data_9MQI
# 
_entry.id   9MQI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MQI         pdb_00009mqi 10.2210/pdb9mqi/pdb 
WWPDB D_1000291538 ?            ?                   
EMDB  EMD-48525    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MQI 
_pdbx_database_status.recvd_initial_deposition_date   2025-01-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound
#020_E1
;
_pdbx_database_related.db_id          EMD-48525 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 aashish.manglik@ucsf.edu Aashish Manglik  ?  'principal investigator/group leader' 0000-0002-7173-3741 
5 bshoichet@gmail.com      Brian   Shoichet K. 'principal investigator/group leader' 0000-0002-6098-7367 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kim, J.Y.'       1 ? 
'Vigneron, S.F.'  2 ? 
'Billesbolle, C.' 3 ? 
'Manglik, A.'     4 ? 
'Shoichet, B.K.'  5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Docking 14 million virtual isoquinuclidines against the mu and kappa opioid receptors reveals dual antagonists-inverse agonists with reduced withdrawal effects.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2025.01.09.632033 
_citation.pdbx_database_id_PubMed   39868130 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Vigneron, S.F.'  1  0000-0003-2671-3044 
primary 'Ohno, S.'        2  0000-0002-2414-5066 
primary 'Braz, J.'        3  ?                   
primary 'Kim, J.Y.'       4  0000-0002-6816-5958 
primary 'Kweon, O.S.'     5  0000-0001-6588-3420 
primary 'Webb, C.'        6  0000-0003-2784-0408 
primary 'Billesbolle, C.' 7  0000-0001-8084-1552 
primary 'Bhardwaj, K.'    8  0009-0000-1769-0210 
primary 'Irwin, J.'       9  0000-0002-1195-6417 
primary 'Manglik, A.'     10 0000-0002-7173-3741 
primary 'Basbaum, A.I.'   11 0000-0002-1710-6333 
primary 'Ellman, J.A.'    12 0000-0001-9320-5512 
primary 'Shoichet, B.K.'  13 0000-0002-6098-7367 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Mu-type opioid receptor' 46081.359 1 ? ? ? ? 
2 polymer     man 'Nanobody 6M' 14418.919 1 ? ? ? ? 
3 polymer     man 'NabFab Heavy Chain' 25684.463 1 ? ? ? ? 
4 polymer     man 'NabFab Light Chain' 23258.783 1 ? ? ? ? 
5 non-polymer syn 
;methyl (1S,3R,4S,6S,8M)-2-[(1-ethyl-1H-pyrazol-4-yl)methyl]-8-(3-hydroxyphenyl)-3,4-dimethyl-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylate
;
395.495   1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'M-OR-1,MOR-1,Mu opiate receptor,Mu opioid receptor,MOP,hMOP' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DYKDDDDASIDMDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMIT
AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISID
YYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWY
WENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRLLSGSREKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT
IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQL
ENLEAETAPLP
;
;DYKDDDDASIDMDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMIT
AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISID
YYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWY
WENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRLLSGSREKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVT
IPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQL
ENLEAETAPLP
;
A ? 
2 'polypeptide(L)' no no 
;QRQLVESGGGLVQPGGSLRLSCAASGTIFRLYDMGWFRQAPGKEREGVASITSGGSTKYADSVKGRFTISRDNAKNTVYL
QMNSLEPEDTAVYYCNAEYRTGIWEELLDGWGKGTPVTVSSHHHHHHEPEA
;
;QRQLVESGGGLVQPGGSLRLSCAASGTIFRLYDMGWFRQAPGKEREGVASITSGGSTKYADSVKGRFTISRDNAKNTVYL
QMNSLEPEDTAVYYCNAEYRTGIWEELLDGWGKGTPVTVSSHHHHHHEPEA
;
C ? 
3 'polypeptide(L)' no no 
;EISEVQLVESGGGLVQPGGSLRLSCAASGFNFSYYSIHWVRQAPGKGLEWVAYISSSSSYTSYADSVKGRFTISADTSKN
TAYLQMNSLRAEDTAVYYCARGYQYWQYHASWYWNGGLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV
KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
;EISEVQLVESGGGLVQPGGSLRLSCAASGFNFSYYSIHWVRQAPGKGLEWVAYISSSSSYTSYADSVKGRFTISADTSKN
TAYLQMNSLRAEDTAVYYCARGYQYWQYHASWYWNGGLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV
KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
H ? 
4 'polypeptide(L)' no no 
;SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQ
PEDFATYYCQQSSSSLITFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQ
PEDFATYYCQQSSSSLITFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS
QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
# 
_pdbx_entity_nonpoly.entity_id   5 
_pdbx_entity_nonpoly.name        
;methyl (1S,3R,4S,6S,8M)-2-[(1-ethyl-1H-pyrazol-4-yl)methyl]-8-(3-hydroxyphenyl)-3,4-dimethyl-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylate
;
_pdbx_entity_nonpoly.comp_id     A1BNM 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   TYR n 
1 3   LYS n 
1 4   ASP n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   ALA n 
1 9   SER n 
1 10  ILE n 
1 11  ASP n 
1 12  MET n 
1 13  ASP n 
1 14  SER n 
1 15  SER n 
1 16  ALA n 
1 17  ALA n 
1 18  PRO n 
1 19  THR n 
1 20  ASN n 
1 21  ALA n 
1 22  SER n 
1 23  ASN n 
1 24  CYS n 
1 25  THR n 
1 26  ASP n 
1 27  ALA n 
1 28  LEU n 
1 29  ALA n 
1 30  TYR n 
1 31  SER n 
1 32  SER n 
1 33  CYS n 
1 34  SER n 
1 35  PRO n 
1 36  ALA n 
1 37  PRO n 
1 38  SER n 
1 39  PRO n 
1 40  GLY n 
1 41  SER n 
1 42  TRP n 
1 43  VAL n 
1 44  ASN n 
1 45  LEU n 
1 46  SER n 
1 47  HIS n 
1 48  LEU n 
1 49  ASP n 
1 50  GLY n 
1 51  ASN n 
1 52  LEU n 
1 53  SER n 
1 54  ASP n 
1 55  PRO n 
1 56  CYS n 
1 57  GLY n 
1 58  PRO n 
1 59  ASN n 
1 60  ARG n 
1 61  THR n 
1 62  ASP n 
1 63  LEU n 
1 64  GLY n 
1 65  GLY n 
1 66  ARG n 
1 67  ASP n 
1 68  SER n 
1 69  LEU n 
1 70  CYS n 
1 71  PRO n 
1 72  PRO n 
1 73  THR n 
1 74  GLY n 
1 75  SER n 
1 76  PRO n 
1 77  SER n 
1 78  MET n 
1 79  ILE n 
1 80  THR n 
1 81  ALA n 
1 82  ILE n 
1 83  THR n 
1 84  ILE n 
1 85  MET n 
1 86  ALA n 
1 87  LEU n 
1 88  TYR n 
1 89  SER n 
1 90  ILE n 
1 91  VAL n 
1 92  CYS n 
1 93  VAL n 
1 94  VAL n 
1 95  GLY n 
1 96  LEU n 
1 97  PHE n 
1 98  GLY n 
1 99  ASN n 
1 100 PHE n 
1 101 LEU n 
1 102 VAL n 
1 103 MET n 
1 104 TYR n 
1 105 VAL n 
1 106 ILE n 
1 107 VAL n 
1 108 ARG n 
1 109 TYR n 
1 110 THR n 
1 111 LYS n 
1 112 MET n 
1 113 LYS n 
1 114 THR n 
1 115 ALA n 
1 116 THR n 
1 117 ASN n 
1 118 ILE n 
1 119 TYR n 
1 120 ILE n 
1 121 PHE n 
1 122 ASN n 
1 123 LEU n 
1 124 ALA n 
1 125 LEU n 
1 126 ALA n 
1 127 ASP n 
1 128 ALA n 
1 129 LEU n 
1 130 ALA n 
1 131 THR n 
1 132 SER n 
1 133 THR n 
1 134 LEU n 
1 135 PRO n 
1 136 PHE n 
1 137 GLN n 
1 138 SER n 
1 139 VAL n 
1 140 ASN n 
1 141 TYR n 
1 142 LEU n 
1 143 MET n 
1 144 GLY n 
1 145 THR n 
1 146 TRP n 
1 147 PRO n 
1 148 PHE n 
1 149 GLY n 
1 150 THR n 
1 151 ILE n 
1 152 LEU n 
1 153 CYS n 
1 154 LYS n 
1 155 ILE n 
1 156 VAL n 
1 157 ILE n 
1 158 SER n 
1 159 ILE n 
1 160 ASP n 
1 161 TYR n 
1 162 TYR n 
1 163 ASN n 
1 164 MET n 
1 165 PHE n 
1 166 THR n 
1 167 SER n 
1 168 ILE n 
1 169 PHE n 
1 170 THR n 
1 171 LEU n 
1 172 CYS n 
1 173 THR n 
1 174 MET n 
1 175 SER n 
1 176 VAL n 
1 177 ASP n 
1 178 ARG n 
1 179 TYR n 
1 180 ILE n 
1 181 ALA n 
1 182 VAL n 
1 183 CYS n 
1 184 HIS n 
1 185 PRO n 
1 186 VAL n 
1 187 LYS n 
1 188 ALA n 
1 189 LEU n 
1 190 ASP n 
1 191 PHE n 
1 192 ARG n 
1 193 THR n 
1 194 PRO n 
1 195 ARG n 
1 196 ASN n 
1 197 ALA n 
1 198 LYS n 
1 199 ILE n 
1 200 ILE n 
1 201 ASN n 
1 202 VAL n 
1 203 CYS n 
1 204 ASN n 
1 205 TRP n 
1 206 ILE n 
1 207 LEU n 
1 208 SER n 
1 209 SER n 
1 210 ALA n 
1 211 ILE n 
1 212 GLY n 
1 213 LEU n 
1 214 PRO n 
1 215 VAL n 
1 216 MET n 
1 217 PHE n 
1 218 MET n 
1 219 ALA n 
1 220 THR n 
1 221 THR n 
1 222 LYS n 
1 223 TYR n 
1 224 ARG n 
1 225 GLN n 
1 226 GLY n 
1 227 SER n 
1 228 ILE n 
1 229 ASP n 
1 230 CYS n 
1 231 THR n 
1 232 LEU n 
1 233 THR n 
1 234 PHE n 
1 235 SER n 
1 236 HIS n 
1 237 PRO n 
1 238 THR n 
1 239 TRP n 
1 240 TYR n 
1 241 TRP n 
1 242 GLU n 
1 243 ASN n 
1 244 LEU n 
1 245 LEU n 
1 246 LYS n 
1 247 ILE n 
1 248 CYS n 
1 249 VAL n 
1 250 PHE n 
1 251 ILE n 
1 252 PHE n 
1 253 ALA n 
1 254 PHE n 
1 255 ILE n 
1 256 MET n 
1 257 PRO n 
1 258 VAL n 
1 259 LEU n 
1 260 ILE n 
1 261 ILE n 
1 262 THR n 
1 263 VAL n 
1 264 CYS n 
1 265 TYR n 
1 266 GLY n 
1 267 LEU n 
1 268 MET n 
1 269 ILE n 
1 270 LEU n 
1 271 ARG n 
1 272 LEU n 
1 273 LYS n 
1 274 SER n 
1 275 VAL n 
1 276 ARG n 
1 277 LEU n 
1 278 LEU n 
1 279 SER n 
1 280 GLY n 
1 281 SER n 
1 282 ARG n 
1 283 GLU n 
1 284 LYS n 
1 285 ASP n 
1 286 ARG n 
1 287 ASN n 
1 288 LEU n 
1 289 ARG n 
1 290 ARG n 
1 291 ILE n 
1 292 THR n 
1 293 ARG n 
1 294 MET n 
1 295 VAL n 
1 296 LEU n 
1 297 VAL n 
1 298 VAL n 
1 299 VAL n 
1 300 ALA n 
1 301 VAL n 
1 302 PHE n 
1 303 ILE n 
1 304 VAL n 
1 305 CYS n 
1 306 TRP n 
1 307 THR n 
1 308 PRO n 
1 309 ILE n 
1 310 HIS n 
1 311 ILE n 
1 312 TYR n 
1 313 VAL n 
1 314 ILE n 
1 315 ILE n 
1 316 LYS n 
1 317 ALA n 
1 318 LEU n 
1 319 VAL n 
1 320 THR n 
1 321 ILE n 
1 322 PRO n 
1 323 GLU n 
1 324 THR n 
1 325 THR n 
1 326 PHE n 
1 327 GLN n 
1 328 THR n 
1 329 VAL n 
1 330 SER n 
1 331 TRP n 
1 332 HIS n 
1 333 PHE n 
1 334 CYS n 
1 335 ILE n 
1 336 ALA n 
1 337 LEU n 
1 338 GLY n 
1 339 TYR n 
1 340 THR n 
1 341 ASN n 
1 342 SER n 
1 343 CYS n 
1 344 LEU n 
1 345 ASN n 
1 346 PRO n 
1 347 VAL n 
1 348 LEU n 
1 349 TYR n 
1 350 ALA n 
1 351 PHE n 
1 352 LEU n 
1 353 ASP n 
1 354 GLU n 
1 355 ASN n 
1 356 PHE n 
1 357 LYS n 
1 358 ARG n 
1 359 CYS n 
1 360 PHE n 
1 361 ARG n 
1 362 GLU n 
1 363 PHE n 
1 364 CYS n 
1 365 ILE n 
1 366 PRO n 
1 367 THR n 
1 368 SER n 
1 369 SER n 
1 370 ASN n 
1 371 ILE n 
1 372 GLU n 
1 373 GLN n 
1 374 GLN n 
1 375 ASN n 
1 376 SER n 
1 377 THR n 
1 378 ARG n 
1 379 ILE n 
1 380 ARG n 
1 381 GLN n 
1 382 ASN n 
1 383 THR n 
1 384 ARG n 
1 385 ASP n 
1 386 HIS n 
1 387 PRO n 
1 388 SER n 
1 389 THR n 
1 390 ALA n 
1 391 ASN n 
1 392 THR n 
1 393 VAL n 
1 394 ASP n 
1 395 ARG n 
1 396 THR n 
1 397 ASN n 
1 398 HIS n 
1 399 GLN n 
1 400 LEU n 
1 401 GLU n 
1 402 ASN n 
1 403 LEU n 
1 404 GLU n 
1 405 ALA n 
1 406 GLU n 
1 407 THR n 
1 408 ALA n 
1 409 PRO n 
1 410 LEU n 
1 411 PRO n 
2 1   GLN n 
2 2   ARG n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  GLN n 
2 14  PRO n 
2 15  GLY n 
2 16  GLY n 
2 17  SER n 
2 18  LEU n 
2 19  ARG n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ALA n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  THR n 
2 28  ILE n 
2 29  PHE n 
2 30  ARG n 
2 31  LEU n 
2 32  TYR n 
2 33  ASP n 
2 34  MET n 
2 35  GLY n 
2 36  TRP n 
2 37  PHE n 
2 38  ARG n 
2 39  GLN n 
2 40  ALA n 
2 41  PRO n 
2 42  GLY n 
2 43  LYS n 
2 44  GLU n 
2 45  ARG n 
2 46  GLU n 
2 47  GLY n 
2 48  VAL n 
2 49  ALA n 
2 50  SER n 
2 51  ILE n 
2 52  THR n 
2 53  SER n 
2 54  GLY n 
2 55  GLY n 
2 56  SER n 
2 57  THR n 
2 58  LYS n 
2 59  TYR n 
2 60  ALA n 
2 61  ASP n 
2 62  SER n 
2 63  VAL n 
2 64  LYS n 
2 65  GLY n 
2 66  ARG n 
2 67  PHE n 
2 68  THR n 
2 69  ILE n 
2 70  SER n 
2 71  ARG n 
2 72  ASP n 
2 73  ASN n 
2 74  ALA n 
2 75  LYS n 
2 76  ASN n 
2 77  THR n 
2 78  VAL n 
2 79  TYR n 
2 80  LEU n 
2 81  GLN n 
2 82  MET n 
2 83  ASN n 
2 84  SER n 
2 85  LEU n 
2 86  GLU n 
2 87  PRO n 
2 88  GLU n 
2 89  ASP n 
2 90  THR n 
2 91  ALA n 
2 92  VAL n 
2 93  TYR n 
2 94  TYR n 
2 95  CYS n 
2 96  ASN n 
2 97  ALA n 
2 98  GLU n 
2 99  TYR n 
2 100 ARG n 
2 101 THR n 
2 102 GLY n 
2 103 ILE n 
2 104 TRP n 
2 105 GLU n 
2 106 GLU n 
2 107 LEU n 
2 108 LEU n 
2 109 ASP n 
2 110 GLY n 
2 111 TRP n 
2 112 GLY n 
2 113 LYS n 
2 114 GLY n 
2 115 THR n 
2 116 PRO n 
2 117 VAL n 
2 118 THR n 
2 119 VAL n 
2 120 SER n 
2 121 SER n 
2 122 HIS n 
2 123 HIS n 
2 124 HIS n 
2 125 HIS n 
2 126 HIS n 
2 127 HIS n 
2 128 GLU n 
2 129 PRO n 
2 130 GLU n 
2 131 ALA n 
3 1   GLU n 
3 2   ILE n 
3 3   SER n 
3 4   GLU n 
3 5   VAL n 
3 6   GLN n 
3 7   LEU n 
3 8   VAL n 
3 9   GLU n 
3 10  SER n 
3 11  GLY n 
3 12  GLY n 
3 13  GLY n 
3 14  LEU n 
3 15  VAL n 
3 16  GLN n 
3 17  PRO n 
3 18  GLY n 
3 19  GLY n 
3 20  SER n 
3 21  LEU n 
3 22  ARG n 
3 23  LEU n 
3 24  SER n 
3 25  CYS n 
3 26  ALA n 
3 27  ALA n 
3 28  SER n 
3 29  GLY n 
3 30  PHE n 
3 31  ASN n 
3 32  PHE n 
3 33  SER n 
3 34  TYR n 
3 35  TYR n 
3 36  SER n 
3 37  ILE n 
3 38  HIS n 
3 39  TRP n 
3 40  VAL n 
3 41  ARG n 
3 42  GLN n 
3 43  ALA n 
3 44  PRO n 
3 45  GLY n 
3 46  LYS n 
3 47  GLY n 
3 48  LEU n 
3 49  GLU n 
3 50  TRP n 
3 51  VAL n 
3 52  ALA n 
3 53  TYR n 
3 54  ILE n 
3 55  SER n 
3 56  SER n 
3 57  SER n 
3 58  SER n 
3 59  SER n 
3 60  TYR n 
3 61  THR n 
3 62  SER n 
3 63  TYR n 
3 64  ALA n 
3 65  ASP n 
3 66  SER n 
3 67  VAL n 
3 68  LYS n 
3 69  GLY n 
3 70  ARG n 
3 71  PHE n 
3 72  THR n 
3 73  ILE n 
3 74  SER n 
3 75  ALA n 
3 76  ASP n 
3 77  THR n 
3 78  SER n 
3 79  LYS n 
3 80  ASN n 
3 81  THR n 
3 82  ALA n 
3 83  TYR n 
3 84  LEU n 
3 85  GLN n 
3 86  MET n 
3 87  ASN n 
3 88  SER n 
3 89  LEU n 
3 90  ARG n 
3 91  ALA n 
3 92  GLU n 
3 93  ASP n 
3 94  THR n 
3 95  ALA n 
3 96  VAL n 
3 97  TYR n 
3 98  TYR n 
3 99  CYS n 
3 100 ALA n 
3 101 ARG n 
3 102 GLY n 
3 103 TYR n 
3 104 GLN n 
3 105 TYR n 
3 106 TRP n 
3 107 GLN n 
3 108 TYR n 
3 109 HIS n 
3 110 ALA n 
3 111 SER n 
3 112 TRP n 
3 113 TYR n 
3 114 TRP n 
3 115 ASN n 
3 116 GLY n 
3 117 GLY n 
3 118 LEU n 
3 119 ASP n 
3 120 TYR n 
3 121 TRP n 
3 122 GLY n 
3 123 GLN n 
3 124 GLY n 
3 125 THR n 
3 126 LEU n 
3 127 VAL n 
3 128 THR n 
3 129 VAL n 
3 130 SER n 
3 131 SER n 
3 132 ALA n 
3 133 SER n 
3 134 THR n 
3 135 LYS n 
3 136 GLY n 
3 137 PRO n 
3 138 SER n 
3 139 VAL n 
3 140 PHE n 
3 141 PRO n 
3 142 LEU n 
3 143 ALA n 
3 144 PRO n 
3 145 SER n 
3 146 SER n 
3 147 LYS n 
3 148 SER n 
3 149 THR n 
3 150 SER n 
3 151 GLY n 
3 152 GLY n 
3 153 THR n 
3 154 ALA n 
3 155 ALA n 
3 156 LEU n 
3 157 GLY n 
3 158 CYS n 
3 159 LEU n 
3 160 VAL n 
3 161 LYS n 
3 162 ASP n 
3 163 TYR n 
3 164 PHE n 
3 165 PRO n 
3 166 GLU n 
3 167 PRO n 
3 168 VAL n 
3 169 THR n 
3 170 VAL n 
3 171 SER n 
3 172 TRP n 
3 173 ASN n 
3 174 SER n 
3 175 GLY n 
3 176 ALA n 
3 177 LEU n 
3 178 THR n 
3 179 SER n 
3 180 GLY n 
3 181 VAL n 
3 182 HIS n 
3 183 THR n 
3 184 PHE n 
3 185 PRO n 
3 186 ALA n 
3 187 VAL n 
3 188 LEU n 
3 189 GLN n 
3 190 SER n 
3 191 SER n 
3 192 GLY n 
3 193 LEU n 
3 194 TYR n 
3 195 SER n 
3 196 LEU n 
3 197 SER n 
3 198 SER n 
3 199 VAL n 
3 200 VAL n 
3 201 THR n 
3 202 VAL n 
3 203 PRO n 
3 204 SER n 
3 205 SER n 
3 206 SER n 
3 207 LEU n 
3 208 GLY n 
3 209 THR n 
3 210 GLN n 
3 211 THR n 
3 212 TYR n 
3 213 ILE n 
3 214 CYS n 
3 215 ASN n 
3 216 VAL n 
3 217 ASN n 
3 218 HIS n 
3 219 LYS n 
3 220 PRO n 
3 221 SER n 
3 222 ASN n 
3 223 THR n 
3 224 LYS n 
3 225 VAL n 
3 226 ASP n 
3 227 LYS n 
3 228 LYS n 
3 229 VAL n 
3 230 GLU n 
3 231 PRO n 
3 232 LYS n 
3 233 SER n 
3 234 CYS n 
3 235 ASP n 
3 236 LYS n 
3 237 THR n 
3 238 HIS n 
3 239 THR n 
4 1   SER n 
4 2   ASP n 
4 3   ILE n 
4 4   GLN n 
4 5   MET n 
4 6   THR n 
4 7   GLN n 
4 8   SER n 
4 9   PRO n 
4 10  SER n 
4 11  SER n 
4 12  LEU n 
4 13  SER n 
4 14  ALA n 
4 15  SER n 
4 16  VAL n 
4 17  GLY n 
4 18  ASP n 
4 19  ARG n 
4 20  VAL n 
4 21  THR n 
4 22  ILE n 
4 23  THR n 
4 24  CYS n 
4 25  ARG n 
4 26  ALA n 
4 27  SER n 
4 28  GLN n 
4 29  SER n 
4 30  VAL n 
4 31  SER n 
4 32  SER n 
4 33  ALA n 
4 34  VAL n 
4 35  ALA n 
4 36  TRP n 
4 37  TYR n 
4 38  GLN n 
4 39  GLN n 
4 40  LYS n 
4 41  PRO n 
4 42  GLY n 
4 43  LYS n 
4 44  ALA n 
4 45  PRO n 
4 46  LYS n 
4 47  LEU n 
4 48  LEU n 
4 49  ILE n 
4 50  TYR n 
4 51  SER n 
4 52  ALA n 
4 53  SER n 
4 54  SER n 
4 55  LEU n 
4 56  TYR n 
4 57  SER n 
4 58  GLY n 
4 59  VAL n 
4 60  PRO n 
4 61  SER n 
4 62  ARG n 
4 63  PHE n 
4 64  SER n 
4 65  GLY n 
4 66  SER n 
4 67  ARG n 
4 68  SER n 
4 69  GLY n 
4 70  THR n 
4 71  ASP n 
4 72  PHE n 
4 73  THR n 
4 74  LEU n 
4 75  THR n 
4 76  ILE n 
4 77  SER n 
4 78  SER n 
4 79  LEU n 
4 80  GLN n 
4 81  PRO n 
4 82  GLU n 
4 83  ASP n 
4 84  PHE n 
4 85  ALA n 
4 86  THR n 
4 87  TYR n 
4 88  TYR n 
4 89  CYS n 
4 90  GLN n 
4 91  GLN n 
4 92  SER n 
4 93  SER n 
4 94  SER n 
4 95  SER n 
4 96  LEU n 
4 97  ILE n 
4 98  THR n 
4 99  PHE n 
4 100 GLY n 
4 101 GLN n 
4 102 GLY n 
4 103 THR n 
4 104 LYS n 
4 105 VAL n 
4 106 GLU n 
4 107 ILE n 
4 108 LYS n 
4 109 ARG n 
4 110 THR n 
4 111 VAL n 
4 112 ALA n 
4 113 ALA n 
4 114 PRO n 
4 115 SER n 
4 116 VAL n 
4 117 PHE n 
4 118 ILE n 
4 119 PHE n 
4 120 PRO n 
4 121 PRO n 
4 122 SER n 
4 123 ASP n 
4 124 SER n 
4 125 GLN n 
4 126 LEU n 
4 127 LYS n 
4 128 SER n 
4 129 GLY n 
4 130 THR n 
4 131 ALA n 
4 132 SER n 
4 133 VAL n 
4 134 VAL n 
4 135 CYS n 
4 136 LEU n 
4 137 LEU n 
4 138 ASN n 
4 139 ASN n 
4 140 PHE n 
4 141 TYR n 
4 142 PRO n 
4 143 ARG n 
4 144 GLU n 
4 145 ALA n 
4 146 LYS n 
4 147 VAL n 
4 148 GLN n 
4 149 TRP n 
4 150 LYS n 
4 151 VAL n 
4 152 ASP n 
4 153 ASN n 
4 154 ALA n 
4 155 LEU n 
4 156 GLN n 
4 157 SER n 
4 158 GLY n 
4 159 ASN n 
4 160 SER n 
4 161 GLN n 
4 162 GLU n 
4 163 SER n 
4 164 VAL n 
4 165 THR n 
4 166 GLU n 
4 167 GLN n 
4 168 ASP n 
4 169 SER n 
4 170 LYS n 
4 171 ASP n 
4 172 SER n 
4 173 THR n 
4 174 TYR n 
4 175 SER n 
4 176 LEU n 
4 177 SER n 
4 178 SER n 
4 179 THR n 
4 180 LEU n 
4 181 THR n 
4 182 LEU n 
4 183 SER n 
4 184 LYS n 
4 185 ALA n 
4 186 ASP n 
4 187 TYR n 
4 188 GLU n 
4 189 LYS n 
4 190 HIS n 
4 191 LYS n 
4 192 VAL n 
4 193 TYR n 
4 194 ALA n 
4 195 CYS n 
4 196 GLU n 
4 197 VAL n 
4 198 THR n 
4 199 HIS n 
4 200 GLN n 
4 201 GLY n 
4 202 LEU n 
4 203 SER n 
4 204 SER n 
4 205 PRO n 
4 206 VAL n 
4 207 THR n 
4 208 LYS n 
4 209 SER n 
4 210 PHE n 
4 211 ASN n 
4 212 ARG n 
4 213 GLY n 
4 214 GLU n 
4 215 CYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 411 human ? 'OPRM1, MOR1' ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? human 
'Homo sapiens'     9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 131 ?     ? ?             ? ? ? ? ? ? 'synthetic construct' 32630 ? ? ? ? ? ? ? ?     
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 239 ?     ? ?             ? ? ? ? ? ? 'synthetic construct' 32630 ? ? ? ? ? ? ? ?     
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 215 ?     ? ?             ? ? ? ? ? ? 'synthetic construct' 32630 ? ? ? ? ? ? ? ?     
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1BNM non-polymer         . 
;methyl (1S,3R,4S,6S,8M)-2-[(1-ethyl-1H-pyrazol-4-yl)methyl]-8-(3-hydroxyphenyl)-3,4-dimethyl-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylate
;
? 'C23 H29 N3 O3'  395.495 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   -10 ?   ?   ?   A . n 
A 1 2   TYR 2   -9  ?   ?   ?   A . n 
A 1 3   LYS 3   -8  ?   ?   ?   A . n 
A 1 4   ASP 4   -7  ?   ?   ?   A . n 
A 1 5   ASP 5   -6  ?   ?   ?   A . n 
A 1 6   ASP 6   -5  ?   ?   ?   A . n 
A 1 7   ASP 7   -4  ?   ?   ?   A . n 
A 1 8   ALA 8   -3  ?   ?   ?   A . n 
A 1 9   SER 9   -2  ?   ?   ?   A . n 
A 1 10  ILE 10  -1  ?   ?   ?   A . n 
A 1 11  ASP 11  0   ?   ?   ?   A . n 
A 1 12  MET 12  1   ?   ?   ?   A . n 
A 1 13  ASP 13  2   ?   ?   ?   A . n 
A 1 14  SER 14  3   ?   ?   ?   A . n 
A 1 15  SER 15  4   ?   ?   ?   A . n 
A 1 16  ALA 16  5   ?   ?   ?   A . n 
A 1 17  ALA 17  6   ?   ?   ?   A . n 
A 1 18  PRO 18  7   ?   ?   ?   A . n 
A 1 19  THR 19  8   ?   ?   ?   A . n 
A 1 20  ASN 20  9   ?   ?   ?   A . n 
A 1 21  ALA 21  10  ?   ?   ?   A . n 
A 1 22  SER 22  11  ?   ?   ?   A . n 
A 1 23  ASN 23  12  ?   ?   ?   A . n 
A 1 24  CYS 24  13  ?   ?   ?   A . n 
A 1 25  THR 25  14  ?   ?   ?   A . n 
A 1 26  ASP 26  15  ?   ?   ?   A . n 
A 1 27  ALA 27  16  ?   ?   ?   A . n 
A 1 28  LEU 28  17  ?   ?   ?   A . n 
A 1 29  ALA 29  18  ?   ?   ?   A . n 
A 1 30  TYR 30  19  ?   ?   ?   A . n 
A 1 31  SER 31  20  ?   ?   ?   A . n 
A 1 32  SER 32  21  ?   ?   ?   A . n 
A 1 33  CYS 33  22  ?   ?   ?   A . n 
A 1 34  SER 34  23  ?   ?   ?   A . n 
A 1 35  PRO 35  24  ?   ?   ?   A . n 
A 1 36  ALA 36  25  ?   ?   ?   A . n 
A 1 37  PRO 37  26  ?   ?   ?   A . n 
A 1 38  SER 38  27  ?   ?   ?   A . n 
A 1 39  PRO 39  28  ?   ?   ?   A . n 
A 1 40  GLY 40  29  ?   ?   ?   A . n 
A 1 41  SER 41  30  ?   ?   ?   A . n 
A 1 42  TRP 42  31  ?   ?   ?   A . n 
A 1 43  VAL 43  32  ?   ?   ?   A . n 
A 1 44  ASN 44  33  ?   ?   ?   A . n 
A 1 45  LEU 45  34  ?   ?   ?   A . n 
A 1 46  SER 46  35  ?   ?   ?   A . n 
A 1 47  HIS 47  36  ?   ?   ?   A . n 
A 1 48  LEU 48  37  ?   ?   ?   A . n 
A 1 49  ASP 49  38  ?   ?   ?   A . n 
A 1 50  GLY 50  39  ?   ?   ?   A . n 
A 1 51  ASN 51  40  ?   ?   ?   A . n 
A 1 52  LEU 52  41  ?   ?   ?   A . n 
A 1 53  SER 53  42  ?   ?   ?   A . n 
A 1 54  ASP 54  43  ?   ?   ?   A . n 
A 1 55  PRO 55  44  ?   ?   ?   A . n 
A 1 56  CYS 56  45  ?   ?   ?   A . n 
A 1 57  GLY 57  46  ?   ?   ?   A . n 
A 1 58  PRO 58  47  ?   ?   ?   A . n 
A 1 59  ASN 59  48  ?   ?   ?   A . n 
A 1 60  ARG 60  49  ?   ?   ?   A . n 
A 1 61  THR 61  50  ?   ?   ?   A . n 
A 1 62  ASP 62  51  ?   ?   ?   A . n 
A 1 63  LEU 63  52  ?   ?   ?   A . n 
A 1 64  GLY 64  53  ?   ?   ?   A . n 
A 1 65  GLY 65  54  ?   ?   ?   A . n 
A 1 66  ARG 66  55  ?   ?   ?   A . n 
A 1 67  ASP 67  56  ?   ?   ?   A . n 
A 1 68  SER 68  57  ?   ?   ?   A . n 
A 1 69  LEU 69  58  ?   ?   ?   A . n 
A 1 70  CYS 70  59  ?   ?   ?   A . n 
A 1 71  PRO 71  60  ?   ?   ?   A . n 
A 1 72  PRO 72  61  ?   ?   ?   A . n 
A 1 73  THR 73  62  ?   ?   ?   A . n 
A 1 74  GLY 74  63  ?   ?   ?   A . n 
A 1 75  SER 75  64  ?   ?   ?   A . n 
A 1 76  PRO 76  65  ?   ?   ?   A . n 
A 1 77  SER 77  66  ?   ?   ?   A . n 
A 1 78  MET 78  67  67  MET MET A . n 
A 1 79  ILE 79  68  68  ILE ILE A . n 
A 1 80  THR 80  69  69  THR THR A . n 
A 1 81  ALA 81  70  70  ALA ALA A . n 
A 1 82  ILE 82  71  71  ILE ILE A . n 
A 1 83  THR 83  72  72  THR THR A . n 
A 1 84  ILE 84  73  73  ILE ILE A . n 
A 1 85  MET 85  74  74  MET MET A . n 
A 1 86  ALA 86  75  75  ALA ALA A . n 
A 1 87  LEU 87  76  76  LEU LEU A . n 
A 1 88  TYR 88  77  77  TYR TYR A . n 
A 1 89  SER 89  78  78  SER SER A . n 
A 1 90  ILE 90  79  79  ILE ILE A . n 
A 1 91  VAL 91  80  80  VAL VAL A . n 
A 1 92  CYS 92  81  81  CYS CYS A . n 
A 1 93  VAL 93  82  82  VAL VAL A . n 
A 1 94  VAL 94  83  83  VAL VAL A . n 
A 1 95  GLY 95  84  84  GLY GLY A . n 
A 1 96  LEU 96  85  85  LEU LEU A . n 
A 1 97  PHE 97  86  86  PHE PHE A . n 
A 1 98  GLY 98  87  87  GLY GLY A . n 
A 1 99  ASN 99  88  88  ASN ASN A . n 
A 1 100 PHE 100 89  89  PHE PHE A . n 
A 1 101 LEU 101 90  90  LEU LEU A . n 
A 1 102 VAL 102 91  91  VAL VAL A . n 
A 1 103 MET 103 92  92  MET MET A . n 
A 1 104 TYR 104 93  93  TYR TYR A . n 
A 1 105 VAL 105 94  94  VAL VAL A . n 
A 1 106 ILE 106 95  95  ILE ILE A . n 
A 1 107 VAL 107 96  96  VAL VAL A . n 
A 1 108 ARG 108 97  97  ARG ARG A . n 
A 1 109 TYR 109 98  98  TYR TYR A . n 
A 1 110 THR 110 99  99  THR THR A . n 
A 1 111 LYS 111 100 100 LYS LYS A . n 
A 1 112 MET 112 101 101 MET MET A . n 
A 1 113 LYS 113 102 102 LYS LYS A . n 
A 1 114 THR 114 103 103 THR THR A . n 
A 1 115 ALA 115 104 104 ALA ALA A . n 
A 1 116 THR 116 105 105 THR THR A . n 
A 1 117 ASN 117 106 106 ASN ASN A . n 
A 1 118 ILE 118 107 107 ILE ILE A . n 
A 1 119 TYR 119 108 108 TYR TYR A . n 
A 1 120 ILE 120 109 109 ILE ILE A . n 
A 1 121 PHE 121 110 110 PHE PHE A . n 
A 1 122 ASN 122 111 111 ASN ASN A . n 
A 1 123 LEU 123 112 112 LEU LEU A . n 
A 1 124 ALA 124 113 113 ALA ALA A . n 
A 1 125 LEU 125 114 114 LEU LEU A . n 
A 1 126 ALA 126 115 115 ALA ALA A . n 
A 1 127 ASP 127 116 116 ASP ASP A . n 
A 1 128 ALA 128 117 117 ALA ALA A . n 
A 1 129 LEU 129 118 118 LEU LEU A . n 
A 1 130 ALA 130 119 119 ALA ALA A . n 
A 1 131 THR 131 120 120 THR THR A . n 
A 1 132 SER 132 121 121 SER SER A . n 
A 1 133 THR 133 122 122 THR THR A . n 
A 1 134 LEU 134 123 123 LEU LEU A . n 
A 1 135 PRO 135 124 124 PRO PRO A . n 
A 1 136 PHE 136 125 125 PHE PHE A . n 
A 1 137 GLN 137 126 126 GLN GLN A . n 
A 1 138 SER 138 127 127 SER SER A . n 
A 1 139 VAL 139 128 128 VAL VAL A . n 
A 1 140 ASN 140 129 129 ASN ASN A . n 
A 1 141 TYR 141 130 130 TYR TYR A . n 
A 1 142 LEU 142 131 131 LEU LEU A . n 
A 1 143 MET 143 132 132 MET MET A . n 
A 1 144 GLY 144 133 133 GLY GLY A . n 
A 1 145 THR 145 134 134 THR THR A . n 
A 1 146 TRP 146 135 135 TRP TRP A . n 
A 1 147 PRO 147 136 136 PRO PRO A . n 
A 1 148 PHE 148 137 137 PHE PHE A . n 
A 1 149 GLY 149 138 138 GLY GLY A . n 
A 1 150 THR 150 139 139 THR THR A . n 
A 1 151 ILE 151 140 140 ILE ILE A . n 
A 1 152 LEU 152 141 141 LEU LEU A . n 
A 1 153 CYS 153 142 142 CYS CYS A . n 
A 1 154 LYS 154 143 143 LYS LYS A . n 
A 1 155 ILE 155 144 144 ILE ILE A . n 
A 1 156 VAL 156 145 145 VAL VAL A . n 
A 1 157 ILE 157 146 146 ILE ILE A . n 
A 1 158 SER 158 147 147 SER SER A . n 
A 1 159 ILE 159 148 148 ILE ILE A . n 
A 1 160 ASP 160 149 149 ASP ASP A . n 
A 1 161 TYR 161 150 150 TYR TYR A . n 
A 1 162 TYR 162 151 151 TYR TYR A . n 
A 1 163 ASN 163 152 152 ASN ASN A . n 
A 1 164 MET 164 153 153 MET MET A . n 
A 1 165 PHE 165 154 154 PHE PHE A . n 
A 1 166 THR 166 155 155 THR THR A . n 
A 1 167 SER 167 156 156 SER SER A . n 
A 1 168 ILE 168 157 157 ILE ILE A . n 
A 1 169 PHE 169 158 158 PHE PHE A . n 
A 1 170 THR 170 159 159 THR THR A . n 
A 1 171 LEU 171 160 160 LEU LEU A . n 
A 1 172 CYS 172 161 161 CYS CYS A . n 
A 1 173 THR 173 162 162 THR THR A . n 
A 1 174 MET 174 163 163 MET MET A . n 
A 1 175 SER 175 164 164 SER SER A . n 
A 1 176 VAL 176 165 165 VAL VAL A . n 
A 1 177 ASP 177 166 166 ASP ASP A . n 
A 1 178 ARG 178 167 167 ARG ARG A . n 
A 1 179 TYR 179 168 168 TYR TYR A . n 
A 1 180 ILE 180 169 169 ILE ILE A . n 
A 1 181 ALA 181 170 170 ALA ALA A . n 
A 1 182 VAL 182 171 171 VAL VAL A . n 
A 1 183 CYS 183 172 172 CYS CYS A . n 
A 1 184 HIS 184 173 173 HIS HIS A . n 
A 1 185 PRO 185 174 174 PRO PRO A . n 
A 1 186 VAL 186 175 175 VAL VAL A . n 
A 1 187 LYS 187 176 176 LYS LYS A . n 
A 1 188 ALA 188 177 177 ALA ALA A . n 
A 1 189 LEU 189 178 178 LEU LEU A . n 
A 1 190 ASP 190 179 179 ASP ASP A . n 
A 1 191 PHE 191 180 180 PHE PHE A . n 
A 1 192 ARG 192 181 181 ARG ARG A . n 
A 1 193 THR 193 182 182 THR THR A . n 
A 1 194 PRO 194 183 183 PRO PRO A . n 
A 1 195 ARG 195 184 184 ARG ARG A . n 
A 1 196 ASN 196 185 185 ASN ASN A . n 
A 1 197 ALA 197 186 186 ALA ALA A . n 
A 1 198 LYS 198 187 187 LYS LYS A . n 
A 1 199 ILE 199 188 188 ILE ILE A . n 
A 1 200 ILE 200 189 189 ILE ILE A . n 
A 1 201 ASN 201 190 190 ASN ASN A . n 
A 1 202 VAL 202 191 191 VAL VAL A . n 
A 1 203 CYS 203 192 192 CYS CYS A . n 
A 1 204 ASN 204 193 193 ASN ASN A . n 
A 1 205 TRP 205 194 194 TRP TRP A . n 
A 1 206 ILE 206 195 195 ILE ILE A . n 
A 1 207 LEU 207 196 196 LEU LEU A . n 
A 1 208 SER 208 197 197 SER SER A . n 
A 1 209 SER 209 198 198 SER SER A . n 
A 1 210 ALA 210 199 199 ALA ALA A . n 
A 1 211 ILE 211 200 200 ILE ILE A . n 
A 1 212 GLY 212 201 201 GLY GLY A . n 
A 1 213 LEU 213 202 202 LEU LEU A . n 
A 1 214 PRO 214 203 203 PRO PRO A . n 
A 1 215 VAL 215 204 204 VAL VAL A . n 
A 1 216 MET 216 205 205 MET MET A . n 
A 1 217 PHE 217 206 206 PHE PHE A . n 
A 1 218 MET 218 207 207 MET MET A . n 
A 1 219 ALA 219 208 208 ALA ALA A . n 
A 1 220 THR 220 209 209 THR THR A . n 
A 1 221 THR 221 210 210 THR THR A . n 
A 1 222 LYS 222 211 211 LYS LYS A . n 
A 1 223 TYR 223 212 212 TYR TYR A . n 
A 1 224 ARG 224 213 213 ARG ARG A . n 
A 1 225 GLN 225 214 214 GLN GLN A . n 
A 1 226 GLY 226 215 215 GLY GLY A . n 
A 1 227 SER 227 216 216 SER SER A . n 
A 1 228 ILE 228 217 217 ILE ILE A . n 
A 1 229 ASP 229 218 218 ASP ASP A . n 
A 1 230 CYS 230 219 219 CYS CYS A . n 
A 1 231 THR 231 220 220 THR THR A . n 
A 1 232 LEU 232 221 221 LEU LEU A . n 
A 1 233 THR 233 222 222 THR THR A . n 
A 1 234 PHE 234 223 223 PHE PHE A . n 
A 1 235 SER 235 224 224 SER SER A . n 
A 1 236 HIS 236 225 ?   ?   ?   A . n 
A 1 237 PRO 237 226 ?   ?   ?   A . n 
A 1 238 THR 238 227 227 THR THR A . n 
A 1 239 TRP 239 228 228 TRP TRP A . n 
A 1 240 TYR 240 229 229 TYR TYR A . n 
A 1 241 TRP 241 230 230 TRP TRP A . n 
A 1 242 GLU 242 231 231 GLU GLU A . n 
A 1 243 ASN 243 232 232 ASN ASN A . n 
A 1 244 LEU 244 233 233 LEU LEU A . n 
A 1 245 LEU 245 234 234 LEU LEU A . n 
A 1 246 LYS 246 235 235 LYS LYS A . n 
A 1 247 ILE 247 236 236 ILE ILE A . n 
A 1 248 CYS 248 237 237 CYS CYS A . n 
A 1 249 VAL 249 238 238 VAL VAL A . n 
A 1 250 PHE 250 239 239 PHE PHE A . n 
A 1 251 ILE 251 240 240 ILE ILE A . n 
A 1 252 PHE 252 241 241 PHE PHE A . n 
A 1 253 ALA 253 242 242 ALA ALA A . n 
A 1 254 PHE 254 243 243 PHE PHE A . n 
A 1 255 ILE 255 244 244 ILE ILE A . n 
A 1 256 MET 256 245 245 MET MET A . n 
A 1 257 PRO 257 246 246 PRO PRO A . n 
A 1 258 VAL 258 247 247 VAL VAL A . n 
A 1 259 LEU 259 248 248 LEU LEU A . n 
A 1 260 ILE 260 249 249 ILE ILE A . n 
A 1 261 ILE 261 250 250 ILE ILE A . n 
A 1 262 THR 262 251 251 THR THR A . n 
A 1 263 VAL 263 252 252 VAL VAL A . n 
A 1 264 CYS 264 253 253 CYS CYS A . n 
A 1 265 TYR 265 254 254 TYR TYR A . n 
A 1 266 GLY 266 255 255 GLY GLY A . n 
A 1 267 LEU 267 256 256 LEU LEU A . n 
A 1 268 MET 268 257 257 MET MET A . n 
A 1 269 ILE 269 258 258 ILE ILE A . n 
A 1 270 LEU 270 259 259 LEU LEU A . n 
A 1 271 ARG 271 260 260 ARG ARG A . n 
A 1 272 LEU 272 261 261 LEU LEU A . n 
A 1 273 LYS 273 262 262 LYS LYS A . n 
A 1 274 SER 274 263 263 SER SER A . n 
A 1 275 VAL 275 264 264 VAL VAL A . n 
A 1 276 ARG 276 265 265 ARG ARG A . n 
A 1 277 LEU 277 266 266 LEU LEU A . n 
A 1 278 LEU 278 267 267 LEU LEU A . n 
A 1 279 SER 279 268 268 SER SER A . n 
A 1 280 GLY 280 269 269 GLY GLY A . n 
A 1 281 SER 281 270 270 SER SER A . n 
A 1 282 ARG 282 271 271 ARG ARG A . n 
A 1 283 GLU 283 272 272 GLU GLU A . n 
A 1 284 LYS 284 273 273 LYS LYS A . n 
A 1 285 ASP 285 274 274 ASP ASP A . n 
A 1 286 ARG 286 275 275 ARG ARG A . n 
A 1 287 ASN 287 276 276 ASN ASN A . n 
A 1 288 LEU 288 277 277 LEU LEU A . n 
A 1 289 ARG 289 278 278 ARG ARG A . n 
A 1 290 ARG 290 279 279 ARG ARG A . n 
A 1 291 ILE 291 280 280 ILE ILE A . n 
A 1 292 THR 292 281 281 THR THR A . n 
A 1 293 ARG 293 282 282 ARG ARG A . n 
A 1 294 MET 294 283 283 MET MET A . n 
A 1 295 VAL 295 284 284 VAL VAL A . n 
A 1 296 LEU 296 285 285 LEU LEU A . n 
A 1 297 VAL 297 286 286 VAL VAL A . n 
A 1 298 VAL 298 287 287 VAL VAL A . n 
A 1 299 VAL 299 288 288 VAL VAL A . n 
A 1 300 ALA 300 289 289 ALA ALA A . n 
A 1 301 VAL 301 290 290 VAL VAL A . n 
A 1 302 PHE 302 291 291 PHE PHE A . n 
A 1 303 ILE 303 292 292 ILE ILE A . n 
A 1 304 VAL 304 293 293 VAL VAL A . n 
A 1 305 CYS 305 294 294 CYS CYS A . n 
A 1 306 TRP 306 295 295 TRP TRP A . n 
A 1 307 THR 307 296 296 THR THR A . n 
A 1 308 PRO 308 297 297 PRO PRO A . n 
A 1 309 ILE 309 298 298 ILE ILE A . n 
A 1 310 HIS 310 299 299 HIS HIS A . n 
A 1 311 ILE 311 300 300 ILE ILE A . n 
A 1 312 TYR 312 301 301 TYR TYR A . n 
A 1 313 VAL 313 302 302 VAL VAL A . n 
A 1 314 ILE 314 303 303 ILE ILE A . n 
A 1 315 ILE 315 304 304 ILE ILE A . n 
A 1 316 LYS 316 305 305 LYS LYS A . n 
A 1 317 ALA 317 306 306 ALA ALA A . n 
A 1 318 LEU 318 307 307 LEU LEU A . n 
A 1 319 VAL 319 308 308 VAL VAL A . n 
A 1 320 THR 320 309 309 THR THR A . n 
A 1 321 ILE 321 310 310 ILE ILE A . n 
A 1 322 PRO 322 311 311 PRO PRO A . n 
A 1 323 GLU 323 312 312 GLU GLU A . n 
A 1 324 THR 324 313 313 THR THR A . n 
A 1 325 THR 325 314 314 THR THR A . n 
A 1 326 PHE 326 315 315 PHE PHE A . n 
A 1 327 GLN 327 316 316 GLN GLN A . n 
A 1 328 THR 328 317 317 THR THR A . n 
A 1 329 VAL 329 318 318 VAL VAL A . n 
A 1 330 SER 330 319 319 SER SER A . n 
A 1 331 TRP 331 320 320 TRP TRP A . n 
A 1 332 HIS 332 321 321 HIS HIS A . n 
A 1 333 PHE 333 322 322 PHE PHE A . n 
A 1 334 CYS 334 323 323 CYS CYS A . n 
A 1 335 ILE 335 324 324 ILE ILE A . n 
A 1 336 ALA 336 325 325 ALA ALA A . n 
A 1 337 LEU 337 326 326 LEU LEU A . n 
A 1 338 GLY 338 327 327 GLY GLY A . n 
A 1 339 TYR 339 328 328 TYR TYR A . n 
A 1 340 THR 340 329 329 THR THR A . n 
A 1 341 ASN 341 330 330 ASN ASN A . n 
A 1 342 SER 342 331 331 SER SER A . n 
A 1 343 CYS 343 332 332 CYS CYS A . n 
A 1 344 LEU 344 333 333 LEU LEU A . n 
A 1 345 ASN 345 334 334 ASN ASN A . n 
A 1 346 PRO 346 335 335 PRO PRO A . n 
A 1 347 VAL 347 336 336 VAL VAL A . n 
A 1 348 LEU 348 337 337 LEU LEU A . n 
A 1 349 TYR 349 338 338 TYR TYR A . n 
A 1 350 ALA 350 339 339 ALA ALA A . n 
A 1 351 PHE 351 340 340 PHE PHE A . n 
A 1 352 LEU 352 341 341 LEU LEU A . n 
A 1 353 ASP 353 342 342 ASP ASP A . n 
A 1 354 GLU 354 343 343 GLU GLU A . n 
A 1 355 ASN 355 344 344 ASN ASN A . n 
A 1 356 PHE 356 345 345 PHE PHE A . n 
A 1 357 LYS 357 346 346 LYS LYS A . n 
A 1 358 ARG 358 347 347 ARG ARG A . n 
A 1 359 CYS 359 348 348 CYS CYS A . n 
A 1 360 PHE 360 349 349 PHE PHE A . n 
A 1 361 ARG 361 350 350 ARG ARG A . n 
A 1 362 GLU 362 351 351 GLU GLU A . n 
A 1 363 PHE 363 352 352 PHE PHE A . n 
A 1 364 CYS 364 353 353 CYS CYS A . n 
A 1 365 ILE 365 354 354 ILE ILE A . n 
A 1 366 PRO 366 355 ?   ?   ?   A . n 
A 1 367 THR 367 356 ?   ?   ?   A . n 
A 1 368 SER 368 357 ?   ?   ?   A . n 
A 1 369 SER 369 358 ?   ?   ?   A . n 
A 1 370 ASN 370 359 ?   ?   ?   A . n 
A 1 371 ILE 371 360 ?   ?   ?   A . n 
A 1 372 GLU 372 361 ?   ?   ?   A . n 
A 1 373 GLN 373 362 ?   ?   ?   A . n 
A 1 374 GLN 374 363 ?   ?   ?   A . n 
A 1 375 ASN 375 364 ?   ?   ?   A . n 
A 1 376 SER 376 365 ?   ?   ?   A . n 
A 1 377 THR 377 366 ?   ?   ?   A . n 
A 1 378 ARG 378 367 ?   ?   ?   A . n 
A 1 379 ILE 379 368 ?   ?   ?   A . n 
A 1 380 ARG 380 369 ?   ?   ?   A . n 
A 1 381 GLN 381 370 ?   ?   ?   A . n 
A 1 382 ASN 382 371 ?   ?   ?   A . n 
A 1 383 THR 383 372 ?   ?   ?   A . n 
A 1 384 ARG 384 373 ?   ?   ?   A . n 
A 1 385 ASP 385 374 ?   ?   ?   A . n 
A 1 386 HIS 386 375 ?   ?   ?   A . n 
A 1 387 PRO 387 376 ?   ?   ?   A . n 
A 1 388 SER 388 377 ?   ?   ?   A . n 
A 1 389 THR 389 378 ?   ?   ?   A . n 
A 1 390 ALA 390 379 ?   ?   ?   A . n 
A 1 391 ASN 391 380 ?   ?   ?   A . n 
A 1 392 THR 392 381 ?   ?   ?   A . n 
A 1 393 VAL 393 382 ?   ?   ?   A . n 
A 1 394 ASP 394 383 ?   ?   ?   A . n 
A 1 395 ARG 395 384 ?   ?   ?   A . n 
A 1 396 THR 396 385 ?   ?   ?   A . n 
A 1 397 ASN 397 386 ?   ?   ?   A . n 
A 1 398 HIS 398 387 ?   ?   ?   A . n 
A 1 399 GLN 399 388 ?   ?   ?   A . n 
A 1 400 LEU 400 389 ?   ?   ?   A . n 
A 1 401 GLU 401 390 ?   ?   ?   A . n 
A 1 402 ASN 402 391 ?   ?   ?   A . n 
A 1 403 LEU 403 392 ?   ?   ?   A . n 
A 1 404 GLU 404 393 ?   ?   ?   A . n 
A 1 405 ALA 405 394 ?   ?   ?   A . n 
A 1 406 GLU 406 395 ?   ?   ?   A . n 
A 1 407 THR 407 396 ?   ?   ?   A . n 
A 1 408 ALA 408 397 ?   ?   ?   A . n 
A 1 409 PRO 409 398 ?   ?   ?   A . n 
A 1 410 LEU 410 399 ?   ?   ?   A . n 
A 1 411 PRO 411 400 ?   ?   ?   A . n 
B 2 1   GLN 1   3   ?   ?   ?   C . n 
B 2 2   ARG 2   4   4   ARG ARG C . n 
B 2 3   GLN 3   5   5   GLN GLN C . n 
B 2 4   LEU 4   6   6   LEU LEU C . n 
B 2 5   VAL 5   7   7   VAL VAL C . n 
B 2 6   GLU 6   8   8   GLU GLU C . n 
B 2 7   SER 7   9   9   SER SER C . n 
B 2 8   GLY 8   10  10  GLY GLY C . n 
B 2 9   GLY 9   11  11  GLY GLY C . n 
B 2 10  GLY 10  12  12  GLY GLY C . n 
B 2 11  LEU 11  13  13  LEU LEU C . n 
B 2 12  VAL 12  14  14  VAL VAL C . n 
B 2 13  GLN 13  15  15  GLN GLN C . n 
B 2 14  PRO 14  16  16  PRO PRO C . n 
B 2 15  GLY 15  17  17  GLY GLY C . n 
B 2 16  GLY 16  18  18  GLY GLY C . n 
B 2 17  SER 17  19  19  SER SER C . n 
B 2 18  LEU 18  20  20  LEU LEU C . n 
B 2 19  ARG 19  21  21  ARG ARG C . n 
B 2 20  LEU 20  22  22  LEU LEU C . n 
B 2 21  SER 21  23  23  SER SER C . n 
B 2 22  CYS 22  24  24  CYS CYS C . n 
B 2 23  ALA 23  25  25  ALA ALA C . n 
B 2 24  ALA 24  26  26  ALA ALA C . n 
B 2 25  SER 25  27  27  SER SER C . n 
B 2 26  GLY 26  28  ?   ?   ?   C . n 
B 2 27  THR 27  29  ?   ?   ?   C . n 
B 2 28  ILE 28  30  ?   ?   ?   C . n 
B 2 29  PHE 29  31  31  PHE PHE C . n 
B 2 30  ARG 30  32  32  ARG ARG C . n 
B 2 31  LEU 31  33  33  LEU LEU C . n 
B 2 32  TYR 32  34  34  TYR TYR C . n 
B 2 33  ASP 33  35  35  ASP ASP C . n 
B 2 34  MET 34  36  36  MET MET C . n 
B 2 35  GLY 35  37  37  GLY GLY C . n 
B 2 36  TRP 36  38  38  TRP TRP C . n 
B 2 37  PHE 37  39  39  PHE PHE C . n 
B 2 38  ARG 38  40  40  ARG ARG C . n 
B 2 39  GLN 39  41  41  GLN GLN C . n 
B 2 40  ALA 40  42  42  ALA ALA C . n 
B 2 41  PRO 41  43  43  PRO PRO C . n 
B 2 42  GLY 42  44  44  GLY GLY C . n 
B 2 43  LYS 43  45  45  LYS LYS C . n 
B 2 44  GLU 44  46  46  GLU GLU C . n 
B 2 45  ARG 45  47  47  ARG ARG C . n 
B 2 46  GLU 46  48  48  GLU GLU C . n 
B 2 47  GLY 47  49  49  GLY GLY C . n 
B 2 48  VAL 48  50  50  VAL VAL C . n 
B 2 49  ALA 49  51  51  ALA ALA C . n 
B 2 50  SER 50  52  52  SER SER C . n 
B 2 51  ILE 51  53  53  ILE ILE C . n 
B 2 52  THR 52  54  54  THR THR C . n 
B 2 53  SER 53  55  55  SER SER C . n 
B 2 54  GLY 54  56  56  GLY GLY C . n 
B 2 55  GLY 55  57  57  GLY GLY C . n 
B 2 56  SER 56  58  58  SER SER C . n 
B 2 57  THR 57  59  59  THR THR C . n 
B 2 58  LYS 58  60  60  LYS LYS C . n 
B 2 59  TYR 59  61  61  TYR TYR C . n 
B 2 60  ALA 60  62  62  ALA ALA C . n 
B 2 61  ASP 61  63  63  ASP ASP C . n 
B 2 62  SER 62  64  64  SER SER C . n 
B 2 63  VAL 63  65  65  VAL VAL C . n 
B 2 64  LYS 64  66  66  LYS LYS C . n 
B 2 65  GLY 65  67  67  GLY GLY C . n 
B 2 66  ARG 66  68  68  ARG ARG C . n 
B 2 67  PHE 67  69  69  PHE PHE C . n 
B 2 68  THR 68  70  70  THR THR C . n 
B 2 69  ILE 69  71  71  ILE ILE C . n 
B 2 70  SER 70  72  72  SER SER C . n 
B 2 71  ARG 71  73  73  ARG ARG C . n 
B 2 72  ASP 72  74  74  ASP ASP C . n 
B 2 73  ASN 73  75  75  ASN ASN C . n 
B 2 74  ALA 74  76  76  ALA ALA C . n 
B 2 75  LYS 75  77  77  LYS LYS C . n 
B 2 76  ASN 76  78  78  ASN ASN C . n 
B 2 77  THR 77  79  79  THR THR C . n 
B 2 78  VAL 78  80  80  VAL VAL C . n 
B 2 79  TYR 79  81  81  TYR TYR C . n 
B 2 80  LEU 80  82  82  LEU LEU C . n 
B 2 81  GLN 81  83  83  GLN GLN C . n 
B 2 82  MET 82  84  84  MET MET C . n 
B 2 83  ASN 83  85  85  ASN ASN C . n 
B 2 84  SER 84  86  86  SER SER C . n 
B 2 85  LEU 85  87  87  LEU LEU C . n 
B 2 86  GLU 86  88  88  GLU GLU C . n 
B 2 87  PRO 87  89  89  PRO PRO C . n 
B 2 88  GLU 88  90  90  GLU GLU C . n 
B 2 89  ASP 89  91  91  ASP ASP C . n 
B 2 90  THR 90  92  92  THR THR C . n 
B 2 91  ALA 91  93  93  ALA ALA C . n 
B 2 92  VAL 92  94  94  VAL VAL C . n 
B 2 93  TYR 93  95  95  TYR TYR C . n 
B 2 94  TYR 94  96  96  TYR TYR C . n 
B 2 95  CYS 95  97  97  CYS CYS C . n 
B 2 96  ASN 96  98  98  ASN ASN C . n 
B 2 97  ALA 97  99  99  ALA ALA C . n 
B 2 98  GLU 98  100 100 GLU GLU C . n 
B 2 99  TYR 99  101 101 TYR TYR C . n 
B 2 100 ARG 100 102 102 ARG ARG C . n 
B 2 101 THR 101 103 103 THR THR C . n 
B 2 102 GLY 102 104 104 GLY GLY C . n 
B 2 103 ILE 103 105 105 ILE ILE C . n 
B 2 104 TRP 104 106 106 TRP TRP C . n 
B 2 105 GLU 105 107 107 GLU GLU C . n 
B 2 106 GLU 106 108 108 GLU GLU C . n 
B 2 107 LEU 107 109 109 LEU LEU C . n 
B 2 108 LEU 108 110 110 LEU LEU C . n 
B 2 109 ASP 109 111 111 ASP ASP C . n 
B 2 110 GLY 110 112 112 GLY GLY C . n 
B 2 111 TRP 111 113 113 TRP TRP C . n 
B 2 112 GLY 112 114 114 GLY GLY C . n 
B 2 113 LYS 113 115 115 LYS LYS C . n 
B 2 114 GLY 114 116 116 GLY GLY C . n 
B 2 115 THR 115 117 117 THR THR C . n 
B 2 116 PRO 116 118 118 PRO PRO C . n 
B 2 117 VAL 117 119 119 VAL VAL C . n 
B 2 118 THR 118 120 120 THR THR C . n 
B 2 119 VAL 119 121 121 VAL VAL C . n 
B 2 120 SER 120 122 122 SER SER C . n 
B 2 121 SER 121 123 123 SER SER C . n 
B 2 122 HIS 122 124 ?   ?   ?   C . n 
B 2 123 HIS 123 125 ?   ?   ?   C . n 
B 2 124 HIS 124 126 ?   ?   ?   C . n 
B 2 125 HIS 125 127 ?   ?   ?   C . n 
B 2 126 HIS 126 128 ?   ?   ?   C . n 
B 2 127 HIS 127 129 ?   ?   ?   C . n 
B 2 128 GLU 128 130 ?   ?   ?   C . n 
B 2 129 PRO 129 131 ?   ?   ?   C . n 
B 2 130 GLU 130 132 ?   ?   ?   C . n 
B 2 131 ALA 131 133 ?   ?   ?   C . n 
C 3 1   GLU 1   -2  ?   ?   ?   H . n 
C 3 2   ILE 2   -1  ?   ?   ?   H . n 
C 3 3   SER 3   0   ?   ?   ?   H . n 
C 3 4   GLU 4   1   ?   ?   ?   H . n 
C 3 5   VAL 5   2   2   VAL VAL H . n 
C 3 6   GLN 6   3   3   GLN GLN H . n 
C 3 7   LEU 7   4   4   LEU LEU H . n 
C 3 8   VAL 8   5   5   VAL VAL H . n 
C 3 9   GLU 9   6   6   GLU GLU H . n 
C 3 10  SER 10  7   7   SER SER H . n 
C 3 11  GLY 11  8   8   GLY GLY H . n 
C 3 12  GLY 12  9   9   GLY GLY H . n 
C 3 13  GLY 13  10  10  GLY GLY H . n 
C 3 14  LEU 14  11  11  LEU LEU H . n 
C 3 15  VAL 15  12  12  VAL VAL H . n 
C 3 16  GLN 16  13  13  GLN GLN H . n 
C 3 17  PRO 17  14  14  PRO PRO H . n 
C 3 18  GLY 18  15  15  GLY GLY H . n 
C 3 19  GLY 19  16  16  GLY GLY H . n 
C 3 20  SER 20  17  17  SER SER H . n 
C 3 21  LEU 21  18  18  LEU LEU H . n 
C 3 22  ARG 22  19  19  ARG ARG H . n 
C 3 23  LEU 23  20  20  LEU LEU H . n 
C 3 24  SER 24  21  21  SER SER H . n 
C 3 25  CYS 25  22  22  CYS CYS H . n 
C 3 26  ALA 26  23  23  ALA ALA H . n 
C 3 27  ALA 27  24  24  ALA ALA H . n 
C 3 28  SER 28  25  25  SER SER H . n 
C 3 29  GLY 29  26  26  GLY GLY H . n 
C 3 30  PHE 30  27  27  PHE PHE H . n 
C 3 31  ASN 31  28  28  ASN ASN H . n 
C 3 32  PHE 32  29  29  PHE PHE H . n 
C 3 33  SER 33  30  30  SER SER H . n 
C 3 34  TYR 34  31  31  TYR TYR H . n 
C 3 35  TYR 35  32  32  TYR TYR H . n 
C 3 36  SER 36  33  33  SER SER H . n 
C 3 37  ILE 37  34  34  ILE ILE H . n 
C 3 38  HIS 38  35  35  HIS HIS H . n 
C 3 39  TRP 39  36  36  TRP TRP H . n 
C 3 40  VAL 40  37  37  VAL VAL H . n 
C 3 41  ARG 41  38  38  ARG ARG H . n 
C 3 42  GLN 42  39  39  GLN GLN H . n 
C 3 43  ALA 43  40  40  ALA ALA H . n 
C 3 44  PRO 44  41  41  PRO PRO H . n 
C 3 45  GLY 45  42  42  GLY GLY H . n 
C 3 46  LYS 46  43  43  LYS LYS H . n 
C 3 47  GLY 47  44  44  GLY GLY H . n 
C 3 48  LEU 48  45  45  LEU LEU H . n 
C 3 49  GLU 49  46  46  GLU GLU H . n 
C 3 50  TRP 50  47  47  TRP TRP H . n 
C 3 51  VAL 51  48  48  VAL VAL H . n 
C 3 52  ALA 52  49  49  ALA ALA H . n 
C 3 53  TYR 53  50  50  TYR TYR H . n 
C 3 54  ILE 54  51  51  ILE ILE H . n 
C 3 55  SER 55  51  ?   ?   ?   H A n 
C 3 56  SER 56  51  ?   ?   ?   H B n 
C 3 57  SER 57  51  ?   ?   ?   H C n 
C 3 58  SER 58  51  ?   ?   ?   H D n 
C 3 59  SER 59  51  ?   ?   ?   H E n 
C 3 60  TYR 60  56  56  TYR TYR H . n 
C 3 61  THR 61  57  57  THR THR H . n 
C 3 62  SER 62  58  58  SER SER H . n 
C 3 63  TYR 63  59  59  TYR TYR H . n 
C 3 64  ALA 64  60  60  ALA ALA H . n 
C 3 65  ASP 65  61  61  ASP ASP H . n 
C 3 66  SER 66  62  ?   ?   ?   H . n 
C 3 67  VAL 67  63  63  VAL VAL H . n 
C 3 68  LYS 68  64  64  LYS LYS H . n 
C 3 69  GLY 69  65  65  GLY GLY H . n 
C 3 70  ARG 70  66  66  ARG ARG H . n 
C 3 71  PHE 71  67  67  PHE PHE H . n 
C 3 72  THR 72  68  68  THR THR H . n 
C 3 73  ILE 73  69  69  ILE ILE H . n 
C 3 74  SER 74  70  70  SER SER H . n 
C 3 75  ALA 75  71  71  ALA ALA H . n 
C 3 76  ASP 76  72  72  ASP ASP H . n 
C 3 77  THR 77  73  ?   ?   ?   H . n 
C 3 78  SER 78  74  ?   ?   ?   H . n 
C 3 79  LYS 79  75  ?   ?   ?   H . n 
C 3 80  ASN 80  76  76  ASN ASN H . n 
C 3 81  THR 81  77  77  THR THR H . n 
C 3 82  ALA 82  78  78  ALA ALA H . n 
C 3 83  TYR 83  79  79  TYR TYR H . n 
C 3 84  LEU 84  80  80  LEU LEU H . n 
C 3 85  GLN 85  81  81  GLN GLN H . n 
C 3 86  MET 86  82  82  MET MET H . n 
C 3 87  ASN 87  83  83  ASN ASN H . n 
C 3 88  SER 88  84  84  SER SER H . n 
C 3 89  LEU 89  85  85  LEU LEU H . n 
C 3 90  ARG 90  86  86  ARG ARG H . n 
C 3 91  ALA 91  87  87  ALA ALA H . n 
C 3 92  GLU 92  88  88  GLU GLU H . n 
C 3 93  ASP 93  89  89  ASP ASP H . n 
C 3 94  THR 94  90  90  THR THR H . n 
C 3 95  ALA 95  91  91  ALA ALA H . n 
C 3 96  VAL 96  92  92  VAL VAL H . n 
C 3 97  TYR 97  93  93  TYR TYR H . n 
C 3 98  TYR 98  94  94  TYR TYR H . n 
C 3 99  CYS 99  95  95  CYS CYS H . n 
C 3 100 ALA 100 96  96  ALA ALA H . n 
C 3 101 ARG 101 97  97  ARG ARG H . n 
C 3 102 GLY 102 98  98  GLY GLY H . n 
C 3 103 TYR 103 99  99  TYR TYR H . n 
C 3 104 GLN 104 100 100 GLN GLN H . n 
C 3 105 TYR 105 101 101 TYR TYR H . n 
C 3 106 TRP 106 102 102 TRP TRP H . n 
C 3 107 GLN 107 103 103 GLN GLN H . n 
C 3 108 TYR 108 104 104 TYR TYR H . n 
C 3 109 HIS 109 105 105 HIS HIS H . n 
C 3 110 ALA 110 106 106 ALA ALA H . n 
C 3 111 SER 111 107 107 SER SER H . n 
C 3 112 TRP 112 108 108 TRP TRP H . n 
C 3 113 TYR 113 109 109 TYR TYR H . n 
C 3 114 TRP 114 110 110 TRP TRP H . n 
C 3 115 ASN 115 111 111 ASN ASN H . n 
C 3 116 GLY 116 112 112 GLY GLY H . n 
C 3 117 GLY 117 113 113 GLY GLY H . n 
C 3 118 LEU 118 114 114 LEU LEU H . n 
C 3 119 ASP 119 115 115 ASP ASP H . n 
C 3 120 TYR 120 116 116 TYR TYR H . n 
C 3 121 TRP 121 117 117 TRP TRP H . n 
C 3 122 GLY 122 118 118 GLY GLY H . n 
C 3 123 GLN 123 119 119 GLN GLN H . n 
C 3 124 GLY 124 120 120 GLY GLY H . n 
C 3 125 THR 125 121 121 THR THR H . n 
C 3 126 LEU 126 122 122 LEU LEU H . n 
C 3 127 VAL 127 123 123 VAL VAL H . n 
C 3 128 THR 128 124 124 THR THR H . n 
C 3 129 VAL 129 125 125 VAL VAL H . n 
C 3 130 SER 130 126 126 SER SER H . n 
C 3 131 SER 131 127 127 SER SER H . n 
C 3 132 ALA 132 128 128 ALA ALA H . n 
C 3 133 SER 133 129 129 SER SER H . n 
C 3 134 THR 134 130 130 THR THR H . n 
C 3 135 LYS 135 131 131 LYS LYS H . n 
C 3 136 GLY 136 132 132 GLY GLY H . n 
C 3 137 PRO 137 133 133 PRO PRO H . n 
C 3 138 SER 138 134 134 SER SER H . n 
C 3 139 VAL 139 135 135 VAL VAL H . n 
C 3 140 PHE 140 136 136 PHE PHE H . n 
C 3 141 PRO 141 137 137 PRO PRO H . n 
C 3 142 LEU 142 138 138 LEU LEU H . n 
C 3 143 ALA 143 139 139 ALA ALA H . n 
C 3 144 PRO 144 140 140 PRO PRO H . n 
C 3 145 SER 145 141 141 SER SER H . n 
C 3 146 SER 146 141 ?   ?   ?   H A n 
C 3 147 LYS 147 141 ?   ?   ?   H B n 
C 3 148 SER 148 141 ?   ?   ?   H C n 
C 3 149 THR 149 141 ?   ?   ?   H D n 
C 3 150 SER 150 141 ?   ?   ?   H E n 
C 3 151 GLY 151 141 ?   ?   ?   H F n 
C 3 152 GLY 152 141 ?   ?   ?   H G n 
C 3 153 THR 153 142 142 THR THR H . n 
C 3 154 ALA 154 143 143 ALA ALA H . n 
C 3 155 ALA 155 144 144 ALA ALA H . n 
C 3 156 LEU 156 145 145 LEU LEU H . n 
C 3 157 GLY 157 146 146 GLY GLY H . n 
C 3 158 CYS 158 147 147 CYS CYS H . n 
C 3 159 LEU 159 148 148 LEU LEU H . n 
C 3 160 VAL 160 149 149 VAL VAL H . n 
C 3 161 LYS 161 150 150 LYS LYS H . n 
C 3 162 ASP 162 151 151 ASP ASP H . n 
C 3 163 TYR 163 152 152 TYR TYR H . n 
C 3 164 PHE 164 152 ?   ?   ?   H A n 
C 3 165 PRO 165 152 ?   ?   ?   H B n 
C 3 166 GLU 166 152 ?   ?   ?   H C n 
C 3 167 PRO 167 152 ?   ?   ?   H D n 
C 3 168 VAL 168 153 153 VAL VAL H . n 
C 3 169 THR 169 154 154 THR THR H . n 
C 3 170 VAL 170 155 155 VAL VAL H . n 
C 3 171 SER 171 156 156 SER SER H . n 
C 3 172 TRP 172 157 157 TRP TRP H . n 
C 3 173 ASN 173 157 ?   ?   ?   H A n 
C 3 174 SER 174 157 ?   ?   ?   H B n 
C 3 175 GLY 175 157 ?   ?   ?   H C n 
C 3 176 ALA 176 157 ?   ?   ?   H D n 
C 3 177 LEU 177 157 ?   ?   ?   H E n 
C 3 178 THR 178 157 ?   ?   ?   H F n 
C 3 179 SER 179 157 ?   ?   ?   H G n 
C 3 180 GLY 180 157 ?   ?   ?   H H n 
C 3 181 VAL 181 163 163 VAL VAL H . n 
C 3 182 HIS 182 164 164 HIS HIS H . n 
C 3 183 THR 183 165 165 THR THR H . n 
C 3 184 PHE 184 166 166 PHE PHE H . n 
C 3 185 PRO 185 167 167 PRO PRO H . n 
C 3 186 ALA 186 168 168 ALA ALA H . n 
C 3 187 VAL 187 169 169 VAL VAL H . n 
C 3 188 LEU 188 170 170 LEU LEU H . n 
C 3 189 GLN 189 171 171 GLN GLN H . n 
C 3 190 SER 190 172 172 SER SER H . n 
C 3 191 SER 191 173 ?   ?   ?   H . n 
C 3 192 GLY 192 174 ?   ?   ?   H . n 
C 3 193 LEU 193 175 ?   ?   ?   H . n 
C 3 194 TYR 194 176 ?   ?   ?   H . n 
C 3 195 SER 195 177 177 SER SER H . n 
C 3 196 LEU 196 178 178 LEU LEU H . n 
C 3 197 SER 197 179 179 SER SER H . n 
C 3 198 SER 198 180 180 SER SER H . n 
C 3 199 VAL 199 181 181 VAL VAL H . n 
C 3 200 VAL 200 182 182 VAL VAL H . n 
C 3 201 THR 201 183 183 THR THR H . n 
C 3 202 VAL 202 184 ?   ?   ?   H . n 
C 3 203 PRO 203 185 ?   ?   ?   H . n 
C 3 204 SER 204 186 ?   ?   ?   H . n 
C 3 205 SER 205 187 ?   ?   ?   H . n 
C 3 206 SER 206 188 ?   ?   ?   H . n 
C 3 207 LEU 207 189 ?   ?   ?   H . n 
C 3 208 GLY 208 190 ?   ?   ?   H . n 
C 3 209 THR 209 191 ?   ?   ?   H . n 
C 3 210 GLN 210 192 ?   ?   ?   H . n 
C 3 211 THR 211 193 ?   ?   ?   H . n 
C 3 212 TYR 212 194 194 TYR TYR H . n 
C 3 213 ILE 213 195 195 ILE ILE H . n 
C 3 214 CYS 214 196 196 CYS CYS H . n 
C 3 215 ASN 215 197 197 ASN ASN H . n 
C 3 216 VAL 216 198 198 VAL VAL H . n 
C 3 217 ASN 217 199 199 ASN ASN H . n 
C 3 218 HIS 218 200 200 HIS HIS H . n 
C 3 219 LYS 219 201 201 LYS LYS H . n 
C 3 220 PRO 220 202 202 PRO PRO H . n 
C 3 221 SER 221 203 203 SER SER H . n 
C 3 222 ASN 222 204 204 ASN ASN H . n 
C 3 223 THR 223 205 205 THR THR H . n 
C 3 224 LYS 224 206 206 LYS LYS H . n 
C 3 225 VAL 225 207 207 VAL VAL H . n 
C 3 226 ASP 226 208 ?   ?   ?   H . n 
C 3 227 LYS 227 209 ?   ?   ?   H . n 
C 3 228 LYS 228 210 210 LYS LYS H . n 
C 3 229 VAL 229 211 211 VAL VAL H . n 
C 3 230 GLU 230 212 212 GLU GLU H . n 
C 3 231 PRO 231 213 213 PRO PRO H . n 
C 3 232 LYS 232 214 ?   ?   ?   H . n 
C 3 233 SER 233 215 ?   ?   ?   H . n 
C 3 234 CYS 234 216 ?   ?   ?   H . n 
C 3 235 ASP 235 217 ?   ?   ?   H . n 
C 3 236 LYS 236 218 ?   ?   ?   H . n 
C 3 237 THR 237 219 ?   ?   ?   H . n 
C 3 238 HIS 238 220 ?   ?   ?   H . n 
C 3 239 THR 239 221 ?   ?   ?   H . n 
D 4 1   SER 1   0   ?   ?   ?   L . n 
D 4 2   ASP 2   1   ?   ?   ?   L . n 
D 4 3   ILE 3   2   ?   ?   ?   L . n 
D 4 4   GLN 4   3   ?   ?   ?   L . n 
D 4 5   MET 5   4   ?   ?   ?   L . n 
D 4 6   THR 6   5   5   THR THR L . n 
D 4 7   GLN 7   6   6   GLN GLN L . n 
D 4 8   SER 8   7   ?   ?   ?   L . n 
D 4 9   PRO 9   8   ?   ?   ?   L . n 
D 4 10  SER 10  9   9   SER SER L . n 
D 4 11  SER 11  10  10  SER SER L . n 
D 4 12  LEU 12  11  11  LEU LEU L . n 
D 4 13  SER 13  12  12  SER SER L . n 
D 4 14  ALA 14  13  13  ALA ALA L . n 
D 4 15  SER 15  14  14  SER SER L . n 
D 4 16  VAL 16  15  15  VAL VAL L . n 
D 4 17  GLY 17  16  16  GLY GLY L . n 
D 4 18  ASP 18  17  17  ASP ASP L . n 
D 4 19  ARG 19  18  18  ARG ARG L . n 
D 4 20  VAL 20  19  ?   ?   ?   L . n 
D 4 21  THR 21  20  20  THR THR L . n 
D 4 22  ILE 22  21  21  ILE ILE L . n 
D 4 23  THR 23  22  22  THR THR L . n 
D 4 24  CYS 24  23  23  CYS CYS L . n 
D 4 25  ARG 25  24  24  ARG ARG L . n 
D 4 26  ALA 26  25  25  ALA ALA L . n 
D 4 27  SER 27  26  ?   ?   ?   L . n 
D 4 28  GLN 28  27  ?   ?   ?   L . n 
D 4 29  SER 29  28  ?   ?   ?   L . n 
D 4 30  VAL 30  29  ?   ?   ?   L . n 
D 4 31  SER 31  30  30  SER SER L . n 
D 4 32  SER 32  31  31  SER SER L . n 
D 4 33  ALA 33  32  32  ALA ALA L . n 
D 4 34  VAL 34  33  33  VAL VAL L . n 
D 4 35  ALA 35  34  34  ALA ALA L . n 
D 4 36  TRP 36  35  35  TRP TRP L . n 
D 4 37  TYR 37  36  36  TYR TYR L . n 
D 4 38  GLN 38  37  37  GLN GLN L . n 
D 4 39  GLN 39  38  38  GLN GLN L . n 
D 4 40  LYS 40  39  39  LYS LYS L . n 
D 4 41  PRO 41  40  40  PRO PRO L . n 
D 4 42  GLY 42  41  41  GLY GLY L . n 
D 4 43  LYS 43  42  42  LYS LYS L . n 
D 4 44  ALA 44  43  43  ALA ALA L . n 
D 4 45  PRO 45  44  44  PRO PRO L . n 
D 4 46  LYS 46  45  45  LYS LYS L . n 
D 4 47  LEU 47  46  46  LEU LEU L . n 
D 4 48  LEU 48  47  47  LEU LEU L . n 
D 4 49  ILE 49  48  48  ILE ILE L . n 
D 4 50  TYR 50  49  49  TYR TYR L . n 
D 4 51  SER 51  50  50  SER SER L . n 
D 4 52  ALA 52  51  51  ALA ALA L . n 
D 4 53  SER 53  52  52  SER SER L . n 
D 4 54  SER 54  53  53  SER SER L . n 
D 4 55  LEU 55  54  54  LEU LEU L . n 
D 4 56  TYR 56  55  55  TYR TYR L . n 
D 4 57  SER 57  56  56  SER SER L . n 
D 4 58  GLY 58  57  57  GLY GLY L . n 
D 4 59  VAL 59  58  58  VAL VAL L . n 
D 4 60  PRO 60  59  59  PRO PRO L . n 
D 4 61  SER 61  60  60  SER SER L . n 
D 4 62  ARG 62  61  61  ARG ARG L . n 
D 4 63  PHE 63  62  62  PHE PHE L . n 
D 4 64  SER 64  63  63  SER SER L . n 
D 4 65  GLY 65  64  64  GLY GLY L . n 
D 4 66  SER 66  65  65  SER SER L . n 
D 4 67  ARG 67  66  66  ARG ARG L . n 
D 4 68  SER 68  67  ?   ?   ?   L . n 
D 4 69  GLY 69  68  68  GLY GLY L . n 
D 4 70  THR 70  69  69  THR THR L . n 
D 4 71  ASP 71  70  70  ASP ASP L . n 
D 4 72  PHE 72  71  71  PHE PHE L . n 
D 4 73  THR 73  72  72  THR THR L . n 
D 4 74  LEU 74  73  73  LEU LEU L . n 
D 4 75  THR 75  74  74  THR THR L . n 
D 4 76  ILE 76  75  75  ILE ILE L . n 
D 4 77  SER 77  76  76  SER SER L . n 
D 4 78  SER 78  77  77  SER SER L . n 
D 4 79  LEU 79  78  78  LEU LEU L . n 
D 4 80  GLN 80  79  79  GLN GLN L . n 
D 4 81  PRO 81  80  80  PRO PRO L . n 
D 4 82  GLU 82  81  81  GLU GLU L . n 
D 4 83  ASP 83  82  82  ASP ASP L . n 
D 4 84  PHE 84  83  83  PHE PHE L . n 
D 4 85  ALA 85  84  84  ALA ALA L . n 
D 4 86  THR 86  85  85  THR THR L . n 
D 4 87  TYR 87  86  86  TYR TYR L . n 
D 4 88  TYR 88  87  87  TYR TYR L . n 
D 4 89  CYS 89  88  88  CYS CYS L . n 
D 4 90  GLN 90  89  89  GLN GLN L . n 
D 4 91  GLN 91  90  90  GLN GLN L . n 
D 4 92  SER 92  91  91  SER SER L . n 
D 4 93  SER 93  92  92  SER SER L . n 
D 4 94  SER 94  93  93  SER SER L . n 
D 4 95  SER 95  94  94  SER SER L . n 
D 4 96  LEU 96  95  95  LEU LEU L . n 
D 4 97  ILE 97  96  96  ILE ILE L . n 
D 4 98  THR 98  97  97  THR THR L . n 
D 4 99  PHE 99  98  98  PHE PHE L . n 
D 4 100 GLY 100 99  99  GLY GLY L . n 
D 4 101 GLN 101 100 100 GLN GLN L . n 
D 4 102 GLY 102 101 101 GLY GLY L . n 
D 4 103 THR 103 102 102 THR THR L . n 
D 4 104 LYS 104 103 103 LYS LYS L . n 
D 4 105 VAL 105 104 104 VAL VAL L . n 
D 4 106 GLU 106 105 105 GLU GLU L . n 
D 4 107 ILE 107 106 106 ILE ILE L . n 
D 4 108 LYS 108 107 107 LYS LYS L . n 
D 4 109 ARG 109 108 108 ARG ARG L . n 
D 4 110 THR 110 109 109 THR THR L . n 
D 4 111 VAL 111 110 110 VAL VAL L . n 
D 4 112 ALA 112 111 111 ALA ALA L . n 
D 4 113 ALA 113 112 112 ALA ALA L . n 
D 4 114 PRO 114 113 113 PRO PRO L . n 
D 4 115 SER 115 114 114 SER SER L . n 
D 4 116 VAL 116 115 115 VAL VAL L . n 
D 4 117 PHE 117 116 116 PHE PHE L . n 
D 4 118 ILE 118 117 117 ILE ILE L . n 
D 4 119 PHE 119 118 118 PHE PHE L . n 
D 4 120 PRO 120 119 119 PRO PRO L . n 
D 4 121 PRO 121 120 120 PRO PRO L . n 
D 4 122 SER 122 121 121 SER SER L . n 
D 4 123 ASP 123 122 122 ASP ASP L . n 
D 4 124 SER 124 123 123 SER SER L . n 
D 4 125 GLN 125 124 124 GLN GLN L . n 
D 4 126 LEU 126 125 125 LEU LEU L . n 
D 4 127 LYS 127 126 126 LYS LYS L . n 
D 4 128 SER 128 127 127 SER SER L . n 
D 4 129 GLY 129 128 128 GLY GLY L . n 
D 4 130 THR 130 129 129 THR THR L . n 
D 4 131 ALA 131 130 130 ALA ALA L . n 
D 4 132 SER 132 131 131 SER SER L . n 
D 4 133 VAL 133 132 132 VAL VAL L . n 
D 4 134 VAL 134 133 133 VAL VAL L . n 
D 4 135 CYS 135 134 134 CYS CYS L . n 
D 4 136 LEU 136 135 135 LEU LEU L . n 
D 4 137 LEU 137 136 136 LEU LEU L . n 
D 4 138 ASN 138 137 137 ASN ASN L . n 
D 4 139 ASN 139 138 138 ASN ASN L . n 
D 4 140 PHE 140 139 139 PHE PHE L . n 
D 4 141 TYR 141 140 140 TYR TYR L . n 
D 4 142 PRO 142 141 141 PRO PRO L . n 
D 4 143 ARG 143 142 142 ARG ARG L . n 
D 4 144 GLU 144 143 143 GLU GLU L . n 
D 4 145 ALA 145 144 144 ALA ALA L . n 
D 4 146 LYS 146 145 145 LYS LYS L . n 
D 4 147 VAL 147 146 146 VAL VAL L . n 
D 4 148 GLN 148 147 147 GLN GLN L . n 
D 4 149 TRP 149 148 148 TRP TRP L . n 
D 4 150 LYS 150 149 149 LYS LYS L . n 
D 4 151 VAL 151 150 150 VAL VAL L . n 
D 4 152 ASP 152 151 151 ASP ASP L . n 
D 4 153 ASN 153 152 152 ASN ASN L . n 
D 4 154 ALA 154 153 153 ALA ALA L . n 
D 4 155 LEU 155 154 154 LEU LEU L . n 
D 4 156 GLN 156 155 155 GLN GLN L . n 
D 4 157 SER 157 156 156 SER SER L . n 
D 4 158 GLY 158 157 157 GLY GLY L . n 
D 4 159 ASN 159 158 158 ASN ASN L . n 
D 4 160 SER 160 159 159 SER SER L . n 
D 4 161 GLN 161 160 160 GLN GLN L . n 
D 4 162 GLU 162 161 161 GLU GLU L . n 
D 4 163 SER 163 162 162 SER SER L . n 
D 4 164 VAL 164 163 163 VAL VAL L . n 
D 4 165 THR 165 164 164 THR THR L . n 
D 4 166 GLU 166 165 165 GLU GLU L . n 
D 4 167 GLN 167 166 166 GLN GLN L . n 
D 4 168 ASP 168 167 167 ASP ASP L . n 
D 4 169 SER 169 168 168 SER SER L . n 
D 4 170 LYS 170 169 169 LYS LYS L . n 
D 4 171 ASP 171 170 170 ASP ASP L . n 
D 4 172 SER 172 171 171 SER SER L . n 
D 4 173 THR 173 172 172 THR THR L . n 
D 4 174 TYR 174 173 173 TYR TYR L . n 
D 4 175 SER 175 174 174 SER SER L . n 
D 4 176 LEU 176 175 175 LEU LEU L . n 
D 4 177 SER 177 176 176 SER SER L . n 
D 4 178 SER 178 177 177 SER SER L . n 
D 4 179 THR 179 178 178 THR THR L . n 
D 4 180 LEU 180 179 179 LEU LEU L . n 
D 4 181 THR 181 180 180 THR THR L . n 
D 4 182 LEU 182 181 181 LEU LEU L . n 
D 4 183 SER 183 182 182 SER SER L . n 
D 4 184 LYS 184 183 183 LYS LYS L . n 
D 4 185 ALA 185 184 184 ALA ALA L . n 
D 4 186 ASP 186 185 185 ASP ASP L . n 
D 4 187 TYR 187 186 186 TYR TYR L . n 
D 4 188 GLU 188 187 187 GLU GLU L . n 
D 4 189 LYS 189 188 188 LYS LYS L . n 
D 4 190 HIS 190 189 189 HIS HIS L . n 
D 4 191 LYS 191 190 190 LYS LYS L . n 
D 4 192 VAL 192 191 191 VAL VAL L . n 
D 4 193 TYR 193 192 192 TYR TYR L . n 
D 4 194 ALA 194 193 193 ALA ALA L . n 
D 4 195 CYS 195 194 194 CYS CYS L . n 
D 4 196 GLU 196 195 195 GLU GLU L . n 
D 4 197 VAL 197 196 196 VAL VAL L . n 
D 4 198 THR 198 197 197 THR THR L . n 
D 4 199 HIS 199 198 198 HIS HIS L . n 
D 4 200 GLN 200 199 199 GLN GLN L . n 
D 4 201 GLY 201 200 200 GLY GLY L . n 
D 4 202 LEU 202 201 201 LEU LEU L . n 
D 4 203 SER 203 202 202 SER SER L . n 
D 4 204 SER 204 203 203 SER SER L . n 
D 4 205 PRO 205 204 204 PRO PRO L . n 
D 4 206 VAL 206 205 205 VAL VAL L . n 
D 4 207 THR 207 206 206 THR THR L . n 
D 4 208 LYS 208 207 207 LYS LYS L . n 
D 4 209 SER 209 208 208 SER SER L . n 
D 4 210 PHE 210 209 209 PHE PHE L . n 
D 4 211 ASN 211 210 210 ASN ASN L . n 
D 4 212 ARG 212 211 211 ARG ARG L . n 
D 4 213 GLY 213 212 ?   ?   ?   L . n 
D 4 214 GLU 214 213 ?   ?   ?   L . n 
D 4 215 CYS 215 214 ?   ?   ?   L . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1BNM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1BNM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         E 
_pdbx_nonpoly_scheme.entity_id       5 
_pdbx_nonpoly_scheme.mon_id          A1BNM 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    1 
_pdbx_nonpoly_scheme.pdb_mon_id      A1BNM 
_pdbx_nonpoly_scheme.auth_mon_id     A1 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A MET 67  ? CG  ? A MET 78  CG  
2   1 Y 1 A MET 67  ? SD  ? A MET 78  SD  
3   1 Y 1 A MET 67  ? CE  ? A MET 78  CE  
4   1 Y 1 A THR 69  ? OG1 ? A THR 80  OG1 
5   1 Y 1 A THR 69  ? CG2 ? A THR 80  CG2 
6   1 Y 1 A ILE 79  ? CG1 ? A ILE 90  CG1 
7   1 Y 1 A ILE 79  ? CG2 ? A ILE 90  CG2 
8   1 Y 1 A ILE 79  ? CD1 ? A ILE 90  CD1 
9   1 Y 1 A PHE 86  ? CG  ? A PHE 97  CG  
10  1 Y 1 A PHE 86  ? CD1 ? A PHE 97  CD1 
11  1 Y 1 A PHE 86  ? CD2 ? A PHE 97  CD2 
12  1 Y 1 A PHE 86  ? CE1 ? A PHE 97  CE1 
13  1 Y 1 A PHE 86  ? CE2 ? A PHE 97  CE2 
14  1 Y 1 A PHE 86  ? CZ  ? A PHE 97  CZ  
15  1 Y 1 A MET 92  ? CG  ? A MET 103 CG  
16  1 Y 1 A MET 92  ? SD  ? A MET 103 SD  
17  1 Y 1 A MET 92  ? CE  ? A MET 103 CE  
18  1 Y 1 A VAL 96  ? CG1 ? A VAL 107 CG1 
19  1 Y 1 A VAL 96  ? CG2 ? A VAL 107 CG2 
20  1 Y 1 A ARG 97  ? CG  ? A ARG 108 CG  
21  1 Y 1 A ARG 97  ? CD  ? A ARG 108 CD  
22  1 Y 1 A ARG 97  ? NE  ? A ARG 108 NE  
23  1 Y 1 A ARG 97  ? CZ  ? A ARG 108 CZ  
24  1 Y 1 A ARG 97  ? NH1 ? A ARG 108 NH1 
25  1 Y 1 A ARG 97  ? NH2 ? A ARG 108 NH2 
26  1 Y 1 A TYR 98  ? CG  ? A TYR 109 CG  
27  1 Y 1 A TYR 98  ? CD1 ? A TYR 109 CD1 
28  1 Y 1 A TYR 98  ? CD2 ? A TYR 109 CD2 
29  1 Y 1 A TYR 98  ? CE1 ? A TYR 109 CE1 
30  1 Y 1 A TYR 98  ? CE2 ? A TYR 109 CE2 
31  1 Y 1 A TYR 98  ? CZ  ? A TYR 109 CZ  
32  1 Y 1 A TYR 98  ? OH  ? A TYR 109 OH  
33  1 Y 1 A THR 99  ? OG1 ? A THR 110 OG1 
34  1 Y 1 A THR 99  ? CG2 ? A THR 110 CG2 
35  1 Y 1 A LYS 100 ? CG  ? A LYS 111 CG  
36  1 Y 1 A LYS 100 ? CD  ? A LYS 111 CD  
37  1 Y 1 A LYS 100 ? CE  ? A LYS 111 CE  
38  1 Y 1 A LYS 100 ? NZ  ? A LYS 111 NZ  
39  1 Y 1 A LYS 102 ? CG  ? A LYS 113 CG  
40  1 Y 1 A LYS 102 ? CD  ? A LYS 113 CD  
41  1 Y 1 A LYS 102 ? CE  ? A LYS 113 CE  
42  1 Y 1 A LYS 102 ? NZ  ? A LYS 113 NZ  
43  1 Y 1 A VAL 128 ? CG1 ? A VAL 139 CG1 
44  1 Y 1 A VAL 128 ? CG2 ? A VAL 139 CG2 
45  1 Y 1 A LEU 131 ? CG  ? A LEU 142 CG  
46  1 Y 1 A LEU 131 ? CD1 ? A LEU 142 CD1 
47  1 Y 1 A LEU 131 ? CD2 ? A LEU 142 CD2 
48  1 Y 1 A VAL 175 ? CG1 ? A VAL 186 CG1 
49  1 Y 1 A VAL 175 ? CG2 ? A VAL 186 CG2 
50  1 Y 1 A LYS 176 ? CG  ? A LYS 187 CG  
51  1 Y 1 A LYS 176 ? CD  ? A LYS 187 CD  
52  1 Y 1 A LYS 176 ? CE  ? A LYS 187 CE  
53  1 Y 1 A LYS 176 ? NZ  ? A LYS 187 NZ  
54  1 Y 1 A LEU 178 ? CG  ? A LEU 189 CG  
55  1 Y 1 A LEU 178 ? CD1 ? A LEU 189 CD1 
56  1 Y 1 A LEU 178 ? CD2 ? A LEU 189 CD2 
57  1 Y 1 A ASP 179 ? CG  ? A ASP 190 CG  
58  1 Y 1 A ASP 179 ? OD1 ? A ASP 190 OD1 
59  1 Y 1 A ASP 179 ? OD2 ? A ASP 190 OD2 
60  1 Y 1 A ARG 184 ? CG  ? A ARG 195 CG  
61  1 Y 1 A ARG 184 ? CD  ? A ARG 195 CD  
62  1 Y 1 A ARG 184 ? NE  ? A ARG 195 NE  
63  1 Y 1 A ARG 184 ? CZ  ? A ARG 195 CZ  
64  1 Y 1 A ARG 184 ? NH1 ? A ARG 195 NH1 
65  1 Y 1 A ARG 184 ? NH2 ? A ARG 195 NH2 
66  1 Y 1 A ILE 200 ? CG1 ? A ILE 211 CG1 
67  1 Y 1 A ILE 200 ? CG2 ? A ILE 211 CG2 
68  1 Y 1 A ILE 200 ? CD1 ? A ILE 211 CD1 
69  1 Y 1 A LYS 211 ? CG  ? A LYS 222 CG  
70  1 Y 1 A LYS 211 ? CD  ? A LYS 222 CD  
71  1 Y 1 A LYS 211 ? CE  ? A LYS 222 CE  
72  1 Y 1 A LYS 211 ? NZ  ? A LYS 222 NZ  
73  1 Y 1 A TYR 212 ? CG  ? A TYR 223 CG  
74  1 Y 1 A TYR 212 ? CD1 ? A TYR 223 CD1 
75  1 Y 1 A TYR 212 ? CD2 ? A TYR 223 CD2 
76  1 Y 1 A TYR 212 ? CE1 ? A TYR 223 CE1 
77  1 Y 1 A TYR 212 ? CE2 ? A TYR 223 CE2 
78  1 Y 1 A TYR 212 ? CZ  ? A TYR 223 CZ  
79  1 Y 1 A TYR 212 ? OH  ? A TYR 223 OH  
80  1 Y 1 A ARG 213 ? CG  ? A ARG 224 CG  
81  1 Y 1 A ARG 213 ? CD  ? A ARG 224 CD  
82  1 Y 1 A ARG 213 ? NE  ? A ARG 224 NE  
83  1 Y 1 A ARG 213 ? CZ  ? A ARG 224 CZ  
84  1 Y 1 A ARG 213 ? NH1 ? A ARG 224 NH1 
85  1 Y 1 A ARG 213 ? NH2 ? A ARG 224 NH2 
86  1 Y 1 A GLN 214 ? CG  ? A GLN 225 CG  
87  1 Y 1 A GLN 214 ? CD  ? A GLN 225 CD  
88  1 Y 1 A GLN 214 ? OE1 ? A GLN 225 OE1 
89  1 Y 1 A GLN 214 ? NE2 ? A GLN 225 NE2 
90  1 Y 1 A SER 216 ? OG  ? A SER 227 OG  
91  1 Y 1 A ASP 218 ? CG  ? A ASP 229 CG  
92  1 Y 1 A ASP 218 ? OD1 ? A ASP 229 OD1 
93  1 Y 1 A ASP 218 ? OD2 ? A ASP 229 OD2 
94  1 Y 1 A THR 222 ? OG1 ? A THR 233 OG1 
95  1 Y 1 A THR 222 ? CG2 ? A THR 233 CG2 
96  1 Y 1 A SER 224 ? OG  ? A SER 235 OG  
97  1 Y 1 A THR 227 ? OG1 ? A THR 238 OG1 
98  1 Y 1 A THR 227 ? CG2 ? A THR 238 CG2 
99  1 Y 1 A TRP 228 ? CG  ? A TRP 239 CG  
100 1 Y 1 A TRP 228 ? CD1 ? A TRP 239 CD1 
101 1 Y 1 A TRP 228 ? CD2 ? A TRP 239 CD2 
102 1 Y 1 A TRP 228 ? NE1 ? A TRP 239 NE1 
103 1 Y 1 A TRP 228 ? CE2 ? A TRP 239 CE2 
104 1 Y 1 A TRP 228 ? CE3 ? A TRP 239 CE3 
105 1 Y 1 A TRP 228 ? CZ2 ? A TRP 239 CZ2 
106 1 Y 1 A TRP 228 ? CZ3 ? A TRP 239 CZ3 
107 1 Y 1 A TRP 228 ? CH2 ? A TRP 239 CH2 
108 1 Y 1 A GLU 231 ? CG  ? A GLU 242 CG  
109 1 Y 1 A GLU 231 ? CD  ? A GLU 242 CD  
110 1 Y 1 A GLU 231 ? OE1 ? A GLU 242 OE1 
111 1 Y 1 A GLU 231 ? OE2 ? A GLU 242 OE2 
112 1 Y 1 A MET 245 ? CG  ? A MET 256 CG  
113 1 Y 1 A MET 245 ? SD  ? A MET 256 SD  
114 1 Y 1 A MET 245 ? CE  ? A MET 256 CE  
115 1 Y 1 A ARG 260 ? CG  ? A ARG 271 CG  
116 1 Y 1 A ARG 260 ? CD  ? A ARG 271 CD  
117 1 Y 1 A ARG 260 ? NE  ? A ARG 271 NE  
118 1 Y 1 A ARG 260 ? CZ  ? A ARG 271 CZ  
119 1 Y 1 A ARG 260 ? NH1 ? A ARG 271 NH1 
120 1 Y 1 A ARG 260 ? NH2 ? A ARG 271 NH2 
121 1 Y 1 A LYS 262 ? CG  ? A LYS 273 CG  
122 1 Y 1 A LYS 262 ? CD  ? A LYS 273 CD  
123 1 Y 1 A LYS 262 ? CE  ? A LYS 273 CE  
124 1 Y 1 A LYS 262 ? NZ  ? A LYS 273 NZ  
125 1 Y 1 A SER 263 ? OG  ? A SER 274 OG  
126 1 Y 1 A SER 268 ? OG  ? A SER 279 OG  
127 1 Y 1 A SER 270 ? OG  ? A SER 281 OG  
128 1 Y 1 A GLU 272 ? CG  ? A GLU 283 CG  
129 1 Y 1 A GLU 272 ? CD  ? A GLU 283 CD  
130 1 Y 1 A GLU 272 ? OE1 ? A GLU 283 OE1 
131 1 Y 1 A GLU 272 ? OE2 ? A GLU 283 OE2 
132 1 Y 1 A LYS 273 ? CG  ? A LYS 284 CG  
133 1 Y 1 A LYS 273 ? CD  ? A LYS 284 CD  
134 1 Y 1 A LYS 273 ? CE  ? A LYS 284 CE  
135 1 Y 1 A LYS 273 ? NZ  ? A LYS 284 NZ  
136 1 Y 1 A ARG 275 ? CG  ? A ARG 286 CG  
137 1 Y 1 A ARG 275 ? CD  ? A ARG 286 CD  
138 1 Y 1 A ARG 275 ? NE  ? A ARG 286 NE  
139 1 Y 1 A ARG 275 ? CZ  ? A ARG 286 CZ  
140 1 Y 1 A ARG 275 ? NH1 ? A ARG 286 NH1 
141 1 Y 1 A ARG 275 ? NH2 ? A ARG 286 NH2 
142 1 Y 1 A ARG 279 ? CG  ? A ARG 290 CG  
143 1 Y 1 A ARG 279 ? CD  ? A ARG 290 CD  
144 1 Y 1 A ARG 279 ? NE  ? A ARG 290 NE  
145 1 Y 1 A ARG 279 ? CZ  ? A ARG 290 CZ  
146 1 Y 1 A ARG 279 ? NH1 ? A ARG 290 NH1 
147 1 Y 1 A ARG 279 ? NH2 ? A ARG 290 NH2 
148 1 Y 1 A TYR 301 ? CG  ? A TYR 312 CG  
149 1 Y 1 A TYR 301 ? CD1 ? A TYR 312 CD1 
150 1 Y 1 A TYR 301 ? CD2 ? A TYR 312 CD2 
151 1 Y 1 A TYR 301 ? CE1 ? A TYR 312 CE1 
152 1 Y 1 A TYR 301 ? CE2 ? A TYR 312 CE2 
153 1 Y 1 A TYR 301 ? CZ  ? A TYR 312 CZ  
154 1 Y 1 A TYR 301 ? OH  ? A TYR 312 OH  
155 1 Y 1 A THR 309 ? OG1 ? A THR 320 OG1 
156 1 Y 1 A THR 309 ? CG2 ? A THR 320 CG2 
157 1 Y 1 A GLU 312 ? CG  ? A GLU 323 CG  
158 1 Y 1 A GLU 312 ? CD  ? A GLU 323 CD  
159 1 Y 1 A GLU 312 ? OE1 ? A GLU 323 OE1 
160 1 Y 1 A GLU 312 ? OE2 ? A GLU 323 OE2 
161 1 Y 1 A THR 313 ? OG1 ? A THR 324 OG1 
162 1 Y 1 A THR 313 ? CG2 ? A THR 324 CG2 
163 1 Y 1 A THR 314 ? OG1 ? A THR 325 OG1 
164 1 Y 1 A THR 314 ? CG2 ? A THR 325 CG2 
165 1 Y 1 A THR 317 ? OG1 ? A THR 328 OG1 
166 1 Y 1 A THR 317 ? CG2 ? A THR 328 CG2 
167 1 Y 1 A LEU 337 ? CG  ? A LEU 348 CG  
168 1 Y 1 A LEU 337 ? CD1 ? A LEU 348 CD1 
169 1 Y 1 A LEU 337 ? CD2 ? A LEU 348 CD2 
170 1 Y 1 A GLU 343 ? CG  ? A GLU 354 CG  
171 1 Y 1 A GLU 343 ? CD  ? A GLU 354 CD  
172 1 Y 1 A GLU 343 ? OE1 ? A GLU 354 OE1 
173 1 Y 1 A GLU 343 ? OE2 ? A GLU 354 OE2 
174 1 Y 1 A LYS 346 ? CG  ? A LYS 357 CG  
175 1 Y 1 A LYS 346 ? CD  ? A LYS 357 CD  
176 1 Y 1 A LYS 346 ? CE  ? A LYS 357 CE  
177 1 Y 1 A LYS 346 ? NZ  ? A LYS 357 NZ  
178 1 Y 1 A ARG 347 ? CG  ? A ARG 358 CG  
179 1 Y 1 A ARG 347 ? CD  ? A ARG 358 CD  
180 1 Y 1 A ARG 347 ? NE  ? A ARG 358 NE  
181 1 Y 1 A ARG 347 ? CZ  ? A ARG 358 CZ  
182 1 Y 1 A ARG 347 ? NH1 ? A ARG 358 NH1 
183 1 Y 1 A ARG 347 ? NH2 ? A ARG 358 NH2 
184 1 Y 1 A ARG 350 ? CG  ? A ARG 361 CG  
185 1 Y 1 A ARG 350 ? CD  ? A ARG 361 CD  
186 1 Y 1 A ARG 350 ? NE  ? A ARG 361 NE  
187 1 Y 1 A ARG 350 ? CZ  ? A ARG 361 CZ  
188 1 Y 1 A ARG 350 ? NH1 ? A ARG 361 NH1 
189 1 Y 1 A ARG 350 ? NH2 ? A ARG 361 NH2 
190 1 Y 1 A GLU 351 ? CG  ? A GLU 362 CG  
191 1 Y 1 A GLU 351 ? CD  ? A GLU 362 CD  
192 1 Y 1 A GLU 351 ? OE1 ? A GLU 362 OE1 
193 1 Y 1 A GLU 351 ? OE2 ? A GLU 362 OE2 
194 1 Y 1 A CYS 353 ? SG  ? A CYS 364 SG  
195 1 Y 1 A ILE 354 ? CG1 ? A ILE 365 CG1 
196 1 Y 1 A ILE 354 ? CG2 ? A ILE 365 CG2 
197 1 Y 1 A ILE 354 ? CD1 ? A ILE 365 CD1 
198 1 Y 1 C ARG 4   ? CG  ? B ARG 2   CG  
199 1 Y 1 C ARG 4   ? CD  ? B ARG 2   CD  
200 1 Y 1 C ARG 4   ? NE  ? B ARG 2   NE  
201 1 Y 1 C ARG 4   ? CZ  ? B ARG 2   CZ  
202 1 Y 1 C ARG 4   ? NH1 ? B ARG 2   NH1 
203 1 Y 1 C ARG 4   ? NH2 ? B ARG 2   NH2 
204 1 Y 1 C GLN 5   ? CG  ? B GLN 3   CG  
205 1 Y 1 C GLN 5   ? CD  ? B GLN 3   CD  
206 1 Y 1 C GLN 5   ? OE1 ? B GLN 3   OE1 
207 1 Y 1 C GLN 5   ? NE2 ? B GLN 3   NE2 
208 1 Y 1 C SER 9   ? OG  ? B SER 7   OG  
209 1 Y 1 C LEU 13  ? CG  ? B LEU 11  CG  
210 1 Y 1 C LEU 13  ? CD1 ? B LEU 11  CD1 
211 1 Y 1 C LEU 13  ? CD2 ? B LEU 11  CD2 
212 1 Y 1 C GLN 15  ? CG  ? B GLN 13  CG  
213 1 Y 1 C GLN 15  ? CD  ? B GLN 13  CD  
214 1 Y 1 C GLN 15  ? OE1 ? B GLN 13  OE1 
215 1 Y 1 C GLN 15  ? NE2 ? B GLN 13  NE2 
216 1 Y 1 C SER 19  ? OG  ? B SER 17  OG  
217 1 Y 1 C ARG 21  ? CG  ? B ARG 19  CG  
218 1 Y 1 C ARG 21  ? CD  ? B ARG 19  CD  
219 1 Y 1 C ARG 21  ? NE  ? B ARG 19  NE  
220 1 Y 1 C ARG 21  ? CZ  ? B ARG 19  CZ  
221 1 Y 1 C ARG 21  ? NH1 ? B ARG 19  NH1 
222 1 Y 1 C ARG 21  ? NH2 ? B ARG 19  NH2 
223 1 Y 1 C SER 23  ? OG  ? B SER 21  OG  
224 1 Y 1 C SER 27  ? OG  ? B SER 25  OG  
225 1 Y 1 C ARG 40  ? CG  ? B ARG 38  CG  
226 1 Y 1 C ARG 40  ? CD  ? B ARG 38  CD  
227 1 Y 1 C ARG 40  ? NE  ? B ARG 38  NE  
228 1 Y 1 C ARG 40  ? CZ  ? B ARG 38  CZ  
229 1 Y 1 C ARG 40  ? NH1 ? B ARG 38  NH1 
230 1 Y 1 C ARG 40  ? NH2 ? B ARG 38  NH2 
231 1 Y 1 C LYS 45  ? CG  ? B LYS 43  CG  
232 1 Y 1 C LYS 45  ? CD  ? B LYS 43  CD  
233 1 Y 1 C LYS 45  ? CE  ? B LYS 43  CE  
234 1 Y 1 C LYS 45  ? NZ  ? B LYS 43  NZ  
235 1 Y 1 C SER 52  ? OG  ? B SER 50  OG  
236 1 Y 1 C SER 55  ? OG  ? B SER 53  OG  
237 1 Y 1 C SER 58  ? OG  ? B SER 56  OG  
238 1 Y 1 C LYS 60  ? CG  ? B LYS 58  CG  
239 1 Y 1 C LYS 60  ? CD  ? B LYS 58  CD  
240 1 Y 1 C LYS 60  ? CE  ? B LYS 58  CE  
241 1 Y 1 C LYS 60  ? NZ  ? B LYS 58  NZ  
242 1 Y 1 C ASP 63  ? CG  ? B ASP 61  CG  
243 1 Y 1 C ASP 63  ? OD1 ? B ASP 61  OD1 
244 1 Y 1 C ASP 63  ? OD2 ? B ASP 61  OD2 
245 1 Y 1 C SER 64  ? OG  ? B SER 62  OG  
246 1 Y 1 C VAL 65  ? CG1 ? B VAL 63  CG1 
247 1 Y 1 C VAL 65  ? CG2 ? B VAL 63  CG2 
248 1 Y 1 C LYS 66  ? CG  ? B LYS 64  CG  
249 1 Y 1 C LYS 66  ? CD  ? B LYS 64  CD  
250 1 Y 1 C LYS 66  ? CE  ? B LYS 64  CE  
251 1 Y 1 C LYS 66  ? NZ  ? B LYS 64  NZ  
252 1 Y 1 C LYS 77  ? CG  ? B LYS 75  CG  
253 1 Y 1 C LYS 77  ? CD  ? B LYS 75  CD  
254 1 Y 1 C LYS 77  ? CE  ? B LYS 75  CE  
255 1 Y 1 C LYS 77  ? NZ  ? B LYS 75  NZ  
256 1 Y 1 C ASN 78  ? CG  ? B ASN 76  CG  
257 1 Y 1 C ASN 78  ? OD1 ? B ASN 76  OD1 
258 1 Y 1 C ASN 78  ? ND2 ? B ASN 76  ND2 
259 1 Y 1 C SER 86  ? OG  ? B SER 84  OG  
260 1 Y 1 C GLU 88  ? CG  ? B GLU 86  CG  
261 1 Y 1 C GLU 88  ? CD  ? B GLU 86  CD  
262 1 Y 1 C GLU 88  ? OE1 ? B GLU 86  OE1 
263 1 Y 1 C GLU 88  ? OE2 ? B GLU 86  OE2 
264 1 Y 1 C GLU 90  ? CG  ? B GLU 88  CG  
265 1 Y 1 C GLU 90  ? CD  ? B GLU 88  CD  
266 1 Y 1 C GLU 90  ? OE1 ? B GLU 88  OE1 
267 1 Y 1 C GLU 90  ? OE2 ? B GLU 88  OE2 
268 1 Y 1 C ASN 98  ? CG  ? B ASN 96  CG  
269 1 Y 1 C ASN 98  ? OD1 ? B ASN 96  OD1 
270 1 Y 1 C ASN 98  ? ND2 ? B ASN 96  ND2 
271 1 Y 1 C GLU 100 ? CG  ? B GLU 98  CG  
272 1 Y 1 C GLU 100 ? CD  ? B GLU 98  CD  
273 1 Y 1 C GLU 100 ? OE1 ? B GLU 98  OE1 
274 1 Y 1 C GLU 100 ? OE2 ? B GLU 98  OE2 
275 1 Y 1 C GLU 107 ? CG  ? B GLU 105 CG  
276 1 Y 1 C GLU 107 ? CD  ? B GLU 105 CD  
277 1 Y 1 C GLU 107 ? OE1 ? B GLU 105 OE1 
278 1 Y 1 C GLU 107 ? OE2 ? B GLU 105 OE2 
279 1 Y 1 C GLU 108 ? CG  ? B GLU 106 CG  
280 1 Y 1 C GLU 108 ? CD  ? B GLU 106 CD  
281 1 Y 1 C GLU 108 ? OE1 ? B GLU 106 OE1 
282 1 Y 1 C GLU 108 ? OE2 ? B GLU 106 OE2 
283 1 Y 1 C VAL 121 ? CG1 ? B VAL 119 CG1 
284 1 Y 1 C VAL 121 ? CG2 ? B VAL 119 CG2 
285 1 Y 1 C SER 122 ? OG  ? B SER 120 OG  
286 1 Y 1 C SER 123 ? OG  ? B SER 121 OG  
287 1 Y 1 H GLU 6   ? CG  ? C GLU 9   CG  
288 1 Y 1 H GLU 6   ? CD  ? C GLU 9   CD  
289 1 Y 1 H GLU 6   ? OE1 ? C GLU 9   OE1 
290 1 Y 1 H GLU 6   ? OE2 ? C GLU 9   OE2 
291 1 Y 1 H SER 17  ? OG  ? C SER 20  OG  
292 1 Y 1 H LEU 18  ? CG  ? C LEU 21  CG  
293 1 Y 1 H LEU 18  ? CD1 ? C LEU 21  CD1 
294 1 Y 1 H LEU 18  ? CD2 ? C LEU 21  CD2 
295 1 Y 1 H ARG 19  ? CG  ? C ARG 22  CG  
296 1 Y 1 H ARG 19  ? CD  ? C ARG 22  CD  
297 1 Y 1 H ARG 19  ? NE  ? C ARG 22  NE  
298 1 Y 1 H ARG 19  ? CZ  ? C ARG 22  CZ  
299 1 Y 1 H ARG 19  ? NH1 ? C ARG 22  NH1 
300 1 Y 1 H ARG 19  ? NH2 ? C ARG 22  NH2 
301 1 Y 1 H SER 21  ? OG  ? C SER 24  OG  
302 1 Y 1 H SER 25  ? OG  ? C SER 28  OG  
303 1 Y 1 H SER 30  ? OG  ? C SER 33  OG  
304 1 Y 1 H LYS 43  ? CG  ? C LYS 46  CG  
305 1 Y 1 H LYS 43  ? CD  ? C LYS 46  CD  
306 1 Y 1 H LYS 43  ? CE  ? C LYS 46  CE  
307 1 Y 1 H LYS 43  ? NZ  ? C LYS 46  NZ  
308 1 Y 1 H ILE 51  ? CG1 ? C ILE 54  CG1 
309 1 Y 1 H ILE 51  ? CG2 ? C ILE 54  CG2 
310 1 Y 1 H ILE 51  ? CD1 ? C ILE 54  CD1 
311 1 Y 1 H SER 58  ? OG  ? C SER 62  OG  
312 1 Y 1 H ASP 61  ? CG  ? C ASP 65  CG  
313 1 Y 1 H ASP 61  ? OD1 ? C ASP 65  OD1 
314 1 Y 1 H ASP 61  ? OD2 ? C ASP 65  OD2 
315 1 Y 1 H VAL 63  ? CG1 ? C VAL 67  CG1 
316 1 Y 1 H VAL 63  ? CG2 ? C VAL 67  CG2 
317 1 Y 1 H LYS 64  ? CG  ? C LYS 68  CG  
318 1 Y 1 H LYS 64  ? CD  ? C LYS 68  CD  
319 1 Y 1 H LYS 64  ? CE  ? C LYS 68  CE  
320 1 Y 1 H LYS 64  ? NZ  ? C LYS 68  NZ  
321 1 Y 1 H SER 70  ? OG  ? C SER 74  OG  
322 1 Y 1 H ASP 72  ? CG  ? C ASP 76  CG  
323 1 Y 1 H ASP 72  ? OD1 ? C ASP 76  OD1 
324 1 Y 1 H ASP 72  ? OD2 ? C ASP 76  OD2 
325 1 Y 1 H ASN 76  ? CG  ? C ASN 80  CG  
326 1 Y 1 H ASN 76  ? OD1 ? C ASN 80  OD1 
327 1 Y 1 H ASN 76  ? ND2 ? C ASN 80  ND2 
328 1 Y 1 H THR 77  ? OG1 ? C THR 81  OG1 
329 1 Y 1 H THR 77  ? CG2 ? C THR 81  CG2 
330 1 Y 1 H GLN 81  ? CG  ? C GLN 85  CG  
331 1 Y 1 H GLN 81  ? CD  ? C GLN 85  CD  
332 1 Y 1 H GLN 81  ? OE1 ? C GLN 85  OE1 
333 1 Y 1 H GLN 81  ? NE2 ? C GLN 85  NE2 
334 1 Y 1 H ASN 83  ? CG  ? C ASN 87  CG  
335 1 Y 1 H ASN 83  ? OD1 ? C ASN 87  OD1 
336 1 Y 1 H ASN 83  ? ND2 ? C ASN 87  ND2 
337 1 Y 1 H SER 84  ? OG  ? C SER 88  OG  
338 1 Y 1 H ARG 86  ? CG  ? C ARG 90  CG  
339 1 Y 1 H ARG 86  ? CD  ? C ARG 90  CD  
340 1 Y 1 H ARG 86  ? NE  ? C ARG 90  NE  
341 1 Y 1 H ARG 86  ? CZ  ? C ARG 90  CZ  
342 1 Y 1 H ARG 86  ? NH1 ? C ARG 90  NH1 
343 1 Y 1 H ARG 86  ? NH2 ? C ARG 90  NH2 
344 1 Y 1 H GLN 103 ? CG  ? C GLN 107 CG  
345 1 Y 1 H GLN 103 ? CD  ? C GLN 107 CD  
346 1 Y 1 H GLN 103 ? OE1 ? C GLN 107 OE1 
347 1 Y 1 H GLN 103 ? NE2 ? C GLN 107 NE2 
348 1 Y 1 H GLN 119 ? CG  ? C GLN 123 CG  
349 1 Y 1 H GLN 119 ? CD  ? C GLN 123 CD  
350 1 Y 1 H GLN 119 ? OE1 ? C GLN 123 OE1 
351 1 Y 1 H GLN 119 ? NE2 ? C GLN 123 NE2 
352 1 Y 1 H THR 121 ? OG1 ? C THR 125 OG1 
353 1 Y 1 H THR 121 ? CG2 ? C THR 125 CG2 
354 1 Y 1 H SER 126 ? OG  ? C SER 130 OG  
355 1 Y 1 H SER 127 ? OG  ? C SER 131 OG  
356 1 Y 1 H SER 129 ? OG  ? C SER 133 OG  
357 1 Y 1 H LYS 131 ? CG  ? C LYS 135 CG  
358 1 Y 1 H LYS 131 ? CD  ? C LYS 135 CD  
359 1 Y 1 H LYS 131 ? CE  ? C LYS 135 CE  
360 1 Y 1 H LYS 131 ? NZ  ? C LYS 135 NZ  
361 1 Y 1 H SER 134 ? OG  ? C SER 138 OG  
362 1 Y 1 H SER 141 ? OG  ? C SER 145 OG  
363 1 Y 1 H THR 142 ? OG1 ? C THR 153 OG1 
364 1 Y 1 H THR 142 ? CG2 ? C THR 153 CG2 
365 1 Y 1 H ASP 151 ? CG  ? C ASP 162 CG  
366 1 Y 1 H ASP 151 ? OD1 ? C ASP 162 OD1 
367 1 Y 1 H ASP 151 ? OD2 ? C ASP 162 OD2 
368 1 Y 1 H THR 154 ? OG1 ? C THR 169 OG1 
369 1 Y 1 H THR 154 ? CG2 ? C THR 169 CG2 
370 1 Y 1 H SER 156 ? OG  ? C SER 171 OG  
371 1 Y 1 H TRP 157 ? CG  ? C TRP 172 CG  
372 1 Y 1 H TRP 157 ? CD1 ? C TRP 172 CD1 
373 1 Y 1 H TRP 157 ? CD2 ? C TRP 172 CD2 
374 1 Y 1 H TRP 157 ? NE1 ? C TRP 172 NE1 
375 1 Y 1 H TRP 157 ? CE2 ? C TRP 172 CE2 
376 1 Y 1 H TRP 157 ? CE3 ? C TRP 172 CE3 
377 1 Y 1 H TRP 157 ? CZ2 ? C TRP 172 CZ2 
378 1 Y 1 H TRP 157 ? CZ3 ? C TRP 172 CZ3 
379 1 Y 1 H TRP 157 ? CH2 ? C TRP 172 CH2 
380 1 Y 1 H GLN 171 ? CG  ? C GLN 189 CG  
381 1 Y 1 H GLN 171 ? CD  ? C GLN 189 CD  
382 1 Y 1 H GLN 171 ? OE1 ? C GLN 189 OE1 
383 1 Y 1 H GLN 171 ? NE2 ? C GLN 189 NE2 
384 1 Y 1 H SER 172 ? OG  ? C SER 190 OG  
385 1 Y 1 H SER 180 ? OG  ? C SER 198 OG  
386 1 Y 1 H VAL 182 ? CG1 ? C VAL 200 CG1 
387 1 Y 1 H VAL 182 ? CG2 ? C VAL 200 CG2 
388 1 Y 1 H LYS 201 ? CG  ? C LYS 219 CG  
389 1 Y 1 H LYS 201 ? CD  ? C LYS 219 CD  
390 1 Y 1 H LYS 201 ? CE  ? C LYS 219 CE  
391 1 Y 1 H LYS 201 ? NZ  ? C LYS 219 NZ  
392 1 Y 1 H SER 203 ? OG  ? C SER 221 OG  
393 1 Y 1 H ASN 204 ? CG  ? C ASN 222 CG  
394 1 Y 1 H ASN 204 ? OD1 ? C ASN 222 OD1 
395 1 Y 1 H ASN 204 ? ND2 ? C ASN 222 ND2 
396 1 Y 1 H LYS 206 ? CG  ? C LYS 224 CG  
397 1 Y 1 H LYS 206 ? CD  ? C LYS 224 CD  
398 1 Y 1 H LYS 206 ? CE  ? C LYS 224 CE  
399 1 Y 1 H LYS 206 ? NZ  ? C LYS 224 NZ  
400 1 Y 1 H LYS 210 ? CG  ? C LYS 228 CG  
401 1 Y 1 H LYS 210 ? CD  ? C LYS 228 CD  
402 1 Y 1 H LYS 210 ? CE  ? C LYS 228 CE  
403 1 Y 1 H LYS 210 ? NZ  ? C LYS 228 NZ  
404 1 Y 1 H GLU 212 ? CG  ? C GLU 230 CG  
405 1 Y 1 H GLU 212 ? CD  ? C GLU 230 CD  
406 1 Y 1 H GLU 212 ? OE1 ? C GLU 230 OE1 
407 1 Y 1 H GLU 212 ? OE2 ? C GLU 230 OE2 
408 1 Y 1 L THR 5   ? OG1 ? D THR 6   OG1 
409 1 Y 1 L THR 5   ? CG2 ? D THR 6   CG2 
410 1 Y 1 L SER 9   ? OG  ? D SER 10  OG  
411 1 Y 1 L SER 12  ? OG  ? D SER 13  OG  
412 1 Y 1 L THR 20  ? OG1 ? D THR 21  OG1 
413 1 Y 1 L THR 20  ? CG2 ? D THR 21  CG2 
414 1 Y 1 L ARG 24  ? CG  ? D ARG 25  CG  
415 1 Y 1 L ARG 24  ? CD  ? D ARG 25  CD  
416 1 Y 1 L ARG 24  ? NE  ? D ARG 25  NE  
417 1 Y 1 L ARG 24  ? CZ  ? D ARG 25  CZ  
418 1 Y 1 L ARG 24  ? NH1 ? D ARG 25  NH1 
419 1 Y 1 L ARG 24  ? NH2 ? D ARG 25  NH2 
420 1 Y 1 L SER 30  ? OG  ? D SER 31  OG  
421 1 Y 1 L LYS 39  ? CG  ? D LYS 40  CG  
422 1 Y 1 L LYS 39  ? CD  ? D LYS 40  CD  
423 1 Y 1 L LYS 39  ? CE  ? D LYS 40  CE  
424 1 Y 1 L LYS 39  ? NZ  ? D LYS 40  NZ  
425 1 Y 1 L SER 60  ? OG  ? D SER 61  OG  
426 1 Y 1 L SER 63  ? OG  ? D SER 64  OG  
427 1 Y 1 L SER 65  ? OG  ? D SER 66  OG  
428 1 Y 1 L ARG 66  ? CG  ? D ARG 67  CG  
429 1 Y 1 L ARG 66  ? CD  ? D ARG 67  CD  
430 1 Y 1 L ARG 66  ? NE  ? D ARG 67  NE  
431 1 Y 1 L ARG 66  ? CZ  ? D ARG 67  CZ  
432 1 Y 1 L ARG 66  ? NH1 ? D ARG 67  NH1 
433 1 Y 1 L ARG 66  ? NH2 ? D ARG 67  NH2 
434 1 Y 1 L THR 69  ? OG1 ? D THR 70  OG1 
435 1 Y 1 L THR 69  ? CG2 ? D THR 70  CG2 
436 1 Y 1 L ASP 70  ? CG  ? D ASP 71  CG  
437 1 Y 1 L ASP 70  ? OD1 ? D ASP 71  OD1 
438 1 Y 1 L ASP 70  ? OD2 ? D ASP 71  OD2 
439 1 Y 1 L THR 72  ? OG1 ? D THR 73  OG1 
440 1 Y 1 L THR 72  ? CG2 ? D THR 73  CG2 
441 1 Y 1 L SER 76  ? OG  ? D SER 77  OG  
442 1 Y 1 L GLN 79  ? CG  ? D GLN 80  CG  
443 1 Y 1 L GLN 79  ? CD  ? D GLN 80  CD  
444 1 Y 1 L GLN 79  ? OE1 ? D GLN 80  OE1 
445 1 Y 1 L GLN 79  ? NE2 ? D GLN 80  NE2 
446 1 Y 1 L GLU 81  ? CG  ? D GLU 82  CG  
447 1 Y 1 L GLU 81  ? CD  ? D GLU 82  CD  
448 1 Y 1 L GLU 81  ? OE1 ? D GLU 82  OE1 
449 1 Y 1 L GLU 81  ? OE2 ? D GLU 82  OE2 
450 1 Y 1 L SER 91  ? OG  ? D SER 92  OG  
451 1 Y 1 L SER 92  ? OG  ? D SER 93  OG  
452 1 Y 1 L SER 93  ? OG  ? D SER 94  OG  
453 1 Y 1 L SER 94  ? OG  ? D SER 95  OG  
454 1 Y 1 L LEU 95  ? CG  ? D LEU 96  CG  
455 1 Y 1 L LEU 95  ? CD1 ? D LEU 96  CD1 
456 1 Y 1 L LEU 95  ? CD2 ? D LEU 96  CD2 
457 1 Y 1 L ARG 108 ? CG  ? D ARG 109 CG  
458 1 Y 1 L ARG 108 ? CD  ? D ARG 109 CD  
459 1 Y 1 L ARG 108 ? NE  ? D ARG 109 NE  
460 1 Y 1 L ARG 108 ? CZ  ? D ARG 109 CZ  
461 1 Y 1 L ARG 108 ? NH1 ? D ARG 109 NH1 
462 1 Y 1 L ARG 108 ? NH2 ? D ARG 109 NH2 
463 1 Y 1 L THR 109 ? OG1 ? D THR 110 OG1 
464 1 Y 1 L THR 109 ? CG2 ? D THR 110 CG2 
465 1 Y 1 L SER 114 ? OG  ? D SER 115 OG  
466 1 Y 1 L ASP 122 ? CG  ? D ASP 123 CG  
467 1 Y 1 L ASP 122 ? OD1 ? D ASP 123 OD1 
468 1 Y 1 L ASP 122 ? OD2 ? D ASP 123 OD2 
469 1 Y 1 L SER 123 ? OG  ? D SER 124 OG  
470 1 Y 1 L LYS 126 ? CG  ? D LYS 127 CG  
471 1 Y 1 L LYS 126 ? CD  ? D LYS 127 CD  
472 1 Y 1 L LYS 126 ? CE  ? D LYS 127 CE  
473 1 Y 1 L LYS 126 ? NZ  ? D LYS 127 NZ  
474 1 Y 1 L SER 127 ? OG  ? D SER 128 OG  
475 1 Y 1 L GLN 147 ? CG  ? D GLN 148 CG  
476 1 Y 1 L GLN 147 ? CD  ? D GLN 148 CD  
477 1 Y 1 L GLN 147 ? OE1 ? D GLN 148 OE1 
478 1 Y 1 L GLN 147 ? NE2 ? D GLN 148 NE2 
479 1 Y 1 L LYS 149 ? CG  ? D LYS 150 CG  
480 1 Y 1 L LYS 149 ? CD  ? D LYS 150 CD  
481 1 Y 1 L LYS 149 ? CE  ? D LYS 150 CE  
482 1 Y 1 L LYS 149 ? NZ  ? D LYS 150 NZ  
483 1 Y 1 L ASN 152 ? CG  ? D ASN 153 CG  
484 1 Y 1 L ASN 152 ? OD1 ? D ASN 153 OD1 
485 1 Y 1 L ASN 152 ? ND2 ? D ASN 153 ND2 
486 1 Y 1 L LEU 154 ? CG  ? D LEU 155 CG  
487 1 Y 1 L LEU 154 ? CD1 ? D LEU 155 CD1 
488 1 Y 1 L LEU 154 ? CD2 ? D LEU 155 CD2 
489 1 Y 1 L SER 156 ? OG  ? D SER 157 OG  
490 1 Y 1 L SER 159 ? OG  ? D SER 160 OG  
491 1 Y 1 L GLU 165 ? CG  ? D GLU 166 CG  
492 1 Y 1 L GLU 165 ? CD  ? D GLU 166 CD  
493 1 Y 1 L GLU 165 ? OE1 ? D GLU 166 OE1 
494 1 Y 1 L GLU 165 ? OE2 ? D GLU 166 OE2 
495 1 Y 1 L SER 168 ? OG  ? D SER 169 OG  
496 1 Y 1 L LYS 169 ? CG  ? D LYS 170 CG  
497 1 Y 1 L LYS 169 ? CD  ? D LYS 170 CD  
498 1 Y 1 L LYS 169 ? CE  ? D LYS 170 CE  
499 1 Y 1 L LYS 169 ? NZ  ? D LYS 170 NZ  
500 1 Y 1 L ASP 170 ? CG  ? D ASP 171 CG  
501 1 Y 1 L ASP 170 ? OD1 ? D ASP 171 OD1 
502 1 Y 1 L ASP 170 ? OD2 ? D ASP 171 OD2 
503 1 Y 1 L SER 182 ? OG  ? D SER 183 OG  
504 1 Y 1 L LYS 190 ? CG  ? D LYS 191 CG  
505 1 Y 1 L LYS 190 ? CD  ? D LYS 191 CD  
506 1 Y 1 L LYS 190 ? CE  ? D LYS 191 CE  
507 1 Y 1 L LYS 190 ? NZ  ? D LYS 191 NZ  
508 1 Y 1 L THR 197 ? OG1 ? D THR 198 OG1 
509 1 Y 1 L THR 197 ? CG2 ? D THR 198 CG2 
510 1 Y 1 L SER 202 ? OG  ? D SER 203 OG  
511 1 Y 1 L SER 203 ? OG  ? D SER 204 OG  
512 1 Y 1 L ASN 210 ? CG  ? D ASN 211 CG  
513 1 Y 1 L ASN 210 ? OD1 ? D ASN 211 OD1 
514 1 Y 1 L ASN 210 ? ND2 ? D ASN 211 ND2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MQI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MQI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MQI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9MQI 
_struct.title                        'Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound #020_E1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MQI 
_struct_keywords.text            
'G-protein coupled receptor, Mu-opioid, isoquinuclidine, antagonist, nanobodies, fabs, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP OPRM_HUMAN P35372 ? 1 
;MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV
CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTL
CTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSW
HFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP

;
1 
2 PDB 9MQI       9MQI   ? 2 ? 1 
3 PDB 9MQI       9MQI   ? 3 ? 1 
4 PDB 9MQI       9MQI   ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9MQI A 12 ? 411 ? P35372 1  ? 400 ? 1  400 
2 2 9MQI C 1  ? 131 ? 9MQI   3  ? 133 ? 3  133 
3 3 9MQI H 1  ? 239 ? 9MQI   -2 ? 221 ? -2 221 
4 4 9MQI L 1  ? 215 ? 9MQI   0  ? 214 ? 0  214 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9MQI ASP A 1   ? UNP P35372 ?   ?   'expression tag' -10 1  
1 9MQI TYR A 2   ? UNP P35372 ?   ?   'expression tag' -9  2  
1 9MQI LYS A 3   ? UNP P35372 ?   ?   'expression tag' -8  3  
1 9MQI ASP A 4   ? UNP P35372 ?   ?   'expression tag' -7  4  
1 9MQI ASP A 5   ? UNP P35372 ?   ?   'expression tag' -6  5  
1 9MQI ASP A 6   ? UNP P35372 ?   ?   'expression tag' -5  6  
1 9MQI ASP A 7   ? UNP P35372 ?   ?   'expression tag' -4  7  
1 9MQI ALA A 8   ? UNP P35372 ?   ?   'expression tag' -3  8  
1 9MQI SER A 9   ? UNP P35372 ?   ?   'expression tag' -2  9  
1 9MQI ILE A 10  ? UNP P35372 ?   ?   'expression tag' -1  10 
1 9MQI ASP A 11  ? UNP P35372 ?   ?   'expression tag' 0   11 
1 9MQI LEU A 277 ? UNP P35372 MET 266 conflict         266 12 
1 9MQI ARG A 282 ? UNP P35372 LYS 271 conflict         271 13 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 78  ? TYR A 109 ? MET A 67  TYR A 98  1 ? 32 
HELX_P HELX_P2  AA2 THR A 110 ? LYS A 113 ? THR A 99  LYS A 102 5 ? 4  
HELX_P HELX_P3  AA3 THR A 114 ? THR A 133 ? THR A 103 THR A 122 1 ? 20 
HELX_P HELX_P4  AA4 THR A 133 ? GLY A 144 ? THR A 122 GLY A 133 1 ? 12 
HELX_P HELX_P5  AA5 GLY A 149 ? HIS A 184 ? GLY A 138 HIS A 173 1 ? 36 
HELX_P HELX_P6  AA6 HIS A 184 ? ARG A 192 ? HIS A 173 ARG A 181 1 ? 9  
HELX_P HELX_P7  AA7 THR A 193 ? MET A 218 ? THR A 182 MET A 207 1 ? 26 
HELX_P HELX_P8  AA8 SER A 235 ? SER A 235 ? SER A 224 SER A 224 1 ? 1  
HELX_P HELX_P9  AA9 TRP A 239 ? ALA A 253 ? TRP A 228 ALA A 242 1 ? 15 
HELX_P HELX_P10 AB1 PHE A 254 ? VAL A 275 ? PHE A 243 VAL A 264 1 ? 22 
HELX_P HELX_P11 AB2 SER A 281 ? VAL A 319 ? SER A 270 VAL A 308 1 ? 39 
HELX_P HELX_P12 AB3 THR A 324 ? LEU A 352 ? THR A 313 LEU A 341 1 ? 29 
HELX_P HELX_P13 AB4 ASP A 353 ? PHE A 363 ? ASP A 342 PHE A 352 1 ? 11 
HELX_P HELX_P14 AB5 GLU B 86  ? THR B 90  ? GLU C 88  THR C 92  5 ? 5  
HELX_P HELX_P15 AB6 TYR C 105 ? ALA C 110 ? TYR H 101 ALA H 106 1 ? 6  
HELX_P HELX_P16 AB7 SER D 122 ? GLY D 129 ? SER L 121 GLY L 128 1 ? 8  
HELX_P HELX_P17 AB8 LYS D 184 ? HIS D 190 ? LYS L 183 HIS L 189 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 153 SG ? ? ? 1_555 A CYS 230 SG ? ? A CYS 142 A CYS 219 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ? ? B CYS 22  SG ? ? ? 1_555 B CYS 95  SG ? ? C CYS 24  C CYS 97  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf3 disulf ? ? C CYS 25  SG ? ? ? 1_555 C CYS 99  SG ? ? H CYS 22  H CYS 95  1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf4 disulf ? ? C CYS 158 SG ? ? ? 1_555 C CYS 214 SG ? ? H CYS 147 H CYS 196 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf5 disulf ? ? D CYS 24  SG ? ? ? 1_555 D CYS 89  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf6 disulf ? ? D CYS 135 SG ? ? ? 1_555 D CYS 195 SG ? ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 153 ? CYS A 230 ? CYS A 142 ? 1_555 CYS A 219 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 22  ? CYS B 95  ? CYS C 24  ? 1_555 CYS C 97  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS C 25  ? CYS C 99  ? CYS H 22  ? 1_555 CYS H 95  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS C 158 ? CYS C 214 ? CYS H 147 ? 1_555 CYS H 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS D 24  ? CYS D 89  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS D 135 ? CYS D 195 ? CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           141 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            140 
_struct_mon_prot_cis.auth_asym_id           L 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    142 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     141 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    L 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.13 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 5 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
AB2 ? 2 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 219 ? TYR A 223 ? ALA A 208 TYR A 212 
AA1 2 ILE A 228 ? LEU A 232 ? ILE A 217 LEU A 221 
AA2 1 LEU B 4   ? SER B 7   ? LEU C 6   SER C 9   
AA2 2 LEU B 18  ? ALA B 24  ? LEU C 20  ALA C 26  
AA2 3 THR B 77  ? MET B 82  ? THR C 79  MET C 84  
AA2 4 PHE B 67  ? ASP B 72  ? PHE C 69  ASP C 74  
AA3 1 LEU B 11  ? VAL B 12  ? LEU C 13  VAL C 14  
AA3 2 THR B 115 ? VAL B 119 ? THR C 117 VAL C 121 
AA3 3 ALA B 91  ? ARG B 100 ? ALA C 93  ARG C 102 
AA3 4 LEU B 31  ? GLN B 39  ? LEU C 33  GLN C 41  
AA3 5 GLU B 46  ? ILE B 51  ? GLU C 48  ILE C 53  
AA3 6 THR B 57  ? TYR B 59  ? THR C 59  TYR C 61  
AA4 1 LEU B 11  ? VAL B 12  ? LEU C 13  VAL C 14  
AA4 2 THR B 115 ? VAL B 119 ? THR C 117 VAL C 121 
AA4 3 ALA B 91  ? ARG B 100 ? ALA C 93  ARG C 102 
AA4 4 LEU B 107 ? TRP B 111 ? LEU C 109 TRP C 113 
AA5 1 GLN C 6   ? SER C 10  ? GLN H 3   SER H 7   
AA5 2 LEU C 21  ? SER C 28  ? LEU H 18  SER H 25  
AA5 3 THR C 81  ? MET C 86  ? THR H 77  MET H 82  
AA5 4 PHE C 71  ? ALA C 75  ? PHE H 67  ALA H 71  
AA6 1 LEU C 14  ? VAL C 15  ? LEU H 11  VAL H 12  
AA6 2 THR C 125 ? VAL C 129 ? THR H 121 VAL H 125 
AA6 3 ALA C 95  ? TYR C 103 ? ALA H 91  TYR H 99  
AA6 4 TYR C 35  ? GLN C 42  ? TYR H 32  GLN H 39  
AA6 5 LEU C 48  ? TYR C 53  ? LEU H 45  TYR H 50  
AA7 1 SER C 138 ? LEU C 142 ? SER H 134 LEU H 138 
AA7 2 LEU C 156 ? LYS C 161 ? LEU H 145 LYS H 150 
AA7 3 LEU C 196 ? VAL C 200 ? LEU H 178 VAL H 182 
AA7 4 HIS C 182 ? THR C 183 ? HIS H 164 THR H 165 
AA8 1 THR C 169 ? SER C 171 ? THR H 154 SER H 156 
AA8 2 ASN C 215 ? HIS C 218 ? ASN H 197 HIS H 200 
AA8 3 THR C 223 ? VAL C 225 ? THR H 205 VAL H 207 
AA9 1 SER D 11  ? SER D 13  ? SER L 10  SER L 12  
AA9 2 THR D 103 ? GLU D 106 ? THR L 102 GLU L 105 
AA9 3 THR D 86  ? GLN D 91  ? THR L 85  GLN L 90  
AA9 4 VAL D 34  ? GLN D 39  ? VAL L 33  GLN L 38  
AA9 5 LYS D 46  ? TYR D 50  ? LYS L 45  TYR L 49  
AA9 6 SER D 54  ? LEU D 55  ? SER L 53  LEU L 54  
AB1 1 SER D 11  ? SER D 13  ? SER L 10  SER L 12  
AB1 2 THR D 103 ? GLU D 106 ? THR L 102 GLU L 105 
AB1 3 THR D 86  ? GLN D 91  ? THR L 85  GLN L 90  
AB1 4 THR D 98  ? PHE D 99  ? THR L 97  PHE L 98  
AB2 1 PHE D 63  ? SER D 66  ? PHE L 62  SER L 65  
AB2 2 THR D 73  ? ILE D 76  ? THR L 72  ILE L 75  
AB3 1 SER D 115 ? PHE D 119 ? SER L 114 PHE L 118 
AB3 2 THR D 130 ? PHE D 140 ? THR L 129 PHE L 139 
AB3 3 TYR D 174 ? SER D 183 ? TYR L 173 SER L 182 
AB3 4 SER D 160 ? VAL D 164 ? SER L 159 VAL L 163 
AB4 1 ALA D 154 ? GLN D 156 ? ALA L 153 GLN L 155 
AB4 2 LYS D 146 ? VAL D 151 ? LYS L 145 VAL L 150 
AB4 3 VAL D 192 ? THR D 198 ? VAL L 191 THR L 197 
AB4 4 VAL D 206 ? ASN D 211 ? VAL L 205 ASN L 210 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LYS A 222 ? N LYS A 211 O ASP A 229 ? O ASP A 218 
AA2 1 2 N VAL B 5   ? N VAL C 7   O ALA B 23  ? O ALA C 25  
AA2 2 3 N LEU B 18  ? N LEU C 20  O MET B 82  ? O MET C 84  
AA2 3 4 O GLN B 81  ? O GLN C 83  N THR B 68  ? N THR C 70  
AA3 1 2 N VAL B 12  ? N VAL C 14  O THR B 118 ? O THR C 120 
AA3 2 3 O VAL B 117 ? O VAL C 119 N ALA B 91  ? N ALA C 93  
AA3 3 4 O TYR B 94  ? O TYR C 96  N PHE B 37  ? N PHE C 39  
AA3 4 5 N ARG B 38  ? N ARG C 40  O GLU B 46  ? O GLU C 48  
AA3 5 6 N SER B 50  ? N SER C 52  O LYS B 58  ? O LYS C 60  
AA4 1 2 N VAL B 12  ? N VAL C 14  O THR B 118 ? O THR C 120 
AA4 2 3 O VAL B 117 ? O VAL C 119 N ALA B 91  ? N ALA C 93  
AA4 3 4 N TYR B 99  ? N TYR C 101 O LEU B 108 ? O LEU C 110 
AA5 1 2 N GLN C 6   ? N GLN H 3   O SER C 28  ? O SER H 25  
AA5 2 3 N LEU C 23  ? N LEU H 20  O LEU C 84  ? O LEU H 80  
AA5 3 4 O GLN C 85  ? O GLN H 81  N THR C 72  ? N THR H 68  
AA6 1 2 N VAL C 15  ? N VAL H 12  O THR C 128 ? O THR H 124 
AA6 2 3 O VAL C 127 ? O VAL H 123 N ALA C 95  ? N ALA H 91  
AA6 3 4 O TYR C 98  ? O TYR H 94  N VAL C 40  ? N VAL H 37  
AA6 4 5 N ARG C 41  ? N ARG H 38  O GLU C 49  ? O GLU H 46  
AA7 1 2 N LEU C 142 ? N LEU H 138 O GLY C 157 ? O GLY H 146 
AA7 2 3 N LEU C 156 ? N LEU H 145 O VAL C 200 ? O VAL H 182 
AA7 3 4 O VAL C 199 ? O VAL H 181 N HIS C 182 ? N HIS H 164 
AA8 1 2 N THR C 169 ? N THR H 154 O ASN C 217 ? O ASN H 199 
AA8 2 3 N HIS C 218 ? N HIS H 200 O THR C 223 ? O THR H 205 
AA9 1 2 N LEU D 12  ? N LEU L 11  O LYS D 104 ? O LYS L 103 
AA9 2 3 O THR D 103 ? O THR L 102 N TYR D 87  ? N TYR L 86  
AA9 3 4 O GLN D 90  ? O GLN L 89  N ALA D 35  ? N ALA L 34  
AA9 4 5 N GLN D 38  ? N GLN L 37  O LYS D 46  ? O LYS L 45  
AA9 5 6 N TYR D 50  ? N TYR L 49  O SER D 54  ? O SER L 53  
AB1 1 2 N LEU D 12  ? N LEU L 11  O LYS D 104 ? O LYS L 103 
AB1 2 3 O THR D 103 ? O THR L 102 N TYR D 87  ? N TYR L 86  
AB1 3 4 N GLN D 91  ? N GLN L 90  O THR D 98  ? O THR L 97  
AB2 1 2 N SER D 64  ? N SER L 63  O THR D 75  ? O THR L 74  
AB3 1 2 N PHE D 117 ? N PHE L 116 O LEU D 136 ? O LEU L 135 
AB3 2 3 N LEU D 137 ? N LEU L 136 O LEU D 176 ? O LEU L 175 
AB3 3 4 O THR D 179 ? O THR L 178 N GLN D 161 ? N GLN L 160 
AB4 1 2 O ALA D 154 ? O ALA L 153 N VAL D 151 ? N VAL L 150 
AB4 2 3 N GLN D 148 ? N GLN L 147 O GLU D 196 ? O GLU L 195 
AB4 3 4 N VAL D 197 ? N VAL L 196 O VAL D 206 ? O VAL L 205 
# 
_pdbx_entry_details.entry_id                   9MQI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE A 243 ? ? -120.22 -57.03  
2 1 SER C 122 ? ? -174.81 147.55  
3 1 TYR H 101 ? ? -91.95  52.95   
4 1 SER H 127 ? ? -92.53  53.18   
5 1 SER L 50  ? ? 56.59   19.18   
6 1 ALA L 51  ? ? 71.56   -10.01  
7 1 ALA L 84  ? ? -165.08 -168.20 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MQI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9MQI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'FOURIER SPACE' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               259816 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human Mu-Opioid Receptor' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        9MQI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2100 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             BASIC 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9MQI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9MQI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ASP -10 ? A ASP 1   
2   1 Y 1 A TYR -9  ? A TYR 2   
3   1 Y 1 A LYS -8  ? A LYS 3   
4   1 Y 1 A ASP -7  ? A ASP 4   
5   1 Y 1 A ASP -6  ? A ASP 5   
6   1 Y 1 A ASP -5  ? A ASP 6   
7   1 Y 1 A ASP -4  ? A ASP 7   
8   1 Y 1 A ALA -3  ? A ALA 8   
9   1 Y 1 A SER -2  ? A SER 9   
10  1 Y 1 A ILE -1  ? A ILE 10  
11  1 Y 1 A ASP 0   ? A ASP 11  
12  1 Y 1 A MET 1   ? A MET 12  
13  1 Y 1 A ASP 2   ? A ASP 13  
14  1 Y 1 A SER 3   ? A SER 14  
15  1 Y 1 A SER 4   ? A SER 15  
16  1 Y 1 A ALA 5   ? A ALA 16  
17  1 Y 1 A ALA 6   ? A ALA 17  
18  1 Y 1 A PRO 7   ? A PRO 18  
19  1 Y 1 A THR 8   ? A THR 19  
20  1 Y 1 A ASN 9   ? A ASN 20  
21  1 Y 1 A ALA 10  ? A ALA 21  
22  1 Y 1 A SER 11  ? A SER 22  
23  1 Y 1 A ASN 12  ? A ASN 23  
24  1 Y 1 A CYS 13  ? A CYS 24  
25  1 Y 1 A THR 14  ? A THR 25  
26  1 Y 1 A ASP 15  ? A ASP 26  
27  1 Y 1 A ALA 16  ? A ALA 27  
28  1 Y 1 A LEU 17  ? A LEU 28  
29  1 Y 1 A ALA 18  ? A ALA 29  
30  1 Y 1 A TYR 19  ? A TYR 30  
31  1 Y 1 A SER 20  ? A SER 31  
32  1 Y 1 A SER 21  ? A SER 32  
33  1 Y 1 A CYS 22  ? A CYS 33  
34  1 Y 1 A SER 23  ? A SER 34  
35  1 Y 1 A PRO 24  ? A PRO 35  
36  1 Y 1 A ALA 25  ? A ALA 36  
37  1 Y 1 A PRO 26  ? A PRO 37  
38  1 Y 1 A SER 27  ? A SER 38  
39  1 Y 1 A PRO 28  ? A PRO 39  
40  1 Y 1 A GLY 29  ? A GLY 40  
41  1 Y 1 A SER 30  ? A SER 41  
42  1 Y 1 A TRP 31  ? A TRP 42  
43  1 Y 1 A VAL 32  ? A VAL 43  
44  1 Y 1 A ASN 33  ? A ASN 44  
45  1 Y 1 A LEU 34  ? A LEU 45  
46  1 Y 1 A SER 35  ? A SER 46  
47  1 Y 1 A HIS 36  ? A HIS 47  
48  1 Y 1 A LEU 37  ? A LEU 48  
49  1 Y 1 A ASP 38  ? A ASP 49  
50  1 Y 1 A GLY 39  ? A GLY 50  
51  1 Y 1 A ASN 40  ? A ASN 51  
52  1 Y 1 A LEU 41  ? A LEU 52  
53  1 Y 1 A SER 42  ? A SER 53  
54  1 Y 1 A ASP 43  ? A ASP 54  
55  1 Y 1 A PRO 44  ? A PRO 55  
56  1 Y 1 A CYS 45  ? A CYS 56  
57  1 Y 1 A GLY 46  ? A GLY 57  
58  1 Y 1 A PRO 47  ? A PRO 58  
59  1 Y 1 A ASN 48  ? A ASN 59  
60  1 Y 1 A ARG 49  ? A ARG 60  
61  1 Y 1 A THR 50  ? A THR 61  
62  1 Y 1 A ASP 51  ? A ASP 62  
63  1 Y 1 A LEU 52  ? A LEU 63  
64  1 Y 1 A GLY 53  ? A GLY 64  
65  1 Y 1 A GLY 54  ? A GLY 65  
66  1 Y 1 A ARG 55  ? A ARG 66  
67  1 Y 1 A ASP 56  ? A ASP 67  
68  1 Y 1 A SER 57  ? A SER 68  
69  1 Y 1 A LEU 58  ? A LEU 69  
70  1 Y 1 A CYS 59  ? A CYS 70  
71  1 Y 1 A PRO 60  ? A PRO 71  
72  1 Y 1 A PRO 61  ? A PRO 72  
73  1 Y 1 A THR 62  ? A THR 73  
74  1 Y 1 A GLY 63  ? A GLY 74  
75  1 Y 1 A SER 64  ? A SER 75  
76  1 Y 1 A PRO 65  ? A PRO 76  
77  1 Y 1 A SER 66  ? A SER 77  
78  1 Y 1 A HIS 225 ? A HIS 236 
79  1 Y 1 A PRO 226 ? A PRO 237 
80  1 Y 1 A PRO 355 ? A PRO 366 
81  1 Y 1 A THR 356 ? A THR 367 
82  1 Y 1 A SER 357 ? A SER 368 
83  1 Y 1 A SER 358 ? A SER 369 
84  1 Y 1 A ASN 359 ? A ASN 370 
85  1 Y 1 A ILE 360 ? A ILE 371 
86  1 Y 1 A GLU 361 ? A GLU 372 
87  1 Y 1 A GLN 362 ? A GLN 373 
88  1 Y 1 A GLN 363 ? A GLN 374 
89  1 Y 1 A ASN 364 ? A ASN 375 
90  1 Y 1 A SER 365 ? A SER 376 
91  1 Y 1 A THR 366 ? A THR 377 
92  1 Y 1 A ARG 367 ? A ARG 378 
93  1 Y 1 A ILE 368 ? A ILE 379 
94  1 Y 1 A ARG 369 ? A ARG 380 
95  1 Y 1 A GLN 370 ? A GLN 381 
96  1 Y 1 A ASN 371 ? A ASN 382 
97  1 Y 1 A THR 372 ? A THR 383 
98  1 Y 1 A ARG 373 ? A ARG 384 
99  1 Y 1 A ASP 374 ? A ASP 385 
100 1 Y 1 A HIS 375 ? A HIS 386 
101 1 Y 1 A PRO 376 ? A PRO 387 
102 1 Y 1 A SER 377 ? A SER 388 
103 1 Y 1 A THR 378 ? A THR 389 
104 1 Y 1 A ALA 379 ? A ALA 390 
105 1 Y 1 A ASN 380 ? A ASN 391 
106 1 Y 1 A THR 381 ? A THR 392 
107 1 Y 1 A VAL 382 ? A VAL 393 
108 1 Y 1 A ASP 383 ? A ASP 394 
109 1 Y 1 A ARG 384 ? A ARG 395 
110 1 Y 1 A THR 385 ? A THR 396 
111 1 Y 1 A ASN 386 ? A ASN 397 
112 1 Y 1 A HIS 387 ? A HIS 398 
113 1 Y 1 A GLN 388 ? A GLN 399 
114 1 Y 1 A LEU 389 ? A LEU 400 
115 1 Y 1 A GLU 390 ? A GLU 401 
116 1 Y 1 A ASN 391 ? A ASN 402 
117 1 Y 1 A LEU 392 ? A LEU 403 
118 1 Y 1 A GLU 393 ? A GLU 404 
119 1 Y 1 A ALA 394 ? A ALA 405 
120 1 Y 1 A GLU 395 ? A GLU 406 
121 1 Y 1 A THR 396 ? A THR 407 
122 1 Y 1 A ALA 397 ? A ALA 408 
123 1 Y 1 A PRO 398 ? A PRO 409 
124 1 Y 1 A LEU 399 ? A LEU 410 
125 1 Y 1 A PRO 400 ? A PRO 411 
126 1 Y 1 C GLN 3   ? B GLN 1   
127 1 Y 1 C GLY 28  ? B GLY 26  
128 1 Y 1 C THR 29  ? B THR 27  
129 1 Y 1 C ILE 30  ? B ILE 28  
130 1 Y 1 C HIS 124 ? B HIS 122 
131 1 Y 1 C HIS 125 ? B HIS 123 
132 1 Y 1 C HIS 126 ? B HIS 124 
133 1 Y 1 C HIS 127 ? B HIS 125 
134 1 Y 1 C HIS 128 ? B HIS 126 
135 1 Y 1 C HIS 129 ? B HIS 127 
136 1 Y 1 C GLU 130 ? B GLU 128 
137 1 Y 1 C PRO 131 ? B PRO 129 
138 1 Y 1 C GLU 132 ? B GLU 130 
139 1 Y 1 C ALA 133 ? B ALA 131 
140 1 Y 1 H GLU -2  ? C GLU 1   
141 1 Y 1 H ILE -1  ? C ILE 2   
142 1 Y 1 H SER 0   ? C SER 3   
143 1 Y 1 H GLU 1   ? C GLU 4   
144 1 Y 1 H SER 51  A C SER 55  
145 1 Y 1 H SER 51  B C SER 56  
146 1 Y 1 H SER 51  C C SER 57  
147 1 Y 1 H SER 51  D C SER 58  
148 1 Y 1 H SER 51  E C SER 59  
149 1 Y 1 H SER 62  ? C SER 66  
150 1 Y 1 H THR 73  ? C THR 77  
151 1 Y 1 H SER 74  ? C SER 78  
152 1 Y 1 H LYS 75  ? C LYS 79  
153 1 Y 1 H SER 141 A C SER 146 
154 1 Y 1 H LYS 141 B C LYS 147 
155 1 Y 1 H SER 141 C C SER 148 
156 1 Y 1 H THR 141 D C THR 149 
157 1 Y 1 H SER 141 E C SER 150 
158 1 Y 1 H GLY 141 F C GLY 151 
159 1 Y 1 H GLY 141 G C GLY 152 
160 1 Y 1 H PHE 152 A C PHE 164 
161 1 Y 1 H PRO 152 B C PRO 165 
162 1 Y 1 H GLU 152 C C GLU 166 
163 1 Y 1 H PRO 152 D C PRO 167 
164 1 Y 1 H ASN 157 A C ASN 173 
165 1 Y 1 H SER 157 B C SER 174 
166 1 Y 1 H GLY 157 C C GLY 175 
167 1 Y 1 H ALA 157 D C ALA 176 
168 1 Y 1 H LEU 157 E C LEU 177 
169 1 Y 1 H THR 157 F C THR 178 
170 1 Y 1 H SER 157 G C SER 179 
171 1 Y 1 H GLY 157 H C GLY 180 
172 1 Y 1 H SER 173 ? C SER 191 
173 1 Y 1 H GLY 174 ? C GLY 192 
174 1 Y 1 H LEU 175 ? C LEU 193 
175 1 Y 1 H TYR 176 ? C TYR 194 
176 1 Y 1 H VAL 184 ? C VAL 202 
177 1 Y 1 H PRO 185 ? C PRO 203 
178 1 Y 1 H SER 186 ? C SER 204 
179 1 Y 1 H SER 187 ? C SER 205 
180 1 Y 1 H SER 188 ? C SER 206 
181 1 Y 1 H LEU 189 ? C LEU 207 
182 1 Y 1 H GLY 190 ? C GLY 208 
183 1 Y 1 H THR 191 ? C THR 209 
184 1 Y 1 H GLN 192 ? C GLN 210 
185 1 Y 1 H THR 193 ? C THR 211 
186 1 Y 1 H ASP 208 ? C ASP 226 
187 1 Y 1 H LYS 209 ? C LYS 227 
188 1 Y 1 H LYS 214 ? C LYS 232 
189 1 Y 1 H SER 215 ? C SER 233 
190 1 Y 1 H CYS 216 ? C CYS 234 
191 1 Y 1 H ASP 217 ? C ASP 235 
192 1 Y 1 H LYS 218 ? C LYS 236 
193 1 Y 1 H THR 219 ? C THR 237 
194 1 Y 1 H HIS 220 ? C HIS 238 
195 1 Y 1 H THR 221 ? C THR 239 
196 1 Y 1 L SER 0   ? D SER 1   
197 1 Y 1 L ASP 1   ? D ASP 2   
198 1 Y 1 L ILE 2   ? D ILE 3   
199 1 Y 1 L GLN 3   ? D GLN 4   
200 1 Y 1 L MET 4   ? D MET 5   
201 1 Y 1 L SER 7   ? D SER 8   
202 1 Y 1 L PRO 8   ? D PRO 9   
203 1 Y 1 L VAL 19  ? D VAL 20  
204 1 Y 1 L SER 26  ? D SER 27  
205 1 Y 1 L GLN 27  ? D GLN 28  
206 1 Y 1 L SER 28  ? D SER 29  
207 1 Y 1 L VAL 29  ? D VAL 30  
208 1 Y 1 L SER 67  ? D SER 68  
209 1 Y 1 L GLY 212 ? D GLY 213 
210 1 Y 1 L GLU 213 ? D GLU 214 
211 1 Y 1 L CYS 214 ? D CYS 215 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1BNM C01  C N N 1   
A1BNM C02  C N R 2   
A1BNM C04  C N S 3   
A1BNM C05  C N N 4   
A1BNM C06  C N N 5   
A1BNM C07  C N S 6   
A1BNM C08  C N N 7   
A1BNM C09  C N S 8   
A1BNM C10  C N N 9   
A1BNM C12  C N N 10  
A1BNM C14  C N N 11  
A1BNM C15  C Y N 12  
A1BNM C16  C Y N 13  
A1BNM C17  C Y N 14  
A1BNM C18  C Y N 15  
A1BNM C19  C Y N 16  
A1BNM C21  C Y N 17  
A1BNM C22  C N N 18  
A1BNM C23  C Y N 19  
A1BNM C24  C Y N 20  
A1BNM C27  C Y N 21  
A1BNM C28  C N N 22  
A1BNM C29  C N N 23  
A1BNM N03  N N N 24  
A1BNM N25  N Y N 25  
A1BNM N26  N Y N 26  
A1BNM O11  O N N 27  
A1BNM O13  O N N 28  
A1BNM O20  O N N 29  
A1BNM H1   H N N 30  
A1BNM H2   H N N 31  
A1BNM H3   H N N 32  
A1BNM H4   H N N 33  
A1BNM H5   H N N 34  
A1BNM H6   H N N 35  
A1BNM H7   H N N 36  
A1BNM H8   H N N 37  
A1BNM H9   H N N 38  
A1BNM H10  H N N 39  
A1BNM H11  H N N 40  
A1BNM H12  H N N 41  
A1BNM H13  H N N 42  
A1BNM H14  H N N 43  
A1BNM H15  H N N 44  
A1BNM H16  H N N 45  
A1BNM H17  H N N 46  
A1BNM H18  H N N 47  
A1BNM H19  H N N 48  
A1BNM H20  H N N 49  
A1BNM H21  H N N 50  
A1BNM H22  H N N 51  
A1BNM H23  H N N 52  
A1BNM H24  H N N 53  
A1BNM H25  H N N 54  
A1BNM H26  H N N 55  
A1BNM H27  H N N 56  
A1BNM H28  H N N 57  
A1BNM H30  H N N 58  
ALA   N    N N N 59  
ALA   CA   C N S 60  
ALA   C    C N N 61  
ALA   O    O N N 62  
ALA   CB   C N N 63  
ALA   OXT  O N N 64  
ALA   H    H N N 65  
ALA   H2   H N N 66  
ALA   HA   H N N 67  
ALA   HB1  H N N 68  
ALA   HB2  H N N 69  
ALA   HB3  H N N 70  
ALA   HXT  H N N 71  
ARG   N    N N N 72  
ARG   CA   C N S 73  
ARG   C    C N N 74  
ARG   O    O N N 75  
ARG   CB   C N N 76  
ARG   CG   C N N 77  
ARG   CD   C N N 78  
ARG   NE   N N N 79  
ARG   CZ   C N N 80  
ARG   NH1  N N N 81  
ARG   NH2  N N N 82  
ARG   OXT  O N N 83  
ARG   H    H N N 84  
ARG   H2   H N N 85  
ARG   HA   H N N 86  
ARG   HB2  H N N 87  
ARG   HB3  H N N 88  
ARG   HG2  H N N 89  
ARG   HG3  H N N 90  
ARG   HD2  H N N 91  
ARG   HD3  H N N 92  
ARG   HE   H N N 93  
ARG   HH11 H N N 94  
ARG   HH12 H N N 95  
ARG   HH21 H N N 96  
ARG   HH22 H N N 97  
ARG   HXT  H N N 98  
ASN   N    N N N 99  
ASN   CA   C N S 100 
ASN   C    C N N 101 
ASN   O    O N N 102 
ASN   CB   C N N 103 
ASN   CG   C N N 104 
ASN   OD1  O N N 105 
ASN   ND2  N N N 106 
ASN   OXT  O N N 107 
ASN   H    H N N 108 
ASN   H2   H N N 109 
ASN   HA   H N N 110 
ASN   HB2  H N N 111 
ASN   HB3  H N N 112 
ASN   HD21 H N N 113 
ASN   HD22 H N N 114 
ASN   HXT  H N N 115 
ASP   N    N N N 116 
ASP   CA   C N S 117 
ASP   C    C N N 118 
ASP   O    O N N 119 
ASP   CB   C N N 120 
ASP   CG   C N N 121 
ASP   OD1  O N N 122 
ASP   OD2  O N N 123 
ASP   OXT  O N N 124 
ASP   H    H N N 125 
ASP   H2   H N N 126 
ASP   HA   H N N 127 
ASP   HB2  H N N 128 
ASP   HB3  H N N 129 
ASP   HD2  H N N 130 
ASP   HXT  H N N 131 
CYS   N    N N N 132 
CYS   CA   C N R 133 
CYS   C    C N N 134 
CYS   O    O N N 135 
CYS   CB   C N N 136 
CYS   SG   S N N 137 
CYS   OXT  O N N 138 
CYS   H    H N N 139 
CYS   H2   H N N 140 
CYS   HA   H N N 141 
CYS   HB2  H N N 142 
CYS   HB3  H N N 143 
CYS   HG   H N N 144 
CYS   HXT  H N N 145 
GLN   N    N N N 146 
GLN   CA   C N S 147 
GLN   C    C N N 148 
GLN   O    O N N 149 
GLN   CB   C N N 150 
GLN   CG   C N N 151 
GLN   CD   C N N 152 
GLN   OE1  O N N 153 
GLN   NE2  N N N 154 
GLN   OXT  O N N 155 
GLN   H    H N N 156 
GLN   H2   H N N 157 
GLN   HA   H N N 158 
GLN   HB2  H N N 159 
GLN   HB3  H N N 160 
GLN   HG2  H N N 161 
GLN   HG3  H N N 162 
GLN   HE21 H N N 163 
GLN   HE22 H N N 164 
GLN   HXT  H N N 165 
GLU   N    N N N 166 
GLU   CA   C N S 167 
GLU   C    C N N 168 
GLU   O    O N N 169 
GLU   CB   C N N 170 
GLU   CG   C N N 171 
GLU   CD   C N N 172 
GLU   OE1  O N N 173 
GLU   OE2  O N N 174 
GLU   OXT  O N N 175 
GLU   H    H N N 176 
GLU   H2   H N N 177 
GLU   HA   H N N 178 
GLU   HB2  H N N 179 
GLU   HB3  H N N 180 
GLU   HG2  H N N 181 
GLU   HG3  H N N 182 
GLU   HE2  H N N 183 
GLU   HXT  H N N 184 
GLY   N    N N N 185 
GLY   CA   C N N 186 
GLY   C    C N N 187 
GLY   O    O N N 188 
GLY   OXT  O N N 189 
GLY   H    H N N 190 
GLY   H2   H N N 191 
GLY   HA2  H N N 192 
GLY   HA3  H N N 193 
GLY   HXT  H N N 194 
HIS   N    N N N 195 
HIS   CA   C N S 196 
HIS   C    C N N 197 
HIS   O    O N N 198 
HIS   CB   C N N 199 
HIS   CG   C Y N 200 
HIS   ND1  N Y N 201 
HIS   CD2  C Y N 202 
HIS   CE1  C Y N 203 
HIS   NE2  N Y N 204 
HIS   OXT  O N N 205 
HIS   H    H N N 206 
HIS   H2   H N N 207 
HIS   HA   H N N 208 
HIS   HB2  H N N 209 
HIS   HB3  H N N 210 
HIS   HD1  H N N 211 
HIS   HD2  H N N 212 
HIS   HE1  H N N 213 
HIS   HE2  H N N 214 
HIS   HXT  H N N 215 
ILE   N    N N N 216 
ILE   CA   C N S 217 
ILE   C    C N N 218 
ILE   O    O N N 219 
ILE   CB   C N S 220 
ILE   CG1  C N N 221 
ILE   CG2  C N N 222 
ILE   CD1  C N N 223 
ILE   OXT  O N N 224 
ILE   H    H N N 225 
ILE   H2   H N N 226 
ILE   HA   H N N 227 
ILE   HB   H N N 228 
ILE   HG12 H N N 229 
ILE   HG13 H N N 230 
ILE   HG21 H N N 231 
ILE   HG22 H N N 232 
ILE   HG23 H N N 233 
ILE   HD11 H N N 234 
ILE   HD12 H N N 235 
ILE   HD13 H N N 236 
ILE   HXT  H N N 237 
LEU   N    N N N 238 
LEU   CA   C N S 239 
LEU   C    C N N 240 
LEU   O    O N N 241 
LEU   CB   C N N 242 
LEU   CG   C N N 243 
LEU   CD1  C N N 244 
LEU   CD2  C N N 245 
LEU   OXT  O N N 246 
LEU   H    H N N 247 
LEU   H2   H N N 248 
LEU   HA   H N N 249 
LEU   HB2  H N N 250 
LEU   HB3  H N N 251 
LEU   HG   H N N 252 
LEU   HD11 H N N 253 
LEU   HD12 H N N 254 
LEU   HD13 H N N 255 
LEU   HD21 H N N 256 
LEU   HD22 H N N 257 
LEU   HD23 H N N 258 
LEU   HXT  H N N 259 
LYS   N    N N N 260 
LYS   CA   C N S 261 
LYS   C    C N N 262 
LYS   O    O N N 263 
LYS   CB   C N N 264 
LYS   CG   C N N 265 
LYS   CD   C N N 266 
LYS   CE   C N N 267 
LYS   NZ   N N N 268 
LYS   OXT  O N N 269 
LYS   H    H N N 270 
LYS   H2   H N N 271 
LYS   HA   H N N 272 
LYS   HB2  H N N 273 
LYS   HB3  H N N 274 
LYS   HG2  H N N 275 
LYS   HG3  H N N 276 
LYS   HD2  H N N 277 
LYS   HD3  H N N 278 
LYS   HE2  H N N 279 
LYS   HE3  H N N 280 
LYS   HZ1  H N N 281 
LYS   HZ2  H N N 282 
LYS   HZ3  H N N 283 
LYS   HXT  H N N 284 
MET   N    N N N 285 
MET   CA   C N S 286 
MET   C    C N N 287 
MET   O    O N N 288 
MET   CB   C N N 289 
MET   CG   C N N 290 
MET   SD   S N N 291 
MET   CE   C N N 292 
MET   OXT  O N N 293 
MET   H    H N N 294 
MET   H2   H N N 295 
MET   HA   H N N 296 
MET   HB2  H N N 297 
MET   HB3  H N N 298 
MET   HG2  H N N 299 
MET   HG3  H N N 300 
MET   HE1  H N N 301 
MET   HE2  H N N 302 
MET   HE3  H N N 303 
MET   HXT  H N N 304 
PHE   N    N N N 305 
PHE   CA   C N S 306 
PHE   C    C N N 307 
PHE   O    O N N 308 
PHE   CB   C N N 309 
PHE   CG   C Y N 310 
PHE   CD1  C Y N 311 
PHE   CD2  C Y N 312 
PHE   CE1  C Y N 313 
PHE   CE2  C Y N 314 
PHE   CZ   C Y N 315 
PHE   OXT  O N N 316 
PHE   H    H N N 317 
PHE   H2   H N N 318 
PHE   HA   H N N 319 
PHE   HB2  H N N 320 
PHE   HB3  H N N 321 
PHE   HD1  H N N 322 
PHE   HD2  H N N 323 
PHE   HE1  H N N 324 
PHE   HE2  H N N 325 
PHE   HZ   H N N 326 
PHE   HXT  H N N 327 
PRO   N    N N N 328 
PRO   CA   C N S 329 
PRO   C    C N N 330 
PRO   O    O N N 331 
PRO   CB   C N N 332 
PRO   CG   C N N 333 
PRO   CD   C N N 334 
PRO   OXT  O N N 335 
PRO   H    H N N 336 
PRO   HA   H N N 337 
PRO   HB2  H N N 338 
PRO   HB3  H N N 339 
PRO   HG2  H N N 340 
PRO   HG3  H N N 341 
PRO   HD2  H N N 342 
PRO   HD3  H N N 343 
PRO   HXT  H N N 344 
SER   N    N N N 345 
SER   CA   C N S 346 
SER   C    C N N 347 
SER   O    O N N 348 
SER   CB   C N N 349 
SER   OG   O N N 350 
SER   OXT  O N N 351 
SER   H    H N N 352 
SER   H2   H N N 353 
SER   HA   H N N 354 
SER   HB2  H N N 355 
SER   HB3  H N N 356 
SER   HG   H N N 357 
SER   HXT  H N N 358 
THR   N    N N N 359 
THR   CA   C N S 360 
THR   C    C N N 361 
THR   O    O N N 362 
THR   CB   C N R 363 
THR   OG1  O N N 364 
THR   CG2  C N N 365 
THR   OXT  O N N 366 
THR   H    H N N 367 
THR   H2   H N N 368 
THR   HA   H N N 369 
THR   HB   H N N 370 
THR   HG1  H N N 371 
THR   HG21 H N N 372 
THR   HG22 H N N 373 
THR   HG23 H N N 374 
THR   HXT  H N N 375 
TRP   N    N N N 376 
TRP   CA   C N S 377 
TRP   C    C N N 378 
TRP   O    O N N 379 
TRP   CB   C N N 380 
TRP   CG   C Y N 381 
TRP   CD1  C Y N 382 
TRP   CD2  C Y N 383 
TRP   NE1  N Y N 384 
TRP   CE2  C Y N 385 
TRP   CE3  C Y N 386 
TRP   CZ2  C Y N 387 
TRP   CZ3  C Y N 388 
TRP   CH2  C Y N 389 
TRP   OXT  O N N 390 
TRP   H    H N N 391 
TRP   H2   H N N 392 
TRP   HA   H N N 393 
TRP   HB2  H N N 394 
TRP   HB3  H N N 395 
TRP   HD1  H N N 396 
TRP   HE1  H N N 397 
TRP   HE3  H N N 398 
TRP   HZ2  H N N 399 
TRP   HZ3  H N N 400 
TRP   HH2  H N N 401 
TRP   HXT  H N N 402 
TYR   N    N N N 403 
TYR   CA   C N S 404 
TYR   C    C N N 405 
TYR   O    O N N 406 
TYR   CB   C N N 407 
TYR   CG   C Y N 408 
TYR   CD1  C Y N 409 
TYR   CD2  C Y N 410 
TYR   CE1  C Y N 411 
TYR   CE2  C Y N 412 
TYR   CZ   C Y N 413 
TYR   OH   O N N 414 
TYR   OXT  O N N 415 
TYR   H    H N N 416 
TYR   H2   H N N 417 
TYR   HA   H N N 418 
TYR   HB2  H N N 419 
TYR   HB3  H N N 420 
TYR   HD1  H N N 421 
TYR   HD2  H N N 422 
TYR   HE1  H N N 423 
TYR   HE2  H N N 424 
TYR   HH   H N N 425 
TYR   HXT  H N N 426 
VAL   N    N N N 427 
VAL   CA   C N S 428 
VAL   C    C N N 429 
VAL   O    O N N 430 
VAL   CB   C N N 431 
VAL   CG1  C N N 432 
VAL   CG2  C N N 433 
VAL   OXT  O N N 434 
VAL   H    H N N 435 
VAL   H2   H N N 436 
VAL   HA   H N N 437 
VAL   HB   H N N 438 
VAL   HG11 H N N 439 
VAL   HG12 H N N 440 
VAL   HG13 H N N 441 
VAL   HG21 H N N 442 
VAL   HG22 H N N 443 
VAL   HG23 H N N 444 
VAL   HXT  H N N 445 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1BNM C12 O11  sing N N 1   
A1BNM O11 C10  sing N N 2   
A1BNM O13 C10  doub N N 3   
A1BNM C10 C09  sing N N 4   
A1BNM C17 C16  doub Y N 5   
A1BNM C17 C18  sing Y N 6   
A1BNM C16 C15  sing Y N 7   
A1BNM C09 C08  sing N N 8   
A1BNM C09 C04  sing N N 9   
A1BNM C08 C07  sing N N 10  
A1BNM C05 C04  sing N N 11  
A1BNM C05 C06  doub N N 12  
A1BNM C04 N03  sing N N 13  
A1BNM C06 C15  sing N N 14  
A1BNM C06 C07  sing N N 15  
A1BNM C18 C19  doub Y N 16  
A1BNM C15 C21  doub Y N 17  
A1BNM C07 C14  sing N N 18  
A1BNM C07 C02  sing N N 19  
A1BNM C28 N25  sing N N 20  
A1BNM C28 C29  sing N N 21  
A1BNM N03 C02  sing N N 22  
A1BNM N03 C22  sing N N 23  
A1BNM C24 N25  sing Y N 24  
A1BNM C24 C23  doub Y N 25  
A1BNM C21 C19  sing Y N 26  
A1BNM C19 O20  sing N N 27  
A1BNM N25 N26  sing Y N 28  
A1BNM C02 C01  sing N N 29  
A1BNM C23 C22  sing N N 30  
A1BNM C23 C27  sing Y N 31  
A1BNM N26 C27  doub Y N 32  
A1BNM C01 H1   sing N N 33  
A1BNM C01 H2   sing N N 34  
A1BNM C01 H3   sing N N 35  
A1BNM C02 H4   sing N N 36  
A1BNM C04 H5   sing N N 37  
A1BNM C05 H6   sing N N 38  
A1BNM C08 H7   sing N N 39  
A1BNM C08 H8   sing N N 40  
A1BNM C09 H9   sing N N 41  
A1BNM C12 H10  sing N N 42  
A1BNM C12 H11  sing N N 43  
A1BNM C12 H12  sing N N 44  
A1BNM C14 H13  sing N N 45  
A1BNM C14 H14  sing N N 46  
A1BNM C14 H15  sing N N 47  
A1BNM C16 H16  sing N N 48  
A1BNM C17 H17  sing N N 49  
A1BNM C18 H18  sing N N 50  
A1BNM C21 H19  sing N N 51  
A1BNM C22 H20  sing N N 52  
A1BNM C22 H21  sing N N 53  
A1BNM C24 H22  sing N N 54  
A1BNM C27 H23  sing N N 55  
A1BNM C28 H24  sing N N 56  
A1BNM C28 H25  sing N N 57  
A1BNM C29 H26  sing N N 58  
A1BNM C29 H27  sing N N 59  
A1BNM C29 H28  sing N N 60  
A1BNM O20 H30  sing N N 61  
ALA   N   CA   sing N N 62  
ALA   N   H    sing N N 63  
ALA   N   H2   sing N N 64  
ALA   CA  C    sing N N 65  
ALA   CA  CB   sing N N 66  
ALA   CA  HA   sing N N 67  
ALA   C   O    doub N N 68  
ALA   C   OXT  sing N N 69  
ALA   CB  HB1  sing N N 70  
ALA   CB  HB2  sing N N 71  
ALA   CB  HB3  sing N N 72  
ALA   OXT HXT  sing N N 73  
ARG   N   CA   sing N N 74  
ARG   N   H    sing N N 75  
ARG   N   H2   sing N N 76  
ARG   CA  C    sing N N 77  
ARG   CA  CB   sing N N 78  
ARG   CA  HA   sing N N 79  
ARG   C   O    doub N N 80  
ARG   C   OXT  sing N N 81  
ARG   CB  CG   sing N N 82  
ARG   CB  HB2  sing N N 83  
ARG   CB  HB3  sing N N 84  
ARG   CG  CD   sing N N 85  
ARG   CG  HG2  sing N N 86  
ARG   CG  HG3  sing N N 87  
ARG   CD  NE   sing N N 88  
ARG   CD  HD2  sing N N 89  
ARG   CD  HD3  sing N N 90  
ARG   NE  CZ   sing N N 91  
ARG   NE  HE   sing N N 92  
ARG   CZ  NH1  sing N N 93  
ARG   CZ  NH2  doub N N 94  
ARG   NH1 HH11 sing N N 95  
ARG   NH1 HH12 sing N N 96  
ARG   NH2 HH21 sing N N 97  
ARG   NH2 HH22 sing N N 98  
ARG   OXT HXT  sing N N 99  
ASN   N   CA   sing N N 100 
ASN   N   H    sing N N 101 
ASN   N   H2   sing N N 102 
ASN   CA  C    sing N N 103 
ASN   CA  CB   sing N N 104 
ASN   CA  HA   sing N N 105 
ASN   C   O    doub N N 106 
ASN   C   OXT  sing N N 107 
ASN   CB  CG   sing N N 108 
ASN   CB  HB2  sing N N 109 
ASN   CB  HB3  sing N N 110 
ASN   CG  OD1  doub N N 111 
ASN   CG  ND2  sing N N 112 
ASN   ND2 HD21 sing N N 113 
ASN   ND2 HD22 sing N N 114 
ASN   OXT HXT  sing N N 115 
ASP   N   CA   sing N N 116 
ASP   N   H    sing N N 117 
ASP   N   H2   sing N N 118 
ASP   CA  C    sing N N 119 
ASP   CA  CB   sing N N 120 
ASP   CA  HA   sing N N 121 
ASP   C   O    doub N N 122 
ASP   C   OXT  sing N N 123 
ASP   CB  CG   sing N N 124 
ASP   CB  HB2  sing N N 125 
ASP   CB  HB3  sing N N 126 
ASP   CG  OD1  doub N N 127 
ASP   CG  OD2  sing N N 128 
ASP   OD2 HD2  sing N N 129 
ASP   OXT HXT  sing N N 130 
CYS   N   CA   sing N N 131 
CYS   N   H    sing N N 132 
CYS   N   H2   sing N N 133 
CYS   CA  C    sing N N 134 
CYS   CA  CB   sing N N 135 
CYS   CA  HA   sing N N 136 
CYS   C   O    doub N N 137 
CYS   C   OXT  sing N N 138 
CYS   CB  SG   sing N N 139 
CYS   CB  HB2  sing N N 140 
CYS   CB  HB3  sing N N 141 
CYS   SG  HG   sing N N 142 
CYS   OXT HXT  sing N N 143 
GLN   N   CA   sing N N 144 
GLN   N   H    sing N N 145 
GLN   N   H2   sing N N 146 
GLN   CA  C    sing N N 147 
GLN   CA  CB   sing N N 148 
GLN   CA  HA   sing N N 149 
GLN   C   O    doub N N 150 
GLN   C   OXT  sing N N 151 
GLN   CB  CG   sing N N 152 
GLN   CB  HB2  sing N N 153 
GLN   CB  HB3  sing N N 154 
GLN   CG  CD   sing N N 155 
GLN   CG  HG2  sing N N 156 
GLN   CG  HG3  sing N N 157 
GLN   CD  OE1  doub N N 158 
GLN   CD  NE2  sing N N 159 
GLN   NE2 HE21 sing N N 160 
GLN   NE2 HE22 sing N N 161 
GLN   OXT HXT  sing N N 162 
GLU   N   CA   sing N N 163 
GLU   N   H    sing N N 164 
GLU   N   H2   sing N N 165 
GLU   CA  C    sing N N 166 
GLU   CA  CB   sing N N 167 
GLU   CA  HA   sing N N 168 
GLU   C   O    doub N N 169 
GLU   C   OXT  sing N N 170 
GLU   CB  CG   sing N N 171 
GLU   CB  HB2  sing N N 172 
GLU   CB  HB3  sing N N 173 
GLU   CG  CD   sing N N 174 
GLU   CG  HG2  sing N N 175 
GLU   CG  HG3  sing N N 176 
GLU   CD  OE1  doub N N 177 
GLU   CD  OE2  sing N N 178 
GLU   OE2 HE2  sing N N 179 
GLU   OXT HXT  sing N N 180 
GLY   N   CA   sing N N 181 
GLY   N   H    sing N N 182 
GLY   N   H2   sing N N 183 
GLY   CA  C    sing N N 184 
GLY   CA  HA2  sing N N 185 
GLY   CA  HA3  sing N N 186 
GLY   C   O    doub N N 187 
GLY   C   OXT  sing N N 188 
GLY   OXT HXT  sing N N 189 
HIS   N   CA   sing N N 190 
HIS   N   H    sing N N 191 
HIS   N   H2   sing N N 192 
HIS   CA  C    sing N N 193 
HIS   CA  CB   sing N N 194 
HIS   CA  HA   sing N N 195 
HIS   C   O    doub N N 196 
HIS   C   OXT  sing N N 197 
HIS   CB  CG   sing N N 198 
HIS   CB  HB2  sing N N 199 
HIS   CB  HB3  sing N N 200 
HIS   CG  ND1  sing Y N 201 
HIS   CG  CD2  doub Y N 202 
HIS   ND1 CE1  doub Y N 203 
HIS   ND1 HD1  sing N N 204 
HIS   CD2 NE2  sing Y N 205 
HIS   CD2 HD2  sing N N 206 
HIS   CE1 NE2  sing Y N 207 
HIS   CE1 HE1  sing N N 208 
HIS   NE2 HE2  sing N N 209 
HIS   OXT HXT  sing N N 210 
ILE   N   CA   sing N N 211 
ILE   N   H    sing N N 212 
ILE   N   H2   sing N N 213 
ILE   CA  C    sing N N 214 
ILE   CA  CB   sing N N 215 
ILE   CA  HA   sing N N 216 
ILE   C   O    doub N N 217 
ILE   C   OXT  sing N N 218 
ILE   CB  CG1  sing N N 219 
ILE   CB  CG2  sing N N 220 
ILE   CB  HB   sing N N 221 
ILE   CG1 CD1  sing N N 222 
ILE   CG1 HG12 sing N N 223 
ILE   CG1 HG13 sing N N 224 
ILE   CG2 HG21 sing N N 225 
ILE   CG2 HG22 sing N N 226 
ILE   CG2 HG23 sing N N 227 
ILE   CD1 HD11 sing N N 228 
ILE   CD1 HD12 sing N N 229 
ILE   CD1 HD13 sing N N 230 
ILE   OXT HXT  sing N N 231 
LEU   N   CA   sing N N 232 
LEU   N   H    sing N N 233 
LEU   N   H2   sing N N 234 
LEU   CA  C    sing N N 235 
LEU   CA  CB   sing N N 236 
LEU   CA  HA   sing N N 237 
LEU   C   O    doub N N 238 
LEU   C   OXT  sing N N 239 
LEU   CB  CG   sing N N 240 
LEU   CB  HB2  sing N N 241 
LEU   CB  HB3  sing N N 242 
LEU   CG  CD1  sing N N 243 
LEU   CG  CD2  sing N N 244 
LEU   CG  HG   sing N N 245 
LEU   CD1 HD11 sing N N 246 
LEU   CD1 HD12 sing N N 247 
LEU   CD1 HD13 sing N N 248 
LEU   CD2 HD21 sing N N 249 
LEU   CD2 HD22 sing N N 250 
LEU   CD2 HD23 sing N N 251 
LEU   OXT HXT  sing N N 252 
LYS   N   CA   sing N N 253 
LYS   N   H    sing N N 254 
LYS   N   H2   sing N N 255 
LYS   CA  C    sing N N 256 
LYS   CA  CB   sing N N 257 
LYS   CA  HA   sing N N 258 
LYS   C   O    doub N N 259 
LYS   C   OXT  sing N N 260 
LYS   CB  CG   sing N N 261 
LYS   CB  HB2  sing N N 262 
LYS   CB  HB3  sing N N 263 
LYS   CG  CD   sing N N 264 
LYS   CG  HG2  sing N N 265 
LYS   CG  HG3  sing N N 266 
LYS   CD  CE   sing N N 267 
LYS   CD  HD2  sing N N 268 
LYS   CD  HD3  sing N N 269 
LYS   CE  NZ   sing N N 270 
LYS   CE  HE2  sing N N 271 
LYS   CE  HE3  sing N N 272 
LYS   NZ  HZ1  sing N N 273 
LYS   NZ  HZ2  sing N N 274 
LYS   NZ  HZ3  sing N N 275 
LYS   OXT HXT  sing N N 276 
MET   N   CA   sing N N 277 
MET   N   H    sing N N 278 
MET   N   H2   sing N N 279 
MET   CA  C    sing N N 280 
MET   CA  CB   sing N N 281 
MET   CA  HA   sing N N 282 
MET   C   O    doub N N 283 
MET   C   OXT  sing N N 284 
MET   CB  CG   sing N N 285 
MET   CB  HB2  sing N N 286 
MET   CB  HB3  sing N N 287 
MET   CG  SD   sing N N 288 
MET   CG  HG2  sing N N 289 
MET   CG  HG3  sing N N 290 
MET   SD  CE   sing N N 291 
MET   CE  HE1  sing N N 292 
MET   CE  HE2  sing N N 293 
MET   CE  HE3  sing N N 294 
MET   OXT HXT  sing N N 295 
PHE   N   CA   sing N N 296 
PHE   N   H    sing N N 297 
PHE   N   H2   sing N N 298 
PHE   CA  C    sing N N 299 
PHE   CA  CB   sing N N 300 
PHE   CA  HA   sing N N 301 
PHE   C   O    doub N N 302 
PHE   C   OXT  sing N N 303 
PHE   CB  CG   sing N N 304 
PHE   CB  HB2  sing N N 305 
PHE   CB  HB3  sing N N 306 
PHE   CG  CD1  doub Y N 307 
PHE   CG  CD2  sing Y N 308 
PHE   CD1 CE1  sing Y N 309 
PHE   CD1 HD1  sing N N 310 
PHE   CD2 CE2  doub Y N 311 
PHE   CD2 HD2  sing N N 312 
PHE   CE1 CZ   doub Y N 313 
PHE   CE1 HE1  sing N N 314 
PHE   CE2 CZ   sing Y N 315 
PHE   CE2 HE2  sing N N 316 
PHE   CZ  HZ   sing N N 317 
PHE   OXT HXT  sing N N 318 
PRO   N   CA   sing N N 319 
PRO   N   CD   sing N N 320 
PRO   N   H    sing N N 321 
PRO   CA  C    sing N N 322 
PRO   CA  CB   sing N N 323 
PRO   CA  HA   sing N N 324 
PRO   C   O    doub N N 325 
PRO   C   OXT  sing N N 326 
PRO   CB  CG   sing N N 327 
PRO   CB  HB2  sing N N 328 
PRO   CB  HB3  sing N N 329 
PRO   CG  CD   sing N N 330 
PRO   CG  HG2  sing N N 331 
PRO   CG  HG3  sing N N 332 
PRO   CD  HD2  sing N N 333 
PRO   CD  HD3  sing N N 334 
PRO   OXT HXT  sing N N 335 
SER   N   CA   sing N N 336 
SER   N   H    sing N N 337 
SER   N   H2   sing N N 338 
SER   CA  C    sing N N 339 
SER   CA  CB   sing N N 340 
SER   CA  HA   sing N N 341 
SER   C   O    doub N N 342 
SER   C   OXT  sing N N 343 
SER   CB  OG   sing N N 344 
SER   CB  HB2  sing N N 345 
SER   CB  HB3  sing N N 346 
SER   OG  HG   sing N N 347 
SER   OXT HXT  sing N N 348 
THR   N   CA   sing N N 349 
THR   N   H    sing N N 350 
THR   N   H2   sing N N 351 
THR   CA  C    sing N N 352 
THR   CA  CB   sing N N 353 
THR   CA  HA   sing N N 354 
THR   C   O    doub N N 355 
THR   C   OXT  sing N N 356 
THR   CB  OG1  sing N N 357 
THR   CB  CG2  sing N N 358 
THR   CB  HB   sing N N 359 
THR   OG1 HG1  sing N N 360 
THR   CG2 HG21 sing N N 361 
THR   CG2 HG22 sing N N 362 
THR   CG2 HG23 sing N N 363 
THR   OXT HXT  sing N N 364 
TRP   N   CA   sing N N 365 
TRP   N   H    sing N N 366 
TRP   N   H2   sing N N 367 
TRP   CA  C    sing N N 368 
TRP   CA  CB   sing N N 369 
TRP   CA  HA   sing N N 370 
TRP   C   O    doub N N 371 
TRP   C   OXT  sing N N 372 
TRP   CB  CG   sing N N 373 
TRP   CB  HB2  sing N N 374 
TRP   CB  HB3  sing N N 375 
TRP   CG  CD1  doub Y N 376 
TRP   CG  CD2  sing Y N 377 
TRP   CD1 NE1  sing Y N 378 
TRP   CD1 HD1  sing N N 379 
TRP   CD2 CE2  doub Y N 380 
TRP   CD2 CE3  sing Y N 381 
TRP   NE1 CE2  sing Y N 382 
TRP   NE1 HE1  sing N N 383 
TRP   CE2 CZ2  sing Y N 384 
TRP   CE3 CZ3  doub Y N 385 
TRP   CE3 HE3  sing N N 386 
TRP   CZ2 CH2  doub Y N 387 
TRP   CZ2 HZ2  sing N N 388 
TRP   CZ3 CH2  sing Y N 389 
TRP   CZ3 HZ3  sing N N 390 
TRP   CH2 HH2  sing N N 391 
TRP   OXT HXT  sing N N 392 
TYR   N   CA   sing N N 393 
TYR   N   H    sing N N 394 
TYR   N   H2   sing N N 395 
TYR   CA  C    sing N N 396 
TYR   CA  CB   sing N N 397 
TYR   CA  HA   sing N N 398 
TYR   C   O    doub N N 399 
TYR   C   OXT  sing N N 400 
TYR   CB  CG   sing N N 401 
TYR   CB  HB2  sing N N 402 
TYR   CB  HB3  sing N N 403 
TYR   CG  CD1  doub Y N 404 
TYR   CG  CD2  sing Y N 405 
TYR   CD1 CE1  sing Y N 406 
TYR   CD1 HD1  sing N N 407 
TYR   CD2 CE2  doub Y N 408 
TYR   CD2 HD2  sing N N 409 
TYR   CE1 CZ   doub Y N 410 
TYR   CE1 HE1  sing N N 411 
TYR   CE2 CZ   sing Y N 412 
TYR   CE2 HE2  sing N N 413 
TYR   CZ  OH   sing N N 414 
TYR   OH  HH   sing N N 415 
TYR   OXT HXT  sing N N 416 
VAL   N   CA   sing N N 417 
VAL   N   H    sing N N 418 
VAL   N   H2   sing N N 419 
VAL   CA  C    sing N N 420 
VAL   CA  CB   sing N N 421 
VAL   CA  HA   sing N N 422 
VAL   C   O    doub N N 423 
VAL   C   OXT  sing N N 424 
VAL   CB  CG1  sing N N 425 
VAL   CB  CG2  sing N N 426 
VAL   CB  HB   sing N N 427 
VAL   CG1 HG11 sing N N 428 
VAL   CG1 HG12 sing N N 429 
VAL   CG1 HG13 sing N N 430 
VAL   CG2 HG21 sing N N 431 
VAL   CG2 HG22 sing N N 432 
VAL   CG2 HG23 sing N N 433 
VAL   OXT HXT  sing N N 434 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-01-03 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MQI 
_em_admin.last_update        2025-02-12 
_em_admin.map_release_date   2025-02-12 
_em_admin.title              'Inactive Mu-Opioid Receptor with Nb6M, NabFab, and isoquinuclidine compound#020_E1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                46 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         47.7 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    ? 
_em_imaging_optics.energyfilter_name          ? 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                OTHER 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX 1.21.1_5286: 
'IMAGE ACQUISITION'             ? 3  ? ? 1 ?      ?            
MASKING                         ? 4  ? ? ? ?      ?            
'CTF CORRECTION'                ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'            ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?      ?            
'MODEL FITTING'                 ? 8  ? ? ? ?      ?            
OTHER                           ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ?            
CLASSIFICATION                  ? 12 1 ? ? ?      ?            
RECONSTRUCTION                  ? 13 1 ? ? ?      ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Defense Advanced Research Projects Agency (DARPA)'                                        'United States' HR0011-19-2-0020 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM122481      2 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM122473      3 
# 
_atom_sites.entry_id                    9MQI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET   A 1 78  ? 124.820 124.532 185.243 1.00 118.05 ? 67  MET   A N   1 
ATOM   2    C CA  . MET   A 1 78  ? 125.152 123.166 184.857 1.00 114.69 ? 67  MET   A CA  1 
ATOM   3    C C   . MET   A 1 78  ? 125.602 123.104 183.401 1.00 114.25 ? 67  MET   A C   1 
ATOM   4    O O   . MET   A 1 78  ? 126.797 123.148 183.111 1.00 113.48 ? 67  MET   A O   1 
ATOM   5    C CB  . MET   A 1 78  ? 123.955 122.239 185.079 1.00 110.23 ? 67  MET   A CB  1 
ATOM   6    N N   . ILE   A 1 79  ? 124.631 122.999 182.490 1.00 113.92 ? 68  ILE   A N   1 
ATOM   7    C CA  . ILE   A 1 79  ? 124.943 122.955 181.061 1.00 113.20 ? 68  ILE   A CA  1 
ATOM   8    C C   . ILE   A 1 79  ? 125.591 124.262 180.623 1.00 111.68 ? 68  ILE   A C   1 
ATOM   9    O O   . ILE   A 1 79  ? 126.565 124.273 179.859 1.00 111.39 ? 68  ILE   A O   1 
ATOM   10   C CB  . ILE   A 1 79  ? 123.675 122.650 180.244 1.00 114.02 ? 68  ILE   A CB  1 
ATOM   11   C CG1 . ILE   A 1 79  ? 123.023 121.358 180.739 1.00 112.16 ? 68  ILE   A CG1 1 
ATOM   12   C CG2 . ILE   A 1 79  ? 124.007 122.550 178.763 1.00 110.48 ? 68  ILE   A CG2 1 
ATOM   13   C CD1 . ILE   A 1 79  ? 123.916 120.142 180.625 1.00 106.08 ? 68  ILE   A CD1 1 
ATOM   14   N N   . THR   A 1 80  ? 125.054 125.387 181.100 1.00 111.84 ? 69  THR   A N   1 
ATOM   15   C CA  . THR   A 1 80  ? 125.662 126.678 180.801 1.00 113.65 ? 69  THR   A CA  1 
ATOM   16   C C   . THR   A 1 80  ? 127.070 126.767 181.376 1.00 114.63 ? 69  THR   A C   1 
ATOM   17   O O   . THR   A 1 80  ? 127.979 127.304 180.735 1.00 112.42 ? 69  THR   A O   1 
ATOM   18   C CB  . THR   A 1 80  ? 124.790 127.811 181.344 1.00 112.23 ? 69  THR   A CB  1 
ATOM   19   N N   . ALA   A 1 81  ? 127.268 126.239 182.587 1.00 118.05 ? 70  ALA   A N   1 
ATOM   20   C CA  . ALA   A 1 81  ? 128.586 126.289 183.211 1.00 116.68 ? 70  ALA   A CA  1 
ATOM   21   C C   . ALA   A 1 81  ? 129.614 125.497 182.409 1.00 115.28 ? 70  ALA   A C   1 
ATOM   22   O O   . ALA   A 1 81  ? 130.724 125.983 182.161 1.00 112.05 ? 70  ALA   A O   1 
ATOM   23   C CB  . ALA   A 1 81  ? 128.508 125.767 184.645 1.00 112.82 ? 70  ALA   A CB  1 
ATOM   24   N N   . ILE   A 1 82  ? 129.263 124.281 181.988 1.00 115.06 ? 71  ILE   A N   1 
ATOM   25   C CA  . ILE   A 1 82  ? 130.219 123.486 181.224 1.00 112.48 ? 71  ILE   A CA  1 
ATOM   26   C C   . ILE   A 1 82  ? 130.427 124.075 179.833 1.00 108.47 ? 71  ILE   A C   1 
ATOM   27   O O   . ILE   A 1 82  ? 131.530 123.995 179.285 1.00 104.91 ? 71  ILE   A O   1 
ATOM   28   C CB  . ILE   A 1 82  ? 129.789 122.010 181.151 1.00 111.51 ? 71  ILE   A CB  1 
ATOM   29   C CG1 . ILE   A 1 82  ? 128.356 121.879 180.639 1.00 111.06 ? 71  ILE   A CG1 1 
ATOM   30   C CG2 . ILE   A 1 82  ? 129.926 121.350 182.516 1.00 107.54 ? 71  ILE   A CG2 1 
ATOM   31   C CD1 . ILE   A 1 82  ? 128.170 120.777 179.620 1.00 105.44 ? 71  ILE   A CD1 1 
ATOM   32   N N   . THR   A 1 83  ? 129.390 124.675 179.240 1.00 108.87 ? 72  THR   A N   1 
ATOM   33   C CA  . THR   A 1 83  ? 129.572 125.350 177.958 1.00 108.56 ? 72  THR   A CA  1 
ATOM   34   C C   . THR   A 1 83  ? 130.544 126.519 178.086 1.00 107.54 ? 72  THR   A C   1 
ATOM   35   O O   . THR   A 1 83  ? 131.421 126.707 177.233 1.00 103.07 ? 72  THR   A O   1 
ATOM   36   C CB  . THR   A 1 83  ? 128.223 125.830 177.420 1.00 109.55 ? 72  THR   A CB  1 
ATOM   37   O OG1 . THR   A 1 83  ? 127.349 124.707 177.251 1.00 108.77 ? 72  THR   A OG1 1 
ATOM   38   C CG2 . THR   A 1 83  ? 128.400 126.532 176.082 1.00 105.77 ? 72  THR   A CG2 1 
ATOM   39   N N   . ILE   A 1 84  ? 130.409 127.308 179.154 1.00 110.39 ? 73  ILE   A N   1 
ATOM   40   C CA  . ILE   A 1 84  ? 131.325 128.422 179.385 1.00 108.51 ? 73  ILE   A CA  1 
ATOM   41   C C   . ILE   A 1 84  ? 132.738 127.908 179.626 1.00 104.82 ? 73  ILE   A C   1 
ATOM   42   O O   . ILE   A 1 84  ? 133.716 128.486 179.136 1.00 100.39 ? 73  ILE   A O   1 
ATOM   43   C CB  . ILE   A 1 84  ? 130.825 129.291 180.554 1.00 109.85 ? 73  ILE   A CB  1 
ATOM   44   C CG1 . ILE   A 1 84  ? 129.540 130.024 180.160 1.00 113.87 ? 73  ILE   A CG1 1 
ATOM   45   C CG2 . ILE   A 1 84  ? 131.893 130.284 180.989 1.00 105.78 ? 73  ILE   A CG2 1 
ATOM   46   C CD1 . ILE   A 1 84  ? 128.835 130.688 181.320 1.00 116.60 ? 73  ILE   A CD1 1 
ATOM   47   N N   . MET   A 1 85  ? 132.871 126.817 180.385 1.00 106.63 ? 74  MET   A N   1 
ATOM   48   C CA  . MET   A 1 85  ? 134.192 126.243 180.627 1.00 104.19 ? 74  MET   A CA  1 
ATOM   49   C C   . MET   A 1 85  ? 134.832 125.763 179.329 1.00 96.80  ? 74  MET   A C   1 
ATOM   50   O O   . MET   A 1 85  ? 136.031 125.970 179.106 1.00 91.28  ? 74  MET   A O   1 
ATOM   51   C CB  . MET   A 1 85  ? 134.089 125.094 181.631 1.00 103.42 ? 74  MET   A CB  1 
ATOM   52   C CG  . MET   A 1 85  ? 135.306 124.940 182.529 1.00 98.88  ? 74  MET   A CG  1 
ATOM   53   S SD  . MET   A 1 85  ? 136.628 123.978 181.767 1.00 98.98  ? 74  MET   A SD  1 
ATOM   54   C CE  . MET   A 1 85  ? 136.079 122.309 182.114 1.00 101.51 ? 74  MET   A CE  1 
ATOM   55   N N   . ALA   A 1 86  ? 134.048 125.120 178.462 1.00 96.93  ? 75  ALA   A N   1 
ATOM   56   C CA  . ALA   A 1 86  ? 134.573 124.658 177.181 1.00 97.64  ? 75  ALA   A CA  1 
ATOM   57   C C   . ALA   A 1 86  ? 134.987 125.829 176.299 1.00 91.53  ? 75  ALA   A C   1 
ATOM   58   O O   . ALA   A 1 86  ? 136.032 125.779 175.637 1.00 86.71  ? 75  ALA   A O   1 
ATOM   59   C CB  . ALA   A 1 86  ? 133.535 123.789 176.472 1.00 102.76 ? 75  ALA   A CB  1 
ATOM   60   N N   . LEU   A 1 87  ? 134.175 126.889 176.271 1.00 92.79  ? 76  LEU   A N   1 
ATOM   61   C CA  . LEU   A 1 87  ? 134.540 128.076 175.503 1.00 91.10  ? 76  LEU   A CA  1 
ATOM   62   C C   . LEU   A 1 87  ? 135.829 128.693 176.028 1.00 89.30  ? 76  LEU   A C   1 
ATOM   63   O O   . LEU   A 1 87  ? 136.704 129.085 175.246 1.00 85.18  ? 76  LEU   A O   1 
ATOM   64   C CB  . LEU   A 1 87  ? 133.401 129.097 175.542 1.00 93.78  ? 76  LEU   A CB  1 
ATOM   65   C CG  . LEU   A 1 87  ? 133.770 130.557 175.262 1.00 90.69  ? 76  LEU   A CG  1 
ATOM   66   C CD1 . LEU   A 1 87  ? 134.117 130.758 173.795 1.00 91.85  ? 76  LEU   A CD1 1 
ATOM   67   C CD2 . LEU   A 1 87  ? 132.644 131.491 175.681 1.00 87.41  ? 76  LEU   A CD2 1 
ATOM   68   N N   . TYR   A 1 88  ? 135.964 128.783 177.353 1.00 91.87  ? 77  TYR   A N   1 
ATOM   69   C CA  . TYR   A 1 88  ? 137.178 129.335 177.940 1.00 89.03  ? 77  TYR   A CA  1 
ATOM   70   C C   . TYR   A 1 88  ? 138.389 128.479 177.600 1.00 84.93  ? 77  TYR   A C   1 
ATOM   71   O O   . TYR   A 1 88  ? 139.459 129.007 177.289 1.00 76.90  ? 77  TYR   A O   1 
ATOM   72   C CB  . TYR   A 1 88  ? 137.020 129.463 179.455 1.00 89.00  ? 77  TYR   A CB  1 
ATOM   73   C CG  . TYR   A 1 88  ? 136.789 130.880 179.929 1.00 82.82  ? 77  TYR   A CG  1 
ATOM   74   C CD1 . TYR   A 1 88  ? 135.817 131.677 179.341 1.00 84.72  ? 77  TYR   A CD1 1 
ATOM   75   C CD2 . TYR   A 1 88  ? 137.536 131.417 180.969 1.00 79.48  ? 77  TYR   A CD2 1 
ATOM   76   C CE1 . TYR   A 1 88  ? 135.599 132.970 179.770 1.00 83.41  ? 77  TYR   A CE1 1 
ATOM   77   C CE2 . TYR   A 1 88  ? 137.325 132.710 181.406 1.00 79.37  ? 77  TYR   A CE2 1 
ATOM   78   C CZ  . TYR   A 1 88  ? 136.355 133.481 180.803 1.00 76.12  ? 77  TYR   A CZ  1 
ATOM   79   O OH  . TYR   A 1 88  ? 136.137 134.769 181.232 1.00 69.46  ? 77  TYR   A OH  1 
ATOM   80   N N   . SER   A 1 89  ? 138.240 127.153 177.653 1.00 85.45  ? 78  SER   A N   1 
ATOM   81   C CA  . SER   A 1 89  ? 139.355 126.269 177.325 1.00 84.12  ? 78  SER   A CA  1 
ATOM   82   C C   . SER   A 1 89  ? 139.762 126.407 175.863 1.00 80.17  ? 78  SER   A C   1 
ATOM   83   O O   . SER   A 1 89  ? 140.959 126.437 175.544 1.00 73.66  ? 78  SER   A O   1 
ATOM   84   C CB  . SER   A 1 89  ? 138.987 124.820 177.645 1.00 86.74  ? 78  SER   A CB  1 
ATOM   85   O OG  . SER   A 1 89  ? 138.593 124.681 178.998 1.00 89.90  ? 78  SER   A OG  1 
ATOM   86   N N   . ILE   A 1 90  ? 138.780 126.494 174.961 1.00 79.33  ? 79  ILE   A N   1 
ATOM   87   C CA  . ILE   A 1 90  ? 139.085 126.655 173.541 1.00 72.06  ? 79  ILE   A CA  1 
ATOM   88   C C   . ILE   A 1 90  ? 139.804 127.976 173.302 1.00 71.88  ? 79  ILE   A C   1 
ATOM   89   O O   . ILE   A 1 90  ? 140.822 128.035 172.600 1.00 68.00  ? 79  ILE   A O   1 
ATOM   90   C CB  . ILE   A 1 90  ? 137.799 126.554 172.702 1.00 77.24  ? 79  ILE   A CB  1 
ATOM   91   N N   . VAL   A 1 91  ? 139.289 129.055 173.896 1.00 79.39  ? 80  VAL   A N   1 
ATOM   92   C CA  . VAL   A 1 91  ? 139.930 130.359 173.756 1.00 78.97  ? 80  VAL   A CA  1 
ATOM   93   C C   . VAL   A 1 91  ? 141.340 130.319 174.325 1.00 75.28  ? 80  VAL   A C   1 
ATOM   94   O O   . VAL   A 1 91  ? 142.272 130.878 173.744 1.00 70.30  ? 80  VAL   A O   1 
ATOM   95   C CB  . VAL   A 1 91  ? 139.081 131.451 174.433 1.00 74.18  ? 80  VAL   A CB  1 
ATOM   96   C CG1 . VAL   A 1 91  ? 139.879 132.739 174.566 1.00 66.28  ? 80  VAL   A CG1 1 
ATOM   97   C CG2 . VAL   A 1 91  ? 137.793 131.683 173.662 1.00 73.66  ? 80  VAL   A CG2 1 
ATOM   98   N N   . CYS   A 1 92  ? 141.525 129.637 175.454 1.00 73.90  ? 81  CYS   A N   1 
ATOM   99   C CA  . CYS   A 1 92  ? 142.840 129.583 176.079 1.00 71.03  ? 81  CYS   A CA  1 
ATOM   100  C C   . CYS   A 1 92  ? 143.845 128.880 175.180 1.00 72.77  ? 81  CYS   A C   1 
ATOM   101  O O   . CYS   A 1 92  ? 144.922 129.421 174.893 1.00 69.51  ? 81  CYS   A O   1 
ATOM   102  C CB  . CYS   A 1 92  ? 142.739 128.881 177.435 1.00 64.34  ? 81  CYS   A CB  1 
ATOM   103  S SG  . CYS   A 1 92  ? 144.261 128.098 178.000 1.00 51.07  ? 81  CYS   A SG  1 
ATOM   104  N N   . VAL   A 1 93  ? 143.502 127.673 174.717 1.00 72.68  ? 82  VAL   A N   1 
ATOM   105  C CA  . VAL   A 1 93  ? 144.441 126.902 173.904 1.00 71.15  ? 82  VAL   A CA  1 
ATOM   106  C C   . VAL   A 1 93  ? 144.738 127.631 172.598 1.00 66.00  ? 82  VAL   A C   1 
ATOM   107  O O   . VAL   A 1 93  ? 145.895 127.712 172.162 1.00 65.51  ? 82  VAL   A O   1 
ATOM   108  C CB  . VAL   A 1 93  ? 143.913 125.475 173.661 1.00 73.63  ? 82  VAL   A CB  1 
ATOM   109  C CG1 . VAL   A 1 93  ? 142.536 125.496 173.011 1.00 72.80  ? 82  VAL   A CG1 1 
ATOM   110  C CG2 . VAL   A 1 93  ? 144.891 124.689 172.797 1.00 76.56  ? 82  VAL   A CG2 1 
ATOM   111  N N   . VAL   A 1 94  ? 143.704 128.199 171.969 1.00 64.68  ? 83  VAL   A N   1 
ATOM   112  C CA  . VAL   A 1 94  ? 143.919 128.951 170.737 1.00 64.82  ? 83  VAL   A CA  1 
ATOM   113  C C   . VAL   A 1 94  ? 144.814 130.153 171.004 1.00 68.22  ? 83  VAL   A C   1 
ATOM   114  O O   . VAL   A 1 94  ? 145.690 130.486 170.199 1.00 69.50  ? 83  VAL   A O   1 
ATOM   115  C CB  . VAL   A 1 94  ? 142.572 129.367 170.120 1.00 63.16  ? 83  VAL   A CB  1 
ATOM   116  C CG1 . VAL   A 1 94  ? 142.789 130.349 168.991 1.00 61.42  ? 83  VAL   A CG1 1 
ATOM   117  C CG2 . VAL   A 1 94  ? 141.840 128.144 169.594 1.00 63.56  ? 83  VAL   A CG2 1 
ATOM   118  N N   . GLY   A 1 95  ? 144.616 130.817 172.144 1.00 67.49  ? 84  GLY   A N   1 
ATOM   119  C CA  . GLY   A 1 95  ? 145.419 131.985 172.452 1.00 66.94  ? 84  GLY   A CA  1 
ATOM   120  C C   . GLY   A 1 95  ? 146.885 131.650 172.633 1.00 69.70  ? 84  GLY   A C   1 
ATOM   121  O O   . GLY   A 1 95  ? 147.751 132.293 172.038 1.00 75.69  ? 84  GLY   A O   1 
ATOM   122  N N   . LEU   A 1 96  ? 147.184 130.618 173.430 1.00 63.27  ? 85  LEU   A N   1 
ATOM   123  C CA  . LEU   A 1 96  ? 148.585 130.233 173.590 1.00 66.74  ? 85  LEU   A CA  1 
ATOM   124  C C   . LEU   A 1 96  ? 149.189 129.815 172.259 1.00 69.18  ? 85  LEU   A C   1 
ATOM   125  O O   . LEU   A 1 96  ? 150.297 130.239 171.913 1.00 68.99  ? 85  LEU   A O   1 
ATOM   126  C CB  . LEU   A 1 96  ? 148.780 129.119 174.623 1.00 67.78  ? 85  LEU   A CB  1 
ATOM   127  C CG  . LEU   A 1 96  ? 148.264 129.171 176.062 1.00 56.71  ? 85  LEU   A CG  1 
ATOM   128  C CD1 . LEU   A 1 96  ? 147.206 128.129 176.276 1.00 56.74  ? 85  LEU   A CD1 1 
ATOM   129  C CD2 . LEU   A 1 96  ? 149.397 128.979 177.059 1.00 54.65  ? 85  LEU   A CD2 1 
ATOM   130  N N   . PHE   A 1 97  ? 148.469 128.994 171.487 1.00 68.43  ? 86  PHE   A N   1 
ATOM   131  C CA  . PHE   A 1 97  ? 149.012 128.529 170.215 1.00 70.04  ? 86  PHE   A CA  1 
ATOM   132  C C   . PHE   A 1 97  ? 149.310 129.696 169.279 1.00 76.16  ? 86  PHE   A C   1 
ATOM   133  O O   . PHE   A 1 97  ? 150.435 129.837 168.783 1.00 82.51  ? 86  PHE   A O   1 
ATOM   134  C CB  . PHE   A 1 97  ? 148.042 127.547 169.557 1.00 73.13  ? 86  PHE   A CB  1 
ATOM   135  N N   . GLY   A 1 98  ? 148.323 130.568 169.058 1.00 75.01  ? 87  GLY   A N   1 
ATOM   136  C CA  . GLY   A 1 98  ? 148.511 131.667 168.126 1.00 75.95  ? 87  GLY   A CA  1 
ATOM   137  C C   . GLY   A 1 98  ? 149.575 132.651 168.573 1.00 79.94  ? 87  GLY   A C   1 
ATOM   138  O O   . GLY   A 1 98  ? 150.405 133.086 167.771 1.00 85.69  ? 87  GLY   A O   1 
ATOM   139  N N   . ASN   A 1 99  ? 149.577 133.011 169.859 1.00 77.65  ? 88  ASN   A N   1 
ATOM   140  C CA  . ASN   A 1 99  ? 150.540 133.998 170.325 1.00 79.25  ? 88  ASN   A CA  1 
ATOM   141  C C   . ASN   A 1 99  ? 151.956 133.434 170.367 1.00 83.34  ? 88  ASN   A C   1 
ATOM   142  O O   . ASN   A 1 99  ? 152.914 134.151 170.055 1.00 84.81  ? 88  ASN   A O   1 
ATOM   143  C CB  . ASN   A 1 99  ? 150.111 134.525 171.690 1.00 73.91  ? 88  ASN   A CB  1 
ATOM   144  C CG  . ASN   A 1 99  ? 148.829 135.329 171.614 1.00 67.31  ? 88  ASN   A CG  1 
ATOM   145  O OD1 . ASN   A 1 99  ? 148.839 136.492 171.214 1.00 63.34  ? 88  ASN   A OD1 1 
ATOM   146  N ND2 . ASN   A 1 99  ? 147.715 134.710 171.992 1.00 66.36  ? 88  ASN   A ND2 1 
ATOM   147  N N   . PHE   A 1 100 ? 152.116 132.157 170.730 1.00 81.38  ? 89  PHE   A N   1 
ATOM   148  C CA  . PHE   A 1 100 ? 153.436 131.543 170.663 1.00 78.87  ? 89  PHE   A CA  1 
ATOM   149  C C   . PHE   A 1 100 ? 153.925 131.466 169.224 1.00 82.48  ? 89  PHE   A C   1 
ATOM   150  O O   . PHE   A 1 100 ? 155.109 131.695 168.949 1.00 86.35  ? 89  PHE   A O   1 
ATOM   151  C CB  . PHE   A 1 100 ? 153.398 130.153 171.298 1.00 77.99  ? 89  PHE   A CB  1 
ATOM   152  C CG  . PHE   A 1 100 ? 154.045 130.088 172.653 1.00 76.63  ? 89  PHE   A CG  1 
ATOM   153  C CD1 . PHE   A 1 100 ? 153.350 130.479 173.786 1.00 71.82  ? 89  PHE   A CD1 1 
ATOM   154  C CD2 . PHE   A 1 100 ? 155.348 129.641 172.794 1.00 78.55  ? 89  PHE   A CD2 1 
ATOM   155  C CE1 . PHE   A 1 100 ? 153.941 130.421 175.034 1.00 70.49  ? 89  PHE   A CE1 1 
ATOM   156  C CE2 . PHE   A 1 100 ? 155.945 129.582 174.040 1.00 76.38  ? 89  PHE   A CE2 1 
ATOM   157  C CZ  . PHE   A 1 100 ? 155.240 129.973 175.161 1.00 72.66  ? 89  PHE   A CZ  1 
ATOM   158  N N   . LEU   A 1 101 ? 153.023 131.152 168.288 1.00 83.74  ? 90  LEU   A N   1 
ATOM   159  C CA  . LEU   A 1 101 ? 153.392 131.150 166.876 1.00 86.63  ? 90  LEU   A CA  1 
ATOM   160  C C   . LEU   A 1 101 ? 153.836 132.536 166.421 1.00 91.25  ? 90  LEU   A C   1 
ATOM   161  O O   . LEU   A 1 101 ? 154.833 132.673 165.701 1.00 94.93  ? 90  LEU   A O   1 
ATOM   162  C CB  . LEU   A 1 101 ? 152.213 130.659 166.036 1.00 88.01  ? 90  LEU   A CB  1 
ATOM   163  C CG  . LEU   A 1 101 ? 152.249 130.894 164.526 1.00 95.79  ? 90  LEU   A CG  1 
ATOM   164  C CD1 . LEU   A 1 101 ? 153.419 130.161 163.890 1.00 104.74 ? 90  LEU   A CD1 1 
ATOM   165  C CD2 . LEU   A 1 101 ? 150.936 130.465 163.893 1.00 96.21  ? 90  LEU   A CD2 1 
ATOM   166  N N   . VAL   A 1 102 ? 153.104 133.574 166.832 1.00 90.85  ? 91  VAL   A N   1 
ATOM   167  C CA  . VAL   A 1 102 ? 153.462 134.941 166.457 1.00 91.98  ? 91  VAL   A CA  1 
ATOM   168  C C   . VAL   A 1 102 ? 154.835 135.300 167.014 1.00 94.94  ? 91  VAL   A C   1 
ATOM   169  O O   . VAL   A 1 102 ? 155.685 135.863 166.312 1.00 96.85  ? 91  VAL   A O   1 
ATOM   170  C CB  . VAL   A 1 102 ? 152.379 135.927 166.934 1.00 82.81  ? 91  VAL   A CB  1 
ATOM   171  C CG1 . VAL   A 1 102 ? 152.865 137.357 166.802 1.00 83.45  ? 91  VAL   A CG1 1 
ATOM   172  C CG2 . VAL   A 1 102 ? 151.097 135.734 166.142 1.00 74.71  ? 91  VAL   A CG2 1 
ATOM   173  N N   . MET   A 1 103 ? 155.076 134.965 168.284 1.00 91.83  ? 92  MET   A N   1 
ATOM   174  C CA  . MET   A 1 103 ? 156.371 135.255 168.889 1.00 93.42  ? 92  MET   A CA  1 
ATOM   175  C C   . MET   A 1 103 ? 157.495 134.529 168.160 1.00 98.54  ? 92  MET   A C   1 
ATOM   176  O O   . MET   A 1 103 ? 158.559 135.109 167.905 1.00 99.79  ? 92  MET   A O   1 
ATOM   177  C CB  . MET   A 1 103 ? 156.353 134.873 170.369 1.00 91.29  ? 92  MET   A CB  1 
ATOM   178  N N   . TYR   A 1 104 ? 157.275 133.258 167.810 1.00 99.50  ? 93  TYR   A N   1 
ATOM   179  C CA  . TYR   A 1 104 ? 158.312 132.493 167.128 1.00 99.98  ? 93  TYR   A CA  1 
ATOM   180  C C   . TYR   A 1 104 ? 158.609 133.063 165.747 1.00 99.09  ? 93  TYR   A C   1 
ATOM   181  O O   . TYR   A 1 104 ? 159.777 133.185 165.360 1.00 99.27  ? 93  TYR   A O   1 
ATOM   182  C CB  . TYR   A 1 104 ? 157.908 131.023 167.023 1.00 101.43 ? 93  TYR   A CB  1 
ATOM   183  C CG  . TYR   A 1 104 ? 158.853 130.203 166.173 1.00 106.91 ? 93  TYR   A CG  1 
ATOM   184  C CD1 . TYR   A 1 104 ? 160.080 129.784 166.671 1.00 107.12 ? 93  TYR   A CD1 1 
ATOM   185  C CD2 . TYR   A 1 104 ? 158.521 129.851 164.871 1.00 110.27 ? 93  TYR   A CD2 1 
ATOM   186  C CE1 . TYR   A 1 104 ? 160.949 129.038 165.898 1.00 109.75 ? 93  TYR   A CE1 1 
ATOM   187  C CE2 . TYR   A 1 104 ? 159.384 129.107 164.090 1.00 110.76 ? 93  TYR   A CE2 1 
ATOM   188  C CZ  . TYR   A 1 104 ? 160.595 128.702 164.608 1.00 109.91 ? 93  TYR   A CZ  1 
ATOM   189  O OH  . TYR   A 1 104 ? 161.456 127.958 163.834 1.00 105.91 ? 93  TYR   A OH  1 
ATOM   190  N N   . VAL   A 1 105 ? 157.571 133.412 164.983 1.00 97.99  ? 94  VAL   A N   1 
ATOM   191  C CA  . VAL   A 1 105 ? 157.809 133.933 163.639 1.00 99.77  ? 94  VAL   A CA  1 
ATOM   192  C C   . VAL   A 1 105 ? 158.452 135.314 163.703 1.00 101.49 ? 94  VAL   A C   1 
ATOM   193  O O   . VAL   A 1 105 ? 159.188 135.709 162.791 1.00 101.37 ? 94  VAL   A O   1 
ATOM   194  C CB  . VAL   A 1 105 ? 156.514 133.939 162.804 1.00 97.52  ? 94  VAL   A CB  1 
ATOM   195  C CG1 . VAL   A 1 105 ? 155.905 132.548 162.760 1.00 99.53  ? 94  VAL   A CG1 1 
ATOM   196  C CG2 . VAL   A 1 105 ? 155.516 134.951 163.338 1.00 92.55  ? 94  VAL   A CG2 1 
ATOM   197  N N   . ILE   A 1 106 ? 158.188 136.073 164.770 1.00 102.02 ? 95  ILE   A N   1 
ATOM   198  C CA  . ILE   A 1 106 ? 158.872 137.353 164.927 1.00 104.79 ? 95  ILE   A CA  1 
ATOM   199  C C   . ILE   A 1 106 ? 160.346 137.138 165.248 1.00 109.04 ? 95  ILE   A C   1 
ATOM   200  O O   . ILE   A 1 106 ? 161.224 137.793 164.672 1.00 108.94 ? 95  ILE   A O   1 
ATOM   201  C CB  . ILE   A 1 106 ? 158.176 138.209 166.000 1.00 97.64  ? 95  ILE   A CB  1 
ATOM   202  C CG1 . ILE   A 1 106 ? 156.840 138.730 165.474 1.00 90.73  ? 95  ILE   A CG1 1 
ATOM   203  C CG2 . ILE   A 1 106 ? 159.066 139.368 166.424 1.00 93.01  ? 95  ILE   A CG2 1 
ATOM   204  C CD1 . ILE   A 1 106 ? 155.931 139.244 166.555 1.00 87.29  ? 95  ILE   A CD1 1 
ATOM   205  N N   . VAL   A 1 107 ? 160.647 136.213 166.162 1.00 106.24 ? 96  VAL   A N   1 
ATOM   206  C CA  . VAL   A 1 107 ? 162.034 135.997 166.562 1.00 106.61 ? 96  VAL   A CA  1 
ATOM   207  C C   . VAL   A 1 107 ? 162.808 135.138 165.569 1.00 109.43 ? 96  VAL   A C   1 
ATOM   208  O O   . VAL   A 1 107 ? 164.018 134.945 165.742 1.00 112.26 ? 96  VAL   A O   1 
ATOM   209  C CB  . VAL   A 1 107 ? 162.102 135.359 167.959 1.00 101.79 ? 96  VAL   A CB  1 
ATOM   210  N N   . ARG   A 1 108 ? 162.146 134.613 164.535 1.00 110.52 ? 97  ARG   A N   1 
ATOM   211  C CA  . ARG   A 1 108 ? 162.797 133.661 163.639 1.00 112.61 ? 97  ARG   A CA  1 
ATOM   212  C C   . ARG   A 1 108 ? 163.866 134.327 162.780 1.00 111.02 ? 97  ARG   A C   1 
ATOM   213  O O   . ARG   A 1 108 ? 164.993 133.828 162.675 1.00 110.14 ? 97  ARG   A O   1 
ATOM   214  C CB  . ARG   A 1 108 ? 161.750 132.978 162.758 1.00 112.90 ? 97  ARG   A CB  1 
ATOM   215  N N   . TYR   A 1 109 ? 163.537 135.458 162.158 1.00 110.81 ? 98  TYR   A N   1 
ATOM   216  C CA  . TYR   A 1 109 ? 164.391 136.052 161.140 1.00 114.15 ? 98  TYR   A CA  1 
ATOM   217  C C   . TYR   A 1 109 ? 164.731 137.492 161.492 1.00 112.44 ? 98  TYR   A C   1 
ATOM   218  O O   . TYR   A 1 109 ? 163.969 138.181 162.176 1.00 109.03 ? 98  TYR   A O   1 
ATOM   219  C CB  . TYR   A 1 109 ? 163.724 136.004 159.757 1.00 113.83 ? 98  TYR   A CB  1 
ATOM   220  N N   . THR   A 1 110 ? 165.895 137.937 161.011 1.00 114.81 ? 99  THR   A N   1 
ATOM   221  C CA  . THR   A 1 110 ? 166.317 139.319 161.211 1.00 116.31 ? 99  THR   A CA  1 
ATOM   222  C C   . THR   A 1 110 ? 165.503 140.292 160.368 1.00 112.51 ? 99  THR   A C   1 
ATOM   223  O O   . THR   A 1 110 ? 165.370 141.464 160.738 1.00 108.78 ? 99  THR   A O   1 
ATOM   224  C CB  . THR   A 1 110 ? 167.805 139.470 160.889 1.00 118.18 ? 99  THR   A CB  1 
ATOM   225  N N   . LYS   A 1 111 ? 164.963 139.835 159.235 1.00 111.38 ? 100 LYS   A N   1 
ATOM   226  C CA  . LYS   A 1 111 ? 164.065 140.676 158.452 1.00 109.07 ? 100 LYS   A CA  1 
ATOM   227  C C   . LYS   A 1 111 ? 162.751 140.925 159.176 1.00 106.70 ? 100 LYS   A C   1 
ATOM   228  O O   . LYS   A 1 111 ? 162.021 141.856 158.817 1.00 105.36 ? 100 LYS   A O   1 
ATOM   229  C CB  . LYS   A 1 111 ? 163.800 140.038 157.087 1.00 111.08 ? 100 LYS   A CB  1 
ATOM   230  N N   . MET   A 1 112 ? 162.434 140.112 160.184 1.00 106.69 ? 101 MET   A N   1 
ATOM   231  C CA  . MET   A 1 112 ? 161.270 140.311 161.034 1.00 105.63 ? 101 MET   A CA  1 
ATOM   232  C C   . MET   A 1 112 ? 161.611 141.089 162.300 1.00 108.92 ? 101 MET   A C   1 
ATOM   233  O O   . MET   A 1 112 ? 160.942 140.917 163.325 1.00 109.85 ? 101 MET   A O   1 
ATOM   234  C CB  . MET   A 1 112 ? 160.647 138.963 161.398 1.00 107.06 ? 101 MET   A CB  1 
ATOM   235  C CG  . MET   A 1 112 ? 159.789 138.354 160.304 1.00 105.12 ? 101 MET   A CG  1 
ATOM   236  S SD  . MET   A 1 112 ? 158.681 139.549 159.536 1.00 98.49  ? 101 MET   A SD  1 
ATOM   237  C CE  . MET   A 1 112 ? 157.351 138.472 159.011 1.00 81.18  ? 101 MET   A CE  1 
ATOM   238  N N   . LYS   A 1 113 ? 162.641 141.935 162.251 1.00 107.68 ? 102 LYS   A N   1 
ATOM   239  C CA  . LYS   A 1 113 ? 163.095 142.693 163.410 1.00 105.00 ? 102 LYS   A CA  1 
ATOM   240  C C   . LYS   A 1 113 ? 162.942 144.198 163.217 1.00 101.71 ? 102 LYS   A C   1 
ATOM   241  O O   . LYS   A 1 113 ? 163.753 144.976 163.730 1.00 104.74 ? 102 LYS   A O   1 
ATOM   242  C CB  . LYS   A 1 113 ? 164.548 142.346 163.733 1.00 106.10 ? 102 LYS   A CB  1 
ATOM   243  N N   . THR   A 1 114 ? 161.918 144.626 162.483 1.00 97.78  ? 103 THR   A N   1 
ATOM   244  C CA  . THR   A 1 114 ? 161.653 146.048 162.344 1.00 96.75  ? 103 THR   A CA  1 
ATOM   245  C C   . THR   A 1 114 ? 161.055 146.599 163.638 1.00 94.64  ? 103 THR   A C   1 
ATOM   246  O O   . THR   A 1 114 ? 160.687 145.856 164.551 1.00 91.98  ? 103 THR   A O   1 
ATOM   247  C CB  . THR   A 1 114 ? 160.717 146.312 161.165 1.00 94.89  ? 103 THR   A CB  1 
ATOM   248  O OG1 . THR   A 1 114 ? 159.530 145.522 161.307 1.00 92.81  ? 103 THR   A OG1 1 
ATOM   249  C CG2 . THR   A 1 114 ? 161.399 145.957 159.852 1.00 97.18  ? 103 THR   A CG2 1 
ATOM   250  N N   . ALA   A 1 115 ? 160.963 147.930 163.707 1.00 90.02  ? 104 ALA   A N   1 
ATOM   251  C CA  . ALA   A 1 115 ? 160.486 148.579 164.925 1.00 85.18  ? 104 ALA   A CA  1 
ATOM   252  C C   . ALA   A 1 115 ? 159.062 148.154 165.262 1.00 81.27  ? 104 ALA   A C   1 
ATOM   253  O O   . ALA   A 1 115 ? 158.737 147.922 166.432 1.00 80.66  ? 104 ALA   A O   1 
ATOM   254  C CB  . ALA   A 1 115 ? 160.572 150.098 164.777 1.00 74.90  ? 104 ALA   A CB  1 
ATOM   255  N N   . THR   A 1 116 ? 158.200 148.048 164.250 1.00 77.37  ? 105 THR   A N   1 
ATOM   256  C CA  . THR   A 1 116 ? 156.826 147.617 164.484 1.00 70.49  ? 105 THR   A CA  1 
ATOM   257  C C   . THR   A 1 116 ? 156.775 146.179 164.991 1.00 74.46  ? 105 THR   A C   1 
ATOM   258  O O   . THR   A 1 116 ? 155.965 145.845 165.867 1.00 76.27  ? 105 THR   A O   1 
ATOM   259  C CB  . THR   A 1 116 ? 156.015 147.776 163.195 1.00 66.05  ? 105 THR   A CB  1 
ATOM   260  O OG1 . THR   A 1 116 ? 155.607 149.142 163.054 1.00 58.61  ? 105 THR   A OG1 1 
ATOM   261  C CG2 . THR   A 1 116 ? 154.782 146.893 163.209 1.00 64.12  ? 105 THR   A CG2 1 
ATOM   262  N N   . ASN   A 1 117 ? 157.643 145.314 164.459 1.00 78.32  ? 106 ASN   A N   1 
ATOM   263  C CA  . ASN   A 1 117 ? 157.614 143.908 164.846 1.00 78.82  ? 106 ASN   A CA  1 
ATOM   264  C C   . ASN   A 1 117 ? 158.012 143.704 166.301 1.00 76.78  ? 106 ASN   A C   1 
ATOM   265  O O   . ASN   A 1 117 ? 157.540 142.760 166.938 1.00 74.22  ? 106 ASN   A O   1 
ATOM   266  C CB  . ASN   A 1 117 ? 158.518 143.088 163.926 1.00 87.84  ? 106 ASN   A CB  1 
ATOM   267  C CG  . ASN   A 1 117 ? 158.109 143.188 162.472 1.00 91.63  ? 106 ASN   A CG  1 
ATOM   268  O OD1 . ASN   A 1 117 ? 157.438 144.136 162.068 1.00 89.07  ? 106 ASN   A OD1 1 
ATOM   269  N ND2 . ASN   A 1 117 ? 158.510 142.205 161.675 1.00 96.04  ? 106 ASN   A ND2 1 
ATOM   270  N N   . ILE   A 1 118 ? 158.868 144.568 166.851 1.00 76.36  ? 107 ILE   A N   1 
ATOM   271  C CA  . ILE   A 1 118 ? 159.242 144.438 168.259 1.00 79.15  ? 107 ILE   A CA  1 
ATOM   272  C C   . ILE   A 1 118 ? 158.035 144.692 169.157 1.00 74.37  ? 107 ILE   A C   1 
ATOM   273  O O   . ILE   A 1 118 ? 157.799 143.973 170.137 1.00 70.11  ? 107 ILE   A O   1 
ATOM   274  C CB  . ILE   A 1 118 ? 160.412 145.379 168.597 1.00 79.16  ? 107 ILE   A CB  1 
ATOM   275  C CG1 . ILE   A 1 118 ? 161.503 145.264 167.531 1.00 80.38  ? 107 ILE   A CG1 1 
ATOM   276  C CG2 . ILE   A 1 118 ? 160.973 145.060 169.973 1.00 86.56  ? 107 ILE   A CG2 1 
ATOM   277  C CD1 . ILE   A 1 118 ? 162.671 146.193 167.742 1.00 89.99  ? 107 ILE   A CD1 1 
ATOM   278  N N   . TYR   A 1 119 ? 157.247 145.716 168.833 1.00 71.74  ? 108 TYR   A N   1 
ATOM   279  C CA  . TYR   A 1 119 ? 156.039 145.970 169.606 1.00 67.12  ? 108 TYR   A CA  1 
ATOM   280  C C   . TYR   A 1 119 ? 154.978 144.900 169.370 1.00 65.08  ? 108 TYR   A C   1 
ATOM   281  O O   . TYR   A 1 119 ? 154.227 144.568 170.294 1.00 62.91  ? 108 TYR   A O   1 
ATOM   282  C CB  . TYR   A 1 119 ? 155.496 147.363 169.288 1.00 58.56  ? 108 TYR   A CB  1 
ATOM   283  C CG  . TYR   A 1 119 ? 156.552 148.445 169.360 1.00 57.77  ? 108 TYR   A CG  1 
ATOM   284  C CD1 . TYR   A 1 119 ? 157.445 148.498 170.421 1.00 58.69  ? 108 TYR   A CD1 1 
ATOM   285  C CD2 . TYR   A 1 119 ? 156.660 149.407 168.366 1.00 58.13  ? 108 TYR   A CD2 1 
ATOM   286  C CE1 . TYR   A 1 119 ? 158.414 149.480 170.491 1.00 68.92  ? 108 TYR   A CE1 1 
ATOM   287  C CE2 . TYR   A 1 119 ? 157.624 150.393 168.427 1.00 58.46  ? 108 TYR   A CE2 1 
ATOM   288  C CZ  . TYR   A 1 119 ? 158.498 150.425 169.491 1.00 68.81  ? 108 TYR   A CZ  1 
ATOM   289  O OH  . TYR   A 1 119 ? 159.460 151.407 169.554 1.00 75.48  ? 108 TYR   A OH  1 
ATOM   290  N N   . ILE   A 1 120 ? 154.905 144.339 168.161 1.00 63.37  ? 109 ILE   A N   1 
ATOM   291  C CA  . ILE   A 1 120 ? 154.022 143.191 167.954 1.00 66.12  ? 109 ILE   A CA  1 
ATOM   292  C C   . ILE   A 1 120 ? 154.461 142.026 168.833 1.00 68.87  ? 109 ILE   A C   1 
ATOM   293  O O   . ILE   A 1 120 ? 153.632 141.311 169.410 1.00 66.01  ? 109 ILE   A O   1 
ATOM   294  C CB  . ILE   A 1 120 ? 153.975 142.795 166.466 1.00 67.48  ? 109 ILE   A CB  1 
ATOM   295  C CG1 . ILE   A 1 120 ? 153.385 143.925 165.626 1.00 65.43  ? 109 ILE   A CG1 1 
ATOM   296  C CG2 . ILE   A 1 120 ? 153.146 141.537 166.275 1.00 63.33  ? 109 ILE   A CG2 1 
ATOM   297  C CD1 . ILE   A 1 120 ? 153.510 143.694 164.141 1.00 65.22  ? 109 ILE   A CD1 1 
ATOM   298  N N   . PHE   A 1 121 ? 155.775 141.826 168.954 1.00 73.17  ? 110 PHE   A N   1 
ATOM   299  C CA  . PHE   A 1 121 ? 156.315 140.805 169.845 1.00 74.08  ? 110 PHE   A CA  1 
ATOM   300  C C   . PHE   A 1 121 ? 155.896 141.055 171.285 1.00 69.50  ? 110 PHE   A C   1 
ATOM   301  O O   . PHE   A 1 121 ? 155.506 140.127 171.999 1.00 64.31  ? 110 PHE   A O   1 
ATOM   302  C CB  . PHE   A 1 121 ? 157.840 140.775 169.731 1.00 77.67  ? 110 PHE   A CB  1 
ATOM   303  C CG  . PHE   A 1 121 ? 158.478 139.566 170.355 1.00 84.52  ? 110 PHE   A CG  1 
ATOM   304  C CD1 . PHE   A 1 121 ? 158.347 138.314 169.779 1.00 86.53  ? 110 PHE   A CD1 1 
ATOM   305  C CD2 . PHE   A 1 121 ? 159.221 139.688 171.518 1.00 82.90  ? 110 PHE   A CD2 1 
ATOM   306  C CE1 . PHE   A 1 121 ? 158.942 137.207 170.355 1.00 84.49  ? 110 PHE   A CE1 1 
ATOM   307  C CE2 . PHE   A 1 121 ? 159.815 138.584 172.098 1.00 82.21  ? 110 PHE   A CE2 1 
ATOM   308  C CZ  . PHE   A 1 121 ? 159.674 137.342 171.516 1.00 84.35  ? 110 PHE   A CZ  1 
ATOM   309  N N   . ASN   A 1 122 ? 155.986 142.308 171.735 1.00 70.92  ? 111 ASN   A N   1 
ATOM   310  C CA  . ASN   A 1 122 ? 155.611 142.619 173.113 1.00 66.55  ? 111 ASN   A CA  1 
ATOM   311  C C   . ASN   A 1 122 ? 154.121 142.394 173.352 1.00 61.27  ? 111 ASN   A C   1 
ATOM   312  O O   . ASN   A 1 122 ? 153.725 141.868 174.400 1.00 62.61  ? 111 ASN   A O   1 
ATOM   313  C CB  . ASN   A 1 122 ? 155.995 144.056 173.459 1.00 63.53  ? 111 ASN   A CB  1 
ATOM   314  C CG  . ASN   A 1 122 ? 155.832 144.359 174.935 1.00 63.55  ? 111 ASN   A CG  1 
ATOM   315  O OD1 . ASN   A 1 122 ? 156.532 143.796 175.776 1.00 73.89  ? 111 ASN   A OD1 1 
ATOM   316  N ND2 . ASN   A 1 122 ? 154.902 145.247 175.258 1.00 52.63  ? 111 ASN   A ND2 1 
ATOM   317  N N   . LEU   A 1 123 ? 153.280 142.792 172.396 1.00 55.55  ? 112 LEU   A N   1 
ATOM   318  C CA  . LEU   A 1 123 ? 151.842 142.576 172.534 1.00 55.44  ? 112 LEU   A CA  1 
ATOM   319  C C   . LEU   A 1 123 ? 151.514 141.087 172.571 1.00 59.92  ? 112 LEU   A C   1 
ATOM   320  O O   . LEU   A 1 123 ? 150.689 140.639 173.377 1.00 58.63  ? 112 LEU   A O   1 
ATOM   321  C CB  . LEU   A 1 123 ? 151.100 143.273 171.393 1.00 46.93  ? 112 LEU   A CB  1 
ATOM   322  C CG  . LEU   A 1 123 ? 149.594 143.043 171.251 1.00 41.11  ? 112 LEU   A CG  1 
ATOM   323  C CD1 . LEU   A 1 123 ? 148.871 143.258 172.570 1.00 38.33  ? 112 LEU   A CD1 1 
ATOM   324  C CD2 . LEU   A 1 123 ? 149.027 143.961 170.183 1.00 40.75  ? 112 LEU   A CD2 1 
ATOM   325  N N   . ALA   A 1 124 ? 152.159 140.300 171.706 1.00 64.11  ? 113 ALA   A N   1 
ATOM   326  C CA  . ALA   A 1 124 ? 151.947 138.856 171.720 1.00 60.95  ? 113 ALA   A CA  1 
ATOM   327  C C   . ALA   A 1 124 ? 152.448 138.237 173.018 1.00 60.59  ? 113 ALA   A C   1 
ATOM   328  O O   . ALA   A 1 124 ? 151.846 137.289 173.531 1.00 61.34  ? 113 ALA   A O   1 
ATOM   329  C CB  . ALA   A 1 124 ? 152.632 138.211 170.516 1.00 71.72  ? 113 ALA   A CB  1 
ATOM   330  N N   . LEU   A 1 125 ? 153.556 138.751 173.553 1.00 63.21  ? 114 LEU   A N   1 
ATOM   331  C CA  . LEU   A 1 125 ? 154.071 138.273 174.831 1.00 67.25  ? 114 LEU   A CA  1 
ATOM   332  C C   . LEU   A 1 125 ? 153.066 138.529 175.948 1.00 63.74  ? 114 LEU   A C   1 
ATOM   333  O O   . LEU   A 1 125 ? 152.798 137.651 176.778 1.00 62.73  ? 114 LEU   A O   1 
ATOM   334  C CB  . LEU   A 1 125 ? 155.407 138.963 175.122 1.00 70.42  ? 114 LEU   A CB  1 
ATOM   335  C CG  . LEU   A 1 125 ? 156.514 138.297 175.944 1.00 73.57  ? 114 LEU   A CG  1 
ATOM   336  C CD1 . LEU   A 1 125 ? 157.730 139.208 175.992 1.00 66.81  ? 114 LEU   A CD1 1 
ATOM   337  C CD2 . LEU   A 1 125 ? 156.060 137.972 177.352 1.00 71.42  ? 114 LEU   A CD2 1 
ATOM   338  N N   . ALA   A 1 126 ? 152.493 139.734 175.974 1.00 59.08  ? 115 ALA   A N   1 
ATOM   339  C CA  . ALA   A 1 126 ? 151.487 140.055 176.980 1.00 58.05  ? 115 ALA   A CA  1 
ATOM   340  C C   . ALA   A 1 126 ? 150.255 139.172 176.830 1.00 53.36  ? 115 ALA   A C   1 
ATOM   341  O O   . ALA   A 1 126 ? 149.692 138.703 177.825 1.00 53.25  ? 115 ALA   A O   1 
ATOM   342  C CB  . ALA   A 1 126 ? 151.104 141.531 176.890 1.00 53.58  ? 115 ALA   A CB  1 
ATOM   343  N N   . ASP   A 1 127 ? 149.821 138.933 175.590 1.00 50.17  ? 116 ASP   A N   1 
ATOM   344  C CA  . ASP   A 1 127 ? 148.664 138.072 175.367 1.00 51.25  ? 116 ASP   A CA  1 
ATOM   345  C C   . ASP   A 1 127 ? 148.941 136.641 175.812 1.00 56.72  ? 116 ASP   A C   1 
ATOM   346  O O   . ASP   A 1 127 ? 148.079 135.992 176.417 1.00 56.86  ? 116 ASP   A O   1 
ATOM   347  C CB  . ASP   A 1 127 ? 148.264 138.105 173.894 1.00 58.17  ? 116 ASP   A CB  1 
ATOM   348  C CG  . ASP   A 1 127 ? 147.328 139.246 173.574 1.00 61.11  ? 116 ASP   A CG  1 
ATOM   349  O OD1 . ASP   A 1 127 ? 146.678 139.758 174.509 1.00 62.00  ? 116 ASP   A OD1 1 
ATOM   350  O OD2 . ASP   A 1 127 ? 147.236 139.628 172.389 1.00 58.12  ? 116 ASP   A OD2 1 
ATOM   351  N N   . ALA   A 1 128 ? 150.137 136.128 175.515 1.00 61.32  ? 117 ALA   A N   1 
ATOM   352  C CA  . ALA   A 1 128 ? 150.495 134.779 175.938 1.00 57.97  ? 117 ALA   A CA  1 
ATOM   353  C C   . ALA   A 1 128 ? 150.532 134.673 177.456 1.00 51.38  ? 117 ALA   A C   1 
ATOM   354  O O   . ALA   A 1 128 ? 150.073 133.677 178.028 1.00 47.68  ? 117 ALA   A O   1 
ATOM   355  C CB  . ALA   A 1 128 ? 151.842 134.379 175.338 1.00 63.37  ? 117 ALA   A CB  1 
ATOM   356  N N   . LEU   A 1 129 ? 151.074 135.693 178.125 1.00 51.08  ? 118 LEU   A N   1 
ATOM   357  C CA  . LEU   A 1 129 ? 151.094 135.689 179.584 1.00 53.44  ? 118 LEU   A CA  1 
ATOM   358  C C   . LEU   A 1 129 ? 149.684 135.758 180.158 1.00 53.48  ? 118 LEU   A C   1 
ATOM   359  O O   . LEU   A 1 129 ? 149.386 135.111 181.169 1.00 56.32  ? 118 LEU   A O   1 
ATOM   360  C CB  . LEU   A 1 129 ? 151.950 136.846 180.097 1.00 48.78  ? 118 LEU   A CB  1 
ATOM   361  C CG  . LEU   A 1 129 ? 153.382 136.475 180.491 1.00 49.34  ? 118 LEU   A CG  1 
ATOM   362  C CD1 . LEU   A 1 129 ? 154.097 135.791 179.341 1.00 56.82  ? 118 LEU   A CD1 1 
ATOM   363  C CD2 . LEU   A 1 129 ? 154.152 137.708 180.934 1.00 43.86  ? 118 LEU   A CD2 1 
ATOM   364  N N   . ALA   A 1 130 ? 148.801 136.536 179.530 1.00 50.32  ? 119 ALA   A N   1 
ATOM   365  C CA  . ALA   A 1 130 ? 147.436 136.653 180.028 1.00 44.18  ? 119 ALA   A CA  1 
ATOM   366  C C   . ALA   A 1 130 ? 146.581 135.440 179.689 1.00 44.33  ? 119 ALA   A C   1 
ATOM   367  O O   . ALA   A 1 130 ? 145.516 135.266 180.290 1.00 47.12  ? 119 ALA   A O   1 
ATOM   368  C CB  . ALA   A 1 130 ? 146.777 137.913 179.473 1.00 50.76  ? 119 ALA   A CB  1 
ATOM   369  N N   . THR   A 1 131 ? 147.010 134.609 178.739 1.00 48.51  ? 120 THR   A N   1 
ATOM   370  C CA  . THR   A 1 131 ? 146.261 133.408 178.390 1.00 51.58  ? 120 THR   A CA  1 
ATOM   371  C C   . THR   A 1 131 ? 146.721 132.173 179.151 1.00 51.94  ? 120 THR   A C   1 
ATOM   372  O O   . THR   A 1 131 ? 145.928 131.240 179.324 1.00 51.01  ? 120 THR   A O   1 
ATOM   373  C CB  . THR   A 1 131 ? 146.361 133.127 176.888 1.00 51.18  ? 120 THR   A CB  1 
ATOM   374  O OG1 . THR   A 1 131 ? 147.654 133.512 176.411 1.00 50.06  ? 120 THR   A OG1 1 
ATOM   375  C CG2 . THR   A 1 131 ? 145.295 133.893 176.130 1.00 52.26  ? 120 THR   A CG2 1 
ATOM   376  N N   . SER   A 1 132 ? 147.975 132.143 179.606 1.00 51.49  ? 121 SER   A N   1 
ATOM   377  C CA  . SER   A 1 132 ? 148.480 130.978 180.322 1.00 49.61  ? 121 SER   A CA  1 
ATOM   378  C C   . SER   A 1 132 ? 147.739 130.737 181.630 1.00 51.35  ? 121 SER   A C   1 
ATOM   379  O O   . SER   A 1 132 ? 147.730 129.605 182.123 1.00 61.35  ? 121 SER   A O   1 
ATOM   380  C CB  . SER   A 1 132 ? 149.977 131.135 180.593 1.00 48.75  ? 121 SER   A CB  1 
ATOM   381  O OG  . SER   A 1 132 ? 150.213 132.070 181.630 1.00 50.50  ? 121 SER   A OG  1 
ATOM   382  N N   . THR   A 1 133 ? 147.120 131.767 182.200 1.00 50.99  ? 122 THR   A N   1 
ATOM   383  C CA  . THR   A 1 133 ? 146.394 131.639 183.456 1.00 61.10  ? 122 THR   A CA  1 
ATOM   384  C C   . THR   A 1 133 ? 144.914 131.340 183.259 1.00 60.87  ? 122 THR   A C   1 
ATOM   385  O O   . THR   A 1 133 ? 144.180 131.243 184.247 1.00 64.38  ? 122 THR   A O   1 
ATOM   386  C CB  . THR   A 1 133 ? 146.553 132.914 184.288 1.00 62.04  ? 122 THR   A CB  1 
ATOM   387  O OG1 . THR   A 1 133 ? 145.776 133.968 183.706 1.00 58.54  ? 122 THR   A OG1 1 
ATOM   388  C CG2 . THR   A 1 133 ? 148.014 133.332 184.340 1.00 59.90  ? 122 THR   A CG2 1 
ATOM   389  N N   . LEU   A 1 134 ? 144.461 131.206 182.014 1.00 52.16  ? 123 LEU   A N   1 
ATOM   390  C CA  . LEU   A 1 134 ? 143.062 130.878 181.770 1.00 56.38  ? 123 LEU   A CA  1 
ATOM   391  C C   . LEU   A 1 134 ? 142.612 129.523 182.320 1.00 66.32  ? 123 LEU   A C   1 
ATOM   392  O O   . LEU   A 1 134 ? 141.496 129.469 182.865 1.00 72.04  ? 123 LEU   A O   1 
ATOM   393  C CB  . LEU   A 1 134 ? 142.772 130.970 180.266 1.00 55.58  ? 123 LEU   A CB  1 
ATOM   394  C CG  . LEU   A 1 134 ? 142.428 132.374 179.770 1.00 51.53  ? 123 LEU   A CG  1 
ATOM   395  C CD1 . LEU   A 1 134 ? 142.658 132.501 178.277 1.00 53.50  ? 123 LEU   A CD1 1 
ATOM   396  C CD2 . LEU   A 1 134 ? 140.988 132.702 180.119 1.00 52.58  ? 123 LEU   A CD2 1 
ATOM   397  N N   . PRO   A 1 135 ? 143.360 128.415 182.185 1.00 64.64  ? 124 PRO   A N   1 
ATOM   398  C CA  . PRO   A 1 135 ? 142.842 127.144 182.726 1.00 63.87  ? 124 PRO   A CA  1 
ATOM   399  C C   . PRO   A 1 135 ? 142.617 127.166 184.228 1.00 69.07  ? 124 PRO   A C   1 
ATOM   400  O O   . PRO   A 1 135 ? 141.663 126.543 184.713 1.00 69.93  ? 124 PRO   A O   1 
ATOM   401  C CB  . PRO   A 1 135 ? 143.913 126.127 182.313 1.00 59.07  ? 124 PRO   A CB  1 
ATOM   402  C CG  . PRO   A 1 135 ? 145.153 126.910 182.200 1.00 57.81  ? 124 PRO   A CG  1 
ATOM   403  C CD  . PRO   A 1 135 ? 144.741 128.262 181.688 1.00 63.53  ? 124 PRO   A CD  1 
ATOM   404  N N   . PHE   A 1 136 ? 143.468 127.865 184.985 1.00 69.23  ? 125 PHE   A N   1 
ATOM   405  C CA  . PHE   A 1 136 ? 143.228 128.002 186.418 1.00 71.96  ? 125 PHE   A CA  1 
ATOM   406  C C   . PHE   A 1 136 ? 141.954 128.792 186.686 1.00 73.32  ? 125 PHE   A C   1 
ATOM   407  O O   . PHE   A 1 136 ? 141.164 128.432 187.567 1.00 76.82  ? 125 PHE   A O   1 
ATOM   408  C CB  . PHE   A 1 136 ? 144.418 128.672 187.116 1.00 74.17  ? 125 PHE   A CB  1 
ATOM   409  C CG  . PHE   A 1 136 ? 145.771 128.221 186.623 1.00 73.16  ? 125 PHE   A CG  1 
ATOM   410  C CD1 . PHE   A 1 136 ? 146.279 128.661 185.411 1.00 63.94  ? 125 PHE   A CD1 1 
ATOM   411  C CD2 . PHE   A 1 136 ? 146.562 127.405 187.413 1.00 78.46  ? 125 PHE   A CD2 1 
ATOM   412  C CE1 . PHE   A 1 136 ? 147.526 128.256 184.976 1.00 62.91  ? 125 PHE   A CE1 1 
ATOM   413  C CE2 . PHE   A 1 136 ? 147.810 126.998 186.983 1.00 79.71  ? 125 PHE   A CE2 1 
ATOM   414  C CZ  . PHE   A 1 136 ? 148.294 127.426 185.765 1.00 71.56  ? 125 PHE   A CZ  1 
ATOM   415  N N   . GLN   A 1 137 ? 141.737 129.873 185.935 1.00 69.04  ? 126 GLN   A N   1 
ATOM   416  C CA  . GLN   A 1 137 ? 140.559 130.708 186.137 1.00 71.88  ? 126 GLN   A CA  1 
ATOM   417  C C   . GLN   A 1 137 ? 139.271 130.010 185.723 1.00 79.68  ? 126 GLN   A C   1 
ATOM   418  O O   . GLN   A 1 137 ? 138.211 130.308 186.283 1.00 83.05  ? 126 GLN   A O   1 
ATOM   419  C CB  . GLN   A 1 137 ? 140.707 132.016 185.361 1.00 68.20  ? 126 GLN   A CB  1 
ATOM   420  C CG  . GLN   A 1 137 ? 141.720 132.981 185.950 1.00 66.72  ? 126 GLN   A CG  1 
ATOM   421  C CD  . GLN   A 1 137 ? 142.345 133.871 184.897 1.00 62.12  ? 126 GLN   A CD  1 
ATOM   422  O OE1 . GLN   A 1 137 ? 142.357 133.535 183.714 1.00 64.29  ? 126 GLN   A OE1 1 
ATOM   423  N NE2 . GLN   A 1 137 ? 142.861 135.017 185.321 1.00 59.71  ? 126 GLN   A NE2 1 
ATOM   424  N N   . SER   A 1 138 ? 139.336 129.095 184.756 1.00 82.72  ? 127 SER   A N   1 
ATOM   425  C CA  . SER   A 1 138 ? 138.152 128.396 184.274 1.00 86.67  ? 127 SER   A CA  1 
ATOM   426  C C   . SER   A 1 138 ? 137.803 127.168 185.101 1.00 89.39  ? 127 SER   A C   1 
ATOM   427  O O   . SER   A 1 138 ? 136.632 126.778 185.144 1.00 93.64  ? 127 SER   A O   1 
ATOM   428  C CB  . SER   A 1 138 ? 138.341 127.979 182.812 1.00 81.75  ? 127 SER   A CB  1 
ATOM   429  O OG  . SER   A 1 138 ? 139.556 127.272 182.637 1.00 76.68  ? 127 SER   A OG  1 
ATOM   430  N N   . VAL   A 1 139 ? 138.790 126.551 185.754 1.00 86.36  ? 128 VAL   A N   1 
ATOM   431  C CA  . VAL   A 1 139 ? 138.526 125.404 186.613 1.00 90.35  ? 128 VAL   A CA  1 
ATOM   432  C C   . VAL   A 1 139 ? 137.683 125.792 187.816 1.00 93.93  ? 128 VAL   A C   1 
ATOM   433  O O   . VAL   A 1 139 ? 136.858 124.996 188.276 1.00 97.89  ? 128 VAL   A O   1 
ATOM   434  C CB  . VAL   A 1 139 ? 139.851 124.753 187.061 1.00 90.08  ? 128 VAL   A CB  1 
ATOM   435  N N   . ASN   A 1 140 ? 137.869 127.008 188.339 1.00 90.35  ? 129 ASN   A N   1 
ATOM   436  C CA  . ASN   A 1 140 ? 137.158 127.433 189.541 1.00 95.41  ? 129 ASN   A CA  1 
ATOM   437  C C   . ASN   A 1 140 ? 135.647 127.443 189.345 1.00 100.32 ? 129 ASN   A C   1 
ATOM   438  O O   . ASN   A 1 140 ? 134.898 127.396 190.327 1.00 104.39 ? 129 ASN   A O   1 
ATOM   439  C CB  . ASN   A 1 140 ? 137.643 128.820 189.965 1.00 95.51  ? 129 ASN   A CB  1 
ATOM   440  C CG  . ASN   A 1 140 ? 137.193 129.194 191.362 1.00 101.31 ? 129 ASN   A CG  1 
ATOM   441  O OD1 . ASN   A 1 140 ? 136.963 128.327 192.203 1.00 100.96 ? 129 ASN   A OD1 1 
ATOM   442  N ND2 . ASN   A 1 140 ? 137.062 130.491 191.614 1.00 99.84  ? 129 ASN   A ND2 1 
ATOM   443  N N   . TYR   A 1 141 ? 135.178 127.503 188.096 1.00 99.70  ? 130 TYR   A N   1 
ATOM   444  C CA  . TYR   A 1 141 ? 133.740 127.528 187.849 1.00 101.81 ? 130 TYR   A CA  1 
ATOM   445  C C   . TYR   A 1 141 ? 133.074 126.209 188.219 1.00 104.26 ? 130 TYR   A C   1 
ATOM   446  O O   . TYR   A 1 141 ? 131.847 126.154 188.364 1.00 106.75 ? 130 TYR   A O   1 
ATOM   447  C CB  . TYR   A 1 141 ? 133.465 127.861 186.382 1.00 101.09 ? 130 TYR   A CB  1 
ATOM   448  C CG  . TYR   A 1 141 ? 133.532 129.336 186.060 1.00 96.82  ? 130 TYR   A CG  1 
ATOM   449  C CD1 . TYR   A 1 141 ? 132.652 130.234 186.650 1.00 94.39  ? 130 TYR   A CD1 1 
ATOM   450  C CD2 . TYR   A 1 141 ? 134.469 129.830 185.163 1.00 97.16  ? 130 TYR   A CD2 1 
ATOM   451  C CE1 . TYR   A 1 141 ? 132.707 131.583 186.357 1.00 97.81  ? 130 TYR   A CE1 1 
ATOM   452  C CE2 . TYR   A 1 141 ? 134.532 131.177 184.864 1.00 98.42  ? 130 TYR   A CE2 1 
ATOM   453  C CZ  . TYR   A 1 141 ? 133.648 132.049 185.464 1.00 101.43 ? 130 TYR   A CZ  1 
ATOM   454  O OH  . TYR   A 1 141 ? 133.705 133.392 185.170 1.00 105.76 ? 130 TYR   A OH  1 
ATOM   455  N N   . LEU   A 1 142 ? 133.853 125.141 188.376 1.00 102.62 ? 131 LEU   A N   1 
ATOM   456  C CA  . LEU   A 1 142 ? 133.306 123.812 188.609 1.00 106.00 ? 131 LEU   A CA  1 
ATOM   457  C C   . LEU   A 1 142 ? 133.105 123.486 190.084 1.00 111.40 ? 131 LEU   A C   1 
ATOM   458  O O   . LEU   A 1 142 ? 132.224 122.683 190.408 1.00 117.65 ? 131 LEU   A O   1 
ATOM   459  C CB  . LEU   A 1 142 ? 134.212 122.753 187.973 1.00 108.56 ? 131 LEU   A CB  1 
ATOM   460  N N   . MET   A 1 143 ? 133.889 124.078 190.985 1.00 109.06 ? 132 MET   A N   1 
ATOM   461  C CA  . MET   A 1 143 ? 133.764 123.755 192.401 1.00 108.13 ? 132 MET   A CA  1 
ATOM   462  C C   . MET   A 1 143 ? 133.717 125.009 193.265 1.00 107.10 ? 132 MET   A C   1 
ATOM   463  O O   . MET   A 1 143 ? 133.315 124.948 194.431 1.00 109.40 ? 132 MET   A O   1 
ATOM   464  C CB  . MET   A 1 143 ? 134.916 122.853 192.853 1.00 107.82 ? 132 MET   A CB  1 
ATOM   465  C CG  . MET   A 1 143 ? 136.295 123.477 192.712 1.00 106.17 ? 132 MET   A CG  1 
ATOM   466  S SD  . MET   A 1 143 ? 136.869 123.532 191.007 1.00 104.31 ? 132 MET   A SD  1 
ATOM   467  C CE  . MET   A 1 143 ? 137.509 121.872 190.809 1.00 99.62  ? 132 MET   A CE  1 
ATOM   468  N N   . GLY   A 1 144 ? 134.122 126.145 192.708 1.00 106.75 ? 133 GLY   A N   1 
ATOM   469  C CA  . GLY   A 1 144 ? 134.205 127.365 193.492 1.00 108.73 ? 133 GLY   A CA  1 
ATOM   470  C C   . GLY   A 1 144 ? 135.275 127.325 194.562 1.00 110.54 ? 133 GLY   A C   1 
ATOM   471  O O   . GLY   A 1 144 ? 135.068 127.851 195.663 1.00 110.68 ? 133 GLY   A O   1 
ATOM   472  N N   . THR   A 1 145 ? 136.419 126.712 194.264 1.00 109.34 ? 134 THR   A N   1 
ATOM   473  C CA  . THR   A 1 145 ? 137.508 126.585 195.221 1.00 108.00 ? 134 THR   A CA  1 
ATOM   474  C C   . THR   A 1 145 ? 138.822 126.799 194.481 1.00 102.78 ? 134 THR   A C   1 
ATOM   475  O O   . THR   A 1 145 ? 138.909 126.606 193.266 1.00 104.09 ? 134 THR   A O   1 
ATOM   476  C CB  . THR   A 1 145 ? 137.486 125.215 195.915 1.00 106.43 ? 134 THR   A CB  1 
ATOM   477  O OG1 . THR   A 1 145 ? 136.143 124.897 196.301 1.00 103.89 ? 134 THR   A OG1 1 
ATOM   478  C CG2 . THR   A 1 145 ? 138.360 125.222 197.163 1.00 108.96 ? 134 THR   A CG2 1 
ATOM   479  N N   . TRP   A 1 146 ? 139.850 127.199 195.229 1.00 97.29  ? 135 TRP   A N   1 
ATOM   480  C CA  . TRP   A 1 146 ? 141.172 127.480 194.671 1.00 94.38  ? 135 TRP   A CA  1 
ATOM   481  C C   . TRP   A 1 146 ? 142.183 126.529 195.295 1.00 94.40  ? 135 TRP   A C   1 
ATOM   482  O O   . TRP   A 1 146 ? 142.826 126.857 196.301 1.00 93.52  ? 135 TRP   A O   1 
ATOM   483  C CB  . TRP   A 1 146 ? 141.573 128.934 194.907 1.00 95.13  ? 135 TRP   A CB  1 
ATOM   484  C CG  . TRP   A 1 146 ? 142.870 129.308 194.261 1.00 89.76  ? 135 TRP   A CG  1 
ATOM   485  C CD1 . TRP   A 1 146 ? 144.097 129.350 194.854 1.00 91.74  ? 135 TRP   A CD1 1 
ATOM   486  C CD2 . TRP   A 1 146 ? 143.069 129.697 192.898 1.00 87.38  ? 135 TRP   A CD2 1 
ATOM   487  N NE1 . TRP   A 1 146 ? 145.050 129.739 193.944 1.00 88.46  ? 135 TRP   A NE1 1 
ATOM   488  C CE2 . TRP   A 1 146 ? 144.443 129.958 192.735 1.00 87.69  ? 135 TRP   A CE2 1 
ATOM   489  C CE3 . TRP   A 1 146 ? 142.219 129.849 191.799 1.00 88.57  ? 135 TRP   A CE3 1 
ATOM   490  C CZ2 . TRP   A 1 146 ? 144.987 130.362 191.519 1.00 85.24  ? 135 TRP   A CZ2 1 
ATOM   491  C CZ3 . TRP   A 1 146 ? 142.760 130.250 190.593 1.00 87.42  ? 135 TRP   A CZ3 1 
ATOM   492  C CH2 . TRP   A 1 146 ? 144.130 130.503 190.462 1.00 84.51  ? 135 TRP   A CH2 1 
ATOM   493  N N   . PRO   A 1 147 ? 142.352 125.334 194.721 1.00 98.52  ? 136 PRO   A N   1 
ATOM   494  C CA  . PRO   A 1 147 ? 143.332 124.385 195.262 1.00 100.68 ? 136 PRO   A CA  1 
ATOM   495  C C   . PRO   A 1 147 ? 144.737 124.564 194.714 1.00 97.53  ? 136 PRO   A C   1 
ATOM   496  O O   . PRO   A 1 147 ? 145.662 123.911 195.215 1.00 98.06  ? 136 PRO   A O   1 
ATOM   497  C CB  . PRO   A 1 147 ? 142.755 123.030 194.843 1.00 100.94 ? 136 PRO   A CB  1 
ATOM   498  C CG  . PRO   A 1 147 ? 142.094 123.326 193.533 1.00 100.05 ? 136 PRO   A CG  1 
ATOM   499  C CD  . PRO   A 1 147 ? 141.559 124.741 193.629 1.00 100.09 ? 136 PRO   A CD  1 
ATOM   500  N N   . PHE   A 1 148 ? 144.925 125.417 193.704 1.00 92.02  ? 137 PHE   A N   1 
ATOM   501  C CA  . PHE   A 1 148 ? 146.236 125.553 193.078 1.00 92.21  ? 137 PHE   A CA  1 
ATOM   502  C C   . PHE   A 1 148 ? 147.277 126.111 194.041 1.00 93.35  ? 137 PHE   A C   1 
ATOM   503  O O   . PHE   A 1 148 ? 148.424 125.652 194.041 1.00 94.07  ? 137 PHE   A O   1 
ATOM   504  C CB  . PHE   A 1 148 ? 146.131 126.436 191.836 1.00 96.25  ? 137 PHE   A CB  1 
ATOM   505  C CG  . PHE   A 1 148 ? 145.230 125.881 190.769 1.00 94.33  ? 137 PHE   A CG  1 
ATOM   506  C CD1 . PHE   A 1 148 ? 145.649 124.834 189.966 1.00 89.57  ? 137 PHE   A CD1 1 
ATOM   507  C CD2 . PHE   A 1 148 ? 143.965 126.407 190.569 1.00 90.93  ? 137 PHE   A CD2 1 
ATOM   508  C CE1 . PHE   A 1 148 ? 144.823 124.322 188.983 1.00 81.88  ? 137 PHE   A CE1 1 
ATOM   509  C CE2 . PHE   A 1 148 ? 143.134 125.899 189.587 1.00 85.53  ? 137 PHE   A CE2 1 
ATOM   510  C CZ  . PHE   A 1 148 ? 143.564 124.855 188.794 1.00 80.28  ? 137 PHE   A CZ  1 
ATOM   511  N N   . GLY   A 1 149 ? 146.906 127.090 194.862 1.00 93.04  ? 138 GLY   A N   1 
ATOM   512  C CA  . GLY   A 1 149 ? 147.846 127.674 195.798 1.00 92.23  ? 138 GLY   A CA  1 
ATOM   513  C C   . GLY   A 1 149 ? 147.817 129.188 195.821 1.00 90.89  ? 138 GLY   A C   1 
ATOM   514  O O   . GLY   A 1 149 ? 147.394 129.822 194.850 1.00 88.55  ? 138 GLY   A O   1 
ATOM   515  N N   . THR   A 1 150 ? 148.265 129.780 196.932 1.00 91.99  ? 139 THR   A N   1 
ATOM   516  C CA  . THR   A 1 150 ? 148.232 131.233 197.057 1.00 92.38  ? 139 THR   A CA  1 
ATOM   517  C C   . THR   A 1 150 ? 149.265 131.907 196.162 1.00 91.90  ? 139 THR   A C   1 
ATOM   518  O O   . THR   A 1 150 ? 149.038 133.030 195.699 1.00 93.58  ? 139 THR   A O   1 
ATOM   519  C CB  . THR   A 1 150 ? 148.435 131.644 198.518 1.00 93.12  ? 139 THR   A CB  1 
ATOM   520  O OG1 . THR   A 1 150 ? 148.346 133.070 198.634 1.00 93.31  ? 139 THR   A OG1 1 
ATOM   521  C CG2 . THR   A 1 150 ? 149.788 131.174 199.036 1.00 92.91  ? 139 THR   A CG2 1 
ATOM   522  N N   . ILE   A 1 151 ? 150.399 131.250 195.907 1.00 93.84  ? 140 ILE   A N   1 
ATOM   523  C CA  . ILE   A 1 151 ? 151.406 131.823 195.016 1.00 89.74  ? 140 ILE   A CA  1 
ATOM   524  C C   . ILE   A 1 151 ? 150.863 131.917 193.594 1.00 83.53  ? 140 ILE   A C   1 
ATOM   525  O O   . ILE   A 1 151 ? 151.063 132.919 192.895 1.00 80.62  ? 140 ILE   A O   1 
ATOM   526  C CB  . ILE   A 1 151 ? 152.710 131.006 195.077 1.00 93.88  ? 140 ILE   A CB  1 
ATOM   527  C CG1 . ILE   A 1 151 ? 152.456 129.606 195.647 1.00 96.90  ? 140 ILE   A CG1 1 
ATOM   528  C CG2 . ILE   A 1 151 ? 153.759 131.738 195.901 1.00 88.39  ? 140 ILE   A CG2 1 
ATOM   529  C CD1 . ILE   A 1 151 ? 151.927 128.605 194.640 1.00 89.05  ? 140 ILE   A CD1 1 
ATOM   530  N N   . LEU   A 1 152 ? 150.170 130.869 193.144 1.00 84.97  ? 141 LEU   A N   1 
ATOM   531  C CA  . LEU   A 1 152 ? 149.563 130.903 191.819 1.00 88.92  ? 141 LEU   A CA  1 
ATOM   532  C C   . LEU   A 1 152 ? 148.466 131.956 191.747 1.00 84.09  ? 141 LEU   A C   1 
ATOM   533  O O   . LEU   A 1 152 ? 148.301 132.617 190.717 1.00 77.80  ? 141 LEU   A O   1 
ATOM   534  C CB  . LEU   A 1 152 ? 149.021 129.522 191.451 1.00 94.41  ? 141 LEU   A CB  1 
ATOM   535  C CG  . LEU   A 1 152 ? 150.105 128.477 191.171 1.00 96.43  ? 141 LEU   A CG  1 
ATOM   536  C CD1 . LEU   A 1 152 ? 149.496 127.145 190.760 1.00 94.71  ? 141 LEU   A CD1 1 
ATOM   537  C CD2 . LEU   A 1 152 ? 151.070 128.982 190.108 1.00 88.48  ? 141 LEU   A CD2 1 
ATOM   538  N N   . CYS   A 1 153 ? 147.707 132.130 192.832 1.00 85.88  ? 142 CYS   A N   1 
ATOM   539  C CA  . CYS   A 1 153 ? 146.723 133.208 192.880 1.00 84.85  ? 142 CYS   A CA  1 
ATOM   540  C C   . CYS   A 1 153 ? 147.398 134.567 192.740 1.00 74.39  ? 142 CYS   A C   1 
ATOM   541  O O   . CYS   A 1 153 ? 146.921 135.439 192.001 1.00 72.27  ? 142 CYS   A O   1 
ATOM   542  C CB  . CYS   A 1 153 ? 145.928 133.133 194.185 1.00 89.27  ? 142 CYS   A CB  1 
ATOM   543  S SG  . CYS   A 1 153 ? 145.279 134.721 194.759 1.00 82.45  ? 142 CYS   A SG  1 
ATOM   544  N N   . LYS   A 1 154 ? 148.519 134.758 193.439 1.00 74.94  ? 143 LYS   A N   1 
ATOM   545  C CA  . LYS   A 1 154 ? 149.274 136.001 193.328 1.00 76.68  ? 143 LYS   A CA  1 
ATOM   546  C C   . LYS   A 1 154 ? 149.712 136.246 191.892 1.00 77.59  ? 143 LYS   A C   1 
ATOM   547  O O   . LYS   A 1 154 ? 149.532 137.343 191.351 1.00 76.83  ? 143 LYS   A O   1 
ATOM   548  C CB  . LYS   A 1 154 ? 150.494 135.955 194.250 1.00 82.57  ? 143 LYS   A CB  1 
ATOM   549  C CG  . LYS   A 1 154 ? 150.355 136.734 195.544 1.00 88.02  ? 143 LYS   A CG  1 
ATOM   550  C CD  . LYS   A 1 154 ? 151.638 136.651 196.359 1.00 88.15  ? 143 LYS   A CD  1 
ATOM   551  C CE  . LYS   A 1 154 ? 151.647 137.654 197.502 1.00 88.05  ? 143 LYS   A CE  1 
ATOM   552  N NZ  . LYS   A 1 154 ? 150.478 137.479 198.406 1.00 92.30  ? 143 LYS   A NZ  1 
ATOM   553  N N   . ILE   A 1 155 ? 150.287 135.223 191.256 1.00 80.82  ? 144 ILE   A N   1 
ATOM   554  C CA  . ILE   A 1 155 ? 150.804 135.385 189.898 1.00 79.05  ? 144 ILE   A CA  1 
ATOM   555  C C   . ILE   A 1 155 ? 149.670 135.668 188.920 1.00 68.81  ? 144 ILE   A C   1 
ATOM   556  O O   . ILE   A 1 155 ? 149.790 136.530 188.041 1.00 65.05  ? 144 ILE   A O   1 
ATOM   557  C CB  . ILE   A 1 155 ? 151.618 134.146 189.481 1.00 82.47  ? 144 ILE   A CB  1 
ATOM   558  C CG1 . ILE   A 1 155 ? 152.835 133.976 190.393 1.00 82.08  ? 144 ILE   A CG1 1 
ATOM   559  C CG2 . ILE   A 1 155 ? 152.058 134.259 188.029 1.00 80.50  ? 144 ILE   A CG2 1 
ATOM   560  C CD1 . ILE   A 1 155 ? 153.268 132.535 190.575 1.00 80.97  ? 144 ILE   A CD1 1 
ATOM   561  N N   . VAL   A 1 156 ? 148.551 134.954 189.060 1.00 63.34  ? 145 VAL   A N   1 
ATOM   562  C CA  . VAL   A 1 156 ? 147.419 135.149 188.161 1.00 58.51  ? 145 VAL   A CA  1 
ATOM   563  C C   . VAL   A 1 156 ? 146.861 136.560 188.301 1.00 62.14  ? 145 VAL   A C   1 
ATOM   564  O O   . VAL   A 1 156 ? 146.631 137.257 187.303 1.00 66.54  ? 145 VAL   A O   1 
ATOM   565  C CB  . VAL   A 1 156 ? 146.339 134.086 188.430 1.00 58.72  ? 145 VAL   A CB  1 
ATOM   566  C CG1 . VAL   A 1 156 ? 145.026 134.483 187.780 1.00 56.68  ? 145 VAL   A CG1 1 
ATOM   567  C CG2 . VAL   A 1 156 ? 146.797 132.728 187.927 1.00 70.83  ? 145 VAL   A CG2 1 
ATOM   568  N N   . ILE   A 1 157 ? 146.644 137.008 189.540 1.00 61.44  ? 146 ILE   A N   1 
ATOM   569  C CA  . ILE   A 1 157 ? 146.077 138.335 189.752 1.00 55.25  ? 146 ILE   A CA  1 
ATOM   570  C C   . ILE   A 1 157 ? 147.042 139.413 189.270 1.00 51.51  ? 146 ILE   A C   1 
ATOM   571  O O   . ILE   A 1 157 ? 146.625 140.419 188.685 1.00 47.89  ? 146 ILE   A O   1 
ATOM   572  C CB  . ILE   A 1 157 ? 145.695 138.515 191.232 1.00 57.45  ? 146 ILE   A CB  1 
ATOM   573  C CG1 . ILE   A 1 157 ? 144.329 137.881 191.504 1.00 54.17  ? 146 ILE   A CG1 1 
ATOM   574  C CG2 . ILE   A 1 157 ? 145.676 139.981 191.614 1.00 64.32  ? 146 ILE   A CG2 1 
ATOM   575  C CD1 . ILE   A 1 157 ? 143.176 138.608 190.847 1.00 49.65  ? 146 ILE   A CD1 1 
ATOM   576  N N   . SER   A 1 158 ? 148.345 139.215 189.489 1.00 52.63  ? 147 SER   A N   1 
ATOM   577  C CA  . SER   A 1 158 ? 149.330 140.179 189.013 1.00 56.61  ? 147 SER   A CA  1 
ATOM   578  C C   . SER   A 1 158 ? 149.363 140.257 187.493 1.00 58.63  ? 147 SER   A C   1 
ATOM   579  O O   . SER   A 1 158 ? 149.457 141.355 186.934 1.00 59.97  ? 147 SER   A O   1 
ATOM   580  C CB  . SER   A 1 158 ? 150.715 139.825 189.552 1.00 63.70  ? 147 SER   A CB  1 
ATOM   581  O OG  . SER   A 1 158 ? 151.698 140.717 189.057 1.00 64.41  ? 147 SER   A OG  1 
ATOM   582  N N   . ILE   A 1 159 ? 149.291 139.114 186.805 1.00 60.02  ? 148 ILE   A N   1 
ATOM   583  C CA  . ILE   A 1 159 ? 149.331 139.138 185.345 1.00 53.53  ? 148 ILE   A CA  1 
ATOM   584  C C   . ILE   A 1 159 ? 148.046 139.739 184.788 1.00 52.25  ? 148 ILE   A C   1 
ATOM   585  O O   . ILE   A 1 159 ? 148.055 140.388 183.733 1.00 56.47  ? 148 ILE   A O   1 
ATOM   586  C CB  . ILE   A 1 159 ? 149.604 137.727 184.787 1.00 55.08  ? 148 ILE   A CB  1 
ATOM   587  C CG1 . ILE   A 1 159 ? 150.342 137.823 183.452 1.00 53.21  ? 148 ILE   A CG1 1 
ATOM   588  C CG2 . ILE   A 1 159 ? 148.321 136.933 184.620 1.00 54.30  ? 148 ILE   A CG2 1 
ATOM   589  C CD1 . ILE   A 1 159 ? 151.717 138.432 183.567 1.00 51.12  ? 148 ILE   A CD1 1 
ATOM   590  N N   . ASP   A 1 160 ? 146.928 139.561 185.502 1.00 49.23  ? 149 ASP   A N   1 
ATOM   591  C CA  . ASP   A 1 160 ? 145.669 140.152 185.059 1.00 50.62  ? 149 ASP   A CA  1 
ATOM   592  C C   . ASP   A 1 160 ? 145.750 141.671 184.996 1.00 52.99  ? 149 ASP   A C   1 
ATOM   593  O O   . ASP   A 1 160 ? 145.067 142.294 184.176 1.00 47.48  ? 149 ASP   A O   1 
ATOM   594  C CB  . ASP   A 1 160 ? 144.532 139.721 185.984 1.00 50.09  ? 149 ASP   A CB  1 
ATOM   595  C CG  . ASP   A 1 160 ? 143.874 138.436 185.535 1.00 51.21  ? 149 ASP   A CG  1 
ATOM   596  O OD1 . ASP   A 1 160 ? 144.436 137.761 184.648 1.00 53.09  ? 149 ASP   A OD1 1 
ATOM   597  O OD2 . ASP   A 1 160 ? 142.794 138.102 186.066 1.00 50.78  ? 149 ASP   A OD2 1 
ATOM   598  N N   . TYR   A 1 161 ? 146.572 142.285 185.847 1.00 52.53  ? 150 TYR   A N   1 
ATOM   599  C CA  . TYR   A 1 161 ? 146.756 143.730 185.821 1.00 46.18  ? 150 TYR   A CA  1 
ATOM   600  C C   . TYR   A 1 161 ? 147.952 144.140 184.971 1.00 42.58  ? 150 TYR   A C   1 
ATOM   601  O O   . TYR   A 1 161 ? 148.001 145.269 184.473 1.00 48.86  ? 150 TYR   A O   1 
ATOM   602  C CB  . TYR   A 1 161 ? 146.916 144.270 187.244 1.00 52.05  ? 150 TYR   A CB  1 
ATOM   603  C CG  . TYR   A 1 161 ? 145.608 144.417 187.984 1.00 53.77  ? 150 TYR   A CG  1 
ATOM   604  C CD1 . TYR   A 1 161 ? 145.037 143.336 188.642 1.00 54.34  ? 150 TYR   A CD1 1 
ATOM   605  C CD2 . TYR   A 1 161 ? 144.939 145.631 188.017 1.00 52.77  ? 150 TYR   A CD2 1 
ATOM   606  C CE1 . TYR   A 1 161 ? 143.841 143.463 189.320 1.00 52.81  ? 150 TYR   A CE1 1 
ATOM   607  C CE2 . TYR   A 1 161 ? 143.741 145.767 188.689 1.00 56.13  ? 150 TYR   A CE2 1 
ATOM   608  C CZ  . TYR   A 1 161 ? 143.197 144.680 189.338 1.00 54.73  ? 150 TYR   A CZ  1 
ATOM   609  O OH  . TYR   A 1 161 ? 142.003 144.810 190.010 1.00 58.20  ? 150 TYR   A OH  1 
ATOM   610  N N   . TYR   A 1 162 ? 148.923 143.243 184.805 1.00 39.22  ? 151 TYR   A N   1 
ATOM   611  C CA  . TYR   A 1 162 ? 150.063 143.536 183.944 1.00 46.14  ? 151 TYR   A CA  1 
ATOM   612  C C   . TYR   A 1 162 ? 149.655 143.579 182.478 1.00 45.36  ? 151 TYR   A C   1 
ATOM   613  O O   . TYR   A 1 162 ? 150.229 144.348 181.693 1.00 44.36  ? 151 TYR   A O   1 
ATOM   614  C CB  . TYR   A 1 162 ? 151.148 142.482 184.150 1.00 53.20  ? 151 TYR   A CB  1 
ATOM   615  C CG  . TYR   A 1 162 ? 152.369 142.966 184.896 1.00 64.52  ? 151 TYR   A CG  1 
ATOM   616  C CD1 . TYR   A 1 162 ? 153.224 143.909 184.343 1.00 64.65  ? 151 TYR   A CD1 1 
ATOM   617  C CD2 . TYR   A 1 162 ? 152.671 142.465 186.155 1.00 66.25  ? 151 TYR   A CD2 1 
ATOM   618  C CE1 . TYR   A 1 162 ? 154.343 144.344 185.030 1.00 67.12  ? 151 TYR   A CE1 1 
ATOM   619  C CE2 . TYR   A 1 162 ? 153.783 142.893 186.846 1.00 70.28  ? 151 TYR   A CE2 1 
ATOM   620  C CZ  . TYR   A 1 162 ? 154.615 143.831 186.281 1.00 71.57  ? 151 TYR   A CZ  1 
ATOM   621  O OH  . TYR   A 1 162 ? 155.723 144.248 186.978 1.00 73.45  ? 151 TYR   A OH  1 
ATOM   622  N N   . ASN   A 1 163 ? 148.681 142.749 182.094 1.00 43.64  ? 152 ASN   A N   1 
ATOM   623  C CA  . ASN   A 1 163 ? 148.330 142.595 180.685 1.00 38.93  ? 152 ASN   A CA  1 
ATOM   624  C C   . ASN   A 1 163 ? 147.828 143.903 180.084 1.00 38.35  ? 152 ASN   A C   1 
ATOM   625  O O   . ASN   A 1 163 ? 148.281 144.317 179.008 1.00 43.90  ? 152 ASN   A O   1 
ATOM   626  C CB  . ASN   A 1 163 ? 147.281 141.494 180.532 1.00 35.55  ? 152 ASN   A CB  1 
ATOM   627  C CG  . ASN   A 1 163 ? 146.860 141.286 179.096 1.00 41.75  ? 152 ASN   A CG  1 
ATOM   628  O OD1 . ASN   A 1 163 ? 147.685 141.314 178.184 1.00 44.72  ? 152 ASN   A OD1 1 
ATOM   629  N ND2 . ASN   A 1 163 ? 145.569 141.061 178.885 1.00 49.92  ? 152 ASN   A ND2 1 
ATOM   630  N N   . MET   A 1 164 ? 146.883 144.563 180.762 1.00 35.54  ? 153 MET   A N   1 
ATOM   631  C CA  . MET   A 1 164 ? 146.314 145.797 180.228 1.00 32.82  ? 153 MET   A CA  1 
ATOM   632  C C   . MET   A 1 164 ? 147.395 146.834 179.981 1.00 32.33  ? 153 MET   A C   1 
ATOM   633  O O   . MET   A 1 164 ? 147.490 147.405 178.888 1.00 33.18  ? 153 MET   A O   1 
ATOM   634  C CB  . MET   A 1 164 ? 145.276 146.370 181.189 1.00 30.81  ? 153 MET   A CB  1 
ATOM   635  C CG  . MET   A 1 164 ? 143.904 145.788 181.056 1.00 28.84  ? 153 MET   A CG  1 
ATOM   636  S SD  . MET   A 1 164 ? 143.042 145.825 182.631 1.00 44.17  ? 153 MET   A SD  1 
ATOM   637  C CE  . MET   A 1 164 ? 144.376 145.401 183.738 1.00 42.43  ? 153 MET   A CE  1 
ATOM   638  N N   . PHE   A 1 165 ? 148.216 147.093 180.998 1.00 30.83  ? 154 PHE   A N   1 
ATOM   639  C CA  . PHE   A 1 165 ? 149.230 148.132 180.891 1.00 36.08  ? 154 PHE   A CA  1 
ATOM   640  C C   . PHE   A 1 165 ? 150.237 147.800 179.801 1.00 36.25  ? 154 PHE   A C   1 
ATOM   641  O O   . PHE   A 1 165 ? 150.542 148.645 178.948 1.00 38.72  ? 154 PHE   A O   1 
ATOM   642  C CB  . PHE   A 1 165 ? 149.926 148.318 182.238 1.00 38.93  ? 154 PHE   A CB  1 
ATOM   643  C CG  . PHE   A 1 165 ? 149.158 149.170 183.200 1.00 32.83  ? 154 PHE   A CG  1 
ATOM   644  C CD1 . PHE   A 1 165 ? 147.870 148.828 183.570 1.00 27.04  ? 154 PHE   A CD1 1 
ATOM   645  C CD2 . PHE   A 1 165 ? 149.720 150.314 183.732 1.00 39.09  ? 154 PHE   A CD2 1 
ATOM   646  C CE1 . PHE   A 1 165 ? 147.159 149.608 184.450 1.00 26.22  ? 154 PHE   A CE1 1 
ATOM   647  C CE2 . PHE   A 1 165 ? 149.011 151.101 184.614 1.00 38.29  ? 154 PHE   A CE2 1 
ATOM   648  C CZ  . PHE   A 1 165 ? 147.728 150.746 184.975 1.00 31.11  ? 154 PHE   A CZ  1 
ATOM   649  N N   . THR   A 1 166 ? 150.744 146.563 179.793 1.00 33.71  ? 155 THR   A N   1 
ATOM   650  C CA  . THR   A 1 166 ? 151.721 146.181 178.781 1.00 38.84  ? 155 THR   A CA  1 
ATOM   651  C C   . THR   A 1 166 ? 151.159 146.379 177.381 1.00 39.01  ? 155 THR   A C   1 
ATOM   652  O O   . THR   A 1 166 ? 151.772 147.053 176.543 1.00 40.13  ? 155 THR   A O   1 
ATOM   653  C CB  . THR   A 1 166 ? 152.153 144.728 178.984 1.00 41.58  ? 155 THR   A CB  1 
ATOM   654  O OG1 . THR   A 1 166 ? 150.997 143.913 179.215 1.00 39.44  ? 155 THR   A OG1 1 
ATOM   655  C CG2 . THR   A 1 166 ? 153.097 144.610 180.169 1.00 49.59  ? 155 THR   A CG2 1 
ATOM   656  N N   . SER   A 1 167 ? 149.970 145.833 177.121 1.00 33.03  ? 156 SER   A N   1 
ATOM   657  C CA  . SER   A 1 167 ? 149.419 145.875 175.773 1.00 26.72  ? 156 SER   A CA  1 
ATOM   658  C C   . SER   A 1 167 ? 149.102 147.302 175.338 1.00 29.13  ? 156 SER   A C   1 
ATOM   659  O O   . SER   A 1 167 ? 149.421 147.700 174.211 1.00 33.08  ? 156 SER   A O   1 
ATOM   660  C CB  . SER   A 1 167 ? 148.176 144.995 175.699 1.00 25.52  ? 156 SER   A CB  1 
ATOM   661  O OG  . SER   A 1 167 ? 148.498 143.645 175.983 1.00 32.24  ? 156 SER   A OG  1 
ATOM   662  N N   . ILE   A 1 168 ? 148.481 148.095 176.216 1.00 30.85  ? 157 ILE   A N   1 
ATOM   663  C CA  . ILE   A 1 168 ? 148.054 149.428 175.803 1.00 27.28  ? 157 ILE   A CA  1 
ATOM   664  C C   . ILE   A 1 168 ? 149.254 150.348 175.610 1.00 23.25  ? 157 ILE   A C   1 
ATOM   665  O O   . ILE   A 1 168 ? 149.285 151.153 174.670 1.00 25.77  ? 157 ILE   A O   1 
ATOM   666  C CB  . ILE   A 1 168 ? 147.037 150.010 176.799 1.00 25.17  ? 157 ILE   A CB  1 
ATOM   667  C CG1 . ILE   A 1 168 ? 146.318 151.202 176.170 1.00 16.74  ? 157 ILE   A CG1 1 
ATOM   668  C CG2 . ILE   A 1 168 ? 147.709 150.411 178.100 1.00 30.02  ? 157 ILE   A CG2 1 
ATOM   669  C CD1 . ILE   A 1 168 ? 145.393 150.835 175.039 1.00 11.02  ? 157 ILE   A CD1 1 
ATOM   670  N N   . PHE   A 1 169 ? 150.264 150.250 176.479 1.00 25.84  ? 158 PHE   A N   1 
ATOM   671  C CA  . PHE   A 1 169 ? 151.450 151.072 176.283 1.00 31.65  ? 158 PHE   A CA  1 
ATOM   672  C C   . PHE   A 1 169 ? 152.207 150.634 175.039 1.00 32.48  ? 158 PHE   A C   1 
ATOM   673  O O   . PHE   A 1 169 ? 152.783 151.469 174.332 1.00 29.68  ? 158 PHE   A O   1 
ATOM   674  C CB  . PHE   A 1 169 ? 152.347 151.008 177.515 1.00 39.60  ? 158 PHE   A CB  1 
ATOM   675  C CG  . PHE   A 1 169 ? 151.713 151.556 178.757 1.00 36.96  ? 158 PHE   A CG  1 
ATOM   676  C CD1 . PHE   A 1 169 ? 150.674 152.465 178.678 1.00 33.25  ? 158 PHE   A CD1 1 
ATOM   677  C CD2 . PHE   A 1 169 ? 152.155 151.158 180.006 1.00 45.62  ? 158 PHE   A CD2 1 
ATOM   678  C CE1 . PHE   A 1 169 ? 150.090 152.966 179.819 1.00 31.27  ? 158 PHE   A CE1 1 
ATOM   679  C CE2 . PHE   A 1 169 ? 151.573 151.657 181.150 1.00 49.60  ? 158 PHE   A CE2 1 
ATOM   680  C CZ  . PHE   A 1 169 ? 150.540 152.563 181.057 1.00 39.02  ? 158 PHE   A CZ  1 
ATOM   681  N N   . THR   A 1 170 ? 152.205 149.331 174.746 1.00 32.20  ? 159 THR   A N   1 
ATOM   682  C CA  . THR   A 1 170 ? 152.813 148.853 173.511 1.00 32.87  ? 159 THR   A CA  1 
ATOM   683  C C   . THR   A 1 170 ? 152.119 149.446 172.293 1.00 32.39  ? 159 THR   A C   1 
ATOM   684  O O   . THR   A 1 170 ? 152.779 149.884 171.344 1.00 36.89  ? 159 THR   A O   1 
ATOM   685  C CB  . THR   A 1 170 ? 152.761 147.329 173.469 1.00 38.51  ? 159 THR   A CB  1 
ATOM   686  O OG1 . THR   A 1 170 ? 153.481 146.798 174.586 1.00 40.04  ? 159 THR   A OG1 1 
ATOM   687  C CG2 . THR   A 1 170 ? 153.379 146.822 172.195 1.00 45.94  ? 159 THR   A CG2 1 
ATOM   688  N N   . LEU   A 1 171 ? 150.785 149.472 172.303 1.00 25.79  ? 160 LEU   A N   1 
ATOM   689  C CA  . LEU   A 1 171 ? 150.055 150.053 171.181 1.00 21.21  ? 160 LEU   A CA  1 
ATOM   690  C C   . LEU   A 1 171 ? 150.325 151.547 171.052 1.00 25.22  ? 160 LEU   A C   1 
ATOM   691  O O   . LEU   A 1 171 ? 150.479 152.062 169.939 1.00 30.90  ? 160 LEU   A O   1 
ATOM   692  C CB  . LEU   A 1 171 ? 148.561 149.798 171.334 1.00 14.65  ? 160 LEU   A CB  1 
ATOM   693  C CG  . LEU   A 1 171 ? 148.158 148.330 171.330 1.00 18.17  ? 160 LEU   A CG  1 
ATOM   694  C CD1 . LEU   A 1 171 ? 146.689 148.247 171.589 1.00 17.25  ? 160 LEU   A CD1 1 
ATOM   695  C CD2 . LEU   A 1 171 ? 148.513 147.675 170.009 1.00 26.61  ? 160 LEU   A CD2 1 
ATOM   696  N N   . CYS   A 1 172 ? 150.364 152.264 172.177 1.00 25.86  ? 161 CYS   A N   1 
ATOM   697  C CA  . CYS   A 1 172 ? 150.656 153.693 172.122 1.00 19.35  ? 161 CYS   A CA  1 
ATOM   698  C C   . CYS   A 1 172 ? 152.048 153.946 171.558 1.00 24.64  ? 161 CYS   A C   1 
ATOM   699  O O   . CYS   A 1 172 ? 152.242 154.854 170.737 1.00 29.35  ? 161 CYS   A O   1 
ATOM   700  C CB  . CYS   A 1 172 ? 150.518 154.311 173.511 1.00 20.49  ? 161 CYS   A CB  1 
ATOM   701  S SG  . CYS   A 1 172 ? 151.400 155.872 173.722 1.00 29.97  ? 161 CYS   A SG  1 
ATOM   702  N N   . THR   A 1 173 ? 153.029 153.146 171.978 1.00 27.79  ? 162 THR   A N   1 
ATOM   703  C CA  . THR   A 1 173 ? 154.380 153.295 171.451 1.00 30.85  ? 162 THR   A CA  1 
ATOM   704  C C   . THR   A 1 173 ? 154.426 152.975 169.963 1.00 34.73  ? 162 THR   A C   1 
ATOM   705  O O   . THR   A 1 173 ? 155.125 153.647 169.199 1.00 39.09  ? 162 THR   A O   1 
ATOM   706  C CB  . THR   A 1 173 ? 155.349 152.403 172.225 1.00 37.11  ? 162 THR   A CB  1 
ATOM   707  O OG1 . THR   A 1 173 ? 154.829 151.069 172.286 1.00 38.19  ? 162 THR   A OG1 1 
ATOM   708  C CG2 . THR   A 1 173 ? 155.523 152.927 173.639 1.00 43.55  ? 162 THR   A CG2 1 
ATOM   709  N N   . MET   A 1 174 ? 153.680 151.955 169.531 1.00 32.10  ? 163 MET   A N   1 
ATOM   710  C CA  . MET   A 1 174 ? 153.626 151.626 168.110 1.00 31.21  ? 163 MET   A CA  1 
ATOM   711  C C   . MET   A 1 174 ? 153.021 152.766 167.299 1.00 29.89  ? 163 MET   A C   1 
ATOM   712  O O   . MET   A 1 174 ? 153.534 153.120 166.230 1.00 36.29  ? 163 MET   A O   1 
ATOM   713  C CB  . MET   A 1 174 ? 152.833 150.334 167.907 1.00 27.88  ? 163 MET   A CB  1 
ATOM   714  C CG  . MET   A 1 174 ? 153.495 149.330 166.980 1.00 38.90  ? 163 MET   A CG  1 
ATOM   715  S SD  . MET   A 1 174 ? 152.749 147.689 167.056 1.00 41.63  ? 163 MET   A SD  1 
ATOM   716  C CE  . MET   A 1 174 ? 151.014 148.078 166.857 1.00 32.28  ? 163 MET   A CE  1 
ATOM   717  N N   . SER   A 1 175 ? 151.936 153.361 167.795 1.00 26.06  ? 164 SER   A N   1 
ATOM   718  C CA  . SER   A 1 175 ? 151.298 154.447 167.059 1.00 21.76  ? 164 SER   A CA  1 
ATOM   719  C C   . SER   A 1 175 ? 152.169 155.696 167.017 1.00 29.20  ? 164 SER   A C   1 
ATOM   720  O O   . SER   A 1 175 ? 152.173 156.407 166.007 1.00 37.47  ? 164 SER   A O   1 
ATOM   721  C CB  . SER   A 1 175 ? 149.934 154.772 167.663 1.00 18.18  ? 164 SER   A CB  1 
ATOM   722  O OG  . SER   A 1 175 ? 149.017 153.718 167.433 1.00 17.36  ? 164 SER   A OG  1 
ATOM   723  N N   . VAL   A 1 176 ? 152.899 155.994 168.094 1.00 30.34  ? 165 VAL   A N   1 
ATOM   724  C CA  . VAL   A 1 176 ? 153.818 157.128 168.044 1.00 32.41  ? 165 VAL   A CA  1 
ATOM   725  C C   . VAL   A 1 176 ? 154.999 156.821 167.125 1.00 39.29  ? 165 VAL   A C   1 
ATOM   726  O O   . VAL   A 1 176 ? 155.526 157.713 166.447 1.00 39.94  ? 165 VAL   A O   1 
ATOM   727  C CB  . VAL   A 1 176 ? 154.265 157.531 169.465 1.00 31.04  ? 165 VAL   A CB  1 
ATOM   728  C CG1 . VAL   A 1 176 ? 155.452 156.706 169.939 1.00 32.48  ? 165 VAL   A CG1 1 
ATOM   729  C CG2 . VAL   A 1 176 ? 154.597 159.013 169.511 1.00 35.08  ? 165 VAL   A CG2 1 
ATOM   730  N N   . ASP   A 1 177 ? 155.421 155.552 167.072 1.00 39.91  ? 166 ASP   A N   1 
ATOM   731  C CA  . ASP   A 1 177 ? 156.492 155.152 166.166 1.00 46.75  ? 166 ASP   A CA  1 
ATOM   732  C C   . ASP   A 1 177 ? 156.074 155.350 164.717 1.00 48.15  ? 166 ASP   A C   1 
ATOM   733  O O   . ASP   A 1 177 ? 156.874 155.793 163.883 1.00 49.96  ? 166 ASP   A O   1 
ATOM   734  C CB  . ASP   A 1 177 ? 156.869 153.692 166.440 1.00 47.63  ? 166 ASP   A CB  1 
ATOM   735  C CG  . ASP   A 1 177 ? 157.512 153.004 165.247 1.00 57.59  ? 166 ASP   A CG  1 
ATOM   736  O OD1 . ASP   A 1 177 ? 158.350 153.624 164.561 1.00 62.65  ? 166 ASP   A OD1 1 
ATOM   737  O OD2 . ASP   A 1 177 ? 157.175 151.829 164.995 1.00 59.18  ? 166 ASP   A OD2 1 
ATOM   738  N N   . ARG   A 1 178 ? 154.820 155.025 164.397 1.00 44.51  ? 167 ARG   A N   1 
ATOM   739  C CA  . ARG   A 1 178 ? 154.337 155.247 163.038 1.00 42.07  ? 167 ARG   A CA  1 
ATOM   740  C C   . ARG   A 1 178 ? 154.370 156.730 162.680 1.00 49.33  ? 167 ARG   A C   1 
ATOM   741  O O   . ARG   A 1 178 ? 154.707 157.094 161.548 1.00 56.62  ? 167 ARG   A O   1 
ATOM   742  C CB  . ARG   A 1 178 ? 152.925 154.682 162.865 1.00 33.16  ? 167 ARG   A CB  1 
ATOM   743  C CG  . ARG   A 1 178 ? 152.733 153.213 163.238 1.00 38.06  ? 167 ARG   A CG  1 
ATOM   744  C CD  . ARG   A 1 178 ? 153.945 152.344 162.934 1.00 39.14  ? 167 ARG   A CD  1 
ATOM   745  N NE  . ARG   A 1 178 ? 154.329 152.374 161.529 1.00 49.16  ? 167 ARG   A NE  1 
ATOM   746  C CZ  . ARG   A 1 178 ? 155.388 151.748 161.035 1.00 54.35  ? 167 ARG   A CZ  1 
ATOM   747  N NH1 . ARG   A 1 178 ? 156.172 151.008 161.802 1.00 55.27  ? 167 ARG   A NH1 1 
ATOM   748  N NH2 . ARG   A 1 178 ? 155.670 151.869 159.743 1.00 50.32  ? 167 ARG   A NH2 1 
ATOM   749  N N   . TYR   A 1 179 ? 154.025 157.603 163.632 1.00 49.00  ? 168 TYR   A N   1 
ATOM   750  C CA  . TYR   A 1 179 ? 154.110 159.040 163.382 1.00 45.44  ? 168 TYR   A CA  1 
ATOM   751  C C   . TYR   A 1 179 ? 155.548 159.476 163.141 1.00 49.28  ? 168 TYR   A C   1 
ATOM   752  O O   . TYR   A 1 179 ? 155.817 160.271 162.232 1.00 49.33  ? 168 TYR   A O   1 
ATOM   753  C CB  . TYR   A 1 179 ? 153.513 159.821 164.553 1.00 40.24  ? 168 TYR   A CB  1 
ATOM   754  C CG  . TYR   A 1 179 ? 153.589 161.325 164.389 1.00 43.21  ? 168 TYR   A CG  1 
ATOM   755  C CD1 . TYR   A 1 179 ? 154.697 162.040 164.829 1.00 43.75  ? 168 TYR   A CD1 1 
ATOM   756  C CD2 . TYR   A 1 179 ? 152.555 162.028 163.789 1.00 40.32  ? 168 TYR   A CD2 1 
ATOM   757  C CE1 . TYR   A 1 179 ? 154.768 163.409 164.678 1.00 43.17  ? 168 TYR   A CE1 1 
ATOM   758  C CE2 . TYR   A 1 179 ? 152.619 163.397 163.637 1.00 32.37  ? 168 TYR   A CE2 1 
ATOM   759  C CZ  . TYR   A 1 179 ? 153.725 164.082 164.081 1.00 36.30  ? 168 TYR   A CZ  1 
ATOM   760  O OH  . TYR   A 1 179 ? 153.786 165.446 163.926 1.00 39.55  ? 168 TYR   A OH  1 
ATOM   761  N N   . ILE   A 1 180 ? 156.482 158.981 163.957 1.00 53.12  ? 169 ILE   A N   1 
ATOM   762  C CA  . ILE   A 1 180 ? 157.892 159.301 163.738 1.00 60.81  ? 169 ILE   A CA  1 
ATOM   763  C C   . ILE   A 1 180 ? 158.325 158.861 162.345 1.00 64.75  ? 169 ILE   A C   1 
ATOM   764  O O   . ILE   A 1 180 ? 159.062 159.574 161.652 1.00 65.28  ? 169 ILE   A O   1 
ATOM   765  C CB  . ILE   A 1 180 ? 158.775 158.668 164.830 1.00 62.49  ? 169 ILE   A CB  1 
ATOM   766  C CG1 . ILE   A 1 180 ? 158.251 159.018 166.222 1.00 56.03  ? 169 ILE   A CG1 1 
ATOM   767  C CG2 . ILE   A 1 180 ? 160.221 159.117 164.675 1.00 71.22  ? 169 ILE   A CG2 1 
ATOM   768  C CD1 . ILE   A 1 180 ? 159.118 158.503 167.348 1.00 52.90  ? 169 ILE   A CD1 1 
ATOM   769  N N   . ALA   A 1 181 ? 157.872 157.683 161.915 1.00 60.74  ? 170 ALA   A N   1 
ATOM   770  C CA  . ALA   A 1 181 ? 158.222 157.194 160.585 1.00 62.90  ? 170 ALA   A CA  1 
ATOM   771  C C   . ALA   A 1 181 ? 157.645 158.083 159.490 1.00 64.89  ? 170 ALA   A C   1 
ATOM   772  O O   . ALA   A 1 181 ? 158.331 158.401 158.512 1.00 70.25  ? 170 ALA   A O   1 
ATOM   773  C CB  . ALA   A 1 181 ? 157.737 155.756 160.411 1.00 61.48  ? 170 ALA   A CB  1 
ATOM   774  N N   . VAL   A 1 182 ? 156.388 158.499 159.637 1.00 61.70  ? 171 VAL   A N   1 
ATOM   775  C CA  . VAL   A 1 182 ? 155.676 159.167 158.551 1.00 60.82  ? 171 VAL   A CA  1 
ATOM   776  C C   . VAL   A 1 182 ? 156.005 160.654 158.494 1.00 61.93  ? 171 VAL   A C   1 
ATOM   777  O O   . VAL   A 1 182 ? 156.568 161.136 157.505 1.00 60.51  ? 171 VAL   A O   1 
ATOM   778  C CB  . VAL   A 1 182 ? 154.157 158.955 158.681 1.00 53.05  ? 171 VAL   A CB  1 
ATOM   779  C CG1 . VAL   A 1 182 ? 153.414 159.836 157.693 1.00 51.74  ? 171 VAL   A CG1 1 
ATOM   780  C CG2 . VAL   A 1 182 ? 153.809 157.495 158.457 1.00 49.80  ? 171 VAL   A CG2 1 
ATOM   781  N N   . CYS   A 1 183 ? 155.660 161.394 159.550 1.00 65.73  ? 172 CYS   A N   1 
ATOM   782  C CA  . CYS   A 1 183 ? 155.727 162.849 159.480 1.00 63.00  ? 172 CYS   A CA  1 
ATOM   783  C C   . CYS   A 1 183 ? 157.134 163.398 159.674 1.00 65.22  ? 172 CYS   A C   1 
ATOM   784  O O   . CYS   A 1 183 ? 157.374 164.568 159.356 1.00 60.78  ? 172 CYS   A O   1 
ATOM   785  C CB  . CYS   A 1 183 ? 154.786 163.470 160.513 1.00 58.30  ? 172 CYS   A CB  1 
ATOM   786  S SG  . CYS   A 1 183 ? 153.051 163.025 160.284 1.00 52.04  ? 172 CYS   A SG  1 
ATOM   787  N N   . HIS   A 1 184 ? 158.064 162.595 160.184 1.00 71.72  ? 173 HIS   A N   1 
ATOM   788  C CA  . HIS   A 1 184 ? 159.463 163.000 160.332 1.00 77.10  ? 173 HIS   A CA  1 
ATOM   789  C C   . HIS   A 1 184 ? 160.377 161.900 159.804 1.00 84.25  ? 173 HIS   A C   1 
ATOM   790  O O   . HIS   A 1 184 ? 161.099 161.250 160.566 1.00 83.77  ? 173 HIS   A O   1 
ATOM   791  C CB  . HIS   A 1 184 ? 159.780 163.332 161.788 1.00 75.80  ? 173 HIS   A CB  1 
ATOM   792  C CG  . HIS   A 1 184 ? 158.902 164.397 162.369 1.00 66.36  ? 173 HIS   A CG  1 
ATOM   793  N ND1 . HIS   A 1 184 ? 159.163 165.742 162.216 1.00 70.34  ? 173 HIS   A ND1 1 
ATOM   794  C CD2 . HIS   A 1 184 ? 157.765 164.316 163.100 1.00 60.73  ? 173 HIS   A CD2 1 
ATOM   795  C CE1 . HIS   A 1 184 ? 158.226 166.443 162.828 1.00 67.78  ? 173 HIS   A CE1 1 
ATOM   796  N NE2 . HIS   A 1 184 ? 157.366 165.602 163.373 1.00 61.75  ? 173 HIS   A NE2 1 
ATOM   797  N N   . PRO   A 1 185 ? 160.369 161.665 158.488 1.00 86.68  ? 174 PRO   A N   1 
ATOM   798  C CA  . PRO   A 1 185 ? 161.196 160.579 157.942 1.00 90.66  ? 174 PRO   A CA  1 
ATOM   799  C C   . PRO   A 1 185 ? 162.687 160.853 158.022 1.00 97.66  ? 174 PRO   A C   1 
ATOM   800  O O   . PRO   A 1 185 ? 163.480 159.907 157.946 1.00 98.69  ? 174 PRO   A O   1 
ATOM   801  C CB  . PRO   A 1 185 ? 160.719 160.476 156.488 1.00 85.93  ? 174 PRO   A CB  1 
ATOM   802  C CG  . PRO   A 1 185 ? 160.246 161.850 156.161 1.00 81.28  ? 174 PRO   A CG  1 
ATOM   803  C CD  . PRO   A 1 185 ? 159.662 162.409 157.430 1.00 81.26  ? 174 PRO   A CD  1 
ATOM   804  N N   . VAL   A 1 186 ? 163.093 162.118 158.163 1.00 95.54  ? 175 VAL   A N   1 
ATOM   805  C CA  . VAL   A 1 186 ? 164.517 162.446 158.195 1.00 96.38  ? 175 VAL   A CA  1 
ATOM   806  C C   . VAL   A 1 186 ? 165.182 161.816 159.413 1.00 101.16 ? 175 VAL   A C   1 
ATOM   807  O O   . VAL   A 1 186 ? 166.218 161.149 159.302 1.00 104.06 ? 175 VAL   A O   1 
ATOM   808  C CB  . VAL   A 1 186 ? 164.716 163.972 158.171 1.00 92.39  ? 175 VAL   A CB  1 
ATOM   809  N N   . LYS   A 1 187 ? 164.596 162.014 160.589 1.00 99.20  ? 176 LYS   A N   1 
ATOM   810  C CA  . LYS   A 1 187 ? 165.114 161.438 161.822 1.00 100.74 ? 176 LYS   A CA  1 
ATOM   811  C C   . LYS   A 1 187 ? 164.460 160.109 162.174 1.00 102.91 ? 176 LYS   A C   1 
ATOM   812  O O   . LYS   A 1 187 ? 164.775 159.540 163.226 1.00 104.39 ? 176 LYS   A O   1 
ATOM   813  C CB  . LYS   A 1 187 ? 164.933 162.425 162.981 1.00 97.21  ? 176 LYS   A CB  1 
ATOM   814  N N   . ALA   A 1 188 ? 163.559 159.606 161.327 1.00 98.70  ? 177 ALA   A N   1 
ATOM   815  C CA  . ALA   A 1 188 ? 162.877 158.350 161.625 1.00 98.47  ? 177 ALA   A CA  1 
ATOM   816  C C   . ALA   A 1 188 ? 163.861 157.189 161.684 1.00 104.22 ? 177 ALA   A C   1 
ATOM   817  O O   . ALA   A 1 188 ? 163.898 156.442 162.667 1.00 100.00 ? 177 ALA   A O   1 
ATOM   818  C CB  . ALA   A 1 188 ? 161.792 158.084 160.583 1.00 87.77  ? 177 ALA   A CB  1 
ATOM   819  N N   . LEU   A 1 189 ? 164.677 157.028 160.641 1.00 105.54 ? 178 LEU   A N   1 
ATOM   820  C CA  . LEU   A 1 189 ? 165.641 155.932 160.625 1.00 107.35 ? 178 LEU   A CA  1 
ATOM   821  C C   . LEU   A 1 189 ? 166.688 156.089 161.719 1.00 112.54 ? 178 LEU   A C   1 
ATOM   822  O O   . LEU   A 1 189 ? 167.239 155.090 162.196 1.00 113.46 ? 178 LEU   A O   1 
ATOM   823  C CB  . LEU   A 1 189 ? 166.313 155.843 159.255 1.00 105.83 ? 178 LEU   A CB  1 
ATOM   824  N N   . ASP   A 1 190 ? 166.977 157.327 162.125 1.00 110.74 ? 179 ASP   A N   1 
ATOM   825  C CA  . ASP   A 1 190 ? 167.965 157.548 163.175 1.00 108.84 ? 179 ASP   A CA  1 
ATOM   826  C C   . ASP   A 1 190 ? 167.412 157.188 164.550 1.00 110.68 ? 179 ASP   A C   1 
ATOM   827  O O   . ASP   A 1 190 ? 168.116 156.585 165.368 1.00 111.30 ? 179 ASP   A O   1 
ATOM   828  C CB  . ASP   A 1 190 ? 168.438 159.001 163.151 1.00 105.81 ? 179 ASP   A CB  1 
ATOM   829  N N   . PHE   A 1 191 ? 166.157 157.547 164.824 1.00 111.73 ? 180 PHE   A N   1 
ATOM   830  C CA  . PHE   A 1 191 ? 165.584 157.378 166.153 1.00 113.05 ? 180 PHE   A CA  1 
ATOM   831  C C   . PHE   A 1 191 ? 164.743 156.117 166.309 1.00 111.30 ? 180 PHE   A C   1 
ATOM   832  O O   . PHE   A 1 191 ? 164.321 155.815 167.430 1.00 111.82 ? 180 PHE   A O   1 
ATOM   833  C CB  . PHE   A 1 191 ? 164.733 158.599 166.524 1.00 112.15 ? 180 PHE   A CB  1 
ATOM   834  C CG  . PHE   A 1 191 ? 164.958 159.088 167.926 1.00 113.95 ? 180 PHE   A CG  1 
ATOM   835  C CD1 . PHE   A 1 191 ? 165.982 159.977 168.209 1.00 114.76 ? 180 PHE   A CD1 1 
ATOM   836  C CD2 . PHE   A 1 191 ? 164.147 158.656 168.962 1.00 116.03 ? 180 PHE   A CD2 1 
ATOM   837  C CE1 . PHE   A 1 191 ? 166.192 160.427 169.499 1.00 118.92 ? 180 PHE   A CE1 1 
ATOM   838  C CE2 . PHE   A 1 191 ? 164.351 159.103 170.255 1.00 118.74 ? 180 PHE   A CE2 1 
ATOM   839  C CZ  . PHE   A 1 191 ? 165.375 159.990 170.523 1.00 118.97 ? 180 PHE   A CZ  1 
ATOM   840  N N   . ARG   A 1 192 ? 164.488 155.376 165.232 1.00 105.55 ? 181 ARG   A N   1 
ATOM   841  C CA  . ARG   A 1 192 ? 163.735 154.125 165.313 1.00 102.54 ? 181 ARG   A CA  1 
ATOM   842  C C   . ARG   A 1 192 ? 164.642 152.910 165.179 1.00 106.19 ? 181 ARG   A C   1 
ATOM   843  O O   . ARG   A 1 192 ? 164.254 151.888 164.604 1.00 101.91 ? 181 ARG   A O   1 
ATOM   844  C CB  . ARG   A 1 192 ? 162.631 154.091 164.261 1.00 93.32  ? 181 ARG   A CB  1 
ATOM   845  C CG  . ARG   A 1 192 ? 161.548 155.138 164.462 1.00 82.20  ? 181 ARG   A CG  1 
ATOM   846  C CD  . ARG   A 1 192 ? 160.728 155.318 163.199 1.00 73.71  ? 181 ARG   A CD  1 
ATOM   847  N NE  . ARG   A 1 192 ? 160.045 154.086 162.823 1.00 68.78  ? 181 ARG   A NE  1 
ATOM   848  C CZ  . ARG   A 1 192 ? 160.056 153.564 161.604 1.00 65.44  ? 181 ARG   A CZ  1 
ATOM   849  N NH1 . ARG   A 1 192 ? 160.704 154.146 160.609 1.00 66.88  ? 181 ARG   A NH1 1 
ATOM   850  N NH2 . ARG   A 1 192 ? 159.395 152.433 161.377 1.00 63.91  ? 181 ARG   A NH2 1 
ATOM   851  N N   . THR   A 1 193 ? 165.862 153.006 165.699 1.00 111.28 ? 182 THR   A N   1 
ATOM   852  C CA  . THR   A 1 193 ? 166.746 151.857 165.759 1.00 112.92 ? 182 THR   A CA  1 
ATOM   853  C C   . THR   A 1 193 ? 166.120 150.774 166.639 1.00 109.64 ? 182 THR   A C   1 
ATOM   854  O O   . THR   A 1 193 ? 165.529 151.076 167.678 1.00 107.03 ? 182 THR   A O   1 
ATOM   855  C CB  . THR   A 1 193 ? 168.113 152.276 166.306 1.00 113.67 ? 182 THR   A CB  1 
ATOM   856  O OG1 . THR   A 1 193 ? 168.896 152.848 165.250 1.00 112.24 ? 182 THR   A OG1 1 
ATOM   857  C CG2 . THR   A 1 193 ? 168.869 151.098 166.910 1.00 111.27 ? 182 THR   A CG2 1 
ATOM   858  N N   . PRO   A 1 194 ? 166.216 149.503 166.231 1.00 108.76 ? 183 PRO   A N   1 
ATOM   859  C CA  . PRO   A 1 194 ? 165.586 148.434 167.025 1.00 107.30 ? 183 PRO   A CA  1 
ATOM   860  C C   . PRO   A 1 194 ? 166.053 148.392 168.469 1.00 108.80 ? 183 PRO   A C   1 
ATOM   861  O O   . PRO   A 1 194 ? 165.276 147.997 169.347 1.00 106.61 ? 183 PRO   A O   1 
ATOM   862  C CB  . PRO   A 1 194 ? 165.972 147.155 166.265 1.00 104.14 ? 183 PRO   A CB  1 
ATOM   863  C CG  . PRO   A 1 194 ? 167.087 147.560 165.339 1.00 108.80 ? 183 PRO   A CG  1 
ATOM   864  C CD  . PRO   A 1 194 ? 166.809 148.983 164.989 1.00 108.78 ? 183 PRO   A CD  1 
ATOM   865  N N   . ARG   A 1 195 ? 167.296 148.792 168.746 1.00 110.97 ? 184 ARG   A N   1 
ATOM   866  C CA  . ARG   A 1 195 ? 167.735 148.915 170.132 1.00 112.08 ? 184 ARG   A CA  1 
ATOM   867  C C   . ARG   A 1 195 ? 166.919 149.969 170.871 1.00 111.63 ? 184 ARG   A C   1 
ATOM   868  O O   . ARG   A 1 195 ? 166.537 149.772 172.031 1.00 110.17 ? 184 ARG   A O   1 
ATOM   869  C CB  . ARG   A 1 195 ? 169.225 149.252 170.185 1.00 113.37 ? 184 ARG   A CB  1 
ATOM   870  N N   . ASN   A 1 196 ? 166.636 151.084 170.191 1.00 110.22 ? 185 ASN   A N   1 
ATOM   871  C CA  . ASN   A 1 196 ? 165.776 152.129 170.811 1.00 109.72 ? 185 ASN   A CA  1 
ATOM   872  C C   . ASN   A 1 196 ? 164.402 151.515 171.089 1.00 107.24 ? 185 ASN   A C   1 
ATOM   873  O O   . ASN   A 1 196 ? 163.870 151.728 172.193 1.00 106.99 ? 185 ASN   A O   1 
ATOM   874  C CB  . ASN   A 1 196 ? 165.656 153.373 169.938 1.00 109.18 ? 185 ASN   A CB  1 
ATOM   875  C CG  . ASN   A 1 196 ? 166.981 153.801 169.356 1.00 111.73 ? 185 ASN   A CG  1 
ATOM   876  O OD1 . ASN   A 1 196 ? 168.031 153.269 169.734 1.00 114.35 ? 185 ASN   A OD1 1 
ATOM   877  N ND2 . ASN   A 1 196 ? 166.956 154.760 168.442 1.00 111.52 ? 185 ASN   A ND2 1 
ATOM   878  N N   . ALA   A 1 197 ? 163.853 150.777 170.120 1.00 102.60 ? 186 ALA   A N   1 
ATOM   879  C CA  . ALA   A 1 197 ? 162.531 150.187 170.307 1.00 96.61  ? 186 ALA   A CA  1 
ATOM   880  C C   . ALA   A 1 197 ? 162.517 149.227 171.491 1.00 101.39 ? 186 ALA   A C   1 
ATOM   881  O O   . ALA   A 1 197 ? 161.543 149.180 172.249 1.00 99.46  ? 186 ALA   A O   1 
ATOM   882  C CB  . ALA   A 1 197 ? 162.087 149.478 169.029 1.00 88.61  ? 186 ALA   A CB  1 
ATOM   883  N N   . LYS   A 1 198 ? 163.589 148.451 171.665 1.00 104.46 ? 187 LYS   A N   1 
ATOM   884  C CA  . LYS   A 1 198 ? 163.692 147.595 172.843 1.00 102.71 ? 187 LYS   A CA  1 
ATOM   885  C C   . LYS   A 1 198 ? 163.779 148.424 174.119 1.00 101.79 ? 187 LYS   A C   1 
ATOM   886  O O   . LYS   A 1 198 ? 163.235 148.035 175.159 1.00 100.12 ? 187 LYS   A O   1 
ATOM   887  C CB  . LYS   A 1 198 ? 164.899 146.666 172.720 1.00 103.09 ? 187 LYS   A CB  1 
ATOM   888  C CG  . LYS   A 1 198 ? 164.829 145.709 171.541 1.00 105.13 ? 187 LYS   A CG  1 
ATOM   889  C CD  . LYS   A 1 198 ? 166.214 145.404 170.993 1.00 109.89 ? 187 LYS   A CD  1 
ATOM   890  C CE  . LYS   A 1 198 ? 166.190 144.196 170.071 1.00 107.35 ? 187 LYS   A CE  1 
ATOM   891  N NZ  . LYS   A 1 198 ? 167.244 144.278 169.022 1.00 104.93 ? 187 LYS   A NZ  1 
ATOM   892  N N   . ILE   A 1 199 ? 164.467 149.566 174.061 1.00 102.71 ? 188 ILE   A N   1 
ATOM   893  C CA  . ILE   A 1 199 ? 164.536 150.458 175.217 1.00 104.01 ? 188 ILE   A CA  1 
ATOM   894  C C   . ILE   A 1 199 ? 163.145 150.964 175.581 1.00 102.20 ? 188 ILE   A C   1 
ATOM   895  O O   . ILE   A 1 199 ? 162.763 150.992 176.759 1.00 100.94 ? 188 ILE   A O   1 
ATOM   896  C CB  . ILE   A 1 199 ? 165.509 151.618 174.938 1.00 105.39 ? 188 ILE   A CB  1 
ATOM   897  C CG1 . ILE   A 1 199 ? 166.955 151.121 174.974 1.00 103.70 ? 188 ILE   A CG1 1 
ATOM   898  C CG2 . ILE   A 1 199 ? 165.304 152.747 175.939 1.00 105.23 ? 188 ILE   A CG2 1 
ATOM   899  C CD1 . ILE   A 1 199 ? 167.932 152.030 174.263 1.00 102.04 ? 188 ILE   A CD1 1 
ATOM   900  N N   . ILE   A 1 200 ? 162.363 151.370 174.577 1.00 99.62  ? 189 ILE   A N   1 
ATOM   901  C CA  . ILE   A 1 200 ? 160.983 151.789 174.823 1.00 97.29  ? 189 ILE   A CA  1 
ATOM   902  C C   . ILE   A 1 200 ? 160.111 150.652 175.329 1.00 94.30  ? 189 ILE   A C   1 
ATOM   903  O O   . ILE   A 1 200 ? 159.234 150.885 176.167 1.00 92.17  ? 189 ILE   A O   1 
ATOM   904  C CB  . ILE   A 1 200 ? 160.330 152.401 173.569 1.00 90.56  ? 189 ILE   A CB  1 
ATOM   905  C CG1 . ILE   A 1 200 ? 161.267 153.410 172.908 1.00 93.88  ? 189 ILE   A CG1 1 
ATOM   906  C CG2 . ILE   A 1 200 ? 159.036 153.094 173.932 1.00 85.18  ? 189 ILE   A CG2 1 
ATOM   907  C CD1 . ILE   A 1 200 ? 160.632 154.182 171.771 1.00 89.24  ? 189 ILE   A CD1 1 
ATOM   908  N N   . ASN   A 1 201 ? 160.328 149.425 174.853 1.00 91.75  ? 190 ASN   A N   1 
ATOM   909  C CA  . ASN   A 1 201 ? 159.610 148.276 175.398 1.00 92.28  ? 190 ASN   A CA  1 
ATOM   910  C C   . ASN   A 1 201 ? 159.946 148.055 176.869 1.00 92.01  ? 190 ASN   A C   1 
ATOM   911  O O   . ASN   A 1 201 ? 159.060 147.753 177.677 1.00 85.18  ? 190 ASN   A O   1 
ATOM   912  C CB  . ASN   A 1 201 ? 159.934 147.022 174.586 1.00 89.77  ? 190 ASN   A CB  1 
ATOM   913  C CG  . ASN   A 1 201 ? 158.784 146.585 173.704 1.00 84.97  ? 190 ASN   A CG  1 
ATOM   914  O OD1 . ASN   A 1 201 ? 157.753 147.254 173.632 1.00 84.28  ? 190 ASN   A OD1 1 
ATOM   915  N ND2 . ASN   A 1 201 ? 158.954 145.456 173.027 1.00 79.25  ? 190 ASN   A ND2 1 
ATOM   916  N N   . VAL   A 1 202 ? 161.221 148.200 177.231 1.00 96.03  ? 191 VAL   A N   1 
ATOM   917  C CA  . VAL   A 1 202 ? 161.621 148.074 178.631 1.00 92.70  ? 191 VAL   A CA  1 
ATOM   918  C C   . VAL   A 1 202 ? 160.967 149.169 179.466 1.00 88.84  ? 191 VAL   A C   1 
ATOM   919  O O   . VAL   A 1 202 ? 160.509 148.930 180.590 1.00 88.43  ? 191 VAL   A O   1 
ATOM   920  C CB  . VAL   A 1 202 ? 163.155 148.104 178.754 1.00 97.71  ? 191 VAL   A CB  1 
ATOM   921  C CG1 . VAL   A 1 202 ? 163.576 148.268 180.208 1.00 98.36  ? 191 VAL   A CG1 1 
ATOM   922  C CG2 . VAL   A 1 202 ? 163.756 146.838 178.161 1.00 99.83  ? 191 VAL   A CG2 1 
ATOM   923  N N   . CYS   A 1 203 ? 160.921 150.390 178.928 1.00 86.00  ? 192 CYS   A N   1 
ATOM   924  C CA  . CYS   A 1 203 ? 160.242 151.481 179.623 1.00 86.67  ? 192 CYS   A CA  1 
ATOM   925  C C   . CYS   A 1 203 ? 158.761 151.174 179.807 1.00 84.86  ? 192 CYS   A C   1 
ATOM   926  O O   . CYS   A 1 203 ? 158.181 151.477 180.856 1.00 83.73  ? 192 CYS   A O   1 
ATOM   927  C CB  . CYS   A 1 203 ? 160.430 152.790 178.857 1.00 89.18  ? 192 CYS   A CB  1 
ATOM   928  S SG  . CYS   A 1 203 ? 162.110 153.454 178.916 1.00 113.75 ? 192 CYS   A SG  1 
ATOM   929  N N   . ASN   A 1 204 ? 158.132 150.585 178.788 1.00 82.65  ? 193 ASN   A N   1 
ATOM   930  C CA  . ASN   A 1 204 ? 156.753 150.122 178.903 1.00 73.91  ? 193 ASN   A CA  1 
ATOM   931  C C   . ASN   A 1 204 ? 156.615 149.129 180.049 1.00 70.37  ? 193 ASN   A C   1 
ATOM   932  O O   . ASN   A 1 204 ? 155.683 149.215 180.856 1.00 69.52  ? 193 ASN   A O   1 
ATOM   933  C CB  . ASN   A 1 204 ? 156.319 149.494 177.573 1.00 70.81  ? 193 ASN   A CB  1 
ATOM   934  C CG  . ASN   A 1 204 ? 154.926 148.869 177.619 1.00 58.22  ? 193 ASN   A CG  1 
ATOM   935  O OD1 . ASN   A 1 204 ? 154.234 148.898 178.635 1.00 51.54  ? 193 ASN   A OD1 1 
ATOM   936  N ND2 . ASN   A 1 204 ? 154.513 148.294 176.496 1.00 54.15  ? 193 ASN   A ND2 1 
ATOM   937  N N   . TRP   A 1 205 ? 157.540 148.172 180.130 1.00 73.01  ? 194 TRP   A N   1 
ATOM   938  C CA  . TRP   A 1 205 ? 157.467 147.170 181.188 1.00 77.52  ? 194 TRP   A CA  1 
ATOM   939  C C   . TRP   A 1 205 ? 157.601 147.810 182.566 1.00 78.38  ? 194 TRP   A C   1 
ATOM   940  O O   . TRP   A 1 205 ? 156.870 147.452 183.496 1.00 75.87  ? 194 TRP   A O   1 
ATOM   941  C CB  . TRP   A 1 205 ? 158.538 146.101 180.976 1.00 78.08  ? 194 TRP   A CB  1 
ATOM   942  C CG  . TRP   A 1 205 ? 158.133 145.054 179.984 1.00 77.21  ? 194 TRP   A CG  1 
ATOM   943  C CD1 . TRP   A 1 205 ? 158.519 144.968 178.679 1.00 78.87  ? 194 TRP   A CD1 1 
ATOM   944  C CD2 . TRP   A 1 205 ? 157.250 143.949 180.215 1.00 78.12  ? 194 TRP   A CD2 1 
ATOM   945  N NE1 . TRP   A 1 205 ? 157.937 143.875 178.084 1.00 82.65  ? 194 TRP   A NE1 1 
ATOM   946  C CE2 . TRP   A 1 205 ? 157.153 143.233 179.005 1.00 77.32  ? 194 TRP   A CE2 1 
ATOM   947  C CE3 . TRP   A 1 205 ? 156.536 143.494 181.327 1.00 75.90  ? 194 TRP   A CE3 1 
ATOM   948  C CZ2 . TRP   A 1 205 ? 156.371 142.087 178.877 1.00 69.03  ? 194 TRP   A CZ2 1 
ATOM   949  C CZ3 . TRP   A 1 205 ? 155.760 142.356 181.197 1.00 70.10  ? 194 TRP   A CZ3 1 
ATOM   950  C CH2 . TRP   A 1 205 ? 155.683 141.666 179.981 1.00 68.32  ? 194 TRP   A CH2 1 
ATOM   951  N N   . ILE   A 1 206 ? 158.521 148.765 182.714 1.00 76.48  ? 195 ILE   A N   1 
ATOM   952  C CA  . ILE   A 1 206 ? 158.699 149.433 184.004 1.00 74.05  ? 195 ILE   A CA  1 
ATOM   953  C C   . ILE   A 1 206 ? 157.460 150.247 184.367 1.00 73.29  ? 195 ILE   A C   1 
ATOM   954  O O   . ILE   A 1 206 ? 157.015 150.249 185.522 1.00 73.11  ? 195 ILE   A O   1 
ATOM   955  C CB  . ILE   A 1 206 ? 159.965 150.308 183.999 1.00 81.17  ? 195 ILE   A CB  1 
ATOM   956  C CG1 . ILE   A 1 206 ? 161.172 149.513 183.501 1.00 80.80  ? 195 ILE   A CG1 1 
ATOM   957  C CG2 . ILE   A 1 206 ? 160.235 150.866 185.389 1.00 85.16  ? 195 ILE   A CG2 1 
ATOM   958  C CD1 . ILE   A 1 206 ? 162.457 150.311 183.472 1.00 88.04  ? 195 ILE   A CD1 1 
ATOM   959  N N   . LEU   A 1 207 ? 156.894 150.964 183.394 1.00 72.17  ? 196 LEU   A N   1 
ATOM   960  C CA  . LEU   A 1 207 ? 155.711 151.773 183.672 1.00 69.99  ? 196 LEU   A CA  1 
ATOM   961  C C   . LEU   A 1 207 ? 154.529 150.889 184.050 1.00 66.26  ? 196 LEU   A C   1 
ATOM   962  O O   . LEU   A 1 207 ? 153.740 151.238 184.936 1.00 64.42  ? 196 LEU   A O   1 
ATOM   963  C CB  . LEU   A 1 207 ? 155.380 152.646 182.461 1.00 68.45  ? 196 LEU   A CB  1 
ATOM   964  C CG  . LEU   A 1 207 ? 154.721 154.014 182.684 1.00 70.33  ? 196 LEU   A CG  1 
ATOM   965  C CD1 . LEU   A 1 207 ? 154.707 154.804 181.382 1.00 66.69  ? 196 LEU   A CD1 1 
ATOM   966  C CD2 . LEU   A 1 207 ? 153.313 153.908 183.254 1.00 67.52  ? 196 LEU   A CD2 1 
ATOM   967  N N   . SER   A 1 208 ? 154.392 149.738 183.388 1.00 64.70  ? 197 SER   A N   1 
ATOM   968  C CA  . SER   A 1 208 ? 153.367 148.776 183.773 1.00 62.54  ? 197 SER   A CA  1 
ATOM   969  C C   . SER   A 1 208 ? 153.613 148.251 185.181 1.00 64.75  ? 197 SER   A C   1 
ATOM   970  O O   . SER   A 1 208 ? 152.674 148.108 185.974 1.00 64.64  ? 197 SER   A O   1 
ATOM   971  C CB  . SER   A 1 208 ? 153.333 147.624 182.769 1.00 62.32  ? 197 SER   A CB  1 
ATOM   972  O OG  . SER   A 1 208 ? 153.239 148.110 181.441 1.00 56.95  ? 197 SER   A OG  1 
ATOM   973  N N   . SER   A 1 209 ? 154.875 147.962 185.508 1.00 68.31  ? 198 SER   A N   1 
ATOM   974  C CA  . SER   A 1 209 ? 155.220 147.509 186.850 1.00 72.57  ? 198 SER   A CA  1 
ATOM   975  C C   . SER   A 1 209 ? 154.844 148.541 187.901 1.00 67.92  ? 198 SER   A C   1 
ATOM   976  O O   . SER   A 1 209 ? 154.409 148.178 188.998 1.00 65.62  ? 198 SER   A O   1 
ATOM   977  C CB  . SER   A 1 209 ? 156.715 147.200 186.927 1.00 77.95  ? 198 SER   A CB  1 
ATOM   978  O OG  . SER   A 1 209 ? 157.080 146.203 185.989 1.00 78.69  ? 198 SER   A OG  1 
ATOM   979  N N   . ALA   A 1 210 ? 154.986 149.827 187.574 1.00 66.44  ? 199 ALA   A N   1 
ATOM   980  C CA  . ALA   A 1 210 ? 154.741 150.885 188.548 1.00 66.20  ? 199 ALA   A CA  1 
ATOM   981  C C   . ALA   A 1 210 ? 153.320 150.861 189.099 1.00 67.36  ? 199 ALA   A C   1 
ATOM   982  O O   . ALA   A 1 210 ? 153.079 151.410 190.179 1.00 71.06  ? 199 ALA   A O   1 
ATOM   983  C CB  . ALA   A 1 210 ? 155.032 152.251 187.925 1.00 64.59  ? 199 ALA   A CB  1 
ATOM   984  N N   . ILE   A 1 211 ? 152.376 150.246 188.388 1.00 66.44  ? 200 ILE   A N   1 
ATOM   985  C CA  . ILE   A 1 211 ? 151.013 150.077 188.875 1.00 61.75  ? 200 ILE   A CA  1 
ATOM   986  C C   . ILE   A 1 211 ? 150.611 148.617 188.997 1.00 64.73  ? 200 ILE   A C   1 
ATOM   987  O O   . ILE   A 1 211 ? 149.507 148.330 189.470 1.00 64.80  ? 200 ILE   A O   1 
ATOM   988  C CB  . ILE   A 1 211 ? 150.000 150.833 187.991 1.00 58.67  ? 200 ILE   A CB  1 
ATOM   989  N N   . GLY   A 1 212 ? 151.464 147.685 188.577 1.00 68.77  ? 201 GLY   A N   1 
ATOM   990  C CA  . GLY   A 1 212 ? 151.163 146.276 188.734 1.00 72.37  ? 201 GLY   A CA  1 
ATOM   991  C C   . GLY   A 1 212 ? 151.759 145.648 189.978 1.00 77.80  ? 201 GLY   A C   1 
ATOM   992  O O   . GLY   A 1 212 ? 151.159 144.742 190.564 1.00 72.98  ? 201 GLY   A O   1 
ATOM   993  N N   . LEU   A 1 213 ? 152.942 146.113 190.386 1.00 80.93  ? 202 LEU   A N   1 
ATOM   994  C CA  . LEU   A 1 213 ? 153.588 145.546 191.567 1.00 82.27  ? 202 LEU   A CA  1 
ATOM   995  C C   . LEU   A 1 213 ? 152.764 145.681 192.847 1.00 80.99  ? 202 LEU   A C   1 
ATOM   996  O O   . LEU   A 1 213 ? 152.798 144.739 193.658 1.00 84.61  ? 202 LEU   A O   1 
ATOM   997  C CB  . LEU   A 1 213 ? 154.998 146.137 191.742 1.00 78.09  ? 202 LEU   A CB  1 
ATOM   998  C CG  . LEU   A 1 213 ? 155.319 147.617 191.976 1.00 67.31  ? 202 LEU   A CG  1 
ATOM   999  C CD1 . LEU   A 1 213 ? 155.271 147.965 193.458 1.00 72.33  ? 202 LEU   A CD1 1 
ATOM   1000 C CD2 . LEU   A 1 213 ? 156.675 147.970 191.386 1.00 64.99  ? 202 LEU   A CD2 1 
ATOM   1001 N N   . PRO   A 1 214 ? 152.040 146.780 193.115 1.00 77.33  ? 203 PRO   A N   1 
ATOM   1002 C CA  . PRO   A 1 214 ? 151.188 146.783 194.316 1.00 79.75  ? 203 PRO   A CA  1 
ATOM   1003 C C   . PRO   A 1 214 ? 150.159 145.671 194.309 1.00 83.96  ? 203 PRO   A C   1 
ATOM   1004 O O   . PRO   A 1 214 ? 149.844 145.118 195.370 1.00 93.86  ? 203 PRO   A O   1 
ATOM   1005 C CB  . PRO   A 1 214 ? 150.522 148.166 194.280 1.00 83.21  ? 203 PRO   A CB  1 
ATOM   1006 C CG  . PRO   A 1 214 ? 151.384 148.990 193.414 1.00 81.02  ? 203 PRO   A CG  1 
ATOM   1007 C CD  . PRO   A 1 214 ? 151.918 148.055 192.383 1.00 79.01  ? 203 PRO   A CD  1 
ATOM   1008 N N   . VAL   A 1 215 ? 149.628 145.323 193.136 1.00 77.38  ? 204 VAL   A N   1 
ATOM   1009 C CA  . VAL   A 1 215 ? 148.692 144.207 193.042 1.00 84.03  ? 204 VAL   A CA  1 
ATOM   1010 C C   . VAL   A 1 215 ? 149.406 142.897 193.349 1.00 88.45  ? 204 VAL   A C   1 
ATOM   1011 O O   . VAL   A 1 215 ? 148.826 141.972 193.929 1.00 79.91  ? 204 VAL   A O   1 
ATOM   1012 C CB  . VAL   A 1 215 ? 148.030 144.181 191.654 1.00 73.27  ? 204 VAL   A CB  1 
ATOM   1013 C CG1 . VAL   A 1 215 ? 146.725 143.418 191.709 1.00 66.09  ? 204 VAL   A CG1 1 
ATOM   1014 C CG2 . VAL   A 1 215 ? 147.808 145.596 191.148 1.00 73.64  ? 204 VAL   A CG2 1 
ATOM   1015 N N   . MET   A 1 216 ? 150.677 142.798 192.952 1.00 88.60  ? 205 MET   A N   1 
ATOM   1016 C CA  . MET   A 1 216 ? 151.460 141.602 193.246 1.00 86.86  ? 205 MET   A CA  1 
ATOM   1017 C C   . MET   A 1 216 ? 151.646 141.415 194.747 1.00 90.26  ? 205 MET   A C   1 
ATOM   1018 O O   . MET   A 1 216 ? 151.607 140.286 195.250 1.00 90.75  ? 205 MET   A O   1 
ATOM   1019 C CB  . MET   A 1 216 ? 152.816 141.678 192.543 1.00 88.57  ? 205 MET   A CB  1 
ATOM   1020 C CG  . MET   A 1 216 ? 153.517 140.336 192.387 1.00 96.63  ? 205 MET   A CG  1 
ATOM   1021 S SD  . MET   A 1 216 ? 155.147 140.443 191.614 1.00 120.63 ? 205 MET   A SD  1 
ATOM   1022 C CE  . MET   A 1 216 ? 155.292 142.203 191.311 1.00 84.85  ? 205 MET   A CE  1 
ATOM   1023 N N   . PHE   A 1 217 ? 151.853 142.512 195.479 1.00 92.82  ? 206 PHE   A N   1 
ATOM   1024 C CA  . PHE   A 1 217 ? 152.129 142.416 196.908 1.00 97.89  ? 206 PHE   A CA  1 
ATOM   1025 C C   . PHE   A 1 217 ? 150.864 142.359 197.756 1.00 95.50  ? 206 PHE   A C   1 
ATOM   1026 O O   . PHE   A 1 217 ? 150.891 141.766 198.839 1.00 96.68  ? 206 PHE   A O   1 
ATOM   1027 C CB  . PHE   A 1 217 ? 152.994 143.597 197.354 1.00 96.66  ? 206 PHE   A CB  1 
ATOM   1028 C CG  . PHE   A 1 217 ? 154.458 143.424 197.060 1.00 102.08 ? 206 PHE   A CG  1 
ATOM   1029 C CD1 . PHE   A 1 217 ? 154.916 142.315 196.368 1.00 102.37 ? 206 PHE   A CD1 1 
ATOM   1030 C CD2 . PHE   A 1 217 ? 155.376 144.374 197.476 1.00 102.53 ? 206 PHE   A CD2 1 
ATOM   1031 C CE1 . PHE   A 1 217 ? 156.262 142.156 196.098 1.00 100.13 ? 206 PHE   A CE1 1 
ATOM   1032 C CE2 . PHE   A 1 217 ? 156.723 144.220 197.209 1.00 99.47  ? 206 PHE   A CE2 1 
ATOM   1033 C CZ  . PHE   A 1 217 ? 157.166 143.110 196.519 1.00 100.04 ? 206 PHE   A CZ  1 
ATOM   1034 N N   . MET   A 1 218 ? 149.763 142.952 197.298 1.00 91.94  ? 207 MET   A N   1 
ATOM   1035 C CA  . MET   A 1 218 ? 148.541 143.024 198.088 1.00 91.70  ? 207 MET   A CA  1 
ATOM   1036 C C   . MET   A 1 218 ? 147.511 141.969 197.709 1.00 94.99  ? 207 MET   A C   1 
ATOM   1037 O O   . MET   A 1 218 ? 146.345 142.098 198.096 1.00 92.16  ? 207 MET   A O   1 
ATOM   1038 C CB  . MET   A 1 218 ? 147.916 144.419 197.973 1.00 92.67  ? 207 MET   A CB  1 
ATOM   1039 C CG  . MET   A 1 218 ? 148.850 145.551 198.365 1.00 99.52  ? 207 MET   A CG  1 
ATOM   1040 S SD  . MET   A 1 218 ? 149.892 145.136 199.776 1.00 115.91 ? 207 MET   A SD  1 
ATOM   1041 C CE  . MET   A 1 218 ? 150.665 146.718 200.104 1.00 105.63 ? 207 MET   A CE  1 
ATOM   1042 N N   . ALA   A 1 219 ? 147.900 140.939 196.964 1.00 98.90  ? 208 ALA   A N   1 
ATOM   1043 C CA  . ALA   A 1 219 ? 146.994 139.854 196.609 1.00 98.41  ? 208 ALA   A CA  1 
ATOM   1044 C C   . ALA   A 1 219 ? 147.299 138.641 197.479 1.00 100.81 ? 208 ALA   A C   1 
ATOM   1045 O O   . ALA   A 1 219 ? 148.460 138.237 197.602 1.00 99.88  ? 208 ALA   A O   1 
ATOM   1046 C CB  . ALA   A 1 219 ? 147.122 139.500 195.129 1.00 91.99  ? 208 ALA   A CB  1 
ATOM   1047 N N   . THR   A 1 220 ? 146.263 138.067 198.084 1.00 102.39 ? 209 THR   A N   1 
ATOM   1048 C CA  . THR   A 1 220 ? 146.432 136.876 198.905 1.00 109.79 ? 209 THR   A CA  1 
ATOM   1049 C C   . THR   A 1 220 ? 145.103 136.140 198.985 1.00 114.19 ? 209 THR   A C   1 
ATOM   1050 O O   . THR   A 1 220 ? 144.037 136.716 198.752 1.00 113.37 ? 209 THR   A O   1 
ATOM   1051 C CB  . THR   A 1 220 ? 146.947 137.222 200.308 1.00 111.92 ? 209 THR   A CB  1 
ATOM   1052 O OG1 . THR   A 1 220 ? 147.488 136.047 200.924 1.00 113.74 ? 209 THR   A OG1 1 
ATOM   1053 C CG2 . THR   A 1 220 ? 145.825 137.776 201.175 1.00 113.58 ? 209 THR   A CG2 1 
ATOM   1054 N N   . THR   A 1 221 ? 145.184 134.854 199.313 1.00 115.14 ? 210 THR   A N   1 
ATOM   1055 C CA  . THR   A 1 221 ? 143.996 134.022 199.416 1.00 115.23 ? 210 THR   A CA  1 
ATOM   1056 C C   . THR   A 1 221 ? 143.258 134.288 200.722 1.00 116.58 ? 210 THR   A C   1 
ATOM   1057 O O   . THR   A 1 221 ? 143.863 134.594 201.754 1.00 112.48 ? 210 THR   A O   1 
ATOM   1058 C CB  . THR   A 1 221 ? 144.363 132.541 199.322 1.00 114.29 ? 210 THR   A CB  1 
ATOM   1059 O OG1 . THR   A 1 221 ? 145.450 132.259 200.213 1.00 111.54 ? 210 THR   A OG1 1 
ATOM   1060 C CG2 . THR   A 1 221 ? 144.769 132.183 197.902 1.00 103.21 ? 210 THR   A CG2 1 
ATOM   1061 N N   . LYS   A 1 222 ? 141.935 134.168 200.666 1.00 120.45 ? 211 LYS   A N   1 
ATOM   1062 C CA  . LYS   A 1 222 ? 141.070 134.336 201.828 1.00 120.78 ? 211 LYS   A CA  1 
ATOM   1063 C C   . LYS   A 1 222 ? 140.445 132.990 202.165 1.00 117.81 ? 211 LYS   A C   1 
ATOM   1064 O O   . LYS   A 1 222 ? 139.792 132.375 201.315 1.00 117.04 ? 211 LYS   A O   1 
ATOM   1065 C CB  . LYS   A 1 222 ? 139.990 135.383 201.562 1.00 120.02 ? 211 LYS   A CB  1 
ATOM   1066 N N   . TYR   A 1 223 ? 140.643 132.537 203.403 1.00 116.00 ? 212 TYR   A N   1 
ATOM   1067 C CA  . TYR   A 1 223 ? 140.134 131.241 203.851 1.00 115.74 ? 212 TYR   A CA  1 
ATOM   1068 C C   . TYR   A 1 223 ? 138.688 131.415 204.308 1.00 119.09 ? 212 TYR   A C   1 
ATOM   1069 O O   . TYR   A 1 223 ? 138.374 131.469 205.500 1.00 118.00 ? 212 TYR   A O   1 
ATOM   1070 C CB  . TYR   A 1 223 ? 141.012 130.672 204.959 1.00 113.59 ? 212 TYR   A CB  1 
ATOM   1071 N N   . ARG   A 1 224 ? 137.792 131.504 203.329 1.00 121.56 ? 213 ARG   A N   1 
ATOM   1072 C CA  . ARG   A 1 224 ? 136.374 131.637 203.622 1.00 122.88 ? 213 ARG   A CA  1 
ATOM   1073 C C   . ARG   A 1 224 ? 135.822 130.337 204.202 1.00 125.80 ? 213 ARG   A C   1 
ATOM   1074 O O   . ARG   A 1 224 ? 136.403 129.258 204.050 1.00 125.57 ? 213 ARG   A O   1 
ATOM   1075 C CB  . ARG   A 1 224 ? 135.599 132.023 202.362 1.00 122.43 ? 213 ARG   A CB  1 
ATOM   1076 N N   . GLN   A 1 225 ? 134.681 130.457 204.885 1.00 127.02 ? 214 GLN   A N   1 
ATOM   1077 C CA  . GLN   A 1 225 ? 134.066 129.290 205.510 1.00 127.85 ? 214 GLN   A CA  1 
ATOM   1078 C C   . GLN   A 1 225 ? 133.659 128.254 204.470 1.00 129.17 ? 214 GLN   A C   1 
ATOM   1079 O O   . GLN   A 1 225 ? 133.848 127.049 204.675 1.00 132.34 ? 214 GLN   A O   1 
ATOM   1080 C CB  . GLN   A 1 225 ? 132.859 129.716 206.344 1.00 123.96 ? 214 GLN   A CB  1 
ATOM   1081 N N   . GLY   A 1 226 ? 133.098 128.701 203.349 1.00 128.13 ? 215 GLY   A N   1 
ATOM   1082 C CA  . GLY   A 1 226 ? 132.690 127.793 202.297 1.00 127.58 ? 215 GLY   A CA  1 
ATOM   1083 C C   . GLY   A 1 226 ? 133.858 127.143 201.586 1.00 128.50 ? 215 GLY   A C   1 
ATOM   1084 O O   . GLY   A 1 226 ? 134.001 125.916 201.605 1.00 130.20 ? 215 GLY   A O   1 
ATOM   1085 N N   . SER   A 1 227 ? 134.702 127.955 200.955 1.00 127.55 ? 216 SER   A N   1 
ATOM   1086 C CA  . SER   A 1 227 ? 135.861 127.445 200.238 1.00 125.30 ? 216 SER   A CA  1 
ATOM   1087 C C   . SER   A 1 227 ? 136.903 128.548 200.133 1.00 124.28 ? 216 SER   A C   1 
ATOM   1088 O O   . SER   A 1 227 ? 136.585 129.734 200.247 1.00 124.50 ? 216 SER   A O   1 
ATOM   1089 C CB  . SER   A 1 227 ? 135.480 126.935 198.844 1.00 118.60 ? 216 SER   A CB  1 
ATOM   1090 N N   . ILE   A 1 228 ? 138.155 128.139 199.914 1.00 124.00 ? 217 ILE   A N   1 
ATOM   1091 C CA  . ILE   A 1 228 ? 139.236 129.104 199.773 1.00 122.26 ? 217 ILE   A CA  1 
ATOM   1092 C C   . ILE   A 1 228 ? 139.105 129.826 198.439 1.00 119.15 ? 217 ILE   A C   1 
ATOM   1093 O O   . ILE   A 1 228 ? 138.947 129.202 197.382 1.00 118.55 ? 217 ILE   A O   1 
ATOM   1094 C CB  . ILE   A 1 228 ? 140.599 128.404 199.900 1.00 119.55 ? 217 ILE   A CB  1 
ATOM   1095 C CG1 . ILE   A 1 228 ? 140.836 127.960 201.345 1.00 120.67 ? 217 ILE   A CG1 1 
ATOM   1096 C CG2 . ILE   A 1 228 ? 141.721 129.319 199.434 1.00 117.27 ? 217 ILE   A CG2 1 
ATOM   1097 C CD1 . ILE   A 1 228 ? 141.931 126.929 201.494 1.00 121.75 ? 217 ILE   A CD1 1 
ATOM   1098 N N   . ASP   A 1 229 ? 139.171 131.155 198.485 1.00 113.39 ? 218 ASP   A N   1 
ATOM   1099 C CA  . ASP   A 1 229 ? 139.033 131.986 197.300 1.00 112.38 ? 218 ASP   A CA  1 
ATOM   1100 C C   . ASP   A 1 229 ? 140.221 132.932 197.193 1.00 112.12 ? 218 ASP   A C   1 
ATOM   1101 O O   . ASP   A 1 229 ? 140.873 133.263 198.187 1.00 115.13 ? 218 ASP   A O   1 
ATOM   1102 C CB  . ASP   A 1 229 ? 137.723 132.786 197.323 1.00 114.13 ? 218 ASP   A CB  1 
ATOM   1103 N N   . CYS   A 1 230 ? 140.494 133.364 195.965 1.00 106.87 ? 219 CYS   A N   1 
ATOM   1104 C CA  . CYS   A 1 230 ? 141.594 134.272 195.663 1.00 101.15 ? 219 CYS   A CA  1 
ATOM   1105 C C   . CYS   A 1 230 ? 141.024 135.649 195.349 1.00 99.88  ? 219 CYS   A C   1 
ATOM   1106 O O   . CYS   A 1 230 ? 140.370 135.832 194.317 1.00 98.36  ? 219 CYS   A O   1 
ATOM   1107 C CB  . CYS   A 1 230 ? 142.423 133.747 194.491 1.00 95.00  ? 219 CYS   A CB  1 
ATOM   1108 S SG  . CYS   A 1 230 ? 143.536 134.959 193.748 1.00 78.22  ? 219 CYS   A SG  1 
ATOM   1109 N N   . THR   A 1 231 ? 141.275 136.610 196.236 1.00 100.43 ? 220 THR   A N   1 
ATOM   1110 C CA  . THR   A 1 231 ? 140.766 137.965 196.078 1.00 99.86  ? 220 THR   A CA  1 
ATOM   1111 C C   . THR   A 1 231 ? 141.857 138.955 196.460 1.00 97.90  ? 220 THR   A C   1 
ATOM   1112 O O   . THR   A 1 231 ? 142.864 138.597 197.075 1.00 96.07  ? 220 THR   A O   1 
ATOM   1113 C CB  . THR   A 1 231 ? 139.510 138.208 196.928 1.00 101.19 ? 220 THR   A CB  1 
ATOM   1114 O OG1 . THR   A 1 231 ? 139.785 137.885 198.297 1.00 104.49 ? 220 THR   A OG1 1 
ATOM   1115 C CG2 . THR   A 1 231 ? 138.341 137.368 196.431 1.00 96.12  ? 220 THR   A CG2 1 
ATOM   1116 N N   . LEU   A 1 232 ? 141.647 140.211 196.079 1.00 96.36  ? 221 LEU   A N   1 
ATOM   1117 C CA  . LEU   A 1 232 ? 142.572 141.274 196.436 1.00 94.58  ? 221 LEU   A CA  1 
ATOM   1118 C C   . LEU   A 1 232 ? 142.259 141.817 197.827 1.00 94.35  ? 221 LEU   A C   1 
ATOM   1119 O O   . LEU   A 1 232 ? 141.147 141.681 198.344 1.00 94.30  ? 221 LEU   A O   1 
ATOM   1120 C CB  . LEU   A 1 232 ? 142.518 142.406 195.412 1.00 89.03  ? 221 LEU   A CB  1 
ATOM   1121 C CG  . LEU   A 1 232 ? 143.453 142.272 194.211 1.00 86.59  ? 221 LEU   A CG  1 
ATOM   1122 C CD1 . LEU   A 1 232 ? 143.130 143.322 193.161 1.00 76.75  ? 221 LEU   A CD1 1 
ATOM   1123 C CD2 . LEU   A 1 232 ? 144.898 142.385 194.662 1.00 89.05  ? 221 LEU   A CD2 1 
ATOM   1124 N N   . THR   A 1 233 ? 143.266 142.443 198.432 1.00 90.67  ? 222 THR   A N   1 
ATOM   1125 C CA  . THR   A 1 233 ? 143.127 143.041 199.751 1.00 90.82  ? 222 THR   A CA  1 
ATOM   1126 C C   . THR   A 1 233 ? 143.740 144.433 199.739 1.00 92.68  ? 222 THR   A C   1 
ATOM   1127 O O   . THR   A 1 233 ? 144.730 144.685 199.047 1.00 95.24  ? 222 THR   A O   1 
ATOM   1128 C CB  . THR   A 1 233 ? 143.793 142.186 200.838 1.00 91.34  ? 222 THR   A CB  1 
ATOM   1129 N N   . PHE   A 1 234 ? 143.143 145.332 200.517 1.00 85.78  ? 223 PHE   A N   1 
ATOM   1130 C CA  . PHE   A 1 234 ? 143.620 146.704 200.608 1.00 84.04  ? 223 PHE   A CA  1 
ATOM   1131 C C   . PHE   A 1 234 ? 143.338 147.235 202.006 1.00 81.59  ? 223 PHE   A C   1 
ATOM   1132 O O   . PHE   A 1 234 ? 142.480 146.719 202.727 1.00 84.87  ? 223 PHE   A O   1 
ATOM   1133 C CB  . PHE   A 1 234 ? 142.966 147.603 199.551 1.00 86.47  ? 223 PHE   A CB  1 
ATOM   1134 C CG  . PHE   A 1 234 ? 143.419 147.320 198.148 1.00 82.28  ? 223 PHE   A CG  1 
ATOM   1135 C CD1 . PHE   A 1 234 ? 144.717 147.600 197.755 1.00 80.58  ? 223 PHE   A CD1 1 
ATOM   1136 C CD2 . PHE   A 1 234 ? 142.546 146.779 197.220 1.00 80.51  ? 223 PHE   A CD2 1 
ATOM   1137 C CE1 . PHE   A 1 234 ? 145.136 147.342 196.465 1.00 77.77  ? 223 PHE   A CE1 1 
ATOM   1138 C CE2 . PHE   A 1 234 ? 142.959 146.520 195.928 1.00 81.15  ? 223 PHE   A CE2 1 
ATOM   1139 C CZ  . PHE   A 1 234 ? 144.256 146.802 195.551 1.00 82.47  ? 223 PHE   A CZ  1 
ATOM   1140 N N   . SER   A 1 235 ? 144.075 148.276 202.380 1.00 80.02  ? 224 SER   A N   1 
ATOM   1141 C CA  . SER   A 1 235 ? 143.927 148.883 203.697 1.00 75.65  ? 224 SER   A CA  1 
ATOM   1142 C C   . SER   A 1 235 ? 143.137 150.185 203.620 1.00 77.57  ? 224 SER   A C   1 
ATOM   1143 O O   . SER   A 1 235 ? 142.955 150.749 202.541 1.00 80.76  ? 224 SER   A O   1 
ATOM   1144 C CB  . SER   A 1 235 ? 145.299 149.137 204.326 1.00 75.12  ? 224 SER   A CB  1 
ATOM   1145 N N   . THR   A 1 238 ? 140.121 149.823 202.687 1.00 78.88  ? 227 THR   A N   1 
ATOM   1146 C CA  . THR   A 1 238 ? 140.233 149.261 201.347 1.00 86.84  ? 227 THR   A CA  1 
ATOM   1147 C C   . THR   A 1 238 ? 139.469 150.107 200.335 1.00 91.65  ? 227 THR   A C   1 
ATOM   1148 O O   . THR   A 1 238 ? 139.798 150.122 199.147 1.00 95.59  ? 227 THR   A O   1 
ATOM   1149 C CB  . THR   A 1 238 ? 139.708 147.815 201.294 1.00 83.53  ? 227 THR   A CB  1 
ATOM   1150 N N   . TRP   A 1 239 ? 138.451 150.819 200.822 1.00 88.28  ? 228 TRP   A N   1 
ATOM   1151 C CA  . TRP   A 1 239 ? 137.594 151.618 199.955 1.00 85.92  ? 228 TRP   A CA  1 
ATOM   1152 C C   . TRP   A 1 239 ? 138.338 152.751 199.261 1.00 83.13  ? 228 TRP   A C   1 
ATOM   1153 O O   . TRP   A 1 239 ? 137.830 153.291 198.274 1.00 84.32  ? 228 TRP   A O   1 
ATOM   1154 C CB  . TRP   A 1 239 ? 136.425 152.194 200.758 1.00 84.03  ? 228 TRP   A CB  1 
ATOM   1155 N N   . TYR   A 1 240 ? 139.521 153.123 199.749 1.00 80.33  ? 229 TYR   A N   1 
ATOM   1156 C CA  . TYR   A 1 240 ? 140.288 154.199 199.129 1.00 86.76  ? 229 TYR   A CA  1 
ATOM   1157 C C   . TYR   A 1 240 ? 141.276 153.653 198.100 1.00 86.03  ? 229 TYR   A C   1 
ATOM   1158 O O   . TYR   A 1 240 ? 141.268 154.078 196.941 1.00 84.54  ? 229 TYR   A O   1 
ATOM   1159 C CB  . TYR   A 1 240 ? 141.007 155.020 200.207 1.00 89.82  ? 229 TYR   A CB  1 
ATOM   1160 C CG  . TYR   A 1 240 ? 142.025 156.004 199.671 1.00 90.81  ? 229 TYR   A CG  1 
ATOM   1161 C CD1 . TYR   A 1 240 ? 141.641 157.278 199.274 1.00 88.16  ? 229 TYR   A CD1 1 
ATOM   1162 C CD2 . TYR   A 1 240 ? 143.365 155.661 199.559 1.00 85.72  ? 229 TYR   A CD2 1 
ATOM   1163 C CE1 . TYR   A 1 240 ? 142.564 158.182 198.783 1.00 83.07  ? 229 TYR   A CE1 1 
ATOM   1164 C CE2 . TYR   A 1 240 ? 144.295 156.557 199.069 1.00 81.55  ? 229 TYR   A CE2 1 
ATOM   1165 C CZ  . TYR   A 1 240 ? 143.889 157.816 198.683 1.00 81.94  ? 229 TYR   A CZ  1 
ATOM   1166 O OH  . TYR   A 1 240 ? 144.813 158.712 198.194 1.00 88.01  ? 229 TYR   A OH  1 
ATOM   1167 N N   . TRP   A 1 241 ? 142.128 152.708 198.511 1.00 84.67  ? 230 TRP   A N   1 
ATOM   1168 C CA  . TRP   A 1 241 ? 143.119 152.154 197.592 1.00 85.79  ? 230 TRP   A CA  1 
ATOM   1169 C C   . TRP   A 1 241 ? 142.475 151.353 196.467 1.00 81.16  ? 230 TRP   A C   1 
ATOM   1170 O O   . TRP   A 1 241 ? 142.970 151.380 195.332 1.00 80.33  ? 230 TRP   A O   1 
ATOM   1171 C CB  . TRP   A 1 241 ? 144.119 151.281 198.349 1.00 87.59  ? 230 TRP   A CB  1 
ATOM   1172 C CG  . TRP   A 1 241 ? 145.330 152.024 198.819 1.00 93.92  ? 230 TRP   A CG  1 
ATOM   1173 C CD1 . TRP   A 1 241 ? 145.359 153.102 199.651 1.00 94.22  ? 230 TRP   A CD1 1 
ATOM   1174 C CD2 . TRP   A 1 241 ? 146.692 151.752 198.468 1.00 103.20 ? 230 TRP   A CD2 1 
ATOM   1175 N NE1 . TRP   A 1 241 ? 146.654 153.515 199.848 1.00 98.48  ? 230 TRP   A NE1 1 
ATOM   1176 C CE2 . TRP   A 1 241 ? 147.492 152.702 199.132 1.00 104.32 ? 230 TRP   A CE2 1 
ATOM   1177 C CE3 . TRP   A 1 241 ? 147.312 150.794 197.661 1.00 111.37 ? 230 TRP   A CE3 1 
ATOM   1178 C CZ2 . TRP   A 1 241 ? 148.880 152.723 199.014 1.00 107.82 ? 230 TRP   A CZ2 1 
ATOM   1179 C CZ3 . TRP   A 1 241 ? 148.690 150.816 197.544 1.00 117.21 ? 230 TRP   A CZ3 1 
ATOM   1180 C CH2 . TRP   A 1 241 ? 149.458 151.774 198.217 1.00 112.05 ? 230 TRP   A CH2 1 
ATOM   1181 N N   . GLU   A 1 242 ? 141.388 150.629 196.755 1.00 78.69  ? 231 GLU   A N   1 
ATOM   1182 C CA  . GLU   A 1 242 ? 140.736 149.842 195.716 1.00 74.70  ? 231 GLU   A CA  1 
ATOM   1183 C C   . GLU   A 1 242 ? 140.229 150.724 194.584 1.00 71.06  ? 231 GLU   A C   1 
ATOM   1184 O O   . GLU   A 1 242 ? 140.356 150.359 193.410 1.00 69.99  ? 231 GLU   A O   1 
ATOM   1185 C CB  . GLU   A 1 242 ? 139.587 149.030 196.313 1.00 76.21  ? 231 GLU   A CB  1 
ATOM   1186 N N   . ASN   A 1 243 ? 139.664 151.885 194.911 1.00 72.00  ? 232 ASN   A N   1 
ATOM   1187 C CA  . ASN   A 1 243 ? 139.232 152.828 193.889 1.00 73.71  ? 232 ASN   A CA  1 
ATOM   1188 C C   . ASN   A 1 243 ? 140.390 153.610 193.286 1.00 74.64  ? 232 ASN   A C   1 
ATOM   1189 O O   . ASN   A 1 243 ? 140.329 153.975 192.106 1.00 72.67  ? 232 ASN   A O   1 
ATOM   1190 C CB  . ASN   A 1 243 ? 138.201 153.800 194.467 1.00 73.83  ? 232 ASN   A CB  1 
ATOM   1191 C CG  . ASN   A 1 243 ? 136.779 153.427 194.096 1.00 74.14  ? 232 ASN   A CG  1 
ATOM   1192 O OD1 . ASN   A 1 243 ? 136.145 154.090 193.275 1.00 68.04  ? 232 ASN   A OD1 1 
ATOM   1193 N ND2 . ASN   A 1 243 ? 136.272 152.357 194.697 1.00 80.02  ? 232 ASN   A ND2 1 
ATOM   1194 N N   . LEU   A 1 244 ? 141.442 153.874 194.065 1.00 78.74  ? 233 LEU   A N   1 
ATOM   1195 C CA  . LEU   A 1 244 ? 142.599 154.582 193.528 1.00 74.30  ? 233 LEU   A CA  1 
ATOM   1196 C C   . LEU   A 1 244 ? 143.282 153.768 192.439 1.00 63.91  ? 233 LEU   A C   1 
ATOM   1197 O O   . LEU   A 1 244 ? 143.714 154.321 191.422 1.00 59.12  ? 233 LEU   A O   1 
ATOM   1198 C CB  . LEU   A 1 244 ? 143.584 154.909 194.649 1.00 76.66  ? 233 LEU   A CB  1 
ATOM   1199 C CG  . LEU   A 1 244 ? 144.845 155.680 194.251 1.00 75.83  ? 233 LEU   A CG  1 
ATOM   1200 C CD1 . LEU   A 1 244 ? 144.503 156.857 193.349 1.00 70.40  ? 233 LEU   A CD1 1 
ATOM   1201 C CD2 . LEU   A 1 244 ? 145.601 156.150 195.484 1.00 82.86  ? 233 LEU   A CD2 1 
ATOM   1202 N N   . LEU   A 1 245 ? 143.394 152.453 192.637 1.00 62.48  ? 234 LEU   A N   1 
ATOM   1203 C CA  . LEU   A 1 245 ? 143.984 151.604 191.606 1.00 58.42  ? 234 LEU   A CA  1 
ATOM   1204 C C   . LEU   A 1 245 ? 143.169 151.654 190.319 1.00 53.16  ? 234 LEU   A C   1 
ATOM   1205 O O   . LEU   A 1 245 ? 143.731 151.760 189.222 1.00 49.44  ? 234 LEU   A O   1 
ATOM   1206 C CB  . LEU   A 1 245 ? 144.100 150.165 192.109 1.00 59.65  ? 234 LEU   A CB  1 
ATOM   1207 C CG  . LEU   A 1 245 ? 144.427 149.101 191.058 1.00 49.07  ? 234 LEU   A CG  1 
ATOM   1208 C CD1 . LEU   A 1 245 ? 145.753 149.400 190.375 1.00 49.38  ? 234 LEU   A CD1 1 
ATOM   1209 C CD2 . LEU   A 1 245 ? 144.440 147.716 191.681 1.00 52.41  ? 234 LEU   A CD2 1 
ATOM   1210 N N   . LYS   A 1 246 ? 141.841 151.586 190.435 1.00 54.90  ? 235 LYS   A N   1 
ATOM   1211 C CA  . LYS   A 1 246 ? 140.988 151.630 189.251 1.00 53.04  ? 235 LYS   A CA  1 
ATOM   1212 C C   . LYS   A 1 246 ? 141.093 152.973 188.541 1.00 50.39  ? 235 LYS   A C   1 
ATOM   1213 O O   . LYS   A 1 246 ? 141.143 153.028 187.306 1.00 49.34  ? 235 LYS   A O   1 
ATOM   1214 C CB  . LYS   A 1 246 ? 139.541 151.335 189.644 1.00 56.82  ? 235 LYS   A CB  1 
ATOM   1215 C CG  . LYS   A 1 246 ? 139.367 150.019 190.384 1.00 62.26  ? 235 LYS   A CG  1 
ATOM   1216 C CD  . LYS   A 1 246 ? 138.053 149.967 191.145 1.00 63.40  ? 235 LYS   A CD  1 
ATOM   1217 C CE  . LYS   A 1 246 ? 136.868 149.836 190.207 1.00 63.38  ? 235 LYS   A CE  1 
ATOM   1218 N NZ  . LYS   A 1 246 ? 135.825 148.934 190.767 1.00 71.24  ? 235 LYS   A NZ  1 
ATOM   1219 N N   . ILE   A 1 247 ? 141.126 154.069 189.303 1.00 50.55  ? 236 ILE   A N   1 
ATOM   1220 C CA  . ILE   A 1 247 ? 141.268 155.388 188.693 1.00 48.31  ? 236 ILE   A CA  1 
ATOM   1221 C C   . ILE   A 1 247 ? 142.613 155.509 187.988 1.00 44.00  ? 236 ILE   A C   1 
ATOM   1222 O O   . ILE   A 1 247 ? 142.698 156.035 186.871 1.00 39.16  ? 236 ILE   A O   1 
ATOM   1223 C CB  . ILE   A 1 247 ? 141.076 156.494 189.747 1.00 53.69  ? 236 ILE   A CB  1 
ATOM   1224 C CG1 . ILE   A 1 247 ? 139.657 156.452 190.320 1.00 59.35  ? 236 ILE   A CG1 1 
ATOM   1225 C CG2 . ILE   A 1 247 ? 141.369 157.862 189.148 1.00 50.90  ? 236 ILE   A CG2 1 
ATOM   1226 C CD1 . ILE   A 1 247 ? 138.574 156.304 189.273 1.00 57.09  ? 236 ILE   A CD1 1 
ATOM   1227 N N   . CYS   A 1 248 ? 143.684 155.026 188.623 1.00 47.89  ? 237 CYS   A N   1 
ATOM   1228 C CA  . CYS   A 1 248 ? 144.996 155.053 187.990 1.00 39.94  ? 237 CYS   A CA  1 
ATOM   1229 C C   . CYS   A 1 248 ? 145.028 154.240 186.707 1.00 35.57  ? 237 CYS   A C   1 
ATOM   1230 O O   . CYS   A 1 248 ? 145.596 154.703 185.714 1.00 33.98  ? 237 CYS   A O   1 
ATOM   1231 C CB  . CYS   A 1 248 ? 146.065 154.539 188.956 1.00 50.50  ? 237 CYS   A CB  1 
ATOM   1232 S SG  . CYS   A 1 248 ? 146.642 155.766 190.150 1.00 84.05  ? 237 CYS   A SG  1 
ATOM   1233 N N   . VAL   A 1 249 ? 144.427 153.052 186.695 1.00 37.55  ? 238 VAL   A N   1 
ATOM   1234 C CA  . VAL   A 1 249 ? 144.368 152.266 185.465 1.00 32.44  ? 238 VAL   A CA  1 
ATOM   1235 C C   . VAL   A 1 249 ? 143.600 153.018 184.386 1.00 33.60  ? 238 VAL   A C   1 
ATOM   1236 O O   . VAL   A 1 249 ? 144.088 153.194 183.264 1.00 36.04  ? 238 VAL   A O   1 
ATOM   1237 C CB  . VAL   A 1 249 ? 143.750 150.881 185.731 1.00 32.42  ? 238 VAL   A CB  1 
ATOM   1238 C CG1 . VAL   A 1 249 ? 143.625 150.106 184.432 1.00 30.38  ? 238 VAL   A CG1 1 
ATOM   1239 C CG2 . VAL   A 1 249 ? 144.597 150.104 186.720 1.00 42.89  ? 238 VAL   A CG2 1 
ATOM   1240 N N   . PHE   A 1 250 ? 142.404 153.510 184.723 1.00 32.60  ? 239 PHE   A N   1 
ATOM   1241 C CA  . PHE   A 1 250 ? 141.564 154.166 183.725 1.00 29.48  ? 239 PHE   A CA  1 
ATOM   1242 C C   . PHE   A 1 250 ? 142.212 155.432 183.178 1.00 25.54  ? 239 PHE   A C   1 
ATOM   1243 O O   . PHE   A 1 250 ? 141.975 155.794 182.020 1.00 23.56  ? 239 PHE   A O   1 
ATOM   1244 C CB  . PHE   A 1 250 ? 140.188 154.472 184.327 1.00 33.03  ? 239 PHE   A CB  1 
ATOM   1245 C CG  . PHE   A 1 250 ? 139.281 155.273 183.427 1.00 31.51  ? 239 PHE   A CG  1 
ATOM   1246 C CD1 . PHE   A 1 250 ? 139.352 156.658 183.387 1.00 29.96  ? 239 PHE   A CD1 1 
ATOM   1247 C CD2 . PHE   A 1 250 ? 138.351 154.636 182.622 1.00 36.98  ? 239 PHE   A CD2 1 
ATOM   1248 C CE1 . PHE   A 1 250 ? 138.518 157.387 182.562 1.00 33.93  ? 239 PHE   A CE1 1 
ATOM   1249 C CE2 . PHE   A 1 250 ? 137.514 155.360 181.795 1.00 41.37  ? 239 PHE   A CE2 1 
ATOM   1250 C CZ  . PHE   A 1 250 ? 137.598 156.736 181.765 1.00 39.82  ? 239 PHE   A CZ  1 
ATOM   1251 N N   . ILE   A 1 251 ? 143.028 156.114 183.978 1.00 25.64  ? 240 ILE   A N   1 
ATOM   1252 C CA  . ILE   A 1 251 ? 143.613 157.378 183.545 1.00 22.48  ? 240 ILE   A CA  1 
ATOM   1253 C C   . ILE   A 1 251 ? 144.922 157.130 182.805 1.00 19.90  ? 240 ILE   A C   1 
ATOM   1254 O O   . ILE   A 1 251 ? 145.070 157.520 181.643 1.00 22.55  ? 240 ILE   A O   1 
ATOM   1255 C CB  . ILE   A 1 251 ? 143.822 158.331 184.737 1.00 27.35  ? 240 ILE   A CB  1 
ATOM   1256 C CG1 . ILE   A 1 251 ? 142.511 159.035 185.088 1.00 28.29  ? 240 ILE   A CG1 1 
ATOM   1257 C CG2 . ILE   A 1 251 ? 144.895 159.364 184.423 1.00 21.35  ? 240 ILE   A CG2 1 
ATOM   1258 C CD1 . ILE   A 1 251 ? 142.127 160.133 184.119 1.00 26.77  ? 240 ILE   A CD1 1 
ATOM   1259 N N   . PHE   A 1 252 ? 145.880 156.482 183.466 1.00 19.14  ? 241 PHE   A N   1 
ATOM   1260 C CA  . PHE   A 1 252 ? 147.216 156.324 182.913 1.00 19.49  ? 241 PHE   A CA  1 
ATOM   1261 C C   . PHE   A 1 252 ? 147.339 155.151 181.953 1.00 22.73  ? 241 PHE   A C   1 
ATOM   1262 O O   . PHE   A 1 252 ? 148.412 154.972 181.369 1.00 26.42  ? 241 PHE   A O   1 
ATOM   1263 C CB  . PHE   A 1 252 ? 148.232 156.156 184.045 1.00 24.03  ? 241 PHE   A CB  1 
ATOM   1264 C CG  . PHE   A 1 252 ? 149.111 157.354 184.257 1.00 24.57  ? 241 PHE   A CG  1 
ATOM   1265 C CD1 . PHE   A 1 252 ? 150.125 157.652 183.362 1.00 26.87  ? 241 PHE   A CD1 1 
ATOM   1266 C CD2 . PHE   A 1 252 ? 148.930 158.177 185.355 1.00 27.27  ? 241 PHE   A CD2 1 
ATOM   1267 C CE1 . PHE   A 1 252 ? 150.939 158.751 183.557 1.00 35.44  ? 241 PHE   A CE1 1 
ATOM   1268 C CE2 . PHE   A 1 252 ? 149.741 159.277 185.555 1.00 27.73  ? 241 PHE   A CE2 1 
ATOM   1269 C CZ  . PHE   A 1 252 ? 150.747 159.565 184.654 1.00 31.82  ? 241 PHE   A CZ  1 
ATOM   1270 N N   . ALA   A 1 253 ? 146.291 154.347 181.767 1.00 22.64  ? 242 ALA   A N   1 
ATOM   1271 C CA  . ALA   A 1 253 ? 146.393 153.167 180.925 1.00 20.90  ? 242 ALA   A CA  1 
ATOM   1272 C C   . ALA   A 1 253 ? 145.323 153.063 179.852 1.00 18.03  ? 242 ALA   A C   1 
ATOM   1273 O O   . ALA   A 1 253 ? 145.427 152.177 179.002 1.00 21.02  ? 242 ALA   A O   1 
ATOM   1274 C CB  . ALA   A 1 253 ? 146.352 151.891 181.779 1.00 28.24  ? 242 ALA   A CB  1 
ATOM   1275 N N   . PHE   A 1 254 ? 144.289 153.898 179.873 1.00 18.04  ? 243 PHE   A N   1 
ATOM   1276 C CA  . PHE   A 1 254 ? 143.326 153.915 178.779 1.00 16.89  ? 243 PHE   A CA  1 
ATOM   1277 C C   . PHE   A 1 254 ? 143.252 155.277 178.103 1.00 15.97  ? 243 PHE   A C   1 
ATOM   1278 O O   . PHE   A 1 254 ? 143.517 155.382 176.899 1.00 15.63  ? 243 PHE   A O   1 
ATOM   1279 C CB  . PHE   A 1 254 ? 141.952 153.490 179.310 1.00 23.76  ? 243 PHE   A CB  1 
ATOM   1280 C CG  . PHE   A 1 254 ? 140.890 153.404 178.257 1.00 27.50  ? 243 PHE   A CG  1 
ATOM   1281 C CD1 . PHE   A 1 254 ? 141.193 152.968 176.979 1.00 31.69  ? 243 PHE   A CD1 1 
ATOM   1282 C CD2 . PHE   A 1 254 ? 139.584 153.753 178.547 1.00 30.48  ? 243 PHE   A CD2 1 
ATOM   1283 C CE1 . PHE   A 1 254 ? 140.212 152.887 176.012 1.00 37.26  ? 243 PHE   A CE1 1 
ATOM   1284 C CE2 . PHE   A 1 254 ? 138.600 153.675 177.584 1.00 35.83  ? 243 PHE   A CE2 1 
ATOM   1285 C CZ  . PHE   A 1 254 ? 138.915 153.243 176.315 1.00 38.75  ? 243 PHE   A CZ  1 
ATOM   1286 N N   . ILE   A 1 255 ? 142.955 156.336 178.860 1.00 17.20  ? 244 ILE   A N   1 
ATOM   1287 C CA  . ILE   A 1 255 ? 142.645 157.625 178.254 1.00 15.65  ? 244 ILE   A CA  1 
ATOM   1288 C C   . ILE   A 1 255 ? 143.891 158.259 177.653 1.00 15.26  ? 244 ILE   A C   1 
ATOM   1289 O O   . ILE   A 1 255 ? 143.869 158.730 176.511 1.00 15.94  ? 244 ILE   A O   1 
ATOM   1290 C CB  . ILE   A 1 255 ? 141.979 158.549 179.287 1.00 17.55  ? 244 ILE   A CB  1 
ATOM   1291 C CG1 . ILE   A 1 255 ? 140.585 158.026 179.634 1.00 20.37  ? 244 ILE   A CG1 1 
ATOM   1292 C CG2 . ILE   A 1 255 ? 141.898 159.969 178.760 1.00 18.61  ? 244 ILE   A CG2 1 
ATOM   1293 C CD1 . ILE   A 1 255 ? 139.694 157.827 178.428 1.00 17.07  ? 244 ILE   A CD1 1 
ATOM   1294 N N   . MET   A 1 256 ? 144.991 158.292 178.403 1.00 13.64  ? 245 MET   A N   1 
ATOM   1295 C CA  . MET   A 1 256 ? 146.215 158.894 177.878 1.00 13.20  ? 245 MET   A CA  1 
ATOM   1296 C C   . MET   A 1 256 ? 146.764 158.152 176.665 1.00 14.50  ? 245 MET   A C   1 
ATOM   1297 O O   . MET   A 1 256 ? 147.078 158.812 175.658 1.00 18.94  ? 245 MET   A O   1 
ATOM   1298 C CB  . MET   A 1 256 ? 147.258 159.007 178.996 1.00 11.05  ? 245 MET   A CB  1 
ATOM   1299 N N   . PRO   A 1 257 ? 146.927 156.821 176.681 1.00 10.96  ? 246 PRO   A N   1 
ATOM   1300 C CA  . PRO   A 1 257 ? 147.387 156.145 175.455 1.00 11.66  ? 246 PRO   A CA  1 
ATOM   1301 C C   . PRO   A 1 257 ? 146.420 156.265 174.289 1.00 11.12  ? 246 PRO   A C   1 
ATOM   1302 O O   . PRO   A 1 257 ? 146.867 156.414 173.144 1.00 12.81  ? 246 PRO   A O   1 
ATOM   1303 C CB  . PRO   A 1 257 ? 147.563 154.689 175.904 1.00 14.94  ? 246 PRO   A CB  1 
ATOM   1304 C CG  . PRO   A 1 257 ? 146.756 154.565 177.131 1.00 16.62  ? 246 PRO   A CG  1 
ATOM   1305 C CD  . PRO   A 1 257 ? 146.829 155.879 177.807 1.00 12.68  ? 246 PRO   A CD  1 
ATOM   1306 N N   . VAL   A 1 258 ? 145.107 156.214 174.537 1.00 10.24  ? 247 VAL   A N   1 
ATOM   1307 C CA  . VAL   A 1 258 ? 144.155 156.379 173.441 1.00 11.02  ? 247 VAL   A CA  1 
ATOM   1308 C C   . VAL   A 1 258 ? 144.278 157.772 172.834 1.00 12.80  ? 247 VAL   A C   1 
ATOM   1309 O O   . VAL   A 1 258 ? 144.271 157.936 171.607 1.00 13.89  ? 247 VAL   A O   1 
ATOM   1310 C CB  . VAL   A 1 258 ? 142.723 156.090 173.924 1.00 10.10  ? 247 VAL   A CB  1 
ATOM   1311 C CG1 . VAL   A 1 258 ? 141.707 156.728 172.995 1.00 8.97   ? 247 VAL   A CG1 1 
ATOM   1312 C CG2 . VAL   A 1 258 ? 142.495 154.597 173.992 1.00 13.06  ? 247 VAL   A CG2 1 
ATOM   1313 N N   . LEU   A 1 259 ? 144.404 158.796 173.681 1.00 13.09  ? 248 LEU   A N   1 
ATOM   1314 C CA  . LEU   A 1 259 ? 144.576 160.154 173.185 1.00 14.10  ? 248 LEU   A CA  1 
ATOM   1315 C C   . LEU   A 1 259 ? 145.873 160.309 172.405 1.00 13.41  ? 248 LEU   A C   1 
ATOM   1316 O O   . LEU   A 1 259 ? 145.891 160.990 171.377 1.00 16.13  ? 248 LEU   A O   1 
ATOM   1317 C CB  . LEU   A 1 259 ? 144.534 161.147 174.346 1.00 12.35  ? 248 LEU   A CB  1 
ATOM   1318 C CG  . LEU   A 1 259 ? 143.282 162.019 174.436 1.00 13.87  ? 248 LEU   A CG  1 
ATOM   1319 C CD1 . LEU   A 1 259 ? 142.029 161.160 174.378 1.00 14.38  ? 248 LEU   A CD1 1 
ATOM   1320 C CD2 . LEU   A 1 259 ? 143.304 162.857 175.703 1.00 14.38  ? 248 LEU   A CD2 1 
ATOM   1321 N N   . ILE   A 1 260 ? 146.962 159.697 172.874 1.00 10.61  ? 249 ILE   A N   1 
ATOM   1322 C CA  . ILE   A 1 260 ? 148.227 159.798 172.151 1.00 9.74   ? 249 ILE   A CA  1 
ATOM   1323 C C   . ILE   A 1 260 ? 148.116 159.138 170.781 1.00 12.30  ? 249 ILE   A C   1 
ATOM   1324 O O   . ILE   A 1 260 ? 148.583 159.683 169.771 1.00 15.93  ? 249 ILE   A O   1 
ATOM   1325 C CB  . ILE   A 1 260 ? 149.368 159.190 172.983 1.00 9.16   ? 249 ILE   A CB  1 
ATOM   1326 C CG1 . ILE   A 1 260 ? 149.745 160.127 174.129 1.00 12.03  ? 249 ILE   A CG1 1 
ATOM   1327 C CG2 . ILE   A 1 260 ? 150.578 158.923 172.109 1.00 10.70  ? 249 ILE   A CG2 1 
ATOM   1328 C CD1 . ILE   A 1 260 ? 150.901 159.628 174.965 1.00 13.74  ? 249 ILE   A CD1 1 
ATOM   1329 N N   . ILE   A 1 261 ? 147.493 157.958 170.722 1.00 12.94  ? 250 ILE   A N   1 
ATOM   1330 C CA  . ILE   A 1 261 ? 147.319 157.268 169.446 1.00 13.35  ? 250 ILE   A CA  1 
ATOM   1331 C C   . ILE   A 1 261 ? 146.478 158.114 168.497 1.00 14.63  ? 250 ILE   A C   1 
ATOM   1332 O O   . ILE   A 1 261 ? 146.808 158.270 167.315 1.00 18.52  ? 250 ILE   A O   1 
ATOM   1333 C CB  . ILE   A 1 261 ? 146.692 155.880 169.669 1.00 13.32  ? 250 ILE   A CB  1 
ATOM   1334 C CG1 . ILE   A 1 261 ? 147.672 154.957 170.396 1.00 14.36  ? 250 ILE   A CG1 1 
ATOM   1335 C CG2 . ILE   A 1 261 ? 146.264 155.269 168.346 1.00 11.62  ? 250 ILE   A CG2 1 
ATOM   1336 C CD1 . ILE   A 1 261 ? 147.016 153.768 171.062 1.00 10.65  ? 250 ILE   A CD1 1 
ATOM   1337 N N   . THR   A 1 262 ? 145.376 158.675 169.004 1.00 13.53  ? 251 THR   A N   1 
ATOM   1338 C CA  . THR   A 1 262 ? 144.511 159.497 168.164 1.00 14.67  ? 251 THR   A CA  1 
ATOM   1339 C C   . THR   A 1 262 ? 145.242 160.736 167.664 1.00 14.44  ? 251 THR   A C   1 
ATOM   1340 O O   . THR   A 1 262 ? 145.123 161.104 166.491 1.00 16.36  ? 251 THR   A O   1 
ATOM   1341 C CB  . THR   A 1 262 ? 143.250 159.889 168.936 1.00 17.10  ? 251 THR   A CB  1 
ATOM   1342 O OG1 . THR   A 1 262 ? 142.304 158.814 168.884 1.00 19.33  ? 251 THR   A OG1 1 
ATOM   1343 C CG2 . THR   A 1 262 ? 142.615 161.139 168.341 1.00 13.78  ? 251 THR   A CG2 1 
ATOM   1344 N N   . VAL   A 1 263 ? 146.011 161.388 168.539 1.00 14.91  ? 252 VAL   A N   1 
ATOM   1345 C CA  . VAL   A 1 263 ? 146.753 162.584 168.150 1.00 14.24  ? 252 VAL   A CA  1 
ATOM   1346 C C   . VAL   A 1 263 ? 147.762 162.255 167.060 1.00 15.27  ? 252 VAL   A C   1 
ATOM   1347 O O   . VAL   A 1 263 ? 147.895 162.992 166.076 1.00 19.15  ? 252 VAL   A O   1 
ATOM   1348 C CB  . VAL   A 1 263 ? 147.430 163.212 169.383 1.00 11.90  ? 252 VAL   A CB  1 
ATOM   1349 C CG1 . VAL   A 1 263 ? 148.692 163.962 168.985 1.00 12.19  ? 252 VAL   A CG1 1 
ATOM   1350 C CG2 . VAL   A 1 263 ? 146.459 164.132 170.105 1.00 12.00  ? 252 VAL   A CG2 1 
ATOM   1351 N N   . CYS   A 1 264 ? 148.488 161.146 167.211 1.00 14.63  ? 253 CYS   A N   1 
ATOM   1352 C CA  . CYS   A 1 264 ? 149.465 160.770 166.194 1.00 17.62  ? 253 CYS   A CA  1 
ATOM   1353 C C   . CYS   A 1 264 ? 148.788 160.445 164.866 1.00 18.96  ? 253 CYS   A C   1 
ATOM   1354 O O   . CYS   A 1 264 ? 149.251 160.871 163.800 1.00 22.83  ? 253 CYS   A O   1 
ATOM   1355 C CB  . CYS   A 1 264 ? 150.299 159.585 166.678 1.00 21.22  ? 253 CYS   A CB  1 
ATOM   1356 S SG  . CYS   A 1 264 ? 151.520 160.004 167.936 1.00 36.13  ? 253 CYS   A SG  1 
ATOM   1357 N N   . TYR   A 1 265 ? 147.684 159.696 164.905 1.00 15.51  ? 254 TYR   A N   1 
ATOM   1358 C CA  . TYR   A 1 265 ? 147.087 159.243 163.654 1.00 15.16  ? 254 TYR   A CA  1 
ATOM   1359 C C   . TYR   A 1 265 ? 146.350 160.372 162.944 1.00 21.05  ? 254 TYR   A C   1 
ATOM   1360 O O   . TYR   A 1 265 ? 146.288 160.395 161.709 1.00 29.43  ? 254 TYR   A O   1 
ATOM   1361 C CB  . TYR   A 1 265 ? 146.164 158.054 163.907 1.00 12.38  ? 254 TYR   A CB  1 
ATOM   1362 C CG  . TYR   A 1 265 ? 146.834 156.734 163.607 1.00 14.37  ? 254 TYR   A CG  1 
ATOM   1363 C CD1 . TYR   A 1 265 ? 146.924 156.262 162.308 1.00 15.41  ? 254 TYR   A CD1 1 
ATOM   1364 C CD2 . TYR   A 1 265 ? 147.396 155.972 164.621 1.00 16.06  ? 254 TYR   A CD2 1 
ATOM   1365 C CE1 . TYR   A 1 265 ? 147.543 155.063 162.027 1.00 15.94  ? 254 TYR   A CE1 1 
ATOM   1366 C CE2 . TYR   A 1 265 ? 148.018 154.772 164.349 1.00 14.31  ? 254 TYR   A CE2 1 
ATOM   1367 C CZ  . TYR   A 1 265 ? 148.089 154.323 163.050 1.00 13.83  ? 254 TYR   A CZ  1 
ATOM   1368 O OH  . TYR   A 1 265 ? 148.707 153.127 162.772 1.00 14.06  ? 254 TYR   A OH  1 
ATOM   1369 N N   . GLY   A 1 266 ? 145.800 161.325 163.699 1.00 18.91  ? 255 GLY   A N   1 
ATOM   1370 C CA  . GLY   A 1 266 ? 145.145 162.462 163.081 1.00 16.20  ? 255 GLY   A CA  1 
ATOM   1371 C C   . GLY   A 1 266 ? 146.080 163.317 162.257 1.00 19.52  ? 255 GLY   A C   1 
ATOM   1372 O O   . GLY   A 1 266 ? 145.622 164.053 161.378 1.00 27.47  ? 255 GLY   A O   1 
ATOM   1373 N N   . LEU   A 1 267 ? 147.381 163.238 162.522 1.00 19.35  ? 256 LEU   A N   1 
ATOM   1374 C CA  . LEU   A 1 267 ? 148.381 163.901 161.700 1.00 23.47  ? 256 LEU   A CA  1 
ATOM   1375 C C   . LEU   A 1 267 ? 149.013 162.971 160.676 1.00 24.25  ? 256 LEU   A C   1 
ATOM   1376 O O   . LEU   A 1 267 ? 149.418 163.435 159.605 1.00 29.18  ? 256 LEU   A O   1 
ATOM   1377 C CB  . LEU   A 1 267 ? 149.475 164.510 162.583 1.00 20.34  ? 256 LEU   A CB  1 
ATOM   1378 C CG  . LEU   A 1 267 ? 148.983 165.143 163.886 1.00 19.35  ? 256 LEU   A CG  1 
ATOM   1379 C CD1 . LEU   A 1 267 ? 150.151 165.564 164.758 1.00 18.95  ? 256 LEU   A CD1 1 
ATOM   1380 C CD2 . LEU   A 1 267 ? 148.075 166.327 163.600 1.00 18.51  ? 256 LEU   A CD2 1 
ATOM   1381 N N   . MET   A 1 268 ? 149.089 161.670 160.971 1.00 24.23  ? 257 MET   A N   1 
ATOM   1382 C CA  . MET   A 1 268 ? 149.542 160.720 159.958 1.00 25.87  ? 257 MET   A CA  1 
ATOM   1383 C C   . MET   A 1 268 ? 148.614 160.720 158.753 1.00 24.94  ? 257 MET   A C   1 
ATOM   1384 O O   . MET   A 1 268 ? 149.072 160.639 157.608 1.00 30.75  ? 257 MET   A O   1 
ATOM   1385 C CB  . MET   A 1 268 ? 149.631 159.306 160.529 1.00 32.68  ? 257 MET   A CB  1 
ATOM   1386 C CG  . MET   A 1 268 ? 151.038 158.780 160.704 1.00 37.27  ? 257 MET   A CG  1 
ATOM   1387 S SD  . MET   A 1 268 ? 151.076 157.346 161.790 1.00 34.93  ? 257 MET   A SD  1 
ATOM   1388 C CE  . MET   A 1 268 ? 150.623 158.066 163.357 1.00 24.56  ? 257 MET   A CE  1 
ATOM   1389 N N   . ILE   A 1 269 ? 147.303 160.789 158.991 1.00 22.32  ? 258 ILE   A N   1 
ATOM   1390 C CA  . ILE   A 1 269 ? 146.346 160.776 157.888 1.00 27.05  ? 258 ILE   A CA  1 
ATOM   1391 C C   . ILE   A 1 269 ? 146.549 161.991 156.989 1.00 34.35  ? 258 ILE   A C   1 
ATOM   1392 O O   . ILE   A 1 269 ? 146.587 161.876 155.756 1.00 34.02  ? 258 ILE   A O   1 
ATOM   1393 C CB  . ILE   A 1 269 ? 144.908 160.706 158.433 1.00 22.24  ? 258 ILE   A CB  1 
ATOM   1394 C CG1 . ILE   A 1 269 ? 144.688 159.395 159.188 1.00 23.14  ? 258 ILE   A CG1 1 
ATOM   1395 C CG2 . ILE   A 1 269 ? 143.899 160.853 157.307 1.00 31.01  ? 258 ILE   A CG2 1 
ATOM   1396 C CD1 . ILE   A 1 269 ? 144.961 158.162 158.368 1.00 32.33  ? 258 ILE   A CD1 1 
ATOM   1397 N N   . LEU   A 1 270 ? 146.691 163.174 157.592 1.00 32.12  ? 259 LEU   A N   1 
ATOM   1398 C CA  . LEU   A 1 270 ? 146.899 164.386 156.807 1.00 31.80  ? 259 LEU   A CA  1 
ATOM   1399 C C   . LEU   A 1 270 ? 148.231 164.350 156.069 1.00 34.65  ? 259 LEU   A C   1 
ATOM   1400 O O   . LEU   A 1 270 ? 148.316 164.780 154.913 1.00 40.33  ? 259 LEU   A O   1 
ATOM   1401 C CB  . LEU   A 1 270 ? 146.812 165.615 157.709 1.00 28.48  ? 259 LEU   A CB  1 
ATOM   1402 C CG  . LEU   A 1 270 ? 145.584 165.670 158.619 1.00 26.86  ? 259 LEU   A CG  1 
ATOM   1403 C CD1 . LEU   A 1 270 ? 145.565 166.958 159.425 1.00 26.01  ? 259 LEU   A CD1 1 
ATOM   1404 C CD2 . LEU   A 1 270 ? 144.306 165.518 157.810 1.00 26.32  ? 259 LEU   A CD2 1 
ATOM   1405 N N   . ARG   A 1 271 ? 149.285 163.843 156.715 1.00 34.12  ? 260 ARG   A N   1 
ATOM   1406 C CA  . ARG   A 1 271 ? 150.570 163.724 156.038 1.00 32.86  ? 260 ARG   A CA  1 
ATOM   1407 C C   . ARG   A 1 271 ? 150.523 162.724 154.893 1.00 36.78  ? 260 ARG   A C   1 
ATOM   1408 O O   . ARG   A 1 271 ? 151.260 162.885 153.916 1.00 43.00  ? 260 ARG   A O   1 
ATOM   1409 C CB  . ARG   A 1 271 ? 151.658 163.319 157.030 1.00 35.76  ? 260 ARG   A CB  1 
ATOM   1410 N N   . LEU   A 1 272 ? 149.686 161.692 154.996 1.00 36.08  ? 261 LEU   A N   1 
ATOM   1411 C CA  . LEU   A 1 272 ? 149.517 160.767 153.882 1.00 37.37  ? 261 LEU   A CA  1 
ATOM   1412 C C   . LEU   A 1 272 ? 148.759 161.426 152.739 1.00 45.77  ? 261 LEU   A C   1 
ATOM   1413 O O   . LEU   A 1 272 ? 149.113 161.248 151.567 1.00 50.09  ? 261 LEU   A O   1 
ATOM   1414 C CB  . LEU   A 1 272 ? 148.784 159.510 154.346 1.00 31.11  ? 261 LEU   A CB  1 
ATOM   1415 C CG  . LEU   A 1 272 ? 149.610 158.241 154.551 1.00 30.79  ? 261 LEU   A CG  1 
ATOM   1416 C CD1 . LEU   A 1 272 ? 150.772 158.515 155.479 1.00 37.91  ? 261 LEU   A CD1 1 
ATOM   1417 C CD2 . LEU   A 1 272 ? 148.745 157.127 155.098 1.00 35.12  ? 261 LEU   A CD2 1 
ATOM   1418 N N   . LYS   A 1 273 ? 147.714 162.191 153.061 1.00 44.35  ? 262 LYS   A N   1 
ATOM   1419 C CA  . LYS   A 1 273 ? 146.872 162.788 152.029 1.00 48.77  ? 262 LYS   A CA  1 
ATOM   1420 C C   . LYS   A 1 273 ? 147.601 163.885 151.259 1.00 47.80  ? 262 LYS   A C   1 
ATOM   1421 O O   . LYS   A 1 273 ? 147.519 163.948 150.028 1.00 49.92  ? 262 LYS   A O   1 
ATOM   1422 C CB  . LYS   A 1 273 ? 145.590 163.339 152.656 1.00 44.09  ? 262 LYS   A CB  1 
ATOM   1423 N N   . SER   A 1 274 ? 148.322 164.757 151.967 1.00 49.21  ? 263 SER   A N   1 
ATOM   1424 C CA  . SER   A 1 274 ? 148.879 165.947 151.333 1.00 51.65  ? 263 SER   A CA  1 
ATOM   1425 C C   . SER   A 1 274 ? 150.234 165.696 150.682 1.00 54.34  ? 263 SER   A C   1 
ATOM   1426 O O   . SER   A 1 274 ? 150.765 166.598 150.025 1.00 57.56  ? 263 SER   A O   1 
ATOM   1427 C CB  . SER   A 1 274 ? 149.000 167.075 152.359 1.00 46.74  ? 263 SER   A CB  1 
ATOM   1428 N N   . VAL   A 1 275 ? 150.808 164.508 150.845 1.00 53.11  ? 264 VAL   A N   1 
ATOM   1429 C CA  . VAL   A 1 275 ? 152.133 164.195 150.318 1.00 57.80  ? 264 VAL   A CA  1 
ATOM   1430 C C   . VAL   A 1 275 ? 151.988 163.112 149.258 1.00 62.39  ? 264 VAL   A C   1 
ATOM   1431 O O   . VAL   A 1 275 ? 151.342 162.083 149.493 1.00 59.82  ? 264 VAL   A O   1 
ATOM   1432 C CB  . VAL   A 1 275 ? 153.099 163.759 151.429 1.00 62.88  ? 264 VAL   A CB  1 
ATOM   1433 C CG1 . VAL   A 1 275 ? 154.431 163.337 150.838 1.00 61.34  ? 264 VAL   A CG1 1 
ATOM   1434 C CG2 . VAL   A 1 275 ? 153.296 164.889 152.427 1.00 69.58  ? 264 VAL   A CG2 1 
ATOM   1435 N N   . ARG   A 1 276 ? 152.585 163.354 148.088 1.00 67.20  ? 265 ARG   A N   1 
ATOM   1436 C CA  . ARG   A 1 276 ? 152.557 162.372 147.007 1.00 64.14  ? 265 ARG   A CA  1 
ATOM   1437 C C   . ARG   A 1 276 ? 153.289 161.094 147.399 1.00 67.73  ? 265 ARG   A C   1 
ATOM   1438 O O   . ARG   A 1 276 ? 152.693 160.012 147.445 1.00 66.60  ? 265 ARG   A O   1 
ATOM   1439 C CB  . ARG   A 1 276 ? 153.171 162.979 145.745 1.00 63.28  ? 265 ARG   A CB  1 
ATOM   1440 C CG  . ARG   A 1 276 ? 153.195 162.053 144.539 1.00 69.33  ? 265 ARG   A CG  1 
ATOM   1441 C CD  . ARG   A 1 276 ? 153.404 162.836 143.250 1.00 72.40  ? 265 ARG   A CD  1 
ATOM   1442 N NE  . ARG   A 1 276 ? 153.715 161.972 142.117 1.00 76.68  ? 265 ARG   A NE  1 
ATOM   1443 C CZ  . ARG   A 1 276 ? 152.826 161.244 141.454 1.00 82.30  ? 265 ARG   A CZ  1 
ATOM   1444 N NH1 . ARG   A 1 276 ? 151.548 161.234 141.794 1.00 79.64  ? 265 ARG   A NH1 1 
ATOM   1445 N NH2 . ARG   A 1 276 ? 153.230 160.508 140.423 1.00 82.31  ? 265 ARG   A NH2 1 
ATOM   1446 N N   . LEU   A 1 277 ? 154.584 161.201 147.688 1.00 69.12  ? 266 LEU   A N   1 
ATOM   1447 C CA  . LEU   A 1 277 ? 155.411 160.044 148.005 1.00 67.53  ? 266 LEU   A CA  1 
ATOM   1448 C C   . LEU   A 1 277 ? 156.068 160.251 149.359 1.00 70.05  ? 266 LEU   A C   1 
ATOM   1449 O O   . LEU   A 1 277 ? 156.672 161.299 149.604 1.00 73.04  ? 266 LEU   A O   1 
ATOM   1450 C CB  . LEU   A 1 277 ? 156.477 159.821 146.927 1.00 65.28  ? 266 LEU   A CB  1 
ATOM   1451 C CG  . LEU   A 1 277 ? 155.958 159.415 145.549 1.00 66.32  ? 266 LEU   A CG  1 
ATOM   1452 C CD1 . LEU   A 1 277 ? 157.075 158.834 144.704 1.00 68.47  ? 266 LEU   A CD1 1 
ATOM   1453 C CD2 . LEU   A 1 277 ? 154.831 158.410 145.696 1.00 60.01  ? 266 LEU   A CD2 1 
ATOM   1454 N N   . LEU   A 1 278 ? 155.952 159.250 150.232 1.00 67.81  ? 267 LEU   A N   1 
ATOM   1455 C CA  . LEU   A 1 278 ? 156.541 159.351 151.563 1.00 72.08  ? 267 LEU   A CA  1 
ATOM   1456 C C   . LEU   A 1 278 ? 158.020 158.980 151.545 1.00 75.99  ? 267 LEU   A C   1 
ATOM   1457 O O   . LEU   A 1 278 ? 158.884 159.805 151.864 1.00 79.15  ? 267 LEU   A O   1 
ATOM   1458 C CB  . LEU   A 1 278 ? 155.776 158.455 152.539 1.00 69.73  ? 267 LEU   A CB  1 
ATOM   1459 C CG  . LEU   A 1 278 ? 154.374 158.913 152.937 1.00 66.36  ? 267 LEU   A CG  1 
ATOM   1460 C CD1 . LEU   A 1 278 ? 153.613 157.754 153.543 1.00 54.86  ? 267 LEU   A CD1 1 
ATOM   1461 C CD2 . LEU   A 1 278 ? 154.438 160.079 153.907 1.00 63.07  ? 267 LEU   A CD2 1 
ATOM   1462 N N   . SER   A 1 279 ? 158.327 157.740 151.173 1.00 76.99  ? 268 SER   A N   1 
ATOM   1463 C CA  . SER   A 1 279 ? 159.692 157.234 151.167 1.00 79.30  ? 268 SER   A CA  1 
ATOM   1464 C C   . SER   A 1 279 ? 160.351 157.320 149.797 1.00 72.68  ? 268 SER   A C   1 
ATOM   1465 O O   . SER   A 1 279 ? 161.476 156.837 149.633 1.00 74.27  ? 268 SER   A O   1 
ATOM   1466 C CB  . SER   A 1 279 ? 159.719 155.786 151.664 1.00 72.26  ? 268 SER   A CB  1 
ATOM   1467 N N   . GLY   A 1 280 ? 159.682 157.915 148.813 1.00 68.00  ? 269 GLY   A N   1 
ATOM   1468 C CA  . GLY   A 1 280 ? 160.231 157.997 147.476 1.00 71.80  ? 269 GLY   A CA  1 
ATOM   1469 C C   . GLY   A 1 280 ? 159.986 156.739 146.669 1.00 69.77  ? 269 GLY   A C   1 
ATOM   1470 O O   . GLY   A 1 280 ? 159.335 156.783 145.621 1.00 69.25  ? 269 GLY   A O   1 
ATOM   1471 N N   . SER   A 1 281 ? 160.510 155.611 147.143 1.00 65.78  ? 270 SER   A N   1 
ATOM   1472 C CA  . SER   A 1 281 ? 160.264 154.340 146.476 1.00 65.16  ? 270 SER   A CA  1 
ATOM   1473 C C   . SER   A 1 281 ? 158.792 153.967 146.590 1.00 65.61  ? 270 SER   A C   1 
ATOM   1474 O O   . SER   A 1 281 ? 158.205 154.029 147.674 1.00 66.39  ? 270 SER   A O   1 
ATOM   1475 C CB  . SER   A 1 281 ? 161.140 153.246 147.084 1.00 65.82  ? 270 SER   A CB  1 
ATOM   1476 N N   . ARG   A 1 282 ? 158.192 153.585 145.460 1.00 65.47  ? 271 ARG   A N   1 
ATOM   1477 C CA  . ARG   A 1 282 ? 156.782 153.211 145.468 1.00 64.52  ? 271 ARG   A CA  1 
ATOM   1478 C C   . ARG   A 1 282 ? 156.546 151.963 146.308 1.00 62.50  ? 271 ARG   A C   1 
ATOM   1479 O O   . ARG   A 1 282 ? 155.566 151.886 147.057 1.00 64.43  ? 271 ARG   A O   1 
ATOM   1480 C CB  . ARG   A 1 282 ? 156.284 153.004 144.037 1.00 65.63  ? 271 ARG   A CB  1 
ATOM   1481 C CG  . ARG   A 1 282 ? 156.183 154.289 143.231 1.00 66.79  ? 271 ARG   A CG  1 
ATOM   1482 C CD  . ARG   A 1 282 ? 155.571 154.045 141.861 1.00 70.48  ? 271 ARG   A CD  1 
ATOM   1483 N NE  . ARG   A 1 282 ? 155.557 155.255 141.047 1.00 67.76  ? 271 ARG   A NE  1 
ATOM   1484 C CZ  . ARG   A 1 282 ? 154.774 155.441 139.993 1.00 63.46  ? 271 ARG   A CZ  1 
ATOM   1485 N NH1 . ARG   A 1 282 ? 153.920 154.514 139.594 1.00 64.11  ? 271 ARG   A NH1 1 
ATOM   1486 N NH2 . ARG   A 1 282 ? 154.848 156.589 139.326 1.00 59.60  ? 271 ARG   A NH2 1 
ATOM   1487 N N   . GLU   A 1 283 ? 157.435 150.972 146.197 1.00 60.85  ? 272 GLU   A N   1 
ATOM   1488 C CA  . GLU   A 1 283 ? 157.296 149.763 147.002 1.00 59.24  ? 272 GLU   A CA  1 
ATOM   1489 C C   . GLU   A 1 283 ? 157.453 150.068 148.487 1.00 60.66  ? 272 GLU   A C   1 
ATOM   1490 O O   . GLU   A 1 283 ? 156.694 149.556 149.318 1.00 58.71  ? 272 GLU   A O   1 
ATOM   1491 C CB  . GLU   A 1 283 ? 158.316 148.715 146.558 1.00 56.77  ? 272 GLU   A CB  1 
ATOM   1492 N N   . LYS   A 1 284 ? 158.435 150.902 148.839 1.00 60.02  ? 273 LYS   A N   1 
ATOM   1493 C CA  . LYS   A 1 284 ? 158.632 151.262 150.240 1.00 56.57  ? 273 LYS   A CA  1 
ATOM   1494 C C   . LYS   A 1 284 ? 157.442 152.044 150.780 1.00 55.64  ? 273 LYS   A C   1 
ATOM   1495 O O   . LYS   A 1 284 ? 157.004 151.818 151.914 1.00 55.52  ? 273 LYS   A O   1 
ATOM   1496 C CB  . LYS   A 1 284 ? 159.921 152.067 150.399 1.00 59.08  ? 273 LYS   A CB  1 
ATOM   1497 N N   . ASP   A 1 285 ? 156.908 152.972 149.983 1.00 57.95  ? 274 ASP   A N   1 
ATOM   1498 C CA  . ASP   A 1 285 ? 155.737 153.732 150.408 1.00 57.55  ? 274 ASP   A CA  1 
ATOM   1499 C C   . ASP   A 1 285 ? 154.530 152.821 150.597 1.00 52.74  ? 274 ASP   A C   1 
ATOM   1500 O O   . ASP   A 1 285 ? 153.770 152.975 151.561 1.00 48.98  ? 274 ASP   A O   1 
ATOM   1501 C CB  . ASP   A 1 285 ? 155.442 154.835 149.390 1.00 55.45  ? 274 ASP   A CB  1 
ATOM   1502 C CG  . ASP   A 1 285 ? 154.173 155.603 149.703 1.00 54.23  ? 274 ASP   A CG  1 
ATOM   1503 O OD1 . ASP   A 1 285 ? 153.070 155.064 149.477 1.00 53.19  ? 274 ASP   A OD1 1 
ATOM   1504 O OD2 . ASP   A 1 285 ? 154.279 156.754 150.178 1.00 51.87  ? 274 ASP   A OD2 1 
ATOM   1505 N N   . ARG   A 1 286 ? 154.337 151.868 149.681 1.00 53.63  ? 275 ARG   A N   1 
ATOM   1506 C CA  . ARG   A 1 286 ? 153.236 150.921 149.815 1.00 48.96  ? 275 ARG   A CA  1 
ATOM   1507 C C   . ARG   A 1 286 ? 153.391 150.069 151.067 1.00 46.41  ? 275 ARG   A C   1 
ATOM   1508 O O   . ARG   A 1 286 ? 152.414 149.823 151.783 1.00 44.36  ? 275 ARG   A O   1 
ATOM   1509 C CB  . ARG   A 1 286 ? 153.155 150.033 148.574 1.00 51.48  ? 275 ARG   A CB  1 
ATOM   1510 N N   . ASN   A 1 287 ? 154.611 149.603 151.343 1.00 47.28  ? 276 ASN   A N   1 
ATOM   1511 C CA  . ASN   A 1 287 ? 154.847 148.816 152.549 1.00 46.76  ? 276 ASN   A CA  1 
ATOM   1512 C C   . ASN   A 1 287 ? 154.577 149.638 153.802 1.00 43.00  ? 276 ASN   A C   1 
ATOM   1513 O O   . ASN   A 1 287 ? 153.974 149.141 154.761 1.00 39.73  ? 276 ASN   A O   1 
ATOM   1514 C CB  . ASN   A 1 287 ? 156.279 148.281 152.554 1.00 53.42  ? 276 ASN   A CB  1 
ATOM   1515 C CG  . ASN   A 1 287 ? 156.556 147.371 153.735 1.00 58.75  ? 276 ASN   A CG  1 
ATOM   1516 O OD1 . ASN   A 1 287 ? 155.648 146.739 154.274 1.00 58.02  ? 276 ASN   A OD1 1 
ATOM   1517 N ND2 . ASN   A 1 287 ? 157.817 147.301 154.144 1.00 60.27  ? 276 ASN   A ND2 1 
ATOM   1518 N N   . LEU   A 1 288 ? 155.019 150.898 153.813 1.00 44.26  ? 277 LEU   A N   1 
ATOM   1519 C CA  . LEU   A 1 288 ? 154.775 151.765 154.961 1.00 38.79  ? 277 LEU   A CA  1 
ATOM   1520 C C   . LEU   A 1 288 ? 153.282 151.963 155.190 1.00 36.37  ? 277 LEU   A C   1 
ATOM   1521 O O   . LEU   A 1 288 ? 152.791 151.827 156.316 1.00 38.11  ? 277 LEU   A O   1 
ATOM   1522 C CB  . LEU   A 1 288 ? 155.472 153.111 154.754 1.00 34.78  ? 277 LEU   A CB  1 
ATOM   1523 C CG  . LEU   A 1 288 ? 155.118 154.245 155.718 1.00 35.51  ? 277 LEU   A CG  1 
ATOM   1524 C CD1 . LEU   A 1 288 ? 155.440 153.866 157.151 1.00 40.49  ? 277 LEU   A CD1 1 
ATOM   1525 C CD2 . LEU   A 1 288 ? 155.854 155.513 155.327 1.00 43.90  ? 277 LEU   A CD2 1 
ATOM   1526 N N   . ARG   A 1 289 ? 152.540 152.276 154.126 1.00 36.86  ? 278 ARG   A N   1 
ATOM   1527 C CA  . ARG   A 1 289 ? 151.103 152.475 154.263 1.00 34.85  ? 278 ARG   A CA  1 
ATOM   1528 C C   . ARG   A 1 289 ? 150.379 151.202 154.684 1.00 32.80  ? 278 ARG   A C   1 
ATOM   1529 O O   . ARG   A 1 289 ? 149.474 151.270 155.521 1.00 31.51  ? 278 ARG   A O   1 
ATOM   1530 C CB  . ARG   A 1 289 ? 150.522 153.014 152.956 1.00 35.99  ? 278 ARG   A CB  1 
ATOM   1531 C CG  . ARG   A 1 289 ? 151.054 154.389 152.592 1.00 38.57  ? 278 ARG   A CG  1 
ATOM   1532 C CD  . ARG   A 1 289 ? 150.426 154.931 151.322 1.00 38.82  ? 278 ARG   A CD  1 
ATOM   1533 N NE  . ARG   A 1 289 ? 151.241 155.987 150.734 1.00 42.22  ? 278 ARG   A NE  1 
ATOM   1534 C CZ  . ARG   A 1 289 ? 150.895 157.266 150.686 1.00 44.39  ? 278 ARG   A CZ  1 
ATOM   1535 N NH1 . ARG   A 1 289 ? 149.739 157.687 151.171 1.00 42.55  ? 278 ARG   A NH1 1 
ATOM   1536 N NH2 . ARG   A 1 289 ? 151.730 158.144 150.140 1.00 48.77  ? 278 ARG   A NH2 1 
ATOM   1537 N N   . ARG   A 1 290 ? 150.765 150.045 154.146 1.00 32.86  ? 279 ARG   A N   1 
ATOM   1538 C CA  . ARG   A 1 290 ? 150.149 148.782 154.536 1.00 30.00  ? 279 ARG   A CA  1 
ATOM   1539 C C   . ARG   A 1 290 ? 150.430 148.419 155.989 1.00 31.96  ? 279 ARG   A C   1 
ATOM   1540 O O   . ARG   A 1 290 ? 149.519 147.990 156.706 1.00 34.04  ? 279 ARG   A O   1 
ATOM   1541 C CB  . ARG   A 1 290 ? 150.633 147.657 153.618 1.00 31.79  ? 279 ARG   A CB  1 
ATOM   1542 N N   . ILE   A 1 291 ? 151.674 148.582 156.446 1.00 35.00  ? 280 ILE   A N   1 
ATOM   1543 C CA  . ILE   A 1 291 ? 151.989 148.254 157.832 1.00 28.92  ? 280 ILE   A CA  1 
ATOM   1544 C C   . ILE   A 1 291 ? 151.322 149.244 158.779 1.00 22.84  ? 280 ILE   A C   1 
ATOM   1545 O O   . ILE   A 1 291 ? 150.906 148.878 159.883 1.00 21.67  ? 280 ILE   A O   1 
ATOM   1546 C CB  . ILE   A 1 291 ? 153.514 148.177 158.042 1.00 32.67  ? 280 ILE   A CB  1 
ATOM   1547 C CG1 . ILE   A 1 291 ? 153.838 147.433 159.339 1.00 30.42  ? 280 ILE   A CG1 1 
ATOM   1548 C CG2 . ILE   A 1 291 ? 154.150 149.554 158.041 1.00 35.20  ? 280 ILE   A CG2 1 
ATOM   1549 C CD1 . ILE   A 1 291 ? 153.507 145.959 159.294 1.00 33.36  ? 280 ILE   A CD1 1 
ATOM   1550 N N   . THR   A 1 292 ? 151.183 150.506 158.359 1.00 23.72  ? 281 THR   A N   1 
ATOM   1551 C CA  . THR   A 1 292 ? 150.458 151.471 159.178 1.00 21.62  ? 281 THR   A CA  1 
ATOM   1552 C C   . THR   A 1 292 ? 148.977 151.124 159.249 1.00 22.07  ? 281 THR   A C   1 
ATOM   1553 O O   . THR   A 1 292 ? 148.347 151.270 160.302 1.00 26.33  ? 281 THR   A O   1 
ATOM   1554 C CB  . THR   A 1 292 ? 150.659 152.882 158.629 1.00 19.50  ? 281 THR   A CB  1 
ATOM   1555 O OG1 . THR   A 1 292 ? 152.058 153.187 158.608 1.00 26.01  ? 281 THR   A OG1 1 
ATOM   1556 C CG2 . THR   A 1 292 ? 149.945 153.897 159.498 1.00 19.41  ? 281 THR   A CG2 1 
ATOM   1557 N N   . ARG   A 1 293 ? 148.405 150.649 158.141 1.00 21.93  ? 282 ARG   A N   1 
ATOM   1558 C CA  . ARG   A 1 293 ? 147.021 150.189 158.170 1.00 19.57  ? 282 ARG   A CA  1 
ATOM   1559 C C   . ARG   A 1 293 ? 146.859 148.999 159.103 1.00 16.74  ? 282 ARG   A C   1 
ATOM   1560 O O   . ARG   A 1 293 ? 145.884 148.923 159.859 1.00 19.18  ? 282 ARG   A O   1 
ATOM   1561 C CB  . ARG   A 1 293 ? 146.554 149.824 156.762 1.00 27.04  ? 282 ARG   A CB  1 
ATOM   1562 C CG  . ARG   A 1 293 ? 145.071 149.512 156.672 1.00 26.49  ? 282 ARG   A CG  1 
ATOM   1563 C CD  . ARG   A 1 293 ? 144.756 148.704 155.426 1.00 30.06  ? 282 ARG   A CD  1 
ATOM   1564 N NE  . ARG   A 1 293 ? 145.338 147.370 155.490 1.00 27.51  ? 282 ARG   A NE  1 
ATOM   1565 C CZ  . ARG   A 1 293 ? 145.564 146.599 154.436 1.00 35.80  ? 282 ARG   A CZ  1 
ATOM   1566 N NH1 . ARG   A 1 293 ? 145.264 146.999 153.211 1.00 39.41  ? 282 ARG   A NH1 1 
ATOM   1567 N NH2 . ARG   A 1 293 ? 146.104 145.397 154.614 1.00 39.33  ? 282 ARG   A NH2 1 
ATOM   1568 N N   . MET   A 1 294 ? 147.802 148.056 159.063 1.00 17.75  ? 283 MET   A N   1 
ATOM   1569 C CA  . MET   A 1 294 ? 147.729 146.904 159.959 1.00 19.64  ? 283 MET   A CA  1 
ATOM   1570 C C   . MET   A 1 294 ? 147.840 147.330 161.419 1.00 19.98  ? 283 MET   A C   1 
ATOM   1571 O O   . MET   A 1 294 ? 147.112 146.819 162.278 1.00 18.57  ? 283 MET   A O   1 
ATOM   1572 C CB  . MET   A 1 294 ? 148.820 145.894 159.615 1.00 20.53  ? 283 MET   A CB  1 
ATOM   1573 C CG  . MET   A 1 294 ? 148.523 144.488 160.102 1.00 23.10  ? 283 MET   A CG  1 
ATOM   1574 S SD  . MET   A 1 294 ? 149.206 144.154 161.732 1.00 32.82  ? 283 MET   A SD  1 
ATOM   1575 C CE  . MET   A 1 294 ? 150.953 144.359 161.407 1.00 33.74  ? 283 MET   A CE  1 
ATOM   1576 N N   . VAL   A 1 295 ? 148.751 148.259 161.716 1.00 19.47  ? 284 VAL   A N   1 
ATOM   1577 C CA  . VAL   A 1 295 ? 148.902 148.758 163.080 1.00 12.66  ? 284 VAL   A CA  1 
ATOM   1578 C C   . VAL   A 1 295 ? 147.619 149.437 163.540 1.00 12.26  ? 284 VAL   A C   1 
ATOM   1579 O O   . VAL   A 1 295 ? 147.159 149.234 164.670 1.00 19.90  ? 284 VAL   A O   1 
ATOM   1580 C CB  . VAL   A 1 295 ? 150.109 149.708 163.168 1.00 13.10  ? 284 VAL   A CB  1 
ATOM   1581 C CG1 . VAL   A 1 295 ? 150.015 150.581 164.402 1.00 17.78  ? 284 VAL   A CG1 1 
ATOM   1582 C CG2 . VAL   A 1 295 ? 151.402 148.914 163.175 1.00 20.70  ? 284 VAL   A CG2 1 
ATOM   1583 N N   . LEU   A 1 296 ? 147.020 150.252 162.670 1.00 11.42  ? 285 LEU   A N   1 
ATOM   1584 C CA  . LEU   A 1 296 ? 145.779 150.928 163.027 1.00 12.02  ? 285 LEU   A CA  1 
ATOM   1585 C C   . LEU   A 1 296 ? 144.653 149.930 163.261 1.00 13.90  ? 285 LEU   A C   1 
ATOM   1586 O O   . LEU   A 1 296 ? 143.839 150.105 164.174 1.00 17.05  ? 285 LEU   A O   1 
ATOM   1587 C CB  . LEU   A 1 296 ? 145.394 151.927 161.938 1.00 12.91  ? 285 LEU   A CB  1 
ATOM   1588 C CG  . LEU   A 1 296 ? 144.078 152.675 162.151 1.00 9.49   ? 285 LEU   A CG  1 
ATOM   1589 C CD1 . LEU   A 1 296 ? 144.108 153.447 163.458 1.00 8.39   ? 285 LEU   A CD1 1 
ATOM   1590 C CD2 . LEU   A 1 296 ? 143.796 153.602 160.983 1.00 21.30  ? 285 LEU   A CD2 1 
ATOM   1591 N N   . VAL   A 1 297 ? 144.587 148.874 162.448 1.00 14.21  ? 286 VAL   A N   1 
ATOM   1592 C CA  . VAL   A 1 297 ? 143.535 147.879 162.628 1.00 13.97  ? 286 VAL   A CA  1 
ATOM   1593 C C   . VAL   A 1 297 ? 143.731 147.121 163.935 1.00 16.06  ? 286 VAL   A C   1 
ATOM   1594 O O   . VAL   A 1 297 ? 142.766 146.845 164.653 1.00 19.62  ? 286 VAL   A O   1 
ATOM   1595 C CB  . VAL   A 1 297 ? 143.471 146.924 161.424 1.00 13.64  ? 286 VAL   A CB  1 
ATOM   1596 C CG1 . VAL   A 1 297 ? 142.493 145.805 161.710 1.00 14.47  ? 286 VAL   A CG1 1 
ATOM   1597 C CG2 . VAL   A 1 297 ? 143.043 147.676 160.179 1.00 17.54  ? 286 VAL   A CG2 1 
ATOM   1598 N N   . VAL   A 1 298 ? 144.976 146.767 164.263 1.00 15.77  ? 287 VAL   A N   1 
ATOM   1599 C CA  . VAL   A 1 298 ? 145.244 146.092 165.532 1.00 13.92  ? 287 VAL   A CA  1 
ATOM   1600 C C   . VAL   A 1 298 ? 144.872 146.994 166.703 1.00 14.92  ? 287 VAL   A C   1 
ATOM   1601 O O   . VAL   A 1 298 ? 144.276 146.544 167.691 1.00 18.56  ? 287 VAL   A O   1 
ATOM   1602 C CB  . VAL   A 1 298 ? 146.716 145.650 165.604 1.00 14.14  ? 287 VAL   A CB  1 
ATOM   1603 C CG1 . VAL   A 1 298 ? 147.113 145.351 167.036 1.00 16.67  ? 287 VAL   A CG1 1 
ATOM   1604 C CG2 . VAL   A 1 298 ? 146.943 144.436 164.726 1.00 18.01  ? 287 VAL   A CG2 1 
ATOM   1605 N N   . VAL   A 1 299 ? 145.212 148.281 166.607 1.00 12.70  ? 288 VAL   A N   1 
ATOM   1606 C CA  . VAL   A 1 299 ? 144.882 149.229 167.667 1.00 10.85  ? 288 VAL   A CA  1 
ATOM   1607 C C   . VAL   A 1 299 ? 143.373 149.343 167.832 1.00 14.95  ? 288 VAL   A C   1 
ATOM   1608 O O   . VAL   A 1 299 ? 142.854 149.346 168.955 1.00 22.53  ? 288 VAL   A O   1 
ATOM   1609 C CB  . VAL   A 1 299 ? 145.528 150.594 167.369 1.00 9.56   ? 288 VAL   A CB  1 
ATOM   1610 C CG1 . VAL   A 1 299 ? 144.804 151.702 168.108 1.00 14.50  ? 288 VAL   A CG1 1 
ATOM   1611 C CG2 . VAL   A 1 299 ? 147.003 150.572 167.733 1.00 10.04  ? 288 VAL   A CG2 1 
ATOM   1612 N N   . ALA   A 1 300 ? 142.643 149.433 166.718 1.00 13.53  ? 289 ALA   A N   1 
ATOM   1613 C CA  . ALA   A 1 300 ? 141.188 149.529 166.787 1.00 15.80  ? 289 ALA   A CA  1 
ATOM   1614 C C   . ALA   A 1 300 ? 140.572 148.252 167.343 1.00 19.11  ? 289 ALA   A C   1 
ATOM   1615 O O   . ALA   A 1 300 ? 139.591 148.306 168.091 1.00 20.37  ? 289 ALA   A O   1 
ATOM   1616 C CB  . ALA   A 1 300 ? 140.618 149.844 165.406 1.00 13.19  ? 289 ALA   A CB  1 
ATOM   1617 N N   . VAL   A 1 301 ? 141.128 147.094 166.984 1.00 19.38  ? 290 VAL   A N   1 
ATOM   1618 C CA  . VAL   A 1 301 ? 140.634 145.828 167.515 1.00 20.06  ? 290 VAL   A CA  1 
ATOM   1619 C C   . VAL   A 1 301 ? 140.823 145.778 169.023 1.00 23.55  ? 290 VAL   A C   1 
ATOM   1620 O O   . VAL   A 1 301 ? 139.914 145.390 169.766 1.00 29.88  ? 290 VAL   A O   1 
ATOM   1621 C CB  . VAL   A 1 301 ? 141.333 144.647 166.815 1.00 18.67  ? 290 VAL   A CB  1 
ATOM   1622 C CG1 . VAL   A 1 301 ? 141.233 143.386 167.659 1.00 21.55  ? 290 VAL   A CG1 1 
ATOM   1623 C CG2 . VAL   A 1 301 ? 140.732 144.417 165.439 1.00 18.14  ? 290 VAL   A CG2 1 
ATOM   1624 N N   . PHE   A 1 302 ? 142.002 146.183 169.501 1.00 22.94  ? 291 PHE   A N   1 
ATOM   1625 C CA  . PHE   A 1 302 ? 142.241 146.205 170.940 1.00 24.67  ? 291 PHE   A CA  1 
ATOM   1626 C C   . PHE   A 1 302 ? 141.308 147.183 171.639 1.00 26.00  ? 291 PHE   A C   1 
ATOM   1627 O O   . PHE   A 1 302 ? 140.796 146.893 172.725 1.00 34.18  ? 291 PHE   A O   1 
ATOM   1628 C CB  . PHE   A 1 302 ? 143.696 146.562 171.226 1.00 20.57  ? 291 PHE   A CB  1 
ATOM   1629 C CG  . PHE   A 1 302 ? 144.062 146.515 172.685 1.00 23.63  ? 291 PHE   A CG  1 
ATOM   1630 C CD1 . PHE   A 1 302 ? 143.802 147.587 173.521 1.00 28.07  ? 291 PHE   A CD1 1 
ATOM   1631 C CD2 . PHE   A 1 302 ? 144.688 145.403 173.215 1.00 31.65  ? 291 PHE   A CD2 1 
ATOM   1632 C CE1 . PHE   A 1 302 ? 144.144 147.541 174.858 1.00 28.08  ? 291 PHE   A CE1 1 
ATOM   1633 C CE2 . PHE   A 1 302 ? 145.034 145.357 174.550 1.00 29.93  ? 291 PHE   A CE2 1 
ATOM   1634 C CZ  . PHE   A 1 302 ? 144.764 146.427 175.371 1.00 22.65  ? 291 PHE   A CZ  1 
ATOM   1635 N N   . ILE   A 1 303 ? 141.087 148.355 171.042 1.00 20.80  ? 292 ILE   A N   1 
ATOM   1636 C CA  . ILE   A 1 303 ? 140.194 149.338 171.650 1.00 22.31  ? 292 ILE   A CA  1 
ATOM   1637 C C   . ILE   A 1 303 ? 138.780 148.777 171.749 1.00 31.15  ? 292 ILE   A C   1 
ATOM   1638 O O   . ILE   A 1 303 ? 138.136 148.852 172.801 1.00 36.73  ? 292 ILE   A O   1 
ATOM   1639 C CB  . ILE   A 1 303 ? 140.230 150.657 170.860 1.00 21.13  ? 292 ILE   A CB  1 
ATOM   1640 C CG1 . ILE   A 1 303 ? 141.505 151.435 171.188 1.00 22.30  ? 292 ILE   A CG1 1 
ATOM   1641 C CG2 . ILE   A 1 303 ? 139.003 151.497 171.162 1.00 19.65  ? 292 ILE   A CG2 1 
ATOM   1642 C CD1 . ILE   A 1 303 ? 141.760 152.603 170.268 1.00 15.76  ? 292 ILE   A CD1 1 
ATOM   1643 N N   . VAL   A 1 304 ? 138.288 148.181 170.661 1.00 30.56  ? 293 VAL   A N   1 
ATOM   1644 C CA  . VAL   A 1 304 ? 136.957 147.578 170.673 1.00 32.03  ? 293 VAL   A CA  1 
ATOM   1645 C C   . VAL   A 1 304 ? 136.878 146.481 171.726 1.00 29.26  ? 293 VAL   A C   1 
ATOM   1646 O O   . VAL   A 1 304 ? 135.867 146.338 172.423 1.00 33.57  ? 293 VAL   A O   1 
ATOM   1647 C CB  . VAL   A 1 304 ? 136.603 147.048 169.271 1.00 34.99  ? 293 VAL   A CB  1 
ATOM   1648 C CG1 . VAL   A 1 304 ? 135.431 146.079 169.340 1.00 34.37  ? 293 VAL   A CG1 1 
ATOM   1649 C CG2 . VAL   A 1 304 ? 136.292 148.202 168.332 1.00 33.25  ? 293 VAL   A CG2 1 
ATOM   1650 N N   . CYS   A 1 305 ? 137.949 145.698 171.868 1.00 26.29  ? 294 CYS   A N   1 
ATOM   1651 C CA  . CYS   A 1 305 ? 137.927 144.576 172.798 1.00 33.98  ? 294 CYS   A CA  1 
ATOM   1652 C C   . CYS   A 1 305 ? 138.036 145.026 174.250 1.00 39.50  ? 294 CYS   A C   1 
ATOM   1653 O O   . CYS   A 1 305 ? 137.593 144.305 175.151 1.00 43.24  ? 294 CYS   A O   1 
ATOM   1654 C CB  . CYS   A 1 305 ? 139.054 143.601 172.464 1.00 32.72  ? 294 CYS   A CB  1 
ATOM   1655 S SG  . CYS   A 1 305 ? 138.764 142.603 170.987 1.00 50.48  ? 294 CYS   A SG  1 
ATOM   1656 N N   . TRP   A 1 306 ? 138.629 146.191 174.510 1.00 34.66  ? 295 TRP   A N   1 
ATOM   1657 C CA  . TRP   A 1 306 ? 138.924 146.558 175.887 1.00 33.56  ? 295 TRP   A CA  1 
ATOM   1658 C C   . TRP   A 1 306 ? 138.111 147.725 176.427 1.00 39.79  ? 295 TRP   A C   1 
ATOM   1659 O O   . TRP   A 1 306 ? 138.149 147.961 177.638 1.00 46.71  ? 295 TRP   A O   1 
ATOM   1660 C CB  . TRP   A 1 306 ? 140.416 146.874 176.041 1.00 29.93  ? 295 TRP   A CB  1 
ATOM   1661 C CG  . TRP   A 1 306 ? 141.233 145.636 176.147 1.00 28.74  ? 295 TRP   A CG  1 
ATOM   1662 C CD1 . TRP   A 1 306 ? 141.851 144.982 175.128 1.00 32.39  ? 295 TRP   A CD1 1 
ATOM   1663 C CD2 . TRP   A 1 306 ? 141.482 144.867 177.327 1.00 35.36  ? 295 TRP   A CD2 1 
ATOM   1664 N NE1 . TRP   A 1 306 ? 142.496 143.867 175.602 1.00 40.87  ? 295 TRP   A NE1 1 
ATOM   1665 C CE2 . TRP   A 1 306 ? 142.282 143.773 176.951 1.00 41.70  ? 295 TRP   A CE2 1 
ATOM   1666 C CE3 . TRP   A 1 306 ? 141.120 145.004 178.668 1.00 35.48  ? 295 TRP   A CE3 1 
ATOM   1667 C CZ2 . TRP   A 1 306 ? 142.721 142.821 177.865 1.00 45.56  ? 295 TRP   A CZ2 1 
ATOM   1668 C CZ3 . TRP   A 1 306 ? 141.547 144.055 179.570 1.00 33.58  ? 295 TRP   A CZ3 1 
ATOM   1669 C CH2 . TRP   A 1 306 ? 142.347 142.983 179.168 1.00 39.10  ? 295 TRP   A CH2 1 
ATOM   1670 N N   . THR   A 1 307 ? 137.393 148.466 175.583 1.00 36.72  ? 296 THR   A N   1 
ATOM   1671 C CA  . THR   A 1 307 ? 136.461 149.456 176.119 1.00 41.98  ? 296 THR   A CA  1 
ATOM   1672 C C   . THR   A 1 307 ? 135.346 148.857 176.975 1.00 50.77  ? 296 THR   A C   1 
ATOM   1673 O O   . THR   A 1 307 ? 135.032 149.457 178.018 1.00 56.03  ? 296 THR   A O   1 
ATOM   1674 C CB  . THR   A 1 307 ? 135.876 150.327 174.994 1.00 36.54  ? 296 THR   A CB  1 
ATOM   1675 O OG1 . THR   A 1 307 ? 135.184 149.519 174.034 1.00 35.16  ? 296 THR   A OG1 1 
ATOM   1676 C CG2 . THR   A 1 307 ? 136.955 151.158 174.320 1.00 39.52  ? 296 THR   A CG2 1 
ATOM   1677 N N   . PRO   A 1 308 ? 134.701 147.733 176.619 1.00 51.35  ? 297 PRO   A N   1 
ATOM   1678 C CA  . PRO   A 1 308 ? 133.615 147.235 177.484 1.00 55.83  ? 297 PRO   A CA  1 
ATOM   1679 C C   . PRO   A 1 308 ? 134.048 146.937 178.910 1.00 61.03  ? 297 PRO   A C   1 
ATOM   1680 O O   . PRO   A 1 308 ? 133.323 147.268 179.855 1.00 68.78  ? 297 PRO   A O   1 
ATOM   1681 C CB  . PRO   A 1 308 ? 133.147 145.966 176.757 1.00 56.35  ? 297 PRO   A CB  1 
ATOM   1682 C CG  . PRO   A 1 308 ? 133.547 146.160 175.354 1.00 55.74  ? 297 PRO   A CG  1 
ATOM   1683 C CD  . PRO   A 1 308 ? 134.854 146.880 175.426 1.00 52.58  ? 297 PRO   A CD  1 
ATOM   1684 N N   . ILE   A 1 309 ? 135.226 146.338 179.097 1.00 58.79  ? 298 ILE   A N   1 
ATOM   1685 C CA  . ILE   A 1 309 ? 135.621 145.907 180.435 1.00 60.58  ? 298 ILE   A CA  1 
ATOM   1686 C C   . ILE   A 1 309 ? 136.026 147.099 181.296 1.00 57.30  ? 298 ILE   A C   1 
ATOM   1687 O O   . ILE   A 1 309 ? 135.622 147.198 182.458 1.00 61.94  ? 298 ILE   A O   1 
ATOM   1688 C CB  . ILE   A 1 309 ? 136.734 144.846 180.351 1.00 58.17  ? 298 ILE   A CB  1 
ATOM   1689 C CG1 . ILE   A 1 309 ? 137.191 144.430 181.752 1.00 52.83  ? 298 ILE   A CG1 1 
ATOM   1690 C CG2 . ILE   A 1 309 ? 137.887 145.335 179.504 1.00 53.33  ? 298 ILE   A CG2 1 
ATOM   1691 C CD1 . ILE   A 1 309 ? 136.086 143.860 182.612 1.00 61.46  ? 298 ILE   A CD1 1 
ATOM   1692 N N   . HIS   A 1 310 ? 136.820 148.023 180.747 1.00 53.29  ? 299 HIS   A N   1 
ATOM   1693 C CA  . HIS   A 1 310 ? 137.222 149.200 181.513 1.00 56.22  ? 299 HIS   A CA  1 
ATOM   1694 C C   . HIS   A 1 310 ? 136.007 150.021 181.925 1.00 66.48  ? 299 HIS   A C   1 
ATOM   1695 O O   . HIS   A 1 310 ? 135.860 150.404 183.094 1.00 70.43  ? 299 HIS   A O   1 
ATOM   1696 C CB  . HIS   A 1 310 ? 138.188 150.058 180.693 1.00 50.49  ? 299 HIS   A CB  1 
ATOM   1697 C CG  . HIS   A 1 310 ? 139.623 149.647 180.811 1.00 41.00  ? 299 HIS   A CG  1 
ATOM   1698 N ND1 . HIS   A 1 310 ? 140.230 148.797 179.913 1.00 40.22  ? 299 HIS   A ND1 1 
ATOM   1699 C CD2 . HIS   A 1 310 ? 140.574 149.979 181.715 1.00 34.36  ? 299 HIS   A CD2 1 
ATOM   1700 C CE1 . HIS   A 1 310 ? 141.492 148.619 180.260 1.00 34.72  ? 299 HIS   A CE1 1 
ATOM   1701 N NE2 . HIS   A 1 310 ? 141.726 149.325 181.351 1.00 30.92  ? 299 HIS   A NE2 1 
ATOM   1702 N N   . ILE   A 1 311 ? 135.115 150.289 180.968 1.00 66.05  ? 300 ILE   A N   1 
ATOM   1703 C CA  . ILE   A 1 311 ? 133.939 151.109 181.244 1.00 70.38  ? 300 ILE   A CA  1 
ATOM   1704 C C   . ILE   A 1 311 ? 133.007 150.398 182.215 1.00 73.85  ? 300 ILE   A C   1 
ATOM   1705 O O   . ILE   A 1 311 ? 132.446 151.020 183.122 1.00 77.66  ? 300 ILE   A O   1 
ATOM   1706 C CB  . ILE   A 1 311 ? 133.224 151.480 179.930 1.00 63.34  ? 300 ILE   A CB  1 
ATOM   1707 C CG1 . ILE   A 1 311 ? 134.112 152.358 179.038 1.00 57.33  ? 300 ILE   A CG1 1 
ATOM   1708 C CG2 . ILE   A 1 311 ? 131.907 152.186 180.216 1.00 69.08  ? 300 ILE   A CG2 1 
ATOM   1709 C CD1 . ILE   A 1 311 ? 135.144 153.196 179.779 1.00 53.48  ? 300 ILE   A CD1 1 
ATOM   1710 N N   . TYR   A 1 312 ? 132.824 149.086 182.041 1.00 69.68  ? 301 TYR   A N   1 
ATOM   1711 C CA  . TYR   A 1 312 ? 131.969 148.335 182.954 1.00 73.40  ? 301 TYR   A CA  1 
ATOM   1712 C C   . TYR   A 1 312 ? 132.530 148.343 184.370 1.00 79.87  ? 301 TYR   A C   1 
ATOM   1713 O O   . TYR   A 1 312 ? 131.781 148.503 185.340 1.00 85.67  ? 301 TYR   A O   1 
ATOM   1714 C CB  . TYR   A 1 312 ? 131.796 146.902 182.451 1.00 70.32  ? 301 TYR   A CB  1 
ATOM   1715 N N   . VAL   A 1 313 ? 133.848 148.176 184.508 1.00 77.94  ? 302 VAL   A N   1 
ATOM   1716 C CA  . VAL   A 1 313 ? 134.476 148.211 185.825 1.00 78.32  ? 302 VAL   A CA  1 
ATOM   1717 C C   . VAL   A 1 313 ? 134.284 149.576 186.469 1.00 81.23  ? 302 VAL   A C   1 
ATOM   1718 O O   . VAL   A 1 313 ? 133.953 149.679 187.657 1.00 87.15  ? 302 VAL   A O   1 
ATOM   1719 C CB  . VAL   A 1 313 ? 135.967 147.845 185.714 1.00 68.49  ? 302 VAL   A CB  1 
ATOM   1720 C CG1 . VAL   A 1 313 ? 136.724 148.340 186.929 1.00 61.70  ? 302 VAL   A CG1 1 
ATOM   1721 C CG2 . VAL   A 1 313 ? 136.135 146.345 185.556 1.00 71.27  ? 302 VAL   A CG2 1 
ATOM   1722 N N   . ILE   A 1 314 ? 134.490 150.646 185.698 1.00 76.06  ? 303 ILE   A N   1 
ATOM   1723 C CA  . ILE   A 1 314 ? 134.329 151.990 186.244 1.00 77.67  ? 303 ILE   A CA  1 
ATOM   1724 C C   . ILE   A 1 314 ? 132.884 152.223 186.674 1.00 85.17  ? 303 ILE   A C   1 
ATOM   1725 O O   . ILE   A 1 314 ? 132.617 152.722 187.774 1.00 88.17  ? 303 ILE   A O   1 
ATOM   1726 C CB  . ILE   A 1 314 ? 134.795 153.040 185.220 1.00 76.87  ? 303 ILE   A CB  1 
ATOM   1727 C CG1 . ILE   A 1 314 ? 136.323 153.133 185.209 1.00 71.66  ? 303 ILE   A CG1 1 
ATOM   1728 C CG2 . ILE   A 1 314 ? 134.178 154.398 185.520 1.00 87.05  ? 303 ILE   A CG2 1 
ATOM   1729 C CD1 . ILE   A 1 314 ? 136.948 153.146 186.589 1.00 72.32  ? 303 ILE   A CD1 1 
ATOM   1730 N N   . ILE   A 1 315 ? 131.929 151.838 185.824 1.00 86.73  ? 304 ILE   A N   1 
ATOM   1731 C CA  . ILE   A 1 315 ? 130.523 152.122 186.092 1.00 92.68  ? 304 ILE   A CA  1 
ATOM   1732 C C   . ILE   A 1 315 ? 130.022 151.322 187.287 1.00 94.57  ? 304 ILE   A C   1 
ATOM   1733 O O   . ILE   A 1 315 ? 129.312 151.856 188.148 1.00 100.30 ? 304 ILE   A O   1 
ATOM   1734 C CB  . ILE   A 1 315 ? 129.678 151.855 184.832 1.00 93.33  ? 304 ILE   A CB  1 
ATOM   1735 C CG1 . ILE   A 1 315 ? 129.975 152.905 183.759 1.00 89.35  ? 304 ILE   A CG1 1 
ATOM   1736 C CG2 . ILE   A 1 315 ? 128.196 151.837 185.170 1.00 95.39  ? 304 ILE   A CG2 1 
ATOM   1737 C CD1 . ILE   A 1 315 ? 129.490 154.293 184.112 1.00 92.63  ? 304 ILE   A CD1 1 
ATOM   1738 N N   . LYS   A 1 316 ? 130.381 150.037 187.368 1.00 91.45  ? 305 LYS   A N   1 
ATOM   1739 C CA  . LYS   A 1 316 ? 129.887 149.200 188.458 1.00 94.99  ? 305 LYS   A CA  1 
ATOM   1740 C C   . LYS   A 1 316 ? 130.309 149.755 189.813 1.00 98.53  ? 305 LYS   A C   1 
ATOM   1741 O O   . LYS   A 1 316 ? 129.569 149.644 190.796 1.00 102.31 ? 305 LYS   A O   1 
ATOM   1742 C CB  . LYS   A 1 316 ? 130.380 147.764 188.282 1.00 92.64  ? 305 LYS   A CB  1 
ATOM   1743 C CG  . LYS   A 1 316 ? 129.870 146.797 189.338 1.00 98.88  ? 305 LYS   A CG  1 
ATOM   1744 C CD  . LYS   A 1 316 ? 130.556 145.445 189.234 1.00 105.11 ? 305 LYS   A CD  1 
ATOM   1745 C CE  . LYS   A 1 316 ? 130.116 144.516 190.354 1.00 104.74 ? 305 LYS   A CE  1 
ATOM   1746 N NZ  . LYS   A 1 316 ? 130.917 143.261 190.385 1.00 92.22  ? 305 LYS   A NZ  1 
ATOM   1747 N N   . ALA   A 1 317 ? 131.498 150.354 189.885 1.00 95.74  ? 306 ALA   A N   1 
ATOM   1748 C CA  . ALA   A 1 317 ? 131.915 151.021 191.112 1.00 96.92  ? 306 ALA   A CA  1 
ATOM   1749 C C   . ALA   A 1 317 ? 131.237 152.376 191.276 1.00 99.76  ? 306 ALA   A C   1 
ATOM   1750 O O   . ALA   A 1 317 ? 130.929 152.785 192.401 1.00 102.23 ? 306 ALA   A O   1 
ATOM   1751 C CB  . ALA   A 1 317 ? 133.435 151.181 191.133 1.00 92.27  ? 306 ALA   A CB  1 
ATOM   1752 N N   . LEU   A 1 318 ? 130.999 153.085 190.169 1.00 99.56  ? 307 LEU   A N   1 
ATOM   1753 C CA  . LEU   A 1 318 ? 130.482 154.448 190.252 1.00 103.29 ? 307 LEU   A CA  1 
ATOM   1754 C C   . LEU   A 1 318 ? 129.056 154.478 190.794 1.00 108.73 ? 307 LEU   A C   1 
ATOM   1755 O O   . LEU   A 1 318 ? 128.748 155.233 191.724 1.00 112.31 ? 307 LEU   A O   1 
ATOM   1756 C CB  . LEU   A 1 318 ? 130.553 155.118 188.878 1.00 100.55 ? 307 LEU   A CB  1 
ATOM   1757 C CG  . LEU   A 1 318 ? 131.885 155.771 188.501 1.00 99.78  ? 307 LEU   A CG  1 
ATOM   1758 C CD1 . LEU   A 1 318 ? 131.685 156.810 187.409 1.00 97.92  ? 307 LEU   A CD1 1 
ATOM   1759 C CD2 . LEU   A 1 318 ? 132.556 156.390 189.719 1.00 99.38  ? 307 LEU   A CD2 1 
ATOM   1760 N N   . VAL   A 1 319 ? 128.168 153.663 190.226 1.00 109.80 ? 308 VAL   A N   1 
ATOM   1761 C CA  . VAL   A 1 319 ? 126.751 153.742 190.574 1.00 111.54 ? 308 VAL   A CA  1 
ATOM   1762 C C   . VAL   A 1 319 ? 126.332 152.535 191.402 1.00 111.19 ? 308 VAL   A C   1 
ATOM   1763 O O   . VAL   A 1 319 ? 125.155 152.396 191.754 1.00 113.05 ? 308 VAL   A O   1 
ATOM   1764 C CB  . VAL   A 1 319 ? 125.874 153.869 189.314 1.00 109.19 ? 308 VAL   A CB  1 
ATOM   1765 C CG1 . VAL   A 1 319 ? 125.942 155.284 188.759 1.00 103.10 ? 308 VAL   A CG1 1 
ATOM   1766 C CG2 . VAL   A 1 319 ? 126.292 152.853 188.264 1.00 110.09 ? 308 VAL   A CG2 1 
ATOM   1767 N N   . THR   A 1 320 ? 127.291 151.663 191.722 1.00 108.21 ? 309 THR   A N   1 
ATOM   1768 C CA  . THR   A 1 320 ? 127.046 150.486 192.550 1.00 110.90 ? 309 THR   A CA  1 
ATOM   1769 C C   . THR   A 1 320 ? 125.897 149.643 192.008 1.00 116.90 ? 309 THR   A C   1 
ATOM   1770 O O   . THR   A 1 320 ? 124.865 149.494 192.670 1.00 119.21 ? 309 THR   A O   1 
ATOM   1771 C CB  . THR   A 1 320 ? 126.760 150.894 193.999 1.00 108.21 ? 309 THR   A CB  1 
ATOM   1772 N N   . ILE   A 1 321 ? 126.064 149.099 190.806 1.00 116.22 ? 310 ILE   A N   1 
ATOM   1773 C CA  . ILE   A 1 321 ? 125.038 148.273 190.173 1.00 120.04 ? 310 ILE   A CA  1 
ATOM   1774 C C   . ILE   A 1 321 ? 124.831 147.010 191.003 1.00 125.13 ? 310 ILE   A C   1 
ATOM   1775 O O   . ILE   A 1 321 ? 125.803 146.301 191.302 1.00 124.10 ? 310 ILE   A O   1 
ATOM   1776 C CB  . ILE   A 1 321 ? 125.417 147.930 188.724 1.00 117.79 ? 310 ILE   A CB  1 
ATOM   1777 C CG1 . ILE   A 1 321 ? 125.578 149.209 187.899 1.00 112.25 ? 310 ILE   A CG1 1 
ATOM   1778 C CG2 . ILE   A 1 321 ? 124.377 147.013 188.099 1.00 122.84 ? 310 ILE   A CG2 1 
ATOM   1779 C CD1 . ILE   A 1 321 ? 125.927 148.962 186.448 1.00 109.89 ? 310 ILE   A CD1 1 
ATOM   1780 N N   . PRO   A 1 322 ? 123.603 146.693 191.393 1.00 127.34 ? 311 PRO   A N   1 
ATOM   1781 C CA  . PRO   A 1 322 ? 123.350 145.495 192.198 1.00 126.79 ? 311 PRO   A CA  1 
ATOM   1782 C C   . PRO   A 1 322 ? 123.428 144.236 191.340 1.00 129.18 ? 311 PRO   A C   1 
ATOM   1783 O O   . PRO   A 1 322 ? 123.422 144.285 190.111 1.00 126.92 ? 311 PRO   A O   1 
ATOM   1784 C CB  . PRO   A 1 322 ? 121.937 145.731 192.732 1.00 125.54 ? 311 PRO   A CB  1 
ATOM   1785 C CG  . PRO   A 1 322 ? 121.285 146.555 191.677 1.00 126.79 ? 311 PRO   A CG  1 
ATOM   1786 C CD  . PRO   A 1 322 ? 122.365 147.440 191.108 1.00 125.71 ? 311 PRO   A CD  1 
ATOM   1787 N N   . GLU   A 1 323 ? 123.503 143.094 192.019 1.00 132.22 ? 312 GLU   A N   1 
ATOM   1788 C CA  . GLU   A 1 323 ? 123.620 141.817 191.329 1.00 131.94 ? 312 GLU   A CA  1 
ATOM   1789 C C   . GLU   A 1 323 ? 122.339 141.491 190.573 1.00 131.84 ? 312 GLU   A C   1 
ATOM   1790 O O   . GLU   A 1 323 ? 121.230 141.668 191.086 1.00 134.35 ? 312 GLU   A O   1 
ATOM   1791 C CB  . GLU   A 1 323 ? 123.940 140.703 192.326 1.00 129.30 ? 312 GLU   A CB  1 
ATOM   1792 N N   . THR   A 1 324 ? 122.499 141.009 189.343 1.00 129.67 ? 313 THR   A N   1 
ATOM   1793 C CA  . THR   A 1 324 ? 121.368 140.638 188.505 1.00 128.94 ? 313 THR   A CA  1 
ATOM   1794 C C   . THR   A 1 324 ? 121.852 139.661 187.444 1.00 127.83 ? 313 THR   A C   1 
ATOM   1795 O O   . THR   A 1 324 ? 123.053 139.532 187.197 1.00 126.48 ? 313 THR   A O   1 
ATOM   1796 C CB  . THR   A 1 324 ? 120.719 141.864 187.851 1.00 127.61 ? 313 THR   A CB  1 
ATOM   1797 N N   . THR   A 1 325 ? 120.894 138.966 186.826 1.00 128.64 ? 314 THR   A N   1 
ATOM   1798 C CA  . THR   A 1 325 ? 121.235 138.026 185.763 1.00 125.27 ? 314 THR   A CA  1 
ATOM   1799 C C   . THR   A 1 325 ? 121.863 138.747 184.576 1.00 124.36 ? 314 THR   A C   1 
ATOM   1800 O O   . THR   A 1 325 ? 122.890 138.313 184.043 1.00 122.57 ? 314 THR   A O   1 
ATOM   1801 C CB  . THR   A 1 325 ? 119.991 137.252 185.326 1.00 120.31 ? 314 THR   A CB  1 
ATOM   1802 N N   . PHE   A 1 326 ? 121.258 139.861 184.154 1.00 124.08 ? 315 PHE   A N   1 
ATOM   1803 C CA  . PHE   A 1 326 ? 121.806 140.624 183.037 1.00 121.01 ? 315 PHE   A CA  1 
ATOM   1804 C C   . PHE   A 1 326 ? 123.181 141.185 183.375 1.00 120.89 ? 315 PHE   A C   1 
ATOM   1805 O O   . PHE   A 1 326 ? 124.088 141.173 182.535 1.00 118.45 ? 315 PHE   A O   1 
ATOM   1806 C CB  . PHE   A 1 326 ? 120.846 141.749 182.648 1.00 121.68 ? 315 PHE   A CB  1 
ATOM   1807 C CG  . PHE   A 1 326 ? 121.518 142.920 181.986 1.00 120.90 ? 315 PHE   A CG  1 
ATOM   1808 C CD1 . PHE   A 1 326 ? 122.012 142.816 180.695 1.00 120.68 ? 315 PHE   A CD1 1 
ATOM   1809 C CD2 . PHE   A 1 326 ? 121.654 144.126 182.654 1.00 118.28 ? 315 PHE   A CD2 1 
ATOM   1810 C CE1 . PHE   A 1 326 ? 122.630 143.891 180.085 1.00 116.81 ? 315 PHE   A CE1 1 
ATOM   1811 C CE2 . PHE   A 1 326 ? 122.271 145.205 182.048 1.00 117.99 ? 315 PHE   A CE2 1 
ATOM   1812 C CZ  . PHE   A 1 326 ? 122.759 145.086 180.762 1.00 115.37 ? 315 PHE   A CZ  1 
ATOM   1813 N N   . GLN   A 1 327 ? 123.352 141.688 184.600 1.00 124.23 ? 316 GLN   A N   1 
ATOM   1814 C CA  . GLN   A 1 327 ? 124.647 142.219 185.012 1.00 124.60 ? 316 GLN   A CA  1 
ATOM   1815 C C   . GLN   A 1 327 ? 125.711 141.128 185.014 1.00 120.98 ? 316 GLN   A C   1 
ATOM   1816 O O   . GLN   A 1 327 ? 126.838 141.341 184.552 1.00 118.66 ? 316 GLN   A O   1 
ATOM   1817 C CB  . GLN   A 1 327 ? 124.526 142.870 186.392 1.00 126.16 ? 316 GLN   A CB  1 
ATOM   1818 C CG  . GLN   A 1 327 ? 125.829 142.960 187.172 1.00 126.62 ? 316 GLN   A CG  1 
ATOM   1819 C CD  . GLN   A 1 327 ? 126.024 141.795 188.124 1.00 127.99 ? 316 GLN   A CD  1 
ATOM   1820 O OE1 . GLN   A 1 327 ? 125.068 141.113 188.491 1.00 127.93 ? 316 GLN   A OE1 1 
ATOM   1821 N NE2 . GLN   A 1 327 ? 127.268 141.562 188.528 1.00 126.82 ? 316 GLN   A NE2 1 
ATOM   1822 N N   . THR   A 1 328 ? 125.367 139.946 185.531 1.00 120.67 ? 317 THR   A N   1 
ATOM   1823 C CA  . THR   A 1 328 ? 126.318 138.838 185.545 1.00 118.77 ? 317 THR   A CA  1 
ATOM   1824 C C   . THR   A 1 328 ? 126.682 138.405 184.130 1.00 114.41 ? 317 THR   A C   1 
ATOM   1825 O O   . THR   A 1 328 ? 127.852 138.129 183.838 1.00 110.22 ? 317 THR   A O   1 
ATOM   1826 C CB  . THR   A 1 328 ? 125.745 137.661 186.333 1.00 118.36 ? 317 THR   A CB  1 
ATOM   1827 N N   . VAL   A 1 329 ? 125.691 138.342 183.237 1.00 116.56 ? 318 VAL   A N   1 
ATOM   1828 C CA  . VAL   A 1 329 ? 125.963 137.958 181.854 1.00 115.27 ? 318 VAL   A CA  1 
ATOM   1829 C C   . VAL   A 1 329 ? 126.860 138.987 181.180 1.00 111.03 ? 318 VAL   A C   1 
ATOM   1830 O O   . VAL   A 1 329 ? 127.789 138.633 180.445 1.00 106.33 ? 318 VAL   A O   1 
ATOM   1831 C CB  . VAL   A 1 329 ? 124.645 137.755 181.083 1.00 115.79 ? 318 VAL   A CB  1 
ATOM   1832 C CG1 . VAL   A 1 329 ? 124.916 137.590 179.597 1.00 110.59 ? 318 VAL   A CG1 1 
ATOM   1833 C CG2 . VAL   A 1 329 ? 123.904 136.540 181.618 1.00 115.39 ? 318 VAL   A CG2 1 
ATOM   1834 N N   . SER   A 1 330 ? 126.600 140.276 181.416 1.00 111.79 ? 319 SER   A N   1 
ATOM   1835 C CA  . SER   A 1 330 ? 127.437 141.319 180.829 1.00 108.52 ? 319 SER   A CA  1 
ATOM   1836 C C   . SER   A 1 330 ? 128.864 141.249 181.361 1.00 104.93 ? 319 SER   A C   1 
ATOM   1837 O O   . SER   A 1 330 ? 129.824 141.416 180.602 1.00 98.11  ? 319 SER   A O   1 
ATOM   1838 C CB  . SER   A 1 330 ? 126.830 142.696 181.098 1.00 108.19 ? 319 SER   A CB  1 
ATOM   1839 O OG  . SER   A 1 330 ? 126.751 142.959 182.488 1.00 109.45 ? 319 SER   A OG  1 
ATOM   1840 N N   . TRP   A 1 331 ? 129.020 141.007 182.665 1.00 110.06 ? 320 TRP   A N   1 
ATOM   1841 C CA  . TRP   A 1 331 ? 130.349 140.871 183.253 1.00 107.02 ? 320 TRP   A CA  1 
ATOM   1842 C C   . TRP   A 1 331 ? 131.100 139.693 182.642 1.00 101.44 ? 320 TRP   A C   1 
ATOM   1843 O O   . TRP   A 1 331 ? 132.277 139.808 182.268 1.00 97.60  ? 320 TRP   A O   1 
ATOM   1844 C CB  . TRP   A 1 331 ? 130.212 140.707 184.768 1.00 106.23 ? 320 TRP   A CB  1 
ATOM   1845 C CG  . TRP   A 1 331 ? 131.495 140.726 185.536 1.00 100.59 ? 320 TRP   A CG  1 
ATOM   1846 C CD1 . TRP   A 1 331 ? 132.117 139.658 186.115 1.00 99.79  ? 320 TRP   A CD1 1 
ATOM   1847 C CD2 . TRP   A 1 331 ? 132.301 141.871 185.838 1.00 97.73  ? 320 TRP   A CD2 1 
ATOM   1848 N NE1 . TRP   A 1 331 ? 133.265 140.065 186.749 1.00 95.33  ? 320 TRP   A NE1 1 
ATOM   1849 C CE2 . TRP   A 1 331 ? 133.402 141.419 186.592 1.00 98.21  ? 320 TRP   A CE2 1 
ATOM   1850 C CE3 . TRP   A 1 331 ? 132.202 143.233 185.538 1.00 98.09  ? 320 TRP   A CE3 1 
ATOM   1851 C CZ2 . TRP   A 1 331 ? 134.397 142.279 187.050 1.00 97.65  ? 320 TRP   A CZ2 1 
ATOM   1852 C CZ3 . TRP   A 1 331 ? 133.191 144.085 185.994 1.00 95.73  ? 320 TRP   A CZ3 1 
ATOM   1853 C CH2 . TRP   A 1 331 ? 134.273 143.605 186.742 1.00 97.36  ? 320 TRP   A CH2 1 
ATOM   1854 N N   . HIS   A 1 332 ? 130.420 138.549 182.523 1.00 101.04 ? 321 HIS   A N   1 
ATOM   1855 C CA  . HIS   A 1 332 ? 131.039 137.372 181.925 1.00 98.38  ? 321 HIS   A CA  1 
ATOM   1856 C C   . HIS   A 1 332 ? 131.431 137.633 180.478 1.00 90.60  ? 321 HIS   A C   1 
ATOM   1857 O O   . HIS   A 1 332 ? 132.528 137.261 180.050 1.00 84.43  ? 321 HIS   A O   1 
ATOM   1858 C CB  . HIS   A 1 332 ? 130.090 136.178 182.015 1.00 104.19 ? 321 HIS   A CB  1 
ATOM   1859 C CG  . HIS   A 1 332 ? 130.399 135.243 183.142 1.00 108.72 ? 321 HIS   A CG  1 
ATOM   1860 N ND1 . HIS   A 1 332 ? 130.216 135.586 184.465 1.00 113.36 ? 321 HIS   A ND1 1 
ATOM   1861 C CD2 . HIS   A 1 332 ? 130.876 133.976 183.144 1.00 105.63 ? 321 HIS   A CD2 1 
ATOM   1862 C CE1 . HIS   A 1 332 ? 130.569 134.571 185.233 1.00 117.54 ? 321 HIS   A CE1 1 
ATOM   1863 N NE2 . HIS   A 1 332 ? 130.974 133.582 184.456 1.00 111.04 ? 321 HIS   A NE2 1 
ATOM   1864 N N   . PHE   A 1 333 ? 130.547 138.276 179.711 1.00 91.05  ? 322 PHE   A N   1 
ATOM   1865 C CA  . PHE   A 1 333 ? 130.846 138.567 178.313 1.00 91.53  ? 322 PHE   A CA  1 
ATOM   1866 C C   . PHE   A 1 333 ? 132.028 139.518 178.186 1.00 86.99  ? 322 PHE   A C   1 
ATOM   1867 O O   . PHE   A 1 333 ? 132.895 139.327 177.326 1.00 82.57  ? 322 PHE   A O   1 
ATOM   1868 C CB  . PHE   A 1 333 ? 129.614 139.154 177.624 1.00 96.41  ? 322 PHE   A CB  1 
ATOM   1869 C CG  . PHE   A 1 333 ? 129.922 139.877 176.342 1.00 93.00  ? 322 PHE   A CG  1 
ATOM   1870 C CD1 . PHE   A 1 333 ? 130.393 139.188 175.237 1.00 86.66  ? 322 PHE   A CD1 1 
ATOM   1871 C CD2 . PHE   A 1 333 ? 129.745 141.248 176.245 1.00 90.58  ? 322 PHE   A CD2 1 
ATOM   1872 C CE1 . PHE   A 1 333 ? 130.678 139.851 174.059 1.00 88.60  ? 322 PHE   A CE1 1 
ATOM   1873 C CE2 . PHE   A 1 333 ? 130.028 141.917 175.070 1.00 88.74  ? 322 PHE   A CE2 1 
ATOM   1874 C CZ  . PHE   A 1 333 ? 130.495 141.217 173.975 1.00 90.98  ? 322 PHE   A CZ  1 
ATOM   1875 N N   . CYS   A 1 334 ? 132.079 140.551 179.030 1.00 85.85  ? 323 CYS   A N   1 
ATOM   1876 C CA  . CYS   A 1 334 ? 133.180 141.505 178.967 1.00 82.17  ? 323 CYS   A CA  1 
ATOM   1877 C C   . CYS   A 1 334 ? 134.509 140.827 179.268 1.00 75.52  ? 323 CYS   A C   1 
ATOM   1878 O O   . CYS   A 1 334 ? 135.489 141.003 178.534 1.00 67.71  ? 323 CYS   A O   1 
ATOM   1879 C CB  . CYS   A 1 334 ? 132.930 142.660 179.938 1.00 77.61  ? 323 CYS   A CB  1 
ATOM   1880 S SG  . CYS   A 1 334 ? 131.656 143.826 179.404 1.00 79.74  ? 323 CYS   A SG  1 
ATOM   1881 N N   . ILE   A 1 335 ? 134.557 140.029 180.339 1.00 79.00  ? 324 ILE   A N   1 
ATOM   1882 C CA  . ILE   A 1 335 ? 135.800 139.336 180.672 1.00 74.22  ? 324 ILE   A CA  1 
ATOM   1883 C C   . ILE   A 1 335 ? 136.182 138.363 179.564 1.00 72.46  ? 324 ILE   A C   1 
ATOM   1884 O O   . ILE   A 1 335 ? 137.349 138.291 179.152 1.00 69.20  ? 324 ILE   A O   1 
ATOM   1885 C CB  . ILE   A 1 335 ? 135.675 138.627 182.033 1.00 72.79  ? 324 ILE   A CB  1 
ATOM   1886 C CG1 . ILE   A 1 335 ? 135.532 139.651 183.156 1.00 72.82  ? 324 ILE   A CG1 1 
ATOM   1887 C CG2 . ILE   A 1 335 ? 136.883 137.746 182.288 1.00 70.08  ? 324 ILE   A CG2 1 
ATOM   1888 C CD1 . ILE   A 1 335 ? 135.321 139.027 184.509 1.00 73.71  ? 324 ILE   A CD1 1 
ATOM   1889 N N   . ALA   A 1 336 ? 135.203 137.607 179.055 1.00 73.13  ? 325 ALA   A N   1 
ATOM   1890 C CA  . ALA   A 1 336 ? 135.482 136.607 178.033 1.00 67.47  ? 325 ALA   A CA  1 
ATOM   1891 C C   . ALA   A 1 336 ? 136.005 137.247 176.756 1.00 66.41  ? 325 ALA   A C   1 
ATOM   1892 O O   . ALA   A 1 336 ? 136.933 136.727 176.136 1.00 63.38  ? 325 ALA   A O   1 
ATOM   1893 C CB  . ALA   A 1 336 ? 134.225 135.787 177.746 1.00 68.88  ? 325 ALA   A CB  1 
ATOM   1894 N N   . LEU   A 1 337 ? 135.428 138.379 176.350 1.00 68.76  ? 326 LEU   A N   1 
ATOM   1895 C CA  . LEU   A 1 337 ? 135.876 139.040 175.127 1.00 65.64  ? 326 LEU   A CA  1 
ATOM   1896 C C   . LEU   A 1 337 ? 137.236 139.704 175.320 1.00 58.74  ? 326 LEU   A C   1 
ATOM   1897 O O   . LEU   A 1 337 ? 138.083 139.675 174.414 1.00 54.76  ? 326 LEU   A O   1 
ATOM   1898 C CB  . LEU   A 1 337 ? 134.818 140.047 174.673 1.00 65.08  ? 326 LEU   A CB  1 
ATOM   1899 C CG  . LEU   A 1 337 ? 135.151 141.058 173.580 1.00 57.31  ? 326 LEU   A CG  1 
ATOM   1900 C CD1 . LEU   A 1 337 ? 134.042 141.093 172.549 1.00 63.93  ? 326 LEU   A CD1 1 
ATOM   1901 C CD2 . LEU   A 1 337 ? 135.313 142.425 174.199 1.00 47.43  ? 326 LEU   A CD2 1 
ATOM   1902 N N   . GLY   A 1 338 ? 137.472 140.294 176.495 1.00 58.26  ? 327 GLY   A N   1 
ATOM   1903 C CA  . GLY   A 1 338 ? 138.788 140.843 176.777 1.00 54.35  ? 327 GLY   A CA  1 
ATOM   1904 C C   . GLY   A 1 338 ? 139.873 139.785 176.744 1.00 53.36  ? 327 GLY   A C   1 
ATOM   1905 O O   . GLY   A 1 338 ? 140.993 140.043 176.296 1.00 46.96  ? 327 GLY   A O   1 
ATOM   1906 N N   . TYR   A 1 339 ? 139.559 138.579 177.221 1.00 55.33  ? 328 TYR   A N   1 
ATOM   1907 C CA  . TYR   A 1 339 ? 140.510 137.479 177.116 1.00 50.45  ? 328 TYR   A CA  1 
ATOM   1908 C C   . TYR   A 1 339 ? 140.613 136.944 175.693 1.00 51.30  ? 328 TYR   A C   1 
ATOM   1909 O O   . TYR   A 1 339 ? 141.708 136.587 175.245 1.00 53.65  ? 328 TYR   A O   1 
ATOM   1910 C CB  . TYR   A 1 339 ? 140.119 136.354 178.073 1.00 53.76  ? 328 TYR   A CB  1 
ATOM   1911 C CG  . TYR   A 1 339 ? 140.708 136.493 179.457 1.00 56.57  ? 328 TYR   A CG  1 
ATOM   1912 C CD1 . TYR   A 1 339 ? 142.078 136.396 179.662 1.00 54.03  ? 328 TYR   A CD1 1 
ATOM   1913 C CD2 . TYR   A 1 339 ? 139.896 136.721 180.558 1.00 59.89  ? 328 TYR   A CD2 1 
ATOM   1914 C CE1 . TYR   A 1 339 ? 142.620 136.519 180.924 1.00 52.34  ? 328 TYR   A CE1 1 
ATOM   1915 C CE2 . TYR   A 1 339 ? 140.429 136.845 181.823 1.00 57.13  ? 328 TYR   A CE2 1 
ATOM   1916 C CZ  . TYR   A 1 339 ? 141.790 136.743 182.001 1.00 55.10  ? 328 TYR   A CZ  1 
ATOM   1917 O OH  . TYR   A 1 339 ? 142.323 136.868 183.262 1.00 57.77  ? 328 TYR   A OH  1 
ATOM   1918 N N   . THR   A 1 340 ? 139.491 136.889 174.973 1.00 53.52  ? 329 THR   A N   1 
ATOM   1919 C CA  . THR   A 1 340 ? 139.441 136.383 173.609 1.00 54.30  ? 329 THR   A CA  1 
ATOM   1920 C C   . THR   A 1 340 ? 140.235 137.250 172.643 1.00 47.65  ? 329 THR   A C   1 
ATOM   1921 O O   . THR   A 1 340 ? 140.722 136.740 171.629 1.00 49.74  ? 329 THR   A O   1 
ATOM   1922 C CB  . THR   A 1 340 ? 137.971 136.274 173.174 1.00 57.88  ? 329 THR   A CB  1 
ATOM   1923 O OG1 . THR   A 1 340 ? 137.375 135.128 173.795 1.00 57.46  ? 329 THR   A OG1 1 
ATOM   1924 C CG2 . THR   A 1 340 ? 137.826 136.142 171.664 1.00 57.96  ? 329 THR   A CG2 1 
ATOM   1925 N N   . ASN   A 1 341 ? 140.402 138.537 172.955 1.00 46.06  ? 330 ASN   A N   1 
ATOM   1926 C CA  . ASN   A 1 341 ? 141.246 139.398 172.128 1.00 42.28  ? 330 ASN   A CA  1 
ATOM   1927 C C   . ASN   A 1 341 ? 142.639 138.807 171.930 1.00 40.69  ? 330 ASN   A C   1 
ATOM   1928 O O   . ASN   A 1 341 ? 143.253 138.991 170.868 1.00 47.00  ? 330 ASN   A O   1 
ATOM   1929 C CB  . ASN   A 1 341 ? 141.347 140.786 172.764 1.00 40.28  ? 330 ASN   A CB  1 
ATOM   1930 C CG  . ASN   A 1 341 ? 142.307 141.694 172.031 1.00 32.41  ? 330 ASN   A CG  1 
ATOM   1931 O OD1 . ASN   A 1 341 ? 143.424 141.932 172.487 1.00 32.04  ? 330 ASN   A OD1 1 
ATOM   1932 N ND2 . ASN   A 1 341 ? 141.877 142.211 170.888 1.00 33.40  ? 330 ASN   A ND2 1 
ATOM   1933 N N   . SER   A 1 342 ? 143.146 138.085 172.932 1.00 36.26  ? 331 SER   A N   1 
ATOM   1934 C CA  . SER   A 1 342 ? 144.477 137.496 172.833 1.00 40.40  ? 331 SER   A CA  1 
ATOM   1935 C C   . SER   A 1 342 ? 144.558 136.482 171.698 1.00 50.94  ? 331 SER   A C   1 
ATOM   1936 O O   . SER   A 1 342 ? 145.552 136.441 170.964 1.00 57.56  ? 331 SER   A O   1 
ATOM   1937 C CB  . SER   A 1 342 ? 144.858 136.845 174.160 1.00 42.40  ? 331 SER   A CB  1 
ATOM   1938 O OG  . SER   A 1 342 ? 144.473 137.657 175.255 1.00 44.67  ? 331 SER   A OG  1 
ATOM   1939 N N   . CYS   A 1 343 ? 143.533 135.646 171.547 1.00 49.54  ? 332 CYS   A N   1 
ATOM   1940 C CA  . CYS   A 1 343 ? 143.469 134.715 170.429 1.00 48.20  ? 332 CYS   A CA  1 
ATOM   1941 C C   . CYS   A 1 343 ? 142.992 135.374 169.143 1.00 45.38  ? 332 CYS   A C   1 
ATOM   1942 O O   . CYS   A 1 343 ? 143.234 134.834 168.059 1.00 51.42  ? 332 CYS   A O   1 
ATOM   1943 C CB  . CYS   A 1 343 ? 142.552 133.535 170.771 1.00 53.44  ? 332 CYS   A CB  1 
ATOM   1944 S SG  . CYS   A 1 343 ? 140.796 133.830 170.478 1.00 58.37  ? 332 CYS   A SG  1 
ATOM   1945 N N   . LEU   A 1 344 ? 142.315 136.519 169.241 1.00 41.66  ? 333 LEU   A N   1 
ATOM   1946 C CA  . LEU   A 1 344 ? 141.871 137.241 168.055 1.00 36.83  ? 333 LEU   A CA  1 
ATOM   1947 C C   . LEU   A 1 344 ? 143.026 137.921 167.337 1.00 37.15  ? 333 LEU   A C   1 
ATOM   1948 O O   . LEU   A 1 344 ? 142.978 138.080 166.113 1.00 43.13  ? 333 LEU   A O   1 
ATOM   1949 C CB  . LEU   A 1 344 ? 140.817 138.282 168.432 1.00 37.96  ? 333 LEU   A CB  1 
ATOM   1950 C CG  . LEU   A 1 344 ? 139.416 137.785 168.788 1.00 41.23  ? 333 LEU   A CG  1 
ATOM   1951 C CD1 . LEU   A 1 344 ? 138.376 138.829 168.414 1.00 45.56  ? 333 LEU   A CD1 1 
ATOM   1952 C CD2 . LEU   A 1 344 ? 139.112 136.456 168.113 1.00 41.96  ? 333 LEU   A CD2 1 
ATOM   1953 N N   . ASN   A 1 345 ? 144.049 138.342 168.076 1.00 37.21  ? 334 ASN   A N   1 
ATOM   1954 C CA  . ASN   A 1 345 ? 145.192 139.017 167.458 1.00 40.81  ? 334 ASN   A CA  1 
ATOM   1955 C C   . ASN   A 1 345 ? 145.869 138.201 166.358 1.00 48.73  ? 334 ASN   A C   1 
ATOM   1956 O O   . ASN   A 1 345 ? 146.109 138.760 165.272 1.00 54.21  ? 334 ASN   A O   1 
ATOM   1957 C CB  . ASN   A 1 345 ? 146.199 139.412 168.548 1.00 40.81  ? 334 ASN   A CB  1 
ATOM   1958 C CG  . ASN   A 1 345 ? 145.858 140.730 169.209 1.00 42.94  ? 334 ASN   A CG  1 
ATOM   1959 O OD1 . ASN   A 1 345 ? 145.270 141.615 168.589 1.00 42.05  ? 334 ASN   A OD1 1 
ATOM   1960 N ND2 . ASN   A 1 345 ? 146.224 140.868 170.477 1.00 45.28  ? 334 ASN   A ND2 1 
ATOM   1961 N N   . PRO   A 1 346 ? 146.199 136.912 166.549 1.00 50.86  ? 335 PRO   A N   1 
ATOM   1962 C CA  . PRO   A 1 346 ? 146.852 136.168 165.454 1.00 53.88  ? 335 PRO   A CA  1 
ATOM   1963 C C   . PRO   A 1 346 ? 146.030 136.117 164.180 1.00 48.81  ? 335 PRO   A C   1 
ATOM   1964 O O   . PRO   A 1 346 ? 146.597 136.128 163.081 1.00 49.88  ? 335 PRO   A O   1 
ATOM   1965 C CB  . PRO   A 1 346 ? 147.053 134.769 166.052 1.00 55.55  ? 335 PRO   A CB  1 
ATOM   1966 C CG  . PRO   A 1 346 ? 147.072 134.979 167.514 1.00 57.10  ? 335 PRO   A CG  1 
ATOM   1967 C CD  . PRO   A 1 346 ? 146.126 136.105 167.781 1.00 48.63  ? 335 PRO   A CD  1 
ATOM   1968 N N   . VAL   A 1 347 ? 144.702 136.063 164.297 1.00 44.26  ? 336 VAL   A N   1 
ATOM   1969 C CA  . VAL   A 1 347 ? 143.851 136.106 163.113 1.00 44.38  ? 336 VAL   A CA  1 
ATOM   1970 C C   . VAL   A 1 347 ? 144.065 137.410 162.356 1.00 46.81  ? 336 VAL   A C   1 
ATOM   1971 O O   . VAL   A 1 347 ? 144.178 137.420 161.124 1.00 49.94  ? 336 VAL   A O   1 
ATOM   1972 C CB  . VAL   A 1 347 ? 142.375 135.918 163.510 1.00 40.91  ? 336 VAL   A CB  1 
ATOM   1973 C CG1 . VAL   A 1 347 ? 141.477 136.020 162.289 1.00 47.85  ? 336 VAL   A CG1 1 
ATOM   1974 C CG2 . VAL   A 1 347 ? 142.180 134.585 164.212 1.00 33.38  ? 336 VAL   A CG2 1 
ATOM   1975 N N   . LEU   A 1 348 ? 144.123 138.531 163.082 1.00 45.72  ? 337 LEU   A N   1 
ATOM   1976 C CA  . LEU   A 1 348 ? 144.342 139.821 162.437 1.00 44.83  ? 337 LEU   A CA  1 
ATOM   1977 C C   . LEU   A 1 348 ? 145.702 139.876 161.756 1.00 48.92  ? 337 LEU   A C   1 
ATOM   1978 O O   . LEU   A 1 348 ? 145.815 140.351 160.618 1.00 50.00  ? 337 LEU   A O   1 
ATOM   1979 C CB  . LEU   A 1 348 ? 144.206 140.949 163.458 1.00 36.24  ? 337 LEU   A CB  1 
ATOM   1980 N N   . TYR   A 1 349 ? 146.750 139.386 162.428 1.00 50.96  ? 338 TYR   A N   1 
ATOM   1981 C CA  . TYR   A 1 349 ? 148.069 139.398 161.798 1.00 54.56  ? 338 TYR   A CA  1 
ATOM   1982 C C   . TYR   A 1 349 ? 148.092 138.530 160.545 1.00 63.50  ? 338 TYR   A C   1 
ATOM   1983 O O   . TYR   A 1 349 ? 148.689 138.910 159.530 1.00 66.23  ? 338 TYR   A O   1 
ATOM   1984 C CB  . TYR   A 1 349 ? 149.156 138.942 162.775 1.00 55.48  ? 338 TYR   A CB  1 
ATOM   1985 C CG  . TYR   A 1 349 ? 149.140 139.632 164.119 1.00 56.94  ? 338 TYR   A CG  1 
ATOM   1986 C CD1 . TYR   A 1 349 ? 149.199 141.016 164.213 1.00 52.27  ? 338 TYR   A CD1 1 
ATOM   1987 C CD2 . TYR   A 1 349 ? 149.069 138.899 165.295 1.00 56.11  ? 338 TYR   A CD2 1 
ATOM   1988 C CE1 . TYR   A 1 349 ? 149.185 141.649 165.441 1.00 49.54  ? 338 TYR   A CE1 1 
ATOM   1989 C CE2 . TYR   A 1 349 ? 149.055 139.523 166.526 1.00 48.92  ? 338 TYR   A CE2 1 
ATOM   1990 C CZ  . TYR   A 1 349 ? 149.113 140.897 166.594 1.00 44.41  ? 338 TYR   A CZ  1 
ATOM   1991 O OH  . TYR   A 1 349 ? 149.099 141.521 167.820 1.00 39.36  ? 338 TYR   A OH  1 
ATOM   1992 N N   . ALA   A 1 350 ? 147.452 137.359 160.596 1.00 62.31  ? 339 ALA   A N   1 
ATOM   1993 C CA  . ALA   A 1 350 ? 147.424 136.480 159.431 1.00 61.40  ? 339 ALA   A CA  1 
ATOM   1994 C C   . ALA   A 1 350 ? 146.654 137.106 158.275 1.00 60.71  ? 339 ALA   A C   1 
ATOM   1995 O O   . ALA   A 1 350 ? 147.088 137.028 157.120 1.00 64.46  ? 339 ALA   A O   1 
ATOM   1996 C CB  . ALA   A 1 350 ? 146.813 135.131 159.806 1.00 61.12  ? 339 ALA   A CB  1 
ATOM   1997 N N   . PHE   A 1 351 ? 145.518 137.734 158.563 1.00 57.34  ? 340 PHE   A N   1 
ATOM   1998 C CA  . PHE   A 1 351 ? 144.639 138.260 157.528 1.00 54.33  ? 340 PHE   A CA  1 
ATOM   1999 C C   . PHE   A 1 351 ? 145.057 139.632 157.018 1.00 56.22  ? 340 PHE   A C   1 
ATOM   2000 O O   . PHE   A 1 351 ? 144.518 140.085 156.004 1.00 57.15  ? 340 PHE   A O   1 
ATOM   2001 C CB  . PHE   A 1 351 ? 143.198 138.333 158.048 1.00 48.53  ? 340 PHE   A CB  1 
ATOM   2002 C CG  . PHE   A 1 351 ? 142.527 136.994 158.183 1.00 51.20  ? 340 PHE   A CG  1 
ATOM   2003 C CD1 . PHE   A 1 351 ? 143.205 135.823 157.889 1.00 57.48  ? 340 PHE   A CD1 1 
ATOM   2004 C CD2 . PHE   A 1 351 ? 141.213 136.909 158.613 1.00 53.67  ? 340 PHE   A CD2 1 
ATOM   2005 C CE1 . PHE   A 1 351 ? 142.585 134.594 158.016 1.00 62.28  ? 340 PHE   A CE1 1 
ATOM   2006 C CE2 . PHE   A 1 351 ? 140.588 135.683 158.743 1.00 59.45  ? 340 PHE   A CE2 1 
ATOM   2007 C CZ  . PHE   A 1 351 ? 141.275 134.524 158.444 1.00 61.61  ? 340 PHE   A CZ  1 
ATOM   2008 N N   . LEU   A 1 352 ? 145.998 140.309 157.686 1.00 56.73  ? 341 LEU   A N   1 
ATOM   2009 C CA  . LEU   A 1 352 ? 146.317 141.676 157.288 1.00 53.62  ? 341 LEU   A CA  1 
ATOM   2010 C C   . LEU   A 1 352 ? 147.805 141.904 157.040 1.00 58.85  ? 341 LEU   A C   1 
ATOM   2011 O O   . LEU   A 1 352 ? 148.260 143.052 157.095 1.00 52.65  ? 341 LEU   A O   1 
ATOM   2012 C CB  . LEU   A 1 352 ? 145.819 142.658 158.343 1.00 46.55  ? 341 LEU   A CB  1 
ATOM   2013 C CG  . LEU   A 1 352 ? 144.303 142.815 158.371 1.00 42.23  ? 341 LEU   A CG  1 
ATOM   2014 C CD1 . LEU   A 1 352 ? 143.872 143.327 159.719 1.00 38.42  ? 341 LEU   A CD1 1 
ATOM   2015 C CD2 . LEU   A 1 352 ? 143.844 143.753 157.268 1.00 38.76  ? 341 LEU   A CD2 1 
ATOM   2016 N N   . ASP   A 1 353 ? 148.575 140.853 156.768 1.00 66.84  ? 342 ASP   A N   1 
ATOM   2017 C CA  . ASP   A 1 353 ? 149.983 141.020 156.435 1.00 75.76  ? 342 ASP   A CA  1 
ATOM   2018 C C   . ASP   A 1 353 ? 150.443 139.823 155.619 1.00 80.77  ? 342 ASP   A C   1 
ATOM   2019 O O   . ASP   A 1 353 ? 150.268 138.676 156.043 1.00 80.09  ? 342 ASP   A O   1 
ATOM   2020 C CB  . ASP   A 1 353 ? 150.835 141.175 157.699 1.00 75.18  ? 342 ASP   A CB  1 
ATOM   2021 C CG  . ASP   A 1 353 ? 152.297 141.420 157.390 1.00 79.39  ? 342 ASP   A CG  1 
ATOM   2022 O OD1 . ASP   A 1 353 ? 153.027 140.438 157.145 1.00 87.08  ? 342 ASP   A OD1 1 
ATOM   2023 O OD2 . ASP   A 1 353 ? 152.720 142.595 157.405 1.00 69.91  ? 342 ASP   A OD2 1 
ATOM   2024 N N   . GLU   A 1 354 ? 151.027 140.097 154.449 1.00 83.89  ? 343 GLU   A N   1 
ATOM   2025 C CA  . GLU   A 1 354 ? 151.454 139.022 153.560 1.00 93.31  ? 343 GLU   A CA  1 
ATOM   2026 C C   . GLU   A 1 354 ? 152.584 138.204 154.174 1.00 96.23  ? 343 GLU   A C   1 
ATOM   2027 O O   . GLU   A 1 354 ? 152.590 136.971 154.078 1.00 94.00  ? 343 GLU   A O   1 
ATOM   2028 C CB  . GLU   A 1 354 ? 151.882 139.599 152.211 1.00 96.44  ? 343 GLU   A CB  1 
ATOM   2029 N N   . ASN   A 1 355 ? 153.555 138.873 154.802 1.00 94.93  ? 344 ASN   A N   1 
ATOM   2030 C CA  . ASN   A 1 355 ? 154.679 138.159 155.399 1.00 94.58  ? 344 ASN   A CA  1 
ATOM   2031 C C   . ASN   A 1 355 ? 154.213 137.255 156.533 1.00 94.41  ? 344 ASN   A C   1 
ATOM   2032 O O   . ASN   A 1 355 ? 154.667 136.111 156.659 1.00 99.58  ? 344 ASN   A O   1 
ATOM   2033 C CB  . ASN   A 1 355 ? 155.728 139.154 155.898 1.00 89.71  ? 344 ASN   A CB  1 
ATOM   2034 C CG  . ASN   A 1 355 ? 156.352 139.957 154.775 1.00 87.58  ? 344 ASN   A CG  1 
ATOM   2035 O OD1 . ASN   A 1 355 ? 155.987 139.804 153.610 1.00 82.65  ? 344 ASN   A OD1 1 
ATOM   2036 N ND2 . ASN   A 1 355 ? 157.302 140.818 155.120 1.00 92.37  ? 344 ASN   A ND2 1 
ATOM   2037 N N   . PHE   A 1 356 ? 153.303 137.755 157.372 1.00 87.24  ? 345 PHE   A N   1 
ATOM   2038 C CA  . PHE   A 1 356 ? 152.769 136.935 158.454 1.00 86.46  ? 345 PHE   A CA  1 
ATOM   2039 C C   . PHE   A 1 356 ? 152.004 135.735 157.910 1.00 94.07  ? 345 PHE   A C   1 
ATOM   2040 O O   . PHE   A 1 356 ? 152.124 134.623 158.438 1.00 100.42 ? 345 PHE   A O   1 
ATOM   2041 C CB  . PHE   A 1 356 ? 151.873 137.777 159.362 1.00 82.97  ? 345 PHE   A CB  1 
ATOM   2042 C CG  . PHE   A 1 356 ? 152.624 138.542 160.415 1.00 81.64  ? 345 PHE   A CG  1 
ATOM   2043 C CD1 . PHE   A 1 356 ? 153.323 137.876 161.407 1.00 84.87  ? 345 PHE   A CD1 1 
ATOM   2044 C CD2 . PHE   A 1 356 ? 152.623 139.926 160.417 1.00 76.66  ? 345 PHE   A CD2 1 
ATOM   2045 C CE1 . PHE   A 1 356 ? 154.014 138.578 162.377 1.00 81.32  ? 345 PHE   A CE1 1 
ATOM   2046 C CE2 . PHE   A 1 356 ? 153.311 140.633 161.385 1.00 72.28  ? 345 PHE   A CE2 1 
ATOM   2047 C CZ  . PHE   A 1 356 ? 154.007 139.958 162.366 1.00 69.00  ? 345 PHE   A CZ  1 
ATOM   2048 N N   . LYS   A 1 357 ? 151.211 135.941 156.855 1.00 93.37  ? 346 LYS   A N   1 
ATOM   2049 C CA  . LYS   A 1 357 ? 150.470 134.833 156.259 1.00 97.38  ? 346 LYS   A CA  1 
ATOM   2050 C C   . LYS   A 1 357 ? 151.413 133.784 155.686 1.00 99.88  ? 346 LYS   A C   1 
ATOM   2051 O O   . LYS   A 1 357 ? 151.180 132.579 155.838 1.00 100.14 ? 346 LYS   A O   1 
ATOM   2052 C CB  . LYS   A 1 357 ? 149.526 135.354 155.175 1.00 93.54  ? 346 LYS   A CB  1 
ATOM   2053 N N   . ARG   A 1 358 ? 152.483 134.223 155.018 1.00 98.01  ? 347 ARG   A N   1 
ATOM   2054 C CA  . ARG   A 1 358 ? 153.454 133.280 154.473 1.00 101.91 ? 347 ARG   A CA  1 
ATOM   2055 C C   . ARG   A 1 358 ? 154.168 132.515 155.581 1.00 105.05 ? 347 ARG   A C   1 
ATOM   2056 O O   . ARG   A 1 358 ? 154.394 131.304 155.462 1.00 108.23 ? 347 ARG   A O   1 
ATOM   2057 C CB  . ARG   A 1 358 ? 154.462 134.017 153.592 1.00 95.90  ? 347 ARG   A CB  1 
ATOM   2058 N N   . CYS   A 1 359 ? 154.536 133.205 156.664 1.00 101.98 ? 348 CYS   A N   1 
ATOM   2059 C CA  . CYS   A 1 359 ? 155.223 132.539 157.767 1.00 102.20 ? 348 CYS   A CA  1 
ATOM   2060 C C   . CYS   A 1 359 ? 154.311 131.541 158.468 1.00 103.54 ? 348 CYS   A C   1 
ATOM   2061 O O   . CYS   A 1 359 ? 154.761 130.466 158.883 1.00 108.09 ? 348 CYS   A O   1 
ATOM   2062 C CB  . CYS   A 1 359 ? 155.750 133.575 158.759 1.00 100.57 ? 348 CYS   A CB  1 
ATOM   2063 S SG  . CYS   A 1 359 ? 157.216 134.467 158.194 1.00 100.96 ? 348 CYS   A SG  1 
ATOM   2064 N N   . PHE   A 1 360 ? 153.026 131.876 158.613 1.00 101.28 ? 349 PHE   A N   1 
ATOM   2065 C CA  . PHE   A 1 360 ? 152.095 130.981 159.290 1.00 103.22 ? 349 PHE   A CA  1 
ATOM   2066 C C   . PHE   A 1 360 ? 151.854 129.698 158.507 1.00 110.59 ? 349 PHE   A C   1 
ATOM   2067 O O   . PHE   A 1 360 ? 151.414 128.703 159.091 1.00 115.52 ? 349 PHE   A O   1 
ATOM   2068 C CB  . PHE   A 1 360 ? 150.767 131.695 159.545 1.00 102.89 ? 349 PHE   A CB  1 
ATOM   2069 C CG  . PHE   A 1 360 ? 150.848 132.771 160.590 1.00 101.78 ? 349 PHE   A CG  1 
ATOM   2070 C CD1 . PHE   A 1 360 ? 151.951 132.868 161.423 1.00 101.45 ? 349 PHE   A CD1 1 
ATOM   2071 C CD2 . PHE   A 1 360 ? 149.822 133.686 160.739 1.00 93.10  ? 349 PHE   A CD2 1 
ATOM   2072 C CE1 . PHE   A 1 360 ? 152.027 133.859 162.384 1.00 97.05  ? 349 PHE   A CE1 1 
ATOM   2073 C CE2 . PHE   A 1 360 ? 149.891 134.679 161.698 1.00 89.16  ? 349 PHE   A CE2 1 
ATOM   2074 C CZ  . PHE   A 1 360 ? 150.995 134.765 162.521 1.00 92.60  ? 349 PHE   A CZ  1 
ATOM   2075 N N   . ARG   A 1 361 ? 152.125 129.699 157.203 1.00 111.72 ? 350 ARG   A N   1 
ATOM   2076 C CA  . ARG   A 1 361 ? 152.001 128.497 156.390 1.00 111.39 ? 350 ARG   A CA  1 
ATOM   2077 C C   . ARG   A 1 361 ? 153.319 127.759 156.216 1.00 112.40 ? 350 ARG   A C   1 
ATOM   2078 O O   . ARG   A 1 361 ? 153.317 126.527 156.126 1.00 112.92 ? 350 ARG   A O   1 
ATOM   2079 C CB  . ARG   A 1 361 ? 151.435 128.845 155.009 1.00 104.32 ? 350 ARG   A CB  1 
ATOM   2080 N N   . GLU   A 1 362 ? 154.441 128.480 156.166 1.00 111.49 ? 351 GLU   A N   1 
ATOM   2081 C CA  . GLU   A 1 362 ? 155.738 127.830 156.013 1.00 114.16 ? 351 GLU   A CA  1 
ATOM   2082 C C   . GLU   A 1 362 ? 156.099 127.024 157.256 1.00 118.02 ? 351 GLU   A C   1 
ATOM   2083 O O   . GLU   A 1 362 ? 156.534 125.871 157.163 1.00 118.55 ? 351 GLU   A O   1 
ATOM   2084 C CB  . GLU   A 1 362 ? 156.813 128.877 155.713 1.00 104.73 ? 351 GLU   A CB  1 
ATOM   2085 N N   . PHE   A 1 363 ? 155.923 127.622 158.437 1.00 116.52 ? 352 PHE   A N   1 
ATOM   2086 C CA  . PHE   A 1 363 ? 156.293 126.946 159.675 1.00 117.51 ? 352 PHE   A CA  1 
ATOM   2087 C C   . PHE   A 1 363 ? 155.297 125.864 160.073 1.00 123.34 ? 352 PHE   A C   1 
ATOM   2088 O O   . PHE   A 1 363 ? 155.701 124.856 160.662 1.00 126.89 ? 352 PHE   A O   1 
ATOM   2089 C CB  . PHE   A 1 363 ? 156.437 127.964 160.807 1.00 115.17 ? 352 PHE   A CB  1 
ATOM   2090 C CG  . PHE   A 1 363 ? 156.720 127.345 162.146 1.00 119.05 ? 352 PHE   A CG  1 
ATOM   2091 C CD1 . PHE   A 1 363 ? 157.834 126.544 162.331 1.00 119.71 ? 352 PHE   A CD1 1 
ATOM   2092 C CD2 . PHE   A 1 363 ? 155.873 127.566 163.219 1.00 122.34 ? 352 PHE   A CD2 1 
ATOM   2093 C CE1 . PHE   A 1 363 ? 158.096 125.971 163.563 1.00 119.08 ? 352 PHE   A CE1 1 
ATOM   2094 C CE2 . PHE   A 1 363 ? 156.131 126.998 164.452 1.00 121.26 ? 352 PHE   A CE2 1 
ATOM   2095 C CZ  . PHE   A 1 363 ? 157.244 126.200 164.624 1.00 118.24 ? 352 PHE   A CZ  1 
ATOM   2096 N N   . CYS   A 1 364 ? 154.012 126.044 159.766 1.00 121.73 ? 353 CYS   A N   1 
ATOM   2097 C CA  . CYS   A 1 364 ? 153.004 125.056 160.130 1.00 123.59 ? 353 CYS   A CA  1 
ATOM   2098 C C   . CYS   A 1 364 ? 153.062 123.806 159.265 1.00 125.50 ? 353 CYS   A C   1 
ATOM   2099 O O   . CYS   A 1 364 ? 152.668 122.727 159.724 1.00 122.52 ? 353 CYS   A O   1 
ATOM   2100 C CB  . CYS   A 1 364 ? 151.604 125.670 160.040 1.00 117.40 ? 353 CYS   A CB  1 
ATOM   2101 N N   . ILE   A 1 365 ? 153.541 123.922 158.031 1.00 125.87 ? 354 ILE   A N   1 
ATOM   2102 C CA  . ILE   A 1 365 ? 153.642 122.775 157.140 1.00 125.15 ? 354 ILE   A CA  1 
ATOM   2103 C C   . ILE   A 1 365 ? 154.839 121.913 157.525 1.00 126.78 ? 354 ILE   A C   1 
ATOM   2104 O O   . ILE   A 1 365 ? 155.942 122.100 157.011 1.00 127.44 ? 354 ILE   A O   1 
ATOM   2105 C CB  . ILE   A 1 365 ? 153.738 123.218 155.670 1.00 120.03 ? 354 ILE   A CB  1 
ATOM   2106 N N   . ARG   B 2 2   ? 137.958 153.804 138.432 1.00 104.64 ? 4   ARG   C N   1 
ATOM   2107 C CA  . ARG   B 2 2   ? 138.466 155.028 137.824 1.00 105.40 ? 4   ARG   C CA  1 
ATOM   2108 C C   . ARG   B 2 2   ? 138.643 154.858 136.319 1.00 110.01 ? 4   ARG   C C   1 
ATOM   2109 O O   . ARG   B 2 2   ? 139.297 153.920 135.864 1.00 110.68 ? 4   ARG   C O   1 
ATOM   2110 C CB  . ARG   B 2 2   ? 139.793 155.435 138.468 1.00 102.30 ? 4   ARG   C CB  1 
ATOM   2111 N N   . GLN   B 2 3   ? 138.056 155.774 135.551 1.00 109.24 ? 5   GLN   C N   1 
ATOM   2112 C CA  . GLN   B 2 3   ? 138.122 155.741 134.096 1.00 103.08 ? 5   GLN   C CA  1 
ATOM   2113 C C   . GLN   B 2 3   ? 138.596 157.092 133.587 1.00 99.02  ? 5   GLN   C C   1 
ATOM   2114 O O   . GLN   B 2 3   ? 138.160 158.135 134.086 1.00 99.76  ? 5   GLN   C O   1 
ATOM   2115 C CB  . GLN   B 2 3   ? 136.760 155.391 133.487 1.00 99.22  ? 5   GLN   C CB  1 
ATOM   2116 N N   . LEU   B 2 4   ? 139.484 157.071 132.596 1.00 96.40  ? 6   LEU   C N   1 
ATOM   2117 C CA  . LEU   B 2 4   ? 140.029 158.290 132.012 1.00 89.18  ? 6   LEU   C CA  1 
ATOM   2118 C C   . LEU   B 2 4   ? 139.333 158.563 130.684 1.00 86.42  ? 6   LEU   C C   1 
ATOM   2119 O O   . LEU   B 2 4   ? 139.400 157.743 129.761 1.00 82.97  ? 6   LEU   C O   1 
ATOM   2120 C CB  . LEU   B 2 4   ? 141.539 158.166 131.816 1.00 82.48  ? 6   LEU   C CB  1 
ATOM   2121 C CG  . LEU   B 2 4   ? 142.400 158.500 133.037 1.00 85.19  ? 6   LEU   C CG  1 
ATOM   2122 C CD1 . LEU   B 2 4   ? 143.867 158.206 132.762 1.00 75.59  ? 6   LEU   C CD1 1 
ATOM   2123 C CD2 . LEU   B 2 4   ? 142.207 159.951 133.453 1.00 85.66  ? 6   LEU   C CD2 1 
ATOM   2124 N N   . VAL   B 2 5   ? 138.672 159.712 130.589 1.00 81.67  ? 7   VAL   C N   1 
ATOM   2125 C CA  . VAL   B 2 5   ? 137.905 160.091 129.408 1.00 72.60  ? 7   VAL   C CA  1 
ATOM   2126 C C   . VAL   B 2 5   ? 138.567 161.305 128.774 1.00 64.53  ? 7   VAL   C C   1 
ATOM   2127 O O   . VAL   B 2 5   ? 138.847 162.298 129.457 1.00 65.03  ? 7   VAL   C O   1 
ATOM   2128 C CB  . VAL   B 2 5   ? 136.439 160.383 129.764 1.00 73.27  ? 7   VAL   C CB  1 
ATOM   2129 C CG1 . VAL   B 2 5   ? 135.656 160.769 128.518 1.00 72.26  ? 7   VAL   C CG1 1 
ATOM   2130 C CG2 . VAL   B 2 5   ? 135.809 159.178 130.445 1.00 78.66  ? 7   VAL   C CG2 1 
ATOM   2131 N N   . GLU   B 2 6   ? 138.818 161.229 127.470 1.00 57.80  ? 8   GLU   C N   1 
ATOM   2132 C CA  . GLU   B 2 6   ? 139.402 162.323 126.711 1.00 51.88  ? 8   GLU   C CA  1 
ATOM   2133 C C   . GLU   B 2 6   ? 138.413 162.797 125.654 1.00 47.33  ? 8   GLU   C C   1 
ATOM   2134 O O   . GLU   B 2 6   ? 137.608 162.015 125.140 1.00 57.62  ? 8   GLU   C O   1 
ATOM   2135 C CB  . GLU   B 2 6   ? 140.709 161.896 126.040 1.00 43.98  ? 8   GLU   C CB  1 
ATOM   2136 C CG  . GLU   B 2 6   ? 141.703 161.233 126.971 1.00 45.93  ? 8   GLU   C CG  1 
ATOM   2137 C CD  . GLU   B 2 6   ? 143.003 160.898 126.274 1.00 41.91  ? 8   GLU   C CD  1 
ATOM   2138 O OE1 . GLU   B 2 6   ? 143.178 161.327 125.116 1.00 43.12  ? 8   GLU   C OE1 1 
ATOM   2139 O OE2 . GLU   B 2 6   ? 143.839 160.189 126.870 1.00 40.68  ? 8   GLU   C OE2 1 
ATOM   2140 N N   . SER   B 2 7   ? 138.477 164.084 125.334 1.00 38.19  ? 9   SER   C N   1 
ATOM   2141 C CA  . SER   B 2 7   ? 137.578 164.672 124.349 1.00 44.91  ? 9   SER   C CA  1 
ATOM   2142 C C   . SER   B 2 7   ? 138.237 165.925 123.783 1.00 48.14  ? 9   SER   C C   1 
ATOM   2143 O O   . SER   B 2 7   ? 139.424 166.181 124.013 1.00 48.10  ? 9   SER   C O   1 
ATOM   2144 C CB  . SER   B 2 7   ? 136.208 164.971 124.967 1.00 48.15  ? 9   SER   C CB  1 
ATOM   2145 N N   . GLY   B 2 8   ? 137.461 166.709 123.037 1.00 51.07  ? 10  GLY   C N   1 
ATOM   2146 C CA  . GLY   B 2 8   ? 137.973 167.925 122.439 1.00 48.72  ? 10  GLY   C CA  1 
ATOM   2147 C C   . GLY   B 2 8   ? 138.757 167.735 121.163 1.00 44.95  ? 10  GLY   C C   1 
ATOM   2148 O O   . GLY   B 2 8   ? 139.293 168.709 120.630 1.00 47.07  ? 10  GLY   C O   1 
ATOM   2149 N N   . GLY   B 2 9   ? 138.840 166.508 120.649 1.00 42.05  ? 11  GLY   C N   1 
ATOM   2150 C CA  . GLY   B 2 9   ? 139.574 166.230 119.429 1.00 41.20  ? 11  GLY   C CA  1 
ATOM   2151 C C   . GLY   B 2 9   ? 138.644 166.205 118.229 1.00 36.38  ? 11  GLY   C C   1 
ATOM   2152 O O   . GLY   B 2 9   ? 137.587 165.570 118.261 1.00 37.50  ? 11  GLY   C O   1 
ATOM   2153 N N   . GLY   B 2 10  ? 139.051 166.904 117.173 1.00 31.72  ? 12  GLY   C N   1 
ATOM   2154 C CA  . GLY   B 2 10  ? 138.250 166.972 115.965 1.00 32.14  ? 12  GLY   C CA  1 
ATOM   2155 C C   . GLY   B 2 10  ? 139.046 167.557 114.822 1.00 35.93  ? 12  GLY   C C   1 
ATOM   2156 O O   . GLY   B 2 10  ? 140.211 167.933 114.970 1.00 35.95  ? 12  GLY   C O   1 
ATOM   2157 N N   . LEU   B 2 11  ? 138.393 167.627 113.664 1.00 38.01  ? 13  LEU   C N   1 
ATOM   2158 C CA  . LEU   B 2 11  ? 139.018 168.182 112.471 1.00 35.07  ? 13  LEU   C CA  1 
ATOM   2159 C C   . LEU   B 2 11  ? 139.052 169.702 112.563 1.00 32.29  ? 13  LEU   C C   1 
ATOM   2160 O O   . LEU   B 2 11  ? 138.014 170.346 112.742 1.00 34.00  ? 13  LEU   C O   1 
ATOM   2161 C CB  . LEU   B 2 11  ? 138.262 167.742 111.218 1.00 36.50  ? 13  LEU   C CB  1 
ATOM   2162 N N   . VAL   B 2 12  ? 140.248 170.273 112.443 1.00 32.02  ? 14  VAL   C N   1 
ATOM   2163 C CA  . VAL   B 2 12  ? 140.461 171.707 112.592 1.00 35.26  ? 14  VAL   C CA  1 
ATOM   2164 C C   . VAL   B 2 12  ? 141.363 172.190 111.466 1.00 29.24  ? 14  VAL   C C   1 
ATOM   2165 O O   . VAL   B 2 12  ? 142.399 171.576 111.189 1.00 30.85  ? 14  VAL   C O   1 
ATOM   2166 C CB  . VAL   B 2 12  ? 141.078 172.051 113.962 1.00 42.59  ? 14  VAL   C CB  1 
ATOM   2167 C CG1 . VAL   B 2 12  ? 141.341 173.540 114.069 1.00 45.98  ? 14  VAL   C CG1 1 
ATOM   2168 C CG2 . VAL   B 2 12  ? 140.160 171.600 115.080 1.00 41.37  ? 14  VAL   C CG2 1 
ATOM   2169 N N   . GLN   B 2 13  ? 140.974 173.290 110.826 1.00 25.42  ? 15  GLN   C N   1 
ATOM   2170 C CA  . GLN   B 2 13  ? 141.805 173.888 109.796 1.00 26.87  ? 15  GLN   C CA  1 
ATOM   2171 C C   . GLN   B 2 13  ? 143.120 174.374 110.406 1.00 35.03  ? 15  GLN   C C   1 
ATOM   2172 O O   . GLN   B 2 13  ? 143.188 174.652 111.605 1.00 39.92  ? 15  GLN   C O   1 
ATOM   2173 C CB  . GLN   B 2 13  ? 141.071 175.051 109.134 1.00 27.18  ? 15  GLN   C CB  1 
ATOM   2174 N N   . PRO   B 2 14  ? 144.187 174.460 109.607 1.00 33.74  ? 16  PRO   C N   1 
ATOM   2175 C CA  . PRO   B 2 14  ? 145.480 174.891 110.155 1.00 32.73  ? 16  PRO   C CA  1 
ATOM   2176 C C   . PRO   B 2 14  ? 145.393 176.279 110.774 1.00 33.55  ? 16  PRO   C C   1 
ATOM   2177 O O   . PRO   B 2 14  ? 144.737 177.178 110.244 1.00 34.49  ? 16  PRO   C O   1 
ATOM   2178 C CB  . PRO   B 2 14  ? 146.409 174.875 108.934 1.00 25.34  ? 16  PRO   C CB  1 
ATOM   2179 C CG  . PRO   B 2 14  ? 145.500 174.869 107.747 1.00 24.46  ? 16  PRO   C CG  1 
ATOM   2180 C CD  . PRO   B 2 14  ? 144.283 174.122 108.178 1.00 29.97  ? 16  PRO   C CD  1 
ATOM   2181 N N   . GLY   B 2 15  ? 146.070 176.446 111.908 1.00 33.38  ? 17  GLY   C N   1 
ATOM   2182 C CA  . GLY   B 2 15  ? 146.008 177.676 112.666 1.00 35.34  ? 17  GLY   C CA  1 
ATOM   2183 C C   . GLY   B 2 15  ? 144.861 177.769 113.648 1.00 37.92  ? 17  GLY   C C   1 
ATOM   2184 O O   . GLY   B 2 15  ? 144.739 178.792 114.335 1.00 40.28  ? 17  GLY   C O   1 
ATOM   2185 N N   . GLY   B 2 16  ? 144.019 176.739 113.743 1.00 40.02  ? 18  GLY   C N   1 
ATOM   2186 C CA  . GLY   B 2 16  ? 142.879 176.778 114.634 1.00 43.35  ? 18  GLY   C CA  1 
ATOM   2187 C C   . GLY   B 2 16  ? 143.243 176.490 116.078 1.00 44.27  ? 18  GLY   C C   1 
ATOM   2188 O O   . GLY   B 2 16  ? 144.408 176.345 116.445 1.00 44.68  ? 18  GLY   C O   1 
ATOM   2189 N N   . SER   B 2 17  ? 142.209 176.410 116.913 1.00 44.90  ? 19  SER   C N   1 
ATOM   2190 C CA  . SER   B 2 17  ? 142.370 176.214 118.348 1.00 47.59  ? 19  SER   C CA  1 
ATOM   2191 C C   . SER   B 2 17  ? 141.511 175.047 118.810 1.00 50.51  ? 19  SER   C C   1 
ATOM   2192 O O   . SER   B 2 17  ? 140.396 174.857 118.313 1.00 53.68  ? 19  SER   C O   1 
ATOM   2193 C CB  . SER   B 2 17  ? 141.999 177.483 119.123 1.00 47.36  ? 19  SER   C CB  1 
ATOM   2194 N N   . LEU   B 2 18  ? 142.032 174.270 119.760 1.00 46.40  ? 20  LEU   C N   1 
ATOM   2195 C CA  . LEU   B 2 18  ? 141.340 173.107 120.303 1.00 44.01  ? 20  LEU   C CA  1 
ATOM   2196 C C   . LEU   B 2 18  ? 141.460 173.100 121.818 1.00 43.12  ? 20  LEU   C C   1 
ATOM   2197 O O   . LEU   B 2 18  ? 142.516 173.438 122.362 1.00 45.04  ? 20  LEU   C O   1 
ATOM   2198 C CB  . LEU   B 2 18  ? 141.907 171.805 119.732 1.00 52.62  ? 20  LEU   C CB  1 
ATOM   2199 C CG  . LEU   B 2 18  ? 141.210 171.264 118.485 1.00 52.39  ? 20  LEU   C CG  1 
ATOM   2200 C CD1 . LEU   B 2 18  ? 141.724 169.878 118.145 1.00 38.11  ? 20  LEU   C CD1 1 
ATOM   2201 C CD2 . LEU   B 2 18  ? 139.699 171.254 118.678 1.00 58.69  ? 20  LEU   C CD2 1 
ATOM   2202 N N   . ARG   B 2 19  ? 140.382 172.714 122.494 1.00 48.02  ? 21  ARG   C N   1 
ATOM   2203 C CA  . ARG   B 2 19  ? 140.363 172.599 123.948 1.00 51.90  ? 21  ARG   C CA  1 
ATOM   2204 C C   . ARG   B 2 19  ? 140.284 171.123 124.321 1.00 54.71  ? 21  ARG   C C   1 
ATOM   2205 O O   . ARG   B 2 19  ? 139.189 170.558 124.411 1.00 58.79  ? 21  ARG   C O   1 
ATOM   2206 C CB  . ARG   B 2 19  ? 139.190 173.378 124.540 1.00 42.71  ? 21  ARG   C CB  1 
ATOM   2207 N N   . LEU   B 2 20  ? 141.438 170.501 124.541 1.00 48.30  ? 22  LEU   C N   1 
ATOM   2208 C CA  . LEU   B 2 20  ? 141.473 169.117 124.986 1.00 44.53  ? 22  LEU   C CA  1 
ATOM   2209 C C   . LEU   B 2 20  ? 140.986 169.018 126.427 1.00 45.31  ? 22  LEU   C C   1 
ATOM   2210 O O   . LEU   B 2 20  ? 140.986 169.995 127.176 1.00 46.33  ? 22  LEU   C O   1 
ATOM   2211 C CB  . LEU   B 2 20  ? 142.882 168.535 124.862 1.00 42.60  ? 22  LEU   C CB  1 
ATOM   2212 C CG  . LEU   B 2 20  ? 143.406 168.304 123.444 1.00 39.53  ? 22  LEU   C CG  1 
ATOM   2213 C CD1 . LEU   B 2 20  ? 144.853 167.847 123.479 1.00 37.16  ? 22  LEU   C CD1 1 
ATOM   2214 C CD2 . LEU   B 2 20  ? 142.542 167.290 122.716 1.00 39.66  ? 22  LEU   C CD2 1 
ATOM   2215 N N   . SER   B 2 21  ? 140.560 167.815 126.806 1.00 48.91  ? 23  SER   C N   1 
ATOM   2216 C CA  . SER   B 2 21  ? 139.970 167.602 128.120 1.00 47.77  ? 23  SER   C CA  1 
ATOM   2217 C C   . SER   B 2 21  ? 140.279 166.192 128.596 1.00 47.66  ? 23  SER   C C   1 
ATOM   2218 O O   . SER   B 2 21  ? 140.331 165.260 127.790 1.00 52.28  ? 23  SER   C O   1 
ATOM   2219 C CB  . SER   B 2 21  ? 138.454 167.826 128.085 1.00 51.30  ? 23  SER   C CB  1 
ATOM   2220 N N   . CYS   B 2 22  ? 140.488 166.047 129.901 1.00 54.10  ? 24  CYS   C N   1 
ATOM   2221 C CA  . CYS   B 2 22  ? 140.697 164.755 130.538 1.00 63.91  ? 24  CYS   C CA  1 
ATOM   2222 C C   . CYS   B 2 22  ? 139.971 164.745 131.875 1.00 75.92  ? 24  CYS   C C   1 
ATOM   2223 O O   . CYS   B 2 22  ? 140.127 165.674 132.675 1.00 76.44  ? 24  CYS   C O   1 
ATOM   2224 C CB  . CYS   B 2 22  ? 142.188 164.472 130.732 1.00 62.61  ? 24  CYS   C CB  1 
ATOM   2225 S SG  . CYS   B 2 22  ? 142.587 162.767 131.162 1.00 69.40  ? 24  CYS   C SG  1 
ATOM   2226 N N   . ALA   B 2 23  ? 139.181 163.702 132.115 1.00 80.13  ? 25  ALA   C N   1 
ATOM   2227 C CA  . ALA   B 2 23  ? 138.376 163.586 133.324 1.00 88.80  ? 25  ALA   C CA  1 
ATOM   2228 C C   . ALA   B 2 23  ? 138.681 162.269 134.021 1.00 90.98  ? 25  ALA   C C   1 
ATOM   2229 O O   . ALA   B 2 23  ? 138.702 161.212 133.381 1.00 87.92  ? 25  ALA   C O   1 
ATOM   2230 C CB  . ALA   B 2 23  ? 136.882 163.681 133.002 1.00 87.17  ? 25  ALA   C CB  1 
ATOM   2231 N N   . ALA   B 2 24  ? 138.915 162.335 135.328 1.00 93.92  ? 26  ALA   C N   1 
ATOM   2232 C CA  . ALA   B 2 24  ? 139.152 161.159 136.154 1.00 100.29 ? 26  ALA   C CA  1 
ATOM   2233 C C   . ALA   B 2 24  ? 138.194 161.173 137.336 1.00 107.58 ? 26  ALA   C C   1 
ATOM   2234 O O   . ALA   B 2 24  ? 138.042 162.200 138.007 1.00 108.02 ? 26  ALA   C O   1 
ATOM   2235 C CB  . ALA   B 2 24  ? 140.602 161.114 136.643 1.00 101.57 ? 26  ALA   C CB  1 
ATOM   2236 N N   . SER   B 2 25  ? 137.551 160.037 137.588 1.00 114.50 ? 27  SER   C N   1 
ATOM   2237 C CA  . SER   B 2 25  ? 136.600 159.923 138.687 1.00 120.37 ? 27  SER   C CA  1 
ATOM   2238 C C   . SER   B 2 25  ? 137.061 158.890 139.711 1.00 119.71 ? 27  SER   C C   1 
ATOM   2239 O O   . SER   B 2 25  ? 137.417 157.766 139.356 1.00 119.69 ? 27  SER   C O   1 
ATOM   2240 C CB  . SER   B 2 25  ? 135.211 159.557 138.159 1.00 121.23 ? 27  SER   C CB  1 
ATOM   2241 N N   . PHE   B 2 29  ? 142.153 158.141 145.019 1.00 78.56  ? 31  PHE   C N   1 
ATOM   2242 C CA  . PHE   B 2 29  ? 141.964 158.844 146.282 1.00 79.87  ? 31  PHE   C CA  1 
ATOM   2243 C C   . PHE   B 2 29  ? 142.337 160.316 146.123 1.00 77.20  ? 31  PHE   C C   1 
ATOM   2244 O O   . PHE   B 2 29  ? 141.582 161.203 146.523 1.00 74.81  ? 31  PHE   C O   1 
ATOM   2245 C CB  . PHE   B 2 29  ? 142.789 158.182 147.392 1.00 72.34  ? 31  PHE   C CB  1 
ATOM   2246 C CG  . PHE   B 2 29  ? 143.413 159.151 148.357 1.00 74.59  ? 31  PHE   C CG  1 
ATOM   2247 C CD1 . PHE   B 2 29  ? 142.661 159.723 149.370 1.00 73.84  ? 31  PHE   C CD1 1 
ATOM   2248 C CD2 . PHE   B 2 29  ? 144.758 159.473 148.266 1.00 72.06  ? 31  PHE   C CD2 1 
ATOM   2249 C CE1 . PHE   B 2 29  ? 143.233 160.609 150.260 1.00 72.53  ? 31  PHE   C CE1 1 
ATOM   2250 C CE2 . PHE   B 2 29  ? 145.335 160.358 149.156 1.00 66.80  ? 31  PHE   C CE2 1 
ATOM   2251 C CZ  . PHE   B 2 29  ? 144.571 160.926 150.153 1.00 64.89  ? 31  PHE   C CZ  1 
ATOM   2252 N N   . ARG   B 2 30  ? 143.504 160.571 145.536 1.00 73.54  ? 32  ARG   C N   1 
ATOM   2253 C CA  . ARG   B 2 30  ? 143.944 161.925 145.243 1.00 77.21  ? 32  ARG   C CA  1 
ATOM   2254 C C   . ARG   B 2 30  ? 144.805 161.907 143.989 1.00 79.15  ? 32  ARG   C C   1 
ATOM   2255 O O   . ARG   B 2 30  ? 145.697 161.067 143.842 1.00 78.44  ? 32  ARG   C O   1 
ATOM   2256 C CB  . ARG   B 2 30  ? 144.724 162.538 146.414 1.00 75.58  ? 32  ARG   C CB  1 
ATOM   2257 C CG  . ARG   B 2 30  ? 145.120 163.993 146.211 1.00 70.51  ? 32  ARG   C CG  1 
ATOM   2258 C CD  . ARG   B 2 30  ? 143.962 164.926 146.532 1.00 74.87  ? 32  ARG   C CD  1 
ATOM   2259 N NE  . ARG   B 2 30  ? 144.374 166.324 146.562 1.00 77.05  ? 32  ARG   C NE  1 
ATOM   2260 C CZ  . ARG   B 2 30  ? 143.536 167.350 146.642 1.00 81.97  ? 32  ARG   C CZ  1 
ATOM   2261 N NH1 . ARG   B 2 30  ? 142.227 167.170 146.702 1.00 84.49  ? 32  ARG   C NH1 1 
ATOM   2262 N NH2 . ARG   B 2 30  ? 144.025 168.587 146.663 1.00 84.32  ? 32  ARG   C NH2 1 
ATOM   2263 N N   . LEU   B 2 31  ? 144.531 162.847 143.090 1.00 81.25  ? 33  LEU   C N   1 
ATOM   2264 C CA  . LEU   B 2 31  ? 145.229 162.959 141.816 1.00 78.71  ? 33  LEU   C CA  1 
ATOM   2265 C C   . LEU   B 2 31  ? 146.334 163.996 141.952 1.00 82.44  ? 33  LEU   C C   1 
ATOM   2266 O O   . LEU   B 2 31  ? 146.053 165.189 142.110 1.00 89.12  ? 33  LEU   C O   1 
ATOM   2267 C CB  . LEU   B 2 31  ? 144.259 163.347 140.701 1.00 78.88  ? 33  LEU   C CB  1 
ATOM   2268 C CG  . LEU   B 2 31  ? 143.375 162.227 140.152 1.00 83.09  ? 33  LEU   C CG  1 
ATOM   2269 C CD1 . LEU   B 2 31  ? 142.070 162.792 139.623 1.00 89.94  ? 33  LEU   C CD1 1 
ATOM   2270 C CD2 . LEU   B 2 31  ? 144.105 161.466 139.058 1.00 78.86  ? 33  LEU   C CD2 1 
ATOM   2271 N N   . TYR   B 2 32  ? 147.585 163.544 141.887 1.00 79.90  ? 34  TYR   C N   1 
ATOM   2272 C CA  . TYR   B 2 32  ? 148.733 164.432 142.031 1.00 82.54  ? 34  TYR   C CA  1 
ATOM   2273 C C   . TYR   B 2 32  ? 149.292 164.900 140.696 1.00 84.82  ? 34  TYR   C C   1 
ATOM   2274 O O   . TYR   B 2 32  ? 149.638 166.077 140.556 1.00 90.32  ? 34  TYR   C O   1 
ATOM   2275 C CB  . TYR   B 2 32  ? 149.852 163.747 142.824 1.00 77.52  ? 34  TYR   C CB  1 
ATOM   2276 C CG  . TYR   B 2 32  ? 149.398 162.964 144.038 1.00 74.22  ? 34  TYR   C CG  1 
ATOM   2277 C CD1 . TYR   B 2 32  ? 149.076 161.617 143.939 1.00 72.87  ? 34  TYR   C CD1 1 
ATOM   2278 C CD2 . TYR   B 2 32  ? 149.307 163.569 145.285 1.00 68.11  ? 34  TYR   C CD2 1 
ATOM   2279 C CE1 . TYR   B 2 32  ? 148.668 160.898 145.045 1.00 68.71  ? 34  TYR   C CE1 1 
ATOM   2280 C CE2 . TYR   B 2 32  ? 148.899 162.856 146.395 1.00 64.49  ? 34  TYR   C CE2 1 
ATOM   2281 C CZ  . TYR   B 2 32  ? 148.581 161.521 146.269 1.00 64.10  ? 34  TYR   C CZ  1 
ATOM   2282 O OH  . TYR   B 2 32  ? 148.174 160.804 147.369 1.00 60.58  ? 34  TYR   C OH  1 
ATOM   2283 N N   . ASP   B 2 33  ? 149.385 164.011 139.710 1.00 77.63  ? 35  ASP   C N   1 
ATOM   2284 C CA  . ASP   B 2 33  ? 149.989 164.343 138.429 1.00 79.08  ? 35  ASP   C CA  1 
ATOM   2285 C C   . ASP   B 2 33  ? 149.034 163.981 137.301 1.00 81.39  ? 35  ASP   C C   1 
ATOM   2286 O O   . ASP   B 2 33  ? 148.198 163.083 137.424 1.00 85.54  ? 35  ASP   C O   1 
ATOM   2287 C CB  . ASP   B 2 33  ? 151.331 163.624 138.234 1.00 81.85  ? 35  ASP   C CB  1 
ATOM   2288 C CG  . ASP   B 2 33  ? 152.485 164.363 138.876 1.00 86.84  ? 35  ASP   C CG  1 
ATOM   2289 O OD1 . ASP   B 2 33  ? 152.690 165.548 138.544 1.00 82.73  ? 35  ASP   C OD1 1 
ATOM   2290 O OD2 . ASP   B 2 33  ? 153.188 163.761 139.713 1.00 92.06  ? 35  ASP   C OD2 1 
ATOM   2291 N N   . MET   B 2 34  ? 149.173 164.704 136.192 1.00 77.80  ? 36  MET   C N   1 
ATOM   2292 C CA  . MET   B 2 34  ? 148.386 164.476 134.989 1.00 65.55  ? 36  MET   C CA  1 
ATOM   2293 C C   . MET   B 2 34  ? 149.201 164.969 133.804 1.00 63.96  ? 36  MET   C C   1 
ATOM   2294 O O   . MET   B 2 34  ? 149.748 166.073 133.848 1.00 69.08  ? 36  MET   C O   1 
ATOM   2295 C CB  . MET   B 2 34  ? 147.038 165.202 135.065 1.00 65.79  ? 36  MET   C CB  1 
ATOM   2296 C CG  . MET   B 2 34  ? 145.841 164.272 135.166 1.00 73.69  ? 36  MET   C CG  1 
ATOM   2297 S SD  . MET   B 2 34  ? 144.265 165.148 135.212 1.00 84.01  ? 36  MET   C SD  1 
ATOM   2298 C CE  . MET   B 2 34  ? 143.563 164.517 136.733 1.00 79.85  ? 36  MET   C CE  1 
ATOM   2299 N N   . GLY   B 2 35  ? 149.291 164.155 132.752 1.00 62.47  ? 37  GLY   C N   1 
ATOM   2300 C CA  . GLY   B 2 35  ? 150.161 164.461 131.642 1.00 59.00  ? 37  GLY   C CA  1 
ATOM   2301 C C   . GLY   B 2 35  ? 149.486 164.217 130.305 1.00 52.34  ? 37  GLY   C C   1 
ATOM   2302 O O   . GLY   B 2 35  ? 148.373 163.699 130.225 1.00 54.75  ? 37  GLY   C O   1 
ATOM   2303 N N   . TRP   B 2 36  ? 150.193 164.612 129.249 1.00 45.83  ? 38  TRP   C N   1 
ATOM   2304 C CA  . TRP   B 2 36  ? 149.741 164.435 127.877 1.00 44.62  ? 38  TRP   C CA  1 
ATOM   2305 C C   . TRP   B 2 36  ? 150.884 163.905 127.023 1.00 44.82  ? 38  TRP   C C   1 
ATOM   2306 O O   . TRP   B 2 36  ? 152.050 164.236 127.257 1.00 49.60  ? 38  TRP   C O   1 
ATOM   2307 C CB  . TRP   B 2 36  ? 149.221 165.749 127.292 1.00 43.05  ? 38  TRP   C CB  1 
ATOM   2308 C CG  . TRP   B 2 36  ? 147.888 166.167 127.824 1.00 43.66  ? 38  TRP   C CG  1 
ATOM   2309 C CD1 . TRP   B 2 36  ? 147.651 167.032 128.850 1.00 44.25  ? 38  TRP   C CD1 1 
ATOM   2310 C CD2 . TRP   B 2 36  ? 146.604 165.753 127.344 1.00 43.01  ? 38  TRP   C CD2 1 
ATOM   2311 N NE1 . TRP   B 2 36  ? 146.299 167.177 129.045 1.00 47.22  ? 38  TRP   C NE1 1 
ATOM   2312 C CE2 . TRP   B 2 36  ? 145.634 166.402 128.132 1.00 45.57  ? 38  TRP   C CE2 1 
ATOM   2313 C CE3 . TRP   B 2 36  ? 146.181 164.895 126.326 1.00 39.43  ? 38  TRP   C CE3 1 
ATOM   2314 C CZ2 . TRP   B 2 36  ? 144.268 166.219 127.935 1.00 44.77  ? 38  TRP   C CZ2 1 
ATOM   2315 C CZ3 . TRP   B 2 36  ? 144.825 164.714 126.133 1.00 40.69  ? 38  TRP   C CZ3 1 
ATOM   2316 C CH2 . TRP   B 2 36  ? 143.885 165.373 126.933 1.00 45.31  ? 38  TRP   C CH2 1 
ATOM   2317 N N   . PHE   B 2 37  ? 150.545 163.079 126.035 1.00 43.82  ? 39  PHE   C N   1 
ATOM   2318 C CA  . PHE   B 2 37  ? 151.520 162.509 125.117 1.00 41.71  ? 39  PHE   C CA  1 
ATOM   2319 C C   . PHE   B 2 37  ? 150.919 162.420 123.721 1.00 38.39  ? 39  PHE   C C   1 
ATOM   2320 O O   . PHE   B 2 37  ? 149.726 162.160 123.552 1.00 35.31  ? 39  PHE   C O   1 
ATOM   2321 C CB  . PHE   B 2 37  ? 151.985 161.117 125.571 1.00 42.53  ? 39  PHE   C CB  1 
ATOM   2322 C CG  . PHE   B 2 37  ? 152.969 161.142 126.705 1.00 40.80  ? 39  PHE   C CG  1 
ATOM   2323 C CD1 . PHE   B 2 37  ? 152.536 161.246 128.015 1.00 46.89  ? 39  PHE   C CD1 1 
ATOM   2324 C CD2 . PHE   B 2 37  ? 154.326 161.054 126.459 1.00 41.62  ? 39  PHE   C CD2 1 
ATOM   2325 C CE1 . PHE   B 2 37  ? 153.439 161.269 129.057 1.00 54.35  ? 39  PHE   C CE1 1 
ATOM   2326 C CE2 . PHE   B 2 37  ? 155.233 161.074 127.497 1.00 46.53  ? 39  PHE   C CE2 1 
ATOM   2327 C CZ  . PHE   B 2 37  ? 154.789 161.182 128.797 1.00 53.60  ? 39  PHE   C CZ  1 
ATOM   2328 N N   . ARG   B 2 38  ? 151.771 162.622 122.717 1.00 34.77  ? 40  ARG   C N   1 
ATOM   2329 C CA  . ARG   B 2 38  ? 151.370 162.600 121.315 1.00 28.46  ? 40  ARG   C CA  1 
ATOM   2330 C C   . ARG   B 2 38  ? 152.102 161.468 120.615 1.00 34.43  ? 40  ARG   C C   1 
ATOM   2331 O O   . ARG   B 2 38  ? 153.230 161.134 120.989 1.00 39.98  ? 40  ARG   C O   1 
ATOM   2332 C CB  . ARG   B 2 38  ? 151.680 163.929 120.623 1.00 19.43  ? 40  ARG   C CB  1 
ATOM   2333 N N   . GLN   B 2 39  ? 151.464 160.881 119.604 1.00 31.62  ? 41  GLN   C N   1 
ATOM   2334 C CA  . GLN   B 2 39  ? 152.010 159.726 118.901 1.00 27.08  ? 41  GLN   C CA  1 
ATOM   2335 C C   . GLN   B 2 39  ? 151.570 159.755 117.445 1.00 23.66  ? 41  GLN   C C   1 
ATOM   2336 O O   . GLN   B 2 39  ? 150.369 159.754 117.155 1.00 23.60  ? 41  GLN   C O   1 
ATOM   2337 C CB  . GLN   B 2 39  ? 151.558 158.431 119.572 1.00 31.04  ? 41  GLN   C CB  1 
ATOM   2338 C CG  . GLN   B 2 39  ? 152.345 157.213 119.160 1.00 32.01  ? 41  GLN   C CG  1 
ATOM   2339 C CD  . GLN   B 2 39  ? 151.620 155.932 119.493 1.00 38.89  ? 41  GLN   C CD  1 
ATOM   2340 O OE1 . GLN   B 2 39  ? 152.240 154.889 119.668 1.00 46.49  ? 41  GLN   C OE1 1 
ATOM   2341 N NE2 . GLN   B 2 39  ? 150.296 156.002 119.572 1.00 38.34  ? 41  GLN   C NE2 1 
ATOM   2342 N N   . ALA   B 2 40  ? 152.535 159.765 116.540 1.00 25.95  ? 42  ALA   C N   1 
ATOM   2343 C CA  . ALA   B 2 40  ? 152.311 159.747 115.105 1.00 22.58  ? 42  ALA   C CA  1 
ATOM   2344 C C   . ALA   B 2 40  ? 152.497 158.341 114.559 1.00 24.96  ? 42  ALA   C C   1 
ATOM   2345 O O   . ALA   B 2 40  ? 153.164 157.503 115.172 1.00 26.42  ? 42  ALA   C O   1 
ATOM   2346 C CB  . ALA   B 2 40  ? 153.270 160.719 114.414 1.00 22.75  ? 42  ALA   C CB  1 
ATOM   2347 N N   . PRO   B 2 41  ? 151.897 158.036 113.402 1.00 24.63  ? 43  PRO   C N   1 
ATOM   2348 C CA  . PRO   B 2 41  ? 152.068 156.689 112.830 1.00 22.43  ? 43  PRO   C CA  1 
ATOM   2349 C C   . PRO   B 2 41  ? 153.516 156.296 112.599 1.00 27.03  ? 43  PRO   C C   1 
ATOM   2350 O O   . PRO   B 2 41  ? 153.882 155.138 112.830 1.00 32.52  ? 43  PRO   C O   1 
ATOM   2351 C CB  . PRO   B 2 41  ? 151.289 156.785 111.512 1.00 14.14  ? 43  PRO   C CB  1 
ATOM   2352 C CG  . PRO   B 2 41  ? 150.220 157.766 111.809 1.00 13.15  ? 43  PRO   C CG  1 
ATOM   2353 C CD  . PRO   B 2 41  ? 150.887 158.812 112.662 1.00 22.13  ? 43  PRO   C CD  1 
ATOM   2354 N N   . GLY   B 2 42  ? 154.356 157.226 112.158 1.00 28.04  ? 44  GLY   C N   1 
ATOM   2355 C CA  . GLY   B 2 42  ? 155.744 156.906 111.895 1.00 32.20  ? 44  GLY   C CA  1 
ATOM   2356 C C   . GLY   B 2 42  ? 156.703 157.458 112.928 1.00 37.47  ? 44  GLY   C C   1 
ATOM   2357 O O   . GLY   B 2 42  ? 157.899 157.602 112.654 1.00 36.37  ? 44  GLY   C O   1 
ATOM   2358 N N   . LYS   B 2 43  ? 156.199 157.780 114.116 1.00 33.72  ? 45  LYS   C N   1 
ATOM   2359 C CA  . LYS   B 2 43  ? 157.018 158.363 115.166 1.00 34.93  ? 45  LYS   C CA  1 
ATOM   2360 C C   . LYS   B 2 43  ? 156.658 157.752 116.512 1.00 38.52  ? 45  LYS   C C   1 
ATOM   2361 O O   . LYS   B 2 43  ? 155.546 157.261 116.722 1.00 40.09  ? 45  LYS   C O   1 
ATOM   2362 C CB  . LYS   B 2 43  ? 156.854 159.889 115.221 1.00 31.14  ? 45  LYS   C CB  1 
ATOM   2363 N N   . GLU   B 2 44  ? 157.627 157.782 117.423 1.00 42.55  ? 46  GLU   C N   1 
ATOM   2364 C CA  . GLU   B 2 44  ? 157.420 157.349 118.793 1.00 44.98  ? 46  GLU   C CA  1 
ATOM   2365 C C   . GLU   B 2 44  ? 156.729 158.452 119.594 1.00 44.66  ? 46  GLU   C C   1 
ATOM   2366 O O   . GLU   B 2 44  ? 156.698 159.620 119.199 1.00 44.70  ? 46  GLU   C O   1 
ATOM   2367 C CB  . GLU   B 2 44  ? 158.756 156.968 119.433 1.00 50.42  ? 46  GLU   C CB  1 
ATOM   2368 C CG  . GLU   B 2 44  ? 158.655 156.075 120.663 1.00 51.79  ? 46  GLU   C CG  1 
ATOM   2369 C CD  . GLU   B 2 44  ? 158.522 154.608 120.310 1.00 68.01  ? 46  GLU   C CD  1 
ATOM   2370 O OE1 . GLU   B 2 44  ? 159.453 154.058 119.686 1.00 72.95  ? 46  GLU   C OE1 1 
ATOM   2371 O OE2 . GLU   B 2 44  ? 157.490 154.003 120.667 1.00 71.69  ? 46  GLU   C OE2 1 
ATOM   2372 N N   . ARG   B 2 45  ? 156.158 158.063 120.732 1.00 42.77  ? 47  ARG   C N   1 
ATOM   2373 C CA  . ARG   B 2 45  ? 155.524 159.024 121.624 1.00 42.72  ? 47  ARG   C CA  1 
ATOM   2374 C C   . ARG   B 2 45  ? 156.525 160.068 122.097 1.00 47.12  ? 47  ARG   C C   1 
ATOM   2375 O O   . ARG   B 2 45  ? 157.655 159.741 122.472 1.00 49.63  ? 47  ARG   C O   1 
ATOM   2376 C CB  . ARG   B 2 45  ? 154.920 158.308 122.828 1.00 38.14  ? 47  ARG   C CB  1 
ATOM   2377 C CG  . ARG   B 2 45  ? 153.414 158.198 122.819 1.00 34.50  ? 47  ARG   C CG  1 
ATOM   2378 C CD  . ARG   B 2 45  ? 152.999 157.101 123.769 1.00 35.72  ? 47  ARG   C CD  1 
ATOM   2379 N NE  . ARG   B 2 45  ? 151.558 156.905 123.827 1.00 33.38  ? 47  ARG   C NE  1 
ATOM   2380 C CZ  . ARG   B 2 45  ? 150.957 155.766 123.522 1.00 39.39  ? 47  ARG   C CZ  1 
ATOM   2381 N NH1 . ARG   B 2 45  ? 151.632 154.746 123.020 1.00 42.67  ? 47  ARG   C NH1 1 
ATOM   2382 N NH2 . ARG   B 2 45  ? 149.648 155.648 123.717 1.00 40.81  ? 47  ARG   C NH2 1 
ATOM   2383 N N   . GLU   B 2 46  ? 156.105 161.329 122.077 1.00 48.86  ? 48  GLU   C N   1 
ATOM   2384 C CA  . GLU   B 2 46  ? 156.911 162.435 122.573 1.00 57.26  ? 48  GLU   C CA  1 
ATOM   2385 C C   . GLU   B 2 46  ? 156.119 163.182 123.633 1.00 55.42  ? 48  GLU   C C   1 
ATOM   2386 O O   . GLU   B 2 46  ? 154.955 163.531 123.409 1.00 53.51  ? 48  GLU   C O   1 
ATOM   2387 C CB  . GLU   B 2 46  ? 157.305 163.386 121.441 1.00 64.28  ? 48  GLU   C CB  1 
ATOM   2388 C CG  . GLU   B 2 46  ? 157.777 164.745 121.920 1.00 70.21  ? 48  GLU   C CG  1 
ATOM   2389 C CD  . GLU   B 2 46  ? 157.924 165.738 120.788 1.00 84.56  ? 48  GLU   C CD  1 
ATOM   2390 O OE1 . GLU   B 2 46  ? 157.870 165.315 119.614 1.00 91.67  ? 48  GLU   C OE1 1 
ATOM   2391 O OE2 . GLU   B 2 46  ? 158.092 166.941 121.074 1.00 81.02  ? 48  GLU   C OE2 1 
ATOM   2392 N N   . GLY   B 2 47  ? 156.744 163.422 124.781 1.00 55.28  ? 49  GLY   C N   1 
ATOM   2393 C CA  . GLY   B 2 47  ? 156.084 164.180 125.828 1.00 56.90  ? 49  GLY   C CA  1 
ATOM   2394 C C   . GLY   B 2 47  ? 155.850 165.618 125.400 1.00 57.21  ? 49  GLY   C C   1 
ATOM   2395 O O   . GLY   B 2 47  ? 156.738 166.283 124.864 1.00 62.96  ? 49  GLY   C O   1 
ATOM   2396 N N   . VAL   B 2 48  ? 154.631 166.102 125.642 1.00 55.67  ? 50  VAL   C N   1 
ATOM   2397 C CA  . VAL   B 2 48  ? 154.235 167.453 125.275 1.00 54.00  ? 50  VAL   C CA  1 
ATOM   2398 C C   . VAL   B 2 48  ? 154.022 168.336 126.497 1.00 53.65  ? 50  VAL   C C   1 
ATOM   2399 O O   . VAL   B 2 48  ? 154.306 169.538 126.455 1.00 54.93  ? 50  VAL   C O   1 
ATOM   2400 C CB  . VAL   B 2 48  ? 152.973 167.444 124.386 1.00 44.19  ? 50  VAL   C CB  1 
ATOM   2401 C CG1 . VAL   B 2 48  ? 153.324 166.987 122.983 1.00 42.00  ? 50  VAL   C CG1 1 
ATOM   2402 C CG2 . VAL   B 2 48  ? 151.901 166.554 124.986 1.00 38.72  ? 50  VAL   C CG2 1 
ATOM   2403 N N   . ALA   B 2 49  ? 153.527 167.768 127.594 1.00 49.68  ? 51  ALA   C N   1 
ATOM   2404 C CA  . ALA   B 2 49  ? 153.246 168.559 128.781 1.00 54.73  ? 51  ALA   C CA  1 
ATOM   2405 C C   . ALA   B 2 49  ? 153.383 167.685 130.018 1.00 57.14  ? 51  ALA   C C   1 
ATOM   2406 O O   . ALA   B 2 49  ? 153.337 166.455 129.936 1.00 56.31  ? 51  ALA   C O   1 
ATOM   2407 C CB  . ALA   B 2 49  ? 151.847 169.181 128.720 1.00 56.00  ? 51  ALA   C CB  1 
ATOM   2408 N N   . SER   B 2 50  ? 153.557 168.342 131.162 1.00 60.73  ? 52  SER   C N   1 
ATOM   2409 C CA  . SER   B 2 50  ? 153.621 167.672 132.452 1.00 63.46  ? 52  SER   C CA  1 
ATOM   2410 C C   . SER   B 2 50  ? 153.319 168.695 133.536 1.00 70.82  ? 52  SER   C C   1 
ATOM   2411 O O   . SER   B 2 50  ? 153.997 169.721 133.633 1.00 73.74  ? 52  SER   C O   1 
ATOM   2412 C CB  . SER   B 2 50  ? 154.993 167.030 132.687 1.00 63.76  ? 52  SER   C CB  1 
ATOM   2413 N N   . ILE   B 2 51  ? 152.306 168.409 134.350 1.00 69.39  ? 53  ILE   C N   1 
ATOM   2414 C CA  . ILE   B 2 51  ? 151.844 169.334 135.378 1.00 75.65  ? 53  ILE   C CA  1 
ATOM   2415 C C   . ILE   B 2 51  ? 151.631 168.564 136.674 1.00 79.01  ? 53  ILE   C C   1 
ATOM   2416 O O   . ILE   B 2 51  ? 151.156 167.423 136.663 1.00 80.25  ? 53  ILE   C O   1 
ATOM   2417 C CB  . ILE   B 2 51  ? 150.556 170.068 134.943 1.00 74.06  ? 53  ILE   C CB  1 
ATOM   2418 C CG1 . ILE   B 2 51  ? 150.118 171.079 136.006 1.00 78.51  ? 53  ILE   C CG1 1 
ATOM   2419 C CG2 . ILE   B 2 51  ? 149.444 169.083 134.655 1.00 68.46  ? 53  ILE   C CG2 1 
ATOM   2420 C CD1 . ILE   B 2 51  ? 149.354 172.262 135.448 1.00 72.91  ? 53  ILE   C CD1 1 
ATOM   2421 N N   . THR   B 2 52  ? 152.005 169.182 137.789 1.00 84.10  ? 54  THR   C N   1 
ATOM   2422 C CA  . THR   B 2 52  ? 151.813 168.592 139.102 1.00 87.84  ? 54  THR   C CA  1 
ATOM   2423 C C   . THR   B 2 52  ? 150.568 169.170 139.771 1.00 89.48  ? 54  THR   C C   1 
ATOM   2424 O O   . THR   B 2 52  ? 149.848 169.995 139.204 1.00 91.41  ? 54  THR   C O   1 
ATOM   2425 C CB  . THR   B 2 52  ? 153.041 168.826 139.981 1.00 92.45  ? 54  THR   C CB  1 
ATOM   2426 O OG1 . THR   B 2 52  ? 153.078 170.198 140.396 1.00 95.97  ? 54  THR   C OG1 1 
ATOM   2427 C CG2 . THR   B 2 52  ? 154.312 168.502 139.212 1.00 94.96  ? 54  THR   C CG2 1 
ATOM   2428 N N   . SER   B 2 53  ? 150.313 168.713 140.999 1.00 87.84  ? 55  SER   C N   1 
ATOM   2429 C CA  . SER   B 2 53  ? 149.210 169.270 141.774 1.00 87.81  ? 55  SER   C CA  1 
ATOM   2430 C C   . SER   B 2 53  ? 149.455 170.733 142.113 1.00 87.32  ? 55  SER   C C   1 
ATOM   2431 O O   . SER   B 2 53  ? 148.506 171.524 142.176 1.00 82.08  ? 55  SER   C O   1 
ATOM   2432 C CB  . SER   B 2 53  ? 148.996 168.452 143.048 1.00 86.32  ? 55  SER   C CB  1 
ATOM   2433 N N   . GLY   B 2 54  ? 150.716 171.110 142.339 1.00 85.86  ? 56  GLY   C N   1 
ATOM   2434 C CA  . GLY   B 2 54  ? 151.026 172.506 142.601 1.00 86.60  ? 56  GLY   C CA  1 
ATOM   2435 C C   . GLY   B 2 54  ? 150.727 173.404 141.417 1.00 92.69  ? 56  GLY   C C   1 
ATOM   2436 O O   . GLY   B 2 54  ? 150.333 174.561 141.586 1.00 97.50  ? 56  GLY   C O   1 
ATOM   2437 N N   . GLY   B 2 55  ? 150.910 172.888 140.205 1.00 88.99  ? 57  GLY   C N   1 
ATOM   2438 C CA  . GLY   B 2 55  ? 150.629 173.634 138.998 1.00 83.61  ? 57  GLY   C CA  1 
ATOM   2439 C C   . GLY   B 2 55  ? 151.821 173.933 138.112 1.00 82.38  ? 57  GLY   C C   1 
ATOM   2440 O O   . GLY   B 2 55  ? 151.641 174.560 137.061 1.00 83.72  ? 57  GLY   C O   1 
ATOM   2441 N N   . SER   B 2 56  ? 153.025 173.516 138.496 1.00 83.68  ? 58  SER   C N   1 
ATOM   2442 C CA  . SER   B 2 56  ? 154.194 173.738 137.657 1.00 85.67  ? 58  SER   C CA  1 
ATOM   2443 C C   . SER   B 2 56  ? 154.082 172.928 136.371 1.00 84.13  ? 58  SER   C C   1 
ATOM   2444 O O   . SER   B 2 56  ? 153.616 171.786 136.377 1.00 84.58  ? 58  SER   C O   1 
ATOM   2445 C CB  . SER   B 2 56  ? 155.469 173.359 138.409 1.00 90.07  ? 58  SER   C CB  1 
ATOM   2446 N N   . THR   B 2 57  ? 154.517 173.524 135.262 1.00 79.32  ? 59  THR   C N   1 
ATOM   2447 C CA  . THR   B 2 57  ? 154.355 172.916 133.949 1.00 72.44  ? 59  THR   C CA  1 
ATOM   2448 C C   . THR   B 2 57  ? 155.709 172.769 133.270 1.00 74.62  ? 59  THR   C C   1 
ATOM   2449 O O   . THR   B 2 57  ? 156.592 173.618 133.414 1.00 78.76  ? 59  THR   C O   1 
ATOM   2450 C CB  . THR   B 2 57  ? 153.427 173.742 133.051 1.00 68.51  ? 59  THR   C CB  1 
ATOM   2451 O OG1 . THR   B 2 57  ? 153.982 175.050 132.865 1.00 68.36  ? 59  THR   C OG1 1 
ATOM   2452 C CG2 . THR   B 2 57  ? 152.053 173.871 133.681 1.00 69.03  ? 59  THR   C CG2 1 
ATOM   2453 N N   . LYS   B 2 58  ? 155.856 171.677 132.523 1.00 71.25  ? 60  LYS   C N   1 
ATOM   2454 C CA  . LYS   B 2 58  ? 157.030 171.436 131.698 1.00 71.74  ? 60  LYS   C CA  1 
ATOM   2455 C C   . LYS   B 2 58  ? 156.566 171.080 130.294 1.00 68.02  ? 60  LYS   C C   1 
ATOM   2456 O O   . LYS   B 2 58  ? 155.595 170.341 130.117 1.00 68.62  ? 60  LYS   C O   1 
ATOM   2457 C CB  . LYS   B 2 58  ? 157.911 170.318 132.273 1.00 70.09  ? 60  LYS   C CB  1 
ATOM   2458 N N   . TYR   B 2 59  ? 157.264 171.615 129.296 1.00 64.78  ? 61  TYR   C N   1 
ATOM   2459 C CA  . TYR   B 2 59  ? 156.826 171.523 127.911 1.00 59.96  ? 61  TYR   C CA  1 
ATOM   2460 C C   . TYR   B 2 59  ? 157.926 170.938 127.040 1.00 65.85  ? 61  TYR   C C   1 
ATOM   2461 O O   . TYR   B 2 59  ? 159.088 170.855 127.446 1.00 73.55  ? 61  TYR   C O   1 
ATOM   2462 C CB  . TYR   B 2 59  ? 156.426 172.898 127.371 1.00 58.34  ? 61  TYR   C CB  1 
ATOM   2463 C CG  . TYR   B 2 59  ? 155.078 173.355 127.860 1.00 56.00  ? 61  TYR   C CG  1 
ATOM   2464 C CD1 . TYR   B 2 59  ? 154.085 172.436 128.162 1.00 54.45  ? 61  TYR   C CD1 1 
ATOM   2465 C CD2 . TYR   B 2 59  ? 154.806 174.702 128.045 1.00 56.55  ? 61  TYR   C CD2 1 
ATOM   2466 C CE1 . TYR   B 2 59  ? 152.851 172.846 128.618 1.00 52.86  ? 61  TYR   C CE1 1 
ATOM   2467 C CE2 . TYR   B 2 59  ? 153.575 175.122 128.504 1.00 55.66  ? 61  TYR   C CE2 1 
ATOM   2468 C CZ  . TYR   B 2 59  ? 152.602 174.189 128.788 1.00 53.59  ? 61  TYR   C CZ  1 
ATOM   2469 O OH  . TYR   B 2 59  ? 151.375 174.599 129.249 1.00 49.73  ? 61  TYR   C OH  1 
ATOM   2470 N N   . ALA   B 2 60  ? 157.540 170.527 125.835 1.00 63.25  ? 62  ALA   C N   1 
ATOM   2471 C CA  . ALA   B 2 60  ? 158.508 170.121 124.830 1.00 64.11  ? 62  ALA   C CA  1 
ATOM   2472 C C   . ALA   B 2 60  ? 159.077 171.346 124.119 1.00 65.47  ? 62  ALA   C C   1 
ATOM   2473 O O   . ALA   B 2 60  ? 158.521 172.446 124.175 1.00 65.33  ? 62  ALA   C O   1 
ATOM   2474 C CB  . ALA   B 2 60  ? 157.869 169.173 123.816 1.00 60.53  ? 62  ALA   C CB  1 
ATOM   2475 N N   . ASP   B 2 61  ? 160.210 171.142 123.445 1.00 64.89  ? 63  ASP   C N   1 
ATOM   2476 C CA  . ASP   B 2 61  ? 160.873 172.248 122.761 1.00 65.65  ? 63  ASP   C CA  1 
ATOM   2477 C C   . ASP   B 2 61  ? 159.989 172.826 121.662 1.00 67.68  ? 63  ASP   C C   1 
ATOM   2478 O O   . ASP   B 2 61  ? 159.807 174.045 121.571 1.00 65.20  ? 63  ASP   C O   1 
ATOM   2479 C CB  . ASP   B 2 61  ? 162.212 171.782 122.189 1.00 68.46  ? 63  ASP   C CB  1 
ATOM   2480 N N   . SER   B 2 62  ? 159.423 171.959 120.818 1.00 71.73  ? 64  SER   C N   1 
ATOM   2481 C CA  . SER   B 2 62  ? 158.544 172.432 119.752 1.00 69.67  ? 64  SER   C CA  1 
ATOM   2482 C C   . SER   B 2 62  ? 157.176 172.821 120.297 1.00 64.23  ? 64  SER   C C   1 
ATOM   2483 O O   . SER   B 2 62  ? 156.488 173.671 119.719 1.00 58.05  ? 64  SER   C O   1 
ATOM   2484 C CB  . SER   B 2 62  ? 158.408 171.360 118.671 1.00 60.50  ? 64  SER   C CB  1 
ATOM   2485 N N   . VAL   B 2 63  ? 156.761 172.202 121.404 1.00 58.40  ? 65  VAL   C N   1 
ATOM   2486 C CA  . VAL   B 2 63  ? 155.455 172.493 121.986 1.00 47.97  ? 65  VAL   C CA  1 
ATOM   2487 C C   . VAL   B 2 63  ? 155.429 173.874 122.627 1.00 53.65  ? 65  VAL   C C   1 
ATOM   2488 O O   . VAL   B 2 63  ? 154.379 174.527 122.663 1.00 53.10  ? 65  VAL   C O   1 
ATOM   2489 C CB  . VAL   B 2 63  ? 155.076 171.401 123.002 1.00 45.92  ? 65  VAL   C CB  1 
ATOM   2490 N N   . LYS   B 2 64  ? 156.566 174.338 123.144 1.00 56.31  ? 66  LYS   C N   1 
ATOM   2491 C CA  . LYS   B 2 64  ? 156.600 175.571 123.921 1.00 50.49  ? 66  LYS   C CA  1 
ATOM   2492 C C   . LYS   B 2 64  ? 156.145 176.764 123.089 1.00 50.81  ? 66  LYS   C C   1 
ATOM   2493 O O   . LYS   B 2 64  ? 156.437 176.861 121.894 1.00 48.94  ? 66  LYS   C O   1 
ATOM   2494 C CB  . LYS   B 2 64  ? 158.012 175.815 124.457 1.00 51.40  ? 66  LYS   C CB  1 
ATOM   2495 N N   . GLY   B 2 65  ? 155.420 177.675 123.735 1.00 49.43  ? 67  GLY   C N   1 
ATOM   2496 C CA  . GLY   B 2 65  ? 154.905 178.861 123.088 1.00 49.94  ? 67  GLY   C CA  1 
ATOM   2497 C C   . GLY   B 2 65  ? 153.546 178.699 122.447 1.00 42.86  ? 67  GLY   C C   1 
ATOM   2498 O O   . GLY   B 2 65  ? 152.959 179.700 122.014 1.00 42.66  ? 67  GLY   C O   1 
ATOM   2499 N N   . ARG   B 2 66  ? 153.024 177.476 122.376 1.00 40.38  ? 68  ARG   C N   1 
ATOM   2500 C CA  . ARG   B 2 66  ? 151.710 177.223 121.793 1.00 39.72  ? 68  ARG   C CA  1 
ATOM   2501 C C   . ARG   B 2 66  ? 150.807 176.348 122.651 1.00 39.30  ? 68  ARG   C C   1 
ATOM   2502 O O   . ARG   B 2 66  ? 149.603 176.299 122.384 1.00 37.07  ? 68  ARG   C O   1 
ATOM   2503 C CB  . ARG   B 2 66  ? 151.851 176.573 120.408 1.00 38.19  ? 68  ARG   C CB  1 
ATOM   2504 C CG  . ARG   B 2 66  ? 152.964 177.148 119.543 1.00 39.79  ? 68  ARG   C CG  1 
ATOM   2505 C CD  . ARG   B 2 66  ? 152.985 176.514 118.161 1.00 38.85  ? 68  ARG   C CD  1 
ATOM   2506 N NE  . ARG   B 2 66  ? 153.558 175.173 118.187 1.00 40.89  ? 68  ARG   C NE  1 
ATOM   2507 C CZ  . ARG   B 2 66  ? 152.925 174.076 117.795 1.00 36.10  ? 68  ARG   C CZ  1 
ATOM   2508 N NH1 . ARG   B 2 66  ? 151.695 174.123 117.313 1.00 33.70  ? 68  ARG   C NH1 1 
ATOM   2509 N NH2 . ARG   B 2 66  ? 153.544 172.903 117.884 1.00 34.43  ? 68  ARG   C NH2 1 
ATOM   2510 N N   . PHE   B 2 67  ? 151.327 175.651 123.655 1.00 41.39  ? 69  PHE   C N   1 
ATOM   2511 C CA  . PHE   B 2 67  ? 150.543 174.734 124.469 1.00 38.37  ? 69  PHE   C CA  1 
ATOM   2512 C C   . PHE   B 2 67  ? 150.407 175.317 125.869 1.00 46.58  ? 69  PHE   C C   1 
ATOM   2513 O O   . PHE   B 2 67  ? 151.389 175.792 126.445 1.00 49.82  ? 69  PHE   C O   1 
ATOM   2514 C CB  . PHE   B 2 67  ? 151.211 173.355 124.560 1.00 36.82  ? 69  PHE   C CB  1 
ATOM   2515 C CG  . PHE   B 2 67  ? 151.222 172.576 123.265 1.00 38.04  ? 69  PHE   C CG  1 
ATOM   2516 C CD1 . PHE   B 2 67  ? 150.845 173.159 122.068 1.00 39.03  ? 69  PHE   C CD1 1 
ATOM   2517 C CD2 . PHE   B 2 67  ? 151.623 171.251 123.254 1.00 41.38  ? 69  PHE   C CD2 1 
ATOM   2518 C CE1 . PHE   B 2 67  ? 150.876 172.441 120.889 1.00 32.72  ? 69  PHE   C CE1 1 
ATOM   2519 C CE2 . PHE   B 2 67  ? 151.647 170.528 122.077 1.00 35.60  ? 69  PHE   C CE2 1 
ATOM   2520 C CZ  . PHE   B 2 67  ? 151.276 171.125 120.895 1.00 27.82  ? 69  PHE   C CZ  1 
ATOM   2521 N N   . THR   B 2 68  ? 149.190 175.296 126.411 1.00 50.75  ? 70  THR   C N   1 
ATOM   2522 C CA  . THR   B 2 68  ? 148.950 175.708 127.788 1.00 50.17  ? 70  THR   C CA  1 
ATOM   2523 C C   . THR   B 2 68  ? 148.143 174.638 128.509 1.00 44.73  ? 70  THR   C C   1 
ATOM   2524 O O   . THR   B 2 68  ? 147.012 174.335 128.119 1.00 43.77  ? 70  THR   C O   1 
ATOM   2525 C CB  . THR   B 2 68  ? 148.212 177.053 127.876 1.00 51.52  ? 70  THR   C CB  1 
ATOM   2526 O OG1 . THR   B 2 68  ? 146.827 176.861 127.571 1.00 54.23  ? 70  THR   C OG1 1 
ATOM   2527 C CG2 . THR   B 2 68  ? 148.814 178.076 126.920 1.00 49.33  ? 70  THR   C CG2 1 
ATOM   2528 N N   . ILE   B 2 69  ? 148.724 174.077 129.568 1.00 43.28  ? 71  ILE   C N   1 
ATOM   2529 C CA  . ILE   B 2 69  ? 148.081 173.032 130.354 1.00 45.86  ? 71  ILE   C CA  1 
ATOM   2530 C C   . ILE   B 2 69  ? 147.883 173.542 131.775 1.00 53.02  ? 71  ILE   C C   1 
ATOM   2531 O O   . ILE   B 2 69  ? 148.819 174.048 132.403 1.00 59.92  ? 71  ILE   C O   1 
ATOM   2532 C CB  . ILE   B 2 69  ? 148.895 171.718 130.342 1.00 46.22  ? 71  ILE   C CB  1 
ATOM   2533 C CG1 . ILE   B 2 69  ? 148.244 170.665 131.237 1.00 55.38  ? 71  ILE   C CG1 1 
ATOM   2534 C CG2 . ILE   B 2 69  ? 150.333 171.952 130.771 1.00 48.12  ? 71  ILE   C CG2 1 
ATOM   2535 C CD1 . ILE   B 2 69  ? 148.889 169.302 131.121 1.00 53.78  ? 71  ILE   C CD1 1 
ATOM   2536 N N   . SER   B 2 70  ? 146.656 173.424 132.274 1.00 48.50  ? 72  SER   C N   1 
ATOM   2537 C CA  . SER   B 2 70  ? 146.339 173.885 133.616 1.00 55.32  ? 72  SER   C CA  1 
ATOM   2538 C C   . SER   B 2 70  ? 145.421 172.872 134.281 1.00 61.49  ? 72  SER   C C   1 
ATOM   2539 O O   . SER   B 2 70  ? 144.649 172.175 133.619 1.00 62.47  ? 72  SER   C O   1 
ATOM   2540 C CB  . SER   B 2 70  ? 145.696 175.275 133.592 1.00 58.92  ? 72  SER   C CB  1 
ATOM   2541 O OG  . SER   B 2 70  ? 144.477 175.255 132.874 1.00 53.71  ? 72  SER   C OG  1 
ATOM   2542 N N   . ARG   B 2 71  ? 145.506 172.807 135.606 1.00 69.49  ? 73  ARG   C N   1 
ATOM   2543 C CA  . ARG   B 2 71  ? 144.787 171.819 136.396 1.00 71.54  ? 73  ARG   C CA  1 
ATOM   2544 C C   . ARG   B 2 71  ? 143.716 172.504 137.229 1.00 79.46  ? 73  ARG   C C   1 
ATOM   2545 O O   . ARG   B 2 71  ? 143.978 173.531 137.863 1.00 76.22  ? 73  ARG   C O   1 
ATOM   2546 C CB  . ARG   B 2 71  ? 145.742 171.048 137.309 1.00 72.54  ? 73  ARG   C CB  1 
ATOM   2547 C CG  . ARG   B 2 71  ? 146.613 170.043 136.588 1.00 67.30  ? 73  ARG   C CG  1 
ATOM   2548 C CD  . ARG   B 2 71  ? 147.137 168.998 137.552 1.00 73.49  ? 73  ARG   C CD  1 
ATOM   2549 N NE  . ARG   B 2 71  ? 146.061 168.414 138.343 1.00 76.35  ? 73  ARG   C NE  1 
ATOM   2550 C CZ  . ARG   B 2 71  ? 146.176 167.306 139.061 1.00 81.21  ? 73  ARG   C CZ  1 
ATOM   2551 N NH1 . ARG   B 2 71  ? 147.312 166.631 139.110 1.00 81.99  ? 73  ARG   C NH1 1 
ATOM   2552 N NH2 . ARG   B 2 71  ? 145.125 166.863 139.744 1.00 87.77  ? 73  ARG   C NH2 1 
ATOM   2553 N N   . ASP   B 2 72  ? 142.513 171.936 137.219 1.00 86.04  ? 74  ASP   C N   1 
ATOM   2554 C CA  . ASP   B 2 72  ? 141.425 172.366 138.093 1.00 95.70  ? 74  ASP   C CA  1 
ATOM   2555 C C   . ASP   B 2 72  ? 141.290 171.310 139.185 1.00 97.69  ? 74  ASP   C C   1 
ATOM   2556 O O   . ASP   B 2 72  ? 140.617 170.293 139.000 1.00 96.03  ? 74  ASP   C O   1 
ATOM   2557 C CB  . ASP   B 2 72  ? 140.129 172.546 137.310 1.00 95.59  ? 74  ASP   C CB  1 
ATOM   2558 C CG  . ASP   B 2 72  ? 139.019 173.150 138.150 1.00 102.31 ? 74  ASP   C CG  1 
ATOM   2559 O OD1 . ASP   B 2 72  ? 139.076 174.366 138.431 1.00 108.23 ? 74  ASP   C OD1 1 
ATOM   2560 O OD2 . ASP   B 2 72  ? 138.088 172.409 138.529 1.00 100.89 ? 74  ASP   C OD2 1 
ATOM   2561 N N   . ASN   B 2 73  ? 141.941 171.556 140.325 1.00 96.59  ? 75  ASN   C N   1 
ATOM   2562 C CA  . ASN   B 2 73  ? 141.980 170.556 141.388 1.00 96.85  ? 75  ASN   C CA  1 
ATOM   2563 C C   . ASN   B 2 73  ? 140.603 170.337 142.001 1.00 101.12 ? 75  ASN   C C   1 
ATOM   2564 O O   . ASN   B 2 73  ? 140.319 169.254 142.528 1.00 104.20 ? 75  ASN   C O   1 
ATOM   2565 C CB  . ASN   B 2 73  ? 142.987 170.968 142.462 1.00 97.41  ? 75  ASN   C CB  1 
ATOM   2566 C CG  . ASN   B 2 73  ? 144.388 171.150 141.910 1.00 92.53  ? 75  ASN   C CG  1 
ATOM   2567 O OD1 . ASN   B 2 73  ? 145.225 170.253 142.006 1.00 90.21  ? 75  ASN   C OD1 1 
ATOM   2568 N ND2 . ASN   B 2 73  ? 144.652 172.319 141.337 1.00 85.61  ? 75  ASN   C ND2 1 
ATOM   2569 N N   . ALA   B 2 74  ? 139.737 171.353 141.952 1.00 102.25 ? 76  ALA   C N   1 
ATOM   2570 C CA  . ALA   B 2 74  ? 138.404 171.216 142.531 1.00 104.44 ? 76  ALA   C CA  1 
ATOM   2571 C C   . ALA   B 2 74  ? 137.602 170.129 141.827 1.00 102.83 ? 76  ALA   C C   1 
ATOM   2572 O O   . ALA   B 2 74  ? 136.952 169.305 142.481 1.00 101.04 ? 76  ALA   C O   1 
ATOM   2573 C CB  . ALA   B 2 74  ? 137.665 172.552 142.471 1.00 105.03 ? 76  ALA   C CB  1 
ATOM   2574 N N   . LYS   B 2 75  ? 137.637 170.107 140.497 1.00 102.15 ? 77  LYS   C N   1 
ATOM   2575 C CA  . LYS   B 2 75  ? 136.945 169.092 139.716 1.00 102.53 ? 77  LYS   C CA  1 
ATOM   2576 C C   . LYS   B 2 75  ? 137.858 167.956 139.277 1.00 101.26 ? 77  LYS   C C   1 
ATOM   2577 O O   . LYS   B 2 75  ? 137.392 167.036 138.598 1.00 99.99  ? 77  LYS   C O   1 
ATOM   2578 C CB  . LYS   B 2 75  ? 136.286 169.728 138.487 1.00 104.00 ? 77  LYS   C CB  1 
ATOM   2579 N N   . ASN   B 2 76  ? 139.140 167.999 139.651 1.00 100.77 ? 78  ASN   C N   1 
ATOM   2580 C CA  . ASN   B 2 76  ? 140.117 166.979 139.264 1.00 100.39 ? 78  ASN   C CA  1 
ATOM   2581 C C   . ASN   B 2 76  ? 140.159 166.802 137.748 1.00 99.84  ? 78  ASN   C C   1 
ATOM   2582 O O   . ASN   B 2 76  ? 140.285 165.688 137.235 1.00 96.60  ? 78  ASN   C O   1 
ATOM   2583 C CB  . ASN   B 2 76  ? 139.833 165.647 139.962 1.00 97.83  ? 78  ASN   C CB  1 
ATOM   2584 N N   . THR   B 2 77  ? 140.051 167.914 137.024 1.00 97.98  ? 79  THR   C N   1 
ATOM   2585 C CA  . THR   B 2 77  ? 140.000 167.912 135.569 1.00 93.85  ? 79  THR   C CA  1 
ATOM   2586 C C   . THR   B 2 77  ? 141.135 168.763 135.019 1.00 86.43  ? 79  THR   C C   1 
ATOM   2587 O O   . THR   B 2 77  ? 141.349 169.891 135.477 1.00 85.30  ? 79  THR   C O   1 
ATOM   2588 C CB  . THR   B 2 77  ? 138.653 168.443 135.067 1.00 94.63  ? 79  THR   C CB  1 
ATOM   2589 O OG1 . THR   B 2 77  ? 137.594 167.630 135.587 1.00 94.70  ? 79  THR   C OG1 1 
ATOM   2590 C CG2 . THR   B 2 77  ? 138.600 168.427 133.546 1.00 82.80  ? 79  THR   C CG2 1 
ATOM   2591 N N   . VAL   B 2 78  ? 141.857 168.221 134.044 1.00 76.15  ? 80  VAL   C N   1 
ATOM   2592 C CA  . VAL   B 2 78  ? 142.889 168.960 133.335 1.00 67.65  ? 80  VAL   C CA  1 
ATOM   2593 C C   . VAL   B 2 78  ? 142.378 169.247 131.929 1.00 61.19  ? 80  VAL   C C   1 
ATOM   2594 O O   . VAL   B 2 78  ? 141.534 168.530 131.384 1.00 66.58  ? 80  VAL   C O   1 
ATOM   2595 C CB  . VAL   B 2 78  ? 144.234 168.198 133.294 1.00 65.16  ? 80  VAL   C CB  1 
ATOM   2596 C CG1 . VAL   B 2 78  ? 144.182 167.065 132.286 1.00 67.30  ? 80  VAL   C CG1 1 
ATOM   2597 C CG2 . VAL   B 2 78  ? 145.384 169.139 132.982 1.00 62.15  ? 80  VAL   C CG2 1 
ATOM   2598 N N   . TYR   B 2 79  ? 142.880 170.332 131.347 1.00 53.05  ? 81  TYR   C N   1 
ATOM   2599 C CA  . TYR   B 2 79  ? 142.572 170.656 129.965 1.00 51.92  ? 81  TYR   C CA  1 
ATOM   2600 C C   . TYR   B 2 79  ? 143.798 171.280 129.318 1.00 51.74  ? 81  TYR   C C   1 
ATOM   2601 O O   . TYR   B 2 79  ? 144.611 171.933 129.976 1.00 55.66  ? 81  TYR   C O   1 
ATOM   2602 C CB  . TYR   B 2 79  ? 141.362 171.596 129.841 1.00 51.52  ? 81  TYR   C CB  1 
ATOM   2603 C CG  . TYR   B 2 79  ? 141.459 172.878 130.633 1.00 54.89  ? 81  TYR   C CG  1 
ATOM   2604 C CD1 . TYR   B 2 79  ? 141.148 172.910 131.987 1.00 58.95  ? 81  TYR   C CD1 1 
ATOM   2605 C CD2 . TYR   B 2 79  ? 141.848 174.063 130.022 1.00 55.79  ? 81  TYR   C CD2 1 
ATOM   2606 C CE1 . TYR   B 2 79  ? 141.229 174.084 132.710 1.00 57.97  ? 81  TYR   C CE1 1 
ATOM   2607 C CE2 . TYR   B 2 79  ? 141.932 175.241 130.737 1.00 64.57  ? 81  TYR   C CE2 1 
ATOM   2608 C CZ  . TYR   B 2 79  ? 141.620 175.246 132.080 1.00 62.11  ? 81  TYR   C CZ  1 
ATOM   2609 O OH  . TYR   B 2 79  ? 141.704 176.416 132.797 1.00 61.83  ? 81  TYR   C OH  1 
ATOM   2610 N N   . LEU   B 2 80  ? 143.920 171.066 128.012 1.00 48.89  ? 82  LEU   C N   1 
ATOM   2611 C CA  . LEU   B 2 80  ? 145.041 171.572 127.236 1.00 45.13  ? 82  LEU   C CA  1 
ATOM   2612 C C   . LEU   B 2 80  ? 144.505 172.463 126.128 1.00 46.97  ? 82  LEU   C C   1 
ATOM   2613 O O   . LEU   B 2 80  ? 143.757 172.000 125.262 1.00 48.35  ? 82  LEU   C O   1 
ATOM   2614 C CB  . LEU   B 2 80  ? 145.869 170.422 126.651 1.00 34.98  ? 82  LEU   C CB  1 
ATOM   2615 C CG  . LEU   B 2 80  ? 147.147 170.785 125.896 1.00 33.84  ? 82  LEU   C CG  1 
ATOM   2616 C CD1 . LEU   B 2 80  ? 148.115 171.503 126.808 1.00 43.44  ? 82  LEU   C CD1 1 
ATOM   2617 C CD2 . LEU   B 2 80  ? 147.790 169.540 125.319 1.00 37.15  ? 82  LEU   C CD2 1 
ATOM   2618 N N   . GLN   B 2 81  ? 144.881 173.738 126.160 1.00 44.64  ? 83  GLN   C N   1 
ATOM   2619 C CA  . GLN   B 2 81  ? 144.498 174.694 125.131 1.00 41.96  ? 83  GLN   C CA  1 
ATOM   2620 C C   . GLN   B 2 81  ? 145.484 174.577 123.979 1.00 40.48  ? 83  GLN   C C   1 
ATOM   2621 O O   . GLN   B 2 81  ? 146.698 174.693 124.180 1.00 40.11  ? 83  GLN   C O   1 
ATOM   2622 C CB  . GLN   B 2 81  ? 144.474 176.118 125.682 1.00 48.79  ? 83  GLN   C CB  1 
ATOM   2623 C CG  . GLN   B 2 81  ? 143.082 176.697 125.857 1.00 53.70  ? 83  GLN   C CG  1 
ATOM   2624 C CD  . GLN   B 2 81  ? 142.248 176.597 124.596 1.00 52.25  ? 83  GLN   C CD  1 
ATOM   2625 O OE1 . GLN   B 2 81  ? 141.312 175.804 124.519 1.00 46.79  ? 83  GLN   C OE1 1 
ATOM   2626 N NE2 . GLN   B 2 81  ? 142.587 177.405 123.598 1.00 50.81  ? 83  GLN   C NE2 1 
ATOM   2627 N N   . MET   B 2 82  ? 144.962 174.350 122.779 1.00 41.32  ? 84  MET   C N   1 
ATOM   2628 C CA  . MET   B 2 82  ? 145.778 174.088 121.604 1.00 38.05  ? 84  MET   C CA  1 
ATOM   2629 C C   . MET   B 2 82  ? 145.787 175.340 120.739 1.00 37.60  ? 84  MET   C C   1 
ATOM   2630 O O   . MET   B 2 82  ? 144.727 175.805 120.313 1.00 37.61  ? 84  MET   C O   1 
ATOM   2631 C CB  . MET   B 2 82  ? 145.211 172.908 120.817 1.00 39.03  ? 84  MET   C CB  1 
ATOM   2632 C CG  . MET   B 2 82  ? 145.932 171.596 121.037 1.00 34.52  ? 84  MET   C CG  1 
ATOM   2633 S SD  . MET   B 2 82  ? 147.687 171.614 120.688 1.00 30.14  ? 84  MET   C SD  1 
ATOM   2634 C CE  . MET   B 2 82  ? 148.064 169.895 121.001 1.00 23.08  ? 84  MET   C CE  1 
ATOM   2635 N N   . ASN   B 2 83  ? 146.972 175.885 120.481 1.00 35.69  ? 85  ASN   C N   1 
ATOM   2636 C CA  . ASN   B 2 83  ? 147.088 177.135 119.745 1.00 34.94  ? 85  ASN   C CA  1 
ATOM   2637 C C   . ASN   B 2 83  ? 148.117 176.998 118.632 1.00 33.54  ? 85  ASN   C C   1 
ATOM   2638 O O   . ASN   B 2 83  ? 149.085 176.242 118.742 1.00 33.27  ? 85  ASN   C O   1 
ATOM   2639 C CB  . ASN   B 2 83  ? 147.477 178.301 120.665 1.00 41.60  ? 85  ASN   C CB  1 
ATOM   2640 C CG  . ASN   B 2 83  ? 146.844 178.202 122.038 1.00 46.03  ? 85  ASN   C CG  1 
ATOM   2641 O OD1 . ASN   B 2 83  ? 147.539 178.054 123.042 1.00 44.80  ? 85  ASN   C OD1 1 
ATOM   2642 N ND2 . ASN   B 2 83  ? 145.521 178.299 122.092 1.00 47.63  ? 85  ASN   C ND2 1 
ATOM   2643 N N   . SER   B 2 84  ? 147.892 177.760 117.557 1.00 32.74  ? 86  SER   C N   1 
ATOM   2644 C CA  . SER   B 2 84  ? 148.791 177.795 116.401 1.00 31.37  ? 86  SER   C CA  1 
ATOM   2645 C C   . SER   B 2 84  ? 149.060 176.393 115.863 1.00 37.22  ? 86  SER   C C   1 
ATOM   2646 O O   . SER   B 2 84  ? 150.199 176.031 115.561 1.00 43.48  ? 86  SER   C O   1 
ATOM   2647 C CB  . SER   B 2 84  ? 150.102 178.508 116.739 1.00 28.11  ? 86  SER   C CB  1 
ATOM   2648 N N   . LEU   B 2 85  ? 148.002 175.593 115.753 1.00 35.18  ? 87  LEU   C N   1 
ATOM   2649 C CA  . LEU   B 2 85  ? 148.150 174.215 115.306 1.00 28.20  ? 87  LEU   C CA  1 
ATOM   2650 C C   . LEU   B 2 85  ? 148.595 174.158 113.851 1.00 27.79  ? 87  LEU   C C   1 
ATOM   2651 O O   . LEU   B 2 85  ? 148.119 174.924 113.009 1.00 31.72  ? 87  LEU   C O   1 
ATOM   2652 C CB  . LEU   B 2 85  ? 146.836 173.460 115.491 1.00 26.97  ? 87  LEU   C CB  1 
ATOM   2653 C CG  . LEU   B 2 85  ? 146.618 172.908 116.897 1.00 26.66  ? 87  LEU   C CG  1 
ATOM   2654 C CD1 . LEU   B 2 85  ? 145.183 172.443 117.087 1.00 32.59  ? 87  LEU   C CD1 1 
ATOM   2655 C CD2 . LEU   B 2 85  ? 147.593 171.774 117.150 1.00 23.95  ? 87  LEU   C CD2 1 
ATOM   2656 N N   . GLU   B 2 86  ? 149.507 173.242 113.565 1.00 23.80  ? 88  GLU   C N   1 
ATOM   2657 C CA  . GLU   B 2 86  ? 150.067 173.019 112.243 1.00 24.40  ? 88  GLU   C CA  1 
ATOM   2658 C C   . GLU   B 2 86  ? 149.810 171.578 111.840 1.00 22.32  ? 88  GLU   C C   1 
ATOM   2659 O O   . GLU   B 2 86  ? 149.576 170.719 112.697 1.00 24.65  ? 88  GLU   C O   1 
ATOM   2660 C CB  . GLU   B 2 86  ? 151.576 173.311 112.228 1.00 24.37  ? 88  GLU   C CB  1 
ATOM   2661 N N   . PRO   B 2 87  ? 149.834 171.277 110.538 1.00 19.73  ? 89  PRO   C N   1 
ATOM   2662 C CA  . PRO   B 2 87  ? 149.626 169.885 110.106 1.00 19.32  ? 89  PRO   C CA  1 
ATOM   2663 C C   . PRO   B 2 87  ? 150.617 168.904 110.708 1.00 22.66  ? 89  PRO   C C   1 
ATOM   2664 O O   . PRO   B 2 87  ? 150.269 167.729 110.882 1.00 23.73  ? 89  PRO   C O   1 
ATOM   2665 C CB  . PRO   B 2 87  ? 149.773 169.967 108.581 1.00 19.51  ? 89  PRO   C CB  1 
ATOM   2666 C CG  . PRO   B 2 87  ? 149.407 171.368 108.251 1.00 20.62  ? 89  PRO   C CG  1 
ATOM   2667 C CD  . PRO   B 2 87  ? 149.905 172.202 109.393 1.00 21.78  ? 89  PRO   C CD  1 
ATOM   2668 N N   . GLU   B 2 88  ? 151.835 169.341 111.035 1.00 21.34  ? 90  GLU   C N   1 
ATOM   2669 C CA  . GLU   B 2 88  ? 152.797 168.451 111.676 1.00 20.83  ? 90  GLU   C CA  1 
ATOM   2670 C C   . GLU   B 2 88  ? 152.338 168.003 113.057 1.00 21.25  ? 90  GLU   C C   1 
ATOM   2671 O O   . GLU   B 2 88  ? 152.861 167.014 113.580 1.00 20.08  ? 90  GLU   C O   1 
ATOM   2672 C CB  . GLU   B 2 88  ? 154.161 169.135 111.778 1.00 19.44  ? 90  GLU   C CB  1 
ATOM   2673 N N   . ASP   B 2 89  ? 151.379 168.704 113.657 1.00 22.54  ? 91  ASP   C N   1 
ATOM   2674 C CA  . ASP   B 2 89  ? 150.821 168.327 114.948 1.00 20.30  ? 91  ASP   C CA  1 
ATOM   2675 C C   . ASP   B 2 89  ? 149.626 167.393 114.822 1.00 19.20  ? 91  ASP   C C   1 
ATOM   2676 O O   . ASP   B 2 89  ? 148.777 167.369 115.719 1.00 18.77  ? 91  ASP   C O   1 
ATOM   2677 C CB  . ASP   B 2 89  ? 150.424 169.575 115.740 1.00 22.01  ? 91  ASP   C CB  1 
ATOM   2678 C CG  . ASP   B 2 89  ? 151.621 170.389 116.183 1.00 28.18  ? 91  ASP   C CG  1 
ATOM   2679 O OD1 . ASP   B 2 89  ? 152.620 169.783 116.626 1.00 26.09  ? 91  ASP   C OD1 1 
ATOM   2680 O OD2 . ASP   B 2 89  ? 151.565 171.633 116.091 1.00 30.84  ? 91  ASP   C OD2 1 
ATOM   2681 N N   . THR   B 2 90  ? 149.532 166.640 113.730 1.00 18.83  ? 92  THR   C N   1 
ATOM   2682 C CA  . THR   B 2 90  ? 148.458 165.668 113.565 1.00 17.12  ? 92  THR   C CA  1 
ATOM   2683 C C   . THR   B 2 90  ? 148.872 164.332 114.171 1.00 17.33  ? 92  THR   C C   1 
ATOM   2684 O O   . THR   B 2 90  ? 149.819 163.696 113.697 1.00 20.17  ? 92  THR   C O   1 
ATOM   2685 C CB  . THR   B 2 90  ? 148.119 165.500 112.088 1.00 15.87  ? 92  THR   C CB  1 
ATOM   2686 O OG1 . THR   B 2 90  ? 147.588 166.727 111.571 1.00 19.35  ? 92  THR   C OG1 1 
ATOM   2687 C CG2 . THR   B 2 90  ? 147.108 164.384 111.901 1.00 14.85  ? 92  THR   C CG2 1 
ATOM   2688 N N   . ALA   B 2 91  ? 148.154 163.903 115.206 1.00 14.46  ? 93  ALA   C N   1 
ATOM   2689 C CA  . ALA   B 2 91  ? 148.486 162.685 115.933 1.00 12.88  ? 93  ALA   C CA  1 
ATOM   2690 C C   . ALA   B 2 91  ? 147.324 162.347 116.854 1.00 11.67  ? 93  ALA   C C   1 
ATOM   2691 O O   . ALA   B 2 91  ? 146.278 163.002 116.833 1.00 10.17  ? 93  ALA   C O   1 
ATOM   2692 C CB  . ALA   B 2 91  ? 149.785 162.841 116.728 1.00 14.14  ? 93  ALA   C CB  1 
ATOM   2693 N N   . VAL   B 2 92  ? 147.517 161.306 117.657 1.00 14.27  ? 94  VAL   C N   1 
ATOM   2694 C CA  . VAL   B 2 92  ? 146.567 160.918 118.692 1.00 17.26  ? 94  VAL   C CA  1 
ATOM   2695 C C   . VAL   B 2 92  ? 147.193 161.314 120.024 1.00 28.85  ? 94  VAL   C C   1 
ATOM   2696 O O   . VAL   B 2 92  ? 148.238 160.789 120.416 1.00 30.90  ? 94  VAL   C O   1 
ATOM   2697 C CB  . VAL   B 2 92  ? 146.236 159.426 118.642 1.00 15.85  ? 94  VAL   C CB  1 
ATOM   2698 C CG1 . VAL   B 2 92  ? 145.631 158.980 119.956 1.00 29.37  ? 94  VAL   C CG1 1 
ATOM   2699 C CG2 . VAL   B 2 92  ? 145.279 159.138 117.511 1.00 19.30  ? 94  VAL   C CG2 1 
ATOM   2700 N N   . TYR   B 2 93  ? 146.554 162.247 120.724 1.00 30.52  ? 95  TYR   C N   1 
ATOM   2701 C CA  . TYR   B 2 93  ? 147.086 162.748 121.983 1.00 26.45  ? 95  TYR   C CA  1 
ATOM   2702 C C   . TYR   B 2 93  ? 146.500 161.942 123.135 1.00 34.14  ? 95  TYR   C C   1 
ATOM   2703 O O   . TYR   B 2 93  ? 145.290 161.692 123.174 1.00 38.60  ? 95  TYR   C O   1 
ATOM   2704 C CB  . TYR   B 2 93  ? 146.781 164.236 122.134 1.00 24.22  ? 95  TYR   C CB  1 
ATOM   2705 C CG  . TYR   B 2 93  ? 147.547 165.106 121.161 1.00 19.72  ? 95  TYR   C CG  1 
ATOM   2706 C CD1 . TYR   B 2 93  ? 147.088 165.306 119.869 1.00 17.91  ? 95  TYR   C CD1 1 
ATOM   2707 C CD2 . TYR   B 2 93  ? 148.735 165.718 121.533 1.00 25.01  ? 95  TYR   C CD2 1 
ATOM   2708 C CE1 . TYR   B 2 93  ? 147.784 166.097 118.978 1.00 17.61  ? 95  TYR   C CE1 1 
ATOM   2709 C CE2 . TYR   B 2 93  ? 149.439 166.511 120.646 1.00 22.47  ? 95  TYR   C CE2 1 
ATOM   2710 C CZ  . TYR   B 2 93  ? 148.960 166.694 119.371 1.00 17.00  ? 95  TYR   C CZ  1 
ATOM   2711 O OH  . TYR   B 2 93  ? 149.658 167.482 118.486 1.00 17.64  ? 95  TYR   C OH  1 
ATOM   2712 N N   . TYR   B 2 94  ? 147.357 161.530 124.065 1.00 36.59  ? 96  TYR   C N   1 
ATOM   2713 C CA  . TYR   B 2 94  ? 146.970 160.654 125.162 1.00 42.49  ? 96  TYR   C CA  1 
ATOM   2714 C C   . TYR   B 2 94  ? 147.030 161.405 126.484 1.00 42.28  ? 96  TYR   C C   1 
ATOM   2715 O O   . TYR   B 2 94  ? 147.894 162.264 126.680 1.00 44.53  ? 96  TYR   C O   1 
ATOM   2716 C CB  . TYR   B 2 94  ? 147.884 159.428 125.220 1.00 45.99  ? 96  TYR   C CB  1 
ATOM   2717 C CG  . TYR   B 2 94  ? 147.731 158.496 124.040 1.00 39.08  ? 96  TYR   C CG  1 
ATOM   2718 C CD1 . TYR   B 2 94  ? 146.794 157.472 124.056 1.00 36.56  ? 96  TYR   C CD1 1 
ATOM   2719 C CD2 . TYR   B 2 94  ? 148.519 158.643 122.909 1.00 34.83  ? 96  TYR   C CD2 1 
ATOM   2720 C CE1 . TYR   B 2 94  ? 146.647 156.622 122.984 1.00 34.18  ? 96  TYR   C CE1 1 
ATOM   2721 C CE2 . TYR   B 2 94  ? 148.376 157.799 121.828 1.00 38.60  ? 96  TYR   C CE2 1 
ATOM   2722 C CZ  . TYR   B 2 94  ? 147.440 156.789 121.872 1.00 39.25  ? 96  TYR   C CZ  1 
ATOM   2723 O OH  . TYR   B 2 94  ? 147.298 155.942 120.797 1.00 43.99  ? 96  TYR   C OH  1 
ATOM   2724 N N   . CYS   B 2 95  ? 146.105 161.084 127.385 1.00 47.09  ? 97  CYS   C N   1 
ATOM   2725 C CA  . CYS   B 2 95  ? 146.121 161.637 128.731 1.00 53.69  ? 97  CYS   C CA  1 
ATOM   2726 C C   . CYS   B 2 95  ? 146.555 160.577 129.735 1.00 56.35  ? 97  CYS   C C   1 
ATOM   2727 O O   . CYS   B 2 95  ? 145.958 159.503 129.833 1.00 63.95  ? 97  CYS   C O   1 
ATOM   2728 C CB  . CYS   B 2 95  ? 144.745 162.180 129.118 1.00 57.02  ? 97  CYS   C CB  1 
ATOM   2729 S SG  . CYS   B 2 95  ? 144.591 162.641 130.858 1.00 58.61  ? 97  CYS   C SG  1 
ATOM   2730 N N   . ASN   B 2 96  ? 147.599 160.898 130.494 1.00 53.53  ? 98  ASN   C N   1 
ATOM   2731 C CA  . ASN   B 2 96  ? 148.143 159.972 131.477 1.00 60.93  ? 98  ASN   C CA  1 
ATOM   2732 C C   . ASN   B 2 96  ? 148.052 160.615 132.850 1.00 69.81  ? 98  ASN   C C   1 
ATOM   2733 O O   . ASN   B 2 96  ? 148.463 161.766 133.027 1.00 74.39  ? 98  ASN   C O   1 
ATOM   2734 C CB  . ASN   B 2 96  ? 149.594 159.605 131.152 1.00 55.91  ? 98  ASN   C CB  1 
ATOM   2735 N N   . ALA   B 2 97  ? 147.513 159.873 133.814 1.00 67.02  ? 99  ALA   C N   1 
ATOM   2736 C CA  . ALA   B 2 97  ? 147.319 160.377 135.164 1.00 67.51  ? 99  ALA   C CA  1 
ATOM   2737 C C   . ALA   B 2 97  ? 147.882 159.382 136.165 1.00 73.88  ? 99  ALA   C C   1 
ATOM   2738 O O   . ALA   B 2 97  ? 147.744 158.168 135.992 1.00 78.70  ? 99  ALA   C O   1 
ATOM   2739 C CB  . ALA   B 2 97  ? 145.835 160.631 135.458 1.00 70.83  ? 99  ALA   C CB  1 
ATOM   2740 N N   . GLU   B 2 98  ? 148.520 159.904 137.208 1.00 76.35  ? 100 GLU   C N   1 
ATOM   2741 C CA  . GLU   B 2 98  ? 149.033 159.103 138.310 1.00 74.21  ? 100 GLU   C CA  1 
ATOM   2742 C C   . GLU   B 2 98  ? 148.247 159.440 139.567 1.00 74.20  ? 100 GLU   C C   1 
ATOM   2743 O O   . GLU   B 2 98  ? 148.114 160.615 139.923 1.00 76.56  ? 100 GLU   C O   1 
ATOM   2744 C CB  . GLU   B 2 98  ? 150.526 159.357 138.530 1.00 71.88  ? 100 GLU   C CB  1 
ATOM   2745 N N   . TYR   B 2 99  ? 147.728 158.412 140.235 1.00 77.18  ? 101 TYR   C N   1 
ATOM   2746 C CA  . TYR   B 2 99  ? 146.923 158.624 141.427 1.00 77.20  ? 101 TYR   C CA  1 
ATOM   2747 C C   . TYR   B 2 99  ? 147.092 157.442 142.367 1.00 66.99  ? 101 TYR   C C   1 
ATOM   2748 O O   . TYR   B 2 99  ? 147.919 156.555 142.145 1.00 67.20  ? 101 TYR   C O   1 
ATOM   2749 C CB  . TYR   B 2 99  ? 145.441 158.829 141.082 1.00 81.09  ? 101 TYR   C CB  1 
ATOM   2750 C CG  . TYR   B 2 99  ? 144.723 157.579 140.621 1.00 79.92  ? 101 TYR   C CG  1 
ATOM   2751 C CD1 . TYR   B 2 99  ? 144.910 157.077 139.340 1.00 73.90  ? 101 TYR   C CD1 1 
ATOM   2752 C CD2 . TYR   B 2 99  ? 143.846 156.909 141.465 1.00 79.48  ? 101 TYR   C CD2 1 
ATOM   2753 C CE1 . TYR   B 2 99  ? 144.252 155.939 138.916 1.00 77.05  ? 101 TYR   C CE1 1 
ATOM   2754 C CE2 . TYR   B 2 99  ? 143.185 155.770 141.050 1.00 78.15  ? 101 TYR   C CE2 1 
ATOM   2755 C CZ  . TYR   B 2 99  ? 143.391 155.289 139.776 1.00 83.36  ? 101 TYR   C CZ  1 
ATOM   2756 O OH  . TYR   B 2 99  ? 142.732 154.155 139.361 1.00 87.89  ? 101 TYR   C OH  1 
ATOM   2757 N N   . ARG   B 2 100 ? 146.296 157.450 143.431 1.00 61.54  ? 102 ARG   C N   1 
ATOM   2758 C CA  . ARG   B 2 100 ? 146.312 156.407 144.444 1.00 64.52  ? 102 ARG   C CA  1 
ATOM   2759 C C   . ARG   B 2 100 ? 144.905 155.848 144.584 1.00 68.86  ? 102 ARG   C C   1 
ATOM   2760 O O   . ARG   B 2 100 ? 143.943 156.612 144.715 1.00 73.86  ? 102 ARG   C O   1 
ATOM   2761 C CB  . ARG   B 2 100 ? 146.806 156.961 145.783 1.00 66.65  ? 102 ARG   C CB  1 
ATOM   2762 C CG  . ARG   B 2 100 ? 147.669 156.008 146.580 1.00 59.74  ? 102 ARG   C CG  1 
ATOM   2763 C CD  . ARG   B 2 100 ? 148.328 156.735 147.736 1.00 55.98  ? 102 ARG   C CD  1 
ATOM   2764 N NE  . ARG   B 2 100 ? 149.487 157.506 147.303 1.00 47.31  ? 102 ARG   C NE  1 
ATOM   2765 C CZ  . ARG   B 2 100 ? 150.691 156.994 147.092 1.00 48.71  ? 102 ARG   C CZ  1 
ATOM   2766 N NH1 . ARG   B 2 100 ? 150.939 155.710 147.282 1.00 47.39  ? 102 ARG   C NH1 1 
ATOM   2767 N NH2 . ARG   B 2 100 ? 151.673 157.793 146.685 1.00 51.13  ? 102 ARG   C NH2 1 
ATOM   2768 N N   . THR   B 2 101 ? 144.784 154.519 144.543 1.00 69.57  ? 103 THR   C N   1 
ATOM   2769 C CA  . THR   B 2 101 ? 143.472 153.897 144.695 1.00 69.07  ? 103 THR   C CA  1 
ATOM   2770 C C   . THR   B 2 101 ? 142.879 154.192 146.067 1.00 69.63  ? 103 THR   C C   1 
ATOM   2771 O O   . THR   B 2 101 ? 141.687 154.498 146.183 1.00 73.81  ? 103 THR   C O   1 
ATOM   2772 C CB  . THR   B 2 101 ? 143.575 152.390 144.471 1.00 65.08  ? 103 THR   C CB  1 
ATOM   2773 O OG1 . THR   B 2 101 ? 144.575 152.119 143.480 1.00 67.15  ? 103 THR   C OG1 1 
ATOM   2774 C CG2 . THR   B 2 101 ? 142.240 151.830 144.004 1.00 65.24  ? 103 THR   C CG2 1 
ATOM   2775 N N   . GLY   B 2 102 ? 143.697 154.109 147.114 1.00 63.70  ? 104 GLY   C N   1 
ATOM   2776 C CA  . GLY   B 2 102 ? 143.263 154.436 148.456 1.00 60.07  ? 104 GLY   C CA  1 
ATOM   2777 C C   . GLY   B 2 102 ? 144.386 155.123 149.199 1.00 60.14  ? 104 GLY   C C   1 
ATOM   2778 O O   . GLY   B 2 102 ? 145.519 155.199 148.720 1.00 60.39  ? 104 GLY   C O   1 
ATOM   2779 N N   . ILE   B 2 103 ? 144.055 155.631 150.388 1.00 55.02  ? 105 ILE   C N   1 
ATOM   2780 C CA  . ILE   B 2 103 ? 145.053 156.323 151.199 1.00 44.65  ? 105 ILE   C CA  1 
ATOM   2781 C C   . ILE   B 2 103 ? 146.190 155.377 151.566 1.00 41.25  ? 105 ILE   C C   1 
ATOM   2782 O O   . ILE   B 2 103 ? 147.362 155.771 151.595 1.00 35.72  ? 105 ILE   C O   1 
ATOM   2783 C CB  . ILE   B 2 103 ? 144.390 156.940 152.445 1.00 49.10  ? 105 ILE   C CB  1 
ATOM   2784 C CG1 . ILE   B 2 103 ? 145.447 157.414 153.446 1.00 42.65  ? 105 ILE   C CG1 1 
ATOM   2785 C CG2 . ILE   B 2 103 ? 143.429 155.951 153.086 1.00 48.62  ? 105 ILE   C CG2 1 
ATOM   2786 C CD1 . ILE   B 2 103 ? 144.865 158.004 154.708 1.00 29.68  ? 105 ILE   C CD1 1 
ATOM   2787 N N   . TRP   B 2 104 ? 145.866 154.112 151.832 1.00 44.79  ? 106 TRP   C N   1 
ATOM   2788 C CA  . TRP   B 2 104 ? 146.861 153.108 152.183 1.00 44.11  ? 106 TRP   C CA  1 
ATOM   2789 C C   . TRP   B 2 104 ? 147.415 152.364 150.974 1.00 44.84  ? 106 TRP   C C   1 
ATOM   2790 O O   . TRP   B 2 104 ? 148.228 151.450 151.150 1.00 43.77  ? 106 TRP   C O   1 
ATOM   2791 C CB  . TRP   B 2 104 ? 146.266 152.094 153.168 1.00 37.85  ? 106 TRP   C CB  1 
ATOM   2792 C CG  . TRP   B 2 104 ? 145.482 152.717 154.283 1.00 31.03  ? 106 TRP   C CG  1 
ATOM   2793 C CD1 . TRP   B 2 104 ? 144.126 152.726 154.426 1.00 28.78  ? 106 TRP   C CD1 1 
ATOM   2794 C CD2 . TRP   B 2 104 ? 146.009 153.419 155.415 1.00 29.10  ? 106 TRP   C CD2 1 
ATOM   2795 N NE1 . TRP   B 2 104 ? 143.775 153.392 155.574 1.00 29.66  ? 106 TRP   C NE1 1 
ATOM   2796 C CE2 . TRP   B 2 104 ? 144.913 153.828 156.199 1.00 29.61  ? 106 TRP   C CE2 1 
ATOM   2797 C CE3 . TRP   B 2 104 ? 147.300 153.743 155.839 1.00 28.68  ? 106 TRP   C CE3 1 
ATOM   2798 C CZ2 . TRP   B 2 104 ? 145.069 154.543 157.383 1.00 27.80  ? 106 TRP   C CZ2 1 
ATOM   2799 C CZ3 . TRP   B 2 104 ? 147.452 154.453 157.014 1.00 28.06  ? 106 TRP   C CZ3 1 
ATOM   2800 C CH2 . TRP   B 2 104 ? 146.344 154.845 157.772 1.00 25.53  ? 106 TRP   C CH2 1 
ATOM   2801 N N   . GLU   B 2 105 ? 147.001 152.725 149.763 1.00 45.83  ? 107 GLU   C N   1 
ATOM   2802 C CA  . GLU   B 2 105 ? 147.438 152.014 148.572 1.00 47.40  ? 107 GLU   C CA  1 
ATOM   2803 C C   . GLU   B 2 105 ? 148.717 152.629 148.008 1.00 54.37  ? 107 GLU   C C   1 
ATOM   2804 O O   . GLU   B 2 105 ? 149.212 153.653 148.485 1.00 53.31  ? 107 GLU   C O   1 
ATOM   2805 C CB  . GLU   B 2 105 ? 146.339 152.022 147.509 1.00 52.82  ? 107 GLU   C CB  1 
ATOM   2806 N N   . GLU   B 2 106 ? 149.247 151.984 146.973 1.00 61.28  ? 108 GLU   C N   1 
ATOM   2807 C CA  . GLU   B 2 106 ? 150.485 152.420 146.348 1.00 59.15  ? 108 GLU   C CA  1 
ATOM   2808 C C   . GLU   B 2 106 ? 150.206 153.389 145.203 1.00 57.52  ? 108 GLU   C C   1 
ATOM   2809 O O   . GLU   B 2 106 ? 149.071 153.549 144.747 1.00 57.26  ? 108 GLU   C O   1 
ATOM   2810 C CB  . GLU   B 2 106 ? 151.277 151.220 145.825 1.00 58.08  ? 108 GLU   C CB  1 
ATOM   2811 N N   . LEU   B 2 107 ? 151.270 154.039 144.739 1.00 58.03  ? 109 LEU   C N   1 
ATOM   2812 C CA  . LEU   B 2 107 ? 151.152 154.947 143.607 1.00 58.86  ? 109 LEU   C CA  1 
ATOM   2813 C C   . LEU   B 2 107 ? 151.002 154.155 142.316 1.00 62.00  ? 109 LEU   C C   1 
ATOM   2814 O O   . LEU   B 2 107 ? 151.784 153.243 142.032 1.00 61.73  ? 109 LEU   C O   1 
ATOM   2815 C CB  . LEU   B 2 107 ? 152.372 155.864 143.527 1.00 60.65  ? 109 LEU   C CB  1 
ATOM   2816 C CG  . LEU   B 2 107 ? 152.243 157.054 142.575 1.00 62.97  ? 109 LEU   C CG  1 
ATOM   2817 C CD1 . LEU   B 2 107 ? 151.196 158.035 143.082 1.00 61.08  ? 109 LEU   C CD1 1 
ATOM   2818 C CD2 . LEU   B 2 107 ? 153.583 157.744 142.384 1.00 62.74  ? 109 LEU   C CD2 1 
ATOM   2819 N N   . LEU   B 2 108 ? 149.991 154.510 141.529 1.00 63.98  ? 110 LEU   C N   1 
ATOM   2820 C CA  . LEU   B 2 108 ? 149.642 153.768 140.330 1.00 65.56  ? 110 LEU   C CA  1 
ATOM   2821 C C   . LEU   B 2 108 ? 149.403 154.737 139.181 1.00 68.65  ? 110 LEU   C C   1 
ATOM   2822 O O   . LEU   B 2 108 ? 148.844 155.822 139.359 1.00 68.56  ? 110 LEU   C O   1 
ATOM   2823 C CB  . LEU   B 2 108 ? 148.408 152.879 140.579 1.00 63.69  ? 110 LEU   C CB  1 
ATOM   2824 C CG  . LEU   B 2 108 ? 147.586 152.289 139.431 1.00 68.53  ? 110 LEU   C CG  1 
ATOM   2825 C CD1 . LEU   B 2 108 ? 146.979 150.971 139.872 1.00 71.60  ? 110 LEU   C CD1 1 
ATOM   2826 C CD2 . LEU   B 2 108 ? 146.482 153.238 139.000 1.00 74.52  ? 110 LEU   C CD2 1 
ATOM   2827 N N   . ASP   B 2 109 ? 149.836 154.326 137.992 1.00 71.55  ? 111 ASP   C N   1 
ATOM   2828 C CA  . ASP   B 2 109 ? 149.697 155.118 136.780 1.00 75.57  ? 111 ASP   C CA  1 
ATOM   2829 C C   . ASP   B 2 109 ? 148.490 154.642 135.984 1.00 77.01  ? 111 ASP   C C   1 
ATOM   2830 O O   . ASP   B 2 109 ? 148.104 153.471 136.049 1.00 78.20  ? 111 ASP   C O   1 
ATOM   2831 C CB  . ASP   B 2 109 ? 150.955 155.032 135.905 1.00 77.77  ? 111 ASP   C CB  1 
ATOM   2832 C CG  . ASP   B 2 109 ? 152.150 155.720 136.532 1.00 81.61  ? 111 ASP   C CG  1 
ATOM   2833 O OD1 . ASP   B 2 109 ? 151.949 156.707 137.270 1.00 86.42  ? 111 ASP   C OD1 1 
ATOM   2834 O OD2 . ASP   B 2 109 ? 153.291 155.277 136.283 1.00 78.90  ? 111 ASP   C OD2 1 
ATOM   2835 N N   . GLY   B 2 110 ? 147.897 155.565 135.233 1.00 78.50  ? 112 GLY   C N   1 
ATOM   2836 C CA  . GLY   B 2 110 ? 146.765 155.242 134.388 1.00 75.10  ? 112 GLY   C CA  1 
ATOM   2837 C C   . GLY   B 2 110 ? 146.873 155.865 133.012 1.00 64.53  ? 112 GLY   C C   1 
ATOM   2838 O O   . GLY   B 2 110 ? 147.217 157.044 132.884 1.00 58.77  ? 112 GLY   C O   1 
ATOM   2839 N N   . TRP   B 2 111 ? 146.577 155.086 131.975 1.00 63.99  ? 113 TRP   C N   1 
ATOM   2840 C CA  . TRP   B 2 111 ? 146.682 155.534 130.594 1.00 59.57  ? 113 TRP   C CA  1 
ATOM   2841 C C   . TRP   B 2 111 ? 145.291 155.795 130.039 1.00 58.63  ? 113 TRP   C C   1 
ATOM   2842 O O   . TRP   B 2 111 ? 144.395 154.955 130.177 1.00 58.02  ? 113 TRP   C O   1 
ATOM   2843 C CB  . TRP   B 2 111 ? 147.400 154.498 129.726 1.00 58.43  ? 113 TRP   C CB  1 
ATOM   2844 C CG  . TRP   B 2 111 ? 148.890 154.567 129.794 1.00 60.30  ? 113 TRP   C CG  1 
ATOM   2845 C CD1 . TRP   B 2 111 ? 149.715 153.759 130.517 1.00 62.03  ? 113 TRP   C CD1 1 
ATOM   2846 C CD2 . TRP   B 2 111 ? 149.739 155.493 129.105 1.00 56.39  ? 113 TRP   C CD2 1 
ATOM   2847 N NE1 . TRP   B 2 111 ? 151.025 154.123 130.324 1.00 60.98  ? 113 TRP   C NE1 1 
ATOM   2848 C CE2 . TRP   B 2 111 ? 151.067 155.186 129.461 1.00 55.54  ? 113 TRP   C CE2 1 
ATOM   2849 C CE3 . TRP   B 2 111 ? 149.506 156.553 128.223 1.00 52.03  ? 113 TRP   C CE3 1 
ATOM   2850 C CZ2 . TRP   B 2 111 ? 152.156 155.900 128.966 1.00 51.55  ? 113 TRP   C CZ2 1 
ATOM   2851 C CZ3 . TRP   B 2 111 ? 150.589 157.259 127.733 1.00 49.69  ? 113 TRP   C CZ3 1 
ATOM   2852 C CH2 . TRP   B 2 111 ? 151.897 156.930 128.106 1.00 50.10  ? 113 TRP   C CH2 1 
ATOM   2853 N N   . GLY   B 2 112 ? 145.115 156.955 129.416 1.00 60.19  ? 114 GLY   C N   1 
ATOM   2854 C CA  . GLY   B 2 112 ? 143.862 157.264 128.768 1.00 61.87  ? 114 GLY   C CA  1 
ATOM   2855 C C   . GLY   B 2 112 ? 143.720 156.553 127.439 1.00 64.66  ? 114 GLY   C C   1 
ATOM   2856 O O   . GLY   B 2 112 ? 144.667 155.987 126.894 1.00 62.60  ? 114 GLY   C O   1 
ATOM   2857 N N   . LYS   B 2 113 ? 142.499 156.591 126.909 1.00 68.99  ? 115 LYS   C N   1 
ATOM   2858 C CA  . LYS   B 2 113 ? 142.202 155.929 125.647 1.00 55.69  ? 115 LYS   C CA  1 
ATOM   2859 C C   . LYS   B 2 113 ? 142.766 156.663 124.438 1.00 46.38  ? 115 LYS   C C   1 
ATOM   2860 O O   . LYS   B 2 113 ? 142.931 156.043 123.383 1.00 45.80  ? 115 LYS   C O   1 
ATOM   2861 C CB  . LYS   B 2 113 ? 140.689 155.764 125.490 1.00 55.60  ? 115 LYS   C CB  1 
ATOM   2862 C CG  . LYS   B 2 113 ? 140.108 154.560 126.208 1.00 58.60  ? 115 LYS   C CG  1 
ATOM   2863 C CD  . LYS   B 2 113 ? 139.248 153.731 125.266 1.00 58.36  ? 115 LYS   C CD  1 
ATOM   2864 C CE  . LYS   B 2 113 ? 138.840 152.411 125.900 1.00 55.82  ? 115 LYS   C CE  1 
ATOM   2865 N NZ  . LYS   B 2 113 ? 138.112 151.539 124.939 1.00 58.89  ? 115 LYS   C NZ  1 
ATOM   2866 N N   . GLY   B 2 114 ? 143.069 157.952 124.560 1.00 43.58  ? 116 GLY   C N   1 
ATOM   2867 C CA  . GLY   B 2 114 ? 143.634 158.698 123.453 1.00 39.01  ? 116 GLY   C CA  1 
ATOM   2868 C C   . GLY   B 2 114 ? 142.598 159.416 122.616 1.00 36.12  ? 116 GLY   C C   1 
ATOM   2869 O O   . GLY   B 2 114 ? 141.519 158.877 122.358 1.00 39.86  ? 116 GLY   C O   1 
ATOM   2870 N N   . THR   B 2 115 ? 142.912 160.638 122.190 1.00 28.96  ? 117 THR   C N   1 
ATOM   2871 C CA  . THR   B 2 115 ? 142.021 161.402 121.325 1.00 27.22  ? 117 THR   C CA  1 
ATOM   2872 C C   . THR   B 2 115 ? 142.730 161.718 120.016 1.00 30.79  ? 117 THR   C C   1 
ATOM   2873 O O   . THR   B 2 115 ? 143.911 162.099 120.034 1.00 31.27  ? 117 THR   C O   1 
ATOM   2874 C CB  . THR   B 2 115 ? 141.558 162.689 122.014 1.00 32.82  ? 117 THR   C CB  1 
ATOM   2875 O OG1 . THR   B 2 115 ? 140.754 163.459 121.111 1.00 33.95  ? 117 THR   C OG1 1 
ATOM   2876 C CG2 . THR   B 2 115 ? 142.741 163.520 122.477 1.00 36.88  ? 117 THR   C CG2 1 
ATOM   2877 N N   . PRO   B 2 116 ? 142.078 161.548 118.867 1.00 30.57  ? 118 PRO   C N   1 
ATOM   2878 C CA  . PRO   B 2 116 ? 142.738 161.842 117.591 1.00 22.64  ? 118 PRO   C CA  1 
ATOM   2879 C C   . PRO   B 2 116 ? 142.545 163.290 117.167 1.00 22.57  ? 118 PRO   C C   1 
ATOM   2880 O O   . PRO   B 2 116 ? 141.431 163.820 117.171 1.00 26.44  ? 118 PRO   C O   1 
ATOM   2881 C CB  . PRO   B 2 116 ? 142.045 160.885 116.616 1.00 22.59  ? 118 PRO   C CB  1 
ATOM   2882 C CG  . PRO   B 2 116 ? 140.673 160.724 117.182 1.00 23.31  ? 118 PRO   C CG  1 
ATOM   2883 C CD  . PRO   B 2 116 ? 140.772 160.893 118.678 1.00 30.47  ? 118 PRO   C CD  1 
ATOM   2884 N N   . VAL   B 2 117 ? 143.653 163.927 116.793 1.00 18.02  ? 119 VAL   C N   1 
ATOM   2885 C CA  . VAL   B 2 117 ? 143.663 165.303 116.311 1.00 18.71  ? 119 VAL   C CA  1 
ATOM   2886 C C   . VAL   B 2 117 ? 144.292 165.334 114.926 1.00 16.95  ? 119 VAL   C C   1 
ATOM   2887 O O   . VAL   B 2 117 ? 145.407 164.835 114.734 1.00 15.45  ? 119 VAL   C O   1 
ATOM   2888 C CB  . VAL   B 2 117 ? 144.425 166.242 117.265 1.00 20.63  ? 119 VAL   C CB  1 
ATOM   2889 C CG1 . VAL   B 2 117 ? 144.250 167.685 116.835 1.00 23.88  ? 119 VAL   C CG1 1 
ATOM   2890 C CG2 . VAL   B 2 117 ? 143.935 166.055 118.689 1.00 22.74  ? 119 VAL   C CG2 1 
ATOM   2891 N N   . THR   B 2 118 ? 143.579 165.920 113.965 1.00 17.24  ? 120 THR   C N   1 
ATOM   2892 C CA  . THR   B 2 118 ? 144.082 166.119 112.611 1.00 16.46  ? 120 THR   C CA  1 
ATOM   2893 C C   . THR   B 2 118 ? 143.886 167.580 112.220 1.00 20.90  ? 120 THR   C C   1 
ATOM   2894 O O   . THR   B 2 118 ? 142.786 168.128 112.358 1.00 23.11  ? 120 THR   C O   1 
ATOM   2895 C CB  . THR   B 2 118 ? 143.410 165.155 111.619 1.00 16.32  ? 120 THR   C CB  1 
ATOM   2896 O OG1 . THR   B 2 118 ? 144.241 164.997 110.461 1.00 18.74  ? 120 THR   C OG1 1 
ATOM   2897 C CG2 . THR   B 2 118 ? 142.014 165.609 111.192 1.00 22.14  ? 120 THR   C CG2 1 
ATOM   2898 N N   . VAL   B 2 119 ? 144.975 168.232 111.813 1.00 20.13  ? 121 VAL   C N   1 
ATOM   2899 C CA  . VAL   B 2 119 ? 144.923 169.628 111.398 1.00 21.38  ? 121 VAL   C CA  1 
ATOM   2900 C C   . VAL   B 2 119 ? 144.958 169.714 109.878 1.00 22.45  ? 121 VAL   C C   1 
ATOM   2901 O O   . VAL   B 2 119 ? 146.034 169.824 109.279 1.00 23.51  ? 121 VAL   C O   1 
ATOM   2902 C CB  . VAL   B 2 119 ? 146.076 170.434 112.022 1.00 20.60  ? 121 VAL   C CB  1 
ATOM   2903 N N   . SER   B 2 120 ? 143.783 169.685 109.252 1.00 21.56  ? 122 SER   C N   1 
ATOM   2904 C CA  . SER   B 2 120 ? 143.654 169.826 107.809 1.00 19.82  ? 122 SER   C CA  1 
ATOM   2905 C C   . SER   B 2 120 ? 142.176 169.876 107.451 1.00 24.36  ? 122 SER   C C   1 
ATOM   2906 O O   . SER   B 2 120 ? 141.344 169.243 108.107 1.00 24.34  ? 122 SER   C O   1 
ATOM   2907 C CB  . SER   B 2 120 ? 144.338 168.680 107.053 1.00 16.91  ? 122 SER   C CB  1 
ATOM   2908 N N   . SER   B 2 121 ? 141.861 170.627 106.399 1.00 21.88  ? 123 SER   C N   1 
ATOM   2909 C CA  . SER   B 2 121 ? 140.490 170.730 105.907 1.00 19.80  ? 123 SER   C CA  1 
ATOM   2910 C C   . SER   B 2 121 ? 140.465 171.318 104.502 1.00 17.03  ? 123 SER   C C   1 
ATOM   2911 O O   . SER   B 2 121 ? 141.200 172.258 104.203 1.00 16.18  ? 123 SER   C O   1 
ATOM   2912 C CB  . SER   B 2 121 ? 139.635 171.584 106.845 1.00 23.25  ? 123 SER   C CB  1 
ATOM   2913 N N   . VAL   C 3 5   ? 161.861 150.271 113.501 1.00 60.61  ? 2   VAL   H N   1 
ATOM   2914 C CA  . VAL   C 3 5   ? 160.798 149.313 113.773 1.00 67.34  ? 2   VAL   H CA  1 
ATOM   2915 C C   . VAL   C 3 5   ? 160.831 148.213 112.718 1.00 67.07  ? 2   VAL   H C   1 
ATOM   2916 O O   . VAL   C 3 5   ? 160.785 148.489 111.519 1.00 62.83  ? 2   VAL   H O   1 
ATOM   2917 C CB  . VAL   C 3 5   ? 159.421 150.005 113.820 1.00 61.02  ? 2   VAL   H CB  1 
ATOM   2918 C CG1 . VAL   C 3 5   ? 158.311 149.037 113.427 1.00 52.56  ? 2   VAL   H CG1 1 
ATOM   2919 C CG2 . VAL   C 3 5   ? 159.168 150.592 115.199 1.00 66.71  ? 2   VAL   H CG2 1 
ATOM   2920 N N   . GLN   C 3 6   ? 160.920 146.964 113.170 1.00 67.72  ? 3   GLN   H N   1 
ATOM   2921 C CA  . GLN   C 3 6   ? 161.026 145.812 112.285 1.00 63.60  ? 3   GLN   H CA  1 
ATOM   2922 C C   . GLN   C 3 6   ? 159.877 144.852 112.546 1.00 63.64  ? 3   GLN   H C   1 
ATOM   2923 O O   . GLN   C 3 6   ? 159.567 144.549 113.703 1.00 70.19  ? 3   GLN   H O   1 
ATOM   2924 C CB  . GLN   C 3 6   ? 162.364 145.088 112.476 1.00 68.87  ? 3   GLN   H CB  1 
ATOM   2925 C CG  . GLN   C 3 6   ? 163.587 145.960 112.250 1.00 70.38  ? 3   GLN   H CG  1 
ATOM   2926 C CD  . GLN   C 3 6   ? 163.716 146.417 110.810 1.00 75.34  ? 3   GLN   H CD  1 
ATOM   2927 O OE1 . GLN   C 3 6   ? 163.224 147.482 110.438 1.00 76.12  ? 3   GLN   H OE1 1 
ATOM   2928 N NE2 . GLN   C 3 6   ? 164.381 145.611 109.991 1.00 79.96  ? 3   GLN   H NE2 1 
ATOM   2929 N N   . LEU   C 3 7   ? 159.246 144.384 111.473 1.00 56.27  ? 4   LEU   H N   1 
ATOM   2930 C CA  . LEU   C 3 7   ? 158.266 143.309 111.530 1.00 60.54  ? 4   LEU   H CA  1 
ATOM   2931 C C   . LEU   C 3 7   ? 158.670 142.229 110.538 1.00 65.76  ? 4   LEU   H C   1 
ATOM   2932 O O   . LEU   C 3 7   ? 158.753 142.488 109.333 1.00 63.33  ? 4   LEU   H O   1 
ATOM   2933 C CB  . LEU   C 3 7   ? 156.855 143.820 111.224 1.00 56.15  ? 4   LEU   H CB  1 
ATOM   2934 C CG  . LEU   C 3 7   ? 155.992 144.225 112.422 1.00 47.92  ? 4   LEU   H CG  1 
ATOM   2935 C CD1 . LEU   C 3 7   ? 156.459 145.545 113.008 1.00 55.52  ? 4   LEU   H CD1 1 
ATOM   2936 C CD2 . LEU   C 3 7   ? 154.526 144.303 112.025 1.00 33.71  ? 4   LEU   H CD2 1 
ATOM   2937 N N   . VAL   C 3 8   ? 158.928 141.025 111.046 1.00 63.44  ? 5   VAL   H N   1 
ATOM   2938 C CA  . VAL   C 3 8   ? 159.342 139.896 110.224 1.00 66.64  ? 5   VAL   H CA  1 
ATOM   2939 C C   . VAL   C 3 8   ? 158.335 138.771 110.404 1.00 66.58  ? 5   VAL   H C   1 
ATOM   2940 O O   . VAL   C 3 8   ? 157.967 138.419 111.529 1.00 66.57  ? 5   VAL   H O   1 
ATOM   2941 C CB  . VAL   C 3 8   ? 160.765 139.411 110.577 1.00 70.77  ? 5   VAL   H CB  1 
ATOM   2942 C CG1 . VAL   C 3 8   ? 161.297 138.493 109.491 1.00 72.11  ? 5   VAL   H CG1 1 
ATOM   2943 C CG2 . VAL   C 3 8   ? 161.694 140.596 110.781 1.00 72.92  ? 5   VAL   H CG2 1 
ATOM   2944 N N   . GLU   C 3 9   ? 157.908 138.187 109.285 1.00 67.72  ? 6   GLU   H N   1 
ATOM   2945 C CA  . GLU   C 3 9   ? 156.838 137.202 109.278 1.00 66.12  ? 6   GLU   H CA  1 
ATOM   2946 C C   . GLU   C 3 9   ? 157.395 135.820 108.970 1.00 73.38  ? 6   GLU   H C   1 
ATOM   2947 O O   . GLU   C 3 9   ? 158.290 135.663 108.135 1.00 70.50  ? 6   GLU   H O   1 
ATOM   2948 C CB  . GLU   C 3 9   ? 155.753 137.565 108.254 1.00 56.50  ? 6   GLU   H CB  1 
ATOM   2949 N N   . SER   C 3 10  ? 156.851 134.818 109.658 1.00 79.08  ? 7   SER   H N   1 
ATOM   2950 C CA  . SER   C 3 10  ? 157.279 133.438 109.483 1.00 77.91  ? 7   SER   H CA  1 
ATOM   2951 C C   . SER   C 3 10  ? 156.161 132.505 109.925 1.00 74.20  ? 7   SER   H C   1 
ATOM   2952 O O   . SER   C 3 10  ? 155.221 132.909 110.615 1.00 67.24  ? 7   SER   H O   1 
ATOM   2953 C CB  . SER   C 3 10  ? 158.564 133.143 110.267 1.00 78.10  ? 7   SER   H CB  1 
ATOM   2954 O OG  . SER   C 3 10  ? 159.708 133.305 109.448 1.00 81.16  ? 7   SER   H OG  1 
ATOM   2955 N N   . GLY   C 3 11  ? 156.280 131.244 109.519 1.00 78.49  ? 8   GLY   H N   1 
ATOM   2956 C CA  . GLY   C 3 11  ? 155.315 130.225 109.869 1.00 74.25  ? 8   GLY   H CA  1 
ATOM   2957 C C   . GLY   C 3 11  ? 154.509 129.659 108.722 1.00 76.36  ? 8   GLY   H C   1 
ATOM   2958 O O   . GLY   C 3 11  ? 153.675 128.776 108.954 1.00 78.96  ? 8   GLY   H O   1 
ATOM   2959 N N   . GLY   C 3 12  ? 154.726 130.133 107.497 1.00 69.54  ? 9   GLY   H N   1 
ATOM   2960 C CA  . GLY   C 3 12  ? 153.967 129.661 106.355 1.00 62.24  ? 9   GLY   H CA  1 
ATOM   2961 C C   . GLY   C 3 12  ? 154.673 128.576 105.568 1.00 65.02  ? 9   GLY   H C   1 
ATOM   2962 O O   . GLY   C 3 12  ? 155.894 128.621 105.394 1.00 74.61  ? 9   GLY   H O   1 
ATOM   2963 N N   . GLY   C 3 13  ? 153.914 127.595 105.088 1.00 56.14  ? 10  GLY   H N   1 
ATOM   2964 C CA  . GLY   C 3 13  ? 154.491 126.500 104.334 1.00 48.87  ? 10  GLY   H CA  1 
ATOM   2965 C C   . GLY   C 3 13  ? 153.426 125.774 103.544 1.00 42.87  ? 10  GLY   H C   1 
ATOM   2966 O O   . GLY   C 3 13  ? 152.264 126.184 103.499 1.00 42.68  ? 10  GLY   H O   1 
ATOM   2967 N N   . LEU   C 3 14  ? 153.843 124.680 102.910 1.00 39.75  ? 11  LEU   H N   1 
ATOM   2968 C CA  . LEU   C 3 14  ? 152.922 123.886 102.108 1.00 40.16  ? 11  LEU   H CA  1 
ATOM   2969 C C   . LEU   C 3 14  ? 151.916 123.173 103.004 1.00 37.95  ? 11  LEU   H C   1 
ATOM   2970 O O   . LEU   C 3 14  ? 152.288 122.525 103.986 1.00 40.96  ? 11  LEU   H O   1 
ATOM   2971 C CB  . LEU   C 3 14  ? 153.695 122.873 101.261 1.00 38.62  ? 11  LEU   H CB  1 
ATOM   2972 C CG  . LEU   C 3 14  ? 154.529 123.436 100.106 1.00 39.37  ? 11  LEU   H CG  1 
ATOM   2973 C CD1 . LEU   C 3 14  ? 155.930 123.808 100.568 1.00 37.63  ? 11  LEU   H CD1 1 
ATOM   2974 C CD2 . LEU   C 3 14  ? 154.588 122.451 98.950  1.00 39.85  ? 11  LEU   H CD2 1 
ATOM   2975 N N   . VAL   C 3 15  ? 150.634 123.298 102.657 1.00 38.38  ? 12  VAL   H N   1 
ATOM   2976 C CA  . VAL   C 3 15  ? 149.534 122.743 103.436 1.00 37.77  ? 12  VAL   H CA  1 
ATOM   2977 C C   . VAL   C 3 15  ? 148.623 121.975 102.484 1.00 38.51  ? 12  VAL   H C   1 
ATOM   2978 O O   . VAL   C 3 15  ? 148.626 122.196 101.272 1.00 37.97  ? 12  VAL   H O   1 
ATOM   2979 C CB  . VAL   C 3 15  ? 148.742 123.844 104.185 1.00 37.71  ? 12  VAL   H CB  1 
ATOM   2980 C CG1 . VAL   C 3 15  ? 147.757 123.246 105.182 1.00 41.43  ? 12  VAL   H CG1 1 
ATOM   2981 C CG2 . VAL   C 3 15  ? 149.686 124.807 104.887 1.00 36.04  ? 12  VAL   H CG2 1 
ATOM   2982 N N   . GLN   C 3 16  ? 147.853 121.050 103.043 1.00 40.64  ? 13  GLN   H N   1 
ATOM   2983 C CA  . GLN   C 3 16  ? 146.803 120.338 102.336 1.00 44.42  ? 13  GLN   H CA  1 
ATOM   2984 C C   . GLN   C 3 16  ? 145.453 120.958 102.668 1.00 41.88  ? 13  GLN   H C   1 
ATOM   2985 O O   . GLN   C 3 16  ? 145.277 121.539 103.745 1.00 41.72  ? 13  GLN   H O   1 
ATOM   2986 C CB  . GLN   C 3 16  ? 146.800 118.847 102.705 1.00 49.27  ? 13  GLN   H CB  1 
ATOM   2987 C CG  . GLN   C 3 16  ? 147.884 118.030 102.013 1.00 49.75  ? 13  GLN   H CG  1 
ATOM   2988 C CD  . GLN   C 3 16  ? 149.252 118.217 102.638 1.00 51.32  ? 13  GLN   H CD  1 
ATOM   2989 O OE1 . GLN   C 3 16  ? 150.198 118.639 101.974 1.00 51.18  ? 13  GLN   H OE1 1 
ATOM   2990 N NE2 . GLN   C 3 16  ? 149.363 117.901 103.923 1.00 50.52  ? 13  GLN   H NE2 1 
ATOM   2991 N N   . PRO   C 3 17  ? 144.481 120.872 101.759 1.00 41.30  ? 14  PRO   H N   1 
ATOM   2992 C CA  . PRO   C 3 17  ? 143.171 121.479 102.026 1.00 42.73  ? 14  PRO   H CA  1 
ATOM   2993 C C   . PRO   C 3 17  ? 142.506 120.864 103.248 1.00 50.25  ? 14  PRO   H C   1 
ATOM   2994 O O   . PRO   C 3 17  ? 142.628 119.667 103.511 1.00 56.53  ? 14  PRO   H O   1 
ATOM   2995 C CB  . PRO   C 3 17  ? 142.375 121.190 100.747 1.00 46.52  ? 14  PRO   H CB  1 
ATOM   2996 C CG  . PRO   C 3 17  ? 143.121 120.096 100.054 1.00 44.41  ? 14  PRO   H CG  1 
ATOM   2997 C CD  . PRO   C 3 17  ? 144.556 120.290 100.410 1.00 44.43  ? 14  PRO   H CD  1 
ATOM   2998 N N   . GLY   C 3 18  ? 141.797 121.704 104.000 1.00 53.73  ? 15  GLY   H N   1 
ATOM   2999 C CA  . GLY   C 3 18  ? 141.122 121.274 105.205 1.00 53.32  ? 15  GLY   H CA  1 
ATOM   3000 C C   . GLY   C 3 18  ? 141.998 121.178 106.433 1.00 53.39  ? 15  GLY   H C   1 
ATOM   3001 O O   . GLY   C 3 18  ? 141.489 120.833 107.508 1.00 62.93  ? 15  GLY   H O   1 
ATOM   3002 N N   . GLY   C 3 19  ? 143.291 121.475 106.318 1.00 51.70  ? 16  GLY   H N   1 
ATOM   3003 C CA  . GLY   C 3 19  ? 144.188 121.366 107.447 1.00 57.02  ? 16  GLY   H CA  1 
ATOM   3004 C C   . GLY   C 3 19  ? 144.172 122.595 108.335 1.00 59.68  ? 16  GLY   H C   1 
ATOM   3005 O O   . GLY   C 3 19  ? 143.273 123.433 108.282 1.00 60.27  ? 16  GLY   H O   1 
ATOM   3006 N N   . SER   C 3 20  ? 145.199 122.689 109.177 1.00 59.89  ? 17  SER   H N   1 
ATOM   3007 C CA  . SER   C 3 20  ? 145.356 123.800 110.102 1.00 61.93  ? 17  SER   H CA  1 
ATOM   3008 C C   . SER   C 3 20  ? 146.785 124.317 110.046 1.00 62.90  ? 17  SER   H C   1 
ATOM   3009 O O   . SER   C 3 20  ? 147.732 123.538 109.899 1.00 61.48  ? 17  SER   H O   1 
ATOM   3010 C CB  . SER   C 3 20  ? 145.005 123.388 111.537 1.00 57.32  ? 17  SER   H CB  1 
ATOM   3011 N N   . LEU   C 3 21  ? 146.934 125.635 110.161 1.00 59.24  ? 18  LEU   H N   1 
ATOM   3012 C CA  . LEU   C 3 21  ? 148.241 126.275 110.172 1.00 52.61  ? 18  LEU   H CA  1 
ATOM   3013 C C   . LEU   C 3 21  ? 148.230 127.422 111.170 1.00 52.54  ? 18  LEU   H C   1 
ATOM   3014 O O   . LEU   C 3 21  ? 147.215 128.100 111.350 1.00 55.35  ? 18  LEU   H O   1 
ATOM   3015 C CB  . LEU   C 3 21  ? 148.632 126.789 108.780 1.00 53.67  ? 18  LEU   H CB  1 
ATOM   3016 N N   . ARG   C 3 22  ? 149.373 127.633 111.818 1.00 53.96  ? 19  ARG   H N   1 
ATOM   3017 C CA  . ARG   C 3 22  ? 149.538 128.687 112.810 1.00 55.30  ? 19  ARG   H CA  1 
ATOM   3018 C C   . ARG   C 3 22  ? 150.655 129.622 112.372 1.00 49.71  ? 19  ARG   H C   1 
ATOM   3019 O O   . ARG   C 3 22  ? 151.793 129.186 112.172 1.00 47.51  ? 19  ARG   H O   1 
ATOM   3020 C CB  . ARG   C 3 22  ? 149.845 128.102 114.192 1.00 55.04  ? 19  ARG   H CB  1 
ATOM   3021 N N   . LEU   C 3 23  ? 150.327 130.903 112.227 1.00 49.06  ? 20  LEU   H N   1 
ATOM   3022 C CA  . LEU   C 3 23  ? 151.280 131.923 111.816 1.00 54.15  ? 20  LEU   H CA  1 
ATOM   3023 C C   . LEU   C 3 23  ? 151.446 132.961 112.916 1.00 51.13  ? 20  LEU   H C   1 
ATOM   3024 O O   . LEU   C 3 23  ? 150.464 133.412 113.514 1.00 48.41  ? 20  LEU   H O   1 
ATOM   3025 C CB  . LEU   C 3 23  ? 150.837 132.612 110.523 1.00 56.97  ? 20  LEU   H CB  1 
ATOM   3026 C CG  . LEU   C 3 23  ? 151.100 131.889 109.202 1.00 49.05  ? 20  LEU   H CG  1 
ATOM   3027 C CD1 . LEU   C 3 23  ? 149.965 132.127 108.230 1.00 35.44  ? 20  LEU   H CD1 1 
ATOM   3028 C CD2 . LEU   C 3 23  ? 152.413 132.359 108.606 1.00 47.66  ? 20  LEU   H CD2 1 
ATOM   3029 N N   . SER   C 3 24  ? 152.695 133.323 113.186 1.00 51.23  ? 21  SER   H N   1 
ATOM   3030 C CA  . SER   C 3 24  ? 153.025 134.370 114.137 1.00 58.45  ? 21  SER   H CA  1 
ATOM   3031 C C   . SER   C 3 24  ? 154.255 135.127 113.655 1.00 64.45  ? 21  SER   H C   1 
ATOM   3032 O O   . SER   C 3 24  ? 155.244 134.525 113.224 1.00 64.23  ? 21  SER   H O   1 
ATOM   3033 C CB  . SER   C 3 24  ? 153.279 133.797 115.536 1.00 63.19  ? 21  SER   H CB  1 
ATOM   3034 N N   . CYS   C 3 25  ? 154.186 136.453 113.727 1.00 66.77  ? 22  CYS   H N   1 
ATOM   3035 C CA  . CYS   C 3 25  ? 155.310 137.306 113.377 1.00 64.55  ? 22  CYS   H CA  1 
ATOM   3036 C C   . CYS   C 3 25  ? 155.666 138.175 114.573 1.00 60.16  ? 22  CYS   H C   1 
ATOM   3037 O O   . CYS   C 3 25  ? 154.785 138.621 115.315 1.00 53.85  ? 22  CYS   H O   1 
ATOM   3038 C CB  . CYS   C 3 25  ? 155.004 138.176 112.148 1.00 63.13  ? 22  CYS   H CB  1 
ATOM   3039 S SG  . CYS   C 3 25  ? 153.893 139.568 112.386 1.00 71.05  ? 22  CYS   H SG  1 
ATOM   3040 N N   . ALA   C 3 26  ? 156.962 138.401 114.758 1.00 66.08  ? 23  ALA   H N   1 
ATOM   3041 C CA  . ALA   C 3 26  ? 157.484 139.080 115.934 1.00 70.84  ? 23  ALA   H CA  1 
ATOM   3042 C C   . ALA   C 3 26  ? 157.484 140.586 115.715 1.00 71.11  ? 23  ALA   H C   1 
ATOM   3043 O O   . ALA   C 3 26  ? 157.792 141.060 114.617 1.00 65.19  ? 23  ALA   H O   1 
ATOM   3044 C CB  . ALA   C 3 26  ? 158.897 138.593 116.257 1.00 68.42  ? 23  ALA   H CB  1 
ATOM   3045 N N   . ALA   C 3 27  ? 157.138 141.330 116.762 1.00 72.13  ? 24  ALA   H N   1 
ATOM   3046 C CA  . ALA   C 3 27  ? 157.186 142.784 116.759 1.00 59.92  ? 24  ALA   H CA  1 
ATOM   3047 C C   . ALA   C 3 27  ? 158.352 143.232 117.627 1.00 65.51  ? 24  ALA   H C   1 
ATOM   3048 O O   . ALA   C 3 27  ? 158.395 142.918 118.822 1.00 76.52  ? 24  ALA   H O   1 
ATOM   3049 C CB  . ALA   C 3 27  ? 155.874 143.380 117.275 1.00 49.25  ? 24  ALA   H CB  1 
ATOM   3050 N N   . SER   C 3 28  ? 159.291 143.963 117.032 1.00 59.80  ? 25  SER   H N   1 
ATOM   3051 C CA  . SER   C 3 28  ? 160.513 144.334 117.728 1.00 65.26  ? 25  SER   H CA  1 
ATOM   3052 C C   . SER   C 3 28  ? 160.792 145.815 117.522 1.00 73.54  ? 25  SER   H C   1 
ATOM   3053 O O   . SER   C 3 28  ? 160.432 146.384 116.488 1.00 70.25  ? 25  SER   H O   1 
ATOM   3054 C CB  . SER   C 3 28  ? 161.704 143.500 117.243 1.00 63.91  ? 25  SER   H CB  1 
ATOM   3055 N N   . GLY   C 3 29  ? 161.440 146.427 118.512 1.00 76.73  ? 26  GLY   H N   1 
ATOM   3056 C CA  . GLY   C 3 29  ? 161.806 147.825 118.453 1.00 74.22  ? 26  GLY   H CA  1 
ATOM   3057 C C   . GLY   C 3 29  ? 160.788 148.790 119.020 1.00 72.73  ? 26  GLY   H C   1 
ATOM   3058 O O   . GLY   C 3 29  ? 161.011 150.005 118.949 1.00 75.19  ? 26  GLY   H O   1 
ATOM   3059 N N   . PHE   C 3 30  ? 159.684 148.298 119.578 1.00 70.53  ? 27  PHE   H N   1 
ATOM   3060 C CA  . PHE   C 3 30  ? 158.657 149.170 120.127 1.00 65.96  ? 27  PHE   H CA  1 
ATOM   3061 C C   . PHE   C 3 30  ? 157.839 148.406 121.157 1.00 66.50  ? 27  PHE   H C   1 
ATOM   3062 O O   . PHE   C 3 30  ? 157.938 147.182 121.278 1.00 66.66  ? 27  PHE   H O   1 
ATOM   3063 C CB  . PHE   C 3 30  ? 157.739 149.738 119.035 1.00 61.19  ? 27  PHE   H CB  1 
ATOM   3064 C CG  . PHE   C 3 30  ? 157.100 148.689 118.162 1.00 58.91  ? 27  PHE   H CG  1 
ATOM   3065 C CD1 . PHE   C 3 30  ? 157.831 148.034 117.186 1.00 60.45  ? 27  PHE   H CD1 1 
ATOM   3066 C CD2 . PHE   C 3 30  ? 155.757 148.389 118.296 1.00 53.60  ? 27  PHE   H CD2 1 
ATOM   3067 C CE1 . PHE   C 3 30  ? 157.241 147.082 116.381 1.00 58.57  ? 27  PHE   H CE1 1 
ATOM   3068 C CE2 . PHE   C 3 30  ? 155.161 147.436 117.497 1.00 51.46  ? 27  PHE   H CE2 1 
ATOM   3069 C CZ  . PHE   C 3 30  ? 155.903 146.785 116.536 1.00 54.23  ? 27  PHE   H CZ  1 
ATOM   3070 N N   . ASN   C 3 31  ? 157.029 149.153 121.904 1.00 67.57  ? 28  ASN   H N   1 
ATOM   3071 C CA  . ASN   C 3 31  ? 156.142 148.573 122.907 1.00 65.22  ? 28  ASN   H CA  1 
ATOM   3072 C C   . ASN   C 3 31  ? 154.984 147.853 122.221 1.00 63.39  ? 28  ASN   H C   1 
ATOM   3073 O O   . ASN   C 3 31  ? 154.535 148.266 121.148 1.00 63.21  ? 28  ASN   H O   1 
ATOM   3074 C CB  . ASN   C 3 31  ? 155.660 149.659 123.873 1.00 57.07  ? 28  ASN   H CB  1 
ATOM   3075 C CG  . ASN   C 3 31  ? 154.855 150.764 123.191 1.00 57.59  ? 28  ASN   H CG  1 
ATOM   3076 O OD1 . ASN   C 3 31  ? 153.965 150.513 122.383 1.00 53.14  ? 28  ASN   H OD1 1 
ATOM   3077 N ND2 . ASN   C 3 31  ? 155.188 152.008 123.518 1.00 59.80  ? 28  ASN   H ND2 1 
ATOM   3078 N N   . PHE   C 3 32  ? 154.530 146.749 122.819 1.00 57.38  ? 29  PHE   H N   1 
ATOM   3079 C CA  . PHE   C 3 32  ? 153.483 145.953 122.186 1.00 57.42  ? 29  PHE   H CA  1 
ATOM   3080 C C   . PHE   C 3 32  ? 152.100 146.298 122.724 1.00 55.10  ? 29  PHE   H C   1 
ATOM   3081 O O   . PHE   C 3 32  ? 151.094 146.056 122.047 1.00 54.21  ? 29  PHE   H O   1 
ATOM   3082 C CB  . PHE   C 3 32  ? 153.768 144.464 122.383 1.00 63.94  ? 29  PHE   H CB  1 
ATOM   3083 C CG  . PHE   C 3 32  ? 153.027 143.574 121.428 1.00 68.70  ? 29  PHE   H CG  1 
ATOM   3084 C CD1 . PHE   C 3 32  ? 153.483 143.398 120.133 1.00 62.68  ? 29  PHE   H CD1 1 
ATOM   3085 C CD2 . PHE   C 3 32  ? 151.870 142.922 121.821 1.00 70.23  ? 29  PHE   H CD2 1 
ATOM   3086 C CE1 . PHE   C 3 32  ? 152.804 142.582 119.251 1.00 59.95  ? 29  PHE   H CE1 1 
ATOM   3087 C CE2 . PHE   C 3 32  ? 151.185 142.105 120.941 1.00 63.35  ? 29  PHE   H CE2 1 
ATOM   3088 C CZ  . PHE   C 3 32  ? 151.653 141.936 119.654 1.00 60.03  ? 29  PHE   H CZ  1 
ATOM   3089 N N   . SER   C 3 33  ? 152.027 146.855 123.934 1.00 54.99  ? 30  SER   H N   1 
ATOM   3090 C CA  . SER   C 3 33  ? 150.730 147.086 124.562 1.00 52.25  ? 30  SER   H CA  1 
ATOM   3091 C C   . SER   C 3 33  ? 149.952 148.187 123.853 1.00 44.43  ? 30  SER   H C   1 
ATOM   3092 O O   . SER   C 3 33  ? 148.753 148.039 123.592 1.00 41.83  ? 30  SER   H O   1 
ATOM   3093 C CB  . SER   C 3 33  ? 150.920 147.430 126.040 1.00 52.52  ? 30  SER   H CB  1 
ATOM   3094 N N   . TYR   C 3 34  ? 150.616 149.292 123.525 1.00 43.92  ? 31  TYR   H N   1 
ATOM   3095 C CA  . TYR   C 3 34  ? 149.960 150.468 122.969 1.00 47.54  ? 31  TYR   H CA  1 
ATOM   3096 C C   . TYR   C 3 34  ? 149.693 150.353 121.473 1.00 49.73  ? 31  TYR   H C   1 
ATOM   3097 O O   . TYR   C 3 34  ? 149.424 151.369 120.825 1.00 48.32  ? 31  TYR   H O   1 
ATOM   3098 C CB  . TYR   C 3 34  ? 150.802 151.716 123.240 1.00 51.74  ? 31  TYR   H CB  1 
ATOM   3099 C CG  . TYR   C 3 34  ? 151.185 151.912 124.690 1.00 54.85  ? 31  TYR   H CG  1 
ATOM   3100 C CD1 . TYR   C 3 34  ? 150.304 151.593 125.715 1.00 55.46  ? 31  TYR   H CD1 1 
ATOM   3101 C CD2 . TYR   C 3 34  ? 152.435 152.410 125.033 1.00 52.09  ? 31  TYR   H CD2 1 
ATOM   3102 C CE1 . TYR   C 3 34  ? 150.656 151.769 127.040 1.00 59.97  ? 31  TYR   H CE1 1 
ATOM   3103 C CE2 . TYR   C 3 34  ? 152.796 152.589 126.353 1.00 50.11  ? 31  TYR   H CE2 1 
ATOM   3104 C CZ  . TYR   C 3 34  ? 151.905 152.268 127.353 1.00 57.08  ? 31  TYR   H CZ  1 
ATOM   3105 O OH  . TYR   C 3 34  ? 152.264 152.447 128.669 1.00 60.68  ? 31  TYR   H OH  1 
ATOM   3106 N N   . TYR   C 3 35  ? 149.760 149.148 120.914 1.00 47.32  ? 32  TYR   H N   1 
ATOM   3107 C CA  . TYR   C 3 35  ? 149.571 148.931 119.490 1.00 35.88  ? 32  TYR   H CA  1 
ATOM   3108 C C   . TYR   C 3 35  ? 148.744 147.678 119.256 1.00 36.02  ? 32  TYR   H C   1 
ATOM   3109 O O   . TYR   C 3 35  ? 148.374 146.962 120.189 1.00 46.00  ? 32  TYR   H O   1 
ATOM   3110 C CB  . TYR   C 3 35  ? 150.908 148.793 118.754 1.00 36.58  ? 32  TYR   H CB  1 
ATOM   3111 C CG  . TYR   C 3 35  ? 151.740 150.048 118.723 1.00 45.13  ? 32  TYR   H CG  1 
ATOM   3112 C CD1 . TYR   C 3 35  ? 151.239 151.220 118.182 1.00 44.50  ? 32  TYR   H CD1 1 
ATOM   3113 C CD2 . TYR   C 3 35  ? 153.031 150.057 119.220 1.00 48.81  ? 32  TYR   H CD2 1 
ATOM   3114 C CE1 . TYR   C 3 35  ? 152.000 152.364 118.141 1.00 43.34  ? 32  TYR   H CE1 1 
ATOM   3115 C CE2 . TYR   C 3 35  ? 153.801 151.198 119.186 1.00 50.33  ? 32  TYR   H CE2 1 
ATOM   3116 C CZ  . TYR   C 3 35  ? 153.279 152.350 118.649 1.00 45.71  ? 32  TYR   H CZ  1 
ATOM   3117 O OH  . TYR   C 3 35  ? 154.043 153.493 118.613 1.00 48.44  ? 32  TYR   H OH  1 
ATOM   3118 N N   . SER   C 3 36  ? 148.455 147.430 117.984 1.00 31.50  ? 33  SER   H N   1 
ATOM   3119 C CA  . SER   C 3 36  ? 147.877 146.179 117.528 1.00 29.69  ? 33  SER   H CA  1 
ATOM   3120 C C   . SER   C 3 36  ? 148.673 145.668 116.336 1.00 24.96  ? 33  SER   H C   1 
ATOM   3121 O O   . SER   C 3 36  ? 149.259 146.449 115.581 1.00 29.42  ? 33  SER   H O   1 
ATOM   3122 C CB  . SER   C 3 36  ? 146.405 146.349 117.141 1.00 33.11  ? 33  SER   H CB  1 
ATOM   3123 O OG  . SER   C 3 36  ? 146.271 147.138 115.971 1.00 31.83  ? 33  SER   H OG  1 
ATOM   3124 N N   . ILE   C 3 37  ? 148.697 144.350 116.175 1.00 22.75  ? 34  ILE   H N   1 
ATOM   3125 C CA  . ILE   C 3 37  ? 149.335 143.706 115.035 1.00 22.96  ? 34  ILE   H CA  1 
ATOM   3126 C C   . ILE   C 3 37  ? 148.241 143.122 114.157 1.00 26.00  ? 34  ILE   H C   1 
ATOM   3127 O O   . ILE   C 3 37  ? 147.391 142.360 114.634 1.00 30.52  ? 34  ILE   H O   1 
ATOM   3128 C CB  . ILE   C 3 37  ? 150.332 142.622 115.474 1.00 23.96  ? 34  ILE   H CB  1 
ATOM   3129 C CG1 . ILE   C 3 37  ? 151.595 143.266 116.042 1.00 27.51  ? 34  ILE   H CG1 1 
ATOM   3130 C CG2 . ILE   C 3 37  ? 150.686 141.721 114.304 1.00 22.24  ? 34  ILE   H CG2 1 
ATOM   3131 C CD1 . ILE   C 3 37  ? 152.357 144.089 115.038 1.00 30.29  ? 34  ILE   H CD1 1 
ATOM   3132 N N   . HIS   C 3 38  ? 148.261 143.482 112.879 1.00 23.92  ? 35  HIS   H N   1 
ATOM   3133 C CA  . HIS   C 3 38  ? 147.254 143.064 111.920 1.00 23.33  ? 35  HIS   H CA  1 
ATOM   3134 C C   . HIS   C 3 38  ? 147.828 141.986 111.014 1.00 23.60  ? 35  HIS   H C   1 
ATOM   3135 O O   . HIS   C 3 38  ? 149.042 141.794 110.949 1.00 23.95  ? 35  HIS   H O   1 
ATOM   3136 C CB  . HIS   C 3 38  ? 146.777 144.247 111.077 1.00 20.17  ? 35  HIS   H CB  1 
ATOM   3137 C CG  . HIS   C 3 38  ? 146.163 145.350 111.878 1.00 21.50  ? 35  HIS   H CG  1 
ATOM   3138 N ND1 . HIS   C 3 38  ? 144.821 145.655 111.815 1.00 23.65  ? 35  HIS   H ND1 1 
ATOM   3139 C CD2 . HIS   C 3 38  ? 146.706 146.220 112.761 1.00 25.37  ? 35  HIS   H CD2 1 
ATOM   3140 C CE1 . HIS   C 3 38  ? 144.563 146.666 112.626 1.00 26.68  ? 35  HIS   H CE1 1 
ATOM   3141 N NE2 . HIS   C 3 38  ? 145.691 147.027 113.212 1.00 25.60  ? 35  HIS   H NE2 1 
ATOM   3142 N N   . TRP   C 3 39  ? 146.940 141.257 110.344 1.00 24.01  ? 36  TRP   H N   1 
ATOM   3143 C CA  . TRP   C 3 39  ? 147.323 140.325 109.292 1.00 22.89  ? 36  TRP   H CA  1 
ATOM   3144 C C   . TRP   C 3 39  ? 146.609 140.733 108.014 1.00 21.80  ? 36  TRP   H C   1 
ATOM   3145 O O   . TRP   C 3 39  ? 145.382 140.873 108.002 1.00 25.08  ? 36  TRP   H O   1 
ATOM   3146 C CB  . TRP   C 3 39  ? 146.988 138.879 109.669 1.00 31.20  ? 36  TRP   H CB  1 
ATOM   3147 C CG  . TRP   C 3 39  ? 147.927 138.292 110.684 1.00 38.85  ? 36  TRP   H CG  1 
ATOM   3148 C CD1 . TRP   C 3 39  ? 147.729 138.206 112.031 1.00 37.31  ? 36  TRP   H CD1 1 
ATOM   3149 C CD2 . TRP   C 3 39  ? 149.209 137.703 110.430 1.00 35.97  ? 36  TRP   H CD2 1 
ATOM   3150 N NE1 . TRP   C 3 39  ? 148.810 137.607 112.631 1.00 39.08  ? 36  TRP   H NE1 1 
ATOM   3151 C CE2 . TRP   C 3 39  ? 149.732 137.289 111.670 1.00 37.92  ? 36  TRP   H CE2 1 
ATOM   3152 C CE3 . TRP   C 3 39  ? 149.966 137.489 109.274 1.00 31.24  ? 36  TRP   H CE3 1 
ATOM   3153 C CZ2 . TRP   C 3 39  ? 150.975 136.673 111.787 1.00 41.50  ? 36  TRP   H CZ2 1 
ATOM   3154 C CZ3 . TRP   C 3 39  ? 151.200 136.877 109.394 1.00 32.95  ? 36  TRP   H CZ3 1 
ATOM   3155 C CH2 . TRP   C 3 39  ? 151.692 136.477 110.639 1.00 38.52  ? 36  TRP   H CH2 1 
ATOM   3156 N N   . VAL   C 3 40  ? 147.377 140.935 106.947 1.00 20.24  ? 37  VAL   H N   1 
ATOM   3157 C CA  . VAL   C 3 40  ? 146.840 141.315 105.647 1.00 17.32  ? 37  VAL   H CA  1 
ATOM   3158 C C   . VAL   C 3 40  ? 147.247 140.247 104.644 1.00 18.89  ? 37  VAL   H C   1 
ATOM   3159 O O   . VAL   C 3 40  ? 148.432 139.913 104.531 1.00 20.51  ? 37  VAL   H O   1 
ATOM   3160 C CB  . VAL   C 3 40  ? 147.334 142.705 105.207 1.00 16.21  ? 37  VAL   H CB  1 
ATOM   3161 C CG1 . VAL   C 3 40  ? 146.821 143.032 103.821 1.00 19.14  ? 37  VAL   H CG1 1 
ATOM   3162 C CG2 . VAL   C 3 40  ? 146.886 143.764 106.200 1.00 16.09  ? 37  VAL   H CG2 1 
ATOM   3163 N N   . ARG   C 3 41  ? 146.266 139.715 103.922 1.00 18.57  ? 38  ARG   H N   1 
ATOM   3164 C CA  . ARG   C 3 41  ? 146.481 138.639 102.968 1.00 17.83  ? 38  ARG   H CA  1 
ATOM   3165 C C   . ARG   C 3 41  ? 146.411 139.197 101.555 1.00 19.59  ? 38  ARG   H C   1 
ATOM   3166 O O   . ARG   C 3 41  ? 145.642 140.126 101.285 1.00 24.11  ? 38  ARG   H O   1 
ATOM   3167 C CB  . ARG   C 3 41  ? 145.448 137.526 103.159 1.00 24.06  ? 38  ARG   H CB  1 
ATOM   3168 C CG  . ARG   C 3 41  ? 144.092 137.813 102.538 1.00 27.74  ? 38  ARG   H CG  1 
ATOM   3169 C CD  . ARG   C 3 41  ? 143.054 136.787 102.951 1.00 33.58  ? 38  ARG   H CD  1 
ATOM   3170 N NE  . ARG   C 3 41  ? 143.373 135.462 102.438 1.00 24.03  ? 38  ARG   H NE  1 
ATOM   3171 C CZ  . ARG   C 3 41  ? 143.456 134.373 103.187 1.00 22.90  ? 38  ARG   H CZ  1 
ATOM   3172 N NH1 . ARG   C 3 41  ? 143.229 134.410 104.489 1.00 24.94  ? 38  ARG   H NH1 1 
ATOM   3173 N NH2 . ARG   C 3 41  ? 143.782 133.217 102.618 1.00 28.34  ? 38  ARG   H NH2 1 
ATOM   3174 N N   . GLN   C 3 42  ? 147.236 138.650 100.666 1.00 22.88  ? 39  GLN   H N   1 
ATOM   3175 C CA  . GLN   C 3 42  ? 147.218 139.000 99.250  1.00 23.19  ? 39  GLN   H CA  1 
ATOM   3176 C C   . GLN   C 3 42  ? 147.270 137.699 98.460  1.00 24.35  ? 39  GLN   H C   1 
ATOM   3177 O O   . GLN   C 3 42  ? 148.264 136.966 98.522  1.00 27.07  ? 39  GLN   H O   1 
ATOM   3178 C CB  . GLN   C 3 42  ? 148.378 139.934 98.892  1.00 22.86  ? 39  GLN   H CB  1 
ATOM   3179 C CG  . GLN   C 3 42  ? 149.022 139.684 97.534  1.00 23.70  ? 39  GLN   H CG  1 
ATOM   3180 C CD  . GLN   C 3 42  ? 149.812 140.876 97.037  1.00 29.69  ? 39  GLN   H CD  1 
ATOM   3181 O OE1 . GLN   C 3 42  ? 151.038 140.829 96.951  1.00 34.66  ? 39  GLN   H OE1 1 
ATOM   3182 N NE2 . GLN   C 3 42  ? 149.112 141.955 96.708  1.00 24.14  ? 39  GLN   H NE2 1 
ATOM   3183 N N   . ALA   C 3 43  ? 146.177 137.381 97.774  1.00 25.69  ? 40  ALA   H N   1 
ATOM   3184 C CA  . ALA   C 3 43  ? 146.165 136.218 96.907  1.00 24.47  ? 40  ALA   H CA  1 
ATOM   3185 C C   . ALA   C 3 43  ? 147.079 136.456 95.706  1.00 22.28  ? 40  ALA   H C   1 
ATOM   3186 O O   . ALA   C 3 43  ? 147.239 137.594 95.258  1.00 26.06  ? 40  ALA   H O   1 
ATOM   3187 C CB  . ALA   C 3 43  ? 144.746 135.915 96.436  1.00 24.75  ? 40  ALA   H CB  1 
ATOM   3188 N N   . PRO   C 3 44  ? 147.705 135.406 95.178  1.00 19.09  ? 41  PRO   H N   1 
ATOM   3189 C CA  . PRO   C 3 44  ? 148.554 135.584 93.994  1.00 18.87  ? 41  PRO   H CA  1 
ATOM   3190 C C   . PRO   C 3 44  ? 147.742 136.122 92.825  1.00 23.49  ? 41  PRO   H C   1 
ATOM   3191 O O   . PRO   C 3 44  ? 146.737 135.535 92.420  1.00 26.97  ? 41  PRO   H O   1 
ATOM   3192 C CB  . PRO   C 3 44  ? 149.089 134.173 93.720  1.00 17.89  ? 41  PRO   H CB  1 
ATOM   3193 C CG  . PRO   C 3 44  ? 148.168 133.255 94.445  1.00 19.30  ? 41  PRO   H CG  1 
ATOM   3194 C CD  . PRO   C 3 44  ? 147.680 134.008 95.638  1.00 22.74  ? 41  PRO   H CD  1 
ATOM   3195 N N   . GLY   C 3 45  ? 148.191 137.251 92.284  1.00 25.83  ? 42  GLY   H N   1 
ATOM   3196 C CA  . GLY   C 3 45  ? 147.425 137.944 91.267  1.00 19.33  ? 42  GLY   H CA  1 
ATOM   3197 C C   . GLY   C 3 45  ? 146.125 138.537 91.763  1.00 18.72  ? 42  GLY   H C   1 
ATOM   3198 O O   . GLY   C 3 45  ? 145.115 138.476 91.055  1.00 19.84  ? 42  GLY   H O   1 
ATOM   3199 N N   . LYS   C 3 46  ? 146.120 139.108 92.965  1.00 20.26  ? 43  LYS   H N   1 
ATOM   3200 C CA  . LYS   C 3 46  ? 144.920 139.714 93.522  1.00 22.38  ? 43  LYS   H CA  1 
ATOM   3201 C C   . LYS   C 3 46  ? 145.326 140.792 94.518  1.00 22.71  ? 43  LYS   H C   1 
ATOM   3202 O O   . LYS   C 3 46  ? 146.497 140.923 94.883  1.00 23.28  ? 43  LYS   H O   1 
ATOM   3203 C CB  . LYS   C 3 46  ? 144.016 138.668 94.182  1.00 20.13  ? 43  LYS   H CB  1 
ATOM   3204 N N   . GLY   C 3 47  ? 144.336 141.564 94.959  1.00 20.46  ? 44  GLY   H N   1 
ATOM   3205 C CA  . GLY   C 3 47  ? 144.598 142.713 95.796  1.00 18.44  ? 44  GLY   H CA  1 
ATOM   3206 C C   . GLY   C 3 47  ? 144.817 142.367 97.256  1.00 18.52  ? 44  GLY   H C   1 
ATOM   3207 O O   . GLY   C 3 47  ? 144.923 141.207 97.649  1.00 21.41  ? 44  GLY   H O   1 
ATOM   3208 N N   . LEU   C 3 48  ? 144.895 143.420 98.066  1.00 14.11  ? 45  LEU   H N   1 
ATOM   3209 C CA  . LEU   C 3 48  ? 145.084 143.264 99.500  1.00 11.69  ? 45  LEU   H CA  1 
ATOM   3210 C C   . LEU   C 3 48  ? 143.755 142.986 100.186 1.00 13.44  ? 45  LEU   H C   1 
ATOM   3211 O O   . LEU   C 3 48  ? 142.744 143.632 99.901  1.00 14.34  ? 45  LEU   H O   1 
ATOM   3212 C CB  . LEU   C 3 48  ? 145.707 144.525 100.092 1.00 12.49  ? 45  LEU   H CB  1 
ATOM   3213 C CG  . LEU   C 3 48  ? 147.206 144.744 99.906  1.00 13.71  ? 45  LEU   H CG  1 
ATOM   3214 C CD1 . LEU   C 3 48  ? 147.652 145.919 100.752 1.00 9.56   ? 45  LEU   H CD1 1 
ATOM   3215 C CD2 . LEU   C 3 48  ? 147.986 143.495 100.255 1.00 12.82  ? 45  LEU   H CD2 1 
ATOM   3216 N N   . GLU   C 3 49  ? 143.760 142.017 101.098 1.00 18.93  ? 46  GLU   H N   1 
ATOM   3217 C CA  . GLU   C 3 49  ? 142.582 141.708 101.894 1.00 21.26  ? 46  GLU   H CA  1 
ATOM   3218 C C   . GLU   C 3 49  ? 142.980 141.611 103.358 1.00 20.43  ? 46  GLU   H C   1 
ATOM   3219 O O   . GLU   C 3 49  ? 143.960 140.944 103.702 1.00 19.23  ? 46  GLU   H O   1 
ATOM   3220 C CB  . GLU   C 3 49  ? 141.916 140.401 101.437 1.00 23.23  ? 46  GLU   H CB  1 
ATOM   3221 C CG  . GLU   C 3 49  ? 141.526 140.350 99.957  1.00 25.87  ? 46  GLU   H CG  1 
ATOM   3222 C CD  . GLU   C 3 49  ? 140.345 141.242 99.593  1.00 25.58  ? 46  GLU   H CD  1 
ATOM   3223 O OE1 . GLU   C 3 49  ? 139.750 141.013 98.519  1.00 24.87  ? 46  GLU   H OE1 1 
ATOM   3224 O OE2 . GLU   C 3 49  ? 140.001 142.161 100.365 1.00 21.31  ? 46  GLU   H OE2 1 
ATOM   3225 N N   . TRP   C 3 50  ? 142.213 142.281 104.213 1.00 18.54  ? 47  TRP   H N   1 
ATOM   3226 C CA  . TRP   C 3 50  ? 142.449 142.290 105.650 1.00 22.02  ? 47  TRP   H CA  1 
ATOM   3227 C C   . TRP   C 3 50  ? 141.598 141.212 106.304 1.00 31.66  ? 47  TRP   H C   1 
ATOM   3228 O O   . TRP   C 3 50  ? 140.397 141.114 106.031 1.00 35.76  ? 47  TRP   H O   1 
ATOM   3229 C CB  . TRP   C 3 50  ? 142.121 143.661 106.243 1.00 23.11  ? 47  TRP   H CB  1 
ATOM   3230 C CG  . TRP   C 3 50  ? 142.258 143.723 107.731 1.00 24.13  ? 47  TRP   H CG  1 
ATOM   3231 C CD1 . TRP   C 3 50  ? 143.410 143.869 108.442 1.00 24.14  ? 47  TRP   H CD1 1 
ATOM   3232 C CD2 . TRP   C 3 50  ? 141.199 143.639 108.692 1.00 27.57  ? 47  TRP   H CD2 1 
ATOM   3233 N NE1 . TRP   C 3 50  ? 143.136 143.883 109.788 1.00 26.16  ? 47  TRP   H NE1 1 
ATOM   3234 C CE2 . TRP   C 3 50  ? 141.786 143.744 109.968 1.00 29.46  ? 47  TRP   H CE2 1 
ATOM   3235 C CE3 . TRP   C 3 50  ? 139.813 143.488 108.598 1.00 29.28  ? 47  TRP   H CE3 1 
ATOM   3236 C CZ2 . TRP   C 3 50  ? 141.035 143.700 111.139 1.00 32.58  ? 47  TRP   H CZ2 1 
ATOM   3237 C CZ3 . TRP   C 3 50  ? 139.070 143.444 109.761 1.00 29.47  ? 47  TRP   H CZ3 1 
ATOM   3238 C CH2 . TRP   C 3 50  ? 139.681 143.550 111.014 1.00 32.14  ? 47  TRP   H CH2 1 
ATOM   3239 N N   . VAL   C 3 51  ? 142.220 140.403 107.161 1.00 32.92  ? 48  VAL   H N   1 
ATOM   3240 C CA  . VAL   C 3 51  ? 141.517 139.284 107.779 1.00 30.34  ? 48  VAL   H CA  1 
ATOM   3241 C C   . VAL   C 3 51  ? 141.213 139.566 109.247 1.00 34.64  ? 48  VAL   H C   1 
ATOM   3242 O O   . VAL   C 3 51  ? 140.078 139.374 109.699 1.00 41.42  ? 48  VAL   H O   1 
ATOM   3243 C CB  . VAL   C 3 51  ? 142.308 137.971 107.613 1.00 28.88  ? 48  VAL   H CB  1 
ATOM   3244 C CG1 . VAL   C 3 51  ? 143.750 138.129 108.068 1.00 29.28  ? 48  VAL   H CG1 1 
ATOM   3245 C CG2 . VAL   C 3 51  ? 141.627 136.853 108.376 1.00 37.41  ? 48  VAL   H CG2 1 
ATOM   3246 N N   . ALA   C 3 52  ? 142.206 140.035 110.001 1.00 32.31  ? 49  ALA   H N   1 
ATOM   3247 C CA  . ALA   C 3 52  ? 142.035 140.215 111.438 1.00 35.97  ? 49  ALA   H CA  1 
ATOM   3248 C C   . ALA   C 3 52  ? 143.147 141.111 111.965 1.00 30.89  ? 49  ALA   H C   1 
ATOM   3249 O O   . ALA   C 3 52  ? 143.954 141.652 111.204 1.00 28.90  ? 49  ALA   H O   1 
ATOM   3250 C CB  . ALA   C 3 52  ? 142.027 138.873 112.175 1.00 40.60  ? 49  ALA   H CB  1 
ATOM   3251 N N   . TYR   C 3 53  ? 143.172 141.260 113.290 1.00 30.10  ? 50  TYR   H N   1 
ATOM   3252 C CA  . TYR   C 3 53  ? 144.146 142.087 113.985 1.00 32.56  ? 50  TYR   H CA  1 
ATOM   3253 C C   . TYR   C 3 53  ? 144.363 141.560 115.395 1.00 37.56  ? 50  TYR   H C   1 
ATOM   3254 O O   . TYR   C 3 53  ? 143.549 140.796 115.921 1.00 44.05  ? 50  TYR   H O   1 
ATOM   3255 C CB  . TYR   C 3 53  ? 143.699 143.551 114.026 1.00 33.47  ? 50  TYR   H CB  1 
ATOM   3256 C CG  . TYR   C 3 53  ? 142.629 143.867 115.048 1.00 32.91  ? 50  TYR   H CG  1 
ATOM   3257 C CD1 . TYR   C 3 53  ? 141.286 143.683 114.750 1.00 35.93  ? 50  TYR   H CD1 1 
ATOM   3258 C CD2 . TYR   C 3 53  ? 142.957 144.382 116.295 1.00 30.33  ? 50  TYR   H CD2 1 
ATOM   3259 C CE1 . TYR   C 3 53  ? 140.302 143.985 115.668 1.00 40.19  ? 50  TYR   H CE1 1 
ATOM   3260 C CE2 . TYR   C 3 53  ? 141.978 144.686 117.221 1.00 35.23  ? 50  TYR   H CE2 1 
ATOM   3261 C CZ  . TYR   C 3 53  ? 140.652 144.486 116.901 1.00 41.10  ? 50  TYR   H CZ  1 
ATOM   3262 O OH  . TYR   C 3 53  ? 139.672 144.787 117.817 1.00 47.91  ? 50  TYR   H OH  1 
ATOM   3263 N N   . ILE   C 3 54  ? 145.471 141.973 116.002 1.00 32.64  ? 51  ILE   H N   1 
ATOM   3264 C CA  . ILE   C 3 54  ? 145.802 141.542 117.357 1.00 33.91  ? 51  ILE   H CA  1 
ATOM   3265 C C   . ILE   C 3 54  ? 146.602 142.613 118.088 1.00 36.53  ? 51  ILE   H C   1 
ATOM   3266 O O   . ILE   C 3 54  ? 147.141 142.369 119.167 1.00 34.40  ? 51  ILE   H O   1 
ATOM   3267 C CB  . ILE   C 3 54  ? 146.571 140.212 117.343 1.00 35.65  ? 51  ILE   H CB  1 
ATOM   3268 N N   . TYR   C 3 60  ? 139.522 142.731 122.420 1.00 47.52  ? 56  TYR   H N   1 
ATOM   3269 C CA  . TYR   C 3 60  ? 139.543 143.565 121.224 1.00 48.26  ? 56  TYR   H CA  1 
ATOM   3270 C C   . TYR   C 3 60  ? 140.018 142.766 120.018 1.00 47.07  ? 56  TYR   H C   1 
ATOM   3271 O O   . TYR   C 3 60  ? 141.204 142.771 119.689 1.00 46.69  ? 56  TYR   H O   1 
ATOM   3272 C CB  . TYR   C 3 60  ? 140.444 144.782 121.432 1.00 46.91  ? 56  TYR   H CB  1 
ATOM   3273 C CG  . TYR   C 3 60  ? 140.281 145.441 122.782 1.00 52.42  ? 56  TYR   H CG  1 
ATOM   3274 C CD1 . TYR   C 3 60  ? 139.026 145.802 123.253 1.00 55.11  ? 56  TYR   H CD1 1 
ATOM   3275 C CD2 . TYR   C 3 60  ? 141.383 145.701 123.585 1.00 54.38  ? 56  TYR   H CD2 1 
ATOM   3276 C CE1 . TYR   C 3 60  ? 138.873 146.403 124.488 1.00 59.14  ? 56  TYR   H CE1 1 
ATOM   3277 C CE2 . TYR   C 3 60  ? 141.240 146.301 124.821 1.00 56.83  ? 56  TYR   H CE2 1 
ATOM   3278 C CZ  . TYR   C 3 60  ? 139.983 146.651 125.267 1.00 61.46  ? 56  TYR   H CZ  1 
ATOM   3279 O OH  . TYR   C 3 60  ? 139.836 147.250 126.496 1.00 66.20  ? 56  TYR   H OH  1 
ATOM   3280 N N   . THR   C 3 61  ? 139.087 142.075 119.362 1.00 44.21  ? 57  THR   H N   1 
ATOM   3281 C CA  . THR   C 3 61  ? 139.410 141.254 118.205 1.00 46.09  ? 57  THR   H CA  1 
ATOM   3282 C C   . THR   C 3 61  ? 138.262 141.298 117.209 1.00 50.81  ? 57  THR   H C   1 
ATOM   3283 O O   . THR   C 3 61  ? 137.094 141.381 117.599 1.00 56.90  ? 57  THR   H O   1 
ATOM   3284 C CB  . THR   C 3 61  ? 139.695 139.803 118.615 1.00 51.97  ? 57  THR   H CB  1 
ATOM   3285 O OG1 . THR   C 3 61  ? 140.581 139.789 119.741 1.00 56.44  ? 57  THR   H OG1 1 
ATOM   3286 C CG2 . THR   C 3 61  ? 140.341 139.047 117.474 1.00 49.49  ? 57  THR   H CG2 1 
ATOM   3287 N N   . SER   C 3 62  ? 138.603 141.245 115.922 1.00 46.95  ? 58  SER   H N   1 
ATOM   3288 C CA  . SER   C 3 62  ? 137.613 141.223 114.856 1.00 44.17  ? 58  SER   H CA  1 
ATOM   3289 C C   . SER   C 3 62  ? 138.124 140.334 113.732 1.00 49.37  ? 58  SER   H C   1 
ATOM   3290 O O   . SER   C 3 62  ? 139.331 140.151 113.558 1.00 49.29  ? 58  SER   H O   1 
ATOM   3291 C CB  . SER   C 3 62  ? 137.311 142.632 114.334 1.00 41.10  ? 58  SER   H CB  1 
ATOM   3292 N N   . TYR   C 3 63  ? 137.185 139.779 112.968 1.00 51.36  ? 59  TYR   H N   1 
ATOM   3293 C CA  . TYR   C 3 63  ? 137.506 138.880 111.870 1.00 52.42  ? 59  TYR   H CA  1 
ATOM   3294 C C   . TYR   C 3 63  ? 136.724 139.286 110.630 1.00 55.57  ? 59  TYR   H C   1 
ATOM   3295 O O   . TYR   C 3 63  ? 135.636 139.861 110.723 1.00 56.76  ? 59  TYR   H O   1 
ATOM   3296 C CB  . TYR   C 3 63  ? 137.191 137.419 112.217 1.00 59.40  ? 59  TYR   H CB  1 
ATOM   3297 C CG  . TYR   C 3 63  ? 137.949 136.882 113.408 1.00 61.95  ? 59  TYR   H CG  1 
ATOM   3298 C CD1 . TYR   C 3 63  ? 139.282 136.511 113.296 1.00 60.26  ? 59  TYR   H CD1 1 
ATOM   3299 C CD2 . TYR   C 3 63  ? 137.332 136.741 114.644 1.00 63.47  ? 59  TYR   H CD2 1 
ATOM   3300 C CE1 . TYR   C 3 63  ? 139.978 136.016 114.379 1.00 62.03  ? 59  TYR   H CE1 1 
ATOM   3301 C CE2 . TYR   C 3 63  ? 138.021 136.248 115.734 1.00 62.59  ? 59  TYR   H CE2 1 
ATOM   3302 C CZ  . TYR   C 3 63  ? 139.344 135.888 115.596 1.00 64.92  ? 59  TYR   H CZ  1 
ATOM   3303 O OH  . TYR   C 3 63  ? 140.037 135.397 116.678 1.00 71.06  ? 59  TYR   H OH  1 
ATOM   3304 N N   . ALA   C 3 64  ? 137.291 138.976 109.468 1.00 56.08  ? 60  ALA   H N   1 
ATOM   3305 C CA  . ALA   C 3 64  ? 136.613 139.245 108.209 1.00 56.34  ? 60  ALA   H CA  1 
ATOM   3306 C C   . ALA   C 3 64  ? 135.499 138.233 107.972 1.00 57.34  ? 60  ALA   H C   1 
ATOM   3307 O O   . ALA   C 3 64  ? 135.641 137.039 108.250 1.00 54.48  ? 60  ALA   H O   1 
ATOM   3308 C CB  . ALA   C 3 64  ? 137.607 139.213 107.049 1.00 53.25  ? 60  ALA   H CB  1 
ATOM   3309 N N   . ASP   C 3 65  ? 134.380 138.723 107.447 1.00 58.76  ? 61  ASP   H N   1 
ATOM   3310 C CA  . ASP   C 3 65  ? 133.224 137.875 107.179 1.00 60.48  ? 61  ASP   H CA  1 
ATOM   3311 C C   . ASP   C 3 65  ? 133.508 136.899 106.043 1.00 65.36  ? 61  ASP   H C   1 
ATOM   3312 O O   . ASP   C 3 65  ? 133.755 135.716 106.277 1.00 64.07  ? 61  ASP   H O   1 
ATOM   3313 C CB  . ASP   C 3 65  ? 132.000 138.729 106.843 1.00 57.25  ? 61  ASP   H CB  1 
ATOM   3314 N N   . VAL   C 3 67  ? 135.799 134.694 106.788 1.00 55.23  ? 63  VAL   H N   1 
ATOM   3315 C CA  . VAL   C 3 67  ? 136.865 134.048 107.542 1.00 60.05  ? 63  VAL   H CA  1 
ATOM   3316 C C   . VAL   C 3 67  ? 136.458 133.888 109.002 1.00 68.08  ? 63  VAL   H C   1 
ATOM   3317 O O   . VAL   C 3 67  ? 137.216 133.354 109.810 1.00 65.22  ? 63  VAL   H O   1 
ATOM   3318 C CB  . VAL   C 3 67  ? 138.180 134.835 107.427 1.00 54.03  ? 63  VAL   H CB  1 
ATOM   3319 N N   . LYS   C 3 68  ? 135.256 134.355 109.333 1.00 71.97  ? 64  LYS   H N   1 
ATOM   3320 C CA  . LYS   C 3 68  ? 134.768 134.251 110.701 1.00 69.18  ? 64  LYS   H CA  1 
ATOM   3321 C C   . LYS   C 3 68  ? 134.503 132.796 111.066 1.00 65.13  ? 64  LYS   H C   1 
ATOM   3322 O O   . LYS   C 3 68  ? 134.029 132.007 110.244 1.00 62.58  ? 64  LYS   H O   1 
ATOM   3323 C CB  . LYS   C 3 68  ? 133.493 135.078 110.873 1.00 71.09  ? 64  LYS   H CB  1 
ATOM   3324 N N   . GLY   C 3 69  ? 134.812 132.445 112.307 1.00 68.88  ? 65  GLY   H N   1 
ATOM   3325 C CA  . GLY   C 3 69  ? 134.626 131.072 112.776 1.00 70.56  ? 65  GLY   H CA  1 
ATOM   3326 C C   . GLY   C 3 69  ? 135.743 130.113 112.435 1.00 70.25  ? 65  GLY   H C   1 
ATOM   3327 O O   . GLY   C 3 69  ? 136.265 129.429 113.320 1.00 70.91  ? 65  GLY   H O   1 
ATOM   3328 N N   . ARG   C 3 70  ? 136.124 130.042 111.158 1.00 71.35  ? 66  ARG   H N   1 
ATOM   3329 C CA  . ARG   C 3 70  ? 137.204 129.147 110.757 1.00 70.69  ? 66  ARG   H CA  1 
ATOM   3330 C C   . ARG   C 3 70  ? 138.561 129.658 111.223 1.00 69.93  ? 66  ARG   H C   1 
ATOM   3331 O O   . ARG   C 3 70  ? 139.500 128.870 111.379 1.00 66.73  ? 66  ARG   H O   1 
ATOM   3332 C CB  . ARG   C 3 70  ? 137.195 128.968 109.240 1.00 65.00  ? 66  ARG   H CB  1 
ATOM   3333 C CG  . ARG   C 3 70  ? 135.845 129.236 108.591 1.00 64.97  ? 66  ARG   H CG  1 
ATOM   3334 C CD  . ARG   C 3 70  ? 135.862 129.089 107.065 1.00 59.91  ? 66  ARG   H CD  1 
ATOM   3335 N NE  . ARG   C 3 70  ? 136.945 129.816 106.411 1.00 60.91  ? 66  ARG   H NE  1 
ATOM   3336 C CZ  . ARG   C 3 70  ? 138.136 129.305 106.127 1.00 61.51  ? 66  ARG   H CZ  1 
ATOM   3337 N NH1 . ARG   C 3 70  ? 138.435 128.048 106.411 1.00 65.90  ? 66  ARG   H NH1 1 
ATOM   3338 N NH2 . ARG   C 3 70  ? 139.048 130.072 105.536 1.00 54.98  ? 66  ARG   H NH2 1 
ATOM   3339 N N   . PHE   C 3 71  ? 138.686 130.962 111.444 1.00 68.08  ? 67  PHE   H N   1 
ATOM   3340 C CA  . PHE   C 3 71  ? 139.952 131.580 111.806 1.00 62.55  ? 67  PHE   H CA  1 
ATOM   3341 C C   . PHE   C 3 71  ? 140.052 131.765 113.315 1.00 68.81  ? 67  PHE   H C   1 
ATOM   3342 O O   . PHE   C 3 71  ? 139.043 131.843 114.020 1.00 72.30  ? 67  PHE   H O   1 
ATOM   3343 C CB  . PHE   C 3 71  ? 140.113 132.935 111.115 1.00 58.77  ? 67  PHE   H CB  1 
ATOM   3344 C CG  . PHE   C 3 71  ? 140.698 132.849 109.736 1.00 58.53  ? 67  PHE   H CG  1 
ATOM   3345 C CD1 . PHE   C 3 71  ? 140.071 132.112 108.747 1.00 62.08  ? 67  PHE   H CD1 1 
ATOM   3346 C CD2 . PHE   C 3 71  ? 141.873 133.511 109.427 1.00 47.19  ? 67  PHE   H CD2 1 
ATOM   3347 C CE1 . PHE   C 3 71  ? 140.605 132.035 107.477 1.00 51.30  ? 67  PHE   H CE1 1 
ATOM   3348 C CE2 . PHE   C 3 71  ? 142.410 133.439 108.159 1.00 40.62  ? 67  PHE   H CE2 1 
ATOM   3349 C CZ  . PHE   C 3 71  ? 141.776 132.700 107.183 1.00 39.41  ? 67  PHE   H CZ  1 
ATOM   3350 N N   . THR   C 3 72  ? 141.289 131.833 113.802 1.00 68.97  ? 68  THR   H N   1 
ATOM   3351 C CA  . THR   C 3 72  ? 141.576 132.112 115.201 1.00 70.97  ? 68  THR   H CA  1 
ATOM   3352 C C   . THR   C 3 72  ? 142.863 132.916 115.301 1.00 62.59  ? 68  THR   H C   1 
ATOM   3353 O O   . THR   C 3 72  ? 143.885 132.539 114.721 1.00 60.01  ? 68  THR   H O   1 
ATOM   3354 C CB  . THR   C 3 72  ? 141.704 130.818 116.019 1.00 71.83  ? 68  THR   H CB  1 
ATOM   3355 O OG1 . THR   C 3 72  ? 140.513 130.034 115.871 1.00 71.41  ? 68  THR   H OG1 1 
ATOM   3356 C CG2 . THR   C 3 72  ? 141.918 131.134 117.492 1.00 67.83  ? 68  THR   H CG2 1 
ATOM   3357 N N   . ILE   C 3 73  ? 142.811 134.025 116.035 1.00 62.06  ? 69  ILE   H N   1 
ATOM   3358 C CA  . ILE   C 3 73  ? 143.987 134.846 116.284 1.00 61.57  ? 69  ILE   H CA  1 
ATOM   3359 C C   . ILE   C 3 73  ? 144.093 135.123 117.777 1.00 65.58  ? 69  ILE   H C   1 
ATOM   3360 O O   . ILE   C 3 73  ? 143.091 135.345 118.465 1.00 68.30  ? 69  ILE   H O   1 
ATOM   3361 C CB  . ILE   C 3 73  ? 143.967 136.165 115.474 1.00 63.07  ? 69  ILE   H CB  1 
ATOM   3362 C CG1 . ILE   C 3 73  ? 145.332 136.855 115.538 1.00 63.51  ? 69  ILE   H CG1 1 
ATOM   3363 C CG2 . ILE   C 3 73  ? 142.873 137.095 115.956 1.00 61.03  ? 69  ILE   H CG2 1 
ATOM   3364 C CD1 . ILE   C 3 73  ? 145.488 137.991 114.550 1.00 52.80  ? 69  ILE   H CD1 1 
ATOM   3365 N N   . SER   C 3 74  ? 145.323 135.077 118.284 1.00 64.12  ? 70  SER   H N   1 
ATOM   3366 C CA  . SER   C 3 74  ? 145.587 135.341 119.689 1.00 65.46  ? 70  SER   H CA  1 
ATOM   3367 C C   . SER   C 3 74  ? 146.964 135.973 119.820 1.00 67.91  ? 70  SER   H C   1 
ATOM   3368 O O   . SER   C 3 74  ? 147.840 135.779 118.973 1.00 74.45  ? 70  SER   H O   1 
ATOM   3369 C CB  . SER   C 3 74  ? 145.498 134.062 120.530 1.00 68.76  ? 70  SER   H CB  1 
ATOM   3370 N N   . ALA   C 3 75  ? 147.149 136.731 120.899 1.00 63.43  ? 71  ALA   H N   1 
ATOM   3371 C CA  . ALA   C 3 75  ? 148.399 137.434 121.140 1.00 67.11  ? 71  ALA   H CA  1 
ATOM   3372 C C   . ALA   C 3 75  ? 148.805 137.274 122.597 1.00 73.10  ? 71  ALA   H C   1 
ATOM   3373 O O   . ALA   C 3 75  ? 147.964 137.058 123.473 1.00 65.72  ? 71  ALA   H O   1 
ATOM   3374 C CB  . ALA   C 3 75  ? 148.286 138.922 120.785 1.00 65.16  ? 71  ALA   H CB  1 
ATOM   3375 N N   . ASP   C 3 76  ? 150.107 137.384 122.845 1.00 79.03  ? 72  ASP   H N   1 
ATOM   3376 C CA  . ASP   C 3 76  ? 150.647 137.252 124.193 1.00 78.12  ? 72  ASP   H CA  1 
ATOM   3377 C C   . ASP   C 3 76  ? 151.686 138.333 124.476 1.00 76.03  ? 72  ASP   H C   1 
ATOM   3378 O O   . ASP   C 3 76  ? 152.733 138.386 123.832 1.00 73.40  ? 72  ASP   H O   1 
ATOM   3379 C CB  . ASP   C 3 76  ? 151.264 135.865 124.388 1.00 82.39  ? 72  ASP   H CB  1 
ATOM   3380 N N   . ASN   C 3 80  ? 155.413 139.207 122.674 1.00 78.69  ? 76  ASN   H N   1 
ATOM   3381 C CA  . ASN   C 3 80  ? 155.870 139.994 121.534 1.00 79.78  ? 76  ASN   H CA  1 
ATOM   3382 C C   . ASN   C 3 80  ? 155.568 139.287 120.217 1.00 77.99  ? 76  ASN   H C   1 
ATOM   3383 O O   . ASN   C 3 80  ? 156.336 139.387 119.260 1.00 66.75  ? 76  ASN   H O   1 
ATOM   3384 C CB  . ASN   C 3 80  ? 157.370 140.277 121.644 1.00 78.15  ? 76  ASN   H CB  1 
ATOM   3385 N N   . THR   C 3 81  ? 154.447 138.569 120.175 1.00 80.81  ? 77  THR   H N   1 
ATOM   3386 C CA  . THR   C 3 81  ? 154.031 137.834 118.989 1.00 77.86  ? 77  THR   H CA  1 
ATOM   3387 C C   . THR   C 3 81  ? 152.514 137.720 118.966 1.00 73.49  ? 77  THR   H C   1 
ATOM   3388 O O   . THR   C 3 81  ? 151.885 137.544 120.013 1.00 74.44  ? 77  THR   H O   1 
ATOM   3389 C CB  . THR   C 3 81  ? 154.661 136.437 118.949 1.00 78.27  ? 77  THR   H CB  1 
ATOM   3390 N N   . ALA   C 3 82  ? 151.935 137.826 117.773 1.00 64.69  ? 78  ALA   H N   1 
ATOM   3391 C CA  . ALA   C 3 82  ? 150.513 137.604 117.558 1.00 64.86  ? 78  ALA   H CA  1 
ATOM   3392 C C   . ALA   C 3 82  ? 150.338 136.335 116.738 1.00 64.16  ? 78  ALA   H C   1 
ATOM   3393 O O   . ALA   C 3 82  ? 150.911 136.210 115.651 1.00 61.87  ? 78  ALA   H O   1 
ATOM   3394 C CB  . ALA   C 3 82  ? 149.869 138.793 116.845 1.00 60.13  ? 78  ALA   H CB  1 
ATOM   3395 N N   . TYR   C 3 83  ? 149.543 135.403 117.253 1.00 70.16  ? 79  TYR   H N   1 
ATOM   3396 C CA  . TYR   C 3 83  ? 149.423 134.069 116.681 1.00 66.74  ? 79  TYR   H CA  1 
ATOM   3397 C C   . TYR   C 3 83  ? 148.108 133.959 115.928 1.00 62.43  ? 79  TYR   H C   1 
ATOM   3398 O O   . TYR   C 3 83  ? 147.037 134.166 116.507 1.00 63.40  ? 79  TYR   H O   1 
ATOM   3399 C CB  . TYR   C 3 83  ? 149.503 132.990 117.769 1.00 70.32  ? 79  TYR   H CB  1 
ATOM   3400 C CG  . TYR   C 3 83  ? 150.630 133.189 118.759 1.00 72.54  ? 79  TYR   H CG  1 
ATOM   3401 C CD1 . TYR   C 3 83  ? 150.507 134.083 119.816 1.00 74.59  ? 79  TYR   H CD1 1 
ATOM   3402 C CD2 . TYR   C 3 83  ? 151.824 132.493 118.629 1.00 74.24  ? 79  TYR   H CD2 1 
ATOM   3403 C CE1 . TYR   C 3 83  ? 151.535 134.272 120.717 1.00 79.37  ? 79  TYR   H CE1 1 
ATOM   3404 C CE2 . TYR   C 3 83  ? 152.859 132.675 119.526 1.00 83.06  ? 79  TYR   H CE2 1 
ATOM   3405 C CZ  . TYR   C 3 83  ? 152.709 133.565 120.568 1.00 87.52  ? 79  TYR   H CZ  1 
ATOM   3406 O OH  . TYR   C 3 83  ? 153.736 133.750 121.464 1.00 92.83  ? 79  TYR   H OH  1 
ATOM   3407 N N   . LEU   C 3 84  ? 148.193 133.631 114.642 1.00 57.97  ? 80  LEU   H N   1 
ATOM   3408 C CA  . LEU   C 3 84  ? 147.026 133.443 113.792 1.00 58.81  ? 80  LEU   H CA  1 
ATOM   3409 C C   . LEU   C 3 84  ? 146.890 131.965 113.464 1.00 58.46  ? 80  LEU   H C   1 
ATOM   3410 O O   . LEU   C 3 84  ? 147.769 131.386 112.817 1.00 54.83  ? 80  LEU   H O   1 
ATOM   3411 C CB  . LEU   C 3 84  ? 147.140 134.266 112.506 1.00 50.64  ? 80  LEU   H CB  1 
ATOM   3412 C CG  . LEU   C 3 84  ? 146.221 133.857 111.354 1.00 48.80  ? 80  LEU   H CG  1 
ATOM   3413 C CD1 . LEU   C 3 84  ? 144.790 134.289 111.632 1.00 57.04  ? 80  LEU   H CD1 1 
ATOM   3414 C CD2 . LEU   C 3 84  ? 146.714 134.432 110.038 1.00 39.87  ? 80  LEU   H CD2 1 
ATOM   3415 N N   . GLN   C 3 85  ? 145.794 131.360 113.910 1.00 61.18  ? 81  GLN   H N   1 
ATOM   3416 C CA  . GLN   C 3 85  ? 145.517 129.951 113.672 1.00 60.42  ? 81  GLN   H CA  1 
ATOM   3417 C C   . GLN   C 3 85  ? 144.381 129.830 112.668 1.00 58.41  ? 81  GLN   H C   1 
ATOM   3418 O O   . GLN   C 3 85  ? 143.337 130.473 112.822 1.00 56.99  ? 81  GLN   H O   1 
ATOM   3419 C CB  . GLN   C 3 85  ? 145.157 129.234 114.975 1.00 63.77  ? 81  GLN   H CB  1 
ATOM   3420 N N   . MET   C 3 86  ? 144.588 129.009 111.643 1.00 60.34  ? 82  MET   H N   1 
ATOM   3421 C CA  . MET   C 3 86  ? 143.613 128.808 110.583 1.00 63.05  ? 82  MET   H CA  1 
ATOM   3422 C C   . MET   C 3 86  ? 143.059 127.396 110.671 1.00 62.72  ? 82  MET   H C   1 
ATOM   3423 O O   . MET   C 3 86  ? 143.823 126.432 110.769 1.00 61.54  ? 82  MET   H O   1 
ATOM   3424 C CB  . MET   C 3 86  ? 144.238 129.045 109.208 1.00 56.76  ? 82  MET   H CB  1 
ATOM   3425 C CG  . MET   C 3 86  ? 143.951 130.419 108.638 1.00 52.68  ? 82  MET   H CG  1 
ATOM   3426 S SD  . MET   C 3 86  ? 145.015 130.842 107.251 1.00 48.44  ? 82  MET   H SD  1 
ATOM   3427 C CE  . MET   C 3 86  ? 146.563 131.106 108.101 1.00 42.70  ? 82  MET   H CE  1 
ATOM   3428 N N   . ASN   C 3 87  ? 141.735 127.278 110.640 1.00 64.00  ? 83  ASN   H N   1 
ATOM   3429 C CA  . ASN   C 3 87  ? 141.067 125.988 110.667 1.00 67.07  ? 83  ASN   H CA  1 
ATOM   3430 C C   . ASN   C 3 87  ? 140.182 125.858 109.436 1.00 68.50  ? 83  ASN   H C   1 
ATOM   3431 O O   . ASN   C 3 87  ? 139.617 126.838 108.946 1.00 66.40  ? 83  ASN   H O   1 
ATOM   3432 C CB  . ASN   C 3 87  ? 140.231 125.807 111.943 1.00 67.87  ? 83  ASN   H CB  1 
ATOM   3433 N N   . SER   C 3 88  ? 140.073 124.624 108.944 1.00 68.51  ? 84  SER   H N   1 
ATOM   3434 C CA  . SER   C 3 88  ? 139.294 124.310 107.748 1.00 64.37  ? 84  SER   H CA  1 
ATOM   3435 C C   . SER   C 3 88  ? 139.766 125.138 106.553 1.00 62.51  ? 84  SER   H C   1 
ATOM   3436 O O   . SER   C 3 88  ? 138.990 125.846 105.907 1.00 64.66  ? 84  SER   H O   1 
ATOM   3437 C CB  . SER   C 3 88  ? 137.797 124.508 107.999 1.00 69.56  ? 84  SER   H CB  1 
ATOM   3438 N N   . LEU   C 3 89  ? 141.063 125.046 106.269 1.00 61.08  ? 85  LEU   H N   1 
ATOM   3439 C CA  . LEU   C 3 89  ? 141.632 125.749 105.128 1.00 57.90  ? 85  LEU   H CA  1 
ATOM   3440 C C   . LEU   C 3 89  ? 140.979 125.281 103.833 1.00 55.18  ? 85  LEU   H C   1 
ATOM   3441 O O   . LEU   C 3 89  ? 140.712 124.093 103.638 1.00 65.17  ? 85  LEU   H O   1 
ATOM   3442 C CB  . LEU   C 3 89  ? 143.143 125.524 105.062 1.00 56.72  ? 85  LEU   H CB  1 
ATOM   3443 C CG  . LEU   C 3 89  ? 144.016 126.436 105.926 1.00 59.53  ? 85  LEU   H CG  1 
ATOM   3444 C CD1 . LEU   C 3 89  ? 145.488 126.129 105.711 1.00 54.31  ? 85  LEU   H CD1 1 
ATOM   3445 C CD2 . LEU   C 3 89  ? 143.723 127.894 105.631 1.00 59.08  ? 85  LEU   H CD2 1 
ATOM   3446 N N   . ARG   C 3 90  ? 140.719 126.233 102.942 1.00 43.93  ? 86  ARG   H N   1 
ATOM   3447 C CA  . ARG   C 3 90  ? 140.092 125.953 101.661 1.00 44.52  ? 86  ARG   H CA  1 
ATOM   3448 C C   . ARG   C 3 90  ? 141.108 126.158 100.545 1.00 44.07  ? 86  ARG   H C   1 
ATOM   3449 O O   . ARG   C 3 90  ? 142.258 126.538 100.781 1.00 43.81  ? 86  ARG   H O   1 
ATOM   3450 C CB  . ARG   C 3 90  ? 138.859 126.839 101.436 1.00 42.91  ? 86  ARG   H CB  1 
ATOM   3451 N N   . ALA   C 3 91  ? 140.670 125.883 99.314  1.00 46.81  ? 87  ALA   H N   1 
ATOM   3452 C CA  . ALA   C 3 91  ? 141.540 126.081 98.159  1.00 46.79  ? 87  ALA   H CA  1 
ATOM   3453 C C   . ALA   C 3 91  ? 141.837 127.559 97.938  1.00 44.42  ? 87  ALA   H C   1 
ATOM   3454 O O   . ALA   C 3 91  ? 142.964 127.928 97.589  1.00 44.80  ? 87  ALA   H O   1 
ATOM   3455 C CB  . ALA   C 3 91  ? 140.904 125.469 96.912  1.00 51.22  ? 87  ALA   H CB  1 
ATOM   3456 N N   . GLU   C 3 92  ? 140.835 128.420 98.133  1.00 44.91  ? 88  GLU   H N   1 
ATOM   3457 C CA  . GLU   C 3 92  ? 141.027 129.852 97.939  1.00 41.85  ? 88  GLU   H CA  1 
ATOM   3458 C C   . GLU   C 3 92  ? 141.905 130.472 99.016  1.00 35.08  ? 88  GLU   H C   1 
ATOM   3459 O O   . GLU   C 3 92  ? 142.375 131.601 98.843  1.00 34.47  ? 88  GLU   H O   1 
ATOM   3460 C CB  . GLU   C 3 92  ? 139.674 130.566 97.906  1.00 41.79  ? 88  GLU   H CB  1 
ATOM   3461 C CG  . GLU   C 3 92  ? 138.760 130.120 96.778  1.00 49.79  ? 88  GLU   H CG  1 
ATOM   3462 C CD  . GLU   C 3 92  ? 137.913 128.921 97.154  1.00 57.35  ? 88  GLU   H CD  1 
ATOM   3463 O OE1 . GLU   C 3 92  ? 137.961 128.505 98.331  1.00 56.10  ? 88  GLU   H OE1 1 
ATOM   3464 O OE2 . GLU   C 3 92  ? 137.203 128.392 96.274  1.00 61.35  ? 88  GLU   H OE2 1 
ATOM   3465 N N   . ASP   C 3 93  ? 142.138 129.763 100.123 1.00 35.86  ? 89  ASP   H N   1 
ATOM   3466 C CA  . ASP   C 3 93  ? 142.859 130.353 101.244 1.00 34.14  ? 89  ASP   H CA  1 
ATOM   3467 C C   . ASP   C 3 93  ? 144.349 130.505 100.973 1.00 32.56  ? 89  ASP   H C   1 
ATOM   3468 O O   . ASP   C 3 93  ? 145.050 131.119 101.785 1.00 30.10  ? 89  ASP   H O   1 
ATOM   3469 C CB  . ASP   C 3 93  ? 142.638 129.521 102.508 1.00 42.78  ? 89  ASP   H CB  1 
ATOM   3470 C CG  . ASP   C 3 93  ? 141.304 129.812 103.169 1.00 47.31  ? 89  ASP   H CG  1 
ATOM   3471 O OD1 . ASP   C 3 93  ? 140.481 130.524 102.557 1.00 42.45  ? 89  ASP   H OD1 1 
ATOM   3472 O OD2 . ASP   C 3 93  ? 141.080 129.336 104.301 1.00 52.26  ? 89  ASP   H OD2 1 
ATOM   3473 N N   . THR   C 3 94  ? 144.857 129.958 99.870  1.00 33.16  ? 90  THR   H N   1 
ATOM   3474 C CA  . THR   C 3 94  ? 146.252 130.186 99.522  1.00 32.38  ? 90  THR   H CA  1 
ATOM   3475 C C   . THR   C 3 94  ? 146.458 131.647 99.142  1.00 31.40  ? 90  THR   H C   1 
ATOM   3476 O O   . THR   C 3 94  ? 145.672 132.223 98.384  1.00 34.24  ? 90  THR   H O   1 
ATOM   3477 C CB  . THR   C 3 94  ? 146.688 129.261 98.382  1.00 29.90  ? 90  THR   H CB  1 
ATOM   3478 O OG1 . THR   C 3 94  ? 148.037 129.564 98.006  1.00 28.50  ? 90  THR   H OG1 1 
ATOM   3479 C CG2 . THR   C 3 94  ? 145.778 129.405 97.172  1.00 28.07  ? 90  THR   H CG2 1 
ATOM   3480 N N   . ALA   C 3 95  ? 147.511 132.251 99.690  1.00 29.29  ? 91  ALA   H N   1 
ATOM   3481 C CA  . ALA   C 3 95  ? 147.764 133.671 99.490  1.00 24.97  ? 91  ALA   H CA  1 
ATOM   3482 C C   . ALA   C 3 95  ? 149.146 134.051 99.997  1.00 27.09  ? 91  ALA   H C   1 
ATOM   3483 O O   . ALA   C 3 95  ? 149.942 133.181 100.366 1.00 32.79  ? 91  ALA   H O   1 
ATOM   3484 C CB  . ALA   C 3 95  ? 146.699 134.513 100.195 1.00 24.00  ? 91  ALA   H CB  1 
ATOM   3485 N N   . VAL   C 3 96  ? 149.442 135.346 100.006 1.00 24.11  ? 92  VAL   H N   1 
ATOM   3486 C CA  . VAL   C 3 96  ? 150.615 135.886 100.680 1.00 24.08  ? 92  VAL   H CA  1 
ATOM   3487 C C   . VAL   C 3 96  ? 150.124 136.691 101.871 1.00 25.73  ? 92  VAL   H C   1 
ATOM   3488 O O   . VAL   C 3 96  ? 149.268 137.572 101.723 1.00 24.18  ? 92  VAL   H O   1 
ATOM   3489 C CB  . VAL   C 3 96  ? 151.461 136.753 99.733  1.00 22.19  ? 92  VAL   H CB  1 
ATOM   3490 C CG1 . VAL   C 3 96  ? 152.633 137.362 100.482 1.00 23.50  ? 92  VAL   H CG1 1 
ATOM   3491 C CG2 . VAL   C 3 96  ? 151.945 135.934 98.552  1.00 26.03  ? 92  VAL   H CG2 1 
ATOM   3492 N N   . TYR   C 3 97  ? 150.651 136.385 103.052 1.00 28.39  ? 93  TYR   H N   1 
ATOM   3493 C CA  . TYR   C 3 97  ? 150.182 136.979 104.294 1.00 24.37  ? 93  TYR   H CA  1 
ATOM   3494 C C   . TYR   C 3 97  ? 151.187 138.000 104.805 1.00 25.56  ? 93  TYR   H C   1 
ATOM   3495 O O   . TYR   C 3 97  ? 152.381 137.707 104.924 1.00 26.80  ? 93  TYR   H O   1 
ATOM   3496 C CB  . TYR   C 3 97  ? 149.936 135.906 105.359 1.00 24.26  ? 93  TYR   H CB  1 
ATOM   3497 C CG  . TYR   C 3 97  ? 148.763 135.004 105.055 1.00 24.19  ? 93  TYR   H CG  1 
ATOM   3498 C CD1 . TYR   C 3 97  ? 148.900 133.920 104.201 1.00 24.20  ? 93  TYR   H CD1 1 
ATOM   3499 C CD2 . TYR   C 3 97  ? 147.513 135.244 105.613 1.00 24.63  ? 93  TYR   H CD2 1 
ATOM   3500 C CE1 . TYR   C 3 97  ? 147.830 133.097 103.917 1.00 27.19  ? 93  TYR   H CE1 1 
ATOM   3501 C CE2 . TYR   C 3 97  ? 146.436 134.426 105.333 1.00 24.43  ? 93  TYR   H CE2 1 
ATOM   3502 C CZ  . TYR   C 3 97  ? 146.602 133.353 104.483 1.00 25.99  ? 93  TYR   H CZ  1 
ATOM   3503 O OH  . TYR   C 3 97  ? 145.540 132.528 104.197 1.00 29.37  ? 93  TYR   H OH  1 
ATOM   3504 N N   . TYR   C 3 98  ? 150.690 139.196 105.108 1.00 24.26  ? 94  TYR   H N   1 
ATOM   3505 C CA  . TYR   C 3 98  ? 151.493 140.281 105.647 1.00 21.89  ? 94  TYR   H CA  1 
ATOM   3506 C C   . TYR   C 3 98  ? 150.987 140.597 107.043 1.00 22.55  ? 94  TYR   H C   1 
ATOM   3507 O O   . TYR   C 3 98  ? 149.795 140.456 107.326 1.00 20.76  ? 94  TYR   H O   1 
ATOM   3508 C CB  . TYR   C 3 98  ? 151.395 141.552 104.791 1.00 20.14  ? 94  TYR   H CB  1 
ATOM   3509 C CG  . TYR   C 3 98  ? 151.777 141.379 103.344 1.00 19.45  ? 94  TYR   H CG  1 
ATOM   3510 C CD1 . TYR   C 3 98  ? 153.104 141.269 102.960 1.00 23.39  ? 94  TYR   H CD1 1 
ATOM   3511 C CD2 . TYR   C 3 98  ? 150.802 141.339 102.356 1.00 18.05  ? 94  TYR   H CD2 1 
ATOM   3512 C CE1 . TYR   C 3 98  ? 153.448 141.113 101.633 1.00 25.98  ? 94  TYR   H CE1 1 
ATOM   3513 C CE2 . TYR   C 3 98  ? 151.135 141.184 101.031 1.00 18.36  ? 94  TYR   H CE2 1 
ATOM   3514 C CZ  . TYR   C 3 98  ? 152.459 141.072 100.674 1.00 22.72  ? 94  TYR   H CZ  1 
ATOM   3515 O OH  . TYR   C 3 98  ? 152.795 140.918 99.350  1.00 27.29  ? 94  TYR   H OH  1 
ATOM   3516 N N   . CYS   C 3 99  ? 151.889 141.027 107.919 1.00 24.21  ? 95  CYS   H N   1 
ATOM   3517 C CA  . CYS   C 3 99  ? 151.491 141.543 109.219 1.00 25.84  ? 95  CYS   H CA  1 
ATOM   3518 C C   . CYS   C 3 99  ? 151.976 142.977 109.358 1.00 21.93  ? 95  CYS   H C   1 
ATOM   3519 O O   . CYS   C 3 99  ? 153.154 143.267 109.123 1.00 24.32  ? 95  CYS   H O   1 
ATOM   3520 C CB  . CYS   C 3 99  ? 152.000 140.677 110.377 1.00 39.82  ? 95  CYS   H CB  1 
ATOM   3521 S SG  . CYS   C 3 99  ? 153.768 140.406 110.537 1.00 55.35  ? 95  CYS   H SG  1 
ATOM   3522 N N   . ALA   C 3 100 ? 151.062 143.865 109.739 1.00 20.81  ? 96  ALA   H N   1 
ATOM   3523 C CA  . ALA   C 3 100 ? 151.313 145.294 109.770 1.00 21.17  ? 96  ALA   H CA  1 
ATOM   3524 C C   . ALA   C 3 100 ? 150.899 145.864 111.119 1.00 22.97  ? 96  ALA   H C   1 
ATOM   3525 O O   . ALA   C 3 100 ? 149.969 145.378 111.767 1.00 28.21  ? 96  ALA   H O   1 
ATOM   3526 C CB  . ALA   C 3 100 ? 150.562 146.011 108.643 1.00 18.51  ? 96  ALA   H CB  1 
ATOM   3527 N N   . ARG   C 3 101 ? 151.598 146.921 111.521 1.00 20.27  ? 97  ARG   H N   1 
ATOM   3528 C CA  . ARG   C 3 101 ? 151.450 147.542 112.829 1.00 21.82  ? 97  ARG   H CA  1 
ATOM   3529 C C   . ARG   C 3 101 ? 150.322 148.560 112.793 1.00 20.73  ? 97  ARG   H C   1 
ATOM   3530 O O   . ARG   C 3 101 ? 150.023 149.126 111.739 1.00 26.37  ? 97  ARG   H O   1 
ATOM   3531 C CB  . ARG   C 3 101 ? 152.757 148.217 113.243 1.00 31.05  ? 97  ARG   H CB  1 
ATOM   3532 C CG  . ARG   C 3 101 ? 152.883 148.566 114.710 1.00 35.04  ? 97  ARG   H CG  1 
ATOM   3533 C CD  . ARG   C 3 101 ? 154.088 149.469 114.906 1.00 40.34  ? 97  ARG   H CD  1 
ATOM   3534 N NE  . ARG   C 3 101 ? 153.872 150.791 114.332 1.00 38.80  ? 97  ARG   H NE  1 
ATOM   3535 C CZ  . ARG   C 3 101 ? 154.189 151.929 114.933 1.00 39.49  ? 97  ARG   H CZ  1 
ATOM   3536 N NH1 . ARG   C 3 101 ? 154.800 151.945 116.105 1.00 41.29  ? 97  ARG   H NH1 1 
ATOM   3537 N NH2 . ARG   C 3 101 ? 153.894 153.081 114.338 1.00 36.77  ? 97  ARG   H NH2 1 
ATOM   3538 N N   . GLY   C 3 102 ? 149.697 148.793 113.945 1.00 19.96  ? 98  GLY   H N   1 
ATOM   3539 C CA  . GLY   C 3 102 ? 148.612 149.746 114.039 1.00 22.81  ? 98  GLY   H CA  1 
ATOM   3540 C C   . GLY   C 3 102 ? 148.442 150.226 115.464 1.00 33.00  ? 98  GLY   H C   1 
ATOM   3541 O O   . GLY   C 3 102 ? 149.191 149.841 116.362 1.00 41.16  ? 98  GLY   H O   1 
ATOM   3542 N N   . TYR   C 3 103 ? 147.446 151.085 115.665 1.00 34.42  ? 99  TYR   H N   1 
ATOM   3543 C CA  . TYR   C 3 103 ? 147.120 151.554 117.005 1.00 35.32  ? 99  TYR   H CA  1 
ATOM   3544 C C   . TYR   C 3 103 ? 146.380 150.478 117.791 1.00 36.09  ? 99  TYR   H C   1 
ATOM   3545 O O   . TYR   C 3 103 ? 145.767 149.571 117.223 1.00 40.32  ? 99  TYR   H O   1 
ATOM   3546 C CB  . TYR   C 3 103 ? 146.264 152.820 116.950 1.00 34.48  ? 99  TYR   H CB  1 
ATOM   3547 C CG  . TYR   C 3 103 ? 146.909 154.024 116.299 1.00 30.30  ? 99  TYR   H CG  1 
ATOM   3548 C CD1 . TYR   C 3 103 ? 148.250 154.022 115.937 1.00 28.50  ? 99  TYR   H CD1 1 
ATOM   3549 C CD2 . TYR   C 3 103 ? 146.173 155.178 116.073 1.00 27.72  ? 99  TYR   H CD2 1 
ATOM   3550 C CE1 . TYR   C 3 103 ? 148.831 155.129 115.351 1.00 26.83  ? 99  TYR   H CE1 1 
ATOM   3551 C CE2 . TYR   C 3 103 ? 146.744 156.285 115.492 1.00 20.57  ? 99  TYR   H CE2 1 
ATOM   3552 C CZ  . TYR   C 3 103 ? 148.070 156.259 115.132 1.00 20.64  ? 99  TYR   H CZ  1 
ATOM   3553 O OH  . TYR   C 3 103 ? 148.631 157.372 114.551 1.00 17.67  ? 99  TYR   H OH  1 
ATOM   3554 N N   . GLN   C 3 104 ? 146.438 150.592 119.120 1.00 31.73  ? 100 GLN   H N   1 
ATOM   3555 C CA  . GLN   C 3 104 ? 145.750 149.631 119.976 1.00 35.95  ? 100 GLN   H CA  1 
ATOM   3556 C C   . GLN   C 3 104 ? 144.239 149.737 119.819 1.00 42.79  ? 100 GLN   H C   1 
ATOM   3557 O O   . GLN   C 3 104 ? 143.584 148.797 119.356 1.00 46.78  ? 100 GLN   H O   1 
ATOM   3558 C CB  . GLN   C 3 104 ? 146.158 149.843 121.434 1.00 43.44  ? 100 GLN   H CB  1 
ATOM   3559 C CG  . GLN   C 3 104 ? 145.387 148.988 122.427 1.00 46.44  ? 100 GLN   H CG  1 
ATOM   3560 C CD  . GLN   C 3 104 ? 145.835 149.205 123.859 1.00 45.33  ? 100 GLN   H CD  1 
ATOM   3561 O OE1 . GLN   C 3 104 ? 146.208 148.262 124.554 1.00 51.17  ? 100 GLN   H OE1 1 
ATOM   3562 N NE2 . GLN   C 3 104 ? 145.816 150.455 124.302 1.00 39.96  ? 100 GLN   H NE2 1 
ATOM   3563 N N   . TYR   C 3 105 ? 143.666 150.874 120.197 1.00 42.09  ? 101 TYR   H N   1 
ATOM   3564 C CA  . TYR   C 3 105 ? 142.227 151.101 120.059 1.00 41.70  ? 101 TYR   H CA  1 
ATOM   3565 C C   . TYR   C 3 105 ? 141.900 151.767 118.729 1.00 40.07  ? 101 TYR   H C   1 
ATOM   3566 O O   . TYR   C 3 105 ? 141.225 152.795 118.697 1.00 41.63  ? 101 TYR   H O   1 
ATOM   3567 C CB  . TYR   C 3 105 ? 141.707 151.945 121.217 1.00 40.36  ? 101 TYR   H CB  1 
ATOM   3568 C CG  . TYR   C 3 105 ? 141.999 151.400 122.596 1.00 44.89  ? 101 TYR   H CG  1 
ATOM   3569 C CD1 . TYR   C 3 105 ? 141.538 150.149 122.984 1.00 49.60  ? 101 TYR   H CD1 1 
ATOM   3570 C CD2 . TYR   C 3 105 ? 142.716 152.149 123.518 1.00 47.43  ? 101 TYR   H CD2 1 
ATOM   3571 C CE1 . TYR   C 3 105 ? 141.798 149.655 124.248 1.00 52.14  ? 101 TYR   H CE1 1 
ATOM   3572 C CE2 . TYR   C 3 105 ? 142.978 151.665 124.784 1.00 50.98  ? 101 TYR   H CE2 1 
ATOM   3573 C CZ  . TYR   C 3 105 ? 142.519 150.416 125.143 1.00 53.36  ? 101 TYR   H CZ  1 
ATOM   3574 O OH  . TYR   C 3 105 ? 142.779 149.929 126.402 1.00 51.48  ? 101 TYR   H OH  1 
ATOM   3575 N N   . TRP   C 3 106 ? 142.360 151.198 117.611 1.00 34.04  ? 102 TRP   H N   1 
ATOM   3576 C CA  . TRP   C 3 106 ? 142.146 151.863 116.330 1.00 35.26  ? 102 TRP   H CA  1 
ATOM   3577 C C   . TRP   C 3 106 ? 140.668 151.880 115.962 1.00 36.61  ? 102 TRP   H C   1 
ATOM   3578 O O   . TRP   C 3 106 ? 140.227 152.725 115.175 1.00 34.65  ? 102 TRP   H O   1 
ATOM   3579 C CB  . TRP   C 3 106 ? 142.964 151.200 115.221 1.00 39.78  ? 102 TRP   H CB  1 
ATOM   3580 C CG  . TRP   C 3 106 ? 142.737 149.733 115.045 1.00 37.19  ? 102 TRP   H CG  1 
ATOM   3581 C CD1 . TRP   C 3 106 ? 143.429 148.716 115.629 1.00 34.56  ? 102 TRP   H CD1 1 
ATOM   3582 C CD2 . TRP   C 3 106 ? 141.745 149.120 114.215 1.00 34.61  ? 102 TRP   H CD2 1 
ATOM   3583 N NE1 . TRP   C 3 106 ? 142.932 147.505 115.213 1.00 34.60  ? 102 TRP   H NE1 1 
ATOM   3584 C CE2 . TRP   C 3 106 ? 141.895 147.727 114.345 1.00 31.57  ? 102 TRP   H CE2 1 
ATOM   3585 C CE3 . TRP   C 3 106 ? 140.743 149.614 113.375 1.00 32.87  ? 102 TRP   H CE3 1 
ATOM   3586 C CZ2 . TRP   C 3 106 ? 141.083 146.826 113.669 1.00 31.37  ? 102 TRP   H CZ2 1 
ATOM   3587 C CZ3 . TRP   C 3 106 ? 139.937 148.717 112.706 1.00 32.59  ? 102 TRP   H CZ3 1 
ATOM   3588 C CH2 . TRP   C 3 106 ? 140.111 147.338 112.857 1.00 34.45  ? 102 TRP   H CH2 1 
ATOM   3589 N N   . GLN   C 3 107 ? 139.888 150.949 116.517 1.00 38.91  ? 103 GLN   H N   1 
ATOM   3590 C CA  . GLN   C 3 107 ? 138.445 150.975 116.305 1.00 39.18  ? 103 GLN   H CA  1 
ATOM   3591 C C   . GLN   C 3 107 ? 137.819 152.214 116.933 1.00 40.01  ? 103 GLN   H C   1 
ATOM   3592 O O   . GLN   C 3 107 ? 136.916 152.824 116.349 1.00 41.10  ? 103 GLN   H O   1 
ATOM   3593 C CB  . GLN   C 3 107 ? 137.807 149.705 116.866 1.00 42.58  ? 103 GLN   H CB  1 
ATOM   3594 N N   . TYR   C 3 108 ? 138.282 152.598 118.126 1.00 38.05  ? 104 TYR   H N   1 
ATOM   3595 C CA  . TYR   C 3 108 ? 137.805 153.833 118.740 1.00 36.11  ? 104 TYR   H CA  1 
ATOM   3596 C C   . TYR   C 3 108 ? 138.415 155.044 118.044 1.00 37.52  ? 104 TYR   H C   1 
ATOM   3597 O O   . TYR   C 3 108 ? 137.712 156.019 117.753 1.00 37.96  ? 104 TYR   H O   1 
ATOM   3598 C CB  . TYR   C 3 108 ? 138.144 153.827 120.237 1.00 36.67  ? 104 TYR   H CB  1 
ATOM   3599 C CG  . TYR   C 3 108 ? 138.280 155.184 120.923 1.00 45.53  ? 104 TYR   H CG  1 
ATOM   3600 C CD1 . TYR   C 3 108 ? 137.376 156.219 120.684 1.00 47.15  ? 104 TYR   H CD1 1 
ATOM   3601 C CD2 . TYR   C 3 108 ? 139.243 155.385 121.901 1.00 47.19  ? 104 TYR   H CD2 1 
ATOM   3602 C CE1 . TYR   C 3 108 ? 137.492 157.440 121.329 1.00 50.04  ? 104 TYR   H CE1 1 
ATOM   3603 C CE2 . TYR   C 3 108 ? 139.365 156.602 122.548 1.00 46.24  ? 104 TYR   H CE2 1 
ATOM   3604 C CZ  . TYR   C 3 108 ? 138.485 157.622 122.266 1.00 48.29  ? 104 TYR   H CZ  1 
ATOM   3605 O OH  . TYR   C 3 108 ? 138.604 158.827 122.922 1.00 41.46  ? 104 TYR   H OH  1 
ATOM   3606 N N   . HIS   C 3 109 ? 139.717 154.986 117.746 1.00 38.56  ? 105 HIS   H N   1 
ATOM   3607 C CA  . HIS   C 3 109 ? 140.408 156.136 117.169 1.00 37.19  ? 105 HIS   H CA  1 
ATOM   3608 C C   . HIS   C 3 109 ? 139.818 156.528 115.819 1.00 31.69  ? 105 HIS   H C   1 
ATOM   3609 O O   . HIS   C 3 109 ? 139.612 157.717 115.550 1.00 26.29  ? 105 HIS   H O   1 
ATOM   3610 C CB  . HIS   C 3 109 ? 141.901 155.837 117.023 1.00 34.04  ? 105 HIS   H CB  1 
ATOM   3611 C CG  . HIS   C 3 109 ? 142.611 155.623 118.323 1.00 32.79  ? 105 HIS   H CG  1 
ATOM   3612 N ND1 . HIS   C 3 109 ? 143.690 154.775 118.449 1.00 33.25  ? 105 HIS   H ND1 1 
ATOM   3613 C CD2 . HIS   C 3 109 ? 142.404 156.152 119.552 1.00 34.48  ? 105 HIS   H CD2 1 
ATOM   3614 C CE1 . HIS   C 3 109 ? 144.115 154.788 119.699 1.00 32.68  ? 105 HIS   H CE1 1 
ATOM   3615 N NE2 . HIS   C 3 109 ? 143.351 155.615 120.389 1.00 36.02  ? 105 HIS   H NE2 1 
ATOM   3616 N N   . ALA   C 3 110 ? 139.543 155.547 114.961 1.00 30.82  ? 106 ALA   H N   1 
ATOM   3617 C CA  . ALA   C 3 110 ? 139.049 155.842 113.623 1.00 28.28  ? 106 ALA   H CA  1 
ATOM   3618 C C   . ALA   C 3 110 ? 137.683 156.513 113.689 1.00 27.07  ? 106 ALA   H C   1 
ATOM   3619 O O   . ALA   C 3 110 ? 136.799 156.083 114.435 1.00 29.67  ? 106 ALA   H O   1 
ATOM   3620 C CB  . ALA   C 3 110 ? 138.972 154.561 112.795 1.00 30.48  ? 106 ALA   H CB  1 
ATOM   3621 N N   . SER   C 3 111 ? 137.516 157.572 112.900 1.00 22.57  ? 107 SER   H N   1 
ATOM   3622 C CA  . SER   C 3 111 ? 136.264 158.312 112.833 1.00 22.67  ? 107 SER   H CA  1 
ATOM   3623 C C   . SER   C 3 111 ? 136.136 158.904 111.437 1.00 26.13  ? 107 SER   H C   1 
ATOM   3624 O O   . SER   C 3 111 ? 136.899 158.568 110.528 1.00 31.83  ? 107 SER   H O   1 
ATOM   3625 C CB  . SER   C 3 111 ? 136.202 159.397 113.913 1.00 29.79  ? 107 SER   H CB  1 
ATOM   3626 O OG  . SER   C 3 111 ? 135.128 160.291 113.676 1.00 30.49  ? 107 SER   H OG  1 
ATOM   3627 N N   . TRP   C 3 112 ? 135.157 159.796 111.268 1.00 26.12  ? 108 TRP   H N   1 
ATOM   3628 C CA  . TRP   C 3 112 ? 134.944 160.408 109.960 1.00 28.07  ? 108 TRP   H CA  1 
ATOM   3629 C C   . TRP   C 3 112 ? 136.114 161.294 109.557 1.00 26.16  ? 108 TRP   H C   1 
ATOM   3630 O O   . TRP   C 3 112 ? 136.288 161.589 108.370 1.00 26.15  ? 108 TRP   H O   1 
ATOM   3631 C CB  . TRP   C 3 112 ? 133.649 161.221 109.959 1.00 28.22  ? 108 TRP   H CB  1 
ATOM   3632 C CG  . TRP   C 3 112 ? 133.745 162.503 110.730 1.00 30.09  ? 108 TRP   H CG  1 
ATOM   3633 C CD1 . TRP   C 3 112 ? 133.621 162.660 112.078 1.00 28.86  ? 108 TRP   H CD1 1 
ATOM   3634 C CD2 . TRP   C 3 112 ? 133.986 163.810 110.193 1.00 29.31  ? 108 TRP   H CD2 1 
ATOM   3635 N NE1 . TRP   C 3 112 ? 133.772 163.984 112.416 1.00 27.42  ? 108 TRP   H NE1 1 
ATOM   3636 C CE2 . TRP   C 3 112 ? 133.996 164.710 111.276 1.00 27.81  ? 108 TRP   H CE2 1 
ATOM   3637 C CE3 . TRP   C 3 112 ? 134.193 164.306 108.902 1.00 27.79  ? 108 TRP   H CE3 1 
ATOM   3638 C CZ2 . TRP   C 3 112 ? 134.206 166.077 111.108 1.00 26.76  ? 108 TRP   H CZ2 1 
ATOM   3639 C CZ3 . TRP   C 3 112 ? 134.402 165.664 108.738 1.00 28.92  ? 108 TRP   H CZ3 1 
ATOM   3640 C CH2 . TRP   C 3 112 ? 134.407 166.533 109.835 1.00 27.47  ? 108 TRP   H CH2 1 
ATOM   3641 N N   . TYR   C 3 113 ? 136.920 161.730 110.524 1.00 26.04  ? 109 TYR   H N   1 
ATOM   3642 C CA  . TYR   C 3 113 ? 138.026 162.640 110.264 1.00 28.72  ? 109 TYR   H CA  1 
ATOM   3643 C C   . TYR   C 3 113 ? 139.396 162.031 110.540 1.00 28.79  ? 109 TYR   H C   1 
ATOM   3644 O O   . TYR   C 3 113 ? 140.407 162.686 110.267 1.00 32.37  ? 109 TYR   H O   1 
ATOM   3645 C CB  . TYR   C 3 113 ? 137.847 163.927 111.091 1.00 27.21  ? 109 TYR   H CB  1 
ATOM   3646 C CG  . TYR   C 3 113 ? 138.166 163.804 112.572 1.00 26.76  ? 109 TYR   H CG  1 
ATOM   3647 C CD1 . TYR   C 3 113 ? 139.478 163.814 113.035 1.00 26.68  ? 109 TYR   H CD1 1 
ATOM   3648 C CD2 . TYR   C 3 113 ? 137.148 163.674 113.508 1.00 29.41  ? 109 TYR   H CD2 1 
ATOM   3649 C CE1 . TYR   C 3 113 ? 139.764 163.698 114.378 1.00 28.95  ? 109 TYR   H CE1 1 
ATOM   3650 C CE2 . TYR   C 3 113 ? 137.426 163.559 114.855 1.00 34.17  ? 109 TYR   H CE2 1 
ATOM   3651 C CZ  . TYR   C 3 113 ? 138.736 163.571 115.284 1.00 34.98  ? 109 TYR   H CZ  1 
ATOM   3652 O OH  . TYR   C 3 113 ? 139.022 163.458 116.624 1.00 36.01  ? 109 TYR   H OH  1 
ATOM   3653 N N   . TRP   C 3 114 ? 139.463 160.814 111.074 1.00 19.86  ? 110 TRP   H N   1 
ATOM   3654 C CA  . TRP   C 3 114 ? 140.732 160.217 111.467 1.00 16.39  ? 110 TRP   H CA  1 
ATOM   3655 C C   . TRP   C 3 114 ? 140.846 158.812 110.894 1.00 20.25  ? 110 TRP   H C   1 
ATOM   3656 O O   . TRP   C 3 114 ? 139.838 158.117 110.740 1.00 27.23  ? 110 TRP   H O   1 
ATOM   3657 C CB  . TRP   C 3 114 ? 140.874 160.176 112.994 1.00 16.78  ? 110 TRP   H CB  1 
ATOM   3658 C CG  . TRP   C 3 114 ? 142.103 159.456 113.454 1.00 14.76  ? 110 TRP   H CG  1 
ATOM   3659 C CD1 . TRP   C 3 114 ? 142.167 158.209 113.998 1.00 15.96  ? 110 TRP   H CD1 1 
ATOM   3660 C CD2 . TRP   C 3 114 ? 143.448 159.942 113.405 1.00 11.61  ? 110 TRP   H CD2 1 
ATOM   3661 N NE1 . TRP   C 3 114 ? 143.469 157.887 114.292 1.00 15.04  ? 110 TRP   H NE1 1 
ATOM   3662 C CE2 . TRP   C 3 114 ? 144.275 158.935 113.936 1.00 10.61  ? 110 TRP   H CE2 1 
ATOM   3663 C CE3 . TRP   C 3 114 ? 144.033 161.130 112.963 1.00 12.41  ? 110 TRP   H CE3 1 
ATOM   3664 C CZ2 . TRP   C 3 114 ? 145.655 159.080 114.035 1.00 8.67   ? 110 TRP   H CZ2 1 
ATOM   3665 C CZ3 . TRP   C 3 114 ? 145.401 161.271 113.062 1.00 10.44  ? 110 TRP   H CZ3 1 
ATOM   3666 C CH2 . TRP   C 3 114 ? 146.198 160.252 113.595 1.00 8.91   ? 110 TRP   H CH2 1 
ATOM   3667 N N   . ASN   C 3 115 ? 142.075 158.405 110.575 1.00 16.74  ? 111 ASN   H N   1 
ATOM   3668 C CA  . ASN   C 3 115 ? 142.357 157.035 110.152 1.00 13.80  ? 111 ASN   H CA  1 
ATOM   3669 C C   . ASN   C 3 115 ? 143.834 156.780 110.418 1.00 8.69   ? 111 ASN   H C   1 
ATOM   3670 O O   . ASN   C 3 115 ? 144.690 157.384 109.765 1.00 8.58   ? 111 ASN   H O   1 
ATOM   3671 C CB  . ASN   C 3 115 ? 142.014 156.832 108.682 1.00 15.43  ? 111 ASN   H CB  1 
ATOM   3672 C CG  . ASN   C 3 115 ? 142.229 155.401 108.218 1.00 14.15  ? 111 ASN   H CG  1 
ATOM   3673 O OD1 . ASN   C 3 115 ? 142.596 154.525 109.002 1.00 12.13  ? 111 ASN   H OD1 1 
ATOM   3674 N ND2 . ASN   C 3 115 ? 141.997 155.158 106.934 1.00 14.66  ? 111 ASN   H ND2 1 
ATOM   3675 N N   . GLY   C 3 116 ? 144.128 155.897 111.372 1.00 7.46   ? 112 GLY   H N   1 
ATOM   3676 C CA  . GLY   C 3 116 ? 145.511 155.688 111.768 1.00 7.72   ? 112 GLY   H CA  1 
ATOM   3677 C C   . GLY   C 3 116 ? 146.362 155.078 110.672 1.00 6.25   ? 112 GLY   H C   1 
ATOM   3678 O O   . GLY   C 3 116 ? 147.483 155.527 110.425 1.00 6.01   ? 112 GLY   H O   1 
ATOM   3679 N N   . GLY   C 3 117 ? 145.849 154.050 110.005 1.00 9.50   ? 113 GLY   H N   1 
ATOM   3680 C CA  . GLY   C 3 117 ? 146.575 153.395 108.940 1.00 10.29  ? 113 GLY   H CA  1 
ATOM   3681 C C   . GLY   C 3 117 ? 147.664 152.471 109.454 1.00 9.48   ? 113 GLY   H C   1 
ATOM   3682 O O   . GLY   C 3 117 ? 148.337 152.730 110.452 1.00 9.87   ? 113 GLY   H O   1 
ATOM   3683 N N   . LEU   C 3 118 ? 147.845 151.367 108.737 1.00 8.85   ? 114 LEU   H N   1 
ATOM   3684 C CA  . LEU   C 3 118 ? 148.856 150.366 109.064 1.00 10.96  ? 114 LEU   H CA  1 
ATOM   3685 C C   . LEU   C 3 118 ? 150.200 150.922 108.614 1.00 13.11  ? 114 LEU   H C   1 
ATOM   3686 O O   . LEU   C 3 118 ? 150.585 150.776 107.452 1.00 15.74  ? 114 LEU   H O   1 
ATOM   3687 C CB  . LEU   C 3 118 ? 148.544 149.030 108.399 1.00 13.03  ? 114 LEU   H CB  1 
ATOM   3688 C CG  . LEU   C 3 118 ? 147.069 148.644 108.260 1.00 12.83  ? 114 LEU   H CG  1 
ATOM   3689 C CD1 . LEU   C 3 118 ? 146.932 147.341 107.488 1.00 14.39  ? 114 LEU   H CD1 1 
ATOM   3690 C CD2 . LEU   C 3 118 ? 146.389 148.541 109.616 1.00 12.86  ? 114 LEU   H CD2 1 
ATOM   3691 N N   . ASP   C 3 119 ? 150.912 151.560 109.545 1.00 13.84  ? 115 ASP   H N   1 
ATOM   3692 C CA  . ASP   C 3 119 ? 152.095 152.336 109.185 1.00 18.51  ? 115 ASP   H CA  1 
ATOM   3693 C C   . ASP   C 3 119 ? 153.231 151.454 108.675 1.00 22.05  ? 115 ASP   H C   1 
ATOM   3694 O O   . ASP   C 3 119 ? 153.778 151.705 107.595 1.00 21.17  ? 115 ASP   H O   1 
ATOM   3695 C CB  . ASP   C 3 119 ? 152.550 153.159 110.389 1.00 20.52  ? 115 ASP   H CB  1 
ATOM   3696 C CG  . ASP   C 3 119 ? 152.309 152.444 111.703 1.00 22.72  ? 115 ASP   H CG  1 
ATOM   3697 O OD1 . ASP   C 3 119 ? 152.555 151.223 111.768 1.00 26.67  ? 115 ASP   H OD1 1 
ATOM   3698 O OD2 . ASP   C 3 119 ? 151.862 153.099 112.667 1.00 24.46  ? 115 ASP   H OD2 1 
ATOM   3699 N N   . TYR   C 3 120 ? 153.593 150.416 109.424 1.00 24.70  ? 116 TYR   H N   1 
ATOM   3700 C CA  . TYR   C 3 120 ? 154.743 149.582 109.103 1.00 27.08  ? 116 TYR   H CA  1 
ATOM   3701 C C   . TYR   C 3 120 ? 154.284 148.204 108.650 1.00 26.73  ? 116 TYR   H C   1 
ATOM   3702 O O   . TYR   C 3 120 ? 153.263 147.695 109.119 1.00 27.47  ? 116 TYR   H O   1 
ATOM   3703 C CB  . TYR   C 3 120 ? 155.683 149.451 110.305 1.00 30.92  ? 116 TYR   H CB  1 
ATOM   3704 C CG  . TYR   C 3 120 ? 156.284 150.764 110.752 1.00 35.17  ? 116 TYR   H CG  1 
ATOM   3705 C CD1 . TYR   C 3 120 ? 157.459 151.240 110.184 1.00 37.03  ? 116 TYR   H CD1 1 
ATOM   3706 C CD2 . TYR   C 3 120 ? 155.678 151.529 111.738 1.00 33.66  ? 116 TYR   H CD2 1 
ATOM   3707 C CE1 . TYR   C 3 120 ? 158.012 152.440 110.587 1.00 39.39  ? 116 TYR   H CE1 1 
ATOM   3708 C CE2 . TYR   C 3 120 ? 156.224 152.730 112.147 1.00 34.20  ? 116 TYR   H CE2 1 
ATOM   3709 C CZ  . TYR   C 3 120 ? 157.391 153.181 111.569 1.00 36.79  ? 116 TYR   H CZ  1 
ATOM   3710 O OH  . TYR   C 3 120 ? 157.937 154.376 111.974 1.00 33.46  ? 116 TYR   H OH  1 
ATOM   3711 N N   . TRP   C 3 121 ? 155.046 147.606 107.735 1.00 27.10  ? 117 TRP   H N   1 
ATOM   3712 C CA  . TRP   C 3 121 ? 154.701 146.325 107.140 1.00 26.33  ? 117 TRP   H CA  1 
ATOM   3713 C C   . TRP   C 3 121 ? 155.899 145.389 107.193 1.00 34.89  ? 117 TRP   H C   1 
ATOM   3714 O O   . TRP   C 3 121 ? 157.038 145.811 107.407 1.00 41.21  ? 117 TRP   H O   1 
ATOM   3715 C CB  . TRP   C 3 121 ? 154.231 146.485 105.687 1.00 21.94  ? 117 TRP   H CB  1 
ATOM   3716 C CG  . TRP   C 3 121 ? 152.891 147.130 105.555 1.00 18.47  ? 117 TRP   H CG  1 
ATOM   3717 C CD1 . TRP   C 3 121 ? 152.579 148.430 105.815 1.00 18.14  ? 117 TRP   H CD1 1 
ATOM   3718 C CD2 . TRP   C 3 121 ? 151.680 146.507 105.120 1.00 13.95  ? 117 TRP   H CD2 1 
ATOM   3719 N NE1 . TRP   C 3 121 ? 151.248 148.655 105.574 1.00 14.17  ? 117 TRP   H NE1 1 
ATOM   3720 C CE2 . TRP   C 3 121 ? 150.673 147.489 105.145 1.00 11.54  ? 117 TRP   H CE2 1 
ATOM   3721 C CE3 . TRP   C 3 121 ? 151.349 145.213 104.713 1.00 13.31  ? 117 TRP   H CE3 1 
ATOM   3722 C CZ2 . TRP   C 3 121 ? 149.358 147.218 104.781 1.00 11.28  ? 117 TRP   H CZ2 1 
ATOM   3723 C CZ3 . TRP   C 3 121 ? 150.044 144.947 104.350 1.00 13.63  ? 117 TRP   H CZ3 1 
ATOM   3724 C CH2 . TRP   C 3 121 ? 149.064 145.944 104.387 1.00 12.60  ? 117 TRP   H CH2 1 
ATOM   3725 N N   . GLY   C 3 122 ? 155.622 144.102 106.995 1.00 35.86  ? 118 GLY   H N   1 
ATOM   3726 C CA  . GLY   C 3 122 ? 156.654 143.085 107.013 1.00 35.81  ? 118 GLY   H CA  1 
ATOM   3727 C C   . GLY   C 3 122 ? 157.143 142.709 105.631 1.00 35.84  ? 118 GLY   H C   1 
ATOM   3728 O O   . GLY   C 3 122 ? 157.280 143.572 104.760 1.00 40.02  ? 118 GLY   H O   1 
ATOM   3729 N N   . GLN   C 3 123 ? 157.411 141.420 105.417 1.00 41.82  ? 119 GLN   H N   1 
ATOM   3730 C CA  . GLN   C 3 123 ? 157.902 140.935 104.136 1.00 48.01  ? 119 GLN   H CA  1 
ATOM   3731 C C   . GLN   C 3 123 ? 156.950 139.985 103.424 1.00 48.87  ? 119 GLN   H C   1 
ATOM   3732 O O   . GLN   C 3 123 ? 157.057 139.840 102.202 1.00 53.81  ? 119 GLN   H O   1 
ATOM   3733 C CB  . GLN   C 3 123 ? 159.257 140.229 104.312 1.00 51.61  ? 119 GLN   H CB  1 
ATOM   3734 N N   . GLY   C 3 124 ? 156.037 139.344 104.136 1.00 42.97  ? 120 GLY   H N   1 
ATOM   3735 C CA  . GLY   C 3 124 ? 155.099 138.436 103.496 1.00 40.24  ? 120 GLY   H CA  1 
ATOM   3736 C C   . GLY   C 3 124 ? 155.556 136.993 103.552 1.00 39.80  ? 120 GLY   H C   1 
ATOM   3737 O O   . GLY   C 3 124 ? 156.697 136.653 103.242 1.00 45.22  ? 120 GLY   H O   1 
ATOM   3738 N N   . THR   C 3 125 ? 154.633 136.122 103.957 1.00 32.78  ? 121 THR   H N   1 
ATOM   3739 C CA  . THR   C 3 125 ? 154.890 134.693 104.060 1.00 36.66  ? 121 THR   H CA  1 
ATOM   3740 C C   . THR   C 3 125 ? 153.948 133.942 103.133 1.00 38.31  ? 121 THR   H C   1 
ATOM   3741 O O   . THR   C 3 125 ? 152.724 134.024 103.277 1.00 34.10  ? 121 THR   H O   1 
ATOM   3742 C CB  . THR   C 3 125 ? 154.715 134.192 105.499 1.00 48.15  ? 121 THR   H CB  1 
ATOM   3743 N N   . LEU   C 3 126 ? 154.524 133.204 102.189 1.00 38.84  ? 122 LEU   H N   1 
ATOM   3744 C CA  . LEU   C 3 126 ? 153.754 132.484 101.183 1.00 36.26  ? 122 LEU   H CA  1 
ATOM   3745 C C   . LEU   C 3 126 ? 153.104 131.257 101.808 1.00 38.61  ? 122 LEU   H C   1 
ATOM   3746 O O   . LEU   C 3 126 ? 153.797 130.374 102.324 1.00 44.69  ? 122 LEU   H O   1 
ATOM   3747 C CB  . LEU   C 3 126 ? 154.643 132.079 100.010 1.00 34.08  ? 122 LEU   H CB  1 
ATOM   3748 C CG  . LEU   C 3 126 ? 153.919 131.507 98.789  1.00 44.37  ? 122 LEU   H CG  1 
ATOM   3749 C CD1 . LEU   C 3 126 ? 152.772 132.405 98.359  1.00 43.73  ? 122 LEU   H CD1 1 
ATOM   3750 C CD2 . LEU   C 3 126 ? 154.894 131.300 97.642  1.00 54.51  ? 122 LEU   H CD2 1 
ATOM   3751 N N   . VAL   C 3 127 ? 151.777 131.204 101.757 1.00 35.81  ? 123 VAL   H N   1 
ATOM   3752 C CA  . VAL   C 3 127 ? 151.003 130.055 102.210 1.00 36.71  ? 123 VAL   H CA  1 
ATOM   3753 C C   . VAL   C 3 127 ? 150.351 129.434 100.983 1.00 39.61  ? 123 VAL   H C   1 
ATOM   3754 O O   . VAL   C 3 127 ? 149.514 130.066 100.326 1.00 39.52  ? 123 VAL   H O   1 
ATOM   3755 C CB  . VAL   C 3 127 ? 149.956 130.447 103.258 1.00 29.74  ? 123 VAL   H CB  1 
ATOM   3756 C CG1 . VAL   C 3 127 ? 148.971 129.312 103.470 1.00 28.58  ? 123 VAL   H CG1 1 
ATOM   3757 C CG2 . VAL   C 3 127 ? 150.634 130.815 104.563 1.00 39.22  ? 123 VAL   H CG2 1 
ATOM   3758 N N   . THR   C 3 128 ? 150.732 128.200 100.670 1.00 38.04  ? 124 THR   H N   1 
ATOM   3759 C CA  . THR   C 3 128 ? 150.198 127.474 99.524  1.00 34.95  ? 124 THR   H CA  1 
ATOM   3760 C C   . THR   C 3 128 ? 149.491 126.221 100.027 1.00 31.53  ? 124 THR   H C   1 
ATOM   3761 O O   . THR   C 3 128 ? 150.044 125.468 100.835 1.00 35.58  ? 124 THR   H O   1 
ATOM   3762 C CB  . THR   C 3 128 ? 151.306 127.132 98.527  1.00 37.41  ? 124 THR   H CB  1 
ATOM   3763 O OG1 . THR   C 3 128 ? 150.789 126.269 97.506  1.00 35.37  ? 124 THR   H OG1 1 
ATOM   3764 C CG2 . THR   C 3 128 ? 152.488 126.467 99.220  1.00 33.91  ? 124 THR   H CG2 1 
ATOM   3765 N N   . VAL   C 3 129 ? 148.263 126.012 99.565  1.00 33.64  ? 125 VAL   H N   1 
ATOM   3766 C CA  . VAL   C 3 129 ? 147.500 124.810 99.874  1.00 37.92  ? 125 VAL   H CA  1 
ATOM   3767 C C   . VAL   C 3 129 ? 147.362 124.022 98.574  1.00 41.95  ? 125 VAL   H C   1 
ATOM   3768 O O   . VAL   C 3 129 ? 146.770 124.489 97.597  1.00 45.49  ? 125 VAL   H O   1 
ATOM   3769 C CB  . VAL   C 3 129 ? 146.151 125.138 100.524 1.00 37.08  ? 125 VAL   H CB  1 
ATOM   3770 C CG1 . VAL   C 3 129 ? 146.377 125.840 101.849 1.00 36.69  ? 125 VAL   H CG1 1 
ATOM   3771 C CG2 . VAL   C 3 129 ? 145.296 126.025 99.630  1.00 34.68  ? 125 VAL   H CG2 1 
ATOM   3772 N N   . SER   C 3 130 ? 147.948 122.827 98.545  1.00 40.44  ? 126 SER   H N   1 
ATOM   3773 C CA  . SER   C 3 130 ? 147.954 122.004 97.344  1.00 41.52  ? 126 SER   H CA  1 
ATOM   3774 C C   . SER   C 3 130 ? 147.906 120.537 97.735  1.00 45.21  ? 126 SER   H C   1 
ATOM   3775 O O   . SER   C 3 130 ? 148.729 120.077 98.532  1.00 45.85  ? 126 SER   H O   1 
ATOM   3776 C CB  . SER   C 3 130 ? 149.195 122.281 96.488  1.00 43.49  ? 126 SER   H CB  1 
ATOM   3777 N N   . SER   C 3 131 ? 146.944 119.808 97.169  1.00 48.18  ? 127 SER   H N   1 
ATOM   3778 C CA  . SER   C 3 131 ? 146.819 118.370 97.404  1.00 52.39  ? 127 SER   H CA  1 
ATOM   3779 C C   . SER   C 3 131 ? 147.585 117.612 96.319  1.00 53.19  ? 127 SER   H C   1 
ATOM   3780 O O   . SER   C 3 131 ? 147.068 116.725 95.637  1.00 49.31  ? 127 SER   H O   1 
ATOM   3781 C CB  . SER   C 3 131 ? 145.351 117.964 97.448  1.00 53.24  ? 127 SER   H CB  1 
ATOM   3782 N N   . ALA   C 3 132 ? 148.853 117.987 96.171  1.00 53.55  ? 128 ALA   H N   1 
ATOM   3783 C CA  . ALA   C 3 132 ? 149.720 117.374 95.177  1.00 52.10  ? 128 ALA   H CA  1 
ATOM   3784 C C   . ALA   C 3 132 ? 151.169 117.556 95.601  1.00 53.91  ? 128 ALA   H C   1 
ATOM   3785 O O   . ALA   C 3 132 ? 151.492 118.399 96.441  1.00 50.14  ? 128 ALA   H O   1 
ATOM   3786 C CB  . ALA   C 3 132 ? 149.488 117.965 93.782  1.00 48.82  ? 128 ALA   H CB  1 
ATOM   3787 N N   . SER   C 3 133 ? 152.041 116.751 95.002  1.00 56.34  ? 129 SER   H N   1 
ATOM   3788 C CA  . SER   C 3 133 ? 153.464 116.773 95.296  1.00 58.63  ? 129 SER   H CA  1 
ATOM   3789 C C   . SER   C 3 133 ? 154.218 117.295 94.083  1.00 58.70  ? 129 SER   H C   1 
ATOM   3790 O O   . SER   C 3 133 ? 153.630 117.600 93.041  1.00 62.23  ? 129 SER   H O   1 
ATOM   3791 C CB  . SER   C 3 133 ? 153.977 115.380 95.687  1.00 61.28  ? 129 SER   H CB  1 
ATOM   3792 N N   . THR   C 3 134 ? 155.537 117.403 94.233  1.00 57.85  ? 130 THR   H N   1 
ATOM   3793 C CA  . THR   C 3 134 ? 156.386 117.874 93.147  1.00 61.54  ? 130 THR   H CA  1 
ATOM   3794 C C   . THR   C 3 134 ? 156.241 116.974 91.928  1.00 61.94  ? 130 THR   H C   1 
ATOM   3795 O O   . THR   C 3 134 ? 156.319 115.747 92.031  1.00 64.40  ? 130 THR   H O   1 
ATOM   3796 C CB  . THR   C 3 134 ? 157.847 117.913 93.603  1.00 62.08  ? 130 THR   H CB  1 
ATOM   3797 O OG1 . THR   C 3 134 ? 157.977 118.798 94.722  1.00 63.17  ? 130 THR   H OG1 1 
ATOM   3798 C CG2 . THR   C 3 134 ? 158.745 118.395 92.477  1.00 74.72  ? 130 THR   H CG2 1 
ATOM   3799 N N   . LYS   C 3 135 ? 156.027 117.593 90.769  1.00 62.94  ? 131 LYS   H N   1 
ATOM   3800 C CA  . LYS   C 3 135 ? 155.840 116.871 89.521  1.00 65.23  ? 131 LYS   H CA  1 
ATOM   3801 C C   . LYS   C 3 135 ? 156.962 117.221 88.555  1.00 71.54  ? 131 LYS   H C   1 
ATOM   3802 O O   . LYS   C 3 135 ? 157.430 118.361 88.507  1.00 78.10  ? 131 LYS   H O   1 
ATOM   3803 C CB  . LYS   C 3 135 ? 154.482 117.191 88.882  1.00 66.97  ? 131 LYS   H CB  1 
ATOM   3804 N N   . GLY   C 3 136 ? 157.392 116.222 87.790  1.00 72.16  ? 132 GLY   H N   1 
ATOM   3805 C CA  . GLY   C 3 136 ? 158.427 116.411 86.804  1.00 77.63  ? 132 GLY   H CA  1 
ATOM   3806 C C   . GLY   C 3 136 ? 157.974 117.308 85.673  1.00 79.68  ? 132 GLY   H C   1 
ATOM   3807 O O   . GLY   C 3 136 ? 156.965 117.048 85.009  1.00 81.54  ? 132 GLY   H O   1 
ATOM   3808 N N   . PRO   C 3 137 ? 158.708 118.395 85.440  1.00 86.14  ? 133 PRO   H N   1 
ATOM   3809 C CA  . PRO   C 3 137 ? 158.343 119.310 84.352  1.00 87.91  ? 133 PRO   H CA  1 
ATOM   3810 C C   . PRO   C 3 137 ? 158.400 118.620 82.998  1.00 89.59  ? 133 PRO   H C   1 
ATOM   3811 O O   . PRO   C 3 137 ? 159.263 117.777 82.743  1.00 90.65  ? 133 PRO   H O   1 
ATOM   3812 C CB  . PRO   C 3 137 ? 159.388 120.429 84.453  1.00 87.24  ? 133 PRO   H CB  1 
ATOM   3813 C CG  . PRO   C 3 137 ? 160.503 119.862 85.265  1.00 90.38  ? 133 PRO   H CG  1 
ATOM   3814 C CD  . PRO   C 3 137 ? 159.904 118.839 86.175  1.00 89.56  ? 133 PRO   H CD  1 
ATOM   3815 N N   . SER   C 3 138 ? 157.464 118.989 82.129  1.00 88.86  ? 134 SER   H N   1 
ATOM   3816 C CA  . SER   C 3 138 ? 157.396 118.473 80.769  1.00 89.84  ? 134 SER   H CA  1 
ATOM   3817 C C   . SER   C 3 138 ? 157.703 119.602 79.796  1.00 89.87  ? 134 SER   H C   1 
ATOM   3818 O O   . SER   C 3 138 ? 157.069 120.661 79.849  1.00 87.74  ? 134 SER   H O   1 
ATOM   3819 C CB  . SER   C 3 138 ? 156.017 117.877 80.476  1.00 87.34  ? 134 SER   H CB  1 
ATOM   3820 N N   . VAL   C 3 139 ? 158.672 119.377 78.913  1.00 91.13  ? 135 VAL   H N   1 
ATOM   3821 C CA  . VAL   C 3 139 ? 159.127 120.384 77.964  1.00 88.83  ? 135 VAL   H CA  1 
ATOM   3822 C C   . VAL   C 3 139 ? 158.812 119.905 76.553  1.00 88.27  ? 135 VAL   H C   1 
ATOM   3823 O O   . VAL   C 3 139 ? 158.963 118.717 76.239  1.00 88.63  ? 135 VAL   H O   1 
ATOM   3824 C CB  . VAL   C 3 139 ? 160.627 120.694 78.143  1.00 89.70  ? 135 VAL   H CB  1 
ATOM   3825 C CG1 . VAL   C 3 139 ? 160.965 120.810 79.621  1.00 92.12  ? 135 VAL   H CG1 1 
ATOM   3826 C CG2 . VAL   C 3 139 ? 161.503 119.635 77.488  1.00 88.51  ? 135 VAL   H CG2 1 
ATOM   3827 N N   . PHE   C 3 140 ? 158.315 120.817 75.723  1.00 87.80  ? 136 PHE   H N   1 
ATOM   3828 C CA  . PHE   C 3 140 ? 158.046 120.561 74.319  1.00 92.92  ? 136 PHE   H CA  1 
ATOM   3829 C C   . PHE   C 3 140 ? 158.670 121.659 73.471  1.00 97.24  ? 136 PHE   H C   1 
ATOM   3830 O O   . PHE   C 3 140 ? 158.559 122.843 73.803  1.00 99.31  ? 136 PHE   H O   1 
ATOM   3831 C CB  . PHE   C 3 140 ? 156.538 120.496 74.025  1.00 94.04  ? 136 PHE   H CB  1 
ATOM   3832 C CG  . PHE   C 3 140 ? 155.698 120.079 75.201  1.00 94.81  ? 136 PHE   H CG  1 
ATOM   3833 C CD1 . PHE   C 3 140 ? 155.857 118.831 75.780  1.00 96.42  ? 136 PHE   H CD1 1 
ATOM   3834 C CD2 . PHE   C 3 140 ? 154.744 120.935 75.722  1.00 95.82  ? 136 PHE   H CD2 1 
ATOM   3835 C CE1 . PHE   C 3 140 ? 155.084 118.448 76.859  1.00 94.68  ? 136 PHE   H CE1 1 
ATOM   3836 C CE2 . PHE   C 3 140 ? 153.967 120.556 76.801  1.00 94.45  ? 136 PHE   H CE2 1 
ATOM   3837 C CZ  . PHE   C 3 140 ? 154.138 119.312 77.369  1.00 90.71  ? 136 PHE   H CZ  1 
ATOM   3838 N N   . PRO   C 3 141 ? 159.329 121.295 72.371  1.00 100.33 ? 137 PRO   H N   1 
ATOM   3839 C CA  . PRO   C 3 141 ? 159.904 122.317 71.486  1.00 107.16 ? 137 PRO   H CA  1 
ATOM   3840 C C   . PRO   C 3 141 ? 158.836 122.902 70.573  1.00 109.57 ? 137 PRO   H C   1 
ATOM   3841 O O   . PRO   C 3 141 ? 158.103 122.172 69.901  1.00 111.25 ? 137 PRO   H O   1 
ATOM   3842 C CB  . PRO   C 3 141 ? 160.963 121.544 70.692  1.00 113.12 ? 137 PRO   H CB  1 
ATOM   3843 C CG  . PRO   C 3 141 ? 160.452 120.140 70.662  1.00 107.05 ? 137 PRO   H CG  1 
ATOM   3844 C CD  . PRO   C 3 141 ? 159.608 119.927 71.900  1.00 99.35  ? 137 PRO   H CD  1 
ATOM   3845 N N   . LEU   C 3 142 ? 158.748 124.231 70.556  1.00 108.72 ? 138 LEU   H N   1 
ATOM   3846 C CA  . LEU   C 3 142 ? 157.772 124.938 69.728  1.00 111.51 ? 138 LEU   H CA  1 
ATOM   3847 C C   . LEU   C 3 142 ? 158.394 125.146 68.354  1.00 116.85 ? 138 LEU   H C   1 
ATOM   3848 O O   . LEU   C 3 142 ? 159.168 126.078 68.131  1.00 118.21 ? 138 LEU   H O   1 
ATOM   3849 C CB  . LEU   C 3 142 ? 157.371 126.256 70.379  1.00 109.23 ? 138 LEU   H CB  1 
ATOM   3850 C CG  . LEU   C 3 142 ? 156.686 126.129 71.741  1.00 102.51 ? 138 LEU   H CG  1 
ATOM   3851 C CD1 . LEU   C 3 142 ? 156.277 127.493 72.272  1.00 94.21  ? 138 LEU   H CD1 1 
ATOM   3852 C CD2 . LEU   C 3 142 ? 155.484 125.203 71.650  1.00 106.12 ? 138 LEU   H CD2 1 
ATOM   3853 N N   . ALA   C 3 143 ? 158.056 124.259 67.425  1.00 120.69 ? 139 ALA   H N   1 
ATOM   3854 C CA  . ALA   C 3 143 ? 158.639 124.320 66.095  1.00 126.54 ? 139 ALA   H CA  1 
ATOM   3855 C C   . ALA   C 3 143 ? 158.181 125.587 65.375  1.00 128.45 ? 139 ALA   H C   1 
ATOM   3856 O O   . ALA   C 3 143 ? 156.992 125.926 65.405  1.00 124.85 ? 139 ALA   H O   1 
ATOM   3857 C CB  . ALA   C 3 143 ? 158.252 123.085 65.281  1.00 127.52 ? 139 ALA   H CB  1 
ATOM   3858 N N   . PRO   C 3 144 ? 159.093 126.313 64.725  1.00 133.07 ? 140 PRO   H N   1 
ATOM   3859 C CA  . PRO   C 3 144 ? 158.685 127.505 63.971  1.00 134.63 ? 140 PRO   H CA  1 
ATOM   3860 C C   . PRO   C 3 144 ? 157.939 127.149 62.695  1.00 136.71 ? 140 PRO   H C   1 
ATOM   3861 O O   . PRO   C 3 144 ? 158.493 126.499 61.802  1.00 134.85 ? 140 PRO   H O   1 
ATOM   3862 C CB  . PRO   C 3 144 ? 160.018 128.203 63.671  1.00 133.30 ? 140 PRO   H CB  1 
ATOM   3863 C CG  . PRO   C 3 144 ? 161.029 127.106 63.692  1.00 135.03 ? 140 PRO   H CG  1 
ATOM   3864 C CD  . PRO   C 3 144 ? 160.553 126.114 64.715  1.00 134.99 ? 140 PRO   H CD  1 
ATOM   3865 N N   . SER   C 3 145 ? 156.680 127.564 62.604  1.00 138.47 ? 141 SER   H N   1 
ATOM   3866 C CA  . SER   C 3 145 ? 155.859 127.275 61.434  1.00 137.93 ? 141 SER   H CA  1 
ATOM   3867 C C   . SER   C 3 145 ? 156.379 128.003 60.198  1.00 134.85 ? 141 SER   H C   1 
ATOM   3868 O O   . SER   C 3 145 ? 156.920 127.384 59.282  1.00 125.69 ? 141 SER   H O   1 
ATOM   3869 C CB  . SER   C 3 145 ? 154.401 127.659 61.695  1.00 130.55 ? 141 SER   H CB  1 
ATOM   3870 N N   . THR   C 3 153 ? 161.566 137.159 60.546  1.00 127.79 ? 142 THR   H N   1 
ATOM   3871 C CA  . THR   C 3 153 ? 161.688 136.720 61.931  1.00 127.75 ? 142 THR   H CA  1 
ATOM   3872 C C   . THR   C 3 153 ? 160.641 135.662 62.266  1.00 127.57 ? 142 THR   H C   1 
ATOM   3873 O O   . THR   C 3 153 ? 159.441 135.937 62.252  1.00 122.63 ? 142 THR   H O   1 
ATOM   3874 C CB  . THR   C 3 153 ? 161.545 137.899 62.912  1.00 119.69 ? 142 THR   H CB  1 
ATOM   3875 N N   . ALA   C 3 154 ? 161.105 134.453 62.568  1.00 130.61 ? 143 ALA   H N   1 
ATOM   3876 C CA  . ALA   C 3 154 ? 160.240 133.331 62.912  1.00 127.97 ? 143 ALA   H CA  1 
ATOM   3877 C C   . ALA   C 3 154 ? 160.338 133.077 64.410  1.00 124.33 ? 143 ALA   H C   1 
ATOM   3878 O O   . ALA   C 3 154 ? 161.442 132.935 64.948  1.00 124.01 ? 143 ALA   H O   1 
ATOM   3879 C CB  . ALA   C 3 154 ? 160.625 132.079 62.125  1.00 127.45 ? 143 ALA   H CB  1 
ATOM   3880 N N   . ALA   C 3 155 ? 159.189 133.021 65.077  1.00 120.12 ? 144 ALA   H N   1 
ATOM   3881 C CA  . ALA   C 3 155 ? 159.157 132.846 66.520  1.00 120.45 ? 144 ALA   H CA  1 
ATOM   3882 C C   . ALA   C 3 155 ? 159.252 131.372 66.897  1.00 122.17 ? 144 ALA   H C   1 
ATOM   3883 O O   . ALA   C 3 155 ? 158.596 130.510 66.307  1.00 125.12 ? 144 ALA   H O   1 
ATOM   3884 C CB  . ALA   C 3 155 ? 157.879 133.450 67.104  1.00 111.06 ? 144 ALA   H CB  1 
ATOM   3885 N N   . LEU   C 3 156 ? 160.084 131.092 67.899  1.00 119.55 ? 145 LEU   H N   1 
ATOM   3886 C CA  . LEU   C 3 156 ? 160.237 129.745 68.428  1.00 116.14 ? 145 LEU   H CA  1 
ATOM   3887 C C   . LEU   C 3 156 ? 160.536 129.840 69.916  1.00 112.47 ? 145 LEU   H C   1 
ATOM   3888 O O   . LEU   C 3 156 ? 161.014 130.866 70.408  1.00 111.65 ? 145 LEU   H O   1 
ATOM   3889 C CB  . LEU   C 3 156 ? 161.337 128.968 67.689  1.00 119.16 ? 145 LEU   H CB  1 
ATOM   3890 C CG  . LEU   C 3 156 ? 162.782 129.474 67.771  1.00 118.88 ? 145 LEU   H CG  1 
ATOM   3891 C CD1 . LEU   C 3 156 ? 163.554 128.793 68.895  1.00 118.23 ? 145 LEU   H CD1 1 
ATOM   3892 C CD2 . LEU   C 3 156 ? 163.492 129.282 66.438  1.00 120.52 ? 145 LEU   H CD2 1 
ATOM   3893 N N   . GLY   C 3 157 ? 160.251 128.757 70.633  1.00 111.89 ? 146 GLY   H N   1 
ATOM   3894 C CA  . GLY   C 3 157 ? 160.455 128.758 72.067  1.00 103.85 ? 146 GLY   H CA  1 
ATOM   3895 C C   . GLY   C 3 157 ? 160.225 127.385 72.656  1.00 103.96 ? 146 GLY   H C   1 
ATOM   3896 O O   . GLY   C 3 157 ? 160.145 126.381 71.945  1.00 110.23 ? 146 GLY   H O   1 
ATOM   3897 N N   . CYS   C 3 158 ? 160.131 127.354 73.983  1.00 100.18 ? 147 CYS   H N   1 
ATOM   3898 C CA  . CYS   C 3 158 ? 159.910 126.126 74.730  1.00 101.72 ? 147 CYS   H CA  1 
ATOM   3899 C C   . CYS   C 3 158 ? 158.766 126.319 75.717  1.00 91.49  ? 147 CYS   H C   1 
ATOM   3900 O O   . CYS   C 3 158 ? 158.608 127.389 76.311  1.00 93.34  ? 147 CYS   H O   1 
ATOM   3901 C CB  . CYS   C 3 158 ? 161.182 125.695 75.474  1.00 102.98 ? 147 CYS   H CB  1 
ATOM   3902 S SG  . CYS   C 3 158 ? 162.448 124.967 74.405  1.00 115.33 ? 147 CYS   H SG  1 
ATOM   3903 N N   . LEU   C 3 159 ? 157.967 125.270 75.885  1.00 85.36  ? 148 LEU   H N   1 
ATOM   3904 C CA  . LEU   C 3 159 ? 156.808 125.287 76.766  1.00 79.13  ? 148 LEU   H CA  1 
ATOM   3905 C C   . LEU   C 3 159 ? 157.031 124.335 77.934  1.00 81.75  ? 148 LEU   H C   1 
ATOM   3906 O O   . LEU   C 3 159 ? 157.524 123.218 77.751  1.00 90.02  ? 148 LEU   H O   1 
ATOM   3907 C CB  . LEU   C 3 159 ? 155.537 124.900 76.003  1.00 82.23  ? 148 LEU   H CB  1 
ATOM   3908 C CG  . LEU   C 3 159 ? 154.264 124.635 76.811  1.00 72.24  ? 148 LEU   H CG  1 
ATOM   3909 C CD1 . LEU   C 3 159 ? 153.871 125.858 77.613  1.00 79.61  ? 148 LEU   H CD1 1 
ATOM   3910 C CD2 . LEU   C 3 159 ? 153.127 124.213 75.896  1.00 64.22  ? 148 LEU   H CD2 1 
ATOM   3911 N N   . VAL   C 3 160 ? 156.669 124.784 79.133  1.00 76.42  ? 149 VAL   H N   1 
ATOM   3912 C CA  . VAL   C 3 160 ? 156.793 123.991 80.352  1.00 79.16  ? 149 VAL   H CA  1 
ATOM   3913 C C   . VAL   C 3 160 ? 155.394 123.783 80.915  1.00 81.57  ? 149 VAL   H C   1 
ATOM   3914 O O   . VAL   C 3 160 ? 154.639 124.748 81.087  1.00 80.13  ? 149 VAL   H O   1 
ATOM   3915 C CB  . VAL   C 3 160 ? 157.709 124.666 81.384  1.00 79.31  ? 149 VAL   H CB  1 
ATOM   3916 C CG1 . VAL   C 3 160 ? 158.253 123.636 82.361  1.00 82.69  ? 149 VAL   H CG1 1 
ATOM   3917 C CG2 . VAL   C 3 160 ? 158.845 125.395 80.686  1.00 82.57  ? 149 VAL   H CG2 1 
ATOM   3918 N N   . LYS   C 3 161 ? 155.051 122.529 81.203  1.00 84.11  ? 150 LYS   H N   1 
ATOM   3919 C CA  . LYS   C 3 161 ? 153.703 122.167 81.612  1.00 77.10  ? 150 LYS   H CA  1 
ATOM   3920 C C   . LYS   C 3 161 ? 153.765 121.056 82.652  1.00 78.77  ? 150 LYS   H C   1 
ATOM   3921 O O   . LYS   C 3 161 ? 154.690 120.240 82.655  1.00 82.67  ? 150 LYS   H O   1 
ATOM   3922 C CB  . LYS   C 3 161 ? 152.870 121.729 80.393  1.00 76.09  ? 150 LYS   H CB  1 
ATOM   3923 C CG  . LYS   C 3 161 ? 151.484 121.182 80.698  1.00 76.57  ? 150 LYS   H CG  1 
ATOM   3924 C CD  . LYS   C 3 161 ? 150.600 122.224 81.356  1.00 70.96  ? 150 LYS   H CD  1 
ATOM   3925 C CE  . LYS   C 3 161 ? 149.325 121.594 81.887  1.00 69.56  ? 150 LYS   H CE  1 
ATOM   3926 N NZ  . LYS   C 3 161 ? 148.826 120.523 80.983  1.00 72.72  ? 150 LYS   H NZ  1 
ATOM   3927 N N   . ASP   C 3 162 ? 152.771 121.046 83.545  1.00 78.34  ? 151 ASP   H N   1 
ATOM   3928 C CA  . ASP   C 3 162 ? 152.555 119.976 84.519  1.00 78.20  ? 151 ASP   H CA  1 
ATOM   3929 C C   . ASP   C 3 162 ? 153.708 119.832 85.505  1.00 77.27  ? 151 ASP   H C   1 
ATOM   3930 O O   . ASP   C 3 162 ? 154.179 118.718 85.754  1.00 78.40  ? 151 ASP   H O   1 
ATOM   3931 C CB  . ASP   C 3 162 ? 152.293 118.635 83.822  1.00 78.26  ? 151 ASP   H CB  1 
ATOM   3932 N N   . TYR   C 3 163 ? 154.177 120.937 86.075  1.00 75.55  ? 152 TYR   H N   1 
ATOM   3933 C CA  . TYR   C 3 163 ? 155.286 120.887 87.018  1.00 79.29  ? 152 TYR   H CA  1 
ATOM   3934 C C   . TYR   C 3 163 ? 154.793 121.102 88.446  1.00 72.23  ? 152 TYR   H C   1 
ATOM   3935 O O   . TYR   C 3 163 ? 153.603 121.319 88.674  1.00 66.51  ? 152 TYR   H O   1 
ATOM   3936 C CB  . TYR   C 3 163 ? 156.358 121.920 86.628  1.00 78.39  ? 152 TYR   H CB  1 
ATOM   3937 C CG  . TYR   C 3 163 ? 156.019 123.375 86.901  1.00 77.97  ? 152 TYR   H CG  1 
ATOM   3938 C CD1 . TYR   C 3 163 ? 156.047 123.895 88.190  1.00 82.78  ? 152 TYR   H CD1 1 
ATOM   3939 C CD2 . TYR   C 3 163 ? 155.754 124.249 85.854  1.00 77.87  ? 152 TYR   H CD2 1 
ATOM   3940 C CE1 . TYR   C 3 163 ? 155.757 125.222 88.432  1.00 78.96  ? 152 TYR   H CE1 1 
ATOM   3941 C CE2 . TYR   C 3 163 ? 155.465 125.579 86.088  1.00 72.02  ? 152 TYR   H CE2 1 
ATOM   3942 C CZ  . TYR   C 3 163 ? 155.471 126.059 87.379  1.00 67.51  ? 152 TYR   H CZ  1 
ATOM   3943 O OH  . TYR   C 3 163 ? 155.191 127.383 87.619  1.00 68.58  ? 152 TYR   H OH  1 
ATOM   3944 N N   . VAL   C 3 168 ? 160.190 127.010 88.335  1.00 89.30  ? 153 VAL   H N   1 
ATOM   3945 C CA  . VAL   C 3 168 ? 160.829 126.579 87.099  1.00 94.45  ? 153 VAL   H CA  1 
ATOM   3946 C C   . VAL   C 3 168 ? 161.787 127.647 86.588  1.00 98.53  ? 153 VAL   H C   1 
ATOM   3947 O O   . VAL   C 3 168 ? 161.398 128.795 86.375  1.00 98.01  ? 153 VAL   H O   1 
ATOM   3948 C CB  . VAL   C 3 168 ? 159.784 126.231 86.024  1.00 90.67  ? 153 VAL   H CB  1 
ATOM   3949 C CG1 . VAL   C 3 168 ? 160.439 126.137 84.656  1.00 95.56  ? 153 VAL   H CG1 1 
ATOM   3950 C CG2 . VAL   C 3 168 ? 159.097 124.923 86.369  1.00 92.08  ? 153 VAL   H CG2 1 
ATOM   3951 N N   . THR   C 3 169 ? 163.045 127.257 86.393  1.00 103.00 ? 154 THR   H N   1 
ATOM   3952 C CA  . THR   C 3 169 ? 164.069 128.144 85.861  1.00 104.93 ? 154 THR   H CA  1 
ATOM   3953 C C   . THR   C 3 169 ? 164.340 127.762 84.415  1.00 107.64 ? 154 THR   H C   1 
ATOM   3954 O O   . THR   C 3 169 ? 164.759 126.635 84.135  1.00 108.98 ? 154 THR   H O   1 
ATOM   3955 C CB  . THR   C 3 169 ? 165.362 128.063 86.681  1.00 104.82 ? 154 THR   H CB  1 
ATOM   3956 N N   . VAL   C 3 170 ? 164.103 128.701 83.502  1.00 106.57 ? 155 VAL   H N   1 
ATOM   3957 C CA  . VAL   C 3 170 ? 164.262 128.473 82.072  1.00 108.33 ? 155 VAL   H CA  1 
ATOM   3958 C C   . VAL   C 3 170 ? 165.342 129.410 81.551  1.00 108.33 ? 155 VAL   H C   1 
ATOM   3959 O O   . VAL   C 3 170 ? 165.300 130.618 81.806  1.00 104.01 ? 155 VAL   H O   1 
ATOM   3960 C CB  . VAL   C 3 170 ? 162.939 128.677 81.307  1.00 104.10 ? 155 VAL   H CB  1 
ATOM   3961 C CG1 . VAL   C 3 170 ? 162.231 129.940 81.781  1.00 97.91  ? 155 VAL   H CG1 1 
ATOM   3962 C CG2 . VAL   C 3 170 ? 163.189 128.727 79.807  1.00 105.48 ? 155 VAL   H CG2 1 
ATOM   3963 N N   . SER   C 3 171 ? 166.315 128.850 80.835  1.00 114.17 ? 156 SER   H N   1 
ATOM   3964 C CA  . SER   C 3 171 ? 167.420 129.615 80.281  1.00 117.48 ? 156 SER   H CA  1 
ATOM   3965 C C   . SER   C 3 171 ? 167.622 129.239 78.821  1.00 119.58 ? 156 SER   H C   1 
ATOM   3966 O O   . SER   C 3 171 ? 167.330 128.114 78.406  1.00 118.63 ? 156 SER   H O   1 
ATOM   3967 C CB  . SER   C 3 171 ? 168.718 129.379 81.066  1.00 119.84 ? 156 SER   H CB  1 
ATOM   3968 N N   . TRP   C 3 172 ? 168.126 130.195 78.047  1.00 121.45 ? 157 TRP   H N   1 
ATOM   3969 C CA  . TRP   C 3 172 ? 168.376 129.980 76.628  1.00 126.66 ? 157 TRP   H CA  1 
ATOM   3970 C C   . TRP   C 3 172 ? 169.868 129.818 76.355  1.00 128.08 ? 157 TRP   H C   1 
ATOM   3971 O O   . TRP   C 3 172 ? 170.321 129.973 75.221  1.00 128.84 ? 157 TRP   H O   1 
ATOM   3972 C CB  . TRP   C 3 172 ? 167.812 131.137 75.802  1.00 123.58 ? 157 TRP   H CB  1 
ATOM   3973 N N   . VAL   C 3 181 ? 163.830 137.115 73.847  1.00 108.70 ? 163 VAL   H N   1 
ATOM   3974 C CA  . VAL   C 3 181 ? 163.518 136.053 74.794  1.00 109.83 ? 163 VAL   H CA  1 
ATOM   3975 C C   . VAL   C 3 181 ? 162.488 136.539 75.807  1.00 105.79 ? 163 VAL   H C   1 
ATOM   3976 O O   . VAL   C 3 181 ? 162.782 137.393 76.642  1.00 104.01 ? 163 VAL   H O   1 
ATOM   3977 C CB  . VAL   C 3 181 ? 164.786 135.552 75.506  1.00 114.35 ? 163 VAL   H CB  1 
ATOM   3978 C CG1 . VAL   C 3 181 ? 164.446 134.417 76.460  1.00 105.83 ? 163 VAL   H CG1 1 
ATOM   3979 C CG2 . VAL   C 3 181 ? 165.825 135.111 74.487  1.00 115.62 ? 163 VAL   H CG2 1 
ATOM   3980 N N   . HIS   C 3 182 ? 161.279 135.989 75.728  1.00 100.99 ? 164 HIS   H N   1 
ATOM   3981 C CA  . HIS   C 3 182 ? 160.181 136.359 76.610  1.00 97.02  ? 164 HIS   H CA  1 
ATOM   3982 C C   . HIS   C 3 182 ? 159.769 135.155 77.444  1.00 90.97  ? 164 HIS   H C   1 
ATOM   3983 O O   . HIS   C 3 182 ? 159.583 134.058 76.908  1.00 89.07  ? 164 HIS   H O   1 
ATOM   3984 C CB  . HIS   C 3 182 ? 158.984 136.884 75.811  1.00 93.51  ? 164 HIS   H CB  1 
ATOM   3985 C CG  . HIS   C 3 182 ? 159.253 138.170 75.094  1.00 94.98  ? 164 HIS   H CG  1 
ATOM   3986 N ND1 . HIS   C 3 182 ? 159.549 138.225 73.749  1.00 94.15  ? 164 HIS   H ND1 1 
ATOM   3987 C CD2 . HIS   C 3 182 ? 159.269 139.450 75.535  1.00 94.77  ? 164 HIS   H CD2 1 
ATOM   3988 C CE1 . HIS   C 3 182 ? 159.737 139.483 73.392  1.00 93.10  ? 164 HIS   H CE1 1 
ATOM   3989 N NE2 . HIS   C 3 182 ? 159.573 140.246 74.458  1.00 94.34  ? 164 HIS   H NE2 1 
ATOM   3990 N N   . THR   C 3 183 ? 159.632 135.363 78.750  1.00 89.33  ? 165 THR   H N   1 
ATOM   3991 C CA  . THR   C 3 183 ? 159.179 134.336 79.678  1.00 83.70  ? 165 THR   H CA  1 
ATOM   3992 C C   . THR   C 3 183 ? 157.913 134.819 80.372  1.00 79.23  ? 165 THR   H C   1 
ATOM   3993 O O   . THR   C 3 183 ? 157.893 135.914 80.944  1.00 79.23  ? 165 THR   H O   1 
ATOM   3994 C CB  . THR   C 3 183 ? 160.263 134.008 80.708  1.00 84.33  ? 165 THR   H CB  1 
ATOM   3995 O OG1 . THR   C 3 183 ? 161.286 133.218 80.089  1.00 93.58  ? 165 THR   H OG1 1 
ATOM   3996 C CG2 . THR   C 3 183 ? 159.674 133.236 81.879  1.00 85.72  ? 165 THR   H CG2 1 
ATOM   3997 N N   . PHE   C 3 184 ? 156.862 134.004 80.323  1.00 75.33  ? 166 PHE   H N   1 
ATOM   3998 C CA  . PHE   C 3 184 ? 155.565 134.421 80.830  1.00 70.01  ? 166 PHE   H CA  1 
ATOM   3999 C C   . PHE   C 3 184 ? 155.392 134.028 82.291  1.00 72.17  ? 166 PHE   H C   1 
ATOM   4000 O O   . PHE   C 3 184 ? 156.027 133.085 82.775  1.00 76.83  ? 166 PHE   H O   1 
ATOM   4001 C CB  . PHE   C 3 184 ? 154.450 133.803 79.991  1.00 68.16  ? 166 PHE   H CB  1 
ATOM   4002 C CG  . PHE   C 3 184 ? 154.169 134.547 78.719  1.00 67.92  ? 166 PHE   H CG  1 
ATOM   4003 C CD1 . PHE   C 3 184 ? 155.179 134.795 77.806  1.00 69.99  ? 166 PHE   H CD1 1 
ATOM   4004 C CD2 . PHE   C 3 184 ? 152.890 134.983 78.428  1.00 66.89  ? 166 PHE   H CD2 1 
ATOM   4005 C CE1 . PHE   C 3 184 ? 154.921 135.474 76.633  1.00 67.37  ? 166 PHE   H CE1 1 
ATOM   4006 C CE2 . PHE   C 3 184 ? 152.628 135.664 77.257  1.00 66.59  ? 166 PHE   H CE2 1 
ATOM   4007 C CZ  . PHE   C 3 184 ? 153.643 135.907 76.358  1.00 65.53  ? 166 PHE   H CZ  1 
ATOM   4008 N N   . PRO   C 3 185 ? 154.542 134.748 83.023  1.00 69.63  ? 167 PRO   H N   1 
ATOM   4009 C CA  . PRO   C 3 185 ? 154.267 134.374 84.417  1.00 70.47  ? 167 PRO   H CA  1 
ATOM   4010 C C   . PRO   C 3 185 ? 153.648 132.987 84.512  1.00 70.82  ? 167 PRO   H C   1 
ATOM   4011 O O   . PRO   C 3 185 ? 152.951 132.532 83.603  1.00 74.05  ? 167 PRO   H O   1 
ATOM   4012 C CB  . PRO   C 3 185 ? 153.290 135.452 84.903  1.00 71.62  ? 167 PRO   H CB  1 
ATOM   4013 C CG  . PRO   C 3 185 ? 153.263 136.509 83.871  1.00 72.13  ? 167 PRO   H CG  1 
ATOM   4014 C CD  . PRO   C 3 185 ? 154.034 136.084 82.672  1.00 72.39  ? 167 PRO   H CD  1 
ATOM   4015 N N   . ALA   C 3 186 ? 153.917 132.317 85.629  1.00 69.78  ? 168 ALA   H N   1 
ATOM   4016 C CA  . ALA   C 3 186 ? 153.389 130.980 85.856  1.00 67.99  ? 168 ALA   H CA  1 
ATOM   4017 C C   . ALA   C 3 186 ? 151.869 131.004 85.979  1.00 69.88  ? 168 ALA   H C   1 
ATOM   4018 O O   . ALA   C 3 186 ? 151.284 131.895 86.600  1.00 77.72  ? 168 ALA   H O   1 
ATOM   4019 C CB  . ALA   C 3 186 ? 154.003 130.374 87.117  1.00 67.78  ? 168 ALA   H CB  1 
ATOM   4020 N N   . VAL   C 3 187 ? 151.230 130.007 85.374  1.00 62.44  ? 169 VAL   H N   1 
ATOM   4021 C CA  . VAL   C 3 187 ? 149.785 129.838 85.439  1.00 63.87  ? 169 VAL   H CA  1 
ATOM   4022 C C   . VAL   C 3 187 ? 149.493 128.497 86.094  1.00 76.47  ? 169 VAL   H C   1 
ATOM   4023 O O   . VAL   C 3 187 ? 150.273 127.546 85.978  1.00 83.57  ? 169 VAL   H O   1 
ATOM   4024 C CB  . VAL   C 3 187 ? 149.133 129.923 84.042  1.00 68.73  ? 169 VAL   H CB  1 
ATOM   4025 C CG1 . VAL   C 3 187 ? 147.627 130.110 84.160  1.00 73.47  ? 169 VAL   H CG1 1 
ATOM   4026 C CG2 . VAL   C 3 187 ? 149.757 131.047 83.232  1.00 69.33  ? 169 VAL   H CG2 1 
ATOM   4027 N N   . LEU   C 3 188 ? 148.360 128.423 86.788  1.00 81.84  ? 170 LEU   H N   1 
ATOM   4028 C CA  . LEU   C 3 188 ? 147.957 127.228 87.519  1.00 83.37  ? 170 LEU   H CA  1 
ATOM   4029 C C   . LEU   C 3 188 ? 146.839 126.530 86.756  1.00 85.45  ? 170 LEU   H C   1 
ATOM   4030 O O   . LEU   C 3 188 ? 145.808 127.144 86.460  1.00 83.04  ? 170 LEU   H O   1 
ATOM   4031 C CB  . LEU   C 3 188 ? 147.505 127.582 88.934  1.00 83.20  ? 170 LEU   H CB  1 
ATOM   4032 C CG  . LEU   C 3 188 ? 147.448 126.425 89.930  1.00 83.43  ? 170 LEU   H CG  1 
ATOM   4033 C CD1 . LEU   C 3 188 ? 148.849 126.053 90.386  1.00 83.73  ? 170 LEU   H CD1 1 
ATOM   4034 C CD2 . LEU   C 3 188 ? 146.567 126.783 91.115  1.00 86.18  ? 170 LEU   H CD2 1 
ATOM   4035 N N   . GLN   C 3 189 ? 147.043 125.253 86.442  1.00 89.09  ? 171 GLN   H N   1 
ATOM   4036 C CA  . GLN   C 3 189 ? 146.043 124.476 85.730  1.00 85.03  ? 171 GLN   H CA  1 
ATOM   4037 C C   . GLN   C 3 189 ? 145.001 123.924 86.701  1.00 83.94  ? 171 GLN   H C   1 
ATOM   4038 O O   . GLN   C 3 189 ? 145.203 123.876 87.917  1.00 85.03  ? 171 GLN   H O   1 
ATOM   4039 C CB  . GLN   C 3 189 ? 146.704 123.340 84.950  1.00 74.29  ? 171 GLN   H CB  1 
ATOM   4040 N N   . SER   C 3 190 ? 143.871 123.499 86.145  1.00 79.22  ? 172 SER   H N   1 
ATOM   4041 C CA  . SER   C 3 190 ? 142.781 122.956 86.950  1.00 81.47  ? 172 SER   H CA  1 
ATOM   4042 C C   . SER   C 3 190 ? 143.129 121.569 87.480  1.00 84.65  ? 172 SER   H C   1 
ATOM   4043 O O   . SER   C 3 190 ? 142.357 120.969 88.228  1.00 86.33  ? 172 SER   H O   1 
ATOM   4044 C CB  . SER   C 3 190 ? 141.488 122.898 86.134  1.00 83.01  ? 172 SER   H CB  1 
ATOM   4045 N N   . SER   C 3 195 ? 152.088 126.045 84.610  1.00 70.83  ? 177 SER   H N   1 
ATOM   4046 C CA  . SER   C 3 195 ? 152.161 126.044 83.154  1.00 75.10  ? 177 SER   H CA  1 
ATOM   4047 C C   . SER   C 3 195 ? 152.637 127.392 82.623  1.00 77.02  ? 177 SER   H C   1 
ATOM   4048 O O   . SER   C 3 195 ? 151.879 128.361 82.601  1.00 78.12  ? 177 SER   H O   1 
ATOM   4049 C CB  . SER   C 3 195 ? 150.801 125.699 82.549  1.00 73.06  ? 177 SER   H CB  1 
ATOM   4050 O OG  . SER   C 3 195 ? 150.022 126.866 82.358  1.00 72.17  ? 177 SER   H OG  1 
ATOM   4051 N N   . LEU   C 3 196 ? 153.894 127.443 82.190  1.00 76.52  ? 178 LEU   H N   1 
ATOM   4052 C CA  . LEU   C 3 196 ? 154.488 128.662 81.665  1.00 76.28  ? 178 LEU   H CA  1 
ATOM   4053 C C   . LEU   C 3 196 ? 155.110 128.373 80.308  1.00 74.89  ? 178 LEU   H C   1 
ATOM   4054 O O   . LEU   C 3 196 ? 155.613 127.275 80.059  1.00 78.32  ? 178 LEU   H O   1 
ATOM   4055 C CB  . LEU   C 3 196 ? 155.540 129.235 82.627  1.00 77.61  ? 178 LEU   H CB  1 
ATOM   4056 C CG  . LEU   C 3 196 ? 156.797 128.401 82.883  1.00 76.96  ? 178 LEU   H CG  1 
ATOM   4057 C CD1 . LEU   C 3 196 ? 157.974 128.910 82.061  1.00 75.99  ? 178 LEU   H CD1 1 
ATOM   4058 C CD2 . LEU   C 3 196 ? 157.138 128.388 84.365  1.00 74.96  ? 178 LEU   H CD2 1 
ATOM   4059 N N   . SER   C 3 197 ? 155.070 129.373 79.431  1.00 71.35  ? 179 SER   H N   1 
ATOM   4060 C CA  . SER   C 3 197 ? 155.585 129.257 78.074  1.00 76.21  ? 179 SER   H CA  1 
ATOM   4061 C C   . SER   C 3 197 ? 156.662 130.307 77.847  1.00 79.69  ? 179 SER   H C   1 
ATOM   4062 O O   . SER   C 3 197 ? 156.462 131.484 78.161  1.00 84.21  ? 179 SER   H O   1 
ATOM   4063 C CB  . SER   C 3 197 ? 154.463 129.414 77.044  1.00 70.78  ? 179 SER   H CB  1 
ATOM   4064 O OG  . SER   C 3 197 ? 153.472 130.317 77.500  1.00 69.39  ? 179 SER   H OG  1 
ATOM   4065 N N   . SER   C 3 198 ? 157.798 129.877 77.302  1.00 80.91  ? 180 SER   H N   1 
ATOM   4066 C CA  . SER   C 3 198 ? 158.919 130.758 76.999  1.00 83.82  ? 180 SER   H CA  1 
ATOM   4067 C C   . SER   C 3 198 ? 159.100 130.808 75.489  1.00 91.41  ? 180 SER   H C   1 
ATOM   4068 O O   . SER   C 3 198 ? 159.241 129.764 74.844  1.00 94.12  ? 180 SER   H O   1 
ATOM   4069 C CB  . SER   C 3 198 ? 160.200 130.274 77.682  1.00 80.17  ? 180 SER   H CB  1 
ATOM   4070 N N   . VAL   C 3 199 ? 159.097 132.016 74.932  1.00 93.87  ? 181 VAL   H N   1 
ATOM   4071 C CA  . VAL   C 3 199 ? 159.217 132.229 73.495  1.00 97.37  ? 181 VAL   H CA  1 
ATOM   4072 C C   . VAL   C 3 199 ? 160.350 133.215 73.243  1.00 101.27 ? 181 VAL   H C   1 
ATOM   4073 O O   . VAL   C 3 199 ? 160.460 134.233 73.936  1.00 100.09 ? 181 VAL   H O   1 
ATOM   4074 C CB  . VAL   C 3 199 ? 157.897 132.734 72.883  1.00 92.54  ? 181 VAL   H CB  1 
ATOM   4075 C CG1 . VAL   C 3 199 ? 156.881 131.606 72.820  1.00 89.63  ? 181 VAL   H CG1 1 
ATOM   4076 C CG2 . VAL   C 3 199 ? 157.342 133.895 73.692  1.00 91.68  ? 181 VAL   H CG2 1 
ATOM   4077 N N   . VAL   C 3 200 ? 161.195 132.904 72.264  1.00 103.77 ? 182 VAL   H N   1 
ATOM   4078 C CA  . VAL   C 3 200 ? 162.320 133.750 71.883  1.00 106.85 ? 182 VAL   H CA  1 
ATOM   4079 C C   . VAL   C 3 200 ? 162.182 134.094 70.407  1.00 112.63 ? 182 VAL   H C   1 
ATOM   4080 O O   . VAL   C 3 200 ? 162.239 133.206 69.549  1.00 111.10 ? 182 VAL   H O   1 
ATOM   4081 C CB  . VAL   C 3 200 ? 163.669 133.062 72.160  1.00 107.49 ? 182 VAL   H CB  1 
ATOM   4082 N N   . THR   C 3 201 ? 162.013 135.380 70.115  1.00 119.32 ? 183 THR   H N   1 
ATOM   4083 C CA  . THR   C 3 201 ? 161.853 135.834 68.739  1.00 121.01 ? 183 THR   H CA  1 
ATOM   4084 C C   . THR   C 3 201 ? 163.190 136.254 68.139  1.00 119.52 ? 183 THR   H C   1 
ATOM   4085 O O   . THR   C 3 201 ? 163.842 137.173 68.635  1.00 111.14 ? 183 THR   H O   1 
ATOM   4086 C CB  . THR   C 3 201 ? 160.865 137.011 68.645  1.00 114.02 ? 183 THR   H CB  1 
ATOM   4087 O OG1 . THR   C 3 201 ? 159.584 136.604 69.139  1.00 108.30 ? 183 THR   H OG1 1 
ATOM   4088 C CG2 . THR   C 3 201 ? 160.724 137.472 67.202  1.00 114.77 ? 183 THR   H CG2 1 
ATOM   4089 N N   . TYR   C 3 212 ? 169.858 127.241 68.799  1.00 127.54 ? 194 TYR   H N   1 
ATOM   4090 C CA  . TYR   C 3 212 ? 169.264 127.742 70.033  1.00 128.30 ? 194 TYR   H CA  1 
ATOM   4091 C C   . TYR   C 3 212 ? 168.754 126.593 70.895  1.00 131.45 ? 194 TYR   H C   1 
ATOM   4092 O O   . TYR   C 3 212 ? 167.914 125.804 70.463  1.00 133.58 ? 194 TYR   H O   1 
ATOM   4093 C CB  . TYR   C 3 212 ? 168.127 128.718 69.725  1.00 125.45 ? 194 TYR   H CB  1 
ATOM   4094 C CG  . TYR   C 3 212 ? 168.465 129.729 68.653  1.00 121.97 ? 194 TYR   H CG  1 
ATOM   4095 C CD1 . TYR   C 3 212 ? 169.158 130.893 68.963  1.00 123.42 ? 194 TYR   H CD1 1 
ATOM   4096 C CD2 . TYR   C 3 212 ? 168.092 129.522 67.332  1.00 117.52 ? 194 TYR   H CD2 1 
ATOM   4097 C CE1 . TYR   C 3 212 ? 169.469 131.820 67.987  1.00 123.69 ? 194 TYR   H CE1 1 
ATOM   4098 C CE2 . TYR   C 3 212 ? 168.399 130.443 66.349  1.00 114.72 ? 194 TYR   H CE2 1 
ATOM   4099 C CZ  . TYR   C 3 212 ? 169.087 131.591 66.682  1.00 119.36 ? 194 TYR   H CZ  1 
ATOM   4100 O OH  . TYR   C 3 212 ? 169.395 132.511 65.707  1.00 117.04 ? 194 TYR   H OH  1 
ATOM   4101 N N   . ILE   C 3 213 ? 169.269 126.505 72.119  1.00 131.10 ? 195 ILE   H N   1 
ATOM   4102 C CA  . ILE   C 3 213 ? 168.919 125.445 73.057  1.00 132.88 ? 195 ILE   H CA  1 
ATOM   4103 C C   . ILE   C 3 213 ? 168.296 126.081 74.290  1.00 129.82 ? 195 ILE   H C   1 
ATOM   4104 O O   . ILE   C 3 213 ? 168.863 127.017 74.866  1.00 127.37 ? 195 ILE   H O   1 
ATOM   4105 C CB  . ILE   C 3 213 ? 170.146 124.598 73.444  1.00 134.35 ? 195 ILE   H CB  1 
ATOM   4106 C CG1 . ILE   C 3 213 ? 171.021 124.329 72.217  1.00 132.92 ? 195 ILE   H CG1 1 
ATOM   4107 C CG2 . ILE   C 3 213 ? 169.709 123.293 74.091  1.00 133.01 ? 195 ILE   H CG2 1 
ATOM   4108 C CD1 . ILE   C 3 213 ? 172.312 123.607 72.535  1.00 131.40 ? 195 ILE   H CD1 1 
ATOM   4109 N N   . CYS   C 3 214 ? 167.134 125.575 74.692  1.00 131.11 ? 196 CYS   H N   1 
ATOM   4110 C CA  . CYS   C 3 214 ? 166.454 126.032 75.897  1.00 129.26 ? 196 CYS   H CA  1 
ATOM   4111 C C   . CYS   C 3 214 ? 166.753 125.054 77.027  1.00 128.96 ? 196 CYS   H C   1 
ATOM   4112 O O   . CYS   C 3 214 ? 166.705 123.835 76.831  1.00 127.88 ? 196 CYS   H O   1 
ATOM   4113 C CB  . CYS   C 3 214 ? 164.946 126.161 75.664  1.00 128.94 ? 196 CYS   H CB  1 
ATOM   4114 S SG  . CYS   C 3 214 ? 164.016 124.606 75.644  1.00 121.94 ? 196 CYS   H SG  1 
ATOM   4115 N N   . ASN   C 3 215 ? 167.090 125.590 78.197  1.00 125.89 ? 197 ASN   H N   1 
ATOM   4116 C CA  . ASN   C 3 215 ? 167.393 124.789 79.376  1.00 124.40 ? 197 ASN   H CA  1 
ATOM   4117 C C   . ASN   C 3 215 ? 166.370 125.107 80.457  1.00 118.50 ? 197 ASN   H C   1 
ATOM   4118 O O   . ASN   C 3 215 ? 166.237 126.265 80.868  1.00 116.08 ? 197 ASN   H O   1 
ATOM   4119 C CB  . ASN   C 3 215 ? 168.812 125.063 79.874  1.00 126.23 ? 197 ASN   H CB  1 
ATOM   4120 C CG  . ASN   C 3 215 ? 169.871 124.643 78.875  1.00 130.69 ? 197 ASN   H CG  1 
ATOM   4121 O OD1 . ASN   C 3 215 ? 169.771 123.584 78.255  1.00 133.47 ? 197 ASN   H OD1 1 
ATOM   4122 N ND2 . ASN   C 3 215 ? 170.894 125.473 78.713  1.00 126.56 ? 197 ASN   H ND2 1 
ATOM   4123 N N   . VAL   C 3 216 ? 165.659 124.083 80.917  1.00 116.74 ? 198 VAL   H N   1 
ATOM   4124 C CA  . VAL   C 3 216 ? 164.605 124.227 81.915  1.00 114.05 ? 198 VAL   H CA  1 
ATOM   4125 C C   . VAL   C 3 216 ? 165.048 123.493 83.173  1.00 115.67 ? 198 VAL   H C   1 
ATOM   4126 O O   . VAL   C 3 216 ? 165.409 122.311 83.116  1.00 118.19 ? 198 VAL   H O   1 
ATOM   4127 C CB  . VAL   C 3 216 ? 163.261 123.687 81.403  1.00 108.90 ? 198 VAL   H CB  1 
ATOM   4128 C CG1 . VAL   C 3 216 ? 162.225 123.713 82.514  1.00 104.89 ? 198 VAL   H CG1 1 
ATOM   4129 C CG2 . VAL   C 3 216 ? 162.784 124.488 80.198  1.00 108.28 ? 198 VAL   H CG2 1 
ATOM   4130 N N   . ASN   C 3 217 ? 165.024 124.189 84.308  1.00 112.34 ? 199 ASN   H N   1 
ATOM   4131 C CA  . ASN   C 3 217 ? 165.478 123.637 85.579  1.00 114.52 ? 199 ASN   H CA  1 
ATOM   4132 C C   . ASN   C 3 217 ? 164.384 123.798 86.623  1.00 111.15 ? 199 ASN   H C   1 
ATOM   4133 O O   . ASN   C 3 217 ? 163.874 124.905 86.831  1.00 108.51 ? 199 ASN   H O   1 
ATOM   4134 C CB  . ASN   C 3 217 ? 166.768 124.317 86.042  1.00 117.16 ? 199 ASN   H CB  1 
ATOM   4135 C CG  . ASN   C 3 217 ? 167.956 123.368 86.066  1.00 119.17 ? 199 ASN   H CG  1 
ATOM   4136 O OD1 . ASN   C 3 217 ? 168.028 122.415 85.286  1.00 119.71 ? 199 ASN   H OD1 1 
ATOM   4137 N ND2 . ASN   C 3 217 ? 168.895 123.626 86.969  1.00 115.33 ? 199 ASN   H ND2 1 
ATOM   4138 N N   . HIS   C 3 218 ? 164.027 122.694 87.275  1.00 109.02 ? 200 HIS   H N   1 
ATOM   4139 C CA  . HIS   C 3 218 ? 163.084 122.696 88.386  1.00 107.21 ? 200 HIS   H CA  1 
ATOM   4140 C C   . HIS   C 3 218 ? 163.856 122.334 89.650  1.00 109.08 ? 200 HIS   H C   1 
ATOM   4141 O O   . HIS   C 3 218 ? 164.270 121.183 89.823  1.00 111.24 ? 200 HIS   H O   1 
ATOM   4142 C CB  . HIS   C 3 218 ? 161.941 121.716 88.133  1.00 106.14 ? 200 HIS   H CB  1 
ATOM   4143 C CG  . HIS   C 3 218 ? 160.812 121.841 89.108  1.00 107.19 ? 200 HIS   H CG  1 
ATOM   4144 N ND1 . HIS   C 3 218 ? 160.415 123.051 89.633  1.00 105.60 ? 200 HIS   H ND1 1 
ATOM   4145 C CD2 . HIS   C 3 218 ? 159.992 120.909 89.649  1.00 106.61 ? 200 HIS   H CD2 1 
ATOM   4146 C CE1 . HIS   C 3 218 ? 159.401 122.860 90.457  1.00 102.20 ? 200 HIS   H CE1 1 
ATOM   4147 N NE2 . HIS   C 3 218 ? 159.125 121.569 90.485  1.00 103.62 ? 200 HIS   H NE2 1 
ATOM   4148 N N   . LYS   C 3 219 ? 164.058 123.320 90.523  1.00 107.71 ? 201 LYS   H N   1 
ATOM   4149 C CA  . LYS   C 3 219 ? 164.861 123.092 91.721  1.00 108.82 ? 201 LYS   H CA  1 
ATOM   4150 C C   . LYS   C 3 219 ? 164.290 122.025 92.652  1.00 109.47 ? 201 LYS   H C   1 
ATOM   4151 O O   . LYS   C 3 219 ? 165.070 121.164 93.098  1.00 108.72 ? 201 LYS   H O   1 
ATOM   4152 C CB  . LYS   C 3 219 ? 165.062 124.418 92.468  1.00 106.92 ? 201 LYS   H CB  1 
ATOM   4153 N N   . PRO   C 3 220 ? 162.995 122.017 93.001  1.00 109.31 ? 202 PRO   H N   1 
ATOM   4154 C CA  . PRO   C 3 220 ? 162.504 120.956 93.900  1.00 106.72 ? 202 PRO   H CA  1 
ATOM   4155 C C   . PRO   C 3 220 ? 162.702 119.551 93.358  1.00 106.45 ? 202 PRO   H C   1 
ATOM   4156 O O   . PRO   C 3 220 ? 162.998 118.632 94.131  1.00 104.48 ? 202 PRO   H O   1 
ATOM   4157 C CB  . PRO   C 3 220 ? 161.016 121.297 94.056  1.00 102.38 ? 202 PRO   H CB  1 
ATOM   4158 C CG  . PRO   C 3 220 ? 160.944 122.756 93.823  1.00 107.02 ? 202 PRO   H CG  1 
ATOM   4159 C CD  . PRO   C 3 220 ? 161.949 123.025 92.742  1.00 107.83 ? 202 PRO   H CD  1 
ATOM   4160 N N   . SER   C 3 221 ? 162.546 119.355 92.052  1.00 108.58 ? 203 SER   H N   1 
ATOM   4161 C CA  . SER   C 3 221 ? 162.666 118.034 91.452  1.00 109.80 ? 203 SER   H CA  1 
ATOM   4162 C C   . SER   C 3 221 ? 164.061 117.742 90.917  1.00 111.84 ? 203 SER   H C   1 
ATOM   4163 O O   . SER   C 3 221 ? 164.331 116.597 90.540  1.00 113.83 ? 203 SER   H O   1 
ATOM   4164 C CB  . SER   C 3 221 ? 161.643 117.874 90.322  1.00 103.92 ? 203 SER   H CB  1 
ATOM   4165 N N   . ASN   C 3 222 ? 164.948 118.739 90.885  1.00 111.76 ? 204 ASN   H N   1 
ATOM   4166 C CA  . ASN   C 3 222 ? 166.291 118.585 90.321  1.00 115.11 ? 204 ASN   H CA  1 
ATOM   4167 C C   . ASN   C 3 222 ? 166.233 118.032 88.898  1.00 116.01 ? 204 ASN   H C   1 
ATOM   4168 O O   . ASN   C 3 222 ? 167.019 117.162 88.518  1.00 118.55 ? 204 ASN   H O   1 
ATOM   4169 C CB  . ASN   C 3 222 ? 167.171 117.705 91.212  1.00 112.68 ? 204 ASN   H CB  1 
ATOM   4170 N N   . THR   C 3 223 ? 165.293 118.538 88.105  1.00 114.64 ? 205 THR   H N   1 
ATOM   4171 C CA  . THR   C 3 223 ? 165.072 118.060 86.745  1.00 117.77 ? 205 THR   H CA  1 
ATOM   4172 C C   . THR   C 3 223 ? 165.762 119.000 85.764  1.00 120.47 ? 205 THR   H C   1 
ATOM   4173 O O   . THR   C 3 223 ? 165.494 120.207 85.759  1.00 116.95 ? 205 THR   H O   1 
ATOM   4174 C CB  . THR   C 3 223 ? 163.578 117.959 86.436  1.00 114.69 ? 205 THR   H CB  1 
ATOM   4175 O OG1 . THR   C 3 223 ? 162.967 117.014 87.324  1.00 111.03 ? 205 THR   H OG1 1 
ATOM   4176 C CG2 . THR   C 3 223 ? 163.360 117.509 84.998  1.00 110.05 ? 205 THR   H CG2 1 
ATOM   4177 N N   . LYS   C 3 224 ? 166.650 118.447 84.943  1.00 122.63 ? 206 LYS   H N   1 
ATOM   4178 C CA  . LYS   C 3 224 ? 167.409 119.216 83.967  1.00 119.23 ? 206 LYS   H CA  1 
ATOM   4179 C C   . LYS   C 3 224 ? 167.183 118.629 82.583  1.00 118.07 ? 206 LYS   H C   1 
ATOM   4180 O O   . LYS   C 3 224 ? 167.342 117.420 82.383  1.00 117.29 ? 206 LYS   H O   1 
ATOM   4181 C CB  . LYS   C 3 224 ? 168.903 119.214 84.310  1.00 117.96 ? 206 LYS   H CB  1 
ATOM   4182 N N   . VAL   C 3 225 ? 166.807 119.482 81.634  1.00 117.50 ? 207 VAL   H N   1 
ATOM   4183 C CA  . VAL   C 3 225 ? 166.603 119.044 80.258  1.00 118.32 ? 207 VAL   H CA  1 
ATOM   4184 C C   . VAL   C 3 225 ? 167.380 119.944 79.304  1.00 119.23 ? 207 VAL   H C   1 
ATOM   4185 O O   . VAL   C 3 225 ? 167.213 121.164 79.311  1.00 119.47 ? 207 VAL   H O   1 
ATOM   4186 C CB  . VAL   C 3 225 ? 165.109 119.018 79.881  1.00 114.71 ? 207 VAL   H CB  1 
ATOM   4187 C CG1 . VAL   C 3 225 ? 164.942 118.600 78.428  1.00 112.43 ? 207 VAL   H CG1 1 
ATOM   4188 C CG2 . VAL   C 3 225 ? 164.335 118.079 80.797  1.00 111.77 ? 207 VAL   H CG2 1 
ATOM   4189 N N   . LYS   C 3 228 ? 167.661 121.175 71.805  1.00 141.32 ? 210 LYS   H N   1 
ATOM   4190 C CA  . LYS   C 3 228 ? 167.717 122.229 70.799  1.00 139.00 ? 210 LYS   H CA  1 
ATOM   4191 C C   . LYS   C 3 228 ? 166.402 122.326 70.033  1.00 140.29 ? 210 LYS   H C   1 
ATOM   4192 O O   . LYS   C 3 228 ? 165.715 121.324 69.830  1.00 141.61 ? 210 LYS   H O   1 
ATOM   4193 C CB  . LYS   C 3 228 ? 168.874 121.983 69.828  1.00 136.46 ? 210 LYS   H CB  1 
ATOM   4194 N N   . VAL   C 3 229 ? 166.056 123.538 69.610  1.00 140.07 ? 211 VAL   H N   1 
ATOM   4195 C CA  . VAL   C 3 229 ? 164.836 123.799 68.855  1.00 139.93 ? 211 VAL   H CA  1 
ATOM   4196 C C   . VAL   C 3 229 ? 165.235 124.173 67.435  1.00 139.41 ? 211 VAL   H C   1 
ATOM   4197 O O   . VAL   C 3 229 ? 165.938 125.169 67.220  1.00 136.35 ? 211 VAL   H O   1 
ATOM   4198 C CB  . VAL   C 3 229 ? 163.993 124.908 69.503  1.00 137.64 ? 211 VAL   H CB  1 
ATOM   4199 C CG1 . VAL   C 3 229 ? 162.606 124.950 68.881  1.00 130.62 ? 211 VAL   H CG1 1 
ATOM   4200 C CG2 . VAL   C 3 229 ? 163.903 124.695 71.006  1.00 132.99 ? 211 VAL   H CG2 1 
ATOM   4201 N N   . GLU   C 3 230 ? 164.788 123.378 66.470  1.00 141.39 ? 212 GLU   H N   1 
ATOM   4202 C CA  . GLU   C 3 230 ? 165.096 123.605 65.066  1.00 143.64 ? 212 GLU   H CA  1 
ATOM   4203 C C   . GLU   C 3 230 ? 163.837 123.356 64.254  1.00 144.71 ? 212 GLU   H C   1 
ATOM   4204 O O   . GLU   C 3 230 ? 162.970 122.576 64.668  1.00 139.84 ? 212 GLU   H O   1 
ATOM   4205 C CB  . GLU   C 3 230 ? 166.234 122.693 64.589  1.00 142.63 ? 212 GLU   H CB  1 
ATOM   4206 N N   . PRO   C 3 231 ? 163.696 124.012 63.090  1.00 148.44 ? 213 PRO   H N   1 
ATOM   4207 C CA  . PRO   C 3 231 ? 162.550 123.807 62.197  1.00 148.21 ? 213 PRO   H CA  1 
ATOM   4208 C C   . PRO   C 3 231 ? 162.396 122.354 61.754  1.00 147.40 ? 213 PRO   H C   1 
ATOM   4209 O O   . PRO   C 3 231 ? 161.568 121.642 62.321  1.00 146.23 ? 213 PRO   H O   1 
ATOM   4210 C CB  . PRO   C 3 231 ? 162.877 124.702 60.999  1.00 144.97 ? 213 PRO   H CB  1 
ATOM   4211 C CG  . PRO   C 3 231 ? 163.739 125.773 61.558  1.00 145.53 ? 213 PRO   H CG  1 
ATOM   4212 C CD  . PRO   C 3 231 ? 164.556 125.121 62.637  1.00 145.79 ? 213 PRO   H CD  1 
ATOM   4213 N N   . THR   D 4 6   ? 135.441 151.235 96.560  1.00 33.41  ? 5   THR   L N   1 
ATOM   4214 C CA  . THR   D 4 6   ? 135.103 151.133 95.145  1.00 38.30  ? 5   THR   L CA  1 
ATOM   4215 C C   . THR   D 4 6   ? 135.908 152.126 94.317  1.00 39.20  ? 5   THR   L C   1 
ATOM   4216 O O   . THR   D 4 6   ? 135.428 153.213 93.994  1.00 38.50  ? 5   THR   L O   1 
ATOM   4217 C CB  . THR   D 4 6   ? 133.602 151.376 94.902  1.00 41.14  ? 5   THR   L CB  1 
ATOM   4218 N N   . GLN   D 4 7   ? 137.135 151.746 93.975  1.00 35.40  ? 6   GLN   L N   1 
ATOM   4219 C CA  . GLN   D 4 7   ? 138.011 152.603 93.186  1.00 32.30  ? 6   GLN   L CA  1 
ATOM   4220 C C   . GLN   D 4 7   ? 137.593 152.617 91.721  1.00 35.40  ? 6   GLN   L C   1 
ATOM   4221 O O   . GLN   D 4 7   ? 138.055 151.798 90.928  1.00 39.74  ? 6   GLN   L O   1 
ATOM   4222 C CB  . GLN   D 4 7   ? 139.465 152.147 93.313  1.00 26.65  ? 6   GLN   L CB  1 
ATOM   4223 C CG  . GLN   D 4 7   ? 139.932 151.954 94.745  1.00 20.41  ? 6   GLN   L CG  1 
ATOM   4224 C CD  . GLN   D 4 7   ? 141.439 151.856 94.859  1.00 16.95  ? 6   GLN   L CD  1 
ATOM   4225 O OE1 . GLN   D 4 7   ? 142.173 152.485 94.098  1.00 16.29  ? 6   GLN   L OE1 1 
ATOM   4226 N NE2 . GLN   D 4 7   ? 141.909 151.066 95.814  1.00 15.66  ? 6   GLN   L NE2 1 
ATOM   4227 N N   . SER   D 4 10  ? 139.744 151.242 86.909  1.00 47.49  ? 9   SER   L N   1 
ATOM   4228 C CA  . SER   D 4 10  ? 140.549 150.219 87.567  1.00 33.69  ? 9   SER   L CA  1 
ATOM   4229 C C   . SER   D 4 10  ? 142.012 150.320 87.146  1.00 34.31  ? 9   SER   L C   1 
ATOM   4230 O O   . SER   D 4 10  ? 142.916 150.077 87.944  1.00 29.39  ? 9   SER   L O   1 
ATOM   4231 C CB  . SER   D 4 10  ? 140.004 148.826 87.252  1.00 31.58  ? 9   SER   L CB  1 
ATOM   4232 N N   . SER   D 4 11  ? 142.235 150.676 85.884  1.00 38.97  ? 10  SER   L N   1 
ATOM   4233 C CA  . SER   D 4 11  ? 143.574 150.838 85.338  1.00 37.97  ? 10  SER   L CA  1 
ATOM   4234 C C   . SER   D 4 11  ? 143.707 152.231 84.743  1.00 41.73  ? 10  SER   L C   1 
ATOM   4235 O O   . SER   D 4 11  ? 142.820 152.694 84.021  1.00 42.70  ? 10  SER   L O   1 
ATOM   4236 C CB  . SER   D 4 11  ? 143.875 149.779 84.270  1.00 35.19  ? 10  SER   L CB  1 
ATOM   4237 O OG  . SER   D 4 11  ? 145.144 149.995 83.678  1.00 40.27  ? 10  SER   L OG  1 
ATOM   4238 N N   . LEU   D 4 12  ? 144.818 152.895 85.052  1.00 46.02  ? 11  LEU   L N   1 
ATOM   4239 C CA  . LEU   D 4 12  ? 145.089 154.243 84.569  1.00 53.52  ? 11  LEU   L CA  1 
ATOM   4240 C C   . LEU   D 4 12  ? 146.375 154.235 83.759  1.00 58.88  ? 11  LEU   L C   1 
ATOM   4241 O O   . LEU   D 4 12  ? 147.320 153.515 84.096  1.00 56.97  ? 11  LEU   L O   1 
ATOM   4242 C CB  . LEU   D 4 12  ? 145.202 155.243 85.726  1.00 46.65  ? 11  LEU   L CB  1 
ATOM   4243 C CG  . LEU   D 4 12  ? 143.977 156.096 86.068  1.00 41.91  ? 11  LEU   L CG  1 
ATOM   4244 C CD1 . LEU   D 4 12  ? 142.702 155.267 86.084  1.00 52.06  ? 11  LEU   L CD1 1 
ATOM   4245 C CD2 . LEU   D 4 12  ? 144.176 156.801 87.400  1.00 30.41  ? 11  LEU   L CD2 1 
ATOM   4246 N N   . SER   D 4 13  ? 146.400 155.019 82.688  1.00 62.47  ? 12  SER   L N   1 
ATOM   4247 C CA  . SER   D 4 13  ? 147.587 155.197 81.863  1.00 58.14  ? 12  SER   L CA  1 
ATOM   4248 C C   . SER   D 4 13  ? 147.948 156.676 81.848  1.00 58.19  ? 12  SER   L C   1 
ATOM   4249 O O   . SER   D 4 13  ? 147.108 157.519 81.515  1.00 60.30  ? 12  SER   L O   1 
ATOM   4250 C CB  . SER   D 4 13  ? 147.352 154.680 80.444  1.00 56.01  ? 12  SER   L CB  1 
ATOM   4251 N N   . ALA   D 4 14  ? 149.190 156.987 82.210  1.00 61.28  ? 13  ALA   L N   1 
ATOM   4252 C CA  . ALA   D 4 14  ? 149.656 158.365 82.234  1.00 61.42  ? 13  ALA   L CA  1 
ATOM   4253 C C   . ALA   D 4 14  ? 151.172 158.383 82.126  1.00 63.01  ? 13  ALA   L C   1 
ATOM   4254 O O   . ALA   D 4 14  ? 151.852 157.528 82.700  1.00 59.88  ? 13  ALA   L O   1 
ATOM   4255 C CB  . ALA   D 4 14  ? 149.206 159.086 83.509  1.00 55.23  ? 13  ALA   L CB  1 
ATOM   4256 N N   . SER   D 4 15  ? 151.691 159.362 81.394  1.00 65.39  ? 14  SER   L N   1 
ATOM   4257 C CA  . SER   D 4 15  ? 153.125 159.511 81.203  1.00 62.48  ? 14  SER   L CA  1 
ATOM   4258 C C   . SER   D 4 15  ? 153.763 160.171 82.421  1.00 59.68  ? 14  SER   L C   1 
ATOM   4259 O O   . SER   D 4 15  ? 153.082 160.703 83.301  1.00 57.80  ? 14  SER   L O   1 
ATOM   4260 C CB  . SER   D 4 15  ? 153.417 160.333 79.947  1.00 64.00  ? 14  SER   L CB  1 
ATOM   4261 O OG  . SER   D 4 15  ? 152.465 160.070 78.931  1.00 65.01  ? 14  SER   L OG  1 
ATOM   4262 N N   . VAL   D 4 16  ? 155.097 160.124 82.462  1.00 59.24  ? 15  VAL   L N   1 
ATOM   4263 C CA  . VAL   D 4 16  ? 155.826 160.736 83.565  1.00 55.55  ? 15  VAL   L CA  1 
ATOM   4264 C C   . VAL   D 4 16  ? 155.625 162.243 83.532  1.00 55.93  ? 15  VAL   L C   1 
ATOM   4265 O O   . VAL   D 4 16  ? 155.796 162.894 82.494  1.00 61.23  ? 15  VAL   L O   1 
ATOM   4266 C CB  . VAL   D 4 16  ? 157.318 160.370 83.492  1.00 53.20  ? 15  VAL   L CB  1 
ATOM   4267 C CG1 . VAL   D 4 16  ? 158.127 161.221 84.459  1.00 51.62  ? 15  VAL   L CG1 1 
ATOM   4268 C CG2 . VAL   D 4 16  ? 157.517 158.892 83.784  1.00 56.32  ? 15  VAL   L CG2 1 
ATOM   4269 N N   . GLY   D 4 17  ? 155.255 162.807 84.679  1.00 57.32  ? 16  GLY   L N   1 
ATOM   4270 C CA  . GLY   D 4 17  ? 154.982 164.223 84.777  1.00 60.10  ? 16  GLY   L CA  1 
ATOM   4271 C C   . GLY   D 4 17  ? 153.548 164.621 84.508  1.00 64.02  ? 16  GLY   L C   1 
ATOM   4272 O O   . GLY   D 4 17  ? 153.273 165.819 84.365  1.00 63.92  ? 16  GLY   L O   1 
ATOM   4273 N N   . ASP   D 4 18  ? 152.627 163.667 84.436  1.00 63.93  ? 17  ASP   L N   1 
ATOM   4274 C CA  . ASP   D 4 18  ? 151.219 163.951 84.196  1.00 63.65  ? 17  ASP   L CA  1 
ATOM   4275 C C   . ASP   D 4 18  ? 150.497 163.951 85.537  1.00 59.71  ? 17  ASP   L C   1 
ATOM   4276 O O   . ASP   D 4 18  ? 150.779 163.111 86.400  1.00 56.19  ? 17  ASP   L O   1 
ATOM   4277 C CB  . ASP   D 4 18  ? 150.609 162.916 83.245  1.00 63.66  ? 17  ASP   L CB  1 
ATOM   4278 C CG  . ASP   D 4 18  ? 149.094 163.027 83.126  1.00 64.89  ? 17  ASP   L CG  1 
ATOM   4279 O OD1 . ASP   D 4 18  ? 148.499 164.022 83.597  1.00 58.69  ? 17  ASP   L OD1 1 
ATOM   4280 O OD2 . ASP   D 4 18  ? 148.490 162.123 82.510  1.00 67.77  ? 17  ASP   L OD2 1 
ATOM   4281 N N   . ARG   D 4 19  ? 149.577 164.893 85.709  1.00 60.71  ? 18  ARG   L N   1 
ATOM   4282 C CA  . ARG   D 4 19  ? 148.895 165.065 86.983  1.00 57.79  ? 18  ARG   L CA  1 
ATOM   4283 C C   . ARG   D 4 19  ? 147.877 163.950 87.219  1.00 57.33  ? 18  ARG   L C   1 
ATOM   4284 O O   . ARG   D 4 19  ? 147.109 163.603 86.329  1.00 59.01  ? 18  ARG   L O   1 
ATOM   4285 C CB  . ARG   D 4 19  ? 148.200 166.426 87.038  1.00 58.64  ? 18  ARG   L CB  1 
ATOM   4286 C CG  . ARG   D 4 19  ? 147.010 166.485 87.973  1.00 53.08  ? 18  ARG   L CG  1 
ATOM   4287 C CD  . ARG   D 4 19  ? 146.639 167.922 88.276  1.00 54.12  ? 18  ARG   L CD  1 
ATOM   4288 N NE  . ARG   D 4 19  ? 147.754 168.631 88.897  1.00 58.96  ? 18  ARG   L NE  1 
ATOM   4289 C CZ  . ARG   D 4 19  ? 148.151 168.464 90.154  1.00 56.72  ? 18  ARG   L CZ  1 
ATOM   4290 N NH1 . ARG   D 4 19  ? 147.535 167.623 90.967  1.00 50.03  ? 18  ARG   L NH1 1 
ATOM   4291 N NH2 . ARG   D 4 19  ? 149.195 169.160 90.606  1.00 61.14  ? 18  ARG   L NH2 1 
ATOM   4292 N N   . THR   D 4 21  ? 144.842 161.518 89.312  1.00 23.34  ? 20  THR   L N   1 
ATOM   4293 C CA  . THR   D 4 21  ? 143.613 161.833 90.030  1.00 20.27  ? 20  THR   L CA  1 
ATOM   4294 C C   . THR   D 4 21  ? 142.798 160.574 90.309  1.00 17.72  ? 20  THR   L C   1 
ATOM   4295 O O   . THR   D 4 21  ? 141.757 160.348 89.692  1.00 17.80  ? 20  THR   L O   1 
ATOM   4296 C CB  . THR   D 4 21  ? 142.744 162.831 89.248  1.00 21.56  ? 20  THR   L CB  1 
ATOM   4297 N N   . ILE   D 4 22  ? 143.279 159.762 91.245  1.00 14.72  ? 21  ILE   L N   1 
ATOM   4298 C CA  . ILE   D 4 22  ? 142.621 158.516 91.607  1.00 14.68  ? 21  ILE   L CA  1 
ATOM   4299 C C   . ILE   D 4 22  ? 141.393 158.829 92.452  1.00 17.30  ? 21  ILE   L C   1 
ATOM   4300 O O   . ILE   D 4 22  ? 141.265 159.909 93.030  1.00 24.50  ? 21  ILE   L O   1 
ATOM   4301 C CB  . ILE   D 4 22  ? 143.592 157.578 92.349  1.00 12.85  ? 21  ILE   L CB  1 
ATOM   4302 C CG1 . ILE   D 4 22  ? 144.976 157.654 91.708  1.00 13.78  ? 21  ILE   L CG1 1 
ATOM   4303 C CG2 . ILE   D 4 22  ? 143.093 156.147 92.325  1.00 17.16  ? 21  ILE   L CG2 1 
ATOM   4304 C CD1 . ILE   D 4 22  ? 146.063 157.014 92.528  1.00 15.14  ? 21  ILE   L CD1 1 
ATOM   4305 N N   . THR   D 4 23  ? 140.467 157.874 92.514  1.00 14.47  ? 22  THR   L N   1 
ATOM   4306 C CA  . THR   D 4 23  ? 139.242 158.027 93.285  1.00 18.04  ? 22  THR   L CA  1 
ATOM   4307 C C   . THR   D 4 23  ? 138.937 156.723 94.004  1.00 21.24  ? 22  THR   L C   1 
ATOM   4308 O O   . THR   D 4 23  ? 139.137 155.643 93.442  1.00 23.02  ? 22  THR   L O   1 
ATOM   4309 C CB  . THR   D 4 23  ? 138.063 158.419 92.385  1.00 21.89  ? 22  THR   L CB  1 
ATOM   4310 O OG1 . THR   D 4 23  ? 138.450 159.503 91.532  1.00 20.10  ? 22  THR   L OG1 1 
ATOM   4311 C CG2 . THR   D 4 23  ? 136.866 158.844 93.223  1.00 25.97  ? 22  THR   L CG2 1 
ATOM   4312 N N   . CYS   D 4 24  ? 138.458 156.826 95.247  1.00 24.65  ? 23  CYS   L N   1 
ATOM   4313 C CA  . CYS   D 4 24  ? 138.006 155.677 96.035  1.00 26.42  ? 23  CYS   L CA  1 
ATOM   4314 C C   . CYS   D 4 24  ? 136.615 156.024 96.557  1.00 32.19  ? 23  CYS   L C   1 
ATOM   4315 O O   . CYS   D 4 24  ? 136.467 156.578 97.649  1.00 28.76  ? 23  CYS   L O   1 
ATOM   4316 C CB  . CYS   D 4 24  ? 138.985 155.352 97.165  1.00 22.73  ? 23  CYS   L CB  1 
ATOM   4317 S SG  . CYS   D 4 24  ? 138.450 154.028 98.276  1.00 41.82  ? 23  CYS   L SG  1 
ATOM   4318 N N   . ARG   D 4 25  ? 135.596 155.700 95.764  1.00 39.83  ? 24  ARG   L N   1 
ATOM   4319 C CA  . ARG   D 4 25  ? 134.229 156.067 96.107  1.00 44.13  ? 24  ARG   L CA  1 
ATOM   4320 C C   . ARG   D 4 25  ? 133.765 155.328 97.356  1.00 44.86  ? 24  ARG   L C   1 
ATOM   4321 O O   . ARG   D 4 25  ? 134.032 154.137 97.531  1.00 41.69  ? 24  ARG   L O   1 
ATOM   4322 C CB  . ARG   D 4 25  ? 133.292 155.763 94.938  1.00 40.72  ? 24  ARG   L CB  1 
ATOM   4323 N N   . ALA   D 4 26  ? 133.064 156.047 98.227  1.00 48.31  ? 25  ALA   L N   1 
ATOM   4324 C CA  . ALA   D 4 26  ? 132.543 155.466 99.458  1.00 53.05  ? 25  ALA   L CA  1 
ATOM   4325 C C   . ALA   D 4 26  ? 131.287 154.647 99.183  1.00 53.75  ? 25  ALA   L C   1 
ATOM   4326 O O   . ALA   D 4 26  ? 130.218 154.932 99.722  1.00 54.55  ? 25  ALA   L O   1 
ATOM   4327 C CB  . ALA   D 4 26  ? 132.253 156.556 100.478 1.00 50.87  ? 25  ALA   L CB  1 
ATOM   4328 N N   . SER   D 4 31  ? 131.745 156.165 106.524 1.00 42.83  ? 30  SER   L N   1 
ATOM   4329 C CA  . SER   D 4 31  ? 132.297 157.456 106.131 1.00 48.25  ? 30  SER   L CA  1 
ATOM   4330 C C   . SER   D 4 31  ? 133.644 157.703 106.801 1.00 42.24  ? 30  SER   L C   1 
ATOM   4331 O O   . SER   D 4 31  ? 134.057 158.849 106.979 1.00 38.84  ? 30  SER   L O   1 
ATOM   4332 C CB  . SER   D 4 31  ? 131.323 158.585 106.475 1.00 52.06  ? 30  SER   L CB  1 
ATOM   4333 N N   . SER   D 4 32  ? 134.322 156.621 107.174 1.00 33.48  ? 31  SER   L N   1 
ATOM   4334 C CA  . SER   D 4 32  ? 135.622 156.740 107.818 1.00 30.59  ? 31  SER   L CA  1 
ATOM   4335 C C   . SER   D 4 32  ? 136.655 157.283 106.839 1.00 31.91  ? 31  SER   L C   1 
ATOM   4336 O O   . SER   D 4 32  ? 136.527 157.125 105.622 1.00 34.31  ? 31  SER   L O   1 
ATOM   4337 C CB  . SER   D 4 32  ? 136.072 155.384 108.361 1.00 30.50  ? 31  SER   L CB  1 
ATOM   4338 O OG  . SER   D 4 32  ? 135.141 154.877 109.300 1.00 34.91  ? 31  SER   L OG  1 
ATOM   4339 N N   . ALA   D 4 33  ? 137.678 157.941 107.379 1.00 29.44  ? 32  ALA   L N   1 
ATOM   4340 C CA  . ALA   D 4 33  ? 138.760 158.454 106.551 1.00 22.59  ? 32  ALA   L CA  1 
ATOM   4341 C C   . ALA   D 4 33  ? 139.533 157.301 105.924 1.00 21.76  ? 32  ALA   L C   1 
ATOM   4342 O O   . ALA   D 4 33  ? 139.713 156.248 106.542 1.00 20.67  ? 32  ALA   L O   1 
ATOM   4343 C CB  . ALA   D 4 33  ? 139.691 159.333 107.383 1.00 17.89  ? 32  ALA   L CB  1 
ATOM   4344 N N   . VAL   D 4 34  ? 139.984 157.500 104.687 1.00 19.69  ? 33  VAL   L N   1 
ATOM   4345 C CA  . VAL   D 4 34  ? 140.667 156.440 103.958 1.00 15.30  ? 33  VAL   L CA  1 
ATOM   4346 C C   . VAL   D 4 34  ? 142.178 156.623 104.061 1.00 10.63  ? 33  VAL   L C   1 
ATOM   4347 O O   . VAL   D 4 34  ? 142.690 157.718 104.299 1.00 11.36  ? 33  VAL   L O   1 
ATOM   4348 C CB  . VAL   D 4 34  ? 140.210 156.401 102.490 1.00 19.15  ? 33  VAL   L CB  1 
ATOM   4349 C CG1 . VAL   D 4 34  ? 138.699 156.305 102.409 1.00 26.28  ? 33  VAL   L CG1 1 
ATOM   4350 C CG2 . VAL   D 4 34  ? 140.701 157.630 101.751 1.00 15.80  ? 33  VAL   L CG2 1 
ATOM   4351 N N   . ALA   D 4 35  ? 142.898 155.521 103.882 1.00 8.45   ? 34  ALA   L N   1 
ATOM   4352 C CA  . ALA   D 4 35  ? 144.351 155.522 103.823 1.00 6.80   ? 34  ALA   L CA  1 
ATOM   4353 C C   . ALA   D 4 35  ? 144.787 154.943 102.487 1.00 7.80   ? 34  ALA   L C   1 
ATOM   4354 O O   . ALA   D 4 35  ? 144.143 154.031 101.962 1.00 12.44  ? 34  ALA   L O   1 
ATOM   4355 C CB  . ALA   D 4 35  ? 144.958 154.719 104.975 1.00 6.43   ? 34  ALA   L CB  1 
ATOM   4356 N N   . TRP   D 4 36  ? 145.874 155.471 101.935 1.00 5.52   ? 35  TRP   L N   1 
ATOM   4357 C CA  . TRP   D 4 36  ? 146.344 155.088 100.610 1.00 4.98   ? 35  TRP   L CA  1 
ATOM   4358 C C   . TRP   D 4 36  ? 147.714 154.436 100.717 1.00 5.04   ? 35  TRP   L C   1 
ATOM   4359 O O   . TRP   D 4 36  ? 148.619 154.988 101.350 1.00 5.75   ? 35  TRP   L O   1 
ATOM   4360 C CB  . TRP   D 4 36  ? 146.405 156.302 99.685  1.00 6.49   ? 35  TRP   L CB  1 
ATOM   4361 C CG  . TRP   D 4 36  ? 145.058 156.864 99.363  1.00 9.16   ? 35  TRP   L CG  1 
ATOM   4362 C CD1 . TRP   D 4 36  ? 144.359 157.782 100.090 1.00 10.13  ? 35  TRP   L CD1 1 
ATOM   4363 C CD2 . TRP   D 4 36  ? 144.242 156.547 98.230  1.00 9.28   ? 35  TRP   L CD2 1 
ATOM   4364 N NE1 . TRP   D 4 36  ? 143.160 158.056 99.482  1.00 11.08  ? 35  TRP   L NE1 1 
ATOM   4365 C CE2 . TRP   D 4 36  ? 143.064 157.311 98.337  1.00 9.52   ? 35  TRP   L CE2 1 
ATOM   4366 C CE3 . TRP   D 4 36  ? 144.393 155.693 97.135  1.00 9.82   ? 35  TRP   L CE3 1 
ATOM   4367 C CZ2 . TRP   D 4 36  ? 142.046 157.245 97.394  1.00 10.77  ? 35  TRP   L CZ2 1 
ATOM   4368 C CZ3 . TRP   D 4 36  ? 143.382 155.631 96.201  1.00 11.82  ? 35  TRP   L CZ3 1 
ATOM   4369 C CH2 . TRP   D 4 36  ? 142.224 156.402 96.335  1.00 13.08  ? 35  TRP   L CH2 1 
ATOM   4370 N N   . TYR   D 4 37  ? 147.863 153.267 100.095 1.00 5.93   ? 36  TYR   L N   1 
ATOM   4371 C CA  . TYR   D 4 37  ? 149.110 152.519 100.109 1.00 6.35   ? 36  TYR   L CA  1 
ATOM   4372 C C   . TYR   D 4 37  ? 149.629 152.302 98.693  1.00 7.99   ? 36  TYR   L C   1 
ATOM   4373 O O   . TYR   D 4 37  ? 148.877 152.330 97.716  1.00 8.25   ? 36  TYR   L O   1 
ATOM   4374 C CB  . TYR   D 4 37  ? 148.960 151.154 100.797 1.00 5.64   ? 36  TYR   L CB  1 
ATOM   4375 C CG  . TYR   D 4 37  ? 148.449 151.192 102.216 1.00 4.87   ? 36  TYR   L CG  1 
ATOM   4376 C CD1 . TYR   D 4 37  ? 147.128 151.493 102.496 1.00 4.94   ? 36  TYR   L CD1 1 
ATOM   4377 C CD2 . TYR   D 4 37  ? 149.293 150.910 103.278 1.00 6.42   ? 36  TYR   L CD2 1 
ATOM   4378 C CE1 . TYR   D 4 37  ? 146.667 151.522 103.789 1.00 5.18   ? 36  TYR   L CE1 1 
ATOM   4379 C CE2 . TYR   D 4 37  ? 148.841 150.936 104.573 1.00 6.65   ? 36  TYR   L CE2 1 
ATOM   4380 C CZ  . TYR   D 4 37  ? 147.527 151.244 104.824 1.00 6.36   ? 36  TYR   L CZ  1 
ATOM   4381 O OH  . TYR   D 4 37  ? 147.067 151.272 106.117 1.00 9.96   ? 36  TYR   L OH  1 
ATOM   4382 N N   . GLN   D 4 38  ? 150.938 152.077 98.605  1.00 10.32  ? 37  GLN   L N   1 
ATOM   4383 C CA  . GLN   D 4 38  ? 151.624 151.766 97.360  1.00 13.33  ? 37  GLN   L CA  1 
ATOM   4384 C C   . GLN   D 4 38  ? 152.371 150.452 97.515  1.00 18.11  ? 37  GLN   L C   1 
ATOM   4385 O O   . GLN   D 4 38  ? 153.085 150.252 98.501  1.00 19.79  ? 37  GLN   L O   1 
ATOM   4386 C CB  . GLN   D 4 38  ? 152.615 152.869 96.976  1.00 10.84  ? 37  GLN   L CB  1 
ATOM   4387 C CG  . GLN   D 4 38  ? 153.291 152.663 95.634  1.00 16.39  ? 37  GLN   L CG  1 
ATOM   4388 C CD  . GLN   D 4 38  ? 153.008 153.786 94.665  1.00 21.83  ? 37  GLN   L CD  1 
ATOM   4389 O OE1 . GLN   D 4 38  ? 151.944 154.396 94.706  1.00 17.26  ? 37  GLN   L OE1 1 
ATOM   4390 N NE2 . GLN   D 4 38  ? 153.960 154.067 93.786  1.00 27.90  ? 37  GLN   L NE2 1 
ATOM   4391 N N   . GLN   D 4 39  ? 152.215 149.561 96.538  1.00 17.50  ? 38  GLN   L N   1 
ATOM   4392 C CA  . GLN   D 4 39  ? 152.954 148.305 96.553  1.00 23.63  ? 38  GLN   L CA  1 
ATOM   4393 C C   . GLN   D 4 39  ? 153.528 148.033 95.173  1.00 30.92  ? 38  GLN   L C   1 
ATOM   4394 O O   . GLN   D 4 39  ? 152.783 147.937 94.193  1.00 28.55  ? 38  GLN   L O   1 
ATOM   4395 C CB  . GLN   D 4 39  ? 152.067 147.135 96.993  1.00 26.74  ? 38  GLN   L CB  1 
ATOM   4396 C CG  . GLN   D 4 39  ? 152.537 145.784 96.471  1.00 28.74  ? 38  GLN   L CG  1 
ATOM   4397 C CD  . GLN   D 4 39  ? 151.764 144.624 97.057  1.00 23.83  ? 38  GLN   L CD  1 
ATOM   4398 O OE1 . GLN   D 4 39  ? 150.535 144.590 97.003  1.00 22.45  ? 38  GLN   L OE1 1 
ATOM   4399 N NE2 . GLN   D 4 39  ? 152.484 143.659 97.614  1.00 22.88  ? 38  GLN   L NE2 1 
ATOM   4400 N N   . LYS   D 4 40  ? 154.845 147.915 95.106  1.00 37.18  ? 39  LYS   L N   1 
ATOM   4401 C CA  . LYS   D 4 40  ? 155.539 147.463 93.911  1.00 40.20  ? 39  LYS   L CA  1 
ATOM   4402 C C   . LYS   D 4 40  ? 155.422 145.952 93.795  1.00 44.34  ? 39  LYS   L C   1 
ATOM   4403 O O   . LYS   D 4 40  ? 155.250 145.252 94.796  1.00 46.17  ? 39  LYS   L O   1 
ATOM   4404 C CB  . LYS   D 4 40  ? 157.000 147.904 93.972  1.00 43.14  ? 39  LYS   L CB  1 
ATOM   4405 N N   . PRO   D 4 41  ? 155.501 145.405 92.581  1.00 43.62  ? 40  PRO   L N   1 
ATOM   4406 C CA  . PRO   D 4 41  ? 155.330 143.952 92.424  1.00 47.16  ? 40  PRO   L CA  1 
ATOM   4407 C C   . PRO   D 4 41  ? 156.403 143.181 93.178  1.00 53.01  ? 40  PRO   L C   1 
ATOM   4408 O O   . PRO   D 4 41  ? 157.585 143.528 93.144  1.00 55.26  ? 40  PRO   L O   1 
ATOM   4409 C CB  . PRO   D 4 41  ? 155.432 143.748 90.909  1.00 43.56  ? 40  PRO   L CB  1 
ATOM   4410 C CG  . PRO   D 4 41  ? 156.266 144.880 90.436  1.00 46.71  ? 40  PRO   L CG  1 
ATOM   4411 C CD  . PRO   D 4 41  ? 155.916 146.047 91.320  1.00 44.50  ? 40  PRO   L CD  1 
ATOM   4412 N N   . GLY   D 4 42  ? 155.975 142.124 93.864  1.00 54.42  ? 41  GLY   L N   1 
ATOM   4413 C CA  . GLY   D 4 42  ? 156.870 141.319 94.671  1.00 55.99  ? 41  GLY   L CA  1 
ATOM   4414 C C   . GLY   D 4 42  ? 157.476 142.076 95.835  1.00 58.37  ? 41  GLY   L C   1 
ATOM   4415 O O   . GLY   D 4 42  ? 158.647 141.874 96.171  1.00 65.22  ? 41  GLY   L O   1 
ATOM   4416 N N   . LYS   D 4 43  ? 156.689 142.946 96.463  1.00 53.43  ? 42  LYS   L N   1 
ATOM   4417 C CA  . LYS   D 4 43  ? 157.155 143.758 97.581  1.00 49.51  ? 42  LYS   L CA  1 
ATOM   4418 C C   . LYS   D 4 43  ? 156.011 143.909 98.578  1.00 43.33  ? 42  LYS   L C   1 
ATOM   4419 O O   . LYS   D 4 43  ? 154.913 143.380 98.380  1.00 40.61  ? 42  LYS   L O   1 
ATOM   4420 C CB  . LYS   D 4 43  ? 157.670 145.120 97.094  1.00 45.93  ? 42  LYS   L CB  1 
ATOM   4421 C CG  . LYS   D 4 43  ? 159.003 145.068 96.368  1.00 53.94  ? 42  LYS   L CG  1 
ATOM   4422 C CD  . LYS   D 4 43  ? 159.679 146.427 96.353  1.00 61.02  ? 42  LYS   L CD  1 
ATOM   4423 C CE  . LYS   D 4 43  ? 160.858 146.443 95.393  1.00 67.63  ? 42  LYS   L CE  1 
ATOM   4424 N NZ  . LYS   D 4 43  ? 161.661 145.191 95.479  1.00 71.74  ? 42  LYS   L NZ  1 
ATOM   4425 N N   . ALA   D 4 44  ? 156.274 144.643 99.661  1.00 37.44  ? 43  ALA   L N   1 
ATOM   4426 C CA  . ALA   D 4 44  ? 155.268 144.909 100.677 1.00 25.97  ? 43  ALA   L CA  1 
ATOM   4427 C C   . ALA   D 4 44  ? 154.695 146.300 100.469 1.00 24.72  ? 43  ALA   L C   1 
ATOM   4428 O O   . ALA   D 4 44  ? 155.411 147.185 99.974  1.00 30.26  ? 43  ALA   L O   1 
ATOM   4429 C CB  . ALA   D 4 44  ? 155.870 144.790 102.071 1.00 27.65  ? 43  ALA   L CB  1 
ATOM   4430 N N   . PRO   D 4 45  ? 153.430 146.540 100.806 1.00 19.41  ? 44  PRO   L N   1 
ATOM   4431 C CA  . PRO   D 4 45  ? 152.857 147.878 100.624 1.00 16.81  ? 44  PRO   L CA  1 
ATOM   4432 C C   . PRO   D 4 45  ? 153.489 148.903 101.556 1.00 17.72  ? 44  PRO   L C   1 
ATOM   4433 O O   . PRO   D 4 45  ? 153.988 148.572 102.633 1.00 18.79  ? 44  PRO   L O   1 
ATOM   4434 C CB  . PRO   D 4 45  ? 151.372 147.670 100.940 1.00 13.56  ? 44  PRO   L CB  1 
ATOM   4435 C CG  . PRO   D 4 45  ? 151.139 146.219 100.723 1.00 12.40  ? 44  PRO   L CG  1 
ATOM   4436 C CD  . PRO   D 4 45  ? 152.404 145.538 101.131 1.00 18.70  ? 44  PRO   L CD  1 
ATOM   4437 N N   . LYS   D 4 46  ? 153.469 150.160 101.125 1.00 14.71  ? 45  LYS   L N   1 
ATOM   4438 C CA  . LYS   D 4 46  ? 153.933 151.288 101.917 1.00 14.00  ? 45  LYS   L CA  1 
ATOM   4439 C C   . LYS   D 4 46  ? 152.809 152.304 102.067 1.00 10.69  ? 45  LYS   L C   1 
ATOM   4440 O O   . LYS   D 4 46  ? 152.017 152.518 101.148 1.00 9.62   ? 45  LYS   L O   1 
ATOM   4441 C CB  . LYS   D 4 46  ? 155.151 151.953 101.265 1.00 14.21  ? 45  LYS   L CB  1 
ATOM   4442 C CG  . LYS   D 4 46  ? 156.244 150.986 100.837 1.00 17.01  ? 45  LYS   L CG  1 
ATOM   4443 C CD  . LYS   D 4 46  ? 157.294 151.658 99.954  1.00 19.07  ? 45  LYS   L CD  1 
ATOM   4444 C CE  . LYS   D 4 46  ? 157.180 153.178 99.971  1.00 18.16  ? 45  LYS   L CE  1 
ATOM   4445 N NZ  . LYS   D 4 46  ? 158.240 153.829 99.153  1.00 23.21  ? 45  LYS   L NZ  1 
ATOM   4446 N N   . LEU   D 4 47  ? 152.749 152.937 103.236 1.00 8.54   ? 46  LEU   L N   1 
ATOM   4447 C CA  . LEU   D 4 47  ? 151.705 153.912 103.521 1.00 6.76   ? 46  LEU   L CA  1 
ATOM   4448 C C   . LEU   D 4 47  ? 152.110 155.281 102.995 1.00 8.08   ? 46  LEU   L C   1 
ATOM   4449 O O   . LEU   D 4 47  ? 153.248 155.720 103.180 1.00 12.12  ? 46  LEU   L O   1 
ATOM   4450 C CB  . LEU   D 4 47  ? 151.419 153.987 105.023 1.00 6.44   ? 46  LEU   L CB  1 
ATOM   4451 C CG  . LEU   D 4 47  ? 150.342 154.988 105.457 1.00 6.68   ? 46  LEU   L CG  1 
ATOM   4452 C CD1 . LEU   D 4 47  ? 148.957 154.503 105.070 1.00 5.57   ? 46  LEU   L CD1 1 
ATOM   4453 C CD2 . LEU   D 4 47  ? 150.408 155.255 106.951 1.00 8.03   ? 46  LEU   L CD2 1 
ATOM   4454 N N   . LEU   D 4 48  ? 151.171 155.948 102.326 1.00 5.81   ? 47  LEU   L N   1 
ATOM   4455 C CA  . LEU   D 4 48  ? 151.428 157.244 101.708 1.00 6.17   ? 47  LEU   L CA  1 
ATOM   4456 C C   . LEU   D 4 48  ? 150.566 158.346 102.307 1.00 6.34   ? 47  LEU   L C   1 
ATOM   4457 O O   . LEU   D 4 48  ? 151.097 159.382 102.718 1.00 8.11   ? 47  LEU   L O   1 
ATOM   4458 C CB  . LEU   D 4 48  ? 151.196 157.154 100.195 1.00 7.89   ? 47  LEU   L CB  1 
ATOM   4459 C CG  . LEU   D 4 48  ? 151.980 156.104 99.408  1.00 8.48   ? 47  LEU   L CG  1 
ATOM   4460 C CD1 . LEU   D 4 48  ? 151.678 156.238 97.928  1.00 14.19  ? 47  LEU   L CD1 1 
ATOM   4461 C CD2 . LEU   D 4 48  ? 153.470 156.213 99.669  1.00 9.22   ? 47  LEU   L CD2 1 
ATOM   4462 N N   . ILE   D 4 49  ? 149.252 158.158 102.361 1.00 4.75   ? 48  ILE   L N   1 
ATOM   4463 C CA  . ILE   D 4 49  ? 148.312 159.181 102.796 1.00 4.48   ? 48  ILE   L CA  1 
ATOM   4464 C C   . ILE   D 4 49  ? 147.357 158.567 103.806 1.00 5.16   ? 48  ILE   L C   1 
ATOM   4465 O O   . ILE   D 4 49  ? 146.651 157.601 103.503 1.00 7.27   ? 48  ILE   L O   1 
ATOM   4466 C CB  . ILE   D 4 49  ? 147.528 159.768 101.602 1.00 3.99   ? 48  ILE   L CB  1 
ATOM   4467 C CG1 . ILE   D 4 49  ? 148.450 160.578 100.690 1.00 6.35   ? 48  ILE   L CG1 1 
ATOM   4468 C CG2 . ILE   D 4 49  ? 146.349 160.599 102.085 1.00 4.61   ? 48  ILE   L CG2 1 
ATOM   4469 C CD1 . ILE   D 4 49  ? 148.622 162.011 101.107 1.00 11.34  ? 48  ILE   L CD1 1 
ATOM   4470 N N   . TYR   D 4 50  ? 147.324 159.134 105.008 1.00 5.30   ? 49  TYR   L N   1 
ATOM   4471 C CA  . TYR   D 4 50  ? 146.430 158.666 106.056 1.00 5.70   ? 49  TYR   L CA  1 
ATOM   4472 C C   . TYR   D 4 50  ? 145.550 159.812 106.528 1.00 7.74   ? 49  TYR   L C   1 
ATOM   4473 O O   . TYR   D 4 50  ? 145.771 160.971 106.170 1.00 9.64   ? 49  TYR   L O   1 
ATOM   4474 C CB  . TYR   D 4 50  ? 147.208 158.061 107.235 1.00 4.87   ? 49  TYR   L CB  1 
ATOM   4475 C CG  . TYR   D 4 50  ? 147.948 159.065 108.087 1.00 6.05   ? 49  TYR   L CG  1 
ATOM   4476 C CD1 . TYR   D 4 50  ? 149.249 159.432 107.782 1.00 8.80   ? 49  TYR   L CD1 1 
ATOM   4477 C CD2 . TYR   D 4 50  ? 147.355 159.630 109.206 1.00 6.34   ? 49  TYR   L CD2 1 
ATOM   4478 C CE1 . TYR   D 4 50  ? 149.933 160.344 108.560 1.00 11.57  ? 49  TYR   L CE1 1 
ATOM   4479 C CE2 . TYR   D 4 50  ? 148.030 160.544 109.988 1.00 6.71   ? 49  TYR   L CE2 1 
ATOM   4480 C CZ  . TYR   D 4 50  ? 149.319 160.896 109.660 1.00 8.52   ? 49  TYR   L CZ  1 
ATOM   4481 O OH  . TYR   D 4 50  ? 150.000 161.805 110.436 1.00 8.78   ? 49  TYR   L OH  1 
ATOM   4482 N N   . SER   D 4 51  ? 144.532 159.471 107.320 1.00 8.29   ? 50  SER   L N   1 
ATOM   4483 C CA  . SER   D 4 51  ? 143.549 160.418 107.844 1.00 12.42  ? 50  SER   L CA  1 
ATOM   4484 C C   . SER   D 4 51  ? 142.839 161.200 106.746 1.00 11.28  ? 50  SER   L C   1 
ATOM   4485 O O   . SER   D 4 51  ? 142.283 162.271 107.007 1.00 13.27  ? 50  SER   L O   1 
ATOM   4486 C CB  . SER   D 4 51  ? 144.185 161.390 108.843 1.00 13.22  ? 50  SER   L CB  1 
ATOM   4487 O OG  . SER   D 4 51  ? 144.629 160.710 110.001 1.00 11.95  ? 50  SER   L OG  1 
ATOM   4488 N N   . ALA   D 4 52  ? 142.875 160.697 105.516 1.00 8.99   ? 51  ALA   L N   1 
ATOM   4489 C CA  . ALA   D 4 52  ? 142.206 161.184 104.318 1.00 10.84  ? 51  ALA   L CA  1 
ATOM   4490 C C   . ALA   D 4 52  ? 142.819 162.476 103.792 1.00 14.79  ? 51  ALA   L C   1 
ATOM   4491 O O   . ALA   D 4 52  ? 142.468 162.893 102.689 1.00 21.92  ? 51  ALA   L O   1 
ATOM   4492 C CB  . ALA   D 4 52  ? 140.692 161.399 104.511 1.00 13.03  ? 51  ALA   L CB  1 
ATOM   4493 N N   . SER   D 4 53  ? 143.713 163.128 104.530 1.00 12.72  ? 52  SER   L N   1 
ATOM   4494 C CA  . SER   D 4 53  ? 144.438 164.263 103.972 1.00 12.00  ? 52  SER   L CA  1 
ATOM   4495 C C   . SER   D 4 53  ? 145.880 164.370 104.441 1.00 8.52   ? 52  SER   L C   1 
ATOM   4496 O O   . SER   D 4 53  ? 146.561 165.313 104.031 1.00 12.75  ? 52  SER   L O   1 
ATOM   4497 C CB  . SER   D 4 53  ? 143.692 165.568 104.295 1.00 12.98  ? 52  SER   L CB  1 
ATOM   4498 O OG  . SER   D 4 53  ? 144.416 166.694 103.833 1.00 13.98  ? 52  SER   L OG  1 
ATOM   4499 N N   . SER   D 4 54  ? 146.380 163.450 105.259 1.00 6.40   ? 53  SER   L N   1 
ATOM   4500 C CA  . SER   D 4 54  ? 147.655 163.620 105.941 1.00 7.10   ? 53  SER   L CA  1 
ATOM   4501 C C   . SER   D 4 54  ? 148.695 162.686 105.345 1.00 5.77   ? 53  SER   L C   1 
ATOM   4502 O O   . SER   D 4 54  ? 148.430 161.496 105.151 1.00 8.34   ? 53  SER   L O   1 
ATOM   4503 C CB  . SER   D 4 54  ? 147.511 163.363 107.443 1.00 10.05  ? 53  SER   L CB  1 
ATOM   4504 O OG  . SER   D 4 54  ? 146.659 164.321 108.046 1.00 9.29   ? 53  SER   L OG  1 
ATOM   4505 N N   . LEU   D 4 55  ? 149.875 163.229 105.065 1.00 4.89   ? 54  LEU   L N   1 
ATOM   4506 C CA  . LEU   D 4 55  ? 150.943 162.464 104.443 1.00 7.10   ? 54  LEU   L CA  1 
ATOM   4507 C C   . LEU   D 4 55  ? 151.699 161.637 105.473 1.00 6.63   ? 54  LEU   L C   1 
ATOM   4508 O O   . LEU   D 4 55  ? 151.786 162.004 106.647 1.00 6.63   ? 54  LEU   L O   1 
ATOM   4509 C CB  . LEU   D 4 55  ? 151.912 163.400 103.720 1.00 9.53   ? 54  LEU   L CB  1 
ATOM   4510 C CG  . LEU   D 4 55  ? 151.500 163.887 102.331 1.00 11.65  ? 54  LEU   L CG  1 
ATOM   4511 C CD1 . LEU   D 4 55  ? 150.578 165.091 102.426 1.00 8.96   ? 54  LEU   L CD1 1 
ATOM   4512 C CD2 . LEU   D 4 55  ? 152.727 164.213 101.498 1.00 21.02  ? 54  LEU   L CD2 1 
ATOM   4513 N N   . TYR   D 4 56  ? 152.246 160.514 105.021 1.00 7.95   ? 55  TYR   L N   1 
ATOM   4514 C CA  . TYR   D 4 56  ? 153.117 159.702 105.854 1.00 10.25  ? 55  TYR   L CA  1 
ATOM   4515 C C   . TYR   D 4 56  ? 154.489 160.354 105.982 1.00 19.24  ? 55  TYR   L C   1 
ATOM   4516 O O   . TYR   D 4 56  ? 154.867 161.218 105.188 1.00 21.58  ? 55  TYR   L O   1 
ATOM   4517 C CB  . TYR   D 4 56  ? 153.256 158.302 105.260 1.00 11.83  ? 55  TYR   L CB  1 
ATOM   4518 C CG  . TYR   D 4 56  ? 153.932 157.293 106.158 1.00 14.52  ? 55  TYR   L CG  1 
ATOM   4519 C CD1 . TYR   D 4 56  ? 153.453 157.034 107.434 1.00 15.56  ? 55  TYR   L CD1 1 
ATOM   4520 C CD2 . TYR   D 4 56  ? 155.055 156.601 105.727 1.00 15.64  ? 55  TYR   L CD2 1 
ATOM   4521 C CE1 . TYR   D 4 56  ? 154.070 156.111 108.251 1.00 19.08  ? 55  TYR   L CE1 1 
ATOM   4522 C CE2 . TYR   D 4 56  ? 155.679 155.679 106.536 1.00 16.91  ? 55  TYR   L CE2 1 
ATOM   4523 C CZ  . TYR   D 4 56  ? 155.184 155.438 107.797 1.00 20.15  ? 55  TYR   L CZ  1 
ATOM   4524 O OH  . TYR   D 4 56  ? 155.810 154.518 108.606 1.00 28.00  ? 55  TYR   L OH  1 
ATOM   4525 N N   . SER   D 4 57  ? 155.237 159.931 106.999 1.00 27.34  ? 56  SER   L N   1 
ATOM   4526 C CA  . SER   D 4 57  ? 156.580 160.458 107.205 1.00 29.23  ? 56  SER   L CA  1 
ATOM   4527 C C   . SER   D 4 57  ? 157.541 159.902 106.161 1.00 25.32  ? 56  SER   L C   1 
ATOM   4528 O O   . SER   D 4 57  ? 157.567 158.698 105.894 1.00 24.03  ? 56  SER   L O   1 
ATOM   4529 C CB  . SER   D 4 57  ? 157.074 160.114 108.610 1.00 29.00  ? 56  SER   L CB  1 
ATOM   4530 O OG  . SER   D 4 57  ? 157.706 158.847 108.634 1.00 25.54  ? 56  SER   L OG  1 
ATOM   4531 N N   . GLY   D 4 58  ? 158.340 160.790 105.575 1.00 25.62  ? 57  GLY   L N   1 
ATOM   4532 C CA  . GLY   D 4 58  ? 159.287 160.397 104.552 1.00 31.03  ? 57  GLY   L CA  1 
ATOM   4533 C C   . GLY   D 4 58  ? 158.701 160.183 103.177 1.00 35.18  ? 57  GLY   L C   1 
ATOM   4534 O O   . GLY   D 4 58  ? 159.335 159.520 102.348 1.00 38.58  ? 57  GLY   L O   1 
ATOM   4535 N N   . VAL   D 4 59  ? 157.514 160.716 102.905 1.00 34.67  ? 58  VAL   L N   1 
ATOM   4536 C CA  . VAL   D 4 59  ? 156.854 160.544 101.613 1.00 34.75  ? 58  VAL   L CA  1 
ATOM   4537 C C   . VAL   D 4 59  ? 156.993 161.830 100.806 1.00 45.53  ? 58  VAL   L C   1 
ATOM   4538 O O   . VAL   D 4 59  ? 156.812 162.927 101.357 1.00 51.88  ? 58  VAL   L O   1 
ATOM   4539 C CB  . VAL   D 4 59  ? 155.380 160.152 101.797 1.00 24.26  ? 58  VAL   L CB  1 
ATOM   4540 C CG1 . VAL   D 4 59  ? 154.620 160.265 100.486 1.00 26.34  ? 58  VAL   L CG1 1 
ATOM   4541 C CG2 . VAL   D 4 59  ? 155.285 158.743 102.341 1.00 20.21  ? 58  VAL   L CG2 1 
ATOM   4542 N N   . PRO   D 4 60  ? 157.329 161.750 99.519  1.00 43.66  ? 59  PRO   L N   1 
ATOM   4543 C CA  . PRO   D 4 60  ? 157.372 162.959 98.689  1.00 49.23  ? 59  PRO   L CA  1 
ATOM   4544 C C   . PRO   D 4 60  ? 156.018 163.654 98.652  1.00 46.77  ? 59  PRO   L C   1 
ATOM   4545 O O   . PRO   D 4 60  ? 154.966 163.013 98.670  1.00 43.53  ? 59  PRO   L O   1 
ATOM   4546 C CB  . PRO   D 4 60  ? 157.773 162.423 97.311  1.00 46.63  ? 59  PRO   L CB  1 
ATOM   4547 C CG  . PRO   D 4 60  ? 158.530 161.172 97.611  1.00 43.92  ? 59  PRO   L CG  1 
ATOM   4548 C CD  . PRO   D 4 60  ? 157.842 160.570 98.802  1.00 35.73  ? 59  PRO   L CD  1 
ATOM   4549 N N   . SER   D 4 61  ? 156.054 164.986 98.595  1.00 43.95  ? 60  SER   L N   1 
ATOM   4550 C CA  . SER   D 4 61  ? 154.844 165.787 98.738  1.00 44.30  ? 60  SER   L CA  1 
ATOM   4551 C C   . SER   D 4 61  ? 153.964 165.788 97.493  1.00 43.29  ? 60  SER   L C   1 
ATOM   4552 O O   . SER   D 4 61  ? 152.969 166.520 97.469  1.00 38.91  ? 60  SER   L O   1 
ATOM   4553 C CB  . SER   D 4 61  ? 155.213 167.226 99.102  1.00 48.80  ? 60  SER   L CB  1 
ATOM   4554 N N   . ARG   D 4 62  ? 154.301 165.008 96.463  1.00 41.97  ? 61  ARG   L N   1 
ATOM   4555 C CA  . ARG   D 4 62  ? 153.449 164.961 95.278  1.00 40.53  ? 61  ARG   L CA  1 
ATOM   4556 C C   . ARG   D 4 62  ? 152.091 164.345 95.598  1.00 37.75  ? 61  ARG   L C   1 
ATOM   4557 O O   . ARG   D 4 62  ? 151.056 164.820 95.114  1.00 33.85  ? 61  ARG   L O   1 
ATOM   4558 C CB  . ARG   D 4 62  ? 154.140 164.191 94.152  1.00 42.32  ? 61  ARG   L CB  1 
ATOM   4559 C CG  . ARG   D 4 62  ? 154.777 162.881 94.571  1.00 47.28  ? 61  ARG   L CG  1 
ATOM   4560 C CD  . ARG   D 4 62  ? 155.855 162.468 93.585  1.00 47.76  ? 61  ARG   L CD  1 
ATOM   4561 N NE  . ARG   D 4 62  ? 156.865 161.614 94.199  1.00 49.25  ? 61  ARG   L NE  1 
ATOM   4562 C CZ  . ARG   D 4 62  ? 157.954 161.181 93.579  1.00 50.42  ? 61  ARG   L CZ  1 
ATOM   4563 N NH1 . ARG   D 4 62  ? 158.214 161.516 92.327  1.00 54.39  ? 61  ARG   L NH1 1 
ATOM   4564 N NH2 . ARG   D 4 62  ? 158.804 160.396 94.234  1.00 45.14  ? 61  ARG   L NH2 1 
ATOM   4565 N N   . PHE   D 4 63  ? 152.071 163.291 96.410  1.00 35.94  ? 62  PHE   L N   1 
ATOM   4566 C CA  . PHE   D 4 63  ? 150.814 162.656 96.782  1.00 30.08  ? 62  PHE   L CA  1 
ATOM   4567 C C   . PHE   D 4 63  ? 150.010 163.570 97.696  1.00 22.78  ? 62  PHE   L C   1 
ATOM   4568 O O   . PHE   D 4 63  ? 150.534 164.102 98.678  1.00 24.26  ? 62  PHE   L O   1 
ATOM   4569 C CB  . PHE   D 4 63  ? 151.075 161.319 97.472  1.00 28.17  ? 62  PHE   L CB  1 
ATOM   4570 C CG  . PHE   D 4 63  ? 151.971 160.398 96.696  1.00 27.65  ? 62  PHE   L CG  1 
ATOM   4571 C CD1 . PHE   D 4 63  ? 151.483 159.687 95.614  1.00 25.75  ? 62  PHE   L CD1 1 
ATOM   4572 C CD2 . PHE   D 4 63  ? 153.298 160.236 97.053  1.00 30.37  ? 62  PHE   L CD2 1 
ATOM   4573 C CE1 . PHE   D 4 63  ? 152.302 158.839 94.899  1.00 28.76  ? 62  PHE   L CE1 1 
ATOM   4574 C CE2 . PHE   D 4 63  ? 154.123 159.387 96.341  1.00 31.12  ? 62  PHE   L CE2 1 
ATOM   4575 C CZ  . PHE   D 4 63  ? 153.624 158.688 95.263  1.00 29.47  ? 62  PHE   L CZ  1 
ATOM   4576 N N   . SER   D 4 64  ? 148.731 163.747 97.373  1.00 20.12  ? 63  SER   L N   1 
ATOM   4577 C CA  . SER   D 4 64  ? 147.831 164.553 98.182  1.00 17.17  ? 63  SER   L CA  1 
ATOM   4578 C C   . SER   D 4 64  ? 146.443 163.932 98.152  1.00 16.42  ? 63  SER   L C   1 
ATOM   4579 O O   . SER   D 4 64  ? 145.957 163.511 97.100  1.00 20.86  ? 63  SER   L O   1 
ATOM   4580 C CB  . SER   D 4 64  ? 147.770 166.004 97.689  1.00 19.06  ? 63  SER   L CB  1 
ATOM   4581 N N   . GLY   D 4 65  ? 145.808 163.885 99.317  1.00 14.12  ? 64  GLY   L N   1 
ATOM   4582 C CA  . GLY   D 4 65  ? 144.491 163.294 99.427  1.00 13.05  ? 64  GLY   L CA  1 
ATOM   4583 C C   . GLY   D 4 65  ? 143.414 164.300 99.769  1.00 13.46  ? 64  GLY   L C   1 
ATOM   4584 O O   . GLY   D 4 65  ? 143.672 165.284 100.467 1.00 16.60  ? 64  GLY   L O   1 
ATOM   4585 N N   . SER   D 4 66  ? 142.201 164.066 99.279  1.00 13.26  ? 65  SER   L N   1 
ATOM   4586 C CA  . SER   D 4 66  ? 141.064 164.939 99.530  1.00 15.49  ? 65  SER   L CA  1 
ATOM   4587 C C   . SER   D 4 66  ? 139.830 164.087 99.776  1.00 23.22  ? 65  SER   L C   1 
ATOM   4588 O O   . SER   D 4 66  ? 139.801 162.910 99.402  1.00 26.15  ? 65  SER   L O   1 
ATOM   4589 C CB  . SER   D 4 66  ? 140.828 165.893 98.357  1.00 14.41  ? 65  SER   L CB  1 
ATOM   4590 N N   . ARG   D 4 67  ? 138.823 164.677 100.410 1.00 29.60  ? 66  ARG   L N   1 
ATOM   4591 C CA  . ARG   D 4 67  ? 137.569 163.981 100.669 1.00 37.77  ? 66  ARG   L CA  1 
ATOM   4592 C C   . ARG   D 4 67  ? 136.496 164.418 99.679  1.00 38.61  ? 66  ARG   L C   1 
ATOM   4593 O O   . ARG   D 4 67  ? 135.903 165.486 99.826  1.00 40.98  ? 66  ARG   L O   1 
ATOM   4594 C CB  . ARG   D 4 67  ? 137.099 164.233 102.102 1.00 38.83  ? 66  ARG   L CB  1 
ATOM   4595 N N   . GLY   D 4 69  ? 133.867 165.886 98.214  1.00 46.77  ? 68  GLY   L N   1 
ATOM   4596 C CA  . GLY   D 4 69  ? 132.706 165.607 99.037  1.00 47.71  ? 68  GLY   L CA  1 
ATOM   4597 C C   . GLY   D 4 69  ? 132.822 164.304 99.803  1.00 52.49  ? 68  GLY   L C   1 
ATOM   4598 O O   . GLY   D 4 69  ? 133.341 164.273 100.919 1.00 50.87  ? 68  GLY   L O   1 
ATOM   4599 N N   . THR   D 4 70  ? 132.337 163.220 99.198  1.00 55.43  ? 69  THR   L N   1 
ATOM   4600 C CA  . THR   D 4 70  ? 132.393 161.901 99.808  1.00 51.77  ? 69  THR   L CA  1 
ATOM   4601 C C   . THR   D 4 70  ? 133.272 160.919 99.047  1.00 50.69  ? 69  THR   L C   1 
ATOM   4602 O O   . THR   D 4 70  ? 133.668 159.898 99.620  1.00 49.60  ? 69  THR   L O   1 
ATOM   4603 C CB  . THR   D 4 70  ? 130.980 161.311 99.939  1.00 47.19  ? 69  THR   L CB  1 
ATOM   4604 N N   . ASP   D 4 71  ? 133.587 161.194 97.784  1.00 48.68  ? 70  ASP   L N   1 
ATOM   4605 C CA  . ASP   D 4 71  ? 134.450 160.324 96.988  1.00 41.93  ? 70  ASP   L CA  1 
ATOM   4606 C C   . ASP   D 4 71  ? 135.893 160.736 97.244  1.00 39.83  ? 70  ASP   L C   1 
ATOM   4607 O O   . ASP   D 4 71  ? 136.407 161.668 96.620  1.00 38.30  ? 70  ASP   L O   1 
ATOM   4608 C CB  . ASP   D 4 71  ? 134.092 160.413 95.509  1.00 39.54  ? 70  ASP   L CB  1 
ATOM   4609 N N   . PHE   D 4 72  ? 136.546 160.040 98.169  1.00 37.53  ? 71  PHE   L N   1 
ATOM   4610 C CA  . PHE   D 4 72  ? 137.920 160.363 98.526  1.00 30.39  ? 71  PHE   L CA  1 
ATOM   4611 C C   . PHE   D 4 72  ? 138.837 160.141 97.332  1.00 23.15  ? 71  PHE   L C   1 
ATOM   4612 O O   . PHE   D 4 72  ? 138.639 159.216 96.540  1.00 27.79  ? 71  PHE   L O   1 
ATOM   4613 C CB  . PHE   D 4 72  ? 138.370 159.512 99.711  1.00 31.51  ? 71  PHE   L CB  1 
ATOM   4614 C CG  . PHE   D 4 72  ? 137.499 159.658 100.929 1.00 32.67  ? 71  PHE   L CG  1 
ATOM   4615 C CD1 . PHE   D 4 72  ? 136.343 158.909 101.065 1.00 36.98  ? 71  PHE   L CD1 1 
ATOM   4616 C CD2 . PHE   D 4 72  ? 137.837 160.545 101.937 1.00 37.84  ? 71  PHE   L CD2 1 
ATOM   4617 C CE1 . PHE   D 4 72  ? 135.540 159.042 102.181 1.00 47.33  ? 71  PHE   L CE1 1 
ATOM   4618 C CE2 . PHE   D 4 72  ? 137.037 160.683 103.056 1.00 40.86  ? 71  PHE   L CE2 1 
ATOM   4619 C CZ  . PHE   D 4 72  ? 135.888 159.930 103.178 1.00 46.15  ? 71  PHE   L CZ  1 
ATOM   4620 N N   . THR   D 4 73  ? 139.839 161.005 97.194  1.00 16.20  ? 72  THR   L N   1 
ATOM   4621 C CA  . THR   D 4 73  ? 140.687 161.017 96.011  1.00 15.26  ? 72  THR   L CA  1 
ATOM   4622 C C   . THR   D 4 73  ? 142.141 161.205 96.405  1.00 14.36  ? 72  THR   L C   1 
ATOM   4623 O O   . THR   D 4 73  ? 142.463 162.084 97.210  1.00 20.09  ? 72  THR   L O   1 
ATOM   4624 C CB  . THR   D 4 73  ? 140.269 162.127 95.042  1.00 14.17  ? 72  THR   L CB  1 
ATOM   4625 N N   . LEU   D 4 74  ? 143.010 160.381 95.836  1.00 15.05  ? 73  LEU   L N   1 
ATOM   4626 C CA  . LEU   D 4 74  ? 144.445 160.583 95.932  1.00 13.22  ? 73  LEU   L CA  1 
ATOM   4627 C C   . LEU   D 4 74  ? 144.968 161.134 94.615  1.00 15.68  ? 73  LEU   L C   1 
ATOM   4628 O O   . LEU   D 4 74  ? 144.803 160.524 93.555  1.00 18.88  ? 73  LEU   L O   1 
ATOM   4629 C CB  . LEU   D 4 74  ? 145.158 159.274 96.268  1.00 11.63  ? 73  LEU   L CB  1 
ATOM   4630 C CG  . LEU   D 4 74  ? 146.683 159.245 96.149  1.00 9.35   ? 73  LEU   L CG  1 
ATOM   4631 C CD1 . LEU   D 4 74  ? 147.318 160.184 97.153  1.00 15.32  ? 73  LEU   L CD1 1 
ATOM   4632 C CD2 . LEU   D 4 74  ? 147.234 157.835 96.303  1.00 6.77   ? 73  LEU   L CD2 1 
ATOM   4633 N N   . THR   D 4 75  ? 145.625 162.284 94.692  1.00 18.20  ? 74  THR   L N   1 
ATOM   4634 C CA  . THR   D 4 75  ? 146.060 162.974 93.490  1.00 26.23  ? 74  THR   L CA  1 
ATOM   4635 C C   . THR   D 4 75  ? 147.568 163.141 93.557  1.00 25.91  ? 74  THR   L C   1 
ATOM   4636 O O   . THR   D 4 75  ? 148.121 163.395 94.630  1.00 24.46  ? 74  THR   L O   1 
ATOM   4637 C CB  . THR   D 4 75  ? 145.358 164.330 93.355  1.00 26.32  ? 74  THR   L CB  1 
ATOM   4638 O OG1 . THR   D 4 75  ? 143.937 164.130 93.371  1.00 33.35  ? 74  THR   L OG1 1 
ATOM   4639 C CG2 . THR   D 4 75  ? 145.755 165.020 92.044  1.00 24.86  ? 74  THR   L CG2 1 
ATOM   4640 N N   . ILE   D 4 76  ? 148.228 162.971 92.416  1.00 29.66  ? 75  ILE   L N   1 
ATOM   4641 C CA  . ILE   D 4 76  ? 149.678 163.083 92.311  1.00 33.60  ? 75  ILE   L CA  1 
ATOM   4642 C C   . ILE   D 4 76  ? 149.988 164.270 91.413  1.00 46.41  ? 75  ILE   L C   1 
ATOM   4643 O O   . ILE   D 4 76  ? 149.431 164.387 90.315  1.00 50.05  ? 75  ILE   L O   1 
ATOM   4644 C CB  . ILE   D 4 76  ? 150.319 161.799 91.764  1.00 34.04  ? 75  ILE   L CB  1 
ATOM   4645 C CG1 . ILE   D 4 76  ? 149.747 160.575 92.476  1.00 27.88  ? 75  ILE   L CG1 1 
ATOM   4646 C CG2 . ILE   D 4 76  ? 151.826 161.844 91.937  1.00 40.12  ? 75  ILE   L CG2 1 
ATOM   4647 C CD1 . ILE   D 4 76  ? 150.264 159.262 91.942  1.00 25.48  ? 75  ILE   L CD1 1 
ATOM   4648 N N   . SER   D 4 77  ? 150.861 165.160 91.891  1.00 53.15  ? 76  SER   L N   1 
ATOM   4649 C CA  . SER   D 4 77  ? 151.216 166.343 91.116  1.00 55.92  ? 76  SER   L CA  1 
ATOM   4650 C C   . SER   D 4 77  ? 152.005 165.968 89.867  1.00 60.07  ? 76  SER   L C   1 
ATOM   4651 O O   . SER   D 4 77  ? 151.677 166.407 88.759  1.00 54.97  ? 76  SER   L O   1 
ATOM   4652 C CB  . SER   D 4 77  ? 152.008 167.318 91.989  1.00 48.07  ? 76  SER   L CB  1 
ATOM   4653 N N   . SER   D 4 78  ? 153.039 165.144 90.023  1.00 62.17  ? 77  SER   L N   1 
ATOM   4654 C CA  . SER   D 4 78  ? 153.906 164.768 88.912  1.00 58.88  ? 77  SER   L CA  1 
ATOM   4655 C C   . SER   D 4 78  ? 154.384 163.341 89.120  1.00 56.28  ? 77  SER   L C   1 
ATOM   4656 O O   . SER   D 4 78  ? 155.059 163.050 90.112  1.00 56.52  ? 77  SER   L O   1 
ATOM   4657 C CB  . SER   D 4 78  ? 155.099 165.721 88.798  1.00 64.19  ? 77  SER   L CB  1 
ATOM   4658 O OG  . SER   D 4 78  ? 154.831 166.762 87.876  1.00 68.49  ? 77  SER   L OG  1 
ATOM   4659 N N   . LEU   D 4 79  ? 154.039 162.459 88.188  1.00 54.45  ? 78  LEU   L N   1 
ATOM   4660 C CA  . LEU   D 4 79  ? 154.429 161.062 88.280  1.00 52.77  ? 78  LEU   L CA  1 
ATOM   4661 C C   . LEU   D 4 79  ? 155.919 160.898 88.010  1.00 53.00  ? 78  LEU   L C   1 
ATOM   4662 O O   . LEU   D 4 79  ? 156.555 161.737 87.366  1.00 56.81  ? 78  LEU   L O   1 
ATOM   4663 C CB  . LEU   D 4 79  ? 153.623 160.214 87.295  1.00 49.31  ? 78  LEU   L CB  1 
ATOM   4664 C CG  . LEU   D 4 79  ? 152.234 159.784 87.767  1.00 40.81  ? 78  LEU   L CG  1 
ATOM   4665 C CD1 . LEU   D 4 79  ? 151.342 159.433 86.587  1.00 46.81  ? 78  LEU   L CD1 1 
ATOM   4666 C CD2 . LEU   D 4 79  ? 152.344 158.614 88.726  1.00 37.21  ? 78  LEU   L CD2 1 
ATOM   4667 N N   . GLN   D 4 80  ? 156.470 159.805 88.515  1.00 48.99  ? 79  GLN   L N   1 
ATOM   4668 C CA  . GLN   D 4 80  ? 157.872 159.452 88.364  1.00 50.54  ? 79  GLN   L CA  1 
ATOM   4669 C C   . GLN   D 4 80  ? 157.979 157.986 87.985  1.00 53.18  ? 79  GLN   L C   1 
ATOM   4670 O O   . GLN   D 4 80  ? 157.039 157.212 88.196  1.00 54.58  ? 79  GLN   L O   1 
ATOM   4671 C CB  . GLN   D 4 80  ? 158.651 159.718 89.660  1.00 48.05  ? 79  GLN   L CB  1 
ATOM   4672 N N   . PRO   D 4 81  ? 159.108 157.571 87.400  1.00 54.24  ? 80  PRO   L N   1 
ATOM   4673 C CA  . PRO   D 4 81  ? 159.282 156.140 87.101  1.00 55.35  ? 80  PRO   L CA  1 
ATOM   4674 C C   . PRO   D 4 81  ? 159.189 155.256 88.331  1.00 51.25  ? 80  PRO   L C   1 
ATOM   4675 O O   . PRO   D 4 81  ? 158.719 154.116 88.237  1.00 50.34  ? 80  PRO   L O   1 
ATOM   4676 C CB  . PRO   D 4 81  ? 160.677 156.088 86.464  1.00 58.98  ? 80  PRO   L CB  1 
ATOM   4677 C CG  . PRO   D 4 81  ? 160.868 157.447 85.879  1.00 58.28  ? 80  PRO   L CG  1 
ATOM   4678 C CD  . PRO   D 4 81  ? 160.191 158.391 86.830  1.00 55.74  ? 80  PRO   L CD  1 
ATOM   4679 N N   . GLU   D 4 82  ? 159.630 155.751 89.490  1.00 48.17  ? 81  GLU   L N   1 
ATOM   4680 C CA  . GLU   D 4 82  ? 159.525 154.965 90.715  1.00 47.39  ? 81  GLU   L CA  1 
ATOM   4681 C C   . GLU   D 4 82  ? 158.076 154.837 91.167  1.00 44.56  ? 81  GLU   L C   1 
ATOM   4682 O O   . GLU   D 4 82  ? 157.685 153.815 91.741  1.00 49.57  ? 81  GLU   L O   1 
ATOM   4683 C CB  . GLU   D 4 82  ? 160.377 155.594 91.816  1.00 46.00  ? 81  GLU   L CB  1 
ATOM   4684 N N   . ASP   D 4 83  ? 157.263 155.865 90.918  1.00 42.19  ? 82  ASP   L N   1 
ATOM   4685 C CA  . ASP   D 4 83  ? 155.862 155.865 91.337  1.00 43.28  ? 82  ASP   L CA  1 
ATOM   4686 C C   . ASP   D 4 83  ? 155.063 155.249 90.183  1.00 45.12  ? 82  ASP   L C   1 
ATOM   4687 O O   . ASP   D 4 83  ? 154.455 155.927 89.352  1.00 45.10  ? 82  ASP   L O   1 
ATOM   4688 C CB  . ASP   D 4 83  ? 155.437 157.287 91.709  1.00 45.05  ? 82  ASP   L CB  1 
ATOM   4689 C CG  . ASP   D 4 83  ? 153.916 157.529 91.691  1.00 45.45  ? 82  ASP   L CG  1 
ATOM   4690 O OD1 . ASP   D 4 83  ? 153.099 156.643 91.363  1.00 44.12  ? 82  ASP   L OD1 1 
ATOM   4691 O OD2 . ASP   D 4 83  ? 153.531 158.673 92.012  1.00 43.47  ? 82  ASP   L OD2 1 
ATOM   4692 N N   . PHE   D 4 84  ? 155.136 153.919 90.107  1.00 46.02  ? 83  PHE   L N   1 
ATOM   4693 C CA  . PHE   D 4 84  ? 154.392 153.134 89.119  1.00 43.10  ? 83  PHE   L CA  1 
ATOM   4694 C C   . PHE   D 4 84  ? 154.002 151.825 89.801  1.00 40.03  ? 83  PHE   L C   1 
ATOM   4695 O O   . PHE   D 4 84  ? 154.771 150.860 89.773  1.00 46.02  ? 83  PHE   L O   1 
ATOM   4696 C CB  . PHE   D 4 84  ? 155.225 152.885 87.867  1.00 42.68  ? 83  PHE   L CB  1 
ATOM   4697 C CG  . PHE   D 4 84  ? 155.047 153.924 86.796  1.00 44.54  ? 83  PHE   L CG  1 
ATOM   4698 C CD1 . PHE   D 4 84  ? 153.895 154.689 86.736  1.00 46.58  ? 83  PHE   L CD1 1 
ATOM   4699 C CD2 . PHE   D 4 84  ? 156.040 154.144 85.859  1.00 48.70  ? 83  PHE   L CD2 1 
ATOM   4700 C CE1 . PHE   D 4 84  ? 153.734 155.648 85.755  1.00 54.08  ? 83  PHE   L CE1 1 
ATOM   4701 C CE2 . PHE   D 4 84  ? 155.885 155.103 84.877  1.00 53.13  ? 83  PHE   L CE2 1 
ATOM   4702 C CZ  . PHE   D 4 84  ? 154.730 155.855 84.825  1.00 55.99  ? 83  PHE   L CZ  1 
ATOM   4703 N N   . ALA   D 4 85  ? 152.817 151.797 90.399  1.00 31.32  ? 84  ALA   L N   1 
ATOM   4704 C CA  . ALA   D 4 85  ? 152.413 150.676 91.239  1.00 20.97  ? 84  ALA   L CA  1 
ATOM   4705 C C   . ALA   D 4 85  ? 150.909 150.755 91.467  1.00 17.32  ? 84  ALA   L C   1 
ATOM   4706 O O   . ALA   D 4 85  ? 150.197 151.519 90.808  1.00 19.60  ? 84  ALA   L O   1 
ATOM   4707 C CB  . ALA   D 4 85  ? 153.180 150.670 92.562  1.00 18.10  ? 84  ALA   L CB  1 
ATOM   4708 N N   . THR   D 4 86  ? 150.432 149.948 92.407  1.00 15.23  ? 85  THR   L N   1 
ATOM   4709 C CA  . THR   D 4 86  ? 149.015 149.852 92.714  1.00 13.80  ? 85  THR   L CA  1 
ATOM   4710 C C   . THR   D 4 86  ? 148.681 150.653 93.965  1.00 13.53  ? 85  THR   L C   1 
ATOM   4711 O O   . THR   D 4 86  ? 149.426 150.643 94.948  1.00 14.47  ? 85  THR   L O   1 
ATOM   4712 C CB  . THR   D 4 86  ? 148.614 148.392 92.913  1.00 20.18  ? 85  THR   L CB  1 
ATOM   4713 O OG1 . THR   D 4 86  ? 149.685 147.693 93.558  1.00 25.46  ? 85  THR   L OG1 1 
ATOM   4714 C CG2 . THR   D 4 86  ? 148.326 147.733 91.575  1.00 25.76  ? 85  THR   L CG2 1 
ATOM   4715 N N   . TYR   D 4 87  ? 147.546 151.348 93.920  1.00 12.88  ? 86  TYR   L N   1 
ATOM   4716 C CA  . TYR   D 4 87  ? 147.103 152.196 95.016  1.00 10.43  ? 86  TYR   L CA  1 
ATOM   4717 C C   . TYR   D 4 87  ? 145.891 151.574 95.693  1.00 10.39  ? 86  TYR   L C   1 
ATOM   4718 O O   . TYR   D 4 87  ? 144.848 151.365 95.066  1.00 12.07  ? 86  TYR   L O   1 
ATOM   4719 C CB  . TYR   D 4 87  ? 146.747 153.613 94.541  1.00 10.21  ? 86  TYR   L CB  1 
ATOM   4720 C CG  . TYR   D 4 87  ? 147.835 154.289 93.745  1.00 11.57  ? 86  TYR   L CG  1 
ATOM   4721 C CD1 . TYR   D 4 87  ? 148.061 153.955 92.421  1.00 15.00  ? 86  TYR   L CD1 1 
ATOM   4722 C CD2 . TYR   D 4 87  ? 148.652 155.243 94.325  1.00 13.22  ? 86  TYR   L CD2 1 
ATOM   4723 C CE1 . TYR   D 4 87  ? 149.054 154.560 91.694  1.00 16.50  ? 86  TYR   L CE1 1 
ATOM   4724 C CE2 . TYR   D 4 87  ? 149.647 155.856 93.602  1.00 16.05  ? 86  TYR   L CE2 1 
ATOM   4725 C CZ  . TYR   D 4 87  ? 149.848 155.508 92.288  1.00 16.55  ? 86  TYR   L CZ  1 
ATOM   4726 O OH  . TYR   D 4 87  ? 150.844 156.112 91.559  1.00 24.95  ? 86  TYR   L OH  1 
ATOM   4727 N N   . TYR   D 4 88  ? 146.032 151.299 96.985  1.00 8.17   ? 87  TYR   L N   1 
ATOM   4728 C CA  . TYR   D 4 88  ? 144.994 150.638 97.758  1.00 7.08   ? 87  TYR   L CA  1 
ATOM   4729 C C   . TYR   D 4 88  ? 144.433 151.613 98.778  1.00 8.26   ? 87  TYR   L C   1 
ATOM   4730 O O   . TYR   D 4 88  ? 145.168 152.114 99.632  1.00 7.60   ? 87  TYR   L O   1 
ATOM   4731 C CB  . TYR   D 4 88  ? 145.544 149.401 98.475  1.00 5.80   ? 87  TYR   L CB  1 
ATOM   4732 C CG  . TYR   D 4 88  ? 146.072 148.330 97.548  1.00 6.27   ? 87  TYR   L CG  1 
ATOM   4733 C CD1 . TYR   D 4 88  ? 145.211 147.544 96.796  1.00 8.62   ? 87  TYR   L CD1 1 
ATOM   4734 C CD2 . TYR   D 4 88  ? 147.435 148.108 97.428  1.00 6.69   ? 87  TYR   L CD2 1 
ATOM   4735 C CE1 . TYR   D 4 88  ? 145.697 146.569 95.949  1.00 9.32   ? 87  TYR   L CE1 1 
ATOM   4736 C CE2 . TYR   D 4 88  ? 147.929 147.137 96.587  1.00 7.50   ? 87  TYR   L CE2 1 
ATOM   4737 C CZ  . TYR   D 4 88  ? 147.057 146.370 95.850  1.00 9.67   ? 87  TYR   L CZ  1 
ATOM   4738 O OH  . TYR   D 4 88  ? 147.549 145.400 95.010  1.00 14.27  ? 87  TYR   L OH  1 
ATOM   4739 N N   . CYS   D 4 89  ? 143.134 151.882 98.693  1.00 11.27  ? 88  CYS   L N   1 
ATOM   4740 C CA  . CYS   D 4 89  ? 142.456 152.711 99.676  1.00 10.97  ? 88  CYS   L CA  1 
ATOM   4741 C C   . CYS   D 4 89  ? 141.885 151.821 100.770 1.00 11.11  ? 88  CYS   L C   1 
ATOM   4742 O O   . CYS   D 4 89  ? 141.005 150.992 100.519 1.00 15.31  ? 88  CYS   L O   1 
ATOM   4743 C CB  . CYS   D 4 89  ? 141.354 153.568 99.036  1.00 14.60  ? 88  CYS   L CB  1 
ATOM   4744 S SG  . CYS   D 4 89  ? 139.981 152.690 98.254  1.00 38.80  ? 88  CYS   L SG  1 
ATOM   4745 N N   . GLN   D 4 90  ? 142.399 151.992 101.985 1.00 9.78   ? 89  GLN   L N   1 
ATOM   4746 C CA  . GLN   D 4 90  ? 142.070 151.128 103.114 1.00 11.34  ? 89  GLN   L CA  1 
ATOM   4747 C C   . GLN   D 4 90  ? 141.131 151.891 104.036 1.00 15.64  ? 89  GLN   L C   1 
ATOM   4748 O O   . GLN   D 4 90  ? 141.581 152.645 104.904 1.00 19.89  ? 89  GLN   L O   1 
ATOM   4749 C CB  . GLN   D 4 90  ? 143.337 150.684 103.846 1.00 8.06   ? 89  GLN   L CB  1 
ATOM   4750 C CG  . GLN   D 4 90  ? 143.099 149.970 105.158 1.00 9.85   ? 89  GLN   L CG  1 
ATOM   4751 C CD  . GLN   D 4 90  ? 143.581 150.776 106.341 1.00 12.94  ? 89  GLN   L CD  1 
ATOM   4752 O OE1 . GLN   D 4 90  ? 144.462 151.623 106.207 1.00 14.23  ? 89  GLN   L OE1 1 
ATOM   4753 N NE2 . GLN   D 4 90  ? 143.004 150.522 107.507 1.00 15.53  ? 89  GLN   L NE2 1 
ATOM   4754 N N   . GLN   D 4 91  ? 139.831 151.699 103.845 1.00 16.85  ? 90  GLN   L N   1 
ATOM   4755 C CA  . GLN   D 4 91  ? 138.810 152.453 104.557 1.00 17.86  ? 90  GLN   L CA  1 
ATOM   4756 C C   . GLN   D 4 91  ? 138.340 151.662 105.768 1.00 22.52  ? 90  GLN   L C   1 
ATOM   4757 O O   . GLN   D 4 91  ? 138.100 150.454 105.673 1.00 26.07  ? 90  GLN   L O   1 
ATOM   4758 C CB  . GLN   D 4 91  ? 137.634 152.768 103.632 1.00 20.79  ? 90  GLN   L CB  1 
ATOM   4759 C CG  . GLN   D 4 91  ? 136.657 153.790 104.177 1.00 22.55  ? 90  GLN   L CG  1 
ATOM   4760 C CD  . GLN   D 4 91  ? 135.314 153.181 104.519 1.00 29.84  ? 90  GLN   L CD  1 
ATOM   4761 O OE1 . GLN   D 4 91  ? 135.031 152.036 104.168 1.00 26.03  ? 90  GLN   L OE1 1 
ATOM   4762 N NE2 . GLN   D 4 91  ? 134.474 153.948 105.205 1.00 35.73  ? 90  GLN   L NE2 1 
ATOM   4763 N N   . SER   D 4 92  ? 138.223 152.342 106.905 1.00 26.93  ? 91  SER   L N   1 
ATOM   4764 C CA  . SER   D 4 92  ? 137.779 151.697 108.130 1.00 29.04  ? 91  SER   L CA  1 
ATOM   4765 C C   . SER   D 4 92  ? 136.252 151.644 108.177 1.00 31.93  ? 91  SER   L C   1 
ATOM   4766 O O   . SER   D 4 92  ? 135.549 152.253 107.366 1.00 33.28  ? 91  SER   L O   1 
ATOM   4767 C CB  . SER   D 4 92  ? 138.339 152.430 109.347 1.00 24.61  ? 91  SER   L CB  1 
ATOM   4768 N N   . SER   D 4 93  ? 135.736 150.900 109.147 1.00 35.19  ? 92  SER   L N   1 
ATOM   4769 C CA  . SER   D 4 93  ? 134.300 150.761 109.353 1.00 42.77  ? 92  SER   L CA  1 
ATOM   4770 C C   . SER   D 4 93  ? 134.066 150.562 110.847 1.00 52.71  ? 92  SER   L C   1 
ATOM   4771 O O   . SER   D 4 93  ? 134.930 150.884 111.669 1.00 54.91  ? 92  SER   L O   1 
ATOM   4772 C CB  . SER   D 4 93  ? 133.734 149.619 108.492 1.00 40.04  ? 92  SER   L CB  1 
ATOM   4773 N N   . SER   D 4 94  ? 132.885 150.050 111.201 1.00 55.70  ? 93  SER   L N   1 
ATOM   4774 C CA  . SER   D 4 94  ? 132.535 149.863 112.605 1.00 52.00  ? 93  SER   L CA  1 
ATOM   4775 C C   . SER   D 4 94  ? 133.555 148.981 113.321 1.00 48.71  ? 93  SER   L C   1 
ATOM   4776 O O   . SER   D 4 94  ? 134.060 149.336 114.391 1.00 49.87  ? 93  SER   L O   1 
ATOM   4777 C CB  . SER   D 4 94  ? 131.131 149.266 112.715 1.00 49.74  ? 93  SER   L CB  1 
ATOM   4778 N N   . SER   D 4 95  ? 133.873 147.819 112.740 1.00 43.66  ? 94  SER   L N   1 
ATOM   4779 C CA  . SER   D 4 95  ? 134.831 146.925 113.379 1.00 43.18  ? 94  SER   L CA  1 
ATOM   4780 C C   . SER   D 4 95  ? 135.768 146.242 112.386 1.00 39.58  ? 94  SER   L C   1 
ATOM   4781 O O   . SER   D 4 95  ? 136.551 145.373 112.790 1.00 34.79  ? 94  SER   L O   1 
ATOM   4782 C CB  . SER   D 4 95  ? 134.103 145.860 114.205 1.00 39.73  ? 94  SER   L CB  1 
ATOM   4783 N N   . LEU   D 4 96  ? 135.724 146.609 111.107 1.00 40.92  ? 95  LEU   L N   1 
ATOM   4784 C CA  . LEU   D 4 96  ? 136.535 145.931 110.104 1.00 36.75  ? 95  LEU   L CA  1 
ATOM   4785 C C   . LEU   D 4 96  ? 136.922 146.910 109.008 1.00 34.85  ? 95  LEU   L C   1 
ATOM   4786 O O   . LEU   D 4 96  ? 136.057 147.572 108.430 1.00 34.07  ? 95  LEU   L O   1 
ATOM   4787 C CB  . LEU   D 4 96  ? 135.784 144.737 109.505 1.00 32.02  ? 95  LEU   L CB  1 
ATOM   4788 N N   . ILE   D 4 97  ? 138.220 146.988 108.719 1.00 30.53  ? 96  ILE   L N   1 
ATOM   4789 C CA  . ILE   D 4 97  ? 138.728 147.840 107.650 1.00 23.46  ? 96  ILE   L CA  1 
ATOM   4790 C C   . ILE   D 4 97  ? 138.581 147.115 106.318 1.00 21.64  ? 96  ILE   L C   1 
ATOM   4791 O O   . ILE   D 4 97  ? 138.821 145.906 106.224 1.00 24.69  ? 96  ILE   L O   1 
ATOM   4792 C CB  . ILE   D 4 97  ? 140.189 148.249 107.915 1.00 22.59  ? 96  ILE   L CB  1 
ATOM   4793 C CG1 . ILE   D 4 97  ? 141.080 147.014 108.044 1.00 20.60  ? 96  ILE   L CG1 1 
ATOM   4794 C CG2 . ILE   D 4 97  ? 140.280 149.106 109.165 1.00 26.52  ? 96  ILE   L CG2 1 
ATOM   4795 C CD1 . ILE   D 4 97  ? 142.534 147.329 108.297 1.00 19.39  ? 96  ILE   L CD1 1 
ATOM   4796 N N   . THR   D 4 98  ? 138.172 147.844 105.281 1.00 20.18  ? 97  THR   L N   1 
ATOM   4797 C CA  . THR   D 4 98  ? 137.922 147.245 103.978 1.00 18.36  ? 97  THR   L CA  1 
ATOM   4798 C C   . THR   D 4 98  ? 138.857 147.865 102.952 1.00 18.15  ? 97  THR   L C   1 
ATOM   4799 O O   . THR   D 4 98  ? 138.701 149.037 102.598 1.00 17.15  ? 97  THR   L O   1 
ATOM   4800 C CB  . THR   D 4 98  ? 136.465 147.439 103.542 1.00 20.08  ? 97  THR   L CB  1 
ATOM   4801 O OG1 . THR   D 4 98  ? 136.335 148.684 102.844 1.00 22.51  ? 97  THR   L OG1 1 
ATOM   4802 C CG2 . THR   D 4 98  ? 135.538 147.441 104.749 1.00 22.73  ? 97  THR   L CG2 1 
ATOM   4803 N N   . PHE   D 4 99  ? 139.814 147.075 102.477 1.00 16.25  ? 98  PHE   L N   1 
ATOM   4804 C CA  . PHE   D 4 99  ? 140.750 147.531 101.462 1.00 12.84  ? 98  PHE   L CA  1 
ATOM   4805 C C   . PHE   D 4 99  ? 140.052 147.706 100.119 1.00 12.66  ? 98  PHE   L C   1 
ATOM   4806 O O   . PHE   D 4 99  ? 139.088 147.006 99.798  1.00 16.38  ? 98  PHE   L O   1 
ATOM   4807 C CB  . PHE   D 4 99  ? 141.904 146.542 101.319 1.00 12.27  ? 98  PHE   L CB  1 
ATOM   4808 C CG  . PHE   D 4 99  ? 143.029 146.781 102.277 1.00 9.00   ? 98  PHE   L CG  1 
ATOM   4809 C CD1 . PHE   D 4 99  ? 142.975 146.285 103.565 1.00 10.98  ? 98  PHE   L CD1 1 
ATOM   4810 C CD2 . PHE   D 4 99  ? 144.139 147.509 101.891 1.00 8.41   ? 98  PHE   L CD2 1 
ATOM   4811 C CE1 . PHE   D 4 99  ? 144.014 146.506 104.448 1.00 10.12  ? 98  PHE   L CE1 1 
ATOM   4812 C CE2 . PHE   D 4 99  ? 145.178 147.732 102.769 1.00 9.06   ? 98  PHE   L CE2 1 
ATOM   4813 C CZ  . PHE   D 4 99  ? 145.116 147.230 104.049 1.00 7.46   ? 98  PHE   L CZ  1 
ATOM   4814 N N   . GLY   D 4 100 ? 140.547 148.655 99.336  1.00 11.78  ? 99  GLY   L N   1 
ATOM   4815 C CA  . GLY   D 4 100 ? 140.022 148.868 98.006  1.00 14.97  ? 99  GLY   L CA  1 
ATOM   4816 C C   . GLY   D 4 100 ? 140.530 147.835 97.020  1.00 18.95  ? 99  GLY   L C   1 
ATOM   4817 O O   . GLY   D 4 100 ? 141.462 147.072 97.283  1.00 16.57  ? 99  GLY   L O   1 
ATOM   4818 N N   . GLN   D 4 101 ? 139.891 147.814 95.848  1.00 24.88  ? 100 GLN   L N   1 
ATOM   4819 C CA  . GLN   D 4 101 ? 140.277 146.868 94.808  1.00 23.82  ? 100 GLN   L CA  1 
ATOM   4820 C C   . GLN   D 4 101 ? 141.676 147.135 94.269  1.00 19.43  ? 100 GLN   L C   1 
ATOM   4821 O O   . GLN   D 4 101 ? 142.368 146.188 93.882  1.00 19.89  ? 100 GLN   L O   1 
ATOM   4822 C CB  . GLN   D 4 101 ? 139.264 146.901 93.664  1.00 25.24  ? 100 GLN   L CB  1 
ATOM   4823 C CG  . GLN   D 4 101 ? 137.889 147.400 94.069  1.00 32.71  ? 100 GLN   L CG  1 
ATOM   4824 C CD  . GLN   D 4 101 ? 136.906 147.394 92.916  1.00 42.42  ? 100 GLN   L CD  1 
ATOM   4825 O OE1 . GLN   D 4 101 ? 137.299 147.384 91.750  1.00 45.50  ? 100 GLN   L OE1 1 
ATOM   4826 N NE2 . GLN   D 4 101 ? 135.618 147.402 93.237  1.00 42.55  ? 100 GLN   L NE2 1 
ATOM   4827 N N   . GLY   D 4 102 ? 142.107 148.393 94.240  1.00 17.48  ? 101 GLY   L N   1 
ATOM   4828 C CA  . GLY   D 4 102 ? 143.431 148.730 93.759  1.00 15.95  ? 101 GLY   L CA  1 
ATOM   4829 C C   . GLY   D 4 102 ? 143.440 149.255 92.340  1.00 19.04  ? 101 GLY   L C   1 
ATOM   4830 O O   . GLY   D 4 102 ? 142.832 148.660 91.446  1.00 25.76  ? 101 GLY   L O   1 
ATOM   4831 N N   . THR   D 4 103 ? 144.124 150.371 92.123  1.00 18.05  ? 102 THR   L N   1 
ATOM   4832 C CA  . THR   D 4 103 ? 144.273 150.976 90.809  1.00 22.16  ? 102 THR   L CA  1 
ATOM   4833 C C   . THR   D 4 103 ? 145.741 150.951 90.406  1.00 23.21  ? 102 THR   L C   1 
ATOM   4834 O O   . THR   D 4 103 ? 146.637 151.162 91.223  1.00 19.85  ? 102 THR   L O   1 
ATOM   4835 C CB  . THR   D 4 103 ? 143.736 152.414 90.806  1.00 22.32  ? 102 THR   L CB  1 
ATOM   4836 O OG1 . THR   D 4 103 ? 142.395 152.426 91.309  1.00 20.62  ? 102 THR   L OG1 1 
ATOM   4837 C CG2 . THR   D 4 103 ? 143.741 152.990 89.399  1.00 25.64  ? 102 THR   L CG2 1 
ATOM   4838 N N   . LYS   D 4 104 ? 145.984 150.688 89.125  1.00 28.44  ? 103 LYS   L N   1 
ATOM   4839 C CA  . LYS   D 4 104 ? 147.344 150.505 88.625  1.00 33.40  ? 103 LYS   L CA  1 
ATOM   4840 C C   . LYS   D 4 104 ? 147.613 151.547 87.550  1.00 38.72  ? 103 LYS   L C   1 
ATOM   4841 O O   . LYS   D 4 104 ? 146.844 151.669 86.592  1.00 38.96  ? 103 LYS   L O   1 
ATOM   4842 C CB  . LYS   D 4 104 ? 147.543 149.090 88.078  1.00 33.50  ? 103 LYS   L CB  1 
ATOM   4843 C CG  . LYS   D 4 104 ? 148.972 148.774 87.673  1.00 33.14  ? 103 LYS   L CG  1 
ATOM   4844 C CD  . LYS   D 4 104 ? 149.049 147.483 86.881  1.00 32.43  ? 103 LYS   L CD  1 
ATOM   4845 C CE  . LYS   D 4 104 ? 148.255 147.581 85.591  1.00 44.57  ? 103 LYS   L CE  1 
ATOM   4846 N NZ  . LYS   D 4 104 ? 149.031 147.079 84.425  1.00 61.22  ? 103 LYS   L NZ  1 
ATOM   4847 N N   . VAL   D 4 105 ? 148.698 152.306 87.716  1.00 39.32  ? 104 VAL   L N   1 
ATOM   4848 C CA  . VAL   D 4 105 ? 149.113 153.235 86.675  1.00 44.39  ? 104 VAL   L CA  1 
ATOM   4849 C C   . VAL   D 4 105 ? 150.170 152.582 85.790  1.00 51.50  ? 104 VAL   L C   1 
ATOM   4850 O O   . VAL   D 4 105 ? 151.097 151.911 86.259  1.00 49.79  ? 104 VAL   L O   1 
ATOM   4851 C CB  . VAL   D 4 105 ? 149.626 154.549 87.282  1.00 42.68  ? 104 VAL   L CB  1 
ATOM   4852 C CG1 . VAL   D 4 105 ? 149.835 155.589 86.195  1.00 52.88  ? 104 VAL   L CG1 1 
ATOM   4853 C CG2 . VAL   D 4 105 ? 148.644 155.063 88.316  1.00 38.46  ? 104 VAL   L CG2 1 
ATOM   4854 N N   . GLU   D 4 106 ? 150.026 152.789 84.485  1.00 58.09  ? 105 GLU   L N   1 
ATOM   4855 C CA  . GLU   D 4 106 ? 150.889 152.145 83.503  1.00 62.78  ? 105 GLU   L CA  1 
ATOM   4856 C C   . GLU   D 4 106 ? 151.439 153.215 82.570  1.00 66.37  ? 105 GLU   L C   1 
ATOM   4857 O O   . GLU   D 4 106 ? 150.870 154.302 82.433  1.00 66.46  ? 105 GLU   L O   1 
ATOM   4858 C CB  . GLU   D 4 106 ? 150.139 151.063 82.722  1.00 66.04  ? 105 GLU   L CB  1 
ATOM   4859 C CG  . GLU   D 4 106 ? 149.172 151.605 81.683  1.00 66.65  ? 105 GLU   L CG  1 
ATOM   4860 C CD  . GLU   D 4 106 ? 148.801 150.572 80.637  1.00 75.22  ? 105 GLU   L CD  1 
ATOM   4861 O OE1 . GLU   D 4 106 ? 148.803 149.367 80.963  1.00 76.13  ? 105 GLU   L OE1 1 
ATOM   4862 O OE2 . GLU   D 4 106 ? 148.508 150.966 79.488  1.00 77.61  ? 105 GLU   L OE2 1 
ATOM   4863 N N   . ILE   D 4 107 ? 152.556 152.889 81.929  1.00 67.87  ? 106 ILE   L N   1 
ATOM   4864 C CA  . ILE   D 4 107 ? 153.253 153.817 81.047  1.00 68.44  ? 106 ILE   L CA  1 
ATOM   4865 C C   . ILE   D 4 107 ? 152.432 153.993 79.777  1.00 66.77  ? 106 ILE   L C   1 
ATOM   4866 O O   . ILE   D 4 107 ? 152.030 153.010 79.146  1.00 72.88  ? 106 ILE   L O   1 
ATOM   4867 C CB  . ILE   D 4 107 ? 154.666 153.311 80.718  1.00 69.66  ? 106 ILE   L CB  1 
ATOM   4868 C CG1 . ILE   D 4 107 ? 155.507 153.205 81.990  1.00 66.31  ? 106 ILE   L CG1 1 
ATOM   4869 C CG2 . ILE   D 4 107 ? 155.339 154.226 79.707  1.00 66.19  ? 106 ILE   L CG2 1 
ATOM   4870 C CD1 . ILE   D 4 107 ? 156.851 152.545 81.779  1.00 70.27  ? 106 ILE   L CD1 1 
ATOM   4871 N N   . LYS   D 4 108 ? 152.180 155.245 79.404  1.00 61.50  ? 107 LYS   L N   1 
ATOM   4872 C CA  . LYS   D 4 108 ? 151.530 155.521 78.131  1.00 62.71  ? 107 LYS   L CA  1 
ATOM   4873 C C   . LYS   D 4 108 ? 152.466 155.183 76.976  1.00 68.15  ? 107 LYS   L C   1 
ATOM   4874 O O   . LYS   D 4 108 ? 153.679 155.399 77.044  1.00 65.80  ? 107 LYS   L O   1 
ATOM   4875 C CB  . LYS   D 4 108 ? 151.105 156.987 78.051  1.00 58.05  ? 107 LYS   L CB  1 
ATOM   4876 C CG  . LYS   D 4 108 ? 149.697 157.252 78.547  1.00 54.51  ? 107 LYS   L CG  1 
ATOM   4877 C CD  . LYS   D 4 108 ? 148.667 156.613 77.632  1.00 49.66  ? 107 LYS   L CD  1 
ATOM   4878 C CE  . LYS   D 4 108 ? 147.309 157.274 77.785  1.00 43.20  ? 107 LYS   L CE  1 
ATOM   4879 N NZ  . LYS   D 4 108 ? 147.421 158.758 77.830  1.00 39.63  ? 107 LYS   L NZ  1 
ATOM   4880 N N   . ARG   D 4 109 ? 151.888 154.644 75.907  1.00 73.98  ? 108 ARG   L N   1 
ATOM   4881 C CA  . ARG   D 4 109 ? 152.666 154.253 74.740  1.00 76.88  ? 108 ARG   L CA  1 
ATOM   4882 C C   . ARG   D 4 109 ? 151.753 154.237 73.526  1.00 73.77  ? 108 ARG   L C   1 
ATOM   4883 O O   . ARG   D 4 109 ? 150.528 154.173 73.656  1.00 72.57  ? 108 ARG   L O   1 
ATOM   4884 C CB  . ARG   D 4 109 ? 153.319 152.879 74.934  1.00 79.36  ? 108 ARG   L CB  1 
ATOM   4885 N N   . THR   D 4 110 ? 152.367 154.300 72.347  1.00 72.80  ? 109 THR   L N   1 
ATOM   4886 C CA  . THR   D 4 110 ? 151.612 154.245 71.106  1.00 72.24  ? 109 THR   L CA  1 
ATOM   4887 C C   . THR   D 4 110 ? 150.978 152.868 70.929  1.00 71.40  ? 109 THR   L C   1 
ATOM   4888 O O   . THR   D 4 110 ? 151.503 151.847 71.381  1.00 72.58  ? 109 THR   L O   1 
ATOM   4889 C CB  . THR   D 4 110 ? 152.514 154.564 69.914  1.00 77.03  ? 109 THR   L CB  1 
ATOM   4890 N N   . VAL   D 4 111 ? 149.822 152.854 70.264  1.00 71.52  ? 110 VAL   L N   1 
ATOM   4891 C CA  . VAL   D 4 111 ? 149.115 151.605 70.018  1.00 74.67  ? 110 VAL   L CA  1 
ATOM   4892 C C   . VAL   D 4 111 ? 149.960 150.703 69.124  1.00 76.17  ? 110 VAL   L C   1 
ATOM   4893 O O   . VAL   D 4 111 ? 150.501 151.132 68.096  1.00 75.89  ? 110 VAL   L O   1 
ATOM   4894 C CB  . VAL   D 4 111 ? 147.737 151.883 69.390  1.00 73.11  ? 110 VAL   L CB  1 
ATOM   4895 C CG1 . VAL   D 4 111 ? 147.133 150.605 68.829  1.00 76.78  ? 110 VAL   L CG1 1 
ATOM   4896 C CG2 . VAL   D 4 111 ? 146.807 152.514 70.414  1.00 71.46  ? 110 VAL   L CG2 1 
ATOM   4897 N N   . ALA   D 4 112 ? 150.078 149.438 69.521  1.00 78.23  ? 111 ALA   L N   1 
ATOM   4898 C CA  . ALA   D 4 112 ? 150.874 148.470 68.783  1.00 78.20  ? 111 ALA   L CA  1 
ATOM   4899 C C   . ALA   D 4 112 ? 149.975 147.345 68.294  1.00 79.67  ? 111 ALA   L C   1 
ATOM   4900 O O   . ALA   D 4 112 ? 148.976 146.996 68.929  1.00 78.07  ? 111 ALA   L O   1 
ATOM   4901 C CB  . ALA   D 4 112 ? 152.015 147.906 69.639  1.00 79.87  ? 111 ALA   L CB  1 
ATOM   4902 N N   . ALA   D 4 113 ? 150.346 146.777 67.146  1.00 85.64  ? 112 ALA   L N   1 
ATOM   4903 C CA  . ALA   D 4 113 ? 149.600 145.695 66.531  1.00 86.61  ? 112 ALA   L CA  1 
ATOM   4904 C C   . ALA   D 4 113 ? 150.176 144.346 66.943  1.00 89.37  ? 112 ALA   L C   1 
ATOM   4905 O O   . ALA   D 4 113 ? 151.365 144.088 66.722  1.00 88.47  ? 112 ALA   L O   1 
ATOM   4906 C CB  . ALA   D 4 113 ? 149.619 145.807 65.002  1.00 86.58  ? 112 ALA   L CB  1 
ATOM   4907 N N   . PRO   D 4 114 ? 149.369 143.478 67.549  1.00 90.80  ? 113 PRO   L N   1 
ATOM   4908 C CA  . PRO   D 4 114 ? 149.882 142.174 67.979  1.00 86.52  ? 113 PRO   L CA  1 
ATOM   4909 C C   . PRO   D 4 114 ? 150.337 141.322 66.806  1.00 85.50  ? 113 PRO   L C   1 
ATOM   4910 O O   . PRO   D 4 114 ? 149.759 141.354 65.717  1.00 86.63  ? 113 PRO   L O   1 
ATOM   4911 C CB  . PRO   D 4 114 ? 148.682 141.538 68.693  1.00 80.30  ? 113 PRO   L CB  1 
ATOM   4912 C CG  . PRO   D 4 114 ? 147.490 142.238 68.133  1.00 85.27  ? 113 PRO   L CG  1 
ATOM   4913 C CD  . PRO   D 4 114 ? 147.936 143.639 67.844  1.00 89.19  ? 113 PRO   L CD  1 
ATOM   4914 N N   . SER   D 4 115 ? 151.395 140.553 67.045  1.00 86.67  ? 114 SER   L N   1 
ATOM   4915 C CA  . SER   D 4 115 ? 151.901 139.585 66.083  1.00 89.41  ? 114 SER   L CA  1 
ATOM   4916 C C   . SER   D 4 115 ? 151.449 138.198 66.521  1.00 83.66  ? 114 SER   L C   1 
ATOM   4917 O O   . SER   D 4 115 ? 151.940 137.670 67.524  1.00 79.16  ? 114 SER   L O   1 
ATOM   4918 C CB  . SER   D 4 115 ? 153.425 139.653 65.983  1.00 91.20  ? 114 SER   L CB  1 
ATOM   4919 N N   . VAL   D 4 116 ? 150.522 137.614 65.770  1.00 84.21  ? 115 VAL   L N   1 
ATOM   4920 C CA  . VAL   D 4 116 ? 149.874 136.364 66.147  1.00 87.12  ? 115 VAL   L CA  1 
ATOM   4921 C C   . VAL   D 4 116 ? 150.615 135.205 65.502  1.00 89.23  ? 115 VAL   L C   1 
ATOM   4922 O O   . VAL   D 4 116 ? 150.748 135.146 64.273  1.00 93.13  ? 115 VAL   L O   1 
ATOM   4923 C CB  . VAL   D 4 116 ? 148.391 136.362 65.739  1.00 90.27  ? 115 VAL   L CB  1 
ATOM   4924 C CG1 . VAL   D 4 116 ? 147.696 135.125 66.282  1.00 91.94  ? 115 VAL   L CG1 1 
ATOM   4925 C CG2 . VAL   D 4 116 ? 147.707 137.628 66.230  1.00 80.84  ? 115 VAL   L CG2 1 
ATOM   4926 N N   . PHE   D 4 117 ? 151.099 134.283 66.330  1.00 85.47  ? 116 PHE   L N   1 
ATOM   4927 C CA  . PHE   D 4 117 ? 151.721 133.051 65.866  1.00 90.72  ? 116 PHE   L CA  1 
ATOM   4928 C C   . PHE   D 4 117 ? 151.045 131.880 66.560  1.00 89.00  ? 116 PHE   L C   1 
ATOM   4929 O O   . PHE   D 4 117 ? 150.996 131.833 67.793  1.00 85.48  ? 116 PHE   L O   1 
ATOM   4930 C CB  . PHE   D 4 117 ? 153.227 133.045 66.148  1.00 91.24  ? 116 PHE   L CB  1 
ATOM   4931 C CG  . PHE   D 4 117 ? 153.995 134.065 65.359  1.00 91.08  ? 116 PHE   L CG  1 
ATOM   4932 C CD1 . PHE   D 4 117 ? 154.389 133.801 64.058  1.00 92.29  ? 116 PHE   L CD1 1 
ATOM   4933 C CD2 . PHE   D 4 117 ? 154.322 135.289 65.917  1.00 84.83  ? 116 PHE   L CD2 1 
ATOM   4934 C CE1 . PHE   D 4 117 ? 155.096 134.738 63.329  1.00 90.01  ? 116 PHE   L CE1 1 
ATOM   4935 C CE2 . PHE   D 4 117 ? 155.028 136.230 65.194  1.00 89.30  ? 116 PHE   L CE2 1 
ATOM   4936 C CZ  . PHE   D 4 117 ? 155.415 135.955 63.898  1.00 94.80  ? 116 PHE   L CZ  1 
ATOM   4937 N N   . ILE   D 4 118 ? 150.529 130.941 65.774  1.00 95.49  ? 117 ILE   L N   1 
ATOM   4938 C CA  . ILE   D 4 118 ? 149.834 129.769 66.292  1.00 96.05  ? 117 ILE   L CA  1 
ATOM   4939 C C   . ILE   D 4 118 ? 150.766 128.572 66.175  1.00 95.96  ? 117 ILE   L C   1 
ATOM   4940 O O   . ILE   D 4 118 ? 151.407 128.370 65.135  1.00 103.41 ? 117 ILE   L O   1 
ATOM   4941 C CB  . ILE   D 4 118 ? 148.496 129.534 65.566  1.00 96.33  ? 117 ILE   L CB  1 
ATOM   4942 C CG1 . ILE   D 4 118 ? 147.696 128.430 66.261  1.00 93.73  ? 117 ILE   L CG1 1 
ATOM   4943 C CG2 . ILE   D 4 118 ? 148.705 129.227 64.086  1.00 99.69  ? 117 ILE   L CG2 1 
ATOM   4944 C CD1 . ILE   D 4 118 ? 146.249 128.370 65.833  1.00 99.57  ? 117 ILE   L CD1 1 
ATOM   4945 N N   . PHE   D 4 119 ? 150.876 127.803 67.257  1.00 91.42  ? 118 PHE   L N   1 
ATOM   4946 C CA  . PHE   D 4 119 ? 151.836 126.713 67.339  1.00 96.20  ? 118 PHE   L CA  1 
ATOM   4947 C C   . PHE   D 4 119 ? 151.113 125.377 67.335  1.00 101.06 ? 118 PHE   L C   1 
ATOM   4948 O O   . PHE   D 4 119 ? 150.345 125.094 68.267  1.00 103.75 ? 118 PHE   L O   1 
ATOM   4949 C CB  . PHE   D 4 119 ? 152.695 126.850 68.596  1.00 92.73  ? 118 PHE   L CB  1 
ATOM   4950 C CG  . PHE   D 4 119 ? 153.508 128.115 68.644  1.00 93.86  ? 118 PHE   L CG  1 
ATOM   4951 C CD1 . PHE   D 4 119 ? 153.819 128.804 67.482  1.00 95.81  ? 118 PHE   L CD1 1 
ATOM   4952 C CD2 . PHE   D 4 119 ? 153.955 128.619 69.853  1.00 92.22  ? 118 PHE   L CD2 1 
ATOM   4953 C CE1 . PHE   D 4 119 ? 154.564 129.967 67.526  1.00 94.71  ? 118 PHE   L CE1 1 
ATOM   4954 C CE2 . PHE   D 4 119 ? 154.701 129.782 69.903  1.00 90.58  ? 118 PHE   L CE2 1 
ATOM   4955 C CZ  . PHE   D 4 119 ? 155.005 130.456 68.738  1.00 92.36  ? 118 PHE   L CZ  1 
ATOM   4956 N N   . PRO   D 4 120 ? 151.313 124.538 66.324  1.00 96.29  ? 119 PRO   L N   1 
ATOM   4957 C CA  . PRO   D 4 120 ? 150.716 123.199 66.335  1.00 97.24  ? 119 PRO   L CA  1 
ATOM   4958 C C   . PRO   D 4 120 ? 151.328 122.344 67.430  1.00 102.53 ? 119 PRO   L C   1 
ATOM   4959 O O   . PRO   D 4 120 ? 152.483 122.565 67.826  1.00 103.09 ? 119 PRO   L O   1 
ATOM   4960 C CB  . PRO   D 4 120 ? 151.056 122.650 64.941  1.00 100.46 ? 119 PRO   L CB  1 
ATOM   4961 C CG  . PRO   D 4 120 ? 152.271 123.410 64.527  1.00 97.18  ? 119 PRO   L CG  1 
ATOM   4962 C CD  . PRO   D 4 120 ? 152.104 124.784 65.106  1.00 92.33  ? 119 PRO   L CD  1 
ATOM   4963 N N   . PRO   D 4 121 ? 150.583 121.372 67.955  1.00 106.29 ? 120 PRO   L N   1 
ATOM   4964 C CA  . PRO   D 4 121 ? 151.133 120.508 69.007  1.00 107.29 ? 120 PRO   L CA  1 
ATOM   4965 C C   . PRO   D 4 121 ? 152.364 119.754 68.526  1.00 109.78 ? 120 PRO   L C   1 
ATOM   4966 O O   . PRO   D 4 121 ? 152.448 119.330 67.372  1.00 107.68 ? 120 PRO   L O   1 
ATOM   4967 C CB  . PRO   D 4 121 ? 149.976 119.553 69.320  1.00 106.55 ? 120 PRO   L CB  1 
ATOM   4968 C CG  . PRO   D 4 121 ? 148.753 120.312 68.925  1.00 105.95 ? 120 PRO   L CG  1 
ATOM   4969 C CD  . PRO   D 4 121 ? 149.155 121.105 67.714  1.00 106.83 ? 120 PRO   L CD  1 
ATOM   4970 N N   . SER   D 4 122 ? 153.325 119.590 69.431  1.00 113.12 ? 121 SER   L N   1 
ATOM   4971 C CA  . SER   D 4 122 ? 154.575 118.931 69.087  1.00 113.85 ? 121 SER   L CA  1 
ATOM   4972 C C   . SER   D 4 122 ? 154.387 117.422 68.975  1.00 116.12 ? 121 SER   L C   1 
ATOM   4973 O O   . SER   D 4 122 ? 153.474 116.837 69.567  1.00 116.83 ? 121 SER   L O   1 
ATOM   4974 C CB  . SER   D 4 122 ? 155.648 119.245 70.128  1.00 114.98 ? 121 SER   L CB  1 
ATOM   4975 O OG  . SER   D 4 122 ? 155.259 118.792 71.412  1.00 112.85 ? 121 SER   L OG  1 
ATOM   4976 N N   . ASP   D 4 123 ? 155.273 116.791 68.200  1.00 118.78 ? 122 ASP   L N   1 
ATOM   4977 C CA  . ASP   D 4 123 ? 155.224 115.341 68.044  1.00 117.81 ? 122 ASP   L CA  1 
ATOM   4978 C C   . ASP   D 4 123 ? 155.482 114.635 69.369  1.00 120.62 ? 122 ASP   L C   1 
ATOM   4979 O O   . ASP   D 4 123 ? 154.864 113.605 69.662  1.00 123.68 ? 122 ASP   L O   1 
ATOM   4980 C CB  . ASP   D 4 123 ? 156.236 114.893 66.990  1.00 116.13 ? 122 ASP   L CB  1 
ATOM   4981 N N   . SER   D 4 124 ? 156.396 115.172 70.181  1.00 118.78 ? 123 SER   L N   1 
ATOM   4982 C CA  . SER   D 4 124 ? 156.667 114.573 71.485  1.00 118.42 ? 123 SER   L CA  1 
ATOM   4983 C C   . SER   D 4 124 ? 155.434 114.616 72.380  1.00 119.72 ? 123 SER   L C   1 
ATOM   4984 O O   . SER   D 4 124 ? 155.099 113.624 73.039  1.00 118.68 ? 123 SER   L O   1 
ATOM   4985 C CB  . SER   D 4 124 ? 157.842 115.285 72.154  1.00 115.96 ? 123 SER   L CB  1 
ATOM   4986 N N   . GLN   D 4 125 ? 154.736 115.753 72.406  1.00 117.13 ? 124 GLN   L N   1 
ATOM   4987 C CA  . GLN   D 4 125 ? 153.539 115.859 73.234  1.00 115.49 ? 124 GLN   L CA  1 
ATOM   4988 C C   . GLN   D 4 125 ? 152.419 114.976 72.696  1.00 119.69 ? 124 GLN   L C   1 
ATOM   4989 O O   . GLN   D 4 125 ? 151.649 114.397 73.472  1.00 118.90 ? 124 GLN   L O   1 
ATOM   4990 C CB  . GLN   D 4 125 ? 153.087 117.315 73.322  1.00 109.08 ? 124 GLN   L CB  1 
ATOM   4991 C CG  . GLN   D 4 125 ? 152.257 117.626 74.554  1.00 107.68 ? 124 GLN   L CG  1 
ATOM   4992 C CD  . GLN   D 4 125 ? 151.531 118.949 74.448  1.00 104.80 ? 124 GLN   L CD  1 
ATOM   4993 O OE1 . GLN   D 4 125 ? 151.582 119.616 73.415  1.00 101.05 ? 124 GLN   L OE1 1 
ATOM   4994 N NE2 . GLN   D 4 125 ? 150.849 119.337 75.518  1.00 103.88 ? 124 GLN   L NE2 1 
ATOM   4995 N N   . LEU   D 4 126 ? 152.307 114.865 71.369  1.00 122.42 ? 125 LEU   L N   1 
ATOM   4996 C CA  . LEU   D 4 126 ? 151.313 113.967 70.788  1.00 123.75 ? 125 LEU   L CA  1 
ATOM   4997 C C   . LEU   D 4 126 ? 151.596 112.517 71.160  1.00 126.56 ? 125 LEU   L C   1 
ATOM   4998 O O   . LEU   D 4 126 ? 150.671 111.756 71.469  1.00 128.00 ? 125 LEU   L O   1 
ATOM   4999 C CB  . LEU   D 4 126 ? 151.276 114.134 69.269  1.00 119.63 ? 125 LEU   L CB  1 
ATOM   5000 C CG  . LEU   D 4 126 ? 150.563 115.380 68.743  1.00 117.25 ? 125 LEU   L CG  1 
ATOM   5001 C CD1 . LEU   D 4 126 ? 150.470 115.340 67.226  1.00 117.00 ? 125 LEU   L CD1 1 
ATOM   5002 C CD2 . LEU   D 4 126 ? 149.181 115.504 69.365  1.00 118.00 ? 125 LEU   L CD2 1 
ATOM   5003 N N   . LYS   D 4 127 ? 152.869 112.115 71.130  1.00 125.67 ? 126 LYS   L N   1 
ATOM   5004 C CA  . LYS   D 4 127 ? 153.230 110.767 71.557  1.00 125.67 ? 126 LYS   L CA  1 
ATOM   5005 C C   . LYS   D 4 127 ? 152.945 110.569 73.040  1.00 128.39 ? 126 LYS   L C   1 
ATOM   5006 O O   . LYS   D 4 127 ? 152.533 109.482 73.462  1.00 130.93 ? 126 LYS   L O   1 
ATOM   5007 C CB  . LYS   D 4 127 ? 154.703 110.495 71.250  1.00 124.20 ? 126 LYS   L CB  1 
ATOM   5008 N N   . SER   D 4 128 ? 153.168 111.609 73.847  1.00 127.04 ? 127 SER   L N   1 
ATOM   5009 C CA  . SER   D 4 128 ? 152.830 111.533 75.264  1.00 128.49 ? 127 SER   L CA  1 
ATOM   5010 C C   . SER   D 4 128 ? 151.334 111.340 75.472  1.00 128.17 ? 127 SER   L C   1 
ATOM   5011 O O   . SER   D 4 128 ? 150.923 110.580 76.357  1.00 128.20 ? 127 SER   L O   1 
ATOM   5012 C CB  . SER   D 4 128 ? 153.310 112.792 75.987  1.00 124.75 ? 127 SER   L CB  1 
ATOM   5013 N N   . GLY   D 4 129 ? 150.507 112.013 74.676  1.00 124.91 ? 128 GLY   L N   1 
ATOM   5014 C CA  . GLY   D 4 129 ? 149.064 111.855 74.747  1.00 124.43 ? 128 GLY   L CA  1 
ATOM   5015 C C   . GLY   D 4 129 ? 148.281 113.136 74.952  1.00 120.93 ? 128 GLY   L C   1 
ATOM   5016 O O   . GLY   D 4 129 ? 147.056 113.065 75.130  1.00 121.16 ? 128 GLY   L O   1 
ATOM   5017 N N   . THR   D 4 130 ? 148.913 114.304 74.940  1.00 117.93 ? 129 THR   L N   1 
ATOM   5018 C CA  . THR   D 4 130 ? 148.230 115.574 75.139  1.00 116.36 ? 129 THR   L CA  1 
ATOM   5019 C C   . THR   D 4 130 ? 148.485 116.485 73.946  1.00 117.43 ? 129 THR   L C   1 
ATOM   5020 O O   . THR   D 4 130 ? 149.566 116.455 73.350  1.00 118.65 ? 129 THR   L O   1 
ATOM   5021 C CB  . THR   D 4 130 ? 148.701 116.251 76.431  1.00 117.70 ? 129 THR   L CB  1 
ATOM   5022 O OG1 . THR   D 4 130 ? 148.654 115.307 77.508  1.00 122.33 ? 129 THR   L OG1 1 
ATOM   5023 C CG2 . THR   D 4 130 ? 147.809 117.432 76.776  1.00 112.48 ? 129 THR   L CG2 1 
ATOM   5024 N N   . ALA   D 4 131 ? 147.481 117.284 73.592  1.00 117.20 ? 130 ALA   L N   1 
ATOM   5025 C CA  . ALA   D 4 131 ? 147.580 118.241 72.498  1.00 114.43 ? 130 ALA   L CA  1 
ATOM   5026 C C   . ALA   D 4 131 ? 147.504 119.652 73.060  1.00 107.36 ? 130 ALA   L C   1 
ATOM   5027 O O   . ALA   D 4 131 ? 146.593 119.968 73.832  1.00 100.80 ? 130 ALA   L O   1 
ATOM   5028 C CB  . ALA   D 4 131 ? 146.471 118.019 71.468  1.00 113.02 ? 130 ALA   L CB  1 
ATOM   5029 N N   . SER   D 4 132 ? 148.459 120.495 72.674  1.00 108.92 ? 131 SER   L N   1 
ATOM   5030 C CA  . SER   D 4 132 ? 148.510 121.878 73.128  1.00 105.90 ? 131 SER   L CA  1 
ATOM   5031 C C   . SER   D 4 132 ? 148.691 122.801 71.932  1.00 104.77 ? 131 SER   L C   1 
ATOM   5032 O O   . SER   D 4 132 ? 149.617 122.617 71.136  1.00 105.28 ? 131 SER   L O   1 
ATOM   5033 C CB  . SER   D 4 132 ? 149.643 122.091 74.136  1.00 102.71 ? 131 SER   L CB  1 
ATOM   5034 O OG  . SER   D 4 132 ? 149.405 121.358 75.325  1.00 105.58 ? 131 SER   L OG  1 
ATOM   5035 N N   . VAL   D 4 133 ? 147.808 123.789 71.813  1.00 97.26  ? 132 VAL   L N   1 
ATOM   5036 C CA  . VAL   D 4 133 ? 147.877 124.802 70.766  1.00 93.85  ? 132 VAL   L CA  1 
ATOM   5037 C C   . VAL   D 4 133 ? 148.069 126.152 71.442  1.00 91.91  ? 132 VAL   L C   1 
ATOM   5038 O O   . VAL   D 4 133 ? 147.302 126.519 72.341  1.00 87.26  ? 132 VAL   L O   1 
ATOM   5039 C CB  . VAL   D 4 133 ? 146.619 124.797 69.885  1.00 90.79  ? 132 VAL   L CB  1 
ATOM   5040 C CG1 . VAL   D 4 133 ? 146.721 125.868 68.810  1.00 93.75  ? 132 VAL   L CG1 1 
ATOM   5041 C CG2 . VAL   D 4 133 ? 146.417 123.428 69.258  1.00 92.84  ? 132 VAL   L CG2 1 
ATOM   5042 N N   . VAL   D 4 134 ? 149.089 126.890 71.012  1.00 93.25  ? 133 VAL   L N   1 
ATOM   5043 C CA  . VAL   D 4 134 ? 149.462 128.162 71.618  1.00 86.84  ? 133 VAL   L CA  1 
ATOM   5044 C C   . VAL   D 4 134 ? 149.195 129.277 70.618  1.00 86.00  ? 133 VAL   L C   1 
ATOM   5045 O O   . VAL   D 4 134 ? 149.731 129.262 69.504  1.00 90.38  ? 133 VAL   L O   1 
ATOM   5046 C CB  . VAL   D 4 134 ? 150.937 128.165 72.057  1.00 86.14  ? 133 VAL   L CB  1 
ATOM   5047 C CG1 . VAL   D 4 134 ? 151.250 129.415 72.860  1.00 88.00  ? 133 VAL   L CG1 1 
ATOM   5048 C CG2 . VAL   D 4 134 ? 151.257 126.915 72.860  1.00 84.10  ? 133 VAL   L CG2 1 
ATOM   5049 N N   . CYS   D 4 135 ? 148.369 130.242 71.017  1.00 80.46  ? 134 CYS   L N   1 
ATOM   5050 C CA  . CYS   D 4 135 ? 148.136 131.461 70.253  1.00 83.35  ? 134 CYS   L CA  1 
ATOM   5051 C C   . CYS   D 4 135 ? 148.856 132.599 70.962  1.00 78.92  ? 134 CYS   L C   1 
ATOM   5052 O O   . CYS   D 4 135 ? 148.445 133.014 72.051  1.00 75.97  ? 134 CYS   L O   1 
ATOM   5053 C CB  . CYS   D 4 135 ? 146.641 131.758 70.122  1.00 84.80  ? 134 CYS   L CB  1 
ATOM   5054 S SG  . CYS   D 4 135 ? 146.215 132.932 68.812  1.00 82.88  ? 134 CYS   L SG  1 
ATOM   5055 N N   . LEU   D 4 136 ? 149.920 133.102 70.346  1.00 80.94  ? 135 LEU   L N   1 
ATOM   5056 C CA  . LEU   D 4 136 ? 150.841 134.028 70.992  1.00 73.54  ? 135 LEU   L CA  1 
ATOM   5057 C C   . LEU   D 4 136 ? 150.679 135.418 70.393  1.00 75.23  ? 135 LEU   L C   1 
ATOM   5058 O O   . LEU   D 4 136 ? 150.781 135.589 69.174  1.00 84.04  ? 135 LEU   L O   1 
ATOM   5059 C CB  . LEU   D 4 136 ? 152.284 133.548 70.841  1.00 70.79  ? 135 LEU   L CB  1 
ATOM   5060 C CG  . LEU   D 4 136 ? 153.370 134.492 71.354  1.00 69.13  ? 135 LEU   L CG  1 
ATOM   5061 C CD1 . LEU   D 4 136 ? 153.281 134.631 72.865  1.00 72.12  ? 135 LEU   L CD1 1 
ATOM   5062 C CD2 . LEU   D 4 136 ? 154.748 134.005 70.935  1.00 77.13  ? 135 LEU   L CD2 1 
ATOM   5063 N N   . LEU   D 4 137 ? 150.430 136.401 71.253  1.00 66.64  ? 136 LEU   L N   1 
ATOM   5064 C CA  . LEU   D 4 137 ? 150.408 137.811 70.883  1.00 67.44  ? 136 LEU   L CA  1 
ATOM   5065 C C   . LEU   D 4 137 ? 151.665 138.459 71.444  1.00 73.90  ? 136 LEU   L C   1 
ATOM   5066 O O   . LEU   D 4 137 ? 151.898 138.417 72.657  1.00 75.90  ? 136 LEU   L O   1 
ATOM   5067 C CB  . LEU   D 4 137 ? 149.156 138.507 71.417  1.00 63.60  ? 136 LEU   L CB  1 
ATOM   5068 C CG  . LEU   D 4 137 ? 147.789 137.864 71.169  1.00 61.18  ? 136 LEU   L CG  1 
ATOM   5069 C CD1 . LEU   D 4 137 ? 147.433 136.866 72.252  1.00 59.42  ? 136 LEU   L CD1 1 
ATOM   5070 C CD2 . LEU   D 4 137 ? 146.728 138.940 71.088  1.00 69.17  ? 136 LEU   L CD2 1 
ATOM   5071 N N   . ASN   D 4 138 ? 152.471 139.053 70.570  1.00 79.17  ? 137 ASN   L N   1 
ATOM   5072 C CA  . ASN   D 4 138 ? 153.780 139.567 70.943  1.00 81.11  ? 137 ASN   L CA  1 
ATOM   5073 C C   . ASN   D 4 138 ? 153.889 141.045 70.597  1.00 85.57  ? 137 ASN   L C   1 
ATOM   5074 O O   . ASN   D 4 138 ? 153.564 141.456 69.478  1.00 87.39  ? 137 ASN   L O   1 
ATOM   5075 C CB  . ASN   D 4 138 ? 154.894 138.781 70.241  1.00 82.64  ? 137 ASN   L CB  1 
ATOM   5076 C CG  . ASN   D 4 138 ? 156.182 138.755 71.038  1.00 87.74  ? 137 ASN   L CG  1 
ATOM   5077 O OD1 . ASN   D 4 138 ? 156.167 138.840 72.266  1.00 87.64  ? 137 ASN   L OD1 1 
ATOM   5078 N ND2 . ASN   D 4 138 ? 157.306 138.634 70.343  1.00 93.63  ? 137 ASN   L ND2 1 
ATOM   5079 N N   . ASN   D 4 139 ? 154.348 141.835 71.567  1.00 84.96  ? 138 ASN   L N   1 
ATOM   5080 C CA  . ASN   D 4 139 ? 154.642 143.255 71.381  1.00 84.16  ? 138 ASN   L CA  1 
ATOM   5081 C C   . ASN   D 4 139 ? 153.407 144.024 70.909  1.00 82.70  ? 138 ASN   L C   1 
ATOM   5082 O O   . ASN   D 4 139 ? 153.359 144.566 69.804  1.00 85.81  ? 138 ASN   L O   1 
ATOM   5083 C CB  . ASN   D 4 139 ? 155.811 143.442 70.410  1.00 89.34  ? 138 ASN   L CB  1 
ATOM   5084 C CG  . ASN   D 4 139 ? 157.073 142.746 70.877  1.00 86.95  ? 138 ASN   L CG  1 
ATOM   5085 O OD1 . ASN   D 4 139 ? 157.199 142.384 72.047  1.00 83.62  ? 138 ASN   L OD1 1 
ATOM   5086 N ND2 . ASN   D 4 139 ? 158.017 142.554 69.963  1.00 86.24  ? 138 ASN   L ND2 1 
ATOM   5087 N N   . PHE   D 4 140 ? 152.396 144.061 71.773  1.00 79.58  ? 139 PHE   L N   1 
ATOM   5088 C CA  . PHE   D 4 140 ? 151.151 144.762 71.489  1.00 81.72  ? 139 PHE   L CA  1 
ATOM   5089 C C   . PHE   D 4 140 ? 150.766 145.655 72.662  1.00 80.83  ? 139 PHE   L C   1 
ATOM   5090 O O   . PHE   D 4 140 ? 151.070 145.341 73.817  1.00 82.59  ? 139 PHE   L O   1 
ATOM   5091 C CB  . PHE   D 4 140 ? 150.029 143.772 71.162  1.00 83.64  ? 139 PHE   L CB  1 
ATOM   5092 C CG  . PHE   D 4 140 ? 149.164 143.406 72.334  1.00 85.89  ? 139 PHE   L CG  1 
ATOM   5093 C CD1 . PHE   D 4 140 ? 149.668 142.656 73.384  1.00 83.51  ? 139 PHE   L CD1 1 
ATOM   5094 C CD2 . PHE   D 4 140 ? 147.840 143.803 72.380  1.00 87.78  ? 139 PHE   L CD2 1 
ATOM   5095 C CE1 . PHE   D 4 140 ? 148.869 142.314 74.457  1.00 74.44  ? 139 PHE   L CE1 1 
ATOM   5096 C CE2 . PHE   D 4 140 ? 147.039 143.465 73.450  1.00 79.37  ? 139 PHE   L CE2 1 
ATOM   5097 C CZ  . PHE   D 4 140 ? 147.554 142.720 74.490  1.00 70.94  ? 139 PHE   L CZ  1 
ATOM   5098 N N   . TYR   D 4 141 ? 150.114 146.776 72.352  1.00 80.34  ? 140 TYR   L N   1 
ATOM   5099 C CA  . TYR   D 4 141 ? 149.677 147.752 73.338  1.00 78.68  ? 140 TYR   L CA  1 
ATOM   5100 C C   . TYR   D 4 141 ? 148.310 148.275 72.908  1.00 78.63  ? 140 TYR   L C   1 
ATOM   5101 O O   . TYR   D 4 141 ? 148.061 148.422 71.699  1.00 82.23  ? 140 TYR   L O   1 
ATOM   5102 C CB  . TYR   D 4 141 ? 150.693 148.900 73.447  1.00 78.74  ? 140 TYR   L CB  1 
ATOM   5103 C CG  . TYR   D 4 141 ? 150.535 149.766 74.675  1.00 77.88  ? 140 TYR   L CG  1 
ATOM   5104 C CD1 . TYR   D 4 141 ? 151.110 149.399 75.883  1.00 77.96  ? 140 TYR   L CD1 1 
ATOM   5105 C CD2 . TYR   D 4 141 ? 149.816 150.952 74.625  1.00 80.74  ? 140 TYR   L CD2 1 
ATOM   5106 C CE1 . TYR   D 4 141 ? 150.969 150.186 77.008  1.00 77.43  ? 140 TYR   L CE1 1 
ATOM   5107 C CE2 . TYR   D 4 141 ? 149.668 151.744 75.746  1.00 77.17  ? 140 TYR   L CE2 1 
ATOM   5108 C CZ  . TYR   D 4 141 ? 150.247 151.356 76.934  1.00 75.51  ? 140 TYR   L CZ  1 
ATOM   5109 O OH  . TYR   D 4 141 ? 150.104 152.143 78.053  1.00 77.90  ? 140 TYR   L OH  1 
ATOM   5110 N N   . PRO   D 4 142 ? 147.399 148.570 73.846  1.00 77.17  ? 141 PRO   L N   1 
ATOM   5111 C CA  . PRO   D 4 142 ? 147.518 148.465 75.306  1.00 78.45  ? 141 PRO   L CA  1 
ATOM   5112 C C   . PRO   D 4 142 ? 147.299 147.048 75.828  1.00 82.38  ? 141 PRO   L C   1 
ATOM   5113 O O   . PRO   D 4 142 ? 147.372 146.082 75.077  1.00 84.30  ? 141 PRO   L O   1 
ATOM   5114 C CB  . PRO   D 4 142 ? 146.436 149.432 75.796  1.00 73.65  ? 141 PRO   L CB  1 
ATOM   5115 C CG  . PRO   D 4 142 ? 145.358 149.323 74.758  1.00 70.67  ? 141 PRO   L CG  1 
ATOM   5116 C CD  . PRO   D 4 142 ? 146.072 149.075 73.446  1.00 75.26  ? 141 PRO   L CD  1 
ATOM   5117 N N   . ARG   D 4 143 ? 147.039 146.908 77.130  1.00 75.28  ? 142 ARG   L N   1 
ATOM   5118 C CA  . ARG   D 4 143 ? 146.883 145.584 77.723  1.00 63.20  ? 142 ARG   L CA  1 
ATOM   5119 C C   . ARG   D 4 143 ? 145.650 144.866 77.190  1.00 67.97  ? 142 ARG   L C   1 
ATOM   5120 O O   . ARG   D 4 143 ? 145.692 143.655 76.941  1.00 74.61  ? 142 ARG   L O   1 
ATOM   5121 C CB  . ARG   D 4 143 ? 146.819 145.696 79.246  1.00 64.16  ? 142 ARG   L CB  1 
ATOM   5122 C CG  . ARG   D 4 143 ? 146.403 144.410 79.939  1.00 65.80  ? 142 ARG   L CG  1 
ATOM   5123 C CD  . ARG   D 4 143 ? 146.452 144.544 81.448  1.00 63.55  ? 142 ARG   L CD  1 
ATOM   5124 N NE  . ARG   D 4 143 ? 147.801 144.335 81.960  1.00 62.90  ? 142 ARG   L NE  1 
ATOM   5125 C CZ  . ARG   D 4 143 ? 148.155 143.322 82.738  1.00 56.55  ? 142 ARG   L CZ  1 
ATOM   5126 N NH1 . ARG   D 4 143 ? 147.281 142.406 83.121  1.00 62.57  ? 142 ARG   L NH1 1 
ATOM   5127 N NH2 . ARG   D 4 143 ? 149.419 143.225 83.141  1.00 51.50  ? 142 ARG   L NH2 1 
ATOM   5128 N N   . GLU   D 4 144 ? 144.545 145.589 77.012  1.00 70.46  ? 143 GLU   L N   1 
ATOM   5129 C CA  . GLU   D 4 144 ? 143.281 144.956 76.656  1.00 74.84  ? 143 GLU   L CA  1 
ATOM   5130 C C   . GLU   D 4 144 ? 143.387 144.223 75.324  1.00 80.01  ? 143 GLU   L C   1 
ATOM   5131 O O   . GLU   D 4 144 ? 143.931 144.750 74.349  1.00 86.26  ? 143 GLU   L O   1 
ATOM   5132 C CB  . GLU   D 4 144 ? 142.168 146.001 76.593  1.00 76.02  ? 143 GLU   L CB  1 
ATOM   5133 C CG  . GLU   D 4 144 ? 141.799 146.594 77.939  1.00 82.00  ? 143 GLU   L CG  1 
ATOM   5134 C CD  . GLU   D 4 144 ? 142.207 148.048 78.064  1.00 87.94  ? 143 GLU   L CD  1 
ATOM   5135 O OE1 . GLU   D 4 144 ? 143.148 148.466 77.357  1.00 81.21  ? 143 GLU   L OE1 1 
ATOM   5136 O OE2 . GLU   D 4 144 ? 141.586 148.774 78.868  1.00 95.09  ? 143 GLU   L OE2 1 
ATOM   5137 N N   . ALA   D 4 145 ? 142.862 143.001 75.292  1.00 75.12  ? 144 ALA   L N   1 
ATOM   5138 C CA  . ALA   D 4 145 ? 142.842 142.190 74.084  1.00 73.34  ? 144 ALA   L CA  1 
ATOM   5139 C C   . ALA   D 4 145 ? 141.754 141.139 74.227  1.00 78.15  ? 144 ALA   L C   1 
ATOM   5140 O O   . ALA   D 4 145 ? 141.253 140.882 75.325  1.00 82.02  ? 144 ALA   L O   1 
ATOM   5141 C CB  . ALA   D 4 145 ? 144.198 141.529 73.822  1.00 68.05  ? 144 ALA   L CB  1 
ATOM   5142 N N   . LYS   D 4 146 ? 141.392 140.536 73.098  1.00 84.28  ? 145 LYS   L N   1 
ATOM   5143 C CA  . LYS   D 4 146 ? 140.389 139.481 73.061  1.00 87.81  ? 145 LYS   L CA  1 
ATOM   5144 C C   . LYS   D 4 146 ? 140.883 138.366 72.151  1.00 92.53  ? 145 LYS   L C   1 
ATOM   5145 O O   . LYS   D 4 146 ? 141.259 138.620 71.002  1.00 94.95  ? 145 LYS   L O   1 
ATOM   5146 C CB  . LYS   D 4 146 ? 139.041 140.019 72.572  1.00 95.02  ? 145 LYS   L CB  1 
ATOM   5147 C CG  . LYS   D 4 146 ? 138.036 138.947 72.194  1.00 101.14 ? 145 LYS   L CG  1 
ATOM   5148 C CD  . LYS   D 4 146 ? 136.663 139.550 71.954  1.00 113.67 ? 145 LYS   L CD  1 
ATOM   5149 C CE  . LYS   D 4 146 ? 135.579 138.488 71.997  1.00 130.83 ? 145 LYS   L CE  1 
ATOM   5150 N NZ  . LYS   D 4 146 ? 135.419 137.922 73.365  1.00 129.71 ? 145 LYS   L NZ  1 
ATOM   5151 N N   . VAL   D 4 147 ? 140.882 137.139 72.665  1.00 89.42  ? 146 VAL   L N   1 
ATOM   5152 C CA  . VAL   D 4 147 ? 141.349 135.969 71.932  1.00 86.23  ? 146 VAL   L CA  1 
ATOM   5153 C C   . VAL   D 4 147 ? 140.219 134.952 71.884  1.00 88.70  ? 146 VAL   L C   1 
ATOM   5154 O O   . VAL   D 4 147 ? 139.618 134.635 72.918  1.00 87.98  ? 146 VAL   L O   1 
ATOM   5155 C CB  . VAL   D 4 147 ? 142.608 135.359 72.575  1.00 75.35  ? 146 VAL   L CB  1 
ATOM   5156 C CG1 . VAL   D 4 147 ? 143.083 134.158 71.774  1.00 78.21  ? 146 VAL   L CG1 1 
ATOM   5157 C CG2 . VAL   D 4 147 ? 143.707 136.404 72.682  1.00 76.94  ? 146 VAL   L CG2 1 
ATOM   5158 N N   . GLN   D 4 148 ? 139.928 134.448 70.687  1.00 91.71  ? 147 GLN   L N   1 
ATOM   5159 C CA  . GLN   D 4 148 ? 138.860 133.482 70.476  1.00 92.03  ? 147 GLN   L CA  1 
ATOM   5160 C C   . GLN   D 4 148 ? 139.394 132.288 69.700  1.00 95.37  ? 147 GLN   L C   1 
ATOM   5161 O O   . GLN   D 4 148 ? 140.254 132.438 68.827  1.00 97.49  ? 147 GLN   L O   1 
ATOM   5162 C CB  . GLN   D 4 148 ? 137.681 134.112 69.723  1.00 95.13  ? 147 GLN   L CB  1 
ATOM   5163 N N   . TRP   D 4 149 ? 138.882 131.104 70.025  1.00 96.88  ? 148 TRP   L N   1 
ATOM   5164 C CA  . TRP   D 4 149 ? 139.275 129.865 69.366  1.00 100.07 ? 148 TRP   L CA  1 
ATOM   5165 C C   . TRP   D 4 149 ? 138.131 129.358 68.498  1.00 106.11 ? 148 TRP   L C   1 
ATOM   5166 O O   . TRP   D 4 149 ? 136.996 129.230 68.970  1.00 107.84 ? 148 TRP   L O   1 
ATOM   5167 C CB  . TRP   D 4 149 ? 139.677 128.802 70.388  1.00 94.92  ? 148 TRP   L CB  1 
ATOM   5168 C CG  . TRP   D 4 149 ? 140.812 129.207 71.266  1.00 87.39  ? 148 TRP   L CG  1 
ATOM   5169 C CD1 . TRP   D 4 149 ? 140.736 129.850 72.466  1.00 84.22  ? 148 TRP   L CD1 1 
ATOM   5170 C CD2 . TRP   D 4 149 ? 142.203 128.980 71.019  1.00 83.04  ? 148 TRP   L CD2 1 
ATOM   5171 N NE1 . TRP   D 4 149 ? 141.996 130.045 72.978  1.00 78.20  ? 148 TRP   L NE1 1 
ATOM   5172 C CE2 . TRP   D 4 149 ? 142.914 129.519 72.107  1.00 77.04  ? 148 TRP   L CE2 1 
ATOM   5173 C CE3 . TRP   D 4 149 ? 142.917 128.377 69.979  1.00 86.89  ? 148 TRP   L CE3 1 
ATOM   5174 C CZ2 . TRP   D 4 149 ? 144.303 129.472 72.187  1.00 73.05  ? 148 TRP   L CZ2 1 
ATOM   5175 C CZ3 . TRP   D 4 149 ? 144.297 128.331 70.061  1.00 86.36  ? 148 TRP   L CZ3 1 
ATOM   5176 C CH2 . TRP   D 4 149 ? 144.974 128.874 71.157  1.00 77.45  ? 148 TRP   L CH2 1 
ATOM   5177 N N   . LYS   D 4 150 ? 138.433 129.072 67.234  1.00 110.63 ? 149 LYS   L N   1 
ATOM   5178 C CA  . LYS   D 4 150 ? 137.490 128.457 66.309  1.00 119.24 ? 149 LYS   L CA  1 
ATOM   5179 C C   . LYS   D 4 150 ? 138.101 127.163 65.794  1.00 122.42 ? 149 LYS   L C   1 
ATOM   5180 O O   . LYS   D 4 150 ? 139.178 127.181 65.187  1.00 120.90 ? 149 LYS   L O   1 
ATOM   5181 C CB  . LYS   D 4 150 ? 137.157 129.400 65.151  1.00 118.01 ? 149 LYS   L CB  1 
ATOM   5182 N N   . VAL   D 4 151 ? 137.419 126.048 66.036  1.00 126.85 ? 150 VAL   L N   1 
ATOM   5183 C CA  . VAL   D 4 151 ? 137.870 124.730 65.602  1.00 128.73 ? 150 VAL   L CA  1 
ATOM   5184 C C   . VAL   D 4 151 ? 136.853 124.197 64.603  1.00 131.24 ? 150 VAL   L C   1 
ATOM   5185 O O   . VAL   D 4 151 ? 135.671 124.040 64.937  1.00 131.97 ? 150 VAL   L O   1 
ATOM   5186 C CB  . VAL   D 4 151 ? 138.038 123.768 66.787  1.00 124.81 ? 150 VAL   L CB  1 
ATOM   5187 C CG1 . VAL   D 4 151 ? 138.376 122.370 66.292  1.00 122.95 ? 150 VAL   L CG1 1 
ATOM   5188 C CG2 . VAL   D 4 151 ? 139.111 124.279 67.735  1.00 122.82 ? 150 VAL   L CG2 1 
ATOM   5189 N N   . ASP   D 4 152 ? 137.316 123.909 63.385  1.00 131.33 ? 151 ASP   L N   1 
ATOM   5190 C CA  . ASP   D 4 152 ? 136.447 123.471 62.291  1.00 131.61 ? 151 ASP   L CA  1 
ATOM   5191 C C   . ASP   D 4 152 ? 135.294 124.451 62.082  1.00 134.41 ? 151 ASP   L C   1 
ATOM   5192 O O   . ASP   D 4 152 ? 134.138 124.054 61.920  1.00 135.85 ? 151 ASP   L O   1 
ATOM   5193 C CB  . ASP   D 4 152 ? 135.924 122.053 62.531  1.00 131.96 ? 151 ASP   L CB  1 
ATOM   5194 C CG  . ASP   D 4 152 ? 135.684 121.295 61.240  1.00 132.19 ? 151 ASP   L CG  1 
ATOM   5195 O OD1 . ASP   D 4 152 ? 136.044 121.819 60.165  1.00 130.01 ? 151 ASP   L OD1 1 
ATOM   5196 O OD2 . ASP   D 4 152 ? 135.135 120.174 61.300  1.00 135.10 ? 151 ASP   L OD2 1 
ATOM   5197 N N   . ASN   D 4 153 ? 135.619 125.747 62.099  1.00 133.72 ? 152 ASN   L N   1 
ATOM   5198 C CA  . ASN   D 4 153 ? 134.640 126.827 61.954  1.00 134.93 ? 152 ASN   L CA  1 
ATOM   5199 C C   . ASN   D 4 153 ? 133.587 126.793 63.059  1.00 134.49 ? 152 ASN   L C   1 
ATOM   5200 O O   . ASN   D 4 153 ? 132.437 127.186 62.848  1.00 136.46 ? 152 ASN   L O   1 
ATOM   5201 C CB  . ASN   D 4 153 ? 133.972 126.797 60.576  1.00 137.47 ? 152 ASN   L CB  1 
ATOM   5202 N N   . ALA   D 4 154 ? 133.972 126.326 64.246  1.00 131.82 ? 153 ALA   L N   1 
ATOM   5203 C CA  . ALA   D 4 154 ? 133.085 126.284 65.403  1.00 131.51 ? 153 ALA   L CA  1 
ATOM   5204 C C   . ALA   D 4 154 ? 133.826 126.853 66.602  1.00 130.14 ? 153 ALA   L C   1 
ATOM   5205 O O   . ALA   D 4 154 ? 134.963 126.457 66.877  1.00 129.26 ? 153 ALA   L O   1 
ATOM   5206 C CB  . ALA   D 4 154 ? 132.610 124.856 65.688  1.00 128.92 ? 153 ALA   L CB  1 
ATOM   5207 N N   . LEU   D 4 155 ? 133.182 127.774 67.314  1.00 131.19 ? 154 LEU   L N   1 
ATOM   5208 C CA  . LEU   D 4 155 ? 133.819 128.424 68.451  1.00 127.01 ? 154 LEU   L CA  1 
ATOM   5209 C C   . LEU   D 4 155 ? 133.930 127.469 69.633  1.00 124.07 ? 154 LEU   L C   1 
ATOM   5210 O O   . LEU   D 4 155 ? 133.025 126.672 69.899  1.00 124.99 ? 154 LEU   L O   1 
ATOM   5211 C CB  . LEU   D 4 155 ? 133.033 129.671 68.857  1.00 124.84 ? 154 LEU   L CB  1 
ATOM   5212 N N   . GLN   D 4 156 ? 135.050 127.553 70.344  1.00 120.46 ? 155 GLN   L N   1 
ATOM   5213 C CA  . GLN   D 4 156 ? 135.299 126.756 71.535  1.00 121.21 ? 155 GLN   L CA  1 
ATOM   5214 C C   . GLN   D 4 156 ? 135.534 127.662 72.736  1.00 120.45 ? 155 GLN   L C   1 
ATOM   5215 O O   . GLN   D 4 156 ? 136.068 128.768 72.616  1.00 117.76 ? 155 GLN   L O   1 
ATOM   5216 C CB  . GLN   D 4 156 ? 136.503 125.828 71.336  1.00 122.46 ? 155 GLN   L CB  1 
ATOM   5217 C CG  . GLN   D 4 156 ? 136.314 124.784 70.248  1.00 126.20 ? 155 GLN   L CG  1 
ATOM   5218 C CD  . GLN   D 4 156 ? 136.760 123.403 70.686  1.00 127.79 ? 155 GLN   L CD  1 
ATOM   5219 O OE1 . GLN   D 4 156 ? 136.906 123.135 71.878  1.00 127.20 ? 155 GLN   L OE1 1 
ATOM   5220 N NE2 . GLN   D 4 156 ? 136.975 122.516 69.721  1.00 124.25 ? 155 GLN   L NE2 1 
ATOM   5221 N N   . SER   D 4 157 ? 135.124 127.177 73.906  1.00 116.42 ? 156 SER   L N   1 
ATOM   5222 C CA  . SER   D 4 157 ? 135.278 127.917 75.149  1.00 112.96 ? 156 SER   L CA  1 
ATOM   5223 C C   . SER   D 4 157 ? 135.486 126.942 76.298  1.00 109.13 ? 156 SER   L C   1 
ATOM   5224 O O   . SER   D 4 157 ? 135.120 125.767 76.210  1.00 104.16 ? 156 SER   L O   1 
ATOM   5225 C CB  . SER   D 4 157 ? 134.060 128.808 75.430  1.00 108.98 ? 156 SER   L CB  1 
ATOM   5226 N N   . GLY   D 4 158 ? 136.083 127.444 77.377  1.00 109.70 ? 157 GLY   L N   1 
ATOM   5227 C CA  . GLY   D 4 158 ? 136.312 126.649 78.564  1.00 104.61 ? 157 GLY   L CA  1 
ATOM   5228 C C   . GLY   D 4 158 ? 137.509 125.727 78.509  1.00 101.88 ? 157 GLY   L C   1 
ATOM   5229 O O   . GLY   D 4 158 ? 137.666 124.893 79.410  1.00 101.59 ? 157 GLY   L O   1 
ATOM   5230 N N   . ASN   D 4 159 ? 138.358 125.842 77.487  1.00 99.40  ? 158 ASN   L N   1 
ATOM   5231 C CA  . ASN   D 4 159 ? 139.518 124.972 77.332  1.00 94.65  ? 158 ASN   L CA  1 
ATOM   5232 C C   . ASN   D 4 159 ? 140.794 125.753 77.031  1.00 86.40  ? 158 ASN   L C   1 
ATOM   5233 O O   . ASN   D 4 159 ? 141.664 125.255 76.309  1.00 84.45  ? 158 ASN   L O   1 
ATOM   5234 C CB  . ASN   D 4 159 ? 139.261 123.933 76.239  1.00 98.90  ? 158 ASN   L CB  1 
ATOM   5235 C CG  . ASN   D 4 159 ? 138.772 124.556 74.945  1.00 101.89 ? 158 ASN   L CG  1 
ATOM   5236 O OD1 . ASN   D 4 159 ? 138.629 125.774 74.843  1.00 99.09  ? 158 ASN   L OD1 1 
ATOM   5237 N ND2 . ASN   D 4 159 ? 138.513 123.719 73.946  1.00 105.95 ? 158 ASN   L ND2 1 
ATOM   5238 N N   . SER   D 4 160 ? 140.927 126.965 77.565  1.00 83.08  ? 159 SER   L N   1 
ATOM   5239 C CA  . SER   D 4 160 ? 142.093 127.795 77.313  1.00 79.20  ? 159 SER   L CA  1 
ATOM   5240 C C   . SER   D 4 160 ? 142.488 128.548 78.576  1.00 76.95  ? 159 SER   L C   1 
ATOM   5241 O O   . SER   D 4 160 ? 141.670 128.788 79.468  1.00 76.22  ? 159 SER   L O   1 
ATOM   5242 C CB  . SER   D 4 160 ? 141.839 128.789 76.171  1.00 81.02  ? 159 SER   L CB  1 
ATOM   5243 N N   . GLN   D 4 161 ? 143.766 128.919 78.636  1.00 73.82  ? 160 GLN   L N   1 
ATOM   5244 C CA  . GLN   D 4 161 ? 144.307 129.735 79.713  1.00 71.73  ? 160 GLN   L CA  1 
ATOM   5245 C C   . GLN   D 4 161 ? 145.113 130.874 79.110  1.00 74.27  ? 160 GLN   L C   1 
ATOM   5246 O O   . GLN   D 4 161 ? 145.781 130.696 78.089  1.00 75.73  ? 160 GLN   L O   1 
ATOM   5247 C CB  . GLN   D 4 161 ? 145.192 128.914 80.660  1.00 73.53  ? 160 GLN   L CB  1 
ATOM   5248 C CG  . GLN   D 4 161 ? 144.424 128.055 81.649  1.00 78.48  ? 160 GLN   L CG  1 
ATOM   5249 C CD  . GLN   D 4 161 ? 145.316 127.487 82.735  1.00 77.96  ? 160 GLN   L CD  1 
ATOM   5250 O OE1 . GLN   D 4 161 ? 146.336 126.860 82.452  1.00 75.23  ? 160 GLN   L OE1 1 
ATOM   5251 N NE2 . GLN   D 4 161 ? 144.938 127.711 83.988  1.00 77.96  ? 160 GLN   L NE2 1 
ATOM   5252 N N   . GLU   D 4 162 ? 145.056 132.039 79.750  1.00 72.80  ? 161 GLU   L N   1 
ATOM   5253 C CA  . GLU   D 4 162 ? 145.703 133.242 79.249  1.00 66.85  ? 161 GLU   L CA  1 
ATOM   5254 C C   . GLU   D 4 162 ? 146.710 133.754 80.269  1.00 63.15  ? 161 GLU   L C   1 
ATOM   5255 O O   . GLU   D 4 162 ? 146.415 133.826 81.466  1.00 65.74  ? 161 GLU   L O   1 
ATOM   5256 C CB  . GLU   D 4 162 ? 144.690 134.359 78.921  1.00 70.46  ? 161 GLU   L CB  1 
ATOM   5257 C CG  . GLU   D 4 162 ? 143.634 134.692 79.990  1.00 75.53  ? 161 GLU   L CG  1 
ATOM   5258 C CD  . GLU   D 4 162 ? 142.726 133.530 80.354  1.00 80.55  ? 161 GLU   L CD  1 
ATOM   5259 O OE1 . GLU   D 4 162 ? 142.315 132.786 79.438  1.00 86.17  ? 161 GLU   L OE1 1 
ATOM   5260 O OE2 . GLU   D 4 162 ? 142.425 133.361 81.554  1.00 77.81  ? 161 GLU   L OE2 1 
ATOM   5261 N N   . SER   D 4 163 ? 147.898 134.108 79.786  1.00 61.07  ? 162 SER   L N   1 
ATOM   5262 C CA  . SER   D 4 163 ? 148.955 134.672 80.615  1.00 61.59  ? 162 SER   L CA  1 
ATOM   5263 C C   . SER   D 4 163 ? 149.379 136.007 80.026  1.00 65.74  ? 162 SER   L C   1 
ATOM   5264 O O   . SER   D 4 163 ? 149.682 136.092 78.831  1.00 70.98  ? 162 SER   L O   1 
ATOM   5265 C CB  . SER   D 4 163 ? 150.157 133.726 80.704  1.00 62.03  ? 162 SER   L CB  1 
ATOM   5266 O OG  . SER   D 4 163 ? 151.091 134.179 81.667  1.00 60.50  ? 162 SER   L OG  1 
ATOM   5267 N N   . VAL   D 4 164 ? 149.407 137.043 80.861  1.00 65.22  ? 163 VAL   L N   1 
ATOM   5268 C CA  . VAL   D 4 164 ? 149.738 138.396 80.433  1.00 60.04  ? 163 VAL   L CA  1 
ATOM   5269 C C   . VAL   D 4 164 ? 151.040 138.813 81.098  1.00 65.28  ? 163 VAL   L C   1 
ATOM   5270 O O   . VAL   D 4 164 ? 151.139 138.838 82.330  1.00 69.93  ? 163 VAL   L O   1 
ATOM   5271 C CB  . VAL   D 4 164 ? 148.613 139.392 80.777  1.00 54.98  ? 163 VAL   L CB  1 
ATOM   5272 C CG1 . VAL   D 4 164 ? 148.931 140.765 80.211  1.00 56.99  ? 163 VAL   L CG1 1 
ATOM   5273 C CG2 . VAL   D 4 164 ? 147.276 138.887 80.267  1.00 54.75  ? 163 VAL   L CG2 1 
ATOM   5274 N N   . THR   D 4 165 ? 152.036 139.144 80.283  1.00 60.52  ? 164 THR   L N   1 
ATOM   5275 C CA  . THR   D 4 165 ? 153.309 139.606 80.809  1.00 63.92  ? 164 THR   L CA  1 
ATOM   5276 C C   . THR   D 4 165 ? 153.213 141.070 81.228  1.00 67.49  ? 164 THR   L C   1 
ATOM   5277 O O   . THR   D 4 165 ? 152.320 141.809 80.807  1.00 67.20  ? 164 THR   L O   1 
ATOM   5278 C CB  . THR   D 4 165 ? 154.422 139.441 79.774  1.00 65.38  ? 164 THR   L CB  1 
ATOM   5279 O OG1 . THR   D 4 165 ? 153.929 139.806 78.480  1.00 73.55  ? 164 THR   L OG1 1 
ATOM   5280 C CG2 . THR   D 4 165 ? 154.911 138.003 79.735  1.00 66.91  ? 164 THR   L CG2 1 
ATOM   5281 N N   . GLU   D 4 166 ? 154.153 141.483 82.071  1.00 73.17  ? 165 GLU   L N   1 
ATOM   5282 C CA  . GLU   D 4 166 ? 154.244 142.879 82.462  1.00 78.47  ? 165 GLU   L CA  1 
ATOM   5283 C C   . GLU   D 4 166 ? 154.849 143.703 81.327  1.00 81.18  ? 165 GLU   L C   1 
ATOM   5284 O O   . GLU   D 4 166 ? 155.310 143.174 80.312  1.00 81.73  ? 165 GLU   L O   1 
ATOM   5285 C CB  . GLU   D 4 166 ? 155.072 143.027 83.737  1.00 79.79  ? 165 GLU   L CB  1 
ATOM   5286 N N   . GLN   D 4 167 ? 154.835 145.022 81.504  1.00 80.58  ? 166 GLN   L N   1 
ATOM   5287 C CA  . GLN   D 4 167 ? 155.395 145.909 80.494  1.00 85.13  ? 166 GLN   L CA  1 
ATOM   5288 C C   . GLN   D 4 167 ? 156.901 145.710 80.383  1.00 90.89  ? 166 GLN   L C   1 
ATOM   5289 O O   . GLN   D 4 167 ? 157.614 145.652 81.388  1.00 89.92  ? 166 GLN   L O   1 
ATOM   5290 C CB  . GLN   D 4 167 ? 155.081 147.364 80.837  1.00 85.45  ? 166 GLN   L CB  1 
ATOM   5291 C CG  . GLN   D 4 167 ? 153.611 147.722 80.725  1.00 80.37  ? 166 GLN   L CG  1 
ATOM   5292 C CD  . GLN   D 4 167 ? 153.388 149.070 80.070  1.00 78.48  ? 166 GLN   L CD  1 
ATOM   5293 O OE1 . GLN   D 4 167 ? 154.040 149.409 79.083  1.00 77.96  ? 166 GLN   L OE1 1 
ATOM   5294 N NE2 . GLN   D 4 167 ? 152.460 149.846 80.617  1.00 77.83  ? 166 GLN   L NE2 1 
ATOM   5295 N N   . ASP   D 4 168 ? 157.385 145.603 79.148  1.00 96.42  ? 167 ASP   L N   1 
ATOM   5296 C CA  . ASP   D 4 168 ? 158.815 145.475 78.917  1.00 100.64 ? 167 ASP   L CA  1 
ATOM   5297 C C   . ASP   D 4 168 ? 159.528 146.789 79.218  1.00 104.07 ? 167 ASP   L C   1 
ATOM   5298 O O   . ASP   D 4 168 ? 158.995 147.879 78.994  1.00 103.06 ? 167 ASP   L O   1 
ATOM   5299 C CB  . ASP   D 4 168 ? 159.093 145.045 77.476  1.00 99.13  ? 167 ASP   L CB  1 
ATOM   5300 C CG  . ASP   D 4 168 ? 158.250 143.862 77.048  1.00 93.86  ? 167 ASP   L CG  1 
ATOM   5301 O OD1 . ASP   D 4 168 ? 157.029 143.878 77.301  1.00 90.94  ? 167 ASP   L OD1 1 
ATOM   5302 O OD2 . ASP   D 4 168 ? 158.812 142.912 76.465  1.00 91.76  ? 167 ASP   L OD2 1 
ATOM   5303 N N   . SER   D 4 169 ? 160.751 146.674 79.738  1.00 103.78 ? 168 SER   L N   1 
ATOM   5304 C CA  . SER   D 4 169 ? 161.526 147.865 80.067  1.00 106.86 ? 168 SER   L CA  1 
ATOM   5305 C C   . SER   D 4 169 ? 161.951 148.616 78.811  1.00 113.45 ? 168 SER   L C   1 
ATOM   5306 O O   . SER   D 4 169 ? 162.110 149.842 78.838  1.00 114.09 ? 168 SER   L O   1 
ATOM   5307 C CB  . SER   D 4 169 ? 162.746 147.481 80.903  1.00 104.23 ? 168 SER   L CB  1 
ATOM   5308 N N   . LYS   D 4 170 ? 162.139 147.900 77.701  1.00 112.39 ? 169 LYS   L N   1 
ATOM   5309 C CA  . LYS   D 4 170 ? 162.644 148.530 76.486  1.00 106.56 ? 169 LYS   L CA  1 
ATOM   5310 C C   . LYS   D 4 170 ? 161.515 149.073 75.616  1.00 106.72 ? 169 LYS   L C   1 
ATOM   5311 O O   . LYS   D 4 170 ? 161.576 150.218 75.154  1.00 105.49 ? 169 LYS   L O   1 
ATOM   5312 C CB  . LYS   D 4 170 ? 163.496 147.534 75.697  1.00 104.09 ? 169 LYS   L CB  1 
ATOM   5313 N N   . ASP   D 4 171 ? 160.476 148.271 75.384  1.00 107.67 ? 170 ASP   L N   1 
ATOM   5314 C CA  . ASP   D 4 171 ? 159.425 148.626 74.440  1.00 108.98 ? 170 ASP   L CA  1 
ATOM   5315 C C   . ASP   D 4 171 ? 158.124 149.061 75.099  1.00 103.32 ? 170 ASP   L C   1 
ATOM   5316 O O   . ASP   D 4 171 ? 157.282 149.663 74.421  1.00 102.09 ? 170 ASP   L O   1 
ATOM   5317 C CB  . ASP   D 4 171 ? 159.143 147.449 73.496  1.00 104.53 ? 170 ASP   L CB  1 
ATOM   5318 N N   . SER   D 4 172 ? 157.936 148.785 76.391  1.00 97.54  ? 171 SER   L N   1 
ATOM   5319 C CA  . SER   D 4 172 ? 156.712 149.140 77.112  1.00 93.01  ? 171 SER   L CA  1 
ATOM   5320 C C   . SER   D 4 172 ? 155.472 148.591 76.407  1.00 92.19  ? 171 SER   L C   1 
ATOM   5321 O O   . SER   D 4 172 ? 154.463 149.280 76.241  1.00 91.73  ? 171 SER   L O   1 
ATOM   5322 C CB  . SER   D 4 172 ? 156.607 150.655 77.306  1.00 89.34  ? 171 SER   L CB  1 
ATOM   5323 O OG  . SER   D 4 172 ? 155.732 151.228 76.351  1.00 85.67  ? 171 SER   L OG  1 
ATOM   5324 N N   . THR   D 4 173 ? 155.559 147.333 75.982  1.00 92.43  ? 172 THR   L N   1 
ATOM   5325 C CA  . THR   D 4 173 ? 154.457 146.643 75.332  1.00 90.86  ? 172 THR   L CA  1 
ATOM   5326 C C   . THR   D 4 173 ? 154.057 145.438 76.171  1.00 88.93  ? 172 THR   L C   1 
ATOM   5327 O O   . THR   D 4 173 ? 154.602 145.199 77.251  1.00 87.66  ? 172 THR   L O   1 
ATOM   5328 C CB  . THR   D 4 173 ? 154.823 146.194 73.910  1.00 89.13  ? 172 THR   L CB  1 
ATOM   5329 O OG1 . THR   D 4 173 ? 156.107 145.558 73.923  1.00 90.13  ? 172 THR   L OG1 1 
ATOM   5330 C CG2 . THR   D 4 173 ? 154.863 147.388 72.969  1.00 90.85  ? 172 THR   L CG2 1 
ATOM   5331 N N   . TYR   D 4 174 ? 153.086 144.685 75.667  1.00 86.27  ? 173 TYR   L N   1 
ATOM   5332 C CA  . TYR   D 4 174 ? 152.614 143.480 76.331  1.00 78.04  ? 173 TYR   L CA  1 
ATOM   5333 C C   . TYR   D 4 174 ? 152.755 142.271 75.417  1.00 79.11  ? 173 TYR   L C   1 
ATOM   5334 O O   . TYR   D 4 174 ? 152.686 142.373 74.189  1.00 84.23  ? 173 TYR   L O   1 
ATOM   5335 C CB  . TYR   D 4 174 ? 151.154 143.623 76.770  1.00 72.03  ? 173 TYR   L CB  1 
ATOM   5336 C CG  . TYR   D 4 174 ? 150.916 144.722 77.774  1.00 69.74  ? 173 TYR   L CG  1 
ATOM   5337 C CD1 . TYR   D 4 174 ? 151.092 144.495 79.132  1.00 72.07  ? 173 TYR   L CD1 1 
ATOM   5338 C CD2 . TYR   D 4 174 ? 150.522 145.987 77.367  1.00 71.98  ? 173 TYR   L CD2 1 
ATOM   5339 C CE1 . TYR   D 4 174 ? 150.877 145.495 80.056  1.00 70.83  ? 173 TYR   L CE1 1 
ATOM   5340 C CE2 . TYR   D 4 174 ? 150.303 146.994 78.284  1.00 76.43  ? 173 TYR   L CE2 1 
ATOM   5341 C CZ  . TYR   D 4 174 ? 150.483 146.742 79.627  1.00 72.50  ? 173 TYR   L CZ  1 
ATOM   5342 O OH  . TYR   D 4 174 ? 150.269 147.742 80.545  1.00 71.31  ? 173 TYR   L OH  1 
ATOM   5343 N N   . SER   D 4 175 ? 152.963 141.116 76.042  1.00 73.00  ? 174 SER   L N   1 
ATOM   5344 C CA  . SER   D 4 175 ? 152.945 139.833 75.359  1.00 70.05  ? 174 SER   L CA  1 
ATOM   5345 C C   . SER   D 4 175 ? 151.940 138.929 76.055  1.00 68.21  ? 174 SER   L C   1 
ATOM   5346 O O   . SER   D 4 175 ? 152.002 138.741 77.274  1.00 69.75  ? 174 SER   L O   1 
ATOM   5347 C CB  . SER   D 4 175 ? 154.333 139.178 75.346  1.00 71.16  ? 174 SER   L CB  1 
ATOM   5348 O OG  . SER   D 4 175 ? 155.300 140.036 74.765  1.00 78.12  ? 174 SER   L OG  1 
ATOM   5349 N N   . LEU   D 4 176 ? 151.011 138.379 75.279  1.00 68.25  ? 175 LEU   L N   1 
ATOM   5350 C CA  . LEU   D 4 176 ? 149.945 137.538 75.805  1.00 63.72  ? 175 LEU   L CA  1 
ATOM   5351 C C   . LEU   D 4 176 ? 149.971 136.207 75.071  1.00 67.31  ? 175 LEU   L C   1 
ATOM   5352 O O   . LEU   D 4 176 ? 150.285 136.162 73.878  1.00 73.69  ? 175 LEU   L O   1 
ATOM   5353 C CB  . LEU   D 4 176 ? 148.578 138.217 75.642  1.00 57.00  ? 175 LEU   L CB  1 
ATOM   5354 C CG  . LEU   D 4 176 ? 147.386 137.708 76.457  1.00 53.10  ? 175 LEU   L CG  1 
ATOM   5355 C CD1 . LEU   D 4 176 ? 146.440 138.855 76.752  1.00 50.83  ? 175 LEU   L CD1 1 
ATOM   5356 C CD2 . LEU   D 4 176 ? 146.645 136.591 75.745  1.00 56.48  ? 175 LEU   L CD2 1 
ATOM   5357 N N   . SER   D 4 177 ? 149.655 135.128 75.783  1.00 62.83  ? 176 SER   L N   1 
ATOM   5358 C CA  . SER   D 4 177 ? 149.548 133.803 75.186  1.00 64.95  ? 176 SER   L CA  1 
ATOM   5359 C C   . SER   D 4 177 ? 148.256 133.158 75.660  1.00 61.46  ? 176 SER   L C   1 
ATOM   5360 O O   . SER   D 4 177 ? 147.958 133.165 76.858  1.00 63.36  ? 176 SER   L O   1 
ATOM   5361 C CB  . SER   D 4 177 ? 150.741 132.921 75.554  1.00 66.64  ? 176 SER   L CB  1 
ATOM   5362 O OG  . SER   D 4 177 ? 151.106 133.099 76.908  1.00 63.98  ? 176 SER   L OG  1 
ATOM   5363 N N   . SER   D 4 178 ? 147.494 132.607 74.722  1.00 63.03  ? 177 SER   L N   1 
ATOM   5364 C CA  . SER   D 4 178 ? 146.345 131.771 75.031  1.00 69.10  ? 177 SER   L CA  1 
ATOM   5365 C C   . SER   D 4 178 ? 146.694 130.335 74.671  1.00 75.88  ? 177 SER   L C   1 
ATOM   5366 O O   . SER   D 4 178 ? 147.028 130.044 73.517  1.00 76.65  ? 177 SER   L O   1 
ATOM   5367 C CB  . SER   D 4 178 ? 145.103 132.236 74.269  1.00 72.12  ? 177 SER   L CB  1 
ATOM   5368 O OG  . SER   D 4 178 ? 143.974 131.448 74.603  1.00 71.17  ? 177 SER   L OG  1 
ATOM   5369 N N   . THR   D 4 179 ? 146.627 129.444 75.656  1.00 74.71  ? 178 THR   L N   1 
ATOM   5370 C CA  . THR   D 4 179 ? 147.058 128.062 75.499  1.00 72.35  ? 178 THR   L CA  1 
ATOM   5371 C C   . THR   D 4 179 ? 145.842 127.150 75.497  1.00 75.98  ? 178 THR   L C   1 
ATOM   5372 O O   . THR   D 4 179 ? 145.076 127.129 76.466  1.00 71.97  ? 178 THR   L O   1 
ATOM   5373 C CB  . THR   D 4 179 ? 148.019 127.655 76.619  1.00 66.01  ? 178 THR   L CB  1 
ATOM   5374 O OG1 . THR   D 4 179 ? 147.408 127.909 77.889  1.00 59.03  ? 178 THR   L OG1 1 
ATOM   5375 C CG2 . THR   D 4 179 ? 149.313 128.445 76.523  1.00 67.11  ? 178 THR   L CG2 1 
ATOM   5376 N N   . LEU   D 4 180 ? 145.676 126.392 74.418  1.00 82.73  ? 179 LEU   L N   1 
ATOM   5377 C CA  . LEU   D 4 180 ? 144.569 125.457 74.277  1.00 83.21  ? 179 LEU   L CA  1 
ATOM   5378 C C   . LEU   D 4 180 ? 145.088 124.037 74.453  1.00 90.28  ? 179 LEU   L C   1 
ATOM   5379 O O   . LEU   D 4 180 ? 145.910 123.569 73.660  1.00 91.83  ? 179 LEU   L O   1 
ATOM   5380 C CB  . LEU   D 4 180 ? 143.895 125.613 72.913  1.00 81.43  ? 179 LEU   L CB  1 
ATOM   5381 C CG  . LEU   D 4 180 ? 143.114 124.408 72.387  1.00 82.51  ? 179 LEU   L CG  1 
ATOM   5382 C CD1 . LEU   D 4 180 ? 141.781 124.282 73.107  1.00 88.46  ? 179 LEU   L CD1 1 
ATOM   5383 C CD2 . LEU   D 4 180 ? 142.912 124.511 70.884  1.00 85.05  ? 179 LEU   L CD2 1 
ATOM   5384 N N   . THR   D 4 181 ? 144.608 123.359 75.492  1.00 96.48  ? 180 THR   L N   1 
ATOM   5385 C CA  . THR   D 4 181 ? 145.043 122.009 75.830  1.00 96.62  ? 180 THR   L CA  1 
ATOM   5386 C C   . THR   D 4 181 ? 143.867 121.055 75.664  1.00 101.24 ? 180 THR   L C   1 
ATOM   5387 O O   . THR   D 4 181 ? 142.783 121.302 76.204  1.00 98.79  ? 180 THR   L O   1 
ATOM   5388 C CB  . THR   D 4 181 ? 145.586 121.951 77.258  1.00 87.88  ? 180 THR   L CB  1 
ATOM   5389 O OG1 . THR   D 4 181 ? 146.657 122.892 77.403  1.00 82.90  ? 180 THR   L OG1 1 
ATOM   5390 C CG2 . THR   D 4 181 ? 146.098 120.559 77.575  1.00 94.86  ? 180 THR   L CG2 1 
ATOM   5391 N N   . LEU   D 4 182 ? 144.085 119.970 74.924  1.00 104.00 ? 181 LEU   L N   1 
ATOM   5392 C CA  . LEU   D 4 182 ? 143.041 118.998 74.635  1.00 106.28 ? 181 LEU   L CA  1 
ATOM   5393 C C   . LEU   D 4 182 ? 143.640 117.602 74.540  1.00 111.33 ? 181 LEU   L C   1 
ATOM   5394 O O   . LEU   D 4 182 ? 144.856 117.436 74.402  1.00 114.60 ? 181 LEU   L O   1 
ATOM   5395 C CB  . LEU   D 4 182 ? 142.302 119.339 73.334  1.00 105.35 ? 181 LEU   L CB  1 
ATOM   5396 C CG  . LEU   D 4 182 ? 141.188 120.380 73.457  1.00 103.63 ? 181 LEU   L CG  1 
ATOM   5397 C CD1 . LEU   D 4 182 ? 140.561 120.669 72.101  1.00 109.53 ? 181 LEU   L CD1 1 
ATOM   5398 C CD2 . LEU   D 4 182 ? 140.135 119.922 74.456  1.00 99.66  ? 181 LEU   L CD2 1 
ATOM   5399 N N   . SER   D 4 183 ? 142.769 116.598 74.620  1.00 110.98 ? 182 SER   L N   1 
ATOM   5400 C CA  . SER   D 4 183 ? 143.207 115.212 74.531  1.00 112.48 ? 182 SER   L CA  1 
ATOM   5401 C C   . SER   D 4 183 ? 143.648 114.878 73.110  1.00 119.50 ? 182 SER   L C   1 
ATOM   5402 O O   . SER   D 4 183 ? 143.260 115.536 72.142  1.00 121.95 ? 182 SER   L O   1 
ATOM   5403 C CB  . SER   D 4 183 ? 142.086 114.269 74.968  1.00 109.94 ? 182 SER   L CB  1 
ATOM   5404 N N   . LYS   D 4 184 ? 144.477 113.837 72.996  1.00 120.62 ? 183 LYS   L N   1 
ATOM   5405 C CA  . LYS   D 4 184 ? 145.018 113.457 71.694  1.00 122.17 ? 183 LYS   L CA  1 
ATOM   5406 C C   . LYS   D 4 184 ? 143.917 113.021 70.735  1.00 121.58 ? 183 LYS   L C   1 
ATOM   5407 O O   . LYS   D 4 184 ? 143.925 113.399 69.558  1.00 124.63 ? 183 LYS   L O   1 
ATOM   5408 C CB  . LYS   D 4 184 ? 146.051 112.344 71.863  1.00 123.07 ? 183 LYS   L CB  1 
ATOM   5409 C CG  . LYS   D 4 184 ? 146.718 111.914 70.566  1.00 125.07 ? 183 LYS   L CG  1 
ATOM   5410 C CD  . LYS   D 4 184 ? 147.430 110.582 70.725  1.00 121.38 ? 183 LYS   L CD  1 
ATOM   5411 C CE  . LYS   D 4 184 ? 148.238 110.241 69.485  1.00 126.47 ? 183 LYS   L CE  1 
ATOM   5412 N NZ  . LYS   D 4 184 ? 149.113 109.055 69.699  1.00 130.23 ? 183 LYS   L NZ  1 
ATOM   5413 N N   . ALA   D 4 185 ? 142.964 112.219 71.218  1.00 116.45 ? 184 ALA   L N   1 
ATOM   5414 C CA  . ALA   D 4 185 ? 141.908 111.719 70.342  1.00 116.99 ? 184 ALA   L CA  1 
ATOM   5415 C C   . ALA   D 4 185 ? 141.044 112.855 69.810  1.00 118.49 ? 184 ALA   L C   1 
ATOM   5416 O O   . ALA   D 4 185 ? 140.682 112.869 68.627  1.00 121.50 ? 184 ALA   L O   1 
ATOM   5417 C CB  . ALA   D 4 185 ? 141.052 110.694 71.085  1.00 119.13 ? 184 ALA   L CB  1 
ATOM   5418 N N   . ASP   D 4 186 ? 140.711 113.806 70.687  1.00 114.85 ? 185 ASP   L N   1 
ATOM   5419 C CA  . ASP   D 4 186 ? 139.897 114.976 70.259  1.00 117.86 ? 185 ASP   L CA  1 
ATOM   5420 C C   . ASP   D 4 186 ? 140.661 115.737 69.173  1.00 121.38 ? 185 ASP   L C   1 
ATOM   5421 O O   . ASP   D 4 186 ? 140.041 116.114 68.156  1.00 120.07 ? 185 ASP   L O   1 
ATOM   5422 C CB  . ASP   D 4 186 ? 139.545 115.868 71.437  1.00 114.76 ? 185 ASP   L CB  1 
ATOM   5423 C CG  . ASP   D 4 186 ? 138.521 116.955 71.141  1.00 113.71 ? 185 ASP   L CG  1 
ATOM   5424 O OD1 . ASP   D 4 186 ? 137.728 116.773 70.193  1.00 115.07 ? 185 ASP   L OD1 1 
ATOM   5425 O OD2 . ASP   D 4 186 ? 138.524 117.972 71.864  1.00 111.85 ? 185 ASP   L OD2 1 
ATOM   5426 N N   . TYR   D 4 187 ? 141.959 115.958 69.387  1.00 121.60 ? 186 TYR   L N   1 
ATOM   5427 C CA  . TYR   D 4 187 ? 142.769 116.660 68.397  1.00 119.68 ? 186 TYR   L CA  1 
ATOM   5428 C C   . TYR   D 4 187 ? 142.788 115.920 67.065  1.00 122.37 ? 186 TYR   L C   1 
ATOM   5429 O O   . TYR   D 4 187 ? 142.679 116.540 66.001  1.00 123.65 ? 186 TYR   L O   1 
ATOM   5430 C CB  . TYR   D 4 187 ? 144.191 116.847 68.925  1.00 118.64 ? 186 TYR   L CB  1 
ATOM   5431 C CG  . TYR   D 4 187 ? 145.150 117.437 67.915  1.00 122.09 ? 186 TYR   L CG  1 
ATOM   5432 C CD1 . TYR   D 4 187 ? 145.102 118.785 67.582  1.00 121.73 ? 186 TYR   L CD1 1 
ATOM   5433 C CD2 . TYR   D 4 187 ? 146.107 116.644 67.295  1.00 120.63 ? 186 TYR   L CD2 1 
ATOM   5434 C CE1 . TYR   D 4 187 ? 145.981 119.326 66.658  1.00 116.98 ? 186 TYR   L CE1 1 
ATOM   5435 C CE2 . TYR   D 4 187 ? 146.989 117.176 66.370  1.00 115.73 ? 186 TYR   L CE2 1 
ATOM   5436 C CZ  . TYR   D 4 187 ? 146.922 118.517 66.056  1.00 114.41 ? 186 TYR   L CZ  1 
ATOM   5437 O OH  . TYR   D 4 187 ? 147.797 119.052 65.137  1.00 112.13 ? 186 TYR   L OH  1 
ATOM   5438 N N   . GLU   D 4 188 ? 142.932 114.592 67.101  1.00 123.25 ? 187 GLU   L N   1 
ATOM   5439 C CA  . GLU   D 4 188 ? 142.932 113.820 65.861  1.00 125.25 ? 187 GLU   L CA  1 
ATOM   5440 C C   . GLU   D 4 188 ? 141.567 113.839 65.184  1.00 124.67 ? 187 GLU   L C   1 
ATOM   5441 O O   . GLU   D 4 188 ? 141.481 113.677 63.962  1.00 125.87 ? 187 GLU   L O   1 
ATOM   5442 C CB  . GLU   D 4 188 ? 143.371 112.380 66.131  1.00 124.47 ? 187 GLU   L CB  1 
ATOM   5443 C CG  . GLU   D 4 188 ? 144.756 112.252 66.744  1.00 124.08 ? 187 GLU   L CG  1 
ATOM   5444 C CD  . GLU   D 4 188 ? 145.860 112.246 65.704  1.00 125.51 ? 187 GLU   L CD  1 
ATOM   5445 O OE1 . GLU   D 4 188 ? 145.570 112.518 64.520  1.00 128.07 ? 187 GLU   L OE1 1 
ATOM   5446 O OE2 . GLU   D 4 188 ? 147.021 111.968 66.071  1.00 121.32 ? 187 GLU   L OE2 1 
ATOM   5447 N N   . LYS   D 4 189 ? 140.494 114.025 65.958  1.00 122.83 ? 188 LYS   L N   1 
ATOM   5448 C CA  . LYS   D 4 189 ? 139.160 114.076 65.366  1.00 124.24 ? 188 LYS   L CA  1 
ATOM   5449 C C   . LYS   D 4 189 ? 139.030 115.232 64.381  1.00 126.96 ? 188 LYS   L C   1 
ATOM   5450 O O   . LYS   D 4 189 ? 138.458 115.071 63.296  1.00 127.47 ? 188 LYS   L O   1 
ATOM   5451 C CB  . LYS   D 4 189 ? 138.098 114.191 66.461  1.00 121.15 ? 188 LYS   L CB  1 
ATOM   5452 C CG  . LYS   D 4 189 ? 137.856 112.911 67.239  1.00 121.70 ? 188 LYS   L CG  1 
ATOM   5453 C CD  . LYS   D 4 189 ? 136.942 113.157 68.428  1.00 120.89 ? 188 LYS   L CD  1 
ATOM   5454 C CE  . LYS   D 4 189 ? 136.708 111.881 69.218  1.00 122.19 ? 188 LYS   L CE  1 
ATOM   5455 N NZ  . LYS   D 4 189 ? 137.975 111.342 69.784  1.00 122.34 ? 188 LYS   L NZ  1 
ATOM   5456 N N   . HIS   D 4 190 ? 139.551 116.400 64.736  1.00 126.57 ? 189 HIS   L N   1 
ATOM   5457 C CA  . HIS   D 4 190 ? 139.450 117.586 63.900  1.00 125.78 ? 189 HIS   L CA  1 
ATOM   5458 C C   . HIS   D 4 190 ? 140.732 117.800 63.104  1.00 124.30 ? 189 HIS   L C   1 
ATOM   5459 O O   . HIS   D 4 190 ? 141.802 117.292 63.448  1.00 123.63 ? 189 HIS   L O   1 
ATOM   5460 C CB  . HIS   D 4 190 ? 139.147 118.823 64.750  1.00 125.72 ? 189 HIS   L CB  1 
ATOM   5461 C CG  . HIS   D 4 190 ? 137.787 118.807 65.373  1.00 127.34 ? 189 HIS   L CG  1 
ATOM   5462 N ND1 . HIS   D 4 190 ? 136.627 118.817 64.628  1.00 127.98 ? 189 HIS   L ND1 1 
ATOM   5463 C CD2 . HIS   D 4 190 ? 137.400 118.780 66.671  1.00 127.54 ? 189 HIS   L CD2 1 
ATOM   5464 C CE1 . HIS   D 4 190 ? 135.585 118.798 65.440  1.00 127.56 ? 189 HIS   L CE1 1 
ATOM   5465 N NE2 . HIS   D 4 190 ? 136.027 118.776 66.685  1.00 128.54 ? 189 HIS   L NE2 1 
ATOM   5466 N N   . LYS   D 4 191 ? 140.607 118.565 62.022  1.00 124.32 ? 190 LYS   L N   1 
ATOM   5467 C CA  . LYS   D 4 191 ? 141.731 118.878 61.151  1.00 125.36 ? 190 LYS   L CA  1 
ATOM   5468 C C   . LYS   D 4 191 ? 141.981 120.368 60.984  1.00 125.42 ? 190 LYS   L C   1 
ATOM   5469 O O   . LYS   D 4 191 ? 143.126 120.761 60.750  1.00 124.33 ? 190 LYS   L O   1 
ATOM   5470 C CB  . LYS   D 4 191 ? 141.522 118.253 59.762  1.00 121.59 ? 190 LYS   L CB  1 
ATOM   5471 N N   . VAL   D 4 192 ? 140.952 121.203 61.097  1.00 125.33 ? 191 VAL   L N   1 
ATOM   5472 C CA  . VAL   D 4 192 ? 141.079 122.648 60.951  1.00 124.83 ? 191 VAL   L CA  1 
ATOM   5473 C C   . VAL   D 4 192 ? 141.137 123.264 62.341  1.00 124.94 ? 191 VAL   L C   1 
ATOM   5474 O O   . VAL   D 4 192 ? 140.191 123.129 63.126  1.00 126.92 ? 191 VAL   L O   1 
ATOM   5475 C CB  . VAL   D 4 192 ? 139.915 123.242 60.136  1.00 126.66 ? 191 VAL   L CB  1 
ATOM   5476 C CG1 . VAL   D 4 192 ? 140.021 124.758 60.084  1.00 125.26 ? 191 VAL   L CG1 1 
ATOM   5477 C CG2 . VAL   D 4 192 ? 139.894 122.652 58.734  1.00 125.68 ? 191 VAL   L CG2 1 
ATOM   5478 N N   . TYR   D 4 193 ? 142.243 123.942 62.640  1.00 123.33 ? 192 TYR   L N   1 
ATOM   5479 C CA  . TYR   D 4 193 ? 142.462 124.563 63.940  1.00 116.87 ? 192 TYR   L CA  1 
ATOM   5480 C C   . TYR   D 4 193 ? 142.972 125.980 63.737  1.00 117.42 ? 192 TYR   L C   1 
ATOM   5481 O O   . TYR   D 4 193 ? 143.852 126.212 62.902  1.00 118.14 ? 192 TYR   L O   1 
ATOM   5482 C CB  . TYR   D 4 193 ? 143.458 123.758 64.778  1.00 115.69 ? 192 TYR   L CB  1 
ATOM   5483 C CG  . TYR   D 4 193 ? 142.810 122.839 65.787  1.00 120.04 ? 192 TYR   L CG  1 
ATOM   5484 C CD1 . TYR   D 4 193 ? 142.336 121.589 65.412  1.00 122.47 ? 192 TYR   L CD1 1 
ATOM   5485 C CD2 . TYR   D 4 193 ? 142.676 123.219 67.115  1.00 118.90 ? 192 TYR   L CD2 1 
ATOM   5486 C CE1 . TYR   D 4 193 ? 141.743 120.745 66.331  1.00 122.42 ? 192 TYR   L CE1 1 
ATOM   5487 C CE2 . TYR   D 4 193 ? 142.086 122.382 68.042  1.00 117.48 ? 192 TYR   L CE2 1 
ATOM   5488 C CZ  . TYR   D 4 193 ? 141.621 121.147 67.644  1.00 120.62 ? 192 TYR   L CZ  1 
ATOM   5489 O OH  . TYR   D 4 193 ? 141.032 120.309 68.563  1.00 120.97 ? 192 TYR   L OH  1 
ATOM   5490 N N   . ALA   D 4 194 ? 142.423 126.921 64.502  1.00 119.24 ? 193 ALA   L N   1 
ATOM   5491 C CA  . ALA   D 4 194 ? 142.811 128.318 64.378  1.00 117.23 ? 193 ALA   L CA  1 
ATOM   5492 C C   . ALA   D 4 194 ? 142.448 129.056 65.658  1.00 112.38 ? 193 ALA   L C   1 
ATOM   5493 O O   . ALA   D 4 194 ? 141.648 128.580 66.467  1.00 114.18 ? 193 ALA   L O   1 
ATOM   5494 C CB  . ALA   D 4 194 ? 142.140 128.978 63.170  1.00 113.30 ? 193 ALA   L CB  1 
ATOM   5495 N N   . CYS   D 4 195 ? 143.056 130.228 65.827  1.00 106.62 ? 194 CYS   L N   1 
ATOM   5496 C CA  . CYS   D 4 195 ? 142.741 131.140 66.919  1.00 106.68 ? 194 CYS   L CA  1 
ATOM   5497 C C   . CYS   D 4 195 ? 142.469 132.520 66.340  1.00 110.99 ? 194 CYS   L C   1 
ATOM   5498 O O   . CYS   D 4 195 ? 143.208 132.987 65.466  1.00 112.13 ? 194 CYS   L O   1 
ATOM   5499 C CB  . CYS   D 4 195 ? 143.877 131.200 67.946  1.00 100.46 ? 194 CYS   L CB  1 
ATOM   5500 S SG  . CYS   D 4 195 ? 145.467 131.783 67.312  1.00 109.85 ? 194 CYS   L SG  1 
ATOM   5501 N N   . GLU   D 4 196 ? 141.410 133.164 66.820  1.00 110.04 ? 195 GLU   L N   1 
ATOM   5502 C CA  . GLU   D 4 196 ? 140.989 134.469 66.330  1.00 106.72 ? 195 GLU   L CA  1 
ATOM   5503 C C   . GLU   D 4 196 ? 141.379 135.538 67.339  1.00 101.90 ? 195 GLU   L C   1 
ATOM   5504 O O   . GLU   D 4 196 ? 141.051 135.428 68.525  1.00 99.29  ? 195 GLU   L O   1 
ATOM   5505 C CB  . GLU   D 4 196 ? 139.480 134.498 66.076  1.00 104.47 ? 195 GLU   L CB  1 
ATOM   5506 C CG  . GLU   D 4 196 ? 138.897 135.893 65.937  1.00 107.16 ? 195 GLU   L CG  1 
ATOM   5507 C CD  . GLU   D 4 196 ? 137.382 135.890 65.923  1.00 106.77 ? 195 GLU   L CD  1 
ATOM   5508 O OE1 . GLU   D 4 196 ? 136.790 134.797 65.800  1.00 100.68 ? 195 GLU   L OE1 1 
ATOM   5509 O OE2 . GLU   D 4 196 ? 136.783 136.980 66.032  1.00 110.99 ? 195 GLU   L OE2 1 
ATOM   5510 N N   . VAL   D 4 197 ? 142.073 136.570 66.866  1.00 101.82 ? 196 VAL   L N   1 
ATOM   5511 C CA  . VAL   D 4 197 ? 142.592 137.639 67.710  1.00 100.01 ? 196 VAL   L CA  1 
ATOM   5512 C C   . VAL   D 4 197 ? 141.892 138.936 67.335  1.00 104.83 ? 196 VAL   L C   1 
ATOM   5513 O O   . VAL   D 4 197 ? 141.860 139.312 66.158  1.00 108.06 ? 196 VAL   L O   1 
ATOM   5514 C CB  . VAL   D 4 197 ? 144.118 137.781 67.565  1.00 93.39  ? 196 VAL   L CB  1 
ATOM   5515 C CG1 . VAL   D 4 197 ? 144.594 139.066 68.214  1.00 89.23  ? 196 VAL   L CG1 1 
ATOM   5516 C CG2 . VAL   D 4 197 ? 144.817 136.581 68.177  1.00 96.82  ? 196 VAL   L CG2 1 
ATOM   5517 N N   . THR   D 4 198 ? 141.336 139.617 68.335  1.00 103.21 ? 197 THR   L N   1 
ATOM   5518 C CA  . THR   D 4 198 ? 140.672 140.900 68.151  1.00 104.03 ? 197 THR   L CA  1 
ATOM   5519 C C   . THR   D 4 198 ? 141.397 141.958 68.970  1.00 99.33  ? 197 THR   L C   1 
ATOM   5520 O O   . THR   D 4 198 ? 141.651 141.758 70.163  1.00 96.66  ? 197 THR   L O   1 
ATOM   5521 C CB  . THR   D 4 198 ? 139.200 140.829 68.565  1.00 100.30 ? 197 THR   L CB  1 
ATOM   5522 N N   . HIS   D 4 199 ? 141.729 143.077 68.331  1.00 100.61 ? 198 HIS   L N   1 
ATOM   5523 C CA  . HIS   D 4 199 ? 142.418 144.175 68.992  1.00 101.89 ? 198 HIS   L CA  1 
ATOM   5524 C C   . HIS   D 4 199 ? 142.005 145.487 68.338  1.00 107.94 ? 198 HIS   L C   1 
ATOM   5525 O O   . HIS   D 4 199 ? 141.524 145.517 67.202  1.00 109.20 ? 198 HIS   L O   1 
ATOM   5526 C CB  . HIS   D 4 199 ? 143.941 143.993 68.940  1.00 99.00  ? 198 HIS   L CB  1 
ATOM   5527 C CG  . HIS   D 4 199 ? 144.692 144.941 69.822  1.00 94.17  ? 198 HIS   L CG  1 
ATOM   5528 N ND1 . HIS   D 4 199 ? 145.385 146.026 69.330  1.00 92.11  ? 198 HIS   L ND1 1 
ATOM   5529 C CD2 . HIS   D 4 199 ? 144.855 144.969 71.166  1.00 88.05  ? 198 HIS   L CD2 1 
ATOM   5530 C CE1 . HIS   D 4 199 ? 145.944 146.680 70.331  1.00 88.18  ? 198 HIS   L CE1 1 
ATOM   5531 N NE2 . HIS   D 4 199 ? 145.638 146.060 71.457  1.00 82.25  ? 198 HIS   L NE2 1 
ATOM   5532 N N   . GLN   D 4 200 ? 142.195 146.584 69.078  1.00 104.71 ? 199 GLN   L N   1 
ATOM   5533 C CA  . GLN   D 4 200 ? 141.818 147.899 68.567  1.00 101.70 ? 199 GLN   L CA  1 
ATOM   5534 C C   . GLN   D 4 200 ? 142.625 148.267 67.329  1.00 105.50 ? 199 GLN   L C   1 
ATOM   5535 O O   . GLN   D 4 200 ? 142.076 148.804 66.360  1.00 109.55 ? 199 GLN   L O   1 
ATOM   5536 C CB  . GLN   D 4 200 ? 142.000 148.956 69.655  1.00 99.24  ? 199 GLN   L CB  1 
ATOM   5537 C CG  . GLN   D 4 200 ? 140.896 148.972 70.697  1.00 103.76 ? 199 GLN   L CG  1 
ATOM   5538 C CD  . GLN   D 4 200 ? 140.771 150.314 71.390  1.00 103.65 ? 199 GLN   L CD  1 
ATOM   5539 O OE1 . GLN   D 4 200 ? 141.704 151.118 71.383  1.00 101.48 ? 199 GLN   L OE1 1 
ATOM   5540 N NE2 . GLN   D 4 200 ? 139.616 150.562 71.996  1.00 102.52 ? 199 GLN   L NE2 1 
ATOM   5541 N N   . GLY   D 4 201 ? 143.930 147.990 67.344  1.00 103.95 ? 200 GLY   L N   1 
ATOM   5542 C CA  . GLY   D 4 201 ? 144.759 148.318 66.196  1.00 104.05 ? 200 GLY   L CA  1 
ATOM   5543 C C   . GLY   D 4 201 ? 144.356 147.559 64.946  1.00 110.62 ? 200 GLY   L C   1 
ATOM   5544 O O   . GLY   D 4 201 ? 144.480 148.072 63.830  1.00 111.92 ? 200 GLY   L O   1 
ATOM   5545 N N   . LEU   D 4 202 ? 143.871 146.333 65.114  1.00 112.28 ? 201 LEU   L N   1 
ATOM   5546 C CA  . LEU   D 4 202 ? 143.453 145.530 63.975  1.00 116.61 ? 201 LEU   L CA  1 
ATOM   5547 C C   . LEU   D 4 202 ? 142.113 146.025 63.444  1.00 118.69 ? 201 LEU   L C   1 
ATOM   5548 O O   . LEU   D 4 202 ? 141.140 146.142 64.196  1.00 116.77 ? 201 LEU   L O   1 
ATOM   5549 C CB  . LEU   D 4 202 ? 143.352 144.061 64.380  1.00 115.07 ? 201 LEU   L CB  1 
ATOM   5550 C CG  . LEU   D 4 202 ? 144.640 143.429 64.912  1.00 109.73 ? 201 LEU   L CG  1 
ATOM   5551 C CD1 . LEU   D 4 202 ? 144.391 141.995 65.353  1.00 110.88 ? 201 LEU   L CD1 1 
ATOM   5552 C CD2 . LEU   D 4 202 ? 145.744 143.490 63.867  1.00 105.16 ? 201 LEU   L CD2 1 
ATOM   5553 N N   . SER   D 4 203 ? 142.065 146.325 62.144  1.00 119.17 ? 202 SER   L N   1 
ATOM   5554 C CA  . SER   D 4 203 ? 140.803 146.720 61.526  1.00 121.22 ? 202 SER   L CA  1 
ATOM   5555 C C   . SER   D 4 203 ? 139.811 145.565 61.522  1.00 122.83 ? 202 SER   L C   1 
ATOM   5556 O O   . SER   D 4 203 ? 138.613 145.764 61.758  1.00 120.79 ? 202 SER   L O   1 
ATOM   5557 C CB  . SER   D 4 203 ? 141.049 147.223 60.104  1.00 119.74 ? 202 SER   L CB  1 
ATOM   5558 N N   . SER   D 4 204 ? 140.290 144.358 61.257  1.00 121.24 ? 203 SER   L N   1 
ATOM   5559 C CA  . SER   D 4 204 ? 139.490 143.145 61.287  1.00 119.54 ? 203 SER   L CA  1 
ATOM   5560 C C   . SER   D 4 204 ? 140.235 142.109 62.115  1.00 119.53 ? 203 SER   L C   1 
ATOM   5561 O O   . SER   D 4 204 ? 141.464 142.165 62.225  1.00 117.72 ? 203 SER   L O   1 
ATOM   5562 C CB  . SER   D 4 204 ? 139.227 142.606 59.874  1.00 120.69 ? 203 SER   L CB  1 
ATOM   5563 N N   . PRO   D 4 205 ? 139.516 141.167 62.725  1.00 120.73 ? 204 PRO   L N   1 
ATOM   5564 C CA  . PRO   D 4 205 ? 140.194 140.123 63.504  1.00 114.52 ? 204 PRO   L CA  1 
ATOM   5565 C C   . PRO   D 4 205 ? 141.162 139.326 62.642  1.00 114.26 ? 204 PRO   L C   1 
ATOM   5566 O O   . PRO   D 4 205 ? 140.884 139.019 61.481  1.00 114.63 ? 204 PRO   L O   1 
ATOM   5567 C CB  . PRO   D 4 205 ? 139.038 139.251 64.007  1.00 111.58 ? 204 PRO   L CB  1 
ATOM   5568 C CG  . PRO   D 4 205 ? 137.862 140.168 64.023  1.00 112.76 ? 204 PRO   L CG  1 
ATOM   5569 C CD  . PRO   D 4 205 ? 138.051 141.080 62.845  1.00 119.46 ? 204 PRO   L CD  1 
ATOM   5570 N N   . VAL   D 4 206 ? 142.309 138.991 63.226  1.00 110.80 ? 205 VAL   L N   1 
ATOM   5571 C CA  . VAL   D 4 206 ? 143.366 138.255 62.544  1.00 112.45 ? 205 VAL   L CA  1 
ATOM   5572 C C   . VAL   D 4 206 ? 143.314 136.806 63.003  1.00 112.50 ? 205 VAL   L C   1 
ATOM   5573 O O   . VAL   D 4 206 ? 143.380 136.526 64.206  1.00 112.17 ? 205 VAL   L O   1 
ATOM   5574 C CB  . VAL   D 4 206 ? 144.749 138.872 62.815  1.00 108.81 ? 205 VAL   L CB  1 
ATOM   5575 C CG1 . VAL   D 4 206 ? 145.848 137.973 62.272  1.00 106.02 ? 205 VAL   L CG1 1 
ATOM   5576 C CG2 . VAL   D 4 206 ? 144.839 140.254 62.192  1.00 105.32 ? 205 VAL   L CG2 1 
ATOM   5577 N N   . THR   D 4 207 ? 143.196 135.890 62.047  1.00 108.68 ? 206 THR   L N   1 
ATOM   5578 C CA  . THR   D 4 207 ? 143.090 134.465 62.324  1.00 108.86 ? 206 THR   L CA  1 
ATOM   5579 C C   . THR   D 4 207 ? 144.238 133.734 61.647  1.00 112.38 ? 206 THR   L C   1 
ATOM   5580 O O   . THR   D 4 207 ? 144.476 133.918 60.448  1.00 116.04 ? 206 THR   L O   1 
ATOM   5581 C CB  . THR   D 4 207 ? 141.748 133.909 61.839  1.00 111.32 ? 206 THR   L CB  1 
ATOM   5582 O OG1 . THR   D 4 207 ? 140.678 134.681 62.398  1.00 109.14 ? 206 THR   L OG1 1 
ATOM   5583 C CG2 . THR   D 4 207 ? 141.590 132.459 62.260  1.00 113.39 ? 206 THR   L CG2 1 
ATOM   5584 N N   . LYS   D 4 208 ? 144.944 132.908 62.413  1.00 112.28 ? 207 LYS   L N   1 
ATOM   5585 C CA  . LYS   D 4 208 ? 146.042 132.098 61.905  1.00 114.38 ? 207 LYS   L CA  1 
ATOM   5586 C C   . LYS   D 4 208 ? 145.629 130.633 61.941  1.00 113.67 ? 207 LYS   L C   1 
ATOM   5587 O O   . LYS   D 4 208 ? 145.195 130.133 62.985  1.00 109.90 ? 207 LYS   L O   1 
ATOM   5588 C CB  . LYS   D 4 208 ? 147.313 132.319 62.727  1.00 106.69 ? 207 LYS   L CB  1 
ATOM   5589 C CG  . LYS   D 4 208 ? 147.773 133.767 62.772  1.00 97.77  ? 207 LYS   L CG  1 
ATOM   5590 C CD  . LYS   D 4 208 ? 148.184 134.261 61.397  1.00 97.70  ? 207 LYS   L CD  1 
ATOM   5591 C CE  . LYS   D 4 208 ? 148.680 135.696 61.453  1.00 94.89  ? 207 LYS   L CE  1 
ATOM   5592 N NZ  . LYS   D 4 208 ? 149.023 136.218 60.102  1.00 90.14  ? 207 LYS   L NZ  1 
ATOM   5593 N N   . SER   D 4 209 ? 145.769 129.950 60.808  1.00 113.79 ? 208 SER   L N   1 
ATOM   5594 C CA  . SER   D 4 209 ? 145.247 128.601 60.641  1.00 114.25 ? 208 SER   L CA  1 
ATOM   5595 C C   . SER   D 4 209 ? 146.359 127.650 60.227  1.00 118.51 ? 208 SER   L C   1 
ATOM   5596 O O   . SER   D 4 209 ? 147.319 128.050 59.562  1.00 124.68 ? 208 SER   L O   1 
ATOM   5597 C CB  . SER   D 4 209 ? 144.128 128.569 59.591  1.00 111.66 ? 208 SER   L CB  1 
ATOM   5598 O OG  . SER   D 4 209 ? 142.955 129.201 60.072  1.00 109.39 ? 208 SER   L OG  1 
ATOM   5599 N N   . PHE   D 4 210 ? 146.221 126.389 60.631  1.00 113.36 ? 209 PHE   L N   1 
ATOM   5600 C CA  . PHE   D 4 210 ? 147.112 125.313 60.222  1.00 113.69 ? 209 PHE   L CA  1 
ATOM   5601 C C   . PHE   D 4 210 ? 146.289 124.044 60.023  1.00 114.18 ? 209 PHE   L C   1 
ATOM   5602 O O   . PHE   D 4 210 ? 145.125 123.962 60.425  1.00 113.79 ? 209 PHE   L O   1 
ATOM   5603 C CB  . PHE   D 4 210 ? 148.239 125.101 61.243  1.00 112.49 ? 209 PHE   L CB  1 
ATOM   5604 C CG  . PHE   D 4 210 ? 147.773 124.574 62.571  1.00 110.66 ? 209 PHE   L CG  1 
ATOM   5605 C CD1 . PHE   D 4 210 ? 147.344 125.440 63.562  1.00 106.56 ? 209 PHE   L CD1 1 
ATOM   5606 C CD2 . PHE   D 4 210 ? 147.785 123.215 62.837  1.00 112.07 ? 209 PHE   L CD2 1 
ATOM   5607 C CE1 . PHE   D 4 210 ? 146.922 124.961 64.787  1.00 105.83 ? 209 PHE   L CE1 1 
ATOM   5608 C CE2 . PHE   D 4 210 ? 147.364 122.730 64.060  1.00 109.80 ? 209 PHE   L CE2 1 
ATOM   5609 C CZ  . PHE   D 4 210 ? 146.934 123.605 65.037  1.00 104.77 ? 209 PHE   L CZ  1 
ATOM   5610 N N   . ASN   D 4 211 ? 146.904 123.044 59.394  1.00 115.05 ? 210 ASN   L N   1 
ATOM   5611 C CA  . ASN   D 4 211 ? 146.221 121.799 59.061  1.00 116.35 ? 210 ASN   L CA  1 
ATOM   5612 C C   . ASN   D 4 211 ? 146.909 120.650 59.778  1.00 117.61 ? 210 ASN   L C   1 
ATOM   5613 O O   . ASN   D 4 211 ? 148.142 120.570 59.786  1.00 117.03 ? 210 ASN   L O   1 
ATOM   5614 C CB  . ASN   D 4 211 ? 146.213 121.560 57.547  1.00 113.75 ? 210 ASN   L CB  1 
ATOM   5615 N N   . ARG   D 4 212 ? 146.116 119.768 60.377  1.00 119.44 ? 211 ARG   L N   1 
ATOM   5616 C CA  . ARG   D 4 212 ? 146.646 118.610 61.087  1.00 117.07 ? 211 ARG   L CA  1 
ATOM   5617 C C   . ARG   D 4 212 ? 147.286 117.618 60.122  1.00 117.76 ? 211 ARG   L C   1 
ATOM   5618 O O   . ARG   D 4 212 ? 148.510 117.507 60.052  1.00 118.90 ? 211 ARG   L O   1 
ATOM   5619 C CB  . ARG   D 4 212 ? 145.539 117.924 61.889  1.00 116.58 ? 211 ARG   L CB  1 
ATOM   5620 C CG  . ARG   D 4 212 ? 146.011 116.736 62.711  1.00 117.33 ? 211 ARG   L CG  1 
ATOM   5621 C CD  . ARG   D 4 212 ? 144.857 116.097 63.467  1.00 119.23 ? 211 ARG   L CD  1 
ATOM   5622 N NE  . ARG   D 4 212 ? 143.798 115.645 62.572  1.00 123.22 ? 211 ARG   L NE  1 
ATOM   5623 C CZ  . ARG   D 4 212 ? 143.827 114.509 61.888  1.00 126.55 ? 211 ARG   L CZ  1 
ATOM   5624 N NH1 . ARG   D 4 212 ? 144.851 113.675 61.973  1.00 128.34 ? 211 ARG   L NH1 1 
ATOM   5625 N NH2 . ARG   D 4 212 ? 142.801 114.200 61.099  1.00 125.56 ? 211 ARG   L NH2 1 
HETATM 5626 C C01 . A1BNM E 5 .   ? 140.464 142.115 188.064 1.00 52.22  ? 501 A1BNM A C01 1 
HETATM 5627 C C02 . A1BNM E 5 .   ? 140.972 141.423 186.788 1.00 52.98  ? 501 A1BNM A C02 1 
HETATM 5628 C C04 . A1BNM E 5 .   ? 139.422 140.894 184.785 1.00 57.17  ? 501 A1BNM A C04 1 
HETATM 5629 C C05 . A1BNM E 5 .   ? 139.282 142.404 184.667 1.00 48.55  ? 501 A1BNM A C05 1 
HETATM 5630 C C06 . A1BNM E 5 .   ? 140.206 143.246 185.020 1.00 50.55  ? 501 A1BNM A C06 1 
HETATM 5631 C C07 . A1BNM E 5 .   ? 141.388 142.488 185.674 1.00 51.11  ? 501 A1BNM A C07 1 
HETATM 5632 C C08 . A1BNM E 5 .   ? 141.818 141.585 184.444 1.00 45.67  ? 501 A1BNM A C08 1 
HETATM 5633 C C09 . A1BNM E 5 .   ? 140.666 140.612 183.920 1.00 53.61  ? 501 A1BNM A C09 1 
HETATM 5634 C C10 . A1BNM E 5 .   ? 140.349 140.881 182.409 1.00 56.85  ? 501 A1BNM A C10 1 
HETATM 5635 C C12 . A1BNM E 5 .   ? 142.222 140.097 181.181 1.00 51.70  ? 501 A1BNM A C12 1 
HETATM 5636 C C14 . A1BNM E 5 .   ? 142.500 143.485 186.106 1.00 57.07  ? 501 A1BNM A C14 1 
HETATM 5637 C C15 . A1BNM E 5 .   ? 140.045 144.796 185.120 1.00 56.73  ? 501 A1BNM A C15 1 
HETATM 5638 C C16 . A1BNM E 5 .   ? 139.941 145.515 183.907 1.00 54.65  ? 501 A1BNM A C16 1 
HETATM 5639 C C17 . A1BNM E 5 .   ? 139.792 146.912 183.898 1.00 55.45  ? 501 A1BNM A C17 1 
HETATM 5640 C C18 . A1BNM E 5 .   ? 139.732 147.641 185.083 1.00 47.79  ? 501 A1BNM A C18 1 
HETATM 5641 C C19 . A1BNM E 5 .   ? 139.823 146.982 186.329 1.00 44.92  ? 501 A1BNM A C19 1 
HETATM 5642 C C21 . A1BNM E 5 .   ? 139.970 145.557 186.312 1.00 54.84  ? 501 A1BNM A C21 1 
HETATM 5643 C C22 . A1BNM E 5 .   ? 138.689 140.129 187.182 1.00 57.63  ? 501 A1BNM A C22 1 
HETATM 5644 C C23 . A1BNM E 5 .   ? 138.062 138.784 187.045 1.00 58.97  ? 501 A1BNM A C23 1 
HETATM 5645 C C24 . A1BNM E 5 .   ? 138.515 137.663 186.300 1.00 58.01  ? 501 A1BNM A C24 1 
HETATM 5646 C C27 . A1BNM E 5 .   ? 136.853 138.298 187.620 1.00 62.73  ? 501 A1BNM A C27 1 
HETATM 5647 C C28 . A1BNM E 5 .   ? 137.733 135.202 185.805 1.00 73.74  ? 501 A1BNM A C28 1 
HETATM 5648 C C29 . A1BNM E 5 .   ? 136.827 134.159 186.466 1.00 77.28  ? 501 A1BNM A C29 1 
HETATM 5649 N N03 . A1BNM E 5 .   ? 139.882 140.394 186.203 1.00 58.68  ? 501 A1BNM A N03 1 
HETATM 5650 N N25 . A1BNM E 5 .   ? 137.618 136.613 186.448 1.00 62.57  ? 501 A1BNM A N25 1 
HETATM 5651 N N26 . A1BNM E 5 .   ? 136.592 137.025 187.272 1.00 64.17  ? 501 A1BNM A N26 1 
HETATM 5652 O O11 . A1BNM E 5 .   ? 141.373 141.198 181.553 1.00 59.96  ? 501 A1BNM A O11 1 
HETATM 5653 O O13 . A1BNM E 5 .   ? 139.238 140.793 182.026 1.00 60.21  ? 501 A1BNM A O13 1 
HETATM 5654 O O20 . A1BNM E 5 .   ? 139.772 147.634 187.515 1.00 48.06  ? 501 A1BNM A O20 1 
# 
