data_9MNH
# 
_entry.id   9MNH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9MNH         pdb_00009mnh 10.2210/pdb9mnh/pdb 
WWPDB D_1000291136 ?            ?                   
EMDB  EMD-48423    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9MNH 
_pdbx_database_status.recvd_initial_deposition_date   2024-12-21 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Angavokely virus (AngV) fusion (F) protein ectodomain in pre-fusion conformation' 
_pdbx_database_related.db_id          EMD-48423 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              priyamvada.acharya@duke.edu 
_pdbx_contact_author.name_first         Priyamvada 
_pdbx_contact_author.name_last          Acharya 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0089-277X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lella, M.'   1 0000-0002-7374-9528 
'Acharya, P.' 2 0000-0002-0089-277X 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural and Antigenic Characterization of Novel and Diverse Henipavirus Glycoproteins.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.12.11.627382 
_citation.pdbx_database_id_PubMed   39713338 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'May, A.J.'        1  ? 
primary 'Lella, M.'        2  ? 
primary 'Lindenberger, J.' 3  ? 
primary 'Berkman, A.'      4  ? 
primary 'Kumar, U.'        5  ? 
primary 'Dutta, M.'        6  ? 
primary 'Barr, M.'         7  ? 
primary 'Parks, R.'        8  ? 
primary 'Newman, A.'       9  ? 
primary 'Huang, X.'        10 ? 
primary 'Song, K.'         11 ? 
primary 'Ilevbare, V.'     12 ? 
primary 'Sammour, S.'      13 ? 
primary 'Park, C.S.'       14 ? 
primary 'Adhikari, R.D.'   15 ? 
primary 'Devkota, P.'      16 ? 
primary 'Janowska, K.'     17 ? 
primary 'Liu, Y.'          18 ? 
primary 'Scapellato, G.'   19 ? 
primary 'Spence, T.N.'     20 ? 
primary 'Mansouri, K.'     21 ? 
primary 'Edwards, R.J.'    22 ? 
primary 'Saunders, K.O.'   23 ? 
primary 'Haynes, B.F.'     24 ? 
primary 'Acharya, P.'      25 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Fusion Protein' 58587.699 3 ? ? Ectodomain 
;Pre-fusion conformation.
C-terminal foldon trimerization domain followed by HRV3C protease site, His-tag, and two streptavidin tags separated by GS linker.
;
2 branched    man 
'beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 586.542   3 ? 
? ?          ? 
3 branched    man 
;beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
;
732.682   3 ? ? ?          ? 
4 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   9 ? ? ?          ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;VDFERLASIGGIKGHSKLYKIKGHPTTKDIVIKLVPNLNNLTVCSEMSIDGYLNLINAVIIPISQSLELMRNNVKDGTPN
ENIFGAIVAGAALGIATAAQVTSVVALHKSNQNAAKINSLRDSITKTNQAVEQLSLGVQETVSVLMGLQDQINTNLVPKI
NILSCKQLSNTLNIMLLQYYSQILTVFGPNLRDPATVPVSIQALSQLFEGNLELLTSSLGISSTDFNDLLTGKLITGSII
WADTQGHYLILRVNIPDLIEVPGAVIQEFIKIGYNFGGSLWMPTIPNKIIIRGYHLSLIDSTNCIITDNSYVCDRDYSLP
MNPILRECFEGNTSSCGREMVLNSYIPLYALSEGVIYANCLATSCKCATTNKPIVQSTSTVITMIDNSKCPVVEVGKQMI
SVGSYLGQVSPNNLTIEIGPPVYTEPVDITNQLGNINETLSKTLDLIKQSNSILDMITGGLGSGYIPEAPRDGQAYVRKD
GEWVLLSTFLGRSLEVLFQGPGHHHHHHHHSAWSHPQFEKGGGSGGGGSGGSAWSHPQFEK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;VDFERLASIGGIKGHSKLYKIKGHPTTKDIVIKLVPNLNNLTVCSEMSIDGYLNLINAVIIPISQSLELMRNNVKDGTPN
ENIFGAIVAGAALGIATAAQVTSVVALHKSNQNAAKINSLRDSITKTNQAVEQLSLGVQETVSVLMGLQDQINTNLVPKI
NILSCKQLSNTLNIMLLQYYSQILTVFGPNLRDPATVPVSIQALSQLFEGNLELLTSSLGISSTDFNDLLTGKLITGSII
WADTQGHYLILRVNIPDLIEVPGAVIQEFIKIGYNFGGSLWMPTIPNKIIIRGYHLSLIDSTNCIITDNSYVCDRDYSLP
MNPILRECFEGNTSSCGREMVLNSYIPLYALSEGVIYANCLATSCKCATTNKPIVQSTSTVITMIDNSKCPVVEVGKQMI
SVGSYLGQVSPNNLTIEIGPPVYTEPVDITNQLGNINETLSKTLDLIKQSNSILDMITGGLGSGYIPEAPRDGQAYVRKD
GEWVLLSTFLGRSLEVLFQGPGHHHHHHHHSAWSHPQFEKGGGSGGGGSGGSAWSHPQFEK
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   ASP n 
1 3   PHE n 
1 4   GLU n 
1 5   ARG n 
1 6   LEU n 
1 7   ALA n 
1 8   SER n 
1 9   ILE n 
1 10  GLY n 
1 11  GLY n 
1 12  ILE n 
1 13  LYS n 
1 14  GLY n 
1 15  HIS n 
1 16  SER n 
1 17  LYS n 
1 18  LEU n 
1 19  TYR n 
1 20  LYS n 
1 21  ILE n 
1 22  LYS n 
1 23  GLY n 
1 24  HIS n 
1 25  PRO n 
1 26  THR n 
1 27  THR n 
1 28  LYS n 
1 29  ASP n 
1 30  ILE n 
1 31  VAL n 
1 32  ILE n 
1 33  LYS n 
1 34  LEU n 
1 35  VAL n 
1 36  PRO n 
1 37  ASN n 
1 38  LEU n 
1 39  ASN n 
1 40  ASN n 
1 41  LEU n 
1 42  THR n 
1 43  VAL n 
1 44  CYS n 
1 45  SER n 
1 46  GLU n 
1 47  MET n 
1 48  SER n 
1 49  ILE n 
1 50  ASP n 
1 51  GLY n 
1 52  TYR n 
1 53  LEU n 
1 54  ASN n 
1 55  LEU n 
1 56  ILE n 
1 57  ASN n 
1 58  ALA n 
1 59  VAL n 
1 60  ILE n 
1 61  ILE n 
1 62  PRO n 
1 63  ILE n 
1 64  SER n 
1 65  GLN n 
1 66  SER n 
1 67  LEU n 
1 68  GLU n 
1 69  LEU n 
1 70  MET n 
1 71  ARG n 
1 72  ASN n 
1 73  ASN n 
1 74  VAL n 
1 75  LYS n 
1 76  ASP n 
1 77  GLY n 
1 78  THR n 
1 79  PRO n 
1 80  ASN n 
1 81  GLU n 
1 82  ASN n 
1 83  ILE n 
1 84  PHE n 
1 85  GLY n 
1 86  ALA n 
1 87  ILE n 
1 88  VAL n 
1 89  ALA n 
1 90  GLY n 
1 91  ALA n 
1 92  ALA n 
1 93  LEU n 
1 94  GLY n 
1 95  ILE n 
1 96  ALA n 
1 97  THR n 
1 98  ALA n 
1 99  ALA n 
1 100 GLN n 
1 101 VAL n 
1 102 THR n 
1 103 SER n 
1 104 VAL n 
1 105 VAL n 
1 106 ALA n 
1 107 LEU n 
1 108 HIS n 
1 109 LYS n 
1 110 SER n 
1 111 ASN n 
1 112 GLN n 
1 113 ASN n 
1 114 ALA n 
1 115 ALA n 
1 116 LYS n 
1 117 ILE n 
1 118 ASN n 
1 119 SER n 
1 120 LEU n 
1 121 ARG n 
1 122 ASP n 
1 123 SER n 
1 124 ILE n 
1 125 THR n 
1 126 LYS n 
1 127 THR n 
1 128 ASN n 
1 129 GLN n 
1 130 ALA n 
1 131 VAL n 
1 132 GLU n 
1 133 GLN n 
1 134 LEU n 
1 135 SER n 
1 136 LEU n 
1 137 GLY n 
1 138 VAL n 
1 139 GLN n 
1 140 GLU n 
1 141 THR n 
1 142 VAL n 
1 143 SER n 
1 144 VAL n 
1 145 LEU n 
1 146 MET n 
1 147 GLY n 
1 148 LEU n 
1 149 GLN n 
1 150 ASP n 
1 151 GLN n 
1 152 ILE n 
1 153 ASN n 
1 154 THR n 
1 155 ASN n 
1 156 LEU n 
1 157 VAL n 
1 158 PRO n 
1 159 LYS n 
1 160 ILE n 
1 161 ASN n 
1 162 ILE n 
1 163 LEU n 
1 164 SER n 
1 165 CYS n 
1 166 LYS n 
1 167 GLN n 
1 168 LEU n 
1 169 SER n 
1 170 ASN n 
1 171 THR n 
1 172 LEU n 
1 173 ASN n 
1 174 ILE n 
1 175 MET n 
1 176 LEU n 
1 177 LEU n 
1 178 GLN n 
1 179 TYR n 
1 180 TYR n 
1 181 SER n 
1 182 GLN n 
1 183 ILE n 
1 184 LEU n 
1 185 THR n 
1 186 VAL n 
1 187 PHE n 
1 188 GLY n 
1 189 PRO n 
1 190 ASN n 
1 191 LEU n 
1 192 ARG n 
1 193 ASP n 
1 194 PRO n 
1 195 ALA n 
1 196 THR n 
1 197 VAL n 
1 198 PRO n 
1 199 VAL n 
1 200 SER n 
1 201 ILE n 
1 202 GLN n 
1 203 ALA n 
1 204 LEU n 
1 205 SER n 
1 206 GLN n 
1 207 LEU n 
1 208 PHE n 
1 209 GLU n 
1 210 GLY n 
1 211 ASN n 
1 212 LEU n 
1 213 GLU n 
1 214 LEU n 
1 215 LEU n 
1 216 THR n 
1 217 SER n 
1 218 SER n 
1 219 LEU n 
1 220 GLY n 
1 221 ILE n 
1 222 SER n 
1 223 SER n 
1 224 THR n 
1 225 ASP n 
1 226 PHE n 
1 227 ASN n 
1 228 ASP n 
1 229 LEU n 
1 230 LEU n 
1 231 THR n 
1 232 GLY n 
1 233 LYS n 
1 234 LEU n 
1 235 ILE n 
1 236 THR n 
1 237 GLY n 
1 238 SER n 
1 239 ILE n 
1 240 ILE n 
1 241 TRP n 
1 242 ALA n 
1 243 ASP n 
1 244 THR n 
1 245 GLN n 
1 246 GLY n 
1 247 HIS n 
1 248 TYR n 
1 249 LEU n 
1 250 ILE n 
1 251 LEU n 
1 252 ARG n 
1 253 VAL n 
1 254 ASN n 
1 255 ILE n 
1 256 PRO n 
1 257 ASP n 
1 258 LEU n 
1 259 ILE n 
1 260 GLU n 
1 261 VAL n 
1 262 PRO n 
1 263 GLY n 
1 264 ALA n 
1 265 VAL n 
1 266 ILE n 
1 267 GLN n 
1 268 GLU n 
1 269 PHE n 
1 270 ILE n 
1 271 LYS n 
1 272 ILE n 
1 273 GLY n 
1 274 TYR n 
1 275 ASN n 
1 276 PHE n 
1 277 GLY n 
1 278 GLY n 
1 279 SER n 
1 280 LEU n 
1 281 TRP n 
1 282 MET n 
1 283 PRO n 
1 284 THR n 
1 285 ILE n 
1 286 PRO n 
1 287 ASN n 
1 288 LYS n 
1 289 ILE n 
1 290 ILE n 
1 291 ILE n 
1 292 ARG n 
1 293 GLY n 
1 294 TYR n 
1 295 HIS n 
1 296 LEU n 
1 297 SER n 
1 298 LEU n 
1 299 ILE n 
1 300 ASP n 
1 301 SER n 
1 302 THR n 
1 303 ASN n 
1 304 CYS n 
1 305 ILE n 
1 306 ILE n 
1 307 THR n 
1 308 ASP n 
1 309 ASN n 
1 310 SER n 
1 311 TYR n 
1 312 VAL n 
1 313 CYS n 
1 314 ASP n 
1 315 ARG n 
1 316 ASP n 
1 317 TYR n 
1 318 SER n 
1 319 LEU n 
1 320 PRO n 
1 321 MET n 
1 322 ASN n 
1 323 PRO n 
1 324 ILE n 
1 325 LEU n 
1 326 ARG n 
1 327 GLU n 
1 328 CYS n 
1 329 PHE n 
1 330 GLU n 
1 331 GLY n 
1 332 ASN n 
1 333 THR n 
1 334 SER n 
1 335 SER n 
1 336 CYS n 
1 337 GLY n 
1 338 ARG n 
1 339 GLU n 
1 340 MET n 
1 341 VAL n 
1 342 LEU n 
1 343 ASN n 
1 344 SER n 
1 345 TYR n 
1 346 ILE n 
1 347 PRO n 
1 348 LEU n 
1 349 TYR n 
1 350 ALA n 
1 351 LEU n 
1 352 SER n 
1 353 GLU n 
1 354 GLY n 
1 355 VAL n 
1 356 ILE n 
1 357 TYR n 
1 358 ALA n 
1 359 ASN n 
1 360 CYS n 
1 361 LEU n 
1 362 ALA n 
1 363 THR n 
1 364 SER n 
1 365 CYS n 
1 366 LYS n 
1 367 CYS n 
1 368 ALA n 
1 369 THR n 
1 370 THR n 
1 371 ASN n 
1 372 LYS n 
1 373 PRO n 
1 374 ILE n 
1 375 VAL n 
1 376 GLN n 
1 377 SER n 
1 378 THR n 
1 379 SER n 
1 380 THR n 
1 381 VAL n 
1 382 ILE n 
1 383 THR n 
1 384 MET n 
1 385 ILE n 
1 386 ASP n 
1 387 ASN n 
1 388 SER n 
1 389 LYS n 
1 390 CYS n 
1 391 PRO n 
1 392 VAL n 
1 393 VAL n 
1 394 GLU n 
1 395 VAL n 
1 396 GLY n 
1 397 LYS n 
1 398 GLN n 
1 399 MET n 
1 400 ILE n 
1 401 SER n 
1 402 VAL n 
1 403 GLY n 
1 404 SER n 
1 405 TYR n 
1 406 LEU n 
1 407 GLY n 
1 408 GLN n 
1 409 VAL n 
1 410 SER n 
1 411 PRO n 
1 412 ASN n 
1 413 ASN n 
1 414 LEU n 
1 415 THR n 
1 416 ILE n 
1 417 GLU n 
1 418 ILE n 
1 419 GLY n 
1 420 PRO n 
1 421 PRO n 
1 422 VAL n 
1 423 TYR n 
1 424 THR n 
1 425 GLU n 
1 426 PRO n 
1 427 VAL n 
1 428 ASP n 
1 429 ILE n 
1 430 THR n 
1 431 ASN n 
1 432 GLN n 
1 433 LEU n 
1 434 GLY n 
1 435 ASN n 
1 436 ILE n 
1 437 ASN n 
1 438 GLU n 
1 439 THR n 
1 440 LEU n 
1 441 SER n 
1 442 LYS n 
1 443 THR n 
1 444 LEU n 
1 445 ASP n 
1 446 LEU n 
1 447 ILE n 
1 448 LYS n 
1 449 GLN n 
1 450 SER n 
1 451 ASN n 
1 452 SER n 
1 453 ILE n 
1 454 LEU n 
1 455 ASP n 
1 456 MET n 
1 457 ILE n 
1 458 THR n 
1 459 GLY n 
1 460 GLY n 
1 461 LEU n 
1 462 GLY n 
1 463 SER n 
1 464 GLY n 
1 465 TYR n 
1 466 ILE n 
1 467 PRO n 
1 468 GLU n 
1 469 ALA n 
1 470 PRO n 
1 471 ARG n 
1 472 ASP n 
1 473 GLY n 
1 474 GLN n 
1 475 ALA n 
1 476 TYR n 
1 477 VAL n 
1 478 ARG n 
1 479 LYS n 
1 480 ASP n 
1 481 GLY n 
1 482 GLU n 
1 483 TRP n 
1 484 VAL n 
1 485 LEU n 
1 486 LEU n 
1 487 SER n 
1 488 THR n 
1 489 PHE n 
1 490 LEU n 
1 491 GLY n 
1 492 ARG n 
1 493 SER n 
1 494 LEU n 
1 495 GLU n 
1 496 VAL n 
1 497 LEU n 
1 498 PHE n 
1 499 GLN n 
1 500 GLY n 
1 501 PRO n 
1 502 GLY n 
1 503 HIS n 
1 504 HIS n 
1 505 HIS n 
1 506 HIS n 
1 507 HIS n 
1 508 HIS n 
1 509 HIS n 
1 510 HIS n 
1 511 SER n 
1 512 ALA n 
1 513 TRP n 
1 514 SER n 
1 515 HIS n 
1 516 PRO n 
1 517 GLN n 
1 518 PHE n 
1 519 GLU n 
1 520 LYS n 
1 521 GLY n 
1 522 GLY n 
1 523 GLY n 
1 524 SER n 
1 525 GLY n 
1 526 GLY n 
1 527 GLY n 
1 528 GLY n 
1 529 SER n 
1 530 GLY n 
1 531 GLY n 
1 532 SER n 
1 533 ALA n 
1 534 TRP n 
1 535 SER n 
1 536 HIS n 
1 537 PRO n 
1 538 GLN n 
1 539 PHE n 
1 540 GLU n 
1 541 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   541 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Angavokely henipavirus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2974046 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_branch.entity_id 
_pdbx_entity_branch.type 
2 oligosaccharide 
3 oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DManpb1-4DGlcpNAcb1-4DGlcpNAcb1-ROH                                                                 
'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/2,3,2/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5]/1-1-2/a4-b1_b4-c1'                        WURCS PDB2Glycan 1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}}'                                  LINUCS PDB-CARE   ?     
4 3 'DManpb1-4DGlcpNAcb1-4[LFucpa1-6]DGlcpNAcb1-ROH'                                                    
'Glycam Condensed Sequence' GMML       1.0   
5 3 'WURCS=2.0/3,4,3/[a2122h-1b_1-5_2*NCC/3=O][a1122h-1b_1-5][a1221m-1a_1-5]/1-1-2-3/a4-b1_a6-d1_b4-c1' WURCS PDB2Glycan 1.1.0 
6 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{[(4+1)][b-D-Manp]{}}[(6+1)][a-L-Fucp]{}}'               LINUCS PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
2 2 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
3 3 2 NAG C1 O1 1 NAG O4 HO4 sing ? 
4 3 3 BMA C1 O1 2 NAG O4 HO4 sing ? 
5 3 4 FUC C1 O1 1 NAG O6 HO6 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'           y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'           y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'           y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'           y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
BMA 'D-saccharide, beta linking'  . beta-D-mannopyranose                     'beta-D-mannose; D-mannose; mannose' 'C6 H12 O6'      
180.156 
CYS 'L-peptide linking'           y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
FUC 'L-saccharide, alpha linking' . alpha-L-fucopyranose                     
'alpha-L-fucose; 6-deoxy-alpha-L-galactopyranose; L-fucose; fucose' 'C6 H12 O5'      164.156 
GLN 'L-peptide linking'           y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'           y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'             y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'           y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'           y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'           y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'           y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'           y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking'  . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'           y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'           y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'           y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'           y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'           y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'           y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'           y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BMA 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DManpb                         
BMA 'COMMON NAME'                         GMML     1.0 b-D-mannopyranose              
BMA 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Manp                       
BMA 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Man                            
FUC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 LFucpa                         
FUC 'COMMON NAME'                         GMML     1.0 a-L-fucopyranose               
FUC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 a-L-Fucp                       
FUC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Fuc                            
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   22  22  VAL VAL A . n 
A 1 2   ASP 2   23  23  ASP ASP A . n 
A 1 3   PHE 3   24  24  PHE PHE A . n 
A 1 4   GLU 4   25  25  GLU GLU A . n 
A 1 5   ARG 5   26  26  ARG ARG A . n 
A 1 6   LEU 6   27  27  LEU LEU A . n 
A 1 7   ALA 7   28  28  ALA ALA A . n 
A 1 8   SER 8   29  29  SER SER A . n 
A 1 9   ILE 9   30  30  ILE ILE A . n 
A 1 10  GLY 10  31  31  GLY GLY A . n 
A 1 11  GLY 11  32  32  GLY GLY A . n 
A 1 12  ILE 12  33  33  ILE ILE A . n 
A 1 13  LYS 13  34  34  LYS LYS A . n 
A 1 14  GLY 14  35  35  GLY GLY A . n 
A 1 15  HIS 15  36  36  HIS HIS A . n 
A 1 16  SER 16  37  37  SER SER A . n 
A 1 17  LYS 17  38  38  LYS LYS A . n 
A 1 18  LEU 18  39  39  LEU LEU A . n 
A 1 19  TYR 19  40  40  TYR TYR A . n 
A 1 20  LYS 20  41  41  LYS LYS A . n 
A 1 21  ILE 21  42  42  ILE ILE A . n 
A 1 22  LYS 22  43  43  LYS LYS A . n 
A 1 23  GLY 23  44  44  GLY GLY A . n 
A 1 24  HIS 24  45  45  HIS HIS A . n 
A 1 25  PRO 25  46  46  PRO PRO A . n 
A 1 26  THR 26  47  47  THR THR A . n 
A 1 27  THR 27  48  48  THR THR A . n 
A 1 28  LYS 28  49  49  LYS LYS A . n 
A 1 29  ASP 29  50  50  ASP ASP A . n 
A 1 30  ILE 30  51  51  ILE ILE A . n 
A 1 31  VAL 31  52  52  VAL VAL A . n 
A 1 32  ILE 32  53  53  ILE ILE A . n 
A 1 33  LYS 33  54  54  LYS LYS A . n 
A 1 34  LEU 34  55  55  LEU LEU A . n 
A 1 35  VAL 35  56  56  VAL VAL A . n 
A 1 36  PRO 36  57  57  PRO PRO A . n 
A 1 37  ASN 37  58  58  ASN ASN A . n 
A 1 38  LEU 38  59  59  LEU LEU A . n 
A 1 39  ASN 39  60  60  ASN ASN A . n 
A 1 40  ASN 40  61  61  ASN ASN A . n 
A 1 41  LEU 41  62  62  LEU LEU A . n 
A 1 42  THR 42  63  63  THR THR A . n 
A 1 43  VAL 43  64  64  VAL VAL A . n 
A 1 44  CYS 44  65  65  CYS CYS A . n 
A 1 45  SER 45  66  66  SER SER A . n 
A 1 46  GLU 46  67  67  GLU GLU A . n 
A 1 47  MET 47  68  68  MET MET A . n 
A 1 48  SER 48  69  69  SER SER A . n 
A 1 49  ILE 49  70  70  ILE ILE A . n 
A 1 50  ASP 50  71  71  ASP ASP A . n 
A 1 51  GLY 51  72  72  GLY GLY A . n 
A 1 52  TYR 52  73  73  TYR TYR A . n 
A 1 53  LEU 53  74  74  LEU LEU A . n 
A 1 54  ASN 54  75  75  ASN ASN A . n 
A 1 55  LEU 55  76  76  LEU LEU A . n 
A 1 56  ILE 56  77  77  ILE ILE A . n 
A 1 57  ASN 57  78  78  ASN ASN A . n 
A 1 58  ALA 58  79  79  ALA ALA A . n 
A 1 59  VAL 59  80  80  VAL VAL A . n 
A 1 60  ILE 60  81  81  ILE ILE A . n 
A 1 61  ILE 61  82  82  ILE ILE A . n 
A 1 62  PRO 62  83  83  PRO PRO A . n 
A 1 63  ILE 63  84  84  ILE ILE A . n 
A 1 64  SER 64  85  85  SER SER A . n 
A 1 65  GLN 65  86  86  GLN GLN A . n 
A 1 66  SER 66  87  87  SER SER A . n 
A 1 67  LEU 67  88  88  LEU LEU A . n 
A 1 68  GLU 68  89  89  GLU GLU A . n 
A 1 69  LEU 69  90  90  LEU LEU A . n 
A 1 70  MET 70  91  91  MET MET A . n 
A 1 71  ARG 71  92  92  ARG ARG A . n 
A 1 72  ASN 72  93  93  ASN ASN A . n 
A 1 73  ASN 73  94  94  ASN ASN A . n 
A 1 74  VAL 74  95  95  VAL VAL A . n 
A 1 75  LYS 75  96  96  LYS LYS A . n 
A 1 76  ASP 76  97  97  ASP ASP A . n 
A 1 77  GLY 77  98  98  GLY GLY A . n 
A 1 78  THR 78  99  99  THR THR A . n 
A 1 79  PRO 79  100 100 PRO PRO A . n 
A 1 80  ASN 80  101 101 ASN ASN A . n 
A 1 81  GLU 81  102 102 GLU GLU A . n 
A 1 82  ASN 82  103 103 ASN ASN A . n 
A 1 83  ILE 83  104 104 ILE ILE A . n 
A 1 84  PHE 84  105 105 PHE PHE A . n 
A 1 85  GLY 85  106 106 GLY GLY A . n 
A 1 86  ALA 86  107 107 ALA ALA A . n 
A 1 87  ILE 87  108 108 ILE ILE A . n 
A 1 88  VAL 88  109 109 VAL VAL A . n 
A 1 89  ALA 89  110 110 ALA ALA A . n 
A 1 90  GLY 90  111 111 GLY GLY A . n 
A 1 91  ALA 91  112 112 ALA ALA A . n 
A 1 92  ALA 92  113 113 ALA ALA A . n 
A 1 93  LEU 93  114 114 LEU LEU A . n 
A 1 94  GLY 94  115 115 GLY GLY A . n 
A 1 95  ILE 95  116 116 ILE ILE A . n 
A 1 96  ALA 96  117 117 ALA ALA A . n 
A 1 97  THR 97  118 118 THR THR A . n 
A 1 98  ALA 98  119 119 ALA ALA A . n 
A 1 99  ALA 99  120 120 ALA ALA A . n 
A 1 100 GLN 100 121 121 GLN GLN A . n 
A 1 101 VAL 101 122 122 VAL VAL A . n 
A 1 102 THR 102 123 123 THR THR A . n 
A 1 103 SER 103 124 124 SER SER A . n 
A 1 104 VAL 104 125 125 VAL VAL A . n 
A 1 105 VAL 105 126 126 VAL VAL A . n 
A 1 106 ALA 106 127 127 ALA ALA A . n 
A 1 107 LEU 107 128 128 LEU LEU A . n 
A 1 108 HIS 108 129 129 HIS HIS A . n 
A 1 109 LYS 109 130 130 LYS LYS A . n 
A 1 110 SER 110 131 131 SER SER A . n 
A 1 111 ASN 111 132 132 ASN ASN A . n 
A 1 112 GLN 112 133 133 GLN GLN A . n 
A 1 113 ASN 113 134 134 ASN ASN A . n 
A 1 114 ALA 114 135 135 ALA ALA A . n 
A 1 115 ALA 115 136 136 ALA ALA A . n 
A 1 116 LYS 116 137 137 LYS LYS A . n 
A 1 117 ILE 117 138 138 ILE ILE A . n 
A 1 118 ASN 118 139 139 ASN ASN A . n 
A 1 119 SER 119 140 140 SER SER A . n 
A 1 120 LEU 120 141 141 LEU LEU A . n 
A 1 121 ARG 121 142 142 ARG ARG A . n 
A 1 122 ASP 122 143 143 ASP ASP A . n 
A 1 123 SER 123 144 144 SER SER A . n 
A 1 124 ILE 124 145 145 ILE ILE A . n 
A 1 125 THR 125 146 146 THR THR A . n 
A 1 126 LYS 126 147 147 LYS LYS A . n 
A 1 127 THR 127 148 148 THR THR A . n 
A 1 128 ASN 128 149 149 ASN ASN A . n 
A 1 129 GLN 129 150 150 GLN GLN A . n 
A 1 130 ALA 130 151 151 ALA ALA A . n 
A 1 131 VAL 131 152 152 VAL VAL A . n 
A 1 132 GLU 132 153 153 GLU GLU A . n 
A 1 133 GLN 133 154 154 GLN GLN A . n 
A 1 134 LEU 134 155 155 LEU LEU A . n 
A 1 135 SER 135 156 156 SER SER A . n 
A 1 136 LEU 136 157 157 LEU LEU A . n 
A 1 137 GLY 137 158 158 GLY GLY A . n 
A 1 138 VAL 138 159 159 VAL VAL A . n 
A 1 139 GLN 139 160 160 GLN GLN A . n 
A 1 140 GLU 140 161 161 GLU GLU A . n 
A 1 141 THR 141 162 162 THR THR A . n 
A 1 142 VAL 142 163 163 VAL VAL A . n 
A 1 143 SER 143 164 164 SER SER A . n 
A 1 144 VAL 144 165 165 VAL VAL A . n 
A 1 145 LEU 145 166 166 LEU LEU A . n 
A 1 146 MET 146 167 167 MET MET A . n 
A 1 147 GLY 147 168 168 GLY GLY A . n 
A 1 148 LEU 148 169 169 LEU LEU A . n 
A 1 149 GLN 149 170 170 GLN GLN A . n 
A 1 150 ASP 150 171 171 ASP ASP A . n 
A 1 151 GLN 151 172 172 GLN GLN A . n 
A 1 152 ILE 152 173 173 ILE ILE A . n 
A 1 153 ASN 153 174 174 ASN ASN A . n 
A 1 154 THR 154 175 175 THR THR A . n 
A 1 155 ASN 155 176 176 ASN ASN A . n 
A 1 156 LEU 156 177 177 LEU LEU A . n 
A 1 157 VAL 157 178 178 VAL VAL A . n 
A 1 158 PRO 158 179 179 PRO PRO A . n 
A 1 159 LYS 159 180 180 LYS LYS A . n 
A 1 160 ILE 160 181 181 ILE ILE A . n 
A 1 161 ASN 161 182 182 ASN ASN A . n 
A 1 162 ILE 162 183 183 ILE ILE A . n 
A 1 163 LEU 163 184 184 LEU LEU A . n 
A 1 164 SER 164 185 185 SER SER A . n 
A 1 165 CYS 165 186 186 CYS CYS A . n 
A 1 166 LYS 166 187 187 LYS LYS A . n 
A 1 167 GLN 167 188 188 GLN GLN A . n 
A 1 168 LEU 168 189 189 LEU LEU A . n 
A 1 169 SER 169 190 190 SER SER A . n 
A 1 170 ASN 170 191 191 ASN ASN A . n 
A 1 171 THR 171 192 192 THR THR A . n 
A 1 172 LEU 172 193 193 LEU LEU A . n 
A 1 173 ASN 173 194 194 ASN ASN A . n 
A 1 174 ILE 174 195 195 ILE ILE A . n 
A 1 175 MET 175 196 196 MET MET A . n 
A 1 176 LEU 176 197 197 LEU LEU A . n 
A 1 177 LEU 177 198 198 LEU LEU A . n 
A 1 178 GLN 178 199 199 GLN GLN A . n 
A 1 179 TYR 179 200 200 TYR TYR A . n 
A 1 180 TYR 180 201 201 TYR TYR A . n 
A 1 181 SER 181 202 202 SER SER A . n 
A 1 182 GLN 182 203 203 GLN GLN A . n 
A 1 183 ILE 183 204 204 ILE ILE A . n 
A 1 184 LEU 184 205 205 LEU LEU A . n 
A 1 185 THR 185 206 206 THR THR A . n 
A 1 186 VAL 186 207 207 VAL VAL A . n 
A 1 187 PHE 187 208 208 PHE PHE A . n 
A 1 188 GLY 188 209 209 GLY GLY A . n 
A 1 189 PRO 189 210 210 PRO PRO A . n 
A 1 190 ASN 190 211 211 ASN ASN A . n 
A 1 191 LEU 191 212 212 LEU LEU A . n 
A 1 192 ARG 192 213 213 ARG ARG A . n 
A 1 193 ASP 193 214 214 ASP ASP A . n 
A 1 194 PRO 194 215 215 PRO PRO A . n 
A 1 195 ALA 195 216 216 ALA ALA A . n 
A 1 196 THR 196 217 217 THR THR A . n 
A 1 197 VAL 197 218 218 VAL VAL A . n 
A 1 198 PRO 198 219 219 PRO PRO A . n 
A 1 199 VAL 199 220 220 VAL VAL A . n 
A 1 200 SER 200 221 221 SER SER A . n 
A 1 201 ILE 201 222 222 ILE ILE A . n 
A 1 202 GLN 202 223 223 GLN GLN A . n 
A 1 203 ALA 203 224 224 ALA ALA A . n 
A 1 204 LEU 204 225 225 LEU LEU A . n 
A 1 205 SER 205 226 226 SER SER A . n 
A 1 206 GLN 206 227 227 GLN GLN A . n 
A 1 207 LEU 207 228 228 LEU LEU A . n 
A 1 208 PHE 208 229 229 PHE PHE A . n 
A 1 209 GLU 209 230 230 GLU GLU A . n 
A 1 210 GLY 210 231 231 GLY GLY A . n 
A 1 211 ASN 211 232 232 ASN ASN A . n 
A 1 212 LEU 212 233 233 LEU LEU A . n 
A 1 213 GLU 213 234 234 GLU GLU A . n 
A 1 214 LEU 214 235 235 LEU LEU A . n 
A 1 215 LEU 215 236 236 LEU LEU A . n 
A 1 216 THR 216 237 237 THR THR A . n 
A 1 217 SER 217 238 238 SER SER A . n 
A 1 218 SER 218 239 239 SER SER A . n 
A 1 219 LEU 219 240 240 LEU LEU A . n 
A 1 220 GLY 220 241 241 GLY GLY A . n 
A 1 221 ILE 221 242 242 ILE ILE A . n 
A 1 222 SER 222 243 243 SER SER A . n 
A 1 223 SER 223 244 244 SER SER A . n 
A 1 224 THR 224 245 245 THR THR A . n 
A 1 225 ASP 225 246 246 ASP ASP A . n 
A 1 226 PHE 226 247 247 PHE PHE A . n 
A 1 227 ASN 227 248 248 ASN ASN A . n 
A 1 228 ASP 228 249 249 ASP ASP A . n 
A 1 229 LEU 229 250 250 LEU LEU A . n 
A 1 230 LEU 230 251 251 LEU LEU A . n 
A 1 231 THR 231 252 252 THR THR A . n 
A 1 232 GLY 232 253 253 GLY GLY A . n 
A 1 233 LYS 233 254 254 LYS LYS A . n 
A 1 234 LEU 234 255 255 LEU LEU A . n 
A 1 235 ILE 235 256 256 ILE ILE A . n 
A 1 236 THR 236 257 257 THR THR A . n 
A 1 237 GLY 237 258 258 GLY GLY A . n 
A 1 238 SER 238 259 259 SER SER A . n 
A 1 239 ILE 239 260 260 ILE ILE A . n 
A 1 240 ILE 240 261 261 ILE ILE A . n 
A 1 241 TRP 241 262 262 TRP TRP A . n 
A 1 242 ALA 242 263 263 ALA ALA A . n 
A 1 243 ASP 243 264 264 ASP ASP A . n 
A 1 244 THR 244 265 265 THR THR A . n 
A 1 245 GLN 245 266 266 GLN GLN A . n 
A 1 246 GLY 246 267 267 GLY GLY A . n 
A 1 247 HIS 247 268 268 HIS HIS A . n 
A 1 248 TYR 248 269 269 TYR TYR A . n 
A 1 249 LEU 249 270 270 LEU LEU A . n 
A 1 250 ILE 250 271 271 ILE ILE A . n 
A 1 251 LEU 251 272 272 LEU LEU A . n 
A 1 252 ARG 252 273 273 ARG ARG A . n 
A 1 253 VAL 253 274 274 VAL VAL A . n 
A 1 254 ASN 254 275 275 ASN ASN A . n 
A 1 255 ILE 255 276 276 ILE ILE A . n 
A 1 256 PRO 256 277 277 PRO PRO A . n 
A 1 257 ASP 257 278 278 ASP ASP A . n 
A 1 258 LEU 258 279 279 LEU LEU A . n 
A 1 259 ILE 259 280 280 ILE ILE A . n 
A 1 260 GLU 260 281 281 GLU GLU A . n 
A 1 261 VAL 261 282 282 VAL VAL A . n 
A 1 262 PRO 262 283 283 PRO PRO A . n 
A 1 263 GLY 263 284 284 GLY GLY A . n 
A 1 264 ALA 264 285 285 ALA ALA A . n 
A 1 265 VAL 265 286 286 VAL VAL A . n 
A 1 266 ILE 266 287 287 ILE ILE A . n 
A 1 267 GLN 267 288 288 GLN GLN A . n 
A 1 268 GLU 268 289 289 GLU GLU A . n 
A 1 269 PHE 269 290 290 PHE PHE A . n 
A 1 270 ILE 270 291 291 ILE ILE A . n 
A 1 271 LYS 271 292 292 LYS LYS A . n 
A 1 272 ILE 272 293 293 ILE ILE A . n 
A 1 273 GLY 273 294 294 GLY GLY A . n 
A 1 274 TYR 274 295 295 TYR TYR A . n 
A 1 275 ASN 275 296 296 ASN ASN A . n 
A 1 276 PHE 276 297 297 PHE PHE A . n 
A 1 277 GLY 277 298 298 GLY GLY A . n 
A 1 278 GLY 278 299 299 GLY GLY A . n 
A 1 279 SER 279 300 300 SER SER A . n 
A 1 280 LEU 280 301 301 LEU LEU A . n 
A 1 281 TRP 281 302 302 TRP TRP A . n 
A 1 282 MET 282 303 303 MET MET A . n 
A 1 283 PRO 283 304 304 PRO PRO A . n 
A 1 284 THR 284 305 305 THR THR A . n 
A 1 285 ILE 285 306 306 ILE ILE A . n 
A 1 286 PRO 286 307 307 PRO PRO A . n 
A 1 287 ASN 287 308 308 ASN ASN A . n 
A 1 288 LYS 288 309 309 LYS LYS A . n 
A 1 289 ILE 289 310 310 ILE ILE A . n 
A 1 290 ILE 290 311 311 ILE ILE A . n 
A 1 291 ILE 291 312 312 ILE ILE A . n 
A 1 292 ARG 292 313 313 ARG ARG A . n 
A 1 293 GLY 293 314 314 GLY GLY A . n 
A 1 294 TYR 294 315 315 TYR TYR A . n 
A 1 295 HIS 295 316 316 HIS HIS A . n 
A 1 296 LEU 296 317 317 LEU LEU A . n 
A 1 297 SER 297 318 318 SER SER A . n 
A 1 298 LEU 298 319 319 LEU LEU A . n 
A 1 299 ILE 299 320 320 ILE ILE A . n 
A 1 300 ASP 300 321 321 ASP ASP A . n 
A 1 301 SER 301 322 322 SER SER A . n 
A 1 302 THR 302 323 323 THR THR A . n 
A 1 303 ASN 303 324 324 ASN ASN A . n 
A 1 304 CYS 304 325 325 CYS CYS A . n 
A 1 305 ILE 305 326 326 ILE ILE A . n 
A 1 306 ILE 306 327 327 ILE ILE A . n 
A 1 307 THR 307 328 328 THR THR A . n 
A 1 308 ASP 308 329 329 ASP ASP A . n 
A 1 309 ASN 309 330 330 ASN ASN A . n 
A 1 310 SER 310 331 331 SER SER A . n 
A 1 311 TYR 311 332 332 TYR TYR A . n 
A 1 312 VAL 312 333 333 VAL VAL A . n 
A 1 313 CYS 313 334 334 CYS CYS A . n 
A 1 314 ASP 314 335 335 ASP ASP A . n 
A 1 315 ARG 315 336 336 ARG ARG A . n 
A 1 316 ASP 316 337 337 ASP ASP A . n 
A 1 317 TYR 317 338 338 TYR TYR A . n 
A 1 318 SER 318 339 339 SER SER A . n 
A 1 319 LEU 319 340 340 LEU LEU A . n 
A 1 320 PRO 320 341 341 PRO PRO A . n 
A 1 321 MET 321 342 342 MET MET A . n 
A 1 322 ASN 322 343 343 ASN ASN A . n 
A 1 323 PRO 323 344 344 PRO PRO A . n 
A 1 324 ILE 324 345 345 ILE ILE A . n 
A 1 325 LEU 325 346 346 LEU LEU A . n 
A 1 326 ARG 326 347 347 ARG ARG A . n 
A 1 327 GLU 327 348 348 GLU GLU A . n 
A 1 328 CYS 328 349 349 CYS CYS A . n 
A 1 329 PHE 329 350 350 PHE PHE A . n 
A 1 330 GLU 330 351 351 GLU GLU A . n 
A 1 331 GLY 331 352 352 GLY GLY A . n 
A 1 332 ASN 332 353 353 ASN ASN A . n 
A 1 333 THR 333 354 354 THR THR A . n 
A 1 334 SER 334 355 355 SER SER A . n 
A 1 335 SER 335 356 356 SER SER A . n 
A 1 336 CYS 336 357 357 CYS CYS A . n 
A 1 337 GLY 337 358 358 GLY GLY A . n 
A 1 338 ARG 338 359 359 ARG ARG A . n 
A 1 339 GLU 339 360 360 GLU GLU A . n 
A 1 340 MET 340 361 361 MET MET A . n 
A 1 341 VAL 341 362 362 VAL VAL A . n 
A 1 342 LEU 342 363 363 LEU LEU A . n 
A 1 343 ASN 343 364 364 ASN ASN A . n 
A 1 344 SER 344 365 365 SER SER A . n 
A 1 345 TYR 345 366 366 TYR TYR A . n 
A 1 346 ILE 346 367 367 ILE ILE A . n 
A 1 347 PRO 347 368 368 PRO PRO A . n 
A 1 348 LEU 348 369 369 LEU LEU A . n 
A 1 349 TYR 349 370 370 TYR TYR A . n 
A 1 350 ALA 350 371 371 ALA ALA A . n 
A 1 351 LEU 351 372 372 LEU LEU A . n 
A 1 352 SER 352 373 373 SER SER A . n 
A 1 353 GLU 353 374 374 GLU GLU A . n 
A 1 354 GLY 354 375 375 GLY GLY A . n 
A 1 355 VAL 355 376 376 VAL VAL A . n 
A 1 356 ILE 356 377 377 ILE ILE A . n 
A 1 357 TYR 357 378 378 TYR TYR A . n 
A 1 358 ALA 358 379 379 ALA ALA A . n 
A 1 359 ASN 359 380 380 ASN ASN A . n 
A 1 360 CYS 360 381 381 CYS CYS A . n 
A 1 361 LEU 361 382 382 LEU LEU A . n 
A 1 362 ALA 362 383 383 ALA ALA A . n 
A 1 363 THR 363 384 384 THR THR A . n 
A 1 364 SER 364 385 385 SER SER A . n 
A 1 365 CYS 365 386 386 CYS CYS A . n 
A 1 366 LYS 366 387 387 LYS LYS A . n 
A 1 367 CYS 367 388 388 CYS CYS A . n 
A 1 368 ALA 368 389 389 ALA ALA A . n 
A 1 369 THR 369 390 390 THR THR A . n 
A 1 370 THR 370 391 391 THR THR A . n 
A 1 371 ASN 371 392 392 ASN ASN A . n 
A 1 372 LYS 372 393 393 LYS LYS A . n 
A 1 373 PRO 373 394 394 PRO PRO A . n 
A 1 374 ILE 374 395 395 ILE ILE A . n 
A 1 375 VAL 375 396 396 VAL VAL A . n 
A 1 376 GLN 376 397 397 GLN GLN A . n 
A 1 377 SER 377 398 398 SER SER A . n 
A 1 378 THR 378 399 399 THR THR A . n 
A 1 379 SER 379 400 400 SER SER A . n 
A 1 380 THR 380 401 401 THR THR A . n 
A 1 381 VAL 381 402 402 VAL VAL A . n 
A 1 382 ILE 382 403 403 ILE ILE A . n 
A 1 383 THR 383 404 404 THR THR A . n 
A 1 384 MET 384 405 405 MET MET A . n 
A 1 385 ILE 385 406 406 ILE ILE A . n 
A 1 386 ASP 386 407 407 ASP ASP A . n 
A 1 387 ASN 387 408 408 ASN ASN A . n 
A 1 388 SER 388 409 409 SER SER A . n 
A 1 389 LYS 389 410 410 LYS LYS A . n 
A 1 390 CYS 390 411 411 CYS CYS A . n 
A 1 391 PRO 391 412 412 PRO PRO A . n 
A 1 392 VAL 392 413 413 VAL VAL A . n 
A 1 393 VAL 393 414 414 VAL VAL A . n 
A 1 394 GLU 394 415 415 GLU GLU A . n 
A 1 395 VAL 395 416 416 VAL VAL A . n 
A 1 396 GLY 396 417 417 GLY GLY A . n 
A 1 397 LYS 397 418 418 LYS LYS A . n 
A 1 398 GLN 398 419 419 GLN GLN A . n 
A 1 399 MET 399 420 420 MET MET A . n 
A 1 400 ILE 400 421 421 ILE ILE A . n 
A 1 401 SER 401 422 422 SER SER A . n 
A 1 402 VAL 402 423 423 VAL VAL A . n 
A 1 403 GLY 403 424 424 GLY GLY A . n 
A 1 404 SER 404 425 425 SER SER A . n 
A 1 405 TYR 405 426 426 TYR TYR A . n 
A 1 406 LEU 406 427 427 LEU LEU A . n 
A 1 407 GLY 407 428 428 GLY GLY A . n 
A 1 408 GLN 408 429 429 GLN GLN A . n 
A 1 409 VAL 409 430 430 VAL VAL A . n 
A 1 410 SER 410 431 431 SER SER A . n 
A 1 411 PRO 411 432 432 PRO PRO A . n 
A 1 412 ASN 412 433 433 ASN ASN A . n 
A 1 413 ASN 413 434 434 ASN ASN A . n 
A 1 414 LEU 414 435 435 LEU LEU A . n 
A 1 415 THR 415 436 436 THR THR A . n 
A 1 416 ILE 416 437 437 ILE ILE A . n 
A 1 417 GLU 417 438 438 GLU GLU A . n 
A 1 418 ILE 418 439 439 ILE ILE A . n 
A 1 419 GLY 419 440 440 GLY GLY A . n 
A 1 420 PRO 420 441 441 PRO PRO A . n 
A 1 421 PRO 421 442 442 PRO PRO A . n 
A 1 422 VAL 422 443 443 VAL VAL A . n 
A 1 423 TYR 423 444 444 TYR TYR A . n 
A 1 424 THR 424 445 445 THR THR A . n 
A 1 425 GLU 425 446 446 GLU GLU A . n 
A 1 426 PRO 426 447 447 PRO PRO A . n 
A 1 427 VAL 427 448 448 VAL VAL A . n 
A 1 428 ASP 428 449 449 ASP ASP A . n 
A 1 429 ILE 429 450 450 ILE ILE A . n 
A 1 430 THR 430 451 451 THR THR A . n 
A 1 431 ASN 431 452 452 ASN ASN A . n 
A 1 432 GLN 432 453 453 GLN GLN A . n 
A 1 433 LEU 433 454 454 LEU LEU A . n 
A 1 434 GLY 434 455 455 GLY GLY A . n 
A 1 435 ASN 435 456 456 ASN ASN A . n 
A 1 436 ILE 436 457 457 ILE ILE A . n 
A 1 437 ASN 437 458 458 ASN ASN A . n 
A 1 438 GLU 438 459 459 GLU GLU A . n 
A 1 439 THR 439 460 460 THR THR A . n 
A 1 440 LEU 440 461 461 LEU LEU A . n 
A 1 441 SER 441 462 462 SER SER A . n 
A 1 442 LYS 442 463 463 LYS LYS A . n 
A 1 443 THR 443 464 464 THR THR A . n 
A 1 444 LEU 444 465 465 LEU LEU A . n 
A 1 445 ASP 445 466 466 ASP ASP A . n 
A 1 446 LEU 446 467 467 LEU LEU A . n 
A 1 447 ILE 447 468 468 ILE ILE A . n 
A 1 448 LYS 448 469 469 LYS LYS A . n 
A 1 449 GLN 449 470 470 GLN GLN A . n 
A 1 450 SER 450 471 471 SER SER A . n 
A 1 451 ASN 451 472 472 ASN ASN A . n 
A 1 452 SER 452 473 473 SER SER A . n 
A 1 453 ILE 453 474 474 ILE ILE A . n 
A 1 454 LEU 454 475 475 LEU LEU A . n 
A 1 455 ASP 455 476 476 ASP ASP A . n 
A 1 456 MET 456 477 477 MET MET A . n 
A 1 457 ILE 457 478 478 ILE ILE A . n 
A 1 458 THR 458 479 479 THR THR A . n 
A 1 459 GLY 459 480 480 GLY GLY A . n 
A 1 460 GLY 460 481 481 GLY GLY A . n 
A 1 461 LEU 461 482 482 LEU LEU A . n 
A 1 462 GLY 462 483 ?   ?   ?   A . n 
A 1 463 SER 463 484 ?   ?   ?   A . n 
A 1 464 GLY 464 485 ?   ?   ?   A . n 
A 1 465 TYR 465 486 ?   ?   ?   A . n 
A 1 466 ILE 466 487 ?   ?   ?   A . n 
A 1 467 PRO 467 488 ?   ?   ?   A . n 
A 1 468 GLU 468 489 ?   ?   ?   A . n 
A 1 469 ALA 469 490 ?   ?   ?   A . n 
A 1 470 PRO 470 491 ?   ?   ?   A . n 
A 1 471 ARG 471 492 ?   ?   ?   A . n 
A 1 472 ASP 472 493 ?   ?   ?   A . n 
A 1 473 GLY 473 494 ?   ?   ?   A . n 
A 1 474 GLN 474 495 ?   ?   ?   A . n 
A 1 475 ALA 475 496 ?   ?   ?   A . n 
A 1 476 TYR 476 497 ?   ?   ?   A . n 
A 1 477 VAL 477 498 ?   ?   ?   A . n 
A 1 478 ARG 478 499 ?   ?   ?   A . n 
A 1 479 LYS 479 500 ?   ?   ?   A . n 
A 1 480 ASP 480 501 ?   ?   ?   A . n 
A 1 481 GLY 481 502 ?   ?   ?   A . n 
A 1 482 GLU 482 503 ?   ?   ?   A . n 
A 1 483 TRP 483 504 ?   ?   ?   A . n 
A 1 484 VAL 484 505 ?   ?   ?   A . n 
A 1 485 LEU 485 506 ?   ?   ?   A . n 
A 1 486 LEU 486 507 ?   ?   ?   A . n 
A 1 487 SER 487 508 ?   ?   ?   A . n 
A 1 488 THR 488 509 ?   ?   ?   A . n 
A 1 489 PHE 489 510 ?   ?   ?   A . n 
A 1 490 LEU 490 511 ?   ?   ?   A . n 
A 1 491 GLY 491 512 ?   ?   ?   A . n 
A 1 492 ARG 492 513 ?   ?   ?   A . n 
A 1 493 SER 493 514 ?   ?   ?   A . n 
A 1 494 LEU 494 515 ?   ?   ?   A . n 
A 1 495 GLU 495 516 ?   ?   ?   A . n 
A 1 496 VAL 496 517 ?   ?   ?   A . n 
A 1 497 LEU 497 518 ?   ?   ?   A . n 
A 1 498 PHE 498 519 ?   ?   ?   A . n 
A 1 499 GLN 499 520 ?   ?   ?   A . n 
A 1 500 GLY 500 521 ?   ?   ?   A . n 
A 1 501 PRO 501 522 ?   ?   ?   A . n 
A 1 502 GLY 502 523 ?   ?   ?   A . n 
A 1 503 HIS 503 524 ?   ?   ?   A . n 
A 1 504 HIS 504 525 ?   ?   ?   A . n 
A 1 505 HIS 505 526 ?   ?   ?   A . n 
A 1 506 HIS 506 527 ?   ?   ?   A . n 
A 1 507 HIS 507 528 ?   ?   ?   A . n 
A 1 508 HIS 508 529 ?   ?   ?   A . n 
A 1 509 HIS 509 530 ?   ?   ?   A . n 
A 1 510 HIS 510 531 ?   ?   ?   A . n 
A 1 511 SER 511 532 ?   ?   ?   A . n 
A 1 512 ALA 512 533 ?   ?   ?   A . n 
A 1 513 TRP 513 534 ?   ?   ?   A . n 
A 1 514 SER 514 535 ?   ?   ?   A . n 
A 1 515 HIS 515 536 ?   ?   ?   A . n 
A 1 516 PRO 516 537 ?   ?   ?   A . n 
A 1 517 GLN 517 538 ?   ?   ?   A . n 
A 1 518 PHE 518 539 ?   ?   ?   A . n 
A 1 519 GLU 519 540 ?   ?   ?   A . n 
A 1 520 LYS 520 541 ?   ?   ?   A . n 
A 1 521 GLY 521 542 ?   ?   ?   A . n 
A 1 522 GLY 522 543 ?   ?   ?   A . n 
A 1 523 GLY 523 544 ?   ?   ?   A . n 
A 1 524 SER 524 545 ?   ?   ?   A . n 
A 1 525 GLY 525 546 ?   ?   ?   A . n 
A 1 526 GLY 526 547 ?   ?   ?   A . n 
A 1 527 GLY 527 548 ?   ?   ?   A . n 
A 1 528 GLY 528 549 ?   ?   ?   A . n 
A 1 529 SER 529 550 ?   ?   ?   A . n 
A 1 530 GLY 530 551 ?   ?   ?   A . n 
A 1 531 GLY 531 552 ?   ?   ?   A . n 
A 1 532 SER 532 553 ?   ?   ?   A . n 
A 1 533 ALA 533 554 ?   ?   ?   A . n 
A 1 534 TRP 534 555 ?   ?   ?   A . n 
A 1 535 SER 535 556 ?   ?   ?   A . n 
A 1 536 HIS 536 557 ?   ?   ?   A . n 
A 1 537 PRO 537 558 ?   ?   ?   A . n 
A 1 538 GLN 538 559 ?   ?   ?   A . n 
A 1 539 PHE 539 560 ?   ?   ?   A . n 
A 1 540 GLU 540 561 ?   ?   ?   A . n 
A 1 541 LYS 541 562 ?   ?   ?   A . n 
B 1 1   VAL 1   22  22  VAL VAL B . n 
B 1 2   ASP 2   23  23  ASP ASP B . n 
B 1 3   PHE 3   24  24  PHE PHE B . n 
B 1 4   GLU 4   25  25  GLU GLU B . n 
B 1 5   ARG 5   26  26  ARG ARG B . n 
B 1 6   LEU 6   27  27  LEU LEU B . n 
B 1 7   ALA 7   28  28  ALA ALA B . n 
B 1 8   SER 8   29  29  SER SER B . n 
B 1 9   ILE 9   30  30  ILE ILE B . n 
B 1 10  GLY 10  31  31  GLY GLY B . n 
B 1 11  GLY 11  32  32  GLY GLY B . n 
B 1 12  ILE 12  33  33  ILE ILE B . n 
B 1 13  LYS 13  34  34  LYS LYS B . n 
B 1 14  GLY 14  35  35  GLY GLY B . n 
B 1 15  HIS 15  36  36  HIS HIS B . n 
B 1 16  SER 16  37  37  SER SER B . n 
B 1 17  LYS 17  38  38  LYS LYS B . n 
B 1 18  LEU 18  39  39  LEU LEU B . n 
B 1 19  TYR 19  40  40  TYR TYR B . n 
B 1 20  LYS 20  41  41  LYS LYS B . n 
B 1 21  ILE 21  42  42  ILE ILE B . n 
B 1 22  LYS 22  43  43  LYS LYS B . n 
B 1 23  GLY 23  44  44  GLY GLY B . n 
B 1 24  HIS 24  45  45  HIS HIS B . n 
B 1 25  PRO 25  46  46  PRO PRO B . n 
B 1 26  THR 26  47  47  THR THR B . n 
B 1 27  THR 27  48  48  THR THR B . n 
B 1 28  LYS 28  49  49  LYS LYS B . n 
B 1 29  ASP 29  50  50  ASP ASP B . n 
B 1 30  ILE 30  51  51  ILE ILE B . n 
B 1 31  VAL 31  52  52  VAL VAL B . n 
B 1 32  ILE 32  53  53  ILE ILE B . n 
B 1 33  LYS 33  54  54  LYS LYS B . n 
B 1 34  LEU 34  55  55  LEU LEU B . n 
B 1 35  VAL 35  56  56  VAL VAL B . n 
B 1 36  PRO 36  57  57  PRO PRO B . n 
B 1 37  ASN 37  58  58  ASN ASN B . n 
B 1 38  LEU 38  59  59  LEU LEU B . n 
B 1 39  ASN 39  60  60  ASN ASN B . n 
B 1 40  ASN 40  61  61  ASN ASN B . n 
B 1 41  LEU 41  62  62  LEU LEU B . n 
B 1 42  THR 42  63  63  THR THR B . n 
B 1 43  VAL 43  64  64  VAL VAL B . n 
B 1 44  CYS 44  65  65  CYS CYS B . n 
B 1 45  SER 45  66  66  SER SER B . n 
B 1 46  GLU 46  67  67  GLU GLU B . n 
B 1 47  MET 47  68  68  MET MET B . n 
B 1 48  SER 48  69  69  SER SER B . n 
B 1 49  ILE 49  70  70  ILE ILE B . n 
B 1 50  ASP 50  71  71  ASP ASP B . n 
B 1 51  GLY 51  72  72  GLY GLY B . n 
B 1 52  TYR 52  73  73  TYR TYR B . n 
B 1 53  LEU 53  74  74  LEU LEU B . n 
B 1 54  ASN 54  75  75  ASN ASN B . n 
B 1 55  LEU 55  76  76  LEU LEU B . n 
B 1 56  ILE 56  77  77  ILE ILE B . n 
B 1 57  ASN 57  78  78  ASN ASN B . n 
B 1 58  ALA 58  79  79  ALA ALA B . n 
B 1 59  VAL 59  80  80  VAL VAL B . n 
B 1 60  ILE 60  81  81  ILE ILE B . n 
B 1 61  ILE 61  82  82  ILE ILE B . n 
B 1 62  PRO 62  83  83  PRO PRO B . n 
B 1 63  ILE 63  84  84  ILE ILE B . n 
B 1 64  SER 64  85  85  SER SER B . n 
B 1 65  GLN 65  86  86  GLN GLN B . n 
B 1 66  SER 66  87  87  SER SER B . n 
B 1 67  LEU 67  88  88  LEU LEU B . n 
B 1 68  GLU 68  89  89  GLU GLU B . n 
B 1 69  LEU 69  90  90  LEU LEU B . n 
B 1 70  MET 70  91  91  MET MET B . n 
B 1 71  ARG 71  92  92  ARG ARG B . n 
B 1 72  ASN 72  93  93  ASN ASN B . n 
B 1 73  ASN 73  94  94  ASN ASN B . n 
B 1 74  VAL 74  95  95  VAL VAL B . n 
B 1 75  LYS 75  96  96  LYS LYS B . n 
B 1 76  ASP 76  97  97  ASP ASP B . n 
B 1 77  GLY 77  98  98  GLY GLY B . n 
B 1 78  THR 78  99  99  THR THR B . n 
B 1 79  PRO 79  100 100 PRO PRO B . n 
B 1 80  ASN 80  101 101 ASN ASN B . n 
B 1 81  GLU 81  102 102 GLU GLU B . n 
B 1 82  ASN 82  103 103 ASN ASN B . n 
B 1 83  ILE 83  104 104 ILE ILE B . n 
B 1 84  PHE 84  105 105 PHE PHE B . n 
B 1 85  GLY 85  106 106 GLY GLY B . n 
B 1 86  ALA 86  107 107 ALA ALA B . n 
B 1 87  ILE 87  108 108 ILE ILE B . n 
B 1 88  VAL 88  109 109 VAL VAL B . n 
B 1 89  ALA 89  110 110 ALA ALA B . n 
B 1 90  GLY 90  111 111 GLY GLY B . n 
B 1 91  ALA 91  112 112 ALA ALA B . n 
B 1 92  ALA 92  113 113 ALA ALA B . n 
B 1 93  LEU 93  114 114 LEU LEU B . n 
B 1 94  GLY 94  115 115 GLY GLY B . n 
B 1 95  ILE 95  116 116 ILE ILE B . n 
B 1 96  ALA 96  117 117 ALA ALA B . n 
B 1 97  THR 97  118 118 THR THR B . n 
B 1 98  ALA 98  119 119 ALA ALA B . n 
B 1 99  ALA 99  120 120 ALA ALA B . n 
B 1 100 GLN 100 121 121 GLN GLN B . n 
B 1 101 VAL 101 122 122 VAL VAL B . n 
B 1 102 THR 102 123 123 THR THR B . n 
B 1 103 SER 103 124 124 SER SER B . n 
B 1 104 VAL 104 125 125 VAL VAL B . n 
B 1 105 VAL 105 126 126 VAL VAL B . n 
B 1 106 ALA 106 127 127 ALA ALA B . n 
B 1 107 LEU 107 128 128 LEU LEU B . n 
B 1 108 HIS 108 129 129 HIS HIS B . n 
B 1 109 LYS 109 130 130 LYS LYS B . n 
B 1 110 SER 110 131 131 SER SER B . n 
B 1 111 ASN 111 132 132 ASN ASN B . n 
B 1 112 GLN 112 133 133 GLN GLN B . n 
B 1 113 ASN 113 134 134 ASN ASN B . n 
B 1 114 ALA 114 135 135 ALA ALA B . n 
B 1 115 ALA 115 136 136 ALA ALA B . n 
B 1 116 LYS 116 137 137 LYS LYS B . n 
B 1 117 ILE 117 138 138 ILE ILE B . n 
B 1 118 ASN 118 139 139 ASN ASN B . n 
B 1 119 SER 119 140 140 SER SER B . n 
B 1 120 LEU 120 141 141 LEU LEU B . n 
B 1 121 ARG 121 142 142 ARG ARG B . n 
B 1 122 ASP 122 143 143 ASP ASP B . n 
B 1 123 SER 123 144 144 SER SER B . n 
B 1 124 ILE 124 145 145 ILE ILE B . n 
B 1 125 THR 125 146 146 THR THR B . n 
B 1 126 LYS 126 147 147 LYS LYS B . n 
B 1 127 THR 127 148 148 THR THR B . n 
B 1 128 ASN 128 149 149 ASN ASN B . n 
B 1 129 GLN 129 150 150 GLN GLN B . n 
B 1 130 ALA 130 151 151 ALA ALA B . n 
B 1 131 VAL 131 152 152 VAL VAL B . n 
B 1 132 GLU 132 153 153 GLU GLU B . n 
B 1 133 GLN 133 154 154 GLN GLN B . n 
B 1 134 LEU 134 155 155 LEU LEU B . n 
B 1 135 SER 135 156 156 SER SER B . n 
B 1 136 LEU 136 157 157 LEU LEU B . n 
B 1 137 GLY 137 158 158 GLY GLY B . n 
B 1 138 VAL 138 159 159 VAL VAL B . n 
B 1 139 GLN 139 160 160 GLN GLN B . n 
B 1 140 GLU 140 161 161 GLU GLU B . n 
B 1 141 THR 141 162 162 THR THR B . n 
B 1 142 VAL 142 163 163 VAL VAL B . n 
B 1 143 SER 143 164 164 SER SER B . n 
B 1 144 VAL 144 165 165 VAL VAL B . n 
B 1 145 LEU 145 166 166 LEU LEU B . n 
B 1 146 MET 146 167 167 MET MET B . n 
B 1 147 GLY 147 168 168 GLY GLY B . n 
B 1 148 LEU 148 169 169 LEU LEU B . n 
B 1 149 GLN 149 170 170 GLN GLN B . n 
B 1 150 ASP 150 171 171 ASP ASP B . n 
B 1 151 GLN 151 172 172 GLN GLN B . n 
B 1 152 ILE 152 173 173 ILE ILE B . n 
B 1 153 ASN 153 174 174 ASN ASN B . n 
B 1 154 THR 154 175 175 THR THR B . n 
B 1 155 ASN 155 176 176 ASN ASN B . n 
B 1 156 LEU 156 177 177 LEU LEU B . n 
B 1 157 VAL 157 178 178 VAL VAL B . n 
B 1 158 PRO 158 179 179 PRO PRO B . n 
B 1 159 LYS 159 180 180 LYS LYS B . n 
B 1 160 ILE 160 181 181 ILE ILE B . n 
B 1 161 ASN 161 182 182 ASN ASN B . n 
B 1 162 ILE 162 183 183 ILE ILE B . n 
B 1 163 LEU 163 184 184 LEU LEU B . n 
B 1 164 SER 164 185 185 SER SER B . n 
B 1 165 CYS 165 186 186 CYS CYS B . n 
B 1 166 LYS 166 187 187 LYS LYS B . n 
B 1 167 GLN 167 188 188 GLN GLN B . n 
B 1 168 LEU 168 189 189 LEU LEU B . n 
B 1 169 SER 169 190 190 SER SER B . n 
B 1 170 ASN 170 191 191 ASN ASN B . n 
B 1 171 THR 171 192 192 THR THR B . n 
B 1 172 LEU 172 193 193 LEU LEU B . n 
B 1 173 ASN 173 194 194 ASN ASN B . n 
B 1 174 ILE 174 195 195 ILE ILE B . n 
B 1 175 MET 175 196 196 MET MET B . n 
B 1 176 LEU 176 197 197 LEU LEU B . n 
B 1 177 LEU 177 198 198 LEU LEU B . n 
B 1 178 GLN 178 199 199 GLN GLN B . n 
B 1 179 TYR 179 200 200 TYR TYR B . n 
B 1 180 TYR 180 201 201 TYR TYR B . n 
B 1 181 SER 181 202 202 SER SER B . n 
B 1 182 GLN 182 203 203 GLN GLN B . n 
B 1 183 ILE 183 204 204 ILE ILE B . n 
B 1 184 LEU 184 205 205 LEU LEU B . n 
B 1 185 THR 185 206 206 THR THR B . n 
B 1 186 VAL 186 207 207 VAL VAL B . n 
B 1 187 PHE 187 208 208 PHE PHE B . n 
B 1 188 GLY 188 209 209 GLY GLY B . n 
B 1 189 PRO 189 210 210 PRO PRO B . n 
B 1 190 ASN 190 211 211 ASN ASN B . n 
B 1 191 LEU 191 212 212 LEU LEU B . n 
B 1 192 ARG 192 213 213 ARG ARG B . n 
B 1 193 ASP 193 214 214 ASP ASP B . n 
B 1 194 PRO 194 215 215 PRO PRO B . n 
B 1 195 ALA 195 216 216 ALA ALA B . n 
B 1 196 THR 196 217 217 THR THR B . n 
B 1 197 VAL 197 218 218 VAL VAL B . n 
B 1 198 PRO 198 219 219 PRO PRO B . n 
B 1 199 VAL 199 220 220 VAL VAL B . n 
B 1 200 SER 200 221 221 SER SER B . n 
B 1 201 ILE 201 222 222 ILE ILE B . n 
B 1 202 GLN 202 223 223 GLN GLN B . n 
B 1 203 ALA 203 224 224 ALA ALA B . n 
B 1 204 LEU 204 225 225 LEU LEU B . n 
B 1 205 SER 205 226 226 SER SER B . n 
B 1 206 GLN 206 227 227 GLN GLN B . n 
B 1 207 LEU 207 228 228 LEU LEU B . n 
B 1 208 PHE 208 229 229 PHE PHE B . n 
B 1 209 GLU 209 230 230 GLU GLU B . n 
B 1 210 GLY 210 231 231 GLY GLY B . n 
B 1 211 ASN 211 232 232 ASN ASN B . n 
B 1 212 LEU 212 233 233 LEU LEU B . n 
B 1 213 GLU 213 234 234 GLU GLU B . n 
B 1 214 LEU 214 235 235 LEU LEU B . n 
B 1 215 LEU 215 236 236 LEU LEU B . n 
B 1 216 THR 216 237 237 THR THR B . n 
B 1 217 SER 217 238 238 SER SER B . n 
B 1 218 SER 218 239 239 SER SER B . n 
B 1 219 LEU 219 240 240 LEU LEU B . n 
B 1 220 GLY 220 241 241 GLY GLY B . n 
B 1 221 ILE 221 242 242 ILE ILE B . n 
B 1 222 SER 222 243 243 SER SER B . n 
B 1 223 SER 223 244 244 SER SER B . n 
B 1 224 THR 224 245 245 THR THR B . n 
B 1 225 ASP 225 246 246 ASP ASP B . n 
B 1 226 PHE 226 247 247 PHE PHE B . n 
B 1 227 ASN 227 248 248 ASN ASN B . n 
B 1 228 ASP 228 249 249 ASP ASP B . n 
B 1 229 LEU 229 250 250 LEU LEU B . n 
B 1 230 LEU 230 251 251 LEU LEU B . n 
B 1 231 THR 231 252 252 THR THR B . n 
B 1 232 GLY 232 253 253 GLY GLY B . n 
B 1 233 LYS 233 254 254 LYS LYS B . n 
B 1 234 LEU 234 255 255 LEU LEU B . n 
B 1 235 ILE 235 256 256 ILE ILE B . n 
B 1 236 THR 236 257 257 THR THR B . n 
B 1 237 GLY 237 258 258 GLY GLY B . n 
B 1 238 SER 238 259 259 SER SER B . n 
B 1 239 ILE 239 260 260 ILE ILE B . n 
B 1 240 ILE 240 261 261 ILE ILE B . n 
B 1 241 TRP 241 262 262 TRP TRP B . n 
B 1 242 ALA 242 263 263 ALA ALA B . n 
B 1 243 ASP 243 264 264 ASP ASP B . n 
B 1 244 THR 244 265 265 THR THR B . n 
B 1 245 GLN 245 266 266 GLN GLN B . n 
B 1 246 GLY 246 267 267 GLY GLY B . n 
B 1 247 HIS 247 268 268 HIS HIS B . n 
B 1 248 TYR 248 269 269 TYR TYR B . n 
B 1 249 LEU 249 270 270 LEU LEU B . n 
B 1 250 ILE 250 271 271 ILE ILE B . n 
B 1 251 LEU 251 272 272 LEU LEU B . n 
B 1 252 ARG 252 273 273 ARG ARG B . n 
B 1 253 VAL 253 274 274 VAL VAL B . n 
B 1 254 ASN 254 275 275 ASN ASN B . n 
B 1 255 ILE 255 276 276 ILE ILE B . n 
B 1 256 PRO 256 277 277 PRO PRO B . n 
B 1 257 ASP 257 278 278 ASP ASP B . n 
B 1 258 LEU 258 279 279 LEU LEU B . n 
B 1 259 ILE 259 280 280 ILE ILE B . n 
B 1 260 GLU 260 281 281 GLU GLU B . n 
B 1 261 VAL 261 282 282 VAL VAL B . n 
B 1 262 PRO 262 283 283 PRO PRO B . n 
B 1 263 GLY 263 284 284 GLY GLY B . n 
B 1 264 ALA 264 285 285 ALA ALA B . n 
B 1 265 VAL 265 286 286 VAL VAL B . n 
B 1 266 ILE 266 287 287 ILE ILE B . n 
B 1 267 GLN 267 288 288 GLN GLN B . n 
B 1 268 GLU 268 289 289 GLU GLU B . n 
B 1 269 PHE 269 290 290 PHE PHE B . n 
B 1 270 ILE 270 291 291 ILE ILE B . n 
B 1 271 LYS 271 292 292 LYS LYS B . n 
B 1 272 ILE 272 293 293 ILE ILE B . n 
B 1 273 GLY 273 294 294 GLY GLY B . n 
B 1 274 TYR 274 295 295 TYR TYR B . n 
B 1 275 ASN 275 296 296 ASN ASN B . n 
B 1 276 PHE 276 297 297 PHE PHE B . n 
B 1 277 GLY 277 298 298 GLY GLY B . n 
B 1 278 GLY 278 299 299 GLY GLY B . n 
B 1 279 SER 279 300 300 SER SER B . n 
B 1 280 LEU 280 301 301 LEU LEU B . n 
B 1 281 TRP 281 302 302 TRP TRP B . n 
B 1 282 MET 282 303 303 MET MET B . n 
B 1 283 PRO 283 304 304 PRO PRO B . n 
B 1 284 THR 284 305 305 THR THR B . n 
B 1 285 ILE 285 306 306 ILE ILE B . n 
B 1 286 PRO 286 307 307 PRO PRO B . n 
B 1 287 ASN 287 308 308 ASN ASN B . n 
B 1 288 LYS 288 309 309 LYS LYS B . n 
B 1 289 ILE 289 310 310 ILE ILE B . n 
B 1 290 ILE 290 311 311 ILE ILE B . n 
B 1 291 ILE 291 312 312 ILE ILE B . n 
B 1 292 ARG 292 313 313 ARG ARG B . n 
B 1 293 GLY 293 314 314 GLY GLY B . n 
B 1 294 TYR 294 315 315 TYR TYR B . n 
B 1 295 HIS 295 316 316 HIS HIS B . n 
B 1 296 LEU 296 317 317 LEU LEU B . n 
B 1 297 SER 297 318 318 SER SER B . n 
B 1 298 LEU 298 319 319 LEU LEU B . n 
B 1 299 ILE 299 320 320 ILE ILE B . n 
B 1 300 ASP 300 321 321 ASP ASP B . n 
B 1 301 SER 301 322 322 SER SER B . n 
B 1 302 THR 302 323 323 THR THR B . n 
B 1 303 ASN 303 324 324 ASN ASN B . n 
B 1 304 CYS 304 325 325 CYS CYS B . n 
B 1 305 ILE 305 326 326 ILE ILE B . n 
B 1 306 ILE 306 327 327 ILE ILE B . n 
B 1 307 THR 307 328 328 THR THR B . n 
B 1 308 ASP 308 329 329 ASP ASP B . n 
B 1 309 ASN 309 330 330 ASN ASN B . n 
B 1 310 SER 310 331 331 SER SER B . n 
B 1 311 TYR 311 332 332 TYR TYR B . n 
B 1 312 VAL 312 333 333 VAL VAL B . n 
B 1 313 CYS 313 334 334 CYS CYS B . n 
B 1 314 ASP 314 335 335 ASP ASP B . n 
B 1 315 ARG 315 336 336 ARG ARG B . n 
B 1 316 ASP 316 337 337 ASP ASP B . n 
B 1 317 TYR 317 338 338 TYR TYR B . n 
B 1 318 SER 318 339 339 SER SER B . n 
B 1 319 LEU 319 340 340 LEU LEU B . n 
B 1 320 PRO 320 341 341 PRO PRO B . n 
B 1 321 MET 321 342 342 MET MET B . n 
B 1 322 ASN 322 343 343 ASN ASN B . n 
B 1 323 PRO 323 344 344 PRO PRO B . n 
B 1 324 ILE 324 345 345 ILE ILE B . n 
B 1 325 LEU 325 346 346 LEU LEU B . n 
B 1 326 ARG 326 347 347 ARG ARG B . n 
B 1 327 GLU 327 348 348 GLU GLU B . n 
B 1 328 CYS 328 349 349 CYS CYS B . n 
B 1 329 PHE 329 350 350 PHE PHE B . n 
B 1 330 GLU 330 351 351 GLU GLU B . n 
B 1 331 GLY 331 352 352 GLY GLY B . n 
B 1 332 ASN 332 353 353 ASN ASN B . n 
B 1 333 THR 333 354 354 THR THR B . n 
B 1 334 SER 334 355 355 SER SER B . n 
B 1 335 SER 335 356 356 SER SER B . n 
B 1 336 CYS 336 357 357 CYS CYS B . n 
B 1 337 GLY 337 358 358 GLY GLY B . n 
B 1 338 ARG 338 359 359 ARG ARG B . n 
B 1 339 GLU 339 360 360 GLU GLU B . n 
B 1 340 MET 340 361 361 MET MET B . n 
B 1 341 VAL 341 362 362 VAL VAL B . n 
B 1 342 LEU 342 363 363 LEU LEU B . n 
B 1 343 ASN 343 364 364 ASN ASN B . n 
B 1 344 SER 344 365 365 SER SER B . n 
B 1 345 TYR 345 366 366 TYR TYR B . n 
B 1 346 ILE 346 367 367 ILE ILE B . n 
B 1 347 PRO 347 368 368 PRO PRO B . n 
B 1 348 LEU 348 369 369 LEU LEU B . n 
B 1 349 TYR 349 370 370 TYR TYR B . n 
B 1 350 ALA 350 371 371 ALA ALA B . n 
B 1 351 LEU 351 372 372 LEU LEU B . n 
B 1 352 SER 352 373 373 SER SER B . n 
B 1 353 GLU 353 374 374 GLU GLU B . n 
B 1 354 GLY 354 375 375 GLY GLY B . n 
B 1 355 VAL 355 376 376 VAL VAL B . n 
B 1 356 ILE 356 377 377 ILE ILE B . n 
B 1 357 TYR 357 378 378 TYR TYR B . n 
B 1 358 ALA 358 379 379 ALA ALA B . n 
B 1 359 ASN 359 380 380 ASN ASN B . n 
B 1 360 CYS 360 381 381 CYS CYS B . n 
B 1 361 LEU 361 382 382 LEU LEU B . n 
B 1 362 ALA 362 383 383 ALA ALA B . n 
B 1 363 THR 363 384 384 THR THR B . n 
B 1 364 SER 364 385 385 SER SER B . n 
B 1 365 CYS 365 386 386 CYS CYS B . n 
B 1 366 LYS 366 387 387 LYS LYS B . n 
B 1 367 CYS 367 388 388 CYS CYS B . n 
B 1 368 ALA 368 389 389 ALA ALA B . n 
B 1 369 THR 369 390 390 THR THR B . n 
B 1 370 THR 370 391 391 THR THR B . n 
B 1 371 ASN 371 392 392 ASN ASN B . n 
B 1 372 LYS 372 393 393 LYS LYS B . n 
B 1 373 PRO 373 394 394 PRO PRO B . n 
B 1 374 ILE 374 395 395 ILE ILE B . n 
B 1 375 VAL 375 396 396 VAL VAL B . n 
B 1 376 GLN 376 397 397 GLN GLN B . n 
B 1 377 SER 377 398 398 SER SER B . n 
B 1 378 THR 378 399 399 THR THR B . n 
B 1 379 SER 379 400 400 SER SER B . n 
B 1 380 THR 380 401 401 THR THR B . n 
B 1 381 VAL 381 402 402 VAL VAL B . n 
B 1 382 ILE 382 403 403 ILE ILE B . n 
B 1 383 THR 383 404 404 THR THR B . n 
B 1 384 MET 384 405 405 MET MET B . n 
B 1 385 ILE 385 406 406 ILE ILE B . n 
B 1 386 ASP 386 407 407 ASP ASP B . n 
B 1 387 ASN 387 408 408 ASN ASN B . n 
B 1 388 SER 388 409 409 SER SER B . n 
B 1 389 LYS 389 410 410 LYS LYS B . n 
B 1 390 CYS 390 411 411 CYS CYS B . n 
B 1 391 PRO 391 412 412 PRO PRO B . n 
B 1 392 VAL 392 413 413 VAL VAL B . n 
B 1 393 VAL 393 414 414 VAL VAL B . n 
B 1 394 GLU 394 415 415 GLU GLU B . n 
B 1 395 VAL 395 416 416 VAL VAL B . n 
B 1 396 GLY 396 417 417 GLY GLY B . n 
B 1 397 LYS 397 418 418 LYS LYS B . n 
B 1 398 GLN 398 419 419 GLN GLN B . n 
B 1 399 MET 399 420 420 MET MET B . n 
B 1 400 ILE 400 421 421 ILE ILE B . n 
B 1 401 SER 401 422 422 SER SER B . n 
B 1 402 VAL 402 423 423 VAL VAL B . n 
B 1 403 GLY 403 424 424 GLY GLY B . n 
B 1 404 SER 404 425 425 SER SER B . n 
B 1 405 TYR 405 426 426 TYR TYR B . n 
B 1 406 LEU 406 427 427 LEU LEU B . n 
B 1 407 GLY 407 428 428 GLY GLY B . n 
B 1 408 GLN 408 429 429 GLN GLN B . n 
B 1 409 VAL 409 430 430 VAL VAL B . n 
B 1 410 SER 410 431 431 SER SER B . n 
B 1 411 PRO 411 432 432 PRO PRO B . n 
B 1 412 ASN 412 433 433 ASN ASN B . n 
B 1 413 ASN 413 434 434 ASN ASN B . n 
B 1 414 LEU 414 435 435 LEU LEU B . n 
B 1 415 THR 415 436 436 THR THR B . n 
B 1 416 ILE 416 437 437 ILE ILE B . n 
B 1 417 GLU 417 438 438 GLU GLU B . n 
B 1 418 ILE 418 439 439 ILE ILE B . n 
B 1 419 GLY 419 440 440 GLY GLY B . n 
B 1 420 PRO 420 441 441 PRO PRO B . n 
B 1 421 PRO 421 442 442 PRO PRO B . n 
B 1 422 VAL 422 443 443 VAL VAL B . n 
B 1 423 TYR 423 444 444 TYR TYR B . n 
B 1 424 THR 424 445 445 THR THR B . n 
B 1 425 GLU 425 446 446 GLU GLU B . n 
B 1 426 PRO 426 447 447 PRO PRO B . n 
B 1 427 VAL 427 448 448 VAL VAL B . n 
B 1 428 ASP 428 449 449 ASP ASP B . n 
B 1 429 ILE 429 450 450 ILE ILE B . n 
B 1 430 THR 430 451 451 THR THR B . n 
B 1 431 ASN 431 452 452 ASN ASN B . n 
B 1 432 GLN 432 453 453 GLN GLN B . n 
B 1 433 LEU 433 454 454 LEU LEU B . n 
B 1 434 GLY 434 455 455 GLY GLY B . n 
B 1 435 ASN 435 456 456 ASN ASN B . n 
B 1 436 ILE 436 457 457 ILE ILE B . n 
B 1 437 ASN 437 458 458 ASN ASN B . n 
B 1 438 GLU 438 459 459 GLU GLU B . n 
B 1 439 THR 439 460 460 THR THR B . n 
B 1 440 LEU 440 461 461 LEU LEU B . n 
B 1 441 SER 441 462 462 SER SER B . n 
B 1 442 LYS 442 463 463 LYS LYS B . n 
B 1 443 THR 443 464 464 THR THR B . n 
B 1 444 LEU 444 465 465 LEU LEU B . n 
B 1 445 ASP 445 466 466 ASP ASP B . n 
B 1 446 LEU 446 467 467 LEU LEU B . n 
B 1 447 ILE 447 468 468 ILE ILE B . n 
B 1 448 LYS 448 469 469 LYS LYS B . n 
B 1 449 GLN 449 470 470 GLN GLN B . n 
B 1 450 SER 450 471 471 SER SER B . n 
B 1 451 ASN 451 472 472 ASN ASN B . n 
B 1 452 SER 452 473 473 SER SER B . n 
B 1 453 ILE 453 474 474 ILE ILE B . n 
B 1 454 LEU 454 475 475 LEU LEU B . n 
B 1 455 ASP 455 476 476 ASP ASP B . n 
B 1 456 MET 456 477 477 MET MET B . n 
B 1 457 ILE 457 478 478 ILE ILE B . n 
B 1 458 THR 458 479 479 THR THR B . n 
B 1 459 GLY 459 480 480 GLY GLY B . n 
B 1 460 GLY 460 481 481 GLY GLY B . n 
B 1 461 LEU 461 482 482 LEU LEU B . n 
B 1 462 GLY 462 483 ?   ?   ?   B . n 
B 1 463 SER 463 484 ?   ?   ?   B . n 
B 1 464 GLY 464 485 ?   ?   ?   B . n 
B 1 465 TYR 465 486 ?   ?   ?   B . n 
B 1 466 ILE 466 487 ?   ?   ?   B . n 
B 1 467 PRO 467 488 ?   ?   ?   B . n 
B 1 468 GLU 468 489 ?   ?   ?   B . n 
B 1 469 ALA 469 490 ?   ?   ?   B . n 
B 1 470 PRO 470 491 ?   ?   ?   B . n 
B 1 471 ARG 471 492 ?   ?   ?   B . n 
B 1 472 ASP 472 493 ?   ?   ?   B . n 
B 1 473 GLY 473 494 ?   ?   ?   B . n 
B 1 474 GLN 474 495 ?   ?   ?   B . n 
B 1 475 ALA 475 496 ?   ?   ?   B . n 
B 1 476 TYR 476 497 ?   ?   ?   B . n 
B 1 477 VAL 477 498 ?   ?   ?   B . n 
B 1 478 ARG 478 499 ?   ?   ?   B . n 
B 1 479 LYS 479 500 ?   ?   ?   B . n 
B 1 480 ASP 480 501 ?   ?   ?   B . n 
B 1 481 GLY 481 502 ?   ?   ?   B . n 
B 1 482 GLU 482 503 ?   ?   ?   B . n 
B 1 483 TRP 483 504 ?   ?   ?   B . n 
B 1 484 VAL 484 505 ?   ?   ?   B . n 
B 1 485 LEU 485 506 ?   ?   ?   B . n 
B 1 486 LEU 486 507 ?   ?   ?   B . n 
B 1 487 SER 487 508 ?   ?   ?   B . n 
B 1 488 THR 488 509 ?   ?   ?   B . n 
B 1 489 PHE 489 510 ?   ?   ?   B . n 
B 1 490 LEU 490 511 ?   ?   ?   B . n 
B 1 491 GLY 491 512 ?   ?   ?   B . n 
B 1 492 ARG 492 513 ?   ?   ?   B . n 
B 1 493 SER 493 514 ?   ?   ?   B . n 
B 1 494 LEU 494 515 ?   ?   ?   B . n 
B 1 495 GLU 495 516 ?   ?   ?   B . n 
B 1 496 VAL 496 517 ?   ?   ?   B . n 
B 1 497 LEU 497 518 ?   ?   ?   B . n 
B 1 498 PHE 498 519 ?   ?   ?   B . n 
B 1 499 GLN 499 520 ?   ?   ?   B . n 
B 1 500 GLY 500 521 ?   ?   ?   B . n 
B 1 501 PRO 501 522 ?   ?   ?   B . n 
B 1 502 GLY 502 523 ?   ?   ?   B . n 
B 1 503 HIS 503 524 ?   ?   ?   B . n 
B 1 504 HIS 504 525 ?   ?   ?   B . n 
B 1 505 HIS 505 526 ?   ?   ?   B . n 
B 1 506 HIS 506 527 ?   ?   ?   B . n 
B 1 507 HIS 507 528 ?   ?   ?   B . n 
B 1 508 HIS 508 529 ?   ?   ?   B . n 
B 1 509 HIS 509 530 ?   ?   ?   B . n 
B 1 510 HIS 510 531 ?   ?   ?   B . n 
B 1 511 SER 511 532 ?   ?   ?   B . n 
B 1 512 ALA 512 533 ?   ?   ?   B . n 
B 1 513 TRP 513 534 ?   ?   ?   B . n 
B 1 514 SER 514 535 ?   ?   ?   B . n 
B 1 515 HIS 515 536 ?   ?   ?   B . n 
B 1 516 PRO 516 537 ?   ?   ?   B . n 
B 1 517 GLN 517 538 ?   ?   ?   B . n 
B 1 518 PHE 518 539 ?   ?   ?   B . n 
B 1 519 GLU 519 540 ?   ?   ?   B . n 
B 1 520 LYS 520 541 ?   ?   ?   B . n 
B 1 521 GLY 521 542 ?   ?   ?   B . n 
B 1 522 GLY 522 543 ?   ?   ?   B . n 
B 1 523 GLY 523 544 ?   ?   ?   B . n 
B 1 524 SER 524 545 ?   ?   ?   B . n 
B 1 525 GLY 525 546 ?   ?   ?   B . n 
B 1 526 GLY 526 547 ?   ?   ?   B . n 
B 1 527 GLY 527 548 ?   ?   ?   B . n 
B 1 528 GLY 528 549 ?   ?   ?   B . n 
B 1 529 SER 529 550 ?   ?   ?   B . n 
B 1 530 GLY 530 551 ?   ?   ?   B . n 
B 1 531 GLY 531 552 ?   ?   ?   B . n 
B 1 532 SER 532 553 ?   ?   ?   B . n 
B 1 533 ALA 533 554 ?   ?   ?   B . n 
B 1 534 TRP 534 555 ?   ?   ?   B . n 
B 1 535 SER 535 556 ?   ?   ?   B . n 
B 1 536 HIS 536 557 ?   ?   ?   B . n 
B 1 537 PRO 537 558 ?   ?   ?   B . n 
B 1 538 GLN 538 559 ?   ?   ?   B . n 
B 1 539 PHE 539 560 ?   ?   ?   B . n 
B 1 540 GLU 540 561 ?   ?   ?   B . n 
B 1 541 LYS 541 562 ?   ?   ?   B . n 
C 1 1   VAL 1   22  22  VAL VAL C . n 
C 1 2   ASP 2   23  23  ASP ASP C . n 
C 1 3   PHE 3   24  24  PHE PHE C . n 
C 1 4   GLU 4   25  25  GLU GLU C . n 
C 1 5   ARG 5   26  26  ARG ARG C . n 
C 1 6   LEU 6   27  27  LEU LEU C . n 
C 1 7   ALA 7   28  28  ALA ALA C . n 
C 1 8   SER 8   29  29  SER SER C . n 
C 1 9   ILE 9   30  30  ILE ILE C . n 
C 1 10  GLY 10  31  31  GLY GLY C . n 
C 1 11  GLY 11  32  32  GLY GLY C . n 
C 1 12  ILE 12  33  33  ILE ILE C . n 
C 1 13  LYS 13  34  34  LYS LYS C . n 
C 1 14  GLY 14  35  35  GLY GLY C . n 
C 1 15  HIS 15  36  36  HIS HIS C . n 
C 1 16  SER 16  37  37  SER SER C . n 
C 1 17  LYS 17  38  38  LYS LYS C . n 
C 1 18  LEU 18  39  39  LEU LEU C . n 
C 1 19  TYR 19  40  40  TYR TYR C . n 
C 1 20  LYS 20  41  41  LYS LYS C . n 
C 1 21  ILE 21  42  42  ILE ILE C . n 
C 1 22  LYS 22  43  43  LYS LYS C . n 
C 1 23  GLY 23  44  44  GLY GLY C . n 
C 1 24  HIS 24  45  45  HIS HIS C . n 
C 1 25  PRO 25  46  46  PRO PRO C . n 
C 1 26  THR 26  47  47  THR THR C . n 
C 1 27  THR 27  48  48  THR THR C . n 
C 1 28  LYS 28  49  49  LYS LYS C . n 
C 1 29  ASP 29  50  50  ASP ASP C . n 
C 1 30  ILE 30  51  51  ILE ILE C . n 
C 1 31  VAL 31  52  52  VAL VAL C . n 
C 1 32  ILE 32  53  53  ILE ILE C . n 
C 1 33  LYS 33  54  54  LYS LYS C . n 
C 1 34  LEU 34  55  55  LEU LEU C . n 
C 1 35  VAL 35  56  56  VAL VAL C . n 
C 1 36  PRO 36  57  57  PRO PRO C . n 
C 1 37  ASN 37  58  58  ASN ASN C . n 
C 1 38  LEU 38  59  59  LEU LEU C . n 
C 1 39  ASN 39  60  60  ASN ASN C . n 
C 1 40  ASN 40  61  61  ASN ASN C . n 
C 1 41  LEU 41  62  62  LEU LEU C . n 
C 1 42  THR 42  63  63  THR THR C . n 
C 1 43  VAL 43  64  64  VAL VAL C . n 
C 1 44  CYS 44  65  65  CYS CYS C . n 
C 1 45  SER 45  66  66  SER SER C . n 
C 1 46  GLU 46  67  67  GLU GLU C . n 
C 1 47  MET 47  68  68  MET MET C . n 
C 1 48  SER 48  69  69  SER SER C . n 
C 1 49  ILE 49  70  70  ILE ILE C . n 
C 1 50  ASP 50  71  71  ASP ASP C . n 
C 1 51  GLY 51  72  72  GLY GLY C . n 
C 1 52  TYR 52  73  73  TYR TYR C . n 
C 1 53  LEU 53  74  74  LEU LEU C . n 
C 1 54  ASN 54  75  75  ASN ASN C . n 
C 1 55  LEU 55  76  76  LEU LEU C . n 
C 1 56  ILE 56  77  77  ILE ILE C . n 
C 1 57  ASN 57  78  78  ASN ASN C . n 
C 1 58  ALA 58  79  79  ALA ALA C . n 
C 1 59  VAL 59  80  80  VAL VAL C . n 
C 1 60  ILE 60  81  81  ILE ILE C . n 
C 1 61  ILE 61  82  82  ILE ILE C . n 
C 1 62  PRO 62  83  83  PRO PRO C . n 
C 1 63  ILE 63  84  84  ILE ILE C . n 
C 1 64  SER 64  85  85  SER SER C . n 
C 1 65  GLN 65  86  86  GLN GLN C . n 
C 1 66  SER 66  87  87  SER SER C . n 
C 1 67  LEU 67  88  88  LEU LEU C . n 
C 1 68  GLU 68  89  89  GLU GLU C . n 
C 1 69  LEU 69  90  90  LEU LEU C . n 
C 1 70  MET 70  91  91  MET MET C . n 
C 1 71  ARG 71  92  92  ARG ARG C . n 
C 1 72  ASN 72  93  93  ASN ASN C . n 
C 1 73  ASN 73  94  94  ASN ASN C . n 
C 1 74  VAL 74  95  95  VAL VAL C . n 
C 1 75  LYS 75  96  96  LYS LYS C . n 
C 1 76  ASP 76  97  97  ASP ASP C . n 
C 1 77  GLY 77  98  98  GLY GLY C . n 
C 1 78  THR 78  99  99  THR THR C . n 
C 1 79  PRO 79  100 100 PRO PRO C . n 
C 1 80  ASN 80  101 101 ASN ASN C . n 
C 1 81  GLU 81  102 102 GLU GLU C . n 
C 1 82  ASN 82  103 103 ASN ASN C . n 
C 1 83  ILE 83  104 104 ILE ILE C . n 
C 1 84  PHE 84  105 105 PHE PHE C . n 
C 1 85  GLY 85  106 106 GLY GLY C . n 
C 1 86  ALA 86  107 107 ALA ALA C . n 
C 1 87  ILE 87  108 108 ILE ILE C . n 
C 1 88  VAL 88  109 109 VAL VAL C . n 
C 1 89  ALA 89  110 110 ALA ALA C . n 
C 1 90  GLY 90  111 111 GLY GLY C . n 
C 1 91  ALA 91  112 112 ALA ALA C . n 
C 1 92  ALA 92  113 113 ALA ALA C . n 
C 1 93  LEU 93  114 114 LEU LEU C . n 
C 1 94  GLY 94  115 115 GLY GLY C . n 
C 1 95  ILE 95  116 116 ILE ILE C . n 
C 1 96  ALA 96  117 117 ALA ALA C . n 
C 1 97  THR 97  118 118 THR THR C . n 
C 1 98  ALA 98  119 119 ALA ALA C . n 
C 1 99  ALA 99  120 120 ALA ALA C . n 
C 1 100 GLN 100 121 121 GLN GLN C . n 
C 1 101 VAL 101 122 122 VAL VAL C . n 
C 1 102 THR 102 123 123 THR THR C . n 
C 1 103 SER 103 124 124 SER SER C . n 
C 1 104 VAL 104 125 125 VAL VAL C . n 
C 1 105 VAL 105 126 126 VAL VAL C . n 
C 1 106 ALA 106 127 127 ALA ALA C . n 
C 1 107 LEU 107 128 128 LEU LEU C . n 
C 1 108 HIS 108 129 129 HIS HIS C . n 
C 1 109 LYS 109 130 130 LYS LYS C . n 
C 1 110 SER 110 131 131 SER SER C . n 
C 1 111 ASN 111 132 132 ASN ASN C . n 
C 1 112 GLN 112 133 133 GLN GLN C . n 
C 1 113 ASN 113 134 134 ASN ASN C . n 
C 1 114 ALA 114 135 135 ALA ALA C . n 
C 1 115 ALA 115 136 136 ALA ALA C . n 
C 1 116 LYS 116 137 137 LYS LYS C . n 
C 1 117 ILE 117 138 138 ILE ILE C . n 
C 1 118 ASN 118 139 139 ASN ASN C . n 
C 1 119 SER 119 140 140 SER SER C . n 
C 1 120 LEU 120 141 141 LEU LEU C . n 
C 1 121 ARG 121 142 142 ARG ARG C . n 
C 1 122 ASP 122 143 143 ASP ASP C . n 
C 1 123 SER 123 144 144 SER SER C . n 
C 1 124 ILE 124 145 145 ILE ILE C . n 
C 1 125 THR 125 146 146 THR THR C . n 
C 1 126 LYS 126 147 147 LYS LYS C . n 
C 1 127 THR 127 148 148 THR THR C . n 
C 1 128 ASN 128 149 149 ASN ASN C . n 
C 1 129 GLN 129 150 150 GLN GLN C . n 
C 1 130 ALA 130 151 151 ALA ALA C . n 
C 1 131 VAL 131 152 152 VAL VAL C . n 
C 1 132 GLU 132 153 153 GLU GLU C . n 
C 1 133 GLN 133 154 154 GLN GLN C . n 
C 1 134 LEU 134 155 155 LEU LEU C . n 
C 1 135 SER 135 156 156 SER SER C . n 
C 1 136 LEU 136 157 157 LEU LEU C . n 
C 1 137 GLY 137 158 158 GLY GLY C . n 
C 1 138 VAL 138 159 159 VAL VAL C . n 
C 1 139 GLN 139 160 160 GLN GLN C . n 
C 1 140 GLU 140 161 161 GLU GLU C . n 
C 1 141 THR 141 162 162 THR THR C . n 
C 1 142 VAL 142 163 163 VAL VAL C . n 
C 1 143 SER 143 164 164 SER SER C . n 
C 1 144 VAL 144 165 165 VAL VAL C . n 
C 1 145 LEU 145 166 166 LEU LEU C . n 
C 1 146 MET 146 167 167 MET MET C . n 
C 1 147 GLY 147 168 168 GLY GLY C . n 
C 1 148 LEU 148 169 169 LEU LEU C . n 
C 1 149 GLN 149 170 170 GLN GLN C . n 
C 1 150 ASP 150 171 171 ASP ASP C . n 
C 1 151 GLN 151 172 172 GLN GLN C . n 
C 1 152 ILE 152 173 173 ILE ILE C . n 
C 1 153 ASN 153 174 174 ASN ASN C . n 
C 1 154 THR 154 175 175 THR THR C . n 
C 1 155 ASN 155 176 176 ASN ASN C . n 
C 1 156 LEU 156 177 177 LEU LEU C . n 
C 1 157 VAL 157 178 178 VAL VAL C . n 
C 1 158 PRO 158 179 179 PRO PRO C . n 
C 1 159 LYS 159 180 180 LYS LYS C . n 
C 1 160 ILE 160 181 181 ILE ILE C . n 
C 1 161 ASN 161 182 182 ASN ASN C . n 
C 1 162 ILE 162 183 183 ILE ILE C . n 
C 1 163 LEU 163 184 184 LEU LEU C . n 
C 1 164 SER 164 185 185 SER SER C . n 
C 1 165 CYS 165 186 186 CYS CYS C . n 
C 1 166 LYS 166 187 187 LYS LYS C . n 
C 1 167 GLN 167 188 188 GLN GLN C . n 
C 1 168 LEU 168 189 189 LEU LEU C . n 
C 1 169 SER 169 190 190 SER SER C . n 
C 1 170 ASN 170 191 191 ASN ASN C . n 
C 1 171 THR 171 192 192 THR THR C . n 
C 1 172 LEU 172 193 193 LEU LEU C . n 
C 1 173 ASN 173 194 194 ASN ASN C . n 
C 1 174 ILE 174 195 195 ILE ILE C . n 
C 1 175 MET 175 196 196 MET MET C . n 
C 1 176 LEU 176 197 197 LEU LEU C . n 
C 1 177 LEU 177 198 198 LEU LEU C . n 
C 1 178 GLN 178 199 199 GLN GLN C . n 
C 1 179 TYR 179 200 200 TYR TYR C . n 
C 1 180 TYR 180 201 201 TYR TYR C . n 
C 1 181 SER 181 202 202 SER SER C . n 
C 1 182 GLN 182 203 203 GLN GLN C . n 
C 1 183 ILE 183 204 204 ILE ILE C . n 
C 1 184 LEU 184 205 205 LEU LEU C . n 
C 1 185 THR 185 206 206 THR THR C . n 
C 1 186 VAL 186 207 207 VAL VAL C . n 
C 1 187 PHE 187 208 208 PHE PHE C . n 
C 1 188 GLY 188 209 209 GLY GLY C . n 
C 1 189 PRO 189 210 210 PRO PRO C . n 
C 1 190 ASN 190 211 211 ASN ASN C . n 
C 1 191 LEU 191 212 212 LEU LEU C . n 
C 1 192 ARG 192 213 213 ARG ARG C . n 
C 1 193 ASP 193 214 214 ASP ASP C . n 
C 1 194 PRO 194 215 215 PRO PRO C . n 
C 1 195 ALA 195 216 216 ALA ALA C . n 
C 1 196 THR 196 217 217 THR THR C . n 
C 1 197 VAL 197 218 218 VAL VAL C . n 
C 1 198 PRO 198 219 219 PRO PRO C . n 
C 1 199 VAL 199 220 220 VAL VAL C . n 
C 1 200 SER 200 221 221 SER SER C . n 
C 1 201 ILE 201 222 222 ILE ILE C . n 
C 1 202 GLN 202 223 223 GLN GLN C . n 
C 1 203 ALA 203 224 224 ALA ALA C . n 
C 1 204 LEU 204 225 225 LEU LEU C . n 
C 1 205 SER 205 226 226 SER SER C . n 
C 1 206 GLN 206 227 227 GLN GLN C . n 
C 1 207 LEU 207 228 228 LEU LEU C . n 
C 1 208 PHE 208 229 229 PHE PHE C . n 
C 1 209 GLU 209 230 230 GLU GLU C . n 
C 1 210 GLY 210 231 231 GLY GLY C . n 
C 1 211 ASN 211 232 232 ASN ASN C . n 
C 1 212 LEU 212 233 233 LEU LEU C . n 
C 1 213 GLU 213 234 234 GLU GLU C . n 
C 1 214 LEU 214 235 235 LEU LEU C . n 
C 1 215 LEU 215 236 236 LEU LEU C . n 
C 1 216 THR 216 237 237 THR THR C . n 
C 1 217 SER 217 238 238 SER SER C . n 
C 1 218 SER 218 239 239 SER SER C . n 
C 1 219 LEU 219 240 240 LEU LEU C . n 
C 1 220 GLY 220 241 241 GLY GLY C . n 
C 1 221 ILE 221 242 242 ILE ILE C . n 
C 1 222 SER 222 243 243 SER SER C . n 
C 1 223 SER 223 244 244 SER SER C . n 
C 1 224 THR 224 245 245 THR THR C . n 
C 1 225 ASP 225 246 246 ASP ASP C . n 
C 1 226 PHE 226 247 247 PHE PHE C . n 
C 1 227 ASN 227 248 248 ASN ASN C . n 
C 1 228 ASP 228 249 249 ASP ASP C . n 
C 1 229 LEU 229 250 250 LEU LEU C . n 
C 1 230 LEU 230 251 251 LEU LEU C . n 
C 1 231 THR 231 252 252 THR THR C . n 
C 1 232 GLY 232 253 253 GLY GLY C . n 
C 1 233 LYS 233 254 254 LYS LYS C . n 
C 1 234 LEU 234 255 255 LEU LEU C . n 
C 1 235 ILE 235 256 256 ILE ILE C . n 
C 1 236 THR 236 257 257 THR THR C . n 
C 1 237 GLY 237 258 258 GLY GLY C . n 
C 1 238 SER 238 259 259 SER SER C . n 
C 1 239 ILE 239 260 260 ILE ILE C . n 
C 1 240 ILE 240 261 261 ILE ILE C . n 
C 1 241 TRP 241 262 262 TRP TRP C . n 
C 1 242 ALA 242 263 263 ALA ALA C . n 
C 1 243 ASP 243 264 264 ASP ASP C . n 
C 1 244 THR 244 265 265 THR THR C . n 
C 1 245 GLN 245 266 266 GLN GLN C . n 
C 1 246 GLY 246 267 267 GLY GLY C . n 
C 1 247 HIS 247 268 268 HIS HIS C . n 
C 1 248 TYR 248 269 269 TYR TYR C . n 
C 1 249 LEU 249 270 270 LEU LEU C . n 
C 1 250 ILE 250 271 271 ILE ILE C . n 
C 1 251 LEU 251 272 272 LEU LEU C . n 
C 1 252 ARG 252 273 273 ARG ARG C . n 
C 1 253 VAL 253 274 274 VAL VAL C . n 
C 1 254 ASN 254 275 275 ASN ASN C . n 
C 1 255 ILE 255 276 276 ILE ILE C . n 
C 1 256 PRO 256 277 277 PRO PRO C . n 
C 1 257 ASP 257 278 278 ASP ASP C . n 
C 1 258 LEU 258 279 279 LEU LEU C . n 
C 1 259 ILE 259 280 280 ILE ILE C . n 
C 1 260 GLU 260 281 281 GLU GLU C . n 
C 1 261 VAL 261 282 282 VAL VAL C . n 
C 1 262 PRO 262 283 283 PRO PRO C . n 
C 1 263 GLY 263 284 284 GLY GLY C . n 
C 1 264 ALA 264 285 285 ALA ALA C . n 
C 1 265 VAL 265 286 286 VAL VAL C . n 
C 1 266 ILE 266 287 287 ILE ILE C . n 
C 1 267 GLN 267 288 288 GLN GLN C . n 
C 1 268 GLU 268 289 289 GLU GLU C . n 
C 1 269 PHE 269 290 290 PHE PHE C . n 
C 1 270 ILE 270 291 291 ILE ILE C . n 
C 1 271 LYS 271 292 292 LYS LYS C . n 
C 1 272 ILE 272 293 293 ILE ILE C . n 
C 1 273 GLY 273 294 294 GLY GLY C . n 
C 1 274 TYR 274 295 295 TYR TYR C . n 
C 1 275 ASN 275 296 296 ASN ASN C . n 
C 1 276 PHE 276 297 297 PHE PHE C . n 
C 1 277 GLY 277 298 298 GLY GLY C . n 
C 1 278 GLY 278 299 299 GLY GLY C . n 
C 1 279 SER 279 300 300 SER SER C . n 
C 1 280 LEU 280 301 301 LEU LEU C . n 
C 1 281 TRP 281 302 302 TRP TRP C . n 
C 1 282 MET 282 303 303 MET MET C . n 
C 1 283 PRO 283 304 304 PRO PRO C . n 
C 1 284 THR 284 305 305 THR THR C . n 
C 1 285 ILE 285 306 306 ILE ILE C . n 
C 1 286 PRO 286 307 307 PRO PRO C . n 
C 1 287 ASN 287 308 308 ASN ASN C . n 
C 1 288 LYS 288 309 309 LYS LYS C . n 
C 1 289 ILE 289 310 310 ILE ILE C . n 
C 1 290 ILE 290 311 311 ILE ILE C . n 
C 1 291 ILE 291 312 312 ILE ILE C . n 
C 1 292 ARG 292 313 313 ARG ARG C . n 
C 1 293 GLY 293 314 314 GLY GLY C . n 
C 1 294 TYR 294 315 315 TYR TYR C . n 
C 1 295 HIS 295 316 316 HIS HIS C . n 
C 1 296 LEU 296 317 317 LEU LEU C . n 
C 1 297 SER 297 318 318 SER SER C . n 
C 1 298 LEU 298 319 319 LEU LEU C . n 
C 1 299 ILE 299 320 320 ILE ILE C . n 
C 1 300 ASP 300 321 321 ASP ASP C . n 
C 1 301 SER 301 322 322 SER SER C . n 
C 1 302 THR 302 323 323 THR THR C . n 
C 1 303 ASN 303 324 324 ASN ASN C . n 
C 1 304 CYS 304 325 325 CYS CYS C . n 
C 1 305 ILE 305 326 326 ILE ILE C . n 
C 1 306 ILE 306 327 327 ILE ILE C . n 
C 1 307 THR 307 328 328 THR THR C . n 
C 1 308 ASP 308 329 329 ASP ASP C . n 
C 1 309 ASN 309 330 330 ASN ASN C . n 
C 1 310 SER 310 331 331 SER SER C . n 
C 1 311 TYR 311 332 332 TYR TYR C . n 
C 1 312 VAL 312 333 333 VAL VAL C . n 
C 1 313 CYS 313 334 334 CYS CYS C . n 
C 1 314 ASP 314 335 335 ASP ASP C . n 
C 1 315 ARG 315 336 336 ARG ARG C . n 
C 1 316 ASP 316 337 337 ASP ASP C . n 
C 1 317 TYR 317 338 338 TYR TYR C . n 
C 1 318 SER 318 339 339 SER SER C . n 
C 1 319 LEU 319 340 340 LEU LEU C . n 
C 1 320 PRO 320 341 341 PRO PRO C . n 
C 1 321 MET 321 342 342 MET MET C . n 
C 1 322 ASN 322 343 343 ASN ASN C . n 
C 1 323 PRO 323 344 344 PRO PRO C . n 
C 1 324 ILE 324 345 345 ILE ILE C . n 
C 1 325 LEU 325 346 346 LEU LEU C . n 
C 1 326 ARG 326 347 347 ARG ARG C . n 
C 1 327 GLU 327 348 348 GLU GLU C . n 
C 1 328 CYS 328 349 349 CYS CYS C . n 
C 1 329 PHE 329 350 350 PHE PHE C . n 
C 1 330 GLU 330 351 351 GLU GLU C . n 
C 1 331 GLY 331 352 352 GLY GLY C . n 
C 1 332 ASN 332 353 353 ASN ASN C . n 
C 1 333 THR 333 354 354 THR THR C . n 
C 1 334 SER 334 355 355 SER SER C . n 
C 1 335 SER 335 356 356 SER SER C . n 
C 1 336 CYS 336 357 357 CYS CYS C . n 
C 1 337 GLY 337 358 358 GLY GLY C . n 
C 1 338 ARG 338 359 359 ARG ARG C . n 
C 1 339 GLU 339 360 360 GLU GLU C . n 
C 1 340 MET 340 361 361 MET MET C . n 
C 1 341 VAL 341 362 362 VAL VAL C . n 
C 1 342 LEU 342 363 363 LEU LEU C . n 
C 1 343 ASN 343 364 364 ASN ASN C . n 
C 1 344 SER 344 365 365 SER SER C . n 
C 1 345 TYR 345 366 366 TYR TYR C . n 
C 1 346 ILE 346 367 367 ILE ILE C . n 
C 1 347 PRO 347 368 368 PRO PRO C . n 
C 1 348 LEU 348 369 369 LEU LEU C . n 
C 1 349 TYR 349 370 370 TYR TYR C . n 
C 1 350 ALA 350 371 371 ALA ALA C . n 
C 1 351 LEU 351 372 372 LEU LEU C . n 
C 1 352 SER 352 373 373 SER SER C . n 
C 1 353 GLU 353 374 374 GLU GLU C . n 
C 1 354 GLY 354 375 375 GLY GLY C . n 
C 1 355 VAL 355 376 376 VAL VAL C . n 
C 1 356 ILE 356 377 377 ILE ILE C . n 
C 1 357 TYR 357 378 378 TYR TYR C . n 
C 1 358 ALA 358 379 379 ALA ALA C . n 
C 1 359 ASN 359 380 380 ASN ASN C . n 
C 1 360 CYS 360 381 381 CYS CYS C . n 
C 1 361 LEU 361 382 382 LEU LEU C . n 
C 1 362 ALA 362 383 383 ALA ALA C . n 
C 1 363 THR 363 384 384 THR THR C . n 
C 1 364 SER 364 385 385 SER SER C . n 
C 1 365 CYS 365 386 386 CYS CYS C . n 
C 1 366 LYS 366 387 387 LYS LYS C . n 
C 1 367 CYS 367 388 388 CYS CYS C . n 
C 1 368 ALA 368 389 389 ALA ALA C . n 
C 1 369 THR 369 390 390 THR THR C . n 
C 1 370 THR 370 391 391 THR THR C . n 
C 1 371 ASN 371 392 392 ASN ASN C . n 
C 1 372 LYS 372 393 393 LYS LYS C . n 
C 1 373 PRO 373 394 394 PRO PRO C . n 
C 1 374 ILE 374 395 395 ILE ILE C . n 
C 1 375 VAL 375 396 396 VAL VAL C . n 
C 1 376 GLN 376 397 397 GLN GLN C . n 
C 1 377 SER 377 398 398 SER SER C . n 
C 1 378 THR 378 399 399 THR THR C . n 
C 1 379 SER 379 400 400 SER SER C . n 
C 1 380 THR 380 401 401 THR THR C . n 
C 1 381 VAL 381 402 402 VAL VAL C . n 
C 1 382 ILE 382 403 403 ILE ILE C . n 
C 1 383 THR 383 404 404 THR THR C . n 
C 1 384 MET 384 405 405 MET MET C . n 
C 1 385 ILE 385 406 406 ILE ILE C . n 
C 1 386 ASP 386 407 407 ASP ASP C . n 
C 1 387 ASN 387 408 408 ASN ASN C . n 
C 1 388 SER 388 409 409 SER SER C . n 
C 1 389 LYS 389 410 410 LYS LYS C . n 
C 1 390 CYS 390 411 411 CYS CYS C . n 
C 1 391 PRO 391 412 412 PRO PRO C . n 
C 1 392 VAL 392 413 413 VAL VAL C . n 
C 1 393 VAL 393 414 414 VAL VAL C . n 
C 1 394 GLU 394 415 415 GLU GLU C . n 
C 1 395 VAL 395 416 416 VAL VAL C . n 
C 1 396 GLY 396 417 417 GLY GLY C . n 
C 1 397 LYS 397 418 418 LYS LYS C . n 
C 1 398 GLN 398 419 419 GLN GLN C . n 
C 1 399 MET 399 420 420 MET MET C . n 
C 1 400 ILE 400 421 421 ILE ILE C . n 
C 1 401 SER 401 422 422 SER SER C . n 
C 1 402 VAL 402 423 423 VAL VAL C . n 
C 1 403 GLY 403 424 424 GLY GLY C . n 
C 1 404 SER 404 425 425 SER SER C . n 
C 1 405 TYR 405 426 426 TYR TYR C . n 
C 1 406 LEU 406 427 427 LEU LEU C . n 
C 1 407 GLY 407 428 428 GLY GLY C . n 
C 1 408 GLN 408 429 429 GLN GLN C . n 
C 1 409 VAL 409 430 430 VAL VAL C . n 
C 1 410 SER 410 431 431 SER SER C . n 
C 1 411 PRO 411 432 432 PRO PRO C . n 
C 1 412 ASN 412 433 433 ASN ASN C . n 
C 1 413 ASN 413 434 434 ASN ASN C . n 
C 1 414 LEU 414 435 435 LEU LEU C . n 
C 1 415 THR 415 436 436 THR THR C . n 
C 1 416 ILE 416 437 437 ILE ILE C . n 
C 1 417 GLU 417 438 438 GLU GLU C . n 
C 1 418 ILE 418 439 439 ILE ILE C . n 
C 1 419 GLY 419 440 440 GLY GLY C . n 
C 1 420 PRO 420 441 441 PRO PRO C . n 
C 1 421 PRO 421 442 442 PRO PRO C . n 
C 1 422 VAL 422 443 443 VAL VAL C . n 
C 1 423 TYR 423 444 444 TYR TYR C . n 
C 1 424 THR 424 445 445 THR THR C . n 
C 1 425 GLU 425 446 446 GLU GLU C . n 
C 1 426 PRO 426 447 447 PRO PRO C . n 
C 1 427 VAL 427 448 448 VAL VAL C . n 
C 1 428 ASP 428 449 449 ASP ASP C . n 
C 1 429 ILE 429 450 450 ILE ILE C . n 
C 1 430 THR 430 451 451 THR THR C . n 
C 1 431 ASN 431 452 452 ASN ASN C . n 
C 1 432 GLN 432 453 453 GLN GLN C . n 
C 1 433 LEU 433 454 454 LEU LEU C . n 
C 1 434 GLY 434 455 455 GLY GLY C . n 
C 1 435 ASN 435 456 456 ASN ASN C . n 
C 1 436 ILE 436 457 457 ILE ILE C . n 
C 1 437 ASN 437 458 458 ASN ASN C . n 
C 1 438 GLU 438 459 459 GLU GLU C . n 
C 1 439 THR 439 460 460 THR THR C . n 
C 1 440 LEU 440 461 461 LEU LEU C . n 
C 1 441 SER 441 462 462 SER SER C . n 
C 1 442 LYS 442 463 463 LYS LYS C . n 
C 1 443 THR 443 464 464 THR THR C . n 
C 1 444 LEU 444 465 465 LEU LEU C . n 
C 1 445 ASP 445 466 466 ASP ASP C . n 
C 1 446 LEU 446 467 467 LEU LEU C . n 
C 1 447 ILE 447 468 468 ILE ILE C . n 
C 1 448 LYS 448 469 469 LYS LYS C . n 
C 1 449 GLN 449 470 470 GLN GLN C . n 
C 1 450 SER 450 471 471 SER SER C . n 
C 1 451 ASN 451 472 472 ASN ASN C . n 
C 1 452 SER 452 473 473 SER SER C . n 
C 1 453 ILE 453 474 474 ILE ILE C . n 
C 1 454 LEU 454 475 475 LEU LEU C . n 
C 1 455 ASP 455 476 476 ASP ASP C . n 
C 1 456 MET 456 477 477 MET MET C . n 
C 1 457 ILE 457 478 478 ILE ILE C . n 
C 1 458 THR 458 479 479 THR THR C . n 
C 1 459 GLY 459 480 480 GLY GLY C . n 
C 1 460 GLY 460 481 481 GLY GLY C . n 
C 1 461 LEU 461 482 482 LEU LEU C . n 
C 1 462 GLY 462 483 ?   ?   ?   C . n 
C 1 463 SER 463 484 ?   ?   ?   C . n 
C 1 464 GLY 464 485 ?   ?   ?   C . n 
C 1 465 TYR 465 486 ?   ?   ?   C . n 
C 1 466 ILE 466 487 ?   ?   ?   C . n 
C 1 467 PRO 467 488 ?   ?   ?   C . n 
C 1 468 GLU 468 489 ?   ?   ?   C . n 
C 1 469 ALA 469 490 ?   ?   ?   C . n 
C 1 470 PRO 470 491 ?   ?   ?   C . n 
C 1 471 ARG 471 492 ?   ?   ?   C . n 
C 1 472 ASP 472 493 ?   ?   ?   C . n 
C 1 473 GLY 473 494 ?   ?   ?   C . n 
C 1 474 GLN 474 495 ?   ?   ?   C . n 
C 1 475 ALA 475 496 ?   ?   ?   C . n 
C 1 476 TYR 476 497 ?   ?   ?   C . n 
C 1 477 VAL 477 498 ?   ?   ?   C . n 
C 1 478 ARG 478 499 ?   ?   ?   C . n 
C 1 479 LYS 479 500 ?   ?   ?   C . n 
C 1 480 ASP 480 501 ?   ?   ?   C . n 
C 1 481 GLY 481 502 ?   ?   ?   C . n 
C 1 482 GLU 482 503 ?   ?   ?   C . n 
C 1 483 TRP 483 504 ?   ?   ?   C . n 
C 1 484 VAL 484 505 ?   ?   ?   C . n 
C 1 485 LEU 485 506 ?   ?   ?   C . n 
C 1 486 LEU 486 507 ?   ?   ?   C . n 
C 1 487 SER 487 508 ?   ?   ?   C . n 
C 1 488 THR 488 509 ?   ?   ?   C . n 
C 1 489 PHE 489 510 ?   ?   ?   C . n 
C 1 490 LEU 490 511 ?   ?   ?   C . n 
C 1 491 GLY 491 512 ?   ?   ?   C . n 
C 1 492 ARG 492 513 ?   ?   ?   C . n 
C 1 493 SER 493 514 ?   ?   ?   C . n 
C 1 494 LEU 494 515 ?   ?   ?   C . n 
C 1 495 GLU 495 516 ?   ?   ?   C . n 
C 1 496 VAL 496 517 ?   ?   ?   C . n 
C 1 497 LEU 497 518 ?   ?   ?   C . n 
C 1 498 PHE 498 519 ?   ?   ?   C . n 
C 1 499 GLN 499 520 ?   ?   ?   C . n 
C 1 500 GLY 500 521 ?   ?   ?   C . n 
C 1 501 PRO 501 522 ?   ?   ?   C . n 
C 1 502 GLY 502 523 ?   ?   ?   C . n 
C 1 503 HIS 503 524 ?   ?   ?   C . n 
C 1 504 HIS 504 525 ?   ?   ?   C . n 
C 1 505 HIS 505 526 ?   ?   ?   C . n 
C 1 506 HIS 506 527 ?   ?   ?   C . n 
C 1 507 HIS 507 528 ?   ?   ?   C . n 
C 1 508 HIS 508 529 ?   ?   ?   C . n 
C 1 509 HIS 509 530 ?   ?   ?   C . n 
C 1 510 HIS 510 531 ?   ?   ?   C . n 
C 1 511 SER 511 532 ?   ?   ?   C . n 
C 1 512 ALA 512 533 ?   ?   ?   C . n 
C 1 513 TRP 513 534 ?   ?   ?   C . n 
C 1 514 SER 514 535 ?   ?   ?   C . n 
C 1 515 HIS 515 536 ?   ?   ?   C . n 
C 1 516 PRO 516 537 ?   ?   ?   C . n 
C 1 517 GLN 517 538 ?   ?   ?   C . n 
C 1 518 PHE 518 539 ?   ?   ?   C . n 
C 1 519 GLU 519 540 ?   ?   ?   C . n 
C 1 520 LYS 520 541 ?   ?   ?   C . n 
C 1 521 GLY 521 542 ?   ?   ?   C . n 
C 1 522 GLY 522 543 ?   ?   ?   C . n 
C 1 523 GLY 523 544 ?   ?   ?   C . n 
C 1 524 SER 524 545 ?   ?   ?   C . n 
C 1 525 GLY 525 546 ?   ?   ?   C . n 
C 1 526 GLY 526 547 ?   ?   ?   C . n 
C 1 527 GLY 527 548 ?   ?   ?   C . n 
C 1 528 GLY 528 549 ?   ?   ?   C . n 
C 1 529 SER 529 550 ?   ?   ?   C . n 
C 1 530 GLY 530 551 ?   ?   ?   C . n 
C 1 531 GLY 531 552 ?   ?   ?   C . n 
C 1 532 SER 532 553 ?   ?   ?   C . n 
C 1 533 ALA 533 554 ?   ?   ?   C . n 
C 1 534 TRP 534 555 ?   ?   ?   C . n 
C 1 535 SER 535 556 ?   ?   ?   C . n 
C 1 536 HIS 536 557 ?   ?   ?   C . n 
C 1 537 PRO 537 558 ?   ?   ?   C . n 
C 1 538 GLN 538 559 ?   ?   ?   C . n 
C 1 539 PHE 539 560 ?   ?   ?   C . n 
C 1 540 GLU 540 561 ?   ?   ?   C . n 
C 1 541 LYS 541 562 ?   ?   ?   C . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
D 2 NAG 1 D NAG 1 D NAG 1  n 
D 2 NAG 2 D NAG 2 D NAG 9  n 
D 2 BMA 3 D BMA 3 D BMA 10 n 
E 3 NAG 1 E NAG 1 D NAG 2  n 
E 3 NAG 2 E NAG 2 D NAG 3  n 
E 3 BMA 3 E BMA 3 D BMA 4  n 
E 3 FUC 4 E FUC 4 D FUC 5  n 
F 2 NAG 1 F NAG 1 E NAG 1  n 
F 2 NAG 2 F NAG 2 E NAG 9  n 
F 2 BMA 3 F BMA 3 E BMA 10 n 
G 3 NAG 1 G NAG 1 E NAG 2  n 
G 3 NAG 2 G NAG 2 E NAG 3  n 
G 3 BMA 3 G BMA 3 E BMA 4  n 
G 3 FUC 4 G FUC 4 E FUC 5  n 
H 2 NAG 1 H NAG 1 F NAG 1  n 
H 2 NAG 2 H NAG 2 F NAG 9  n 
H 2 BMA 3 H BMA 3 F BMA 10 n 
I 3 NAG 1 I NAG 1 F NAG 2  n 
I 3 NAG 2 I NAG 2 F NAG 3  n 
I 3 BMA 3 I BMA 3 F BMA 4  n 
I 3 FUC 4 I FUC 4 F FUC 5  n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 BMA ? ? BMA ? ? 'SUBJECT OF INVESTIGATION' ? 
2 FUC ? ? FUC ? ? 'SUBJECT OF INVESTIGATION' ? 
3 NAG ? ? NAG ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
J 4 NAG 1 601 6 NAG NAG A . 
K 4 NAG 1 602 7 NAG NAG A . 
L 4 NAG 1 603 8 NAG NAG A . 
M 4 NAG 1 601 6 NAG NAG B . 
N 4 NAG 1 602 7 NAG NAG B . 
O 4 NAG 1 603 8 NAG NAG B . 
P 4 NAG 1 601 6 NAG NAG C . 
Q 4 NAG 1 602 7 NAG NAG C . 
R 4 NAG 1 603 8 NAG NAG C . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9MNH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9MNH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9MNH 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9MNH 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            4.03 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_struct.entry_id                     9MNH 
_struct.title                        'Angavokely virus (AngV) fusion (F) protein ectodomain in pre-fusion conformation' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9MNH 
_struct_keywords.text            
'Henipavirus, AngV-F protein, Pre-fusion F protein, Cryo-EM structure, Fusion Ectodomain, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
P N N 4 ? 
Q N N 4 ? 
R N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9MNH 
_struct_ref.pdbx_db_accession          9MNH 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9MNH A 1 ? 541 ? 9MNH 22 ? 562 ? 22 562 
2 1 9MNH B 1 ? 541 ? 9MNH 22 ? 562 ? 22 562 
3 1 9MNH C 1 ? 541 ? 9MNH 22 ? 562 ? 22 562 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 2   ? GLY A 10  ? ASP A 23  GLY A 31  1 ? 9  
HELX_P HELX_P2  AA2 ASN A 39  ? VAL A 43  ? ASN A 60  VAL A 64  5 ? 5  
HELX_P HELX_P3  AA3 SER A 48  ? VAL A 74  ? SER A 69  VAL A 95  1 ? 27 
HELX_P HELX_P4  AA4 ALA A 89  ? GLY A 94  ? ALA A 110 GLY A 115 1 ? 6  
HELX_P HELX_P5  AA5 THR A 97  ? SER A 119 ? THR A 118 SER A 140 1 ? 23 
HELX_P HELX_P6  AA6 LEU A 120 ? THR A 125 ? LEU A 141 THR A 146 1 ? 6  
HELX_P HELX_P7  AA7 ASP A 150 ? ASN A 155 ? ASP A 171 ASN A 176 1 ? 6  
HELX_P HELX_P8  AA8 SER A 164 ? PHE A 187 ? SER A 185 PHE A 208 1 ? 24 
HELX_P HELX_P9  AA9 GLY A 188 ? ARG A 192 ? GLY A 209 ARG A 213 5 ? 5  
HELX_P HELX_P10 AB1 SER A 200 ? GLN A 206 ? SER A 221 GLN A 227 1 ? 7  
HELX_P HELX_P11 AB2 LEU A 207 ? GLU A 209 ? LEU A 228 GLU A 230 5 ? 3  
HELX_P HELX_P12 AB3 ASN A 211 ? GLY A 220 ? ASN A 232 GLY A 241 1 ? 10 
HELX_P HELX_P13 AB4 PHE A 226 ? THR A 231 ? PHE A 247 THR A 252 1 ? 6  
HELX_P HELX_P14 AB5 ASN A 322 ? GLY A 331 ? ASN A 343 GLY A 352 1 ? 10 
HELX_P HELX_P15 AB6 GLU A 425 ? ILE A 457 ? GLU A 446 ILE A 478 1 ? 33 
HELX_P HELX_P16 AB7 ASP B 2   ? GLY B 10  ? ASP B 23  GLY B 31  1 ? 9  
HELX_P HELX_P17 AB8 ASN B 39  ? VAL B 43  ? ASN B 60  VAL B 64  5 ? 5  
HELX_P HELX_P18 AB9 SER B 48  ? ASN B 73  ? SER B 69  ASN B 94  1 ? 26 
HELX_P HELX_P19 AC1 THR B 97  ? SER B 119 ? THR B 118 SER B 140 1 ? 23 
HELX_P HELX_P20 AC2 LEU B 120 ? THR B 125 ? LEU B 141 THR B 146 1 ? 6  
HELX_P HELX_P21 AC3 SER B 164 ? PHE B 187 ? SER B 185 PHE B 208 1 ? 24 
HELX_P HELX_P22 AC4 GLY B 188 ? ARG B 192 ? GLY B 209 ARG B 213 5 ? 5  
HELX_P HELX_P23 AC5 ILE B 201 ? GLN B 206 ? ILE B 222 GLN B 227 1 ? 6  
HELX_P HELX_P24 AC6 ASN B 211 ? GLY B 220 ? ASN B 232 GLY B 241 1 ? 10 
HELX_P HELX_P25 AC7 PHE B 226 ? THR B 231 ? PHE B 247 THR B 252 1 ? 6  
HELX_P HELX_P26 AC8 ASN B 322 ? GLY B 331 ? ASN B 343 GLY B 352 1 ? 10 
HELX_P HELX_P27 AC9 GLU B 425 ? THR B 458 ? GLU B 446 THR B 479 1 ? 34 
HELX_P HELX_P28 AD1 ASP C 2   ? GLY C 10  ? ASP C 23  GLY C 31  1 ? 9  
HELX_P HELX_P29 AD2 ASN C 39  ? VAL C 43  ? ASN C 60  VAL C 64  5 ? 5  
HELX_P HELX_P30 AD3 SER C 48  ? ARG C 71  ? SER C 69  ARG C 92  1 ? 24 
HELX_P HELX_P31 AD4 GLY C 90  ? GLY C 94  ? GLY C 111 GLY C 115 1 ? 5  
HELX_P HELX_P32 AD5 THR C 97  ? SER C 119 ? THR C 118 SER C 140 1 ? 23 
HELX_P HELX_P33 AD6 LEU C 120 ? THR C 125 ? LEU C 141 THR C 146 1 ? 6  
HELX_P HELX_P34 AD7 ASP C 150 ? ASN C 155 ? ASP C 171 ASN C 176 1 ? 6  
HELX_P HELX_P35 AD8 SER C 164 ? PHE C 187 ? SER C 185 PHE C 208 1 ? 24 
HELX_P HELX_P36 AD9 GLY C 188 ? ARG C 192 ? GLY C 209 ARG C 213 5 ? 5  
HELX_P HELX_P37 AE1 ILE C 201 ? GLN C 206 ? ILE C 222 GLN C 227 1 ? 6  
HELX_P HELX_P38 AE2 ASN C 211 ? GLY C 220 ? ASN C 232 GLY C 241 1 ? 10 
HELX_P HELX_P39 AE3 PHE C 226 ? THR C 231 ? PHE C 247 THR C 252 1 ? 6  
HELX_P HELX_P40 AE4 ASN C 322 ? GLY C 331 ? ASN C 343 GLY C 352 1 ? 10 
HELX_P HELX_P41 AE5 ASN C 332 ? CYS C 336 ? ASN C 353 CYS C 357 5 ? 5  
HELX_P HELX_P42 AE6 VAL C 427 ? THR C 458 ? VAL C 448 THR C 479 1 ? 32 
HELX_P HELX_P43 AE7 GLY C 459 ? LEU C 461 ? GLY C 480 LEU C 482 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 44  SG  ? ? ? 1_555 A CYS 165 SG ? ? A CYS 65  A CYS 186 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf2  disulf ?    ? A CYS 304 SG  ? ? ? 1_555 A CYS 313 SG ? ? A CYS 325 A CYS 334 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf3  disulf ?    ? A CYS 328 SG  ? ? ? 1_555 A CYS 336 SG ? ? A CYS 349 A CYS 357 1_555 ? ? ? ? ? ? ? 2.022 ? ?               
disulf4  disulf ?    ? A CYS 360 SG  ? ? ? 1_555 A CYS 365 SG ? ? A CYS 381 A CYS 386 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf5  disulf ?    ? A CYS 367 SG  ? ? ? 1_555 A CYS 390 SG ? ? A CYS 388 A CYS 411 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf6  disulf ?    ? B CYS 44  SG  ? ? ? 1_555 B CYS 165 SG ? ? B CYS 65  B CYS 186 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf7  disulf ?    ? B CYS 304 SG  ? ? ? 1_555 B CYS 313 SG ? ? B CYS 325 B CYS 334 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
disulf8  disulf ?    ? B CYS 328 SG  ? ? ? 1_555 B CYS 336 SG ? ? B CYS 349 B CYS 357 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf9  disulf ?    ? B CYS 360 SG  ? ? ? 1_555 B CYS 365 SG ? ? B CYS 381 B CYS 386 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf10 disulf ?    ? B CYS 367 SG  ? ? ? 1_555 B CYS 390 SG ? ? B CYS 388 B CYS 411 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf11 disulf ?    ? C CYS 44  SG  ? ? ? 1_555 C CYS 165 SG ? ? C CYS 65  C CYS 186 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf12 disulf ?    ? C CYS 304 SG  ? ? ? 1_555 C CYS 313 SG ? ? C CYS 325 C CYS 334 1_555 ? ? ? ? ? ? ? 2.029 ? ?               
disulf13 disulf ?    ? C CYS 328 SG  ? ? ? 1_555 C CYS 336 SG ? ? C CYS 349 C CYS 357 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf14 disulf ?    ? C CYS 360 SG  ? ? ? 1_555 C CYS 365 SG ? ? C CYS 381 C CYS 386 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf15 disulf ?    ? C CYS 367 SG  ? ? ? 1_555 C CYS 390 SG ? ? C CYS 388 C CYS 411 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
covale1  covale one  ? A ASN 40  ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 61  D NAG 1   1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale2  covale one  ? A ASN 72  ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 93  E NAG 1   1_555 ? ? ? ? ? ? ? 1.449 ? N-Glycosylation 
covale3  covale one  ? A ASN 332 ND2 ? ? ? 1_555 K NAG .   C1 ? ? A ASN 353 A NAG 602 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale4  covale one  ? A ASN 413 ND2 ? ? ? 1_555 J NAG .   C1 ? ? A ASN 434 A NAG 601 1_555 ? ? ? ? ? ? ? 1.446 ? N-Glycosylation 
covale5  covale one  ? A ASN 437 ND2 ? ? ? 1_555 L NAG .   C1 ? ? A ASN 458 A NAG 603 1_555 ? ? ? ? ? ? ? 1.447 ? N-Glycosylation 
covale6  covale one  ? B ASN 40  ND2 ? ? ? 1_555 F NAG .   C1 ? ? B ASN 61  F NAG 1   1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale7  covale one  ? B ASN 72  ND2 ? ? ? 1_555 G NAG .   C1 ? ? B ASN 93  G NAG 1   1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale8  covale one  ? B ASN 332 ND2 ? ? ? 1_555 N NAG .   C1 ? ? B ASN 353 B NAG 602 1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale9  covale one  ? B ASN 413 ND2 ? ? ? 1_555 M NAG .   C1 ? ? B ASN 434 B NAG 601 1_555 ? ? ? ? ? ? ? 1.447 ? N-Glycosylation 
covale10 covale one  ? B ASN 437 ND2 ? ? ? 1_555 O NAG .   C1 ? ? B ASN 458 B NAG 603 1_555 ? ? ? ? ? ? ? 1.434 ? N-Glycosylation 
covale11 covale one  ? C ASN 40  ND2 ? ? ? 1_555 H NAG .   C1 ? ? C ASN 61  H NAG 1   1_555 ? ? ? ? ? ? ? 1.435 ? N-Glycosylation 
covale12 covale one  ? C ASN 72  ND2 ? ? ? 1_555 I NAG .   C1 ? ? C ASN 93  I NAG 1   1_555 ? ? ? ? ? ? ? 1.450 ? N-Glycosylation 
covale13 covale one  ? C ASN 332 ND2 ? ? ? 1_555 Q NAG .   C1 ? ? C ASN 353 C NAG 602 1_555 ? ? ? ? ? ? ? 1.447 ? N-Glycosylation 
covale14 covale one  ? C ASN 413 ND2 ? ? ? 1_555 P NAG .   C1 ? ? C ASN 434 C NAG 601 1_555 ? ? ? ? ? ? ? 1.453 ? N-Glycosylation 
covale15 covale one  ? C ASN 437 ND2 ? ? ? 1_555 R NAG .   C1 ? ? C ASN 458 C NAG 603 1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale16 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.454 ? ?               
covale17 covale both ? D NAG .   O4  ? ? ? 1_555 D BMA .   C1 ? ? D NAG 2   D BMA 3   1_555 ? ? ? ? ? ? ? 1.454 ? ?               
covale18 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? E NAG 1   E NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale19 covale both ? E NAG .   O6  ? ? ? 1_555 E FUC .   C1 ? ? E NAG 1   E FUC 4   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale20 covale both ? E NAG .   O4  ? ? ? 1_555 E BMA .   C1 ? ? E NAG 2   E BMA 3   1_555 ? ? ? ? ? ? ? 1.450 ? ?               
covale21 covale both ? F NAG .   O4  ? ? ? 1_555 F NAG .   C1 ? ? F NAG 1   F NAG 2   1_555 ? ? ? ? ? ? ? 1.455 ? ?               
covale22 covale both ? F NAG .   O4  ? ? ? 1_555 F BMA .   C1 ? ? F NAG 2   F BMA 3   1_555 ? ? ? ? ? ? ? 1.450 ? ?               
covale23 covale both ? G NAG .   O4  ? ? ? 1_555 G NAG .   C1 ? ? G NAG 1   G NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale24 covale both ? G NAG .   O6  ? ? ? 1_555 G FUC .   C1 ? ? G NAG 1   G FUC 4   1_555 ? ? ? ? ? ? ? 1.444 ? ?               
covale25 covale both ? G NAG .   O4  ? ? ? 1_555 G BMA .   C1 ? ? G NAG 2   G BMA 3   1_555 ? ? ? ? ? ? ? 1.446 ? ?               
covale26 covale both ? H NAG .   O4  ? ? ? 1_555 H NAG .   C1 ? ? H NAG 1   H NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale27 covale both ? H NAG .   O4  ? ? ? 1_555 H BMA .   C1 ? ? H NAG 2   H BMA 3   1_555 ? ? ? ? ? ? ? 1.459 ? ?               
covale28 covale both ? I NAG .   O4  ? ? ? 1_555 I NAG .   C1 ? ? I NAG 1   I NAG 2   1_555 ? ? ? ? ? ? ? 1.443 ? ?               
covale29 covale both ? I NAG .   O6  ? ? ? 1_555 I FUC .   C1 ? ? I NAG 1   I FUC 4   1_555 ? ? ? ? ? ? ? 1.445 ? ?               
covale30 covale both ? I NAG .   O4  ? ? ? 1_555 I BMA .   C1 ? ? I NAG 2   I BMA 3   1_555 ? ? ? ? ? ? ? 1.448 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG D .   ? ASN A 40  ? NAG D 1   ? 1_555 ASN A 61  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG E .   ? ASN A 72  ? NAG E 1   ? 1_555 ASN A 93  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG F .   ? ASN B 40  ? NAG F 1   ? 1_555 ASN B 61  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG G .   ? ASN B 72  ? NAG G 1   ? 1_555 ASN B 93  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG H .   ? ASN C 40  ? NAG H 1   ? 1_555 ASN C 61  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  NAG I .   ? ASN C 72  ? NAG I 1   ? 1_555 ASN C 93  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
7  NAG J .   ? ASN A 413 ? NAG A 601 ? 1_555 ASN A 434 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
8  NAG K .   ? ASN A 332 ? NAG A 602 ? 1_555 ASN A 353 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
9  NAG L .   ? ASN A 437 ? NAG A 603 ? 1_555 ASN A 458 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
10 NAG M .   ? ASN B 413 ? NAG B 601 ? 1_555 ASN B 434 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
11 NAG N .   ? ASN B 332 ? NAG B 602 ? 1_555 ASN B 353 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
12 NAG O .   ? ASN B 437 ? NAG B 603 ? 1_555 ASN B 458 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
13 NAG P .   ? ASN C 413 ? NAG C 601 ? 1_555 ASN C 434 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
14 NAG Q .   ? ASN C 332 ? NAG C 602 ? 1_555 ASN C 353 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
15 NAG R .   ? ASN C 437 ? NAG C 603 ? 1_555 ASN C 458 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
16 CYS A 44  ? CYS A 165 ? CYS A 65  ? 1_555 CYS A 186 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
17 CYS A 304 ? CYS A 313 ? CYS A 325 ? 1_555 CYS A 334 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
18 CYS A 328 ? CYS A 336 ? CYS A 349 ? 1_555 CYS A 357 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
19 CYS A 360 ? CYS A 365 ? CYS A 381 ? 1_555 CYS A 386 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
20 CYS A 367 ? CYS A 390 ? CYS A 388 ? 1_555 CYS A 411 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
21 CYS B 44  ? CYS B 165 ? CYS B 65  ? 1_555 CYS B 186 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
22 CYS B 304 ? CYS B 313 ? CYS B 325 ? 1_555 CYS B 334 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
23 CYS B 328 ? CYS B 336 ? CYS B 349 ? 1_555 CYS B 357 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
24 CYS B 360 ? CYS B 365 ? CYS B 381 ? 1_555 CYS B 386 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
25 CYS B 367 ? CYS B 390 ? CYS B 388 ? 1_555 CYS B 411 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
26 CYS C 44  ? CYS C 165 ? CYS C 65  ? 1_555 CYS C 186 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
27 CYS C 304 ? CYS C 313 ? CYS C 325 ? 1_555 CYS C 334 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
28 CYS C 328 ? CYS C 336 ? CYS C 349 ? 1_555 CYS C 357 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
29 CYS C 360 ? CYS C 365 ? CYS C 381 ? 1_555 CYS C 386 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
30 CYS C 367 ? CYS C 390 ? CYS C 388 ? 1_555 CYS C 411 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 3 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 5 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 4 ? 
AB5 ? 2 ? 
AB6 ? 3 ? 
AB7 ? 4 ? 
AB8 ? 5 ? 
AB9 ? 4 ? 
AC1 ? 4 ? 
AC2 ? 2 ? 
AC3 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? parallel      
AA8 5 6 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? parallel      
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB8 4 5 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? parallel      
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 258 ? GLU A 260 ? LEU A 279 GLU A 281 
AA1 2 GLY A 11  ? LYS A 22  ? GLY A 32  LYS A 43  
AA1 3 SER A 310 ? CYS A 313 ? SER A 331 CYS A 334 
AA1 4 ILE A 305 ? ILE A 306 ? ILE A 326 ILE A 327 
AA2 1 LEU A 258 ? GLU A 260 ? LEU A 279 GLU A 281 
AA2 2 GLY A 11  ? LYS A 22  ? GLY A 32  LYS A 43  
AA2 3 VAL A 265 ? LYS A 271 ? VAL A 286 LYS A 292 
AA2 4 ILE A 289 ? ILE A 291 ? ILE A 310 ILE A 312 
AA2 5 LEU A 296 ? ILE A 299 ? LEU A 317 ILE A 320 
AA2 6 SER A 318 ? LEU A 319 ? SER A 339 LEU A 340 
AA3 1 THR A 26  ? LYS A 33  ? THR A 47  LYS A 54  
AA3 2 TYR A 248 ? ILE A 255 ? TYR A 269 ILE A 276 
AA3 3 GLY A 237 ? TRP A 241 ? GLY A 258 TRP A 262 
AA4 1 ILE A 95  ? ALA A 96  ? ILE A 116 ALA A 117 
AA4 2 TYR B 349 ? SER B 352 ? TYR B 370 SER B 373 
AA4 3 VAL B 355 ? ALA B 358 ? VAL B 376 ALA B 379 
AA4 4 THR B 383 ? ILE B 385 ? THR B 404 ILE B 406 
AA5 1 LEU A 134 ? SER A 135 ? LEU A 155 SER A 156 
AA5 2 THR A 141 ? VAL A 142 ? THR A 162 VAL A 163 
AA6 1 TYR A 274 ? PHE A 276 ? TYR A 295 PHE A 297 
AA6 2 SER A 279 ? PRO A 283 ? SER A 300 PRO A 304 
AA6 3 ARG A 338 ? VAL A 341 ? ARG A 359 VAL A 362 
AA7 1 THR A 383 ? ILE A 385 ? THR A 404 ILE A 406 
AA7 2 VAL A 355 ? ALA A 358 ? VAL A 376 ALA A 379 
AA7 3 TYR A 349 ? SER A 352 ? TYR A 370 SER A 373 
AA7 4 ILE C 95  ? ALA C 96  ? ILE C 116 ALA C 117 
AA8 1 LYS A 372 ? PRO A 373 ? LYS A 393 PRO A 394 
AA8 2 CYS A 365 ? CYS A 367 ? CYS A 386 CYS A 388 
AA8 3 VAL A 392 ? VAL A 395 ? VAL A 413 VAL A 416 
AA8 4 GLN A 398 ? SER A 401 ? GLN A 419 SER A 422 
AA8 5 ALA C 86  ? ALA C 89  ? ALA C 107 ALA C 110 
AA8 6 LYS C 75  ? ASP C 76  ? LYS C 96  ASP C 97  
AA9 1 LEU B 258 ? GLU B 260 ? LEU B 279 GLU B 281 
AA9 2 GLY B 11  ? LYS B 22  ? GLY B 32  LYS B 43  
AA9 3 VAL B 265 ? LYS B 271 ? VAL B 286 LYS B 292 
AA9 4 LYS B 288 ? ILE B 291 ? LYS B 309 ILE B 312 
AA9 5 LEU B 296 ? SER B 297 ? LEU B 317 SER B 318 
AB1 1 LEU B 258 ? GLU B 260 ? LEU B 279 GLU B 281 
AB1 2 GLY B 11  ? LYS B 22  ? GLY B 32  LYS B 43  
AB1 3 SER B 310 ? CYS B 313 ? SER B 331 CYS B 334 
AB1 4 ILE B 305 ? ILE B 306 ? ILE B 326 ILE B 327 
AB2 1 THR B 26  ? LYS B 33  ? THR B 47  LYS B 54  
AB2 2 TYR B 248 ? ILE B 255 ? TYR B 269 ILE B 276 
AB2 3 THR B 236 ? TRP B 241 ? THR B 257 TRP B 262 
AB2 4 VAL B 199 ? SER B 200 ? VAL B 220 SER B 221 
AB3 1 VAL B 74  ? LYS B 75  ? VAL B 95  LYS B 96  
AB3 2 ILE B 87  ? ALA B 89  ? ILE B 108 ALA B 110 
AB3 3 GLN C 398 ? SER C 401 ? GLN C 419 SER C 422 
AB3 4 VAL C 392 ? VAL C 395 ? VAL C 413 VAL C 416 
AB3 5 CYS C 365 ? CYS C 367 ? CYS C 386 CYS C 388 
AB3 6 LYS C 372 ? PRO C 373 ? LYS C 393 PRO C 394 
AB4 1 ILE B 95  ? ALA B 96  ? ILE B 116 ALA B 117 
AB4 2 TYR C 349 ? SER C 352 ? TYR C 370 SER C 373 
AB4 3 VAL C 355 ? ALA C 358 ? VAL C 376 ALA C 379 
AB4 4 THR C 383 ? ILE C 385 ? THR C 404 ILE C 406 
AB5 1 LEU B 134 ? SER B 135 ? LEU B 155 SER B 156 
AB5 2 THR B 141 ? VAL B 142 ? THR B 162 VAL B 163 
AB6 1 TYR B 274 ? PHE B 276 ? TYR B 295 PHE B 297 
AB6 2 SER B 279 ? PRO B 283 ? SER B 300 PRO B 304 
AB6 3 ARG B 338 ? VAL B 341 ? ARG B 359 VAL B 362 
AB7 1 LYS B 372 ? PRO B 373 ? LYS B 393 PRO B 394 
AB7 2 CYS B 365 ? CYS B 367 ? CYS B 386 CYS B 388 
AB7 3 VAL B 392 ? VAL B 395 ? VAL B 413 VAL B 416 
AB7 4 GLN B 398 ? SER B 401 ? GLN B 419 SER B 422 
AB8 1 LEU C 258 ? GLU C 260 ? LEU C 279 GLU C 281 
AB8 2 GLY C 11  ? LYS C 22  ? GLY C 32  LYS C 43  
AB8 3 VAL C 265 ? LYS C 271 ? VAL C 286 LYS C 292 
AB8 4 LYS C 288 ? ILE C 291 ? LYS C 309 ILE C 312 
AB8 5 LEU C 296 ? SER C 297 ? LEU C 317 SER C 318 
AB9 1 LEU C 258 ? GLU C 260 ? LEU C 279 GLU C 281 
AB9 2 GLY C 11  ? LYS C 22  ? GLY C 32  LYS C 43  
AB9 3 SER C 310 ? CYS C 313 ? SER C 331 CYS C 334 
AB9 4 ILE C 305 ? ILE C 306 ? ILE C 326 ILE C 327 
AC1 1 THR C 26  ? LYS C 33  ? THR C 47  LYS C 54  
AC1 2 TYR C 248 ? ILE C 255 ? TYR C 269 ILE C 276 
AC1 3 THR C 236 ? TRP C 241 ? THR C 257 TRP C 262 
AC1 4 VAL C 199 ? SER C 200 ? VAL C 220 SER C 221 
AC2 1 LEU C 134 ? SER C 135 ? LEU C 155 SER C 156 
AC2 2 THR C 141 ? VAL C 142 ? THR C 162 VAL C 163 
AC3 1 TYR C 274 ? PHE C 276 ? TYR C 295 PHE C 297 
AC3 2 SER C 279 ? PRO C 283 ? SER C 300 PRO C 304 
AC3 3 ARG C 338 ? VAL C 341 ? ARG C 359 VAL C 362 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 259 ? O ILE A 280 N ILE A 21  ? N ILE A 42  
AA1 2 3 N LYS A 20  ? N LYS A 41  O TYR A 311 ? O TYR A 332 
AA1 3 4 O VAL A 312 ? O VAL A 333 N ILE A 305 ? N ILE A 326 
AA2 1 2 O ILE A 259 ? O ILE A 280 N ILE A 21  ? N ILE A 42  
AA2 2 3 N LYS A 17  ? N LYS A 38  O ILE A 266 ? O ILE A 287 
AA2 3 4 N GLN A 267 ? N GLN A 288 O ILE A 289 ? O ILE A 310 
AA2 4 5 N ILE A 290 ? N ILE A 311 O SER A 297 ? O SER A 318 
AA2 5 6 N LEU A 298 ? N LEU A 319 O LEU A 319 ? O LEU A 340 
AA3 1 2 N ILE A 32  ? N ILE A 53  O LEU A 249 ? O LEU A 270 
AA3 2 3 O ARG A 252 ? O ARG A 273 N SER A 238 ? N SER A 259 
AA4 1 2 N ALA A 96  ? N ALA A 117 O LEU B 351 ? O LEU B 372 
AA4 2 3 N ALA B 350 ? N ALA B 371 O TYR B 357 ? O TYR B 378 
AA4 3 4 N ILE B 356 ? N ILE B 377 O ILE B 385 ? O ILE B 406 
AA5 1 2 N LEU A 134 ? N LEU A 155 O VAL A 142 ? O VAL A 163 
AA6 1 2 N TYR A 274 ? N TYR A 295 O TRP A 281 ? O TRP A 302 
AA6 2 3 N LEU A 280 ? N LEU A 301 O VAL A 341 ? O VAL A 362 
AA7 1 2 O THR A 383 ? O THR A 404 N ALA A 358 ? N ALA A 379 
AA7 2 3 O VAL A 355 ? O VAL A 376 N SER A 352 ? N SER A 373 
AA7 3 4 N LEU A 351 ? N LEU A 372 O ALA C 96  ? O ALA C 117 
AA8 1 2 O LYS A 372 ? O LYS A 393 N CYS A 367 ? N CYS A 388 
AA8 2 3 N LYS A 366 ? N LYS A 387 O GLU A 394 ? O GLU A 415 
AA8 3 4 N VAL A 393 ? N VAL A 414 O ILE A 400 ? O ILE A 421 
AA8 4 5 N SER A 401 ? N SER A 422 O VAL C 88  ? O VAL C 109 
AA8 5 6 O ILE C 87  ? O ILE C 108 N LYS C 75  ? N LYS C 96  
AA9 1 2 O ILE B 259 ? O ILE B 280 N ILE B 21  ? N ILE B 42  
AA9 2 3 N LYS B 17  ? N LYS B 38  O ILE B 266 ? O ILE B 287 
AA9 3 4 N GLN B 267 ? N GLN B 288 O ILE B 289 ? O ILE B 310 
AA9 4 5 N ILE B 290 ? N ILE B 311 O SER B 297 ? O SER B 318 
AB1 1 2 O ILE B 259 ? O ILE B 280 N ILE B 21  ? N ILE B 42  
AB1 2 3 N LYS B 20  ? N LYS B 41  O TYR B 311 ? O TYR B 332 
AB1 3 4 O VAL B 312 ? O VAL B 333 N ILE B 305 ? N ILE B 326 
AB2 1 2 N LYS B 28  ? N LYS B 49  O VAL B 253 ? O VAL B 274 
AB2 2 3 O ARG B 252 ? O ARG B 273 N SER B 238 ? N SER B 259 
AB2 3 4 O GLY B 237 ? O GLY B 258 N VAL B 199 ? N VAL B 220 
AB3 1 2 N LYS B 75  ? N LYS B 96  O ILE B 87  ? O ILE B 108 
AB3 2 3 N VAL B 88  ? N VAL B 109 O SER C 401 ? O SER C 422 
AB3 3 4 O ILE C 400 ? O ILE C 421 N VAL C 393 ? N VAL C 414 
AB3 4 5 O GLU C 394 ? O GLU C 415 N LYS C 366 ? N LYS C 387 
AB3 5 6 N CYS C 367 ? N CYS C 388 O LYS C 372 ? O LYS C 393 
AB4 1 2 N ALA B 96  ? N ALA B 117 O LEU C 351 ? O LEU C 372 
AB4 2 3 N ALA C 350 ? N ALA C 371 O TYR C 357 ? O TYR C 378 
AB4 3 4 N ALA C 358 ? N ALA C 379 O THR C 383 ? O THR C 404 
AB5 1 2 N LEU B 134 ? N LEU B 155 O VAL B 142 ? O VAL B 163 
AB6 1 2 N TYR B 274 ? N TYR B 295 O TRP B 281 ? O TRP B 302 
AB6 2 3 N LEU B 280 ? N LEU B 301 O VAL B 341 ? O VAL B 362 
AB7 1 2 O LYS B 372 ? O LYS B 393 N CYS B 367 ? N CYS B 388 
AB7 2 3 N LYS B 366 ? N LYS B 387 O GLU B 394 ? O GLU B 415 
AB7 3 4 N VAL B 393 ? N VAL B 414 O ILE B 400 ? O ILE B 421 
AB8 1 2 O ILE C 259 ? O ILE C 280 N ILE C 21  ? N ILE C 42  
AB8 2 3 N LYS C 17  ? N LYS C 38  O ILE C 266 ? O ILE C 287 
AB8 3 4 N VAL C 265 ? N VAL C 286 O ILE C 291 ? O ILE C 312 
AB8 4 5 N ILE C 290 ? N ILE C 311 O SER C 297 ? O SER C 318 
AB9 1 2 O ILE C 259 ? O ILE C 280 N ILE C 21  ? N ILE C 42  
AB9 2 3 N LYS C 20  ? N LYS C 41  O TYR C 311 ? O TYR C 332 
AB9 3 4 O VAL C 312 ? O VAL C 333 N ILE C 305 ? N ILE C 326 
AC1 1 2 N LYS C 28  ? N LYS C 49  O VAL C 253 ? O VAL C 274 
AC1 2 3 O ARG C 252 ? O ARG C 273 N SER C 238 ? N SER C 259 
AC1 3 4 O GLY C 237 ? O GLY C 258 N VAL C 199 ? N VAL C 220 
AC2 1 2 N LEU C 134 ? N LEU C 155 O VAL C 142 ? O VAL C 163 
AC3 1 2 N TYR C 274 ? N TYR C 295 O TRP C 281 ? O TRP C 302 
AC3 2 3 N LEU C 280 ? N LEU C 301 O VAL C 341 ? O VAL C 362 
# 
_pdbx_entry_details.entry_id                   9MNH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA  A LEU 461 ? ? CB A LEU 461 ? ? CG  A LEU 461 ? ? 129.17 115.30 13.87  2.30 N 
2 1 CG1 B ILE 173 ? ? CB B ILE 173 ? ? CG2 B ILE 173 ? ? 96.77  111.40 -14.63 2.20 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 45  ? ? 52.51   75.40   
2  1 GLU A 67  ? ? 57.27   -149.32 
3  1 ASN A 101 ? ? 50.83   -130.92 
4  1 ALA A 107 ? ? 55.36   -127.02 
5  1 ILE A 108 ? ? 64.81   106.41  
6  1 LYS A 180 ? ? -95.92  59.20   
7  1 PHE A 208 ? ? -93.27  51.57   
8  1 PRO A 215 ? ? -84.25  42.47   
9  1 THR A 257 ? ? 56.08   -172.27 
10 1 SER A 322 ? ? -95.30  56.92   
11 1 TYR A 366 ? ? -92.25  50.08   
12 1 ASP A 407 ? ? -129.96 -168.19 
13 1 SER A 425 ? ? 58.43   -139.52 
14 1 GLN A 429 ? ? 55.13   -96.86  
15 1 HIS B 45  ? ? 52.36   75.85   
16 1 GLU B 67  ? ? 56.95   -143.04 
17 1 ASN B 101 ? ? 29.26   -117.06 
18 1 PHE B 105 ? ? -161.12 -162.34 
19 1 ALA B 107 ? ? 59.07   70.53   
20 1 LYS B 180 ? ? -96.27  58.30   
21 1 PHE B 208 ? ? -93.31  51.25   
22 1 PRO B 215 ? ? -80.17  44.32   
23 1 SER B 322 ? ? -96.23  56.51   
24 1 TYR B 366 ? ? -93.23  51.14   
25 1 SER B 425 ? ? 58.69   -141.46 
26 1 GLN B 429 ? ? 55.46   -95.84  
27 1 THR B 445 ? ? -120.10 -50.72  
28 1 GLU C 67  ? ? 56.95   -148.59 
29 1 ASN C 103 ? ? -109.03 -60.03  
30 1 LYS C 180 ? ? -96.40  51.98   
31 1 PHE C 208 ? ? -92.94  51.50   
32 1 PRO C 215 ? ? -84.34  43.00   
33 1 SER C 322 ? ? -96.48  57.08   
34 1 TYR C 366 ? ? -92.95  49.63   
35 1 SER C 425 ? ? 59.39   -151.89 
36 1 GLN C 429 ? ? -123.92 -55.11  
# 
loop_
_pdbx_validate_main_chain_plane.id 
_pdbx_validate_main_chain_plane.PDB_model_num 
_pdbx_validate_main_chain_plane.auth_comp_id 
_pdbx_validate_main_chain_plane.auth_asym_id 
_pdbx_validate_main_chain_plane.auth_seq_id 
_pdbx_validate_main_chain_plane.PDB_ins_code 
_pdbx_validate_main_chain_plane.label_alt_id 
_pdbx_validate_main_chain_plane.improper_torsion_angle 
1 1 SER A 462 ? ? -11.69 
2 1 SER B 462 ? ? -11.27 
3 1 SER C 462 ? ? -13.44 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9MNH 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 . . . ? A 22-482 SwissModel 'in silico model' ? ? 
2 1 . . . ? B 22-482 SwissModel 'in silico model' ? ? 
3 1 . . . ? C 22-482 SwissModel 'in silico model' ? ? 
# 
_em_3d_reconstruction.entry_id                    9MNH 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     'Non-uniform refinement used for the final reconstruction' 
_em_3d_reconstruction.resolution                  4.03 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               1106722 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          63 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'AngV-F protein trimer in pre-fusion conformation' 
_em_entity_assembly.details              
;AngV-F fusion ectodomain is expressed with following domains at C-terminus, foldon trimerization domain, HRV3C protease site, His-tag, and two streptavidin tags separated by GS linker
;
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_image_scans.entry_id                9MNH 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4092 
_em_image_scans.dimension_width         5760 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9MNH 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         'Grid screening was performed manually' 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1700 
_em_imaging.nominal_defocus_max             2800 
_em_imaging.calibrated_defocus_min          1700 
_em_imaging.calibrated_defocus_max          2800 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           81000 
_em_imaging.calibrated_magnification        81000 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9MNH 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   298 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               
;Protein sample was applied to the grid and incubated for 30 seconds at >95% humidity. Excess protein was blotted away for 2.5 seconds before being plunge frozen into liquid ethane
;
# 
_em_experiment.entry_id                9MNH 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9MNH 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 483 ? A GLY 462 
2   1 Y 1 A SER 484 ? A SER 463 
3   1 Y 1 A GLY 485 ? A GLY 464 
4   1 Y 1 A TYR 486 ? A TYR 465 
5   1 Y 1 A ILE 487 ? A ILE 466 
6   1 Y 1 A PRO 488 ? A PRO 467 
7   1 Y 1 A GLU 489 ? A GLU 468 
8   1 Y 1 A ALA 490 ? A ALA 469 
9   1 Y 1 A PRO 491 ? A PRO 470 
10  1 Y 1 A ARG 492 ? A ARG 471 
11  1 Y 1 A ASP 493 ? A ASP 472 
12  1 Y 1 A GLY 494 ? A GLY 473 
13  1 Y 1 A GLN 495 ? A GLN 474 
14  1 Y 1 A ALA 496 ? A ALA 475 
15  1 Y 1 A TYR 497 ? A TYR 476 
16  1 Y 1 A VAL 498 ? A VAL 477 
17  1 Y 1 A ARG 499 ? A ARG 478 
18  1 Y 1 A LYS 500 ? A LYS 479 
19  1 Y 1 A ASP 501 ? A ASP 480 
20  1 Y 1 A GLY 502 ? A GLY 481 
21  1 Y 1 A GLU 503 ? A GLU 482 
22  1 Y 1 A TRP 504 ? A TRP 483 
23  1 Y 1 A VAL 505 ? A VAL 484 
24  1 Y 1 A LEU 506 ? A LEU 485 
25  1 Y 1 A LEU 507 ? A LEU 486 
26  1 Y 1 A SER 508 ? A SER 487 
27  1 Y 1 A THR 509 ? A THR 488 
28  1 Y 1 A PHE 510 ? A PHE 489 
29  1 Y 1 A LEU 511 ? A LEU 490 
30  1 Y 1 A GLY 512 ? A GLY 491 
31  1 Y 1 A ARG 513 ? A ARG 492 
32  1 Y 1 A SER 514 ? A SER 493 
33  1 Y 1 A LEU 515 ? A LEU 494 
34  1 Y 1 A GLU 516 ? A GLU 495 
35  1 Y 1 A VAL 517 ? A VAL 496 
36  1 Y 1 A LEU 518 ? A LEU 497 
37  1 Y 1 A PHE 519 ? A PHE 498 
38  1 Y 1 A GLN 520 ? A GLN 499 
39  1 Y 1 A GLY 521 ? A GLY 500 
40  1 Y 1 A PRO 522 ? A PRO 501 
41  1 Y 1 A GLY 523 ? A GLY 502 
42  1 Y 1 A HIS 524 ? A HIS 503 
43  1 Y 1 A HIS 525 ? A HIS 504 
44  1 Y 1 A HIS 526 ? A HIS 505 
45  1 Y 1 A HIS 527 ? A HIS 506 
46  1 Y 1 A HIS 528 ? A HIS 507 
47  1 Y 1 A HIS 529 ? A HIS 508 
48  1 Y 1 A HIS 530 ? A HIS 509 
49  1 Y 1 A HIS 531 ? A HIS 510 
50  1 Y 1 A SER 532 ? A SER 511 
51  1 Y 1 A ALA 533 ? A ALA 512 
52  1 Y 1 A TRP 534 ? A TRP 513 
53  1 Y 1 A SER 535 ? A SER 514 
54  1 Y 1 A HIS 536 ? A HIS 515 
55  1 Y 1 A PRO 537 ? A PRO 516 
56  1 Y 1 A GLN 538 ? A GLN 517 
57  1 Y 1 A PHE 539 ? A PHE 518 
58  1 Y 1 A GLU 540 ? A GLU 519 
59  1 Y 1 A LYS 541 ? A LYS 520 
60  1 Y 1 A GLY 542 ? A GLY 521 
61  1 Y 1 A GLY 543 ? A GLY 522 
62  1 Y 1 A GLY 544 ? A GLY 523 
63  1 Y 1 A SER 545 ? A SER 524 
64  1 Y 1 A GLY 546 ? A GLY 525 
65  1 Y 1 A GLY 547 ? A GLY 526 
66  1 Y 1 A GLY 548 ? A GLY 527 
67  1 Y 1 A GLY 549 ? A GLY 528 
68  1 Y 1 A SER 550 ? A SER 529 
69  1 Y 1 A GLY 551 ? A GLY 530 
70  1 Y 1 A GLY 552 ? A GLY 531 
71  1 Y 1 A SER 553 ? A SER 532 
72  1 Y 1 A ALA 554 ? A ALA 533 
73  1 Y 1 A TRP 555 ? A TRP 534 
74  1 Y 1 A SER 556 ? A SER 535 
75  1 Y 1 A HIS 557 ? A HIS 536 
76  1 Y 1 A PRO 558 ? A PRO 537 
77  1 Y 1 A GLN 559 ? A GLN 538 
78  1 Y 1 A PHE 560 ? A PHE 539 
79  1 Y 1 A GLU 561 ? A GLU 540 
80  1 Y 1 A LYS 562 ? A LYS 541 
81  1 Y 1 B GLY 483 ? B GLY 462 
82  1 Y 1 B SER 484 ? B SER 463 
83  1 Y 1 B GLY 485 ? B GLY 464 
84  1 Y 1 B TYR 486 ? B TYR 465 
85  1 Y 1 B ILE 487 ? B ILE 466 
86  1 Y 1 B PRO 488 ? B PRO 467 
87  1 Y 1 B GLU 489 ? B GLU 468 
88  1 Y 1 B ALA 490 ? B ALA 469 
89  1 Y 1 B PRO 491 ? B PRO 470 
90  1 Y 1 B ARG 492 ? B ARG 471 
91  1 Y 1 B ASP 493 ? B ASP 472 
92  1 Y 1 B GLY 494 ? B GLY 473 
93  1 Y 1 B GLN 495 ? B GLN 474 
94  1 Y 1 B ALA 496 ? B ALA 475 
95  1 Y 1 B TYR 497 ? B TYR 476 
96  1 Y 1 B VAL 498 ? B VAL 477 
97  1 Y 1 B ARG 499 ? B ARG 478 
98  1 Y 1 B LYS 500 ? B LYS 479 
99  1 Y 1 B ASP 501 ? B ASP 480 
100 1 Y 1 B GLY 502 ? B GLY 481 
101 1 Y 1 B GLU 503 ? B GLU 482 
102 1 Y 1 B TRP 504 ? B TRP 483 
103 1 Y 1 B VAL 505 ? B VAL 484 
104 1 Y 1 B LEU 506 ? B LEU 485 
105 1 Y 1 B LEU 507 ? B LEU 486 
106 1 Y 1 B SER 508 ? B SER 487 
107 1 Y 1 B THR 509 ? B THR 488 
108 1 Y 1 B PHE 510 ? B PHE 489 
109 1 Y 1 B LEU 511 ? B LEU 490 
110 1 Y 1 B GLY 512 ? B GLY 491 
111 1 Y 1 B ARG 513 ? B ARG 492 
112 1 Y 1 B SER 514 ? B SER 493 
113 1 Y 1 B LEU 515 ? B LEU 494 
114 1 Y 1 B GLU 516 ? B GLU 495 
115 1 Y 1 B VAL 517 ? B VAL 496 
116 1 Y 1 B LEU 518 ? B LEU 497 
117 1 Y 1 B PHE 519 ? B PHE 498 
118 1 Y 1 B GLN 520 ? B GLN 499 
119 1 Y 1 B GLY 521 ? B GLY 500 
120 1 Y 1 B PRO 522 ? B PRO 501 
121 1 Y 1 B GLY 523 ? B GLY 502 
122 1 Y 1 B HIS 524 ? B HIS 503 
123 1 Y 1 B HIS 525 ? B HIS 504 
124 1 Y 1 B HIS 526 ? B HIS 505 
125 1 Y 1 B HIS 527 ? B HIS 506 
126 1 Y 1 B HIS 528 ? B HIS 507 
127 1 Y 1 B HIS 529 ? B HIS 508 
128 1 Y 1 B HIS 530 ? B HIS 509 
129 1 Y 1 B HIS 531 ? B HIS 510 
130 1 Y 1 B SER 532 ? B SER 511 
131 1 Y 1 B ALA 533 ? B ALA 512 
132 1 Y 1 B TRP 534 ? B TRP 513 
133 1 Y 1 B SER 535 ? B SER 514 
134 1 Y 1 B HIS 536 ? B HIS 515 
135 1 Y 1 B PRO 537 ? B PRO 516 
136 1 Y 1 B GLN 538 ? B GLN 517 
137 1 Y 1 B PHE 539 ? B PHE 518 
138 1 Y 1 B GLU 540 ? B GLU 519 
139 1 Y 1 B LYS 541 ? B LYS 520 
140 1 Y 1 B GLY 542 ? B GLY 521 
141 1 Y 1 B GLY 543 ? B GLY 522 
142 1 Y 1 B GLY 544 ? B GLY 523 
143 1 Y 1 B SER 545 ? B SER 524 
144 1 Y 1 B GLY 546 ? B GLY 525 
145 1 Y 1 B GLY 547 ? B GLY 526 
146 1 Y 1 B GLY 548 ? B GLY 527 
147 1 Y 1 B GLY 549 ? B GLY 528 
148 1 Y 1 B SER 550 ? B SER 529 
149 1 Y 1 B GLY 551 ? B GLY 530 
150 1 Y 1 B GLY 552 ? B GLY 531 
151 1 Y 1 B SER 553 ? B SER 532 
152 1 Y 1 B ALA 554 ? B ALA 533 
153 1 Y 1 B TRP 555 ? B TRP 534 
154 1 Y 1 B SER 556 ? B SER 535 
155 1 Y 1 B HIS 557 ? B HIS 536 
156 1 Y 1 B PRO 558 ? B PRO 537 
157 1 Y 1 B GLN 559 ? B GLN 538 
158 1 Y 1 B PHE 560 ? B PHE 539 
159 1 Y 1 B GLU 561 ? B GLU 540 
160 1 Y 1 B LYS 562 ? B LYS 541 
161 1 Y 1 C GLY 483 ? C GLY 462 
162 1 Y 1 C SER 484 ? C SER 463 
163 1 Y 1 C GLY 485 ? C GLY 464 
164 1 Y 1 C TYR 486 ? C TYR 465 
165 1 Y 1 C ILE 487 ? C ILE 466 
166 1 Y 1 C PRO 488 ? C PRO 467 
167 1 Y 1 C GLU 489 ? C GLU 468 
168 1 Y 1 C ALA 490 ? C ALA 469 
169 1 Y 1 C PRO 491 ? C PRO 470 
170 1 Y 1 C ARG 492 ? C ARG 471 
171 1 Y 1 C ASP 493 ? C ASP 472 
172 1 Y 1 C GLY 494 ? C GLY 473 
173 1 Y 1 C GLN 495 ? C GLN 474 
174 1 Y 1 C ALA 496 ? C ALA 475 
175 1 Y 1 C TYR 497 ? C TYR 476 
176 1 Y 1 C VAL 498 ? C VAL 477 
177 1 Y 1 C ARG 499 ? C ARG 478 
178 1 Y 1 C LYS 500 ? C LYS 479 
179 1 Y 1 C ASP 501 ? C ASP 480 
180 1 Y 1 C GLY 502 ? C GLY 481 
181 1 Y 1 C GLU 503 ? C GLU 482 
182 1 Y 1 C TRP 504 ? C TRP 483 
183 1 Y 1 C VAL 505 ? C VAL 484 
184 1 Y 1 C LEU 506 ? C LEU 485 
185 1 Y 1 C LEU 507 ? C LEU 486 
186 1 Y 1 C SER 508 ? C SER 487 
187 1 Y 1 C THR 509 ? C THR 488 
188 1 Y 1 C PHE 510 ? C PHE 489 
189 1 Y 1 C LEU 511 ? C LEU 490 
190 1 Y 1 C GLY 512 ? C GLY 491 
191 1 Y 1 C ARG 513 ? C ARG 492 
192 1 Y 1 C SER 514 ? C SER 493 
193 1 Y 1 C LEU 515 ? C LEU 494 
194 1 Y 1 C GLU 516 ? C GLU 495 
195 1 Y 1 C VAL 517 ? C VAL 496 
196 1 Y 1 C LEU 518 ? C LEU 497 
197 1 Y 1 C PHE 519 ? C PHE 498 
198 1 Y 1 C GLN 520 ? C GLN 499 
199 1 Y 1 C GLY 521 ? C GLY 500 
200 1 Y 1 C PRO 522 ? C PRO 501 
201 1 Y 1 C GLY 523 ? C GLY 502 
202 1 Y 1 C HIS 524 ? C HIS 503 
203 1 Y 1 C HIS 525 ? C HIS 504 
204 1 Y 1 C HIS 526 ? C HIS 505 
205 1 Y 1 C HIS 527 ? C HIS 506 
206 1 Y 1 C HIS 528 ? C HIS 507 
207 1 Y 1 C HIS 529 ? C HIS 508 
208 1 Y 1 C HIS 530 ? C HIS 509 
209 1 Y 1 C HIS 531 ? C HIS 510 
210 1 Y 1 C SER 532 ? C SER 511 
211 1 Y 1 C ALA 533 ? C ALA 512 
212 1 Y 1 C TRP 534 ? C TRP 513 
213 1 Y 1 C SER 535 ? C SER 514 
214 1 Y 1 C HIS 536 ? C HIS 515 
215 1 Y 1 C PRO 537 ? C PRO 516 
216 1 Y 1 C GLN 538 ? C GLN 517 
217 1 Y 1 C PHE 539 ? C PHE 518 
218 1 Y 1 C GLU 540 ? C GLU 519 
219 1 Y 1 C LYS 541 ? C LYS 520 
220 1 Y 1 C GLY 542 ? C GLY 521 
221 1 Y 1 C GLY 543 ? C GLY 522 
222 1 Y 1 C GLY 544 ? C GLY 523 
223 1 Y 1 C SER 545 ? C SER 524 
224 1 Y 1 C GLY 546 ? C GLY 525 
225 1 Y 1 C GLY 547 ? C GLY 526 
226 1 Y 1 C GLY 548 ? C GLY 527 
227 1 Y 1 C GLY 549 ? C GLY 528 
228 1 Y 1 C SER 550 ? C SER 529 
229 1 Y 1 C GLY 551 ? C GLY 530 
230 1 Y 1 C GLY 552 ? C GLY 531 
231 1 Y 1 C SER 553 ? C SER 532 
232 1 Y 1 C ALA 554 ? C ALA 533 
233 1 Y 1 C TRP 555 ? C TRP 534 
234 1 Y 1 C SER 556 ? C SER 535 
235 1 Y 1 C HIS 557 ? C HIS 536 
236 1 Y 1 C PRO 558 ? C PRO 537 
237 1 Y 1 C GLN 559 ? C GLN 538 
238 1 Y 1 C PHE 560 ? C PHE 539 
239 1 Y 1 C GLU 561 ? C GLU 540 
240 1 Y 1 C LYS 562 ? C LYS 541 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BMA C1   C N R 74  
BMA C2   C N S 75  
BMA C3   C N S 76  
BMA C4   C N S 77  
BMA C5   C N R 78  
BMA C6   C N N 79  
BMA O1   O N N 80  
BMA O2   O N N 81  
BMA O3   O N N 82  
BMA O4   O N N 83  
BMA O5   O N N 84  
BMA O6   O N N 85  
BMA H1   H N N 86  
BMA H2   H N N 87  
BMA H3   H N N 88  
BMA H4   H N N 89  
BMA H5   H N N 90  
BMA H61  H N N 91  
BMA H62  H N N 92  
BMA HO1  H N N 93  
BMA HO2  H N N 94  
BMA HO3  H N N 95  
BMA HO4  H N N 96  
BMA HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
FUC C1   C N R 112 
FUC C2   C N S 113 
FUC C3   C N R 114 
FUC C4   C N S 115 
FUC C5   C N S 116 
FUC C6   C N N 117 
FUC O1   O N N 118 
FUC O2   O N N 119 
FUC O3   O N N 120 
FUC O4   O N N 121 
FUC O5   O N N 122 
FUC H1   H N N 123 
FUC H2   H N N 124 
FUC H3   H N N 125 
FUC H4   H N N 126 
FUC H5   H N N 127 
FUC H61  H N N 128 
FUC H62  H N N 129 
FUC H63  H N N 130 
FUC HO1  H N N 131 
FUC HO2  H N N 132 
FUC HO3  H N N 133 
FUC HO4  H N N 134 
GLN N    N N N 135 
GLN CA   C N S 136 
GLN C    C N N 137 
GLN O    O N N 138 
GLN CB   C N N 139 
GLN CG   C N N 140 
GLN CD   C N N 141 
GLN OE1  O N N 142 
GLN NE2  N N N 143 
GLN OXT  O N N 144 
GLN H    H N N 145 
GLN H2   H N N 146 
GLN HA   H N N 147 
GLN HB2  H N N 148 
GLN HB3  H N N 149 
GLN HG2  H N N 150 
GLN HG3  H N N 151 
GLN HE21 H N N 152 
GLN HE22 H N N 153 
GLN HXT  H N N 154 
GLU N    N N N 155 
GLU CA   C N S 156 
GLU C    C N N 157 
GLU O    O N N 158 
GLU CB   C N N 159 
GLU CG   C N N 160 
GLU CD   C N N 161 
GLU OE1  O N N 162 
GLU OE2  O N N 163 
GLU OXT  O N N 164 
GLU H    H N N 165 
GLU H2   H N N 166 
GLU HA   H N N 167 
GLU HB2  H N N 168 
GLU HB3  H N N 169 
GLU HG2  H N N 170 
GLU HG3  H N N 171 
GLU HE2  H N N 172 
GLU HXT  H N N 173 
GLY N    N N N 174 
GLY CA   C N N 175 
GLY C    C N N 176 
GLY O    O N N 177 
GLY OXT  O N N 178 
GLY H    H N N 179 
GLY H2   H N N 180 
GLY HA2  H N N 181 
GLY HA3  H N N 182 
GLY HXT  H N N 183 
HIS N    N N N 184 
HIS CA   C N S 185 
HIS C    C N N 186 
HIS O    O N N 187 
HIS CB   C N N 188 
HIS CG   C Y N 189 
HIS ND1  N Y N 190 
HIS CD2  C Y N 191 
HIS CE1  C Y N 192 
HIS NE2  N Y N 193 
HIS OXT  O N N 194 
HIS H    H N N 195 
HIS H2   H N N 196 
HIS HA   H N N 197 
HIS HB2  H N N 198 
HIS HB3  H N N 199 
HIS HD1  H N N 200 
HIS HD2  H N N 201 
HIS HE1  H N N 202 
HIS HE2  H N N 203 
HIS HXT  H N N 204 
ILE N    N N N 205 
ILE CA   C N S 206 
ILE C    C N N 207 
ILE O    O N N 208 
ILE CB   C N S 209 
ILE CG1  C N N 210 
ILE CG2  C N N 211 
ILE CD1  C N N 212 
ILE OXT  O N N 213 
ILE H    H N N 214 
ILE H2   H N N 215 
ILE HA   H N N 216 
ILE HB   H N N 217 
ILE HG12 H N N 218 
ILE HG13 H N N 219 
ILE HG21 H N N 220 
ILE HG22 H N N 221 
ILE HG23 H N N 222 
ILE HD11 H N N 223 
ILE HD12 H N N 224 
ILE HD13 H N N 225 
ILE HXT  H N N 226 
LEU N    N N N 227 
LEU CA   C N S 228 
LEU C    C N N 229 
LEU O    O N N 230 
LEU CB   C N N 231 
LEU CG   C N N 232 
LEU CD1  C N N 233 
LEU CD2  C N N 234 
LEU OXT  O N N 235 
LEU H    H N N 236 
LEU H2   H N N 237 
LEU HA   H N N 238 
LEU HB2  H N N 239 
LEU HB3  H N N 240 
LEU HG   H N N 241 
LEU HD11 H N N 242 
LEU HD12 H N N 243 
LEU HD13 H N N 244 
LEU HD21 H N N 245 
LEU HD22 H N N 246 
LEU HD23 H N N 247 
LEU HXT  H N N 248 
LYS N    N N N 249 
LYS CA   C N S 250 
LYS C    C N N 251 
LYS O    O N N 252 
LYS CB   C N N 253 
LYS CG   C N N 254 
LYS CD   C N N 255 
LYS CE   C N N 256 
LYS NZ   N N N 257 
LYS OXT  O N N 258 
LYS H    H N N 259 
LYS H2   H N N 260 
LYS HA   H N N 261 
LYS HB2  H N N 262 
LYS HB3  H N N 263 
LYS HG2  H N N 264 
LYS HG3  H N N 265 
LYS HD2  H N N 266 
LYS HD3  H N N 267 
LYS HE2  H N N 268 
LYS HE3  H N N 269 
LYS HZ1  H N N 270 
LYS HZ2  H N N 271 
LYS HZ3  H N N 272 
LYS HXT  H N N 273 
MET N    N N N 274 
MET CA   C N S 275 
MET C    C N N 276 
MET O    O N N 277 
MET CB   C N N 278 
MET CG   C N N 279 
MET SD   S N N 280 
MET CE   C N N 281 
MET OXT  O N N 282 
MET H    H N N 283 
MET H2   H N N 284 
MET HA   H N N 285 
MET HB2  H N N 286 
MET HB3  H N N 287 
MET HG2  H N N 288 
MET HG3  H N N 289 
MET HE1  H N N 290 
MET HE2  H N N 291 
MET HE3  H N N 292 
MET HXT  H N N 293 
NAG C1   C N R 294 
NAG C2   C N R 295 
NAG C3   C N R 296 
NAG C4   C N S 297 
NAG C5   C N R 298 
NAG C6   C N N 299 
NAG C7   C N N 300 
NAG C8   C N N 301 
NAG N2   N N N 302 
NAG O1   O N N 303 
NAG O3   O N N 304 
NAG O4   O N N 305 
NAG O5   O N N 306 
NAG O6   O N N 307 
NAG O7   O N N 308 
NAG H1   H N N 309 
NAG H2   H N N 310 
NAG H3   H N N 311 
NAG H4   H N N 312 
NAG H5   H N N 313 
NAG H61  H N N 314 
NAG H62  H N N 315 
NAG H81  H N N 316 
NAG H82  H N N 317 
NAG H83  H N N 318 
NAG HN2  H N N 319 
NAG HO1  H N N 320 
NAG HO3  H N N 321 
NAG HO4  H N N 322 
NAG HO6  H N N 323 
PHE N    N N N 324 
PHE CA   C N S 325 
PHE C    C N N 326 
PHE O    O N N 327 
PHE CB   C N N 328 
PHE CG   C Y N 329 
PHE CD1  C Y N 330 
PHE CD2  C Y N 331 
PHE CE1  C Y N 332 
PHE CE2  C Y N 333 
PHE CZ   C Y N 334 
PHE OXT  O N N 335 
PHE H    H N N 336 
PHE H2   H N N 337 
PHE HA   H N N 338 
PHE HB2  H N N 339 
PHE HB3  H N N 340 
PHE HD1  H N N 341 
PHE HD2  H N N 342 
PHE HE1  H N N 343 
PHE HE2  H N N 344 
PHE HZ   H N N 345 
PHE HXT  H N N 346 
PRO N    N N N 347 
PRO CA   C N S 348 
PRO C    C N N 349 
PRO O    O N N 350 
PRO CB   C N N 351 
PRO CG   C N N 352 
PRO CD   C N N 353 
PRO OXT  O N N 354 
PRO H    H N N 355 
PRO HA   H N N 356 
PRO HB2  H N N 357 
PRO HB3  H N N 358 
PRO HG2  H N N 359 
PRO HG3  H N N 360 
PRO HD2  H N N 361 
PRO HD3  H N N 362 
PRO HXT  H N N 363 
SER N    N N N 364 
SER CA   C N S 365 
SER C    C N N 366 
SER O    O N N 367 
SER CB   C N N 368 
SER OG   O N N 369 
SER OXT  O N N 370 
SER H    H N N 371 
SER H2   H N N 372 
SER HA   H N N 373 
SER HB2  H N N 374 
SER HB3  H N N 375 
SER HG   H N N 376 
SER HXT  H N N 377 
THR N    N N N 378 
THR CA   C N S 379 
THR C    C N N 380 
THR O    O N N 381 
THR CB   C N R 382 
THR OG1  O N N 383 
THR CG2  C N N 384 
THR OXT  O N N 385 
THR H    H N N 386 
THR H2   H N N 387 
THR HA   H N N 388 
THR HB   H N N 389 
THR HG1  H N N 390 
THR HG21 H N N 391 
THR HG22 H N N 392 
THR HG23 H N N 393 
THR HXT  H N N 394 
TRP N    N N N 395 
TRP CA   C N S 396 
TRP C    C N N 397 
TRP O    O N N 398 
TRP CB   C N N 399 
TRP CG   C Y N 400 
TRP CD1  C Y N 401 
TRP CD2  C Y N 402 
TRP NE1  N Y N 403 
TRP CE2  C Y N 404 
TRP CE3  C Y N 405 
TRP CZ2  C Y N 406 
TRP CZ3  C Y N 407 
TRP CH2  C Y N 408 
TRP OXT  O N N 409 
TRP H    H N N 410 
TRP H2   H N N 411 
TRP HA   H N N 412 
TRP HB2  H N N 413 
TRP HB3  H N N 414 
TRP HD1  H N N 415 
TRP HE1  H N N 416 
TRP HE3  H N N 417 
TRP HZ2  H N N 418 
TRP HZ3  H N N 419 
TRP HH2  H N N 420 
TRP HXT  H N N 421 
TYR N    N N N 422 
TYR CA   C N S 423 
TYR C    C N N 424 
TYR O    O N N 425 
TYR CB   C N N 426 
TYR CG   C Y N 427 
TYR CD1  C Y N 428 
TYR CD2  C Y N 429 
TYR CE1  C Y N 430 
TYR CE2  C Y N 431 
TYR CZ   C Y N 432 
TYR OH   O N N 433 
TYR OXT  O N N 434 
TYR H    H N N 435 
TYR H2   H N N 436 
TYR HA   H N N 437 
TYR HB2  H N N 438 
TYR HB3  H N N 439 
TYR HD1  H N N 440 
TYR HD2  H N N 441 
TYR HE1  H N N 442 
TYR HE2  H N N 443 
TYR HH   H N N 444 
TYR HXT  H N N 445 
VAL N    N N N 446 
VAL CA   C N S 447 
VAL C    C N N 448 
VAL O    O N N 449 
VAL CB   C N N 450 
VAL CG1  C N N 451 
VAL CG2  C N N 452 
VAL OXT  O N N 453 
VAL H    H N N 454 
VAL H2   H N N 455 
VAL HA   H N N 456 
VAL HB   H N N 457 
VAL HG11 H N N 458 
VAL HG12 H N N 459 
VAL HG13 H N N 460 
VAL HG21 H N N 461 
VAL HG22 H N N 462 
VAL HG23 H N N 463 
VAL HXT  H N N 464 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BMA C1  C2   sing N N 70  
BMA C1  O1   sing N N 71  
BMA C1  O5   sing N N 72  
BMA C1  H1   sing N N 73  
BMA C2  C3   sing N N 74  
BMA C2  O2   sing N N 75  
BMA C2  H2   sing N N 76  
BMA C3  C4   sing N N 77  
BMA C3  O3   sing N N 78  
BMA C3  H3   sing N N 79  
BMA C4  C5   sing N N 80  
BMA C4  O4   sing N N 81  
BMA C4  H4   sing N N 82  
BMA C5  C6   sing N N 83  
BMA C5  O5   sing N N 84  
BMA C5  H5   sing N N 85  
BMA C6  O6   sing N N 86  
BMA C6  H61  sing N N 87  
BMA C6  H62  sing N N 88  
BMA O1  HO1  sing N N 89  
BMA O2  HO2  sing N N 90  
BMA O3  HO3  sing N N 91  
BMA O4  HO4  sing N N 92  
BMA O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
FUC C1  C2   sing N N 107 
FUC C1  O1   sing N N 108 
FUC C1  O5   sing N N 109 
FUC C1  H1   sing N N 110 
FUC C2  C3   sing N N 111 
FUC C2  O2   sing N N 112 
FUC C2  H2   sing N N 113 
FUC C3  C4   sing N N 114 
FUC C3  O3   sing N N 115 
FUC C3  H3   sing N N 116 
FUC C4  C5   sing N N 117 
FUC C4  O4   sing N N 118 
FUC C4  H4   sing N N 119 
FUC C5  C6   sing N N 120 
FUC C5  O5   sing N N 121 
FUC C5  H5   sing N N 122 
FUC C6  H61  sing N N 123 
FUC C6  H62  sing N N 124 
FUC C6  H63  sing N N 125 
FUC O1  HO1  sing N N 126 
FUC O2  HO2  sing N N 127 
FUC O3  HO3  sing N N 128 
FUC O4  HO4  sing N N 129 
GLN N   CA   sing N N 130 
GLN N   H    sing N N 131 
GLN N   H2   sing N N 132 
GLN CA  C    sing N N 133 
GLN CA  CB   sing N N 134 
GLN CA  HA   sing N N 135 
GLN C   O    doub N N 136 
GLN C   OXT  sing N N 137 
GLN CB  CG   sing N N 138 
GLN CB  HB2  sing N N 139 
GLN CB  HB3  sing N N 140 
GLN CG  CD   sing N N 141 
GLN CG  HG2  sing N N 142 
GLN CG  HG3  sing N N 143 
GLN CD  OE1  doub N N 144 
GLN CD  NE2  sing N N 145 
GLN NE2 HE21 sing N N 146 
GLN NE2 HE22 sing N N 147 
GLN OXT HXT  sing N N 148 
GLU N   CA   sing N N 149 
GLU N   H    sing N N 150 
GLU N   H2   sing N N 151 
GLU CA  C    sing N N 152 
GLU CA  CB   sing N N 153 
GLU CA  HA   sing N N 154 
GLU C   O    doub N N 155 
GLU C   OXT  sing N N 156 
GLU CB  CG   sing N N 157 
GLU CB  HB2  sing N N 158 
GLU CB  HB3  sing N N 159 
GLU CG  CD   sing N N 160 
GLU CG  HG2  sing N N 161 
GLU CG  HG3  sing N N 162 
GLU CD  OE1  doub N N 163 
GLU CD  OE2  sing N N 164 
GLU OE2 HE2  sing N N 165 
GLU OXT HXT  sing N N 166 
GLY N   CA   sing N N 167 
GLY N   H    sing N N 168 
GLY N   H2   sing N N 169 
GLY CA  C    sing N N 170 
GLY CA  HA2  sing N N 171 
GLY CA  HA3  sing N N 172 
GLY C   O    doub N N 173 
GLY C   OXT  sing N N 174 
GLY OXT HXT  sing N N 175 
HIS N   CA   sing N N 176 
HIS N   H    sing N N 177 
HIS N   H2   sing N N 178 
HIS CA  C    sing N N 179 
HIS CA  CB   sing N N 180 
HIS CA  HA   sing N N 181 
HIS C   O    doub N N 182 
HIS C   OXT  sing N N 183 
HIS CB  CG   sing N N 184 
HIS CB  HB2  sing N N 185 
HIS CB  HB3  sing N N 186 
HIS CG  ND1  sing Y N 187 
HIS CG  CD2  doub Y N 188 
HIS ND1 CE1  doub Y N 189 
HIS ND1 HD1  sing N N 190 
HIS CD2 NE2  sing Y N 191 
HIS CD2 HD2  sing N N 192 
HIS CE1 NE2  sing Y N 193 
HIS CE1 HE1  sing N N 194 
HIS NE2 HE2  sing N N 195 
HIS OXT HXT  sing N N 196 
ILE N   CA   sing N N 197 
ILE N   H    sing N N 198 
ILE N   H2   sing N N 199 
ILE CA  C    sing N N 200 
ILE CA  CB   sing N N 201 
ILE CA  HA   sing N N 202 
ILE C   O    doub N N 203 
ILE C   OXT  sing N N 204 
ILE CB  CG1  sing N N 205 
ILE CB  CG2  sing N N 206 
ILE CB  HB   sing N N 207 
ILE CG1 CD1  sing N N 208 
ILE CG1 HG12 sing N N 209 
ILE CG1 HG13 sing N N 210 
ILE CG2 HG21 sing N N 211 
ILE CG2 HG22 sing N N 212 
ILE CG2 HG23 sing N N 213 
ILE CD1 HD11 sing N N 214 
ILE CD1 HD12 sing N N 215 
ILE CD1 HD13 sing N N 216 
ILE OXT HXT  sing N N 217 
LEU N   CA   sing N N 218 
LEU N   H    sing N N 219 
LEU N   H2   sing N N 220 
LEU CA  C    sing N N 221 
LEU CA  CB   sing N N 222 
LEU CA  HA   sing N N 223 
LEU C   O    doub N N 224 
LEU C   OXT  sing N N 225 
LEU CB  CG   sing N N 226 
LEU CB  HB2  sing N N 227 
LEU CB  HB3  sing N N 228 
LEU CG  CD1  sing N N 229 
LEU CG  CD2  sing N N 230 
LEU CG  HG   sing N N 231 
LEU CD1 HD11 sing N N 232 
LEU CD1 HD12 sing N N 233 
LEU CD1 HD13 sing N N 234 
LEU CD2 HD21 sing N N 235 
LEU CD2 HD22 sing N N 236 
LEU CD2 HD23 sing N N 237 
LEU OXT HXT  sing N N 238 
LYS N   CA   sing N N 239 
LYS N   H    sing N N 240 
LYS N   H2   sing N N 241 
LYS CA  C    sing N N 242 
LYS CA  CB   sing N N 243 
LYS CA  HA   sing N N 244 
LYS C   O    doub N N 245 
LYS C   OXT  sing N N 246 
LYS CB  CG   sing N N 247 
LYS CB  HB2  sing N N 248 
LYS CB  HB3  sing N N 249 
LYS CG  CD   sing N N 250 
LYS CG  HG2  sing N N 251 
LYS CG  HG3  sing N N 252 
LYS CD  CE   sing N N 253 
LYS CD  HD2  sing N N 254 
LYS CD  HD3  sing N N 255 
LYS CE  NZ   sing N N 256 
LYS CE  HE2  sing N N 257 
LYS CE  HE3  sing N N 258 
LYS NZ  HZ1  sing N N 259 
LYS NZ  HZ2  sing N N 260 
LYS NZ  HZ3  sing N N 261 
LYS OXT HXT  sing N N 262 
MET N   CA   sing N N 263 
MET N   H    sing N N 264 
MET N   H2   sing N N 265 
MET CA  C    sing N N 266 
MET CA  CB   sing N N 267 
MET CA  HA   sing N N 268 
MET C   O    doub N N 269 
MET C   OXT  sing N N 270 
MET CB  CG   sing N N 271 
MET CB  HB2  sing N N 272 
MET CB  HB3  sing N N 273 
MET CG  SD   sing N N 274 
MET CG  HG2  sing N N 275 
MET CG  HG3  sing N N 276 
MET SD  CE   sing N N 277 
MET CE  HE1  sing N N 278 
MET CE  HE2  sing N N 279 
MET CE  HE3  sing N N 280 
MET OXT HXT  sing N N 281 
NAG C1  C2   sing N N 282 
NAG C1  O1   sing N N 283 
NAG C1  O5   sing N N 284 
NAG C1  H1   sing N N 285 
NAG C2  C3   sing N N 286 
NAG C2  N2   sing N N 287 
NAG C2  H2   sing N N 288 
NAG C3  C4   sing N N 289 
NAG C3  O3   sing N N 290 
NAG C3  H3   sing N N 291 
NAG C4  C5   sing N N 292 
NAG C4  O4   sing N N 293 
NAG C4  H4   sing N N 294 
NAG C5  C6   sing N N 295 
NAG C5  O5   sing N N 296 
NAG C5  H5   sing N N 297 
NAG C6  O6   sing N N 298 
NAG C6  H61  sing N N 299 
NAG C6  H62  sing N N 300 
NAG C7  C8   sing N N 301 
NAG C7  N2   sing N N 302 
NAG C7  O7   doub N N 303 
NAG C8  H81  sing N N 304 
NAG C8  H82  sing N N 305 
NAG C8  H83  sing N N 306 
NAG N2  HN2  sing N N 307 
NAG O1  HO1  sing N N 308 
NAG O3  HO3  sing N N 309 
NAG O4  HO4  sing N N 310 
NAG O6  HO6  sing N N 311 
PHE N   CA   sing N N 312 
PHE N   H    sing N N 313 
PHE N   H2   sing N N 314 
PHE CA  C    sing N N 315 
PHE CA  CB   sing N N 316 
PHE CA  HA   sing N N 317 
PHE C   O    doub N N 318 
PHE C   OXT  sing N N 319 
PHE CB  CG   sing N N 320 
PHE CB  HB2  sing N N 321 
PHE CB  HB3  sing N N 322 
PHE CG  CD1  doub Y N 323 
PHE CG  CD2  sing Y N 324 
PHE CD1 CE1  sing Y N 325 
PHE CD1 HD1  sing N N 326 
PHE CD2 CE2  doub Y N 327 
PHE CD2 HD2  sing N N 328 
PHE CE1 CZ   doub Y N 329 
PHE CE1 HE1  sing N N 330 
PHE CE2 CZ   sing Y N 331 
PHE CE2 HE2  sing N N 332 
PHE CZ  HZ   sing N N 333 
PHE OXT HXT  sing N N 334 
PRO N   CA   sing N N 335 
PRO N   CD   sing N N 336 
PRO N   H    sing N N 337 
PRO CA  C    sing N N 338 
PRO CA  CB   sing N N 339 
PRO CA  HA   sing N N 340 
PRO C   O    doub N N 341 
PRO C   OXT  sing N N 342 
PRO CB  CG   sing N N 343 
PRO CB  HB2  sing N N 344 
PRO CB  HB3  sing N N 345 
PRO CG  CD   sing N N 346 
PRO CG  HG2  sing N N 347 
PRO CG  HG3  sing N N 348 
PRO CD  HD2  sing N N 349 
PRO CD  HD3  sing N N 350 
PRO OXT HXT  sing N N 351 
SER N   CA   sing N N 352 
SER N   H    sing N N 353 
SER N   H2   sing N N 354 
SER CA  C    sing N N 355 
SER CA  CB   sing N N 356 
SER CA  HA   sing N N 357 
SER C   O    doub N N 358 
SER C   OXT  sing N N 359 
SER CB  OG   sing N N 360 
SER CB  HB2  sing N N 361 
SER CB  HB3  sing N N 362 
SER OG  HG   sing N N 363 
SER OXT HXT  sing N N 364 
THR N   CA   sing N N 365 
THR N   H    sing N N 366 
THR N   H2   sing N N 367 
THR CA  C    sing N N 368 
THR CA  CB   sing N N 369 
THR CA  HA   sing N N 370 
THR C   O    doub N N 371 
THR C   OXT  sing N N 372 
THR CB  OG1  sing N N 373 
THR CB  CG2  sing N N 374 
THR CB  HB   sing N N 375 
THR OG1 HG1  sing N N 376 
THR CG2 HG21 sing N N 377 
THR CG2 HG22 sing N N 378 
THR CG2 HG23 sing N N 379 
THR OXT HXT  sing N N 380 
TRP N   CA   sing N N 381 
TRP N   H    sing N N 382 
TRP N   H2   sing N N 383 
TRP CA  C    sing N N 384 
TRP CA  CB   sing N N 385 
TRP CA  HA   sing N N 386 
TRP C   O    doub N N 387 
TRP C   OXT  sing N N 388 
TRP CB  CG   sing N N 389 
TRP CB  HB2  sing N N 390 
TRP CB  HB3  sing N N 391 
TRP CG  CD1  doub Y N 392 
TRP CG  CD2  sing Y N 393 
TRP CD1 NE1  sing Y N 394 
TRP CD1 HD1  sing N N 395 
TRP CD2 CE2  doub Y N 396 
TRP CD2 CE3  sing Y N 397 
TRP NE1 CE2  sing Y N 398 
TRP NE1 HE1  sing N N 399 
TRP CE2 CZ2  sing Y N 400 
TRP CE3 CZ3  doub Y N 401 
TRP CE3 HE3  sing N N 402 
TRP CZ2 CH2  doub Y N 403 
TRP CZ2 HZ2  sing N N 404 
TRP CZ3 CH2  sing Y N 405 
TRP CZ3 HZ3  sing N N 406 
TRP CH2 HH2  sing N N 407 
TRP OXT HXT  sing N N 408 
TYR N   CA   sing N N 409 
TYR N   H    sing N N 410 
TYR N   H2   sing N N 411 
TYR CA  C    sing N N 412 
TYR CA  CB   sing N N 413 
TYR CA  HA   sing N N 414 
TYR C   O    doub N N 415 
TYR C   OXT  sing N N 416 
TYR CB  CG   sing N N 417 
TYR CB  HB2  sing N N 418 
TYR CB  HB3  sing N N 419 
TYR CG  CD1  doub Y N 420 
TYR CG  CD2  sing Y N 421 
TYR CD1 CE1  sing Y N 422 
TYR CD1 HD1  sing N N 423 
TYR CD2 CE2  doub Y N 424 
TYR CD2 HD2  sing N N 425 
TYR CE1 CZ   doub Y N 426 
TYR CE1 HE1  sing N N 427 
TYR CE2 CZ   sing Y N 428 
TYR CE2 HE2  sing N N 429 
TYR CZ  OH   sing N N 430 
TYR OH  HH   sing N N 431 
TYR OXT HXT  sing N N 432 
VAL N   CA   sing N N 433 
VAL N   H    sing N N 434 
VAL N   H2   sing N N 435 
VAL CA  C    sing N N 436 
VAL CA  CB   sing N N 437 
VAL CA  HA   sing N N 438 
VAL C   O    doub N N 439 
VAL C   OXT  sing N N 440 
VAL CB  CG1  sing N N 441 
VAL CB  CG2  sing N N 442 
VAL CB  HB   sing N N 443 
VAL CG1 HG11 sing N N 444 
VAL CG1 HG12 sing N N 445 
VAL CG1 HG13 sing N N 446 
VAL CG2 HG21 sing N N 447 
VAL CG2 HG22 sing N N 448 
VAL CG2 HG23 sing N N 449 
VAL OXT HXT  sing N N 450 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-12-21 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9MNH 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Angavokely virus (AngV) fusion (F) protein ectodomain in pre-fusion conformation' 
# 
_em_buffer_component.buffer_id             1 
_em_buffer_component.concentration         1 
_em_buffer_component.concentration_units   1 
_em_buffer_component.formula               Na2HPO4/NaH2PO4 
_em_buffer_component.id                    1 
_em_buffer_component.name                  'Phosphate Buffer' 
# 
_em_ctf_correction.details                  
'Micrographs were curated through contrast transfer function (CTF) where greater than 30 angstrom were discarded' 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    YES 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.06 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    'Outer Membrane' 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2974046 
_em_entity_assembly_naturalsource.organism             'Angavokely henipavirus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              palphaH 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              'Micrographs were motion-corrected and aligned micrographs were used for the processing' 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               2.8 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         28 
_em_image_recording.details                             'Images were collected in a movie -mode at 22 frames per second' 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    3 
_em_image_recording.num_real_images                     24000 
# 
_em_particle_selection.details                  'Particles were picked using automated blob picker and extracted' 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   13247526 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? cryoSPARC       v4.5.3      
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?               ?           
MASKING                         ? 3  ? ? ? ?               ?           
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC       v4.5.3      
'LAYERLINE INDEXING'            ? 5  ? ? ? ?               ?           
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?               ?           
'MODEL FITTING'                 ? 7  ? 1 ? 'UCSF ChimeraX' 1.6.1       
OTHER                           ? 8  ? ? ? ?               ?           
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? ?               ?           
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? ?               ?           
CLASSIFICATION                  ? 11 1 ? ? cryoSPARC       v4.5.3      
RECONSTRUCTION                  ? 12 1 ? ? cryoSPARC       v4.5.3      
'VOLUME SELECTION'              ? 13 1 1 1 ?               ?           
'SERIES ALIGNMENT'              ? 14 1 1 1 ?               ?           
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?               ?           
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?               ?           
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?               ?           
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?               ?           
'MODEL REFINEMENT'              ? 19 ? 1 ? PHENIX          1.21.1_5286 
# 
_em_specimen.concentration           1.5 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
2 BMA 3 n 
3 NAG 1 n 
3 NAG 2 n 
3 BMA 3 n 
3 FUC 4 n 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      SwissModel 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9MNH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . VAL A 1 1   ? 147.242 182.898 161.086 1.00 89.66  ? 22  VAL A N   1 
ATOM   2     C CA  . VAL A 1 1   ? 147.677 181.517 161.238 1.00 89.66  ? 22  VAL A CA  1 
ATOM   3     C C   . VAL A 1 1   ? 146.466 180.572 161.156 1.00 89.66  ? 22  VAL A C   1 
ATOM   4     O O   . VAL A 1 1   ? 145.378 180.880 161.648 1.00 89.66  ? 22  VAL A O   1 
ATOM   5     C CB  . VAL A 1 1   ? 148.506 181.345 162.558 1.00 89.66  ? 22  VAL A CB  1 
ATOM   6     C CG1 . VAL A 1 1   ? 147.669 181.616 163.811 1.00 89.66  ? 22  VAL A CG1 1 
ATOM   7     C CG2 . VAL A 1 1   ? 149.172 179.974 162.626 1.00 89.66  ? 22  VAL A CG2 1 
ATOM   8     N N   . ASP A 1 2   ? 146.646 179.448 160.465 1.00 87.17  ? 23  ASP A N   1 
ATOM   9     C CA  . ASP A 1 2   ? 145.608 178.435 160.320 1.00 87.17  ? 23  ASP A CA  1 
ATOM   10    C C   . ASP A 1 2   ? 146.014 177.200 161.115 1.00 87.17  ? 23  ASP A C   1 
ATOM   11    O O   . ASP A 1 2   ? 147.009 176.545 160.786 1.00 87.17  ? 23  ASP A O   1 
ATOM   12    C CB  . ASP A 1 2   ? 145.389 178.087 158.847 1.00 87.17  ? 23  ASP A CB  1 
ATOM   13    C CG  . ASP A 1 2   ? 144.068 177.380 158.602 1.00 87.17  ? 23  ASP A CG  1 
ATOM   14    O OD1 . ASP A 1 2   ? 143.952 176.188 158.955 1.00 87.17  ? 23  ASP A OD1 1 
ATOM   15    O OD2 . ASP A 1 2   ? 143.144 178.018 158.054 1.00 87.17  ? 23  ASP A OD2 1 
ATOM   16    N N   . PHE A 1 3   ? 145.245 176.883 162.157 1.00 72.62  ? 24  PHE A N   1 
ATOM   17    C CA  . PHE A 1 3   ? 145.586 175.768 163.030 1.00 72.62  ? 24  PHE A CA  1 
ATOM   18    C C   . PHE A 1 3   ? 145.111 174.419 162.507 1.00 72.62  ? 24  PHE A C   1 
ATOM   19    O O   . PHE A 1 3   ? 145.548 173.392 163.032 1.00 72.62  ? 24  PHE A O   1 
ATOM   20    C CB  . PHE A 1 3   ? 145.020 176.005 164.431 1.00 72.62  ? 24  PHE A CB  1 
ATOM   21    C CG  . PHE A 1 3   ? 145.671 177.146 165.159 1.00 72.62  ? 24  PHE A CG  1 
ATOM   22    C CD1 . PHE A 1 3   ? 146.981 177.041 165.601 1.00 72.62  ? 24  PHE A CD1 1 
ATOM   23    C CD2 . PHE A 1 3   ? 144.977 178.323 165.397 1.00 72.62  ? 24  PHE A CD2 1 
ATOM   24    C CE1 . PHE A 1 3   ? 147.589 178.090 166.271 1.00 72.62  ? 24  PHE A CE1 1 
ATOM   25    C CE2 . PHE A 1 3   ? 145.578 179.376 166.066 1.00 72.62  ? 24  PHE A CE2 1 
ATOM   26    C CZ  . PHE A 1 3   ? 146.886 179.257 166.504 1.00 72.62  ? 24  PHE A CZ  1 
ATOM   27    N N   . GLU A 1 4   ? 144.244 174.390 161.492 1.00 75.95  ? 25  GLU A N   1 
ATOM   28    C CA  . GLU A 1 4   ? 143.796 173.113 160.941 1.00 75.95  ? 25  GLU A CA  1 
ATOM   29    C C   . GLU A 1 4   ? 144.904 172.442 160.136 1.00 75.95  ? 25  GLU A C   1 
ATOM   30    O O   . GLU A 1 4   ? 145.170 171.245 160.302 1.00 75.95  ? 25  GLU A O   1 
ATOM   31    C CB  . GLU A 1 4   ? 142.553 173.320 160.076 1.00 75.95  ? 25  GLU A CB  1 
ATOM   32    C CG  . GLU A 1 4   ? 141.255 173.408 160.860 1.00 75.95  ? 25  GLU A CG  1 
ATOM   33    C CD  . GLU A 1 4   ? 141.032 174.775 161.472 1.00 75.95  ? 25  GLU A CD  1 
ATOM   34    O OE1 . GLU A 1 4   ? 141.659 175.747 161.001 1.00 75.95  ? 25  GLU A OE1 1 
ATOM   35    O OE2 . GLU A 1 4   ? 140.228 174.879 162.422 1.00 75.95  ? 25  GLU A OE2 1 
ATOM   36    N N   . ARG A 1 5   ? 145.571 173.208 159.268 1.00 77.54  ? 26  ARG A N   1 
ATOM   37    C CA  . ARG A 1 5   ? 146.684 172.671 158.490 1.00 77.54  ? 26  ARG A CA  1 
ATOM   38    C C   . ARG A 1 5   ? 147.875 172.342 159.384 1.00 77.54  ? 26  ARG A C   1 
ATOM   39    O O   . ARG A 1 5   ? 148.555 171.327 159.180 1.00 77.54  ? 26  ARG A O   1 
ATOM   40    C CB  . ARG A 1 5   ? 147.085 173.668 157.404 1.00 77.54  ? 26  ARG A CB  1 
ATOM   41    C CG  . ARG A 1 5   ? 145.911 174.240 156.623 1.00 77.54  ? 26  ARG A CG  1 
ATOM   42    C CD  . ARG A 1 5   ? 146.380 175.024 155.407 1.00 77.54  ? 26  ARG A CD  1 
ATOM   43    N NE  . ARG A 1 5   ? 147.099 174.190 154.451 1.00 77.54  ? 26  ARG A NE  1 
ATOM   44    C CZ  . ARG A 1 5   ? 146.518 173.476 153.496 1.00 77.54  ? 26  ARG A CZ  1 
ATOM   45    N NH1 . ARG A 1 5   ? 145.205 173.475 153.335 1.00 77.54  ? 26  ARG A NH1 1 
ATOM   46    N NH2 . ARG A 1 5   ? 147.275 172.749 152.679 1.00 77.54  ? 26  ARG A NH2 1 
ATOM   47    N N   . LEU A 1 6   ? 148.128 173.179 160.392 1.00 62.76  ? 27  LEU A N   1 
ATOM   48    C CA  . LEU A 1 6   ? 149.218 172.922 161.323 1.00 62.76  ? 27  LEU A CA  1 
ATOM   49    C C   . LEU A 1 6   ? 148.893 171.769 162.267 1.00 62.76  ? 27  LEU A C   1 
ATOM   50    O O   . LEU A 1 6   ? 149.813 171.140 162.797 1.00 62.76  ? 27  LEU A O   1 
ATOM   51    C CB  . LEU A 1 6   ? 149.544 174.211 162.087 1.00 62.76  ? 27  LEU A CB  1 
ATOM   52    C CG  . LEU A 1 6   ? 150.840 174.374 162.888 1.00 62.76  ? 27  LEU A CG  1 
ATOM   53    C CD1 . LEU A 1 6   ? 151.289 175.818 162.804 1.00 62.76  ? 27  LEU A CD1 1 
ATOM   54    C CD2 . LEU A 1 6   ? 150.664 174.000 164.345 1.00 62.76  ? 27  LEU A CD2 1 
ATOM   55    N N   . ALA A 1 7   ? 147.608 171.473 162.481 1.00 58.68  ? 28  ALA A N   1 
ATOM   56    C CA  . ALA A 1 7   ? 147.226 170.253 163.181 1.00 58.68  ? 28  ALA A CA  1 
ATOM   57    C C   . ALA A 1 7   ? 147.354 169.032 162.287 1.00 58.68  ? 28  ALA A C   1 
ATOM   58    O O   . ALA A 1 7   ? 147.626 167.932 162.780 1.00 58.68  ? 28  ALA A O   1 
ATOM   59    C CB  . ALA A 1 7   ? 145.796 170.371 163.710 1.00 58.68  ? 28  ALA A CB  1 
ATOM   60    N N   . SER A 1 8   ? 147.144 169.208 160.982 1.00 68.17  ? 29  SER A N   1 
ATOM   61    C CA  . SER A 1 8   ? 147.351 168.112 160.042 1.00 68.17  ? 29  SER A CA  1 
ATOM   62    C C   . SER A 1 8   ? 148.828 167.759 159.916 1.00 68.17  ? 29  SER A C   1 
ATOM   63    O O   . SER A 1 8   ? 149.176 166.585 159.743 1.00 68.17  ? 29  SER A O   1 
ATOM   64    C CB  . SER A 1 8   ? 146.768 168.474 158.676 1.00 68.17  ? 29  SER A CB  1 
ATOM   65    O OG  . SER A 1 8   ? 145.376 168.216 158.632 1.00 68.17  ? 29  SER A OG  1 
ATOM   66    N N   . ILE A 1 9   ? 149.714 168.755 159.998 1.00 64.01  ? 30  ILE A N   1 
ATOM   67    C CA  . ILE A 1 9   ? 151.139 168.465 159.851 1.00 64.01  ? 30  ILE A CA  1 
ATOM   68    C C   . ILE A 1 9   ? 151.732 167.900 161.145 1.00 64.01  ? 30  ILE A C   1 
ATOM   69    O O   . ILE A 1 9   ? 152.779 167.241 161.104 1.00 64.01  ? 30  ILE A O   1 
ATOM   70    C CB  . ILE A 1 9   ? 151.887 169.721 159.356 1.00 64.01  ? 30  ILE A CB  1 
ATOM   71    C CG1 . ILE A 1 9   ? 153.230 169.358 158.713 1.00 64.01  ? 30  ILE A CG1 1 
ATOM   72    C CG2 . ILE A 1 9   ? 152.140 170.707 160.482 1.00 64.01  ? 30  ILE A CG2 1 
ATOM   73    C CD1 . ILE A 1 9   ? 153.100 168.563 157.434 1.00 64.01  ? 30  ILE A CD1 1 
ATOM   74    N N   . GLY A 1 10  ? 151.074 168.092 162.288 1.00 49.08  ? 31  GLY A N   1 
ATOM   75    C CA  . GLY A 1 10  ? 151.548 167.489 163.520 1.00 49.08  ? 31  GLY A CA  1 
ATOM   76    C C   . GLY A 1 10  ? 151.840 168.451 164.655 1.00 49.08  ? 31  GLY A C   1 
ATOM   77    O O   . GLY A 1 10  ? 152.648 168.145 165.536 1.00 49.08  ? 31  GLY A O   1 
ATOM   78    N N   . GLY A 1 11  ? 151.195 169.614 164.651 1.00 43.34  ? 32  GLY A N   1 
ATOM   79    C CA  . GLY A 1 11  ? 151.357 170.568 165.732 1.00 43.34  ? 32  GLY A CA  1 
ATOM   80    C C   . GLY A 1 11  ? 150.032 170.981 166.336 1.00 43.34  ? 32  GLY A C   1 
ATOM   81    O O   . GLY A 1 11  ? 149.114 171.377 165.616 1.00 43.34  ? 32  GLY A O   1 
ATOM   82    N N   . ILE A 1 12  ? 149.911 170.907 167.657 1.00 42.83  ? 33  ILE A N   1 
ATOM   83    C CA  . ILE A 1 12  ? 148.644 171.121 168.344 1.00 42.83  ? 33  ILE A CA  1 
ATOM   84    C C   . ILE A 1 12  ? 148.736 172.422 169.130 1.00 42.83  ? 33  ILE A C   1 
ATOM   85    O O   . ILE A 1 12  ? 149.745 172.679 169.797 1.00 42.83  ? 33  ILE A O   1 
ATOM   86    C CB  . ILE A 1 12  ? 148.309 169.922 169.247 1.00 42.83  ? 33  ILE A CB  1 
ATOM   87    C CG1 . ILE A 1 12  ? 148.302 168.650 168.398 1.00 42.83  ? 33  ILE A CG1 1 
ATOM   88    C CG2 . ILE A 1 12  ? 146.970 170.109 169.946 1.00 42.83  ? 33  ILE A CG2 1 
ATOM   89    C CD1 . ILE A 1 12  ? 148.382 167.379 169.181 1.00 42.83  ? 33  ILE A CD1 1 
ATOM   90    N N   . LYS A 1 13  ? 147.698 173.253 169.023 1.00 40.64  ? 34  LYS A N   1 
ATOM   91    C CA  . LYS A 1 13  ? 147.691 174.564 169.663 1.00 40.64  ? 34  LYS A CA  1 
ATOM   92    C C   . LYS A 1 13  ? 147.605 174.419 171.177 1.00 40.64  ? 34  LYS A C   1 
ATOM   93    O O   . LYS A 1 13  ? 146.649 173.839 171.702 1.00 40.64  ? 34  LYS A O   1 
ATOM   94    C CB  . LYS A 1 13  ? 146.525 175.398 169.141 1.00 40.64  ? 34  LYS A CB  1 
ATOM   95    C CG  . LYS A 1 13  ? 146.341 176.724 169.864 1.00 40.64  ? 34  LYS A CG  1 
ATOM   96    C CD  . LYS A 1 13  ? 145.039 177.400 169.466 1.00 40.64  ? 34  LYS A CD  1 
ATOM   97    C CE  . LYS A 1 13  ? 143.908 177.001 170.398 1.00 40.64  ? 34  LYS A CE  1 
ATOM   98    N NZ  . LYS A 1 13  ? 144.264 177.225 171.825 1.00 40.64  ? 34  LYS A NZ  1 
ATOM   99    N N   . GLY A 1 14  ? 148.602 174.947 171.873 1.00 37.61  ? 35  GLY A N   1 
ATOM   100   C CA  . GLY A 1 14  ? 148.662 174.907 173.319 1.00 37.61  ? 35  GLY A CA  1 
ATOM   101   C C   . GLY A 1 14  ? 148.004 176.110 173.956 1.00 37.61  ? 35  GLY A C   1 
ATOM   102   O O   . GLY A 1 14  ? 147.094 176.725 173.391 1.00 37.61  ? 35  GLY A O   1 
ATOM   103   N N   . HIS A 1 15  ? 148.474 176.453 175.152 1.00 36.00  ? 36  HIS A N   1 
ATOM   104   C CA  . HIS A 1 15  ? 147.888 177.545 175.915 1.00 36.00  ? 36  HIS A CA  1 
ATOM   105   C C   . HIS A 1 15  ? 148.242 178.897 175.303 1.00 36.00  ? 36  HIS A C   1 
ATOM   106   O O   . HIS A 1 15  ? 149.215 179.043 174.560 1.00 36.00  ? 36  HIS A O   1 
ATOM   107   C CB  . HIS A 1 15  ? 148.366 177.515 177.366 1.00 36.00  ? 36  HIS A CB  1 
ATOM   108   C CG  . HIS A 1 15  ? 148.515 176.138 177.930 1.00 36.00  ? 36  HIS A CG  1 
ATOM   109   N ND1 . HIS A 1 15  ? 149.671 175.400 177.796 1.00 36.00  ? 36  HIS A ND1 1 
ATOM   110   C CD2 . HIS A 1 15  ? 147.654 175.364 178.631 1.00 36.00  ? 36  HIS A CD2 1 
ATOM   111   C CE1 . HIS A 1 15  ? 149.517 174.232 178.393 1.00 36.00  ? 36  HIS A CE1 1 
ATOM   112   N NE2 . HIS A 1 15  ? 148.301 174.184 178.908 1.00 36.00  ? 36  HIS A NE2 1 
ATOM   113   N N   . SER A 1 16  ? 147.417 179.892 175.618 1.00 37.60  ? 37  SER A N   1 
ATOM   114   C CA  . SER A 1 16  ? 147.653 181.275 175.226 1.00 37.60  ? 37  SER A CA  1 
ATOM   115   C C   . SER A 1 16  ? 148.057 182.067 176.462 1.00 37.60  ? 37  SER A C   1 
ATOM   116   O O   . SER A 1 16  ? 147.317 182.098 177.452 1.00 37.60  ? 37  SER A O   1 
ATOM   117   C CB  . SER A 1 16  ? 146.411 181.883 174.575 1.00 37.60  ? 37  SER A CB  1 
ATOM   118   O OG  . SER A 1 16  ? 146.109 181.238 173.349 1.00 37.60  ? 37  SER A OG  1 
ATOM   119   N N   . LYS A 1 17  ? 149.226 182.701 176.401 1.00 34.14  ? 38  LYS A N   1 
ATOM   120   C CA  . LYS A 1 17  ? 149.774 183.458 177.517 1.00 34.14  ? 38  LYS A CA  1 
ATOM   121   C C   . LYS A 1 17  ? 150.150 184.860 177.059 1.00 34.14  ? 38  LYS A C   1 
ATOM   122   O O   . LYS A 1 17  ? 150.392 185.109 175.875 1.00 34.14  ? 38  LYS A O   1 
ATOM   123   C CB  . LYS A 1 17  ? 150.999 182.763 178.129 1.00 34.14  ? 38  LYS A CB  1 
ATOM   124   C CG  . LYS A 1 17  ? 150.703 181.407 178.750 1.00 34.14  ? 38  LYS A CG  1 
ATOM   125   C CD  . LYS A 1 17  ? 151.963 180.761 179.298 1.00 34.14  ? 38  LYS A CD  1 
ATOM   126   C CE  . LYS A 1 17  ? 151.690 179.345 179.778 1.00 34.14  ? 38  LYS A CE  1 
ATOM   127   N NZ  . LYS A 1 17  ? 150.801 179.320 180.973 1.00 34.14  ? 38  LYS A NZ  1 
ATOM   128   N N   . LEU A 1 18  ? 150.202 185.776 178.023 1.00 39.34  ? 39  LEU A N   1 
ATOM   129   C CA  . LEU A 1 18  ? 150.511 187.173 177.765 1.00 39.34  ? 39  LEU A CA  1 
ATOM   130   C C   . LEU A 1 18  ? 152.022 187.403 177.797 1.00 39.34  ? 39  LEU A C   1 
ATOM   131   O O   . LEU A 1 18  ? 152.817 186.478 177.976 1.00 39.34  ? 39  LEU A O   1 
ATOM   132   C CB  . LEU A 1 18  ? 149.804 188.073 178.779 1.00 39.34  ? 39  LEU A CB  1 
ATOM   133   C CG  . LEU A 1 18  ? 148.362 188.510 178.499 1.00 39.34  ? 39  LEU A CG  1 
ATOM   134   C CD1 . LEU A 1 18  ? 147.351 187.409 178.801 1.00 39.34  ? 39  LEU A CD1 1 
ATOM   135   C CD2 . LEU A 1 18  ? 148.039 189.766 179.288 1.00 39.34  ? 39  LEU A CD2 1 
ATOM   136   N N   . TYR A 1 19  ? 152.422 188.661 177.626 1.00 34.88  ? 40  TYR A N   1 
ATOM   137   C CA  . TYR A 1 19  ? 153.828 189.040 177.591 1.00 34.88  ? 40  TYR A CA  1 
ATOM   138   C C   . TYR A 1 19  ? 154.006 190.341 178.357 1.00 34.88  ? 40  TYR A C   1 
ATOM   139   O O   . TYR A 1 19  ? 153.355 191.340 178.041 1.00 34.88  ? 40  TYR A O   1 
ATOM   140   C CB  . TYR A 1 19  ? 154.312 189.196 176.144 1.00 34.88  ? 40  TYR A CB  1 
ATOM   141   C CG  . TYR A 1 19  ? 155.811 189.297 175.987 1.00 34.88  ? 40  TYR A CG  1 
ATOM   142   C CD1 . TYR A 1 19  ? 156.667 188.664 176.879 1.00 34.88  ? 40  TYR A CD1 1 
ATOM   143   C CD2 . TYR A 1 19  ? 156.370 190.010 174.932 1.00 34.88  ? 40  TYR A CD2 1 
ATOM   144   C CE1 . TYR A 1 19  ? 158.040 188.750 176.733 1.00 34.88  ? 40  TYR A CE1 1 
ATOM   145   C CE2 . TYR A 1 19  ? 157.740 190.101 174.778 1.00 34.88  ? 40  TYR A CE2 1 
ATOM   146   C CZ  . TYR A 1 19  ? 158.569 189.468 175.681 1.00 34.88  ? 40  TYR A CZ  1 
ATOM   147   O OH  . TYR A 1 19  ? 159.933 189.554 175.533 1.00 34.88  ? 40  TYR A OH  1 
ATOM   148   N N   . LYS A 1 20  ? 154.885 190.329 179.359 1.00 35.31  ? 41  LYS A N   1 
ATOM   149   C CA  . LYS A 1 20  ? 155.120 191.491 180.203 1.00 35.31  ? 41  LYS A CA  1 
ATOM   150   C C   . LYS A 1 20  ? 156.615 191.720 180.365 1.00 35.31  ? 41  LYS A C   1 
ATOM   151   O O   . LYS A 1 20  ? 157.395 190.766 180.436 1.00 35.31  ? 41  LYS A O   1 
ATOM   152   C CB  . LYS A 1 20  ? 154.460 191.324 181.575 1.00 35.31  ? 41  LYS A CB  1 
ATOM   153   C CG  . LYS A 1 20  ? 153.015 191.794 181.611 1.00 35.31  ? 41  LYS A CG  1 
ATOM   154   C CD  . LYS A 1 20  ? 152.333 191.469 182.932 1.00 35.31  ? 41  LYS A CD  1 
ATOM   155   C CE  . LYS A 1 20  ? 152.476 190.004 183.301 1.00 35.31  ? 41  LYS A CE  1 
ATOM   156   N NZ  . LYS A 1 20  ? 152.096 189.765 184.719 1.00 35.31  ? 41  LYS A NZ  1 
ATOM   157   N N   . ILE A 1 21  ? 157.007 192.993 180.423 1.00 40.61  ? 42  ILE A N   1 
ATOM   158   C CA  . ILE A 1 21  ? 158.406 193.402 180.465 1.00 40.61  ? 42  ILE A CA  1 
ATOM   159   C C   . ILE A 1 21  ? 158.636 194.222 181.728 1.00 40.61  ? 42  ILE A C   1 
ATOM   160   O O   . ILE A 1 21  ? 157.812 195.071 182.084 1.00 40.61  ? 42  ILE A O   1 
ATOM   161   C CB  . ILE A 1 21  ? 158.798 194.216 179.210 1.00 40.61  ? 42  ILE A CB  1 
ATOM   162   C CG1 . ILE A 1 21  ? 158.367 193.499 177.930 1.00 40.61  ? 42  ILE A CG1 1 
ATOM   163   C CG2 . ILE A 1 21  ? 160.298 194.463 179.154 1.00 40.61  ? 42  ILE A CG2 1 
ATOM   164   C CD1 . ILE A 1 21  ? 158.479 194.355 176.691 1.00 40.61  ? 42  ILE A CD1 1 
ATOM   165   N N   . LYS A 1 22  ? 159.743 193.954 182.416 1.00 44.57  ? 43  LYS A N   1 
ATOM   166   C CA  . LYS A 1 22  ? 160.160 194.812 183.517 1.00 44.57  ? 43  LYS A CA  1 
ATOM   167   C C   . LYS A 1 22  ? 160.652 196.147 182.968 1.00 44.57  ? 43  LYS A C   1 
ATOM   168   O O   . LYS A 1 22  ? 161.482 196.186 182.055 1.00 44.57  ? 43  LYS A O   1 
ATOM   169   C CB  . LYS A 1 22  ? 161.260 194.135 184.333 1.00 44.57  ? 43  LYS A CB  1 
ATOM   170   C CG  . LYS A 1 22  ? 161.613 194.854 185.625 1.00 44.57  ? 43  LYS A CG  1 
ATOM   171   C CD  . LYS A 1 22  ? 162.834 194.234 186.289 1.00 44.57  ? 43  LYS A CD  1 
ATOM   172   C CE  . LYS A 1 22  ? 164.124 194.866 185.790 1.00 44.57  ? 43  LYS A CE  1 
ATOM   173   N NZ  . LYS A 1 22  ? 164.301 196.255 186.297 1.00 44.57  ? 43  LYS A NZ  1 
ATOM   174   N N   . GLY A 1 23  ? 160.144 197.241 183.527 1.00 67.93  ? 44  GLY A N   1 
ATOM   175   C CA  . GLY A 1 23  ? 160.498 198.559 183.027 1.00 67.93  ? 44  GLY A CA  1 
ATOM   176   C C   . GLY A 1 23  ? 160.073 199.640 183.994 1.00 67.93  ? 44  GLY A C   1 
ATOM   177   O O   . GLY A 1 23  ? 159.393 199.379 184.991 1.00 67.93  ? 44  GLY A O   1 
ATOM   178   N N   . HIS A 1 24  ? 160.480 200.876 183.660 1.00 90.51  ? 45  HIS A N   1 
ATOM   179   C CA  . HIS A 1 24  ? 160.313 202.107 184.435 1.00 90.51  ? 45  HIS A CA  1 
ATOM   180   C C   . HIS A 1 24  ? 160.837 201.927 185.860 1.00 90.51  ? 45  HIS A C   1 
ATOM   181   O O   . HIS A 1 24  ? 160.048 201.733 186.794 1.00 90.51  ? 45  HIS A O   1 
ATOM   182   C CB  . HIS A 1 24  ? 158.843 202.552 184.429 1.00 90.51  ? 45  HIS A CB  1 
ATOM   183   C CG  . HIS A 1 24  ? 158.591 203.843 185.147 1.00 90.51  ? 45  HIS A CG  1 
ATOM   184   N ND1 . HIS A 1 24  ? 158.954 205.068 184.628 1.00 90.51  ? 45  HIS A ND1 1 
ATOM   185   C CD2 . HIS A 1 24  ? 158.009 204.099 186.342 1.00 90.51  ? 45  HIS A CD2 1 
ATOM   186   C CE1 . HIS A 1 24  ? 158.609 206.022 185.474 1.00 90.51  ? 45  HIS A CE1 1 
ATOM   187   N NE2 . HIS A 1 24  ? 158.034 205.461 186.523 1.00 90.51  ? 45  HIS A NE2 1 
ATOM   188   N N   . PRO A 1 25  ? 162.155 201.921 186.067 1.00 63.04  ? 46  PRO A N   1 
ATOM   189   C CA  . PRO A 1 25  ? 162.675 201.688 187.418 1.00 63.04  ? 46  PRO A CA  1 
ATOM   190   C C   . PRO A 1 25  ? 162.928 202.964 188.208 1.00 63.04  ? 46  PRO A C   1 
ATOM   191   O O   . PRO A 1 25  ? 163.427 203.969 187.697 1.00 63.04  ? 46  PRO A O   1 
ATOM   192   C CB  . PRO A 1 25  ? 163.991 200.946 187.146 1.00 63.04  ? 46  PRO A CB  1 
ATOM   193   C CG  . PRO A 1 25  ? 164.431 201.425 185.788 1.00 63.04  ? 46  PRO A CG  1 
ATOM   194   C CD  . PRO A 1 25  ? 163.242 202.029 185.076 1.00 63.04  ? 46  PRO A CD  1 
ATOM   195   N N   . THR A 1 26  ? 162.569 202.915 189.485 1.00 43.45  ? 47  THR A N   1 
ATOM   196   C CA  . THR A 1 26  ? 162.969 203.928 190.448 1.00 43.45  ? 47  THR A CA  1 
ATOM   197   C C   . THR A 1 26  ? 164.113 203.386 191.299 1.00 43.45  ? 47  THR A C   1 
ATOM   198   O O   . THR A 1 26  ? 164.367 202.180 191.342 1.00 43.45  ? 47  THR A O   1 
ATOM   199   C CB  . THR A 1 26  ? 161.791 204.356 191.329 1.00 43.45  ? 47  THR A CB  1 
ATOM   200   O OG1 . THR A 1 26  ? 162.206 205.406 192.212 1.00 43.45  ? 47  THR A OG1 1 
ATOM   201   C CG2 . THR A 1 26  ? 161.270 203.190 192.143 1.00 43.45  ? 47  THR A CG2 1 
ATOM   202   N N   . THR A 1 27  ? 164.815 204.292 191.968 1.00 38.77  ? 48  THR A N   1 
ATOM   203   C CA  . THR A 1 27  ? 166.072 203.963 192.624 1.00 38.77  ? 48  THR A CA  1 
ATOM   204   C C   . THR A 1 27  ? 165.927 204.001 194.139 1.00 38.77  ? 48  THR A C   1 
ATOM   205   O O   . THR A 1 27  ? 165.236 204.864 194.688 1.00 38.77  ? 48  THR A O   1 
ATOM   206   C CB  . THR A 1 27  ? 167.180 204.926 192.193 1.00 38.77  ? 48  THR A CB  1 
ATOM   207   O OG1 . THR A 1 27  ? 166.732 206.277 192.356 1.00 38.77  ? 48  THR A OG1 1 
ATOM   208   C CG2 . THR A 1 27  ? 167.546 204.693 190.737 1.00 38.77  ? 48  THR A CG2 1 
ATOM   209   N N   . LYS A 1 28  ? 166.585 203.055 194.805 1.00 27.02  ? 49  LYS A N   1 
ATOM   210   C CA  . LYS A 1 28  ? 166.715 203.052 196.254 1.00 27.02  ? 49  LYS A CA  1 
ATOM   211   C C   . LYS A 1 28  ? 168.176 202.811 196.606 1.00 27.02  ? 49  LYS A C   1 
ATOM   212   O O   . LYS A 1 28  ? 168.924 202.208 195.833 1.00 27.02  ? 49  LYS A O   1 
ATOM   213   C CB  . LYS A 1 28  ? 165.818 201.989 196.908 1.00 27.02  ? 49  LYS A CB  1 
ATOM   214   C CG  . LYS A 1 28  ? 165.427 202.306 198.346 1.00 27.02  ? 49  LYS A CG  1 
ATOM   215   C CD  . LYS A 1 28  ? 163.960 202.021 198.614 1.00 27.02  ? 49  LYS A CD  1 
ATOM   216   C CE  . LYS A 1 28  ? 163.620 202.231 200.082 1.00 27.02  ? 49  LYS A CE  1 
ATOM   217   N NZ  . LYS A 1 28  ? 163.828 203.641 200.509 1.00 27.02  ? 49  LYS A NZ  1 
ATOM   218   N N   . ASP A 1 29  ? 168.588 203.308 197.769 1.00 31.49  ? 50  ASP A N   1 
ATOM   219   C CA  . ASP A 1 29  ? 169.982 203.259 198.188 1.00 31.49  ? 50  ASP A CA  1 
ATOM   220   C C   . ASP A 1 29  ? 170.121 202.404 199.437 1.00 31.49  ? 50  ASP A C   1 
ATOM   221   O O   . ASP A 1 29  ? 169.389 202.599 200.413 1.00 31.49  ? 50  ASP A O   1 
ATOM   222   C CB  . ASP A 1 29  ? 170.523 204.665 198.450 1.00 31.49  ? 50  ASP A CB  1 
ATOM   223   C CG  . ASP A 1 29  ? 170.846 205.408 197.172 1.00 31.49  ? 50  ASP A CG  1 
ATOM   224   O OD1 . ASP A 1 29  ? 171.519 204.823 196.299 1.00 31.49  ? 50  ASP A OD1 1 
ATOM   225   O OD2 . ASP A 1 29  ? 170.422 206.573 197.037 1.00 31.49  ? 50  ASP A OD2 1 
ATOM   226   N N   . ILE A 1 30  ? 171.060 201.460 199.402 1.00 49.69  ? 51  ILE A N   1 
ATOM   227   C CA  . ILE A 1 30  ? 171.410 200.658 200.564 1.00 49.69  ? 51  ILE A CA  1 
ATOM   228   C C   . ILE A 1 30  ? 172.901 200.826 200.817 1.00 49.69  ? 51  ILE A C   1 
ATOM   229   O O   . ILE A 1 30  ? 173.660 201.265 199.950 1.00 49.69  ? 51  ILE A O   1 
ATOM   230   C CB  . ILE A 1 30  ? 171.056 199.166 200.395 1.00 49.69  ? 51  ILE A CB  1 
ATOM   231   C CG1 . ILE A 1 30  ? 171.836 198.553 199.235 1.00 49.69  ? 51  ILE A CG1 1 
ATOM   232   C CG2 . ILE A 1 30  ? 169.571 198.982 200.176 1.00 49.69  ? 51  ILE A CG2 1 
ATOM   233   C CD1 . ILE A 1 30  ? 171.689 197.053 199.146 1.00 49.69  ? 51  ILE A CD1 1 
ATOM   234   N N   . VAL A 1 31  ? 173.314 200.505 202.038 1.00 29.08  ? 52  VAL A N   1 
ATOM   235   C CA  . VAL A 1 31  ? 174.722 200.510 202.409 1.00 29.08  ? 52  VAL A CA  1 
ATOM   236   C C   . VAL A 1 31  ? 175.068 199.170 203.037 1.00 29.08  ? 52  VAL A C   1 
ATOM   237   O O   . VAL A 1 31  ? 174.298 198.620 203.833 1.00 29.08  ? 52  VAL A O   1 
ATOM   238   C CB  . VAL A 1 31  ? 175.077 201.686 203.347 1.00 29.08  ? 52  VAL A CB  1 
ATOM   239   C CG1 . VAL A 1 31  ? 175.053 202.977 202.580 1.00 29.08  ? 52  VAL A CG1 1 
ATOM   240   C CG2 . VAL A 1 31  ? 174.088 201.795 204.476 1.00 29.08  ? 52  VAL A CG2 1 
ATOM   241   N N   . ILE A 1 32  ? 176.210 198.621 202.640 1.00 49.69  ? 53  ILE A N   1 
ATOM   242   C CA  . ILE A 1 32  ? 176.680 197.332 203.122 1.00 49.69  ? 53  ILE A CA  1 
ATOM   243   C C   . ILE A 1 32  ? 178.016 197.568 203.803 1.00 49.69  ? 53  ILE A C   1 
ATOM   244   O O   . ILE A 1 32  ? 179.008 197.899 203.141 1.00 49.69  ? 53  ILE A O   1 
ATOM   245   C CB  . ILE A 1 32  ? 176.814 196.307 201.990 1.00 49.69  ? 53  ILE A CB  1 
ATOM   246   C CG1 . ILE A 1 32  ? 175.479 196.128 201.274 1.00 49.69  ? 53  ILE A CG1 1 
ATOM   247   C CG2 . ILE A 1 32  ? 177.317 194.981 202.528 1.00 49.69  ? 53  ILE A CG2 1 
ATOM   248   C CD1 . ILE A 1 32  ? 175.600 195.481 199.928 1.00 49.69  ? 53  ILE A CD1 1 
ATOM   249   N N   . LYS A 1 33  ? 178.044 197.417 205.120 1.00 24.88  ? 54  LYS A N   1 
ATOM   250   C CA  . LYS A 1 33  ? 179.310 197.403 205.823 1.00 24.88  ? 54  LYS A CA  1 
ATOM   251   C C   . LYS A 1 33  ? 179.941 196.020 205.699 1.00 24.88  ? 54  LYS A C   1 
ATOM   252   O O   . LYS A 1 33  ? 179.257 195.015 205.496 1.00 24.88  ? 54  LYS A O   1 
ATOM   253   C CB  . LYS A 1 33  ? 179.117 197.797 207.288 1.00 24.88  ? 54  LYS A CB  1 
ATOM   254   C CG  . LYS A 1 33  ? 178.263 196.831 208.098 1.00 24.88  ? 54  LYS A CG  1 
ATOM   255   C CD  . LYS A 1 33  ? 177.754 197.449 209.399 1.00 24.88  ? 54  LYS A CD  1 
ATOM   256   C CE  . LYS A 1 33  ? 178.837 198.231 210.130 1.00 24.88  ? 54  LYS A CE  1 
ATOM   257   N NZ  . LYS A 1 33  ? 179.921 197.336 210.616 1.00 24.88  ? 54  LYS A NZ  1 
ATOM   258   N N   . LEU A 1 34  ? 181.266 195.978 205.782 1.00 22.36  ? 55  LEU A N   1 
ATOM   259   C CA  . LEU A 1 34  ? 181.990 194.727 205.601 1.00 22.36  ? 55  LEU A CA  1 
ATOM   260   C C   . LEU A 1 34  ? 182.655 194.224 206.870 1.00 22.36  ? 55  LEU A C   1 
ATOM   261   O O   . LEU A 1 34  ? 182.700 193.015 207.098 1.00 22.36  ? 55  LEU A O   1 
ATOM   262   C CB  . LEU A 1 34  ? 183.045 194.882 204.499 1.00 22.36  ? 55  LEU A CB  1 
ATOM   263   C CG  . LEU A 1 34  ? 182.526 194.848 203.057 1.00 22.36  ? 55  LEU A CG  1 
ATOM   264   C CD1 . LEU A 1 34  ? 183.668 194.645 202.078 1.00 22.36  ? 55  LEU A CD1 1 
ATOM   265   C CD2 . LEU A 1 34  ? 181.458 193.779 202.856 1.00 22.36  ? 55  LEU A CD2 1 
ATOM   266   N N   . VAL A 1 35  ? 183.160 195.119 207.712 1.00 49.69  ? 56  VAL A N   1 
ATOM   267   C CA  . VAL A 1 35  ? 183.762 194.726 208.982 1.00 49.69  ? 56  VAL A CA  1 
ATOM   268   C C   . VAL A 1 35  ? 182.646 194.540 210.004 1.00 49.69  ? 56  VAL A C   1 
ATOM   269   O O   . VAL A 1 35  ? 181.880 195.482 210.253 1.00 49.69  ? 56  VAL A O   1 
ATOM   270   C CB  . VAL A 1 35  ? 184.787 195.765 209.459 1.00 49.69  ? 56  VAL A CB  1 
ATOM   271   C CG1 . VAL A 1 35  ? 185.250 195.444 210.869 1.00 49.69  ? 56  VAL A CG1 1 
ATOM   272   C CG2 . VAL A 1 35  ? 185.963 195.818 208.505 1.00 49.69  ? 56  VAL A CG2 1 
ATOM   273   N N   . PRO A 1 36  ? 182.502 193.356 210.599 1.00 38.74  ? 57  PRO A N   1 
ATOM   274   C CA  . PRO A 1 36  ? 181.469 193.171 211.625 1.00 38.74  ? 57  PRO A CA  1 
ATOM   275   C C   . PRO A 1 36  ? 181.819 193.912 212.905 1.00 38.74  ? 57  PRO A C   1 
ATOM   276   O O   . PRO A 1 36  ? 182.968 193.915 213.351 1.00 38.74  ? 57  PRO A O   1 
ATOM   277   C CB  . PRO A 1 36  ? 181.451 191.654 211.839 1.00 38.74  ? 57  PRO A CB  1 
ATOM   278   C CG  . PRO A 1 36  ? 182.822 191.211 211.455 1.00 38.74  ? 57  PRO A CG  1 
ATOM   279   C CD  . PRO A 1 36  ? 183.231 192.107 210.319 1.00 38.74  ? 57  PRO A CD  1 
ATOM   280   N N   . ASN A 1 37  ? 180.811 194.547 213.495 1.00 50.31  ? 58  ASN A N   1 
ATOM   281   C CA  . ASN A 1 37  ? 181.005 195.365 214.684 1.00 50.31  ? 58  ASN A CA  1 
ATOM   282   C C   . ASN A 1 37  ? 180.876 194.492 215.923 1.00 50.31  ? 58  ASN A C   1 
ATOM   283   O O   . ASN A 1 37  ? 179.824 193.889 216.160 1.00 50.31  ? 58  ASN A O   1 
ATOM   284   C CB  . ASN A 1 37  ? 179.994 196.509 214.727 1.00 50.31  ? 58  ASN A CB  1 
ATOM   285   C CG  . ASN A 1 37  ? 180.154 197.381 215.958 1.00 50.31  ? 58  ASN A CG  1 
ATOM   286   O OD1 . ASN A 1 37  ? 181.264 197.581 216.452 1.00 50.31  ? 58  ASN A OD1 1 
ATOM   287   N ND2 . ASN A 1 37  ? 179.043 197.905 216.460 1.00 50.31  ? 58  ASN A ND2 1 
ATOM   288   N N   . LEU A 1 38  ? 181.945 194.427 216.711 1.00 67.59  ? 59  LEU A N   1 
ATOM   289   C CA  . LEU A 1 38  ? 181.963 193.669 217.952 1.00 67.59  ? 59  LEU A CA  1 
ATOM   290   C C   . LEU A 1 38  ? 182.236 194.614 219.113 1.00 67.59  ? 59  LEU A C   1 
ATOM   291   O O   . LEU A 1 38  ? 183.151 195.442 219.048 1.00 67.59  ? 59  LEU A O   1 
ATOM   292   C CB  . LEU A 1 38  ? 182.995 192.530 217.881 1.00 67.59  ? 59  LEU A CB  1 
ATOM   293   C CG  . LEU A 1 38  ? 184.488 192.756 217.595 1.00 67.59  ? 59  LEU A CG  1 
ATOM   294   C CD1 . LEU A 1 38  ? 185.326 192.956 218.856 1.00 67.59  ? 59  LEU A CD1 1 
ATOM   295   C CD2 . LEU A 1 38  ? 185.039 191.607 216.765 1.00 67.59  ? 59  LEU A CD2 1 
ATOM   296   N N   . ASN A 1 39  ? 181.415 194.511 220.155 1.00 87.12  ? 60  ASN A N   1 
ATOM   297   C CA  . ASN A 1 39  ? 181.623 195.252 221.391 1.00 87.12  ? 60  ASN A CA  1 
ATOM   298   C C   . ASN A 1 39  ? 181.552 194.383 222.635 1.00 87.12  ? 60  ASN A C   1 
ATOM   299   O O   . ASN A 1 39  ? 182.152 194.751 223.652 1.00 87.12  ? 60  ASN A O   1 
ATOM   300   C CB  . ASN A 1 39  ? 180.602 196.392 221.521 1.00 87.12  ? 60  ASN A CB  1 
ATOM   301   C CG  . ASN A 1 39  ? 180.984 197.609 220.701 1.00 87.12  ? 60  ASN A CG  1 
ATOM   302   O OD1 . ASN A 1 39  ? 182.162 197.940 220.572 1.00 87.12  ? 60  ASN A OD1 1 
ATOM   303   N ND2 . ASN A 1 39  ? 179.985 198.285 220.144 1.00 87.12  ? 60  ASN A ND2 1 
ATOM   304   N N   . ASN A 1 40  ? 180.843 193.254 222.594 1.00 98.94  ? 61  ASN A N   1 
ATOM   305   C CA  . ASN A 1 40  ? 180.909 192.282 223.677 1.00 98.94  ? 61  ASN A CA  1 
ATOM   306   C C   . ASN A 1 40  ? 182.262 191.587 223.730 1.00 98.94  ? 61  ASN A C   1 
ATOM   307   O O   . ASN A 1 40  ? 182.686 191.144 224.803 1.00 98.94  ? 61  ASN A O   1 
ATOM   308   C CB  . ASN A 1 40  ? 179.804 191.237 223.516 1.00 98.94  ? 61  ASN A CB  1 
ATOM   309   C CG  . ASN A 1 40  ? 178.420 191.795 223.789 1.00 98.94  ? 61  ASN A CG  1 
ATOM   310   O OD1 . ASN A 1 40  ? 177.562 191.815 222.906 1.00 98.94  ? 61  ASN A OD1 1 
ATOM   311   N ND2 . ASN A 1 40  ? 178.196 192.245 225.018 1.00 98.94  ? 61  ASN A ND2 1 
ATOM   312   N N   . LEU A 1 41  ? 182.954 191.493 222.592 1.00 92.12  ? 62  LEU A N   1 
ATOM   313   C CA  . LEU A 1 41  ? 184.217 190.773 222.485 1.00 92.12  ? 62  LEU A CA  1 
ATOM   314   C C   . LEU A 1 41  ? 185.428 191.661 222.742 1.00 92.12  ? 62  LEU A C   1 
ATOM   315   O O   . LEU A 1 41  ? 186.516 191.381 222.225 1.00 92.12  ? 62  LEU A O   1 
ATOM   316   C CB  . LEU A 1 41  ? 184.329 190.112 221.110 1.00 92.12  ? 62  LEU A CB  1 
ATOM   317   C CG  . LEU A 1 41  ? 183.870 188.658 220.983 1.00 92.12  ? 62  LEU A CG  1 
ATOM   318   C CD1 . LEU A 1 41  ? 182.353 188.552 220.972 1.00 92.12  ? 62  LEU A CD1 1 
ATOM   319   C CD2 . LEU A 1 41  ? 184.461 188.036 219.730 1.00 92.12  ? 62  LEU A CD2 1 
ATOM   320   N N   . THR A 1 42  ? 185.278 192.721 223.534 1.00 91.75  ? 63  THR A N   1 
ATOM   321   C CA  . THR A 1 42  ? 186.410 193.581 223.855 1.00 91.75  ? 63  THR A CA  1 
ATOM   322   C C   . THR A 1 42  ? 187.360 192.962 224.874 1.00 91.75  ? 63  THR A C   1 
ATOM   323   O O   . THR A 1 42  ? 188.445 193.510 225.094 1.00 91.75  ? 63  THR A O   1 
ATOM   324   C CB  . THR A 1 42  ? 185.915 194.936 224.370 1.00 91.75  ? 63  THR A CB  1 
ATOM   325   O OG1 . THR A 1 42  ? 187.025 195.833 224.502 1.00 91.75  ? 63  THR A OG1 1 
ATOM   326   C CG2 . THR A 1 42  ? 185.229 194.781 225.719 1.00 91.75  ? 63  THR A CG2 1 
ATOM   327   N N   . VAL A 1 43  ? 186.987 191.847 225.495 1.00 94.12  ? 64  VAL A N   1 
ATOM   328   C CA  . VAL A 1 43  ? 187.840 191.195 226.483 1.00 94.12  ? 64  VAL A CA  1 
ATOM   329   C C   . VAL A 1 43  ? 188.785 190.195 225.830 1.00 94.12  ? 64  VAL A C   1 
ATOM   330   O O   . VAL A 1 43  ? 190.003 190.264 226.016 1.00 94.12  ? 64  VAL A O   1 
ATOM   331   C CB  . VAL A 1 43  ? 186.968 190.523 227.566 1.00 94.12  ? 64  VAL A CB  1 
ATOM   332   C CG1 . VAL A 1 43  ? 187.837 189.752 228.547 1.00 94.12  ? 64  VAL A CG1 1 
ATOM   333   C CG2 . VAL A 1 43  ? 186.127 191.563 228.290 1.00 94.12  ? 64  VAL A CG2 1 
ATOM   334   N N   . CYS A 1 44  ? 188.250 189.250 225.054 1.00 103.33 ? 65  CYS A N   1 
ATOM   335   C CA  . CYS A 1 44  ? 189.045 188.177 224.451 1.00 103.33 ? 65  CYS A CA  1 
ATOM   336   C C   . CYS A 1 44  ? 188.732 188.066 222.960 1.00 103.33 ? 65  CYS A C   1 
ATOM   337   O O   . CYS A 1 44  ? 187.957 187.202 222.542 1.00 103.33 ? 65  CYS A O   1 
ATOM   338   C CB  . CYS A 1 44  ? 188.791 186.853 225.164 1.00 103.33 ? 65  CYS A CB  1 
ATOM   339   S SG  . CYS A 1 44  ? 189.603 186.678 226.762 1.00 103.33 ? 65  CYS A SG  1 
ATOM   340   N N   . SER A 1 45  ? 189.346 188.936 222.160 1.00 105.88 ? 66  SER A N   1 
ATOM   341   C CA  . SER A 1 45  ? 189.343 188.774 220.711 1.00 105.88 ? 66  SER A CA  1 
ATOM   342   C C   . SER A 1 45  ? 190.703 188.999 220.075 1.00 105.88 ? 66  SER A C   1 
ATOM   343   O O   . SER A 1 45  ? 190.857 188.678 218.891 1.00 105.88 ? 66  SER A O   1 
ATOM   344   C CB  . SER A 1 45  ? 188.331 189.725 220.060 1.00 105.88 ? 66  SER A CB  1 
ATOM   345   O OG  . SER A 1 45  ? 188.393 191.013 220.647 1.00 105.88 ? 66  SER A OG  1 
ATOM   346   N N   . GLU A 1 46  ? 191.678 189.531 220.811 1.00 105.74 ? 67  GLU A N   1 
ATOM   347   C CA  . GLU A 1 46  ? 193.035 189.904 220.379 1.00 105.74 ? 67  GLU A CA  1 
ATOM   348   C C   . GLU A 1 46  ? 192.928 190.906 219.224 1.00 105.74 ? 67  GLU A C   1 
ATOM   349   O O   . GLU A 1 46  ? 191.978 191.697 219.156 1.00 105.74 ? 67  GLU A O   1 
ATOM   350   C CB  . GLU A 1 46  ? 193.859 188.660 220.071 1.00 105.74 ? 67  GLU A CB  1 
ATOM   351   C CG  . GLU A 1 46  ? 194.467 187.998 221.297 1.00 105.74 ? 67  GLU A CG  1 
ATOM   352   C CD  . GLU A 1 46  ? 193.554 186.958 221.915 1.00 105.74 ? 67  GLU A CD  1 
ATOM   353   O OE1 . GLU A 1 46  ? 192.495 186.665 221.321 1.00 105.74 ? 67  GLU A OE1 1 
ATOM   354   O OE2 . GLU A 1 46  ? 193.898 186.428 222.993 1.00 105.74 ? 67  GLU A OE2 1 
ATOM   355   N N   . MET A 1 47  ? 193.901 190.890 218.319 1.00 106.44 ? 68  MET A N   1 
ATOM   356   C CA  . MET A 1 47  ? 193.931 191.769 217.156 1.00 106.44 ? 68  MET A CA  1 
ATOM   357   C C   . MET A 1 47  ? 193.711 190.982 215.867 1.00 106.44 ? 68  MET A C   1 
ATOM   358   O O   . MET A 1 47  ? 194.367 191.223 214.853 1.00 106.44 ? 68  MET A O   1 
ATOM   359   C CB  . MET A 1 47  ? 195.245 192.542 217.098 1.00 106.44 ? 68  MET A CB  1 
ATOM   360   C CG  . MET A 1 47  ? 195.310 193.899 217.838 1.00 106.44 ? 68  MET A CG  1 
ATOM   361   S SD  . MET A 1 47  ? 194.096 195.201 217.463 1.00 106.44 ? 68  MET A SD  1 
ATOM   362   C CE  . MET A 1 47  ? 192.745 194.909 218.612 1.00 106.44 ? 68  MET A CE  1 
ATOM   363   N N   . SER A 1 48  ? 192.777 190.028 215.899 1.00 86.58  ? 69  SER A N   1 
ATOM   364   C CA  . SER A 1 48  ? 192.505 189.174 214.747 1.00 86.58  ? 69  SER A CA  1 
ATOM   365   C C   . SER A 1 48  ? 191.769 189.895 213.623 1.00 86.58  ? 69  SER A C   1 
ATOM   366   O O   . SER A 1 48  ? 191.663 189.341 212.524 1.00 86.58  ? 69  SER A O   1 
ATOM   367   C CB  . SER A 1 48  ? 191.700 187.951 215.187 1.00 86.58  ? 69  SER A CB  1 
ATOM   368   O OG  . SER A 1 48  ? 192.453 187.138 216.070 1.00 86.58  ? 69  SER A OG  1 
ATOM   369   N N   . ILE A 1 49  ? 191.261 191.104 213.867 1.00 64.56  ? 70  ILE A N   1 
ATOM   370   C CA  . ILE A 1 49  ? 190.608 191.881 212.819 1.00 64.56  ? 70  ILE A CA  1 
ATOM   371   C C   . ILE A 1 49  ? 191.626 192.446 211.828 1.00 64.56  ? 70  ILE A C   1 
ATOM   372   O O   . ILE A 1 49  ? 191.263 192.760 210.686 1.00 64.56  ? 70  ILE A O   1 
ATOM   373   C CB  . ILE A 1 49  ? 189.760 192.990 213.475 1.00 64.56  ? 70  ILE A CB  1 
ATOM   374   C CG1 . ILE A 1 49  ? 188.990 192.432 214.675 1.00 64.56  ? 70  ILE A CG1 1 
ATOM   375   C CG2 . ILE A 1 49  ? 188.742 193.590 212.503 1.00 64.56  ? 70  ILE A CG2 1 
ATOM   376   C CD1 . ILE A 1 49  ? 187.927 191.396 214.321 1.00 64.56  ? 70  ILE A CD1 1 
ATOM   377   N N   . ASP A 1 50  ? 192.902 192.542 212.228 1.00 57.69  ? 71  ASP A N   1 
ATOM   378   C CA  . ASP A 1 50  ? 193.928 193.176 211.400 1.00 57.69  ? 71  ASP A CA  1 
ATOM   379   C C   . ASP A 1 50  ? 194.227 192.370 210.139 1.00 57.69  ? 71  ASP A C   1 
ATOM   380   O O   . ASP A 1 50  ? 194.451 192.949 209.068 1.00 57.69  ? 71  ASP A O   1 
ATOM   381   C CB  . ASP A 1 50  ? 195.201 193.373 212.222 1.00 57.69  ? 71  ASP A CB  1 
ATOM   382   C CG  . ASP A 1 50  ? 196.082 194.479 211.678 1.00 57.69  ? 71  ASP A CG  1 
ATOM   383   O OD1 . ASP A 1 50  ? 195.666 195.159 210.718 1.00 57.69  ? 71  ASP A OD1 1 
ATOM   384   O OD2 . ASP A 1 50  ? 197.194 194.668 212.214 1.00 57.69  ? 71  ASP A OD2 1 
ATOM   385   N N   . GLY A 1 51  ? 194.228 191.038 210.244 1.00 39.57  ? 72  GLY A N   1 
ATOM   386   C CA  . GLY A 1 51  ? 194.416 190.209 209.062 1.00 39.57  ? 72  GLY A CA  1 
ATOM   387   C C   . GLY A 1 51  ? 193.260 190.312 208.085 1.00 39.57  ? 72  GLY A C   1 
ATOM   388   O O   . GLY A 1 51  ? 193.465 190.334 206.866 1.00 39.57  ? 72  GLY A O   1 
ATOM   389   N N   . TYR A 1 52  ? 192.033 190.407 208.605 1.00 33.01  ? 73  TYR A N   1 
ATOM   390   C CA  . TYR A 1 52  ? 190.868 190.611 207.751 1.00 33.01  ? 73  TYR A CA  1 
ATOM   391   C C   . TYR A 1 52  ? 190.901 191.981 207.081 1.00 33.01  ? 73  TYR A C   1 
ATOM   392   O O   . TYR A 1 52  ? 190.509 192.113 205.915 1.00 33.01  ? 73  TYR A O   1 
ATOM   393   C CB  . TYR A 1 52  ? 189.588 190.440 208.566 1.00 33.01  ? 73  TYR A CB  1 
ATOM   394   C CG  . TYR A 1 52  ? 188.328 190.471 207.736 1.00 33.01  ? 73  TYR A CG  1 
ATOM   395   C CD1 . TYR A 1 52  ? 188.132 189.560 206.706 1.00 33.01  ? 73  TYR A CD1 1 
ATOM   396   C CD2 . TYR A 1 52  ? 187.334 191.411 207.981 1.00 33.01  ? 73  TYR A CD2 1 
ATOM   397   C CE1 . TYR A 1 52  ? 186.980 189.585 205.941 1.00 33.01  ? 73  TYR A CE1 1 
ATOM   398   C CE2 . TYR A 1 52  ? 186.178 191.443 207.221 1.00 33.01  ? 73  TYR A CE2 1 
ATOM   399   C CZ  . TYR A 1 52  ? 186.009 190.527 206.203 1.00 33.01  ? 73  TYR A CZ  1 
ATOM   400   O OH  . TYR A 1 52  ? 184.864 190.551 205.444 1.00 33.01  ? 73  TYR A OH  1 
ATOM   401   N N   . LEU A 1 53  ? 191.371 193.006 207.802 1.00 34.70  ? 74  LEU A N   1 
ATOM   402   C CA  . LEU A 1 53  ? 191.519 194.337 207.217 1.00 34.70  ? 74  LEU A CA  1 
ATOM   403   C C   . LEU A 1 53  ? 192.571 194.350 206.115 1.00 34.70  ? 74  LEU A C   1 
ATOM   404   O O   . LEU A 1 53  ? 192.372 194.972 205.063 1.00 34.70  ? 74  LEU A O   1 
ATOM   405   C CB  . LEU A 1 53  ? 191.877 195.352 208.301 1.00 34.70  ? 74  LEU A CB  1 
ATOM   406   C CG  . LEU A 1 53  ? 190.761 195.751 209.264 1.00 34.70  ? 74  LEU A CG  1 
ATOM   407   C CD1 . LEU A 1 53  ? 191.308 196.614 210.388 1.00 34.70  ? 74  LEU A CD1 1 
ATOM   408   C CD2 . LEU A 1 53  ? 189.665 196.481 208.514 1.00 34.70  ? 74  LEU A CD2 1 
ATOM   409   N N   . ASN A 1 54  ? 193.692 193.654 206.333 1.00 30.84  ? 75  ASN A N   1 
ATOM   410   C CA  . ASN A 1 54  ? 194.720 193.552 205.302 1.00 30.84  ? 75  ASN A CA  1 
ATOM   411   C C   . ASN A 1 54  ? 194.249 192.719 204.116 1.00 30.84  ? 75  ASN A C   1 
ATOM   412   O O   . ASN A 1 54  ? 194.740 192.906 202.997 1.00 30.84  ? 75  ASN A O   1 
ATOM   413   C CB  . ASN A 1 54  ? 195.998 192.957 205.891 1.00 30.84  ? 75  ASN A CB  1 
ATOM   414   C CG  . ASN A 1 54  ? 196.915 194.011 206.476 1.00 30.84  ? 75  ASN A CG  1 
ATOM   415   O OD1 . ASN A 1 54  ? 196.653 195.208 206.365 1.00 30.84  ? 75  ASN A OD1 1 
ATOM   416   N ND2 . ASN A 1 54  ? 197.997 193.570 207.106 1.00 30.84  ? 75  ASN A ND2 1 
ATOM   417   N N   . LEU A 1 55  ? 193.312 191.796 204.339 1.00 24.34  ? 76  LEU A N   1 
ATOM   418   C CA  . LEU A 1 55  ? 192.748 191.042 203.225 1.00 24.34  ? 76  LEU A CA  1 
ATOM   419   C C   . LEU A 1 55  ? 191.771 191.887 202.410 1.00 24.34  ? 76  LEU A C   1 
ATOM   420   O O   . LEU A 1 55  ? 191.774 191.825 201.176 1.00 24.34  ? 76  LEU A O   1 
ATOM   421   C CB  . LEU A 1 55  ? 192.065 189.778 203.742 1.00 24.34  ? 76  LEU A CB  1 
ATOM   422   C CG  . LEU A 1 55  ? 192.981 188.567 203.924 1.00 24.34  ? 76  LEU A CG  1 
ATOM   423   C CD1 . LEU A 1 55  ? 192.220 187.402 204.536 1.00 24.34  ? 76  LEU A CD1 1 
ATOM   424   C CD2 . LEU A 1 55  ? 193.626 188.165 202.608 1.00 24.34  ? 76  LEU A CD2 1 
ATOM   425   N N   . ILE A 1 56  ? 190.926 192.684 203.077 1.00 24.55  ? 77  ILE A N   1 
ATOM   426   C CA  . ILE A 1 56  ? 189.894 193.442 202.364 1.00 24.55  ? 77  ILE A CA  1 
ATOM   427   C C   . ILE A 1 56  ? 190.373 194.793 201.847 1.00 24.55  ? 77  ILE A C   1 
ATOM   428   O O   . ILE A 1 56  ? 189.650 195.434 201.063 1.00 24.55  ? 77  ILE A O   1 
ATOM   429   C CB  . ILE A 1 56  ? 188.641 193.673 203.233 1.00 24.55  ? 77  ILE A CB  1 
ATOM   430   C CG1 . ILE A 1 56  ? 188.958 194.599 204.407 1.00 24.55  ? 77  ILE A CG1 1 
ATOM   431   C CG2 . ILE A 1 56  ? 188.053 192.349 203.697 1.00 24.55  ? 77  ILE A CG2 1 
ATOM   432   C CD1 . ILE A 1 56  ? 187.733 195.121 205.114 1.00 24.55  ? 77  ILE A CD1 1 
ATOM   433   N N   . ASN A 1 57  ? 191.557 195.257 202.261 1.00 24.06  ? 78  ASN A N   1 
ATOM   434   C CA  . ASN A 1 57  ? 192.099 196.480 201.679 1.00 24.06  ? 78  ASN A CA  1 
ATOM   435   C C   . ASN A 1 57  ? 192.552 196.285 200.239 1.00 24.06  ? 78  ASN A C   1 
ATOM   436   O O   . ASN A 1 57  ? 192.636 197.266 199.493 1.00 24.06  ? 78  ASN A O   1 
ATOM   437   C CB  . ASN A 1 57  ? 193.260 197.004 202.523 1.00 24.06  ? 78  ASN A CB  1 
ATOM   438   C CG  . ASN A 1 57  ? 192.794 197.835 203.700 1.00 24.06  ? 78  ASN A CG  1 
ATOM   439   O OD1 . ASN A 1 57  ? 191.843 198.608 203.590 1.00 24.06  ? 78  ASN A OD1 1 
ATOM   440   N ND2 . ASN A 1 57  ? 193.464 197.682 204.835 1.00 24.06  ? 78  ASN A ND2 1 
ATOM   441   N N   . ALA A 1 58  ? 192.840 195.050 199.829 1.00 23.65  ? 79  ALA A N   1 
ATOM   442   C CA  . ALA A 1 58  ? 193.120 194.764 198.429 1.00 23.65  ? 79  ALA A CA  1 
ATOM   443   C C   . ALA A 1 58  ? 191.860 194.706 197.578 1.00 23.65  ? 79  ALA A C   1 
ATOM   444   O O   . ALA A 1 58  ? 191.961 194.700 196.347 1.00 23.65  ? 79  ALA A O   1 
ATOM   445   C CB  . ALA A 1 58  ? 193.885 193.444 198.303 1.00 23.65  ? 79  ALA A CB  1 
ATOM   446   N N   . VAL A 1 59  ? 190.686 194.664 198.201 1.00 24.06  ? 80  VAL A N   1 
ATOM   447   C CA  . VAL A 1 59  ? 189.419 194.641 197.488 1.00 24.06  ? 80  VAL A CA  1 
ATOM   448   C C   . VAL A 1 59  ? 188.786 196.026 197.428 1.00 24.06  ? 80  VAL A C   1 
ATOM   449   O O   . VAL A 1 59  ? 188.286 196.437 196.381 1.00 24.06  ? 80  VAL A O   1 
ATOM   450   C CB  . VAL A 1 59  ? 188.467 193.620 198.150 1.00 24.06  ? 80  VAL A CB  1 
ATOM   451   C CG1 . VAL A 1 59  ? 187.140 193.538 197.408 1.00 24.06  ? 80  VAL A CG1 1 
ATOM   452   C CG2 . VAL A 1 59  ? 189.124 192.253 198.227 1.00 24.06  ? 80  VAL A CG2 1 
ATOM   453   N N   . ILE A 1 60  ? 188.823 196.761 198.543 1.00 23.45  ? 81  ILE A N   1 
ATOM   454   C CA  . ILE A 1 60  ? 188.076 198.015 198.643 1.00 23.45  ? 81  ILE A CA  1 
ATOM   455   C C   . ILE A 1 60  ? 188.754 199.126 197.836 1.00 23.45  ? 81  ILE A C   1 
ATOM   456   O O   . ILE A 1 60  ? 188.091 199.861 197.093 1.00 23.45  ? 81  ILE A O   1 
ATOM   457   C CB  . ILE A 1 60  ? 187.895 198.397 200.125 1.00 23.45  ? 81  ILE A CB  1 
ATOM   458   C CG1 . ILE A 1 60  ? 186.799 197.539 200.756 1.00 23.45  ? 81  ILE A CG1 1 
ATOM   459   C CG2 . ILE A 1 60  ? 187.527 199.856 200.292 1.00 23.45  ? 81  ILE A CG2 1 
ATOM   460   C CD1 . ILE A 1 60  ? 186.694 197.694 202.255 1.00 23.45  ? 81  ILE A CD1 1 
ATOM   461   N N   . ILE A 1 61  ? 190.086 199.238 197.948 1.00 24.57  ? 82  ILE A N   1 
ATOM   462   C CA  . ILE A 1 61  ? 190.795 200.425 197.438 1.00 24.57  ? 82  ILE A CA  1 
ATOM   463   C C   . ILE A 1 61  ? 190.782 200.573 195.911 1.00 24.57  ? 82  ILE A C   1 
ATOM   464   O O   . ILE A 1 61  ? 190.509 201.689 195.432 1.00 24.57  ? 82  ILE A O   1 
ATOM   465   C CB  . ILE A 1 61  ? 192.208 200.491 198.047 1.00 24.57  ? 82  ILE A CB  1 
ATOM   466   C CG1 . ILE A 1 61  ? 192.126 200.585 199.570 1.00 24.57  ? 82  ILE A CG1 1 
ATOM   467   C CG2 . ILE A 1 61  ? 193.007 201.669 197.506 1.00 24.57  ? 82  ILE A CG2 1 
ATOM   468   C CD1 . ILE A 1 61  ? 193.463 200.441 200.259 1.00 24.57  ? 82  ILE A CD1 1 
ATOM   469   N N   . PRO A 1 62  ? 191.074 199.525 195.087 1.00 23.62  ? 83  PRO A N   1 
ATOM   470   C CA  . PRO A 1 62  ? 190.991 199.735 193.622 1.00 23.62  ? 83  PRO A CA  1 
ATOM   471   C C   . PRO A 1 62  ? 189.599 200.068 193.102 1.00 23.62  ? 83  PRO A C   1 
ATOM   472   O O   . PRO A 1 62  ? 189.477 200.774 192.086 1.00 23.62  ? 83  PRO A O   1 
ATOM   473   C CB  . PRO A 1 62  ? 191.480 198.399 193.051 1.00 23.62  ? 83  PRO A CB  1 
ATOM   474   C CG  . PRO A 1 62  ? 192.377 197.880 194.064 1.00 23.62  ? 83  PRO A CG  1 
ATOM   475   C CD  . PRO A 1 62  ? 191.681 198.198 195.344 1.00 23.62  ? 83  PRO A CD  1 
ATOM   476   N N   . ILE A 1 63  ? 188.556 199.596 193.790 1.00 23.32  ? 84  ILE A N   1 
ATOM   477   C CA  . ILE A 1 63  ? 187.186 199.979 193.464 1.00 23.32  ? 84  ILE A CA  1 
ATOM   478   C C   . ILE A 1 63  ? 186.996 201.480 193.650 1.00 23.32  ? 84  ILE A C   1 
ATOM   479   O O   . ILE A 1 63  ? 186.446 202.162 192.776 1.00 23.32  ? 84  ILE A O   1 
ATOM   480   C CB  . ILE A 1 63  ? 186.192 199.169 194.318 1.00 23.32  ? 84  ILE A CB  1 
ATOM   481   C CG1 . ILE A 1 63  ? 186.313 197.675 193.999 1.00 23.32  ? 84  ILE A CG1 1 
ATOM   482   C CG2 . ILE A 1 63  ? 184.767 199.660 194.100 1.00 23.32  ? 84  ILE A CG2 1 
ATOM   483   C CD1 . ILE A 1 63  ? 185.208 196.807 194.583 1.00 23.32  ? 84  ILE A CD1 1 
ATOM   484   N N   . SER A 1 64  ? 187.503 202.018 194.766 1.00 21.13  ? 85  SER A N   1 
ATOM   485   C CA  . SER A 1 64  ? 187.409 203.451 195.032 1.00 21.13  ? 85  SER A CA  1 
ATOM   486   C C   . SER A 1 64  ? 188.216 204.264 194.029 1.00 21.13  ? 85  SER A C   1 
ATOM   487   O O   . SER A 1 64  ? 187.773 205.338 193.602 1.00 21.13  ? 85  SER A O   1 
ATOM   488   C CB  . SER A 1 64  ? 187.875 203.753 196.455 1.00 21.13  ? 85  SER A CB  1 
ATOM   489   O OG  . SER A 1 64  ? 187.898 205.149 196.692 1.00 21.13  ? 85  SER A OG  1 
ATOM   490   N N   . GLN A 1 65  ? 189.394 203.760 193.635 1.00 24.47  ? 86  GLN A N   1 
ATOM   491   C CA  . GLN A 1 65  ? 190.224 204.444 192.640 1.00 24.47  ? 86  GLN A CA  1 
ATOM   492   C C   . GLN A 1 65  ? 189.528 204.525 191.284 1.00 24.47  ? 86  GLN A C   1 
ATOM   493   O O   . GLN A 1 65  ? 189.502 205.590 190.647 1.00 24.47  ? 86  GLN A O   1 
ATOM   494   C CB  . GLN A 1 65  ? 191.569 203.730 192.500 1.00 24.47  ? 86  GLN A CB  1 
ATOM   495   C CG  . GLN A 1 65  ? 192.454 203.789 193.730 1.00 24.47  ? 86  GLN A CG  1 
ATOM   496   C CD  . GLN A 1 65  ? 192.871 205.200 194.078 1.00 24.47  ? 86  GLN A CD  1 
ATOM   497   O OE1 . GLN A 1 65  ? 192.430 205.762 195.081 1.00 24.47  ? 86  GLN A OE1 1 
ATOM   498   N NE2 . GLN A 1 65  ? 193.727 205.784 193.249 1.00 24.47  ? 86  GLN A NE2 1 
ATOM   499   N N   . SER A 1 66  ? 188.940 203.411 190.836 1.00 24.85  ? 87  SER A N   1 
ATOM   500   C CA  . SER A 1 66  ? 188.245 203.409 189.552 1.00 24.85  ? 87  SER A CA  1 
ATOM   501   C C   . SER A 1 66  ? 186.985 204.268 189.595 1.00 24.85  ? 87  SER A C   1 
ATOM   502   O O   . SER A 1 66  ? 186.669 204.962 188.617 1.00 24.85  ? 87  SER A O   1 
ATOM   503   C CB  . SER A 1 66  ? 187.908 201.979 189.139 1.00 24.85  ? 87  SER A CB  1 
ATOM   504   O OG  . SER A 1 66  ? 187.050 201.965 188.012 1.00 24.85  ? 87  SER A OG  1 
ATOM   505   N N   . LEU A 1 67  ? 186.272 204.261 190.730 1.00 24.55  ? 88  LEU A N   1 
ATOM   506   C CA  . LEU A 1 67  ? 185.090 205.109 190.871 1.00 24.55  ? 88  LEU A CA  1 
ATOM   507   C C   . LEU A 1 67  ? 185.445 206.591 190.834 1.00 24.55  ? 88  LEU A C   1 
ATOM   508   O O   . LEU A 1 67  ? 184.779 207.366 190.143 1.00 24.55  ? 88  LEU A O   1 
ATOM   509   C CB  . LEU A 1 67  ? 184.325 204.777 192.153 1.00 24.55  ? 88  LEU A CB  1 
ATOM   510   C CG  . LEU A 1 67  ? 183.519 203.478 192.170 1.00 24.55  ? 88  LEU A CG  1 
ATOM   511   C CD1 . LEU A 1 67  ? 182.919 203.236 193.546 1.00 24.55  ? 88  LEU A CD1 1 
ATOM   512   C CD2 . LEU A 1 67  ? 182.441 203.516 191.111 1.00 24.55  ? 88  LEU A CD2 1 
ATOM   513   N N   . GLU A 1 68  ? 186.507 207.003 191.540 1.00 30.24  ? 89  GLU A N   1 
ATOM   514   C CA  . GLU A 1 68  ? 186.849 208.426 191.545 1.00 30.24  ? 89  GLU A CA  1 
ATOM   515   C C   . GLU A 1 68  ? 187.422 208.863 190.200 1.00 30.24  ? 89  GLU A C   1 
ATOM   516   O O   . GLU A 1 68  ? 187.258 210.023 189.800 1.00 30.24  ? 89  GLU A O   1 
ATOM   517   C CB  . GLU A 1 68  ? 187.805 208.765 192.698 1.00 30.24  ? 89  GLU A CB  1 
ATOM   518   C CG  . GLU A 1 68  ? 189.185 208.115 192.689 1.00 30.24  ? 89  GLU A CG  1 
ATOM   519   C CD  . GLU A 1 68  ? 190.222 208.907 191.922 1.00 30.24  ? 89  GLU A CD  1 
ATOM   520   O OE1 . GLU A 1 68  ? 189.995 210.114 191.696 1.00 30.24  ? 89  GLU A OE1 1 
ATOM   521   O OE2 . GLU A 1 68  ? 191.256 208.320 191.543 1.00 30.24  ? 89  GLU A OE2 1 
ATOM   522   N N   . LEU A 1 69  ? 188.058 207.938 189.468 1.00 30.37  ? 90  LEU A N   1 
ATOM   523   C CA  . LEU A 1 69  ? 188.449 208.236 188.091 1.00 30.37  ? 90  LEU A CA  1 
ATOM   524   C C   . LEU A 1 69  ? 187.219 208.454 187.210 1.00 30.37  ? 90  LEU A C   1 
ATOM   525   O O   . LEU A 1 69  ? 187.195 209.369 186.373 1.00 30.37  ? 90  LEU A O   1 
ATOM   526   C CB  . LEU A 1 69  ? 189.341 207.112 187.550 1.00 30.37  ? 90  LEU A CB  1 
ATOM   527   C CG  . LEU A 1 69  ? 190.109 207.248 186.226 1.00 30.37  ? 90  LEU A CG  1 
ATOM   528   C CD1 . LEU A 1 69  ? 191.391 206.440 186.317 1.00 30.37  ? 90  LEU A CD1 1 
ATOM   529   C CD2 . LEU A 1 69  ? 189.314 206.775 185.012 1.00 30.37  ? 90  LEU A CD2 1 
ATOM   530   N N   . MET A 1 70  ? 186.178 207.633 187.400 1.00 28.97  ? 91  MET A N   1 
ATOM   531   C CA  . MET A 1 70  ? 184.950 207.801 186.622 1.00 28.97  ? 91  MET A CA  1 
ATOM   532   C C   . MET A 1 70  ? 184.213 209.091 186.980 1.00 28.97  ? 91  MET A C   1 
ATOM   533   O O   . MET A 1 70  ? 183.536 209.677 186.128 1.00 28.97  ? 91  MET A O   1 
ATOM   534   C CB  . MET A 1 70  ? 184.035 206.590 186.800 1.00 28.97  ? 91  MET A CB  1 
ATOM   535   C CG  . MET A 1 70  ? 184.545 205.332 186.119 1.00 28.97  ? 91  MET A CG  1 
ATOM   536   S SD  . MET A 1 70  ? 185.397 205.698 184.572 1.00 28.97  ? 91  MET A SD  1 
ATOM   537   C CE  . MET A 1 70  ? 185.382 204.091 183.783 1.00 28.97  ? 91  MET A CE  1 
ATOM   538   N N   . ARG A 1 71  ? 184.314 209.543 188.235 1.00 32.23  ? 92  ARG A N   1 
ATOM   539   C CA  . ARG A 1 71  ? 183.774 210.866 188.558 1.00 32.23  ? 92  ARG A CA  1 
ATOM   540   C C   . ARG A 1 71  ? 184.634 211.974 187.959 1.00 32.23  ? 92  ARG A C   1 
ATOM   541   O O   . ARG A 1 71  ? 184.125 213.053 187.635 1.00 32.23  ? 92  ARG A O   1 
ATOM   542   C CB  . ARG A 1 71  ? 183.633 211.078 190.070 1.00 32.23  ? 92  ARG A CB  1 
ATOM   543   C CG  . ARG A 1 71  ? 183.051 209.924 190.851 1.00 32.23  ? 92  ARG A CG  1 
ATOM   544   C CD  . ARG A 1 71  ? 182.307 210.360 192.094 1.00 32.23  ? 92  ARG A CD  1 
ATOM   545   N NE  . ARG A 1 71  ? 181.498 209.271 192.628 1.00 32.23  ? 92  ARG A NE  1 
ATOM   546   C CZ  . ARG A 1 71  ? 180.180 209.187 192.517 1.00 32.23  ? 92  ARG A CZ  1 
ATOM   547   N NH1 . ARG A 1 71  ? 179.481 210.104 191.870 1.00 32.23  ? 92  ARG A NH1 1 
ATOM   548   N NH2 . ARG A 1 71  ? 179.548 208.151 193.061 1.00 32.23  ? 92  ARG A NH2 1 
ATOM   549   N N   . ASN A 1 72  ? 185.943 211.736 187.819 1.00 45.93  ? 93  ASN A N   1 
ATOM   550   C CA  . ASN A 1 72  ? 186.807 212.752 187.221 1.00 45.93  ? 93  ASN A CA  1 
ATOM   551   C C   . ASN A 1 72  ? 186.588 212.884 185.717 1.00 45.93  ? 93  ASN A C   1 
ATOM   552   O O   . ASN A 1 72  ? 186.866 213.945 185.146 1.00 45.93  ? 93  ASN A O   1 
ATOM   553   C CB  . ASN A 1 72  ? 188.277 212.453 187.503 1.00 45.93  ? 93  ASN A CB  1 
ATOM   554   C CG  . ASN A 1 72  ? 188.836 213.297 188.626 1.00 45.93  ? 93  ASN A CG  1 
ATOM   555   O OD1 . ASN A 1 72  ? 188.228 214.290 189.023 1.00 45.93  ? 93  ASN A OD1 1 
ATOM   556   N ND2 . ASN A 1 72  ? 190.023 212.921 189.116 1.00 45.93  ? 93  ASN A ND2 1 
ATOM   557   N N   . ASN A 1 73  ? 186.130 211.817 185.052 1.00 40.50  ? 94  ASN A N   1 
ATOM   558   C CA  . ASN A 1 73  ? 185.934 211.887 183.602 1.00 40.50  ? 94  ASN A CA  1 
ATOM   559   C C   . ASN A 1 73  ? 184.779 212.812 183.224 1.00 40.50  ? 94  ASN A C   1 
ATOM   560   O O   . ASN A 1 73  ? 184.867 213.559 182.243 1.00 40.50  ? 94  ASN A O   1 
ATOM   561   C CB  . ASN A 1 73  ? 185.716 210.490 183.020 1.00 40.50  ? 94  ASN A CB  1 
ATOM   562   C CG  . ASN A 1 73  ? 186.876 209.559 183.292 1.00 40.50  ? 94  ASN A CG  1 
ATOM   563   O OD1 . ASN A 1 73  ? 187.986 210.004 183.583 1.00 40.50  ? 94  ASN A OD1 1 
ATOM   564   N ND2 . ASN A 1 73  ? 186.628 208.259 183.196 1.00 40.50  ? 94  ASN A ND2 1 
ATOM   565   N N   . VAL A 1 74  ? 183.686 212.775 183.983 1.00 46.70  ? 95  VAL A N   1 
ATOM   566   C CA  . VAL A 1 74  ? 182.540 213.637 183.706 1.00 46.70  ? 95  VAL A CA  1 
ATOM   567   C C   . VAL A 1 74  ? 182.863 215.037 184.230 1.00 46.70  ? 95  VAL A C   1 
ATOM   568   O O   . VAL A 1 74  ? 183.684 215.193 185.141 1.00 46.70  ? 95  VAL A O   1 
ATOM   569   C CB  . VAL A 1 74  ? 181.252 213.040 184.319 1.00 46.70  ? 95  VAL A CB  1 
ATOM   570   C CG1 . VAL A 1 74  ? 181.276 213.085 185.842 1.00 46.70  ? 95  VAL A CG1 1 
ATOM   571   C CG2 . VAL A 1 74  ? 179.980 213.669 183.739 1.00 46.70  ? 95  VAL A CG2 1 
ATOM   572   N N   . LYS A 1 75  ? 182.261 216.069 183.635 1.00 57.06  ? 96  LYS A N   1 
ATOM   573   C CA  . LYS A 1 75  ? 182.575 217.450 184.002 1.00 57.06  ? 96  LYS A CA  1 
ATOM   574   C C   . LYS A 1 75  ? 181.302 218.279 183.892 1.00 57.06  ? 96  LYS A C   1 
ATOM   575   O O   . LYS A 1 75  ? 180.752 218.419 182.797 1.00 57.06  ? 96  LYS A O   1 
ATOM   576   C CB  . LYS A 1 75  ? 183.674 218.009 183.105 1.00 57.06  ? 96  LYS A CB  1 
ATOM   577   C CG  . LYS A 1 75  ? 183.837 219.521 183.175 1.00 57.06  ? 96  LYS A CG  1 
ATOM   578   C CD  . LYS A 1 75  ? 185.244 219.948 182.793 1.00 57.06  ? 96  LYS A CD  1 
ATOM   579   C CE  . LYS A 1 75  ? 185.408 220.019 181.282 1.00 57.06  ? 96  LYS A CE  1 
ATOM   580   N NZ  . LYS A 1 75  ? 184.911 221.309 180.726 1.00 57.06  ? 96  LYS A NZ  1 
ATOM   581   N N   . ASP A 1 76  ? 180.840 218.826 185.013 1.00 64.12  ? 97  ASP A N   1 
ATOM   582   C CA  . ASP A 1 76  ? 179.633 219.644 185.000 1.00 64.12  ? 97  ASP A CA  1 
ATOM   583   C C   . ASP A 1 76  ? 179.932 221.011 184.396 1.00 64.12  ? 97  ASP A C   1 
ATOM   584   O O   . ASP A 1 76  ? 180.723 221.784 184.946 1.00 64.12  ? 97  ASP A O   1 
ATOM   585   C CB  . ASP A 1 76  ? 179.085 219.791 186.419 1.00 64.12  ? 97  ASP A CB  1 
ATOM   586   C CG  . ASP A 1 76  ? 177.591 220.058 186.446 1.00 64.12  ? 97  ASP A CG  1 
ATOM   587   O OD1 . ASP A 1 76  ? 177.014 220.358 185.381 1.00 64.12  ? 97  ASP A OD1 1 
ATOM   588   O OD2 . ASP A 1 76  ? 176.992 219.965 187.538 1.00 64.12  ? 97  ASP A OD2 1 
ATOM   589   N N   . GLY A 1 77  ? 179.297 221.307 183.267 1.00 91.81  ? 98  GLY A N   1 
ATOM   590   C CA  . GLY A 1 77  ? 179.520 222.569 182.582 1.00 91.81  ? 98  GLY A CA  1 
ATOM   591   C C   . GLY A 1 77  ? 178.413 222.828 181.586 1.00 91.81  ? 98  GLY A C   1 
ATOM   592   O O   . GLY A 1 77  ? 177.455 222.059 181.474 1.00 91.81  ? 98  GLY A O   1 
ATOM   593   N N   . THR A 1 78  ? 178.563 223.932 180.854 1.00 109.45 ? 99  THR A N   1 
ATOM   594   C CA  . THR A 1 78  ? 177.569 224.366 179.869 1.00 109.45 ? 99  THR A CA  1 
ATOM   595   C C   . THR A 1 78  ? 178.201 225.175 178.737 1.00 109.45 ? 99  THR A C   1 
ATOM   596   O O   . THR A 1 78  ? 178.438 226.384 178.850 1.00 109.45 ? 99  THR A O   1 
ATOM   597   C CB  . THR A 1 78  ? 176.415 225.114 180.558 1.00 109.45 ? 99  THR A CB  1 
ATOM   598   O OG1 . THR A 1 78  ? 175.519 225.663 179.580 1.00 109.45 ? 99  THR A OG1 1 
ATOM   599   C CG2 . THR A 1 78  ? 176.873 226.158 181.613 1.00 109.45 ? 99  THR A CG2 1 
ATOM   600   N N   . PRO A 1 79  ? 178.518 224.518 177.618 1.00 110.81 ? 100 PRO A N   1 
ATOM   601   C CA  . PRO A 1 79  ? 178.839 225.267 176.396 1.00 110.81 ? 100 PRO A CA  1 
ATOM   602   C C   . PRO A 1 79  ? 177.613 225.966 175.832 1.00 110.81 ? 100 PRO A C   1 
ATOM   603   O O   . PRO A 1 79  ? 176.711 225.300 175.311 1.00 110.81 ? 100 PRO A O   1 
ATOM   604   C CB  . PRO A 1 79  ? 179.351 224.181 175.443 1.00 110.81 ? 100 PRO A CB  1 
ATOM   605   C CG  . PRO A 1 79  ? 179.880 223.120 176.335 1.00 110.81 ? 100 PRO A CG  1 
ATOM   606   C CD  . PRO A 1 79  ? 178.992 223.125 177.551 1.00 110.81 ? 100 PRO A CD  1 
ATOM   607   N N   . ASN A 1 80  ? 177.605 227.304 175.910 1.00 116.52 ? 101 ASN A N   1 
ATOM   608   C CA  . ASN A 1 80  ? 176.500 228.186 175.529 1.00 116.52 ? 101 ASN A CA  1 
ATOM   609   C C   . ASN A 1 80  ? 175.170 227.774 176.155 1.00 116.52 ? 101 ASN A C   1 
ATOM   610   O O   . ASN A 1 80  ? 175.096 227.532 177.364 1.00 116.52 ? 101 ASN A O   1 
ATOM   611   C CB  . ASN A 1 80  ? 176.373 228.254 174.002 1.00 116.52 ? 101 ASN A CB  1 
ATOM   612   C CG  . ASN A 1 80  ? 177.592 228.870 173.343 1.00 116.52 ? 101 ASN A CG  1 
ATOM   613   O OD1 . ASN A 1 80  ? 178.323 228.200 172.613 1.00 116.52 ? 101 ASN A OD1 1 
ATOM   614   N ND2 . ASN A 1 80  ? 177.819 230.152 173.601 1.00 116.52 ? 101 ASN A ND2 1 
ATOM   615   N N   . GLU A 1 81  ? 174.117 227.685 175.340 1.00 111.49 ? 102 GLU A N   1 
ATOM   616   C CA  . GLU A 1 81  ? 172.782 227.322 175.820 1.00 111.49 ? 102 GLU A CA  1 
ATOM   617   C C   . GLU A 1 81  ? 172.639 225.799 175.802 1.00 111.49 ? 102 GLU A C   1 
ATOM   618   O O   . GLU A 1 81  ? 172.078 225.195 174.885 1.00 111.49 ? 102 GLU A O   1 
ATOM   619   C CB  . GLU A 1 81  ? 171.702 227.995 174.982 1.00 111.49 ? 102 GLU A CB  1 
ATOM   620   C CG  . GLU A 1 81  ? 171.639 229.516 175.105 1.00 111.49 ? 102 GLU A CG  1 
ATOM   621   C CD  . GLU A 1 81  ? 172.596 230.233 174.167 1.00 111.49 ? 102 GLU A CD  1 
ATOM   622   O OE1 . GLU A 1 81  ? 173.269 229.554 173.363 1.00 111.49 ? 102 GLU A OE1 1 
ATOM   623   O OE2 . GLU A 1 81  ? 172.673 231.478 174.234 1.00 111.49 ? 102 GLU A OE2 1 
ATOM   624   N N   . ASN A 1 82  ? 173.165 225.177 176.850 1.00 119.13 ? 103 ASN A N   1 
ATOM   625   C CA  . ASN A 1 82  ? 173.198 223.731 176.963 1.00 119.13 ? 103 ASN A CA  1 
ATOM   626   C C   . ASN A 1 82  ? 172.185 223.300 178.036 1.00 119.13 ? 103 ASN A C   1 
ATOM   627   O O   . ASN A 1 82  ? 171.461 224.125 178.601 1.00 119.13 ? 103 ASN A O   1 
ATOM   628   C CB  . ASN A 1 82  ? 174.644 223.296 177.246 1.00 119.13 ? 103 ASN A CB  1 
ATOM   629   C CG  . ASN A 1 82  ? 174.886 221.820 176.979 1.00 119.13 ? 103 ASN A CG  1 
ATOM   630   O OD1 . ASN A 1 82  ? 173.960 221.090 176.625 1.00 119.13 ? 103 ASN A OD1 1 
ATOM   631   N ND2 . ASN A 1 82  ? 176.122 221.374 177.155 1.00 119.13 ? 103 ASN A ND2 1 
ATOM   632   N N   . ILE A 1 83  ? 172.126 221.998 178.322 1.00 134.74 ? 104 ILE A N   1 
ATOM   633   C CA  . ILE A 1 83  ? 171.196 221.420 179.289 1.00 134.74 ? 104 ILE A CA  1 
ATOM   634   C C   . ILE A 1 83  ? 171.789 221.431 180.695 1.00 134.74 ? 104 ILE A C   1 
ATOM   635   O O   . ILE A 1 83  ? 171.236 220.806 181.609 1.00 134.74 ? 104 ILE A O   1 
ATOM   636   C CB  . ILE A 1 83  ? 170.800 219.991 178.874 1.00 134.74 ? 104 ILE A CB  1 
ATOM   637   C CG1 . ILE A 1 83  ? 172.035 219.088 178.821 1.00 134.74 ? 104 ILE A CG1 1 
ATOM   638   C CG2 . ILE A 1 83  ? 170.076 220.005 177.533 1.00 134.74 ? 104 ILE A CG2 1 
ATOM   639   C CD1 . ILE A 1 83  ? 171.717 217.621 178.631 1.00 134.74 ? 104 ILE A CD1 1 
ATOM   640   N N   . PHE A 1 84  ? 172.930 222.115 180.856 1.00 126.98 ? 105 PHE A N   1 
ATOM   641   C CA  . PHE A 1 84  ? 173.569 222.422 182.146 1.00 126.98 ? 105 PHE A CA  1 
ATOM   642   C C   . PHE A 1 84  ? 174.008 221.148 182.875 1.00 126.98 ? 105 PHE A C   1 
ATOM   643   O O   . PHE A 1 84  ? 173.647 220.899 184.028 1.00 126.98 ? 105 PHE A O   1 
ATOM   644   C CB  . PHE A 1 84  ? 172.675 223.288 183.061 1.00 126.98 ? 105 PHE A CB  1 
ATOM   645   C CG  . PHE A 1 84  ? 172.467 224.734 182.607 1.00 126.98 ? 105 PHE A CG  1 
ATOM   646   C CD1 . PHE A 1 84  ? 172.870 225.203 181.360 1.00 126.98 ? 105 PHE A CD1 1 
ATOM   647   C CD2 . PHE A 1 84  ? 171.851 225.632 183.473 1.00 126.98 ? 105 PHE A CD2 1 
ATOM   648   C CE1 . PHE A 1 84  ? 172.663 226.523 180.989 1.00 126.98 ? 105 PHE A CE1 1 
ATOM   649   C CE2 . PHE A 1 84  ? 171.641 226.953 183.108 1.00 126.98 ? 105 PHE A CE2 1 
ATOM   650   C CZ  . PHE A 1 84  ? 172.048 227.398 181.865 1.00 126.98 ? 105 PHE A CZ  1 
ATOM   651   N N   . GLY A 1 85  ? 174.814 220.345 182.187 1.00 100.80 ? 106 GLY A N   1 
ATOM   652   C CA  . GLY A 1 85  ? 175.310 219.120 182.786 1.00 100.80 ? 106 GLY A CA  1 
ATOM   653   C C   . GLY A 1 85  ? 176.016 218.252 181.764 1.00 100.80 ? 106 GLY A C   1 
ATOM   654   O O   . GLY A 1 85  ? 176.527 218.748 180.756 1.00 100.80 ? 106 GLY A O   1 
ATOM   655   N N   . ALA A 1 86  ? 176.032 216.945 182.061 1.00 79.23  ? 107 ALA A N   1 
ATOM   656   C CA  . ALA A 1 86  ? 176.665 215.884 181.276 1.00 79.23  ? 107 ALA A CA  1 
ATOM   657   C C   . ALA A 1 86  ? 178.146 216.158 181.025 1.00 79.23  ? 107 ALA A C   1 
ATOM   658   O O   . ALA A 1 86  ? 178.893 216.363 181.987 1.00 79.23  ? 107 ALA A O   1 
ATOM   659   C CB  . ALA A 1 86  ? 175.913 215.659 179.962 1.00 79.23  ? 107 ALA A CB  1 
ATOM   660   N N   . ILE A 1 87  ? 178.562 216.113 179.749 1.00 64.00  ? 108 ILE A N   1 
ATOM   661   C CA  . ILE A 1 87  ? 179.919 216.349 179.237 1.00 64.00  ? 108 ILE A CA  1 
ATOM   662   C C   . ILE A 1 87  ? 180.886 215.284 179.743 1.00 64.00  ? 108 ILE A C   1 
ATOM   663   O O   . ILE A 1 87  ? 181.297 215.298 180.908 1.00 64.00  ? 108 ILE A O   1 
ATOM   664   C CB  . ILE A 1 87  ? 180.454 217.760 179.571 1.00 64.00  ? 108 ILE A CB  1 
ATOM   665   C CG1 . ILE A 1 87  ? 179.469 218.853 179.155 1.00 64.00  ? 108 ILE A CG1 1 
ATOM   666   C CG2 . ILE A 1 87  ? 181.805 217.986 178.906 1.00 64.00  ? 108 ILE A CG2 1 
ATOM   667   C CD1 . ILE A 1 87  ? 179.245 218.937 177.678 1.00 64.00  ? 108 ILE A CD1 1 
ATOM   668   N N   . VAL A 1 88  ? 181.284 214.369 178.860 1.00 50.49  ? 109 VAL A N   1 
ATOM   669   C CA  . VAL A 1 88  ? 182.307 213.375 179.172 1.00 50.49  ? 109 VAL A CA  1 
ATOM   670   C C   . VAL A 1 88  ? 183.413 213.488 178.128 1.00 50.49  ? 109 VAL A C   1 
ATOM   671   O O   . VAL A 1 88  ? 183.137 213.708 176.943 1.00 50.49  ? 109 VAL A O   1 
ATOM   672   C CB  . VAL A 1 88  ? 181.743 211.939 179.248 1.00 50.49  ? 109 VAL A CB  1 
ATOM   673   C CG1 . VAL A 1 88  ? 180.818 211.805 180.445 1.00 50.49  ? 109 VAL A CG1 1 
ATOM   674   C CG2 . VAL A 1 88  ? 180.973 211.561 177.988 1.00 50.49  ? 109 VAL A CG2 1 
ATOM   675   N N   . ALA A 1 89  ? 184.663 213.401 178.573 1.00 37.42  ? 110 ALA A N   1 
ATOM   676   C CA  . ALA A 1 89  ? 185.798 213.600 177.683 1.00 37.42  ? 110 ALA A CA  1 
ATOM   677   C C   . ALA A 1 89  ? 186.116 212.311 176.939 1.00 37.42  ? 110 ALA A C   1 
ATOM   678   O O   . ALA A 1 89  ? 186.249 211.249 177.553 1.00 37.42  ? 110 ALA A O   1 
ATOM   679   C CB  . ALA A 1 89  ? 187.018 214.074 178.471 1.00 37.42  ? 110 ALA A CB  1 
ATOM   680   N N   . GLY A 1 90  ? 186.225 212.409 175.613 1.00 42.57  ? 111 GLY A N   1 
ATOM   681   C CA  . GLY A 1 90  ? 186.571 211.244 174.816 1.00 42.57  ? 111 GLY A CA  1 
ATOM   682   C C   . GLY A 1 90  ? 187.997 210.776 175.040 1.00 42.57  ? 111 GLY A C   1 
ATOM   683   O O   . GLY A 1 90  ? 188.278 209.576 175.008 1.00 42.57  ? 111 GLY A O   1 
ATOM   684   N N   . ALA A 1 91  ? 188.917 211.720 175.255 1.00 42.00  ? 112 ALA A N   1 
ATOM   685   C CA  . ALA A 1 91  ? 190.313 211.360 175.486 1.00 42.00  ? 112 ALA A CA  1 
ATOM   686   C C   . ALA A 1 91  ? 190.505 210.715 176.853 1.00 42.00  ? 112 ALA A C   1 
ATOM   687   O O   . ALA A 1 91  ? 191.337 209.814 177.011 1.00 42.00  ? 112 ALA A O   1 
ATOM   688   C CB  . ALA A 1 91  ? 191.203 212.595 175.347 1.00 42.00  ? 112 ALA A CB  1 
ATOM   689   N N   . ALA A 1 92  ? 189.744 211.161 177.853 1.00 38.90  ? 113 ALA A N   1 
ATOM   690   C CA  . ALA A 1 92  ? 189.889 210.612 179.195 1.00 38.90  ? 113 ALA A CA  1 
ATOM   691   C C   . ALA A 1 92  ? 189.153 209.291 179.372 1.00 38.90  ? 113 ALA A C   1 
ATOM   692   O O   . ALA A 1 92  ? 189.358 208.615 180.385 1.00 38.90  ? 113 ALA A O   1 
ATOM   693   C CB  . ALA A 1 92  ? 189.399 211.622 180.233 1.00 38.90  ? 113 ALA A CB  1 
ATOM   694   N N   . LEU A 1 93  ? 188.305 208.908 178.419 1.00 39.70  ? 114 LEU A N   1 
ATOM   695   C CA  . LEU A 1 93  ? 187.504 207.696 178.535 1.00 39.70  ? 114 LEU A CA  1 
ATOM   696   C C   . LEU A 1 93  ? 188.067 206.554 177.693 1.00 39.70  ? 114 LEU A C   1 
ATOM   697   O O   . LEU A 1 93  ? 187.761 205.386 177.961 1.00 39.70  ? 114 LEU A O   1 
ATOM   698   C CB  . LEU A 1 93  ? 186.052 208.004 178.148 1.00 39.70  ? 114 LEU A CB  1 
ATOM   699   C CG  . LEU A 1 93  ? 184.929 206.978 178.315 1.00 39.70  ? 114 LEU A CG  1 
ATOM   700   C CD1 . LEU A 1 93  ? 184.734 206.634 179.781 1.00 39.70  ? 114 LEU A CD1 1 
ATOM   701   C CD2 . LEU A 1 93  ? 183.636 207.494 177.706 1.00 39.70  ? 114 LEU A CD2 1 
ATOM   702   N N   . GLY A 1 94  ? 188.920 206.856 176.717 1.00 32.45  ? 115 GLY A N   1 
ATOM   703   C CA  . GLY A 1 94  ? 189.543 205.830 175.902 1.00 32.45  ? 115 GLY A CA  1 
ATOM   704   C C   . GLY A 1 94  ? 188.600 205.118 174.955 1.00 32.45  ? 115 GLY A C   1 
ATOM   705   O O   . GLY A 1 94  ? 188.177 205.688 173.947 1.00 32.45  ? 115 GLY A O   1 
ATOM   706   N N   . ILE A 1 95  ? 188.290 203.857 175.250 1.00 32.14  ? 116 ILE A N   1 
ATOM   707   C CA  . ILE A 1 95  ? 187.364 203.052 174.461 1.00 32.14  ? 116 ILE A CA  1 
ATOM   708   C C   . ILE A 1 95  ? 186.216 202.633 175.367 1.00 32.14  ? 116 ILE A C   1 
ATOM   709   O O   . ILE A 1 95  ? 186.445 202.066 176.442 1.00 32.14  ? 116 ILE A O   1 
ATOM   710   C CB  . ILE A 1 95  ? 188.058 201.822 173.846 1.00 32.14  ? 116 ILE A CB  1 
ATOM   711   C CG1 . ILE A 1 95  ? 189.289 202.246 173.042 1.00 32.14  ? 116 ILE A CG1 1 
ATOM   712   C CG2 . ILE A 1 95  ? 187.092 201.048 172.965 1.00 32.14  ? 116 ILE A CG2 1 
ATOM   713   C CD1 . ILE A 1 95  ? 190.234 201.115 172.722 1.00 32.14  ? 116 ILE A CD1 1 
ATOM   714   N N   . ALA A 1 96  ? 184.986 202.907 174.936 1.00 36.52  ? 117 ALA A N   1 
ATOM   715   C CA  . ALA A 1 96  ? 183.826 202.666 175.781 1.00 36.52  ? 117 ALA A CA  1 
ATOM   716   C C   . ALA A 1 96  ? 182.597 202.408 174.923 1.00 36.52  ? 117 ALA A C   1 
ATOM   717   O O   . ALA A 1 96  ? 182.574 202.705 173.726 1.00 36.52  ? 117 ALA A O   1 
ATOM   718   C CB  . ALA A 1 96  ? 183.568 203.846 176.722 1.00 36.52  ? 117 ALA A CB  1 
ATOM   719   N N   . THR A 1 97  ? 181.573 201.848 175.559 1.00 45.82  ? 118 THR A N   1 
ATOM   720   C CA  . THR A 1 97  ? 180.275 201.593 174.953 1.00 45.82  ? 118 THR A CA  1 
ATOM   721   C C   . THR A 1 97  ? 179.258 202.605 175.476 1.00 45.82  ? 118 THR A C   1 
ATOM   722   O O   . THR A 1 97  ? 179.594 203.543 176.203 1.00 45.82  ? 118 THR A O   1 
ATOM   723   C CB  . THR A 1 97  ? 179.819 200.160 175.232 1.00 45.82  ? 118 THR A CB  1 
ATOM   724   O OG1 . THR A 1 97  ? 179.401 200.047 176.598 1.00 45.82  ? 118 THR A OG1 1 
ATOM   725   C CG2 . THR A 1 97  ? 180.952 199.182 174.974 1.00 45.82  ? 118 THR A CG2 1 
ATOM   726   N N   . ALA A 1 98  ? 177.995 202.404 175.090 1.00 47.22  ? 119 ALA A N   1 
ATOM   727   C CA  . ALA A 1 98  ? 176.939 203.333 175.487 1.00 47.22  ? 119 ALA A CA  1 
ATOM   728   C C   . ALA A 1 98  ? 176.559 203.161 176.954 1.00 47.22  ? 119 ALA A C   1 
ATOM   729   O O   . ALA A 1 98  ? 176.286 204.148 177.652 1.00 47.22  ? 119 ALA A O   1 
ATOM   730   C CB  . ALA A 1 98  ? 175.716 203.143 174.593 1.00 47.22  ? 119 ALA A CB  1 
ATOM   731   N N   . ALA A 1 99  ? 176.528 201.912 177.432 1.00 46.61  ? 120 ALA A N   1 
ATOM   732   C CA  . ALA A 1 99  ? 176.128 201.638 178.809 1.00 46.61  ? 120 ALA A CA  1 
ATOM   733   C C   . ALA A 1 99  ? 177.145 202.163 179.813 1.00 46.61  ? 120 ALA A C   1 
ATOM   734   O O   . ALA A 1 99  ? 176.771 202.549 180.925 1.00 46.61  ? 120 ALA A O   1 
ATOM   735   C CB  . ALA A 1 99  ? 175.915 200.137 179.004 1.00 46.61  ? 120 ALA A CB  1 
ATOM   736   N N   . GLN A 1 100 ? 178.424 202.210 179.433 1.00 46.67  ? 121 GLN A N   1 
ATOM   737   C CA  . GLN A 1 100 ? 179.440 202.766 180.320 1.00 46.67  ? 121 GLN A CA  1 
ATOM   738   C C   . GLN A 1 100 ? 179.282 204.277 180.460 1.00 46.67  ? 121 GLN A C   1 
ATOM   739   O O   . GLN A 1 100 ? 179.444 204.826 181.559 1.00 46.67  ? 121 GLN A O   1 
ATOM   740   C CB  . GLN A 1 100 ? 180.830 202.398 179.803 1.00 46.67  ? 121 GLN A CB  1 
ATOM   741   C CG  . GLN A 1 100 ? 181.001 200.897 179.587 1.00 46.67  ? 121 GLN A CG  1 
ATOM   742   C CD  . GLN A 1 100 ? 182.387 200.515 179.110 1.00 46.67  ? 121 GLN A CD  1 
ATOM   743   O OE1 . GLN A 1 100 ? 183.250 201.370 178.924 1.00 46.67  ? 121 GLN A OE1 1 
ATOM   744   N NE2 . GLN A 1 100 ? 182.605 199.221 178.907 1.00 46.67  ? 121 GLN A NE2 1 
ATOM   745   N N   . VAL A 1 101 ? 178.935 204.956 179.362 1.00 43.10  ? 122 VAL A N   1 
ATOM   746   C CA  . VAL A 1 101 ? 178.637 206.386 179.406 1.00 43.10  ? 122 VAL A CA  1 
ATOM   747   C C   . VAL A 1 101 ? 177.390 206.645 180.247 1.00 43.10  ? 122 VAL A C   1 
ATOM   748   O O   . VAL A 1 101 ? 177.345 207.597 181.040 1.00 43.10  ? 122 VAL A O   1 
ATOM   749   C CB  . VAL A 1 101 ? 178.492 206.931 177.970 1.00 43.10  ? 122 VAL A CB  1 
ATOM   750   C CG1 . VAL A 1 101 ? 178.094 208.401 177.967 1.00 43.10  ? 122 VAL A CG1 1 
ATOM   751   C CG2 . VAL A 1 101 ? 179.786 206.733 177.198 1.00 43.10  ? 122 VAL A CG2 1 
ATOM   752   N N   . THR A 1 102 ? 176.377 205.777 180.116 1.00 39.77  ? 123 THR A N   1 
ATOM   753   C CA  . THR A 1 102 ? 175.167 205.898 180.928 1.00 39.77  ? 123 THR A CA  1 
ATOM   754   C C   . THR A 1 102 ? 175.461 205.677 182.411 1.00 39.77  ? 123 THR A C   1 
ATOM   755   O O   . THR A 1 102 ? 174.880 206.346 183.273 1.00 39.77  ? 123 THR A O   1 
ATOM   756   C CB  . THR A 1 102 ? 174.110 204.907 180.440 1.00 39.77  ? 123 THR A CB  1 
ATOM   757   O OG1 . THR A 1 102 ? 174.093 204.893 179.008 1.00 39.77  ? 123 THR A OG1 1 
ATOM   758   C CG2 . THR A 1 102 ? 172.732 205.302 180.949 1.00 39.77  ? 123 THR A CG2 1 
ATOM   759   N N   . SER A 1 103 ? 176.387 204.766 182.723 1.00 37.15  ? 124 SER A N   1 
ATOM   760   C CA  . SER A 1 103 ? 176.791 204.556 184.111 1.00 37.15  ? 124 SER A CA  1 
ATOM   761   C C   . SER A 1 103 ? 177.556 205.757 184.662 1.00 37.15  ? 124 SER A C   1 
ATOM   762   O O   . SER A 1 103 ? 177.399 206.107 185.837 1.00 37.15  ? 124 SER A O   1 
ATOM   763   C CB  . SER A 1 103 ? 177.631 203.286 184.225 1.00 37.15  ? 124 SER A CB  1 
ATOM   764   O OG  . SER A 1 103 ? 176.878 202.145 183.855 1.00 37.15  ? 124 SER A OG  1 
ATOM   765   N N   . VAL A 1 104 ? 178.386 206.396 183.828 1.00 35.74  ? 125 VAL A N   1 
ATOM   766   C CA  . VAL A 1 104 ? 179.089 207.615 184.239 1.00 35.74  ? 125 VAL A CA  1 
ATOM   767   C C   . VAL A 1 104 ? 178.094 208.736 184.541 1.00 35.74  ? 125 VAL A C   1 
ATOM   768   O O   . VAL A 1 104 ? 178.223 209.455 185.548 1.00 35.74  ? 125 VAL A O   1 
ATOM   769   C CB  . VAL A 1 104 ? 180.116 208.017 183.161 1.00 35.74  ? 125 VAL A CB  1 
ATOM   770   C CG1 . VAL A 1 104 ? 180.644 209.422 183.386 1.00 35.74  ? 125 VAL A CG1 1 
ATOM   771   C CG2 . VAL A 1 104 ? 181.277 207.039 183.159 1.00 35.74  ? 125 VAL A CG2 1 
ATOM   772   N N   . VAL A 1 105 ? 177.061 208.866 183.701 1.00 34.62  ? 126 VAL A N   1 
ATOM   773   C CA  . VAL A 1 105 ? 175.980 209.821 183.953 1.00 34.62  ? 126 VAL A CA  1 
ATOM   774   C C   . VAL A 1 105 ? 175.223 209.463 185.235 1.00 34.62  ? 126 VAL A C   1 
ATOM   775   O O   . VAL A 1 105 ? 174.823 210.350 186.001 1.00 34.62  ? 126 VAL A O   1 
ATOM   776   C CB  . VAL A 1 105 ? 175.055 209.895 182.720 1.00 34.62  ? 126 VAL A CB  1 
ATOM   777   C CG1 . VAL A 1 105 ? 173.825 210.759 182.971 1.00 34.62  ? 126 VAL A CG1 1 
ATOM   778   C CG2 . VAL A 1 105 ? 175.816 210.456 181.534 1.00 34.62  ? 126 VAL A CG2 1 
ATOM   779   N N   . ALA A 1 106 ? 175.064 208.163 185.516 1.00 31.99  ? 127 ALA A N   1 
ATOM   780   C CA  . ALA A 1 106 ? 174.394 207.724 186.742 1.00 31.99  ? 127 ALA A CA  1 
ATOM   781   C C   . ALA A 1 106 ? 175.180 208.101 187.997 1.00 31.99  ? 127 ALA A C   1 
ATOM   782   O O   . ALA A 1 106 ? 174.591 208.558 188.986 1.00 31.99  ? 127 ALA A O   1 
ATOM   783   C CB  . ALA A 1 106 ? 174.154 206.216 186.696 1.00 31.99  ? 127 ALA A CB  1 
ATOM   784   N N   . LEU A 1 107 ? 176.506 207.914 187.979 1.00 29.20  ? 128 LEU A N   1 
ATOM   785   C CA  . LEU A 1 107 ? 177.334 208.358 189.105 1.00 29.20  ? 128 LEU A CA  1 
ATOM   786   C C   . LEU A 1 107 ? 177.323 209.875 189.267 1.00 29.20  ? 128 LEU A C   1 
ATOM   787   O O   . LEU A 1 107 ? 177.275 210.381 190.399 1.00 29.20  ? 128 LEU A O   1 
ATOM   788   C CB  . LEU A 1 107 ? 178.773 207.853 188.974 1.00 29.20  ? 128 LEU A CB  1 
ATOM   789   C CG  . LEU A 1 107 ? 179.183 206.466 189.487 1.00 29.20  ? 128 LEU A CG  1 
ATOM   790   C CD1 . LEU A 1 107 ? 178.693 205.293 188.675 1.00 29.20  ? 128 LEU A CD1 1 
ATOM   791   C CD2 . LEU A 1 107 ? 180.695 206.434 189.575 1.00 29.20  ? 128 LEU A CD2 1 
ATOM   792   N N   . HIS A 1 108 ? 177.362 210.620 188.155 1.00 38.36  ? 129 HIS A N   1 
ATOM   793   C CA  . HIS A 1 108 ? 177.300 212.078 188.258 1.00 38.36  ? 129 HIS A CA  1 
ATOM   794   C C   . HIS A 1 108 ? 175.935 212.558 188.744 1.00 38.36  ? 129 HIS A C   1 
ATOM   795   O O   . HIS A 1 108 ? 175.837 213.626 189.358 1.00 38.36  ? 129 HIS A O   1 
ATOM   796   C CB  . HIS A 1 108 ? 177.643 212.724 186.917 1.00 38.36  ? 129 HIS A CB  1 
ATOM   797   C CG  . HIS A 1 108 ? 177.787 214.213 186.989 1.00 38.36  ? 129 HIS A CG  1 
ATOM   798   N ND1 . HIS A 1 108 ? 178.893 214.828 187.533 1.00 38.36  ? 129 HIS A ND1 1 
ATOM   799   C CD2 . HIS A 1 108 ? 176.961 215.209 186.591 1.00 38.36  ? 129 HIS A CD2 1 
ATOM   800   C CE1 . HIS A 1 108 ? 178.745 216.139 187.464 1.00 38.36  ? 129 HIS A CE1 1 
ATOM   801   N NE2 . HIS A 1 108 ? 177.581 216.396 186.896 1.00 38.36  ? 129 HIS A NE2 1 
ATOM   802   N N   . LYS A 1 109 ? 174.881 211.783 188.491 1.00 39.21  ? 130 LYS A N   1 
ATOM   803   C CA  . LYS A 1 109 ? 173.565 212.115 189.023 1.00 39.21  ? 130 LYS A CA  1 
ATOM   804   C C   . LYS A 1 109 ? 173.449 211.767 190.504 1.00 39.21  ? 130 LYS A C   1 
ATOM   805   O O   . LYS A 1 109 ? 172.789 212.487 191.261 1.00 39.21  ? 130 LYS A O   1 
ATOM   806   C CB  . LYS A 1 109 ? 172.484 211.392 188.219 1.00 39.21  ? 130 LYS A CB  1 
ATOM   807   C CG  . LYS A 1 109 ? 171.082 211.943 188.415 1.00 39.21  ? 130 LYS A CG  1 
ATOM   808   C CD  . LYS A 1 109 ? 170.958 213.347 187.845 1.00 39.21  ? 130 LYS A CD  1 
ATOM   809   C CE  . LYS A 1 109 ? 171.194 213.360 186.342 1.00 39.21  ? 130 LYS A CE  1 
ATOM   810   N NZ  . LYS A 1 109 ? 170.137 212.615 185.605 1.00 39.21  ? 130 LYS A NZ  1 
ATOM   811   N N   . SER A 1 110 ? 174.078 210.674 190.936 1.00 31.43  ? 131 SER A N   1 
ATOM   812   C CA  . SER A 1 110 ? 173.926 210.179 192.299 1.00 31.43  ? 131 SER A CA  1 
ATOM   813   C C   . SER A 1 110 ? 175.024 210.644 193.250 1.00 31.43  ? 131 SER A C   1 
ATOM   814   O O   . SER A 1 110 ? 175.056 210.180 194.397 1.00 31.43  ? 131 SER A O   1 
ATOM   815   C CB  . SER A 1 110 ? 173.871 208.650 192.296 1.00 31.43  ? 131 SER A CB  1 
ATOM   816   O OG  . SER A 1 110 ? 173.666 208.147 193.603 1.00 31.43  ? 131 SER A OG  1 
ATOM   817   N N   . ASN A 1 111 ? 175.929 211.521 192.789 1.00 28.96  ? 132 ASN A N   1 
ATOM   818   C CA  . ASN A 1 111 ? 177.005 212.042 193.639 1.00 28.96  ? 132 ASN A CA  1 
ATOM   819   C C   . ASN A 1 111 ? 176.481 212.783 194.870 1.00 28.96  ? 132 ASN A C   1 
ATOM   820   O O   . ASN A 1 111 ? 177.035 212.636 195.968 1.00 28.96  ? 132 ASN A O   1 
ATOM   821   C CB  . ASN A 1 111 ? 177.904 212.968 192.819 1.00 28.96  ? 132 ASN A CB  1 
ATOM   822   C CG  . ASN A 1 111 ? 179.332 213.012 193.333 1.00 28.96  ? 132 ASN A CG  1 
ATOM   823   O OD1 . ASN A 1 111 ? 179.578 212.972 194.538 1.00 28.96  ? 132 ASN A OD1 1 
ATOM   824   N ND2 . ASN A 1 111 ? 180.284 213.103 192.413 1.00 28.96  ? 132 ASN A ND2 1 
ATOM   825   N N   . GLN A 1 112 ? 175.422 213.587 194.707 1.00 35.10  ? 133 GLN A N   1 
ATOM   826   C CA  . GLN A 1 112 ? 174.898 214.375 195.824 1.00 35.10  ? 133 GLN A CA  1 
ATOM   827   C C   . GLN A 1 112 ? 174.280 213.490 196.901 1.00 35.10  ? 133 GLN A C   1 
ATOM   828   O O   . GLN A 1 112 ? 174.516 213.701 198.099 1.00 35.10  ? 133 GLN A O   1 
ATOM   829   C CB  . GLN A 1 112 ? 173.872 215.389 195.319 1.00 35.10  ? 133 GLN A CB  1 
ATOM   830   C CG  . GLN A 1 112 ? 174.428 216.412 194.343 1.00 35.10  ? 133 GLN A CG  1 
ATOM   831   C CD  . GLN A 1 112 ? 174.209 216.018 192.895 1.00 35.10  ? 133 GLN A CD  1 
ATOM   832   O OE1 . GLN A 1 112 ? 174.094 214.836 192.572 1.00 35.10  ? 133 GLN A OE1 1 
ATOM   833   N NE2 . GLN A 1 112 ? 174.149 217.011 192.015 1.00 35.10  ? 133 GLN A NE2 1 
ATOM   834   N N   . ASN A 1 113 ? 173.509 212.478 196.497 1.00 32.83  ? 134 ASN A N   1 
ATOM   835   C CA  . ASN A 1 113 ? 172.940 211.558 197.475 1.00 32.83  ? 134 ASN A CA  1 
ATOM   836   C C   . ASN A 1 113 ? 174.008 210.662 198.087 1.00 32.83  ? 134 ASN A C   1 
ATOM   837   O O   . ASN A 1 113 ? 173.883 210.270 199.254 1.00 32.83  ? 134 ASN A O   1 
ATOM   838   C CB  . ASN A 1 113 ? 171.836 210.719 196.836 1.00 32.83  ? 134 ASN A CB  1 
ATOM   839   C CG  . ASN A 1 113 ? 170.891 210.129 197.862 1.00 32.83  ? 134 ASN A CG  1 
ATOM   840   O OD1 . ASN A 1 113 ? 170.551 210.775 198.853 1.00 32.83  ? 134 ASN A OD1 1 
ATOM   841   N ND2 . ASN A 1 113 ? 170.457 208.897 197.629 1.00 32.83  ? 134 ASN A ND2 1 
ATOM   842   N N   . ALA A 1 114 ? 175.068 210.348 197.330 1.00 29.08  ? 135 ALA A N   1 
ATOM   843   C CA  . ALA A 1 114 ? 176.194 209.609 197.895 1.00 29.08  ? 135 ALA A CA  1 
ATOM   844   C C   . ALA A 1 114 ? 176.901 210.416 198.976 1.00 29.08  ? 135 ALA A C   1 
ATOM   845   O O   . ALA A 1 114 ? 177.283 209.869 200.016 1.00 29.08  ? 135 ALA A O   1 
ATOM   846   C CB  . ALA A 1 114 ? 177.174 209.220 196.789 1.00 29.08  ? 135 ALA A CB  1 
ATOM   847   N N   . ALA A 1 115 ? 177.063 211.725 198.758 1.00 35.00  ? 136 ALA A N   1 
ATOM   848   C CA  . ALA A 1 115 ? 177.639 212.588 199.788 1.00 35.00  ? 136 ALA A CA  1 
ATOM   849   C C   . ALA A 1 115 ? 176.708 212.727 200.991 1.00 35.00  ? 136 ALA A C   1 
ATOM   850   O O   . ALA A 1 115 ? 177.172 212.799 202.138 1.00 35.00  ? 136 ALA A O   1 
ATOM   851   C CB  . ALA A 1 115 ? 177.965 213.961 199.202 1.00 35.00  ? 136 ALA A CB  1 
ATOM   852   N N   . LYS A 1 116 ? 175.392 212.758 200.745 1.00 36.39  ? 137 LYS A N   1 
ATOM   853   C CA  . LYS A 1 116 ? 174.423 212.836 201.838 1.00 36.39  ? 137 LYS A CA  1 
ATOM   854   C C   . LYS A 1 116 ? 174.451 211.585 202.711 1.00 36.39  ? 137 LYS A C   1 
ATOM   855   O O   . LYS A 1 116 ? 174.323 211.675 203.938 1.00 36.39  ? 137 LYS A O   1 
ATOM   856   C CB  . LYS A 1 116 ? 173.018 213.062 201.281 1.00 36.39  ? 137 LYS A CB  1 
ATOM   857   C CG  . LYS A 1 116 ? 172.732 214.499 200.879 1.00 36.39  ? 137 LYS A CG  1 
ATOM   858   C CD  . LYS A 1 116 ? 171.238 214.747 200.744 1.00 36.39  ? 137 LYS A CD  1 
ATOM   859   C CE  . LYS A 1 116 ? 170.517 214.570 202.073 1.00 36.39  ? 137 LYS A CE  1 
ATOM   860   N NZ  . LYS A 1 116 ? 171.231 215.230 203.201 1.00 36.39  ? 137 LYS A NZ  1 
ATOM   861   N N   . ILE A 1 117 ? 174.606 210.408 202.098 1.00 33.11  ? 138 ILE A N   1 
ATOM   862   C CA  . ILE A 1 117 ? 174.763 209.184 202.882 1.00 33.11  ? 138 ILE A CA  1 
ATOM   863   C C   . ILE A 1 117 ? 176.125 209.157 203.576 1.00 33.11  ? 138 ILE A C   1 
ATOM   864   O O   . ILE A 1 117 ? 176.232 208.758 204.743 1.00 33.11  ? 138 ILE A O   1 
ATOM   865   C CB  . ILE A 1 117 ? 174.537 207.945 201.994 1.00 33.11  ? 138 ILE A CB  1 
ATOM   866   C CG1 . ILE A 1 117 ? 173.125 207.957 201.411 1.00 33.11  ? 138 ILE A CG1 1 
ATOM   867   C CG2 . ILE A 1 117 ? 174.713 206.666 202.779 1.00 33.11  ? 138 ILE A CG2 1 
ATOM   868   C CD1 . ILE A 1 117 ? 172.945 207.020 200.239 1.00 33.11  ? 138 ILE A CD1 1 
ATOM   869   N N   . ASN A 1 118 ? 177.178 209.620 202.889 1.00 31.70  ? 139 ASN A N   1 
ATOM   870   C CA  . ASN A 1 118 ? 178.527 209.626 203.449 1.00 31.70  ? 139 ASN A CA  1 
ATOM   871   C C   . ASN A 1 118 ? 178.693 210.604 204.606 1.00 31.70  ? 139 ASN A C   1 
ATOM   872   O O   . ASN A 1 118 ? 179.659 210.482 205.367 1.00 31.70  ? 139 ASN A O   1 
ATOM   873   C CB  . ASN A 1 118 ? 179.543 209.962 202.358 1.00 31.70  ? 139 ASN A CB  1 
ATOM   874   C CG  . ASN A 1 118 ? 179.950 208.752 201.548 1.00 31.70  ? 139 ASN A CG  1 
ATOM   875   O OD1 . ASN A 1 118 ? 180.295 207.708 202.101 1.00 31.70  ? 139 ASN A OD1 1 
ATOM   876   N ND2 . ASN A 1 118 ? 179.910 208.885 200.229 1.00 31.70  ? 139 ASN A ND2 1 
ATOM   877   N N   . SER A 1 119 ? 177.784 211.572 204.751 1.00 33.46  ? 140 SER A N   1 
ATOM   878   C CA  . SER A 1 119 ? 177.816 212.483 205.893 1.00 33.46  ? 140 SER A CA  1 
ATOM   879   C C   . SER A 1 119 ? 177.502 211.811 207.230 1.00 33.46  ? 140 SER A C   1 
ATOM   880   O O   . SER A 1 119 ? 177.736 212.427 208.274 1.00 33.46  ? 140 SER A O   1 
ATOM   881   C CB  . SER A 1 119 ? 176.839 213.636 205.664 1.00 33.46  ? 140 SER A CB  1 
ATOM   882   O OG  . SER A 1 119 ? 177.231 214.422 204.552 1.00 33.46  ? 140 SER A OG  1 
ATOM   883   N N   . LEU A 1 120 ? 176.985 210.580 207.232 1.00 38.31  ? 141 LEU A N   1 
ATOM   884   C CA  . LEU A 1 120 ? 176.668 209.874 208.470 1.00 38.31  ? 141 LEU A CA  1 
ATOM   885   C C   . LEU A 1 120 ? 177.545 208.640 208.645 1.00 38.31  ? 141 LEU A C   1 
ATOM   886   O O   . LEU A 1 120 ? 177.043 207.559 208.973 1.00 38.31  ? 141 LEU A O   1 
ATOM   887   C CB  . LEU A 1 120 ? 175.191 209.474 208.500 1.00 38.31  ? 141 LEU A CB  1 
ATOM   888   C CG  . LEU A 1 120 ? 174.177 210.615 208.547 1.00 38.31  ? 141 LEU A CG  1 
ATOM   889   C CD1 . LEU A 1 120 ? 172.763 210.079 208.397 1.00 38.31  ? 141 LEU A CD1 1 
ATOM   890   C CD2 . LEU A 1 120 ? 174.324 211.395 209.842 1.00 38.31  ? 141 LEU A CD2 1 
ATOM   891   N N   . ARG A 1 121 ? 178.853 208.799 208.405 1.00 33.86  ? 142 ARG A N   1 
ATOM   892   C CA  . ARG A 1 121 ? 179.796 207.687 208.514 1.00 33.86  ? 142 ARG A CA  1 
ATOM   893   C C   . ARG A 1 121 ? 179.895 207.175 209.948 1.00 33.86  ? 142 ARG A C   1 
ATOM   894   O O   . ARG A 1 121 ? 179.961 205.960 210.176 1.00 33.86  ? 142 ARG A O   1 
ATOM   895   C CB  . ARG A 1 121 ? 181.166 208.123 207.989 1.00 33.86  ? 142 ARG A CB  1 
ATOM   896   C CG  . ARG A 1 121 ? 182.322 207.191 208.326 1.00 33.86  ? 142 ARG A CG  1 
ATOM   897   C CD  . ARG A 1 121 ? 183.449 207.285 207.310 1.00 33.86  ? 142 ARG A CD  1 
ATOM   898   N NE  . ARG A 1 121 ? 183.963 208.642 207.169 1.00 33.86  ? 142 ARG A NE  1 
ATOM   899   C CZ  . ARG A 1 121 ? 183.853 209.374 206.069 1.00 33.86  ? 142 ARG A CZ  1 
ATOM   900   N NH1 . ARG A 1 121 ? 183.250 208.909 204.988 1.00 33.86  ? 142 ARG A NH1 1 
ATOM   901   N NH2 . ARG A 1 121 ? 184.359 210.603 206.055 1.00 33.86  ? 142 ARG A NH2 1 
ATOM   902   N N   . ASP A 1 122 ? 179.872 208.083 210.928 1.00 41.70  ? 143 ASP A N   1 
ATOM   903   C CA  . ASP A 1 122 ? 179.879 207.666 212.327 1.00 41.70  ? 143 ASP A CA  1 
ATOM   904   C C   . ASP A 1 122 ? 178.575 206.984 212.723 1.00 41.70  ? 143 ASP A C   1 
ATOM   905   O O   . ASP A 1 122 ? 178.566 206.156 213.641 1.00 41.70  ? 143 ASP A O   1 
ATOM   906   C CB  . ASP A 1 122 ? 180.145 208.867 213.234 1.00 41.70  ? 143 ASP A CB  1 
ATOM   907   C CG  . ASP A 1 122 ? 180.904 208.489 214.490 1.00 41.70  ? 143 ASP A CG  1 
ATOM   908   O OD1 . ASP A 1 122 ? 181.804 207.627 214.406 1.00 41.70  ? 143 ASP A OD1 1 
ATOM   909   O OD2 . ASP A 1 122 ? 180.599 209.052 215.562 1.00 41.70  ? 143 ASP A OD2 1 
ATOM   910   N N   . SER A 1 123 ? 177.470 207.312 212.049 1.00 38.32  ? 144 SER A N   1 
ATOM   911   C CA  . SER A 1 123 ? 176.224 206.594 212.291 1.00 38.32  ? 144 SER A CA  1 
ATOM   912   C C   . SER A 1 123 ? 176.234 205.218 211.638 1.00 38.32  ? 144 SER A C   1 
ATOM   913   O O   . SER A 1 123 ? 175.599 204.288 212.148 1.00 38.32  ? 144 SER A O   1 
ATOM   914   C CB  . SER A 1 123 ? 175.036 207.413 211.787 1.00 38.32  ? 144 SER A CB  1 
ATOM   915   O OG  . SER A 1 123 ? 174.882 208.604 212.538 1.00 38.32  ? 144 SER A OG  1 
ATOM   916   N N   . ILE A 1 124 ? 176.935 205.076 210.510 1.00 32.64  ? 145 ILE A N   1 
ATOM   917   C CA  . ILE A 1 124 ? 177.012 203.788 209.824 1.00 32.64  ? 145 ILE A CA  1 
ATOM   918   C C   . ILE A 1 124 ? 177.863 202.798 210.618 1.00 32.64  ? 145 ILE A C   1 
ATOM   919   O O   . ILE A 1 124 ? 177.502 201.623 210.763 1.00 32.64  ? 145 ILE A O   1 
ATOM   920   C CB  . ILE A 1 124 ? 177.538 203.997 208.389 1.00 32.64  ? 145 ILE A CB  1 
ATOM   921   C CG1 . ILE A 1 124 ? 176.457 204.631 207.515 1.00 32.64  ? 145 ILE A CG1 1 
ATOM   922   C CG2 . ILE A 1 124 ? 178.011 202.695 207.751 1.00 32.64  ? 145 ILE A CG2 1 
ATOM   923   C CD1 . ILE A 1 124 ? 176.947 205.028 206.145 1.00 32.64  ? 145 ILE A CD1 1 
ATOM   924   N N   . THR A 1 125 ? 178.978 203.259 211.181 1.00 35.75  ? 146 THR A N   1 
ATOM   925   C CA  . THR A 1 125 ? 179.923 202.365 211.845 1.00 35.75  ? 146 THR A CA  1 
ATOM   926   C C   . THR A 1 125 ? 179.518 201.986 213.266 1.00 35.75  ? 146 THR A C   1 
ATOM   927   O O   . THR A 1 125 ? 180.218 201.183 213.889 1.00 35.75  ? 146 THR A O   1 
ATOM   928   C CB  . THR A 1 125 ? 181.320 202.995 211.871 1.00 35.75  ? 146 THR A CB  1 
ATOM   929   O OG1 . THR A 1 125 ? 182.279 202.017 212.295 1.00 35.75  ? 146 THR A OG1 1 
ATOM   930   C CG2 . THR A 1 125 ? 181.360 204.177 212.825 1.00 35.75  ? 146 THR A CG2 1 
ATOM   931   N N   . LYS A 1 126 ? 178.427 202.533 213.800 1.00 38.63  ? 147 LYS A N   1 
ATOM   932   C CA  . LYS A 1 126 ? 178.053 202.280 215.187 1.00 38.63  ? 147 LYS A CA  1 
ATOM   933   C C   . LYS A 1 126 ? 176.942 201.248 215.343 1.00 38.63  ? 147 LYS A C   1 
ATOM   934   O O   . LYS A 1 126 ? 176.503 201.006 216.475 1.00 38.63  ? 147 LYS A O   1 
ATOM   935   C CB  . LYS A 1 126 ? 177.649 203.593 215.874 1.00 38.63  ? 147 LYS A CB  1 
ATOM   936   C CG  . LYS A 1 126 ? 176.253 204.104 215.542 1.00 38.63  ? 147 LYS A CG  1 
ATOM   937   C CD  . LYS A 1 126 ? 176.119 205.573 215.891 1.00 38.63  ? 147 LYS A CD  1 
ATOM   938   C CE  . LYS A 1 126 ? 174.661 205.995 215.948 1.00 38.63  ? 147 LYS A CE  1 
ATOM   939   N NZ  . LYS A 1 126 ? 173.930 205.666 214.697 1.00 38.63  ? 147 LYS A NZ  1 
ATOM   940   N N   . THR A 1 127 ? 176.491 200.625 214.253 1.00 39.21  ? 148 THR A N   1 
ATOM   941   C CA  . THR A 1 127 ? 175.409 199.651 214.339 1.00 39.21  ? 148 THR A CA  1 
ATOM   942   C C   . THR A 1 127 ? 175.873 198.369 215.022 1.00 39.21  ? 148 THR A C   1 
ATOM   943   O O   . THR A 1 127 ? 177.060 198.028 215.022 1.00 39.21  ? 148 THR A O   1 
ATOM   944   C CB  . THR A 1 127 ? 174.873 199.309 212.941 1.00 39.21  ? 148 THR A CB  1 
ATOM   945   O OG1 . THR A 1 127 ? 175.779 198.423 212.274 1.00 39.21  ? 148 THR A OG1 1 
ATOM   946   C CG2 . THR A 1 127 ? 174.680 200.566 212.118 1.00 39.21  ? 148 THR A CG2 1 
ATOM   947   N N   . ASN A 1 128 ? 174.917 197.670 215.635 1.00 37.88  ? 149 ASN A N   1 
ATOM   948   C CA  . ASN A 1 128 ? 175.214 196.429 216.337 1.00 37.88  ? 149 ASN A CA  1 
ATOM   949   C C   . ASN A 1 128 ? 174.160 195.355 216.106 1.00 37.88  ? 149 ASN A C   1 
ATOM   950   O O   . ASN A 1 128 ? 174.178 194.336 216.807 1.00 37.88  ? 149 ASN A O   1 
ATOM   951   C CB  . ASN A 1 128 ? 175.363 196.687 217.837 1.00 37.88  ? 149 ASN A CB  1 
ATOM   952   C CG  . ASN A 1 128 ? 174.202 197.469 218.406 1.00 37.88  ? 149 ASN A CG  1 
ATOM   953   O OD1 . ASN A 1 128 ? 174.054 198.660 218.138 1.00 37.88  ? 149 ASN A OD1 1 
ATOM   954   N ND2 . ASN A 1 128 ? 173.367 196.803 219.194 1.00 37.88  ? 149 ASN A ND2 1 
ATOM   955   N N   . GLN A 1 129 ? 173.246 195.544 215.161 1.00 38.91  ? 150 GLN A N   1 
ATOM   956   C CA  . GLN A 1 129 ? 172.243 194.548 214.823 1.00 38.91  ? 150 GLN A CA  1 
ATOM   957   C C   . GLN A 1 129 ? 172.377 194.163 213.357 1.00 38.91  ? 150 GLN A C   1 
ATOM   958   O O   . GLN A 1 129 ? 173.169 194.743 212.609 1.00 38.91  ? 150 GLN A O   1 
ATOM   959   C CB  . GLN A 1 129 ? 170.829 195.059 215.115 1.00 38.91  ? 150 GLN A CB  1 
ATOM   960   C CG  . GLN A 1 129 ? 170.502 195.137 216.592 1.00 38.91  ? 150 GLN A CG  1 
ATOM   961   C CD  . GLN A 1 129 ? 169.078 195.578 216.850 1.00 38.91  ? 150 GLN A CD  1 
ATOM   962   O OE1 . GLN A 1 129 ? 168.332 195.882 215.919 1.00 38.91  ? 150 GLN A OE1 1 
ATOM   963   N NE2 . GLN A 1 129 ? 168.691 195.614 218.119 1.00 38.91  ? 150 GLN A NE2 1 
ATOM   964   N N   . ALA A 1 130 ? 171.596 193.155 212.963 1.00 31.27  ? 151 ALA A N   1 
ATOM   965   C CA  . ALA A 1 130 ? 171.626 192.621 211.605 1.00 31.27  ? 151 ALA A CA  1 
ATOM   966   C C   . ALA A 1 130 ? 171.163 193.650 210.581 1.00 31.27  ? 151 ALA A C   1 
ATOM   967   O O   . ALA A 1 130 ? 171.959 194.096 209.751 1.00 31.27  ? 151 ALA A O   1 
ATOM   968   C CB  . ALA A 1 130 ? 170.769 191.358 211.513 1.00 31.27  ? 151 ALA A CB  1 
ATOM   969   N N   . VAL A 1 131 ? 169.889 194.043 210.632 1.00 26.45  ? 152 VAL A N   1 
ATOM   970   C CA  . VAL A 1 131 ? 169.338 195.083 209.766 1.00 26.45  ? 152 VAL A CA  1 
ATOM   971   C C   . VAL A 1 131 ? 168.620 196.104 210.641 1.00 26.45  ? 152 VAL A C   1 
ATOM   972   O O   . VAL A 1 131 ? 167.734 195.739 211.421 1.00 26.45  ? 152 VAL A O   1 
ATOM   973   C CB  . VAL A 1 131 ? 168.363 194.515 208.710 1.00 26.45  ? 152 VAL A CB  1 
ATOM   974   C CG1 . VAL A 1 131 ? 167.840 195.629 207.811 1.00 26.45  ? 152 VAL A CG1 1 
ATOM   975   C CG2 . VAL A 1 131 ? 169.008 193.414 207.866 1.00 26.45  ? 152 VAL A CG2 1 
ATOM   976   N N   . GLU A 1 132 ? 168.988 197.380 210.505 1.00 33.01  ? 153 GLU A N   1 
ATOM   977   C CA  . GLU A 1 132 ? 168.252 198.453 211.161 1.00 33.01  ? 153 GLU A CA  1 
ATOM   978   C C   . GLU A 1 132 ? 168.262 199.690 210.276 1.00 33.01  ? 153 GLU A C   1 
ATOM   979   O O   . GLU A 1 132 ? 168.862 199.710 209.199 1.00 33.01  ? 153 GLU A O   1 
ATOM   980   C CB  . GLU A 1 132 ? 168.812 198.792 212.545 1.00 33.01  ? 153 GLU A CB  1 
ATOM   981   C CG  . GLU A 1 132 ? 170.201 199.385 212.552 1.00 33.01  ? 153 GLU A CG  1 
ATOM   982   C CD  . GLU A 1 132 ? 170.692 199.630 213.963 1.00 33.01  ? 153 GLU A CD  1 
ATOM   983   O OE1 . GLU A 1 132 ? 169.940 199.312 214.909 1.00 33.01  ? 153 GLU A OE1 1 
ATOM   984   O OE2 . GLU A 1 132 ? 171.826 200.126 214.127 1.00 33.01  ? 153 GLU A OE2 1 
ATOM   985   N N   . GLN A 1 133 ? 167.579 200.727 210.752 1.00 42.57  ? 154 GLN A N   1 
ATOM   986   C CA  . GLN A 1 133 ? 167.340 201.945 209.996 1.00 42.57  ? 154 GLN A CA  1 
ATOM   987   C C   . GLN A 1 133 ? 167.987 203.137 210.691 1.00 42.57  ? 154 GLN A C   1 
ATOM   988   O O   . GLN A 1 133 ? 168.127 203.163 211.917 1.00 42.57  ? 154 GLN A O   1 
ATOM   989   C CB  . GLN A 1 133 ? 165.838 202.197 209.845 1.00 42.57  ? 154 GLN A CB  1 
ATOM   990   C CG  . GLN A 1 133 ? 165.073 201.037 209.230 1.00 42.57  ? 154 GLN A CG  1 
ATOM   991   C CD  . GLN A 1 133 ? 165.303 200.909 207.742 1.00 42.57  ? 154 GLN A CD  1 
ATOM   992   O OE1 . GLN A 1 133 ? 165.095 201.859 206.989 1.00 42.57  ? 154 GLN A OE1 1 
ATOM   993   N NE2 . GLN A 1 133 ? 165.731 199.730 207.308 1.00 42.57  ? 154 GLN A NE2 1 
ATOM   994   N N   . LEU A 1 134 ? 168.388 204.121 209.889 1.00 50.50  ? 155 LEU A N   1 
ATOM   995   C CA  . LEU A 1 134 ? 168.879 205.398 210.385 1.00 50.50  ? 155 LEU A CA  1 
ATOM   996   C C   . LEU A 1 134 ? 168.151 206.518 209.656 1.00 50.50  ? 155 LEU A C   1 
ATOM   997   O O   . LEU A 1 134 ? 167.778 206.377 208.489 1.00 50.50  ? 155 LEU A O   1 
ATOM   998   C CB  . LEU A 1 134 ? 170.395 205.551 210.189 1.00 50.50  ? 155 LEU A CB  1 
ATOM   999   C CG  . LEU A 1 134 ? 171.304 204.474 210.779 1.00 50.50  ? 155 LEU A CG  1 
ATOM   1000  C CD1 . LEU A 1 134 ? 172.714 204.611 210.228 1.00 50.50  ? 155 LEU A CD1 1 
ATOM   1001  C CD2 . LEU A 1 134 ? 171.307 204.550 212.296 1.00 50.50  ? 155 LEU A CD2 1 
ATOM   1002  N N   . SER A 1 135 ? 167.958 207.634 210.354 1.00 61.66  ? 156 SER A N   1 
ATOM   1003  C CA  . SER A 1 135 ? 167.197 208.762 209.819 1.00 61.66  ? 156 SER A CA  1 
ATOM   1004  C C   . SER A 1 135 ? 168.082 209.553 208.865 1.00 61.66  ? 156 SER A C   1 
ATOM   1005  O O   . SER A 1 135 ? 168.945 210.324 209.292 1.00 61.66  ? 156 SER A O   1 
ATOM   1006  C CB  . SER A 1 135 ? 166.679 209.640 210.951 1.00 61.66  ? 156 SER A CB  1 
ATOM   1007  O OG  . SER A 1 135 ? 165.772 208.927 211.772 1.00 61.66  ? 156 SER A OG  1 
ATOM   1008  N N   . LEU A 1 136 ? 167.869 209.357 207.562 1.00 66.10  ? 157 LEU A N   1 
ATOM   1009  C CA  . LEU A 1 136 ? 168.641 210.093 206.565 1.00 66.10  ? 157 LEU A CA  1 
ATOM   1010  C C   . LEU A 1 136 ? 168.181 211.541 206.460 1.00 66.10  ? 157 LEU A C   1 
ATOM   1011  O O   . LEU A 1 136 ? 169.008 212.457 206.373 1.00 66.10  ? 157 LEU A O   1 
ATOM   1012  C CB  . LEU A 1 136 ? 168.538 209.400 205.206 1.00 66.10  ? 157 LEU A CB  1 
ATOM   1013  C CG  . LEU A 1 136 ? 169.385 209.983 204.075 1.00 66.10  ? 157 LEU A CG  1 
ATOM   1014  C CD1 . LEU A 1 136 ? 170.841 210.108 204.497 1.00 66.10  ? 157 LEU A CD1 1 
ATOM   1015  C CD2 . LEU A 1 136 ? 169.256 209.140 202.816 1.00 66.10  ? 157 LEU A CD2 1 
ATOM   1016  N N   . GLY A 1 137 ? 166.878 211.769 206.467 1.00 78.88  ? 158 GLY A N   1 
ATOM   1017  C CA  . GLY A 1 137 ? 166.320 213.104 206.333 1.00 78.88  ? 158 GLY A CA  1 
ATOM   1018  C C   . GLY A 1 137 ? 165.039 213.228 207.123 1.00 78.88  ? 158 GLY A C   1 
ATOM   1019  O O   . GLY A 1 137 ? 164.826 212.506 208.103 1.00 78.88  ? 158 GLY A O   1 
ATOM   1020  N N   . VAL A 1 138 ? 164.178 214.155 206.697 1.00 84.94  ? 159 VAL A N   1 
ATOM   1021  C CA  . VAL A 1 138 ? 162.912 214.354 207.395 1.00 84.94  ? 159 VAL A CA  1 
ATOM   1022  C C   . VAL A 1 138 ? 161.920 213.247 207.055 1.00 84.94  ? 159 VAL A C   1 
ATOM   1023  O O   . VAL A 1 138 ? 161.029 212.938 207.856 1.00 84.94  ? 159 VAL A O   1 
ATOM   1024  C CB  . VAL A 1 138 ? 162.346 215.756 207.090 1.00 84.94  ? 159 VAL A CB  1 
ATOM   1025  C CG1 . VAL A 1 138 ? 163.269 216.825 207.650 1.00 84.94  ? 159 VAL A CG1 1 
ATOM   1026  C CG2 . VAL A 1 138 ? 162.158 215.962 205.592 1.00 84.94  ? 159 VAL A CG2 1 
ATOM   1027  N N   . GLN A 1 139 ? 162.051 212.629 205.877 1.00 85.94  ? 160 GLN A N   1 
ATOM   1028  C CA  . GLN A 1 139 ? 161.184 211.526 205.487 1.00 85.94  ? 160 GLN A CA  1 
ATOM   1029  C C   . GLN A 1 139 ? 161.931 210.375 204.831 1.00 85.94  ? 160 GLN A C   1 
ATOM   1030  O O   . GLN A 1 139 ? 161.298 209.369 204.494 1.00 85.94  ? 160 GLN A O   1 
ATOM   1031  C CB  . GLN A 1 139 ? 160.077 212.013 204.534 1.00 85.94  ? 160 GLN A CB  1 
ATOM   1032  C CG  . GLN A 1 139 ? 158.952 212.783 205.210 1.00 85.94  ? 160 GLN A CG  1 
ATOM   1033  C CD  . GLN A 1 139 ? 158.173 211.930 206.192 1.00 85.94  ? 160 GLN A CD  1 
ATOM   1034  O OE1 . GLN A 1 139 ? 158.205 212.167 207.400 1.00 85.94  ? 160 GLN A OE1 1 
ATOM   1035  N NE2 . GLN A 1 139 ? 157.468 210.929 205.678 1.00 85.94  ? 160 GLN A NE2 1 
ATOM   1036  N N   . GLU A 1 140 ? 163.241 210.482 204.639 1.00 78.35  ? 161 GLU A N   1 
ATOM   1037  C CA  . GLU A 1 140 ? 164.034 209.443 204.004 1.00 78.35  ? 161 GLU A CA  1 
ATOM   1038  C C   . GLU A 1 140 ? 164.876 208.722 205.046 1.00 78.35  ? 161 GLU A C   1 
ATOM   1039  O O   . GLU A 1 140 ? 165.299 209.311 206.045 1.00 78.35  ? 161 GLU A O   1 
ATOM   1040  C CB  . GLU A 1 140 ? 164.941 210.027 202.918 1.00 78.35  ? 161 GLU A CB  1 
ATOM   1041  C CG  . GLU A 1 140 ? 164.221 210.911 201.916 1.00 78.35  ? 161 GLU A CG  1 
ATOM   1042  C CD  . GLU A 1 140 ? 164.396 212.387 202.216 1.00 78.35  ? 161 GLU A CD  1 
ATOM   1043  O OE1 . GLU A 1 140 ? 164.052 212.810 203.340 1.00 78.35  ? 161 GLU A OE1 1 
ATOM   1044  O OE2 . GLU A 1 140 ? 164.878 213.122 201.329 1.00 78.35  ? 161 GLU A OE2 1 
ATOM   1045  N N   . THR A 1 141 ? 165.112 207.435 204.806 1.00 60.03  ? 162 THR A N   1 
ATOM   1046  C CA  . THR A 1 141 ? 165.894 206.616 205.717 1.00 60.03  ? 162 THR A CA  1 
ATOM   1047  C C   . THR A 1 141 ? 166.796 205.686 204.919 1.00 60.03  ? 162 THR A C   1 
ATOM   1048  O O   . THR A 1 141 ? 166.539 205.385 203.751 1.00 60.03  ? 162 THR A O   1 
ATOM   1049  C CB  . THR A 1 141 ? 164.997 205.800 206.659 1.00 60.03  ? 162 THR A CB  1 
ATOM   1050  O OG1 . THR A 1 141 ? 165.806 204.916 207.445 1.00 60.03  ? 162 THR A OG1 1 
ATOM   1051  C CG2 . THR A 1 141 ? 163.982 204.987 205.869 1.00 60.03  ? 162 THR A CG2 1 
ATOM   1052  N N   . VAL A 1 142 ? 167.870 205.245 205.563 1.00 45.32  ? 163 VAL A N   1 
ATOM   1053  C CA  . VAL A 1 142 ? 168.749 204.243 204.996 1.00 45.32  ? 163 VAL A CA  1 
ATOM   1054  C C   . VAL A 1 142 ? 168.460 202.913 205.676 1.00 45.32  ? 163 VAL A C   1 
ATOM   1055  O O   . VAL A 1 142 ? 167.818 202.842 206.727 1.00 45.32  ? 163 VAL A O   1 
ATOM   1056  C CB  . VAL A 1 142 ? 170.242 204.620 205.125 1.00 45.32  ? 163 VAL A CB  1 
ATOM   1057  C CG1 . VAL A 1 142 ? 170.514 205.943 204.435 1.00 45.32  ? 163 VAL A CG1 1 
ATOM   1058  C CG2 . VAL A 1 142 ? 170.651 204.675 206.582 1.00 45.32  ? 163 VAL A CG2 1 
ATOM   1059  N N   . SER A 1 143 ? 168.953 201.842 205.069 1.00 37.51  ? 164 SER A N   1 
ATOM   1060  C CA  . SER A 1 143 ? 168.639 200.469 205.446 1.00 37.51  ? 164 SER A CA  1 
ATOM   1061  C C   . SER A 1 143 ? 169.920 199.671 205.634 1.00 37.51  ? 164 SER A C   1 
ATOM   1062  O O   . SER A 1 143 ? 170.149 198.666 204.955 1.00 37.51  ? 164 SER A O   1 
ATOM   1063  C CB  . SER A 1 143 ? 167.724 199.817 204.415 1.00 37.51  ? 164 SER A CB  1 
ATOM   1064  O OG  . SER A 1 143 ? 168.338 199.786 203.142 1.00 37.51  ? 164 SER A OG  1 
ATOM   1065  N N   . VAL A 1 144 ? 170.809 200.189 206.495 1.00 25.89  ? 165 VAL A N   1 
ATOM   1066  C CA  . VAL A 1 144 ? 172.103 199.565 206.776 1.00 25.89  ? 165 VAL A CA  1 
ATOM   1067  C C   . VAL A 1 144 ? 171.916 198.141 207.293 1.00 25.89  ? 165 VAL A C   1 
ATOM   1068  O O   . VAL A 1 144 ? 171.002 197.850 208.076 1.00 25.89  ? 165 VAL A O   1 
ATOM   1069  C CB  . VAL A 1 144 ? 172.915 200.455 207.739 1.00 25.89  ? 165 VAL A CB  1 
ATOM   1070  C CG1 . VAL A 1 144 ? 172.244 200.621 209.103 1.00 25.89  ? 165 VAL A CG1 1 
ATOM   1071  C CG2 . VAL A 1 144 ? 174.343 199.944 207.896 1.00 25.89  ? 165 VAL A CG2 1 
ATOM   1072  N N   . LEU A 1 145 ? 172.733 197.225 206.775 1.00 26.26  ? 166 LEU A N   1 
ATOM   1073  C CA  . LEU A 1 145 ? 172.509 195.803 206.968 1.00 26.26  ? 166 LEU A CA  1 
ATOM   1074  C C   . LEU A 1 145 ? 173.830 195.046 206.985 1.00 26.26  ? 166 LEU A C   1 
ATOM   1075  O O   . LEU A 1 145 ? 174.725 195.317 206.180 1.00 26.26  ? 166 LEU A O   1 
ATOM   1076  C CB  . LEU A 1 145 ? 171.547 195.270 205.887 1.00 26.26  ? 166 LEU A CB  1 
ATOM   1077  C CG  . LEU A 1 145 ? 171.797 195.427 204.381 1.00 26.26  ? 166 LEU A CG  1 
ATOM   1078  C CD1 . LEU A 1 145 ? 172.630 194.312 203.785 1.00 26.26  ? 166 LEU A CD1 1 
ATOM   1079  C CD2 . LEU A 1 145 ? 170.473 195.556 203.637 1.00 26.26  ? 166 LEU A CD2 1 
ATOM   1080  N N   . MET A 1 146 ? 173.941 194.105 207.922 1.00 47.53  ? 167 MET A N   1 
ATOM   1081  C CA  . MET A 1 146 ? 175.102 193.241 208.076 1.00 47.53  ? 167 MET A CA  1 
ATOM   1082  C C   . MET A 1 146 ? 174.636 191.813 208.313 1.00 47.53  ? 167 MET A C   1 
ATOM   1083  O O   . MET A 1 146 ? 173.728 191.576 209.114 1.00 47.53  ? 167 MET A O   1 
ATOM   1084  C CB  . MET A 1 146 ? 175.992 193.703 209.238 1.00 47.53  ? 167 MET A CB  1 
ATOM   1085  C CG  . MET A 1 146 ? 177.285 192.922 209.393 1.00 47.53  ? 167 MET A CG  1 
ATOM   1086  S SD  . MET A 1 146 ? 178.436 193.110 208.028 1.00 47.53  ? 167 MET A SD  1 
ATOM   1087  C CE  . MET A 1 146 ? 179.378 191.598 208.187 1.00 47.53  ? 167 MET A CE  1 
ATOM   1088  N N   . GLY A 1 147 ? 175.261 190.865 207.620 1.00 41.21  ? 168 GLY A N   1 
ATOM   1089  C CA  . GLY A 1 147 ? 174.864 189.476 207.731 1.00 41.21  ? 168 GLY A CA  1 
ATOM   1090  C C   . GLY A 1 147 ? 175.414 188.748 208.938 1.00 41.21  ? 168 GLY A C   1 
ATOM   1091  O O   . GLY A 1 147 ? 174.692 187.996 209.598 1.00 41.21  ? 168 GLY A O   1 
ATOM   1092  N N   . LEU A 1 148 ? 176.692 188.957 209.237 1.00 40.37  ? 169 LEU A N   1 
ATOM   1093  C CA  . LEU A 1 148 ? 177.343 188.277 210.348 1.00 40.37  ? 169 LEU A CA  1 
ATOM   1094  C C   . LEU A 1 148 ? 177.108 188.958 211.686 1.00 40.37  ? 169 LEU A C   1 
ATOM   1095  O O   . LEU A 1 148 ? 177.529 188.417 212.711 1.00 40.37  ? 169 LEU A O   1 
ATOM   1096  C CB  . LEU A 1 148 ? 178.853 188.157 210.104 1.00 40.37  ? 169 LEU A CB  1 
ATOM   1097  C CG  . LEU A 1 148 ? 179.379 186.940 209.336 1.00 40.37  ? 169 LEU A CG  1 
ATOM   1098  C CD1 . LEU A 1 148 ? 179.051 187.002 207.856 1.00 40.37  ? 169 LEU A CD1 1 
ATOM   1099  C CD2 . LEU A 1 148 ? 180.878 186.801 209.548 1.00 40.37  ? 169 LEU A CD2 1 
ATOM   1100  N N   . GLN A 1 149 ? 176.434 190.112 211.706 1.00 47.60  ? 170 GLN A N   1 
ATOM   1101  C CA  . GLN A 1 149 ? 176.190 190.822 212.958 1.00 47.60  ? 170 GLN A CA  1 
ATOM   1102  C C   . GLN A 1 149 ? 175.251 190.063 213.886 1.00 47.60  ? 170 GLN A C   1 
ATOM   1103  O O   . GLN A 1 149 ? 175.297 190.275 215.101 1.00 47.60  ? 170 GLN A O   1 
ATOM   1104  C CB  . GLN A 1 149 ? 175.627 192.215 212.673 1.00 47.60  ? 170 GLN A CB  1 
ATOM   1105  C CG  . GLN A 1 149 ? 175.915 193.240 213.760 1.00 47.60  ? 170 GLN A CG  1 
ATOM   1106  C CD  . GLN A 1 149 ? 177.300 193.092 214.356 1.00 47.60  ? 170 GLN A CD  1 
ATOM   1107  O OE1 . GLN A 1 149 ? 178.305 193.331 213.686 1.00 47.60  ? 170 GLN A OE1 1 
ATOM   1108  N NE2 . GLN A 1 149 ? 177.360 192.700 215.623 1.00 47.60  ? 170 GLN A NE2 1 
ATOM   1109  N N   . ASP A 1 150 ? 174.413 189.176 213.348 1.00 60.96  ? 171 ASP A N   1 
ATOM   1110  C CA  . ASP A 1 150 ? 173.622 188.300 214.203 1.00 60.96  ? 171 ASP A CA  1 
ATOM   1111  C C   . ASP A 1 150 ? 174.487 187.215 214.836 1.00 60.96  ? 171 ASP A C   1 
ATOM   1112  O O   . ASP A 1 150 ? 174.296 186.869 216.007 1.00 60.96  ? 171 ASP A O   1 
ATOM   1113  C CB  . ASP A 1 150 ? 172.480 187.678 213.403 1.00 60.96  ? 171 ASP A CB  1 
ATOM   1114  C CG  . ASP A 1 150 ? 171.568 186.826 214.258 1.00 60.96  ? 171 ASP A CG  1 
ATOM   1115  O OD1 . ASP A 1 150 ? 170.787 187.399 215.047 1.00 60.96  ? 171 ASP A OD1 1 
ATOM   1116  O OD2 . ASP A 1 150 ? 171.632 185.584 214.144 1.00 60.96  ? 171 ASP A OD2 1 
ATOM   1117  N N   . GLN A 1 151 ? 175.452 186.677 214.085 1.00 50.86  ? 172 GLN A N   1 
ATOM   1118  C CA  . GLN A 1 151 ? 176.212 185.518 214.542 1.00 50.86  ? 172 GLN A CA  1 
ATOM   1119  C C   . GLN A 1 151 ? 177.273 185.858 215.582 1.00 50.86  ? 172 GLN A C   1 
ATOM   1120  O O   . GLN A 1 151 ? 177.777 184.946 216.246 1.00 50.86  ? 172 GLN A O   1 
ATOM   1121  C CB  . GLN A 1 151 ? 176.862 184.812 213.352 1.00 50.86  ? 172 GLN A CB  1 
ATOM   1122  C CG  . GLN A 1 151 ? 175.868 184.093 212.456 1.00 50.86  ? 172 GLN A CG  1 
ATOM   1123  C CD  . GLN A 1 151 ? 176.538 183.281 211.370 1.00 50.86  ? 172 GLN A CD  1 
ATOM   1124  O OE1 . GLN A 1 151 ? 177.761 183.289 211.238 1.00 50.86  ? 172 GLN A OE1 1 
ATOM   1125  N NE2 . GLN A 1 151 ? 175.739 182.572 210.582 1.00 50.86  ? 172 GLN A NE2 1 
ATOM   1126  N N   . ILE A 1 152 ? 177.626 187.132 215.742 1.00 51.96  ? 173 ILE A N   1 
ATOM   1127  C CA  . ILE A 1 152 ? 178.473 187.547 216.857 1.00 51.96  ? 173 ILE A CA  1 
ATOM   1128  C C   . ILE A 1 152 ? 177.587 188.452 217.716 1.00 51.96  ? 173 ILE A C   1 
ATOM   1129  O O   . ILE A 1 152 ? 178.013 189.495 218.226 1.00 51.96  ? 173 ILE A O   1 
ATOM   1130  C CB  . ILE A 1 152 ? 179.794 188.207 216.398 1.00 51.96  ? 173 ILE A CB  1 
ATOM   1131  C CG1 . ILE A 1 152 ? 180.513 187.334 215.373 1.00 51.96  ? 173 ILE A CG1 1 
ATOM   1132  C CG2 . ILE A 1 152 ? 180.835 188.234 217.517 1.00 51.96  ? 173 ILE A CG2 1 
ATOM   1133  C CD1 . ILE A 1 152 ? 180.466 187.837 213.964 1.00 51.96  ? 173 ILE A CD1 1 
ATOM   1134  N N   . ASN A 1 153 ? 176.305 188.096 217.798 1.00 58.50  ? 174 ASN A N   1 
ATOM   1135  C CA  . ASN A 1 153 ? 175.432 188.619 218.840 1.00 58.50  ? 174 ASN A CA  1 
ATOM   1136  C C   . ASN A 1 153 ? 174.526 187.564 219.458 1.00 58.50  ? 174 ASN A C   1 
ATOM   1137  O O   . ASN A 1 153 ? 173.785 187.889 220.390 1.00 58.50  ? 174 ASN A O   1 
ATOM   1138  C CB  . ASN A 1 153 ? 174.573 189.780 218.312 1.00 58.50  ? 174 ASN A CB  1 
ATOM   1139  C CG  . ASN A 1 153 ? 175.242 191.128 218.497 1.00 58.50  ? 174 ASN A CG  1 
ATOM   1140  O OD1 . ASN A 1 153 ? 175.542 191.827 217.531 1.00 58.50  ? 174 ASN A OD1 1 
ATOM   1141  N ND2 . ASN A 1 153 ? 175.476 191.501 219.749 1.00 58.50  ? 174 ASN A ND2 1 
ATOM   1142  N N   . THR A 1 154 ? 174.553 186.320 218.976 1.00 59.88  ? 175 THR A N   1 
ATOM   1143  C CA  . THR A 1 154 ? 173.779 185.254 219.600 1.00 59.88  ? 175 THR A CA  1 
ATOM   1144  C C   . THR A 1 154 ? 174.532 183.942 219.752 1.00 59.88  ? 175 THR A C   1 
ATOM   1145  O O   . THR A 1 154 ? 174.041 183.064 220.467 1.00 59.88  ? 175 THR A O   1 
ATOM   1146  C CB  . THR A 1 154 ? 172.482 184.990 218.817 1.00 59.88  ? 175 THR A CB  1 
ATOM   1147  O OG1 . THR A 1 154 ? 171.628 184.135 219.584 1.00 59.88  ? 175 THR A OG1 1 
ATOM   1148  C CG2 . THR A 1 154 ? 172.776 184.318 217.484 1.00 59.88  ? 175 THR A CG2 1 
ATOM   1149  N N   . ASN A 1 155 ? 175.691 183.766 219.120 1.00 62.89  ? 176 ASN A N   1 
ATOM   1150  C CA  . ASN A 1 155 ? 176.416 182.503 219.173 1.00 62.89  ? 176 ASN A CA  1 
ATOM   1151  C C   . ASN A 1 155 ? 177.780 182.633 219.828 1.00 62.89  ? 176 ASN A C   1 
ATOM   1152  O O   . ASN A 1 155 ? 178.079 181.896 220.774 1.00 62.89  ? 176 ASN A O   1 
ATOM   1153  C CB  . ASN A 1 155 ? 176.569 181.926 217.757 1.00 62.89  ? 176 ASN A CB  1 
ATOM   1154  C CG  . ASN A 1 155 ? 177.606 180.824 217.689 1.00 62.89  ? 176 ASN A CG  1 
ATOM   1155  O OD1 . ASN A 1 155 ? 177.447 179.768 218.301 1.00 62.89  ? 176 ASN A OD1 1 
ATOM   1156  N ND2 . ASN A 1 155 ? 178.678 181.066 216.944 1.00 62.89  ? 176 ASN A ND2 1 
ATOM   1157  N N   . LEU A 1 156 ? 178.624 183.550 219.351 1.00 56.10  ? 177 LEU A N   1 
ATOM   1158  C CA  . LEU A 1 156 ? 179.959 183.701 219.918 1.00 56.10  ? 177 LEU A CA  1 
ATOM   1159  C C   . LEU A 1 156 ? 179.944 184.490 221.221 1.00 56.10  ? 177 LEU A C   1 
ATOM   1160  O O   . LEU A 1 156 ? 180.807 184.276 222.079 1.00 56.10  ? 177 LEU A O   1 
ATOM   1161  C CB  . LEU A 1 156 ? 180.881 184.373 218.901 1.00 56.10  ? 177 LEU A CB  1 
ATOM   1162  C CG  . LEU A 1 156 ? 182.359 183.992 218.964 1.00 56.10  ? 177 LEU A CG  1 
ATOM   1163  C CD1 . LEU A 1 156 ? 182.544 182.540 218.564 1.00 56.10  ? 177 LEU A CD1 1 
ATOM   1164  C CD2 . LEU A 1 156 ? 183.176 184.898 218.064 1.00 56.10  ? 177 LEU A CD2 1 
ATOM   1165  N N   . VAL A 1 157 ? 178.992 185.406 221.376 1.00 60.33  ? 178 VAL A N   1 
ATOM   1166  C CA  . VAL A 1 157 ? 178.826 186.218 222.584 1.00 60.33  ? 178 VAL A CA  1 
ATOM   1167  C C   . VAL A 1 157 ? 178.493 185.408 223.846 1.00 60.33  ? 178 VAL A C   1 
ATOM   1168  O O   . VAL A 1 157 ? 179.153 185.655 224.868 1.00 60.33  ? 178 VAL A O   1 
ATOM   1169  C CB  . VAL A 1 157 ? 177.801 187.343 222.330 1.00 60.33  ? 178 VAL A CB  1 
ATOM   1170  C CG1 . VAL A 1 157 ? 177.480 188.121 223.601 1.00 60.33  ? 178 VAL A CG1 1 
ATOM   1171  C CG2 . VAL A 1 157 ? 178.330 188.285 221.275 1.00 60.33  ? 178 VAL A CG2 1 
ATOM   1172  N N   . PRO A 1 158 ? 177.529 184.454 223.878 1.00 58.29  ? 179 PRO A N   1 
ATOM   1173  C CA  . PRO A 1 158 ? 177.265 183.756 225.157 1.00 58.29  ? 179 PRO A CA  1 
ATOM   1174  C C   . PRO A 1 158 ? 178.392 182.853 225.644 1.00 58.29  ? 179 PRO A C   1 
ATOM   1175  O O   . PRO A 1 158 ? 178.428 182.540 226.840 1.00 58.29  ? 179 PRO A O   1 
ATOM   1176  C CB  . PRO A 1 158 ? 176.001 182.938 224.859 1.00 58.29  ? 179 PRO A CB  1 
ATOM   1177  C CG  . PRO A 1 158 ? 175.361 183.640 223.745 1.00 58.29  ? 179 PRO A CG  1 
ATOM   1178  C CD  . PRO A 1 158 ? 176.514 184.024 222.889 1.00 58.29  ? 179 PRO A CD  1 
ATOM   1179  N N   . LYS A 1 159 ? 179.304 182.426 224.778 1.00 61.54  ? 180 LYS A N   1 
ATOM   1180  C CA  . LYS A 1 159 ? 180.486 181.682 225.215 1.00 61.54  ? 180 LYS A CA  1 
ATOM   1181  C C   . LYS A 1 159 ? 181.676 182.626 225.383 1.00 61.54  ? 180 LYS A C   1 
ATOM   1182  O O   . LYS A 1 159 ? 182.722 182.481 224.752 1.00 61.54  ? 180 LYS A O   1 
ATOM   1183  C CB  . LYS A 1 159 ? 180.799 180.555 224.234 1.00 61.54  ? 180 LYS A CB  1 
ATOM   1184  C CG  . LYS A 1 159 ? 180.532 180.892 222.780 1.00 61.54  ? 180 LYS A CG  1 
ATOM   1185  C CD  . LYS A 1 159 ? 180.589 179.645 221.912 1.00 61.54  ? 180 LYS A CD  1 
ATOM   1186  C CE  . LYS A 1 159 ? 179.299 178.847 222.005 1.00 61.54  ? 180 LYS A CE  1 
ATOM   1187  N NZ  . LYS A 1 159 ? 179.167 177.871 220.888 1.00 61.54  ? 180 LYS A NZ  1 
ATOM   1188  N N   . ILE A 1 160 ? 181.499 183.610 226.261 1.00 66.81  ? 181 ILE A N   1 
ATOM   1189  C CA  . ILE A 1 160 ? 182.541 184.604 226.489 1.00 66.81  ? 181 ILE A CA  1 
ATOM   1190  C C   . ILE A 1 160 ? 183.516 184.165 227.587 1.00 66.81  ? 181 ILE A C   1 
ATOM   1191  O O   . ILE A 1 160 ? 184.696 184.530 227.550 1.00 66.81  ? 181 ILE A O   1 
ATOM   1192  C CB  . ILE A 1 160 ? 181.892 185.974 226.791 1.00 66.81  ? 181 ILE A CB  1 
ATOM   1193  C CG1 . ILE A 1 160 ? 182.920 187.111 226.785 1.00 66.81  ? 181 ILE A CG1 1 
ATOM   1194  C CG2 . ILE A 1 160 ? 181.073 185.956 228.085 1.00 66.81  ? 181 ILE A CG2 1 
ATOM   1195  C CD1 . ILE A 1 160 ? 182.301 188.485 226.798 1.00 66.81  ? 181 ILE A CD1 1 
ATOM   1196  N N   . ASN A 1 161 ? 183.070 183.341 228.536 1.00 67.86  ? 182 ASN A N   1 
ATOM   1197  C CA  . ASN A 1 161 ? 183.925 182.889 229.626 1.00 67.86  ? 182 ASN A CA  1 
ATOM   1198  C C   . ASN A 1 161 ? 183.932 181.384 229.827 1.00 67.86  ? 182 ASN A C   1 
ATOM   1199  O O   . ASN A 1 161 ? 184.827 180.883 230.518 1.00 67.86  ? 182 ASN A O   1 
ATOM   1200  C CB  . ASN A 1 161 ? 183.512 183.560 230.945 1.00 67.86  ? 182 ASN A CB  1 
ATOM   1201  C CG  . ASN A 1 161 ? 183.978 184.999 231.035 1.00 67.86  ? 182 ASN A CG  1 
ATOM   1202  O OD1 . ASN A 1 161 ? 184.999 185.370 230.454 1.00 67.86  ? 182 ASN A OD1 1 
ATOM   1203  N ND2 . ASN A 1 161 ? 183.231 185.818 231.764 1.00 67.86  ? 182 ASN A ND2 1 
ATOM   1204  N N   . ILE A 1 162 ? 182.968 180.650 229.268 1.00 74.03  ? 183 ILE A N   1 
ATOM   1205  C CA  . ILE A 1 162 ? 182.993 179.194 229.348 1.00 74.03  ? 183 ILE A CA  1 
ATOM   1206  C C   . ILE A 1 162 ? 184.117 178.637 228.481 1.00 74.03  ? 183 ILE A C   1 
ATOM   1207  O O   . ILE A 1 162 ? 184.817 177.694 228.871 1.00 74.03  ? 183 ILE A O   1 
ATOM   1208  C CB  . ILE A 1 162 ? 181.622 178.619 228.945 1.00 74.03  ? 183 ILE A CB  1 
ATOM   1209  C CG1 . ILE A 1 162 ? 180.500 179.309 229.726 1.00 74.03  ? 183 ILE A CG1 1 
ATOM   1210  C CG2 . ILE A 1 162 ? 181.572 177.117 229.178 1.00 74.03  ? 183 ILE A CG2 1 
ATOM   1211  C CD1 . ILE A 1 162 ? 180.605 179.150 231.231 1.00 74.03  ? 183 ILE A CD1 1 
ATOM   1212  N N   . LEU A 1 163 ? 184.321 179.225 227.309 1.00 69.46  ? 184 LEU A N   1 
ATOM   1213  C CA  . LEU A 1 163 ? 185.333 178.791 226.361 1.00 69.46  ? 184 LEU A CA  1 
ATOM   1214  C C   . LEU A 1 163 ? 186.592 179.641 226.505 1.00 69.46  ? 184 LEU A C   1 
ATOM   1215  O O   . LEU A 1 163 ? 186.533 180.805 226.911 1.00 69.46  ? 184 LEU A O   1 
ATOM   1216  C CB  . LEU A 1 163 ? 184.789 178.879 224.935 1.00 69.46  ? 184 LEU A CB  1 
ATOM   1217  C CG  . LEU A 1 163 ? 185.414 178.010 223.847 1.00 69.46  ? 184 LEU A CG  1 
ATOM   1218  C CD1 . LEU A 1 163 ? 184.924 176.580 223.966 1.00 69.46  ? 184 LEU A CD1 1 
ATOM   1219  C CD2 . LEU A 1 163 ? 185.054 178.582 222.493 1.00 69.46  ? 184 LEU A CD2 1 
ATOM   1220  N N   . SER A 1 164 ? 187.735 179.040 226.180 1.00 73.18  ? 185 SER A N   1 
ATOM   1221  C CA  . SER A 1 164 ? 189.014 179.731 226.281 1.00 73.18  ? 185 SER A CA  1 
ATOM   1222  C C   . SER A 1 164 ? 189.144 180.795 225.196 1.00 73.18  ? 185 SER A C   1 
ATOM   1223  O O   . SER A 1 164 ? 188.596 180.663 224.100 1.00 73.18  ? 185 SER A O   1 
ATOM   1224  C CB  . SER A 1 164 ? 190.168 178.734 226.175 1.00 73.18  ? 185 SER A CB  1 
ATOM   1225  O OG  . SER A 1 164 ? 190.219 178.151 224.885 1.00 73.18  ? 185 SER A OG  1 
ATOM   1226  N N   . CYS A 1 165 ? 189.902 181.853 225.516 1.00 81.44  ? 186 CYS A N   1 
ATOM   1227  C CA  . CYS A 1 165 ? 189.971 183.038 224.662 1.00 81.44  ? 186 CYS A CA  1 
ATOM   1228  C C   . CYS A 1 165 ? 190.682 182.762 223.341 1.00 81.44  ? 186 CYS A C   1 
ATOM   1229  O O   . CYS A 1 165 ? 190.319 183.345 222.309 1.00 81.44  ? 186 CYS A O   1 
ATOM   1230  C CB  . CYS A 1 165 ? 190.669 184.175 225.409 1.00 81.44  ? 186 CYS A CB  1 
ATOM   1231  S SG  . CYS A 1 165 ? 189.853 184.672 226.949 1.00 81.44  ? 186 CYS A SG  1 
ATOM   1232  N N   . LYS A 1 166 ? 191.685 181.877 223.348 1.00 78.72  ? 187 LYS A N   1 
ATOM   1233  C CA  . LYS A 1 166 ? 192.344 181.503 222.102 1.00 78.72  ? 187 LYS A CA  1 
ATOM   1234  C C   . LYS A 1 166 ? 191.418 180.695 221.199 1.00 78.72  ? 187 LYS A C   1 
ATOM   1235  O O   . LYS A 1 166 ? 191.537 180.768 219.971 1.00 78.72  ? 187 LYS A O   1 
ATOM   1236  C CB  . LYS A 1 166 ? 193.635 180.733 222.393 1.00 78.72  ? 187 LYS A CB  1 
ATOM   1237  C CG  . LYS A 1 166 ? 193.459 179.438 223.173 1.00 78.72  ? 187 LYS A CG  1 
ATOM   1238  C CD  . LYS A 1 166 ? 194.792 178.746 223.403 1.00 78.72  ? 187 LYS A CD  1 
ATOM   1239  C CE  . LYS A 1 166 ? 194.624 177.482 224.231 1.00 78.72  ? 187 LYS A CE  1 
ATOM   1240  N NZ  . LYS A 1 166 ? 193.842 176.444 223.504 1.00 78.72  ? 187 LYS A NZ  1 
ATOM   1241  N N   . GLN A 1 167 ? 190.465 179.961 221.782 1.00 75.37  ? 188 GLN A N   1 
ATOM   1242  C CA  . GLN A 1 167 ? 189.481 179.252 220.971 1.00 75.37  ? 188 GLN A CA  1 
ATOM   1243  C C   . GLN A 1 167 ? 188.503 180.224 220.320 1.00 75.37  ? 188 GLN A C   1 
ATOM   1244  O O   . GLN A 1 167 ? 188.098 180.020 219.169 1.00 75.37  ? 188 GLN A O   1 
ATOM   1245  C CB  . GLN A 1 167 ? 188.742 178.222 221.825 1.00 75.37  ? 188 GLN A CB  1 
ATOM   1246  C CG  . GLN A 1 167 ? 188.125 177.047 221.058 1.00 75.37  ? 188 GLN A CG  1 
ATOM   1247  C CD  . GLN A 1 167 ? 189.151 176.072 220.495 1.00 75.37  ? 188 GLN A CD  1 
ATOM   1248  O OE1 . GLN A 1 167 ? 189.824 176.349 219.500 1.00 75.37  ? 188 GLN A OE1 1 
ATOM   1249  N NE2 . GLN A 1 167 ? 189.274 174.917 221.139 1.00 75.37  ? 188 GLN A NE2 1 
ATOM   1250  N N   . LEU A 1 168 ? 188.128 181.294 221.036 1.00 68.10  ? 189 LEU A N   1 
ATOM   1251  C CA  . LEU A 1 168 ? 187.331 182.363 220.433 1.00 68.10  ? 189 LEU A CA  1 
ATOM   1252  C C   . LEU A 1 168 ? 188.086 183.056 219.308 1.00 68.10  ? 189 LEU A C   1 
ATOM   1253  O O   . LEU A 1 168 ? 187.499 183.369 218.266 1.00 68.10  ? 189 LEU A O   1 
ATOM   1254  C CB  . LEU A 1 168 ? 186.909 183.395 221.481 1.00 68.10  ? 189 LEU A CB  1 
ATOM   1255  C CG  . LEU A 1 168 ? 185.634 183.216 222.312 1.00 68.10  ? 189 LEU A CG  1 
ATOM   1256  C CD1 . LEU A 1 168 ? 185.773 182.156 223.376 1.00 68.10  ? 189 LEU A CD1 1 
ATOM   1257  C CD2 . LEU A 1 168 ? 185.235 184.545 222.936 1.00 68.10  ? 189 LEU A CD2 1 
ATOM   1258  N N   . SER A 1 169 ? 189.389 183.301 219.503 1.00 67.70  ? 190 SER A N   1 
ATOM   1259  C CA  . SER A 1 169 ? 190.199 183.925 218.457 1.00 67.70  ? 190 SER A CA  1 
ATOM   1260  C C   . SER A 1 169 ? 190.313 183.032 217.225 1.00 67.70  ? 190 SER A C   1 
ATOM   1261  O O   . SER A 1 169 ? 190.202 183.514 216.090 1.00 67.70  ? 190 SER A O   1 
ATOM   1262  C CB  . SER A 1 169 ? 191.586 184.261 219.002 1.00 67.70  ? 190 SER A CB  1 
ATOM   1263  O OG  . SER A 1 169 ? 192.407 184.821 217.992 1.00 67.70  ? 190 SER A OG  1 
ATOM   1264  N N   . ASN A 1 170 ? 190.502 181.724 217.434 1.00 64.68  ? 191 ASN A N   1 
ATOM   1265  C CA  . ASN A 1 170 ? 190.595 180.782 216.322 1.00 64.68  ? 191 ASN A CA  1 
ATOM   1266  C C   . ASN A 1 170 ? 189.270 180.657 215.575 1.00 64.68  ? 191 ASN A C   1 
ATOM   1267  O O   . ASN A 1 170 ? 189.253 180.635 214.337 1.00 64.68  ? 191 ASN A O   1 
ATOM   1268  C CB  . ASN A 1 170 ? 191.049 179.417 216.839 1.00 64.68  ? 191 ASN A CB  1 
ATOM   1269  C CG  . ASN A 1 170 ? 191.629 178.540 215.748 1.00 64.68  ? 191 ASN A CG  1 
ATOM   1270  O OD1 . ASN A 1 170 ? 191.731 178.949 214.591 1.00 64.68  ? 191 ASN A OD1 1 
ATOM   1271  N ND2 . ASN A 1 170 ? 192.014 177.323 216.112 1.00 64.68  ? 191 ASN A ND2 1 
ATOM   1272  N N   . THR A 1 171 ? 188.152 180.587 216.310 1.00 54.81  ? 192 THR A N   1 
ATOM   1273  C CA  . THR A 1 171 ? 186.836 180.494 215.683 1.00 54.81  ? 192 THR A CA  1 
ATOM   1274  C C   . THR A 1 171 ? 186.496 181.768 214.914 1.00 54.81  ? 192 THR A C   1 
ATOM   1275  O O   . THR A 1 171 ? 185.948 181.701 213.803 1.00 54.81  ? 192 THR A O   1 
ATOM   1276  C CB  . THR A 1 171 ? 185.778 180.202 216.749 1.00 54.81  ? 192 THR A CB  1 
ATOM   1277  O OG1 . THR A 1 171 ? 186.173 179.053 217.508 1.00 54.81  ? 192 THR A OG1 1 
ATOM   1278  C CG2 . THR A 1 171 ? 184.424 179.922 216.114 1.00 54.81  ? 192 THR A CG2 1 
ATOM   1279  N N   . LEU A 1 172 ? 186.846 182.932 215.476 1.00 51.17  ? 193 LEU A N   1 
ATOM   1280  C CA  . LEU A 1 172 ? 186.626 184.202 214.793 1.00 51.17  ? 193 LEU A CA  1 
ATOM   1281  C C   . LEU A 1 172 ? 187.473 184.313 213.531 1.00 51.17  ? 193 LEU A C   1 
ATOM   1282  O O   . LEU A 1 172 ? 186.996 184.815 212.508 1.00 51.17  ? 193 LEU A O   1 
ATOM   1283  C CB  . LEU A 1 172 ? 186.926 185.362 215.742 1.00 51.17  ? 193 LEU A CB  1 
ATOM   1284  C CG  . LEU A 1 172 ? 186.481 186.756 215.298 1.00 51.17  ? 193 LEU A CG  1 
ATOM   1285  C CD1 . LEU A 1 172 ? 185.033 186.744 214.838 1.00 51.17  ? 193 LEU A CD1 1 
ATOM   1286  C CD2 . LEU A 1 172 ? 186.681 187.759 216.421 1.00 51.17  ? 193 LEU A CD2 1 
ATOM   1287  N N   . ASN A 1 173 ? 188.721 183.832 213.580 1.00 46.68  ? 194 ASN A N   1 
ATOM   1288  C CA  . ASN A 1 173 ? 189.572 183.851 212.392 1.00 46.68  ? 194 ASN A CA  1 
ATOM   1289  C C   . ASN A 1 173 ? 189.052 182.915 211.305 1.00 46.68  ? 194 ASN A C   1 
ATOM   1290  O O   . ASN A 1 173 ? 189.076 183.272 210.122 1.00 46.68  ? 194 ASN A O   1 
ATOM   1291  C CB  . ASN A 1 173 ? 191.009 183.496 212.766 1.00 46.68  ? 194 ASN A CB  1 
ATOM   1292  C CG  . ASN A 1 173 ? 191.790 184.694 213.261 1.00 46.68  ? 194 ASN A CG  1 
ATOM   1293  O OD1 . ASN A 1 173 ? 191.721 185.775 212.676 1.00 46.68  ? 194 ASN A OD1 1 
ATOM   1294  N ND2 . ASN A 1 173 ? 192.536 184.512 214.343 1.00 46.68  ? 194 ASN A ND2 1 
ATOM   1295  N N   . ILE A 1 174 ? 188.563 181.729 211.686 1.00 40.47  ? 195 ILE A N   1 
ATOM   1296  C CA  . ILE A 1 174 ? 188.004 180.794 210.707 1.00 40.47  ? 195 ILE A CA  1 
ATOM   1297  C C   . ILE A 1 174 ? 186.744 181.370 210.060 1.00 40.47  ? 195 ILE A C   1 
ATOM   1298  O O   . ILE A 1 174 ? 186.584 181.323 208.828 1.00 40.47  ? 195 ILE A O   1 
ATOM   1299  C CB  . ILE A 1 174 ? 187.742 179.428 211.372 1.00 40.47  ? 195 ILE A CB  1 
ATOM   1300  C CG1 . ILE A 1 174 ? 189.060 178.712 211.684 1.00 40.47  ? 195 ILE A CG1 1 
ATOM   1301  C CG2 . ILE A 1 174 ? 186.871 178.536 210.499 1.00 40.47  ? 195 ILE A CG2 1 
ATOM   1302  C CD1 . ILE A 1 174 ? 190.039 178.661 210.525 1.00 40.47  ? 195 ILE A CD1 1 
ATOM   1303  N N   . MET A 1 175 ? 185.862 181.969 210.872 1.00 32.38  ? 196 MET A N   1 
ATOM   1304  C CA  . MET A 1 175 ? 184.637 182.574 210.351 1.00 32.38  ? 196 MET A CA  1 
ATOM   1305  C C   . MET A 1 175 ? 184.934 183.772 209.451 1.00 32.38  ? 196 MET A C   1 
ATOM   1306  O O   . MET A 1 175 ? 184.307 183.932 208.395 1.00 32.38  ? 196 MET A O   1 
ATOM   1307  C CB  . MET A 1 175 ? 183.728 182.976 211.514 1.00 32.38  ? 196 MET A CB  1 
ATOM   1308  C CG  . MET A 1 175 ? 182.474 183.738 211.116 1.00 32.38  ? 196 MET A CG  1 
ATOM   1309  S SD  . MET A 1 175 ? 181.351 184.055 212.493 1.00 32.38  ? 196 MET A SD  1 
ATOM   1310  C CE  . MET A 1 175 ? 181.568 182.579 213.484 1.00 32.38  ? 196 MET A CE  1 
ATOM   1311  N N   . LEU A 1 176 ? 185.918 184.599 209.822 1.00 30.43  ? 197 LEU A N   1 
ATOM   1312  C CA  . LEU A 1 176 ? 186.251 185.760 209.005 1.00 30.43  ? 197 LEU A CA  1 
ATOM   1313  C C   . LEU A 1 176 ? 186.956 185.373 207.709 1.00 30.43  ? 197 LEU A C   1 
ATOM   1314  O O   . LEU A 1 176 ? 186.744 186.027 206.684 1.00 30.43  ? 197 LEU A O   1 
ATOM   1315  C CB  . LEU A 1 176 ? 187.104 186.742 209.805 1.00 30.43  ? 197 LEU A CB  1 
ATOM   1316  C CG  . LEU A 1 176 ? 186.328 187.603 210.802 1.00 30.43  ? 197 LEU A CG  1 
ATOM   1317  C CD1 . LEU A 1 176 ? 187.277 188.423 211.656 1.00 30.43  ? 197 LEU A CD1 1 
ATOM   1318  C CD2 . LEU A 1 176 ? 185.339 188.500 210.079 1.00 30.43  ? 197 LEU A CD2 1 
ATOM   1319  N N   . LEU A 1 177 ? 187.783 184.321 207.723 1.00 25.03  ? 198 LEU A N   1 
ATOM   1320  C CA  . LEU A 1 177 ? 188.378 183.837 206.477 1.00 25.03  ? 198 LEU A CA  1 
ATOM   1321  C C   . LEU A 1 177 ? 187.328 183.240 205.545 1.00 25.03  ? 198 LEU A C   1 
ATOM   1322  O O   . LEU A 1 177 ? 187.384 183.453 204.323 1.00 25.03  ? 198 LEU A O   1 
ATOM   1323  C CB  . LEU A 1 177 ? 189.486 182.824 206.772 1.00 25.03  ? 198 LEU A CB  1 
ATOM   1324  C CG  . LEU A 1 177 ? 190.936 183.321 206.864 1.00 25.03  ? 198 LEU A CG  1 
ATOM   1325  C CD1 . LEU A 1 177 ? 191.375 183.807 205.502 1.00 25.03  ? 198 LEU A CD1 1 
ATOM   1326  C CD2 . LEU A 1 177 ? 191.164 184.420 207.892 1.00 25.03  ? 198 LEU A CD2 1 
ATOM   1327  N N   . GLN A 1 178 ? 186.352 182.510 206.102 1.00 25.92  ? 199 GLN A N   1 
ATOM   1328  C CA  . GLN A 1 178 ? 185.251 181.995 205.289 1.00 25.92  ? 199 GLN A CA  1 
ATOM   1329  C C   . GLN A 1 178 ? 184.412 183.128 204.706 1.00 25.92  ? 199 GLN A C   1 
ATOM   1330  O O   . GLN A 1 178 ? 184.008 183.080 203.534 1.00 25.92  ? 199 GLN A O   1 
ATOM   1331  C CB  . GLN A 1 178 ? 184.384 181.052 206.122 1.00 25.92  ? 199 GLN A CB  1 
ATOM   1332  C CG  . GLN A 1 178 ? 183.428 180.194 205.311 1.00 25.92  ? 199 GLN A CG  1 
ATOM   1333  C CD  . GLN A 1 178 ? 182.041 180.795 205.213 1.00 25.92  ? 199 GLN A CD  1 
ATOM   1334  O OE1 . GLN A 1 178 ? 181.598 181.511 206.110 1.00 25.92  ? 199 GLN A OE1 1 
ATOM   1335  N NE2 . GLN A 1 178 ? 181.345 180.503 204.121 1.00 25.92  ? 199 GLN A NE2 1 
ATOM   1336  N N   . TYR A 1 179 ? 184.181 184.182 205.491 1.00 27.21  ? 200 TYR A N   1 
ATOM   1337  C CA  . TYR A 1 179 ? 183.413 185.306 204.969 1.00 27.21  ? 200 TYR A CA  1 
ATOM   1338  C C   . TYR A 1 179 ? 184.203 186.104 203.936 1.00 27.21  ? 200 TYR A C   1 
ATOM   1339  O O   . TYR A 1 179 ? 183.609 186.605 202.979 1.00 27.21  ? 200 TYR A O   1 
ATOM   1340  C CB  . TYR A 1 179 ? 182.935 186.200 206.111 1.00 27.21  ? 200 TYR A CB  1 
ATOM   1341  C CG  . TYR A 1 179 ? 181.971 187.274 205.664 1.00 27.21  ? 200 TYR A CG  1 
ATOM   1342  C CD1 . TYR A 1 179 ? 180.930 186.972 204.792 1.00 27.21  ? 200 TYR A CD1 1 
ATOM   1343  C CD2 . TYR A 1 179 ? 182.071 188.574 206.144 1.00 27.21  ? 200 TYR A CD2 1 
ATOM   1344  C CE1 . TYR A 1 179 ? 180.035 187.942 204.385 1.00 27.21  ? 200 TYR A CE1 1 
ATOM   1345  C CE2 . TYR A 1 179 ? 181.175 189.551 205.747 1.00 27.21  ? 200 TYR A CE2 1 
ATOM   1346  C CZ  . TYR A 1 179 ? 180.161 189.227 204.866 1.00 27.21  ? 200 TYR A CZ  1 
ATOM   1347  O OH  . TYR A 1 179 ? 179.266 190.190 204.461 1.00 27.21  ? 200 TYR A OH  1 
ATOM   1348  N N   . TYR A 1 180 ? 185.530 186.204 204.089 1.00 26.02  ? 201 TYR A N   1 
ATOM   1349  C CA  . TYR A 1 180 ? 186.355 186.842 203.064 1.00 26.02  ? 201 TYR A CA  1 
ATOM   1350  C C   . TYR A 1 180 ? 186.318 186.052 201.762 1.00 26.02  ? 201 TYR A C   1 
ATOM   1351  O O   . TYR A 1 180 ? 186.300 186.635 200.669 1.00 26.02  ? 201 TYR A O   1 
ATOM   1352  C CB  . TYR A 1 180 ? 187.793 186.993 203.556 1.00 26.02  ? 201 TYR A CB  1 
ATOM   1353  C CG  . TYR A 1 180 ? 188.748 187.476 202.489 1.00 26.02  ? 201 TYR A CG  1 
ATOM   1354  C CD1 . TYR A 1 180 ? 188.701 188.788 202.038 1.00 26.02  ? 201 TYR A CD1 1 
ATOM   1355  C CD2 . TYR A 1 180 ? 189.697 186.623 201.936 1.00 26.02  ? 201 TYR A CD2 1 
ATOM   1356  C CE1 . TYR A 1 180 ? 189.567 189.238 201.061 1.00 26.02  ? 201 TYR A CE1 1 
ATOM   1357  C CE2 . TYR A 1 180 ? 190.566 187.064 200.959 1.00 26.02  ? 201 TYR A CE2 1 
ATOM   1358  C CZ  . TYR A 1 180 ? 190.497 188.372 200.527 1.00 26.02  ? 201 TYR A CZ  1 
ATOM   1359  O OH  . TYR A 1 180 ? 191.364 188.811 199.555 1.00 26.02  ? 201 TYR A OH  1 
ATOM   1360  N N   . SER A 1 181 ? 186.268 184.720 201.864 1.00 21.28  ? 202 SER A N   1 
ATOM   1361  C CA  . SER A 1 181 ? 186.021 183.905 200.679 1.00 21.28  ? 202 SER A CA  1 
ATOM   1362  C C   . SER A 1 181 ? 184.623 184.133 200.109 1.00 21.28  ? 202 SER A C   1 
ATOM   1363  O O   . SER A 1 181 ? 184.407 183.931 198.909 1.00 21.28  ? 202 SER A O   1 
ATOM   1364  C CB  . SER A 1 181 ? 186.219 182.428 201.006 1.00 21.28  ? 202 SER A CB  1 
ATOM   1365  O OG  . SER A 1 181 ? 185.741 181.614 199.952 1.00 21.28  ? 202 SER A OG  1 
ATOM   1366  N N   . GLN A 1 182 ? 183.660 184.535 200.946 1.00 49.69  ? 203 GLN A N   1 
ATOM   1367  C CA  . GLN A 1 182 ? 182.325 184.841 200.425 1.00 49.69  ? 203 GLN A CA  1 
ATOM   1368  C C   . GLN A 1 182 ? 182.273 186.186 199.694 1.00 49.69  ? 203 GLN A C   1 
ATOM   1369  O O   . GLN A 1 182 ? 181.539 186.319 198.707 1.00 49.69  ? 203 GLN A O   1 
ATOM   1370  C CB  . GLN A 1 182 ? 181.287 184.794 201.544 1.00 49.69  ? 203 GLN A CB  1 
ATOM   1371  C CG  . GLN A 1 182 ? 181.050 183.401 202.087 1.00 49.69  ? 203 GLN A CG  1 
ATOM   1372  C CD  . GLN A 1 182 ? 179.909 182.695 201.385 1.00 49.69  ? 203 GLN A CD  1 
ATOM   1373  O OE1 . GLN A 1 182 ? 179.922 182.527 200.166 1.00 49.69  ? 203 GLN A OE1 1 
ATOM   1374  N NE2 . GLN A 1 182 ? 178.914 182.272 202.155 1.00 49.69  ? 203 GLN A NE2 1 
ATOM   1375  N N   . ILE A 1 183 ? 182.996 187.208 200.180 1.00 20.01  ? 204 ILE A N   1 
ATOM   1376  C CA  . ILE A 1 183 ? 183.149 188.437 199.382 1.00 20.01  ? 204 ILE A CA  1 
ATOM   1377  C C   . ILE A 1 183 ? 183.899 188.163 198.082 1.00 20.01  ? 204 ILE A C   1 
ATOM   1378  O O   . ILE A 1 183 ? 183.479 188.616 197.009 1.00 20.01  ? 204 ILE A O   1 
ATOM   1379  C CB  . ILE A 1 183 ? 183.782 189.611 200.177 1.00 20.01  ? 204 ILE A CB  1 
ATOM   1380  C CG1 . ILE A 1 183 ? 182.845 190.201 201.243 1.00 20.01  ? 204 ILE A CG1 1 
ATOM   1381  C CG2 . ILE A 1 183 ? 184.281 190.740 199.276 1.00 20.01  ? 204 ILE A CG2 1 
ATOM   1382  C CD1 . ILE A 1 183 ? 182.908 189.663 202.592 1.00 20.01  ? 204 ILE A CD1 1 
ATOM   1383  N N   . LEU A 1 184 ? 184.965 187.352 198.129 1.00 19.17  ? 205 LEU A N   1 
ATOM   1384  C CA  . LEU A 1 184 ? 185.733 187.138 196.884 1.00 19.17  ? 205 LEU A CA  1 
ATOM   1385  C C   . LEU A 1 184 ? 185.008 186.252 195.811 1.00 19.17  ? 205 LEU A C   1 
ATOM   1386  O O   . LEU A 1 184 ? 185.671 185.885 194.832 1.00 19.17  ? 205 LEU A O   1 
ATOM   1387  C CB  . LEU A 1 184 ? 187.100 186.532 197.199 1.00 19.17  ? 205 LEU A CB  1 
ATOM   1388  C CG  . LEU A 1 184 ? 188.266 187.521 197.252 1.00 19.17  ? 205 LEU A CG  1 
ATOM   1389  C CD1 . LEU A 1 184 ? 189.574 186.779 197.451 1.00 19.17  ? 205 LEU A CD1 1 
ATOM   1390  C CD2 . LEU A 1 184 ? 188.316 188.371 195.990 1.00 19.17  ? 205 LEU A CD2 1 
ATOM   1391  N N   . THR A 1 185 ? 183.728 185.908 195.950 1.00 29.15  ? 206 THR A N   1 
ATOM   1392  C CA  . THR A 1 185 ? 182.956 185.244 194.909 1.00 29.15  ? 206 THR A CA  1 
ATOM   1393  C C   . THR A 1 185 ? 181.929 186.167 194.268 1.00 29.15  ? 206 THR A C   1 
ATOM   1394  O O   . THR A 1 185 ? 181.842 186.232 193.037 1.00 29.15  ? 206 THR A O   1 
ATOM   1395  C CB  . THR A 1 185 ? 182.258 184.003 195.490 1.00 29.15  ? 206 THR A CB  1 
ATOM   1396  O OG1 . THR A 1 185 ? 183.241 183.120 196.043 1.00 29.15  ? 206 THR A OG1 1 
ATOM   1397  C CG2 . THR A 1 185 ? 181.480 183.262 194.414 1.00 29.15  ? 206 THR A CG2 1 
ATOM   1398  N N   . VAL A 1 186 ? 181.151 186.895 195.077 1.00 19.00  ? 207 VAL A N   1 
ATOM   1399  C CA  . VAL A 1 186 ? 180.103 187.760 194.536 1.00 19.00  ? 207 VAL A CA  1 
ATOM   1400  C C   . VAL A 1 186 ? 180.696 188.987 193.838 1.00 19.00  ? 207 VAL A C   1 
ATOM   1401  O O   . VAL A 1 186 ? 180.274 189.344 192.731 1.00 19.00  ? 207 VAL A O   1 
ATOM   1402  C CB  . VAL A 1 186 ? 179.081 188.118 195.640 1.00 19.00  ? 207 VAL A CB  1 
ATOM   1403  C CG1 . VAL A 1 186 ? 179.745 188.672 196.900 1.00 19.00  ? 207 VAL A CG1 1 
ATOM   1404  C CG2 . VAL A 1 186 ? 178.052 189.112 195.117 1.00 19.00  ? 207 VAL A CG2 1 
ATOM   1405  N N   . PHE A 1 187 ? 181.698 189.624 194.433 1.00 21.64  ? 208 PHE A N   1 
ATOM   1406  C CA  . PHE A 1 187 ? 182.380 190.748 193.788 1.00 21.64  ? 208 PHE A CA  1 
ATOM   1407  C C   . PHE A 1 187 ? 183.607 190.273 193.020 1.00 21.64  ? 208 PHE A C   1 
ATOM   1408  O O   . PHE A 1 187 ? 184.710 190.790 193.189 1.00 21.64  ? 208 PHE A O   1 
ATOM   1409  C CB  . PHE A 1 187 ? 182.752 191.805 194.822 1.00 21.64  ? 208 PHE A CB  1 
ATOM   1410  C CG  . PHE A 1 187 ? 181.573 192.369 195.566 1.00 21.64  ? 208 PHE A CG  1 
ATOM   1411  C CD1 . PHE A 1 187 ? 180.726 193.282 194.958 1.00 21.64  ? 208 PHE A CD1 1 
ATOM   1412  C CD2 . PHE A 1 187 ? 181.316 191.990 196.874 1.00 21.64  ? 208 PHE A CD2 1 
ATOM   1413  C CE1 . PHE A 1 187 ? 179.640 193.805 195.641 1.00 21.64  ? 208 PHE A CE1 1 
ATOM   1414  C CE2 . PHE A 1 187 ? 180.231 192.509 197.563 1.00 21.64  ? 208 PHE A CE2 1 
ATOM   1415  C CZ  . PHE A 1 187 ? 179.394 193.418 196.944 1.00 21.64  ? 208 PHE A CZ  1 
ATOM   1416  N N   . GLY A 1 188 ? 183.420 189.272 192.165 1.00 30.19  ? 209 GLY A N   1 
ATOM   1417  C CA  . GLY A 1 188 ? 184.492 188.730 191.363 1.00 30.19  ? 209 GLY A CA  1 
ATOM   1418  C C   . GLY A 1 188 ? 184.670 189.437 190.034 1.00 30.19  ? 209 GLY A C   1 
ATOM   1419  O O   . GLY A 1 188 ? 185.725 190.017 189.759 1.00 30.19  ? 209 GLY A O   1 
ATOM   1420  N N   . PRO A 1 189 ? 183.643 189.401 189.173 1.00 34.72  ? 210 PRO A N   1 
ATOM   1421  C CA  . PRO A 1 189 ? 183.693 190.209 187.942 1.00 34.72  ? 210 PRO A CA  1 
ATOM   1422  C C   . PRO A 1 189 ? 183.626 191.707 188.181 1.00 34.72  ? 210 PRO A C   1 
ATOM   1423  O O   . PRO A 1 189 ? 183.958 192.476 187.271 1.00 34.72  ? 210 PRO A O   1 
ATOM   1424  C CB  . PRO A 1 189 ? 182.469 189.721 187.157 1.00 34.72  ? 210 PRO A CB  1 
ATOM   1425  C CG  . PRO A 1 189 ? 182.280 188.325 187.622 1.00 34.72  ? 210 PRO A CG  1 
ATOM   1426  C CD  . PRO A 1 189 ? 182.591 188.370 189.090 1.00 34.72  ? 210 PRO A CD  1 
ATOM   1427  N N   . ASN A 1 190 ? 183.205 192.145 189.368 1.00 32.14  ? 211 ASN A N   1 
ATOM   1428  C CA  . ASN A 1 190 ? 183.072 193.566 189.649 1.00 32.14  ? 211 ASN A CA  1 
ATOM   1429  C C   . ASN A 1 190 ? 184.418 194.255 189.841 1.00 32.14  ? 211 ASN A C   1 
ATOM   1430  O O   . ASN A 1 190 ? 184.487 195.483 189.748 1.00 32.14  ? 211 ASN A O   1 
ATOM   1431  C CB  . ASN A 1 190 ? 182.203 193.762 190.889 1.00 32.14  ? 211 ASN A CB  1 
ATOM   1432  C CG  . ASN A 1 190 ? 181.292 194.959 190.778 1.00 32.14  ? 211 ASN A CG  1 
ATOM   1433  O OD1 . ASN A 1 190 ? 181.704 196.030 190.353 1.00 32.14  ? 211 ASN A OD1 1 
ATOM   1434  N ND2 . ASN A 1 190 ? 180.040 194.778 191.153 1.00 32.14  ? 211 ASN A ND2 1 
ATOM   1435  N N   . LEU A 1 191 ? 185.489 193.501 190.096 1.00 36.75  ? 212 LEU A N   1 
ATOM   1436  C CA  . LEU A 1 191 ? 186.794 194.116 190.310 1.00 36.75  ? 212 LEU A CA  1 
ATOM   1437  C C   . LEU A 1 191 ? 187.429 194.616 189.018 1.00 36.75  ? 212 LEU A C   1 
ATOM   1438  O O   . LEU A 1 191 ? 188.371 195.413 189.078 1.00 36.75  ? 212 LEU A O   1 
ATOM   1439  C CB  . LEU A 1 191 ? 187.737 193.128 190.995 1.00 36.75  ? 212 LEU A CB  1 
ATOM   1440  C CG  . LEU A 1 191 ? 187.373 192.682 192.410 1.00 36.75  ? 212 LEU A CG  1 
ATOM   1441  C CD1 . LEU A 1 191 ? 188.013 191.340 192.725 1.00 36.75  ? 212 LEU A CD1 1 
ATOM   1442  C CD2 . LEU A 1 191 ? 187.795 193.730 193.424 1.00 36.75  ? 212 LEU A CD2 1 
ATOM   1443  N N   . ARG A 1 192 ? 186.945 194.159 187.860 1.00 41.70  ? 213 ARG A N   1 
ATOM   1444  C CA  . ARG A 1 192 ? 187.521 194.574 186.583 1.00 41.70  ? 213 ARG A CA  1 
ATOM   1445  C C   . ARG A 1 192 ? 187.206 196.034 186.276 1.00 41.70  ? 213 ARG A C   1 
ATOM   1446  O O   . ARG A 1 192 ? 188.100 196.812 185.922 1.00 41.70  ? 213 ARG A O   1 
ATOM   1447  C CB  . ARG A 1 192 ? 187.003 193.667 185.468 1.00 41.70  ? 213 ARG A CB  1 
ATOM   1448  C CG  . ARG A 1 192 ? 187.387 194.110 184.066 1.00 41.70  ? 213 ARG A CG  1 
ATOM   1449  C CD  . ARG A 1 192 ? 187.150 193.030 183.005 1.00 41.70  ? 213 ARG A CD  1 
ATOM   1450  N NE  . ARG A 1 192 ? 185.754 192.616 182.883 1.00 41.70  ? 213 ARG A NE  1 
ATOM   1451  C CZ  . ARG A 1 192 ? 185.242 191.510 183.409 1.00 41.70  ? 213 ARG A CZ  1 
ATOM   1452  N NH1 . ARG A 1 192 ? 185.986 190.668 184.107 1.00 41.70  ? 213 ARG A NH1 1 
ATOM   1453  N NH2 . ARG A 1 192 ? 183.951 191.245 183.231 1.00 41.70  ? 213 ARG A NH2 1 
ATOM   1454  N N   . ASP A 1 193 ? 185.942 196.425 186.410 1.00 43.81  ? 214 ASP A N   1 
ATOM   1455  C CA  . ASP A 1 193 ? 185.519 197.806 186.175 1.00 43.81  ? 214 ASP A CA  1 
ATOM   1456  C C   . ASP A 1 193 ? 184.306 198.058 187.057 1.00 43.81  ? 214 ASP A C   1 
ATOM   1457  O O   . ASP A 1 193 ? 183.163 197.797 186.651 1.00 43.81  ? 214 ASP A O   1 
ATOM   1458  C CB  . ASP A 1 193 ? 185.196 198.066 184.707 1.00 43.81  ? 214 ASP A CB  1 
ATOM   1459  C CG  . ASP A 1 193 ? 184.870 199.520 184.432 1.00 43.81  ? 214 ASP A CG  1 
ATOM   1460  O OD1 . ASP A 1 193 ? 185.335 200.391 185.197 1.00 43.81  ? 214 ASP A OD1 1 
ATOM   1461  O OD2 . ASP A 1 193 ? 184.147 199.794 183.452 1.00 43.81  ? 214 ASP A OD2 1 
ATOM   1462  N N   . PRO A 1 194 ? 184.509 198.574 188.272 1.00 36.37  ? 215 PRO A N   1 
ATOM   1463  C CA  . PRO A 1 194 ? 183.415 198.609 189.253 1.00 36.37  ? 215 PRO A CA  1 
ATOM   1464  C C   . PRO A 1 194 ? 182.470 199.793 189.141 1.00 36.37  ? 215 PRO A C   1 
ATOM   1465  O O   . PRO A 1 194 ? 182.074 200.362 190.161 1.00 36.37  ? 215 PRO A O   1 
ATOM   1466  C CB  . PRO A 1 194 ? 184.165 198.647 190.587 1.00 36.37  ? 215 PRO A CB  1 
ATOM   1467  C CG  . PRO A 1 194 ? 185.410 199.380 190.264 1.00 36.37  ? 215 PRO A CG  1 
ATOM   1468  C CD  . PRO A 1 194 ? 185.795 198.964 188.873 1.00 36.37  ? 215 PRO A CD  1 
ATOM   1469  N N   . ALA A 1 195 ? 182.084 200.161 187.925 1.00 31.03  ? 216 ALA A N   1 
ATOM   1470  C CA  . ALA A 1 195 ? 181.031 201.152 187.734 1.00 31.03  ? 216 ALA A CA  1 
ATOM   1471  C C   . ALA A 1 195 ? 179.996 200.746 186.703 1.00 31.03  ? 216 ALA A C   1 
ATOM   1472  O O   . ALA A 1 195 ? 178.881 201.276 186.739 1.00 31.03  ? 216 ALA A O   1 
ATOM   1473  C CB  . ALA A 1 195 ? 181.628 202.505 187.330 1.00 31.03  ? 216 ALA A CB  1 
ATOM   1474  N N   . THR A 1 196 ? 180.315 199.831 185.788 1.00 40.86  ? 217 THR A N   1 
ATOM   1475  C CA  . THR A 1 196 ? 179.422 199.433 184.711 1.00 40.86  ? 217 THR A CA  1 
ATOM   1476  C C   . THR A 1 196 ? 178.935 197.998 184.843 1.00 40.86  ? 217 THR A C   1 
ATOM   1477  O O   . THR A 1 196 ? 178.159 197.542 183.997 1.00 40.86  ? 217 THR A O   1 
ATOM   1478  C CB  . THR A 1 196 ? 180.123 199.607 183.359 1.00 40.86  ? 217 THR A CB  1 
ATOM   1479  O OG1 . THR A 1 196 ? 181.105 198.577 183.198 1.00 40.86  ? 217 THR A OG1 1 
ATOM   1480  C CG2 . THR A 1 196 ? 180.822 200.955 183.295 1.00 40.86  ? 217 THR A CG2 1 
ATOM   1481  N N   . VAL A 1 197 ? 179.368 197.276 185.868 1.00 34.42  ? 218 VAL A N   1 
ATOM   1482  C CA  . VAL A 1 197 ? 179.032 195.869 186.060 1.00 34.42  ? 218 VAL A CA  1 
ATOM   1483  C C   . VAL A 1 197 ? 177.999 195.779 187.178 1.00 34.42  ? 218 VAL A C   1 
ATOM   1484  O O   . VAL A 1 197 ? 178.271 196.226 188.299 1.00 34.42  ? 218 VAL A O   1 
ATOM   1485  C CB  . VAL A 1 197 ? 180.276 195.029 186.388 1.00 34.42  ? 218 VAL A CB  1 
ATOM   1486  C CG1 . VAL A 1 197 ? 179.881 193.589 186.665 1.00 34.42  ? 218 VAL A CG1 1 
ATOM   1487  C CG2 . VAL A 1 197 ? 181.277 195.100 185.247 1.00 34.42  ? 218 VAL A CG2 1 
ATOM   1488  N N   . PRO A 1 198 ? 176.819 195.224 186.928 1.00 26.53  ? 219 PRO A N   1 
ATOM   1489  C CA  . PRO A 1 198 ? 175.786 195.165 187.964 1.00 26.53  ? 219 PRO A CA  1 
ATOM   1490  C C   . PRO A 1 198 ? 175.997 193.990 188.914 1.00 26.53  ? 219 PRO A C   1 
ATOM   1491  O O   . PRO A 1 198 ? 176.830 193.111 188.696 1.00 26.53  ? 219 PRO A O   1 
ATOM   1492  C CB  . PRO A 1 198 ? 174.499 194.998 187.155 1.00 26.53  ? 219 PRO A CB  1 
ATOM   1493  C CG  . PRO A 1 198 ? 174.932 194.222 185.960 1.00 26.53  ? 219 PRO A CG  1 
ATOM   1494  C CD  . PRO A 1 198 ? 176.349 194.653 185.652 1.00 26.53  ? 219 PRO A CD  1 
ATOM   1495  N N   . VAL A 1 199 ? 175.209 193.997 189.987 1.00 24.02  ? 220 VAL A N   1 
ATOM   1496  C CA  . VAL A 1 199 ? 175.216 192.944 190.998 1.00 24.02  ? 220 VAL A CA  1 
ATOM   1497  C C   . VAL A 1 199 ? 173.824 192.335 191.044 1.00 24.02  ? 220 VAL A C   1 
ATOM   1498  O O   . VAL A 1 199 ? 172.845 193.039 191.319 1.00 24.02  ? 220 VAL A O   1 
ATOM   1499  C CB  . VAL A 1 199 ? 175.615 193.481 192.382 1.00 24.02  ? 220 VAL A CB  1 
ATOM   1500  C CG1 . VAL A 1 199 ? 175.339 192.444 193.460 1.00 24.02  ? 220 VAL A CG1 1 
ATOM   1501  C CG2 . VAL A 1 199 ? 177.065 193.873 192.400 1.00 24.02  ? 220 VAL A CG2 1 
ATOM   1502  N N   . SER A 1 200 ? 173.733 191.036 190.775 1.00 22.59  ? 221 SER A N   1 
ATOM   1503  C CA  . SER A 1 200 ? 172.466 190.335 190.920 1.00 22.59  ? 221 SER A CA  1 
ATOM   1504  C C   . SER A 1 200 ? 172.113 190.189 192.396 1.00 22.59  ? 221 SER A C   1 
ATOM   1505  O O   . SER A 1 200 ? 172.985 190.022 193.252 1.00 22.59  ? 221 SER A O   1 
ATOM   1506  C CB  . SER A 1 200 ? 172.532 188.962 190.255 1.00 22.59  ? 221 SER A CB  1 
ATOM   1507  O OG  . SER A 1 200 ? 172.730 189.083 188.858 1.00 22.59  ? 221 SER A OG  1 
ATOM   1508  N N   . ILE A 1 201 ? 170.813 190.260 192.690 1.00 21.05  ? 222 ILE A N   1 
ATOM   1509  C CA  . ILE A 1 201 ? 170.370 190.232 194.080 1.00 21.05  ? 222 ILE A CA  1 
ATOM   1510  C C   . ILE A 1 201 ? 170.468 188.831 194.685 1.00 21.05  ? 222 ILE A C   1 
ATOM   1511  O O   . ILE A 1 201 ? 170.548 188.702 195.913 1.00 21.05  ? 222 ILE A O   1 
ATOM   1512  C CB  . ILE A 1 201 ? 168.949 190.822 194.184 1.00 21.05  ? 222 ILE A CB  1 
ATOM   1513  C CG1 . ILE A 1 201 ? 168.658 191.330 195.599 1.00 21.05  ? 222 ILE A CG1 1 
ATOM   1514  C CG2 . ILE A 1 201 ? 167.898 189.824 193.748 1.00 21.05  ? 222 ILE A CG2 1 
ATOM   1515  C CD1 . ILE A 1 201 ? 169.439 192.563 195.974 1.00 21.05  ? 222 ILE A CD1 1 
ATOM   1516  N N   . GLN A 1 202 ? 170.514 187.778 193.863 1.00 23.79  ? 223 GLN A N   1 
ATOM   1517  C CA  . GLN A 1 202 ? 170.730 186.436 194.397 1.00 23.79  ? 223 GLN A CA  1 
ATOM   1518  C C   . GLN A 1 202 ? 172.173 186.257 194.854 1.00 23.79  ? 223 GLN A C   1 
ATOM   1519  O O   . GLN A 1 202 ? 172.428 185.723 195.942 1.00 23.79  ? 223 GLN A O   1 
ATOM   1520  C CB  . GLN A 1 202 ? 170.358 185.389 193.346 1.00 23.79  ? 223 GLN A CB  1 
ATOM   1521  C CG  . GLN A 1 202 ? 170.611 183.951 193.770 1.00 23.79  ? 223 GLN A CG  1 
ATOM   1522  C CD  . GLN A 1 202 ? 169.919 183.594 195.071 1.00 23.79  ? 223 GLN A CD  1 
ATOM   1523  O OE1 . GLN A 1 202 ? 170.566 183.413 196.102 1.00 23.79  ? 223 GLN A OE1 1 
ATOM   1524  N NE2 . GLN A 1 202 ? 168.596 183.488 195.028 1.00 23.79  ? 223 GLN A NE2 1 
ATOM   1525  N N   . ALA A 1 203 ? 173.128 186.724 194.043 1.00 23.02  ? 224 ALA A N   1 
ATOM   1526  C CA  . ALA A 1 203 ? 174.533 186.681 194.431 1.00 23.02  ? 224 ALA A CA  1 
ATOM   1527  C C   . ALA A 1 203 ? 174.817 187.597 195.613 1.00 23.02  ? 224 ALA A C   1 
ATOM   1528  O O   . ALA A 1 203 ? 175.665 187.275 196.452 1.00 23.02  ? 224 ALA A O   1 
ATOM   1529  C CB  . ALA A 1 203 ? 175.417 187.057 193.243 1.00 23.02  ? 224 ALA A CB  1 
ATOM   1530  N N   . LEU A 1 204 ? 174.116 188.729 195.701 1.00 18.04  ? 225 LEU A N   1 
ATOM   1531  C CA  . LEU A 1 204 ? 174.267 189.605 196.857 1.00 18.04  ? 225 LEU A CA  1 
ATOM   1532  C C   . LEU A 1 204 ? 173.653 188.980 198.106 1.00 18.04  ? 225 LEU A C   1 
ATOM   1533  O O   . LEU A 1 204 ? 174.194 189.121 199.209 1.00 18.04  ? 225 LEU A O   1 
ATOM   1534  C CB  . LEU A 1 204 ? 173.643 190.968 196.558 1.00 18.04  ? 225 LEU A CB  1 
ATOM   1535  C CG  . LEU A 1 204 ? 173.666 192.002 197.681 1.00 18.04  ? 225 LEU A CG  1 
ATOM   1536  C CD1 . LEU A 1 204 ? 175.100 192.278 198.070 1.00 18.04  ? 225 LEU A CD1 1 
ATOM   1537  C CD2 . LEU A 1 204 ? 172.971 193.279 197.250 1.00 18.04  ? 225 LEU A CD2 1 
ATOM   1538  N N   . SER A 1 205 ? 172.540 188.259 197.950 1.00 18.21  ? 226 SER A N   1 
ATOM   1539  C CA  . SER A 1 205 ? 171.924 187.561 199.072 1.00 18.21  ? 226 SER A CA  1 
ATOM   1540  C C   . SER A 1 205 ? 172.687 186.307 199.476 1.00 18.21  ? 226 SER A C   1 
ATOM   1541  O O   . SER A 1 205 ? 172.424 185.767 200.555 1.00 18.21  ? 226 SER A O   1 
ATOM   1542  C CB  . SER A 1 205 ? 170.480 187.195 198.733 1.00 18.21  ? 226 SER A CB  1 
ATOM   1543  O OG  . SER A 1 205 ? 170.434 186.179 197.748 1.00 18.21  ? 226 SER A OG  1 
ATOM   1544  N N   . GLN A 1 206 ? 173.612 185.831 198.635 1.00 20.26  ? 227 GLN A N   1 
ATOM   1545  C CA  . GLN A 1 206 ? 174.487 184.721 199.016 1.00 20.26  ? 227 GLN A CA  1 
ATOM   1546  C C   . GLN A 1 206 ? 175.430 185.062 200.167 1.00 20.26  ? 227 GLN A C   1 
ATOM   1547  O O   . GLN A 1 206 ? 175.979 184.145 200.787 1.00 20.26  ? 227 GLN A O   1 
ATOM   1548  C CB  . GLN A 1 206 ? 175.314 184.255 197.816 1.00 20.26  ? 227 GLN A CB  1 
ATOM   1549  C CG  . GLN A 1 206 ? 174.569 183.354 196.854 1.00 20.26  ? 227 GLN A CG  1 
ATOM   1550  C CD  . GLN A 1 206 ? 174.248 182.005 197.461 1.00 20.26  ? 227 GLN A CD  1 
ATOM   1551  O OE1 . GLN A 1 206 ? 175.047 181.443 198.209 1.00 20.26  ? 227 GLN A OE1 1 
ATOM   1552  N NE2 . GLN A 1 206 ? 173.073 181.477 197.141 1.00 20.26  ? 227 GLN A NE2 1 
ATOM   1553  N N   . LEU A 1 207 ? 175.646 186.349 200.461 1.00 14.55  ? 228 LEU A N   1 
ATOM   1554  C CA  . LEU A 1 207 ? 176.444 186.724 201.624 1.00 14.55  ? 228 LEU A CA  1 
ATOM   1555  C C   . LEU A 1 207 ? 175.729 186.404 202.932 1.00 14.55  ? 228 LEU A C   1 
ATOM   1556  O O   . LEU A 1 207 ? 176.385 186.179 203.955 1.00 14.55  ? 228 LEU A O   1 
ATOM   1557  C CB  . LEU A 1 207 ? 176.788 188.212 201.573 1.00 14.55  ? 228 LEU A CB  1 
ATOM   1558  C CG  . LEU A 1 207 ? 177.819 188.685 200.548 1.00 14.55  ? 228 LEU A CG  1 
ATOM   1559  C CD1 . LEU A 1 207 ? 178.180 190.139 200.800 1.00 14.55  ? 228 LEU A CD1 1 
ATOM   1560  C CD2 . LEU A 1 207 ? 179.059 187.811 200.585 1.00 14.55  ? 228 LEU A CD2 1 
ATOM   1561  N N   . PHE A 1 208 ? 174.398 186.378 202.921 1.00 24.49  ? 229 PHE A N   1 
ATOM   1562  C CA  . PHE A 1 208 ? 173.590 186.172 204.123 1.00 24.49  ? 229 PHE A CA  1 
ATOM   1563  C C   . PHE A 1 208 ? 173.015 184.764 204.186 1.00 24.49  ? 229 PHE A C   1 
ATOM   1564  O O   . PHE A 1 208 ? 171.864 184.584 204.602 1.00 24.49  ? 229 PHE A O   1 
ATOM   1565  C CB  . PHE A 1 208 ? 172.475 187.211 204.190 1.00 24.49  ? 229 PHE A CB  1 
ATOM   1566  C CG  . PHE A 1 208 ? 172.876 188.558 203.669 1.00 24.49  ? 229 PHE A CG  1 
ATOM   1567  C CD1 . PHE A 1 208 ? 173.855 189.299 204.308 1.00 24.49  ? 229 PHE A CD1 1 
ATOM   1568  C CD2 . PHE A 1 208 ? 172.286 189.076 202.529 1.00 24.49  ? 229 PHE A CD2 1 
ATOM   1569  C CE1 . PHE A 1 208 ? 174.233 190.536 203.829 1.00 24.49  ? 229 PHE A CE1 1 
ATOM   1570  C CE2 . PHE A 1 208 ? 172.660 190.313 202.044 1.00 24.49  ? 229 PHE A CE2 1 
ATOM   1571  C CZ  . PHE A 1 208 ? 173.636 191.040 202.693 1.00 24.49  ? 229 PHE A CZ  1 
ATOM   1572  N N   . GLU A 1 209 ? 173.816 183.772 203.768 1.00 26.73  ? 230 GLU A N   1 
ATOM   1573  C CA  . GLU A 1 209 ? 173.443 182.351 203.693 1.00 26.73  ? 230 GLU A CA  1 
ATOM   1574  C C   . GLU A 1 209 ? 172.213 182.126 202.814 1.00 26.73  ? 230 GLU A C   1 
ATOM   1575  O O   . GLU A 1 209 ? 171.350 181.302 203.123 1.00 26.73  ? 230 GLU A O   1 
ATOM   1576  C CB  . GLU A 1 209 ? 173.241 181.734 205.083 1.00 26.73  ? 230 GLU A CB  1 
ATOM   1577  C CG  . GLU A 1 209 ? 174.525 181.512 205.864 1.00 26.73  ? 230 GLU A CG  1 
ATOM   1578  C CD  . GLU A 1 209 ? 174.861 182.670 206.781 1.00 26.73  ? 230 GLU A CD  1 
ATOM   1579  O OE1 . GLU A 1 209 ? 174.017 183.578 206.930 1.00 26.73  ? 230 GLU A OE1 1 
ATOM   1580  O OE2 . GLU A 1 209 ? 175.971 182.672 207.356 1.00 26.73  ? 230 GLU A OE2 1 
ATOM   1581  N N   . GLY A 1 210 ? 172.143 182.855 201.702 1.00 22.79  ? 231 GLY A N   1 
ATOM   1582  C CA  . GLY A 1 210 ? 171.069 182.694 200.740 1.00 22.79  ? 231 GLY A CA  1 
ATOM   1583  C C   . GLY A 1 210 ? 169.705 183.141 201.223 1.00 22.79  ? 231 GLY A C   1 
ATOM   1584  O O   . GLY A 1 210 ? 168.718 182.419 201.059 1.00 22.79  ? 231 GLY A O   1 
ATOM   1585  N N   . ASN A 1 211 ? 169.632 184.329 201.817 1.00 20.73  ? 232 ASN A N   1 
ATOM   1586  C CA  . ASN A 1 211 ? 168.386 184.872 202.354 1.00 20.73  ? 232 ASN A CA  1 
ATOM   1587  C C   . ASN A 1 211 ? 167.952 186.026 201.455 1.00 20.73  ? 232 ASN A C   1 
ATOM   1588  O O   . ASN A 1 211 ? 168.282 187.186 201.711 1.00 20.73  ? 232 ASN A O   1 
ATOM   1589  C CB  . ASN A 1 211 ? 168.568 185.321 203.801 1.00 20.73  ? 232 ASN A CB  1 
ATOM   1590  C CG  . ASN A 1 211 ? 167.260 185.383 204.560 1.00 20.73  ? 232 ASN A CG  1 
ATOM   1591  O OD1 . ASN A 1 211 ? 166.185 185.245 203.979 1.00 20.73  ? 232 ASN A OD1 1 
ATOM   1592  N ND2 . ASN A 1 211 ? 167.345 185.593 205.868 1.00 20.73  ? 232 ASN A ND2 1 
ATOM   1593  N N   . LEU A 1 212 ? 167.206 185.703 200.398 1.00 20.06  ? 233 LEU A N   1 
ATOM   1594  C CA  . LEU A 1 212 ? 166.726 186.728 199.477 1.00 20.06  ? 233 LEU A CA  1 
ATOM   1595  C C   . LEU A 1 212 ? 165.542 187.498 200.048 1.00 20.06  ? 233 LEU A C   1 
ATOM   1596  O O   . LEU A 1 212 ? 165.383 188.690 199.749 1.00 20.06  ? 233 LEU A O   1 
ATOM   1597  C CB  . LEU A 1 212 ? 166.353 186.087 198.137 1.00 20.06  ? 233 LEU A CB  1 
ATOM   1598  C CG  . LEU A 1 212 ? 166.108 186.963 196.904 1.00 20.06  ? 233 LEU A CG  1 
ATOM   1599  C CD1 . LEU A 1 212 ? 166.664 186.268 195.678 1.00 20.06  ? 233 LEU A CD1 1 
ATOM   1600  C CD2 . LEU A 1 212 ? 164.627 187.252 196.693 1.00 20.06  ? 233 LEU A CD2 1 
ATOM   1601  N N   . GLU A 1 213 ? 164.705 186.839 200.855 1.00 22.40  ? 234 GLU A N   1 
ATOM   1602  C CA  . GLU A 1 213 ? 163.511 187.491 201.380 1.00 22.40  ? 234 GLU A CA  1 
ATOM   1603  C C   . GLU A 1 213 ? 163.853 188.544 202.424 1.00 22.40  ? 234 GLU A C   1 
ATOM   1604  O O   . GLU A 1 213 ? 163.101 189.511 202.582 1.00 22.40  ? 234 GLU A O   1 
ATOM   1605  C CB  . GLU A 1 213 ? 162.553 186.453 201.963 1.00 22.40  ? 234 GLU A CB  1 
ATOM   1606  C CG  . GLU A 1 213 ? 161.089 186.875 201.943 1.00 22.40  ? 234 GLU A CG  1 
ATOM   1607  C CD  . GLU A 1 213 ? 160.530 187.038 200.542 1.00 22.40  ? 234 GLU A CD  1 
ATOM   1608  O OE1 . GLU A 1 213 ? 160.949 186.288 199.634 1.00 22.40  ? 234 GLU A OE1 1 
ATOM   1609  O OE2 . GLU A 1 213 ? 159.664 187.917 200.349 1.00 22.40  ? 234 GLU A OE2 1 
ATOM   1610  N N   . LEU A 1 214 ? 164.983 188.389 203.121 1.00 16.26  ? 235 LEU A N   1 
ATOM   1611  C CA  . LEU A 1 214 ? 165.446 189.425 204.042 1.00 16.26  ? 235 LEU A CA  1 
ATOM   1612  C C   . LEU A 1 214 ? 165.809 190.706 203.300 1.00 16.26  ? 235 LEU A C   1 
ATOM   1613  O O   . LEU A 1 214 ? 165.404 191.801 203.710 1.00 16.26  ? 235 LEU A O   1 
ATOM   1614  C CB  . LEU A 1 214 ? 166.645 188.915 204.840 1.00 16.26  ? 235 LEU A CB  1 
ATOM   1615  C CG  . LEU A 1 214 ? 167.229 189.859 205.891 1.00 16.26  ? 235 LEU A CG  1 
ATOM   1616  C CD1 . LEU A 1 214 ? 166.159 190.302 206.873 1.00 16.26  ? 235 LEU A CD1 1 
ATOM   1617  C CD2 . LEU A 1 214 ? 168.386 189.194 206.618 1.00 16.26  ? 235 LEU A CD2 1 
ATOM   1618  N N   . LEU A 1 215 ? 166.546 190.580 202.191 1.00 16.43  ? 236 LEU A N   1 
ATOM   1619  C CA  . LEU A 1 215 ? 166.896 191.738 201.373 1.00 16.43  ? 236 LEU A CA  1 
ATOM   1620  C C   . LEU A 1 215 ? 165.666 192.352 200.718 1.00 16.43  ? 236 LEU A C   1 
ATOM   1621  O O   . LEU A 1 215 ? 165.561 193.579 200.614 1.00 16.43  ? 236 LEU A O   1 
ATOM   1622  C CB  . LEU A 1 215 ? 167.910 191.337 200.304 1.00 16.43  ? 236 LEU A CB  1 
ATOM   1623  C CG  . LEU A 1 215 ? 169.395 191.382 200.652 1.00 16.43  ? 236 LEU A CG  1 
ATOM   1624  C CD1 . LEU A 1 215 ? 170.206 190.940 199.450 1.00 16.43  ? 236 LEU A CD1 1 
ATOM   1625  C CD2 . LEU A 1 215 ? 169.800 192.775 201.096 1.00 16.43  ? 236 LEU A CD2 1 
ATOM   1626  N N   . THR A 1 216 ? 164.729 191.510 200.269 1.00 17.41  ? 237 THR A N   1 
ATOM   1627  C CA  . THR A 1 216 ? 163.519 192.010 199.620 1.00 17.41  ? 237 THR A CA  1 
ATOM   1628  C C   . THR A 1 216 ? 162.616 192.740 200.613 1.00 17.41  ? 237 THR A C   1 
ATOM   1629  O O   . THR A 1 216 ? 162.078 193.810 200.300 1.00 17.41  ? 237 THR A O   1 
ATOM   1630  C CB  . THR A 1 216 ? 162.792 190.842 198.945 1.00 17.41  ? 237 THR A CB  1 
ATOM   1631  O OG1 . THR A 1 216 ? 163.589 190.359 197.857 1.00 17.41  ? 237 THR A OG1 1 
ATOM   1632  C CG2 . THR A 1 216 ? 161.437 191.261 198.395 1.00 17.41  ? 237 THR A CG2 1 
ATOM   1633  N N   . SER A 1 217 ? 162.481 192.210 201.833 1.00 21.06  ? 238 SER A N   1 
ATOM   1634  C CA  . SER A 1 217 ? 161.658 192.859 202.846 1.00 21.06  ? 238 SER A CA  1 
ATOM   1635  C C   . SER A 1 217 ? 162.311 194.122 203.393 1.00 21.06  ? 238 SER A C   1 
ATOM   1636  O O   . SER A 1 217 ? 161.613 195.104 203.668 1.00 21.06  ? 238 SER A O   1 
ATOM   1637  C CB  . SER A 1 217 ? 161.361 191.883 203.984 1.00 21.06  ? 238 SER A CB  1 
ATOM   1638  O OG  . SER A 1 217 ? 160.594 192.505 204.999 1.00 21.06  ? 238 SER A OG  1 
ATOM   1639  N N   . SER A 1 218 ? 163.636 194.128 203.558 1.00 20.29  ? 239 SER A N   1 
ATOM   1640  C CA  . SER A 1 218 ? 164.315 195.332 204.016 1.00 20.29  ? 239 SER A CA  1 
ATOM   1641  C C   . SER A 1 218 ? 164.503 196.362 202.912 1.00 20.29  ? 239 SER A C   1 
ATOM   1642  O O   . SER A 1 218 ? 164.833 197.514 203.213 1.00 20.29  ? 239 SER A O   1 
ATOM   1643  C CB  . SER A 1 218 ? 165.676 194.975 204.618 1.00 20.29  ? 239 SER A CB  1 
ATOM   1644  O OG  . SER A 1 218 ? 165.529 194.139 205.752 1.00 20.29  ? 239 SER A OG  1 
ATOM   1645  N N   . LEU A 1 219 ? 164.307 195.980 201.652 1.00 21.03  ? 240 LEU A N   1 
ATOM   1646  C CA  . LEU A 1 219 ? 164.437 196.919 200.548 1.00 21.03  ? 240 LEU A CA  1 
ATOM   1647  C C   . LEU A 1 219 ? 163.181 197.750 200.323 1.00 21.03  ? 240 LEU A C   1 
ATOM   1648  O O   . LEU A 1 219 ? 163.286 198.924 199.952 1.00 21.03  ? 240 LEU A O   1 
ATOM   1649  C CB  . LEU A 1 219 ? 164.794 196.168 199.262 1.00 21.03  ? 240 LEU A CB  1 
ATOM   1650  C CG  . LEU A 1 219 ? 165.327 196.997 198.092 1.00 21.03  ? 240 LEU A CG  1 
ATOM   1651  C CD1 . LEU A 1 219 ? 166.301 198.052 198.579 1.00 21.03  ? 240 LEU A CD1 1 
ATOM   1652  C CD2 . LEU A 1 219 ? 165.983 196.096 197.060 1.00 21.03  ? 240 LEU A CD2 1 
ATOM   1653  N N   . GLY A 1 220 ? 162.002 197.177 200.539 1.00 27.37  ? 241 GLY A N   1 
ATOM   1654  C CA  . GLY A 1 220 ? 160.747 197.876 200.327 1.00 27.37  ? 241 GLY A CA  1 
ATOM   1655  C C   . GLY A 1 220 ? 159.812 197.220 199.335 1.00 27.37  ? 241 GLY A C   1 
ATOM   1656  O O   . GLY A 1 220 ? 158.621 197.564 199.313 1.00 27.37  ? 241 GLY A O   1 
ATOM   1657  N N   . ILE A 1 221 ? 160.289 196.295 198.507 1.00 32.04  ? 242 ILE A N   1 
ATOM   1658  C CA  . ILE A 1 221 ? 159.424 195.581 197.574 1.00 32.04  ? 242 ILE A CA  1 
ATOM   1659  C C   . ILE A 1 221 ? 158.626 194.546 198.355 1.00 32.04  ? 242 ILE A C   1 
ATOM   1660  O O   . ILE A 1 221 ? 159.199 193.684 199.028 1.00 32.04  ? 242 ILE A O   1 
ATOM   1661  C CB  . ILE A 1 221 ? 160.229 194.918 196.441 1.00 32.04  ? 242 ILE A CB  1 
ATOM   1662  C CG1 . ILE A 1 221 ? 160.909 195.952 195.529 1.00 32.04  ? 242 ILE A CG1 1 
ATOM   1663  C CG2 . ILE A 1 221 ? 159.342 193.993 195.618 1.00 32.04  ? 242 ILE A CG2 1 
ATOM   1664  C CD1 . ILE A 1 221 ? 162.336 196.330 195.899 1.00 32.04  ? 242 ILE A CD1 1 
ATOM   1665  N N   . SER A 1 222 ? 157.299 194.632 198.269 1.00 57.34  ? 243 SER A N   1 
ATOM   1666  C CA  . SER A 1 222 ? 156.394 193.700 198.940 1.00 57.34  ? 243 SER A CA  1 
ATOM   1667  C C   . SER A 1 222 ? 155.414 193.179 197.894 1.00 57.34  ? 243 SER A C   1 
ATOM   1668  O O   . SER A 1 222 ? 154.349 193.766 197.682 1.00 57.34  ? 243 SER A O   1 
ATOM   1669  C CB  . SER A 1 222 ? 155.678 194.370 200.108 1.00 57.34  ? 243 SER A CB  1 
ATOM   1670  O OG  . SER A 1 222 ? 154.790 193.470 200.747 1.00 57.34  ? 243 SER A OG  1 
ATOM   1671  N N   . SER A 1 223 ? 155.783 192.083 197.235 1.00 76.29  ? 244 SER A N   1 
ATOM   1672  C CA  . SER A 1 223 ? 154.902 191.464 196.256 1.00 76.29  ? 244 SER A CA  1 
ATOM   1673  C C   . SER A 1 223 ? 153.737 190.774 196.953 1.00 76.29  ? 244 SER A C   1 
ATOM   1674  O O   . SER A 1 223 ? 153.917 190.069 197.950 1.00 76.29  ? 244 SER A O   1 
ATOM   1675  C CB  . SER A 1 223 ? 155.677 190.462 195.403 1.00 76.29  ? 244 SER A CB  1 
ATOM   1676  O OG  . SER A 1 223 ? 156.145 189.379 196.186 1.00 76.29  ? 244 SER A OG  1 
ATOM   1677  N N   . THR A 1 224 ? 152.533 190.977 196.418 1.00 86.15  ? 245 THR A N   1 
ATOM   1678  C CA  . THR A 1 224 ? 151.324 190.452 197.035 1.00 86.15  ? 245 THR A CA  1 
ATOM   1679  C C   . THR A 1 224 ? 150.521 189.521 196.139 1.00 86.15  ? 245 THR A C   1 
ATOM   1680  O O   . THR A 1 224 ? 149.592 188.876 196.637 1.00 86.15  ? 245 THR A O   1 
ATOM   1681  C CB  . THR A 1 224 ? 150.412 191.600 197.496 1.00 86.15  ? 245 THR A CB  1 
ATOM   1682  O OG1 . THR A 1 224 ? 149.314 191.070 198.248 1.00 86.15  ? 245 THR A OG1 1 
ATOM   1683  C CG2 . THR A 1 224 ? 149.878 192.376 196.300 1.00 86.15  ? 245 THR A CG2 1 
ATOM   1684  N N   . ASP A 1 225 ? 150.838 189.425 194.854 1.00 81.64  ? 246 ASP A N   1 
ATOM   1685  C CA  . ASP A 1 225 ? 150.122 188.556 193.935 1.00 81.64  ? 246 ASP A CA  1 
ATOM   1686  C C   . ASP A 1 225 ? 150.991 187.357 193.565 1.00 81.64  ? 246 ASP A C   1 
ATOM   1687  O O   . ASP A 1 225 ? 152.131 187.216 194.016 1.00 81.64  ? 246 ASP A O   1 
ATOM   1688  C CB  . ASP A 1 225 ? 149.678 189.332 192.691 1.00 81.64  ? 246 ASP A CB  1 
ATOM   1689  C CG  . ASP A 1 225 ? 150.818 190.078 192.022 1.00 81.64  ? 246 ASP A CG  1 
ATOM   1690  O OD1 . ASP A 1 225 ? 151.916 190.155 192.610 1.00 81.64  ? 246 ASP A OD1 1 
ATOM   1691  O OD2 . ASP A 1 225 ? 150.614 190.588 190.900 1.00 81.64  ? 246 ASP A OD2 1 
ATOM   1692  N N   . PHE A 1 226 ? 150.430 186.487 192.727 1.00 63.94  ? 247 PHE A N   1 
ATOM   1693  C CA  . PHE A 1 226 ? 151.123 185.266 192.339 1.00 63.94  ? 247 PHE A CA  1 
ATOM   1694  C C   . PHE A 1 226 ? 152.220 185.523 191.312 1.00 63.94  ? 247 PHE A C   1 
ATOM   1695  O O   . PHE A 1 226 ? 153.230 184.811 191.303 1.00 63.94  ? 247 PHE A O   1 
ATOM   1696  C CB  . PHE A 1 226 ? 150.111 184.255 191.796 1.00 63.94  ? 247 PHE A CB  1 
ATOM   1697  C CG  . PHE A 1 226 ? 150.717 182.944 191.405 1.00 63.94  ? 247 PHE A CG  1 
ATOM   1698  C CD1 . PHE A 1 226 ? 151.095 182.028 192.374 1.00 63.94  ? 247 PHE A CD1 1 
ATOM   1699  C CD2 . PHE A 1 226 ? 150.906 182.625 190.068 1.00 63.94  ? 247 PHE A CD2 1 
ATOM   1700  C CE1 . PHE A 1 226 ? 151.654 180.819 192.017 1.00 63.94  ? 247 PHE A CE1 1 
ATOM   1701  C CE2 . PHE A 1 226 ? 151.467 181.420 189.704 1.00 63.94  ? 247 PHE A CE2 1 
ATOM   1702  C CZ  . PHE A 1 226 ? 151.840 180.517 190.679 1.00 63.94  ? 247 PHE A CZ  1 
ATOM   1703  N N   . ASN A 1 227 ? 152.042 186.527 190.449 1.00 66.34  ? 248 ASN A N   1 
ATOM   1704  C CA  . ASN A 1 227 ? 152.979 186.743 189.350 1.00 66.34  ? 248 ASN A CA  1 
ATOM   1705  C C   . ASN A 1 227 ? 154.293 187.341 189.839 1.00 66.34  ? 248 ASN A C   1 
ATOM   1706  O O   . ASN A 1 227 ? 155.369 186.948 189.375 1.00 66.34  ? 248 ASN A O   1 
ATOM   1707  C CB  . ASN A 1 227 ? 152.336 187.640 188.292 1.00 66.34  ? 248 ASN A CB  1 
ATOM   1708  C CG  . ASN A 1 227 ? 153.120 187.670 186.996 1.00 66.34  ? 248 ASN A CG  1 
ATOM   1709  O OD1 . ASN A 1 227 ? 154.147 188.338 186.892 1.00 66.34  ? 248 ASN A OD1 1 
ATOM   1710  N ND2 . ASN A 1 227 ? 152.635 186.942 185.996 1.00 66.34  ? 248 ASN A ND2 1 
ATOM   1711  N N   . ASP A 1 228 ? 154.229 188.289 190.768 1.00 72.76  ? 249 ASP A N   1 
ATOM   1712  C CA  . ASP A 1 228 ? 155.422 188.946 191.283 1.00 72.76  ? 249 ASP A CA  1 
ATOM   1713  C C   . ASP A 1 228 ? 156.057 188.185 192.440 1.00 72.76  ? 249 ASP A C   1 
ATOM   1714  O O   . ASP A 1 228 ? 157.089 188.623 192.960 1.00 72.76  ? 249 ASP A O   1 
ATOM   1715  C CB  . ASP A 1 228 ? 155.080 190.377 191.718 1.00 72.76  ? 249 ASP A CB  1 
ATOM   1716  C CG  . ASP A 1 228 ? 156.257 191.327 191.599 1.00 72.76  ? 249 ASP A CG  1 
ATOM   1717  O OD1 . ASP A 1 228 ? 157.319 190.910 191.095 1.00 72.76  ? 249 ASP A OD1 1 
ATOM   1718  O OD2 . ASP A 1 228 ? 156.116 192.498 192.009 1.00 72.76  ? 249 ASP A OD2 1 
ATOM   1719  N N   . LEU A 1 229 ? 155.465 187.064 192.860 1.00 60.06  ? 250 LEU A N   1 
ATOM   1720  C CA  . LEU A 1 229 ? 156.040 186.281 193.950 1.00 60.06  ? 250 LEU A CA  1 
ATOM   1721  C C   . LEU A 1 229 ? 157.289 185.536 193.495 1.00 60.06  ? 250 LEU A C   1 
ATOM   1722  O O   . LEU A 1 229 ? 158.310 185.531 194.193 1.00 60.06  ? 250 LEU A O   1 
ATOM   1723  C CB  . LEU A 1 229 ? 154.997 185.307 194.497 1.00 60.06  ? 250 LEU A CB  1 
ATOM   1724  C CG  . LEU A 1 229 ? 155.408 184.497 195.726 1.00 60.06  ? 250 LEU A CG  1 
ATOM   1725  C CD1 . LEU A 1 229 ? 155.708 185.421 196.891 1.00 60.06  ? 250 LEU A CD1 1 
ATOM   1726  C CD2 . LEU A 1 229 ? 154.320 183.505 196.094 1.00 60.06  ? 250 LEU A CD2 1 
ATOM   1727  N N   . LEU A 1 230 ? 157.229 184.898 192.323 1.00 57.56  ? 251 LEU A N   1 
ATOM   1728  C CA  . LEU A 1 230 ? 158.402 184.220 191.784 1.00 57.56  ? 251 LEU A CA  1 
ATOM   1729  C C   . LEU A 1 230 ? 159.421 185.205 191.229 1.00 57.56  ? 251 LEU A C   1 
ATOM   1730  O O   . LEU A 1 230 ? 160.620 184.904 191.211 1.00 57.56  ? 251 LEU A O   1 
ATOM   1731  C CB  . LEU A 1 230 ? 157.990 183.226 190.697 1.00 57.56  ? 251 LEU A CB  1 
ATOM   1732  C CG  . LEU A 1 230 ? 157.230 181.986 191.166 1.00 57.56  ? 251 LEU A CG  1 
ATOM   1733  C CD1 . LEU A 1 230 ? 156.256 181.516 190.098 1.00 57.56  ? 251 LEU A CD1 1 
ATOM   1734  C CD2 . LEU A 1 230 ? 158.206 180.880 191.532 1.00 57.56  ? 251 LEU A CD2 1 
ATOM   1735  N N   . THR A 1 231 ? 158.964 186.362 190.760 1.00 57.28  ? 252 THR A N   1 
ATOM   1736  C CA  . THR A 1 231 ? 159.868 187.426 190.350 1.00 57.28  ? 252 THR A CA  1 
ATOM   1737  C C   . THR A 1 231 ? 160.559 188.002 191.583 1.00 57.28  ? 252 THR A C   1 
ATOM   1738  O O   . THR A 1 231 ? 159.958 188.111 192.655 1.00 57.28  ? 252 THR A O   1 
ATOM   1739  C CB  . THR A 1 231 ? 159.086 188.509 189.598 1.00 57.28  ? 252 THR A CB  1 
ATOM   1740  O OG1 . THR A 1 231 ? 158.266 187.891 188.600 1.00 57.28  ? 252 THR A OG1 1 
ATOM   1741  C CG2 . THR A 1 231 ? 160.016 189.498 188.899 1.00 57.28  ? 252 THR A CG2 1 
ATOM   1742  N N   . GLY A 1 232 ? 161.829 188.365 191.433 1.00 31.44  ? 253 GLY A N   1 
ATOM   1743  C CA  . GLY A 1 232 ? 162.623 188.768 192.573 1.00 31.44  ? 253 GLY A CA  1 
ATOM   1744  C C   . GLY A 1 232 ? 164.064 188.332 192.440 1.00 31.44  ? 253 GLY A C   1 
ATOM   1745  O O   . GLY A 1 232 ? 164.878 188.573 193.334 1.00 31.44  ? 253 GLY A O   1 
ATOM   1746  N N   . LYS A 1 233 ? 164.383 187.667 191.333 1.00 27.87  ? 254 LYS A N   1 
ATOM   1747  C CA  . LYS A 1 233 ? 165.759 187.374 190.961 1.00 27.87  ? 254 LYS A CA  1 
ATOM   1748  C C   . LYS A 1 233 ? 166.297 188.361 189.934 1.00 27.87  ? 254 LYS A C   1 
ATOM   1749  O O   . LYS A 1 233 ? 167.392 188.153 189.401 1.00 27.87  ? 254 LYS A O   1 
ATOM   1750  C CB  . LYS A 1 233 ? 165.872 185.948 190.420 1.00 27.87  ? 254 LYS A CB  1 
ATOM   1751  C CG  . LYS A 1 233 ? 164.953 184.946 191.095 1.00 27.87  ? 254 LYS A CG  1 
ATOM   1752  C CD  . LYS A 1 233 ? 165.100 183.564 190.476 1.00 27.87  ? 254 LYS A CD  1 
ATOM   1753  C CE  . LYS A 1 233 ? 164.080 182.591 191.043 1.00 27.87  ? 254 LYS A CE  1 
ATOM   1754  N NZ  . LYS A 1 233 ? 164.123 182.546 192.530 1.00 27.87  ? 254 LYS A NZ  1 
ATOM   1755  N N   . LEU A 1 234 ? 165.550 189.429 189.642 1.00 29.92  ? 255 LEU A N   1 
ATOM   1756  C CA  . LEU A 1 234 ? 165.907 190.387 188.601 1.00 29.92  ? 255 LEU A CA  1 
ATOM   1757  C C   . LEU A 1 234 ? 165.914 191.814 189.138 1.00 29.92  ? 255 LEU A C   1 
ATOM   1758  O O   . LEU A 1 234 ? 165.637 192.760 188.397 1.00 29.92  ? 255 LEU A O   1 
ATOM   1759  C CB  . LEU A 1 234 ? 164.952 190.279 187.411 1.00 29.92  ? 255 LEU A CB  1 
ATOM   1760  C CG  . LEU A 1 234 ? 164.697 188.900 186.800 1.00 29.92  ? 255 LEU A CG  1 
ATOM   1761  C CD1 . LEU A 1 234 ? 163.535 188.953 185.820 1.00 29.92  ? 255 LEU A CD1 1 
ATOM   1762  C CD2 . LEU A 1 234 ? 165.950 188.370 186.124 1.00 29.92  ? 255 LEU A CD2 1 
ATOM   1763  N N   . ILE A 1 235 ? 166.213 191.985 190.427 1.00 25.27  ? 256 ILE A N   1 
ATOM   1764  C CA  . ILE A 1 235 ? 166.194 193.318 191.025 1.00 25.27  ? 256 ILE A CA  1 
ATOM   1765  C C   . ILE A 1 235 ? 167.405 194.128 190.575 1.00 25.27  ? 256 ILE A C   1 
ATOM   1766  O O   . ILE A 1 235 ? 167.283 195.309 190.227 1.00 25.27  ? 256 ILE A O   1 
ATOM   1767  C CB  . ILE A 1 235 ? 166.121 193.215 192.559 1.00 25.27  ? 256 ILE A CB  1 
ATOM   1768  C CG1 . ILE A 1 235 ? 165.076 192.177 192.975 1.00 25.27  ? 256 ILE A CG1 1 
ATOM   1769  C CG2 . ILE A 1 235 ? 165.822 194.574 193.173 1.00 25.27  ? 256 ILE A CG2 1 
ATOM   1770  C CD1 . ILE A 1 235 ? 163.647 192.607 192.745 1.00 25.27  ? 256 ILE A CD1 1 
ATOM   1771  N N   . THR A 1 236 ? 168.592 193.503 190.592 1.00 25.88  ? 257 THR A N   1 
ATOM   1772  C CA  . THR A 1 236 ? 169.897 194.055 190.208 1.00 25.88  ? 257 THR A CA  1 
ATOM   1773  C C   . THR A 1 236 ? 170.292 195.326 190.962 1.00 25.88  ? 257 THR A C   1 
ATOM   1774  O O   . THR A 1 236 ? 169.637 195.722 191.931 1.00 25.88  ? 257 THR A O   1 
ATOM   1775  C CB  . THR A 1 236 ? 169.972 194.314 188.694 1.00 25.88  ? 257 THR A CB  1 
ATOM   1776  O OG1 . THR A 1 236 ? 169.170 195.450 188.352 1.00 25.88  ? 257 THR A OG1 1 
ATOM   1777  C CG2 . THR A 1 236 ? 169.500 193.095 187.910 1.00 25.88  ? 257 THR A CG2 1 
ATOM   1778  N N   . GLY A 1 237 ? 171.383 195.950 190.543 1.00 29.00  ? 258 GLY A N   1 
ATOM   1779  C CA  . GLY A 1 237 ? 171.873 197.150 191.190 1.00 29.00  ? 258 GLY A CA  1 
ATOM   1780  C C   . GLY A 1 237 ? 173.342 197.364 190.919 1.00 29.00  ? 258 GLY A C   1 
ATOM   1781  O O   . GLY A 1 237 ? 174.063 196.466 190.485 1.00 29.00  ? 258 GLY A O   1 
ATOM   1782  N N   . SER A 1 238 ? 173.798 198.585 191.197 1.00 34.22  ? 259 SER A N   1 
ATOM   1783  C CA  . SER A 1 238 ? 175.168 198.989 190.912 1.00 34.22  ? 259 SER A CA  1 
ATOM   1784  C C   . SER A 1 238 ? 175.770 199.712 192.111 1.00 34.22  ? 259 SER A C   1 
ATOM   1785  O O   . SER A 1 238 ? 175.061 200.151 193.020 1.00 34.22  ? 259 SER A O   1 
ATOM   1786  C CB  . SER A 1 238 ? 175.239 199.890 189.674 1.00 34.22  ? 259 SER A CB  1 
ATOM   1787  O OG  . SER A 1 238 ? 176.552 200.383 189.479 1.00 34.22  ? 259 SER A OG  1 
ATOM   1788  N N   . ILE A 1 239 ? 177.101 199.838 192.092 1.00 49.69  ? 260 ILE A N   1 
ATOM   1789  C CA  . ILE A 1 239 ? 177.862 200.469 193.166 1.00 49.69  ? 260 ILE A CA  1 
ATOM   1790  C C   . ILE A 1 239 ? 178.004 201.954 192.866 1.00 49.69  ? 260 ILE A C   1 
ATOM   1791  O O   . ILE A 1 239 ? 178.240 202.346 191.718 1.00 49.69  ? 260 ILE A O   1 
ATOM   1792  C CB  . ILE A 1 239 ? 179.247 199.810 193.316 1.00 49.69  ? 260 ILE A CB  1 
ATOM   1793  C CG1 . ILE A 1 239 ? 179.142 198.291 193.223 1.00 49.69  ? 260 ILE A CG1 1 
ATOM   1794  C CG2 . ILE A 1 239 ? 179.891 200.196 194.636 1.00 49.69  ? 260 ILE A CG2 1 
ATOM   1795  C CD1 . ILE A 1 239 ? 180.471 197.612 193.056 1.00 49.69  ? 260 ILE A CD1 1 
ATOM   1796  N N   . ILE A 1 240 ? 177.854 202.790 193.891 1.00 23.79  ? 261 ILE A N   1 
ATOM   1797  C CA  . ILE A 1 240 ? 178.145 204.211 193.750 1.00 23.79  ? 261 ILE A CA  1 
ATOM   1798  C C   . ILE A 1 240 ? 179.235 204.700 194.695 1.00 23.79  ? 261 ILE A C   1 
ATOM   1799  O O   . ILE A 1 240 ? 179.833 205.753 194.420 1.00 23.79  ? 261 ILE A O   1 
ATOM   1800  C CB  . ILE A 1 240 ? 176.877 205.080 193.913 1.00 23.79  ? 261 ILE A CB  1 
ATOM   1801  C CG1 . ILE A 1 240 ? 176.297 204.954 195.321 1.00 23.79  ? 261 ILE A CG1 1 
ATOM   1802  C CG2 . ILE A 1 240 ? 175.836 204.735 192.856 1.00 23.79  ? 261 ILE A CG2 1 
ATOM   1803  C CD1 . ILE A 1 240 ? 175.236 205.980 195.637 1.00 23.79  ? 261 ILE A CD1 1 
ATOM   1804  N N   . TRP A 1 241 ? 179.540 204.001 195.792 1.00 27.78  ? 262 TRP A N   1 
ATOM   1805  C CA  . TRP A 1 241 ? 180.621 204.472 196.654 1.00 27.78  ? 262 TRP A CA  1 
ATOM   1806  C C   . TRP A 1 241 ? 181.302 203.302 197.350 1.00 27.78  ? 262 TRP A C   1 
ATOM   1807  O O   . TRP A 1 241 ? 180.678 202.278 197.629 1.00 27.78  ? 262 TRP A O   1 
ATOM   1808  C CB  . TRP A 1 241 ? 180.117 205.480 197.692 1.00 27.78  ? 262 TRP A CB  1 
ATOM   1809  C CG  . TRP A 1 241 ? 181.197 206.304 198.315 1.00 27.78  ? 262 TRP A CG  1 
ATOM   1810  C CD1 . TRP A 1 241 ? 181.628 206.239 199.603 1.00 27.78  ? 262 TRP A CD1 1 
ATOM   1811  C CD2 . TRP A 1 241 ? 181.980 207.320 197.679 1.00 27.78  ? 262 TRP A CD2 1 
ATOM   1812  N NE1 . TRP A 1 241 ? 182.634 207.150 199.814 1.00 27.78  ? 262 TRP A NE1 1 
ATOM   1813  C CE2 . TRP A 1 241 ? 182.868 207.827 198.648 1.00 27.78  ? 262 TRP A CE2 1 
ATOM   1814  C CE3 . TRP A 1 241 ? 182.016 207.851 196.386 1.00 27.78  ? 262 TRP A CE3 1 
ATOM   1815  C CZ2 . TRP A 1 241 ? 183.784 208.837 198.365 1.00 27.78  ? 262 TRP A CZ2 1 
ATOM   1816  C CZ3 . TRP A 1 241 ? 182.925 208.854 196.107 1.00 27.78  ? 262 TRP A CZ3 1 
ATOM   1817  C CH2 . TRP A 1 241 ? 183.797 209.337 197.092 1.00 27.78  ? 262 TRP A CH2 1 
ATOM   1818  N N   . ALA A 1 242 ? 182.584 203.489 197.657 1.00 19.42  ? 263 ALA A N   1 
ATOM   1819  C CA  . ALA A 1 242 ? 183.468 202.432 198.146 1.00 19.42  ? 263 ALA A CA  1 
ATOM   1820  C C   . ALA A 1 242 ? 184.312 202.926 199.318 1.00 19.42  ? 263 ALA A C   1 
ATOM   1821  O O   . ALA A 1 242 ? 185.542 202.877 199.276 1.00 19.42  ? 263 ALA A O   1 
ATOM   1822  C CB  . ALA A 1 242 ? 184.358 201.913 197.023 1.00 19.42  ? 263 ALA A CB  1 
ATOM   1823  N N   . ASP A 1 243 ? 183.655 203.452 200.358 1.00 30.68  ? 264 ASP A N   1 
ATOM   1824  C CA  . ASP A 1 243 ? 184.349 204.185 201.417 1.00 30.68  ? 264 ASP A CA  1 
ATOM   1825  C C   . ASP A 1 243 ? 185.261 203.279 202.240 1.00 30.68  ? 264 ASP A C   1 
ATOM   1826  O O   . ASP A 1 243 ? 184.850 202.208 202.703 1.00 30.68  ? 264 ASP A O   1 
ATOM   1827  C CB  . ASP A 1 243 ? 183.342 204.869 202.339 1.00 30.68  ? 264 ASP A CB  1 
ATOM   1828  C CG  . ASP A 1 243 ? 183.960 206.000 203.141 1.00 30.68  ? 264 ASP A CG  1 
ATOM   1829  O OD1 . ASP A 1 243 ? 185.133 206.346 202.885 1.00 30.68  ? 264 ASP A OD1 1 
ATOM   1830  O OD2 . ASP A 1 243 ? 183.276 206.545 204.031 1.00 30.68  ? 264 ASP A OD2 1 
ATOM   1831  N N   . THR A 1 244 ? 186.501 203.738 202.432 1.00 29.95  ? 265 THR A N   1 
ATOM   1832  C CA  . THR A 1 244 ? 187.581 202.943 202.998 1.00 29.95  ? 265 THR A CA  1 
ATOM   1833  C C   . THR A 1 244 ? 187.738 203.105 204.502 1.00 29.95  ? 265 THR A C   1 
ATOM   1834  O O   . THR A 1 244 ? 188.341 202.234 205.138 1.00 29.95  ? 265 THR A O   1 
ATOM   1835  C CB  . THR A 1 244 ? 188.911 203.312 202.330 1.00 29.95  ? 265 THR A CB  1 
ATOM   1836  O OG1 . THR A 1 244 ? 189.318 204.612 202.772 1.00 29.95  ? 265 THR A OG1 1 
ATOM   1837  C CG2 . THR A 1 244 ? 188.759 203.343 200.822 1.00 29.95  ? 265 THR A CG2 1 
ATOM   1838  N N   . GLN A 1 245 ? 187.229 204.193 205.084 1.00 33.09  ? 266 GLN A N   1 
ATOM   1839  C CA  . GLN A 1 245 ? 187.428 204.432 206.510 1.00 33.09  ? 266 GLN A CA  1 
ATOM   1840  C C   . GLN A 1 245 ? 186.551 203.515 207.353 1.00 33.09  ? 266 GLN A C   1 
ATOM   1841  O O   . GLN A 1 245 ? 187.048 202.809 208.236 1.00 33.09  ? 266 GLN A O   1 
ATOM   1842  C CB  . GLN A 1 245 ? 187.151 205.899 206.839 1.00 33.09  ? 266 GLN A CB  1 
ATOM   1843  C CG  . GLN A 1 245 ? 188.337 206.816 206.596 1.00 33.09  ? 266 GLN A CG  1 
ATOM   1844  C CD  . GLN A 1 245 ? 187.944 208.278 206.553 1.00 33.09  ? 266 GLN A CD  1 
ATOM   1845  O OE1 . GLN A 1 245 ? 187.250 208.773 207.440 1.00 33.09  ? 266 GLN A OE1 1 
ATOM   1846  N NE2 . GLN A 1 245 ? 188.388 208.979 205.516 1.00 33.09  ? 266 GLN A NE2 1 
ATOM   1847  N N   . GLY A 1 246 ? 185.249 203.512 207.093 1.00 31.23  ? 267 GLY A N   1 
ATOM   1848  C CA  . GLY A 1 246 ? 184.360 202.562 207.725 1.00 31.23  ? 267 GLY A CA  1 
ATOM   1849  C C   . GLY A 1 246 ? 184.292 201.214 207.052 1.00 31.23  ? 267 GLY A C   1 
ATOM   1850  O O   . GLY A 1 246 ? 183.612 200.323 207.571 1.00 31.23  ? 267 GLY A O   1 
ATOM   1851  N N   . HIS A 1 247 ? 184.993 201.062 205.920 1.00 29.30  ? 268 HIS A N   1 
ATOM   1852  C CA  . HIS A 1 247 ? 185.025 199.852 205.089 1.00 29.30  ? 268 HIS A CA  1 
ATOM   1853  C C   . HIS A 1 247 ? 183.619 199.425 204.665 1.00 29.30  ? 268 HIS A C   1 
ATOM   1854  O O   . HIS A 1 247 ? 183.140 198.342 205.003 1.00 29.30  ? 268 HIS A O   1 
ATOM   1855  C CB  . HIS A 1 247 ? 185.757 198.702 205.795 1.00 29.30  ? 268 HIS A CB  1 
ATOM   1856  C CG  . HIS A 1 247 ? 186.977 199.128 206.548 1.00 29.30  ? 268 HIS A CG  1 
ATOM   1857  N ND1 . HIS A 1 247 ? 188.214 199.252 205.952 1.00 29.30  ? 268 HIS A ND1 1 
ATOM   1858  C CD2 . HIS A 1 247 ? 187.152 199.456 207.850 1.00 29.30  ? 268 HIS A CD2 1 
ATOM   1859  C CE1 . HIS A 1 247 ? 189.098 199.638 206.855 1.00 29.30  ? 268 HIS A CE1 1 
ATOM   1860  N NE2 . HIS A 1 247 ? 188.479 199.770 208.014 1.00 29.30  ? 268 HIS A NE2 1 
ATOM   1861  N N   . TYR A 1 248 ? 182.952 200.302 203.917 1.00 27.30  ? 269 TYR A N   1 
ATOM   1862  C CA  . TYR A 1 248 ? 181.590 200.007 203.495 1.00 27.30  ? 269 TYR A CA  1 
ATOM   1863  C C   . TYR A 1 248 ? 181.388 200.414 202.044 1.00 27.30  ? 269 TYR A C   1 
ATOM   1864  O O   . TYR A 1 248 ? 182.150 201.201 201.477 1.00 27.30  ? 269 TYR A O   1 
ATOM   1865  C CB  . TYR A 1 248 ? 180.542 200.678 204.401 1.00 27.30  ? 269 TYR A CB  1 
ATOM   1866  C CG  . TYR A 1 248 ? 180.581 202.189 204.467 1.00 27.30  ? 269 TYR A CG  1 
ATOM   1867  C CD1 . TYR A 1 248 ? 181.417 202.843 205.363 1.00 27.30  ? 269 TYR A CD1 1 
ATOM   1868  C CD2 . TYR A 1 248 ? 179.747 202.959 203.664 1.00 27.30  ? 269 TYR A CD2 1 
ATOM   1869  C CE1 . TYR A 1 248 ? 181.443 204.224 205.437 1.00 27.30  ? 269 TYR A CE1 1 
ATOM   1870  C CE2 . TYR A 1 248 ? 179.766 204.340 203.731 1.00 27.30  ? 269 TYR A CE2 1 
ATOM   1871  C CZ  . TYR A 1 248 ? 180.614 204.964 204.621 1.00 27.30  ? 269 TYR A CZ  1 
ATOM   1872  O OH  . TYR A 1 248 ? 180.638 206.337 204.691 1.00 27.30  ? 269 TYR A OH  1 
ATOM   1873  N N   . LEU A 1 249 ? 180.357 199.827 201.443 1.00 49.69  ? 270 LEU A N   1 
ATOM   1874  C CA  . LEU A 1 249 ? 179.995 200.066 200.055 1.00 49.69  ? 270 LEU A CA  1 
ATOM   1875  C C   . LEU A 1 249 ? 178.584 200.630 200.006 1.00 49.69  ? 270 LEU A C   1 
ATOM   1876  O O   . LEU A 1 249 ? 177.655 200.034 200.557 1.00 49.69  ? 270 LEU A O   1 
ATOM   1877  C CB  . LEU A 1 249 ? 180.065 198.780 199.223 1.00 49.69  ? 270 LEU A CB  1 
ATOM   1878  C CG  . LEU A 1 249 ? 181.398 198.224 198.709 1.00 49.69  ? 270 LEU A CG  1 
ATOM   1879  C CD1 . LEU A 1 249 ? 182.237 197.581 199.807 1.00 49.69  ? 270 LEU A CD1 1 
ATOM   1880  C CD2 . LEU A 1 249 ? 181.145 197.233 197.585 1.00 49.69  ? 270 LEU A CD2 1 
ATOM   1881  N N   . ILE A 1 250 ? 178.424 201.767 199.340 1.00 23.10  ? 271 ILE A N   1 
ATOM   1882  C CA  . ILE A 1 250 ? 177.115 202.364 199.115 1.00 23.10  ? 271 ILE A CA  1 
ATOM   1883  C C   . ILE A 1 250 ? 176.647 201.921 197.739 1.00 23.10  ? 271 ILE A C   1 
ATOM   1884  O O   . ILE A 1 250 ? 177.322 202.188 196.734 1.00 23.10  ? 271 ILE A O   1 
ATOM   1885  C CB  . ILE A 1 250 ? 177.160 203.894 199.220 1.00 23.10  ? 271 ILE A CB  1 
ATOM   1886  C CG1 . ILE A 1 250 ? 177.830 204.317 200.527 1.00 23.10  ? 271 ILE A CG1 1 
ATOM   1887  C CG2 . ILE A 1 250 ? 175.757 204.472 199.121 1.00 23.10  ? 271 ILE A CG2 1 
ATOM   1888  C CD1 . ILE A 1 250 ? 177.921 205.810 200.712 1.00 23.10  ? 271 ILE A CD1 1 
ATOM   1889  N N   . LEU A 1 251 ? 175.492 201.256 197.707 1.00 25.16  ? 272 LEU A N   1 
ATOM   1890  C CA  . LEU A 1 251 ? 174.955 200.578 196.540 1.00 25.16  ? 272 LEU A CA  1 
ATOM   1891  C C   . LEU A 1 251 ? 173.598 201.173 196.191 1.00 25.16  ? 272 LEU A C   1 
ATOM   1892  O O   . LEU A 1 251 ? 172.833 201.561 197.081 1.00 25.16  ? 272 LEU A O   1 
ATOM   1893  C CB  . LEU A 1 251 ? 174.807 199.078 196.821 1.00 25.16  ? 272 LEU A CB  1 
ATOM   1894  C CG  . LEU A 1 251 ? 174.667 198.078 195.675 1.00 25.16  ? 272 LEU A CG  1 
ATOM   1895  C CD1 . LEU A 1 251 ? 176.024 197.733 195.121 1.00 25.16  ? 272 LEU A CD1 1 
ATOM   1896  C CD2 . LEU A 1 251 ? 173.959 196.823 196.146 1.00 25.16  ? 272 LEU A CD2 1 
ATOM   1897  N N   . ARG A 1 252 ? 173.302 201.250 194.896 1.00 21.63  ? 273 ARG A N   1 
ATOM   1898  C CA  . ARG A 1 252 ? 172.024 201.748 194.406 1.00 21.63  ? 273 ARG A CA  1 
ATOM   1899  C C   . ARG A 1 252 ? 171.340 200.652 193.603 1.00 21.63  ? 273 ARG A C   1 
ATOM   1900  O O   . ARG A 1 252 ? 171.934 200.101 192.671 1.00 21.63  ? 273 ARG A O   1 
ATOM   1901  C CB  . ARG A 1 252 ? 172.211 203.001 193.547 1.00 21.63  ? 273 ARG A CB  1 
ATOM   1902  C CG  . ARG A 1 252 ? 170.978 203.402 192.760 1.00 21.63  ? 273 ARG A CG  1 
ATOM   1903  C CD  . ARG A 1 252 ? 171.069 204.836 192.274 1.00 21.63  ? 273 ARG A CD  1 
ATOM   1904  N NE  . ARG A 1 252 ? 170.845 205.786 193.357 1.00 21.63  ? 273 ARG A NE  1 
ATOM   1905  C CZ  . ARG A 1 252 ? 170.649 207.086 193.185 1.00 21.63  ? 273 ARG A CZ  1 
ATOM   1906  N NH1 . ARG A 1 252 ? 170.614 207.625 191.978 1.00 21.63  ? 273 ARG A NH1 1 
ATOM   1907  N NH2 . ARG A 1 252 ? 170.477 207.863 194.250 1.00 21.63  ? 273 ARG A NH2 1 
ATOM   1908  N N   . VAL A 1 253 ? 170.093 200.344 193.961 1.00 28.85  ? 274 VAL A N   1 
ATOM   1909  C CA  . VAL A 1 253 ? 169.335 199.273 193.331 1.00 28.85  ? 274 VAL A CA  1 
ATOM   1910  C C   . VAL A 1 253 ? 168.064 199.853 192.725 1.00 28.85  ? 274 VAL A C   1 
ATOM   1911  O O   . VAL A 1 253 ? 167.634 200.963 193.053 1.00 28.85  ? 274 VAL A O   1 
ATOM   1912  C CB  . VAL A 1 253 ? 168.993 198.146 194.322 1.00 28.85  ? 274 VAL A CB  1 
ATOM   1913  C CG1 . VAL A 1 253 ? 170.251 197.413 194.751 1.00 28.85  ? 274 VAL A CG1 1 
ATOM   1914  C CG2 . VAL A 1 253 ? 168.285 198.720 195.520 1.00 28.85  ? 274 VAL A CG2 1 
ATOM   1915  N N   . ASN A 1 254 ? 167.457 199.074 191.832 1.00 33.79  ? 275 ASN A N   1 
ATOM   1916  C CA  . ASN A 1 254 ? 166.271 199.485 191.091 1.00 33.79  ? 275 ASN A CA  1 
ATOM   1917  C C   . ASN A 1 254 ? 165.069 198.685 191.572 1.00 33.79  ? 275 ASN A C   1 
ATOM   1918  O O   . ASN A 1 254 ? 165.086 197.450 191.536 1.00 33.79  ? 275 ASN A O   1 
ATOM   1919  C CB  . ASN A 1 254 ? 166.473 199.288 189.589 1.00 33.79  ? 275 ASN A CB  1 
ATOM   1920  C CG  . ASN A 1 254 ? 167.807 199.818 189.105 1.00 33.79  ? 275 ASN A CG  1 
ATOM   1921  O OD1 . ASN A 1 254 ? 168.673 199.054 188.682 1.00 33.79  ? 275 ASN A OD1 1 
ATOM   1922  N ND2 . ASN A 1 254 ? 167.979 201.132 189.165 1.00 33.79  ? 275 ASN A ND2 1 
ATOM   1923  N N   . ILE A 1 255 ? 164.030 199.387 192.011 1.00 37.39  ? 276 ILE A N   1 
ATOM   1924  C CA  . ILE A 1 255 ? 162.760 198.763 192.375 1.00 37.39  ? 276 ILE A CA  1 
ATOM   1925  C C   . ILE A 1 255 ? 162.017 198.425 191.087 1.00 37.39  ? 276 ILE A C   1 
ATOM   1926  O O   . ILE A 1 255 ? 161.759 199.323 190.273 1.00 37.39  ? 276 ILE A O   1 
ATOM   1927  C CB  . ILE A 1 255 ? 161.929 199.681 193.283 1.00 37.39  ? 276 ILE A CB  1 
ATOM   1928  C CG1 . ILE A 1 255 ? 162.639 199.894 194.620 1.00 37.39  ? 276 ILE A CG1 1 
ATOM   1929  C CG2 . ILE A 1 255 ? 160.532 199.120 193.492 1.00 37.39  ? 276 ILE A CG2 1 
ATOM   1930  C CD1 . ILE A 1 255 ? 162.213 201.155 195.340 1.00 37.39  ? 276 ILE A CD1 1 
ATOM   1931  N N   . PRO A 1 256 ? 161.655 197.167 190.858 1.00 42.79  ? 277 PRO A N   1 
ATOM   1932  C CA  . PRO A 1 256 ? 161.081 196.786 189.566 1.00 42.79  ? 277 PRO A CA  1 
ATOM   1933  C C   . PRO A 1 256 ? 159.601 197.122 189.459 1.00 42.79  ? 277 PRO A C   1 
ATOM   1934  O O   . PRO A 1 256 ? 158.898 197.328 190.449 1.00 42.79  ? 277 PRO A O   1 
ATOM   1935  C CB  . PRO A 1 256 ? 161.296 195.271 189.523 1.00 42.79  ? 277 PRO A CB  1 
ATOM   1936  C CG  . PRO A 1 256 ? 161.260 194.855 190.950 1.00 42.79  ? 277 PRO A CG  1 
ATOM   1937  C CD  . PRO A 1 256 ? 161.722 196.026 191.789 1.00 42.79  ? 277 PRO A CD  1 
ATOM   1938  N N   . ASP A 1 257 ? 159.142 197.171 188.211 1.00 42.83  ? 278 ASP A N   1 
ATOM   1939  C CA  . ASP A 1 257 ? 157.731 197.338 187.892 1.00 42.83  ? 278 ASP A CA  1 
ATOM   1940  C C   . ASP A 1 257 ? 157.473 196.643 186.565 1.00 42.83  ? 278 ASP A C   1 
ATOM   1941  O O   . ASP A 1 257 ? 158.250 196.806 185.620 1.00 42.83  ? 278 ASP A O   1 
ATOM   1942  C CB  . ASP A 1 257 ? 157.345 198.819 187.813 1.00 42.83  ? 278 ASP A CB  1 
ATOM   1943  C CG  . ASP A 1 257 ? 155.849 199.024 187.691 1.00 42.83  ? 278 ASP A CG  1 
ATOM   1944  O OD1 . ASP A 1 257 ? 155.089 198.124 188.103 1.00 42.83  ? 278 ASP A OD1 1 
ATOM   1945  O OD2 . ASP A 1 257 ? 155.434 200.087 187.186 1.00 42.83  ? 278 ASP A OD2 1 
ATOM   1946  N N   . LEU A 1 258 ? 156.401 195.862 186.497 1.00 41.14  ? 279 LEU A N   1 
ATOM   1947  C CA  . LEU A 1 258 ? 156.091 195.068 185.314 1.00 41.14  ? 279 LEU A CA  1 
ATOM   1948  C C   . LEU A 1 258 ? 155.045 195.801 184.485 1.00 41.14  ? 279 LEU A C   1 
ATOM   1949  O O   . LEU A 1 258 ? 153.904 195.973 184.925 1.00 41.14  ? 279 LEU A O   1 
ATOM   1950  C CB  . LEU A 1 258 ? 155.598 193.679 185.710 1.00 41.14  ? 279 LEU A CB  1 
ATOM   1951  C CG  . LEU A 1 258 ? 156.588 192.811 186.486 1.00 41.14  ? 279 LEU A CG  1 
ATOM   1952  C CD1 . LEU A 1 258 ? 155.960 191.471 186.827 1.00 41.14  ? 279 LEU A CD1 1 
ATOM   1953  C CD2 . LEU A 1 258 ? 157.871 192.621 185.695 1.00 41.14  ? 279 LEU A CD2 1 
ATOM   1954  N N   . ILE A 1 259 ? 155.429 196.227 183.286 1.00 45.16  ? 280 ILE A N   1 
ATOM   1955  C CA  . ILE A 1 259 ? 154.493 196.813 182.348 1.00 45.16  ? 280 ILE A CA  1 
ATOM   1956  C C   . ILE A 1 259 ? 154.114 195.742 181.337 1.00 45.16  ? 280 ILE A C   1 
ATOM   1957  O O   . ILE A 1 259 ? 154.788 194.718 181.188 1.00 45.16  ? 280 ILE A O   1 
ATOM   1958  C CB  . ILE A 1 259 ? 155.066 198.066 181.648 1.00 45.16  ? 280 ILE A CB  1 
ATOM   1959  C CG1 . ILE A 1 259 ? 156.258 197.693 180.766 1.00 45.16  ? 280 ILE A CG1 1 
ATOM   1960  C CG2 . ILE A 1 259 ? 155.473 199.110 182.675 1.00 45.16  ? 280 ILE A CG2 1 
ATOM   1961  C CD1 . ILE A 1 259 ? 156.713 198.808 179.852 1.00 45.16  ? 280 ILE A CD1 1 
ATOM   1962  N N   . GLU A 1 260 ? 153.012 195.973 180.635 1.00 47.78  ? 281 GLU A N   1 
ATOM   1963  C CA  . GLU A 1 260 ? 152.487 195.024 179.664 1.00 47.78  ? 281 GLU A CA  1 
ATOM   1964  C C   . GLU A 1 260 ? 152.625 195.617 178.270 1.00 47.78  ? 281 GLU A C   1 
ATOM   1965  O O   . GLU A 1 260 ? 152.143 196.726 178.015 1.00 47.78  ? 281 GLU A O   1 
ATOM   1966  C CB  . GLU A 1 260 ? 151.028 194.688 179.968 1.00 47.78  ? 281 GLU A CB  1 
ATOM   1967  C CG  . GLU A 1 260 ? 150.284 194.057 178.808 1.00 47.78  ? 281 GLU A CG  1 
ATOM   1968  C CD  . GLU A 1 260 ? 148.984 193.413 179.231 1.00 47.78  ? 281 GLU A CD  1 
ATOM   1969  O OE1 . GLU A 1 260 ? 148.722 193.341 180.450 1.00 47.78  ? 281 GLU A OE1 1 
ATOM   1970  O OE2 . GLU A 1 260 ? 148.220 192.984 178.342 1.00 47.78  ? 281 GLU A OE2 1 
ATOM   1971  N N   . VAL A 1 261 ? 153.294 194.891 177.384 1.00 43.76  ? 282 VAL A N   1 
ATOM   1972  C CA  . VAL A 1 261 ? 153.337 195.288 175.972 1.00 43.76  ? 282 VAL A CA  1 
ATOM   1973  C C   . VAL A 1 261 ? 151.948 195.094 175.359 1.00 43.76  ? 282 VAL A C   1 
ATOM   1974  O O   . VAL A 1 261 ? 151.285 194.075 175.630 1.00 43.76  ? 282 VAL A O   1 
ATOM   1975  C CB  . VAL A 1 261 ? 154.453 194.508 175.228 1.00 43.76  ? 282 VAL A CB  1 
ATOM   1976  C CG1 . VAL A 1 261 ? 154.236 192.994 175.201 1.00 43.76  ? 282 VAL A CG1 1 
ATOM   1977  C CG2 . VAL A 1 261 ? 154.681 195.044 173.811 1.00 43.76  ? 282 VAL A CG2 1 
ATOM   1978  N N   . PRO A 1 262 ? 151.404 196.087 174.649 1.00 55.74  ? 283 PRO A N   1 
ATOM   1979  C CA  . PRO A 1 262 ? 149.995 196.000 174.232 1.00 55.74  ? 283 PRO A CA  1 
ATOM   1980  C C   . PRO A 1 262 ? 149.800 195.071 173.042 1.00 55.74  ? 283 PRO A C   1 
ATOM   1981  O O   . PRO A 1 262 ? 150.531 195.142 172.051 1.00 55.74  ? 283 PRO A O   1 
ATOM   1982  C CB  . PRO A 1 262 ? 149.632 197.447 173.875 1.00 55.74  ? 283 PRO A CB  1 
ATOM   1983  C CG  . PRO A 1 262 ? 150.915 198.129 173.627 1.00 55.74  ? 283 PRO A CG  1 
ATOM   1984  C CD  . PRO A 1 262 ? 151.972 197.427 174.415 1.00 55.74  ? 283 PRO A CD  1 
ATOM   1985  N N   . GLY A 1 263 ? 148.796 194.206 173.151 1.00 65.20  ? 284 GLY A N   1 
ATOM   1986  C CA  . GLY A 1 263 ? 148.356 193.354 172.059 1.00 65.20  ? 284 GLY A CA  1 
ATOM   1987  C C   . GLY A 1 263 ? 149.331 192.288 171.611 1.00 65.20  ? 284 GLY A C   1 
ATOM   1988  O O   . GLY A 1 263 ? 149.424 192.011 170.410 1.00 65.20  ? 284 GLY A O   1 
ATOM   1989  N N   . ALA A 1 264 ? 150.055 191.676 172.544 1.00 62.03  ? 285 ALA A N   1 
ATOM   1990  C CA  . ALA A 1 264 ? 150.993 190.605 172.235 1.00 62.03  ? 285 ALA A CA  1 
ATOM   1991  C C   . ALA A 1 264 ? 150.566 189.337 172.957 1.00 62.03  ? 285 ALA A C   1 
ATOM   1992  O O   . ALA A 1 264 ? 150.323 189.360 174.168 1.00 62.03  ? 285 ALA A O   1 
ATOM   1993  C CB  . ALA A 1 264 ? 152.421 190.982 172.628 1.00 62.03  ? 285 ALA A CB  1 
ATOM   1994  N N   . VAL A 1 265 ? 150.480 188.237 172.214 1.00 50.37  ? 286 VAL A N   1 
ATOM   1995  C CA  . VAL A 1 265 ? 150.055 186.946 172.739 1.00 50.37  ? 286 VAL A CA  1 
ATOM   1996  C C   . VAL A 1 265 ? 151.176 185.943 172.504 1.00 50.37  ? 286 VAL A C   1 
ATOM   1997  O O   . VAL A 1 265 ? 151.653 185.794 171.374 1.00 50.37  ? 286 VAL A O   1 
ATOM   1998  C CB  . VAL A 1 265 ? 148.745 186.472 172.081 1.00 50.37  ? 286 VAL A CB  1 
ATOM   1999  C CG1 . VAL A 1 265 ? 148.405 185.053 172.511 1.00 50.37  ? 286 VAL A CG1 1 
ATOM   2000  C CG2 . VAL A 1 265 ? 147.601 187.417 172.421 1.00 50.37  ? 286 VAL A CG2 1 
ATOM   2001  N N   . ILE A 1 266 ? 151.602 185.270 173.570 1.00 35.81  ? 287 ILE A N   1 
ATOM   2002  C CA  . ILE A 1 266 ? 152.593 184.205 173.475 1.00 35.81  ? 287 ILE A CA  1 
ATOM   2003  C C   . ILE A 1 266 ? 151.861 182.879 173.324 1.00 35.81  ? 287 ILE A C   1 
ATOM   2004  O O   . ILE A 1 266 ? 151.013 182.529 174.154 1.00 35.81  ? 287 ILE A O   1 
ATOM   2005  C CB  . ILE A 1 266 ? 153.510 184.195 174.708 1.00 35.81  ? 287 ILE A CB  1 
ATOM   2006  C CG1 . ILE A 1 266 ? 154.055 185.598 174.978 1.00 35.81  ? 287 ILE A CG1 1 
ATOM   2007  C CG2 . ILE A 1 266 ? 154.647 183.203 174.522 1.00 35.81  ? 287 ILE A CG2 1 
ATOM   2008  C CD1 . ILE A 1 266 ? 154.939 186.136 173.872 1.00 35.81  ? 287 ILE A CD1 1 
ATOM   2009  N N   . GLN A 1 267 ? 152.189 182.137 172.271 1.00 36.88  ? 288 GLN A N   1 
ATOM   2010  C CA  . GLN A 1 267 ? 151.517 180.891 171.935 1.00 36.88  ? 288 GLN A CA  1 
ATOM   2011  C C   . GLN A 1 267 ? 152.514 179.746 172.013 1.00 36.88  ? 288 GLN A C   1 
ATOM   2012  O O   . GLN A 1 267 ? 153.565 179.791 171.363 1.00 36.88  ? 288 GLN A O   1 
ATOM   2013  C CB  . GLN A 1 267 ? 150.925 180.962 170.526 1.00 36.88  ? 288 GLN A CB  1 
ATOM   2014  C CG  . GLN A 1 267 ? 149.877 179.911 170.221 1.00 36.88  ? 288 GLN A CG  1 
ATOM   2015  C CD  . GLN A 1 267 ? 148.681 180.005 171.142 1.00 36.88  ? 288 GLN A CD  1 
ATOM   2016  O OE1 . GLN A 1 267 ? 148.296 179.030 171.785 1.00 36.88  ? 288 GLN A OE1 1 
ATOM   2017  N NE2 . GLN A 1 267 ? 148.073 181.182 171.194 1.00 36.88  ? 288 GLN A NE2 1 
ATOM   2018  N N   . GLU A 1 268 ? 152.183 178.723 172.796 1.00 40.48  ? 289 GLU A N   1 
ATOM   2019  C CA  . GLU A 1 268 ? 152.940 177.481 172.799 1.00 40.48  ? 289 GLU A CA  1 
ATOM   2020  C C   . GLU A 1 268 ? 152.330 176.481 171.825 1.00 40.48  ? 289 GLU A C   1 
ATOM   2021  O O   . GLU A 1 268 ? 151.234 176.671 171.292 1.00 40.48  ? 289 GLU A O   1 
ATOM   2022  C CB  . GLU A 1 268 ? 153.019 176.861 174.201 1.00 40.48  ? 289 GLU A CB  1 
ATOM   2023  C CG  . GLU A 1 268 ? 153.849 177.634 175.219 1.00 40.48  ? 289 GLU A CG  1 
ATOM   2024  C CD  . GLU A 1 268 ? 153.091 178.754 175.893 1.00 40.48  ? 289 GLU A CD  1 
ATOM   2025  O OE1 . GLU A 1 268 ? 151.887 178.904 175.622 1.00 40.48  ? 289 GLU A OE1 1 
ATOM   2026  O OE2 . GLU A 1 268 ? 153.701 179.477 176.703 1.00 40.48  ? 289 GLU A OE2 1 
ATOM   2027  N N   . PHE A 1 269 ? 153.063 175.394 171.603 1.00 40.63  ? 290 PHE A N   1 
ATOM   2028  C CA  . PHE A 1 269 ? 152.652 174.353 170.677 1.00 40.63  ? 290 PHE A CA  1 
ATOM   2029  C C   . PHE A 1 269 ? 153.100 173.003 171.212 1.00 40.63  ? 290 PHE A C   1 
ATOM   2030  O O   . PHE A 1 269 ? 154.197 172.877 171.761 1.00 40.63  ? 290 PHE A O   1 
ATOM   2031  C CB  . PHE A 1 269 ? 153.241 174.591 169.283 1.00 40.63  ? 290 PHE A CB  1 
ATOM   2032  C CG  . PHE A 1 269 ? 152.537 175.662 168.509 1.00 40.63  ? 290 PHE A CG  1 
ATOM   2033  C CD1 . PHE A 1 269 ? 151.262 175.448 168.011 1.00 40.63  ? 290 PHE A CD1 1 
ATOM   2034  C CD2 . PHE A 1 269 ? 153.148 176.885 168.283 1.00 40.63  ? 290 PHE A CD2 1 
ATOM   2035  C CE1 . PHE A 1 269 ? 150.608 176.434 167.298 1.00 40.63  ? 290 PHE A CE1 1 
ATOM   2036  C CE2 . PHE A 1 269 ? 152.500 177.877 167.570 1.00 40.63  ? 290 PHE A CE2 1 
ATOM   2037  C CZ  . PHE A 1 269 ? 151.228 177.651 167.078 1.00 40.63  ? 290 PHE A CZ  1 
ATOM   2038  N N   . ILE A 1 270 ? 152.244 171.999 171.049 1.00 42.33  ? 291 ILE A N   1 
ATOM   2039  C CA  . ILE A 1 270 ? 152.542 170.627 171.436 1.00 42.33  ? 291 ILE A CA  1 
ATOM   2040  C C   . ILE A 1 270 ? 152.914 169.852 170.181 1.00 42.33  ? 291 ILE A C   1 
ATOM   2041  O O   . ILE A 1 270 ? 152.183 169.883 169.182 1.00 42.33  ? 291 ILE A O   1 
ATOM   2042  C CB  . ILE A 1 270 ? 151.345 169.978 172.151 1.00 42.33  ? 291 ILE A CB  1 
ATOM   2043  C CG1 . ILE A 1 270 ? 150.869 170.862 173.304 1.00 42.33  ? 291 ILE A CG1 1 
ATOM   2044  C CG2 . ILE A 1 270 ? 151.712 168.595 172.664 1.00 42.33  ? 291 ILE A CG2 1 
ATOM   2045  C CD1 . ILE A 1 270 ? 149.595 170.378 173.952 1.00 42.33  ? 291 ILE A CD1 1 
ATOM   2046  N N   . LYS A 1 271 ? 154.051 169.164 170.228 1.00 37.54  ? 292 LYS A N   1 
ATOM   2047  C CA  . LYS A 1 271 ? 154.574 168.423 169.089 1.00 37.54  ? 292 LYS A CA  1 
ATOM   2048  C C   . LYS A 1 271 ? 154.409 166.932 169.347 1.00 37.54  ? 292 LYS A C   1 
ATOM   2049  O O   . LYS A 1 271 ? 154.906 166.414 170.353 1.00 37.54  ? 292 LYS A O   1 
ATOM   2050  C CB  . LYS A 1 271 ? 156.043 168.766 168.846 1.00 37.54  ? 292 LYS A CB  1 
ATOM   2051  C CG  . LYS A 1 271 ? 156.279 170.202 168.413 1.00 37.54  ? 292 LYS A CG  1 
ATOM   2052  C CD  . LYS A 1 271 ? 157.731 170.433 168.029 1.00 37.54  ? 292 LYS A CD  1 
ATOM   2053  C CE  . LYS A 1 271 ? 158.629 170.440 169.255 1.00 37.54  ? 292 LYS A CE  1 
ATOM   2054  N NZ  . LYS A 1 271 ? 160.042 170.742 168.902 1.00 37.54  ? 292 LYS A NZ  1 
ATOM   2055  N N   . ILE A 1 272 ? 153.714 166.249 168.440 1.00 41.85  ? 293 ILE A N   1 
ATOM   2056  C CA  . ILE A 1 272 ? 153.530 164.807 168.509 1.00 41.85  ? 293 ILE A CA  1 
ATOM   2057  C C   . ILE A 1 272 ? 154.200 164.177 167.296 1.00 41.85  ? 293 ILE A C   1 
ATOM   2058  O O   . ILE A 1 272 ? 154.514 164.846 166.308 1.00 41.85  ? 293 ILE A O   1 
ATOM   2059  C CB  . ILE A 1 272 ? 152.042 164.404 168.579 1.00 41.85  ? 293 ILE A CB  1 
ATOM   2060  C CG1 . ILE A 1 272 ? 151.331 164.746 167.268 1.00 41.85  ? 293 ILE A CG1 1 
ATOM   2061  C CG2 . ILE A 1 272 ? 151.361 165.076 169.762 1.00 41.85  ? 293 ILE A CG2 1 
ATOM   2062  C CD1 . ILE A 1 272 ? 149.854 164.416 167.266 1.00 41.85  ? 293 ILE A CD1 1 
ATOM   2063  N N   . GLY A 1 273 ? 154.426 162.872 167.385 1.00 45.92  ? 294 GLY A N   1 
ATOM   2064  C CA  . GLY A 1 273 ? 155.070 162.123 166.320 1.00 45.92  ? 294 GLY A CA  1 
ATOM   2065  C C   . GLY A 1 273 ? 154.044 161.424 165.446 1.00 45.92  ? 294 GLY A C   1 
ATOM   2066  O O   . GLY A 1 273 ? 153.073 160.855 165.943 1.00 45.92  ? 294 GLY A O   1 
ATOM   2067  N N   . TYR A 1 274 ? 154.273 161.475 164.137 1.00 53.01  ? 295 TYR A N   1 
ATOM   2068  C CA  . TYR A 1 274 ? 153.395 160.845 163.166 1.00 53.01  ? 295 TYR A CA  1 
ATOM   2069  C C   . TYR A 1 274 ? 154.161 159.791 162.378 1.00 53.01  ? 295 TYR A C   1 
ATOM   2070  O O   . TYR A 1 274 ? 155.363 159.925 162.125 1.00 53.01  ? 295 TYR A O   1 
ATOM   2071  C CB  . TYR A 1 274 ? 152.763 161.880 162.216 1.00 53.01  ? 295 TYR A CB  1 
ATOM   2072  C CG  . TYR A 1 274 ? 153.726 162.634 161.321 1.00 53.01  ? 295 TYR A CG  1 
ATOM   2073  C CD1 . TYR A 1 274 ? 154.403 163.757 161.785 1.00 53.01  ? 295 TYR A CD1 1 
ATOM   2074  C CD2 . TYR A 1 274 ? 153.931 162.243 160.002 1.00 53.01  ? 295 TYR A CD2 1 
ATOM   2075  C CE1 . TYR A 1 274 ? 155.276 164.454 160.968 1.00 53.01  ? 295 TYR A CE1 1 
ATOM   2076  C CE2 . TYR A 1 274 ? 154.801 162.934 159.178 1.00 53.01  ? 295 TYR A CE2 1 
ATOM   2077  C CZ  . TYR A 1 274 ? 155.468 164.038 159.666 1.00 53.01  ? 295 TYR A CZ  1 
ATOM   2078  O OH  . TYR A 1 274 ? 156.333 164.728 158.848 1.00 53.01  ? 295 TYR A OH  1 
ATOM   2079  N N   . ASN A 1 275 ? 153.447 158.733 162.001 1.00 58.43  ? 296 ASN A N   1 
ATOM   2080  C CA  . ASN A 1 275 ? 154.033 157.597 161.300 1.00 58.43  ? 296 ASN A CA  1 
ATOM   2081  C C   . ASN A 1 275 ? 153.849 157.796 159.800 1.00 58.43  ? 296 ASN A C   1 
ATOM   2082  O O   . ASN A 1 275 ? 152.733 157.686 159.283 1.00 58.43  ? 296 ASN A O   1 
ATOM   2083  C CB  . ASN A 1 275 ? 153.388 156.295 161.767 1.00 58.43  ? 296 ASN A CB  1 
ATOM   2084  C CG  . ASN A 1 275 ? 154.226 155.075 161.441 1.00 58.43  ? 296 ASN A CG  1 
ATOM   2085  O OD1 . ASN A 1 275 ? 155.284 155.180 160.822 1.00 58.43  ? 296 ASN A OD1 1 
ATOM   2086  N ND2 . ASN A 1 275 ? 153.755 153.907 161.860 1.00 58.43  ? 296 ASN A ND2 1 
ATOM   2087  N N   . PHE A 1 276 ? 154.945 158.087 159.103 1.00 66.99  ? 297 PHE A N   1 
ATOM   2088  C CA  . PHE A 1 276 ? 154.922 158.276 157.661 1.00 66.99  ? 297 PHE A CA  1 
ATOM   2089  C C   . PHE A 1 276 ? 156.123 157.575 157.048 1.00 66.99  ? 297 PHE A C   1 
ATOM   2090  O O   . PHE A 1 276 ? 157.222 157.602 157.613 1.00 66.99  ? 297 PHE A O   1 
ATOM   2091  C CB  . PHE A 1 276 ? 154.932 159.764 157.291 1.00 66.99  ? 297 PHE A CB  1 
ATOM   2092  C CG  . PHE A 1 276 ? 154.809 160.022 155.817 1.00 66.99  ? 297 PHE A CG  1 
ATOM   2093  C CD1 . PHE A 1 276 ? 153.593 159.855 155.171 1.00 66.99  ? 297 PHE A CD1 1 
ATOM   2094  C CD2 . PHE A 1 276 ? 155.907 160.434 155.078 1.00 66.99  ? 297 PHE A CD2 1 
ATOM   2095  C CE1 . PHE A 1 276 ? 153.474 160.094 153.812 1.00 66.99  ? 297 PHE A CE1 1 
ATOM   2096  C CE2 . PHE A 1 276 ? 155.797 160.676 153.720 1.00 66.99  ? 297 PHE A CE2 1 
ATOM   2097  C CZ  . PHE A 1 276 ? 154.579 160.505 153.086 1.00 66.99  ? 297 PHE A CZ  1 
ATOM   2098  N N   . GLY A 1 277 ? 155.899 156.931 155.902 1.00 69.45  ? 298 GLY A N   1 
ATOM   2099  C CA  . GLY A 1 277 ? 156.960 156.262 155.171 1.00 69.45  ? 298 GLY A CA  1 
ATOM   2100  C C   . GLY A 1 277 ? 157.582 155.085 155.884 1.00 69.45  ? 298 GLY A C   1 
ATOM   2101  O O   . GLY A 1 277 ? 158.718 154.715 155.578 1.00 69.45  ? 298 GLY A O   1 
ATOM   2102  N N   . GLY A 1 278 ? 156.869 154.482 156.832 1.00 64.96  ? 299 GLY A N   1 
ATOM   2103  C CA  . GLY A 1 278 ? 157.465 153.465 157.671 1.00 64.96  ? 299 GLY A CA  1 
ATOM   2104  C C   . GLY A 1 278 ? 158.411 153.997 158.721 1.00 64.96  ? 299 GLY A C   1 
ATOM   2105  O O   . GLY A 1 278 ? 159.226 153.235 159.247 1.00 64.96  ? 299 GLY A O   1 
ATOM   2106  N N   . SER A 1 279 ? 158.331 155.287 159.046 1.00 63.25  ? 300 SER A N   1 
ATOM   2107  C CA  . SER A 1 279 ? 159.208 155.879 160.045 1.00 63.25  ? 300 SER A CA  1 
ATOM   2108  C C   . SER A 1 279 ? 158.424 156.874 160.888 1.00 63.25  ? 300 SER A C   1 
ATOM   2109  O O   . SER A 1 279 ? 157.317 157.286 160.534 1.00 63.25  ? 300 SER A O   1 
ATOM   2110  C CB  . SER A 1 279 ? 160.419 156.563 159.399 1.00 63.25  ? 300 SER A CB  1 
ATOM   2111  O OG  . SER A 1 279 ? 161.247 157.157 160.382 1.00 63.25  ? 300 SER A OG  1 
ATOM   2112  N N   . LEU A 1 280 ? 159.007 157.252 162.021 1.00 57.60  ? 301 LEU A N   1 
ATOM   2113  C CA  . LEU A 1 280 ? 158.379 158.184 162.948 1.00 57.60  ? 301 LEU A CA  1 
ATOM   2114  C C   . LEU A 1 280 ? 159.015 159.558 162.796 1.00 57.60  ? 301 LEU A C   1 
ATOM   2115  O O   . LEU A 1 280 ? 160.238 159.701 162.920 1.00 57.60  ? 301 LEU A O   1 
ATOM   2116  C CB  . LEU A 1 280 ? 158.512 157.689 164.389 1.00 57.60  ? 301 LEU A CB  1 
ATOM   2117  C CG  . LEU A 1 280 ? 157.450 158.150 165.387 1.00 57.60  ? 301 LEU A CG  1 
ATOM   2118  C CD1 . LEU A 1 280 ? 156.053 157.920 164.834 1.00 57.60  ? 301 LEU A CD1 1 
ATOM   2119  C CD2 . LEU A 1 280 ? 157.627 157.437 166.717 1.00 57.60  ? 301 LEU A CD2 1 
ATOM   2120  N N   . TRP A 1 281 ? 158.185 160.568 162.538 1.00 61.25  ? 302 TRP A N   1 
ATOM   2121  C CA  . TRP A 1 281 ? 158.660 161.910 162.244 1.00 61.25  ? 302 TRP A CA  1 
ATOM   2122  C C   . TRP A 1 281 ? 157.963 162.921 163.141 1.00 61.25  ? 302 TRP A C   1 
ATOM   2123  O O   . TRP A 1 281 ? 156.848 162.694 163.617 1.00 61.25  ? 302 TRP A O   1 
ATOM   2124  C CB  . TRP A 1 281 ? 158.417 162.297 160.776 1.00 61.25  ? 302 TRP A CB  1 
ATOM   2125  C CG  . TRP A 1 281 ? 158.905 161.302 159.766 1.00 61.25  ? 302 TRP A CG  1 
ATOM   2126  C CD1 . TRP A 1 281 ? 158.276 160.157 159.370 1.00 61.25  ? 302 TRP A CD1 1 
ATOM   2127  C CD2 . TRP A 1 281 ? 160.116 161.377 159.006 1.00 61.25  ? 302 TRP A CD2 1 
ATOM   2128  N NE1 . TRP A 1 281 ? 159.025 159.511 158.419 1.00 61.25  ? 302 TRP A NE1 1 
ATOM   2129  C CE2 . TRP A 1 281 ? 160.160 160.238 158.178 1.00 61.25  ? 302 TRP A CE2 1 
ATOM   2130  C CE3 . TRP A 1 281 ? 161.171 162.293 158.950 1.00 61.25  ? 302 TRP A CE3 1 
ATOM   2131  C CZ2 . TRP A 1 281 ? 161.217 159.991 157.304 1.00 61.25  ? 302 TRP A CZ2 1 
ATOM   2132  C CZ3 . TRP A 1 281 ? 162.219 162.046 158.081 1.00 61.25  ? 302 TRP A CZ3 1 
ATOM   2133  C CH2 . TRP A 1 281 ? 162.234 160.905 157.270 1.00 61.25  ? 302 TRP A CH2 1 
ATOM   2134  N N   . MET A 1 282 ? 158.642 164.043 163.367 1.00 59.12  ? 303 MET A N   1 
ATOM   2135  C CA  . MET A 1 282 ? 158.052 165.194 164.031 1.00 59.12  ? 303 MET A CA  1 
ATOM   2136  C C   . MET A 1 282 ? 158.268 166.439 163.183 1.00 59.12  ? 303 MET A C   1 
ATOM   2137  O O   . MET A 1 282 ? 159.315 166.574 162.538 1.00 59.12  ? 303 MET A O   1 
ATOM   2138  C CB  . MET A 1 282 ? 158.652 165.425 165.425 1.00 59.12  ? 303 MET A CB  1 
ATOM   2139  C CG  . MET A 1 282 ? 158.348 164.345 166.439 1.00 59.12  ? 303 MET A CG  1 
ATOM   2140  S SD  . MET A 1 282 ? 159.026 164.778 168.050 1.00 59.12  ? 303 MET A SD  1 
ATOM   2141  C CE  . MET A 1 282 ? 160.770 164.509 167.764 1.00 59.12  ? 303 MET A CE  1 
ATOM   2142  N N   . PRO A 1 283 ? 157.300 167.355 163.150 1.00 50.76  ? 304 PRO A N   1 
ATOM   2143  C CA  . PRO A 1 283 ? 157.520 168.630 162.461 1.00 50.76  ? 304 PRO A CA  1 
ATOM   2144  C C   . PRO A 1 283 ? 158.527 169.496 163.200 1.00 50.76  ? 304 PRO A C   1 
ATOM   2145  O O   . PRO A 1 283 ? 158.639 169.455 164.427 1.00 50.76  ? 304 PRO A O   1 
ATOM   2146  C CB  . PRO A 1 283 ? 156.130 169.277 162.452 1.00 50.76  ? 304 PRO A CB  1 
ATOM   2147  C CG  . PRO A 1 283 ? 155.401 168.630 163.574 1.00 50.76  ? 304 PRO A CG  1 
ATOM   2148  C CD  . PRO A 1 283 ? 155.923 167.229 163.657 1.00 50.76  ? 304 PRO A CD  1 
ATOM   2149  N N   . THR A 1 284 ? 159.267 170.292 162.428 1.00 57.46  ? 305 THR A N   1 
ATOM   2150  C CA  . THR A 1 284 ? 160.314 171.155 162.972 1.00 57.46  ? 305 THR A CA  1 
ATOM   2151  C C   . THR A 1 284 ? 159.775 172.580 163.057 1.00 57.46  ? 305 THR A C   1 
ATOM   2152  O O   . THR A 1 284 ? 159.961 173.406 162.164 1.00 57.46  ? 305 THR A O   1 
ATOM   2153  C CB  . THR A 1 284 ? 161.574 171.077 162.116 1.00 57.46  ? 305 THR A CB  1 
ATOM   2154  O OG1 . THR A 1 284 ? 161.291 171.576 160.803 1.00 57.46  ? 305 THR A OG1 1 
ATOM   2155  C CG2 . THR A 1 284 ? 162.057 169.641 162.013 1.00 57.46  ? 305 THR A CG2 1 
ATOM   2156  N N   . ILE A 1 285 ? 159.094 172.863 164.163 1.00 48.63  ? 306 ILE A N   1 
ATOM   2157  C CA  . ILE A 1 285 ? 158.545 174.192 164.422 1.00 48.63  ? 306 ILE A CA  1 
ATOM   2158  C C   . ILE A 1 285 ? 159.019 174.651 165.797 1.00 48.63  ? 306 ILE A C   1 
ATOM   2159  O O   . ILE A 1 285 ? 159.250 173.811 166.680 1.00 48.63  ? 306 ILE A O   1 
ATOM   2160  C CB  . ILE A 1 285 ? 157.009 174.192 164.327 1.00 48.63  ? 306 ILE A CB  1 
ATOM   2161  C CG1 . ILE A 1 285 ? 156.414 173.051 165.156 1.00 48.63  ? 306 ILE A CG1 1 
ATOM   2162  C CG2 . ILE A 1 285 ? 156.556 174.103 162.877 1.00 48.63  ? 306 ILE A CG2 1 
ATOM   2163  C CD1 . ILE A 1 285 ? 154.911 173.122 165.297 1.00 48.63  ? 306 ILE A CD1 1 
ATOM   2164  N N   . PRO A 1 286 ? 159.212 175.951 166.017 1.00 48.51  ? 307 PRO A N   1 
ATOM   2165  C CA  . PRO A 1 286 ? 159.538 176.425 167.366 1.00 48.51  ? 307 PRO A CA  1 
ATOM   2166  C C   . PRO A 1 286 ? 158.343 176.309 168.297 1.00 48.51  ? 307 PRO A C   1 
ATOM   2167  O O   . PRO A 1 286 ? 157.187 176.311 167.868 1.00 48.51  ? 307 PRO A O   1 
ATOM   2168  C CB  . PRO A 1 286 ? 159.930 177.890 167.146 1.00 48.51  ? 307 PRO A CB  1 
ATOM   2169  C CG  . PRO A 1 286 ? 159.269 178.268 165.867 1.00 48.51  ? 307 PRO A CG  1 
ATOM   2170  C CD  . PRO A 1 286 ? 159.285 177.034 165.022 1.00 48.51  ? 307 PRO A CD  1 
ATOM   2171  N N   . ASN A 1 287 ? 158.640 176.194 169.592 1.00 45.82  ? 308 ASN A N   1 
ATOM   2172  C CA  . ASN A 1 287 ? 157.578 176.049 170.581 1.00 45.82  ? 308 ASN A CA  1 
ATOM   2173  C C   . ASN A 1 287 ? 156.826 177.358 170.790 1.00 45.82  ? 308 ASN A C   1 
ATOM   2174  O O   . ASN A 1 287 ? 155.591 177.369 170.826 1.00 45.82  ? 308 ASN A O   1 
ATOM   2175  C CB  . ASN A 1 287 ? 158.157 175.548 171.903 1.00 45.82  ? 308 ASN A CB  1 
ATOM   2176  C CG  . ASN A 1 287 ? 158.752 174.159 171.790 1.00 45.82  ? 308 ASN A CG  1 
ATOM   2177  O OD1 . ASN A 1 287 ? 158.041 173.185 171.548 1.00 45.82  ? 308 ASN A OD1 1 
ATOM   2178  N ND2 . ASN A 1 287 ? 160.064 174.062 171.968 1.00 45.82  ? 308 ASN A ND2 1 
ATOM   2179  N N   . LYS A 1 288 ? 157.545 178.470 170.902 1.00 51.18  ? 309 LYS A N   1 
ATOM   2180  C CA  . LYS A 1 288 ? 156.972 179.747 171.305 1.00 51.18  ? 309 LYS A CA  1 
ATOM   2181  C C   . LYS A 1 288 ? 156.845 180.669 170.102 1.00 51.18  ? 309 LYS A C   1 
ATOM   2182  O O   . LYS A 1 288 ? 157.806 180.850 169.348 1.00 51.18  ? 309 LYS A O   1 
ATOM   2183  C CB  . LYS A 1 288 ? 157.837 180.403 172.381 1.00 51.18  ? 309 LYS A CB  1 
ATOM   2184  C CG  . LYS A 1 288 ? 157.810 179.677 173.711 1.00 51.18  ? 309 LYS A CG  1 
ATOM   2185  C CD  . LYS A 1 288 ? 158.905 180.183 174.630 1.00 51.18  ? 309 LYS A CD  1 
ATOM   2186  C CE  . LYS A 1 288 ? 160.278 179.917 174.035 1.00 51.18  ? 309 LYS A CE  1 
ATOM   2187  N NZ  . LYS A 1 288 ? 160.579 178.461 173.963 1.00 51.18  ? 309 LYS A NZ  1 
ATOM   2188  N N   . ILE A 1 289 ? 155.657 181.244 169.922 1.00 55.11  ? 310 ILE A N   1 
ATOM   2189  C CA  . ILE A 1 289 ? 155.387 182.200 168.852 1.00 55.11  ? 310 ILE A CA  1 
ATOM   2190  C C   . ILE A 1 289 ? 154.742 183.431 169.473 1.00 55.11  ? 310 ILE A C   1 
ATOM   2191  O O   . ILE A 1 289 ? 153.716 183.319 170.152 1.00 55.11  ? 310 ILE A O   1 
ATOM   2192  C CB  . ILE A 1 289 ? 154.476 181.606 167.764 1.00 55.11  ? 310 ILE A CB  1 
ATOM   2193  C CG1 . ILE A 1 289 ? 155.200 180.495 167.005 1.00 55.11  ? 310 ILE A CG1 1 
ATOM   2194  C CG2 . ILE A 1 289 ? 153.993 182.683 166.803 1.00 55.11  ? 310 ILE A CG2 1 
ATOM   2195  C CD1 . ILE A 1 289 ? 156.409 180.973 166.235 1.00 55.11  ? 310 ILE A CD1 1 
ATOM   2196  N N   . ILE A 1 290 ? 155.331 184.598 169.244 1.00 62.19  ? 311 ILE A N   1 
ATOM   2197  C CA  . ILE A 1 290 ? 154.749 185.852 169.705 1.00 62.19  ? 311 ILE A CA  1 
ATOM   2198  C C   . ILE A 1 290 ? 153.948 186.474 168.566 1.00 62.19  ? 311 ILE A C   1 
ATOM   2199  O O   . ILE A 1 290 ? 154.459 186.659 167.454 1.00 62.19  ? 311 ILE A O   1 
ATOM   2200  C CB  . ILE A 1 290 ? 155.836 186.805 170.240 1.00 62.19  ? 311 ILE A CB  1 
ATOM   2201  C CG1 . ILE A 1 290 ? 155.275 188.211 170.470 1.00 62.19  ? 311 ILE A CG1 1 
ATOM   2202  C CG2 . ILE A 1 290 ? 157.088 186.790 169.367 1.00 62.19  ? 311 ILE A CG2 1 
ATOM   2203  C CD1 . ILE A 1 290 ? 156.211 189.114 171.244 1.00 62.19  ? 311 ILE A CD1 1 
ATOM   2204  N N   . ILE A 1 291 ? 152.675 186.762 168.830 1.00 71.48  ? 312 ILE A N   1 
ATOM   2205  C CA  . ILE A 1 291 ? 151.753 187.289 167.832 1.00 71.48  ? 312 ILE A CA  1 
ATOM   2206  C C   . ILE A 1 291 ? 151.320 188.677 168.276 1.00 71.48  ? 312 ILE A C   1 
ATOM   2207  O O   . ILE A 1 291 ? 150.849 188.852 169.406 1.00 71.48  ? 312 ILE A O   1 
ATOM   2208  C CB  . ILE A 1 291 ? 150.533 186.368 167.647 1.00 71.48  ? 312 ILE A CB  1 
ATOM   2209  C CG1 . ILE A 1 291 ? 150.982 184.956 167.270 1.00 71.48  ? 312 ILE A CG1 1 
ATOM   2210  C CG2 . ILE A 1 291 ? 149.594 186.925 166.588 1.00 71.48  ? 312 ILE A CG2 1 
ATOM   2211  C CD1 . ILE A 1 291 ? 149.860 183.944 167.250 1.00 71.48  ? 312 ILE A CD1 1 
ATOM   2212  N N   . ARG A 1 292 ? 151.477 189.662 167.390 1.00 90.69  ? 313 ARG A N   1 
ATOM   2213  C CA  . ARG A 1 292 ? 151.131 191.043 167.731 1.00 90.69  ? 313 ARG A CA  1 
ATOM   2214  C C   . ARG A 1 292 ? 150.617 191.725 166.460 1.00 90.69  ? 313 ARG A C   1 
ATOM   2215  O O   . ARG A 1 292 ? 151.398 192.252 165.665 1.00 90.69  ? 313 ARG A O   1 
ATOM   2216  C CB  . ARG A 1 292 ? 152.328 191.773 168.327 1.00 90.69  ? 313 ARG A CB  1 
ATOM   2217  C CG  . ARG A 1 292 ? 152.080 193.228 168.706 1.00 90.69  ? 313 ARG A CG  1 
ATOM   2218  C CD  . ARG A 1 292 ? 153.305 193.883 169.352 1.00 90.69  ? 313 ARG A CD  1 
ATOM   2219  N NE  . ARG A 1 292 ? 154.510 193.805 168.532 1.00 90.69  ? 313 ARG A NE  1 
ATOM   2220  C CZ  . ARG A 1 292 ? 155.552 193.027 168.795 1.00 90.69  ? 313 ARG A CZ  1 
ATOM   2221  N NH1 . ARG A 1 292 ? 155.576 192.240 169.858 1.00 90.69  ? 313 ARG A NH1 1 
ATOM   2222  N NH2 . ARG A 1 292 ? 156.597 193.040 167.972 1.00 90.69  ? 313 ARG A NH2 1 
ATOM   2223  N N   . GLY A 1 293 ? 149.293 191.705 166.291 1.00 110.40 ? 314 GLY A N   1 
ATOM   2224  C CA  . GLY A 1 293 ? 148.621 192.380 165.193 1.00 110.40 ? 314 GLY A CA  1 
ATOM   2225  C C   . GLY A 1 293 ? 148.994 191.865 163.819 1.00 110.40 ? 314 GLY A C   1 
ATOM   2226  O O   . GLY A 1 293 ? 149.238 192.663 162.906 1.00 110.40 ? 314 GLY A O   1 
ATOM   2227  N N   . TYR A 1 294 ? 149.028 190.536 163.683 1.00 115.46 ? 315 TYR A N   1 
ATOM   2228  C CA  . TYR A 1 294 ? 149.556 189.818 162.518 1.00 115.46 ? 315 TYR A CA  1 
ATOM   2229  C C   . TYR A 1 294 ? 150.995 190.263 162.232 1.00 115.46 ? 315 TYR A C   1 
ATOM   2230  O O   . TYR A 1 294 ? 151.299 190.957 161.261 1.00 115.46 ? 315 TYR A O   1 
ATOM   2231  C CB  . TYR A 1 294 ? 148.624 189.963 161.300 1.00 115.46 ? 315 TYR A CB  1 
ATOM   2232  C CG  . TYR A 1 294 ? 149.046 189.201 160.058 1.00 115.46 ? 315 TYR A CG  1 
ATOM   2233  C CD1 . TYR A 1 294 ? 148.900 187.820 159.987 1.00 115.46 ? 315 TYR A CD1 1 
ATOM   2234  C CD2 . TYR A 1 294 ? 149.523 189.869 158.934 1.00 115.46 ? 315 TYR A CD2 1 
ATOM   2235  C CE1 . TYR A 1 294 ? 149.272 187.119 158.852 1.00 115.46 ? 315 TYR A CE1 1 
ATOM   2236  C CE2 . TYR A 1 294 ? 149.898 189.179 157.798 1.00 115.46 ? 315 TYR A CE2 1 
ATOM   2237  C CZ  . TYR A 1 294 ? 149.766 187.806 157.761 1.00 115.46 ? 315 TYR A CZ  1 
ATOM   2238  O OH  . TYR A 1 294 ? 150.132 187.123 156.626 1.00 115.46 ? 315 TYR A OH  1 
ATOM   2239  N N   . HIS A 1 295 ? 151.876 189.901 163.166 1.00 95.93  ? 316 HIS A N   1 
ATOM   2240  C CA  . HIS A 1 295 ? 153.317 190.101 163.013 1.00 95.93  ? 316 HIS A CA  1 
ATOM   2241  C C   . HIS A 1 295 ? 153.991 189.041 163.877 1.00 95.93  ? 316 HIS A C   1 
ATOM   2242  O O   . HIS A 1 295 ? 154.062 189.192 165.100 1.00 95.93  ? 316 HIS A O   1 
ATOM   2243  C CB  . HIS A 1 295 ? 153.743 191.506 163.418 1.00 95.93  ? 316 HIS A CB  1 
ATOM   2244  C CG  . HIS A 1 295 ? 155.063 191.922 162.849 1.00 95.93  ? 316 HIS A CG  1 
ATOM   2245  N ND1 . HIS A 1 295 ? 155.552 193.205 162.960 1.00 95.93  ? 316 HIS A ND1 1 
ATOM   2246  C CD2 . HIS A 1 295 ? 156.000 191.221 162.167 1.00 95.93  ? 316 HIS A CD2 1 
ATOM   2247  C CE1 . HIS A 1 295 ? 156.731 193.278 162.369 1.00 95.93  ? 316 HIS A CE1 1 
ATOM   2248  N NE2 . HIS A 1 295 ? 157.026 192.087 161.880 1.00 95.93  ? 316 HIS A NE2 1 
ATOM   2249  N N   . LEU A 1 296 ? 154.470 187.978 163.241 1.00 76.67  ? 317 LEU A N   1 
ATOM   2250  C CA  . LEU A 1 296 ? 155.055 186.856 163.957 1.00 76.67  ? 317 LEU A CA  1 
ATOM   2251  C C   . LEU A 1 296 ? 156.555 187.050 164.125 1.00 76.67  ? 317 LEU A C   1 
ATOM   2252  O O   . LEU A 1 296 ? 157.247 187.481 163.199 1.00 76.67  ? 317 LEU A O   1 
ATOM   2253  C CB  . LEU A 1 296 ? 154.780 185.542 163.224 1.00 76.67  ? 317 LEU A CB  1 
ATOM   2254  C CG  . LEU A 1 296 ? 153.375 185.292 162.680 1.00 76.67  ? 317 LEU A CG  1 
ATOM   2255  C CD1 . LEU A 1 296 ? 153.326 183.961 161.945 1.00 76.67  ? 317 LEU A CD1 1 
ATOM   2256  C CD2 . LEU A 1 296 ? 152.356 185.326 163.801 1.00 76.67  ? 317 LEU A CD2 1 
ATOM   2257  N N   . SER A 1 297 ? 157.052 186.724 165.317 1.00 64.77  ? 318 SER A N   1 
ATOM   2258  C CA  . SER A 1 297 ? 158.470 186.811 165.630 1.00 64.77  ? 318 SER A CA  1 
ATOM   2259  C C   . SER A 1 297 ? 158.845 185.622 166.504 1.00 64.77  ? 318 SER A C   1 
ATOM   2260  O O   . SER A 1 297 ? 158.014 184.761 166.808 1.00 64.77  ? 318 SER A O   1 
ATOM   2261  C CB  . SER A 1 297 ? 158.806 188.138 166.320 1.00 64.77  ? 318 SER A CB  1 
ATOM   2262  O OG  . SER A 1 297 ? 158.504 189.239 165.481 1.00 64.77  ? 318 SER A OG  1 
ATOM   2263  N N   . LEU A 1 298 ? 160.109 185.575 166.915 1.00 55.48  ? 319 LEU A N   1 
ATOM   2264  C CA  . LEU A 1 298 ? 160.618 184.512 167.769 1.00 55.48  ? 319 LEU A CA  1 
ATOM   2265  C C   . LEU A 1 298 ? 161.209 185.104 169.039 1.00 55.48  ? 319 LEU A C   1 
ATOM   2266  O O   . LEU A 1 298 ? 161.846 186.161 169.006 1.00 55.48  ? 319 LEU A O   1 
ATOM   2267  C CB  . LEU A 1 298 ? 161.678 183.678 167.047 1.00 55.48  ? 319 LEU A CB  1 
ATOM   2268  C CG  . LEU A 1 298 ? 161.183 182.869 165.851 1.00 55.48  ? 319 LEU A CG  1 
ATOM   2269  C CD1 . LEU A 1 298 ? 162.337 182.141 165.180 1.00 55.48  ? 319 LEU A CD1 1 
ATOM   2270  C CD2 . LEU A 1 298 ? 160.107 181.895 166.286 1.00 55.48  ? 319 LEU A CD2 1 
ATOM   2271  N N   . ILE A 1 299 ? 160.995 184.416 170.158 1.00 46.78  ? 320 ILE A N   1 
ATOM   2272  C CA  . ILE A 1 299 ? 161.581 184.794 171.436 1.00 46.78  ? 320 ILE A CA  1 
ATOM   2273  C C   . ILE A 1 299 ? 162.305 183.586 172.007 1.00 46.78  ? 320 ILE A C   1 
ATOM   2274  O O   . ILE A 1 299 ? 161.974 182.437 171.701 1.00 46.78  ? 320 ILE A O   1 
ATOM   2275  C CB  . ILE A 1 299 ? 160.525 185.316 172.438 1.00 46.78  ? 320 ILE A CB  1 
ATOM   2276  C CG1 . ILE A 1 299 ? 159.369 184.326 172.563 1.00 46.78  ? 320 ILE A CG1 1 
ATOM   2277  C CG2 . ILE A 1 299 ? 160.010 186.682 172.020 1.00 46.78  ? 320 ILE A CG2 1 
ATOM   2278  C CD1 . ILE A 1 299 ? 158.417 184.650 173.686 1.00 46.78  ? 320 ILE A CD1 1 
ATOM   2279  N N   . ASP A 1 300 ? 163.308 183.853 172.839 1.00 53.05  ? 321 ASP A N   1 
ATOM   2280  C CA  . ASP A 1 300 ? 164.054 182.809 173.530 1.00 53.05  ? 321 ASP A CA  1 
ATOM   2281  C C   . ASP A 1 300 ? 163.803 182.942 175.025 1.00 53.05  ? 321 ASP A C   1 
ATOM   2282  O O   . ASP A 1 300 ? 164.036 184.006 175.609 1.00 53.05  ? 321 ASP A O   1 
ATOM   2283  C CB  . ASP A 1 300 ? 165.549 182.885 173.201 1.00 53.05  ? 321 ASP A CB  1 
ATOM   2284  C CG  . ASP A 1 300 ? 166.114 184.285 173.345 1.00 53.05  ? 321 ASP A CG  1 
ATOM   2285  O OD1 . ASP A 1 300 ? 165.358 185.255 173.132 1.00 53.05  ? 321 ASP A OD1 1 
ATOM   2286  O OD2 . ASP A 1 300 ? 167.313 184.415 173.670 1.00 53.05  ? 321 ASP A OD2 1 
ATOM   2287  N N   . SER A 1 301 ? 163.309 181.871 175.636 1.00 54.43  ? 322 SER A N   1 
ATOM   2288  C CA  . SER A 1 301 ? 163.007 181.864 177.066 1.00 54.43  ? 322 SER A CA  1 
ATOM   2289  C C   . SER A 1 301 ? 164.179 181.284 177.856 1.00 54.43  ? 322 SER A C   1 
ATOM   2290  O O   . SER A 1 301 ? 164.052 180.313 178.602 1.00 54.43  ? 322 SER A O   1 
ATOM   2291  C CB  . SER A 1 301 ? 161.719 181.090 177.328 1.00 54.43  ? 322 SER A CB  1 
ATOM   2292  O OG  . SER A 1 301 ? 161.895 179.707 177.079 1.00 54.43  ? 322 SER A OG  1 
ATOM   2293  N N   . THR A 1 302 ? 165.344 181.906 177.675 1.00 57.40  ? 323 THR A N   1 
ATOM   2294  C CA  . THR A 1 302 ? 166.551 181.498 178.378 1.00 57.40  ? 323 THR A CA  1 
ATOM   2295  C C   . THR A 1 302 ? 166.803 182.298 179.647 1.00 57.40  ? 323 THR A C   1 
ATOM   2296  O O   . THR A 1 302 ? 167.518 181.816 180.532 1.00 57.40  ? 323 THR A O   1 
ATOM   2297  C CB  . THR A 1 302 ? 167.771 181.626 177.459 1.00 57.40  ? 323 THR A CB  1 
ATOM   2298  O OG1 . THR A 1 302 ? 168.074 183.011 177.256 1.00 57.40  ? 323 THR A OG1 1 
ATOM   2299  C CG2 . THR A 1 302 ? 167.492 180.973 176.115 1.00 57.40  ? 323 THR A CG2 1 
ATOM   2300  N N   . ASN A 1 303 ? 166.236 183.500 179.755 1.00 59.15  ? 324 ASN A N   1 
ATOM   2301  C CA  . ASN A 1 303 ? 166.376 184.323 180.948 1.00 59.15  ? 324 ASN A CA  1 
ATOM   2302  C C   . ASN A 1 303 ? 165.031 184.808 181.472 1.00 59.15  ? 324 ASN A C   1 
ATOM   2303  O O   . ASN A 1 303 ? 164.999 185.684 182.344 1.00 59.15  ? 324 ASN A O   1 
ATOM   2304  C CB  . ASN A 1 303 ? 167.287 185.525 180.671 1.00 59.15  ? 324 ASN A CB  1 
ATOM   2305  C CG  . ASN A 1 303 ? 168.665 185.113 180.193 1.00 59.15  ? 324 ASN A CG  1 
ATOM   2306  O OD1 . ASN A 1 303 ? 169.063 185.422 179.070 1.00 59.15  ? 324 ASN A OD1 1 
ATOM   2307  N ND2 . ASN A 1 303 ? 169.400 184.408 181.045 1.00 59.15  ? 324 ASN A ND2 1 
ATOM   2308  N N   . CYS A 1 304 ? 163.927 184.267 180.967 1.00 45.64  ? 325 CYS A N   1 
ATOM   2309  C CA  . CYS A 1 304 ? 162.588 184.698 181.342 1.00 45.64  ? 325 CYS A CA  1 
ATOM   2310  C C   . CYS A 1 304 ? 161.906 183.606 182.153 1.00 45.64  ? 325 CYS A C   1 
ATOM   2311  O O   . CYS A 1 304 ? 161.895 182.440 181.747 1.00 45.64  ? 325 CYS A O   1 
ATOM   2312  C CB  . CYS A 1 304 ? 161.755 185.028 180.103 1.00 45.64  ? 325 CYS A CB  1 
ATOM   2313  S SG  . CYS A 1 304 ? 162.488 186.265 179.013 1.00 45.64  ? 325 CYS A SG  1 
ATOM   2314  N N   . ILE A 1 305 ? 161.340 183.987 183.291 1.00 35.80  ? 326 ILE A N   1 
ATOM   2315  C CA  . ILE A 1 305 ? 160.583 183.053 184.113 1.00 35.80  ? 326 ILE A CA  1 
ATOM   2316  C C   . ILE A 1 305 ? 159.172 182.933 183.558 1.00 35.80  ? 326 ILE A C   1 
ATOM   2317  O O   . ILE A 1 305 ? 158.565 183.924 183.134 1.00 35.80  ? 326 ILE A O   1 
ATOM   2318  C CB  . ILE A 1 305 ? 160.577 183.507 185.584 1.00 35.80  ? 326 ILE A CB  1 
ATOM   2319  C CG1 . ILE A 1 305 ? 160.370 185.018 185.682 1.00 35.80  ? 326 ILE A CG1 1 
ATOM   2320  C CG2 . ILE A 1 305 ? 161.872 183.105 186.271 1.00 35.80  ? 326 ILE A CG2 1 
ATOM   2321  C CD1 . ILE A 1 305 ? 160.142 185.506 187.091 1.00 35.80  ? 326 ILE A CD1 1 
ATOM   2322  N N   . ILE A 1 306 ? 158.647 181.712 183.549 1.00 31.31  ? 327 ILE A N   1 
ATOM   2323  C CA  . ILE A 1 306 ? 157.337 181.417 182.981 1.00 31.31  ? 327 ILE A CA  1 
ATOM   2324  C C   . ILE A 1 306 ? 156.359 181.203 184.125 1.00 31.31  ? 327 ILE A C   1 
ATOM   2325  O O   . ILE A 1 306 ? 156.518 180.271 184.923 1.00 31.31  ? 327 ILE A O   1 
ATOM   2326  C CB  . ILE A 1 306 ? 157.383 180.187 182.063 1.00 31.31  ? 327 ILE A CB  1 
ATOM   2327  C CG1 . ILE A 1 306 ? 158.399 180.401 180.942 1.00 31.31  ? 327 ILE A CG1 1 
ATOM   2328  C CG2 . ILE A 1 306 ? 156.004 179.900 181.497 1.00 31.31  ? 327 ILE A CG2 1 
ATOM   2329  C CD1 . ILE A 1 306 ? 158.682 179.156 180.135 1.00 31.31  ? 327 ILE A CD1 1 
ATOM   2330  N N   . THR A 1 307 ? 155.346 182.059 184.202 1.00 35.71  ? 328 THR A N   1 
ATOM   2331  C CA  . THR A 1 307 ? 154.301 181.929 185.203 1.00 35.71  ? 328 THR A CA  1 
ATOM   2332  C C   . THR A 1 307 ? 153.161 181.087 184.634 1.00 35.71  ? 328 THR A C   1 
ATOM   2333  O O   . THR A 1 307 ? 153.282 180.475 183.569 1.00 35.71  ? 328 THR A O   1 
ATOM   2334  C CB  . THR A 1 307 ? 153.821 183.306 185.654 1.00 35.71  ? 328 THR A CB  1 
ATOM   2335  O OG1 . THR A 1 307 ? 152.952 183.861 184.658 1.00 35.71  ? 328 THR A OG1 1 
ATOM   2336  C CG2 . THR A 1 307 ? 155.003 184.239 185.868 1.00 35.71  ? 328 THR A CG2 1 
ATOM   2337  N N   . ASP A 1 308 ? 152.035 181.042 185.347 1.00 39.37  ? 329 ASP A N   1 
ATOM   2338  C CA  . ASP A 1 308 ? 150.895 180.261 184.883 1.00 39.37  ? 329 ASP A CA  1 
ATOM   2339  C C   . ASP A 1 308 ? 150.149 180.946 183.745 1.00 39.37  ? 329 ASP A C   1 
ATOM   2340  O O   . ASP A 1 308 ? 149.596 180.263 182.876 1.00 39.37  ? 329 ASP A O   1 
ATOM   2341  C CB  . ASP A 1 308 ? 149.934 179.991 186.041 1.00 39.37  ? 329 ASP A CB  1 
ATOM   2342  C CG  . ASP A 1 308 ? 149.580 181.249 186.810 1.00 39.37  ? 329 ASP A CG  1 
ATOM   2343  O OD1 . ASP A 1 308 ? 150.219 182.296 186.575 1.00 39.37  ? 329 ASP A OD1 1 
ATOM   2344  O OD2 . ASP A 1 308 ? 148.659 181.191 187.651 1.00 39.37  ? 329 ASP A OD2 1 
ATOM   2345  N N   . ASN A 1 309 ? 150.117 182.280 183.730 1.00 35.77  ? 330 ASN A N   1 
ATOM   2346  C CA  . ASN A 1 309 ? 149.300 183.016 182.778 1.00 35.77  ? 330 ASN A CA  1 
ATOM   2347  C C   . ASN A 1 309 ? 150.074 183.911 181.821 1.00 35.77  ? 330 ASN A C   1 
ATOM   2348  O O   . ASN A 1 309 ? 149.523 184.277 180.779 1.00 35.77  ? 330 ASN A O   1 
ATOM   2349  C CB  . ASN A 1 309 ? 148.258 183.873 183.517 1.00 35.77  ? 330 ASN A CB  1 
ATOM   2350  C CG  . ASN A 1 309 ? 148.872 184.749 184.598 1.00 35.77  ? 330 ASN A CG  1 
ATOM   2351  O OD1 . ASN A 1 309 ? 150.088 184.770 184.790 1.00 35.77  ? 330 ASN A OD1 1 
ATOM   2352  N ND2 . ASN A 1 309 ? 148.024 185.478 185.312 1.00 35.77  ? 330 ASN A ND2 1 
ATOM   2353  N N   . SER A 1 310 ? 151.315 184.280 182.135 1.00 31.44  ? 331 SER A N   1 
ATOM   2354  C CA  . SER A 1 310 ? 152.030 185.231 181.297 1.00 31.44  ? 331 SER A CA  1 
ATOM   2355  C C   . SER A 1 310 ? 153.529 184.990 181.386 1.00 31.44  ? 331 SER A C   1 
ATOM   2356  O O   . SER A 1 310 ? 154.028 184.369 182.327 1.00 31.44  ? 331 SER A O   1 
ATOM   2357  C CB  . SER A 1 310 ? 151.706 186.675 181.693 1.00 31.44  ? 331 SER A CB  1 
ATOM   2358  O OG  . SER A 1 310 ? 152.494 187.591 180.955 1.00 31.44  ? 331 SER A OG  1 
ATOM   2359  N N   . TYR A 1 311 ? 154.239 185.499 180.382 1.00 30.26  ? 332 TYR A N   1 
ATOM   2360  C CA  . TYR A 1 311 ? 155.695 185.471 180.351 1.00 30.26  ? 332 TYR A CA  1 
ATOM   2361  C C   . TYR A 1 311 ? 156.243 186.765 180.933 1.00 30.26  ? 332 TYR A C   1 
ATOM   2362  O O   . TYR A 1 311 ? 155.815 187.856 180.546 1.00 30.26  ? 332 TYR A O   1 
ATOM   2363  C CB  . TYR A 1 311 ? 156.202 185.292 178.921 1.00 30.26  ? 332 TYR A CB  1 
ATOM   2364  C CG  . TYR A 1 311 ? 156.404 183.858 178.507 1.00 30.26  ? 332 TYR A CG  1 
ATOM   2365  C CD1 . TYR A 1 311 ? 155.343 182.965 178.498 1.00 30.26  ? 332 TYR A CD1 1 
ATOM   2366  C CD2 . TYR A 1 311 ? 157.655 183.400 178.112 1.00 30.26  ? 332 TYR A CD2 1 
ATOM   2367  C CE1 . TYR A 1 311 ? 155.523 181.652 178.119 1.00 30.26  ? 332 TYR A CE1 1 
ATOM   2368  C CE2 . TYR A 1 311 ? 157.845 182.086 177.726 1.00 30.26  ? 332 TYR A CE2 1 
ATOM   2369  C CZ  . TYR A 1 311 ? 156.774 181.218 177.732 1.00 30.26  ? 332 TYR A CZ  1 
ATOM   2370  O OH  . TYR A 1 311 ? 156.952 179.908 177.351 1.00 30.26  ? 332 TYR A OH  1 
ATOM   2371  N N   . VAL A 1 312 ? 157.189 186.642 181.858 1.00 32.94  ? 333 VAL A N   1 
ATOM   2372  C CA  . VAL A 1 312 ? 157.856 187.790 182.457 1.00 32.94  ? 333 VAL A CA  1 
ATOM   2373  C C   . VAL A 1 312 ? 159.317 187.742 182.043 1.00 32.94  ? 333 VAL A C   1 
ATOM   2374  O O   . VAL A 1 312 ? 160.022 186.772 182.349 1.00 32.94  ? 333 VAL A O   1 
ATOM   2375  C CB  . VAL A 1 312 ? 157.719 187.803 183.986 1.00 32.94  ? 333 VAL A CB  1 
ATOM   2376  C CG1 . VAL A 1 312 ? 158.450 188.999 184.570 1.00 32.94  ? 333 VAL A CG1 1 
ATOM   2377  C CG2 . VAL A 1 312 ? 156.258 187.823 184.378 1.00 32.94  ? 333 VAL A CG2 1 
ATOM   2378  N N   . CYS A 1 313 ? 159.770 188.783 181.355 1.00 38.14  ? 334 CYS A N   1 
ATOM   2379  C CA  . CYS A 1 313 ? 161.138 188.872 180.875 1.00 38.14  ? 334 CYS A CA  1 
ATOM   2380  C C   . CYS A 1 313 ? 161.825 190.077 181.499 1.00 38.14  ? 334 CYS A C   1 
ATOM   2381  O O   . CYS A 1 313 ? 161.179 191.070 181.846 1.00 38.14  ? 334 CYS A O   1 
ATOM   2382  C CB  . CYS A 1 313 ? 161.190 188.981 179.347 1.00 38.14  ? 334 CYS A CB  1 
ATOM   2383  S SG  . CYS A 1 313 ? 160.915 187.427 178.470 1.00 38.14  ? 334 CYS A SG  1 
ATOM   2384  N N   . ASP A 1 314 ? 163.146 189.966 181.652 1.00 47.22  ? 335 ASP A N   1 
ATOM   2385  C CA  . ASP A 1 314 ? 163.943 191.103 182.101 1.00 47.22  ? 335 ASP A CA  1 
ATOM   2386  C C   . ASP A 1 314 ? 163.961 192.205 181.051 1.00 47.22  ? 335 ASP A C   1 
ATOM   2387  O O   . ASP A 1 314 ? 163.966 193.395 181.389 1.00 47.22  ? 335 ASP A O   1 
ATOM   2388  C CB  . ASP A 1 314 ? 165.365 190.643 182.421 1.00 47.22  ? 335 ASP A CB  1 
ATOM   2389  C CG  . ASP A 1 314 ? 166.123 191.630 183.288 1.00 47.22  ? 335 ASP A CG  1 
ATOM   2390  O OD1 . ASP A 1 314 ? 165.512 192.610 183.762 1.00 47.22  ? 335 ASP A OD1 1 
ATOM   2391  O OD2 . ASP A 1 314 ? 167.337 191.426 183.492 1.00 47.22  ? 335 ASP A OD2 1 
ATOM   2392  N N   . ARG A 1 315 ? 163.951 191.826 179.777 1.00 55.78  ? 336 ARG A N   1 
ATOM   2393  C CA  . ARG A 1 315 ? 164.100 192.764 178.677 1.00 55.78  ? 336 ARG A CA  1 
ATOM   2394  C C   . ARG A 1 315 ? 163.545 192.090 177.429 1.00 55.78  ? 336 ARG A C   1 
ATOM   2395  O O   . ARG A 1 315 ? 163.408 190.864 177.383 1.00 55.78  ? 336 ARG A O   1 
ATOM   2396  C CB  . ARG A 1 315 ? 165.574 193.169 178.528 1.00 55.78  ? 336 ARG A CB  1 
ATOM   2397  C CG  . ARG A 1 315 ? 165.867 194.393 177.686 1.00 55.78  ? 336 ARG A CG  1 
ATOM   2398  C CD  . ARG A 1 315 ? 166.529 193.979 176.392 1.00 55.78  ? 336 ARG A CD  1 
ATOM   2399  N NE  . ARG A 1 315 ? 167.540 192.948 176.605 1.00 55.78  ? 336 ARG A NE  1 
ATOM   2400  C CZ  . ARG A 1 315 ? 168.778 193.176 177.028 1.00 55.78  ? 336 ARG A CZ  1 
ATOM   2401  N NH1 . ARG A 1 315 ? 169.211 194.400 177.279 1.00 55.78  ? 336 ARG A NH1 1 
ATOM   2402  N NH2 . ARG A 1 315 ? 169.603 192.147 177.201 1.00 55.78  ? 336 ARG A NH2 1 
ATOM   2403  N N   . ASP A 1 316 ? 163.196 192.905 176.432 1.00 43.63  ? 337 ASP A N   1 
ATOM   2404  C CA  . ASP A 1 316 ? 162.589 192.398 175.206 1.00 43.63  ? 337 ASP A CA  1 
ATOM   2405  C C   . ASP A 1 316 ? 163.577 191.551 174.411 1.00 43.63  ? 337 ASP A C   1 
ATOM   2406  O O   . ASP A 1 316 ? 164.740 191.923 174.235 1.00 43.63  ? 337 ASP A O   1 
ATOM   2407  C CB  . ASP A 1 316 ? 162.086 193.557 174.347 1.00 43.63  ? 337 ASP A CB  1 
ATOM   2408  C CG  . ASP A 1 316 ? 160.947 193.153 173.434 1.00 43.63  ? 337 ASP A CG  1 
ATOM   2409  O OD1 . ASP A 1 316 ? 160.568 191.963 173.442 1.00 43.63  ? 337 ASP A OD1 1 
ATOM   2410  O OD2 . ASP A 1 316 ? 160.428 194.026 172.708 1.00 43.63  ? 337 ASP A OD2 1 
ATOM   2411  N N   . TYR A 1 317 ? 163.101 190.406 173.928 1.00 48.87  ? 338 TYR A N   1 
ATOM   2412  C CA  . TYR A 1 317 ? 163.931 189.393 173.284 1.00 48.87  ? 338 TYR A CA  1 
ATOM   2413  C C   . TYR A 1 317 ? 163.299 188.935 171.977 1.00 48.87  ? 338 TYR A C   1 
ATOM   2414  O O   . TYR A 1 317 ? 163.186 187.740 171.700 1.00 48.87  ? 338 TYR A O   1 
ATOM   2415  C CB  . TYR A 1 317 ? 164.143 188.197 174.208 1.00 48.87  ? 338 TYR A CB  1 
ATOM   2416  C CG  . TYR A 1 317 ? 165.124 188.434 175.331 1.00 48.87  ? 338 TYR A CG  1 
ATOM   2417  C CD1 . TYR A 1 317 ? 166.276 189.184 175.129 1.00 48.87  ? 338 TYR A CD1 1 
ATOM   2418  C CD2 . TYR A 1 317 ? 164.900 187.900 176.595 1.00 48.87  ? 338 TYR A CD2 1 
ATOM   2419  C CE1 . TYR A 1 317 ? 167.178 189.400 176.157 1.00 48.87  ? 338 TYR A CE1 1 
ATOM   2420  C CE2 . TYR A 1 317 ? 165.795 188.109 177.629 1.00 48.87  ? 338 TYR A CE2 1 
ATOM   2421  C CZ  . TYR A 1 317 ? 166.931 188.860 177.403 1.00 48.87  ? 338 TYR A CZ  1 
ATOM   2422  O OH  . TYR A 1 317 ? 167.823 189.071 178.428 1.00 48.87  ? 338 TYR A OH  1 
ATOM   2423  N N   . SER A 1 318 ? 162.873 189.884 171.150 1.00 54.84  ? 339 SER A N   1 
ATOM   2424  C CA  . SER A 1 318 ? 162.203 189.566 169.895 1.00 54.84  ? 339 SER A CA  1 
ATOM   2425  C C   . SER A 1 318 ? 163.243 189.353 168.800 1.00 54.84  ? 339 SER A C   1 
ATOM   2426  O O   . SER A 1 318 ? 163.981 190.279 168.447 1.00 54.84  ? 339 SER A O   1 
ATOM   2427  C CB  . SER A 1 318 ? 161.229 190.677 169.508 1.00 54.84  ? 339 SER A CB  1 
ATOM   2428  O OG  . SER A 1 318 ? 160.560 190.365 168.300 1.00 54.84  ? 339 SER A OG  1 
ATOM   2429  N N   . LEU A 1 319 ? 163.297 188.133 168.263 1.00 55.51  ? 340 LEU A N   1 
ATOM   2430  C CA  . LEU A 1 319 ? 164.202 187.733 167.194 1.00 55.51  ? 340 LEU A CA  1 
ATOM   2431  C C   . LEU A 1 319 ? 163.433 187.560 165.885 1.00 55.51  ? 340 LEU A C   1 
ATOM   2432  O O   . LEU A 1 319 ? 162.271 187.144 165.899 1.00 55.51  ? 340 LEU A O   1 
ATOM   2433  C CB  . LEU A 1 319 ? 164.928 186.422 167.533 1.00 55.51  ? 340 LEU A CB  1 
ATOM   2434  C CG  . LEU A 1 319 ? 166.150 186.428 168.463 1.00 55.51  ? 340 LEU A CG  1 
ATOM   2435  C CD1 . LEU A 1 319 ? 165.808 186.669 169.927 1.00 55.51  ? 340 LEU A CD1 1 
ATOM   2436  C CD2 . LEU A 1 319 ? 166.934 185.132 168.302 1.00 55.51  ? 340 LEU A CD2 1 
ATOM   2437  N N   . PRO A 1 320 ? 164.040 187.867 164.738 1.00 63.07  ? 341 PRO A N   1 
ATOM   2438  C CA  . PRO A 1 320 ? 163.329 187.718 163.466 1.00 63.07  ? 341 PRO A CA  1 
ATOM   2439  C C   . PRO A 1 320 ? 163.265 186.258 163.038 1.00 63.07  ? 341 PRO A C   1 
ATOM   2440  O O   . PRO A 1 320 ? 163.960 185.389 163.564 1.00 63.07  ? 341 PRO A O   1 
ATOM   2441  C CB  . PRO A 1 320 ? 164.174 188.543 162.495 1.00 63.07  ? 341 PRO A CB  1 
ATOM   2442  C CG  . PRO A 1 320 ? 165.543 188.396 163.023 1.00 63.07  ? 341 PRO A CG  1 
ATOM   2443  C CD  . PRO A 1 320 ? 165.405 188.385 164.526 1.00 63.07  ? 341 PRO A CD  1 
ATOM   2444  N N   . MET A 1 321 ? 162.405 186.004 162.056 1.00 72.43  ? 342 MET A N   1 
ATOM   2445  C CA  . MET A 1 321 ? 162.151 184.661 161.565 1.00 72.43  ? 342 MET A CA  1 
ATOM   2446  C C   . MET A 1 321 ? 162.153 184.651 160.044 1.00 72.43  ? 342 MET A C   1 
ATOM   2447  O O   . MET A 1 321 ? 161.924 185.673 159.391 1.00 72.43  ? 342 MET A O   1 
ATOM   2448  C CB  . MET A 1 321 ? 160.821 184.124 162.107 1.00 72.43  ? 342 MET A CB  1 
ATOM   2449  C CG  . MET A 1 321 ? 159.607 184.902 161.637 1.00 72.43  ? 342 MET A CG  1 
ATOM   2450  S SD  . MET A 1 321 ? 158.071 184.243 162.307 1.00 72.43  ? 342 MET A SD  1 
ATOM   2451  C CE  . MET A 1 321 ? 157.910 182.728 161.373 1.00 72.43  ? 342 MET A CE  1 
ATOM   2452  N N   . ASN A 1 322 ? 162.418 183.473 159.491 1.00 91.03  ? 343 ASN A N   1 
ATOM   2453  C CA  . ASN A 1 322 ? 162.506 183.320 158.047 1.00 91.03  ? 343 ASN A CA  1 
ATOM   2454  C C   . ASN A 1 322 ? 161.116 183.404 157.415 1.00 91.03  ? 343 ASN A C   1 
ATOM   2455  O O   . ASN A 1 322 ? 160.140 182.922 158.000 1.00 91.03  ? 343 ASN A O   1 
ATOM   2456  C CB  . ASN A 1 322 ? 163.166 181.985 157.707 1.00 91.03  ? 343 ASN A CB  1 
ATOM   2457  C CG  . ASN A 1 322 ? 163.764 181.964 156.319 1.00 91.03  ? 343 ASN A CG  1 
ATOM   2458  O OD1 . ASN A 1 322 ? 163.047 181.884 155.323 1.00 91.03  ? 343 ASN A OD1 1 
ATOM   2459  N ND2 . ASN A 1 322 ? 165.087 182.041 156.245 1.00 91.03  ? 343 ASN A ND2 1 
ATOM   2460  N N   . PRO A 1 323 ? 160.991 184.040 156.242 1.00 97.27  ? 344 PRO A N   1 
ATOM   2461  C CA  . PRO A 1 323 ? 159.688 184.081 155.551 1.00 97.27  ? 344 PRO A CA  1 
ATOM   2462  C C   . PRO A 1 323 ? 159.161 182.722 155.120 1.00 97.27  ? 344 PRO A C   1 
ATOM   2463  O O   . PRO A 1 323 ? 157.941 182.574 154.965 1.00 97.27  ? 344 PRO A O   1 
ATOM   2464  C CB  . PRO A 1 323 ? 159.966 184.977 154.337 1.00 97.27  ? 344 PRO A CB  1 
ATOM   2465  C CG  . PRO A 1 323 ? 161.087 185.844 154.769 1.00 97.27  ? 344 PRO A CG  1 
ATOM   2466  C CD  . PRO A 1 323 ? 161.953 184.984 155.647 1.00 97.27  ? 344 PRO A CD  1 
ATOM   2467  N N   . ILE A 1 324 ? 160.035 181.732 154.917 1.00 98.98  ? 345 ILE A N   1 
ATOM   2468  C CA  . ILE A 1 324 ? 159.565 180.378 154.639 1.00 98.98  ? 345 ILE A CA  1 
ATOM   2469  C C   . ILE A 1 324 ? 158.897 179.788 155.876 1.00 98.98  ? 345 ILE A C   1 
ATOM   2470  O O   . ILE A 1 324 ? 157.920 179.043 155.770 1.00 98.98  ? 345 ILE A O   1 
ATOM   2471  C CB  . ILE A 1 324 ? 160.725 179.505 154.122 1.00 98.98  ? 345 ILE A CB  1 
ATOM   2472  C CG1 . ILE A 1 324 ? 161.416 180.187 152.940 1.00 98.98  ? 345 ILE A CG1 1 
ATOM   2473  C CG2 . ILE A 1 324 ? 160.213 178.149 153.668 1.00 98.98  ? 345 ILE A CG2 1 
ATOM   2474  C CD1 . ILE A 1 324 ? 160.502 180.468 151.764 1.00 98.98  ? 345 ILE A CD1 1 
ATOM   2475  N N   . LEU A 1 325 ? 159.379 180.133 157.070 1.00 94.89  ? 346 LEU A N   1 
ATOM   2476  C CA  . LEU A 1 325 ? 158.675 179.745 158.296 1.00 94.89  ? 346 LEU A CA  1 
ATOM   2477  C C   . LEU A 1 325 ? 157.347 180.480 158.442 1.00 94.89  ? 346 LEU A C   1 
ATOM   2478  O O   . LEU A 1 325 ? 156.397 179.932 159.015 1.00 94.89  ? 346 LEU A O   1 
ATOM   2479  C CB  . LEU A 1 325 ? 159.561 179.992 159.516 1.00 94.89  ? 346 LEU A CB  1 
ATOM   2480  C CG  . LEU A 1 325 ? 160.484 178.861 160.007 1.00 94.89  ? 346 LEU A CG  1 
ATOM   2481  C CD1 . LEU A 1 325 ? 159.657 177.649 160.373 1.00 94.89  ? 346 LEU A CD1 1 
ATOM   2482  C CD2 . LEU A 1 325 ? 161.581 178.483 159.012 1.00 94.89  ? 346 LEU A CD2 1 
ATOM   2483  N N   . ARG A 1 326 ? 157.261 181.716 157.932 1.00 92.99  ? 347 ARG A N   1 
ATOM   2484  C CA  . ARG A 1 326 ? 155.980 182.421 157.902 1.00 92.99  ? 347 ARG A CA  1 
ATOM   2485  C C   . ARG A 1 326 ? 154.995 181.729 156.964 1.00 92.99  ? 347 ARG A C   1 
ATOM   2486  O O   . ARG A 1 326 ? 153.802 181.616 157.274 1.00 92.99  ? 347 ARG A O   1 
ATOM   2487  C CB  . ARG A 1 326 ? 156.199 183.879 157.484 1.00 92.99  ? 347 ARG A CB  1 
ATOM   2488  C CG  . ARG A 1 326 ? 154.935 184.720 157.408 1.00 92.99  ? 347 ARG A CG  1 
ATOM   2489  C CD  . ARG A 1 326 ? 155.202 186.060 156.746 1.00 92.99  ? 347 ARG A CD  1 
ATOM   2490  N NE  . ARG A 1 326 ? 156.377 186.715 157.309 1.00 92.99  ? 347 ARG A NE  1 
ATOM   2491  C CZ  . ARG A 1 326 ? 156.373 187.454 158.411 1.00 92.99  ? 347 ARG A CZ  1 
ATOM   2492  N NH1 . ARG A 1 326 ? 155.265 187.652 159.107 1.00 92.99  ? 347 ARG A NH1 1 
ATOM   2493  N NH2 . ARG A 1 326 ? 157.508 188.013 158.821 1.00 92.99  ? 347 ARG A NH2 1 
ATOM   2494  N N   . GLU A 1 327 ? 155.484 181.245 155.818 1.00 100.19 ? 348 GLU A N   1 
ATOM   2495  C CA  . GLU A 1 327 ? 154.638 180.466 154.920 1.00 100.19 ? 348 GLU A CA  1 
ATOM   2496  C C   . GLU A 1 327 ? 154.278 179.109 155.516 1.00 100.19 ? 348 GLU A C   1 
ATOM   2497  O O   . GLU A 1 327 ? 153.196 178.580 155.236 1.00 100.19 ? 348 GLU A O   1 
ATOM   2498  C CB  . GLU A 1 327 ? 155.329 180.281 153.568 1.00 100.19 ? 348 GLU A CB  1 
ATOM   2499  C CG  . GLU A 1 327 ? 155.636 181.579 152.831 1.00 100.19 ? 348 GLU A CG  1 
ATOM   2500  C CD  . GLU A 1 327 ? 154.550 182.627 152.994 1.00 100.19 ? 348 GLU A CD  1 
ATOM   2501  O OE1 . GLU A 1 327 ? 153.446 182.434 152.442 1.00 100.19 ? 348 GLU A OE1 1 
ATOM   2502  O OE2 . GLU A 1 327 ? 154.806 183.654 153.658 1.00 100.19 ? 348 GLU A OE2 1 
ATOM   2503  N N   . CYS A 1 328 ? 155.180 178.535 156.318 1.00 93.31  ? 349 CYS A N   1 
ATOM   2504  C CA  . CYS A 1 328 ? 154.881 177.330 157.088 1.00 93.31  ? 349 CYS A CA  1 
ATOM   2505  C C   . CYS A 1 328 ? 153.736 177.550 158.063 1.00 93.31  ? 349 CYS A C   1 
ATOM   2506  O O   . CYS A 1 328 ? 152.840 176.706 158.183 1.00 93.31  ? 349 CYS A O   1 
ATOM   2507  C CB  . CYS A 1 328 ? 156.131 176.885 157.845 1.00 93.31  ? 349 CYS A CB  1 
ATOM   2508  S SG  . CYS A 1 328 ? 155.955 175.426 158.899 1.00 93.31  ? 349 CYS A SG  1 
ATOM   2509  N N   . PHE A 1 329 ? 153.751 178.676 158.770 1.00 81.67  ? 350 PHE A N   1 
ATOM   2510  C CA  . PHE A 1 329 ? 152.702 178.922 159.749 1.00 81.67  ? 350 PHE A CA  1 
ATOM   2511  C C   . PHE A 1 329 ? 151.391 179.355 159.100 1.00 81.67  ? 350 PHE A C   1 
ATOM   2512  O O   . PHE A 1 329 ? 150.319 179.060 159.637 1.00 81.67  ? 350 PHE A O   1 
ATOM   2513  C CB  . PHE A 1 329 ? 153.170 179.961 160.767 1.00 81.67  ? 350 PHE A CB  1 
ATOM   2514  C CG  . PHE A 1 329 ? 153.809 179.359 161.984 1.00 81.67  ? 350 PHE A CG  1 
ATOM   2515  C CD1 . PHE A 1 329 ? 155.170 179.091 162.003 1.00 81.67  ? 350 PHE A CD1 1 
ATOM   2516  C CD2 . PHE A 1 329 ? 153.049 179.036 163.096 1.00 81.67  ? 350 PHE A CD2 1 
ATOM   2517  C CE1 . PHE A 1 329 ? 155.765 178.527 163.115 1.00 81.67  ? 350 PHE A CE1 1 
ATOM   2518  C CE2 . PHE A 1 329 ? 153.638 178.470 164.212 1.00 81.67  ? 350 PHE A CE2 1 
ATOM   2519  C CZ  . PHE A 1 329 ? 154.996 178.214 164.220 1.00 81.67  ? 350 PHE A CZ  1 
ATOM   2520  N N   . GLU A 1 330 ? 151.441 180.032 157.951 1.00 93.98  ? 351 GLU A N   1 
ATOM   2521  C CA  . GLU A 1 330 ? 150.208 180.589 157.393 1.00 93.98  ? 351 GLU A CA  1 
ATOM   2522  C C   . GLU A 1 330 ? 149.409 179.557 156.600 1.00 93.98  ? 351 GLU A C   1 
ATOM   2523  O O   . GLU A 1 330 ? 148.316 179.154 157.010 1.00 93.98  ? 351 GLU A O   1 
ATOM   2524  C CB  . GLU A 1 330 ? 150.545 181.797 156.513 1.00 93.98  ? 351 GLU A CB  1 
ATOM   2525  C CG  . GLU A 1 330 ? 150.704 183.095 157.275 1.00 93.98  ? 351 GLU A CG  1 
ATOM   2526  C CD  . GLU A 1 330 ? 151.548 184.103 156.524 1.00 93.98  ? 351 GLU A CD  1 
ATOM   2527  O OE1 . GLU A 1 330 ? 152.192 183.714 155.526 1.00 93.98  ? 351 GLU A OE1 1 
ATOM   2528  O OE2 . GLU A 1 330 ? 151.577 185.281 156.934 1.00 93.98  ? 351 GLU A OE2 1 
ATOM   2529  N N   . GLY A 1 331 ? 149.936 179.120 155.457 1.00 90.82  ? 352 GLY A N   1 
ATOM   2530  C CA  . GLY A 1 331 ? 149.190 178.210 154.607 1.00 90.82  ? 352 GLY A CA  1 
ATOM   2531  C C   . GLY A 1 331 ? 149.894 176.955 154.130 1.00 90.82  ? 352 GLY A C   1 
ATOM   2532  O O   . GLY A 1 331 ? 149.241 175.948 153.842 1.00 90.82  ? 352 GLY A O   1 
ATOM   2533  N N   . ASN A 1 332 ? 151.220 176.996 154.041 1.00 98.60  ? 353 ASN A N   1 
ATOM   2534  C CA  . ASN A 1 332 ? 151.989 175.992 153.306 1.00 98.60  ? 353 ASN A CA  1 
ATOM   2535  C C   . ASN A 1 332 ? 152.481 174.923 154.273 1.00 98.60  ? 353 ASN A C   1 
ATOM   2536  O O   . ASN A 1 332 ? 153.404 175.156 155.056 1.00 98.60  ? 353 ASN A O   1 
ATOM   2537  C CB  . ASN A 1 332 ? 153.156 176.643 152.570 1.00 98.60  ? 353 ASN A CB  1 
ATOM   2538  C CG  . ASN A 1 332 ? 152.710 177.506 151.406 1.00 98.60  ? 353 ASN A CG  1 
ATOM   2539  O OD1 . ASN A 1 332 ? 153.492 178.295 150.875 1.00 98.60  ? 353 ASN A OD1 1 
ATOM   2540  N ND2 . ASN A 1 332 ? 151.456 177.353 150.991 1.00 98.60  ? 353 ASN A ND2 1 
ATOM   2541  N N   . THR A 1 333 ? 151.871 173.740 154.209 1.00 84.89  ? 354 THR A N   1 
ATOM   2542  C CA  . THR A 1 333 ? 152.384 172.614 154.979 1.00 84.89  ? 354 THR A CA  1 
ATOM   2543  C C   . THR A 1 333 ? 153.640 172.018 154.358 1.00 84.89  ? 354 THR A C   1 
ATOM   2544  O O   . THR A 1 333 ? 154.398 171.337 155.056 1.00 84.89  ? 354 THR A O   1 
ATOM   2545  C CB  . THR A 1 333 ? 151.311 171.536 155.123 1.00 84.89  ? 354 THR A CB  1 
ATOM   2546  O OG1 . THR A 1 333 ? 150.905 171.088 153.825 1.00 84.89  ? 354 THR A OG1 1 
ATOM   2547  C CG2 . THR A 1 333 ? 150.104 172.086 155.860 1.00 84.89  ? 354 THR A CG2 1 
ATOM   2548  N N   . SER A 1 334 ? 153.878 172.258 153.066 1.00 83.95  ? 355 SER A N   1 
ATOM   2549  C CA  . SER A 1 334 ? 155.080 171.759 152.410 1.00 83.95  ? 355 SER A CA  1 
ATOM   2550  C C   . SER A 1 334 ? 156.320 172.564 152.770 1.00 83.95  ? 355 SER A C   1 
ATOM   2551  O O   . SER A 1 334 ? 157.439 172.069 152.596 1.00 83.95  ? 355 SER A O   1 
ATOM   2552  C CB  . SER A 1 334 ? 154.889 171.752 150.892 1.00 83.95  ? 355 SER A CB  1 
ATOM   2553  O OG  . SER A 1 334 ? 154.986 173.059 150.354 1.00 83.95  ? 355 SER A OG  1 
ATOM   2554  N N   . SER A 1 335 ? 156.151 173.783 153.277 1.00 88.05  ? 356 SER A N   1 
ATOM   2555  C CA  . SER A 1 335 ? 157.278 174.579 153.740 1.00 88.05  ? 356 SER A CA  1 
ATOM   2556  C C   . SER A 1 335 ? 157.740 174.183 155.135 1.00 88.05  ? 356 SER A C   1 
ATOM   2557  O O   . SER A 1 335 ? 158.754 174.708 155.607 1.00 88.05  ? 356 SER A O   1 
ATOM   2558  C CB  . SER A 1 335 ? 156.909 176.062 153.721 1.00 88.05  ? 356 SER A CB  1 
ATOM   2559  O OG  . SER A 1 335 ? 156.634 176.490 152.400 1.00 88.05  ? 356 SER A OG  1 
ATOM   2560  N N   . CYS A 1 336 ? 157.021 173.282 155.798 1.00 82.38  ? 357 CYS A N   1 
ATOM   2561  C CA  . CYS A 1 336 ? 157.342 172.856 157.151 1.00 82.38  ? 357 CYS A CA  1 
ATOM   2562  C C   . CYS A 1 336 ? 158.181 171.587 157.119 1.00 82.38  ? 357 CYS A C   1 
ATOM   2563  O O   . CYS A 1 336 ? 157.774 170.579 156.532 1.00 82.38  ? 357 CYS A O   1 
ATOM   2564  C CB  . CYS A 1 336 ? 156.057 172.631 157.944 1.00 82.38  ? 357 CYS A CB  1 
ATOM   2565  S SG  . CYS A 1 336 ? 154.946 174.039 157.829 1.00 82.38  ? 357 CYS A SG  1 
ATOM   2566  N N   . GLY A 1 337 ? 159.342 171.636 157.765 1.00 70.59  ? 358 GLY A N   1 
ATOM   2567  C CA  . GLY A 1 337 ? 160.258 170.519 157.763 1.00 70.59  ? 358 GLY A CA  1 
ATOM   2568  C C   . GLY A 1 337 ? 159.853 169.421 158.727 1.00 70.59  ? 358 GLY A C   1 
ATOM   2569  O O   . GLY A 1 337 ? 158.847 169.494 159.431 1.00 70.59  ? 358 GLY A O   1 
ATOM   2570  N N   . ARG A 1 338 ? 160.672 168.372 158.749 1.00 65.49  ? 359 ARG A N   1 
ATOM   2571  C CA  . ARG A 1 338 ? 160.407 167.208 159.579 1.00 65.49  ? 359 ARG A CA  1 
ATOM   2572  C C   . ARG A 1 338 ? 161.728 166.564 159.970 1.00 65.49  ? 359 ARG A C   1 
ATOM   2573  O O   . ARG A 1 338 ? 162.750 166.736 159.301 1.00 65.49  ? 359 ARG A O   1 
ATOM   2574  C CB  . ARG A 1 338 ? 159.512 166.197 158.853 1.00 65.49  ? 359 ARG A CB  1 
ATOM   2575  C CG  . ARG A 1 338 ? 160.080 165.758 157.519 1.00 65.49  ? 359 ARG A CG  1 
ATOM   2576  C CD  . ARG A 1 338 ? 159.279 164.641 156.877 1.00 65.49  ? 359 ARG A CD  1 
ATOM   2577  N NE  . ARG A 1 338 ? 159.843 164.268 155.585 1.00 65.49  ? 359 ARG A NE  1 
ATOM   2578  C CZ  . ARG A 1 338 ? 159.485 163.198 154.889 1.00 65.49  ? 359 ARG A CZ  1 
ATOM   2579  N NH1 . ARG A 1 338 ? 158.571 162.355 155.338 1.00 65.49  ? 359 ARG A NH1 1 
ATOM   2580  N NH2 . ARG A 1 338 ? 160.061 162.967 153.713 1.00 65.49  ? 359 ARG A NH2 1 
ATOM   2581  N N   . GLU A 1 339 ? 161.694 165.819 161.072 1.00 62.60  ? 360 GLU A N   1 
ATOM   2582  C CA  . GLU A 1 339 ? 162.862 165.101 161.560 1.00 62.60  ? 360 GLU A CA  1 
ATOM   2583  C C   . GLU A 1 339 ? 162.445 163.697 161.972 1.00 62.60  ? 360 GLU A C   1 
ATOM   2584  O O   . GLU A 1 339 ? 161.284 163.451 162.310 1.00 62.60  ? 360 GLU A O   1 
ATOM   2585  C CB  . GLU A 1 339 ? 163.541 165.846 162.724 1.00 62.60  ? 360 GLU A CB  1 
ATOM   2586  C CG  . GLU A 1 339 ? 162.868 165.699 164.080 1.00 62.60  ? 360 GLU A CG  1 
ATOM   2587  C CD  . GLU A 1 339 ? 163.357 166.725 165.083 1.00 62.60  ? 360 GLU A CD  1 
ATOM   2588  O OE1 . GLU A 1 339 ? 164.086 167.654 164.677 1.00 62.60  ? 360 GLU A OE1 1 
ATOM   2589  O OE2 . GLU A 1 339 ? 163.015 166.605 166.278 1.00 62.60  ? 360 GLU A OE2 1 
ATOM   2590  N N   . MET A 1 340 ? 163.405 162.778 161.928 1.00 64.27  ? 361 MET A N   1 
ATOM   2591  C CA  . MET A 1 340 ? 163.161 161.355 162.122 1.00 64.27  ? 361 MET A CA  1 
ATOM   2592  C C   . MET A 1 340 ? 163.657 160.925 163.494 1.00 64.27  ? 361 MET A C   1 
ATOM   2593  O O   . MET A 1 340 ? 164.805 161.202 163.858 1.00 64.27  ? 361 MET A O   1 
ATOM   2594  C CB  . MET A 1 340 ? 163.860 160.534 161.035 1.00 64.27  ? 361 MET A CB  1 
ATOM   2595  C CG  . MET A 1 340 ? 163.868 159.035 161.288 1.00 64.27  ? 361 MET A CG  1 
ATOM   2596  S SD  . MET A 1 340 ? 165.248 158.197 160.490 1.00 64.27  ? 361 MET A SD  1 
ATOM   2597  C CE  . MET A 1 340 ? 165.174 156.595 161.287 1.00 64.27  ? 361 MET A CE  1 
ATOM   2598  N N   . VAL A 1 341 ? 162.790 160.255 164.257 1.00 65.35  ? 362 VAL A N   1 
ATOM   2599  C CA  . VAL A 1 341 ? 163.162 159.678 165.542 1.00 65.35  ? 362 VAL A CA  1 
ATOM   2600  C C   . VAL A 1 341 ? 162.676 158.237 165.599 1.00 65.35  ? 362 VAL A C   1 
ATOM   2601  O O   . VAL A 1 341 ? 161.778 157.825 164.862 1.00 65.35  ? 362 VAL A O   1 
ATOM   2602  C CB  . VAL A 1 341 ? 162.602 160.472 166.745 1.00 65.35  ? 362 VAL A CB  1 
ATOM   2603  C CG1 . VAL A 1 341 ? 163.256 161.844 166.852 1.00 65.35  ? 362 VAL A CG1 1 
ATOM   2604  C CG2 . VAL A 1 341 ? 161.089 160.600 166.640 1.00 65.35  ? 362 VAL A CG2 1 
ATOM   2605  N N   . LEU A 1 342 ? 163.297 157.464 166.490 1.00 68.32  ? 363 LEU A N   1 
ATOM   2606  C CA  . LEU A 1 342 ? 162.847 156.109 166.776 1.00 68.32  ? 363 LEU A CA  1 
ATOM   2607  C C   . LEU A 1 342 ? 162.791 155.820 168.268 1.00 68.32  ? 363 LEU A C   1 
ATOM   2608  O O   . LEU A 1 342 ? 162.488 154.684 168.648 1.00 68.32  ? 363 LEU A O   1 
ATOM   2609  C CB  . LEU A 1 342 ? 163.745 155.057 166.090 1.00 68.32  ? 363 LEU A CB  1 
ATOM   2610  C CG  . LEU A 1 342 ? 165.163 154.721 166.578 1.00 68.32  ? 363 LEU A CG  1 
ATOM   2611  C CD1 . LEU A 1 342 ? 165.608 153.404 165.963 1.00 68.32  ? 363 LEU A CD1 1 
ATOM   2612  C CD2 . LEU A 1 342 ? 166.186 155.796 166.251 1.00 68.32  ? 363 LEU A CD2 1 
ATOM   2613  N N   . ASN A 1 343 ? 163.070 156.805 169.117 1.00 78.98  ? 364 ASN A N   1 
ATOM   2614  C CA  . ASN A 1 343 ? 163.048 156.633 170.560 1.00 78.98  ? 364 ASN A CA  1 
ATOM   2615  C C   . ASN A 1 343 ? 161.615 156.493 171.073 1.00 78.98  ? 364 ASN A C   1 
ATOM   2616  O O   . ASN A 1 343 ? 160.643 156.837 170.395 1.00 78.98  ? 364 ASN A O   1 
ATOM   2617  C CB  . ASN A 1 343 ? 163.763 157.808 171.228 1.00 78.98  ? 364 ASN A CB  1 
ATOM   2618  C CG  . ASN A 1 343 ? 163.369 159.147 170.627 1.00 78.98  ? 364 ASN A CG  1 
ATOM   2619  O OD1 . ASN A 1 343 ? 162.424 159.236 169.846 1.00 78.98  ? 364 ASN A OD1 1 
ATOM   2620  N ND2 . ASN A 1 343 ? 164.126 160.187 170.952 1.00 78.98  ? 364 ASN A ND2 1 
ATOM   2621  N N   . SER A 1 344 ? 161.495 155.974 172.294 1.00 77.40  ? 365 SER A N   1 
ATOM   2622  C CA  . SER A 1 344 ? 160.195 155.611 172.842 1.00 77.40  ? 365 SER A CA  1 
ATOM   2623  C C   . SER A 1 344 ? 159.473 156.761 173.531 1.00 77.40  ? 365 SER A C   1 
ATOM   2624  O O   . SER A 1 344 ? 158.262 156.658 173.758 1.00 77.40  ? 365 SER A O   1 
ATOM   2625  C CB  . SER A 1 344 ? 160.348 154.454 173.834 1.00 77.40  ? 365 SER A CB  1 
ATOM   2626  O OG  . SER A 1 344 ? 161.076 154.859 174.981 1.00 77.40  ? 365 SER A OG  1 
ATOM   2627  N N   . TYR A 1 345 ? 160.165 157.847 173.867 1.00 69.36  ? 366 TYR A N   1 
ATOM   2628  C CA  . TYR A 1 345 ? 159.534 158.945 174.605 1.00 69.36  ? 366 TYR A CA  1 
ATOM   2629  C C   . TYR A 1 345 ? 158.968 160.016 173.671 1.00 69.36  ? 366 TYR A C   1 
ATOM   2630  O O   . TYR A 1 345 ? 159.168 161.216 173.845 1.00 69.36  ? 366 TYR A O   1 
ATOM   2631  C CB  . TYR A 1 345 ? 160.508 159.539 175.626 1.00 69.36  ? 366 TYR A CB  1 
ATOM   2632  C CG  . TYR A 1 345 ? 161.799 160.180 175.116 1.00 69.36  ? 366 TYR A CG  1 
ATOM   2633  C CD1 . TYR A 1 345 ? 162.851 159.407 174.627 1.00 69.36  ? 366 TYR A CD1 1 
ATOM   2634  C CD2 . TYR A 1 345 ? 161.981 161.561 175.177 1.00 69.36  ? 366 TYR A CD2 1 
ATOM   2635  C CE1 . TYR A 1 345 ? 164.024 159.991 174.186 1.00 69.36  ? 366 TYR A CE1 1 
ATOM   2636  C CE2 . TYR A 1 345 ? 163.149 162.153 174.732 1.00 69.36  ? 366 TYR A CE2 1 
ATOM   2637  C CZ  . TYR A 1 345 ? 164.166 161.363 174.238 1.00 69.36  ? 366 TYR A CZ  1 
ATOM   2638  O OH  . TYR A 1 345 ? 165.331 161.947 173.799 1.00 69.36  ? 366 TYR A OH  1 
ATOM   2639  N N   . ILE A 1 346 ? 158.195 159.579 172.688 1.00 54.84  ? 367 ILE A N   1 
ATOM   2640  C CA  . ILE A 1 346 ? 157.488 160.471 171.776 1.00 54.84  ? 367 ILE A CA  1 
ATOM   2641  C C   . ILE A 1 346 ? 156.000 160.371 172.094 1.00 54.84  ? 367 ILE A C   1 
ATOM   2642  O O   . ILE A 1 346 ? 155.434 159.272 172.014 1.00 54.84  ? 367 ILE A O   1 
ATOM   2643  C CB  . ILE A 1 346 ? 157.764 160.118 170.307 1.00 54.84  ? 367 ILE A CB  1 
ATOM   2644  C CG1 . ILE A 1 346 ? 159.234 160.370 169.971 1.00 54.84  ? 367 ILE A CG1 1 
ATOM   2645  C CG2 . ILE A 1 346 ? 156.864 160.927 169.392 1.00 54.84  ? 367 ILE A CG2 1 
ATOM   2646  C CD1 . ILE A 1 346 ? 159.674 161.798 170.185 1.00 54.84  ? 367 ILE A CD1 1 
ATOM   2647  N N   . PRO A 1 347 ? 155.344 161.461 172.495 1.00 46.24  ? 368 PRO A N   1 
ATOM   2648  C CA  . PRO A 1 347 ? 153.896 161.402 172.735 1.00 46.24  ? 368 PRO A CA  1 
ATOM   2649  C C   . PRO A 1 347 ? 153.129 161.197 171.438 1.00 46.24  ? 368 PRO A C   1 
ATOM   2650  O O   . PRO A 1 347 ? 153.494 161.727 170.387 1.00 46.24  ? 368 PRO A O   1 
ATOM   2651  C CB  . PRO A 1 347 ? 153.583 162.765 173.363 1.00 46.24  ? 368 PRO A CB  1 
ATOM   2652  C CG  . PRO A 1 347 ? 154.678 163.658 172.892 1.00 46.24  ? 368 PRO A CG  1 
ATOM   2653  C CD  . PRO A 1 347 ? 155.900 162.797 172.768 1.00 46.24  ? 368 PRO A CD  1 
ATOM   2654  N N   . LEU A 1 348 ? 152.055 160.414 171.524 1.00 39.56  ? 369 LEU A N   1 
ATOM   2655  C CA  . LEU A 1 348 ? 151.298 160.015 170.349 1.00 39.56  ? 369 LEU A CA  1 
ATOM   2656  C C   . LEU A 1 348 ? 149.859 160.507 170.362 1.00 39.56  ? 369 LEU A C   1 
ATOM   2657  O O   . LEU A 1 348 ? 149.137 160.285 169.382 1.00 39.56  ? 369 LEU A O   1 
ATOM   2658  C CB  . LEU A 1 348 ? 151.324 158.488 170.203 1.00 39.56  ? 369 LEU A CB  1 
ATOM   2659  C CG  . LEU A 1 348 ? 152.713 157.911 169.919 1.00 39.56  ? 369 LEU A CG  1 
ATOM   2660  C CD1 . LEU A 1 348 ? 152.856 156.516 170.501 1.00 39.56  ? 369 LEU A CD1 1 
ATOM   2661  C CD2 . LEU A 1 348 ? 152.993 157.903 168.425 1.00 39.56  ? 369 LEU A CD2 1 
ATOM   2662  N N   . TYR A 1 349 ? 149.421 161.166 171.431 1.00 36.40  ? 370 TYR A N   1 
ATOM   2663  C CA  . TYR A 1 349 ? 148.079 161.722 171.488 1.00 36.40  ? 370 TYR A CA  1 
ATOM   2664  C C   . TYR A 1 349 ? 148.094 162.942 172.394 1.00 36.40  ? 370 TYR A C   1 
ATOM   2665  O O   . TYR A 1 349 ? 148.978 163.100 173.239 1.00 36.40  ? 370 TYR A O   1 
ATOM   2666  C CB  . TYR A 1 349 ? 147.054 160.693 171.988 1.00 36.40  ? 370 TYR A CB  1 
ATOM   2667  C CG  . TYR A 1 349 ? 147.095 160.428 173.480 1.00 36.40  ? 370 TYR A CG  1 
ATOM   2668  C CD1 . TYR A 1 349 ? 148.089 159.632 174.037 1.00 36.40  ? 370 TYR A CD1 1 
ATOM   2669  C CD2 . TYR A 1 349 ? 146.126 160.960 174.329 1.00 36.40  ? 370 TYR A CD2 1 
ATOM   2670  C CE1 . TYR A 1 349 ? 148.126 159.382 175.397 1.00 36.40  ? 370 TYR A CE1 1 
ATOM   2671  C CE2 . TYR A 1 349 ? 146.159 160.718 175.691 1.00 36.40  ? 370 TYR A CE2 1 
ATOM   2672  C CZ  . TYR A 1 349 ? 147.160 159.929 176.217 1.00 36.40  ? 370 TYR A CZ  1 
ATOM   2673  O OH  . TYR A 1 349 ? 147.195 159.683 177.568 1.00 36.40  ? 370 TYR A OH  1 
ATOM   2674  N N   . ALA A 1 350 ? 147.098 163.803 172.211 1.00 36.50  ? 371 ALA A N   1 
ATOM   2675  C CA  . ALA A 1 350 ? 146.918 164.955 173.086 1.00 36.50  ? 371 ALA A CA  1 
ATOM   2676  C C   . ALA A 1 350 ? 145.435 165.298 173.138 1.00 36.50  ? 371 ALA A C   1 
ATOM   2677  O O   . ALA A 1 350 ? 144.587 164.550 172.642 1.00 36.50  ? 371 ALA A O   1 
ATOM   2678  C CB  . ALA A 1 350 ? 147.768 166.142 172.619 1.00 36.50  ? 371 ALA A CB  1 
ATOM   2679  N N   . LEU A 1 351 ? 145.122 166.440 173.746 1.00 31.70  ? 372 LEU A N   1 
ATOM   2680  C CA  . LEU A 1 351 ? 143.745 166.871 173.934 1.00 31.70  ? 372 LEU A CA  1 
ATOM   2681  C C   . LEU A 1 351 ? 143.707 168.387 173.826 1.00 31.70  ? 372 LEU A C   1 
ATOM   2682  O O   . LEU A 1 351 ? 144.503 169.073 174.473 1.00 31.70  ? 372 LEU A O   1 
ATOM   2683  C CB  . LEU A 1 351 ? 143.210 166.403 175.296 1.00 31.70  ? 372 LEU A CB  1 
ATOM   2684  C CG  . LEU A 1 351 ? 141.714 166.423 175.632 1.00 31.70  ? 372 LEU A CG  1 
ATOM   2685  C CD1 . LEU A 1 351 ? 141.403 165.286 176.587 1.00 31.70  ? 372 LEU A CD1 1 
ATOM   2686  C CD2 . LEU A 1 351 ? 141.270 167.730 176.253 1.00 31.70  ? 372 LEU A CD2 1 
ATOM   2687  N N   . SER A 1 352 ? 142.793 168.906 173.009 1.00 40.84  ? 373 SER A N   1 
ATOM   2688  C CA  . SER A 1 352 ? 142.630 170.347 172.850 1.00 40.84  ? 373 SER A CA  1 
ATOM   2689  C C   . SER A 1 352 ? 141.151 170.661 172.695 1.00 40.84  ? 373 SER A C   1 
ATOM   2690  O O   . SER A 1 352 ? 140.523 170.198 171.737 1.00 40.84  ? 373 SER A O   1 
ATOM   2691  C CB  . SER A 1 352 ? 143.421 170.865 171.644 1.00 40.84  ? 373 SER A CB  1 
ATOM   2692  O OG  . SER A 1 352 ? 142.666 170.753 170.451 1.00 40.84  ? 373 SER A OG  1 
ATOM   2693  N N   . GLU A 1 353 ? 140.617 171.445 173.644 1.00 42.38  ? 374 GLU A N   1 
ATOM   2694  C CA  . GLU A 1 353 ? 139.221 171.912 173.669 1.00 42.38  ? 374 GLU A CA  1 
ATOM   2695  C C   . GLU A 1 353 ? 138.224 170.754 173.637 1.00 42.38  ? 374 GLU A C   1 
ATOM   2696  O O   . GLU A 1 353 ? 137.185 170.824 172.977 1.00 42.38  ? 374 GLU A O   1 
ATOM   2697  C CB  . GLU A 1 353 ? 138.942 172.901 172.533 1.00 42.38  ? 374 GLU A CB  1 
ATOM   2698  C CG  . GLU A 1 353 ? 139.585 174.262 172.725 1.00 42.38  ? 374 GLU A CG  1 
ATOM   2699  C CD  . GLU A 1 353 ? 140.940 174.363 172.055 1.00 42.38  ? 374 GLU A CD  1 
ATOM   2700  O OE1 . GLU A 1 353 ? 141.271 173.473 171.245 1.00 42.38  ? 374 GLU A OE1 1 
ATOM   2701  O OE2 . GLU A 1 353 ? 141.674 175.333 172.340 1.00 42.38  ? 374 GLU A OE2 1 
ATOM   2702  N N   . GLY A 1 354 ? 138.541 169.679 174.354 1.00 44.34  ? 375 GLY A N   1 
ATOM   2703  C CA  . GLY A 1 354 ? 137.713 168.491 174.331 1.00 44.34  ? 375 GLY A CA  1 
ATOM   2704  C C   . GLY A 1 354 ? 137.804 167.683 173.058 1.00 44.34  ? 375 GLY A C   1 
ATOM   2705  O O   . GLY A 1 354 ? 136.914 166.866 172.794 1.00 44.34  ? 375 GLY A O   1 
ATOM   2706  N N   . VAL A 1 355 ? 138.849 167.886 172.264 1.00 41.10  ? 376 VAL A N   1 
ATOM   2707  C CA  . VAL A 1 355 ? 139.021 167.241 170.970 1.00 41.10  ? 376 VAL A CA  1 
ATOM   2708  C C   . VAL A 1 355 ? 140.303 166.424 171.024 1.00 41.10  ? 376 VAL A C   1 
ATOM   2709  O O   . VAL A 1 355 ? 141.354 166.944 171.418 1.00 41.10  ? 376 VAL A O   1 
ATOM   2710  C CB  . VAL A 1 355 ? 139.074 168.283 169.837 1.00 41.10  ? 376 VAL A CB  1 
ATOM   2711  C CG1 . VAL A 1 355 ? 139.410 167.632 168.522 1.00 41.10  ? 376 VAL A CG1 1 
ATOM   2712  C CG2 . VAL A 1 355 ? 137.751 169.028 169.737 1.00 41.10  ? 376 VAL A CG2 1 
ATOM   2713  N N   . ILE A 1 356 ? 140.221 165.150 170.648 1.00 40.29  ? 377 ILE A N   1 
ATOM   2714  C CA  . ILE A 1 356 ? 141.376 164.260 170.694 1.00 40.29  ? 377 ILE A CA  1 
ATOM   2715  C C   . ILE A 1 356 ? 142.105 164.307 169.359 1.00 40.29  ? 377 ILE A C   1 
ATOM   2716  O O   . ILE A 1 356 ? 141.523 164.014 168.310 1.00 40.29  ? 377 ILE A O   1 
ATOM   2717  C CB  . ILE A 1 356 ? 140.959 162.824 171.045 1.00 40.29  ? 377 ILE A CB  1 
ATOM   2718  C CG1 . ILE A 1 356 ? 140.500 162.743 172.496 1.00 40.29  ? 377 ILE A CG1 1 
ATOM   2719  C CG2 . ILE A 1 356 ? 142.105 161.858 170.821 1.00 40.29  ? 377 ILE A CG2 1 
ATOM   2720  C CD1 . ILE A 1 356 ? 141.535 163.234 173.476 1.00 40.29  ? 377 ILE A CD1 1 
ATOM   2721  N N   . TYR A 1 357 ? 143.377 164.686 169.398 1.00 39.80  ? 378 TYR A N   1 
ATOM   2722  C CA  . TYR A 1 357 ? 144.286 164.519 168.272 1.00 39.80  ? 378 TYR A CA  1 
ATOM   2723  C C   . TYR A 1 357 ? 145.197 163.347 168.610 1.00 39.80  ? 378 TYR A C   1 
ATOM   2724  O O   . TYR A 1 357 ? 146.052 163.456 169.496 1.00 39.80  ? 378 TYR A O   1 
ATOM   2725  C CB  . TYR A 1 357 ? 145.091 165.791 168.017 1.00 39.80  ? 378 TYR A CB  1 
ATOM   2726  C CG  . TYR A 1 357 ? 144.272 166.967 167.537 1.00 39.80  ? 378 TYR A CG  1 
ATOM   2727  C CD1 . TYR A 1 357 ? 143.076 166.778 166.855 1.00 39.80  ? 378 TYR A CD1 1 
ATOM   2728  C CD2 . TYR A 1 357 ? 144.698 168.270 167.766 1.00 39.80  ? 378 TYR A CD2 1 
ATOM   2729  C CE1 . TYR A 1 357 ? 142.330 167.855 166.411 1.00 39.80  ? 378 TYR A CE1 1 
ATOM   2730  C CE2 . TYR A 1 357 ? 143.957 169.353 167.329 1.00 39.80  ? 378 TYR A CE2 1 
ATOM   2731  C CZ  . TYR A 1 357 ? 142.774 169.139 166.654 1.00 39.80  ? 378 TYR A CZ  1 
ATOM   2732  O OH  . TYR A 1 357 ? 142.034 170.212 166.218 1.00 39.80  ? 378 TYR A OH  1 
ATOM   2733  N N   . ALA A 1 358 ? 145.006 162.223 167.922 1.00 49.01  ? 379 ALA A N   1 
ATOM   2734  C CA  . ALA A 1 358 ? 145.733 161.009 168.262 1.00 49.01  ? 379 ALA A CA  1 
ATOM   2735  C C   . ALA A 1 358 ? 146.256 160.329 167.008 1.00 49.01  ? 379 ALA A C   1 
ATOM   2736  O O   . ALA A 1 358 ? 145.597 160.338 165.967 1.00 49.01  ? 379 ALA A O   1 
ATOM   2737  C CB  . ALA A 1 358 ? 144.850 160.029 169.041 1.00 49.01  ? 379 ALA A CB  1 
ATOM   2738  N N   . ASN A 1 359 ? 147.437 159.727 167.122 1.00 56.13  ? 380 ASN A N   1 
ATOM   2739  C CA  . ASN A 1 359 ? 147.999 158.900 166.058 1.00 56.13  ? 380 ASN A CA  1 
ATOM   2740  C C   . ASN A 1 359 ? 147.539 157.469 166.303 1.00 56.13  ? 380 ASN A C   1 
ATOM   2741  O O   . ASN A 1 359 ? 148.100 156.758 167.140 1.00 56.13  ? 380 ASN A O   1 
ATOM   2742  C CB  . ASN A 1 359 ? 149.519 159.006 166.030 1.00 56.13  ? 380 ASN A CB  1 
ATOM   2743  C CG  . ASN A 1 359 ? 150.118 158.467 164.746 1.00 56.13  ? 380 ASN A CG  1 
ATOM   2744  O OD1 . ASN A 1 359 ? 149.400 158.078 163.825 1.00 56.13  ? 380 ASN A OD1 1 
ATOM   2745  N ND2 . ASN A 1 359 ? 151.444 158.436 164.680 1.00 56.13  ? 380 ASN A ND2 1 
ATOM   2746  N N   . CYS A 1 360 ? 146.517 157.042 165.568 1.00 58.11  ? 381 CYS A N   1 
ATOM   2747  C CA  . CYS A 1 360 ? 145.901 155.741 165.785 1.00 58.11  ? 381 CYS A CA  1 
ATOM   2748  C C   . CYS A 1 360 ? 146.594 154.614 165.031 1.00 58.11  ? 381 CYS A C   1 
ATOM   2749  O O   . CYS A 1 360 ? 146.161 153.462 165.137 1.00 58.11  ? 381 CYS A O   1 
ATOM   2750  C CB  . CYS A 1 360 ? 144.421 155.789 165.397 1.00 58.11  ? 381 CYS A CB  1 
ATOM   2751  S SG  . CYS A 1 360 ? 143.410 156.779 166.519 1.00 58.11  ? 381 CYS A SG  1 
ATOM   2752  N N   . LEU A 1 361 ? 147.649 154.912 164.271 1.00 61.97  ? 382 LEU A N   1 
ATOM   2753  C CA  . LEU A 1 361 ? 148.390 153.854 163.594 1.00 61.97  ? 382 LEU A CA  1 
ATOM   2754  C C   . LEU A 1 361 ? 149.290 153.093 164.561 1.00 61.97  ? 382 LEU A C   1 
ATOM   2755  O O   . LEU A 1 361 ? 149.427 151.870 164.454 1.00 61.97  ? 382 LEU A O   1 
ATOM   2756  C CB  . LEU A 1 361 ? 149.212 154.440 162.446 1.00 61.97  ? 382 LEU A CB  1 
ATOM   2757  C CG  . LEU A 1 361 ? 149.880 153.436 161.503 1.00 61.97  ? 382 LEU A CG  1 
ATOM   2758  C CD1 . LEU A 1 361 ? 148.857 152.461 160.944 1.00 61.97  ? 382 LEU A CD1 1 
ATOM   2759  C CD2 . LEU A 1 361 ? 150.602 154.158 160.378 1.00 61.97  ? 382 LEU A CD2 1 
ATOM   2760  N N   . ALA A 1 362 ? 149.907 153.797 165.510 1.00 62.17  ? 383 ALA A N   1 
ATOM   2761  C CA  . ALA A 1 362 ? 150.814 153.168 166.463 1.00 62.17  ? 383 ALA A CA  1 
ATOM   2762  C C   . ALA A 1 362 ? 150.127 152.804 167.773 1.00 62.17  ? 383 ALA A C   1 
ATOM   2763  O O   . ALA A 1 362 ? 150.463 151.784 168.384 1.00 62.17  ? 383 ALA A O   1 
ATOM   2764  C CB  . ALA A 1 362 ? 152.006 154.088 166.740 1.00 62.17  ? 383 ALA A CB  1 
ATOM   2765  N N   . THR A 1 363 ? 149.175 153.617 168.218 1.00 59.38  ? 384 THR A N   1 
ATOM   2766  C CA  . THR A 1 363 ? 148.452 153.389 169.460 1.00 59.38  ? 384 THR A CA  1 
ATOM   2767  C C   . THR A 1 363 ? 147.023 152.973 169.136 1.00 59.38  ? 384 THR A C   1 
ATOM   2768  O O   . THR A 1 363 ? 146.397 153.534 168.232 1.00 59.38  ? 384 THR A O   1 
ATOM   2769  C CB  . THR A 1 363 ? 148.458 154.649 170.333 1.00 59.38  ? 384 THR A CB  1 
ATOM   2770  O OG1 . THR A 1 363 ? 149.790 155.169 170.405 1.00 59.38  ? 384 THR A OG1 1 
ATOM   2771  C CG2 . THR A 1 363 ? 147.983 154.340 171.747 1.00 59.38  ? 384 THR A CG2 1 
ATOM   2772  N N   . SER A 1 364 ? 146.521 151.973 169.860 1.00 64.28  ? 385 SER A N   1 
ATOM   2773  C CA  . SER A 1 364 ? 145.180 151.460 169.615 1.00 64.28  ? 385 SER A CA  1 
ATOM   2774  C C   . SER A 1 364 ? 144.123 152.477 170.034 1.00 64.28  ? 385 SER A C   1 
ATOM   2775  O O   . SER A 1 364 ? 144.156 153.002 171.151 1.00 64.28  ? 385 SER A O   1 
ATOM   2776  C CB  . SER A 1 364 ? 144.973 150.147 170.367 1.00 64.28  ? 385 SER A CB  1 
ATOM   2777  O OG  . SER A 1 364 ? 143.630 149.707 170.262 1.00 64.28  ? 385 SER A OG  1 
ATOM   2778  N N   . CYS A 1 365 ? 143.186 152.751 169.130 1.00 64.04  ? 386 CYS A N   1 
ATOM   2779  C CA  . CYS A 1 365 ? 142.079 153.663 169.379 1.00 64.04  ? 386 CYS A CA  1 
ATOM   2780  C C   . CYS A 1 365 ? 140.777 152.881 169.303 1.00 64.04  ? 386 CYS A C   1 
ATOM   2781  O O   . CYS A 1 365 ? 140.526 152.187 168.312 1.00 64.04  ? 386 CYS A O   1 
ATOM   2782  C CB  . CYS A 1 365 ? 142.059 154.804 168.359 1.00 64.04  ? 386 CYS A CB  1 
ATOM   2783  S SG  . CYS A 1 365 ? 143.553 155.812 168.300 1.00 64.04  ? 386 CYS A SG  1 
ATOM   2784  N N   . LYS A 1 366 ? 139.953 152.992 170.341 1.00 65.98  ? 387 LYS A N   1 
ATOM   2785  C CA  . LYS A 1 366 ? 138.668 152.305 170.360 1.00 65.98  ? 387 LYS A CA  1 
ATOM   2786  C C   . LYS A 1 366 ? 137.615 153.225 170.958 1.00 65.98  ? 387 LYS A C   1 
ATOM   2787  O O   . LYS A 1 366 ? 137.923 154.284 171.503 1.00 65.98  ? 387 LYS A O   1 
ATOM   2788  C CB  . LYS A 1 366 ? 138.737 150.994 171.152 1.00 65.98  ? 387 LYS A CB  1 
ATOM   2789  C CG  . LYS A 1 366 ? 139.161 149.782 170.333 1.00 65.98  ? 387 LYS A CG  1 
ATOM   2790  C CD  . LYS A 1 366 ? 139.466 148.562 171.205 1.00 65.98  ? 387 LYS A CD  1 
ATOM   2791  C CE  . LYS A 1 366 ? 138.440 148.361 172.318 1.00 65.98  ? 387 LYS A CE  1 
ATOM   2792  N NZ  . LYS A 1 366 ? 137.104 147.982 171.781 1.00 65.98  ? 387 LYS A NZ  1 
ATOM   2793  N N   . CYS A 1 367 ? 136.359 152.802 170.866 1.00 73.72  ? 388 CYS A N   1 
ATOM   2794  C CA  . CYS A 1 367 ? 135.247 153.501 171.495 1.00 73.72  ? 388 CYS A CA  1 
ATOM   2795  C C   . CYS A 1 367 ? 134.622 152.594 172.544 1.00 73.72  ? 388 CYS A C   1 
ATOM   2796  O O   . CYS A 1 367 ? 134.262 151.453 172.244 1.00 73.72  ? 388 CYS A O   1 
ATOM   2797  C CB  . CYS A 1 367 ? 134.207 153.927 170.460 1.00 73.72  ? 388 CYS A CB  1 
ATOM   2798  S SG  . CYS A 1 367 ? 134.865 155.024 169.188 1.00 73.72  ? 388 CYS A SG  1 
ATOM   2799  N N   . ALA A 1 368 ? 134.498 153.103 173.770 1.00 73.79  ? 389 ALA A N   1 
ATOM   2800  C CA  . ALA A 1 368 ? 134.009 152.280 174.871 1.00 73.79  ? 389 ALA A CA  1 
ATOM   2801  C C   . ALA A 1 368 ? 132.504 152.050 174.805 1.00 73.79  ? 389 ALA A C   1 
ATOM   2802  O O   . ALA A 1 368 ? 132.021 151.018 175.281 1.00 73.79  ? 389 ALA A O   1 
ATOM   2803  C CB  . ALA A 1 368 ? 134.380 152.918 176.209 1.00 73.79  ? 389 ALA A CB  1 
ATOM   2804  N N   . THR A 1 369 ? 131.752 152.990 174.231 1.00 73.22  ? 390 THR A N   1 
ATOM   2805  C CA  . THR A 1 369 ? 130.300 152.858 174.189 1.00 73.22  ? 390 THR A CA  1 
ATOM   2806  C C   . THR A 1 369 ? 129.837 151.845 173.150 1.00 73.22  ? 390 THR A C   1 
ATOM   2807  O O   . THR A 1 369 ? 128.814 151.182 173.354 1.00 73.22  ? 390 THR A O   1 
ATOM   2808  C CB  . THR A 1 369 ? 129.653 154.215 173.908 1.00 73.22  ? 390 THR A CB  1 
ATOM   2809  O OG1 . THR A 1 369 ? 130.240 154.791 172.734 1.00 73.22  ? 390 THR A OG1 1 
ATOM   2810  C CG2 . THR A 1 369 ? 129.854 155.153 175.086 1.00 73.22  ? 390 THR A CG2 1 
ATOM   2811  N N   . THR A 1 370 ? 130.565 151.707 172.041 1.00 70.50  ? 391 THR A N   1 
ATOM   2812  C CA  . THR A 1 370 ? 130.152 150.835 170.951 1.00 70.50  ? 391 THR A CA  1 
ATOM   2813  C C   . THR A 1 370 ? 131.008 149.587 170.798 1.00 70.50  ? 391 THR A C   1 
ATOM   2814  O O   . THR A 1 370 ? 130.551 148.631 170.162 1.00 70.50  ? 391 THR A O   1 
ATOM   2815  C CB  . THR A 1 370 ? 130.167 151.603 169.622 1.00 70.50  ? 391 THR A CB  1 
ATOM   2816  O OG1 . THR A 1 370 ? 131.455 152.199 169.432 1.00 70.50  ? 391 THR A OG1 1 
ATOM   2817  C CG2 . THR A 1 370 ? 129.106 152.692 169.625 1.00 70.50  ? 391 THR A CG2 1 
ATOM   2818  N N   . ASN A 1 371 ? 132.224 149.587 171.360 1.00 64.38  ? 392 ASN A N   1 
ATOM   2819  C CA  . ASN A 1 371 ? 133.185 148.476 171.328 1.00 64.38  ? 392 ASN A CA  1 
ATOM   2820  C C   . ASN A 1 371 ? 133.528 148.073 169.889 1.00 64.38  ? 392 ASN A C   1 
ATOM   2821  O O   . ASN A 1 371 ? 133.260 146.958 169.437 1.00 64.38  ? 392 ASN A O   1 
ATOM   2822  C CB  . ASN A 1 371 ? 132.684 147.281 172.153 1.00 64.38  ? 392 ASN A CB  1 
ATOM   2823  C CG  . ASN A 1 371 ? 133.770 146.255 172.416 1.00 64.38  ? 392 ASN A CG  1 
ATOM   2824  O OD1 . ASN A 1 371 ? 134.935 146.603 172.605 1.00 64.38  ? 392 ASN A OD1 1 
ATOM   2825  N ND2 . ASN A 1 371 ? 133.391 144.983 172.432 1.00 64.38  ? 392 ASN A ND2 1 
ATOM   2826  N N   . LYS A 1 372 ? 134.112 149.022 169.164 1.00 66.07  ? 393 LYS A N   1 
ATOM   2827  C CA  . LYS A 1 372 ? 134.624 148.780 167.825 1.00 66.07  ? 393 LYS A CA  1 
ATOM   2828  C C   . LYS A 1 372 ? 135.966 149.482 167.676 1.00 66.07  ? 393 LYS A C   1 
ATOM   2829  O O   . LYS A 1 372 ? 136.178 150.549 168.264 1.00 66.07  ? 393 LYS A O   1 
ATOM   2830  C CB  . LYS A 1 372 ? 133.653 149.269 166.736 1.00 66.07  ? 393 LYS A CB  1 
ATOM   2831  C CG  . LYS A 1 372 ? 133.181 150.706 166.881 1.00 66.07  ? 393 LYS A CG  1 
ATOM   2832  C CD  . LYS A 1 372 ? 132.086 151.017 165.871 1.00 66.07  ? 393 LYS A CD  1 
ATOM   2833  C CE  . LYS A 1 372 ? 131.465 152.382 166.118 1.00 66.07  ? 393 LYS A CE  1 
ATOM   2834  N NZ  . LYS A 1 372 ? 132.458 153.480 165.959 1.00 66.07  ? 393 LYS A NZ  1 
ATOM   2835  N N   . PRO A 1 373 ? 136.895 148.901 166.919 1.00 64.58  ? 394 PRO A N   1 
ATOM   2836  C CA  . PRO A 1 373 ? 138.179 149.569 166.693 1.00 64.58  ? 394 PRO A CA  1 
ATOM   2837  C C   . PRO A 1 373 ? 138.050 150.726 165.715 1.00 64.58  ? 394 PRO A C   1 
ATOM   2838  O O   . PRO A 1 373 ? 137.115 150.808 164.915 1.00 64.58  ? 394 PRO A O   1 
ATOM   2839  C CB  . PRO A 1 373 ? 139.064 148.458 166.122 1.00 64.58  ? 394 PRO A CB  1 
ATOM   2840  C CG  . PRO A 1 373 ? 138.107 147.515 165.490 1.00 64.58  ? 394 PRO A CG  1 
ATOM   2841  C CD  . PRO A 1 373 ? 136.881 147.538 166.356 1.00 64.58  ? 394 PRO A CD  1 
ATOM   2842  N N   . ILE A 1 374 ? 139.020 151.633 165.794 1.00 69.61  ? 395 ILE A N   1 
ATOM   2843  C CA  . ILE A 1 374 ? 139.115 152.784 164.905 1.00 69.61  ? 395 ILE A CA  1 
ATOM   2844  C C   . ILE A 1 374 ? 140.346 152.603 164.030 1.00 69.61  ? 395 ILE A C   1 
ATOM   2845  O O   . ILE A 1 374 ? 141.450 152.379 164.541 1.00 69.61  ? 395 ILE A O   1 
ATOM   2846  C CB  . ILE A 1 374 ? 139.184 154.105 165.690 1.00 69.61  ? 395 ILE A CB  1 
ATOM   2847  C CG1 . ILE A 1 374 ? 138.130 154.123 166.799 1.00 69.61  ? 395 ILE A CG1 1 
ATOM   2848  C CG2 . ILE A 1 374 ? 138.997 155.289 164.755 1.00 69.61  ? 395 ILE A CG2 1 
ATOM   2849  C CD1 . ILE A 1 374 ? 138.349 155.203 167.832 1.00 69.61  ? 395 ILE A CD1 1 
ATOM   2850  N N   . VAL A 1 375 ? 140.157 152.702 162.719 1.00 75.74  ? 396 VAL A N   1 
ATOM   2851  C CA  . VAL A 1 375 ? 141.212 152.435 161.751 1.00 75.74  ? 396 VAL A CA  1 
ATOM   2852  C C   . VAL A 1 375 ? 141.659 153.761 161.143 1.00 75.74  ? 396 VAL A C   1 
ATOM   2853  O O   . VAL A 1 375 ? 140.886 154.724 161.057 1.00 75.74  ? 396 VAL A O   1 
ATOM   2854  C CB  . VAL A 1 375 ? 140.722 151.418 160.685 1.00 75.74  ? 396 VAL A CB  1 
ATOM   2855  C CG1 . VAL A 1 375 ? 139.603 151.995 159.814 1.00 75.74  ? 396 VAL A CG1 1 
ATOM   2856  C CG2 . VAL A 1 375 ? 141.871 150.844 159.846 1.00 75.74  ? 396 VAL A CG2 1 
ATOM   2857  N N   . GLN A 1 376 ? 142.941 153.829 160.782 1.00 71.32  ? 397 GLN A N   1 
ATOM   2858  C CA  . GLN A 1 376 ? 143.494 155.021 160.155 1.00 71.32  ? 397 GLN A CA  1 
ATOM   2859  C C   . GLN A 1 376 ? 142.943 155.190 158.746 1.00 71.32  ? 397 GLN A C   1 
ATOM   2860  O O   . GLN A 1 376 ? 142.973 154.256 157.939 1.00 71.32  ? 397 GLN A O   1 
ATOM   2861  C CB  . GLN A 1 376 ? 145.018 154.928 160.103 1.00 71.32  ? 397 GLN A CB  1 
ATOM   2862  C CG  . GLN A 1 376 ? 145.726 155.330 161.379 1.00 71.32  ? 397 GLN A CG  1 
ATOM   2863  C CD  . GLN A 1 376 ? 145.718 156.826 161.598 1.00 71.32  ? 397 GLN A CD  1 
ATOM   2864  O OE1 . GLN A 1 376 ? 145.030 157.330 162.482 1.00 71.32  ? 397 GLN A OE1 1 
ATOM   2865  N NE2 . GLN A 1 376 ? 146.483 157.548 160.787 1.00 71.32  ? 397 GLN A NE2 1 
ATOM   2866  N N   . SER A 1 377 ? 142.438 156.384 158.450 1.00 77.27  ? 398 SER A N   1 
ATOM   2867  C CA  . SER A 1 377 ? 142.081 156.715 157.080 1.00 77.27  ? 398 SER A CA  1 
ATOM   2868  C C   . SER A 1 377 ? 143.345 156.958 156.266 1.00 77.27  ? 398 SER A C   1 
ATOM   2869  O O   . SER A 1 377 ? 144.342 157.471 156.780 1.00 77.27  ? 398 SER A O   1 
ATOM   2870  C CB  . SER A 1 377 ? 141.178 157.947 157.042 1.00 77.27  ? 398 SER A CB  1 
ATOM   2871  O OG  . SER A 1 377 ? 140.874 158.314 155.707 1.00 77.27  ? 398 SER A OG  1 
ATOM   2872  N N   . THR A 1 378 ? 143.306 156.573 154.989 1.00 78.10  ? 399 THR A N   1 
ATOM   2873  C CA  . THR A 1 378 ? 144.474 156.742 154.133 1.00 78.10  ? 399 THR A CA  1 
ATOM   2874  C C   . THR A 1 378 ? 144.705 158.195 153.741 1.00 78.10  ? 399 THR A C   1 
ATOM   2875  O O   . THR A 1 378 ? 145.835 158.559 153.399 1.00 78.10  ? 399 THR A O   1 
ATOM   2876  C CB  . THR A 1 378 ? 144.336 155.885 152.875 1.00 78.10  ? 399 THR A CB  1 
ATOM   2877  O OG1 . THR A 1 378 ? 143.295 156.415 152.045 1.00 78.10  ? 399 THR A OG1 1 
ATOM   2878  C CG2 . THR A 1 378 ? 144.002 154.448 153.245 1.00 78.10  ? 399 THR A CG2 1 
ATOM   2879  N N   . SER A 1 379 ? 143.665 159.030 153.781 1.00 78.82  ? 400 SER A N   1 
ATOM   2880  C CA  . SER A 1 379 ? 143.814 160.429 153.400 1.00 78.82  ? 400 SER A CA  1 
ATOM   2881  C C   . SER A 1 379 ? 144.508 161.255 154.476 1.00 78.82  ? 400 SER A C   1 
ATOM   2882  O O   . SER A 1 379 ? 145.125 162.278 154.159 1.00 78.82  ? 400 SER A O   1 
ATOM   2883  C CB  . SER A 1 379 ? 142.446 161.034 153.080 1.00 78.82  ? 400 SER A CB  1 
ATOM   2884  O OG  . SER A 1 379 ? 141.622 161.065 154.232 1.00 78.82  ? 400 SER A OG  1 
ATOM   2885  N N   . THR A 1 380 ? 144.424 160.840 155.737 1.00 76.04  ? 401 THR A N   1 
ATOM   2886  C CA  . THR A 1 380 ? 144.955 161.617 156.846 1.00 76.04  ? 401 THR A CA  1 
ATOM   2887  C C   . THR A 1 380 ? 146.045 160.841 157.575 1.00 76.04  ? 401 THR A C   1 
ATOM   2888  O O   . THR A 1 380 ? 146.194 159.627 157.413 1.00 76.04  ? 401 THR A O   1 
ATOM   2889  C CB  . THR A 1 380 ? 143.850 162.008 157.836 1.00 76.04  ? 401 THR A CB  1 
ATOM   2890  O OG1 . THR A 1 380 ? 144.402 162.837 158.867 1.00 76.04  ? 401 THR A OG1 1 
ATOM   2891  C CG2 . THR A 1 380 ? 143.230 160.771 158.465 1.00 76.04  ? 401 THR A CG2 1 
ATOM   2892  N N   . VAL A 1 381 ? 146.822 161.571 158.372 1.00 62.38  ? 402 VAL A N   1 
ATOM   2893  C CA  . VAL A 1 381 ? 147.868 160.989 159.197 1.00 62.38  ? 402 VAL A CA  1 
ATOM   2894  C C   . VAL A 1 381 ? 147.523 161.073 160.679 1.00 62.38  ? 402 VAL A C   1 
ATOM   2895  O O   . VAL A 1 381 ? 147.704 160.102 161.417 1.00 62.38  ? 402 VAL A O   1 
ATOM   2896  C CB  . VAL A 1 381 ? 149.231 161.658 158.912 1.00 62.38  ? 402 VAL A CB  1 
ATOM   2897  C CG1 . VAL A 1 381 ? 150.356 160.856 159.538 1.00 62.38  ? 402 VAL A CG1 1 
ATOM   2898  C CG2 . VAL A 1 381 ? 149.455 161.811 157.416 1.00 62.38  ? 402 VAL A CG2 1 
ATOM   2899  N N   . ILE A 1 382 ? 147.018 162.219 161.129 1.00 54.78  ? 403 ILE A N   1 
ATOM   2900  C CA  . ILE A 1 382 ? 146.642 162.433 162.522 1.00 54.78  ? 403 ILE A CA  1 
ATOM   2901  C C   . ILE A 1 382 ? 145.125 162.373 162.628 1.00 54.78  ? 403 ILE A C   1 
ATOM   2902  O O   . ILE A 1 382 ? 144.414 163.074 161.897 1.00 54.78  ? 403 ILE A O   1 
ATOM   2903  C CB  . ILE A 1 382 ? 147.182 163.776 163.043 1.00 54.78  ? 403 ILE A CB  1 
ATOM   2904  C CG1 . ILE A 1 382 ? 148.705 163.821 162.910 1.00 54.78  ? 403 ILE A CG1 1 
ATOM   2905  C CG2 . ILE A 1 382 ? 146.771 164.001 164.489 1.00 54.78  ? 403 ILE A CG2 1 
ATOM   2906  C CD1 . ILE A 1 382 ? 149.421 162.789 163.751 1.00 54.78  ? 403 ILE A CD1 1 
ATOM   2907  N N   . THR A 1 383 ? 144.629 161.536 163.535 1.00 51.42  ? 404 THR A N   1 
ATOM   2908  C CA  . THR A 1 383 ? 143.202 161.277 163.664 1.00 51.42  ? 404 THR A CA  1 
ATOM   2909  C C   . THR A 1 383 ? 142.553 162.275 164.615 1.00 51.42  ? 404 THR A C   1 
ATOM   2910  O O   . THR A 1 383 ? 143.006 162.453 165.754 1.00 51.42  ? 404 THR A O   1 
ATOM   2911  C CB  . THR A 1 383 ? 142.961 159.848 164.154 1.00 51.42  ? 404 THR A CB  1 
ATOM   2912  O OG1 . THR A 1 383 ? 143.574 158.927 163.247 1.00 51.42  ? 404 THR A OG1 1 
ATOM   2913  C CG2 . THR A 1 383 ? 141.472 159.545 164.235 1.00 51.42  ? 404 THR A CG2 1 
ATOM   2914  N N   . MET A 1 384 ? 141.497 162.926 164.130 1.00 46.44  ? 405 MET A N   1 
ATOM   2915  C CA  . MET A 1 384 ? 140.640 163.793 164.925 1.00 46.44  ? 405 MET A CA  1 
ATOM   2916  C C   . MET A 1 384 ? 139.501 162.958 165.497 1.00 46.44  ? 405 MET A C   1 
ATOM   2917  O O   . MET A 1 384 ? 138.873 162.177 164.776 1.00 46.44  ? 405 MET A O   1 
ATOM   2918  C CB  . MET A 1 384 ? 140.126 164.938 164.043 1.00 46.44  ? 405 MET A CB  1 
ATOM   2919  C CG  . MET A 1 384 ? 139.401 166.146 164.682 1.00 46.44  ? 405 MET A CG  1 
ATOM   2920  S SD  . MET A 1 384 ? 137.916 165.906 165.686 1.00 46.44  ? 405 MET A SD  1 
ATOM   2921  C CE  . MET A 1 384 ? 136.831 165.189 164.457 1.00 46.44  ? 405 MET A CE  1 
ATOM   2922  N N   . ILE A 1 385 ? 139.235 163.131 166.792 1.00 45.78  ? 406 ILE A N   1 
ATOM   2923  C CA  . ILE A 1 385 ? 138.164 162.427 167.487 1.00 45.78  ? 406 ILE A CA  1 
ATOM   2924  C C   . ILE A 1 385 ? 137.353 163.442 168.283 1.00 45.78  ? 406 ILE A C   1 
ATOM   2925  O O   . ILE A 1 385 ? 137.911 164.191 169.095 1.00 45.78  ? 406 ILE A O   1 
ATOM   2926  C CB  . ILE A 1 385 ? 138.712 161.320 168.412 1.00 45.78  ? 406 ILE A CB  1 
ATOM   2927  C CG1 . ILE A 1 385 ? 139.235 160.140 167.592 1.00 45.78  ? 406 ILE A CG1 1 
ATOM   2928  C CG2 . ILE A 1 385 ? 137.647 160.834 169.381 1.00 45.78  ? 406 ILE A CG2 1 
ATOM   2929  C CD1 . ILE A 1 385 ? 139.909 159.073 168.423 1.00 45.78  ? 406 ILE A CD1 1 
ATOM   2930  N N   . ASP A 1 386 ? 136.040 163.467 168.044 1.00 54.12  ? 407 ASP A N   1 
ATOM   2931  C CA  . ASP A 1 386 ? 135.120 164.309 168.797 1.00 54.12  ? 407 ASP A CA  1 
ATOM   2932  C C   . ASP A 1 386 ? 133.939 163.483 169.294 1.00 54.12  ? 407 ASP A C   1 
ATOM   2933  O O   . ASP A 1 386 ? 133.968 162.250 169.233 1.00 54.12  ? 407 ASP A O   1 
ATOM   2934  C CB  . ASP A 1 386 ? 134.627 165.480 167.945 1.00 54.12  ? 407 ASP A CB  1 
ATOM   2935  C CG  . ASP A 1 386 ? 134.031 165.034 166.622 1.00 54.12  ? 407 ASP A CG  1 
ATOM   2936  O OD1 . ASP A 1 386 ? 134.257 163.874 166.218 1.00 54.12  ? 407 ASP A OD1 1 
ATOM   2937  O OD2 . ASP A 1 386 ? 133.331 165.848 165.984 1.00 54.12  ? 407 ASP A OD2 1 
ATOM   2938  N N   . ASN A 1 387 ? 132.897 164.152 169.788 1.00 57.93  ? 408 ASN A N   1 
ATOM   2939  C CA  . ASN A 1 387 ? 131.704 163.463 170.265 1.00 57.93  ? 408 ASN A CA  1 
ATOM   2940  C C   . ASN A 1 387 ? 130.806 162.940 169.147 1.00 57.93  ? 408 ASN A C   1 
ATOM   2941  O O   . ASN A 1 387 ? 129.871 162.185 169.433 1.00 57.93  ? 408 ASN A O   1 
ATOM   2942  C CB  . ASN A 1 387 ? 130.926 164.375 171.229 1.00 57.93  ? 408 ASN A CB  1 
ATOM   2943  C CG  . ASN A 1 387 ? 130.448 165.689 170.591 1.00 57.93  ? 408 ASN A CG  1 
ATOM   2944  O OD1 . ASN A 1 387 ? 130.585 165.929 169.390 1.00 57.93  ? 408 ASN A OD1 1 
ATOM   2945  N ND2 . ASN A 1 387 ? 129.882 166.554 171.425 1.00 57.93  ? 408 ASN A ND2 1 
ATOM   2946  N N   . SER A 1 388 ? 131.054 163.336 167.896 1.00 57.43  ? 409 SER A N   1 
ATOM   2947  C CA  . SER A 1 388 ? 130.300 162.776 166.780 1.00 57.43  ? 409 SER A CA  1 
ATOM   2948  C C   . SER A 1 388 ? 130.679 161.322 166.524 1.00 57.43  ? 409 SER A C   1 
ATOM   2949  O O   . SER A 1 388 ? 129.834 160.530 166.092 1.00 57.43  ? 409 SER A O   1 
ATOM   2950  C CB  . SER A 1 388 ? 130.521 163.620 165.525 1.00 57.43  ? 409 SER A CB  1 
ATOM   2951  O OG  . SER A 1 388 ? 130.026 164.937 165.705 1.00 57.43  ? 409 SER A OG  1 
ATOM   2952  N N   . LYS A 1 389 ? 131.934 160.953 166.784 1.00 56.41  ? 410 LYS A N   1 
ATOM   2953  C CA  . LYS A 1 389 ? 132.356 159.570 166.591 1.00 56.41  ? 410 LYS A CA  1 
ATOM   2954  C C   . LYS A 1 389 ? 131.862 158.684 167.730 1.00 56.41  ? 410 LYS A C   1 
ATOM   2955  O O   . LYS A 1 389 ? 131.044 157.782 167.519 1.00 56.41  ? 410 LYS A O   1 
ATOM   2956  C CB  . LYS A 1 389 ? 133.882 159.499 166.481 1.00 56.41  ? 410 LYS A CB  1 
ATOM   2957  C CG  . LYS A 1 389 ? 134.477 160.358 165.375 1.00 56.41  ? 410 LYS A CG  1 
ATOM   2958  C CD  . LYS A 1 389 ? 134.250 159.752 164.002 1.00 56.41  ? 410 LYS A CD  1 
ATOM   2959  C CE  . LYS A 1 389 ? 135.002 160.530 162.933 1.00 56.41  ? 410 LYS A CE  1 
ATOM   2960  N NZ  . LYS A 1 389 ? 134.805 159.952 161.576 1.00 56.41  ? 410 LYS A NZ  1 
ATOM   2961  N N   . CYS A 1 390 ? 132.334 158.954 168.954 1.00 65.09  ? 411 CYS A N   1 
ATOM   2962  C CA  . CYS A 1 390 ? 131.983 158.199 170.152 1.00 65.09  ? 411 CYS A CA  1 
ATOM   2963  C C   . CYS A 1 390 ? 132.368 159.010 171.376 1.00 65.09  ? 411 CYS A C   1 
ATOM   2964  O O   . CYS A 1 390 ? 133.414 159.674 171.352 1.00 65.09  ? 411 CYS A O   1 
ATOM   2965  C CB  . CYS A 1 390 ? 132.675 156.831 170.176 1.00 65.09  ? 411 CYS A CB  1 
ATOM   2966  S SG  . CYS A 1 390 ? 134.459 156.875 169.915 1.00 65.09  ? 411 CYS A SG  1 
ATOM   2967  N N   . PRO A 1 391 ? 131.555 159.004 172.445 1.00 50.22  ? 412 PRO A N   1 
ATOM   2968  C CA  . PRO A 1 391 ? 131.859 159.834 173.621 1.00 50.22  ? 412 PRO A CA  1 
ATOM   2969  C C   . PRO A 1 391 ? 133.077 159.383 174.415 1.00 50.22  ? 412 PRO A C   1 
ATOM   2970  O O   . PRO A 1 391 ? 133.967 160.189 174.701 1.00 50.22  ? 412 PRO A O   1 
ATOM   2971  C CB  . PRO A 1 391 ? 130.582 159.717 174.467 1.00 50.22  ? 412 PRO A CB  1 
ATOM   2972  C CG  . PRO A 1 391 ? 129.522 159.267 173.509 1.00 50.22  ? 412 PRO A CG  1 
ATOM   2973  C CD  . PRO A 1 391 ? 130.237 158.360 172.563 1.00 50.22  ? 412 PRO A CD  1 
ATOM   2974  N N   . VAL A 1 392 ? 133.131 158.107 174.778 1.00 52.35  ? 413 VAL A N   1 
ATOM   2975  C CA  . VAL A 1 392 ? 134.186 157.580 175.636 1.00 52.35  ? 413 VAL A CA  1 
ATOM   2976  C C   . VAL A 1 392 ? 135.167 156.813 174.761 1.00 52.35  ? 413 VAL A C   1 
ATOM   2977  O O   . VAL A 1 392 ? 134.792 155.840 174.098 1.00 52.35  ? 413 VAL A O   1 
ATOM   2978  C CB  . VAL A 1 392 ? 133.613 156.688 176.746 1.00 52.35  ? 413 VAL A CB  1 
ATOM   2979  C CG1 . VAL A 1 392 ? 134.688 156.360 177.758 1.00 52.35  ? 413 VAL A CG1 1 
ATOM   2980  C CG2 . VAL A 1 392 ? 132.432 157.373 177.415 1.00 52.35  ? 413 VAL A CG2 1 
ATOM   2981  N N   . VAL A 1 393 ? 136.425 157.249 174.762 1.00 44.95  ? 414 VAL A N   1 
ATOM   2982  C CA  . VAL A 1 393 ? 137.428 156.786 173.814 1.00 44.95  ? 414 VAL A CA  1 
ATOM   2983  C C   . VAL A 1 393 ? 138.524 156.053 174.577 1.00 44.95  ? 414 VAL A C   1 
ATOM   2984  O O   . VAL A 1 393 ? 139.102 156.601 175.525 1.00 44.95  ? 414 VAL A O   1 
ATOM   2985  C CB  . VAL A 1 393 ? 138.013 157.960 173.006 1.00 44.95  ? 414 VAL A CB  1 
ATOM   2986  C CG1 . VAL A 1 393 ? 138.869 157.452 171.866 1.00 44.95  ? 414 VAL A CG1 1 
ATOM   2987  C CG2 . VAL A 1 393 ? 136.905 158.861 172.486 1.00 44.95  ? 414 VAL A CG2 1 
ATOM   2988  N N   . GLU A 1 394 ? 138.781 154.808 174.177 1.00 63.17  ? 415 GLU A N   1 
ATOM   2989  C CA  . GLU A 1 394 ? 139.936 154.036 174.623 1.00 63.17  ? 415 GLU A CA  1 
ATOM   2990  C C   . GLU A 1 394 ? 141.153 154.533 173.854 1.00 63.17  ? 415 GLU A C   1 
ATOM   2991  O O   . GLU A 1 394 ? 141.252 154.321 172.638 1.00 63.17  ? 415 GLU A O   1 
ATOM   2992  C CB  . GLU A 1 394 ? 139.702 152.547 174.368 1.00 63.17  ? 415 GLU A CB  1 
ATOM   2993  C CG  . GLU A 1 394 ? 140.939 151.636 174.459 1.00 63.17  ? 415 GLU A CG  1 
ATOM   2994  C CD  . GLU A 1 394 ? 141.274 151.182 175.865 1.00 63.17  ? 415 GLU A CD  1 
ATOM   2995  O OE1 . GLU A 1 394 ? 140.344 150.989 176.664 1.00 63.17  ? 415 GLU A OE1 1 
ATOM   2996  O OE2 . GLU A 1 394 ? 142.469 151.013 176.174 1.00 63.17  ? 415 GLU A OE2 1 
ATOM   2997  N N   . VAL A 1 395 ? 142.059 155.224 174.545 1.00 52.65  ? 416 VAL A N   1 
ATOM   2998  C CA  . VAL A 1 395 ? 143.334 155.650 173.972 1.00 52.65  ? 416 VAL A CA  1 
ATOM   2999  C C   . VAL A 1 395 ? 144.434 155.189 174.915 1.00 52.65  ? 416 VAL A C   1 
ATOM   3000  O O   . VAL A 1 395 ? 144.429 155.548 176.099 1.00 52.65  ? 416 VAL A O   1 
ATOM   3001  C CB  . VAL A 1 395 ? 143.403 157.172 173.751 1.00 52.65  ? 416 VAL A CB  1 
ATOM   3002  C CG1 . VAL A 1 395 ? 144.830 157.611 173.463 1.00 52.65  ? 416 VAL A CG1 1 
ATOM   3003  C CG2 . VAL A 1 395 ? 142.509 157.581 172.600 1.00 52.65  ? 416 VAL A CG2 1 
ATOM   3004  N N   . GLY A 1 396 ? 145.379 154.410 174.391 1.00 55.37  ? 417 GLY A N   1 
ATOM   3005  C CA  . GLY A 1 396 ? 146.375 153.769 175.224 1.00 55.37  ? 417 GLY A CA  1 
ATOM   3006  C C   . GLY A 1 396 ? 145.721 152.724 176.100 1.00 55.37  ? 417 GLY A C   1 
ATOM   3007  O O   . GLY A 1 396 ? 145.186 151.737 175.594 1.00 55.37  ? 417 GLY A O   1 
ATOM   3008  N N   . LYS A 1 397 ? 145.748 152.943 177.415 1.00 60.50  ? 418 LYS A N   1 
ATOM   3009  C CA  . LYS A 1 397 ? 144.975 152.168 178.378 1.00 60.50  ? 418 LYS A CA  1 
ATOM   3010  C C   . LYS A 1 397 ? 143.920 153.022 179.076 1.00 60.50  ? 418 LYS A C   1 
ATOM   3011  O O   . LYS A 1 397 ? 143.403 152.627 180.126 1.00 60.50  ? 418 LYS A O   1 
ATOM   3012  C CB  . LYS A 1 397 ? 145.897 151.533 179.424 1.00 60.50  ? 418 LYS A CB  1 
ATOM   3013  C CG  . LYS A 1 397 ? 146.973 150.528 178.956 1.00 60.50  ? 418 LYS A CG  1 
ATOM   3014  C CD  . LYS A 1 397 ? 146.434 149.152 178.522 1.00 60.50  ? 418 LYS A CD  1 
ATOM   3015  C CE  . LYS A 1 397 ? 146.211 149.002 177.021 1.00 60.50  ? 418 LYS A CE  1 
ATOM   3016  N NZ  . LYS A 1 397 ? 145.791 147.623 176.644 1.00 60.50  ? 418 LYS A NZ  1 
ATOM   3017  N N   . GLN A 1 398 ? 143.589 154.184 178.515 1.00 53.15  ? 419 GLN A N   1 
ATOM   3018  C CA  . GLN A 1 398 ? 142.857 155.221 179.229 1.00 53.15  ? 419 GLN A CA  1 
ATOM   3019  C C   . GLN A 1 398 ? 141.485 155.483 178.622 1.00 53.15  ? 419 GLN A C   1 
ATOM   3020  O O   . GLN A 1 398 ? 141.322 155.497 177.394 1.00 53.15  ? 419 GLN A O   1 
ATOM   3021  C CB  . GLN A 1 398 ? 143.651 156.531 179.248 1.00 53.15  ? 419 GLN A CB  1 
ATOM   3022  C CG  . GLN A 1 398 ? 145.126 156.367 179.548 1.00 53.15  ? 419 GLN A CG  1 
ATOM   3023  C CD  . GLN A 1 398 ? 145.401 156.248 181.032 1.00 53.15  ? 419 GLN A CD  1 
ATOM   3024  O OE1 . GLN A 1 398 ? 144.520 156.483 181.859 1.00 53.15  ? 419 GLN A OE1 1 
ATOM   3025  N NE2 . GLN A 1 398 ? 146.631 155.886 181.379 1.00 53.15  ? 419 GLN A NE2 1 
ATOM   3026  N N   . MET A 1 399 ? 140.508 155.689 179.504 1.00 50.61  ? 420 MET A N   1 
ATOM   3027  C CA  . MET A 1 399 ? 139.235 156.288 179.129 1.00 50.61  ? 420 MET A CA  1 
ATOM   3028  C C   . MET A 1 399 ? 139.411 157.793 178.990 1.00 50.61  ? 420 MET A C   1 
ATOM   3029  O O   . MET A 1 399 ? 139.973 158.440 179.877 1.00 50.61  ? 420 MET A O   1 
ATOM   3030  C CB  . MET A 1 399 ? 138.180 156.008 180.197 1.00 50.61  ? 420 MET A CB  1 
ATOM   3031  C CG  . MET A 1 399 ? 137.748 154.563 180.420 1.00 50.61  ? 420 MET A CG  1 
ATOM   3032  S SD  . MET A 1 399 ? 136.947 153.764 179.023 1.00 50.61  ? 420 MET A SD  1 
ATOM   3033  C CE  . MET A 1 399 ? 138.273 152.751 178.416 1.00 50.61  ? 420 MET A CE  1 
ATOM   3034  N N   . ILE A 1 400 ? 138.945 158.357 177.879 1.00 43.80  ? 421 ILE A N   1 
ATOM   3035  C CA  . ILE A 1 400 ? 138.886 159.805 177.714 1.00 43.80  ? 421 ILE A CA  1 
ATOM   3036  C C   . ILE A 1 400 ? 137.494 160.177 177.223 1.00 43.80  ? 421 ILE A C   1 
ATOM   3037  O O   . ILE A 1 400 ? 137.029 159.658 176.204 1.00 43.80  ? 421 ILE A O   1 
ATOM   3038  C CB  . ILE A 1 400 ? 139.966 160.323 176.735 1.00 43.80  ? 421 ILE A CB  1 
ATOM   3039  C CG1 . ILE A 1 400 ? 141.376 160.074 177.279 1.00 43.80  ? 421 ILE A CG1 1 
ATOM   3040  C CG2 . ILE A 1 400 ? 139.778 161.802 176.465 1.00 43.80  ? 421 ILE A CG2 1 
ATOM   3041  C CD1 . ILE A 1 400 ? 142.475 160.321 176.274 1.00 43.80  ? 421 ILE A CD1 1 
ATOM   3042  N N   . SER A 1 401 ? 136.819 161.061 177.953 1.00 40.11  ? 422 SER A N   1 
ATOM   3043  C CA  . SER A 1 401 ? 135.587 161.661 177.464 1.00 40.11  ? 422 SER A CA  1 
ATOM   3044  C C   . SER A 1 401 ? 135.909 162.887 176.625 1.00 40.11  ? 422 SER A C   1 
ATOM   3045  O O   . SER A 1 401 ? 136.863 163.619 176.897 1.00 40.11  ? 422 SER A O   1 
ATOM   3046  C CB  . SER A 1 401 ? 134.644 162.052 178.603 1.00 40.11  ? 422 SER A CB  1 
ATOM   3047  O OG  . SER A 1 401 ? 134.139 160.910 179.265 1.00 40.11  ? 422 SER A OG  1 
ATOM   3048  N N   . VAL A 1 402 ? 135.106 163.095 175.588 1.00 44.57  ? 423 VAL A N   1 
ATOM   3049  C CA  . VAL A 1 402 ? 135.292 164.219 174.682 1.00 44.57  ? 423 VAL A CA  1 
ATOM   3050  C C   . VAL A 1 402 ? 134.054 165.100 174.724 1.00 44.57  ? 423 VAL A C   1 
ATOM   3051  O O   . VAL A 1 402 ? 133.089 164.804 175.437 1.00 44.57  ? 423 VAL A O   1 
ATOM   3052  C CB  . VAL A 1 402 ? 135.578 163.738 173.251 1.00 44.57  ? 423 VAL A CB  1 
ATOM   3053  C CG1 . VAL A 1 402 ? 136.864 162.943 173.209 1.00 44.57  ? 423 VAL A CG1 1 
ATOM   3054  C CG2 . VAL A 1 402 ? 134.431 162.890 172.763 1.00 44.57  ? 423 VAL A CG2 1 
ATOM   3055  N N   . GLY A 1 403 ? 134.076 166.185 173.965 1.00 59.28  ? 424 GLY A N   1 
ATOM   3056  C CA  . GLY A 1 403 ? 132.950 167.092 173.949 1.00 59.28  ? 424 GLY A CA  1 
ATOM   3057  C C   . GLY A 1 403 ? 133.215 168.252 173.021 1.00 59.28  ? 424 GLY A C   1 
ATOM   3058  O O   . GLY A 1 403 ? 134.046 168.158 172.114 1.00 59.28  ? 424 GLY A O   1 
ATOM   3059  N N   . SER A 1 404 ? 132.494 169.342 173.274 1.00 78.59  ? 425 SER A N   1 
ATOM   3060  C CA  . SER A 1 404 ? 132.525 170.618 172.526 1.00 78.59  ? 425 SER A CA  1 
ATOM   3061  C C   . SER A 1 404 ? 132.166 170.310 171.069 1.00 78.59  ? 425 SER A C   1 
ATOM   3062  O O   . SER A 1 404 ? 131.270 169.490 170.815 1.00 78.59  ? 425 SER A O   1 
ATOM   3063  C CB  . SER A 1 404 ? 133.857 171.323 172.729 1.00 78.59  ? 425 SER A CB  1 
ATOM   3064  O OG  . SER A 1 404 ? 133.930 172.510 171.959 1.00 78.59  ? 425 SER A OG  1 
ATOM   3065  N N   . TYR A 1 405 ? 132.833 170.930 170.102 1.00 92.69  ? 426 TYR A N   1 
ATOM   3066  C CA  . TYR A 1 405 ? 132.593 170.637 168.698 1.00 92.69  ? 426 TYR A CA  1 
ATOM   3067  C C   . TYR A 1 405 ? 133.938 170.656 167.978 1.00 92.69  ? 426 TYR A C   1 
ATOM   3068  O O   . TYR A 1 405 ? 134.994 170.831 168.594 1.00 92.69  ? 426 TYR A O   1 
ATOM   3069  C CB  . TYR A 1 405 ? 131.556 171.611 168.117 1.00 92.69  ? 426 TYR A CB  1 
ATOM   3070  C CG  . TYR A 1 405 ? 132.097 172.945 167.655 1.00 92.69  ? 426 TYR A CG  1 
ATOM   3071  C CD1 . TYR A 1 405 ? 132.130 173.268 166.302 1.00 92.69  ? 426 TYR A CD1 1 
ATOM   3072  C CD2 . TYR A 1 405 ? 132.567 173.884 168.567 1.00 92.69  ? 426 TYR A CD2 1 
ATOM   3073  C CE1 . TYR A 1 405 ? 132.612 174.489 165.870 1.00 92.69  ? 426 TYR A CE1 1 
ATOM   3074  C CE2 . TYR A 1 405 ? 133.058 175.108 168.144 1.00 92.69  ? 426 TYR A CE2 1 
ATOM   3075  C CZ  . TYR A 1 405 ? 133.080 175.402 166.794 1.00 92.69  ? 426 TYR A CZ  1 
ATOM   3076  O OH  . TYR A 1 405 ? 133.565 176.616 166.366 1.00 92.69  ? 426 TYR A OH  1 
ATOM   3077  N N   . LEU A 1 406 ? 133.894 170.468 166.660 1.00 90.04  ? 427 LEU A N   1 
ATOM   3078  C CA  . LEU A 1 406 ? 135.109 170.223 165.890 1.00 90.04  ? 427 LEU A CA  1 
ATOM   3079  C C   . LEU A 1 406 ? 135.888 171.514 165.653 1.00 90.04  ? 427 LEU A C   1 
ATOM   3080  O O   . LEU A 1 406 ? 137.066 171.618 166.015 1.00 90.04  ? 427 LEU A O   1 
ATOM   3081  C CB  . LEU A 1 406 ? 134.732 169.547 164.571 1.00 90.04  ? 427 LEU A CB  1 
ATOM   3082  C CG  . LEU A 1 406 ? 135.631 169.480 163.339 1.00 90.04  ? 427 LEU A CG  1 
ATOM   3083  C CD1 . LEU A 1 406 ? 137.011 168.899 163.636 1.00 90.04  ? 427 LEU A CD1 1 
ATOM   3084  C CD2 . LEU A 1 406 ? 134.908 168.651 162.299 1.00 90.04  ? 427 LEU A CD2 1 
ATOM   3085  N N   . GLY A 1 407 ? 135.252 172.506 165.038 1.00 95.85  ? 428 GLY A N   1 
ATOM   3086  C CA  . GLY A 1 407 ? 135.921 173.758 164.741 1.00 95.85  ? 428 GLY A CA  1 
ATOM   3087  C C   . GLY A 1 407 ? 136.205 173.953 163.267 1.00 95.85  ? 428 GLY A C   1 
ATOM   3088  O O   . GLY A 1 407 ? 137.198 173.426 162.751 1.00 95.85  ? 428 GLY A O   1 
ATOM   3089  N N   . GLN A 1 408 ? 135.331 174.719 162.599 1.00 99.62  ? 429 GLN A N   1 
ATOM   3090  C CA  . GLN A 1 408 ? 135.384 175.053 161.175 1.00 99.62  ? 429 GLN A CA  1 
ATOM   3091  C C   . GLN A 1 408 ? 135.444 173.817 160.284 1.00 99.62  ? 429 GLN A C   1 
ATOM   3092  O O   . GLN A 1 408 ? 134.411 173.215 159.974 1.00 99.62  ? 429 GLN A O   1 
ATOM   3093  C CB  . GLN A 1 408 ? 136.570 175.985 160.878 1.00 99.62  ? 429 GLN A CB  1 
ATOM   3094  C CG  . GLN A 1 408 ? 136.607 177.343 161.626 1.00 99.62  ? 429 GLN A CG  1 
ATOM   3095  C CD  . GLN A 1 408 ? 135.302 178.160 161.648 1.00 99.62  ? 429 GLN A CD  1 
ATOM   3096  O OE1 . GLN A 1 408 ? 134.452 178.073 160.755 1.00 99.62  ? 429 GLN A OE1 1 
ATOM   3097  N NE2 . GLN A 1 408 ? 135.151 178.965 162.692 1.00 99.62  ? 429 GLN A NE2 1 
ATOM   3098  N N   . VAL A 1 409 ? 136.649 173.435 159.867 1.00 102.57 ? 430 VAL A N   1 
ATOM   3099  C CA  . VAL A 1 409 ? 136.852 172.258 159.037 1.00 102.57 ? 430 VAL A CA  1 
ATOM   3100  C C   . VAL A 1 409 ? 137.700 171.259 159.813 1.00 102.57 ? 430 VAL A C   1 
ATOM   3101  O O   . VAL A 1 409 ? 138.434 171.611 160.740 1.00 102.57 ? 430 VAL A O   1 
ATOM   3102  C CB  . VAL A 1 409 ? 137.508 172.602 157.683 1.00 102.57 ? 430 VAL A CB  1 
ATOM   3103  C CG1 . VAL A 1 409 ? 136.585 173.485 156.858 1.00 102.57 ? 430 VAL A CG1 1 
ATOM   3104  C CG2 . VAL A 1 409 ? 138.849 173.286 157.895 1.00 102.57 ? 430 VAL A CG2 1 
ATOM   3105  N N   . SER A 1 410 ? 137.572 169.992 159.437 1.00 104.45 ? 431 SER A N   1 
ATOM   3106  C CA  . SER A 1 410 ? 138.332 168.957 160.114 1.00 104.45 ? 431 SER A CA  1 
ATOM   3107  C C   . SER A 1 410 ? 139.730 168.831 159.514 1.00 104.45 ? 431 SER A C   1 
ATOM   3108  O O   . SER A 1 410 ? 139.925 169.069 158.319 1.00 104.45 ? 431 SER A O   1 
ATOM   3109  C CB  . SER A 1 410 ? 137.611 167.616 160.020 1.00 104.45 ? 431 SER A CB  1 
ATOM   3110  O OG  . SER A 1 410 ? 137.559 167.155 158.686 1.00 104.45 ? 431 SER A OG  1 
ATOM   3111  N N   . PRO A 1 411 ? 140.724 168.458 160.323 1.00 91.49  ? 432 PRO A N   1 
ATOM   3112  C CA  . PRO A 1 411 ? 142.054 168.156 159.785 1.00 91.49  ? 432 PRO A CA  1 
ATOM   3113  C C   . PRO A 1 411 ? 142.211 166.745 159.239 1.00 91.49  ? 432 PRO A C   1 
ATOM   3114  O O   . PRO A 1 411 ? 143.346 166.314 159.017 1.00 91.49  ? 432 PRO A O   1 
ATOM   3115  C CB  . PRO A 1 411 ? 142.962 168.367 161.007 1.00 91.49  ? 432 PRO A CB  1 
ATOM   3116  C CG  . PRO A 1 411 ? 142.102 168.014 162.158 1.00 91.49  ? 432 PRO A CG  1 
ATOM   3117  C CD  . PRO A 1 411 ? 140.718 168.476 161.798 1.00 91.49  ? 432 PRO A CD  1 
ATOM   3118  N N   . ASN A 1 412 ? 141.115 166.012 159.023 1.00 95.34  ? 433 ASN A N   1 
ATOM   3119  C CA  . ASN A 1 412 ? 141.179 164.658 158.495 1.00 95.34  ? 433 ASN A CA  1 
ATOM   3120  C C   . ASN A 1 412 ? 140.765 164.540 157.035 1.00 95.34  ? 433 ASN A C   1 
ATOM   3121  O O   . ASN A 1 412 ? 141.194 163.594 156.368 1.00 95.34  ? 433 ASN A O   1 
ATOM   3122  C CB  . ASN A 1 412 ? 140.315 163.712 159.346 1.00 95.34  ? 433 ASN A CB  1 
ATOM   3123  C CG  . ASN A 1 412 ? 138.912 164.252 159.605 1.00 95.34  ? 433 ASN A CG  1 
ATOM   3124  O OD1 . ASN A 1 412 ? 138.173 164.593 158.681 1.00 95.34  ? 433 ASN A OD1 1 
ATOM   3125  N ND2 . ASN A 1 412 ? 138.542 164.328 160.876 1.00 95.34  ? 433 ASN A ND2 1 
ATOM   3126  N N   . ASN A 1 413 ? 139.947 165.462 156.524 1.00 110.08 ? 434 ASN A N   1 
ATOM   3127  C CA  . ASN A 1 413 ? 139.474 165.367 155.149 1.00 110.08 ? 434 ASN A CA  1 
ATOM   3128  C C   . ASN A 1 413 ? 140.283 166.210 154.167 1.00 110.08 ? 434 ASN A C   1 
ATOM   3129  O O   . ASN A 1 413 ? 140.192 165.980 152.956 1.00 110.08 ? 434 ASN A O   1 
ATOM   3130  C CB  . ASN A 1 413 ? 137.966 165.707 155.089 1.00 110.08 ? 434 ASN A CB  1 
ATOM   3131  C CG  . ASN A 1 413 ? 137.613 167.134 155.579 1.00 110.08 ? 434 ASN A CG  1 
ATOM   3132  O OD1 . ASN A 1 413 ? 138.460 168.019 155.670 1.00 110.08 ? 434 ASN A OD1 1 
ATOM   3133  N ND2 . ASN A 1 413 ? 136.337 167.347 155.919 1.00 110.08 ? 434 ASN A ND2 1 
ATOM   3134  N N   . LEU A 1 414 ? 141.061 167.171 154.662 1.00 97.69  ? 435 LEU A N   1 
ATOM   3135  C CA  . LEU A 1 414 ? 141.953 167.948 153.813 1.00 97.69  ? 435 LEU A CA  1 
ATOM   3136  C C   . LEU A 1 414 ? 143.128 167.099 153.343 1.00 97.69  ? 435 LEU A C   1 
ATOM   3137  O O   . LEU A 1 414 ? 143.476 166.084 153.952 1.00 97.69  ? 435 LEU A O   1 
ATOM   3138  C CB  . LEU A 1 414 ? 142.487 169.172 154.561 1.00 97.69  ? 435 LEU A CB  1 
ATOM   3139  C CG  . LEU A 1 414 ? 141.787 170.530 154.444 1.00 97.69  ? 435 LEU A CG  1 
ATOM   3140  C CD1 . LEU A 1 414 ? 140.496 170.573 155.236 1.00 97.69  ? 435 LEU A CD1 1 
ATOM   3141  C CD2 . LEU A 1 414 ? 142.723 171.641 154.893 1.00 97.69  ? 435 LEU A CD2 1 
ATOM   3142  N N   . THR A 1 415 ? 143.742 167.527 152.245 1.00 81.70  ? 436 THR A N   1 
ATOM   3143  C CA  . THR A 1 415 ? 144.973 166.902 151.794 1.00 81.70  ? 436 THR A CA  1 
ATOM   3144  C C   . THR A 1 415 ? 146.143 167.352 152.667 1.00 81.70  ? 436 THR A C   1 
ATOM   3145  O O   . THR A 1 415 ? 146.080 168.365 153.370 1.00 81.70  ? 436 THR A O   1 
ATOM   3146  C CB  . THR A 1 415 ? 145.240 167.230 150.323 1.00 81.70  ? 436 THR A CB  1 
ATOM   3147  O OG1 . THR A 1 415 ? 146.370 166.481 149.859 1.00 81.70  ? 436 THR A OG1 1 
ATOM   3148  C CG2 . THR A 1 415 ? 145.501 168.719 150.132 1.00 81.70  ? 436 THR A CG2 1 
ATOM   3149  N N   . ILE A 1 416 ? 147.217 166.567 152.635 1.00 76.64  ? 437 ILE A N   1 
ATOM   3150  C CA  . ILE A 1 416 ? 148.405 166.818 153.444 1.00 76.64  ? 437 ILE A CA  1 
ATOM   3151  C C   . ILE A 1 416 ? 149.612 166.838 152.517 1.00 76.64  ? 437 ILE A C   1 
ATOM   3152  O O   . ILE A 1 416 ? 149.857 165.869 151.787 1.00 76.64  ? 437 ILE A O   1 
ATOM   3153  C CB  . ILE A 1 416 ? 148.572 165.766 154.552 1.00 76.64  ? 437 ILE A CB  1 
ATOM   3154  C CG1 . ILE A 1 416 ? 147.523 165.976 155.645 1.00 76.64  ? 437 ILE A CG1 1 
ATOM   3155  C CG2 . ILE A 1 416 ? 149.968 165.822 155.157 1.00 76.64  ? 437 ILE A CG2 1 
ATOM   3156  C CD1 . ILE A 1 416 ? 147.048 164.698 156.284 1.00 76.64  ? 437 ILE A CD1 1 
ATOM   3157  N N   . GLU A 1 417 ? 150.360 167.938 152.545 1.00 77.36  ? 438 GLU A N   1 
ATOM   3158  C CA  . GLU A 1 417 ? 151.581 168.086 151.756 1.00 77.36  ? 438 GLU A CA  1 
ATOM   3159  C C   . GLU A 1 417 ? 152.767 167.927 152.701 1.00 77.36  ? 438 GLU A C   1 
ATOM   3160  O O   . GLU A 1 417 ? 153.100 168.842 153.458 1.00 77.36  ? 438 GLU A O   1 
ATOM   3161  C CB  . GLU A 1 417 ? 151.608 169.434 151.045 1.00 77.36  ? 438 GLU A CB  1 
ATOM   3162  C CG  . GLU A 1 417 ? 150.583 169.577 149.934 1.00 77.36  ? 438 GLU A CG  1 
ATOM   3163  C CD  . GLU A 1 417 ? 150.541 170.980 149.362 1.00 77.36  ? 438 GLU A CD  1 
ATOM   3164  O OE1 . GLU A 1 417 ? 151.226 171.868 149.912 1.00 77.36  ? 438 GLU A OE1 1 
ATOM   3165  O OE2 . GLU A 1 417 ? 149.822 171.197 148.364 1.00 77.36  ? 438 GLU A OE2 1 
ATOM   3166  N N   . ILE A 1 418 ? 153.401 166.761 152.656 1.00 66.80  ? 439 ILE A N   1 
ATOM   3167  C CA  . ILE A 1 418 ? 154.566 166.487 153.491 1.00 66.80  ? 439 ILE A CA  1 
ATOM   3168  C C   . ILE A 1 418 ? 155.772 167.199 152.890 1.00 66.80  ? 439 ILE A C   1 
ATOM   3169  O O   . ILE A 1 418 ? 156.080 167.031 151.704 1.00 66.80  ? 439 ILE A O   1 
ATOM   3170  C CB  . ILE A 1 418 ? 154.818 164.972 153.620 1.00 66.80  ? 439 ILE A CB  1 
ATOM   3171  C CG1 . ILE A 1 418 ? 153.671 164.250 154.349 1.00 66.80  ? 439 ILE A CG1 1 
ATOM   3172  C CG2 . ILE A 1 418 ? 156.135 164.695 154.336 1.00 66.80  ? 439 ILE A CG2 1 
ATOM   3173  C CD1 . ILE A 1 418 ? 152.577 163.659 153.457 1.00 66.80  ? 439 ILE A CD1 1 
ATOM   3174  N N   . GLY A 1 419 ? 156.458 167.995 153.707 1.00 70.05  ? 440 GLY A N   1 
ATOM   3175  C CA  . GLY A 1 419 ? 157.600 168.752 153.252 1.00 70.05  ? 440 GLY A CA  1 
ATOM   3176  C C   . GLY A 1 419 ? 158.861 167.917 153.144 1.00 70.05  ? 440 GLY A C   1 
ATOM   3177  O O   . GLY A 1 419 ? 158.837 166.690 153.291 1.00 70.05  ? 440 GLY A O   1 
ATOM   3178  N N   . PRO A 1 420 ? 159.990 168.568 152.876 1.00 72.22  ? 441 PRO A N   1 
ATOM   3179  C CA  . PRO A 1 420 ? 161.251 167.837 152.710 1.00 72.22  ? 441 PRO A CA  1 
ATOM   3180  C C   . PRO A 1 420 ? 161.792 167.364 154.047 1.00 72.22  ? 441 PRO A C   1 
ATOM   3181  O O   . PRO A 1 420 ? 161.572 168.012 155.081 1.00 72.22  ? 441 PRO A O   1 
ATOM   3182  C CB  . PRO A 1 420 ? 162.178 168.880 152.070 1.00 72.22  ? 441 PRO A CB  1 
ATOM   3183  C CG  . PRO A 1 420 ? 161.657 170.184 152.560 1.00 72.22  ? 441 PRO A CG  1 
ATOM   3184  C CD  . PRO A 1 420 ? 160.166 170.022 152.705 1.00 72.22  ? 441 PRO A CD  1 
ATOM   3185  N N   . PRO A 1 421 ? 162.502 166.228 154.073 1.00 79.70  ? 442 PRO A N   1 
ATOM   3186  C CA  . PRO A 1 421 ? 163.115 165.758 155.324 1.00 79.70  ? 442 PRO A CA  1 
ATOM   3187  C C   . PRO A 1 421 ? 164.355 166.568 155.672 1.00 79.70  ? 442 PRO A C   1 
ATOM   3188  O O   . PRO A 1 421 ? 165.387 166.481 154.999 1.00 79.70  ? 442 PRO A O   1 
ATOM   3189  C CB  . PRO A 1 421 ? 163.452 164.290 155.017 1.00 79.70  ? 442 PRO A CB  1 
ATOM   3190  C CG  . PRO A 1 421 ? 163.524 164.194 153.541 1.00 79.70  ? 442 PRO A CG  1 
ATOM   3191  C CD  . PRO A 1 421 ? 162.660 165.269 152.965 1.00 79.70  ? 442 PRO A CD  1 
ATOM   3192  N N   . VAL A 1 422 ? 164.253 167.365 156.734 1.00 94.74  ? 443 VAL A N   1 
ATOM   3193  C CA  . VAL A 1 422 ? 165.364 168.191 157.203 1.00 94.74  ? 443 VAL A CA  1 
ATOM   3194  C C   . VAL A 1 422 ? 166.277 167.292 158.031 1.00 94.74  ? 443 VAL A C   1 
ATOM   3195  O O   . VAL A 1 422 ? 165.954 166.937 159.166 1.00 94.74  ? 443 VAL A O   1 
ATOM   3196  C CB  . VAL A 1 422 ? 164.878 169.399 158.006 1.00 94.74  ? 443 VAL A CB  1 
ATOM   3197  C CG1 . VAL A 1 422 ? 166.059 170.223 158.495 1.00 94.74  ? 443 VAL A CG1 1 
ATOM   3198  C CG2 . VAL A 1 422 ? 163.946 170.251 157.162 1.00 94.74  ? 443 VAL A CG2 1 
ATOM   3199  N N   . TYR A 1 423 ? 167.423 166.922 157.465 1.00 114.09 ? 444 TYR A N   1 
ATOM   3200  C CA  . TYR A 1 423 ? 168.368 166.046 158.152 1.00 114.09 ? 444 TYR A CA  1 
ATOM   3201  C C   . TYR A 1 423 ? 169.747 166.325 157.570 1.00 114.09 ? 444 TYR A C   1 
ATOM   3202  O O   . TYR A 1 423 ? 170.045 165.897 156.451 1.00 114.09 ? 444 TYR A O   1 
ATOM   3203  C CB  . TYR A 1 423 ? 167.970 164.581 157.986 1.00 114.09 ? 444 TYR A CB  1 
ATOM   3204  C CG  . TYR A 1 423 ? 168.792 163.613 158.800 1.00 114.09 ? 444 TYR A CG  1 
ATOM   3205  C CD1 . TYR A 1 423 ? 168.598 163.499 160.173 1.00 114.09 ? 444 TYR A CD1 1 
ATOM   3206  C CD2 . TYR A 1 423 ? 169.741 162.796 158.199 1.00 114.09 ? 444 TYR A CD2 1 
ATOM   3207  C CE1 . TYR A 1 423 ? 169.339 162.611 160.929 1.00 114.09 ? 444 TYR A CE1 1 
ATOM   3208  C CE2 . TYR A 1 423 ? 170.485 161.901 158.948 1.00 114.09 ? 444 TYR A CE2 1 
ATOM   3209  C CZ  . TYR A 1 423 ? 170.280 161.815 160.311 1.00 114.09 ? 444 TYR A CZ  1 
ATOM   3210  O OH  . TYR A 1 423 ? 171.019 160.929 161.058 1.00 114.09 ? 444 TYR A OH  1 
ATOM   3211  N N   . THR A 1 424 ? 170.580 167.037 158.324 1.00 115.42 ? 445 THR A N   1 
ATOM   3212  C CA  . THR A 1 424 ? 171.840 167.573 157.827 1.00 115.42 ? 445 THR A CA  1 
ATOM   3213  C C   . THR A 1 424 ? 173.018 166.881 158.501 1.00 115.42 ? 445 THR A C   1 
ATOM   3214  O O   . THR A 1 424 ? 173.016 166.674 159.719 1.00 115.42 ? 445 THR A O   1 
ATOM   3215  C CB  . THR A 1 424 ? 171.912 169.085 158.067 1.00 115.42 ? 445 THR A CB  1 
ATOM   3216  O OG1 . THR A 1 424 ? 170.662 169.685 157.703 1.00 115.42 ? 445 THR A OG1 1 
ATOM   3217  C CG2 . THR A 1 424 ? 173.017 169.713 157.236 1.00 115.42 ? 445 THR A CG2 1 
ATOM   3218  N N   . GLU A 1 425 ? 174.026 166.528 157.700 1.00 106.42 ? 446 GLU A N   1 
ATOM   3219  C CA  . GLU A 1 425 ? 175.220 165.838 158.162 1.00 106.42 ? 446 GLU A CA  1 
ATOM   3220  C C   . GLU A 1 425 ? 176.430 166.462 157.473 1.00 106.42 ? 446 GLU A C   1 
ATOM   3221  O O   . GLU A 1 425 ? 176.354 166.787 156.278 1.00 106.42 ? 446 GLU A O   1 
ATOM   3222  C CB  . GLU A 1 425 ? 175.120 164.337 157.852 1.00 106.42 ? 446 GLU A CB  1 
ATOM   3223  C CG  . GLU A 1 425 ? 176.101 163.447 158.590 1.00 106.42 ? 446 GLU A CG  1 
ATOM   3224  C CD  . GLU A 1 425 ? 177.396 163.278 157.839 1.00 106.42 ? 446 GLU A CD  1 
ATOM   3225  O OE1 . GLU A 1 425 ? 177.333 163.013 156.621 1.00 106.42 ? 446 GLU A OE1 1 
ATOM   3226  O OE2 . GLU A 1 425 ? 178.468 163.428 158.460 1.00 106.42 ? 446 GLU A OE2 1 
ATOM   3227  N N   . PRO A 1 426 ? 177.541 166.669 158.202 1.00 102.55 ? 447 PRO A N   1 
ATOM   3228  C CA  . PRO A 1 426 ? 178.691 167.392 157.614 1.00 102.55 ? 447 PRO A CA  1 
ATOM   3229  C C   . PRO A 1 426 ? 179.385 166.691 156.452 1.00 102.55 ? 447 PRO A C   1 
ATOM   3230  O O   . PRO A 1 426 ? 179.825 167.367 155.512 1.00 102.55 ? 447 PRO A O   1 
ATOM   3231  C CB  . PRO A 1 426 ? 179.636 167.551 158.813 1.00 102.55 ? 447 PRO A CB  1 
ATOM   3232  C CG  . PRO A 1 426 ? 178.730 167.580 159.986 1.00 102.55 ? 447 PRO A CG  1 
ATOM   3233  C CD  . PRO A 1 426 ? 177.658 166.577 159.669 1.00 102.55 ? 447 PRO A CD  1 
ATOM   3234  N N   . VAL A 1 427 ? 179.507 165.362 156.488 1.00 100.31 ? 448 VAL A N   1 
ATOM   3235  C CA  . VAL A 1 427 ? 180.181 164.650 155.404 1.00 100.31 ? 448 VAL A CA  1 
ATOM   3236  C C   . VAL A 1 427 ? 179.324 164.671 154.140 1.00 100.31 ? 448 VAL A C   1 
ATOM   3237  O O   . VAL A 1 427 ? 179.840 164.838 153.027 1.00 100.31 ? 448 VAL A O   1 
ATOM   3238  C CB  . VAL A 1 427 ? 180.539 163.218 155.856 1.00 100.31 ? 448 VAL A CB  1 
ATOM   3239  C CG1 . VAL A 1 427 ? 181.050 162.361 154.702 1.00 100.31 ? 448 VAL A CG1 1 
ATOM   3240  C CG2 . VAL A 1 427 ? 181.560 163.262 156.984 1.00 100.31 ? 448 VAL A CG2 1 
ATOM   3241  N N   . ASP A 1 428 ? 178.000 164.549 154.295 1.00 105.97 ? 449 ASP A N   1 
ATOM   3242  C CA  . ASP A 1 428 ? 177.094 164.607 153.148 1.00 105.97 ? 449 ASP A CA  1 
ATOM   3243  C C   . ASP A 1 428 ? 177.071 165.992 152.507 1.00 105.97 ? 449 ASP A C   1 
ATOM   3244  O O   . ASP A 1 428 ? 177.067 166.109 151.271 1.00 105.97 ? 449 ASP A O   1 
ATOM   3245  C CB  . ASP A 1 428 ? 175.685 164.197 153.575 1.00 105.97 ? 449 ASP A CB  1 
ATOM   3246  C CG  . ASP A 1 428 ? 174.710 164.174 152.415 1.00 105.97 ? 449 ASP A CG  1 
ATOM   3247  O OD1 . ASP A 1 428 ? 174.772 163.228 151.602 1.00 105.97 ? 449 ASP A OD1 1 
ATOM   3248  O OD2 . ASP A 1 428 ? 173.883 165.105 152.316 1.00 105.97 ? 449 ASP A OD2 1 
ATOM   3249  N N   . ILE A 1 429 ? 177.063 167.054 153.322 1.00 102.09 ? 450 ILE A N   1 
ATOM   3250  C CA  . ILE A 1 429 ? 177.076 168.391 152.738 1.00 102.09 ? 450 ILE A CA  1 
ATOM   3251  C C   . ILE A 1 429 ? 178.447 168.704 152.152 1.00 102.09 ? 450 ILE A C   1 
ATOM   3252  O O   . ILE A 1 429 ? 178.544 169.431 151.160 1.00 102.09 ? 450 ILE A O   1 
ATOM   3253  C CB  . ILE A 1 429 ? 176.604 169.473 153.734 1.00 102.09 ? 450 ILE A CB  1 
ATOM   3254  C CG1 . ILE A 1 429 ? 177.561 169.645 154.911 1.00 102.09 ? 450 ILE A CG1 1 
ATOM   3255  C CG2 . ILE A 1 429 ? 175.198 169.166 154.226 1.00 102.09 ? 450 ILE A CG2 1 
ATOM   3256  C CD1 . ILE A 1 429 ? 177.266 170.859 155.765 1.00 102.09 ? 450 ILE A CD1 1 
ATOM   3257  N N   . THR A 1 430 ? 179.516 168.111 152.694 1.00 100.82 ? 451 THR A N   1 
ATOM   3258  C CA  . THR A 1 430 ? 180.834 168.261 152.082 1.00 100.82 ? 451 THR A CA  1 
ATOM   3259  C C   . THR A 1 430 ? 180.910 167.519 150.748 1.00 100.82 ? 451 THR A C   1 
ATOM   3260  O O   . THR A 1 430 ? 181.539 167.999 149.798 1.00 100.82 ? 451 THR A O   1 
ATOM   3261  C CB  . THR A 1 430 ? 181.906 167.767 153.054 1.00 100.82 ? 451 THR A CB  1 
ATOM   3262  O OG1 . THR A 1 430 ? 181.780 168.471 154.295 1.00 100.82 ? 451 THR A OG1 1 
ATOM   3263  C CG2 . THR A 1 430 ? 183.313 168.007 152.512 1.00 100.82 ? 451 THR A CG2 1 
ATOM   3264  N N   . ASN A 1 431 ? 180.238 166.369 150.644 1.00 102.41 ? 452 ASN A N   1 
ATOM   3265  C CA  . ASN A 1 431 ? 180.238 165.610 149.394 1.00 102.41 ? 452 ASN A CA  1 
ATOM   3266  C C   . ASN A 1 431 ? 179.434 166.316 148.307 1.00 102.41 ? 452 ASN A C   1 
ATOM   3267  O O   . ASN A 1 431 ? 179.866 166.380 147.149 1.00 102.41 ? 452 ASN A O   1 
ATOM   3268  C CB  . ASN A 1 431 ? 179.692 164.203 149.634 1.00 102.41 ? 452 ASN A CB  1 
ATOM   3269  C CG  . ASN A 1 431 ? 179.956 163.271 148.468 1.00 102.41 ? 452 ASN A CG  1 
ATOM   3270  O OD1 . ASN A 1 431 ? 179.162 163.189 147.531 1.00 102.41 ? 452 ASN A OD1 1 
ATOM   3271  N ND2 . ASN A 1 431 ? 181.078 162.561 148.520 1.00 102.41 ? 452 ASN A ND2 1 
ATOM   3272  N N   . GLN A 1 432 ? 178.271 166.871 148.654 1.00 105.52 ? 453 GLN A N   1 
ATOM   3273  C CA  . GLN A 1 432 ? 177.547 167.649 147.652 1.00 105.52 ? 453 GLN A CA  1 
ATOM   3274  C C   . GLN A 1 432 ? 178.215 168.994 147.373 1.00 105.52 ? 453 GLN A C   1 
ATOM   3275  O O   . GLN A 1 432 ? 178.077 169.521 146.265 1.00 105.52 ? 453 GLN A O   1 
ATOM   3276  C CB  . GLN A 1 432 ? 176.087 167.841 148.067 1.00 105.52 ? 453 GLN A CB  1 
ATOM   3277  C CG  . GLN A 1 432 ? 175.918 168.662 149.301 1.00 105.52 ? 453 GLN A CG  1 
ATOM   3278  C CD  . GLN A 1 432 ? 174.490 168.781 149.755 1.00 105.52 ? 453 GLN A CD  1 
ATOM   3279  O OE1 . GLN A 1 432 ? 174.194 169.375 150.792 1.00 105.52 ? 453 GLN A OE1 1 
ATOM   3280  N NE2 . GLN A 1 432 ? 173.584 168.243 148.954 1.00 105.52 ? 453 GLN A NE2 1 
ATOM   3281  N N   . LEU A 1 433 ? 178.990 169.534 148.320 1.00 106.80 ? 454 LEU A N   1 
ATOM   3282  C CA  . LEU A 1 433 ? 179.824 170.685 147.999 1.00 106.80 ? 454 LEU A CA  1 
ATOM   3283  C C   . LEU A 1 433 ? 180.951 170.312 147.049 1.00 106.80 ? 454 LEU A C   1 
ATOM   3284  O O   . LEU A 1 433 ? 181.298 171.109 146.183 1.00 106.80 ? 454 LEU A O   1 
ATOM   3285  C CB  . LEU A 1 433 ? 180.376 171.325 149.273 1.00 106.80 ? 454 LEU A CB  1 
ATOM   3286  C CG  . LEU A 1 433 ? 179.653 172.579 149.784 1.00 106.80 ? 454 LEU A CG  1 
ATOM   3287  C CD1 . LEU A 1 433 ? 178.139 172.415 149.862 1.00 106.80 ? 454 LEU A CD1 1 
ATOM   3288  C CD2 . LEU A 1 433 ? 180.215 172.996 151.137 1.00 106.80 ? 454 LEU A CD2 1 
ATOM   3289  N N   . GLY A 1 434 ? 181.513 169.109 147.176 1.00 105.13 ? 455 GLY A N   1 
ATOM   3290  C CA  . GLY A 1 434 ? 182.460 168.628 146.182 1.00 105.13 ? 455 GLY A CA  1 
ATOM   3291  C C   . GLY A 1 434 ? 181.816 168.389 144.830 1.00 105.13 ? 455 GLY A C   1 
ATOM   3292  O O   . GLY A 1 434 ? 182.473 168.515 143.789 1.00 105.13 ? 455 GLY A O   1 
ATOM   3293  N N   . ASN A 1 435 ? 180.526 168.044 144.828 1.00 107.35 ? 456 ASN A N   1 
ATOM   3294  C CA  . ASN A 1 435 ? 179.766 168.046 143.582 1.00 107.35 ? 456 ASN A CA  1 
ATOM   3295  C C   . ASN A 1 435 ? 179.665 169.456 143.002 1.00 107.35 ? 456 ASN A C   1 
ATOM   3296  O O   . ASN A 1 435 ? 179.737 169.630 141.784 1.00 107.35 ? 456 ASN A O   1 
ATOM   3297  C CB  . ASN A 1 435 ? 178.377 167.444 143.794 1.00 107.35 ? 456 ASN A CB  1 
ATOM   3298  C CG  . ASN A 1 435 ? 177.655 167.171 142.489 1.00 107.35 ? 456 ASN A CG  1 
ATOM   3299  O OD1 . ASN A 1 435 ? 177.010 168.056 141.926 1.00 107.35 ? 456 ASN A OD1 1 
ATOM   3300  N ND2 . ASN A 1 435 ? 177.753 165.938 142.004 1.00 107.35 ? 456 ASN A ND2 1 
ATOM   3301  N N   . ILE A 1 436 ? 179.530 170.475 143.859 1.00 111.20 ? 457 ILE A N   1 
ATOM   3302  C CA  . ILE A 1 436 ? 179.565 171.863 143.378 1.00 111.20 ? 457 ILE A CA  1 
ATOM   3303  C C   . ILE A 1 436 ? 180.961 172.238 142.863 1.00 111.20 ? 457 ILE A C   1 
ATOM   3304  O O   . ILE A 1 436 ? 181.088 172.968 141.875 1.00 111.20 ? 457 ILE A O   1 
ATOM   3305  C CB  . ILE A 1 436 ? 179.068 172.835 144.472 1.00 111.20 ? 457 ILE A CB  1 
ATOM   3306  C CG1 . ILE A 1 436 ? 177.678 172.435 144.962 1.00 111.20 ? 457 ILE A CG1 1 
ATOM   3307  C CG2 . ILE A 1 436 ? 179.019 174.280 143.982 1.00 111.20 ? 457 ILE A CG2 1 
ATOM   3308  C CD1 . ILE A 1 436 ? 176.617 172.454 143.883 1.00 111.20 ? 457 ILE A CD1 1 
ATOM   3309  N N   . ASN A 1 437 ? 182.017 171.762 143.540 1.00 118.79 ? 458 ASN A N   1 
ATOM   3310  C CA  . ASN A 1 437 ? 183.415 171.910 143.108 1.00 118.79 ? 458 ASN A CA  1 
ATOM   3311  C C   . ASN A 1 437 ? 183.638 171.392 141.684 1.00 118.79 ? 458 ASN A C   1 
ATOM   3312  O O   . ASN A 1 437 ? 184.066 172.143 140.788 1.00 118.79 ? 458 ASN A O   1 
ATOM   3313  C CB  . ASN A 1 437 ? 184.316 171.202 144.141 1.00 118.79 ? 458 ASN A CB  1 
ATOM   3314  C CG  . ASN A 1 437 ? 184.647 172.093 145.352 1.00 118.79 ? 458 ASN A CG  1 
ATOM   3315  O OD1 . ASN A 1 437 ? 183.786 172.326 146.183 1.00 118.79 ? 458 ASN A OD1 1 
ATOM   3316  N ND2 . ASN A 1 437 ? 185.912 172.484 145.534 1.00 118.79 ? 458 ASN A ND2 1 
ATOM   3317  N N   . GLU A 1 438 ? 183.268 170.128 141.440 1.00 112.04 ? 459 GLU A N   1 
ATOM   3318  C CA  . GLU A 1 438 ? 183.389 169.580 140.089 1.00 112.04 ? 459 GLU A CA  1 
ATOM   3319  C C   . GLU A 1 438 ? 182.396 170.222 139.125 1.00 112.04 ? 459 GLU A C   1 
ATOM   3320  O O   . GLU A 1 438 ? 182.686 170.328 137.928 1.00 112.04 ? 459 GLU A O   1 
ATOM   3321  C CB  . GLU A 1 438 ? 183.249 168.052 140.106 1.00 112.04 ? 459 GLU A CB  1 
ATOM   3322  C CG  . GLU A 1 438 ? 181.941 167.487 140.641 1.00 112.04 ? 459 GLU A CG  1 
ATOM   3323  C CD  . GLU A 1 438 ? 180.872 167.316 139.578 1.00 112.04 ? 459 GLU A CD  1 
ATOM   3324  O OE1 . GLU A 1 438 ? 181.222 167.278 138.381 1.00 112.04 ? 459 GLU A OE1 1 
ATOM   3325  O OE2 . GLU A 1 438 ? 179.681 167.222 139.942 1.00 112.04 ? 459 GLU A OE2 1 
ATOM   3326  N N   . THR A 1 439 ? 181.262 170.716 139.636 1.00 107.94 ? 460 THR A N   1 
ATOM   3327  C CA  . THR A 1 439 ? 180.279 171.368 138.781 1.00 107.94 ? 460 THR A CA  1 
ATOM   3328  C C   . THR A 1 439 ? 180.787 172.702 138.252 1.00 107.94 ? 460 THR A C   1 
ATOM   3329  O O   . THR A 1 439 ? 180.676 172.966 137.049 1.00 107.94 ? 460 THR A O   1 
ATOM   3330  C CB  . THR A 1 439 ? 178.966 171.560 139.540 1.00 107.94 ? 460 THR A CB  1 
ATOM   3331  O OG1 . THR A 1 439 ? 178.477 170.286 139.975 1.00 107.94 ? 460 THR A OG1 1 
ATOM   3332  C CG2 . THR A 1 439 ? 177.929 172.208 138.643 1.00 107.94 ? 460 THR A CG2 1 
ATOM   3333  N N   . LEU A 1 440 ? 181.368 173.553 139.112 1.00 108.24 ? 461 LEU A N   1 
ATOM   3334  C CA  . LEU A 1 440 ? 181.845 174.814 138.560 1.00 108.24 ? 461 LEU A CA  1 
ATOM   3335  C C   . LEU A 1 440 ? 183.128 174.620 137.776 1.00 108.24 ? 461 LEU A C   1 
ATOM   3336  O O   . LEU A 1 440 ? 183.394 175.411 136.872 1.00 108.24 ? 461 LEU A O   1 
ATOM   3337  C CB  . LEU A 1 440 ? 182.114 175.940 139.574 1.00 108.24 ? 461 LEU A CB  1 
ATOM   3338  C CG  . LEU A 1 440 ? 183.317 176.136 140.511 1.00 108.24 ? 461 LEU A CG  1 
ATOM   3339  C CD1 . LEU A 1 440 ? 183.315 177.582 140.979 1.00 108.24 ? 461 LEU A CD1 1 
ATOM   3340  C CD2 . LEU A 1 440 ? 183.347 175.275 141.711 1.00 108.24 ? 461 LEU A CD2 1 
ATOM   3341  N N   . SER A 1 441 ? 183.909 173.573 138.062 1.00 115.36 ? 462 SER A N   1 
ATOM   3342  C CA  . SER A 1 441 ? 185.078 173.356 137.217 1.00 115.36 ? 462 SER A CA  1 
ATOM   3343  C C   . SER A 1 441 ? 184.719 172.788 135.844 1.00 115.36 ? 462 SER A C   1 
ATOM   3344  O O   . SER A 1 441 ? 185.181 173.316 134.829 1.00 115.36 ? 462 SER A O   1 
ATOM   3345  C CB  . SER A 1 441 ? 186.078 172.448 137.940 1.00 115.36 ? 462 SER A CB  1 
ATOM   3346  O OG  . SER A 1 441 ? 186.341 172.927 139.247 1.00 115.36 ? 462 SER A OG  1 
ATOM   3347  N N   . LYS A 1 442 ? 183.586 172.031 135.732 1.00 109.04 ? 463 LYS A N   1 
ATOM   3348  C CA  . LYS A 1 442 ? 182.915 171.749 134.424 1.00 109.04 ? 463 LYS A CA  1 
ATOM   3349  C C   . LYS A 1 442 ? 182.356 172.997 133.744 1.00 109.04 ? 463 LYS A C   1 
ATOM   3350  O O   . LYS A 1 442 ? 182.546 173.170 132.533 1.00 109.04 ? 463 LYS A O   1 
ATOM   3351  C CB  . LYS A 1 442 ? 181.803 170.712 134.604 1.00 109.04 ? 463 LYS A CB  1 
ATOM   3352  C CG  . LYS A 1 442 ? 182.312 169.292 134.804 1.00 109.04 ? 463 LYS A CG  1 
ATOM   3353  C CD  . LYS A 1 442 ? 181.167 168.305 134.953 1.00 109.04 ? 463 LYS A CD  1 
ATOM   3354  C CE  . LYS A 1 442 ? 181.682 166.880 135.083 1.00 109.04 ? 463 LYS A CE  1 
ATOM   3355  N NZ  . LYS A 1 442 ? 180.570 165.903 135.244 1.00 109.04 ? 463 LYS A NZ  1 
ATOM   3356  N N   . THR A 1 443 ? 181.647 173.862 134.483 1.00 107.38 ? 464 THR A N   1 
ATOM   3357  C CA  . THR A 1 443 ? 181.022 175.012 133.827 1.00 107.38 ? 464 THR A CA  1 
ATOM   3358  C C   . THR A 1 443 ? 182.062 176.028 133.382 1.00 107.38 ? 464 THR A C   1 
ATOM   3359  O O   . THR A 1 443 ? 181.923 176.615 132.311 1.00 107.38 ? 464 THR A O   1 
ATOM   3360  C CB  . THR A 1 443 ? 179.980 175.701 134.715 1.00 107.38 ? 464 THR A CB  1 
ATOM   3361  O OG1 . THR A 1 443 ? 180.593 176.201 135.905 1.00 107.38 ? 464 THR A OG1 1 
ATOM   3362  C CG2 . THR A 1 443 ? 178.828 174.768 135.055 1.00 107.38 ? 464 THR A CG2 1 
ATOM   3363  N N   . LEU A 1 444 ? 183.127 176.224 134.161 1.00 111.71 ? 465 LEU A N   1 
ATOM   3364  C CA  . LEU A 1 444 ? 184.211 177.088 133.717 1.00 111.71 ? 465 LEU A CA  1 
ATOM   3365  C C   . LEU A 1 444 ? 184.991 176.505 132.546 1.00 111.71 ? 465 LEU A C   1 
ATOM   3366  O O   . LEU A 1 444 ? 185.404 177.275 131.675 1.00 111.71 ? 465 LEU A O   1 
ATOM   3367  C CB  . LEU A 1 444 ? 185.164 177.409 134.871 1.00 111.71 ? 465 LEU A CB  1 
ATOM   3368  C CG  . LEU A 1 444 ? 184.606 178.328 135.961 1.00 111.71 ? 465 LEU A CG  1 
ATOM   3369  C CD1 . LEU A 1 444 ? 185.586 178.452 137.116 1.00 111.71 ? 465 LEU A CD1 1 
ATOM   3370  C CD2 . LEU A 1 444 ? 184.269 179.697 135.387 1.00 111.71 ? 465 LEU A CD2 1 
ATOM   3371  N N   . ASP A 1 445 ? 185.170 175.177 132.480 1.00 116.89 ? 466 ASP A N   1 
ATOM   3372  C CA  . ASP A 1 445 ? 185.797 174.581 131.298 1.00 116.89 ? 466 ASP A CA  1 
ATOM   3373  C C   . ASP A 1 445 ? 184.935 174.769 130.051 1.00 116.89 ? 466 ASP A C   1 
ATOM   3374  O O   . ASP A 1 445 ? 185.442 175.134 128.979 1.00 116.89 ? 466 ASP A O   1 
ATOM   3375  C CB  . ASP A 1 445 ? 186.074 173.097 131.540 1.00 116.89 ? 466 ASP A CB  1 
ATOM   3376  C CG  . ASP A 1 445 ? 187.224 172.867 132.498 1.00 116.89 ? 466 ASP A CG  1 
ATOM   3377  O OD1 . ASP A 1 445 ? 187.982 173.826 132.759 1.00 116.89 ? 466 ASP A OD1 1 
ATOM   3378  O OD2 . ASP A 1 445 ? 187.371 171.729 132.991 1.00 116.89 ? 466 ASP A OD2 1 
ATOM   3379  N N   . LEU A 1 446 ? 183.622 174.563 130.183 1.00 108.22 ? 467 LEU A N   1 
ATOM   3380  C CA  . LEU A 1 446 ? 182.731 174.742 129.041 1.00 108.22 ? 467 LEU A CA  1 
ATOM   3381  C C   . LEU A 1 446 ? 182.568 176.211 128.666 1.00 108.22 ? 467 LEU A C   1 
ATOM   3382  O O   . LEU A 1 446 ? 182.362 176.524 127.491 1.00 108.22 ? 467 LEU A O   1 
ATOM   3383  C CB  . LEU A 1 446 ? 181.375 174.103 129.330 1.00 108.22 ? 467 LEU A CB  1 
ATOM   3384  C CG  . LEU A 1 446 ? 181.439 172.580 129.447 1.00 108.22 ? 467 LEU A CG  1 
ATOM   3385  C CD1 . LEU A 1 446 ? 180.131 172.032 129.968 1.00 108.22 ? 467 LEU A CD1 1 
ATOM   3386  C CD2 . LEU A 1 446 ? 181.789 171.955 128.106 1.00 108.22 ? 467 LEU A CD2 1 
ATOM   3387  N N   . ILE A 1 447 ? 182.687 177.124 129.631 1.00 107.37 ? 468 ILE A N   1 
ATOM   3388  C CA  . ILE A 1 447 ? 182.615 178.549 129.322 1.00 107.37 ? 468 ILE A CA  1 
ATOM   3389  C C   . ILE A 1 447 ? 183.909 179.034 128.671 1.00 107.37 ? 468 ILE A C   1 
ATOM   3390  O O   . ILE A 1 447 ? 183.873 179.882 127.775 1.00 107.37 ? 468 ILE A O   1 
ATOM   3391  C CB  . ILE A 1 447 ? 182.208 179.340 130.586 1.00 107.37 ? 468 ILE A CB  1 
ATOM   3392  C CG1 . ILE A 1 447 ? 180.702 179.169 130.808 1.00 107.37 ? 468 ILE A CG1 1 
ATOM   3393  C CG2 . ILE A 1 447 ? 182.561 180.827 130.527 1.00 107.37 ? 468 ILE A CG2 1 
ATOM   3394  C CD1 . ILE A 1 447 ? 180.221 179.633 132.139 1.00 107.37 ? 468 ILE A CD1 1 
ATOM   3395  N N   . LYS A 1 448 ? 185.061 178.464 129.050 1.00 110.27 ? 469 LYS A N   1 
ATOM   3396  C CA  . LYS A 1 448 ? 186.296 178.744 128.310 1.00 110.27 ? 469 LYS A CA  1 
ATOM   3397  C C   . LYS A 1 448 ? 186.224 178.223 126.876 1.00 110.27 ? 469 LYS A C   1 
ATOM   3398  O O   . LYS A 1 448 ? 186.651 178.914 125.936 1.00 110.27 ? 469 LYS A O   1 
ATOM   3399  C CB  . LYS A 1 448 ? 187.503 178.144 129.030 1.00 110.27 ? 469 LYS A CB  1 
ATOM   3400  C CG  . LYS A 1 448 ? 187.895 178.850 130.317 1.00 110.27 ? 469 LYS A CG  1 
ATOM   3401  C CD  . LYS A 1 448 ? 189.073 178.155 130.979 1.00 110.27 ? 469 LYS A CD  1 
ATOM   3402  C CE  . LYS A 1 448 ? 189.487 178.858 132.259 1.00 110.27 ? 469 LYS A CE  1 
ATOM   3403  N NZ  . LYS A 1 448 ? 190.632 178.170 132.916 1.00 110.27 ? 469 LYS A NZ  1 
ATOM   3404  N N   . GLN A 1 449 ? 185.662 177.020 126.691 1.00 109.61 ? 470 GLN A N   1 
ATOM   3405  C CA  . GLN A 1 449 ? 185.449 176.483 125.346 1.00 109.61 ? 470 GLN A CA  1 
ATOM   3406  C C   . GLN A 1 449 ? 184.485 177.348 124.538 1.00 109.61 ? 470 GLN A C   1 
ATOM   3407  O O   . GLN A 1 449 ? 184.753 177.666 123.371 1.00 109.61 ? 470 GLN A O   1 
ATOM   3408  C CB  . GLN A 1 449 ? 184.933 175.046 125.434 1.00 109.61 ? 470 GLN A CB  1 
ATOM   3409  C CG  . GLN A 1 449 ? 184.714 174.378 124.086 1.00 109.61 ? 470 GLN A CG  1 
ATOM   3410  C CD  . GLN A 1 449 ? 185.990 174.257 123.278 1.00 109.61 ? 470 GLN A CD  1 
ATOM   3411  O OE1 . GLN A 1 449 ? 186.206 175.001 122.321 1.00 109.61 ? 470 GLN A OE1 1 
ATOM   3412  N NE2 . GLN A 1 449 ? 186.844 173.314 123.659 1.00 109.61 ? 470 GLN A NE2 1 
ATOM   3413  N N   . SER A 1 450 ? 183.385 177.783 125.156 1.00 104.73 ? 471 SER A N   1 
ATOM   3414  C CA  . SER A 1 450 ? 182.427 178.623 124.456 1.00 104.73 ? 471 SER A CA  1 
ATOM   3415  C C   . SER A 1 450 ? 182.951 180.029 124.214 1.00 104.73 ? 471 SER A C   1 
ATOM   3416  O O   . SER A 1 450 ? 182.547 180.646 123.236 1.00 104.73 ? 471 SER A O   1 
ATOM   3417  C CB  . SER A 1 450 ? 181.104 178.696 125.223 1.00 104.73 ? 471 SER A CB  1 
ATOM   3418  O OG  . SER A 1 450 ? 181.256 179.383 126.448 1.00 104.73 ? 471 SER A OG  1 
ATOM   3419  N N   . ASN A 1 451 ? 183.867 180.534 125.046 1.00 106.69 ? 472 ASN A N   1 
ATOM   3420  C CA  . ASN A 1 451 ? 184.477 181.836 124.780 1.00 106.69 ? 472 ASN A CA  1 
ATOM   3421  C C   . ASN A 1 451 ? 185.466 181.753 123.626 1.00 106.69 ? 472 ASN A C   1 
ATOM   3422  O O   . ASN A 1 451 ? 185.578 182.696 122.829 1.00 106.69 ? 472 ASN A O   1 
ATOM   3423  C CB  . ASN A 1 451 ? 185.171 182.369 126.035 1.00 106.69 ? 472 ASN A CB  1 
ATOM   3424  C CG  . ASN A 1 451 ? 184.194 182.883 127.072 1.00 106.69 ? 472 ASN A CG  1 
ATOM   3425  O OD1 . ASN A 1 451 ? 183.061 183.240 126.752 1.00 106.69 ? 472 ASN A OD1 1 
ATOM   3426  N ND2 . ASN A 1 451 ? 184.629 182.921 128.326 1.00 106.69 ? 472 ASN A ND2 1 
ATOM   3427  N N   . SER A 1 452 ? 186.199 180.636 123.531 1.00 107.02 ? 473 SER A N   1 
ATOM   3428  C CA  . SER A 1 452 ? 187.029 180.390 122.353 1.00 107.02 ? 473 SER A CA  1 
ATOM   3429  C C   . SER A 1 452 ? 186.175 180.286 121.094 1.00 107.02 ? 473 SER A C   1 
ATOM   3430  O O   . SER A 1 452 ? 186.580 180.740 120.017 1.00 107.02 ? 473 SER A O   1 
ATOM   3431  C CB  . SER A 1 452 ? 187.855 179.120 122.549 1.00 107.02 ? 473 SER A CB  1 
ATOM   3432  O OG  . SER A 1 452 ? 187.019 177.984 122.685 1.00 107.02 ? 473 SER A OG  1 
ATOM   3433  N N   . ILE A 1 453 ? 184.987 179.691 121.216 1.00 106.50 ? 474 ILE A N   1 
ATOM   3434  C CA  . ILE A 1 453 ? 184.033 179.662 120.109 1.00 106.50 ? 474 ILE A CA  1 
ATOM   3435  C C   . ILE A 1 453 ? 183.466 181.058 119.818 1.00 106.50 ? 474 ILE A C   1 
ATOM   3436  O O   . ILE A 1 453 ? 183.246 181.417 118.652 1.00 106.50 ? 474 ILE A O   1 
ATOM   3437  C CB  . ILE A 1 453 ? 182.969 178.594 120.433 1.00 106.50 ? 474 ILE A CB  1 
ATOM   3438  C CG1 . ILE A 1 453 ? 183.638 177.219 120.324 1.00 106.50 ? 474 ILE A CG1 1 
ATOM   3439  C CG2 . ILE A 1 453 ? 181.742 178.694 119.533 1.00 106.50 ? 474 ILE A CG2 1 
ATOM   3440  C CD1 . ILE A 1 453 ? 182.880 176.079 120.924 1.00 106.50 ? 474 ILE A CD1 1 
ATOM   3441  N N   . LEU A 1 454 ? 183.278 181.887 120.853 1.00 105.19 ? 475 LEU A N   1 
ATOM   3442  C CA  . LEU A 1 454 ? 182.866 183.280 120.673 1.00 105.19 ? 475 LEU A CA  1 
ATOM   3443  C C   . LEU A 1 454 ? 183.957 184.124 120.024 1.00 105.19 ? 475 LEU A C   1 
ATOM   3444  O O   . LEU A 1 454 ? 183.674 185.208 119.503 1.00 105.19 ? 475 LEU A O   1 
ATOM   3445  C CB  . LEU A 1 454 ? 182.478 183.923 122.010 1.00 105.19 ? 475 LEU A CB  1 
ATOM   3446  C CG  . LEU A 1 454 ? 181.215 183.553 122.793 1.00 105.19 ? 475 LEU A CG  1 
ATOM   3447  C CD1 . LEU A 1 454 ? 181.182 184.282 124.131 1.00 105.19 ? 475 LEU A CD1 1 
ATOM   3448  C CD2 . LEU A 1 454 ? 179.965 183.831 121.996 1.00 105.19 ? 475 LEU A CD2 1 
ATOM   3449  N N   . ASP A 1 455 ? 185.207 183.664 120.063 1.00 112.14 ? 476 ASP A N   1 
ATOM   3450  C CA  . ASP A 1 455 ? 186.288 184.437 119.460 1.00 112.14 ? 476 ASP A CA  1 
ATOM   3451  C C   . ASP A 1 455 ? 186.480 184.101 117.982 1.00 112.14 ? 476 ASP A C   1 
ATOM   3452  O O   . ASP A 1 455 ? 186.399 184.983 117.120 1.00 112.14 ? 476 ASP A O   1 
ATOM   3453  C CB  . ASP A 1 455 ? 187.588 184.207 120.233 1.00 112.14 ? 476 ASP A CB  1 
ATOM   3454  C CG  . ASP A 1 455 ? 187.571 184.852 121.603 1.00 112.14 ? 476 ASP A CG  1 
ATOM   3455  O OD1 . ASP A 1 455 ? 186.686 185.698 121.852 1.00 112.14 ? 476 ASP A OD1 1 
ATOM   3456  O OD2 . ASP A 1 455 ? 188.441 184.511 122.431 1.00 112.14 ? 476 ASP A OD2 1 
ATOM   3457  N N   . MET A 1 456 ? 186.735 182.827 117.668 1.00 114.11 ? 477 MET A N   1 
ATOM   3458  C CA  . MET A 1 456 ? 187.309 182.500 116.365 1.00 114.11 ? 477 MET A CA  1 
ATOM   3459  C C   . MET A 1 456 ? 186.336 181.805 115.411 1.00 114.11 ? 477 MET A C   1 
ATOM   3460  O O   . MET A 1 456 ? 186.756 181.357 114.338 1.00 114.11 ? 477 MET A O   1 
ATOM   3461  C CB  . MET A 1 456 ? 188.593 181.682 116.571 1.00 114.11 ? 477 MET A CB  1 
ATOM   3462  C CG  . MET A 1 456 ? 188.473 180.351 117.328 1.00 114.11 ? 477 MET A CG  1 
ATOM   3463  S SD  . MET A 1 456 ? 187.897 178.901 116.426 1.00 114.11 ? 477 MET A SD  1 
ATOM   3464  C CE  . MET A 1 456 ? 189.303 178.574 115.368 1.00 114.11 ? 477 MET A CE  1 
ATOM   3465  N N   . ILE A 1 457 ? 185.053 181.697 115.762 1.00 106.45 ? 478 ILE A N   1 
ATOM   3466  C CA  . ILE A 1 457 ? 184.025 181.200 114.845 1.00 106.45 ? 478 ILE A CA  1 
ATOM   3467  C C   . ILE A 1 457 ? 182.876 182.189 114.673 1.00 106.45 ? 478 ILE A C   1 
ATOM   3468  O O   . ILE A 1 457 ? 182.313 182.288 113.566 1.00 106.45 ? 478 ILE A O   1 
ATOM   3469  C CB  . ILE A 1 457 ? 183.551 179.788 115.268 1.00 106.45 ? 478 ILE A CB  1 
ATOM   3470  C CG1 . ILE A 1 457 ? 184.644 178.786 114.888 1.00 106.45 ? 478 ILE A CG1 1 
ATOM   3471  C CG2 . ILE A 1 457 ? 182.219 179.330 114.658 1.00 106.45 ? 478 ILE A CG2 1 
ATOM   3472  C CD1 . ILE A 1 457 ? 184.472 177.402 115.402 1.00 106.45 ? 478 ILE A CD1 1 
ATOM   3473  N N   . THR A 1 458 ? 182.601 183.025 115.682 1.00 101.45 ? 479 THR A N   1 
ATOM   3474  C CA  . THR A 1 458 ? 181.738 184.184 115.467 1.00 101.45 ? 479 THR A CA  1 
ATOM   3475  C C   . THR A 1 458 ? 182.352 185.193 114.500 1.00 101.45 ? 479 THR A C   1 
ATOM   3476  O O   . THR A 1 458 ? 181.613 185.950 113.861 1.00 101.45 ? 479 THR A O   1 
ATOM   3477  C CB  . THR A 1 458 ? 181.426 184.878 116.792 1.00 101.45 ? 479 THR A CB  1 
ATOM   3478  O OG1 . THR A 1 458 ? 182.648 185.280 117.422 1.00 101.45 ? 479 THR A OG1 1 
ATOM   3479  C CG2 . THR A 1 458 ? 180.652 183.948 117.714 1.00 101.45 ? 479 THR A CG2 1 
ATOM   3480  N N   . GLY A 1 459 ? 183.678 185.218 114.379 1.00 95.46  ? 480 GLY A N   1 
ATOM   3481  C CA  . GLY A 1 459 ? 184.335 185.919 113.295 1.00 95.46  ? 480 GLY A CA  1 
ATOM   3482  C C   . GLY A 1 459 ? 184.877 184.944 112.269 1.00 95.46  ? 480 GLY A C   1 
ATOM   3483  O O   . GLY A 1 459 ? 185.800 185.265 111.515 1.00 95.46  ? 480 GLY A O   1 
ATOM   3484  N N   . GLY A 1 460 ? 184.307 183.742 112.241 1.00 98.69  ? 481 GLY A N   1 
ATOM   3485  C CA  . GLY A 1 460 ? 184.763 182.726 111.305 1.00 98.69  ? 481 GLY A CA  1 
ATOM   3486  C C   . GLY A 1 460 ? 184.185 182.959 109.921 1.00 98.69  ? 481 GLY A C   1 
ATOM   3487  O O   . GLY A 1 460 ? 183.031 183.386 109.781 1.00 98.69  ? 481 GLY A O   1 
ATOM   3488  N N   . LEU A 1 461 ? 184.992 182.673 108.895 1.00 88.79  ? 482 LEU A N   1 
ATOM   3489  C CA  . LEU A 1 461 ? 184.681 182.866 107.468 1.00 88.79  ? 482 LEU A CA  1 
ATOM   3490  C C   . LEU A 1 461 ? 184.243 184.292 107.132 1.00 88.79  ? 482 LEU A C   1 
ATOM   3491  O O   . LEU A 1 461 ? 184.694 185.252 107.757 1.00 88.79  ? 482 LEU A O   1 
ATOM   3492  C CB  . LEU A 1 461 ? 183.610 181.870 106.998 1.00 88.79  ? 482 LEU A CB  1 
ATOM   3493  C CG  . LEU A 1 461 ? 183.989 180.388 107.008 1.00 88.79  ? 482 LEU A CG  1 
ATOM   3494  C CD1 . LEU A 1 461 ? 182.788 179.525 106.652 1.00 88.79  ? 482 LEU A CD1 1 
ATOM   3495  C CD2 . LEU A 1 461 ? 185.145 180.123 106.056 1.00 88.79  ? 482 LEU A CD2 1 
ATOM   3496  N N   . VAL B 1 1   ? 195.843 193.636 159.493 1.00 95.47  ? 22  VAL B N   1 
ATOM   3497  C CA  . VAL B 1 1   ? 194.444 193.986 159.700 1.00 95.47  ? 22  VAL B CA  1 
ATOM   3498  C C   . VAL B 1 1   ? 194.242 195.488 159.436 1.00 95.47  ? 22  VAL B C   1 
ATOM   3499  O O   . VAL B 1 1   ? 195.099 196.315 159.758 1.00 95.47  ? 22  VAL B O   1 
ATOM   3500  C CB  . VAL B 1 1   ? 193.972 193.541 161.126 1.00 95.47  ? 22  VAL B CB  1 
ATOM   3501  C CG1 . VAL B 1 1   ? 194.731 194.264 162.237 1.00 95.47  ? 22  VAL B CG1 1 
ATOM   3502  C CG2 . VAL B 1 1   ? 192.464 193.702 161.295 1.00 95.47  ? 22  VAL B CG2 1 
ATOM   3503  N N   . ASP B 1 2   ? 193.131 195.829 158.783 1.00 95.55  ? 23  ASP B N   1 
ATOM   3504  C CA  . ASP B 1 2   ? 192.782 197.214 158.485 1.00 95.55  ? 23  ASP B CA  1 
ATOM   3505  C C   . ASP B 1 2   ? 191.545 197.579 159.295 1.00 95.55  ? 23  ASP B C   1 
ATOM   3506  O O   . ASP B 1 2   ? 190.465 197.018 159.082 1.00 95.55  ? 23  ASP B O   1 
ATOM   3507  C CB  . ASP B 1 2   ? 192.539 197.406 156.989 1.00 95.55  ? 23  ASP B CB  1 
ATOM   3508  C CG  . ASP B 1 2   ? 192.581 198.865 156.573 1.00 95.55  ? 23  ASP B CG  1 
ATOM   3509  O OD1 . ASP B 1 2   ? 191.623 199.605 156.883 1.00 95.55  ? 23  ASP B OD1 1 
ATOM   3510  O OD2 . ASP B 1 2   ? 193.572 199.271 155.932 1.00 95.55  ? 23  ASP B OD2 1 
ATOM   3511  N N   . PHE B 1 3   ? 191.701 198.524 160.222 1.00 83.80  ? 24  PHE B N   1 
ATOM   3512  C CA  . PHE B 1 3   ? 190.601 198.895 161.100 1.00 83.80  ? 24  PHE B CA  1 
ATOM   3513  C C   . PHE B 1 3   ? 189.650 199.906 160.475 1.00 83.80  ? 24  PHE B C   1 
ATOM   3514  O O   . PHE B 1 3   ? 188.527 200.054 160.965 1.00 83.80  ? 24  PHE B O   1 
ATOM   3515  C CB  . PHE B 1 3   ? 191.146 199.447 162.417 1.00 83.80  ? 24  PHE B CB  1 
ATOM   3516  C CG  . PHE B 1 3   ? 191.913 198.440 163.221 1.00 83.80  ? 24  PHE B CG  1 
ATOM   3517  C CD1 . PHE B 1 3   ? 191.262 197.365 163.808 1.00 83.80  ? 24  PHE B CD1 1 
ATOM   3518  C CD2 . PHE B 1 3   ? 193.284 198.564 163.387 1.00 83.80  ? 24  PHE B CD2 1 
ATOM   3519  C CE1 . PHE B 1 3   ? 191.964 196.431 164.549 1.00 83.80  ? 24  PHE B CE1 1 
ATOM   3520  C CE2 . PHE B 1 3   ? 193.994 197.635 164.128 1.00 83.80  ? 24  PHE B CE2 1 
ATOM   3521  C CZ  . PHE B 1 3   ? 193.332 196.567 164.710 1.00 83.80  ? 24  PHE B CZ  1 
ATOM   3522  N N   . GLU B 1 4   ? 190.061 200.596 159.408 1.00 86.19  ? 25  GLU B N   1 
ATOM   3523  C CA  . GLU B 1 4   ? 189.182 201.579 158.778 1.00 86.19  ? 25  GLU B CA  1 
ATOM   3524  C C   . GLU B 1 4   ? 188.061 200.899 157.998 1.00 86.19  ? 25  GLU B C   1 
ATOM   3525  O O   . GLU B 1 4   ? 186.889 201.279 158.115 1.00 86.19  ? 25  GLU B O   1 
ATOM   3526  C CB  . GLU B 1 4   ? 189.993 202.499 157.866 1.00 86.19  ? 25  GLU B CB  1 
ATOM   3527  C CG  . GLU B 1 4   ? 190.695 203.639 158.590 1.00 86.19  ? 25  GLU B CG  1 
ATOM   3528  C CD  . GLU B 1 4   ? 191.975 203.202 159.274 1.00 86.19  ? 25  GLU B CD  1 
ATOM   3529  O OE1 . GLU B 1 4   ? 192.525 202.147 158.892 1.00 86.19  ? 25  GLU B OE1 1 
ATOM   3530  O OE2 . GLU B 1 4   ? 192.432 203.913 160.193 1.00 86.19  ? 25  GLU B OE2 1 
ATOM   3531  N N   . ARG B 1 5   ? 188.407 199.881 157.204 1.00 83.37  ? 26  ARG B N   1 
ATOM   3532  C CA  . ARG B 1 5   ? 187.402 199.129 156.456 1.00 83.37  ? 26  ARG B CA  1 
ATOM   3533  C C   . ARG B 1 5   ? 186.493 198.337 157.388 1.00 83.37  ? 26  ARG B C   1 
ATOM   3534  O O   . ARG B 1 5   ? 185.276 198.262 157.169 1.00 83.37  ? 26  ARG B O   1 
ATOM   3535  C CB  . ARG B 1 5   ? 188.090 198.198 155.459 1.00 83.37  ? 26  ARG B CB  1 
ATOM   3536  C CG  . ARG B 1 5   ? 189.165 198.859 154.612 1.00 83.37  ? 26  ARG B CG  1 
ATOM   3537  C CD  . ARG B 1 5   ? 189.611 197.939 153.485 1.00 83.37  ? 26  ARG B CD  1 
ATOM   3538  N NE  . ARG B 1 5   ? 188.516 197.578 152.592 1.00 83.37  ? 26  ARG B NE  1 
ATOM   3539  C CZ  . ARG B 1 5   ? 188.118 198.307 151.558 1.00 83.37  ? 26  ARG B CZ  1 
ATOM   3540  N NH1 . ARG B 1 5   ? 188.723 199.438 151.237 1.00 83.37  ? 26  ARG B NH1 1 
ATOM   3541  N NH2 . ARG B 1 5   ? 187.093 197.886 150.823 1.00 83.37  ? 26  ARG B NH2 1 
ATOM   3542  N N   . LEU B 1 6   ? 187.062 197.757 158.446 1.00 72.74  ? 27  LEU B N   1 
ATOM   3543  C CA  . LEU B 1 6   ? 186.264 197.005 159.404 1.00 72.74  ? 27  LEU B CA  1 
ATOM   3544  C C   . LEU B 1 6   ? 185.439 197.926 160.296 1.00 72.74  ? 27  LEU B C   1 
ATOM   3545  O O   . LEU B 1 6   ? 184.424 197.490 160.848 1.00 72.74  ? 27  LEU B O   1 
ATOM   3546  C CB  . LEU B 1 6   ? 187.187 196.095 160.224 1.00 72.74  ? 27  LEU B CB  1 
ATOM   3547  C CG  . LEU B 1 6   ? 186.636 194.917 161.032 1.00 72.74  ? 27  LEU B CG  1 
ATOM   3548  C CD1 . LEU B 1 6   ? 187.637 193.778 160.992 1.00 72.74  ? 27  LEU B CD1 1 
ATOM   3549  C CD2 . LEU B 1 6   ? 186.372 195.293 162.472 1.00 72.74  ? 27  LEU B CD2 1 
ATOM   3550  N N   . ALA B 1 7   ? 185.841 199.193 160.435 1.00 68.82  ? 28  ALA B N   1 
ATOM   3551  C CA  . ALA B 1 7   ? 184.997 200.186 161.087 1.00 68.82  ? 28  ALA B CA  1 
ATOM   3552  C C   . ALA B 1 7   ? 183.865 200.641 160.181 1.00 68.82  ? 28  ALA B C   1 
ATOM   3553  O O   . ALA B 1 7   ? 182.762 200.919 160.664 1.00 68.82  ? 28  ALA B O   1 
ATOM   3554  C CB  . ALA B 1 7   ? 185.835 201.387 161.525 1.00 68.82  ? 28  ALA B CB  1 
ATOM   3555  N N   . SER B 1 8   ? 184.122 200.729 158.875 1.00 80.57  ? 29  SER B N   1 
ATOM   3556  C CA  . SER B 1 8   ? 183.063 201.063 157.931 1.00 80.57  ? 29  SER B CA  1 
ATOM   3557  C C   . SER B 1 8   ? 182.076 199.919 157.739 1.00 80.57  ? 29  SER B C   1 
ATOM   3558  O O   . SER B 1 8   ? 180.930 200.168 157.349 1.00 80.57  ? 29  SER B O   1 
ATOM   3559  C CB  . SER B 1 8   ? 183.664 201.465 156.584 1.00 80.57  ? 29  SER B CB  1 
ATOM   3560  O OG  . SER B 1 8   ? 184.051 202.828 156.589 1.00 80.57  ? 29  SER B OG  1 
ATOM   3561  N N   . ILE B 1 9   ? 182.488 198.672 157.998 1.00 76.16  ? 30  ILE B N   1 
ATOM   3562  C CA  . ILE B 1 9   ? 181.556 197.549 157.912 1.00 76.16  ? 30  ILE B CA  1 
ATOM   3563  C C   . ILE B 1 9   ? 180.772 197.341 159.206 1.00 76.16  ? 30  ILE B C   1 
ATOM   3564  O O   . ILE B 1 9   ? 179.747 196.642 159.192 1.00 76.16  ? 30  ILE B O   1 
ATOM   3565  C CB  . ILE B 1 9   ? 182.300 196.263 157.484 1.00 76.16  ? 30  ILE B CB  1 
ATOM   3566  C CG1 . ILE B 1 9   ? 181.380 195.352 156.666 1.00 76.16  ? 30  ILE B CG1 1 
ATOM   3567  C CG2 . ILE B 1 9   ? 182.857 195.503 158.681 1.00 76.16  ? 30  ILE B CG2 1 
ATOM   3568  C CD1 . ILE B 1 9   ? 180.932 195.955 155.356 1.00 76.16  ? 30  ILE B CD1 1 
ATOM   3569  N N   . GLY B 1 10  ? 181.198 197.944 160.315 1.00 62.47  ? 31  GLY B N   1 
ATOM   3570  C CA  . GLY B 1 10  ? 180.419 197.882 161.537 1.00 62.47  ? 31  GLY B CA  1 
ATOM   3571  C C   . GLY B 1 10  ? 181.101 197.235 162.726 1.00 62.47  ? 31  GLY B C   1 
ATOM   3572  O O   . GLY B 1 10  ? 180.426 196.763 163.645 1.00 62.47  ? 31  GLY B O   1 
ATOM   3573  N N   . GLY B 1 11  ? 182.431 197.209 162.731 1.00 57.69  ? 32  GLY B N   1 
ATOM   3574  C CA  . GLY B 1 11  ? 183.165 196.654 163.854 1.00 57.69  ? 32  GLY B CA  1 
ATOM   3575  C C   . GLY B 1 11  ? 184.214 197.610 164.383 1.00 57.69  ? 32  GLY B C   1 
ATOM   3576  O O   . GLY B 1 11  ? 185.057 198.093 163.626 1.00 57.69  ? 32  GLY B O   1 
ATOM   3577  N N   . ILE B 1 12  ? 184.186 197.892 165.681 1.00 47.02  ? 33  ILE B N   1 
ATOM   3578  C CA  . ILE B 1 12  ? 185.015 198.931 166.278 1.00 47.02  ? 33  ILE B CA  1 
ATOM   3579  C C   . ILE B 1 12  ? 186.058 198.268 167.168 1.00 47.02  ? 33  ILE B C   1 
ATOM   3580  O O   . ILE B 1 12  ? 185.734 197.362 167.944 1.00 47.02  ? 33  ILE B O   1 
ATOM   3581  C CB  . ILE B 1 12  ? 184.149 199.937 167.054 1.00 47.02  ? 33  ILE B CB  1 
ATOM   3582  C CG1 . ILE B 1 12  ? 183.046 200.453 166.128 1.00 47.02  ? 33  ILE B CG1 1 
ATOM   3583  C CG2 . ILE B 1 12  ? 184.986 201.091 167.580 1.00 47.02  ? 33  ILE B CG2 1 
ATOM   3584  C CD1 . ILE B 1 12  ? 181.916 201.139 166.822 1.00 47.02  ? 33  ILE B CD1 1 
ATOM   3585  N N   . LYS B 1 13  ? 187.310 198.705 167.037 1.00 45.55  ? 34  LYS B N   1 
ATOM   3586  C CA  . LYS B 1 13  ? 188.416 198.093 167.764 1.00 45.55  ? 34  LYS B CA  1 
ATOM   3587  C C   . LYS B 1 13  ? 188.338 198.439 169.247 1.00 45.55  ? 34  LYS B C   1 
ATOM   3588  O O   . LYS B 1 13  ? 188.314 199.617 169.619 1.00 45.55  ? 34  LYS B O   1 
ATOM   3589  C CB  . LYS B 1 13  ? 189.745 198.554 167.170 1.00 45.55  ? 34  LYS B CB  1 
ATOM   3590  C CG  . LYS B 1 13  ? 190.970 198.106 167.946 1.00 45.55  ? 34  LYS B CG  1 
ATOM   3591  C CD  . LYS B 1 13  ? 192.227 198.779 167.418 1.00 45.55  ? 34  LYS B CD  1 
ATOM   3592  C CE  . LYS B 1 13  ? 192.510 200.079 168.149 1.00 45.55  ? 34  LYS B CE  1 
ATOM   3593  N NZ  . LYS B 1 13  ? 192.543 199.888 169.624 1.00 45.55  ? 34  LYS B NZ  1 
ATOM   3594  N N   . GLY B 1 14  ? 188.297 197.414 170.089 1.00 39.65  ? 35  GLY B N   1 
ATOM   3595  C CA  . GLY B 1 14  ? 188.218 197.576 171.527 1.00 39.65  ? 35  GLY B CA  1 
ATOM   3596  C C   . GLY B 1 14  ? 189.575 197.550 172.193 1.00 39.65  ? 35  GLY B C   1 
ATOM   3597  O O   . GLY B 1 14  ? 190.584 197.975 171.622 1.00 39.65  ? 35  GLY B O   1 
ATOM   3598  N N   . HIS B 1 15  ? 189.599 197.043 173.425 1.00 37.90  ? 36  HIS B N   1 
ATOM   3599  C CA  . HIS B 1 15  ? 190.831 196.985 174.197 1.00 37.90  ? 36  HIS B CA  1 
ATOM   3600  C C   . HIS B 1 15  ? 191.780 195.927 173.638 1.00 37.90  ? 36  HIS B C   1 
ATOM   3601  O O   . HIS B 1 15  ? 191.379 194.996 172.936 1.00 37.90  ? 36  HIS B O   1 
ATOM   3602  C CB  . HIS B 1 15  ? 190.541 196.677 175.668 1.00 37.90  ? 36  HIS B CB  1 
ATOM   3603  C CG  . HIS B 1 15  ? 189.331 197.369 176.211 1.00 37.90  ? 36  HIS B CG  1 
ATOM   3604  N ND1 . HIS B 1 15  ? 188.062 196.840 176.112 1.00 37.90  ? 36  HIS B ND1 1 
ATOM   3605  C CD2 . HIS B 1 15  ? 189.198 198.542 176.874 1.00 37.90  ? 36  HIS B CD2 1 
ATOM   3606  C CE1 . HIS B 1 15  ? 187.199 197.661 176.683 1.00 37.90  ? 36  HIS B CE1 1 
ATOM   3607  N NE2 . HIS B 1 15  ? 187.862 198.701 177.153 1.00 37.90  ? 36  HIS B NE2 1 
ATOM   3608  N N   . SER B 1 16  ? 193.059 196.090 173.961 1.00 36.47  ? 37  SER B N   1 
ATOM   3609  C CA  . SER B 1 16  ? 194.097 195.125 173.623 1.00 36.47  ? 37  SER B CA  1 
ATOM   3610  C C   . SER B 1 16  ? 194.629 194.527 174.918 1.00 36.47  ? 37  SER B C   1 
ATOM   3611  O O   . SER B 1 16  ? 195.085 195.261 175.801 1.00 36.47  ? 37  SER B O   1 
ATOM   3612  C CB  . SER B 1 16  ? 195.222 195.784 172.827 1.00 36.47  ? 37  SER B CB  1 
ATOM   3613  O OG  . SER B 1 16  ? 194.748 196.272 171.584 1.00 36.47  ? 37  SER B OG  1 
ATOM   3614  N N   . LYS B 1 17  ? 194.573 193.203 175.027 1.00 38.52  ? 38  LYS B N   1 
ATOM   3615  C CA  . LYS B 1 17  ? 194.950 192.508 176.248 1.00 38.52  ? 38  LYS B CA  1 
ATOM   3616  C C   . LYS B 1 17  ? 196.014 191.464 175.943 1.00 38.52  ? 38  LYS B C   1 
ATOM   3617  O O   . LYS B 1 17  ? 196.151 190.994 174.811 1.00 38.52  ? 38  LYS B O   1 
ATOM   3618  C CB  . LYS B 1 17  ? 193.736 191.843 176.914 1.00 38.52  ? 38  LYS B CB  1 
ATOM   3619  C CG  . LYS B 1 17  ? 192.674 192.821 177.386 1.00 38.52  ? 38  LYS B CG  1 
ATOM   3620  C CD  . LYS B 1 17  ? 191.496 192.096 178.009 1.00 38.52  ? 38  LYS B CD  1 
ATOM   3621  C CE  . LYS B 1 17  ? 190.368 193.057 178.344 1.00 38.52  ? 38  LYS B CE  1 
ATOM   3622  N NZ  . LYS B 1 17  ? 190.740 193.986 179.446 1.00 38.52  ? 38  LYS B NZ  1 
ATOM   3623  N N   . LEU B 1 18  ? 196.773 191.109 176.978 1.00 38.16  ? 39  LEU B N   1 
ATOM   3624  C CA  . LEU B 1 18  ? 197.849 190.140 176.858 1.00 38.16  ? 39  LEU B CA  1 
ATOM   3625  C C   . LEU B 1 18  ? 197.298 188.723 177.010 1.00 38.16  ? 39  LEU B C   1 
ATOM   3626  O O   . LEU B 1 18  ? 196.093 188.507 177.158 1.00 38.16  ? 39  LEU B O   1 
ATOM   3627  C CB  . LEU B 1 18  ? 198.942 190.422 177.889 1.00 38.16  ? 39  LEU B CB  1 
ATOM   3628  C CG  . LEU B 1 18  ? 200.037 191.438 177.545 1.00 38.16  ? 39  LEU B CG  1 
ATOM   3629  C CD1 . LEU B 1 18  ? 199.553 192.878 177.668 1.00 38.16  ? 39  LEU B CD1 1 
ATOM   3630  C CD2 . LEU B 1 18  ? 201.251 191.213 178.428 1.00 38.16  ? 39  LEU B CD2 1 
ATOM   3631  N N   . TYR B 1 19  ? 198.195 187.739 176.978 1.00 40.08  ? 40  TYR B N   1 
ATOM   3632  C CA  . TYR B 1 19  ? 197.808 186.336 177.036 1.00 40.08  ? 40  TYR B CA  1 
ATOM   3633  C C   . TYR B 1 19  ? 198.788 185.589 177.926 1.00 40.08  ? 40  TYR B C   1 
ATOM   3634  O O   . TYR B 1 19  ? 200.001 185.661 177.709 1.00 40.08  ? 40  TYR B O   1 
ATOM   3635  C CB  . TYR B 1 19  ? 197.778 185.729 175.628 1.00 40.08  ? 40  TYR B CB  1 
ATOM   3636  C CG  . TYR B 1 19  ? 197.045 184.413 175.517 1.00 40.08  ? 40  TYR B CG  1 
ATOM   3637  C CD1 . TYR B 1 19  ? 195.974 184.119 176.352 1.00 40.08  ? 40  TYR B CD1 1 
ATOM   3638  C CD2 . TYR B 1 19  ? 197.407 183.475 174.557 1.00 40.08  ? 40  TYR B CD2 1 
ATOM   3639  C CE1 . TYR B 1 19  ? 195.295 182.917 176.246 1.00 40.08  ? 40  TYR B CE1 1 
ATOM   3640  C CE2 . TYR B 1 19  ? 196.736 182.273 174.442 1.00 40.08  ? 40  TYR B CE2 1 
ATOM   3641  C CZ  . TYR B 1 19  ? 195.681 182.000 175.289 1.00 40.08  ? 40  TYR B CZ  1 
ATOM   3642  O OH  . TYR B 1 19  ? 195.010 180.805 175.178 1.00 40.08  ? 40  TYR B OH  1 
ATOM   3643  N N   . LYS B 1 20  ? 198.267 184.876 178.923 1.00 40.50  ? 41  LYS B N   1 
ATOM   3644  C CA  . LYS B 1 20  ? 199.104 184.157 179.874 1.00 40.50  ? 41  LYS B CA  1 
ATOM   3645  C C   . LYS B 1 20  ? 198.536 182.768 180.121 1.00 40.50  ? 41  LYS B C   1 
ATOM   3646  O O   . LYS B 1 20  ? 197.318 182.588 180.197 1.00 40.50  ? 41  LYS B O   1 
ATOM   3647  C CB  . LYS B 1 20  ? 199.226 184.921 181.198 1.00 40.50  ? 41  LYS B CB  1 
ATOM   3648  C CG  . LYS B 1 20  ? 200.389 185.903 181.228 1.00 40.50  ? 41  LYS B CG  1 
ATOM   3649  C CD  . LYS B 1 20  ? 200.368 186.783 182.470 1.00 40.50  ? 41  LYS B CD  1 
ATOM   3650  C CE  . LYS B 1 20  ? 199.032 187.482 182.644 1.00 40.50  ? 41  LYS B CE  1 
ATOM   3651  N NZ  . LYS B 1 20  ? 198.904 188.089 183.995 1.00 40.50  ? 41  LYS B NZ  1 
ATOM   3652  N N   . ILE B 1 21  ? 199.433 181.789 180.243 1.00 51.10  ? 42  ILE B N   1 
ATOM   3653  C CA  . ILE B 1 21  ? 199.079 180.383 180.405 1.00 51.10  ? 42  ILE B CA  1 
ATOM   3654  C C   . ILE B 1 21  ? 199.713 179.876 181.695 1.00 51.10  ? 42  ILE B C   1 
ATOM   3655  O O   . ILE B 1 21  ? 200.848 180.242 182.022 1.00 51.10  ? 42  ILE B O   1 
ATOM   3656  C CB  . ILE B 1 21  ? 199.546 179.538 179.195 1.00 51.10  ? 42  ILE B CB  1 
ATOM   3657  C CG1 . ILE B 1 21  ? 199.102 180.171 177.876 1.00 51.10  ? 42  ILE B CG1 1 
ATOM   3658  C CG2 . ILE B 1 21  ? 198.996 178.119 179.254 1.00 51.10  ? 42  ILE B CG2 1 
ATOM   3659  C CD1 . ILE B 1 21  ? 199.736 179.540 176.657 1.00 51.10  ? 42  ILE B CD1 1 
ATOM   3660  N N   . LYS B 1 22  ? 198.967 179.066 182.445 1.00 57.57  ? 43  LYS B N   1 
ATOM   3661  C CA  . LYS B 1 22  ? 199.545 178.324 183.559 1.00 57.57  ? 43  LYS B CA  1 
ATOM   3662  C C   . LYS B 1 22  ? 200.572 177.319 183.050 1.00 57.57  ? 43  LYS B C   1 
ATOM   3663  O O   . LYS B 1 22  ? 200.330 176.600 182.077 1.00 57.57  ? 43  LYS B O   1 
ATOM   3664  C CB  . LYS B 1 22  ? 198.448 177.596 184.336 1.00 57.57  ? 43  LYS B CB  1 
ATOM   3665  C CG  . LYS B 1 22  ? 198.932 176.877 185.585 1.00 57.57  ? 43  LYS B CG  1 
ATOM   3666  C CD  . LYS B 1 22  ? 197.856 175.963 186.152 1.00 57.57  ? 43  LYS B CD  1 
ATOM   3667  C CE  . LYS B 1 22  ? 197.901 174.586 185.508 1.00 57.57  ? 43  LYS B CE  1 
ATOM   3668  N NZ  . LYS B 1 22  ? 199.100 173.808 185.924 1.00 57.57  ? 43  LYS B NZ  1 
ATOM   3669  N N   . GLY B 1 23  ? 201.724 177.270 183.711 1.00 70.80  ? 44  GLY B N   1 
ATOM   3670  C CA  . GLY B 1 23  ? 202.768 176.345 183.305 1.00 70.80  ? 44  GLY B CA  1 
ATOM   3671  C C   . GLY B 1 23  ? 203.849 176.254 184.357 1.00 70.80  ? 44  GLY B C   1 
ATOM   3672  O O   . GLY B 1 23  ? 203.940 177.092 185.259 1.00 70.80  ? 44  GLY B O   1 
ATOM   3673  N N   . HIS B 1 24  ? 204.688 175.218 184.202 1.00 93.33  ? 45  HIS B N   1 
ATOM   3674  C CA  . HIS B 1 24  ? 205.780 174.817 185.093 1.00 93.33  ? 45  HIS B CA  1 
ATOM   3675  C C   . HIS B 1 24  ? 205.288 174.668 186.533 1.00 93.33  ? 45  HIS B C   1 
ATOM   3676  O O   . HIS B 1 24  ? 205.499 175.567 187.359 1.00 93.33  ? 45  HIS B O   1 
ATOM   3677  C CB  . HIS B 1 24  ? 206.942 175.815 184.999 1.00 93.33  ? 45  HIS B CB  1 
ATOM   3678  C CG  . HIS B 1 24  ? 208.133 175.446 185.832 1.00 93.33  ? 45  HIS B CG  1 
ATOM   3679  N ND1 . HIS B 1 24  ? 208.992 174.425 185.491 1.00 93.33  ? 45  HIS B ND1 1 
ATOM   3680  C CD2 . HIS B 1 24  ? 208.606 175.965 186.990 1.00 93.33  ? 45  HIS B CD2 1 
ATOM   3681  C CE1 . HIS B 1 24  ? 209.943 174.329 186.404 1.00 93.33  ? 45  HIS B CE1 1 
ATOM   3682  N NE2 . HIS B 1 24  ? 209.731 175.252 187.324 1.00 93.33  ? 45  HIS B NE2 1 
ATOM   3683  N N   . PRO B 1 25  ? 204.576 173.590 186.866 1.00 66.11  ? 46  PRO B N   1 
ATOM   3684  C CA  . PRO B 1 25  ? 204.080 173.444 188.238 1.00 66.11  ? 46  PRO B CA  1 
ATOM   3685  C C   . PRO B 1 25  ? 205.009 172.646 189.141 1.00 66.11  ? 46  PRO B C   1 
ATOM   3686  O O   . PRO B 1 25  ? 205.599 171.636 188.751 1.00 66.11  ? 46  PRO B O   1 
ATOM   3687  C CB  . PRO B 1 25  ? 202.750 172.706 188.036 1.00 66.11  ? 46  PRO B CB  1 
ATOM   3688  C CG  . PRO B 1 25  ? 202.933 171.918 186.766 1.00 66.11  ? 46  PRO B CG  1 
ATOM   3689  C CD  . PRO B 1 25  ? 204.091 172.504 185.993 1.00 66.11  ? 46  PRO B CD  1 
ATOM   3690  N N   . THR B 1 26  ? 205.139 173.117 190.375 1.00 46.15  ? 47  THR B N   1 
ATOM   3691  C CA  . THR B 1 26  ? 205.764 172.346 191.438 1.00 46.15  ? 47  THR B CA  1 
ATOM   3692  C C   . THR B 1 26  ? 204.682 171.657 192.261 1.00 46.15  ? 47  THR B C   1 
ATOM   3693  O O   . THR B 1 26  ? 203.505 172.021 192.210 1.00 46.15  ? 47  THR B O   1 
ATOM   3694  C CB  . THR B 1 26  ? 206.641 173.233 192.329 1.00 46.15  ? 47  THR B CB  1 
ATOM   3695  O OG1 . THR B 1 26  ? 207.296 172.424 193.314 1.00 46.15  ? 47  THR B OG1 1 
ATOM   3696  C CG2 . THR B 1 26  ? 205.811 174.298 193.022 1.00 46.15  ? 47  THR B CG2 1 
ATOM   3697  N N   . THR B 1 27  ? 205.088 170.642 193.015 1.00 41.52  ? 48  THR B N   1 
ATOM   3698  C CA  . THR B 1 27  ? 204.152 169.785 193.724 1.00 41.52  ? 48  THR B CA  1 
ATOM   3699  C C   . THR B 1 27  ? 204.282 169.980 195.227 1.00 41.52  ? 48  THR B C   1 
ATOM   3700  O O   . THR B 1 27  ? 205.386 170.174 195.744 1.00 41.52  ? 48  THR B O   1 
ATOM   3701  C CB  . THR B 1 27  ? 204.385 168.313 193.380 1.00 41.52  ? 48  THR B CB  1 
ATOM   3702  O OG1 . THR B 1 27  ? 205.763 167.985 193.590 1.00 41.52  ? 48  THR B OG1 1 
ATOM   3703  C CG2 . THR B 1 27  ? 204.021 168.044 191.930 1.00 41.52  ? 48  THR B CG2 1 
ATOM   3704  N N   . LYS B 1 28  ? 203.148 169.932 195.922 1.00 29.70  ? 49  LYS B N   1 
ATOM   3705  C CA  . LYS B 1 28  ? 203.136 169.959 197.377 1.00 29.70  ? 49  LYS B CA  1 
ATOM   3706  C C   . LYS B 1 28  ? 202.089 168.976 197.886 1.00 29.70  ? 49  LYS B C   1 
ATOM   3707  O O   . LYS B 1 28  ? 201.009 168.844 197.299 1.00 29.70  ? 49  LYS B O   1 
ATOM   3708  C CB  . LYS B 1 28  ? 202.869 171.374 197.904 1.00 29.70  ? 49  LYS B CB  1 
ATOM   3709  C CG  . LYS B 1 28  ? 203.043 171.518 199.405 1.00 29.70  ? 49  LYS B CG  1 
ATOM   3710  C CD  . LYS B 1 28  ? 202.818 172.937 199.854 1.00 29.70  ? 49  LYS B CD  1 
ATOM   3711  C CE  . LYS B 1 28  ? 203.959 173.844 199.429 1.00 29.70  ? 49  LYS B CE  1 
ATOM   3712  N NZ  . LYS B 1 28  ? 205.225 173.516 200.140 1.00 29.70  ? 49  LYS B NZ  1 
ATOM   3713  N N   . ASP B 1 29  ? 202.415 168.288 198.977 1.00 28.76  ? 50  ASP B N   1 
ATOM   3714  C CA  . ASP B 1 29  ? 201.613 167.192 199.500 1.00 28.76  ? 50  ASP B CA  1 
ATOM   3715  C C   . ASP B 1 29  ? 200.800 167.657 200.699 1.00 28.76  ? 50  ASP B C   1 
ATOM   3716  O O   . ASP B 1 29  ? 201.340 168.280 201.619 1.00 28.76  ? 50  ASP B O   1 
ATOM   3717  C CB  . ASP B 1 29  ? 202.506 166.019 199.905 1.00 28.76  ? 50  ASP B CB  1 
ATOM   3718  C CG  . ASP B 1 29  ? 203.049 165.268 198.712 1.00 28.76  ? 50  ASP B CG  1 
ATOM   3719  O OD1 . ASP B 1 29  ? 202.258 164.933 197.807 1.00 28.76  ? 50  ASP B OD1 1 
ATOM   3720  O OD2 . ASP B 1 29  ? 204.270 165.021 198.672 1.00 28.76  ? 50  ASP B OD2 1 
ATOM   3721  N N   . ILE B 1 30  ? 199.504 167.353 200.684 1.00 27.12  ? 51  ILE B N   1 
ATOM   3722  C CA  . ILE B 1 30  ? 198.625 167.562 201.824 1.00 27.12  ? 51  ILE B CA  1 
ATOM   3723  C C   . ILE B 1 30  ? 198.001 166.219 202.178 1.00 27.12  ? 51  ILE B C   1 
ATOM   3724  O O   . ILE B 1 30  ? 198.044 165.263 201.401 1.00 27.12  ? 51  ILE B O   1 
ATOM   3725  C CB  . ILE B 1 30  ? 197.531 168.616 201.548 1.00 27.12  ? 51  ILE B CB  1 
ATOM   3726  C CG1 . ILE B 1 30  ? 196.615 168.155 200.417 1.00 27.12  ? 51  ILE B CG1 1 
ATOM   3727  C CG2 . ILE B 1 30  ? 198.146 169.956 201.195 1.00 27.12  ? 51  ILE B CG2 1 
ATOM   3728  C CD1 . ILE B 1 30  ? 195.413 169.049 200.217 1.00 27.12  ? 51  ILE B CD1 1 
ATOM   3729  N N   . VAL B 1 31  ? 197.444 166.138 203.382 1.00 49.69  ? 52  VAL B N   1 
ATOM   3730  C CA  . VAL B 1 31  ? 196.718 164.954 203.823 1.00 49.69  ? 52  VAL B CA  1 
ATOM   3731  C C   . VAL B 1 31  ? 195.367 165.378 204.376 1.00 49.69  ? 52  VAL B C   1 
ATOM   3732  O O   . VAL B 1 31  ? 195.250 166.412 205.044 1.00 49.69  ? 52  VAL B O   1 
ATOM   3733  C CB  . VAL B 1 31  ? 197.511 164.126 204.859 1.00 49.69  ? 52  VAL B CB  1 
ATOM   3734  C CG1 . VAL B 1 31  ? 198.668 163.424 204.195 1.00 49.69  ? 52  VAL B CG1 1 
ATOM   3735  C CG2 . VAL B 1 31  ? 198.052 165.009 205.951 1.00 49.69  ? 52  VAL B CG2 1 
ATOM   3736  N N   . ILE B 1 32  ? 194.338 164.597 204.061 1.00 49.69  ? 53  ILE B N   1 
ATOM   3737  C CA  . ILE B 1 32  ? 192.976 164.853 204.512 1.00 49.69  ? 53  ILE B CA  1 
ATOM   3738  C C   . ILE B 1 32  ? 192.498 163.632 205.277 1.00 49.69  ? 53  ILE B C   1 
ATOM   3739  O O   . ILE B 1 32  ? 192.395 162.538 204.710 1.00 49.69  ? 53  ILE B O   1 
ATOM   3740  C CB  . ILE B 1 32  ? 192.031 165.157 203.340 1.00 49.69  ? 53  ILE B CB  1 
ATOM   3741  C CG1 . ILE B 1 32  ? 192.504 166.390 202.573 1.00 49.69  ? 53  ILE B CG1 1 
ATOM   3742  C CG2 . ILE B 1 32  ? 190.611 165.344 203.840 1.00 49.69  ? 53  ILE B CG2 1 
ATOM   3743  C CD1 . ILE B 1 32  ? 191.893 166.512 201.210 1.00 49.69  ? 53  ILE B CD1 1 
ATOM   3744  N N   . LYS B 1 33  ? 192.207 163.815 206.557 1.00 26.53  ? 54  LYS B N   1 
ATOM   3745  C CA  . LYS B 1 33  ? 191.576 162.774 207.349 1.00 26.53  ? 54  LYS B CA  1 
ATOM   3746  C C   . LYS B 1 33  ? 190.060 162.907 207.246 1.00 26.53  ? 54  LYS B C   1 
ATOM   3747  O O   . LYS B 1 33  ? 189.527 163.979 206.955 1.00 26.53  ? 54  LYS B O   1 
ATOM   3748  C CB  . LYS B 1 33  ? 192.053 162.852 208.801 1.00 26.53  ? 54  LYS B CB  1 
ATOM   3749  C CG  . LYS B 1 33  ? 191.622 164.103 209.541 1.00 26.53  ? 54  LYS B CG  1 
ATOM   3750  C CD  . LYS B 1 33  ? 192.239 164.161 210.927 1.00 26.53  ? 54  LYS B CD  1 
ATOM   3751  C CE  . LYS B 1 33  ? 191.625 163.133 211.855 1.00 26.53  ? 54  LYS B CE  1 
ATOM   3752  N NZ  . LYS B 1 33  ? 192.161 163.262 213.237 1.00 26.53  ? 54  LYS B NZ  1 
ATOM   3753  N N   . LEU B 1 34  ? 189.366 161.792 207.455 1.00 24.49  ? 55  LEU B N   1 
ATOM   3754  C CA  . LEU B 1 34  ? 187.928 161.744 207.224 1.00 24.49  ? 55  LEU B CA  1 
ATOM   3755  C C   . LEU B 1 34  ? 187.108 161.424 208.463 1.00 24.49  ? 55  LEU B C   1 
ATOM   3756  O O   . LEU B 1 34  ? 185.940 161.812 208.523 1.00 24.49  ? 55  LEU B O   1 
ATOM   3757  C CB  . LEU B 1 34  ? 187.600 160.715 206.129 1.00 24.49  ? 55  LEU B CB  1 
ATOM   3758  C CG  . LEU B 1 34  ? 187.876 161.132 204.681 1.00 24.49  ? 55  LEU B CG  1 
ATOM   3759  C CD1 . LEU B 1 34  ? 187.173 160.198 203.712 1.00 24.49  ? 55  LEU B CD1 1 
ATOM   3760  C CD2 . LEU B 1 34  ? 187.462 162.575 204.424 1.00 24.49  ? 55  LEU B CD2 1 
ATOM   3761  N N   . VAL B 1 35  ? 187.675 160.731 209.443 1.00 28.83  ? 56  VAL B N   1 
ATOM   3762  C CA  . VAL B 1 35  ? 186.991 160.443 210.699 1.00 28.83  ? 56  VAL B CA  1 
ATOM   3763  C C   . VAL B 1 35  ? 187.371 161.533 211.697 1.00 28.83  ? 56  VAL B C   1 
ATOM   3764  O O   . VAL B 1 35  ? 188.571 161.734 211.941 1.00 28.83  ? 56  VAL B O   1 
ATOM   3765  C CB  . VAL B 1 35  ? 187.361 159.056 211.233 1.00 28.83  ? 56  VAL B CB  1 
ATOM   3766  C CG1 . VAL B 1 35  ? 186.765 158.842 212.615 1.00 28.83  ? 56  VAL B CG1 1 
ATOM   3767  C CG2 . VAL B 1 35  ? 186.890 157.983 210.271 1.00 28.83  ? 56  VAL B CG2 1 
ATOM   3768  N N   . PRO B 1 36  ? 186.409 162.259 212.269 1.00 30.73  ? 57  PRO B N   1 
ATOM   3769  C CA  . PRO B 1 36  ? 186.756 163.329 213.212 1.00 30.73  ? 57  PRO B CA  1 
ATOM   3770  C C   . PRO B 1 36  ? 187.278 162.779 214.530 1.00 30.73  ? 57  PRO B C   1 
ATOM   3771  O O   . PRO B 1 36  ? 186.761 161.797 215.068 1.00 30.73  ? 57  PRO B O   1 
ATOM   3772  C CB  . PRO B 1 36  ? 185.430 164.073 213.402 1.00 30.73  ? 57  PRO B CB  1 
ATOM   3773  C CG  . PRO B 1 36  ? 184.387 163.050 213.111 1.00 30.73  ? 57  PRO B CG  1 
ATOM   3774  C CD  . PRO B 1 36  ? 184.959 162.189 212.021 1.00 30.73  ? 57  PRO B CD  1 
ATOM   3775  N N   . ASN B 1 37  ? 188.318 163.427 215.045 1.00 42.66  ? 58  ASN B N   1 
ATOM   3776  C CA  . ASN B 1 37  ? 188.956 163.017 216.290 1.00 42.66  ? 58  ASN B CA  1 
ATOM   3777  C C   . ASN B 1 37  ? 188.217 163.665 217.453 1.00 42.66  ? 58  ASN B C   1 
ATOM   3778  O O   . ASN B 1 37  ? 188.261 164.887 217.624 1.00 42.66  ? 58  ASN B O   1 
ATOM   3779  C CB  . ASN B 1 37  ? 190.432 163.405 216.294 1.00 42.66  ? 58  ASN B CB  1 
ATOM   3780  C CG  . ASN B 1 37  ? 191.131 163.030 217.587 1.00 42.66  ? 58  ASN B CG  1 
ATOM   3781  O OD1 . ASN B 1 37  ? 190.823 162.009 218.201 1.00 42.66  ? 58  ASN B OD1 1 
ATOM   3782  N ND2 . ASN B 1 37  ? 192.079 163.860 218.008 1.00 42.66  ? 58  ASN B ND2 1 
ATOM   3783  N N   . LEU B 1 38  ? 187.540 162.847 218.254 1.00 52.64  ? 59  LEU B N   1 
ATOM   3784  C CA  . LEU B 1 38  ? 186.820 163.317 219.427 1.00 52.64  ? 59  LEU B CA  1 
ATOM   3785  C C   . LEU B 1 38  ? 187.439 162.699 220.673 1.00 52.64  ? 59  LEU B C   1 
ATOM   3786  O O   . LEU B 1 38  ? 187.668 161.486 220.725 1.00 52.64  ? 59  LEU B O   1 
ATOM   3787  C CB  . LEU B 1 38  ? 185.318 163.001 219.310 1.00 52.64  ? 59  LEU B CB  1 
ATOM   3788  C CG  . LEU B 1 38  ? 184.758 161.588 219.087 1.00 52.64  ? 59  LEU B CG  1 
ATOM   3789  C CD1 . LEU B 1 38  ? 184.448 160.850 220.387 1.00 52.64  ? 59  LEU B CD1 1 
ATOM   3790  C CD2 . LEU B 1 38  ? 183.522 161.650 218.202 1.00 52.64  ? 59  LEU B CD2 1 
ATOM   3791  N N   . ASN B 1 39  ? 187.749 163.545 221.653 1.00 63.84  ? 60  ASN B N   1 
ATOM   3792  C CA  . ASN B 1 39  ? 188.273 163.092 222.935 1.00 63.84  ? 60  ASN B CA  1 
ATOM   3793  C C   . ASN B 1 39  ? 187.589 163.725 224.134 1.00 63.84  ? 60  ASN B C   1 
ATOM   3794  O O   . ASN B 1 39  ? 187.632 163.137 225.222 1.00 63.84  ? 60  ASN B O   1 
ATOM   3795  C CB  . ASN B 1 39  ? 189.784 163.359 223.026 1.00 63.84  ? 60  ASN B CB  1 
ATOM   3796  C CG  . ASN B 1 39  ? 190.604 162.320 222.285 1.00 63.84  ? 60  ASN B CG  1 
ATOM   3797  O OD1 . ASN B 1 39  ? 190.262 161.138 222.270 1.00 63.84  ? 60  ASN B OD1 1 
ATOM   3798  N ND2 . ASN B 1 39  ? 191.693 162.759 221.664 1.00 63.84  ? 60  ASN B ND2 1 
ATOM   3799  N N   . ASN B 1 40  ? 186.968 164.897 223.983 1.00 74.77  ? 61  ASN B N   1 
ATOM   3800  C CA  . ASN B 1 40  ? 186.106 165.430 225.030 1.00 74.77  ? 61  ASN B CA  1 
ATOM   3801  C C   . ASN B 1 40  ? 184.833 164.611 225.188 1.00 74.77  ? 61  ASN B C   1 
ATOM   3802  O O   . ASN B 1 40  ? 184.272 164.550 226.287 1.00 74.77  ? 61  ASN B O   1 
ATOM   3803  C CB  . ASN B 1 40  ? 185.745 166.886 224.733 1.00 74.77  ? 61  ASN B CB  1 
ATOM   3804  C CG  . ASN B 1 40  ? 186.907 167.839 224.939 1.00 74.77  ? 61  ASN B CG  1 
ATOM   3805  O OD1 . ASN B 1 40  ? 187.378 168.476 223.997 1.00 74.77  ? 61  ASN B OD1 1 
ATOM   3806  N ND2 . ASN B 1 40  ? 187.365 167.951 226.183 1.00 74.77  ? 61  ASN B ND2 1 
ATOM   3807  N N   . LEU B 1 41  ? 184.370 163.972 224.111 1.00 69.52  ? 62  LEU B N   1 
ATOM   3808  C CA  . LEU B 1 41  ? 183.101 163.255 224.102 1.00 69.52  ? 62  LEU B CA  1 
ATOM   3809  C C   . LEU B 1 41  ? 183.254 161.777 224.433 1.00 69.52  ? 62  LEU B C   1 
ATOM   3810  O O   . LEU B 1 41  ? 182.452 160.958 223.969 1.00 69.52  ? 62  LEU B O   1 
ATOM   3811  C CB  . LEU B 1 41  ? 182.398 163.422 222.752 1.00 69.52  ? 62  LEU B CB  1 
ATOM   3812  C CG  . LEU B 1 41  ? 181.595 164.694 222.442 1.00 69.52  ? 62  LEU B CG  1 
ATOM   3813  C CD1 . LEU B 1 41  ? 182.460 165.929 222.200 1.00 69.52  ? 62  LEU B CD1 1 
ATOM   3814  C CD2 . LEU B 1 41  ? 180.672 164.447 221.259 1.00 69.52  ? 62  LEU B CD2 1 
ATOM   3815  N N   . THR B 1 42  ? 184.257 161.409 225.233 1.00 78.66  ? 63  THR B N   1 
ATOM   3816  C CA  . THR B 1 42  ? 184.399 160.022 225.661 1.00 78.66  ? 63  THR B CA  1 
ATOM   3817  C C   . THR B 1 42  ? 183.364 159.613 226.705 1.00 78.66  ? 63  THR B C   1 
ATOM   3818  O O   . THR B 1 42  ? 183.252 158.420 227.003 1.00 78.66  ? 63  THR B O   1 
ATOM   3819  C CB  . THR B 1 42  ? 185.808 159.780 226.209 1.00 78.66  ? 63  THR B CB  1 
ATOM   3820  O OG1 . THR B 1 42  ? 185.996 158.379 226.449 1.00 78.66  ? 63  THR B OG1 1 
ATOM   3821  C CG2 . THR B 1 42  ? 186.024 160.548 227.505 1.00 78.66  ? 63  THR B CG2 1 
ATOM   3822  N N   . VAL B 1 43  ? 182.614 160.564 227.263 1.00 82.96  ? 64  VAL B N   1 
ATOM   3823  C CA  . VAL B 1 43  ? 181.588 160.234 228.246 1.00 82.96  ? 64  VAL B CA  1 
ATOM   3824  C C   . VAL B 1 43  ? 180.309 159.773 227.559 1.00 82.96  ? 64  VAL B C   1 
ATOM   3825  O O   . VAL B 1 43  ? 179.768 158.707 227.874 1.00 82.96  ? 64  VAL B O   1 
ATOM   3826  C CB  . VAL B 1 43  ? 181.332 161.442 229.166 1.00 82.96  ? 64  VAL B CB  1 
ATOM   3827  C CG1 . VAL B 1 43  ? 180.193 161.149 230.129 1.00 82.96  ? 64  VAL B CG1 1 
ATOM   3828  C CG2 . VAL B 1 43  ? 182.599 161.810 229.923 1.00 82.96  ? 64  VAL B CG2 1 
ATOM   3829  N N   . CYS B 1 44  ? 179.807 160.560 226.606 1.00 96.32  ? 65  CYS B N   1 
ATOM   3830  C CA  . CYS B 1 44  ? 178.528 160.290 225.946 1.00 96.32  ? 65  CYS B CA  1 
ATOM   3831  C C   . CYS B 1 44  ? 178.683 160.440 224.434 1.00 96.32  ? 65  CYS B C   1 
ATOM   3832  O O   . CYS B 1 44  ? 178.407 161.505 223.875 1.00 96.32  ? 65  CYS B O   1 
ATOM   3833  C CB  . CYS B 1 44  ? 177.441 161.216 226.483 1.00 96.32  ? 65  CYS B CB  1 
ATOM   3834  S SG  . CYS B 1 44  ? 176.833 160.808 228.130 1.00 96.32  ? 65  CYS B SG  1 
ATOM   3835  N N   . SER B 1 45  ? 179.116 159.367 223.773 1.00 105.26 ? 66  SER B N   1 
ATOM   3836  C CA  . SER B 1 45  ? 179.094 159.315 222.316 1.00 105.26 ? 66  SER B CA  1 
ATOM   3837  C C   . SER B 1 45  ? 178.551 158.009 221.763 1.00 105.26 ? 66  SER B C   1 
ATOM   3838  O O   . SER B 1 45  ? 178.240 157.965 220.567 1.00 105.26 ? 66  SER B O   1 
ATOM   3839  C CB  . SER B 1 45  ? 180.498 159.545 221.740 1.00 105.26 ? 66  SER B CB  1 
ATOM   3840  O OG  . SER B 1 45  ? 181.471 158.810 222.462 1.00 105.26 ? 66  SER B OG  1 
ATOM   3841  N N   . GLU B 1 46  ? 178.421 156.966 222.582 1.00 100.42 ? 67  GLU B N   1 
ATOM   3842  C CA  . GLU B 1 46  ? 177.989 155.601 222.239 1.00 100.42 ? 67  GLU B CA  1 
ATOM   3843  C C   . GLU B 1 46  ? 178.921 155.053 221.154 1.00 100.42 ? 67  GLU B C   1 
ATOM   3844  O O   . GLU B 1 46  ? 180.130 155.318 221.165 1.00 100.42 ? 67  GLU B O   1 
ATOM   3845  C CB  . GLU B 1 46  ? 176.509 155.581 221.881 1.00 100.42 ? 67  GLU B CB  1 
ATOM   3846  C CG  . GLU B 1 46  ? 175.583 155.527 223.085 1.00 100.42 ? 67  GLU B CG  1 
ATOM   3847  C CD  . GLU B 1 46  ? 175.226 156.904 223.611 1.00 100.42 ? 67  GLU B CD  1 
ATOM   3848  O OE1 . GLU B 1 46  ? 175.588 157.905 222.959 1.00 100.42 ? 67  GLU B OE1 1 
ATOM   3849  O OE2 . GLU B 1 46  ? 174.580 156.984 224.677 1.00 100.42 ? 67  GLU B OE2 1 
ATOM   3850  N N   . MET B 1 47  ? 178.375 154.287 220.214 1.00 109.00 ? 68  MET B N   1 
ATOM   3851  C CA  . MET B 1 47  ? 179.178 153.743 219.129 1.00 109.00 ? 68  MET B CA  1 
ATOM   3852  C C   . MET B 1 47  ? 178.566 154.280 217.834 1.00 109.00 ? 68  MET B C   1 
ATOM   3853  O O   . MET B 1 47  ? 178.269 153.538 216.892 1.00 109.00 ? 68  MET B O   1 
ATOM   3854  C CB  . MET B 1 47  ? 179.218 152.207 219.221 1.00 109.00 ? 68  MET B CB  1 
ATOM   3855  C CG  . MET B 1 47  ? 180.214 151.482 218.301 1.00 109.00 ? 68  MET B CG  1 
ATOM   3856  S SD  . MET B 1 47  ? 181.926 151.857 218.726 1.00 109.00 ? 68  MET B SD  1 
ATOM   3857  C CE  . MET B 1 47  ? 182.743 151.525 217.168 1.00 109.00 ? 68  MET B CE  1 
ATOM   3858  N N   . SER B 1 48  ? 178.322 155.591 217.807 1.00 86.70  ? 69  SER B N   1 
ATOM   3859  C CA  . SER B 1 48  ? 177.755 156.242 216.632 1.00 86.70  ? 69  SER B CA  1 
ATOM   3860  C C   . SER B 1 48  ? 178.752 156.378 215.490 1.00 86.70  ? 69  SER B C   1 
ATOM   3861  O O   . SER B 1 48  ? 178.338 156.650 214.358 1.00 86.70  ? 69  SER B O   1 
ATOM   3862  C CB  . SER B 1 48  ? 177.216 157.624 217.006 1.00 86.70  ? 69  SER B CB  1 
ATOM   3863  O OG  . SER B 1 48  ? 176.151 157.522 217.934 1.00 86.70  ? 69  SER B OG  1 
ATOM   3864  N N   . ILE B 1 49  ? 180.046 156.198 215.757 1.00 64.90  ? 70  ILE B N   1 
ATOM   3865  C CA  . ILE B 1 49  ? 181.059 156.299 214.713 1.00 64.90  ? 70  ILE B CA  1 
ATOM   3866  C C   . ILE B 1 49  ? 181.068 155.054 213.826 1.00 64.90  ? 70  ILE B C   1 
ATOM   3867  O O   . ILE B 1 49  ? 181.556 155.115 212.690 1.00 64.90  ? 70  ILE B O   1 
ATOM   3868  C CB  . ILE B 1 49  ? 182.429 156.557 215.371 1.00 64.90  ? 70  ILE B CB  1 
ATOM   3869  C CG1 . ILE B 1 49  ? 182.295 157.593 216.490 1.00 64.90  ? 70  ILE B CG1 1 
ATOM   3870  C CG2 . ILE B 1 49  ? 183.459 157.088 214.371 1.00 64.90  ? 70  ILE B CG2 1 
ATOM   3871  C CD1 . ILE B 1 49  ? 181.902 158.991 216.017 1.00 64.90  ? 70  ILE B CD1 1 
ATOM   3872  N N   . ASP B 1 50  ? 180.499 153.939 214.303 1.00 62.87  ? 71  ASP B N   1 
ATOM   3873  C CA  . ASP B 1 50  ? 180.552 152.673 213.572 1.00 62.87  ? 71  ASP B CA  1 
ATOM   3874  C C   . ASP B 1 50  ? 179.725 152.720 212.290 1.00 62.87  ? 71  ASP B C   1 
ATOM   3875  O O   . ASP B 1 50  ? 180.122 152.142 211.269 1.00 62.87  ? 71  ASP B O   1 
ATOM   3876  C CB  . ASP B 1 50  ? 180.073 151.536 214.473 1.00 62.87  ? 71  ASP B CB  1 
ATOM   3877  C CG  . ASP B 1 50  ? 180.596 150.183 214.036 1.00 62.87  ? 71  ASP B CG  1 
ATOM   3878  O OD1 . ASP B 1 50  ? 181.403 150.129 213.085 1.00 62.87  ? 71  ASP B OD1 1 
ATOM   3879  O OD2 . ASP B 1 50  ? 180.199 149.169 214.649 1.00 62.87  ? 71  ASP B OD2 1 
ATOM   3880  N N   . GLY B 1 51  ? 178.582 153.410 212.323 1.00 40.68  ? 72  GLY B N   1 
ATOM   3881  C CA  . GLY B 1 51  ? 177.798 153.588 211.111 1.00 40.68  ? 72  GLY B CA  1 
ATOM   3882  C C   . GLY B 1 51  ? 178.508 154.441 210.077 1.00 40.68  ? 72  GLY B C   1 
ATOM   3883  O O   . GLY B 1 51  ? 178.456 154.150 208.878 1.00 40.68  ? 72  GLY B O   1 
ATOM   3884  N N   . TYR B 1 52  ? 179.209 155.484 210.531 1.00 29.77  ? 73  TYR B N   1 
ATOM   3885  C CA  . TYR B 1 52  ? 180.001 156.312 209.627 1.00 29.77  ? 73  TYR B CA  1 
ATOM   3886  C C   . TYR B 1 52  ? 181.176 155.533 209.044 1.00 29.77  ? 73  TYR B C   1 
ATOM   3887  O O   . TYR B 1 52  ? 181.519 155.710 207.869 1.00 29.77  ? 73  TYR B O   1 
ATOM   3888  C CB  . TYR B 1 52  ? 180.491 157.558 210.362 1.00 29.77  ? 73  TYR B CB  1 
ATOM   3889  C CG  . TYR B 1 52  ? 181.144 158.585 209.468 1.00 29.77  ? 73  TYR B CG  1 
ATOM   3890  C CD1 . TYR B 1 52  ? 180.440 159.176 208.426 1.00 29.77  ? 73  TYR B CD1 1 
ATOM   3891  C CD2 . TYR B 1 52  ? 182.466 158.965 209.667 1.00 29.77  ? 73  TYR B CD2 1 
ATOM   3892  C CE1 . TYR B 1 52  ? 181.035 160.117 207.606 1.00 29.77  ? 73  TYR B CE1 1 
ATOM   3893  C CE2 . TYR B 1 52  ? 183.070 159.905 208.852 1.00 29.77  ? 73  TYR B CE2 1 
ATOM   3894  C CZ  . TYR B 1 52  ? 182.350 160.477 207.824 1.00 29.77  ? 73  TYR B CZ  1 
ATOM   3895  O OH  . TYR B 1 52  ? 182.946 161.412 207.011 1.00 29.77  ? 73  TYR B OH  1 
ATOM   3896  N N   . LEU B 1 53  ? 181.797 154.663 209.849 1.00 31.77  ? 74  LEU B N   1 
ATOM   3897  C CA  . LEU B 1 53  ? 182.886 153.819 209.360 1.00 31.77  ? 74  LEU B CA  1 
ATOM   3898  C C   . LEU B 1 53  ? 182.398 152.821 208.318 1.00 31.77  ? 74  LEU B C   1 
ATOM   3899  O O   . LEU B 1 53  ? 183.061 152.611 207.295 1.00 31.77  ? 74  LEU B O   1 
ATOM   3900  C CB  . LEU B 1 53  ? 183.550 153.085 210.525 1.00 31.77  ? 74  LEU B CB  1 
ATOM   3901  C CG  . LEU B 1 53  ? 184.418 153.914 211.470 1.00 31.77  ? 74  LEU B CG  1 
ATOM   3902  C CD1 . LEU B 1 53  ? 184.866 153.078 212.656 1.00 31.77  ? 74  LEU B CD1 1 
ATOM   3903  C CD2 . LEU B 1 53  ? 185.616 154.471 210.727 1.00 31.77  ? 74  LEU B CD2 1 
ATOM   3904  N N   . ASN B 1 54  ? 181.233 152.207 208.554 1.00 31.46  ? 75  ASN B N   1 
ATOM   3905  C CA  . ASN B 1 54  ? 180.663 151.297 207.564 1.00 31.46  ? 75  ASN B CA  1 
ATOM   3906  C C   . ASN B 1 54  ? 180.186 152.039 206.321 1.00 31.46  ? 75  ASN B C   1 
ATOM   3907  O O   . ASN B 1 54  ? 180.114 151.446 205.239 1.00 31.46  ? 75  ASN B O   1 
ATOM   3908  C CB  . ASN B 1 54  ? 179.514 150.501 208.180 1.00 31.46  ? 75  ASN B CB  1 
ATOM   3909  C CG  . ASN B 1 54  ? 179.980 149.211 208.821 1.00 31.46  ? 75  ASN B CG  1 
ATOM   3910  O OD1 . ASN B 1 54  ? 181.150 148.843 208.723 1.00 31.46  ? 75  ASN B OD1 1 
ATOM   3911  N ND2 . ASN B 1 54  ? 179.064 148.516 209.485 1.00 31.46  ? 75  ASN B ND2 1 
ATOM   3912  N N   . LEU B 1 55  ? 179.849 153.324 206.454 1.00 22.28  ? 76  LEU B N   1 
ATOM   3913  C CA  . LEU B 1 55  ? 179.485 154.110 205.281 1.00 22.28  ? 76  LEU B CA  1 
ATOM   3914  C C   . LEU B 1 55  ? 180.710 154.474 204.447 1.00 22.28  ? 76  LEU B C   1 
ATOM   3915  O O   . LEU B 1 55  ? 180.658 154.432 203.212 1.00 22.28  ? 76  LEU B O   1 
ATOM   3916  C CB  . LEU B 1 55  ? 178.732 155.368 205.708 1.00 22.28  ? 76  LEU B CB  1 
ATOM   3917  C CG  . LEU B 1 55  ? 177.229 155.199 205.940 1.00 22.28  ? 76  LEU B CG  1 
ATOM   3918  C CD1 . LEU B 1 55  ? 176.615 156.488 206.465 1.00 22.28  ? 76  LEU B CD1 1 
ATOM   3919  C CD2 . LEU B 1 55  ? 176.526 154.734 204.676 1.00 22.28  ? 76  LEU B CD2 1 
ATOM   3920  N N   . ILE B 1 56  ? 181.824 154.835 205.098 1.00 20.17  ? 77  ILE B N   1 
ATOM   3921  C CA  . ILE B 1 56  ? 183.008 155.278 204.359 1.00 20.17  ? 77  ILE B CA  1 
ATOM   3922  C C   . ILE B 1 56  ? 183.934 154.140 203.949 1.00 20.17  ? 77  ILE B C   1 
ATOM   3923  O O   . ILE B 1 56  ? 184.864 154.371 203.156 1.00 20.17  ? 77  ILE B O   1 
ATOM   3924  C CB  . ILE B 1 56  ? 183.840 156.307 205.151 1.00 20.17  ? 77  ILE B CB  1 
ATOM   3925  C CG1 . ILE B 1 56  ? 184.462 155.659 206.389 1.00 20.17  ? 77  ILE B CG1 1 
ATOM   3926  C CG2 . ILE B 1 56  ? 182.998 157.521 205.509 1.00 20.17  ? 77  ILE B CG2 1 
ATOM   3927  C CD1 . ILE B 1 56  ? 185.545 156.490 207.028 1.00 20.17  ? 77  ILE B CD1 1 
ATOM   3928  N N   . ASN B 1 57  ? 183.728 152.924 204.465 1.00 21.92  ? 78  ASN B N   1 
ATOM   3929  C CA  . ASN B 1 57  ? 184.523 151.794 203.998 1.00 21.92  ? 78  ASN B CA  1 
ATOM   3930  C C   . ASN B 1 57  ? 184.126 151.344 202.599 1.00 21.92  ? 78  ASN B C   1 
ATOM   3931  O O   . ASN B 1 57  ? 184.914 150.664 201.936 1.00 21.92  ? 78  ASN B O   1 
ATOM   3932  C CB  . ASN B 1 57  ? 184.411 150.621 204.971 1.00 21.92  ? 78  ASN B CB  1 
ATOM   3933  C CG  . ASN B 1 57  ? 185.362 150.745 206.143 1.00 21.92  ? 78  ASN B CG  1 
ATOM   3934  O OD1 . ASN B 1 57  ? 186.503 151.177 205.987 1.00 21.92  ? 78  ASN B OD1 1 
ATOM   3935  N ND2 . ASN B 1 57  ? 184.897 150.364 207.326 1.00 21.92  ? 78  ASN B ND2 1 
ATOM   3936  N N   . ALA B 1 58  ? 182.928 151.703 202.138 1.00 20.99  ? 79  ALA B N   1 
ATOM   3937  C CA  . ALA B 1 58  ? 182.543 151.447 200.758 1.00 20.99  ? 79  ALA B CA  1 
ATOM   3938  C C   . ALA B 1 58  ? 183.089 152.491 199.795 1.00 20.99  ? 79  ALA B C   1 
ATOM   3939  O O   . ALA B 1 58  ? 182.950 152.322 198.579 1.00 20.99  ? 79  ALA B O   1 
ATOM   3940  C CB  . ALA B 1 58  ? 181.019 151.385 200.637 1.00 20.99  ? 79  ALA B CB  1 
ATOM   3941  N N   . VAL B 1 59  ? 183.696 153.557 200.306 1.00 22.53  ? 80  VAL B N   1 
ATOM   3942  C CA  . VAL B 1 59  ? 184.294 154.592 199.477 1.00 22.53  ? 80  VAL B CA  1 
ATOM   3943  C C   . VAL B 1 59  ? 185.816 154.501 199.480 1.00 22.53  ? 80  VAL B C   1 
ATOM   3944  O O   . VAL B 1 59  ? 186.448 154.610 198.429 1.00 22.53  ? 80  VAL B O   1 
ATOM   3945  C CB  . VAL B 1 59  ? 183.817 155.983 199.950 1.00 22.53  ? 80  VAL B CB  1 
ATOM   3946  C CG1 . VAL B 1 59  ? 184.385 157.088 199.071 1.00 22.53  ? 80  VAL B CG1 1 
ATOM   3947  C CG2 . VAL B 1 59  ? 182.300 156.043 199.974 1.00 22.53  ? 80  VAL B CG2 1 
ATOM   3948  N N   . ILE B 1 60  ? 186.411 154.281 200.655 1.00 21.13  ? 81  ILE B N   1 
ATOM   3949  C CA  . ILE B 1 60  ? 187.867 154.318 200.781 1.00 21.13  ? 81  ILE B CA  1 
ATOM   3950  C C   . ILE B 1 60  ? 188.499 153.066 200.170 1.00 21.13  ? 81  ILE B C   1 
ATOM   3951  O O   . ILE B 1 60  ? 189.486 153.151 199.428 1.00 21.13  ? 81  ILE B O   1 
ATOM   3952  C CB  . ILE B 1 60  ? 188.256 154.507 202.260 1.00 21.13  ? 81  ILE B CB  1 
ATOM   3953  C CG1 . ILE B 1 60  ? 188.049 155.963 202.670 1.00 21.13  ? 81  ILE B CG1 1 
ATOM   3954  C CG2 . ILE B 1 60  ? 189.697 154.124 202.522 1.00 21.13  ? 81  ILE B CG2 1 
ATOM   3955  C CD1 . ILE B 1 60  ? 188.197 156.203 204.152 1.00 21.13  ? 81  ILE B CD1 1 
ATOM   3956  N N   . ILE B 1 61  ? 187.922 151.892 200.458 1.00 24.35  ? 82  ILE B N   1 
ATOM   3957  C CA  . ILE B 1 61  ? 188.514 150.623 200.005 1.00 24.35  ? 82  ILE B CA  1 
ATOM   3958  C C   . ILE B 1 61  ? 188.524 150.438 198.483 1.00 24.35  ? 82  ILE B C   1 
ATOM   3959  O O   . ILE B 1 61  ? 189.577 150.053 197.944 1.00 24.35  ? 82  ILE B O   1 
ATOM   3960  C CB  . ILE B 1 61  ? 187.865 149.445 200.755 1.00 24.35  ? 82  ILE B CB  1 
ATOM   3961  C CG1 . ILE B 1 61  ? 188.100 149.583 202.258 1.00 24.35  ? 82  ILE B CG1 1 
ATOM   3962  C CG2 . ILE B 1 61  ? 188.401 148.105 200.275 1.00 24.35  ? 82  ILE B CG2 1 
ATOM   3963  C CD1 . ILE B 1 61  ? 187.323 148.585 203.085 1.00 24.35  ? 82  ILE B CD1 1 
ATOM   3964  N N   . PRO B 1 62  ? 187.424 150.684 197.728 1.00 20.59  ? 83  PRO B N   1 
ATOM   3965  C CA  . PRO B 1 62  ? 187.538 150.549 196.260 1.00 20.59  ? 83  PRO B CA  1 
ATOM   3966  C C   . PRO B 1 62  ? 188.424 151.594 195.600 1.00 20.59  ? 83  PRO B C   1 
ATOM   3967  O O   . PRO B 1 62  ? 188.858 151.376 194.462 1.00 20.59  ? 83  PRO B O   1 
ATOM   3968  C CB  . PRO B 1 62  ? 186.087 150.675 195.775 1.00 20.59  ? 83  PRO B CB  1 
ATOM   3969  C CG  . PRO B 1 62  ? 185.282 150.296 196.931 1.00 20.59  ? 83  PRO B CG  1 
ATOM   3970  C CD  . PRO B 1 62  ? 186.003 150.932 198.062 1.00 20.59  ? 83  PRO B CD  1 
ATOM   3971  N N   . ILE B 1 63  ? 188.698 152.716 196.264 1.00 23.53  ? 84  ILE B N   1 
ATOM   3972  C CA  . ILE B 1 63  ? 189.716 153.637 195.770 1.00 23.53  ? 84  ILE B CA  1 
ATOM   3973  C C   . ILE B 1 63  ? 191.102 153.022 195.933 1.00 23.53  ? 84  ILE B C   1 
ATOM   3974  O O   . ILE B 1 63  ? 191.914 153.018 194.998 1.00 23.53  ? 84  ILE B O   1 
ATOM   3975  C CB  . ILE B 1 63  ? 189.597 154.994 196.490 1.00 23.53  ? 84  ILE B CB  1 
ATOM   3976  C CG1 . ILE B 1 63  ? 188.380 155.764 195.977 1.00 23.53  ? 84  ILE B CG1 1 
ATOM   3977  C CG2 . ILE B 1 63  ? 190.843 155.836 196.296 1.00 23.53  ? 84  ILE B CG2 1 
ATOM   3978  C CD1 . ILE B 1 63  ? 188.145 157.079 196.689 1.00 23.53  ? 84  ILE B CD1 1 
ATOM   3979  N N   . SER B 1 64  ? 191.369 152.442 197.110 1.00 18.56  ? 85  SER B N   1 
ATOM   3980  C CA  . SER B 1 64  ? 192.703 151.939 197.429 1.00 18.56  ? 85  SER B CA  1 
ATOM   3981  C C   . SER B 1 64  ? 193.048 150.689 196.630 1.00 18.56  ? 85  SER B C   1 
ATOM   3982  O O   . SER B 1 64  ? 194.211 150.499 196.251 1.00 18.56  ? 85  SER B O   1 
ATOM   3983  C CB  . SER B 1 64  ? 192.813 151.654 198.925 1.00 18.56  ? 85  SER B CB  1 
ATOM   3984  O OG  . SER B 1 64  ? 193.978 150.899 199.207 1.00 18.56  ? 85  SER B OG  1 
ATOM   3985  N N   . GLN B 1 65  ? 192.057 149.825 196.372 1.00 24.38  ? 86  GLN B N   1 
ATOM   3986  C CA  . GLN B 1 65  ? 192.301 148.608 195.597 1.00 24.38  ? 86  GLN B CA  1 
ATOM   3987  C C   . GLN B 1 65  ? 192.684 148.932 194.156 1.00 24.38  ? 86  GLN B C   1 
ATOM   3988  O O   . GLN B 1 65  ? 193.652 148.376 193.619 1.00 24.38  ? 86  GLN B O   1 
ATOM   3989  C CB  . GLN B 1 65  ? 191.066 147.708 195.630 1.00 24.38  ? 86  GLN B CB  1 
ATOM   3990  C CG  . GLN B 1 65  ? 190.795 147.065 196.977 1.00 24.38  ? 86  GLN B CG  1 
ATOM   3991  C CD  . GLN B 1 65  ? 191.921 146.160 197.425 1.00 24.38  ? 86  GLN B CD  1 
ATOM   3992  O OE1 . GLN B 1 65  ? 192.649 146.474 198.366 1.00 24.38  ? 86  GLN B OE1 1 
ATOM   3993  N NE2 . GLN B 1 65  ? 192.069 145.025 196.753 1.00 24.38  ? 86  GLN B NE2 1 
ATOM   3994  N N   . SER B 1 66  ? 191.950 149.856 193.527 1.00 24.91  ? 87  SER B N   1 
ATOM   3995  C CA  . SER B 1 66  ? 192.297 150.301 192.182 1.00 24.91  ? 87  SER B CA  1 
ATOM   3996  C C   . SER B 1 66  ? 193.612 151.068 192.167 1.00 24.91  ? 87  SER B C   1 
ATOM   3997  O O   . SER B 1 66  ? 194.363 150.977 191.190 1.00 24.91  ? 87  SER B O   1 
ATOM   3998  C CB  . SER B 1 66  ? 191.176 151.163 191.605 1.00 24.91  ? 87  SER B CB  1 
ATOM   3999  O OG  . SER B 1 66  ? 191.602 151.825 190.427 1.00 24.91  ? 87  SER B OG  1 
ATOM   4000  N N   . LEU B 1 67  ? 193.918 151.795 193.249 1.00 28.28  ? 88  LEU B N   1 
ATOM   4001  C CA  . LEU B 1 67  ? 195.177 152.527 193.335 1.00 28.28  ? 88  LEU B CA  1 
ATOM   4002  C C   . LEU B 1 67  ? 196.376 151.584 193.384 1.00 28.28  ? 88  LEU B C   1 
ATOM   4003  O O   . LEU B 1 67  ? 197.360 151.783 192.662 1.00 28.28  ? 88  LEU B O   1 
ATOM   4004  C CB  . LEU B 1 67  ? 195.157 153.433 194.564 1.00 28.28  ? 88  LEU B CB  1 
ATOM   4005  C CG  . LEU B 1 67  ? 196.058 154.661 194.532 1.00 28.28  ? 88  LEU B CG  1 
ATOM   4006  C CD1 . LEU B 1 67  ? 195.706 155.505 193.330 1.00 28.28  ? 88  LEU B CD1 1 
ATOM   4007  C CD2 . LEU B 1 67  ? 195.892 155.459 195.805 1.00 28.28  ? 88  LEU B CD2 1 
ATOM   4008  N N   . GLU B 1 68  ? 196.304 150.530 194.199 1.00 34.03  ? 89  GLU B N   1 
ATOM   4009  C CA  . GLU B 1 68  ? 197.428 149.598 194.267 1.00 34.03  ? 89  GLU B CA  1 
ATOM   4010  C C   . GLU B 1 68  ? 197.496 148.689 193.041 1.00 34.03  ? 89  GLU B C   1 
ATOM   4011  O O   . GLU B 1 68  ? 198.596 148.272 192.645 1.00 34.03  ? 89  GLU B O   1 
ATOM   4012  C CB  . GLU B 1 68  ? 197.370 148.793 195.569 1.00 34.03  ? 89  GLU B CB  1 
ATOM   4013  C CG  . GLU B 1 68  ? 196.152 147.914 195.740 1.00 34.03  ? 89  GLU B CG  1 
ATOM   4014  C CD  . GLU B 1 68  ? 196.391 146.490 195.317 1.00 34.03  ? 89  GLU B CD  1 
ATOM   4015  O OE1 . GLU B 1 68  ? 197.570 146.090 195.222 1.00 34.03  ? 89  GLU B OE1 1 
ATOM   4016  O OE2 . GLU B 1 68  ? 195.396 145.777 195.078 1.00 34.03  ? 89  GLU B OE2 1 
ATOM   4017  N N   . LEU B 1 69  ? 196.350 148.393 192.409 1.00 33.58  ? 90  LEU B N   1 
ATOM   4018  C CA  . LEU B 1 69  ? 196.380 147.659 191.146 1.00 33.58  ? 90  LEU B CA  1 
ATOM   4019  C C   . LEU B 1 69  ? 196.974 148.510 190.031 1.00 33.58  ? 90  LEU B C   1 
ATOM   4020  O O   . LEU B 1 69  ? 197.594 147.974 189.106 1.00 33.58  ? 90  LEU B O   1 
ATOM   4021  C CB  . LEU B 1 69  ? 194.968 147.176 190.790 1.00 33.58  ? 90  LEU B CB  1 
ATOM   4022  C CG  . LEU B 1 69  ? 194.692 146.197 189.637 1.00 33.58  ? 90  LEU B CG  1 
ATOM   4023  C CD1 . LEU B 1 69  ? 193.468 145.371 189.983 1.00 33.58  ? 90  LEU B CD1 1 
ATOM   4024  C CD2 . LEU B 1 69  ? 194.453 146.886 188.294 1.00 33.58  ? 90  LEU B CD2 1 
ATOM   4025  N N   . MET B 1 70  ? 196.792 149.829 190.099 1.00 30.76  ? 91  MET B N   1 
ATOM   4026  C CA  . MET B 1 70  ? 197.508 150.729 189.208 1.00 30.76  ? 91  MET B CA  1 
ATOM   4027  C C   . MET B 1 70  ? 198.982 150.839 189.577 1.00 30.76  ? 91  MET B C   1 
ATOM   4028  O O   . MET B 1 70  ? 199.812 151.099 188.700 1.00 30.76  ? 91  MET B O   1 
ATOM   4029  C CB  . MET B 1 70  ? 196.849 152.109 189.243 1.00 30.76  ? 91  MET B CB  1 
ATOM   4030  C CG  . MET B 1 70  ? 197.121 152.966 188.030 1.00 30.76  ? 91  MET B CG  1 
ATOM   4031  S SD  . MET B 1 70  ? 195.977 152.657 186.674 1.00 30.76  ? 91  MET B SD  1 
ATOM   4032  C CE  . MET B 1 70  ? 194.413 152.719 187.541 1.00 30.76  ? 91  MET B CE  1 
ATOM   4033  N N   . ARG B 1 71  ? 199.320 150.643 190.853 1.00 32.75  ? 92  ARG B N   1 
ATOM   4034  C CA  . ARG B 1 71  ? 200.702 150.789 191.302 1.00 32.75  ? 92  ARG B CA  1 
ATOM   4035  C C   . ARG B 1 71  ? 201.572 149.604 190.882 1.00 32.75  ? 92  ARG B C   1 
ATOM   4036  O O   . ARG B 1 71  ? 202.751 149.785 190.554 1.00 32.75  ? 92  ARG B O   1 
ATOM   4037  C CB  . ARG B 1 71  ? 200.743 150.989 192.822 1.00 32.75  ? 92  ARG B CB  1 
ATOM   4038  C CG  . ARG B 1 71  ? 202.137 151.238 193.396 1.00 32.75  ? 92  ARG B CG  1 
ATOM   4039  C CD  . ARG B 1 71  ? 202.092 151.627 194.864 1.00 32.75  ? 92  ARG B CD  1 
ATOM   4040  N NE  . ARG B 1 71  ? 201.094 152.655 195.130 1.00 32.75  ? 92  ARG B NE  1 
ATOM   4041  C CZ  . ARG B 1 71  ? 201.323 153.958 195.039 1.00 32.75  ? 92  ARG B CZ  1 
ATOM   4042  N NH1 . ARG B 1 71  ? 202.514 154.428 194.709 1.00 32.75  ? 92  ARG B NH1 1 
ATOM   4043  N NH2 . ARG B 1 71  ? 200.334 154.810 195.291 1.00 32.75  ? 92  ARG B NH2 1 
ATOM   4044  N N   . ASN B 1 72  ? 201.020 148.378 190.897 1.00 55.42  ? 93  ASN B N   1 
ATOM   4045  C CA  . ASN B 1 72  ? 201.797 147.236 190.400 1.00 55.42  ? 93  ASN B CA  1 
ATOM   4046  C C   . ASN B 1 72  ? 202.215 147.290 188.935 1.00 55.42  ? 93  ASN B C   1 
ATOM   4047  O O   . ASN B 1 72  ? 203.269 146.754 188.579 1.00 55.42  ? 93  ASN B O   1 
ATOM   4048  C CB  . ASN B 1 72  ? 201.098 145.881 190.573 1.00 55.42  ? 93  ASN B CB  1 
ATOM   4049  C CG  . ASN B 1 72  ? 201.248 145.294 191.954 1.00 55.42  ? 93  ASN B CG  1 
ATOM   4050  O OD1 . ASN B 1 72  ? 202.247 145.538 192.629 1.00 55.42  ? 93  ASN B OD1 1 
ATOM   4051  N ND2 . ASN B 1 72  ? 200.319 144.402 192.322 1.00 55.42  ? 93  ASN B ND2 1 
ATOM   4052  N N   . ASN B 1 73  ? 201.420 147.915 188.077 1.00 48.00  ? 94  ASN B N   1 
ATOM   4053  C CA  . ASN B 1 73  ? 201.640 147.789 186.641 1.00 48.00  ? 94  ASN B CA  1 
ATOM   4054  C C   . ASN B 1 73  ? 202.755 148.687 186.101 1.00 48.00  ? 94  ASN B C   1 
ATOM   4055  O O   . ASN B 1 73  ? 202.924 148.757 184.878 1.00 48.00  ? 94  ASN B O   1 
ATOM   4056  C CB  . ASN B 1 73  ? 200.336 148.059 185.895 1.00 48.00  ? 94  ASN B CB  1 
ATOM   4057  C CG  . ASN B 1 73  ? 199.245 147.083 186.274 1.00 48.00  ? 94  ASN B CG  1 
ATOM   4058  O OD1 . ASN B 1 73  ? 199.441 146.219 187.128 1.00 48.00  ? 94  ASN B OD1 1 
ATOM   4059  N ND2 . ASN B 1 73  ? 198.089 147.211 185.636 1.00 48.00  ? 94  ASN B ND2 1 
ATOM   4060  N N   . VAL B 1 74  ? 203.510 149.368 186.959 1.00 49.33  ? 95  VAL B N   1 
ATOM   4061  C CA  . VAL B 1 74  ? 204.723 150.075 186.565 1.00 49.33  ? 95  VAL B CA  1 
ATOM   4062  C C   . VAL B 1 74  ? 205.889 149.496 187.363 1.00 49.33  ? 95  VAL B C   1 
ATOM   4063  O O   . VAL B 1 74  ? 205.773 149.265 188.573 1.00 49.33  ? 95  VAL B O   1 
ATOM   4064  C CB  . VAL B 1 74  ? 204.579 151.603 186.744 1.00 49.33  ? 95  VAL B CB  1 
ATOM   4065  C CG1 . VAL B 1 74  ? 204.122 151.987 188.155 1.00 49.33  ? 95  VAL B CG1 1 
ATOM   4066  C CG2 . VAL B 1 74  ? 205.865 152.334 186.360 1.00 49.33  ? 95  VAL B CG2 1 
ATOM   4067  N N   . LYS B 1 75  ? 206.984 149.190 186.671 1.00 57.67  ? 96  LYS B N   1 
ATOM   4068  C CA  . LYS B 1 75  ? 208.154 148.601 187.302 1.00 57.67  ? 96  LYS B CA  1 
ATOM   4069  C C   . LYS B 1 75  ? 209.417 149.245 186.754 1.00 57.67  ? 96  LYS B C   1 
ATOM   4070  O O   . LYS B 1 75  ? 209.544 149.456 185.544 1.00 57.67  ? 96  LYS B O   1 
ATOM   4071  C CB  . LYS B 1 75  ? 208.193 147.075 187.083 1.00 57.67  ? 96  LYS B CB  1 
ATOM   4072  C CG  . LYS B 1 75  ? 209.319 146.335 187.815 1.00 57.67  ? 96  LYS B CG  1 
ATOM   4073  C CD  . LYS B 1 75  ? 209.309 146.539 189.334 1.00 57.67  ? 96  LYS B CD  1 
ATOM   4074  C CE  . LYS B 1 75  ? 207.986 146.122 189.982 1.00 57.67  ? 96  LYS B CE  1 
ATOM   4075  N NZ  . LYS B 1 75  ? 207.826 144.643 190.025 1.00 57.67  ? 96  LYS B NZ  1 
ATOM   4076  N N   . ASP B 1 76  ? 210.349 149.549 187.651 1.00 62.04  ? 97  ASP B N   1 
ATOM   4077  C CA  . ASP B 1 76  ? 211.633 150.116 187.274 1.00 62.04  ? 97  ASP B CA  1 
ATOM   4078  C C   . ASP B 1 76  ? 212.618 148.968 187.040 1.00 62.04  ? 97  ASP B C   1 
ATOM   4079  O O   . ASP B 1 76  ? 212.232 147.799 186.961 1.00 62.04  ? 97  ASP B O   1 
ATOM   4080  C CB  . ASP B 1 76  ? 212.097 151.105 188.343 1.00 62.04  ? 97  ASP B CB  1 
ATOM   4081  C CG  . ASP B 1 76  ? 213.012 152.182 187.787 1.00 62.04  ? 97  ASP B CG  1 
ATOM   4082  O OD1 . ASP B 1 76  ? 213.287 152.155 186.569 1.00 62.04  ? 97  ASP B OD1 1 
ATOM   4083  O OD2 . ASP B 1 76  ? 213.449 153.055 188.566 1.00 62.04  ? 97  ASP B OD2 1 
ATOM   4084  N N   . GLY B 1 77  ? 213.905 149.285 186.925 1.00 79.59  ? 98  GLY B N   1 
ATOM   4085  C CA  . GLY B 1 77  ? 214.895 148.297 186.547 1.00 79.59  ? 98  GLY B CA  1 
ATOM   4086  C C   . GLY B 1 77  ? 215.434 148.595 185.165 1.00 79.59  ? 98  GLY B C   1 
ATOM   4087  O O   . GLY B 1 77  ? 214.659 148.932 184.268 1.00 79.59  ? 98  GLY B O   1 
ATOM   4088  N N   . THR B 1 78  ? 216.753 148.506 184.988 1.00 94.34  ? 99  THR B N   1 
ATOM   4089  C CA  . THR B 1 78  ? 217.415 148.921 183.754 1.00 94.34  ? 99  THR B CA  1 
ATOM   4090  C C   . THR B 1 78  ? 217.048 148.065 182.539 1.00 94.34  ? 99  THR B C   1 
ATOM   4091  O O   . THR B 1 78  ? 217.116 146.829 182.585 1.00 94.34  ? 99  THR B O   1 
ATOM   4092  C CB  . THR B 1 78  ? 218.940 148.969 183.969 1.00 94.34  ? 99  THR B CB  1 
ATOM   4093  O OG1 . THR B 1 78  ? 219.597 149.364 182.756 1.00 94.34  ? 99  THR B OG1 1 
ATOM   4094  C CG2 . THR B 1 78  ? 219.527 147.659 184.525 1.00 94.34  ? 99  THR B CG2 1 
ATOM   4095  N N   . PRO B 1 79  ? 216.573 148.687 181.456 1.00 90.10  ? 100 PRO B N   1 
ATOM   4096  C CA  . PRO B 1 79  ? 216.518 147.977 180.175 1.00 90.10  ? 100 PRO B CA  1 
ATOM   4097  C C   . PRO B 1 79  ? 217.888 148.001 179.528 1.00 90.10  ? 100 PRO B C   1 
ATOM   4098  O O   . PRO B 1 79  ? 218.291 149.067 179.053 1.00 90.10  ? 100 PRO B O   1 
ATOM   4099  C CB  . PRO B 1 79  ? 215.498 148.785 179.359 1.00 90.10  ? 100 PRO B CB  1 
ATOM   4100  C CG  . PRO B 1 79  ? 214.814 149.683 180.354 1.00 90.10  ? 100 PRO B CG  1 
ATOM   4101  C CD  . PRO B 1 79  ? 215.858 149.969 181.386 1.00 90.10  ? 100 PRO B CD  1 
ATOM   4102  N N   . ASN B 1 80  ? 218.584 146.849 179.541 1.00 96.88  ? 101 ASN B N   1 
ATOM   4103  C CA  . ASN B 1 80  ? 219.959 146.567 179.097 1.00 96.88  ? 101 ASN B CA  1 
ATOM   4104  C C   . ASN B 1 80  ? 220.935 147.751 179.199 1.00 96.88  ? 101 ASN B C   1 
ATOM   4105  O O   . ASN B 1 80  ? 221.203 148.216 180.312 1.00 96.88  ? 101 ASN B O   1 
ATOM   4106  C CB  . ASN B 1 80  ? 219.944 145.862 177.709 1.00 96.88  ? 101 ASN B CB  1 
ATOM   4107  C CG  . ASN B 1 80  ? 219.324 146.677 176.561 1.00 96.88  ? 101 ASN B CG  1 
ATOM   4108  O OD1 . ASN B 1 80  ? 219.089 147.874 176.658 1.00 96.88  ? 101 ASN B OD1 1 
ATOM   4109  N ND2 . ASN B 1 80  ? 219.072 145.994 175.451 1.00 96.88  ? 101 ASN B ND2 1 
ATOM   4110  N N   . GLU B 1 81  ? 221.483 148.235 178.079 1.00 103.20 ? 102 GLU B N   1 
ATOM   4111  C CA  . GLU B 1 81  ? 222.456 149.324 178.116 1.00 103.20 ? 102 GLU B CA  1 
ATOM   4112  C C   . GLU B 1 81  ? 221.841 150.659 178.536 1.00 103.20 ? 102 GLU B C   1 
ATOM   4113  O O   . GLU B 1 81  ? 222.561 151.533 179.032 1.00 103.20 ? 102 GLU B O   1 
ATOM   4114  C CB  . GLU B 1 81  ? 223.147 149.439 176.752 1.00 103.20 ? 102 GLU B CB  1 
ATOM   4115  C CG  . GLU B 1 81  ? 222.215 149.606 175.546 1.00 103.20 ? 102 GLU B CG  1 
ATOM   4116  C CD  . GLU B 1 81  ? 221.848 151.050 175.250 1.00 103.20 ? 102 GLU B CD  1 
ATOM   4117  O OE1 . GLU B 1 81  ? 222.557 151.958 175.732 1.00 103.20 ? 102 GLU B OE1 1 
ATOM   4118  O OE2 . GLU B 1 81  ? 220.851 151.273 174.531 1.00 103.20 ? 102 GLU B OE2 1 
ATOM   4119  N N   . ASN B 1 82  ? 220.534 150.845 178.340 1.00 101.36 ? 103 ASN B N   1 
ATOM   4120  C CA  . ASN B 1 82  ? 219.889 152.088 178.753 1.00 101.36 ? 103 ASN B CA  1 
ATOM   4121  C C   . ASN B 1 82  ? 219.781 152.156 180.273 1.00 101.36 ? 103 ASN B C   1 
ATOM   4122  O O   . ASN B 1 82  ? 219.726 151.128 180.954 1.00 101.36 ? 103 ASN B O   1 
ATOM   4123  C CB  . ASN B 1 82  ? 218.504 152.217 178.116 1.00 101.36 ? 103 ASN B CB  1 
ATOM   4124  C CG  . ASN B 1 82  ? 218.570 152.521 176.631 1.00 101.36 ? 103 ASN B CG  1 
ATOM   4125  O OD1 . ASN B 1 82  ? 219.399 153.313 176.183 1.00 101.36 ? 103 ASN B OD1 1 
ATOM   4126  N ND2 . ASN B 1 82  ? 217.688 151.896 175.861 1.00 101.36 ? 103 ASN B ND2 1 
ATOM   4127  N N   . ILE B 1 83  ? 219.752 153.384 180.803 1.00 95.49  ? 104 ILE B N   1 
ATOM   4128  C CA  . ILE B 1 83  ? 219.927 153.581 182.242 1.00 95.49  ? 104 ILE B CA  1 
ATOM   4129  C C   . ILE B 1 83  ? 218.667 153.189 183.022 1.00 95.49  ? 104 ILE B C   1 
ATOM   4130  O O   . ILE B 1 83  ? 218.694 152.243 183.815 1.00 95.49  ? 104 ILE B O   1 
ATOM   4131  C CB  . ILE B 1 83  ? 220.419 155.021 182.536 1.00 95.49  ? 104 ILE B CB  1 
ATOM   4132  C CG1 . ILE B 1 83  ? 220.692 155.229 184.033 1.00 95.49  ? 104 ILE B CG1 1 
ATOM   4133  C CG2 . ILE B 1 83  ? 219.628 156.148 181.799 1.00 95.49  ? 104 ILE B CG2 1 
ATOM   4134  C CD1 . ILE B 1 83  ? 221.859 154.425 184.558 1.00 95.49  ? 104 ILE B CD1 1 
ATOM   4135  N N   . PHE B 1 84  ? 217.541 153.863 182.776 1.00 87.21  ? 105 PHE B N   1 
ATOM   4136  C CA  . PHE B 1 84  ? 216.301 153.691 183.531 1.00 87.21  ? 105 PHE B CA  1 
ATOM   4137  C C   . PHE B 1 84  ? 215.125 154.232 182.730 1.00 87.21  ? 105 PHE B C   1 
ATOM   4138  O O   . PHE B 1 84  ? 215.232 154.431 181.516 1.00 87.21  ? 105 PHE B O   1 
ATOM   4139  C CB  . PHE B 1 84  ? 216.348 154.386 184.899 1.00 87.21  ? 105 PHE B CB  1 
ATOM   4140  C CG  . PHE B 1 84  ? 217.052 153.597 185.970 1.00 87.21  ? 105 PHE B CG  1 
ATOM   4141  C CD1 . PHE B 1 84  ? 218.266 154.025 186.486 1.00 87.21  ? 105 PHE B CD1 1 
ATOM   4142  C CD2 . PHE B 1 84  ? 216.508 152.410 186.442 1.00 87.21  ? 105 PHE B CD2 1 
ATOM   4143  C CE1 . PHE B 1 84  ? 218.918 153.292 187.467 1.00 87.21  ? 105 PHE B CE1 1 
ATOM   4144  C CE2 . PHE B 1 84  ? 217.152 151.671 187.421 1.00 87.21  ? 105 PHE B CE2 1 
ATOM   4145  C CZ  . PHE B 1 84  ? 218.359 152.113 187.934 1.00 87.21  ? 105 PHE B CZ  1 
ATOM   4146  N N   . GLY B 1 85  ? 214.004 154.482 183.401 1.00 76.32  ? 106 GLY B N   1 
ATOM   4147  C CA  . GLY B 1 85  ? 212.857 155.041 182.717 1.00 76.32  ? 106 GLY B CA  1 
ATOM   4148  C C   . GLY B 1 85  ? 211.489 154.615 183.209 1.00 76.32  ? 106 GLY B C   1 
ATOM   4149  O O   . GLY B 1 85  ? 210.489 155.095 182.664 1.00 76.32  ? 106 GLY B O   1 
ATOM   4150  N N   . ALA B 1 86  ? 211.440 153.737 184.221 1.00 64.97  ? 107 ALA B N   1 
ATOM   4151  C CA  . ALA B 1 86  ? 210.222 153.368 184.961 1.00 64.97  ? 107 ALA B CA  1 
ATOM   4152  C C   . ALA B 1 86  ? 209.154 152.779 184.033 1.00 64.97  ? 107 ALA B C   1 
ATOM   4153  O O   . ALA B 1 86  ? 208.151 153.418 183.710 1.00 64.97  ? 107 ALA B O   1 
ATOM   4154  C CB  . ALA B 1 86  ? 209.674 154.559 185.757 1.00 64.97  ? 107 ALA B CB  1 
ATOM   4155  N N   . ILE B 1 87  ? 209.457 151.561 183.565 1.00 58.35  ? 108 ILE B N   1 
ATOM   4156  C CA  . ILE B 1 87  ? 208.691 150.894 182.512 1.00 58.35  ? 108 ILE B CA  1 
ATOM   4157  C C   . ILE B 1 87  ? 207.252 150.668 182.952 1.00 58.35  ? 108 ILE B C   1 
ATOM   4158  O O   . ILE B 1 87  ? 206.990 150.023 183.973 1.00 58.35  ? 108 ILE B O   1 
ATOM   4159  C CB  . ILE B 1 87  ? 209.340 149.549 182.127 1.00 58.35  ? 108 ILE B CB  1 
ATOM   4160  C CG1 . ILE B 1 87  ? 210.773 149.698 181.604 1.00 58.35  ? 108 ILE B CG1 1 
ATOM   4161  C CG2 . ILE B 1 87  ? 208.508 148.856 181.077 1.00 58.35  ? 108 ILE B CG2 1 
ATOM   4162  C CD1 . ILE B 1 87  ? 211.859 149.495 182.636 1.00 58.35  ? 108 ILE B CD1 1 
ATOM   4163  N N   . VAL B 1 88  ? 206.315 151.204 182.175 1.00 59.27  ? 109 VAL B N   1 
ATOM   4164  C CA  . VAL B 1 88  ? 204.892 150.948 182.358 1.00 59.27  ? 109 VAL B CA  1 
ATOM   4165  C C   . VAL B 1 88  ? 204.550 149.716 181.532 1.00 59.27  ? 109 VAL B C   1 
ATOM   4166  O O   . VAL B 1 88  ? 204.750 149.699 180.311 1.00 59.27  ? 109 VAL B O   1 
ATOM   4167  C CB  . VAL B 1 88  ? 204.045 152.163 181.945 1.00 59.27  ? 109 VAL B CB  1 
ATOM   4168  C CG1 . VAL B 1 88  ? 202.592 151.765 181.703 1.00 59.27  ? 109 VAL B CG1 1 
ATOM   4169  C CG2 . VAL B 1 88  ? 204.136 153.255 182.999 1.00 59.27  ? 109 VAL B CG2 1 
ATOM   4170  N N   . ALA B 1 89  ? 204.058 148.673 182.197 1.00 53.89  ? 110 ALA B N   1 
ATOM   4171  C CA  . ALA B 1 89  ? 203.788 147.400 181.538 1.00 53.89  ? 110 ALA B CA  1 
ATOM   4172  C C   . ALA B 1 89  ? 202.431 147.473 180.853 1.00 53.89  ? 110 ALA B C   1 
ATOM   4173  O O   . ALA B 1 89  ? 201.397 147.577 181.518 1.00 53.89  ? 110 ALA B O   1 
ATOM   4174  C CB  . ALA B 1 89  ? 203.834 146.257 182.548 1.00 53.89  ? 110 ALA B CB  1 
ATOM   4175  N N   . GLY B 1 90  ? 202.428 147.399 179.524 1.00 43.42  ? 111 GLY B N   1 
ATOM   4176  C CA  . GLY B 1 90  ? 201.197 147.506 178.765 1.00 43.42  ? 111 GLY B CA  1 
ATOM   4177  C C   . GLY B 1 90  ? 200.358 146.251 178.710 1.00 43.42  ? 111 GLY B C   1 
ATOM   4178  O O   . GLY B 1 90  ? 199.290 146.268 178.091 1.00 43.42  ? 111 GLY B O   1 
ATOM   4179  N N   . ALA B 1 91  ? 200.815 145.160 179.326 1.00 48.37  ? 112 ALA B N   1 
ATOM   4180  C CA  . ALA B 1 91  ? 200.045 143.922 179.319 1.00 48.37  ? 112 ALA B CA  1 
ATOM   4181  C C   . ALA B 1 91  ? 198.825 144.021 180.227 1.00 48.37  ? 112 ALA B C   1 
ATOM   4182  O O   . ALA B 1 91  ? 197.791 143.396 179.967 1.00 48.37  ? 112 ALA B O   1 
ATOM   4183  C CB  . ALA B 1 91  ? 200.935 142.751 179.737 1.00 48.37  ? 112 ALA B CB  1 
ATOM   4184  N N   . ALA B 1 92  ? 198.925 144.805 181.302 1.00 42.22  ? 113 ALA B N   1 
ATOM   4185  C CA  . ALA B 1 92  ? 197.898 144.829 182.336 1.00 42.22  ? 113 ALA B CA  1 
ATOM   4186  C C   . ALA B 1 92  ? 197.203 146.182 182.462 1.00 42.22  ? 113 ALA B C   1 
ATOM   4187  O O   . ALA B 1 92  ? 196.528 146.431 183.465 1.00 42.22  ? 113 ALA B O   1 
ATOM   4188  C CB  . ALA B 1 92  ? 198.499 144.416 183.680 1.00 42.22  ? 113 ALA B CB  1 
ATOM   4189  N N   . LEU B 1 93  ? 197.346 147.060 181.472 1.00 36.23  ? 114 LEU B N   1 
ATOM   4190  C CA  . LEU B 1 93  ? 196.571 148.295 181.429 1.00 36.23  ? 114 LEU B CA  1 
ATOM   4191  C C   . LEU B 1 93  ? 195.316 148.187 180.577 1.00 36.23  ? 114 LEU B C   1 
ATOM   4192  O O   . LEU B 1 93  ? 194.413 149.014 180.734 1.00 36.23  ? 114 LEU B O   1 
ATOM   4193  C CB  . LEU B 1 93  ? 197.420 149.467 180.919 1.00 36.23  ? 114 LEU B CB  1 
ATOM   4194  C CG  . LEU B 1 93  ? 198.172 150.373 181.900 1.00 36.23  ? 114 LEU B CG  1 
ATOM   4195  C CD1 . LEU B 1 93  ? 197.177 151.136 182.761 1.00 36.23  ? 114 LEU B CD1 1 
ATOM   4196  C CD2 . LEU B 1 93  ? 199.138 149.619 182.773 1.00 36.23  ? 114 LEU B CD2 1 
ATOM   4197  N N   . GLY B 1 94  ? 195.221 147.183 179.707 1.00 31.73  ? 115 GLY B N   1 
ATOM   4198  C CA  . GLY B 1 94  ? 194.093 147.091 178.802 1.00 31.73  ? 115 GLY B CA  1 
ATOM   4199  C C   . GLY B 1 94  ? 194.078 148.209 177.780 1.00 31.73  ? 115 GLY B C   1 
ATOM   4200  O O   . GLY B 1 94  ? 194.873 148.210 176.836 1.00 31.73  ? 115 GLY B O   1 
ATOM   4201  N N   . ILE B 1 95  ? 193.165 149.158 177.953 1.00 30.59  ? 116 ILE B N   1 
ATOM   4202  C CA  . ILE B 1 95  ? 193.064 150.334 177.096 1.00 30.59  ? 116 ILE B CA  1 
ATOM   4203  C C   . ILE B 1 95  ? 193.345 151.555 177.961 1.00 30.59  ? 116 ILE B C   1 
ATOM   4204  O O   . ILE B 1 95  ? 192.681 151.762 178.985 1.00 30.59  ? 116 ILE B O   1 
ATOM   4205  C CB  . ILE B 1 95  ? 191.687 150.446 176.412 1.00 30.59  ? 116 ILE B CB  1 
ATOM   4206  C CG1 . ILE B 1 95  ? 191.422 149.278 175.448 1.00 30.59  ? 116 ILE B CG1 1 
ATOM   4207  C CG2 . ILE B 1 95  ? 191.561 151.764 175.668 1.00 30.59  ? 116 ILE B CG2 1 
ATOM   4208  C CD1 . ILE B 1 95  ? 190.685 148.076 176.044 1.00 30.59  ? 116 ILE B CD1 1 
ATOM   4209  N N   . ALA B 1 96  ? 194.327 152.359 177.556 1.00 35.74  ? 117 ALA B N   1 
ATOM   4210  C CA  . ALA B 1 96  ? 194.717 153.533 178.322 1.00 35.74  ? 117 ALA B CA  1 
ATOM   4211  C C   . ALA B 1 96  ? 195.154 154.638 177.372 1.00 35.74  ? 117 ALA B C   1 
ATOM   4212  O O   . ALA B 1 96  ? 195.541 154.384 176.229 1.00 35.74  ? 117 ALA B O   1 
ATOM   4213  C CB  . ALA B 1 96  ? 195.841 153.208 179.313 1.00 35.74  ? 117 ALA B CB  1 
ATOM   4214  N N   . THR B 1 97  ? 195.092 155.873 177.864 1.00 41.04  ? 118 THR B N   1 
ATOM   4215  C CA  . THR B 1 97  ? 195.499 157.045 177.107 1.00 41.04  ? 118 THR B CA  1 
ATOM   4216  C C   . THR B 1 97  ? 196.863 157.530 177.593 1.00 41.04  ? 118 THR B C   1 
ATOM   4217  O O   . THR B 1 97  ? 197.506 156.911 178.442 1.00 41.04  ? 118 THR B O   1 
ATOM   4218  C CB  . THR B 1 97  ? 194.452 158.155 177.224 1.00 41.04  ? 118 THR B CB  1 
ATOM   4219  O OG1 . THR B 1 97  ? 194.530 158.752 178.524 1.00 41.04  ? 118 THR B OG1 1 
ATOM   4220  C CG2 . THR B 1 97  ? 193.056 157.593 177.017 1.00 41.04  ? 118 THR B CG2 1 
ATOM   4221  N N   . ALA B 1 98  ? 197.308 158.661 177.038 1.00 39.78  ? 119 ALA B N   1 
ATOM   4222  C CA  . ALA B 1 98  ? 198.618 159.201 177.393 1.00 39.78  ? 119 ALA B CA  1 
ATOM   4223  C C   . ALA B 1 98  ? 198.616 159.806 178.792 1.00 39.78  ? 119 ALA B C   1 
ATOM   4224  O O   . ALA B 1 98  ? 199.596 159.663 179.538 1.00 39.78  ? 119 ALA B O   1 
ATOM   4225  C CB  . ALA B 1 98  ? 199.048 160.243 176.362 1.00 39.78  ? 119 ALA B CB  1 
ATOM   4226  N N   . ALA B 1 99  ? 197.527 160.488 179.160 1.00 41.67  ? 120 ALA B N   1 
ATOM   4227  C CA  . ALA B 1 99  ? 197.432 161.106 180.478 1.00 41.67  ? 120 ALA B CA  1 
ATOM   4228  C C   . ALA B 1 99  ? 197.356 160.064 181.587 1.00 41.67  ? 120 ALA B C   1 
ATOM   4229  O O   . ALA B 1 99  ? 197.860 160.302 182.691 1.00 41.67  ? 120 ALA B O   1 
ATOM   4230  C CB  . ALA B 1 99  ? 196.220 162.034 180.536 1.00 41.67  ? 120 ALA B CB  1 
ATOM   4231  N N   . GLN B 1 100 ? 196.754 158.904 181.306 1.00 41.72  ? 121 GLN B N   1 
ATOM   4232  C CA  . GLN B 1 100 ? 196.719 157.827 182.290 1.00 41.72  ? 121 GLN B CA  1 
ATOM   4233  C C   . GLN B 1 100 ? 198.112 157.259 182.541 1.00 41.72  ? 121 GLN B C   1 
ATOM   4234  O O   . GLN B 1 100 ? 198.478 156.993 183.691 1.00 41.72  ? 121 GLN B O   1 
ATOM   4235  C CB  . GLN B 1 100 ? 195.758 156.731 181.831 1.00 41.72  ? 121 GLN B CB  1 
ATOM   4236  C CG  . GLN B 1 100 ? 194.366 157.245 181.492 1.00 41.72  ? 121 GLN B CG  1 
ATOM   4237  C CD  . GLN B 1 100 ? 193.385 156.132 181.188 1.00 41.72  ? 121 GLN B CD  1 
ATOM   4238  O OE1 . GLN B 1 100 ? 193.731 154.953 181.238 1.00 41.72  ? 121 GLN B OE1 1 
ATOM   4239  N NE2 . GLN B 1 100 ? 192.149 156.504 180.874 1.00 41.72  ? 121 GLN B NE2 1 
ATOM   4240  N N   . VAL B 1 101 ? 198.909 157.099 181.479 1.00 35.58  ? 122 VAL B N   1 
ATOM   4241  C CA  . VAL B 1 101 ? 200.289 156.636 181.616 1.00 35.58  ? 122 VAL B CA  1 
ATOM   4242  C C   . VAL B 1 101 ? 201.129 157.668 182.367 1.00 35.58  ? 122 VAL B C   1 
ATOM   4243  O O   . VAL B 1 101 ? 201.957 157.313 183.219 1.00 35.58  ? 122 VAL B O   1 
ATOM   4244  C CB  . VAL B 1 101 ? 200.869 156.312 180.224 1.00 35.58  ? 122 VAL B CB  1 
ATOM   4245  C CG1 . VAL B 1 101 ? 202.348 155.955 180.296 1.00 35.58  ? 122 VAL B CG1 1 
ATOM   4246  C CG2 . VAL B 1 101 ? 200.096 155.173 179.586 1.00 35.58  ? 122 VAL B CG2 1 
ATOM   4247  N N   . THR B 1 102 ? 200.894 158.958 182.090 1.00 33.48  ? 123 THR B N   1 
ATOM   4248  C CA  . THR B 1 102 ? 201.581 160.030 182.810 1.00 33.48  ? 123 THR B CA  1 
ATOM   4249  C C   . THR B 1 102 ? 201.225 160.022 184.296 1.00 33.48  ? 123 THR B C   1 
ATOM   4250  O O   . THR B 1 102 ? 202.098 160.209 185.154 1.00 33.48  ? 123 THR B O   1 
ATOM   4251  C CB  . THR B 1 102 ? 201.234 161.378 182.170 1.00 33.48  ? 123 THR B CB  1 
ATOM   4252  O OG1 . THR B 1 102 ? 201.635 161.367 180.795 1.00 33.48  ? 123 THR B OG1 1 
ATOM   4253  C CG2 . THR B 1 102 ? 201.948 162.527 182.870 1.00 33.48  ? 123 THR B CG2 1 
ATOM   4254  N N   . SER B 1 103 ? 199.957 159.749 184.619 1.00 33.42  ? 124 SER B N   1 
ATOM   4255  C CA  . SER B 1 103 ? 199.543 159.641 186.016 1.00 33.42  ? 124 SER B CA  1 
ATOM   4256  C C   . SER B 1 103 ? 200.163 158.424 186.700 1.00 33.42  ? 124 SER B C   1 
ATOM   4257  O O   . SER B 1 103 ? 200.527 158.495 187.879 1.00 33.42  ? 124 SER B O   1 
ATOM   4258  C CB  . SER B 1 103 ? 198.020 159.589 186.105 1.00 33.42  ? 124 SER B CB  1 
ATOM   4259  O OG  . SER B 1 103 ? 197.441 160.788 185.623 1.00 33.42  ? 124 SER B OG  1 
ATOM   4260  N N   . VAL B 1 104 ? 200.288 157.305 185.976 1.00 31.63  ? 125 VAL B N   1 
ATOM   4261  C CA  . VAL B 1 104 ? 200.938 156.108 186.518 1.00 31.63  ? 125 VAL B CA  1 
ATOM   4262  C C   . VAL B 1 104 ? 202.405 156.390 186.845 1.00 31.63  ? 125 VAL B C   1 
ATOM   4263  O O   . VAL B 1 104 ? 202.908 156.012 187.916 1.00 31.63  ? 125 VAL B O   1 
ATOM   4264  C CB  . VAL B 1 104 ? 200.783 154.933 185.530 1.00 31.63  ? 125 VAL B CB  1 
ATOM   4265  C CG1 . VAL B 1 104 ? 201.676 153.777 185.901 1.00 31.63  ? 125 VAL B CG1 1 
ATOM   4266  C CG2 . VAL B 1 104 ? 199.354 154.451 185.510 1.00 31.63  ? 125 VAL B CG2 1 
ATOM   4267  N N   . VAL B 1 105 ? 203.094 157.100 185.946 1.00 33.80  ? 126 VAL B N   1 
ATOM   4268  C CA  . VAL B 1 105 ? 204.478 157.506 186.192 1.00 33.80  ? 126 VAL B CA  1 
ATOM   4269  C C   . VAL B 1 105 ? 204.557 158.492 187.362 1.00 33.80  ? 126 VAL B C   1 
ATOM   4270  O O   . VAL B 1 105 ? 205.510 158.461 188.150 1.00 33.80  ? 126 VAL B O   1 
ATOM   4271  C CB  . VAL B 1 105 ? 205.087 158.067 184.889 1.00 33.80  ? 126 VAL B CB  1 
ATOM   4272  C CG1 . VAL B 1 105 ? 206.484 158.641 185.097 1.00 33.80  ? 126 VAL B CG1 1 
ATOM   4273  C CG2 . VAL B 1 105 ? 205.158 156.966 183.850 1.00 33.80  ? 126 VAL B CG2 1 
ATOM   4274  N N   . ALA B 1 106 ? 203.534 159.341 187.525 1.00 32.04  ? 127 ALA B N   1 
ATOM   4275  C CA  . ALA B 1 106 ? 203.489 160.264 188.662 1.00 32.04  ? 127 ALA B CA  1 
ATOM   4276  C C   . ALA B 1 106 ? 203.358 159.529 189.997 1.00 32.04  ? 127 ALA B C   1 
ATOM   4277  O O   . ALA B 1 106 ? 204.027 159.892 190.974 1.00 32.04  ? 127 ALA B O   1 
ATOM   4278  C CB  . ALA B 1 106 ? 202.342 161.257 188.487 1.00 32.04  ? 127 ALA B CB  1 
ATOM   4279  N N   . LEU B 1 107 ? 202.505 158.499 190.059 1.00 28.50  ? 128 LEU B N   1 
ATOM   4280  C CA  . LEU B 1 107 ? 202.431 157.662 191.262 1.00 28.50  ? 128 LEU B CA  1 
ATOM   4281  C C   . LEU B 1 107 ? 203.736 156.917 191.528 1.00 28.50  ? 128 LEU B C   1 
ATOM   4282  O O   . LEU B 1 107 ? 204.170 156.809 192.686 1.00 28.50  ? 128 LEU B O   1 
ATOM   4283  C CB  . LEU B 1 107 ? 201.271 156.668 191.179 1.00 28.50  ? 128 LEU B CB  1 
ATOM   4284  C CG  . LEU B 1 107 ? 199.852 157.040 191.625 1.00 28.50  ? 128 LEU B CG  1 
ATOM   4285  C CD1 . LEU B 1 107 ? 199.104 157.990 190.725 1.00 28.50  ? 128 LEU B CD1 1 
ATOM   4286  C CD2 . LEU B 1 107 ? 199.070 155.751 191.770 1.00 28.50  ? 128 LEU B CD2 1 
ATOM   4287  N N   . HIS B 1 108 ? 204.377 156.397 190.474 1.00 33.10  ? 129 HIS B N   1 
ATOM   4288  C CA  . HIS B 1 108 ? 205.647 155.699 190.667 1.00 33.10  ? 129 HIS B CA  1 
ATOM   4289  C C   . HIS B 1 108 ? 206.757 156.651 191.106 1.00 33.10  ? 129 HIS B C   1 
ATOM   4290  O O   . HIS B 1 108 ? 207.692 156.235 191.798 1.00 33.10  ? 129 HIS B O   1 
ATOM   4291  C CB  . HIS B 1 108 ? 206.052 154.968 189.389 1.00 33.10  ? 129 HIS B CB  1 
ATOM   4292  C CG  . HIS B 1 108 ? 207.252 154.091 189.557 1.00 33.10  ? 129 HIS B CG  1 
ATOM   4293  N ND1 . HIS B 1 108 ? 207.198 152.872 190.197 1.00 33.10  ? 129 HIS B ND1 1 
ATOM   4294  C CD2 . HIS B 1 108 ? 208.541 154.261 189.180 1.00 33.10  ? 129 HIS B CD2 1 
ATOM   4295  C CE1 . HIS B 1 108 ? 208.400 152.326 190.201 1.00 33.10  ? 129 HIS B CE1 1 
ATOM   4296  N NE2 . HIS B 1 108 ? 209.234 153.148 189.590 1.00 33.10  ? 129 HIS B NE2 1 
ATOM   4297  N N   . LYS B 1 109 ? 206.666 157.924 190.722 1.00 33.47  ? 130 LYS B N   1 
ATOM   4298  C CA  . LYS B 1 109 ? 207.619 158.923 191.189 1.00 33.47  ? 130 LYS B CA  1 
ATOM   4299  C C   . LYS B 1 109 ? 207.336 159.343 192.628 1.00 33.47  ? 130 LYS B C   1 
ATOM   4300  O O   . LYS B 1 109 ? 208.270 159.626 193.387 1.00 33.47  ? 130 LYS B O   1 
ATOM   4301  C CB  . LYS B 1 109 ? 207.590 160.139 190.262 1.00 33.47  ? 130 LYS B CB  1 
ATOM   4302  C CG  . LYS B 1 109 ? 208.796 161.054 190.386 1.00 33.47  ? 130 LYS B CG  1 
ATOM   4303  C CD  . LYS B 1 109 ? 210.053 160.379 189.866 1.00 33.47  ? 130 LYS B CD  1 
ATOM   4304  C CE  . LYS B 1 109 ? 209.937 160.069 188.383 1.00 33.47  ? 130 LYS B CE  1 
ATOM   4305  N NZ  . LYS B 1 109 ? 209.851 161.311 187.569 1.00 33.47  ? 130 LYS B NZ  1 
ATOM   4306  N N   . SER B 1 110 ? 206.064 159.395 193.021 1.00 30.02  ? 131 SER B N   1 
ATOM   4307  C CA  . SER B 1 110 ? 205.680 159.878 194.343 1.00 30.02  ? 131 SER B CA  1 
ATOM   4308  C C   . SER B 1 110 ? 205.541 158.767 195.380 1.00 30.02  ? 131 SER B C   1 
ATOM   4309  O O   . SER B 1 110 ? 205.091 159.047 196.499 1.00 30.02  ? 131 SER B O   1 
ATOM   4310  C CB  . SER B 1 110 ? 204.370 160.661 194.254 1.00 30.02  ? 131 SER B CB  1 
ATOM   4311  O OG  . SER B 1 110 ? 204.003 161.171 195.522 1.00 30.02  ? 131 SER B OG  1 
ATOM   4312  N N   . ASN B 1 111 ? 205.884 157.523 195.014 1.00 32.33  ? 132 ASN B N   1 
ATOM   4313  C CA  . ASN B 1 111 ? 205.813 156.386 195.938 1.00 32.33  ? 132 ASN B CA  1 
ATOM   4314  C C   . ASN B 1 111 ? 206.674 156.592 197.189 1.00 32.33  ? 132 ASN B C   1 
ATOM   4315  O O   . ASN B 1 111 ? 206.231 156.287 198.306 1.00 32.33  ? 132 ASN B O   1 
ATOM   4316  C CB  . ASN B 1 111 ? 206.244 155.115 195.196 1.00 32.33  ? 132 ASN B CB  1 
ATOM   4317  C CG  . ASN B 1 111 ? 205.927 153.826 195.954 1.00 32.33  ? 132 ASN B CG  1 
ATOM   4318  O OD1 . ASN B 1 111 ? 205.373 153.835 197.053 1.00 32.33  ? 132 ASN B OD1 1 
ATOM   4319  N ND2 . ASN B 1 111 ? 206.293 152.701 195.354 1.00 32.33  ? 132 ASN B ND2 1 
ATOM   4320  N N   . GLN B 1 112 ? 207.900 157.108 197.025 1.00 39.41  ? 133 GLN B N   1 
ATOM   4321  C CA  . GLN B 1 112 ? 208.808 157.267 198.164 1.00 39.41  ? 133 GLN B CA  1 
ATOM   4322  C C   . GLN B 1 112 ? 208.304 158.315 199.152 1.00 39.41  ? 133 GLN B C   1 
ATOM   4323  O O   . GLN B 1 112 ? 208.332 158.094 200.371 1.00 39.41  ? 133 GLN B O   1 
ATOM   4324  C CB  . GLN B 1 112 ? 210.211 157.635 197.681 1.00 39.41  ? 133 GLN B CB  1 
ATOM   4325  C CG  . GLN B 1 112 ? 210.867 156.596 196.791 1.00 39.41  ? 133 GLN B CG  1 
ATOM   4326  C CD  . GLN B 1 112 ? 210.706 156.907 195.317 1.00 39.41  ? 133 GLN B CD  1 
ATOM   4327  O OE1 . GLN B 1 112 ? 209.754 157.572 194.911 1.00 39.41  ? 133 GLN B OE1 1 
ATOM   4328  N NE2 . GLN B 1 112 ? 211.644 156.429 194.506 1.00 39.41  ? 133 GLN B NE2 1 
ATOM   4329  N N   . ASN B 1 113 ? 207.819 159.452 198.648 1.00 34.63  ? 134 ASN B N   1 
ATOM   4330  C CA  . ASN B 1 113 ? 207.286 160.472 199.543 1.00 34.63  ? 134 ASN B CA  1 
ATOM   4331  C C   . ASN B 1 113 ? 205.952 160.048 200.144 1.00 34.63  ? 134 ASN B C   1 
ATOM   4332  O O   . ASN B 1 113 ? 205.635 160.446 201.271 1.00 34.63  ? 134 ASN B O   1 
ATOM   4333  C CB  . ASN B 1 113 ? 207.145 161.804 198.810 1.00 34.63  ? 134 ASN B CB  1 
ATOM   4334  C CG  . ASN B 1 113 ? 207.105 162.983 199.759 1.00 34.63  ? 134 ASN B CG  1 
ATOM   4335  O OD1 . ASN B 1 113 ? 207.830 163.018 200.752 1.00 34.63  ? 134 ASN B OD1 1 
ATOM   4336  N ND2 . ASN B 1 113 ? 206.258 163.957 199.458 1.00 34.63  ? 134 ASN B ND2 1 
ATOM   4337  N N   . ALA B 1 114 ? 205.177 159.224 199.426 1.00 32.34  ? 135 ALA B N   1 
ATOM   4338  C CA  . ALA B 1 114 ? 203.961 158.655 200.000 1.00 32.34  ? 135 ALA B CA  1 
ATOM   4339  C C   . ALA B 1 114 ? 204.281 157.730 201.167 1.00 32.34  ? 135 ALA B C   1 
ATOM   4340  O O   . ALA B 1 114 ? 203.588 157.751 202.190 1.00 32.34  ? 135 ALA B O   1 
ATOM   4341  C CB  . ALA B 1 114 ? 203.172 157.910 198.925 1.00 32.34  ? 135 ALA B CB  1 
ATOM   4342  N N   . ALA B 1 115 ? 205.342 156.928 201.038 1.00 35.53  ? 136 ALA B N   1 
ATOM   4343  C CA  . ALA B 1 115 ? 205.781 156.085 202.150 1.00 35.53  ? 136 ALA B CA  1 
ATOM   4344  C C   . ALA B 1 115 ? 206.317 156.919 203.311 1.00 35.53  ? 136 ALA B C   1 
ATOM   4345  O O   . ALA B 1 115 ? 206.104 156.573 204.482 1.00 35.53  ? 136 ALA B O   1 
ATOM   4346  C CB  . ALA B 1 115 ? 206.839 155.093 201.669 1.00 35.53  ? 136 ALA B CB  1 
ATOM   4347  N N   . LYS B 1 116 ? 207.009 158.023 203.002 1.00 38.88  ? 137 LYS B N   1 
ATOM   4348  C CA  . LYS B 1 116 ? 207.522 158.909 204.048 1.00 38.88  ? 137 LYS B CA  1 
ATOM   4349  C C   . LYS B 1 116 ? 206.396 159.575 204.834 1.00 38.88  ? 137 LYS B C   1 
ATOM   4350  O O   . LYS B 1 116 ? 206.500 159.737 206.056 1.00 38.88  ? 137 LYS B O   1 
ATOM   4351  C CB  . LYS B 1 116 ? 208.443 159.965 203.440 1.00 38.88  ? 137 LYS B CB  1 
ATOM   4352  C CG  . LYS B 1 116 ? 209.835 159.457 203.109 1.00 38.88  ? 137 LYS B CG  1 
ATOM   4353  C CD  . LYS B 1 116 ? 210.809 160.608 202.913 1.00 38.88  ? 137 LYS B CD  1 
ATOM   4354  C CE  . LYS B 1 116 ? 211.001 161.401 204.196 1.00 38.88  ? 137 LYS B CE  1 
ATOM   4355  N NZ  . LYS B 1 116 ? 211.193 160.519 205.380 1.00 38.88  ? 137 LYS B NZ  1 
ATOM   4356  N N   . ILE B 1 117 ? 205.319 159.978 204.154 1.00 37.05  ? 138 ILE B N   1 
ATOM   4357  C CA  . ILE B 1 117 ? 204.158 160.517 204.861 1.00 37.05  ? 138 ILE B CA  1 
ATOM   4358  C C   . ILE B 1 117 ? 203.434 159.413 205.630 1.00 37.05  ? 138 ILE B C   1 
ATOM   4359  O O   . ILE B 1 117 ? 203.008 159.613 206.775 1.00 37.05  ? 138 ILE B O   1 
ATOM   4360  C CB  . ILE B 1 117 ? 203.223 161.252 203.879 1.00 37.05  ? 138 ILE B CB  1 
ATOM   4361  C CG1 . ILE B 1 117 ? 203.952 162.424 203.225 1.00 37.05  ? 138 ILE B CG1 1 
ATOM   4362  C CG2 . ILE B 1 117 ? 201.999 161.791 204.586 1.00 37.05  ? 138 ILE B CG2 1 
ATOM   4363  C CD1 . ILE B 1 117 ? 203.268 162.948 201.982 1.00 37.05  ? 138 ILE B CD1 1 
ATOM   4364  N N   . ASN B 1 118 ? 203.322 158.217 205.036 1.00 39.94  ? 139 ASN B N   1 
ATOM   4365  C CA  . ASN B 1 118 ? 202.632 157.098 205.675 1.00 39.94  ? 139 ASN B CA  1 
ATOM   4366  C C   . ASN B 1 118 ? 203.375 156.550 206.888 1.00 39.94  ? 139 ASN B C   1 
ATOM   4367  O O   . ASN B 1 118 ? 202.774 155.825 207.687 1.00 39.94  ? 139 ASN B O   1 
ATOM   4368  C CB  . ASN B 1 118 ? 202.422 155.969 204.667 1.00 39.94  ? 139 ASN B CB  1 
ATOM   4369  C CG  . ASN B 1 118 ? 201.200 156.180 203.803 1.00 39.94  ? 139 ASN B CG  1 
ATOM   4370  O OD1 . ASN B 1 118 ? 201.266 156.087 202.577 1.00 39.94  ? 139 ASN B OD1 1 
ATOM   4371  N ND2 . ASN B 1 118 ? 200.069 156.457 204.441 1.00 39.94  ? 139 ASN B ND2 1 
ATOM   4372  N N   . SER B 1 119 ? 204.662 156.870 207.039 1.00 43.20  ? 140 SER B N   1 
ATOM   4373  C CA  . SER B 1 119 ? 205.410 156.471 208.228 1.00 43.20  ? 140 SER B CA  1 
ATOM   4374  C C   . SER B 1 119 ? 204.969 157.190 209.504 1.00 43.20  ? 140 SER B C   1 
ATOM   4375  O O   . SER B 1 119 ? 205.384 156.779 210.593 1.00 43.20  ? 140 SER B O   1 
ATOM   4376  C CB  . SER B 1 119 ? 206.904 156.706 208.002 1.00 43.20  ? 140 SER B CB  1 
ATOM   4377  O OG  . SER B 1 119 ? 207.392 155.896 206.948 1.00 43.20  ? 140 SER B OG  1 
ATOM   4378  N N   . LEU B 1 120 ? 204.151 158.241 209.407 1.00 44.28  ? 141 LEU B N   1 
ATOM   4379  C CA  . LEU B 1 120 ? 203.692 158.983 210.576 1.00 44.28  ? 141 LEU B CA  1 
ATOM   4380  C C   . LEU B 1 120 ? 202.184 158.852 210.758 1.00 44.28  ? 141 LEU B C   1 
ATOM   4381  O O   . LEU B 1 120 ? 201.491 159.856 210.960 1.00 44.28  ? 141 LEU B O   1 
ATOM   4382  C CB  . LEU B 1 120 ? 204.081 160.458 210.463 1.00 44.28  ? 141 LEU B CB  1 
ATOM   4383  C CG  . LEU B 1 120 ? 205.578 160.766 210.434 1.00 44.28  ? 141 LEU B CG  1 
ATOM   4384  C CD1 . LEU B 1 120 ? 205.815 162.242 210.161 1.00 44.28  ? 141 LEU B CD1 1 
ATOM   4385  C CD2 . LEU B 1 120 ? 206.231 160.345 211.739 1.00 44.28  ? 141 LEU B CD2 1 
ATOM   4386  N N   . ARG B 1 121 ? 201.675 157.618 210.656 1.00 38.33  ? 142 ARG B N   1 
ATOM   4387  C CA  . ARG B 1 121 ? 200.238 157.368 210.767 1.00 38.33  ? 142 ARG B CA  1 
ATOM   4388  C C   . ARG B 1 121 ? 199.713 157.701 212.161 1.00 38.33  ? 142 ARG B C   1 
ATOM   4389  O O   . ARG B 1 121 ? 198.633 158.290 212.301 1.00 38.33  ? 142 ARG B O   1 
ATOM   4390  C CB  . ARG B 1 121 ? 199.942 155.911 210.402 1.00 38.33  ? 142 ARG B CB  1 
ATOM   4391  C CG  . ARG B 1 121 ? 198.567 155.403 210.810 1.00 38.33  ? 142 ARG B CG  1 
ATOM   4392  C CD  . ARG B 1 121 ? 198.078 154.284 209.903 1.00 38.33  ? 142 ARG B CD  1 
ATOM   4393  N NE  . ARG B 1 121 ? 199.009 153.163 209.841 1.00 38.33  ? 142 ARG B NE  1 
ATOM   4394  C CZ  . ARG B 1 121 ? 199.672 152.799 208.751 1.00 38.33  ? 142 ARG B CZ  1 
ATOM   4395  N NH1 . ARG B 1 121 ? 199.531 153.448 207.607 1.00 38.33  ? 142 ARG B NH1 1 
ATOM   4396  N NH2 . ARG B 1 121 ? 200.496 151.757 208.811 1.00 38.33  ? 142 ARG B NH2 1 
ATOM   4397  N N   . ASP B 1 122 ? 200.475 157.356 213.204 1.00 47.77  ? 143 ASP B N   1 
ATOM   4398  C CA  . ASP B 1 122 ? 200.075 157.711 214.563 1.00 47.77  ? 143 ASP B CA  1 
ATOM   4399  C C   . ASP B 1 122 ? 200.173 159.212 214.811 1.00 47.77  ? 143 ASP B C   1 
ATOM   4400  O O   . ASP B 1 122 ? 199.464 159.743 215.672 1.00 47.77  ? 143 ASP B O   1 
ATOM   4401  C CB  . ASP B 1 122 ? 200.926 156.951 215.579 1.00 47.77  ? 143 ASP B CB  1 
ATOM   4402  C CG  . ASP B 1 122 ? 200.612 155.470 215.608 1.00 47.77  ? 143 ASP B CG  1 
ATOM   4403  O OD1 . ASP B 1 122 ? 199.454 155.102 215.319 1.00 47.77  ? 143 ASP B OD1 1 
ATOM   4404  O OD2 . ASP B 1 122 ? 201.522 154.673 215.919 1.00 47.77  ? 143 ASP B OD2 1 
ATOM   4405  N N   . SER B 1 123 ? 201.041 159.908 214.074 1.00 49.77  ? 144 SER B N   1 
ATOM   4406  C CA  . SER B 1 123 ? 201.100 161.360 214.182 1.00 49.77  ? 144 SER B CA  1 
ATOM   4407  C C   . SER B 1 123 ? 199.932 162.026 213.466 1.00 49.77  ? 144 SER B C   1 
ATOM   4408  O O   . SER B 1 123 ? 199.453 163.075 213.911 1.00 49.77  ? 144 SER B O   1 
ATOM   4409  C CB  . SER B 1 123 ? 202.427 161.876 213.627 1.00 49.77  ? 144 SER B CB  1 
ATOM   4410  O OG  . SER B 1 123 ? 203.516 161.429 214.417 1.00 49.77  ? 144 SER B OG  1 
ATOM   4411  N N   . ILE B 1 124 ? 199.475 161.443 212.354 1.00 42.26  ? 145 ILE B N   1 
ATOM   4412  C CA  . ILE B 1 124 ? 198.364 162.019 211.600 1.00 42.26  ? 145 ILE B CA  1 
ATOM   4413  C C   . ILE B 1 124 ? 197.051 161.867 212.366 1.00 42.26  ? 145 ILE B C   1 
ATOM   4414  O O   . ILE B 1 124 ? 196.248 162.805 212.445 1.00 42.26  ? 145 ILE B O   1 
ATOM   4415  C CB  . ILE B 1 124 ? 198.300 161.381 210.196 1.00 42.26  ? 145 ILE B CB  1 
ATOM   4416  C CG1 . ILE B 1 124 ? 199.436 161.909 209.322 1.00 42.26  ? 145 ILE B CG1 1 
ATOM   4417  C CG2 . ILE B 1 124 ? 196.968 161.645 209.505 1.00 42.26  ? 145 ILE B CG2 1 
ATOM   4418  C CD1 . ILE B 1 124 ? 199.547 161.212 207.986 1.00 42.26  ? 145 ILE B CD1 1 
ATOM   4419  N N   . THR B 1 125 ? 196.832 160.708 212.981 1.00 46.08  ? 146 THR B N   1 
ATOM   4420  C CA  . THR B 1 125 ? 195.553 160.412 213.617 1.00 46.08  ? 146 THR B CA  1 
ATOM   4421  C C   . THR B 1 125 ? 195.375 161.069 214.983 1.00 46.08  ? 146 THR B C   1 
ATOM   4422  O O   . THR B 1 125 ? 194.287 160.963 215.557 1.00 46.08  ? 146 THR B O   1 
ATOM   4423  C CB  . THR B 1 125 ? 195.377 158.897 213.761 1.00 46.08  ? 146 THR B CB  1 
ATOM   4424  O OG1 . THR B 1 125 ? 194.025 158.605 214.131 1.00 46.08  ? 146 THR B OG1 1 
ATOM   4425  C CG2 . THR B 1 125 ? 196.317 158.349 214.823 1.00 46.08  ? 146 THR B CG2 1 
ATOM   4426  N N   . LYS B 1 126 ? 196.395 161.738 215.520 1.00 46.18  ? 147 LYS B N   1 
ATOM   4427  C CA  . LYS B 1 126 ? 196.323 162.300 216.862 1.00 46.18  ? 147 LYS B CA  1 
ATOM   4428  C C   . LYS B 1 126 ? 195.992 163.788 216.887 1.00 46.18  ? 147 LYS B C   1 
ATOM   4429  O O   . LYS B 1 126 ? 195.927 164.372 217.975 1.00 46.18  ? 147 LYS B O   1 
ATOM   4430  C CB  . LYS B 1 126 ? 197.641 162.048 217.608 1.00 46.18  ? 147 LYS B CB  1 
ATOM   4431  C CG  . LYS B 1 126 ? 198.784 162.977 217.221 1.00 46.18  ? 147 LYS B CG  1 
ATOM   4432  C CD  . LYS B 1 126 ? 200.125 162.407 217.647 1.00 46.18  ? 147 LYS B CD  1 
ATOM   4433  C CE  . LYS B 1 126 ? 201.211 163.469 217.612 1.00 46.18  ? 147 LYS B CE  1 
ATOM   4434  N NZ  . LYS B 1 126 ? 201.305 164.126 216.279 1.00 46.18  ? 147 LYS B NZ  1 
ATOM   4435  N N   . THR B 1 127 ? 195.766 164.409 215.731 1.00 43.80  ? 148 THR B N   1 
ATOM   4436  C CA  . THR B 1 127 ? 195.463 165.834 215.684 1.00 43.80  ? 148 THR B CA  1 
ATOM   4437  C C   . THR B 1 127 ? 194.070 166.127 216.233 1.00 43.80  ? 148 THR B C   1 
ATOM   4438  O O   . THR B 1 127 ? 193.133 165.342 216.068 1.00 43.80  ? 148 THR B O   1 
ATOM   4439  C CB  . THR B 1 127 ? 195.570 166.361 214.253 1.00 43.80  ? 148 THR B CB  1 
ATOM   4440  O OG1 . THR B 1 127 ? 194.413 165.971 213.504 1.00 43.80  ? 148 THR B OG1 1 
ATOM   4441  C CG2 . THR B 1 127 ? 196.829 165.839 213.582 1.00 43.80  ? 148 THR B CG2 1 
ATOM   4442  N N   . ASN B 1 128 ? 193.941 167.286 216.888 1.00 43.11  ? 149 ASN B N   1 
ATOM   4443  C CA  . ASN B 1 128 ? 192.671 167.676 217.488 1.00 43.11  ? 149 ASN B CA  1 
ATOM   4444  C C   . ASN B 1 128 ? 192.314 169.130 217.195 1.00 43.11  ? 149 ASN B C   1 
ATOM   4445  O O   . ASN B 1 128 ? 191.540 169.731 217.949 1.00 43.11  ? 149 ASN B O   1 
ATOM   4446  C CB  . ASN B 1 128 ? 192.689 167.453 219.002 1.00 43.11  ? 149 ASN B CB  1 
ATOM   4447  C CG  . ASN B 1 128 ? 193.889 168.091 219.669 1.00 43.11  ? 149 ASN B CG  1 
ATOM   4448  O OD1 . ASN B 1 128 ? 195.019 167.629 219.513 1.00 43.11  ? 149 ASN B OD1 1 
ATOM   4449  N ND2 . ASN B 1 128 ? 193.651 169.162 220.415 1.00 43.11  ? 149 ASN B ND2 1 
ATOM   4450  N N   . GLN B 1 129 ? 192.857 169.711 216.130 1.00 40.25  ? 150 GLN B N   1 
ATOM   4451  C CA  . GLN B 1 129 ? 192.493 171.050 215.697 1.00 40.25  ? 150 GLN B CA  1 
ATOM   4452  C C   . GLN B 1 129 ? 192.102 171.009 214.228 1.00 40.25  ? 150 GLN B C   1 
ATOM   4453  O O   . GLN B 1 129 ? 192.196 169.971 213.567 1.00 40.25  ? 150 GLN B O   1 
ATOM   4454  C CB  . GLN B 1 129 ? 193.633 172.052 215.928 1.00 40.25  ? 150 GLN B CB  1 
ATOM   4455  C CG  . GLN B 1 129 ? 193.837 172.420 217.387 1.00 40.25  ? 150 GLN B CG  1 
ATOM   4456  C CD  . GLN B 1 129 ? 194.926 173.455 217.582 1.00 40.25  ? 150 GLN B CD  1 
ATOM   4457  O OE1 . GLN B 1 129 ? 195.597 173.856 216.631 1.00 40.25  ? 150 GLN B OE1 1 
ATOM   4458  N NE2 . GLN B 1 129 ? 195.102 173.902 218.820 1.00 40.25  ? 150 GLN B NE2 1 
ATOM   4459  N N   . ALA B 1 130 ? 191.631 172.154 213.730 1.00 26.32  ? 151 ALA B N   1 
ATOM   4460  C CA  . ALA B 1 130 ? 191.204 172.285 212.343 1.00 26.32  ? 151 ALA B CA  1 
ATOM   4461  C C   . ALA B 1 130 ? 192.368 172.110 211.377 1.00 26.32  ? 151 ALA B C   1 
ATOM   4462  O O   . ALA B 1 130 ? 192.387 171.156 210.597 1.00 26.32  ? 151 ALA B O   1 
ATOM   4463  C CB  . ALA B 1 130 ? 190.532 173.641 212.118 1.00 26.32  ? 151 ALA B CB  1 
ATOM   4464  N N   . VAL B 1 131 ? 193.341 173.019 211.421 1.00 25.52  ? 152 VAL B N   1 
ATOM   4465  C CA  . VAL B 1 131 ? 194.542 172.953 210.593 1.00 25.52  ? 152 VAL B CA  1 
ATOM   4466  C C   . VAL B 1 131 ? 195.756 173.109 211.497 1.00 25.52  ? 152 VAL B C   1 
ATOM   4467  O O   . VAL B 1 131 ? 195.841 174.077 212.260 1.00 25.52  ? 152 VAL B O   1 
ATOM   4468  C CB  . VAL B 1 131 ? 194.560 174.040 209.497 1.00 25.52  ? 152 VAL B CB  1 
ATOM   4469  C CG1 . VAL B 1 131 ? 195.824 173.933 208.665 1.00 25.52  ? 152 VAL B CG1 1 
ATOM   4470  C CG2 . VAL B 1 131 ? 193.341 173.943 208.587 1.00 25.52  ? 152 VAL B CG2 1 
ATOM   4471  N N   . GLU B 1 132 ? 196.694 172.167 211.413 1.00 33.49  ? 153 GLU B N   1 
ATOM   4472  C CA  . GLU B 1 132 ? 197.978 172.336 212.076 1.00 33.49  ? 153 GLU B CA  1 
ATOM   4473  C C   . GLU B 1 132 ? 199.062 171.678 211.235 1.00 33.49  ? 153 GLU B C   1 
ATOM   4474  O O   . GLU B 1 132 ? 198.793 171.083 210.188 1.00 33.49  ? 153 GLU B O   1 
ATOM   4475  C CB  . GLU B 1 132 ? 197.970 171.768 213.498 1.00 33.49  ? 153 GLU B CB  1 
ATOM   4476  C CG  . GLU B 1 132 ? 197.849 170.264 213.595 1.00 33.49  ? 153 GLU B CG  1 
ATOM   4477  C CD  . GLU B 1 132 ? 197.787 169.798 215.034 1.00 33.49  ? 153 GLU B CD  1 
ATOM   4478  O OE1 . GLU B 1 132 ? 197.784 170.660 215.937 1.00 33.49  ? 153 GLU B OE1 1 
ATOM   4479  O OE2 . GLU B 1 132 ? 197.775 168.576 215.271 1.00 33.49  ? 153 GLU B OE2 1 
ATOM   4480  N N   . GLN B 1 133 ? 200.300 171.796 211.708 1.00 37.87  ? 154 GLN B N   1 
ATOM   4481  C CA  . GLN B 1 133 ? 201.475 171.331 210.989 1.00 37.87  ? 154 GLN B CA  1 
ATOM   4482  C C   . GLN B 1 133 ? 202.204 170.269 211.801 1.00 37.87  ? 154 GLN B C   1 
ATOM   4483  O O   . GLN B 1 133 ? 202.195 170.292 213.035 1.00 37.87  ? 154 GLN B O   1 
ATOM   4484  C CB  . GLN B 1 133 ? 202.432 172.491 210.688 1.00 37.87  ? 154 GLN B CB  1 
ATOM   4485  C CG  . GLN B 1 133 ? 201.785 173.670 209.977 1.00 37.87  ? 154 GLN B CG  1 
ATOM   4486  C CD  . GLN B 1 133 ? 201.467 173.382 208.525 1.00 37.87  ? 154 GLN B CD  1 
ATOM   4487  O OE1 . GLN B 1 133 ? 202.335 172.967 207.758 1.00 37.87  ? 154 GLN B OE1 1 
ATOM   4488  N NE2 . GLN B 1 133 ? 200.217 173.603 208.138 1.00 37.87  ? 154 GLN B NE2 1 
ATOM   4489  N N   . LEU B 1 134 ? 202.835 169.333 211.095 1.00 46.29  ? 155 LEU B N   1 
ATOM   4490  C CA  . LEU B 1 134 ? 203.680 168.317 211.706 1.00 46.29  ? 155 LEU B CA  1 
ATOM   4491  C C   . LEU B 1 134 ? 205.029 168.303 211.004 1.00 46.29  ? 155 LEU B C   1 
ATOM   4492  O O   . LEU B 1 134 ? 205.126 168.590 209.808 1.00 46.29  ? 155 LEU B O   1 
ATOM   4493  C CB  . LEU B 1 134 ? 203.045 166.921 211.636 1.00 46.29  ? 155 LEU B CB  1 
ATOM   4494  C CG  . LEU B 1 134 ? 201.636 166.745 212.202 1.00 46.29  ? 155 LEU B CG  1 
ATOM   4495  C CD1 . LEU B 1 134 ? 201.063 165.402 211.780 1.00 46.29  ? 155 LEU B CD1 1 
ATOM   4496  C CD2 . LEU B 1 134 ? 201.645 166.874 213.715 1.00 46.29  ? 155 LEU B CD2 1 
ATOM   4497  N N   . SER B 1 135 ? 206.071 167.958 211.756 1.00 58.78  ? 156 SER B N   1 
ATOM   4498  C CA  . SER B 1 135 ? 207.439 167.988 211.241 1.00 58.78  ? 156 SER B CA  1 
ATOM   4499  C C   . SER B 1 135 ? 207.690 166.728 210.423 1.00 58.78  ? 156 SER B C   1 
ATOM   4500  O O   . SER B 1 135 ? 207.871 165.640 210.973 1.00 58.78  ? 156 SER B O   1 
ATOM   4501  C CB  . SER B 1 135 ? 208.436 168.111 212.387 1.00 58.78  ? 156 SER B CB  1 
ATOM   4502  O OG  . SER B 1 135 ? 208.258 169.332 213.084 1.00 58.78  ? 156 SER B OG  1 
ATOM   4503  N N   . LEU B 1 136 ? 207.695 166.876 209.096 1.00 64.63  ? 157 LEU B N   1 
ATOM   4504  C CA  . LEU B 1 136 ? 207.976 165.741 208.222 1.00 64.63  ? 157 LEU B CA  1 
ATOM   4505  C C   . LEU B 1 136 ? 209.453 165.368 208.251 1.00 64.63  ? 157 LEU B C   1 
ATOM   4506  O O   . LEU B 1 136 ? 209.799 164.184 208.334 1.00 64.63  ? 157 LEU B O   1 
ATOM   4507  C CB  . LEU B 1 136 ? 207.533 166.057 206.795 1.00 64.63  ? 157 LEU B CB  1 
ATOM   4508  C CG  . LEU B 1 136 ? 207.664 164.933 205.767 1.00 64.63  ? 157 LEU B CG  1 
ATOM   4509  C CD1 . LEU B 1 136 ? 206.975 163.668 206.255 1.00 64.63  ? 157 LEU B CD1 1 
ATOM   4510  C CD2 . LEU B 1 136 ? 207.106 165.369 204.421 1.00 64.63  ? 157 LEU B CD2 1 
ATOM   4511  N N   . GLY B 1 137 ? 210.330 166.356 208.186 1.00 84.52  ? 158 GLY B N   1 
ATOM   4512  C CA  . GLY B 1 137 ? 211.764 166.126 208.170 1.00 84.52  ? 158 GLY B CA  1 
ATOM   4513  C C   . GLY B 1 137 ? 212.485 167.263 208.854 1.00 84.52  ? 158 GLY B C   1 
ATOM   4514  O O   . GLY B 1 137 ? 211.950 167.889 209.775 1.00 84.52  ? 158 GLY B O   1 
ATOM   4515  N N   . VAL B 1 138 ? 213.712 167.532 208.405 1.00 97.18  ? 159 VAL B N   1 
ATOM   4516  C CA  . VAL B 1 138 ? 214.492 168.604 209.015 1.00 97.18  ? 159 VAL B CA  1 
ATOM   4517  C C   . VAL B 1 138 ? 214.030 169.971 208.519 1.00 97.18  ? 159 VAL B C   1 
ATOM   4518  O O   . VAL B 1 138 ? 214.173 170.974 209.229 1.00 97.18  ? 159 VAL B O   1 
ATOM   4519  C CB  . VAL B 1 138 ? 215.998 168.377 208.775 1.00 97.18  ? 159 VAL B CB  1 
ATOM   4520  C CG1 . VAL B 1 138 ? 216.454 167.112 209.484 1.00 97.18  ? 159 VAL B CG1 1 
ATOM   4521  C CG2 . VAL B 1 138 ? 216.312 168.279 207.287 1.00 97.18  ? 159 VAL B CG2 1 
ATOM   4522  N N   . GLN B 1 139 ? 213.469 170.042 207.307 1.00 101.83 ? 160 GLN B N   1 
ATOM   4523  C CA  . GLN B 1 139 ? 212.953 171.296 206.776 1.00 101.83 ? 160 GLN B CA  1 
ATOM   4524  C C   . GLN B 1 139 ? 211.615 171.153 206.066 1.00 101.83 ? 160 GLN B C   1 
ATOM   4525  O O   . GLN B 1 139 ? 211.061 172.168 205.632 1.00 101.83 ? 160 GLN B O   1 
ATOM   4526  C CB  . GLN B 1 139 ? 213.966 171.935 205.809 1.00 101.83 ? 160 GLN B CB  1 
ATOM   4527  C CG  . GLN B 1 139 ? 215.128 172.641 206.489 1.00 101.83 ? 160 GLN B CG  1 
ATOM   4528  C CD  . GLN B 1 139 ? 214.679 173.831 207.314 1.00 101.83 ? 160 GLN B CD  1 
ATOM   4529  O OE1 . GLN B 1 139 ? 214.782 173.825 208.541 1.00 101.83 ? 160 GLN B OE1 1 
ATOM   4530  N NE2 . GLN B 1 139 ? 214.175 174.860 206.643 1.00 101.83 ? 160 GLN B NE2 1 
ATOM   4531  N N   . GLU B 1 140 ? 211.080 169.945 205.933 1.00 89.85  ? 161 GLU B N   1 
ATOM   4532  C CA  . GLU B 1 140 ? 209.803 169.718 205.276 1.00 89.85  ? 161 GLU B CA  1 
ATOM   4533  C C   . GLU B 1 140 ? 208.718 169.483 206.318 1.00 89.85  ? 161 GLU B C   1 
ATOM   4534  O O   . GLU B 1 140 ? 208.990 169.015 207.427 1.00 89.85  ? 161 GLU B O   1 
ATOM   4535  C CB  . GLU B 1 140 ? 209.877 168.524 204.320 1.00 89.85  ? 161 GLU B CB  1 
ATOM   4536  C CG  . GLU B 1 140 ? 211.013 168.604 203.315 1.00 89.85  ? 161 GLU B CG  1 
ATOM   4537  C CD  . GLU B 1 140 ? 212.211 167.774 203.727 1.00 89.85  ? 161 GLU B CD  1 
ATOM   4538  O OE1 . GLU B 1 140 ? 212.741 168.001 204.835 1.00 89.85  ? 161 GLU B OE1 1 
ATOM   4539  O OE2 . GLU B 1 140 ? 212.622 166.892 202.944 1.00 89.85  ? 161 GLU B OE2 1 
ATOM   4540  N N   . THR B 1 141 ? 207.483 169.816 205.951 1.00 52.63  ? 162 THR B N   1 
ATOM   4541  C CA  . THR B 1 141 ? 206.362 169.681 206.867 1.00 52.63  ? 162 THR B CA  1 
ATOM   4542  C C   . THR B 1 141 ? 205.114 169.295 206.089 1.00 52.63  ? 162 THR B C   1 
ATOM   4543  O O   . THR B 1 141 ? 205.011 169.523 204.881 1.00 52.63  ? 162 THR B O   1 
ATOM   4544  C CB  . THR B 1 141 ? 206.119 170.976 207.654 1.00 52.63  ? 162 THR B CB  1 
ATOM   4545  O OG1 . THR B 1 141 ? 204.940 170.835 208.456 1.00 52.63  ? 162 THR B OG1 1 
ATOM   4546  C CG2 . THR B 1 141 ? 205.950 172.157 206.709 1.00 52.63  ? 162 THR B CG2 1 
ATOM   4547  N N   . VAL B 1 142 ? 204.167 168.689 206.799 1.00 36.46  ? 163 VAL B N   1 
ATOM   4548  C CA  . VAL B 1 142 ? 202.850 168.402 206.255 1.00 36.46  ? 163 VAL B CA  1 
ATOM   4549  C C   . VAL B 1 142 ? 201.859 169.389 206.856 1.00 36.46  ? 163 VAL B C   1 
ATOM   4550  O O   . VAL B 1 142 ? 202.126 170.055 207.861 1.00 36.46  ? 163 VAL B O   1 
ATOM   4551  C CB  . VAL B 1 142 ? 202.406 166.948 206.510 1.00 36.46  ? 163 VAL B CB  1 
ATOM   4552  C CG1 . VAL B 1 142 ? 203.395 165.978 205.889 1.00 36.46  ? 163 VAL B CG1 1 
ATOM   4553  C CG2 . VAL B 1 142 ? 202.256 166.688 207.995 1.00 36.46  ? 163 VAL B CG2 1 
ATOM   4554  N N   . SER B 1 143 ? 200.692 169.472 206.228 1.00 25.34  ? 164 SER B N   1 
ATOM   4555  C CA  . SER B 1 143 ? 199.674 170.477 206.517 1.00 25.34  ? 164 SER B CA  1 
ATOM   4556  C C   . SER B 1 143 ? 198.325 169.808 206.740 1.00 25.34  ? 164 SER B C   1 
ATOM   4557  O O   . SER B 1 143 ? 197.355 170.079 206.028 1.00 25.34  ? 164 SER B O   1 
ATOM   4558  C CB  . SER B 1 143 ? 199.597 171.514 205.403 1.00 25.34  ? 164 SER B CB  1 
ATOM   4559  O OG  . SER B 1 143 ? 199.249 170.910 204.174 1.00 25.34  ? 164 SER B OG  1 
ATOM   4560  N N   . VAL B 1 144 ? 198.299 168.853 207.682 1.00 21.51  ? 165 VAL B N   1 
ATOM   4561  C CA  . VAL B 1 144 ? 197.106 168.058 207.981 1.00 21.51  ? 165 VAL B CA  1 
ATOM   4562  C C   . VAL B 1 144 ? 195.947 168.958 208.401 1.00 21.51  ? 165 VAL B C   1 
ATOM   4563  O O   . VAL B 1 144 ? 196.125 169.957 209.112 1.00 21.51  ? 165 VAL B O   1 
ATOM   4564  C CB  . VAL B 1 144 ? 197.449 166.987 209.037 1.00 21.51  ? 165 VAL B CB  1 
ATOM   4565  C CG1 . VAL B 1 144 ? 197.907 167.594 210.364 1.00 21.51  ? 165 VAL B CG1 1 
ATOM   4566  C CG2 . VAL B 1 144 ? 196.290 166.014 209.247 1.00 21.51  ? 165 VAL B CG2 1 
ATOM   4567  N N   . LEU B 1 145 ? 194.758 168.652 207.884 1.00 20.33  ? 166 LEU B N   1 
ATOM   4568  C CA  . LEU B 1 145 ? 193.620 169.551 207.991 1.00 20.33  ? 166 LEU B CA  1 
ATOM   4569  C C   . LEU B 1 145 ? 192.319 168.759 207.963 1.00 20.33  ? 166 LEU B C   1 
ATOM   4570  O O   . LEU B 1 145 ? 192.186 167.797 207.204 1.00 20.33  ? 166 LEU B O   1 
ATOM   4571  C CB  . LEU B 1 145 ? 193.677 170.612 206.878 1.00 20.33  ? 166 LEU B CB  1 
ATOM   4572  C CG  . LEU B 1 145 ? 193.779 170.249 205.388 1.00 20.33  ? 166 LEU B CG  1 
ATOM   4573  C CD1 . LEU B 1 145 ? 192.444 169.998 204.713 1.00 20.33  ? 166 LEU B CD1 1 
ATOM   4574  C CD2 . LEU B 1 145 ? 194.547 171.333 204.642 1.00 20.33  ? 166 LEU B CD2 1 
ATOM   4575  N N   . MET B 1 146 ? 191.372 169.167 208.808 1.00 31.38  ? 167 MET B N   1 
ATOM   4576  C CA  . MET B 1 146 ? 190.057 168.540 208.878 1.00 31.38  ? 167 MET B CA  1 
ATOM   4577  C C   . MET B 1 146 ? 189.015 169.615 209.153 1.00 31.38  ? 167 MET B C   1 
ATOM   4578  O O   . MET B 1 146 ? 189.190 170.426 210.068 1.00 31.38  ? 167 MET B O   1 
ATOM   4579  C CB  . MET B 1 146 ? 190.016 167.457 209.962 1.00 31.38  ? 167 MET B CB  1 
ATOM   4580  C CG  . MET B 1 146 ? 188.620 166.962 210.288 1.00 31.38  ? 167 MET B CG  1 
ATOM   4581  S SD  . MET B 1 146 ? 187.920 166.021 208.923 1.00 31.38  ? 167 MET B SD  1 
ATOM   4582  C CE  . MET B 1 146 ? 186.893 164.847 209.796 1.00 31.38  ? 167 MET B CE  1 
ATOM   4583  N N   . GLY B 1 147 ? 187.942 169.622 208.357 1.00 35.24  ? 168 GLY B N   1 
ATOM   4584  C CA  . GLY B 1 147 ? 186.971 170.702 208.442 1.00 35.24  ? 168 GLY B CA  1 
ATOM   4585  C C   . GLY B 1 147 ? 186.098 170.652 209.682 1.00 35.24  ? 168 GLY B C   1 
ATOM   4586  O O   . GLY B 1 147 ? 185.844 171.682 210.313 1.00 35.24  ? 168 GLY B O   1 
ATOM   4587  N N   . LEU B 1 148 ? 185.634 169.464 210.055 1.00 32.02  ? 169 LEU B N   1 
ATOM   4588  C CA  . LEU B 1 148 ? 184.652 169.326 211.124 1.00 32.02  ? 169 LEU B CA  1 
ATOM   4589  C C   . LEU B 1 148 ? 185.255 169.331 212.519 1.00 32.02  ? 169 LEU B C   1 
ATOM   4590  O O   . LEU B 1 148 ? 184.497 169.369 213.491 1.00 32.02  ? 169 LEU B O   1 
ATOM   4591  C CB  . LEU B 1 148 ? 183.834 168.043 210.947 1.00 32.02  ? 169 LEU B CB  1 
ATOM   4592  C CG  . LEU B 1 148 ? 182.528 168.131 210.159 1.00 32.02  ? 169 LEU B CG  1 
ATOM   4593  C CD1 . LEU B 1 148 ? 182.765 168.361 208.681 1.00 32.02  ? 169 LEU B CD1 1 
ATOM   4594  C CD2 . LEU B 1 148 ? 181.707 166.873 210.390 1.00 32.02  ? 169 LEU B CD2 1 
ATOM   4595  N N   . GLN B 1 149 ? 186.585 169.300 212.645 1.00 39.39  ? 170 GLN B N   1 
ATOM   4596  C CA  . GLN B 1 149 ? 187.218 169.205 213.957 1.00 39.39  ? 170 GLN B CA  1 
ATOM   4597  C C   . GLN B 1 149 ? 187.006 170.469 214.790 1.00 39.39  ? 170 GLN B C   1 
ATOM   4598  O O   . GLN B 1 149 ? 186.962 170.388 216.023 1.00 39.39  ? 170 GLN B O   1 
ATOM   4599  C CB  . GLN B 1 149 ? 188.709 168.903 213.775 1.00 39.39  ? 170 GLN B CB  1 
ATOM   4600  C CG  . GLN B 1 149 ? 189.487 168.657 215.054 1.00 39.39  ? 170 GLN B CG  1 
ATOM   4601  C CD  . GLN B 1 149 ? 189.046 167.386 215.749 1.00 39.39  ? 170 GLN B CD  1 
ATOM   4602  O OE1 . GLN B 1 149 ? 188.811 166.363 215.106 1.00 39.39  ? 170 GLN B OE1 1 
ATOM   4603  N NE2 . GLN B 1 149 ? 188.913 167.449 217.067 1.00 39.39  ? 170 GLN B NE2 1 
ATOM   4604  N N   . ASP B 1 150 ? 186.815 171.621 214.141 1.00 51.98  ? 171 ASP B N   1 
ATOM   4605  C CA  . ASP B 1 150 ? 186.444 172.834 214.864 1.00 51.98  ? 171 ASP B CA  1 
ATOM   4606  C C   . ASP B 1 150 ? 185.038 172.732 215.444 1.00 51.98  ? 171 ASP B C   1 
ATOM   4607  O O   . ASP B 1 150 ? 184.784 173.213 216.553 1.00 51.98  ? 171 ASP B O   1 
ATOM   4608  C CB  . ASP B 1 150 ? 186.551 174.046 213.938 1.00 51.98  ? 171 ASP B CB  1 
ATOM   4609  C CG  . ASP B 1 150 ? 186.275 175.354 214.653 1.00 51.98  ? 171 ASP B CG  1 
ATOM   4610  O OD1 . ASP B 1 150 ? 187.139 175.805 215.434 1.00 51.98  ? 171 ASP B OD1 1 
ATOM   4611  O OD2 . ASP B 1 150 ? 185.193 175.937 214.427 1.00 51.98  ? 171 ASP B OD2 1 
ATOM   4612  N N   . GLN B 1 151 ? 184.117 172.092 214.719 1.00 43.79  ? 172 GLN B N   1 
ATOM   4613  C CA  . GLN B 1 151 ? 182.721 172.052 215.135 1.00 43.79  ? 172 GLN B CA  1 
ATOM   4614  C C   . GLN B 1 151 ? 182.458 171.074 216.276 1.00 43.79  ? 172 GLN B C   1 
ATOM   4615  O O   . GLN B 1 151 ? 181.387 171.138 216.888 1.00 43.79  ? 172 GLN B O   1 
ATOM   4616  C CB  . GLN B 1 151 ? 181.829 171.704 213.940 1.00 43.79  ? 172 GLN B CB  1 
ATOM   4617  C CG  . GLN B 1 151 ? 181.728 172.813 212.904 1.00 43.79  ? 172 GLN B CG  1 
ATOM   4618  C CD  . GLN B 1 151 ? 180.726 172.502 211.809 1.00 43.79  ? 172 GLN B CD  1 
ATOM   4619  O OE1 . GLN B 1 151 ? 180.137 171.422 211.778 1.00 43.79  ? 172 GLN B OE1 1 
ATOM   4620  N NE2 . GLN B 1 151 ? 180.523 173.454 210.905 1.00 43.79  ? 172 GLN B NE2 1 
ATOM   4621  N N   . ILE B 1 152 ? 183.396 170.178 216.578 1.00 43.20  ? 173 ILE B N   1 
ATOM   4622  C CA  . ILE B 1 152 ? 183.277 169.312 217.747 1.00 43.20  ? 173 ILE B CA  1 
ATOM   4623  C C   . ILE B 1 152 ? 184.462 169.728 218.624 1.00 43.20  ? 173 ILE B C   1 
ATOM   4624  O O   . ILE B 1 152 ? 185.142 168.910 219.255 1.00 43.20  ? 173 ILE B O   1 
ATOM   4625  C CB  . ILE B 1 152 ? 183.231 167.802 217.387 1.00 43.20  ? 173 ILE B CB  1 
ATOM   4626  C CG1 . ILE B 1 152 ? 182.037 167.466 216.488 1.00 43.20  ? 173 ILE B CG1 1 
ATOM   4627  C CG2 . ILE B 1 152 ? 182.821 166.918 218.570 1.00 43.20  ? 173 ILE B CG2 1 
ATOM   4628  C CD1 . ILE B 1 152 ? 182.265 167.516 214.993 1.00 43.20  ? 173 ILE B CD1 1 
ATOM   4629  N N   . ASN B 1 153 ? 184.777 171.023 218.591 1.00 53.49  ? 174 ASN B N   1 
ATOM   4630  C CA  . ASN B 1 153 ? 185.639 171.618 219.603 1.00 53.49  ? 174 ASN B CA  1 
ATOM   4631  C C   . ASN B 1 153 ? 185.172 172.985 220.082 1.00 53.49  ? 174 ASN B C   1 
ATOM   4632  O O   . ASN B 1 153 ? 185.793 173.539 220.994 1.00 53.49  ? 174 ASN B O   1 
ATOM   4633  C CB  . ASN B 1 153 ? 187.088 171.728 219.098 1.00 53.49  ? 174 ASN B CB  1 
ATOM   4634  C CG  . ASN B 1 153 ? 187.903 170.481 219.392 1.00 53.49  ? 174 ASN B CG  1 
ATOM   4635  O OD1 . ASN B 1 153 ? 188.372 169.795 218.484 1.00 53.49  ? 174 ASN B OD1 1 
ATOM   4636  N ND2 . ASN B 1 153 ? 188.077 170.184 220.674 1.00 53.49  ? 174 ASN B ND2 1 
ATOM   4637  N N   . THR B 1 154 ? 184.105 173.544 219.511 1.00 52.90  ? 175 THR B N   1 
ATOM   4638  C CA  . THR B 1 154 ? 183.574 174.813 219.992 1.00 52.90  ? 175 THR B CA  1 
ATOM   4639  C C   . THR B 1 154 ? 182.057 174.862 220.072 1.00 52.90  ? 175 THR B C   1 
ATOM   4640  O O   . THR B 1 154 ? 181.529 175.826 220.633 1.00 52.90  ? 175 THR B O   1 
ATOM   4641  C CB  . THR B 1 154 ? 184.057 175.976 219.111 1.00 52.90  ? 175 THR B CB  1 
ATOM   4642  O OG1 . THR B 1 154 ? 183.753 177.217 219.756 1.00 52.90  ? 175 THR B OG1 1 
ATOM   4643  C CG2 . THR B 1 154 ? 183.370 175.950 217.753 1.00 52.90  ? 175 THR B CG2 1 
ATOM   4644  N N   . ASN B 1 155 ? 181.338 173.875 219.542 1.00 56.29  ? 176 ASN B N   1 
ATOM   4645  C CA  . ASN B 1 155 ? 179.881 173.891 219.528 1.00 56.29  ? 176 ASN B CA  1 
ATOM   4646  C C   . ASN B 1 155 ? 179.275 172.734 220.304 1.00 56.29  ? 176 ASN B C   1 
ATOM   4647  O O   . ASN B 1 155 ? 178.360 172.944 221.107 1.00 56.29  ? 176 ASN B O   1 
ATOM   4648  C CB  . ASN B 1 155 ? 179.373 173.875 218.077 1.00 56.29  ? 176 ASN B CB  1 
ATOM   4649  C CG  . ASN B 1 155 ? 177.903 173.525 217.979 1.00 56.29  ? 176 ASN B CG  1 
ATOM   4650  O OD1 . ASN B 1 155 ? 177.045 174.256 218.472 1.00 56.29  ? 176 ASN B OD1 1 
ATOM   4651  N ND2 . ASN B 1 155 ? 177.604 172.401 217.339 1.00 56.29  ? 176 ASN B ND2 1 
ATOM   4652  N N   . LEU B 1 156 ? 179.760 171.513 220.088 1.00 48.26  ? 177 LEU B N   1 
ATOM   4653  C CA  . LEU B 1 156 ? 179.197 170.342 220.746 1.00 48.26  ? 177 LEU B CA  1 
ATOM   4654  C C   . LEU B 1 156 ? 179.863 170.036 222.081 1.00 48.26  ? 177 LEU B C   1 
ATOM   4655  O O   . LEU B 1 156 ? 179.230 169.434 222.955 1.00 48.26  ? 177 LEU B O   1 
ATOM   4656  C CB  . LEU B 1 156 ? 179.307 169.126 219.823 1.00 48.26  ? 177 LEU B CB  1 
ATOM   4657  C CG  . LEU B 1 156 ? 178.232 168.050 219.964 1.00 48.26  ? 177 LEU B CG  1 
ATOM   4658  C CD1 . LEU B 1 156 ? 176.890 168.590 219.507 1.00 48.26  ? 177 LEU B CD1 1 
ATOM   4659  C CD2 . LEU B 1 156 ? 178.610 166.821 219.158 1.00 48.26  ? 177 LEU B CD2 1 
ATOM   4660  N N   . VAL B 1 157 ? 181.124 170.423 222.247 1.00 54.53  ? 178 VAL B N   1 
ATOM   4661  C CA  . VAL B 1 157 ? 181.878 170.222 223.487 1.00 54.53  ? 178 VAL B CA  1 
ATOM   4662  C C   . VAL B 1 157 ? 181.308 170.990 224.688 1.00 54.53  ? 178 VAL B C   1 
ATOM   4663  O O   . VAL B 1 157 ? 181.159 170.359 225.747 1.00 54.53  ? 178 VAL B O   1 
ATOM   4664  C CB  . VAL B 1 157 ? 183.374 170.523 223.255 1.00 54.53  ? 178 VAL B CB  1 
ATOM   4665  C CG1 . VAL B 1 157 ? 184.168 170.510 224.557 1.00 54.53  ? 178 VAL B CG1 1 
ATOM   4666  C CG2 . VAL B 1 157 ? 183.956 169.516 222.286 1.00 54.53  ? 178 VAL B CG2 1 
ATOM   4667  N N   . PRO B 1 158 ? 180.960 172.300 224.630 1.00 52.25  ? 179 PRO B N   1 
ATOM   4668  C CA  . PRO B 1 158 ? 180.415 172.941 225.848 1.00 52.25  ? 179 PRO B CA  1 
ATOM   4669  C C   . PRO B 1 158 ? 179.042 172.440 226.281 1.00 52.25  ? 179 PRO B C   1 
ATOM   4670  O O   . PRO B 1 158 ? 178.667 172.661 227.439 1.00 52.25  ? 179 PRO B O   1 
ATOM   4671  C CB  . PRO B 1 158 ? 180.359 174.429 225.472 1.00 52.25  ? 179 PRO B CB  1 
ATOM   4672  C CG  . PRO B 1 158 ? 181.358 174.576 224.412 1.00 52.25  ? 179 PRO B CG  1 
ATOM   4673  C CD  . PRO B 1 158 ? 181.166 173.344 223.600 1.00 52.25  ? 179 PRO B CD  1 
ATOM   4674  N N   . LYS B 1 159 ? 178.285 171.783 225.409 1.00 55.27  ? 180 LYS B N   1 
ATOM   4675  C CA  . LYS B 1 159 ? 177.041 171.129 225.815 1.00 55.27  ? 180 LYS B CA  1 
ATOM   4676  C C   . LYS B 1 159 ? 177.284 169.645 226.093 1.00 55.27  ? 180 LYS B C   1 
ATOM   4677  O O   . LYS B 1 159 ? 176.681 168.758 225.491 1.00 55.27  ? 180 LYS B O   1 
ATOM   4678  C CB  . LYS B 1 159 ? 175.962 171.329 224.755 1.00 55.27  ? 180 LYS B CB  1 
ATOM   4679  C CG  . LYS B 1 159 ? 176.469 171.320 223.327 1.00 55.27  ? 180 LYS B CG  1 
ATOM   4680  C CD  . LYS B 1 159 ? 175.396 171.802 222.364 1.00 55.27  ? 180 LYS B CD  1 
ATOM   4681  C CE  . LYS B 1 159 ? 175.289 173.318 222.367 1.00 55.27  ? 180 LYS B CE  1 
ATOM   4682  N NZ  . LYS B 1 159 ? 174.568 173.822 221.166 1.00 55.27  ? 180 LYS B NZ  1 
ATOM   4683  N N   . ILE B 1 160 ? 178.192 169.385 227.032 1.00 57.74  ? 181 ILE B N   1 
ATOM   4684  C CA  . ILE B 1 160 ? 178.522 168.011 227.391 1.00 57.74  ? 181 ILE B CA  1 
ATOM   4685  C C   . ILE B 1 160 ? 177.621 167.486 228.514 1.00 57.74  ? 181 ILE B C   1 
ATOM   4686  O O   . ILE B 1 160 ? 177.318 166.289 228.557 1.00 57.74  ? 181 ILE B O   1 
ATOM   4687  C CB  . ILE B 1 160 ? 180.025 167.913 227.745 1.00 57.74  ? 181 ILE B CB  1 
ATOM   4688  C CG1 . ILE B 1 160 ? 180.478 166.460 227.929 1.00 57.74  ? 181 ILE B CG1 1 
ATOM   4689  C CG2 . ILE B 1 160 ? 180.397 168.785 228.948 1.00 57.74  ? 181 ILE B CG2 1 
ATOM   4690  C CD1 . ILE B 1 160 ? 181.977 166.301 228.009 1.00 57.74  ? 181 ILE B CD1 1 
ATOM   4691  N N   . ASN B 1 161 ? 177.133 168.363 229.395 1.00 54.32  ? 182 ASN B N   1 
ATOM   4692  C CA  . ASN B 1 161 ? 176.268 167.954 230.490 1.00 54.32  ? 182 ASN B CA  1 
ATOM   4693  C C   . ASN B 1 161 ? 174.977 168.749 230.580 1.00 54.32  ? 182 ASN B C   1 
ATOM   4694  O O   . ASN B 1 161 ? 174.077 168.341 231.322 1.00 54.32  ? 182 ASN B O   1 
ATOM   4695  C CB  . ASN B 1 161 ? 177.010 168.059 231.832 1.00 54.32  ? 182 ASN B CB  1 
ATOM   4696  C CG  . ASN B 1 161 ? 177.979 166.915 232.052 1.00 54.32  ? 182 ASN B CG  1 
ATOM   4697  O OD1 . ASN B 1 161 ? 177.772 165.808 231.556 1.00 54.32  ? 182 ASN B OD1 1 
ATOM   4698  N ND2 . ASN B 1 161 ? 179.046 167.178 232.797 1.00 54.32  ? 182 ASN B ND2 1 
ATOM   4699  N N   . ILE B 1 162 ? 174.861 169.872 229.868 1.00 58.67  ? 183 ILE B N   1 
ATOM   4700  C CA  . ILE B 1 162 ? 173.604 170.612 229.831 1.00 58.67  ? 183 ILE B CA  1 
ATOM   4701  C C   . ILE B 1 162 ? 172.555 169.833 229.048 1.00 58.67  ? 183 ILE B C   1 
ATOM   4702  O O   . ILE B 1 162 ? 171.381 169.777 229.434 1.00 58.67  ? 183 ILE B O   1 
ATOM   4703  C CB  . ILE B 1 162 ? 173.837 172.014 229.238 1.00 58.67  ? 183 ILE B CB  1 
ATOM   4704  C CG1 . ILE B 1 162 ? 174.988 172.719 229.959 1.00 58.67  ? 183 ILE B CG1 1 
ATOM   4705  C CG2 . ILE B 1 162 ? 172.574 172.858 229.322 1.00 58.67  ? 183 ILE B CG2 1 
ATOM   4706  C CD1 . ILE B 1 162 ? 174.761 172.910 231.445 1.00 58.67  ? 183 ILE B CD1 1 
ATOM   4707  N N   . LEU B 1 163 ? 172.964 169.202 227.954 1.00 60.69  ? 184 LEU B N   1 
ATOM   4708  C CA  . LEU B 1 163 ? 172.072 168.468 227.074 1.00 60.69  ? 184 LEU B CA  1 
ATOM   4709  C C   . LEU B 1 163 ? 172.187 166.969 227.332 1.00 60.69  ? 184 LEU B C   1 
ATOM   4710  O O   . LEU B 1 163 ? 173.215 166.480 227.808 1.00 60.69  ? 184 LEU B O   1 
ATOM   4711  C CB  . LEU B 1 163 ? 172.399 168.787 225.614 1.00 60.69  ? 184 LEU B CB  1 
ATOM   4712  C CG  . LEU B 1 163 ? 171.317 168.619 224.552 1.00 60.69  ? 184 LEU B CG  1 
ATOM   4713  C CD1 . LEU B 1 163 ? 170.345 169.781 224.602 1.00 60.69  ? 184 LEU B CD1 1 
ATOM   4714  C CD2 . LEU B 1 163 ? 171.972 168.537 223.192 1.00 60.69  ? 184 LEU B CD2 1 
ATOM   4715  N N   . SER B 1 164 ? 171.111 166.246 227.027 1.00 60.93  ? 185 SER B N   1 
ATOM   4716  C CA  . SER B 1 164 ? 171.078 164.803 227.230 1.00 60.93  ? 185 SER B CA  1 
ATOM   4717  C C   . SER B 1 164 ? 171.974 164.090 226.223 1.00 60.93  ? 185 SER B C   1 
ATOM   4718  O O   . SER B 1 164 ? 172.154 164.545 225.091 1.00 60.93  ? 185 SER B O   1 
ATOM   4719  C CB  . SER B 1 164 ? 169.647 164.281 227.113 1.00 60.93  ? 185 SER B CB  1 
ATOM   4720  O OG  . SER B 1 164 ? 169.160 164.426 225.791 1.00 60.93  ? 185 SER B OG  1 
ATOM   4721  N N   . CYS B 1 165 ? 172.523 162.946 226.651 1.00 67.97  ? 186 CYS B N   1 
ATOM   4722  C CA  . CYS B 1 165 ? 173.537 162.236 225.870 1.00 67.97  ? 186 CYS B CA  1 
ATOM   4723  C C   . CYS B 1 165 ? 172.972 161.645 224.582 1.00 67.97  ? 186 CYS B C   1 
ATOM   4724  O O   . CYS B 1 165 ? 173.678 161.596 223.564 1.00 67.97  ? 186 CYS B O   1 
ATOM   4725  C CB  . CYS B 1 165 ? 174.169 161.134 226.720 1.00 67.97  ? 186 CYS B CB  1 
ATOM   4726  S SG  . CYS B 1 165 ? 175.021 161.721 228.205 1.00 67.97  ? 186 CYS B SG  1 
ATOM   4727  N N   . LYS B 1 166 ? 171.713 161.194 224.605 1.00 65.79  ? 187 LYS B N   1 
ATOM   4728  C CA  . LYS B 1 166 ? 171.086 160.691 223.386 1.00 65.79  ? 187 LYS B CA  1 
ATOM   4729  C C   . LYS B 1 166 ? 170.856 161.805 222.371 1.00 65.79  ? 187 LYS B C   1 
ATOM   4730  O O   . LYS B 1 166 ? 170.889 161.553 221.162 1.00 65.79  ? 187 LYS B O   1 
ATOM   4731  C CB  . LYS B 1 166 ? 169.774 159.976 223.720 1.00 65.79  ? 187 LYS B CB  1 
ATOM   4732  C CG  . LYS B 1 166 ? 168.737 160.829 224.437 1.00 65.79  ? 187 LYS B CG  1 
ATOM   4733  C CD  . LYS B 1 166 ? 167.479 160.033 224.742 1.00 65.79  ? 187 LYS B CD  1 
ATOM   4734  C CE  . LYS B 1 166 ? 166.481 160.859 225.536 1.00 65.79  ? 187 LYS B CE  1 
ATOM   4735  N NZ  . LYS B 1 166 ? 165.951 162.004 224.745 1.00 65.79  ? 187 LYS B NZ  1 
ATOM   4736  N N   . GLN B 1 167 ? 170.671 163.044 222.837 1.00 66.37  ? 188 GLN B N   1 
ATOM   4737  C CA  . GLN B 1 167 ? 170.542 164.165 221.913 1.00 66.37  ? 188 GLN B CA  1 
ATOM   4738  C C   . GLN B 1 167 ? 171.879 164.497 221.260 1.00 66.37  ? 188 GLN B C   1 
ATOM   4739  O O   . GLN B 1 167 ? 171.921 164.842 220.073 1.00 66.37  ? 188 GLN B O   1 
ATOM   4740  C CB  . GLN B 1 167 ? 169.970 165.383 222.638 1.00 66.37  ? 188 GLN B CB  1 
ATOM   4741  C CG  . GLN B 1 167 ? 169.277 166.416 221.742 1.00 66.37  ? 188 GLN B CG  1 
ATOM   4742  C CD  . GLN B 1 167 ? 167.963 165.931 221.140 1.00 66.37  ? 188 GLN B CD  1 
ATOM   4743  O OE1 . GLN B 1 167 ? 167.941 165.143 220.192 1.00 66.37  ? 188 GLN B OE1 1 
ATOM   4744  N NE2 . GLN B 1 167 ? 166.855 166.404 221.698 1.00 66.37  ? 188 GLN B NE2 1 
ATOM   4745  N N   . LEU B 1 168 ? 172.980 164.385 222.017 1.00 59.66  ? 189 LEU B N   1 
ATOM   4746  C CA  . LEU B 1 168 ? 174.313 164.519 221.428 1.00 59.66  ? 189 LEU B CA  1 
ATOM   4747  C C   . LEU B 1 168 ? 174.587 163.420 220.411 1.00 59.66  ? 189 LEU B C   1 
ATOM   4748  O O   . LEU B 1 168 ? 175.164 163.686 219.350 1.00 59.66  ? 189 LEU B O   1 
ATOM   4749  C CB  . LEU B 1 168 ? 175.397 164.503 222.509 1.00 59.66  ? 189 LEU B CB  1 
ATOM   4750  C CG  . LEU B 1 168 ? 175.825 165.790 223.222 1.00 59.66  ? 189 LEU B CG  1 
ATOM   4751  C CD1 . LEU B 1 168 ? 174.798 166.278 224.214 1.00 59.66  ? 189 LEU B CD1 1 
ATOM   4752  C CD2 . LEU B 1 168 ? 177.166 165.577 223.909 1.00 59.66  ? 189 LEU B CD2 1 
ATOM   4753  N N   . SER B 1 169 ? 174.174 162.184 220.716 1.00 61.08  ? 190 SER B N   1 
ATOM   4754  C CA  . SER B 1 169 ? 174.358 161.078 219.777 1.00 61.08  ? 190 SER B CA  1 
ATOM   4755  C C   . SER B 1 169 ? 173.542 161.279 218.502 1.00 61.08  ? 190 SER B C   1 
ATOM   4756  O O   . SER B 1 169 ? 174.042 161.036 217.396 1.00 61.08  ? 190 SER B O   1 
ATOM   4757  C CB  . SER B 1 169 ? 173.985 159.756 220.444 1.00 61.08  ? 190 SER B CB  1 
ATOM   4758  O OG  . SER B 1 169 ? 174.106 158.677 219.535 1.00 61.08  ? 190 SER B OG  1 
ATOM   4759  N N   . ASN B 1 170 ? 172.300 161.755 218.637 1.00 58.89  ? 191 ASN B N   1 
ATOM   4760  C CA  . ASN B 1 170 ? 171.454 161.998 217.471 1.00 58.89  ? 191 ASN B CA  1 
ATOM   4761  C C   . ASN B 1 170 ? 171.976 163.159 216.629 1.00 58.89  ? 191 ASN B C   1 
ATOM   4762  O O   . ASN B 1 170 ? 171.970 163.084 215.393 1.00 58.89  ? 191 ASN B O   1 
ATOM   4763  C CB  . ASN B 1 170 ? 170.017 162.260 217.920 1.00 58.89  ? 191 ASN B CB  1 
ATOM   4764  C CG  . ASN B 1 170 ? 169.007 162.030 216.812 1.00 58.89  ? 191 ASN B CG  1 
ATOM   4765  O OD1 . ASN B 1 170 ? 169.364 161.646 215.699 1.00 58.89  ? 191 ASN B OD1 1 
ATOM   4766  N ND2 . ASN B 1 170 ? 167.736 162.260 217.116 1.00 58.89  ? 191 ASN B ND2 1 
ATOM   4767  N N   . THR B 1 171 ? 172.441 164.234 217.279 1.00 50.74  ? 192 THR B N   1 
ATOM   4768  C CA  . THR B 1 171 ? 172.998 165.374 216.555 1.00 50.74  ? 192 THR B CA  1 
ATOM   4769  C C   . THR B 1 171 ? 174.294 164.997 215.844 1.00 50.74  ? 192 THR B C   1 
ATOM   4770  O O   . THR B 1 171 ? 174.525 165.413 214.699 1.00 50.74  ? 192 THR B O   1 
ATOM   4771  C CB  . THR B 1 171 ? 173.224 166.537 217.523 1.00 50.74  ? 192 THR B CB  1 
ATOM   4772  O OG1 . THR B 1 171 ? 172.013 166.798 218.242 1.00 50.74  ? 192 THR B OG1 1 
ATOM   4773  C CG2 . THR B 1 171 ? 173.627 167.800 216.775 1.00 50.74  ? 192 THR B CG2 1 
ATOM   4774  N N   . LEU B 1 172 ? 175.133 164.183 216.498 1.00 46.05  ? 193 LEU B N   1 
ATOM   4775  C CA  . LEU B 1 172 ? 176.354 163.685 215.875 1.00 46.05  ? 193 LEU B CA  1 
ATOM   4776  C C   . LEU B 1 172 ? 176.047 162.789 214.683 1.00 46.05  ? 193 LEU B C   1 
ATOM   4777  O O   . LEU B 1 172 ? 176.730 162.869 213.657 1.00 46.05  ? 193 LEU B O   1 
ATOM   4778  C CB  . LEU B 1 172 ? 177.194 162.933 216.906 1.00 46.05  ? 193 LEU B CB  1 
ATOM   4779  C CG  . LEU B 1 172 ? 178.627 162.574 216.515 1.00 46.05  ? 193 LEU B CG  1 
ATOM   4780  C CD1 . LEU B 1 172 ? 179.355 163.777 215.940 1.00 46.05  ? 193 LEU B CD1 1 
ATOM   4781  C CD2 . LEU B 1 172 ? 179.376 162.009 217.713 1.00 46.05  ? 193 LEU B CD2 1 
ATOM   4782  N N   . ASN B 1 173 ? 175.010 161.948 214.793 1.00 42.82  ? 194 ASN B N   1 
ATOM   4783  C CA  . ASN B 1 173 ? 174.617 161.097 213.672 1.00 42.82  ? 194 ASN B CA  1 
ATOM   4784  C C   . ASN B 1 173 ? 174.088 161.913 212.497 1.00 42.82  ? 194 ASN B C   1 
ATOM   4785  O O   . ASN B 1 173 ? 174.416 161.618 211.343 1.00 42.82  ? 194 ASN B O   1 
ATOM   4786  C CB  . ASN B 1 173 ? 173.576 160.074 214.128 1.00 42.82  ? 194 ASN B CB  1 
ATOM   4787  C CG  . ASN B 1 173 ? 174.201 158.876 214.811 1.00 42.82  ? 194 ASN B CG  1 
ATOM   4788  O OD1 . ASN B 1 173 ? 175.216 158.348 214.356 1.00 42.82  ? 194 ASN B OD1 1 
ATOM   4789  N ND2 . ASN B 1 173 ? 173.596 158.436 215.907 1.00 42.82  ? 194 ASN B ND2 1 
ATOM   4790  N N   . ILE B 1 174 ? 173.289 162.952 212.772 1.00 40.45  ? 195 ILE B N   1 
ATOM   4791  C CA  . ILE B 1 174 ? 172.766 163.810 211.707 1.00 40.45  ? 195 ILE B CA  1 
ATOM   4792  C C   . ILE B 1 174 ? 173.896 164.566 211.008 1.00 40.45  ? 195 ILE B C   1 
ATOM   4793  O O   . ILE B 1 174 ? 173.954 164.618 209.768 1.00 40.45  ? 195 ILE B O   1 
ATOM   4794  C CB  . ILE B 1 174 ? 171.695 164.764 212.275 1.00 40.45  ? 195 ILE B CB  1 
ATOM   4795  C CG1 . ILE B 1 174 ? 170.421 163.998 212.647 1.00 40.45  ? 195 ILE B CG1 1 
ATOM   4796  C CG2 . ILE B 1 174 ? 171.354 165.874 211.290 1.00 40.45  ? 195 ILE B CG2 1 
ATOM   4797  C CD1 . ILE B 1 174 ? 169.908 163.068 211.565 1.00 40.45  ? 195 ILE B CD1 1 
ATOM   4798  N N   . MET B 1 175 ? 174.838 165.113 211.786 1.00 31.35  ? 196 MET B N   1 
ATOM   4799  C CA  . MET B 1 175 ? 175.945 165.866 211.201 1.00 31.35  ? 196 MET B CA  1 
ATOM   4800  C C   . MET B 1 175 ? 176.899 164.952 210.431 1.00 31.35  ? 196 MET B C   1 
ATOM   4801  O O   . MET B 1 175 ? 177.391 165.325 209.358 1.00 31.35  ? 196 MET B O   1 
ATOM   4802  C CB  . MET B 1 175 ? 176.670 166.647 212.303 1.00 31.35  ? 196 MET B CB  1 
ATOM   4803  C CG  . MET B 1 175 ? 178.061 167.153 211.959 1.00 31.35  ? 196 MET B CG  1 
ATOM   4804  S SD  . MET B 1 175 ? 178.749 168.207 213.251 1.00 31.35  ? 196 MET B SD  1 
ATOM   4805  C CE  . MET B 1 175 ? 178.334 167.270 214.719 1.00 31.35  ? 196 MET B CE  1 
ATOM   4806  N N   . LEU B 1 176 ? 177.120 163.727 210.922 1.00 28.51  ? 197 LEU B N   1 
ATOM   4807  C CA  . LEU B 1 176 ? 177.974 162.787 210.203 1.00 28.51  ? 197 LEU B CA  1 
ATOM   4808  C C   . LEU B 1 176 ? 177.317 162.260 208.933 1.00 28.51  ? 197 LEU B C   1 
ATOM   4809  O O   . LEU B 1 176 ? 178.015 162.022 207.945 1.00 28.51  ? 197 LEU B O   1 
ATOM   4810  C CB  . LEU B 1 176 ? 178.378 161.628 211.112 1.00 28.51  ? 197 LEU B CB  1 
ATOM   4811  C CG  . LEU B 1 176 ? 179.507 161.931 212.098 1.00 28.51  ? 197 LEU B CG  1 
ATOM   4812  C CD1 . LEU B 1 176 ? 179.709 160.774 213.062 1.00 28.51  ? 197 LEU B CD1 1 
ATOM   4813  C CD2 . LEU B 1 176 ? 180.792 162.243 211.352 1.00 28.51  ? 197 LEU B CD2 1 
ATOM   4814  N N   . LEU B 1 177 ? 175.992 162.066 208.932 1.00 24.05  ? 198 LEU B N   1 
ATOM   4815  C CA  . LEU B 1 177 ? 175.305 161.694 207.695 1.00 24.05  ? 198 LEU B CA  1 
ATOM   4816  C C   . LEU B 1 177 ? 175.346 162.820 206.665 1.00 24.05  ? 198 LEU B C   1 
ATOM   4817  O O   . LEU B 1 177 ? 175.536 162.562 205.466 1.00 24.05  ? 198 LEU B O   1 
ATOM   4818  C CB  . LEU B 1 177 ? 173.862 161.278 207.988 1.00 24.05  ? 198 LEU B CB  1 
ATOM   4819  C CG  . LEU B 1 177 ? 173.550 159.786 208.176 1.00 24.05  ? 198 LEU B CG  1 
ATOM   4820  C CD1 . LEU B 1 177 ? 173.772 159.071 206.860 1.00 24.05  ? 198 LEU B CD1 1 
ATOM   4821  C CD2 . LEU B 1 177 ? 174.363 159.106 209.267 1.00 24.05  ? 198 LEU B CD2 1 
ATOM   4822  N N   . GLN B 1 178 ? 175.190 164.072 207.116 1.00 23.21  ? 199 GLN B N   1 
ATOM   4823  C CA  . GLN B 1 178 ? 175.327 165.215 206.214 1.00 23.21  ? 199 GLN B CA  1 
ATOM   4824  C C   . GLN B 1 178 ? 176.742 165.313 205.650 1.00 23.21  ? 199 GLN B C   1 
ATOM   4825  O O   . GLN B 1 178 ? 176.930 165.564 204.450 1.00 23.21  ? 199 GLN B O   1 
ATOM   4826  C CB  . GLN B 1 178 ? 174.944 166.502 206.947 1.00 23.21  ? 199 GLN B CB  1 
ATOM   4827  C CG  . GLN B 1 178 ? 174.741 167.710 206.050 1.00 23.21  ? 199 GLN B CG  1 
ATOM   4828  C CD  . GLN B 1 178 ? 175.978 168.578 205.953 1.00 23.21  ? 199 GLN B CD  1 
ATOM   4829  O OE1 . GLN B 1 178 ? 176.787 168.629 206.879 1.00 23.21  ? 199 GLN B OE1 1 
ATOM   4830  N NE2 . GLN B 1 178 ? 176.130 169.272 204.832 1.00 23.21  ? 199 GLN B NE2 1 
ATOM   4831  N N   . TYR B 1 179 ? 177.750 165.064 206.487 1.00 21.53  ? 200 TYR B N   1 
ATOM   4832  C CA  . TYR B 1 179 ? 179.124 165.114 206.002 1.00 21.53  ? 200 TYR B CA  1 
ATOM   4833  C C   . TYR B 1 179 ? 179.443 163.944 205.077 1.00 21.53  ? 200 TYR B C   1 
ATOM   4834  O O   . TYR B 1 179 ? 180.197 164.122 204.119 1.00 21.53  ? 200 TYR B O   1 
ATOM   4835  C CB  . TYR B 1 179 ? 180.097 165.170 207.178 1.00 21.53  ? 200 TYR B CB  1 
ATOM   4836  C CG  . TYR B 1 179 ? 181.527 165.430 206.768 1.00 21.53  ? 200 TYR B CG  1 
ATOM   4837  C CD1 . TYR B 1 179 ? 181.827 166.404 205.824 1.00 21.53  ? 200 TYR B CD1 1 
ATOM   4838  C CD2 . TYR B 1 179 ? 182.580 164.742 207.360 1.00 21.53  ? 200 TYR B CD2 1 
ATOM   4839  C CE1 . TYR B 1 179 ? 183.132 166.661 205.453 1.00 21.53  ? 200 TYR B CE1 1 
ATOM   4840  C CE2 . TYR B 1 179 ? 183.891 164.996 207.000 1.00 21.53  ? 200 TYR B CE2 1 
ATOM   4841  C CZ  . TYR B 1 179 ? 184.158 165.956 206.044 1.00 21.53  ? 200 TYR B CZ  1 
ATOM   4842  O OH  . TYR B 1 179 ? 185.457 166.216 205.675 1.00 21.53  ? 200 TYR B OH  1 
ATOM   4843  N N   . TYR B 1 180 ? 178.864 162.762 205.323 1.00 17.18  ? 201 TYR B N   1 
ATOM   4844  C CA  . TYR B 1 180 ? 179.039 161.638 204.406 1.00 17.18  ? 201 TYR B CA  1 
ATOM   4845  C C   . TYR B 1 180 ? 178.403 161.931 203.054 1.00 17.18  ? 201 TYR B C   1 
ATOM   4846  O O   . TYR B 1 180 ? 178.946 161.549 202.008 1.00 17.18  ? 201 TYR B O   1 
ATOM   4847  C CB  . TYR B 1 180 ? 178.452 160.364 205.010 1.00 17.18  ? 201 TYR B CB  1 
ATOM   4848  C CG  . TYR B 1 180 ? 178.364 159.219 204.030 1.00 17.18  ? 201 TYR B CG  1 
ATOM   4849  C CD1 . TYR B 1 180 ? 179.513 158.584 203.577 1.00 17.18  ? 201 TYR B CD1 1 
ATOM   4850  C CD2 . TYR B 1 180 ? 177.135 158.772 203.557 1.00 17.18  ? 201 TYR B CD2 1 
ATOM   4851  C CE1 . TYR B 1 180 ? 179.443 157.538 202.678 1.00 17.18  ? 201 TYR B CE1 1 
ATOM   4852  C CE2 . TYR B 1 180 ? 177.055 157.729 202.657 1.00 17.18  ? 201 TYR B CE2 1 
ATOM   4853  C CZ  . TYR B 1 180 ? 178.212 157.114 202.224 1.00 17.18  ? 201 TYR B CZ  1 
ATOM   4854  O OH  . TYR B 1 180 ? 178.133 156.074 201.328 1.00 17.18  ? 201 TYR B OH  1 
ATOM   4855  N N   . SER B 1 181 ? 177.274 162.644 203.055 1.00 14.19  ? 202 SER B N   1 
ATOM   4856  C CA  . SER B 1 181 ? 176.725 163.150 201.802 1.00 14.19  ? 202 SER B CA  1 
ATOM   4857  C C   . SER B 1 181 ? 177.642 164.185 201.153 1.00 14.19  ? 202 SER B C   1 
ATOM   4858  O O   . SER B 1 181 ? 177.626 164.340 199.927 1.00 14.19  ? 202 SER B O   1 
ATOM   4859  C CB  . SER B 1 181 ? 175.340 163.748 202.036 1.00 14.19  ? 202 SER B CB  1 
ATOM   4860  O OG  . SER B 1 181 ? 174.899 164.455 200.893 1.00 14.19  ? 202 SER B OG  1 
ATOM   4861  N N   . GLN B 1 182 ? 178.434 164.911 201.951 1.00 16.01  ? 203 GLN B N   1 
ATOM   4862  C CA  . GLN B 1 182 ? 179.384 165.861 201.366 1.00 16.01  ? 203 GLN B CA  1 
ATOM   4863  C C   . GLN B 1 182 ? 180.588 165.164 200.723 1.00 16.01  ? 203 GLN B C   1 
ATOM   4864  O O   . GLN B 1 182 ? 181.083 165.626 199.687 1.00 16.01  ? 203 GLN B O   1 
ATOM   4865  C CB  . GLN B 1 182 ? 179.844 166.878 202.409 1.00 16.01  ? 203 GLN B CB  1 
ATOM   4866  C CG  . GLN B 1 182 ? 178.747 167.813 202.867 1.00 16.01  ? 203 GLN B CG  1 
ATOM   4867  C CD  . GLN B 1 182 ? 178.707 169.094 202.061 1.00 16.01  ? 203 GLN B CD  1 
ATOM   4868  O OE1 . GLN B 1 182 ? 178.568 169.068 200.839 1.00 16.01  ? 203 GLN B OE1 1 
ATOM   4869  N NE2 . GLN B 1 182 ? 178.823 170.225 202.744 1.00 16.01  ? 203 GLN B NE2 1 
ATOM   4870  N N   . ILE B 1 183 ? 181.107 164.090 201.337 1.00 11.92  ? 204 ILE B N   1 
ATOM   4871  C CA  . ILE B 1 183 ? 182.117 163.267 200.650 1.00 11.92  ? 204 ILE B CA  1 
ATOM   4872  C C   . ILE B 1 183 ? 181.540 162.615 199.395 1.00 11.92  ? 204 ILE B C   1 
ATOM   4873  O O   . ILE B 1 183 ? 182.179 162.627 198.333 1.00 11.92  ? 204 ILE B O   1 
ATOM   4874  C CB  . ILE B 1 183 ? 182.798 162.231 201.584 1.00 11.92  ? 204 ILE B CB  1 
ATOM   4875  C CG1 . ILE B 1 183 ? 183.752 162.874 202.602 1.00 11.92  ? 204 ILE B CG1 1 
ATOM   4876  C CG2 . ILE B 1 183 ? 183.542 161.134 200.823 1.00 11.92  ? 204 ILE B CG2 1 
ATOM   4877  C CD1 . ILE B 1 183 ? 183.230 163.250 203.906 1.00 11.92  ? 204 ILE B CD1 1 
ATOM   4878  N N   . LEU B 1 184 ? 180.300 162.109 199.458 1.00 19.29  ? 205 LEU B N   1 
ATOM   4879  C CA  . LEU B 1 184 ? 179.741 161.449 198.260 1.00 19.29  ? 205 LEU B CA  1 
ATOM   4880  C C   . LEU B 1 184 ? 179.404 162.420 197.076 1.00 19.29  ? 205 LEU B C   1 
ATOM   4881  O O   . LEU B 1 184 ? 178.825 161.942 196.091 1.00 19.29  ? 205 LEU B O   1 
ATOM   4882  C CB  . LEU B 1 184 ? 178.491 160.650 198.626 1.00 19.29  ? 205 LEU B CB  1 
ATOM   4883  C CG  . LEU B 1 184 ? 178.686 159.149 198.847 1.00 19.29  ? 205 LEU B CG  1 
ATOM   4884  C CD1 . LEU B 1 184 ? 177.342 158.474 199.052 1.00 19.29  ? 205 LEU B CD1 1 
ATOM   4885  C CD2 . LEU B 1 184 ? 179.429 158.521 197.679 1.00 19.29  ? 205 LEU B CD2 1 
ATOM   4886  N N   . THR B 1 185 ? 179.731 163.711 197.123 1.00 19.53  ? 206 THR B N   1 
ATOM   4887  C CA  . THR B 1 185 ? 179.588 164.618 195.993 1.00 19.53  ? 206 THR B CA  1 
ATOM   4888  C C   . THR B 1 185 ? 180.925 164.975 195.360 1.00 19.53  ? 206 THR B C   1 
ATOM   4889  O O   . THR B 1 185 ? 181.071 164.887 194.136 1.00 19.53  ? 206 THR B O   1 
ATOM   4890  C CB  . THR B 1 185 ? 178.860 165.896 196.438 1.00 19.53  ? 206 THR B CB  1 
ATOM   4891  O OG1 . THR B 1 185 ? 177.585 165.550 196.991 1.00 19.53  ? 206 THR B OG1 1 
ATOM   4892  C CG2 . THR B 1 185 ? 178.647 166.834 195.262 1.00 19.53  ? 206 THR B CG2 1 
ATOM   4893  N N   . VAL B 1 186 ? 181.913 165.375 196.168 1.00 18.82  ? 207 VAL B N   1 
ATOM   4894  C CA  . VAL B 1 186 ? 183.208 165.785 195.626 1.00 18.82  ? 207 VAL B CA  1 
ATOM   4895  C C   . VAL B 1 186 ? 184.000 164.585 195.098 1.00 18.82  ? 207 VAL B C   1 
ATOM   4896  O O   . VAL B 1 186 ? 184.591 164.651 194.013 1.00 18.82  ? 207 VAL B O   1 
ATOM   4897  C CB  . VAL B 1 186 ? 183.985 166.625 196.666 1.00 18.82  ? 207 VAL B CB  1 
ATOM   4898  C CG1 . VAL B 1 186 ? 184.158 165.903 197.997 1.00 18.82  ? 207 VAL B CG1 1 
ATOM   4899  C CG2 . VAL B 1 186 ? 185.349 167.023 196.120 1.00 18.82  ? 207 VAL B CG2 1 
ATOM   4900  N N   . PHE B 1 187 ? 183.992 163.462 195.813 1.00 24.13  ? 208 PHE B N   1 
ATOM   4901  C CA  . PHE B 1 187 ? 184.662 162.256 195.324 1.00 24.13  ? 208 PHE B CA  1 
ATOM   4902  C C   . PHE B 1 187 ? 183.695 161.356 194.560 1.00 24.13  ? 208 PHE B C   1 
ATOM   4903  O O   . PHE B 1 187 ? 183.579 160.160 194.821 1.00 24.13  ? 208 PHE B O   1 
ATOM   4904  C CB  . PHE B 1 187 ? 185.315 161.511 196.482 1.00 24.13  ? 208 PHE B CB  1 
ATOM   4905  C CG  . PHE B 1 187 ? 186.388 162.297 197.180 1.00 24.13  ? 208 PHE B CG  1 
ATOM   4906  C CD1 . PHE B 1 187 ? 187.644 162.436 196.610 1.00 24.13  ? 208 PHE B CD1 1 
ATOM   4907  C CD2 . PHE B 1 187 ? 186.146 162.889 198.409 1.00 24.13  ? 208 PHE B CD2 1 
ATOM   4908  C CE1 . PHE B 1 187 ? 188.638 163.158 197.251 1.00 24.13  ? 208 PHE B CE1 1 
ATOM   4909  C CE2 . PHE B 1 187 ? 187.136 163.613 199.056 1.00 24.13  ? 208 PHE B CE2 1 
ATOM   4910  C CZ  . PHE B 1 187 ? 188.382 163.746 198.475 1.00 24.13  ? 208 PHE B CZ  1 
ATOM   4911  N N   . GLY B 1 188 ? 182.991 161.947 193.599 1.00 33.59  ? 209 GLY B N   1 
ATOM   4912  C CA  . GLY B 1 188 ? 182.059 161.231 192.761 1.00 33.59  ? 209 GLY B CA  1 
ATOM   4913  C C   . GLY B 1 188 ? 182.685 160.642 191.511 1.00 33.59  ? 209 GLY B C   1 
ATOM   4914  O O   . GLY B 1 188 ? 182.655 159.426 191.300 1.00 33.59  ? 209 GLY B O   1 
ATOM   4915  N N   . PRO B 1 189 ? 183.255 161.492 190.644 1.00 35.64  ? 210 PRO B N   1 
ATOM   4916  C CA  . PRO B 1 189 ? 183.978 160.964 189.474 1.00 35.64  ? 210 PRO B CA  1 
ATOM   4917  C C   . PRO B 1 189 ? 185.270 160.233 189.808 1.00 35.64  ? 210 PRO B C   1 
ATOM   4918  O O   . PRO B 1 189 ? 185.792 159.523 188.939 1.00 35.64  ? 210 PRO B O   1 
ATOM   4919  C CB  . PRO B 1 189 ? 184.256 162.222 188.642 1.00 35.64  ? 210 PRO B CB  1 
ATOM   4920  C CG  . PRO B 1 189 ? 183.139 163.129 188.989 1.00 35.64  ? 210 PRO B CG  1 
ATOM   4921  C CD  . PRO B 1 189 ? 182.925 162.918 190.460 1.00 35.64  ? 210 PRO B CD  1 
ATOM   4922  N N   . ASN B 1 190 ? 185.809 160.384 191.020 1.00 37.82  ? 211 ASN B N   1 
ATOM   4923  C CA  . ASN B 1 190 ? 187.036 159.683 191.382 1.00 37.82  ? 211 ASN B CA  1 
ATOM   4924  C C   . ASN B 1 190 ? 186.824 158.189 191.590 1.00 37.82  ? 211 ASN B C   1 
ATOM   4925  O O   . ASN B 1 190 ? 187.789 157.427 191.500 1.00 37.82  ? 211 ASN B O   1 
ATOM   4926  C CB  . ASN B 1 190 ? 187.645 160.296 192.644 1.00 37.82  ? 211 ASN B CB  1 
ATOM   4927  C CG  . ASN B 1 190 ? 188.083 161.731 192.443 1.00 37.82  ? 211 ASN B CG  1 
ATOM   4928  O OD1 . ASN B 1 190 ? 187.534 162.651 193.047 1.00 37.82  ? 211 ASN B OD1 1 
ATOM   4929  N ND2 . ASN B 1 190 ? 189.084 161.929 191.594 1.00 37.82  ? 211 ASN B ND2 1 
ATOM   4930  N N   . LEU B 1 191 ? 185.591 157.748 191.852 1.00 40.66  ? 212 LEU B N   1 
ATOM   4931  C CA  . LEU B 1 191 ? 185.352 156.338 192.143 1.00 40.66  ? 212 LEU B CA  1 
ATOM   4932  C C   . LEU B 1 191 ? 185.440 155.449 190.907 1.00 40.66  ? 212 LEU B C   1 
ATOM   4933  O O   . LEU B 1 191 ? 185.523 154.225 191.051 1.00 40.66  ? 212 LEU B O   1 
ATOM   4934  C CB  . LEU B 1 191 ? 183.988 156.161 192.808 1.00 40.66  ? 212 LEU B CB  1 
ATOM   4935  C CG  . LEU B 1 191 ? 183.800 156.830 194.170 1.00 40.66  ? 212 LEU B CG  1 
ATOM   4936  C CD1 . LEU B 1 191 ? 182.325 157.069 194.448 1.00 40.66  ? 212 LEU B CD1 1 
ATOM   4937  C CD2 . LEU B 1 191 ? 184.426 155.991 195.271 1.00 40.66  ? 212 LEU B CD2 1 
ATOM   4938  N N   . ARG B 1 192 ? 185.407 156.029 189.705 1.00 50.18  ? 213 ARG B N   1 
ATOM   4939  C CA  . ARG B 1 192 ? 185.561 155.237 188.488 1.00 50.18  ? 213 ARG B CA  1 
ATOM   4940  C C   . ARG B 1 192 ? 186.984 154.705 188.349 1.00 50.18  ? 213 ARG B C   1 
ATOM   4941  O O   . ARG B 1 192 ? 187.191 153.507 188.122 1.00 50.18  ? 213 ARG B O   1 
ATOM   4942  C CB  . ARG B 1 192 ? 185.180 156.079 187.271 1.00 50.18  ? 213 ARG B CB  1 
ATOM   4943  C CG  . ARG B 1 192 ? 185.481 155.421 185.932 1.00 50.18  ? 213 ARG B CG  1 
ATOM   4944  C CD  . ARG B 1 192 ? 184.761 156.086 184.752 1.00 50.18  ? 213 ARG B CD  1 
ATOM   4945  N NE  . ARG B 1 192 ? 185.103 157.494 184.564 1.00 50.18  ? 213 ARG B NE  1 
ATOM   4946  C CZ  . ARG B 1 192 ? 184.350 158.515 184.951 1.00 50.18  ? 213 ARG B CZ  1 
ATOM   4947  N NH1 . ARG B 1 192 ? 183.190 158.327 185.559 1.00 50.18  ? 213 ARG B NH1 1 
ATOM   4948  N NH2 . ARG B 1 192 ? 184.772 159.756 184.726 1.00 50.18  ? 213 ARG B NH2 1 
ATOM   4949  N N   . ASP B 1 193 ? 187.975 155.583 188.496 1.00 51.83  ? 214 ASP B N   1 
ATOM   4950  C CA  . ASP B 1 193 ? 189.393 155.257 188.391 1.00 51.83  ? 214 ASP B CA  1 
ATOM   4951  C C   . ASP B 1 193 ? 190.232 156.307 189.121 1.00 51.83  ? 214 ASP B C   1 
ATOM   4952  O O   . ASP B 1 193 ? 190.644 157.314 188.530 1.00 51.83  ? 214 ASP B O   1 
ATOM   4953  C CB  . ASP B 1 193 ? 189.795 155.087 186.917 1.00 51.83  ? 214 ASP B CB  1 
ATOM   4954  C CG  . ASP B 1 193 ? 189.308 156.224 186.026 1.00 51.83  ? 214 ASP B CG  1 
ATOM   4955  O OD1 . ASP B 1 193 ? 188.561 157.096 186.516 1.00 51.83  ? 214 ASP B OD1 1 
ATOM   4956  O OD2 . ASP B 1 193 ? 189.674 156.239 184.832 1.00 51.83  ? 214 ASP B OD2 1 
ATOM   4957  N N   . PRO B 1 194 ? 190.521 156.100 190.426 1.00 40.95  ? 215 PRO B N   1 
ATOM   4958  C CA  . PRO B 1 194 ? 191.103 157.149 191.277 1.00 40.95  ? 215 PRO B CA  1 
ATOM   4959  C C   . PRO B 1 194 ? 192.610 157.352 191.133 1.00 40.95  ? 215 PRO B C   1 
ATOM   4960  O O   . PRO B 1 194 ? 193.331 157.502 192.120 1.00 40.95  ? 215 PRO B O   1 
ATOM   4961  C CB  . PRO B 1 194 ? 190.752 156.664 192.686 1.00 40.95  ? 215 PRO B CB  1 
ATOM   4962  C CG  . PRO B 1 194 ? 190.792 155.187 192.558 1.00 40.95  ? 215 PRO B CG  1 
ATOM   4963  C CD  . PRO B 1 194 ? 190.252 154.869 191.189 1.00 40.95  ? 215 PRO B CD  1 
ATOM   4964  N N   . ALA B 1 195 ? 193.088 157.372 189.894 1.00 33.25  ? 216 ALA B N   1 
ATOM   4965  C CA  . ALA B 1 195 ? 194.474 157.730 189.618 1.00 33.25  ? 216 ALA B CA  1 
ATOM   4966  C C   . ALA B 1 195 ? 194.625 158.725 188.484 1.00 33.25  ? 216 ALA B C   1 
ATOM   4967  O O   . ALA B 1 195 ? 195.656 159.403 188.423 1.00 33.25  ? 216 ALA B O   1 
ATOM   4968  C CB  . ALA B 1 195 ? 195.302 156.481 189.295 1.00 33.25  ? 216 ALA B CB  1 
ATOM   4969  N N   . THR B 1 196 ? 193.644 158.849 187.591 1.00 44.08  ? 217 THR B N   1 
ATOM   4970  C CA  . THR B 1 196 ? 193.730 159.726 186.436 1.00 44.08  ? 217 THR B CA  1 
ATOM   4971  C C   . THR B 1 196 ? 192.762 160.898 186.494 1.00 44.08  ? 217 THR B C   1 
ATOM   4972  O O   . THR B 1 196 ? 192.950 161.868 185.753 1.00 44.08  ? 217 THR B O   1 
ATOM   4973  C CB  . THR B 1 196 ? 193.465 158.930 185.151 1.00 44.08  ? 217 THR B CB  1 
ATOM   4974  O OG1 . THR B 1 196 ? 192.070 158.615 185.067 1.00 44.08  ? 217 THR B OG1 1 
ATOM   4975  C CG2 . THR B 1 196 ? 194.256 157.633 185.163 1.00 44.08  ? 217 THR B CG2 1 
ATOM   4976  N N   . VAL B 1 197 ? 191.745 160.837 187.343 1.00 39.38  ? 218 VAL B N   1 
ATOM   4977  C CA  . VAL B 1 197 ? 190.744 161.894 187.461 1.00 39.38  ? 218 VAL B CA  1 
ATOM   4978  C C   . VAL B 1 197 ? 191.181 162.831 188.580 1.00 39.38  ? 218 VAL B C   1 
ATOM   4979  O O   . VAL B 1 197 ? 191.288 162.388 189.734 1.00 39.38  ? 218 VAL B O   1 
ATOM   4980  C CB  . VAL B 1 197 ? 189.347 161.321 187.737 1.00 39.38  ? 218 VAL B CB  1 
ATOM   4981  C CG1 . VAL B 1 197 ? 188.363 162.443 188.025 1.00 39.38  ? 218 VAL B CG1 1 
ATOM   4982  C CG2 . VAL B 1 197 ? 188.878 160.485 186.558 1.00 39.38  ? 218 VAL B CG2 1 
ATOM   4983  N N   . PRO B 1 198 ? 191.442 164.105 188.298 1.00 28.81  ? 219 PRO B N   1 
ATOM   4984  C CA  . PRO B 1 198 ? 191.925 165.009 189.347 1.00 28.81  ? 219 PRO B CA  1 
ATOM   4985  C C   . PRO B 1 198 ? 190.798 165.685 190.111 1.00 28.81  ? 219 PRO B C   1 
ATOM   4986  O O   . PRO B 1 198 ? 189.620 165.487 189.798 1.00 28.81  ? 219 PRO B O   1 
ATOM   4987  C CB  . PRO B 1 198 ? 192.756 166.020 188.558 1.00 28.81  ? 219 PRO B CB  1 
ATOM   4988  C CG  . PRO B 1 198 ? 192.035 166.121 187.255 1.00 28.81  ? 219 PRO B CG  1 
ATOM   4989  C CD  . PRO B 1 198 ? 191.451 164.751 186.973 1.00 28.81  ? 219 PRO B CD  1 
ATOM   4990  N N   . VAL B 1 199 ? 191.150 166.486 191.113 1.00 24.07  ? 220 VAL B N   1 
ATOM   4991  C CA  . VAL B 1 199 ? 190.185 167.143 191.988 1.00 24.07  ? 220 VAL B CA  1 
ATOM   4992  C C   . VAL B 1 199 ? 190.416 168.647 191.909 1.00 24.07  ? 220 VAL B C   1 
ATOM   4993  O O   . VAL B 1 199 ? 191.527 169.123 192.173 1.00 24.07  ? 220 VAL B O   1 
ATOM   4994  C CB  . VAL B 1 199 ? 190.303 166.641 193.437 1.00 24.07  ? 220 VAL B CB  1 
ATOM   4995  C CG1 . VAL B 1 199 ? 189.499 167.516 194.381 1.00 24.07  ? 220 VAL B CG1 1 
ATOM   4996  C CG2 . VAL B 1 199 ? 189.849 165.194 193.537 1.00 24.07  ? 220 VAL B CG2 1 
ATOM   4997  N N   . SER B 1 200 ? 189.374 169.389 191.542 1.00 22.31  ? 221 SER B N   1 
ATOM   4998  C CA  . SER B 1 200 ? 189.440 170.843 191.533 1.00 22.31  ? 221 SER B CA  1 
ATOM   4999  C C   . SER B 1 200 ? 189.427 171.382 192.959 1.00 22.31  ? 221 SER B C   1 
ATOM   5000  O O   . SER B 1 200 ? 188.856 170.774 193.869 1.00 22.31  ? 221 SER B O   1 
ATOM   5001  C CB  . SER B 1 200 ? 188.273 171.432 190.742 1.00 22.31  ? 221 SER B CB  1 
ATOM   5002  O OG  . SER B 1 200 ? 188.338 171.052 189.379 1.00 22.31  ? 221 SER B OG  1 
ATOM   5003  N N   . ILE B 1 201 ? 190.063 172.540 193.148 1.00 18.60  ? 222 ILE B N   1 
ATOM   5004  C CA  . ILE B 1 201 ? 190.199 173.087 194.494 1.00 18.60  ? 222 ILE B CA  1 
ATOM   5005  C C   . ILE B 1 201 ? 188.901 173.722 194.993 1.00 18.60  ? 222 ILE B C   1 
ATOM   5006  O O   . ILE B 1 201 ? 188.713 173.844 196.209 1.00 18.60  ? 222 ILE B O   1 
ATOM   5007  C CB  . ILE B 1 201 ? 191.388 174.069 194.543 1.00 18.60  ? 222 ILE B CB  1 
ATOM   5008  C CG1 . ILE B 1 201 ? 191.949 174.186 195.962 1.00 18.60  ? 222 ILE B CG1 1 
ATOM   5009  C CG2 . ILE B 1 201 ? 191.016 175.438 194.001 1.00 18.60  ? 222 ILE B CG2 1 
ATOM   5010  C CD1 . ILE B 1 201 ? 192.677 172.950 196.430 1.00 18.60  ? 222 ILE B CD1 1 
ATOM   5011  N N   . GLN B 1 202 ? 187.977 174.090 194.099 1.00 19.46  ? 223 GLN B N   1 
ATOM   5012  C CA  . GLN B 1 202 ? 186.687 174.609 194.545 1.00 19.46  ? 223 GLN B CA  1 
ATOM   5013  C C   . GLN B 1 202 ? 185.812 173.494 195.107 1.00 19.46  ? 223 GLN B C   1 
ATOM   5014  O O   . GLN B 1 202 ? 185.199 173.648 196.173 1.00 19.46  ? 223 GLN B O   1 
ATOM   5015  C CB  . GLN B 1 202 ? 185.984 175.321 193.389 1.00 19.46  ? 223 GLN B CB  1 
ATOM   5016  C CG  . GLN B 1 202 ? 184.592 175.834 193.717 1.00 19.46  ? 223 GLN B CG  1 
ATOM   5017  C CD  . GLN B 1 202 ? 184.580 176.773 194.904 1.00 19.46  ? 223 GLN B CD  1 
ATOM   5018  O OE1 . GLN B 1 202 ? 184.096 176.425 195.981 1.00 19.46  ? 223 GLN B OE1 1 
ATOM   5019  N NE2 . GLN B 1 202 ? 185.113 177.973 194.714 1.00 19.46  ? 223 GLN B NE2 1 
ATOM   5020  N N   . ALA B 1 203 ? 185.764 172.354 194.412 1.00 18.04  ? 224 ALA B N   1 
ATOM   5021  C CA  . ALA B 1 203 ? 185.028 171.198 194.912 1.00 18.04  ? 224 ALA B CA  1 
ATOM   5022  C C   . ALA B 1 203 ? 185.667 170.628 196.170 1.00 18.04  ? 224 ALA B C   1 
ATOM   5023  O O   . ALA B 1 203 ? 184.958 170.140 197.055 1.00 18.04  ? 224 ALA B O   1 
ATOM   5024  C CB  . ALA B 1 203 ? 184.936 170.126 193.828 1.00 18.04  ? 224 ALA B CB  1 
ATOM   5025  N N   . LEU B 1 204 ? 186.996 170.693 196.271 1.00 15.99  ? 225 LEU B N   1 
ATOM   5026  C CA  . LEU B 1 204 ? 187.669 170.259 197.490 1.00 15.99  ? 225 LEU B CA  1 
ATOM   5027  C C   . LEU B 1 204 ? 187.401 171.224 198.641 1.00 15.99  ? 225 LEU B C   1 
ATOM   5028  O O   . LEU B 1 204 ? 187.263 170.801 199.795 1.00 15.99  ? 225 LEU B O   1 
ATOM   5029  C CB  . LEU B 1 204 ? 189.168 170.115 197.228 1.00 15.99  ? 225 LEU B CB  1 
ATOM   5030  C CG  . LEU B 1 204 ? 190.049 169.710 198.406 1.00 15.99  ? 225 LEU B CG  1 
ATOM   5031  C CD1 . LEU B 1 204 ? 189.591 168.367 198.929 1.00 15.99  ? 225 LEU B CD1 1 
ATOM   5032  C CD2 . LEU B 1 204 ? 191.508 169.659 197.994 1.00 15.99  ? 225 LEU B CD2 1 
ATOM   5033  N N   . SER B 1 205 ? 187.293 172.521 198.346 1.00 18.31  ? 226 SER B N   1 
ATOM   5034  C CA  . SER B 1 205 ? 186.950 173.507 199.362 1.00 18.31  ? 226 SER B CA  1 
ATOM   5035  C C   . SER B 1 205 ? 185.477 173.475 199.745 1.00 18.31  ? 226 SER B C   1 
ATOM   5036  O O   . SER B 1 205 ? 185.108 174.070 200.762 1.00 18.31  ? 226 SER B O   1 
ATOM   5037  C CB  . SER B 1 205 ? 187.319 174.910 198.881 1.00 18.31  ? 226 SER B CB  1 
ATOM   5038  O OG  . SER B 1 205 ? 186.459 175.327 197.837 1.00 18.31  ? 226 SER B OG  1 
ATOM   5039  N N   . GLN B 1 206 ? 184.633 172.811 198.949 1.00 15.97  ? 227 GLN B N   1 
ATOM   5040  C CA  . GLN B 1 206 ? 183.231 172.618 199.322 1.00 15.97  ? 227 GLN B CA  1 
ATOM   5041  C C   . GLN B 1 206 ? 183.049 171.746 200.563 1.00 15.97  ? 227 GLN B C   1 
ATOM   5042  O O   . GLN B 1 206 ? 181.973 171.780 201.169 1.00 15.97  ? 227 GLN B O   1 
ATOM   5043  C CB  . GLN B 1 206 ? 182.451 172.002 198.160 1.00 15.97  ? 227 GLN B CB  1 
ATOM   5044  C CG  . GLN B 1 206 ? 182.027 172.990 197.093 1.00 15.97  ? 227 GLN B CG  1 
ATOM   5045  C CD  . GLN B 1 206 ? 180.951 173.936 197.582 1.00 15.97  ? 227 GLN B CD  1 
ATOM   5046  O OE1 . GLN B 1 206 ? 180.063 173.544 198.338 1.00 15.97  ? 227 GLN B OE1 1 
ATOM   5047  N NE2 . GLN B 1 206 ? 181.022 175.189 197.149 1.00 15.97  ? 227 GLN B NE2 1 
ATOM   5048  N N   . LEU B 1 207 ? 184.058 170.959 200.951 1.00 13.41  ? 228 LEU B N   1 
ATOM   5049  C CA  . LEU B 1 207 ? 183.958 170.175 202.179 1.00 13.41  ? 228 LEU B CA  1 
ATOM   5050  C C   . LEU B 1 207 ? 184.043 171.050 203.424 1.00 13.41  ? 228 LEU B C   1 
ATOM   5051  O O   . LEU B 1 207 ? 183.535 170.665 204.483 1.00 13.41  ? 228 LEU B O   1 
ATOM   5052  C CB  . LEU B 1 207 ? 185.053 169.109 202.220 1.00 13.41  ? 228 LEU B CB  1 
ATOM   5053  C CG  . LEU B 1 207 ? 184.907 167.896 201.304 1.00 13.41  ? 228 LEU B CG  1 
ATOM   5054  C CD1 . LEU B 1 207 ? 185.978 166.869 201.623 1.00 13.41  ? 228 LEU B CD1 1 
ATOM   5055  C CD2 . LEU B 1 207 ? 183.525 167.288 201.451 1.00 13.41  ? 228 LEU B CD2 1 
ATOM   5056  N N   . PHE B 1 208 ? 184.674 172.218 203.322 1.00 21.33  ? 229 PHE B N   1 
ATOM   5057  C CA  . PHE B 1 208 ? 184.876 173.120 204.454 1.00 21.33  ? 229 PHE B CA  1 
ATOM   5058  C C   . PHE B 1 208 ? 183.915 174.300 204.418 1.00 21.33  ? 229 PHE B C   1 
ATOM   5059  O O   . PHE B 1 208 ? 184.296 175.424 204.763 1.00 21.33  ? 229 PHE B O   1 
ATOM   5060  C CB  . PHE B 1 208 ? 186.322 173.600 204.492 1.00 21.33  ? 229 PHE B CB  1 
ATOM   5061  C CG  . PHE B 1 208 ? 187.313 172.536 204.135 1.00 21.33  ? 229 PHE B CG  1 
ATOM   5062  C CD1 . PHE B 1 208 ? 187.476 171.428 204.950 1.00 21.33  ? 229 PHE B CD1 1 
ATOM   5063  C CD2 . PHE B 1 208 ? 188.062 172.628 202.975 1.00 21.33  ? 229 PHE B CD2 1 
ATOM   5064  C CE1 . PHE B 1 208 ? 188.381 170.438 204.624 1.00 21.33  ? 229 PHE B CE1 1 
ATOM   5065  C CE2 . PHE B 1 208 ? 188.968 171.639 202.642 1.00 21.33  ? 229 PHE B CE2 1 
ATOM   5066  C CZ  . PHE B 1 208 ? 189.124 170.543 203.466 1.00 21.33  ? 229 PHE B CZ  1 
ATOM   5067  N N   . GLU B 1 209 ? 182.665 174.032 204.015 1.00 28.17  ? 230 GLU B N   1 
ATOM   5068  C CA  . GLU B 1 209 ? 181.588 175.023 203.867 1.00 28.17  ? 230 GLU B CA  1 
ATOM   5069  C C   . GLU B 1 209 ? 181.982 176.173 202.941 1.00 28.17  ? 230 GLU B C   1 
ATOM   5070  O O   . GLU B 1 209 ? 181.682 177.338 203.208 1.00 28.17  ? 230 GLU B O   1 
ATOM   5071  C CB  . GLU B 1 209 ? 181.101 175.555 205.222 1.00 28.17  ? 230 GLU B CB  1 
ATOM   5072  C CG  . GLU B 1 209 ? 180.301 174.553 206.053 1.00 28.17  ? 230 GLU B CG  1 
ATOM   5073  C CD  . GLU B 1 209 ? 181.155 173.684 206.961 1.00 28.17  ? 230 GLU B CD  1 
ATOM   5074  O OE1 . GLU B 1 209 ? 182.373 173.929 207.063 1.00 28.17  ? 230 GLU B OE1 1 
ATOM   5075  O OE2 . GLU B 1 209 ? 180.602 172.747 207.574 1.00 28.17  ? 230 GLU B OE2 1 
ATOM   5076  N N   . GLY B 1 210 ? 182.646 175.838 201.836 1.00 21.18  ? 231 GLY B N   1 
ATOM   5077  C CA  . GLY B 1 210 ? 183.033 176.821 200.842 1.00 21.18  ? 231 GLY B CA  1 
ATOM   5078  C C   . GLY B 1 210 ? 184.088 177.805 201.302 1.00 21.18  ? 231 GLY B C   1 
ATOM   5079  O O   . GLY B 1 210 ? 183.923 179.017 201.139 1.00 21.18  ? 231 GLY B O   1 
ATOM   5080  N N   . ASN B 1 211 ? 185.177 177.302 201.877 1.00 19.11  ? 232 ASN B N   1 
ATOM   5081  C CA  . ASN B 1 211 ? 186.254 178.139 202.400 1.00 19.11  ? 232 ASN B CA  1 
ATOM   5082  C C   . ASN B 1 211 ? 187.503 177.871 201.565 1.00 19.11  ? 232 ASN B C   1 
ATOM   5083  O O   . ASN B 1 211 ? 188.334 177.032 201.918 1.00 19.11  ? 232 ASN B O   1 
ATOM   5084  C CB  . ASN B 1 211 ? 186.496 177.856 203.877 1.00 19.11  ? 232 ASN B CB  1 
ATOM   5085  C CG  . ASN B 1 211 ? 187.168 179.010 204.586 1.00 19.11  ? 232 ASN B CG  1 
ATOM   5086  O OD1 . ASN B 1 211 ? 187.627 179.959 203.952 1.00 19.11  ? 232 ASN B OD1 1 
ATOM   5087  N ND2 . ASN B 1 211 ? 187.228 178.937 205.910 1.00 19.11  ? 232 ASN B ND2 1 
ATOM   5088  N N   . LEU B 1 212 ? 187.631 178.598 200.454 1.00 16.04  ? 233 LEU B N   1 
ATOM   5089  C CA  . LEU B 1 212 ? 188.782 178.442 199.574 1.00 16.04  ? 233 LEU B CA  1 
ATOM   5090  C C   . LEU B 1 212 ? 190.025 179.110 200.149 1.00 16.04  ? 233 LEU B C   1 
ATOM   5091  O O   . LEU B 1 212 ? 191.143 178.624 199.931 1.00 16.04  ? 233 LEU B O   1 
ATOM   5092  C CB  . LEU B 1 212 ? 188.444 179.008 198.189 1.00 16.04  ? 233 LEU B CB  1 
ATOM   5093  C CG  . LEU B 1 212 ? 189.179 178.616 196.900 1.00 16.04  ? 233 LEU B CG  1 
ATOM   5094  C CD1 . LEU B 1 212 ? 188.292 178.959 195.720 1.00 16.04  ? 233 LEU B CD1 1 
ATOM   5095  C CD2 . LEU B 1 212 ? 190.525 179.303 196.720 1.00 16.04  ? 233 LEU B CD2 1 
ATOM   5096  N N   . GLU B 1 213 ? 189.847 180.216 200.879 1.00 22.12  ? 234 GLU B N   1 
ATOM   5097  C CA  . GLU B 1 213 ? 190.990 180.969 201.384 1.00 22.12  ? 234 GLU B CA  1 
ATOM   5098  C C   . GLU B 1 213 ? 191.715 180.225 202.496 1.00 22.12  ? 234 GLU B C   1 
ATOM   5099  O O   . GLU B 1 213 ? 192.926 180.404 202.659 1.00 22.12  ? 234 GLU B O   1 
ATOM   5100  C CB  . GLU B 1 213 ? 190.545 182.348 201.868 1.00 22.12  ? 234 GLU B CB  1 
ATOM   5101  C CG  . GLU B 1 213 ? 191.641 183.405 201.823 1.00 22.12  ? 234 GLU B CG  1 
ATOM   5102  C CD  . GLU B 1 213 ? 192.129 183.708 200.418 1.00 22.12  ? 234 GLU B CD  1 
ATOM   5103  O OE1 . GLU B 1 213 ? 191.315 183.660 199.471 1.00 22.12  ? 234 GLU B OE1 1 
ATOM   5104  O OE2 . GLU B 1 213 ? 193.333 183.999 200.262 1.00 22.12  ? 234 GLU B OE2 1 
ATOM   5105  N N   . LEU B 1 214 ? 191.003 179.380 203.251 1.00 15.89  ? 235 LEU B N   1 
ATOM   5106  C CA  . LEU B 1 214 ? 191.657 178.534 204.246 1.00 15.89  ? 235 LEU B CA  1 
ATOM   5107  C C   . LEU B 1 214 ? 192.596 177.530 203.591 1.00 15.89  ? 235 LEU B C   1 
ATOM   5108  O O   . LEU B 1 214 ? 193.738 177.365 204.036 1.00 15.89  ? 235 LEU B O   1 
ATOM   5109  C CB  . LEU B 1 214 ? 190.613 177.808 205.093 1.00 15.89  ? 235 LEU B CB  1 
ATOM   5110  C CG  . LEU B 1 214 ? 191.158 176.946 206.234 1.00 15.89  ? 235 LEU B CG  1 
ATOM   5111  C CD1 . LEU B 1 214 ? 192.041 177.767 207.159 1.00 15.89  ? 235 LEU B CD1 1 
ATOM   5112  C CD2 . LEU B 1 214 ? 190.024 176.297 207.009 1.00 15.89  ? 235 LEU B CD2 1 
ATOM   5113  N N   . LEU B 1 215 ? 192.142 176.880 202.513 1.00 11.20  ? 236 LEU B N   1 
ATOM   5114  C CA  . LEU B 1 215 ? 192.991 175.954 201.769 1.00 11.20  ? 236 LEU B CA  1 
ATOM   5115  C C   . LEU B 1 215 ? 194.159 176.664 201.099 1.00 11.20  ? 236 LEU B C   1 
ATOM   5116  O O   . LEU B 1 215 ? 195.275 176.132 201.084 1.00 11.20  ? 236 LEU B O   1 
ATOM   5117  C CB  . LEU B 1 215 ? 192.168 175.214 200.717 1.00 11.20  ? 236 LEU B CB  1 
ATOM   5118  C CG  . LEU B 1 215 ? 191.455 173.931 201.134 1.00 11.20  ? 236 LEU B CG  1 
ATOM   5119  C CD1 . LEU B 1 215 ? 190.698 173.364 199.949 1.00 11.20  ? 236 LEU B CD1 1 
ATOM   5120  C CD2 . LEU B 1 215 ? 192.449 172.921 201.673 1.00 11.20  ? 236 LEU B CD2 1 
ATOM   5121  N N   . THR B 1 216 ? 193.921 177.859 200.550 1.00 17.61  ? 237 THR B N   1 
ATOM   5122  C CA  . THR B 1 216 ? 194.983 178.599 199.871 1.00 17.61  ? 237 THR B CA  1 
ATOM   5123  C C   . THR B 1 216 ? 196.043 179.082 200.861 1.00 17.61  ? 237 THR B C   1 
ATOM   5124  O O   . THR B 1 216 ? 197.247 178.950 200.609 1.00 17.61  ? 237 THR B O   1 
ATOM   5125  C CB  . THR B 1 216 ? 194.368 179.764 199.087 1.00 17.61  ? 237 THR B CB  1 
ATOM   5126  O OG1 . THR B 1 216 ? 193.671 179.249 197.947 1.00 17.61  ? 237 THR B OG1 1 
ATOM   5127  C CG2 . THR B 1 216 ? 195.429 180.743 198.600 1.00 17.61  ? 237 THR B CG2 1 
ATOM   5128  N N   . SER B 1 217 ? 195.615 179.594 202.021 1.00 19.76  ? 238 SER B N   1 
ATOM   5129  C CA  . SER B 1 217 ? 196.564 180.073 203.021 1.00 19.76  ? 238 SER B CA  1 
ATOM   5130  C C   . SER B 1 217 ? 197.287 178.927 203.718 1.00 19.76  ? 238 SER B C   1 
ATOM   5131  O O   . SER B 1 217 ? 198.467 179.065 204.060 1.00 19.76  ? 238 SER B O   1 
ATOM   5132  C CB  . SER B 1 217 ? 195.846 180.948 204.047 1.00 19.76  ? 238 SER B CB  1 
ATOM   5133  O OG  . SER B 1 217 ? 196.747 181.409 205.039 1.00 19.76  ? 238 SER B OG  1 
ATOM   5134  N N   . SER B 1 218 ? 196.610 177.797 203.944 1.00 19.79  ? 239 SER B N   1 
ATOM   5135  C CA  . SER B 1 218 ? 197.280 176.642 204.524 1.00 19.79  ? 239 SER B CA  1 
ATOM   5136  C C   . SER B 1 218 ? 198.195 175.945 203.531 1.00 19.79  ? 239 SER B C   1 
ATOM   5137  O O   . SER B 1 218 ? 199.120 175.242 203.950 1.00 19.79  ? 239 SER B O   1 
ATOM   5138  C CB  . SER B 1 218 ? 196.252 175.647 205.056 1.00 19.79  ? 239 SER B CB  1 
ATOM   5139  O OG  . SER B 1 218 ? 196.891 174.486 205.555 1.00 19.79  ? 239 SER B OG  1 
ATOM   5140  N N   . LEU B 1 219 ? 197.950 176.111 202.231 1.00 22.61  ? 240 LEU B N   1 
ATOM   5141  C CA  . LEU B 1 219 ? 198.797 175.473 201.233 1.00 22.61  ? 240 LEU B CA  1 
ATOM   5142  C C   . LEU B 1 219 ? 200.163 176.142 201.144 1.00 22.61  ? 240 LEU B C   1 
ATOM   5143  O O   . LEU B 1 219 ? 201.189 175.458 201.096 1.00 22.61  ? 240 LEU B O   1 
ATOM   5144  C CB  . LEU B 1 219 ? 198.103 175.486 199.872 1.00 22.61  ? 240 LEU B CB  1 
ATOM   5145  C CG  . LEU B 1 219 ? 198.820 174.700 198.780 1.00 22.61  ? 240 LEU B CG  1 
ATOM   5146  C CD1 . LEU B 1 219 ? 199.033 173.274 199.247 1.00 22.61  ? 240 LEU B CD1 1 
ATOM   5147  C CD2 . LEU B 1 219 ? 198.026 174.732 197.487 1.00 22.61  ? 240 LEU B CD2 1 
ATOM   5148  N N   . GLY B 1 220 ? 200.202 177.470 201.142 1.00 30.51  ? 241 GLY B N   1 
ATOM   5149  C CA  . GLY B 1 220 ? 201.438 178.222 201.041 1.00 30.51  ? 241 GLY B CA  1 
ATOM   5150  C C   . GLY B 1 220 ? 201.449 179.258 199.939 1.00 30.51  ? 241 GLY B C   1 
ATOM   5151  O O   . GLY B 1 220 ? 202.281 180.175 199.975 1.00 30.51  ? 241 GLY B O   1 
ATOM   5152  N N   . ILE B 1 221 ? 200.559 179.141 198.955 1.00 36.54  ? 242 ILE B N   1 
ATOM   5153  C CA  . ILE B 1 221 ? 200.440 180.169 197.930 1.00 36.54  ? 242 ILE B CA  1 
ATOM   5154  C C   . ILE B 1 221 ? 199.757 181.395 198.527 1.00 36.54  ? 242 ILE B C   1 
ATOM   5155  O O   . ILE B 1 221 ? 198.725 181.292 199.202 1.00 36.54  ? 242 ILE B O   1 
ATOM   5156  C CB  . ILE B 1 221 ? 199.700 179.616 196.697 1.00 36.54  ? 242 ILE B CB  1 
ATOM   5157  C CG1 . ILE B 1 221 ? 199.450 180.714 195.658 1.00 36.54  ? 242 ILE B CG1 1 
ATOM   5158  C CG2 . ILE B 1 221 ? 198.426 178.856 197.080 1.00 36.54  ? 242 ILE B CG2 1 
ATOM   5159  C CD1 . ILE B 1 221 ? 198.953 180.191 194.329 1.00 36.54  ? 242 ILE B CD1 1 
ATOM   5160  N N   . SER B 1 222 ? 200.363 182.563 198.321 1.00 63.33  ? 243 SER B N   1 
ATOM   5161  C CA  . SER B 1 222 ? 199.859 183.815 198.888 1.00 63.33  ? 243 SER B CA  1 
ATOM   5162  C C   . SER B 1 222 ? 199.872 184.863 197.781 1.00 63.33  ? 243 SER B C   1 
ATOM   5163  O O   . SER B 1 222 ? 200.934 185.379 197.420 1.00 63.33  ? 243 SER B O   1 
ATOM   5164  C CB  . SER B 1 222 ? 200.695 184.257 200.083 1.00 63.33  ? 243 SER B CB  1 
ATOM   5165  O OG  . SER B 1 222 ? 200.018 185.245 200.839 1.00 63.33  ? 243 SER B OG  1 
ATOM   5166  N N   . SER B 1 223 ? 198.694 185.165 197.244 1.00 87.74  ? 244 SER B N   1 
ATOM   5167  C CA  . SER B 1 223 ? 198.584 186.160 196.187 1.00 87.74  ? 244 SER B CA  1 
ATOM   5168  C C   . SER B 1 223 ? 198.781 187.561 196.749 1.00 87.74  ? 244 SER B C   1 
ATOM   5169  O O   . SER B 1 223 ? 198.295 187.888 197.836 1.00 87.74  ? 244 SER B O   1 
ATOM   5170  C CB  . SER B 1 223 ? 197.224 186.055 195.500 1.00 87.74  ? 244 SER B CB  1 
ATOM   5171  O OG  . SER B 1 223 ? 197.057 184.785 194.894 1.00 87.74  ? 244 SER B OG  1 
ATOM   5172  N N   . THR B 1 224 ? 199.501 188.394 195.998 1.00 105.12 ? 245 THR B N   1 
ATOM   5173  C CA  . THR B 1 224 ? 199.777 189.760 196.415 1.00 105.12 ? 245 THR B CA  1 
ATOM   5174  C C   . THR B 1 224 ? 199.431 190.807 195.368 1.00 105.12 ? 245 THR B C   1 
ATOM   5175  O O   . THR B 1 224 ? 199.417 191.997 195.701 1.00 105.12 ? 245 THR B O   1 
ATOM   5176  C CB  . THR B 1 224 ? 201.256 189.917 196.805 1.00 105.12 ? 245 THR B CB  1 
ATOM   5177  O OG1 . THR B 1 224 ? 201.474 191.223 197.353 1.00 105.12 ? 245 THR B OG1 1 
ATOM   5178  C CG2 . THR B 1 224 ? 202.159 189.718 195.596 1.00 105.12 ? 245 THR B CG2 1 
ATOM   5179  N N   . ASP B 1 225 ? 199.151 190.416 194.130 1.00 90.69  ? 246 ASP B N   1 
ATOM   5180  C CA  . ASP B 1 225 ? 198.796 191.343 193.068 1.00 90.69  ? 246 ASP B CA  1 
ATOM   5181  C C   . ASP B 1 225 ? 197.351 191.110 192.634 1.00 90.69  ? 246 ASP B C   1 
ATOM   5182  O O   . ASP B 1 225 ? 196.680 190.178 193.086 1.00 90.69  ? 246 ASP B O   1 
ATOM   5183  C CB  . ASP B 1 225 ? 199.768 191.214 191.892 1.00 90.69  ? 246 ASP B CB  1 
ATOM   5184  C CG  . ASP B 1 225 ? 199.956 189.778 191.441 1.00 90.69  ? 246 ASP B CG  1 
ATOM   5185  O OD1 . ASP B 1 225 ? 199.465 188.863 192.132 1.00 90.69  ? 246 ASP B OD1 1 
ATOM   5186  O OD2 . ASP B 1 225 ? 200.601 189.565 190.392 1.00 90.69  ? 246 ASP B OD2 1 
ATOM   5187  N N   . PHE B 1 226 ? 196.878 191.981 191.742 1.00 67.61  ? 247 PHE B N   1 
ATOM   5188  C CA  . PHE B 1 226 ? 195.474 191.961 191.346 1.00 67.61  ? 247 PHE B CA  1 
ATOM   5189  C C   . PHE B 1 226 ? 195.160 190.803 190.405 1.00 67.61  ? 247 PHE B C   1 
ATOM   5190  O O   . PHE B 1 226 ? 194.024 190.315 190.385 1.00 67.61  ? 247 PHE B O   1 
ATOM   5191  C CB  . PHE B 1 226 ? 195.107 193.299 190.701 1.00 67.61  ? 247 PHE B CB  1 
ATOM   5192  C CG  . PHE B 1 226 ? 193.670 193.404 190.290 1.00 67.61  ? 247 PHE B CG  1 
ATOM   5193  C CD1 . PHE B 1 226 ? 192.678 193.605 191.237 1.00 67.61  ? 247 PHE B CD1 1 
ATOM   5194  C CD2 . PHE B 1 226 ? 193.311 193.312 188.952 1.00 67.61  ? 247 PHE B CD2 1 
ATOM   5195  C CE1 . PHE B 1 226 ? 191.352 193.703 190.860 1.00 67.61  ? 247 PHE B CE1 1 
ATOM   5196  C CE2 . PHE B 1 226 ? 191.988 193.409 188.567 1.00 67.61  ? 247 PHE B CE2 1 
ATOM   5197  C CZ  . PHE B 1 226 ? 191.009 193.606 189.522 1.00 67.61  ? 247 PHE B CZ  1 
ATOM   5198  N N   . ASN B 1 227 ? 196.145 190.347 189.629 1.00 71.04  ? 248 ASN B N   1 
ATOM   5199  C CA  . ASN B 1 227 ? 195.890 189.299 188.646 1.00 71.04  ? 248 ASN B CA  1 
ATOM   5200  C C   . ASN B 1 227 ? 195.727 187.932 189.298 1.00 71.04  ? 248 ASN B C   1 
ATOM   5201  O O   . ASN B 1 227 ? 195.039 187.064 188.749 1.00 71.04  ? 248 ASN B O   1 
ATOM   5202  C CB  . ASN B 1 227 ? 197.017 189.272 187.613 1.00 71.04  ? 248 ASN B CB  1 
ATOM   5203  C CG  . ASN B 1 227 ? 196.666 188.457 186.385 1.00 71.04  ? 248 ASN B CG  1 
ATOM   5204  O OD1 . ASN B 1 227 ? 196.748 187.230 186.395 1.00 71.04  ? 248 ASN B OD1 1 
ATOM   5205  N ND2 . ASN B 1 227 ? 196.267 189.140 185.319 1.00 71.04  ? 248 ASN B ND2 1 
ATOM   5206  N N   . ASP B 1 228 ? 196.332 187.723 190.465 1.00 67.52  ? 249 ASP B N   1 
ATOM   5207  C CA  . ASP B 1 228 ? 196.282 186.440 191.152 1.00 67.52  ? 249 ASP B CA  1 
ATOM   5208  C C   . ASP B 1 228 ? 195.182 186.382 192.207 1.00 67.52  ? 249 ASP B C   1 
ATOM   5209  O O   . ASP B 1 228 ? 195.110 185.405 192.959 1.00 67.52  ? 249 ASP B O   1 
ATOM   5210  C CB  . ASP B 1 228 ? 197.641 186.132 191.785 1.00 67.52  ? 249 ASP B CB  1 
ATOM   5211  C CG  . ASP B 1 228 ? 197.934 184.645 191.850 1.00 67.52  ? 249 ASP B CG  1 
ATOM   5212  O OD1 . ASP B 1 228 ? 197.117 183.853 191.336 1.00 67.52  ? 249 ASP B OD1 1 
ATOM   5213  O OD2 . ASP B 1 228 ? 198.982 184.271 192.415 1.00 67.52  ? 249 ASP B OD2 1 
ATOM   5214  N N   . LEU B 1 229 ? 194.333 187.407 192.292 1.00 54.13  ? 250 LEU B N   1 
ATOM   5215  C CA  . LEU B 1 229 ? 193.212 187.360 193.225 1.00 54.13  ? 250 LEU B CA  1 
ATOM   5216  C C   . LEU B 1 229 ? 192.050 186.559 192.651 1.00 54.13  ? 250 LEU B C   1 
ATOM   5217  O O   . LEU B 1 229 ? 191.499 185.683 193.326 1.00 54.13  ? 250 LEU B O   1 
ATOM   5218  C CB  . LEU B 1 229 ? 192.764 188.776 193.587 1.00 54.13  ? 250 LEU B CB  1 
ATOM   5219  C CG  . LEU B 1 229 ? 193.671 189.538 194.553 1.00 54.13  ? 250 LEU B CG  1 
ATOM   5220  C CD1 . LEU B 1 229 ? 193.188 190.968 194.731 1.00 54.13  ? 250 LEU B CD1 1 
ATOM   5221  C CD2 . LEU B 1 229 ? 193.742 188.823 195.893 1.00 54.13  ? 250 LEU B CD2 1 
ATOM   5222  N N   . LEU B 1 230 ? 191.658 186.855 191.409 1.00 45.37  ? 251 LEU B N   1 
ATOM   5223  C CA  . LEU B 1 230 ? 190.626 186.061 190.750 1.00 45.37  ? 251 LEU B CA  1 
ATOM   5224  C C   . LEU B 1 230 ? 191.132 184.670 190.396 1.00 45.37  ? 251 LEU B C   1 
ATOM   5225  O O   . LEU B 1 230 ? 190.351 183.711 190.389 1.00 45.37  ? 251 LEU B O   1 
ATOM   5226  C CB  . LEU B 1 230 ? 190.124 186.779 189.499 1.00 45.37  ? 251 LEU B CB  1 
ATOM   5227  C CG  . LEU B 1 230 ? 189.344 188.069 189.748 1.00 45.37  ? 251 LEU B CG  1 
ATOM   5228  C CD1 . LEU B 1 230 ? 188.999 188.754 188.435 1.00 45.37  ? 251 LEU B CD1 1 
ATOM   5229  C CD2 . LEU B 1 230 ? 188.090 187.774 190.552 1.00 45.37  ? 251 LEU B CD2 1 
ATOM   5230  N N   . THR B 1 231 ? 192.420 184.546 190.084 1.00 52.02  ? 252 THR B N   1 
ATOM   5231  C CA  . THR B 1 231 ? 193.038 183.240 189.908 1.00 52.02  ? 252 THR B CA  1 
ATOM   5232  C C   . THR B 1 231 ? 193.095 182.530 191.258 1.00 52.02  ? 252 THR B C   1 
ATOM   5233  O O   . THR B 1 231 ? 193.446 183.136 192.274 1.00 52.02  ? 252 THR B O   1 
ATOM   5234  C CB  . THR B 1 231 ? 194.439 183.404 189.312 1.00 52.02  ? 252 THR B CB  1 
ATOM   5235  O OG1 . THR B 1 231 ? 194.344 184.102 188.064 1.00 52.02  ? 252 THR B OG1 1 
ATOM   5236  C CG2 . THR B 1 231 ? 195.107 182.056 189.063 1.00 52.02  ? 252 THR B CG2 1 
ATOM   5237  N N   . GLY B 1 232 ? 192.744 181.248 191.273 1.00 30.70  ? 253 GLY B N   1 
ATOM   5238  C CA  . GLY B 1 232 ? 192.614 180.532 192.524 1.00 30.70  ? 253 GLY B CA  1 
ATOM   5239  C C   . GLY B 1 232 ? 191.519 179.493 192.466 1.00 30.70  ? 253 GLY B C   1 
ATOM   5240  O O   . GLY B 1 232 ? 191.346 178.703 193.397 1.00 30.70  ? 253 GLY B O   1 
ATOM   5241  N N   . LYS B 1 233 ? 190.765 179.494 191.369 1.00 28.88  ? 254 LYS B N   1 
ATOM   5242  C CA  . LYS B 1 233 ? 189.789 178.455 191.082 1.00 28.88  ? 254 LYS B CA  1 
ATOM   5243  C C   . LYS B 1 233 ? 190.323 177.432 190.087 1.00 28.88  ? 254 LYS B C   1 
ATOM   5244  O O   . LYS B 1 233 ? 189.536 176.756 189.416 1.00 28.88  ? 254 LYS B O   1 
ATOM   5245  C CB  . LYS B 1 233 ? 188.494 179.081 190.562 1.00 28.88  ? 254 LYS B CB  1 
ATOM   5246  C CG  . LYS B 1 233 ? 188.101 180.364 191.280 1.00 28.88  ? 254 LYS B CG  1 
ATOM   5247  C CD  . LYS B 1 233 ? 187.005 181.108 190.533 1.00 28.88  ? 254 LYS B CD  1 
ATOM   5248  C CE  . LYS B 1 233 ? 186.776 182.489 191.128 1.00 28.88  ? 254 LYS B CE  1 
ATOM   5249  N NZ  . LYS B 1 233 ? 185.833 183.303 190.310 1.00 28.88  ? 254 LYS B NZ  1 
ATOM   5250  N N   . LEU B 1 234 ? 191.647 177.309 189.977 1.00 31.82  ? 255 LEU B N   1 
ATOM   5251  C CA  . LEU B 1 234 ? 192.252 176.424 188.993 1.00 31.82  ? 255 LEU B CA  1 
ATOM   5252  C C   . LEU B 1 234 ? 193.441 175.626 189.517 1.00 31.82  ? 255 LEU B C   1 
ATOM   5253  O O   . LEU B 1 234 ? 194.148 175.016 188.709 1.00 31.82  ? 255 LEU B O   1 
ATOM   5254  C CB  . LEU B 1 234 ? 192.648 177.238 187.738 1.00 31.82  ? 255 LEU B CB  1 
ATOM   5255  C CG  . LEU B 1 234 ? 193.641 178.415 187.749 1.00 31.82  ? 255 LEU B CG  1 
ATOM   5256  C CD1 . LEU B 1 234 ? 195.118 178.028 187.636 1.00 31.82  ? 255 LEU B CD1 1 
ATOM   5257  C CD2 . LEU B 1 234 ? 193.268 179.428 186.672 1.00 31.82  ? 255 LEU B CD2 1 
ATOM   5258  N N   . ILE B 1 235 ? 193.686 175.608 190.828 1.00 27.37  ? 256 ILE B N   1 
ATOM   5259  C CA  . ILE B 1 235 ? 194.693 174.714 191.388 1.00 27.37  ? 256 ILE B CA  1 
ATOM   5260  C C   . ILE B 1 235 ? 194.163 173.287 191.343 1.00 27.37  ? 256 ILE B C   1 
ATOM   5261  O O   . ILE B 1 235 ? 193.055 173.003 191.816 1.00 27.37  ? 256 ILE B O   1 
ATOM   5262  C CB  . ILE B 1 235 ? 195.080 175.135 192.818 1.00 27.37  ? 256 ILE B CB  1 
ATOM   5263  C CG1 . ILE B 1 235 ? 195.814 176.484 192.847 1.00 27.37  ? 256 ILE B CG1 1 
ATOM   5264  C CG2 . ILE B 1 235 ? 195.944 174.080 193.491 1.00 27.37  ? 256 ILE B CG2 1 
ATOM   5265  C CD1 . ILE B 1 235 ? 194.953 177.708 193.058 1.00 27.37  ? 256 ILE B CD1 1 
ATOM   5266  N N   . THR B 1 236 ? 194.952 172.383 190.768 1.00 28.54  ? 257 THR B N   1 
ATOM   5267  C CA  . THR B 1 236 ? 194.513 171.033 190.443 1.00 28.54  ? 257 THR B CA  1 
ATOM   5268  C C   . THR B 1 236 ? 195.326 170.024 191.244 1.00 28.54  ? 257 THR B C   1 
ATOM   5269  O O   . THR B 1 236 ? 196.557 170.107 191.283 1.00 28.54  ? 257 THR B O   1 
ATOM   5270  C CB  . THR B 1 236 ? 194.664 170.787 188.938 1.00 28.54  ? 257 THR B CB  1 
ATOM   5271  O OG1 . THR B 1 236 ? 193.875 171.743 188.219 1.00 28.54  ? 257 THR B OG1 1 
ATOM   5272  C CG2 . THR B 1 236 ? 194.206 169.402 188.560 1.00 28.54  ? 257 THR B CG2 1 
ATOM   5273  N N   . GLY B 1 237 ? 194.637 169.075 191.882 1.00 25.88  ? 258 GLY B N   1 
ATOM   5274  C CA  . GLY B 1 237 ? 195.304 168.064 192.677 1.00 25.88  ? 258 GLY B CA  1 
ATOM   5275  C C   . GLY B 1 237 ? 194.764 166.680 192.377 1.00 25.88  ? 258 GLY B C   1 
ATOM   5276  O O   . GLY B 1 237 ? 193.658 166.517 191.857 1.00 25.88  ? 258 GLY B O   1 
ATOM   5277  N N   . SER B 1 238 ? 195.571 165.676 192.720 1.00 29.11  ? 259 SER B N   1 
ATOM   5278  C CA  . SER B 1 238 ? 195.245 164.281 192.458 1.00 29.11  ? 259 SER B CA  1 
ATOM   5279  C C   . SER B 1 238 ? 195.608 163.418 193.660 1.00 29.11  ? 259 SER B C   1 
ATOM   5280  O O   . SER B 1 238 ? 196.445 163.785 194.488 1.00 29.11  ? 259 SER B O   1 
ATOM   5281  C CB  . SER B 1 238 ? 195.965 163.765 191.205 1.00 29.11  ? 259 SER B CB  1 
ATOM   5282  O OG  . SER B 1 238 ? 197.319 164.179 191.191 1.00 29.11  ? 259 SER B OG  1 
ATOM   5283  N N   . ILE B 1 239 ? 194.964 162.254 193.740 1.00 49.69  ? 260 ILE B N   1 
ATOM   5284  C CA  . ILE B 1 239 ? 195.116 161.332 194.862 1.00 49.69  ? 260 ILE B CA  1 
ATOM   5285  C C   . ILE B 1 239 ? 196.366 160.489 194.642 1.00 49.69  ? 260 ILE B C   1 
ATOM   5286  O O   . ILE B 1 239 ? 196.560 159.930 193.556 1.00 49.69  ? 260 ILE B O   1 
ATOM   5287  C CB  . ILE B 1 239 ? 193.871 160.435 195.009 1.00 49.69  ? 260 ILE B CB  1 
ATOM   5288  C CG1 . ILE B 1 239 ? 192.621 161.258 195.330 1.00 49.69  ? 260 ILE B CG1 1 
ATOM   5289  C CG2 . ILE B 1 239 ? 194.069 159.374 196.081 1.00 49.69  ? 260 ILE B CG2 1 
ATOM   5290  C CD1 . ILE B 1 239 ? 191.704 161.480 194.146 1.00 49.69  ? 260 ILE B CD1 1 
ATOM   5291  N N   . ILE B 1 240 ? 197.221 160.397 195.661 1.00 22.99  ? 261 ILE B N   1 
ATOM   5292  C CA  . ILE B 1 240 ? 198.350 159.479 195.613 1.00 22.99  ? 261 ILE B CA  1 
ATOM   5293  C C   . ILE B 1 240 ? 198.265 158.367 196.655 1.00 22.99  ? 261 ILE B C   1 
ATOM   5294  O O   . ILE B 1 240 ? 198.935 157.337 196.481 1.00 22.99  ? 261 ILE B O   1 
ATOM   5295  C CB  . ILE B 1 240 ? 199.702 160.215 195.735 1.00 22.99  ? 261 ILE B CB  1 
ATOM   5296  C CG1 . ILE B 1 240 ? 199.851 160.880 197.101 1.00 22.99  ? 261 ILE B CG1 1 
ATOM   5297  C CG2 . ILE B 1 240 ? 199.858 161.238 194.623 1.00 22.99  ? 261 ILE B CG2 1 
ATOM   5298  C CD1 . ILE B 1 240 ? 201.239 161.399 197.376 1.00 22.99  ? 261 ILE B CD1 1 
ATOM   5299  N N   . TRP B 1 241 ? 197.470 158.519 197.718 1.00 29.36  ? 262 TRP B N   1 
ATOM   5300  C CA  . TRP B 1 241 ? 197.331 157.418 198.667 1.00 29.36  ? 262 TRP B CA  1 
ATOM   5301  C C   . TRP B 1 241 ? 195.969 157.466 199.345 1.00 29.36  ? 262 TRP B C   1 
ATOM   5302  O O   . TRP B 1 241 ? 195.402 158.539 199.556 1.00 29.36  ? 262 TRP B O   1 
ATOM   5303  C CB  . TRP B 1 241 ? 198.437 157.431 199.726 1.00 29.36  ? 262 TRP B CB  1 
ATOM   5304  C CG  . TRP B 1 241 ? 198.611 156.125 200.425 1.00 29.36  ? 262 TRP B CG  1 
ATOM   5305  C CD1 . TRP B 1 241 ? 198.288 155.844 201.715 1.00 29.36  ? 262 TRP B CD1 1 
ATOM   5306  C CD2 . TRP B 1 241 ? 199.156 154.921 199.875 1.00 29.36  ? 262 TRP B CD2 1 
ATOM   5307  N NE1 . TRP B 1 241 ? 198.594 154.538 202.008 1.00 29.36  ? 262 TRP B NE1 1 
ATOM   5308  C CE2 . TRP B 1 241 ? 199.129 153.949 200.893 1.00 29.36  ? 262 TRP B CE2 1 
ATOM   5309  C CE3 . TRP B 1 241 ? 199.664 154.570 198.620 1.00 29.36  ? 262 TRP B CE3 1 
ATOM   5310  C CZ2 . TRP B 1 241 ? 199.589 152.649 200.697 1.00 29.36  ? 262 TRP B CZ2 1 
ATOM   5311  C CZ3 . TRP B 1 241 ? 200.120 153.279 198.426 1.00 29.36  ? 262 TRP B CZ3 1 
ATOM   5312  C CH2 . TRP B 1 241 ? 200.080 152.334 199.459 1.00 29.36  ? 262 TRP B CH2 1 
ATOM   5313  N N   . ALA B 1 242 ? 195.477 156.288 199.721 1.00 18.07  ? 263 ALA B N   1 
ATOM   5314  C CA  . ALA B 1 242 ? 194.114 156.091 200.211 1.00 18.07  ? 263 ALA B CA  1 
ATOM   5315  C C   . ALA B 1 242 ? 194.103 155.190 201.445 1.00 18.07  ? 263 ALA B C   1 
ATOM   5316  O O   . ALA B 1 242 ? 193.442 154.151 201.464 1.00 18.07  ? 263 ALA B O   1 
ATOM   5317  C CB  . ALA B 1 242 ? 193.226 155.512 199.116 1.00 18.07  ? 263 ALA B CB  1 
ATOM   5318  N N   . ASP B 1 243 ? 194.879 155.560 202.469 1.00 29.89  ? 264 ASP B N   1 
ATOM   5319  C CA  . ASP B 1 243 ? 195.142 154.667 203.598 1.00 29.89  ? 264 ASP B CA  1 
ATOM   5320  C C   . ASP B 1 243 ? 193.888 154.409 204.430 1.00 29.89  ? 264 ASP B C   1 
ATOM   5321  O O   . ASP B 1 243 ? 193.162 155.341 204.796 1.00 29.89  ? 264 ASP B O   1 
ATOM   5322  C CB  . ASP B 1 243 ? 196.238 155.250 204.488 1.00 29.89  ? 264 ASP B CB  1 
ATOM   5323  C CG  . ASP B 1 243 ? 196.926 154.195 205.331 1.00 29.89  ? 264 ASP B CG  1 
ATOM   5324  O OD1 . ASP B 1 243 ? 196.629 152.996 205.149 1.00 29.89  ? 264 ASP B OD1 1 
ATOM   5325  O OD2 . ASP B 1 243 ? 197.769 154.563 206.175 1.00 29.89  ? 264 ASP B OD2 1 
ATOM   5326  N N   . THR B 1 244 ? 193.659 153.131 204.742 1.00 28.56  ? 265 THR B N   1 
ATOM   5327  C CA  . THR B 1 244 ? 192.418 152.655 205.337 1.00 28.56  ? 265 THR B CA  1 
ATOM   5328  C C   . THR B 1 244 ? 192.482 152.502 206.850 1.00 28.56  ? 265 THR B C   1 
ATOM   5329  O O   . THR B 1 244 ? 191.429 152.359 207.481 1.00 28.56  ? 265 THR B O   1 
ATOM   5330  C CB  . THR B 1 244 ? 192.028 151.301 204.730 1.00 28.56  ? 265 THR B CB  1 
ATOM   5331  O OG1 . THR B 1 244 ? 192.930 150.293 205.201 1.00 28.56  ? 265 THR B OG1 1 
ATOM   5332  C CG2 . THR B 1 244 ? 192.110 151.352 203.218 1.00 28.56  ? 265 THR B CG2 1 
ATOM   5333  N N   . GLN B 1 245 ? 193.675 152.512 207.445 1.00 32.40  ? 266 GLN B N   1 
ATOM   5334  C CA  . GLN B 1 245 ? 193.783 152.310 208.887 1.00 32.40  ? 266 GLN B CA  1 
ATOM   5335  C C   . GLN B 1 245 ? 193.344 153.554 209.649 1.00 32.40  ? 266 GLN B C   1 
ATOM   5336  O O   . GLN B 1 245 ? 192.470 153.488 210.519 1.00 32.40  ? 266 GLN B O   1 
ATOM   5337  C CB  . GLN B 1 245 ? 195.216 151.924 209.259 1.00 32.40  ? 266 GLN B CB  1 
ATOM   5338  C CG  . GLN B 1 245 ? 195.513 150.444 209.104 1.00 32.40  ? 266 GLN B CG  1 
ATOM   5339  C CD  . GLN B 1 245 ? 196.998 150.147 209.104 1.00 32.40  ? 266 GLN B CD  1 
ATOM   5340  O OE1 . GLN B 1 245 ? 197.731 150.593 209.986 1.00 32.40  ? 266 GLN B OE1 1 
ATOM   5341  N NE2 . GLN B 1 245 ? 197.451 149.391 208.111 1.00 32.40  ? 266 GLN B NE2 1 
ATOM   5342  N N   . GLY B 1 246 ? 193.941 154.697 209.333 1.00 32.93  ? 267 GLY B N   1 
ATOM   5343  C CA  . GLY B 1 246 ? 193.481 155.956 209.872 1.00 32.93  ? 267 GLY B CA  1 
ATOM   5344  C C   . GLY B 1 246 ? 192.356 156.602 209.102 1.00 32.93  ? 267 GLY B C   1 
ATOM   5345  O O   . GLY B 1 246 ? 191.866 157.652 209.532 1.00 32.93  ? 267 GLY B O   1 
ATOM   5346  N N   . HIS B 1 247 ? 191.943 155.982 207.988 1.00 29.25  ? 268 HIS B N   1 
ATOM   5347  C CA  . HIS B 1 247 ? 190.927 156.486 207.055 1.00 29.25  ? 268 HIS B CA  1 
ATOM   5348  C C   . HIS B 1 247 ? 191.276 157.888 206.551 1.00 29.25  ? 268 HIS B C   1 
ATOM   5349  O O   . HIS B 1 247 ? 190.548 158.856 206.772 1.00 29.25  ? 268 HIS B O   1 
ATOM   5350  C CB  . HIS B 1 247 ? 189.523 156.457 207.676 1.00 29.25  ? 268 HIS B CB  1 
ATOM   5351  C CG  . HIS B 1 247 ? 189.231 155.218 208.461 1.00 29.25  ? 268 HIS B CG  1 
ATOM   5352  N ND1 . HIS B 1 247 ? 188.748 154.066 207.879 1.00 29.25  ? 268 HIS B ND1 1 
ATOM   5353  C CD2 . HIS B 1 247 ? 189.351 154.950 209.782 1.00 29.25  ? 268 HIS B CD2 1 
ATOM   5354  C CE1 . HIS B 1 247 ? 188.583 153.142 208.808 1.00 29.25  ? 268 HIS B CE1 1 
ATOM   5355  N NE2 . HIS B 1 247 ? 188.943 153.653 209.972 1.00 29.25  ? 268 HIS B NE2 1 
ATOM   5356  N N   . TYR B 1 248 ? 192.413 157.985 205.866 1.00 28.73  ? 269 TYR B N   1 
ATOM   5357  C CA  . TYR B 1 248 ? 192.873 159.272 205.367 1.00 28.73  ? 269 TYR B CA  1 
ATOM   5358  C C   . TYR B 1 248 ? 193.378 159.133 203.938 1.00 28.73  ? 269 TYR B C   1 
ATOM   5359  O O   . TYR B 1 248 ? 193.676 158.036 203.458 1.00 28.73  ? 269 TYR B O   1 
ATOM   5360  C CB  . TYR B 1 248 ? 193.959 159.890 206.267 1.00 28.73  ? 269 TYR B CB  1 
ATOM   5361  C CG  . TYR B 1 248 ? 195.244 159.101 206.398 1.00 28.73  ? 269 TYR B CG  1 
ATOM   5362  C CD1 . TYR B 1 248 ? 195.365 158.084 207.338 1.00 28.73  ? 269 TYR B CD1 1 
ATOM   5363  C CD2 . TYR B 1 248 ? 196.350 159.402 205.612 1.00 28.73  ? 269 TYR B CD2 1 
ATOM   5364  C CE1 . TYR B 1 248 ? 196.542 157.370 207.470 1.00 28.73  ? 269 TYR B CE1 1 
ATOM   5365  C CE2 . TYR B 1 248 ? 197.530 158.694 205.736 1.00 28.73  ? 269 TYR B CE2 1 
ATOM   5366  C CZ  . TYR B 1 248 ? 197.620 157.682 206.668 1.00 28.73  ? 269 TYR B CZ  1 
ATOM   5367  O OH  . TYR B 1 248 ? 198.792 156.974 206.796 1.00 28.73  ? 269 TYR B OH  1 
ATOM   5368  N N   . LEU B 1 249 ? 193.432 160.272 203.255 1.00 49.69  ? 270 LEU B N   1 
ATOM   5369  C CA  . LEU B 1 249 ? 193.857 160.354 201.867 1.00 49.69  ? 270 LEU B CA  1 
ATOM   5370  C C   . LEU B 1 249 ? 195.049 161.291 201.770 1.00 49.69  ? 270 LEU B C   1 
ATOM   5371  O O   . LEU B 1 249 ? 194.984 162.434 202.233 1.00 49.69  ? 270 LEU B O   1 
ATOM   5372  C CB  . LEU B 1 249 ? 192.728 160.858 200.959 1.00 49.69  ? 270 LEU B CB  1 
ATOM   5373  C CG  . LEU B 1 249 ? 191.594 159.939 200.490 1.00 49.69  ? 270 LEU B CG  1 
ATOM   5374  C CD1 . LEU B 1 249 ? 190.601 159.602 201.594 1.00 49.69  ? 270 LEU B CD1 1 
ATOM   5375  C CD2 . LEU B 1 249 ? 190.878 160.572 199.309 1.00 49.69  ? 270 LEU B CD2 1 
ATOM   5376  N N   . ILE B 1 250 ? 196.128 160.812 201.166 1.00 25.72  ? 271 ILE B N   1 
ATOM   5377  C CA  . ILE B 1 250 ? 197.283 161.648 200.872 1.00 25.72  ? 271 ILE B CA  1 
ATOM   5378  C C   . ILE B 1 250 ? 197.114 162.165 199.453 1.00 25.72  ? 271 ILE B C   1 
ATOM   5379  O O   . ILE B 1 250 ? 196.966 161.373 198.513 1.00 25.72  ? 271 ILE B O   1 
ATOM   5380  C CB  . ILE B 1 250 ? 198.597 160.872 201.027 1.00 25.72  ? 271 ILE B CB  1 
ATOM   5381  C CG1 . ILE B 1 250 ? 198.647 160.173 202.384 1.00 25.72  ? 271 ILE B CG1 1 
ATOM   5382  C CG2 . ILE B 1 250 ? 199.783 161.806 200.866 1.00 25.72  ? 271 ILE B CG2 1 
ATOM   5383  C CD1 . ILE B 1 250 ? 199.892 159.348 202.599 1.00 25.72  ? 271 ILE B CD1 1 
ATOM   5384  N N   . LEU B 1 251 ? 197.136 163.489 199.307 1.00 20.24  ? 272 LEU B N   1 
ATOM   5385  C CA  . LEU B 1 251 ? 196.817 164.193 198.077 1.00 20.24  ? 272 LEU B CA  1 
ATOM   5386  C C   . LEU B 1 251 ? 198.008 165.051 197.675 1.00 20.24  ? 272 LEU B C   1 
ATOM   5387  O O   . LEU B 1 251 ? 198.728 165.567 198.535 1.00 20.24  ? 272 LEU B O   1 
ATOM   5388  C CB  . LEU B 1 251 ? 195.580 165.074 198.280 1.00 20.24  ? 272 LEU B CB  1 
ATOM   5389  C CG  . LEU B 1 251 ? 194.799 165.615 197.087 1.00 20.24  ? 272 LEU B CG  1 
ATOM   5390  C CD1 . LEU B 1 251 ? 193.879 164.548 196.549 1.00 20.24  ? 272 LEU B CD1 1 
ATOM   5391  C CD2 . LEU B 1 251 ? 194.005 166.839 197.494 1.00 20.24  ? 272 LEU B CD2 1 
ATOM   5392  N N   . ARG B 1 252 ? 198.226 165.195 196.371 1.00 23.19  ? 273 ARG B N   1 
ATOM   5393  C CA  . ARG B 1 252 ? 199.324 165.997 195.843 1.00 23.19  ? 273 ARG B CA  1 
ATOM   5394  C C   . ARG B 1 252 ? 198.753 167.055 194.913 1.00 23.19  ? 273 ARG B C   1 
ATOM   5395  O O   . ARG B 1 252 ? 198.061 166.722 193.946 1.00 23.19  ? 273 ARG B O   1 
ATOM   5396  C CB  . ARG B 1 252 ? 200.337 165.122 195.105 1.00 23.19  ? 273 ARG B CB  1 
ATOM   5397  C CG  . ARG B 1 252 ? 201.330 165.904 194.269 1.00 23.19  ? 273 ARG B CG  1 
ATOM   5398  C CD  . ARG B 1 252 ? 202.519 165.046 193.880 1.00 23.19  ? 273 ARG B CD  1 
ATOM   5399  N NE  . ARG B 1 252 ? 203.441 164.866 194.994 1.00 23.19  ? 273 ARG B NE  1 
ATOM   5400  C CZ  . ARG B 1 252 ? 204.655 164.344 194.886 1.00 23.19  ? 273 ARG B CZ  1 
ATOM   5401  N NH1 . ARG B 1 252 ? 205.139 163.957 193.717 1.00 23.19  ? 273 ARG B NH1 1 
ATOM   5402  N NH2 . ARG B 1 252 ? 205.404 164.211 195.977 1.00 23.19  ? 273 ARG B NH2 1 
ATOM   5403  N N   . VAL B 1 253 ? 199.048 168.325 195.196 1.00 29.29  ? 274 VAL B N   1 
ATOM   5404  C CA  . VAL B 1 253 ? 198.524 169.429 194.405 1.00 29.29  ? 274 VAL B CA  1 
ATOM   5405  C C   . VAL B 1 253 ? 199.678 170.139 193.712 1.00 29.29  ? 274 VAL B C   1 
ATOM   5406  O O   . VAL B 1 253 ? 200.841 170.044 194.117 1.00 29.29  ? 274 VAL B O   1 
ATOM   5407  C CB  . VAL B 1 253 ? 197.711 170.426 195.254 1.00 29.29  ? 274 VAL B CB  1 
ATOM   5408  C CG1 . VAL B 1 253 ? 196.475 169.756 195.822 1.00 29.29  ? 274 VAL B CG1 1 
ATOM   5409  C CG2 . VAL B 1 253 ? 198.565 170.983 196.364 1.00 29.29  ? 274 VAL B CG2 1 
ATOM   5410  N N   . ASN B 1 254 ? 199.336 170.859 192.647 1.00 33.93  ? 275 ASN B N   1 
ATOM   5411  C CA  . ASN B 1 254 ? 200.298 171.600 191.842 1.00 33.93  ? 275 ASN B CA  1 
ATOM   5412  C C   . ASN B 1 254 ? 200.131 173.088 192.114 1.00 33.93  ? 275 ASN B C   1 
ATOM   5413  O O   . ASN B 1 254 ? 199.047 173.643 191.905 1.00 33.93  ? 275 ASN B O   1 
ATOM   5414  C CB  . ASN B 1 254 ? 200.110 171.311 190.353 1.00 33.93  ? 275 ASN B CB  1 
ATOM   5415  C CG  . ASN B 1 254 ? 199.960 169.834 190.059 1.00 33.93  ? 275 ASN B CG  1 
ATOM   5416  O OD1 . ASN B 1 254 ? 198.901 169.381 189.627 1.00 33.93  ? 275 ASN B OD1 1 
ATOM   5417  N ND2 . ASN B 1 254 ? 201.023 169.074 190.287 1.00 33.93  ? 275 ASN B ND2 1 
ATOM   5418  N N   . ILE B 1 255 ? 201.201 173.727 192.573 1.00 39.34  ? 276 ILE B N   1 
ATOM   5419  C CA  . ILE B 1 255 ? 201.223 175.178 192.725 1.00 39.34  ? 276 ILE B CA  1 
ATOM   5420  C C   . ILE B 1 255 ? 201.377 175.784 191.336 1.00 39.34  ? 276 ILE B C   1 
ATOM   5421  O O   . ILE B 1 255 ? 202.353 175.479 190.636 1.00 39.34  ? 276 ILE B O   1 
ATOM   5422  C CB  . ILE B 1 255 ? 202.351 175.629 193.665 1.00 39.34  ? 276 ILE B CB  1 
ATOM   5423  C CG1 . ILE B 1 255 ? 202.107 175.108 195.080 1.00 39.34  ? 276 ILE B CG1 1 
ATOM   5424  C CG2 . ILE B 1 255 ? 202.477 177.142 193.669 1.00 39.34  ? 276 ILE B CG2 1 
ATOM   5425  C CD1 . ILE B 1 255 ? 203.361 175.020 195.913 1.00 39.34  ? 276 ILE B CD1 1 
ATOM   5426  N N   . PRO B 1 256 ? 200.455 176.630 190.892 1.00 42.80  ? 277 PRO B N   1 
ATOM   5427  C CA  . PRO B 1 256 ? 200.523 177.153 189.527 1.00 42.80  ? 277 PRO B CA  1 
ATOM   5428  C C   . PRO B 1 256 ? 201.532 178.288 189.404 1.00 42.80  ? 277 PRO B C   1 
ATOM   5429  O O   . PRO B 1 256 ? 201.951 178.906 190.382 1.00 42.80  ? 277 PRO B O   1 
ATOM   5430  C CB  . PRO B 1 256 ? 199.098 177.651 189.273 1.00 42.80  ? 277 PRO B CB  1 
ATOM   5431  C CG  . PRO B 1 256 ? 198.592 178.031 190.621 1.00 42.80  ? 277 PRO B CG  1 
ATOM   5432  C CD  . PRO B 1 256 ? 199.319 177.190 191.645 1.00 42.80  ? 277 PRO B CD  1 
ATOM   5433  N N   . ASP B 1 257 ? 201.919 178.547 188.158 1.00 53.51  ? 278 ASP B N   1 
ATOM   5434  C CA  . ASP B 1 257 ? 202.787 179.666 187.821 1.00 53.51  ? 278 ASP B CA  1 
ATOM   5435  C C   . ASP B 1 257 ? 202.358 180.188 186.460 1.00 53.51  ? 278 ASP B C   1 
ATOM   5436  O O   . ASP B 1 257 ? 202.209 179.408 185.516 1.00 53.51  ? 278 ASP B O   1 
ATOM   5437  C CB  . ASP B 1 257 ? 204.260 179.248 187.804 1.00 53.51  ? 278 ASP B CB  1 
ATOM   5438  C CG  . ASP B 1 257 ? 205.200 180.429 187.680 1.00 53.51  ? 278 ASP B CG  1 
ATOM   5439  O OD1 . ASP B 1 257 ? 204.799 181.551 188.057 1.00 53.51  ? 278 ASP B OD1 1 
ATOM   5440  O OD2 . ASP B 1 257 ? 206.339 180.237 187.206 1.00 53.51  ? 278 ASP B OD2 1 
ATOM   5441  N N   . LEU B 1 258 ? 202.147 181.496 186.364 1.00 43.37  ? 279 LEU B N   1 
ATOM   5442  C CA  . LEU B 1 258 ? 201.615 182.105 185.150 1.00 43.37  ? 279 LEU B CA  1 
ATOM   5443  C C   . LEU B 1 258 ? 202.775 182.562 184.274 1.00 43.37  ? 279 LEU B C   1 
ATOM   5444  O O   . LEU B 1 258 ? 203.492 183.504 184.623 1.00 43.37  ? 279 LEU B O   1 
ATOM   5445  C CB  . LEU B 1 258 ? 200.694 183.271 185.498 1.00 43.37  ? 279 LEU B CB  1 
ATOM   5446  C CG  . LEU B 1 258 ? 199.467 182.915 186.339 1.00 43.37  ? 279 LEU B CG  1 
ATOM   5447  C CD1 . LEU B 1 258 ? 198.645 184.156 186.647 1.00 43.37  ? 279 LEU B CD1 1 
ATOM   5448  C CD2 . LEU B 1 258 ? 198.619 181.866 185.637 1.00 43.37  ? 279 LEU B CD2 1 
ATOM   5449  N N   . ILE B 1 259 ? 202.958 181.897 183.137 1.00 47.01  ? 280 ILE B N   1 
ATOM   5450  C CA  . ILE B 1 259 ? 203.973 182.277 182.165 1.00 47.01  ? 280 ILE B CA  1 
ATOM   5451  C C   . ILE B 1 259 ? 203.266 183.021 181.040 1.00 47.01  ? 280 ILE B C   1 
ATOM   5452  O O   . ILE B 1 259 ? 202.050 182.890 180.845 1.00 47.01  ? 280 ILE B O   1 
ATOM   5453  C CB  . ILE B 1 259 ? 204.755 181.037 181.664 1.00 47.01  ? 280 ILE B CB  1 
ATOM   5454  C CG1 . ILE B 1 259 ? 206.118 181.427 181.083 1.00 47.01  ? 280 ILE B CG1 1 
ATOM   5455  C CG2 . ILE B 1 259 ? 203.949 180.237 180.647 1.00 47.01  ? 280 ILE B CG2 1 
ATOM   5456  C CD1 . ILE B 1 259 ? 207.077 181.996 182.105 1.00 47.01  ? 280 ILE B CD1 1 
ATOM   5457  N N   . GLU B 1 260 ? 204.011 183.863 180.333 1.00 46.47  ? 281 GLU B N   1 
ATOM   5458  C CA  . GLU B 1 260 ? 203.469 184.671 179.250 1.00 46.47  ? 281 GLU B CA  1 
ATOM   5459  C C   . GLU B 1 260 ? 203.994 184.140 177.924 1.00 46.47  ? 281 GLU B C   1 
ATOM   5460  O O   . GLU B 1 260 ? 205.210 184.013 177.741 1.00 46.47  ? 281 GLU B O   1 
ATOM   5461  C CB  . GLU B 1 260 ? 203.844 186.142 179.430 1.00 46.47  ? 281 GLU B CB  1 
ATOM   5462  C CG  . GLU B 1 260 ? 203.707 186.973 178.172 1.00 46.47  ? 281 GLU B CG  1 
ATOM   5463  C CD  . GLU B 1 260 ? 203.731 188.459 178.447 1.00 46.47  ? 281 GLU B CD  1 
ATOM   5464  O OE1 . GLU B 1 260 ? 203.719 188.844 179.635 1.00 46.47  ? 281 GLU B OE1 1 
ATOM   5465  O OE2 . GLU B 1 260 ? 203.771 189.241 177.475 1.00 46.47  ? 281 GLU B OE2 1 
ATOM   5466  N N   . VAL B 1 261 ? 203.082 183.816 177.017 1.00 48.93  ? 282 VAL B N   1 
ATOM   5467  C CA  . VAL B 1 261 ? 203.479 183.496 175.642 1.00 48.93  ? 282 VAL B CA  1 
ATOM   5468  C C   . VAL B 1 261 ? 203.984 184.767 174.956 1.00 48.93  ? 282 VAL B C   1 
ATOM   5469  O O   . VAL B 1 261 ? 203.359 185.837 175.087 1.00 48.93  ? 282 VAL B O   1 
ATOM   5470  C CB  . VAL B 1 261 ? 202.308 182.817 174.888 1.00 48.93  ? 282 VAL B CB  1 
ATOM   5471  C CG1 . VAL B 1 261 ? 201.047 183.680 174.809 1.00 48.93  ? 282 VAL B CG1 1 
ATOM   5472  C CG2 . VAL B 1 261 ? 202.725 182.373 173.490 1.00 48.93  ? 282 VAL B CG2 1 
ATOM   5473  N N   . PRO B 1 262 ? 205.160 184.743 174.325 1.00 57.43  ? 283 PRO B N   1 
ATOM   5474  C CA  . PRO B 1 262 ? 205.754 185.996 173.843 1.00 57.43  ? 283 PRO B CA  1 
ATOM   5475  C C   . PRO B 1 262 ? 205.097 186.515 172.573 1.00 57.43  ? 283 PRO B C   1 
ATOM   5476  O O   . PRO B 1 262 ? 204.830 185.766 171.630 1.00 57.43  ? 283 PRO B O   1 
ATOM   5477  C CB  . PRO B 1 262 ? 207.222 185.626 173.592 1.00 57.43  ? 283 PRO B CB  1 
ATOM   5478  C CG  . PRO B 1 262 ? 207.246 184.157 173.453 1.00 57.43  ? 283 PRO B CG  1 
ATOM   5479  C CD  . PRO B 1 262 ? 206.091 183.604 174.221 1.00 57.43  ? 283 PRO B CD  1 
ATOM   5480  N N   . GLY B 1 263 ? 204.848 187.821 172.566 1.00 64.60  ? 284 GLY B N   1 
ATOM   5481  C CA  . GLY B 1 263 ? 204.329 188.520 171.402 1.00 64.60  ? 284 GLY B CA  1 
ATOM   5482  C C   . GLY B 1 263 ? 202.917 188.164 170.993 1.00 64.60  ? 284 GLY B C   1 
ATOM   5483  O O   . GLY B 1 263 ? 202.628 188.086 169.793 1.00 64.60  ? 284 GLY B O   1 
ATOM   5484  N N   . ALA B 1 264 ? 202.023 187.957 171.956 1.00 54.00  ? 285 ALA B N   1 
ATOM   5485  C CA  . ALA B 1 264 ? 200.632 187.631 171.676 1.00 54.00  ? 285 ALA B CA  1 
ATOM   5486  C C   . ALA B 1 264 ? 199.733 188.716 172.246 1.00 54.00  ? 285 ALA B C   1 
ATOM   5487  O O   . ALA B 1 264 ? 199.845 189.064 173.426 1.00 54.00  ? 285 ALA B O   1 
ATOM   5488  C CB  . ALA B 1 264 ? 200.252 186.270 172.257 1.00 54.00  ? 285 ALA B CB  1 
ATOM   5489  N N   . VAL B 1 265 ? 198.845 189.244 171.408 1.00 47.18  ? 286 VAL B N   1 
ATOM   5490  C CA  . VAL B 1 265 ? 197.919 190.304 171.786 1.00 47.18  ? 286 VAL B CA  1 
ATOM   5491  C C   . VAL B 1 265 ? 196.501 189.811 171.529 1.00 47.18  ? 286 VAL B C   1 
ATOM   5492  O O   . VAL B 1 265 ? 196.184 189.367 170.419 1.00 47.18  ? 286 VAL B O   1 
ATOM   5493  C CB  . VAL B 1 265 ? 198.200 191.605 171.009 1.00 47.18  ? 286 VAL B CB  1 
ATOM   5494  C CG1 . VAL B 1 265 ? 197.134 192.650 171.300 1.00 47.18  ? 286 VAL B CG1 1 
ATOM   5495  C CG2 . VAL B 1 265 ? 199.580 192.147 171.354 1.00 47.18  ? 286 VAL B CG2 1 
ATOM   5496  N N   . ILE B 1 266 ? 195.658 189.877 172.554 1.00 38.71  ? 287 ILE B N   1 
ATOM   5497  C CA  . ILE B 1 266 ? 194.247 189.541 172.423 1.00 38.71  ? 287 ILE B CA  1 
ATOM   5498  C C   . ILE B 1 266 ? 193.479 190.819 172.119 1.00 38.71  ? 287 ILE B C   1 
ATOM   5499  O O   . ILE B 1 266 ? 193.586 191.808 172.853 1.00 38.71  ? 287 ILE B O   1 
ATOM   5500  C CB  . ILE B 1 266 ? 193.719 188.867 173.699 1.00 38.71  ? 287 ILE B CB  1 
ATOM   5501  C CG1 . ILE B 1 266 ? 194.645 187.726 174.119 1.00 38.71  ? 287 ILE B CG1 1 
ATOM   5502  C CG2 . ILE B 1 266 ? 192.306 188.354 173.483 1.00 38.71  ? 287 ILE B CG2 1 
ATOM   5503  C CD1 . ILE B 1 266 ? 194.728 186.601 173.114 1.00 38.71  ? 287 ILE B CD1 1 
ATOM   5504  N N   . GLN B 1 267 ? 192.707 190.802 171.037 1.00 38.02  ? 288 GLN B N   1 
ATOM   5505  C CA  . GLN B 1 267 ? 191.994 191.971 170.548 1.00 38.02  ? 288 GLN B CA  1 
ATOM   5506  C C   . GLN B 1 267 ? 190.496 191.740 170.676 1.00 38.02  ? 288 GLN B C   1 
ATOM   5507  O O   . GLN B 1 267 ? 189.980 190.709 170.225 1.00 38.02  ? 288 GLN B O   1 
ATOM   5508  C CB  . GLN B 1 267 ? 192.360 192.259 169.091 1.00 38.02  ? 288 GLN B CB  1 
ATOM   5509  C CG  . GLN B 1 267 ? 191.945 193.633 168.609 1.00 38.02  ? 288 GLN B CG  1 
ATOM   5510  C CD  . GLN B 1 267 ? 192.560 194.741 169.434 1.00 38.02  ? 288 GLN B CD  1 
ATOM   5511  O OE1 . GLN B 1 267 ? 191.856 195.590 169.979 1.00 38.02  ? 288 GLN B OE1 1 
ATOM   5512  N NE2 . GLN B 1 267 ? 193.884 194.742 169.528 1.00 38.02  ? 288 GLN B NE2 1 
ATOM   5513  N N   . GLU B 1 268 ? 189.809 192.697 171.290 1.00 43.37  ? 289 GLU B N   1 
ATOM   5514  C CA  . GLU B 1 268 ? 188.364 192.679 171.441 1.00 43.37  ? 289 GLU B CA  1 
ATOM   5515  C C   . GLU B 1 268 ? 187.720 193.625 170.435 1.00 43.37  ? 289 GLU B C   1 
ATOM   5516  O O   . GLU B 1 268 ? 188.332 194.591 169.974 1.00 43.37  ? 289 GLU B O   1 
ATOM   5517  C CB  . GLU B 1 268 ? 187.960 193.074 172.863 1.00 43.37  ? 289 GLU B CB  1 
ATOM   5518  C CG  . GLU B 1 268 ? 188.723 192.345 173.951 1.00 43.37  ? 289 GLU B CG  1 
ATOM   5519  C CD  . GLU B 1 268 ? 187.892 191.271 174.621 1.00 43.37  ? 289 GLU B CD  1 
ATOM   5520  O OE1 . GLU B 1 268 ? 186.789 190.974 174.119 1.00 43.37  ? 289 GLU B OE1 1 
ATOM   5521  O OE2 . GLU B 1 268 ? 188.340 190.727 175.652 1.00 43.37  ? 289 GLU B OE2 1 
ATOM   5522  N N   . PHE B 1 269 ? 186.467 193.333 170.096 1.00 46.67  ? 290 PHE B N   1 
ATOM   5523  C CA  . PHE B 1 269 ? 185.738 194.120 169.114 1.00 46.67  ? 290 PHE B CA  1 
ATOM   5524  C C   . PHE B 1 269 ? 184.349 194.447 169.636 1.00 46.67  ? 290 PHE B C   1 
ATOM   5525  O O   . PHE B 1 269 ? 183.729 193.639 170.333 1.00 46.67  ? 290 PHE B O   1 
ATOM   5526  C CB  . PHE B 1 269 ? 185.632 193.380 167.776 1.00 46.67  ? 290 PHE B CB  1 
ATOM   5527  C CG  . PHE B 1 269 ? 186.906 193.378 166.988 1.00 46.67  ? 290 PHE B CG  1 
ATOM   5528  C CD1 . PHE B 1 269 ? 187.396 194.552 166.437 1.00 46.67  ? 290 PHE B CD1 1 
ATOM   5529  C CD2 . PHE B 1 269 ? 187.619 192.205 166.805 1.00 46.67  ? 290 PHE B CD2 1 
ATOM   5530  C CE1 . PHE B 1 269 ? 188.573 194.556 165.712 1.00 46.67  ? 290 PHE B CE1 1 
ATOM   5531  C CE2 . PHE B 1 269 ? 188.798 192.201 166.083 1.00 46.67  ? 290 PHE B CE2 1 
ATOM   5532  C CZ  . PHE B 1 269 ? 189.275 193.378 165.534 1.00 46.67  ? 290 PHE B CZ  1 
ATOM   5533  N N   . ILE B 1 270 ? 183.870 195.639 169.292 1.00 48.43  ? 291 ILE B N   1 
ATOM   5534  C CA  . ILE B 1 270 ? 182.522 196.083 169.614 1.00 48.43  ? 291 ILE B CA  1 
ATOM   5535  C C   . ILE B 1 270 ? 181.705 196.063 168.332 1.00 48.43  ? 291 ILE B C   1 
ATOM   5536  O O   . ILE B 1 270 ? 182.125 196.620 167.308 1.00 48.43  ? 291 ILE B O   1 
ATOM   5537  C CB  . ILE B 1 270 ? 182.532 197.487 170.243 1.00 48.43  ? 291 ILE B CB  1 
ATOM   5538  C CG1 . ILE B 1 270 ? 183.506 197.535 171.421 1.00 48.43  ? 291 ILE B CG1 1 
ATOM   5539  C CG2 . ILE B 1 270 ? 181.136 197.885 170.691 1.00 48.43  ? 291 ILE B CG2 1 
ATOM   5540  C CD1 . ILE B 1 270 ? 183.711 198.921 171.985 1.00 48.43  ? 291 ILE B CD1 1 
ATOM   5541  N N   . LYS B 1 271 ? 180.548 195.411 168.378 1.00 42.89  ? 292 LYS B N   1 
ATOM   5542  C CA  . LYS B 1 271 ? 179.673 195.278 167.223 1.00 42.89  ? 292 LYS B CA  1 
ATOM   5543  C C   . LYS B 1 271 ? 178.458 196.175 167.404 1.00 42.89  ? 292 LYS B C   1 
ATOM   5544  O O   . LYS B 1 271 ? 177.766 196.093 168.424 1.00 42.89  ? 292 LYS B O   1 
ATOM   5545  C CB  . LYS B 1 271 ? 179.237 193.824 167.034 1.00 42.89  ? 292 LYS B CB  1 
ATOM   5546  C CG  . LYS B 1 271 ? 180.375 192.879 166.694 1.00 42.89  ? 292 LYS B CG  1 
ATOM   5547  C CD  . LYS B 1 271 ? 179.854 191.509 166.299 1.00 42.89  ? 292 LYS B CD  1 
ATOM   5548  C CE  . LYS B 1 271 ? 179.304 190.762 167.500 1.00 42.89  ? 292 LYS B CE  1 
ATOM   5549  N NZ  . LYS B 1 271 ? 178.859 189.389 167.138 1.00 42.89  ? 292 LYS B NZ  1 
ATOM   5550  N N   . ILE B 1 272 ? 178.204 197.028 166.415 1.00 51.71  ? 293 ILE B N   1 
ATOM   5551  C CA  . ILE B 1 272 ? 177.051 197.915 166.419 1.00 51.71  ? 293 ILE B CA  1 
ATOM   5552  C C   . ILE B 1 272 ? 176.157 197.549 165.243 1.00 51.71  ? 293 ILE B C   1 
ATOM   5553  O O   . ILE B 1 272 ? 176.562 196.845 164.314 1.00 51.71  ? 293 ILE B O   1 
ATOM   5554  C CB  . ILE B 1 272 ? 177.453 199.403 166.357 1.00 51.71  ? 293 ILE B CB  1 
ATOM   5555  C CG1 . ILE B 1 272 ? 178.111 199.725 165.014 1.00 51.71  ? 293 ILE B CG1 1 
ATOM   5556  C CG2 . ILE B 1 272 ? 178.370 199.758 167.519 1.00 51.71  ? 293 ILE B CG2 1 
ATOM   5557  C CD1 . ILE B 1 272 ? 178.579 201.159 164.888 1.00 51.71  ? 293 ILE B CD1 1 
ATOM   5558  N N   . GLY B 1 273 ? 174.921 198.032 165.296 1.00 55.73  ? 294 GLY B N   1 
ATOM   5559  C CA  . GLY B 1 273 ? 173.941 197.771 164.256 1.00 55.73  ? 294 GLY B CA  1 
ATOM   5560  C C   . GLY B 1 273 ? 173.857 198.935 163.283 1.00 55.73  ? 294 GLY B C   1 
ATOM   5561  O O   . GLY B 1 273 ? 173.844 200.097 163.688 1.00 55.73  ? 294 GLY B O   1 
ATOM   5562  N N   . TYR B 1 274 ? 173.802 198.606 161.997 1.00 57.68  ? 295 TYR B N   1 
ATOM   5563  C CA  . TYR B 1 274 ? 173.715 199.606 160.946 1.00 57.68  ? 295 TYR B CA  1 
ATOM   5564  C C   . TYR B 1 274 ? 172.434 199.409 160.146 1.00 57.68  ? 295 TYR B C   1 
ATOM   5565  O O   . TYR B 1 274 ? 171.943 198.287 159.989 1.00 57.68  ? 295 TYR B O   1 
ATOM   5566  C CB  . TYR B 1 274 ? 174.945 199.568 160.017 1.00 57.68  ? 295 TYR B CB  1 
ATOM   5567  C CG  . TYR B 1 274 ? 175.122 198.304 159.200 1.00 57.68  ? 295 TYR B CG  1 
ATOM   5568  C CD1 . TYR B 1 274 ? 175.734 197.180 159.743 1.00 57.68  ? 295 TYR B CD1 1 
ATOM   5569  C CD2 . TYR B 1 274 ? 174.711 198.249 157.871 1.00 57.68  ? 295 TYR B CD2 1 
ATOM   5570  C CE1 . TYR B 1 274 ? 175.908 196.028 158.994 1.00 57.68  ? 295 TYR B CE1 1 
ATOM   5571  C CE2 . TYR B 1 274 ? 174.880 197.102 157.116 1.00 57.68  ? 295 TYR B CE2 1 
ATOM   5572  C CZ  . TYR B 1 274 ? 175.480 195.997 157.682 1.00 57.68  ? 295 TYR B CZ  1 
ATOM   5573  O OH  . TYR B 1 274 ? 175.651 194.856 156.933 1.00 57.68  ? 295 TYR B OH  1 
ATOM   5574  N N   . ASN B 1 275 ? 171.896 200.518 159.645 1.00 61.66  ? 296 ASN B N   1 
ATOM   5575  C CA  . ASN B 1 275 ? 170.633 200.526 158.916 1.00 61.66  ? 296 ASN B CA  1 
ATOM   5576  C C   . ASN B 1 275 ? 170.928 200.450 157.422 1.00 61.66  ? 296 ASN B C   1 
ATOM   5577  O O   . ASN B 1 275 ? 171.459 201.400 156.837 1.00 61.66  ? 296 ASN B O   1 
ATOM   5578  C CB  . ASN B 1 275 ? 169.823 201.775 159.256 1.00 61.66  ? 296 ASN B CB  1 
ATOM   5579  C CG  . ASN B 1 275 ? 168.353 201.627 158.919 1.00 61.66  ? 296 ASN B CG  1 
ATOM   5580  O OD1 . ASN B 1 275 ? 167.925 200.609 158.377 1.00 61.66  ? 296 ASN B OD1 1 
ATOM   5581  N ND2 . ASN B 1 275 ? 167.568 202.647 159.245 1.00 61.66  ? 296 ASN B ND2 1 
ATOM   5582  N N   . PHE B 1 276 ? 170.583 199.320 156.810 1.00 65.28  ? 297 PHE B N   1 
ATOM   5583  C CA  . PHE B 1 276 ? 170.746 199.123 155.379 1.00 65.28  ? 297 PHE B CA  1 
ATOM   5584  C C   . PHE B 1 276 ? 169.546 198.357 154.846 1.00 65.28  ? 297 PHE B C   1 
ATOM   5585  O O   . PHE B 1 276 ? 169.034 197.451 155.512 1.00 65.28  ? 297 PHE B O   1 
ATOM   5586  C CB  . PHE B 1 276 ? 172.042 198.368 155.057 1.00 65.28  ? 297 PHE B CB  1 
ATOM   5587  C CG  . PHE B 1 276 ? 172.283 198.176 153.587 1.00 65.28  ? 297 PHE B CG  1 
ATOM   5588  C CD1 . PHE B 1 276 ? 172.679 199.241 152.793 1.00 65.28  ? 297 PHE B CD1 1 
ATOM   5589  C CD2 . PHE B 1 276 ? 172.115 196.931 153.000 1.00 65.28  ? 297 PHE B CD2 1 
ATOM   5590  C CE1 . PHE B 1 276 ? 172.903 199.069 151.437 1.00 65.28  ? 297 PHE B CE1 1 
ATOM   5591  C CE2 . PHE B 1 276 ? 172.337 196.750 151.646 1.00 65.28  ? 297 PHE B CE2 1 
ATOM   5592  C CZ  . PHE B 1 276 ? 172.731 197.821 150.864 1.00 65.28  ? 297 PHE B CZ  1 
ATOM   5593  N N   . GLY B 1 277 ? 169.090 198.745 153.654 1.00 67.49  ? 298 GLY B N   1 
ATOM   5594  C CA  . GLY B 1 277 ? 167.972 198.085 153.003 1.00 67.49  ? 298 GLY B CA  1 
ATOM   5595  C C   . GLY B 1 277 ? 166.650 198.215 153.722 1.00 67.49  ? 298 GLY B C   1 
ATOM   5596  O O   . GLY B 1 277 ? 165.759 197.387 153.518 1.00 67.49  ? 298 GLY B O   1 
ATOM   5597  N N   . GLY B 1 278 ? 166.496 199.235 154.563 1.00 69.88  ? 299 GLY B N   1 
ATOM   5598  C CA  . GLY B 1 278 ? 165.332 199.317 155.419 1.00 69.88  ? 299 GLY B CA  1 
ATOM   5599  C C   . GLY B 1 278 ? 165.332 198.335 156.566 1.00 69.88  ? 299 GLY B C   1 
ATOM   5600  O O   . GLY B 1 278 ? 164.267 198.037 157.112 1.00 69.88  ? 299 GLY B O   1 
ATOM   5601  N N   . SER B 1 279 ? 166.499 197.818 156.952 1.00 73.77  ? 300 SER B N   1 
ATOM   5602  C CA  . SER B 1 279 ? 166.582 196.836 158.023 1.00 73.77  ? 300 SER B CA  1 
ATOM   5603  C C   . SER B 1 279 ? 167.835 197.081 158.851 1.00 73.77  ? 300 SER B C   1 
ATOM   5604  O O   . SER B 1 279 ? 168.758 197.782 158.433 1.00 73.77  ? 300 SER B O   1 
ATOM   5605  C CB  . SER B 1 279 ? 166.580 195.404 157.474 1.00 73.77  ? 300 SER B CB  1 
ATOM   5606  O OG  . SER B 1 279 ? 166.714 194.463 158.523 1.00 73.77  ? 300 SER B OG  1 
ATOM   5607  N N   . LEU B 1 280 ? 167.854 196.493 160.043 1.00 66.82  ? 301 LEU B N   1 
ATOM   5608  C CA  . LEU B 1 280 ? 168.975 196.624 160.964 1.00 66.82  ? 301 LEU B CA  1 
ATOM   5609  C C   . LEU B 1 280 ? 169.843 195.375 160.886 1.00 66.82  ? 301 LEU B C   1 
ATOM   5610  O O   . LEU B 1 280 ? 169.349 194.256 161.065 1.00 66.82  ? 301 LEU B O   1 
ATOM   5611  C CB  . LEU B 1 280 ? 168.481 196.842 162.395 1.00 66.82  ? 301 LEU B CB  1 
ATOM   5612  C CG  . LEU B 1 280 ? 169.417 197.584 163.352 1.00 66.82  ? 301 LEU B CG  1 
ATOM   5613  C CD1 . LEU B 1 280 ? 169.933 198.867 162.720 1.00 66.82  ? 301 LEU B CD1 1 
ATOM   5614  C CD2 . LEU B 1 280 ? 168.710 197.878 164.665 1.00 66.82  ? 301 LEU B CD2 1 
ATOM   5615  N N   . TRP B 1 281 ? 171.134 195.569 160.624 1.00 66.62  ? 302 TRP B N   1 
ATOM   5616  C CA  . TRP B 1 281 ? 172.058 194.466 160.419 1.00 66.62  ? 302 TRP B CA  1 
ATOM   5617  C C   . TRP B 1 281 ? 173.262 194.607 161.337 1.00 66.62  ? 302 TRP B C   1 
ATOM   5618  O O   . TRP B 1 281 ? 173.637 195.712 161.741 1.00 66.62  ? 302 TRP B O   1 
ATOM   5619  C CB  . TRP B 1 281 ? 172.541 194.387 158.961 1.00 66.62  ? 302 TRP B CB  1 
ATOM   5620  C CG  . TRP B 1 281 ? 171.441 194.339 157.947 1.00 66.62  ? 302 TRP B CG  1 
ATOM   5621  C CD1 . TRP B 1 281 ? 170.742 195.396 157.444 1.00 66.62  ? 302 TRP B CD1 1 
ATOM   5622  C CD2 . TRP B 1 281 ? 170.919 193.170 157.305 1.00 66.62  ? 302 TRP B CD2 1 
ATOM   5623  N NE1 . TRP B 1 281 ? 169.815 194.958 156.531 1.00 66.62  ? 302 TRP B NE1 1 
ATOM   5624  C CE2 . TRP B 1 281 ? 169.903 193.595 156.428 1.00 66.62  ? 302 TRP B CE2 1 
ATOM   5625  C CE3 . TRP B 1 281 ? 171.212 191.805 157.389 1.00 66.62  ? 302 TRP B CE3 1 
ATOM   5626  C CZ2 . TRP B 1 281 ? 169.177 192.705 155.640 1.00 66.62  ? 302 TRP B CZ2 1 
ATOM   5627  C CZ3 . TRP B 1 281 ? 170.490 190.923 156.606 1.00 66.62  ? 302 TRP B CZ3 1 
ATOM   5628  C CH2 . TRP B 1 281 ? 169.485 191.376 155.743 1.00 66.62  ? 302 TRP B CH2 1 
ATOM   5629  N N   . MET B 1 282 ? 173.862 193.465 161.658 1.00 62.58  ? 303 MET B N   1 
ATOM   5630  C CA  . MET B 1 282 ? 175.093 193.396 162.426 1.00 62.58  ? 303 MET B CA  1 
ATOM   5631  C C   . MET B 1 282 ? 176.109 192.532 161.692 1.00 62.58  ? 303 MET B C   1 
ATOM   5632  O O   . MET B 1 282 ? 175.736 191.528 161.072 1.00 62.58  ? 303 MET B O   1 
ATOM   5633  C CB  . MET B 1 282 ? 174.850 192.818 163.826 1.00 62.58  ? 303 MET B CB  1 
ATOM   5634  C CG  . MET B 1 282 ? 174.495 193.848 164.879 1.00 62.58  ? 303 MET B CG  1 
ATOM   5635  S SD  . MET B 1 282 ? 173.824 193.103 166.379 1.00 62.58  ? 303 MET B SD  1 
ATOM   5636  C CE  . MET B 1 282 ? 174.822 191.621 166.521 1.00 62.58  ? 303 MET B CE  1 
ATOM   5637  N N   . PRO B 1 283 ? 177.391 192.894 161.735 1.00 53.12  ? 304 PRO B N   1 
ATOM   5638  C CA  . PRO B 1 283 ? 178.415 192.038 161.129 1.00 53.12  ? 304 PRO B CA  1 
ATOM   5639  C C   . PRO B 1 283 ? 178.633 190.768 161.936 1.00 53.12  ? 304 PRO B C   1 
ATOM   5640  O O   . PRO B 1 283 ? 178.583 190.769 163.168 1.00 53.12  ? 304 PRO B O   1 
ATOM   5641  C CB  . PRO B 1 283 ? 179.668 192.920 161.136 1.00 53.12  ? 304 PRO B CB  1 
ATOM   5642  C CG  . PRO B 1 283 ? 179.428 193.911 162.214 1.00 53.12  ? 304 PRO B CG  1 
ATOM   5643  C CD  . PRO B 1 283 ? 177.952 194.162 162.230 1.00 53.12  ? 304 PRO B CD  1 
ATOM   5644  N N   . THR B 1 284 ? 178.883 189.673 161.218 1.00 59.94  ? 305 THR B N   1 
ATOM   5645  C CA  . THR B 1 284 ? 179.097 188.366 161.837 1.00 59.94  ? 305 THR B CA  1 
ATOM   5646  C C   . THR B 1 284 ? 180.600 188.123 161.945 1.00 59.94  ? 305 THR B C   1 
ATOM   5647  O O   . THR B 1 284 ? 181.206 187.403 161.151 1.00 59.94  ? 305 THR B O   1 
ATOM   5648  C CB  . THR B 1 284 ? 178.403 187.268 161.038 1.00 59.94  ? 305 THR B CB  1 
ATOM   5649  O OG1 . THR B 1 284 ? 179.011 187.158 159.745 1.00 59.94  ? 305 THR B OG1 1 
ATOM   5650  C CG2 . THR B 1 284 ? 176.926 187.586 160.871 1.00 59.94  ? 305 THR B CG2 1 
ATOM   5651  N N   . ILE B 1 285 ? 181.204 188.741 162.955 1.00 55.26  ? 306 ILE B N   1 
ATOM   5652  C CA  . ILE B 1 285 ? 182.631 188.588 163.222 1.00 55.26  ? 306 ILE B CA  1 
ATOM   5653  C C   . ILE B 1 285 ? 182.807 188.169 164.678 1.00 55.26  ? 306 ILE B C   1 
ATOM   5654  O O   . ILE B 1 285 ? 181.990 188.551 165.529 1.00 55.26  ? 306 ILE B O   1 
ATOM   5655  C CB  . ILE B 1 285 ? 183.400 189.883 162.903 1.00 55.26  ? 306 ILE B CB  1 
ATOM   5656  C CG1 . ILE B 1 285 ? 182.708 191.094 163.532 1.00 55.26  ? 306 ILE B CG1 1 
ATOM   5657  C CG2 . ILE B 1 285 ? 183.543 190.067 161.400 1.00 55.26  ? 306 ILE B CG2 1 
ATOM   5658  C CD1 . ILE B 1 285 ? 183.512 192.371 163.433 1.00 55.26  ? 306 ILE B CD1 1 
ATOM   5659  N N   . PRO B 1 286 ? 183.820 187.367 165.007 1.00 54.55  ? 307 PRO B N   1 
ATOM   5660  C CA  . PRO B 1 286 ? 184.038 186.997 166.410 1.00 54.55  ? 307 PRO B CA  1 
ATOM   5661  C C   . PRO B 1 286 ? 184.553 188.169 167.231 1.00 54.55  ? 307 PRO B C   1 
ATOM   5662  O O   . PRO B 1 286 ? 185.152 189.112 166.709 1.00 54.55  ? 307 PRO B O   1 
ATOM   5663  C CB  . PRO B 1 286 ? 185.082 185.878 166.326 1.00 54.55  ? 307 PRO B CB  1 
ATOM   5664  C CG  . PRO B 1 286 ? 185.769 186.101 165.028 1.00 54.55  ? 307 PRO B CG  1 
ATOM   5665  C CD  . PRO B 1 286 ? 184.724 186.637 164.102 1.00 54.55  ? 307 PRO B CD  1 
ATOM   5666  N N   . ASN B 1 287 ? 184.300 188.100 168.539 1.00 49.37  ? 308 ASN B N   1 
ATOM   5667  C CA  . ASN B 1 287 ? 184.705 189.174 169.438 1.00 49.37  ? 308 ASN B CA  1 
ATOM   5668  C C   . ASN B 1 287 ? 186.207 189.165 169.699 1.00 49.37  ? 308 ASN B C   1 
ATOM   5669  O O   . ASN B 1 287 ? 186.838 190.226 169.737 1.00 49.37  ? 308 ASN B O   1 
ATOM   5670  C CB  . ASN B 1 287 ? 183.943 189.065 170.758 1.00 49.37  ? 308 ASN B CB  1 
ATOM   5671  C CG  . ASN B 1 287 ? 182.451 189.255 170.587 1.00 49.37  ? 308 ASN B CG  1 
ATOM   5672  O OD1 . ASN B 1 287 ? 181.989 190.339 170.235 1.00 49.37  ? 308 ASN B OD1 1 
ATOM   5673  N ND2 . ASN B 1 287 ? 181.688 188.198 170.836 1.00 49.37  ? 308 ASN B ND2 1 
ATOM   5674  N N   . LYS B 1 288 ? 186.795 187.985 169.875 1.00 47.35  ? 309 LYS B N   1 
ATOM   5675  C CA  . LYS B 1 288 ? 188.177 187.845 170.314 1.00 47.35  ? 309 LYS B CA  1 
ATOM   5676  C C   . LYS B 1 288 ? 189.047 187.378 169.156 1.00 47.35  ? 309 LYS B C   1 
ATOM   5677  O O   . LYS B 1 288 ? 188.708 186.407 168.473 1.00 47.35  ? 309 LYS B O   1 
ATOM   5678  C CB  . LYS B 1 288 ? 188.271 186.851 171.473 1.00 47.35  ? 309 LYS B CB  1 
ATOM   5679  C CG  . LYS B 1 288 ? 187.651 187.347 172.764 1.00 47.35  ? 309 LYS B CG  1 
ATOM   5680  C CD  . LYS B 1 288 ? 187.510 186.221 173.770 1.00 47.35  ? 309 LYS B CD  1 
ATOM   5681  C CE  . LYS B 1 288 ? 186.577 185.139 173.254 1.00 47.35  ? 309 LYS B CE  1 
ATOM   5682  N NZ  . LYS B 1 288 ? 185.177 185.628 173.130 1.00 47.35  ? 309 LYS B NZ  1 
ATOM   5683  N N   . ILE B 1 289 ? 190.164 188.071 168.935 1.00 53.95  ? 310 ILE B N   1 
ATOM   5684  C CA  . ILE B 1 289 ? 191.143 187.686 167.921 1.00 53.95  ? 310 ILE B CA  1 
ATOM   5685  C C   . ILE B 1 289 ? 192.520 187.669 168.573 1.00 53.95  ? 310 ILE B C   1 
ATOM   5686  O O   . ILE B 1 289 ? 192.948 188.674 169.149 1.00 53.95  ? 310 ILE B O   1 
ATOM   5687  C CB  . ILE B 1 289 ? 191.128 188.637 166.711 1.00 53.95  ? 310 ILE B CB  1 
ATOM   5688  C CG1 . ILE B 1 289 ? 189.824 188.490 165.924 1.00 53.95  ? 310 ILE B CG1 1 
ATOM   5689  C CG2 . ILE B 1 289 ? 192.323 188.388 165.801 1.00 53.95  ? 310 ILE B CG2 1 
ATOM   5690  C CD1 . ILE B 1 289 ? 189.641 187.125 165.298 1.00 53.95  ? 310 ILE B CD1 1 
ATOM   5691  N N   . ILE B 1 290 ? 193.212 186.538 168.485 1.00 61.27  ? 311 ILE B N   1 
ATOM   5692  C CA  . ILE B 1 290 ? 194.578 186.432 168.984 1.00 61.27  ? 311 ILE B CA  1 
ATOM   5693  C C   . ILE B 1 290 ? 195.547 186.727 167.843 1.00 61.27  ? 311 ILE B C   1 
ATOM   5694  O O   . ILE B 1 290 ? 195.466 186.121 166.767 1.00 61.27  ? 311 ILE B O   1 
ATOM   5695  C CB  . ILE B 1 290 ? 194.832 185.048 169.614 1.00 61.27  ? 311 ILE B CB  1 
ATOM   5696  C CG1 . ILE B 1 290 ? 196.325 184.827 169.877 1.00 61.27  ? 311 ILE B CG1 1 
ATOM   5697  C CG2 . ILE B 1 290 ? 194.196 183.923 168.798 1.00 61.27  ? 311 ILE B CG2 1 
ATOM   5698  C CD1 . ILE B 1 290 ? 196.619 183.613 170.730 1.00 61.27  ? 311 ILE B CD1 1 
ATOM   5699  N N   . ILE B 1 291 ? 196.444 187.687 168.062 1.00 62.19  ? 312 ILE B N   1 
ATOM   5700  C CA  . ILE B 1 291 ? 197.400 188.128 167.054 1.00 62.19  ? 312 ILE B CA  1 
ATOM   5701  C C   . ILE B 1 291 ? 198.801 187.859 167.580 1.00 62.19  ? 312 ILE B C   1 
ATOM   5702  O O   . ILE B 1 291 ? 199.143 188.283 168.690 1.00 62.19  ? 312 ILE B O   1 
ATOM   5703  C CB  . ILE B 1 291 ? 197.217 189.620 166.715 1.00 62.19  ? 312 ILE B CB  1 
ATOM   5704  C CG1 . ILE B 1 291 ? 195.799 189.883 166.207 1.00 62.19  ? 312 ILE B CG1 1 
ATOM   5705  C CG2 . ILE B 1 291 ? 198.239 190.070 165.684 1.00 62.19  ? 312 ILE B CG2 1 
ATOM   5706  C CD1 . ILE B 1 291 ? 195.482 191.347 166.012 1.00 62.19  ? 312 ILE B CD1 1 
ATOM   5707  N N   . ARG B 1 292 ? 199.608 187.153 166.787 1.00 82.22  ? 313 ARG B N   1 
ATOM   5708  C CA  . ARG B 1 292 ? 200.970 186.814 167.196 1.00 82.22  ? 313 ARG B CA  1 
ATOM   5709  C C   . ARG B 1 292 ? 201.834 186.755 165.938 1.00 82.22  ? 313 ARG B C   1 
ATOM   5710  O O   . ARG B 1 292 ? 201.833 185.741 165.232 1.00 82.22  ? 313 ARG B O   1 
ATOM   5711  C CB  . ARG B 1 292 ? 201.000 185.498 167.961 1.00 82.22  ? 313 ARG B CB  1 
ATOM   5712  C CG  . ARG B 1 292 ? 202.388 185.064 168.418 1.00 82.22  ? 313 ARG B CG  1 
ATOM   5713  C CD  . ARG B 1 292 ? 202.375 183.746 169.193 1.00 82.22  ? 313 ARG B CD  1 
ATOM   5714  N NE  . ARG B 1 292 ? 201.803 182.637 168.435 1.00 82.22  ? 313 ARG B NE  1 
ATOM   5715  C CZ  . ARG B 1 292 ? 200.617 182.093 168.675 1.00 82.22  ? 313 ARG B CZ  1 
ATOM   5716  N NH1 . ARG B 1 292 ? 199.841 182.531 169.652 1.00 82.22  ? 313 ARG B NH1 1 
ATOM   5717  N NH2 . ARG B 1 292 ? 200.200 181.085 167.914 1.00 82.22  ? 313 ARG B NH2 1 
ATOM   5718  N N   . GLY B 1 293 ? 202.568 187.836 165.675 1.00 96.79  ? 314 GLY B N   1 
ATOM   5719  C CA  . GLY B 1 293 ? 203.473 187.905 164.542 1.00 96.79  ? 314 GLY B CA  1 
ATOM   5720  C C   . GLY B 1 293 ? 202.799 187.843 163.186 1.00 96.79  ? 314 GLY B C   1 
ATOM   5721  O O   . GLY B 1 293 ? 203.238 187.083 162.315 1.00 96.79  ? 314 GLY B O   1 
ATOM   5722  N N   . TYR B 1 294 ? 201.729 188.637 163.022 1.00 97.50  ? 315 TYR B N   1 
ATOM   5723  C CA  . TYR B 1 294 ? 200.881 188.673 161.819 1.00 97.50  ? 315 TYR B CA  1 
ATOM   5724  C C   . TYR B 1 294 ? 200.305 187.296 161.490 1.00 97.50  ? 315 TYR B C   1 
ATOM   5725  O O   . TYR B 1 294 ? 200.202 186.905 160.326 1.00 97.50  ? 315 TYR B O   1 
ATOM   5726  C CB  . TYR B 1 294 ? 201.620 189.260 160.610 1.00 97.50  ? 315 TYR B CB  1 
ATOM   5727  C CG  . TYR B 1 294 ? 201.808 190.763 160.644 1.00 97.50  ? 315 TYR B CG  1 
ATOM   5728  C CD1 . TYR B 1 294 ? 201.187 191.547 161.612 1.00 97.50  ? 315 TYR B CD1 1 
ATOM   5729  C CD2 . TYR B 1 294 ? 202.611 191.397 159.701 1.00 97.50  ? 315 TYR B CD2 1 
ATOM   5730  C CE1 . TYR B 1 294 ? 201.361 192.921 161.640 1.00 97.50  ? 315 TYR B CE1 1 
ATOM   5731  C CE2 . TYR B 1 294 ? 202.791 192.769 159.721 1.00 97.50  ? 315 TYR B CE2 1 
ATOM   5732  C CZ  . TYR B 1 294 ? 202.164 193.524 160.692 1.00 97.50  ? 315 TYR B CZ  1 
ATOM   5733  O OH  . TYR B 1 294 ? 202.342 194.888 160.714 1.00 97.50  ? 315 TYR B OH  1 
ATOM   5734  N N   . HIS B 1 295 ? 199.930 186.555 162.530 1.00 91.42  ? 316 HIS B N   1 
ATOM   5735  C CA  . HIS B 1 295 ? 199.282 185.255 162.393 1.00 91.42  ? 316 HIS B CA  1 
ATOM   5736  C C   . HIS B 1 295 ? 198.015 185.286 163.233 1.00 91.42  ? 316 HIS B C   1 
ATOM   5737  O O   . HIS B 1 295 ? 198.079 185.476 164.452 1.00 91.42  ? 316 HIS B O   1 
ATOM   5738  C CB  . HIS B 1 295 ? 200.206 184.120 162.833 1.00 91.42  ? 316 HIS B CB  1 
ATOM   5739  C CG  . HIS B 1 295 ? 199.848 182.790 162.249 1.00 91.42  ? 316 HIS B CG  1 
ATOM   5740  N ND1 . HIS B 1 295 ? 200.638 181.672 162.406 1.00 91.42  ? 316 HIS B ND1 1 
ATOM   5741  C CD2 . HIS B 1 295 ? 198.785 182.399 161.508 1.00 91.42  ? 316 HIS B CD2 1 
ATOM   5742  C CE1 . HIS B 1 295 ? 200.077 180.649 161.786 1.00 91.42  ? 316 HIS B CE1 1 
ATOM   5743  N NE2 . HIS B 1 295 ? 198.951 181.063 161.234 1.00 91.42  ? 316 HIS B NE2 1 
ATOM   5744  N N   . LEU B 1 296 ? 196.871 185.100 162.587 1.00 80.68  ? 317 LEU B N   1 
ATOM   5745  C CA  . LEU B 1 296 ? 195.580 185.255 163.236 1.00 80.68  ? 317 LEU B CA  1 
ATOM   5746  C C   . LEU B 1 296 ? 194.950 183.894 163.498 1.00 80.68  ? 317 LEU B C   1 
ATOM   5747  O O   . LEU B 1 296 ? 195.030 182.989 162.662 1.00 80.68  ? 317 LEU B O   1 
ATOM   5748  C CB  . LEU B 1 296 ? 194.648 186.108 162.377 1.00 80.68  ? 317 LEU B CB  1 
ATOM   5749  C CG  . LEU B 1 296 ? 195.245 187.361 161.734 1.00 80.68  ? 317 LEU B CG  1 
ATOM   5750  C CD1 . LEU B 1 296 ? 194.225 188.027 160.825 1.00 80.68  ? 317 LEU B CD1 1 
ATOM   5751  C CD2 . LEU B 1 296 ? 195.730 188.332 162.794 1.00 80.68  ? 317 LEU B CD2 1 
ATOM   5752  N N   . SER B 1 297 ? 194.328 183.755 164.666 1.00 77.48  ? 318 SER B N   1 
ATOM   5753  C CA  . SER B 1 297 ? 193.673 182.516 165.058 1.00 77.48  ? 318 SER B CA  1 
ATOM   5754  C C   . SER B 1 297 ? 192.435 182.859 165.877 1.00 77.48  ? 318 SER B C   1 
ATOM   5755  O O   . SER B 1 297 ? 192.050 184.025 165.999 1.00 77.48  ? 318 SER B O   1 
ATOM   5756  C CB  . SER B 1 297 ? 194.631 181.609 165.837 1.00 77.48  ? 318 SER B CB  1 
ATOM   5757  O OG  . SER B 1 297 ? 195.744 181.238 165.043 1.00 77.48  ? 318 SER B OG  1 
ATOM   5758  N N   . LEU B 1 298 ? 191.808 181.828 166.439 1.00 75.48  ? 319 LEU B N   1 
ATOM   5759  C CA  . LEU B 1 298 ? 190.633 181.981 167.287 1.00 75.48  ? 319 LEU B CA  1 
ATOM   5760  C C   . LEU B 1 298 ? 190.864 181.302 168.628 1.00 75.48  ? 319 LEU B C   1 
ATOM   5761  O O   . LEU B 1 298 ? 191.519 180.257 168.703 1.00 75.48  ? 319 LEU B O   1 
ATOM   5762  C CB  . LEU B 1 298 ? 189.383 181.391 166.627 1.00 75.48  ? 319 LEU B CB  1 
ATOM   5763  C CG  . LEU B 1 298 ? 188.862 182.081 165.368 1.00 75.48  ? 319 LEU B CG  1 
ATOM   5764  C CD1 . LEU B 1 298 ? 187.712 181.292 164.768 1.00 75.48  ? 319 LEU B CD1 1 
ATOM   5765  C CD2 . LEU B 1 298 ? 188.426 183.501 165.684 1.00 75.48  ? 319 LEU B CD2 1 
ATOM   5766  N N   . ILE B 1 299 ? 190.321 181.904 169.687 1.00 64.75  ? 320 ILE B N   1 
ATOM   5767  C CA  . ILE B 1 299 ? 190.342 181.327 171.023 1.00 64.75  ? 320 ILE B CA  1 
ATOM   5768  C C   . ILE B 1 299 ? 188.925 181.358 171.575 1.00 64.75  ? 320 ILE B C   1 
ATOM   5769  O O   . ILE B 1 299 ? 188.078 182.138 171.134 1.00 64.75  ? 320 ILE B O   1 
ATOM   5770  C CB  . ILE B 1 299 ? 191.301 182.069 171.978 1.00 64.75  ? 320 ILE B CB  1 
ATOM   5771  C CG1 . ILE B 1 299 ? 191.009 183.568 171.967 1.00 64.75  ? 320 ILE B CG1 1 
ATOM   5772  C CG2 . ILE B 1 299 ? 192.752 181.798 171.607 1.00 64.75  ? 320 ILE B CG2 1 
ATOM   5773  C CD1 . ILE B 1 299 ? 191.710 184.326 173.066 1.00 64.75  ? 320 ILE B CD1 1 
ATOM   5774  N N   . ASP B 1 300 ? 188.672 180.492 172.551 1.00 58.06  ? 321 ASP B N   1 
ATOM   5775  C CA  . ASP B 1 300 ? 187.387 180.437 173.234 1.00 58.06  ? 321 ASP B CA  1 
ATOM   5776  C C   . ASP B 1 300 ? 187.597 180.676 174.722 1.00 58.06  ? 321 ASP B C   1 
ATOM   5777  O O   . ASP B 1 300 ? 188.413 180.000 175.358 1.00 58.06  ? 321 ASP B O   1 
ATOM   5778  C CB  . ASP B 1 300 ? 186.684 179.096 172.987 1.00 58.06  ? 321 ASP B CB  1 
ATOM   5779  C CG  . ASP B 1 300 ? 187.588 177.905 173.229 1.00 58.06  ? 321 ASP B CG  1 
ATOM   5780  O OD1 . ASP B 1 300 ? 188.811 178.031 173.010 1.00 58.06  ? 321 ASP B OD1 1 
ATOM   5781  O OD2 . ASP B 1 300 ? 187.075 176.842 173.636 1.00 58.06  ? 321 ASP B OD2 1 
ATOM   5782  N N   . SER B 1 301 ? 186.878 181.650 175.268 1.00 55.15  ? 322 SER B N   1 
ATOM   5783  C CA  . SER B 1 301 ? 186.966 181.976 176.691 1.00 55.15  ? 322 SER B CA  1 
ATOM   5784  C C   . SER B 1 301 ? 185.850 181.283 177.469 1.00 55.15  ? 322 SER B C   1 
ATOM   5785  O O   . SER B 1 301 ? 185.050 181.908 178.165 1.00 55.15  ? 322 SER B O   1 
ATOM   5786  C CB  . SER B 1 301 ? 186.926 183.488 176.889 1.00 55.15  ? 322 SER B CB  1 
ATOM   5787  O OG  . SER B 1 301 ? 185.635 184.005 176.616 1.00 55.15  ? 322 SER B OG  1 
ATOM   5788  N N   . THR B 1 302 ? 185.806 179.958 177.340 1.00 55.29  ? 323 THR B N   1 
ATOM   5789  C CA  . THR B 1 302 ? 184.835 179.156 178.069 1.00 55.29  ? 323 THR B CA  1 
ATOM   5790  C C   . THR B 1 302 ? 185.357 178.674 179.413 1.00 55.29  ? 323 THR B C   1 
ATOM   5791  O O   . THR B 1 302 ? 184.559 178.265 180.263 1.00 55.29  ? 323 THR B O   1 
ATOM   5792  C CB  . THR B 1 302 ? 184.410 177.945 177.233 1.00 55.29  ? 323 THR B CB  1 
ATOM   5793  O OG1 . THR B 1 302 ? 185.483 176.997 177.185 1.00 55.29  ? 323 THR B OG1 1 
ATOM   5794  C CG2 . THR B 1 302 ? 184.058 178.376 175.819 1.00 55.29  ? 323 THR B CG2 1 
ATOM   5795  N N   . ASN B 1 303 ? 186.674 178.716 179.623 1.00 56.03  ? 324 ASN B N   1 
ATOM   5796  C CA  . ASN B 1 303 ? 187.280 178.294 180.878 1.00 56.03  ? 324 ASN B CA  1 
ATOM   5797  C C   . ASN B 1 303 ? 188.327 179.285 181.372 1.00 56.03  ? 324 ASN B C   1 
ATOM   5798  O O   . ASN B 1 303 ? 188.982 179.020 182.386 1.00 56.03  ? 324 ASN B O   1 
ATOM   5799  C CB  . ASN B 1 303 ? 187.911 176.906 180.729 1.00 56.03  ? 324 ASN B CB  1 
ATOM   5800  C CG  . ASN B 1 303 ? 186.878 175.810 180.570 1.00 56.03  ? 324 ASN B CG  1 
ATOM   5801  O OD1 . ASN B 1 303 ? 185.853 175.803 181.251 1.00 56.03  ? 324 ASN B OD1 1 
ATOM   5802  N ND2 . ASN B 1 303 ? 187.141 174.877 179.661 1.00 56.03  ? 324 ASN B ND2 1 
ATOM   5803  N N   . CYS B 1 304 ? 188.497 180.412 180.690 1.00 45.16  ? 325 CYS B N   1 
ATOM   5804  C CA  . CYS B 1 304 ? 189.528 181.387 181.011 1.00 45.16  ? 325 CYS B CA  1 
ATOM   5805  C C   . CYS B 1 304 ? 188.894 182.600 181.676 1.00 45.16  ? 325 CYS B C   1 
ATOM   5806  O O   . CYS B 1 304 ? 187.902 183.138 181.175 1.00 45.16  ? 325 CYS B O   1 
ATOM   5807  C CB  . CYS B 1 304 ? 190.284 181.816 179.752 1.00 45.16  ? 325 CYS B CB  1 
ATOM   5808  S SG  . CYS B 1 304 ? 191.023 180.459 178.821 1.00 45.16  ? 325 CYS B SG  1 
ATOM   5809  N N   . ILE B 1 305 ? 189.464 183.024 182.797 1.00 36.44  ? 326 ILE B N   1 
ATOM   5810  C CA  . ILE B 1 305 ? 189.009 184.238 183.462 1.00 36.44  ? 326 ILE B CA  1 
ATOM   5811  C C   . ILE B 1 305 ? 189.629 185.446 182.774 1.00 36.44  ? 326 ILE B C   1 
ATOM   5812  O O   . ILE B 1 305 ? 190.760 185.392 182.273 1.00 36.44  ? 326 ILE B O   1 
ATOM   5813  C CB  . ILE B 1 305 ? 189.329 184.190 184.970 1.00 36.44  ? 326 ILE B CB  1 
ATOM   5814  C CG1 . ILE B 1 305 ? 190.832 184.083 185.235 1.00 36.44  ? 326 ILE B CG1 1 
ATOM   5815  C CG2 . ILE B 1 305 ? 188.594 183.039 185.635 1.00 36.44  ? 326 ILE B CG2 1 
ATOM   5816  C CD1 . ILE B 1 305 ? 191.203 184.261 186.693 1.00 36.44  ? 326 ILE B CD1 1 
ATOM   5817  N N   . ILE B 1 306 ? 188.862 186.527 182.690 1.00 36.87  ? 327 ILE B N   1 
ATOM   5818  C CA  . ILE B 1 306 ? 189.284 187.743 182.007 1.00 36.87  ? 327 ILE B CA  1 
ATOM   5819  C C   . ILE B 1 306 ? 189.592 188.800 183.056 1.00 36.87  ? 327 ILE B C   1 
ATOM   5820  O O   . ILE B 1 306 ? 188.701 189.225 183.801 1.00 36.87  ? 327 ILE B O   1 
ATOM   5821  C CB  . ILE B 1 306 ? 188.210 188.234 181.024 1.00 36.87  ? 327 ILE B CB  1 
ATOM   5822  C CG1 . ILE B 1 306 ? 187.909 187.152 179.985 1.00 36.87  ? 327 ILE B CG1 1 
ATOM   5823  C CG2 . ILE B 1 306 ? 188.654 189.520 180.348 1.00 36.87  ? 327 ILE B CG2 1 
ATOM   5824  C CD1 . ILE B 1 306 ? 186.700 187.444 179.126 1.00 36.87  ? 327 ILE B CD1 1 
ATOM   5825  N N   . THR B 1 307 ? 190.849 189.225 183.117 1.00 36.73  ? 328 THR B N   1 
ATOM   5826  C CA  . THR B 1 307 ? 191.260 190.263 184.048 1.00 36.73  ? 328 THR B CA  1 
ATOM   5827  C C   . THR B 1 307 ? 191.133 191.628 183.373 1.00 36.73  ? 328 THR B C   1 
ATOM   5828  O O   . THR B 1 307 ? 190.612 191.752 182.262 1.00 36.73  ? 328 THR B O   1 
ATOM   5829  C CB  . THR B 1 307 ? 192.680 190.006 184.545 1.00 36.73  ? 328 THR B CB  1 
ATOM   5830  O OG1 . THR B 1 307 ? 193.620 190.389 183.534 1.00 36.73  ? 328 THR B OG1 1 
ATOM   5831  C CG2 . THR B 1 307 ? 192.868 188.534 184.881 1.00 36.73  ? 328 THR B CG2 1 
ATOM   5832  N N   . ASP B 1 308 ? 191.609 192.674 184.049 1.00 40.35  ? 329 ASP B N   1 
ATOM   5833  C CA  . ASP B 1 308 ? 191.509 194.022 183.503 1.00 40.35  ? 329 ASP B CA  1 
ATOM   5834  C C   . ASP B 1 308 ? 192.518 194.275 182.391 1.00 40.35  ? 329 ASP B C   1 
ATOM   5835  O O   . ASP B 1 308 ? 192.290 195.143 181.542 1.00 40.35  ? 329 ASP B O   1 
ATOM   5836  C CB  . ASP B 1 308 ? 191.692 195.053 184.617 1.00 40.35  ? 329 ASP B CB  1 
ATOM   5837  C CG  . ASP B 1 308 ? 192.914 194.777 185.472 1.00 40.35  ? 329 ASP B CG  1 
ATOM   5838  O OD1 . ASP B 1 308 ? 193.522 193.697 185.319 1.00 40.35  ? 329 ASP B OD1 1 
ATOM   5839  O OD2 . ASP B 1 308 ? 193.267 195.644 186.298 1.00 40.35  ? 329 ASP B OD2 1 
ATOM   5840  N N   . ASN B 1 309 ? 193.632 193.539 182.376 1.00 38.60  ? 330 ASN B N   1 
ATOM   5841  C CA  . ASN B 1 309 ? 194.704 193.791 181.426 1.00 38.60  ? 330 ASN B CA  1 
ATOM   5842  C C   . ASN B 1 309 ? 195.106 192.592 180.580 1.00 38.60  ? 330 ASN B C   1 
ATOM   5843  O O   . ASN B 1 309 ? 195.731 192.789 179.533 1.00 38.60  ? 330 ASN B O   1 
ATOM   5844  C CB  . ASN B 1 309 ? 195.951 194.317 182.157 1.00 38.60  ? 330 ASN B CB  1 
ATOM   5845  C CG  . ASN B 1 309 ? 196.352 193.449 183.340 1.00 38.60  ? 330 ASN B CG  1 
ATOM   5846  O OD1 . ASN B 1 309 ? 195.742 192.413 183.608 1.00 38.60  ? 330 ASN B OD1 1 
ATOM   5847  N ND2 . ASN B 1 309 ? 197.385 193.874 184.056 1.00 38.60  ? 330 ASN B ND2 1 
ATOM   5848  N N   . SER B 1 310 ? 194.778 191.368 180.989 1.00 35.29  ? 331 SER B N   1 
ATOM   5849  C CA  . SER B 1 310 ? 195.258 190.198 180.272 1.00 35.29  ? 331 SER B CA  1 
ATOM   5850  C C   . SER B 1 310 ? 194.276 189.047 180.423 1.00 35.29  ? 331 SER B C   1 
ATOM   5851  O O   . SER B 1 310 ? 193.453 189.018 181.342 1.00 35.29  ? 331 SER B O   1 
ATOM   5852  C CB  . SER B 1 310 ? 196.643 189.769 180.768 1.00 35.29  ? 331 SER B CB  1 
ATOM   5853  O OG  . SER B 1 310 ? 197.035 188.547 180.171 1.00 35.29  ? 331 SER B OG  1 
ATOM   5854  N N   . TYR B 1 311 ? 194.379 188.095 179.500 1.00 36.55  ? 332 TYR B N   1 
ATOM   5855  C CA  . TYR B 1 311 ? 193.625 186.853 179.568 1.00 36.55  ? 332 TYR B CA  1 
ATOM   5856  C C   . TYR B 1 311 ? 194.464 185.796 180.269 1.00 36.55  ? 332 TYR B C   1 
ATOM   5857  O O   . TYR B 1 311 ? 195.615 185.557 179.889 1.00 36.55  ? 332 TYR B O   1 
ATOM   5858  C CB  . TYR B 1 311 ? 193.247 186.369 178.168 1.00 36.55  ? 332 TYR B CB  1 
ATOM   5859  C CG  . TYR B 1 311 ? 191.924 186.889 177.663 1.00 36.55  ? 332 TYR B CG  1 
ATOM   5860  C CD1 . TYR B 1 311 ? 191.703 188.251 177.516 1.00 36.55  ? 332 TYR B CD1 1 
ATOM   5861  C CD2 . TYR B 1 311 ? 190.899 186.014 177.324 1.00 36.55  ? 332 TYR B CD2 1 
ATOM   5862  C CE1 . TYR B 1 311 ? 190.493 188.731 177.051 1.00 36.55  ? 332 TYR B CE1 1 
ATOM   5863  C CE2 . TYR B 1 311 ? 189.685 186.484 176.857 1.00 36.55  ? 332 TYR B CE2 1 
ATOM   5864  C CZ  . TYR B 1 311 ? 189.489 187.843 176.724 1.00 36.55  ? 332 TYR B CZ  1 
ATOM   5865  O OH  . TYR B 1 311 ? 188.285 188.320 176.261 1.00 36.55  ? 332 TYR B OH  1 
ATOM   5866  N N   . VAL B 1 312 ? 193.890 185.162 181.285 1.00 37.20  ? 333 VAL B N   1 
ATOM   5867  C CA  . VAL B 1 312 ? 194.552 184.083 182.008 1.00 37.20  ? 333 VAL B CA  1 
ATOM   5868  C C   . VAL B 1 312 ? 193.796 182.798 181.716 1.00 37.20  ? 333 VAL B C   1 
ATOM   5869  O O   . VAL B 1 312 ? 192.605 182.686 182.032 1.00 37.20  ? 333 VAL B O   1 
ATOM   5870  C CB  . VAL B 1 312 ? 194.615 184.352 183.517 1.00 37.20  ? 333 VAL B CB  1 
ATOM   5871  C CG1 . VAL B 1 312 ? 195.254 183.176 184.228 1.00 37.20  ? 333 VAL B CG1 1 
ATOM   5872  C CG2 . VAL B 1 312 ? 195.397 185.622 183.787 1.00 37.20  ? 333 VAL B CG2 1 
ATOM   5873  N N   . CYS B 1 313 ? 194.487 181.833 181.121 1.00 47.63  ? 334 CYS B N   1 
ATOM   5874  C CA  . CYS B 1 313 ? 193.898 180.559 180.751 1.00 47.63  ? 334 CYS B CA  1 
ATOM   5875  C C   . CYS B 1 313 ? 194.579 179.433 181.514 1.00 47.63  ? 334 CYS B C   1 
ATOM   5876  O O   . CYS B 1 313 ? 195.726 179.560 181.952 1.00 47.63  ? 334 CYS B O   1 
ATOM   5877  C CB  . CYS B 1 313 ? 194.015 180.301 179.243 1.00 47.63  ? 334 CYS B CB  1 
ATOM   5878  S SG  . CYS B 1 313 ? 192.821 181.197 178.233 1.00 47.63  ? 334 CYS B SG  1 
ATOM   5879  N N   . ASP B 1 314 ? 193.838 178.340 181.691 1.00 60.73  ? 335 ASP B N   1 
ATOM   5880  C CA  . ASP B 1 314 ? 194.422 177.121 182.239 1.00 60.73  ? 335 ASP B CA  1 
ATOM   5881  C C   . ASP B 1 314 ? 195.456 176.530 181.290 1.00 60.73  ? 335 ASP B C   1 
ATOM   5882  O O   . ASP B 1 314 ? 196.507 176.047 181.726 1.00 60.73  ? 335 ASP B O   1 
ATOM   5883  C CB  . ASP B 1 314 ? 193.317 176.103 182.516 1.00 60.73  ? 335 ASP B CB  1 
ATOM   5884  C CG  . ASP B 1 314 ? 193.763 174.992 183.441 1.00 60.73  ? 335 ASP B CG  1 
ATOM   5885  O OD1 . ASP B 1 314 ? 194.886 175.071 183.982 1.00 60.73  ? 335 ASP B OD1 1 
ATOM   5886  O OD2 . ASP B 1 314 ? 192.992 174.026 183.614 1.00 60.73  ? 335 ASP B OD2 1 
ATOM   5887  N N   . ARG B 1 315 ? 195.173 176.574 179.991 1.00 75.31  ? 336 ARG B N   1 
ATOM   5888  C CA  . ARG B 1 315 ? 195.901 175.820 178.982 1.00 75.31  ? 336 ARG B CA  1 
ATOM   5889  C C   . ARG B 1 315 ? 195.582 176.475 177.642 1.00 75.31  ? 336 ARG B C   1 
ATOM   5890  O O   . ARG B 1 315 ? 194.599 177.212 177.523 1.00 75.31  ? 336 ARG B O   1 
ATOM   5891  C CB  . ARG B 1 315 ? 195.506 174.333 179.090 1.00 75.31  ? 336 ARG B CB  1 
ATOM   5892  C CG  . ARG B 1 315 ? 196.206 173.274 178.244 1.00 75.31  ? 336 ARG B CG  1 
ATOM   5893  C CD  . ARG B 1 315 ? 195.518 173.045 176.918 1.00 75.31  ? 336 ARG B CD  1 
ATOM   5894  N NE  . ARG B 1 315 ? 194.110 172.726 177.124 1.00 75.31  ? 336 ARG B NE  1 
ATOM   5895  C CZ  . ARG B 1 315 ? 193.637 171.529 177.450 1.00 75.31  ? 336 ARG B CZ  1 
ATOM   5896  N NH1 . ARG B 1 315 ? 194.440 170.495 177.658 1.00 75.31  ? 336 ARG B NH1 1 
ATOM   5897  N NH2 . ARG B 1 315 ? 192.322 171.362 177.569 1.00 75.31  ? 336 ARG B NH2 1 
ATOM   5898  N N   . ASP B 1 316 ? 196.453 176.248 176.656 1.00 66.67  ? 337 ASP B N   1 
ATOM   5899  C CA  . ASP B 1 316 ? 196.328 176.903 175.356 1.00 66.67  ? 337 ASP B CA  1 
ATOM   5900  C C   . ASP B 1 316 ? 195.078 176.439 174.613 1.00 66.67  ? 337 ASP B C   1 
ATOM   5901  O O   . ASP B 1 316 ? 194.784 175.243 174.542 1.00 66.67  ? 337 ASP B O   1 
ATOM   5902  C CB  . ASP B 1 316 ? 197.564 176.629 174.500 1.00 66.67  ? 337 ASP B CB  1 
ATOM   5903  C CG  . ASP B 1 316 ? 197.792 177.695 173.439 1.00 66.67  ? 337 ASP B CG  1 
ATOM   5904  O OD1 . ASP B 1 316 ? 196.984 178.645 173.356 1.00 66.67  ? 337 ASP B OD1 1 
ATOM   5905  O OD2 . ASP B 1 316 ? 198.778 177.576 172.683 1.00 66.67  ? 337 ASP B OD2 1 
ATOM   5906  N N   . TYR B 1 317 ? 194.357 177.401 174.039 1.00 64.49  ? 338 TYR B N   1 
ATOM   5907  C CA  . TYR B 1 317 ? 193.075 177.169 173.381 1.00 64.49  ? 338 TYR B CA  1 
ATOM   5908  C C   . TYR B 1 317 ? 193.056 177.819 172.004 1.00 64.49  ? 338 TYR B C   1 
ATOM   5909  O O   . TYR B 1 317 ? 192.105 178.507 171.627 1.00 64.49  ? 338 TYR B O   1 
ATOM   5910  C CB  . TYR B 1 317 ? 191.924 177.701 174.233 1.00 64.49  ? 338 TYR B CB  1 
ATOM   5911  C CG  . TYR B 1 317 ? 191.589 176.861 175.446 1.00 64.49  ? 338 TYR B CG  1 
ATOM   5912  C CD1 . TYR B 1 317 ? 191.629 175.474 175.387 1.00 64.49  ? 338 TYR B CD1 1 
ATOM   5913  C CD2 . TYR B 1 317 ? 191.218 177.458 176.647 1.00 64.49  ? 338 TYR B CD2 1 
ATOM   5914  C CE1 . TYR B 1 317 ? 191.318 174.701 176.495 1.00 64.49  ? 338 TYR B CE1 1 
ATOM   5915  C CE2 . TYR B 1 317 ? 190.904 176.694 177.760 1.00 64.49  ? 338 TYR B CE2 1 
ATOM   5916  C CZ  . TYR B 1 317 ? 190.956 175.317 177.676 1.00 64.49  ? 338 TYR B CZ  1 
ATOM   5917  O OH  . TYR B 1 317 ? 190.646 174.551 178.777 1.00 64.49  ? 338 TYR B OH  1 
ATOM   5918  N N   . SER B 1 318 ? 194.112 177.607 171.224 1.00 73.14  ? 339 SER B N   1 
ATOM   5919  C CA  . SER B 1 318 ? 194.223 178.210 169.902 1.00 73.14  ? 339 SER B CA  1 
ATOM   5920  C C   . SER B 1 318 ? 193.533 177.320 168.873 1.00 73.14  ? 339 SER B C   1 
ATOM   5921  O O   . SER B 1 318 ? 193.855 176.133 168.751 1.00 73.14  ? 339 SER B O   1 
ATOM   5922  C CB  . SER B 1 318 ? 195.688 178.432 169.527 1.00 73.14  ? 339 SER B CB  1 
ATOM   5923  O OG  . SER B 1 318 ? 195.799 179.036 168.250 1.00 73.14  ? 339 SER B OG  1 
ATOM   5924  N N   . LEU B 1 319 ? 192.579 177.896 168.139 1.00 76.02  ? 340 LEU B N   1 
ATOM   5925  C CA  . LEU B 1 319 ? 191.831 177.235 167.083 1.00 76.02  ? 340 LEU B CA  1 
ATOM   5926  C C   . LEU B 1 319 ? 192.187 177.839 165.726 1.00 76.02  ? 340 LEU B C   1 
ATOM   5927  O O   . LEU B 1 319 ? 192.526 179.024 165.648 1.00 76.02  ? 340 LEU B O   1 
ATOM   5928  C CB  . LEU B 1 319 ? 190.320 177.364 167.321 1.00 76.02  ? 340 LEU B CB  1 
ATOM   5929  C CG  . LEU B 1 319 ? 189.769 176.703 168.585 1.00 76.02  ? 340 LEU B CG  1 
ATOM   5930  C CD1 . LEU B 1 319 ? 189.455 177.741 169.651 1.00 76.02  ? 340 LEU B CD1 1 
ATOM   5931  C CD2 . LEU B 1 319 ? 188.538 175.875 168.256 1.00 76.02  ? 340 LEU B CD2 1 
ATOM   5932  N N   . PRO B 1 320 ? 192.145 177.056 164.644 1.00 82.21  ? 341 PRO B N   1 
ATOM   5933  C CA  . PRO B 1 320 ? 192.434 177.620 163.320 1.00 82.21  ? 341 PRO B CA  1 
ATOM   5934  C C   . PRO B 1 320 ? 191.333 178.557 162.852 1.00 82.21  ? 341 PRO B C   1 
ATOM   5935  O O   . PRO B 1 320 ? 190.175 178.452 163.263 1.00 82.21  ? 341 PRO B O   1 
ATOM   5936  C CB  . PRO B 1 320 ? 192.532 176.383 162.421 1.00 82.21  ? 341 PRO B CB  1 
ATOM   5937  C CG  . PRO B 1 320 ? 191.685 175.373 163.100 1.00 82.21  ? 341 PRO B CG  1 
ATOM   5938  C CD  . PRO B 1 320 ? 191.904 175.603 164.568 1.00 82.21  ? 341 PRO B CD  1 
ATOM   5939  N N   . MET B 1 321 ? 191.711 179.483 161.977 1.00 90.81  ? 342 MET B N   1 
ATOM   5940  C CA  . MET B 1 321 ? 190.835 180.572 161.578 1.00 90.81  ? 342 MET B CA  1 
ATOM   5941  C C   . MET B 1 321 ? 190.729 180.586 160.056 1.00 90.81  ? 342 MET B C   1 
ATOM   5942  O O   . MET B 1 321 ? 191.650 180.165 159.350 1.00 90.81  ? 342 MET B O   1 
ATOM   5943  C CB  . MET B 1 321 ? 191.363 181.911 162.137 1.00 90.81  ? 342 MET B CB  1 
ATOM   5944  C CG  . MET B 1 321 ? 190.392 183.090 162.099 1.00 90.81  ? 342 MET B CG  1 
ATOM   5945  S SD  . MET B 1 321 ? 190.341 184.015 160.561 1.00 90.81  ? 342 MET B SD  1 
ATOM   5946  C CE  . MET B 1 321 ? 191.291 185.469 160.975 1.00 90.81  ? 342 MET B CE  1 
ATOM   5947  N N   . ASN B 1 322 ? 189.584 181.058 159.567 1.00 99.03  ? 343 ASN B N   1 
ATOM   5948  C CA  . ASN B 1 322 ? 189.197 180.869 158.174 1.00 99.03  ? 343 ASN B CA  1 
ATOM   5949  C C   . ASN B 1 322 ? 190.026 181.746 157.235 1.00 99.03  ? 343 ASN B C   1 
ATOM   5950  O O   . ASN B 1 322 ? 190.317 182.899 157.561 1.00 99.03  ? 343 ASN B O   1 
ATOM   5951  C CB  . ASN B 1 322 ? 187.721 181.210 158.004 1.00 99.03  ? 343 ASN B CB  1 
ATOM   5952  C CG  . ASN B 1 322 ? 187.076 180.460 156.875 1.00 99.03  ? 343 ASN B CG  1 
ATOM   5953  O OD1 . ASN B 1 322 ? 187.435 180.624 155.713 1.00 99.03  ? 343 ASN B OD1 1 
ATOM   5954  N ND2 . ASN B 1 322 ? 186.086 179.652 157.208 1.00 99.03  ? 343 ASN B ND2 1 
ATOM   5955  N N   . PRO B 1 323 ? 190.428 181.225 156.069 1.00 100.87 ? 344 PRO B N   1 
ATOM   5956  C CA  . PRO B 1 323 ? 190.981 182.112 155.026 1.00 100.87 ? 344 PRO B CA  1 
ATOM   5957  C C   . PRO B 1 323 ? 189.992 183.152 154.519 1.00 100.87 ? 344 PRO B C   1 
ATOM   5958  O O   . PRO B 1 323 ? 190.398 184.274 154.186 1.00 100.87 ? 344 PRO B O   1 
ATOM   5959  C CB  . PRO B 1 323 ? 191.391 181.129 153.921 1.00 100.87 ? 344 PRO B CB  1 
ATOM   5960  C CG  . PRO B 1 323 ? 191.645 179.848 154.639 1.00 100.87 ? 344 PRO B CG  1 
ATOM   5961  C CD  . PRO B 1 323 ? 190.637 179.802 155.751 1.00 100.87 ? 344 PRO B CD  1 
ATOM   5962  N N   . ILE B 1 324 ? 188.702 182.805 154.447 1.00 96.14  ? 345 ILE B N   1 
ATOM   5963  C CA  . ILE B 1 324 ? 187.682 183.781 154.070 1.00 96.14  ? 345 ILE B CA  1 
ATOM   5964  C C   . ILE B 1 324 ? 187.540 184.846 155.149 1.00 96.14  ? 345 ILE B C   1 
ATOM   5965  O O   . ILE B 1 324 ? 187.452 186.043 154.852 1.00 96.14  ? 345 ILE B O   1 
ATOM   5966  C CB  . ILE B 1 324 ? 186.341 183.077 153.787 1.00 96.14  ? 345 ILE B CB  1 
ATOM   5967  C CG1 . ILE B 1 324 ? 186.522 181.982 152.733 1.00 96.14  ? 345 ILE B CG1 1 
ATOM   5968  C CG2 . ILE B 1 324 ? 185.286 184.080 153.345 1.00 96.14  ? 345 ILE B CG2 1 
ATOM   5969  C CD1 . ILE B 1 324 ? 187.044 182.488 151.406 1.00 96.14  ? 345 ILE B CD1 1 
ATOM   5970  N N   . LEU B 1 325 ? 187.550 184.436 156.420 1.00 94.21  ? 346 LEU B N   1 
ATOM   5971  C CA  . LEU B 1 325 ? 187.550 185.417 157.501 1.00 94.21  ? 346 LEU B CA  1 
ATOM   5972  C C   . LEU B 1 325 ? 188.885 186.150 157.593 1.00 94.21  ? 346 LEU B C   1 
ATOM   5973  O O   . LEU B 1 325 ? 188.926 187.281 158.082 1.00 94.21  ? 346 LEU B O   1 
ATOM   5974  C CB  . LEU B 1 325 ? 187.210 184.753 158.836 1.00 94.21  ? 346 LEU B CB  1 
ATOM   5975  C CG  . LEU B 1 325 ? 185.752 184.707 159.316 1.00 94.21  ? 346 LEU B CG  1 
ATOM   5976  C CD1 . LEU B 1 325 ? 185.211 186.114 159.531 1.00 94.21  ? 346 LEU B CD1 1 
ATOM   5977  C CD2 . LEU B 1 325 ? 184.846 183.913 158.378 1.00 94.21  ? 346 LEU B CD2 1 
ATOM   5978  N N   . ARG B 1 326 ? 189.976 185.538 157.117 1.00 103.30 ? 347 ARG B N   1 
ATOM   5979  C CA  . ARG B 1 326 ? 191.247 186.254 157.020 1.00 103.30 ? 347 ARG B CA  1 
ATOM   5980  C C   . ARG B 1 326 ? 191.168 187.385 155.999 1.00 103.30 ? 347 ARG B C   1 
ATOM   5981  O O   . ARG B 1 326 ? 191.657 188.494 156.252 1.00 103.30 ? 347 ARG B O   1 
ATOM   5982  C CB  . ARG B 1 326 ? 192.374 185.284 156.661 1.00 103.30 ? 347 ARG B CB  1 
ATOM   5983  C CG  . ARG B 1 326 ? 193.739 185.927 156.491 1.00 103.30 ? 347 ARG B CG  1 
ATOM   5984  C CD  . ARG B 1 326 ? 194.743 184.942 155.912 1.00 103.30 ? 347 ARG B CD  1 
ATOM   5985  N NE  . ARG B 1 326 ? 194.772 183.684 156.649 1.00 103.30 ? 347 ARG B NE  1 
ATOM   5986  C CZ  . ARG B 1 326 ? 195.487 183.472 157.745 1.00 103.30 ? 347 ARG B CZ  1 
ATOM   5987  N NH1 . ARG B 1 326 ? 196.259 184.416 158.259 1.00 103.30 ? 347 ARG B NH1 1 
ATOM   5988  N NH2 . ARG B 1 326 ? 195.430 182.283 158.338 1.00 103.30 ? 347 ARG B NH2 1 
ATOM   5989  N N   . GLU B 1 327 ? 190.536 187.128 154.849 1.00 101.68 ? 348 GLU B N   1 
ATOM   5990  C CA  . GLU B 1 327 ? 190.284 188.195 153.883 1.00 101.68 ? 348 GLU B CA  1 
ATOM   5991  C C   . GLU B 1 327 ? 189.280 189.211 154.415 1.00 101.68 ? 348 GLU B C   1 
ATOM   5992  O O   . GLU B 1 327 ? 189.363 190.396 154.073 1.00 101.68 ? 348 GLU B O   1 
ATOM   5993  C CB  . GLU B 1 327 ? 189.786 187.609 152.561 1.00 101.68 ? 348 GLU B CB  1 
ATOM   5994  C CG  . GLU B 1 327 ? 190.758 186.661 151.876 1.00 101.68 ? 348 GLU B CG  1 
ATOM   5995  C CD  . GLU B 1 327 ? 192.201 187.109 152.000 1.00 101.68 ? 348 GLU B CD  1 
ATOM   5996  O OE1 . GLU B 1 327 ? 192.566 188.124 151.370 1.00 101.68 ? 348 GLU B OE1 1 
ATOM   5997  O OE2 . GLU B 1 327 ? 192.970 186.445 152.726 1.00 101.68 ? 348 GLU B OE2 1 
ATOM   5998  N N   . CYS B 1 328 ? 188.322 188.758 155.230 1.00 95.23  ? 349 CYS B N   1 
ATOM   5999  C CA  . CYS B 1 328 ? 187.361 189.663 155.854 1.00 95.23  ? 349 CYS B CA  1 
ATOM   6000  C C   . CYS B 1 328 ? 188.040 190.618 156.827 1.00 95.23  ? 349 CYS B C   1 
ATOM   6001  O O   . CYS B 1 328 ? 187.726 191.813 156.860 1.00 95.23  ? 349 CYS B O   1 
ATOM   6002  C CB  . CYS B 1 328 ? 186.275 188.855 156.564 1.00 95.23  ? 349 CYS B CB  1 
ATOM   6003  S SG  . CYS B 1 328 ? 185.256 189.794 157.728 1.00 95.23  ? 349 CYS B SG  1 
ATOM   6004  N N   . PHE B 1 329 ? 188.977 190.108 157.623 1.00 87.07  ? 350 PHE B N   1 
ATOM   6005  C CA  . PHE B 1 329 ? 189.681 190.949 158.580 1.00 87.07  ? 350 PHE B CA  1 
ATOM   6006  C C   . PHE B 1 329 ? 190.738 191.820 157.913 1.00 87.07  ? 350 PHE B C   1 
ATOM   6007  O O   . PHE B 1 329 ? 190.984 192.940 158.372 1.00 87.07  ? 350 PHE B O   1 
ATOM   6008  C CB  . PHE B 1 329 ? 190.321 190.084 159.668 1.00 87.07  ? 350 PHE B CB  1 
ATOM   6009  C CG  . PHE B 1 329 ? 189.429 189.843 160.853 1.00 87.07  ? 350 PHE B CG  1 
ATOM   6010  C CD1 . PHE B 1 329 ? 188.550 188.771 160.869 1.00 87.07  ? 350 PHE B CD1 1 
ATOM   6011  C CD2 . PHE B 1 329 ? 189.466 190.691 161.948 1.00 87.07  ? 350 PHE B CD2 1 
ATOM   6012  C CE1 . PHE B 1 329 ? 187.726 188.543 161.956 1.00 87.07  ? 350 PHE B CE1 1 
ATOM   6013  C CE2 . PHE B 1 329 ? 188.643 190.470 163.039 1.00 87.07  ? 350 PHE B CE2 1 
ATOM   6014  C CZ  . PHE B 1 329 ? 187.772 189.394 163.042 1.00 87.07  ? 350 PHE B CZ  1 
ATOM   6015  N N   . GLU B 1 330 ? 191.371 191.341 156.839 1.00 95.56  ? 351 GLU B N   1 
ATOM   6016  C CA  . GLU B 1 330 ? 192.472 192.106 156.254 1.00 95.56  ? 351 GLU B CA  1 
ATOM   6017  C C   . GLU B 1 330 ? 191.975 193.212 155.325 1.00 95.56  ? 351 GLU B C   1 
ATOM   6018  O O   . GLU B 1 330 ? 192.118 194.400 155.628 1.00 95.56  ? 351 GLU B O   1 
ATOM   6019  C CB  . GLU B 1 330 ? 193.420 191.164 155.504 1.00 95.56  ? 351 GLU B CB  1 
ATOM   6020  C CG  . GLU B 1 330 ? 194.463 190.493 156.378 1.00 95.56  ? 351 GLU B CG  1 
ATOM   6021  C CD  . GLU B 1 330 ? 195.001 189.219 155.760 1.00 95.56  ? 351 GLU B CD  1 
ATOM   6022  O OE1 . GLU B 1 330 ? 194.408 188.743 154.768 1.00 95.56  ? 351 GLU B OE1 1 
ATOM   6023  O OE2 . GLU B 1 330 ? 196.017 188.695 156.262 1.00 95.56  ? 351 GLU B OE2 1 
ATOM   6024  N N   . GLY B 1 331 ? 191.385 192.841 154.190 1.00 93.37  ? 352 GLY B N   1 
ATOM   6025  C CA  . GLY B 1 331 ? 191.011 193.844 153.212 1.00 93.37  ? 352 GLY B CA  1 
ATOM   6026  C C   . GLY B 1 331 ? 189.593 193.827 152.676 1.00 93.37  ? 352 GLY B C   1 
ATOM   6027  O O   . GLY B 1 331 ? 189.079 194.866 152.251 1.00 93.37  ? 352 GLY B O   1 
ATOM   6028  N N   . ASN B 1 332 ? 188.947 192.665 152.686 1.00 102.04 ? 353 ASN B N   1 
ATOM   6029  C CA  . ASN B 1 332 ? 187.740 192.437 151.890 1.00 102.04 ? 353 ASN B CA  1 
ATOM   6030  C C   . ASN B 1 332 ? 186.512 192.569 152.784 1.00 102.04 ? 353 ASN B C   1 
ATOM   6031  O O   . ASN B 1 332 ? 186.179 191.652 153.536 1.00 102.04 ? 353 ASN B O   1 
ATOM   6032  C CB  . ASN B 1 332 ? 187.786 191.063 151.226 1.00 102.04 ? 353 ASN B CB  1 
ATOM   6033  C CG  . ASN B 1 332 ? 188.872 190.950 150.166 1.00 102.04 ? 353 ASN B CG  1 
ATOM   6034  O OD1 . ASN B 1 332 ? 189.195 189.849 149.719 1.00 102.04 ? 353 ASN B OD1 1 
ATOM   6035  N ND2 . ASN B 1 332 ? 189.432 192.081 149.750 1.00 102.04 ? 353 ASN B ND2 1 
ATOM   6036  N N   . THR B 1 333 ? 185.816 193.702 152.682 1.00 89.26  ? 354 THR B N   1 
ATOM   6037  C CA  . THR B 1 333 ? 184.571 193.859 153.426 1.00 89.26  ? 354 THR B CA  1 
ATOM   6038  C C   . THR B 1 333 ? 183.421 193.079 152.804 1.00 89.26  ? 354 THR B C   1 
ATOM   6039  O O   . THR B 1 333 ? 182.403 192.865 153.472 1.00 89.26  ? 354 THR B O   1 
ATOM   6040  C CB  . THR B 1 333 ? 184.194 195.336 153.530 1.00 89.26  ? 354 THR B CB  1 
ATOM   6041  O OG1 . THR B 1 333 ? 184.055 195.893 152.218 1.00 89.26  ? 354 THR B OG1 1 
ATOM   6042  C CG2 . THR B 1 333 ? 185.258 196.100 154.292 1.00 89.26  ? 354 THR B CG2 1 
ATOM   6043  N N   . SER B 1 334 ? 183.555 192.654 151.545 1.00 85.14  ? 355 SER B N   1 
ATOM   6044  C CA  . SER B 1 334 ? 182.502 191.868 150.912 1.00 85.14  ? 355 SER B CA  1 
ATOM   6045  C C   . SER B 1 334 ? 182.464 190.441 151.444 1.00 85.14  ? 355 SER B C   1 
ATOM   6046  O O   . SER B 1 334 ? 181.406 189.802 151.423 1.00 85.14  ? 355 SER B O   1 
ATOM   6047  C CB  . SER B 1 334 ? 182.691 191.861 149.395 1.00 85.14  ? 355 SER B CB  1 
ATOM   6048  O OG  . SER B 1 334 ? 183.754 191.004 149.020 1.00 85.14  ? 355 SER B OG  1 
ATOM   6049  N N   . SER B 1 335 ? 183.597 189.925 151.920 1.00 83.78  ? 356 SER B N   1 
ATOM   6050  C CA  . SER B 1 335 ? 183.644 188.577 152.471 1.00 83.78  ? 356 SER B CA  1 
ATOM   6051  C C   . SER B 1 335 ? 183.046 188.483 153.868 1.00 83.78  ? 356 SER B C   1 
ATOM   6052  O O   . SER B 1 335 ? 182.755 187.373 154.325 1.00 83.78  ? 356 SER B O   1 
ATOM   6053  C CB  . SER B 1 335 ? 185.089 188.070 152.498 1.00 83.78  ? 356 SER B CB  1 
ATOM   6054  O OG  . SER B 1 335 ? 185.618 187.968 151.187 1.00 83.78  ? 356 SER B OG  1 
ATOM   6055  N N   . CYS B 1 336 ? 182.855 189.609 154.550 1.00 88.77  ? 357 CYS B N   1 
ATOM   6056  C CA  . CYS B 1 336 ? 182.281 189.604 155.888 1.00 88.77  ? 357 CYS B CA  1 
ATOM   6057  C C   . CYS B 1 336 ? 180.767 189.462 155.803 1.00 88.77  ? 357 CYS B C   1 
ATOM   6058  O O   . CYS B 1 336 ? 180.113 190.147 155.010 1.00 88.77  ? 357 CYS B O   1 
ATOM   6059  C CB  . CYS B 1 336 ? 182.654 190.886 156.630 1.00 88.77  ? 357 CYS B CB  1 
ATOM   6060  S SG  . CYS B 1 336 ? 184.421 191.264 156.604 1.00 88.77  ? 357 CYS B SG  1 
ATOM   6061  N N   . GLY B 1 337 ? 180.212 188.569 156.620 1.00 72.84  ? 358 GLY B N   1 
ATOM   6062  C CA  . GLY B 1 337 ? 178.787 188.324 156.621 1.00 72.84  ? 358 GLY B CA  1 
ATOM   6063  C C   . GLY B 1 337 ? 178.011 189.358 157.414 1.00 72.84  ? 358 GLY B C   1 
ATOM   6064  O O   . GLY B 1 337 ? 178.558 190.292 158.000 1.00 72.84  ? 358 GLY B O   1 
ATOM   6065  N N   . ARG B 1 338 ? 176.693 189.175 157.425 1.00 74.26  ? 359 ARG B N   1 
ATOM   6066  C CA  . ARG B 1 338 ? 175.797 190.066 158.146 1.00 74.26  ? 359 ARG B CA  1 
ATOM   6067  C C   . ARG B 1 338 ? 174.569 189.284 158.590 1.00 74.26  ? 359 ARG B C   1 
ATOM   6068  O O   . ARG B 1 338 ? 174.222 188.252 158.011 1.00 74.26  ? 359 ARG B O   1 
ATOM   6069  C CB  . ARG B 1 338 ? 175.385 191.265 157.284 1.00 74.26  ? 359 ARG B CB  1 
ATOM   6070  C CG  . ARG B 1 338 ? 174.746 190.870 155.966 1.00 74.26  ? 359 ARG B CG  1 
ATOM   6071  C CD  . ARG B 1 338 ? 174.183 192.066 155.221 1.00 74.26  ? 359 ARG B CD  1 
ATOM   6072  N NE  . ARG B 1 338 ? 173.612 191.673 153.938 1.00 74.26  ? 359 ARG B NE  1 
ATOM   6073  C CZ  . ARG B 1 338 ? 172.870 192.462 153.173 1.00 74.26  ? 359 ARG B CZ  1 
ATOM   6074  N NH1 . ARG B 1 338 ? 172.568 193.696 153.541 1.00 74.26  ? 359 ARG B NH1 1 
ATOM   6075  N NH2 . ARG B 1 338 ? 172.415 191.999 152.013 1.00 74.26  ? 359 ARG B NH2 1 
ATOM   6076  N N   . GLU B 1 339 ? 173.915 189.792 159.632 1.00 72.03  ? 360 GLU B N   1 
ATOM   6077  C CA  . GLU B 1 339 ? 172.706 189.176 160.155 1.00 72.03  ? 360 GLU B CA  1 
ATOM   6078  C C   . GLU B 1 339 ? 171.686 190.260 160.477 1.00 72.03  ? 360 GLU B C   1 
ATOM   6079  O O   . GLU B 1 339 ? 172.031 191.421 160.710 1.00 72.03  ? 360 GLU B O   1 
ATOM   6080  C CB  . GLU B 1 339 ? 173.002 188.306 161.388 1.00 72.03  ? 360 GLU B CB  1 
ATOM   6081  C CG  . GLU B 1 339 ? 173.196 189.067 162.688 1.00 72.03  ? 360 GLU B CG  1 
ATOM   6082  C CD  . GLU B 1 339 ? 173.829 188.212 163.769 1.00 72.03  ? 360 GLU B CD  1 
ATOM   6083  O OE1 . GLU B 1 339 ? 174.279 187.091 163.454 1.00 72.03  ? 360 GLU B OE1 1 
ATOM   6084  O OE2 . GLU B 1 339 ? 173.879 188.662 164.934 1.00 72.03  ? 360 GLU B OE2 1 
ATOM   6085  N N   . MET B 1 340 ? 170.417 189.859 160.480 1.00 80.16  ? 361 MET B N   1 
ATOM   6086  C CA  . MET B 1 340 ? 169.286 190.769 160.613 1.00 80.16  ? 361 MET B CA  1 
ATOM   6087  C C   . MET B 1 340 ? 168.754 190.740 162.039 1.00 80.16  ? 361 MET B C   1 
ATOM   6088  O O   . MET B 1 340 ? 168.575 189.663 162.615 1.00 80.16  ? 361 MET B O   1 
ATOM   6089  C CB  . MET B 1 340 ? 168.177 190.383 159.631 1.00 80.16  ? 361 MET B CB  1 
ATOM   6090  C CG  . MET B 1 340 ? 166.969 191.306 159.633 1.00 80.16  ? 361 MET B CG  1 
ATOM   6091  S SD  . MET B 1 340 ? 165.751 190.830 158.391 1.00 80.16  ? 361 MET B SD  1 
ATOM   6092  C CE  . MET B 1 340 ? 164.441 192.005 158.721 1.00 80.16  ? 361 MET B CE  1 
ATOM   6093  N N   . VAL B 1 341 ? 168.522 191.924 162.615 1.00 76.61  ? 362 VAL B N   1 
ATOM   6094  C CA  . VAL B 1 341 ? 167.904 192.056 163.928 1.00 76.61  ? 362 VAL B CA  1 
ATOM   6095  C C   . VAL B 1 341 ? 166.810 193.115 163.861 1.00 76.61  ? 362 VAL B C   1 
ATOM   6096  O O   . VAL B 1 341 ? 166.791 193.971 162.973 1.00 76.61  ? 362 VAL B O   1 
ATOM   6097  C CB  . VAL B 1 341 ? 168.917 192.419 165.042 1.00 76.61  ? 362 VAL B CB  1 
ATOM   6098  C CG1 . VAL B 1 341 ? 169.932 191.300 165.268 1.00 76.61  ? 362 VAL B CG1 1 
ATOM   6099  C CG2 . VAL B 1 341 ? 169.625 193.725 164.716 1.00 76.61  ? 362 VAL B CG2 1 
ATOM   6100  N N   . LEU B 1 342 ? 165.880 193.036 164.816 1.00 90.23  ? 363 LEU B N   1 
ATOM   6101  C CA  . LEU B 1 342 ? 164.902 194.096 165.022 1.00 90.23  ? 363 LEU B CA  1 
ATOM   6102  C C   . LEU B 1 342 ? 164.690 194.420 166.494 1.00 90.23  ? 363 LEU B C   1 
ATOM   6103  O O   . LEU B 1 342 ? 163.863 195.285 166.802 1.00 90.23  ? 363 LEU B O   1 
ATOM   6104  C CB  . LEU B 1 342 ? 163.536 193.748 164.391 1.00 90.23  ? 363 LEU B CB  1 
ATOM   6105  C CG  . LEU B 1 342 ? 162.577 192.717 165.006 1.00 90.23  ? 363 LEU B CG  1 
ATOM   6106  C CD1 . LEU B 1 342 ? 161.192 192.894 164.401 1.00 90.23  ? 363 LEU B CD1 1 
ATOM   6107  C CD2 . LEU B 1 342 ? 163.031 191.279 164.819 1.00 90.23  ? 363 LEU B CD2 1 
ATOM   6108  N N   . ASN B 1 343 ? 165.397 193.755 167.404 1.00 98.02  ? 364 ASN B N   1 
ATOM   6109  C CA  . ASN B 1 343 ? 165.253 193.987 168.832 1.00 98.02  ? 364 ASN B CA  1 
ATOM   6110  C C   . ASN B 1 343 ? 165.819 195.350 169.227 1.00 98.02  ? 364 ASN B C   1 
ATOM   6111  O O   . ASN B 1 343 ? 166.635 195.948 168.520 1.00 98.02  ? 364 ASN B O   1 
ATOM   6112  C CB  . ASN B 1 343 ? 165.939 192.867 169.616 1.00 98.02  ? 364 ASN B CB  1 
ATOM   6113  C CG  . ASN B 1 343 ? 167.295 192.502 169.040 1.00 98.02  ? 364 ASN B CG  1 
ATOM   6114  O OD1 . ASN B 1 343 ? 167.796 193.168 168.137 1.00 98.02  ? 364 ASN B OD1 1 
ATOM   6115  N ND2 . ASN B 1 343 ? 167.884 191.425 169.545 1.00 98.02  ? 364 ASN B ND2 1 
ATOM   6116  N N   . SER B 1 344 ? 165.367 195.841 170.381 1.00 93.88  ? 365 SER B N   1 
ATOM   6117  C CA  . SER B 1 344 ? 165.669 197.201 170.804 1.00 93.88  ? 365 SER B CA  1 
ATOM   6118  C C   . SER B 1 344 ? 167.015 197.345 171.501 1.00 93.88  ? 365 SER B C   1 
ATOM   6119  O O   . SER B 1 344 ? 167.513 198.470 171.619 1.00 93.88  ? 365 SER B O   1 
ATOM   6120  C CB  . SER B 1 344 ? 164.571 197.716 171.739 1.00 93.88  ? 365 SER B CB  1 
ATOM   6121  O OG  . SER B 1 344 ? 164.567 196.998 172.960 1.00 93.88  ? 365 SER B OG  1 
ATOM   6122  N N   . TYR B 1 345 ? 167.618 196.253 171.963 1.00 82.59  ? 366 TYR B N   1 
ATOM   6123  C CA  . TYR B 1 345 ? 168.870 196.345 172.717 1.00 82.59  ? 366 TYR B CA  1 
ATOM   6124  C C   . TYR B 1 345 ? 170.097 196.197 171.816 1.00 82.59  ? 366 TYR B C   1 
ATOM   6125  O O   . TYR B 1 345 ? 171.025 195.437 172.085 1.00 82.59  ? 366 TYR B O   1 
ATOM   6126  C CB  . TYR B 1 345 ? 168.880 195.333 173.866 1.00 82.59  ? 366 TYR B CB  1 
ATOM   6127  C CG  . TYR B 1 345 ? 168.822 193.841 173.535 1.00 82.59  ? 366 TYR B CG  1 
ATOM   6128  C CD1 . TYR B 1 345 ? 167.661 193.246 173.043 1.00 82.59  ? 366 TYR B CD1 1 
ATOM   6129  C CD2 . TYR B 1 345 ? 169.922 193.019 173.777 1.00 82.59  ? 366 TYR B CD2 1 
ATOM   6130  C CE1 . TYR B 1 345 ? 167.613 191.891 172.767 1.00 82.59  ? 366 TYR B CE1 1 
ATOM   6131  C CE2 . TYR B 1 345 ? 169.882 191.664 173.500 1.00 82.59  ? 366 TYR B CE2 1 
ATOM   6132  C CZ  . TYR B 1 345 ? 168.726 191.106 172.996 1.00 82.59  ? 366 TYR B CZ  1 
ATOM   6133  O OH  . TYR B 1 345 ? 168.682 189.759 172.723 1.00 82.59  ? 366 TYR B OH  1 
ATOM   6134  N N   . ILE B 1 346 ? 170.131 196.978 170.746 1.00 73.21  ? 367 ILE B N   1 
ATOM   6135  C CA  . ILE B 1 346 ? 171.267 197.025 169.832 1.00 73.21  ? 367 ILE B CA  1 
ATOM   6136  C C   . ILE B 1 346 ? 171.923 198.393 169.976 1.00 73.21  ? 367 ILE B C   1 
ATOM   6137  O O   . ILE B 1 346 ? 171.253 199.415 169.771 1.00 73.21  ? 367 ILE B O   1 
ATOM   6138  C CB  . ILE B 1 346 ? 170.842 196.769 168.379 1.00 73.21  ? 367 ILE B CB  1 
ATOM   6139  C CG1 . ILE B 1 346 ? 170.252 195.367 168.239 1.00 73.21  ? 367 ILE B CG1 1 
ATOM   6140  C CG2 . ILE B 1 346 ? 172.028 196.934 167.446 1.00 73.21  ? 367 ILE B CG2 1 
ATOM   6141  C CD1 . ILE B 1 346 ? 171.179 194.260 168.682 1.00 73.21  ? 367 ILE B CD1 1 
ATOM   6142  N N   . PRO B 1 347 ? 173.200 198.467 170.353 1.00 71.58  ? 368 PRO B N   1 
ATOM   6143  C CA  . PRO B 1 347 ? 173.873 199.770 170.427 1.00 71.58  ? 368 PRO B CA  1 
ATOM   6144  C C   . PRO B 1 347 ? 174.076 200.371 169.045 1.00 71.58  ? 368 PRO B C   1 
ATOM   6145  O O   . PRO B 1 347 ? 174.283 199.658 168.060 1.00 71.58  ? 368 PRO B O   1 
ATOM   6146  C CB  . PRO B 1 347 ? 175.211 199.442 171.099 1.00 71.58  ? 368 PRO B CB  1 
ATOM   6147  C CG  . PRO B 1 347 ? 175.438 198.000 170.800 1.00 71.58  ? 368 PRO B CG  1 
ATOM   6148  C CD  . PRO B 1 347 ? 174.082 197.360 170.760 1.00 71.58  ? 368 PRO B CD  1 
ATOM   6149  N N   . LEU B 1 348 ? 174.010 201.700 168.981 1.00 58.32  ? 369 LEU B N   1 
ATOM   6150  C CA  . LEU B 1 348 ? 174.086 202.416 167.719 1.00 58.32  ? 369 LEU B CA  1 
ATOM   6151  C C   . LEU B 1 348 ? 175.233 203.411 167.642 1.00 58.32  ? 369 LEU B C   1 
ATOM   6152  O O   . LEU B 1 348 ? 175.445 203.999 166.576 1.00 58.32  ? 369 LEU B O   1 
ATOM   6153  C CB  . LEU B 1 348 ? 172.764 203.151 167.448 1.00 58.32  ? 369 LEU B CB  1 
ATOM   6154  C CG  . LEU B 1 348 ? 171.553 202.240 167.235 1.00 58.32  ? 369 LEU B CG  1 
ATOM   6155  C CD1 . LEU B 1 348 ? 170.277 202.909 167.718 1.00 58.32  ? 369 LEU B CD1 1 
ATOM   6156  C CD2 . LEU B 1 348 ? 171.433 201.841 165.774 1.00 58.32  ? 369 LEU B CD2 1 
ATOM   6157  N N   . TYR B 1 349 ? 175.975 203.617 168.727 1.00 46.88  ? 370 TYR B N   1 
ATOM   6158  C CA  . TYR B 1 349 ? 177.113 204.523 168.719 1.00 46.88  ? 370 TYR B CA  1 
ATOM   6159  C C   . TYR B 1 349 ? 178.149 204.013 169.705 1.00 46.88  ? 370 TYR B C   1 
ATOM   6160  O O   . TYR B 1 349 ? 177.825 203.310 170.666 1.00 46.88  ? 370 TYR B O   1 
ATOM   6161  C CB  . TYR B 1 349 ? 176.700 205.961 169.067 1.00 46.88  ? 370 TYR B CB  1 
ATOM   6162  C CG  . TYR B 1 349 ? 176.407 206.193 170.536 1.00 46.88  ? 370 TYR B CG  1 
ATOM   6163  C CD1 . TYR B 1 349 ? 175.210 205.765 171.099 1.00 46.88  ? 370 TYR B CD1 1 
ATOM   6164  C CD2 . TYR B 1 349 ? 177.320 206.853 171.356 1.00 46.88  ? 370 TYR B CD2 1 
ATOM   6165  C CE1 . TYR B 1 349 ? 174.933 205.978 172.438 1.00 46.88  ? 370 TYR B CE1 1 
ATOM   6166  C CE2 . TYR B 1 349 ? 177.053 207.068 172.696 1.00 46.88  ? 370 TYR B CE2 1 
ATOM   6167  C CZ  . TYR B 1 349 ? 175.858 206.628 173.230 1.00 46.88  ? 370 TYR B CZ  1 
ATOM   6168  O OH  . TYR B 1 349 ? 175.584 206.840 174.562 1.00 46.88  ? 370 TYR B OH  1 
ATOM   6169  N N   . ALA B 1 350 ? 179.404 204.387 169.465 1.00 41.04  ? 371 ALA B N   1 
ATOM   6170  C CA  . ALA B 1 350 ? 180.484 204.023 170.372 1.00 41.04  ? 371 ALA B CA  1 
ATOM   6171  C C   . ALA B 1 350 ? 181.606 205.050 170.277 1.00 41.04  ? 371 ALA B C   1 
ATOM   6172  O O   . ALA B 1 350 ? 181.674 205.854 169.338 1.00 41.04  ? 371 ALA B O   1 
ATOM   6173  C CB  . ALA B 1 350 ? 181.006 202.613 170.087 1.00 41.04  ? 371 ALA B CB  1 
ATOM   6174  N N   . LEU B 1 351 ? 182.502 204.995 171.262 1.00 34.46  ? 372 LEU B N   1 
ATOM   6175  C CA  . LEU B 1 351 ? 183.601 205.937 171.415 1.00 34.46  ? 372 LEU B CA  1 
ATOM   6176  C C   . LEU B 1 351 ? 184.905 205.157 171.401 1.00 34.46  ? 372 LEU B C   1 
ATOM   6177  O O   . LEU B 1 351 ? 185.011 204.112 172.048 1.00 34.46  ? 372 LEU B O   1 
ATOM   6178  C CB  . LEU B 1 351 ? 183.459 206.735 172.723 1.00 34.46  ? 372 LEU B CB  1 
ATOM   6179  C CG  . LEU B 1 351 ? 184.281 208.001 173.003 1.00 34.46  ? 372 LEU B CG  1 
ATOM   6180  C CD1 . LEU B 1 351 ? 183.470 208.956 173.859 1.00 34.46  ? 372 LEU B CD1 1 
ATOM   6181  C CD2 . LEU B 1 351 ? 185.590 207.707 173.701 1.00 34.46  ? 372 LEU B CD2 1 
ATOM   6182  N N   . SER B 1 352 ? 185.889 205.663 170.663 1.00 40.35  ? 373 SER B N   1 
ATOM   6183  C CA  . SER B 1 352 ? 187.215 205.060 170.600 1.00 40.35  ? 373 SER B CA  1 
ATOM   6184  C C   . SER B 1 352 ? 188.231 206.155 170.318 1.00 40.35  ? 373 SER B C   1 
ATOM   6185  O O   . SER B 1 352 ? 188.185 206.773 169.248 1.00 40.35  ? 373 SER B O   1 
ATOM   6186  C CB  . SER B 1 352 ? 187.279 203.972 169.524 1.00 40.35  ? 373 SER B CB  1 
ATOM   6187  O OG  . SER B 1 352 ? 187.554 204.531 168.253 1.00 40.35  ? 373 SER B OG  1 
ATOM   6188  N N   . GLU B 1 353 ? 189.136 206.380 171.284 1.00 44.79  ? 374 GLU B N   1 
ATOM   6189  C CA  . GLU B 1 353 ? 190.223 207.370 171.212 1.00 44.79  ? 374 GLU B CA  1 
ATOM   6190  C C   . GLU B 1 353 ? 189.701 208.783 170.950 1.00 44.79  ? 374 GLU B C   1 
ATOM   6191  O O   . GLU B 1 353 ? 190.284 209.545 170.176 1.00 44.79  ? 374 GLU B O   1 
ATOM   6192  C CB  . GLU B 1 353 ? 191.272 206.976 170.166 1.00 44.79  ? 374 GLU B CB  1 
ATOM   6193  C CG  . GLU B 1 353 ? 192.167 205.823 170.584 1.00 44.79  ? 374 GLU B CG  1 
ATOM   6194  C CD  . GLU B 1 353 ? 191.632 204.480 170.130 1.00 44.79  ? 374 GLU B CD  1 
ATOM   6195  O OE1 . GLU B 1 353 ? 190.705 204.461 169.293 1.00 44.79  ? 374 GLU B OE1 1 
ATOM   6196  O OE2 . GLU B 1 353 ? 192.137 203.444 170.610 1.00 44.79  ? 374 GLU B OE2 1 
ATOM   6197  N N   . GLY B 1 354 ? 188.595 209.137 171.601 1.00 41.94  ? 375 GLY B N   1 
ATOM   6198  C CA  . GLY B 1 354 ? 187.969 210.422 171.351 1.00 41.94  ? 375 GLY B CA  1 
ATOM   6199  C C   . GLY B 1 354 ? 187.274 210.521 170.015 1.00 41.94  ? 375 GLY B C   1 
ATOM   6200  O O   . GLY B 1 354 ? 187.042 211.627 169.522 1.00 41.94  ? 375 GLY B O   1 
ATOM   6201  N N   . VAL B 1 355 ? 186.930 209.385 169.419 1.00 41.88  ? 376 VAL B N   1 
ATOM   6202  C CA  . VAL B 1 355 ? 186.374 209.301 168.075 1.00 41.88  ? 376 VAL B CA  1 
ATOM   6203  C C   . VAL B 1 355 ? 185.016 208.622 168.170 1.00 41.88  ? 376 VAL B C   1 
ATOM   6204  O O   . VAL B 1 355 ? 184.918 207.509 168.696 1.00 41.88  ? 376 VAL B O   1 
ATOM   6205  C CB  . VAL B 1 355 ? 187.318 208.519 167.145 1.00 41.88  ? 376 VAL B CB  1 
ATOM   6206  C CG1 . VAL B 1 355 ? 186.643 208.194 165.846 1.00 41.88  ? 376 VAL B CG1 1 
ATOM   6207  C CG2 . VAL B 1 355 ? 188.595 209.310 166.899 1.00 41.88  ? 376 VAL B CG2 1 
ATOM   6208  N N   . ILE B 1 356 ? 183.973 209.277 167.669 1.00 42.04  ? 377 ILE B N   1 
ATOM   6209  C CA  . ILE B 1 356 ? 182.618 208.750 167.769 1.00 42.04  ? 377 ILE B CA  1 
ATOM   6210  C C   . ILE B 1 356 ? 182.255 208.068 166.461 1.00 42.04  ? 377 ILE B C   1 
ATOM   6211  O O   . ILE B 1 356 ? 182.255 208.700 165.397 1.00 42.04  ? 377 ILE B O   1 
ATOM   6212  C CB  . ILE B 1 356 ? 181.609 209.853 168.116 1.00 42.04  ? 377 ILE B CB  1 
ATOM   6213  C CG1 . ILE B 1 356 ? 181.836 210.349 169.538 1.00 42.04  ? 377 ILE B CG1 1 
ATOM   6214  C CG2 . ILE B 1 356 ? 180.187 209.344 167.969 1.00 42.04  ? 377 ILE B CG2 1 
ATOM   6215  C CD1 . ILE B 1 356 ? 181.731 209.256 170.563 1.00 42.04  ? 377 ILE B CD1 1 
ATOM   6216  N N   . TYR B 1 357 ? 181.948 206.778 166.539 1.00 39.57  ? 378 TYR B N   1 
ATOM   6217  C CA  . TYR B 1 357 ? 181.345 206.050 165.430 1.00 39.57  ? 378 TYR B CA  1 
ATOM   6218  C C   . TYR B 1 357 ? 179.857 205.949 165.732 1.00 39.57  ? 378 TYR B C   1 
ATOM   6219  O O   . TYR B 1 357 ? 179.456 205.237 166.659 1.00 39.57  ? 378 TYR B O   1 
ATOM   6220  C CB  . TYR B 1 357 ? 181.978 204.671 165.265 1.00 39.57  ? 378 TYR B CB  1 
ATOM   6221  C CG  . TYR B 1 357 ? 183.404 204.703 164.768 1.00 39.57  ? 378 TYR B CG  1 
ATOM   6222  C CD1 . TYR B 1 357 ? 183.868 205.758 163.992 1.00 39.57  ? 378 TYR B CD1 1 
ATOM   6223  C CD2 . TYR B 1 357 ? 184.290 203.682 165.082 1.00 39.57  ? 378 TYR B CD2 1 
ATOM   6224  C CE1 . TYR B 1 357 ? 185.171 205.788 163.535 1.00 39.57  ? 378 TYR B CE1 1 
ATOM   6225  C CE2 . TYR B 1 357 ? 185.597 203.704 164.633 1.00 39.57  ? 378 TYR B CE2 1 
ATOM   6226  C CZ  . TYR B 1 357 ? 186.031 204.760 163.860 1.00 39.57  ? 378 TYR B CZ  1 
ATOM   6227  O OH  . TYR B 1 357 ? 187.330 204.789 163.409 1.00 39.57  ? 378 TYR B OH  1 
ATOM   6228  N N   . ALA B 1 358 ? 179.041 206.682 164.974 1.00 53.10  ? 379 ALA B N   1 
ATOM   6229  C CA  . ALA B 1 358 ? 177.624 206.782 165.293 1.00 53.10  ? 379 ALA B CA  1 
ATOM   6230  C C   . ALA B 1 358 ? 176.773 206.553 164.057 1.00 53.10  ? 379 ALA B C   1 
ATOM   6231  O O   . ALA B 1 358 ? 177.046 207.109 162.991 1.00 53.10  ? 379 ALA B O   1 
ATOM   6232  C CB  . ALA B 1 358 ? 177.285 208.149 165.899 1.00 53.10  ? 379 ALA B CB  1 
ATOM   6233  N N   . ASN B 1 359 ? 175.729 205.741 164.214 1.00 59.41  ? 380 ASN B N   1 
ATOM   6234  C CA  . ASN B 1 359 ? 174.713 205.561 163.181 1.00 59.41  ? 380 ASN B CA  1 
ATOM   6235  C C   . ASN B 1 359 ? 173.696 206.682 163.349 1.00 59.41  ? 380 ASN B C   1 
ATOM   6236  O O   . ASN B 1 359 ? 172.801 206.604 164.194 1.00 59.41  ? 380 ASN B O   1 
ATOM   6237  C CB  . ASN B 1 359 ? 174.062 204.188 163.294 1.00 59.41  ? 380 ASN B CB  1 
ATOM   6238  C CG  . ASN B 1 359 ? 173.250 203.822 162.068 1.00 59.41  ? 380 ASN B CG  1 
ATOM   6239  O OD1 . ASN B 1 359 ? 173.220 204.559 161.083 1.00 59.41  ? 380 ASN B OD1 1 
ATOM   6240  N ND2 . ASN B 1 359 ? 172.581 202.676 162.124 1.00 59.41  ? 380 ASN B ND2 1 
ATOM   6241  N N   . CYS B 1 360 ? 173.829 207.729 162.540 1.00 63.71  ? 381 CYS B N   1 
ATOM   6242  C CA  . CYS B 1 360 ? 172.995 208.915 162.674 1.00 63.71  ? 381 CYS B CA  1 
ATOM   6243  C C   . CYS B 1 360 ? 171.672 208.808 161.926 1.00 63.71  ? 381 CYS B C   1 
ATOM   6244  O O   . CYS B 1 360 ? 170.882 209.757 161.959 1.00 63.71  ? 381 CYS B O   1 
ATOM   6245  C CB  . CYS B 1 360 ? 173.759 210.155 162.200 1.00 63.71  ? 381 CYS B CB  1 
ATOM   6246  S SG  . CYS B 1 360 ? 175.102 210.657 163.303 1.00 63.71  ? 381 CYS B SG  1 
ATOM   6247  N N   . LEU B 1 361 ? 171.413 207.686 161.251 1.00 68.79  ? 382 LEU B N   1 
ATOM   6248  C CA  . LEU B 1 361 ? 170.132 207.514 160.574 1.00 68.79  ? 382 LEU B CA  1 
ATOM   6249  C C   . LEU B 1 361 ? 169.013 207.228 161.567 1.00 68.79  ? 382 LEU B C   1 
ATOM   6250  O O   . LEU B 1 361 ? 167.908 207.766 161.437 1.00 68.79  ? 382 LEU B O   1 
ATOM   6251  C CB  . LEU B 1 361 ? 170.234 206.396 159.537 1.00 68.79  ? 382 LEU B CB  1 
ATOM   6252  C CG  . LEU B 1 361 ? 169.044 206.232 158.589 1.00 68.79  ? 382 LEU B CG  1 
ATOM   6253  C CD1 . LEU B 1 361 ? 168.737 207.541 157.880 1.00 68.79  ? 382 LEU B CD1 1 
ATOM   6254  C CD2 . LEU B 1 361 ? 169.316 205.130 157.579 1.00 68.79  ? 382 LEU B CD2 1 
ATOM   6255  N N   . ALA B 1 362 ? 169.280 206.386 162.566 1.00 69.14  ? 383 ALA B N   1 
ATOM   6256  C CA  . ALA B 1 362 ? 168.270 206.032 163.555 1.00 69.14  ? 383 ALA B CA  1 
ATOM   6257  C C   . ALA B 1 362 ? 168.336 206.898 164.804 1.00 69.14  ? 383 ALA B C   1 
ATOM   6258  O O   . ALA B 1 362 ? 167.298 207.156 165.425 1.00 69.14  ? 383 ALA B O   1 
ATOM   6259  C CB  . ALA B 1 362 ? 168.409 204.559 163.947 1.00 69.14  ? 383 ALA B CB  1 
ATOM   6260  N N   . THR B 1 363 ? 169.526 207.349 165.187 1.00 64.63  ? 384 THR B N   1 
ATOM   6261  C CA  . THR B 1 363 ? 169.723 208.179 166.367 1.00 64.63  ? 384 THR B CA  1 
ATOM   6262  C C   . THR B 1 363 ? 170.026 209.603 165.922 1.00 64.63  ? 384 THR B C   1 
ATOM   6263  O O   . THR B 1 363 ? 170.819 209.809 164.998 1.00 64.63  ? 384 THR B O   1 
ATOM   6264  C CB  . THR B 1 363 ? 170.864 207.632 167.229 1.00 64.63  ? 384 THR B CB  1 
ATOM   6265  O OG1 . THR B 1 363 ? 170.677 206.226 167.430 1.00 64.63  ? 384 THR B OG1 1 
ATOM   6266  C CG2 . THR B 1 363 ? 170.894 208.317 168.583 1.00 64.63  ? 384 THR B CG2 1 
ATOM   6267  N N   . SER B 1 364 ? 169.384 210.577 166.564 1.00 71.26  ? 385 SER B N   1 
ATOM   6268  C CA  . SER B 1 364 ? 169.577 211.973 166.192 1.00 71.26  ? 385 SER B CA  1 
ATOM   6269  C C   . SER B 1 364 ? 170.960 212.455 166.612 1.00 71.26  ? 385 SER B C   1 
ATOM   6270  O O   . SER B 1 364 ? 171.377 212.266 167.759 1.00 71.26  ? 385 SER B O   1 
ATOM   6271  C CB  . SER B 1 364 ? 168.496 212.844 166.829 1.00 71.26  ? 385 SER B CB  1 
ATOM   6272  O OG  . SER B 1 364 ? 168.741 214.217 166.584 1.00 71.26  ? 385 SER B OG  1 
ATOM   6273  N N   . CYS B 1 365 ? 171.670 213.081 165.676 1.00 72.78  ? 386 CYS B N   1 
ATOM   6274  C CA  . CYS B 1 365 ? 173.015 213.594 165.903 1.00 72.78  ? 386 CYS B CA  1 
ATOM   6275  C C   . CYS B 1 365 ? 173.003 215.105 165.736 1.00 72.78  ? 386 CYS B C   1 
ATOM   6276  O O   . CYS B 1 365 ? 172.497 215.617 164.732 1.00 72.78  ? 386 CYS B O   1 
ATOM   6277  C CB  . CYS B 1 365 ? 174.015 212.967 164.928 1.00 72.78  ? 386 CYS B CB  1 
ATOM   6278  S SG  . CYS B 1 365 ? 174.167 211.170 165.033 1.00 72.78  ? 386 CYS B SG  1 
ATOM   6279  N N   . LYS B 1 366 ? 173.559 215.817 166.715 1.00 80.99  ? 387 LYS B N   1 
ATOM   6280  C CA  . LYS B 1 366 ? 173.618 217.271 166.664 1.00 80.99  ? 387 LYS B CA  1 
ATOM   6281  C C   . LYS B 1 366 ? 174.944 217.745 167.241 1.00 80.99  ? 387 LYS B C   1 
ATOM   6282  O O   . LYS B 1 366 ? 175.723 216.964 167.786 1.00 80.99  ? 387 LYS B O   1 
ATOM   6283  C CB  . LYS B 1 366 ? 172.449 217.911 167.424 1.00 80.99  ? 387 LYS B CB  1 
ATOM   6284  C CG  . LYS B 1 366 ? 171.195 218.120 166.583 1.00 80.99  ? 387 LYS B CG  1 
ATOM   6285  C CD  . LYS B 1 366 ? 169.991 218.557 167.418 1.00 80.99  ? 387 LYS B CD  1 
ATOM   6286  C CE  . LYS B 1 366 ? 170.347 219.629 168.443 1.00 80.99  ? 387 LYS B CE  1 
ATOM   6287  N NZ  . LYS B 1 366 ? 170.718 220.917 167.793 1.00 80.99  ? 387 LYS B NZ  1 
ATOM   6288  N N   . CYS B 1 367 ? 175.189 219.047 167.132 1.00 80.47  ? 388 CYS B N   1 
ATOM   6289  C CA  . CYS B 1 367 ? 176.351 219.685 167.735 1.00 80.47  ? 388 CYS B CA  1 
ATOM   6290  C C   . CYS B 1 367 ? 175.885 220.807 168.648 1.00 80.47  ? 388 CYS B C   1 
ATOM   6291  O O   . CYS B 1 367 ? 175.066 221.636 168.246 1.00 80.47  ? 388 CYS B O   1 
ATOM   6292  C CB  . CYS B 1 367 ? 177.303 220.225 166.666 1.00 80.47  ? 388 CYS B CB  1 
ATOM   6293  S SG  . CYS B 1 367 ? 177.961 218.958 165.566 1.00 80.47  ? 388 CYS B SG  1 
ATOM   6294  N N   . ALA B 1 368 ? 176.403 220.829 169.876 1.00 71.96  ? 389 ALA B N   1 
ATOM   6295  C CA  . ALA B 1 368 ? 175.962 221.824 170.847 1.00 71.96  ? 389 ALA B CA  1 
ATOM   6296  C C   . ALA B 1 368 ? 176.564 223.199 170.591 1.00 71.96  ? 389 ALA B C   1 
ATOM   6297  O O   . ALA B 1 368 ? 175.958 224.211 170.958 1.00 71.96  ? 389 ALA B O   1 
ATOM   6298  C CB  . ALA B 1 368 ? 176.305 221.368 172.263 1.00 71.96  ? 389 ALA B CB  1 
ATOM   6299  N N   . THR B 1 369 ? 177.749 223.257 169.979 1.00 73.57  ? 390 THR B N   1 
ATOM   6300  C CA  . THR B 1 369 ? 178.422 224.534 169.775 1.00 73.57  ? 390 THR B CA  1 
ATOM   6301  C C   . THR B 1 369 ? 177.772 225.365 168.676 1.00 73.57  ? 390 THR B C   1 
ATOM   6302  O O   . THR B 1 369 ? 177.832 226.598 168.722 1.00 73.57  ? 390 THR B O   1 
ATOM   6303  C CB  . THR B 1 369 ? 179.897 224.305 169.445 1.00 73.57  ? 390 THR B CB  1 
ATOM   6304  O OG1 . THR B 1 369 ? 180.004 223.394 168.344 1.00 73.57  ? 390 THR B OG1 1 
ATOM   6305  C CG2 . THR B 1 369 ? 180.626 223.725 170.647 1.00 73.57  ? 390 THR B CG2 1 
ATOM   6306  N N   . THR B 1 370 ? 177.151 224.718 167.689 1.00 74.91  ? 391 THR B N   1 
ATOM   6307  C CA  . THR B 1 370 ? 176.564 225.414 166.554 1.00 74.91  ? 391 THR B CA  1 
ATOM   6308  C C   . THR B 1 370 ? 175.056 225.258 166.434 1.00 74.91  ? 391 THR B C   1 
ATOM   6309  O O   . THR B 1 370 ? 174.434 226.075 165.744 1.00 74.91  ? 391 THR B O   1 
ATOM   6310  C CB  . THR B 1 370 ? 177.204 224.932 165.243 1.00 74.91  ? 391 THR B CB  1 
ATOM   6311  O OG1 . THR B 1 370 ? 177.116 223.504 165.171 1.00 74.91  ? 391 THR B OG1 1 
ATOM   6312  C CG2 . THR B 1 370 ? 178.664 225.350 165.176 1.00 74.91  ? 391 THR B CG2 1 
ATOM   6313  N N   . ASN B 1 371 ? 174.468 224.241 167.078 1.00 78.29  ? 392 ASN B N   1 
ATOM   6314  C CA  . ASN B 1 371 ? 173.032 223.927 167.060 1.00 78.29  ? 392 ASN B CA  1 
ATOM   6315  C C   . ASN B 1 371 ? 172.525 223.708 165.630 1.00 78.29  ? 392 ASN B C   1 
ATOM   6316  O O   . ASN B 1 371 ? 171.667 224.429 165.118 1.00 78.29  ? 392 ASN B O   1 
ATOM   6317  C CB  . ASN B 1 371 ? 172.216 224.997 167.801 1.00 78.29  ? 392 ASN B CB  1 
ATOM   6318  C CG  . ASN B 1 371 ? 170.793 224.554 168.088 1.00 78.29  ? 392 ASN B CG  1 
ATOM   6319  O OD1 . ASN B 1 371 ? 170.538 223.379 168.351 1.00 78.29  ? 392 ASN B OD1 1 
ATOM   6320  N ND2 . ASN B 1 371 ? 169.859 225.496 168.044 1.00 78.29  ? 392 ASN B ND2 1 
ATOM   6321  N N   . LYS B 1 372 ? 173.100 222.696 164.979 1.00 77.62  ? 393 LYS B N   1 
ATOM   6322  C CA  . LYS B 1 372 ? 172.652 222.264 163.666 1.00 77.62  ? 393 LYS B CA  1 
ATOM   6323  C C   . LYS B 1 372 ? 172.609 220.741 163.649 1.00 77.62  ? 393 LYS B C   1 
ATOM   6324  O O   . LYS B 1 372 ? 173.435 220.091 164.308 1.00 77.62  ? 393 LYS B O   1 
ATOM   6325  C CB  . LYS B 1 372 ? 173.563 222.778 162.539 1.00 77.62  ? 393 LYS B CB  1 
ATOM   6326  C CG  . LYS B 1 372 ? 175.046 222.495 162.715 1.00 77.62  ? 393 LYS B CG  1 
ATOM   6327  C CD  . LYS B 1 372 ? 175.858 223.206 161.642 1.00 77.62  ? 393 LYS B CD  1 
ATOM   6328  C CE  . LYS B 1 372 ? 177.352 223.093 161.898 1.00 77.62  ? 393 LYS B CE  1 
ATOM   6329  N NZ  . LYS B 1 372 ? 177.814 221.679 161.861 1.00 77.62  ? 393 LYS B NZ  1 
ATOM   6330  N N   . PRO B 1 373 ? 171.656 220.145 162.934 1.00 79.55  ? 394 PRO B N   1 
ATOM   6331  C CA  . PRO B 1 373 ? 171.607 218.682 162.854 1.00 79.55  ? 394 PRO B CA  1 
ATOM   6332  C C   . PRO B 1 373 ? 172.692 218.129 161.943 1.00 79.55  ? 394 PRO B C   1 
ATOM   6333  O O   . PRO B 1 373 ? 173.224 218.812 161.066 1.00 79.55  ? 394 PRO B O   1 
ATOM   6334  C CB  . PRO B 1 373 ? 170.212 218.403 162.285 1.00 79.55  ? 394 PRO B CB  1 
ATOM   6335  C CG  . PRO B 1 373 ? 169.881 219.627 161.512 1.00 79.55  ? 394 PRO B CG  1 
ATOM   6336  C CD  . PRO B 1 373 ? 170.495 220.768 162.272 1.00 79.55  ? 394 PRO B CD  1 
ATOM   6337  N N   . ILE B 1 374 ? 173.015 216.858 162.170 1.00 81.21  ? 395 ILE B N   1 
ATOM   6338  C CA  . ILE B 1 374 ? 173.972 216.119 161.356 1.00 81.21  ? 395 ILE B CA  1 
ATOM   6339  C C   . ILE B 1 374 ? 173.204 215.079 160.556 1.00 81.21  ? 395 ILE B C   1 
ATOM   6340  O O   . ILE B 1 374 ? 172.455 214.276 161.126 1.00 81.21  ? 395 ILE B O   1 
ATOM   6341  C CB  . ILE B 1 374 ? 175.062 215.458 162.218 1.00 81.21  ? 395 ILE B CB  1 
ATOM   6342  C CG1 . ILE B 1 374 ? 175.601 216.449 163.252 1.00 81.21  ? 395 ILE B CG1 1 
ATOM   6343  C CG2 . ILE B 1 374 ? 176.187 214.933 161.340 1.00 81.21  ? 395 ILE B CG2 1 
ATOM   6344  C CD1 . ILE B 1 374 ? 176.419 215.801 164.345 1.00 81.21  ? 395 ILE B CD1 1 
ATOM   6345  N N   . VAL B 1 375 ? 173.390 215.090 159.241 1.00 81.14  ? 396 VAL B N   1 
ATOM   6346  C CA  . VAL B 1 375 ? 172.643 214.228 158.335 1.00 81.14  ? 396 VAL B CA  1 
ATOM   6347  C C   . VAL B 1 375 ? 173.578 213.127 157.842 1.00 81.14  ? 396 VAL B C   1 
ATOM   6348  O O   . VAL B 1 375 ? 174.803 213.296 157.794 1.00 81.14  ? 396 VAL B O   1 
ATOM   6349  C CB  . VAL B 1 375 ? 172.031 215.063 157.179 1.00 81.14  ? 396 VAL B CB  1 
ATOM   6350  C CG1 . VAL B 1 375 ? 173.107 215.623 156.246 1.00 81.14  ? 396 VAL B CG1 1 
ATOM   6351  C CG2 . VAL B 1 375 ? 170.937 214.301 156.416 1.00 81.14  ? 396 VAL B CG2 1 
ATOM   6352  N N   . GLN B 1 376 ? 172.995 211.968 157.536 1.00 77.68  ? 397 GLN B N   1 
ATOM   6353  C CA  . GLN B 1 376 ? 173.760 210.841 157.018 1.00 77.68  ? 397 GLN B CA  1 
ATOM   6354  C C   . GLN B 1 376 ? 174.269 211.133 155.613 1.00 77.68  ? 397 GLN B C   1 
ATOM   6355  O O   . GLN B 1 376 ? 173.510 211.568 154.743 1.00 77.68  ? 397 GLN B O   1 
ATOM   6356  C CB  . GLN B 1 376 ? 172.895 209.582 156.998 1.00 77.68  ? 397 GLN B CB  1 
ATOM   6357  C CG  . GLN B 1 376 ? 172.808 208.845 158.316 1.00 77.68  ? 397 GLN B CG  1 
ATOM   6358  C CD  . GLN B 1 376 ? 174.074 208.081 158.639 1.00 77.68  ? 397 GLN B CD  1 
ATOM   6359  O OE1 . GLN B 1 376 ? 174.817 208.449 159.544 1.00 77.68  ? 397 GLN B OE1 1 
ATOM   6360  N NE2 . GLN B 1 376 ? 174.326 207.009 157.896 1.00 77.68  ? 397 GLN B NE2 1 
ATOM   6361  N N   . SER B 1 377 ? 175.558 210.893 155.394 1.00 78.99  ? 398 SER B N   1 
ATOM   6362  C CA  . SER B 1 377 ? 176.095 210.909 154.043 1.00 78.99  ? 398 SER B CA  1 
ATOM   6363  C C   . SER B 1 377 ? 175.650 209.657 153.296 1.00 78.99  ? 398 SER B C   1 
ATOM   6364  O O   . SER B 1 377 ? 175.504 208.580 153.878 1.00 78.99  ? 398 SER B O   1 
ATOM   6365  C CB  . SER B 1 377 ? 177.620 210.994 154.069 1.00 78.99  ? 398 SER B CB  1 
ATOM   6366  O OG  . SER B 1 377 ? 178.154 210.949 152.757 1.00 78.99  ? 398 SER B OG  1 
ATOM   6367  N N   . THR B 1 378 ? 175.417 209.810 151.992 1.00 69.45  ? 399 THR B N   1 
ATOM   6368  C CA  . THR B 1 378 ? 174.960 208.680 151.192 1.00 69.45  ? 399 THR B CA  1 
ATOM   6369  C C   . THR B 1 378 ? 176.077 207.693 150.881 1.00 69.45  ? 399 THR B C   1 
ATOM   6370  O O   . THR B 1 378 ? 175.791 206.534 150.564 1.00 69.45  ? 399 THR B O   1 
ATOM   6371  C CB  . THR B 1 378 ? 174.331 209.175 149.890 1.00 69.45  ? 399 THR B CB  1 
ATOM   6372  O OG1 . THR B 1 378 ? 175.348 209.732 149.049 1.00 69.45  ? 399 THR B OG1 1 
ATOM   6373  C CG2 . THR B 1 378 ? 173.280 210.236 150.178 1.00 69.45  ? 399 THR B CG2 1 
ATOM   6374  N N   . SER B 1 379 ? 177.338 208.121 150.964 1.00 81.09  ? 400 SER B N   1 
ATOM   6375  C CA  . SER B 1 379 ? 178.453 207.254 150.603 1.00 81.09  ? 400 SER B CA  1 
ATOM   6376  C C   . SER B 1 379 ? 178.821 206.260 151.697 1.00 81.09  ? 400 SER B C   1 
ATOM   6377  O O   . SER B 1 379 ? 179.499 205.269 151.406 1.00 81.09  ? 400 SER B O   1 
ATOM   6378  C CB  . SER B 1 379 ? 179.677 208.100 150.247 1.00 81.09  ? 400 SER B CB  1 
ATOM   6379  O OG  . SER B 1 379 ? 180.135 208.832 151.370 1.00 81.09  ? 400 SER B OG  1 
ATOM   6380  N N   . THR B 1 380 ? 178.398 206.494 152.937 1.00 76.56  ? 401 THR B N   1 
ATOM   6381  C CA  . THR B 1 380 ? 178.757 205.637 154.058 1.00 76.56  ? 401 THR B CA  1 
ATOM   6382  C C   . THR B 1 380 ? 177.527 205.368 154.914 1.00 76.56  ? 401 THR B C   1 
ATOM   6383  O O   . THR B 1 380 ? 176.485 206.009 154.767 1.00 76.56  ? 401 THR B O   1 
ATOM   6384  C CB  . THR B 1 380 ? 179.869 206.264 154.911 1.00 76.56  ? 401 THR B CB  1 
ATOM   6385  O OG1 . THR B 1 380 ? 180.239 205.357 155.957 1.00 76.56  ? 401 THR B OG1 1 
ATOM   6386  C CG2 . THR B 1 380 ? 179.396 207.573 155.522 1.00 76.56  ? 401 THR B CG2 1 
ATOM   6387  N N   . VAL B 1 381 ? 177.655 204.396 155.812 1.00 65.14  ? 402 VAL B N   1 
ATOM   6388  C CA  . VAL B 1 381 ? 176.581 204.007 156.716 1.00 65.14  ? 402 VAL B CA  1 
ATOM   6389  C C   . VAL B 1 381 ? 176.881 204.432 158.150 1.00 65.14  ? 402 VAL B C   1 
ATOM   6390  O O   . VAL B 1 381 ? 176.018 204.979 158.838 1.00 65.14  ? 402 VAL B O   1 
ATOM   6391  C CB  . VAL B 1 381 ? 176.310 202.488 156.634 1.00 65.14  ? 402 VAL B CB  1 
ATOM   6392  C CG1 . VAL B 1 381 ? 174.999 202.151 157.317 1.00 65.14  ? 402 VAL B CG1 1 
ATOM   6393  C CG2 . VAL B 1 381 ? 176.298 202.024 155.187 1.00 65.14  ? 402 VAL B CG2 1 
ATOM   6394  N N   . ILE B 1 382 ? 178.103 204.188 158.616 1.00 55.81  ? 403 ILE B N   1 
ATOM   6395  C CA  . ILE B 1 382 ? 178.526 204.548 159.964 1.00 55.81  ? 403 ILE B CA  1 
ATOM   6396  C C   . ILE B 1 382 ? 179.247 205.887 159.895 1.00 55.81  ? 403 ILE B C   1 
ATOM   6397  O O   . ILE B 1 382 ? 180.158 206.069 159.079 1.00 55.81  ? 403 ILE B O   1 
ATOM   6398  C CB  . ILE B 1 382 ? 179.425 203.460 160.575 1.00 55.81  ? 403 ILE B CB  1 
ATOM   6399  C CG1 . ILE B 1 382 ? 178.703 202.113 160.554 1.00 55.81  ? 403 ILE B CG1 1 
ATOM   6400  C CG2 . ILE B 1 382 ? 179.818 203.823 161.998 1.00 55.81  ? 403 ILE B CG2 1 
ATOM   6401  C CD1 . ILE B 1 382 ? 177.433 202.091 161.372 1.00 55.81  ? 403 ILE B CD1 1 
ATOM   6402  N N   . THR B 1 383 ? 178.843 206.821 160.750 1.00 52.14  ? 404 THR B N   1 
ATOM   6403  C CA  . THR B 1 383 ? 179.262 208.211 160.650 1.00 52.14  ? 404 THR B CA  1 
ATOM   6404  C C   . THR B 1 383 ? 180.423 208.506 161.593 1.00 52.14  ? 404 THR B C   1 
ATOM   6405  O O   . THR B 1 383 ? 180.341 208.236 162.799 1.00 52.14  ? 404 THR B O   1 
ATOM   6406  C CB  . THR B 1 383 ? 178.090 209.146 160.952 1.00 52.14  ? 404 THR B CB  1 
ATOM   6407  O OG1 . THR B 1 383 ? 177.009 208.850 160.063 1.00 52.14  ? 404 THR B OG1 1 
ATOM   6408  C CG2 . THR B 1 383 ? 178.498 210.595 160.763 1.00 52.14  ? 404 THR B CG2 1 
ATOM   6409  N N   . MET B 1 384 ? 181.506 209.027 161.018 1.00 50.06  ? 405 MET B N   1 
ATOM   6410  C CA  . MET B 1 384 ? 182.573 209.678 161.767 1.00 50.06  ? 405 MET B CA  1 
ATOM   6411  C C   . MET B 1 384 ? 182.098 210.945 162.463 1.00 50.06  ? 405 MET B C   1 
ATOM   6412  O O   . MET B 1 384 ? 181.438 211.791 161.853 1.00 50.06  ? 405 MET B O   1 
ATOM   6413  C CB  . MET B 1 384 ? 183.721 210.019 160.820 1.00 50.06  ? 405 MET B CB  1 
ATOM   6414  C CG  . MET B 1 384 ? 184.904 210.704 161.477 1.00 50.06  ? 405 MET B CG  1 
ATOM   6415  S SD  . MET B 1 384 ? 185.775 209.780 162.734 1.00 50.06  ? 405 MET B SD  1 
ATOM   6416  C CE  . MET B 1 384 ? 186.642 208.576 161.750 1.00 50.06  ? 405 MET B CE  1 
ATOM   6417  N N   . ILE B 1 385 ? 182.457 211.083 163.738 1.00 52.66  ? 406 ILE B N   1 
ATOM   6418  C CA  . ILE B 1 385 ? 182.371 212.350 164.454 1.00 52.66  ? 406 ILE B CA  1 
ATOM   6419  C C   . ILE B 1 385 ? 183.691 212.549 165.193 1.00 52.66  ? 406 ILE B C   1 
ATOM   6420  O O   . ILE B 1 385 ? 184.112 211.679 165.969 1.00 52.66  ? 406 ILE B O   1 
ATOM   6421  C CB  . ILE B 1 385 ? 181.177 212.389 165.425 1.00 52.66  ? 406 ILE B CB  1 
ATOM   6422  C CG1 . ILE B 1 385 ? 179.866 212.582 164.661 1.00 52.66  ? 406 ILE B CG1 1 
ATOM   6423  C CG2 . ILE B 1 385 ? 181.340 213.495 166.449 1.00 52.66  ? 406 ILE B CG2 1 
ATOM   6424  C CD1 . ILE B 1 385 ? 178.637 212.501 165.533 1.00 52.66  ? 406 ILE B CD1 1 
ATOM   6425  N N   . ASP B 1 386 ? 184.347 213.680 164.940 1.00 64.24  ? 407 ASP B N   1 
ATOM   6426  C CA  . ASP B 1 386 ? 185.595 214.037 165.603 1.00 64.24  ? 407 ASP B CA  1 
ATOM   6427  C C   . ASP B 1 386 ? 185.516 215.505 166.008 1.00 64.24  ? 407 ASP B C   1 
ATOM   6428  O O   . ASP B 1 386 ? 184.448 216.124 165.972 1.00 64.24  ? 407 ASP B O   1 
ATOM   6429  C CB  . ASP B 1 386 ? 186.802 213.763 164.696 1.00 64.24  ? 407 ASP B CB  1 
ATOM   6430  C CG  . ASP B 1 386 ? 186.664 214.406 163.329 1.00 64.24  ? 407 ASP B CG  1 
ATOM   6431  O OD1 . ASP B 1 386 ? 185.538 214.796 162.959 1.00 64.24  ? 407 ASP B OD1 1 
ATOM   6432  O OD2 . ASP B 1 386 ? 187.691 214.544 162.633 1.00 64.24  ? 407 ASP B OD2 1 
ATOM   6433  N N   . ASN B 1 387 ? 186.659 216.069 166.399 1.00 67.85  ? 408 ASN B N   1 
ATOM   6434  C CA  . ASN B 1 387 ? 186.722 217.482 166.751 1.00 67.85  ? 408 ASN B CA  1 
ATOM   6435  C C   . ASN B 1 387 ? 186.759 218.412 165.542 1.00 67.85  ? 408 ASN B C   1 
ATOM   6436  O O   . ASN B 1 387 ? 186.601 219.625 165.712 1.00 67.85  ? 408 ASN B O   1 
ATOM   6437  C CB  . ASN B 1 387 ? 187.915 217.735 167.692 1.00 67.85  ? 408 ASN B CB  1 
ATOM   6438  C CG  . ASN B 1 387 ? 189.280 217.379 167.080 1.00 67.85  ? 408 ASN B CG  1 
ATOM   6439  O OD1 . ASN B 1 387 ? 189.407 217.030 165.904 1.00 67.85  ? 408 ASN B OD1 1 
ATOM   6440  N ND2 . ASN B 1 387 ? 190.317 217.472 167.906 1.00 67.85  ? 408 ASN B ND2 1 
ATOM   6441  N N   . SER B 1 388 ? 186.968 217.876 164.336 1.00 68.24  ? 409 SER B N   1 
ATOM   6442  C CA  . SER B 1 388 ? 186.921 218.708 163.139 1.00 68.24  ? 409 SER B CA  1 
ATOM   6443  C C   . SER B 1 388 ? 185.494 219.123 162.802 1.00 68.24  ? 409 SER B C   1 
ATOM   6444  O O   . SER B 1 388 ? 185.281 220.197 162.230 1.00 68.24  ? 409 SER B O   1 
ATOM   6445  C CB  . SER B 1 388 ? 187.556 217.967 161.962 1.00 68.24  ? 409 SER B CB  1 
ATOM   6446  O OG  . SER B 1 388 ? 188.930 217.714 162.205 1.00 68.24  ? 409 SER B OG  1 
ATOM   6447  N N   . LYS B 1 389 ? 184.509 218.292 163.147 1.00 70.46  ? 410 LYS B N   1 
ATOM   6448  C CA  . LYS B 1 389 ? 183.114 218.649 162.908 1.00 70.46  ? 410 LYS B CA  1 
ATOM   6449  C C   . LYS B 1 389 ? 182.622 219.649 163.948 1.00 70.46  ? 410 LYS B C   1 
ATOM   6450  O O   . LYS B 1 389 ? 182.265 220.785 163.614 1.00 70.46  ? 410 LYS B O   1 
ATOM   6451  C CB  . LYS B 1 389 ? 182.241 217.391 162.919 1.00 70.46  ? 410 LYS B CB  1 
ATOM   6452  C CG  . LYS B 1 389 ? 182.674 216.318 161.934 1.00 70.46  ? 410 LYS B CG  1 
ATOM   6453  C CD  . LYS B 1 389 ? 182.349 216.702 160.502 1.00 70.46  ? 410 LYS B CD  1 
ATOM   6454  C CE  . LYS B 1 389 ? 182.651 215.555 159.551 1.00 70.46  ? 410 LYS B CE  1 
ATOM   6455  N NZ  . LYS B 1 389 ? 182.345 215.900 158.136 1.00 70.46  ? 410 LYS B NZ  1 
ATOM   6456  N N   . CYS B 1 390 ? 182.617 219.243 165.224 1.00 80.97  ? 411 CYS B N   1 
ATOM   6457  C CA  . CYS B 1 390 ? 182.149 220.065 166.332 1.00 80.97  ? 411 CYS B CA  1 
ATOM   6458  C C   . CYS B 1 390 ? 182.681 219.487 167.632 1.00 80.97  ? 411 CYS B C   1 
ATOM   6459  O O   . CYS B 1 390 ? 182.785 218.258 167.745 1.00 80.97  ? 411 CYS B O   1 
ATOM   6460  C CB  . CYS B 1 390 ? 180.618 220.138 166.365 1.00 80.97  ? 411 CYS B CB  1 
ATOM   6461  S SG  . CYS B 1 390 ? 179.779 218.539 166.366 1.00 80.97  ? 411 CYS B SG  1 
ATOM   6462  N N   . PRO B 1 391 ? 183.045 220.325 168.619 1.00 67.92  ? 412 PRO B N   1 
ATOM   6463  C CA  . PRO B 1 391 ? 183.595 219.800 169.879 1.00 67.92  ? 412 PRO B CA  1 
ATOM   6464  C C   . PRO B 1 391 ? 182.586 219.052 170.739 1.00 67.92  ? 412 PRO B C   1 
ATOM   6465  O O   . PRO B 1 391 ? 182.847 217.923 171.166 1.00 67.92  ? 412 PRO B O   1 
ATOM   6466  C CB  . PRO B 1 391 ? 184.094 221.064 170.593 1.00 67.92  ? 412 PRO B CB  1 
ATOM   6467  C CG  . PRO B 1 391 ? 184.252 222.084 169.508 1.00 67.92  ? 412 PRO B CG  1 
ATOM   6468  C CD  . PRO B 1 391 ? 183.139 221.792 168.555 1.00 67.92  ? 412 PRO B CD  1 
ATOM   6469  N N   . VAL B 1 392 ? 181.434 219.663 171.000 1.00 67.61  ? 413 VAL B N   1 
ATOM   6470  C CA  . VAL B 1 392 ? 180.427 219.097 171.891 1.00 67.61  ? 413 VAL B CA  1 
ATOM   6471  C C   . VAL B 1 392 ? 179.300 218.535 171.038 1.00 67.61  ? 413 VAL B C   1 
ATOM   6472  O O   . VAL B 1 392 ? 178.706 219.254 170.225 1.00 67.61  ? 413 VAL B O   1 
ATOM   6473  C CB  . VAL B 1 392 ? 179.903 220.146 172.881 1.00 67.61  ? 413 VAL B CB  1 
ATOM   6474  C CG1 . VAL B 1 392 ? 179.092 219.477 173.968 1.00 67.61  ? 413 VAL B CG1 1 
ATOM   6475  C CG2 . VAL B 1 392 ? 181.060 220.933 173.475 1.00 67.61  ? 413 VAL B CG2 1 
ATOM   6476  N N   . VAL B 1 393 ? 179.003 217.250 171.222 1.00 59.58  ? 414 VAL B N   1 
ATOM   6477  C CA  . VAL B 1 393 ? 178.139 216.493 170.322 1.00 59.58  ? 414 VAL B CA  1 
ATOM   6478  C C   . VAL B 1 393 ? 176.931 215.988 171.103 1.00 59.58  ? 414 VAL B C   1 
ATOM   6479  O O   . VAL B 1 393 ? 177.076 215.459 172.210 1.00 59.58  ? 414 VAL B O   1 
ATOM   6480  C CB  . VAL B 1 393 ? 178.899 215.319 169.675 1.00 59.58  ? 414 VAL B CB  1 
ATOM   6481  C CG1 . VAL B 1 393 ? 178.093 214.718 168.546 1.00 59.58  ? 414 VAL B CG1 1 
ATOM   6482  C CG2 . VAL B 1 393 ? 180.268 215.759 169.180 1.00 59.58  ? 414 VAL B CG2 1 
ATOM   6483  N N   . GLU B 1 394 ? 175.741 216.172 170.533 1.00 72.56  ? 415 GLU B N   1 
ATOM   6484  C CA  . GLU B 1 394 ? 174.511 215.572 171.040 1.00 72.56  ? 415 GLU B CA  1 
ATOM   6485  C C   . GLU B 1 394 ? 174.303 214.240 170.329 1.00 72.56  ? 415 GLU B C   1 
ATOM   6486  O O   . GLU B 1 394 ? 174.058 214.205 169.117 1.00 72.56  ? 415 GLU B O   1 
ATOM   6487  C CB  . GLU B 1 394 ? 173.329 216.520 170.823 1.00 72.56  ? 415 GLU B CB  1 
ATOM   6488  C CG  . GLU B 1 394 ? 171.916 215.913 170.903 1.00 72.56  ? 415 GLU B CG  1 
ATOM   6489  C CD  . GLU B 1 394 ? 171.508 215.435 172.287 1.00 72.56  ? 415 GLU B CD  1 
ATOM   6490  O OE1 . GLU B 1 394 ? 172.101 215.866 173.290 1.00 72.56  ? 415 GLU B OE1 1 
ATOM   6491  O OE2 . GLU B 1 394 ? 170.553 214.641 172.375 1.00 72.56  ? 415 GLU B OE2 1 
ATOM   6492  N N   . VAL B 1 395 ? 174.441 213.144 171.075 1.00 63.79  ? 416 VAL B N   1 
ATOM   6493  C CA  . VAL B 1 395 ? 174.186 211.797 170.574 1.00 63.79  ? 416 VAL B CA  1 
ATOM   6494  C C   . VAL B 1 395 ? 173.250 211.105 171.553 1.00 63.79  ? 416 VAL B C   1 
ATOM   6495  O O   . VAL B 1 395 ? 173.541 211.038 172.753 1.00 63.79  ? 416 VAL B O   1 
ATOM   6496  C CB  . VAL B 1 395 ? 175.488 210.989 170.396 1.00 63.79  ? 416 VAL B CB  1 
ATOM   6497  C CG1 . VAL B 1 395 ? 175.182 209.526 170.150 1.00 63.79  ? 416 VAL B CG1 1 
ATOM   6498  C CG2 . VAL B 1 395 ? 176.298 211.532 169.237 1.00 63.79  ? 416 VAL B CG2 1 
ATOM   6499  N N   . GLY B 1 396 ? 172.131 210.589 171.044 1.00 68.00  ? 417 GLY B N   1 
ATOM   6500  C CA  . GLY B 1 396 ? 171.109 210.022 171.900 1.00 68.00  ? 417 GLY B CA  1 
ATOM   6501  C C   . GLY B 1 396 ? 170.406 211.114 172.673 1.00 68.00  ? 417 GLY B C   1 
ATOM   6502  O O   . GLY B 1 396 ? 169.700 211.935 172.086 1.00 68.00  ? 417 GLY B O   1 
ATOM   6503  N N   . LYS B 1 397 ? 170.597 211.126 173.993 1.00 73.34  ? 418 LYS B N   1 
ATOM   6504  C CA  . LYS B 1 397 ? 170.205 212.234 174.856 1.00 73.34  ? 418 LYS B CA  1 
ATOM   6505  C C   . LYS B 1 397 ? 171.418 212.889 175.508 1.00 73.34  ? 418 LYS B C   1 
ATOM   6506  O O   . LYS B 1 397 ? 171.263 213.688 176.437 1.00 73.34  ? 418 LYS B O   1 
ATOM   6507  C CB  . LYS B 1 397 ? 169.231 211.757 175.940 1.00 73.34  ? 418 LYS B CB  1 
ATOM   6508  C CG  . LYS B 1 397 ? 167.871 211.164 175.512 1.00 73.34  ? 418 LYS B CG  1 
ATOM   6509  C CD  . LYS B 1 397 ? 166.854 212.195 174.990 1.00 73.34  ? 418 LYS B CD  1 
ATOM   6510  C CE  . LYS B 1 397 ? 166.813 212.351 173.477 1.00 73.34  ? 418 LYS B CE  1 
ATOM   6511  N NZ  . LYS B 1 397 ? 165.739 213.285 173.043 1.00 73.34  ? 418 LYS B NZ  1 
ATOM   6512  N N   . GLN B 1 398 ? 172.622 212.573 175.037 1.00 67.90  ? 419 GLN B N   1 
ATOM   6513  C CA  . GLN B 1 398 ? 173.850 212.838 175.776 1.00 67.90  ? 419 GLN B CA  1 
ATOM   6514  C C   . GLN B 1 398 ? 174.704 213.900 175.097 1.00 67.90  ? 419 GLN B C   1 
ATOM   6515  O O   . GLN B 1 398 ? 174.973 213.816 173.892 1.00 67.90  ? 419 GLN B O   1 
ATOM   6516  C CB  . GLN B 1 398 ? 174.670 211.556 175.937 1.00 67.90  ? 419 GLN B CB  1 
ATOM   6517  C CG  . GLN B 1 398 ? 173.866 210.334 176.338 1.00 67.90  ? 419 GLN B CG  1 
ATOM   6518  C CD  . GLN B 1 398 ? 173.599 210.278 177.829 1.00 67.90  ? 419 GLN B CD  1 
ATOM   6519  O OE1 . GLN B 1 398 ? 174.168 211.048 178.603 1.00 67.90  ? 419 GLN B OE1 1 
ATOM   6520  N NE2 . GLN B 1 398 ? 172.740 209.354 178.241 1.00 67.90  ? 419 GLN B NE2 1 
ATOM   6521  N N   . MET B 1 399 ? 175.110 214.901 175.879 1.00 73.58  ? 420 MET B N   1 
ATOM   6522  C CA  . MET B 1 399 ? 176.310 215.672 175.582 1.00 73.58  ? 420 MET B CA  1 
ATOM   6523  C C   . MET B 1 399 ? 177.544 214.792 175.729 1.00 73.58  ? 420 MET B C   1 
ATOM   6524  O O   . MET B 1 399 ? 177.726 214.130 176.755 1.00 73.58  ? 420 MET B O   1 
ATOM   6525  C CB  . MET B 1 399 ? 176.435 216.861 176.534 1.00 73.58  ? 420 MET B CB  1 
ATOM   6526  C CG  . MET B 1 399 ? 175.441 218.007 176.433 1.00 73.58  ? 420 MET B CG  1 
ATOM   6527  S SD  . MET B 1 399 ? 175.556 218.895 174.871 1.00 73.58  ? 420 MET B SD  1 
ATOM   6528  C CE  . MET B 1 399 ? 174.139 218.295 173.985 1.00 73.58  ? 420 MET B CE  1 
ATOM   6529  N N   . ILE B 1 400 ? 178.400 214.794 174.711 1.00 64.01  ? 421 ILE B N   1 
ATOM   6530  C CA  . ILE B 1 400 ? 179.698 214.135 174.773 1.00 64.01  ? 421 ILE B CA  1 
ATOM   6531  C C   . ILE B 1 400 ? 180.744 215.071 174.187 1.00 64.01  ? 421 ILE B C   1 
ATOM   6532  O O   . ILE B 1 400 ? 180.432 215.966 173.395 1.00 64.01  ? 421 ILE B O   1 
ATOM   6533  C CB  . ILE B 1 400 ? 179.705 212.776 174.033 1.00 64.01  ? 421 ILE B CB  1 
ATOM   6534  C CG1 . ILE B 1 400 ? 179.150 212.940 172.619 1.00 64.01  ? 421 ILE B CG1 1 
ATOM   6535  C CG2 . ILE B 1 400 ? 178.946 211.704 174.810 1.00 64.01  ? 421 ILE B CG2 1 
ATOM   6536  C CD1 . ILE B 1 400 ? 179.195 211.690 171.797 1.00 64.01  ? 421 ILE B CD1 1 
ATOM   6537  N N   . SER B 1 401 ? 181.993 214.867 174.590 1.00 56.24  ? 422 SER B N   1 
ATOM   6538  C CA  . SER B 1 401 ? 183.119 215.612 174.049 1.00 56.24  ? 422 SER B CA  1 
ATOM   6539  C C   . SER B 1 401 ? 184.066 214.662 173.330 1.00 56.24  ? 422 SER B C   1 
ATOM   6540  O O   . SER B 1 401 ? 184.203 213.490 173.692 1.00 56.24  ? 422 SER B O   1 
ATOM   6541  C CB  . SER B 1 401 ? 183.867 216.372 175.149 1.00 56.24  ? 422 SER B CB  1 
ATOM   6542  O OG  . SER B 1 401 ? 183.052 217.382 175.716 1.00 56.24  ? 422 SER B OG  1 
ATOM   6543  N N   . VAL B 1 402 ? 184.724 215.186 172.300 1.00 50.73  ? 423 VAL B N   1 
ATOM   6544  C CA  . VAL B 1 402 ? 185.574 214.374 171.438 1.00 50.73  ? 423 VAL B CA  1 
ATOM   6545  C C   . VAL B 1 402 ? 186.995 214.918 171.454 1.00 50.73  ? 423 VAL B C   1 
ATOM   6546  O O   . VAL B 1 402 ? 187.290 215.903 172.140 1.00 50.73  ? 423 VAL B O   1 
ATOM   6547  C CB  . VAL B 1 402 ? 185.021 214.329 170.003 1.00 50.73  ? 423 VAL B CB  1 
ATOM   6548  C CG1 . VAL B 1 402 ? 183.722 213.551 169.959 1.00 50.73  ? 423 VAL B CG1 1 
ATOM   6549  C CG2 . VAL B 1 402 ? 184.805 215.737 169.490 1.00 50.73  ? 423 VAL B CG2 1 
ATOM   6550  N N   . GLY B 1 403 ? 187.879 214.274 170.705 1.00 63.26  ? 424 GLY B N   1 
ATOM   6551  C CA  . GLY B 1 403 ? 189.258 214.709 170.646 1.00 63.26  ? 424 GLY B CA  1 
ATOM   6552  C C   . GLY B 1 403 ? 190.029 213.918 169.616 1.00 63.26  ? 424 GLY B C   1 
ATOM   6553  O O   . GLY B 1 403 ? 189.451 213.172 168.821 1.00 63.26  ? 424 GLY B O   1 
ATOM   6554  N N   . SER B 1 404 ? 191.347 214.099 169.655 1.00 79.49  ? 425 SER B N   1 
ATOM   6555  C CA  . SER B 1 404 ? 192.360 213.458 168.786 1.00 79.49  ? 425 SER B CA  1 
ATOM   6556  C C   . SER B 1 404 ? 192.034 213.812 167.331 1.00 79.49  ? 425 SER B C   1 
ATOM   6557  O O   . SER B 1 404 ? 191.619 214.947 167.049 1.00 79.49  ? 425 SER B O   1 
ATOM   6558  C CB  . SER B 1 404 ? 192.446 211.970 169.084 1.00 79.49  ? 425 SER B CB  1 
ATOM   6559  O OG  . SER B 1 404 ? 193.382 211.332 168.232 1.00 79.49  ? 425 SER B OG  1 
ATOM   6560  N N   . TYR B 1 405 ? 192.201 212.883 166.399 1.00 98.54  ? 426 TYR B N   1 
ATOM   6561  C CA  . TYR B 1 405 ? 191.956 213.146 164.987 1.00 98.54  ? 426 TYR B CA  1 
ATOM   6562  C C   . TYR B 1 405 ? 191.491 211.846 164.336 1.00 98.54  ? 426 TYR B C   1 
ATOM   6563  O O   . TYR B 1 405 ? 191.107 210.897 165.027 1.00 98.54  ? 426 TYR B O   1 
ATOM   6564  C CB  . TYR B 1 405 ? 193.206 213.775 164.341 1.00 98.54  ? 426 TYR B CB  1 
ATOM   6565  C CG  . TYR B 1 405 ? 194.451 212.908 164.340 1.00 98.54  ? 426 TYR B CG  1 
ATOM   6566  C CD1 . TYR B 1 405 ? 195.345 212.945 165.407 1.00 98.54  ? 426 TYR B CD1 1 
ATOM   6567  C CD2 . TYR B 1 405 ? 194.758 212.091 163.258 1.00 98.54  ? 426 TYR B CD2 1 
ATOM   6568  C CE1 . TYR B 1 405 ? 196.490 212.166 165.410 1.00 98.54  ? 426 TYR B CE1 1 
ATOM   6569  C CE2 . TYR B 1 405 ? 195.900 211.307 163.251 1.00 98.54  ? 426 TYR B CE2 1 
ATOM   6570  C CZ  . TYR B 1 405 ? 196.762 211.351 164.329 1.00 98.54  ? 426 TYR B CZ  1 
ATOM   6571  O OH  . TYR B 1 405 ? 197.900 210.577 164.325 1.00 98.54  ? 426 TYR B OH  1 
ATOM   6572  N N   . LEU B 1 406 ? 191.511 211.810 163.002 1.00 95.14  ? 427 LEU B N   1 
ATOM   6573  C CA  . LEU B 1 406 ? 190.960 210.677 162.262 1.00 95.14  ? 427 LEU B CA  1 
ATOM   6574  C C   . LEU B 1 406 ? 191.842 209.440 162.391 1.00 95.14  ? 427 LEU B C   1 
ATOM   6575  O O   . LEU B 1 406 ? 191.389 208.383 162.845 1.00 95.14  ? 427 LEU B O   1 
ATOM   6576  C CB  . LEU B 1 406 ? 190.787 211.061 160.792 1.00 95.14  ? 427 LEU B CB  1 
ATOM   6577  C CG  . LEU B 1 406 ? 189.818 212.207 160.504 1.00 95.14  ? 427 LEU B CG  1 
ATOM   6578  C CD1 . LEU B 1 406 ? 189.879 212.614 159.042 1.00 95.14  ? 427 LEU B CD1 1 
ATOM   6579  C CD2 . LEU B 1 406 ? 188.412 211.798 160.881 1.00 95.14  ? 427 LEU B CD2 1 
ATOM   6580  N N   . GLY B 1 407 ? 193.105 209.554 161.993 1.00 99.80  ? 428 GLY B N   1 
ATOM   6581  C CA  . GLY B 1 407 ? 194.003 208.417 161.983 1.00 99.80  ? 428 GLY B CA  1 
ATOM   6582  C C   . GLY B 1 407 ? 194.134 207.816 160.600 1.00 99.80  ? 428 GLY B C   1 
ATOM   6583  O O   . GLY B 1 407 ? 193.194 207.175 160.115 1.00 99.80  ? 428 GLY B O   1 
ATOM   6584  N N   . GLN B 1 408 ? 195.301 208.028 159.973 1.00 104.19 ? 429 GLN B N   1 
ATOM   6585  C CA  . GLN B 1 408 ? 195.628 207.633 158.601 1.00 104.19 ? 429 GLN B CA  1 
ATOM   6586  C C   . GLN B 1 408 ? 194.617 208.198 157.609 1.00 104.19 ? 429 GLN B C   1 
ATOM   6587  O O   . GLN B 1 408 ? 194.742 209.348 157.176 1.00 104.19 ? 429 GLN B O   1 
ATOM   6588  C CB  . GLN B 1 408 ? 195.736 206.107 158.470 1.00 104.19 ? 429 GLN B CB  1 
ATOM   6589  C CG  . GLN B 1 408 ? 196.480 205.638 157.226 1.00 104.19 ? 429 GLN B CG  1 
ATOM   6590  C CD  . GLN B 1 408 ? 197.949 206.011 157.251 1.00 104.19 ? 429 GLN B CD  1 
ATOM   6591  O OE1 . GLN B 1 408 ? 198.627 205.842 158.264 1.00 104.19 ? 429 GLN B OE1 1 
ATOM   6592  N NE2 . GLN B 1 408 ? 198.447 206.525 156.133 1.00 104.19 ? 429 GLN B NE2 1 
ATOM   6593  N N   . VAL B 1 409 ? 193.614 207.402 157.245 1.00 100.62 ? 430 VAL B N   1 
ATOM   6594  C CA  . VAL B 1 409 ? 192.562 207.836 156.338 1.00 100.62 ? 430 VAL B CA  1 
ATOM   6595  C C   . VAL B 1 409 ? 191.226 207.735 157.058 1.00 100.62 ? 430 VAL B C   1 
ATOM   6596  O O   . VAL B 1 409 ? 191.052 206.940 157.987 1.00 100.62 ? 430 VAL B O   1 
ATOM   6597  C CB  . VAL B 1 409 ? 192.542 207.019 155.026 1.00 100.62 ? 430 VAL B CB  1 
ATOM   6598  C CG1 . VAL B 1 409 ? 193.798 207.288 154.214 1.00 100.62 ? 430 VAL B CG1 1 
ATOM   6599  C CG2 . VAL B 1 409 ? 192.402 205.532 155.317 1.00 100.62 ? 430 VAL B CG2 1 
ATOM   6600  N N   . SER B 1 410 ? 190.289 208.566 156.637 1.00 103.27 ? 431 SER B N   1 
ATOM   6601  C CA  . SER B 1 410 ? 188.970 208.562 157.250 1.00 103.27 ? 431 SER B CA  1 
ATOM   6602  C C   . SER B 1 410 ? 188.146 207.403 156.700 1.00 103.27 ? 431 SER B C   1 
ATOM   6603  O O   . SER B 1 410 ? 188.137 207.179 155.486 1.00 103.27 ? 431 SER B O   1 
ATOM   6604  C CB  . SER B 1 410 ? 188.254 209.884 157.001 1.00 103.27 ? 431 SER B CB  1 
ATOM   6605  O OG  . SER B 1 410 ? 187.992 210.075 155.623 1.00 103.27 ? 431 SER B OG  1 
ATOM   6606  N N   . PRO B 1 411 ? 187.457 206.642 157.554 1.00 92.09  ? 432 PRO B N   1 
ATOM   6607  C CA  . PRO B 1 411 ? 186.561 205.591 157.053 1.00 92.09  ? 432 PRO B CA  1 
ATOM   6608  C C   . PRO B 1 411 ? 185.183 206.085 156.627 1.00 92.09  ? 432 PRO B C   1 
ATOM   6609  O O   . PRO B 1 411 ? 184.269 205.274 156.451 1.00 92.09  ? 432 PRO B O   1 
ATOM   6610  C CB  . PRO B 1 411 ? 186.460 204.626 158.240 1.00 92.09  ? 432 PRO B CB  1 
ATOM   6611  C CG  . PRO B 1 411 ? 186.749 205.462 159.430 1.00 92.09  ? 432 PRO B CG  1 
ATOM   6612  C CD  . PRO B 1 411 ? 187.768 206.465 158.981 1.00 92.09  ? 432 PRO B CD  1 
ATOM   6613  N N   . ASN B 1 412 ? 185.011 207.396 156.457 1.00 96.12  ? 433 ASN B N   1 
ATOM   6614  C CA  . ASN B 1 412 ? 183.738 207.954 156.020 1.00 96.12  ? 433 ASN B CA  1 
ATOM   6615  C C   . ASN B 1 412 ? 183.646 208.166 154.515 1.00 96.12  ? 433 ASN B C   1 
ATOM   6616  O O   . ASN B 1 412 ? 182.538 208.161 153.969 1.00 96.12  ? 433 ASN B O   1 
ATOM   6617  C CB  . ASN B 1 412 ? 183.466 209.288 156.734 1.00 96.12  ? 433 ASN B CB  1 
ATOM   6618  C CG  . ASN B 1 412 ? 184.645 210.258 156.666 1.00 96.12  ? 433 ASN B CG  1 
ATOM   6619  O OD1 . ASN B 1 412 ? 185.141 210.597 155.591 1.00 96.12  ? 433 ASN B OD1 1 
ATOM   6620  N ND2 . ASN B 1 412 ? 185.083 210.722 157.826 1.00 96.12  ? 433 ASN B ND2 1 
ATOM   6621  N N   . ASN B 1 413 ? 184.776 208.353 153.830 1.00 104.97 ? 434 ASN B N   1 
ATOM   6622  C CA  . ASN B 1 413 ? 184.757 208.815 152.449 1.00 104.97 ? 434 ASN B CA  1 
ATOM   6623  C C   . ASN B 1 413 ? 184.950 207.713 151.411 1.00 104.97 ? 434 ASN B C   1 
ATOM   6624  O O   . ASN B 1 413 ? 184.640 207.936 150.236 1.00 104.97 ? 434 ASN B O   1 
ATOM   6625  C CB  . ASN B 1 413 ? 185.810 209.925 152.251 1.00 104.97 ? 434 ASN B CB  1 
ATOM   6626  C CG  . ASN B 1 413 ? 187.248 209.489 152.608 1.00 104.97 ? 434 ASN B CG  1 
ATOM   6627  O OD1 . ASN B 1 413 ? 187.520 208.315 152.859 1.00 104.97 ? 434 ASN B OD1 1 
ATOM   6628  N ND2 . ASN B 1 413 ? 188.177 210.455 152.638 1.00 104.97 ? 434 ASN B ND2 1 
ATOM   6629  N N   . LEU B 1 414 ? 185.446 206.543 151.806 1.00 96.32  ? 435 LEU B N   1 
ATOM   6630  C CA  . LEU B 1 414 ? 185.753 205.503 150.837 1.00 96.32  ? 435 LEU B CA  1 
ATOM   6631  C C   . LEU B 1 414 ? 184.489 204.729 150.468 1.00 96.32  ? 435 LEU B C   1 
ATOM   6632  O O   . LEU B 1 414 ? 183.415 204.919 151.044 1.00 96.32  ? 435 LEU B O   1 
ATOM   6633  C CB  . LEU B 1 414 ? 186.813 204.536 151.374 1.00 96.32  ? 435 LEU B CB  1 
ATOM   6634  C CG  . LEU B 1 414 ? 186.459 203.442 152.395 1.00 96.32  ? 435 LEU B CG  1 
ATOM   6635  C CD1 . LEU B 1 414 ? 187.579 202.415 152.460 1.00 96.32  ? 435 LEU B CD1 1 
ATOM   6636  C CD2 . LEU B 1 414 ? 186.143 203.950 153.782 1.00 96.32  ? 435 LEU B CD2 1 
ATOM   6637  N N   . THR B 1 415 ? 184.632 203.839 149.489 1.00 92.10  ? 436 THR B N   1 
ATOM   6638  C CA  . THR B 1 415 ? 183.526 203.001 149.060 1.00 92.10  ? 436 THR B CA  1 
ATOM   6639  C C   . THR B 1 415 ? 183.273 201.882 150.069 1.00 92.10  ? 436 THR B C   1 
ATOM   6640  O O   . THR B 1 415 ? 184.105 201.577 150.927 1.00 92.10  ? 436 THR B O   1 
ATOM   6641  C CB  . THR B 1 415 ? 183.798 202.413 147.673 1.00 92.10  ? 436 THR B CB  1 
ATOM   6642  O OG1 . THR B 1 415 ? 182.618 201.763 147.186 1.00 92.10  ? 436 THR B OG1 1 
ATOM   6643  C CG2 . THR B 1 415 ? 184.945 201.412 147.721 1.00 92.10  ? 436 THR B CG2 1 
ATOM   6644  N N   . ILE B 1 416 ? 182.092 201.277 149.964 1.00 90.24  ? 437 ILE B N   1 
ATOM   6645  C CA  . ILE B 1 416 ? 181.682 200.201 150.856 1.00 90.24  ? 437 ILE B CA  1 
ATOM   6646  C C   . ILE B 1 416 ? 181.245 199.006 150.023 1.00 90.24  ? 437 ILE B C   1 
ATOM   6647  O O   . ILE B 1 416 ? 180.769 199.149 148.892 1.00 90.24  ? 437 ILE B O   1 
ATOM   6648  C CB  . ILE B 1 416 ? 180.554 200.643 151.815 1.00 90.24  ? 437 ILE B CB  1 
ATOM   6649  C CG1 . ILE B 1 416 ? 179.398 201.272 151.033 1.00 90.24  ? 437 ILE B CG1 1 
ATOM   6650  C CG2 . ILE B 1 416 ? 181.087 201.602 152.869 1.00 90.24  ? 437 ILE B CG2 1 
ATOM   6651  C CD1 . ILE B 1 416 ? 178.183 201.579 151.878 1.00 90.24  ? 437 ILE B CD1 1 
ATOM   6652  N N   . GLU B 1 417 ? 181.420 197.814 150.592 1.00 88.87  ? 438 GLU B N   1 
ATOM   6653  C CA  . GLU B 1 417 ? 181.046 196.557 149.945 1.00 88.87  ? 438 GLU B CA  1 
ATOM   6654  C C   . GLU B 1 417 ? 180.288 195.715 150.966 1.00 88.87  ? 438 GLU B C   1 
ATOM   6655  O O   . GLU B 1 417 ? 180.894 195.116 151.859 1.00 88.87  ? 438 GLU B O   1 
ATOM   6656  C CB  . GLU B 1 417 ? 182.273 195.821 149.414 1.00 88.87  ? 438 GLU B CB  1 
ATOM   6657  C CG  . GLU B 1 417 ? 182.923 196.474 148.202 1.00 88.87  ? 438 GLU B CG  1 
ATOM   6658  C CD  . GLU B 1 417 ? 184.227 195.809 147.808 1.00 88.87  ? 438 GLU B CD  1 
ATOM   6659  O OE1 . GLU B 1 417 ? 184.690 194.918 148.551 1.00 88.87  ? 438 GLU B OE1 1 
ATOM   6660  O OE2 . GLU B 1 417 ? 184.790 196.178 146.756 1.00 88.87  ? 438 GLU B OE2 1 
ATOM   6661  N N   . ILE B 1 418 ? 178.966 195.673 150.832 1.00 71.57  ? 439 ILE B N   1 
ATOM   6662  C CA  . ILE B 1 418 ? 178.118 194.947 151.772 1.00 71.57  ? 439 ILE B CA  1 
ATOM   6663  C C   . ILE B 1 418 ? 178.100 193.473 151.388 1.00 71.57  ? 439 ILE B C   1 
ATOM   6664  O O   . ILE B 1 418 ? 177.812 193.121 150.238 1.00 71.57  ? 439 ILE B O   1 
ATOM   6665  C CB  . ILE B 1 418 ? 176.694 195.537 151.801 1.00 71.57  ? 439 ILE B CB  1 
ATOM   6666  C CG1 . ILE B 1 418 ? 176.678 196.969 152.360 1.00 71.57  ? 439 ILE B CG1 1 
ATOM   6667  C CG2 . ILE B 1 418 ? 175.753 194.658 152.614 1.00 71.57  ? 439 ILE B CG2 1 
ATOM   6668  C CD1 . ILE B 1 418 ? 176.741 198.087 151.320 1.00 71.57  ? 439 ILE B CD1 1 
ATOM   6669  N N   . GLY B 1 419 ? 178.410 192.604 152.353 1.00 71.82  ? 440 GLY B N   1 
ATOM   6670  C CA  . GLY B 1 419 ? 178.443 191.183 152.107 1.00 71.82  ? 440 GLY B CA  1 
ATOM   6671  C C   . GLY B 1 419 ? 177.060 190.564 152.084 1.00 71.82  ? 440 GLY B C   1 
ATOM   6672  O O   . GLY B 1 419 ? 176.034 191.228 152.289 1.00 71.82  ? 440 GLY B O   1 
ATOM   6673  N N   . PRO B 1 420 ? 177.019 189.259 151.824 1.00 80.94  ? 441 PRO B N   1 
ATOM   6674  C CA  . PRO B 1 420 ? 175.735 188.556 151.729 1.00 80.94  ? 441 PRO B CA  1 
ATOM   6675  C C   . PRO B 1 420 ? 175.145 188.295 153.103 1.00 80.94  ? 441 PRO B C   1 
ATOM   6676  O O   . PRO B 1 420 ? 175.879 188.229 154.101 1.00 80.94  ? 441 PRO B O   1 
ATOM   6677  C CB  . PRO B 1 420 ? 176.113 187.246 151.024 1.00 80.94  ? 441 PRO B CB  1 
ATOM   6678  C CG  . PRO B 1 420 ? 177.504 186.991 151.484 1.00 80.94  ? 441 PRO B CG  1 
ATOM   6679  C CD  . PRO B 1 420 ? 178.155 188.352 151.572 1.00 80.94  ? 441 PRO B CD  1 
ATOM   6680  N N   . PRO B 1 421 ? 173.822 188.155 153.203 1.00 89.38  ? 442 PRO B N   1 
ATOM   6681  C CA  . PRO B 1 421 ? 173.220 187.775 154.485 1.00 89.38  ? 442 PRO B CA  1 
ATOM   6682  C C   . PRO B 1 421 ? 173.476 186.313 154.818 1.00 89.38  ? 442 PRO B C   1 
ATOM   6683  O O   . PRO B 1 421 ? 173.577 185.455 153.937 1.00 89.38  ? 442 PRO B O   1 
ATOM   6684  C CB  . PRO B 1 421 ? 171.729 188.048 154.268 1.00 89.38  ? 442 PRO B CB  1 
ATOM   6685  C CG  . PRO B 1 421 ? 171.540 187.863 152.802 1.00 89.38  ? 442 PRO B CG  1 
ATOM   6686  C CD  . PRO B 1 421 ? 172.798 188.402 152.171 1.00 89.38  ? 442 PRO B CD  1 
ATOM   6687  N N   . VAL B 1 422 ? 173.588 186.037 156.117 1.00 90.98  ? 443 VAL B N   1 
ATOM   6688  C CA  . VAL B 1 422 ? 173.901 184.708 156.631 1.00 90.98  ? 443 VAL B CA  1 
ATOM   6689  C C   . VAL B 1 422 ? 172.805 184.299 157.607 1.00 90.98  ? 443 VAL B C   1 
ATOM   6690  O O   . VAL B 1 422 ? 172.472 185.059 158.523 1.00 90.98  ? 443 VAL B O   1 
ATOM   6691  C CB  . VAL B 1 422 ? 175.282 184.672 157.321 1.00 90.98  ? 443 VAL B CB  1 
ATOM   6692  C CG1 . VAL B 1 422 ? 175.570 183.293 157.897 1.00 90.98  ? 443 VAL B CG1 1 
ATOM   6693  C CG2 . VAL B 1 422 ? 176.386 185.078 156.354 1.00 90.98  ? 443 VAL B CG2 1 
ATOM   6694  N N   . TYR B 1 423 ? 172.246 183.107 157.412 1.00 98.12  ? 444 TYR B N   1 
ATOM   6695  C CA  . TYR B 1 423 ? 171.248 182.541 158.308 1.00 98.12  ? 444 TYR B CA  1 
ATOM   6696  C C   . TYR B 1 423 ? 171.810 181.304 159.002 1.00 98.12  ? 444 TYR B C   1 
ATOM   6697  O O   . TYR B 1 423 ? 172.893 180.814 158.674 1.00 98.12  ? 444 TYR B O   1 
ATOM   6698  C CB  . TYR B 1 423 ? 169.965 182.200 157.546 1.00 98.12  ? 444 TYR B CB  1 
ATOM   6699  C CG  . TYR B 1 423 ? 168.953 183.323 157.497 1.00 98.12  ? 444 TYR B CG  1 
ATOM   6700  C CD1 . TYR B 1 423 ? 168.987 184.271 156.479 1.00 98.12  ? 444 TYR B CD1 1 
ATOM   6701  C CD2 . TYR B 1 423 ? 167.959 183.432 158.464 1.00 98.12  ? 444 TYR B CD2 1 
ATOM   6702  C CE1 . TYR B 1 423 ? 168.061 185.300 156.428 1.00 98.12  ? 444 TYR B CE1 1 
ATOM   6703  C CE2 . TYR B 1 423 ? 167.028 184.457 158.422 1.00 98.12  ? 444 TYR B CE2 1 
ATOM   6704  C CZ  . TYR B 1 423 ? 167.085 185.387 157.402 1.00 98.12  ? 444 TYR B CZ  1 
ATOM   6705  O OH  . TYR B 1 423 ? 166.163 186.407 157.356 1.00 98.12  ? 444 TYR B OH  1 
ATOM   6706  N N   . THR B 1 424 ? 171.053 180.796 159.974 1.00 108.07 ? 445 THR B N   1 
ATOM   6707  C CA  . THR B 1 424 ? 171.562 179.803 160.916 1.00 108.07 ? 445 THR B CA  1 
ATOM   6708  C C   . THR B 1 424 ? 170.814 178.477 160.910 1.00 108.07 ? 445 THR B C   1 
ATOM   6709  O O   . THR B 1 424 ? 171.445 177.423 160.785 1.00 108.07 ? 445 THR B O   1 
ATOM   6710  C CB  . THR B 1 424 ? 171.534 180.397 162.338 1.00 108.07 ? 445 THR B CB  1 
ATOM   6711  O OG1 . THR B 1 424 ? 172.409 181.531 162.402 1.00 108.07 ? 445 THR B OG1 1 
ATOM   6712  C CG2 . THR B 1 424 ? 171.955 179.371 163.385 1.00 108.07 ? 445 THR B CG2 1 
ATOM   6713  N N   . GLU B 1 425 ? 169.477 178.501 161.017 1.00 106.91 ? 446 GLU B N   1 
ATOM   6714  C CA  . GLU B 1 425 ? 168.665 177.357 161.415 1.00 106.91 ? 446 GLU B CA  1 
ATOM   6715  C C   . GLU B 1 425 ? 168.610 176.286 160.314 1.00 106.91 ? 446 GLU B C   1 
ATOM   6716  O O   . GLU B 1 425 ? 168.703 176.610 159.127 1.00 106.91 ? 446 GLU B O   1 
ATOM   6717  C CB  . GLU B 1 425 ? 167.263 177.841 161.798 1.00 106.91 ? 446 GLU B CB  1 
ATOM   6718  C CG  . GLU B 1 425 ? 166.436 178.462 160.692 1.00 106.91 ? 446 GLU B CG  1 
ATOM   6719  C CD  . GLU B 1 425 ? 165.464 177.471 160.102 1.00 106.91 ? 446 GLU B CD  1 
ATOM   6720  O OE1 . GLU B 1 425 ? 165.213 176.448 160.771 1.00 106.91 ? 446 GLU B OE1 1 
ATOM   6721  O OE2 . GLU B 1 425 ? 164.943 177.717 158.994 1.00 106.91 ? 446 GLU B OE2 1 
ATOM   6722  N N   . PRO B 1 426 ? 168.503 174.998 160.693 1.00 100.77 ? 447 PRO B N   1 
ATOM   6723  C CA  . PRO B 1 426 ? 168.712 173.916 159.705 1.00 100.77 ? 447 PRO B CA  1 
ATOM   6724  C C   . PRO B 1 426 ? 167.642 173.791 158.627 1.00 100.77 ? 447 PRO B C   1 
ATOM   6725  O O   . PRO B 1 426 ? 167.935 173.246 157.554 1.00 100.77 ? 447 PRO B O   1 
ATOM   6726  C CB  . PRO B 1 426 ? 168.766 172.650 160.575 1.00 100.77 ? 447 PRO B CB  1 
ATOM   6727  C CG  . PRO B 1 426 ? 168.148 173.036 161.872 1.00 100.77 ? 447 PRO B CG  1 
ATOM   6728  C CD  . PRO B 1 426 ? 168.506 174.467 162.068 1.00 100.77 ? 447 PRO B CD  1 
ATOM   6729  N N   . VAL B 1 427 ? 166.412 174.249 158.873 1.00 96.05  ? 448 VAL B N   1 
ATOM   6730  C CA  . VAL B 1 427 ? 165.410 174.255 157.809 1.00 96.05  ? 448 VAL B CA  1 
ATOM   6731  C C   . VAL B 1 427 ? 165.796 175.266 156.734 1.00 96.05  ? 448 VAL B C   1 
ATOM   6732  O O   . VAL B 1 427 ? 165.601 175.027 155.533 1.00 96.05  ? 448 VAL B O   1 
ATOM   6733  C CB  . VAL B 1 427 ? 164.011 174.530 158.394 1.00 96.05  ? 448 VAL B CB  1 
ATOM   6734  C CG1 . VAL B 1 427 ? 162.930 174.460 157.321 1.00 96.05  ? 448 VAL B CG1 1 
ATOM   6735  C CG2 . VAL B 1 427 ? 163.714 173.558 159.526 1.00 96.05  ? 448 VAL B CG2 1 
ATOM   6736  N N   . ASP B 1 428 ? 166.398 176.387 157.148 1.00 102.06 ? 449 ASP B N   1 
ATOM   6737  C CA  . ASP B 1 428 ? 166.884 177.374 156.189 1.00 102.06 ? 449 ASP B CA  1 
ATOM   6738  C C   . ASP B 1 428 ? 168.040 176.830 155.360 1.00 102.06 ? 449 ASP B C   1 
ATOM   6739  O O   . ASP B 1 428 ? 168.136 177.128 154.168 1.00 102.06 ? 449 ASP B O   1 
ATOM   6740  C CB  . ASP B 1 428 ? 167.319 178.655 156.893 1.00 102.06 ? 449 ASP B CB  1 
ATOM   6741  C CG  . ASP B 1 428 ? 167.710 179.742 155.913 1.00 102.06 ? 449 ASP B CG  1 
ATOM   6742  O OD1 . ASP B 1 428 ? 166.810 180.460 155.430 1.00 102.06 ? 449 ASP B OD1 1 
ATOM   6743  O OD2 . ASP B 1 428 ? 168.909 179.842 155.581 1.00 102.06 ? 449 ASP B OD2 1 
ATOM   6744  N N   . ILE B 1 429 ? 168.926 176.027 155.954 1.00 95.95  ? 450 ILE B N   1 
ATOM   6745  C CA  . ILE B 1 429 ? 170.005 175.488 155.132 1.00 95.95  ? 450 ILE B CA  1 
ATOM   6746  C C   . ILE B 1 429 ? 169.529 174.306 154.291 1.00 95.95  ? 450 ILE B C   1 
ATOM   6747  O O   . ILE B 1 429 ? 170.127 174.029 153.247 1.00 95.95  ? 450 ILE B O   1 
ATOM   6748  C CB  . ILE B 1 429 ? 171.256 175.118 155.953 1.00 95.95  ? 450 ILE B CB  1 
ATOM   6749  C CG1 . ILE B 1 429 ? 171.032 173.887 156.821 1.00 95.95  ? 450 ILE B CG1 1 
ATOM   6750  C CG2 . ILE B 1 429 ? 171.694 176.297 156.815 1.00 95.95  ? 450 ILE B CG2 1 
ATOM   6751  C CD1 . ILE B 1 429 ? 172.287 173.387 157.491 1.00 95.95  ? 450 ILE B CD1 1 
ATOM   6752  N N   . THR B 1 430 ? 168.440 173.630 154.678 1.00 99.07  ? 451 THR B N   1 
ATOM   6753  C CA  . THR B 1 430 ? 167.814 172.669 153.768 1.00 99.07  ? 451 THR B CA  1 
ATOM   6754  C C   . THR B 1 430 ? 167.195 173.379 152.561 1.00 99.07  ? 451 THR B C   1 
ATOM   6755  O O   . THR B 1 430 ? 167.334 172.926 151.416 1.00 99.07  ? 451 THR B O   1 
ATOM   6756  C CB  . THR B 1 430 ? 166.771 171.843 154.526 1.00 99.07  ? 451 THR B CB  1 
ATOM   6757  O OG1 . THR B 1 430 ? 167.420 171.112 155.574 1.00 99.07  ? 451 THR B OG1 1 
ATOM   6758  C CG2 . THR B 1 430 ? 166.068 170.853 153.606 1.00 99.07  ? 451 THR B CG2 1 
ATOM   6759  N N   . ASN B 1 431 ? 166.553 174.527 152.792 1.00 99.75  ? 452 ASN B N   1 
ATOM   6760  C CA  . ASN B 1 431 ? 166.103 175.370 151.685 1.00 99.75  ? 452 ASN B CA  1 
ATOM   6761  C C   . ASN B 1 431 ? 167.269 175.961 150.898 1.00 99.75  ? 452 ASN B C   1 
ATOM   6762  O O   . ASN B 1 431 ? 167.118 176.266 149.708 1.00 99.75  ? 452 ASN B O   1 
ATOM   6763  C CB  . ASN B 1 431 ? 165.223 176.494 152.221 1.00 99.75  ? 452 ASN B CB  1 
ATOM   6764  C CG  . ASN B 1 431 ? 164.028 175.977 152.984 1.00 99.75  ? 452 ASN B CG  1 
ATOM   6765  O OD1 . ASN B 1 431 ? 163.786 174.772 153.045 1.00 99.75  ? 452 ASN B OD1 1 
ATOM   6766  N ND2 . ASN B 1 431 ? 163.299 176.884 153.611 1.00 99.75  ? 452 ASN B ND2 1 
ATOM   6767  N N   . GLN B 1 432 ? 168.419 176.144 151.549 1.00 102.48 ? 453 GLN B N   1 
ATOM   6768  C CA  . GLN B 1 432 ? 169.621 176.562 150.840 1.00 102.48 ? 453 GLN B CA  1 
ATOM   6769  C C   . GLN B 1 432 ? 170.124 175.457 149.923 1.00 102.48 ? 453 GLN B C   1 
ATOM   6770  O O   . GLN B 1 432 ? 170.580 175.743 148.817 1.00 102.48 ? 453 GLN B O   1 
ATOM   6771  C CB  . GLN B 1 432 ? 170.702 176.995 151.831 1.00 102.48 ? 453 GLN B CB  1 
ATOM   6772  C CG  . GLN B 1 432 ? 171.854 177.794 151.229 1.00 102.48 ? 453 GLN B CG  1 
ATOM   6773  C CD  . GLN B 1 432 ? 172.979 176.916 150.717 1.00 102.48 ? 453 GLN B CD  1 
ATOM   6774  O OE1 . GLN B 1 432 ? 173.159 175.793 151.185 1.00 102.48 ? 453 GLN B OE1 1 
ATOM   6775  N NE2 . GLN B 1 432 ? 173.744 177.424 149.756 1.00 102.48 ? 453 GLN B NE2 1 
ATOM   6776  N N   . LEU B 1 433 ? 170.053 174.195 150.367 1.00 101.47 ? 454 LEU B N   1 
ATOM   6777  C CA  . LEU B 1 433 ? 170.252 173.060 149.463 1.00 101.47 ? 454 LEU B CA  1 
ATOM   6778  C C   . LEU B 1 433 ? 169.259 173.074 148.310 1.00 101.47 ? 454 LEU B C   1 
ATOM   6779  O O   . LEU B 1 433 ? 169.626 172.759 147.171 1.00 101.47 ? 454 LEU B O   1 
ATOM   6780  C CB  . LEU B 1 433 ? 170.130 171.734 150.213 1.00 101.47 ? 454 LEU B CB  1 
ATOM   6781  C CG  . LEU B 1 433 ? 171.342 171.007 150.788 1.00 101.47 ? 454 LEU B CG  1 
ATOM   6782  C CD1 . LEU B 1 433 ? 171.979 171.689 151.977 1.00 101.47 ? 454 LEU B CD1 1 
ATOM   6783  C CD2 . LEU B 1 433 ? 170.918 169.586 151.152 1.00 101.47 ? 454 LEU B CD2 1 
ATOM   6784  N N   . GLY B 1 434 ? 168.013 173.455 148.588 1.00 101.33 ? 455 GLY B N   1 
ATOM   6785  C CA  . GLY B 1 434 ? 167.012 173.633 147.552 1.00 101.33 ? 455 GLY B CA  1 
ATOM   6786  C C   . GLY B 1 434 ? 167.398 174.634 146.472 1.00 101.33 ? 455 GLY B C   1 
ATOM   6787  O O   . GLY B 1 434 ? 167.529 174.246 145.312 1.00 101.33 ? 455 GLY B O   1 
ATOM   6788  N N   . ASN B 1 435 ? 167.696 175.884 146.878 1.00 99.98  ? 456 ASN B N   1 
ATOM   6789  C CA  . ASN B 1 435 ? 168.022 176.894 145.875 1.00 99.98  ? 456 ASN B CA  1 
ATOM   6790  C C   . ASN B 1 435 ? 169.464 176.807 145.379 1.00 99.98  ? 456 ASN B C   1 
ATOM   6791  O O   . ASN B 1 435 ? 169.808 177.489 144.402 1.00 99.98  ? 456 ASN B O   1 
ATOM   6792  C CB  . ASN B 1 435 ? 167.654 178.327 146.366 1.00 99.98  ? 456 ASN B CB  1 
ATOM   6793  C CG  . ASN B 1 435 ? 168.455 178.815 147.593 1.00 99.98  ? 456 ASN B CG  1 
ATOM   6794  O OD1 . ASN B 1 435 ? 169.444 178.234 148.018 1.00 99.98  ? 456 ASN B OD1 1 
ATOM   6795  N ND2 . ASN B 1 435 ? 167.988 179.927 148.161 1.00 99.98  ? 456 ASN B ND2 1 
ATOM   6796  N N   . ILE B 1 436 ? 170.305 175.972 146.000 1.00 104.46 ? 457 ILE B N   1 
ATOM   6797  C CA  . ILE B 1 436 ? 171.416 175.373 145.259 1.00 104.46 ? 457 ILE B CA  1 
ATOM   6798  C C   . ILE B 1 436 ? 170.865 174.565 144.099 1.00 104.46 ? 457 ILE B C   1 
ATOM   6799  O O   . ILE B 1 436 ? 171.291 174.731 142.957 1.00 104.46 ? 457 ILE B O   1 
ATOM   6800  C CB  . ILE B 1 436 ? 172.298 174.485 146.172 1.00 104.46 ? 457 ILE B CB  1 
ATOM   6801  C CG1 . ILE B 1 436 ? 173.223 175.287 147.086 1.00 104.46 ? 457 ILE B CG1 1 
ATOM   6802  C CG2 . ILE B 1 436 ? 173.131 173.495 145.359 1.00 104.46 ? 457 ILE B CG2 1 
ATOM   6803  C CD1 . ILE B 1 436 ? 173.921 174.431 148.120 1.00 104.46 ? 457 ILE B CD1 1 
ATOM   6804  N N   . ASN B 1 437 ? 169.870 173.710 144.371 1.00 113.05 ? 458 ASN B N   1 
ATOM   6805  C CA  . ASN B 1 437 ? 169.639 172.572 143.491 1.00 113.05 ? 458 ASN B CA  1 
ATOM   6806  C C   . ASN B 1 437 ? 168.798 172.941 142.262 1.00 113.05 ? 458 ASN B C   1 
ATOM   6807  O O   . ASN B 1 437 ? 169.061 172.410 141.170 1.00 113.05 ? 458 ASN B O   1 
ATOM   6808  C CB  . ASN B 1 437 ? 169.018 171.452 144.331 1.00 113.05 ? 458 ASN B CB  1 
ATOM   6809  C CG  . ASN B 1 437 ? 169.070 170.083 143.670 1.00 113.05 ? 458 ASN B CG  1 
ATOM   6810  O OD1 . ASN B 1 437 ? 169.510 169.915 142.538 1.00 113.05 ? 458 ASN B OD1 1 
ATOM   6811  N ND2 . ASN B 1 437 ? 168.678 169.081 144.437 1.00 113.05 ? 458 ASN B ND2 1 
ATOM   6812  N N   . GLU B 1 438 ? 167.817 173.862 142.387 1.00 106.04 ? 459 GLU B N   1 
ATOM   6813  C CA  . GLU B 1 438 ? 167.134 174.307 141.158 1.00 106.04 ? 459 GLU B CA  1 
ATOM   6814  C C   . GLU B 1 438 ? 168.088 175.086 140.255 1.00 106.04 ? 459 GLU B C   1 
ATOM   6815  O O   . GLU B 1 438 ? 168.039 174.945 139.027 1.00 106.04 ? 459 GLU B O   1 
ATOM   6816  C CB  . GLU B 1 438 ? 165.873 175.177 141.347 1.00 106.04 ? 459 GLU B CB  1 
ATOM   6817  C CG  . GLU B 1 438 ? 164.611 174.602 141.966 1.00 106.04 ? 459 GLU B CG  1 
ATOM   6818  C CD  . GLU B 1 438 ? 164.521 174.776 143.458 1.00 106.04 ? 459 GLU B CD  1 
ATOM   6819  O OE1 . GLU B 1 438 ? 165.401 175.443 144.016 1.00 106.04 ? 459 GLU B OE1 1 
ATOM   6820  O OE2 . GLU B 1 438 ? 163.532 174.314 144.058 1.00 106.04 ? 459 GLU B OE2 1 
ATOM   6821  N N   . THR B 1 439 ? 168.941 175.926 140.849 1.00 102.33 ? 460 THR B N   1 
ATOM   6822  C CA  . THR B 1 439 ? 169.954 176.654 140.088 1.00 102.33 ? 460 THR B CA  1 
ATOM   6823  C C   . THR B 1 439 ? 170.948 175.687 139.449 1.00 102.33 ? 460 THR B C   1 
ATOM   6824  O O   . THR B 1 439 ? 171.394 175.895 138.314 1.00 102.33 ? 460 THR B O   1 
ATOM   6825  C CB  . THR B 1 439 ? 170.648 177.652 141.023 1.00 102.33 ? 460 THR B CB  1 
ATOM   6826  O OG1 . THR B 1 439 ? 169.688 178.617 141.468 1.00 102.33 ? 460 THR B OG1 1 
ATOM   6827  C CG2 . THR B 1 439 ? 171.783 178.395 140.328 1.00 102.33 ? 460 THR B CG2 1 
ATOM   6828  N N   . LEU B 1 440 ? 171.245 174.588 140.148 1.00 101.13 ? 461 LEU B N   1 
ATOM   6829  C CA  . LEU B 1 440 ? 172.130 173.546 139.641 1.00 101.13 ? 461 LEU B CA  1 
ATOM   6830  C C   . LEU B 1 440 ? 171.545 172.864 138.409 1.00 101.13 ? 461 LEU B C   1 
ATOM   6831  O O   . LEU B 1 440 ? 172.253 172.626 137.423 1.00 101.13 ? 461 LEU B O   1 
ATOM   6832  C CB  . LEU B 1 440 ? 172.380 172.526 140.751 1.00 101.13 ? 461 LEU B CB  1 
ATOM   6833  C CG  . LEU B 1 440 ? 173.428 171.440 140.558 1.00 101.13 ? 461 LEU B CG  1 
ATOM   6834  C CD1 . LEU B 1 440 ? 174.791 172.075 140.551 1.00 101.13 ? 461 LEU B CD1 1 
ATOM   6835  C CD2 . LEU B 1 440 ? 173.319 170.408 141.664 1.00 101.13 ? 461 LEU B CD2 1 
ATOM   6836  N N   . SER B 1 441 ? 170.249 172.560 138.439 1.00 103.98 ? 462 SER B N   1 
ATOM   6837  C CA  . SER B 1 441 ? 169.614 171.906 137.300 1.00 103.98 ? 462 SER B CA  1 
ATOM   6838  C C   . SER B 1 441 ? 169.245 172.858 136.169 1.00 103.98 ? 462 SER B C   1 
ATOM   6839  O O   . SER B 1 441 ? 169.407 172.497 135.003 1.00 103.98 ? 462 SER B O   1 
ATOM   6840  C CB  . SER B 1 441 ? 168.354 171.166 137.759 1.00 103.98 ? 462 SER B CB  1 
ATOM   6841  O OG  . SER B 1 441 ? 168.620 170.398 138.917 1.00 103.98 ? 462 SER B OG  1 
ATOM   6842  N N   . LYS B 1 442 ? 169.159 174.188 136.441 1.00 100.34 ? 463 LYS B N   1 
ATOM   6843  C CA  . LYS B 1 442 ? 169.301 175.227 135.379 1.00 100.34 ? 463 LYS B CA  1 
ATOM   6844  C C   . LYS B 1 442 ? 170.690 175.252 134.752 1.00 100.34 ? 463 LYS B C   1 
ATOM   6845  O O   . LYS B 1 442 ? 170.807 175.392 133.530 1.00 100.34 ? 463 LYS B O   1 
ATOM   6846  C CB  . LYS B 1 442 ? 168.944 176.619 135.916 1.00 100.34 ? 463 LYS B CB  1 
ATOM   6847  C CG  . LYS B 1 442 ? 167.494 176.796 136.362 1.00 100.34 ? 463 LYS B CG  1 
ATOM   6848  C CD  . LYS B 1 442 ? 166.475 176.286 135.332 1.00 100.34 ? 463 LYS B CD  1 
ATOM   6849  C CE  . LYS B 1 442 ? 166.450 177.138 134.061 1.00 100.34 ? 463 LYS B CE  1 
ATOM   6850  N NZ  . LYS B 1 442 ? 166.455 178.591 134.372 1.00 100.34 ? 463 LYS B NZ  1 
ATOM   6851  N N   . THR B 1 443 ? 171.754 175.142 135.560 1.00 103.22 ? 464 THR B N   1 
ATOM   6852  C CA  . THR B 1 443 ? 173.103 175.163 134.990 1.00 103.22 ? 464 THR B CA  1 
ATOM   6853  C C   . THR B 1 443 ? 173.367 173.925 134.144 1.00 103.22 ? 464 THR B C   1 
ATOM   6854  O O   . THR B 1 443 ? 174.000 174.018 133.091 1.00 103.22 ? 464 THR B O   1 
ATOM   6855  C CB  . THR B 1 443 ? 174.183 175.289 136.071 1.00 103.22 ? 464 THR B CB  1 
ATOM   6856  O OG1 . THR B 1 443 ? 174.040 174.248 137.043 1.00 103.22 ? 464 THR B OG1 1 
ATOM   6857  C CG2 . THR B 1 443 ? 174.163 176.661 136.733 1.00 103.22 ? 464 THR B CG2 1 
ATOM   6858  N N   . LEU B 1 444 ? 172.870 172.763 134.574 1.00 103.73 ? 465 LEU B N   1 
ATOM   6859  C CA  . LEU B 1 444 ? 173.012 171.551 133.769 1.00 103.73 ? 465 LEU B CA  1 
ATOM   6860  C C   . LEU B 1 444 ? 172.187 171.607 132.483 1.00 103.73 ? 465 LEU B C   1 
ATOM   6861  O O   . LEU B 1 444 ? 172.653 171.137 131.431 1.00 103.73 ? 465 LEU B O   1 
ATOM   6862  C CB  . LEU B 1 444 ? 172.630 170.322 134.595 1.00 103.73 ? 465 LEU B CB  1 
ATOM   6863  C CG  . LEU B 1 444 ? 173.556 170.019 135.777 1.00 103.73 ? 465 LEU B CG  1 
ATOM   6864  C CD1 . LEU B 1 444 ? 173.024 168.865 136.616 1.00 103.73 ? 465 LEU B CD1 1 
ATOM   6865  C CD2 . LEU B 1 444 ? 174.971 169.733 135.292 1.00 103.73 ? 465 LEU B CD2 1 
ATOM   6866  N N   . ASP B 1 445 ? 170.984 172.195 132.540 1.00 110.75 ? 466 ASP B N   1 
ATOM   6867  C CA  . ASP B 1 445 ? 170.191 172.381 131.328 1.00 110.75 ? 466 ASP B CA  1 
ATOM   6868  C C   . ASP B 1 445 ? 170.864 173.353 130.365 1.00 110.75 ? 466 ASP B C   1 
ATOM   6869  O O   . ASP B 1 445 ? 170.860 173.128 129.149 1.00 110.75 ? 466 ASP B O   1 
ATOM   6870  C CB  . ASP B 1 445 ? 168.785 172.862 131.685 1.00 110.75 ? 466 ASP B CB  1 
ATOM   6871  C CG  . ASP B 1 445 ? 167.939 171.772 132.314 1.00 110.75 ? 466 ASP B CG  1 
ATOM   6872  O OD1 . ASP B 1 445 ? 168.327 170.588 132.221 1.00 110.75 ? 466 ASP B OD1 1 
ATOM   6873  O OD2 . ASP B 1 445 ? 166.886 172.099 132.901 1.00 110.75 ? 466 ASP B OD2 1 
ATOM   6874  N N   . LEU B 1 446 ? 171.463 174.426 130.889 1.00 103.49 ? 467 LEU B N   1 
ATOM   6875  C CA  . LEU B 1 446 ? 172.239 175.331 130.050 1.00 103.49 ? 467 LEU B CA  1 
ATOM   6876  C C   . LEU B 1 446 ? 173.514 174.695 129.516 1.00 103.49 ? 467 LEU B C   1 
ATOM   6877  O O   . LEU B 1 446 ? 173.930 175.052 128.414 1.00 103.49 ? 467 LEU B O   1 
ATOM   6878  C CB  . LEU B 1 446 ? 172.583 176.617 130.805 1.00 103.49 ? 467 LEU B CB  1 
ATOM   6879  C CG  . LEU B 1 446 ? 171.415 177.555 131.118 1.00 103.49 ? 467 LEU B CG  1 
ATOM   6880  C CD1 . LEU B 1 446 ? 171.866 178.694 132.018 1.00 103.49 ? 467 LEU B CD1 1 
ATOM   6881  C CD2 . LEU B 1 446 ? 170.805 178.091 129.831 1.00 103.49 ? 467 LEU B CD2 1 
ATOM   6882  N N   . ILE B 1 447 ? 174.121 173.759 130.257 1.00 104.12 ? 468 ILE B N   1 
ATOM   6883  C CA  . ILE B 1 447 ? 175.249 172.984 129.737 1.00 104.12 ? 468 ILE B CA  1 
ATOM   6884  C C   . ILE B 1 447 ? 174.823 172.169 128.522 1.00 104.12 ? 468 ILE B C   1 
ATOM   6885  O O   . ILE B 1 447 ? 175.488 172.193 127.478 1.00 104.12 ? 468 ILE B O   1 
ATOM   6886  C CB  . ILE B 1 447 ? 175.846 172.087 130.842 1.00 104.12 ? 468 ILE B CB  1 
ATOM   6887  C CG1 . ILE B 1 447 ? 176.740 172.892 131.786 1.00 104.12 ? 468 ILE B CG1 1 
ATOM   6888  C CG2 . ILE B 1 447 ? 176.607 170.889 130.269 1.00 104.12 ? 468 ILE B CG2 1 
ATOM   6889  C CD1 . ILE B 1 447 ? 177.129 172.128 133.031 1.00 104.12 ? 468 ILE B CD1 1 
ATOM   6890  N N   . LYS B 1 448 ? 173.685 171.470 128.631 1.00 107.75 ? 469 LYS B N   1 
ATOM   6891  C CA  . LYS B 1 448 ? 173.207 170.644 127.520 1.00 107.75 ? 469 LYS B CA  1 
ATOM   6892  C C   . LYS B 1 448 ? 172.813 171.490 126.309 1.00 107.75 ? 469 LYS B C   1 
ATOM   6893  O O   . LYS B 1 448 ? 173.212 171.184 125.172 1.00 107.75 ? 469 LYS B O   1 
ATOM   6894  C CB  . LYS B 1 448 ? 172.030 169.783 127.977 1.00 107.75 ? 469 LYS B CB  1 
ATOM   6895  C CG  . LYS B 1 448 ? 172.404 168.705 128.980 1.00 107.75 ? 469 LYS B CG  1 
ATOM   6896  C CD  . LYS B 1 448 ? 171.190 167.890 129.393 1.00 107.75 ? 469 LYS B CD  1 
ATOM   6897  C CE  . LYS B 1 448 ? 171.571 166.788 130.369 1.00 107.75 ? 469 LYS B CE  1 
ATOM   6898  N NZ  . LYS B 1 448 ? 170.389 165.988 130.793 1.00 107.75 ? 469 LYS B NZ  1 
ATOM   6899  N N   . GLN B 1 449 ? 172.069 172.580 126.546 1.00 110.12 ? 470 GLN B N   1 
ATOM   6900  C CA  . GLN B 1 449 ? 171.652 173.472 125.465 1.00 110.12 ? 470 GLN B CA  1 
ATOM   6901  C C   . GLN B 1 449 ? 172.847 174.144 124.802 1.00 110.12 ? 470 GLN B C   1 
ATOM   6902  O O   . GLN B 1 449 ? 172.947 174.169 123.570 1.00 110.12 ? 470 GLN B O   1 
ATOM   6903  C CB  . GLN B 1 449 ? 170.683 174.530 125.996 1.00 110.12 ? 470 GLN B CB  1 
ATOM   6904  C CG  . GLN B 1 449 ? 169.314 174.009 126.390 1.00 110.12 ? 470 GLN B CG  1 
ATOM   6905  C CD  . GLN B 1 449 ? 168.450 175.089 127.010 1.00 110.12 ? 470 GLN B CD  1 
ATOM   6906  O OE1 . GLN B 1 449 ? 168.960 176.053 127.583 1.00 110.12 ? 470 GLN B OE1 1 
ATOM   6907  N NE2 . GLN B 1 449 ? 167.137 174.936 126.897 1.00 110.12 ? 470 GLN B NE2 1 
ATOM   6908  N N   . SER B 1 450 ? 173.782 174.664 125.608 1.00 107.29 ? 471 SER B N   1 
ATOM   6909  C CA  . SER B 1 450 ? 174.960 175.336 125.081 1.00 107.29 ? 471 SER B CA  1 
ATOM   6910  C C   . SER B 1 450 ? 175.859 174.384 124.310 1.00 107.29 ? 471 SER B C   1 
ATOM   6911  O O   . SER B 1 450 ? 176.354 174.757 123.248 1.00 107.29 ? 471 SER B O   1 
ATOM   6912  C CB  . SER B 1 450 ? 175.738 175.996 126.219 1.00 107.29 ? 471 SER B CB  1 
ATOM   6913  O OG  . SER B 1 450 ? 176.237 175.028 127.125 1.00 107.29 ? 471 SER B OG  1 
ATOM   6914  N N   . ASN B 1 451 ? 176.039 173.149 124.793 1.00 110.64 ? 472 ASN B N   1 
ATOM   6915  C CA  . ASN B 1 451 ? 176.895 172.197 124.091 1.00 110.64 ? 472 ASN B CA  1 
ATOM   6916  C C   . ASN B 1 451 ? 176.264 171.702 122.794 1.00 110.64 ? 472 ASN B C   1 
ATOM   6917  O O   . ASN B 1 451 ? 176.992 171.362 121.853 1.00 110.64 ? 472 ASN B O   1 
ATOM   6918  C CB  . ASN B 1 451 ? 177.234 171.020 125.005 1.00 110.64 ? 472 ASN B CB  1 
ATOM   6919  C CG  . ASN B 1 451 ? 178.219 171.397 126.097 1.00 110.64 ? 472 ASN B CG  1 
ATOM   6920  O OD1 . ASN B 1 451 ? 178.967 172.366 125.966 1.00 110.64 ? 472 ASN B OD1 1 
ATOM   6921  N ND2 . ASN B 1 451 ? 178.223 170.631 127.181 1.00 110.64 ? 472 ASN B ND2 1 
ATOM   6922  N N   . SER B 1 452 ? 174.929 171.635 122.719 1.00 113.04 ? 473 SER B N   1 
ATOM   6923  C CA  . SER B 1 452 ? 174.302 171.361 121.425 1.00 113.04 ? 473 SER B CA  1 
ATOM   6924  C C   . SER B 1 452 ? 174.460 172.543 120.469 1.00 113.04 ? 473 SER B C   1 
ATOM   6925  O O   . SER B 1 452 ? 174.710 172.363 119.262 1.00 113.04 ? 473 SER B O   1 
ATOM   6926  C CB  . SER B 1 452 ? 172.825 171.022 121.620 1.00 113.04 ? 473 SER B CB  1 
ATOM   6927  O OG  . SER B 1 452 ? 172.119 172.120 122.171 1.00 113.04 ? 473 SER B OG  1 
ATOM   6928  N N   . ILE B 1 453 ? 174.331 173.767 120.993 1.00 114.69 ? 474 ILE B N   1 
ATOM   6929  C CA  . ILE B 1 453 ? 174.434 174.940 120.131 1.00 114.69 ? 474 ILE B CA  1 
ATOM   6930  C C   . ILE B 1 453 ? 175.871 175.205 119.691 1.00 114.69 ? 474 ILE B C   1 
ATOM   6931  O O   . ILE B 1 453 ? 176.077 175.803 118.623 1.00 114.69 ? 474 ILE B O   1 
ATOM   6932  C CB  . ILE B 1 453 ? 173.704 176.101 120.841 1.00 114.69 ? 474 ILE B CB  1 
ATOM   6933  C CG1 . ILE B 1 453 ? 172.208 175.793 120.912 1.00 114.69 ? 474 ILE B CG1 1 
ATOM   6934  C CG2 . ILE B 1 453 ? 173.745 177.369 120.044 1.00 114.69 ? 474 ILE B CG2 1 
ATOM   6935  C CD1 . ILE B 1 453 ? 171.425 176.727 121.814 1.00 114.69 ? 474 ILE B CD1 1 
ATOM   6936  N N   . LEU B 1 454 ? 176.868 174.694 120.429 1.00 114.59 ? 475 LEU B N   1 
ATOM   6937  C CA  . LEU B 1 454 ? 178.250 174.736 119.944 1.00 114.59 ? 475 LEU B CA  1 
ATOM   6938  C C   . LEU B 1 454 ? 178.389 173.965 118.637 1.00 114.59 ? 475 LEU B C   1 
ATOM   6939  O O   . LEU B 1 454 ? 178.879 174.500 117.639 1.00 114.59 ? 475 LEU B O   1 
ATOM   6940  C CB  . LEU B 1 454 ? 179.234 174.162 120.972 1.00 114.59 ? 475 LEU B CB  1 
ATOM   6941  C CG  . LEU B 1 454 ? 179.431 174.677 122.403 1.00 114.59 ? 475 LEU B CG  1 
ATOM   6942  C CD1 . LEU B 1 454 ? 180.545 173.918 123.130 1.00 114.59 ? 475 LEU B CD1 1 
ATOM   6943  C CD2 . LEU B 1 454 ? 179.577 176.194 122.513 1.00 114.59 ? 475 LEU B CD2 1 
ATOM   6944  N N   . ASP B 1 455 ? 177.881 172.735 118.599 1.00 117.55 ? 476 ASP B N   1 
ATOM   6945  C CA  . ASP B 1 455 ? 178.018 171.935 117.391 1.00 117.55 ? 476 ASP B CA  1 
ATOM   6946  C C   . ASP B 1 455 ? 177.046 172.325 116.285 1.00 117.55 ? 476 ASP B C   1 
ATOM   6947  O O   . ASP B 1 455 ? 177.256 171.907 115.141 1.00 117.55 ? 476 ASP B O   1 
ATOM   6948  C CB  . ASP B 1 455 ? 177.871 170.448 117.711 1.00 117.55 ? 476 ASP B CB  1 
ATOM   6949  C CG  . ASP B 1 455 ? 179.089 169.889 118.417 1.00 117.55 ? 476 ASP B CG  1 
ATOM   6950  O OD1 . ASP B 1 455 ? 180.135 170.573 118.423 1.00 117.55 ? 476 ASP B OD1 1 
ATOM   6951  O OD2 . ASP B 1 455 ? 179.009 168.764 118.951 1.00 117.55 ? 476 ASP B OD2 1 
ATOM   6952  N N   . MET B 1 456 ? 175.993 173.104 116.564 1.00 118.79 ? 477 MET B N   1 
ATOM   6953  C CA  . MET B 1 456 ? 175.293 173.669 115.406 1.00 118.79 ? 477 MET B CA  1 
ATOM   6954  C C   . MET B 1 456 ? 175.919 174.995 114.971 1.00 118.79 ? 477 MET B C   1 
ATOM   6955  O O   . MET B 1 456 ? 175.620 175.495 113.881 1.00 118.79 ? 477 MET B O   1 
ATOM   6956  C CB  . MET B 1 456 ? 173.781 173.813 115.642 1.00 118.79 ? 477 MET B CB  1 
ATOM   6957  C CG  . MET B 1 456 ? 173.282 174.738 116.731 1.00 118.79 ? 477 MET B CG  1 
ATOM   6958  S SD  . MET B 1 456 ? 173.207 176.511 116.373 1.00 118.79 ? 477 MET B SD  1 
ATOM   6959  C CE  . MET B 1 456 ? 171.846 176.570 115.210 1.00 118.79 ? 477 MET B CE  1 
ATOM   6960  N N   . ILE B 1 457 ? 176.785 175.583 115.803 1.00 115.41 ? 478 ILE B N   1 
ATOM   6961  C CA  . ILE B 1 457 ? 177.536 176.762 115.371 1.00 115.41 ? 478 ILE B CA  1 
ATOM   6962  C C   . ILE B 1 457 ? 178.891 176.365 114.791 1.00 115.41 ? 478 ILE B C   1 
ATOM   6963  O O   . ILE B 1 457 ? 179.238 176.758 113.670 1.00 115.41 ? 478 ILE B O   1 
ATOM   6964  C CB  . ILE B 1 457 ? 177.681 177.775 116.526 1.00 115.41 ? 478 ILE B CB  1 
ATOM   6965  C CG1 . ILE B 1 457 ? 176.347 178.477 116.797 1.00 115.41 ? 478 ILE B CG1 1 
ATOM   6966  C CG2 . ILE B 1 457 ? 178.758 178.813 116.225 1.00 115.41 ? 478 ILE B CG2 1 
ATOM   6967  C CD1 . ILE B 1 457 ? 176.340 179.306 118.066 1.00 115.41 ? 478 ILE B CD1 1 
ATOM   6968  N N   . THR B 1 458 ? 179.676 175.577 115.531 1.00 111.50 ? 479 THR B N   1 
ATOM   6969  C CA  . THR B 1 458 ? 181.008 175.192 115.070 1.00 111.50 ? 479 THR B CA  1 
ATOM   6970  C C   . THR B 1 458 ? 180.950 174.150 113.959 1.00 111.50 ? 479 THR B C   1 
ATOM   6971  O O   . THR B 1 458 ? 181.734 174.213 113.007 1.00 111.50 ? 479 THR B O   1 
ATOM   6972  C CB  . THR B 1 458 ? 181.847 174.645 116.231 1.00 111.50 ? 479 THR B CB  1 
ATOM   6973  O OG1 . THR B 1 458 ? 181.245 173.444 116.730 1.00 111.50 ? 479 THR B OG1 1 
ATOM   6974  C CG2 . THR B 1 458 ? 181.916 175.653 117.355 1.00 111.50 ? 479 THR B CG2 1 
ATOM   6975  N N   . GLY B 1 459 ? 180.051 173.172 114.085 1.00 103.62 ? 480 GLY B N   1 
ATOM   6976  C CA  . GLY B 1 459 ? 179.926 172.155 113.053 1.00 103.62 ? 480 GLY B CA  1 
ATOM   6977  C C   . GLY B 1 459 ? 179.342 172.687 111.758 1.00 103.62 ? 480 GLY B C   1 
ATOM   6978  O O   . GLY B 1 459 ? 179.794 172.323 110.669 1.00 103.62 ? 480 GLY B O   1 
ATOM   6979  N N   . GLY B 1 460 ? 178.327 173.548 111.858 1.00 103.17 ? 481 GLY B N   1 
ATOM   6980  C CA  . GLY B 1 460 ? 177.659 174.034 110.659 1.00 103.17 ? 481 GLY B CA  1 
ATOM   6981  C C   . GLY B 1 460 ? 178.486 175.041 109.881 1.00 103.17 ? 481 GLY B C   1 
ATOM   6982  O O   . GLY B 1 460 ? 178.557 174.975 108.649 1.00 103.17 ? 481 GLY B O   1 
ATOM   6983  N N   . LEU B 1 461 ? 179.133 175.970 110.596 1.00 102.00 ? 482 LEU B N   1 
ATOM   6984  C CA  . LEU B 1 461 ? 179.860 177.131 110.049 1.00 102.00 ? 482 LEU B CA  1 
ATOM   6985  C C   . LEU B 1 461 ? 179.028 177.956 109.066 1.00 102.00 ? 482 LEU B C   1 
ATOM   6986  O O   . LEU B 1 461 ? 177.851 178.223 109.307 1.00 102.00 ? 482 LEU B O   1 
ATOM   6987  C CB  . LEU B 1 461 ? 181.174 176.702 109.380 1.00 102.00 ? 482 LEU B CB  1 
ATOM   6988  C CG  . LEU B 1 461 ? 182.242 176.079 110.278 1.00 102.00 ? 482 LEU B CG  1 
ATOM   6989  C CD1 . LEU B 1 461 ? 183.417 175.579 109.451 1.00 102.00 ? 482 LEU B CD1 1 
ATOM   6990  C CD2 . LEU B 1 461 ? 182.706 177.077 111.328 1.00 102.00 ? 482 LEU B CD2 1 
ATOM   6991  N N   . VAL C 1 1   ? 181.302 146.095 162.954 1.00 78.72  ? 22  VAL C N   1 
ATOM   6992  C CA  . VAL C 1 1   ? 182.281 147.170 162.869 1.00 78.72  ? 22  VAL C CA  1 
ATOM   6993  C C   . VAL C 1 1   ? 183.694 146.588 162.705 1.00 78.72  ? 22  VAL C C   1 
ATOM   6994  O O   . VAL C 1 1   ? 184.037 145.560 163.295 1.00 78.72  ? 22  VAL C O   1 
ATOM   6995  C CB  . VAL C 1 1   ? 182.149 148.131 164.101 1.00 78.72  ? 22  VAL C CB  1 
ATOM   6996  C CG1 . VAL C 1 1   ? 182.470 147.431 165.420 1.00 78.72  ? 22  VAL C CG1 1 
ATOM   6997  C CG2 . VAL C 1 1   ? 182.999 149.386 163.925 1.00 78.72  ? 22  VAL C CG2 1 
ATOM   6998  N N   . ASP C 1 2   ? 184.490 147.214 161.839 1.00 82.82  ? 23  ASP C N   1 
ATOM   6999  C CA  . ASP C 1 2   ? 185.875 146.821 161.608 1.00 82.82  ? 23  ASP C CA  1 
ATOM   7000  C C   . ASP C 1 2   ? 186.778 147.837 162.297 1.00 82.82  ? 23  ASP C C   1 
ATOM   7001  O O   . ASP C 1 2   ? 186.885 148.984 161.853 1.00 82.82  ? 23  ASP C O   1 
ATOM   7002  C CB  . ASP C 1 2   ? 186.174 146.736 160.112 1.00 82.82  ? 23  ASP C CB  1 
ATOM   7003  C CG  . ASP C 1 2   ? 187.444 145.960 159.811 1.00 82.82  ? 23  ASP C CG  1 
ATOM   7004  O OD1 . ASP C 1 2   ? 188.544 146.498 160.053 1.00 82.82  ? 23  ASP C OD1 1 
ATOM   7005  O OD2 . ASP C 1 2   ? 187.341 144.812 159.329 1.00 82.82  ? 23  ASP C OD2 1 
ATOM   7006  N N   . PHE C 1 3   ? 187.430 147.415 163.381 1.00 73.45  ? 24  PHE C N   1 
ATOM   7007  C CA  . PHE C 1 3   ? 188.287 148.321 164.134 1.00 73.45  ? 24  PHE C CA  1 
ATOM   7008  C C   . PHE C 1 3   ? 189.618 148.590 163.446 1.00 73.45  ? 24  PHE C C   1 
ATOM   7009  O O   . PHE C 1 3   ? 190.293 149.558 163.802 1.00 73.45  ? 24  PHE C O   1 
ATOM   7010  C CB  . PHE C 1 3   ? 188.552 147.767 165.536 1.00 73.45  ? 24  PHE C CB  1 
ATOM   7011  C CG  . PHE C 1 3   ? 187.321 147.652 166.387 1.00 73.45  ? 24  PHE C CG  1 
ATOM   7012  C CD1 . PHE C 1 3   ? 186.656 148.787 166.827 1.00 73.45  ? 24  PHE C CD1 1 
ATOM   7013  C CD2 . PHE C 1 3   ? 186.840 146.406 166.765 1.00 73.45  ? 24  PHE C CD2 1 
ATOM   7014  C CE1 . PHE C 1 3   ? 185.521 148.683 167.613 1.00 73.45  ? 24  PHE C CE1 1 
ATOM   7015  C CE2 . PHE C 1 3   ? 185.709 146.294 167.555 1.00 73.45  ? 24  PHE C CE2 1 
ATOM   7016  C CZ  . PHE C 1 3   ? 185.051 147.435 167.981 1.00 73.45  ? 24  PHE C CZ  1 
ATOM   7017  N N   . GLU C 1 4   ? 190.009 147.762 162.477 1.00 79.90  ? 25  GLU C N   1 
ATOM   7018  C CA  . GLU C 1 4   ? 191.337 147.881 161.882 1.00 79.90  ? 25  GLU C CA  1 
ATOM   7019  C C   . GLU C 1 4   ? 191.427 149.059 160.917 1.00 79.90  ? 25  GLU C C   1 
ATOM   7020  O O   . GLU C 1 4   ? 192.391 149.831 160.959 1.00 79.90  ? 25  GLU C O   1 
ATOM   7021  C CB  . GLU C 1 4   ? 191.709 146.576 161.182 1.00 79.90  ? 25  GLU C CB  1 
ATOM   7022  C CG  . GLU C 1 4   ? 192.226 145.513 162.134 1.00 79.90  ? 25  GLU C CG  1 
ATOM   7023  C CD  . GLU C 1 4   ? 191.117 144.791 162.876 1.00 79.90  ? 25  GLU C CD  1 
ATOM   7024  O OE1 . GLU C 1 4   ? 189.962 144.826 162.404 1.00 79.90  ? 25  GLU C OE1 1 
ATOM   7025  O OE2 . GLU C 1 4   ? 191.403 144.188 163.932 1.00 79.90  ? 25  GLU C OE2 1 
ATOM   7026  N N   . ARG C 1 5   ? 190.425 149.221 160.049 1.00 77.64  ? 26  ARG C N   1 
ATOM   7027  C CA  . ARG C 1 5   ? 190.407 150.368 159.143 1.00 77.64  ? 26  ARG C CA  1 
ATOM   7028  C C   . ARG C 1 5   ? 190.175 151.668 159.905 1.00 77.64  ? 26  ARG C C   1 
ATOM   7029  O O   . ARG C 1 5   ? 190.764 152.708 159.576 1.00 77.64  ? 26  ARG C O   1 
ATOM   7030  C CB  . ARG C 1 5   ? 189.332 150.171 158.076 1.00 77.64  ? 26  ARG C CB  1 
ATOM   7031  C CG  . ARG C 1 5   ? 189.320 148.793 157.439 1.00 77.64  ? 26  ARG C CG  1 
ATOM   7032  C CD  . ARG C 1 5   ? 188.447 148.781 156.195 1.00 77.64  ? 26  ARG C CD  1 
ATOM   7033  N NE  . ARG C 1 5   ? 188.920 149.723 155.187 1.00 77.64  ? 26  ARG C NE  1 
ATOM   7034  C CZ  . ARG C 1 5   ? 189.871 149.460 154.301 1.00 77.64  ? 26  ARG C CZ  1 
ATOM   7035  N NH1 . ARG C 1 5   ? 190.457 148.275 154.247 1.00 77.64  ? 26  ARG C NH1 1 
ATOM   7036  N NH2 . ARG C 1 5   ? 190.238 150.407 153.444 1.00 77.64  ? 26  ARG C NH2 1 
ATOM   7037  N N   . LEU C 1 6   ? 189.336 151.620 160.941 1.00 63.80  ? 27  LEU C N   1 
ATOM   7038  C CA  . LEU C 1 6   ? 189.083 152.796 161.760 1.00 63.80  ? 27  LEU C CA  1 
ATOM   7039  C C   . LEU C 1 6   ? 190.275 153.130 162.651 1.00 63.80  ? 27  LEU C C   1 
ATOM   7040  O O   . LEU C 1 6   ? 190.412 154.279 163.079 1.00 63.80  ? 27  LEU C O   1 
ATOM   7041  C CB  . LEU C 1 6   ? 187.805 152.570 162.576 1.00 63.80  ? 27  LEU C CB  1 
ATOM   7042  C CG  . LEU C 1 6   ? 187.047 153.733 163.219 1.00 63.80  ? 27  LEU C CG  1 
ATOM   7043  C CD1 . LEU C 1 6   ? 185.562 153.436 163.168 1.00 63.80  ? 27  LEU C CD1 1 
ATOM   7044  C CD2 . LEU C 1 6   ? 187.461 153.946 164.655 1.00 63.80  ? 27  LEU C CD2 1 
ATOM   7045  N N   . ALA C 1 7   ? 191.142 152.153 162.933 1.00 62.41  ? 28  ALA C N   1 
ATOM   7046  C CA  . ALA C 1 7   ? 192.425 152.440 163.562 1.00 62.41  ? 28  ALA C CA  1 
ATOM   7047  C C   . ALA C 1 7   ? 193.434 152.974 162.558 1.00 62.41  ? 28  ALA C C   1 
ATOM   7048  O O   . ALA C 1 7   ? 194.318 153.755 162.929 1.00 62.41  ? 28  ALA C O   1 
ATOM   7049  C CB  . ALA C 1 7   ? 192.973 151.186 164.244 1.00 62.41  ? 28  ALA C CB  1 
ATOM   7050  N N   . SER C 1 8   ? 193.325 152.550 161.296 1.00 68.92  ? 29  SER C N   1 
ATOM   7051  C CA  . SER C 1 8   ? 194.182 153.092 160.247 1.00 68.92  ? 29  SER C CA  1 
ATOM   7052  C C   . SER C 1 8   ? 193.863 154.553 159.962 1.00 68.92  ? 29  SER C C   1 
ATOM   7053  O O   . SER C 1 8   ? 194.761 155.321 159.597 1.00 68.92  ? 29  SER C O   1 
ATOM   7054  C CB  . SER C 1 8   ? 194.040 152.266 158.969 1.00 68.92  ? 29  SER C CB  1 
ATOM   7055  O OG  . SER C 1 8   ? 194.214 150.885 159.226 1.00 68.92  ? 29  SER C OG  1 
ATOM   7056  N N   . ILE C 1 9   ? 192.601 154.957 160.117 1.00 66.14  ? 30  ILE C N   1 
ATOM   7057  C CA  . ILE C 1 9   ? 192.252 156.359 159.910 1.00 66.14  ? 30  ILE C CA  1 
ATOM   7058  C C   . ILE C 1 9   ? 192.502 157.203 161.162 1.00 66.14  ? 30  ILE C C   1 
ATOM   7059  O O   . ILE C 1 9   ? 192.639 158.431 161.057 1.00 66.14  ? 30  ILE C O   1 
ATOM   7060  C CB  . ILE C 1 9   ? 190.796 156.477 159.410 1.00 66.14  ? 30  ILE C CB  1 
ATOM   7061  C CG1 . ILE C 1 9   ? 190.561 157.808 158.690 1.00 66.14  ? 30  ILE C CG1 1 
ATOM   7062  C CG2 . ILE C 1 9   ? 189.797 156.325 160.543 1.00 66.14  ? 30  ILE C CG2 1 
ATOM   7063  C CD1 . ILE C 1 9   ? 189.274 157.858 157.926 1.00 66.14  ? 30  ILE C CD1 1 
ATOM   7064  N N   . GLY C 1 10  ? 192.625 156.583 162.336 1.00 50.74  ? 31  GLY C N   1 
ATOM   7065  C CA  . GLY C 1 10  ? 192.952 157.341 163.530 1.00 50.74  ? 31  GLY C CA  1 
ATOM   7066  C C   . GLY C 1 10  ? 191.942 157.289 164.659 1.00 50.74  ? 31  GLY C C   1 
ATOM   7067  O O   . GLY C 1 10  ? 191.816 158.253 165.421 1.00 50.74  ? 31  GLY C O   1 
ATOM   7068  N N   . GLY C 1 11  ? 191.214 156.183 164.781 1.00 43.53  ? 32  GLY C N   1 
ATOM   7069  C CA  . GLY C 1 11  ? 190.313 155.995 165.903 1.00 43.53  ? 32  GLY C CA  1 
ATOM   7070  C C   . GLY C 1 11  ? 190.538 154.663 166.590 1.00 43.53  ? 32  GLY C C   1 
ATOM   7071  O O   . GLY C 1 11  ? 190.485 153.613 165.947 1.00 43.53  ? 32  GLY C O   1 
ATOM   7072  N N   . ILE C 1 12  ? 190.784 154.683 167.893 1.00 32.59  ? 33  ILE C N   1 
ATOM   7073  C CA  . ILE C 1 12  ? 191.214 153.501 168.630 1.00 32.59  ? 33  ILE C CA  1 
ATOM   7074  C C   . ILE C 1 12  ? 190.066 153.005 169.495 1.00 32.59  ? 33  ILE C C   1 
ATOM   7075  O O   . ILE C 1 12  ? 189.354 153.801 170.120 1.00 32.59  ? 33  ILE C O   1 
ATOM   7076  C CB  . ILE C 1 12  ? 192.463 153.825 169.468 1.00 32.59  ? 33  ILE C CB  1 
ATOM   7077  C CG1 . ILE C 1 12  ? 193.450 154.613 168.604 1.00 32.59  ? 33  ILE C CG1 1 
ATOM   7078  C CG2 . ILE C 1 12  ? 193.100 152.555 170.010 1.00 32.59  ? 33  ILE C CG2 1 
ATOM   7079  C CD1 . ILE C 1 12  ? 194.732 154.964 169.280 1.00 32.59  ? 33  ILE C CD1 1 
ATOM   7080  N N   . LYS C 1 13  ? 189.871 151.687 169.512 1.00 34.64  ? 34  LYS C N   1 
ATOM   7081  C CA  . LYS C 1 13  ? 188.779 151.087 170.266 1.00 34.64  ? 34  LYS C CA  1 
ATOM   7082  C C   . LYS C 1 13  ? 189.029 151.197 171.765 1.00 34.64  ? 34  LYS C C   1 
ATOM   7083  O O   . LYS C 1 13  ? 190.097 150.822 172.259 1.00 34.64  ? 34  LYS C O   1 
ATOM   7084  C CB  . LYS C 1 13  ? 188.607 149.623 169.865 1.00 34.64  ? 34  LYS C CB  1 
ATOM   7085  C CG  . LYS C 1 13  ? 187.505 148.893 170.615 1.00 34.64  ? 34  LYS C CG  1 
ATOM   7086  C CD  . LYS C 1 13  ? 187.718 147.389 170.584 1.00 34.64  ? 34  LYS C CD  1 
ATOM   7087  C CE  . LYS C 1 13  ? 188.959 146.988 171.363 1.00 34.64  ? 34  LYS C CE  1 
ATOM   7088  N NZ  . LYS C 1 13  ? 188.903 147.458 172.774 1.00 34.64  ? 34  LYS C NZ  1 
ATOM   7089  N N   . GLY C 1 14  ? 188.041 151.708 172.484 1.00 30.90  ? 35  GLY C N   1 
ATOM   7090  C CA  . GLY C 1 14  ? 188.099 151.875 173.918 1.00 30.90  ? 35  GLY C CA  1 
ATOM   7091  C C   . GLY C 1 14  ? 187.457 150.724 174.661 1.00 30.90  ? 35  GLY C C   1 
ATOM   7092  O O   . GLY C 1 14  ? 187.409 149.588 174.175 1.00 30.90  ? 35  GLY C O   1 
ATOM   7093  N N   . HIS C 1 15  ? 186.957 151.020 175.856 1.00 29.20  ? 36  HIS C N   1 
ATOM   7094  C CA  . HIS C 1 15  ? 186.338 150.009 176.697 1.00 29.20  ? 36  HIS C CA  1 
ATOM   7095  C C   . HIS C 1 15  ? 184.935 149.674 176.202 1.00 29.20  ? 36  HIS C C   1 
ATOM   7096  O O   . HIS C 1 15  ? 184.349 150.380 175.376 1.00 29.20  ? 36  HIS C O   1 
ATOM   7097  C CB  . HIS C 1 15  ? 186.275 150.480 178.150 1.00 29.20  ? 36  HIS C CB  1 
ATOM   7098  C CG  . HIS C 1 15  ? 187.476 151.258 178.587 1.00 29.20  ? 36  HIS C CG  1 
ATOM   7099  N ND1 . HIS C 1 15  ? 187.583 152.621 178.416 1.00 29.20  ? 36  HIS C ND1 1 
ATOM   7100  C CD2 . HIS C 1 15  ? 188.623 150.863 179.188 1.00 29.20  ? 36  HIS C CD2 1 
ATOM   7101  C CE1 . HIS C 1 15  ? 188.744 153.033 178.893 1.00 29.20  ? 36  HIS C CE1 1 
ATOM   7102  N NE2 . HIS C 1 15  ? 189.394 151.986 179.368 1.00 29.20  ? 36  HIS C NE2 1 
ATOM   7103  N N   . SER C 1 16  ? 184.400 148.573 176.720 1.00 29.70  ? 37  SER C N   1 
ATOM   7104  C CA  . SER C 1 16  ? 183.035 148.147 176.447 1.00 29.70  ? 37  SER C CA  1 
ATOM   7105  C C   . SER C 1 16  ? 182.245 148.154 177.747 1.00 29.70  ? 37  SER C C   1 
ATOM   7106  O O   . SER C 1 16  ? 182.655 147.527 178.729 1.00 29.70  ? 37  SER C O   1 
ATOM   7107  C CB  . SER C 1 16  ? 183.010 146.755 175.815 1.00 29.70  ? 37  SER C CB  1 
ATOM   7108  O OG  . SER C 1 16  ? 183.643 146.761 174.548 1.00 29.70  ? 37  SER C OG  1 
ATOM   7109  N N   . LYS C 1 17  ? 181.117 148.858 177.750 1.00 28.95  ? 38  LYS C N   1 
ATOM   7110  C CA  . LYS C 1 17  ? 180.295 149.007 178.941 1.00 28.95  ? 38  LYS C CA  1 
ATOM   7111  C C   . LYS C 1 17  ? 178.865 148.588 178.634 1.00 28.95  ? 38  LYS C C   1 
ATOM   7112  O O   . LYS C 1 17  ? 178.418 148.615 177.485 1.00 28.95  ? 38  LYS C O   1 
ATOM   7113  C CB  . LYS C 1 17  ? 180.324 150.449 179.468 1.00 28.95  ? 38  LYS C CB  1 
ATOM   7114  C CG  . LYS C 1 17  ? 181.690 150.901 179.954 1.00 28.95  ? 38  LYS C CG  1 
ATOM   7115  C CD  . LYS C 1 17  ? 181.657 152.333 180.453 1.00 28.95  ? 38  LYS C CD  1 
ATOM   7116  C CE  . LYS C 1 17  ? 183.049 152.825 180.812 1.00 28.95  ? 38  LYS C CE  1 
ATOM   7117  N NZ  . LYS C 1 17  ? 183.596 152.121 182.004 1.00 28.95  ? 38  LYS C NZ  1 
ATOM   7118  N N   . LEU C 1 18  ? 178.152 148.190 179.684 1.00 28.41  ? 39  LEU C N   1 
ATOM   7119  C CA  . LEU C 1 18  ? 176.776 147.739 179.553 1.00 28.41  ? 39  LEU C CA  1 
ATOM   7120  C C   . LEU C 1 18  ? 175.828 148.937 179.555 1.00 28.41  ? 39  LEU C C   1 
ATOM   7121  O O   . LEU C 1 18  ? 176.240 150.093 179.681 1.00 28.41  ? 39  LEU C O   1 
ATOM   7122  C CB  . LEU C 1 18  ? 176.425 146.759 180.671 1.00 28.41  ? 39  LEU C CB  1 
ATOM   7123  C CG  . LEU C 1 18  ? 176.775 145.277 180.504 1.00 28.41  ? 39  LEU C CG  1 
ATOM   7124  C CD1 . LEU C 1 18  ? 178.252 144.998 180.747 1.00 28.41  ? 39  LEU C CD1 1 
ATOM   7125  C CD2 . LEU C 1 18  ? 175.920 144.434 181.433 1.00 28.41  ? 39  LEU C CD2 1 
ATOM   7126  N N   . TYR C 1 19  ? 174.533 148.657 179.423 1.00 30.46  ? 40  TYR C N   1 
ATOM   7127  C CA  . TYR C 1 19  ? 173.512 149.698 179.369 1.00 30.46  ? 40  TYR C CA  1 
ATOM   7128  C C   . TYR C 1 19  ? 172.369 149.301 180.290 1.00 30.46  ? 40  TYR C C   1 
ATOM   7129  O O   . TYR C 1 19  ? 171.810 148.211 180.147 1.00 30.46  ? 40  TYR C O   1 
ATOM   7130  C CB  . TYR C 1 19  ? 173.011 149.892 177.936 1.00 30.46  ? 40  TYR C CB  1 
ATOM   7131  C CG  . TYR C 1 19  ? 172.259 151.180 177.707 1.00 30.46  ? 40  TYR C CG  1 
ATOM   7132  C CD1 . TYR C 1 19  ? 172.600 152.336 178.395 1.00 30.46  ? 40  TYR C CD1 1 
ATOM   7133  C CD2 . TYR C 1 19  ? 171.214 151.243 176.793 1.00 30.46  ? 40  TYR C CD2 1 
ATOM   7134  C CE1 . TYR C 1 19  ? 171.919 153.518 178.184 1.00 30.46  ? 40  TYR C CE1 1 
ATOM   7135  C CE2 . TYR C 1 19  ? 170.527 152.423 176.573 1.00 30.46  ? 40  TYR C CE2 1 
ATOM   7136  C CZ  . TYR C 1 19  ? 170.884 153.556 177.273 1.00 30.46  ? 40  TYR C CZ  1 
ATOM   7137  O OH  . TYR C 1 19  ? 170.204 154.732 177.062 1.00 30.46  ? 40  TYR C OH  1 
ATOM   7138  N N   . LYS C 1 20  ? 172.025 150.176 181.235 1.00 29.34  ? 41  LYS C N   1 
ATOM   7139  C CA  . LYS C 1 20  ? 170.977 149.893 182.205 1.00 29.34  ? 41  LYS C CA  1 
ATOM   7140  C C   . LYS C 1 20  ? 170.082 151.111 182.384 1.00 29.34  ? 41  LYS C C   1 
ATOM   7141  O O   . LYS C 1 20  ? 170.565 152.246 182.449 1.00 29.34  ? 41  LYS C O   1 
ATOM   7142  C CB  . LYS C 1 20  ? 171.571 149.462 183.551 1.00 29.34  ? 41  LYS C CB  1 
ATOM   7143  C CG  . LYS C 1 20  ? 171.836 147.965 183.639 1.00 29.34  ? 41  LYS C CG  1 
ATOM   7144  C CD  . LYS C 1 20  ? 172.580 147.573 184.906 1.00 29.34  ? 41  LYS C CD  1 
ATOM   7145  C CE  . LYS C 1 20  ? 173.840 148.396 185.103 1.00 29.34  ? 41  LYS C CE  1 
ATOM   7146  N NZ  . LYS C 1 20  ? 174.387 148.242 186.477 1.00 29.34  ? 41  LYS C NZ  1 
ATOM   7147  N N   . ILE C 1 21  ? 168.775 150.864 182.465 1.00 33.11  ? 42  ILE C N   1 
ATOM   7148  C CA  . ILE C 1 21  ? 167.756 151.907 182.495 1.00 33.11  ? 42  ILE C CA  1 
ATOM   7149  C C   . ILE C 1 21  ? 166.950 151.761 183.781 1.00 33.11  ? 42  ILE C C   1 
ATOM   7150  O O   . ILE C 1 21  ? 166.666 150.641 184.219 1.00 33.11  ? 42  ILE C O   1 
ATOM   7151  C CB  . ILE C 1 21  ? 166.832 151.826 181.256 1.00 33.11  ? 42  ILE C CB  1 
ATOM   7152  C CG1 . ILE C 1 21  ? 167.647 151.751 179.965 1.00 33.11  ? 42  ILE C CG1 1 
ATOM   7153  C CG2 . ILE C 1 21  ? 165.907 153.031 181.160 1.00 33.11  ? 42  ILE C CG2 1 
ATOM   7154  C CD1 . ILE C 1 21  ? 166.818 151.429 178.742 1.00 33.11  ? 42  ILE C CD1 1 
ATOM   7155  N N   . LYS C 1 22  ? 166.612 152.891 184.403 1.00 45.69  ? 43  LYS C N   1 
ATOM   7156  C CA  . LYS C 1 22  ? 165.641 152.889 185.490 1.00 45.69  ? 43  LYS C CA  1 
ATOM   7157  C C   . LYS C 1 22  ? 164.262 152.518 184.957 1.00 45.69  ? 43  LYS C C   1 
ATOM   7158  O O   . LYS C 1 22  ? 163.825 153.036 183.924 1.00 45.69  ? 43  LYS C O   1 
ATOM   7159  C CB  . LYS C 1 22  ? 165.589 154.261 186.160 1.00 45.69  ? 43  LYS C CB  1 
ATOM   7160  C CG  . LYS C 1 22  ? 164.705 154.315 187.397 1.00 45.69  ? 43  LYS C CG  1 
ATOM   7161  C CD  . LYS C 1 22  ? 164.458 155.746 187.848 1.00 45.69  ? 43  LYS C CD  1 
ATOM   7162  C CE  . LYS C 1 22  ? 163.246 156.350 187.157 1.00 45.69  ? 43  LYS C CE  1 
ATOM   7163  N NZ  . LYS C 1 22  ? 161.971 155.753 187.641 1.00 45.69  ? 43  LYS C NZ  1 
ATOM   7164  N N   . GLY C 1 23  ? 163.574 151.626 185.660 1.00 60.10  ? 44  GLY C N   1 
ATOM   7165  C CA  . GLY C 1 23  ? 162.247 151.217 185.233 1.00 60.10  ? 44  GLY C CA  1 
ATOM   7166  C C   . GLY C 1 23  ? 161.598 150.324 186.264 1.00 60.10  ? 44  GLY C C   1 
ATOM   7167  O O   . GLY C 1 23  ? 162.236 149.876 187.221 1.00 60.10  ? 44  GLY C O   1 
ATOM   7168  N N   . HIS C 1 24  ? 160.306 150.052 186.026 1.00 84.36  ? 45  HIS C N   1 
ATOM   7169  C CA  . HIS C 1 24  ? 159.384 149.290 186.871 1.00 84.36  ? 45  HIS C CA  1 
ATOM   7170  C C   . HIS C 1 24  ? 159.394 149.755 188.327 1.00 84.36  ? 45  HIS C C   1 
ATOM   7171  O O   . HIS C 1 24  ? 159.869 149.017 189.200 1.00 84.36  ? 45  HIS C O   1 
ATOM   7172  C CB  . HIS C 1 24  ? 159.705 147.793 186.812 1.00 84.36  ? 45  HIS C CB  1 
ATOM   7173  C CG  . HIS C 1 24  ? 160.100 147.305 185.451 1.00 84.36  ? 45  HIS C CG  1 
ATOM   7174  N ND1 . HIS C 1 24  ? 161.393 147.377 184.979 1.00 84.36  ? 45  HIS C ND1 1 
ATOM   7175  C CD2 . HIS C 1 24  ? 159.370 146.737 184.463 1.00 84.36  ? 45  HIS C CD2 1 
ATOM   7176  C CE1 . HIS C 1 24  ? 161.442 146.875 183.758 1.00 84.36  ? 45  HIS C CE1 1 
ATOM   7177  N NE2 . HIS C 1 24  ? 160.228 146.479 183.421 1.00 84.36  ? 45  HIS C NE2 1 
ATOM   7178  N N   . PRO C 1 25  ? 158.890 150.947 188.641 1.00 53.70  ? 46  PRO C N   1 
ATOM   7179  C CA  . PRO C 1 25  ? 158.999 151.444 190.013 1.00 53.70  ? 46  PRO C CA  1 
ATOM   7180  C C   . PRO C 1 25  ? 157.801 151.109 190.888 1.00 53.70  ? 46  PRO C C   1 
ATOM   7181  O O   . PRO C 1 25  ? 156.667 150.958 190.431 1.00 53.70  ? 46  PRO C O   1 
ATOM   7182  C CB  . PRO C 1 25  ? 159.112 152.962 189.812 1.00 53.70  ? 46  PRO C CB  1 
ATOM   7183  C CG  . PRO C 1 25  ? 158.366 153.233 188.534 1.00 53.70  ? 46  PRO C CG  1 
ATOM   7184  C CD  . PRO C 1 25  ? 158.244 151.940 187.760 1.00 53.70  ? 46  PRO C CD  1 
ATOM   7185  N N   . THR C 1 26  ? 158.082 150.984 192.179 1.00 40.34  ? 47  THR C N   1 
ATOM   7186  C CA  . THR C 1 26  ? 157.055 150.987 193.208 1.00 40.34  ? 47  THR C CA  1 
ATOM   7187  C C   . THR C 1 26  ? 157.017 152.359 193.872 1.00 40.34  ? 47  THR C C   1 
ATOM   7188  O O   . THR C 1 26  ? 157.948 153.157 193.749 1.00 40.34  ? 47  THR C O   1 
ATOM   7189  C CB  . THR C 1 26  ? 157.306 149.887 194.245 1.00 40.34  ? 47  THR C CB  1 
ATOM   7190  O OG1 . THR C 1 26  ? 156.248 149.884 195.212 1.00 40.34  ? 47  THR C OG1 1 
ATOM   7191  C CG2 . THR C 1 26  ? 158.637 150.094 194.942 1.00 40.34  ? 47  THR C CG2 1 
ATOM   7192  N N   . THR C 1 27  ? 155.918 152.639 194.562 1.00 34.32  ? 48  THR C N   1 
ATOM   7193  C CA  . THR C 1 27  ? 155.669 153.965 195.109 1.00 34.32  ? 48  THR C CA  1 
ATOM   7194  C C   . THR C 1 27  ? 155.630 153.915 196.629 1.00 34.32  ? 48  THR C C   1 
ATOM   7195  O O   . THR C 1 27  ? 155.165 152.933 197.216 1.00 34.32  ? 48  THR C O   1 
ATOM   7196  C CB  . THR C 1 27  ? 154.353 154.537 194.579 1.00 34.32  ? 48  THR C CB  1 
ATOM   7197  O OG1 . THR C 1 27  ? 153.299 153.592 194.797 1.00 34.32  ? 48  THR C OG1 1 
ATOM   7198  C CG2 . THR C 1 27  ? 154.464 154.827 193.090 1.00 34.32  ? 48  THR C CG2 1 
ATOM   7199  N N   . LYS C 1 28  ? 156.124 154.977 197.264 1.00 20.55  ? 49  LYS C N   1 
ATOM   7200  C CA  . LYS C 1 28  ? 156.095 155.087 198.714 1.00 20.55  ? 49  LYS C CA  1 
ATOM   7201  C C   . LYS C 1 28  ? 155.786 156.526 199.111 1.00 20.55  ? 49  LYS C C   1 
ATOM   7202  O O   . LYS C 1 28  ? 156.238 157.479 198.467 1.00 20.55  ? 49  LYS C O   1 
ATOM   7203  C CB  . LYS C 1 28  ? 157.421 154.609 199.330 1.00 20.55  ? 49  LYS C CB  1 
ATOM   7204  C CG  . LYS C 1 28  ? 157.407 154.488 200.845 1.00 20.55  ? 49  LYS C CG  1 
ATOM   7205  C CD  . LYS C 1 28  ? 158.719 153.962 201.370 1.00 20.55  ? 49  LYS C CD  1 
ATOM   7206  C CE  . LYS C 1 28  ? 158.886 152.490 201.041 1.00 20.55  ? 49  LYS C CE  1 
ATOM   7207  N NZ  . LYS C 1 28  ? 157.910 151.641 201.777 1.00 20.55  ? 49  LYS C NZ  1 
ATOM   7208  N N   . ASP C 1 29  ? 155.009 156.670 200.184 1.00 23.80  ? 50  ASP C N   1 
ATOM   7209  C CA  . ASP C 1 29  ? 154.475 157.951 200.625 1.00 23.80  ? 50  ASP C CA  1 
ATOM   7210  C C   . ASP C 1 29  ? 155.268 158.474 201.814 1.00 23.80  ? 50  ASP C C   1 
ATOM   7211  O O   . ASP C 1 29  ? 155.537 157.730 202.763 1.00 23.80  ? 50  ASP C O   1 
ATOM   7212  C CB  . ASP C 1 29  ? 153.001 157.816 201.011 1.00 23.80  ? 50  ASP C CB  1 
ATOM   7213  C CG  . ASP C 1 29  ? 152.090 157.729 199.807 1.00 23.80  ? 50  ASP C CG  1 
ATOM   7214  O OD1 . ASP C 1 29  ? 152.235 158.559 198.889 1.00 23.80  ? 50  ASP C OD1 1 
ATOM   7215  O OD2 . ASP C 1 29  ? 151.233 156.825 199.775 1.00 23.80  ? 50  ASP C OD2 1 
ATOM   7216  N N   . ILE C 1 30  ? 155.640 159.753 201.756 1.00 14.63  ? 51  ILE C N   1 
ATOM   7217  C CA  . ILE C 1 30  ? 156.224 160.468 202.881 1.00 14.63  ? 51  ILE C CA  1 
ATOM   7218  C C   . ILE C 1 30  ? 155.389 161.719 203.109 1.00 14.63  ? 51  ILE C C   1 
ATOM   7219  O O   . ILE C 1 30  ? 154.564 162.102 202.279 1.00 14.63  ? 51  ILE C O   1 
ATOM   7220  C CB  . ILE C 1 30  ? 157.704 160.844 202.653 1.00 14.63  ? 51  ILE C CB  1 
ATOM   7221  C CG1 . ILE C 1 30  ? 157.842 161.754 201.435 1.00 14.63  ? 51  ILE C CG1 1 
ATOM   7222  C CG2 . ILE C 1 30  ? 158.555 159.606 202.474 1.00 14.63  ? 51  ILE C CG2 1 
ATOM   7223  C CD1 . ILE C 1 30  ? 159.233 162.320 201.261 1.00 14.63  ? 51  ILE C CD1 1 
ATOM   7224  N N   . VAL C 1 31  ? 155.585 162.343 204.266 1.00 19.90  ? 52  VAL C N   1 
ATOM   7225  C CA  . VAL C 1 31  ? 154.931 163.606 204.586 1.00 19.90  ? 52  VAL C CA  1 
ATOM   7226  C C   . VAL C 1 31  ? 155.980 164.597 205.065 1.00 19.90  ? 52  VAL C C   1 
ATOM   7227  O O   . VAL C 1 31  ? 156.938 164.226 205.752 1.00 19.90  ? 52  VAL C O   1 
ATOM   7228  C CB  . VAL C 1 31  ? 153.803 163.439 205.631 1.00 19.90  ? 52  VAL C CB  1 
ATOM   7229  C CG1 . VAL C 1 31  ? 152.628 162.714 205.028 1.00 19.90  ? 52  VAL C CG1 1 
ATOM   7230  C CG2 . VAL C 1 31  ? 154.283 162.657 206.819 1.00 19.90  ? 52  VAL C CG2 1 
ATOM   7231  N N   . ILE C 1 32  ? 155.822 165.855 204.662 1.00 22.13  ? 53  ILE C N   1 
ATOM   7232  C CA  . ILE C 1 32  ? 156.716 166.934 205.057 1.00 22.13  ? 53  ILE C CA  1 
ATOM   7233  C C   . ILE C 1 32  ? 155.860 168.024 205.681 1.00 22.13  ? 53  ILE C C   1 
ATOM   7234  O O   . ILE C 1 32  ? 155.037 168.641 204.996 1.00 22.13  ? 53  ILE C O   1 
ATOM   7235  C CB  . ILE C 1 32  ? 157.521 167.492 203.875 1.00 22.13  ? 53  ILE C CB  1 
ATOM   7236  C CG1 . ILE C 1 32  ? 158.380 166.401 203.239 1.00 22.13  ? 53  ILE C CG1 1 
ATOM   7237  C CG2 . ILE C 1 32  ? 158.384 168.657 204.321 1.00 22.13  ? 53  ILE C CG2 1 
ATOM   7238  C CD1 . ILE C 1 32  ? 158.895 166.765 201.877 1.00 22.13  ? 53  ILE C CD1 1 
ATOM   7239  N N   . LYS C 1 33  ? 156.045 168.260 206.973 1.00 49.69  ? 54  LYS C N   1 
ATOM   7240  C CA  . LYS C 1 33  ? 155.423 169.415 207.590 1.00 49.69  ? 54  LYS C CA  1 
ATOM   7241  C C   . LYS C 1 33  ? 156.294 170.643 207.353 1.00 49.69  ? 54  LYS C C   1 
ATOM   7242  O O   . LYS C 1 33  ? 157.496 170.542 207.097 1.00 49.69  ? 54  LYS C O   1 
ATOM   7243  C CB  . LYS C 1 33  ? 155.200 169.176 209.083 1.00 49.69  ? 54  LYS C CB  1 
ATOM   7244  C CG  . LYS C 1 33  ? 156.476 169.022 209.896 1.00 49.69  ? 54  LYS C CG  1 
ATOM   7245  C CD  . LYS C 1 33  ? 156.245 168.301 211.224 1.00 49.69  ? 54  LYS C CD  1 
ATOM   7246  C CE  . LYS C 1 33  ? 154.982 168.770 211.933 1.00 49.69  ? 54  LYS C CE  1 
ATOM   7247  N NZ  . LYS C 1 33  ? 155.094 170.182 212.383 1.00 49.69  ? 54  LYS C NZ  1 
ATOM   7248  N N   . LEU C 1 34  ? 155.671 171.815 207.409 1.00 25.30  ? 55  LEU C N   1 
ATOM   7249  C CA  . LEU C 1 34  ? 156.371 173.058 207.111 1.00 25.30  ? 55  LEU C CA  1 
ATOM   7250  C C   . LEU C 1 34  ? 156.520 173.975 208.313 1.00 25.30  ? 55  LEU C C   1 
ATOM   7251  O O   . LEU C 1 34  ? 157.507 174.707 208.401 1.00 25.30  ? 55  LEU C O   1 
ATOM   7252  C CB  . LEU C 1 34  ? 155.656 173.808 205.981 1.00 25.30  ? 55  LEU C CB  1 
ATOM   7253  C CG  . LEU C 1 34  ? 155.893 173.291 204.558 1.00 25.30  ? 55  LEU C CG  1 
ATOM   7254  C CD1 . LEU C 1 34  ? 155.444 174.316 203.533 1.00 25.30  ? 55  LEU C CD1 1 
ATOM   7255  C CD2 . LEU C 1 34  ? 157.351 172.913 204.328 1.00 25.30  ? 55  LEU C CD2 1 
ATOM   7256  N N   . VAL C 1 35  ? 155.572 173.956 209.243 1.00 28.96  ? 56  VAL C N   1 
ATOM   7257  C CA  . VAL C 1 35  ? 155.665 174.765 210.454 1.00 28.96  ? 56  VAL C CA  1 
ATOM   7258  C C   . VAL C 1 35  ? 156.457 173.988 211.499 1.00 28.96  ? 56  VAL C C   1 
ATOM   7259  O O   . VAL C 1 35  ? 156.067 172.867 211.854 1.00 28.96  ? 56  VAL C O   1 
ATOM   7260  C CB  . VAL C 1 35  ? 154.272 175.141 210.980 1.00 28.96  ? 56  VAL C CB  1 
ATOM   7261  C CG1 . VAL C 1 35  ? 154.383 175.843 212.323 1.00 28.96  ? 56  VAL C CG1 1 
ATOM   7262  C CG2 . VAL C 1 35  ? 153.550 176.010 209.971 1.00 28.96  ? 56  VAL C CG2 1 
ATOM   7263  N N   . PRO C 1 36  ? 157.568 174.525 212.006 1.00 30.70  ? 57  PRO C N   1 
ATOM   7264  C CA  . PRO C 1 36  ? 158.329 173.808 213.039 1.00 30.70  ? 57  PRO C CA  1 
ATOM   7265  C C   . PRO C 1 36  ? 157.596 173.825 214.374 1.00 30.70  ? 57  PRO C C   1 
ATOM   7266  O O   . PRO C 1 36  ? 157.112 174.866 214.823 1.00 30.70  ? 57  PRO C O   1 
ATOM   7267  C CB  . PRO C 1 36  ? 159.651 174.580 213.106 1.00 30.70  ? 57  PRO C CB  1 
ATOM   7268  C CG  . PRO C 1 36  ? 159.305 175.951 212.631 1.00 30.70  ? 57  PRO C CG  1 
ATOM   7269  C CD  . PRO C 1 36  ? 158.244 175.763 211.582 1.00 30.70  ? 57  PRO C CD  1 
ATOM   7270  N N   . ASN C 1 37  ? 157.512 172.656 215.003 1.00 46.03  ? 58  ASN C N   1 
ATOM   7271  C CA  . ASN C 1 37  ? 156.783 172.515 216.256 1.00 46.03  ? 58  ASN C CA  1 
ATOM   7272  C C   . ASN C 1 37  ? 157.670 172.944 217.416 1.00 46.03  ? 58  ASN C C   1 
ATOM   7273  O O   . ASN C 1 37  ? 158.714 172.333 217.667 1.00 46.03  ? 58  ASN C O   1 
ATOM   7274  C CB  . ASN C 1 37  ? 156.317 171.074 216.442 1.00 46.03  ? 58  ASN C CB  1 
ATOM   7275  C CG  . ASN C 1 37  ? 155.582 170.862 217.753 1.00 46.03  ? 58  ASN C CG  1 
ATOM   7276  O OD1 . ASN C 1 37  ? 154.866 171.745 218.227 1.00 46.03  ? 58  ASN C OD1 1 
ATOM   7277  N ND2 . ASN C 1 37  ? 155.760 169.689 218.348 1.00 46.03  ? 58  ASN C ND2 1 
ATOM   7278  N N   . LEU C 1 38  ? 157.255 173.991 218.124 1.00 53.41  ? 59  LEU C N   1 
ATOM   7279  C CA  . LEU C 1 38  ? 157.958 174.470 219.304 1.00 53.41  ? 59  LEU C CA  1 
ATOM   7280  C C   . LEU C 1 38  ? 157.034 174.370 220.510 1.00 53.41  ? 59  LEU C C   1 
ATOM   7281  O O   . LEU C 1 38  ? 155.876 174.794 220.450 1.00 53.41  ? 59  LEU C O   1 
ATOM   7282  C CB  . LEU C 1 38  ? 158.473 175.905 219.093 1.00 53.41  ? 59  LEU C CB  1 
ATOM   7283  C CG  . LEU C 1 38  ? 157.568 177.095 218.742 1.00 53.41  ? 59  LEU C CG  1 
ATOM   7284  C CD1 . LEU C 1 38  ? 157.063 177.848 219.971 1.00 53.41  ? 59  LEU C CD1 1 
ATOM   7285  C CD2 . LEU C 1 38  ? 158.293 178.038 217.799 1.00 53.41  ? 59  LEU C CD2 1 
ATOM   7286  N N   . ASN C 1 39  ? 157.538 173.770 221.587 1.00 75.57  ? 60  ASN C N   1 
ATOM   7287  C CA  . ASN C 1 39  ? 156.779 173.656 222.825 1.00 75.57  ? 60  ASN C CA  1 
ATOM   7288  C C   . ASN C 1 39  ? 157.645 174.086 224.000 1.00 75.57  ? 60  ASN C C   1 
ATOM   7289  O O   . ASN C 1 39  ? 157.132 174.501 225.044 1.00 75.57  ? 60  ASN C O   1 
ATOM   7290  C CB  . ASN C 1 39  ? 156.268 172.228 223.016 1.00 75.57  ? 60  ASN C CB  1 
ATOM   7291  C CG  . ASN C 1 39  ? 155.037 171.934 222.181 1.00 75.57  ? 60  ASN C CG  1 
ATOM   7292  O OD1 . ASN C 1 39  ? 154.182 172.799 221.992 1.00 75.57  ? 60  ASN C OD1 1 
ATOM   7293  N ND2 . ASN C 1 39  ? 154.941 170.710 221.675 1.00 75.57  ? 60  ASN C ND2 1 
ATOM   7294  N N   . ASN C 1 40  ? 158.964 173.978 223.834 1.00 92.24  ? 61  ASN C N   1 
ATOM   7295  C CA  . ASN C 1 40  ? 159.886 174.487 224.842 1.00 92.24  ? 61  ASN C CA  1 
ATOM   7296  C C   . ASN C 1 40  ? 159.915 176.008 224.859 1.00 92.24  ? 61  ASN C C   1 
ATOM   7297  O O   . ASN C 1 40  ? 160.175 176.610 225.907 1.00 92.24  ? 61  ASN C O   1 
ATOM   7298  C CB  . ASN C 1 40  ? 161.287 173.936 224.593 1.00 92.24  ? 61  ASN C CB  1 
ATOM   7299  C CG  . ASN C 1 40  ? 161.396 172.470 224.925 1.00 92.24  ? 61  ASN C CG  1 
ATOM   7300  O OD1 . ASN C 1 40  ? 161.595 171.629 224.049 1.00 92.24  ? 61  ASN C OD1 1 
ATOM   7301  N ND2 . ASN C 1 40  ? 161.262 172.155 226.203 1.00 92.24  ? 61  ASN C ND2 1 
ATOM   7302  N N   . LEU C 1 41  ? 159.651 176.643 223.717 1.00 80.91  ? 62  LEU C N   1 
ATOM   7303  C CA  . LEU C 1 41  ? 159.688 178.094 223.591 1.00 80.91  ? 62  LEU C CA  1 
ATOM   7304  C C   . LEU C 1 41  ? 158.332 178.740 223.837 1.00 80.91  ? 62  LEU C C   1 
ATOM   7305  O O   . LEU C 1 41  ? 158.043 179.800 223.271 1.00 80.91  ? 62  LEU C O   1 
ATOM   7306  C CB  . LEU C 1 41  ? 160.229 178.504 222.218 1.00 80.91  ? 62  LEU C CB  1 
ATOM   7307  C CG  . LEU C 1 41  ? 161.738 178.485 221.930 1.00 80.91  ? 62  LEU C CG  1 
ATOM   7308  C CD1 . LEU C 1 41  ? 162.333 177.086 221.804 1.00 80.91  ? 62  LEU C CD1 1 
ATOM   7309  C CD2 . LEU C 1 41  ? 162.033 179.306 220.682 1.00 80.91  ? 62  LEU C CD2 1 
ATOM   7310  N N   . THR C 1 42  ? 157.490 178.135 224.673 1.00 87.42  ? 63  THR C N   1 
ATOM   7311  C CA  . THR C 1 42  ? 156.206 178.735 225.010 1.00 87.42  ? 63  THR C CA  1 
ATOM   7312  C C   . THR C 1 42  ? 156.333 179.916 225.965 1.00 87.42  ? 63  THR C C   1 
ATOM   7313  O O   . THR C 1 42  ? 155.342 180.621 226.183 1.00 87.42  ? 63  THR C O   1 
ATOM   7314  C CB  . THR C 1 42  ? 155.273 177.683 225.617 1.00 87.42  ? 63  THR C CB  1 
ATOM   7315  O OG1 . THR C 1 42  ? 153.960 178.237 225.763 1.00 87.42  ? 63  THR C OG1 1 
ATOM   7316  C CG2 . THR C 1 42  ? 155.784 177.233 226.980 1.00 87.42  ? 63  THR C CG2 1 
ATOM   7317  N N   . VAL C 1 43  ? 157.515 180.148 226.536 1.00 94.38  ? 64  VAL C N   1 
ATOM   7318  C CA  . VAL C 1 43  ? 157.704 181.277 227.440 1.00 94.38  ? 64  VAL C CA  1 
ATOM   7319  C C   . VAL C 1 43  ? 158.035 182.544 226.660 1.00 94.38  ? 64  VAL C C   1 
ATOM   7320  O O   . VAL C 1 43  ? 157.386 183.582 226.831 1.00 94.38  ? 64  VAL C O   1 
ATOM   7321  C CB  . VAL C 1 43  ? 158.795 180.950 228.476 1.00 94.38  ? 64  VAL C CB  1 
ATOM   7322  C CG1 . VAL C 1 43  ? 159.080 182.159 229.354 1.00 94.38  ? 64  VAL C CG1 1 
ATOM   7323  C CG2 . VAL C 1 43  ? 158.384 179.752 229.320 1.00 94.38  ? 64  VAL C CG2 1 
ATOM   7324  N N   . CYS C 1 44  ? 159.043 182.482 225.788 1.00 104.45 ? 65  CYS C N   1 
ATOM   7325  C CA  . CYS C 1 44  ? 159.536 183.657 225.064 1.00 104.45 ? 65  CYS C CA  1 
ATOM   7326  C C   . CYS C 1 44  ? 159.666 183.347 223.574 1.00 104.45 ? 65  CYS C C   1 
ATOM   7327  O O   . CYS C 1 44  ? 160.763 183.063 223.085 1.00 104.45 ? 65  CYS C O   1 
ATOM   7328  C CB  . CYS C 1 44  ? 160.867 184.119 225.647 1.00 104.45 ? 65  CYS C CB  1 
ATOM   7329  S SG  . CYS C 1 44  ? 160.748 184.973 227.230 1.00 104.45 ? 65  CYS C SG  1 
ATOM   7330  N N   . SER C 1 45  ? 158.548 183.413 222.853 1.00 98.93  ? 66  SER C N   1 
ATOM   7331  C CA  . SER C 1 45  ? 158.581 183.391 221.395 1.00 98.93  ? 66  SER C CA  1 
ATOM   7332  C C   . SER C 1 45  ? 157.678 184.428 220.751 1.00 98.93  ? 66  SER C C   1 
ATOM   7333  O O   . SER C 1 45  ? 157.823 184.663 219.546 1.00 98.93  ? 66  SER C O   1 
ATOM   7334  C CB  . SER C 1 45  ? 158.196 182.006 220.861 1.00 98.93  ? 66  SER C CB  1 
ATOM   7335  O OG  . SER C 1 45  ? 157.073 181.488 221.553 1.00 98.93  ? 66  SER C OG  1 
ATOM   7336  N N   . GLU C 1 46  ? 156.766 185.043 221.502 1.00 92.85  ? 67  GLU C N   1 
ATOM   7337  C CA  . GLU C 1 46  ? 155.734 185.999 221.065 1.00 92.85  ? 67  GLU C CA  1 
ATOM   7338  C C   . GLU C 1 46  ? 154.871 185.335 219.987 1.00 92.85  ? 67  GLU C C   1 
ATOM   7339  O O   . GLU C 1 46  ? 154.657 184.116 220.006 1.00 92.85  ? 67  GLU C O   1 
ATOM   7340  C CB  . GLU C 1 46  ? 156.368 187.322 220.651 1.00 92.85  ? 67  GLU C CB  1 
ATOM   7341  C CG  . GLU C 1 46  ? 156.646 188.269 221.809 1.00 92.85  ? 67  GLU C CG  1 
ATOM   7342  C CD  . GLU C 1 46  ? 158.016 188.064 222.423 1.00 92.85  ? 67  GLU C CD  1 
ATOM   7343  O OE1 . GLU C 1 46  ? 158.806 187.271 221.870 1.00 92.85  ? 67  GLU C OE1 1 
ATOM   7344  O OE2 . GLU C 1 46  ? 158.303 188.699 223.460 1.00 92.85  ? 67  GLU C OE2 1 
ATOM   7345  N N   . MET C 1 47  ? 154.358 186.127 219.051 1.00 96.10  ? 68  MET C N   1 
ATOM   7346  C CA  . MET C 1 47  ? 153.542 185.634 217.949 1.00 96.10  ? 68  MET C CA  1 
ATOM   7347  C C   . MET C 1 47  ? 154.279 185.770 216.621 1.00 96.10  ? 68  MET C C   1 
ATOM   7348  O O   . MET C 1 47  ? 153.696 186.137 215.600 1.00 96.10  ? 68  MET C O   1 
ATOM   7349  C CB  . MET C 1 47  ? 152.204 186.365 217.902 1.00 96.10  ? 68  MET C CB  1 
ATOM   7350  C CG  . MET C 1 47  ? 151.182 185.837 218.893 1.00 96.10  ? 68  MET C CG  1 
ATOM   7351  S SD  . MET C 1 47  ? 149.493 185.945 218.277 1.00 96.10  ? 68  MET C SD  1 
ATOM   7352  C CE  . MET C 1 47  ? 148.572 185.903 219.813 1.00 96.10  ? 68  MET C CE  1 
ATOM   7353  N N   . SER C 1 48  ? 155.581 185.470 216.626 1.00 77.93  ? 69  SER C N   1 
ATOM   7354  C CA  . SER C 1 48  ? 156.407 185.602 215.431 1.00 77.93  ? 69  SER C CA  1 
ATOM   7355  C C   . SER C 1 48  ? 156.140 184.518 214.395 1.00 77.93  ? 69  SER C C   1 
ATOM   7356  O O   . SER C 1 48  ? 156.610 184.645 213.260 1.00 77.93  ? 69  SER C O   1 
ATOM   7357  C CB  . SER C 1 48  ? 157.886 185.589 215.817 1.00 77.93  ? 69  SER C CB  1 
ATOM   7358  O OG  . SER C 1 48  ? 158.213 186.712 216.617 1.00 77.93  ? 69  SER C OG  1 
ATOM   7359  N N   . ILE C 1 49  ? 155.406 183.463 214.752 1.00 55.50  ? 70  ILE C N   1 
ATOM   7360  C CA  . ILE C 1 49  ? 155.059 182.425 213.788 1.00 55.50  ? 70  ILE C CA  1 
ATOM   7361  C C   . ILE C 1 49  ? 153.954 182.898 212.842 1.00 55.50  ? 70  ILE C C   1 
ATOM   7362  O O   . ILE C 1 49  ? 153.799 182.338 211.748 1.00 55.50  ? 70  ILE C O   1 
ATOM   7363  C CB  . ILE C 1 49  ? 154.668 181.143 214.550 1.00 55.50  ? 70  ILE C CB  1 
ATOM   7364  C CG1 . ILE C 1 49  ? 155.640 180.893 215.707 1.00 55.50  ? 70  ILE C CG1 1 
ATOM   7365  C CG2 . ILE C 1 49  ? 154.694 179.905 213.650 1.00 55.50  ? 70  ILE C CG2 1 
ATOM   7366  C CD1 . ILE C 1 49  ? 157.070 180.576 215.276 1.00 55.50  ? 70  ILE C CD1 1 
ATOM   7367  N N   . ASP C 1 50  ? 153.211 183.946 213.221 1.00 52.12  ? 71  ASP C N   1 
ATOM   7368  C CA  . ASP C 1 50  ? 152.074 184.408 212.426 1.00 52.12  ? 71  ASP C CA  1 
ATOM   7369  C C   . ASP C 1 50  ? 152.518 185.030 211.104 1.00 52.12  ? 71  ASP C C   1 
ATOM   7370  O O   . ASP C 1 50  ? 151.837 184.874 210.082 1.00 52.12  ? 71  ASP C O   1 
ATOM   7371  C CB  . ASP C 1 50  ? 151.248 185.407 213.234 1.00 52.12  ? 71  ASP C CB  1 
ATOM   7372  C CG  . ASP C 1 50  ? 149.943 185.766 212.557 1.00 52.12  ? 71  ASP C CG  1 
ATOM   7373  O OD1 . ASP C 1 50  ? 149.012 184.934 212.583 1.00 52.12  ? 71  ASP C OD1 1 
ATOM   7374  O OD2 . ASP C 1 50  ? 149.848 186.878 211.996 1.00 52.12  ? 71  ASP C OD2 1 
ATOM   7375  N N   . GLY C 1 51  ? 153.654 185.731 211.103 1.00 37.96  ? 72  GLY C N   1 
ATOM   7376  C CA  . GLY C 1 51  ? 154.192 186.252 209.854 1.00 37.96  ? 72  GLY C CA  1 
ATOM   7377  C C   . GLY C 1 51  ? 154.653 185.154 208.915 1.00 37.96  ? 72  GLY C C   1 
ATOM   7378  O O   . GLY C 1 51  ? 154.461 185.244 207.698 1.00 37.96  ? 72  GLY C O   1 
ATOM   7379  N N   . TYR C 1 52  ? 155.242 184.091 209.470 1.00 31.93  ? 73  TYR C N   1 
ATOM   7380  C CA  . TYR C 1 52  ? 155.617 182.926 208.673 1.00 31.93  ? 73  TYR C CA  1 
ATOM   7381  C C   . TYR C 1 52  ? 154.388 182.219 208.110 1.00 31.93  ? 73  TYR C C   1 
ATOM   7382  O O   . TYR C 1 52  ? 154.405 181.755 206.963 1.00 31.93  ? 73  TYR C O   1 
ATOM   7383  C CB  . TYR C 1 52  ? 156.451 181.969 209.525 1.00 31.93  ? 73  TYR C CB  1 
ATOM   7384  C CG  . TYR C 1 52  ? 157.056 180.815 208.763 1.00 31.93  ? 73  TYR C CG  1 
ATOM   7385  C CD1 . TYR C 1 52  ? 157.925 181.036 207.703 1.00 31.93  ? 73  TYR C CD1 1 
ATOM   7386  C CD2 . TYR C 1 52  ? 156.763 179.501 209.110 1.00 31.93  ? 73  TYR C CD2 1 
ATOM   7387  C CE1 . TYR C 1 52  ? 158.483 179.979 207.006 1.00 31.93  ? 73  TYR C CE1 1 
ATOM   7388  C CE2 . TYR C 1 52  ? 157.315 178.439 208.419 1.00 31.93  ? 73  TYR C CE2 1 
ATOM   7389  C CZ  . TYR C 1 52  ? 158.174 178.685 207.369 1.00 31.93  ? 73  TYR C CZ  1 
ATOM   7390  O OH  . TYR C 1 52  ? 158.725 177.632 206.680 1.00 31.93  ? 73  TYR C OH  1 
ATOM   7391  N N   . LEU C 1 53  ? 153.313 182.139 208.904 1.00 29.54  ? 74  LEU C N   1 
ATOM   7392  C CA  . LEU C 1 53  ? 152.061 181.552 208.434 1.00 29.54  ? 74  LEU C CA  1 
ATOM   7393  C C   . LEU C 1 53  ? 151.445 182.374 207.308 1.00 29.54  ? 74  LEU C C   1 
ATOM   7394  O O   . LEU C 1 53  ? 150.962 181.815 206.316 1.00 29.54  ? 74  LEU C O   1 
ATOM   7395  C CB  . LEU C 1 53  ? 151.073 181.422 209.592 1.00 29.54  ? 74  LEU C CB  1 
ATOM   7396  C CG  . LEU C 1 53  ? 151.350 180.344 210.638 1.00 29.54  ? 74  LEU C CG  1 
ATOM   7397  C CD1 . LEU C 1 53  ? 150.393 180.482 211.809 1.00 29.54  ? 74  LEU C CD1 1 
ATOM   7398  C CD2 . LEU C 1 53  ? 151.235 178.969 210.015 1.00 29.54  ? 74  LEU C CD2 1 
ATOM   7399  N N   . ASN C 1 54  ? 151.465 183.703 207.439 1.00 31.50  ? 75  ASN C N   1 
ATOM   7400  C CA  . ASN C 1 54  ? 150.943 184.562 206.379 1.00 31.50  ? 75  ASN C CA  1 
ATOM   7401  C C   . ASN C 1 54  ? 151.835 184.543 205.144 1.00 31.50  ? 75  ASN C C   1 
ATOM   7402  O O   . ASN C 1 54  ? 151.359 184.807 204.035 1.00 31.50  ? 75  ASN C O   1 
ATOM   7403  C CB  . ASN C 1 54  ? 150.780 185.991 206.893 1.00 31.50  ? 75  ASN C CB  1 
ATOM   7404  C CG  . ASN C 1 54  ? 149.426 186.228 207.530 1.00 31.50  ? 75  ASN C CG  1 
ATOM   7405  O OD1 . ASN C 1 54  ? 148.552 185.363 207.495 1.00 31.50  ? 75  ASN C OD1 1 
ATOM   7406  N ND2 . ASN C 1 54  ? 149.247 187.405 208.118 1.00 31.50  ? 75  ASN C ND2 1 
ATOM   7407  N N   . LEU C 1 55  ? 153.125 184.243 205.314 1.00 24.52  ? 76  LEU C N   1 
ATOM   7408  C CA  . LEU C 1 55  ? 154.004 184.103 204.159 1.00 24.52  ? 76  LEU C CA  1 
ATOM   7409  C C   . LEU C 1 55  ? 153.756 182.790 203.422 1.00 24.52  ? 76  LEU C C   1 
ATOM   7410  O O   . LEU C 1 55  ? 153.773 182.756 202.187 1.00 24.52  ? 76  LEU C O   1 
ATOM   7411  C CB  . LEU C 1 55  ? 155.463 184.208 204.597 1.00 24.52  ? 76  LEU C CB  1 
ATOM   7412  C CG  . LEU C 1 55  ? 156.030 185.626 204.665 1.00 24.52  ? 76  LEU C CG  1 
ATOM   7413  C CD1 . LEU C 1 55  ? 157.439 185.616 205.234 1.00 24.52  ? 76  LEU C CD1 1 
ATOM   7414  C CD2 . LEU C 1 55  ? 156.004 186.283 203.295 1.00 24.52  ? 76  LEU C CD2 1 
ATOM   7415  N N   . ILE C 1 56  ? 153.525 181.695 204.158 1.00 23.19  ? 77  ILE C N   1 
ATOM   7416  C CA  . ILE C 1 56  ? 153.343 180.393 203.512 1.00 23.19  ? 77  ILE C CA  1 
ATOM   7417  C C   . ILE C 1 56  ? 151.903 180.113 203.099 1.00 23.19  ? 77  ILE C C   1 
ATOM   7418  O O   . ILE C 1 56  ? 151.660 179.139 202.365 1.00 23.19  ? 77  ILE C O   1 
ATOM   7419  C CB  . ILE C 1 56  ? 153.826 179.233 204.406 1.00 23.19  ? 77  ILE C CB  1 
ATOM   7420  C CG1 . ILE C 1 56  ? 152.943 179.101 205.648 1.00 23.19  ? 77  ILE C CG1 1 
ATOM   7421  C CG2 . ILE C 1 56  ? 155.293 179.409 204.772 1.00 23.19  ? 77  ILE C CG2 1 
ATOM   7422  C CD1 . ILE C 1 56  ? 153.144 177.808 206.402 1.00 23.19  ? 77  ILE C CD1 1 
ATOM   7423  N N   . ASN C 1 57  ? 150.936 180.920 203.548 1.00 23.59  ? 78  ASN C N   1 
ATOM   7424  C CA  . ASN C 1 57  ? 149.562 180.733 203.096 1.00 23.59  ? 78  ASN C CA  1 
ATOM   7425  C C   . ASN C 1 57  ? 149.346 181.230 201.674 1.00 23.59  ? 78  ASN C C   1 
ATOM   7426  O O   . ASN C 1 57  ? 148.350 180.857 201.047 1.00 23.59  ? 78  ASN C O   1 
ATOM   7427  C CB  . ASN C 1 57  ? 148.587 181.429 204.043 1.00 23.59  ? 78  ASN C CB  1 
ATOM   7428  C CG  . ASN C 1 57  ? 148.255 180.587 205.258 1.00 23.59  ? 78  ASN C CG  1 
ATOM   7429  O OD1 . ASN C 1 57  ? 148.091 179.371 205.158 1.00 23.59  ? 78  ASN C OD1 1 
ATOM   7430  N ND2 . ASN C 1 57  ? 148.153 181.230 206.415 1.00 23.59  ? 78  ASN C ND2 1 
ATOM   7431  N N   . ALA C 1 58  ? 150.248 182.061 201.152 1.00 23.99  ? 79  ALA C N   1 
ATOM   7432  C CA  . ALA C 1 58  ? 150.208 182.433 199.745 1.00 23.99  ? 79  ALA C CA  1 
ATOM   7433  C C   . ALA C 1 58  ? 150.832 181.376 198.846 1.00 23.99  ? 79  ALA C C   1 
ATOM   7434  O O   . ALA C 1 58  ? 150.746 181.498 197.619 1.00 23.99  ? 79  ALA C O   1 
ATOM   7435  C CB  . ALA C 1 58  ? 150.915 183.773 199.532 1.00 23.99  ? 79  ALA C CB  1 
ATOM   7436  N N   . VAL C 1 59  ? 151.454 180.353 199.423 1.00 24.11  ? 80  VAL C N   1 
ATOM   7437  C CA  . VAL C 1 59  ? 152.063 179.273 198.664 1.00 24.11  ? 80  VAL C CA  1 
ATOM   7438  C C   . VAL C 1 59  ? 151.246 177.990 198.762 1.00 24.11  ? 80  VAL C C   1 
ATOM   7439  O O   . VAL C 1 59  ? 151.018 177.322 197.753 1.00 24.11  ? 80  VAL C O   1 
ATOM   7440  C CB  . VAL C 1 59  ? 153.514 179.050 199.146 1.00 24.11  ? 80  VAL C CB  1 
ATOM   7441  C CG1 . VAL C 1 59  ? 154.192 177.942 198.355 1.00 24.11  ? 80  VAL C CG1 1 
ATOM   7442  C CG2 . VAL C 1 59  ? 154.307 180.341 199.049 1.00 24.11  ? 80  VAL C CG2 1 
ATOM   7443  N N   . ILE C 1 60  ? 150.793 177.645 199.971 1.00 20.24  ? 81  ILE C N   1 
ATOM   7444  C CA  . ILE C 1 60  ? 150.119 176.365 200.191 1.00 20.24  ? 81  ILE C CA  1 
ATOM   7445  C C   . ILE C 1 60  ? 148.727 176.365 199.556 1.00 20.24  ? 81  ILE C C   1 
ATOM   7446  O O   . ILE C 1 60  ? 148.335 175.398 198.889 1.00 20.24  ? 81  ILE C O   1 
ATOM   7447  C CB  . ILE C 1 60  ? 150.071 176.052 201.700 1.00 20.24  ? 81  ILE C CB  1 
ATOM   7448  C CG1 . ILE C 1 60  ? 151.448 175.600 202.183 1.00 20.24  ? 81  ILE C CG1 1 
ATOM   7449  C CG2 . ILE C 1 60  ? 149.066 174.965 202.023 1.00 20.24  ? 81  ILE C CG2 1 
ATOM   7450  C CD1 . ILE C 1 60  ? 151.553 175.478 203.685 1.00 20.24  ? 81  ILE C CD1 1 
ATOM   7451  N N   . ILE C 1 61  ? 147.977 177.460 199.735 1.00 21.91  ? 82  ILE C N   1 
ATOM   7452  C CA  . ILE C 1 61  ? 146.591 177.518 199.242 1.00 21.91  ? 82  ILE C CA  1 
ATOM   7453  C C   . ILE C 1 61  ? 146.463 177.466 197.715 1.00 21.91  ? 82  ILE C C   1 
ATOM   7454  O O   . ILE C 1 61  ? 145.627 176.689 197.221 1.00 21.91  ? 82  ILE C O   1 
ATOM   7455  C CB  . ILE C 1 61  ? 145.860 178.718 199.874 1.00 21.91  ? 82  ILE C CB  1 
ATOM   7456  C CG1 . ILE C 1 61  ? 145.843 178.585 201.397 1.00 21.91  ? 82  ILE C CG1 1 
ATOM   7457  C CG2 . ILE C 1 61  ? 144.435 178.847 199.354 1.00 21.91  ? 82  ILE C CG2 1 
ATOM   7458  C CD1 . ILE C 1 61  ? 145.334 179.817 202.112 1.00 21.91  ? 82  ILE C CD1 1 
ATOM   7459  N N   . PRO C 1 62  ? 147.234 178.237 196.909 1.00 21.97  ? 83  PRO C N   1 
ATOM   7460  C CA  . PRO C 1 62  ? 147.107 178.061 195.447 1.00 21.97  ? 83  PRO C CA  1 
ATOM   7461  C C   . PRO C 1 62  ? 147.630 176.731 194.929 1.00 21.97  ? 83  PRO C C   1 
ATOM   7462  O O   . PRO C 1 62  ? 147.248 176.329 193.823 1.00 21.97  ? 83  PRO C O   1 
ATOM   7463  C CB  . PRO C 1 62  ? 147.917 179.233 194.874 1.00 21.97  ? 83  PRO C CB  1 
ATOM   7464  C CG  . PRO C 1 62  ? 147.941 180.224 195.951 1.00 21.97  ? 83  PRO C CG  1 
ATOM   7465  C CD  . PRO C 1 62  ? 148.126 179.390 197.165 1.00 21.97  ? 83  PRO C CD  1 
ATOM   7466  N N   . ILE C 1 63  ? 148.493 176.044 195.678 1.00 18.51  ? 84  ILE C N   1 
ATOM   7467  C CA  . ILE C 1 63  ? 148.843 174.671 195.332 1.00 18.51  ? 84  ILE C CA  1 
ATOM   7468  C C   . ILE C 1 63  ? 147.654 173.750 195.582 1.00 18.51  ? 84  ILE C C   1 
ATOM   7469  O O   . ILE C 1 63  ? 147.292 172.930 194.728 1.00 18.51  ? 84  ILE C O   1 
ATOM   7470  C CB  . ILE C 1 63  ? 150.093 174.228 196.119 1.00 18.51  ? 84  ILE C CB  1 
ATOM   7471  C CG1 . ILE C 1 63  ? 151.350 174.859 195.519 1.00 18.51  ? 84  ILE C CG1 1 
ATOM   7472  C CG2 . ILE C 1 63  ? 150.233 172.713 196.148 1.00 18.51  ? 84  ILE C CG2 1 
ATOM   7473  C CD1 . ILE C 1 63  ? 152.620 174.521 196.269 1.00 18.51  ? 84  ILE C CD1 1 
ATOM   7474  N N   . SER C 1 64  ? 146.999 173.916 196.737 1.00 18.87  ? 85  SER C N   1 
ATOM   7475  C CA  . SER C 1 64  ? 145.913 173.027 197.142 1.00 18.87  ? 85  SER C CA  1 
ATOM   7476  C C   . SER C 1 64  ? 144.670 173.195 196.279 1.00 18.87  ? 85  SER C C   1 
ATOM   7477  O O   . SER C 1 64  ? 143.967 172.210 196.030 1.00 18.87  ? 85  SER C O   1 
ATOM   7478  C CB  . SER C 1 64  ? 145.559 173.263 198.609 1.00 18.87  ? 85  SER C CB  1 
ATOM   7479  O OG  . SER C 1 64  ? 144.337 172.629 198.943 1.00 18.87  ? 85  SER C OG  1 
ATOM   7480  N N   . GLN C 1 65  ? 144.391 174.420 195.814 1.00 23.73  ? 86  GLN C N   1 
ATOM   7481  C CA  . GLN C 1 65  ? 143.226 174.660 194.960 1.00 23.73  ? 86  GLN C CA  1 
ATOM   7482  C C   . GLN C 1 65  ? 143.352 173.937 193.623 1.00 23.73  ? 86  GLN C C   1 
ATOM   7483  O O   . GLN C 1 65  ? 142.424 173.240 193.194 1.00 23.73  ? 86  GLN C O   1 
ATOM   7484  C CB  . GLN C 1 65  ? 143.035 176.160 194.737 1.00 23.73  ? 86  GLN C CB  1 
ATOM   7485  C CG  . GLN C 1 65  ? 142.467 176.902 195.931 1.00 23.73  ? 86  GLN C CG  1 
ATOM   7486  C CD  . GLN C 1 65  ? 141.082 176.418 196.306 1.00 23.73  ? 86  GLN C CD  1 
ATOM   7487  O OE1 . GLN C 1 65  ? 140.896 175.768 197.334 1.00 23.73  ? 86  GLN C OE1 1 
ATOM   7488  N NE2 . GLN C 1 65  ? 140.100 176.735 195.472 1.00 23.73  ? 86  GLN C NE2 1 
ATOM   7489  N N   . SER C 1 66  ? 144.508 174.065 192.965 1.00 24.01  ? 87  SER C N   1 
ATOM   7490  C CA  . SER C 1 66  ? 144.734 173.340 191.720 1.00 24.01  ? 87  SER C CA  1 
ATOM   7491  C C   . SER C 1 66  ? 144.853 171.840 191.958 1.00 24.01  ? 87  SER C C   1 
ATOM   7492  O O   . SER C 1 66  ? 144.447 171.047 191.100 1.00 24.01  ? 87  SER C O   1 
ATOM   7493  C CB  . SER C 1 66  ? 145.986 173.868 191.021 1.00 24.01  ? 87  SER C CB  1 
ATOM   7494  O OG  . SER C 1 66  ? 146.383 173.004 189.971 1.00 24.01  ? 87  SER C OG  1 
ATOM   7495  N N   . LEU C 1 67  ? 145.369 171.438 193.126 1.00 24.37  ? 88  LEU C N   1 
ATOM   7496  C CA  . LEU C 1 67  ? 145.515 170.021 193.438 1.00 24.37  ? 88  LEU C CA  1 
ATOM   7497  C C   . LEU C 1 67  ? 144.164 169.344 193.629 1.00 24.37  ? 88  LEU C C   1 
ATOM   7498  O O   . LEU C 1 67  ? 143.984 168.188 193.229 1.00 24.37  ? 88  LEU C O   1 
ATOM   7499  C CB  . LEU C 1 67  ? 146.381 169.861 194.685 1.00 24.37  ? 88  LEU C CB  1 
ATOM   7500  C CG  . LEU C 1 67  ? 147.019 168.498 194.923 1.00 24.37  ? 88  LEU C CG  1 
ATOM   7501  C CD1 . LEU C 1 67  ? 147.785 168.068 193.700 1.00 24.37  ? 88  LEU C CD1 1 
ATOM   7502  C CD2 . LEU C 1 67  ? 147.949 168.588 196.107 1.00 24.37  ? 88  LEU C CD2 1 
ATOM   7503  N N   . GLU C 1 68  ? 143.201 170.039 194.236 1.00 30.77  ? 89  GLU C N   1 
ATOM   7504  C CA  . GLU C 1 68  ? 141.867 169.459 194.342 1.00 30.77  ? 89  GLU C CA  1 
ATOM   7505  C C   . GLU C 1 68  ? 141.050 169.670 193.073 1.00 30.77  ? 89  GLU C C   1 
ATOM   7506  O O   . GLU C 1 68  ? 140.093 168.927 192.836 1.00 30.77  ? 89  GLU C O   1 
ATOM   7507  C CB  . GLU C 1 68  ? 141.122 170.019 195.558 1.00 30.77  ? 89  GLU C CB  1 
ATOM   7508  C CG  . GLU C 1 68  ? 140.822 171.505 195.514 1.00 30.77  ? 89  GLU C CG  1 
ATOM   7509  C CD  . GLU C 1 68  ? 139.418 171.815 195.048 1.00 30.77  ? 89  GLU C CD  1 
ATOM   7510  O OE1 . GLU C 1 68  ? 138.553 170.917 195.115 1.00 30.77  ? 89  GLU C OE1 1 
ATOM   7511  O OE2 . GLU C 1 68  ? 139.184 172.961 194.616 1.00 30.77  ? 89  GLU C OE2 1 
ATOM   7512  N N   . LEU C 1 69  ? 141.397 170.666 192.250 1.00 34.70  ? 90  LEU C N   1 
ATOM   7513  C CA  . LEU C 1 69  ? 140.664 170.855 191.002 1.00 34.70  ? 90  LEU C CA  1 
ATOM   7514  C C   . LEU C 1 69  ? 141.062 169.823 189.954 1.00 34.70  ? 90  LEU C C   1 
ATOM   7515  O O   . LEU C 1 69  ? 140.226 169.427 189.135 1.00 34.70  ? 90  LEU C O   1 
ATOM   7516  C CB  . LEU C 1 69  ? 140.873 172.284 190.485 1.00 34.70  ? 90  LEU C CB  1 
ATOM   7517  C CG  . LEU C 1 69  ? 140.037 172.849 189.326 1.00 34.70  ? 90  LEU C CG  1 
ATOM   7518  C CD1 . LEU C 1 69  ? 139.828 174.335 189.549 1.00 34.70  ? 90  LEU C CD1 1 
ATOM   7519  C CD2 . LEU C 1 69  ? 140.685 172.639 187.960 1.00 34.70  ? 90  LEU C CD2 1 
ATOM   7520  N N   . MET C 1 70  ? 142.326 169.385 189.949 1.00 34.01  ? 91  MET C N   1 
ATOM   7521  C CA  . MET C 1 70  ? 142.735 168.375 188.977 1.00 34.01  ? 91  MET C CA  1 
ATOM   7522  C C   . MET C 1 70  ? 142.184 166.997 189.322 1.00 34.01  ? 91  MET C C   1 
ATOM   7523  O O   . MET C 1 70  ? 142.029 166.156 188.430 1.00 34.01  ? 91  MET C O   1 
ATOM   7524  C CB  . MET C 1 70  ? 144.258 168.326 188.855 1.00 34.01  ? 91  MET C CB  1 
ATOM   7525  C CG  . MET C 1 70  ? 144.862 169.555 188.196 1.00 34.01  ? 91  MET C CG  1 
ATOM   7526  S SD  . MET C 1 70  ? 145.113 169.349 186.423 1.00 34.01  ? 91  MET C SD  1 
ATOM   7527  C CE  . MET C 1 70  ? 146.670 168.467 186.395 1.00 34.01  ? 91  MET C CE  1 
ATOM   7528  N N   . ARG C 1 71  ? 141.889 166.740 190.595 1.00 27.99  ? 92  ARG C N   1 
ATOM   7529  C CA  . ARG C 1 71  ? 141.235 165.495 190.971 1.00 27.99  ? 92  ARG C CA  1 
ATOM   7530  C C   . ARG C 1 71  ? 139.717 165.607 190.996 1.00 27.99  ? 92  ARG C C   1 
ATOM   7531  O O   . ARG C 1 71  ? 139.043 164.603 191.246 1.00 27.99  ? 92  ARG C O   1 
ATOM   7532  C CB  . ARG C 1 71  ? 141.732 165.013 192.339 1.00 27.99  ? 92  ARG C CB  1 
ATOM   7533  C CG  . ARG C 1 71  ? 141.178 165.784 193.523 1.00 27.99  ? 92  ARG C CG  1 
ATOM   7534  C CD  . ARG C 1 71  ? 141.607 165.145 194.837 1.00 27.99  ? 92  ARG C CD  1 
ATOM   7535  N NE  . ARG C 1 71  ? 143.044 165.252 195.059 1.00 27.99  ? 92  ARG C NE  1 
ATOM   7536  C CZ  . ARG C 1 71  ? 143.863 164.216 195.176 1.00 27.99  ? 92  ARG C CZ  1 
ATOM   7537  N NH1 . ARG C 1 71  ? 143.421 162.973 195.095 1.00 27.99  ? 92  ARG C NH1 1 
ATOM   7538  N NH2 . ARG C 1 71  ? 145.159 164.434 195.378 1.00 27.99  ? 92  ARG C NH2 1 
ATOM   7539  N N   . ASN C 1 72  ? 139.167 166.793 190.742 1.00 48.96  ? 93  ASN C N   1 
ATOM   7540  C CA  . ASN C 1 72  ? 137.722 166.968 190.679 1.00 48.96  ? 93  ASN C CA  1 
ATOM   7541  C C   . ASN C 1 72  ? 137.149 166.620 189.315 1.00 48.96  ? 93  ASN C C   1 
ATOM   7542  O O   . ASN C 1 72  ? 135.924 166.565 189.169 1.00 48.96  ? 93  ASN C O   1 
ATOM   7543  C CB  . ASN C 1 72  ? 137.343 168.410 191.025 1.00 48.96  ? 93  ASN C CB  1 
ATOM   7544  C CG  . ASN C 1 72  ? 136.101 168.493 191.883 1.00 48.96  ? 93  ASN C CG  1 
ATOM   7545  O OD1 . ASN C 1 72  ? 135.456 167.477 192.146 1.00 48.96  ? 93  ASN C OD1 1 
ATOM   7546  N ND2 . ASN C 1 72  ? 135.756 169.712 192.316 1.00 48.96  ? 93  ASN C ND2 1 
ATOM   7547  N N   . ASN C 1 73  ? 138.001 166.391 188.319 1.00 49.43  ? 94  ASN C N   1 
ATOM   7548  C CA  . ASN C 1 73  ? 137.543 166.099 186.957 1.00 49.43  ? 94  ASN C CA  1 
ATOM   7549  C C   . ASN C 1 73  ? 137.430 164.593 186.746 1.00 49.43  ? 94  ASN C C   1 
ATOM   7550  O O   . ASN C 1 73  ? 136.462 164.112 186.150 1.00 49.43  ? 94  ASN C O   1 
ATOM   7551  C CB  . ASN C 1 73  ? 138.488 166.732 185.935 1.00 49.43  ? 94  ASN C CB  1 
ATOM   7552  C CG  . ASN C 1 73  ? 138.168 168.185 185.672 1.00 49.43  ? 94  ASN C CG  1 
ATOM   7553  O OD1 . ASN C 1 73  ? 137.056 168.641 185.931 1.00 49.43  ? 94  ASN C OD1 1 
ATOM   7554  N ND2 . ASN C 1 73  ? 139.142 168.923 185.152 1.00 49.43  ? 94  ASN C ND2 1 
ATOM   7555  N N   . VAL C 1 74  ? 138.496 163.858 187.080 1.00 43.62  ? 95  VAL C N   1 
ATOM   7556  C CA  . VAL C 1 74  ? 138.515 162.390 186.779 1.00 43.62  ? 95  VAL C CA  1 
ATOM   7557  C C   . VAL C 1 74  ? 137.416 161.685 187.585 1.00 43.62  ? 95  VAL C C   1 
ATOM   7558  O O   . VAL C 1 74  ? 137.296 161.960 188.791 1.00 43.62  ? 95  VAL C O   1 
ATOM   7559  C CB  . VAL C 1 74  ? 139.888 161.744 187.031 1.00 43.62  ? 95  VAL C CB  1 
ATOM   7560  C CG1 . VAL C 1 74  ? 140.423 162.073 188.418 1.00 43.62  ? 95  VAL C CG1 1 
ATOM   7561  C CG2 . VAL C 1 74  ? 139.856 160.238 186.810 1.00 43.62  ? 95  VAL C CG2 1 
ATOM   7562  N N   . LYS C 1 75  ? 136.651 160.810 186.931 1.00 54.21  ? 96  LYS C N   1 
ATOM   7563  C CA  . LYS C 1 75  ? 135.537 160.110 187.621 1.00 54.21  ? 96  LYS C CA  1 
ATOM   7564  C C   . LYS C 1 75  ? 135.617 158.610 187.309 1.00 54.21  ? 96  LYS C C   1 
ATOM   7565  O O   . LYS C 1 75  ? 136.053 158.264 186.191 1.00 54.21  ? 96  LYS C O   1 
ATOM   7566  C CB  . LYS C 1 75  ? 134.180 160.692 187.218 1.00 54.21  ? 96  LYS C CB  1 
ATOM   7567  C CG  . LYS C 1 75  ? 133.320 161.138 188.391 1.00 54.21  ? 96  LYS C CG  1 
ATOM   7568  C CD  . LYS C 1 75  ? 133.834 160.637 189.735 1.00 54.21  ? 96  LYS C CD  1 
ATOM   7569  C CE  . LYS C 1 75  ? 134.374 161.735 190.596 1.00 54.21  ? 96  LYS C CE  1 
ATOM   7570  N NZ  . LYS C 1 75  ? 135.772 161.493 190.960 1.00 54.21  ? 96  LYS C NZ  1 
ATOM   7571  N N   . ASP C 1 76  ? 135.214 157.764 188.259 1.00 68.57  ? 97  ASP C N   1 
ATOM   7572  C CA  . ASP C 1 76  ? 135.358 156.297 188.069 1.00 68.57  ? 97  ASP C CA  1 
ATOM   7573  C C   . ASP C 1 76  ? 134.018 155.690 187.669 1.00 68.57  ? 97  ASP C C   1 
ATOM   7574  O O   . ASP C 1 76  ? 133.002 156.408 187.731 1.00 68.57  ? 97  ASP C O   1 
ATOM   7575  C CB  . ASP C 1 76  ? 135.870 155.629 189.330 1.00 68.57  ? 97  ASP C CB  1 
ATOM   7576  C CG  . ASP C 1 76  ? 134.823 155.440 190.415 1.00 68.57  ? 97  ASP C CG  1 
ATOM   7577  O OD1 . ASP C 1 76  ? 134.178 156.443 190.781 1.00 68.57  ? 97  ASP C OD1 1 
ATOM   7578  O OD2 . ASP C 1 76  ? 134.655 154.292 190.871 1.00 68.57  ? 97  ASP C OD2 1 
ATOM   7579  N N   . GLY C 1 77  ? 134.026 154.413 187.285 1.00 91.15  ? 98  GLY C N   1 
ATOM   7580  C CA  . GLY C 1 77  ? 132.785 153.724 186.884 1.00 91.15  ? 98  GLY C CA  1 
ATOM   7581  C C   . GLY C 1 77  ? 132.545 153.865 185.396 1.00 91.15  ? 98  GLY C C   1 
ATOM   7582  O O   . GLY C 1 77  ? 131.683 154.679 185.015 1.00 91.15  ? 98  GLY C O   1 
ATOM   7583  N N   . THR C 1 78  ? 133.271 153.097 184.579 1.00 101.31 ? 99  THR C N   1 
ATOM   7584  C CA  . THR C 1 78  ? 133.146 153.249 183.114 1.00 101.31 ? 99  THR C CA  1 
ATOM   7585  C C   . THR C 1 78  ? 131.711 152.995 182.719 1.00 101.31 ? 99  THR C C   1 
ATOM   7586  O O   . THR C 1 78  ? 131.138 151.984 183.177 1.00 101.31 ? 99  THR C O   1 
ATOM   7587  C CB  . THR C 1 78  ? 134.114 152.313 182.393 1.00 101.31 ? 99  THR C CB  1 
ATOM   7588  O OG1 . THR C 1 78  ? 135.408 152.744 182.799 1.00 101.31 ? 99  THR C OG1 1 
ATOM   7589  C CG2 . THR C 1 78  ? 134.003 152.400 180.882 1.00 101.31 ? 99  THR C CG2 1 
ATOM   7590  N N   . PRO C 1 79  ? 131.097 153.851 181.875 1.00 108.37 ? 100 PRO C N   1 
ATOM   7591  C CA  . PRO C 1 79  ? 129.664 153.722 181.495 1.00 108.37 ? 100 PRO C CA  1 
ATOM   7592  C C   . PRO C 1 79  ? 129.410 152.356 180.882 1.00 108.37 ? 100 PRO C C   1 
ATOM   7593  O O   . PRO C 1 79  ? 128.297 151.806 181.031 1.00 108.37 ? 100 PRO C O   1 
ATOM   7594  C CB  . PRO C 1 79  ? 129.442 154.845 180.491 1.00 108.37 ? 100 PRO C CB  1 
ATOM   7595  C CG  . PRO C 1 79  ? 130.835 155.167 179.983 1.00 108.37 ? 100 PRO C CG  1 
ATOM   7596  C CD  . PRO C 1 79  ? 131.714 155.022 181.179 1.00 108.37 ? 100 PRO C CD  1 
ATOM   7597  N N   . ASN C 1 80  ? 130.425 151.815 180.211 1.00 111.95 ? 101 ASN C N   1 
ATOM   7598  C CA  . ASN C 1 80  ? 130.276 150.467 179.610 1.00 111.95 ? 101 ASN C CA  1 
ATOM   7599  C C   . ASN C 1 80  ? 129.655 149.536 180.649 1.00 111.95 ? 101 ASN C C   1 
ATOM   7600  O O   . ASN C 1 80  ? 130.163 149.489 181.789 1.00 111.95 ? 101 ASN C O   1 
ATOM   7601  C CB  . ASN C 1 80  ? 131.612 149.904 179.156 1.00 111.95 ? 101 ASN C CB  1 
ATOM   7602  C CG  . ASN C 1 80  ? 132.337 150.855 178.239 1.00 111.95 ? 101 ASN C CG  1 
ATOM   7603  O OD1 . ASN C 1 80  ? 132.038 152.054 178.221 1.00 111.95 ? 101 ASN C OD1 1 
ATOM   7604  N ND2 . ASN C 1 80  ? 133.279 150.336 177.467 1.00 111.95 ? 101 ASN C ND2 1 
ATOM   7605  N N   . GLU C 1 81  ? 128.611 148.808 180.257 1.00 116.42 ? 102 GLU C N   1 
ATOM   7606  C CA  . GLU C 1 81  ? 127.952 147.861 181.188 1.00 116.42 ? 102 GLU C CA  1 
ATOM   7607  C C   . GLU C 1 81  ? 128.997 146.856 181.686 1.00 116.42 ? 102 GLU C C   1 
ATOM   7608  O O   . GLU C 1 81  ? 128.814 146.309 182.792 1.00 116.42 ? 102 GLU C O   1 
ATOM   7609  C CB  . GLU C 1 81  ? 126.801 147.163 180.466 1.00 116.42 ? 102 GLU C CB  1 
ATOM   7610  C CG  . GLU C 1 81  ? 127.223 145.904 179.712 1.00 116.42 ? 102 GLU C CG  1 
ATOM   7611  C CD  . GLU C 1 81  ? 127.911 146.135 178.378 1.00 116.42 ? 102 GLU C CD  1 
ATOM   7612  O OE1 . GLU C 1 81  ? 128.392 147.261 178.127 1.00 116.42 ? 102 GLU C OE1 1 
ATOM   7613  O OE2 . GLU C 1 81  ? 127.971 145.172 177.585 1.00 116.42 ? 102 GLU C OE2 1 
ATOM   7614  N N   . ASN C 1 82  ? 130.050 146.628 180.900 1.00 112.89 ? 103 ASN C N   1 
ATOM   7615  C CA  . ASN C 1 82  ? 131.086 145.632 181.279 1.00 112.89 ? 103 ASN C CA  1 
ATOM   7616  C C   . ASN C 1 82  ? 132.376 146.357 181.666 1.00 112.89 ? 103 ASN C C   1 
ATOM   7617  O O   . ASN C 1 82  ? 132.824 146.194 182.819 1.00 112.89 ? 103 ASN C O   1 
ATOM   7618  C CB  . ASN C 1 82  ? 131.332 144.645 180.146 1.00 112.89 ? 103 ASN C CB  1 
ATOM   7619  C CG  . ASN C 1 82  ? 131.189 145.288 178.786 1.00 112.89 ? 103 ASN C CG  1 
ATOM   7620  O OD1 . ASN C 1 82  ? 131.342 146.507 178.652 1.00 112.89 ? 103 ASN C OD1 1 
ATOM   7621  N ND2 . ASN C 1 82  ? 130.897 144.491 177.769 1.00 112.89 ? 103 ASN C ND2 1 
ATOM   7622  N N   . ILE C 1 83  ? 132.948 147.126 180.737 1.00 108.73 ? 104 ILE C N   1 
ATOM   7623  C CA  . ILE C 1 83  ? 134.249 147.807 181.008 1.00 108.73 ? 104 ILE C CA  1 
ATOM   7624  C C   . ILE C 1 83  ? 134.054 148.791 182.166 1.00 108.73 ? 104 ILE C C   1 
ATOM   7625  O O   . ILE C 1 83  ? 133.028 149.500 182.171 1.00 108.73 ? 104 ILE C O   1 
ATOM   7626  C CB  . ILE C 1 83  ? 134.769 148.515 179.747 1.00 108.73 ? 104 ILE C CB  1 
ATOM   7627  C CG1 . ILE C 1 83  ? 134.963 147.534 178.591 1.00 108.73 ? 104 ILE C CG1 1 
ATOM   7628  C CG2 . ILE C 1 83  ? 136.047 149.299 180.046 1.00 108.73 ? 104 ILE C CG2 1 
ATOM   7629  C CD1 . ILE C 1 83  ? 135.761 148.096 177.428 1.00 108.73 ? 104 ILE C CD1 1 
ATOM   7630  N N   . PHE C 1 84  ? 134.998 148.809 183.105 1.00 101.86 ? 105 PHE C N   1 
ATOM   7631  C CA  . PHE C 1 84  ? 134.919 149.759 184.245 1.00 101.86 ? 105 PHE C CA  1 
ATOM   7632  C C   . PHE C 1 84  ? 136.320 150.284 184.516 1.00 101.86 ? 105 PHE C C   1 
ATOM   7633  O O   . PHE C 1 84  ? 137.299 149.550 184.271 1.00 101.86 ? 105 PHE C O   1 
ATOM   7634  C CB  . PHE C 1 84  ? 134.260 149.082 185.450 1.00 101.86 ? 105 PHE C CB  1 
ATOM   7635  C CG  . PHE C 1 84  ? 132.750 149.277 185.475 1.00 101.86 ? 105 PHE C CG  1 
ATOM   7636  C CD1 . PHE C 1 84  ? 132.186 150.411 186.045 1.00 101.86 ? 105 PHE C CD1 1 
ATOM   7637  C CD2 . PHE C 1 84  ? 131.898 148.335 184.909 1.00 101.86 ? 105 PHE C CD2 1 
ATOM   7638  C CE1 . PHE C 1 84  ? 130.813 150.592 186.058 1.00 101.86 ? 105 PHE C CE1 1 
ATOM   7639  C CE2 . PHE C 1 84  ? 130.525 148.522 184.923 1.00 101.86 ? 105 PHE C CE2 1 
ATOM   7640  C CZ  . PHE C 1 84  ? 129.985 149.648 185.497 1.00 101.86 ? 105 PHE C CZ  1 
ATOM   7641  N N   . GLY C 1 85  ? 136.415 151.528 184.988 1.00 78.99  ? 106 GLY C N   1 
ATOM   7642  C CA  . GLY C 1 85  ? 137.730 152.142 185.242 1.00 78.99  ? 106 GLY C CA  1 
ATOM   7643  C C   . GLY C 1 85  ? 137.578 153.621 185.511 1.00 78.99  ? 106 GLY C C   1 
ATOM   7644  O O   . GLY C 1 85  ? 136.489 154.032 185.958 1.00 78.99  ? 106 GLY C O   1 
ATOM   7645  N N   . ALA C 1 86  ? 138.627 154.396 185.246 1.00 61.27  ? 107 ALA C N   1 
ATOM   7646  C CA  . ALA C 1 86  ? 138.585 155.847 185.527 1.00 61.27  ? 107 ALA C CA  1 
ATOM   7647  C C   . ALA C 1 86  ? 138.407 156.605 184.213 1.00 61.27  ? 107 ALA C C   1 
ATOM   7648  O O   . ALA C 1 86  ? 139.033 156.211 183.211 1.00 61.27  ? 107 ALA C O   1 
ATOM   7649  C CB  . ALA C 1 86  ? 139.856 156.247 186.230 1.00 61.27  ? 107 ALA C CB  1 
ATOM   7650  N N   . ILE C 1 87  ? 137.586 157.659 184.219 1.00 53.51  ? 108 ILE C N   1 
ATOM   7651  C CA  . ILE C 1 87  ? 137.400 158.482 182.988 1.00 53.51  ? 108 ILE C CA  1 
ATOM   7652  C C   . ILE C 1 87  ? 137.866 159.921 183.261 1.00 53.51  ? 108 ILE C C   1 
ATOM   7653  O O   . ILE C 1 87  ? 137.493 160.461 184.321 1.00 53.51  ? 108 ILE C O   1 
ATOM   7654  C CB  . ILE C 1 87  ? 135.938 158.429 182.515 1.00 53.51  ? 108 ILE C CB  1 
ATOM   7655  C CG1 . ILE C 1 87  ? 135.337 157.038 182.699 1.00 53.51  ? 108 ILE C CG1 1 
ATOM   7656  C CG2 . ILE C 1 87  ? 135.823 158.902 181.067 1.00 53.51  ? 108 ILE C CG2 1 
ATOM   7657  C CD1 . ILE C 1 87  ? 134.068 157.019 183.529 1.00 53.51  ? 108 ILE C CD1 1 
ATOM   7658  N N   . VAL C 1 88  ? 138.671 160.495 182.359 1.00 43.98  ? 109 VAL C N   1 
ATOM   7659  C CA  . VAL C 1 88  ? 139.127 161.910 182.496 1.00 43.98  ? 109 VAL C CA  1 
ATOM   7660  C C   . VAL C 1 88  ? 138.215 162.764 181.611 1.00 43.98  ? 109 VAL C C   1 
ATOM   7661  O O   . VAL C 1 88  ? 138.175 162.512 180.393 1.00 43.98  ? 109 VAL C O   1 
ATOM   7662  C CB  . VAL C 1 88  ? 140.604 162.087 182.107 1.00 43.98  ? 109 VAL C CB  1 
ATOM   7663  C CG1 . VAL C 1 88  ? 141.532 161.682 183.242 1.00 43.98  ? 109 VAL C CG1 1 
ATOM   7664  C CG2 . VAL C 1 88  ? 140.960 161.333 180.834 1.00 43.98  ? 109 VAL C CG2 1 
ATOM   7665  N N   . ALA C 1 89  ? 137.496 163.716 182.198 1.00 42.52  ? 110 ALA C N   1 
ATOM   7666  C CA  . ALA C 1 89  ? 136.540 164.500 181.427 1.00 42.52  ? 110 ALA C CA  1 
ATOM   7667  C C   . ALA C 1 89  ? 137.255 165.585 180.634 1.00 42.52  ? 110 ALA C C   1 
ATOM   7668  O O   . ALA C 1 89  ? 137.562 166.652 181.175 1.00 42.52  ? 110 ALA C O   1 
ATOM   7669  C CB  . ALA C 1 89  ? 135.481 165.113 182.343 1.00 42.52  ? 110 ALA C CB  1 
ATOM   7670  N N   . GLY C 1 90  ? 137.516 165.316 179.355 1.00 36.41  ? 111 GLY C N   1 
ATOM   7671  C CA  . GLY C 1 90  ? 138.279 166.194 178.485 1.00 36.41  ? 111 GLY C CA  1 
ATOM   7672  C C   . GLY C 1 90  ? 137.701 167.574 178.246 1.00 36.41  ? 111 GLY C C   1 
ATOM   7673  O O   . GLY C 1 90  ? 138.434 168.504 177.899 1.00 36.41  ? 111 GLY C O   1 
ATOM   7674  N N   . ALA C 1 91  ? 136.386 167.717 178.416 1.00 41.56  ? 112 ALA C N   1 
ATOM   7675  C CA  . ALA C 1 91  ? 135.713 168.998 178.234 1.00 41.56  ? 112 ALA C CA  1 
ATOM   7676  C C   . ALA C 1 91  ? 136.099 170.007 179.310 1.00 41.56  ? 112 ALA C C   1 
ATOM   7677  O O   . ALA C 1 91  ? 136.011 171.219 179.088 1.00 41.56  ? 112 ALA C O   1 
ATOM   7678  C CB  . ALA C 1 91  ? 134.196 168.802 178.220 1.00 41.56  ? 112 ALA C CB  1 
ATOM   7679  N N   . ALA C 1 92  ? 136.528 169.524 180.478 1.00 37.73  ? 113 ALA C N   1 
ATOM   7680  C CA  . ALA C 1 92  ? 136.923 170.398 181.571 1.00 37.73  ? 113 ALA C CA  1 
ATOM   7681  C C   . ALA C 1 92  ? 138.429 170.551 181.729 1.00 37.73  ? 113 ALA C C   1 
ATOM   7682  O O   . ALA C 1 92  ? 138.867 171.501 182.384 1.00 37.73  ? 113 ALA C O   1 
ATOM   7683  C CB  . ALA C 1 92  ? 136.336 169.894 182.897 1.00 37.73  ? 113 ALA C CB  1 
ATOM   7684  N N   . LEU C 1 93  ? 139.227 169.646 181.156 1.00 44.13  ? 114 LEU C N   1 
ATOM   7685  C CA  . LEU C 1 93  ? 140.678 169.800 181.220 1.00 44.13  ? 114 LEU C CA  1 
ATOM   7686  C C   . LEU C 1 93  ? 141.168 170.917 180.310 1.00 44.13  ? 114 LEU C C   1 
ATOM   7687  O O   . LEU C 1 93  ? 142.088 171.655 180.679 1.00 44.13  ? 114 LEU C O   1 
ATOM   7688  C CB  . LEU C 1 93  ? 141.381 168.490 180.858 1.00 44.13  ? 114 LEU C CB  1 
ATOM   7689  C CG  . LEU C 1 93  ? 141.739 167.472 181.950 1.00 44.13  ? 114 LEU C CG  1 
ATOM   7690  C CD1 . LEU C 1 93  ? 142.737 168.078 182.927 1.00 44.13  ? 114 LEU C CD1 1 
ATOM   7691  C CD2 . LEU C 1 93  ? 140.524 166.935 182.691 1.00 44.13  ? 114 LEU C CD2 1 
ATOM   7692  N N   . GLY C 1 94  ? 140.574 171.062 179.130 1.00 34.24  ? 115 GLY C N   1 
ATOM   7693  C CA  . GLY C 1 94  ? 141.009 172.088 178.206 1.00 34.24  ? 115 GLY C CA  1 
ATOM   7694  C C   . GLY C 1 94  ? 142.119 171.617 177.292 1.00 34.24  ? 115 GLY C C   1 
ATOM   7695  O O   . GLY C 1 94  ? 141.860 170.983 176.267 1.00 34.24  ? 115 GLY C O   1 
ATOM   7696  N N   . ILE C 1 95  ? 143.362 171.945 177.639 1.00 29.27  ? 116 ILE C N   1 
ATOM   7697  C CA  . ILE C 1 95  ? 144.538 171.546 176.874 1.00 29.27  ? 116 ILE C CA  1 
ATOM   7698  C C   . ILE C 1 95  ? 145.466 170.769 177.798 1.00 29.27  ? 116 ILE C C   1 
ATOM   7699  O O   . ILE C 1 95  ? 145.875 171.281 178.845 1.00 29.27  ? 116 ILE C O   1 
ATOM   7700  C CB  . ILE C 1 95  ? 145.263 172.762 176.270 1.00 29.27  ? 116 ILE C CB  1 
ATOM   7701  C CG1 . ILE C 1 95  ? 144.300 173.601 175.426 1.00 29.27  ? 116 ILE C CG1 1 
ATOM   7702  C CG2 . ILE C 1 95  ? 146.451 172.313 175.436 1.00 29.27  ? 116 ILE C CG2 1 
ATOM   7703  C CD1 . ILE C 1 95  ? 144.792 174.994 175.134 1.00 29.27  ? 116 ILE C CD1 1 
ATOM   7704  N N   . ALA C 1 96  ? 145.802 169.540 177.407 1.00 30.41  ? 117 ALA C N   1 
ATOM   7705  C CA  . ALA C 1 96  ? 146.638 168.687 178.238 1.00 30.41  ? 117 ALA C CA  1 
ATOM   7706  C C   . ALA C 1 96  ? 147.425 167.724 177.362 1.00 30.41  ? 117 ALA C C   1 
ATOM   7707  O O   . ALA C 1 96  ? 147.043 167.426 176.228 1.00 30.41  ? 117 ALA C O   1 
ATOM   7708  C CB  . ALA C 1 96  ? 145.803 167.908 179.261 1.00 30.41  ? 117 ALA C CB  1 
ATOM   7709  N N   . THR C 1 97  ? 148.534 167.236 177.911 1.00 35.20  ? 118 THR C N   1 
ATOM   7710  C CA  . THR C 1 97  ? 149.387 166.259 177.257 1.00 35.20  ? 118 THR C CA  1 
ATOM   7711  C C   . THR C 1 97  ? 149.124 164.874 177.846 1.00 35.20  ? 118 THR C C   1 
ATOM   7712  O O   . THR C 1 97  ? 148.197 164.677 178.636 1.00 35.20  ? 118 THR C O   1 
ATOM   7713  C CB  . THR C 1 97  ? 150.856 166.664 177.392 1.00 35.20  ? 118 THR C CB  1 
ATOM   7714  O OG1 . THR C 1 97  ? 151.299 166.424 178.733 1.00 35.20  ? 118 THR C OG1 1 
ATOM   7715  C CG2 . THR C 1 97  ? 151.034 168.137 177.063 1.00 35.20  ? 118 THR C CG2 1 
ATOM   7716  N N   . ALA C 1 98  ? 149.945 163.896 177.454 1.00 35.20  ? 119 ALA C N   1 
ATOM   7717  C CA  . ALA C 1 98  ? 149.753 162.528 177.927 1.00 35.20  ? 119 ALA C CA  1 
ATOM   7718  C C   . ALA C 1 98  ? 150.180 162.369 179.382 1.00 35.20  ? 119 ALA C C   1 
ATOM   7719  O O   . ALA C 1 98  ? 149.498 161.693 180.167 1.00 35.20  ? 119 ALA C O   1 
ATOM   7720  C CB  . ALA C 1 98  ? 150.526 161.557 177.038 1.00 35.20  ? 119 ALA C CB  1 
ATOM   7721  N N   . ALA C 1 99  ? 151.308 162.983 179.757 1.00 32.46  ? 120 ALA C N   1 
ATOM   7722  C CA  . ALA C 1 99  ? 151.832 162.839 181.112 1.00 32.46  ? 120 ALA C CA  1 
ATOM   7723  C C   . ALA C 1 99  ? 150.948 163.530 182.141 1.00 32.46  ? 120 ALA C C   1 
ATOM   7724  O O   . ALA C 1 99  ? 150.870 163.077 183.287 1.00 32.46  ? 120 ALA C O   1 
ATOM   7725  C CB  . ALA C 1 99  ? 153.257 163.386 181.183 1.00 32.46  ? 120 ALA C CB  1 
ATOM   7726  N N   . GLN C 1 100 ? 150.264 164.607 181.747 1.00 31.12  ? 121 GLN C N   1 
ATOM   7727  C CA  . GLN C 1 100 ? 149.331 165.269 182.653 1.00 31.12  ? 121 GLN C CA  1 
ATOM   7728  C C   . GLN C 1 100 ? 148.122 164.386 182.947 1.00 31.12  ? 121 GLN C C   1 
ATOM   7729  O O   . GLN C 1 100 ? 147.679 164.298 184.100 1.00 31.12  ? 121 GLN C O   1 
ATOM   7730  C CB  . GLN C 1 100 ? 148.896 166.609 182.060 1.00 31.12  ? 121 GLN C CB  1 
ATOM   7731  C CG  . GLN C 1 100 ? 150.060 167.514 181.683 1.00 31.12  ? 121 GLN C CG  1 
ATOM   7732  C CD  . GLN C 1 100 ? 149.612 168.865 181.168 1.00 31.12  ? 121 GLN C CD  1 
ATOM   7733  O OE1 . GLN C 1 100 ? 148.417 169.142 181.074 1.00 31.12  ? 121 GLN C OE1 1 
ATOM   7734  N NE2 . GLN C 1 100 ? 150.572 169.717 180.830 1.00 31.12  ? 121 GLN C NE2 1 
ATOM   7735  N N   . VAL C 1 101 ? 147.600 163.704 181.923 1.00 27.63  ? 122 VAL C N   1 
ATOM   7736  C CA  . VAL C 1 101 ? 146.494 162.768 182.113 1.00 27.63  ? 122 VAL C CA  1 
ATOM   7737  C C   . VAL C 1 101 ? 146.941 161.576 182.956 1.00 27.63  ? 122 VAL C C   1 
ATOM   7738  O O   . VAL C 1 101 ? 146.197 161.102 183.829 1.00 27.63  ? 122 VAL C O   1 
ATOM   7739  C CB  . VAL C 1 101 ? 145.936 162.340 180.740 1.00 27.63  ? 122 VAL C CB  1 
ATOM   7740  C CG1 . VAL C 1 101 ? 144.857 161.275 180.877 1.00 27.63  ? 122 VAL C CG1 1 
ATOM   7741  C CG2 . VAL C 1 101 ? 145.380 163.547 180.007 1.00 27.63  ? 122 VAL C CG2 1 
ATOM   7742  N N   . THR C 1 102 ? 148.178 161.109 182.744 1.00 26.71  ? 123 THR C N   1 
ATOM   7743  C CA  . THR C 1 102 ? 148.723 160.019 183.553 1.00 26.71  ? 123 THR C CA  1 
ATOM   7744  C C   . THR C 1 102 ? 148.882 160.428 185.017 1.00 26.71  ? 123 THR C C   1 
ATOM   7745  O O   . THR C 1 102 ? 148.603 159.635 185.926 1.00 26.71  ? 123 THR C O   1 
ATOM   7746  C CB  . THR C 1 102 ? 150.063 159.561 182.977 1.00 26.71  ? 123 THR C CB  1 
ATOM   7747  O OG1 . THR C 1 102 ? 149.977 159.509 181.548 1.00 26.71  ? 123 THR C OG1 1 
ATOM   7748  C CG2 . THR C 1 102 ? 150.424 158.181 183.501 1.00 26.71  ? 123 THR C CG2 1 
ATOM   7749  N N   . SER C 1 103 ? 149.290 161.677 185.265 1.00 24.91  ? 124 SER C N   1 
ATOM   7750  C CA  . SER C 1 103 ? 149.392 162.167 186.637 1.00 24.91  ? 124 SER C CA  1 
ATOM   7751  C C   . SER C 1 103 ? 148.019 162.326 187.282 1.00 24.91  ? 124 SER C C   1 
ATOM   7752  O O   . SER C 1 103 ? 147.868 162.077 188.483 1.00 24.91  ? 124 SER C O   1 
ATOM   7753  C CB  . SER C 1 103 ? 150.157 163.489 186.668 1.00 24.91  ? 124 SER C CB  1 
ATOM   7754  O OG  . SER C 1 103 ? 151.500 163.307 186.257 1.00 24.91  ? 124 SER C OG  1 
ATOM   7755  N N   . VAL C 1 104 ? 147.011 162.736 186.504 1.00 21.67  ? 125 VAL C N   1 
ATOM   7756  C CA  . VAL C 1 104 ? 145.642 162.829 187.020 1.00 21.67  ? 125 VAL C CA  1 
ATOM   7757  C C   . VAL C 1 104 ? 145.118 161.448 187.419 1.00 21.67  ? 125 VAL C C   1 
ATOM   7758  O O   . VAL C 1 104 ? 144.495 161.281 188.481 1.00 21.67  ? 125 VAL C O   1 
ATOM   7759  C CB  . VAL C 1 104 ? 144.739 163.526 185.982 1.00 21.67  ? 125 VAL C CB  1 
ATOM   7760  C CG1 . VAL C 1 104 ? 143.275 163.363 186.314 1.00 21.67  ? 125 VAL C CG1 1 
ATOM   7761  C CG2 . VAL C 1 104 ? 145.062 165.006 185.930 1.00 21.67  ? 125 VAL C CG2 1 
ATOM   7762  N N   . VAL C 1 105 ? 145.412 160.431 186.599 1.00 23.79  ? 126 VAL C N   1 
ATOM   7763  C CA  . VAL C 1 105 ? 145.063 159.048 186.934 1.00 23.79  ? 126 VAL C CA  1 
ATOM   7764  C C   . VAL C 1 105 ? 145.814 158.586 188.185 1.00 23.79  ? 126 VAL C C   1 
ATOM   7765  O O   . VAL C 1 105 ? 145.257 157.876 189.035 1.00 23.79  ? 126 VAL C O   1 
ATOM   7766  C CB  . VAL C 1 105 ? 145.323 158.136 185.717 1.00 23.79  ? 126 VAL C CB  1 
ATOM   7767  C CG1 . VAL C 1 105 ? 145.182 156.657 186.059 1.00 23.79  ? 126 VAL C CG1 1 
ATOM   7768  C CG2 . VAL C 1 105 ? 144.359 158.481 184.599 1.00 23.79  ? 126 VAL C CG2 1 
ATOM   7769  N N   . ALA C 1 106 ? 147.069 159.028 188.344 1.00 25.50  ? 127 ALA C N   1 
ATOM   7770  C CA  . ALA C 1 106 ? 147.848 158.687 189.538 1.00 25.50  ? 127 ALA C CA  1 
ATOM   7771  C C   . ALA C 1 106 ? 147.255 159.296 190.809 1.00 25.50  ? 127 ALA C C   1 
ATOM   7772  O O   . ALA C 1 106 ? 147.195 158.628 191.850 1.00 25.50  ? 127 ALA C O   1 
ATOM   7773  C CB  . ALA C 1 106 ? 149.298 159.133 189.362 1.00 25.50  ? 127 ALA C CB  1 
ATOM   7774  N N   . LEU C 1 107 ? 146.816 160.559 190.747 1.00 24.26  ? 128 LEU C N   1 
ATOM   7775  C CA  . LEU C 1 107 ? 146.130 161.168 191.892 1.00 24.26  ? 128 LEU C CA  1 
ATOM   7776  C C   . LEU C 1 107 ? 144.802 160.483 192.203 1.00 24.26  ? 128 LEU C C   1 
ATOM   7777  O O   . LEU C 1 107 ? 144.453 160.312 193.381 1.00 24.26  ? 128 LEU C O   1 
ATOM   7778  C CB  . LEU C 1 107 ? 145.913 162.666 191.674 1.00 24.26  ? 128 LEU C CB  1 
ATOM   7779  C CG  . LEU C 1 107 ? 146.986 163.684 192.083 1.00 24.26  ? 128 LEU C CG  1 
ATOM   7780  C CD1 . LEU C 1 107 ? 148.241 163.693 191.245 1.00 24.26  ? 128 LEU C CD1 1 
ATOM   7781  C CD2 . LEU C 1 107 ? 146.344 165.056 192.058 1.00 24.26  ? 128 LEU C CD2 1 
ATOM   7782  N N   . HIS C 1 108 ? 144.051 160.080 191.172 1.00 27.32  ? 129 HIS C N   1 
ATOM   7783  C CA  . HIS C 1 108 ? 142.804 159.363 191.434 1.00 27.32  ? 129 HIS C CA  1 
ATOM   7784  C C   . HIS C 1 108 ? 143.060 157.978 192.016 1.00 27.32  ? 129 HIS C C   1 
ATOM   7785  O O   . HIS C 1 108 ? 142.229 157.459 192.769 1.00 27.32  ? 129 HIS C O   1 
ATOM   7786  C CB  . HIS C 1 108 ? 141.968 159.244 190.165 1.00 27.32  ? 129 HIS C CB  1 
ATOM   7787  C CG  . HIS C 1 108 ? 140.595 158.697 190.403 1.00 27.32  ? 129 HIS C CG  1 
ATOM   7788  N ND1 . HIS C 1 108 ? 139.577 159.454 190.941 1.00 27.32  ? 129 HIS C ND1 1 
ATOM   7789  C CD2 . HIS C 1 108 ? 140.077 157.464 190.195 1.00 27.32  ? 129 HIS C CD2 1 
ATOM   7790  C CE1 . HIS C 1 108 ? 138.488 158.714 191.045 1.00 27.32  ? 129 HIS C CE1 1 
ATOM   7791  N NE2 . HIS C 1 108 ? 138.765 157.502 190.599 1.00 27.32  ? 129 HIS C NE2 1 
ATOM   7792  N N   . LYS C 1 109 ? 144.200 157.371 191.684 1.00 32.30  ? 130 LYS C N   1 
ATOM   7793  C CA  . LYS C 1 109 ? 144.566 156.100 192.300 1.00 32.30  ? 130 LYS C CA  1 
ATOM   7794  C C   . LYS C 1 109 ? 145.024 156.291 193.743 1.00 32.30  ? 130 LYS C C   1 
ATOM   7795  O O   . LYS C 1 109 ? 144.778 155.431 194.596 1.00 32.30  ? 130 LYS C O   1 
ATOM   7796  C CB  . LYS C 1 109 ? 145.655 155.416 191.474 1.00 32.30  ? 130 LYS C CB  1 
ATOM   7797  C CG  . LYS C 1 109 ? 145.830 153.937 191.770 1.00 32.30  ? 130 LYS C CG  1 
ATOM   7798  C CD  . LYS C 1 109 ? 144.607 153.141 191.342 1.00 32.30  ? 130 LYS C CD  1 
ATOM   7799  C CE  . LYS C 1 109 ? 144.371 153.244 189.842 1.00 32.30  ? 130 LYS C CE  1 
ATOM   7800  N NZ  . LYS C 1 109 ? 145.462 152.600 189.060 1.00 32.30  ? 130 LYS C NZ  1 
ATOM   7801  N N   . SER C 1 110 ? 145.688 157.408 194.036 1.00 23.23  ? 131 SER C N   1 
ATOM   7802  C CA  . SER C 1 110 ? 146.280 157.630 195.351 1.00 23.23  ? 131 SER C CA  1 
ATOM   7803  C C   . SER C 1 110 ? 145.390 158.422 196.304 1.00 23.23  ? 131 SER C C   1 
ATOM   7804  O O   . SER C 1 110 ? 145.847 158.752 197.407 1.00 23.23  ? 131 SER C O   1 
ATOM   7805  C CB  . SER C 1 110 ? 147.623 158.347 195.202 1.00 23.23  ? 131 SER C CB  1 
ATOM   7806  O OG  . SER C 1 110 ? 148.223 158.561 196.466 1.00 23.23  ? 131 SER C OG  1 
ATOM   7807  N N   . ASN C 1 111 ? 144.157 158.751 195.893 1.00 25.06  ? 132 ASN C N   1 
ATOM   7808  C CA  . ASN C 1 111 ? 143.227 159.490 196.753 1.00 25.06  ? 132 ASN C CA  1 
ATOM   7809  C C   . ASN C 1 111 ? 142.910 158.750 198.054 1.00 25.06  ? 132 ASN C C   1 
ATOM   7810  O O   . ASN C 1 111 ? 142.847 159.372 199.123 1.00 25.06  ? 132 ASN C O   1 
ATOM   7811  C CB  . ASN C 1 111 ? 141.933 159.772 195.987 1.00 25.06  ? 132 ASN C CB  1 
ATOM   7812  C CG  . ASN C 1 111 ? 141.215 161.020 196.476 1.00 25.06  ? 132 ASN C CG  1 
ATOM   7813  O OD1 . ASN C 1 111 ? 141.205 161.326 197.668 1.00 25.06  ? 132 ASN C OD1 1 
ATOM   7814  N ND2 . ASN C 1 111 ? 140.598 161.743 195.549 1.00 25.06  ? 132 ASN C ND2 1 
ATOM   7815  N N   . GLN C 1 112 ? 142.703 157.429 197.986 1.00 30.30  ? 133 GLN C N   1 
ATOM   7816  C CA  . GLN C 1 112 ? 142.336 156.664 199.179 1.00 30.30  ? 133 GLN C CA  1 
ATOM   7817  C C   . GLN C 1 112 ? 143.480 156.600 200.188 1.00 30.30  ? 133 GLN C C   1 
ATOM   7818  O O   . GLN C 1 112 ? 143.260 156.762 201.396 1.00 30.30  ? 133 GLN C O   1 
ATOM   7819  C CB  . GLN C 1 112 ? 141.895 155.254 198.789 1.00 30.30  ? 133 GLN C CB  1 
ATOM   7820  C CG  . GLN C 1 112 ? 140.674 155.208 197.887 1.00 30.30  ? 133 GLN C CG  1 
ATOM   7821  C CD  . GLN C 1 112 ? 141.035 155.084 196.420 1.00 30.30  ? 133 GLN C CD  1 
ATOM   7822  O OE1 . GLN C 1 112 ? 142.117 155.493 195.999 1.00 30.30  ? 133 GLN C OE1 1 
ATOM   7823  N NE2 . GLN C 1 112 ? 140.127 154.518 195.634 1.00 30.30  ? 133 GLN C NE2 1 
ATOM   7824  N N   . ASN C 1 113 ? 144.708 156.389 199.711 1.00 29.65  ? 134 ASN C N   1 
ATOM   7825  C CA  . ASN C 1 113 ? 145.854 156.378 200.614 1.00 29.65  ? 134 ASN C CA  1 
ATOM   7826  C C   . ASN C 1 113 ? 146.161 157.771 201.148 1.00 29.65  ? 134 ASN C C   1 
ATOM   7827  O O   . ASN C 1 113 ? 146.615 157.903 202.292 1.00 29.65  ? 134 ASN C O   1 
ATOM   7828  C CB  . ASN C 1 113 ? 147.076 155.791 199.911 1.00 29.65  ? 134 ASN C CB  1 
ATOM   7829  C CG  . ASN C 1 113 ? 148.127 155.308 200.886 1.00 29.65  ? 134 ASN C CG  1 
ATOM   7830  O OD1 . ASN C 1 113 ? 147.807 154.747 201.933 1.00 29.65  ? 134 ASN C OD1 1 
ATOM   7831  N ND2 . ASN C 1 113 ? 149.391 155.518 200.545 1.00 29.65  ? 134 ASN C ND2 1 
ATOM   7832  N N   . ALA C 1 114 ? 145.903 158.816 200.350 1.00 26.98  ? 135 ALA C N   1 
ATOM   7833  C CA  . ALA C 1 114 ? 146.050 160.183 200.841 1.00 26.98  ? 135 ALA C CA  1 
ATOM   7834  C C   . ALA C 1 114 ? 145.051 160.485 201.952 1.00 26.98  ? 135 ALA C C   1 
ATOM   7835  O O   . ALA C 1 114 ? 145.393 161.144 202.938 1.00 26.98  ? 135 ALA C O   1 
ATOM   7836  C CB  . ALA C 1 114 ? 145.888 161.174 199.689 1.00 26.98  ? 135 ALA C CB  1 
ATOM   7837  N N   . ALA C 1 115 ? 143.816 159.989 201.818 1.00 33.81  ? 136 ALA C N   1 
ATOM   7838  C CA  . ALA C 1 115 ? 142.831 160.146 202.887 1.00 33.81  ? 136 ALA C CA  1 
ATOM   7839  C C   . ALA C 1 115 ? 143.207 159.331 204.122 1.00 33.81  ? 136 ALA C C   1 
ATOM   7840  O O   . ALA C 1 115 ? 142.961 159.765 205.257 1.00 33.81  ? 136 ALA C O   1 
ATOM   7841  C CB  . ALA C 1 115 ? 141.444 159.748 202.384 1.00 33.81  ? 136 ALA C CB  1 
ATOM   7842  N N   . LYS C 1 116 ? 143.807 158.152 203.920 1.00 37.44  ? 137 LYS C N   1 
ATOM   7843  C CA  . LYS C 1 116 ? 144.264 157.336 205.045 1.00 37.44  ? 137 LYS C CA  1 
ATOM   7844  C C   . LYS C 1 116 ? 145.388 158.018 205.820 1.00 37.44  ? 137 LYS C C   1 
ATOM   7845  O O   . LYS C 1 116 ? 145.435 157.934 207.053 1.00 37.44  ? 137 LYS C O   1 
ATOM   7846  C CB  . LYS C 1 116 ? 144.718 155.964 204.550 1.00 37.44  ? 137 LYS C CB  1 
ATOM   7847  C CG  . LYS C 1 116 ? 143.581 154.994 204.283 1.00 37.44  ? 137 LYS C CG  1 
ATOM   7848  C CD  . LYS C 1 116 ? 144.085 153.560 204.217 1.00 37.44  ? 137 LYS C CD  1 
ATOM   7849  C CE  . LYS C 1 116 ? 144.679 153.112 205.546 1.00 37.44  ? 137 LYS C CE  1 
ATOM   7850  N NZ  . LYS C 1 116 ? 143.832 153.496 206.710 1.00 37.44  ? 137 LYS C NZ  1 
ATOM   7851  N N   . ILE C 1 117 ? 146.308 158.683 205.117 1.00 34.80  ? 138 ILE C N   1 
ATOM   7852  C CA  . ILE C 1 117 ? 147.337 159.467 205.799 1.00 34.80  ? 138 ILE C CA  1 
ATOM   7853  C C   . ILE C 1 117 ? 146.723 160.701 206.461 1.00 34.80  ? 138 ILE C C   1 
ATOM   7854  O O   . ILE C 1 117 ? 147.087 161.064 207.588 1.00 34.80  ? 138 ILE C O   1 
ATOM   7855  C CB  . ILE C 1 117 ? 148.470 159.833 204.820 1.00 34.80  ? 138 ILE C CB  1 
ATOM   7856  C CG1 . ILE C 1 117 ? 149.121 158.567 204.264 1.00 34.80  ? 138 ILE C CG1 1 
ATOM   7857  C CG2 . ILE C 1 117 ? 149.540 160.663 205.497 1.00 34.80  ? 138 ILE C CG2 1 
ATOM   7858  C CD1 . ILE C 1 117 ? 149.955 158.807 203.026 1.00 34.80  ? 138 ILE C CD1 1 
ATOM   7859  N N   . ASN C 1 118 ? 145.753 161.340 205.794 1.00 31.82  ? 139 ASN C N   1 
ATOM   7860  C CA  . ASN C 1 118 ? 145.094 162.529 206.331 1.00 31.82  ? 139 ASN C CA  1 
ATOM   7861  C C   . ASN C 1 118 ? 144.233 162.237 207.554 1.00 31.82  ? 139 ASN C C   1 
ATOM   7862  O O   . ASN C 1 118 ? 143.900 163.167 208.295 1.00 31.82  ? 139 ASN C O   1 
ATOM   7863  C CB  . ASN C 1 118 ? 144.227 163.178 205.252 1.00 31.82  ? 139 ASN C CB  1 
ATOM   7864  C CG  . ASN C 1 118 ? 145.022 164.067 204.323 1.00 31.82  ? 139 ASN C CG  1 
ATOM   7865  O OD1 . ASN C 1 118 ? 145.804 164.908 204.765 1.00 31.82  ? 139 ASN C OD1 1 
ATOM   7866  N ND2 . ASN C 1 118 ? 144.827 163.882 203.023 1.00 31.82  ? 139 ASN C ND2 1 
ATOM   7867  N N   . SER C 1 119 ? 143.859 160.973 207.774 1.00 36.14  ? 140 SER C N   1 
ATOM   7868  C CA  . SER C 1 119 ? 143.107 160.586 208.965 1.00 36.14  ? 140 SER C CA  1 
ATOM   7869  C C   . SER C 1 119 ? 143.898 160.730 210.265 1.00 36.14  ? 140 SER C C   1 
ATOM   7870  O O   . SER C 1 119 ? 143.292 160.688 211.340 1.00 36.14  ? 140 SER C O   1 
ATOM   7871  C CB  . SER C 1 119 ? 142.621 159.143 208.826 1.00 36.14  ? 140 SER C CB  1 
ATOM   7872  O OG  . SER C 1 119 ? 141.713 159.013 207.747 1.00 36.14  ? 140 SER C OG  1 
ATOM   7873  N N   . LEU C 1 120 ? 145.220 160.896 210.199 1.00 37.76  ? 141 LEU C N   1 
ATOM   7874  C CA  . LEU C 1 120 ? 146.050 161.072 211.386 1.00 37.76  ? 141 LEU C CA  1 
ATOM   7875  C C   . LEU C 1 120 ? 146.676 162.461 211.407 1.00 37.76  ? 141 LEU C C   1 
ATOM   7876  O O   . LEU C 1 120 ? 147.886 162.597 211.623 1.00 37.76  ? 141 LEU C O   1 
ATOM   7877  C CB  . LEU C 1 120 ? 147.139 159.999 211.449 1.00 37.76  ? 141 LEU C CB  1 
ATOM   7878  C CG  . LEU C 1 120 ? 146.662 158.558 211.625 1.00 37.76  ? 141 LEU C CG  1 
ATOM   7879  C CD1 . LEU C 1 120 ? 147.828 157.592 211.496 1.00 37.76  ? 141 LEU C CD1 1 
ATOM   7880  C CD2 . LEU C 1 120 ? 145.969 158.391 212.966 1.00 37.76  ? 141 LEU C CD2 1 
ATOM   7881  N N   . ARG C 1 121 ? 145.858 163.488 211.144 1.00 30.06  ? 142 ARG C N   1 
ATOM   7882  C CA  . ARG C 1 121 ? 146.341 164.867 211.112 1.00 30.06  ? 142 ARG C CA  1 
ATOM   7883  C C   . ARG C 1 121 ? 146.836 165.318 212.483 1.00 30.06  ? 142 ARG C C   1 
ATOM   7884  O O   . ARG C 1 121 ? 147.851 166.020 212.585 1.00 30.06  ? 142 ARG C O   1 
ATOM   7885  C CB  . ARG C 1 121 ? 145.231 165.788 210.592 1.00 30.06  ? 142 ARG C CB  1 
ATOM   7886  C CG  . ARG C 1 121 ? 145.465 167.279 210.798 1.00 30.06  ? 142 ARG C CG  1 
ATOM   7887  C CD  . ARG C 1 121 ? 144.784 168.125 209.733 1.00 30.06  ? 142 ARG C CD  1 
ATOM   7888  N NE  . ARG C 1 121 ? 143.350 167.877 209.643 1.00 30.06  ? 142 ARG C NE  1 
ATOM   7889  C CZ  . ARG C 1 121 ? 142.748 167.336 208.592 1.00 30.06  ? 142 ARG C CZ  1 
ATOM   7890  N NH1 . ARG C 1 121 ? 143.429 166.970 207.519 1.00 30.06  ? 142 ARG C NH1 1 
ATOM   7891  N NH2 . ARG C 1 121 ? 141.431 167.159 208.619 1.00 30.06  ? 142 ARG C NH2 1 
ATOM   7892  N N   . ASP C 1 122 ? 146.154 164.895 213.551 1.00 42.06  ? 143 ASP C N   1 
ATOM   7893  C CA  . ASP C 1 122 ? 146.631 165.191 214.899 1.00 42.06  ? 143 ASP C CA  1 
ATOM   7894  C C   . ASP C 1 122 ? 147.910 164.431 215.230 1.00 42.06  ? 143 ASP C C   1 
ATOM   7895  O O   . ASP C 1 122 ? 148.699 164.886 216.066 1.00 42.06  ? 143 ASP C O   1 
ATOM   7896  C CB  . ASP C 1 122 ? 145.547 164.869 215.925 1.00 42.06  ? 143 ASP C CB  1 
ATOM   7897  C CG  . ASP C 1 122 ? 145.631 165.751 217.155 1.00 42.06  ? 143 ASP C CG  1 
ATOM   7898  O OD1 . ASP C 1 122 ? 145.944 166.951 217.008 1.00 42.06  ? 143 ASP C OD1 1 
ATOM   7899  O OD2 . ASP C 1 122 ? 145.389 165.243 218.270 1.00 42.06  ? 143 ASP C OD2 1 
ATOM   7900  N N   . SER C 1 123 ? 148.133 163.278 214.595 1.00 45.14  ? 144 SER C N   1 
ATOM   7901  C CA  . SER C 1 123 ? 149.387 162.561 214.790 1.00 45.14  ? 144 SER C CA  1 
ATOM   7902  C C   . SER C 1 123 ? 150.531 163.206 214.018 1.00 45.14  ? 144 SER C C   1 
ATOM   7903  O O   . SER C 1 123 ? 151.683 163.157 214.465 1.00 45.14  ? 144 SER C O   1 
ATOM   7904  C CB  . SER C 1 123 ? 149.228 161.098 214.380 1.00 45.14  ? 144 SER C CB  1 
ATOM   7905  O OG  . SER C 1 123 ? 148.324 160.425 215.237 1.00 45.14  ? 144 SER C OG  1 
ATOM   7906  N N   . ILE C 1 124 ? 150.235 163.796 212.858 1.00 38.04  ? 145 ILE C N   1 
ATOM   7907  C CA  . ILE C 1 124 ? 151.268 164.433 212.043 1.00 38.04  ? 145 ILE C CA  1 
ATOM   7908  C C   . ILE C 1 124 ? 151.766 165.715 212.707 1.00 38.04  ? 145 ILE C C   1 
ATOM   7909  O O   . ILE C 1 124 ? 152.972 165.985 212.743 1.00 38.04  ? 145 ILE C O   1 
ATOM   7910  C CB  . ILE C 1 124 ? 150.724 164.679 210.621 1.00 38.04  ? 145 ILE C CB  1 
ATOM   7911  C CG1 . ILE C 1 124 ? 150.617 163.357 209.861 1.00 38.04  ? 145 ILE C CG1 1 
ATOM   7912  C CG2 . ILE C 1 124 ? 151.598 165.646 209.830 1.00 38.04  ? 145 ILE C CG2 1 
ATOM   7913  C CD1 . ILE C 1 124 ? 149.918 163.476 208.527 1.00 38.04  ? 145 ILE C CD1 1 
ATOM   7914  N N   . THR C 1 125 ? 150.858 166.500 213.281 1.00 38.82  ? 146 THR C N   1 
ATOM   7915  C CA  . THR C 1 125 ? 151.217 167.805 213.822 1.00 38.82  ? 146 THR C CA  1 
ATOM   7916  C C   . THR C 1 125 ? 151.814 167.748 215.225 1.00 38.82  ? 146 THR C C   1 
ATOM   7917  O O   . THR C 1 125 ? 152.200 168.797 215.751 1.00 38.82  ? 146 THR C O   1 
ATOM   7918  C CB  . THR C 1 125 ? 149.993 168.724 213.834 1.00 38.82  ? 146 THR C CB  1 
ATOM   7919  O OG1 . THR C 1 125 ? 150.403 170.064 214.132 1.00 38.82  ? 146 THR C OG1 1 
ATOM   7920  C CG2 . THR C 1 125 ? 148.989 168.261 214.878 1.00 38.82  ? 146 THR C CG2 1 
ATOM   7921  N N   . LYS C 1 126 ? 151.903 166.573 215.845 1.00 42.10  ? 147 LYS C N   1 
ATOM   7922  C CA  . LYS C 1 126 ? 152.382 166.469 217.218 1.00 42.10  ? 147 LYS C CA  1 
ATOM   7923  C C   . LYS C 1 126 ? 153.844 166.051 217.328 1.00 42.10  ? 147 LYS C C   1 
ATOM   7924  O O   . LYS C 1 126 ? 154.342 165.891 218.448 1.00 42.10  ? 147 LYS C O   1 
ATOM   7925  C CB  . LYS C 1 126 ? 151.501 165.496 218.014 1.00 42.10  ? 147 LYS C CB  1 
ATOM   7926  C CG  . LYS C 1 126 ? 151.758 164.019 217.748 1.00 42.10  ? 147 LYS C CG  1 
ATOM   7927  C CD  . LYS C 1 126 ? 150.606 163.166 218.254 1.00 42.10  ? 147 LYS C CD  1 
ATOM   7928  C CE  . LYS C 1 126 ? 151.006 161.703 218.358 1.00 42.10  ? 147 LYS C CE  1 
ATOM   7929  N NZ  . LYS C 1 126 ? 151.550 161.175 217.078 1.00 42.10  ? 147 LYS C NZ  1 
ATOM   7930  N N   . THR C 1 127 ? 154.545 165.888 216.207 1.00 46.39  ? 148 THR C N   1 
ATOM   7931  C CA  . THR C 1 127 ? 155.937 165.454 216.239 1.00 46.39  ? 148 THR C CA  1 
ATOM   7932  C C   . THR C 1 127 ? 156.851 166.550 216.776 1.00 46.39  ? 148 THR C C   1 
ATOM   7933  O O   . THR C 1 127 ? 156.602 167.745 216.600 1.00 46.39  ? 148 THR C O   1 
ATOM   7934  C CB  . THR C 1 127 ? 156.404 165.041 214.845 1.00 46.39  ? 148 THR C CB  1 
ATOM   7935  O OG1 . THR C 1 127 ? 156.672 166.210 214.061 1.00 46.39  ? 148 THR C OG1 1 
ATOM   7936  C CG2 . THR C 1 127 ? 155.351 164.194 214.162 1.00 46.39  ? 148 THR C CG2 1 
ATOM   7937  N N   . ASN C 1 128 ? 157.929 166.124 217.442 1.00 43.10  ? 149 ASN C N   1 
ATOM   7938  C CA  . ASN C 1 128 ? 158.884 167.063 218.014 1.00 43.10  ? 149 ASN C CA  1 
ATOM   7939  C C   . ASN C 1 128 ? 160.332 166.657 217.762 1.00 43.10  ? 149 ASN C C   1 
ATOM   7940  O O   . ASN C 1 128 ? 161.238 167.281 218.328 1.00 43.10  ? 149 ASN C O   1 
ATOM   7941  C CB  . ASN C 1 128 ? 158.651 167.218 219.521 1.00 43.10  ? 149 ASN C CB  1 
ATOM   7942  C CG  . ASN C 1 128 ? 158.591 165.887 220.238 1.00 43.10  ? 149 ASN C CG  1 
ATOM   7943  O OD1 . ASN C 1 128 ? 157.634 165.128 220.084 1.00 43.10  ? 149 ASN C OD1 1 
ATOM   7944  N ND2 . ASN C 1 128 ? 159.617 165.593 221.028 1.00 43.10  ? 149 ASN C ND2 1 
ATOM   7945  N N   . GLN C 1 129 ? 160.581 165.644 216.941 1.00 42.87  ? 150 GLN C N   1 
ATOM   7946  C CA  . GLN C 1 129 ? 161.929 165.232 216.582 1.00 42.87  ? 150 GLN C CA  1 
ATOM   7947  C C   . GLN C 1 129 ? 162.167 165.494 215.101 1.00 42.87  ? 150 GLN C C   1 
ATOM   7948  O O   . GLN C 1 129 ? 161.270 165.919 214.369 1.00 42.87  ? 150 GLN C O   1 
ATOM   7949  C CB  . GLN C 1 129 ? 162.168 163.752 216.904 1.00 42.87  ? 150 GLN C CB  1 
ATOM   7950  C CG  . GLN C 1 129 ? 162.315 163.452 218.383 1.00 42.87  ? 150 GLN C CG  1 
ATOM   7951  C CD  . GLN C 1 129 ? 162.634 161.996 218.647 1.00 42.87  ? 150 GLN C CD  1 
ATOM   7952  O OE1 . GLN C 1 129 ? 162.679 161.182 217.725 1.00 42.87  ? 150 GLN C OE1 1 
ATOM   7953  N NE2 . GLN C 1 129 ? 162.862 161.660 219.911 1.00 42.87  ? 150 GLN C NE2 1 
ATOM   7954  N N   . ALA C 1 130 ? 163.410 165.256 214.676 1.00 28.78  ? 151 ALA C N   1 
ATOM   7955  C CA  . ALA C 1 130 ? 163.800 165.435 213.283 1.00 28.78  ? 151 ALA C CA  1 
ATOM   7956  C C   . ALA C 1 130 ? 163.080 164.455 212.368 1.00 28.78  ? 151 ALA C C   1 
ATOM   7957  O O   . ALA C 1 130 ? 162.267 164.866 211.538 1.00 28.78  ? 151 ALA C O   1 
ATOM   7958  C CB  . ALA C 1 130 ? 165.314 165.282 213.130 1.00 28.78  ? 151 ALA C CB  1 
ATOM   7959  N N   . VAL C 1 131 ? 163.366 163.161 212.514 1.00 25.92  ? 152 VAL C N   1 
ATOM   7960  C CA  . VAL C 1 131 ? 162.733 162.101 211.733 1.00 25.92  ? 152 VAL C CA  1 
ATOM   7961  C C   . VAL C 1 131 ? 162.227 161.040 212.700 1.00 25.92  ? 152 VAL C C   1 
ATOM   7962  O O   . VAL C 1 131 ? 162.994 160.542 213.531 1.00 25.92  ? 152 VAL C O   1 
ATOM   7963  C CB  . VAL C 1 131 ? 163.702 161.465 210.712 1.00 25.92  ? 152 VAL C CB  1 
ATOM   7964  C CG1 . VAL C 1 131 ? 163.003 160.371 209.921 1.00 25.92  ? 152 VAL C CG1 1 
ATOM   7965  C CG2 . VAL C 1 131 ? 164.281 162.503 209.757 1.00 25.92  ? 152 VAL C CG2 1 
ATOM   7966  N N   . GLU C 1 132 ? 160.946 160.690 212.595 1.00 35.45  ? 153 GLU C N   1 
ATOM   7967  C CA  . GLU C 1 132 ? 160.404 159.584 213.372 1.00 35.45  ? 153 GLU C CA  1 
ATOM   7968  C C   . GLU C 1 132 ? 159.343 158.870 212.544 1.00 35.45  ? 153 GLU C C   1 
ATOM   7969  O O   . GLU C 1 132 ? 159.076 159.228 211.393 1.00 35.45  ? 153 GLU C O   1 
ATOM   7970  C CB  . GLU C 1 132 ? 159.837 160.058 214.713 1.00 35.45  ? 153 GLU C CB  1 
ATOM   7971  C CG  . GLU C 1 132 ? 158.593 160.915 214.617 1.00 35.45  ? 153 GLU C CG  1 
ATOM   7972  C CD  . GLU C 1 132 ? 158.101 161.352 215.981 1.00 35.45  ? 153 GLU C CD  1 
ATOM   7973  O OE1 . GLU C 1 132 ? 158.759 161.013 216.986 1.00 35.45  ? 153 GLU C OE1 1 
ATOM   7974  O OE2 . GLU C 1 132 ? 157.047 162.013 216.054 1.00 35.45  ? 153 GLU C OE2 1 
ATOM   7975  N N   . GLN C 1 133 ? 158.738 157.847 213.143 1.00 41.91  ? 154 GLN C N   1 
ATOM   7976  C CA  . GLN C 1 133 ? 157.758 157.002 212.481 1.00 41.91  ? 154 GLN C CA  1 
ATOM   7977  C C   . GLN C 1 133 ? 156.424 157.070 213.213 1.00 41.91  ? 154 GLN C C   1 
ATOM   7978  O O   . GLN C 1 133 ? 156.372 157.298 214.425 1.00 41.91  ? 154 GLN C O   1 
ATOM   7979  C CB  . GLN C 1 133 ? 158.233 155.544 212.424 1.00 41.91  ? 154 GLN C CB  1 
ATOM   7980  C CG  . GLN C 1 133 ? 159.608 155.353 211.805 1.00 41.91  ? 154 GLN C CG  1 
ATOM   7981  C CD  . GLN C 1 133 ? 159.610 155.559 210.305 1.00 41.91  ? 154 GLN C CD  1 
ATOM   7982  O OE1 . GLN C 1 133 ? 158.821 154.950 209.584 1.00 41.91  ? 154 GLN C OE1 1 
ATOM   7983  N NE2 . GLN C 1 133 ? 160.501 156.418 209.826 1.00 41.91  ? 154 GLN C NE2 1 
ATOM   7984  N N   . LEU C 1 134 ? 155.342 156.873 212.461 1.00 50.77  ? 155 LEU C N   1 
ATOM   7985  C CA  . LEU C 1 134 ? 154.001 156.766 213.017 1.00 50.77  ? 155 LEU C CA  1 
ATOM   7986  C C   . LEU C 1 134 ? 153.327 155.523 212.453 1.00 50.77  ? 155 LEU C C   1 
ATOM   7987  O O   . LEU C 1 134 ? 153.554 155.146 211.301 1.00 50.77  ? 155 LEU C O   1 
ATOM   7988  C CB  . LEU C 1 134 ? 153.143 158.000 212.705 1.00 50.77  ? 155 LEU C CB  1 
ATOM   7989  C CG  . LEU C 1 134 ? 153.693 159.377 213.074 1.00 50.77  ? 155 LEU C CG  1 
ATOM   7990  C CD1 . LEU C 1 134 ? 152.856 160.467 212.427 1.00 50.77  ? 155 LEU C CD1 1 
ATOM   7991  C CD2 . LEU C 1 134 ? 153.735 159.552 214.582 1.00 50.77  ? 155 LEU C CD2 1 
ATOM   7992  N N   . SER C 1 135 ? 152.487 154.897 213.272 1.00 66.93  ? 156 SER C N   1 
ATOM   7993  C CA  . SER C 1 135 ? 151.835 153.643 212.897 1.00 66.93  ? 156 SER C CA  1 
ATOM   7994  C C   . SER C 1 135 ? 150.656 153.950 211.983 1.00 66.93  ? 156 SER C C   1 
ATOM   7995  O O   . SER C 1 135 ? 149.585 154.353 212.442 1.00 66.93  ? 156 SER C O   1 
ATOM   7996  C CB  . SER C 1 135 ? 151.390 152.880 214.139 1.00 66.93  ? 156 SER C CB  1 
ATOM   7997  O OG  . SER C 1 135 ? 152.504 152.505 214.930 1.00 66.93  ? 156 SER C OG  1 
ATOM   7998  N N   . LEU C 1 136 ? 150.855 153.760 210.677 1.00 62.37  ? 157 LEU C N   1 
ATOM   7999  C CA  . LEU C 1 136 ? 149.779 153.997 209.720 1.00 62.37  ? 157 LEU C CA  1 
ATOM   8000  C C   . LEU C 1 136 ? 148.739 152.885 209.767 1.00 62.37  ? 157 LEU C C   1 
ATOM   8001  O O   . LEU C 1 136 ? 147.533 153.151 209.707 1.00 62.37  ? 157 LEU C O   1 
ATOM   8002  C CB  . LEU C 1 136 ? 150.352 154.135 208.310 1.00 62.37  ? 157 LEU C CB  1 
ATOM   8003  C CG  . LEU C 1 136 ? 149.371 154.518 207.201 1.00 62.37  ? 157 LEU C CG  1 
ATOM   8004  C CD1 . LEU C 1 136 ? 148.592 155.770 207.576 1.00 62.37  ? 157 LEU C CD1 1 
ATOM   8005  C CD2 . LEU C 1 136 ? 150.099 154.708 205.880 1.00 62.37  ? 157 LEU C CD2 1 
ATOM   8006  N N   . GLY C 1 137 ? 149.181 151.643 209.873 1.00 80.70  ? 158 GLY C N   1 
ATOM   8007  C CA  . GLY C 1 137 ? 148.288 150.498 209.911 1.00 80.70  ? 158 GLY C CA  1 
ATOM   8008  C C   . GLY C 1 137 ? 148.884 149.392 210.749 1.00 80.70  ? 158 GLY C C   1 
ATOM   8009  O O   . GLY C 1 137 ? 149.647 149.647 211.686 1.00 80.70  ? 158 GLY C O   1 
ATOM   8010  N N   . VAL C 1 138 ? 148.532 148.150 210.413 1.00 88.80  ? 159 VAL C N   1 
ATOM   8011  C CA  . VAL C 1 138 ? 149.055 147.017 211.168 1.00 88.80  ? 159 VAL C CA  1 
ATOM   8012  C C   . VAL C 1 138 ? 150.473 146.661 210.727 1.00 88.80  ? 159 VAL C C   1 
ATOM   8013  O O   . VAL C 1 138 ? 151.246 146.101 211.513 1.00 88.80  ? 159 VAL C O   1 
ATOM   8014  C CB  . VAL C 1 138 ? 148.100 145.814 211.063 1.00 88.80  ? 159 VAL C CB  1 
ATOM   8015  C CG1 . VAL C 1 138 ? 146.768 146.146 211.714 1.00 88.80  ? 159 VAL C CG1 1 
ATOM   8016  C CG2 . VAL C 1 138 ? 147.881 145.410 209.610 1.00 88.80  ? 159 VAL C CG2 1 
ATOM   8017  N N   . GLN C 1 139 ? 150.844 146.971 209.480 1.00 91.96  ? 160 GLN C N   1 
ATOM   8018  C CA  . GLN C 1 139 ? 152.192 146.703 208.997 1.00 91.96  ? 160 GLN C CA  1 
ATOM   8019  C C   . GLN C 1 139 ? 152.788 147.845 208.187 1.00 91.96  ? 160 GLN C C   1 
ATOM   8020  O O   . GLN C 1 139 ? 153.950 147.744 207.782 1.00 91.96  ? 160 GLN C O   1 
ATOM   8021  C CB  . GLN C 1 139 ? 152.218 145.420 208.148 1.00 91.96  ? 160 GLN C CB  1 
ATOM   8022  C CG  . GLN C 1 139 ? 152.169 144.129 208.950 1.00 91.96  ? 160 GLN C CG  1 
ATOM   8023  C CD  . GLN C 1 139 ? 153.391 143.943 209.828 1.00 91.96  ? 160 GLN C CD  1 
ATOM   8024  O OE1 . GLN C 1 139 ? 153.299 143.975 211.055 1.00 91.96  ? 160 GLN C OE1 1 
ATOM   8025  N NE2 . GLN C 1 139 ? 154.545 143.747 209.201 1.00 91.96  ? 160 GLN C NE2 1 
ATOM   8026  N N   . GLU C 1 140 ? 152.044 148.918 207.937 1.00 79.65  ? 161 GLU C N   1 
ATOM   8027  C CA  . GLU C 1 140 ? 152.535 150.059 207.181 1.00 79.65  ? 161 GLU C CA  1 
ATOM   8028  C C   . GLU C 1 140 ? 152.781 151.236 208.114 1.00 79.65  ? 161 GLU C C   1 
ATOM   8029  O O   . GLU C 1 140 ? 152.125 151.379 209.150 1.00 79.65  ? 161 GLU C O   1 
ATOM   8030  C CB  . GLU C 1 140 ? 151.546 150.461 206.082 1.00 79.65  ? 161 GLU C CB  1 
ATOM   8031  C CG  . GLU C 1 140 ? 151.138 149.319 205.166 1.00 79.65  ? 161 GLU C CG  1 
ATOM   8032  C CD  . GLU C 1 140 ? 149.795 148.725 205.538 1.00 79.65  ? 161 GLU C CD  1 
ATOM   8033  O OE1 . GLU C 1 140 ? 149.637 148.286 206.696 1.00 79.65  ? 161 GLU C OE1 1 
ATOM   8034  O OE2 . GLU C 1 140 ? 148.895 148.699 204.672 1.00 79.65  ? 161 GLU C OE2 1 
ATOM   8035  N N   . THR C 1 141 ? 153.737 152.082 207.736 1.00 57.41  ? 162 THR C N   1 
ATOM   8036  C CA  . THR C 1 141 ? 154.108 153.220 208.561 1.00 57.41  ? 162 THR C CA  1 
ATOM   8037  C C   . THR C 1 141 ? 154.491 154.391 207.668 1.00 57.41  ? 162 THR C C   1 
ATOM   8038  O O   . THR C 1 141 ? 154.815 154.223 206.489 1.00 57.41  ? 162 THR C O   1 
ATOM   8039  C CB  . THR C 1 141 ? 155.255 152.870 209.520 1.00 57.41  ? 162 THR C CB  1 
ATOM   8040  O OG1 . THR C 1 141 ? 155.492 153.969 210.408 1.00 57.41  ? 162 THR C OG1 1 
ATOM   8041  C CG2 . THR C 1 141 ? 156.531 152.546 208.754 1.00 57.41  ? 162 THR C CG2 1 
ATOM   8042  N N   . VAL C 1 142 ? 154.422 155.588 208.241 1.00 42.91  ? 163 VAL C N   1 
ATOM   8043  C CA  . VAL C 1 142 ? 154.872 156.797 207.573 1.00 42.91  ? 163 VAL C CA  1 
ATOM   8044  C C   . VAL C 1 142 ? 156.175 157.255 208.221 1.00 42.91  ? 163 VAL C C   1 
ATOM   8045  O O   . VAL C 1 142 ? 156.567 156.786 209.288 1.00 42.91  ? 163 VAL C O   1 
ATOM   8046  C CB  . VAL C 1 142 ? 153.810 157.912 207.601 1.00 42.91  ? 163 VAL C CB  1 
ATOM   8047  C CG1 . VAL C 1 142 ? 152.532 157.441 206.929 1.00 42.91  ? 163 VAL C CG1 1 
ATOM   8048  C CG2 . VAL C 1 142 ? 153.542 158.352 209.024 1.00 42.91  ? 163 VAL C CG2 1 
ATOM   8049  N N   . SER C 1 143 ? 156.842 158.198 207.560 1.00 28.43  ? 164 SER C N   1 
ATOM   8050  C CA  . SER C 1 143 ? 158.204 158.604 207.896 1.00 28.43  ? 164 SER C CA  1 
ATOM   8051  C C   . SER C 1 143 ? 158.275 160.129 207.982 1.00 28.43  ? 164 SER C C   1 
ATOM   8052  O O   . SER C 1 143 ? 159.029 160.767 207.248 1.00 28.43  ? 164 SER C O   1 
ATOM   8053  C CB  . SER C 1 143 ? 159.205 158.051 206.887 1.00 28.43  ? 164 SER C CB  1 
ATOM   8054  O OG  . SER C 1 143 ? 158.914 158.513 205.583 1.00 28.43  ? 164 SER C OG  1 
ATOM   8055  N N   . VAL C 1 144 ? 157.401 160.700 208.826 1.00 20.93  ? 165 VAL C N   1 
ATOM   8056  C CA  . VAL C 1 144 ? 157.287 162.149 209.008 1.00 20.93  ? 165 VAL C CA  1 
ATOM   8057  C C   . VAL C 1 144 ? 158.626 162.758 209.418 1.00 20.93  ? 165 VAL C C   1 
ATOM   8058  O O   . VAL C 1 144 ? 159.389 162.175 210.200 1.00 20.93  ? 165 VAL C O   1 
ATOM   8059  C CB  . VAL C 1 144 ? 156.157 162.455 210.012 1.00 20.93  ? 165 VAL C CB  1 
ATOM   8060  C CG1 . VAL C 1 144 ? 156.431 161.876 211.401 1.00 20.93  ? 165 VAL C CG1 1 
ATOM   8061  C CG2 . VAL C 1 144 ? 155.871 163.953 210.094 1.00 20.93  ? 165 VAL C CG2 1 
ATOM   8062  N N   . LEU C 1 145 ? 158.958 163.899 208.813 1.00 16.64  ? 166 LEU C N   1 
ATOM   8063  C CA  . LEU C 1 145 ? 160.285 164.477 208.949 1.00 16.64  ? 166 LEU C CA  1 
ATOM   8064  C C   . LEU C 1 145 ? 160.238 165.993 208.809 1.00 16.64  ? 166 LEU C C   1 
ATOM   8065  O O   . LEU C 1 145 ? 159.536 166.527 207.947 1.00 16.64  ? 166 LEU C O   1 
ATOM   8066  C CB  . LEU C 1 145 ? 161.250 163.827 207.934 1.00 16.64  ? 166 LEU C CB  1 
ATOM   8067  C CG  . LEU C 1 145 ? 161.035 163.835 206.413 1.00 16.64  ? 166 LEU C CG  1 
ATOM   8068  C CD1 . LEU C 1 145 ? 161.576 165.075 205.724 1.00 16.64  ? 166 LEU C CD1 1 
ATOM   8069  C CD2 . LEU C 1 145 ? 161.633 162.577 205.789 1.00 16.64  ? 166 LEU C CD2 1 
ATOM   8070  N N   . MET C 1 146 ? 160.991 166.675 209.673 1.00 31.15  ? 167 MET C N   1 
ATOM   8071  C CA  . MET C 1 146 ? 161.123 168.126 209.680 1.00 31.15  ? 167 MET C CA  1 
ATOM   8072  C C   . MET C 1 146 ? 162.594 168.515 209.676 1.00 31.15  ? 167 MET C C   1 
ATOM   8073  O O   . MET C 1 146 ? 163.390 167.969 210.445 1.00 31.15  ? 167 MET C O   1 
ATOM   8074  C CB  . MET C 1 146 ? 160.428 168.744 210.900 1.00 31.15  ? 167 MET C CB  1 
ATOM   8075  C CG  . MET C 1 146 ? 160.444 170.264 210.925 1.00 31.15  ? 167 MET C CG  1 
ATOM   8076  S SD  . MET C 1 146 ? 159.517 171.056 209.608 1.00 31.15  ? 167 MET C SD  1 
ATOM   8077  C CE  . MET C 1 146 ? 160.348 172.638 209.534 1.00 31.15  ? 167 MET C CE  1 
ATOM   8078  N N   . GLY C 1 147 ? 162.949 169.461 208.810 1.00 30.35  ? 168 GLY C N   1 
ATOM   8079  C CA  . GLY C 1 147 ? 164.322 169.916 208.708 1.00 30.35  ? 168 GLY C CA  1 
ATOM   8080  C C   . GLY C 1 147 ? 164.837 170.727 209.880 1.00 30.35  ? 168 GLY C C   1 
ATOM   8081  O O   . GLY C 1 147 ? 165.965 170.516 210.336 1.00 30.35  ? 168 GLY C O   1 
ATOM   8082  N N   . LEU C 1 148 ? 164.029 171.661 210.374 1.00 35.22  ? 169 LEU C N   1 
ATOM   8083  C CA  . LEU C 1 148 ? 164.462 172.577 211.421 1.00 35.22  ? 169 LEU C CA  1 
ATOM   8084  C C   . LEU C 1 148 ? 164.166 172.079 212.825 1.00 35.22  ? 169 LEU C C   1 
ATOM   8085  O O   . LEU C 1 148 ? 164.557 172.746 213.785 1.00 35.22  ? 169 LEU C O   1 
ATOM   8086  C CB  . LEU C 1 148 ? 163.815 173.955 211.240 1.00 35.22  ? 169 LEU C CB  1 
ATOM   8087  C CG  . LEU C 1 148 ? 164.511 174.989 210.354 1.00 35.22  ? 169 LEU C CG  1 
ATOM   8088  C CD1 . LEU C 1 148 ? 164.408 174.642 208.885 1.00 35.22  ? 169 LEU C CD1 1 
ATOM   8089  C CD2 . LEU C 1 148 ? 163.931 176.367 210.623 1.00 35.22  ? 169 LEU C CD2 1 
ATOM   8090  N N   . GLN C 1 149 ? 163.512 170.924 212.972 1.00 43.21  ? 170 GLN C N   1 
ATOM   8091  C CA  . GLN C 1 149 ? 163.118 170.450 214.295 1.00 43.21  ? 170 GLN C CA  1 
ATOM   8092  C C   . GLN C 1 149 ? 164.312 170.043 215.151 1.00 43.21  ? 170 GLN C C   1 
ATOM   8093  O O   . GLN C 1 149 ? 164.191 170.004 216.379 1.00 43.21  ? 170 GLN C O   1 
ATOM   8094  C CB  . GLN C 1 149 ? 162.141 169.281 214.164 1.00 43.21  ? 170 GLN C CB  1 
ATOM   8095  C CG  . GLN C 1 149 ? 161.183 169.128 215.337 1.00 43.21  ? 170 GLN C CG  1 
ATOM   8096  C CD  . GLN C 1 149 ? 160.700 170.457 215.883 1.00 43.21  ? 170 GLN C CD  1 
ATOM   8097  O OE1 . GLN C 1 149 ? 159.976 171.193 215.211 1.00 43.21  ? 170 GLN C OE1 1 
ATOM   8098  N NE2 . GLN C 1 149 ? 161.100 170.773 217.108 1.00 43.21  ? 170 GLN C NE2 1 
ATOM   8099  N N   . ASP C 1 150 ? 165.461 169.754 214.539 1.00 47.54  ? 171 ASP C N   1 
ATOM   8100  C CA  . ASP C 1 150 ? 166.669 169.539 215.324 1.00 47.54  ? 171 ASP C CA  1 
ATOM   8101  C C   . ASP C 1 150 ? 167.233 170.856 215.849 1.00 47.54  ? 171 ASP C C   1 
ATOM   8102  O O   . ASP C 1 150 ? 167.666 170.932 217.004 1.00 47.54  ? 171 ASP C O   1 
ATOM   8103  C CB  . ASP C 1 150 ? 167.715 168.804 214.489 1.00 47.54  ? 171 ASP C CB  1 
ATOM   8104  C CG  . ASP C 1 150 ? 168.928 168.403 215.299 1.00 47.54  ? 171 ASP C CG  1 
ATOM   8105  O OD1 . ASP C 1 150 ? 168.818 167.451 216.100 1.00 47.54  ? 171 ASP C OD1 1 
ATOM   8106  O OD2 . ASP C 1 150 ? 169.991 169.038 215.138 1.00 47.54  ? 171 ASP C OD2 1 
ATOM   8107  N N   . GLN C 1 151 ? 167.217 171.909 215.025 1.00 52.06  ? 172 GLN C N   1 
ATOM   8108  C CA  . GLN C 1 151 ? 167.894 173.156 215.370 1.00 52.06  ? 172 GLN C CA  1 
ATOM   8109  C C   . GLN C 1 151 ? 167.161 173.975 216.425 1.00 52.06  ? 172 GLN C C   1 
ATOM   8110  O O   . GLN C 1 151 ? 167.772 174.862 217.030 1.00 52.06  ? 172 GLN C O   1 
ATOM   8111  C CB  . GLN C 1 151 ? 168.104 174.011 214.120 1.00 52.06  ? 172 GLN C CB  1 
ATOM   8112  C CG  . GLN C 1 151 ? 169.126 173.445 213.150 1.00 52.06  ? 172 GLN C CG  1 
ATOM   8113  C CD  . GLN C 1 151 ? 169.407 174.379 211.991 1.00 52.06  ? 172 GLN C CD  1 
ATOM   8114  O OE1 . GLN C 1 151 ? 168.803 175.444 211.877 1.00 52.06  ? 172 GLN C OE1 1 
ATOM   8115  N NE2 . GLN C 1 151 ? 170.330 173.983 211.122 1.00 52.06  ? 172 GLN C NE2 1 
ATOM   8116  N N   . ILE C 1 152 ? 165.880 173.706 216.664 1.00 45.97  ? 173 ILE C N   1 
ATOM   8117  C CA  . ILE C 1 152 ? 165.169 174.333 217.773 1.00 45.97  ? 173 ILE C CA  1 
ATOM   8118  C C   . ILE C 1 152 ? 164.840 173.189 218.733 1.00 45.97  ? 173 ILE C C   1 
ATOM   8119  O O   . ILE C 1 152 ? 163.752 173.110 219.314 1.00 45.97  ? 173 ILE C O   1 
ATOM   8120  C CB  . ILE C 1 152 ? 163.940 175.150 217.309 1.00 45.97  ? 173 ILE C CB  1 
ATOM   8121  C CG1 . ILE C 1 152 ? 164.321 176.120 216.192 1.00 45.97  ? 173 ILE C CG1 1 
ATOM   8122  C CG2 . ILE C 1 152 ? 163.471 176.128 218.377 1.00 45.97  ? 173 ILE C CG2 1 
ATOM   8123  C CD1 . ILE C 1 152 ? 163.847 175.740 214.823 1.00 45.97  ? 173 ILE C CD1 1 
ATOM   8124  N N   . ASN C 1 153 ? 165.766 172.234 218.827 1.00 51.19  ? 174 ASN C N   1 
ATOM   8125  C CA  . ASN C 1 153 ? 165.801 171.305 219.948 1.00 51.19  ? 174 ASN C CA  1 
ATOM   8126  C C   . ASN C 1 153 ? 167.204 171.054 220.480 1.00 51.19  ? 174 ASN C C   1 
ATOM   8127  O O   . ASN C 1 153 ? 167.345 170.306 221.453 1.00 51.19  ? 174 ASN C O   1 
ATOM   8128  C CB  . ASN C 1 153 ? 165.151 169.962 219.577 1.00 51.19  ? 174 ASN C CB  1 
ATOM   8129  C CG  . ASN C 1 153 ? 163.660 169.945 219.847 1.00 51.19  ? 174 ASN C CG  1 
ATOM   8130  O OD1 . ASN C 1 153 ? 162.849 169.782 218.936 1.00 51.19  ? 174 ASN C OD1 1 
ATOM   8131  N ND2 . ASN C 1 153 ? 163.290 170.112 221.111 1.00 51.19  ? 174 ASN C ND2 1 
ATOM   8132  N N   . THR C 1 154 ? 168.243 171.644 219.884 1.00 51.75  ? 175 THR C N   1 
ATOM   8133  C CA  . THR C 1 154 ? 169.599 171.504 220.396 1.00 51.75  ? 175 THR C CA  1 
ATOM   8134  C C   . THR C 1 154 ? 170.399 172.799 220.402 1.00 51.75  ? 175 THR C C   1 
ATOM   8135  O O   . THR C 1 154 ? 171.484 172.821 220.994 1.00 51.75  ? 175 THR C O   1 
ATOM   8136  C CB  . THR C 1 154 ? 170.380 170.449 219.594 1.00 51.75  ? 175 THR C CB  1 
ATOM   8137  O OG1 . THR C 1 154 ? 171.587 170.121 220.289 1.00 51.75  ? 175 THR C OG1 1 
ATOM   8138  C CG2 . THR C 1 154 ? 170.741 170.970 218.213 1.00 51.75  ? 175 THR C CG2 1 
ATOM   8139  N N   . ASN C 1 155 ? 169.915 173.867 219.772 1.00 57.10  ? 176 ASN C N   1 
ATOM   8140  C CA  . ASN C 1 155 ? 170.653 175.121 219.691 1.00 57.10  ? 176 ASN C CA  1 
ATOM   8141  C C   . ASN C 1 155 ? 169.909 176.285 220.325 1.00 57.10  ? 176 ASN C C   1 
ATOM   8142  O O   . ASN C 1 155 ? 170.496 177.032 221.116 1.00 57.10  ? 176 ASN C O   1 
ATOM   8143  C CB  . ASN C 1 155 ? 170.975 175.444 218.223 1.00 57.10  ? 176 ASN C CB  1 
ATOM   8144  C CG  . ASN C 1 155 ? 171.441 176.872 218.030 1.00 57.10  ? 176 ASN C CG  1 
ATOM   8145  O OD1 . ASN C 1 155 ? 172.483 177.273 218.549 1.00 57.10  ? 176 ASN C OD1 1 
ATOM   8146  N ND2 . ASN C 1 155 ? 170.671 177.650 217.279 1.00 57.10  ? 176 ASN C ND2 1 
ATOM   8147  N N   . LEU C 1 156 ? 168.630 176.463 220.000 1.00 48.86  ? 177 LEU C N   1 
ATOM   8148  C CA  . LEU C 1 156 ? 167.860 177.586 220.518 1.00 48.86  ? 177 LEU C CA  1 
ATOM   8149  C C   . LEU C 1 156 ? 167.220 177.289 221.867 1.00 48.86  ? 177 LEU C C   1 
ATOM   8150  O O   . LEU C 1 156 ? 167.005 178.214 222.658 1.00 48.86  ? 177 LEU C O   1 
ATOM   8151  C CB  . LEU C 1 156 ? 166.783 177.987 219.507 1.00 48.86  ? 177 LEU C CB  1 
ATOM   8152  C CG  . LEU C 1 156 ? 166.370 179.458 219.495 1.00 48.86  ? 177 LEU C CG  1 
ATOM   8153  C CD1 . LEU C 1 156 ? 167.524 180.321 219.023 1.00 48.86  ? 177 LEU C CD1 1 
ATOM   8154  C CD2 . LEU C 1 156 ? 165.164 179.655 218.599 1.00 48.86  ? 177 LEU C CD2 1 
ATOM   8155  N N   . VAL C 1 157 ? 166.899 176.026 222.135 1.00 55.69  ? 178 VAL C N   1 
ATOM   8156  C CA  . VAL C 1 157 ? 166.338 175.581 223.414 1.00 55.69  ? 178 VAL C CA  1 
ATOM   8157  C C   . VAL C 1 157 ? 167.272 175.795 224.614 1.00 55.69  ? 178 VAL C C   1 
ATOM   8158  O O   . VAL C 1 157 ? 166.783 176.327 225.623 1.00 55.69  ? 178 VAL C O   1 
ATOM   8159  C CB  . VAL C 1 157 ? 165.858 174.117 223.304 1.00 55.69  ? 178 VAL C CB  1 
ATOM   8160  C CG1 . VAL C 1 157 ? 165.433 173.551 224.655 1.00 55.69  ? 178 VAL C CG1 1 
ATOM   8161  C CG2 . VAL C 1 157 ? 164.704 174.031 222.336 1.00 55.69  ? 178 VAL C CG2 1 
ATOM   8162  N N   . PRO C 1 158 ? 168.581 175.441 224.605 1.00 52.67  ? 179 PRO C N   1 
ATOM   8163  C CA  . PRO C 1 158 ? 169.386 175.671 225.826 1.00 52.67  ? 179 PRO C CA  1 
ATOM   8164  C C   . PRO C 1 158 ? 169.633 177.136 226.178 1.00 52.67  ? 179 PRO C C   1 
ATOM   8165  O O   . PRO C 1 158 ? 169.987 177.416 227.329 1.00 52.67  ? 179 PRO C O   1 
ATOM   8166  C CB  . PRO C 1 158 ? 170.709 174.955 225.517 1.00 52.67  ? 179 PRO C CB  1 
ATOM   8167  C CG  . PRO C 1 158 ? 170.357 173.950 224.515 1.00 52.67  ? 179 PRO C CG  1 
ATOM   8168  C CD  . PRO C 1 158 ? 169.401 174.676 223.638 1.00 52.67  ? 179 PRO C CD  1 
ATOM   8169  N N   . LYS C 1 159 ? 169.468 178.069 225.246 1.00 58.92  ? 180 LYS C N   1 
ATOM   8170  C CA  . LYS C 1 159 ? 169.562 179.497 225.563 1.00 58.92  ? 180 LYS C CA  1 
ATOM   8171  C C   . LYS C 1 159 ? 168.174 180.101 225.807 1.00 58.92  ? 180 LYS C C   1 
ATOM   8172  O O   . LYS C 1 159 ? 167.786 181.156 225.300 1.00 58.92  ? 180 LYS C O   1 
ATOM   8173  C CB  . LYS C 1 159 ? 170.357 180.218 224.469 1.00 58.92  ? 180 LYS C CB  1 
ATOM   8174  C CG  . LYS C 1 159 ? 169.780 180.178 223.047 1.00 58.92  ? 180 LYS C CG  1 
ATOM   8175  C CD  . LYS C 1 159 ? 170.660 180.936 222.074 1.00 58.92  ? 180 LYS C CD  1 
ATOM   8176  C CE  . LYS C 1 159 ? 171.936 180.160 221.796 1.00 58.92  ? 180 LYS C CE  1 
ATOM   8177  N NZ  . LYS C 1 159 ? 172.761 180.805 220.739 1.00 58.92  ? 180 LYS C NZ  1 
ATOM   8178  N N   . ILE C 1 160 ? 167.438 179.439 226.696 1.00 55.95  ? 181 ILE C N   1 
ATOM   8179  C CA  . ILE C 1 160 ? 166.075 179.862 226.994 1.00 55.95  ? 181 ILE C CA  1 
ATOM   8180  C C   . ILE C 1 160 ? 166.044 181.005 228.013 1.00 55.95  ? 181 ILE C C   1 
ATOM   8181  O O   . ILE C 1 160 ? 165.145 181.851 227.966 1.00 55.95  ? 181 ILE C O   1 
ATOM   8182  C CB  . ILE C 1 160 ? 165.243 178.640 227.448 1.00 55.95  ? 181 ILE C CB  1 
ATOM   8183  C CG1 . ILE C 1 160 ? 163.746 178.967 227.534 1.00 55.95  ? 181 ILE C CG1 1 
ATOM   8184  C CG2 . ILE C 1 160 ? 165.786 178.017 228.738 1.00 55.95  ? 181 ILE C CG2 1 
ATOM   8185  C CD1 . ILE C 1 160 ? 162.864 177.746 227.693 1.00 55.95  ? 181 ILE C CD1 1 
ATOM   8186  N N   . ASN C 1 161 ? 167.042 181.093 228.896 1.00 59.15  ? 182 ASN C N   1 
ATOM   8187  C CA  . ASN C 1 161 ? 167.086 182.146 229.899 1.00 59.15  ? 182 ASN C CA  1 
ATOM   8188  C C   . ASN C 1 161 ? 168.407 182.895 229.947 1.00 59.15  ? 182 ASN C C   1 
ATOM   8189  O O   . ASN C 1 161 ? 168.472 183.943 230.600 1.00 59.15  ? 182 ASN C O   1 
ATOM   8190  C CB  . ASN C 1 161 ? 166.793 181.573 231.293 1.00 59.15  ? 182 ASN C CB  1 
ATOM   8191  C CG  . ASN C 1 161 ? 165.322 181.285 231.503 1.00 59.15  ? 182 ASN C CG  1 
ATOM   8192  O OD1 . ASN C 1 161 ? 164.461 181.937 230.912 1.00 59.15  ? 182 ASN C OD1 1 
ATOM   8193  N ND2 . ASN C 1 161 ? 165.026 180.301 232.343 1.00 59.15  ? 182 ASN C ND2 1 
ATOM   8194  N N   . ILE C 1 162 ? 169.460 182.391 229.301 1.00 62.44  ? 183 ILE C N   1 
ATOM   8195  C CA  . ILE C 1 162 ? 170.723 183.121 229.247 1.00 62.44  ? 183 ILE C CA  1 
ATOM   8196  C C   . ILE C 1 162 ? 170.589 184.344 228.348 1.00 62.44  ? 183 ILE C C   1 
ATOM   8197  O O   . ILE C 1 162 ? 171.097 185.427 228.664 1.00 62.44  ? 183 ILE C O   1 
ATOM   8198  C CB  . ILE C 1 162 ? 171.854 182.187 228.778 1.00 62.44  ? 183 ILE C CB  1 
ATOM   8199  C CG1 . ILE C 1 162 ? 171.876 180.906 229.616 1.00 62.44  ? 183 ILE C CG1 1 
ATOM   8200  C CG2 . ILE C 1 162 ? 173.204 182.887 228.858 1.00 62.44  ? 183 ILE C CG2 1 
ATOM   8201  C CD1 . ILE C 1 162 ? 172.091 181.137 231.098 1.00 62.44  ? 183 ILE C CD1 1 
ATOM   8202  N N   . LEU C 1 163 ? 169.889 184.196 227.230 1.00 68.37  ? 184 LEU C N   1 
ATOM   8203  C CA  . LEU C 1 163 ? 169.711 185.257 226.252 1.00 68.37  ? 184 LEU C CA  1 
ATOM   8204  C C   . LEU C 1 163 ? 168.330 185.887 226.403 1.00 68.37  ? 184 LEU C C   1 
ATOM   8205  O O   . LEU C 1 163 ? 167.389 185.252 226.886 1.00 68.37  ? 184 LEU C O   1 
ATOM   8206  C CB  . LEU C 1 163 ? 169.899 184.705 224.838 1.00 68.37  ? 184 LEU C CB  1 
ATOM   8207  C CG  . LEU C 1 163 ? 170.295 185.652 223.709 1.00 68.37  ? 184 LEU C CG  1 
ATOM   8208  C CD1 . LEU C 1 163 ? 171.767 186.000 223.804 1.00 68.37  ? 184 LEU C CD1 1 
ATOM   8209  C CD2 . LEU C 1 163 ? 169.995 184.989 222.381 1.00 68.37  ? 184 LEU C CD2 1 
ATOM   8210  N N   . SER C 1 164 ? 168.224 187.151 225.997 1.00 77.05  ? 185 SER C N   1 
ATOM   8211  C CA  . SER C 1 164 ? 166.976 187.892 226.123 1.00 77.05  ? 185 SER C CA  1 
ATOM   8212  C C   . SER C 1 164 ? 165.932 187.378 225.136 1.00 77.05  ? 185 SER C C   1 
ATOM   8213  O O   . SER C 1 164 ? 166.261 186.874 224.060 1.00 77.05  ? 185 SER C O   1 
ATOM   8214  C CB  . SER C 1 164 ? 167.216 189.384 225.896 1.00 77.05  ? 185 SER C CB  1 
ATOM   8215  O OG  . SER C 1 164 ? 167.596 189.640 224.556 1.00 77.05  ? 185 SER C OG  1 
ATOM   8216  N N   . CYS C 1 165 ? 164.658 187.530 225.518 1.00 82.25  ? 186 CYS C N   1 
ATOM   8217  C CA  . CYS C 1 165 ? 163.554 186.928 224.772 1.00 82.25  ? 186 CYS C CA  1 
ATOM   8218  C C   . CYS C 1 165 ? 163.363 187.585 223.409 1.00 82.25  ? 186 CYS C C   1 
ATOM   8219  O O   . CYS C 1 165 ? 163.008 186.910 222.432 1.00 82.25  ? 186 CYS C O   1 
ATOM   8220  C CB  . CYS C 1 165 ? 162.267 187.018 225.592 1.00 82.25  ? 186 CYS C CB  1 
ATOM   8221  S SG  . CYS C 1 165 ? 162.350 186.218 227.213 1.00 82.25  ? 186 CYS C SG  1 
ATOM   8222  N N   . LYS C 1 166 ? 163.597 188.899 223.322 1.00 82.34  ? 187 LYS C N   1 
ATOM   8223  C CA  . LYS C 1 166 ? 163.501 189.583 222.036 1.00 82.34  ? 187 LYS C CA  1 
ATOM   8224  C C   . LYS C 1 166 ? 164.621 189.164 221.090 1.00 82.34  ? 187 LYS C C   1 
ATOM   8225  O O   . LYS C 1 166 ? 164.431 189.172 219.868 1.00 82.34  ? 187 LYS C O   1 
ATOM   8226  C CB  . LYS C 1 166 ? 163.497 191.100 222.243 1.00 82.34  ? 187 LYS C CB  1 
ATOM   8227  C CG  . LYS C 1 166 ? 164.719 191.654 222.960 1.00 82.34  ? 187 LYS C CG  1 
ATOM   8228  C CD  . LYS C 1 166 ? 164.618 193.161 223.136 1.00 82.34  ? 187 LYS C CD  1 
ATOM   8229  C CE  . LYS C 1 166 ? 165.798 193.707 223.925 1.00 82.34  ? 187 LYS C CE  1 
ATOM   8230  N NZ  . LYS C 1 166 ? 167.082 193.560 223.186 1.00 82.34  ? 187 LYS C NZ  1 
ATOM   8231  N N   . GLN C 1 167 ? 165.772 188.752 221.630 1.00 80.24  ? 188 GLN C N   1 
ATOM   8232  C CA  . GLN C 1 167 ? 166.845 188.252 220.778 1.00 80.24  ? 188 GLN C CA  1 
ATOM   8233  C C   . GLN C 1 167 ? 166.499 186.880 220.207 1.00 80.24  ? 188 GLN C C   1 
ATOM   8234  O O   . GLN C 1 167 ? 166.807 186.596 219.043 1.00 80.24  ? 188 GLN C O   1 
ATOM   8235  C CB  . GLN C 1 167 ? 168.158 188.205 221.559 1.00 80.24  ? 188 GLN C CB  1 
ATOM   8236  C CG  . GLN C 1 167 ? 169.432 188.254 220.707 1.00 80.24  ? 188 GLN C CG  1 
ATOM   8237  C CD  . GLN C 1 167 ? 169.681 189.604 220.043 1.00 80.24  ? 188 GLN C CD  1 
ATOM   8238  O OE1 . GLN C 1 167 ? 169.036 189.963 219.056 1.00 80.24  ? 188 GLN C OE1 1 
ATOM   8239  N NE2 . GLN C 1 167 ? 170.624 190.359 220.592 1.00 80.24  ? 188 GLN C NE2 1 
ATOM   8240  N N   . LEU C 1 168 ? 165.848 186.024 221.008 1.00 72.94  ? 189 LEU C N   1 
ATOM   8241  C CA  . LEU C 1 168 ? 165.329 184.760 220.487 1.00 72.94  ? 189 LEU C CA  1 
ATOM   8242  C C   . LEU C 1 168 ? 164.245 184.990 219.444 1.00 72.94  ? 189 LEU C C   1 
ATOM   8243  O O   . LEU C 1 168 ? 164.177 184.260 218.449 1.00 72.94  ? 189 LEU C O   1 
ATOM   8244  C CB  . LEU C 1 168 ? 164.785 183.876 221.612 1.00 72.94  ? 189 LEU C CB  1 
ATOM   8245  C CG  . LEU C 1 168 ? 165.704 182.948 222.415 1.00 72.94  ? 189 LEU C CG  1 
ATOM   8246  C CD1 . LEU C 1 168 ? 166.606 183.686 223.375 1.00 72.94  ? 189 LEU C CD1 1 
ATOM   8247  C CD2 . LEU C 1 168 ? 164.869 181.915 223.160 1.00 72.94  ? 189 LEU C CD2 1 
ATOM   8248  N N   . SER C 1 169 ? 163.388 185.997 219.657 1.00 72.97  ? 190 SER C N   1 
ATOM   8249  C CA  . SER C 1 169 ? 162.361 186.330 218.670 1.00 72.97  ? 190 SER C CA  1 
ATOM   8250  C C   . SER C 1 169 ? 162.976 186.807 217.356 1.00 72.97  ? 190 SER C C   1 
ATOM   8251  O O   . SER C 1 169 ? 162.537 186.397 216.273 1.00 72.97  ? 190 SER C O   1 
ATOM   8252  C CB  . SER C 1 169 ? 161.419 187.392 219.235 1.00 72.97  ? 190 SER C CB  1 
ATOM   8253  O OG  . SER C 1 169 ? 160.444 187.770 218.278 1.00 72.97  ? 190 SER C OG  1 
ATOM   8254  N N   . ASN C 1 170 ? 164.012 187.648 217.438 1.00 70.23  ? 191 ASN C N   1 
ATOM   8255  C CA  . ASN C 1 170 ? 164.690 188.136 216.239 1.00 70.23  ? 191 ASN C CA  1 
ATOM   8256  C C   . ASN C 1 170 ? 165.427 187.015 215.511 1.00 70.23  ? 191 ASN C C   1 
ATOM   8257  O O   . ASN C 1 170 ? 165.389 186.943 214.276 1.00 70.23  ? 191 ASN C O   1 
ATOM   8258  C CB  . ASN C 1 170 ? 165.656 189.259 216.613 1.00 70.23  ? 191 ASN C CB  1 
ATOM   8259  C CG  . ASN C 1 170 ? 166.024 190.133 215.430 1.00 70.23  ? 191 ASN C CG  1 
ATOM   8260  O OD1 . ASN C 1 170 ? 165.538 189.932 214.318 1.00 70.23  ? 191 ASN C OD1 1 
ATOM   8261  N ND2 . ASN C 1 170 ? 166.888 191.113 215.667 1.00 70.23  ? 191 ASN C ND2 1 
ATOM   8262  N N   . THR C 1 171 ? 166.092 186.127 216.261 1.00 58.33  ? 192 THR C N   1 
ATOM   8263  C CA  . THR C 1 171 ? 166.805 185.006 215.652 1.00 58.33  ? 192 THR C CA  1 
ATOM   8264  C C   . THR C 1 171 ? 165.838 184.019 215.005 1.00 58.33  ? 192 THR C C   1 
ATOM   8265  O O   . THR C 1 171 ? 166.107 183.504 213.910 1.00 58.33  ? 192 THR C O   1 
ATOM   8266  C CB  . THR C 1 171 ? 167.671 184.313 216.706 1.00 58.33  ? 192 THR C CB  1 
ATOM   8267  O OG1 . THR C 1 171 ? 168.490 185.288 217.364 1.00 58.33  ? 192 THR C OG1 1 
ATOM   8268  C CG2 . THR C 1 171 ? 168.576 183.268 216.069 1.00 58.33  ? 192 THR C CG2 1 
ATOM   8269  N N   . LEU C 1 172 ? 164.694 183.769 215.654 1.00 53.80  ? 193 LEU C N   1 
ATOM   8270  C CA  . LEU C 1 172 ? 163.665 182.910 215.081 1.00 53.80  ? 193 LEU C CA  1 
ATOM   8271  C C   . LEU C 1 172 ? 163.063 183.523 213.824 1.00 53.80  ? 193 LEU C C   1 
ATOM   8272  O O   . LEU C 1 172 ? 162.783 182.806 212.858 1.00 53.80  ? 193 LEU C O   1 
ATOM   8273  C CB  . LEU C 1 172 ? 162.576 182.637 216.117 1.00 53.80  ? 193 LEU C CB  1 
ATOM   8274  C CG  . LEU C 1 172 ? 161.544 181.560 215.778 1.00 53.80  ? 193 LEU C CG  1 
ATOM   8275  C CD1 . LEU C 1 172 ? 162.223 180.284 215.310 1.00 53.80  ? 193 LEU C CD1 1 
ATOM   8276  C CD2 . LEU C 1 172 ? 160.649 181.286 216.974 1.00 53.80  ? 193 LEU C CD2 1 
ATOM   8277  N N   . ASN C 1 173 ? 162.874 184.848 213.812 1.00 46.67  ? 194 ASN C N   1 
ATOM   8278  C CA  . ASN C 1 173 ? 162.371 185.522 212.617 1.00 46.67  ? 194 ASN C CA  1 
ATOM   8279  C C   . ASN C 1 173 ? 163.366 185.447 211.463 1.00 46.67  ? 194 ASN C C   1 
ATOM   8280  O O   . ASN C 1 173 ? 162.967 185.212 210.317 1.00 46.67  ? 194 ASN C O   1 
ATOM   8281  C CB  . ASN C 1 173 ? 162.030 186.975 212.939 1.00 46.67  ? 194 ASN C CB  1 
ATOM   8282  C CG  . ASN C 1 173 ? 160.675 187.121 213.596 1.00 46.67  ? 194 ASN C CG  1 
ATOM   8283  O OD1 . ASN C 1 173 ? 159.702 186.494 213.178 1.00 46.67  ? 194 ASN C OD1 1 
ATOM   8284  N ND2 . ASN C 1 173 ? 160.603 187.949 214.631 1.00 46.67  ? 194 ASN C ND2 1 
ATOM   8285  N N   . ILE C 1 174 ? 164.662 185.625 211.750 1.00 40.32  ? 195 ILE C N   1 
ATOM   8286  C CA  . ILE C 1 174 ? 165.691 185.528 210.713 1.00 40.32  ? 195 ILE C CA  1 
ATOM   8287  C C   . ILE C 1 174 ? 165.767 184.109 210.150 1.00 40.32  ? 195 ILE C C   1 
ATOM   8288  O O   . ILE C 1 174 ? 165.820 183.913 208.925 1.00 40.32  ? 195 ILE C O   1 
ATOM   8289  C CB  . ILE C 1 174 ? 167.047 186.005 211.273 1.00 40.32  ? 195 ILE C CB  1 
ATOM   8290  C CG1 . ILE C 1 174 ? 167.048 187.522 211.486 1.00 40.32  ? 195 ILE C CG1 1 
ATOM   8291  C CG2 . ILE C 1 174 ? 168.203 185.613 210.362 1.00 40.32  ? 195 ILE C CG2 1 
ATOM   8292  C CD1 . ILE C 1 174 ? 166.554 188.325 210.297 1.00 40.32  ? 195 ILE C CD1 1 
ATOM   8293  N N   . MET C 1 175 ? 165.722 183.102 211.033 1.00 38.07  ? 196 MET C N   1 
ATOM   8294  C CA  . MET C 1 175 ? 165.766 181.707 210.599 1.00 38.07  ? 196 MET C CA  1 
ATOM   8295  C C   . MET C 1 175 ? 164.524 181.325 209.797 1.00 38.07  ? 196 MET C C   1 
ATOM   8296  O O   . MET C 1 175 ? 164.628 180.617 208.789 1.00 38.07  ? 196 MET C O   1 
ATOM   8297  C CB  . MET C 1 175 ? 165.924 180.792 211.813 1.00 38.07  ? 196 MET C CB  1 
ATOM   8298  C CG  . MET C 1 175 ? 166.107 179.324 211.473 1.00 38.07  ? 196 MET C CG  1 
ATOM   8299  S SD  . MET C 1 175 ? 166.297 178.297 212.941 1.00 38.07  ? 196 MET C SD  1 
ATOM   8300  C CE  . MET C 1 175 ? 167.939 178.768 213.473 1.00 38.07  ? 196 MET C CE  1 
ATOM   8301  N N   . LEU C 1 176 ? 163.347 181.813 210.206 1.00 35.65  ? 197 LEU C N   1 
ATOM   8302  C CA  . LEU C 1 176 ? 162.125 181.503 209.472 1.00 35.65  ? 197 LEU C CA  1 
ATOM   8303  C C   . LEU C 1 176 ? 162.067 182.207 208.123 1.00 35.65  ? 197 LEU C C   1 
ATOM   8304  O O   . LEU C 1 176 ? 161.555 181.630 207.161 1.00 35.65  ? 197 LEU C O   1 
ATOM   8305  C CB  . LEU C 1 176 ? 160.897 181.859 210.309 1.00 35.65  ? 197 LEU C CB  1 
ATOM   8306  C CG  . LEU C 1 176 ? 160.517 180.841 211.385 1.00 35.65  ? 197 LEU C CG  1 
ATOM   8307  C CD1 . LEU C 1 176 ? 159.384 181.374 212.243 1.00 35.65  ? 197 LEU C CD1 1 
ATOM   8308  C CD2 . LEU C 1 176 ? 160.134 179.514 210.753 1.00 35.65  ? 197 LEU C CD2 1 
ATOM   8309  N N   . LEU C 1 177 ? 162.585 183.437 208.024 1.00 28.14  ? 198 LEU C N   1 
ATOM   8310  C CA  . LEU C 1 177 ? 162.644 184.103 206.723 1.00 28.14  ? 198 LEU C CA  1 
ATOM   8311  C C   . LEU C 1 177 ? 163.628 183.416 205.780 1.00 28.14  ? 198 LEU C C   1 
ATOM   8312  O O   . LEU C 1 177 ? 163.341 183.265 204.583 1.00 28.14  ? 198 LEU C O   1 
ATOM   8313  C CB  . LEU C 1 177 ? 162.994 185.583 206.893 1.00 28.14  ? 198 LEU C CB  1 
ATOM   8314  C CG  . LEU C 1 177 ? 161.852 186.608 206.980 1.00 28.14  ? 198 LEU C CG  1 
ATOM   8315  C CD1 . LEU C 1 177 ? 161.121 186.647 205.655 1.00 28.14  ? 198 LEU C CD1 1 
ATOM   8316  C CD2 . LEU C 1 177 ? 160.856 186.352 208.103 1.00 28.14  ? 198 LEU C CD2 1 
ATOM   8317  N N   . GLN C 1 178 ? 164.780 182.972 206.304 1.00 25.14  ? 199 GLN C N   1 
ATOM   8318  C CA  . GLN C 1 178 ? 165.732 182.223 205.483 1.00 25.14  ? 199 GLN C CA  1 
ATOM   8319  C C   . GLN C 1 178 ? 165.147 180.888 205.029 1.00 25.14  ? 199 GLN C C   1 
ATOM   8320  O O   . GLN C 1 178 ? 165.309 180.487 203.866 1.00 25.14  ? 199 GLN C O   1 
ATOM   8321  C CB  . GLN C 1 178 ? 167.033 182.012 206.260 1.00 25.14  ? 199 GLN C CB  1 
ATOM   8322  C CG  . GLN C 1 178 ? 168.209 181.557 205.413 1.00 25.14  ? 199 GLN C CG  1 
ATOM   8323  C CD  . GLN C 1 178 ? 168.387 180.053 205.418 1.00 25.14  ? 199 GLN C CD  1 
ATOM   8324  O OE1 . GLN C 1 178 ? 168.041 179.380 206.387 1.00 25.14  ? 199 GLN C OE1 1 
ATOM   8325  N NE2 . GLN C 1 178 ? 168.932 179.518 204.332 1.00 25.14  ? 199 GLN C NE2 1 
ATOM   8326  N N   . TYR C 1 179 ? 164.420 180.208 205.918 1.00 25.07  ? 200 TYR C N   1 
ATOM   8327  C CA  . TYR C 1 179 ? 163.797 178.947 205.536 1.00 25.07  ? 200 TYR C CA  1 
ATOM   8328  C C   . TYR C 1 179 ? 162.652 179.155 204.552 1.00 25.07  ? 200 TYR C C   1 
ATOM   8329  O O   . TYR C 1 179 ? 162.477 178.335 203.650 1.00 25.07  ? 200 TYR C O   1 
ATOM   8330  C CB  . TYR C 1 179 ? 163.326 178.196 206.780 1.00 25.07  ? 200 TYR C CB  1 
ATOM   8331  C CG  . TYR C 1 179 ? 162.832 176.798 206.495 1.00 25.07  ? 200 TYR C CG  1 
ATOM   8332  C CD1 . TYR C 1 179 ? 163.546 175.950 205.656 1.00 25.07  ? 200 TYR C CD1 1 
ATOM   8333  C CD2 . TYR C 1 179 ? 161.680 176.309 207.101 1.00 25.07  ? 200 TYR C CD2 1 
ATOM   8334  C CE1 . TYR C 1 179 ? 163.109 174.664 205.402 1.00 25.07  ? 200 TYR C CE1 1 
ATOM   8335  C CE2 . TYR C 1 179 ? 161.238 175.021 206.857 1.00 25.07  ? 200 TYR C CE2 1 
ATOM   8336  C CZ  . TYR C 1 179 ? 161.957 174.205 206.006 1.00 25.07  ? 200 TYR C CZ  1 
ATOM   8337  O OH  . TYR C 1 179 ? 161.522 172.925 205.756 1.00 25.07  ? 200 TYR C OH  1 
ATOM   8338  N N   . TYR C 1 180 ? 161.892 180.250 204.685 1.00 22.00  ? 201 TYR C N   1 
ATOM   8339  C CA  . TYR C 1 180 ? 160.848 180.562 203.711 1.00 22.00  ? 201 TYR C CA  1 
ATOM   8340  C C   . TYR C 1 180 ? 161.447 180.864 202.345 1.00 22.00  ? 201 TYR C C   1 
ATOM   8341  O O   . TYR C 1 180 ? 160.872 180.499 201.311 1.00 22.00  ? 201 TYR C O   1 
ATOM   8342  C CB  . TYR C 1 180 ? 160.005 181.737 204.203 1.00 22.00  ? 201 TYR C CB  1 
ATOM   8343  C CG  . TYR C 1 180 ? 159.049 182.276 203.165 1.00 22.00  ? 201 TYR C CG  1 
ATOM   8344  C CD1 . TYR C 1 180 ? 157.935 181.543 202.779 1.00 22.00  ? 201 TYR C CD1 1 
ATOM   8345  C CD2 . TYR C 1 180 ? 159.254 183.521 202.580 1.00 22.00  ? 201 TYR C CD2 1 
ATOM   8346  C CE1 . TYR C 1 180 ? 157.056 182.030 201.830 1.00 22.00  ? 201 TYR C CE1 1 
ATOM   8347  C CE2 . TYR C 1 180 ? 158.381 184.015 201.633 1.00 22.00  ? 201 TYR C CE2 1 
ATOM   8348  C CZ  . TYR C 1 180 ? 157.284 183.266 201.263 1.00 22.00  ? 201 TYR C CZ  1 
ATOM   8349  O OH  . TYR C 1 180 ? 156.415 183.759 200.318 1.00 22.00  ? 201 TYR C OH  1 
ATOM   8350  N N   . SER C 1 181 ? 162.626 181.493 202.323 1.00 19.87  ? 202 SER C N   1 
ATOM   8351  C CA  . SER C 1 181 ? 163.363 181.625 201.071 1.00 19.87  ? 202 SER C CA  1 
ATOM   8352  C C   . SER C 1 181 ? 163.831 180.271 200.540 1.00 19.87  ? 202 SER C C   1 
ATOM   8353  O O   . SER C 1 181 ? 164.000 180.110 199.326 1.00 19.87  ? 202 SER C O   1 
ATOM   8354  C CB  . SER C 1 181 ? 164.557 182.558 201.260 1.00 19.87  ? 202 SER C CB  1 
ATOM   8355  O OG  . SER C 1 181 ? 165.418 182.503 200.139 1.00 19.87  ? 202 SER C OG  1 
ATOM   8356  N N   . GLN C 1 182 ? 164.055 179.294 201.425 1.00 23.31  ? 203 GLN C N   1 
ATOM   8357  C CA  . GLN C 1 182 ? 164.431 177.958 200.953 1.00 23.31  ? 203 GLN C CA  1 
ATOM   8358  C C   . GLN C 1 182 ? 163.244 177.187 200.366 1.00 23.31  ? 203 GLN C C   1 
ATOM   8359  O O   . GLN C 1 182 ? 163.421 176.425 199.408 1.00 23.31  ? 203 GLN C O   1 
ATOM   8360  C CB  . GLN C 1 182 ? 165.097 177.159 202.072 1.00 23.31  ? 203 GLN C CB  1 
ATOM   8361  C CG  . GLN C 1 182 ? 166.451 177.706 202.478 1.00 23.31  ? 203 GLN C CG  1 
ATOM   8362  C CD  . GLN C 1 182 ? 167.588 177.062 201.710 1.00 23.31  ? 203 GLN C CD  1 
ATOM   8363  O OE1 . GLN C 1 182 ? 167.624 177.101 200.480 1.00 23.31  ? 203 GLN C OE1 1 
ATOM   8364  N NE2 . GLN C 1 182 ? 168.526 176.465 202.434 1.00 23.31  ? 203 GLN C NE2 1 
ATOM   8365  N N   . ILE C 1 183 ? 162.042 177.328 200.945 1.00 15.25  ? 204 ILE C N   1 
ATOM   8366  C CA  . ILE C 1 183 ? 160.840 176.805 200.274 1.00 15.25  ? 204 ILE C CA  1 
ATOM   8367  C C   . ILE C 1 183 ? 160.595 177.514 198.944 1.00 15.25  ? 204 ILE C C   1 
ATOM   8368  O O   . ILE C 1 183 ? 160.318 176.862 197.928 1.00 15.25  ? 204 ILE C O   1 
ATOM   8369  C CB  . ILE C 1 183 ? 159.581 176.817 201.182 1.00 15.25  ? 204 ILE C CB  1 
ATOM   8370  C CG1 . ILE C 1 183 ? 159.634 175.764 202.301 1.00 15.25  ? 204 ILE C CG1 1 
ATOM   8371  C CG2 . ILE C 1 183 ? 158.276 176.661 200.399 1.00 15.25  ? 204 ILE C CG2 1 
ATOM   8372  C CD1 . ILE C 1 183 ? 160.194 176.144 203.587 1.00 15.25  ? 204 ILE C CD1 1 
ATOM   8373  N N   . LEU C 1 184 ? 160.772 178.839 198.897 1.00 22.49  ? 205 LEU C N   1 
ATOM   8374  C CA  . LEU C 1 184 ? 160.509 179.547 197.629 1.00 22.49  ? 205 LEU C CA  1 
ATOM   8375  C C   . LEU C 1 184 ? 161.565 179.276 196.501 1.00 22.49  ? 205 LEU C C   1 
ATOM   8376  O O   . LEU C 1 184 ? 161.492 179.962 195.472 1.00 22.49  ? 205 LEU C O   1 
ATOM   8377  C CB  . LEU C 1 184 ? 160.404 181.051 197.876 1.00 22.49  ? 205 LEU C CB  1 
ATOM   8378  C CG  . LEU C 1 184 ? 158.990 181.608 198.046 1.00 22.49  ? 205 LEU C CG  1 
ATOM   8379  C CD1 . LEU C 1 184 ? 159.033 183.121 198.143 1.00 22.49  ? 205 LEU C CD1 1 
ATOM   8380  C CD2 . LEU C 1 184 ? 158.091 181.170 196.901 1.00 22.49  ? 205 LEU C CD2 1 
ATOM   8381  N N   . THR C 1 185 ? 162.504 178.341 196.644 1.00 22.21  ? 206 THR C N   1 
ATOM   8382  C CA  . THR C 1 185 ? 163.399 177.929 195.572 1.00 22.21  ? 206 THR C CA  1 
ATOM   8383  C C   . THR C 1 185 ? 163.073 176.538 195.046 1.00 22.21  ? 206 THR C C   1 
ATOM   8384  O O   . THR C 1 185 ? 162.967 176.348 193.830 1.00 22.21  ? 206 THR C O   1 
ATOM   8385  C CB  . THR C 1 185 ? 164.855 177.975 196.061 1.00 22.21  ? 206 THR C CB  1 
ATOM   8386  O OG1 . THR C 1 185 ? 165.161 179.295 196.524 1.00 22.21  ? 206 THR C OG1 1 
ATOM   8387  C CG2 . THR C 1 185 ? 165.816 177.611 194.940 1.00 22.21  ? 206 THR C CG2 1 
ATOM   8388  N N   . VAL C 1 186 ? 162.903 175.557 195.939 1.00 23.28  ? 207 VAL C N   1 
ATOM   8389  C CA  . VAL C 1 186 ? 162.631 174.186 195.507 1.00 23.28  ? 207 VAL C CA  1 
ATOM   8390  C C   . VAL C 1 186 ? 161.214 174.049 194.944 1.00 23.28  ? 207 VAL C C   1 
ATOM   8391  O O   . VAL C 1 186 ? 161.015 173.436 193.887 1.00 23.28  ? 207 VAL C O   1 
ATOM   8392  C CB  . VAL C 1 186 ? 162.931 173.193 196.654 1.00 23.28  ? 207 VAL C CB  1 
ATOM   8393  C CG1 . VAL C 1 186 ? 162.234 173.575 197.957 1.00 23.28  ? 207 VAL C CG1 1 
ATOM   8394  C CG2 . VAL C 1 186 ? 162.538 171.778 196.254 1.00 23.28  ? 207 VAL C CG2 1 
ATOM   8395  N N   . PHE C 1 187 ? 160.219 174.643 195.595 1.00 22.34  ? 208 PHE C N   1 
ATOM   8396  C CA  . PHE C 1 187 ? 158.846 174.608 195.089 1.00 22.34  ? 208 PHE C CA  1 
ATOM   8397  C C   . PHE C 1 187 ? 158.546 175.829 194.229 1.00 22.34  ? 208 PHE C C   1 
ATOM   8398  O O   . PHE C 1 187 ? 157.558 176.534 194.426 1.00 22.34  ? 208 PHE C O   1 
ATOM   8399  C CB  . PHE C 1 187 ? 157.860 174.490 196.245 1.00 22.34  ? 208 PHE C CB  1 
ATOM   8400  C CG  . PHE C 1 187 ? 157.991 173.212 197.025 1.00 22.34  ? 208 PHE C CG  1 
ATOM   8401  C CD1 . PHE C 1 187 ? 157.487 172.023 196.520 1.00 22.34  ? 208 PHE C CD1 1 
ATOM   8402  C CD2 . PHE C 1 187 ? 158.614 173.197 198.262 1.00 22.34  ? 208 PHE C CD2 1 
ATOM   8403  C CE1 . PHE C 1 187 ? 157.604 170.843 197.234 1.00 22.34  ? 208 PHE C CE1 1 
ATOM   8404  C CE2 . PHE C 1 187 ? 158.736 172.019 198.982 1.00 22.34  ? 208 PHE C CE2 1 
ATOM   8405  C CZ  . PHE C 1 187 ? 158.229 170.843 198.466 1.00 22.34  ? 208 PHE C CZ  1 
ATOM   8406  N N   . GLY C 1 188 ? 159.415 176.083 193.254 1.00 31.78  ? 209 GLY C N   1 
ATOM   8407  C CA  . GLY C 1 188 ? 159.251 177.179 192.330 1.00 31.78  ? 209 GLY C CA  1 
ATOM   8408  C C   . GLY C 1 188 ? 158.445 176.820 191.096 1.00 31.78  ? 209 GLY C C   1 
ATOM   8409  O O   . GLY C 1 188 ? 157.394 177.413 190.832 1.00 31.78  ? 209 GLY C O   1 
ATOM   8410  N N   . PRO C 1 189 ? 158.925 175.851 190.303 1.00 38.21  ? 210 PRO C N   1 
ATOM   8411  C CA  . PRO C 1 189 ? 158.119 175.369 189.168 1.00 38.21  ? 210 PRO C CA  1 
ATOM   8412  C C   . PRO C 1 189 ? 156.848 174.635 189.565 1.00 38.21  ? 210 PRO C C   1 
ATOM   8413  O O   . PRO C 1 189 ? 155.962 174.477 188.716 1.00 38.21  ? 210 PRO C O   1 
ATOM   8414  C CB  . PRO C 1 189 ? 159.086 174.437 188.427 1.00 38.21  ? 210 PRO C CB  1 
ATOM   8415  C CG  . PRO C 1 189 ? 160.419 175.008 188.722 1.00 38.21  ? 210 PRO C CG  1 
ATOM   8416  C CD  . PRO C 1 189 ? 160.336 175.443 190.159 1.00 38.21  ? 210 PRO C CD  1 
ATOM   8417  N N   . ASN C 1 190 ? 156.726 174.176 190.814 1.00 32.12  ? 211 ASN C N   1 
ATOM   8418  C CA  . ASN C 1 190 ? 155.501 173.517 191.252 1.00 32.12  ? 211 ASN C CA  1 
ATOM   8419  C C   . ASN C 1 190 ? 154.330 174.478 191.393 1.00 32.12  ? 211 ASN C C   1 
ATOM   8420  O O   . ASN C 1 190 ? 153.181 174.029 191.398 1.00 32.12  ? 211 ASN C O   1 
ATOM   8421  C CB  . ASN C 1 190 ? 155.723 172.804 192.583 1.00 32.12  ? 211 ASN C CB  1 
ATOM   8422  C CG  . ASN C 1 190 ? 156.106 171.356 192.409 1.00 32.12  ? 211 ASN C CG  1 
ATOM   8423  O OD1 . ASN C 1 190 ? 156.014 170.803 191.315 1.00 32.12  ? 211 ASN C OD1 1 
ATOM   8424  N ND2 . ASN C 1 190 ? 156.523 170.726 193.496 1.00 32.12  ? 211 ASN C ND2 1 
ATOM   8425  N N   . LEU C 1 191 ? 154.586 175.782 191.512 1.00 40.89  ? 212 LEU C N   1 
ATOM   8426  C CA  . LEU C 1 191 ? 153.495 176.734 191.675 1.00 40.89  ? 212 LEU C CA  1 
ATOM   8427  C C   . LEU C 1 191 ? 152.697 176.935 190.393 1.00 40.89  ? 212 LEU C C   1 
ATOM   8428  O O   . LEU C 1 191 ? 151.540 177.361 190.465 1.00 40.89  ? 212 LEU C O   1 
ATOM   8429  C CB  . LEU C 1 191 ? 154.038 178.073 192.172 1.00 40.89  ? 212 LEU C CB  1 
ATOM   8430  C CG  . LEU C 1 191 ? 154.647 178.068 193.574 1.00 40.89  ? 212 LEU C CG  1 
ATOM   8431  C CD1 . LEU C 1 191 ? 155.614 179.227 193.747 1.00 40.89  ? 212 LEU C CD1 1 
ATOM   8432  C CD2 . LEU C 1 191 ? 153.552 178.118 194.625 1.00 40.89  ? 212 LEU C CD2 1 
ATOM   8433  N N   . ARG C 1 192 ? 153.283 176.632 189.232 1.00 46.17  ? 213 ARG C N   1 
ATOM   8434  C CA  . ARG C 1 192 ? 152.561 176.766 187.970 1.00 46.17  ? 213 ARG C CA  1 
ATOM   8435  C C   . ARG C 1 192 ? 151.454 175.723 187.851 1.00 46.17  ? 213 ARG C C   1 
ATOM   8436  O O   . ARG C 1 192 ? 150.309 176.052 187.518 1.00 46.17  ? 213 ARG C O   1 
ATOM   8437  C CB  . ARG C 1 192 ? 153.534 176.650 186.797 1.00 46.17  ? 213 ARG C CB  1 
ATOM   8438  C CG  . ARG C 1 192 ? 152.859 176.611 185.433 1.00 46.17  ? 213 ARG C CG  1 
ATOM   8439  C CD  . ARG C 1 192 ? 153.825 176.828 184.265 1.00 46.17  ? 213 ARG C CD  1 
ATOM   8440  N NE  . ARG C 1 192 ? 154.860 175.803 184.160 1.00 46.17  ? 213 ARG C NE  1 
ATOM   8441  C CZ  . ARG C 1 192 ? 156.112 175.947 184.573 1.00 46.17  ? 213 ARG C CZ  1 
ATOM   8442  N NH1 . ARG C 1 192 ? 156.532 177.071 185.130 1.00 46.17  ? 213 ARG C NH1 1 
ATOM   8443  N NH2 . ARG C 1 192 ? 156.964 174.936 184.424 1.00 46.17  ? 213 ARG C NH2 1 
ATOM   8444  N N   . ASP C 1 193 ? 151.775 174.461 188.128 1.00 42.85  ? 214 ASP C N   1 
ATOM   8445  C CA  . ASP C 1 193 ? 150.808 173.368 188.031 1.00 42.85  ? 214 ASP C CA  1 
ATOM   8446  C C   . ASP C 1 193 ? 151.262 172.267 188.978 1.00 42.85  ? 214 ASP C C   1 
ATOM   8447  O O   . ASP C 1 193 ? 152.100 171.427 188.614 1.00 42.85  ? 214 ASP C O   1 
ATOM   8448  C CB  . ASP C 1 193 ? 150.688 172.848 186.601 1.00 42.85  ? 214 ASP C CB  1 
ATOM   8449  C CG  . ASP C 1 193 ? 149.598 171.809 186.449 1.00 42.85  ? 214 ASP C CG  1 
ATOM   8450  O OD1 . ASP C 1 193 ? 148.644 171.823 187.254 1.00 42.85  ? 214 ASP C OD1 1 
ATOM   8451  O OD2 . ASP C 1 193 ? 149.695 170.977 185.523 1.00 42.85  ? 214 ASP C OD2 1 
ATOM   8452  N N   . PRO C 1 194 ? 150.725 172.224 190.206 1.00 33.05  ? 215 PRO C N   1 
ATOM   8453  C CA  . PRO C 1 194 ? 151.277 171.314 191.219 1.00 33.05  ? 215 PRO C CA  1 
ATOM   8454  C C   . PRO C 1 194 ? 150.746 169.892 191.158 1.00 33.05  ? 215 PRO C C   1 
ATOM   8455  O O   . PRO C 1 194 ? 150.458 169.300 192.201 1.00 33.05  ? 215 PRO C O   1 
ATOM   8456  C CB  . PRO C 1 194 ? 150.862 171.984 192.531 1.00 33.05  ? 215 PRO C CB  1 
ATOM   8457  C CG  . PRO C 1 194 ? 149.559 172.624 192.194 1.00 33.05  ? 215 PRO C CG  1 
ATOM   8458  C CD  . PRO C 1 194 ? 149.683 173.103 190.767 1.00 33.05  ? 215 PRO C CD  1 
ATOM   8459  N N   . ALA C 1 195 ? 150.625 169.323 189.963 1.00 27.70  ? 216 ALA C N   1 
ATOM   8460  C CA  . ALA C 1 195 ? 150.255 167.919 189.830 1.00 27.70  ? 216 ALA C CA  1 
ATOM   8461  C C   . ALA C 1 195 ? 151.074 167.160 188.802 1.00 27.70  ? 216 ALA C C   1 
ATOM   8462  O O   . ALA C 1 195 ? 151.142 165.930 188.888 1.00 27.70  ? 216 ALA C O   1 
ATOM   8463  C CB  . ALA C 1 195 ? 148.770 167.784 189.475 1.00 27.70  ? 216 ALA C CB  1 
ATOM   8464  N N   . THR C 1 196 ? 151.697 167.834 187.836 1.00 35.73  ? 217 THR C N   1 
ATOM   8465  C CA  . THR C 1 196 ? 152.407 167.182 186.747 1.00 35.73  ? 217 THR C CA  1 
ATOM   8466  C C   . THR C 1 196 ? 153.909 167.416 186.791 1.00 35.73  ? 217 THR C C   1 
ATOM   8467  O O   . THR C 1 196 ? 154.639 166.806 186.004 1.00 35.73  ? 217 THR C O   1 
ATOM   8468  C CB  . THR C 1 196 ? 151.862 167.666 185.399 1.00 35.73  ? 217 THR C CB  1 
ATOM   8469  O OG1 . THR C 1 196 ? 152.309 169.007 185.160 1.00 35.73  ? 217 THR C OG1 1 
ATOM   8470  C CG2 . THR C 1 196 ? 150.342 167.648 185.397 1.00 35.73  ? 217 THR C CG2 1 
ATOM   8471  N N   . VAL C 1 197 ? 154.389 168.277 187.678 1.00 28.58  ? 218 VAL C N   1 
ATOM   8472  C CA  . VAL C 1 197 ? 155.803 168.634 187.752 1.00 28.58  ? 218 VAL C CA  1 
ATOM   8473  C C   . VAL C 1 197 ? 156.439 167.819 188.873 1.00 28.58  ? 218 VAL C C   1 
ATOM   8474  O O   . VAL C 1 197 ? 156.047 167.984 190.038 1.00 28.58  ? 218 VAL C O   1 
ATOM   8475  C CB  . VAL C 1 197 ? 155.993 170.139 187.989 1.00 28.58  ? 218 VAL C CB  1 
ATOM   8476  C CG1 . VAL C 1 197 ? 157.467 170.463 188.158 1.00 28.58  ? 218 VAL C CG1 1 
ATOM   8477  C CG2 . VAL C 1 197 ? 155.398 170.932 186.838 1.00 28.58  ? 218 VAL C CG2 1 
ATOM   8478  N N   . PRO C 1 198 ? 157.396 166.947 188.581 1.00 23.05  ? 219 PRO C N   1 
ATOM   8479  C CA  . PRO C 1 198 ? 158.039 166.161 189.635 1.00 23.05  ? 219 PRO C CA  1 
ATOM   8480  C C   . PRO C 1 198 ? 159.109 166.969 190.358 1.00 23.05  ? 219 PRO C C   1 
ATOM   8481  O O   . PRO C 1 198 ? 159.507 168.055 189.936 1.00 23.05  ? 219 PRO C O   1 
ATOM   8482  C CB  . PRO C 1 198 ? 158.651 164.990 188.866 1.00 23.05  ? 219 PRO C CB  1 
ATOM   8483  C CG  . PRO C 1 198 ? 158.997 165.582 187.544 1.00 23.05  ? 219 PRO C CG  1 
ATOM   8484  C CD  . PRO C 1 198 ? 157.947 166.632 187.251 1.00 23.05  ? 219 PRO C CD  1 
ATOM   8485  N N   . VAL C 1 199 ? 159.575 166.408 191.470 1.00 21.63  ? 220 VAL C N   1 
ATOM   8486  C CA  . VAL C 1 199 ? 160.578 167.038 192.321 1.00 21.63  ? 220 VAL C CA  1 
ATOM   8487  C C   . VAL C 1 199 ? 161.782 166.110 192.395 1.00 21.63  ? 220 VAL C C   1 
ATOM   8488  O O   . VAL C 1 199 ? 161.650 164.945 192.790 1.00 21.63  ? 220 VAL C O   1 
ATOM   8489  C CB  . VAL C 1 199 ? 160.024 167.335 193.724 1.00 21.63  ? 220 VAL C CB  1 
ATOM   8490  C CG1 . VAL C 1 199 ? 161.143 167.700 194.685 1.00 21.63  ? 220 VAL C CG1 1 
ATOM   8491  C CG2 . VAL C 1 199 ? 159.006 168.446 193.659 1.00 21.63  ? 220 VAL C CG2 1 
ATOM   8492  N N   . SER C 1 200 ? 162.948 166.621 192.008 1.00 20.75  ? 221 SER C N   1 
ATOM   8493  C CA  . SER C 1 200 ? 164.180 165.860 192.149 1.00 20.75  ? 221 SER C CA  1 
ATOM   8494  C C   . SER C 1 200 ? 164.591 165.785 193.615 1.00 20.75  ? 221 SER C C   1 
ATOM   8495  O O   . SER C 1 200 ? 164.320 166.692 194.406 1.00 20.75  ? 221 SER C O   1 
ATOM   8496  C CB  . SER C 1 200 ? 165.297 166.492 191.321 1.00 20.75  ? 221 SER C CB  1 
ATOM   8497  O OG  . SER C 1 200 ? 164.988 166.456 189.939 1.00 20.75  ? 221 SER C OG  1 
ATOM   8498  N N   . ILE C 1 201 ? 165.259 164.685 193.975 1.00 19.63  ? 222 ILE C N   1 
ATOM   8499  C CA  . ILE C 1 201 ? 165.605 164.458 195.373 1.00 19.63  ? 222 ILE C CA  1 
ATOM   8500  C C   . ILE C 1 201 ? 166.763 165.350 195.822 1.00 19.63  ? 222 ILE C C   1 
ATOM   8501  O O   . ILE C 1 201 ? 166.923 165.586 197.024 1.00 19.63  ? 222 ILE C O   1 
ATOM   8502  C CB  . ILE C 1 201 ? 165.892 162.957 195.599 1.00 19.63  ? 222 ILE C CB  1 
ATOM   8503  C CG1 . ILE C 1 201 ? 165.719 162.571 197.072 1.00 19.63  ? 222 ILE C CG1 1 
ATOM   8504  C CG2 . ILE C 1 201 ? 167.272 162.573 195.102 1.00 19.63  ? 222 ILE C CG2 1 
ATOM   8505  C CD1 . ILE C 1 201 ? 164.287 162.604 197.546 1.00 19.63  ? 222 ILE C CD1 1 
ATOM   8506  N N   . GLN C 1 202 ? 167.552 165.894 194.890 1.00 21.00  ? 223 GLN C N   1 
ATOM   8507  C CA  . GLN C 1 202 ? 168.604 166.831 195.275 1.00 21.00  ? 223 GLN C CA  1 
ATOM   8508  C C   . GLN C 1 202 ? 168.017 168.182 195.671 1.00 21.00  ? 223 GLN C C   1 
ATOM   8509  O O   . GLN C 1 202 ? 168.419 168.771 196.684 1.00 21.00  ? 223 GLN C O   1 
ATOM   8510  C CB  . GLN C 1 202 ? 169.607 166.988 194.132 1.00 21.00  ? 223 GLN C CB  1 
ATOM   8511  C CG  . GLN C 1 202 ? 170.728 167.974 194.412 1.00 21.00  ? 223 GLN C CG  1 
ATOM   8512  C CD  . GLN C 1 202 ? 171.486 167.647 195.683 1.00 21.00  ? 223 GLN C CD  1 
ATOM   8513  O OE1 . GLN C 1 202 ? 171.375 168.354 196.684 1.00 21.00  ? 223 GLN C OE1 1 
ATOM   8514  N NE2 . GLN C 1 202 ? 172.260 166.569 195.649 1.00 21.00  ? 223 GLN C NE2 1 
ATOM   8515  N N   . ALA C 1 203 ? 167.046 168.671 194.894 1.00 20.94  ? 224 ALA C N   1 
ATOM   8516  C CA  . ALA C 1 203 ? 166.369 169.920 195.228 1.00 20.94  ? 224 ALA C CA  1 
ATOM   8517  C C   . ALA C 1 203 ? 165.551 169.781 196.506 1.00 20.94  ? 224 ALA C C   1 
ATOM   8518  O O   . ALA C 1 203 ? 165.468 170.724 197.300 1.00 20.94  ? 224 ALA C O   1 
ATOM   8519  C CB  . ALA C 1 203 ? 165.480 170.362 194.067 1.00 20.94  ? 224 ALA C CB  1 
ATOM   8520  N N   . LEU C 1 204 ? 164.951 168.608 196.724 1.00 17.58  ? 225 LEU C N   1 
ATOM   8521  C CA  . LEU C 1 204 ? 164.235 168.362 197.970 1.00 17.58  ? 225 LEU C CA  1 
ATOM   8522  C C   . LEU C 1 204 ? 165.200 168.250 199.148 1.00 17.58  ? 225 LEU C C   1 
ATOM   8523  O O   . LEU C 1 204 ? 164.891 168.705 200.256 1.00 17.58  ? 225 LEU C O   1 
ATOM   8524  C CB  . LEU C 1 204 ? 163.381 167.101 197.834 1.00 17.58  ? 225 LEU C CB  1 
ATOM   8525  C CG  . LEU C 1 204 ? 162.628 166.612 199.069 1.00 17.58  ? 225 LEU C CG  1 
ATOM   8526  C CD1 . LEU C 1 204 ? 161.670 167.688 199.532 1.00 17.58  ? 225 LEU C CD1 1 
ATOM   8527  C CD2 . LEU C 1 204 ? 161.882 165.325 198.766 1.00 17.58  ? 225 LEU C CD2 1 
ATOM   8528  N N   . SER C 1 205 ? 166.389 167.685 198.920 1.00 16.81  ? 226 SER C N   1 
ATOM   8529  C CA  . SER C 1 205 ? 167.389 167.585 199.977 1.00 16.81  ? 226 SER C CA  1 
ATOM   8530  C C   . SER C 1 205 ? 168.071 168.916 200.259 1.00 16.81  ? 226 SER C C   1 
ATOM   8531  O O   . SER C 1 205 ? 168.754 169.041 201.281 1.00 16.81  ? 226 SER C O   1 
ATOM   8532  C CB  . SER C 1 205 ? 168.439 166.537 199.613 1.00 16.81  ? 226 SER C CB  1 
ATOM   8533  O OG  . SER C 1 205 ? 169.270 166.998 198.564 1.00 16.81  ? 226 SER C OG  1 
ATOM   8534  N N   . GLN C 1 206 ? 167.917 169.902 199.368 1.00 17.19  ? 227 GLN C N   1 
ATOM   8535  C CA  . GLN C 1 206 ? 168.412 171.251 199.638 1.00 17.19  ? 227 GLN C CA  1 
ATOM   8536  C C   . GLN C 1 206 ? 167.714 171.924 200.820 1.00 17.19  ? 227 GLN C C   1 
ATOM   8537  O O   . GLN C 1 206 ? 168.263 172.878 201.380 1.00 17.19  ? 227 GLN C O   1 
ATOM   8538  C CB  . GLN C 1 206 ? 168.258 172.134 198.399 1.00 17.19  ? 227 GLN C CB  1 
ATOM   8539  C CG  . GLN C 1 206 ? 169.324 171.927 197.341 1.00 17.19  ? 227 GLN C CG  1 
ATOM   8540  C CD  . GLN C 1 206 ? 170.685 172.420 197.788 1.00 17.19  ? 227 GLN C CD  1 
ATOM   8541  O OE1 . GLN C 1 206 ? 170.795 173.439 198.469 1.00 17.19  ? 227 GLN C OE1 1 
ATOM   8542  N NE2 . GLN C 1 206 ? 171.732 171.699 197.403 1.00 17.19  ? 227 GLN C NE2 1 
ATOM   8543  N N   . LEU C 1 207 ? 166.518 171.464 201.203 1.00 15.29  ? 228 LEU C N   1 
ATOM   8544  C CA  . LEU C 1 207 ? 165.847 172.006 202.382 1.00 15.29  ? 228 LEU C CA  1 
ATOM   8545  C C   . LEU C 1 207 ? 166.553 171.611 203.673 1.00 15.29  ? 228 LEU C C   1 
ATOM   8546  O O   . LEU C 1 207 ? 166.492 172.350 204.662 1.00 15.29  ? 228 LEU C O   1 
ATOM   8547  C CB  . LEU C 1 207 ? 164.394 171.535 202.426 1.00 15.29  ? 228 LEU C CB  1 
ATOM   8548  C CG  . LEU C 1 207 ? 163.396 172.164 201.455 1.00 15.29  ? 228 LEU C CG  1 
ATOM   8549  C CD1 . LEU C 1 207 ? 161.989 171.683 201.767 1.00 15.29  ? 228 LEU C CD1 1 
ATOM   8550  C CD2 . LEU C 1 207 ? 163.470 173.677 201.530 1.00 15.29  ? 228 LEU C CD2 1 
ATOM   8551  N N   . PHE C 1 208 ? 167.222 170.460 203.685 1.00 20.25  ? 229 PHE C N   1 
ATOM   8552  C CA  . PHE C 1 208 ? 167.822 169.886 204.888 1.00 20.25  ? 229 PHE C CA  1 
ATOM   8553  C C   . PHE C 1 208 ? 169.332 170.070 204.920 1.00 20.25  ? 229 PHE C C   1 
ATOM   8554  O O   . PHE C 1 208 ? 170.059 169.160 205.333 1.00 20.25  ? 229 PHE C O   1 
ATOM   8555  C CB  . PHE C 1 208 ? 167.452 168.411 204.994 1.00 20.25  ? 229 PHE C CB  1 
ATOM   8556  C CG  . PHE C 1 208 ? 166.025 168.130 204.639 1.00 20.25  ? 229 PHE C CG  1 
ATOM   8557  C CD1 . PHE C 1 208 ? 165.004 168.518 205.488 1.00 20.25  ? 229 PHE C CD1 1 
ATOM   8558  C CD2 . PHE C 1 208 ? 165.698 167.514 203.441 1.00 20.25  ? 229 PHE C CD2 1 
ATOM   8559  C CE1 . PHE C 1 208 ? 163.684 168.277 205.167 1.00 20.25  ? 229 PHE C CE1 1 
ATOM   8560  C CE2 . PHE C 1 208 ? 164.377 167.274 203.111 1.00 20.25  ? 229 PHE C CE2 1 
ATOM   8561  C CZ  . PHE C 1 208 ? 163.371 167.657 203.974 1.00 20.25  ? 229 PHE C CZ  1 
ATOM   8562  N N   . GLU C 1 209 ? 169.799 171.244 204.470 1.00 27.44  ? 230 GLU C N   1 
ATOM   8563  C CA  . GLU C 1 209 ? 171.216 171.627 204.389 1.00 27.44  ? 230 GLU C CA  1 
ATOM   8564  C C   . GLU C 1 209 ? 172.030 170.662 203.529 1.00 27.44  ? 230 GLU C C   1 
ATOM   8565  O O   . GLU C 1 209 ? 173.190 170.373 203.832 1.00 27.44  ? 230 GLU C O   1 
ATOM   8566  C CB  . GLU C 1 209 ? 171.852 171.774 205.778 1.00 27.44  ? 230 GLU C CB  1 
ATOM   8567  C CG  . GLU C 1 209 ? 171.062 172.640 206.748 1.00 27.44  ? 230 GLU C CG  1 
ATOM   8568  C CD  . GLU C 1 209 ? 170.747 174.013 206.188 1.00 27.44  ? 230 GLU C CD  1 
ATOM   8569  O OE1 . GLU C 1 209 ? 171.683 174.699 205.728 1.00 27.44  ? 230 GLU C OE1 1 
ATOM   8570  O OE2 . GLU C 1 209 ? 169.562 174.409 206.217 1.00 27.44  ? 230 GLU C OE2 1 
ATOM   8571  N N   . GLY C 1 210 ? 171.431 170.174 202.443 1.00 22.58  ? 231 GLY C N   1 
ATOM   8572  C CA  . GLY C 1 210 ? 172.106 169.270 201.532 1.00 22.58  ? 231 GLY C CA  1 
ATOM   8573  C C   . GLY C 1 210 ? 172.398 167.900 202.108 1.00 22.58  ? 231 GLY C C   1 
ATOM   8574  O O   . GLY C 1 210 ? 173.535 167.425 202.040 1.00 22.58  ? 231 GLY C O   1 
ATOM   8575  N N   . ASN C 1 211 ? 171.385 167.254 202.679 1.00 18.33  ? 232 ASN C N   1 
ATOM   8576  C CA  . ASN C 1 211 ? 171.536 165.946 203.312 1.00 18.33  ? 232 ASN C CA  1 
ATOM   8577  C C   . ASN C 1 211 ? 170.670 164.948 202.548 1.00 18.33  ? 232 ASN C C   1 
ATOM   8578  O O   . ASN C 1 211 ? 169.516 164.705 202.907 1.00 18.33  ? 232 ASN C O   1 
ATOM   8579  C CB  . ASN C 1 211 ? 171.152 166.011 204.787 1.00 18.33  ? 232 ASN C CB  1 
ATOM   8580  C CG  . ASN C 1 211 ? 171.778 164.899 205.601 1.00 18.33  ? 232 ASN C CG  1 
ATOM   8581  O OD1 . ASN C 1 211 ? 172.371 163.972 205.053 1.00 18.33  ? 232 ASN C OD1 1 
ATOM   8582  N ND2 . ASN C 1 211 ? 171.650 164.988 206.919 1.00 18.33  ? 232 ASN C ND2 1 
ATOM   8583  N N   . LEU C 1 212 ? 171.237 164.367 201.490 1.00 17.74  ? 233 LEU C N   1 
ATOM   8584  C CA  . LEU C 1 212 ? 170.509 163.393 200.685 1.00 17.74  ? 233 LEU C CA  1 
ATOM   8585  C C   . LEU C 1 212 ? 170.488 162.015 201.335 1.00 17.74  ? 233 LEU C C   1 
ATOM   8586  O O   . LEU C 1 212 ? 169.517 161.266 201.160 1.00 17.74  ? 233 LEU C O   1 
ATOM   8587  C CB  . LEU C 1 212 ? 171.125 163.319 199.284 1.00 17.74  ? 233 LEU C CB  1 
ATOM   8588  C CG  . LEU C 1 212 ? 170.371 162.633 198.141 1.00 17.74  ? 233 LEU C CG  1 
ATOM   8589  C CD1 . LEU C 1 212 ? 170.607 163.400 196.856 1.00 17.74  ? 233 LEU C CD1 1 
ATOM   8590  C CD2 . LEU C 1 212 ? 170.806 161.185 197.957 1.00 17.74  ? 233 LEU C CD2 1 
ATOM   8591  N N   . GLU C 1 213 ? 171.545 161.666 202.075 1.00 19.39  ? 234 GLU C N   1 
ATOM   8592  C CA  . GLU C 1 213 ? 171.632 160.337 202.670 1.00 19.39  ? 234 GLU C CA  1 
ATOM   8593  C C   . GLU C 1 213 ? 170.639 160.159 203.809 1.00 19.39  ? 234 GLU C C   1 
ATOM   8594  O O   . GLU C 1 213 ? 170.213 159.031 204.075 1.00 19.39  ? 234 GLU C O   1 
ATOM   8595  C CB  . GLU C 1 213 ? 173.055 160.067 203.156 1.00 19.39  ? 234 GLU C CB  1 
ATOM   8596  C CG  . GLU C 1 213 ? 173.440 158.593 203.176 1.00 19.39  ? 234 GLU C CG  1 
ATOM   8597  C CD  . GLU C 1 213 ? 173.482 157.965 201.794 1.00 19.39  ? 234 GLU C CD  1 
ATOM   8598  O OE1 . GLU C 1 213 ? 173.836 158.666 200.823 1.00 19.39  ? 234 GLU C OE1 1 
ATOM   8599  O OE2 . GLU C 1 213 ? 173.163 156.762 201.680 1.00 19.39  ? 234 GLU C OE2 1 
ATOM   8600  N N   . LEU C 1 214 ? 170.246 161.253 204.472 1.00 18.80  ? 235 LEU C N   1 
ATOM   8601  C CA  . LEU C 1 214 ? 169.199 161.181 205.487 1.00 18.80  ? 235 LEU C CA  1 
ATOM   8602  C C   . LEU C 1 214 ? 167.859 160.785 204.878 1.00 18.80  ? 235 LEU C C   1 
ATOM   8603  O O   . LEU C 1 214 ? 167.166 159.910 205.412 1.00 18.80  ? 235 LEU C O   1 
ATOM   8604  C CB  . LEU C 1 214 ? 169.078 162.520 206.213 1.00 18.80  ? 235 LEU C CB  1 
ATOM   8605  C CG  . LEU C 1 214 ? 168.035 162.596 207.329 1.00 18.80  ? 235 LEU C CG  1 
ATOM   8606  C CD1 . LEU C 1 214 ? 168.267 161.508 208.364 1.00 18.80  ? 235 LEU C CD1 1 
ATOM   8607  C CD2 . LEU C 1 214 ? 168.047 163.969 207.978 1.00 18.80  ? 235 LEU C CD2 1 
ATOM   8608  N N   . LEU C 1 215 ? 167.494 161.395 203.747 1.00 14.95  ? 236 LEU C N   1 
ATOM   8609  C CA  . LEU C 1 215 ? 166.255 161.031 203.066 1.00 14.95  ? 236 LEU C CA  1 
ATOM   8610  C C   . LEU C 1 215 ? 166.333 159.641 202.452 1.00 14.95  ? 236 LEU C C   1 
ATOM   8611  O O   . LEU C 1 215 ? 165.328 158.921 202.435 1.00 14.95  ? 236 LEU C O   1 
ATOM   8612  C CB  . LEU C 1 215 ? 165.923 162.060 201.989 1.00 14.95  ? 236 LEU C CB  1 
ATOM   8613  C CG  . LEU C 1 215 ? 165.961 163.514 202.442 1.00 14.95  ? 236 LEU C CG  1 
ATOM   8614  C CD1 . LEU C 1 215 ? 165.692 164.433 201.266 1.00 14.95  ? 236 LEU C CD1 1 
ATOM   8615  C CD2 . LEU C 1 215 ? 164.951 163.733 203.552 1.00 14.95  ? 236 LEU C CD2 1 
ATOM   8616  N N   . THR C 1 216 ? 167.507 159.256 201.942 1.00 19.24  ? 237 THR C N   1 
ATOM   8617  C CA  . THR C 1 216 ? 167.680 157.919 201.378 1.00 19.24  ? 237 THR C CA  1 
ATOM   8618  C C   . THR C 1 216 ? 167.562 156.842 202.457 1.00 19.24  ? 237 THR C C   1 
ATOM   8619  O O   . THR C 1 216 ? 166.905 155.815 202.248 1.00 19.24  ? 237 THR C O   1 
ATOM   8620  C CB  . THR C 1 216 ? 169.028 157.849 200.653 1.00 19.24  ? 237 THR C CB  1 
ATOM   8621  O OG1 . THR C 1 216 ? 168.975 158.672 199.481 1.00 19.24  ? 237 THR C OG1 1 
ATOM   8622  C CG2 . THR C 1 216 ? 169.370 156.429 200.227 1.00 19.24  ? 237 THR C CG2 1 
ATOM   8623  N N   . SER C 1 217 ? 168.142 157.084 203.637 1.00 22.19  ? 238 SER C N   1 
ATOM   8624  C CA  . SER C 1 217 ? 168.053 156.117 204.725 1.00 22.19  ? 238 SER C CA  1 
ATOM   8625  C C   . SER C 1 217 ? 166.665 156.087 205.355 1.00 22.19  ? 238 SER C C   1 
ATOM   8626  O O   . SER C 1 217 ? 166.174 155.009 205.707 1.00 22.19  ? 238 SER C O   1 
ATOM   8627  C CB  . SER C 1 217 ? 169.108 156.426 205.786 1.00 22.19  ? 238 SER C CB  1 
ATOM   8628  O OG  . SER C 1 217 ? 169.012 155.528 206.877 1.00 22.19  ? 238 SER C OG  1 
ATOM   8629  N N   . SER C 1 218 ? 166.013 157.245 205.503 1.00 21.51  ? 239 SER C N   1 
ATOM   8630  C CA  . SER C 1 218 ? 164.679 157.274 206.086 1.00 21.51  ? 239 SER C CA  1 
ATOM   8631  C C   . SER C 1 218 ? 163.601 156.843 205.104 1.00 21.51  ? 239 SER C C   1 
ATOM   8632  O O   . SER C 1 218 ? 162.476 156.556 205.527 1.00 21.51  ? 239 SER C O   1 
ATOM   8633  C CB  . SER C 1 218 ? 164.359 158.675 206.610 1.00 21.51  ? 239 SER C CB  1 
ATOM   8634  O OG  . SER C 1 218 ? 165.269 159.059 207.626 1.00 21.51  ? 239 SER C OG  1 
ATOM   8635  N N   . LEU C 1 219 ? 163.913 156.794 203.811 1.00 22.54  ? 240 LEU C N   1 
ATOM   8636  C CA  . LEU C 1 219 ? 162.943 156.367 202.816 1.00 22.54  ? 240 LEU C CA  1 
ATOM   8637  C C   . LEU C 1 219 ? 162.875 154.854 202.665 1.00 22.54  ? 240 LEU C C   1 
ATOM   8638  O O   . LEU C 1 219 ? 161.780 154.313 202.481 1.00 22.54  ? 240 LEU C O   1 
ATOM   8639  C CB  . LEU C 1 219 ? 163.265 157.024 201.470 1.00 22.54  ? 240 LEU C CB  1 
ATOM   8640  C CG  . LEU C 1 219 ? 162.293 156.789 200.319 1.00 22.54  ? 240 LEU C CG  1 
ATOM   8641  C CD1 . LEU C 1 219 ? 160.923 157.252 200.741 1.00 22.54  ? 240 LEU C CD1 1 
ATOM   8642  C CD2 . LEU C 1 219 ? 162.751 157.557 199.096 1.00 22.54  ? 240 LEU C CD2 1 
ATOM   8643  N N   . GLY C 1 220 ? 164.002 154.154 202.768 1.00 30.35  ? 241 GLY C N   1 
ATOM   8644  C CA  . GLY C 1 220 ? 164.037 152.704 202.713 1.00 30.35  ? 241 GLY C CA  1 
ATOM   8645  C C   . GLY C 1 220 ? 165.050 152.125 201.749 1.00 30.35  ? 241 GLY C C   1 
ATOM   8646  O O   . GLY C 1 220 ? 165.377 150.935 201.857 1.00 30.35  ? 241 GLY C O   1 
ATOM   8647  N N   . ILE C 1 221 ? 165.559 152.915 200.808 1.00 35.34  ? 242 ILE C N   1 
ATOM   8648  C CA  . ILE C 1 221 ? 166.561 152.431 199.862 1.00 35.34  ? 242 ILE C CA  1 
ATOM   8649  C C   . ILE C 1 221 ? 167.906 152.369 200.574 1.00 35.34  ? 242 ILE C C   1 
ATOM   8650  O O   . ILE C 1 221 ? 168.366 153.364 201.143 1.00 35.34  ? 242 ILE C O   1 
ATOM   8651  C CB  . ILE C 1 221 ? 166.639 153.320 198.608 1.00 35.34  ? 242 ILE C CB  1 
ATOM   8652  C CG1 . ILE C 1 221 ? 165.351 153.257 197.776 1.00 35.34  ? 242 ILE C CG1 1 
ATOM   8653  C CG2 . ILE C 1 221 ? 167.826 152.933 197.737 1.00 35.34  ? 242 ILE C CG2 1 
ATOM   8654  C CD1 . ILE C 1 221 ? 164.336 154.338 198.071 1.00 35.34  ? 242 ILE C CD1 1 
ATOM   8655  N N   . SER C 1 222 ? 168.535 151.196 200.550 1.00 60.97  ? 243 SER C N   1 
ATOM   8656  C CA  . SER C 1 222 ? 169.863 150.998 201.129 1.00 60.97  ? 243 SER C CA  1 
ATOM   8657  C C   . SER C 1 222 ? 170.749 150.370 200.057 1.00 60.97  ? 243 SER C C   1 
ATOM   8658  O O   . SER C 1 222 ? 170.687 149.158 199.825 1.00 60.97  ? 243 SER C O   1 
ATOM   8659  C CB  . SER C 1 222 ? 169.797 150.127 202.379 1.00 60.97  ? 243 SER C CB  1 
ATOM   8660  O OG  . SER C 1 222 ? 171.089 149.913 202.917 1.00 60.97  ? 243 SER C OG  1 
ATOM   8661  N N   . SER C 1 223 ? 171.558 151.196 199.400 1.00 84.61  ? 244 SER C N   1 
ATOM   8662  C CA  . SER C 1 223 ? 172.468 150.701 198.377 1.00 84.61  ? 244 SER C CA  1 
ATOM   8663  C C   . SER C 1 223 ? 173.615 149.926 199.012 1.00 84.61  ? 244 SER C C   1 
ATOM   8664  O O   . SER C 1 223 ? 174.144 150.312 200.058 1.00 84.61  ? 244 SER C O   1 
ATOM   8665  C CB  . SER C 1 223 ? 173.013 151.861 197.545 1.00 84.61  ? 244 SER C CB  1 
ATOM   8666  O OG  . SER C 1 223 ? 171.967 152.543 196.875 1.00 84.61  ? 244 SER C OG  1 
ATOM   8667  N N   . THR C 1 224 ? 174.002 148.823 198.371 1.00 92.00  ? 245 THR C N   1 
ATOM   8668  C CA  . THR C 1 224 ? 175.062 147.970 198.886 1.00 92.00  ? 245 THR C CA  1 
ATOM   8669  C C   . THR C 1 224 ? 176.132 147.617 197.863 1.00 92.00  ? 245 THR C C   1 
ATOM   8670  O O   . THR C 1 224 ? 177.173 147.079 198.256 1.00 92.00  ? 245 THR C O   1 
ATOM   8671  C CB  . THR C 1 224 ? 174.477 146.668 199.459 1.00 92.00  ? 245 THR C CB  1 
ATOM   8672  O OG1 . THR C 1 224 ? 175.514 145.913 200.097 1.00 92.00  ? 245 THR C OG1 1 
ATOM   8673  C CG2 . THR C 1 224 ? 173.846 145.830 198.357 1.00 92.00  ? 245 THR C CG2 1 
ATOM   8674  N N   . ASP C 1 225 ? 175.921 147.897 196.582 1.00 87.47  ? 246 ASP C N   1 
ATOM   8675  C CA  . ASP C 1 225 ? 176.907 147.634 195.545 1.00 87.47  ? 246 ASP C CA  1 
ATOM   8676  C C   . ASP C 1 225 ? 177.469 148.945 195.008 1.00 87.47  ? 246 ASP C C   1 
ATOM   8677  O O   . ASP C 1 225 ? 177.006 150.036 195.349 1.00 87.47  ? 246 ASP C O   1 
ATOM   8678  C CB  . ASP C 1 225 ? 176.302 146.791 194.415 1.00 87.47  ? 246 ASP C CB  1 
ATOM   8679  C CG  . ASP C 1 225 ? 174.990 147.350 193.902 1.00 87.47  ? 246 ASP C CG  1 
ATOM   8680  O OD1 . ASP C 1 225 ? 174.459 148.296 194.518 1.00 87.47  ? 246 ASP C OD1 1 
ATOM   8681  O OD2 . ASP C 1 225 ? 174.486 146.841 192.879 1.00 87.47  ? 246 ASP C OD2 1 
ATOM   8682  N N   . PHE C 1 226 ? 178.484 148.818 194.151 1.00 64.42  ? 247 PHE C N   1 
ATOM   8683  C CA  . PHE C 1 226 ? 179.224 149.987 193.687 1.00 64.42  ? 247 PHE C CA  1 
ATOM   8684  C C   . PHE C 1 226 ? 178.433 150.804 192.672 1.00 64.42  ? 247 PHE C C   1 
ATOM   8685  O O   . PHE C 1 226 ? 178.684 152.004 192.516 1.00 64.42  ? 247 PHE C O   1 
ATOM   8686  C CB  . PHE C 1 226 ? 180.559 149.548 193.088 1.00 64.42  ? 247 PHE C CB  1 
ATOM   8687  C CG  . PHE C 1 226 ? 181.615 150.612 193.110 1.00 64.42  ? 247 PHE C CG  1 
ATOM   8688  C CD1 . PHE C 1 226 ? 181.868 151.332 194.267 1.00 64.42  ? 247 PHE C CD1 1 
ATOM   8689  C CD2 . PHE C 1 226 ? 182.365 150.884 191.974 1.00 64.42  ? 247 PHE C CD2 1 
ATOM   8690  C CE1 . PHE C 1 226 ? 182.845 152.312 194.291 1.00 64.42  ? 247 PHE C CE1 1 
ATOM   8691  C CE2 . PHE C 1 226 ? 183.344 151.861 191.990 1.00 64.42  ? 247 PHE C CE2 1 
ATOM   8692  C CZ  . PHE C 1 226 ? 183.584 152.575 193.151 1.00 64.42  ? 247 PHE C CZ  1 
ATOM   8693  N N   . ASN C 1 227 ? 177.483 150.180 191.974 1.00 71.27  ? 248 ASN C N   1 
ATOM   8694  C CA  . ASN C 1 227 ? 176.723 150.889 190.951 1.00 71.27  ? 248 ASN C CA  1 
ATOM   8695  C C   . ASN C 1 227 ? 175.655 151.800 191.545 1.00 71.27  ? 248 ASN C C   1 
ATOM   8696  O O   . ASN C 1 227 ? 175.387 152.872 190.992 1.00 71.27  ? 248 ASN C O   1 
ATOM   8697  C CB  . ASN C 1 227 ? 176.084 149.886 189.988 1.00 71.27  ? 248 ASN C CB  1 
ATOM   8698  C CG  . ASN C 1 227 ? 175.586 150.536 188.710 1.00 71.27  ? 248 ASN C CG  1 
ATOM   8699  O OD1 . ASN C 1 227 ? 174.536 151.179 188.693 1.00 71.27  ? 248 ASN C OD1 1 
ATOM   8700  N ND2 . ASN C 1 227 ? 176.341 150.370 187.631 1.00 71.27  ? 248 ASN C ND2 1 
ATOM   8701  N N   . ASP C 1 228 ? 175.041 151.401 192.655 1.00 78.53  ? 249 ASP C N   1 
ATOM   8702  C CA  . ASP C 1 228 ? 173.912 152.128 193.222 1.00 78.53  ? 249 ASP C CA  1 
ATOM   8703  C C   . ASP C 1 228 ? 174.329 153.200 194.223 1.00 78.53  ? 249 ASP C C   1 
ATOM   8704  O O   . ASP C 1 228 ? 173.462 153.916 194.735 1.00 78.53  ? 249 ASP C O   1 
ATOM   8705  C CB  . ASP C 1 228 ? 172.943 151.144 193.887 1.00 78.53  ? 249 ASP C CB  1 
ATOM   8706  C CG  . ASP C 1 228 ? 171.502 151.615 193.845 1.00 78.53  ? 249 ASP C CG  1 
ATOM   8707  O OD1 . ASP C 1 228 ? 171.232 152.668 193.234 1.00 78.53  ? 249 ASP C OD1 1 
ATOM   8708  O OD2 . ASP C 1 228 ? 170.637 150.925 194.424 1.00 78.53  ? 249 ASP C OD2 1 
ATOM   8709  N N   . LEU C 1 229 ? 175.624 153.323 194.528 1.00 66.20  ? 250 LEU C N   1 
ATOM   8710  C CA  . LEU C 1 229 ? 176.072 154.388 195.421 1.00 66.20  ? 250 LEU C CA  1 
ATOM   8711  C C   . LEU C 1 229 ? 176.022 155.744 194.730 1.00 66.20  ? 250 LEU C C   1 
ATOM   8712  O O   . LEU C 1 229 ? 175.546 156.729 195.307 1.00 66.20  ? 250 LEU C O   1 
ATOM   8713  C CB  . LEU C 1 229 ? 177.484 154.096 195.928 1.00 66.20  ? 250 LEU C CB  1 
ATOM   8714  C CG  . LEU C 1 229 ? 177.630 152.940 196.916 1.00 66.20  ? 250 LEU C CG  1 
ATOM   8715  C CD1 . LEU C 1 229 ? 179.081 152.498 197.007 1.00 66.20  ? 250 LEU C CD1 1 
ATOM   8716  C CD2 . LEU C 1 229 ? 177.100 153.337 198.283 1.00 66.20  ? 250 LEU C CD2 1 
ATOM   8717  N N   . LEU C 1 230 ? 176.515 155.816 193.490 1.00 54.68  ? 251 LEU C N   1 
ATOM   8718  C CA  . LEU C 1 230 ? 176.453 157.069 192.744 1.00 54.68  ? 251 LEU C CA  1 
ATOM   8719  C C   . LEU C 1 230 ? 175.038 157.367 192.270 1.00 54.68  ? 251 LEU C C   1 
ATOM   8720  O O   . LEU C 1 230 ? 174.679 158.536 192.090 1.00 54.68  ? 251 LEU C O   1 
ATOM   8721  C CB  . LEU C 1 230 ? 177.416 157.027 191.558 1.00 54.68  ? 251 LEU C CB  1 
ATOM   8722  C CG  . LEU C 1 230 ? 178.896 157.223 191.895 1.00 54.68  ? 251 LEU C CG  1 
ATOM   8723  C CD1 . LEU C 1 230 ? 179.780 156.659 190.795 1.00 54.68  ? 251 LEU C CD1 1 
ATOM   8724  C CD2 . LEU C 1 230 ? 179.198 158.694 192.131 1.00 54.68  ? 251 LEU C CD2 1 
ATOM   8725  N N   . THR C 1 231 ? 174.235 156.330 192.050 1.00 59.05  ? 252 THR C N   1 
ATOM   8726  C CA  . THR C 1 231 ? 172.822 156.516 191.758 1.00 59.05  ? 252 THR C CA  1 
ATOM   8727  C C   . THR C 1 231 ? 172.108 157.023 193.007 1.00 59.05  ? 252 THR C C   1 
ATOM   8728  O O   . THR C 1 231 ? 172.398 156.589 194.124 1.00 59.05  ? 252 THR C O   1 
ATOM   8729  C CB  . THR C 1 231 ? 172.211 155.196 191.279 1.00 59.05  ? 252 THR C CB  1 
ATOM   8730  O OG1 . THR C 1 231 ? 173.044 154.632 190.259 1.00 59.05  ? 252 THR C OG1 1 
ATOM   8731  C CG2 . THR C 1 231 ? 170.815 155.403 190.700 1.00 59.05  ? 252 THR C CG2 1 
ATOM   8732  N N   . GLY C 1 232 ? 171.175 157.950 192.817 1.00 40.77  ? 253 GLY C N   1 
ATOM   8733  C CA  . GLY C 1 232 ? 170.516 158.583 193.940 1.00 40.77  ? 253 GLY C CA  1 
ATOM   8734  C C   . GLY C 1 232 ? 170.384 160.078 193.753 1.00 40.77  ? 253 GLY C C   1 
ATOM   8735  O O   . GLY C 1 232 ? 170.042 160.804 194.689 1.00 40.77  ? 253 GLY C O   1 
ATOM   8736  N N   . LYS C 1 233 ? 170.681 160.548 192.544 1.00 32.72  ? 254 LYS C N   1 
ATOM   8737  C CA  . LYS C 1 233 ? 170.368 161.907 192.128 1.00 32.72  ? 254 LYS C CA  1 
ATOM   8738  C C   . LYS C 1 233 ? 169.214 161.941 191.135 1.00 32.72  ? 254 LYS C C   1 
ATOM   8739  O O   . LYS C 1 233 ? 168.975 162.977 190.506 1.00 32.72  ? 254 LYS C O   1 
ATOM   8740  C CB  . LYS C 1 233 ? 171.602 162.579 191.523 1.00 32.72  ? 254 LYS C CB  1 
ATOM   8741  C CG  . LYS C 1 233 ? 172.144 161.882 190.284 1.00 32.72  ? 254 LYS C CG  1 
ATOM   8742  C CD  . LYS C 1 233 ? 173.076 162.791 189.498 1.00 32.72  ? 254 LYS C CD  1 
ATOM   8743  C CE  . LYS C 1 233 ? 174.374 163.038 190.246 1.00 32.72  ? 254 LYS C CE  1 
ATOM   8744  N NZ  . LYS C 1 233 ? 175.169 161.790 190.406 1.00 32.72  ? 254 LYS C NZ  1 
ATOM   8745  N N   . LEU C 1 234 ? 168.492 160.828 190.984 1.00 32.59  ? 255 LEU C N   1 
ATOM   8746  C CA  . LEU C 1 234 ? 167.452 160.697 189.970 1.00 32.59  ? 255 LEU C CA  1 
ATOM   8747  C C   . LEU C 1 234 ? 166.172 160.076 190.524 1.00 32.59  ? 255 LEU C C   1 
ATOM   8748  O O   . LEU C 1 234 ? 165.337 159.597 189.751 1.00 32.59  ? 255 LEU C O   1 
ATOM   8749  C CB  . LEU C 1 234 ? 167.994 159.903 188.772 1.00 32.59  ? 255 LEU C CB  1 
ATOM   8750  C CG  . LEU C 1 234 ? 168.631 158.513 188.940 1.00 32.59  ? 255 LEU C CG  1 
ATOM   8751  C CD1 . LEU C 1 234 ? 167.646 157.348 188.915 1.00 32.59  ? 255 LEU C CD1 1 
ATOM   8752  C CD2 . LEU C 1 234 ? 169.721 158.309 187.893 1.00 32.59  ? 255 LEU C CD2 1 
ATOM   8753  N N   . ILE C 1 235 ? 165.992 160.088 191.841 1.00 22.63  ? 256 ILE C N   1 
ATOM   8754  C CA  . ILE C 1 235 ? 164.762 159.613 192.466 1.00 22.63  ? 256 ILE C CA  1 
ATOM   8755  C C   . ILE C 1 235 ? 163.762 160.763 192.449 1.00 22.63  ? 256 ILE C C   1 
ATOM   8756  O O   . ILE C 1 235 ? 163.929 161.754 193.162 1.00 22.63  ? 256 ILE C O   1 
ATOM   8757  C CB  . ILE C 1 235 ? 165.012 159.113 193.893 1.00 22.63  ? 256 ILE C CB  1 
ATOM   8758  C CG1 . ILE C 1 235 ? 166.112 158.047 193.899 1.00 22.63  ? 256 ILE C CG1 1 
ATOM   8759  C CG2 . ILE C 1 235 ? 163.724 158.581 194.500 1.00 22.63  ? 256 ILE C CG2 1 
ATOM   8760  C CD1 . ILE C 1 235 ? 166.327 157.382 195.244 1.00 22.63  ? 256 ILE C CD1 1 
ATOM   8761  N N   . THR C 1 236 ? 162.722 160.635 191.633 1.00 23.53  ? 257 THR C N   1 
ATOM   8762  C CA  . THR C 1 236 ? 161.739 161.695 191.476 1.00 23.53  ? 257 THR C CA  1 
ATOM   8763  C C   . THR C 1 236 ? 160.560 161.490 192.421 1.00 23.53  ? 257 THR C C   1 
ATOM   8764  O O   . THR C 1 236 ? 160.361 160.413 192.986 1.00 23.53  ? 257 THR C O   1 
ATOM   8765  C CB  . THR C 1 236 ? 161.242 161.760 190.032 1.00 23.53  ? 257 THR C CB  1 
ATOM   8766  O OG1 . THR C 1 236 ? 160.369 160.652 189.777 1.00 23.53  ? 257 THR C OG1 1 
ATOM   8767  C CG2 . THR C 1 236 ? 162.413 161.708 189.064 1.00 23.53  ? 257 THR C CG2 1 
ATOM   8768  N N   . GLY C 1 237 ? 159.772 162.550 192.584 1.00 23.81  ? 258 GLY C N   1 
ATOM   8769  C CA  . GLY C 1 237 ? 158.607 162.498 193.445 1.00 23.81  ? 258 GLY C CA  1 
ATOM   8770  C C   . GLY C 1 237 ? 157.657 163.628 193.134 1.00 23.81  ? 258 GLY C C   1 
ATOM   8771  O O   . GLY C 1 237 ? 158.070 164.700 192.680 1.00 23.81  ? 258 GLY C O   1 
ATOM   8772  N N   . SER C 1 238 ? 156.372 163.390 193.386 1.00 20.39  ? 259 SER C N   1 
ATOM   8773  C CA  . SER C 1 238 ? 155.322 164.354 193.100 1.00 20.39  ? 259 SER C CA  1 
ATOM   8774  C C   . SER C 1 238 ? 154.421 164.534 194.315 1.00 20.39  ? 259 SER C C   1 
ATOM   8775  O O   . SER C 1 238 ? 154.342 163.669 195.191 1.00 20.39  ? 259 SER C O   1 
ATOM   8776  C CB  . SER C 1 238 ? 154.486 163.920 191.890 1.00 20.39  ? 259 SER C CB  1 
ATOM   8777  O OG  . SER C 1 238 ? 153.990 162.604 192.061 1.00 20.39  ? 259 SER C OG  1 
ATOM   8778  N N   . ILE C 1 239 ? 153.740 165.676 194.356 1.00 11.94  ? 260 ILE C N   1 
ATOM   8779  C CA  . ILE C 1 239 ? 152.852 166.007 195.466 1.00 11.94  ? 260 ILE C CA  1 
ATOM   8780  C C   . ILE C 1 239 ? 151.507 165.330 195.245 1.00 11.94  ? 260 ILE C C   1 
ATOM   8781  O O   . ILE C 1 239 ? 150.968 165.346 194.132 1.00 11.94  ? 260 ILE C O   1 
ATOM   8782  C CB  . ILE C 1 239 ? 152.686 167.530 195.591 1.00 11.94  ? 260 ILE C CB  1 
ATOM   8783  C CG1 . ILE C 1 239 ? 154.039 168.231 195.486 1.00 11.94  ? 260 ILE C CG1 1 
ATOM   8784  C CG2 . ILE C 1 239 ? 152.005 167.893 196.902 1.00 11.94  ? 260 ILE C CG2 1 
ATOM   8785  C CD1 . ILE C 1 239 ? 153.953 169.737 195.577 1.00 11.94  ? 260 ILE C CD1 1 
ATOM   8786  N N   . ILE C 1 240 ? 150.961 164.726 196.299 1.00 19.84  ? 261 ILE C N   1 
ATOM   8787  C CA  . ILE C 1 240 ? 149.606 164.194 196.243 1.00 19.84  ? 261 ILE C CA  1 
ATOM   8788  C C   . ILE C 1 240 ? 148.648 164.896 197.196 1.00 19.84  ? 261 ILE C C   1 
ATOM   8789  O O   . ILE C 1 240 ? 147.427 164.807 196.988 1.00 19.84  ? 261 ILE C O   1 
ATOM   8790  C CB  . ILE C 1 240 ? 149.575 162.669 196.488 1.00 19.84  ? 261 ILE C CB  1 
ATOM   8791  C CG1 . ILE C 1 240 ? 150.017 162.327 197.909 1.00 19.84  ? 261 ILE C CG1 1 
ATOM   8792  C CG2 . ILE C 1 240 ? 150.433 161.940 195.468 1.00 19.84  ? 261 ILE C CG2 1 
ATOM   8793  C CD1 . ILE C 1 240 ? 149.763 160.893 198.294 1.00 19.84  ? 261 ILE C CD1 1 
ATOM   8794  N N   . TRP C 1 241 ? 149.127 165.596 198.226 1.00 23.48  ? 262 TRP C N   1 
ATOM   8795  C CA  . TRP C 1 241 ? 148.211 166.354 199.072 1.00 23.48  ? 262 TRP C CA  1 
ATOM   8796  C C   . TRP C 1 241 ? 148.919 167.578 199.634 1.00 23.48  ? 262 TRP C C   1 
ATOM   8797  O O   . TRP C 1 241 ? 150.127 167.559 199.873 1.00 23.48  ? 262 TRP C O   1 
ATOM   8798  C CB  . TRP C 1 241 ? 147.643 165.498 200.207 1.00 23.48  ? 262 TRP C CB  1 
ATOM   8799  C CG  . TRP C 1 241 ? 146.405 166.064 200.825 1.00 23.48  ? 262 TRP C CG  1 
ATOM   8800  C CD1 . TRP C 1 241 ? 146.283 166.577 202.079 1.00 23.48  ? 262 TRP C CD1 1 
ATOM   8801  C CD2 . TRP C 1 241 ? 145.111 166.167 200.221 1.00 23.48  ? 262 TRP C CD2 1 
ATOM   8802  N NE1 . TRP C 1 241 ? 144.994 166.997 202.297 1.00 23.48  ? 262 TRP C NE1 1 
ATOM   8803  C CE2 . TRP C 1 241 ? 144.254 166.757 201.171 1.00 23.48  ? 262 TRP C CE2 1 
ATOM   8804  C CE3 . TRP C 1 241 ? 144.593 165.820 198.969 1.00 23.48  ? 262 TRP C CE3 1 
ATOM   8805  C CZ2 . TRP C 1 241 ? 142.910 167.008 200.910 1.00 23.48  ? 262 TRP C CZ2 1 
ATOM   8806  C CZ3 . TRP C 1 241 ? 143.258 166.070 198.711 1.00 23.48  ? 262 TRP C CZ3 1 
ATOM   8807  C CH2 . TRP C 1 241 ? 142.432 166.658 199.677 1.00 23.48  ? 262 TRP C CH2 1 
ATOM   8808  N N   . ALA C 1 242 ? 148.141 168.633 199.870 1.00 14.19  ? 263 ALA C N   1 
ATOM   8809  C CA  . ALA C 1 242 ? 148.654 169.952 200.235 1.00 14.19  ? 263 ALA C CA  1 
ATOM   8810  C C   . ALA C 1 242 ? 147.849 170.542 201.390 1.00 14.19  ? 263 ALA C C   1 
ATOM   8811  O O   . ALA C 1 242 ? 147.282 171.629 201.277 1.00 14.19  ? 263 ALA C O   1 
ATOM   8812  C CB  . ALA C 1 242 ? 148.644 170.890 199.031 1.00 14.19  ? 263 ALA C CB  1 
ATOM   8813  N N   . ASP C 1 243 ? 147.758 169.801 202.499 1.00 34.58  ? 264 ASP C N   1 
ATOM   8814  C CA  . ASP C 1 243 ? 146.814 170.128 203.566 1.00 34.58  ? 264 ASP C CA  1 
ATOM   8815  C C   . ASP C 1 243 ? 147.186 171.423 204.282 1.00 34.58  ? 264 ASP C C   1 
ATOM   8816  O O   . ASP C 1 243 ? 148.347 171.638 204.652 1.00 34.58  ? 264 ASP C O   1 
ATOM   8817  C CB  . ASP C 1 243 ? 146.742 168.985 204.576 1.00 34.58  ? 264 ASP C CB  1 
ATOM   8818  C CG  . ASP C 1 243 ? 145.463 169.006 205.389 1.00 34.58  ? 264 ASP C CG  1 
ATOM   8819  O OD1 . ASP C 1 243 ? 144.581 169.840 205.094 1.00 34.58  ? 264 ASP C OD1 1 
ATOM   8820  O OD2 . ASP C 1 243 ? 145.335 168.187 206.322 1.00 34.58  ? 264 ASP C OD2 1 
ATOM   8821  N N   . THR C 1 244 ? 146.177 172.275 204.490 1.00 23.20  ? 265 THR C N   1 
ATOM   8822  C CA  . THR C 1 244 ? 146.356 173.636 204.974 1.00 23.20  ? 265 THR C CA  1 
ATOM   8823  C C   . THR C 1 244 ? 146.143 173.786 206.473 1.00 23.20  ? 265 THR C C   1 
ATOM   8824  O O   . THR C 1 244 ? 146.559 174.803 207.037 1.00 23.20  ? 265 THR C O   1 
ATOM   8825  C CB  . THR C 1 244 ? 145.392 174.585 204.252 1.00 23.20  ? 265 THR C CB  1 
ATOM   8826  O OG1 . THR C 1 244 ? 144.056 174.342 204.707 1.00 23.20  ? 265 THR C OG1 1 
ATOM   8827  C CG2 . THR C 1 244 ? 145.444 174.357 202.755 1.00 23.20  ? 265 THR C CG2 1 
ATOM   8828  N N   . GLN C 1 245 ? 145.495 172.821 207.128 1.00 30.60  ? 266 GLN C N   1 
ATOM   8829  C CA  . GLN C 1 245 ? 145.261 172.935 208.564 1.00 30.60  ? 266 GLN C CA  1 
ATOM   8830  C C   . GLN C 1 245 ? 146.543 172.701 209.351 1.00 30.60  ? 266 GLN C C   1 
ATOM   8831  O O   . GLN C 1 245 ? 146.949 173.545 210.158 1.00 30.60  ? 266 GLN C O   1 
ATOM   8832  C CB  . GLN C 1 245 ? 144.174 171.953 209.002 1.00 30.60  ? 266 GLN C CB  1 
ATOM   8833  C CG  . GLN C 1 245 ? 142.761 172.478 208.825 1.00 30.60  ? 266 GLN C CG  1 
ATOM   8834  C CD  . GLN C 1 245 ? 141.720 171.382 208.915 1.00 30.60  ? 266 GLN C CD  1 
ATOM   8835  O OE1 . GLN C 1 245 ? 141.722 170.584 209.851 1.00 30.60  ? 266 GLN C OE1 1 
ATOM   8836  N NE2 . GLN C 1 245 ? 140.822 171.339 207.938 1.00 30.60  ? 266 GLN C NE2 1 
ATOM   8837  N N   . GLY C 1 246 ? 147.195 171.566 209.126 1.00 27.62  ? 267 GLY C N   1 
ATOM   8838  C CA  . GLY C 1 246 ? 148.494 171.318 209.708 1.00 27.62  ? 267 GLY C CA  1 
ATOM   8839  C C   . GLY C 1 246 ? 149.656 171.898 208.941 1.00 27.62  ? 267 GLY C C   1 
ATOM   8840  O O   . GLY C 1 246 ? 150.795 171.777 209.404 1.00 27.62  ? 267 GLY C O   1 
ATOM   8841  N N   . HIS C 1 247 ? 149.376 172.524 207.790 1.00 23.64  ? 268 HIS C N   1 
ATOM   8842  C CA  . HIS C 1 247 ? 150.358 173.134 206.885 1.00 23.64  ? 268 HIS C CA  1 
ATOM   8843  C C   . HIS C 1 247 ? 151.423 172.124 206.449 1.00 23.64  ? 268 HIS C C   1 
ATOM   8844  O O   . HIS C 1 247 ? 152.625 172.337 206.615 1.00 23.64  ? 268 HIS C O   1 
ATOM   8845  C CB  . HIS C 1 247 ? 151.005 174.376 207.512 1.00 23.64  ? 268 HIS C CB  1 
ATOM   8846  C CG  . HIS C 1 247 ? 150.047 175.245 208.264 1.00 23.64  ? 268 HIS C CG  1 
ATOM   8847  N ND1 . HIS C 1 247 ? 149.296 176.227 207.655 1.00 23.64  ? 268 HIS C ND1 1 
ATOM   8848  C CD2 . HIS C 1 247 ? 149.719 175.279 209.577 1.00 23.64  ? 268 HIS C CD2 1 
ATOM   8849  C CE1 . HIS C 1 247 ? 148.547 176.829 208.561 1.00 23.64  ? 268 HIS C CE1 1 
ATOM   8850  N NE2 . HIS C 1 247 ? 148.784 176.273 209.735 1.00 23.64  ? 268 HIS C NE2 1 
ATOM   8851  N N   . TYR C 1 248 ? 150.963 171.010 205.887 1.00 22.88  ? 269 TYR C N   1 
ATOM   8852  C CA  . TYR C 1 248 ? 151.878 169.947 205.501 1.00 22.88  ? 269 TYR C CA  1 
ATOM   8853  C C   . TYR C 1 248 ? 151.572 169.466 204.090 1.00 22.88  ? 269 TYR C C   1 
ATOM   8854  O O   . TYR C 1 248 ? 150.493 169.704 203.540 1.00 22.88  ? 269 TYR C O   1 
ATOM   8855  C CB  . TYR C 1 248 ? 151.850 168.766 206.493 1.00 22.88  ? 269 TYR C CB  1 
ATOM   8856  C CG  . TYR C 1 248 ? 150.511 168.089 206.690 1.00 22.88  ? 269 TYR C CG  1 
ATOM   8857  C CD1 . TYR C 1 248 ? 149.614 168.549 207.646 1.00 22.88  ? 269 TYR C CD1 1 
ATOM   8858  C CD2 . TYR C 1 248 ? 150.161 166.967 205.947 1.00 22.88  ? 269 TYR C CD2 1 
ATOM   8859  C CE1 . TYR C 1 248 ? 148.395 167.927 207.840 1.00 22.88  ? 269 TYR C CE1 1 
ATOM   8860  C CE2 . TYR C 1 248 ? 148.944 166.339 206.132 1.00 22.88  ? 269 TYR C CE2 1 
ATOM   8861  C CZ  . TYR C 1 248 ? 148.068 166.822 207.081 1.00 22.88  ? 269 TYR C CZ  1 
ATOM   8862  O OH  . TYR C 1 248 ? 146.855 166.201 207.270 1.00 22.88  ? 269 TYR C OH  1 
ATOM   8863  N N   . LEU C 1 249 ? 152.567 168.808 203.500 1.00 49.69  ? 270 LEU C N   1 
ATOM   8864  C CA  . LEU C 1 249 ? 152.490 168.292 202.142 1.00 49.69  ? 270 LEU C CA  1 
ATOM   8865  C C   . LEU C 1 249 ? 152.719 166.790 202.187 1.00 49.69  ? 270 LEU C C   1 
ATOM   8866  O O   . LEU C 1 249 ? 153.763 166.332 202.664 1.00 49.69  ? 270 LEU C O   1 
ATOM   8867  C CB  . LEU C 1 249 ? 153.525 168.958 201.231 1.00 49.69  ? 270 LEU C CB  1 
ATOM   8868  C CG  . LEU C 1 249 ? 153.303 170.361 200.651 1.00 49.69  ? 270 LEU C CG  1 
ATOM   8869  C CD1 . LEU C 1 249 ? 153.461 171.470 201.684 1.00 49.69  ? 270 LEU C CD1 1 
ATOM   8870  C CD2 . LEU C 1 249 ? 154.243 170.591 199.478 1.00 49.69  ? 270 LEU C CD2 1 
ATOM   8871  N N   . ILE C 1 250 ? 151.755 166.030 201.686 1.00 17.17  ? 271 ILE C N   1 
ATOM   8872  C CA  . ILE C 1 250 ? 151.909 164.590 201.529 1.00 17.17  ? 271 ILE C CA  1 
ATOM   8873  C C   . ILE C 1 250 ? 152.459 164.345 200.133 1.00 17.17  ? 271 ILE C C   1 
ATOM   8874  O O   . ILE C 1 250 ? 151.839 164.739 199.137 1.00 17.17  ? 271 ILE C O   1 
ATOM   8875  C CB  . ILE C 1 250 ? 150.579 163.854 201.740 1.00 17.17  ? 271 ILE C CB  1 
ATOM   8876  C CG1 . ILE C 1 250 ? 149.926 164.298 203.049 1.00 17.17  ? 271 ILE C CG1 1 
ATOM   8877  C CG2 . ILE C 1 250 ? 150.796 162.350 201.728 1.00 17.17  ? 271 ILE C CG2 1 
ATOM   8878  C CD1 . ILE C 1 250 ? 148.600 163.633 203.327 1.00 17.17  ? 271 ILE C CD1 1 
ATOM   8879  N N   . LEU C 1 251 ? 153.621 163.697 200.070 1.00 15.93  ? 272 LEU C N   1 
ATOM   8880  C CA  . LEU C 1 251 ? 154.412 163.529 198.863 1.00 15.93  ? 272 LEU C CA  1 
ATOM   8881  C C   . LEU C 1 251 ? 154.557 162.044 198.564 1.00 15.93  ? 272 LEU C C   1 
ATOM   8882  O O   . LEU C 1 251 ? 154.600 161.220 199.482 1.00 15.93  ? 272 LEU C O   1 
ATOM   8883  C CB  . LEU C 1 251 ? 155.794 164.167 199.046 1.00 15.93  ? 272 LEU C CB  1 
ATOM   8884  C CG  . LEU C 1 251 ? 156.688 164.458 197.844 1.00 15.93  ? 272 LEU C CG  1 
ATOM   8885  C CD1 . LEU C 1 251 ? 156.239 165.723 197.154 1.00 15.93  ? 272 LEU C CD1 1 
ATOM   8886  C CD2 . LEU C 1 251 ? 158.133 164.582 198.288 1.00 15.93  ? 272 LEU C CD2 1 
ATOM   8887  N N   . ARG C 1 252 ? 154.621 161.700 197.281 1.00 21.34  ? 273 ARG C N   1 
ATOM   8888  C CA  . ARG C 1 252 ? 154.777 160.317 196.851 1.00 21.34  ? 273 ARG C CA  1 
ATOM   8889  C C   . ARG C 1 252 ? 155.990 160.208 195.942 1.00 21.34  ? 273 ARG C C   1 
ATOM   8890  O O   . ARG C 1 252 ? 156.081 160.922 194.939 1.00 21.34  ? 273 ARG C O   1 
ATOM   8891  C CB  . ARG C 1 252 ? 153.526 159.820 196.126 1.00 21.34  ? 273 ARG C CB  1 
ATOM   8892  C CG  . ARG C 1 252 ? 153.724 158.511 195.388 1.00 21.34  ? 273 ARG C CG  1 
ATOM   8893  C CD  . ARG C 1 252 ? 152.398 157.851 195.067 1.00 21.34  ? 273 ARG C CD  1 
ATOM   8894  N NE  . ARG C 1 252 ? 151.820 157.220 196.247 1.00 21.34  ? 273 ARG C NE  1 
ATOM   8895  C CZ  . ARG C 1 252 ? 150.776 156.404 196.226 1.00 21.34  ? 273 ARG C CZ  1 
ATOM   8896  N NH1 . ARG C 1 252 ? 150.176 156.079 195.093 1.00 21.34  ? 273 ARG C NH1 1 
ATOM   8897  N NH2 . ARG C 1 252 ? 150.326 155.896 197.370 1.00 21.34  ? 273 ARG C NH2 1 
ATOM   8898  N N   . VAL C 1 253 ? 156.916 159.315 196.288 1.00 20.84  ? 274 VAL C N   1 
ATOM   8899  C CA  . VAL C 1 253 ? 158.141 159.129 195.527 1.00 20.84  ? 274 VAL C CA  1 
ATOM   8900  C C   . VAL C 1 253 ? 158.170 157.710 194.970 1.00 20.84  ? 274 VAL C C   1 
ATOM   8901  O O   . VAL C 1 253 ? 157.439 156.823 195.415 1.00 20.84  ? 274 VAL C O   1 
ATOM   8902  C CB  . VAL C 1 253 ? 159.401 159.410 196.364 1.00 20.84  ? 274 VAL C CB  1 
ATOM   8903  C CG1 . VAL C 1 253 ? 159.434 160.862 196.804 1.00 20.84  ? 274 VAL C CG1 1 
ATOM   8904  C CG2 . VAL C 1 253 ? 159.436 158.495 197.561 1.00 20.84  ? 274 VAL C CG2 1 
ATOM   8905  N N   . ASN C 1 254 ? 159.032 157.510 193.977 1.00 25.28  ? 275 ASN C N   1 
ATOM   8906  C CA  . ASN C 1 254 ? 159.169 156.236 193.286 1.00 25.28  ? 275 ASN C CA  1 
ATOM   8907  C C   . ASN C 1 254 ? 160.522 155.629 193.623 1.00 25.28  ? 275 ASN C C   1 
ATOM   8908  O O   . ASN C 1 254 ? 161.562 156.252 193.386 1.00 25.28  ? 275 ASN C O   1 
ATOM   8909  C CB  . ASN C 1 254 ? 159.030 156.419 191.775 1.00 25.28  ? 275 ASN C CB  1 
ATOM   8910  C CG  . ASN C 1 254 ? 157.859 157.298 191.402 1.00 25.28  ? 275 ASN C CG  1 
ATOM   8911  O OD1 . ASN C 1 254 ? 156.702 156.927 191.597 1.00 25.28  ? 275 ASN C OD1 1 
ATOM   8912  N ND2 . ASN C 1 254 ? 158.152 158.474 190.863 1.00 25.28  ? 275 ASN C ND2 1 
ATOM   8913  N N   . ILE C 1 255 ? 160.507 154.417 194.167 1.00 30.70  ? 276 ILE C N   1 
ATOM   8914  C CA  . ILE C 1 255 ? 161.736 153.674 194.426 1.00 30.70  ? 276 ILE C CA  1 
ATOM   8915  C C   . ILE C 1 255 ? 162.264 153.162 193.092 1.00 30.70  ? 276 ILE C C   1 
ATOM   8916  O O   . ILE C 1 255 ? 161.555 152.427 192.390 1.00 30.70  ? 276 ILE C O   1 
ATOM   8917  C CB  . ILE C 1 255 ? 161.496 152.523 195.414 1.00 30.70  ? 276 ILE C CB  1 
ATOM   8918  C CG1 . ILE C 1 255 ? 161.082 153.074 196.777 1.00 30.70  ? 276 ILE C CG1 1 
ATOM   8919  C CG2 . ILE C 1 255 ? 162.736 151.654 195.536 1.00 30.70  ? 276 ILE C CG2 1 
ATOM   8920  C CD1 . ILE C 1 255 ? 160.356 152.076 197.638 1.00 30.70  ? 276 ILE C CD1 1 
ATOM   8921  N N   . PRO C 1 256 ? 163.482 153.517 192.699 1.00 33.77  ? 277 PRO C N   1 
ATOM   8922  C CA  . PRO C 1 256 ? 163.985 153.104 191.389 1.00 33.77  ? 277 PRO C CA  1 
ATOM   8923  C C   . PRO C 1 256 ? 164.466 151.661 191.387 1.00 33.77  ? 277 PRO C C   1 
ATOM   8924  O O   . PRO C 1 256 ? 164.897 151.110 192.401 1.00 33.77  ? 277 PRO C O   1 
ATOM   8925  C CB  . PRO C 1 256 ? 165.147 154.069 191.140 1.00 33.77  ? 277 PRO C CB  1 
ATOM   8926  C CG  . PRO C 1 256 ? 165.642 154.413 192.500 1.00 33.77  ? 277 PRO C CG  1 
ATOM   8927  C CD  . PRO C 1 256 ? 164.486 154.279 193.464 1.00 33.77  ? 277 PRO C CD  1 
ATOM   8928  N N   . ASP C 1 257 ? 164.383 151.054 190.205 1.00 37.73  ? 278 ASP C N   1 
ATOM   8929  C CA  . ASP C 1 257 ? 164.888 149.708 189.974 1.00 37.73  ? 278 ASP C CA  1 
ATOM   8930  C C   . ASP C 1 257 ? 165.647 149.707 188.658 1.00 37.73  ? 278 ASP C C   1 
ATOM   8931  O O   . ASP C 1 257 ? 165.110 150.128 187.630 1.00 37.73  ? 278 ASP C O   1 
ATOM   8932  C CB  . ASP C 1 257 ? 163.751 148.680 189.941 1.00 37.73  ? 278 ASP C CB  1 
ATOM   8933  C CG  . ASP C 1 257 ? 164.256 147.252 189.902 1.00 37.73  ? 278 ASP C CG  1 
ATOM   8934  O OD1 . ASP C 1 257 ? 165.400 147.012 190.341 1.00 37.73  ? 278 ASP C OD1 1 
ATOM   8935  O OD2 . ASP C 1 257 ? 163.508 146.369 189.435 1.00 37.73  ? 278 ASP C OD2 1 
ATOM   8936  N N   . LEU C 1 258 ? 166.891 149.242 188.693 1.00 33.67  ? 279 LEU C N   1 
ATOM   8937  C CA  . LEU C 1 258 ? 167.763 149.270 187.524 1.00 33.67  ? 279 LEU C CA  1 
ATOM   8938  C C   . LEU C 1 258 ? 167.575 147.979 186.738 1.00 33.67  ? 279 LEU C C   1 
ATOM   8939  O O   . LEU C 1 258 ? 167.979 146.904 187.194 1.00 33.67  ? 279 LEU C O   1 
ATOM   8940  C CB  . LEU C 1 258 ? 169.218 149.449 187.948 1.00 33.67  ? 279 LEU C CB  1 
ATOM   8941  C CG  . LEU C 1 258 ? 169.544 150.730 188.716 1.00 33.67  ? 279 LEU C CG  1 
ATOM   8942  C CD1 . LEU C 1 258 ? 171.013 150.762 189.097 1.00 33.67  ? 279 LEU C CD1 1 
ATOM   8943  C CD2 . LEU C 1 258 ? 169.171 151.958 187.902 1.00 33.67  ? 279 LEU C CD2 1 
ATOM   8944  N N   . ILE C 1 259 ? 166.964 148.079 185.560 1.00 37.02  ? 280 ILE C N   1 
ATOM   8945  C CA  . ILE C 1 259 ? 166.777 146.932 184.683 1.00 37.02  ? 280 ILE C CA  1 
ATOM   8946  C C   . ILE C 1 259 ? 167.827 147.028 183.582 1.00 37.02  ? 280 ILE C C   1 
ATOM   8947  O O   . ILE C 1 259 ? 168.359 148.108 183.292 1.00 37.02  ? 280 ILE C O   1 
ATOM   8948  C CB  . ILE C 1 259 ? 165.329 146.884 184.132 1.00 37.02  ? 280 ILE C CB  1 
ATOM   8949  C CG1 . ILE C 1 259 ? 164.964 145.487 183.618 1.00 37.02  ? 280 ILE C CG1 1 
ATOM   8950  C CG2 . ILE C 1 259 ? 165.106 147.923 183.040 1.00 37.02  ? 280 ILE C CG2 1 
ATOM   8951  C CD1 . ILE C 1 259 ? 164.911 144.434 184.702 1.00 37.02  ? 280 ILE C CD1 1 
ATOM   8952  N N   . GLU C 1 260 ? 168.181 145.884 183.007 1.00 41.78  ? 281 GLU C N   1 
ATOM   8953  C CA  . GLU C 1 260 ? 169.202 145.805 181.971 1.00 41.78  ? 281 GLU C CA  1 
ATOM   8954  C C   . GLU C 1 260 ? 168.534 145.491 180.640 1.00 41.78  ? 281 GLU C C   1 
ATOM   8955  O O   . GLU C 1 260 ? 167.794 144.507 180.531 1.00 41.78  ? 281 GLU C O   1 
ATOM   8956  C CB  . GLU C 1 260 ? 170.246 144.743 182.317 1.00 41.78  ? 281 GLU C CB  1 
ATOM   8957  C CG  . GLU C 1 260 ? 171.078 144.276 181.136 1.00 41.78  ? 281 GLU C CG  1 
ATOM   8958  C CD  . GLU C 1 260 ? 172.323 143.527 181.562 1.00 41.78  ? 281 GLU C CD  1 
ATOM   8959  O OE1 . GLU C 1 260 ? 172.612 143.493 182.777 1.00 41.78  ? 281 GLU C OE1 1 
ATOM   8960  O OE2 . GLU C 1 260 ? 173.008 142.966 180.682 1.00 41.78  ? 281 GLU C OE2 1 
ATOM   8961  N N   . VAL C 1 261 ? 168.780 146.333 179.645 1.00 39.45  ? 282 VAL C N   1 
ATOM   8962  C CA  . VAL C 1 261 ? 168.320 146.045 178.283 1.00 39.45  ? 282 VAL C CA  1 
ATOM   8963  C C   . VAL C 1 261 ? 169.114 144.863 177.726 1.00 39.45  ? 282 VAL C C   1 
ATOM   8964  O O   . VAL C 1 261 ? 170.345 144.801 177.908 1.00 39.45  ? 282 VAL C O   1 
ATOM   8965  C CB  . VAL C 1 261 ? 168.436 147.308 177.402 1.00 39.45  ? 282 VAL C CB  1 
ATOM   8966  C CG1 . VAL C 1 261 ? 169.826 147.934 177.462 1.00 39.45  ? 282 VAL C CG1 1 
ATOM   8967  C CG2 . VAL C 1 261 ? 168.045 147.028 175.954 1.00 39.45  ? 282 VAL C CG2 1 
ATOM   8968  N N   . PRO C 1 262 ? 168.462 143.857 177.136 1.00 50.24  ? 283 PRO C N   1 
ATOM   8969  C CA  . PRO C 1 262 ? 169.196 142.654 176.712 1.00 50.24  ? 283 PRO C CA  1 
ATOM   8970  C C   . PRO C 1 262 ? 169.990 142.886 175.433 1.00 50.24  ? 283 PRO C C   1 
ATOM   8971  O O   . PRO C 1 262 ? 169.477 143.438 174.456 1.00 50.24  ? 283 PRO C O   1 
ATOM   8972  C CB  . PRO C 1 262 ? 168.090 141.612 176.498 1.00 50.24  ? 283 PRO C CB  1 
ATOM   8973  C CG  . PRO C 1 262 ? 166.841 142.384 176.327 1.00 50.24  ? 283 PRO C CG  1 
ATOM   8974  C CD  . PRO C 1 262 ? 167.001 143.684 177.044 1.00 50.24  ? 283 PRO C CD  1 
ATOM   8975  N N   . GLY C 1 263 ? 171.246 142.451 175.450 1.00 59.01  ? 284 GLY C N   1 
ATOM   8976  C CA  . GLY C 1 263 ? 172.101 142.454 174.274 1.00 59.01  ? 284 GLY C CA  1 
ATOM   8977  C C   . GLY C 1 263 ? 172.504 143.811 173.739 1.00 59.01  ? 284 GLY C C   1 
ATOM   8978  O O   . GLY C 1 263 ? 172.598 143.983 172.518 1.00 59.01  ? 284 GLY C O   1 
ATOM   8979  N N   . ALA C 1 264 ? 172.760 144.777 174.617 1.00 52.73  ? 285 ALA C N   1 
ATOM   8980  C CA  . ALA C 1 264 ? 173.197 146.108 174.215 1.00 52.73  ? 285 ALA C CA  1 
ATOM   8981  C C   . ALA C 1 264 ? 174.553 146.401 174.839 1.00 52.73  ? 285 ALA C C   1 
ATOM   8982  O O   . ALA C 1 264 ? 174.734 146.227 176.048 1.00 52.73  ? 285 ALA C O   1 
ATOM   8983  C CB  . ALA C 1 264 ? 172.181 147.174 174.628 1.00 52.73  ? 285 ALA C CB  1 
ATOM   8984  N N   . VAL C 1 265 ? 175.500 146.844 174.013 1.00 37.06  ? 286 VAL C N   1 
ATOM   8985  C CA  . VAL C 1 265 ? 176.863 147.135 174.443 1.00 37.06  ? 286 VAL C CA  1 
ATOM   8986  C C   . VAL C 1 265 ? 177.187 148.578 174.077 1.00 37.06  ? 286 VAL C C   1 
ATOM   8987  O O   . VAL C 1 265 ? 177.011 148.986 172.923 1.00 37.06  ? 286 VAL C O   1 
ATOM   8988  C CB  . VAL C 1 265 ? 177.877 146.163 173.807 1.00 37.06  ? 286 VAL C CB  1 
ATOM   8989  C CG1 . VAL C 1 265 ? 179.307 146.577 174.122 1.00 37.06  ? 286 VAL C CG1 1 
ATOM   8990  C CG2 . VAL C 1 265 ? 177.629 144.741 174.288 1.00 37.06  ? 286 VAL C CG2 1 
ATOM   8991  N N   . ILE C 1 266 ? 177.648 149.348 175.060 1.00 30.26  ? 287 ILE C N   1 
ATOM   8992  C CA  . ILE C 1 266 ? 178.139 150.701 174.831 1.00 30.26  ? 287 ILE C CA  1 
ATOM   8993  C C   . ILE C 1 266 ? 179.634 150.626 174.557 1.00 30.26  ? 287 ILE C C   1 
ATOM   8994  O O   . ILE C 1 266 ? 180.384 150.012 175.326 1.00 30.26  ? 287 ILE C O   1 
ATOM   8995  C CB  . ILE C 1 266 ? 177.846 151.606 176.039 1.00 30.26  ? 287 ILE C CB  1 
ATOM   8996  C CG1 . ILE C 1 266 ? 176.387 151.467 176.475 1.00 30.26  ? 287 ILE C CG1 1 
ATOM   8997  C CG2 . ILE C 1 266 ? 178.171 153.053 175.714 1.00 30.26  ? 287 ILE C CG2 1 
ATOM   8998  C CD1 . ILE C 1 266 ? 175.393 151.917 175.439 1.00 30.26  ? 287 ILE C CD1 1 
ATOM   8999  N N   . GLN C 1 267 ? 180.072 151.247 173.464 1.00 28.97  ? 288 GLN C N   1 
ATOM   9000  C CA  . GLN C 1 267 ? 181.463 151.217 173.040 1.00 28.97  ? 288 GLN C CA  1 
ATOM   9001  C C   . GLN C 1 267 ? 181.998 152.638 172.955 1.00 28.97  ? 288 GLN C C   1 
ATOM   9002  O O   . GLN C 1 267 ? 181.335 153.525 172.404 1.00 28.97  ? 288 GLN C O   1 
ATOM   9003  C CB  . GLN C 1 267 ? 181.606 150.518 171.687 1.00 28.97  ? 288 GLN C CB  1 
ATOM   9004  C CG  . GLN C 1 267 ? 183.033 150.177 171.320 1.00 28.97  ? 288 GLN C CG  1 
ATOM   9005  C CD  . GLN C 1 267 ? 183.714 149.333 172.375 1.00 28.97  ? 288 GLN C CD  1 
ATOM   9006  O OE1 . GLN C 1 267 ? 183.220 148.269 172.748 1.00 28.97  ? 288 GLN C OE1 1 
ATOM   9007  N NE2 . GLN C 1 267 ? 184.853 149.805 172.865 1.00 28.97  ? 288 GLN C NE2 1 
ATOM   9008  N N   . GLU C 1 268 ? 183.192 152.846 173.499 1.00 30.91  ? 289 GLU C N   1 
ATOM   9009  C CA  . GLU C 1 268 ? 183.866 154.134 173.467 1.00 30.91  ? 289 GLU C CA  1 
ATOM   9010  C C   . GLU C 1 268 ? 185.011 154.109 172.462 1.00 30.91  ? 289 GLU C C   1 
ATOM   9011  O O   . GLU C 1 268 ? 185.513 153.050 172.079 1.00 30.91  ? 289 GLU C O   1 
ATOM   9012  C CB  . GLU C 1 268 ? 184.394 154.507 174.854 1.00 30.91  ? 289 GLU C CB  1 
ATOM   9013  C CG  . GLU C 1 268 ? 183.466 154.123 175.991 1.00 30.91  ? 289 GLU C CG  1 
ATOM   9014  C CD  . GLU C 1 268 ? 183.648 155.002 177.211 1.00 30.91  ? 289 GLU C CD  1 
ATOM   9015  O OE1 . GLU C 1 268 ? 184.623 155.780 177.243 1.00 30.91  ? 289 GLU C OE1 1 
ATOM   9016  O OE2 . GLU C 1 268 ? 182.814 154.915 178.136 1.00 30.91  ? 289 GLU C OE2 1 
ATOM   9017  N N   . PHE C 1 269 ? 185.420 155.301 172.035 1.00 29.11  ? 290 PHE C N   1 
ATOM   9018  C CA  . PHE C 1 269 ? 186.492 155.448 171.063 1.00 29.11  ? 290 PHE C CA  1 
ATOM   9019  C C   . PHE C 1 269 ? 187.419 156.575 171.489 1.00 29.11  ? 290 PHE C C   1 
ATOM   9020  O O   . PHE C 1 269 ? 186.963 157.621 171.958 1.00 29.11  ? 290 PHE C O   1 
ATOM   9021  C CB  . PHE C 1 269 ? 185.937 155.727 169.663 1.00 29.11  ? 290 PHE C CB  1 
ATOM   9022  C CG  . PHE C 1 269 ? 185.399 154.510 168.974 1.00 29.11  ? 290 PHE C CG  1 
ATOM   9023  C CD1 . PHE C 1 269 ? 186.259 153.530 168.503 1.00 29.11  ? 290 PHE C CD1 1 
ATOM   9024  C CD2 . PHE C 1 269 ? 184.035 154.339 168.804 1.00 29.11  ? 290 PHE C CD2 1 
ATOM   9025  C CE1 . PHE C 1 269 ? 185.769 152.403 167.868 1.00 29.11  ? 290 PHE C CE1 1 
ATOM   9026  C CE2 . PHE C 1 269 ? 183.537 153.214 168.172 1.00 29.11  ? 290 PHE C CE2 1 
ATOM   9027  C CZ  . PHE C 1 269 ? 184.406 152.246 167.703 1.00 29.11  ? 290 PHE C CZ  1 
ATOM   9028  N N   . ILE C 1 270 ? 188.719 156.353 171.322 1.00 30.87  ? 291 ILE C N   1 
ATOM   9029  C CA  . ILE C 1 270 ? 189.739 157.353 171.607 1.00 30.87  ? 291 ILE C CA  1 
ATOM   9030  C C   . ILE C 1 270 ? 190.229 157.922 170.285 1.00 30.87  ? 291 ILE C C   1 
ATOM   9031  O O   . ILE C 1 270 ? 190.602 157.170 169.375 1.00 30.87  ? 291 ILE C O   1 
ATOM   9032  C CB  . ILE C 1 270 ? 190.902 156.753 172.416 1.00 30.87  ? 291 ILE C CB  1 
ATOM   9033  C CG1 . ILE C 1 270 ? 190.377 156.058 173.671 1.00 30.87  ? 291 ILE C CG1 1 
ATOM   9034  C CG2 . ILE C 1 270 ? 191.905 157.829 172.793 1.00 30.87  ? 291 ILE C CG2 1 
ATOM   9035  C CD1 . ILE C 1 270 ? 191.442 155.314 174.435 1.00 30.87  ? 291 ILE C CD1 1 
ATOM   9036  N N   . LYS C 1 271 ? 190.218 159.245 170.169 1.00 30.80  ? 292 LYS C N   1 
ATOM   9037  C CA  . LYS C 1 271 ? 190.634 159.922 168.951 1.00 30.80  ? 292 LYS C CA  1 
ATOM   9038  C C   . LYS C 1 271 ? 192.034 160.490 169.134 1.00 30.80  ? 292 LYS C C   1 
ATOM   9039  O O   . LYS C 1 271 ? 192.291 161.226 170.092 1.00 30.80  ? 292 LYS C O   1 
ATOM   9040  C CB  . LYS C 1 271 ? 189.654 161.038 168.588 1.00 30.80  ? 292 LYS C CB  1 
ATOM   9041  C CG  . LYS C 1 271 ? 188.269 160.548 168.204 1.00 30.80  ? 292 LYS C CG  1 
ATOM   9042  C CD  . LYS C 1 271 ? 187.416 161.685 167.669 1.00 30.80  ? 292 LYS C CD  1 
ATOM   9043  C CE  . LYS C 1 271 ? 187.014 162.641 168.778 1.00 30.80  ? 292 LYS C CE  1 
ATOM   9044  N NZ  . LYS C 1 271 ? 186.116 163.718 168.281 1.00 30.80  ? 292 LYS C NZ  1 
ATOM   9045  N N   . ILE C 1 272 ? 192.932 160.142 168.220 1.00 40.37  ? 293 ILE C N   1 
ATOM   9046  C CA  . ILE C 1 272 ? 194.277 160.692 168.196 1.00 40.37  ? 293 ILE C CA  1 
ATOM   9047  C C   . ILE C 1 272 ? 194.433 161.524 166.932 1.00 40.37  ? 293 ILE C C   1 
ATOM   9048  O O   . ILE C 1 272 ? 193.653 161.417 165.980 1.00 40.37  ? 293 ILE C O   1 
ATOM   9049  C CB  . ILE C 1 272 ? 195.362 159.598 168.274 1.00 40.37  ? 293 ILE C CB  1 
ATOM   9050  C CG1 . ILE C 1 272 ? 195.362 158.752 167.000 1.00 40.37  ? 293 ILE C CG1 1 
ATOM   9051  C CG2 . ILE C 1 272 ? 195.156 158.732 169.505 1.00 40.37  ? 293 ILE C CG2 1 
ATOM   9052  C CD1 . ILE C 1 272 ? 196.375 157.628 167.007 1.00 40.37  ? 293 ILE C CD1 1 
ATOM   9053  N N   . GLY C 1 273 ? 195.454 162.373 166.931 1.00 53.84  ? 294 GLY C N   1 
ATOM   9054  C CA  . GLY C 1 273 ? 195.727 163.256 165.811 1.00 53.84  ? 294 GLY C CA  1 
ATOM   9055  C C   . GLY C 1 273 ? 196.813 162.685 164.917 1.00 53.84  ? 294 GLY C C   1 
ATOM   9056  O O   . GLY C 1 273 ? 197.850 162.228 165.395 1.00 53.84  ? 294 GLY C O   1 
ATOM   9057  N N   . TYR C 1 274 ? 196.559 162.718 163.613 1.00 66.15  ? 295 TYR C N   1 
ATOM   9058  C CA  . TYR C 1 274 ? 197.500 162.224 162.624 1.00 66.15  ? 295 TYR C CA  1 
ATOM   9059  C C   . TYR C 1 274 ? 197.992 163.375 161.757 1.00 66.15  ? 295 TYR C C   1 
ATOM   9060  O O   . TYR C 1 274 ? 197.273 164.352 161.517 1.00 66.15  ? 295 TYR C O   1 
ATOM   9061  C CB  . TYR C 1 274 ? 196.881 161.114 161.753 1.00 66.15  ? 295 TYR C CB  1 
ATOM   9062  C CG  . TYR C 1 274 ? 195.725 161.530 160.867 1.00 66.15  ? 295 TYR C CG  1 
ATOM   9063  C CD1 . TYR C 1 274 ? 194.432 161.609 161.370 1.00 66.15  ? 295 TYR C CD1 1 
ATOM   9064  C CD2 . TYR C 1 274 ? 195.922 161.805 159.518 1.00 66.15  ? 295 TYR C CD2 1 
ATOM   9065  C CE1 . TYR C 1 274 ? 193.371 161.976 160.562 1.00 66.15  ? 295 TYR C CE1 1 
ATOM   9066  C CE2 . TYR C 1 274 ? 194.868 162.173 158.702 1.00 66.15  ? 295 TYR C CE2 1 
ATOM   9067  C CZ  . TYR C 1 274 ? 193.596 162.256 159.230 1.00 66.15  ? 295 TYR C CZ  1 
ATOM   9068  O OH  . TYR C 1 274 ? 192.548 162.620 158.418 1.00 66.15  ? 295 TYR C OH  1 
ATOM   9069  N N   . ASN C 1 275 ? 199.235 163.247 161.301 1.00 73.08  ? 296 ASN C N   1 
ATOM   9070  C CA  . ASN C 1 275 ? 199.911 164.282 160.528 1.00 73.08  ? 296 ASN C CA  1 
ATOM   9071  C C   . ASN C 1 275 ? 199.800 163.935 159.048 1.00 73.08  ? 296 ASN C C   1 
ATOM   9072  O O   . ASN C 1 275 ? 200.440 162.991 158.573 1.00 73.08  ? 296 ASN C O   1 
ATOM   9073  C CB  . ASN C 1 275 ? 201.370 164.406 160.959 1.00 73.08  ? 296 ASN C CB  1 
ATOM   9074  C CG  . ASN C 1 275 ? 201.983 165.735 160.570 1.00 73.08  ? 296 ASN C CG  1 
ATOM   9075  O OD1 . ASN C 1 275 ? 201.340 166.566 159.931 1.00 73.08  ? 296 ASN C OD1 1 
ATOM   9076  N ND2 . ASN C 1 275 ? 203.235 165.943 160.958 1.00 73.08  ? 296 ASN C ND2 1 
ATOM   9077  N N   . PHE C 1 276 ? 198.988 164.700 158.324 1.00 70.98  ? 297 PHE C N   1 
ATOM   9078  C CA  . PHE C 1 276 ? 198.812 164.516 156.892 1.00 70.98  ? 297 PHE C CA  1 
ATOM   9079  C C   . PHE C 1 276 ? 198.739 165.882 156.230 1.00 70.98  ? 297 PHE C C   1 
ATOM   9080  O O   . PHE C 1 276 ? 198.181 166.826 156.799 1.00 70.98  ? 297 PHE C O   1 
ATOM   9081  C CB  . PHE C 1 276 ? 197.549 163.704 156.581 1.00 70.98  ? 297 PHE C CB  1 
ATOM   9082  C CG  . PHE C 1 276 ? 197.360 163.412 155.120 1.00 70.98  ? 297 PHE C CG  1 
ATOM   9083  C CD1 . PHE C 1 276 ? 198.137 162.454 154.486 1.00 70.98  ? 297 PHE C CD1 1 
ATOM   9084  C CD2 . PHE C 1 276 ? 196.407 164.095 154.380 1.00 70.98  ? 297 PHE C CD2 1 
ATOM   9085  C CE1 . PHE C 1 276 ? 197.966 162.181 153.138 1.00 70.98  ? 297 PHE C CE1 1 
ATOM   9086  C CE2 . PHE C 1 276 ? 196.230 163.829 153.033 1.00 70.98  ? 297 PHE C CE2 1 
ATOM   9087  C CZ  . PHE C 1 276 ? 197.011 162.871 152.412 1.00 70.98  ? 297 PHE C CZ  1 
ATOM   9088  N N   . GLY C 1 277 ? 199.328 165.984 155.038 1.00 73.15  ? 298 GLY C N   1 
ATOM   9089  C CA  . GLY C 1 277 ? 199.318 167.219 154.275 1.00 73.15  ? 298 GLY C CA  1 
ATOM   9090  C C   . GLY C 1 277 ? 200.062 168.366 154.917 1.00 73.15  ? 298 GLY C C   1 
ATOM   9091  O O   . GLY C 1 277 ? 199.781 169.527 154.608 1.00 73.15  ? 298 GLY C O   1 
ATOM   9092  N N   . GLY C 1 278 ? 201.008 168.074 155.807 1.00 73.31  ? 299 GLY C N   1 
ATOM   9093  C CA  . GLY C 1 278 ? 201.623 169.119 156.595 1.00 73.31  ? 299 GLY C CA  1 
ATOM   9094  C C   . GLY C 1 278 ? 200.728 169.699 157.665 1.00 73.31  ? 299 GLY C C   1 
ATOM   9095  O O   . GLY C 1 278 ? 200.944 170.838 158.086 1.00 73.31  ? 299 GLY C O   1 
ATOM   9096  N N   . SER C 1 279 ? 199.722 168.952 158.119 1.00 78.62  ? 300 SER C N   1 
ATOM   9097  C CA  . SER C 1 279 ? 198.785 169.474 159.103 1.00 78.62  ? 300 SER C CA  1 
ATOM   9098  C C   . SER C 1 279 ? 198.321 168.356 160.027 1.00 78.62  ? 300 SER C C   1 
ATOM   9099  O O   . SER C 1 279 ? 198.463 167.169 159.724 1.00 78.62  ? 300 SER C O   1 
ATOM   9100  C CB  . SER C 1 279 ? 197.580 170.139 158.431 1.00 78.62  ? 300 SER C CB  1 
ATOM   9101  O OG  . SER C 1 279 ? 196.658 170.591 159.403 1.00 78.62  ? 300 SER C OG  1 
ATOM   9102  N N   . LEU C 1 280 ? 197.757 168.755 161.164 1.00 75.95  ? 301 LEU C N   1 
ATOM   9103  C CA  . LEU C 1 280 ? 197.285 167.825 162.182 1.00 75.95  ? 301 LEU C CA  1 
ATOM   9104  C C   . LEU C 1 280 ? 195.769 167.701 162.086 1.00 75.95  ? 301 LEU C C   1 
ATOM   9105  O O   . LEU C 1 280 ? 195.052 168.707 162.155 1.00 75.95  ? 301 LEU C O   1 
ATOM   9106  C CB  . LEU C 1 280 ? 197.702 168.291 163.577 1.00 75.95  ? 301 LEU C CB  1 
ATOM   9107  C CG  . LEU C 1 280 ? 197.831 167.218 164.661 1.00 75.95  ? 301 LEU C CG  1 
ATOM   9108  C CD1 . LEU C 1 280 ? 198.663 166.044 164.168 1.00 75.95  ? 301 LEU C CD1 1 
ATOM   9109  C CD2 . LEU C 1 280 ? 198.433 167.811 165.926 1.00 75.95  ? 301 LEU C CD2 1 
ATOM   9110  N N   . TRP C 1 281 ? 195.286 166.468 161.938 1.00 69.95  ? 302 TRP C N   1 
ATOM   9111  C CA  . TRP C 1 281 ? 193.869 166.205 161.745 1.00 69.95  ? 302 TRP C CA  1 
ATOM   9112  C C   . TRP C 1 281 ? 193.404 165.132 162.720 1.00 69.95  ? 302 TRP C C   1 
ATOM   9113  O O   . TRP C 1 281 ? 194.191 164.308 163.191 1.00 69.95  ? 302 TRP C O   1 
ATOM   9114  C CB  . TRP C 1 281 ? 193.561 165.740 160.311 1.00 69.95  ? 302 TRP C CB  1 
ATOM   9115  C CG  . TRP C 1 281 ? 194.132 166.595 159.216 1.00 69.95  ? 302 TRP C CG  1 
ATOM   9116  C CD1 . TRP C 1 281 ? 195.416 166.585 158.751 1.00 69.95  ? 302 TRP C CD1 1 
ATOM   9117  C CD2 . TRP C 1 281 ? 193.428 167.560 158.425 1.00 69.95  ? 302 TRP C CD2 1 
ATOM   9118  N NE1 . TRP C 1 281 ? 195.558 167.494 157.732 1.00 69.95  ? 302 TRP C NE1 1 
ATOM   9119  C CE2 . TRP C 1 281 ? 194.352 168.106 157.512 1.00 69.95  ? 302 TRP C CE2 1 
ATOM   9120  C CE3 . TRP C 1 281 ? 192.108 168.021 158.405 1.00 69.95  ? 302 TRP C CE3 1 
ATOM   9121  C CZ2 . TRP C 1 281 ? 193.999 169.089 156.589 1.00 69.95  ? 302 TRP C CZ2 1 
ATOM   9122  C CZ3 . TRP C 1 281 ? 191.759 168.997 157.488 1.00 69.95  ? 302 TRP C CZ3 1 
ATOM   9123  C CH2 . TRP C 1 281 ? 192.701 169.521 156.594 1.00 69.95  ? 302 TRP C CH2 1 
ATOM   9124  N N   . MET C 1 282 ? 192.107 165.156 163.024 1.00 62.09  ? 303 MET C N   1 
ATOM   9125  C CA  . MET C 1 282 ? 191.478 163.995 163.645 1.00 62.09  ? 303 MET C CA  1 
ATOM   9126  C C   . MET C 1 282 ? 190.221 163.625 162.871 1.00 62.09  ? 303 MET C C   1 
ATOM   9127  O O   . MET C 1 282 ? 189.559 164.507 162.311 1.00 62.09  ? 303 MET C O   1 
ATOM   9128  C CB  . MET C 1 282 ? 191.099 164.222 165.121 1.00 62.09  ? 303 MET C CB  1 
ATOM   9129  C CG  . MET C 1 282 ? 192.233 164.603 166.044 1.00 62.09  ? 303 MET C CG  1 
ATOM   9130  S SD  . MET C 1 282 ? 191.678 165.906 167.147 1.00 62.09  ? 303 MET C SD  1 
ATOM   9131  C CE  . MET C 1 282 ? 191.274 167.153 165.944 1.00 62.09  ? 303 MET C CE  1 
ATOM   9132  N N   . PRO C 1 283 ? 189.871 162.339 162.810 1.00 52.48  ? 304 PRO C N   1 
ATOM   9133  C CA  . PRO C 1 283 ? 188.580 161.960 162.229 1.00 52.48  ? 304 PRO C CA  1 
ATOM   9134  C C   . PRO C 1 283 ? 187.420 162.418 163.099 1.00 52.48  ? 304 PRO C C   1 
ATOM   9135  O O   . PRO C 1 283 ? 187.523 162.495 164.325 1.00 52.48  ? 304 PRO C O   1 
ATOM   9136  C CB  . PRO C 1 283 ? 188.652 160.431 162.156 1.00 52.48  ? 304 PRO C CB  1 
ATOM   9137  C CG  . PRO C 1 283 ? 189.681 160.046 163.154 1.00 52.48  ? 304 PRO C CG  1 
ATOM   9138  C CD  . PRO C 1 283 ? 190.680 161.159 163.165 1.00 52.48  ? 304 PRO C CD  1 
ATOM   9139  N N   . THR C 1 284 ? 186.305 162.727 162.441 1.00 60.12  ? 305 THR C N   1 
ATOM   9140  C CA  . THR C 1 284 ? 185.112 163.242 163.110 1.00 60.12  ? 305 THR C CA  1 
ATOM   9141  C C   . THR C 1 284 ? 184.135 162.085 163.290 1.00 60.12  ? 305 THR C C   1 
ATOM   9142  O O   . THR C 1 284 ? 183.283 161.826 162.439 1.00 60.12  ? 305 THR C O   1 
ATOM   9143  C CB  . THR C 1 284 ? 184.490 164.383 162.314 1.00 60.12  ? 305 THR C CB  1 
ATOM   9144  O OG1 . THR C 1 284 ? 184.008 163.884 161.061 1.00 60.12  ? 305 THR C OG1 1 
ATOM   9145  C CG2 . THR C 1 284 ? 185.520 165.470 162.057 1.00 60.12  ? 305 THR C CG2 1 
ATOM   9146  N N   . ILE C 1 285 ? 184.264 161.387 164.412 1.00 48.89  ? 306 ILE C N   1 
ATOM   9147  C CA  . ILE C 1 285 ? 183.386 160.268 164.743 1.00 48.89  ? 306 ILE C CA  1 
ATOM   9148  C C   . ILE C 1 285 ? 182.809 160.507 166.134 1.00 48.89  ? 306 ILE C C   1 
ATOM   9149  O O   . ILE C 1 285 ? 183.462 161.151 166.967 1.00 48.89  ? 306 ILE C O   1 
ATOM   9150  C CB  . ILE C 1 285 ? 184.136 158.928 164.666 1.00 48.89  ? 306 ILE C CB  1 
ATOM   9151  C CG1 . ILE C 1 285 ? 185.463 159.010 165.423 1.00 48.89  ? 306 ILE C CG1 1 
ATOM   9152  C CG2 . ILE C 1 285 ? 184.366 158.521 163.219 1.00 48.89  ? 306 ILE C CG2 1 
ATOM   9153  C CD1 . ILE C 1 285 ? 186.159 157.678 165.576 1.00 48.89  ? 306 ILE C CD1 1 
ATOM   9154  N N   . PRO C 1 286 ? 181.589 160.050 166.419 1.00 48.05  ? 307 PRO C N   1 
ATOM   9155  C CA  . PRO C 1 286 ? 181.076 160.139 167.790 1.00 48.05  ? 307 PRO C CA  1 
ATOM   9156  C C   . PRO C 1 286 ? 181.820 159.198 168.723 1.00 48.05  ? 307 PRO C C   1 
ATOM   9157  O O   . PRO C 1 286 ? 182.301 158.136 168.322 1.00 48.05  ? 307 PRO C O   1 
ATOM   9158  C CB  . PRO C 1 286 ? 179.604 159.735 167.648 1.00 48.05  ? 307 PRO C CB  1 
ATOM   9159  C CG  . PRO C 1 286 ? 179.550 158.940 166.389 1.00 48.05  ? 307 PRO C CG  1 
ATOM   9160  C CD  . PRO C 1 286 ? 180.570 159.549 165.482 1.00 48.05  ? 307 PRO C CD  1 
ATOM   9161  N N   . ASN C 1 287 ? 181.918 159.611 169.989 1.00 38.44  ? 308 ASN C N   1 
ATOM   9162  C CA  . ASN C 1 287 ? 182.680 158.836 170.962 1.00 38.44  ? 308 ASN C CA  1 
ATOM   9163  C C   . ASN C 1 287 ? 181.931 157.581 171.393 1.00 38.44  ? 308 ASN C C   1 
ATOM   9164  O O   . ASN C 1 287 ? 182.538 156.517 171.554 1.00 38.44  ? 308 ASN C O   1 
ATOM   9165  C CB  . ASN C 1 287 ? 183.014 159.703 172.175 1.00 38.44  ? 308 ASN C CB  1 
ATOM   9166  C CG  . ASN C 1 287 ? 183.920 160.864 171.828 1.00 38.44  ? 308 ASN C CG  1 
ATOM   9167  O OD1 . ASN C 1 287 ? 185.075 160.672 171.451 1.00 38.44  ? 308 ASN C OD1 1 
ATOM   9168  N ND2 . ASN C 1 287 ? 183.400 162.078 171.953 1.00 38.44  ? 308 ASN C ND2 1 
ATOM   9169  N N   . LYS C 1 288 ? 180.618 157.680 171.576 1.00 36.15  ? 309 LYS C N   1 
ATOM   9170  C CA  . LYS C 1 288 ? 179.813 156.599 172.127 1.00 36.15  ? 309 LYS C CA  1 
ATOM   9171  C C   . LYS C 1 288 ? 178.985 155.955 171.025 1.00 36.15  ? 309 LYS C C   1 
ATOM   9172  O O   . LYS C 1 288 ? 178.301 156.652 170.269 1.00 36.15  ? 309 LYS C O   1 
ATOM   9173  C CB  . LYS C 1 288 ? 178.900 157.121 173.237 1.00 36.15  ? 309 LYS C CB  1 
ATOM   9174  C CG  . LYS C 1 288 ? 179.637 157.536 174.498 1.00 36.15  ? 309 LYS C CG  1 
ATOM   9175  C CD  . LYS C 1 288 ? 178.726 158.301 175.439 1.00 36.15  ? 309 LYS C CD  1 
ATOM   9176  C CE  . LYS C 1 288 ? 178.244 159.595 174.806 1.00 36.15  ? 309 LYS C CE  1 
ATOM   9177  N NZ  . LYS C 1 288 ? 179.357 160.561 174.603 1.00 36.15  ? 309 LYS C NZ  1 
ATOM   9178  N N   . ILE C 1 289 ? 179.050 154.629 170.932 1.00 38.05  ? 310 ILE C N   1 
ATOM   9179  C CA  . ILE C 1 289 ? 178.273 153.862 169.963 1.00 38.05  ? 310 ILE C CA  1 
ATOM   9180  C C   . ILE C 1 289 ? 177.557 152.748 170.710 1.00 38.05  ? 310 ILE C C   1 
ATOM   9181  O O   . ILE C 1 289 ? 178.200 151.947 171.397 1.00 38.05  ? 310 ILE C O   1 
ATOM   9182  C CB  . ILE C 1 289 ? 179.157 153.283 168.843 1.00 38.05  ? 310 ILE C CB  1 
ATOM   9183  C CG1 . ILE C 1 289 ? 179.718 154.400 167.961 1.00 38.05  ? 310 ILE C CG1 1 
ATOM   9184  C CG2 . ILE C 1 289 ? 178.391 152.271 168.001 1.00 38.05  ? 310 ILE C CG2 1 
ATOM   9185  C CD1 . ILE C 1 289 ? 178.661 155.169 167.205 1.00 38.05  ? 310 ILE C CD1 1 
ATOM   9186  N N   . ILE C 1 290 ? 176.235 152.689 170.579 1.00 45.18  ? 311 ILE C N   1 
ATOM   9187  C CA  . ILE C 1 290 ? 175.452 151.588 171.127 1.00 45.18  ? 311 ILE C CA  1 
ATOM   9188  C C   . ILE C 1 290 ? 175.284 150.523 170.048 1.00 45.18  ? 311 ILE C C   1 
ATOM   9189  O O   . ILE C 1 290 ? 174.981 150.832 168.887 1.00 45.18  ? 311 ILE C O   1 
ATOM   9190  C CB  . ILE C 1 290 ? 174.107 152.078 171.706 1.00 45.18  ? 311 ILE C CB  1 
ATOM   9191  C CG1 . ILE C 1 290 ? 173.390 150.949 172.454 1.00 45.18  ? 311 ILE C CG1 1 
ATOM   9192  C CG2 . ILE C 1 290 ? 173.225 152.802 170.684 1.00 45.18  ? 311 ILE C CG2 1 
ATOM   9193  C CD1 . ILE C 1 290 ? 172.242 151.430 173.313 1.00 45.18  ? 311 ILE C CD1 1 
ATOM   9194  N N   . ILE C 1 291 ? 175.590 149.278 170.403 1.00 54.01  ? 312 ILE C N   1 
ATOM   9195  C CA  . ILE C 1 291 ? 175.509 148.148 169.487 1.00 54.01  ? 312 ILE C CA  1 
ATOM   9196  C C   . ILE C 1 291 ? 174.531 147.140 170.070 1.00 54.01  ? 312 ILE C C   1 
ATOM   9197  O O   . ILE C 1 291 ? 174.672 146.731 171.229 1.00 54.01  ? 312 ILE C O   1 
ATOM   9198  C CB  . ILE C 1 291 ? 176.889 147.506 169.250 1.00 54.01  ? 312 ILE C CB  1 
ATOM   9199  C CG1 . ILE C 1 291 ? 177.869 148.539 168.689 1.00 54.01  ? 312 ILE C CG1 1 
ATOM   9200  C CG2 . ILE C 1 291 ? 176.775 146.321 168.305 1.00 54.01  ? 312 ILE C CG2 1 
ATOM   9201  C CD1 . ILE C 1 291 ? 179.290 148.045 168.584 1.00 54.01  ? 312 ILE C CD1 1 
ATOM   9202  N N   . ARG C 1 292 ? 173.537 146.748 169.272 1.00 83.29  ? 313 ARG C N   1 
ATOM   9203  C CA  . ARG C 1 292 ? 172.520 145.803 169.729 1.00 83.29  ? 313 ARG C CA  1 
ATOM   9204  C C   . ARG C 1 292 ? 172.045 145.016 168.510 1.00 83.29  ? 313 ARG C C   1 
ATOM   9205  O O   . ARG C 1 292 ? 171.222 145.511 167.735 1.00 83.29  ? 313 ARG C O   1 
ATOM   9206  C CB  . ARG C 1 292 ? 171.372 146.526 170.420 1.00 83.29  ? 313 ARG C CB  1 
ATOM   9207  C CG  . ARG C 1 292 ? 170.228 145.624 170.871 1.00 83.29  ? 313 ARG C CG  1 
ATOM   9208  C CD  . ARG C 1 292 ? 169.122 146.392 171.596 1.00 83.29  ? 313 ARG C CD  1 
ATOM   9209  N NE  . ARG C 1 292 ? 168.580 147.499 170.815 1.00 83.29  ? 313 ARG C NE  1 
ATOM   9210  C CZ  . ARG C 1 292 ? 168.788 148.782 171.082 1.00 83.29  ? 313 ARG C CZ  1 
ATOM   9211  N NH1 . ARG C 1 292 ? 169.526 149.163 172.112 1.00 83.29  ? 313 ARG C NH1 1 
ATOM   9212  N NH2 . ARG C 1 292 ? 168.246 149.706 170.293 1.00 83.29  ? 313 ARG C NH2 1 
ATOM   9213  N N   . GLY C 1 293 ? 172.564 143.799 168.355 1.00 87.64  ? 314 GLY C N   1 
ATOM   9214  C CA  . GLY C 1 293 ? 172.195 142.934 167.249 1.00 87.64  ? 314 GLY C CA  1 
ATOM   9215  C C   . GLY C 1 293 ? 172.601 143.453 165.885 1.00 87.64  ? 314 GLY C C   1 
ATOM   9216  O O   . GLY C 1 293 ? 171.787 143.447 164.954 1.00 87.64  ? 314 GLY C O   1 
ATOM   9217  N N   . TYR C 1 294 ? 173.857 143.913 165.780 1.00 86.89  ? 315 TYR C N   1 
ATOM   9218  C CA  . TYR C 1 294 ? 174.437 144.527 164.572 1.00 86.89  ? 315 TYR C CA  1 
ATOM   9219  C C   . TYR C 1 294 ? 173.637 145.745 164.113 1.00 86.89  ? 315 TYR C C   1 
ATOM   9220  O O   . TYR C 1 294 ? 173.505 146.010 162.916 1.00 86.89  ? 315 TYR C O   1 
ATOM   9221  C CB  . TYR C 1 294 ? 174.602 143.525 163.416 1.00 86.89  ? 315 TYR C CB  1 
ATOM   9222  C CG  . TYR C 1 294 ? 175.268 142.196 163.739 1.00 86.89  ? 315 TYR C CG  1 
ATOM   9223  C CD1 . TYR C 1 294 ? 176.244 142.090 164.730 1.00 86.89  ? 315 TYR C CD1 1 
ATOM   9224  C CD2 . TYR C 1 294 ? 174.919 141.044 163.040 1.00 86.89  ? 315 TYR C CD2 1 
ATOM   9225  C CE1 . TYR C 1 294 ? 176.845 140.878 165.015 1.00 86.89  ? 315 TYR C CE1 1 
ATOM   9226  C CE2 . TYR C 1 294 ? 175.517 139.827 163.319 1.00 86.89  ? 315 TYR C CE2 1 
ATOM   9227  C CZ  . TYR C 1 294 ? 176.478 139.752 164.307 1.00 86.89  ? 315 TYR C CZ  1 
ATOM   9228  O OH  . TYR C 1 294 ? 177.075 138.545 164.589 1.00 86.89  ? 315 TYR C OH  1 
ATOM   9229  N N   . HIS C 1 295 ? 173.108 146.500 165.073 1.00 81.50  ? 316 HIS C N   1 
ATOM   9230  C CA  . HIS C 1 295 ? 172.372 147.727 164.796 1.00 81.50  ? 316 HIS C CA  1 
ATOM   9231  C C   . HIS C 1 295 ? 173.030 148.858 165.568 1.00 81.50  ? 316 HIS C C   1 
ATOM   9232  O O   . HIS C 1 295 ? 173.134 148.796 166.798 1.00 81.50  ? 316 HIS C O   1 
ATOM   9233  C CB  . HIS C 1 295 ? 170.897 147.595 165.181 1.00 81.50  ? 316 HIS C CB  1 
ATOM   9234  C CG  . HIS C 1 295 ? 169.998 148.544 164.453 1.00 81.50  ? 316 HIS C CG  1 
ATOM   9235  N ND1 . HIS C 1 295 ? 168.625 148.492 164.551 1.00 81.50  ? 316 HIS C ND1 1 
ATOM   9236  C CD2 . HIS C 1 295 ? 170.278 149.569 163.614 1.00 81.50  ? 316 HIS C CD2 1 
ATOM   9237  C CE1 . HIS C 1 295 ? 168.096 149.446 163.804 1.00 81.50  ? 316 HIS C CE1 1 
ATOM   9238  N NE2 . HIS C 1 295 ? 169.078 150.113 163.225 1.00 81.50  ? 316 HIS C NE2 1 
ATOM   9239  N N   . LEU C 1 296 ? 173.470 149.884 164.851 1.00 62.53  ? 317 LEU C N   1 
ATOM   9240  C CA  . LEU C 1 296 ? 174.206 150.991 165.441 1.00 62.53  ? 317 LEU C CA  1 
ATOM   9241  C C   . LEU C 1 296 ? 173.302 152.208 165.578 1.00 62.53  ? 317 LEU C C   1 
ATOM   9242  O O   . LEU C 1 296 ? 172.560 152.552 164.654 1.00 62.53  ? 317 LEU C O   1 
ATOM   9243  C CB  . LEU C 1 296 ? 175.429 151.339 164.590 1.00 62.53  ? 317 LEU C CB  1 
ATOM   9244  C CG  . LEU C 1 296 ? 176.268 150.181 164.049 1.00 62.53  ? 317 LEU C CG  1 
ATOM   9245  C CD1 . LEU C 1 296 ? 177.370 150.704 163.141 1.00 62.53  ? 317 LEU C CD1 1 
ATOM   9246  C CD2 . LEU C 1 296 ? 176.853 149.359 165.182 1.00 62.53  ? 317 LEU C CD2 1 
ATOM   9247  N N   . SER C 1 297 ? 173.360 152.851 166.743 1.00 50.68  ? 318 SER C N   1 
ATOM   9248  C CA  . SER C 1 297 ? 172.620 154.078 166.997 1.00 50.68  ? 318 SER C CA  1 
ATOM   9249  C C   . SER C 1 297 ? 173.492 155.004 167.835 1.00 50.68  ? 318 SER C C   1 
ATOM   9250  O O   . SER C 1 297 ? 174.651 154.700 168.131 1.00 50.68  ? 318 SER C O   1 
ATOM   9251  C CB  . SER C 1 297 ? 171.280 153.789 167.684 1.00 50.68  ? 318 SER C CB  1 
ATOM   9252  O OG  . SER C 1 297 ? 170.454 152.972 166.872 1.00 50.68  ? 318 SER C OG  1 
ATOM   9253  N N   . LEU C 1 298 ? 172.927 156.143 168.224 1.00 47.66  ? 319 LEU C N   1 
ATOM   9254  C CA  . LEU C 1 298 ? 173.651 157.170 168.958 1.00 47.66  ? 319 LEU C CA  1 
ATOM   9255  C C   . LEU C 1 298 ? 172.932 157.489 170.260 1.00 47.66  ? 319 LEU C C   1 
ATOM   9256  O O   . LEU C 1 298 ? 171.699 157.530 170.306 1.00 47.66  ? 319 LEU C O   1 
ATOM   9257  C CB  . LEU C 1 298 ? 173.794 158.445 168.124 1.00 47.66  ? 319 LEU C CB  1 
ATOM   9258  C CG  . LEU C 1 298 ? 174.617 158.312 166.844 1.00 47.66  ? 319 LEU C CG  1 
ATOM   9259  C CD1 . LEU C 1 298 ? 174.607 159.613 166.057 1.00 47.66  ? 319 LEU C CD1 1 
ATOM   9260  C CD2 . LEU C 1 298 ? 176.034 157.891 167.175 1.00 47.66  ? 319 LEU C CD2 1 
ATOM   9261  N N   . ILE C 1 299 ? 173.712 157.716 171.318 1.00 41.07  ? 320 ILE C N   1 
ATOM   9262  C CA  . ILE C 1 299 ? 173.184 158.120 172.613 1.00 41.07  ? 320 ILE C CA  1 
ATOM   9263  C C   . ILE C 1 299 ? 173.919 159.373 173.065 1.00 41.07  ? 320 ILE C C   1 
ATOM   9264  O O   . ILE C 1 299 ? 175.050 159.642 172.655 1.00 41.07  ? 320 ILE C O   1 
ATOM   9265  C CB  . ILE C 1 299 ? 173.315 157.013 173.682 1.00 41.07  ? 320 ILE C CB  1 
ATOM   9266  C CG1 . ILE C 1 299 ? 174.755 156.511 173.755 1.00 41.07  ? 320 ILE C CG1 1 
ATOM   9267  C CG2 . ILE C 1 299 ? 172.366 155.862 173.390 1.00 41.07  ? 320 ILE C CG2 1 
ATOM   9268  C CD1 . ILE C 1 299 ? 175.023 155.629 174.944 1.00 41.07  ? 320 ILE C CD1 1 
ATOM   9269  N N   . ASP C 1 300 ? 173.255 160.147 173.918 1.00 39.71  ? 321 ASP C N   1 
ATOM   9270  C CA  . ASP C 1 300 ? 173.845 161.331 174.526 1.00 39.71  ? 321 ASP C CA  1 
ATOM   9271  C C   . ASP C 1 300 ? 173.890 161.146 176.036 1.00 39.71  ? 321 ASP C C   1 
ATOM   9272  O O   . ASP C 1 300 ? 172.867 160.859 176.666 1.00 39.71  ? 321 ASP C O   1 
ATOM   9273  C CB  . ASP C 1 300 ? 173.069 162.599 174.143 1.00 39.71  ? 321 ASP C CB  1 
ATOM   9274  C CG  . ASP C 1 300 ? 171.576 162.467 174.368 1.00 39.71  ? 321 ASP C CG  1 
ATOM   9275  O OD1 . ASP C 1 300 ? 171.055 161.339 174.253 1.00 39.71  ? 321 ASP C OD1 1 
ATOM   9276  O OD2 . ASP C 1 300 ? 170.925 163.492 174.660 1.00 39.71  ? 321 ASP C OD2 1 
ATOM   9277  N N   . SER C 1 301 ? 175.081 161.284 176.608 1.00 43.41  ? 322 SER C N   1 
ATOM   9278  C CA  . SER C 1 301 ? 175.270 161.136 178.051 1.00 43.41  ? 322 SER C CA  1 
ATOM   9279  C C   . SER C 1 301 ? 175.252 162.502 178.736 1.00 43.41  ? 322 SER C C   1 
ATOM   9280  O O   . SER C 1 301 ? 176.191 162.902 179.424 1.00 43.41  ? 322 SER C O   1 
ATOM   9281  C CB  . SER C 1 301 ? 176.568 160.387 178.337 1.00 43.41  ? 322 SER C CB  1 
ATOM   9282  O OG  . SER C 1 301 ? 177.697 161.178 178.012 1.00 43.41  ? 322 SER C OG  1 
ATOM   9283  N N   . THR C 1 302 ? 174.151 163.224 178.534 1.00 41.20  ? 323 THR C N   1 
ATOM   9284  C CA  . THR C 1 302 ? 173.965 164.516 179.177 1.00 41.20  ? 323 THR C CA  1 
ATOM   9285  C C   . THR C 1 302 ? 173.174 164.421 180.472 1.00 41.20  ? 323 THR C C   1 
ATOM   9286  O O   . THR C 1 302 ? 173.239 165.342 181.293 1.00 41.20  ? 323 THR C O   1 
ATOM   9287  C CB  . THR C 1 302 ? 173.258 165.487 178.226 1.00 41.20  ? 323 THR C CB  1 
ATOM   9288  O OG1 . THR C 1 302 ? 171.884 165.104 178.086 1.00 41.20  ? 323 THR C OG1 1 
ATOM   9289  C CG2 . THR C 1 302 ? 173.924 165.469 176.861 1.00 41.20  ? 323 THR C CG2 1 
ATOM   9290  N N   . ASN C 1 303 ? 172.432 163.330 180.671 1.00 45.56  ? 324 ASN C N   1 
ATOM   9291  C CA  . ASN C 1 303 ? 171.684 163.107 181.901 1.00 45.56  ? 324 ASN C CA  1 
ATOM   9292  C C   . ASN C 1 303 ? 171.986 161.746 182.512 1.00 45.56  ? 324 ASN C C   1 
ATOM   9293  O O   . ASN C 1 303 ? 171.349 161.369 183.502 1.00 45.56  ? 324 ASN C O   1 
ATOM   9294  C CB  . ASN C 1 303 ? 170.178 163.239 181.648 1.00 45.56  ? 324 ASN C CB  1 
ATOM   9295  C CG  . ASN C 1 303 ? 169.803 164.583 181.059 1.00 45.56  ? 324 ASN C CG  1 
ATOM   9296  O OD1 . ASN C 1 303 ? 169.299 164.664 179.939 1.00 45.56  ? 324 ASN C OD1 1 
ATOM   9297  N ND2 . ASN C 1 303 ? 170.049 165.648 181.812 1.00 45.56  ? 324 ASN C ND2 1 
ATOM   9298  N N   . CYS C 1 304 ? 172.937 161.004 181.954 1.00 38.88  ? 325 CYS C N   1 
ATOM   9299  C CA  . CYS C 1 304 ? 173.252 159.653 182.393 1.00 38.88  ? 325 CYS C CA  1 
ATOM   9300  C C   . CYS C 1 304 ? 174.597 159.645 183.101 1.00 38.88  ? 325 CYS C C   1 
ATOM   9301  O O   . CYS C 1 304 ? 175.587 160.157 182.568 1.00 38.88  ? 325 CYS C O   1 
ATOM   9302  C CB  . CYS C 1 304 ? 173.283 158.691 181.205 1.00 38.88  ? 325 CYS C CB  1 
ATOM   9303  S SG  . CYS C 1 304 ? 171.771 158.666 180.227 1.00 38.88  ? 325 CYS C SG  1 
ATOM   9304  N N   . ILE C 1 305 ? 174.630 159.067 184.294 1.00 35.66  ? 326 ILE C N   1 
ATOM   9305  C CA  . ILE C 1 305 ? 175.884 158.892 185.015 1.00 35.66  ? 326 ILE C CA  1 
ATOM   9306  C C   . ILE C 1 305 ? 176.653 157.733 184.398 1.00 35.66  ? 326 ILE C C   1 
ATOM   9307  O O   . ILE C 1 305 ? 176.065 156.795 183.846 1.00 35.66  ? 326 ILE C O   1 
ATOM   9308  C CB  . ILE C 1 305 ? 175.624 158.678 186.518 1.00 35.66  ? 326 ILE C CB  1 
ATOM   9309  C CG1 . ILE C 1 305 ? 174.761 157.438 186.762 1.00 35.66  ? 326 ILE C CG1 1 
ATOM   9310  C CG2 . ILE C 1 305 ? 174.969 159.907 187.126 1.00 35.66  ? 326 ILE C CG2 1 
ATOM   9311  C CD1 . ILE C 1 305 ? 174.652 157.052 188.218 1.00 35.66  ? 326 ILE C CD1 1 
ATOM   9312  N N   . ILE C 1 306 ? 177.978 157.815 184.449 1.00 30.37  ? 327 ILE C N   1 
ATOM   9313  C CA  . ILE C 1 306 ? 178.851 156.788 183.895 1.00 30.37  ? 327 ILE C CA  1 
ATOM   9314  C C   . ILE C 1 306 ? 179.550 156.085 185.047 1.00 30.37  ? 327 ILE C C   1 
ATOM   9315  O O   . ILE C 1 306 ? 180.347 156.697 185.768 1.00 30.37  ? 327 ILE C O   1 
ATOM   9316  C CB  . ILE C 1 306 ? 179.869 157.383 182.911 1.00 30.37  ? 327 ILE C CB  1 
ATOM   9317  C CG1 . ILE C 1 306 ? 179.148 158.077 181.754 1.00 30.37  ? 327 ILE C CG1 1 
ATOM   9318  C CG2 . ILE C 1 306 ? 180.801 156.302 182.392 1.00 30.37  ? 327 ILE C CG2 1 
ATOM   9319  C CD1 . ILE C 1 306 ? 180.066 158.875 180.858 1.00 30.37  ? 327 ILE C CD1 1 
ATOM   9320  N N   . THR C 1 307 ? 179.257 154.802 185.220 1.00 33.41  ? 328 THR C N   1 
ATOM   9321  C CA  . THR C 1 307 ? 179.908 153.997 186.239 1.00 33.41  ? 328 THR C CA  1 
ATOM   9322  C C   . THR C 1 307 ? 181.175 153.376 185.653 1.00 33.41  ? 328 THR C C   1 
ATOM   9323  O O   . THR C 1 307 ? 181.564 153.660 184.517 1.00 33.41  ? 328 THR C O   1 
ATOM   9324  C CB  . THR C 1 307 ? 178.946 152.941 186.777 1.00 33.41  ? 328 THR C CB  1 
ATOM   9325  O OG1 . THR C 1 307 ? 178.833 151.870 185.832 1.00 33.41  ? 328 THR C OG1 1 
ATOM   9326  C CG2 . THR C 1 307 ? 177.573 153.549 187.018 1.00 33.41  ? 328 THR C CG2 1 
ATOM   9327  N N   . ASP C 1 308 ? 181.837 152.519 186.430 1.00 39.62  ? 329 ASP C N   1 
ATOM   9328  C CA  . ASP C 1 308 ? 183.073 151.900 185.969 1.00 39.62  ? 329 ASP C CA  1 
ATOM   9329  C C   . ASP C 1 308 ? 182.824 150.806 184.939 1.00 39.62  ? 329 ASP C C   1 
ATOM   9330  O O   . ASP C 1 308 ? 183.686 150.557 184.089 1.00 39.62  ? 329 ASP C O   1 
ATOM   9331  C CB  . ASP C 1 308 ? 183.851 151.332 187.156 1.00 39.62  ? 329 ASP C CB  1 
ATOM   9332  C CG  . ASP C 1 308 ? 182.984 150.489 188.070 1.00 39.62  ? 329 ASP C CG  1 
ATOM   9333  O OD1 . ASP C 1 308 ? 181.748 150.493 187.892 1.00 39.62  ? 329 ASP C OD1 1 
ATOM   9334  O OD2 . ASP C 1 308 ? 183.540 149.822 188.967 1.00 39.62  ? 329 ASP C OD2 1 
ATOM   9335  N N   . ASN C 1 309 ? 181.665 150.148 184.993 1.00 37.90  ? 330 ASN C N   1 
ATOM   9336  C CA  . ASN C 1 309 ? 181.381 149.020 184.119 1.00 37.90  ? 330 ASN C CA  1 
ATOM   9337  C C   . ASN C 1 309 ? 180.173 149.201 183.212 1.00 37.90  ? 330 ASN C C   1 
ATOM   9338  O O   . ASN C 1 309 ? 180.024 148.423 182.263 1.00 37.90  ? 330 ASN C O   1 
ATOM   9339  C CB  . ASN C 1 309 ? 181.185 147.738 184.945 1.00 37.90  ? 330 ASN C CB  1 
ATOM   9340  C CG  . ASN C 1 309 ? 180.172 147.907 186.069 1.00 37.90  ? 330 ASN C CG  1 
ATOM   9341  O OD1 . ASN C 1 309 ? 179.558 148.963 186.225 1.00 37.90  ? 330 ASN C OD1 1 
ATOM   9342  N ND2 . ASN C 1 309 ? 179.995 146.856 186.860 1.00 37.90  ? 330 ASN C ND2 1 
ATOM   9343  N N   . SER C 1 310 ? 179.313 150.186 183.464 1.00 29.74  ? 331 SER C N   1 
ATOM   9344  C CA  . SER C 1 310 ? 178.075 150.301 182.708 1.00 29.74  ? 331 SER C CA  1 
ATOM   9345  C C   . SER C 1 310 ? 177.590 151.742 182.703 1.00 29.74  ? 331 SER C C   1 
ATOM   9346  O O   . SER C 1 310 ? 178.029 152.573 183.501 1.00 29.74  ? 331 SER C O   1 
ATOM   9347  C CB  . SER C 1 310 ? 176.985 149.390 183.280 1.00 29.74  ? 331 SER C CB  1 
ATOM   9348  O OG  . SER C 1 310 ? 175.743 149.631 182.642 1.00 29.74  ? 331 SER C OG  1 
ATOM   9349  N N   . TYR C 1 311 ? 176.674 152.021 181.781 1.00 27.46  ? 332 TYR C N   1 
ATOM   9350  C CA  . TYR C 1 311 ? 175.981 153.299 181.706 1.00 27.46  ? 332 TYR C CA  1 
ATOM   9351  C C   . TYR C 1 311 ? 174.626 153.167 182.385 1.00 27.46  ? 332 TYR C C   1 
ATOM   9352  O O   . TYR C 1 311 ? 173.889 152.210 182.126 1.00 27.46  ? 332 TYR C O   1 
ATOM   9353  C CB  . TYR C 1 311 ? 175.789 153.738 180.253 1.00 27.46  ? 332 TYR C CB  1 
ATOM   9354  C CG  . TYR C 1 311 ? 176.938 154.524 179.670 1.00 27.46  ? 332 TYR C CG  1 
ATOM   9355  C CD1 . TYR C 1 311 ? 178.201 153.960 179.547 1.00 27.46  ? 332 TYR C CD1 1 
ATOM   9356  C CD2 . TYR C 1 311 ? 176.756 155.830 179.232 1.00 27.46  ? 332 TYR C CD2 1 
ATOM   9357  C CE1 . TYR C 1 311 ? 179.254 154.677 179.008 1.00 27.46  ? 332 TYR C CE1 1 
ATOM   9358  C CE2 . TYR C 1 311 ? 177.802 156.556 178.693 1.00 27.46  ? 332 TYR C CE2 1 
ATOM   9359  C CZ  . TYR C 1 311 ? 179.048 155.973 178.584 1.00 27.46  ? 332 TYR C CZ  1 
ATOM   9360  O OH  . TYR C 1 311 ? 180.093 156.689 178.049 1.00 27.46  ? 332 TYR C OH  1 
ATOM   9361  N N   . VAL C 1 312 ? 174.298 154.123 183.247 1.00 29.58  ? 333 VAL C N   1 
ATOM   9362  C CA  . VAL C 1 312 ? 173.004 154.170 183.916 1.00 29.58  ? 333 VAL C CA  1 
ATOM   9363  C C   . VAL C 1 312 ? 172.275 155.410 183.427 1.00 29.58  ? 333 VAL C C   1 
ATOM   9364  O O   . VAL C 1 312 ? 172.719 156.537 183.680 1.00 29.58  ? 333 VAL C O   1 
ATOM   9365  C CB  . VAL C 1 312 ? 173.145 154.184 185.445 1.00 29.58  ? 333 VAL C CB  1 
ATOM   9366  C CG1 . VAL C 1 312 ? 171.778 154.283 186.098 1.00 29.58  ? 333 VAL C CG1 1 
ATOM   9367  C CG2 . VAL C 1 312 ? 173.873 152.941 185.918 1.00 29.58  ? 333 VAL C CG2 1 
ATOM   9368  N N   . CYS C 1 313 ? 171.157 155.206 182.738 1.00 35.04  ? 334 CYS C N   1 
ATOM   9369  C CA  . CYS C 1 313 ? 170.353 156.292 182.204 1.00 35.04  ? 334 CYS C CA  1 
ATOM   9370  C C   . CYS C 1 313 ? 168.997 156.326 182.892 1.00 35.04  ? 334 CYS C C   1 
ATOM   9371  O O   . CYS C 1 313 ? 168.438 155.286 183.252 1.00 35.04  ? 334 CYS C O   1 
ATOM   9372  C CB  . CYS C 1 313 ? 170.158 156.157 180.689 1.00 35.04  ? 334 CYS C CB  1 
ATOM   9373  S SG  . CYS C 1 313 ? 171.561 156.716 179.707 1.00 35.04  ? 334 CYS C SG  1 
ATOM   9374  N N   . ASP C 1 314 ? 168.484 157.544 183.081 1.00 49.88  ? 335 ASP C N   1 
ATOM   9375  C CA  . ASP C 1 314 ? 167.146 157.722 183.632 1.00 49.88  ? 335 ASP C CA  1 
ATOM   9376  C C   . ASP C 1 314 ? 166.078 157.219 182.670 1.00 49.88  ? 335 ASP C C   1 
ATOM   9377  O O   . ASP C 1 314 ? 165.037 156.714 183.104 1.00 49.88  ? 335 ASP C O   1 
ATOM   9378  C CB  . ASP C 1 314 ? 166.914 159.198 183.957 1.00 49.88  ? 335 ASP C CB  1 
ATOM   9379  C CG  . ASP C 1 314 ? 165.767 159.416 184.925 1.00 49.88  ? 335 ASP C CG  1 
ATOM   9380  O OD1 . ASP C 1 314 ? 165.231 158.424 185.459 1.00 49.88  ? 335 ASP C OD1 1 
ATOM   9381  O OD2 . ASP C 1 314 ? 165.399 160.588 185.150 1.00 49.88  ? 335 ASP C OD2 1 
ATOM   9382  N N   . ARG C 1 315 ? 166.327 157.336 181.369 1.00 51.50  ? 336 ARG C N   1 
ATOM   9383  C CA  . ARG C 1 315 ? 165.357 156.976 180.348 1.00 51.50  ? 336 ARG C CA  1 
ATOM   9384  C C   . ARG C 1 315 ? 166.139 156.698 179.070 1.00 51.50  ? 336 ARG C C   1 
ATOM   9385  O O   . ARG C 1 315 ? 167.304 157.086 178.950 1.00 51.50  ? 336 ARG C O   1 
ATOM   9386  C CB  . ARG C 1 315 ? 164.322 158.097 180.179 1.00 51.50  ? 336 ARG C CB  1 
ATOM   9387  C CG  . ARG C 1 315 ? 163.035 157.736 179.463 1.00 51.50  ? 336 ARG C CG  1 
ATOM   9388  C CD  . ARG C 1 315 ? 163.021 158.342 178.076 1.00 51.50  ? 336 ARG C CD  1 
ATOM   9389  N NE  . ARG C 1 315 ? 163.529 159.710 178.077 1.00 51.50  ? 336 ARG C NE  1 
ATOM   9390  C CZ  . ARG C 1 315 ? 162.822 160.780 178.416 1.00 51.50  ? 336 ARG C CZ  1 
ATOM   9391  N NH1 . ARG C 1 315 ? 161.552 160.686 178.776 1.00 51.50  ? 336 ARG C NH1 1 
ATOM   9392  N NH2 . ARG C 1 315 ? 163.402 161.976 178.388 1.00 51.50  ? 336 ARG C NH2 1 
ATOM   9393  N N   . ASP C 1 316 ? 165.501 155.989 178.136 1.00 42.43  ? 337 ASP C N   1 
ATOM   9394  C CA  . ASP C 1 316 ? 166.147 155.620 176.882 1.00 42.43  ? 337 ASP C CA  1 
ATOM   9395  C C   . ASP C 1 316 ? 166.444 156.855 176.038 1.00 42.43  ? 337 ASP C C   1 
ATOM   9396  O O   . ASP C 1 316 ? 165.583 157.721 175.860 1.00 42.43  ? 337 ASP C O   1 
ATOM   9397  C CB  . ASP C 1 316 ? 165.262 154.650 176.100 1.00 42.43  ? 337 ASP C CB  1 
ATOM   9398  C CG  . ASP C 1 316 ? 166.055 153.775 175.151 1.00 42.43  ? 337 ASP C CG  1 
ATOM   9399  O OD1 . ASP C 1 316 ? 167.293 153.928 175.091 1.00 42.43  ? 337 ASP C OD1 1 
ATOM   9400  O OD2 . ASP C 1 316 ? 165.439 152.934 174.463 1.00 42.43  ? 337 ASP C OD2 1 
ATOM   9401  N N   . TYR C 1 317 ? 167.668 156.931 175.524 1.00 41.76  ? 338 TYR C N   1 
ATOM   9402  C CA  . TYR C 1 317 ? 168.157 158.076 174.761 1.00 41.76  ? 338 TYR C CA  1 
ATOM   9403  C C   . TYR C 1 317 ? 168.747 157.619 173.435 1.00 41.76  ? 338 TYR C C   1 
ATOM   9404  O O   . TYR C 1 317 ? 169.832 158.040 173.029 1.00 41.76  ? 338 TYR C O   1 
ATOM   9405  C CB  . TYR C 1 317 ? 169.199 158.860 175.554 1.00 41.76  ? 338 TYR C CB  1 
ATOM   9406  C CG  . TYR C 1 317 ? 168.637 159.702 176.675 1.00 41.76  ? 338 TYR C CG  1 
ATOM   9407  C CD1 . TYR C 1 317 ? 167.407 160.335 176.547 1.00 41.76  ? 338 TYR C CD1 1 
ATOM   9408  C CD2 . TYR C 1 317 ? 169.345 159.873 177.859 1.00 41.76  ? 338 TYR C CD2 1 
ATOM   9409  C CE1 . TYR C 1 317 ? 166.893 161.111 177.572 1.00 41.76  ? 338 TYR C CE1 1 
ATOM   9410  C CE2 . TYR C 1 317 ? 168.841 160.646 178.889 1.00 41.76  ? 338 TYR C CE2 1 
ATOM   9411  C CZ  . TYR C 1 317 ? 167.615 161.262 178.739 1.00 41.76  ? 338 TYR C CZ  1 
ATOM   9412  O OH  . TYR C 1 317 ? 167.109 162.032 179.761 1.00 41.76  ? 338 TYR C OH  1 
ATOM   9413  N N   . SER C 1 318 ? 168.034 156.741 172.737 1.00 50.75  ? 339 SER C N   1 
ATOM   9414  C CA  . SER C 1 318 ? 168.502 156.197 171.466 1.00 50.75  ? 339 SER C CA  1 
ATOM   9415  C C   . SER C 1 318 ? 168.111 157.154 170.344 1.00 50.75  ? 339 SER C C   1 
ATOM   9416  O O   . SER C 1 318 ? 166.924 157.328 170.052 1.00 50.75  ? 339 SER C O   1 
ATOM   9417  C CB  . SER C 1 318 ? 167.923 154.805 171.232 1.00 50.75  ? 339 SER C CB  1 
ATOM   9418  O OG  . SER C 1 318 ? 168.384 154.261 170.008 1.00 50.75  ? 339 SER C OG  1 
ATOM   9419  N N   . LEU C 1 319 ? 169.121 157.777 169.710 1.00 53.47  ? 340 LEU C N   1 
ATOM   9420  C CA  . LEU C 1 319 ? 169.001 158.695 168.587 1.00 53.47  ? 340 LEU C CA  1 
ATOM   9421  C C   . LEU C 1 319 ? 169.428 158.012 167.291 1.00 53.47  ? 340 LEU C C   1 
ATOM   9422  O O   . LEU C 1 319 ? 170.317 157.155 167.300 1.00 53.47  ? 340 LEU C O   1 
ATOM   9423  C CB  . LEU C 1 319 ? 169.859 159.951 168.806 1.00 53.47  ? 340 LEU C CB  1 
ATOM   9424  C CG  . LEU C 1 319 ? 169.358 161.102 169.690 1.00 53.47  ? 340 LEU C CG  1 
ATOM   9425  C CD1 . LEU C 1 319 ? 169.400 160.787 171.179 1.00 53.47  ? 340 LEU C CD1 1 
ATOM   9426  C CD2 . LEU C 1 319 ? 170.144 162.370 169.390 1.00 53.47  ? 340 LEU C CD2 1 
ATOM   9427  N N   . PRO C 1 320 ? 168.819 158.351 166.156 1.00 64.25  ? 341 PRO C N   1 
ATOM   9428  C CA  . PRO C 1 320 ? 169.228 157.746 164.885 1.00 64.25  ? 341 PRO C CA  1 
ATOM   9429  C C   . PRO C 1 320 ? 170.541 158.334 164.382 1.00 64.25  ? 341 PRO C C   1 
ATOM   9430  O O   . PRO C 1 320 ? 171.048 159.335 164.888 1.00 64.25  ? 341 PRO C O   1 
ATOM   9431  C CB  . PRO C 1 320 ? 168.071 158.093 163.946 1.00 64.25  ? 341 PRO C CB  1 
ATOM   9432  C CG  . PRO C 1 320 ? 167.542 159.367 164.488 1.00 64.25  ? 341 PRO C CG  1 
ATOM   9433  C CD  . PRO C 1 320 ? 167.661 159.247 165.982 1.00 64.25  ? 341 PRO C CD  1 
ATOM   9434  N N   . MET C 1 321 ? 171.089 157.682 163.358 1.00 81.85  ? 342 MET C N   1 
ATOM   9435  C CA  . MET C 1 321 ? 172.359 158.079 162.771 1.00 81.85  ? 342 MET C CA  1 
ATOM   9436  C C   . MET C 1 321 ? 172.268 158.039 161.251 1.00 81.85  ? 342 MET C C   1 
ATOM   9437  O O   . MET C 1 321 ? 171.403 157.376 160.673 1.00 81.85  ? 342 MET C O   1 
ATOM   9438  C CB  . MET C 1 321 ? 173.505 157.180 163.248 1.00 81.85  ? 342 MET C CB  1 
ATOM   9439  C CG  . MET C 1 321 ? 173.371 155.733 162.822 1.00 81.85  ? 342 MET C CG  1 
ATOM   9440  S SD  . MET C 1 321 ? 174.722 154.723 163.447 1.00 81.85  ? 342 MET C SD  1 
ATOM   9441  C CE  . MET C 1 321 ? 176.070 155.256 162.402 1.00 81.85  ? 342 MET C CE  1 
ATOM   9442  N N   . ASN C 1 322 ? 173.175 158.774 160.615 1.00 93.57  ? 343 ASN C N   1 
ATOM   9443  C CA  . ASN C 1 322 ? 173.214 158.832 159.162 1.00 93.57  ? 343 ASN C CA  1 
ATOM   9444  C C   . ASN C 1 322 ? 173.758 157.521 158.594 1.00 93.57  ? 343 ASN C C   1 
ATOM   9445  O O   . ASN C 1 322 ? 174.642 156.904 159.198 1.00 93.57  ? 343 ASN C O   1 
ATOM   9446  C CB  . ASN C 1 322 ? 174.087 160.001 158.705 1.00 93.57  ? 343 ASN C CB  1 
ATOM   9447  C CG  . ASN C 1 322 ? 173.783 160.443 157.287 1.00 93.57  ? 343 ASN C CG  1 
ATOM   9448  O OD1 . ASN C 1 322 ? 174.091 159.743 156.328 1.00 93.57  ? 343 ASN C OD1 1 
ATOM   9449  N ND2 . ASN C 1 322 ? 173.191 161.621 157.149 1.00 93.57  ? 343 ASN C ND2 1 
ATOM   9450  N N   . PRO C 1 323 ? 173.229 157.055 157.457 1.00 89.92  ? 344 PRO C N   1 
ATOM   9451  C CA  . PRO C 1 323 ? 173.836 155.894 156.779 1.00 89.92  ? 344 PRO C CA  1 
ATOM   9452  C C   . PRO C 1 323 ? 175.257 156.129 156.283 1.00 89.92  ? 344 PRO C C   1 
ATOM   9453  O O   . PRO C 1 323 ? 176.001 155.153 156.119 1.00 89.92  ? 344 PRO C O   1 
ATOM   9454  C CB  . PRO C 1 323 ? 172.875 155.629 155.614 1.00 89.92  ? 344 PRO C CB  1 
ATOM   9455  C CG  . PRO C 1 323 ? 171.569 156.168 156.084 1.00 89.92  ? 344 PRO C CG  1 
ATOM   9456  C CD  . PRO C 1 323 ? 171.901 157.380 156.905 1.00 89.92  ? 344 PRO C CD  1 
ATOM   9457  N N   . ILE C 1 324 ? 175.649 157.382 156.027 1.00 88.23  ? 345 ILE C N   1 
ATOM   9458  C CA  . ILE C 1 324 ? 177.036 157.678 155.674 1.00 88.23  ? 345 ILE C CA  1 
ATOM   9459  C C   . ILE C 1 324 ? 177.956 157.398 156.859 1.00 88.23  ? 345 ILE C C   1 
ATOM   9460  O O   . ILE C 1 324 ? 179.054 156.854 156.693 1.00 88.23  ? 345 ILE C O   1 
ATOM   9461  C CB  . ILE C 1 324 ? 177.159 159.130 155.169 1.00 88.23  ? 345 ILE C CB  1 
ATOM   9462  C CG1 . ILE C 1 324 ? 176.292 159.335 153.924 1.00 88.23  ? 345 ILE C CG1 1 
ATOM   9463  C CG2 . ILE C 1 324 ? 178.600 159.490 154.839 1.00 88.23  ? 345 ILE C CG2 1 
ATOM   9464  C CD1 . ILE C 1 324 ? 176.642 158.416 152.771 1.00 88.23  ? 345 ILE C CD1 1 
ATOM   9465  N N   . LEU C 1 325 ? 177.505 157.718 158.076 1.00 86.80  ? 346 LEU C N   1 
ATOM   9466  C CA  . LEU C 1 325 ? 178.253 157.335 159.271 1.00 86.80  ? 346 LEU C CA  1 
ATOM   9467  C C   . LEU C 1 325 ? 178.267 155.823 159.475 1.00 86.80  ? 346 LEU C C   1 
ATOM   9468  O O   . LEU C 1 325 ? 179.245 155.284 160.002 1.00 86.80  ? 346 LEU C O   1 
ATOM   9469  C CB  . LEU C 1 325 ? 177.680 158.027 160.510 1.00 86.80  ? 346 LEU C CB  1 
ATOM   9470  C CG  . LEU C 1 325 ? 178.276 159.359 160.981 1.00 86.80  ? 346 LEU C CG  1 
ATOM   9471  C CD1 . LEU C 1 325 ? 179.731 159.173 161.386 1.00 86.80  ? 346 LEU C CD1 1 
ATOM   9472  C CD2 . LEU C 1 325 ? 178.140 160.458 159.943 1.00 86.80  ? 346 LEU C CD2 1 
ATOM   9473  N N   . ARG C 1 326 ? 177.204 155.128 159.055 1.00 92.41  ? 347 ARG C N   1 
ATOM   9474  C CA  . ARG C 1 326 ? 177.189 153.668 159.121 1.00 92.41  ? 347 ARG C CA  1 
ATOM   9475  C C   . ARG C 1 326 ? 178.216 153.057 158.173 1.00 92.41  ? 347 ARG C C   1 
ATOM   9476  O O   . ARG C 1 326 ? 178.920 152.107 158.539 1.00 92.41  ? 347 ARG C O   1 
ATOM   9477  C CB  . ARG C 1 326 ? 175.785 153.150 158.805 1.00 92.41  ? 347 ARG C CB  1 
ATOM   9478  C CG  . ARG C 1 326 ? 175.654 151.636 158.808 1.00 92.41  ? 347 ARG C CG  1 
ATOM   9479  C CD  . ARG C 1 326 ? 174.304 151.203 158.261 1.00 92.41  ? 347 ARG C CD  1 
ATOM   9480  N NE  . ARG C 1 326 ? 173.204 151.927 158.887 1.00 92.41  ? 347 ARG C NE  1 
ATOM   9481  C CZ  . ARG C 1 326 ? 172.646 151.593 160.043 1.00 92.41  ? 347 ARG C CZ  1 
ATOM   9482  N NH1 . ARG C 1 326 ? 173.053 150.536 160.727 1.00 92.41  ? 347 ARG C NH1 1 
ATOM   9483  N NH2 . ARG C 1 326 ? 171.653 152.335 160.522 1.00 92.41  ? 347 ARG C NH2 1 
ATOM   9484  N N   . GLU C 1 327 ? 178.328 153.605 156.958 1.00 92.30  ? 348 GLU C N   1 
ATOM   9485  C CA  . GLU C 1 327 ? 179.367 153.161 156.033 1.00 92.30  ? 348 GLU C CA  1 
ATOM   9486  C C   . GLU C 1 327 ? 180.757 153.551 156.521 1.00 92.30  ? 348 GLU C C   1 
ATOM   9487  O O   . GLU C 1 327 ? 181.725 152.825 156.267 1.00 92.30  ? 348 GLU C O   1 
ATOM   9488  C CB  . GLU C 1 327 ? 179.119 153.739 154.639 1.00 92.30  ? 348 GLU C CB  1 
ATOM   9489  C CG  . GLU C 1 327 ? 177.803 153.318 154.006 1.00 92.30  ? 348 GLU C CG  1 
ATOM   9490  C CD  . GLU C 1 327 ? 177.444 151.876 154.304 1.00 92.30  ? 348 GLU C CD  1 
ATOM   9491  O OE1 . GLU C 1 327 ? 178.120 150.971 153.771 1.00 92.30  ? 348 GLU C OE1 1 
ATOM   9492  O OE2 . GLU C 1 327 ? 176.484 151.647 155.069 1.00 92.30  ? 348 GLU C OE2 1 
ATOM   9493  N N   . CYS C 1 328 ? 180.868 154.693 157.208 1.00 84.93  ? 349 CYS C N   1 
ATOM   9494  C CA  . CYS C 1 328 ? 182.134 155.108 157.803 1.00 84.93  ? 349 CYS C CA  1 
ATOM   9495  C C   . CYS C 1 328 ? 182.580 154.142 158.893 1.00 84.93  ? 349 CYS C C   1 
ATOM   9496  O O   . CYS C 1 328 ? 183.766 153.806 158.991 1.00 84.93  ? 349 CYS C O   1 
ATOM   9497  C CB  . CYS C 1 328 ? 182.000 156.524 158.363 1.00 84.93  ? 349 CYS C CB  1 
ATOM   9498  S SG  . CYS C 1 328 ? 183.326 157.029 159.478 1.00 84.93  ? 349 CYS C SG  1 
ATOM   9499  N N   . PHE C 1 329 ? 181.640 153.681 159.714 1.00 73.51  ? 350 PHE C N   1 
ATOM   9500  C CA  . PHE C 1 329 ? 181.986 152.749 160.777 1.00 73.51  ? 350 PHE C CA  1 
ATOM   9501  C C   . PHE C 1 329 ? 182.217 151.337 160.257 1.00 73.51  ? 350 PHE C C   1 
ATOM   9502  O O   . PHE C 1 329 ? 183.050 150.613 160.812 1.00 73.51  ? 350 PHE C O   1 
ATOM   9503  C CB  . PHE C 1 329 ? 180.894 152.744 161.846 1.00 73.51  ? 350 PHE C CB  1 
ATOM   9504  C CG  . PHE C 1 329 ? 181.142 153.712 162.965 1.00 73.51  ? 350 PHE C CG  1 
ATOM   9505  C CD1 . PHE C 1 329 ? 180.725 155.030 162.862 1.00 73.51  ? 350 PHE C CD1 1 
ATOM   9506  C CD2 . PHE C 1 329 ? 181.800 153.307 164.115 1.00 73.51  ? 350 PHE C CD2 1 
ATOM   9507  C CE1 . PHE C 1 329 ? 180.954 155.928 163.889 1.00 73.51  ? 350 PHE C CE1 1 
ATOM   9508  C CE2 . PHE C 1 329 ? 182.034 154.199 165.146 1.00 73.51  ? 350 PHE C CE2 1 
ATOM   9509  C CZ  . PHE C 1 329 ? 181.610 155.511 165.032 1.00 73.51  ? 350 PHE C CZ  1 
ATOM   9510  N N   . GLU C 1 330 ? 181.514 150.922 159.201 1.00 90.99  ? 351 GLU C N   1 
ATOM   9511  C CA  . GLU C 1 330 ? 181.619 149.527 158.775 1.00 90.99  ? 351 GLU C CA  1 
ATOM   9512  C C   . GLU C 1 330 ? 182.857 149.279 157.915 1.00 90.99  ? 351 GLU C C   1 
ATOM   9513  O O   . GLU C 1 330 ? 183.787 148.583 158.333 1.00 90.99  ? 351 GLU C O   1 
ATOM   9514  C CB  . GLU C 1 330 ? 180.351 149.116 158.019 1.00 90.99  ? 351 GLU C CB  1 
ATOM   9515  C CG  . GLU C 1 330 ? 179.205 148.664 158.906 1.00 90.99  ? 351 GLU C CG  1 
ATOM   9516  C CD  . GLU C 1 330 ? 177.856 148.813 158.230 1.00 90.99  ? 351 GLU C CD  1 
ATOM   9517  O OE1 . GLU C 1 330 ? 177.791 149.474 157.171 1.00 90.99  ? 351 GLU C OE1 1 
ATOM   9518  O OE2 . GLU C 1 330 ? 176.862 148.268 158.753 1.00 90.99  ? 351 GLU C OE2 1 
ATOM   9519  N N   . GLY C 1 331 ? 182.887 149.843 156.708 1.00 92.44  ? 352 GLY C N   1 
ATOM   9520  C CA  . GLY C 1 331 ? 183.997 149.582 155.810 1.00 92.44  ? 352 GLY C CA  1 
ATOM   9521  C C   . GLY C 1 331 ? 184.681 150.773 155.170 1.00 92.44  ? 352 GLY C C   1 
ATOM   9522  O O   . GLY C 1 331 ? 185.861 150.697 154.814 1.00 92.44  ? 352 GLY C O   1 
ATOM   9523  N N   . ASN C 1 332 ? 183.959 151.880 155.019 1.00 98.47  ? 353 ASN C N   1 
ATOM   9524  C CA  . ASN C 1 332 ? 184.345 152.952 154.101 1.00 98.47  ? 353 ASN C CA  1 
ATOM   9525  C C   . ASN C 1 332 ? 185.035 154.063 154.880 1.00 98.47  ? 353 ASN C C   1 
ATOM   9526  O O   . ASN C 1 332 ? 184.379 154.965 155.404 1.00 98.47  ? 353 ASN C O   1 
ATOM   9527  C CB  . ASN C 1 332 ? 183.122 153.489 153.365 1.00 98.47  ? 353 ASN C CB  1 
ATOM   9528  C CG  . ASN C 1 332 ? 182.503 152.472 152.424 1.00 98.47  ? 353 ASN C CG  1 
ATOM   9529  O OD1 . ASN C 1 332 ? 181.366 152.643 151.983 1.00 98.47  ? 353 ASN C OD1 1 
ATOM   9530  N ND2 . ASN C 1 332 ? 183.253 151.424 152.090 1.00 98.47  ? 353 ASN C ND2 1 
ATOM   9531  N N   . THR C 1 333 ? 186.366 154.026 154.927 1.00 87.52  ? 354 THR C N   1 
ATOM   9532  C CA  . THR C 1 333 ? 187.107 155.125 155.534 1.00 87.52  ? 354 THR C CA  1 
ATOM   9533  C C   . THR C 1 333 ? 187.138 156.372 154.660 1.00 87.52  ? 354 THR C C   1 
ATOM   9534  O O   . THR C 1 333 ? 187.503 157.444 155.153 1.00 87.52  ? 354 THR C O   1 
ATOM   9535  C CB  . THR C 1 333 ? 188.536 154.690 155.864 1.00 87.52  ? 354 THR C CB  1 
ATOM   9536  O OG1 . THR C 1 333 ? 189.174 154.195 154.683 1.00 87.52  ? 354 THR C OG1 1 
ATOM   9537  C CG2 . THR C 1 333 ? 188.527 153.611 156.926 1.00 87.52  ? 354 THR C CG2 1 
ATOM   9538  N N   . SER C 1 334 ? 186.759 156.268 153.385 1.00 86.01  ? 355 SER C N   1 
ATOM   9539  C CA  . SER C 1 334 ? 186.586 157.453 152.557 1.00 86.01  ? 355 SER C CA  1 
ATOM   9540  C C   . SER C 1 334 ? 185.330 158.236 152.916 1.00 86.01  ? 355 SER C C   1 
ATOM   9541  O O   . SER C 1 334 ? 185.219 159.407 152.541 1.00 86.01  ? 355 SER C O   1 
ATOM   9542  C CB  . SER C 1 334 ? 186.545 157.063 151.079 1.00 86.01  ? 355 SER C CB  1 
ATOM   9543  O OG  . SER C 1 334 ? 185.298 156.482 150.741 1.00 86.01  ? 355 SER C OG  1 
ATOM   9544  N N   . SER C 1 335 ? 184.386 157.619 153.625 1.00 86.65  ? 356 SER C N   1 
ATOM   9545  C CA  . SER C 1 335 ? 183.174 158.289 154.075 1.00 86.65  ? 356 SER C CA  1 
ATOM   9546  C C   . SER C 1 335 ? 183.330 158.941 155.442 1.00 86.65  ? 356 SER C C   1 
ATOM   9547  O O   . SER C 1 335 ? 182.370 159.536 155.942 1.00 86.65  ? 356 SER C O   1 
ATOM   9548  C CB  . SER C 1 335 ? 182.006 157.299 154.109 1.00 86.65  ? 356 SER C CB  1 
ATOM   9549  O OG  . SER C 1 335 ? 181.707 156.817 152.810 1.00 86.65  ? 356 SER C OG  1 
ATOM   9550  N N   . CYS C 1 336 ? 184.502 158.839 156.060 1.00 82.67  ? 357 CYS C N   1 
ATOM   9551  C CA  . CYS C 1 336 ? 184.765 159.457 157.351 1.00 82.67  ? 357 CYS C CA  1 
ATOM   9552  C C   . CYS C 1 336 ? 185.475 160.787 157.147 1.00 82.67  ? 357 CYS C C   1 
ATOM   9553  O O   . CYS C 1 336 ? 186.453 160.873 156.399 1.00 82.67  ? 357 CYS C O   1 
ATOM   9554  C CB  . CYS C 1 336 ? 185.616 158.544 158.233 1.00 82.67  ? 357 CYS C CB  1 
ATOM   9555  S SG  . CYS C 1 336 ? 185.009 156.853 158.360 1.00 82.67  ? 357 CYS C SG  1 
ATOM   9556  N N   . GLY C 1 337 ? 184.980 161.823 157.819 1.00 71.87  ? 358 GLY C N   1 
ATOM   9557  C CA  . GLY C 1 337 ? 185.544 163.146 157.683 1.00 71.87  ? 358 GLY C CA  1 
ATOM   9558  C C   . GLY C 1 337 ? 186.803 163.337 158.506 1.00 71.87  ? 358 GLY C C   1 
ATOM   9559  O O   . GLY C 1 337 ? 187.294 162.433 159.180 1.00 71.87  ? 358 GLY C O   1 
ATOM   9560  N N   . ARG C 1 338 ? 187.336 164.555 158.436 1.00 72.90  ? 359 ARG C N   1 
ATOM   9561  C CA  . ARG C 1 338 ? 188.518 164.926 159.199 1.00 72.90  ? 359 ARG C CA  1 
ATOM   9562  C C   . ARG C 1 338 ? 188.477 166.419 159.489 1.00 72.90  ? 359 ARG C C   1 
ATOM   9563  O O   . ARG C 1 338 ? 187.954 167.207 158.698 1.00 72.90  ? 359 ARG C O   1 
ATOM   9564  C CB  . ARG C 1 338 ? 189.809 164.564 158.455 1.00 72.90  ? 359 ARG C CB  1 
ATOM   9565  C CG  . ARG C 1 338 ? 189.890 165.135 157.051 1.00 72.90  ? 359 ARG C CG  1 
ATOM   9566  C CD  . ARG C 1 338 ? 191.285 165.032 156.469 1.00 72.90  ? 359 ARG C CD  1 
ATOM   9567  N NE  . ARG C 1 338 ? 191.335 165.564 155.112 1.00 72.90  ? 359 ARG C NE  1 
ATOM   9568  C CZ  . ARG C 1 338 ? 192.452 165.876 154.471 1.00 72.90  ? 359 ARG C CZ  1 
ATOM   9569  N NH1 . ARG C 1 338 ? 193.636 165.753 155.046 1.00 72.90  ? 359 ARG C NH1 1 
ATOM   9570  N NH2 . ARG C 1 338 ? 192.378 166.331 153.223 1.00 72.90  ? 359 ARG C NH2 1 
ATOM   9571  N N   . GLU C 1 339 ? 189.038 166.801 160.632 1.00 82.05  ? 360 GLU C N   1 
ATOM   9572  C CA  . GLU C 1 339 ? 189.079 168.197 161.036 1.00 82.05  ? 360 GLU C CA  1 
ATOM   9573  C C   . GLU C 1 339 ? 190.500 168.582 161.425 1.00 82.05  ? 360 GLU C C   1 
ATOM   9574  O O   . GLU C 1 339 ? 191.304 167.740 161.842 1.00 82.05  ? 360 GLU C O   1 
ATOM   9575  C CB  . GLU C 1 339 ? 188.090 168.487 162.184 1.00 82.05  ? 360 GLU C CB  1 
ATOM   9576  C CG  . GLU C 1 339 ? 188.550 168.073 163.568 1.00 82.05  ? 360 GLU C CG  1 
ATOM   9577  C CD  . GLU C 1 339 ? 187.423 168.082 164.582 1.00 82.05  ? 360 GLU C CD  1 
ATOM   9578  O OE1 . GLU C 1 339 ? 186.254 168.237 164.171 1.00 82.05  ? 360 GLU C OE1 1 
ATOM   9579  O OE2 . GLU C 1 339 ? 187.706 167.937 165.789 1.00 82.05  ? 360 GLU C OE2 1 
ATOM   9580  N N   . MET C 1 340 ? 190.788 169.873 161.270 1.00 79.91  ? 361 MET C N   1 
ATOM   9581  C CA  . MET C 1 340 ? 192.133 170.431 161.343 1.00 79.91  ? 361 MET C CA  1 
ATOM   9582  C C   . MET C 1 340 ? 192.341 171.165 162.659 1.00 79.91  ? 361 MET C C   1 
ATOM   9583  O O   . MET C 1 340 ? 191.503 171.981 163.056 1.00 79.91  ? 361 MET C O   1 
ATOM   9584  C CB  . MET C 1 340 ? 192.363 171.395 160.178 1.00 79.91  ? 361 MET C CB  1 
ATOM   9585  C CG  . MET C 1 340 ? 193.749 172.008 160.114 1.00 79.91  ? 361 MET C CG  1 
ATOM   9586  S SD  . MET C 1 340 ? 193.949 173.063 158.665 1.00 79.91  ? 361 MET C SD  1 
ATOM   9587  C CE  . MET C 1 340 ? 195.594 173.719 158.932 1.00 79.91  ? 361 MET C CE  1 
ATOM   9588  N N   . VAL C 1 341 ? 193.456 170.874 163.336 1.00 78.11  ? 362 VAL C N   1 
ATOM   9589  C CA  . VAL C 1 341 ? 193.851 171.604 164.534 1.00 78.11  ? 362 VAL C CA  1 
ATOM   9590  C C   . VAL C 1 341 ? 195.338 171.923 164.474 1.00 78.11  ? 362 VAL C C   1 
ATOM   9591  O O   . VAL C 1 341 ? 196.102 171.322 163.716 1.00 78.11  ? 362 VAL C O   1 
ATOM   9592  C CB  . VAL C 1 341 ? 193.548 170.836 165.837 1.00 78.11  ? 362 VAL C CB  1 
ATOM   9593  C CG1 . VAL C 1 341 ? 192.048 170.775 166.121 1.00 78.11  ? 362 VAL C CG1 1 
ATOM   9594  C CG2 . VAL C 1 341 ? 194.173 169.456 165.785 1.00 78.11  ? 362 VAL C CG2 1 
ATOM   9595  N N   . LEU C 1 342 ? 195.739 172.891 165.299 1.00 85.36  ? 363 LEU C N   1 
ATOM   9596  C CA  . LEU C 1 342 ? 197.141 173.222 165.500 1.00 85.36  ? 363 LEU C CA  1 
ATOM   9597  C C   . LEU C 1 342 ? 197.499 173.365 166.973 1.00 85.36  ? 363 LEU C C   1 
ATOM   9598  O O   . LEU C 1 342 ? 198.632 173.747 167.284 1.00 85.36  ? 363 LEU C O   1 
ATOM   9599  C CB  . LEU C 1 342 ? 197.520 174.517 164.755 1.00 85.36  ? 363 LEU C CB  1 
ATOM   9600  C CG  . LEU C 1 342 ? 197.087 175.917 165.221 1.00 85.36  ? 363 LEU C CG  1 
ATOM   9601  C CD1 . LEU C 1 342 ? 197.935 176.969 164.520 1.00 85.36  ? 363 LEU C CD1 1 
ATOM   9602  C CD2 . LEU C 1 342 ? 195.612 176.212 164.978 1.00 85.36  ? 363 LEU C CD2 1 
ATOM   9603  N N   . ASN C 1 343 ? 196.572 173.066 167.881 1.00 97.02  ? 364 ASN C N   1 
ATOM   9604  C CA  . ASN C 1 343 ? 196.801 173.208 169.311 1.00 97.02  ? 364 ASN C CA  1 
ATOM   9605  C C   . ASN C 1 343 ? 197.721 172.099 169.824 1.00 97.02  ? 364 ASN C C   1 
ATOM   9606  O O   . ASN C 1 343 ? 198.001 171.111 169.137 1.00 97.02  ? 364 ASN C O   1 
ATOM   9607  C CB  . ASN C 1 343 ? 195.464 173.213 170.053 1.00 97.02  ? 364 ASN C CB  1 
ATOM   9608  C CG  . ASN C 1 343 ? 194.516 172.135 169.562 1.00 97.02  ? 364 ASN C CG  1 
ATOM   9609  O OD1 . ASN C 1 343 ? 194.909 171.257 168.801 1.00 97.02  ? 364 ASN C OD1 1 
ATOM   9610  N ND2 . ASN C 1 343 ? 193.255 172.221 169.961 1.00 97.02  ? 364 ASN C ND2 1 
ATOM   9611  N N   . SER C 1 344 ? 198.192 172.273 171.057 1.00 99.33  ? 365 SER C N   1 
ATOM   9612  C CA  . SER C 1 344 ? 199.211 171.393 171.615 1.00 99.33  ? 365 SER C CA  1 
ATOM   9613  C C   . SER C 1 344 ? 198.645 170.215 172.393 1.00 99.33  ? 365 SER C C   1 
ATOM   9614  O O   . SER C 1 344 ? 199.376 169.250 172.638 1.00 99.33  ? 365 SER C O   1 
ATOM   9615  C CB  . SER C 1 344 ? 200.147 172.187 172.529 1.00 99.33  ? 365 SER C CB  1 
ATOM   9616  O OG  . SER C 1 344 ? 199.468 172.640 173.684 1.00 99.33  ? 365 SER C OG  1 
ATOM   9617  N N   . TYR C 1 345 ? 197.378 170.265 172.795 1.00 97.46  ? 366 TYR C N   1 
ATOM   9618  C CA  . TYR C 1 345 ? 196.798 169.204 173.624 1.00 97.46  ? 366 TYR C CA  1 
ATOM   9619  C C   . TYR C 1 345 ? 196.107 168.124 172.794 1.00 97.46  ? 366 TYR C C   1 
ATOM   9620  O O   . TYR C 1 345 ? 194.993 167.682 173.082 1.00 97.46  ? 366 TYR C O   1 
ATOM   9621  C CB  . TYR C 1 345 ? 195.851 169.794 174.669 1.00 97.46  ? 366 TYR C CB  1 
ATOM   9622  C CG  . TYR C 1 345 ? 194.602 170.541 174.199 1.00 97.46  ? 366 TYR C CG  1 
ATOM   9623  C CD1 . TYR C 1 345 ? 194.686 171.789 173.587 1.00 97.46  ? 366 TYR C CD1 1 
ATOM   9624  C CD2 . TYR C 1 345 ? 193.328 169.997 174.405 1.00 97.46  ? 366 TYR C CD2 1 
ATOM   9625  C CE1 . TYR C 1 345 ? 193.553 172.465 173.185 1.00 97.46  ? 366 TYR C CE1 1 
ATOM   9626  C CE2 . TYR C 1 345 ? 192.192 170.665 173.990 1.00 97.46  ? 366 TYR C CE2 1 
ATOM   9627  C CZ  . TYR C 1 345 ? 192.310 171.894 173.384 1.00 97.46  ? 366 TYR C CZ  1 
ATOM   9628  O OH  . TYR C 1 345 ? 191.181 172.566 172.981 1.00 97.46  ? 366 TYR C OH  1 
ATOM   9629  N N   . ILE C 1 346 ? 196.808 167.629 171.786 1.00 74.01  ? 367 ILE C N   1 
ATOM   9630  C CA  . ILE C 1 346 ? 196.330 166.529 170.958 1.00 74.01  ? 367 ILE C CA  1 
ATOM   9631  C C   . ILE C 1 346 ? 197.210 165.316 171.236 1.00 74.01  ? 367 ILE C C   1 
ATOM   9632  O O   . ILE C 1 346 ? 198.419 165.369 170.987 1.00 74.01  ? 367 ILE C O   1 
ATOM   9633  C CB  . ILE C 1 346 ? 196.346 166.895 169.472 1.00 74.01  ? 367 ILE C CB  1 
ATOM   9634  C CG1 . ILE C 1 346 ? 195.336 168.006 169.203 1.00 74.01  ? 367 ILE C CG1 1 
ATOM   9635  C CG2 . ILE C 1 346 ? 196.022 165.684 168.633 1.00 74.01  ? 367 ILE C CG2 1 
ATOM   9636  C CD1 . ILE C 1 346 ? 193.903 167.643 169.571 1.00 74.01  ? 367 ILE C CD1 1 
ATOM   9637  N N   . PRO C 1 347 ? 196.664 164.222 171.775 1.00 63.92  ? 368 PRO C N   1 
ATOM   9638  C CA  . PRO C 1 347 ? 197.492 163.031 172.013 1.00 63.92  ? 368 PRO C CA  1 
ATOM   9639  C C   . PRO C 1 347 ? 197.884 162.364 170.702 1.00 63.92  ? 368 PRO C C   1 
ATOM   9640  O O   . PRO C 1 347 ? 197.120 162.345 169.734 1.00 63.92  ? 368 PRO C O   1 
ATOM   9641  C CB  . PRO C 1 347 ? 196.592 162.131 172.862 1.00 63.92  ? 368 PRO C CB  1 
ATOM   9642  C CG  . PRO C 1 347 ? 195.214 162.566 172.539 1.00 63.92  ? 368 PRO C CG  1 
ATOM   9643  C CD  . PRO C 1 347 ? 195.287 164.038 172.259 1.00 63.92  ? 368 PRO C CD  1 
ATOM   9644  N N   . LEU C 1 348 ? 199.095 161.811 170.680 1.00 48.56  ? 369 LEU C N   1 
ATOM   9645  C CA  . LEU C 1 348 ? 199.656 161.224 169.478 1.00 48.56  ? 369 LEU C CA  1 
ATOM   9646  C C   . LEU C 1 348 ? 199.948 159.739 169.616 1.00 48.56  ? 369 LEU C C   1 
ATOM   9647  O O   . LEU C 1 348 ? 200.447 159.130 168.661 1.00 48.56  ? 369 LEU C O   1 
ATOM   9648  C CB  . LEU C 1 348 ? 200.937 161.965 169.073 1.00 48.56  ? 369 LEU C CB  1 
ATOM   9649  C CG  . LEU C 1 348 ? 200.738 163.431 168.682 1.00 48.56  ? 369 LEU C CG  1 
ATOM   9650  C CD1 . LEU C 1 348 ? 201.973 164.252 169.008 1.00 48.56  ? 369 LEU C CD1 1 
ATOM   9651  C CD2 . LEU C 1 348 ? 200.379 163.565 167.212 1.00 48.56  ? 369 LEU C CD2 1 
ATOM   9652  N N   . TYR C 1 349 ? 199.659 159.139 170.766 1.00 44.34  ? 370 TYR C N   1 
ATOM   9653  C CA  . TYR C 1 349 ? 199.882 157.718 170.976 1.00 44.34  ? 370 TYR C CA  1 
ATOM   9654  C C   . TYR C 1 349 ? 198.900 157.216 172.019 1.00 44.34  ? 370 TYR C C   1 
ATOM   9655  O O   . TYR C 1 349 ? 198.477 157.964 172.904 1.00 44.34  ? 370 TYR C O   1 
ATOM   9656  C CB  . TYR C 1 349 ? 201.323 157.424 171.416 1.00 44.34  ? 370 TYR C CB  1 
ATOM   9657  C CG  . TYR C 1 349 ? 201.631 157.757 172.860 1.00 44.34  ? 370 TYR C CG  1 
ATOM   9658  C CD1 . TYR C 1 349 ? 201.816 159.074 173.262 1.00 44.34  ? 370 TYR C CD1 1 
ATOM   9659  C CD2 . TYR C 1 349 ? 201.753 156.753 173.817 1.00 44.34  ? 370 TYR C CD2 1 
ATOM   9660  C CE1 . TYR C 1 349 ? 202.102 159.385 174.577 1.00 44.34  ? 370 TYR C CE1 1 
ATOM   9661  C CE2 . TYR C 1 349 ? 202.036 157.055 175.135 1.00 44.34  ? 370 TYR C CE2 1 
ATOM   9662  C CZ  . TYR C 1 349 ? 202.210 158.372 175.507 1.00 44.34  ? 370 TYR C CZ  1 
ATOM   9663  O OH  . TYR C 1 349 ? 202.494 158.675 176.817 1.00 44.34  ? 370 TYR C OH  1 
ATOM   9664  N N   . ALA C 1 350 ? 198.549 155.938 171.908 1.00 40.80  ? 371 ALA C N   1 
ATOM   9665  C CA  . ALA C 1 350 ? 197.682 155.299 172.889 1.00 40.80  ? 371 ALA C CA  1 
ATOM   9666  C C   . ALA C 1 350 ? 197.966 153.801 172.902 1.00 40.80  ? 371 ALA C C   1 
ATOM   9667  O O   . ALA C 1 350 ? 198.674 153.270 172.037 1.00 40.80  ? 371 ALA C O   1 
ATOM   9668  C CB  . ALA C 1 350 ? 196.205 155.599 172.605 1.00 40.80  ? 371 ALA C CB  1 
ATOM   9669  N N   . LEU C 1 351 ? 197.387 153.121 173.890 1.00 34.58  ? 372 LEU C N   1 
ATOM   9670  C CA  . LEU C 1 351 ? 197.643 151.716 174.169 1.00 34.58  ? 372 LEU C CA  1 
ATOM   9671  C C   . LEU C 1 351 ? 196.320 150.969 174.124 1.00 34.58  ? 372 LEU C C   1 
ATOM   9672  O O   . LEU C 1 351 ? 195.322 151.446 174.670 1.00 34.58  ? 372 LEU C O   1 
ATOM   9673  C CB  . LEU C 1 351 ? 198.310 151.556 175.545 1.00 34.58  ? 372 LEU C CB  1 
ATOM   9674  C CG  . LEU C 1 351 ? 198.964 150.247 175.999 1.00 34.58  ? 372 LEU C CG  1 
ATOM   9675  C CD1 . LEU C 1 351 ? 200.143 150.571 176.895 1.00 34.58  ? 372 LEU C CD1 1 
ATOM   9676  C CD2 . LEU C 1 351 ? 197.999 149.341 176.741 1.00 34.58  ? 372 LEU C CD2 1 
ATOM   9677  N N   . SER C 1 352 ? 196.312 149.803 173.479 1.00 41.40  ? 373 SER C N   1 
ATOM   9678  C CA  . SER C 1 352 ? 195.113 148.970 173.431 1.00 41.40  ? 373 SER C CA  1 
ATOM   9679  C C   . SER C 1 352 ? 195.547 147.516 173.324 1.00 41.40  ? 373 SER C C   1 
ATOM   9680  O O   . SER C 1 352 ? 196.164 147.134 172.323 1.00 41.40  ? 373 SER C O   1 
ATOM   9681  C CB  . SER C 1 352 ? 194.214 149.366 172.262 1.00 41.40  ? 373 SER C CB  1 
ATOM   9682  O OG  . SER C 1 352 ? 194.621 148.729 171.066 1.00 41.40  ? 373 SER C OG  1 
ATOM   9683  N N   . GLU C 1 353 ? 195.223 146.729 174.361 1.00 46.50  ? 374 GLU C N   1 
ATOM   9684  C CA  . GLU C 1 353 ? 195.525 145.292 174.461 1.00 46.50  ? 374 GLU C CA  1 
ATOM   9685  C C   . GLU C 1 353 ? 197.019 145.004 174.312 1.00 46.50  ? 374 GLU C C   1 
ATOM   9686  O O   . GLU C 1 353 ? 197.419 144.008 173.708 1.00 46.50  ? 374 GLU C O   1 
ATOM   9687  C CB  . GLU C 1 353 ? 194.713 144.474 173.451 1.00 46.50  ? 374 GLU C CB  1 
ATOM   9688  C CG  . GLU C 1 353 ? 193.241 144.335 173.793 1.00 46.50  ? 374 GLU C CG  1 
ATOM   9689  C CD  . GLU C 1 353 ? 192.388 145.391 173.121 1.00 46.50  ? 374 GLU C CD  1 
ATOM   9690  O OE1 . GLU C 1 353 ? 192.906 146.093 172.227 1.00 46.50  ? 374 GLU C OE1 1 
ATOM   9691  O OE2 . GLU C 1 353 ? 191.198 145.516 173.481 1.00 46.50  ? 374 GLU C OE2 1 
ATOM   9692  N N   . GLY C 1 354 ? 197.851 145.880 174.869 1.00 46.52  ? 375 GLY C N   1 
ATOM   9693  C CA  . GLY C 1 354 ? 199.286 145.742 174.733 1.00 46.52  ? 375 GLY C CA  1 
ATOM   9694  C C   . GLY C 1 354 ? 199.848 146.166 173.396 1.00 46.52  ? 375 GLY C C   1 
ATOM   9695  O O   . GLY C 1 354 ? 201.030 145.922 173.132 1.00 46.52  ? 375 GLY C O   1 
ATOM   9696  N N   . VAL C 1 355 ? 199.042 146.793 172.546 1.00 42.38  ? 376 VAL C N   1 
ATOM   9697  C CA  . VAL C 1 355 ? 199.448 147.221 171.214 1.00 42.38  ? 376 VAL C CA  1 
ATOM   9698  C C   . VAL C 1 355 ? 199.483 148.742 171.203 1.00 42.38  ? 376 VAL C C   1 
ATOM   9699  O O   . VAL C 1 355 ? 198.513 149.390 171.617 1.00 42.38  ? 376 VAL C O   1 
ATOM   9700  C CB  . VAL C 1 355 ? 198.486 146.673 170.146 1.00 42.38  ? 376 VAL C CB  1 
ATOM   9701  C CG1 . VAL C 1 355 ? 198.839 147.201 168.774 1.00 42.38  ? 376 VAL C CG1 1 
ATOM   9702  C CG2 . VAL C 1 355 ? 198.504 145.152 170.154 1.00 42.38  ? 376 VAL C CG2 1 
ATOM   9703  N N   . ILE C 1 356 ? 200.597 149.316 170.751 1.00 43.51  ? 377 ILE C N   1 
ATOM   9704  C CA  . ILE C 1 356 ? 200.779 150.763 170.756 1.00 43.51  ? 377 ILE C CA  1 
ATOM   9705  C C   . ILE C 1 356 ? 200.399 151.311 169.390 1.00 43.51  ? 377 ILE C C   1 
ATOM   9706  O O   . ILE C 1 356 ? 200.964 150.902 168.369 1.00 43.51  ? 377 ILE C O   1 
ATOM   9707  C CB  . ILE C 1 356 ? 202.222 151.148 171.118 1.00 43.51  ? 377 ILE C CB  1 
ATOM   9708  C CG1 . ILE C 1 356 ? 202.514 150.791 172.571 1.00 43.51  ? 377 ILE C CG1 1 
ATOM   9709  C CG2 . ILE C 1 356 ? 202.452 152.635 170.897 1.00 43.51  ? 377 ILE C CG2 1 
ATOM   9710  C CD1 . ILE C 1 356 ? 201.562 151.440 173.541 1.00 43.51  ? 377 ILE C CD1 1 
ATOM   9711  N N   . TYR C 1 357 ? 199.443 152.235 169.364 1.00 45.78  ? 378 TYR C N   1 
ATOM   9712  C CA  . TYR C 1 357 ? 199.144 153.001 168.160 1.00 45.78  ? 378 TYR C CA  1 
ATOM   9713  C C   . TYR C 1 357 ? 199.735 154.390 168.354 1.00 45.78  ? 378 TYR C C   1 
ATOM   9714  O O   . TYR C 1 357 ? 199.249 155.166 169.184 1.00 45.78  ? 378 TYR C O   1 
ATOM   9715  C CB  . TYR C 1 357 ? 197.643 153.066 167.895 1.00 45.78  ? 378 TYR C CB  1 
ATOM   9716  C CG  . TYR C 1 357 ? 197.028 151.751 167.475 1.00 45.78  ? 378 TYR C CG  1 
ATOM   9717  C CD1 . TYR C 1 357 ? 197.796 150.761 166.876 1.00 45.78  ? 378 TYR C CD1 1 
ATOM   9718  C CD2 . TYR C 1 357 ? 195.675 151.506 167.666 1.00 45.78  ? 378 TYR C CD2 1 
ATOM   9719  C CE1 . TYR C 1 357 ? 197.234 149.558 166.487 1.00 45.78  ? 378 TYR C CE1 1 
ATOM   9720  C CE2 . TYR C 1 357 ? 195.103 150.307 167.281 1.00 45.78  ? 378 TYR C CE2 1 
ATOM   9721  C CZ  . TYR C 1 357 ? 195.888 149.338 166.693 1.00 45.78  ? 378 TYR C CZ  1 
ATOM   9722  O OH  . TYR C 1 357 ? 195.325 148.144 166.308 1.00 45.78  ? 378 TYR C OH  1 
ATOM   9723  N N   . ALA C 1 358 ? 200.790 154.699 167.601 1.00 58.95  ? 379 ALA C N   1 
ATOM   9724  C CA  . ALA C 1 358 ? 201.532 155.933 167.800 1.00 58.95  ? 379 ALA C CA  1 
ATOM   9725  C C   . ALA C 1 358 ? 201.817 156.593 166.462 1.00 58.95  ? 379 ALA C C   1 
ATOM   9726  O O   . ALA C 1 358 ? 202.157 155.916 165.489 1.00 58.95  ? 379 ALA C O   1 
ATOM   9727  C CB  . ALA C 1 358 ? 202.853 155.674 168.535 1.00 58.95  ? 379 ALA C CB  1 
ATOM   9728  N N   . ASN C 1 359 ? 201.683 157.915 166.422 1.00 66.62  ? 380 ASN C N   1 
ATOM   9729  C CA  . ASN C 1 359 ? 202.093 158.701 165.261 1.00 66.62  ? 380 ASN C CA  1 
ATOM   9730  C C   . ASN C 1 359 ? 203.559 159.061 165.456 1.00 66.62  ? 380 ASN C C   1 
ATOM   9731  O O   . ASN C 1 359 ? 203.892 159.976 166.213 1.00 66.62  ? 380 ASN C O   1 
ATOM   9732  C CB  . ASN C 1 359 ? 201.226 159.945 165.105 1.00 66.62  ? 380 ASN C CB  1 
ATOM   9733  C CG  . ASN C 1 359 ? 201.396 160.606 163.751 1.00 66.62  ? 380 ASN C CG  1 
ATOM   9734  O OD1 . ASN C 1 359 ? 202.086 160.086 162.875 1.00 66.62  ? 380 ASN C OD1 1 
ATOM   9735  N ND2 . ASN C 1 359 ? 200.775 161.766 163.578 1.00 66.62  ? 380 ASN C ND2 1 
ATOM   9736  N N   . CYS C 1 360 ? 204.442 158.343 164.766 1.00 72.13  ? 381 CYS C N   1 
ATOM   9737  C CA  . CYS C 1 360 ? 205.875 158.521 164.958 1.00 72.13  ? 381 CYS C CA  1 
ATOM   9738  C C   . CYS C 1 360 ? 206.448 159.680 164.153 1.00 72.13  ? 381 CYS C C   1 
ATOM   9739  O O   . CYS C 1 360 ? 207.654 159.932 164.241 1.00 72.13  ? 381 CYS C O   1 
ATOM   9740  C CB  . CYS C 1 360 ? 206.618 157.230 164.611 1.00 72.13  ? 381 CYS C CB  1 
ATOM   9741  S SG  . CYS C 1 360 ? 206.357 155.892 165.799 1.00 72.13  ? 381 CYS C SG  1 
ATOM   9742  N N   . LEU C 1 361 ? 205.626 160.383 163.373 1.00 68.99  ? 382 LEU C N   1 
ATOM   9743  C CA  . LEU C 1 361 ? 206.121 161.544 162.641 1.00 68.99  ? 382 LEU C CA  1 
ATOM   9744  C C   . LEU C 1 361 ? 206.317 162.737 163.568 1.00 68.99  ? 382 LEU C C   1 
ATOM   9745  O O   . LEU C 1 361 ? 207.271 163.506 163.406 1.00 68.99  ? 382 LEU C O   1 
ATOM   9746  C CB  . LEU C 1 361 ? 205.162 161.892 161.503 1.00 68.99  ? 382 LEU C CB  1 
ATOM   9747  C CG  . LEU C 1 361 ? 205.644 162.926 160.484 1.00 68.99  ? 382 LEU C CG  1 
ATOM   9748  C CD1 . LEU C 1 361 ? 206.971 162.501 159.877 1.00 68.99  ? 382 LEU C CD1 1 
ATOM   9749  C CD2 . LEU C 1 361 ? 204.600 163.132 159.398 1.00 68.99  ? 382 LEU C CD2 1 
ATOM   9750  N N   . ALA C 1 362 ? 205.429 162.904 164.547 1.00 67.25  ? 383 ALA C N   1 
ATOM   9751  C CA  . ALA C 1 362 ? 205.517 164.005 165.497 1.00 67.25  ? 383 ALA C CA  1 
ATOM   9752  C C   . ALA C 1 362 ? 206.217 163.628 166.794 1.00 67.25  ? 383 ALA C C   1 
ATOM   9753  O O   . ALA C 1 362 ? 206.876 164.480 167.398 1.00 67.25  ? 383 ALA C O   1 
ATOM   9754  C CB  . ALA C 1 362 ? 204.118 164.539 165.823 1.00 67.25  ? 383 ALA C CB  1 
ATOM   9755  N N   . THR C 1 363 ? 206.089 162.381 167.234 1.00 71.00  ? 384 THR C N   1 
ATOM   9756  C CA  . THR C 1 363 ? 206.702 161.903 168.466 1.00 71.00  ? 384 THR C CA  1 
ATOM   9757  C C   . THR C 1 363 ? 207.840 160.955 168.113 1.00 71.00  ? 384 THR C C   1 
ATOM   9758  O O   . THR C 1 363 ? 207.687 160.102 167.234 1.00 71.00  ? 384 THR C O   1 
ATOM   9759  C CB  . THR C 1 363 ? 205.670 161.194 169.348 1.00 71.00  ? 384 THR C CB  1 
ATOM   9760  O OG1 . THR C 1 363 ? 204.500 162.012 169.463 1.00 71.00  ? 384 THR C OG1 1 
ATOM   9761  C CG2 . THR C 1 363 ? 206.228 160.937 170.740 1.00 71.00  ? 384 THR C CG2 1 
ATOM   9762  N N   . SER C 1 364 ? 208.981 161.118 168.780 1.00 73.90  ? 385 SER C N   1 
ATOM   9763  C CA  . SER C 1 364 ? 210.124 160.253 168.522 1.00 73.90  ? 385 SER C CA  1 
ATOM   9764  C C   . SER C 1 364 ? 209.861 158.852 169.062 1.00 73.90  ? 385 SER C C   1 
ATOM   9765  O O   . SER C 1 364 ? 209.496 158.680 170.229 1.00 73.90  ? 385 SER C O   1 
ATOM   9766  C CB  . SER C 1 364 ? 211.385 160.837 169.154 1.00 73.90  ? 385 SER C CB  1 
ATOM   9767  O OG  . SER C 1 364 ? 212.479 159.947 169.022 1.00 73.90  ? 385 SER C OG  1 
ATOM   9768  N N   . CYS C 1 365 ? 210.049 157.850 168.207 1.00 75.68  ? 386 CYS C N   1 
ATOM   9769  C CA  . CYS C 1 365 ? 209.803 156.455 168.543 1.00 75.68  ? 386 CYS C CA  1 
ATOM   9770  C C   . CYS C 1 365 ? 211.121 155.698 168.503 1.00 75.68  ? 386 CYS C C   1 
ATOM   9771  O O   . CYS C 1 365 ? 211.858 155.787 167.516 1.00 75.68  ? 386 CYS C O   1 
ATOM   9772  C CB  . CYS C 1 365 ? 208.807 155.822 167.568 1.00 75.68  ? 386 CYS C CB  1 
ATOM   9773  S SG  . CYS C 1 365 ? 207.172 156.586 167.526 1.00 75.68  ? 386 CYS C SG  1 
ATOM   9774  N N   . LYS C 1 366 ? 211.416 154.953 169.567 1.00 73.71  ? 387 LYS C N   1 
ATOM   9775  C CA  . LYS C 1 366 ? 212.650 154.182 169.629 1.00 73.71  ? 387 LYS C CA  1 
ATOM   9776  C C   . LYS C 1 366 ? 212.382 152.847 170.308 1.00 73.71  ? 387 LYS C C   1 
ATOM   9777  O O   . LYS C 1 366 ? 211.322 152.625 170.896 1.00 73.71  ? 387 LYS C O   1 
ATOM   9778  C CB  . LYS C 1 366 ? 213.755 154.949 170.368 1.00 73.71  ? 387 LYS C CB  1 
ATOM   9779  C CG  . LYS C 1 366 ? 214.592 155.860 169.475 1.00 73.71  ? 387 LYS C CG  1 
ATOM   9780  C CD  . LYS C 1 366 ? 215.499 156.798 170.276 1.00 73.71  ? 387 LYS C CD  1 
ATOM   9781  C CE  . LYS C 1 366 ? 216.198 156.095 171.434 1.00 73.71  ? 387 LYS C CE  1 
ATOM   9782  N NZ  . LYS C 1 366 ? 217.201 155.104 170.957 1.00 73.71  ? 387 LYS C NZ  1 
ATOM   9783  N N   . CYS C 1 367 ? 213.364 151.952 170.230 1.00 78.90  ? 388 CYS C N   1 
ATOM   9784  C CA  . CYS C 1 367 ? 213.314 150.671 170.922 1.00 78.90  ? 388 CYS C CA  1 
ATOM   9785  C C   . CYS C 1 367 ? 214.478 150.586 171.895 1.00 78.90  ? 388 CYS C C   1 
ATOM   9786  O O   . CYS C 1 367 ? 215.622 150.858 171.521 1.00 78.90  ? 388 CYS C O   1 
ATOM   9787  C CB  . CYS C 1 367 ? 213.357 149.503 169.935 1.00 78.90  ? 388 CYS C CB  1 
ATOM   9788  S SG  . CYS C 1 367 ? 211.964 149.471 168.795 1.00 78.90  ? 388 CYS C SG  1 
ATOM   9789  N N   . ALA C 1 368 ? 214.185 150.210 173.139 1.00 74.56  ? 389 ALA C N   1 
ATOM   9790  C CA  . ALA C 1 368 ? 215.222 150.166 174.163 1.00 74.56  ? 389 ALA C CA  1 
ATOM   9791  C C   . ALA C 1 368 ? 216.125 148.948 174.030 1.00 74.56  ? 389 ALA C C   1 
ATOM   9792  O O   . ALA C 1 368 ? 217.297 149.010 174.416 1.00 74.56  ? 389 ALA C O   1 
ATOM   9793  C CB  . ALA C 1 368 ? 214.590 150.189 175.553 1.00 74.56  ? 389 ALA C CB  1 
ATOM   9794  N N   . THR C 1 369 ? 215.605 147.837 173.503 1.00 75.50  ? 390 THR C N   1 
ATOM   9795  C CA  . THR C 1 369 ? 216.386 146.608 173.431 1.00 75.50  ? 390 THR C CA  1 
ATOM   9796  C C   . THR C 1 369 ? 217.463 146.654 172.355 1.00 75.50  ? 390 THR C C   1 
ATOM   9797  O O   . THR C 1 369 ? 218.444 145.909 172.448 1.00 75.50  ? 390 THR C O   1 
ATOM   9798  C CB  . THR C 1 369 ? 215.466 145.412 173.185 1.00 75.50  ? 390 THR C CB  1 
ATOM   9799  O OG1 . THR C 1 369 ? 214.657 145.660 172.028 1.00 75.50  ? 390 THR C OG1 1 
ATOM   9800  C CG2 . THR C 1 369 ? 214.566 145.179 174.388 1.00 75.50  ? 390 THR C CG2 1 
ATOM   9801  N N   . THR C 1 370 ? 217.306 147.506 171.341 1.00 82.37  ? 391 THR C N   1 
ATOM   9802  C CA  . THR C 1 370 ? 218.251 147.581 170.236 1.00 82.37  ? 391 THR C CA  1 
ATOM   9803  C C   . THR C 1 370 ? 218.874 148.953 170.035 1.00 82.37  ? 391 THR C C   1 
ATOM   9804  O O   . THR C 1 370 ? 219.935 149.030 169.403 1.00 82.37  ? 391 THR C O   1 
ATOM   9805  C CB  . THR C 1 370 ? 217.571 147.165 168.922 1.00 82.37  ? 391 THR C CB  1 
ATOM   9806  O OG1 . THR C 1 370 ? 216.372 147.929 168.749 1.00 82.37  ? 391 THR C OG1 1 
ATOM   9807  C CG2 . THR C 1 370 ? 217.231 145.682 168.934 1.00 82.37  ? 391 THR C CG2 1 
ATOM   9808  N N   . ASN C 1 371 ? 218.246 150.019 170.548 1.00 77.72  ? 392 ASN C N   1 
ATOM   9809  C CA  . ASN C 1 371 ? 218.672 151.419 170.407 1.00 77.72  ? 392 ASN C CA  1 
ATOM   9810  C C   . ASN C 1 371 ? 218.797 151.817 168.931 1.00 77.72  ? 392 ASN C C   1 
ATOM   9811  O O   . ASN C 1 371 ? 219.869 152.166 168.432 1.00 77.72  ? 392 ASN C O   1 
ATOM   9812  C CB  . ASN C 1 371 ? 219.966 151.694 171.188 1.00 77.72  ? 392 ASN C CB  1 
ATOM   9813  C CG  . ASN C 1 371 ? 220.264 153.177 171.325 1.00 77.72  ? 392 ASN C CG  1 
ATOM   9814  O OD1 . ASN C 1 371 ? 219.353 153.993 171.466 1.00 77.72  ? 392 ASN C OD1 1 
ATOM   9815  N ND2 . ASN C 1 371 ? 221.543 153.530 171.287 1.00 77.72  ? 392 ASN C ND2 1 
ATOM   9816  N N   . LYS C 1 372 ? 217.667 151.732 168.229 1.00 71.89  ? 393 LYS C N   1 
ATOM   9817  C CA  . LYS C 1 372 ? 217.566 152.207 166.860 1.00 71.89  ? 393 LYS C CA  1 
ATOM   9818  C C   . LYS C 1 372 ? 216.269 152.995 166.726 1.00 71.89  ? 393 LYS C C   1 
ATOM   9819  O O   . LYS C 1 372 ? 215.266 152.648 167.367 1.00 71.89  ? 393 LYS C O   1 
ATOM   9820  C CB  . LYS C 1 372 ? 217.597 151.062 165.834 1.00 71.89  ? 393 LYS C CB  1 
ATOM   9821  C CG  . LYS C 1 372 ? 216.618 149.926 166.090 1.00 71.89  ? 393 LYS C CG  1 
ATOM   9822  C CD  . LYS C 1 372 ? 216.867 148.772 165.129 1.00 71.89  ? 393 LYS C CD  1 
ATOM   9823  C CE  . LYS C 1 372 ? 216.036 147.549 165.484 1.00 71.89  ? 393 LYS C CE  1 
ATOM   9824  N NZ  . LYS C 1 372 ? 214.574 147.820 165.396 1.00 71.89  ? 393 LYS C NZ  1 
ATOM   9825  N N   . PRO C 1 373 ? 216.259 154.063 165.931 1.00 71.82  ? 394 PRO C N   1 
ATOM   9826  C CA  . PRO C 1 373 ? 215.024 154.831 165.752 1.00 71.82  ? 394 PRO C CA  1 
ATOM   9827  C C   . PRO C 1 373 ? 214.030 154.105 164.860 1.00 71.82  ? 394 PRO C C   1 
ATOM   9828  O O   . PRO C 1 373 ? 214.378 153.226 164.068 1.00 71.82  ? 394 PRO C O   1 
ATOM   9829  C CB  . PRO C 1 373 ? 215.505 156.131 165.101 1.00 71.82  ? 394 PRO C CB  1 
ATOM   9830  C CG  . PRO C 1 373 ? 216.757 155.748 164.398 1.00 71.82  ? 394 PRO C CG  1 
ATOM   9831  C CD  . PRO C 1 373 ? 217.405 154.703 165.260 1.00 71.82  ? 394 PRO C CD  1 
ATOM   9832  N N   . ILE C 1 374 ? 212.766 154.493 165.003 1.00 76.58  ? 395 ILE C N   1 
ATOM   9833  C CA  . ILE C 1 374 ? 211.669 153.962 164.203 1.00 76.58  ? 395 ILE C CA  1 
ATOM   9834  C C   . ILE C 1 374 ? 211.182 155.065 163.276 1.00 76.58  ? 395 ILE C C   1 
ATOM   9835  O O   . ILE C 1 374 ? 210.864 156.171 163.729 1.00 76.58  ? 395 ILE C O   1 
ATOM   9836  C CB  . ILE C 1 374 ? 210.525 153.436 165.087 1.00 76.58  ? 395 ILE C CB  1 
ATOM   9837  C CG1 . ILE C 1 374 ? 211.082 152.580 166.226 1.00 76.58  ? 395 ILE C CG1 1 
ATOM   9838  C CG2 . ILE C 1 374 ? 209.534 152.641 164.254 1.00 76.58  ? 395 ILE C CG2 1 
ATOM   9839  C CD1 . ILE C 1 374 ? 210.085 152.310 167.324 1.00 76.58  ? 395 ILE C CD1 1 
ATOM   9840  N N   . VAL C 1 375 ? 211.121 154.764 161.983 1.00 73.32  ? 396 VAL C N   1 
ATOM   9841  C CA  . VAL C 1 375 ? 210.773 155.741 160.960 1.00 73.32  ? 396 VAL C CA  1 
ATOM   9842  C C   . VAL C 1 375 ? 209.348 155.461 160.486 1.00 73.32  ? 396 VAL C C   1 
ATOM   9843  O O   . VAL C 1 375 ? 208.868 154.321 160.528 1.00 73.32  ? 396 VAL C O   1 
ATOM   9844  C CB  . VAL C 1 375 ? 211.813 155.701 159.808 1.00 73.32  ? 396 VAL C CB  1 
ATOM   9845  C CG1 . VAL C 1 375 ? 211.780 154.368 159.058 1.00 73.32  ? 396 VAL C CG1 1 
ATOM   9846  C CG2 . VAL C 1 375 ? 211.695 156.904 158.856 1.00 73.32  ? 396 VAL C CG2 1 
ATOM   9847  N N   . GLN C 1 376 ? 208.652 156.525 160.086 1.00 74.61  ? 397 GLN C N   1 
ATOM   9848  C CA  . GLN C 1 376 ? 207.300 156.399 159.559 1.00 74.61  ? 397 GLN C CA  1 
ATOM   9849  C C   . GLN C 1 376 ? 207.321 155.726 158.194 1.00 74.61  ? 397 GLN C C   1 
ATOM   9850  O O   . GLN C 1 376 ? 208.075 156.129 157.303 1.00 74.61  ? 397 GLN C O   1 
ATOM   9851  C CB  . GLN C 1 376 ? 206.647 157.775 159.440 1.00 74.61  ? 397 GLN C CB  1 
ATOM   9852  C CG  . GLN C 1 376 ? 206.023 158.314 160.711 1.00 74.61  ? 397 GLN C CG  1 
ATOM   9853  C CD  . GLN C 1 376 ? 204.705 157.649 161.043 1.00 74.61  ? 397 GLN C CD  1 
ATOM   9854  O OE1 . GLN C 1 376 ? 204.609 156.885 161.998 1.00 74.61  ? 397 GLN C OE1 1 
ATOM   9855  N NE2 . GLN C 1 376 ? 203.681 157.932 160.246 1.00 74.61  ? 397 GLN C NE2 1 
ATOM   9856  N N   . SER C 1 377 ? 206.492 154.701 158.029 1.00 77.03  ? 398 SER C N   1 
ATOM   9857  C CA  . SER C 1 377 ? 206.302 154.108 156.716 1.00 77.03  ? 398 SER C CA  1 
ATOM   9858  C C   . SER C 1 377 ? 205.433 155.016 155.854 1.00 77.03  ? 398 SER C C   1 
ATOM   9859  O O   . SER C 1 377 ? 204.513 155.677 156.341 1.00 77.03  ? 398 SER C O   1 
ATOM   9860  C CB  . SER C 1 377 ? 205.663 152.726 156.837 1.00 77.03  ? 398 SER C CB  1 
ATOM   9861  O OG  . SER C 1 377 ? 205.427 152.163 155.558 1.00 77.03  ? 398 SER C OG  1 
ATOM   9862  N N   . THR C 1 378 ? 205.740 155.052 154.557 1.00 75.12  ? 399 THR C N   1 
ATOM   9863  C CA  . THR C 1 378 ? 204.996 155.905 153.639 1.00 75.12  ? 399 THR C CA  1 
ATOM   9864  C C   . THR C 1 378 ? 203.626 155.342 153.286 1.00 75.12  ? 399 THR C C   1 
ATOM   9865  O O   . THR C 1 378 ? 202.764 156.095 152.821 1.00 75.12  ? 399 THR C O   1 
ATOM   9866  C CB  . THR C 1 378 ? 205.798 156.130 152.355 1.00 75.12  ? 399 THR C CB  1 
ATOM   9867  O OG1 . THR C 1 378 ? 205.882 154.903 151.620 1.00 75.12  ? 399 THR C OG1 1 
ATOM   9868  C CG2 . THR C 1 378 ? 207.202 156.618 152.682 1.00 75.12  ? 399 THR C CG2 1 
ATOM   9869  N N   . SER C 1 379 ? 203.403 154.044 153.497 1.00 78.98  ? 400 SER C N   1 
ATOM   9870  C CA  . SER C 1 379 ? 202.133 153.421 153.152 1.00 78.98  ? 400 SER C CA  1 
ATOM   9871  C C   . SER C 1 379 ? 201.069 153.585 154.230 1.00 78.98  ? 400 SER C C   1 
ATOM   9872  O O   . SER C 1 379 ? 199.910 153.233 153.988 1.00 78.98  ? 400 SER C O   1 
ATOM   9873  C CB  . SER C 1 379 ? 202.342 151.932 152.864 1.00 78.98  ? 400 SER C CB  1 
ATOM   9874  O OG  . SER C 1 379 ? 202.773 151.245 154.025 1.00 78.98  ? 400 SER C OG  1 
ATOM   9875  N N   . THR C 1 380 ? 201.426 154.103 155.403 1.00 80.30  ? 401 THR C N   1 
ATOM   9876  C CA  . THR C 1 380 ? 200.487 154.286 156.499 1.00 80.30  ? 401 THR C CA  1 
ATOM   9877  C C   . THR C 1 380 ? 200.734 155.634 157.162 1.00 80.30  ? 401 THR C C   1 
ATOM   9878  O O   . THR C 1 380 ? 201.733 156.309 156.902 1.00 80.30  ? 401 THR C O   1 
ATOM   9879  C CB  . THR C 1 380 ? 200.604 153.158 157.535 1.00 80.30  ? 401 THR C CB  1 
ATOM   9880  O OG1 . THR C 1 380 ? 199.613 153.337 158.554 1.00 80.30  ? 401 THR C OG1 1 
ATOM   9881  C CG2 . THR C 1 380 ? 201.984 153.164 158.172 1.00 80.30  ? 401 THR C CG2 1 
ATOM   9882  N N   . VAL C 1 381 ? 199.798 156.032 158.021 1.00 71.06  ? 402 VAL C N   1 
ATOM   9883  C CA  . VAL C 1 381 ? 199.902 157.270 158.775 1.00 71.06  ? 402 VAL C CA  1 
ATOM   9884  C C   . VAL C 1 381 ? 200.122 157.006 160.260 1.00 71.06  ? 402 VAL C C   1 
ATOM   9885  O O   . VAL C 1 381 ? 200.971 157.644 160.886 1.00 71.06  ? 402 VAL C O   1 
ATOM   9886  C CB  . VAL C 1 381 ? 198.657 158.158 158.553 1.00 71.06  ? 402 VAL C CB  1 
ATOM   9887  C CG1 . VAL C 1 381 ? 198.921 159.568 159.047 1.00 71.06  ? 402 VAL C CG1 1 
ATOM   9888  C CG2 . VAL C 1 381 ? 198.260 158.174 157.085 1.00 71.06  ? 402 VAL C CG2 1 
ATOM   9889  N N   . ILE C 1 382 ? 199.376 156.066 160.836 1.00 58.10  ? 403 ILE C N   1 
ATOM   9890  C CA  . ILE C 1 382 ? 199.509 155.690 162.239 1.00 58.10  ? 403 ILE C CA  1 
ATOM   9891  C C   . ILE C 1 382 ? 200.327 154.408 162.318 1.00 58.10  ? 403 ILE C C   1 
ATOM   9892  O O   . ILE C 1 382 ? 200.012 153.420 161.645 1.00 58.10  ? 403 ILE C O   1 
ATOM   9893  C CB  . ILE C 1 382 ? 198.132 155.507 162.901 1.00 58.10  ? 403 ILE C CB  1 
ATOM   9894  C CG1 . ILE C 1 382 ? 197.304 156.786 162.780 1.00 58.10  ? 403 ILE C CG1 1 
ATOM   9895  C CG2 . ILE C 1 382 ? 198.283 155.114 164.363 1.00 58.10  ? 403 ILE C CG2 1 
ATOM   9896  C CD1 . ILE C 1 382 ? 197.899 157.969 163.506 1.00 58.10  ? 403 ILE C CD1 1 
ATOM   9897  N N   . THR C 1 383 ? 201.372 154.421 163.141 1.00 51.95  ? 404 THR C N   1 
ATOM   9898  C CA  . THR C 1 383 ? 202.301 153.306 163.259 1.00 51.95  ? 404 THR C CA  1 
ATOM   9899  C C   . THR C 1 383 ? 201.863 152.367 164.375 1.00 51.95  ? 404 THR C C   1 
ATOM   9900  O O   . THR C 1 383 ? 201.593 152.806 165.500 1.00 51.95  ? 404 THR C O   1 
ATOM   9901  C CB  . THR C 1 383 ? 203.722 153.810 163.519 1.00 51.95  ? 404 THR C CB  1 
ATOM   9902  O OG1 . THR C 1 383 ? 204.100 154.717 162.478 1.00 51.95  ? 404 THR C OG1 1 
ATOM   9903  C CG2 . THR C 1 383 ? 204.718 152.657 163.557 1.00 51.95  ? 404 THR C CG2 1 
ATOM   9904  N N   . MET C 1 384 ? 201.791 151.078 164.053 1.00 47.42  ? 405 MET C N   1 
ATOM   9905  C CA  . MET C 1 384 ? 201.486 150.036 165.018 1.00 47.42  ? 405 MET C CA  1 
ATOM   9906  C C   . MET C 1 384 ? 202.798 149.502 165.581 1.00 47.42  ? 405 MET C C   1 
ATOM   9907  O O   . MET C 1 384 ? 203.783 149.344 164.855 1.00 47.42  ? 405 MET C O   1 
ATOM   9908  C CB  . MET C 1 384 ? 200.654 148.941 164.333 1.00 47.42  ? 405 MET C CB  1 
ATOM   9909  C CG  . MET C 1 384 ? 200.127 147.721 165.128 1.00 47.42  ? 405 MET C CG  1 
ATOM   9910  S SD  . MET C 1 384 ? 201.206 146.604 166.042 1.00 47.42  ? 405 MET C SD  1 
ATOM   9911  C CE  . MET C 1 384 ? 202.197 145.998 164.687 1.00 47.42  ? 405 MET C CE  1 
ATOM   9912  N N   . ILE C 1 385 ? 202.805 149.238 166.886 1.00 49.82  ? 406 ILE C N   1 
ATOM   9913  C CA  . ILE C 1 385 ? 203.969 148.704 167.586 1.00 49.82  ? 406 ILE C CA  1 
ATOM   9914  C C   . ILE C 1 385 ? 203.507 147.540 168.454 1.00 49.82  ? 406 ILE C C   1 
ATOM   9915  O O   . ILE C 1 385 ? 202.597 147.699 169.281 1.00 49.82  ? 406 ILE C O   1 
ATOM   9916  C CB  . ILE C 1 385 ? 204.672 149.777 168.439 1.00 49.82  ? 406 ILE C CB  1 
ATOM   9917  C CG1 . ILE C 1 385 ? 205.408 150.785 167.552 1.00 49.82  ? 406 ILE C CG1 1 
ATOM   9918  C CG2 . ILE C 1 385 ? 205.657 149.144 169.400 1.00 49.82  ? 406 ILE C CG2 1 
ATOM   9919  C CD1 . ILE C 1 385 ? 206.013 151.954 168.314 1.00 49.82  ? 406 ILE C CD1 1 
ATOM   9920  N N   . ASP C 1 386 ? 204.120 146.371 168.252 1.00 62.33  ? 407 ASP C N   1 
ATOM   9921  C CA  . ASP C 1 386 ? 203.880 145.197 169.083 1.00 62.33  ? 407 ASP C CA  1 
ATOM   9922  C C   . ASP C 1 386 ? 205.207 144.596 169.528 1.00 62.33  ? 407 ASP C C   1 
ATOM   9923  O O   . ASP C 1 386 ? 206.261 145.217 169.358 1.00 62.33  ? 407 ASP C O   1 
ATOM   9924  C CB  . ASP C 1 386 ? 203.045 144.159 168.332 1.00 62.33  ? 407 ASP C CB  1 
ATOM   9925  C CG  . ASP C 1 386 ? 203.650 143.772 166.997 1.00 62.33  ? 407 ASP C CG  1 
ATOM   9926  O OD1 . ASP C 1 386 ? 204.557 144.483 166.512 1.00 62.33  ? 407 ASP C OD1 1 
ATOM   9927  O OD2 . ASP C 1 386 ? 203.199 142.766 166.413 1.00 62.33  ? 407 ASP C OD2 1 
ATOM   9928  N N   . ASN C 1 387 ? 205.169 143.390 170.099 1.00 68.60  ? 408 ASN C N   1 
ATOM   9929  C CA  . ASN C 1 387 ? 206.391 142.713 170.520 1.00 68.60  ? 408 ASN C CA  1 
ATOM   9930  C C   . ASN C 1 387 ? 207.213 142.183 169.353 1.00 68.60  ? 408 ASN C C   1 
ATOM   9931  O O   . ASN C 1 387 ? 208.383 141.837 169.553 1.00 68.60  ? 408 ASN C O   1 
ATOM   9932  C CB  . ASN C 1 387 ? 206.052 141.569 171.477 1.00 68.60  ? 408 ASN C CB  1 
ATOM   9933  C CG  . ASN C 1 387 ? 204.899 140.717 170.984 1.00 68.60  ? 408 ASN C CG  1 
ATOM   9934  O OD1 . ASN C 1 387 ? 204.354 140.949 169.904 1.00 68.60  ? 408 ASN C OD1 1 
ATOM   9935  N ND2 . ASN C 1 387 ? 204.518 139.723 171.778 1.00 68.60  ? 408 ASN C ND2 1 
ATOM   9936  N N   . SER C 1 388 ? 206.635 142.104 168.151 1.00 67.98  ? 409 SER C N   1 
ATOM   9937  C CA  . SER C 1 388 ? 207.397 141.673 166.985 1.00 67.98  ? 409 SER C CA  1 
ATOM   9938  C C   . SER C 1 388 ? 208.411 142.725 166.556 1.00 67.98  ? 409 SER C C   1 
ATOM   9939  O O   . SER C 1 388 ? 209.470 142.379 166.020 1.00 67.98  ? 409 SER C O   1 
ATOM   9940  C CB  . SER C 1 388 ? 206.448 141.347 165.833 1.00 67.98  ? 409 SER C CB  1 
ATOM   9941  O OG  . SER C 1 388 ? 205.596 140.266 166.169 1.00 67.98  ? 409 SER C OG  1 
ATOM   9942  N N   . LYS C 1 389 ? 208.106 144.004 166.775 1.00 70.49  ? 410 LYS C N   1 
ATOM   9943  C CA  . LYS C 1 389 ? 209.073 145.060 166.497 1.00 70.49  ? 410 LYS C CA  1 
ATOM   9944  C C   . LYS C 1 389 ? 210.176 145.079 167.549 1.00 70.49  ? 410 LYS C C   1 
ATOM   9945  O O   . LYS C 1 389 ? 211.347 144.826 167.241 1.00 70.49  ? 410 LYS C O   1 
ATOM   9946  C CB  . LYS C 1 389 ? 208.365 146.417 166.440 1.00 70.49  ? 410 LYS C CB  1 
ATOM   9947  C CG  . LYS C 1 389 ? 207.253 146.509 165.406 1.00 70.49  ? 410 LYS C CG  1 
ATOM   9948  C CD  . LYS C 1 389 ? 207.803 146.584 163.992 1.00 70.49  ? 410 LYS C CD  1 
ATOM   9949  C CE  . LYS C 1 389 ? 206.690 146.830 162.986 1.00 70.49  ? 410 LYS C CE  1 
ATOM   9950  N NZ  . LYS C 1 389 ? 207.201 146.894 161.589 1.00 70.49  ? 410 LYS C NZ  1 
ATOM   9951  N N   . CYS C 1 390 ? 209.808 145.349 168.808 1.00 74.52  ? 411 CYS C N   1 
ATOM   9952  C CA  . CYS C 1 390 ? 210.726 145.425 169.939 1.00 74.52  ? 411 CYS C CA  1 
ATOM   9953  C C   . CYS C 1 390 ? 209.925 145.378 171.228 1.00 74.52  ? 411 CYS C C   1 
ATOM   9954  O O   . CYS C 1 390 ? 208.815 145.926 171.267 1.00 74.52  ? 411 CYS C O   1 
ATOM   9955  C CB  . CYS C 1 390 ? 211.577 146.700 169.887 1.00 74.52  ? 411 CYS C CB  1 
ATOM   9956  S SG  . CYS C 1 390 ? 210.644 148.231 169.712 1.00 74.52  ? 411 CYS C SG  1 
ATOM   9957  N N   . PRO C 1 391 ? 210.433 144.725 172.288 1.00 62.06  ? 412 PRO C N   1 
ATOM   9958  C CA  . PRO C 1 391 ? 209.664 144.617 173.538 1.00 62.06  ? 412 PRO C CA  1 
ATOM   9959  C C   . PRO C 1 391 ? 209.494 145.927 174.295 1.00 62.06  ? 412 PRO C C   1 
ATOM   9960  O O   . PRO C 1 391 ? 208.373 146.288 174.664 1.00 62.06  ? 412 PRO C O   1 
ATOM   9961  C CB  . PRO C 1 391 ? 210.483 143.612 174.361 1.00 62.06  ? 412 PRO C CB  1 
ATOM   9962  C CG  . PRO C 1 391 ? 211.308 142.872 173.355 1.00 62.06  ? 412 PRO C CG  1 
ATOM   9963  C CD  . PRO C 1 391 ? 211.648 143.896 172.323 1.00 62.06  ? 412 PRO C CD  1 
ATOM   9964  N N   . VAL C 1 392 ? 210.585 146.645 174.539 1.00 65.08  ? 413 VAL C N   1 
ATOM   9965  C CA  . VAL C 1 392 ? 210.556 147.873 175.326 1.00 65.08  ? 413 VAL C CA  1 
ATOM   9966  C C   . VAL C 1 392 ? 210.660 149.053 174.371 1.00 65.08  ? 413 VAL C C   1 
ATOM   9967  O O   . VAL C 1 392 ? 211.590 149.127 173.559 1.00 65.08  ? 413 VAL C O   1 
ATOM   9968  C CB  . VAL C 1 392 ? 211.683 147.901 176.369 1.00 65.08  ? 413 VAL C CB  1 
ATOM   9969  C CG1 . VAL C 1 392 ? 211.460 149.036 177.353 1.00 65.08  ? 413 VAL C CG1 1 
ATOM   9970  C CG2 . VAL C 1 392 ? 211.762 146.568 177.091 1.00 65.08  ? 413 VAL C CG2 1 
ATOM   9971  N N   . VAL C 1 393 ? 209.705 149.976 174.467 1.00 64.37  ? 414 VAL C N   1 
ATOM   9972  C CA  . VAL C 1 393 ? 209.527 151.042 173.489 1.00 64.37  ? 414 VAL C CA  1 
ATOM   9973  C C   . VAL C 1 393 ? 209.718 152.386 174.182 1.00 64.37  ? 414 VAL C C   1 
ATOM   9974  O O   . VAL C 1 393 ? 209.169 152.618 175.267 1.00 64.37  ? 414 VAL C O   1 
ATOM   9975  C CB  . VAL C 1 393 ? 208.141 150.968 172.819 1.00 64.37  ? 414 VAL C CB  1 
ATOM   9976  C CG1 . VAL C 1 393 ? 208.079 151.892 171.620 1.00 64.37  ? 414 VAL C CG1 1 
ATOM   9977  C CG2 . VAL C 1 393 ? 207.808 149.543 172.412 1.00 64.37  ? 414 VAL C CG2 1 
ATOM   9978  N N   . GLU C 1 394 ? 210.520 153.253 173.566 1.00 75.86  ? 415 GLU C N   1 
ATOM   9979  C CA  . GLU C 1 394 ? 210.654 154.653 173.955 1.00 75.86  ? 415 GLU C CA  1 
ATOM   9980  C C   . GLU C 1 394 ? 209.637 155.462 173.157 1.00 75.86  ? 415 GLU C C   1 
ATOM   9981  O O   . GLU C 1 394 ? 209.731 155.547 171.925 1.00 75.86  ? 415 GLU C O   1 
ATOM   9982  C CB  . GLU C 1 394 ? 212.083 155.133 173.698 1.00 75.86  ? 415 GLU C CB  1 
ATOM   9983  C CG  . GLU C 1 394 ? 212.302 156.646 173.587 1.00 75.86  ? 415 GLU C CG  1 
ATOM   9984  C CD  . GLU C 1 394 ? 212.141 157.395 174.894 1.00 75.86  ? 415 GLU C CD  1 
ATOM   9985  O OE1 . GLU C 1 394 ? 212.303 156.792 175.970 1.00 75.86  ? 415 GLU C OE1 1 
ATOM   9986  O OE2 . GLU C 1 394 ? 211.870 158.608 174.844 1.00 75.86  ? 415 GLU C OE2 1 
ATOM   9987  N N   . VAL C 1 395 ? 208.644 156.020 173.852 1.00 66.72  ? 416 VAL C N   1 
ATOM   9988  C CA  . VAL C 1 395 ? 207.644 156.894 173.240 1.00 66.72  ? 416 VAL C CA  1 
ATOM   9989  C C   . VAL C 1 395 ? 207.586 158.178 174.053 1.00 66.72  ? 416 VAL C C   1 
ATOM   9990  O O   . VAL C 1 395 ? 207.282 158.139 175.251 1.00 66.72  ? 416 VAL C O   1 
ATOM   9991  C CB  . VAL C 1 395 ? 206.251 156.242 173.174 1.00 66.72  ? 416 VAL C CB  1 
ATOM   9992  C CG1 . VAL C 1 395 ? 205.211 157.262 172.741 1.00 66.72  ? 416 VAL C CG1 1 
ATOM   9993  C CG2 . VAL C 1 395 ? 206.251 155.078 172.208 1.00 66.72  ? 416 VAL C CG2 1 
ATOM   9994  N N   . GLY C 1 396 ? 207.851 159.311 173.403 1.00 73.58  ? 417 GLY C N   1 
ATOM   9995  C CA  . GLY C 1 396 ? 207.883 160.568 174.123 1.00 73.58  ? 417 GLY C CA  1 
ATOM   9996  C C   . GLY C 1 396 ? 209.105 160.632 175.010 1.00 73.58  ? 417 GLY C C   1 
ATOM   9997  O O   . GLY C 1 396 ? 210.214 160.908 174.546 1.00 73.58  ? 417 GLY C O   1 
ATOM   9998  N N   . LYS C 1 397 ? 208.889 160.425 176.308 1.00 70.58  ? 418 LYS C N   1 
ATOM   9999  C CA  . LYS C 1 397 ? 209.957 160.150 177.253 1.00 70.58  ? 418 LYS C CA  1 
ATOM   10000 C C   . LYS C 1 397 ? 209.860 158.747 177.843 1.00 70.58  ? 418 LYS C C   1 
ATOM   10001 O O   . LYS C 1 397 ? 210.878 158.214 178.299 1.00 70.58  ? 418 LYS C O   1 
ATOM   10002 C CB  . LYS C 1 397 ? 209.940 161.208 178.378 1.00 70.58  ? 418 LYS C CB  1 
ATOM   10003 C CG  . LYS C 1 397 ? 211.161 161.287 179.315 1.00 70.58  ? 418 LYS C CG  1 
ATOM   10004 C CD  . LYS C 1 397 ? 210.969 160.521 180.627 1.00 70.58  ? 418 LYS C CD  1 
ATOM   10005 C CE  . LYS C 1 397 ? 209.937 161.191 181.519 1.00 70.58  ? 418 LYS C CE  1 
ATOM   10006 N NZ  . LYS C 1 397 ? 209.784 160.484 182.820 1.00 70.58  ? 418 LYS C NZ  1 
ATOM   10007 N N   . GLN C 1 398 ? 208.694 158.110 177.773 1.00 66.56  ? 419 GLN C N   1 
ATOM   10008 C CA  . GLN C 1 398 ? 208.389 156.937 178.580 1.00 66.56  ? 419 GLN C CA  1 
ATOM   10009 C C   . GLN C 1 398 ? 208.926 155.647 177.971 1.00 66.56  ? 419 GLN C C   1 
ATOM   10010 O O   . GLN C 1 398 ? 208.773 155.398 176.767 1.00 66.56  ? 419 GLN C O   1 
ATOM   10011 C CB  . GLN C 1 398 ? 206.877 156.815 178.779 1.00 66.56  ? 419 GLN C CB  1 
ATOM   10012 C CG  . GLN C 1 398 ? 206.145 158.140 178.910 1.00 66.56  ? 419 GLN C CG  1 
ATOM   10013 C CD  . GLN C 1 398 ? 206.290 158.770 180.283 1.00 66.56  ? 419 GLN C CD  1 
ATOM   10014 O OE1 . GLN C 1 398 ? 206.806 158.155 181.216 1.00 66.56  ? 419 GLN C OE1 1 
ATOM   10015 N NE2 . GLN C 1 398 ? 205.824 160.006 180.414 1.00 66.56  ? 419 GLN C NE2 1 
ATOM   10016 N N   . MET C 1 399 ? 209.585 154.854 178.818 1.00 69.69  ? 420 MET C N   1 
ATOM   10017 C CA  . MET C 1 399 ? 209.675 153.410 178.644 1.00 69.69  ? 420 MET C CA  1 
ATOM   10018 C C   . MET C 1 399 ? 208.293 152.784 178.783 1.00 69.69  ? 420 MET C C   1 
ATOM   10019 O O   . MET C 1 399 ? 207.583 153.051 179.757 1.00 69.69  ? 420 MET C O   1 
ATOM   10020 C CB  . MET C 1 399 ? 210.594 152.815 179.713 1.00 69.69  ? 420 MET C CB  1 
ATOM   10021 C CG  . MET C 1 399 ? 212.139 152.837 179.590 1.00 69.69  ? 420 MET C CG  1 
ATOM   10022 S SD  . MET C 1 399 ? 213.025 152.350 178.087 1.00 69.69  ? 420 MET C SD  1 
ATOM   10023 C CE  . MET C 1 399 ? 212.932 153.776 177.026 1.00 69.69  ? 420 MET C CE  1 
ATOM   10024 N N   . ILE C 1 400 ? 207.914 151.933 177.828 1.00 66.98  ? 421 ILE C N   1 
ATOM   10025 C CA  . ILE C 1 400 ? 206.700 151.131 177.944 1.00 66.98  ? 421 ILE C CA  1 
ATOM   10026 C C   . ILE C 1 400 ? 206.982 149.713 177.470 1.00 66.98  ? 421 ILE C C   1 
ATOM   10027 O O   . ILE C 1 400 ? 207.879 149.475 176.655 1.00 66.98  ? 421 ILE C O   1 
ATOM   10028 C CB  . ILE C 1 400 ? 205.510 151.733 177.154 1.00 66.98  ? 421 ILE C CB  1 
ATOM   10029 C CG1 . ILE C 1 400 ? 205.946 152.125 175.743 1.00 66.98  ? 421 ILE C CG1 1 
ATOM   10030 C CG2 . ILE C 1 400 ? 204.860 152.894 177.904 1.00 66.98  ? 421 ILE C CG2 1 
ATOM   10031 C CD1 . ILE C 1 400 ? 204.833 152.658 174.882 1.00 66.98  ? 421 ILE C CD1 1 
ATOM   10032 N N   . SER C 1 401 ? 206.208 148.763 177.993 1.00 58.61  ? 422 SER C N   1 
ATOM   10033 C CA  . SER C 1 401 ? 206.208 147.388 177.509 1.00 58.61  ? 422 SER C CA  1 
ATOM   10034 C C   . SER C 1 401 ? 204.982 147.143 176.644 1.00 58.61  ? 422 SER C C   1 
ATOM   10035 O O   . SER C 1 401 ? 203.937 147.771 176.834 1.00 58.61  ? 422 SER C O   1 
ATOM   10036 C CB  . SER C 1 401 ? 206.229 146.377 178.657 1.00 58.61  ? 422 SER C CB  1 
ATOM   10037 O OG  . SER C 1 401 ? 207.497 146.320 179.281 1.00 58.61  ? 422 SER C OG  1 
ATOM   10038 N N   . VAL C 1 402 ? 205.119 146.226 175.690 1.00 53.28  ? 423 VAL C N   1 
ATOM   10039 C CA  . VAL C 1 402 ? 204.027 145.864 174.793 1.00 53.28  ? 423 VAL C CA  1 
ATOM   10040 C C   . VAL C 1 402 ? 203.715 144.382 174.952 1.00 53.28  ? 423 VAL C C   1 
ATOM   10041 O O   . VAL C 1 402 ? 204.392 143.671 175.704 1.00 53.28  ? 423 VAL C O   1 
ATOM   10042 C CB  . VAL C 1 402 ? 204.374 146.201 173.334 1.00 53.28  ? 423 VAL C CB  1 
ATOM   10043 C CG1 . VAL C 1 402 ? 204.561 147.696 173.162 1.00 53.28  ? 423 VAL C CG1 1 
ATOM   10044 C CG2 . VAL C 1 402 ? 205.634 145.475 172.932 1.00 53.28  ? 423 VAL C CG2 1 
ATOM   10045 N N   . GLY C 1 403 ? 202.695 143.908 174.244 1.00 61.60  ? 424 GLY C N   1 
ATOM   10046 C CA  . GLY C 1 403 ? 202.305 142.514 174.341 1.00 61.60  ? 424 GLY C CA  1 
ATOM   10047 C C   . GLY C 1 403 ? 201.246 142.185 173.315 1.00 61.60  ? 424 GLY C C   1 
ATOM   10048 O O   . GLY C 1 403 ? 200.803 143.047 172.550 1.00 61.60  ? 424 GLY C O   1 
ATOM   10049 N N   . SER C 1 404 ? 200.861 140.909 173.309 1.00 76.13  ? 425 SER C N   1 
ATOM   10050 C CA  . SER C 1 404 ? 199.860 140.280 172.428 1.00 76.13  ? 425 SER C CA  1 
ATOM   10051 C C   . SER C 1 404 ? 200.306 140.452 170.971 1.00 76.13  ? 425 SER C C   1 
ATOM   10052 O O   . SER C 1 404 ? 201.506 140.544 170.679 1.00 76.13  ? 425 SER C O   1 
ATOM   10053 C CB  . SER C 1 404 ? 198.468 140.821 172.744 1.00 76.13  ? 425 SER C CB  1 
ATOM   10054 O OG  . SER C 1 404 ? 197.476 140.214 171.934 1.00 76.13  ? 425 SER C OG  1 
ATOM   10055 N N   . TYR C 1 405 ? 199.359 140.493 170.040 1.00 92.45  ? 426 TYR C N   1 
ATOM   10056 C CA  . TYR C 1 405 ? 199.676 140.635 168.621 1.00 92.45  ? 426 TYR C CA  1 
ATOM   10057 C C   . TYR C 1 405 ? 198.494 141.312 167.939 1.00 92.45  ? 426 TYR C C   1 
ATOM   10058 O O   . TYR C 1 405 ? 197.609 141.865 168.602 1.00 92.45  ? 426 TYR C O   1 
ATOM   10059 C CB  . TYR C 1 405 ? 200.049 139.281 168.004 1.00 92.45  ? 426 TYR C CB  1 
ATOM   10060 C CG  . TYR C 1 405 ? 198.961 138.226 167.988 1.00 92.45  ? 426 TYR C CG  1 
ATOM   10061 C CD1 . TYR C 1 405 ? 198.791 137.363 169.065 1.00 92.45  ? 426 TYR C CD1 1 
ATOM   10062 C CD2 . TYR C 1 405 ? 198.155 138.044 166.871 1.00 92.45  ? 426 TYR C CD2 1 
ATOM   10063 C CE1 . TYR C 1 405 ? 197.810 136.382 169.050 1.00 92.45  ? 426 TYR C CE1 1 
ATOM   10064 C CE2 . TYR C 1 405 ? 197.169 137.073 166.845 1.00 92.45  ? 426 TYR C CE2 1 
ATOM   10065 C CZ  . TYR C 1 405 ? 197.004 136.242 167.935 1.00 92.45  ? 426 TYR C CZ  1 
ATOM   10066 O OH  . TYR C 1 405 ? 196.032 135.269 167.910 1.00 92.45  ? 426 TYR C OH  1 
ATOM   10067 N N   . LEU C 1 406 ? 198.486 141.268 166.604 1.00 93.69  ? 427 LEU C N   1 
ATOM   10068 C CA  . LEU C 1 406 ? 197.545 142.075 165.826 1.00 93.69  ? 427 LEU C CA  1 
ATOM   10069 C C   . LEU C 1 406 ? 196.111 141.584 165.945 1.00 93.69  ? 427 LEU C C   1 
ATOM   10070 O O   . LEU C 1 406 ? 195.182 142.372 165.763 1.00 93.69  ? 427 LEU C O   1 
ATOM   10071 C CB  . LEU C 1 406 ? 197.921 142.077 164.344 1.00 93.69  ? 427 LEU C CB  1 
ATOM   10072 C CG  . LEU C 1 406 ? 199.016 143.008 163.816 1.00 93.69  ? 427 LEU C CG  1 
ATOM   10073 C CD1 . LEU C 1 406 ? 198.637 144.460 164.077 1.00 93.69  ? 427 LEU C CD1 1 
ATOM   10074 C CD2 . LEU C 1 406 ? 200.438 142.665 164.283 1.00 93.69  ? 427 LEU C CD2 1 
ATOM   10075 N N   . GLY C 1 407 ? 195.923 140.315 166.286 1.00 97.36  ? 428 GLY C N   1 
ATOM   10076 C CA  . GLY C 1 407 ? 194.635 139.658 166.308 1.00 97.36  ? 428 GLY C CA  1 
ATOM   10077 C C   . GLY C 1 407 ? 194.210 139.053 164.983 1.00 97.36  ? 428 GLY C C   1 
ATOM   10078 O O   . GLY C 1 407 ? 194.369 137.844 164.793 1.00 97.36  ? 428 GLY C O   1 
ATOM   10079 N N   . GLN C 1 408 ? 193.676 139.851 164.056 1.00 103.00 ? 429 GLN C N   1 
ATOM   10080 C CA  . GLN C 1 408 ? 193.355 139.304 162.742 1.00 103.00 ? 429 GLN C CA  1 
ATOM   10081 C C   . GLN C 1 408 ? 194.030 140.062 161.601 1.00 103.00 ? 429 GLN C C   1 
ATOM   10082 O O   . GLN C 1 408 ? 194.742 139.466 160.787 1.00 103.00 ? 429 GLN C O   1 
ATOM   10083 C CB  . GLN C 1 408 ? 191.838 139.283 162.541 1.00 103.00 ? 429 GLN C CB  1 
ATOM   10084 C CG  . GLN C 1 408 ? 191.400 138.643 161.240 1.00 103.00 ? 429 GLN C CG  1 
ATOM   10085 C CD  . GLN C 1 408 ? 192.140 137.354 160.954 1.00 103.00 ? 429 GLN C CD  1 
ATOM   10086 O OE1 . GLN C 1 408 ? 192.021 136.377 161.693 1.00 103.00 ? 429 GLN C OE1 1 
ATOM   10087 N NE2 . GLN C 1 408 ? 192.925 137.352 159.884 1.00 103.00 ? 429 GLN C NE2 1 
ATOM   10088 N N   . VAL C 1 409 ? 193.817 141.378 161.539 1.00 101.61 ? 430 VAL C N   1 
ATOM   10089 C CA  . VAL C 1 409 ? 194.237 142.214 160.419 1.00 101.61 ? 430 VAL C CA  1 
ATOM   10090 C C   . VAL C 1 409 ? 195.168 143.290 160.972 1.00 101.61 ? 430 VAL C C   1 
ATOM   10091 O O   . VAL C 1 409 ? 194.995 143.755 162.103 1.00 101.61 ? 430 VAL C O   1 
ATOM   10092 C CB  . VAL C 1 409 ? 193.004 142.824 159.691 1.00 101.61 ? 430 VAL C CB  1 
ATOM   10093 C CG1 . VAL C 1 409 ? 193.385 143.677 158.479 1.00 101.61 ? 430 VAL C CG1 1 
ATOM   10094 C CG2 . VAL C 1 409 ? 192.017 141.742 159.268 1.00 101.61 ? 430 VAL C CG2 1 
ATOM   10095 N N   . SER C 1 410 ? 196.194 143.668 160.177 1.00 103.99 ? 431 SER C N   1 
ATOM   10096 C CA  . SER C 1 410 ? 197.160 144.660 160.618 1.00 103.99 ? 431 SER C CA  1 
ATOM   10097 C C   . SER C 1 410 ? 196.916 146.014 159.957 1.00 103.99 ? 431 SER C C   1 
ATOM   10098 O O   . SER C 1 410 ? 196.784 146.091 158.730 1.00 103.99 ? 431 SER C O   1 
ATOM   10099 C CB  . SER C 1 410 ? 198.587 144.198 160.308 1.00 103.99 ? 431 SER C CB  1 
ATOM   10100 O OG  . SER C 1 410 ? 198.780 144.088 158.917 1.00 103.99 ? 431 SER C OG  1 
ATOM   10101 N N   . PRO C 1 411 ? 196.842 147.094 160.742 1.00 96.56  ? 432 PRO C N   1 
ATOM   10102 C CA  . PRO C 1 411 ? 196.757 148.437 160.151 1.00 96.56  ? 432 PRO C CA  1 
ATOM   10103 C C   . PRO C 1 411 ? 198.080 148.959 159.617 1.00 96.56  ? 432 PRO C C   1 
ATOM   10104 O O   . PRO C 1 411 ? 198.090 150.010 158.963 1.00 96.56  ? 432 PRO C O   1 
ATOM   10105 C CB  . PRO C 1 411 ? 196.266 149.299 161.322 1.00 96.56  ? 432 PRO C CB  1 
ATOM   10106 C CG  . PRO C 1 411 ? 196.781 148.595 162.525 1.00 96.56  ? 432 PRO C CG  1 
ATOM   10107 C CD  . PRO C 1 411 ? 196.680 147.129 162.206 1.00 96.56  ? 432 PRO C CD  1 
ATOM   10108 N N   . ASN C 1 412 ? 199.190 148.264 159.876 1.00 96.88  ? 433 ASN C N   1 
ATOM   10109 C CA  . ASN C 1 412 ? 200.501 148.747 159.459 1.00 96.88  ? 433 ASN C CA  1 
ATOM   10110 C C   . ASN C 1 412 ? 200.735 148.601 157.960 1.00 96.88  ? 433 ASN C C   1 
ATOM   10111 O O   . ASN C 1 412 ? 201.552 149.336 157.395 1.00 96.88  ? 433 ASN C O   1 
ATOM   10112 C CB  . ASN C 1 412 ? 201.598 148.017 160.240 1.00 96.88  ? 433 ASN C CB  1 
ATOM   10113 C CG  . ASN C 1 412 ? 201.417 146.504 160.245 1.00 96.88  ? 433 ASN C CG  1 
ATOM   10114 O OD1 . ASN C 1 412 ? 201.381 145.856 159.199 1.00 96.88  ? 433 ASN C OD1 1 
ATOM   10115 N ND2 . ASN C 1 412 ? 201.309 145.936 161.436 1.00 96.88  ? 433 ASN C ND2 1 
ATOM   10116 N N   . ASN C 1 413 ? 200.042 147.670 157.303 1.00 110.74 ? 434 ASN C N   1 
ATOM   10117 C CA  . ASN C 1 413 ? 200.281 147.391 155.894 1.00 110.74 ? 434 ASN C CA  1 
ATOM   10118 C C   . ASN C 1 413 ? 199.118 147.767 154.981 1.00 110.74 ? 434 ASN C C   1 
ATOM   10119 O O   . ASN C 1 413 ? 199.269 147.709 153.755 1.00 110.74 ? 434 ASN C O   1 
ATOM   10120 C CB  . ASN C 1 413 ? 200.694 145.906 155.725 1.00 110.74 ? 434 ASN C CB  1 
ATOM   10121 C CG  . ASN C 1 413 ? 199.581 144.869 156.082 1.00 110.74 ? 434 ASN C CG  1 
ATOM   10122 O OD1 . ASN C 1 413 ? 198.387 145.170 156.136 1.00 110.74 ? 434 ASN C OD1 1 
ATOM   10123 N ND2 . ASN C 1 413 ? 199.995 143.623 156.361 1.00 110.74 ? 434 ASN C ND2 1 
ATOM   10124 N N   . LEU C 1 414 ? 197.972 148.128 155.551 1.00 105.74 ? 435 LEU C N   1 
ATOM   10125 C CA  . LEU C 1 414 ? 196.764 148.391 154.784 1.00 105.74 ? 435 LEU C CA  1 
ATOM   10126 C C   . LEU C 1 414 ? 196.876 149.715 154.033 1.00 105.74 ? 435 LEU C C   1 
ATOM   10127 O O   . LEU C 1 414 ? 197.606 150.625 154.436 1.00 105.74 ? 435 LEU C O   1 
ATOM   10128 C CB  . LEU C 1 414 ? 195.555 148.406 155.722 1.00 105.74 ? 435 LEU C CB  1 
ATOM   10129 C CG  . LEU C 1 414 ? 194.123 148.343 155.186 1.00 105.74 ? 435 LEU C CG  1 
ATOM   10130 C CD1 . LEU C 1 414 ? 194.000 147.295 154.092 1.00 105.74 ? 435 LEU C CD1 1 
ATOM   10131 C CD2 . LEU C 1 414 ? 193.160 148.052 156.324 1.00 105.74 ? 435 LEU C CD2 1 
ATOM   10132 N N   . THR C 1 415 ? 196.150 149.810 152.921 1.00 96.47  ? 436 THR C N   1 
ATOM   10133 C CA  . THR C 1 415 ? 196.099 151.040 152.147 1.00 96.47  ? 436 THR C CA  1 
ATOM   10134 C C   . THR C 1 415 ? 195.328 152.121 152.903 1.00 96.47  ? 436 THR C C   1 
ATOM   10135 O O   . THR C 1 415 ? 194.566 151.849 153.836 1.00 96.47  ? 436 THR C O   1 
ATOM   10136 C CB  . THR C 1 415 ? 195.459 150.791 150.779 1.00 96.47  ? 436 THR C CB  1 
ATOM   10137 O OG1 . THR C 1 415 ? 195.535 151.983 149.988 1.00 96.47  ? 436 THR C OG1 1 
ATOM   10138 C CG2 . THR C 1 415 ? 194.001 150.371 150.926 1.00 96.47  ? 436 THR C CG2 1 
ATOM   10139 N N   . ILE C 1 416 ? 195.546 153.368 152.496 1.00 89.35  ? 437 ILE C N   1 
ATOM   10140 C CA  . ILE C 1 416 ? 194.971 154.527 153.168 1.00 89.35  ? 437 ILE C CA  1 
ATOM   10141 C C   . ILE C 1 416 ? 193.948 155.185 152.247 1.00 89.35  ? 437 ILE C C   1 
ATOM   10142 O O   . ILE C 1 416 ? 194.165 155.304 151.034 1.00 89.35  ? 437 ILE C O   1 
ATOM   10143 C CB  . ILE C 1 416 ? 196.066 155.506 153.639 1.00 89.35  ? 437 ILE C CB  1 
ATOM   10144 C CG1 . ILE C 1 416 ? 196.910 156.053 152.481 1.00 89.35  ? 437 ILE C CG1 1 
ATOM   10145 C CG2 . ILE C 1 416 ? 196.958 154.842 154.679 1.00 89.35  ? 437 ILE C CG2 1 
ATOM   10146 C CD1 . ILE C 1 416 ? 197.831 157.182 152.882 1.00 89.35  ? 437 ILE C CD1 1 
ATOM   10147 N N   . GLU C 1 417 ? 192.792 155.524 152.815 1.00 84.35  ? 438 GLU C N   1 
ATOM   10148 C CA  . GLU C 1 417 ? 191.655 156.119 152.113 1.00 84.35  ? 438 GLU C CA  1 
ATOM   10149 C C   . GLU C 1 417 ? 191.100 157.293 152.910 1.00 84.35  ? 438 GLU C C   1 
ATOM   10150 O O   . GLU C 1 417 ? 189.920 157.312 153.273 1.00 84.35  ? 438 GLU C O   1 
ATOM   10151 C CB  . GLU C 1 417 ? 190.529 155.121 151.835 1.00 84.35  ? 438 GLU C CB  1 
ATOM   10152 C CG  . GLU C 1 417 ? 190.942 153.754 151.311 1.00 84.35  ? 438 GLU C CG  1 
ATOM   10153 C CD  . GLU C 1 417 ? 189.784 152.778 151.270 1.00 84.35  ? 438 GLU C CD  1 
ATOM   10154 O OE1 . GLU C 1 417 ? 188.657 153.176 151.629 1.00 84.35  ? 438 GLU C OE1 1 
ATOM   10155 O OE2 . GLU C 1 417 ? 190.002 151.611 150.881 1.00 84.35  ? 438 GLU C OE2 1 
ATOM   10156 N N   . ILE C 1 418 ? 191.977 158.239 153.267 1.00 83.70  ? 439 ILE C N   1 
ATOM   10157 C CA  . ILE C 1 418 ? 191.571 159.448 153.989 1.00 83.70  ? 439 ILE C CA  1 
ATOM   10158 C C   . ILE C 1 418 ? 190.573 160.232 153.147 1.00 83.70  ? 439 ILE C C   1 
ATOM   10159 O O   . ILE C 1 418 ? 190.854 160.601 152.000 1.00 83.70  ? 439 ILE C O   1 
ATOM   10160 C CB  . ILE C 1 418 ? 192.786 160.320 154.351 1.00 83.70  ? 439 ILE C CB  1 
ATOM   10161 C CG1 . ILE C 1 418 ? 193.737 159.631 155.340 1.00 83.70  ? 439 ILE C CG1 1 
ATOM   10162 C CG2 . ILE C 1 418 ? 192.341 161.664 154.915 1.00 83.70  ? 439 ILE C CG2 1 
ATOM   10163 C CD1 . ILE C 1 418 ? 194.893 158.873 154.716 1.00 83.70  ? 439 ILE C CD1 1 
ATOM   10164 N N   . GLY C 1 419 ? 189.397 160.488 153.718 1.00 80.75  ? 440 GLY C N   1 
ATOM   10165 C CA  . GLY C 1 419 ? 188.291 161.056 152.987 1.00 80.75  ? 440 GLY C CA  1 
ATOM   10166 C C   . GLY C 1 419 ? 188.403 162.551 152.769 1.00 80.75  ? 440 GLY C C   1 
ATOM   10167 O O   . GLY C 1 419 ? 189.493 163.132 152.820 1.00 80.75  ? 440 GLY C O   1 
ATOM   10168 N N   . PRO C 1 420 ? 187.267 163.199 152.496 1.00 82.59  ? 441 PRO C N   1 
ATOM   10169 C CA  . PRO C 1 420 ? 187.298 164.626 152.193 1.00 82.59  ? 441 PRO C CA  1 
ATOM   10170 C C   . PRO C 1 420 ? 187.576 165.445 153.442 1.00 82.59  ? 441 PRO C C   1 
ATOM   10171 O O   . PRO C 1 420 ? 187.178 165.062 154.555 1.00 82.59  ? 441 PRO C O   1 
ATOM   10172 C CB  . PRO C 1 420 ? 185.887 164.901 151.645 1.00 82.59  ? 441 PRO C CB  1 
ATOM   10173 C CG  . PRO C 1 420 ? 185.041 163.873 152.307 1.00 82.59  ? 441 PRO C CG  1 
ATOM   10174 C CD  . PRO C 1 420 ? 185.906 162.645 152.379 1.00 82.59  ? 441 PRO C CD  1 
ATOM   10175 N N   . PRO C 1 421 ? 188.267 166.573 153.306 1.00 81.62  ? 442 PRO C N   1 
ATOM   10176 C CA  . PRO C 1 421 ? 188.466 167.457 154.461 1.00 81.62  ? 442 PRO C CA  1 
ATOM   10177 C C   . PRO C 1 421 ? 187.205 168.236 154.800 1.00 81.62  ? 442 PRO C C   1 
ATOM   10178 O O   . PRO C 1 421 ? 187.003 169.348 154.299 1.00 81.62  ? 442 PRO C O   1 
ATOM   10179 C CB  . PRO C 1 421 ? 189.613 168.371 154.011 1.00 81.62  ? 442 PRO C CB  1 
ATOM   10180 C CG  . PRO C 1 421 ? 189.538 168.379 152.520 1.00 81.62  ? 442 PRO C CG  1 
ATOM   10181 C CD  . PRO C 1 421 ? 188.978 167.047 152.104 1.00 81.62  ? 442 PRO C CD  1 
ATOM   10182 N N   . VAL C 1 422 ? 186.331 167.631 155.614 1.00 93.10  ? 443 VAL C N   1 
ATOM   10183 C CA  . VAL C 1 422 ? 185.086 168.281 156.004 1.00 93.10  ? 443 VAL C CA  1 
ATOM   10184 C C   . VAL C 1 422 ? 185.401 169.502 156.860 1.00 93.10  ? 443 VAL C C   1 
ATOM   10185 O O   . VAL C 1 422 ? 186.389 169.528 157.610 1.00 93.10  ? 443 VAL C O   1 
ATOM   10186 C CB  . VAL C 1 422 ? 184.149 167.299 156.736 1.00 93.10  ? 443 VAL C CB  1 
ATOM   10187 C CG1 . VAL C 1 422 ? 183.755 166.151 155.823 1.00 93.10  ? 443 VAL C CG1 1 
ATOM   10188 C CG2 . VAL C 1 422 ? 184.755 166.768 158.023 1.00 93.10  ? 443 VAL C CG2 1 
ATOM   10189 N N   . TYR C 1 423 ? 184.608 170.546 156.697 1.00 103.91 ? 444 TYR C N   1 
ATOM   10190 C CA  . TYR C 1 423 ? 184.909 171.811 157.335 1.00 103.91 ? 444 TYR C CA  1 
ATOM   10191 C C   . TYR C 1 423 ? 184.178 171.871 158.676 1.00 103.91 ? 444 TYR C C   1 
ATOM   10192 O O   . TYR C 1 423 ? 183.726 170.848 159.201 1.00 103.91 ? 444 TYR C O   1 
ATOM   10193 C CB  . TYR C 1 423 ? 184.568 172.964 156.387 1.00 103.91 ? 444 TYR C CB  1 
ATOM   10194 C CG  . TYR C 1 423 ? 185.461 174.166 156.587 1.00 103.91 ? 444 TYR C CG  1 
ATOM   10195 C CD1 . TYR C 1 423 ? 186.805 174.114 156.228 1.00 103.91 ? 444 TYR C CD1 1 
ATOM   10196 C CD2 . TYR C 1 423 ? 184.970 175.348 157.125 1.00 103.91 ? 444 TYR C CD2 1 
ATOM   10197 C CE1 . TYR C 1 423 ? 187.636 175.200 156.409 1.00 103.91 ? 444 TYR C CE1 1 
ATOM   10198 C CE2 . TYR C 1 423 ? 185.793 176.437 157.313 1.00 103.91 ? 444 TYR C CE2 1 
ATOM   10199 C CZ  . TYR C 1 423 ? 187.124 176.360 156.949 1.00 103.91 ? 444 TYR C CZ  1 
ATOM   10200 O OH  . TYR C 1 423 ? 187.951 177.444 157.129 1.00 103.91 ? 444 TYR C OH  1 
ATOM   10201 N N   . THR C 1 424 ? 184.099 173.074 159.252 1.00 118.40 ? 445 THR C N   1 
ATOM   10202 C CA  . THR C 1 424 ? 183.569 173.333 160.587 1.00 118.40 ? 445 THR C CA  1 
ATOM   10203 C C   . THR C 1 424 ? 182.125 172.878 160.770 1.00 118.40 ? 445 THR C C   1 
ATOM   10204 O O   . THR C 1 424 ? 181.227 173.327 160.055 1.00 118.40 ? 445 THR C O   1 
ATOM   10205 C CB  . THR C 1 424 ? 183.672 174.827 160.906 1.00 118.40 ? 445 THR C CB  1 
ATOM   10206 O OG1 . THR C 1 424 ? 182.989 175.580 159.895 1.00 118.40 ? 445 THR C OG1 1 
ATOM   10207 C CG2 . THR C 1 424 ? 185.128 175.261 160.950 1.00 118.40 ? 445 THR C CG2 1 
ATOM   10208 N N   . GLU C 1 425 ? 181.919 171.960 161.711 1.00 127.11 ? 446 GLU C N   1 
ATOM   10209 C CA  . GLU C 1 425 ? 180.577 171.524 162.096 1.00 127.11 ? 446 GLU C CA  1 
ATOM   10210 C C   . GLU C 1 425 ? 179.628 172.628 162.584 1.00 127.11 ? 446 GLU C C   1 
ATOM   10211 O O   . GLU C 1 425 ? 178.431 172.537 162.262 1.00 127.11 ? 446 GLU C O   1 
ATOM   10212 C CB  . GLU C 1 425 ? 180.691 170.403 163.143 1.00 127.11 ? 446 GLU C CB  1 
ATOM   10213 C CG  . GLU C 1 425 ? 181.275 169.095 162.604 1.00 127.11 ? 446 GLU C CG  1 
ATOM   10214 C CD  . GLU C 1 425 ? 182.793 169.054 162.628 1.00 127.11 ? 446 GLU C CD  1 
ATOM   10215 O OE1 . GLU C 1 425 ? 183.410 170.009 163.147 1.00 127.11 ? 446 GLU C OE1 1 
ATOM   10216 O OE2 . GLU C 1 425 ? 183.369 168.070 162.120 1.00 127.11 ? 446 GLU C OE2 1 
ATOM   10217 N N   . PRO C 1 426 ? 180.051 173.686 163.356 1.00 125.30 ? 447 PRO C N   1 
ATOM   10218 C CA  . PRO C 1 426 ? 179.090 174.762 163.657 1.00 125.30 ? 447 PRO C CA  1 
ATOM   10219 C C   . PRO C 1 426 ? 178.731 175.659 162.478 1.00 125.30 ? 447 PRO C C   1 
ATOM   10220 O O   . PRO C 1 426 ? 179.082 175.381 161.327 1.00 125.30 ? 447 PRO C O   1 
ATOM   10221 C CB  . PRO C 1 426 ? 179.796 175.561 164.761 1.00 125.30 ? 447 PRO C CB  1 
ATOM   10222 C CG  . PRO C 1 426 ? 181.224 175.300 164.544 1.00 125.30 ? 447 PRO C CG  1 
ATOM   10223 C CD  . PRO C 1 426 ? 181.243 173.844 164.219 1.00 125.30 ? 447 PRO C CD  1 
ATOM   10224 N N   . VAL C 1 427 ? 178.026 176.755 162.786 1.00 116.86 ? 448 VAL C N   1 
ATOM   10225 C CA  . VAL C 1 427 ? 177.293 177.584 161.825 1.00 116.86 ? 448 VAL C CA  1 
ATOM   10226 C C   . VAL C 1 427 ? 178.192 178.258 160.779 1.00 116.86 ? 448 VAL C C   1 
ATOM   10227 O O   . VAL C 1 427 ? 177.695 178.697 159.732 1.00 116.86 ? 448 VAL C O   1 
ATOM   10228 C CB  . VAL C 1 427 ? 176.466 178.618 162.640 1.00 116.86 ? 448 VAL C CB  1 
ATOM   10229 C CG1 . VAL C 1 427 ? 177.379 179.626 163.341 1.00 116.86 ? 448 VAL C CG1 1 
ATOM   10230 C CG2 . VAL C 1 427 ? 175.355 179.297 161.821 1.00 116.86 ? 448 VAL C CG2 1 
ATOM   10231 N N   . ASP C 1 428 ? 179.512 178.306 161.020 1.00 105.37 ? 449 ASP C N   1 
ATOM   10232 C CA  . ASP C 1 428 ? 180.455 179.003 160.143 1.00 105.37 ? 449 ASP C CA  1 
ATOM   10233 C C   . ASP C 1 428 ? 180.483 178.426 158.728 1.00 105.37 ? 449 ASP C C   1 
ATOM   10234 O O   . ASP C 1 428 ? 180.692 179.176 157.764 1.00 105.37 ? 449 ASP C O   1 
ATOM   10235 C CB  . ASP C 1 428 ? 181.855 178.960 160.764 1.00 105.37 ? 449 ASP C CB  1 
ATOM   10236 C CG  . ASP C 1 428 ? 182.903 179.638 159.902 1.00 105.37 ? 449 ASP C CG  1 
ATOM   10237 O OD1 . ASP C 1 428 ? 182.713 180.820 159.548 1.00 105.37 ? 449 ASP C OD1 1 
ATOM   10238 O OD2 . ASP C 1 428 ? 183.915 178.983 159.573 1.00 105.37 ? 449 ASP C OD2 1 
ATOM   10239 N N   . ILE C 1 429 ? 180.224 177.117 158.584 1.00 106.64 ? 450 ILE C N   1 
ATOM   10240 C CA  . ILE C 1 429 ? 180.159 176.480 157.267 1.00 106.64 ? 450 ILE C CA  1 
ATOM   10241 C C   . ILE C 1 429 ? 179.019 177.062 156.434 1.00 106.64 ? 450 ILE C C   1 
ATOM   10242 O O   . ILE C 1 429 ? 179.156 177.208 155.213 1.00 106.64 ? 450 ILE C O   1 
ATOM   10243 C CB  . ILE C 1 429 ? 180.059 174.938 157.409 1.00 106.64 ? 450 ILE C CB  1 
ATOM   10244 C CG1 . ILE C 1 429 ? 180.152 174.230 156.051 1.00 106.64 ? 450 ILE C CG1 1 
ATOM   10245 C CG2 . ILE C 1 429 ? 178.795 174.489 158.145 1.00 106.64 ? 450 ILE C CG2 1 
ATOM   10246 C CD1 . ILE C 1 429 ? 181.389 174.569 155.255 1.00 106.64 ? 450 ILE C CD1 1 
ATOM   10247 N N   . THR C 1 430 ? 177.917 177.472 157.084 1.00 103.68 ? 451 THR C N   1 
ATOM   10248 C CA  . THR C 1 430 ? 176.831 178.147 156.380 1.00 103.68 ? 451 THR C CA  1 
ATOM   10249 C C   . THR C 1 430 ? 177.286 179.486 155.823 1.00 103.68 ? 451 THR C C   1 
ATOM   10250 O O   . THR C 1 430 ? 176.862 179.872 154.726 1.00 103.68 ? 451 THR C O   1 
ATOM   10251 C CB  . THR C 1 430 ? 175.632 178.343 157.307 1.00 103.68 ? 451 THR C CB  1 
ATOM   10252 O OG1 . THR C 1 430 ? 175.938 179.344 158.287 1.00 103.68 ? 451 THR C OG1 1 
ATOM   10253 C CG2 . THR C 1 430 ? 175.282 177.041 158.007 1.00 103.68 ? 451 THR C CG2 1 
ATOM   10254 N N   . ASN C 1 431 ? 178.174 180.180 156.548 1.00 97.22  ? 452 ASN C N   1 
ATOM   10255 C CA  . ASN C 1 431 ? 178.835 181.357 155.996 1.00 97.22  ? 452 ASN C CA  1 
ATOM   10256 C C   . ASN C 1 431 ? 179.662 180.986 154.774 1.00 97.22  ? 452 ASN C C   1 
ATOM   10257 O O   . ASN C 1 431 ? 179.654 181.708 153.767 1.00 97.22  ? 452 ASN C O   1 
ATOM   10258 C CB  . ASN C 1 431 ? 179.709 182.014 157.062 1.00 97.22  ? 452 ASN C CB  1 
ATOM   10259 C CG  . ASN C 1 431 ? 180.585 183.112 156.499 1.00 97.22  ? 452 ASN C CG  1 
ATOM   10260 O OD1 . ASN C 1 431 ? 180.091 184.089 155.938 1.00 97.22  ? 452 ASN C OD1 1 
ATOM   10261 N ND2 . ASN C 1 431 ? 181.894 182.961 156.654 1.00 97.22  ? 452 ASN C ND2 1 
ATOM   10262 N N   . GLN C 1 432 ? 180.351 179.840 154.835 1.00 104.59 ? 453 GLN C N   1 
ATOM   10263 C CA  . GLN C 1 432 ? 180.956 179.267 153.638 1.00 104.59 ? 453 GLN C CA  1 
ATOM   10264 C C   . GLN C 1 432 ? 179.900 178.924 152.598 1.00 104.59 ? 453 GLN C C   1 
ATOM   10265 O O   . GLN C 1 432 ? 180.075 179.240 151.417 1.00 104.59 ? 453 GLN C O   1 
ATOM   10266 C CB  . GLN C 1 432 ? 181.787 178.035 153.989 1.00 104.59 ? 453 GLN C CB  1 
ATOM   10267 C CG  . GLN C 1 432 ? 183.226 178.352 154.346 1.00 104.59 ? 453 GLN C CG  1 
ATOM   10268 C CD  . GLN C 1 432 ? 183.356 179.088 155.657 1.00 104.59 ? 453 GLN C CD  1 
ATOM   10269 O OE1 . GLN C 1 432 ? 183.784 180.242 155.694 1.00 104.59 ? 453 GLN C OE1 1 
ATOM   10270 N NE2 . GLN C 1 432 ? 183.009 178.419 156.746 1.00 104.59 ? 453 GLN C NE2 1 
ATOM   10271 N N   . LEU C 1 433 ? 178.763 178.345 153.025 1.00 102.78 ? 454 LEU C N   1 
ATOM   10272 C CA  . LEU C 1 433 ? 177.646 178.189 152.094 1.00 102.78 ? 454 LEU C CA  1 
ATOM   10273 C C   . LEU C 1 433 ? 177.143 179.535 151.597 1.00 102.78 ? 454 LEU C C   1 
ATOM   10274 O O   . LEU C 1 433 ? 176.763 179.644 150.421 1.00 102.78 ? 454 LEU C O   1 
ATOM   10275 C CB  . LEU C 1 433 ? 176.500 177.376 152.702 1.00 102.78 ? 454 LEU C CB  1 
ATOM   10276 C CG  . LEU C 1 433 ? 176.524 175.843 152.583 1.00 102.78 ? 454 LEU C CG  1 
ATOM   10277 C CD1 . LEU C 1 433 ? 176.444 175.500 151.103 1.00 102.78 ? 454 LEU C CD1 1 
ATOM   10278 C CD2 . LEU C 1 433 ? 177.699 175.117 153.220 1.00 102.78 ? 454 LEU C CD2 1 
ATOM   10279 N N   . GLY C 1 434 ? 177.254 180.574 152.440 1.00 100.76 ? 455 GLY C N   1 
ATOM   10280 C CA  . GLY C 1 434 ? 176.999 181.933 151.994 1.00 100.76 ? 455 GLY C CA  1 
ATOM   10281 C C   . GLY C 1 434 ? 177.874 182.340 150.827 1.00 100.76 ? 455 GLY C C   1 
ATOM   10282 O O   . GLY C 1 434 ? 177.364 182.761 149.782 1.00 100.76 ? 455 GLY C O   1 
ATOM   10283 N N   . ASN C 1 435 ? 179.193 182.100 150.928 1.00 102.33 ? 456 ASN C N   1 
ATOM   10284 C CA  . ASN C 1 435 ? 179.954 182.475 149.744 1.00 102.33 ? 456 ASN C CA  1 
ATOM   10285 C C   . ASN C 1 435 ? 179.887 181.394 148.674 1.00 102.33 ? 456 ASN C C   1 
ATOM   10286 O O   . ASN C 1 435 ? 180.130 181.705 147.502 1.00 102.33 ? 456 ASN C O   1 
ATOM   10287 C CB  . ASN C 1 435 ? 181.399 182.946 150.093 1.00 102.33 ? 456 ASN C CB  1 
ATOM   10288 C CG  . ASN C 1 435 ? 182.396 181.841 150.525 1.00 102.33 ? 456 ASN C CG  1 
ATOM   10289 O OD1 . ASN C 1 435 ? 182.207 180.645 150.366 1.00 102.33 ? 456 ASN C OD1 1 
ATOM   10290 N ND2 . ASN C 1 435 ? 183.506 182.300 151.085 1.00 102.33 ? 456 ASN C ND2 1 
ATOM   10291 N N   . ILE C 1 436 ? 179.462 180.173 149.039 1.00 107.13 ? 457 ILE C N   1 
ATOM   10292 C CA  . ILE C 1 436 ? 179.085 179.205 148.016 1.00 107.13 ? 457 ILE C CA  1 
ATOM   10293 C C   . ILE C 1 436 ? 177.853 179.709 147.282 1.00 107.13 ? 457 ILE C C   1 
ATOM   10294 O O   . ILE C 1 436 ? 177.766 179.612 146.048 1.00 107.13 ? 457 ILE C O   1 
ATOM   10295 C CB  . ILE C 1 436 ? 178.888 177.801 148.629 1.00 107.13 ? 457 ILE C CB  1 
ATOM   10296 C CG1 . ILE C 1 436 ? 180.245 177.151 148.918 1.00 107.13 ? 457 ILE C CG1 1 
ATOM   10297 C CG2 . ILE C 1 436 ? 178.065 176.878 147.734 1.00 107.13 ? 457 ILE C CG2 1 
ATOM   10298 C CD1 . ILE C 1 436 ? 181.098 176.942 147.685 1.00 107.13 ? 457 ILE C CD1 1 
ATOM   10299 N N   . ASN C 1 437 ? 176.938 180.360 148.019 1.00 112.24 ? 458 ASN C N   1 
ATOM   10300 C CA  . ASN C 1 437 ? 175.843 181.067 147.371 1.00 112.24 ? 458 ASN C CA  1 
ATOM   10301 C C   . ASN C 1 437 ? 176.369 182.218 146.529 1.00 112.24 ? 458 ASN C C   1 
ATOM   10302 O O   . ASN C 1 437 ? 175.876 182.439 145.415 1.00 112.24 ? 458 ASN C O   1 
ATOM   10303 C CB  . ASN C 1 437 ? 174.841 181.577 148.404 1.00 112.24 ? 458 ASN C CB  1 
ATOM   10304 C CG  . ASN C 1 437 ? 173.627 182.217 147.761 1.00 112.24 ? 458 ASN C CG  1 
ATOM   10305 O OD1 . ASN C 1 437 ? 172.795 181.529 147.170 1.00 112.24 ? 458 ASN C OD1 1 
ATOM   10306 N ND2 . ASN C 1 437 ? 173.521 183.535 147.862 1.00 112.24 ? 458 ASN C ND2 1 
ATOM   10307 N N   . GLU C 1 438 ? 177.413 182.908 147.013 1.00 108.68 ? 459 GLU C N   1 
ATOM   10308 C CA  . GLU C 1 438 ? 178.076 183.899 146.176 1.00 108.68 ? 459 GLU C CA  1 
ATOM   10309 C C   . GLU C 1 438 ? 178.791 183.220 145.020 1.00 108.68 ? 459 GLU C C   1 
ATOM   10310 O O   . GLU C 1 438 ? 178.813 183.766 143.912 1.00 108.68 ? 459 GLU C O   1 
ATOM   10311 C CB  . GLU C 1 438 ? 179.038 184.750 147.015 1.00 108.68 ? 459 GLU C CB  1 
ATOM   10312 C CG  . GLU C 1 438 ? 179.870 185.783 146.252 1.00 108.68 ? 459 GLU C CG  1 
ATOM   10313 C CD  . GLU C 1 438 ? 181.252 185.277 145.876 1.00 108.68 ? 459 GLU C CD  1 
ATOM   10314 O OE1 . GLU C 1 438 ? 181.605 184.150 146.284 1.00 108.68 ? 459 GLU C OE1 1 
ATOM   10315 O OE2 . GLU C 1 438 ? 181.982 186.005 145.171 1.00 108.68 ? 459 GLU C OE2 1 
ATOM   10316 N N   . THR C 1 439 ? 179.328 182.013 145.247 1.00 106.57 ? 460 THR C N   1 
ATOM   10317 C CA  . THR C 1 439 ? 179.783 181.188 144.133 1.00 106.57 ? 460 THR C CA  1 
ATOM   10318 C C   . THR C 1 439 ? 178.620 180.879 143.207 1.00 106.57 ? 460 THR C C   1 
ATOM   10319 O O   . THR C 1 439 ? 178.721 181.078 141.989 1.00 106.57 ? 460 THR C O   1 
ATOM   10320 C CB  . THR C 1 439 ? 180.430 179.899 144.641 1.00 106.57 ? 460 THR C CB  1 
ATOM   10321 O OG1 . THR C 1 439 ? 181.548 180.219 145.479 1.00 106.57 ? 460 THR C OG1 1 
ATOM   10322 C CG2 . THR C 1 439 ? 180.902 179.038 143.480 1.00 106.57 ? 460 THR C CG2 1 
ATOM   10323 N N   . LEU C 1 440 ? 177.465 180.518 143.792 1.00 106.86 ? 461 LEU C N   1 
ATOM   10324 C CA  . LEU C 1 440 ? 176.240 180.378 143.013 1.00 106.86 ? 461 LEU C CA  1 
ATOM   10325 C C   . LEU C 1 440 ? 175.888 181.672 142.306 1.00 106.86 ? 461 LEU C C   1 
ATOM   10326 O O   . LEU C 1 440 ? 175.552 181.652 141.115 1.00 106.86 ? 461 LEU C O   1 
ATOM   10327 C CB  . LEU C 1 440 ? 175.071 179.948 143.890 1.00 106.86 ? 461 LEU C CB  1 
ATOM   10328 C CG  . LEU C 1 440 ? 174.988 178.496 144.331 1.00 106.86 ? 461 LEU C CG  1 
ATOM   10329 C CD1 . LEU C 1 440 ? 174.008 178.438 145.468 1.00 106.86 ? 461 LEU C CD1 1 
ATOM   10330 C CD2 . LEU C 1 440 ? 174.552 177.598 143.185 1.00 106.86 ? 461 LEU C CD2 1 
ATOM   10331 N N   . SER C 1 441 ? 176.111 182.805 142.975 1.00 109.00 ? 462 SER C N   1 
ATOM   10332 C CA  . SER C 1 441 ? 175.740 184.078 142.388 1.00 109.00 ? 462 SER C CA  1 
ATOM   10333 C C   . SER C 1 441 ? 176.680 184.479 141.263 1.00 109.00 ? 462 SER C C   1 
ATOM   10334 O O   . SER C 1 441 ? 176.212 184.743 140.157 1.00 109.00 ? 462 SER C O   1 
ATOM   10335 C CB  . SER C 1 441 ? 175.684 185.152 143.480 1.00 109.00 ? 462 SER C CB  1 
ATOM   10336 O OG  . SER C 1 441 ? 175.013 184.670 144.631 1.00 109.00 ? 462 SER C OG  1 
ATOM   10337 N N   . LYS C 1 442 ? 177.984 184.047 141.335 1.00 103.80 ? 463 LYS C N   1 
ATOM   10338 C CA  . LYS C 1 442 ? 178.861 184.152 140.132 1.00 103.80 ? 463 LYS C CA  1 
ATOM   10339 C C   . LYS C 1 442 ? 178.533 183.098 139.086 1.00 103.80 ? 463 LYS C C   1 
ATOM   10340 O O   . LYS C 1 442 ? 178.653 183.394 137.891 1.00 103.80 ? 463 LYS C O   1 
ATOM   10341 C CB  . LYS C 1 442 ? 180.365 184.159 140.481 1.00 103.80 ? 463 LYS C CB  1 
ATOM   10342 C CG  . LYS C 1 442 ? 181.054 182.866 140.840 1.00 103.80 ? 463 LYS C CG  1 
ATOM   10343 C CD  . LYS C 1 442 ? 182.554 183.073 140.996 1.00 103.80 ? 463 LYS C CD  1 
ATOM   10344 C CE  . LYS C 1 442 ? 182.889 183.851 142.261 1.00 103.80 ? 463 LYS C CE  1 
ATOM   10345 N NZ  . LYS C 1 442 ? 182.564 183.096 143.501 1.00 103.80 ? 463 LYS C NZ  1 
ATOM   10346 N N   . THR C 1 443 ? 178.033 181.914 139.480 1.00 103.26 ? 464 THR C N   1 
ATOM   10347 C CA  . THR C 1 443 ? 177.538 181.016 138.438 1.00 103.26 ? 464 THR C CA  1 
ATOM   10348 C C   . THR C 1 443 ? 176.244 181.556 137.853 1.00 103.26 ? 464 THR C C   1 
ATOM   10349 O O   . THR C 1 443 ? 175.992 181.386 136.654 1.00 103.26 ? 464 THR C O   1 
ATOM   10350 C CB  . THR C 1 443 ? 177.333 179.579 138.927 1.00 103.26 ? 464 THR C CB  1 
ATOM   10351 O OG1 . THR C 1 443 ? 176.303 179.533 139.914 1.00 103.26 ? 464 THR C OG1 1 
ATOM   10352 C CG2 . THR C 1 443 ? 178.629 178.988 139.473 1.00 103.26 ? 464 THR C CG2 1 
ATOM   10353 N N   . LEU C 1 444 ? 175.446 182.261 138.673 1.00 101.23 ? 465 LEU C N   1 
ATOM   10354 C CA  . LEU C 1 444 ? 174.349 183.057 138.131 1.00 101.23 ? 465 LEU C CA  1 
ATOM   10355 C C   . LEU C 1 444 ? 174.881 184.125 137.190 1.00 101.23 ? 465 LEU C C   1 
ATOM   10356 O O   . LEU C 1 444 ? 174.306 184.353 136.118 1.00 101.23 ? 465 LEU C O   1 
ATOM   10357 C CB  . LEU C 1 444 ? 173.523 183.694 139.252 1.00 101.23 ? 465 LEU C CB  1 
ATOM   10358 C CG  . LEU C 1 444 ? 172.646 182.808 140.141 1.00 101.23 ? 465 LEU C CG  1 
ATOM   10359 C CD1 . LEU C 1 444 ? 172.055 183.619 141.281 1.00 101.23 ? 465 LEU C CD1 1 
ATOM   10360 C CD2 . LEU C 1 444 ? 171.542 182.160 139.327 1.00 101.23 ? 465 LEU C CD2 1 
ATOM   10361 N N   . ASP C 1 445 ? 176.016 184.740 137.551 1.00 106.43 ? 466 ASP C N   1 
ATOM   10362 C CA  . ASP C 1 445 ? 176.707 185.626 136.622 1.00 106.43 ? 466 ASP C CA  1 
ATOM   10363 C C   . ASP C 1 445 ? 177.183 184.855 135.401 1.00 106.43 ? 466 ASP C C   1 
ATOM   10364 O O   . ASP C 1 445 ? 177.073 185.351 134.274 1.00 106.43 ? 466 ASP C O   1 
ATOM   10365 C CB  . ASP C 1 445 ? 177.879 186.319 137.314 1.00 106.43 ? 466 ASP C CB  1 
ATOM   10366 C CG  . ASP C 1 445 ? 177.429 187.331 138.349 1.00 106.43 ? 466 ASP C CG  1 
ATOM   10367 O OD1 . ASP C 1 445 ? 176.238 187.707 138.336 1.00 106.43 ? 466 ASP C OD1 1 
ATOM   10368 O OD2 . ASP C 1 445 ? 178.265 187.747 139.178 1.00 106.43 ? 466 ASP C OD2 1 
ATOM   10369 N N   . LEU C 1 446 ? 177.660 183.616 135.605 1.00 100.00 ? 467 LEU C N   1 
ATOM   10370 C CA  . LEU C 1 446 ? 177.946 182.738 134.474 1.00 100.00 ? 467 LEU C CA  1 
ATOM   10371 C C   . LEU C 1 446 ? 176.671 182.426 133.705 1.00 100.00 ? 467 LEU C C   1 
ATOM   10372 O O   . LEU C 1 446 ? 176.681 182.404 132.467 1.00 100.00 ? 467 LEU C O   1 
ATOM   10373 C CB  . LEU C 1 446 ? 178.615 181.441 134.938 1.00 100.00 ? 467 LEU C CB  1 
ATOM   10374 C CG  . LEU C 1 446 ? 179.980 181.427 135.644 1.00 100.00 ? 467 LEU C CG  1 
ATOM   10375 C CD1 . LEU C 1 446 ? 180.355 180.007 136.057 1.00 100.00 ? 467 LEU C CD1 1 
ATOM   10376 C CD2 . LEU C 1 446 ? 181.087 182.064 134.830 1.00 100.00 ? 467 LEU C CD2 1 
ATOM   10377 N N   . ILE C 1 447 ? 175.555 182.232 134.428 1.00 100.24 ? 468 ILE C N   1 
ATOM   10378 C CA  . ILE C 1 447 ? 174.245 182.146 133.785 1.00 100.24 ? 468 ILE C CA  1 
ATOM   10379 C C   . ILE C 1 447 ? 173.942 183.445 133.055 1.00 100.24 ? 468 ILE C C   1 
ATOM   10380 O O   . ILE C 1 447 ? 173.520 183.434 131.889 1.00 100.24 ? 468 ILE C O   1 
ATOM   10381 C CB  . ILE C 1 447 ? 173.148 181.785 134.808 1.00 100.24 ? 468 ILE C CB  1 
ATOM   10382 C CG1 . ILE C 1 447 ? 173.268 180.321 135.236 1.00 100.24 ? 468 ILE C CG1 1 
ATOM   10383 C CG2 . ILE C 1 447 ? 171.751 182.042 134.253 1.00 100.24 ? 468 ILE C CG2 1 
ATOM   10384 C CD1 . ILE C 1 447 ? 172.394 179.959 136.411 1.00 100.24 ? 468 ILE C CD1 1 
ATOM   10385 N N   . LYS C 1 448 ? 174.251 184.581 133.690 1.00 100.83 ? 469 LYS C N   1 
ATOM   10386 C CA  . LYS C 1 448 ? 174.152 185.854 132.997 1.00 100.83 ? 469 LYS C CA  1 
ATOM   10387 C C   . LYS C 1 448 ? 175.174 185.977 131.877 1.00 100.83 ? 469 LYS C C   1 
ATOM   10388 O O   . LYS C 1 448 ? 174.859 186.590 130.850 1.00 100.83 ? 469 LYS C O   1 
ATOM   10389 C CB  . LYS C 1 448 ? 174.275 187.013 133.988 1.00 100.83 ? 469 LYS C CB  1 
ATOM   10390 C CG  . LYS C 1 448 ? 173.046 187.149 134.879 1.00 100.83 ? 469 LYS C CG  1 
ATOM   10391 C CD  . LYS C 1 448 ? 173.151 188.306 135.853 1.00 100.83 ? 469 LYS C CD  1 
ATOM   10392 C CE  . LYS C 1 448 ? 171.882 188.417 136.687 1.00 100.83 ? 469 LYS C CE  1 
ATOM   10393 N NZ  . LYS C 1 448 ? 171.947 189.529 137.674 1.00 100.83 ? 469 LYS C NZ  1 
ATOM   10394 N N   . GLN C 1 449 ? 176.352 185.350 132.013 1.00 98.38  ? 470 GLN C N   1 
ATOM   10395 C CA  . GLN C 1 449 ? 177.242 185.259 130.862 1.00 98.38  ? 470 GLN C CA  1 
ATOM   10396 C C   . GLN C 1 449 ? 176.645 184.356 129.797 1.00 98.38  ? 470 GLN C C   1 
ATOM   10397 O O   . GLN C 1 449 ? 176.736 184.657 128.601 1.00 98.38  ? 470 GLN C O   1 
ATOM   10398 C CB  . GLN C 1 449 ? 178.638 184.777 131.257 1.00 98.38  ? 470 GLN C CB  1 
ATOM   10399 C CG  . GLN C 1 449 ? 179.445 185.789 132.049 1.00 98.38  ? 470 GLN C CG  1 
ATOM   10400 C CD  . GLN C 1 449 ? 180.857 185.316 132.316 1.00 98.38  ? 470 GLN C CD  1 
ATOM   10401 O OE1 . GLN C 1 449 ? 181.141 184.122 132.270 1.00 98.38  ? 470 GLN C OE1 1 
ATOM   10402 N NE2 . GLN C 1 449 ? 181.753 186.254 132.598 1.00 98.38  ? 470 GLN C NE2 1 
ATOM   10403 N N   . SER C 1 450 ? 175.961 183.284 130.208 1.00 96.88  ? 471 SER C N   1 
ATOM   10404 C CA  . SER C 1 450 ? 175.224 182.526 129.209 1.00 96.88  ? 471 SER C CA  1 
ATOM   10405 C C   . SER C 1 450 ? 173.921 183.210 128.831 1.00 96.88  ? 471 SER C C   1 
ATOM   10406 O O   . SER C 1 450 ? 173.274 182.776 127.878 1.00 96.88  ? 471 SER C O   1 
ATOM   10407 C CB  . SER C 1 450 ? 174.939 181.096 129.674 1.00 96.88  ? 471 SER C CB  1 
ATOM   10408 O OG  . SER C 1 450 ? 174.012 181.064 130.736 1.00 96.88  ? 471 SER C OG  1 
ATOM   10409 N N   . ASN C 1 451 ? 173.518 184.268 129.544 1.00 98.99  ? 472 ASN C N   1 
ATOM   10410 C CA  . ASN C 1 451 ? 172.497 185.142 128.987 1.00 98.99  ? 472 ASN C CA  1 
ATOM   10411 C C   . ASN C 1 451 ? 173.075 186.008 127.879 1.00 98.99  ? 472 ASN C C   1 
ATOM   10412 O O   . ASN C 1 451 ? 172.337 186.447 126.991 1.00 98.99  ? 472 ASN C O   1 
ATOM   10413 C CB  . ASN C 1 451 ? 171.874 186.011 130.080 1.00 98.99  ? 472 ASN C CB  1 
ATOM   10414 C CG  . ASN C 1 451 ? 170.967 185.221 131.005 1.00 98.99  ? 472 ASN C CG  1 
ATOM   10415 O OD1 . ASN C 1 451 ? 170.456 184.163 130.638 1.00 98.99  ? 472 ASN C OD1 1 
ATOM   10416 N ND2 . ASN C 1 451 ? 170.762 185.733 132.213 1.00 98.99  ? 472 ASN C ND2 1 
ATOM   10417 N N   . SER C 1 452 ? 174.387 186.255 127.912 1.00 98.17  ? 473 SER C N   1 
ATOM   10418 C CA  . SER C 1 452 ? 175.078 186.959 126.842 1.00 98.17  ? 473 SER C CA  1 
ATOM   10419 C C   . SER C 1 452 ? 175.687 186.019 125.808 1.00 98.17  ? 473 SER C C   1 
ATOM   10420 O O   . SER C 1 452 ? 175.919 186.447 124.672 1.00 98.17  ? 473 SER C O   1 
ATOM   10421 C CB  . SER C 1 452 ? 176.175 187.862 127.419 1.00 98.17  ? 473 SER C CB  1 
ATOM   10422 O OG  . SER C 1 452 ? 177.173 187.100 128.072 1.00 98.17  ? 473 SER C OG  1 
ATOM   10423 N N   . ILE C 1 453 ? 175.969 184.765 126.174 1.00 98.14  ? 474 ILE C N   1 
ATOM   10424 C CA  . ILE C 1 453 ? 176.350 183.772 125.171 1.00 98.14  ? 474 ILE C CA  1 
ATOM   10425 C C   . ILE C 1 453 ? 175.161 183.452 124.274 1.00 98.14  ? 474 ILE C C   1 
ATOM   10426 O O   . ILE C 1 453 ? 175.276 183.474 123.041 1.00 98.14  ? 474 ILE C O   1 
ATOM   10427 C CB  . ILE C 1 453 ? 176.931 182.513 125.846 1.00 98.14  ? 474 ILE C CB  1 
ATOM   10428 C CG1 . ILE C 1 453 ? 178.314 182.810 126.433 1.00 98.14  ? 474 ILE C CG1 1 
ATOM   10429 C CG2 . ILE C 1 453 ? 177.035 181.358 124.866 1.00 98.14  ? 474 ILE C CG2 1 
ATOM   10430 C CD1 . ILE C 1 453 ? 178.839 181.729 127.355 1.00 98.14  ? 474 ILE C CD1 1 
ATOM   10431 N N   . LEU C 1 454 ? 173.981 183.223 124.876 1.00 93.40  ? 475 LEU C N   1 
ATOM   10432 C CA  . LEU C 1 454 ? 172.742 183.031 124.117 1.00 93.40  ? 475 LEU C CA  1 
ATOM   10433 C C   . LEU C 1 454 ? 172.337 184.255 123.304 1.00 93.40  ? 475 LEU C C   1 
ATOM   10434 O O   . LEU C 1 454 ? 171.553 184.114 122.359 1.00 93.40  ? 475 LEU C O   1 
ATOM   10435 C CB  . LEU C 1 454 ? 171.582 182.637 125.038 1.00 93.40  ? 475 LEU C CB  1 
ATOM   10436 C CG  . LEU C 1 454 ? 171.496 181.224 125.621 1.00 93.40  ? 475 LEU C CG  1 
ATOM   10437 C CD1 . LEU C 1 454 ? 170.418 181.170 126.687 1.00 93.40  ? 475 LEU C CD1 1 
ATOM   10438 C CD2 . LEU C 1 454 ? 171.178 180.222 124.529 1.00 93.40  ? 475 LEU C CD2 1 
ATOM   10439 N N   . ASP C 1 455 ? 172.834 185.445 123.648 1.00 100.58 ? 476 ASP C N   1 
ATOM   10440 C CA  . ASP C 1 455 ? 172.694 186.579 122.741 1.00 100.58 ? 476 ASP C CA  1 
ATOM   10441 C C   . ASP C 1 455 ? 173.535 186.382 121.485 1.00 100.58 ? 476 ASP C C   1 
ATOM   10442 O O   . ASP C 1 455 ? 173.029 186.527 120.366 1.00 100.58 ? 476 ASP C O   1 
ATOM   10443 C CB  . ASP C 1 455 ? 173.086 187.875 123.449 1.00 100.58 ? 476 ASP C CB  1 
ATOM   10444 C CG  . ASP C 1 455 ? 172.064 188.309 124.480 1.00 100.58 ? 476 ASP C CG  1 
ATOM   10445 O OD1 . ASP C 1 455 ? 170.943 187.760 124.477 1.00 100.58 ? 476 ASP C OD1 1 
ATOM   10446 O OD2 . ASP C 1 455 ? 172.384 189.201 125.294 1.00 100.58 ? 476 ASP C OD2 1 
ATOM   10447 N N   . MET C 1 456 ? 174.810 186.016 121.643 1.00 99.17  ? 477 MET C N   1 
ATOM   10448 C CA  . MET C 1 456 ? 175.678 185.909 120.475 1.00 99.17  ? 477 MET C CA  1 
ATOM   10449 C C   . MET C 1 456 ? 175.414 184.604 119.728 1.00 99.17  ? 477 MET C C   1 
ATOM   10450 O O   . MET C 1 456 ? 175.740 184.485 118.539 1.00 99.17  ? 477 MET C O   1 
ATOM   10451 C CB  . MET C 1 456 ? 177.143 186.040 120.912 1.00 99.17  ? 477 MET C CB  1 
ATOM   10452 C CG  . MET C 1 456 ? 178.162 186.178 119.783 1.00 99.17  ? 477 MET C CG  1 
ATOM   10453 S SD  . MET C 1 456 ? 177.928 187.736 118.901 1.00 99.17  ? 477 MET C SD  1 
ATOM   10454 C CE  . MET C 1 456 ? 178.657 187.361 117.310 1.00 99.17  ? 477 MET C CE  1 
ATOM   10455 N N   . ILE C 1 457 ? 174.794 183.636 120.410 1.00 98.06  ? 478 ILE C N   1 
ATOM   10456 C CA  . ILE C 1 457 ? 174.169 182.491 119.754 1.00 98.06  ? 478 ILE C CA  1 
ATOM   10457 C C   . ILE C 1 457 ? 173.107 182.946 118.758 1.00 98.06  ? 478 ILE C C   1 
ATOM   10458 O O   . ILE C 1 457 ? 173.044 182.434 117.631 1.00 98.06  ? 478 ILE C O   1 
ATOM   10459 C CB  . ILE C 1 457 ? 173.610 181.542 120.834 1.00 98.06  ? 478 ILE C CB  1 
ATOM   10460 C CG1 . ILE C 1 457 ? 174.743 180.683 121.417 1.00 98.06  ? 478 ILE C CG1 1 
ATOM   10461 C CG2 . ILE C 1 457 ? 172.390 180.754 120.349 1.00 98.06  ? 478 ILE C CG2 1 
ATOM   10462 C CD1 . ILE C 1 457 ? 174.370 179.913 122.660 1.00 98.06  ? 478 ILE C CD1 1 
ATOM   10463 N N   . THR C 1 458 ? 172.312 183.963 119.112 1.00 95.18  ? 479 THR C N   1 
ATOM   10464 C CA  . THR C 1 458 ? 171.390 184.539 118.138 1.00 95.18  ? 479 THR C CA  1 
ATOM   10465 C C   . THR C 1 458 ? 172.101 185.395 117.095 1.00 95.18  ? 479 THR C C   1 
ATOM   10466 O O   . THR C 1 458 ? 171.462 185.815 116.125 1.00 95.18  ? 479 THR C O   1 
ATOM   10467 C CB  . THR C 1 458 ? 170.304 185.362 118.836 1.00 95.18  ? 479 THR C CB  1 
ATOM   10468 O OG1 . THR C 1 458 ? 170.901 186.420 119.593 1.00 95.18  ? 479 THR C OG1 1 
ATOM   10469 C CG2 . THR C 1 458 ? 169.481 184.480 119.764 1.00 95.18  ? 479 THR C CG2 1 
ATOM   10470 N N   . GLY C 1 459 ? 173.399 185.654 117.267 1.00 92.28  ? 480 GLY C N   1 
ATOM   10471 C CA  . GLY C 1 459 ? 174.230 186.201 116.214 1.00 92.28  ? 480 GLY C CA  1 
ATOM   10472 C C   . GLY C 1 459 ? 174.835 185.124 115.333 1.00 92.28  ? 480 GLY C C   1 
ATOM   10473 O O   . GLY C 1 459 ? 175.759 185.392 114.560 1.00 92.28  ? 480 GLY C O   1 
ATOM   10474 N N   . GLY C 1 460 ? 174.326 183.894 115.447 1.00 95.94  ? 481 GLY C N   1 
ATOM   10475 C CA  . GLY C 1 460 ? 174.709 182.820 114.547 1.00 95.94  ? 481 GLY C CA  1 
ATOM   10476 C C   . GLY C 1 460 ? 174.038 182.872 113.189 1.00 95.94  ? 481 GLY C C   1 
ATOM   10477 O O   . GLY C 1 460 ? 174.364 182.050 112.326 1.00 95.94  ? 481 GLY C O   1 
ATOM   10478 N N   . LEU C 1 461 ? 173.107 183.802 112.989 1.00 98.83  ? 482 LEU C N   1 
ATOM   10479 C CA  . LEU C 1 461 ? 172.427 183.977 111.712 1.00 98.83  ? 482 LEU C CA  1 
ATOM   10480 C C   . LEU C 1 461 ? 173.376 184.512 110.644 1.00 98.83  ? 482 LEU C C   1 
ATOM   10481 O O   . LEU C 1 461 ? 173.082 185.506 109.980 1.00 98.83  ? 482 LEU C O   1 
ATOM   10482 C CB  . LEU C 1 461 ? 171.236 184.925 111.871 1.00 98.83  ? 482 LEU C CB  1 
ATOM   10483 C CG  . LEU C 1 461 ? 170.103 184.465 112.791 1.00 98.83  ? 482 LEU C CG  1 
ATOM   10484 C CD1 . LEU C 1 461 ? 169.078 185.574 112.971 1.00 98.83  ? 482 LEU C CD1 1 
ATOM   10485 C CD2 . LEU C 1 461 ? 169.446 183.209 112.243 1.00 98.83  ? 482 LEU C CD2 1 
HETATM 10486 C C1  . NAG D 2 .   ? 176.925 192.786 225.436 1.00 133.88 ? 1   NAG D C1  1 
HETATM 10487 C C2  . NAG D 2 .   ? 176.986 193.301 226.878 1.00 133.88 ? 1   NAG D C2  1 
HETATM 10488 C C3  . NAG D 2 .   ? 175.570 193.658 227.344 1.00 133.88 ? 1   NAG D C3  1 
HETATM 10489 C C4  . NAG D 2 .   ? 174.871 194.634 226.365 1.00 133.88 ? 1   NAG D C4  1 
HETATM 10490 C C5  . NAG D 2 .   ? 175.073 194.161 224.907 1.00 133.88 ? 1   NAG D C5  1 
HETATM 10491 C C6  . NAG D 2 .   ? 174.582 195.140 223.862 1.00 133.88 ? 1   NAG D C6  1 
HETATM 10492 C C7  . NAG D 2 .   ? 178.835 192.589 228.318 1.00 133.88 ? 1   NAG D C7  1 
HETATM 10493 C C8  . NAG D 2 .   ? 179.347 191.489 229.214 1.00 133.88 ? 1   NAG D C8  1 
HETATM 10494 N N2  . NAG D 2 .   ? 177.631 192.364 227.760 1.00 133.88 ? 1   NAG D N2  1 
HETATM 10495 O O3  . NAG D 2 .   ? 175.787 194.138 228.648 1.00 133.88 ? 1   NAG D O3  1 
HETATM 10496 O O4  . NAG D 2 .   ? 173.463 194.757 226.562 1.00 133.88 ? 1   NAG D O4  1 
HETATM 10497 O O5  . NAG D 2 .   ? 176.436 193.851 224.648 1.00 133.88 ? 1   NAG D O5  1 
HETATM 10498 O O6  . NAG D 2 .   ? 173.177 195.214 223.910 1.00 133.88 ? 1   NAG D O6  1 
HETATM 10499 O O7  . NAG D 2 .   ? 179.484 193.607 228.124 1.00 133.88 ? 1   NAG D O7  1 
HETATM 10500 C C1  . NAG D 2 .   ? 172.975 195.420 227.761 1.00 157.29 ? 2   NAG D C1  1 
HETATM 10501 C C2  . NAG D 2 .   ? 172.782 196.948 227.606 1.00 157.29 ? 2   NAG D C2  1 
HETATM 10502 C C3  . NAG D 2 .   ? 172.067 197.530 228.839 1.00 157.29 ? 2   NAG D C3  1 
HETATM 10503 C C4  . NAG D 2 .   ? 170.877 196.722 229.372 1.00 157.29 ? 2   NAG D C4  1 
HETATM 10504 C C5  . NAG D 2 .   ? 171.211 195.217 229.361 1.00 157.29 ? 2   NAG D C5  1 
HETATM 10505 C C6  . NAG D 2 .   ? 170.059 194.272 229.642 1.00 157.29 ? 2   NAG D C6  1 
HETATM 10506 C C7  . NAG D 2 .   ? 175.133 197.774 228.106 1.00 157.29 ? 2   NAG D C7  1 
HETATM 10507 C C8  . NAG D 2 .   ? 176.193 198.668 227.512 1.00 157.29 ? 2   NAG D C8  1 
HETATM 10508 N N2  . NAG D 2 .   ? 174.000 197.698 227.364 1.00 157.29 ? 2   NAG D N2  1 
HETATM 10509 O O3  . NAG D 2 .   ? 171.696 198.849 228.527 1.00 157.29 ? 2   NAG D O3  1 
HETATM 10510 O O4  . NAG D 2 .   ? 170.682 197.222 230.681 1.00 157.29 ? 2   NAG D O4  1 
HETATM 10511 O O5  . NAG D 2 .   ? 171.720 194.866 228.089 1.00 157.29 ? 2   NAG D O5  1 
HETATM 10512 O O6  . NAG D 2 .   ? 170.467 192.942 229.428 1.00 157.29 ? 2   NAG D O6  1 
HETATM 10513 O O7  . NAG D 2 .   ? 175.344 197.201 229.168 1.00 157.29 ? 2   NAG D O7  1 
HETATM 10514 C C1  . BMA D 2 .   ? 169.310 197.607 230.968 1.00 174.12 ? 3   BMA D C1  1 
HETATM 10515 C C2  . BMA D 2 .   ? 169.343 198.727 232.012 1.00 174.12 ? 3   BMA D C2  1 
HETATM 10516 C C3  . BMA D 2 .   ? 167.902 199.181 232.380 1.00 174.12 ? 3   BMA D C3  1 
HETATM 10517 C C4  . BMA D 2 .   ? 166.791 198.912 231.333 1.00 174.12 ? 3   BMA D C4  1 
HETATM 10518 C C5  . BMA D 2 .   ? 167.314 198.672 229.909 1.00 174.12 ? 3   BMA D C5  1 
HETATM 10519 C C6  . BMA D 2 .   ? 167.283 199.935 229.053 1.00 174.12 ? 3   BMA D C6  1 
HETATM 10520 O O2  . BMA D 2 .   ? 170.127 199.776 231.509 1.00 174.12 ? 3   BMA D O2  1 
HETATM 10521 O O3  . BMA D 2 .   ? 168.001 200.541 232.726 1.00 174.12 ? 3   BMA D O3  1 
HETATM 10522 O O4  . BMA D 2 .   ? 166.080 197.784 231.809 1.00 174.12 ? 3   BMA D O4  1 
HETATM 10523 O O5  . BMA D 2 .   ? 168.609 198.070 229.815 1.00 174.12 ? 3   BMA D O5  1 
HETATM 10524 O O6  . BMA D 2 .   ? 166.965 199.547 227.734 1.00 174.12 ? 3   BMA D O6  1 
HETATM 10525 C C1  . NAG E 3 .   ? 190.823 213.524 190.163 1.00 97.11  ? 1   NAG E C1  1 
HETATM 10526 C C2  . NAG E 3 .   ? 192.303 213.395 189.769 1.00 97.11  ? 1   NAG E C2  1 
HETATM 10527 C C3  . NAG E 3 .   ? 193.193 213.957 190.885 1.00 97.11  ? 1   NAG E C3  1 
HETATM 10528 C C4  . NAG E 3 .   ? 192.803 215.389 191.275 1.00 97.11  ? 1   NAG E C4  1 
HETATM 10529 C C5  . NAG E 3 .   ? 191.284 215.471 191.508 1.00 97.11  ? 1   NAG E C5  1 
HETATM 10530 C C6  . NAG E 3 .   ? 190.789 216.886 191.715 1.00 97.11  ? 1   NAG E C6  1 
HETATM 10531 C C7  . NAG E 3 .   ? 192.848 210.909 190.012 1.00 97.11  ? 1   NAG E C7  1 
HETATM 10532 C C8  . NAG E 3 .   ? 193.183 209.734 189.127 1.00 97.11  ? 1   NAG E C8  1 
HETATM 10533 N N2  . NAG E 3 .   ? 192.643 212.058 189.325 1.00 97.11  ? 1   NAG E N2  1 
HETATM 10534 O O3  . NAG E 3 .   ? 194.516 213.836 190.431 1.00 97.11  ? 1   NAG E O3  1 
HETATM 10535 O O4  . NAG E 3 .   ? 193.494 215.739 192.456 1.00 97.11  ? 1   NAG E O4  1 
HETATM 10536 O O5  . NAG E 3 .   ? 190.594 214.901 190.406 1.00 97.11  ? 1   NAG E O5  1 
HETATM 10537 O O6  . NAG E 3 .   ? 191.520 217.754 190.881 1.00 97.11  ? 1   NAG E O6  1 
HETATM 10538 O O7  . NAG E 3 .   ? 192.785 210.765 191.225 1.00 97.11  ? 1   NAG E O7  1 
HETATM 10539 C C1  . NAG E 3 .   ? 194.598 216.621 192.172 1.00 126.67 ? 2   NAG E C1  1 
HETATM 10540 C C2  . NAG E 3 .   ? 194.870 217.499 193.406 1.00 126.67 ? 2   NAG E C2  1 
HETATM 10541 C C3  . NAG E 3 .   ? 196.160 218.307 193.205 1.00 126.67 ? 2   NAG E C3  1 
HETATM 10542 C C4  . NAG E 3 .   ? 197.339 217.383 192.860 1.00 126.67 ? 2   NAG E C4  1 
HETATM 10543 C C5  . NAG E 3 .   ? 196.947 216.591 191.602 1.00 126.67 ? 2   NAG E C5  1 
HETATM 10544 C C6  . NAG E 3 .   ? 197.998 215.619 191.114 1.00 126.67 ? 2   NAG E C6  1 
HETATM 10545 C C7  . NAG E 3 .   ? 193.151 219.340 193.111 1.00 126.67 ? 2   NAG E C7  1 
HETATM 10546 C C8  . NAG E 3 .   ? 191.996 219.965 193.854 1.00 126.67 ? 2   NAG E C8  1 
HETATM 10547 N N2  . NAG E 3 .   ? 193.746 218.329 193.783 1.00 126.67 ? 2   NAG E N2  1 
HETATM 10548 O O3  . NAG E 3 .   ? 196.311 219.082 194.367 1.00 126.67 ? 2   NAG E O3  1 
HETATM 10549 O O4  . NAG E 3 .   ? 198.513 218.134 192.623 1.00 126.67 ? 2   NAG E O4  1 
HETATM 10550 O O5  . NAG E 3 .   ? 195.754 215.869 191.860 1.00 126.67 ? 2   NAG E O5  1 
HETATM 10551 O O6  . NAG E 3 .   ? 197.474 214.856 190.053 1.00 126.67 ? 2   NAG E O6  1 
HETATM 10552 O O7  . NAG E 3 .   ? 193.471 219.752 192.005 1.00 126.67 ? 2   NAG E O7  1 
HETATM 10553 C C1  . BMA E 3 .   ? 199.363 218.126 193.798 1.00 156.23 ? 3   BMA E C1  1 
HETATM 10554 C C2  . BMA E 3 .   ? 200.558 217.194 193.588 1.00 156.23 ? 3   BMA E C2  1 
HETATM 10555 C C3  . BMA E 3 .   ? 201.500 217.242 194.827 1.00 156.23 ? 3   BMA E C3  1 
HETATM 10556 C C4  . BMA E 3 .   ? 201.482 218.536 195.683 1.00 156.23 ? 3   BMA E C4  1 
HETATM 10557 C C5  . BMA E 3 .   ? 200.859 219.750 194.982 1.00 156.23 ? 3   BMA E C5  1 
HETATM 10558 C C6  . BMA E 3 .   ? 201.889 220.648 194.300 1.00 156.23 ? 3   BMA E C6  1 
HETATM 10559 O O2  . BMA E 3 .   ? 201.207 217.553 192.398 1.00 156.23 ? 3   BMA E O2  1 
HETATM 10560 O O3  . BMA E 3 .   ? 202.787 216.930 194.353 1.00 156.23 ? 3   BMA E O3  1 
HETATM 10561 O O4  . BMA E 3 .   ? 200.754 218.211 196.853 1.00 156.23 ? 3   BMA E O4  1 
HETATM 10562 O O5  . BMA E 3 .   ? 199.819 219.451 194.054 1.00 156.23 ? 3   BMA E O5  1 
HETATM 10563 O O6  . BMA E 3 .   ? 202.530 221.399 195.307 1.00 156.23 ? 3   BMA E O6  1 
HETATM 10564 C C1  . FUC E 3 .   ? 190.630 218.393 189.943 1.00 120.62 ? 4   FUC E C1  1 
HETATM 10565 C C2  . FUC E 3 .   ? 191.316 219.665 189.429 1.00 120.62 ? 4   FUC E C2  1 
HETATM 10566 C C3  . FUC E 3 .   ? 192.556 219.274 188.622 1.00 120.62 ? 4   FUC E C3  1 
HETATM 10567 C C4  . FUC E 3 .   ? 192.189 218.342 187.462 1.00 120.62 ? 4   FUC E C4  1 
HETATM 10568 C C5  . FUC E 3 .   ? 191.437 217.129 188.026 1.00 120.62 ? 4   FUC E C5  1 
HETATM 10569 C C6  . FUC E 3 .   ? 190.867 216.222 186.955 1.00 120.62 ? 4   FUC E C6  1 
HETATM 10570 O O2  . FUC E 3 .   ? 191.619 220.484 190.527 1.00 120.62 ? 4   FUC E O2  1 
HETATM 10571 O O3  . FUC E 3 .   ? 193.176 220.463 188.197 1.00 120.62 ? 4   FUC E O3  1 
HETATM 10572 O O4  . FUC E 3 .   ? 191.425 219.076 186.538 1.00 120.62 ? 4   FUC E O4  1 
HETATM 10573 O O5  . FUC E 3 .   ? 190.347 217.546 188.852 1.00 120.62 ? 4   FUC E O5  1 
HETATM 10574 C C1  . NAG F 2 .   ? 188.447 168.834 226.552 1.00 123.61 ? 1   NAG F C1  1 
HETATM 10575 C C2  . NAG F 2 .   ? 188.817 168.702 228.037 1.00 123.61 ? 1   NAG F C2  1 
HETATM 10576 C C3  . NAG F 2 .   ? 189.810 169.812 228.401 1.00 123.61 ? 1   NAG F C3  1 
HETATM 10577 C C4  . NAG F 2 .   ? 191.037 169.818 227.459 1.00 123.61 ? 1   NAG F C4  1 
HETATM 10578 C C5  . NAG F 2 .   ? 190.556 169.741 225.992 1.00 123.61 ? 1   NAG F C5  1 
HETATM 10579 C C6  . NAG F 2 .   ? 191.668 169.627 224.973 1.00 123.61 ? 1   NAG F C6  1 
HETATM 10580 C C7  . NAG F 2 .   ? 187.401 167.756 229.802 1.00 123.61 ? 1   NAG F C7  1 
HETATM 10581 C C8  . NAG F 2 .   ? 186.138 167.951 230.603 1.00 123.61 ? 1   NAG F C8  1 
HETATM 10582 N N2  . NAG F 2 .   ? 187.661 168.715 228.893 1.00 123.61 ? 1   NAG F N2  1 
HETATM 10583 O O3  . NAG F 2 .   ? 190.082 169.574 229.760 1.00 123.61 ? 1   NAG F O3  1 
HETATM 10584 O O4  . NAG F 2 .   ? 191.846 170.986 227.570 1.00 123.61 ? 1   NAG F O4  1 
HETATM 10585 O O5  . NAG F 2 .   ? 189.640 168.667 225.814 1.00 123.61 ? 1   NAG F O5  1 
HETATM 10586 O O6  . NAG F 2 .   ? 192.386 170.837 224.928 1.00 123.61 ? 1   NAG F O6  1 
HETATM 10587 O O7  . NAG F 2 .   ? 188.127 166.789 229.983 1.00 123.61 ? 1   NAG F O7  1 
HETATM 10588 C C1  . NAG F 2 .   ? 192.709 171.140 228.731 1.00 152.45 ? 2   NAG F C1  1 
HETATM 10589 C C2  . NAG F 2 .   ? 194.112 170.514 228.567 1.00 152.45 ? 2   NAG F C2  1 
HETATM 10590 C C3  . NAG F 2 .   ? 195.029 170.943 229.721 1.00 152.45 ? 2   NAG F C3  1 
HETATM 10591 C C4  . NAG F 2 .   ? 194.977 172.427 230.097 1.00 152.45 ? 2   NAG F C4  1 
HETATM 10592 C C5  . NAG F 2 .   ? 193.515 172.896 230.154 1.00 152.45 ? 2   NAG F C5  1 
HETATM 10593 C C6  . NAG F 2 .   ? 193.323 174.388 230.333 1.00 152.45 ? 2   NAG F C6  1 
HETATM 10594 C C7  . NAG F 2 .   ? 194.303 168.274 227.516 1.00 152.45 ? 2   NAG F C7  1 
HETATM 10595 C C8  . NAG F 2 .   ? 194.213 166.797 227.809 1.00 152.45 ? 2   NAG F C8  1 
HETATM 10596 N N2  . NAG F 2 .   ? 194.086 169.074 228.576 1.00 152.45 ? 2   NAG F N2  1 
HETATM 10597 O O3  . NAG F 2 .   ? 196.335 170.541 229.394 1.00 152.45 ? 2   NAG F O3  1 
HETATM 10598 O O4  . NAG F 2 .   ? 195.604 172.511 231.360 1.00 152.45 ? 2   NAG F O4  1 
HETATM 10599 O O5  . NAG F 2 .   ? 192.869 172.526 228.953 1.00 152.45 ? 2   NAG F O5  1 
HETATM 10600 O O6  . NAG F 2 .   ? 191.987 174.736 230.057 1.00 152.45 ? 2   NAG F O6  1 
HETATM 10601 O O7  . NAG F 2 .   ? 194.554 168.688 226.395 1.00 152.45 ? 2   NAG F O7  1 
HETATM 10602 C C1  . BMA F 2 .   ? 196.739 173.413 231.358 1.00 170.57 ? 3   BMA F C1  1 
HETATM 10603 C C2  . BMA F 2 .   ? 197.607 173.069 232.569 1.00 170.57 ? 3   BMA F C2  1 
HETATM 10604 C C3  . BMA F 2 .   ? 198.872 173.971 232.631 1.00 170.57 ? 3   BMA F C3  1 
HETATM 10605 C C4  . BMA F 2 .   ? 199.339 174.615 231.301 1.00 170.57 ? 3   BMA F C4  1 
HETATM 10606 C C5  . BMA F 2 .   ? 198.797 173.929 230.036 1.00 170.57 ? 3   BMA F C5  1 
HETATM 10607 C C6  . BMA F 2 .   ? 199.782 172.957 229.380 1.00 170.57 ? 3   BMA F C6  1 
HETATM 10608 O O2  . BMA F 2 .   ? 197.927 171.706 232.497 1.00 170.57 ? 3   BMA F O2  1 
HETATM 10609 O O3  . BMA F 2 .   ? 199.875 173.175 233.213 1.00 170.57 ? 3   BMA F O3  1 
HETATM 10610 O O4  . BMA F 2 .   ? 198.910 175.962 231.365 1.00 170.57 ? 3   BMA F O4  1 
HETATM 10611 O O5  . BMA F 2 .   ? 197.519 173.300 230.173 1.00 170.57 ? 3   BMA F O5  1 
HETATM 10612 O O6  . BMA F 2 .   ? 200.266 172.039 230.338 1.00 170.57 ? 3   BMA F O6  1 
HETATM 10613 C C1  . NAG G 3 .   ? 200.297 143.623 193.538 1.00 106.84 ? 1   NAG G C1  1 
HETATM 10614 C C2  . NAG G 3 .   ? 199.365 142.420 193.309 1.00 106.84 ? 1   NAG G C2  1 
HETATM 10615 C C3  . NAG G 3 .   ? 199.444 141.433 194.487 1.00 106.84 ? 1   NAG G C3  1 
HETATM 10616 C C4  . NAG G 3 .   ? 200.877 140.971 194.758 1.00 106.84 ? 1   NAG G C4  1 
HETATM 10617 C C5  . NAG G 3 .   ? 201.816 142.182 194.829 1.00 106.84 ? 1   NAG G C5  1 
HETATM 10618 C C6  . NAG G 3 .   ? 203.271 141.782 194.755 1.00 106.84 ? 1   NAG G C6  1 
HETATM 10619 C C7  . NAG G 3 .   ? 196.927 143.178 193.578 1.00 106.84 ? 1   NAG G C7  1 
HETATM 10620 C C8  . NAG G 3 .   ? 195.748 143.475 192.685 1.00 106.84 ? 1   NAG G C8  1 
HETATM 10621 N N2  . NAG G 3 .   ? 198.028 142.799 192.889 1.00 106.84 ? 1   NAG G N2  1 
HETATM 10622 O O3  . NAG G 3 .   ? 198.580 140.368 194.185 1.00 106.84 ? 1   NAG G O3  1 
HETATM 10623 O O4  . NAG G 3 .   ? 200.895 140.269 195.985 1.00 106.84 ? 1   NAG G O4  1 
HETATM 10624 O O5  . NAG G 3 .   ? 201.578 143.058 193.743 1.00 106.84 ? 1   NAG G O5  1 
HETATM 10625 O O6  . NAG G 3 .   ? 203.424 140.782 193.772 1.00 106.84 ? 1   NAG G O6  1 
HETATM 10626 O O7  . NAG G 3 .   ? 196.823 143.292 194.792 1.00 106.84 ? 1   NAG G O7  1 
HETATM 10627 C C1  . NAG G 3 .   ? 201.064 138.851 195.779 1.00 140.55 ? 2   NAG G C1  1 
HETATM 10628 C C2  . NAG G 3 .   ? 201.846 138.260 196.970 1.00 140.55 ? 2   NAG G C2  1 
HETATM 10629 C C3  . NAG G 3 .   ? 201.837 136.723 196.936 1.00 140.55 ? 2   NAG G C3  1 
HETATM 10630 C C4  . NAG G 3 .   ? 200.435 136.146 196.714 1.00 140.55 ? 2   NAG G C4  1 
HETATM 10631 C C5  . NAG G 3 .   ? 199.816 136.816 195.479 1.00 140.55 ? 2   NAG G C5  1 
HETATM 10632 C C6  . NAG G 3 .   ? 198.405 136.370 195.167 1.00 140.55 ? 2   NAG G C6  1 
HETATM 10633 C C7  . NAG G 3 .   ? 204.236 138.695 196.232 1.00 140.55 ? 2   NAG G C7  1 
HETATM 10634 C C8  . NAG G 3 .   ? 205.484 139.388 196.720 1.00 140.55 ? 2   NAG G C8  1 
HETATM 10635 N N2  . NAG G 3 .   ? 203.190 138.790 197.086 1.00 140.55 ? 2   NAG G N2  1 
HETATM 10636 O O3  . NAG G 3 .   ? 202.423 136.280 198.133 1.00 140.55 ? 2   NAG G O3  1 
HETATM 10637 O O4  . NAG G 3 .   ? 200.556 134.750 196.537 1.00 140.55 ? 2   NAG G O4  1 
HETATM 10638 O O5  . NAG G 3 .   ? 199.805 138.221 195.673 1.00 140.55 ? 2   NAG G O5  1 
HETATM 10639 O O6  . NAG G 3 .   ? 197.876 137.166 194.134 1.00 140.55 ? 2   NAG G O6  1 
HETATM 10640 O O7  . NAG G 3 .   ? 204.231 138.120 195.151 1.00 140.55 ? 2   NAG G O7  1 
HETATM 10641 C C1  . BMA G 3 .   ? 199.999 134.056 197.677 1.00 155.88 ? 3   BMA G C1  1 
HETATM 10642 C C2  . BMA G 3 .   ? 199.480 132.697 197.203 1.00 155.88 ? 3   BMA G C2  1 
HETATM 10643 C C3  . BMA G 3 .   ? 199.000 131.827 198.399 1.00 155.88 ? 3   BMA G C3  1 
HETATM 10644 C C4  . BMA G 3 .   ? 199.610 132.139 199.788 1.00 155.88 ? 3   BMA G C4  1 
HETATM 10645 C C5  . BMA G 3 .   ? 200.911 132.950 199.741 1.00 155.88 ? 3   BMA G C5  1 
HETATM 10646 C C6  . BMA G 3 .   ? 202.166 132.078 199.731 1.00 155.88 ? 3   BMA G C6  1 
HETATM 10647 O O2  . BMA G 3 .   ? 200.495 132.075 196.463 1.00 155.88 ? 3   BMA G O2  1 
HETATM 10648 O O3  . BMA G 3 .   ? 199.210 130.490 198.011 1.00 155.88 ? 3   BMA G O3  1 
HETATM 10649 O O4  . BMA G 3 .   ? 198.607 132.844 200.496 1.00 155.88 ? 3   BMA G O4  1 
HETATM 10650 O O5  . BMA G 3 .   ? 200.995 133.903 198.682 1.00 155.88 ? 3   BMA G O5  1 
HETATM 10651 O O6  . BMA G 3 .   ? 202.266 131.459 200.995 1.00 155.88 ? 3   BMA G O6  1 
HETATM 10652 C C1  . FUC G 3 .   ? 204.415 141.200 192.809 1.00 138.41 ? 4   FUC G C1  1 
HETATM 10653 C C2  . FUC G 3 .   ? 205.120 139.948 192.263 1.00 138.41 ? 4   FUC G C2  1 
HETATM 10654 C C3  . FUC G 3 .   ? 204.137 139.123 191.429 1.00 138.41 ? 4   FUC G C3  1 
HETATM 10655 C C4  . FUC G 3 .   ? 203.521 139.963 190.303 1.00 138.41 ? 4   FUC G C4  1 
HETATM 10656 C C5  . FUC G 3 .   ? 202.874 141.207 190.923 1.00 138.41 ? 4   FUC G C5  1 
HETATM 10657 C C6  . FUC G 3 .   ? 202.349 142.185 189.891 1.00 138.41 ? 4   FUC G C6  1 
HETATM 10658 O O2  . FUC G 3 .   ? 205.657 139.227 193.340 1.00 138.41 ? 4   FUC G O2  1 
HETATM 10659 O O3  . FUC G 3 .   ? 204.831 137.993 190.957 1.00 138.41 ? 4   FUC G O3  1 
HETATM 10660 O O4  . FUC G 3 .   ? 204.535 140.279 189.381 1.00 138.41 ? 4   FUC G O4  1 
HETATM 10661 O O5  . FUC G 3 .   ? 203.817 141.904 191.741 1.00 138.41 ? 4   FUC G O5  1 
HETATM 10662 C C1  . NAG H 2 .   ? 161.345 170.805 226.683 1.00 137.89 ? 1   NAG H C1  1 
HETATM 10663 C C2  . NAG H 2 .   ? 161.423 170.806 228.210 1.00 137.89 ? 1   NAG H C2  1 
HETATM 10664 C C3  . NAG H 2 .   ? 161.559 169.378 228.740 1.00 137.89 ? 1   NAG H C3  1 
HETATM 10665 C C4  . NAG H 2 .   ? 160.622 168.345 228.071 1.00 137.89 ? 1   NAG H C4  1 
HETATM 10666 C C5  . NAG H 2 .   ? 160.404 168.642 226.571 1.00 137.89 ? 1   NAG H C5  1 
HETATM 10667 C C6  . NAG H 2 .   ? 159.238 167.899 225.957 1.00 137.89 ? 1   NAG H C6  1 
HETATM 10668 C C7  . NAG H 2 .   ? 162.348 172.771 229.368 1.00 137.89 ? 1   NAG H C7  1 
HETATM 10669 C C8  . NAG H 2 .   ? 163.629 173.466 229.757 1.00 137.89 ? 1   NAG H C8  1 
HETATM 10670 N N2  . NAG H 2 .   ? 162.508 171.627 228.677 1.00 137.89 ? 1   NAG H N2  1 
HETATM 10671 O O3  . NAG H 2 .   ? 161.357 169.545 230.124 1.00 137.89 ? 1   NAG H O3  1 
HETATM 10672 O O4  . NAG H 2 .   ? 161.204 167.055 228.147 1.00 137.89 ? 1   NAG H O4  1 
HETATM 10673 O O5  . NAG H 2 .   ? 160.227 170.027 226.329 1.00 137.89 ? 1   NAG H O5  1 
HETATM 10674 O O6  . NAG H 2 .   ? 158.027 168.432 226.439 1.00 137.89 ? 1   NAG H O6  1 
HETATM 10675 O O7  . NAG H 2 .   ? 161.256 173.229 229.667 1.00 137.89 ? 1   NAG H O7  1 
HETATM 10676 C C1  . NAG H 2 .   ? 161.017 166.417 229.428 1.00 171.91 ? 2   NAG H C1  1 
HETATM 10677 C C2  . NAG H 2 .   ? 160.227 165.109 229.279 1.00 171.91 ? 2   NAG H C2  1 
HETATM 10678 C C3  . NAG H 2 .   ? 160.112 164.427 230.647 1.00 171.91 ? 2   NAG H C3  1 
HETATM 10679 C C4  . NAG H 2 .   ? 161.475 164.272 231.355 1.00 171.91 ? 2   NAG H C4  1 
HETATM 10680 C C5  . NAG H 2 .   ? 162.211 165.625 231.327 1.00 171.91 ? 2   NAG H C5  1 
HETATM 10681 C C6  . NAG H 2 .   ? 163.611 165.600 231.900 1.00 171.91 ? 2   NAG H C6  1 
HETATM 10682 C C7  . NAG H 2 .   ? 158.435 164.707 227.644 1.00 171.91 ? 2   NAG H C7  1 
HETATM 10683 C C8  . NAG H 2 .   ? 157.032 165.099 227.252 1.00 171.91 ? 2   NAG H C8  1 
HETATM 10684 N N2  . NAG H 2 .   ? 158.917 165.335 228.731 1.00 171.91 ? 2   NAG H N2  1 
HETATM 10685 O O3  . NAG H 2 .   ? 159.431 163.227 230.372 1.00 171.91 ? 2   NAG H O3  1 
HETATM 10686 O O4  . NAG H 2 .   ? 161.329 163.884 232.713 1.00 171.91 ? 2   NAG H O4  1 
HETATM 10687 O O5  . NAG H 2 .   ? 162.272 166.104 229.996 1.00 171.91 ? 2   NAG H O5  1 
HETATM 10688 O O6  . NAG H 2 .   ? 163.552 165.694 233.304 1.00 171.91 ? 2   NAG H O6  1 
HETATM 10689 O O7  . NAG H 2 .   ? 159.070 163.878 227.009 1.00 171.91 ? 2   NAG H O7  1 
HETATM 10690 C C1  . BMA H 2 .   ? 161.199 162.452 232.961 1.00 170.41 ? 3   BMA H C1  1 
HETATM 10691 C C2  . BMA H 2 .   ? 162.338 161.644 232.316 1.00 170.41 ? 3   BMA H C2  1 
HETATM 10692 C C3  . BMA H 2 .   ? 162.100 160.128 232.574 1.00 170.41 ? 3   BMA H C3  1 
HETATM 10693 C C4  . BMA H 2 .   ? 161.344 159.746 233.875 1.00 170.41 ? 3   BMA H C4  1 
HETATM 10694 C C5  . BMA H 2 .   ? 161.251 160.877 234.910 1.00 170.41 ? 3   BMA H C5  1 
HETATM 10695 C C6  . BMA H 2 .   ? 162.346 160.814 235.973 1.00 170.41 ? 3   BMA H C6  1 
HETATM 10696 O O2  . BMA H 2 .   ? 163.569 162.096 232.816 1.00 170.41 ? 3   BMA H O2  1 
HETATM 10697 O O3  . BMA H 2 .   ? 163.361 159.511 232.478 1.00 170.41 ? 3   BMA H O3  1 
HETATM 10698 O O4  . BMA H 2 .   ? 160.051 159.344 233.461 1.00 170.41 ? 3   BMA H O4  1 
HETATM 10699 O O5  . BMA H 2 .   ? 161.208 162.198 234.366 1.00 170.41 ? 3   BMA H O5  1 
HETATM 10700 O O6  . BMA H 2 .   ? 161.906 159.939 236.987 1.00 170.41 ? 3   BMA H O6  1 
HETATM 10701 C C1  . NAG I 3 .   ? 134.633 170.087 193.153 1.00 108.05 ? 1   NAG I C1  1 
HETATM 10702 C C2  . NAG I 3 .   ? 134.074 171.468 192.786 1.00 108.05 ? 1   NAG I C2  1 
HETATM 10703 C C3  . NAG I 3 .   ? 133.133 171.907 193.913 1.00 108.05 ? 1   NAG I C3  1 
HETATM 10704 C C4  . NAG I 3 .   ? 132.017 170.879 194.201 1.00 108.05 ? 1   NAG I C4  1 
HETATM 10705 C C5  . NAG I 3 .   ? 132.559 169.431 194.166 1.00 108.05 ? 1   NAG I C5  1 
HETATM 10706 C C6  . NAG I 3 .   ? 131.497 168.351 194.051 1.00 108.05 ? 1   NAG I C6  1 
HETATM 10707 C C7  . NAG I 3 .   ? 136.051 173.001 193.199 1.00 108.05 ? 1   NAG I C7  1 
HETATM 10708 C C8  . NAG I 3 .   ? 136.884 174.016 192.455 1.00 108.05 ? 1   NAG I C8  1 
HETATM 10709 N N2  . NAG I 3 .   ? 135.072 172.457 192.446 1.00 108.05 ? 1   NAG I N2  1 
HETATM 10710 O O3  . NAG I 3 .   ? 132.674 173.178 193.524 1.00 108.05 ? 1   NAG I O3  1 
HETATM 10711 O O4  . NAG I 3 .   ? 131.468 171.122 195.485 1.00 108.05 ? 1   NAG I O4  1 
HETATM 10712 O O5  . NAG I 3 .   ? 133.504 169.243 193.119 1.00 108.05 ? 1   NAG I O5  1 
HETATM 10713 O O6  . NAG I 3 .   ? 130.423 168.754 193.230 1.00 108.05 ? 1   NAG I O6  1 
HETATM 10714 O O7  . NAG I 3 .   ? 136.282 172.731 194.369 1.00 108.05 ? 1   NAG I O7  1 
HETATM 10715 C C1  . NAG I 3 .   ? 130.326 172.003 195.436 1.00 142.34 ? 2   NAG I C1  1 
HETATM 10716 C C2  . NAG I 3 .   ? 129.242 171.558 196.434 1.00 142.34 ? 2   NAG I C2  1 
HETATM 10717 C C3  . NAG I 3 .   ? 128.118 172.604 196.488 1.00 142.34 ? 2   NAG I C3  1 
HETATM 10718 C C4  . NAG I 3 .   ? 128.620 174.042 196.660 1.00 142.34 ? 2   NAG I C4  1 
HETATM 10719 C C5  . NAG I 3 .   ? 129.734 174.314 195.638 1.00 142.34 ? 2   NAG I C5  1 
HETATM 10720 C C6  . NAG I 3 .   ? 130.401 175.666 195.771 1.00 142.34 ? 2   NAG I C6  1 
HETATM 10721 C C7  . NAG I 3 .   ? 128.063 169.761 195.085 1.00 142.34 ? 2   NAG I C7  1 
HETATM 10722 C C8  . NAG I 3 .   ? 127.683 168.304 195.189 1.00 142.34 ? 2   NAG I C8  1 
HETATM 10723 N N2  . NAG I 3 .   ? 128.726 170.232 196.168 1.00 142.34 ? 2   NAG I N2  1 
HETATM 10724 O O3  . NAG I 3 .   ? 127.241 172.231 197.520 1.00 142.34 ? 2   NAG I O3  1 
HETATM 10725 O O4  . NAG I 3 .   ? 127.517 174.893 196.439 1.00 142.34 ? 2   NAG I O4  1 
HETATM 10726 O O5  . NAG I 3 .   ? 130.728 173.315 195.768 1.00 142.34 ? 2   NAG I O5  1 
HETATM 10727 O O6  . NAG I 3 .   ? 131.496 175.742 194.889 1.00 142.34 ? 2   NAG I O6  1 
HETATM 10728 O O7  . NAG I 3 .   ? 127.770 170.401 194.083 1.00 142.34 ? 2   NAG I O7  1 
HETATM 10729 C C1  . BMA I 3 .   ? 127.134 175.618 197.632 1.00 161.41 ? 3   BMA I C1  1 
HETATM 10730 C C2  . BMA I 3 .   ? 125.720 176.138 197.367 1.00 161.41 ? 3   BMA I C2  1 
HETATM 10731 C C3  . BMA I 3 .   ? 125.072 176.759 198.636 1.00 161.41 ? 3   BMA I C3  1 
HETATM 10732 C C4  . BMA I 3 .   ? 125.645 176.324 200.006 1.00 161.41 ? 3   BMA I C4  1 
HETATM 10733 C C5  . BMA I 3 .   ? 126.433 175.011 199.974 1.00 161.41 ? 3   BMA I C5  1 
HETATM 10734 C C6  . BMA I 3 .   ? 125.574 173.779 200.258 1.00 161.41 ? 3   BMA I C6  1 
HETATM 10735 O O2  . BMA I 3 .   ? 124.963 175.079 196.843 1.00 161.41 ? 3   BMA I O2  1 
HETATM 10736 O O3  . BMA I 3 .   ? 123.693 176.501 198.526 1.00 161.41 ? 3   BMA I O3  1 
HETATM 10737 O O4  . BMA I 3 .   ? 126.472 177.393 200.429 1.00 161.41 ? 3   BMA I O4  1 
HETATM 10738 O O5  . BMA I 3 .   ? 127.189 174.786 198.786 1.00 161.41 ? 3   BMA I O5  1 
HETATM 10739 O O6  . BMA I 3 .   ? 125.125 173.865 201.592 1.00 161.41 ? 3   BMA I O6  1 
HETATM 10740 C C1  . FUC I 3 .   ? 130.612 168.281 191.878 1.00 138.78 ? 4   FUC I C1  1 
HETATM 10741 C C2  . FUC I 3 .   ? 129.326 167.604 191.387 1.00 138.78 ? 4   FUC I C2  1 
HETATM 10742 C C3  . FUC I 3 .   ? 128.203 168.638 191.248 1.00 138.78 ? 4   FUC I C3  1 
HETATM 10743 C C4  . FUC I 3 .   ? 128.629 169.858 190.416 1.00 138.78 ? 4   FUC I C4  1 
HETATM 10744 C C5  . FUC I 3 .   ? 129.943 170.411 190.981 1.00 138.78 ? 4   FUC I C5  1 
HETATM 10745 C C6  . FUC I 3 .   ? 130.527 171.543 190.162 1.00 138.78 ? 4   FUC I C6  1 
HETATM 10746 O O2  . FUC I 3 .   ? 129.005 166.566 192.275 1.00 138.78 ? 4   FUC I O2  1 
HETATM 10747 O O3  . FUC I 3 .   ? 127.089 167.969 190.707 1.00 138.78 ? 4   FUC I O3  1 
HETATM 10748 O O4  . FUC I 3 .   ? 128.745 169.461 189.072 1.00 138.78 ? 4   FUC I O4  1 
HETATM 10749 O O5  . FUC I 3 .   ? 130.916 169.369 191.040 1.00 138.78 ? 4   FUC I O5  1 
HETATM 10750 C C1  . NAG J 4 .   ? 135.226 166.421 155.924 1.00 136.67 ? 601 NAG A C1  1 
HETATM 10751 C C2  . NAG J 4 .   ? 134.026 167.054 156.648 1.00 136.67 ? 601 NAG A C2  1 
HETATM 10752 C C3  . NAG J 4 .   ? 132.988 165.956 156.895 1.00 136.67 ? 601 NAG A C3  1 
HETATM 10753 C C4  . NAG J 4 .   ? 132.596 165.262 155.585 1.00 136.67 ? 601 NAG A C4  1 
HETATM 10754 C C5  . NAG J 4 .   ? 133.854 164.851 154.791 1.00 136.67 ? 601 NAG A C5  1 
HETATM 10755 C C6  . NAG J 4 .   ? 133.558 164.301 153.414 1.00 136.67 ? 601 NAG A C6  1 
HETATM 10756 C C7  . NAG J 4 .   ? 134.337 169.075 158.082 1.00 136.67 ? 601 NAG A C7  1 
HETATM 10757 C C8  . NAG J 4 .   ? 133.754 169.934 156.981 1.00 136.67 ? 601 NAG A C8  1 
HETATM 10758 N N2  . NAG J 4 .   ? 134.426 167.744 157.851 1.00 136.67 ? 601 NAG A N2  1 
HETATM 10759 O O3  . NAG J 4 .   ? 131.884 166.538 157.536 1.00 136.67 ? 601 NAG A O3  1 
HETATM 10760 O O4  . NAG J 4 .   ? 131.805 164.146 155.923 1.00 136.67 ? 601 NAG A O4  1 
HETATM 10761 O O5  . NAG J 4 .   ? 134.745 165.958 154.675 1.00 136.67 ? 601 NAG A O5  1 
HETATM 10762 O O6  . NAG J 4 .   ? 134.754 163.877 152.805 1.00 136.67 ? 601 NAG A O6  1 
HETATM 10763 O O7  . NAG J 4 .   ? 134.702 169.591 159.127 1.00 136.67 ? 601 NAG A O7  1 
HETATM 10764 C C1  . NAG K 4 .   ? 150.929 178.125 149.891 1.00 123.78 ? 602 NAG A C1  1 
HETATM 10765 C C2  . NAG K 4 .   ? 151.168 177.460 148.522 1.00 123.78 ? 602 NAG A C2  1 
HETATM 10766 C C3  . NAG K 4 .   ? 150.539 178.324 147.425 1.00 123.78 ? 602 NAG A C3  1 
HETATM 10767 C C4  . NAG K 4 .   ? 149.068 178.632 147.710 1.00 123.78 ? 602 NAG A C4  1 
HETATM 10768 C C5  . NAG K 4 .   ? 148.935 179.226 149.120 1.00 123.78 ? 602 NAG A C5  1 
HETATM 10769 C C6  . NAG K 4 .   ? 147.504 179.476 149.541 1.00 123.78 ? 602 NAG A C6  1 
HETATM 10770 C C7  . NAG K 4 .   ? 153.252 176.090 148.290 1.00 123.78 ? 602 NAG A C7  1 
HETATM 10771 C C8  . NAG K 4 .   ? 152.476 174.848 148.667 1.00 123.78 ? 602 NAG A C8  1 
HETATM 10772 N N2  . NAG K 4 .   ? 152.569 177.256 148.246 1.00 123.78 ? 602 NAG A N2  1 
HETATM 10773 O O3  . NAG K 4 .   ? 150.707 177.656 146.202 1.00 123.78 ? 602 NAG A O3  1 
HETATM 10774 O O4  . NAG K 4 .   ? 148.629 179.532 146.719 1.00 123.78 ? 602 NAG A O4  1 
HETATM 10775 O O5  . NAG K 4 .   ? 149.541 178.348 150.057 1.00 123.78 ? 602 NAG A O5  1 
HETATM 10776 O O6  . NAG K 4 .   ? 147.465 179.885 150.888 1.00 123.78 ? 602 NAG A O6  1 
HETATM 10777 O O7  . NAG K 4 .   ? 154.446 176.022 148.039 1.00 123.78 ? 602 NAG A O7  1 
HETATM 10778 C C1  . NAG L 4 .   ? 187.232 172.331 144.962 1.00 152.24 ? 603 NAG A C1  1 
HETATM 10779 C C2  . NAG L 4 .   ? 187.619 172.847 143.558 1.00 152.24 ? 603 NAG A C2  1 
HETATM 10780 C C3  . NAG L 4 .   ? 189.144 173.041 143.420 1.00 152.24 ? 603 NAG A C3  1 
HETATM 10781 C C4  . NAG L 4 .   ? 189.873 173.582 144.652 1.00 152.24 ? 603 NAG A C4  1 
HETATM 10782 C C5  . NAG L 4 .   ? 189.411 172.817 145.889 1.00 152.24 ? 603 NAG A C5  1 
HETATM 10783 C C6  . NAG L 4 .   ? 190.001 173.330 147.184 1.00 152.24 ? 603 NAG A C6  1 
HETATM 10784 C C7  . NAG L 4 .   ? 187.544 170.649 142.273 1.00 152.24 ? 603 NAG A C7  1 
HETATM 10785 C C8  . NAG L 4 .   ? 186.941 170.079 141.017 1.00 152.24 ? 603 NAG A C8  1 
HETATM 10786 N N2  . NAG L 4 .   ? 187.223 171.954 142.489 1.00 152.24 ? 603 NAG A N2  1 
HETATM 10787 O O3  . NAG L 4 .   ? 189.378 173.841 142.289 1.00 152.24 ? 603 NAG A O3  1 
HETATM 10788 O O4  . NAG L 4 .   ? 191.254 173.405 144.438 1.00 152.24 ? 603 NAG A O4  1 
HETATM 10789 O O5  . NAG L 4 .   ? 188.016 172.977 145.947 1.00 152.24 ? 603 NAG A O5  1 
HETATM 10790 O O6  . NAG L 4 .   ? 189.148 173.018 148.261 1.00 152.24 ? 603 NAG A O6  1 
HETATM 10791 O O7  . NAG L 4 .   ? 188.243 169.926 142.976 1.00 152.24 ? 603 NAG A O7  1 
HETATM 10792 C C1  . NAG M 4 .   ? 187.980 211.866 152.383 1.00 125.30 ? 601 NAG B C1  1 
HETATM 10793 C C2  . NAG M 4 .   ? 189.154 212.703 152.925 1.00 125.30 ? 601 NAG B C2  1 
HETATM 10794 C C3  . NAG M 4 .   ? 188.823 214.186 152.739 1.00 125.30 ? 601 NAG B C3  1 
HETATM 10795 C C4  . NAG M 4 .   ? 188.490 214.508 151.280 1.00 125.30 ? 601 NAG B C4  1 
HETATM 10796 C C5  . NAG M 4 .   ? 187.423 213.530 150.757 1.00 125.30 ? 601 NAG B C5  1 
HETATM 10797 C C6  . NAG M 4 .   ? 187.134 213.678 149.280 1.00 125.30 ? 601 NAG B C6  1 
HETATM 10798 C C7  . NAG M 4 .   ? 190.641 211.911 154.771 1.00 125.30 ? 601 NAG B C7  1 
HETATM 10799 C C8  . NAG M 4 .   ? 191.742 211.657 153.766 1.00 125.30 ? 601 NAG B C8  1 
HETATM 10800 N N2  . NAG M 4 .   ? 189.469 212.396 154.299 1.00 125.30 ? 601 NAG B N2  1 
HETATM 10801 O O3  . NAG M 4 .   ? 189.915 214.936 153.203 1.00 125.30 ? 601 NAG B O3  1 
HETATM 10802 O O4  . NAG M 4 .   ? 188.046 215.844 151.234 1.00 125.30 ? 601 NAG B O4  1 
HETATM 10803 O O5  . NAG M 4 .   ? 187.832 212.192 151.013 1.00 125.30 ? 601 NAG B O5  1 
HETATM 10804 O O6  . NAG M 4 .   ? 186.217 212.691 148.872 1.00 125.30 ? 601 NAG B O6  1 
HETATM 10805 O O7  . NAG M 4 .   ? 190.831 211.679 155.955 1.00 125.30 ? 601 NAG B O7  1 
HETATM 10806 C C1  . NAG N 4 .   ? 190.474 192.060 148.753 1.00 126.95 ? 602 NAG B C1  1 
HETATM 10807 C C2  . NAG N 4 .   ? 189.940 192.266 147.324 1.00 126.95 ? 602 NAG B C2  1 
HETATM 10808 C C3  . NAG N 4 .   ? 191.114 192.258 146.340 1.00 126.95 ? 602 NAG B C3  1 
HETATM 10809 C C4  . NAG N 4 .   ? 192.218 193.238 146.744 1.00 126.95 ? 602 NAG B C4  1 
HETATM 10810 C C5  . NAG N 4 .   ? 192.618 192.982 148.205 1.00 126.95 ? 602 NAG B C5  1 
HETATM 10811 C C6  . NAG N 4 .   ? 193.642 193.959 148.740 1.00 126.95 ? 602 NAG B C6  1 
HETATM 10812 C C7  . NAG N 4 .   ? 187.637 191.401 146.849 1.00 126.95 ? 602 NAG B C7  1 
HETATM 10813 C C8  . NAG N 4 .   ? 187.066 192.775 147.117 1.00 126.95 ? 602 NAG B C8  1 
HETATM 10814 N N2  . NAG N 4 .   ? 188.976 191.255 146.968 1.00 126.95 ? 602 NAG B N2  1 
HETATM 10815 O O3  . NAG N 4 .   ? 190.608 192.540 145.062 1.00 126.95 ? 602 NAG B O3  1 
HETATM 10816 O O4  . NAG N 4 .   ? 193.300 193.041 145.864 1.00 126.95 ? 602 NAG B O4  1 
HETATM 10817 O O5  . NAG N 4 .   ? 191.458 193.041 149.021 1.00 126.95 ? 602 NAG B O5  1 
HETATM 10818 O O6  . NAG N 4 .   ? 193.848 193.728 150.113 1.00 126.95 ? 602 NAG B O6  1 
HETATM 10819 O O7  . NAG N 4 .   ? 186.903 190.475 146.539 1.00 126.95 ? 602 NAG B O7  1 
HETATM 10820 C C1  . NAG O 4 .   ? 168.765 167.701 144.056 1.00 130.62 ? 603 NAG B C1  1 
HETATM 10821 C C2  . NAG O 4 .   ? 169.946 167.222 144.939 1.00 130.62 ? 603 NAG B C2  1 
HETATM 10822 C C3  . NAG O 4 .   ? 170.132 165.704 144.831 1.00 130.62 ? 603 NAG B C3  1 
HETATM 10823 C C4  . NAG O 4 .   ? 168.816 164.981 145.117 1.00 130.62 ? 603 NAG B C4  1 
HETATM 10824 C C5  . NAG O 4 .   ? 167.711 165.534 144.205 1.00 130.62 ? 603 NAG B C5  1 
HETATM 10825 C C6  . NAG O 4 .   ? 166.380 164.883 144.491 1.00 130.62 ? 603 NAG B C6  1 
HETATM 10826 C C7  . NAG O 4 .   ? 171.796 168.848 145.457 1.00 130.62 ? 603 NAG B C7  1 
HETATM 10827 C C8  . NAG O 4 .   ? 171.117 169.234 146.753 1.00 130.62 ? 603 NAG B C8  1 
HETATM 10828 N N2  . NAG O 4 .   ? 171.192 167.914 144.681 1.00 130.62 ? 603 NAG B N2  1 
HETATM 10829 O O3  . NAG O 4 .   ? 171.153 165.308 145.726 1.00 130.62 ? 603 NAG B O3  1 
HETATM 10830 O O4  . NAG O 4 .   ? 169.016 163.598 144.932 1.00 130.62 ? 603 NAG B O4  1 
HETATM 10831 O O5  . NAG O 4 .   ? 167.600 166.948 144.363 1.00 130.62 ? 603 NAG B O5  1 
HETATM 10832 O O6  . NAG O 4 .   ? 165.399 165.295 143.564 1.00 130.62 ? 603 NAG B O6  1 
HETATM 10833 O O7  . NAG O 4 .   ? 172.837 169.393 145.129 1.00 130.62 ? 603 NAG B O7  1 
HETATM 10834 C C1  . NAG P 4 .   ? 201.288 142.966 156.447 1.00 120.74 ? 601 NAG C C1  1 
HETATM 10835 C C2  . NAG P 4 .   ? 201.073 141.445 156.559 1.00 120.74 ? 601 NAG C C2  1 
HETATM 10836 C C3  . NAG P 4 .   ? 202.397 140.794 156.973 1.00 120.74 ? 601 NAG C C3  1 
HETATM 10837 C C4  . NAG P 4 .   ? 203.561 141.211 156.064 1.00 120.74 ? 601 NAG C C4  1 
HETATM 10838 C C5  . NAG P 4 .   ? 203.561 142.739 155.877 1.00 120.74 ? 601 NAG C C5  1 
HETATM 10839 C C6  . NAG P 4 .   ? 204.615 143.258 154.924 1.00 120.74 ? 601 NAG C C6  1 
HETATM 10840 C C7  . NAG P 4 .   ? 198.761 140.682 157.146 1.00 120.74 ? 601 NAG C C7  1 
HETATM 10841 C C8  . NAG P 4 .   ? 198.460 140.479 155.678 1.00 120.74 ? 601 NAG C C8  1 
HETATM 10842 N N2  . NAG P 4 .   ? 199.996 141.131 157.468 1.00 120.74 ? 601 NAG C N2  1 
HETATM 10843 O O3  . NAG P 4 .   ? 202.210 139.403 156.975 1.00 120.74 ? 601 NAG C O3  1 
HETATM 10844 O O4  . NAG P 4 .   ? 204.749 140.760 156.674 1.00 120.74 ? 601 NAG C O4  1 
HETATM 10845 O O5  . NAG P 4 .   ? 202.269 143.147 155.441 1.00 120.74 ? 601 NAG C O5  1 
HETATM 10846 O O6  . NAG P 4 .   ? 204.725 144.655 155.058 1.00 120.74 ? 601 NAG C O6  1 
HETATM 10847 O O7  . NAG P 4 .   ? 197.907 140.443 157.988 1.00 120.74 ? 601 NAG C O7  1 
HETATM 10848 C C1  . NAG Q 4 .   ? 182.801 150.364 151.215 1.00 112.57 ? 602 NAG C C1  1 
HETATM 10849 C C2  . NAG Q 4 .   ? 182.811 150.697 149.708 1.00 112.57 ? 602 NAG C C2  1 
HETATM 10850 C C3  . NAG Q 4 .   ? 182.351 149.465 148.924 1.00 112.57 ? 602 NAG C C3  1 
HETATM 10851 C C4  . NAG Q 4 .   ? 183.144 148.208 149.284 1.00 112.57 ? 602 NAG C C4  1 
HETATM 10852 C C5  . NAG Q 4 .   ? 183.142 148.020 150.808 1.00 112.57 ? 602 NAG C C5  1 
HETATM 10853 C C6  . NAG Q 4 .   ? 184.009 146.875 151.281 1.00 112.57 ? 602 NAG C C6  1 
HETATM 10854 C C7  . NAG Q 4 .   ? 182.327 153.037 148.951 1.00 112.57 ? 602 NAG C C7  1 
HETATM 10855 C C8  . NAG Q 4 .   ? 183.809 153.291 148.790 1.00 112.57 ? 602 NAG C C8  1 
HETATM 10856 N N2  . NAG Q 4 .   ? 181.955 151.810 149.380 1.00 112.57 ? 602 NAG C N2  1 
HETATM 10857 O O3  . NAG Q 4 .   ? 182.441 149.767 147.557 1.00 112.57 ? 602 NAG C O3  1 
HETATM 10858 O O4  . NAG Q 4 .   ? 182.532 147.123 148.626 1.00 112.57 ? 602 NAG C O4  1 
HETATM 10859 O O5  . NAG Q 4 .   ? 183.598 149.214 151.422 1.00 112.57 ? 602 NAG C O5  1 
HETATM 10860 O O6  . NAG Q 4 .   ? 184.223 146.978 152.669 1.00 112.57 ? 602 NAG C O6  1 
HETATM 10861 O O7  . NAG Q 4 .   ? 181.516 153.916 148.700 1.00 112.57 ? 602 NAG C O7  1 
HETATM 10862 C C1  . NAG R 4 .   ? 172.384 184.195 147.272 1.00 130.24 ? 603 NAG C C1  1 
HETATM 10863 C C2  . NAG R 4 .   ? 171.673 185.095 148.293 1.00 130.24 ? 603 NAG C C2  1 
HETATM 10864 C C3  . NAG R 4 .   ? 170.445 185.725 147.631 1.00 130.24 ? 603 NAG C C3  1 
HETATM 10865 C C4  . NAG R 4 .   ? 170.802 186.432 146.321 1.00 130.24 ? 603 NAG C C4  1 
HETATM 10866 C C5  . NAG R 4 .   ? 171.594 185.475 145.415 1.00 130.24 ? 603 NAG C C5  1 
HETATM 10867 C C6  . NAG R 4 .   ? 172.069 186.114 144.129 1.00 130.24 ? 603 NAG C C6  1 
HETATM 10868 C C7  . NAG R 4 .   ? 171.922 184.474 150.661 1.00 130.24 ? 603 NAG C C7  1 
HETATM 10869 C C8  . NAG R 4 .   ? 171.381 183.587 151.756 1.00 130.24 ? 603 NAG C C8  1 
HETATM 10870 N N2  . NAG R 4 .   ? 171.314 184.346 149.468 1.00 130.24 ? 603 NAG C N2  1 
HETATM 10871 O O3  . NAG R 4 .   ? 169.861 186.603 148.557 1.00 130.24 ? 603 NAG C O3  1 
HETATM 10872 O O4  . NAG R 4 .   ? 169.596 186.840 145.718 1.00 130.24 ? 603 NAG C O4  1 
HETATM 10873 O O5  . NAG R 4 .   ? 172.712 184.964 146.129 1.00 130.24 ? 603 NAG C O5  1 
HETATM 10874 O O6  . NAG R 4 .   ? 172.905 187.208 144.423 1.00 130.24 ? 603 NAG C O6  1 
HETATM 10875 O O7  . NAG R 4 .   ? 172.847 185.246 150.865 1.00 130.24 ? 603 NAG C O7  1 
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