   1 
ATOM 1019 H H    . LYS A 1 68 ? 190.940 217.450 141.455 1.00 30.00 ? 340 LYS C H    1 
ATOM 1020 H HA   . LYS A 1 68 ? 192.450 217.455 138.907 1.00 30.00 ? 340 LYS C HA   1 
ATOM 1021 H HB2  . LYS A 1 68 ? 193.429 218.873 141.415 1.00 30.00 ? 340 LYS C HB2  1 
ATOM 1022 H HB3  . LYS A 1 68 ? 194.392 218.560 139.980 1.00 30.00 ? 340 LYS C HB3  1 
ATOM 1023 H HG2  . LYS A 1 68 ? 192.755 219.943 138.642 1.00 30.00 ? 340 LYS C HG2  1 
ATOM 1024 H HG3  . LYS A 1 68 ? 191.997 220.409 140.166 1.00 30.00 ? 340 LYS C HG3  1 
ATOM 1025 H HD2  . LYS A 1 68 ? 194.875 220.930 139.336 1.00 30.00 ? 340 LYS C HD2  1 
ATOM 1026 H HD3  . LYS A 1 68 ? 193.573 222.115 139.388 1.00 30.00 ? 340 LYS C HD3  1 
ATOM 1027 H HE2  . LYS A 1 68 ? 193.370 221.758 141.837 1.00 30.00 ? 340 LYS C HE2  1 
ATOM 1028 H HE3  . LYS A 1 68 ? 194.707 220.616 141.779 1.00 30.00 ? 340 LYS C HE3  1 
ATOM 1029 H HZ1  . LYS A 1 68 ? 196.126 222.429 140.986 1.00 30.00 ? 340 LYS C HZ1  1 
ATOM 1030 H HZ2  . LYS A 1 68 ? 194.885 223.482 141.088 1.00 30.00 ? 340 LYS C HZ2  1 
ATOM 1031 H HZ3  . LYS A 1 68 ? 195.483 222.795 142.434 1.00 30.00 ? 340 LYS C HZ3  1 
ATOM 1032 N N    . SER A 1 69 ? 194.145 215.766 139.887 1.00 30.00 ? 341 SER C N    1 
ATOM 1033 C CA   . SER A 1 69 ? 195.005 214.701 140.424 1.00 30.00 ? 341 SER C CA   1 
ATOM 1034 C C    . SER A 1 69 ? 196.413 214.763 139.826 1.00 30.00 ? 341 SER C C    1 
ATOM 1035 O O    . SER A 1 69 ? 196.585 215.285 138.729 1.00 30.00 ? 341 SER C O    1 
ATOM 1036 C CB   . SER A 1 69 ? 194.350 213.341 140.191 1.00 30.00 ? 341 SER C CB   1 
ATOM 1037 O OG   . SER A 1 69 ? 195.108 212.306 140.781 1.00 30.00 ? 341 SER C OG   1 
ATOM 1038 H H    . SER A 1 69 ? 194.441 216.215 139.033 1.00 30.00 ? 341 SER C H    1 
ATOM 1039 H HA   . SER A 1 69 ? 195.108 214.837 141.500 1.00 30.00 ? 341 SER C HA   1 
ATOM 1040 H HB2  . SER A 1 69 ? 193.355 213.336 140.631 1.00 30.00 ? 341 SER C HB2  1 
ATOM 1041 H HB3  . SER A 1 69 ? 194.260 213.161 139.122 1.00 30.00 ? 341 SER C HB3  1 
ATOM 1042 H HG   . SER A 1 69 ? 194.637 211.487 140.666 1.00 30.00 ? 341 SER C HG   1 
ATOM 1043 N N    . GLU A 1 70 ? 197.431 214.246 140.517 1.00 30.00 ? 342 GLU C N    1 
ATOM 1044 C CA   . GLU A 1 70 ? 198.840 214.209 140.085 1.00 30.00 ? 342 GLU C CA   1 
ATOM 1045 C C    . GLU A 1 70 ? 199.566 212.971 140.620 1.00 30.00 ? 342 GLU C C    1 
ATOM 1046 O O    . GLU A 1 70 ? 199.191 212.420 141.655 1.00 30.00 ? 342 GLU C O    1 
ATOM 1047 C CB   . GLU A 1 70 ? 199.598 215.453 140.573 1.00 30.00 ? 342 GLU C CB   1 
ATOM 1048 C CG   . GLU A 1 70 ? 199.114 216.773 139.973 1.00 30.00 ? 342 GLU C CG   1 
ATOM 1049 C CD   . GLU A 1 70 ? 200.001 217.962 140.366 1.00 30.00 ? 342 GLU C CD   1 
ATOM 1050 O OE1  . GLU A 1 70 ? 201.217 217.778 140.594 1.00 30.00 ? 342 GLU C OE1  1 
ATOM 1051 O OE2  . GLU A 1 70 ? 199.486 219.101 140.426 1.00 30.00 ? 342 GLU C OE2  1 
ATOM 1052 H H    . GLU A 1 70 ? 197.215 213.781 141.386 1.00 30.00 ? 342 GLU C H    1 
ATOM 1053 H HA   . GLU A 1 70 ? 198.888 214.175 138.997 1.00 30.00 ? 342 GLU C HA   1 
ATOM 1054 H HB2  . GLU A 1 70 ? 199.527 215.504 141.656 1.00 30.00 ? 342 GLU C HB2  1 
ATOM 1055 H HB3  . GLU A 1 70 ? 200.643 215.323 140.304 1.00 30.00 ? 342 GLU C HB3  1 
ATOM 1056 H HG2  . GLU A 1 70 ? 199.109 216.682 138.889 1.00 30.00 ? 342 GLU C HG2  1 
ATOM 1057 H HG3  . GLU A 1 70 ? 198.098 216.958 140.313 1.00 30.00 ? 342 GLU C HG3  1 
ATOM 1058 N N    . LYS A 1 71 ? 200.648 212.548 139.961 1.00 30.00 ? 343 LYS C N    1 
ATOM 1059 C CA   . LYS A 1 71 ? 201.562 211.510 140.458 1.00 30.00 ? 343 LYS C CA   1 
ATOM 1060 C C    . LYS A 1 71 ? 202.972 211.702 139.898 1.00 30.00 ? 343 LYS C C    1 
ATOM 1061 O O    . LYS A 1 71 ? 203.119 212.174 138.777 1.00 30.00 ? 343 LYS C O    1 
ATOM 1062 C CB   . LYS A 1 71 ? 200.965 210.134 140.120 1.00 30.00 ? 343 LYS C CB   1 
ATOM 1063 C CG   . LYS A 1 71 ? 201.903 208.963 140.433 1.00 30.00 ? 343 LYS C CG   1 
ATOM 1064 C CD   . LYS A 1 71 ? 201.240 207.608 140.197 1.00 30.00 ? 343 LYS C CD   1 
ATOM 1065 C CE   . LYS A 1 71 ? 202.301 206.515 140.339 1.00 30.00 ? 343 LYS C CE   1 
ATOM 1066 N NZ   . LYS A 1 71 ? 201.736 205.157 140.205 1.00 30.00 ? 343 LYS C NZ   1 
ATOM 1067 H H    . LYS A 1 71 ? 200.923 213.044 139.127 1.00 30.00 ? 343 LYS C H    1 
ATOM 1068 H HA   . LYS A 1 71 ? 201.635 211.596 141.542 1.00 30.00 ? 343 LYS C HA   1 
ATOM 1069 H HB2  . LYS A 1 71 ? 200.045 209.999 140.682 1.00 30.00 ? 343 LYS C HB2  1 
ATOM 1070 H HB3  . LYS A 1 71 ? 200.715 210.109 139.064 1.00 30.00 ? 343 LYS C HB3  1 
ATOM 1071 H HG2  . LYS A 1 71 ? 202.771 209.024 139.783 1.00 30.00 ? 343 LYS C HG2  1 
ATOM 1072 H HG3  . LYS A 1 71 ? 202.220 209.022 141.469 1.00 30.00 ? 343 LYS C HG3  1 
ATOM 1073 H HD2  . LYS A 1 71 ? 200.448 207.467 140.929 1.00 30.00 ? 343 LYS C HD2  1 
ATOM 1074 H HD3  . LYS A 1 71 ? 200.817 207.572 139.195 1.00 30.00 ? 343 LYS C HD3  1 
ATOM 1075 H HE2  . LYS A 1 71 ? 203.064 206.666 139.582 1.00 30.00 ? 343 LYS C HE2  1 
ATOM 1076 H HE3  . LYS A 1 71 ? 202.773 206.621 141.312 1.00 30.00 ? 343 LYS C HE3  1 
ATOM 1077 H HZ1  . LYS A 1 71 ? 202.463 204.464 140.284 1.00 30.00 ? 343 LYS C HZ1  1 
ATOM 1078 H HZ2  . LYS A 1 71 ? 201.298 205.037 139.310 1.00 30.00 ? 343 LYS C HZ2  1 
ATOM 1079 H HZ3  . LYS A 1 71 ? 201.052 204.974 140.915 1.00 30.00 ? 343 LYS C HZ3  1 
ATOM 1080 N N    . LEU A 1 72 ? 203.991 211.279 140.640 1.00 30.00 ? 344 LEU C N    1 
ATOM 1081 C CA   . LEU A 1 72 ? 205.379 211.084 140.188 1.00 30.00 ? 344 LEU C CA   1 
ATOM 1082 C C    . LEU A 1 72 ? 205.887 209.751 140.738 1.00 30.00 ? 344 LEU C C    1 
ATOM 1083 O O    . LEU A 1 72 ? 205.522 209.369 141.849 1.00 30.00 ? 344 LEU C O    1 
ATOM 1084 C CB   . LEU A 1 72 ? 206.289 212.229 140.666 1.00 30.00 ? 344 LEU C CB   1 
ATOM 1085 C CG   . LEU A 1 72 ? 205.987 213.619 140.088 1.00 30.00 ? 344 LEU C CG   1 
ATOM 1086 C CD1  . LEU A 1 72 ? 206.913 214.644 140.735 1.00 30.00 ? 344 LEU C CD1  1 
ATOM 1087 C CD2  . LEU A 1 72 ? 206.222 213.676 138.581 1.00 30.00 ? 344 LEU C CD2  1 
ATOM 1088 H H    . LEU A 1 72 ? 203.764 210.908 141.548 1.00 30.00 ? 344 LEU C H    1 
ATOM 1089 H HA   . LEU A 1 72 ? 205.413 211.023 139.101 1.00 30.00 ? 344 LEU C HA   1 
ATOM 1090 H HB2  . LEU A 1 72 ? 206.217 212.284 141.751 1.00 30.00 ? 344 LEU C HB2  1 
ATOM 1091 H HB3  . LEU A 1 72 ? 207.321 211.981 140.424 1.00 30.00 ? 344 LEU C HB3  1 
ATOM 1092 H HG   . LEU A 1 72 ? 204.957 213.901 140.305 1.00 30.00 ? 344 LEU C HG   1 
ATOM 1093 H HD11 . LEU A 1 72 ? 206.667 215.640 140.373 1.00 30.00 ? 344 LEU C HD11 1 
ATOM 1094 H HD12 . LEU A 1 72 ? 207.950 214.417 140.496 1.00 30.00 ? 344 LEU C HD12 1 
ATOM 1095 H HD13 . LEU A 1 72 ? 206.782 214.624 141.815 1.00 30.00 ? 344 LEU C HD13 1 
ATOM 1096 H HD21 . LEU A 1 72 ? 207.234 213.357 138.342 1.00 30.00 ? 344 LEU C HD21 1 
ATOM 1097 H HD22 . LEU A 1 72 ? 205.517 213.027 138.070 1.00 30.00 ? 344 LEU C HD22 1 
ATOM 1098 H HD23 . LEU A 1 72 ? 206.073 214.693 138.226 1.00 30.00 ? 344 LEU C HD23 1 
ATOM 1099 N N    . ASP A 1 73 ? 206.719 209.029 139.990 1.00 30.00 ? 345 ASP C N    1 
ATOM 1100 C CA   . ASP A 1 73 ? 207.138 207.668 140.330 1.00 30.00 ? 345 ASP C CA   1 
ATOM 1101 C C    . ASP A 1 73 ? 208.441 207.284 139.608 1.00 30.00 ? 345 ASP C C    1 
ATOM 1102 O O    . ASP A 1 73 ? 208.475 207.238 138.379 1.00 30.00 ? 345 ASP C O    1 
ATOM 1103 C CB   . ASP A 1 73 ? 205.972 206.749 139.941 1.00 30.00 ? 345 ASP C CB   1 
ATOM 1104 C CG   . ASP A 1 73 ? 206.150 205.276 140.300 1.00 30.00 ? 345 ASP C CG   1 
ATOM 1105 O OD1  . ASP A 1 73 ? 207.254 204.841 140.680 1.00 30.00 ? 345 ASP C OD1  1 
ATOM 1106 O OD2  . ASP A 1 73 ? 205.167 204.514 140.184 1.00 30.00 ? 345 ASP C OD2  1 
ATOM 1107 H H    . ASP A 1 73 ? 207.013 209.397 139.099 1.00 30.00 ? 345 ASP C H    1 
ATOM 1108 H HA   . ASP A 1 73 ? 207.295 207.601 141.405 1.00 30.00 ? 345 ASP C HA   1 
ATOM 1109 H HB2  . ASP A 1 73 ? 205.075 207.108 140.440 1.00 30.00 ? 345 ASP C HB2  1 
ATOM 1110 H HB3  . ASP A 1 73 ? 205.794 206.828 138.872 1.00 30.00 ? 345 ASP C HB3  1 
ATOM 1111 N N    . PHE A 1 74 ? 209.512 207.005 140.354 1.00 30.00 ? 346 PHE C N    1 
ATOM 1112 C CA   . PHE A 1 74 ? 210.849 206.685 139.829 1.00 30.00 ? 346 PHE C CA   1 
ATOM 1113 C C    . PHE A 1 74 ? 211.405 205.405 140.468 1.00 30.00 ? 346 PHE C C    1 
ATOM 1114 O O    . PHE A 1 74 ? 211.276 205.216 141.675 1.00 30.00 ? 346 PHE C O    1 
ATOM 1115 C CB   . PHE A 1 74 ? 211.812 207.861 140.081 1.00 30.00 ? 346 PHE C CB   1 
ATOM 1116 C CG   . PHE A 1 74 ? 211.312 209.257 139.733 1.00 30.00 ? 346 PHE C CG   1 
ATOM 1117 C CD1  . PHE A 1 74 ? 210.754 209.529 138.472 1.00 30.00 ? 346 PHE C CD1  1 
ATOM 1118 C CD2  . PHE A 1 74 ? 211.453 210.309 140.662 1.00 30.00 ? 346 PHE C CD2  1 
ATOM 1119 C CE1  . PHE A 1 74 ? 210.324 210.827 138.160 1.00 30.00 ? 346 PHE C CE1  1 
ATOM 1120 C CE2  . PHE A 1 74 ? 211.031 211.611 140.346 1.00 30.00 ? 346 PHE C CE2  1 
ATOM 1121 C CZ   . PHE A 1 74 ? 210.469 211.869 139.089 1.00 30.00 ? 346 PHE C CZ   1 
ATOM 1122 H H    . PHE A 1 74 ? 209.402 207.015 141.357 1.00 30.00 ? 346 PHE C H    1 
ATOM 1123 H HA   . PHE A 1 74 ? 210.792 206.525 138.754 1.00 30.00 ? 346 PHE C HA   1 
ATOM 1124 H HB2  . PHE A 1 74 ? 212.087 207.849 141.132 1.00 30.00 ? 346 PHE C HB2  1 
ATOM 1125 H HB3  . PHE A 1 74 ? 212.721 207.685 139.512 1.00 30.00 ? 346 PHE C HB3  1 
ATOM 1126 H HD1  . PHE A 1 74 ? 210.655 208.744 137.740 1.00 30.00 ? 346 PHE C HD1  1 
ATOM 1127 H HD2  . PHE A 1 74 ? 211.899 210.113 141.622 1.00 30.00 ? 346 PHE C HD2  1 
ATOM 1128 H HE1  . PHE A 1 74 ? 209.900 211.027 137.189 1.00 30.00 ? 346 PHE C HE1  1 
ATOM 1129 H HE2  . PHE A 1 74 ? 211.148 212.410 141.060 1.00 30.00 ? 346 PHE C HE2  1 
ATOM 1130 H HZ   . PHE A 1 74 ? 210.149 212.868 138.839 1.00 30.00 ? 346 PHE C HZ   1 
ATOM 1131 N N    . LYS A 1 75 ? 212.052 204.532 139.689 1.00 30.00 ? 347 LYS C N    1 
ATOM 1132 C CA   . LYS A 1 75 ? 212.600 203.246 140.142 1.00 30.00 ? 347 LYS C CA   1 
ATOM 1133 C C    . LYS A 1 75 ? 213.899 202.922 139.412 1.00 30.00 ? 347 LYS C C    1 
ATOM 1134 O O    . LYS A 1 75 ? 214.055 203.298 138.256 1.00 30.00 ? 347 LYS C O    1 
ATOM 1135 C CB   . LYS A 1 75 ? 211.589 202.122 139.880 1.00 30.00 ? 347 LYS C CB   1 
ATOM 1136 C CG   . LYS A 1 75 ? 210.226 202.320 140.560 1.00 30.00 ? 347 LYS C CG   1 
ATOM 1137 C CD   . LYS A 1 75 ? 209.340 201.086 140.349 1.00 30.00 ? 347 LYS C CD   1 
ATOM 1138 C CE   . LYS A 1 75 ? 207.936 201.232 140.945 1.00 30.00 ? 347 LYS C CE   1 
ATOM 1139 N NZ   . LYS A 1 75 ? 207.090 202.171 140.177 1.00 30.00 ? 347 LYS C NZ   1 
ATOM 1140 H H    . LYS A 1 75 ? 212.167 204.767 138.717 1.00 30.00 ? 347 LYS C H    1 
ATOM 1141 H HA   . LYS A 1 75 ? 212.819 203.284 141.208 1.00 30.00 ? 347 LYS C HA   1 
ATOM 1142 H HB2  . LYS A 1 75 ? 211.428 202.023 138.809 1.00 30.00 ? 347 LYS C HB2  1 
ATOM 1143 H HB3  . LYS A 1 75 ? 212.016 201.188 140.241 1.00 30.00 ? 347 LYS C HB3  1 
ATOM 1144 H HG2  . LYS A 1 75 ? 210.366 202.473 141.628 1.00 30.00 ? 347 LYS C HG2  1 
ATOM 1145 H HG3  . LYS A 1 75 ? 209.730 203.188 140.130 1.00 30.00 ? 347 LYS C HG3  1 
ATOM 1146 H HD2  . LYS A 1 75 ? 209.249 200.870 139.287 1.00 30.00 ? 347 LYS C HD2  1 
ATOM 1147 H HD3  . LYS A 1 75 ? 209.828 200.239 140.827 1.00 30.00 ? 347 LYS C HD3  1 
ATOM 1148 H HE2  . LYS A 1 75 ? 207.465 200.250 140.939 1.00 30.00 ? 347 LYS C HE2  1 
ATOM 1149 H HE3  . LYS A 1 75 ? 208.020 201.558 141.979 1.00 30.00 ? 347 LYS C HE3  1 
ATOM 1150 H HZ1  . LYS A 1 75 ? 206.140 202.160 140.511 1.00 30.00 ? 347 LYS C HZ1  1 
ATOM 1151 H HZ2  . LYS A 1 75 ? 207.074 201.950 139.195 1.00 30.00 ? 347 LYS C HZ2  1 
ATOM 1152 H HZ3  . LYS A 1 75 ? 207.392 203.125 140.297 1.00 30.00 ? 347 LYS C HZ3  1 
ATOM 1153 N N    . ASP A 1 76 ? 214.802 202.179 140.049 1.00 30.00 ? 348 ASP C N    1 
ATOM 1154 C CA   . ASP A 1 76 ? 216.090 201.701 139.504 1.00 30.00 ? 348 ASP C CA   1 
ATOM 1155 C C    . ASP A 1 76 ? 216.508 200.369 140.161 1.00 30.00 ? 348 ASP C C    1 
ATOM 1156 O O    . ASP A 1 76 ? 216.094 200.114 141.288 1.00 30.00 ? 348 ASP C O    1 
ATOM 1157 C CB   . ASP A 1 76 ? 217.204 202.737 139.740 1.00 30.00 ? 348 ASP C CB   1 
ATOM 1158 C CG   . ASP A 1 76 ? 216.895 204.143 139.213 1.00 30.00 ? 348 ASP C CG   1 
ATOM 1159 O OD1  . ASP A 1 76 ? 217.089 204.388 138.003 1.00 30.00 ? 348 ASP C OD1  1 
ATOM 1160 O OD2  . ASP A 1 76 ? 216.504 205.028 140.007 1.00 30.00 ? 348 ASP C OD2  1 
ATOM 1161 H H    . ASP A 1 76 ? 214.578 201.882 140.986 1.00 30.00 ? 348 ASP C H    1 
ATOM 1162 H HA   . ASP A 1 76 ? 215.991 201.532 138.434 1.00 30.00 ? 348 ASP C HA   1 
ATOM 1163 H HB2  . ASP A 1 76 ? 217.397 202.794 140.810 1.00 30.00 ? 348 ASP C HB2  1 
ATOM 1164 H HB3  . ASP A 1 76 ? 218.118 202.381 139.268 1.00 30.00 ? 348 ASP C HB3  1 
ATOM 1165 N N    . ARG A 1 77 ? 217.332 199.532 139.511 1.00 30.00 ? 349 ARG C N    1 
ATOM 1166 C CA   . ARG A 1 77 ? 217.996 198.367 140.132 1.00 30.00 ? 349 ARG C CA   1 
ATOM 1167 C C    . ARG A 1 77 ? 219.256 197.921 139.381 1.00 30.00 ? 349 ARG C C    1 
ATOM 1168 O O    . ARG A 1 77 ? 219.383 198.170 138.188 1.00 30.00 ? 349 ARG C O    1 
ATOM 1169 C CB   . ARG A 1 77 ? 216.995 197.222 140.327 1.00 30.00 ? 349 ARG C CB   1 
ATOM 1170 C CG   . ARG A 1 77 ? 216.355 196.697 139.039 1.00 30.00 ? 349 ARG C CG   1 
ATOM 1171 C CD   . ARG A 1 77 ? 215.083 195.886 139.315 1.00 30.00 ? 349 ARG C CD   1 
ATOM 1172 N NE   . ARG A 1 77 ? 213.939 196.763 139.620 1.00 30.00 ? 349 ARG C NE   1 
ATOM 1173 C CZ   . ARG A 1 77 ? 212.667 196.420 139.668 1.00 30.00 ? 349 ARG C CZ   1 
ATOM 1174 N NH1  . ARG A 1 77 ? 211.754 197.320 139.869 1.00 30.00 ? 349 ARG C NH1  1 
ATOM 1175 N NH2  . ARG A 1 77 ? 212.271 195.194 139.513 1.00 30.00 ? 349 ARG C NH2  1 
ATOM 1176 H H    . ARG A 1 77 ? 217.629 199.788 138.582 1.00 30.00 ? 349 ARG C H    1 
ATOM 1177 H HA   . ARG A 1 77 ? 218.333 198.672 141.122 1.00 30.00 ? 349 ARG C HA   1 
ATOM 1178 H HB2  . ARG A 1 77 ? 217.493 196.394 140.828 1.00 30.00 ? 349 ARG C HB2  1 
ATOM 1179 H HB3  . ARG A 1 77 ? 216.210 197.568 140.997 1.00 30.00 ? 349 ARG C HB3  1 
ATOM 1180 H HG2  . ARG A 1 77 ? 216.096 197.511 138.368 1.00 30.00 ? 349 ARG C HG2  1 
ATOM 1181 H HG3  . ARG A 1 77 ? 217.079 196.064 138.533 1.00 30.00 ? 349 ARG C HG3  1 
ATOM 1182 H HD2  . ARG A 1 77 ? 214.857 195.307 138.422 1.00 30.00 ? 349 ARG C HD2  1 
ATOM 1183 H HD3  . ARG A 1 77 ? 215.264 195.199 140.138 1.00 30.00 ? 349 ARG C HD3  1 
ATOM 1184 H HE   . ARG A 1 77 ? 214.139 197.734 139.780 1.00 30.00 ? 349 ARG C HE   1 
ATOM 1185 H HH11 . ARG A 1 77 ? 210.783 197.057 139.872 1.00 30.00 ? 349 ARG C HH11 1 
ATOM 1186 H HH12 . ARG A 1 77 ? 212.013 198.286 139.980 1.00 30.00 ? 349 ARG C HH12 1 
ATOM 1187 H HH21 . ARG A 1 77 ? 211.292 194.961 139.572 1.00 30.00 ? 349 ARG C HH21 1 
ATOM 1188 H HH22 . ARG A 1 77 ? 212.962 194.474 139.374 1.00 30.00 ? 349 ARG C HH22 1 
ATOM 1189 N N    . VAL A 1 78 ? 220.182 197.244 140.061 1.00 30.00 ? 350 VAL C N    1 
ATOM 1190 C CA   . VAL A 1 78 ? 221.526 196.876 139.559 1.00 30.00 ? 350 VAL C CA   1 
ATOM 1191 C C    . VAL A 1 78 ? 221.965 195.511 140.127 1.00 30.00 ? 350 VAL C C    1 
ATOM 1192 O O    . VAL A 1 78 ? 221.677 195.211 141.282 1.00 30.00 ? 350 VAL C O    1 
ATOM 1193 C CB   . VAL A 1 78 ? 222.567 197.967 139.931 1.00 30.00 ? 350 VAL C CB   1 
ATOM 1194 C CG1  . VAL A 1 78 ? 223.963 197.660 139.378 1.00 30.00 ? 350 VAL C CG1  1 
ATOM 1195 C CG2  . VAL A 1 78 ? 222.191 199.361 139.428 1.00 30.00 ? 350 VAL C CG2  1 
ATOM 1196 H H    . VAL A 1 78 ? 219.972 197.017 141.022 1.00 30.00 ? 350 VAL C H    1 
ATOM 1197 H HA   . VAL A 1 78 ? 221.494 196.799 138.473 1.00 30.00 ? 350 VAL C HA   1 
ATOM 1198 H HB   . VAL A 1 78 ? 222.644 198.020 141.016 1.00 30.00 ? 350 VAL C HB   1 
ATOM 1199 H HG11 . VAL A 1 78 ? 224.635 198.488 139.590 1.00 30.00 ? 350 VAL C HG11 1 
ATOM 1200 H HG12 . VAL A 1 78 ? 224.383 196.778 139.851 1.00 30.00 ? 350 VAL C HG12 1 
ATOM 1201 H HG13 . VAL A 1 78 ? 223.912 197.515 138.303 1.00 30.00 ? 350 VAL C HG13 1 
ATOM 1202 H HG21 . VAL A 1 78 ? 222.970 200.077 139.679 1.00 30.00 ? 350 VAL C HG21 1 
ATOM 1203 H HG22 . VAL A 1 78 ? 221.271 199.696 139.897 1.00 30.00 ? 350 VAL C HG22 1 
ATOM 1204 H HG23 . VAL A 1 78 ? 222.064 199.342 138.351 1.00 30.00 ? 350 VAL C HG23 1 
ATOM 1205 N N    . GLN A 1 79 ? 222.707 194.699 139.372 1.00 30.00 ? 351 GLN C N    1 
ATOM 1206 C CA   . GLN A 1 79 ? 223.254 193.406 139.807 1.00 30.00 ? 351 GLN C CA   1 
ATOM 1207 C C    . GLN A 1 79 ? 224.660 193.208 139.229 1.00 30.00 ? 351 GLN C C    1 
ATOM 1208 O O    . GLN A 1 79 ? 224.952 193.722 138.156 1.00 30.00 ? 351 GLN C O    1 
ATOM 1209 C CB   . GLN A 1 79 ? 222.353 192.240 139.366 1.00 30.00 ? 351 GLN C CB   1 
ATOM 1210 C CG   . GLN A 1 79 ? 220.905 192.234 139.901 1.00 30.00 ? 351 GLN C CG   1 
ATOM 1211 C CD   . GLN A 1 79 ? 219.846 193.002 139.100 1.00 30.00 ? 351 GLN C CD   1 
ATOM 1212 O OE1  . GLN A 1 79 ? 218.705 193.144 139.512 1.00 30.00 ? 351 GLN C OE1  1 
ATOM 1213 N NE2  . GLN A 1 79 ? 220.130 193.507 137.927 1.00 30.00 ? 351 GLN C NE2  1 
ATOM 1214 H H    . GLN A 1 79 ? 223.001 195.033 138.468 1.00 30.00 ? 351 GLN C H    1 
ATOM 1215 H HA   . GLN A 1 79 ? 223.332 193.388 140.893 1.00 30.00 ? 351 GLN C HA   1 
ATOM 1216 H HB2  . GLN A 1 79 ? 222.353 192.164 138.280 1.00 30.00 ? 351 GLN C HB2  1 
ATOM 1217 H HB3  . GLN A 1 79 ? 222.822 191.330 139.735 1.00 30.00 ? 351 GLN C HB3  1 
ATOM 1218 H HG2  . GLN A 1 79 ? 220.576 191.198 139.919 1.00 30.00 ? 351 GLN C HG2  1 
ATOM 1219 H HG3  . GLN A 1 79 ? 220.910 192.590 140.928 1.00 30.00 ? 351 GLN C HG3  1 
ATOM 1220 H HE21 . GLN A 1 79 ? 221.045 193.384 137.525 1.00 30.00 ? 351 GLN C HE21 1 
ATOM 1221 H HE22 . GLN A 1 79 ? 219.392 193.976 137.426 1.00 30.00 ? 351 GLN C HE22 1 
ATOM 1222 N N    . SER A 1 80 ? 225.540 192.454 139.890 1.00 30.00 ? 352 SER C N    1 
ATOM 1223 C CA   . SER A 1 80 ? 226.923 192.215 139.431 1.00 30.00 ? 352 SER C CA   1 
ATOM 1224 C C    . SER A 1 80 ? 227.535 190.935 140.008 1.00 30.00 ? 352 SER C C    1 
ATOM 1225 O O    . SER A 1 80 ? 227.138 190.521 141.093 1.00 30.00 ? 352 SER C O    1 
ATOM 1226 C CB   . SER A 1 80 ? 227.775 193.416 139.834 1.00 30.00 ? 352 SER C CB   1 
ATOM 1227 O OG   . SER A 1 80 ? 229.080 193.287 139.329 1.00 30.00 ? 352 SER C OG   1 
ATOM 1228 H H    . SER A 1 80 ? 225.263 192.039 140.767 1.00 30.00 ? 352 SER C H    1 
ATOM 1229 H HA   . SER A 1 80 ? 226.939 192.130 138.346 1.00 30.00 ? 352 SER C HA   1 
ATOM 1230 H HB2  . SER A 1 80 ? 227.327 194.327 139.442 1.00 30.00 ? 352 SER C HB2  1 
ATOM 1231 H HB3  . SER A 1 80 ? 227.812 193.484 140.920 1.00 30.00 ? 352 SER C HB3  1 
ATOM 1232 H HG   . SER A 1 80 ? 229.558 194.092 139.506 1.00 30.00 ? 352 SER C HG   1 
ATOM 1233 N N    . LYS A 1 81 ? 228.501 190.302 139.327 1.00 30.00 ? 353 LYS C N    1 
ATOM 1234 C CA   . LYS A 1 81 ? 229.191 189.068 139.747 1.00 30.00 ? 353 LYS C CA   1 
ATOM 1235 C C    . LYS A 1 81 ? 230.644 189.041 139.246 1.00 30.00 ? 353 LYS C C    1 
ATOM 1236 O O    . LYS A 1 81 ? 230.943 189.644 138.219 1.00 30.00 ? 353 LYS C O    1 
ATOM 1237 C CB   . LYS A 1 81 ? 228.428 187.829 139.247 1.00 30.00 ? 353 LYS C CB   1 
ATOM 1238 C CG   . LYS A 1 81 ? 227.026 187.595 139.846 1.00 30.00 ? 353 LYS C CG   1 
ATOM 1239 C CD   . LYS A 1 81 ? 225.837 188.113 139.011 1.00 30.00 ? 353 LYS C CD   1 
ATOM 1240 C CE   . LYS A 1 81 ? 224.534 187.900 139.789 1.00 30.00 ? 353 LYS C CE   1 
ATOM 1241 N NZ   . LYS A 1 81 ? 223.329 188.090 138.949 1.00 30.00 ? 353 LYS C NZ   1 
ATOM 1242 H H    . LYS A 1 81 ? 228.823 190.738 138.478 1.00 30.00 ? 353 LYS C H    1 
ATOM 1243 H HA   . LYS A 1 81 ? 229.234 189.033 140.835 1.00 30.00 ? 353 LYS C HA   1 
ATOM 1244 H HB2  . LYS A 1 81 ? 228.355 187.865 138.162 1.00 30.00 ? 353 LYS C HB2  1 
ATOM 1245 H HB3  . LYS A 1 81 ? 229.027 186.958 139.505 1.00 30.00 ? 353 LYS C HB3  1 
ATOM 1246 H HG2  . LYS A 1 81 ? 226.883 186.522 139.948 1.00 30.00 ? 353 LYS C HG2  1 
ATOM 1247 H HG3  . LYS A 1 81 ? 226.998 188.008 140.852 1.00 30.00 ? 353 LYS C HG3  1 
ATOM 1248 H HD2  . LYS A 1 81 ? 225.956 189.171 138.781 1.00 30.00 ? 353 LYS C HD2  1 
ATOM 1249 H HD3  . LYS A 1 81 ? 225.804 187.559 138.074 1.00 30.00 ? 353 LYS C HD3  1 
ATOM 1250 H HE2  . LYS A 1 81 ? 224.534 186.887 140.185 1.00 30.00 ? 353 LYS C HE2  1 
ATOM 1251 H HE3  . LYS A 1 81 ? 224.524 188.586 140.634 1.00 30.00 ? 353 LYS C HE3  1 
ATOM 1252 H HZ1  . LYS A 1 81 ? 223.303 187.405 138.211 1.00 30.00 ? 353 LYS C HZ1  1 
ATOM 1253 H HZ2  . LYS A 1 81 ? 223.314 189.002 138.525 1.00 30.00 ? 353 LYS C HZ2  1 
ATOM 1254 H HZ3  . LYS A 1 81 ? 222.487 187.978 139.490 1.00 30.00 ? 353 LYS C HZ3  1 
ATOM 1255 N N    . ILE A 1 82 ? 231.542 188.332 139.937 1.00 30.00 ? 354 ILE C N    1 
ATOM 1256 C CA   . ILE A 1 82 ? 232.971 188.162 139.578 1.00 30.00 ? 354 ILE C CA   1 
ATOM 1257 C C    . ILE A 1 82 ? 233.379 186.683 139.683 1.00 30.00 ? 354 ILE C C    1 
ATOM 1258 O O    . ILE A 1 82 ? 232.957 185.988 140.603 1.00 30.00 ? 354 ILE C O    1 
ATOM 1259 C CB   . ILE A 1 82 ? 233.881 189.095 140.420 1.00 30.00 ? 354 ILE C CB   1 
ATOM 1260 C CG1  . ILE A 1 82 ? 233.553 190.575 140.119 1.00 30.00 ? 354 ILE C CG1  1 
ATOM 1261 C CG2  . ILE A 1 82 ? 235.376 188.828 140.163 1.00 30.00 ? 354 ILE C CG2  1 
ATOM 1262 C CD1  . ILE A 1 82 ? 234.289 191.591 140.991 1.00 30.00 ? 354 ILE C CD1  1 
ATOM 1263 H H    . ILE A 1 82 ? 231.212 187.840 140.753 1.00 30.00 ? 354 ILE C H    1 
ATOM 1264 H HA   . ILE A 1 82 ? 233.099 188.440 138.533 1.00 30.00 ? 354 ILE C HA   1 
ATOM 1265 H HB   . ILE A 1 82 ? 233.681 188.902 141.473 1.00 30.00 ? 354 ILE C HB   1 
ATOM 1266 H HG12 . ILE A 1 82 ? 233.770 190.787 139.075 1.00 30.00 ? 354 ILE C HG12 1 
ATOM 1267 H HG13 . ILE A 1 82 ? 232.491 190.744 140.284 1.00 30.00 ? 354 ILE C HG13 1 
ATOM 1268 H HG21 . ILE A 1 82 ? 235.635 187.805 140.420 1.00 30.00 ? 354 ILE C HG21 1 
ATOM 1269 H HG22 . ILE A 1 82 ? 235.997 189.467 140.784 1.00 30.00 ? 354 ILE C HG22 1 
ATOM 1270 H HG23 . ILE A 1 82 ? 235.615 189.010 139.120 1.00 30.00 ? 354 ILE C HG23 1 
ATOM 1271 H HD11 . ILE A 1 82 ? 235.351 191.590 140.764 1.00 30.00 ? 354 ILE C HD11 1 
ATOM 1272 H HD12 . ILE A 1 82 ? 233.898 192.582 140.784 1.00 30.00 ? 354 ILE C HD12 1 
ATOM 1273 H HD13 . ILE A 1 82 ? 234.138 191.364 142.040 1.00 30.00 ? 354 ILE C HD13 1 
ATOM 1274 N N    . GLY A 1 83 ? 234.176 186.184 138.732 1.00 30.00 ? 355 GLY C N    1 
ATOM 1275 C CA   . GLY A 1 83 ? 234.338 184.753 138.443 1.00 30.00 ? 355 GLY C CA   1 
ATOM 1276 C C    . GLY A 1 83 ? 235.514 184.020 139.094 1.00 30.00 ? 355 GLY C C    1 
ATOM 1277 O O    . GLY A 1 83 ? 236.072 184.446 140.094 1.00 30.00 ? 355 GLY C O    1 
ATOM 1278 H H    . GLY A 1 83 ? 234.530 186.828 138.042 1.00 30.00 ? 355 GLY C H    1 
ATOM 1279 H HA2  . GLY A 1 83 ? 233.428 184.225 138.718 1.00 30.00 ? 355 GLY C HA2  1 
ATOM 1280 H HA3  . GLY A 1 83 ? 234.436 184.644 137.365 1.00 30.00 ? 355 GLY C HA3  1 
ATOM 1281 N N    . SER A 1 84 ? 235.884 182.887 138.506 1.00 30.00 ? 356 SER C N    1 
ATOM 1282 C CA   . SER A 1 84 ? 236.933 181.957 138.960 1.00 30.00 ? 356 SER C CA   1 
ATOM 1283 C C    . SER A 1 84 ? 238.364 182.423 138.631 1.00 30.00 ? 356 SER C C    1 
ATOM 1284 O O    . SER A 1 84 ? 239.123 181.727 137.959 1.00 30.00 ? 356 SER C O    1 
ATOM 1285 C CB   . SER A 1 84 ? 236.628 180.575 138.368 1.00 30.00 ? 356 SER C CB   1 
ATOM 1286 O OG   . SER A 1 84 ? 237.600 179.627 138.745 1.00 30.00 ? 356 SER C OG   1 
ATOM 1287 H H    . SER A 1 84 ? 235.352 182.615 137.695 1.00 30.00 ? 356 SER C H    1 
ATOM 1288 H HA   . SER A 1 84 ? 236.871 181.869 140.044 1.00 30.00 ? 356 SER C HA   1 
ATOM 1289 H HB2  . SER A 1 84 ? 235.655 180.240 138.721 1.00 30.00 ? 356 SER C HB2  1 
ATOM 1290 H HB3  . SER A 1 84 ? 236.598 180.648 137.284 1.00 30.00 ? 356 SER C HB3  1 
ATOM 1291 H HG   . SER A 1 84 ? 238.437 179.951 138.408 1.00 30.00 ? 356 SER C HG   1 
ATOM 1292 N N    . LEU A 1 85 ? 238.738 183.625 139.061 1.00 30.00 ? 357 LEU C N    1 
ATOM 1293 C CA   . LEU A 1 85 ? 240.026 184.242 138.725 1.00 30.00 ? 357 LEU C CA   1 
ATOM 1294 C C    . LEU A 1 85 ? 241.196 183.434 139.305 1.00 30.00 ? 357 LEU C C    1 
ATOM 1295 O O    . LEU A 1 85 ? 241.168 183.064 140.471 1.00 30.00 ? 357 LEU C O    1 
ATOM 1296 C CB   . LEU A 1 85 ? 240.057 185.703 139.213 1.00 30.00 ? 357 LEU C CB   1 
ATOM 1297 C CG   . LEU A 1 85 ? 238.864 186.570 138.764 1.00 30.00 ? 357 LEU C CG   1 
ATOM 1298 C CD1  . LEU A 1 85 ? 239.069 188.013 139.201 1.00 30.00 ? 357 LEU C CD1  1 
ATOM 1299 C CD2  . LEU A 1 85 ? 238.656 186.573 137.254 1.00 30.00 ? 357 LEU C CD2  1 
ATOM 1300 H H    . LEU A 1 85 ? 238.079 184.142 139.620 1.00 30.00 ? 357 LEU C H    1 
ATOM 1301 H HA   . LEU A 1 85 ? 240.127 184.250 137.640 1.00 30.00 ? 357 LEU C HA   1 
ATOM 1302 H HB2  . LEU A 1 85 ? 240.083 185.704 140.302 1.00 30.00 ? 357 LEU C HB2  1 
ATOM 1303 H HB3  . LEU A 1 85 ? 240.983 186.159 138.865 1.00 30.00 ? 357 LEU C HB3  1 
ATOM 1304 H HG   . LEU A 1 85 ? 237.953 186.209 139.236 1.00 30.00 ? 357 LEU C HG   1 
ATOM 1305 H HD11 . LEU A 1 85 ? 238.196 188.596 138.929 1.00 30.00 ? 357 LEU C HD11 1 
ATOM 1306 H HD12 . LEU A 1 85 ? 239.952 188.433 138.730 1.00 30.00 ? 357 LEU C HD12 1 
ATOM 1307 H HD13 . LEU A 1 85 ? 239.194 188.057 140.276 1.00 30.00 ? 357 LEU C HD13 1 
ATOM 1308 H HD21 . LEU A 1 85 ? 239.547 186.931 136.750 1.00 30.00 ? 357 LEU C HD21 1 
ATOM 1309 H HD22 . LEU A 1 85 ? 238.412 185.576 136.906 1.00 30.00 ? 357 LEU C HD22 1 
ATOM 1310 H HD23 . LEU A 1 85 ? 237.822 187.221 137.009 1.00 30.00 ? 357 LEU C HD23 1 
ATOM 1311 N N    . ASP A 1 86 ? 242.224 183.154 138.513 1.00 30.00 ? 358 ASP C N    1 
ATOM 1312 C CA   . ASP A 1 86 ? 243.318 182.237 138.868 1.00 30.00 ? 358 ASP C CA   1 
ATOM 1313 C C    . ASP A 1 86 ? 244.673 182.767 138.377 1.00 30.00 ? 358 ASP C C    1 
ATOM 1314 O O    . ASP A 1 86 ? 244.771 183.297 137.273 1.00 30.00 ? 358 ASP C O    1 
ATOM 1315 C CB   . ASP A 1 86 ? 242.979 180.852 138.279 1.00 30.00 ? 358 ASP C CB   1 
ATOM 1316 C CG   . ASP A 1 86 ? 243.867 179.677 138.715 1.00 30.00 ? 358 ASP C CG   1 
ATOM 1317 O OD1  . ASP A 1 86 ? 244.945 179.883 139.299 1.00 30.00 ? 358 ASP C OD1  1 
ATOM 1318 O OD2  . ASP A 1 86 ? 243.464 178.518 138.479 1.00 30.00 ? 358 ASP C OD2  1 
ATOM 1319 H H    . ASP A 1 86 ? 242.220 183.529 137.580 1.00 30.00 ? 358 ASP C H    1 
ATOM 1320 H HA   . ASP A 1 86 ? 243.374 182.133 139.950 1.00 30.00 ? 358 ASP C HA   1 
ATOM 1321 H HB2  . ASP A 1 86 ? 241.956 180.612 138.559 1.00 30.00 ? 358 ASP C HB2  1 
ATOM 1322 H HB3  . ASP A 1 86 ? 243.001 180.919 137.194 1.00 30.00 ? 358 ASP C HB3  1 
ATOM 1323 N N    . ASN A 1 87 ? 245.730 182.615 139.174 1.00 30.00 ? 359 ASN C N    1 
ATOM 1324 C CA   . ASN A 1 87 ? 247.122 182.812 138.759 1.00 30.00 ? 359 ASN C CA   1 
ATOM 1325 C C    . ASN A 1 87 ? 248.091 181.913 139.547 1.00 30.00 ? 359 ASN C C    1 
ATOM 1326 O O    . ASN A 1 87 ? 247.850 181.571 140.698 1.00 30.00 ? 359 ASN C O    1 
ATOM 1327 C CB   . ASN A 1 87 ? 247.506 184.306 138.801 1.00 30.00 ? 359 ASN C CB   1 
ATOM 1328 C CG   . ASN A 1 87 ? 246.987 185.069 140.006 1.00 30.00 ? 359 ASN C CG   1 
ATOM 1329 O OD1  . ASN A 1 87 ? 247.588 185.076 141.069 1.00 30.00 ? 359 ASN C OD1  1 
ATOM 1330 N ND2  . ASN A 1 87 ? 245.874 185.748 139.885 1.00 30.00 ? 359 ASN C ND2  1 
ATOM 1331 H H    . ASN A 1 87 ? 245.589 182.124 140.043 1.00 30.00 ? 359 ASN C H    1 
ATOM 1332 H HA   . ASN A 1 87 ? 247.204 182.493 137.721 1.00 30.00 ? 359 ASN C HA   1 
ATOM 1333 H HB2  . ASN A 1 87 ? 248.589 184.402 138.778 1.00 30.00 ? 359 ASN C HB2  1 
ATOM 1334 H HB3  . ASN A 1 87 ? 247.113 184.783 137.905 1.00 30.00 ? 359 ASN C HB3  1 
ATOM 1335 H HD21 . ASN A 1 87 ? 245.367 185.777 139.016 1.00 30.00 ? 359 ASN C HD21 1 
ATOM 1336 H HD22 . ASN A 1 87 ? 245.528 186.227 140.699 1.00 30.00 ? 359 ASN C HD22 1 
ATOM 1337 N N    . ILE A 1 88 ? 249.207 181.561 138.921 1.00 30.00 ? 360 ILE C N    1 
ATOM 1338 C CA   . ILE A 1 88 ? 250.264 180.660 139.405 1.00 30.00 ? 360 ILE C CA   1 
ATOM 1339 C C    . ILE A 1 88 ? 251.606 181.346 139.142 1.00 30.00 ? 360 ILE C C    1 
ATOM 1340 O O    . ILE A 1 88 ? 251.720 182.112 138.190 1.00 30.00 ? 360 ILE C O    1 
ATOM 1341 C CB   . ILE A 1 88 ? 250.155 179.286 138.684 1.00 30.00 ? 360 ILE C CB   1 
ATOM 1342 C CG1  . ILE A 1 88 ? 248.950 178.494 139.241 1.00 30.00 ? 360 ILE C CG1  1 
ATOM 1343 C CG2  . ILE A 1 88 ? 251.432 178.427 138.775 1.00 30.00 ? 360 ILE C CG2  1 
ATOM 1344 C CD1  . ILE A 1 88 ? 248.671 177.167 138.524 1.00 30.00 ? 360 ILE C CD1  1 
ATOM 1345 H H    . ILE A 1 88 ? 249.352 181.946 138.002 1.00 30.00 ? 360 ILE C H    1 
ATOM 1346 H HA   . ILE A 1 88 ? 250.169 180.506 140.479 1.00 30.00 ? 360 ILE C HA   1 
ATOM 1347 H HB   . ILE A 1 88 ? 249.973 179.480 137.629 1.00 30.00 ? 360 ILE C HB   1 
ATOM 1348 H HG12 . ILE A 1 88 ? 249.097 178.285 140.295 1.00 30.00 ? 360 ILE C HG12 1 
ATOM 1349 H HG13 . ILE A 1 88 ? 248.061 179.110 139.145 1.00 30.00 ? 360 ILE C HG13 1 
ATOM 1350 H HG21 . ILE A 1 88 ? 252.266 178.938 138.303 1.00 30.00 ? 360 ILE C HG21 1 
ATOM 1351 H HG22 . ILE A 1 88 ? 251.308 177.492 138.235 1.00 30.00 ? 360 ILE C HG22 1 
ATOM 1352 H HG23 . ILE A 1 88 ? 251.669 178.204 139.811 1.00 30.00 ? 360 ILE C HG23 1 
ATOM 1353 H HD11 . ILE A 1 88 ? 249.425 176.428 138.767 1.00 30.00 ? 360 ILE C HD11 1 
ATOM 1354 H HD12 . ILE A 1 88 ? 248.642 177.323 137.452 1.00 30.00 ? 360 ILE C HD12 1 
ATOM 1355 H HD13 . ILE A 1 88 ? 247.711 176.784 138.853 1.00 30.00 ? 360 ILE C HD13 1 
ATOM 1356 N N    . THR A 1 89 ? 252.635 181.056 139.936 1.00 30.00 ? 361 THR C N    1 
ATOM 1357 C CA   . THR A 1 89 ? 254.033 181.338 139.564 1.00 30.00 ? 361 THR C CA   1 
ATOM 1358 C C    . THR A 1 89 ? 254.872 180.070 139.690 1.00 30.00 ? 361 THR C C    1 
ATOM 1359 O O    . THR A 1 89 ? 254.703 179.304 140.635 1.00 30.00 ? 361 THR C O    1 
ATOM 1360 C CB   . THR A 1 89 ? 254.636 182.473 140.405 1.00 30.00 ? 361 THR C CB   1 
ATOM 1361 O OG1  . THR A 1 89 ? 253.870 183.645 140.286 1.00 30.00 ? 361 THR C OG1  1 
ATOM 1362 C CG2  . THR A 1 89 ? 256.047 182.843 139.963 1.00 30.00 ? 361 THR C CG2  1 
ATOM 1363 H H    . THR A 1 89 ? 252.480 180.425 140.706 1.00 30.00 ? 361 THR C H    1 
ATOM 1364 H HA   . THR A 1 89 ? 254.077 181.646 138.520 1.00 30.00 ? 361 THR C HA   1 
ATOM 1365 H HB   . THR A 1 89 ? 254.651 182.178 141.452 1.00 30.00 ? 361 THR C HB   1 
ATOM 1366 H HG1  . THR A 1 89 ? 253.015 183.442 140.658 1.00 30.00 ? 361 THR C HG1  1 
ATOM 1367 H HG21 . THR A 1 89 ? 256.367 183.736 140.493 1.00 30.00 ? 361 THR C HG21 1 
ATOM 1368 H HG22 . THR A 1 89 ? 256.738 182.041 140.203 1.00 30.00 ? 361 THR C HG22 1 
ATOM 1369 H HG23 . THR A 1 89 ? 256.066 183.037 138.896 1.00 30.00 ? 361 THR C HG23 1 
ATOM 1370 N N    . HIS A 1 90 ? 255.782 179.832 138.751 1.00 30.00 ? 362 HIS C N    1 
ATOM 1371 C CA   . HIS A 1 90 ? 256.652 178.649 138.696 1.00 30.00 ? 362 HIS C CA   1 
ATOM 1372 C C    . HIS A 1 90 ? 255.904 177.323 138.839 1.00 30.00 ? 362 HIS C C    1 
ATOM 1373 O O    . HIS A 1 90 ? 254.948 177.079 138.104 1.00 30.00 ? 362 HIS C O    1 
ATOM 1374 C CB   . HIS A 1 90 ? 257.782 178.762 139.722 1.00 30.00 ? 362 HIS C CB   1 
ATOM 1375 C CG   . HIS A 1 90 ? 258.918 177.809 139.462 1.00 30.00 ? 362 HIS C CG   1 
ATOM 1376 N ND1  . HIS A 1 90 ? 258.800 176.439 139.222 1.00 30.00 ? 362 HIS C ND1  1 
ATOM 1377 C CD2  . HIS A 1 90 ? 260.238 178.132 139.504 1.00 30.00 ? 362 HIS C CD2  1 
ATOM 1378 C CE1  . HIS A 1 90 ? 260.055 175.978 139.090 1.00 30.00 ? 362 HIS C CE1  1 
ATOM 1379 N NE2  . HIS A 1 90 ? 260.935 176.972 139.265 1.00 30.00 ? 362 HIS C NE2  1 
ATOM 1380 H H    . HIS A 1 90 ? 255.865 180.500 138.001 1.00 30.00 ? 362 HIS C H    1 
ATOM 1381 H HA   . HIS A 1 90 ? 257.116 178.621 137.713 1.00 30.00 ? 362 HIS C HA   1 
ATOM 1382 H HB2  . HIS A 1 90 ? 258.174 179.777 139.701 1.00 30.00 ? 362 HIS C HB2  1 
ATOM 1383 H HB3  . HIS A 1 90 ? 257.396 178.573 140.723 1.00 30.00 ? 362 HIS C HB3  1 
ATOM 1384 H HD2  . HIS A 1 90 ? 260.650 179.108 139.697 1.00 30.00 ? 362 HIS C HD2  1 
ATOM 1385 H HE1  . HIS A 1 90 ? 260.321 174.954 138.884 1.00 30.00 ? 362 HIS C HE1  1 
ATOM 1386 H HE2  . HIS A 1 90 ? 261.937 176.874 139.217 1.00 30.00 ? 362 HIS C HE2  1 
# 
